source,canonical_rxn,catalyst1,solvent1,solvent2,reagent1,reagent2,dataset
US04618677,CCOC(=O)c1ccc(N=C=O)cc1.Cl.Cl.SCCCN1CCN(Cc2ccc(Cl)cc2)CC1>>CCOC(=O)c1ccc(NC(O)=[SH]CCCN2CCN(Cc3ccc(Cl)cc3)CC2)cc1.Cl.Cl,,ClCCl,,CCN(CC)CC,,test
US06187774B1,C=O.CC1(C)OC(=O)CC(=O)O1.c1cn2c(n1)CCCCC2>>O=C(O)CCc1cnc2n1CCCCC2,,CC#N,,O,,test
US04435405,Clc1nc2ccccc2cc1-c1ccccc1.NC(N)=S>>S=c1[nH]c2ccccc2cc1-c1ccccc1,,CCO,,CCOCC,,test
US20050090483A1,Brc1cccc2nccn12>>Brc1cccc2nccn12,,CCOC(C)=O,,Br,O=C([O-])O.[Na+],test
US20140249129A1,Cc1cc(C)c(S(=O)(=O)ON)c(C)c1.N#Cc1ccc(C2C3=C(CCCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C(=O)NC2CCS(=O)CC2)cc1>>N#Cc1ccc(C2C3=C(CCCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C(=O)NC2CCS(=N)(=O)CC2)cc1,,ClCCl,,,,test
US20150291655A1,CC(=O)NCC(C)(C)N1CCS(=O)(=O)CC1>>CC(C)(CN)N1CCS(=O)(=O)CC1,,CO,,[Na+].[OH-],,test
US20090170913A1,CC(C)N(C)c1nc2ccc([N+](=O)[O-])cc2s1>>CC(C)N(C)c1nc2ccc(N)cc2s1,[Pd],C1CCOC1,CCO,[H][H],,test
US20160264548A1,CC(C)(C)OC(=O)N1CCC(N)C1.N#Cc1cnc(Cl)nc1N>>CC(C)(C)OC(=O)N1CCC(Nc2ncc(C#N)c(N)n2)C1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20160068512A1,COC(=O)c1ccc(CN2CCC(Nc3ncnc4ccc(C(c5ccc(Cl)cc5)c5ccc(Cl)cc5)cc34)C2)cc1>>O=C(O)c1ccc(CN2CCC(Nc3ncnc4ccc(C(c5ccc(Cl)cc5)c5ccc(Cl)cc5)cc34)C2)cc1,,CO,,[Na+].[OH-],,test
US20050277652A1,COC(=O)c1cc(Cl)ccn1.O=[N+]([O-])c1ccc(O)c(F)c1>>COC(=O)c1cc(Oc2ccc([N+](=O)[O-])cc2F)ccn1,,Clc1ccccc1,,CO,,test
US20160002266A1,CCOC(=O)Cc1ccc(N)nc1>>Nc1ccc(CC(=O)O)cn1,,CCO,O,Cl,[K+].[OH-],test
US03978210,CCCCCCCCCCCCCCCC(=O)NC1CC(O)C(O)NC(=O)C2C(O)C(C)CN2C(=O)C(C(C)O)NC(=O)C(C(O)C(O)c2ccc(O)cc2)NC(=O)C2CC(O)CN2C(=O)C(C(C)O)NC1=O>>CCCCCCCCCCCCCCCC(=O)N[C@H]1C[C@@H](O)[C@@H](O)NC(=O)[C@@H]2[C@@H](O)[C@@H](C)CN2C(=O)[C@H]([C@@H](C)O)NC(=O)[C@H]([C@H](O)[C@@H](O)c2ccc(O)cc2)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H]([C@@H](C)O)NC1=O,,CCCCO,CCOC(C)=O,O,,test
US04861798,COc1ccc(CCCCCCCCC(=O)O)cc1>>O=C(O)CCCCCCCCc1ccc(O)cc1,,O,,Br,CC(=O)O,test
US05196428,CCOP(=O)(OCC)C1NC(=O)NC1=O.O=Cc1cc(OCCCNC(=O)NC2CCCCC2)ccc1[N+](=O)[O-]>>O=C1NC(=O)C(=Cc2cc(OCCCNC(=O)NC3CCCCC3)ccc2[N+](=O)[O-])N1,,CCO,,Cl,[Na],test
US20160009677A1,COC(=O)c1ccc(N)cc1F.O=C1CCC(=O)N1Br>>COC(=O)c1cc(Br)c(N)cc1F,,ClC(Cl)Cl,,,,test
US05602118,CC(O[Si](C)(C)C(C)(C)C)C1C(=O)N([Si](C)(C)C(C)(C)C)C1C(C)C(Br)C(=O)C(=O)OCc1ccc([N+](=O)[O-])cc1.OC[C@H]1C[C@@H](S)CO1>>CC(O)C1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(SC3COC(CO)C3)C(C)C12,,CCN(CC)CC,,C1CCOC1,,test
US04115385,C1CCCNCC1.CC1(C)S[C@@H]2C(N)C(=O)N2C1c1nnn[nH]1.ClCCl>>CC1(C)S[C@@H]2C(N=CN3CCCCCC3)C(=O)N2C1c1nnn[nH]1,,ClCCl,,CCN(CC)CC,C[Si](C)(C)Cl,test
US20160137643A1,CS(=O)(=O)CCN.O=C(O)c1cnc2cncc(Br)c2c1>>CS(=O)(=O)CCNC(=O)c1cnc2cncc(Br)c2c1,CN(C)C=O,ClCCl,,CCN(CC)CC,Cl,test
US20160031903A1,CN.COC(=O)C1(C)CO1>>CNCC(C)(O)C(=O)OC,,CCO,,,,test
US20020120007A1,CC(C)(C)c1ccc(C(=O)Cl)cc1.COc1ccc(NC(=O)c2ccc([N+](=O)[O-])cc2N)cc1>>COc1ccc(NC(=O)c2ccc([N+](=O)[O-])cc2NC(=O)c2ccc(C(C)(C)C)cc2)cc1,,ClCCl,,c1ccncc1,,test
US20040164272A1,C=CC(=O)Cl.C=CC(=O)OCCCCCCOc1ccc(-c2c(N)c3c(c(N)c2C(=O)[O-])C(=O)c2ccccc2C3=O)cc1>>C=CC(=O)Nc1cc(C(=O)Oc2ccc(CCCCCCC)cc2)c(N)c2c1C(=O)c1ccccc1C2=O,CN(C)c1ccncc1,ClCCl,,,,test
US20130190356A1,CC(C)CBr.O=S(=O)(Cc1ccccc1)NCc1ccc(Br)s1>>CC(C)CN(Cc1ccc(Br)s1)S(=O)(=O)Cc1ccccc1,,CC(=O)N(C)C,CCOC(C)=O,O,[H-].[Na+],test
US20110207701A1,CC(C)(C)N.O=C(O)CCc1cccc2c1B(O)OC2>>CC(C)(C)NC(=O)CCc1cccc2c1B(O)OC2,,ClCCl,,O=S(Cl)Cl,,test
US20100227894A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C1CCNC1c1cc([N+](=O)[O-])ccc1SCC>>CCOC(=O)[C@@H]1CCN(C(=O)OC(C)(C)C)[C@H]1c1cc([N+](=O)[O-])ccc1SCC,,C1CCOC1,,CCN(CC)CC,,test
US20040019113A1,CNN.O=C(/C=C/c1ccco1)c1ccc(Oc2ccccc2)cc1>>Cn1nc(-c2ccc(Oc3ccccc3)cc2)cc1-c1ccco1,,CS(C)=O,,CCOC(C)=O,O,test
US20130267493A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCC(CO)CCOc1ccc(Br)cc1>>Cc1ccc(S(=O)(=O)OCC(CO)CCOc2ccc(Br)cc2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20110217311A1,CC(C)(C)OC(=O)N[C@H]1CC[C@H](Oc2cc(F)ccc2[N+](=O)[O-])C1.O=C(O)C(F)(F)F>>N[C@H]1CC[C@H](Oc2cc(F)ccc2[N+](=O)[O-])C1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20060229314A1,COC(=O)c1cc(C)sc1N.O=C(Cl)OC(Cl)(Cl)Cl>>Cc1cc2c(=O)oc(=O)[nH]c2s1,,O,,[K+].[OH-],,test
US20020119983A1,COc1ccccc1N1CCNCC1.O=CCCc1cc(-c2cccc(Oc3ccccc3)c2)no1>>COc1ccccc1N1CCN(CCCc2cc(-c3cccc(Oc4ccccc4)c3)no2)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20080280875A1,BrCc1ccccc1.CC(C)(C)OC(=O)c1cc(O)c2c(c1)OC(CO)C2>>CC(C)(C)OC(=O)c1cc(OCc2ccccc2)c2c(c1)OC(CO)C2,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140213581A1,COC(=O)c1nc2ccc(Cl)cn2c1C>>Cc1c(C(=O)O)nc2ccc(Cl)cn12,,CO,,Cl,[K+].[OH-],test
US20040058820A1,C[C@@H](O)[C@@H](Cc1ccc(Cl)cn1)c1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>C[C@H](N=[N+]=[N-])[C@@H](Cc1ccc(Cl)cn1)c1ccccc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150329506A1,C/C(=N\[S@](=O)C(C)(C)C)c1cc(Br)c(F)cc1F.CC(=O)c1c(C)noc1C>>Cc1noc(C)c1C(=O)C[C@](C)(N[S@](=O)C(C)(C)C)c1cc(Br)c(F)cc1F,,C1CCOC1,,O,[Li]CCCC,test
US05156763,CCCCBr.Oc1cc(F)cc(F)c1>>CCCCOc1cc(F)cc(F)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080153836A1,COC(=O)c1cc(C(C)=O)c(C(F)(F)F)cc1NC(C)=O.COC(OC)N(C)C>>COC(=O)c1cc(C(=O)/C=C/N(C)C)c(C(F)(F)F)cc1NC(C)=O,,CCOC(C)=O,,,,test
US20130012485A1,NCC1(c2cccc(Cl)c2)CCC2(CC1)OCCO2.O=C(OCc1ccccc1)ON1C(=O)CCC1=O>>O=C(NCC1(c2cccc(Cl)c2)CCC2(CC1)OCCO2)OCc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20130123239A1,CC(C)(C)OC(=O)N1CCC(F)(c2ncc(C[C@@H](O)CO)cc2F)CC1>>OC[C@H](O)Cc1cnc(C2(F)CCNCC2)c(F)c1,,C1COCCO1,ClCCl,CCOCC,Cl,test
US20100029605A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNc1cc(Cl)ncn1>>CN(C(=O)OC(C)(C)C)c1cc(Cl)ncn1,,ClCCl,,CCN(CC)CC,CN(C)c1ccccn1,test
US20040181063A1,F.Nc1nc(OCc2ccccc2)c2nccc-2[nH]1.O=C1CCC(=O)N1Br>>Fc1nc(OCc2ccccc2)c2ncc(Br)c-2[nH]1,,C1CCOC1,c1ccncc1,CC(C)(C)ON=O,,test
US06440972B1,O=C(N1CCNCC1)N1CCN(c2ccncc2)CC1.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>O=C(N1CCN(c2ccncc2)CC1)N1CCN(S(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20150329538A1,Cc1ccc(S(=O)(=O)n2ccc(C(=O)OC(C)(C)C)c2[C@@H](CCOCc2ccccc2)NC(=O)OC(C)(C)C)cc1.O=C(O)C(F)(F)F>>Cc1ccc(S(=O)(=O)n2ccc(C(=O)O)c2[C@H](N)CCOCc2ccccc2)cc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20040097509A1,CSc1ccc(S)cc1.O=Cc1cnccc1Cl>>CSc1ccc(Sc2ccncc2C=O)cc1,,CN(C)C=O,,,,test
US20050153971A1,O=C1CCC(=O)N1I.O=C1OC(CO)CN1c1cccc(F)c1>>O=C1O[C@@H](CO)CN1c1ccc(I)c(F)c1,,O=C(O)C(F)(F)F,,,,test
US04259104,NNC(=O)COc1ccc(Cl)cc1Cl.S=C=S>>S=C1N=NC(COc2ccc(Cl)cc2Cl)O1,,CN(C)C=O,,,,test
US04377576,C1COCCN1.CN1C(=O)c2ccccc2N(C(=O)CCCl)c2ccccc21>>CN1C(=O)c2ccccc2N(C(=O)CCN2CCOCC2)c2ccccc21.Cl,,CC(C)O,,,,test
US20120040951A1,CC(O)c1cnc(Nc2ccc(C(F)(F)F)cc2)cn1.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>CC(N=[N+]=[N-])c1cnc(Nc2ccc(C(F)(F)F)cc2)cn1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20020040138A1,CC(C)(C)C(=O)Nc1c(F)cc(Cl)cc1C(=O)C(F)(F)F>>Nc1c(F)cc(Cl)cc1C(=O)C(F)(F)F,,COCCOC,,Cl,O=C([O-])[O-].[K+].[K+],test
US06022906,CC(C)(C(=O)c1ccc(F)cc1)N1CCOCC1.SCCS>>CC(C)(C(=O)c1ccc(SCCS)cc1)N1CCOCC1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20040186132A1,C#CC(C)(C)OC(C)=O.Nc1ccccc1>>C#CC(C)(C)Nc1ccccc1,Cl[Cu],C1CCOC1,,CCN(CC)CC,,test
US20160083362A1,COC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2C[C@@H]2CCN(C(=O)C(F)(F)F)C2)ccc2c1OC[C@@H]1C[C@H]21>>COC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2C[C@@H]2CCNC2)ccc2c1OC[C@@H]1C[C@H]21,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20150051262A1,COC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H](COC(C)=O)NC(=O)OCc1ccccc1)[C@@H](C)O.COC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1>>COC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](NC(=O)OCc1ccccc1)[C@H](C)OC(C)=O,,CN(C)C=O,ClCCl,CN1CCOCC1,,test
US20070105904A1,C#Cc1cccnc1.ON=C(Cl)Cc1ccc(COc2ccccn2)cc1>>c1ccc(OCc2ccc(Cc3cc(-c4cccnc4)on3)cc2)nc1,,C1CCOC1,,CCN(CC)CC,,test
US05843937,COC(=O)C=Cc1cc2cc(NC(=O)c3cc4ccccc4o3)ccc2[nH]1>>O=C(O)C=Cc1cc2cc(NC(=O)c3cc4ccccc4o3)ccc2[nH]1,,CN(C)C=O,,CCO,[Na+].[OH-],test
US20100093733A1,CCOC(=O)C=C1CCC(c2ccc([N+](=O)[O-])cc2)CC1>>CCOC(=O)C[C@@H]1CC[C@@H](c2ccc(N)cc2)CC1,[Pd],,,,,test
US20080009530A1,CCOC(=O)/C=C/c1ccc(O)cc1Oc1ncc(C(F)(F)F)cc1Cl.Clc1ncccn1>>CCOC(=O)/C=C/c1ccc(Oc2ncccn2)cc1Oc1ncc(C(F)(F)F)cc1Cl,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20030144283A1,CCCCc1nc2c(N)nc3ccccc3c2n1CCCCCCCCN.O=C(Cl)c1ccccc1>>CCCCc1nc2c(N)nc3ccccc3c2n1CCCCCCCCNC(=O)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US05034417,CC1(c2ccc([N+](=O)[O-])c(Nc3ccc(F)cc3F)c2)OCCO1>>CC(=O)c1ccc([N+](=O)[O-])c(Nc2ccc(F)cc2F)c1,,CC(C)=O,,Cl,,test
US20120149718A1,CS(=O)(=O)c1ccc(CC(=O)O)cc1.O=C(Cl)C(=O)Cl>>CS(=O)(=O)c1ccc(CC(=O)Cl)cc1,CN(C)C=O,C1CCOC1,ClCCl,,,test
US20100152183A1,CC(C)(C)[Si](C)(C)OC1CCC(=O)CC1.CN(C)C=O.O=P(Cl)(Cl)Cl>>O=CC1=C(Cl)CCC(O)C1,,CCOC(C)=O,,,,test
US20160122307A1,COC(=O)N1CCN[C@@H]2[C@H](O)CCC[C@@H]21.O=S(=O)(Cl)Cl>>COC(=O)N1CCN2[C@@H]3[C@@H](CCC[C@@H]31)OS2(=O)=O,,ClCCl,,CCN(CC)CC,,test
US05089621,BrCc1ccccc1.Cc1ccc(S(=O)(=O)N2CC3=C(CNCC3)C2)cc1>>Cc1ccc(S(=O)(=O)N2CC3=C(C2)C(Cc2ccccc2)NCC3)cc1,,CO,,[Na+].[OH-],,test
US20150210710A1,CC(C)(C)OC(=O)N1CC2(C1)OCc1cc(Br)ccc12.CN(C)C=O>>CC(C)(C)OC(=O)N1CC2(C1)OCc1cc(C=O)ccc12,,C1CCOC1,,[Li]CCCC,,test
US04853469,OCc1csc(=S)n1-c1ccc(F)c(F)c1F>>Fc1ccc2c(c1F)OCc1csc(=S)n1-2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120220590A1,COC(=O)c1cc(OCCc2cccnc2)cc(Oc2ccc(CN(Cc3ccc(C#N)cc3)c3cccc(NS(C)(=O)=O)c3C)cc2)c1>>Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccc(C#N)cc1)Cc1ccc(Oc2cc(OCCc3cccnc3)cc(C(=O)O)c2)cc1,,C1CCOC1,,Cl,[Li+].[OH-],test
US20070124152A1,ClCCBr.O=S1(=O)CCCCN1>>O=S1(=O)CCCCN1CCCl,,CN(C)C=O,,[H-].[Na+],,test
US20100216836A1,CC1(CO)CCN(CC2COc3ccccc3O2)C1.CI>>COCC1(C)CCN(CC2COc3ccccc3O2)C1,,C1CCOC1,,O,[H-].[Na+],test
US04213985,CC(Cl)C(=O)Cl.O=C1Nc2cccnc2Nc2ccccc21>>CC(Cl)C(=O)N1c2ccccc2C(=O)Nc2cccnc21,,C1COCCO1,,,,test
US04383052,C=C(C)C(=O)Cl.CC(O)(P(=O)(O)O)P(=O)(O)O>>C=C(C)C(=O)OC(C)(P(=O)(O)O)P(=O)(O)O,,CCN(CC)CC,,Cl,,test
US20030232790A1,CC(C)S(=O)(=O)Cc1c(O)ccc2c1CCCC2=O.N#Cc1ccc(Cn2cncc2CCO)cc1>>CC(C)S(=O)(=O)Cc1c(OCCc2cncn2Cc2ccc(C#N)cc2)ccc2c1CCCC2=O,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150368269A1,CC(=O)O[C@@H](C(=O)O)[C@H]1OCCN(c2ccn(-c3ccncc3)n2)C1=O.Nc1cc2onc(N3C(=O)c4ccccc4C3=O)c2cc1S(N)(=O)=O>>CC(=O)O[C@@H](C(=O)Nc1cc2onc(N3C(=O)c4ccccc4C3=O)c2cc1S(N)(=O)=O)[C@H]1OCCN(c2ccn(-c3ccncc3)n2)C1=O,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090131467A1,NN.O=C(Cc1ccc(F)cc1)c1c(O)c2cccnc2n(-c2cccc(OC(F)(F)F)c2)c1=O>>O=c1c2c(Cc3ccc(F)cc3)n[nH]c2c2cccnc2n1-c1cccc(OC(F)(F)F)c1,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US20080021087A1,CC[Mg]Cl.Cc1c(C=O)c2c(c(C)c1NC(=O)CC(C)(C)C)C(c1ccc(C(C)C)cc1)CO2>>CCC(O)c1c(C)c(NC(=O)CC(C)(C)C)c(C)c2c1OCC2c1ccc(C(C)C)cc1,,O,,,,test
US20150166564A1,CCOC(=O)c1cnn(-c2ccccc2)c1NC(=O)N[C@@H]1CN(CCOC)C[C@H]1c1ccc(F)c(F)c1>>COCCN1C[C@@H](NC(=O)Nc2c(CO)cnn2-c2ccccc2)[C@H](c2ccc(F)c(F)c2)C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120029026A1,COC(=O)c1cccc(OCc2nc3ccc(O)cc3n2C)c1.Fc1ncc(Br)cc1Br>>COC(=O)c1cccc(OCc2nc3ccc(Oc4ncc(Br)cc4Br)cc3n2C)c1,I[Cu]I,CN(C)C=O,,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US20060094767A1,CC(C)(C)OC(=O)N1CCN(c2ccc(O)cc2Cl)CC1.C[C@@]1(Cn2cc([N+](=O)[O-])nc2Cl)CO1>>CC(C)(C)OC(=O)N1CCN(c2ccc(OC[C@@]3(C)Cn4cc([N+](=O)[O-])nc4O3)cc2Cl)CC1,,CN(C)C=O,,[H-].[Na+],,test
US05204353,CN(C)c1nc(Cl)c2nnn(Cc3ccccc3F)c2n1.CNC>>CN(C)c1nc(N(C)C)c2nnn(Cc3ccccc3F)c2n1,,CCO,,,,test
US05776940,NCC1CC1.O=C(n1ccnc1)n1ccnc1>>O=C(NCC1CC1)NCC1CC1,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20090182023A1,CC(=O)NCCC1CCc2ccc(N)c(O)c21.O=C(Cl)COCc1ccccc1>>CC(=O)NCCC1CCc2ccc(NC(=O)COCc3ccccc3)c(O)c21,,c1ccncc1,,Cl,O,test
US04670447,CN1CCC(c2n[nH]c3ccc([N+](=O)[O-])cc23)CC1.O=C(Cl)c1ccccc1>>CN1CCC(c2nn(C(=O)c3ccccc3)c3ccc([N+](=O)[O-])cc23)CC1.Cl,,CCOCC,,,,test
US06448236B1,CCNC(=O)[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CN)nc32)[C@@H]2OC(C)(C)O[C@@H]21.CS(=O)(=O)Cl>>CCNC(=O)[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CNS(C)(=O)=O)nc32)[C@H](O)[C@@H]1O,,ClCCl,,CCN(CC)CC,,test
US20130324551A1,CN1CCN(c2nc(-c3c(F)ccc(NS(=O)(=O)c4cc(F)ccc4F)c3F)cs2)CC1.O=C1CCC(=O)N1Br>>CN1CCN(c2nc(-c3c(F)ccc(NS(=O)(=O)c4cc(F)ccc4F)c3F)c(Br)s2)CC1,,ClCCl,,,,test
US20050277632A1,CC(C)(Cc1ccc(F)cc1F)NCC(O)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12>>CC(C)(Cc1ccc(F)cc1F)NCC(O)c1ccc(O)c2c1CCC(=O)N2,[Pd],CO,,,,test
US20050032786A1,CC(C)(C)Sc1cccc(C#N)n1.COC(=O)c1ccccc1S>>CC(C)(C)Sc1cccc(-c2nc(=O)c3ccccc3s2)n1,,Cc1ccccc1,,CCN(CC)CC,,test
US06403601B1,COc1cc2c(c(C(=O)O)c1OC)CCCC2.O=C(Cl)C(=O)Cl>>COc1cc2c(c(C(=O)Cl)c1OC)CCCC2,CN(C)C=O,ClCCl,,,,test
US20080064868A1,COc1ccc(C(OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)[C@H](F)[C@@H]2OC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)(c2ccccc2)c2ccc(OC)cc2)cc1>>C[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](F)[C@@H]1O,,CO,,CC(=O)O,,test
US20150291595A1,COc1cccc(B2OC(C)(C)C(C)(C)O2)n1.Cc1ccn2nc([C@H](C)Nc3ncnc4c3c(Br)cn4COCC[Si](C)(C)C)n(-c3ccccc3)c(=O)c12>>COc1cccc(-c2cn(COCC[Si](C)(C)C)c3ncnc(N[C@@H](C)c4nn5ccc(C)c5c(=O)n4-c4ccccc4)c23)n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US04797401,CC(=O)N1CCN(c2ccc(N)c(C)c2)CC1.CS(=O)(=O)Cl>>CC(=O)N1CCN(c2ccc(NS(C)(=O)=O)c(C)c2)CC1,,c1ccncc1,,,,test
US20020040020A1,CC(C)(C)OC(=O)N1CCNCC1.O=[N+]([O-])c1cccc([N+](=O)[O-])c1Cl>>CC(C)(C)OC(=O)N1CCN(c2c([N+](=O)[O-])cccc2[N+](=O)[O-])CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US03962255,CC(C)CC(=O)NCC(C)(C)N.CC(C)COC(=O)Cl>>CC(C)COC(=O)N(CC(C)(C)N)C(=O)CC(C)C,,Cc1ccccc1,,,,test
US20060069123A1,O=C1COc2ncccc21.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>O=S(=O)(Oc1coc2ncccc12)C(F)(F)F,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20090176804A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Clc1cccc2[nH]ccc12>>CC(C)(C)OC(=O)n1ccc2c(Cl)cccc21,CN(C)c1ccncc1,ClCCl,,,,test
US20110213143A1,CCCC(=O)OC(OC(=O)Oc1ccc([N+](=O)[O-])cc1)C(C)C.NCCC[C@@H](Cc1ncn2c1CCc1ccccc1-2)C(=O)O>>CCCC(=O)OC(OC(=O)NCCC[C@@H](Cc1ncn2c1CCc1ccccc1-2)C(=O)O)C(C)C,,CN(C)C=O,,O,,test
US20150259323A1,CCOC(=O)c1cnc(Cl)nc1.CCOc1ccccc1O[C@@H]1CCCNC1>>CCOC(=O)c1cnc(N2CCC[C@@H](Oc3ccccc3OCC)C2)nc1,,CS(C)=O,O,CCN(CC)CC,,test
US20110015178A1,CCCC[Sn](CCCC)(CCCC)c1ccccn1.O=C(c1csc(Br)c1)N1CCCCC1>>O=C(c1csc(-c2ccccn2)c1)N1CCCCC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,,,,test
US20120202785A1,CC(C)(C)OC(=O)N[C@H]1CCCN(CCOC(=O)C(C)(C)C)C1>>CC(C)(C)C(=O)OCCN1CCC[C@H](N)C1,,ClCCl,,Cc1ccccc1,O=C(O)C(F)(F)F,test
US04179505,CNc1ccc(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1[N+](=O)[O-]>>CNc1ccc(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1N,[Ni],CO,,[H][H],,test
US20030065187A1,Cc1ccc(Br)cc1.N[C@@H]1CCCC[C@H]1N>>Cc1ccc(N[C@@H]2CCCC[C@H]2N)cc1,[Cu]I,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20120100161A1,CC[C@H](C)[C@@H]1NC(=O)CNC(=O)[C@@H]2Cc3c([nH]c4cc(O)ccc34)[S+]([O-])C[C@@H](NC(=O)CNC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H]([C@@H](C)[C@@H](O)CO)C(=O)N2.O=C1CCCC(=O)O1.O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3>>CC[C@H](C)[C@@H]1NC(=O)CNC(=O)[C@@H]2Cc3c([nH]c4cc(O)ccc34)[S+]([O-])C[C@@H](NC(=O)CNC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H]([C@@H](C)[C@@H](O)CO)C(=O)N2.O=C([O-])CCCC(=O)[O-],,c1ccncc1,,,,test
US20070213331A1,CCCN(C)C(=O)c1cc(C(=O)OCC)cc(C(=O)OCC)c1>>CCCN(C)C(=O)c1cc(C(=O)O)cc(C(=O)OCC)c1,,CCO,,Cl,[Na+].[OH-],test
US20130336920A1,Cc1cccc(CN)c1.O=[N+]([O-])c1ccc(N2CCCCC2)cc1-c1cc(Cl)ncn1>>Cc1cccc(CNc2cc(-c3cc(N4CCCCC4)ccc3[N+](=O)[O-])ncn2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06479505B1,COc1ccc([C@@H]2CCCC[C@@H]2N)cc1OC.O=C(Cl)c1ccc2c(c1)OCO2>>COc1ccc([C@H]2CCCC[C@H]2NC(=O)c2ccc3c(c2)OCO3)cc1OC,,CCN(CC)CC,ClCCl,,,test
US05744479,Cc1c(-c2ccc([N+](=O)[O-])cc2)sc2c1c(=O)c(S(=O)C(C)C)cn2Cc1c(F)cccc1F.O=C1CCC(=O)N1Br>>CC(C)S(=O)c1cn(Cc2c(F)cccc2F)c2sc(-c3ccc([N+](=O)[O-])cc3)c(CBr)c2c1=O,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US04931444,COc1ccc(N2CCN(c3ccc(NC(=S)NCC(OC)OC)cc3)CC2)cc1>>COc1ccc(N2CCN(c3ccc(NC4=NCC(OC)S4)cc3)CC2)cc1,,O=CO,,,,test
US05654297,Cc1c(F)cccc1C(=O)Cl.Nc1ccc(C(=O)N2CCCC(=O)c3sccc32)cc1>>Cc1c(F)cccc1C(=O)Nc1ccc(C(=O)N2CCCC(=O)c3sccc32)cc1,,ClCCl,,CCN(CC)CC,,test
US04879295,COc1ccccc1-c1nc(C(=O)O)cs1.Nc1nnn[nH]1>>COc1ccccc1-c1nc(C(=O)Nc2nnn[nH]2)cs1,,CN(C)C=O,,,,test
US06936608B2,CC1(C)OB(c2ccc(F)c(-c3ccccc3C#N)c2)OC1(C)C.FC(F)(F)c1cnn2c(Br)cnc2n1>>N#Cc1ccccc1-c1cc(-c2cnc3nc(C(F)(F)F)cnn23)ccc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(=O)N(C)C,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20020032227A1,CON=C(c1cc(C)no1)c1ccccc1CO.FC(F)(F)c1cnc(Cl)c(Cl)c1>>CON=C(c1cc(C)no1)c1ccccc1COc1ncc(C(F)(F)F)cc1Cl,,O,,C1CCOC1,[H-].[Na+],test
US20100305102A1,C1CNCCN1.Cn1c(Cl)nc2cc(F)ccc21>>Cn1c(N2CCNCC2)nc2cc(F)ccc21,,CCCCO,,,,test
US04528382,CN=C(Cl)c1ccc(C)cc1.COC(=O)Cc1cccn1C.O=S(=O)(O)Cl>>COC(=O)Cc1ccc(C(=O)c2ccc(C)cc2)n1C,,O,,CC(=O)[O-].[Na+],,test
US05840732,CCC(O)C(=O)O.CCO.O=C1CSC(=O)N1CCCCSc1cccc2nccn12>>CCOC(=O)C=C1SC(=O)N(CCCCSc2cccc3nccn23)C1=O,,CCO,,C1CCNCC1,,test
US20080269208A1,COC(=O)[C@H]1NCC[C@@H]1O.O=C(Cl)CCl>>COC(=O)[C@@H]1[C@@H](O)CCN1C(=O)CCl,,c1ccccc1,,CCN(CC)CC,Cl,test
US20080262040A1,CC(C)(C)C1CC(n2ncc3c(C(N)=O)cc(-c4ccccc4)cc32)CCN1C(=O)[O-]>>NC(=O)c1cc(-c2ccccc2)cc2c1cnn2C1CCNCC1,,CO,,Cl,,test
US20050009843A1,CC(C)(C)OC(=O)/C=C/c1c(N2CCC[C@@H](O)C2)nc2cc(C(=O)Nc3nc(C(C)(C)C)cs3)ccn2c1=O.O=C=NCCCl>>CC(C)(C)OC(=O)/C=C/c1c(N2CCC[C@@H](OC(=O)NCCCl)C2)nc2cc(C(=O)Nc3nc(C(C)(C)C)cs3)ccn2c1=O,,O,,ClCCl,c1ccncc1,test
US20090111808A1,ClCCCN1CCCCC1.[O-][n+]1ccc(-c2ccc(O)cc2)cc1>>[O-][n+]1ccc(-c2ccc(OCCCN3CCCCC3)cc2)cc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20120309796A1,CC(C)(C)OC(=O)COc1cccc2c1CCCCC2NS(=O)(=O)c1ccc(I)cc1.CSc1cccc(B(O)O)c1>>CSc1cccc(-c2ccc(S(=O)(=O)NC3CCCCc4c(OCC(=O)OC(C)(C)C)cccc43)cc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20110224274A1,CCCN1C(=O)c2ccccc2C1(O)c1ccc(Cl)cc1.O=S(Cl)Cl>>CCCN1C(=O)c2ccccc2C1(Cl)c1ccc(Cl)cc1,CN(C)C=O,,,,,test
US20130261178A1,CC(C)OCCOc1ccc(O)cc1.ClCC1CO1>>CC(C)OCCOc1ccc(OCC2CO2)cc1,,O,,[Na+].[OH-],,test
US20080207691A1,CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@@H](N2CCCCC2=O)CC1>>O=C1CCCCN1[C@@H]1CC[C@@H](O)CC1,,CCO,,,,test
US20030203896A1,CCOC(=O)CCCBr.Cc1nc(Cl)c2cc[nH]c2n1>>CCOC(=O)CCCn1ccc2c(Cl)nc(C)nc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080293776A1,C=Cc1ccc(N2CC(=O)N(CC[Si](C)(C)C)S2(=O)=O)c(OCc2ccccc2)c1.O=[Os](=O)(=O)=O>>C[Si](C)(C)CCN1C(=O)CN(c2ccc(C=O)cc2OCc2ccccc2)S1(=O)=O,O=[Os](=O)(=O)=O,CC(C)(C)O,O,C1CCOC1,O=C([O-])O.[Na+],test
US20060217380A1,CC(C)(C)[Si](C)(C)O[C@@H]1CCCN(c2ccc(C(F)(F)F)cc2NC(=O)c2cc(C#Cc3cnc(N)nc3)ccc2F)C1>>Nc1ncc(C#Cc2ccc(F)c(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCC[C@@H](O)C3)c2)cn1,,CCOC(C)=O,,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05635510,CCOC(=O)CC1(c2ccc(OC)c(OC)c2)CNC(=O)C1>>COc1ccc(C2(CCO)CCNC2)cc1OC,,C1CCOC1,ClCCl,O,[Na+].[OH-],test
US20100009950A1,CC1(C)OCc2cc(C(=O)CBr)ccc2O1.[N-]=[N+]=[N-]>>CC1(C)OCc2cc(C(=O)CN=[N+]=[N-])ccc2O1,,CN(C)C=O,,CCOC(C)=O,O,test
US05977119,O=c1[nH]c(=O)c2[nH]cnc2[nH]1.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>O=c1[nH]c(=S)c2[nH]cnc2[nH]1,,c1ccncc1,,[Na+].[OH-],,test
US20020165221A1,COC(=O)[C@@H]1C[C@H](N(Cc2cccc(OC)c2)C(=O)CC(C)(C)C)CN1.O=Cc1ccc2c(c1)OCO2>>COC(=O)[C@@H]1C[C@H](N(Cc2cccc(OC)c2)C(=O)CC(C)(C)C)CN1Cc1ccc2c(c1)OCO2,,C1CCOC1,,CC(=O)O,[BH3-]C#N.[Na+],test
US20080255086A1,NC(=O)c1c(N)sc2c1CCCC2.O=C(Cl)CCCl>>NC(=O)c1c(NC(=O)CCCl)sc2c1CCCC2,,ClCCl,,CCN(CC)CC,Cl,test
US20070249670A1,CCCCNCC(=O)OCc1ccccc1.Nc1cc2ccccc2cc1C(=O)O>>CCCCN(CC(=O)OCc1ccccc1)C(=O)c1cc2ccccc2cc1N,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05185350,COC(=O)Cl.Cn1ccc2cc(Nc3ccncc3)ccc21>>COC(=O)N(c1ccncc1)c1ccc2c(ccn2C)c1,,CCN(CC)CC,ClCCl,,,test
US06218376B1,COC(=O)C=CC=Cc1cccc(OC)c1>>COc1cccc(C=CC=CC(=O)O)c1,,CO,O,[Li+].[OH-],,test
US20150132342A1,CCOC(=O)c1nc(Nc2cc(Oc3ccccc3)cc([N+](=O)[O-])c2)c2ccccc2n1>>CCOC(=O)c1nc(Nc2cc(N)cc(Oc3ccccc3)c2)c2ccccc2n1,[Ni],CCO,,,,test
US04410548,COc1cc(SC#N)ccc1O>>COc1cc(SC)ccc1O,,CO,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20080039457A1,COC(=O)c1ccc(-c2cnc3nnc(C4(c5ccc6ncccc6c5)CC4)n3n2)cc1.NCC1CC1>>O=C(NCC1CC1)c1ccc(-c2cnc3nnc(C4(c5ccc6ncccc6c5)CC4)n3n2)cc1,,CO,Cc1ccccc1,C[Al](C)C,,test
US04105652,CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](COCc1ccccc1)NC(=O)OC(C)(C)C)[C@@H](C)OCc1ccccc1)C(=O)N[C@H](C(=O)N[C@H](C(=O)OCc1ccccc1)[C@@H](C)OCc1ccccc1)C(C)C.NN>>CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](COCc1ccccc1)NC(=O)OC(C)(C)C)[C@@H](C)OCc1ccccc1)C(=O)N[C@H](C(=O)N[C@H](C(=O)NN)[C@@H](C)OCc1ccccc1)C(C)C,,CN(C)C=O,CO,,,test
US03931173,Cc1ccc(O)c(Cc2cc(C)ccc2O)c1.O=C(O)C(Cl)Cl>>Cc1ccc2c(c1)Cc1cc(C)ccc1OC(C(=O)O)O2,,CC(C)O,,O=C([O-])[O-].[K+].[K+],,test
US20060223819A1,C=CS(C)(=O)=O.C[C@H](NC(=O)c1c(CN2CCNCC2)c(-c2ccccc2)nc2ccccc12)C1CCCCC1>>C[C@H](NC(=O)c1c(CN2CCN(CCS(C)(=O)=O)CC2)c(-c2ccccc2)nc2ccccc12)C1CCCCC1,,CC(C)O,,,,test
US20140179680A1,CO.C[C@@H]1CC[C@@H](Cn2c(N3CCC[C@H]3CF)nc3cc(C#N)nc(-c4cncc(Cl)c4)c32)CC1>>COC(=N)c1cc2nc(N3CCC[C@H]3CF)n(C[C@@H]3CC[C@@H](C)CC3)c2c(-c2cncc(Cl)c2)n1,,CO,,C[O-].[Na+],,test
US20080269286A1,FC(F)(F)c1cc(C2=CCNCC2)ccc1Cl>>FC(F)(F)c1cc(C2CCNCC2)ccc1Cl,O=[Pt],CO,,Cl,,test
US04317820,CCOC=C(C(=O)[O-])C(=O)OCC.Clc1cc(Cl)c2c(c1)NCCC2>>O=C(O)c1cn2c3c(c(Cl)cc(Cl)c3c1=O)CCC2,,O,,CCO,[Na+].[OH-],test
US20120225812A1,Cc1ncccc1Oc1nc2nc(C3CCCC3)n(COCC[Si](C)(C)C)c2c(=O)n1CC(C)C>>Cc1ncccc1Oc1nc2nc(C3CCCC3)[nH]c2c(=O)n1CC(C)C,,CCO,,Cl,,test
US20140249104A1,Cc1cccc([C@](CF)(CC(=O)C(F)(F)F)N[S@](=O)C(C)(C)C)c1F>>Cc1cccc([C@](CF)(C[C@H](O)C(F)(F)F)N[S@](=O)C(C)(C)C)c1F,,CC(C)O,,,,test
US20060025432A1,CC(C)(C)[Si](C)(C)Cl.C[C@H](CO)Nc1cc(N)nc(SCc2ccccc2)n1>>C[C@H](CO[Si](C)(C)C(C)(C)C)Nc1cc(N)nc(SCc2ccccc2)n1,,CN(C)C=O,,c1c[nH]cn1,,test
US07538242B2,CCCCOC(=O)[C@H](CC)OS(=O)(=O)C(F)(F)F.O=Cc1cccc(O)c1>>CCCCOC(=O)[C@@H](CC)Oc1cccc(C=O)c1,,CC#N,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20130045942A1,NO.O=Cc1ccc(OC(F)(F)F)cc1>>ON=Cc1ccc(OC(F)(F)F)cc1,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20040235891A1,COc1ccc(CCN)cc1OC.O=CCC(c1ccccc1)c1ccccc1>>COc1cc2c(cc1OC)C(CC(c1ccccc1)c1ccccc1)NCC2,,O=CO,,,,test
US20030087925A1,CCC1CCC(N)C(c2ccccc2)N1.O=C(O)C(O)(C(=O)c1ccccc1)C(O)(C(=O)O)C(=O)c1ccccc1>>CC[C@H]1CC[C@H](N)[C@H](c2ccccc2)N1.O=C(O)[C@@](O)(C(=O)c1ccccc1)[C@@](O)(C(=O)O)C(=O)c1ccccc1,,CC(C)O,O,,,test
US20120035372A1,CCCC[Mg]Cl.FC(F)(F)c1cc(Cl)nc(Cl)c1>>CCCCc1cc(C(F)(F)F)cc(Cl)n1,Cl[Fe](Cl)Cl,O,,C1CCOC1,,test
US20070149577A1,COc1ncc(C#N)cc1-c1ccc(CN)cc1.O=S(=O)(Cl)c1ccccc1OC(F)(F)F>>COc1ncc(C#N)cc1-c1ccc(CNS(=O)(=O)c2ccccc2OC(F)(F)F)cc1,,ClCCl,,CCN(CC)CC,,test
US20140378446A1,COC(=O)/C=C/CN(C)C(=O)OC(C)(C)C>>CN(C/C=C/C(=O)O)C(=O)OC(C)(C)C,,C1CCOC1,O,[Li+].[OH-],,test
US06838576B1,CCCBr.CCCP(CCC)CCC>>CCC[P+](CCC)(CCC)CCC.[Br-],,CC#N,,,,test
US20040235915A1,CCC(=O)NC.COc1ccc(C2COCCOC2)c2sc(NC(=O)c3ccc(CCl)cc3)nc12>>CCC(=O)N(C)Cc1ccc(C(=O)Nc2nc3c(OC)ccc(C4COCCOC4)c3s2)cc1,,O,,[H-].[Na+],,test
US20120015943A1,CCOC(=O)c1ccc2c(c1)CCC[C@H]2N[S@](=O)C(C)(C)C.Cl>>CCOC(=O)c1ccc2c(c1)CCC[C@H]2N.Cl,,CO,,C1COCCO1,,test
US20060025445A1,CC(C)(N)C(=O)c1ccccc1.CCCc1ccc(S(=O)(=O)Cl)cc1>>CCCS(=O)(=O)NC(C)(C)C(=O)c1ccccc1,,CN(C)C=O,,CCN(CC)CC,Cc1ccc(S(=O)(=O)O)cc1,test
US20150065343A1,CCOC(=O)c1sc(/C=C/C(=O)OC(C)(C)C)cc1C>>CCOC(=O)c1sc(/C=C/C(=O)O)cc1C,,CCOC(C)=O,,Cl,,test
US05403854,CCOc1c(OCC)c(=O)c1=O.N#Cc1ccc(N)cc1>>CCOc1c(Nc2ccc(C#N)cc2)c(=O)c1=O,,CCO,,,,test
US20150291533A1,COC(=O)C1(C)CCN(S(=O)(=O)c2ccc(C)cc2)c2ccccc2C1>>COC(=O)C1(C)CCNc2ccccc2C1,,CO,,[Mg],[Cl-].[NH4+],test
US20150099736A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN1CCN(c2ccc3[nH]ccc3c2)CC1>>CN1CCN(c2ccc3c(ccn3C(=O)OC(C)(C)C)c2)CC1,CN(C)c1ccncc1,ClCCl,,,,test
US20120058989A1,CCOC(=O)c1cn(C2CC2)c2c(CO)c(N[C@H](CO)CCC(=O)OC(C)(C)C)c(F)cc2c1=O>>CCOC(=O)c1cn(C2CC2)c2c3c(c(F)cc2c1=O)N[C@@H](CCC(=O)O)COC3,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130123250A1,Cc1cc(F)ccc1[C@H]1C[C@]2(CC[C@H](C(N)=O)N2)CCN1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1.Cl>>Cc1cc(F)ccc1[C@H]1C[C@]2(CC[C@H](C(N)=O)N2)CCN1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1.Cl,,CCOCC,CCOCC,,,test
US04766133,CO.Cc1cccnc1CSc1nc2ccc(C(F)(F)F)cc2[nH]1>>Cc1cccnc1CS(=O)c1nc2ccc(C(F)(F)F)cc2[nH]1,,ClCCl,,,,test
US20130059834A1,Cn1nc(-c2cnc3c(n2)c(C(=O)N[C@@H]2CCN(CC#N)C2)cn3COCC[Si](C)(C)C)c2ccc(F)cc21>>Cn1nc(-c2cnc3[nH]cc(C(=O)N[C@@H]4CCN(CC#N)C4)c3n2)c2ccc(F)cc21,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090012118A1,O=C(O)c1cc(=O)c2cc3[nH]c(=O)oc3cc2[nH]1.c1ccc(CC2CCNCC2)cc1>>O=C(c1cc(=O)c2cc3[nH]c(=O)oc3cc2[nH]1)N1CCC(Cc2ccccc2)CC1,,CCOCC,,,,test
US20110294812A1,C=Cc1ccc(NC(=O)OC(C)(C)C)c2ccccc12.OO>>CC(C)(C)OC(=O)Nc1ccc(CCO)c2ccccc12,,C1CCOC1,O,B1C2CCCC1CCC2,[Na+].[OH-],test
US20030096841A1,N#Cc1cccc2c1CN(C(CCC(N)=O)C(=O)O)C2=O>>N#Cc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O,,CC#N,,,,test
US04349568,Cc1cc(Cl)ccc1S(C)(=O)=O.Oc1ccc(Cl)c(Cl)c1>>Cc1cc(Oc2ccc(Cl)c(Cl)c2)ccc1S(C)(=O)=O,,O=S1(=O)CCCC1,,O=C([O-])[O-].[K+].[K+],,test
US20080318981A1,C[Mg]Br.N#Cc1ccc(Cl)cn1.O=C([O-])O>>CC(=O)c1ccc(Cl)cn1,,C1CCOC1,CCOCC,Cl,,test
US20140194406A1,COc1cc(N2CCN(C)CC2)ccc1C#C[Si](C)(C)C>>C#Cc1ccc(N2CCN(C)CC2)cc1OC,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20150119379A1,C=CC(=O)Cl.COc1cc(N(C)CCN(C)C)c(N)cc1Nc1ncc(Cl)c(-c2c[nH]c3ccccc23)n1>>C=CC(=O)Nc1cc(Nc2ncc(Cl)c(-c3c[nH]c4ccccc34)n2)c(OC)cc1N(C)CCN(C)C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090306066A1,CC1(C)CN(c2nc(Cl)nc(NNC(=O)[C@H](CC3CCCC3)CN(C=O)OC3CCCCO3)c2F)C[C@H]1O>>CC1(C)CN(c2nc(Cl)nc(NNC(=O)[C@H](CC3CCCC3)CN(O)C=O)c2F)C[C@H]1O,,CC(=O)O,O,,,test
US20140155391A1,COC(=O)c1ccc(CNS(C)(=O)=O)cc1.Cl.ClCCN1CCOCC1>>CS(=O)(=O)N(CC[NH+]1CCOCC1)Cc1ccc(C(=O)O)cc1.[Cl-],,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US05773530,CC(C)(C)OC(=O)CC1=C(n2nc(-c3c(-c4ccccc4)nn4ccccc34)ccc2=O)CCCC1>>O=C(O)CC1=C(n2nc(-c3c(-c4ccccc4)nn4ccccc34)ccc2=O)CCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090018180A1,CSC1=NCCN1.Cc1ccc(NN)cc1Cl>>Cc1ccc(NNC2=NCCN2)cc1Cl,,Cc1ccccc1C,,I,,test
US20100113462A1,C#CCBr.CCOC(=O)C1(NC(=O)c2cccc(C)c2O)Cc2ccccc2C1>>C#CCOc1c(C)cccc1C(=O)NC1(C(=O)OCC)Cc2ccccc2C1,,CN(C)C=O,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20090156612A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ncn([C@@H]3CCCCC[C@H]3O)c2-c2ccccc2)[C@H](Cc2ccccc2)C1.O=C(O)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ncn([C@@H]3CCCCC[C@@H]3OC(=O)c3ccc([N+](=O)[O-])cc3)c2-c2ccccc2)[C@H](Cc2ccccc2)C1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20160122358A1,COC1(OC)CC(CO)(C(=O)OC(C)C)C1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC1(OC)CC(COS(=O)(=O)C(F)(F)F)(C(=O)OC(C)C)C1,,ClCCl,,Cc1cccc(C)n1,,test
US20020133023A1,COC(=O)CCCCN(C(=O)OC(C)(C)C)c1ccccn1>>CC(C)(C)OC(=O)N(CCCCC(=O)O)c1ccccn1,,CO,O,Cl,[Na+].[OH-],test
US20020165241A1,Clc1cnnc(Cl)c1Cl.NCC1CCN(C(=O)OCc2ccccc2)CC1>>O=C(OCc1ccccc1)N1CCC(CNc2cnnc(Cl)c2Cl)CC1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20090018132A1,CC(OCC1(c2ccc(F)cc2)CCN(C(=O)OC(C)(C)C)CC1)c1cc(N(C)C)cc2cn(COCC[Si](C)(C)C)nc12>>CC(OCC1(c2ccc(F)cc2)CCNCC1)c1cc(N(C)C)cc2c[nH]nc12,,O=C(O)C(F)(F)F,,,,test
US20100267666A1,CCOC(=O)c1c(C)n(COCC[Si](C)(C)C)c2ncc(-c3cc(OC)c(OC)c(OC)c3)nc12>>COc1cc(-c2cnc3c(n2)c(C(=O)O)c(C)n3COCC[Si](C)(C)C)cc(OC)c1OC,,C1CCOC1,,Cl,[Na+].[OH-],test
US04940710,CC(=O)Cl.O=S(=O)(c1ccccc1)n1cccc1>>CC(=O)c1ccn(S(=O)(=O)c2ccccc2)c1,,CC(Cl)Cl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20040224420A1,O=[N+]([O-])c1ccc(Cl)cc1CN(Cc1ccccn1)Cc1ccccn1>>Nc1ccc(Cl)cc1CN(Cc1ccccn1)Cc1ccccn1,[Pd],CO,,,,test
US20080021217A1,COc1cccc(C(=O)Cl)c1.NCc1nc(-c2c[nH]c3ncccc23)cs1>>COc1cccc(C(=O)NCc2nc(-c3c[nH]c4ncccc34)cs2)c1,,ClCCl,,CCN(CC)CC,,test
US20110098276A1,O=C1c2ccccc2C(=O)N1O.O=S(=O)(c1cccc(C(F)(F)F)c1)N1CCC(O)CC1>>O=C1c2ccccc2C(=O)N1OC1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050176751A1,BrCc1ccco1.CC(C)(C)OC(=O)N1CCC(c2c[nH]c3ncccc23)CC1>>c1coc(Cn2cc(C3CCNCC3)c3cccnc32)c1,,CCOCC,,,,test
US05686482,CC(C)I.COC(=O)c1ccc(O)cc1O>>COC(=O)c1ccc(OC(C)C)cc1O,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US04826868,COc1ccc(NN)cc1.O=C(CCCO)CC(=O)c1ccc(Cl)cc1>>COc1ccc(-n2nc(CCCO)cc2-c2ccc(Cl)cc2)cc1,,CO,,Cl,c1ccncc1,test
US20130102776A1,C1N2CN3CN1CN(C2)C3.Cc1ccc2cc[nH]c2n1.O>>Cc1ccc2c(C=O)c[nH]c2n1,,O,,CC(=O)O,,test
US20130302416A1,CCc1cccc(CC)c1NC(=O)c1nn(C)c2c1CCCc1cnc(Nc3ccc(C(=O)OC(C)(C)C)cc3OC)nc1-2.O=C(O)C(F)(F)F>>CCc1cccc(CC)c1NC(=O)c1nn(C)c2c1CCCc1cnc(Nc3ccc(C(=O)O)cc3OC)nc1-2.O=C(O)C(F)(F)F,,ClCCl,,,,test
US04329518,CCc1c(Cl)cccc1-c1ccccc1.N#C[Cu]C#N>>CCc1c(C#N)cccc1-c1ccccc1,,ClCCl,,c1ccncc1,,test
US20150344466A1,CCOC(=O)c1ncc(CCl)s1.OCc1ccccc1>>O=C(O)c1ncc(COCc2ccccc2)s1,,CS(C)=O,,O,[K+].[OH-],test
US20050096380A1,CC(C)Oc1c(C=O)cc2c(c1Cl)OC(C)(C)C=C2C(C)C.C[Mg]Cl>>CC(C)Oc1c(C(C)O)cc2c(c1Cl)OC(C)(C)C=C2C(C)C,,C1CCOC1,,,,test
US20150361098A1,CS(=O)(=O)OCF.Nc1nc2c(O)cccc2c2nc(CCN3Cc4cccnc4C3)nn12>>Nc1nc2c(OCF)cccc2c2nc(CCN3Cc4cccnc4C3)nn12,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040181064A1,Cc1c(N2C(=O)N3CC[C@H](O[Si](C)(C)C(C)(C)C)[C@H]3[C@H]2C)ccc(C#N)c1Cl>>Cc1c(N2C(=O)N3CC[C@@H](O)[C@H]3[C@@H]2C)ccc(C#N)c1Cl,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100009956A1,CC(C)(C)OC(=O)NNC1CCCC1.Clc1ncc(Br)c(Cl)n1>>CC(C)(C)OC(=O)NN(c1nc(Cl)ncc1Br)C1CCCC1,,CCO,,CCN(C(C)C)C(C)C,,test
US03954757,Cc1cc2ccccc2[nH]1.II.S=C1NCCN1>>Cc1[nH]c2ccccc2c1SC1=NCCN1.I,,CO,O,[I-].[K+],,test
US20040176433A1,CC(C)=O.FC(F)(F)c1ccc(-c2n[nH]c(C3CCNCC3)c2-c2ccncc2)cc1>>CC(C)N1CCC(c2[nH]nc(-c3ccc(C(F)(F)F)cc3)c2-c2ccncc2)CC1,,CC(C)=O,,CC(=O)O,[Na+].[OH-],test
US20070219198A1,C=C(Br)C(F)(F)F.C[C@@H]1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1cccc(B2OC(C)(C)C(C)(C)O2)c1>>C=C(c1cccc(S(=O)(=O)N2CCN(c3ccc(F)cc3C(F)(F)F)C[C@H]2C)c1)C(F)(F)F,[Pd],C1CCOC1,CCOCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,O=C([O-])[O-].[Na+].[Na+],test
US20140378446A1,C=O.COC(=O)/C=C/CN[C@H]1CCOC1>>COC(=O)/C=C/CN(C)[C@H]1CCOC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05179212,Cc1ccc(S(=O)(=O)OCC(O)CC#N)cc1.Cl>>Cc1ccc(S(=O)(=O)OCC(O)CCN)cc1.Cl,[Pd],CO,,[H][H],,test
US20060122065A1,C#CCBr.CCOC(=O)CCc1ccc(O)c(OC)c1>>C#CCOc1ccc(CCC(=O)OCC)cc1OC,,CCOC(C)=O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20040147529A1,OCCBr.Oc1ccc(F)cc1F>>OCCOc1ccc(F)cc1F,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20120129851A1,CN(C)C=O.O=C(Nc1ccc(C(=O)O)cc1)Nc1ccc(Br)cc1F>>CN(C)C(=O)c1ccc(NC(=O)Nc2ccc(Br)cc2F)cc1,,O,,ClCCCl,On1nnc2ccccc21,test
US20080255200A1,C1CCOC1.CCN(CC)C(C)C.Nc1ccc(F)cc1[N+](=O)[O-]>>CN(C)c1ccccn1,,C1CCOC1,,CC(=O)OC(C)=O,,test
US04734496,O=C1N[C@H](N2C(=O)c3ccccc3C2=O)[C@@H]1NC(c1ccccc1)(c1ccccc1)c1ccccc1>>N[C@@H]1C(=O)N[C@@H]1N1C(=O)c2ccccc2C1=O,,ClC(Cl)Cl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04144344,COc1ccc(N2CCN(C3CCNCC3)C2=O)cc1.COc1ccccc1OCC1CO1.Cl>>COc1ccc(N2CCN(C3CCN(CC(O)COc4ccccc4OC)CC3)C2=O)cc1.Cl,,CC(C)O,,,,test
US20030036557A1,CS(=O)(=O)c1ccc(N2CC(O)(C(F)(F)F)N=C2c2ccccc2)cc1>>CS(=O)(=O)c1ccc(-n2cc(C(F)(F)F)nc2-c2ccccc2)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20140154179A1,C=C(C)c1cnc(C(=O)N[C@H]2CCN(c3nccn4cccc34)C2)nc1>>CC(C)c1cnc(C(=O)N[C@H]2CCN(c3nccn4cccc34)C2)nc1,[Pd],CO,,,,test
US20050131017A1,O=Cc1csc(-c2cccnc2)n1>>OCc1csc(-c2cccnc2)n1,,C1CCOC1,CO,[BH4-].[Na+],,test
US20060025423A1,O=S(=O)(Nc1ncc(Cl)nc1Cl)c1cccc(Cl)c1Cl.OCc1cccc(CO)n1>>O=S(=O)(Nc1ncc(Cl)nc1OCc1cccc(CO)n1)c1cccc(Cl)c1Cl,,CN1CCCC1=O,,,,test
US20090069408A1,COC(=O)c1cc(C(C)(C)C)cc2c1Oc1c(C(=O)OC)cc(C(C)(C)C)cc1C2(C)C>>CC(C)(C)c1cc(CO)c2c(c1)C(C)(C)c1cc(C(C)(C)C)cc(CO)c1O2,,C1CCOC1,CCOCC,[H-].[Na+],,test
US20100286123A1,COc1c(C#N)ccc2c1CCOC2CN1CCN(C(=O)[O-])C(C(C)(C)C)C1>>COc1c(C#N)ccc2c1CCOC2CN1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05545643,COc1cccc2c1OC(CO)CC2.O=C1NC(=O)c2ccccc21>>COc1cccc2c1OC(CN1C(=O)c3ccccc3C1=O)CC2,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130172325A1,c1ccc(CN2CCN(c3ncnc4[nH]ccc34)CCC23CC3)cc1>>c1nc(N2CCNC3(CC2)CC3)c2cc[nH]c2n1,[Pd],CC(=O)O,CO,,,test
US20130109696A1,COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc(F)c(C#N)c2)c(OC)c1.COc1ccc(S)cc1>>COc1ccc(Sc2ccc(S(=O)(=O)N(Cc3ccc(OC)cc3OC)c3ncns3)cc2C#N)cc1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20130137680A1,O=C(Nc1cccc(-c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)c1)c1ccc2cc3n(c2n1)CCCNC3=O>>O=C(Nc1cccc(-c2c[nH]cn2)c1)c1ccc2cc3n(c2n1)CCCNC3=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100056502A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1ccc(CN2CCOC(CNCc3cc4c(cn3)OCCO4)C2)cc1>>CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)CC1CN(Cc2ccccc2)CCO1,,ClCCl,,,,test
US20080275029A1,COc1ccc(Cn2cnc3cc(NCC4(c5ccc(Cl)cc5)CCN(C(=O)OC(C)(C)C)CC4)ccc3c2=O)c(OC)c1>>O=c1[nH]cnc2cc(NCC3(c4ccc(Cl)cc4)CCNCC3)ccc12,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20040260088A1,Cc1ccc(C#N)c([N+](=O)[O-])c1.O=Cc1cccc(O)c1>>Cc1ccc(C#N)c(Oc2cccc(C=O)c2)c1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20070004710A1,CCOC(=O)COc1ccc(C=O)cc1[N+](=O)[O-]>>O=Cc1ccc2c(c1)NC(=O)CO2,[Fe],CC(=O)O,,,,test
US20110118245A1,CC(C)(C)c1cc(NC(=O)Nc2cccc(S)c2)no1.CCOc1cc2ncnc(Cl)c2cc1OC>>CCOc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)c2cc1OC,,CC(C)O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04927838,CCOC(=O)C(CC(=O)O)=C(c1cccc(OC)c1)c1cccc(OC)c1>>CCOC(=O)C(CCO)=C(c1cccc(OC)c1)c1cccc(OC)c1,,C1CCOC1,,B,,test
US20100041662A1,OC1CCC(Nc2ccc3ncc(-c4ccc(F)cc4)n3n2)CC1.c1nc[nH]n1>>OC1CCC(Nc2ccc3ncc(-c4ccc(-n5cncn5)cc4)n3n2)CC1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20050267096A1,CCCN1CC(O)(c2cccc3nn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cc23)OC[C@@H]1C>>CCCN(CC(O)c1cccc2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cc12)[C@@H](C)CO,,CCO,O,[BH4-].[Na+],,test
US07071175B1,CC(=O)SCC(C)(Cc1ccc(NC(=O)OC(C)(C)C)nc1)C(=O)OC(C)(C)C>>CC(CS)(Cc1ccc(N)nc1)C(=O)O,,Cl,,,,test
US20140057914A1,O=C(OCc1ccccc1)N1CCN(c2cc(COC3CCCCO3)ccn2)CC1.O=S(Cl)Cl>>O=C(OCc1ccccc1)N1CCN(c2cc(CCl)ccn2)CC1,,ClCCl,,O,O=C([O-])O.[Na+],test
US05418238,CC(C)[N+](=O)[O-].CCOC(O)C(F)(F)F>>CC(C)(C(O)C(F)(F)F)[N+](=O)[O-],,O,,O=C([O-])[O-].[K+].[K+],,test
US20110288117A1,COc1ccc(CN)cc1.O=[N+]([O-])c1cc[n+]([O-])c(Cl)c1>>COc1ccc(CNc2cc([N+](=O)[O-])cc[n+]2[O-])cc1,,CCO,,,,test
US20060041123A1,CC1(C)OC(=O)CC(=O)O1.CCOC(OCC)OCC.Nc1cc2c(cc1Br)OCCO2>>CC1(C)OC(=O)C(=CNc2cc3c(cc2Br)OCCO3)C(=O)O1,,CCO,,,,test
US20140336190A1,CC(C)(C)[Si](OC[C@H]1CCC2(CC2)O1)(c1ccccc1)c1ccccc1>>OC[C@H]1CCC2(CC2)O1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20020165241A1,NC[C@H]1CCN(C(=O)OCc2ccccc2)C[C@H]1O.O=[N+]([O-])c1c(Cl)c(Cl)nc(Cl)c1Cl>>O=C(OCc1ccccc1)N1CCC(CNc2c(Cl)c(Cl)nc(Cl)c2Cl)C(O)C1,,C1CCOC1,,CN1CCOCC1,,test
US20090298823A1,C=C[Sn](C=C)(C=C)C=C.Cc1ccc(S(=O)(=O)n2cc(I)c3c(NC4CC4)nc(Cl)nc32)cc1>>C=Cc1cn(S(=O)(=O)c2ccc(C)cc2)c2nc(Cl)nc(NC3CC3)c12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,CCOC(C)=O,O,test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCC1CCN(C)CC1.Cc1[nH]c2ccc(N)cc2c1C.Cl>>COc1cc2c(Nc3ccc4[nH]c(C)c(C)c4c3)ncnc2cc1OCC1CCN(C)CC1.Cl,,CC(C)O,,,,test
US20070225332A1,COc1ccc(Oc2ncc(C=O)s2)c(Cl)c1.NO>>COc1ccc(Oc2ncc(C=NO)s2)c(Cl)c1,,O,,Cl,c1ccncc1,test
US20080255114A1,COC(=O)c1ccc(F)c(O)c1N.S=C(n1ccnc1)n1ccnc1>>COC(=O)c1ccc(F)c2oc(=S)[nH]c12,,C1CCOC1,,,,test
US20110306607A1,CC(C)(C)OC(=O)N1CCC2(CC1)Oc1ncccc1-n1nccc12.Cl>>Cl.c1cnc2c(c1)-n1nccc1C1(CCNCC1)O2,,CO,ClCCl,C1COCCO1,,test
US04107324,BrBr.CC1(C)CCc2ccc(O)cc21>>CC1(C)CCc2cc(Br)c(O)cc21,,ClC(Cl)(Cl)Cl,,,,test
US20160229816A1,CCOC(=O)CS.O=Cc1cccc(C(F)(F)F)c1F>>CCOC(=O)c1cc2cccc(C(F)(F)F)c2s1,,CS(C)=O,,CCN(CC)CC,,test
US20160264562A1,CCOC(=O)[C@@H](C)OC(=O)C1=C(CN2CCOCC2)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Br.CO>>COC(=O)C1=C(CN2CCOCC2)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Br,,CO,,[Li],,test
US20130217671A1,CC(=O)c1cnc2ccc(Br)cc2c1Nc1ccc(CN2CCN(C)CC2)cc1.CC1(C)OB(c2cc(Cl)c(O)c(Cl)c2)OC1(C)C.Cl>>CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1Nc1ccc(CN2CCN(C)CC2)cc1.Cl,,CO,ClCCl,,,test
US20030018057A1,COC(=O)c1oc(-c2ccccc2)nc1C>>Cc1nc(-c2ccccc2)oc1CO,,C1CCOC1,Cc1ccccc1,CC(C)C[AlH]CC(C)C,,test
US20090247567A1,CC(C)(C)c1cnnn1-c1nc2c(s1)CCOc1cc(Br)ccc1-2>>CC(C)(C)c1cnnn1-c1nc2c(s1)CCOc1ccccc1-2,[Pd],CO,,,,test
US20120122860A1,CCCS(=O)(=O)Nc1ccc(F)c(C(O)c2c[nH]c3ncc(C(F)(F)F)cc23)c1F>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(C(F)(F)F)cc23)c1F,,C1CCOC1,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20160176857A1,Cc1cc(C=O)cc(C)c1O.NC(=O)c1c(Nc2ccc3[nH]ncc3c2)n[nH]c1N>>Cc1cc(CNc2[nH]nc(Nc3ccc4[nH]ncc4c3)c2C(N)=O)cc(C)c1O,C1CCNCC1,CCO,,O,[BH4-].[Na+],test
US20130172302A1,O=C(CCl)c1ccccc1.O=C(O[C@H]1CN2CCC1CC2)C(c1ccccc1)N1CCC(F)(F)CC1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C(c1ccccc1)N1CCC(F)(F)CC1)C2)c1ccccc1.[Cl-],,CCOC(C)=O,,,,test
US20050143421A1,CC(=O)NC[C@H]1CN(c2ccc(N3CCC(O)(CC#N)CC3)c(F)c2)C(=O)O1.CCN(CC)S(F)(F)F>>CC(=O)NC[C@H]1CN(c2ccc(N3CCC(F)(CC#N)CC3)c(F)c2)C(=O)O1,,ClCCl,,,,test
US20100056524A1,O=[N+]([O-])c1ccc(Cl)nc1.OC1CCN(C2CC2)CC1>>O=[N+]([O-])c1ccc(OC2CCN(C3CC3)CC2)nc1,,CN(C)C=O,,[H-].[Na+],,test
US20100286132A1,COC(=O)c1ccc(OCc2c(-c3ccc(F)cn3)noc2C)cn1>>Cc1onc(-c2ccc(F)cn2)c1COc1ccc(C(=O)O)nc1,,C1CCOC1,O,CO,[Li+].[OH-],test
US20080312216A1,Br.CC1(c2ccc(Cl)c(Cl)c2)CCOC1=O.CO>>COC(=O)C(C)(CCBr)c1ccc(Cl)c(Cl)c1,,CC(=O)O,,O=S(Cl)Cl,,test
US20150361100A1,CC(c1cc2ccccn2c1-c1ccccn1)n1nc(I)c2c(N)ncnc21.OB(O)c1cc(O)cc(Cl)c1>>CC(c1cc2ccccn2c1-c1ccccn1)n1nc(-c2cc(O)cc(Cl)c2)c2c(N)ncnc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20020133007A1,Nc1cc(Cl)ccc1N1C(=O)c2ccccc2C1=O.O=C(Cl)c1ccc2ccccc2c1>>O=C(Nc1cc(Cl)ccc1N1C(=O)c2ccccc2C1=O)c1ccc2ccccc2c1,,C1CCOC1,,CCN(CC)CC,O,test
US20120053173A1,CC(=O)c1cc(OCc2ccccc2)ccc1O.CCOC(=O)CBr>>CCOC(=O)c1oc2ccc(OCc3ccccc3)cc2c1C,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04608375,O=c1[nH]c(=O)n(CCCN2CCN(C(c3ccccc3)c3ccccc3)CC2)c2ccccc12.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>O=c1[nH]c(=S)c2ccccc2n1CCCN1CCN(C(c2ccccc2)c2ccccc2)CC1,,c1ccncc1,,,,test
US20160038641A1,O=C(C=Cc1ccc(O)cc1)C1CCCC(=Cc2ccc(O)cc2)C1=O>>O=C(CCc1ccc(O)cc1)C1CCCC(Cc2ccc(O)cc2)C1=O,[Pd],CCOC(C)=O,,,,test
US20120258948A1,Brc1ccc(OC2CCC3(CC2)OCCO3)cc1>>O=C1CCC(Oc2ccc(Br)cc2)CC1,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20090062348A1,CC(=O)OCCBr.O=Cc1cc(OCc2ccccc2)ccc1O>>CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2o1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080262042A1,C1COCCOCCOCCOCCO1.CN(Cc1c[nH]c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C.COC(=O)c1ccc(S(=O)(=O)Cl)o1>>CN(Cc1cn(S(=O)(=O)c2ccc(C3OCCO3)o2)c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20160200725A1,CC(C)(C)OC(=O)N1CC(OCCO)C1.II>>CC(C)(C)OC(=O)N1CC(OCCI)C1,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020064794A1,CC1=Nc2ncccc2C1(C)C.O=C(O)CCCCCBr>>CC1[NH+]=C2C(=CC=CN2CCCCCC(=O)O)C1(C)C.[Br-],,CCOC(C)=O,,,,test
US20120220624A1,CO.O=C(O)C1CC(OCc2ccccc2)C1>>COC(=O)C1CC(OCc2ccccc2)C1,,CO,c1ccccc1,C[Si](C)(C)C=[N+]=[N-],,test
US20160222033A1,COC(=O)C(C)c1c(C)sc2nc(Cn3nc(C(F)(F)F)cc3Cl)cc(=O)n12>>Cc1sc2nc(Cn3nc(C(F)(F)F)cc3Cl)cc(=O)n2c1C(C)CO,,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US03931168,NN1CC(=O)NC1=O.O=C(Cl)C=Cc1ccccc1>>O=C(C=Cc1ccccc1)NN1CC(=O)NC1=O,,c1ccncc1,,Cl,,test
US20020040019A1,CC(=O)N1CCC(C(=O)c2ccc(F)cc2F)CC1.COC(=O)CS>>COC(=O)c1sc2cc(F)ccc2c1C1CCN(C(C)=O)CC1,,C1CCOC1,,[H-].[Na+],,test
US20060122197A1,CC(C)(C)OC(=O)N1CCC[C@@H](NC(=O)C2(c3ccc(Cl)cc3)CCCCC2)C1.Cl>>Cl.O=C(N[C@@H]1CCCNC1)C1(c2ccc(Cl)cc2)CCCCC1,,C1COCCO1,,,,test
US20050113389A1,CN(C)CCOc1ccc(CCCCN)cc1.CSC(=NC(=O)c1nc(Cl)c(N)nc1N)NC(=O)OC(C)(C)C>>CN(C)CCOc1ccc(CCCCN=C(NC(=O)OC(C)(C)C)NC(=O)c2nc(Cl)c(N)nc2N)cc1,,C1CCOC1,CCN(CC)CC,,,test
US04315031,CC1(Cl)CCCCC1.CCO.SCc1ccccc1>>CC1(SCc2ccccc2)CCCCC1=O,,CCO,,[Na+].[OH-],,test
US03989841,CI.O=C(O)C(=O)c1ccc2c(c1)Cc1ccccc1-2>>CC(O)(C(=O)O)c1ccc2c(c1)Cc1ccccc1-2,,CC(=O)O,CCOCC,Cl,[Mg],test
US20070173526A1,CC[C@@H]1C[C@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(C)n2)c2nc(C(F)(F)F)ccc2N1C(=O)OCCOCc1ccccc1>>CC[C@@H]1C[C@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(C)n2)c2nc(C(F)(F)F)ccc2N1C(=O)OCCO,[Pd],CO,,,,test
US04544652,CC(O)[PH](=O)O.CCCCO>>CCCCO[PH](=O)C(C)O,,c1ccccc1,,O,,test
US20130012489A1,COc1ccc(CO)cc1.Clc1ncnc2cc(Br)ccc12>>COc1ccc(COc2ncnc3cc(Br)ccc23)cc1,,Cc1ccccc1,,[H-].[Na+],,test
US20100010220A1,CCN=C(Cl)C1(C)CC1(Cl)Cl.Cl.NNC1C=CC(C(F)(F)F)=CC1(Cl)Cl>>CCNC(=NNc1c(Cl)cc(C(F)(F)F)cc1Cl)C1(C)CC1(Cl)Cl,,Cc1ccccc1,O,CCCCN(CCCC)CCCC,,test
US20070032478A1,O=C(Cl)c1ccc([N+](=O)[O-])cc1.O=C1Cc2ccccc2N1>>O=C1Cc2cc(C(=O)c3ccc([N+](=O)[O-])cc3)ccc2N1,,CN(C)C=O,O,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20050277670A1,CC(C)(C)OC(=O)N1CCC(C(O)c2ccc(OC(F)(F)F)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(C(=O)c2ccc(OC(F)(F)F)cc2)CC1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US05162326,COCCl.N#Cc1ccccc1-c1ccccc1>>N#Cc1ccccc1-c1ccc(CCl)cc1,Cl[Ti](Cl)(Cl)Cl,O,,CCOC(C)=O,Cl,test
US20110294793A1,CC(C)CNCc1cccc(CN(Cc2ccc(-c3ccc(F)cc3)cc2)S(=O)(=O)c2cc(Cl)cc(Cl)c2O)c1.O=C=Nc1cccc(Cl)c1Cl>>CC(C)CN(Cc1cccc(CN(Cc2ccc(-c3ccc(F)cc3)cc2)S(=O)(=O)c2cc(Cl)cc(Cl)c2O)c1)C(=O)Nc1cccc(Cl)c1Cl,,C1CCOC1,,,,test
US20110171159A1,c1ccc(COC[C@H]2O[C@@H](c3ccc(C4CC4)c(Cc4ccc5c(c4)N(Cc4ccccc4)CCO5)c3)[C@H](OCc3ccccc3)[C@@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)cc1>>OC[C@H]1O[C@@H](c2ccc(C3CC3)c(Cc3ccc4c(c3)NCCO4)c2)[C@H](O)[C@@H](O)[C@@H]1O,[Pd],C1CCOC1,,CO,Cl,test
US20120094982A1,Nc1cc(Br)cnc1N.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2cc(Br)cnc2[nH]1,,C1CCOC1,,O,,test
US20070219195A1,CC(C)n1nc(Br)c2ccc(S)cc2c1=O.CSCCCl>>CSCCSc1ccc2c(Br)nn(C(C)C)c(=O)c2c1,,CN(C)C=O,,[H-].[Na+],,test
US20070043048A1,CC(C)(CCc1ccc2ccn([Si](C)(C)C(C)(C)C)c2c1)O[Si](C)(C)C(C)(C)C.CC1(C)CC(Nc2nccc(Cl)n2)CC(C)(C)N1>>CC(C)(O)CCc1ccc2c(-c3ccnc(NC4CC(C)(C)NC(C)(C)C4)n3)c[nH]c2c1,,c1ccncc1,,,,test
US20120010207A1,COc1cc(Cl)ccc1B(O)O.CS(=O)(=O)NC(=O)c1cc(F)c(CBr)cc1F>>COc1cc(Cl)ccc1Cc1cc(F)c(C(=O)NS(C)(=O)=O)cc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20120316200A1,O=C(COc1ccc(-n2ccc(OCc3ccc(F)cc3)cc2=O)cc1)C1CC1>>O=c1cc(OCc2ccc(F)cc2)ccn1-c1ccc(OCC(O)C2CC2)cc1,,CCO,,[BH4-].[Na+],,test
US20160002215A1,CC(C)(C(=O)CC#N)C(F)(F)F.NO>>CC(C)(c1cc(N)on1)C(F)(F)F,,O,,Cl,[Na+].[OH-],test
US04640913,CCCCCCCCCCCCCCOc1ccc(CC(CO)CC2(C)OCCO2)cc1>>CCCCCCCCCCCCCCOc1ccc(CC(CO)CC(C)=O)cc1,,C1COCCO1,,Cl,,test
US20160032047A1,CC(=O)OC(C)=O.O=C(O)Cc1ccc(O)c([N+](=O)[O-])c1>>CC(=O)Oc1ccc(CC(=O)O)cc1[N+](=O)[O-],,O,,Cl,c1ccncc1,test
US20110021556A1,CC(=O)OC(C)=O.Nc1ccc(C2(Cc3ccccc3)CCN(Cc3ccccc3)C2)cc1>>CC(=O)Nc1ccc(C2(Cc3ccccc3)CCN(Cc3ccccc3)C2)cc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20050282888A1,C#CCOc1ccc(CCC(=O)Cl)cc1OC.NCc1ccc(Cl)cc1>>C#CCOc1ccc(CCC(=O)NCc2ccc(Cl)cc2)cc1OC,,O,,C1CCOC1,CCN(CC)CC,test
US20080004309A1,CCOC(=O)c1ncc2c(c1O)c(Br)c(-c1ccc(Cl)cc1)n2-c1ccccc1>>CCOC(=O)c1ncc2c(cc(-c3ccccc3)n2-c2ccccc2)c1O,[Pd],CCO,CN(C)C=O,,,test
US20130178460A1,CC(C)(C)OC(=O)N[C@H]1COCC[C@H]1N.Cc1ccc(NC(=O)c2csc3cnc(Cl)nc23)cc1>>CC1C=CC(NC(=O)c2csc3cnc(N[C@@H]4CCOC[C@@H]4NC(=O)OC(C)(C)C)nc23)=CC1,,C1COCCO1,ClCCl,CCN(C(C)C)C(C)C,,test
US20080132563A1,OC1(c2ccc(Cl)c(C3OCCO3)c2)S[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>O=Cc1cc(C2(O)S[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)ccc1Cl,,O,,C1CCOC1,Cl,test
US20140371203A1,Clc1ncnc2scc(-c3ccccc3)c12.OCC1CCNCC1>>OCC1(c2ncnc3scc(-c4ccccc4)c23)CCNCC1,,CCO,,CCN(CC)CC,,test
US06420409B1,C[C@@H](O)CCO.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCC[C@@H](C)O)cc1,,c1ccncc1,,O,,test
US20140288091A1,C=C[Mg]Br.COC1CCC2(CC1)Cc1ccc(Br)cc1C2=NS(=O)C(C)(C)C>>C=CC1(NS(=O)C(C)(C)C)c2cc(Br)ccc2CC12CCC(OC)CC2,,C1CCOC1,,,,test
US05281571,COc1cc(-c2nn(C)c(C(F)(F)F)c2Cl)c(F)cc1[N+](=O)[O-]>>COc1cc(-c2nn(C)c(C(F)(F)F)c2Cl)c(F)cc1N,[Fe],CC(=O)O,,,,test
US20140323305A1,CN.CO/N=C(C(=O)OC)\C(C)=C/COc1ccn(-c2ccc(Cl)cc2)n1>>CNC(=O)C(=N/OC)/C(C)=C\COc1ccn(-c2ccc(Cl)cc2)n1,,C1CCOC1,O,,,test
US20160130254A1,CCN(c1ccc(C#N)c(Cl)c1)C1CCC=C(c2cncc(OC)c2)C1>>CCN(c1ccc(C#N)c(Cl)c1)C1CCCC(c2cncc(OC)c2)C1,,CCO,,,,test
US20140135338A1,CCOC(=O)c1ccc(C(CCC(F)(F)F)OS(C)(=O)=O)cc1.Nc1cnc2ccccc2c1>>CCOC(=O)c1ccc(C(CCC(F)(F)F)Nc2cnc3ccccc3c2)cc1,,CC#N,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20160257674A1,COC(=O)[C@H]1C[C@@H]1C(=O)c1cc(Cl)c2c(c1)CCO2>>COC(=O)[C@H]1C[C@@H]1C(=O)c1cc(Cl)c2occc2c1,,Cc1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US05292734,C=Cc1ccc2nc(CCCC)n(Cc3ccc(-c4ccccc4-c4nnnn4C(c4ccccc4)(c4ccccc4)c4ccccc4)cc3)c(=O)c2c1.CC1(C)CCC=[N+]1[O-]>>CCCCc1nc2ccc([C@@H]3C[C@H]4CCC(C)(C)N4O3)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,Cc1ccccc1,,,,test
US08742113B2,CCOC(=O)C1=C(Nc2ccc(F)cc2)OC(=Cc2c[nH]c3ncccc23)C1=O.OC1CCCC(O)C1>>O=C(OC1CCCC(O)C1)C1=C(Nc2ccc(F)cc2)OC(=Cc2c[nH]c3ncccc23)C1=O,[Zn],CC(=O)N(C)C,,,,test
US20150322008A1,CI.O=C(O)c1c(Cl)cc([N+](=O)[O-])cc1Cl>>COC(=O)c1c(Cl)cc([N+](=O)[O-])cc1Cl,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080146637A1,CSC(SC)SC.O=Cc1ccccc1-c1ccc2[nH]c(COc3ccc(C(F)(F)F)cc3)nc2c1>>CSC(SC)(SC)C(O)c1ccccc1-c1ccc2[nH]c(COc3ccc(C(F)(F)F)cc3)nc2c1,,C1CCOC1,,[Li]CCCC,,test
US06841549B1,COc1ccc(N)cn1.Cl.Nc1c(Cl)ncnc1Cl>>COc1ccc(Nc2ncnc(Cl)c2N)cn1.Cl,,O,,CCO,,test
US20090137561A1,CCC(C)(C)C(O)c1cc(C(=O)OC)ccc1-c1cc(OC)ccc1F.CI>>CCC(C)(C)C(OC)c1cc(C(=O)OC)ccc1-c1cc(OC)ccc1F,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20160166560A1,COc1cccc(CN2CCC(N(C)C(=O)n3cnc(-c4ccc(OS(N)(=O)=O)cc4)c3)CC2)c1.Cl>>COc1cccc(CN2CCC(N(C)C(=O)n3cnc(-c4ccc(OS(N)(=O)=O)cc4)c3)CC2)c1.Cl,,CCOC(C)=O,CO,,,test
US20140235441A1,CC1(c2ccc(Oc3ccc(Cl)cc3)cc2Cl)CO1.c1nc[nH]n1>>CC(O)(Cn1cncn1)c1ccc(Oc2ccc(Cl)cc2)cc1Cl,,CN1CCCC1=O,,[Na+].[OH-],,test
US04076812,FC1=Cc2ccccc2Nc2ccccc21.O=C(Cl)Cl>>O=C(Cl)N1c2ccccc2C=C(F)c2ccccc21,,Cc1ccccc1,,,,test
US20060135578A1,CCn1cc(CCl)cn1.Cl.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CCn1cc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cn1.Cl.[Cl-],,CC#N,,,,test
US20120083469A1,CCOC(=O)C(CCCCB1OC(C)(C)C(C)(C)O1)(COC(C)=O)NC(=O)OC(C)(C)C>>CCOC(=O)C(CO)(CCCCB1OC(C)(C)C(C)(C)O1)NC(=O)OC(C)(C)C,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US06248753B1,CCCCNCC.Cc1cc(C)c(-n2nc(C)c3c(Cl)cc(C)nc32)c(C)c1>>CCCCNCCc1cc(C)nc2c1c(C)nn2-c1c(C)cc(C)cc1C,,CS(C)=O,,,,test
US04297350,CC=O.CO[C@H]1CC[C@H]2[C@@H]3CC[C@H]4CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C>>CC=C1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](OC)[C@@]4(C)CC[C@@H]32)CC1=O,,CCO,,CC(=O)O,[K+].[OH-],test
US04200641,BrC(c1ccccc1)c1ccccc1.CCOC(=O)N1CCC(O)CC1>>CCOC(=O)N1CCC(OC(c2ccccc2)c2ccccc2)CC1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20010027196A1,CS(=O)c1nc(N)nc(-c2ccco2)c1Cl.OCc1ccccn1>>Nc1nc(OCc2ccccn2)c(Cl)c(-c2ccco2)n1,,COCCOC,,C1CCC2=NCCCN2CC1,,test
US05200416,COC(=O)C1Cc2c([nH]c3ccccc23)C(c2ccccc2)N1C(=O)C(C)CSC(C)=O>>COC(=O)C1Cc2c([nH]c3ccccc23)C(c2ccccc2)N1C(=O)C(C)CS,,CO,,,,test
US20030208018A1,C=C(C)C(=O)OC.C=C(C)C(=O)OCC1CO1.C=C(C)C(=O)OCCS(=O)(=O)c1ccc(C)cc1.C=CC(=O)OCCCO>>C=C(C)C(=O)OC.C=C(C)C(=O)OCC1CO1.C=C(C)C(=O)OCCS(=O)(=O)c1ccc(C)cc1.C=CC(=O)OCCCO,,C1CCOC1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20090318408A1,C=O.NCCc1ccccc1.c1ccc2[nH]nnc2c1>>c1ccc(CCNCn2nnc3ccccc32)cc1,,CCOCC,,,,test
US20160031901A1,COC(=O)NC1=C(C#N)C(=O)CS1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)Nc1scc(OS(=O)(=O)C(F)(F)F)c1C#N,CCN(CC)CC,ClCCl,,,,test
US20140073620A1,Cn1ccc(N)n1.NC(=O)C1(c2ccccc2CCc2nc(Cl)ncc2Cl)CC1>>Cn1ccc(Nc2ncc(Cl)c(CCc3ccccc3C3(C(N)=O)CC3)n2)n1,,C1COCCO1,CCOCC,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20150005304A1,Cc1cc(C(=O)N2CCC(=CC(=O)CC(O)c3cncc(F)c3)CC2)ccc1OC(C)C>>Cc1cc(C(=O)N2CCC(=CC(=O)CC(=O)c3cncc(F)c3)CC2)ccc1OC(C)C,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20070124152A1,COC(=O)Cl.NCCn1c(=O)c(C(=O)NCCN2CCOCC2)c(O)c2ncc(Cc3ccc(F)cc3)cc21>>COC(=O)NCCn1c(=O)c(C(=O)NCCN2CCOCC2)c(O)c2ncc(Cc3ccc(F)cc3)cc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20130131016A1,CCOCOC(C)(C)c1c(B2OC(C)(C)C(C)(C)O2)ccc(C)c1F>>Cc1ccc2c(c1F)C(C)(C)OB2O,,C1CCOC1,,Cl,,test
US20100311966A1,CCCCOC(=O)c1nc(N2CC[C@H](NC(=O)OCc3ccccc3)[C@H](OC)C2)oc1CC>>CCCCOC(=O)c1nc(N2CC[C@H](N)[C@H](OC)C2)oc1CC,[Pd],CO,,CCOC(C)=O,,test
US20080194696A1,O=C1OCC2C[C@]12c1cccc2ccccc12>>OCC1C[C@@]1(CO)c1cccc2ccccc12,,C1CCOC1,,ClCCl,,test
US20120022056A1,C=CCc1cccc([N+](=O)[O-])c1OCC#CC>>C=CCc1cccc(N)c1OCC#CC,[Fe],CC(=O)O,,,,test
US20140235584A1,CI.Cn1nnnc1Nc1ccc(Br)cn1>>CN(c1ccc(Br)cn1)c1nnnn1C,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20090318651A1,CCCCCCc1csc(Cl)n1.O=C1CCC(=O)N1I>>CCCCCCc1nc(Cl)sc1I,,CC#N,,,,test
US20160137637A1,N#Cc1ccnc(N)c1.O=C(O)c1csc(-c2ccc3c(c2)CCO3)n1>>N#Cc1ccnc(NC(=O)c2csc(-c3ccc4c(c3)CCO4)n2)c1,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120309745A1,O=C(NC12CCC(CC1)Cn1c2nc(-c2nnc(Cc3ccc(F)cc3)o2)c(OCc2ccccc2)c1=O)OCc1ccccc1>>NC12CCC(CC1)Cn1c2nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c1=O,,ClCCl,,Br,CC(=O)O,test
US04883747,COc1cc(C=C(C#N)C#N)cc(OC)c1OC.[C-]#N>>COc1cc(C(C#N)C(C#N)C#N)cc(OC)c1OC,,CC(=O)O,O,CCO,,test
US20130274287A1,CI.N#Cc1ccc(-c2cncc3c2CCCC3O)cc1>>COC1CCCc2c(-c3ccc(C#N)cc3)cncc21,,CN(C)C=O,,[H-].[Na+],,test
US20040106606A1,CCOC(=O)C(=O)Cc1ccc(C(C)(C)C)cc1[N+](=O)[O-]>>CCOC(=O)c1cc2ccc(C(C)(C)C)cc2[nH]1,[Fe],CC(=O)O,,CCO,,test
US20030166686A1,CS(=O)(=O)OCCNC(=O)OCc1ccccc1.Oc1ccc(-c2cocn2)cc1>>O=C(NCCOc1ccc(-c2cocn2)cc1)OCc1ccccc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130281433A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.Fc1cnc(Cl)nc1Cl>>C=C(OCC)c1nc(Cl)ncc1F,,CN(C)C=O,,,,test
US20090054407A1,CC(C)(C)OC(=O)n1c(-c2ccc(O)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21.Cc1nn(C)c(C)c1S(=O)(=O)Cl>>Cc1nn(C)c(C)c1S(=O)(=O)Oc1ccc(-c2cc3cc(CN4CCCCC4)ccc3n2C(=O)OC(C)(C)C)c2c1CNC2=O,,CC#N,,CCN(CC)CC,,test
US20090162319A1,Cc1cc(Br)cc(C)c1S.Cc1nc(Cl)nc(Cl)c1[N+](=O)[O-]>>Cc1cc(Br)cc(C)c1Sc1nc(Cl)nc(C)c1[N+](=O)[O-],,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20140343282A1,O=C1NC(=O)c2ccccc21.O=[N+]([O-])c1ccc(CBr)c(C(F)(F)F)c1>>O=C1c2ccccc2C(=O)N1Cc1ccc([N+](=O)[O-])cc1C(F)(F)F,,CN(C)C=O,,[K],,test
US20100029615A1,CCOC(C)=O.CI.O=C1COc2ccc(C(=O)O)cc2N1>>COC(=O)c1ccc2c(c1)N(C)C(=O)CO2,O=[Ag-],CCOC(C)=O,,CN(C)C=O,,test
US20130274255A1,C[Si](C)(C)CCOCn1nc(-c2ccc(N3CCCC3)cc2)c2c1-c1ccsc1C2>>c1cc2c(s1)Cc1c(-c3ccc(N4CCCC4)cc3)n[nH]c1-2,,CO,,Cl,,test
US04960787,CNC(=O)N(OCc1ccccc1)C(C)c1ccn(-c2c(C)cccc2C)c1>>CNC(=O)N(O)C(C)c1ccn(-c2c(C)cccc2C)c1,,CCOC(C)=O,,,,test
US20100113462A1,CC(C)O.NC1(C(=O)O)Cc2ccccc2C1.O=C(Cl)c1cccc2c1OC(F)(F)O2>>CCOC(=O)C1(NC(=O)c2cccc3c2OC(F)(F)O3)Cc2ccccc2C1,CN(C)c1ccncc1,CC(C)O,ClCCl,CCN(C(C)C)C(C)C,,test
US20060217562A1,BrCc1ccccc1.NC(=O)c1n[nH]c2c1CCC2>>NC(=O)c1c2c(nn1Cc1ccccc1)CCC2,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20040214832A1,CC(C)(C)OC(=O)N1CC(=O)N(c2ccc(OCCCO)cc2)[C@@H](COc2ccc3ccccc3c2)C1.Fc1ccccc1CBr>>CC(C)(C)OC(=O)N1CC(=O)N(c2ccc(OCCCOCc3ccccc3F)cc2)[C@@H](COc2ccc3ccccc3c2)C1,,CN(C)C=O,,[H-].[Na+],,test
US20150011548A1,CC(=O)Nc1cc(N)cc(-c2ncccc2F)c1.O=[N+]([O-])c1cc(Br)ccc1F>>CC(=O)Nc1cc(Nc2ccc(Br)cc2[N+](=O)[O-])cc(-c2ncccc2F)c1,,CN(C)C=O,,[F-].[K+],,test
US20130150339A1,COc1cc(Cl)ccc1B(O)O.COc1ccc(CN(c2ccncn2)S(=O)(=O)c2ccc3c(Cl)nccc3c2)cc1>>COc1ccc(CN(c2ccncn2)S(=O)(=O)c2ccc3c(-c4ccc(Cl)cc4OC)nccc3c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20070219216A1,CC(C)Oc1ccc(F)cc1N1CCN(CCCN)CC1.CC1=C(C)C(=O)OC1=O>>CC1=C(C)C(=O)N(CCCN2CCN(c3cc(F)ccc3OC(C)C)CC2)C1=O,,Cc1ccccc1,,,,test
US20110172252A1,CC(C)(O)c1cccc(CO[Si](C)(C)C(C)(C)C)n1.CI>>COC(C)(C)c1cccc(CO[Si](C)(C)C(C)(C)C)n1,,CN(C)C=O,,[H-].[Na+],,test
US04102896,CC1(C)CC(=O)CC(=O)C1.ClP(Cl)(Cl)(Cl)Cl>>CC1(C)CC(=O)C=C(Cl)C1,,ClC(Cl)Cl,,,,test
US20150119380A1,CC(=O)CCl.CCOC(=O)CC(N)=S>>CCOC(=O)Cc1nc(C)cs1,,CN(C)C=O,,,,test
US20120178760A1,CCOC(=O)c1cn(Cc2ccc(-c3ccccc3)cc2)c2c(c1=S)CCC2.NNc1ccccc1F>>O=c1c2cn(Cc3ccc(-c4ccccc4)cc3)c3c(c-2nn1-c1ccccc1F)CCC3,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20130116236A1,CC(C)(C)c1nc(N2CCC(F)(F)C2)c2nn[nH]c2n1.C[C@H](O)c1ccccc1Cl>>C[C@H](c1ccccc1Cl)N1Nc2nc(C(C)(C)C)nc(N3CCC(F)(F)C3)c2N1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030130354A1,CCOP(=O)(OCC)C(C#N)c1ccccc1.O=CC12CC3CC(CC(C3)C1)C2>>N#CC(=CC12CC3CC(CC(C3)C1)C2)c1ccccc1,,C1CCOC1,,O,[H-].[Na+],test
US08318722B2,CC(C)N(Cc1ccccc1)c1cnc(CN(CCO)Cc2ccccc2)c(Cl)n1>>CC(C)N(Cc1ccccc1)c1cnc2c(n1)OCCN(Cc1ccccc1)C2,,CN(C)C=O,,O,CC(C)(C)[O-].[K+],test
US20110034507A1,CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CCl.COC(=O)c1cc(-c2ccc3cc(O)ccc3c2)ccn1>>COC(=O)c1cc(-c2ccc3cc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)ccc3c2)ccn1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20040138462A1,CCOC(=O)COc1ccc(S(=O)(=O)c2ccc(CCNC[C@H](O)c3cccc(Cl)c3)cc2)cc1Cl.Cl>>CCOC(=O)COc1ccc(S(=O)(=O)c2ccc(CCNC[C@H](O)c3cccc(Cl)c3)cc2)cc1Cl.Cl,,CCO,Cl,,,test
US20120178716A1,CCCP(=O)(CCC)c1ccc(N)cc1.Clc1nc(I)nc2c1ncn2C1CCCCO1>>CCCP(=O)(CCC)c1ccc(Nc2nc(I)nc3c2ncn3C2CCCCO2)cc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20090306041A1,CN1CCN(c2ccc(N)nc2)CC1.Cn1cc(Br)cc(Br)c1=O>>CN1CCN(c2ccc(Nc3cc(Br)cn(C)c3=O)nc2)CC1,,C1COCCO1,,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US05304644,O=Cc1ccccc1Oc1ccc(C(F)(F)F)cc1[N+](=O)[O-]>>FC(F)(F)c1ccc2c(c1)NCc1ccccc1O2,[Ni],CCO,,[H][H],,test
US20160152605A1,CC(C)(C)OC(=O)N1CCC(=CC#N)CC1c1ccccc1>>CC(C)(C)OC(=O)N1CCC(CC#N)CC1c1ccccc1,[Pd],CO,,N#N,,test
US20040259927A1,CC(=O)C(N)c1ccccc1.Cl.N#CNc1c(Cl)cccc1Cl>>Cc1nc(Nc2c(Cl)cccc2Cl)[nH]c1-c1ccccc1.Cl,,CCO,,CCN(CC)CC,,test
US04223137,CCC(NC(C)C)C(O)c1ccc(O)c2c1CCC(=O)N2.C[O-].O=c1ccc2ccccc2[nH]1>>CCC(NC(C)C)C(O)c1ccc(OC(=O)C2CCCCC2)c2c1CCC(=O)N2,,CO,,Cl,,test
US20030162985A1,CCO[Si](OCC)(OCC)OCC.FC(F)=C(F)Cl>>CCO[Si](OCC)(OCC)C(F)=C(F)F,,CCOCC,,[Li]C(C)CC,,test
US20130059834A1,CCCC[Sn](CCCC)(CCCC)c1cnc2ccccn12.C[C@@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Br)nc12)C(=O)N1CC(C#N)C1>>C[C@@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3cnc4ccccn34)nc12)C(=O)N1CC(C#N)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US20030078249A1,CC(C)(C)OC(=O)N1CCC[C@H]1CO.COC(=O)c1ccc(O)nc1>>COC(=O)c1ccc(OCC2CCCN2C(=O)OC(C)(C)C)nc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070161645A1,COc1ccc(C=Cc2cnc(Nc3cccc(N4CCN(C(=O)OC(C)(C)C)CC4)c3)s2)cc1>>Oc1ccc(C=Cc2cnc(Nc3cccc(N4CCNCC4)c3)s2)cc1,,ClCCl,,BrB(Br)Br,,test
US20160039838A1,C1CO[C@H]2CNC[C@H]2O1.CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)/C=C/CBr>>CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)/C=C/CN1C[C@H]2OCCO[C@H]2C1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,O,test
US20110294776A1,CC(C)(C)[Si](C)(C)OCCBr.Nc1ncnn2c(Cc3ccc4c(c3)CNCC4)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12>>Nc1ncnn2c(Cc3ccc4c(c3)CN(CCO)CC4)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12,,CN(C)C=O,,CCN(CC)CC,[I-].[Na+],test
US04795817,COC(=O)c1cc(-c2cc(C)[nH]c2C)nn1C.NO>>COC(=O)c1cc(N)nn1C,,CCO,O,Cl,[K+].[OH-],test
US20140323418A1,CC(C)(C)OC(=O)N[C@H]1CCCC(F)(F)[C@H]1N=[N+]=[N-]>>CC(C)(C)OC(=O)N[C@H]1CCCC(F)(F)[C@H]1N,[Pd],CCOC(C)=O,,[H][H],,test
US07329763B1,CN(CC(=O)O)C(=N)N.O=C1CCC(C(=O)O)N1>>CN(CC(=O)O)C(=N)N.O=C1CC[C@@H](C(=O)O)N1,,CCOC(C)=O,,CCO,,test
US20050070547A1,COc1cc(Cl)c2ccc(-c3ncccc3C(F)(F)F)nc2n1.Nc1ccc(C(F)(F)F)cc1>>Oc1cc(Nc2ccc(C(F)(F)F)cc2)c2ccc(-c3ncccc3C(F)(F)F)nc2n1,,CC(C)O,,CCOCC,Cl,test
US04826836,CC(C)(Oc1cccc(C(F)(F)F)c1)C1(C)OCC(CN2CCCCC2)O1.O=C1NS(=O)(=O)c2ccccc21>>CC(C)(Oc1cccc(C(F)(F)F)c1)C1(C)OCC(CN2CCCCC2)O1.O=C1NS(=O)(=O)c2ccccc21,,CCO,,,,test
US04988723,CC1(C)Oc2ccc(C#N)cc2[C@@H]2O[C@@H]21.N#CN=C1NCCS1>>CC1(C)Oc2ccc(C#N)cc2[C@@H](N2CCSC2=NC#N)[C@@H]1O,,CCN(CC)CC,,,,test
US20100190747A1,CCN(C(C)C)C(C)C.COC(=O)C(C)CCl.O=c1c2[nH]ccc2[nH]c(=S)n1-c1ccc(OCC(F)(F)F)cc1>>COC(=O)C(C)CCSc1nc2cc[nH]c2c(=O)n1-c1ccc(OCC(F)(F)F)cc1,,CN(C)C=O,,,,test
US20050250836A1,CC(C)(C)[Si](C)(C)OCCCn1ccc2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O>>O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2ccn1CCCO,,C1COCCO1,,O=S(=O)(O)O,,test
US20090221555A1,C1CCNC1.CC1(C)CCCN(C(=O)Oc2ccc([N+](=O)[O-])cc2)c2cc([N+](=O)[O-])ccc21>>CC1(C)CCCN(C(=O)N2CCCC2)c2cc([N+](=O)[O-])ccc21,,C1CCOC1,,,,test
US20120046268A1,COCCN=C=O.O=C(NC1CNCC(c2ccc(OC(F)(F)F)cc2)C1)c1ccccc1>>COCCNC(=O)N1CC(NC(=O)c2ccccc2)CC(c2ccc(OC(F)(F)F)cc2)C1,,C1CCOC1,,CCN(CC)CC,,test
US20100305145A1,CCOC(=O)C(=O)Cl.CCOC(=O)C(C)C[C@H](N)Cc1ccc(-c2cccc(Cl)c2)cc1>>CCOC(=O)C(=O)N[C@H](Cc1ccc(-c2cccc(Cl)c2)cc1)CC(C)C(=O)OCC,,CN(C)C=O,,Cl,,test
US20150239827A1,CCOC(=O)CC[C@@H]1Cc2ccccc2C2(C1)OCCO2>>O=C(O)CC[C@H]1CC(=O)c2ccccc2C1,,C1CCOC1,O,[Li+].[OH-],,test
US04509972,COc1nc(N)nc2nccnc12.O=C=NS(=O)(=O)c1ccccc1C(F)(F)F>>NC(=O)NS(=O)(=O)c1ccccc1C(F)(F)F,,ClCCl,,,,test
US20160228586A1,CC(C)(C)OC(=O)n1c2ccncc2c2ccc(-c3ccc[n+]([O-])c3)cc21.CN(C)C.Cc1ccc(S(=O)(=O)OS(=O)(=O)c2ccc(C)cc2)cc1>>CC(C)(C)OC(=O)n1c2ccncc2c2ccc(-c3ccc([N+](C)(C)C)nc3)cc21.Cc1ccc(S(=O)(=O)[O-])cc1,,ClCCl,,C1CCOC1,,test
US20110201604A1,CC(C)(C)OC(=O)N(CCN)CCF.Cn1c(Nc2nc3ccc(Cl)cc3s2)nc2cc(C(=O)O)ccc21>>Cn1c(Nc2nc3ccc(Cl)cc3s2)nc2cc(C(=O)NCCN(CCF)C(=O)OC(C)(C)C)ccc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090005558A1,CC(C)(C)OC(=O)N1CC2CNCC(C1)O2.N#Cc1ccc(S(=O)(=O)NCCCBr)cc1>>CC(C)(C)OC(=O)N1CC2CN(CCCNS(=O)(=O)c3ccc(C#N)cc3)CC(C1)O2,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040266822A1,CC(C)=C(C)C.NC(N)=O>>CC(C)C(C)(C)NC(N)=O,,CC(=O)O,O,O=S(=O)(O)O,[Na+].[OH-],test
US20090170907A1,CC(=O)Cl.N#Cc1ccc(C(Cc2nnc(-c3ccc(N)cc3)o2)NC(F)(F)F)cc1C(F)(F)F>>CC(=O)Nc1ccc(-c2nnc(CC(NC(F)(F)F)c3ccc(C#N)c(C(F)(F)F)c3)o2)cc1,,C1CCOC1,,,,test
US04028089,CCCCCC.CCCCO.CCCCOC(=O)C(C#N)=C(SC)SC.CSC(SC)=C(C#N)C#N>>CCCCOC(=O)C(C#N)=C1Nc2ccccc2O1,,CCCCO,,CCOC(C)=O,,test
US05972965,CCOC(=O)COc1cccc(CBr)c1.c1ccc(-c2nc([C@H]3CCCN3)oc2-c2ccccc2)cc1>>CCOC(=O)COc1cccc(CN2CCC[C@@H]2c2nc(-c3ccccc3)c(-c3ccccc3)o2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040127574A1,CCOC(=O)CC(=O)c1ccc(F)c(F)c1.FC(F)(F)c1ccc(CBr)cc1>>CCOC(=O)C(Cc1ccc(C(F)(F)F)cc1)C(=O)c1ccc(F)c(F)c1,,COCCOC,,O,[H-].[Na+],test
US20160218303A1,N#Cc1cccc(F)c1[N+](=O)[O-].Nc1ccc2c(c1)oc1ccccc12>>N#Cc1cccc(Nc2ccc3c(c2)oc2ccccc23)c1[N+](=O)[O-],,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US04652405,CCOC(C)OC(C)(C)[C@H](F)CC[C@@H](COS(=O)(=O)c1ccc(C)cc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC5CCCCO5)C[C@H](OC5CCCCO5)[C@]4(C)[C@H]3CC[C@]12C>>CCOC(C)OC(C)(C)[C@H](F)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC5CCCCO5)C[C@H](OC5CCCCO5)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110311461A1,O=C(CBr)c1ccsc1.O=C(O[C@H]1CN2CCC1CC2)C(Nc1ccccc1)c1csc2ccccc12>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C(Nc1ccccc1)c1csc3ccccc13)C2)c1ccsc1.[Br-],,CCOC(C)=O,,,,test
US06136817,CCCO[C@@]12CCC(=O)[C@]3(C)Oc4c(OC)ccc5c4[C@]13CCN[C@@H]2C5.Cl.ClCC1CC1>>CCCO[C@@]12CCC(=O)[C@]3(C)Oc4c(OC)ccc5c4[C@]13CCN(CC1CC1)[C@@H]2C5.Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110039852A1,CC(=O)O.N#CCc1cc(Br)ccc1F.O=S(=O)(O)O>>O=C(O)Cc1cc(Br)ccc1F,,O,,,,test
US20150274691A1,CC(=O)CCSc1ccccc1.C[Si](C)(C)Cl>>C=C(CCSc1ccccc1)O[Si](C)(C)C,,C1CCOC1,CCCCC,CC(C)[N-]C(C)C.[Li+],,test
US20090131400A1,CC(C)(C)OC(=O)CCN.FC(F)(F)c1cc(-c2sc3ccc(CBr)cc3c2Cl)ccc1-c1ccccc1>>CC(C)(C)OC(=O)CCNCc1ccc2sc(-c3ccc(-c4ccccc4)c(C(F)(F)F)c3)c(Cl)c2c1,,CCOC(C)=O,CN(C)C=O,Cl,O=C([O-])[O-].[K+].[K+],test
US20060035908A1,COC(=O)c1cc(C)ccc1NC(=O)c1ccc(Cl)cc1.O=C1CCC(=O)N1Br>>COC(=O)c1cc(CBr)ccc1NC(=O)c1ccc(Cl)cc1,,CCOC(C)=O,c1ccccc1,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20110053953A1,Cc1nc(-c2cccc(N)c2)cc2c1C(=O)N(Cc1ccc(OC(F)(F)F)cc1)C2.O=CO>>Cc1nc(-c2cccc(NC=O)c2)cc2c1C(=O)N(Cc1ccc(OC(F)(F)F)cc1)C2,,O=CO,,CC(=O)OC(C)=O,,test
US20040053908A1,COCCOc1cc2nccc(Cl)c2cc1C#N.O=[N+]([O-])c1ccc(O)cc1>>COCCOc1cc2nccc(Oc3ccc([N+](=O)[O-])cc3)c2cc1C#N,,CCOC(C)=O,,Cc1cccc(C)n1,,test
US20160096827A1,C[C@H]1CN(c2ccc(Nc3ncnc(-c4ccc(O[C@H]5CCNC[C@H]5F)c(C#N)c4)n3)cc2)CCN1C1COC1.O=C1CC[C@@H](C(=O)O)N1>>C[C@H]1CN(c2ccc(Nc3ncnc(-c4ccc(O[C@H]5CCN(C(=O)[C@@H]6CCC(=O)N6)C[C@H]5F)c(C#N)c4)n3)cc2)CCN1C1COC1,,ClCCl,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06140320,CC(Br)C(=O)Br.OC(C#CC1CC1)(c1cc(Cl)ccc1NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(F)(F)F>>C[C@@H]1O[C@](/C=C/C2CC2)(C(F)(F)F)c2cc(Cl)ccc2NC1=O,,CCOCC,,c1ccncc1,,test
US03962224,CCOP(=O)(OCC)C(NC=S)C(=O)OCC(Cl)(Cl)Cl.COCOCC(=O)CCl>>COCOCC1=C(C(=O)OCC(Cl)(Cl)Cl)N=CSC1,,CC(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US04843087,Cc1cc(CCCCCOc2ccc(C=O)cc2)on1.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>Cc1cc(CCCCCOc2ccc(-c3cnco3)cc2)on1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20070015742A1,O=C(Cl)c1ccccc1.O=C(c1ccccc1)c1ccc(Cc2cccs2)[nH]1>>O=C(c1ccccc1)c1ccc(Cc2ccc(C(=O)c3ccccc3)s2)[nH]1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20130261298A1,COc1ccc(CCN)cc1OC.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccc(CCNC(=O)C(F)(F)F)cc1OC,,CCOC(C)=O,,O,,test
US20140110642A1,CC(C)(C)c1nc2ccccc2c2nccn12.O=C1CCC(=O)N1Br>>CC(C)(C)c1nc2ccccc2c2ncc(Br)n12,,C1CCOC1,,,,test
US08497264B2,COc1ccc2c(c1)C1(COCC(=O)N1)c1cc(Br)ccc1O2>>O=C1COC[C@@]2(N1)c1cc(O)ccc1Oc1ccc(Br)cc12,,ClCCl,O,BrB(Br)Br,,test
US20130035318A1,C=C(C)[C@@H]1CC[C@]2(NCCNC3CCS(=O)(=O)C3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NCCNC3CCS(=O)(=O)C3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1COCCO1,,[Na+].[OH-],,test
US20070185165A1,CCOC(=O)CCc1nonc1C(=O)Nc1ccc(F)c(Cl)c1.NO>>CCOC(=O)CCc1nonc1C(=NO)Nc1ccc(F)c(Cl)c1,,CO,c1ccccc1,ClP(Cl)(Cl)(Cl)Cl,,test
US20070219228A1,NCC1(O)CCCC1.O=[N+]([O-])c1cnc2cc(Br)cnc2c1Cl>>O=[N+]([O-])c1cnc2cc(Br)cnc2c1NCC1(O)CCCC1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20120083475A1,CCOC(=O)/C(N)=N/OC(=O)Cc1cc(F)ccc1F>>CCOC(=O)c1noc(Cc2cc(F)ccc2F)n1,,c1ccncc1,,,,test
US20120142659A1,CN[C@H](CN1CCCC(F)(F)C1)C(C)C.O=C(O)c1ccc(F)c(Cl)c1>>CC(C)[C@@H](CN1CCCC(F)(F)C1)N(C)C(=O)c1ccc(F)c(Cl)c1,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US05270465,CN(C)C=O.Cc1ccc(OCc2nc(N)c3nccnc3n2)cc1>>Cc1ccc(OCc2nc3nccnc3c(=O)[nH]2)cc1,,[Na+],[OH-],CCO,,test
US04785019,O=C(Cl)C(=O)Cl.O=C(O)c1cccc2ccccc12>>O=C(Cl)c1cccc2ccccc12,CN(C)C=O,ClCCl,,,,test
US04927926,CCOC(=O)c1cn(C2CC2)c2c(F)c(N3CC(NC(=O)C(F)(F)F)C3)c(F)cc2c1=O>>NC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,,CCO,,[Na+].[OH-],,test
US20080261967A1,CCC=C[Mg]Br.COc1ccc(F)cc1CCC=O>>CC=CCC(O)CCc1cc(F)ccc1OC,,C1CCOC1,,[Cl-].[NH4+],,test
US20110311474A1,CCOC(=O)[C@H]1C[C@@H](OCc2ccc(C#N)cc2)C1>>N#Cc1ccc(CO[C@@H]2C[C@H](C(=O)O)C2)cc1,,C1COCCO1,,[Na+].[OH-],,test
US20110060009A1,COC(=O)/C=C/c1ccc(CN2CCC[C@@H]2Cc2c[nH]c3ccccc23)cc1.COC(=O)C(F)C(=O)OC>>COC(=O)/C(F)=C/c1ccc(CN2CCC[C@@H]2Cc2c[nH]c3ccccc23)cc1,,C1CCOC1,,[H-].[Na+],,test
US20160016948A1,CC(=O)Cl.Cc1nc2cnc(Nc3ccnc(-c4cnn(S(=O)(=O)C5CCNC5)c4)n3)cc2n1C(C)C>>CC(=O)N1CCC(S(=O)(=O)n2cc(-c3nccc(Nc4cc5c(cn4)nc(C)n5C(C)C)n3)cn2)C1,,C1CCOC1,,CCN(CC)CC,,test
US05955607,CC1(C)Oc2ccc(Cl)cc2C(CS(=O)(=O)NCC(=O)O)C1O.NCCc1ccccc1>>CC1(C)Oc2ccc(Cl)cc2C(CS(=O)(=O)NCC(=O)NCCc2ccccc2)C1O,,C1CCOC1,CCOC(C)=O,O=C(n1ccnc1)n1ccnc1,,test
US20130165440A1,Cc1nn(C(=O)OC(C)(C)C)c2cc(-c3nnc(Nc4cc(CCCN(C)C)cc(C(F)(F)F)c4)c4ccccc34)ccc12.O=C(O)C(F)(F)F>>Cc1n[nH]c2cc(-c3nnc(Nc4cc(CCCN(C)C)cc(C(F)(F)F)c4)c4ccccc34)ccc12.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20160145247A1,CNC(CO)c1cccc(Br)c1.COC(=O)Cc1ccccc1OCc1cccc(B2OC(C)(C)C(C)(C)O2)c1>>CNC(CO)c1cccc(-c2cccc(COc3ccccc3CC(=O)O)c2)c1,,CN(C)C=O,,,,test
US20130012532A1,BrBr.CC(C)(CC=O)CN1C(=O)c2ccccc2C1=O.COC(=O)CP(=O)(OCC(F)(F)F)OCC(F)(F)F>>COC(=O)/C(Br)=C\CC(C)(C)CN1C(=O)c2ccccc2C1=O,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US04515799,CCOC(=O)C1=C(COCC(N)=O)NC(C)=C(C(=O)OC)C1c1ccccc1Cl>>CCOC(=O)C1=C(COCC#N)NC(C)=C(C(=O)OC)C1c1ccccc1Cl,,C1COCCO1,O,O=C(OC(=O)C(F)(F)F)C(F)(F)F,c1ccncc1,test
US04088779,CCOC(C=O)OCC.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(/C=C/C(=O)OC)OCC,,c1ccccc1,,,,test
US20100184778A1,CC1CCN(Cc2ccc(N)cc2)CC1.O=C(O)c1cncc(Br)c1>>CC1CCN(Cc2ccc(NC(=O)c3cncc(Br)c3)cc2)CC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20090042931A1,Brc1ncc[nH]1.CC(C)Cc1cc(-c2cccc(CBr)c2)c(S(=O)(=O)NC(C)(C)C)s1>>CC(C)Cc1cc(-c2cccc(Cn3ccnc3Br)c2)c(S(=O)(=O)NC(C)(C)C)s1,,CS(C)=O,ClCCl,[Na+].[OH-],,test
US20150073011A1,C=CCON(C(=O)OC(C)(C)C)[C@H]1CN(C(=O)OC(C)(C)C)[C@H](CO[Si](C)(C)C(C)(C)C)C=C1COC>>C=CCON(C(=O)OC(C)(C)C)[C@H]1CN(C(=O)OC(C)(C)C)[C@H](CO)C=C1COC,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20160075701A1,CC(C)(C)C(=O)Nc1cncc(-c2ccc3c(c2)c(C=O)nn3COCC[Si](C)(C)C)c1.Nc1ccnc(-c2ccc(F)cc2)c1N>>CC(C)(C)C(=O)Nc1cncc(-c2ccc3c(c2)c(-c2nc4c(-c5ccc(F)cc5)nccc4[nH]2)nn3COCC[Si](C)(C)C)c1,,CN(C)C=O,,,,test
US20040152726A1,C[C@H](NC(=O)c1c(CBr)c(-c2ccccc2)nc2ccccc12)C1CCCCC1.O=C1NCCN1>>C[C@H](NC(=O)c1c(CN2CCNC2=O)c(-c2ccccc2)nc2ccccc12)C1CCCCC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05491152,BrC(Br)(Br)Br.CCCCCC1=C(CCCCC)CC(CO)SC1>>CCCCCC1=C(CCCCC)CC(CBr)SC1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20130245049A1,Cc1ccc(C(=O)CBr)cc1.N#CN=C1CCCN1>>Cc1ccc(C(=O)CN2CCCC2=NC#N)cc1,,CC#N,,[K],,test
US20160052884A1,COC(=N)C(Cl)(Cl)Cl.Nc1ccc([N+](=O)[O-])cc1N>>O=[N+]([O-])c1ccc2nc(C(Cl)(Cl)Cl)[nH]c2c1,,CC(=O)O,,CCOC(C)=O,O,test
US20160075653A1,CC(C)(C)OC(=O)NC1CC1(F)c1ccc(Cl)cc1.Cl>>Cl.NC1CC1(F)c1ccc(Cl)cc1,,CO,,,,test
US20140296231A1,Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1.NCC(O)Cc1ccc(F)cc1>>NCC(Cc1ccc(F)cc1)Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20050159599A1,CC(=O)Cl.O=C(c1c(F)cccc1F)N1CNCN(c2ccc(Cl)cc2)C1=O>>CC(=O)N1CN(C(=O)c2c(F)cccc2F)C(=O)N(c2ccc(Cl)cc2)C1,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US06159901,COC(=O)c1ccc(OC)c(Br)n1.Oc1cccc(C(F)(F)F)c1>>COc1ccc(C(=O)O)nc1Oc1cccc(C(F)(F)F)c1,I[Cu]I,CC(=O)N(C)C,,O,[H-].[Na+],test
US20150353559A1,N#Cc1ccc(C(=O)O)c(F)c1.OC1CCC1>>N#Cc1ccc(C(=O)O)c(OC2CCC2)c1,,CN(C)C=O,,[H-].[Na+],,test
US04491547,CCOCCO.FC(F)CC(=S)Cl>>CCOCCOC(=S)CC(F)F,,ClCCl,,c1ccncc1,,test
US20150291527A1,COC(=O)CC1CC1c1ccc(OC)c(F)c1>>COC(=O)CC1CC1c1ccc(O)c(F)c1,,ClCCl,,BrB(Br)Br,CO,test
US20040058819A1,C=O.N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1[S+]([O-])C(F)(F)F>>N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(NCO)c1S(=O)C(F)(F)F,,CO,,C[O-].[Na+],,test
US20070066820A1,Cc1ccc(S(=O)(=O)OC[C@H]2CCCN2C(=O)OC(C)(C)C)cc1.Sc1ccc(Oc2ccccc2)cc1>>CC(C)(C)OC(=O)N1CCC[C@@H]1CSc1ccc(Oc2ccccc2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04397847,C1=COCCC1.C1CCOC1.C[C@]12C(=CC[C@@H]3[C@@H]1CC[C@]1(C)C(=O)CC[C@@H]31)C[C@@H](O)C[C@@H]2O.ClCCl>>C[C@]12C(=CC[C@@H]3[C@@H]1CC[C@]1(C)C(=O)CC[C@@H]31)C[C@@H](OC1CCCCO1)C[C@@H]2OC1CCCCO1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100130495A1,CC(C)(C)OC(=O)N1CCC(=O)C(C(=O)Cc2ccccc2)C1.COc1cc(NC(=N)N)ccc1-n1cnc(C)c1>>COc1cc(Nc2nc3c(c(Cc4ccccc4)n2)CN(C(=O)OC(C)(C)C)CC3)ccc1-n1cnc(C)c1,,CCO,,C,C[O-].[Na+],test
US20050080110A1,O=C(CBr)c1ccccc1OCc1ccccc1.O=C[O-].[NH4+]>>c1ccc(COc2ccccc2-c2cocn2)cc1,,CN(C)C=O,O,CC(=O)[O-].[Na+],,test
US05935951,C=CCC(Cc1ccc([N+](=O)[O-])cc1)C(=O)O.OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>C=CCC(Cc1ccc([N+](=O)[O-])cc1)NC(=O)OCc1ccccc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20120184587A1,COc1c(C=O)cc(C(=O)O)cc1C(C)C.NO>>COc1c(C#N)cc(C(=O)O)cc1C(C)C,,O=CO,,Cl,,test
US20120071489A1,COC(=O)CCc1nc(-c2cc(Cl)cc(C(F)(F)F)c2)co1>>O=C(O)CCc1nc(-c2cc(Cl)cc(C(F)(F)F)c2)co1,,CO,,[Na+].[OH-],,test
US20120298966A1,Brc1cccc([Si](c2ccccc2)(c2ccccc2)c2cccc(Br)c2)c1.CC1(C)OB(c2cccc(C3=C4OC=C5C=CC=CC54CC=C3)c2)OC1(C)C>>Brc1cccc([Si](c2ccccc2)(c2ccccc2)c2cccc(-c3cccc(-c4cccc5c4oc4ccccc45)c3)c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[K+].[K+],,test
US04510139,COc1ccccc1N.O=C(O)c1ccccc1Cl>>COc1ccccc1Nc1ccccc1C(=O)O,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20160122358A1,NC(=O)c1c(-c2ccc(F)c(Cl)c2)nn2c1CNCC2.O=C(O)C1CC(F)(F)C1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>NC(=O)c1c(-c2ccc(F)c(Cl)c2)nn2c1CN(C(=O)NC1CC(F)(F)C1)CC2,,Cc1ccccc1,O,C1CCOC1,,test
US20090069297A1,COc1cnc2c(=O)cc[nH]c2c1.O=P(Cl)(Cl)Cl>>COc1cnc2c(Cl)ccnc2c1,,CCOC(C)=O,,[Ca+2].[Cl-].[Cl-],,test
US20070179115A1,NCc1ccc(-c2ccccc2)cc1.Nc1ncnc2c1nc(Br)n2[C@H]1C[C@H](O)[C@@H](CO)O1>>Nc1ncnc2c1nc(NCc1ccc(-c3ccccc3)cc1)n2[C@H]1C[C@H](O)[C@@H](CO)O1,,CCCO,,CCN(C(C)C)C(C)C,,test
US20030187023A1,Cc1cc(Cl)ccn1.O=C1CCNCC1>>Cc1cc(N2CCC(=O)CC2)ccn1,,CC(=O)O,,Cl,O,test
US20040092510A1,CC(=O)N1N=C(c2ccc([N+](=O)[O-])c(Cl)c2)c2cc(Cl)c(Cl)cc2CC1C>>CC(=O)N1N=C(c2ccc(N)c(Cl)c2)c2cc(Cl)c(Cl)cc2CC1C,[Ni],CO,ClCCl,NN,O,test
US20030199550A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H]1CC[C@H](OCCCCOCc2ccccc2)CC1.C[NH-]>>CN(C[C@@H]1CC[C@H](OCCCCO)CC1)C(=O)OC(C)(C)C,,C1COCCO1,O,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US05244908,CS(=O)(=O)Cl.NCCCCSc1cccc2nccn12>>CS(=O)(=O)NCCCCSc1cccc2nccn12,,ClCCl,,CCN(CC)CC,,test
US20110218197A1,CCOC(=O)c1c(C#N)c(C(C)(C)C)nn1C>>Cn1nc(C(C)(C)C)c(C#N)c1C(=O)O,,CO,,[Na+].[OH-],,test
US20060004046A1,CSC1=NC(=O)C(=Cc2ccc3ncc(S(C)(=O)=O)c(-c4ccccc4)c3c2)S1.N>>CS(=O)(=O)c1cnc2ccc(/C=C3\SC(N)=NC3=O)cc2c1-c1ccccc1,,CO,,,,test
US20160257658A1,CC(C)(C)OC(=O)N1CCNCC1.COC(=O)c1ccc(CBr)cc1>>COC(=O)c1ccc(CN2CCN(C(=O)OC(C)(C)C)CC2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090221635A1,CC(=O)O.O=C(O)c1nc2ccccc2cc1Oc1c(Cl)cc([N+](=O)[O-])cc1Cl>>COC(=O)c1ccc2ncc(Oc3c(Cl)cc([N+](=O)[O-])cc3Cl)cc2c1,,CCOCC,,C1CCOC1,,test
US20060173019A1,COCN(c1cc(Cl)cnc1C(=O)C1=C(C)C=CN(O)C1C)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1>>CC1=C(C(=O)c2ncc(Cl)cc2NS(=O)(=O)c2ccc(Cl)c(C(F)(F)F)c2)C(C)N(O)C=C1,,Cl,O,,,test
US06291679B1,COC(=O)C12CN(Cc3ccccc3)CC1C(I)=CCC2c1ccccc1.OB(O)c1cc2ccccc2s1>>COC(=O)C12CN(Cc3ccccc3)CC1C(c1cc3ccccc3s1)=CCC2c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US20130225646A1,CCOC(=O)C(CNC(=O)OCc1ccccc1)c1ccccc1C(F)(F)F>>CCOC(=O)C(CN)c1ccccc1C(F)(F)F,[Pd],CCO,,,,test
US20150291562A1,CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=S)N1c1ccc(O)cc1.Cc1ccc(S(=O)(=O)OCCCOCCOCCOCCNC(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)NCCOCCOCCOCCCOc1ccc(N2C(=S)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C2(C)C)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090143372A1,CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cnn(CCCl)c4)cc23)CC1.CNCCO>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cnn(CCN(C)CCO)c4)cc23)CC1,,C1CCOC1,,[I-].[Na+],,test
US04978665,CC(C)I.CCCOc1cc(CNc2c([N+](=O)[O-])n[nH]c(=O)c2Cl)ccc1OC>>CCCOc1cc(CNc2c([N+](=O)[O-])nn(C(C)C)c(=O)c2Cl)ccc1OC,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050009841A1,CC(C)(C)c1ccc(N=C=O)cc1.Clc1cccnc1N1CC2CCC(C1)N2>>CC(C)(C)c1ccc(NC(=O)N2C3CCC2CN(c2ncccc2Cl)C3)cc1,,ClCCl,,,,test
US05102893,CC(C)C(=O)CC(=O)c1ccc(F)cc1.NNc1cnccn1>>CC(C)c1cc(-c2ccc(F)cc2)n(-c2cnccn2)n1,,CC(=O)O,,,,test
US20080132503A1,CC(C)(C)OC(=O)Nc1ccc(-c2cccs2)cc1N.O=C(O)/C=C/c1ccc(N2CCOCC2)nc1>>CC(C)(C)OC(=O)Nc1ccc(-c2cccs2)cc1NC(=O)/C=C/c1ccc(N2CCOCC2)nc1,CN(C)c1ccncc1,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20120214837A1,COc1ccc2nc(NCC(F)(F)F)c(CO)cc2c1.O=S(Cl)Cl>>COc1ccc2nc(NCC(F)(F)F)c(CCl)cc2c1.Cl,,ClCCl,,,,test
US04007204,CC(=O)Cl.CCc1cc2ccccc2s1>>CCc1sc2ccccc2c1C(C)=O,,CC(Cl)Cl,,Cl,,test
US04933369,O=C1c2ccccc2C(=O)N1CCSCCCc1ccccc1>>NCCSCCCc1ccccc1,,CCO,,NN,O,test
US20110288066A1,CS(=O)(=O)Cl.OCc1ccc(F)c(Br)c1>>CS(=O)(=O)OCc1ccc(F)c(Br)c1,,ClCCl,,CCN(CC)CC,,test
US20080175794A1,CC(=O)c1nnccc1C(F)(F)F.Nc1nccc(Cl)c1C=O>>FC(F)(F)c1ccnnc1-c1ccc2c(Cl)ccnc2n1,,C1CCOC1,,,,test
US20150087675A1,Cc1ccc(C(N=[N+]=[N-])C2CCOCC2)o1>>Cc1ccc(C(N)C2CCOCC2)o1,[Pd],CCO,,[H][H],,test
US04072756,CC(=O)CCCBr.c1ccc2c(c1)COc1ccccc1C2=C1CCNCC1>>CC(=O)CCCN1CCC(=C2c3ccccc3COc3ccccc32)CC1,,ClC(Cl)Cl,,O=C([O-])[O-].[Na+].[Na+],,test
US04156079,COc1cccc(C=O)c1OCCCN1CCOCC1.NCCc1ccccc1>>COc1cccc(C=NCCc2ccccc2)c1OCCCN1CCOCC1,,Cc1ccccc1,,,,test
US20030153752A1,CC(C)(C)OC(=O)NCC(=O)O.Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)cn2C1CCC(O)C1>>CC(C)(C)OC(=O)NCC(=O)OC1CCC(n2cc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1,CN(C)c1ccncc1,CN(C)C=O,,CCN=C=NCCCN(C)C,Cl,test
US05496834,CC(=O)O[C@@H]1OCC[C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)c1ccc(NC(=O)OCc2ccccc2)cc1>>CC(=O)O[C@@H]1OCC[C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)c1ccc(N)cc1,[Pd],CCO,,,,test
US20100234351A1,CC(C)(C)NC(=O)c1cccc(Oc2ccc(Nc3ncnc4c3C=C(C=O)CCN4)cc2Cl)c1.CC(C)(C)ON>>CC(C)(C)NC(=O)c1cccc(Oc2ccc(Nc3ncnc4c3C=C(C=NOC(C)(C)C)CCN4)cc2Cl)c1,,CCO,,Cl,CC(=O)[O-].[Na+],test
US05021432,CC(C)(C)OC(=O)NN.CC1(C)Oc2ccc(C#N)cc2C2OC21>>CC(C)(C)OC(=O)NN[C@@H]1c2cc(C#N)ccc2OC(C)(C)[C@H]1O,,CCO,,,,test
US20140349993A1,CCOC(=O)c1cnc2ccc(Cl)nn12.OCCC(F)(F)F>>CCOC(=O)c1cnc2ccc(OCCC(F)(F)F)nn12,,CS(C)=O,,[H-].[Na+],,test
US20050192287A1,CNc1cc(OC)c(Oc2ccnc(NC(C)=O)c2)cc1[N+](=O)[O-]>>CNc1cc(OC)c(Oc2ccnc(NC(C)=O)c2)cc1N,[Pd],CO,,,,test
US20030176454A1,O=[N+]([O-])c1cccc(Nc2noc3c(Br)cccc23)c1>>Nc1cccc(Nc2noc3ccccc23)c1,[Pd],C1CCOC1,CO,[H][H],,test
US20030069242A1,CCCSc1cc(NN)ccc1C.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCCSc1cc(NNC(=O)C(F)(F)F)ccc1C,,c1ccncc1,,,,test
US20140288052A1,Br.CC(=O)c1ccccc1C(F)(F)F>>O=C(CBr)c1ccccc1C(F)(F)F,,ClC(Cl)Cl,,,,test
US03932403,CC(C)SCl.O=P(Nc1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)SN(c1ccccc1)P(=O)(c1ccccc1)c1ccccc1,,ClC(Cl)(Cl)Cl,,CCN(CC)CC,,test
US20110124665A1,COC(=O)CCBr.COc1ccc(-c2c(-c3ccccc3)oc3ncnc(OCC4CCCN4)c23)cc1>>COC(=O)CCN1CCCC1COc1ncnc2oc(-c3ccccc3)c(-c3ccc(OC)cc3)c12,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US04062862,COC=CCc1ccccc1.O=C(OO)c1ccccc1>>C=C(CC12C=CC=CC1O2)OCC,,ClC(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20130072467A1,C#CCNC1=NC(=O)OC1.O=CC1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1>>C#CCNC1=NC(=O)O/C1=C\C1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1,,CC(C)O,,C1CC[NH2+]CC1.CC(=O)[O-],,test
US20040048858A1,CC(=O)c1ccc(N)cc1.CCCCOc1c(OCCCC)c(=O)c1=O.N>>CC(=O)c1ccc(Nc2c(N)c(=O)c2=O)cc1,,CCO,,,,test
US05068325,ClCC=Cc1cccc(OCc2ccccc2)c1.Nc1nc2c(s1)CCNCC2>>Nc1nc2c(s1)CCN(CC=Cc1cccc(OCc3ccccc3)c1)CC2,,ClC(Cl)Cl,,CCOCC,,test
US20150315197A1,CC(C)(C)OC(=O)N1CCN(C(=O)Cl)CC1.O=C(c1n[nH]c2c1CNC2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1>>CC(C)(C)OC(=O)N1CCN(C(=O)N2Cc3[nH]nc(C(=O)N4CCC(c5ccc(F)c(F)c5C(F)(F)F)CC4)c3C2)CC1,CN(C)c1ccncc1,ClCCl,,Cl,,test
US20150065464A1,NC1CCC/C(=C\c2cccc(Oc3ccc(C(F)(F)F)cn3)c2)C1.O=C(O)c1cnccn1>>O=C(NC1CCC/C(=C\c2cccc(Oc3ccc(C(F)(F)F)cn3)c2)C1)c1cnccn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100029753A1,COC(=O)c1sccc1N.O=S(=O)(Cl)c1c(Cl)cc(C(F)(F)F)cc1Cl>>COC(=O)c1sccc1NS(=O)(=O)c1c(Cl)cc(C(F)(F)F)cc1Cl,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20140163000A1,CN(C(=O)OC(C)(C)C)C1CCN(c2ccncc2N)CC1>>CN(C)C1CCN(c2ccncc2N)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120004267A1,COC(=O)c1cc(NC(=O)c2cc(Br)ccn2)cs1.NN>>NNC(=O)c1cc(NC(=O)c2cc(Br)ccn2)cs1,,CCO,,O,,test
US20050107410A1,CC(C)(C)OC(=O)N1CCC(=Cc2cccc(I)c2)CC1.c1cn[nH]c1>>CC(C)(C)OC(=O)N1CCC(=Cc2cccc(-n3cccn3)c2)CC1,[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20070167406A1,CCOC(=O)/C(C#N)=C\c1ccc(C#N)cc1.CCOC(=O)/C=C(/Nc1cncc(C(F)(F)F)c1)C(F)(F)F>>CCOC(=O)C1=C(N)N(c2cncc(C(F)(F)F)c2)C(C(F)(F)F)=C(C(=O)OCC)C1c1ccc(C#N)cc1,,C1COCCO1,,C1CCC2=NCCCN2CC1,,test
US04922021,CCNCC.Cc1cccc(C)c1N(CC(C)OS(C)(=O)=O)S(C)(=O)=O>>CCN(CC)C(C)CN(c1c(C)cccc1C)S(C)(=O)=O,,CCOCC,,,,test
US20060211737A1,CC1(C)CC(=O)c2c(C(F)(F)F)n[nH]c2C1.N#Cc1ccc(F)cc1NCC(O)CO>>CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3ccc(C#N)c(NCC(O)CO)c3)c2C1,,CC(=O)N(C)C,,[H-].[Na+],[Cl-].[NH4+],test
US20150175572A1,COC(=O)c1c(OCCNC(=O)OC(C)(C)C)cnc(OC(C)C)c1C>>COC(=O)c1c(OCCN)cnc(OC(C)C)c1C,,ClCCl,,O=C(O)C(F)(F)F,,test
US03963706,COC(=O)Cl.NS(=O)(=O)c1ccc(NC(=O)CNc2ccccc2)cc1>>COC(=O)N(CC(=O)Nc1ccc(S(N)(=O)=O)cc1)c1ccccc1,,CCOC(C)=O,,,,test
US05099083,COCCl.c1ccc2c(c1)CC2>>ClCc1cccc2c1CC2,,ClCCl,,Cl[Sn](Cl)(Cl)Cl,,test
US20050014812A1,CCCCCOc1ccc(CBr)c(Cl)c1.CCOC(=O)CCCCCOc1cccc(N)c1NC(C)=O>>CCCCCOc1ccc(CNc2cccc(OCCCCCC(=O)OCC)c2NC(C)=O)c(Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05514680,Nc1cc(C(F)(F)F)c(F)cc1[N+](=O)[O-]>>Nc1cc(F)c(C(F)(F)F)cc1N,[Pd],CCO,,,,test
US20150376206A1,COc1ccc2cc1Cn1c(nc3ccccc31)NC(=O)c1cccc(c1)Cn1nc-2ccc1=O>>O=C1Nc2nc3ccccc3n2Cc2cc(ccc2O)-c2ccc(=O)n(n2)Cc2cccc1c2,,ClCCl,,,,test
US06566366B1,CC(C)(C)OC(=O)[C@H](CNC(=O)c1ccc(CCC(=O)NC2=NCCCN2)s1)NS(=O)(=O)c1ccc(C(F)(F)F)cc1>>O=C(CCc1ccc(C(=O)NC[C@H](NS(=O)(=O)c2ccc(C(F)(F)F)cc2)C(=O)O)s1)NC1=NCCCN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110028492A1,FC(F)(F)[C@H]1CO1.N[C@@H]1CC[C@@H](Nc2cc(-c3cccc(NCC4CCOCC4)n3)c(Cl)cn2)CC1>>O[C@H](CN[C@@H]1CC[C@@H](Nc2cc(-c3cccc(NCC4CCOCC4)n3)c(Cl)cn2)CC1)C(F)(F)F,,CC(C)O,,,,test
US20090215725A1,CN(C)C1(C#N)CCC(COCC#C[Si](C)(C)C(C)(C)C)CC1.Cl[Mg]c1ccccc1>>CN(C)C1(c2ccccc2)CCC(COCC#C[Si](C)(C)C(C)(C)C)CC1,,C1CCOC1,,O,[Cl-].[NH4+],test
US05786374,CCc1noc2ccccc12.O=C1CCC(=O)N1Br>>CC(Br)c1noc2ccccc12,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20060160904A1,CN.Cl.O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(C[C@H]2CO2)ccc1Cl>>CNC[C@@H](O)Cc1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1.Cl,,ClCCl,,C1CCOC1,,test
US20130317001A1,CC(C)(C)OC(=O)c1cc(C2CC2)c(OCC23CCC(=O)CC2C3)cc1F>>CC(C)(C)OC(=O)c1cc(C2CC2)c(OCC23CCC(O)CC2C3)cc1F,,COCCOC,,[BH4-].[Na+],,test
US20080096877A1,CCN=C=NCCCN(C)C.COc1ccccc1S(=O)(=O)N(C)c1cccc2cc(C3=NCC(CC(=O)O)S3)[nH]c12>>COc1ccccc1S(=O)(=O)N(C)c1cccc2cc(C3=NCC(CC(N)=O)S3)[nH]c12,,CCOC(C)=O,,CN(C)C=O,Cl,test
US20110152318A1,C=C(C)c1cc(O)cc(C(F)(F)F)c1>>CC(C)c1cc(O)cc(C(F)(F)F)c1,[Pd],CCOC(C)=O,CO,[H][H],,test
US04652584,CC(C)(O)C#Cc1cc(Cl)cc(Cl)c1>>C#Cc1cc(Cl)cc(Cl)c1,,Cc1ccccc1,,[Na+].[OH-],,test
US20150266857A1,CS(=O)(=O)Cl.O=S(=O)(c1ccccc1)n1cc(-c2ccc3nc(CC4CCNCC4)oc3c2)c2ccc(F)cc21>>CS(=O)(=O)N1CCC(Cc2nc3ccc(-c4cn(S(=O)(=O)c5ccccc5)c5cc(F)ccc45)cc3o2)CC1,,ClCCl,,O,,test
US20120157435A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Clc1cc(Br)cc2c1Nc1c(Cl)cc(Br)cc1S2>>CC(C)(C)OC(=O)N1c2c(Cl)cc(Br)cc2Sc2cc(Br)cc(Cl)c21,CN(C)c1ccncc1,CC#N,,,,test
US20150299123A1,Brc1csc(Br)n1.COC(=O)C1CCNCC1>>COC(=O)C1CCN(c2nc(Br)cs2)CC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US04542142,CC(OC(=O)[C@@H]1[C@H](C#CC(=O)OCC(Cl)(Cl)Cl)C1(C)C)c1cccc(Oc2ccccc2)c1>>C[C@@H](OC(=O)[C@@H]1[C@H](C#CC(=O)O)C1(C)C)c1cccc(Oc2ccccc2)c1,[Zn],ClCCl,,CC(=O)O,O,test
US05612373,CC(C)(C)OC(=O)NCc1ccc(C(=O)O)cc1.NNC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NCc1ccc(C(=O)NNC(=O)OCc2ccccc2)cc1,,C1CCOC1,,CC(C)COC(=O)Cl,CCN(CC)CC,test
US04379166,CC(=O)CCOCc1ccccc1.CS(=O)c1cc(C(O)CN)ccc1O>>CC(CCOCc1ccccc1)NCC(O)c1ccc(O)c(S(C)=O)c1,,CO,,[BH3-]C#N.[Na+],,test
US20100256092A1,COCOCC(c1ccccc1)c1ccccc1B1OC(C)(C)C(C)(C)O1>>OB1OCC(c2ccccc2)c2ccccc21,,CO,,Cl,,test
US20140275070A1,CC1(C)C=NC(N2CCNCC2)S1.FC(F)(F)Cc1cc2c(Cl)ncnc2s1>>CC1(C)CN=C(N2CCN(c3ncnc4sc(CC(F)(F)F)cc34)CC2)S1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20070027160A1,CCOC(=O)N1CCNCC1.O=C1COc2ccc(F)cc21>>CCOC(=O)N1CCN(c2coc3ccc(F)cc23)CC1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20030007927A1,CCOC(=O)CCCCn1nnc(C(C)(C)CCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)n2)n1>>CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnn(CCCCC(=O)O)n1,,C1CCOC1,,[Li+].[OH-],,test
US20150133424A1,O=C1CCN(C(=O)c2cccc([N+](=O)[O-])c2)CC1>>O=C(c1cccc([N+](=O)[O-])c1)N1CCC(O)CC1,,C1CCOC1,O,CO,[BH4-].[Na+],test
US05464607,C1=COCCC1.O=C(CCl)NCC(O)CNC(=O)CCl>>O=C(CCl)NCC(CNC(=O)CCl)OC1CCCCO1,,ClCCl,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20030092720A1,COS(=O)(=O)OC.COc1ccc(Cn2nnc(-c3c(O)nc4cc(CCc5nc(C(C)C)cs5)ccn4c3=O)n2)cc1>>COc1ccc(Cn2nnc(-c3c(OC)nc4cc(CCc5nc(C(C)C)cs5)ccn4c3=O)n2)cc1,,CN(C)C=O,,CCN(CC)CC,O,test
US20040204427A1,COc1ccc(Nc2ncc3c(n2)N([C@@H]2CC[C@@H](O[Si](C)(C)C(C)(C)C)CC2)C(=O)N(c2ccc(OC)cc2)C3)cc1>>COc1ccc(Nc2ncc3c(n2)N([C@@H]2CC[C@@H](O)CC2)C(=O)N(c2ccc(OC)cc2)C3)cc1,,CCOC(C)=O,ClCCl,O=C(O)C(F)(F)F,,test
US20150329535A1,CC(C)(C)[Si](C)(C)OCCCCCCOc1ccc(-c2ccccc2)c([N+](=O)[O-])c1>>CC(C)(C)[Si](C)(C)OCCCCCCOc1ccc(-c2ccccc2)c(N)c1,[Pd],CO,,[H][H],,test
US20030166639A1,CC(C)(C)OC(=O)Nc1ccc(-c2ccccc2F)cc1NC(=O)CC(=O)c1cccc(-c2ccncc2)c1>>O=C1CC(c2cccc(-c3ccncc3)c2)=Nc2ccc(-c3ccccc3F)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140155407A1,CC(C)C(O)c1ccc(-c2ccccc2)nc1.O=C(n1ccnc1)n1ccnc1>>CC(C)C(c1ccc(-c2ccccc2)nc1)n1ccnc1,,CN1CCCC1=O,,,,test
US04576746,CCC1C(=O)NC1CCOC(C)=O>>CCC1C(=O)NC1CCO,,CO,,CC(=O)O,O=C([O-])[O-].[K+].[K+],test
US20010039285A1,COc1ccc2c(c1)CCN=C2c1ccc(I)cc1>>COc1ccc2c(c1)CCNC2c1ccc(I)cc1,,CO,,Cl,[BH4-].[Na+],test
US20110052699A1,CC(C)=O.CCO.C[C@]12CCC(=O)C=C1[C@@H]1C[C@@H]1[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1[C@@H]1C[C@@H]1[C@@]21CCC(=O)O1>>C=C(C)C(=O)OC.C[C@]12CCC(=O)C=C1[C@@H]1C[C@@H]1[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1[C@@H]1C[C@@H]1[C@@]21CCC(=O)O1,,CC(C)=O,,,,test
US20090018336A1,CN1CCN(C(=O)OC2c3nccnc3C(=O)N2c2ccc(Cl)cn2)CC1>>CN1CCN(C(=O)O[C@H]2c3nccnc3C(=O)N2c2ccc(Cl)cn2)CC1,,O,,,,test
US20090042964A1,CCCCBr.CN1C(=O)C(c2cccc(O)c2)(c2ccc(OC(F)F)c(Cl)c2)N=C1N>>CCCCOc1cccc(C2(c3ccc(OC(F)F)c(Cl)c3)N=C(N)N(C)C2=O)c1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05684151,O=[N+]([O-])c1ccc(S(=O)(=O)N2CCCC(c3ccc(Cl)cc3)=N2)cc1>>Nc1ccc(S(=O)(=O)N2CCCC(c3ccc(Cl)cc3)=N2)cc1,[Fe],CC(=O)O,,,,test
US04959393,CCCCCC(=O)c1c(O)cccc1O>>CCCCCCc1c(O)cccc1O,[Zn],Cc1ccccc1,,Cl,O,test
US20060264460A1,CC(C)(C)OC(=O)N1CCCC(C=O)C1.N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1>>CC(C)(C)OC(=O)N1CCCC(CNc2ccc3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)C1,,CCO,,[BH3-]C#N.[Na+],,test
US20110144066A1,CCCCCCCCc1ccccc1.O=S(=O)(O)Cl>>CCCCCCCCc1ccc(S(=O)(=O)Cl)cc1,,ClC(Cl)Cl,,,,test
US20130245042A1,NNc1nccc(NC[C@H]2C[C@@H]2c2ccc(F)cc2)c1C(F)(F)F.O=C(Cl)CC(F)(F)F>>O=C(CC(F)(F)F)NNc1nccc(NC[C@H]2C[C@@H]2c2ccc(F)cc2)c1C(F)(F)F,,C1CCOC1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US20020099212A1,COC(=O)c1ccc(C(=O)OC)c(N)c1.ClCc1ccc(Cl)cc1Cl>>COC(=O)c1ccc(C(=O)OC)c(NCc2ccc(Cl)cc2Cl)c1,,Cc1ccccc1,O,[I-].[K+],,test
US06479519B1,COC(=S)Cc1ccc([N+](=O)[O-])cn1>>COC(=S)Cc1ccc(N)cn1,[Fe],O,,CCO,[Cl-].[NH4+],test
US20160264547A1,CN[C@@H](C)C(=O)O.O=C(Nc1cc(C(F)(F)F)ccn1)Oc1ccc([N+](=O)[O-])cc1>>C[C@H]1C(=O)N(c2cc(C(F)(F)F)ccn2)C(=O)N1C,,CCOC(C)=O,,C1COCCO1,,test
US20060276504A1,CC(=O)c1cc(F)ccc1S.CC(C)(C)C(=O)CBr>>Cc1c(C(=O)C(C)(C)C)sc2ccc(F)cc12,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110263873A1,CCOC(=O)/C(C)=C/C(C)O.CCOP(=O)(Cl)OCC>>CCOC(=O)/C(C)=C/C(C)OP(=O)(OCC)OCC,,c1ccncc1,,,,test
US20150329523A1,COc1cc(N)cc(S(=O)(=O)C2CC2)c1.COc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)cn1>>COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)nn4-c4ccc(OC)nc4)c4ccccc34)n2)cc(S(=O)(=O)C2CC2)c1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20100190824A1,CCOC(=O)CC(=O)N(Cc1ccccc1)CC(C(=O)OCC)c1ccccc1>>CCOC(=O)C1C(=O)C(c2ccccc2)CN(Cc2ccccc2)C1=O,,CCO,O,Cl,CC(C)(C)[O-].[K+],test
US04166119,COc1cc(C(=O)Cl)cc(OC)c1OC.c1ccc2c(c1)CC1(CCNCC1)O2>>COc1cc(C(=O)N2CCC3(CC2)Cc2ccccc2O3)cc(OC)c1OC,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20090203750A1,O.O=C(NC(CO)c1ccccc1)[C@@H]1C[C@H]1c1ccccc1>>O=C(O)[C@@H]1C[C@H]1c1ccccc1,,C1COCCO1,,,,test
US20080153810A1,Nc1ccc2[nH]nc(-c3ncco3)c2c1.O=C(O)Cc1ccc(Oc2ccccc2)cc1.On1nnc2ccccc21>>O=C(Cc1ccc(OCc2ccccc2)cc1)Nc1ccc2[nH]nc(-c3ncco3)c2c1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,ClCCCl,test
US20090117125A1,CC(=O)N1Cc2ccccc2CC1C(=O)O.COC(=O)C#CC(=O)OC>>COC(=O)c1c(C(=O)OC)c2n(c1C)Cc1ccccc1C2,,CC(=O)OC(C)=O,,,,test
US20040092737A1,COCN1c2cc(CCl)ccc2Sc2nccnc21.c1cn[nH]c1>>COCN1c2cc(Cn3cccn3)ccc2Sc2nccnc21,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20080275067A1,C1COCCN1.COC(=O)c1c(CBr)cccc1[N+](=O)[O-]>>COC(=O)c1c(CN2CCOCC2)cccc1[N+](=O)[O-],,CN(C)C=O,O,[I-].[K+],,test
US20040092598A1,C1CCOC1.CC(=C\c1ccccc1)/C=C/C(=O)Cl.CCN(CC)CC.O=C(O)/C=C/C=C/c1ccccc1>>COC(=O)CCCCCNC(=O)/C=C/C=C/c1ccccc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20090023789A1,COc1ccc(Cl)cc1C(=O)/N=c1\sn(C(C)(C)C)cc1CCN=[N+]=[N-]>>COc1ccc(Cl)cc1C(=O)/N=c1\sn(C(C)(C)C)cc1CCN,[Pd],CCO,,,,test
US20110212103A1,CC(O)CNC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(F)cc1O>>CC(CNC(=O)OC(C)(C)C)Oc1cc(F)ccc1[N+](=O)[O-],,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04279912,CCOC(=O)C(=O)CBr.COc1ccc2c(Cl)cc(N)nc2c1>>CCOC(=O)c1cn2c(cc(Cl)c3ccc(OC)cc32)n1,,COCCOC,,,,test
US20050250926A1,C=Cc1ccc(C(=O)Cl)cc1.OCC1COC(=S)N1>>C=Cc1ccc(C(=O)OCC2COC(=S)N2)cc1,,C1CCOC1,,c1ccncc1,,test
US20090042949A1,CC(C)(C)c1ccc(-c2ccc3c(c2)cc(C(=O)Cl)n3-c2ccc(OC3CCCC3)cc2)cc1.CS(N)(=O)=O>>CC(C)(C)c1ccc(-c2ccc3c(c2)cc(C(=O)NS(C)(=O)=O)n3-c2ccc(OC3CCCC3)cc2)cc1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20100234365A1,Cc1ccc(S(=O)(=O)N2C[C@H](c3cccc(C(F)(F)F)c3)N(c3ccc(Oc4ccc(Cl)cc4)cc3)C2=NC#N)cc1>>N#CN=C1NC[C@H](c2cccc(C(F)(F)F)c2)N1c1ccc(Oc2ccc(Cl)cc2)cc1,,CO,,[Mg],,test
US20060160803A1,Clc1ccnc(Cl)n1.O=C(CCc1cccc(O)c1)Nc1ccc(Cl)c(C(F)(F)F)c1>>O=C(CCc1cccc(Oc2ccnc(Cl)n2)c1)Nc1ccc(Cl)c(C(F)(F)F)c1,,C1CCOC1,O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20060063759A1,CS(=O)(=O)Nc1cccc(C=C2c3ccccc3CCc3ccc(Cl)cc32)c1>>CS(=O)(=O)Nc1cccc(CC2c3ccccc3CCc3ccc(Cl)cc32)c1,[Pt],CCOC(C)=O,,,,test
US06262045B1,CCOC(=O)C(=O)Cl.CCOC(=O)c1cc2cc(F)ccc2[nH]1>>CCOC(=O)C(=O)c1c(C(=O)OCC)[nH]c2ccc(F)cc12,Cl[Ti](Cl)(Cl)Cl,ClCCl,,O,,test
US04322414,CCCCSP(=S)(Cl)Oc1ccc(C(F)(F)F)cc1.O=C1CCc2cccc(O)c21>>CCCCSP(=S)(Oc1ccc(C(F)(F)F)cc1)Oc1cccc2c1C(=O)CC2,,Cc1ccccc1,,CCN(CC)CC,,test
US20090018122A1,CC(=O)Cl.CCOCc1nc2cnc3cc(OCc4ccccc4)ccc3c2n1CC(C)(C)N>>CCOCc1nc2cnc3cc(OCc4ccccc4)ccc3c2n1CC(C)(C)NC(C)=O,,ClCCl,,CCN(CC)CC,,test
US20070015743A1,Fc1cccc2ncnc(Cl)c12.Nc1ccc(OCc2ccccn2)c(Cl)c1>>Fc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12,,CC(C)O,,,,test
US20110218192A1,N#Cc1cccc(B(O)O)c1.O=C1CC2(CCOCC2)Oc2ccc(Br)cc21>>N#Cc1cccc(-c2ccc3c(c2)C(=O)CC2(CCOCC2)O3)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110218197A1,CC(C)(C)c1cc(C(=O)Nc2c(N)cc(-c3ccccc3C(F)(F)F)nc2Cl)on1>>CC(C)(C)c1cc(-c2nc3cc(-c4ccccc4C(F)(F)F)nc(Cl)c3[nH]2)on1,,CC(=O)O,,O,,test
US20120094972A1,CC(=O)N1CCS(=O)(=O)c2ccc([N+](=O)[O-])cc21>>CC(=O)N1CCS(=O)(=O)c2ccc(N)cc21,,CCOC(C)=O,,O=C([O-])O.[Na+],,test
US20160095858A1,CC(=O)n1cc(C)c(OCC(C)C)n1>>Cc1c[nH]nc1OCC(C)C,,CO,,[Na+].[OH-],,test
US20140252279A1,CCCCCCCCCC(CCCCCCC)C(=O)O.O=C(Cl)C(=O)Cl>>CCCCCCCCCC(CCCCCCC)C(=O)Cl,,ClCCl,,CN(C)C=O,,test
US06372770B1,COc1ccc(Cc2nc3cc(Cl)cc(CCCO)c3o2)cc1OC>>COc1ccc(Cc2nc3cccc(CCCO)c3o2)cc1OC,[Pd],C1CCOC1,,CCN(CC)CC,,test
US20040254181A1,COC(C)(OC)C(C#N)=Cc1ccccc1>>CC(=O)C(C#N)=Cc1ccccc1,,Cl,,CCCCCC,CCOC(C)=O,test
US20110313151A1,Cl.ClCCl.O=C([O-])NC1CCC(CCN2CCN(c3nccc4c3CCO4)CC2)CC1>>Cl.Cl.Cl.N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4c3CCO4)CC2)CC1,,ClCCl,,,,test
US20100168196A1,CC(C)Br.Clc1cccc(Cl)c1Nc1nc2ccccc2[nH]1>>CC(C)N(c1nc2ccccc2[nH]1)c1c(Cl)cccc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20160137653A1,II.OC[C@H]1CC[C@@H](c2ccccc2)CC1>>IC[C@H]1CC[C@@H](c2ccccc2)CC1,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080085890A1,CO/C=C1/C(=O)NC(=O)c2ccc(C(C)(C)C)cc21.NCc1cc(O)c(-c2ccoc2)cn1>>CC(C)(C)c1ccc2c(c1)C(=CNCc1cc(O)c(-c3ccoc3)cn1)C(=O)NC2=O,,CN(C)C=O,,,,test
US20080287409A1,COc1cc(OCc2sc(-c3ccc(C(F)(F)F)cc3)nc2CCCOCc2ccccc2)ccc1C#N.NO>>COc1cc(OCc2sc(-c3ccc(C(F)(F)F)cc3)nc2CCCOCc2ccccc2)ccc1C(=N)NO,,C1CCOC1,CO,CCN(CC)CC,Cl,test
US05739345,CI.OCCCc1nc2cccnc2[nH]1>>Cn1c(CCCO)nc2cccnc21,,CN(C)C=O,,[H-].[Na+],,test
US20050059710A1,C=Cc1ccc(Nc2c(C(O)CO[Si](C(C)C)(C(C)C)C(C)C)ccc(F)c2F)c(F)c1>>CCc1ccc(Nc2c(C(O)CO[Si](C(C)C)(C(C)C)C(C)C)ccc(F)c2F)c(F)c1,,C1CCOC1,,[H][H],,test
US07169951B2,C=CCOC(=O)Cc1cccc(S(=O)(=O)N=C=O)c1.Nc1cc(Cl)ccc1C(=O)O>>C=CCOc1cccc(S(=O)(=O)n2c(=O)[nH]c3cc(Cl)ccc3c2=O)c1C=C=O,,C1CCOC1,,O,,test
US20130261106A1,CC(C)I.O=Cc1ccc([N+](=O)[O-])c(O)c1>>CC(C)Oc1cc(C=O)ccc1[N+](=O)[O-],,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030064991A1,Cc1[nH]c2ccc(CCOS(C)(=O)=O)cc2c1C(=O)OCc1ccccc1.OC[C@H]1CCCN1>>Nc1cc2ccccc2[nH]1,,C1COCCO1,,,,test
US20110263598A1,O=C1C(=O)N(Cc2ccccc2)c2ccc(F)cc21>>O=C1Cc2cc(F)ccc2N1Cc1ccccc1,,CCCCCC,,CCOCC,,test
US20130261086A1,COB1OC(C)(C)C(C)(C)O1.FC(F)(COCc1ccccc1)Cn1cc(I)cn1>>CC1(C)OB(c2cnn(CC(F)(F)COCc3ccccc3)c2)OC1(C)C,,C1CCOC1,,CC(C)[Mg]Cl,[Cl-].[NH4+],test
US20100210619A1,Cc1cc(S(N)(=O)=O)ccc1N.O=C(Cl)c1cc(Cl)ncn1>>Cc1cc(S(N)(=O)=O)ccc1NC(=O)c1cc(Cl)ncn1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20050043331A1,COC(=O)c1c(-c2ccc(F)cc2)c(-c2ccncc2)cn1C.O=C1CCC(=O)N1Br>>COC(=O)c1c(-c2ccc(F)cc2)c(-c2ccncc2)c(Br)n1C,,ClCCl,,CCOCC,,test
US20050026968A1,Nc1cccc(N2CCOCC2)c1.O=C(Cl)c1ccc([N+](=O)[O-])o1>>O=C(Nc1cccc(N2CCOCC2)c1)c1ccc([N+](=O)[O-])o1,,ClCCl,,CCN(CC)CC,,test
US05186717,COS(=O)(=O)[O-].Cc1ccc(S(=O)(=O)Nc2cc(C)cc([N+](=O)[O-])c2N)cc1>>Cc1ccc(S(=O)(=O)N(C)c2cc(C)cc([N+](=O)[O-])c2N)cc1,,[Na+],[OH-],,,test
US20120020884A1,BrCCOCc1ccccc1.Nc1ccccc1>>c1ccc(COCCNc2ccccc2)cc1,,CCOC(C)=O,CN(C)C=O,Cc1cccc(C)n1,,test
US20070238778A1,COC(=O)C(=CN(C)C)NC(=O)c1ccccc1.Nc1ccccc1>>COC(=O)C(=CNc1ccccc1)NC(=O)c1ccccc1,,CC(C)O,,Cl,O,test
US20010034343A1,CC(C)(C)[Si](C)(C)Cl.COC(=O)c1cc(O)ccc1O>>COC(=O)c1cc(O[Si](C)(C)C(C)(C)C)ccc1O,,ClCCl,,c1c[nH]cn1,,test
US20130338139A1,COc1ccc(CCl)cc1.O=Cc1cc2c([nH]c(=O)n3nccc23)s1>>COc1ccc(Cn2c(=O)n3nccc3c3cc(C=O)sc32)cc1,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20130158188A1,CCCCCO.O=C(O)CN1C(=O)C=CC1=O>>CCCCCOC(=O)CN1C(=O)C=CC1=O,,O,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US20100048604A1,C#Cc1cc(=O)oc2c3c4c(cc12)CCCN4CCC3.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CN(C)c1ccc2c(OS(=O)(=O)C(F)(F)F)cc(=O)oc2c1,,ClCCl,,CCN(CC)CC,,test
US20100197681A1,NC1CCCCC1.Nc1nc2cccc(Cl)n2n1>>Nc1nc2cccc(NC3CCCCC3)n2n1,,COC(C)(C)C,,,,test
US05629254,CC(C)CC1Cc2c(Br)cccc2C1O.C[Si](C)(C)Cl>>CC(C)CC1Cc2c(Br)cccc2C1O[Si](C)(C)C,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20130085142A1,COC(=O)CN1C[C@H](Oc2cnc(C3CC3)cn2)C[C@H]1CN=[N+]=[N-]>>O=C1CN2C[C@H](Oc3cnc(C4CC4)cn3)C[C@H]2CN1,[Ni],CO,,O,,test
US20120053148A1,CON(C)C(=O)c1ccnc(CNC(=O)c2cc(C)c3cc(C4CC4)cc(C(F)(F)F)c3n2)c1>>Cc1cc(C(=O)NCc2cc(C=O)ccn2)nc2c(C(F)(F)F)cc(C3CC3)cc12,,CCO,,,,test
US20020016328A1,CCC(CC)Nc1cc(C)nc(Oc2c(C)cc(C)cc2C)c1C(=O)n1ccnc1.C[Mg]Br>>CCC(CC)Nc1cc(C)nc(Oc2c(C)cc(C)cc2C)c1C(C)=O,,ClCCl,,CCOCC,,test
US20160024142A1,COC(=O)c1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3cncc(C#N)c3)=CC[C@@H]12>>C[C@]12CC[C@@H]3c4ccc(C(=O)O)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(C#N)c1,,C1CCOC1,CO,[Li+].[OH-],,test
US20110319436A1,Nc1ccc(Nc2nccc(Nc3cc(C4CC4)n[nH]3)n2)cc1.O=C=Nc1cccc(C(F)(F)F)c1>>O=C(Nc1ccc(Nc2nccc(Nc3cc(C4CC4)n[nH]3)n2)cc1)Nc1cccc(C(F)(F)F)c1,,ClCCl,,,,test
US20060276464A1,O=C(OC(=O)C(F)(F)F)C(F)(F)F.O=S(=O)(NC1CCNCC1)c1cc(S(=O)(=O)c2ccccc2)ccc1Cl>>O=C(N1CCC(NS(=O)(=O)c2cc(S(=O)(=O)c3ccccc3)ccc2Cl)CC1)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20100210636A1,Br[Mg]C1CC1.N#Cc1cc(Cl)ccc1N.O=C([O-])O>>Nc1ccc(Cl)cc1C(=O)C1CC1,,C1CCOC1,CCOC(C)=O,Cl,,test
US06958330B1,CC(C)(C)OC(=O)NN1C(=O)Cc2ccccc2-c2ccccc21.COC(=O)CBr.ClCCl>>COC(=O)CC1C(=O)N(N)c2ccccc2-c2ccccc21.Cl,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070010511A1,COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2OCc2ccc(O)c(N)c2)cc1.O=C(Cl)Oc1ccccc1>>COc1ccccc1COCCCOc1ccc([C@H]2CCN(C(=O)OC(C)(C)C)C[C@@H]2OCc2ccc3oc(=O)[nH]c3c2)cc1,,CO,O,Cl,[Na+].[OH-],test
US20150038437A1,CC(C)(C)OC(=O)c1c(OC(C)(C)C)nc(I)c(Cl)c1OC(C)(C)C.Cn1ccc2cc(B(O)O)ccc21>>Cn1ccc2cc(-c3nc(OC(C)(C)C)c(C(=O)OC(C)(C)C)c(OC(C)(C)C)c3Cl)ccc21,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US07361766B2,O=[N+]([O-])c1cnc2nn(-c3ccccc3)cc2c1>>Nc1cnc2nn(-c3ccccc3)cc2c1,[Pd],CCOC(C)=O,CO,,,test
US20070037739A1,CC(=O)Cl.COc1cc(C(C)=O)ccc1O>>COc1cc(C(C)=O)ccc1OC(C)=O,,CCOC(C)=O,,CCN(CC)CC,,test
US20020193382A1,CC(C)(C)OC(=O)N1CCNC(=O)C1.COC(=O)C=CC1CCN(C(=O)OCc2ccccc2)CC1>>COC(=O)CC(C1CCN(C(=O)OCc2ccccc2)CC1)N1CCN(C(=O)OC(C)(C)C)CC1=O,,C1CCOC1,CCOC(C)=O,CC(C)(C)[O-].[K+],,test
US04883797,C1CCNCC1.C=C(CCl)CN1CCN(C(c2ccccc2)c2ccccc2)CC1>>C=C(CN1CCCCC1)CN1CCN(C(c2ccccc2)c2ccccc2)CC1,,CCO,,O,,test
US20160157491A1,OC1CCCc2cc(Br)ccc21>>Brc1ccc2c(c1)CCC=C2,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090221575A1,CCC#CCC(C)(C)CO>>CCC#CCC(C)(C)C=O,,ClCCl,O,CS(C)=O,O=C(Cl)C(=O)Cl,test
US20090186879A1,CC(=O)O.CC=O.Nc1ccc(Cl)c2nc3n(c12)CCCCN3c1ccc(Cl)cc1Cl>>CCN(CC)c1ccc(Cl)c2nc3n(c12)CCCCN3c1ccc(Cl)cc1Cl,,CC(=O)O,CO,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20160024044A1,CCOC(=O)NCC(c1ccc(Cl)cc1)C(O)c1ccccc1>>CNCC(c1ccc(Cl)cc1)C(O)c1ccccc1,,C1CCOC1,CCOCC,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120149691A1,N#Cc1cnn2cccc2c1Cl.NC1(c2ccc(Cl)cc2Cl)CC1>>N#Cc1cnn2cccc2c1NC1(c2ccc(Cl)cc2Cl)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20130274255A1,COc1ccc(-c2nn(COCC[Si](C)(C)C)c3c2Cc2sc(-c4ccoc4)cc2-3)cc1>>COc1ccc(-c2n[nH]c3c2Cc2sc(-c4ccoc4)cc2-3)cc1,,CO,,Cl,,test
US04044148,O=[N+]([O-])c1cc(-c2ccccc2)c(Cl)c([N+](=O)[O-])c1>>Nc1cc(N)c(Cl)c(-c2ccccc2)c1,[Ni],C1COCCO1,,[H][H],,test
US20030105336A1,NNC(=O)c1ccccc1.O=C(O)c1ccc(C(=O)c2ccccc2F)o1>>O=C(O)c1ccc(-c2n[nH]c3ccccc23)o1,CC(=O)O,CCO,,CC(C)(C)[O-].[K+],,test
US20070105872A1,CI.Oc1c(Cl)cc(Cl)cc1Br>>COc1c(Cl)cc(Cl)cc1Br,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US05891897,COC(=O)OC.N#CCc1nc(-c2c(F)cccc2F)cs1>>COC(=O)C(C#N)c1nc(-c2c(F)cccc2F)cs1,,Cc1ccccc1,,Cl,C[O-].[Na+],test
US20120114739A1,CC(NC1CCOCC1)c1cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n2nccc2n1.O=C1CCC(=O)N1I>>CC(NC1CCOCC1)c1cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n2ncc(I)c2n1,,CC#N,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20150210698A1,Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CCC(N)CC1.O=C(O)c1cccnc1>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2[C@@H]1CC[C@@H](NC(=O)c2cccnc2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US06506744B1,Nc1ccc2c(c1)C(=O)N(CC(=O)NC(CC(=O)O)c1ccccc1)[C@@H](CCC(=O)O)C(=O)N2.O=C=NCc1ccccc1>>O=C(O)CC[C@H]1C(=O)Nc2ccc(NC(=O)NCc3ccccc3)cc2C(=O)N1CC(=O)NC(CC(=O)O)c1ccccc1,,CN(C)C=O,,,,test
US05446189,CCCCCCCCCCCCCCCCCCOc1cccc(N)c1.O=C(CBr)OCc1ccccc1>>CCCCCCCCCCCCCCCCCCOc1cccc(NCC(=O)OCc2ccccc2)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110118116A1,C#CCC(N)c1cccc(C)c1C.S=C=NCCCl>>C#CCC(NC1=NCCS1)c1cccc(C)c1C,,CCOCC,,[Na+].[OH-],,test
US20070281963A1,COC(=O)c1cc(OC)c(OC(C)C)cc1NCc1ccc(OC)cc1>>COc1ccc(CNc2cc(OC(C)C)c(OC)cc2C(=O)O)cc1,,C1CCOC1,,CO,[Na+].[OH-],test
US20050090524A1,CS(=O)(=O)Cl.Cc1ccc2nc(N3CC[C@@H](O)C3)ccc2c1NC(=O)CC12CC3CC(CC(C3)C1)C2>>Cc1ccc2nc(N3CC[C@@H](OS(C)(=O)=O)C3)ccc2c1NC(=O)CC12CC3CC(CC(C3)C1)C2,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20140046069A1,O=C1c2ccccc2C(=O)N1Cc1cnc(N2CCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)nc1C(F)(F)F>>NCc1cnc(N2CCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)nc1C(F)(F)F,,CCO,,NN,O,test
US20110136780A1,CC1(NCc2c[nH]c3nccc(C(=O)O)c23)CCN(C(=O)OC(C)(C)C)CC1>>CC1(N2Cc3c[nH]c4nccc(c34)C2=O)CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04902794,CCC(=O)OC(=O)CC.OCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2>>CCC(=O)O.OCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2,,O,,,,test
US20110190339A1,C=C(C(=O)N(C)OC)C(F)(F)F.C=CC(=C)O[Si](C)(C)C>>CON(C)C(=O)C1(C(F)(F)F)CCC(=O)CC1,,C1CCOC1,,Cl,,test
US20130022587A1,CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@@H](n2cnc(C=O)c2)CC1>>O=Cc1cn([C@@H]2CC[C@@H](O)CC2)cn1,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20080181866A1,CC(=O)c1ccc([C@@H]2NC(C(=O)O)CS2)cc1.O=C(Cl)OCc1ccccc1>>CC(=O)c1ccc([C@H]2SCC(C(=O)O)N2C(=O)OCc2ccccc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20130116250A1,CCCn1c(C)nc2ccc(C(=O)c3nc(-c4cccc(C(=O)OC)c4)c4ccccn34)cc2c1=O>>CCCn1c(C)nc2ccc(C(=O)c3nc(-c4cccc(C(=O)O)c4)c4ccccn34)cc2c1=O,,C1CCOC1,,[Na+].[OH-],,test
US20080221148A1,CC(C)[Si](Cl)(C(C)C)C(C)C.Fc1cc(OCc2ccccc2)c(F)cc1Cc1c[nH]c2ncccc12>>CC(C)[Si](C(C)C)(C(C)C)n1cc(Cc2cc(F)c(OCc3ccccc3)cc2F)c2cccnc21,,C1CCOC1,,O,[H-].[Na+],test
US20120115846A1,CCN(CC)S(F)(F)F.COc1ccc(Cn2c(=O)c3cc(CO)ccc3n(C3CCOCC3)c2=O)cc1OC>>COc1ccc(Cn2c(=O)c3cc(CF)ccc3n(C3CCOCC3)c2=O)cc1OC,,ClCCl,,O=C([O-])O.[Na+],,test
US20120220564A1,CC(C)(C)OC(=O)N1CCC(N)CC1.O=C=Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)NC1CCNCC1,,ClCCl,,,,test
US06593326B1,CC(C)N.CC1(CCl)CO1.O=[N+]([O-])c1ccc(O)cc1>>CC(C)NCC(C)(O)COc1ccc([N+](=O)[O-])cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110144110A1,CCOC(=O)CCc1ccc(-c2ccc(OC)cc2)n1-c1nc(C(N)=O)cs1>>COc1ccc(-c2ccc(CCC(=O)O)n2-c2nc(C(N)=O)cs2)cc1,,C1CCOC1,CO,[Li+].[OH-],,test
US20110140044A1,C1CCC(P(C2CCCCC2)C2CCCCC2)CC1.C1COCCO1.O=S(=O)(c1cc(Cl)cc(Cl)c1)c1cc(Cl)cc(Cl)c1.OB(O)c1ccccc1>>O=S(=O)(c1cc(-c2ccccc2)cc(-c2ccccc2)c1)c1cc(-c2ccccc2)cc(-c2ccccc2)c1,,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US05972926,CC(C)(C)OC(=O)C(NCC(=O)OCc1ccccc1)C(=O)OCc1ccccc1>>O=C(O)CNCC(=O)O,,C1COCCO1,,CCOCC,Cl,test
US20090181942A1,CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2-n2c1nnc2C(F)(F)F>>COc1cccc([C@H]2O[C@H](CCO)c3nnc(C(F)(F)F)n3-c3ccc(Cl)cc32)c1OC,,C1CCOC1,,O,[BH4-].[Li+],test
US20130261138A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.C[C@H]1NC(=O)[C@@H](NC(=O)OC(C)(C)C)C[C@H]1c1ccccc1>>C[C@H]1NC(=S)[C@@H](NC(=O)OC(C)(C)C)C[C@H]1c1ccccc1,,Cc1ccccc1,,,,test
US04304770,CC(C)(C)OC(=O)CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nncs3)CS[C@H]12)c1csc(NC=O)n1>>CC(C)(C)OC(=O)CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nncs3)CS[C@H]12)c1csc(N)n1,,CO,,Cl,,test
US20090197859A1,C=O.CC(C)(C)OC(=O)c1cccc(C2CCNCC2)n1>>CN1CCC(c2cccc(C(=O)OC(C)(C)C)n2)CC1,,CO,,[BH3-]C#N.[Na+],,test
US20100216788A1,O=[N+]([O-])c1ccc(Oc2cccc(S(=O)(=O)CC3CC3)c2)c(Cl)c1>>Nc1ccc(Oc2cccc(S(=O)(=O)CC3CC3)c2)c(Cl)c1,,CCO,,[Ca+2].[Cl-].[Cl-],,test
US20060069077A1,CN1CCN(CC(N)=S)CC1.O=C(CCl)CCl>>CN1CCN(Cc2nc(CCl)cs2)CC1.Cl,,ClC(Cl)Cl,,O=S(Cl)Cl,O=C([O-])O.[Na+],test
US20070099990A1,Cc1c(C)c2c(c(C)c1NC(=O)OCC(Cl)(Cl)Cl)C(c1ccc(C(C)C)cc1)CO2.NCCCO>>Cc1c(C)c2c(c(C)c1NC(=O)NCCCO)C(c1ccc(C(C)C)cc1)CO2,,CCCCCC,CCOC(C)=O,,,test
US20020040146A1,C=C1C[C@@H](CO)N(C(=O)OC(C)(C)C)C1.Fc1cc(F)c(CBr)cc1F>>C=C1C[C@@H](COCc2cc(F)c(F)cc2F)N(C(=O)OC(C)(C)C)C1,,C1CCOC1,CCOC(C)=O,[H-].[Na+],[Cl-].[NH4+],test
US05348978,C[C@H](N[C@@H](CCc1ccccc1)C(=O)OCc1ccccc1)C(=O)O[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1>>C[C@H](N[C@@H](CCc1ccccc1)C(=O)O)C(=O)O[C@@H](Cc1ccccc1)C(=O)O,[Pd],CCOC(C)=O,,O=C(O)C(F)(F)F,,test
US20140024650A1,CCOC(=O)C1CN(Cc2ccccc2)CCC1=O.CON>>CCOC(=O)C1CN(Cc2ccccc2)CCC1=NOC,,CCOC(C)=O,c1ccncc1,Cl,Cl,test
US20060084644A1,FC(F)(F)Oc1ccc(Nc2cc(N3CCCCC3)cc(Cl)n2)cc1.OB(O)c1ccc(F)cc1>>Fc1ccc(-c2cc(N3CCCCC3)cc(Nc3ccc(OC(F)(F)F)cc3)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US04150235,CCCCCC(O)CCCC(CC=Cc1cccc(C(=O)O)c1)C(C)=O>>CCCCCC(O)CCCC(CCCc1cccc(C(=O)O)c1)C(C)=O,[Pd],CCO,,[H][H],,test
US20140038960A1,Fc1ccc(Cl)cc1-c1cc(Cl)c2cccnc2n1.OB(O)c1cncc(-c2ccccc2)c1>>Fc1ccc(Cl)cc1-c1cc(-c2cncc(-c3ccccc3)c2)c2cccnc2n1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US04415572,O=C(O)CC(=O)O.O=Cc1cc(N2CCNCC2)ccc1[N+](=O)[O-]>>O=C(O)C=Cc1cc(N2CCNCC2)ccc1[N+](=O)[O-],,c1ccncc1,,C1CCNCC1,Cl,test
US20040010032A1,CCCCc1oc2ccc([N+](=O)[O-])cc2c1C(=O)c1ccc(OCCCN(CCCC)CCCC)cc1>>CCCCc1oc2ccc([N+](=O)[O-])cc2c1C(=O)c1ccc(OCCCN(CCCC)CCCC)cc1,,O=C([O-])O,[Na+],Cl,O,test
US20090286778A1,CC(C)(C)OC(=O)CBr.O=[N+]([O-])c1ccc(O)c(I)c1>>CC(C)(C)OC(=O)COc1ccc([N+](=O)[O-])cc1I,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110144066A1,CCCCCCCCCCCCc1ccc(S(=O)(=O)Cl)cc1.Nc1nnc(CCCCCBr)s1>>CCCCCCCCCCCCc1ccc(S(=O)(=O)Nc2nnc(CCCCCBr)s2)cc1,,c1ccncc1,,Cl,,test
US04846882,CONC(C)=O.Fc1ccc(CBr)c(Cl)c1>>CON(Cc1ccc(F)cc1Cl)C(C)=O,C1COCCOCCOCCOCCOCCO1,C1CCOC1,CCOCC,[K+].[OH-],,test
US04384152,C1=CC2=CC=C3CCCCC3C2CC1>>c1ccc2c(c1)CCCC2,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20020032340A1,CC[Si](CC)(CC)OC(C)(C)CCCS[C@@H](C)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>C[C@H](SCCCC(C)(C)O)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090281075A1,Cc1cc(Br)ccc1OC(F)(F)F.O=C1CCC(=O)N1Br>>FC(F)(F)Oc1ccc(Br)cc1CBr,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20050182072A1,CC(Nc1cc(-c2cc3nccn3c(N3CC4CC3CN4)n2)ccn1)c1ccccc1.CCCC=O>>CCCCN1C[C@@H]2C[C@H]1CN2c1nc(-c2ccnc(N[C@@H](C)c3ccccc3)c2)cc2nccn12,,ClC(Cl)Cl,ClCCl,CO,,test
US20060199817A1,Cc1ccc(C(=O)O)cc1Br.NC1CC1>>Cc1ccc(C(=O)NC2CC2)cc1Br,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20140171403A1,CNCCC1CN(C(=O)OCc2cc(Cl)cc(Cl)c2)CCO1.O=C(O)c1c[nH]c(=O)o1>>CN(CCC1CN(C(=O)OCc2cc(Cl)cc(Cl)c2)CCO1)C(=O)c1c[nH]c(=O)o1,,CCOC(C)=O,CN(C)C=O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20050085541A1,COC(Cl)Cl.COc1ccc(Oc2c(C)cc([N+](=O)[O-])c3c2CCC3)cc1>>COc1ccc(Oc2c(C)cc([N+](=O)[O-])c3c2CCC3)cc1C=O,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20040152882A1,O=C1CCc2ccccc21>>C1=Cc2ccccc2C1,,CO,,C1CCOC1,[BH4-].[Na+],test
US20100048636A1,CC(C)(C)OC(=O)N1[C@@H](C[C@@H](CCC(=O)OC2CCCCC2)C(=O)N2C(=O)OC[C@H]2c2ccccc2)COC1(C)C>>CC(C)(C)OC(=O)N1[C@@H](C[C@H](CO)CCC(=O)OC2CCCCC2)COC1(C)C,,C1CCOC1,,CO,[BH4-].[Na+],test
US20090062317A1,CC(C)(C)OC(=O)N1CCN(CCC#N)CC1>>CC(C)(C)OC(=O)N1CCN(CCCN)CC1,[Ni],CO,N,,,test
US20040058918A1,O=C1NNC(c2ccncc2)C1c1ccc(Cl)cc1>>O=c1[nH][nH]c(-c2ccncc2)c1-c1ccc(Cl)cc1,[Pd],CCO,,,,test
US20050026916A1,CSC1=N[C@@H](c2ccccc2)[C@@H](c2ccccc2)N1C(=O)OC(C)(C)C.NCc1cccc(F)c1>>CC(C)(C)OC(=O)N1C(NCc2cccc(F)c2)=N[C@@H](c2ccccc2)[C@H]1c1ccccc1,,CO,,,,test
US20050159469A1,CC[C@H](C)[C@H](NC(=O)OC)C(=O)NN(Cc1ccc(-c2ccccn2)cc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C>>CC[C@H](C)[C@H](NC(=O)OC)C(=O)NN(Cc1ccc(-c2ccccn2)cc1)C[C@H](O)[C@@H](N)Cc1ccccc1,,C1CCOC1,,Cl,,test
US20160122364A1,Brc1cnc2c(N3CCOCC3)snc2c1.COC(=O)c1ccc(B(O)O)cc1OC>>COC(=O)c1ccc(-c2cnc3c(N4CCOCC4)snc3c2)cc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US04728645,CCOC(=O)Cc1ccc(C#N)cc1.O=C1CCC(=O)N1Br>>CCOC(=O)C(Br)c1ccc(C#N)cc1,,COCCOCCOC,,[H-].[Na+],,test
US05071999,CCOC(=O)N1CC2C(CCN2Cc2ccccc2)C1C>>CCOC(=O)N1CC2NCCC2C1C,[Pd],CCO,,,,test
US20160096834A1,CC(C)(C)OC(=O)NC(C)(C)c1nc(C(=O)O)no1.Cn1cc(-c2nc3c(-c4ccc(CN)c(F)c4)ccnc3[nH]2)cn1>>Cn1cc(-c2nc3c(-c4ccc(CNC(=O)c5noc(C(C)(C)NC(=O)OC(C)(C)C)n5)c(F)c4)ccnc3[nH]2)cn1,,CN(C)C=O,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US05952363,CC(=O)C1[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)CN1Cc1ccccc1>>CC(O)C1[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)CN1Cc1ccccc1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US05102892,COc1cccc2c(NCc3ccccc3C)cc(CO)nc12.Cl.O=S(Cl)Cl>>COc1cccc2c(NCc3ccccc3C)cc(CCl)nc12.Cl,CN(C)C=O,,,[Na+].[OH-],,test
US20040053963A1,COS(=O)(=O)OC.Oc1cc(O)c2ccccc2n1>>COc1cc(O)nc2ccccc12,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030225060A1,CC(=O)N[C@@H](C)c1cc(Cl)ccc1C1CCN(C(=O)OC(C)(C)C)CC1.Cl>>CC(=O)N[C@@H](C)c1cc(Cl)ccc1C1CCNCC1.Cl,,CCOC(C)=O,ClCCl,,,test
US20160145236A1,CCN(CC)S(F)(F)F.N#Cc1cccc(CO)c1>>N#Cc1cccc(CF)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20040034050A1,CCOC(=O)CBr.Oc1ccc2c(c1)OCO2>>O=C(O)COc1ccc2c(c1)OCO2,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110311474A1,CCOC(=O)C[C@H]1C[C@@H](CC)[C@@H](c2nnc3cnc4[nH]ccc4n23)C1.N/C(CO)=N\O>>CC[C@@H]1C[C@H](Cc2nc(CO)no2)C[C@@H]1c1nnc2cnc3[nH]ccc3n12,,CO,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],,test
US04728458,CCCCCCCCO.O=C(O)c1ccc(-c2ccc(O)cc2)cc1>>CCCCCCCCOC(=O)c1ccc(-c2ccc(O)cc2)cc1,,O,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US20010051657A1,Cc1cc([N+](=O)[O-])cc(C)c1Oc1ccc(O)c(C(C)C)c1>>Cc1cc(N)cc(C)c1Oc1ccc(O)c(C(C)C)c1,[Pd],CCO,CCOC(C)=O,,,test
US20110021522A1,CC1(C)OC(=O)CC(=O)O1.O=Cc1cc(OC(F)(F)F)ccc1O>>O=C(O)c1cc2cc(OC(F)(F)F)ccc2oc1=O,,O,,,,test
US20080009530A1,COC(=O)c1cc(OC(C)C)nn1Cc1ncc(C(F)(F)F)cc1Cl>>CC(C)Oc1cc(C(=O)O)n(Cc2ncc(C(F)(F)F)cc2Cl)n1,,CO,,C1CCOC1,[Na+].[OH-],test
US20040138286A1,CCOC(=O)C1CCC(Oc2ccc3[nH]ncc3c2)CC1>>O=C(O)C1CCC(Oc2ccc3[nH]ncc3c2)CC1,,C1CCOC1,CO,[Li+].[OH-],,test
US20050107449A1,COC(=O)CCc1ccc(SC(=O)N(C)C)cc1C>>COC(=O)CCc1ccc(S)cc1C,,CCOC(C)=O,CO,Cl,C[O-].[Na+],test
US04557865,C1NC2CC3CC1CC(C3)C2.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>O=C(c1ccc([N+](=O)[O-])cc1)N1CC2CC3CC(C2)CC1C3,,CCO,,,,test
US20120115862A1,COc1ccc2c(c1)C(=O)OC2.O=C1CCC(=O)N1Br>>COc1ccc(C=O)c(C(=O)O)c1,,Clc1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US06288061B1,O=C([O-])O.c1ccc(N2CCOCC2)cc1>>O=Cc1ccc(N2CCOCC2)cc1,,CN(C)C=O,,O=P(Cl)(Cl)Cl,,test
US20160122364A1,COc1ccc(B(O)O)cc1OC.OCCN(CCO)c1snc2cc(Br)cnc12>>COc1ccc(-c2cnc3c(N(CCO)CCO)snc3c2)cc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20090036492A1,CC#CCOc1cc(C)c(CNC(=O)c2c(OC)cc(O)c3c2OC2=CC(O)=C(C(C)=O)C(=O)[C@]23C)c(C)c1C.CON>>CC#CCOc1cc(C)c(CNC(=O)c2c(OC)cc(O)c3c2OC2=CC(O)=C(/C(C)=N/OC)C(=O)[C@]23C)c(C)c1C,,C1CCOC1,CO,Cl,O=C([O-])O.[Na+],test
US05112836,N#Cc1cc(C(=O)OCc2ccccc2)c2c(c1)C(C(=O)OCc1ccccc1)CCN2.O>>NC(=O)c1cc(C(=O)O)c2c(c1)C(C(=O)O)CCN2,,CCO,O,Cl,[Na+].[OH-],test
US20110166128A1,CCCCCCCCC(CCCCCCCC)C(=O)OCI.Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1>>CCCCCCCCC(CCCCCCCC)C(=O)OC[N+]1(C)CCN(C2=Nc3ccccc3Nc3sc(C)cc32)CC1.[I-],,CCOC(C)=O,,,,test
US20110166135A1,CC(=O)OC(C)=O.O=c1[nH]c(CO)nc2ccccc12>>CC(=O)OCc1nc2ccccc2c(=O)[nH]1,,c1ccncc1,,,,test
US20070129372A1,C=Cc1ccc(C(=O)N2CCCC2)cc1-c1c(=O)ccn2nc(Oc3ccc(F)cc3F)ccc12>>CCc1ccc(C(=O)N2CCCC2)cc1-c1c(=O)ccn2nc(Oc3ccc(F)cc3F)ccc12,,CCOC(C)=O,,,,test
US20160137652A1,CCOC(=O)C(C)Br.Fc1ccc2nccc(N3CCNCC3)c2c1>>CCOC(=O)C(C)N1CCN(c2ccnc3ccc(F)cc23)CC1,,CN1CCCC1=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20010021718A1,COC(=O)CNC(=O)c1nc([C@H](CCCC2CCCCC2)CC(=O)NOCc2ccccc2)oc1C>>Cc1oc([C@H](CCCC2CCCCC2)CC(=O)NOCc2ccccc2)nc1C(=O)NCC(=O)O,,C1COCCO1,O,[Na+].[OH-],,test
US20070004675A1,O=[N+]([O-])c1ccc(Oc2ccnc3cc(I)sc23)c(F)c1>>Nc1ccc(Oc2ccnc3cc(I)sc23)c(F)c1,[Fe],CCO,O,[Cl-].[NH4+],,test
US05244889,CCOC(=O)C1CCCCCCC(CC(=O)OC(C)(C)C)C(=O)N1>>CC(C)(C)OC(=O)CC1CCCCCCC(CO)NC1=O,,CC(C)(C)O,,CO,[BH4-].[Na+],test
US20120004233A1,CC(C)(C)OC(=O)C1C(=O)CCc2cn3ccccc3c21>>O=C1CCc2cn3ccccc3c2C1,,CCOC(C)=O,,O=CO,,test
US04973597,Cc1cccc(C)c1N.O=C(O)c1ccc(Cl)nc1>>Cc1cccc(C)c1NC(=O)c1ccc(Cl)nc1,,CC(C)=O,O,CCN(CC)CC,CCOC(=O)Cl,test
US20150057260A1,CCN(CC)CC.CNN.O=Cc1c(Cl)cc(Cl)nc1Cl>>Cn1ncc2c(Cl)cc(Cl)cc21,,CCN(CC)CC,,CCO,,test
US20050032786A1,N#C/C=C/c1ccccn1>>N#CCCc1ccccn1,,CC(C)O,,O,[BH4-].[Na+],test
US20110143149A1,COS(C)(=O)=O.CO[Si](CCc1ccccn1)(OC)OC>>CO[Si](CCc1cccc[n+]1C)(OC)OC.CS(=O)(=O)[O-],,CCOC(C)=O,,,,test
US20030171418A1,CCOC(C)OC1COc2ccc3cnn(CC(C)N=[N+]=[N-])c3c2C1>>CC(Cn1ncc2ccc3c(c21)CC(O)CO3)N=[N+]=[N-],,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20020013468A1,O=C([O-])C=Cc1cnc2ccccc2c1>>OCC=Cc1cnc2ccccc2c1,,ClCCl,,CC(C)C[Al+]CC(C)C.[H-],,test
US20060264474A1,Cn1nc(-c2cccc(C(C)(C)N)c2)cc1-c1ccc(F)cc1.O=S(=O)(Cl)NCC(F)(F)F>>Cn1nc(-c2cccc(C(C)(C)NS(=O)(=O)NCC(F)(F)F)c2)cc1-c1ccc(F)cc1,,ClCCl,,CCN(CC)CC,,test
US20070219186A1,CC(C)[Si](C(C)C)(C(C)C)n1ccc(-c2cnn3c(-c4cccc(NC(=O)c5cccc(C(F)(F)F)c5)c4)ccnc23)c1>>O=C(Nc1cccc(-c2ccnc3c(-c4cc[nH]c4)cnn23)c1)c1cccc(C(F)(F)F)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04933355,OCc1csc(NCc2ccccc2)n1>>O=Cc1csc(NCc2ccccc2)n1,,CCN(CC)CC,,,,test
US20040248854A1,COC(=O)COCCCCN1C(=O)CCC[C@@H]1/C=C/C(=O)Cc1ccccc1>>COC(=O)COCCCCN1C(=O)CCC[C@@H]1/C=C/C(O)Cc1ccccc1,,ClCCl,,CO,[BH4-].[Na+],test
US20160115125A1,CC(C)N.COC(=O)c1c(Cl)c(S(=O)(=O)Cl)cn1C>>COC(=O)c1c(Cl)c(S(=O)(=O)NC(C)C)cn1C,,CC#N,,O=C([O-])O.[Na+],,test
US04883822,C=CC(=O)CC.CC1C(=O)CCc2ccccc21>>CC1=C2CCc3ccccc3C2(C)CCC1=O,,CO,,Cl,[K+].[OH-],test
US06331553B1,COc1ccc(C(=O)O)c(Nc2cccc(CNC(=O)OC(C)(C)C)c2)n1>>COc1ccc(CO)c(Nc2cccc(CNC(=O)OC(C)(C)C)c2)n1,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US20140107139A1,O=[N+]([O-])c1ccc(Oc2ccc3c(c2)COC3)cc1>>Nc1ccc(Oc2ccc3c(c2)COC3)cc1,[Pd],CCO,,NN,O,test
US20080262020A1,CC(C)(C)C(=O)Cl.Cn1c(=O)c(-c2ccc(F)cc2)cc2c3cc(-c4csc(CO)n4)ccc3n(C)c21>>Cn1c(=O)c(-c2ccc(F)cc2)cc2c3cc(-c4csc(COC(=O)C(C)(C)C)n4)ccc3n(C)c21,,c1ccncc1,,O,,test
US20130018043A1,NCc1c(-c2ncco2)n(-c2ccccc2)c2cc(Cl)ccc2c1=O.O=C(O)c1ccn(Cc2ccccc2)c(=O)c1>>O=C(NCc1c(-c2ncco2)n(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccn(Cc2ccccc2)c(=O)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20060160864A1,CCCCOCCOc1ccc(-c2ccc(N(CC(C)C)CC(C)C)c(/C=C/C(=O)O)c2)cc1.CCCn1cncc1C[S@](=O)c1ccc(N)cc1>>CCCCOCCOc1ccc(-c2ccc(N(CC(C)C)CC(C)C)c(/C=C/C(=O)Nc3ccc([S@@](=O)Cc4cncn4CCC)cc3)c2)cc1,CN(C)C=O,C1CCOC1,O,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US06350761B1,N#Cc1cccc(C=CC=O)c1>>N#Cc1cccc(CC=CO)c1,,CO,,[BH4-].[Na+],,test
US20160186094A1,CCCCCCCCCCC(C)c1ccc(COCCO[Si](C)(C)C(C)(C)C)cc1>>CCCCCCCCCCC(C)c1ccc(COCCO)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04621084,CC(Br)C(=O)Br.Cn1c(=O)sc2ccccc21>>CC(Br)C(=O)c1ccc2sc(=O)n(C)c2c1,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20080255239A1,CON=C1CCc2c1cccc2[N+](=O)[O-]>>Nc1cccc2c1CCC2N,[Pd],O=C(O)C(F)(F)F,,,,test
US08703700B2,COC(=O)c1csc(-c2cccc(OCCCCCO)c2)n1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COC(=O)c1csc(-c2cccc(OCCCCCOC(=O)Cl)c2)n1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,,test
US20120309739A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4ncc(Cl)nc4c3-c3ccccc3)cc2)CCC1.OB(O)c1cncnc1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4ncc(-c5cncnc5)nc4c3-c3ccccc3)cc2)CCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20090042949A1,CCOC(=O)C=C(CC(=O)OCC)Nc1ccc(OC(C)C)cc1.O=C1C=CC(=O)C=C1>>CCOC(=O)Cc1c(C(=O)OCC)c2cc(O)ccc2n1-c1ccc(OC(C)C)cc1,,CC#N,,,,test
US06482824B1,CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1.COc1ccc(C2ONC(C)C=C2C)cc1>>COc1ccc(C2ON(S(=O)(=O)c3ccc(NC(C)=O)cc3)C(C)C=C2C)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20070032530A1,Cc1nc(-c2ccc(F)cc2)ccc1CO.O=S(Cl)Cl>>Cc1nc(-c2ccc(F)cc2)ccc1CCl,,CN(C)C=O,,,,test
US20030139418A1,COC(=O)c1ccc(OCc2ccccc2OCc2ccccc2)cc1>>O=C(O)c1ccc(OCc2ccccc2OCc2ccccc2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20070287737A1,N=C(n1ccnc1)n1ccnc1.NNC(=O)c1ccncc1Nc1ccc(I)cc1F>>Nc1nnc(-c2ccncc2Nc2ccc(I)cc2F)o1,,CS(C)=O,,,,test
US20060122221A1,Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(cnn2C2CCN(C(=O)OC(C)(C)C)CC2)c1.Cl>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(cnn2C2CCNCC2)c1.Cl,,C1COCCO1,,CO,,test
US06666989B1,CCCCCC[C@H](C)O.O=C(O)c1ccc(OCc2ccccc2)c(F)c1>>CCCCCC[C@@H](C)OC(=O)c1ccc(OCc2ccccc2)cc1F,,C1CCOC1,ClCCl,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US03966736,CCc1cc2c(cc1CC)-n1c(n[nH]c1=O)-c1cccnc1N2C(=O)CN1CCCC1.Cc1ccccc1C.ClCCCN1CCCC1>>O=c1ccc2ccccc2nn1,,Cc1ccccc1C,,CN(C)C=O,[H-].[Na+],test
US20110065691A1,CCOC(=O)CN1CCN(c2ccc(OC)c3nc(C(F)(F)F)ccc23)C[C@@H]1Cc1ccccc1.CN>>CNC(=O)CN1CCN(c2ccc(OC)c3nc(C(F)(F)F)ccc23)C[C@@H]1Cc1ccccc1,,CCO,,[C-]#N.[Na+],,test
US20040147580A1,BrBr.COC(=O)c1cccnc1N>>COC(=O)c1cc(Br)cnc1N,,CC(=O)O,,,,test
US05047411,CN=C=S.Nc1ccc(CCc2ccccn2)cc1>>CNC(=S)Nc1ccc(CCc2ccccn2)cc1,,CCO,,,,test
US20130158057A1,CI.CNc1nc(Nc2ccc(-c3nn[nH]n3)cc2Cl)ncc1C(F)(F)F>>CNc1nc(Nc2ccc(-c3nnn(C)n3)cc2Cl)ncc1C(F)(F)F,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090163508A1,Fc1cccc(F)c1-c1ccnc(N2CCNCC2)n1.O=C(Nc1cccnn1)OCC(Cl)(Cl)Cl>>O=C(Nc1cccnn1)N1CCN(c2nccc(-c3c(F)cccc3F)n2)CC1,,C1CCOC1,CCCCCC,Cl,Cl,test
US20060270609A1,CC(C)=CCCC(C)CCO.O=C(O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2>>CC(C)=CCCC(C)CCOC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US06239151B1,CC(C)C[C@@H](C(=O)NN(CC(C)C)C(=O)C[C@](N)(OC(C)(C)C)C(=O)O)[C@H](C/C=C/c1ccccc1)C(=O)NO.O=C(O)C(F)(F)F>>CC(C)C[C@@H](C(=O)NN(CC(C)C)C(=O)C[C@H](N)C(=O)O)[C@H](C/C=C/c1ccccc1)C(=O)NO.O=C(O)C(F)(F)F,,ClCCl,,Cl,,test
US20080085890A1,CC1CCCN1Cc1ccc(N)cc1.CO/C=C1/C(=O)NC(=O)c2ccc(I)cc21>>CC1CCCN1Cc1ccc(N/C=C2\C(=O)NC(=O)c3ccc(I)cc32)cc1,,CN(C)C=O,,,,test
US05332739,BrP(Br)Br.O=[N+]([O-])c1ccccc1CCO>>O=[N+]([O-])c1ccccc1CCBr,,c1ccccc1,,O,,test
US04436662,COC(=O)CBr.Cc1[nH]cc2c1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2>>COC(=O)Cn1cc2c(c1C)-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2,,CN(C)C=O,O,CC(C)(C)[O-].[K+],,test
US20090042892A1,N#Cc1cc2c(cc1N)CCC2.[I-]>>N#Cc1cc2c(cc1I)CCC2,,ClC(Cl)Cl,,CC(C)CCON=O,,test
US20110098297A1,COCC(COC)Oc1cc(Oc2ccc(S(C)(=O)=O)nc2)cc2cc(C(N)=O)[nH]c12.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COCC(COC)Oc1cc(Oc2ccc(S(C)(=O)=O)nc2)cc2cc(C(N)=S)[nH]c12,,C1CCOC1,,,,test
US05201931,CC(=O)OC/C=C(/C)C#CC12OC1(C)CC(O)CC2(C)C>>C/C(C#CC12OC1(C)CC(O)CC2(C)C)=C/CO,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20070213331A1,CCCI.COC(=O)c1cc(O)cc(C(=O)OC)c1>>CCCOc1cc(C(=O)O)cc(C(=O)OC)c1,,CN(C)C=O,CO,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20090318408A1,CN.COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(CCCc1ccccc1)CC(F)(F)C(=O)N2C>>CNC(=O)c1ccc(Nc2ncc3c(n2)N(CCCc2ccccc2)CC(F)(F)C(=O)N3C)c(OC)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20130303509A1,CC(C)(C)OC(=O)NC1CNC1.Clc1ccc(Cl)nn1>>CC(C)(C)OC(=O)NC1CN(c2ccc(Cl)nn2)C1,,CS(C)=O,O,CCN(C(C)C)C(C)C,,test
US20120094972A1,Cc1c(Cl)nc2ncccc2c1Cl.OB(O)c1ccccc1>>Cc1c(-c2ccccc2)nc2ncccc2c1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US20110053940A1,CC(C)(C)OC(=O)N(Cc1cc(CO)cc(Cl)c1Cl)C1CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N(Cc1cc(COS(C)(=O)=O)cc(Cl)c1Cl)C1CC1,,CCOCC,ClCCl,CCN(C(C)C)C(C)C,,test
US20070004758A1,CCCSc1nccc(C(OC)OC)n1.CO>>COc1nccc(C(OC)OC)n1,,CO,,C[O-].[Na+],,test
US08207345B2,CCOC(=O)Cc1cc2cc(C)ccc2nc1-c1ccccc1>>Cc1ccc2nc(-c3ccccc3)c(CCO)cc2c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05352701,COc1ccc(/C=C/CCCCOc2ccc(C(=O)c3cccc(C(=O)O)c3)cc2OCC(=O)O)cc1>>COc1ccc(/C=C/CCCCOc2ccc(C(O)c3cccc(C(=O)O)c3)cc2OCC(=O)O)cc1,,C1COCCO1,O,[BH4-].[Na+],,test
US20060094754A1,CC(=O)CC(=O)C(F)(F)F.COc1ccc(C(=O)c2cc(OC(F)(F)F)ccc2N)cc1>>COc1ccc(-c2c(C(=O)C(F)(F)F)c(C)nc3ccc(OC(F)(F)F)cc23)cc1,,CCCCCCC,CCOC(C)=O,CC(C)O,,test
US20100256188A1,Nc1cc(CNC(=O)C2(C(F)(F)F)CC2)ccc1Cl.S=C(n1ccnc1)n1ccnc1>>O=C(NCc1ccc(Cl)c(N=C=S)c1)C1(C(F)(F)F)CC1,,ClCCl,,,,test
US03962247,CCOC(=O)Cl.COc1ccc(C(C#N)N2CCNCC2)c(OC)c1OC>>CCOC(=O)N1CCN(C(C#N)c2ccc(OC)c(OC)c2OC)CC1,,CCOCC,,c1ccncc1,,test
US20130237535A1,O=C(Cl)CCl.O=S(=O)(c1ccc(Br)cc1)N1CCC(O)(CNC2CC2)C(F)C1>>O=C(CCl)N(CC1(O)CCN(S(=O)(=O)c2ccc(Br)cc2)CC1F)C1CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20030092677A1,CC(C)(C)OC(=O)Nc1ccc(-c2cccc3ccccc23)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1ccc(-c2cccc3ccccc23)cc1N,[Ni],,,,,test
US20080207654A1,CCCCc1nc(C)n(C)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nc(C)n(C)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US04584308,CC(C)(Cc1ccc(Cl)cc1)C1(c2ccc(Cl)cc2)CO1.c1c[nH]cn1>>CC(C)(Cc1ccc(Cl)cc1)C(O)(Cn1ccnc1)c1ccc(Cl)cc1,,CCCO,,O,[Na],test
US20140288123A1,C1CCOC1.CC(CO)c1ccc(C(=O)[O-])cc1.Oc1ccccc1>>COC(=O)c1ccc(C(C)COc2ccccc2)cc1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06117888,CCOC(=O)Cn1c(C)cc(SCCO)c([N+](=O)[O-])c1=O.ClP(Cl)(Cl)(Cl)Cl>>CCOC(=O)Cn1c(C)cc(SCCCl)c([N+](=O)[O-])c1=O,,ClCCl,,,,test
US20140309244A1,C/C(=N\OCC(C)Cc1cccc(C(C)O)n1)c1cccc(C)n1>>CC(=O)c1cccc(CC(C)CO/N=C(\C)c2cccc(C)n2)n1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20100093818A1,CCOC(=O)c1ccc(N)cc1.CO[C@@H](c1ccccc1)c1nc2cc(F)c(F)cc2n1C(C(=O)O)C1CCCCC1>>CCOC(=O)c1ccc(NC(=O)C(C2CCCCC2)n2c([C@@H](OC)c3ccccc3)nc3cc(F)c(F)cc32)cc1,,ClCCl,,O=S(Cl)Cl,c1ccncc1,test
US20160039821A1,CCNC(=O)c1cc2c(-c3cc(CS(C)(=O)=O)ccc3Nc3ccc(F)cc3F)cn(C)c(=O)c2[nH]1.CCOC(=O)C=O>>CCNC(=O)c1[nH]c2c(=O)n(C)cc3c2c1C(C(=O)OCC)N(c1ccc(F)cc1F)c1ccc(CS(C)(=O)=O)cc1-3,Cl[Ti](Cl)(Cl)Cl,C1CCOC1,,,,test
US04288592,CC(=O)Cl.Nc1cc(Cl)c(Cl)cc1Cl>>CC(=O)Nc1cc(Cl)c(Cl)cc1Cl,,ClCCl,,,,test
US20060281772A1,COc1cc2ncnc(C3CCNCC3)c2cc1OC.O=C(Nc1ccc(OC2CCC2)nc1)Oc1ccc([N+](=O)[O-])cc1>>COc1cc2ncnc(C3CCN(C(=O)Nc4ccc(OC5CCC5)nc4)CC3)c2cc1OC,,CC(C)=O,,ClCCl,,test
US20090247534A1,COC(=O)CC1CCC(c2ccc(-c3ccc(Br)cn3)cc2)CC1.FC(F)(F)c1ccc(Nc2cnc(Br)cn2)cn1>>COC(=O)CC1CCC(c2ccc(-c3cnc(Nc4ccc(C(F)(F)F)nc4)cn3)cc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US05998438,CCCC[Sn](CCCC)(CCCC)C1=CCCCC1.CN(C)CCc1cn(C(=O)c2ccccc2)c2ccc(Br)cc12>>CN(C)CCc1cn(C(=O)c2ccccc2)c2ccc(C3=CCCCC3)cc12,,Cc1ccccc1,,,,test
US04022768,C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)C=C[C@]4(C)[C@H]3CC[C@@]21C.O=C1N=NC(=O)N1c1ccccc1>>C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@@]21C,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150157736A1,COCCN(CCC(=O)OCc1ccccc1)C(=O)CN(CCOC)C(=O)CN(CCOC)C(=O)CNC(=O)OCc1ccccc1>>COCCN(CCC(=O)O)C(=O)CN(CCOC)C(=O)CN(CCOC)C(=O)CN,[Pd],CCOC(C)=O,,,,test
US20050090524A1,CC(C)(C)OC(=O)N(CCN)CCO.O=Cc1ccc2c(NC(=O)CC34CC5CC(CC(C5)C3)C4)c(Cl)ccc2n1>>O=C(CC12CC3CC(CC(C3)C1)C2)Nc1c(Cl)ccc2nc(CNCCNCCO)ccc12,,CC(=O)O,CO,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070027071A1,Fc1ccc(Br)c(CBr)c1CBr.NCc1ccccc1>>Fc1ccc(Br)c2c1CN(Cc1ccccc1)C2,,CC#N,,O=C([O-])O.[K+],,test
US05610144,CC(C)(C)OC(=O)[C@@H]1CS[C@H](c2ccccc2)N1C(=O)CN.Cc1cccc(N=C=O)c1>>Cc1cccc(NC(=O)NCC(=O)N2[C@H](C(=O)OC(C)(C)C)CS[C@@H]2c2ccccc2)c1,,C1CCOC1,CCOC(C)=O,,,test
US04395550,CC1=CC2C(CC1)C(=O)NC(=O)N2C(C)C.Fc1ccc([Mg]Br)cc1>>CC1=CC2C(CC1)C(c1ccc(F)cc1)=NC(=O)N2C(C)C,,C1CCOC1,,Cl,[H-].[Na+],test
US20070112039A1,COc1ccc(N)c(C(=O)Nc2ccc(Cl)cn2)c1.N#Cc1ccc(C(=O)Cl)cc1>>COc1ccc(NC(=O)c2ccc(C#N)cc2)c(C(=O)Nc2ccc(Cl)cn2)c1.Cl,,C1CCOC1,,c1ccncc1,,test
US20080293164A1,COC(=O)Cl.O=C1C=CC(=O)N1>>COC(=O)N1C(=O)C=CC1=O,,CCOC(C)=O,,CN1CCOCC1,,test
US20100256357A1,C[C@H]1CNC[C@@H](C)O1.NS(=O)(=O)c1ccc(-c2nc(C=O)cn2Cc2ccccc2F)cc1>>C[C@H]1CN(Cc2cn(Cc3ccccc3F)c(-c3ccc(S(N)(=O)=O)cc3)n2)C[C@@H](C)O1,,CC#N,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04472433,BrP(Br)Br.O=[N+]([O-])c1c(CO)cccc1Oc1ccccc1Cl>>O=[N+]([O-])c1c(CBr)cccc1Oc1ccccc1Cl,,ClCCl,,O,,test
US20090036419A1,C[C@@H](NC(=O)OC(C)(C)C)c1cc(C(=O)O)no1.Nc1ccc(C(F)(F)F)cc1N>>C[C@@H](NC(=O)OC(C)(C)C)c1cc(-c2nc3ccc(C(F)(F)F)cc3[nH]2)no1,,C1CCOC1,O,CC(C)COC(=O)Cl,CCN(CC)CC,test
US20160052897A1,Fc1cc(Br)cc(C(F)(F)F)c1.O[C@H]1CCNC1>>O[C@H]1CCN(c2cc(Br)cc(C(F)(F)F)c2)C1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],O=C([O-])O.[Na+],test
US20090093472A1,Cc1noc([C@H]2CCCN2C(=O)OCc2ccccc2)c1Cc1ccc(Cl)cc1>>Cc1noc([C@H]2CCCN2)c1Cc1ccc(Cl)cc1,,ClCCl,,C[Si](C)(C)I,,test
US20080004309A1,CC(=O)OC(C)=O.CCOC(=O)c1nc(C#N)c2c(ccn2Cc2ccc(F)cc2)c1O>>CCOC(=O)c1nc(C#N)c2c(ccn2Cc2ccc(F)cc2)c1OC(C)=O,,CCN(CC)CC,,,,test
US08466154B2,CN1CCNCC1.Cl.O=C(O)c1ccc(CCl)cc1>>CN1CCN(Cc2ccc(C(=O)O)cc2)CC1.Cl.Cl,[Pd],CCO,,,,test
US20150232454A1,CO.COCn1ncc(Cl)c(Cl)c1=O>>COCn1ncc(Cl)c(OC)c1=O,,CO,,C[O-].[Na+],,test
US20090137609A1,CC(C)(C)[Si](C)(C)Cl.CCOC(=O)c1ccc(O)c(OC)c1>>COC(=O)c1ccc(O[Si](C)(C)C(C)(C)C)c(OC)c1,,CN(C)C=O,,c1c[nH]cn1,,test
US20070112068A1,N#CCC#N.O=S(=O)(OCC(F)(F)C(F)C(F)(F)F)C(F)(F)F>>N#CC(C#N)CC(F)(F)C(F)C(F)(F)F,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080045528A1,CSc1nc2ccc(O)cc2s1.Clc1ccnc2ccccc12>>CSc1nc2ccc(Oc3ccnc4ccccc34)cc2s1,,CN1CCCC1=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US05138069,CCCCc1nc(Cl)c(CO)n1Cc1ccc(OCc2ccccc2)cc1>>CCCCc1ncc(CO)n1Cc1ccc(O)cc1,[Pd],CO,,,,test
US20060040999A1,COc1ccc(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CNCC(N)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CN1CC(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)NC1=O,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20070015784A1,C[Si](C)(C)Cl.O=C(c1cccc(F)c1F)N1CCC2(CC1)N[C@@H](Cc1ccccc1)C(=O)N2Cc1ccccc1>>Cl.O=C(c1cccc(F)c1F)N1CCC2(CC1)N[C@@H](Cc1ccccc1)C(=O)N2Cc1ccccc1,,CCC(C)=O,,CCOCC,O,test
US05639776,CC(C)(C)NN.CCOC(=O)C(C)(C)C(=O)c1ccc(Cl)cc1>>CC(C)(C)N1N=C(c2ccc(Cl)cc2)CC1=O,,CC(=O)O,,Cl,CC(=O)[O-].[Na+],test
US20080032995A1,Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CCl.O=c1c(I)coc2cc(O)ccc12>>Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1ccc2c(=O)c(I)coc2c1,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20070093521A1,CCOc1cc(C=O)cc(OCC)c1-n1ccnn1.OCc1nccc2nc(NC3CCNCC3)oc12>>CCOc1cc(CN2CCC(Nc3nc4ccnc(CO)c4o3)CC2)cc(OCC)c1-n1cncn1,,CC(=O)O,CCO,CCN(C(C)C)C(C)C,[BH3-]C#N.[Na+],test
US20100160302A1,N#C[C@@H]1CCCN1C(=O)CCl.NC12CC3CC1CC(N1CCCC1=O)(C3)C2>>N#C[C@@H]1CCCN1C(=O)CNC12CC3CC1CC(N1CCCC1=O)(C3)C2,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20100016396A1,C=CC[Mg]Cl.C=Cc1c(C=O)nn(C)c1Oc1cc(OCc2ccc(OC)cc2)c(Cl)cc1Cl>>C=CCC(O)c1nn(C)c(Oc2cc(OCc3ccc(OC)cc3)c(Cl)cc2Cl)c1C=C,,C1CCOC1,,[Cl-].[NH4+],,test
US05693639,C#Cc1ccc(S(=O)(=O)N2CCCC2)cc1.CC(=O)C(F)(F)F>>CC(O)(C#Cc1ccc(S(=O)(=O)N2CCCC2)cc1)C(F)(F)F,,C1CCOC1,,[Li]CCCC,,test
US20090212280A1,Cl.c1ccc2c(c1)nc1ncccn12>>Cl.c1ccc2c(c1)nc1n2CCCN1,[Pd],,,,,test
US20080096922A1,COC(=O)C1=C(O)CCC(C#N)(c2cccc(OC)c2)C1>>COc1cccc(C2(C#N)CCC(=O)CC2)c1,,CS(C)=O,,O,,test
US04025505,Cc1ccc([N+](=O)[O-])cc1N1C(=O)c2ccc(F)cc2C1=O>>Cc1ccc(N)cc1N1C(=O)c2ccc(F)cc2C1=O,[Ni],CCOC(C)=O,,[H][H],,test
US20040006141A1,CCOC(=O)C(Cc1ccc(OCCO)cc1)Oc1ccc(C(C)C)cc1.CS(=O)(=O)Cl>>CCOC(=O)C(Cc1ccc(OCCOS(C)(=O)=O)cc1)Oc1ccc(C(C)C)cc1,,CCN(CC)CC,,,,test
US20090030006A1,Brc1ccc(-n2cccn2)cc1.COB(OC)OC>>OB(O)c1ccc(-n2cccn2)cc1,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US20090182140A1,Clc1cc(Cl)n2nccc2n1.NCc1ccc(Cl)cc1Cl>>Clc1ccc(CNc2cc(Cl)nc3ccnn23)c(Cl)c1,,C1COCCO1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US04734415,O=C1CCC(c2ccc(NC(=S)NC(=O)c3ccccc3)cc2)=NN1>>NC(=S)Nc1ccc(C2=NNC(=O)CC2)cc1,,CCO,O,[Na+].[OH-],,test
US06329389B1,COC(=O)CCC(N)=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COC(=O)CCC(N)=S,,Cc1ccccc1,,,,test
US20060293379A1,C=CC#N.O=Cc1cc(Cl)ccc1O>>N#CC1=Cc2cc(Cl)ccc2OC1,,CCOCC,,C1CN2CCN1CC2,,test
US20100048564A1,CC(C)(C)OC(=O)NCc1cc(Cl)ccc1[N+](=O)[O-].COc1cc(O)cc(F)c1>>COc1cc(F)cc(Oc2ccc([N+](=O)[O-])c(CNC(=O)OC(C)(C)C)c2)c1,,CN(C)C=O,,[H-].[Na+],,test
US04937246,COc1cc(CN2CCN(C(=O)c3ccc4c(c3)C(=O)C3(CC3)O4)CC2)cc(OC)c1OC>>COc1cc(CN2CCN(C(=O)c3ccc4c(c3)C(O)C3(CC3)O4)CC2)cc(OC)c1OC,,CO,ClCCl,[BH4-].[Na+],,test
US20120289495A1,CC1CN(C(=O)OC(C)(C)C)CCN1.N#Cc1ccc(Cl)nc1>>CC1CN(C(=O)OC(C)(C)C)CCN1c1ccc(C#N)cn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070270587A1,O.O=C1Nc2cc(Cl)ccc2C1(Br)Br>>O=C1Nc2cc(Cl)ccc2C1=O,,O,,CO,,test
US20030187014A1,CNc1ccccc1.Cc1nn(-c2ccccn2)c2ncc(C(=O)O)c(O)c12.O=P(Cl)(Cl)Cl>>Cc1nn(-c2ccccn2)c2ncc(C(=O)N(C)c3ccccc3)c(Cl)c12,,C1CCOC1,,CCN(CC)CC,,test
US20110130445A1,O=C(c1ccccc1)C(F)(F)F.O=[N+]([O-])O>>O=C(c1cccc([N+](=O)[O-])c1)C(F)(F)F,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20100152183A1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.FC(F)CI>>CC(C)(C)OC(=O)N[C@@H]1CCN(CC(F)F)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20070111988A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.Oc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(Br)sc2c1>>CC(C)(C)[Si](Oc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(Br)sc2c1)(c1ccccc1)c1ccccc1,,CN(C)C=O,,c1c[nH]cn1,,test
US05663165,CCOC(=O)C(N)CC.O=Cc1ccccc1>>CCOC(=O)C(CC)N=Cc1ccccc1,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US20110046162A1,N#CCC(N)=S.Nc1cc[nH]c(=O)c1.O=Cc1ccc(OCCO)cc1>>N#Cc1c(S)nc2cc[nH]c(=O)c2c1-c1ccc(OCCO)cc1,,CC(C)O,,CC(=O)O,,test
US20050080101A1,COC(=O)c1cccc(Nc2nccc(-c3cn[nH]c3-c3ccc(F)cc3)n2)c1>>OCc1cccc(Nc2nccc(-c3cn[nH]c3-c3ccc(F)cc3)n2)c1,,C1CCOC1,Cc1ccccc1,[Cl-].[NH4+],,test
US20090137561A1,CC1(C)OC(=O)CC(=O)O1.O=C1CCCCC1>>CC1(C)OC(=O)C(=C2CCCCC2)C(=O)O1,Cl[Ti](Cl)(Cl)Cl,C1CCOC1,,c1ccncc1,,test
US20080064695A1,CCOC(=O)CC(C)=O.O=C(CBr)c1ccc(Br)cc1>>CCOC(=O)C(CC(=O)c1ccc(Br)cc1)C(C)=O,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06548516B1,Fc1ccc(CC2CCNCC2)cc1.O=c1[nH]c2ccc(CCCCl)cc2o1>>O=c1[nH]c2ccc(CCCN3CCC(Cc4ccc(F)cc4)CC3)cc2o1,,CCO,,CCN(CC)CC,Cl,test
US20140155415A1,CC(C)[Si](OC1COc2ccc(S(=O)(=O)NC(c3ccccc3)c3cc4ccccc4o3)cc2OC1)(C(C)C)C(C)C>>O=S(=O)(NC(c1ccccc1)c1cc2ccccc2o1)c1ccc2c(c1)OCC(O)CO2,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20060281772A1,COC(=O)C1(c2ncnc3cc(OC)c(OC)cc23)CCN(C(=O)OC(C)(C)C)CC1>>COc1cc2ncnc(C3CCNCC3)c2cc1OC,,Cl,O,CO,[K+].[OH-],test
US20120245136A1,COc1cc(C(=O)N2CCC3(CC2)CC(CO)c2ccccc2O3)ccc1OC(C)C.CS(=O)(=O)Cl>>COc1cc(C(=O)N2CCC3(CC2)CC(COS(C)(=O)=O)c2ccccc2O3)ccc1OC(C)C,,ClCCl,,O,,test
US20110269712A1,CCOC(=O)Cn1nc(CC)cc1CC>>CCc1cc(CC)n(CC(=O)O)n1,,C1CCOC1,O,[Na+].[OH-],,test
US04243805,CC(=O)N1CCN(C2Cc3ccc(F)cc3Sc3ccc(C(C)C)cc32)CC1>>CCN1CCN(C2Cc3ccc(F)cc3Sc3ccc(C(C)C)cc32)CC1,,ClC(Cl)Cl,,CC(=O)Cl,,test
US05716624,COC(=O)c1ccc(C#CC(O)c2ccc3c(c2)C(C)(C)CCS3)cc1O>>COC(=O)c1ccc(C#CC(=O)c2ccc3c(c2)C(C)(C)CCS3)cc1O,,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20070093526A1,CNOC.O=C(O)c1nccc2ccccc12>>CON(C)C(=O)c1nccc2ccccc12,,ClCCl,,Cl,O=C(n1ccnc1)n1ccnc1,test
US20060089354A1,CC(C)(C)c1ccc(Nc2ncnc3cc(-c4ncccc4C(F)(F)F)ccc23)cc1OCCO.O=P([O-])(OCc1ccccc1)OCc1ccccc1>>CC(C)(C)c1ccc(Nc2ncnc3cc(-c4ncccc4C(F)(F)F)ccc23)cc1OCCOP(=O)(OCc1ccccc1)OCc1ccccc1,O=[Ag],CC#N,ClCCl,CCN(CC)CC,CS(=O)(=O)Cl,test
US20160137648A1,Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccc(F)cc1OC1CCN(C2COC(C)(C)OC2)CC1)C3>>Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccc(F)cc1OC1CCN(C(CO)CO)CC1)C3,,Cl,,C1COCCO1,,test
US20050020659A1,COC(=O)c1ccccc1CSc1cccc2cccnc12>>O=C(O)c1ccccc1,,CO,O,[Li+].[OH-],,test
US20120214762A1,CC(=O)c1cc(F)c(Br)cc1F.NN>>C/C(=N\N)c1cc(F)c(Br)cc1F,,CCO,,O,,test
US20080009482A1,CCNC(=O)CCNC1CCCC1.Clc1ncc(Br)c(Cl)n1>>CCNC(=O)CCN(c1nc(Cl)ncc1Br)C1CCCC1,,CC#N,,CCN(CC)CC,,test
US20080113966A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)Cn2c(CO)cnc21.CI>>COCc1cnc2n1C[C@H](c1cccc(F)c1F)CC[C@H]2NC(=O)OC(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US06107329,COC(=O)[C@H](Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1>>O=C(NC(Cc1ccccc1)C(=O)O)c1cc2cc(Cl)ccc2[nH]1,,C1CCOC1,,[Li+].[OH-],,test
US05880130,CCOC(=O)COc1ccc(Nc2cc(Nc3cccc(C)c3)ncn2)cc1.OCCNCCO>>Cc1cccc(Nc2cc(Nc3ccc(OCC(=O)N(CCO)CCO)cc3)ncn2)c1,,CCO,,,,test
US20070173498A1,CN(C)CC1CCc2cc(OCc3ccc(N)cc3)ccc2C1.COc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc(S(=O)(=O)Nc2ccc(COc3ccc4c(c3)CCC(CN(C)C)C4)cc2)cc1,,CCOC(C)=O,c1ccncc1,C1CCOC1,O=C([O-])[O-].[K+].[K+],test
US04277498,CC(C)CCCC(C)(C)O.N#CCN1C(=O)c2ccccc2C1=O>>CC(C)CCCC(C)(C)NC(=O)CN1C(=O)c2ccccc2C1=O,,CC(=O)O,,O,O=S(=O)(O)O,test
US20100226881A1,CO.O=C(O)c1ccn2nccc2c1>>COC(=O)c1ccn2nccc2c1,Cl,,,,,test
US05889178,CCNC(=O)[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(N[C@@H]4CC[C@@H](N)CC4)nc32)[C@H](O)[C@@H]1O.Cl>>CCNC(=O)[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(N[C@@H]4CC[C@@H](N)CC4)nc32)[C@H](O)[C@@H]1O.Cl,,CCO,,CCOCC,,test
US20160244414A1,COC(C)(OC)N(C)C.NC(=O)c1nn(-c2ccccc2)c(=O)cc1Oc1ccccc1>>CC(=NC(=O)c1nn(-c2ccccc2)c(=O)cc1Oc1ccccc1)N(C)C,,CCOCC,,Cc1ccccc1,,test
US04898874,N#CCc1cccc2c(-c3ccccc3)onc12.O>>NC(=O)Cc1cccc2c(-c3ccccc3)onc12,,CC(C)(C)O,,[K+].[OH-],,test
US20060154912A1,BrC(Br)(Br)Br.OCCOc1ccc(OCc2ccc(-c3ccccc3)cc2)cc1>>BrCCOc1ccc(OCc2ccc(-c3ccccc3)cc2)cc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04465502,CC(=O)c1cccc(C)c1NC(=O)CCl.CC(O)CO>>Cc1cccc(C2(C)OCC(C)O2)c1NC(=O)CCl,,Cc1ccccc1,,Cc1ccccc1S(=O)(=O)O,,test
US03953402,CC(C)(C)c1cc(O)cc(C(C)(C)C)c1O.O=C1C=CC(=O)O1>>CC(C)(C)c1cc(OC(=O)/C=C\C(=O)O)cc(C(C)(C)C)c1O,,O,,O=C(O)C(F)(F)F,,test
US20060293352A1,CS(=O)(=O)c1ccc(F)cc1.O.O=C1COc2ccc(Cl)cc2N1>>CS(=O)(=O)c1ccc(Nc2cc(Cl)ccc2OCC(=O)O)cc1,,CN1CCCC1=O,O,O=C([O-])[O-].[K+].[K+],,test
US20120071478A1,CNc1cnc2cc(Br)ccc2n1.Fc1ccc(CBr)cc1C(F)(F)F>>CN(Cc1ccc(F)c(C(F)(F)F)c1)c1cnc2cc(Br)ccc2n1,,CN(C)C=O,,O,[H-].[Na+],test
US04588719,COc1cccc2c1CCCC2(O)CN1CCCCC1>>COc1cccc2c1C=CCC2CN1CCCCC1,,O=S(=O)(O)O,,,,test
US20090227541A1,CCO.NC(=O)CCCOc1cccc2c1B(O)OC2C[N+](=O)[O-]>>CC(=O)O.NCC1OB(O)c2c(OCCCC(N)=O)cccc21,[Ni],,,N,,test
US04766133,Cc1ccnc(C)c1C.O=C(OO)c1cccc(Cl)c1>>Cc1cc[n+]([O-])c(C)c1C,,ClCCl,,,,test
US20090275566A1,CC(=O)Cl.CC1(c2cccc(Br)c2)CCSC(N)=N1>>CC(=O)NC1=NC(C)(c2cccc(Br)c2)CCS1,,ClCCl,,CCN(CC)CC,,test
US20110237584A1,CCOC(=O)CC(C)c1cccnc1>>CC(CCO)c1cccnc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06358971B1,O=C(c1ccc(F)cc1)c1ccc2nc(NC(=O)C(F)(F)F)c(-c3ccc(C(F)(F)F)cc3F)n2c1>>Nc1nc2ccc(C(=O)c3ccc(F)cc3)cn2c1-c1ccc(C(F)(F)F)cc1F,,CCOC(C)=O,,,,test
US20040044008A1,Brc1ccc(C2=CCNCC2)cc1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC=C(c2ccc(Br)cc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20090062360A1,CCOC(=O)CBr.O=C1NC2(CCCCC2)N=C1c1ccc(OC(F)(F)F)cc1>>CCOC(=O)CN1C(=O)C(c2ccc(OC(F)(F)F)cc2)=NC12CCCCC2,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04737516,Cc1cccc2c(CO)csc12.O=S(Cl)Cl>>Cc1cccc2c(CCl)csc12,,CCOCC,,,,test
US20020137937A1,O=C(O)/C=C/c1ccncc1>>O=C(O)CCC1CCNCC1,[Rh],O,,N,,test
US20090291959A1,COC(=O)CC(C(=O)OC)C(C)C=O.NN>>COC(=O)CC1C(=O)NN=CC1C,,CCO,,CC(=O)O,O,test
US20050032650A1,CC(C)C(=O)CCC(=O)O.NN>>CC(C)C1=NNC(=O)CC1,,CCO,,,,test
US06015825,CCc1cc(Cl)ncn1.c1nc[nH]n1>>CCc1cc(-n2cncn2)ncn1,,CO,ClCCl,,,test
US20120010191A1,CC#N.CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cccc1N1CCc2c(sc3c2CCCC3)C1=O.Cn1cc(Br)cc(Nc2cc3n(n2)CCOC3)c1=O>>CCn1cc(-c2cccc(N3CCc4c(sc5c4CCCC5)C3=O)c2COC(C)=O)cc(Nc2cc3n(n2)CCOC3)c1=O,Cl[Pd]Cl,CC#N,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],CC(=O)[O-].[Na+],test
US20040132727A1,CC(C)N(CCN)C(C)C.COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1N.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NCCN(C(C)C)C(C)C,,ClC(Cl)Cl,O,CCN(CC)CC,,test
US06573389B1,CC(=O)c1c(C)sc(C)c1Br>>Cc1sc(C)c([C@@H](C)O)c1Br,,C1CCOC1,,,,test
US20120083502A1,O=C1CCC(=O)N1Br.O=c1cc(CCl)nc2ccc(F)cn12>>O=c1c(Br)c(CCl)nc2ccc(F)cn12,,O,,CC(=O)O,,test
US20060074111A1,CCCS(=O)(=O)N(Cc1ccc(OCC(=O)OCC)c(C)c1)c1cccc(-c2ccc(C(F)(F)F)cc2)c1>>CCCS(=O)(=O)N(Cc1ccc(OCC(=O)O)c(C)c1)c1cccc(-c2ccc(C(F)(F)F)cc2)c1,,C1CCOC1,CO,[Na+].[OH-],,test
US20100069431A1,COC(=O)c1cc(O)cc(OC(C)C)c1.OCCCc1cccnc1>>COC(=O)c1cc(OCCCc2cccnc2)cc(OC(C)C)c1,,C1CCOC1,CCCCCC,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20040261190A1,CCOc1ccccc1OCC.COC(=O)CCC(=O)Cl>>CCOc1ccc(C(=O)CCC(=O)OC)cc1OCC,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20060142337A1,CC(=O)CBr.C[C@@H](O[C@H]1CCN(C(=O)C2CCNCC2)C[C@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.Cl>>CC(=O)CN1CCC(C(=O)N2CC[C@H](O[C@H](C)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](c3ccccc3)C2)CC1.Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20110034469A1,CC(C)(C)OC(=O)N1C[C@H]2CCCN2C[C@H]1c1nc(C(=O)c2cccc3ccccc23)cs1>>O=C(c1csc([C@@H]2CN3CCC[C@@H]3CN2)n1)c1cccc2ccccc12,,CCOC(C)=O,,Cl,,test
US20110034464A1,COCCS(=O)(=O)c1ccccc1CNC(=O)OC(C)(C)C.Cl>>COCCS(=O)(=O)c1ccccc1CN.Cl,,CCOC(C)=O,,C1COCCO1,,test
US06511974B1,Cc1cn(-c2ccc(C(=O)O)cc2)cn1.O=C(Cl)C(=O)Cl>>Cc1cn(-c2ccc(C(=O)Cl)cc2)cn1,CN(C)C=O,ClCCl,,,,test
US20090099155A1,NCc1ccc(OCC(F)(F)F)cn1.O=C(N1CCc2ccc(Cl)c(OS(=O)(=O)C(F)(F)F)c2CC1)C(F)(F)F>>O=C(N1CCc2ccc(Cl)c(NCc3ccc(OCC(F)(F)F)cn3)c2CC1)C(F)(F)F,,Cc1ccccc1,,,,test
US05284863,FC(F)(F)Sc1cc(C(F)(F)F)[nH]c1-c1ccc(Cl)cc1.OO>>O=S(=O)(c1cc(C(F)(F)F)[nH]c1-c1ccc(Cl)cc1)C(F)(F)F,,CC(=O)O,,CCOC(C)=O,O,test
US20090275538A1,O=C1COC(=S)N1.O=Cc1ccccc1O>>O=C1NC(=S)O/C1=C\c1ccccc1O,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US05382675,C1COCCO1.O.OC1CCOCC1>>C[C@@H](O)C(=O)OC1CCOCC1,,C1COCCO1,,[H-].[Na+],,test
US04444770,Cc1nn2c(C=O)c(-c3ccccc3)nc2s1.O=C(O)CC(=O)O>>Cc1nn2c(C=CC(=O)O)c(-c3ccccc3)nc2s1,,c1ccncc1,,C1CCNCC1,,test
US20160002273A1,Cc1nc(O)c2sccc2n1.O=P(Cl)(Cl)Cl>>Cc1nc(Cl)c2sccc2n1,,CN(C)C=O,ClCCCl,,,test
US20030232790A1,O=C(O)Cc1cncn1Cc1ccccc1>>OCCc1cncn1Cc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100160303A1,COCCBr.Cc1ccc2c(c1)C(=O)N(c1cccc(-c3ccc(C(N)=O)c4[nH]c5cc(O)ccc5c34)c1C)C2>>COCCOc1ccc2c(c1)[nH]c1c(C(N)=O)ccc(-c3cccc(N4Cc5ccc(C)cc5C4=O)c3C)c12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100190754A1,CCCCCI.O=c1[nH]c2ccccc2c(=O)o1>>CCCCCn1c(=O)oc(=O)c2ccccc21,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20140256705A1,CCS(=O)(=O)c1ccc(F)c(Br)c1.NCC1CC1>>CCS(=O)(=O)c1ccc(NCC2CC2)c(Br)c1,,C1COCCO1,,,,test
US05506256,CC(C)(C)OC(=O)N1CCC[C@H]1C1CO1.O=[N+]([O-])c1ccc(S)cc1>>CC(C)(C)OC(=O)N1CCC[C@H]1C(O)CSc1ccc([N+](=O)[O-])cc1,,CO,,CCN(CC)CC,,test
US20110046169A1,CCOC(=O)c1cc(C)cn(-c2ccc(F)cc2)c1=O>>Cc1cc(C(=O)O)c(=O)n(-c2ccc(F)cc2)c1,,CO,,Cl,[Na+].[OH-],test
US06358973B1,COc1cccc(C(CN)CC(C)C)c1.O=C(O)Cc1c(Cl)cncc1Cl>>COc1cccc(C(CNC(=O)Cc2c(Cl)cncc2Cl)CC(C)C)c1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US06358985B1,N#Cc1ccc(C(O)c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)cc1F>>N#Cc1ccc(C(=O)c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)cc1F,O=[Mn]=O,ClCCl,,,,test
US20110137045A1,CC(N)c1ccc(C2(C#N)CCCCC2)cc1.O=C(O)Cn1cnc2ccc(F)c(F)c21>>CC(NC(=O)Cn1cnc2ccc(F)c(F)c21)c1ccc(C2(C#N)CCCCC2)cc1,,CC#N,O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070010511A1,OCc1cccc(O)c1F.[C-]#N>>N#CCc1cccc(F)c1O,,O,,CN(C)C=O,,test
US05556864,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccccc1CCc1ccccc1>>CN1CCC[C@@H]1COc1ccccc1CCc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090312322A1,CSc1ncnc2cc(OCCOCCN3CCOCC3)ccc12.Cl.N#Cc1ccc2c(c1)CC(=O)N2>>Cl.N#Cc1ccc2c(c1)C(c1ncnc3cc(OCCOCCN4CCOCC4)ccc13)C(=O)N2,,CS(C)=O,O,[H-].[Na+],,test
US04654343,C#CCBr.CC(=O)Nc1cccc(-c2ccc3nnc(C)n3n2)c1>>C#CCN(C(C)=O)c1cccc(-c2ccc3nnc(C)n3n2)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20130225588A1,COC(=O)Cc1cc2ccc(F)cc2c(B2OC(C)(C)C(C)(C)O2)c1C.Clc1ccc(Sc2ccc(Br)cc2)cc1>>COC(=O)Cc1cc2ccc(F)cc2c(-c2ccc(Sc3ccc(Cl)cc3)cc2)c1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])O.[Na+],test
US05010204,Nc1nnc(SCc2ccccc2)s1.O=C(Cl)CCCCCl>>O=C(CCCCCl)Nc1nnc(SCc2ccccc2)s1,CN(C)c1ccncc1,ClC(Cl)Cl,ClCCl,CCN(CC)CC,CO,test
US20030139418A1,CCNCc1ccccc1Oc1ccccc1.NC(=O)c1ccc(Cl)nn1>>CCN(NCc1ccccc1Oc1ccccc1)C(=O)c1cccnn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20100048556A1,CCOC(=O)CCc1ncc[nH]1.Cc1ccc(F)c([N+](=O)[O-])c1>>CCOC(=O)CCc1nccn1-c1ccc(C)cc1[N+](=O)[O-],,CCOCC,,CC(=O)N(C)C,O=C([O-])[O-].[K+].[K+],test
US20070254877A1,O=C1CCCc2c1[nH]c1ccc(Cl)c([N+](=O)[O-])c21>>Nc1c(Cl)ccc2[nH]c3c(c12)CCCC3=O,[Zn],CCO,O,[Ca+2].[Cl-].[Cl-],,test
US20120065231A1,CC(C)(C)[Si](C)(C)OCC1CCCCN1.O=Cc1sc(Br)cc1Br>>CC(C)(C)[Si](C)(C)OCC1CCCCN1c1cc(Br)c(C=O)s1,,CN(C)C=O,,CCN(CC)CC,,test
US20090186879A1,CCC(CC)c1ccc(Cl)c2nc(Cl)n(CC(=O)OC(C)C)c12>>CCC(CC)c1ccc(Cl)c2nc(Cl)n(CCO)c12,,C1CCOC1,,[BH4-].[Li+],,test
US20120077814A1,CC(C)(C)Sc1ncnc2c(Br)csc12.CC1(C)OB(C2=CC(=O)CC2)OC1(C)C>>CC(C)(C)Sc1ncnc2c(C3=CC(=O)CC3)csc12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20150087663A1,CC[C@H](N)c1nc2cccc(Cl)c2c(=O)n1C1CC1.CCc1noc(-c2c(N)ncnc2Cl)n1>>CCc1noc(-c2c(N)ncnc2N[C@@H](CC)c2nc3cccc(Cl)c3c(=O)n2C2CC2)n1,,CCCCO,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20140256734A1,CC(C)(C)OC(=O)N1CCC[C@H]1CNc1nc(-c2n[nH]c(=O)[nH]2)cc2ccccc12>>O=c1[nH]nc(-c2cc3ccccc3c(NC[C@@H]3CCCN3)n2)[nH]1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020107251A1,O=[N+]([O-])c1cccc(/C=C/c2cccnc2)c1>>Nc1cccc(/C=C/c2cccnc2)c1,[Fe],CCO,,Cl,O=C([O-])O.[Na+],test
US05888422,CCCCCCCCCCOc1ccc(B(O)O)cc1.CCCCc1ccc2c(c1)C(F)(F)C(F)(F)C1=C2C=CC(Br)C1>>CCCCCCCCCCOc1ccc(-c2ccc3c(c2)C(F)(F)C(F)(F)c2cc(CCCC)ccc2-3)cc1,[Pd],,,,,test
US20090023708A1,C1CCNC1.Cc1ccc(S(=O)(=O)OCC2COC(=O)N2)cc1>>O=C1NC(CN2CCCC2)CO1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110009444A1,Nc1ccc(NC(=O)c2cc3cc(F)ccc3n2Cc2cccc(F)c2)cn1.O=C(CBr)c1cccs1>>O=C(Nc1ccc2nc(-c3cccs3)cn2c1)c1cc2cc(F)ccc2n1Cc1cccc(F)c1,,CC#N,,,,test
US03998807,CCCCCCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](CO)O[C@@H](n2ccc(N)nc2=O)[C@H]1O.Cl>>CCCCCCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](CO)O[C@@H](n2ccc(N)nc2=O)[C@H]1O.Cl,,CCO,,,,test
US05204462,Cc1cccc(NC(=O)[C@H](NC(=O)OCc2ccccc2)C(C)C)c1C(=O)O>>Cc1cccc(NC(=O)[C@H](N)C(C)C)c1C(=O)O,[Pd],CO,,O,,test
US05489303,CCCCC/C=C\C/C=C\CCCCCCCC(=O)O.ClP(Cl)(Cl)(Cl)Cl>>CCCCC/C=C\C/C=C\CCCCCCCC(=O)Cl,,c1ccccc1,,,,test
US20040192933A1,CC(=O)CCC(=O)O.CCCCCCCCCCN>>CCCCCCCCCCN1C(=O)CCC1C,,O,,,,test
US20050004149A1,N#CCc1ccncc1.O=Cc1cccc(F)c1>>N#C/C(=C/c1cccc(F)c1)c1ccncc1,,CCO,,Cl,[Na],test
US20150025095A1,Cc1[nH]c(=S)[nH]c(=O)c1C.O=C(O)CCl>>Cc1[nH]c(=O)[nH]c(=O)c1C,,O,,,,test
US20130029983A1,CCOC(=O)c1nn(-c2ccc(Cl)cc2)c(=O)c2c(N)scc12.O=C1CCC(=O)N1Cl>>CCOC(=O)c1nn(-c2ccc(Cl)cc2)c(=O)c2c(N)sc(Cl)c12,,CN(C)C=O,,O,,test
US06380218B1,CC(=O)c1ccc(CC(=O)Nc2cccnc2Oc2ccc(F)cc2)cc1.[Li]C>>CC(C)(O)c1ccc(CC(=O)Nc2cccnc2Oc2ccc(F)cc2)cc1,,C1CCOC1,,,,test
US20090137584A1,CC(C)(C)CC(=O)Cl.Nc1cc(Br)ccc1NCC1CC1>>CC(C)(C)CC(=O)Nc1cc(Br)ccc1NCC1CC1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,,test
US20080255202A1,CCOC(=O)C=O.NNCc1ccccc1F>>CCOC(=O)C=NNCc1ccccc1F,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20140187423A1,CCCCC(O)(Cn1cncn1)c1ccc(Oc2ccc(Cl)cc2)cc1Cl.CI>>CCCCC(Cn1cncn1)(OC)c1ccc(Oc2ccc(Cl)cc2)cc1Cl,,C1CCOC1,ClCCl,O,[H-].[Na+],test
US20040106641A1,COc1cccc(Cn2ccc3cccnc32)c1.O=C(Cl)C(=O)Cl>>COc1cccc(Cn2cc(C(=O)C(=O)Cl)c3cccnc32)c1,,COC(C)(C)C,,,,test
US20040254181A1,COC(=O)N=C(NC(=O)OC)SC.COC(=O)c1[nH]cc(Cc2cccnc2)c1N>>COC(=O)NC(=N)N(C(=O)OC)c1c(Cc2cccnc2)c[nH]c1C(=O)OC,,CC#N,,CCN(CC)CC,,test
US20130065906A1,O=C(O)c1ccc(-c2ccncc2)cc1.c1ccc(-c2noc(N3CCC(NC4CC4)CC3)n2)cc1>>O=C(c1ccc(-c2ccncc2)cc1)N(C1CC1)C1CCN(c2nc(-c3ccccc3)no2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US06153768,CCCCCSCCCCCCCCCC1c2ccc(O)cc2SCC1(C)c1ccc(O)cc1.CO>>CCCCCS(=O)CCCCCCCCCC1c2ccc(O)cc2SCC1(C)c1ccc(O)cc1,,CO,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US05841000,BrBr.C1=Cc2ccccc2C1.OO>>O[C@@H]1c2ccccc2C[C@H]1Br,,Clc1ccccc1,,O,,test
US20030022887A1,C1CNCCN1.COc1cc(-c2cc(CCl)ccn2)cc(OC)c1OC>>COc1cc(-c2cc(CN3CCNCC3)ccn2)cc(OC)c1OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140023611A1,COCCOCCOCCOCCOCCOCCOCCN(CCOC)CCN(C)C(=O)OCc1ccccc1>>CNCCN(CCOC)CCOCCOCCOCCOCCOCCOCCOC,[Pd],CO,,,,test
US20080221108A1,CC(C)(C)OC(=O)N1CCC(CC(=O)O)CC1.COC(=O)c1ccccc1N>>COC(=O)c1ccccc1NC(=O)CC1CCN(C(=O)OC(C)(C)C)CC1,,CC#N,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06248736B1,CI.O=C(NCc1ccc(Cl)cc1)c1cnc2ccc(C#CCO)cc2c1O>>Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(C#CCO)ccc21,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05457121,COC(=O)[C@@H]1CN(C)C[C@@H]1C(=O)OC>>CN1C[C@H](CO)[C@H](CO)C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110275673A1,CC(C)CCCCC#Cc1ccc(NC(=O)OC(C)(C)C)cc1>>CC(C)CCCCCCc1ccc(NC(=O)OC(C)(C)C)cc1,[Pd],CCOC(C)=O,,,,test
US20150266837A1,COc1ccc(Cn2nnnc2Br)cc1.NN>>COc1ccc(Cn2nnnc2NN)cc1,,CC(C)O,,O,,test
US20130137687A1,CC[C@@H](C(=O)N(C)OC)N(Cc1ccccc1)Cc1ccccc1>>CC[C@@H](C=O)N(Cc1ccccc1)Cc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060094767A1,O=C1NC(=O)c2ccccc21.OCC=Cc1ccc(C(F)(F)F)cc1>>O=C1NC(=O)C2(CC=Cc3ccc(C(F)(F)F)cc3)C=CC=CC12,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140315888A1,CC1CNCC(C)N1C.Clc1cnc2nc(Cl)c(Cl)nc2c1>>CC1CN(c2nc3ncc(Cl)cc3nc2Cl)CC(C)N1C,,ClCCl,,[Cl-].[NH4+],,test
US20050143381A1,COc1cnn(Cc2ccccc2)c(=O)c1Cl>>O=c1c(Cl)c(O)cnn1Cc1ccccc1,,O,,Cl,[K+].[OH-],test
US04411900,CC(=O)N(C)c1nc(CCl)cs1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>CC(=O)N(C)c1nc(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)cs1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04159984,COC(=O)C1NC2C(=O)N(C(C(=O)OC(c3ccccc3)c3ccccc3)=C(C)C)C2O1.O=C(Cl)Cc1ccccc1>>COC(=O)C1NC2(C(=O)Cc3ccccc3)C(=O)N(C(C(=O)OC(c3ccccc3)c3ccccc3)=C(C)C)C2O1,,ClCCl,,CCN(CC)CC,,test
US20150336892A1,ClCCl.NCCOCCOCCN.O=C(OC(=O)C(F)(F)F)C(F)(F)F.O=S(=O)(Cl)c1ccc(Oc2ccccc2)cc1>>O=C(NCCOCCOCCNS(=O)(=O)c1ccc(OCc2ccccc2)cc1)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20050038098A1,Cc1cc2c(cc1-c1cc(C3OCCO3)ccc1OC(F)(F)F)C(=O)CCC2(C)C.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1cc2c(cc1-c1cc(C3OCCO3)ccc1OC(F)(F)F)C(OS(=O)(=O)C(F)(F)F)=CCC2(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20050245588A1,C[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CC[C@H]1C2=CC[C@@H](C(F)(F)F)[C@@H]1N.O=Cc1ccccc1>>C[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CC[C@H]1C2=CC[C@@H](C(F)(F)F)[C@@H]1NCc1ccccc1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20120184747A1,CN(Cc1ccccc1)c1ccc(CC(NS(=O)(=O)c2cccnc2)c2cccc(N(CC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n2)cc1>>CN(Cc1ccccc1)c1ccc(CC(NS(=O)(=O)c2cccnc2)c2cccc(NCC(=O)O)n2)cc1,,ClCCl,,C1COCCO1,Cl,test
US20100160308A1,COc1cc([N+](=O)[O-])c(Nc2nc(-c3cccc(Cl)c3)c(C(N)=O)s2)cc1C(OC)OC>>COc1cc([N+](=O)[O-])c(Nc2nc(-c3cccc(Cl)c3)c(C(N)=O)s2)cc1C=O,,CC#N,,Cl,,test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1Cl.Cn1ccc2ccc(B3OC(C)(C)C(C)(C)O3)cc21>>CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1-c1ccc2ccn(C)c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,CCN(C(C)C)C(C)C,,test
US20130059849A1,CNS(=O)(=O)c1ccc(B(O)O)cc1.Cc1cc(C)c(CNC(=O)c2cc(Cl)nc3c2c(C)nn3C(C)C)c(=O)[nH]1>>CNS(=O)(=O)c1ccc(-c2cc(C(=O)NCc3c(C)cc(C)[nH]c3=O)c3c(C)nn(C(C)C)c3n2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,O=C([O-])O.[Na+],,test
US20140099316A1,CCCC1(C(=O)OCC)CCN(C(=O)OC(C)(C)C)CC1>>CCCC1(C(=O)OCC)CCNCC1,,C1COCCO1,,Cl,,test
US20030153570A1,Cc1ccc(Cl)cc1I.Clc1nc(Cl)nc(Cl)n1>>Cc1ccc(Cl)cc1-c1nc(Cl)nc(Cl)n1,,C1CCOC1,,II,[Mg],test
US20100160255A1,CC(C)(C)OC(=O)c1cc(Br)cc(I)c1.OB(O)c1cccnc1>>CC(C)(C)OC(=O)c1cc(Br)cc(-c2cccnc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US20120270881A1,CC(=O)OC(C)=O.Cc1c(C(=O)O)c2cc(O)ccc2n1C>>CC(=O)Oc1ccc2c(c1)c(C(=O)O)c(C)n2C,,CCOC(C)=O,ClCCl,Cl,c1ccncc1,test
US20100305133A1,CCOC(=O)CNC(=O)c1c(O)ccc2nc(-c3ccccc3)c(-c3nccs3)nc12>>O=C(O)CNC(=O)c1c(O)ccc2nc(-c3ccccc3)c(-c3nccs3)nc12,,CCO,,[Na+].[OH-],,test
US20050147778A1,CCC(O)COC(C)C.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCC(COC(C)C)OC(=O)C(F)(F)F,,ClCCl,,,,test
US03951976,CS(=O)(=O)c1nnc(N)s1.O=C(Cl)Cl>>CS(=O)(=O)c1nnc(N=C=O)s1,,CCOC(C)=O,,,,test
US20040192653A1,CC(C)CBr.COc1ccc2[nH]ncc2c1>>COc1ccc2c(cnn2CC(C)C)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04029491,CNCC=O.Cc1ccc2sc(N=C=O)nc2c1>>Cc1ccc2sc(NC(=O)N(C)CC=O)nc2c1,,c1ccccc1,,,,test
US20070191340A1,CC(=O)Cl.FC(F)(F)c1ccccc1-c1ccc(CN2CCN[C@@H](Cc3ccccc3)C2)cc1>>CC(=O)N1CCN(Cc2ccc(-c3ccccc3C(F)(F)F)cc2)C[C@@H]1Cc1ccccc1,,ClCCl,ClCCl,CCN(C(C)C)C(C)C,,test
US04547506,CN(CCCN)c1ccccn1.CSc1ncc(Cc2ccc(O)cc2)c(=O)[nH]1>>CN(CCCNc1ncc(Cc2ccc(O)cc2)c(=O)[nH]1)c1ccccn1,,c1ccncc1,,,,test
US20070149525A1,C=C(c1cccc(C2(NCC(O)C(Cc3cc(F)cc(F)c3)NC(C)=O)CC2)c1)C(F)(F)F>>CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(C(C)C(F)(F)F)c2)CC1,[Pd],CCOC(C)=O,,,,test
US20040220189A1,CNc1nccn2c(Br)cnc12>>CNc1nccn2ccnc12,[Pd],CO,,,,test
US20110118330A1,C=O.CC(C)(C)[Si](O[C@H](CO)CCCO)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](O[C@H]1CCCOCOC1)(c1ccccc1)c1ccccc1,,CCOC(C)=O,,CCOCC,FB(F)F,test
US20070129338A1,COB(OC)OC.COc1ccc(C)cc1Br>>COc1ccc(C)cc1B(O)O,,C1CCOC1,,Cl,[Li]CCCC,test
US20050032846A1,CC[C@H](N)CO.Cc1cc(C)c(Oc2nc(C)nc(Cl)c2C)c(C)c1>>CC[C@@H](CO)Nc1nc(C)nc(Oc2c(C)cc(C)cc2C)c1C,,CS(C)=O,,,,test
US20110230458A1,CCCCc1nnc(Cl)cc1-c1ccc(OC2CCCCC2)cc1.OC1CN2CCC1CC2>>CCCCc1nnc(OC2CN3CCC2CC3)cc1-c1ccc(OC2CCCCC2)cc1,,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US05763465,CSC1C(=O)Nc2c(OCc3ccccc3)ccc(CCN(CCCCCCOCCc3ccccc3)Cc3ccccc3)c21>>O=C1Cc2c(CCN(CCCCCCOCCc3ccccc3)Cc3ccccc3)ccc(OCc3ccccc3)c2N1,[Ni],CCO,,,,test
US20090029994A1,CCOC(=O)CCCCCN(CC)c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(OCCOC)cn1>>CCN(CCCCCC(=O)O)c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(OCCOC)cn1,,C1CCOC1,CCO,O=C(O)CC(O)(CC(=O)O)C(=O)O,[Na+].[OH-],test
US20090291079A1,CC(C)(C)OC(=O)N1CC(CNc2nc(Cl)nc(N3CCOCC3)n2)C1.CC1(C)OB(c2ccc(N)cc2)OC1(C)C>>CC(C)(C)OC(=O)N1CC(CNc2nc(-c3ccc(N)cc3)nc(N3CCOCC3)n2)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US05091587,C=CC(=C)C.COCCOCCOC.O.c1cnc2c(c1)ccc1cccnc12>>C=CC(=C)C.CC(=O)C(C)C,,O,,,,test
US04082771,CC(C)C(=O)Cl.COC(=O)c1cc(C)sc1N>>COC(=O)c1cc(C)sc1NC(=O)C(C)C,,CN(C)P(=O)(N(C)C)N(C)C,,O,,test
US20090156823A1,Br.CN[C@H]1CCN(S(=O)(=O)c2cccc3cncc(Cl)c23)C1>>Br.CN[C@H]1CCN(S(=O)(=O)c2cccc3cncc(Cl)c23)C1,,CCO,,,,test
US20120149676A1,CNc1cc(F)c(C(=O)Nc2ccc(F)c(Cl)c2)cc1[N+](=O)[O-].FC1CCNCC1>>CNc1cc(N2CCC(F)CC2)c(C(=O)Nc2ccc(F)c(Cl)c2)cc1[N+](=O)[O-],,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20150111870A1,COc1nc2ccc(C(O)(c3cnnn3C)C3CN(C(=O)OC(C)(C)C)C3)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1.CS(=O)(=O)Cl>>COc1nc2ccc(C(O)(c3cnnn3C)C3CN(S(C)(=O)=O)C3)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110275838A1,CCCCCCCCCCCCC(O)(C(=O)OC)C(=O)C(=O)OC.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCCCCCCCCCC(O)(C(=O)OC)/C(=C/C(=O)OC)C(=O)OC,,ClCCl,,,,test
US20130005707A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cccc2nc(N)nn12>>Cc1cccc2nc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nn12,CN(C)c1ccncc1,CC#N,,,,test
US05162325,CCCCC1Nc2ccc(C)cc2C(=O)N1Cc1ccc(-c2ccncc2C#N)cc1.C[Sn](C)(C)N=[N+]=[N-]>>CCCCc1nc2ccc(C)cc2c(=O)n1Cc1ccc(-c2ccncc2-c2nnn[nH]2)cc1,,Cc1ccccc1,,,,test
US20160168122A1,Cc1cc(C(C)(C)C)cc(F)c1C(=O)O.N>>Cc1cc(C(C)(C)C)cc(F)c1C(N)=O,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20130237545A1,COC(=O)C(N)CO.Cc1nnc(-c2ccccc2)c(C(=O)O)c1-c1ccccc1>>COC(=O)C(CO)NC(=O)c1c(-c2ccccc2)cnnc1-c1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160145255A1,CO.COc1ccc(Cn2nc(CO)cc(Br)c2=O)cc1>>COc1ccc(Cn2nc(CO)cc(OC)c2=O)cc1,,O,,[K+].[OH-],,test
US20150126488A1,COCOc1ccccc1C1CCC1>>Oc1ccccc1C1CCC1,,CO,,CCOC(C)=O,Cl,test
US06706725B1,CCC1(c2ccc(CO)s2)OCCO1.CS(=O)(=O)Cl>>CCC1(c2ccc(COS(C)(=O)=O)s2)OCCO1,,ClCCl,,CCN(CC)CC,[Cl-].[NH4+],test
US20150045355A1,CC(C)(C)[Si](C)(C)Oc1ccc(N)c([N+](=O)[O-])c1>>CC(C)(C)[Si](C)(C)Oc1ccc(N)c(N)c1,[Fe],CCO,,CC(=O)O,,test
US20030032623A1,CCCCCN(CCC12CC3CC(CC(C3)C1)C2)C(=O)NCCCc1ccncc1.Cl>>CCCCCN(CCC12CC3CC(CC(C3)C1)C2)C(=O)NCCCc1ccncc1.Cl,,ClC(Cl)Cl,,CCOC(C)=O,,test
US20130012485A1,CC(C)(C)OC(=O)NCC1(c2cccc(Cl)c2)CCC2(CC1)OCCO2>>CC(C)(C)OC(=O)NCC1(c2cccc(Cl)c2)CCC(=O)CC1,,CC(C)=O,O,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20090048213A1,CCOC(=O)[C@@H](CCC(=O)c1ccc(Cl)cc1)NC(=O)OC(C)(C)C>>CCOC(=O)[C@H]1CCC(c2ccc(Cl)cc2)=N1,,CCOC(C)=O,,Cl,O=C([O-])O.[Na+],test
US20080039459A1,CC(C)(N)c1cc2nc(Cl)nc(N3CCOCC3)c2s1.CC1(C)OB(c2cccc3[nH]ncc23)OC1(C)C.COc1cccc(C(=O)Cl)c1>>COc1cccc(C(=O)NC(C)(C)c2cc3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3s2)c1,,ClCCl,,CCN(CC)CC,,test
US20080171732A1,CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccccc3)CC2)nc1COCc1ccc(OC)c(OC)c1>>CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccccc3)CC2)nc1CO,,ClCCl,O,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20130196974A1,CC(C)(C)OC(=O)NCCN.Cc1ccc2nc(Cl)nc(Cl)c2c1>>Cc1ccc2nc(Cl)nc(NCCNC(=O)OC(C)(C)C)c2c1,,CO,,,,test
US20030036534A1,COC(=O)c1ccc(COc2cccc(CCSC(C)=O)c2C(=O)OC)cc1>>O=C(O)c1ccc(COc2cccc(CCS)c2C(=O)O)cc1,,CCO,,[K+].[OH-],,test
US04943580,CCOC(=O)N1CCCC(N)CC1.S=C=S>>CCOC(=O)N1CCCC(N=C=S)CC1,,C1CCOC1,,,,test
US20110294838A1,CCS(=N)(=O)c1ccc([N+](=O)[O-])cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCS(=O)(=NC(=O)C(F)(F)F)c1ccc([N+](=O)[O-])cc1,,ClCCl,,CCN(CC)CC,,test
US20070185171A1,CC1(C)CNC(=O)c2cc(N)ccc21.O=C(Cl)c1cccnc1F>>CC1(C)CNC(=O)c2cc(NC(=O)c3cccnc3F)ccc21,,ClCCl,,O=C([O-])O.[Na+],,test
US20160272634A1,CC(C)(C)OC(=O)C(C)(C)N.COC(=O)c1ccc(Br)cc1CBr>>CC(C)(C)OC(=O)C(C)(C)N1Cc2cc(Br)ccc2C1=O,,CC(C)(C)O,,CCN(CC)CC,,test
US20120021016A1,Cc1ccc(NC2(C#N)CCCCC2)cc1.N#CO[Na].O>>Cc1ccc(N2C(=O)NC(=O)C23CCCCC3)cc1,,CC(=O)O,,Cl,,test
US20030083267A1,CC1(C)NC(=O)c2ccccc2O1.O=P(Cl)(Cl)Cl>>CC1(C)NC(Cl)c2ccccc2O1,,O=P(Cl)(Cl)Cl,,ClP(Cl)(Cl)(Cl)Cl,,test
US20070129334A1,CC(=O)OCCn1c(Sc2cc3ccccc3[nH]2)nc2c(N)ncnc21.CCCI>>CCCn1c(Sc2nc3c(N)ncnc3n2CCOC(C)=O)cc2ccccc21,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20080021024A1,COC(=O)c1cc(CBr)ncn1.Cc1c(C(=O)OC(C)(C)C)ccc2c1CCC2N>>COC(=O)c1cc(CNC2CCc3c2ccc(C(=O)OC(C)(C)C)c3C)ncn1,,CN(C)C=O,,CCN(CC)CC,,test
US20100240634A1,CCOC(=O)c1ccccc1-c1ccc(C)cc1Cl>>Cc1ccc(-c2ccccc2C(=O)O)c(Cl)c1,,CCO,,[Na+].[OH-],,test
US06121202,Cc1cc(F)nc(Br)c1.Oc1csc(C(F)(F)F)c1>>Cc1cc(Br)nc(Oc2csc(C(F)(F)F)c2)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100173835A1,CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120184574A1,CC(C)OB(OC(C)C)OC(C)C.N#Cc1cn(C2CCC2)c2cc(OC(F)F)ccc12>>N#Cc1c(B(O)O)n(C2CCC2)c2cc(OC(F)F)ccc12,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20070203133A1,C[C@H]1COC[C@@H](C)N1.FC(F)(F)c1ccc2c(c1)Oc1c(CCl)nc3nc(-c4ncccc4C(F)(F)F)ccc3c1N2>>C[C@H]1CN(Cc2nc3nc(-c4ncccc4C(F)(F)F)ccc3c3c2Oc2cc(C(F)(F)F)ccc2N3)C[C@@H](C)O1,,CC(=O)N(C)C,,CCOC(C)=O,,test
US20050209260A1,Cc1cn(C)c2cc(C(C)C)c(OCc3ccccc3)cc12>>Cc1cn(C)c2cc(C(C)C)c(O)cc12,[Pd],CO,,,,test
US20150284367A1,Cc1cccc(Nc2cc(N[C@@H]3CCCC[C@@H]3NC(=O)OC(C)(C)C)ccc2C#N)n1.OO>>Cc1cccc(Nc2cc(N[C@@H]3CCCC[C@@H]3NC(=O)OC(C)(C)C)ccc2C(N)=O)n1,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20090143353A1,COc1c(Br)c(I)c(C)c(C#N)c1NC(=O)C(C)(C)C.OB(O)c1cccc(OCc2ccccc2)c1>>COc1c(Br)c(-c2cccc(OCc3ccccc3)c2)c(C)c(C#N)c1NC(=O)C(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20080234270A1,CCOC(=O)c1c[nH]cc1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1c[nH]c(Br)c1C,,C1CCOC1,,,,test
US20110166129A1,BrP(Br)Br.OCc1cccc(Br)n1>>BrCc1cccc(Br)n1,,ClCCl,,,,test
US20030013846A1,COCOc1ccc(CBr)cc1OCOC.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>COCOc1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1OCOC.[Br-],,Cc1ccccc1,,,,test
US20080262050A1,C=CCOc1cc2onc(OCC=C)c2cc1N1CC(=O)NS1(=O)=O>>C=CCOc1noc2cc(O)c(N3CC(=O)NS3(=O)=O)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20120077847A1,COC(=O)C(CCCCCCc1scnc1C)OC1CCCCC1>>COC(=O)C(O)CCCCCCc1scnc1C,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100152165A1,COC(=O)c1ccc2c(c1C)N(c1ccc(O)cc1)CCC2.Cc1ccc(S(=O)(=O)OCCC(C)(C)O)cc1>>COC(=O)c1ccc2c(c1C)N(c1ccc(OCCC(C)(C)O)cc1)CCC2,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130203815A1,COc1cc(OC)c(C=O)c(OC)c1.C[N+](=O)[O-]>>COc1cc(OC)c(C=C[N+](=O)[O-])c(OC)c1,,CC(=O)O,,C,O=C[O-].[NH4+],test
US05470878,Br.CC(=O)O.Cn1cnc2c1c(=O)n(CCCCCCCCCC(O)CO)c(=O)n2C>>CC(=O)OC(CBr)CCCCCCCCCn1c(=O)c2c(ncn2C)n(C)c1=O,,CC(=O)O,,ClCCl,O=C([O-])O.[Na+],test
US20140018319A1,CN1CCN(C2CN(C(=O)OCc3ccccc3)C2)CC1>>CN1CCN(C2CNC2)CC1,[Pd],CO,,,,test
US20060046980A1,CN(C)c1cc(Br)ccc1O.COCCl>>COCOc1ccc(Br)cc1N(C)C,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20100267688A1,CC1(C)OB(C2=CCC3(CC2)OCCO3)OC1(C)C.Oc1cccnc1I>>Oc1cccnc1C1=CCC2(CC1)OCCO2,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20030229094A1,C1=C(c2ccccn2)CCNC1.C=O.Cc1cc(C)cc(C(N)=O)c1>>Cc1cc(C)cc(C(=O)NCN2CC=C(c3ccccn3)CC2)c1,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US05000775,CCOC(=O)c1sc(Cl)nc1C(F)(F)F.NC(c1ccccc1)c1ccccc1>>CCOC(=O)c1sc(NC(c2ccccc2)c2ccccc2)nc1C(F)(F)F,,Cc1ccccc1,,,,test
US20120258950A1,NC(=O)CBr.O=C(Cc1ccc(Cl)cc1)Nc1cncc(C(=O)c2c[nH]c3ncncc23)c1>>NC(=O)Cn1cc(C(=O)c2cncc(NC(=O)Cc3ccc(Cl)cc3)c2)c2cncnc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020156081A1,Clc1ncnc2c1c(Br)nn2C1CCC2(CC1)OCCO2.N>>Nc1ncnc2c1c(Br)nn2C1CCC2(CC1)OCCO2,,C1COCCO1,,,,test
US20080139558A1,Cc1ncsc1S(=O)(=O)Nc1cccc(Cl)c1.O=c1cc(CBr)c2cccc(F)c2[nH]1>>Cc1ncsc1S(=O)(=O)N(Cc1cc(=O)[nH]c2c(F)cccc12)c1cccc(Cl)c1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120029190A1,COc1ccc(-c2nc3c(o2)CCNC3)cc1.Clc1cnccn1>>COc1ccc(-c2nc3c(o2)CCN(c2cnccn2)C3)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20040067935A1,CC(C)(C)OC(=O)N1CCCC(CNC(=O)OCc2ccccc2)C1.Cl>>Cl.O=C(NCC1CCCNC1)OCc1ccccc1,,CCOC(C)=O,,C1COCCO1,,test
US20110105461A1,CCOC(=O)C1CCc2ccc(S[Si](C(C)C)(C(C)C)C(C)C)cc2O1>>CCOC(=O)C1CCc2ccc(S)cc2O1,,CCO,,Cl,,test
US20090131530A1,BrBr.COc1ccc(Cc2ccc(NS(C)(=O)=O)cc2)cc1>>COc1ccc(Cc2ccc(NS(C)(=O)=O)cc2)cc1Br,,CC(=O)O,,O=S([O-])O.[Na+],,test
US20110171739A1,O=Cc1ccc(O)cc1.OCCF>>O=Cc1ccc(OCCF)cc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030109527A1,CC(=O)c1c([N+](=O)[O-])ccc(Cl)c1S(N)(=O)=O.O=S(=O)(O)O>>NS(=O)(=O)c1c(Cl)ccc([N+](=O)[O-])c1O,,CO,,C[Si](C)(C)Cl,,test
US20050020592A1,CN1CCC(c2nc(-c3ccncc3)c([N+](=O)[O-])c(=O)n2C)CC1>>CN1CCC(c2nc(-c3ccncc3)c(N)c(=O)n2C)CC1,[Pd],CO,,,,test
US20090239955A1,C=CCc1cccc(Oc2cc(CC=C)cc(O)c2O)c1>>C/C=C/c1ccc(Oc2cc(/C=C/C)cc(O)c2O)cc1,Cl[Pd]Cl,CCOC(C)=O,CO,CCCCCC,,test
US20090035324A1,CCOC(=O)C(=O)NNC(C)=O>>CCOC(=O)c1nnc(C)o1,,ClCCl,,CCN(CC)CC,,test
US20110301133A1,COC(=O)c1ccc(N2CCCCC2C(=O)OC)c([N+](=O)[O-])c1>>COC(=O)c1ccc2c(c1)NC(=O)C1CCCCN21,[Zn],CCOC(C)=O,,Cl,,test
US20080167360A1,CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(F)cc2)CC(C)(C)C1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC1(C)CC(=C(c2ccc(F)cc2)c2ccc(OS(=O)(=O)C(F)(F)F)cc2)CC(C)(C)C1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20050014812A1,C=O.CCOC(=O)c1cccc(NCc2cc(C)c3nc(C)n(Cc4ccc(Cl)cc4Cl)c3c2)c1>>CCOC(=O)c1cccc(N(C)Cc2cc(C)c3nc(C)n(Cc4ccc(Cl)cc4Cl)c3c2)c1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20080070850A1,O=C(c1cc(OCc2ccccc2)c(OCc2ccccc2)c(OCc2ccccc2)c1)C(O)[C@H]1OC(O)[C@@](O)(C(=O)c2cc(OCc3ccccc3)c(OCc3ccccc3)c(OCc3ccccc3)c2)[C@](O)(C(=O)c2cc(OCc3ccccc3)c(OCc3ccccc3)c(OCc3ccccc3)c2)[C@@]1(O)C(=O)c1cc(OCc2ccccc2)c(OCc2ccccc2)c(OCc2ccccc2)c1>>O=C(c1cc(OCc2ccccc2)c(OCc2ccccc2)c(OCc2ccccc2)c1)C(O)[C@H]1O[C@H](O)[C@@](O)(C(=O)c2cc(OCc3ccccc3)c(OCc3ccccc3)c(OCc3ccccc3)c2)[C@](O)(C(=O)c2cc(OCc3ccccc3)c(OCc3ccccc3)c(OCc3ccccc3)c2)[C@@]1(O)C(=O)c1cc(OCc2ccccc2)c(OCc2ccccc2)c(OCc2ccccc2)c1,,C1CCOC1,CO,,,test
US05380732,OCCCCCCCCOc1ncc(C(F)(F)F)cc1C(F)(F)F>>O=CCCCCCCCOc1ncc(C(F)(F)F)cc1C(F)(F)F,,ClCCl,,CCN(CC)CC,CS(C)=O,test
US20070066588A1,C=C1CC(c2nc3ccc(Br)cc3s2)C1.O=[Os](=O)(=O)=O>>O=C1CC(c2nc3ccc(Br)cc3s2)C1,O=[Os](=O)(=O)=O,C1CCOC1,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US05166198,CCOP(=O)(CCCOn1cnc2c(N)ncnc21)OCC.C[Si](C)(C)Br>>Br.Nc1ncnc2c1ncn2OCCCP(=O)(O)O,,ClCCl,,,,test
US20040186118A1,CC(C)(C)[Si](C)(C)OCc1cnc(Nc2cccc([N+](=O)[O-])c2)nc1NCCCNC(=O)OCc1ccccc1>>CC(C)(C)[Si](C)(C)OCc1cnc(Nc2cccc(N)c2)nc1NCCCNC(=O)OCc1ccccc1,,CCO,,N,O,test
US20150158846A1,Cc1ccc(S(=O)(=O)OCCN(C)C(=O)OC(C)(C)C)cc1.Cn1cc(Br)cc(Nc2cccc(O)n2)c1=O>>CN(CCOc1cccc(Nc2cc(Br)cn(C)c2=O)n1)C(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100130540A1,Cn1c(=O)cc(-c2cccc(Br)c2)c2cc(C3(c4ccc(Cl)cc4)OCCO3)cnc21>>Cn1c(=O)cc(-c2cccc(Br)c2)c2cc(C(=O)c3ccc(Cl)cc3)cnc21,,C1COCCO1,,Cl,,test
US20090093462A1,Cc1cc(Br)ccc1N.O=C(O)c1ccncc1F>>Cc1cc(Br)ccc1Nc1cnccc1C(=O)O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20120208827A1,CC1(C)OB(c2ccc3occc3c2)OC1(C)C.O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(Br)cc3)nc3cc(F)ccc32)C1>>O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(-c4ccc5occc5c4)cc3)nc3cc(F)ccc32)C1,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04082751,CCCOc1ccccc1C(=N)OC.COS(=O)(=O)O.N>>CCCOc1ccccc1C(=N)N.COS(=O)(=O)O,,CCO,,,,test
US20040063938A1,CC(=O)Cl.Nc1ccncc1N>>CC(=O)Nc1cnccc1N.Cl,,CC(=O)N(C)C,,,,test
US20060058202A1,CCCCCCCC/C=C\CCCCCCCCN.O=C(Cl)CCl>>CCCCCCCC/C=C\CCCCCCCCNC(=O)CCl,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20090042890A1,CCOC(=O)c1nc(N[C@@H]2CC[C@H](O)CC2)nc2c1[nH]c(=O)n2-c1ccccc1OC.CCOC(=O)c1nc(N[C@H]2CC[C@@H](O)CC2)nc(Nc2ccccc2OC)c1N>>COc1ccccc1-n1c(=O)[nH]c2c(C(N)=O)nc(N[C@@H]3CC[C@H](O)CC3)nc21,,ClCCl,,,,test
US20050107377A1,Fc1ccc2c(-c3ccc(OC[C@H]4CO4)cc3)noc2c1.NCC(O)c1ccccc1>>OC(CNC[C@@H](O)COc1ccc(-c2noc3cc(F)ccc23)cc1)c1ccccc1,,CCO,CN(C)C=O,,,test
US07179823B1,CCCc1c(C=O)cnn1Cc1ccccc1.CCOC(=O)CP(=O)(OCC)OCC>>CCCc1c(/C=C/C(=O)OCC)cnn1Cc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20130336920A1,CC(C)(C)OC(=O)N1CCCNCC1.O=C(NCc1cccc(C(F)(F)F)c1)c1ccnc(-c2cc(N3CCCCC3)ccc2NC(=O)c2cccc(CBr)c2)c1>>CC(C)(C)OC(=O)N1CCCN(Cc2cccc(C(=O)Nc3ccc(N4CCCCC4)cc3-c3cc(C(=O)NCc4cccc(C(F)(F)F)c4)ccn3)c2)CC1,,CN(C)C=O,O,[I-].[K+],,test
US05373020,CC(Cc1ccc(O)c(O)c1)N1CC(c2cccc(Cl)c2)OC1=O.CCOC(=O)C(Br)(Br)C(=O)OCC>>CCOC(=O)C1(C(=O)OCC)Oc2ccc(C[C@@H](C)N3C[C@@H](c4cccc(Cl)c4)OC3=O)cc2O1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04009175,ClCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2.O=C1c2ccccc2C(=O)N1O>>O=C1c2ccccc2C(=O)N1OCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2,,CC(=O)N(C)C,,CCN(CC)CC,,test
US04649146,CCOC(=O)C(=O)CC(=O)c1ccccn1.ClCCl.O=S(=O)(Cl)Cl>>CCOC(=O)C(=O)C(Cl)C(=O)c1ccccn1.Cl,,ClCCl,,CCOCC,,test
US04740581,CO.NCCO.O=C1c2ccccc2-c2c(Cl)c(=O)[nH]c3cccc1c23>>Cn1c(=O)c(NCCO)c2c3c(cccc31)C(=O)c1ccccc1-2,,CO,,CC(=O)[O-].[Na+],,test
US04120969,O=C1N(C2CCCCC2)CC(CCl)C1(c1ccccc1)c1ccccc1.OC1(c2ccccc2)CCNCC1>>O=C1N(C2CCCCC2)CC(CN2CCC(O)(c3ccccc3)CC2)C1(c1ccccc1)c1ccccc1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20050080260A1,BrCCBr.CN1C(=O)c2ccc(N)cc2C1=O>>CN1C(=O)c2ccc(NCCBr)cc2C1=O,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US20100009975A1,CN(CCCN1CCSc2cc([N+](=O)[O-])ccc21)C(=O)OC(C)(C)C>>CN(CCCN1CCSc2cc(N)ccc21)C(=O)OC(C)(C)C,[Ni],CO,,NN,O,test
US06420365B1,CCOC(=O)C(=O)C(Br)Cc1cc(Br)ccc1OC.CCOC(=O)CCc1cc(Br)ccc1OC.Nc1cnccn1>>CCOC(=O)c1nc2ccccn2c1Cc1cc(Br)ccc1OC,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20140045852A1,CSCc1cccc([N+](=O)[O-])c1.O=C(OO)c1cccc(Cl)c1>>CS(=O)(=O)Cc1cccc([N+](=O)[O-])c1,,ClCCl,,O,O=C([O-])O.[Na+],test
US20030199478A1,CCN(CC)CCCOc1ccc(N)cc1.COc1cccc(-c2ccc3c(c2)NC(=O)C3=CO)c1>>CCN(CC)CCCOc1ccc(NC=C2C(=O)Nc3cc(-c4cccc(OC)c4)ccc32)cc1,,C1CCOC1,,,,test
US04110113,CCCCCCCCCCCCOc1ccc(OCCCCCCCCCCCC)c(NC(C)=O)c1.O=[N+]([O-])O>>CCCCCCCCCCCCOc1cc([N+](=O)[O-])c(OCCCCCCCCCCCC)cc1NC(C)=O,,CC(=O)O,,,,test
US04977273,CCOC(=O)CBr.O=[N+]([O-])c1nc(CC(F)(F)CO)c[nH]1>>CCOC(=O)COCC(F)(F)Cc1c[nH]c([N+](=O)[O-])n1,,C1CCOC1,,CCO,[H-].[Na+],test
US05773447,CC1(C)CN(C(=N)N)C(=O)N1.c1cncnc1>>N#Cc1cnc[nH]c1=O,,COCCOC,,CC(=O)O,,test
US20100016279A1,FC(F)(F)c1nnc2ccc(N3CCNCC3)nn12.O=S(=O)(Cl)c1ccc2ccccc2c1>>O=S(=O)(c1ccc2ccccc2c1)N1CCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1,,c1ccncc1,,,,test
US04175089,C=CCCCCCC.CC(=O)O>>CCCCCCC1CCC(=O)O1,,CC(=O)O,,CC(=O)[O-].[K+],,test
US20160168139A1,CCC(C(=O)Nc1ccc2c(c1)Sc1cccc(-c3cc(N4CCOCC4)cc(=O)[nH]3)c1S2)N1CCOCC1>>CCC(CNc1ccc2c(c1)Sc1cccc(-c3cc(N4CCOCC4)cc(=O)[nH]3)c1S2)N1CCOCC1,,C1CCOC1,,O,O=C([O-])O.[Na+],test
US20040175387A1,CC(C)(C)OC(=O)ON=C(C#N)c1ccccc1.NCC(=O)NCC(=O)O>>CC(C)(C)OC(=O)NCC(=O)NCC(=O)O,,C1COCCO1,,CCN(CC)CC,,test
US05153214,CCOC(=O)C(CCCCN)(CCCc1cccnc1)C(=O)OCC.O=S(=O)(Cl)c1ccc(Cl)cc1>>CCOC(=O)C(CCCCNS(=O)(=O)c1ccc(Cl)cc1)(CCCc1cccnc1)C(=O)OCC,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20050032871A1,CN(C)S(=O)(=O)c1ccc2c(c1)CC(=O)N2.Cc1[nH]c(C=O)c(CCC(=O)O)c1S(C)(=O)=O>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)N(C)C)cc32)c(CCC(=O)O)c1S(C)(=O)=O,,CCO,,C1CCNCC1,,test
US20130012518A1,Cc1cc(Nc2ncc3c(n2)CCN(c2cc([N+](=O)[O-])ccc2C)C3=O)ccc1N1CCN(C)CC1>>Cc1cc(Nc2ncc3c(n2)CCN(c2cc(N)ccc2C)C3=O)ccc1N1CCN(C)CC1,[Pd],CO,,C1CCOC1,,test
US20030060498A1,C=O.CNCCc1c(C)n(C)c2ccc(S(=O)(=O)c3ccccc3)cc12>>Cc1c(CCN(C)C)c2cc(S(=O)(=O)c3ccccc3)ccc2n1C,,CC#N,,Cl,[BH3-]C#N.[Na+],test
US04977155,CC(=O)C(C)=O.Nc1ccc2nc(O)c(O)nc2c1N>>Cc1nc2ccc3nc(O)c(O)nc3c2nc1C,,O,,,,test
US20110098302A1,CC(C(=O)O)c1cccc(O)c1.O=Cc1cc(C(F)(F)F)ccc1F>>CC(C(=O)O)c1cccc(Oc2ccc(C(F)(F)F)cc2C=O)c1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US04514213,COC(=O)c1ccc(-c2ccccc2)cc1S(N)(=O)=O.COC(=O)c1ccc(Oc2ccccc2)cc1S(N)(=O)=O.O=C=NS(=O)(=O)Cl>>COC(=O)c1cc(Oc2ccccc2)ccc1S(=O)(=O)N=C=O,,Clc1ccccc1,,,,test
US20160176850A1,O=C1CCNCC1.c1cnc2[nH]ccc2c1>>C1=C(c2c[nH]c3ncccc23)CCNC1,,CO,,[K+].[OH-],,test
US05453414,O=c1[nH]c(-c2ccccc2)nc(Oc2ccccc2)c1I>>O=c1cc(Oc2ccccc2)nc(-c2ccccc2)[nH]1,[Zn],CC(=O)O,,,,test
US20030130281A1,O=C1c2ccccc2C(=O)N1CCCc1c[nH]c(-c2ccccc2)n1>>NCCCc1c[nH]c(-c2ccccc2)n1,,CCO,,NN,O,test
US20150284392A1,CCCCNc1ncc2c(Br)n[nH]c2n1.O[C@H]1CC[C@H](Cl)CC1>>CCCCNc1ncc2c(Br)nn([C@@H]3CC[C@@H](O)CC3)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090306133A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CN)CC1.O=C(O)c1cc(Cl)nc(Cl)c1>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CNC(=O)c2cc(Cl)nc(Cl)c2)CC1,,CN(C)C=O,O,CN1CCOCC1,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20130123512A1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1C(=O)O2.CS(=O)(=O)O>>CS(=O)(=O)[O-].O=C1O[C@@H]2C[NH2+][C@H]1C2,,CCOC(C)=O,,,,test
US20070244125A1,C1CC(N2CCOCC2)CCN1.CCOC(=O)c1cc2cc(C(=O)O)ccc2[nH]1>>CCOC(=O)c1cc2cc(C(=O)N3CCC(N4CCOCC4)CC3)ccc2[nH]1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20100113462A1,C/C=C/c1c(C)cccc1C(=O)NC1(C(=O)OCC)Cc2ccc(F)cc2C1>>C/C=C/c1c(C)cccc1C(=O)NC1(C(=O)O)Cc2ccc(F)cc2C1,,CCO,,O,[K+].[OH-],test
US20160200704A1,Cc1cc(C(=O)[O-])cc(Cc2ccc3ncc(Cl)cc3c2)n1>>Cc1cc(C(=O)O)cc(Cc2ccc3ncc(Cl)cc3c2)n1,,C1CCOC1,O,[Li+].[OH-],,test
US20080287523A1,CS(=O)(=O)Cl.Nc1ccccc1.c1ccncc1>>Nc1ccc(S(N)(=O)=O)cc1,,ClCCl,,,,test
US20040010022A1,Cc1nc(N)oc1-c1cccc2ccccc12.O=C1CCC(=O)N1Cl>>Nc1nc(CCl)c(-c2cccc3ccccc23)o1,,ClCCl,,,,test
US20070099938A1,Cl.Nc1nccc(-c2cc(OCC(F)(F)F)ccc2OCC(F)(F)F)n1>>FC(F)(F)COc1ccc(OCC(F)(F)F)c(-c2ccnc(Cl)n2)c1,,CC(=O)O,,O=N[O-].[Na+],,test
US20060116357A1,O=c1nc[nH]c2cc(F)c(F)cc12.OCc1ccccc1>>O=c1nc[nH]c2cc(OCc3ccccc3)c(F)cc12,,CN(C)C=O,,O,[H-].[Na+],test
US20130035326A1,CC(C)(C)c1cc(NC(=O)Cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)no1.COCCNc1ccc(Br)cn1>>COCCNc1ccc(-c2ccc(CC(=O)Nc3cc(C(C)(C)C)on3)cc2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20060241172A1,C=CCBr.Oc1cccc(Cl)c1-c1ccccc1Cl>>C=CCOc1cccc(Cl)c1-c1ccccc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20060052420A1,N#CCBr.Oc1ccc2cc(-c3csc(-c4ccccc4)n3)ccc2c1Br>>N#CCOc1ccc2cc(-c3csc(-c4ccccc4)n3)ccc2c1Br,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150299189A1,COC(=O)c1cc(C2CC2)cnc1Nc1cc(-c2cccc(-c3ccccc3)c2)c2c(ccn2C)c1>>Cn1ccc2cc(Nc3ncc(C4CC4)cc3C(=O)O)cc(-c3cccc(-c4ccccc4)c3)c21,,C1CCOC1,CO,[Na+].[OH-],,test
US05731331,OC1(c2ccccc2)CCN(CCCCn2cnc3ccccc32)CC1>>C1=C(c2ccccc2)CCN(CCCCn2cnc3ccccc32)C1,,CCO,,Cl,,test
US20080188499A1,Cl.NC(=O)c1ccccc1N>>Cl.NC(=O)c1ccccc1N,,CO,,,,test
US20110190342A1,NC(Cc1cccnc1)C(=O)O.O=C(O)c1cc2cc(Cl)ccc2nc1Cl>>O=C(O)c1cc2cc(Cl)ccc2nc1NC(Cc1cccnc1)C(=O)O,,CS(C)=O,,,,test
US20090062251A1,CCNCC(=O)NCC.O=C(O)c1ccc2[nH]c3c(c2c1)CC(C1CCOCC1)CC3>>CCNC(=O)CN(CC)C(=O)c1ccc2[nH]c3c(c2c1)CC(C1CCOCC1)CC3,,CN(C)C=O,Cl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110003815A1,CON(C)C(=O)c1ccc(C2(c3ccc(OCc4ccccn4)cc3)CC3CCC2C3)cc1.C[Mg]Br>>CC(=O)c1ccc(C2(c3ccc(OCc4ccccn4)cc3)CC3CCC2C3)cc1,,C1CCOC1,,CCOCC,,test
US20080139534A1,CCCCCC(=O)OC(=O)CCCCC.N=C(NO)c1ccc(NC(=O)CCCC(=O)Nc2ccc(C(=N)NO)cc2)cc1>>CCCCCC(=O)ONC(=N)c1ccc(NC(=O)CCCC(=O)Nc2ccc(C(=N)NOC(=O)CCCCC)cc2)cc1,,CS(C)=O,,CCN(CC)CC,,test
US20110301161A1,CC(C)(C)n1c(-c2cc(C#N)ccc2-n2cncn2)nc2cc(-c3cnc(N)nc3)ccc21.OO>>CC(C)(C)n1c(-c2cc(C(N)=O)ccc2-n2cncn2)nc2cc(-c3cnc(N)nc3)ccc21,,CCOC(C)=O,CO,[NH4+].[OH-],,test
US20090163380A1,CC(C)(C)OC(=O)COCCOCCOCCOCCO.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)COCCOCCOCCOCCOS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US06100272,CC(=O)OC(C)=O.O=[N+]([O-])c1ccc2c(c1)NCC2>>CC(=O)N1CCc2ccc(N)cc21,[Pd],CCO,,,,test
US20060217382A1,CC(C)(C)C(=O)Nc1ccccc1C(=O)O.COc1cc(Nc2ncc(C(C)N)nn2)cc(OC)c1OC>>COc1cc(Nc2ncc(C(C)NC(=O)c3ccccc3NC(=O)C(C)(C)C)nn2)cc(OC)c1OC,,CN(C)C=O,,CCN(CC)CC,,test
US04732998,ClP(Cl)(Cl)(Cl)Cl.O=COCCCN1C(=O)c2ccccc2C1=O>>O=C1c2ccccc2C(=O)N1CCCOC(Cl)Cl,,CCOCC,,ClC(Cl)Cl,,test
US20110130412A1,CCOC(=O)[C@@H](O)[C@@H](NCc1cn(COCc2ccccc2)c2c(OC)ncnc12)C(=O)OCC>>COc1ncnc2c(CN[C@H](CO)[C@H](O)CO)cn(COCc3ccccc3)c12,,CCOCC,CO,[BH4-].[Li+],,test
US20090163520A1,CC(=O)Cl.Nc1ncnc2c1cnn2-c1cccc(-c2cnc[nH]2)c1>>CC(=O)n1cnc(-c2cccc(-n3ncc4c(N)ncnc43)c2)c1,,CN(C)C=O,,[H-].[Na+],,test
US04788206,NCCCCc1cccnc1.O=C(O)C=C=C=C(c1ccccc1)c1ccccc1>>O=C(/C=C/C=C(c1ccccc1)c1ccccc1)NCCCCc1cccnc1,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US20110046171A1,CCNC(=NS(=O)(=O)c1ccc(NC(C)=O)cc1)N1CC(C)(C)C=N1>>CCNC(=NS(=O)(=O)c1ccc(N)cc1)N1CC(C)(C)C=N1,,CO,,Cl,[Na+].[OH-],test
US20110269738A1,CCc1c(Br)cccc1C=C1CCN(C(=O)OC(C)(C)C)CC1>>CCc1c(Br)cccc1C=C1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090252676A1,C=CCOC(=O)NCCCCCCO.CS(=O)(=O)Cl>>C=CCOC(=O)NCCCCCCOS(C)(=O)=O,,ClCCl,,CCN(CC)CC,[Cl-].[NH4+],test
US20140179699A1,OCc1cc(Cl)ccc1Nc1cnnn1Cc1ccccc1>>OCc1cc(Cl)ccc1Nc1cn[nH]n1,[Pd],CO,,O=CO,,test
US05668128,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.CC(C)CCN>>CC(C)CCNC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20100190766A1,ClCCl.NC1CC1.O=C(O)c1ccc(C#C/C=C/c2ccc(CN3CCOCC3)cc2)cc1>>COC(=O)c1ccc(C#C/C=C/c2ccc(CNC3CC3)cc2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120309796A1,C=C(C)c1cc(C(F)(F)F)cc(S(=O)(=O)NC2CCCCc3c(OCC(=O)OC(C)(C)C)cccc32)c1>>CC(C)c1cc(C(F)(F)F)cc(S(=O)(=O)NC2CCCCc3c(OCC(=O)OC(C)(C)C)cccc32)c1,[Pd],CO,,,,test
US20130231328A1,COC(C[C@H]1CCc2sc3ncnc(OC4CCC(N(C)C(=O)OC(C)(C)C)CC4)c3c21)OC.C[Si](C)(C)C#N>>CNC1CCC(Oc2ncnc3sc4c(c23)[C@@H](CC(C#N)OC)CC4)CC1,,ClCCl,,CCOCC,FB(F)F,test
US20060155121A1,CC(C)(C)CC(=O)Cl.Cc1cc(Br)cc([N+](=O)[O-])c1N>>Cc1cc(Br)cc([N+](=O)[O-])c1NC(=O)CC(C)(C)C,,CC#N,,O,,test
US20140187553A1,Cc1ccc(S(=O)(=O)n2cc(I)c3cc(C(=O)O)ccc32)cc1.NNC(=O)c1ccccc1>>Cc1ccc(S(=O)(=O)n2cc(I)c3cc(C(=O)NNC(=O)c4ccccc4)ccc32)cc1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100113508A1,CN(C)CC#Cc1cc(N2C3CCC2CC3)ccc1[N+](=O)[O-]>>CN(C)CC#Cc1cc(N2C3CCC2CC3)ccc1N,[Fe],O,,,,test
US20040167182A1,CC(C)(C)OC(=O)C1(S(=O)(=O)c2ccc(-c3ccc(OC(F)(F)C(F)F)cc3)cc2)CCN(Cc2ccccc2)CC1.NOC1CCCCO1>>O=C(NOC1CCCCO1)C1(S(=O)(=O)c2ccc(-c3ccc(OC(F)(F)C(F)F)cc3)cc2)CCN(C2CC2)CC1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20140200207A1,CC(C)Oc1nc(Cl)nc2c1c(I)cn2COCC[Si](C)(C)C.[CH2+]C1(C)OB(c2ccc(-c3nccn3COCC[Si](C)(C)C)cc2)OC1(C)C>>CC(C)Oc1nc(Cl)nc2c1c(-c1ccc(-c3nccn3COCC[Si](C)(C)C)cc1)cn2COCC[Si](C)(C)C,,O,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20070069197A1,CCCCCCn1c2ccccc2c2ccc(CO)cc21>>CCCCCCn1c2ccccc2c2ccc(C=O)cc21,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20110034445A1,CCCCCOC(=O)Cl.Cn1cncc1C(=NOCc1nccc(N)n1)c1ccccc1>>CCCCCOC(=O)Nc1ccnc(CON=C(c2ccccc2)c2cncn2C)n1,,C1COCCO1,,CCN(CC)CC,,test
US20130096113A1,Cc1ccc(S(=O)(=O)OC2COC2)cc1.Nc1ccc(O)cc1[N+](=O)[O-]>>Nc1ccc(OC2COC2)cc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06194444B1,BrCc1ccccc1.Cc1nnsc1CO>>Cc1nnsc1COCc1ccccc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2c(OC)cccc23)cc1.Nc1ccc2c(c1)OCO2>>COc1cccc2c1nc(Nc1ccc3c(c1)OCO3)c1n[nH]cc12,C1COCCO1,CO,,Cl,,test
US20120116118A1,Cc1cc(C(C)(C)C)cc(C)c1CC(=O)O>>Cc1cccc(C)c1CC(=O)O,,ClCCl,,Cc1ccccc1,,test
US20150218124A1,N#Cc1cc(O)c(O)c(C#N)c1Br.Sc1ccccc1Cl>>N#Cc1cc(O)c(O)c(C#N)c1Sc1ccccc1Cl,[Zn],CN(C)C=O,,ClCCl,,test
US05292926,CC(C)(S)C(=O)N[C@@H](CS)C(=O)O.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(S)C(=O)N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O,,CN(C)C=O,,O,,test
US20130296308A1,CC=CC[C@H](COCc1ccccc1)OCC(OCC)OCC>>CC=CC[C@H](COCc1ccccc1)OCC=O,,C1CCOC1,,Cl,,test
US20060199951A1,CCCCCCBr.Cc1cccc(C)n1>>CCCCCC[n+]1ccc(C)cc1C.[Br-],,Cc1ccccc1,,ClC(Cl)Cl,,test
US20150322051A1,CCOCC(=O)OCCl.COc1ccnc(C(=O)N[C@H]2CCC[C@H](Cc3ccccc3)[C@@H](Cc3ccccc3)[C@H](C)OC2=O)c1O>>CCOCC(=O)OCOc1c(OC)ccnc1C(=O)N[C@H]1CCC[C@H](Cc2ccccc2)[C@@H](Cc2ccccc2)[C@H](C)OC1=O,,CC(C)=O,,[I-].[Na+],,test
US20060161001A1,c1ccc(-c2cc3ncccc3cn2)cc1>>c1ccc(-c2cc3c(cn2)CCCN3)cc1,[Pd],CO,,,,test
US20160081334A1,COC1=C(c2c(C)cc(-n3cc(Cl)cn3)cc2C)C(=O)CC1.N#CCBr>>COC1=C(c2c(C)cc(-n3cc(Cl)cn3)cc2C)C(=O)C(CC#N)C1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20060111375A1,CC(C)[Mg]Br.COc1cc2nccc(Oc3ccc(C)cc3C=O)c2cc1OC>>COc1cc2nccc(Oc3ccc(C)cc3C(O)C(C)C)c2cc1OC,,C1CCOC1,,[Cl-].[NH4+],,test
US05631208,CCCC(=O)O.Cc1c(C)c(C2CC(=O)CC(=O)C2)c(C)c2c1OC(C)(C)C2>>CCCC(=O)C1=C(O)CC(c2c(C)c(C)c3c(c2C)CC(C)(C)O3)CC1=O,CN(C)c1ccncc1,Cc1ccccc1,,,,test
US20160060257A1,CC(C)(C)OC(=O)N1CC=C(c2cc3c(-c4cc(NCc5cccnc5)ccc4Cl)ccnc3[nH]2)C1>>Clc1ccc(NCc2cccnc2)cc1-c1ccnc2[nH]c(C3=CCNC3)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110311461A1,COc1ccc(C(Nc2cccc(F)c2)C(=O)O)cn1.O[C@H]1CN2CCC1CC2>>COc1ccc(C(Nc2cccc(F)c2)C(=O)O[C@H]2CN3CCC2CC3)cn1,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20160002204A1,F[C@H](CBr)CCBr.N#Cc1ccc(N)cc1>>N#Cc1ccc(N2CC[C@H](F)C2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20010039285A1,COc1ccc2c(c1)CCN(C(=O)C(F)(F)F)C2c1cccs1>>O=C(N1CCc2cc(O)ccc2C1c1cccs1)C(F)(F)F,,ClCCl,,BrB(Br)Br,CO,test
US20110118245A1,COCCOc1cc2ncnc(Oc3cccc(N)c3)c2cc1OC.O=C(Nc1cc(C(F)(F)F)nn1-c1ccccc1)Oc1ccccc1>>COCCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(F)(F)F)nn4-c4ccccc4)c3)c2cc1OC,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20150175557A1,CC(C)(C)OC(=O)NCCc1ccc(C#N)c(OC(F)(F)F)c1>>N#Cc1ccc(CCN)cc1OC(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160159809A1,Clc1nc(NCC(c2ccncc2)c2ccncc2)c2ccccc2n1.c1cc2c([nH]1)CCNC2>>c1ccc2c(NCC(c3ccncc3)c3ccncc3)nc(N3CCc4[nH]ccc4C3)nc2c1,,CCO,,CO,ClC(Cl)Cl,test
US20100331315A1,COCCN.O=C1NC(=S)SC1=Cc1ccc(-c2ccc(Cl)c(C(=O)O)c2)o1>>COCCNC(=O)c1cc(-c2ccc(C=C3SC(=S)NC3=O)o2)ccc1Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04645527,NC1CCCC1.O=C=NS(=O)(=O)c1cccc(Cl)c1Cl>>O=C(NC1CCCC1)NS(=O)(=O)c1cccc(Cl)c1Cl,,CC#N,,,,test
US20120263649A1,CC(=O)OC[C@H]1O[C@H](O[C@H]2O[C@H](COC(C)=O)[C@@H](O)[C@H](OC(C)=O)[C@H]2OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.CCN(CC)S(F)(F)F>>CC(=O)OC[C@H]1O[C@H](O[C@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1F,CN(C)c1ccncc1,ClCCl,ClCCl,CCOC(C)=O,,test
US04554349,CC(=O)O[C@@H]1[C@@H](CN=[N+]=[N-])O[C@H](SCC=Cc2ccccc2)[C@@H](OC(C)=O)[C@H]1OC(C)=O>>[N-]=[N+]=NC[C@H]1O[C@H](SCC=Cc2ccccc2)[C@@H](O)[C@@H](O)[C@@H]1O,,CO,,C[O-].[Na+],,test
US04083989,BrCc1ccccc1.CC(C)(C)c1cccc(C(C)(C)C)c1O.S=C=S>>CC(C)(C)c1cc(C(=S)SCc2ccccc2)cc(C(C)(C)C)c1O,,CS(C)=O,,Cl,[K+].[OH-],test
US20090076070A1,NC(=O)c1ccc2ncsc2c1>>N#Cc1ccc2ncsc2c1,,O=P(Cl)(Cl)Cl,,,,test
US20100035902A1,CC(=O)C(=Cc1cccc2c(=O)cc(C)oc12)C(C)=O.Nc1cc(=O)[nH]cn1>>CC(=O)C1=C(C)Nc2nc[nH]c(=O)c2C1c1cccc2c(=O)cc(C)oc12,,CC(C)O,,,,test
US20070243568A1,Nc1nc(N)c(N)c(OCc2ccc(CNC(=O)C(F)(F)F)cc2)n1.OCC1(O)COC(O)(CO)CO1>>Nc1nc(OCc2ccc(CNC(=O)C(F)(F)F)cc2)c2nc(CO)cnc2n1,,CC(=O)N(C)C,O,O=C(CO)O[CH][C@@H](O)CO,C[O-].[Na+],test
US20070270587A1,CC(N=[N+]=[N-])C(C)N1C(=O)C2(OCCCO2)c2cc(S(=O)(=O)N3CCCC3)ccc21>>CC(N)C(C)N1C(=O)C2(OCCCO2)c2cc(S(=O)(=O)N3CCCC3)ccc21,[Pd],CO,,,,test
US20040138143A1,NCc1ccccc1.O=C(O)c1sccc1O>>O=C(NCc1ccccc1)c1sccc1O,,CC(=O)O,ClCCl,O=C([O-])O.[Na+],,test
US04367238,CC1C(=O)Oc2c(Sc3ccccc3Cl)cccc21.O=C(OO)c1cccc(Cl)c1>>CC1C(=O)Oc2c1cccc2S(=O)c1ccccc1Cl,,ClC(Cl)Cl,,,,test
US04116956,CC(C)CC1N=C(c2ccccc2)c2cc(Cl)ccc2N=C1NN.CCOC(OCC)OCC>>CC(C)CC1N=C(c2ccccc2)c2cc(Cl)ccc2-n2cnnc21,,CCO,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US04004912,CN1CCC(O)N(c2nnc(C3CCCCC3)s2)C1=O.O=C(Cl)c1ccccc1>>CN1CCC(OC(=O)c2ccccc2)N(c2nnc(C3CCCCC3)s2)C1=O,,c1ccccc1,,CCN(CC)CC,,test
US20070060582A1,CC(C)(C)c1ccc(N)cc1.Clc1cccc2ccnc(Cl)c12>>CC(C)(C)c1ccc(Nc2nccc3cccc(Cl)c23)cc1,,CCCCO,,Cl,O=C([O-])O.[Na+],test
US20130072677A1,CNCc1ccccc1.COC(=O)C(Br)C(=O)OC>>COC(=O)C(C(=O)OC)N(C)Cc1ccccc1,,Cc1ccccc1,,CC#N,,test
US20070135438A1,CC(=O)c1ccc(N)nc1.O=S(=O)(Cl)c1ccc(I)cc1>>CC(=O)c1ccc(NS(=O)(=O)c2ccc(I)cc2)nc1,,c1ccncc1,,Cl,,test
US20040038967A1,Brc1cncc(CN2CCOCC2)c1.O=Cc1ncn2ccsc12>>OC(c1cncc(CN2CCOCC2)c1)c1ncn2ccsc12,,CCCCCC,,,,test
US06048841,CCOC(=O)CCCCBr.O=C1CCC(=O)N1>>CCOC(=O)CCCCN1C(=O)CCC1=O,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04441913,CC(O)COCc1ccccc1.CC(Oc1ccc(Oc2ncc(Cl)cc2Cl)cc1)C(=O)Cl>>CC(COCc1ccccc1)OC(=O)C(C)Oc1ccc(Oc2ncc(Cl)cc2Cl)cc1,,Cc1ccccc1,,CCN(CC)CC,,test
US06972297B2,COC(=O)c1cc([N+](=O)[O-])ccn1>>COC(=O)c1cc(N)ccn1,[Pd],CO,,,,test
US20120289551A1,C1CCC2OC2C1.Fc1ccc([Mg]Br)cc1>>OC1CCCCC1c1ccc(F)cc1,,C1CCOC1,,,,test
US20120010228A1,CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccc(F)cc3)C3(CCN(C(=O)OCc4ccccc4)CC3)C2=O)c1>>CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccc(F)cc3)C3(CCNCC3)C2=O)c1,[Pd],CO,,,,test
US20090029976A1,COC(=O)CS.COc1cc(C=O)c(F)cc1Cl>>COC(=O)c1cc2cc(OC)c(Cl)cc2s1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080039504A1,CCOC(=O)c1nnc(-c2ncc(Cl)cc2NS(=O)(=O)c2ccc(Cl)c(C(F)(F)F)c2)n1C(C)C.CNC>>CC(C)n1c(C(=O)N(C)C)nnc1-c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1,,C1CCOC1,,CCOC(C)=O,,test
US20040087588A1,COC(=O)CCC(=O)ONC(=N)c1cccc(NC(=O)OC(C)(C)C)c1>>COC(=O)CCc1nc(-c2cccc(NC(=O)OC(C)(C)C)c2)no1,,Cc1ccccc1,,,,test
US06056895,BrC(Br)(Br)Br.CCC=C1CCC(CCO)CC1>>CCC=C1CCC(CCBr)CC1,,CC#N,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090264399A1,CCOC(=O)CP(=O)(OCC)OCC.O=C[C@H]1CCC[C@H](n2c(=O)[nH]c3cnc4[nH]ccc4c32)C1>>O=C(O)/C=C/[C@H]1CCC[C@H](n2c(=O)[nH]c3cnc4[nH]ccc4c32)C1,,C1CCOC1,,O,[H-].[Na+],test
US20040019048A1,CCCCN=C=O.CCCCc1nc2c(N)nc3ccccc3c2n1CCCN>>CCCCNC(=O)NCCCn1c(CCCC)nc2c(N)nc3ccccc3c21,,CN1CCCC1=O,O,CCN(CC)CC,O=C([O-])[O-].[K+].[K+],test
US20100160369A1,Nc1ccc(I)cn1.O=C1CCC(=O)N1Cl>>Nc1ncc(I)cc1Cl,,CN(C)C=O,,O,,test
US20030114495A1,Cn1cnc(-c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1Cl.O=C=NC1CCCCC1>>Cn1c(C(=O)NC2CCCCC2)nc(-c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1Cl,,C1CCOC1,,[Li]CCCC,,test
US20160222001A1,C[Si](C)(C)CCSc1cc(Cl)c(OCc2ccccc2)c2ncccc12.Fc1ccc(I)cc1>>Fc1ccc(Sc2cc(Cl)c(OCc3ccccc3)c3ncccc23)cc1,,C1COCCO1,,,,test
US20140274930A1,COC(=O)c1cccc(-c2ccc(O[C@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@]3(C)OC(C)=O)c(C)c2)c1>>COC(=O)c1cccc(-c2ccc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@]3(C)O)c(C)c2)c1,,CO,,C[O-].[Na+],,test
US20150329560A1,CC(C)[C@@H]1CSC(=S)N1C(=O)C[C@H](O)/C=C/CCSC(c1ccccc1)(c1ccccc1)c1ccccc1.C[Si](C)(C)CCOC(=O)CN(Cc1cccc(CN)n1)Cc1cccc2ccccc12>>C[Si](C)(C)CCOC(=O)CN(Cc1cccc(CNC(=O)C[C@H](O)/C=C/CCSC(c2ccccc2)(c2ccccc2)c2ccccc2)n1)Cc1cccc2ccccc12,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150152112A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C1CCc2nc(-c3cc(Cl)ccc3N)cc(=O)n21>>CC1CCc2nc(-c3cc(Cl)ccc3NC(=O)OC(C)(C)C)cc(=O)n21,,CC(C)(C)O,,,,test
US20150038528A1,CCOC(=O)c1ccc(Oc2ccccn2)cc1CN(CC(=O)OC)S(=O)(=O)c1ccc(C)cc1>>COC(=O)c1ncc2cc(Oc3ccccn3)ccc2c1O,,CN(C)C=O,,CC(=O)O,C[O-].[Na+],test
US05025025,COC(=O)CCCCC(Br)C(O)c1cccnc1>>COC(=O)CCCCC1OC1c1cccnc1,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20090311217A1,COc1ccc2[nH]c(Br)c(C=O)c2c1.N#CCCCCl>>COc1ccc2c(c1)c(C=O)c(Br)n2CCCC#N,,CN1CCCC1=O,,[H-].[Na+],,test
US04968340,CC(C)N.COc1cc(OC)nc(SC(C(=O)O)C2CCCC2)n1>>CC(C)[NH3+].COc1cc(OC)nc(SC(C(=O)[O-])C2CCCC2)n1,,CO,,,,test
US20140142085A1,CCc1[nH]nc(C(F)(F)F)c1Br.NC(=O)c1cc(-c2cccnc2[C@H](Cc2cc(F)cc(F)c2)NC(=O)CCl)ccc1F>>CCc1c(Br)c(C(F)(F)F)nn1CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1ncccc1-c1ccc(F)c(C(N)=O)c1,,CN(C)C=O,,CCOC(C)=O,CC(C)(C)[O-].[K+],test
US20120110702A1,O=[N+]([O-])c1cn(-c2cccnc2)nc1Cl.OB(O)c1ccccc1>>O=[N+]([O-])c1cn(-c2cccnc2)nc1-c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[K+].[K+],test
US20120108583A1,CC1(C)Cc2c(c(C(=O)O)cc3nc(Nc4c(Cl)cncc4Cl)[nH]c23)O1.Nc1ccc(C(F)(F)F)cc1>>CC1(C)Cc2c(c(C(=O)Nc3ccc(C(F)(F)F)cc3)cc3nc(Nc4c(Cl)cncc4Cl)[nH]c23)O1,,C1CCOC1,CN(C)C=O,CN1CCOCC1,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20010031753A1,COc1cc(C)cc(OC)c1OC.O=C(Br)c1ccccc1>>COc1cc(C)c(C(=O)c2ccccc2)c(OC)c1OC,,ClCCCl,,,,test
US05576321,O=C(O)C(=O)O.O=C1CCc2ccccc2C12CCNCC2.c1cc(OC[C@@H]2CO2)c2cc[nH]c2c1>>O=C(O)C(=O)O.O=C1CCc2ccccc2C12CCN(C[C@H](O)COc1cccc3[nH]ccc13)CC2,,CCOC(C)=O,,CO,,test
US04319031,CC1(C)NCCS1.O=C(Cl)C(Br)Br>>CC1(C)SCCN1C(=O)C(Br)Br,,CCN(CC)CC,,c1ccccc1,,test
US20100305336A1,CC(C)(O)C(=O)c1ccccc1.O=C(Cl)CCCl>>CC(C)(OC(=O)CCCl)C(=O)c1ccccc1,,C1CCOC1,,CCN(CC)CC,,test
US20070010670A1,O=C(Cl)c1cc(Br)c(O)c(Br)c1.c1ccc2c3c(ccc2c1)OCCN3>>O=C(c1cc(Br)c(O)c(Br)c1)N1CCOc2ccc3ccccc3c21,,CCOC(C)=O,,,,test
US04753953,C[C@H]1CN(Cc2ccccc2)C[C@H]1NC(=O)OC(C)(C)C>>C[C@H]1CNC[C@H]1NC(=O)OC(C)(C)C,[Pd],CCO,,[H][H],,test
US20160200716A1,CC(C)c1nc(CN(C)C(=O)N[C@@H](CCN2CCOCC2)C(=O)N[C@H](CC[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)Cc2ccccc2)cs1.CS(=O)(=O)O>>CC(C)c1nc(CN(C)C(=O)N[C@@H](CCN2CCOCC2)C(=O)N[C@H](CC[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)Cc2ccccc2)cs1.CS(=O)(=O)[O-],,COC(C)(C)C,,,,test
US20100160434A1,CCC(=CCOS(=O)(=O)c1ccc(C)cc1)C(F)(F)F.COC(=O)CS(=O)(=O)CCC(F)(F)F>>CCC(=CCC(C(=O)OC)S(=O)(=O)CCC(F)(F)F)C(F)(F)F,,CN(C)C=O,,Cl,[H-].[Na+],test
US05167949,COCOCc1nc(N)c2ncc(OC)nc2n1>>COCOCc1nc(N)c2ncc(O)nc2n1,,O,,[Na+].[OH-],,test
US20150225381A1,CN.COC(=O)COc1ccc(N2C(=S)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C2(C)C)cc1F>>CNC(=O)COc1ccc(N2C(=S)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C2(C)C)cc1F,,C1CCOC1,,,,test
US20090325925A1,N.N#Cc1c(N2CCOCC2)sc(C(=O)O)c1-c1ccc(Cl)cc1Cl>>N#Cc1c(N2CCOCC2)sc(C(N)=O)c1-c1ccc(Cl)cc1Cl,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20090143368A1,CC(=O)c1c(O)c2cccnc2n(C)c1=O.COCC(=O)Nc1cccc(C=O)c1>>COCC(=O)Nc1cccc(C=CC(=O)c2c(O)c3cccnc3n(C)c2=O)c1,,CCO,,C1CCNCC1,,test
US20060009509A1,CC1(C)C(=O)Nc2ccc(Br)c(F)c21.Cn1c(C#N)ccc1B(O)O>>Cn1c(C#N)ccc1-c1ccc2c(c1F)C(C)(C)C(=O)N2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20070281979A1,CS(=O)(=O)O.Cc1cc(S(N)(=O)=O)ccc1-c1ccc(F)nc1.Nc1ncc(Br)s1.O=C(Cl)Oc1ccccc1>>COc1ccc(-c2ccc(S(=O)(=O)NC(=O)Nc3ncc(Br)s3)cc2C)cn1,,CC#N,,CCN(CC)CC,O,test
US20090203737A1,CC(C)(C)OC(=O)N1CCC[C@H](c2noc(-c3ccc[nH]3)n2)C1.Cl>>Cl.c1c[nH]c(-c2nc([C@H]3CCCNC3)no2)c1,,Cl,,ClCCl,,test
US04962115,CCOC(=O)N1CCC(OC)(OC)C(OC)C1>>COC1CNCCC1(OC)OC,,CC(C)O,,[K+].[OH-],,test
US08586604B2,CC(C)(F)C(=O)O.NCc1ccc(Cl)c(Nc2nc3cc(C(=O)N[C@@H]4CC[C@@H](C(F)(F)F)CC4)c(OCC(F)F)nc3[nH]2)c1Cl>>CC(C)(F)C(=O)NCc1ccc(Cl)c(Nc2nc3cc(C(=O)N[C@@H]4CC[C@@H](C(F)(F)F)CC4)c(OCC(F)F)nc3[nH]2)c1Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20110257100A1,O=C1COCCN1Cc1ccc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)nc1>>Nc1ccc(Oc2ccnc3cc(-c4ccc(CN5CCOCC5=O)cn4)sc23)c(F)c1,[Zn],CO,O,[Cl-].[NH4+],,test
US20050038107A1,COc1ccc(OC)c(CC(=O)c2ccc(OC)c(F)c2)c1>>Oc1ccc2oc(-c3ccc(O)c(F)c3)cc2c1,,CCOC(C)=O,,Cl,,test
US20160096839A1,C[C@@H]1C=CC[C@H](NC(=O)OC(C)(C)C)c2cncc(c2)-c2c(cnn2C(F)F)NC1=O>>C[C@@H]1CCC[C@H](NC(=O)OC(C)(C)C)c2cncc(c2)-c2c(cnn2C(F)F)NC1=O,O=[Pt]=O,CCO,,,,test
US20050009895A1,COC(=O)CBr.COc1cc(C(=O)NCc2ccc(-c3noc(C)n3)cc2NCCc2ccccc2)cc(OC)c1C>>COc1cc(C(=O)NCc2ccc(-c3noc(C)n3)cc2N(CCc2ccccc2)CC(=O)O)cc(OC)c1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090082254A1,C#CCOc1ccc(C(=O)OC)cc1>>C#CCOc1ccc(C(=O)O)cc1,,CCO,,O,[Na+].[OH-],test
US20160009744A1,CC(=O)c1csc(C(=O)c2cncnc2N[C@@H]2C[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)C2)c1>>CC(=O)c1csc(C(=O)c2cncnc2N[C@@H]2C[C@H](CO)[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)C2)c1,,CCO,,Cl,,test
US20120015052A1,BrBr.COC(=O)c1ccc2cnn(-c3ccc(C)cc3)c2c1>>COC(=O)c1ccc2c(Br)nn(-c3ccc(C)cc3)c2c1,,CC#N,,,,test
US20080039437A1,CCOC(=O)c1cc(C#N)c(=O)[nH]c1C(F)F.O=C(Cl)C(=O)Cl>>CCOC(=O)c1cc(C#N)c(Cl)nc1C(F)F,,ClCCl,,CN(C)C=O,,test
US05248793,CC(C)(C)OC(=O)C[C@H]1C[C@@H](CO)OC(C)(C)O1.O=S(=O)(Cl)c1cc(Cl)ccc1Cl>>CC(C)(C)OC(=O)C[C@H]1C[C@@H](COS(=O)(=O)c2cc(Cl)ccc2Cl)OC(C)(C)O1,,ClCCl,,CCN(CC)CC,O,test
US06627630B1,COc1cn2nc(Cl)ccc2n1.OCCCN1CCN(C(c2ccccc2)c2ccccc2)CC1>>COc1cn2nc(OCCCN3CCN(C(c4ccccc4)c4ccccc4)CC3)ccc2n1,,CN(C)C=O,,[H-].[Na+],,test
US20020103226A1,COc1ccc(O)cc1.N#CCCl>>COc1ccc(OCC#N)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050137214A1,CC(C)(C)OC(=O)N1CCN(c2ccc(N)nc2)CC1.Cc1cc(=O)n(C2CCCC2)c2nc(S(C)=O)ncc12>>Cc1cc(=O)n(C2CCCC2)c2nc(Nc3ccc(C4CNCCN4C(=O)OC(C)(C)C)cn3)ncc12,,Cc1ccccc1,,,,test
US20130096120A1,CI.SC12CC3CC(C1)CC(Cn1cccn1)(C3)C2>>CSC12CC3CC(CC(Cn4cccn4)(C3)C1)C2,,CO,,C[O-].[Na+],,test
US20120214794A1,CC(C)(C)OC(=O)NCC#Cc1ccc(Cl)cc1.CCCC[SnH](CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)/C(=C/CNC(=O)OC(C)(C)C)c1ccc(Cl)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,,,,test
US04456757,CC(=O)NC(C)CN.O=S(=O)(Cl)c1cccc2cnccc12>>CC(=O)NC(C)CNS(=O)(=O)c1cccc2cnccc12,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20120196864A1,BrCc1ccccc1.CCN1C(=N)/C(=C/c2ccc(OCc3ccc(C(F)(F)F)cc3C(F)(F)F)c(OC)c2)NC1=O>>CCN1C(=N)/C(=C/c2ccc(OCc3ccc(C(F)(F)F)cc3C(F)(F)F)c(OC)c2)N(Cc2ccccc2)C1=O,,C1CCOC1,CCOC(C)=O,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US20150291595A1,COc1cc(B(O)O)cc(C(F)(F)F)n1.Cc1ccn2nc([C@H](C)Nc3ncnc(N)c3Br)n(-c3ccccc3)c(=O)c12>>COc1cc(-c2c(N)ncnc2N[C@@H](C)c2nn3ccc(C)c3c(=O)n2-c2ccccc2)cc(C(F)(F)F)n1,,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080262055A1,Cc1snc2c1C(=O)N=C(NC(=O)OC(C)(C)C)NCc1cc(Cl)c(c(Cl)c1)NC(=O)CN(C(=O)OC(C)(C)C)CCCC=CCOc1ccc-2cc1>>Cc1snc2c1C(=O)N=C(N)NCc1cc(Cl)c(c(Cl)c1)NC(=O)CNCCCCCCOc1ccc-2cc1,[Pd],CO,,[H][H],,test
US04144235,ClP(Cl)(Cl)(Cl)Cl.O=C1Nc2cc(Br)ccc2Oc2cscc21>>ClC1=Nc2cc(Br)ccc2Oc2cscc21,,Cc1ccccc1,,,,test
US20070208001A1,CCOC(=O)C1CCC(O)CC1.Oc1ccc(Br)cc1>>CCOC(=O)C1CCC(Oc2ccc(Br)cc2)CC1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04476137,CC(C)(C#N)CNN.Clc1nc2ccccc2o1>>CC(C)(C#N)CN(N)c1nc2ccccc2o1,,C1COCCO1,,CCN(CC)CC,,test
US06015868,CCCc1cc2ccccc2[cH-]1.C[SiH](C)N(Cl)C(C)(C)C>>CCCC1=Cc2ccccc2C1[Si](C)(C)NC(C)(C)C,,C1CCOC1,,[Li],,test
US20020032184A1,CCc1nn(CCN)c(CC)c1Cc1cc(Cl)cc(Cl)c1.Cn1cnc(S(=O)(=O)Cl)c1>>CCc1nn(CCNS(=O)(=O)c2cn(C)cn2)c(CC)c1Cc1cc(Cl)cc(Cl)c1,,CN(C)C=O,,CCN(CC)CC,,test
US20120309739A1,CCI.CSc1nc2oc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)c2c(=O)[nH]1>>CCn1c(SC)nc2oc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)c2c1=O,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130150362A1,C=C1CCC(c2cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n3ncc(-c4ccc(-c5ccccc5)nc4)c3n2)CC1.O=C(OO)c1cccc(Cl)c1>>C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)c1cc(C2CCC3(CC2)CO3)nc2c(-c3ccc(-c4ccccc4)nc3)cnn12,,ClCCl,,,,test
US20150111885A1,CCc1ccc(S(C)(=O)=O)cc1[N+](=O)[O-]>>CCc1ccc(S(C)(=O)=O)cc1N,[Pd],CO,,CCOC(C)=O,,test
US04806549,CCCC(=O)c1cnc2c(C)cccc2c1Cl.COc1ccc(C)cc1N>>CCCC(=O)c1cnc2c(C)cccc2c1Nc1cc(C)ccc1OC,,C1COCCO1,,,,test
US05578593,CC(C)(C)OC(=O)N1CCC2(CC1)CC(N)c1ccccc12.CN=C=O>>CNC(=O)NC1CC2(CCN(C(=O)OC(C)(C)C)CC2)c2ccccc21,,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US20140200197A1,CC(C)(C)OC(=O)N[C@H](C(=O)Nc1cccc(F)c1OC[C@@H]1CN(C(=O)OC(C)(C)C)[C@H](CO[Si](C)(C)C(C)(C)C)CO1)C(c1ccc(F)cc1)c1ccc(F)cc1>>CC(C)(C)OC(=O)N[C@H](C(=O)Nc1cccc(F)c1OC[C@@H]1CN(C(=O)OC(C)(C)C)[C@H](CO)CO1)C(c1ccc(F)cc1)c1ccc(F)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06169086A,N#Cc1cc(F)cc(N2CCNCC2)c1.O=C(Cl)OCC(Cl)(Cl)Cl>>N#Cc1cc(F)cc(N2CCN(C(=O)OCC(Cl)(Cl)Cl)CC2)c1,,ClCCl,,CCN(CC)CC,Cl,test
US20140288068A1,Cc1nccc2c1[nH]c1cc(OC(F)(F)CBr)ccc12>>Cc1nccc2c1[nH]c1cc(OC(C)(F)F)ccc12,[Pd],CCO,,,,test
US20130317074A1,COc1cc([N+](=O)[O-])c(O)cc1C.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1cc([N+](=O)[O-])c(OS(=O)(=O)c2ccc(C)cc2)cc1C,,ClCCl,,CCN(CC)CC,O,test
US05312820,CC(C)(C)NS(=O)(=O)c1ccccc1Br.Cc1ccc([Sn](C)(C)C)cc1>>Cc1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,,,test
US20090202480A1,BrCc1ccccc1.CC(C)(C)OC(=O)NS(=O)(=O)C1CC1.O>>CC(C)(C)OC(=O)NS(=O)(=O)C1(OCc2ccccc2)CC1,,C1CCOC1,CCOC(C)=O,[Li]CCCC,,test
US20120028961A1,BrP(Br)Br.OCc1ccc2ncsc2c1>>BrCc1ccc2ncsc2c1,,CCOCC,,,,test
US05739129,COc1ccc(N(C(=O)CN)C(C)C)cc1.O=[N+]([O-])c1cc(F)ccc1F>>COc1ccc(N(C(=O)CNc2ccc(F)cc2[N+](=O)[O-])C(C)C)cc1,,CCO,O,,,test
US20100016319A1,CN1CCCC1CCN.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2Oc2ccnc(Cl)n2)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2Oc2ccnc(NCCC3CCCN3C)n2)cc1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US04820834,CN1C(=O)C(N)N=C(c2ccccc2)c2ccccc21.O=C=Nc1ccc(F)cc1>>CN1C(=O)C(NC(=O)Nc2ccc(F)cc2)N=C(c2ccccc2)c2ccccc21,,C1CCOC1,,,,test
US20140005168A1,CC(C)(C)OC(=O)N1CCN(c2nc(I)ccc2Br)CC(O)C1.FC(F)(F)Cn1cc(-c2cc3[nH]ncc3cn2)cn1>>CC(C)(C)OC(=O)N1CCN(c2nc(-n3ncc4cnc(-c5cnn(CC(F)(F)F)c5)cc43)ccc2Br)CC(O)C1,[Cu]I,C1COCCO1,,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US20150087699A1,CC(O)c1oc2cccc(F)c2c(=O)c1-c1cccc(F)c1.CS(=O)(=O)Cl>>C[C@@H](OS(C)(=O)=O)c1oc2cccc(F)c2c(=O)c1-c1cccc(F)c1,,ClCCl,,CCN(CC)CC,,test
US20110046147A1,COc1cccc(-c2nnc(-c3cccc(OC)c3)o2)c1>>Oc1cccc(-c2nnc(-c3cccc(O)c3)o2)c1,,CCCCCC,CCOC(C)=O,,,test
US20090047246A1,C[Si](C)(C)N=[N+]=[N-].N#CCc1c(-c2ccccc2)n(Cc2csc3ccc(Cl)cc23)c2ccccc12>>Clc1ccc2scc(Cn3c(-c4ccccc4)c(Cc4nnn[nH]4)c4ccccc43)c2c1,,Cc1ccccc1,,Cl,,test
US06723722B1,NOP(=O)(c1ccccc1)c1ccccc1.O=C1CN(C(=O)OCc2ccccc2)CCN1>>NN1CCN(C(=O)OCc2ccccc2)CC1=O,,CN(C)C=O,,[H-].[Na+],,test
US04978665,CCCOc1cc(CN)ccc1OC.CCn1nc(Cl)c(Cl)c(Cl)c1=O>>CCCOc1cc(CNc2c(Cl)nn(CC)c(=O)c2Cl)ccc1OC,,CCO,,,,test
US20050171180A1,CCC(CC)C(N=[N+]=[N-])c1nccn1Cc1ccccc1>>CCC(CC)C(N)c1nccn1Cc1ccccc1,[Pd],CO,,,,test
US04857558,CC(=O)CCCCl.CC(C)(C)c1cc(S)cc(C(C)(C)C)c1O>>CC(=O)CCCSc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1,,CCOCC,,CCN(CC)CC,,test
US20080300231A1,CC(C)(C)OC(=O)NCCN.CC(C)(C)OC(=O)N[C@@H](CCCOS(C)(=O)=O)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCNCCC[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US07795448B2,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(C(=O)CBr)cc1)CN1C(=O)c2ccccc2C1=O.CC(O)c1cccnc1N>>CC(O)c1cccn2cc(-c3ccc(C[C@@H](CN4C(=O)c5ccccc5C4=O)NC(=O)OC(C)(C)C)cc3)nc12,,CC(C)O,,O=C([O-])O.[Na+],,test
US20080139595A1,O=C(Nc1ccc(Oc2ccnc3[nH]cc(Cl)c23)c(F)c1)C(F)(F)F>>Nc1ccc(Oc2ccnc3[nH]cc(Cl)c23)c(F)c1,,C1CCOC1,,[Na+].[OH-],,test
US03941793,CCCCc1ccc2nc(C(=O)OCC)cc(O)c2c1.O=P(Cl)(Cl)Cl>>CCCCc1ccc2nc(C(=O)OCC)cc(Cl)c2c1,,CCO,,O,O=C([O-])[O-].[Na+].[Na+],test
US04410518,CCOP(=S)(NC(C)C)OCC.CNC(=O)ON=C(SC)C(=O)N(C)C.O=S(Cl)Cl>>CCOP(=S)(OCC)N(C(C)C)S(=O)CNC(=O)ON=C(SC)C(=O)N(C)C,,c1ccncc1,,,,test
US20070281933A1,NC(=O)c1cc(-c2ccccc2)cc2c(C3CCN(S(=O)(=O)CCCCl)CC3)n[nH]c12.OCCC1CNCCN1>>NC(=O)c1cc(-c2ccccc2)cc2c(C3CCN(S(=O)(=O)CCCN4CCNC(CCO)C4)CC3)n[nH]c12,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US20100331295A1,FC(F)(F)c1cc(-c2cccs2)n(-c2ccccc2Cl)n1.O=S(=O)(O)Cl>>O=S(=O)(O)c1ccc(-c2cc(C(F)(F)F)nn2-c2ccccc2Cl)s1,,ClCCl,,O=S(=O)([O-])[O-].[Na+].[Na+],,test
US04981992,COC(=O)C(CNC(=O)CCl)C(C)=O>>COC(=O)[C@@H](CNC(=O)CCl)[C@@H](C)O,,ClCCl,,,,test
US20140243239A1,CC(C)(C)OC(=O)NCCCN1CCC2(CC1)CCN(c1ncnc3[nH]cc(Cl)c13)C2>>NCCCN1CCC2(CC1)CCN(c1ncnc3[nH]cc(Cl)c13)C2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040019065A1,CCC(=O)OC(=O)CC.CO[C@H]1CCN(C(=O)c2cc3nccc(Oc4ccc5[nH]c(C)cc5c4)c3s2)C1>>CCC(=O)n1c(C)cc2cc(Oc3ccnc4cc(C(=O)N5CC[C@H](OC)C5)sc34)ccc21,,C1CCOC1,,[H-].[Na+],,test
US20100029621A1,O=Cc1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1>>OCc1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1,,CO,,[BH4-].[Na+],,test
US20090192203A1,NC(=S)COC(=O)c1ccccc1.O=C(CBr)c1ccc(-c2ccccc2)cc1>>OCc1nc(-c2ccc(-c3ccccc3)cc2)cs1,,CO,,O,O=S(=O)(O)O,test
US20100216788A1,Cc1cc(N)ccc1Oc1cccc(OCC2CC2)c1.O=C(OCCn1ccc2ncnc(Cl)c21)c1ccccc1>>Cc1cc(Nc2ncnc3ccn(CCO)c23)ccc1Oc1cccc(OCC2CC2)c1,,CC(C)O,,[Na+].[OH-],,test
US20130005707A1,CC(C)(C)[Si](C)(C)OCCN.COC(=O)c1ccc([N+](=O)[O-])cc1CBr>>CC(C)(C)[Si](C)(C)OCCN1Cc2cc([N+](=O)[O-])ccc2C1=O,,CO,,,,test
US20160145245A1,CCN(CCOC)C[C@@H](NC)c1ccccc1.O=C(O)Cc1ccc(Cl)c(Cl)c1>>CCN(CCOC)C[C@H](c1ccccc1)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1,,CC#N,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20100160387A1,COc1ccc(CC(=O)O)cc1OC.ClI>>COc1cc(I)c(CC(=O)O)cc1OC,,CC(=O)O,,O=S([O-])O.[Na+],,test
US20130274227A1,N#Cc1c(Nc2cccc(Cl)c2)n[nH]c1N.O=Cc1ccc(C(F)(F)F)cc1>>N#Cc1c(Nc2cccc(Cl)c2)n[nH]c1N=Cc1ccc(C(F)(F)F)cc1,C1CCNCC1,CCO,,,,test
US20060074084A1,CCCNC(=O)c1[nH]c2ccc(N)cc2c1-c1ccccc1.O=S(=O)(Cl)c1ccc(OC(F)(F)F)cc1>>CCCNC(=O)c1[nH]c2ccc(NS(=O)(=O)c3ccc(OC(F)(F)F)cc3)cc2c1-c1ccccc1,,CCCCCC,CCOC(C)=O,,,test
US20160075906A1,C=C(C)C(=O)OCCO.N#CBr>>C=C(C)C(=O)OCCOC#N,,C1CCOC1,,[Li]CCCC,,test
US04640920,Clc1ccc2c(Cl)ncnc2c1.Nc1ccc(S(=O)(=O)O)cc1>>O=S(=O)(O)c1ccc(Nc2ncnc3cc(Cl)ccc23)cc1,,CCO,,,,test
US20130029990A1,COCC(=O)Nc1cc(Oc2ccc([N+](=O)[O-])c3[nH]ncc23)ccn1>>COCC(=O)Nc1cc(Oc2ccc(N)c3[nH]ncc23)ccn1,[Pt],C1CCOC1,CN(C)C=O,[H][H],,test
US20080194535A1,C=CCOC1Cc2ccc(OC)cc2C1N=[N+]=[N-]>>C=CCO[C@@H]1Cc2ccc(OC)cc2[C@H]1N,,C1CCOC1,,[H-].[Na+],,test
US20090227588A1,N#Cc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)cc1>>NCc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)cc1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040248983A1,COc1cc(CC(=O)Oc2c(F)c(F)c(F)c(F)c2F)ccc1O.Nc1cccc(C2=CCCCC2)c1>>COc1cc(CC(=O)Nc2cccc(C3=CCCCC3)c2)ccc1O,,CCOC(C)=O,,,,test
US20090264445A1,CC1(C)OC[C@@H](Cn2ccc(N)n2)O1.O=C(O)C(CC1(F)CCCC1)N1CC(Oc2c(F)cccc2F)=CC1=O>>CC1(C)OC[C@@H](Cn2ccc(NC(=O)C(CC3(F)CCCC3)N3CC(Oc4c(F)cccc4F)=CC3=O)n2)O1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US05182295,CO.O=C(O)CC1(c2ccccc2)CC=C2C=CC=C2O1>>COC(=O)CC1(c2ccccc2)CC=C2C=CC=C2O1,,O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20060252790A1,CC(C)CC(=O)Cl.CCn1ncc2c(NC3CCOCC3)c(-c3nc(CC4CCNCC4)no3)cnc21>>CCn1ncc2c(NC3CCOCC3)c(-c3nc(CC4CCN(C(=O)CC(C)C)CC4)no3)cnc21,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,Cl,test
US20040204409A1,COC(=O)c1ccc2onc(O)c2c1.OCc1ccccc1>>COC(=O)c1ccc2onc(OCc3ccccc3)c2c1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110245289A1,CCc1nc2c(N)nc3ccccc3c2n1CCCCN(C(=O)OC(C)(C)C)C1CCOCC1>>CCc1nc2c(N)nc3ccccc3c2n1CCCCNC1CCOCC1,,O=C(O)C(F)(F)F,,,,test
US20120302755A1,COCCl.O=[N+]([O-])c1cc(Br)cnc1-c1ccc(O)cc1>>COCOc1ccc(-c2ncc(Br)cc2[N+](=O)[O-])cc1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20070203129A1,CNC(C)=O.Cc1c(C(=O)NN)cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n1-c1cccc(C(F)(F)F)c1>>Cc1nnc(-c2cc(C(=O)NCc3ccc(S(C)(=O)=O)cc3)c(=O)n(-c3cccc(C(F)(F)F)c3)c2C)n1C,,ClC(Cl)Cl,c1ccncc1,O=P(Cl)(Cl)Cl,,test
US20100249123A1,COc1ccc(C(=O)Nc2cccc(C3(CN)CCCC3)c2)cc1OC.Cn1nc(C(=O)O)c2ccccc21>>COc1ccc(C(=O)Nc2cccc(C3(CNC(=O)c4nn(C)c5ccccc45)CCCC3)c2)cc1OC,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20080132548A1,CC(C)c1ccc(-c2nn[nH]n2)cc1.COC(=O)C(C)(C)CO>>COC(=O)C(C)(C)Cn1nnc(-c2ccc(C(C)C)cc2)n1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04849422,Brc1nccs1.OCC(O)CN1CCNCC1>>OCC(O)CN1CCN(c2nccs2)CC1,,C1COCCO1,,,,test
US20100004280A1,CN(C)C=O.CN(C)S(=O)(=O)n1cnc(CC(C)(C)C)c1>>CN(C)S(=O)(=O)n1cc(CC(C)(C)C)nc1C=O,,C1CCOC1,,[Li]CCCC,,test
US20100168161A1,Cc1cc(CC(N)=O)ccc1OCc1ccccc1>>Cc1cc(CC(N)=O)ccc1O,[Pd],CC(=O)O,,,,test
US20100048606A1,BrCc1ccccc1.COCOCc1cc(OC)nc(-c2cncc(CO)c2)c1>>COCOCc1cc(OC)nc(-c2cc(CO)c[n+](Cc3ccccc3)c2)c1.[Br-],,CC#N,,,,test
US20140187553A1,CC(C)(C)OC(=O)n1cc(-c2cnc3ccccc3c2)c2cc(Br)ccc21.CCCC[Sn](CCCC)(CCCC)c1cnc(NC(=O)OC(C)(C)C)s1>>Nc1ncc(-c2ccc3[nH]cc(-c4cnc5ccccc5c4)c3c2)s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,[Cl-].[Li+],,test
US20140163025A1,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5ccc(-c6ccnn6C)cc5F)ccc(F)c43)ccc21>>Cn1nccc1-c1ccc(Oc2ccc(F)c3c2CC[C@H]3Oc2ccc3c(c2)OC[C@H]3CC(=O)O)c(F)c1,,CCO,,[K+].[OH-],,test
US05541213,O=C1c2ccccc2C(=O)N1C(Cc1ccccn1)c1cccc(Cl)c1>>NC(Cc1ccccn1)c1cccc(Cl)c1,,CCO,,NN,O,test
US05573949,CCOC(=O)Cl.COc1ccc2c(c1)C[C@H](C(=O)O)CC2.[N-]=[N+]=[N-]>>COc1ccc2c(c1)C[C@H](N)CC2.Cl,,CC(C)=O,O,CCN(CC)CC,,test
US20020002183A1,N#Cc1ccccc1-c1ccc(C(=O)Nc2ccccc2C(=O)Nc2ccc(Cl)cn2)cc1.NO>>O=C(Nc1ccccc1C(=O)Nc1ccc(Cl)cn1)c1ccc(-c2ccccc2C=NNO)cc1,,CCO,,CCN(CC)CC,Cl,test
US20100152187A1,CCN(CC)Cc1nc(N)sc1C(=O)NCc1ccccc1.O=C(O)c1ccc(Cc2ccccc2)cc1>>CCN(CC)Cc1nc(NC(=O)c2ccc(Cc3ccccc3)cc2)sc1C(=O)NCc1ccccc1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030225266A1,CC(CNS(=O)(=O)C(C)C)Oc1ccc(Br)cc1.O=Cc1ccccc1B(O)O>>CC(CNS(=O)(=O)C(C)C)Oc1ccc(-c2ccccc2C=O)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US06576656B1,O=C1CCC(=O)N1I.O=C1Nc2cccc(C(F)(F)F)c2C1=O>>O=C1Nc2c(I)ccc(C(F)(F)F)c2C1=O,,O=S(=O)(O)O,,,,test
US20050014787A1,CS(=O)(=O)Cl.O=C1OCCN1c1ccc(CCO)cc1>>CS(=O)(=O)OCCc1ccc(N2CCOC2=O)cc1,,ClCCl,,,,test
US20040248913A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.COCOc1c(I)cc(C(C)C)nc1C(C)C>>C=C(OCC)c1cc(C(C)C)nc(C(C)C)c1OCOC,,CN(C)C=O,,,,test
US20050054627A1,CC(C)(C)C(=N)N.O=C/C(Br)=C(/Br)C(=O)O>>CC(C)(C)c1ncc(Br)c(C(=O)O)n1,,CCO,Cl,C,C[O-].[Na+],test
US20080167371A1,CC(C)CCNC(=O)c1ccc(Br)c(F)c1>>CC(C)CCNCc1ccc(Br)c(F)c1,,C1CCOC1,,B,Cl,test
US05489591,Clc1nc(N2CCOCC2)nc(N2CCOCC2)n1.c1c[nH]cn1>>c1cn(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)cn1,,CN(C)C=O,,[Na+].[OH-],,test
US20080260651A1,CC(=O)OCC(OC(C)=O)C(=O)O.O=S(Cl)Cl>>CC(=O)OCC(OC(C)=O)C(=O)Cl,,CN(C)C=O,,,,test
US20150250911A1,CC(C)c1cccc(C(C)CC=O)c1>>CC(C)C1CCCC(C(C)CCO)C1,[Ru],,,,,test
US04620000,CC(=O)O.Cc1ccc(N)cc1C>>CC(=O)Nc1ccc(C)c(C)c1,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20120329785A1,COc1cc(N)cc(OC)c1OC.COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccccc23)cc1>>COc1cc(Nc2nc3ccccc3c3c[nH]nc23)cc(OC)c1OC,C1COCCO1,CO,,Cl,,test
US20130059849A1,CCOC(=O)C(=O)CC(=O)C1CC1.Cc1cc(N)n(-c2ccncc2)n1>>CCOC(=O)c1cc(C2CC2)nc2c1c(C)nn2-c1ccncc1,,CC(=O)O,,c1ccccc1,,test
US20100016315A1,ClCc1cc(Cl)cc(Cl)c1.NC(=O)c1cccnc1N>>Cl.N=c1c(C(N)=O)cccn1Cc1cc(Cl)cc(Cl)c1,,CCOC(C)=O,CN(C)C=O,,,test
US20050059786A1,CC(=O)c1cccc(C(C)=Nc2ccccc2C(C)(C)C)n1.Cc1cc(C)cc(N)c1>>CC(=Nc1cc(C)cc(C)c1)c1cccc(C(C)=Nc2ccccc2C(C)(C)C)n1,,Cc1ccccc1,,,,test
US20120264923A1,CC(=CCCOS(=O)(=O)c1ccc(C)cc1)CCCC(C)CCCC(C)C.OCC(O)CO>>CC(=CCCOCC(O)CO)CCCC(C)CCCC(C)C,,CN(C)C=O,,O,[H-].[Na+],test
US04607006,CC(=O)NN.CCn1c2ccccc2c2cc(N=C=S)ccc21>>CCn1c2ccccc2c2cc(NC(=S)NNC(C)=O)ccc21,,C1CCOC1,,CO,,test
US20120225863A1,CC(C)(C)N.CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1ccc2[nH]ncc2c1>>CC(C)N(C)c1nc2cc(C(=O)NC(C)(C)C)ccc2nc1-c1ccc2[nH]ncc2c1,,ClCCl,O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US20030166697A1,COC(=O)C(C)(C)OCCCCCCCC(=O)CCl.NC(=S)c1ccccc1>>COC(=O)C(C)(C)OCCCCCCCc1csc(-c2ccccc2)n1,,CCOC(C)=O,,,,test
US20060014768A1,CI.Cn1c(=O)nc(S)c2c(=O)n(-c3ccccc3)c(=O)n(-c3ccccc3)c21>>CSc1nc(=O)n(C)c2c1c(=O)n(-c1ccccc1)c(=O)n2-c1ccccc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20160060273A1,CCOC(=O)C1(CC)CCN(C2=NOC3(C2)CN(Cc2cc(OCC)c(-c4ccc(F)c(F)c4)c(OCC)c2)C3)CC1>>CCOc1cc(CN2CC3(CC(N4CCC(CC)(C(=O)O)CC4)=NO3)C2)cc(OCC)c1-c1ccc(F)c(F)c1,,CO,,[Na+].[OH-],,test
US20070123557A1,CI.O=C(O)C(O)(c1ccccc1)C1CCCC1>>COC(=O)C(O)(c1ccccc1)C1CCCC1,,CN(C)C=O,ClCCl,O,O=C([O-])[O-].[K+].[K+],test
US20050261333A1,COC1CCC(OC)O1.Nc1c(Cl)cnc2nc(-c3ccc(OCCN4CCOCC4)cc3)[nH]c12>>Clc1cnc2nc(-c3ccc(OCCN4CCOCC4)cc3)[nH]c2c1-n1cccc1,,CC(=O)O,,,,test
US20090149454A1,COc1cc2nccc(Cl)c2cc1OCc1ccccc1.Oc1ccc2c(c1)OCCN2>>COc1cc2nccc(Oc3ccc4c(c3)OCCN4)c2cc1OCc1ccccc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20130217699A1,COC(=O)c1sc(C(=O)CC(O)(c2cc(Cl)c(F)c(Cl)c2)C(F)(F)F)c2c1CCC2>>COC(=O)c1sc(C(=O)C=C(c2cc(Cl)c(F)c(Cl)c2)C(F)(F)F)c2c1CCC2,,ClCCl,,O=S(Cl)Cl,c1ccncc1,test
US04795815,C=CCOC(=O)C1=C(C(=O)OCc2ccccc2)CN2CC(NC(=O)OC(C)(C)C)C(=O)N12.Cl>>C=CCOC(=O)C1=C(C(=O)OCc2ccccc2)CN2CC(N)C(=O)N12.Cl,,CC(=O)O,,Cl,,test
US04665073,CCOC(=O)CCCSc1nccc(NC(=S)NCC(F)(F)F)n1.N>>CCOC(=O)CCCSc1nccc(NC(N)=NCC(F)(F)F)n1,,CN(C)C=O,,,,test
US20050143452A1,[N-]=[N+]=NCC1Cc2cccc(-c3ccc(F)cc3F)c2O1>>NCC1Cc2cccc(-c3ccc(F)cc3F)c2O1,[Pd],,,,,test
US20020028823A1,CC(=O)O[C@H](C)CCCCn1c(=O)c2c(ncn2C)n(CCCCCCNC(=O)OC(C)(C)C)c1=O>>CC(=O)O[C@H](C)CCCCn1c(=O)c2c(ncn2C)n(CCCCCCN)c1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080269196A1,CC(C)CN.N#Cc1ccc(C=O)cc1>>CC(C)CNCc1ccc(C#N)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20120225854A1,CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)C[C@@H]2COS(C)(=O)=O)cc1)C(F)(F)F.CC1CNC(=O)CN1>>CC1CNC(=O)CN1C[C@H]1CN(S(=O)(=O)c2cccs2)CCN1c1ccc(C(C)(O)C(F)(F)F)cc1,,CC#N,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20130079383A1,CCCCCCCCCCCCO.CS(=O)(=O)Cl>>CCCCCCCCCCCCOS(C)(=O)=O,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20120214803A1,Nc1cc(C(F)(F)F)ccc1S(=O)(=O)Nc1ccc(F)c2cccnc12>>O=S1(=O)Nc2c(cc(F)c3cccnc23)-c2cc(C(F)(F)F)ccc21,,CC(=O)O,,CC(C)(C)ON=O,,test
US20100197609A1,CCNC.N#Cc1c(Cl)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1ccc(OCCO)cc1>>CCN(C)c1nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c(-c2ccc(OCCO)cc2)c1C#N,,C1CCOC1,,O,,test
US20100125081A1,O=C([O-])C(F)(F)Cl.OCCc1cc(Br)ccc1O>>OCCc1cc(Br)ccc1OC(F)F,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20120035214A1,CC(C)(C)OC(=O)N1CC[C@](O)(c2ccc(F)c(F)c2)[C@@H](C=O)C1.CO>>C#C[C@H]1CN(C(=O)OC(C)(C)C)CC[C@]1(O)c1ccc(F)c(F)c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US05116844,CC(c1ccncn1)C(O)(Cn1cncn1)c1ccc(F)cc1F.O=C(OO)c1cccc(Cl)c1>>CC(c1cc[n+]([O-])cn1)C(O)(Cn1cncn1)c1ccc(F)cc1F,,ClCCl,,,,test
US20080275043A1,Cc1ccc(Br)cc1Cl.NC(=O)CCC(=O)NBr>>Clc1cc(Br)ccc1CBr,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20140309245A1,CC(C)(C)OC(=O)N1CCC(CNC(=O)OCc2ccccc2)(C(=O)Nc2ccccc2)C1>>CC(C)(C)OC(=O)N1CCC(CN)(C(=O)Nc2ccccc2)C1,[Pd],CO,ClCCl,O=C[O-].[NH4+],,test
US20080027112A1,COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc2c1OC/C=C\CO[Si](C)(C)C(C)(C)C>>COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc2c1OC/C=C\CO,,O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05034370,C=O.Cc1ccccc1.O=C(O)c1ccccc1O>>Cc1ccccc1C=O.O=C(O)c1ccccc1O,,CC(=O)O,,O=S(=O)(O)O,,test
US20140323418A1,CC(C)(C)[Si](C)(C)OCCBr.NC(=O)c1cnc(N[C@@H]2CCCC[C@@H]2N)nc1Nc1cccc(-n2nccn2)c1.NC(=O)c1cnc(N[C@H]2CCCC[C@H]2N)nc1Nc1cccc(-n2nccn2)c1>>CC(C)(C)[Si](C)(C)OCCN[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2cccc(-n3nccn3)c2)n1.NC(=O)c1cnc(N[C@@H]2CCCC[C@@H]2N)nc1Nc1cccc(-n2nccn2)c1,,CCOC(C)=O,CN1CCCC1=O,CCN(C(C)C)C(C)C,,test
US05668138,CC(C)(Oc1ccccc1)C(=O)Cl.c1ccc(CN2CCNCC2)cc1>>CC(C)(Oc1ccccc1)C(=O)N1CCN(Cc2ccccc2)CC1,,ClCCl,,,,test
US06462229B1,NCCC[C@](N)(C(=O)O)C(F)F>>NCCC[C@](N)(C(=O)O)C(F)F,,CO,,Cl,O,test
US20050239827A1,CC(=O)Nc1ccc(Nc2nc(N3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](NC(=O)OC(C)(C)C)C3)nc(N3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](NC(=O)OC(C)(C)C)C3)n2)cc1OCc1ccccc1>>CC(C)(C)OC(=O)N[C@H]1C[C@@H](NC(=O)OC(C)(C)C)CN(c2nc(Nc3ccc(N)c(OCc4ccccc4)c3)nc(N3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](NC(=O)OC(C)(C)C)C3)n2)C1,,C1COCCO1,CO,NN,O,test
US20150322076A1,COC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](C[C@H](C)C(F)(F)F)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)c(OC)c1>>COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](C[C@H](C)C(F)(F)F)[C@@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F,,C1CCOC1,,O,[Na+].[OH-],test
US20090181965A1,COc1cc(NC(N)=S)ccc1-n1cnc(C)c1.O=C1C(Br)CCCC1c1cc(F)cc(F)c1>>COc1cc(Nc2nc3c(s2)CCCC3c2cc(F)cc(F)c2)ccc1-n1cnc(C)c1,,CCO,,,,test
US20080070924A1,Cc1cc(C)cc(O)c1.O=C(Cl)C(Cl)c1ccccc1>>Cc1cc(C)cc(OC(=O)C(Cl)c2ccccc2)c1,,CN(C)C=O,,O,[H-].[Na+],test
US05093353,CCCc1c(OCCCOc2ccccc2)ccc2c1OC(CCC(=O)OC)(CCC(=O)OC)CC2=O>>CCCc1c(OCCCOc2ccccc2)ccc2c1OC(CCC(=O)O)(CCC(=O)O)CC2=O,,O,,[Na+].[OH-],,test
US20100004280A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COC(=O)C(Cc1ccc(Br)cc1)NC(C)=O>>COC(=O)C(Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1)NC(C)=O,,CS(C)=O,O,,,test
US20090186869A1,CCOc1cc2ccccc2cn1.O=C(OO)c1cccc(Cl)c1>>CCOc1cc2ccccc2c[n+]1[O-],,ClCCl,,,,test
US05998442,COc1ccc([Mg]Br)cc1OC.COc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(N(C)C)sc2c1>>COc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(OC)c(OC)c3)sc2c1,,C1CCOC1,,,,test
US04536518,CCOC(=O)C(CC(=O)O)=C(c1ccccc1)c1ccc(F)cc1>>O=C(O)CC=C(c1ccccc1)c1ccc(F)cc1,,CC(=O)O,,Br,,test
US20090163524A1,CC(C)(C)OC(=O)NC1(C(=O)NC(Cc2nccn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1>>NC1(C(=O)NC(Cc2ncc[nH]2)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1,O,CO,,O=C(O)C(F)(F)F,,test
US20080312227A1,CC(C)(C)C(=O)Nc1nc2ncc(Br)cc2c(=O)[nH]1.OB(O)c1ccc(F)cc1>>CC(C)(C)C(=O)Nc1nc2ncc(-c3ccc(F)cc3)cc2c(=O)[nH]1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US20070167507A1,CCOC(=O)c1cn(-c2ccccc2)nc1N.C[C@@H]1CC[C@@H](C(=O)Cl)CC1>>CCOC(=O)c1cn(-c2ccccc2)nc1NC(=O)[C@@H]1CC[C@@H](C)CC1,,ClCCl,,CCN(CC)CC,,test
US20060074111A1,CCCCN(Cc1ccc(OCC(=O)OC)c(C)c1)c1cccc(-c2ccc(C(F)(F)F)cc2)n1>>CCCCN(Cc1ccc(OCC(=O)O)c(C)c1)c1cccc(-c2ccc(C(F)(F)F)cc2)n1,,C1CCOC1,CO,[Na+].[OH-],,test
US20100331320A1,CC(C)(CO)Cn1ccc(Br)cc1=O.C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O>>C[C@@H](c1ccc(-c2ccn(CC(C)(C)CO)c(=O)c2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US05637770,COC(=O)CCCc1ccc(F)cc1NC(C)=O>>CC(=O)Nc1cc(F)cc2c1CCCC2=O,,CO,,Cl,,test
US20150111877A1,CC(C)(C)OC(=O)NC[C@H](O)C(=O)O.CI>>COC(=O)[C@@H](O)CNC(=O)OC(C)(C)C,,CCOC(C)=O,CN(C)C=O,O=C([O-])O.[Na+],,test
US06784181B2,CCN(CC)C(=O)c1ccc(C(c2cccc3cccnc23)N2CCNCC2)cc1.Cc1ccc(CBr)cc1>>CCN(CC)C(=O)c1ccc(C(c2cccc3cccnc23)N2CCN(Cc3ccc(C)cc3)CC2)cc1,,ClCCl,,CCN(CC)CC,,test
US20110281854A1,CCOC(=O)CBr.C[C@@H]1CN(c2ccc(O)c(NC(=O)C(C)(C)C)n2)[C@H](c2ccccc2)CO1>>CCOC(=O)COc1ccc(N2C[C@@H](C)OC[C@H]2c2ccccc2)nc1NC(=O)C(C)(C)C,,CC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20150065468A1,CC1(C)OB(c2ccc(CC(=O)O)cc2)OC1(C)C.COc1cc2ncc(Cl)nc2cc1OC>>COc1cc2ncc(-c3ccc(CC(=O)O)cc3)nc2cc1OC,,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20140336190A1,Cc1cc(C)on1.Cc1noc(C)c1-c1cc(C(=O)c2cccnc2)c2nc(C3CC3)n(C(=O)OC(C)(C)C)c2c1>>Cc1noc(C)c1-c1cc(C(O)(c2cccnc2)c2c(C)noc2C)c2nc(C3CC3)[nH]c2c1,,C1CCOC1,CCOC(C)=O,O,[Li]CCCC,test
US20150344466A1,CCOC(=O)C(=O)CC(=O)COCc1ccccc1.NN>>CCOC(=O)c1cc(COCc2ccccc2)n[nH]1,,CCO,,O,,test
US20140274907A1,C/C=C/C1=CN2C(=O)c3cc(OC)c(OCCCOc4cc5c(cc4OC)C(=O)N4C=C(/C=C/CNC(=O)OCC6c7ccccc7-c7ccccc76)C[C@H]4C(=O)N5COCC[Si](C)(C)C)cc3N(COCC[Si](C)(C)C)C(=O)[C@@H]2C1>>C/C=C/C1=CN2C(=O)c3cc(OC)c(OCCCOc4cc5c(cc4OC)C(=O)N4C=C(/C=C/CN)C[C@H]4C(=O)N5COCC[Si](C)(C)C)cc3N(COCC[Si](C)(C)C)C(=O)[C@@H]2C1,,CN(C)C=O,,C1CCNCC1,,test
US20100041663A1,C[C@@H]1CNCCN1.Cc1c(Cl)nnc(C(=O)c2ccccn2)c1C>>Cc1c(C(=O)c2ccccn2)nnc(N2CCN[C@H](C)C2)c1C,,CN1CCCC1=O,,CCN(CC)CC,,test
US20060161002A1,Clc1ncccn1.NC1CCCc2c1[nH]c1ccc(Br)cc21>>Brc1ccc2[nH]c3c(c2c1)CCCC3Nc1ncccn1,,CCOC(C)=O,CN(C)C=O,,,test
US20150225342A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.CC(C)[Si](Oc1cnc(Cl)nc1)(C(C)C)C(C)C>>C=C(OCC)c1ncc(O[Si](C(C)C)(C(C)C)C(C)C)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20160157491A1,FC(F)(F)Oc1ccc(-n2ncc3c2CCc2cc(Br)ccc2-3)cc1>>FC(F)(F)Oc1ccc(-n2ncc3c4ccc(Br)cc4ccc32)cc1,,Cc1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20120245178A1,Cc1cnc2ccc(C#N)cn12>>Cc1cnc2ccc(CN)cn12,[Ni],CO,,N,,test
US20090042892A1,COc1ccc(C2CCC3(CC2)OCCO3)cc1>>COc1ccc(C2CCC(=O)CC2)cc1,,C1CCOC1,CCOC(C)=O,Cl,,test
US20060111584A1,O=C(F)C(F)(OC(F)(F)C(F)(F)C(F)(F)S(=O)(=O)F)C(F)(F)F.O=C([O-])O.[K+]>>O=C(O[K])C(F)(OC(F)(F)C(F)(F)C(F)(F)S(=O)(=O)F)C(F)(F)F,,COCCOC,,,,test
US20070149600A1,C=CC(=C)O[Si](C)(C)C.COc1ccc(C2=CC(=O)N(C)C2=O)cc1OC>>COc1ccc([C@@]23CCC(=O)C[C@@H]2C(=O)N(C)C3=O)cc1OC,,Cc1ccccc1,,,,test
US20030207877A1,CON(C)C(=O)CNC(=O)OC(C)(C)C.c1ccoc1>>CC(C)(C)OC(=O)NCC(=O)c1ccco1,,C1CCOC1,,[Li]CCCC,,test
US20160152621A1,COc1cc([N+](=O)[O-])ccc1-c1cncn1C(c1ccccc1)(c1ccccc1)c1ccccc1>>COc1cc(N)ccc1-c1cnc[nH]1,[Pd],CO,,,,test
US20010018452A1,CON=C(C(=O)OC)C1=C(C(ON)=C(C)c2cccc(C(F)(F)F)c2)CC(C)=C(C)C1>>CON=C(C(=O)OC)c1cc(C)c(C)cc1C(ON)=C(C)c1cccc(C(F)(F)F)c1,,Cc1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20080280928A1,COc1cc(C)c(-n2cc(C)c3c(OS(=O)(=O)C(F)(F)F)cc(C)nc32)c(C)c1.N#CCC1CCNCC1>>COc1cc(C)c(-n2cc(C)c3c(N4CCC(CC#N)CC4)cc(C)nc32)c(C)c1,,O,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20160090374A1,CC(=O)N[C@H]1CCNC1.COc1ccc2nc(Cl)nc(Cl)c2c1>>COc1ccc2nc(Cl)nc(N3CC[C@H](NC(C)=O)C3)c2c1,,CCO,,,,test
US06414148B1,BrCCC1OCCO1.COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1O>>Fc1cc(Cl)ccc1Nc1ncnc2cc(OCOCCC3OCCO3)ccc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060281778A1,CC1(C2CCC(=O)CC2)CCCC1.CCOC=O>>CC1(C2CCC(=O)C(C=O)C2)CCCC1,,CCOCC,,CCO,[H-].[Na+],test
US20140200311A1,C=CC[Si](CC=C)(CC=C)CCC[Si](O)(CCC[Si](CC=C)(CC=C)CC=C)C(C)(C)C.CCN(CC)CC>>C=CC[Si](CC=C)(CC=C)CCC[Si](CCC[Si](CC=C)(CC=C)CC=C)(OC)C(C)(C)C,,C1CCOC1,,CCOCC,Cl,test
US05495046,CCCN(CCC)CCCCc1cc(Cl)ccc1OCCc1ccccc1.O=C(O)C(=O)O>>CCCN(CCC)CCCCc1cc(Cl)ccc1OCCc1ccccc1.O=C(O)C(=O)O,,CCO,,,,test
US20080058309A1,Nc1ccc(F)cc1.O=C(CCl)Nc1c(Cl)ccc2nc(N3CCOCC3)ccc12>>O=C(CNc1ccc(F)cc1)Nc1c(Cl)ccc2nc(N3CCOCC3)ccc12,,CC#N,,CCN(C(C)C)C(C)C,,test
US03965181,C(#CC1c2ccccc2C=Cc2ccccc21)COC1CCCCO1>>OCC#CC1c2ccccc2C=Cc2ccccc21,,CC(C)=O,,Cl,[NH4+].[OH-],test
US20030055246A1,CC(C)(C)[Si](C)(C)Cl.OCCc1ccncc1>>CC(C)(C)[Si](C)(C)OCCc1ccncc1,,ClCCl,,CCN(CC)CC,,test
US20160194302A1,CC(=O)NC1CCN(C(=O)CCc2nccn2C)CC1.Cl>>CC(=O)NC1CCN(C(=O)CCc2nccn2C)CC1.Cl,,CCOCC,,,,test
US20150018363A1,Cn1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cc21.OCc1ccsc1>>Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4ccsc4)cc3=O)cc21,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20060040999A1,C[N+](=O)[O-].Cc1ccc(C=O)cc1>>Cc1ccc(C(O)C[N+](=O)[O-])cc1,,CCO,,CC(=O)O,[Na+].[OH-],test
US05589474,O=C1NC2=C(C=CC(C(F)(F)F)C2)Sc2ccccc21.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>FC(F)(F)c1ccc2c(c1)NC(=S)c1ccccc1S2,,c1ccncc1,,O,,test
US04764519,Cc1cc(Br)cnc1CCCCN.O=[N+]([O-])c1cc(Cc2cccnc2)cnc1Cl>>Cc1cc(Br)cnc1CCCCNc1ncc(Cc2cccnc2)cc1[N+](=O)[O-],,CCO,,Cl,,test
US20130143860A1,BrCc1ccccc1.c1cc(OCC2CCOCC2)ccn1>>[Br-].c1ccc(C[n+]2ccc(OCC3CCOCC3)cc2)cc1,,C1CCOC1,,,,test
US20120142647A1,CCCN.Nc1nc(Cl)nc(Cl)n1>>CCCNc1nc(N)nc(Cl)n1,,CC(C)=O,,[Na+].[OH-],,test
US20030236292A1,CC(C)(C)Cc1ccccc1.COC(Cl)Cl>>CC(C)(C)Cc1ccc(C=O)cc1,,ClCCl,,Cl[Sn](Cl)(Cl)Cl,,test
US06066641,Nc1c(N=O)c(=O)[nH]c(=O)n1Cc1ccc(Cl)cc1.O=CO>>Nc1c(NC=O)c(=O)[nH]c(=O)n1Cc1ccc(Cl)cc1,[Zn],,,,,test
US20040192623A1,CC[C@H](C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O.Cl>>CC[C@H](C)[C@H](N)C(=O)O.Cl,,CCO,ClCCl,C1CCNCC1,,test
US04454328,CC(C)(C)OC(=O)N[C@H](CO)C(=O)O.CSC(C)(C)C(N)C(C)C>>CSC(C)(C)C(NC(=O)[C@H](N)CO)C(C)C,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,CCOC(=O)Cl,test
US20100240702A1,CCCC(CC(=O)OCC)n1c(=O)n(Cc2ccc(Cl)c3c(C)c(C)n(C)c23)c2ccccc21>>CCCC(CC(=O)O)n1c(=O)n(Cc2ccc(Cl)c3c(C)c(C)n(C)c23)c2ccccc21,,C1CCOC1,O,[Li+].[OH-],,test
US20050107419A1,CC1(C)OC(=O)CC(=O)O1.CCCCCC(=O)O.CN(C)c1ccncc1.ClCCl>>CCOC(=O)CC(=O)CCCC(C)C,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20140187553A1,Cc1ccc(S(=O)(=O)n2cc(-c3cccc(OC(C)C)n3)c3cc(-c4nsc(NC(=O)OC(C)(C)C)n4)ccc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3cccc(OC(C)C)n3)c3cc(-c4nsc(N)n4)ccc32)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140314669A1,COC(=O)CC(NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1ccc(O)cc1.FCCI>>COC(=O)CC(NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1ccc(OCCF)cc1,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110306607A1,O=C(O)c1ccc(F)c(C(F)(F)F)c1.c1ccc2c(c1)OC1(CCNCC1)c1cccn1-2>>O=C(c1ccc(F)c(C(F)(F)F)c1)N1CCC2(CC1)Oc1ccccc1-n1cccc12,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150080549A1,CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O.N#CCBr>>CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OCC#N,,CC#N,,CCN(C(C)C)C(C)C,,test
US20100093702A1,C=Cc1cc2c(N)nc(-c3nc(C)cs3)nc2s1.CC(C)(C)O.CS(N)(=O)=O>>Cc1csc(-c2nc(N)c3cc(C(O)CO)sc3n2)n1,,CC(C)=O,O,O=S([O-])[O-].[Na+].[Na+],,test
US20070254881A1,CCOC(=O)c1cc(-c2nc(Sc3ccccc3)n(C)n2)n(-c2ccc(OC)nc2)n1>>CCOC(=O)c1cc(-c2ncn(C)n2)n(-c2ccc(OC)nc2)n1,[Ni],CCO,,,,test
US20120071461A1,CN(Cc1ccccc1)C1CCC2(CC1)OCCO2>>CN(Cc1ccccc1)C1CCC(=O)CC1,,CO,,Cl,,test
US20110190297A1,NCCNC(=O)C1CCN(c2c(Cl)cncc2Cl)CC1.O=Cc1ccccc1>>O=C(NCCNCc1ccccc1)C1CCN(c2c(Cl)cncc2Cl)CC1,,CO,,[BH3-]C#N.[Na+],,test
US20120232068A1,COCCN.O=S(=O)(Cl)c1cncc(Br)c1>>COCCNS(=O)(=O)c1cncc(Br)c1,,C1CCOC1,,,,test
US20060148858A1,CC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCCO.CCOC(=O)CCc1cc(O)nn1-c1ccccc1>>CC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCCOc1cc(CCC(=O)O)n(-c2ccccc2)n1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US04960776,Cl.O=C(NCCN1CCCCCC1)N1CCN(c2ccccc2)CC1.c1ccc(N2CCNCC2)nc1>>CCN(CC)CCNC(=O)N1CCN(c2ccccn2)CC1.Cl,,Cl,,C1CCOC1,,test
US20120101124A1,[H]/N=C(/NOC(=O)c1ccc(OC(C)C)c(C#N)c1)c1ccc(CCC(=O)OCC)c2ccn(C)c12>>CCOC(=O)CCc1ccc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)c2c1ccn2C,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20070179165A1,CCCC(CCC)n1cc(C#N)c(=O)c2c(Cl)cccc21.Cc1ccc(B(O)O)c(C)c1>>CCCC(CCC)n1cc(C#N)c(=O)c2c(-c3ccc(C)cc3C)cccc21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20150336949A1,Cc1ccc(S(=O)(=O)n2cc(-c3cnn(Cc4cccc(F)c4)c3C)c3cc(-c4ccc(N5CCN(C(=O)OC(C)(C)C)CC5)nc4)cnc32)cc1.Cl>>Cc1ccc(S(=O)(=O)n2cc(-c3cnn(Cc4cccc(F)c4)c3C)c3cc(-c4ccc(N5CCNCC5)nc4)cnc32)cc1.Cl,,CCOCC,,,,test
US20080085880A1,CCC#N.CO[C@H]1CC2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@H]([C@H](C)C[C@@H]2CC[C@H](n3cnnn3)[C@H](OC)C2)CC(=O)[C@H](C)C=C(C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=CC=C1C>>CCC#N.CO[C@H]1CC2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@H]([C@H](C)C[C@@H]2CC[C@H](n3cnnn3)[C@H](OC)C2)CC(=O)[C@H](C)C=C(C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=CC=C1C,,CCC#N,,Cc1ccccc1,,test
US20050192300A1,CC(C)(C)OC(=O)N1CCNCC1.Cc1nc(NC(=O)CCl)sc1-c1ccnc(Nc2cccc([N+](=O)[O-])c2)n1>>Cc1nc(NC(=O)CN2CCN(C(=O)OC(C)(C)C)CC2)sc1-c1ccnc(Nc2cccc([N+](=O)[O-])c2)n1,,CN(C)C=O,,,,test
US20090163512A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CS(=O)COc1ccc(Cl)cc1/C=C1\C(=O)Nc2cc(Cl)ccc21>>CS(=O)COc1ccc(Cl)cc1/C=C1\C(=O)N(C(=O)OC(C)(C)C)c2cc(Cl)ccc21,CN(C)c1ccncc1,ClCCl,,,,test
US20080171789A1,C[C@H](COC(=O)c1ccccc1)OC(=O)[C@H](Cc1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1)NC(=O)OC(C)(C)C.Cl>>C[C@H](COC(=O)c1ccccc1)OC(=O)[C@H](Cc1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1)NC(=O)OC(C)(C)C.Cl,,C1COCCO1,,,,test
US04143047,O=P(Cl)(Cl)Cl.S=c1[nH]cc(-c2ccccc2)o1>>Clc1ncc(-c2ccccc2)o1,,CCN(CC)CC,,,,test
US20090186870A1,COC(=O)c1cc(-c2ncccn2)ccc1Cl.N>>NC(=O)c1cc(-c2ncccn2)ccc1Cl,,CO,,,,test
US20140315888A1,CN1CC2CNCC2C1.Clc1nc2cc(Br)cnc2nc1Cl>>CN1CC2CN(c3nc4ncc(Br)cc4nc3Cl)CC2C1,,ClCCl,,,,test
US20140094445A1,COC(=O)c1cccc(N2CCS(=O)(=O)CC2)c1.NN>>NNC(=O)c1cccc(N2CCS(=O)(=O)CC2)c1,,CO,,,,test
US05073556,O.[NH-]C(=O)c1cc(F)c(F)c(OC(F)F)c1F>>O=C(O)c1cc(F)c(F)c(OC(F)F)c1F,,O=S(=O)(O)O,,O=N[O-].[Na+],,test
US20140256756A1,CC(C)c1nsc(N2CCC(N3CCC(Oc4ccc(S(=O)(=O)CCCCl)cc4F)C3=O)CC2)n1>>CC(C)c1nsc(N2CCC(N3CCC(Oc4ccc(S(=O)(=O)C5CC5)cc4F)C3=O)CC2)n1,,C1CCOC1,,O,,test
US20130090298A1,CO.Cc1ccc(S(=O)(=O)OC[C@H]2O[C@@H](c3ccc(Cl)c(Cc4ncc(-c5ccco5)s4)c3)[C@H](O)[C@@H](O)[C@@H]2O)cc1>>COC[C@H]1O[C@@H](c2ccc(Cl)c(Cc3ncc(-c4ccco4)s3)c2)[C@H](O)[C@@H](O)[C@@H]1O,,CO,,C[O-].[Na+],,test
US20150368269A1,CCOC(=N)c1ccc2c(c1)S(=O)(=O)N=C([C@H](O)[C@H]1OCCN(c3ccc(C)cc3)C1=O)N2.N>>N=C(N)c1ccc2c(c1)S(=O)(=O)N=CN2,,CO,,,,test
US20110230458A1,COC1CCN(C(=O)OC(C)(C)C)CC1CN=[N+]=[N-]>>COC1CCN(C(=O)OC(C)(C)C)CC1CN,[Pd],CCOC(C)=O,,[H][H],,test
US05075299,O=c1cc(CO)occ1O>>Cc1cc(=O)c(O)co1,[Zn],O,,Cl,[Na+].[OH-],test
US05387709,N#CC1(Cc2ccccc2)CCCC1>>NCC1(Cc2ccccc2)CCCC1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(C(=O)C2C(=O)OC(C)(C)OC2=O)CC1.Cc1ccc(Cl)c2c(N)n[nH]c12>>Cc1ccc(Cl)c2c1nn1c(C3CCN(C(=O)OC(C)(C)C)CC3)cc(=O)[nH]c21,,CC#N,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20070244155A1,COc1ccc(COc2ccc(Br)c(C=O)c2)cc1>>COc1ccc(COc2ccc(Br)c(CO)c2)cc1,,CO,,[BH4-].[Na+],,test
US20030166628A1,CCC(Br)C(=O)c1cc2c(Cl)cccc2s1.S=C1NCCN1>>Br.CCC1=C(c2cc3c(Cl)cccc3s2)N2CCN=C2S1,,CC(=O)O,,CCO,,test
US20130116234A1,CCOC(=O)CC(=O)C(C)C.Nc1ccc(Cl)cc1C#Cc1ccccc1Cl>>CCOC(=O)c1c(C(C)C)nc2ccc(Cl)cc2c1Cc1ccccc1Cl,,CCO,CCOC(C)=O,,,test
US20040092582A1,C=C(C)Cc1cc(C=O)cc(OCC)c1O>>CCOc1cc(C=O)cc2c1OC(C)(C)C2,,Cc1ccccc1,,,,test
US20140008617A1,Brc1ccc(I)nc1.OB(O)c1ccccc1>>Brc1ccc(-c2ccccc2)nc1,,O,,COCCOC,O=C([O-])[O-].[K+].[K+],test
US04216238,CCN(CC)CCN.CCOC(=O)CCC(=O)Cl>>CCOC(=O)CCC(=O)NCCN(CC)CC,,ClCCl,,c1ccncc1,,test
US20120196864A1,CN1CCCC1CCN.COc1cc(/C=C2\NC(=O)N=C2N)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F>>COc1cc(/C=C2\NC(=O)N=C2NCCC2CCCN2C)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F,,CO,,,,test
US20050288258A1,CN1NN=CN1N.Cc1ncc(COP(=O)(O)O)c(C=O)c1O>>Cc1ncc(COP(=O)(O)O)c(C=NN2C=NNN2C)c1O,,CCO,,O,O,test
US20130267493A1,O=C(O)c1n[nH]c2cc(Cl)c(Br)cc12.OB(O)c1ccc2c(c1)OCCO2>>O=C(O)c1n[nH]c2cc(Cl)c(-c3ccc4c(c3)OCCO4)cc12,,CCO,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],,test
US20130040933A1,C[C@H](Nc1cncc(-c2cn(S(=O)(=O)c3ccccc3)c3ncc(Cl)cc23)n1)C(=O)NCC(F)(F)F>>C[C@H](Nc1cncc(-c2c[nH]c3ncc(Cl)cc23)n1)C(=O)NCC(F)(F)F,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20090029965A1,Cc1ccc2c(c1)Nc1c(cnn1C)CN2.Cc1ccccc1.Cc1nc2c(o1)-c1ccccc1NCC2.ClCCl.O=S(Cl)Cl>>Cc1ccc2c(c1)Nc1c(cnn1C)CN2C(=O)c1ccc(C#N)c(C)c1,,Cc1ccccc1,ClCCl,CCN(CC)CC,,test
US20160229814A1,CN(C)N.O=Cc1cc(=O)n(CC2CC2)c(=O)n1CC1CC1>>CN(C)N=Cc1cc(=O)n(CC2CC2)c(=O)n1CC1CC1,,CN(C)C=O,,,,test
US20140213580A1,N#Cc1cc(-c2cccnc2)c(C2CC2)nc1N1CCN[C@H](C2CC2)C1.O=C(O)CC(F)(F)F>>N#Cc1cc(-c2cccnc2)c(C2CC2)nc1N1CCN(C(=O)CC(F)(F)F)[C@H](C2CC2)C1,,CCN(CC)CC,ClCCl,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20060247266A1,Clc1ncc2c3c(cccc13)N(C1CCC3(CC1)OCCO3)CC2>>O=C1CCC(N2CCc3cnc(Cl)c4cccc2c34)CC1,,C1CCOC1,,Cl,,test
US04237136,CCOC(=O)C#CC(=O)OCC.Nc1nc(-c2ccccc2)cs1>>CCOC(=O)c1cc(=O)nc2scc(-c3ccccc3)n12,,C1CCOC1,,,,test
US20060106081A1,CCCc1nc2cc(NCc3ccccc3)ccc2n1CC(=O)OC(C)(C)C.O=C(Cl)c1ccccc1F>>CCCc1nc2cc(N(Cc3ccccc3)C(=O)c3ccccc3F)ccc2n1CC(=O)OC(C)(C)C,CN(C)c1ccncc1,Cl,ClCCl,CCN(C(C)C)C(C)C,,test
US20150166569A1,CCOC(=O)c1nc2c(s1)C(CO)COc1ccc(Br)cc1-2.ClCCl>>CCOC(=O)c1nc2c(s1)C(COC)COc1ccc(Br)cc1-2,O=[Ag],,,,,test
US20100160308A1,CCOC(=O)c1sc(-n2cnc3cc(CN4CCN(C)CC4)ccc32)nc1-c1cccc(Cl)c1>>CN1CCN(Cc2ccc3c(c2)ncn3-c2nc(-c3cccc(Cl)c3)c(C(=O)O)s2)CC1,,C1CCOC1,O,[Li+].[OH-],,test
US20110130400A1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2C(=O)[C@@H](NC(=O)c1cc2ccccc2[nH]1)C(C)(C)C>>CC(C)(C)[C@H](NC(=O)c1cc2ccccc2[nH]1)C(=O)N1C[C@@H]2C[C@H]1CN2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040157886A1,CC(Cl)Cl.Nc1cccc(NC(=O)C(=O)N2CCC(Cc3ccc(F)cc3)CC2)c1.O=Cc1ccccc1>>Cl.O=C(Nc1cccc(NCc2ccccc2)c1)C(=O)N1CCC(Cc2ccc(F)cc2)CC1,,O=C([O-])O,[Na+],CC(=O)O,,test
US05968954,CN(C1CCNCC1)C1Cc2ccccc2C1.Clc1ccnc2c1OCCO2>>CN(C1CCN(c2ccnc3c2OCCO3)CC1)C1Cc2ccccc2C1,,Cc1ccccc1,,c1ccncc1,,test
US20030158226A1,CCCCN(C(=O)Cl)c1ccc2c(c1)C(C)(C)CCC2(C)C.CCOC(=O)c1ccc(N)cc1>>CCCCN(C(=O)Nc1ccc(C(=O)OCC)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C,,c1ccncc1,,,,test
US20100183513A1,Cc1ccc(-c2cnc(NC(=O)c3cnc(Br)s3)s2)cc1.NCc1ccccc1>>Cc1ccc(-c2cnc(NC(=O)c3cnc(NCc4ccccc4)s3)s2)cc1,,CCOC(C)=O,CN(C)C=O,,,test
US20110118248A1,CC(=O)c1cc(N)ccc1Cl.Cl.O=S=O>>CC(=O)c1cc(S(=O)(=O)Cl)ccc1Cl,Cl[Cu],CC(=O)O,O,O=N[O-].[Na+],,test
US05629007,C[C@]12CCC(=O)N[C@@H]1CCc1cc(-c3cccc([N+](=O)[O-])c3)ccc12>>C[C@]12C=CC(=O)N[C@@H]1CCc1cc(-c3cccc([N+](=O)[O-])c3)ccc12,,C1COCCO1,CCOC(C)=O,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20160002251A1,COCCN(C)CCOc1ccc(C=O)c(F)c1F.Cl>>COCCN(C)CCOc1ccc(C=O)c(F)c1F.Cl,,COCCOC,,c1ccncc1,,test
US08350090B1,COc1cccc(CC(=O)O)c1.c1ccoc1>>COc1cccc(CC(=O)c2ccco2)c1,,ClCCl,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US20060089344A1,CC(C)C[Zn]Br.O=C1COC(=O)N1CCC1CCN(c2cccc(Br)n2)CC1>>CC(C)Cc1cccc(N2CCC(CCN3C(=O)COC3=O)CC2)n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,,CCOC(C)=O,O,test
US04820729,CCOC(=O)CNc1ccc2c(c1)CCC2.C[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CCOC(=O)CN(C(=O)[C@H](C)NC(=O)OCc1ccccc1)c1ccc2c(c1)CCC2,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04027023,CCOC(=O)c1nnc2ccc(-c3ccccc3)cc2c1O>>CCOC(=O)c1cc2cc(-c3ccccc3)ccc2nn1,CN(C)C=O,,,O=S(Cl)Cl,,test
US20030153604A1,CI.COc1ccc(-c2ccc(C(=O)NCCc3ccc4[nH]cc(C#N)c4c3)cc2)cn1>>COc1ccc(-c2ccc(C(=O)NCCc3ccc4c(c3)c(C#N)cn4C)cc2)cn1,,CN(C)C=O,,[H-].[Na+],,test
US20140235628A1,O=C(O)Cc1ccc(-n2cnnn2)cc1.O=C1OCCc2cc(CCC3CCNCC3)ccc21>>O=C1OCCc2cc(CCC3CCN(C(=O)Cc4ccc(-n5cnnn5)cc4)CC3)ccc21,,ClCCl,,CCN(CC)CC,ClCCCl,test
US04886805,FC(F)(F)c1cccc(N2CCN(CCCl)CC2)c1.FC(F)(F)c1cccn2c(S)nnc12.O=C(O)/C=C\C(=O)O>>FC(F)(F)c1cccc(N2CCN(CCSc3nnc4c(C(F)(F)F)cccn34)CC2)c1.O=C(O)/C=C\C(=O)O,,CC(C)=O,CCO,CCN(CC)CC,,test
US20080045542A1,NC(=O)c1[nH]cnc1-c1ccc([N+](=O)[O-])cc1>>NC(=O)c1[nH]cnc1-c1ccc(N)cc1,[Pd],CO,,[H][H],,test
US20100105727A1,COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(CCC#N)C[C@H]1OC.NO>>COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(CCC(N)=NO)C[C@H]1OC,,CCO,,Cl,O=C([O-])O.[Na+],test
US20090012055A1,COc1ccccc1CCOCCO.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1ccccc1CCOCCOS(=O)(=O)c1ccc(C)cc1,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20130281434A1,Cc1cc2nc(-c3cccc(OCc4ccccc4)c3)sc2c(Br)c1[C@@H](COC(=O)C(C)(C)C)OC(C)(C)C.OB(O)c1ccc(Cl)cc1>>Cc1cc2nc(-c3cccc(OCc4ccccc4)c3)sc2c(-c2ccc(Cl)cc2)c1[C@@H](COC(=O)C(C)(C)C)OC(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20090240052A1,COS(=O)(=O)OC.O=C(Nc1cc(I)ccc1C(=O)O)c1ccccc1>>COC(=O)c1ccc(I)cc1NC(=O)c1ccccc1,,CCOC(C)=O,CN(C)C=O,Cl,O=C([O-])[O-].[K+].[K+],test
US20130338159A1,CN(C)/C=C(\C(=O)CC1CC1)c1ccnc(Nc2ccncc2)n1.N=C(N)N>>Nc1ncc(-c2ccnc(Nc3ccncc3)n2)c(CC2CC2)n1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20090062125A1,CC(=O)c1cc(Br)ccc1Cl>>CC(O)c1cc(Br)ccc1Cl,,CO,,[BH4-].[Na+],,test
US20040121994A1,CCOC(=O)/C=C/c1ccccc1Sc1ccc(Cl)cc1Cl>>O=C(O)/C=C/c1ccccc1Sc1ccc(Cl)cc1Cl,,C1COCCO1,CO,O,[Na+].[OH-],test
US20030195354A1,C#CCCl.COc1ccc(CCNC(=O)C(=CO)c2ccc(C)cc2)cc1OC>>C#CCOC=C(C(=O)NCCc1ccc(OC)c(OC)c1)c1ccc(C)cc1,,O,,CN(C)C=O,[H-].[Na+],test
US20160237090A1,CC(F)(F)c1cccc(N)c1.O=C(Cl)Oc1ccccc1>>CC(F)(F)c1cccc(NC(=O)Oc2ccccc2)c1,,C1CCOC1,ClCCl,O,c1ccncc1,test
US20100164489A1,CC(=O)OC[C@H]1O[C@@H](OCc2ccc([N+](=O)[O-])cc2)[C@H](N2C(=O)c3ccccc3C2=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>O=C1c2ccccc2C(=O)N1[C@H]1[C@H](OCc2ccc([N+](=O)[O-])cc2)O[C@H](CO)[C@@H](O)[C@@H]1O,,ClCCl,,C[O-].[Na+],,test
US05693655,COC(=O)c1ccc2[nH]cc(CCCCN3CCC(c4c[nH]c5ccc(C(=O)OC)cc45)CC3)c2c1>>O=C(O)c1ccc2[nH]cc(CCCCN3CCC(c4c[nH]c5ccc(C(=O)O)cc45)CC3)c2c1,,[K+],[OH-],,,test
US20150133428A1,CC(C)(C(=O)O)C(F)F.NC(=O)c1c(-c2ccc(F)c(Cl)c2)nn2c1CNCC2.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(NC(=O)N1CCn2nc(-c3ccc(F)c(Cl)c3)c(C(N)=O)c2C1)C(F)F,,CCOC(C)=O,Cc1ccccc1,C1CCOC1,,test
US20060100262A1,CN(C)CCN.COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccsc3C=O)n(CC(=O)OC(C)(C)C)c2c1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccsc3CNCCN(C)C)n(CC(=O)OC(C)(C)C)c2c1,,C1CCOC1,CCOC(C)=O,CC(=O)O,[BH3-]C#N.[Na+],test
US20130131017A1,CCOCCl.Cc1cc(Br)c(C(C)(C)O)cc1Cl>>CCOCOC(C)(C)c1cc(Cl)c(C)cc1Br,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US04863920,CN1Cc2c(Cl)cccc2-n2c(c(/C=C\Cl)[nH]c2=O)C1>>C#Cc1ncn2c1CN(C)C(=O)c1c(Cl)cccc1-2,,CN(C)C=O,,C1CCC2=NCCCN2CC1,O,test
US06093744,CC(C)c1cc(C(C)C)c(CC(=O)O)c(C(C)C)c1.CC(C)c1cc([N+](=O)[O-])cc(C(C)C)c1OS(N)(=O)=O>>CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(C(C)C)cc([N+](=O)[O-])cc2C(C)C)c(C(C)C)c1,CN(C)C=O,Cc1ccccc1,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20120058985A1,CC(=O)Nc1nccc(Oc2cc(F)c(N)cc2F)n1.O=C(O)C1(C(=O)Nc2ccc(F)cc2)CC1>>CC(=O)Nc1nccc(Oc2cc(F)c(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)n1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020165241A1,O=C(OCc1ccccc1)N1CCC(CNc2ccncc2)CC1>>c1cc(NCC2CCNCC2)ccn1,[Pd],CCO,,[H][H],,test
US20100273755A1,CN(CCCNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC(C)(C)C.Cl>>CNCCCNC(=O)OCC1c2ccccc2-c2ccccc21.Cl,,CCOC(C)=O,,,,test
US20110201604A1,CCOC(=O)c1ccc2nc(Nc3nc4ccc(OC(F)(F)F)cc4s3)n(C)c2c1>>Cn1c(Nc2nc3ccc(OC(F)(F)F)cc3s2)nc2ccc(C(=O)O)cc21,,C1CCOC1,CO,[Na+].[OH-],,test
US20110136763A1,CCOC(=O)C(C)C1OB(O)c2cc(Oc3nnc(N)s3)cc(C)c21>>Cc1cc(Oc2nnc(N)s2)cc2c1C(C(C)C(=O)O)OB2O,,C1CCOC1,O,[Li+].[OH-],,test
US06399616B1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.O=c1[nH]ccc2occc12>>O=S(=O)(c1nccc2occc12)C(F)(F)F,,ClCCl,,O,c1ccncc1,test
US20110288120A1,CC[C@H](Nc1oc(=O)c2ccccc2c1C(C)=O)c1ccccc1.NNc1ccccc1>>CC[C@H](NC(=O)c1c(C)n(Nc2ccccc2)c(=O)c2ccccc12)c1ccccc1,,CC#N,,,,test
US20040127720A1,CC(=O)C(C)=NO.CI.[O-][n+]1cc[nH]c1.c1ccc(CN2CN(Cc3ccccc3)CN(Cc3ccccc3)C2)cc1>>CO[n+]1cn(Cc2ccccc2)c(C)c1C.[I-],,ClC(Cl)Cl,,,,test
US20060046992A1,N[C@H](CO)Cc1ccccc1.O=C(O)c1ccc(Cl)nc1Cl>>O=C(O)c1ccc(Cl)nc1N[C@H](CO)Cc1ccccc1,,C1COCCO1,,CCN(CC)CC,O,test
US20110005947A1,CCOC(=O)c1cnc(SC)nc1Cl.NC1(c2ccccc2)CC1>>CCOC(=O)c1cnc(SC)nc1NC1(c2ccccc2)CC1,,CC#N,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20100022589A1,NC1CCCCC1.O=C(Cl)c1cccnc1Cl>>O=C(NC1CCCCC1)c1cccnc1Cl,,ClCCl,ClCCl,CCN(CC)CC,O,test
US20080261969A1,CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CN(OC(C)(C)C)C1)C2c1ccc(Sc2nc3cc(F)c(Cl)cc3[nH]2)o1.Cl>>CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CNC1)C2c1ccc(Sc2nc3cc(F)c(Cl)cc3[nH]2)o1.Cl,,C1COCCO1,,,,test
US05834261,CCOC(=O)[C@@H](CC)[C@H](C)O.N>>CC[C@H](C(N)=O)[C@H](C)O,,CCO,,,,test
US20020151713A1,CCC(N)CC.Cc1cc(C)c(-c2c(C)nn3c(Cl)cc(C)nc23)c(C)c1>>CCC(CC)Nc1cc(C)nc2c(-c3c(C)cc(C)cc3C)c(C)nn12,,CN1CCCC1=O,,,,test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCC1CCN(C)CC1.Oc1ccc2[nH]c(C(F)(F)F)cc2c1>>COc1cc2c(Oc3ccc4[nH]c(C(F)(F)F)cc4c3)ncnc2cc1OCC1CCN(C)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110201584A1,C[C@]12CC[C@H](OC(=O)Oc3ccc([N+](=O)[O-])cc3)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](c3ccc(=O)oc3)CC[C@]12O.NCCN1CCCC1>>C[C@]12CC[C@H](OC(=O)NCCN3CCCC3)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](c3ccc(=O)oc3)CC[C@]12O,,ClCCl,,,,test
US20130102603A1,O=[N+]([O-])c1ccc(-c2cc(-c3ccccc3F)nc3ncccc23)c2ccncc12.OCCO>>OCCOc1ccc(-c2cc(-c3ccccc3F)nc3ncccc23)c2ccncc12,,O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040054173A1,NC1CCN(Cc2ccccc2)CC1.O=Cc1ccncc1>>C(=NC1CCN(Cc2ccccc2)CC1)c1ccncc1,,CCO,,,,test
US20050187236A1,CNC(=O)Oc1ccccc1.c1ccc(COc2ccc3[nH]ccc3c2)cc1>>CNC(=O)n1ccc2cc(OCc3ccccc3)ccc21,,CN(C)C=O,,O,[H-].[Na+],test
US04287341,C1COCCN1.COc1ccc2c(N)nc(Cl)nc2c1OC>>COc1ccc2c(N)nc(N3CCOCC3)nc2c1OC.Cl,,CCC(C)=O,,,,test
US20060173018A1,CC(C)C[C@@H](O)C(=O)N1CCNCC1.Cc1ccc2c(Cl)nc(Cl)nc2c1>>Cc1ccc2c(N3CCN(C(=O)[C@H](O)CC(C)C)CC3)nc(Cl)nc2c1,,ClCCl,,CCN(CC)CC,,test
US20050113379A1,COc1nc(C(C)C)ccc1-c1nc2c(C)cn([C@@H]3CNC[C@@H]3OCCF)c2cc1C.O=C(n1ccnc1)n1ccnc1.OCCN1CCOCC1>>COc1nc(C(C)C)ccc1-c1nc2c(C)cn([C@@H]3CN(C(=O)OCCN4CCOCC4)C[C@@H]3OCCF)c2cc1C,,ClCCl,,,,test
US05854179,CCSc1ccc([N+](=O)[O-])cc1S(=O)(=O)NC(C)(C)C>>CCSc1ccc(N)cc1S(=O)(=O)NC(C)(C)C,[Zn],CCO,,O,[Cl-].[NH4+],test
US20100087429A1,NC1=N[C@]2(CO1)c1cc(Br)ccc1Oc1ccc(I)cc12.OB(O)c1cncnc1>>NC1=N[C@]2(CO1)c1cc(Br)ccc1Oc1ccc(-c3cncnc3)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20060100207A1,C=CCOC(=O)CC(C)=O.CC1(C)OC(=O)CC(=O)O1.N#Cc1ccc(C=O)cc1.Nc1cccc(C(F)(F)F)c1>>C=CCOC(=O)C(C(C)=O)C(CC(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(C#N)cc1,,C1CCOC1,,[F-].[K+],,test
US20090036449A1,CCOc1c(Nc2ccc3c(c2)c(NC(=O)c2ccccc2)nn3C(=O)OC(C)(C)C)c(=O)c1=O.COc1cccc([C@@H](C)N)c1>>COc1cccc([C@@H](C)Nc2c(Nc3ccc4c(c3)c(NC(=O)c3ccccc3)nn4C(=O)OC(C)(C)C)c(=O)c2=O)c1,,CCO,,CCN(CC)CC,,test
US20110251181A1,CC(C)(C)OC(=O)N1CCCNCC1.CC(C)O.C[C@@H]1C[C@@H](OC(=O)c2ccc([N+](=O)[O-])cc2)c2ncnc(Cl)c21>>C[C@@H]1C[C@@H](OC(=O)c2ccc([N+](=O)[O-])cc2)c2ncnc(C3CCCN(C(=O)OC(C)(C)C)CC3)c21,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20010018422A1,CC(C)(C)OC(=O)N[C@H]1CCC[C@H]1C(=O)NCc1ccccc1.Cl>>Cl.N[C@H]1CCC[C@H]1C(=O)NCc1ccccc1,,CCOCC,ClCCl,,,test
US20020042415A1,CC(C)(C)OC(=O)NC(C)(C)C(=O)N[C@H](CCCc1ccccc1)C(=O)N1CCN2C(=O)N(CC(F)(F)F)C(=O)[C@]2(Cc2ccccn2)C1.Cl>>CC(C)(N)C(=O)N[C@H](CCCc1ccccc1)C(=O)N1CCN2C(=O)N(CC(F)(F)F)C(=O)[C@]2(Cc2ccccn2)C1.Cl,,CCO,,,,test
US20130096118A1,CC[N+](=O)[O-].Cc1c(C=O)cccc1NC(=O)OCc1ccccc1>>C/C(=C\c1cccc(NC(=O)OCc2ccccc2)c1C)[N+](=O)[O-],,CC(=O)O,,C,O=C[O-].[NH4+],test
US20100130466A1,CC(C)(C)OC(=O)Nc1cnc(F)cc1I>>Nc1cnc(F)cc1I,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150344473A1,CC(C)(C)OC(=O)N1CCC(O)C(F)(F)C1.COc1cc(-c2cc3c(-c4ccc(F)c(C#N)c4)ncnc3[nH]2)ccc1N1CCN(C2COC2)CC1>>COc1cc(-c2cc3c(-c4ccc(OC5CCN(C(=O)OC(C)(C)C)CC5(F)F)c(C#N)c4)ncnc3[nH]2)ccc1N1CCN(C2COC2)CC1,,O,,CC(C)(C)[O-].[K+],,test
US20100256163A1,CCI.Oc1c(OC(F)(F)F)cccc1C1CCNCC1>>CCN1CCC(c2cccc(OC(F)(F)F)c2O)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080153843A1,C1CCN(CCC2CCNCC2)C1.COc1cc(C)c(S(=O)(=O)N2CCCC2COCC(=O)O)c(C)c1>>COc1cc(C)c(S(=O)(=O)N2CCCC2COCC(=O)N2CCC(CCN3CCCC3)CC2)c(C)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20080027070A1,Cc1cc(C(=O)Cl)no1.Nc1ccc(Cl)c(C(=O)O)c1>>Cc1cc(C(=O)Nc2ccc(Cl)c(C(=O)O)c2)no1,,ClCCl,,,,test
US20090247526A1,Cc1ccc(N=C=S)c(Cl)n1.Nc1cc(Oc2c(F)cccc2F)ccn1>>Cc1ccc2nc(Nc3cc(Oc4c(F)cccc4F)ccn3)sc2n1.Cl,,CN(C)C=O,,,,test
US20010034343A1,COC(=O)c1cc(C=O)ccc1OC.NO>>COC(=NO)c1cc(C=O)ccc1OC,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20110263548A1,C[C@H]1C[C@@H](Oc2ccn(-c3ccc(S(C)(=O)=O)cc3)c(=O)c2)CCN1C(=O)OC(C)(C)C.Cl>>C[C@H]1C[C@@H](Oc2ccn(-c3ccc(S(C)(=O)=O)cc3)c(=O)c2)CCN1.Cl,,CO,,,,test
US04241072,CC(=O)Nc1nc(C)cs1.CN(C)CCCl>>CC(=O)N(CCN(C)C)c1nc(C)cs1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20150246923A1,N#CCC(=O)C1CC1.NNC1CC1>>Nc1cc(C2CC2)nn1C1CC1,,CCO,,Cl,CC(=O)[O-].[Na+],test
US04440772,CC(C)[C@@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C=C4c5cccc6[nH]cc(c56)C[C@@H]4N(C)C3)(C(C)C)C(=O)N12.CS(=O)(=O)O>>CC(C)[C@@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C=C4c5cccc6[nH]cc(c56)C[C@@H]4N(C)C3)(C(C)C)C(=O)N12.CS(=O)(=O)O,,CCO,,CCOCC,,test
US20130225553A1,CC(=O)c1cc(Br)c(C(F)(F)F)cc1N.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(=O)c1cc(Br)c(C(F)(F)F)cc1NC(=O)C(F)(F)F,,ClCCl,,CCN(CC)CC,O,test
US20050070562A1,CC(C)OC(=O)N1CCC(Oc2ncnc(Nc3ccc(I)cc3F)c2C#N)CC1.CCCN>>CCCNc1ccc(Nc2ncnc(OC3CCN(C(=O)OC(C)C)CC3)c2C#N)c(F)c1,I[Cu]I,CS(C)=O,,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US05290949,CCC(=O)CN(C(=O)Cc1cccc(F)c1)c1ccc(Cl)c(C(F)(F)F)c1>>CCC1=C(c2cccc(F)c2)C(=O)N(c2ccc(Cl)c(C(F)(F)F)c2)C1,,CCO,,O,[Na+].[OH-],test
US20070287725A1,C#CCNc1c(C)c(C)nc(Cl)c1[N+](=O)[O-].ON=C(Cl)c1ccc(F)cc1>>Cc1nc(Cl)c([N+](=O)[O-])c(NCc2cc(-c3ccc(F)cc3)no2)c1C,,ClCCl,,CCN(CC)CC,,test
US20030162767A1,ClCc1ccccc1.Oc1ccccc1Br>>Brc1ccccc1OCc1ccccc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04455422,O=c1ccc2cc(C=CCCN3CCN(c4ccccc4)CC3)ccc2[nH]1>>O=c1ccc2cc(CCCCN3CCN(c4ccccc4)CC3)ccc2[nH]1,[Pd],CCO,,,,test
US20150376172A1,C[C@@]1(c2cc(Br)cs2)C[C@@H](C(F)(F)F)OC(N)=N1.OB(O)c1cncnc1>>C[C@@]1(c2cc(-c3cncnc3)cs2)C[C@@H](C(F)(F)F)OC(N)=N1,,COCCOC,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,O=C([O-])[O-].[Na+].[Na+],test
US20140080807A1,CN1CCN(c2ccc(C(=O)Nc3nn(C(=O)OC(C)(C)C)c4cc(OCc5cccc(Oc6ccccc6)c5)ccc34)cc2)CC1>>CN1CCN(c2ccc(C(=O)Nc3n[nH]c4cc(OCc5cccc(Oc6ccccc6)c5)ccc34)cc2)CC1,,ClCCl,O=C(O)C(F)(F)F,CO,,test
US20150284405A1,CC1(C)OC[C@@H]2CCC(=O)N21.CI>>CC1C[C@H]2COC(C)(C)N2C1=O,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20040006071A1,CCN1c2ncc(CCOc3ccc(C(=O)O)cc3C)cc2C(=O)N(C)c2cccnc21.O=C(Cl)C(=O)Cl>>CCN1c2ncc(CCOc3ccc(C(=O)Cl)cc3C)cc2C(=O)N(C)c2cccnc21,,ClCCl,,CN(C)C=O,,test
US05300514,O=C1NN(C(=O)Nc2ccc([N+](=O)[O-])cc2)C(c2ccccc2)C1c1ccccc1>>Nc1ccc(NC(=O)N2NC(=O)C(c3ccccc3)C2c2ccccc2)cc1,[Pd],CCO,,,,test
US20150291595A1,CC1(C)OB(c2ccc(NS(C)(=O)=O)cc2)OC1(C)C.Cc1ccn2nc([C@H](C)Nc3ncnc4c3c(Br)cn4COCC[Si](C)(C)C)n(-c3ccccc3)c(=O)c12>>Cc1ccn2nc([C@H](C)Nc3ncnc4c3c(-c3ccc(NS(C)(=O)=O)cc3)cn4COCC[Si](C)(C)C)n(-c3ccccc3)c(=O)c12,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20040029874A1,CS(=O)(=O)Cl.ClCCl.Nc1ccc(NCC2CCN(c3ccncc3)CC2)c(C(=O)Nc2ccc(Cl)cn2)c1>>CS(=O)(=O)Nc1ccc(NCC2CCN(c3ccncc3)CC2)c(C(=O)Nc2ccc(Cl)cn2)c1.Cl.Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160030395A1,Cc1noc(C)c1-c1ccc2c(c1)C(O)(c1ccsc1)C(=O)N2>>Cc1noc(C)c1-c1ccc2c(c1)C(c1ccsc1)C(=O)N2,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20150175530A1,CCOC(=O)[C@@H](N)[C@@H](N[S@@](=O)C(C)(C)C)C(F)(F)F.C[C@H](O)C#CC#Cc1ccc(C(=O)O)cc1>>CCOC(=O)[C@@H](NC(=O)c1ccc(C#CC#C[C@H](C)O)cc1)[C@@H](N[S@@](=O)C(C)(C)C)C(F)(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130184320A1,NC(=O)NNCC(F)(F)F.O=Cc1ccc(N2CC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)OC2=O)cc1Cl>>O=C(NCC(F)(F)F)N/N=C/c1ccc(N2CC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)OC2=O)cc1Cl,,CC(=O)O,CCO,Cl,,test
US05801201,C=CCOC1CCC2(CC1)OCCO2>>C=CCOC1CCC(=O)CC1,,CCOCC,,Cl,O=C([O-])O.[Na+],test
US20120277262A1,CCCNC1CCc2cccc(OC)c2C1>>CCCN[C@@H]1CCc2cccc(OC)c2C1,,CCO,,,,test
US20140179680A1,CC1(C)OB(c2cc(Cl)cnc2F)OC1(C)C.C[C@@H]1CC[C@@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(Cl)nc(Cl)c32)CC1>>C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3cc(Cl)nc(-c4cc(Cl)cnc4F)c32)CC1,,CCOC(C)=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100004235A1,COc1ccc(Cn2c(-c3nn(Cc4ccccc4F)c4ncccc34)n[nH]c2=O)c(OC)c1.OCCI>>COc1ccc(Cn2c(-c3nn(Cc4ccccc4F)c4ncccc34)nn(CCO)c2=O)c(OC)c1,,CN(C)C=O,O,[H-].[Na+],,test
US04070539,C=C(CC(C)C)C(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl>>CC(C)CC1Cc2cc(OCC(=O)O)c(Cl)c(Cl)c2C1=O,,O,,O=S(=O)(O)O,,test
US20060122184A1,CCOC(=O)C(CC(CC)CC)(NC(=O)OCc1ccccc1)C(=O)O>>CCC(CC)CC(NC(=O)OCc1ccccc1)(C(=O)O)C(=O)O,,CCO,,[Na+].[OH-],,test
US05856309,CCOC(=O)C1CN(C(=O)OC(C)(C)C)CC1OC(=O)c1ccccc1>>CCOC(=O)C1=CCN(C(=O)OC(C)(C)C)C1,,Cc1ccccc1,,C1CCC2=NCCCN2CC1,,test
US07071175B1,CCOC(=O)C(Cc1ccnc(NC(=O)OC(C)(C)C)c1)C(=O)OCC>>CCOC(=O)C(Cc1ccnc(NC(=O)OC(C)(C)C)c1)C(=O)O,,CCO,ClCCl,[K+].[OH-],,test
US04259469,C=C(C)C(=O)Cl.Cc1cc(O)ccc1NS(C)(=O)=O>>C=C(C)C(=O)Oc1ccc(NS(C)(=O)=O)c(C)c1,,ClCCl,,CCN(CC)CC,,test
US20040116699A1,N#CCc1ccccc1Cl.NC(=O)CCC(=O)NBr>>N#CC(Br)c1ccccc1Cl,CC(C)(C#N)N=NC(C)(C)C#N,CCOC(C)=O,,,,test
US20080021056A1,COC(OC)N(C)C.NN.O=C1CCN(S(=O)(=O)c2ccc(Cl)cc2)c2ccc(Cl)cc21>>O=S(=O)(c1ccc(Cl)cc1)N1Cc2cn[nH]c2-c2cc(Cl)ccc21,,CC(=O)O,,O,,test
US20100305123A1,CC(=O)c1ccc(CN2CCN(C)CC2)cc1.CC(C)(C)OC(=O)/C=C/c1cccc(C=O)n1>>CN1CCN(Cc2ccc(C(=O)/C=C/c3cccc(/C=C/C(=O)OC(C)(C)C)n3)cc2)CC1,,C1CCOC1,,[K+].[OH-],,test
US20150344473A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.N#Cc1cc(Br)ccc1N1CCCC1=O>>N#Cc1cc(B(O)O)ccc1N1CCCC1=O,,C1COCCO1,,ClCCl,CC(=O)[O-].[K+],test
US04735951,CC(C)C(Cl)C(=O)Cl.Nc1c(C(=O)O)cccc1C(F)(F)F>>CC(C)C(Cl)c1nc2c(C(F)(F)F)cccc2c(=O)o1,,Cc1ccccc1,,,,test
US03931323,CC1=CCCC(C)(C)C1C1OC1C(C)=NO>>CC1=CCCC(C)(C)C1c1cc(C)no1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20160159820A1,N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5c4CCC(=O)N5)cc3[C@@H]12.O=C(O)c1cc(C(F)(F)F)ccn1>>O=C1CCc2c(Oc3ccc4c(c3)[C@H]3[C@H](NC(=O)c5cc(C(F)(F)F)ccn5)[C@H]3O4)ccnc2N1,,ClCCl,O=S(Cl)Cl,CCN(C(C)C)C(C)C,,test
US04786646,O=S(Cl)Cl.OCCCCCc1ccccn1>>ClCCCCCc1ccccn1,,ClCCl,,[Na+].[OH-],,test
US20020115674A1,C1CCNC1.Cc1ccc(-n2c(=O)n(OCc3ccccc3)c(=O)c3cc(F)c(Cl)nc32)cc1>>Cc1ccc(-n2c(=O)n(OCc3ccccc3)c(=O)c3cc(F)c(N4CCCC4)nc32)cc1,,CC#N,,CCN(CC)CC,,test
US05017724,Cc1cc(C)c2c(c1O)C(N)C1CCCCC21.O=C(Cl)CCCCl>>Cc1cc(C)c2c(c1O)C(N1CCCC1=O)C1CCCCC21,,O,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20060270637A1,CN(CCCCC(=O)OC[C@@H]1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1)C(=O)OC(C)(C)C>>CNCCCCC(=O)OC[C@@H]1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1,,CO,,CC(=O)O,Cl,test
US20070219181A1,COC(=O)CCCC(NNC(=O)OC(C)(C)C)c1ccc(F)cc1>>CC(C)(C)OC(=O)NN1C(=O)CCCC1c1ccc(F)cc1,,CO,,Cl,[Na+].[OH-],test
US04739049,O=c1[nH]c2ccc(Cl)cc2c(-c2ccccc2F)c1CO>>O=C1Oc2ccc(Cl)cc2C2=c3ccccc3=NCC12,,O,,CN(C)C=O,,test
US20060041146A1,COc1ccc([C@@H](NC(=O)OC(C)(C)C)C(=O)N[C@H](C(=O)Nc2nc(C(C)=O)cs2)[C@@H](C)c2ccccc2)cc1>>COc1ccc([C@@H](N)C(=O)N[C@H](C(=O)Nc2nc(C(C)=O)cs2)[C@@H](C)c2ccccc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040180925A1,CC1(NC(=O)OC(C)(C)C)CCN(c2cc(Cl)ncn2)CC1>>CC1(N)CCN(c2ccncn2)CC1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20140275079A1,Cc1[nH]c(-c2c(F)cccc2F)cc1C(=O)OC(C)(C)C>>Cc1[nH]c(-c2c(F)cccc2F)cc1C(=O)O,,C1COCCO1,,Cl,,test
US20120077799A1,Nc1ncccc1Br.OB(O)c1ccc2ccccc2c1>>Nc1ncccc1-c1ccc2ccccc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US06232310B1,CC(=O)Nc1cc(C(F)(F)F)ccc1S(=O)(=O)CC#N>>CC1=C(C#N)S(=O)(=O)c2ccc(C(F)(F)F)cc2N1,,CO,,[Br-].[K+],,test
US20070225267A1,CC(=O)OC(C)=O.CC(C)(F)CO[C@H]1CN(C(=O)OC(C)(C)C)[C@@H]([C@@H](O)[C@@H](N)Cc2cc(F)cc(F)c2)CO1>>CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)[C@H]1CO[C@@H](OCC(C)(C)F)CN1C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20030195221A1,C[C@H](Nc1cc(-c2nc(C3CCN(C(=O)OC(C)(C)C)CC3)n3cnnc3c2-c2cccc(C(F)(F)F)c2)ccn1)c1ccccc1>>C[C@H](Nc1cc(-c2nc(C3CCNCC3)n3cnnc3c2-c2cccc(C(F)(F)F)c2)ccn1)c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160083362A1,CC(C)(C)OC(=O)N1CCC[C@@H]1CCc1cccc(F)c1>>Fc1cccc(CC[C@H]2CCCN2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080194549A1,CC(C)N.CCOC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1C=O>>CCOC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1CNC(C)C,,ClCCCl,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04496720,C[Si](C)(C)Sc1ccc(Cl)cc1.O=[N+]([O-])c1ccc(CBr)cc1>>O=[N+]([O-])c1ccc(CSc2ccc(Cl)cc2)cc1,,CN(C)P(=O)(N(C)C)N(C)C,,CC#N,,test
US04238621,COC(=O)c1ccccc1S(=O)(=O)N=C=O.COc1cc(OC)nc(N)n1>>COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1,,O,,ClCCl,[Na+].[OH-],test
US20160263133A1,COC(=O)c1cc(C=O)ccc1O.COP([O-])OC.COc1ccc2nc(N)sc2c1>>COC(=O)c1cc(C(Nc2nc3ccc(OC)cc3s2)P(=O)(OC)OC)ccc1O,,CCOC(C)=O,Cc1ccccc1,ClCCl,,test
US04861878,CCOC(=O)C(Cl)C=O.Nc1cccnc1S>>CCOC(=O)C1=CNc2cccnc2S1,,CCO,,[K+].[OH-],,test
US20090264431A1,COc1ccc(OC)c(S(=O)(=O)N[C@@H]2C[C@H](CN)N(C(=O)OC(C)(C)C)C2)c1.O=C(Cl)Oc1ccccc1>>COc1ccc(OC)c(S(=O)(=O)N[C@@H]2C[C@H](CNC(=O)Oc3ccccc3)N(C(=O)OC(C)(C)C)C2)c1,,C1CCOC1,ClCCl,,,test
US20040110945A1,CCOC(=O)Cc1cc(Cl)c(NC(=O)c2c3ccccc3nn2C)cc1F>>Cn1nc2ccccc2c1C(=O)Nc1cc(F)c(CC(=O)O)cc1Cl,,Cl,,C1CCOC1,[Na+].[OH-],test
US20050080091A1,CCOC(=O)COc1ccc(CCCCNC(=O)OCc2ccccc2)cc1.OCCNCCO>>O=C(NCCCCc1ccc(OCC(=O)N(CCO)CCO)cc1)OCc1ccccc1,,CCO,,,,test
US06071928,CC(C)Oc1ccc(N)cc1Br.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)Oc1ccc(NC(=O)C(F)(F)F)cc1Br,,ClCCl,,CCN(CC)CC,,test
US20090270361A1,COC(=O)c1nnc(-c2ccc(Cc3c(C)nn(-c4ccc(C#N)c(Cl)c4)c3C)cc2)o1.C[Mg]Br>>CC(=O)c1nnc(-c2ccc(Cc3c(C)nn(-c4ccc(C#N)c(Cl)c4)c3C)cc2)o1,,C1CCOC1,,[Cl-].[NH4+],,test
US20020147333A1,CCOC(=O)c1cc(C)n(C)n1.[Li]C>>CC(=O)c1cc(C)n(C)n1,,C1CCOC1,,C[Si](C)(C)Cl,,test
US20060287297A1,N#Cc1cccc2c1Oc1ccccc1C2=C1CC2CCC(C1)N2C(=O)C(F)(F)F.NO>>N=C(NO)c1cccc2c1Oc1ccccc1C2=C1CC2CCC(C1)N2C(=O)C(F)(F)F,,CCO,,CCN(CC)CC,Cl,test
US20140187529A1,COC(=O)CC(C)=O.NNc1cccc(Cl)c1>>Cc1cc(=O)n(-c2cccc(Cl)c2)[nH]1,,CC(=O)O,,Cl,,test
US20030073836A1,COC(=O)c1c(C)cccc1-c1ccc(C(F)(F)F)cc1.O=C1CCC(=O)N1Br>>COC(=O)c1c(CBr)cccc1-c1ccc(C(F)(F)F)cc1,,ClC(Cl)(Cl)Cl,,,,test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1-c1ccc2c(c1)C(=O)CC2>>CCCC(C(=O)O)c1c(C)nc(-c2ccccc2)nc1-c1ccc2c(c1)C(=O)CC2,,CO,,[Na+].[OH-],,test
US20040097499A1,CC(CN)c1ccc(-c2ccsc2)cc1.COC(=O)Cl>>COC(=O)CC(CN)c1ccc(-c2ccsc2)cc1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20130102009A1,CC(C)(C)OC(=O)N1CCC(c2cccc(C(=O)O)c2)C1.Nc1cccc2[nH]c(-c3ccnc(Cl)c3)nc12>>CC(C)(C)OC(=O)N1CCC(c2cccc(C(=O)Nc3cccc4[nH]c(-c5ccnc(Cl)c5)nc34)c2)C1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090181942A1,COc1cccc([C@H]2S[C@H](CCOS(C)(=O)=O)c3nnc(C4CC4)n3-c3ccc(Cl)cc32)c1OC.[C-]#N>>COc1cccc([C@H]2S[C@H](CCC#N)c3nnc(C4CC4)n3-c3ccc(Cl)cc32)c1OC,,CS(C)=O,,O,,test
US20090042890A1,CCN(C(C)C)C(C)C.CCOC(=O)CN(c1ccccc1)c1nc(Cl)nc(C(=O)OCC)c1[N+](=O)[O-].CCOC(=O)CNc1ccccc1.CCOC(=O)c1nc(Cl)nc(Cl)c1[N+](=O)[O-]>>NC(=O)c1nc(-c2ccncc2)nc2c1NC(=O)CN2c1ccccc1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20030229138A1,COC(=O)c1csc(NS(C)(=O)=O)n1>>CS(=O)(=O)Nc1nc(C(=O)O)cs1,,[Na+],[OH-],,,test
US20100152265A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=c1[nH][nH]c2cc(OCc3ccccc3)ccc12>>CC(C)(C)OC(=O)n1[nH]c(=O)c2ccc(OCc3ccccc3)cc21,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20070219198A1,Clc1ccc2ccccc2n1.O=S(=O)(c1ccc(Cl)cc1)C1CCNCC1>>O=S(=O)(c1ccc(Cl)cc1)C1CCN(c2ccc3ccccc3n2)CC1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US06518257B1,CC(C)[Mg]Br.COc1ccc(C=O)cc1-c1ccc(F)cc1>>COc1ccc(C(O)C(C)C)cc1-c1ccc(F)cc1,,C1CCOC1,,[Cl-].[NH4+],,test
US05212187,CN(CCCN)CCC(c1ccc(Cl)cc1)c1ccccn1.N#CNC(=NCCCOc1cccc(CN2CCCCC2)c1)Oc1ccccc1>>CN(CCCNC(=NCCCOc1cccc(CN2CCCCC2)c1)NC#N)CCC(c1ccc(Cl)cc1)c1ccccn1,,CCOC(C)=O,,,,test
US20040132727A1,COc1cc2ncnc(Oc3ccc(N)c(Cl)c3)c2cc1OC.N[C@H]1CCN(Cc2ccccc2)C1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2ncnc(Oc3ccc(NC(=O)N[C@H]4CCN(Cc5ccccc5)C4)c(Cl)c3)c2cc1OC,,CCN(CC)CC,ClC(Cl)Cl,O=C([O-])O.[Na+],,test
US20160207889A1,COc1cccc(OC)c1-c1cc(C(=O)N[C@H](CC(=O)OC(C)(C)C)CC(C)C)nn1CC(C)C>>COc1cccc(OC)c1-c1cc(C(=O)N[C@H](CC(=O)O)CC(C)C)nn1CC(C)C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040034034A1,CC(C)(C)OC(=O)COc1cc(Cl)ccc1OCC(=O)N1CCN(Cc2ccc(F)cc2)C[C@H]1CC(N)=O>>NC(=O)C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1OCC(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US04801595,NC1CCN(CCc2c[nH]c3ccccc23)CC1.O=C(O)c1ccc2ncccc2c1>>O=C(NC1CCN(CCc2c[nH]c3ccccc23)CC1)c1ccc2ncccc2c1,,C1CCOC1,,CC(C)COC(=O)Cl,CCN(CC)CC,test
US20090099250A1,C=CCC1=C(c2ccc(O)cc2)CCCc2cc(O)ccc21>>CCCC1c2ccc(O)cc2CCCC1c1ccc(O)cc1,[Pd],CO,,,,test
US20120149734A1,CC(C)(C)OC(=O)N1Cc2nn(COCC[Si](C)(C)C)c(C(=O)O)c2C1.[NH4+]>>CC(C)(C)OC(=O)N1Cc2nn(COCC[Si](C)(C)C)c(C(N)=O)c2C1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04331669,FC(F)(F)c1cc(N=C=S)cc(C(F)(F)F)n1.Nc1ccc(C(F)(F)F)cc1>>FC(F)(F)c1ccc(NC(=S)Nc2cc(C(F)(F)F)nc(C(F)(F)F)c2)cc1,CCN(CC)CC,c1ccccc1,,,,test
US20150291593A1,Cc1ccn2cc(C(C)O)n(-c3ccccc3)c(=O)c12.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cc1ccn2cc(C(C)N=[N+]=[N-])n(-c3ccccc3)c(=O)c12,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20040162287A1,CN(C)C1(c2ccc3ccccc3c2)CCC2(CC1)OCCO2>>CN(C)C1(c2ccc3ccccc3c2)CCC(=O)CC1,,Cl,,,,test
US20110130415A1,CI.Cc1ccc([N+](=O)[O-])cc1-n1nn[nH]c1=O>>Cc1ccc([N+](=O)[O-])cc1-n1nnn(C)c1=O,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US06245922B1,Br[Mg]c1ccccc1.C[Si](C)(C)Oc1ccc(C(C#N)O[Si](C)(C)C)cc1.O>>O=C(c1ccc(O)cc1)C(O)c1ccccc1,,CCOCC,,,,test
US20150210697A1,CC(C)(C)[Si](C)(C)OCCBr.COc1ccc(CN(c2nc(Nc3cc(C#N)cc(N4CCNCC4=O)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1>>N#Cc1cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c(Cl)c(N2CCN(CCO)CC2=O)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040010037A1,CN.C[C@@H]1CN(c2ccc(C#N)c(C(F)(F)F)c2)[C@@H](C)CN1C(=O)Nc1ccnc(C(=O)O)c1>>CNC(=O)c1cc(NC(=O)N2C[C@H](C)N(c3ccc(C#N)c(C(F)(F)F)c3)C[C@H]2C)ccn1,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US08658646B2,CC(C)(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3n[nH]c4ccc(OC(F)F)cc34)nc12.N#CC1CN(CCCCl)C1>>CC(C)(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(CCCN4CC(C#N)C4)c4ccc(OC(F)F)cc34)nc12,,CN(C)C=O,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160176882A1,C=Cc1ccc(Br)cn1.CNC>>CN(C)CCc1ccc(Br)cn1,,C1CCOC1,CC(=O)O,,,test
US20150376219A1,CC(=O)OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O.Oc1ccncc1>>CC(=O)OC[C@H]1O[C@@H](n2cnc3c(-n4ccc(=O)cc4)ncnc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O,,CC#N,,CCN(C(C)C)C(C)C,,test
US06291511B1,BrBr.COc1ccccc1N>>COc1c(N)cccc1Br,,CC(=O)O,,,,test
US20100317657A1,CCI.Cc1nn(C)cc1-n1c(=O)n(C)c2cnc3ccc(Br)cc3c21>>CCn1c(=O)n(-c2cn(C)nc2C)c2c3cc(Br)ccc3ncc21,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20070244092A1,CC(C)(C)N.CC(C)(C)c1nc2cc(S(=O)(=O)Cl)ccc2n1CC1CCOCC1>>CC(C)(C)NS(=O)(=O)c1ccc2c(c1)nc(C(C)(C)C)n2CC1CCOCC1,CN(C)c1ccncc1,CC#N,,,,test
US20150111877A1,CC(=O)NC[C@H]1CN(S(=O)(=O)c2cccc(C)c2)c2cc(N)cnc2O1.O=C(Cl)c1c(F)cccc1Cl>>CC(=O)NC[C@H]1CN(S(=O)(=O)c2cccc(C)c2)c2cc(NC(=O)c3c(F)cccc3Cl)cnc2O1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20060035949A1,COC(=O)CCC/C=C\C[C@H]1[C@@H](OC2CCCCO2)C[C@@H](OC2CCCCO2)[C@@H]1/C=C/[C@H](CCc1cc(Br)c(C)s1)OC1CCCCO1>>COC(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)CCc1cc(Br)c(C)s1,,CO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US06573270B1,COCCOCN(c1c(I)c(OCCOC(C)=O)nn1C)S(=O)(=O)c1ccc(C(C)(C)C)cc1.OB(O)c1ccccc1>>COCCOCN(c1c(-c2ccccc2)c(OCCOC(C)=O)nn1C)S(=O)(=O)c1ccc(C(C)(C)C)cc1,,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090275570A1,CC(C)(C)OC(=O)NC1CCCNC1CO.O=C(Cl)OCc1ccccc1>>NC1CCCN(C(=O)OCc2ccccc2)C1CO,,ClCCl,,CCN(C(C)C)C(C)C,,test
US06136823,CN.Nc1nc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Br)c32)c(F)cc1F>>CNc1c(F)cc2c(=O)c(C(=O)O)cn(-c3nc(N)c(F)cc3F)c2c1Br,,c1ccncc1,,,,test
US20050227997A1,C=CC(C)(O)C(NS(=O)(=O)c1ccc(OCc2ccccc2)cc1)C(O[SiH2]C(C)(C)C)(c1ccccc1)c1ccccc1.C=CCBr>>C=CCN(C(C(C)(O)C=C)C(O[SiH2]C(C)(C)C)(c1ccccc1)c1ccccc1)S(=O)(=O)c1ccc(OCc2ccccc2)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05593984,NC1C(=O)N2C(C(=O)[O-])=C(CI)CS[C@H]12.c1cc2cnccn2c1>>NC1C(=O)N2C(C(=O)[O-])=C(C[n+]3ccn4cccc4c3)CS[C@H]12,,CC#N,,O,,test
US03984397,CC12CC1(C(=O)O)N1C(=O)C(NC(=O)C(OC=O)c3ccccc3)[C@H]1S2>>CC12CC1(C(=O)O)N1C(=O)C(NC(=O)C(O)c3ccccc3)[C@H]1S2,,CO,O,[K+].[OH-],,test
US05470882,Nc1cc(C(F)(F)F)ccc1Oc1cc(Cl)c(Cl)cc1S(=O)(=O)O.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1.c1ccncc1>>O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1cc(C(F)(F)F)ccc1Oc1cc(Cl)c(Cl)cc1S(=O)(=O)[O-].[NH4+],,c1ccncc1,,,,test
US20090209524A1,CCC[C@H](N)CO.COC(=O)Cc1ccc(OC)c(Cc2c(C)nc(N)nc2OS(=O)(=O)c2c(C)cc(C)cc2C)c1>>CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1cc(CC(=O)O)ccc1OC,,CCCCO,,[K+].[OH-],,test
US20110039829A1,CCOC(=O)CBr.CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(O)n(-c3cccc(OC)c3)n2)CC1>>CCOC(=O)COc1cc(C(=O)N[C@@H](CCC(=O)OC(C)(C)C)C(=O)N2CCN(C(=O)OCC)CC2)nn1-c1cccc(OC)c1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050085465A1,CC(=O)N1CCNCC1.OCCBr>>CC(=O)N1CCN(CCO)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05338853,CC1(C)CC(NC(=O)CCC(=O)NN)CC(C)(C)N1.CCOC(=O)C(=O)NC1CC(C)(C)NC(C)(C)C1>>CC1(C)CC(NC(=O)CCC(=O)NNC(=O)C(=O)NC2CC(C)(C)NC(C)(C)C2)CC(C)(C)N1,,CO,,,,test
US20090281073A1,CC(C)(C)OC(=O)NC12CNCC1C2.Cc1cc(Nc2nc(Cl)nc3ncccc23)[nH]n1>>Cc1cc(Nc2nc(N3CC4CC4(NC(=O)OC(C)(C)C)C3)nc3ncccc23)n[nH]1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20150368228A1,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.Nc1nc(Nc2cc(Cl)c(Br)c(Cl)c2)n[nH]1>>Nc1ncc(-c2c(Cl)cc(Nc3n[nH]c(N)n3)cc2Cl)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US20160068531A1,CS(=O)(=O)CCn1c(CCl)cc2cc(Cl)ccc21.O=C1Nc2ccncc2C12CC2>>CS(=O)(=O)CCn1c(CN2C(=O)C3(CC3)c3cnccc32)cc2cc(Cl)ccc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070082912A1,CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccc(Cl)cc2)c1>>Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(Cl)cc2)n1-c1cccc(C(=O)O)c1,,CCOC(C)=O,,CCO,[Na+].[OH-],test
US20120088767A1,COC(OC)N(C)C.Cc1c(Cn2c(C)nc3c(C(N)=O)cc(N4CCOCC4)cc32)cccc1C(F)(F)F.NN>>Cc1c(Cn2c(C)nc3c(-c4nc[nH]n4)cc(N4CCOCC4)cc32)cccc1C(F)(F)F,,CC(=O)O,,O,,test
US20100048568A1,Cc1cn(N)c2ccc(S(C)(=O)=O)cc12.Cc1nc(-c2cccc(F)c2)ncc1C(=O)O>>Cc1nc(-c2cccc(F)c2)ncc1C(=O)Nn1cc(C)c2cc(S(C)(=O)=O)ccc21,,CCOC(C)=O,CN(C)C=O,COc1nc(OC)nc([N+]2(C)CCOCC2)n1.[Cl-],,test
US04288436,CCCON=C(C(=O)OCC)c1csc(N)n1>>CCCON=C(C(=O)O)c1csc(N)n1,,C1CCOC1,,CO,[Na+].[OH-],test
US20160002232A1,CCOC(=O)C(Cl)C=O.CN(C)CCOc1ccnc(N)c1>>CCOC(=O)c1cnc2cc(OCCN(C)C)ccn12,,CCO,,,,test
US20070043068A1,CC(C)(C)C(=O)Cl.COc1ccccc1-c1cn(S(=O)(=O)c2ccc(C)cc2)c2ncc(-c3ccc(N)c(C(=O)N(C)C)c3)cc12.C[C@H](NC(=O)OC(C)(C)C)C(=O)O>>COc1ccccc1-c1c[nH]c2ncc(-c3ccc(NC(=O)[C@H](C)N)c(C(=O)N(C)C)c3)cc12.Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100184815A1,CC(C)(C)OC(=O)C(C)(C)Oc1ccc(CC(=O)O)cc1.CCCCCCn1c(CO)nn(Cc2ccc(C)cc2)c1=O>>CCCCCCn1c(COC(=O)Cc2ccc(OC(C)(C)C(=O)O)cc2)nn(Cc2ccc(C)cc2)c1=O,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20060135578A1,CCOP(=O)(CP(=O)(OCC)OCC)OCC.CCn1cc(C=O)c(OCc2ccc(OCc3nc(-c4ccco4)oc3C)c(OC)c2)n1>>CCOP(=O)(/C=C/c1cn(CC)nc1OCc1ccc(OCc2nc(-c3ccco3)oc2C)c(OC)c1)OCC,,O,,CN(C)C=O,[H-].[Na+],test
US20150152080A1,COC(=O)c1ccccc1CSc1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2s1>>O=C(O)c1ccccc1CSc1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2s1,,CO,,Cl,[Na+].[OH-],test
US06831106B1,COC(=O)c1cc(C)c(OS(=O)(=O)C(F)(F)F)c(C)c1.COCOc1ccc(C)c(B(O)O)c1>>COC(=O)c1cc(C)c(-c2cc(O)ccc2C)c(C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,,O=C([O-])[O-].[K+].[K+],,test
US05025031,CC(O)Cl.Oc1cccc(-n2ccnc2)c1>>OCCOc1cccc(-n2ccnc2)c1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110136763A1,COc1cc(F)c(C=O)c(OC)c1>>O=Cc1c(O)cc(O)cc1F,,ClCCl,,BrB(Br)Br,,test
US20080242706A1,C=O.Cn1cc(O)c(=O)cc1C(O)C(F)(F)F>>Cn1c(C(O)C(F)(F)F)cc(=O)c(O)c1CO,,CO,,Cl,[Na+].[OH-],test
US20120329785A1,CN1CCN(c2ccc(N)cc2)CC1.COc1ccc(Cn2cc3c(n2)c(Cl)nc2cc(F)ccc23)cc1>>CN1CCN(c2ccc(Nc3nc4cc(F)ccc4c4cn[nH]c34)cc2)CC1,C1COCCO1,CO,,Cl,,test
US20150141406A1,CCN=C=O.COc1ncc(Cl)c2c1c(-c1cn[nH]c1)nn2-c1c(F)cccc1F>>CCNC(=O)n1cc(-c2nn(-c3c(F)cccc3F)c3c(Cl)cnc(OC)c23)cn1,,C1CCOC1,,O,,test
US20080045528A1,CNC(=O)c1cc(Cl)ccn1.CSc1nc2ccc(O)cc2s1>>CNC(=O)c1cc(Oc2ccc3nc(SC)sc3c2)ccn1,,CN(C)C=O,,O,,test
US20120178926A1,CC[C@H](c1nnco1)N(c1nc(Cl)ncc1[N+](=O)[O-])C1CCCC1>>CC[C@@H]1c2nncn2-c2cnc(Cl)nc2N1C1CCCC1,[Zn],CO,,CC(=O)O,,test
US20040009983A1,Cn1cc(-c2cc3cccnc3[nH]2)c2cc(NC(=O)OC(C)(C)C)ccc21>>Cn1cc(-c2cc3cccnc3[nH]2)c2cc(N)ccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US06458781B1,CC(C)C[C@H](N)CN1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1.O=C(Cl)N1CCCCCC1>>CC(C)C[C@@H](CN1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)NC(=O)N1CCCCCC1,CN(C)c1ccncc1,c1ccccc1,,CCN(C(C)C)C(C)C,Cl,test
US20130116234A1,CCOC(=O)CC(=O)Nc1c(F)cc(Cl)cc1C#Cc1ccccc1Cl>>CCOC(=O)c1c(Cc2ccccc2Cl)c2cc(Cl)cc(F)c2[nH]c1=O,,CS(C)=O,,[H-].[Na+],,test
US06329381B1,BrBr.COCCOc1nc(N)c2ncn(Cc3ccccc3)c2n1>>Nc1nc(OCCO)nc2c1nc(Br)n2Cc1ccccc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20110224079A1,CCONC1(C#N)CCN(OC)CC1.Cc1cc(Cl)cc(C)c1CC(=O)Cl>>CCON(C(=O)Cc1c(C)cc(Cl)cc1C)C1(C#N)CCN(OC)CC1,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20140024650A1,CCOC(=O)[C@@H]1COCC[C@H]1NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H]1CCOC[C@H]1CO,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20080039506A1,CC(=O)OCCCS(=O)(=O)NC(=O)c1ccc(-c2ccc(CCN(C[C@H](O)c3cccc(Cl)c3)C(=O)OC(C)(C)C)cc2)cc1OC1CCCCC1.Cl>>Cl.O=C(NS(=O)(=O)CCCO)c1ccc(-c2ccc(CCNC[C@H](O)c3cccc(Cl)c3)cc2)cc1OC1CCCCC1,,CO,Cl,,,test
US20020147214A1,N#C[Cu].O=c1[nH]cnc2ccc(I)cc12>>N#Cc1ccc2nc[nH]c(=O)c2c1,,CN1CCCC1=O,,,,test
US20140243537A1,CC(C)(C)[Si](C)(C)Cl.O/C=C\CCO>>CC(C)(C)[Si](C)(C)OC/C=C\CO,,ClCCl,,c1c[nH]cn1,,test
US04565659,C1CO1.CCCCCCCCCCCCCCCCCCNCc1ccccc1>>CCCCCCCCCCCCCCCCCCN(CCO)Cc1ccccc1,,CO,,O=C=O,,test
US20100160340A1,CC(C)(C)OC(=O)N1CCC(O)CC1.O=[N+]([O-])c1ccc(F)cn1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc([N+](=O)[O-])nc2)CC1,,CC(=O)N(C)C,,O,CC(C)(C)[O-].[K+],test
US06204294B1,C=CCBr.N#Cc1ccc([N+](=O)[O-])c(O)c1>>C=CCOc1cc(C#N)ccc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04638012,NCC(=O)O.O=C(Cl)c1ccc(-c2ccccc2)cc1>>O=C(O)CNC(=O)c1ccc(-c2ccccc2)cc1,,C1CCOC1,,CCOCC,[Na+].[OH-],test
US20150322043A1,CCOC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1>>O=C(O)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1,,O,,Cl,[Na+].[OH-],test
US20110195961A1,CC(C)(C)[Si](C)(C)OCCCCC1CO1.Nc1ccc2c(c1)NC(=O)CS2>>CC(C)(C)[Si](C)(C)OCCCCC(O)CNc1ccc2c(c1)NC(=O)CS2,,CCO,O,,,test
US20050148627A1,CCOC(=O)C1=Cc2cc(OC(F)(F)F)cc(C(C)=O)c2OC1C(F)(F)F.C[Mg]Br>>CCOC(=O)C1=Cc2cc(OC(F)(F)F)cc(C(C)(C)O)c2OC1C(F)(F)F,,C1CCOC1,,,,test
US20050038035A1,Cc1ccc(C(=O)Cl)c(-c2ccc(C(F)(F)F)cc2)c1.Nc1ccc(C(=O)NCCc2ccccn2)cc1>>Cc1ccc(C(=O)Nc2ccc(C(=O)NCCc3ccccn3)cc2)c(-c2ccc(C(F)(F)F)cc2)c1,,C1CCOC1,O,CCN(CC)CC,CCOC(C)=O,test
US20070021346A1,Cc1ccc(Br)nn1.O=C1CCC(=O)N1Br>>BrCc1ccc(Br)nn1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20070259886A1,CC(C)c1cc(C(=O)N2Cc3ccc(OCCCNC(=O)OC(C)(C)C)cc3C2)c(O)cc1O>>CC(C)c1cc(C(=O)N2Cc3ccc(OCCCN)cc3C2)c(O)cc1O,,CCOC(C)=O,,Cl,,test
US20110301175A1,Cc1ccc(Nc2ncc(-c3ccc(OC(F)F)cc3)cn2)cc1NC(=O)N1CCN(Cc2ccccc2)C2(CC2)C1>>Cc1ccc(Nc2ncc(-c3ccc(OC(F)F)cc3)cn2)cc1NC(=O)N1CCNC2(CC2)C1,[Pd],CO,,[H][H],,test
US04753934,CCOC(=O)CP(=O)(OCC)OCC.Nc1c(Cl)cc(C(=O)c2ccc(Cl)cc2)cc1Cl>>CCOC(=O)C=C(c1ccc(Cl)cc1)c1cc(Cl)c(N)c(Cl)c1,,COCCOC,,[H-].[Na+],,test
US20120046267A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(-c2cnn([C@@H]3CC[C@@H](O[Si](C)(C)C(C)(C)C)CC3)c2)c2ccoc12.COB(OC)OC>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(-c2cnn([C@@H]3CC[C@@H](O[Si](C)(C)C(C)(C)C)CC3)c2)c2cc(B(O)O)oc12,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20030181496A1,COS(=O)(=O)OC.Nc1ccc(Cl)cc1C(=O)O>>COC(=O)c1cc(Cl)ccc1N,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04298741,COS(=O)(=O)OC.[N-]=[N+]=NC1C(=O)N2C(C(=O)OCc3ccccc3)C(=O)CC12>>COC1=C(C(=O)OCc2ccccc2)N2C(=O)C(N=[N+]=[N-])C2C1,,CC(C)=O,CCOCC,O=C([O-])[O-].[K+].[K+],,test
US04028386,CC(C)=CCCO.CC1(CCCBr)OCCO1>>CC(C)=CCCOCCCC1(C)OCCO1,,CN(C)C=O,,O,[H-].[Na+],test
US20090318518A1,FC(F)(F)c1ccc(CBr)cc1.Fc1cc(Br)c2[nH]ccc2c1>>Fc1cc(Br)c2c(ccn2Cc2ccc(C(F)(F)F)cc2)c1,,CN(C)C=O,,[H-].[Na+],,test
US20030199689A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCCc1ccc(Cl)cc1>>Cc1ccc(S(=O)(=O)OCCc2ccc(Cl)cc2)cc1,,c1ccncc1,,,,test
US20110237620A1,CN(c1cccc(N)c1)c1ccc2nc(NC(=O)C3CC3)sc2n1.O=C=Nc1ccc(OC(F)(F)F)cc1>>CN(c1cccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)c1)c1ccc2nc(NC(=O)C3CC3)sc2n1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20100137299A1,Cn1c(=O)oc2ccc(O[Si](C)(C)C(C)(C)C)cc21>>Cn1c(=O)oc2ccc(O)cc21,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20030229228A1,CCS(=O)(=O)N[C@H](C(=O)O)C(C)C.COc1cc(CCN)cc(Br)c1OCc1ccccc1>>CCS(=O)(=O)N[C@H](C(=O)NCCc1cc(Br)c(OCc2ccccc2)c(OC)c1)C(C)C,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20020068737A1,O=C1NC(c2ccc(F)c(F)c2)CO1>>NC(CO)c1ccc(F)c(F)c1,,CCO,,O,[K+].[OH-],test
US20050176772A1,COC(=O)[C@@H]1CN(Cc2ccccc2)C[C@H]1c1ccc(F)cc1F>>COC(=O)[C@@H]1CNC[C@H]1c1ccc(F)cc1F,[Pd],CCO,,[H][H],,test
US20070031514A1,COC1OC(=O)c2cccc([N+](=O)[O-])c21>>O=C1OC(O)c2c1cccc2[N+](=O)[O-],,O,,Cl,,test
US20110065706A1,C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1c1ncc(OCc2ccc(CS(C)(=O)=O)cc2F)cn1.O=C(Oc1c(F)c(F)c(F)c(F)c1F)OC1(C(F)(F)F)COC1>>C[C@@H]1CN(C(=O)OC2(C(F)(F)F)COC2)CCN1c1ncc(OCc2ccc(CS(C)(=O)=O)cc2F)cn1,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,Cl,test
US20040127538A1,O=C1CCC(=O)N1Br.O=[N+]([O-])c1ccc2[nH]ncc2c1>>O=[N+]([O-])c1ccc2[nH]nc(Br)c2c1,CC(C)(C#N)N=NC(C)(C)C#N,ClC(Cl)(Cl)Cl,,,,test
US20080051404A1,COc1ccc(C2OC[C@@H]3C[C@@H](N4C(=O)c5ccccc5C4=O)C[C@@H]3O2)cc1>>COc1ccc(C2OC[C@@H]3C[C@@H](N)C[C@@H]3O2)cc1,,CCO,,NN,,test
US20020103230A1,CCOC(=O)Cc1nc2cc(N3CCN(C)CC3)ccc2[nH]1.N#Cc1ncccc1N>>CN1CCN(c2ccc3[nH]c(-c4c(N)c5ncccc5[nH]c4=O)nc3c2)CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20070249587A1,CC(C)(C)OC(=O)N1CCC(c2ccccc2S(=O)(=O)[O-])CC1.CCOC(=O)CC(=O)OCC>>CCOC(=O)C(C(=O)OCC)C1CCN(C(=O)OC(C)(C)C)CC1,,CCO,,C,C[O-].[Na+],test
US20070112211A1,CC1(C)OC[C@@H](CO)O1.CCCCCCCCCCCCCCCCBr>>CCCCCCCCCCCCCCCCOCC(O)CO,,Cc1ccccc1,,O,[K+].[OH-],test
US20100190775A1,CCN.CCNc1nc(S(C)(=O)=O)nc2c1C(=O)N(c1cccc(-c3nn(C)c(=O)o3)c1)C[C@@H]1CCCN21>>CCNc1nc(NCC)c2c(n1)N1CCC[C@H]1CN(c1cccc(-c3nn(C)c(=O)o3)c1)C2=O,,C1CCOC1,,,,test
US05719141,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H](N)CC1(COCc2ccccc2)CC1>>COC(=O)[C@H](CC1(COCc2ccccc2)CC1)NC(=O)OC(C)(C)C,,C1CCOC1,,,,test
US20110136763A1,CC(C)I.CCOC(=O)CC1OB(O)c2cc(Oc3cnccn3)cc(O)c21>>CCOC(=O)CC1OB(O)c2cc(Oc3cnccn3)cc(OC(C)C)c21,,CN(C)C=O,,[H-].[Na+],,test
US20140080808A1,Cc1cnc(-c2ccc(C3(c4nnc5n4CCS[C@@](C)(CO[Si](C)(C)C(C)(C)C)C5)CC3)cc2)nc1>>Cc1cnc(-c2ccc(C3(c4nnc5n4CCS[C@@](C)(CO)C5)CC3)cc2)nc1,,C1COCCO1,CO,Cl,,test
US20160108039A1,C[C@@H]1COC(C)(CCO)C(=O)N1Cc1ccccc1>>C[C@@H]1COC(C)(CCO)CN1Cc1ccccc1,,C1CCOC1,,CO,,test
US20150045323A1,CC(C)(C)S(=O)(=O)c1cc2c(Nc3ccc4scnc4c3)ncnc2cc1OCCO.CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)O>>CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)OCCOc1cc2ncnc(Nc3ccc4scnc4c3)c2cc1S(=O)(=O)C(C)(C)C,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160145251A1,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C(C(=O)Nc2ccc(Cl)cc2)C1>>O=C(Nc1ccc(Cl)cc1)C1CNCCN1C(=O)OCc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130129677A1,CC(=O)OC(C)=O.Nc1c(C(=O)Nc2nnc(-c3ccccc3)s2)sc2nc3c(cc12)CCCCC3>>CC(=O)Nc1c(C(=O)Nc2nnc(-c3ccccc3)s2)sc2nc3c(cc12)CCCCC3,,CN(C)C=O,,ClCCl,c1ccncc1,test
US20100093811A1,COC(=O)N[C@H](C(=O)N[C@H](CCC[C@@H](CO)N(CCC(C)C)S(=O)(=O)c1ccc(C(=O)OC)c(F)c1)C1CC1)C(c1ccc(F)cc1)c1ccc(F)cc1>>COC(=O)N[C@H](C(=O)N[C@H](CCC[C@@H](CO)N(CCC(C)C)S(=O)(=O)c1ccc(CO)c(F)c1)C1CC1)C(c1ccc(F)cc1)c1ccc(F)cc1,,C1CCOC1,,[BH4-].[Li+],,test
US04594347,C1CNCCN1.CC1Cc2c(F)c(F)c(N)c3c(=O)c(C(=O)O)cn1c23>>CC1Cc2c(N3CCNCC3)c(F)c(N)c3c(=O)c(C(=O)O)cn1c23,,CN1CCCC1=O,,,,test
US20150232435A1,Cc1nc(N2CCN(CCCCN)CC2)cc(C(C)(C)C)n1.Clc1ccc2[nH]c3c(c2c1)CNCC3.O=C(n1ccnc1)n1ccnc1>>Cc1nc(N2CCN(CCCCNC(=O)N3CCc4[nH]c5ccc(Cl)cc5c4C3)CC2)cc(C(C)(C)C)n1,,CO,ClC(Cl)Cl,,,test
US20100121052A1,Fc1c(Br)ccc2nc(Cl)ncc12.Nc1ccc(N2CCOCC2)cc1>>Fc1c(Br)ccc2nc(Nc3ccc(N4CCOCC4)cc3)ncc12,,CC(C)O,,,,test
US20150141400A1,CC(C)(C)OC(=O)NC[C@H]1CCCNC1.CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(C=O)c(C(F)(F)F)cc2c1=O>>CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(CN3CCC[C@H](CNC(=O)OC(C)(C)C)C3)c(C(F)(F)F)cc2c1=O,,ClC(Cl)Cl,,,,test
US20150005232A1,COC(=O)CBr.O=c1ccc(Br)c[nH]1>>COC(=O)Cn1cc(Br)ccc1=O,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070185101A1,CC(=O)O[C@@H]1C(C)=C[C@H]2[C@H](C(C)=C(F)F)CC[C@H](C)[C@@]2(O)[C@@H]1OC(=O)[C@@H]1C[C@@]2(OC(=O)OC(C)(C)C)c3cccc(Cl)c3N(C)O[C@H]2N1C(=O)OC(C)(C)C>>CC(=O)O[C@@H]1C(C)=C[C@H]2[C@H](C(C)=C(F)F)CC[C@@H](C)[C@]2(O)[C@H]1OC(=O)[C@@H]1C[C@@]2(O)c3cccc(Cl)c3N(C)O[C@H]2N1,,CCOC(C)=O,,Cl,,test
US20030208018A1,C=C(C)C(=O)OC.C=C(C)C(=O)OCC1CO1.C=CC(=O)OCCO.C=CC(=O)OCCS(=O)(=O)c1ccc(C)cc1>>C=C(C)C(=O)OC.C=C(C)C(=O)OCC1CO1.C=CC(=O)OCCO.C=CC(=O)OCCS(=O)(=O)c1ccc(C)cc1,,C1CCOC1,,,,test
US20100273779A1,CCOC(=O)c1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1.Cc1ccccn1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(C(=O)Cc3ccccn3)cc2)CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20020173503A1,CC(C)(C)OC(=O)N1CC[C@H]2[C@@H](C1)c1cc(Br)cc3c1N2CCSC3.COc1ccc(B(O)O)c(C)c1>>COc1ccc(-c2cc3c4c(c2)[C@@H]2CNCC[C@@H]2N4CCSC3)c(C)c1,,CCOC(C)=O,COCCOC,,,test
US20130035325A1,Nc1cccc(CO)c1.O=C(CBr)c1ccc(Cl)cc1>>O=C(CNc1cccc(CO)c1)c1ccc(Cl)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20040023947A1,CCOC(=O)C1=CNCCc2c1[nH]c1ccccc21.CI>>CCOC(=O)C1=CN(C)CCc2c1[nH]c1ccccc21,,CN(C)C=O,,O,[H-].[Na+],test
US20070072853A1,CC(C)(C)C(=O)Cl.COC(=O)Nc1ccc(NCCN2CCCCC2)c(N)c1>>COC(=O)Nc1ccc2c(c1)nc(C(C)(C)C)n2CCN1CCCCC1,CN(C)c1ccncc1,ClCCl,,,,test
US20040259888A1,CN1CCNCC1.Clc1ncnc2oc(-c3ccc(Br)cc3)c(-c3ccccc3)c12>>CN1CCN(c2ncnc3oc(-c4ccc(Br)cc4)c(-c4ccccc4)c23)CC1,,C1CCOC1,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US20140213599A1,C[C@@H](CO)N(C)c1cc(Cl)nc(=O)[nH]1>>C[C@H]1Cn2c(cc(Cl)nc2=O)N1C,,C1CCOC1,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20150065464A1,Cc1nc(Oc2cccc(CO)c2)ccc1C(F)(F)F.O=S(Cl)Cl>>Cc1nc(Oc2cccc(CCl)c2)ccc1C(F)(F)F,,ClCCl,,,,test
US20140127709A1,CCCCCCCCCCCCCCCCCC(=O)O.O=C1CCC(=O)N1O>>CCCCCCCCCCCCCCCCCC(=O)ON1C(=O)CCC1=O,,CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20110319393A1,CC(C)(C)OC(=O)N1CCC(N)CC1.O=S(=O)(c1ccc(F)cc1)c1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCC(Nc2ccc(S(=O)(=O)c3ccc(F)cc3)cc2)CC1,,CS(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20140275071A1,Cn1c(=O)n(CCCOC2CCCCO2)c(=O)c2c1nc(Br)n2Cc1ccc(Cl)cc1.OCCOC1CCCCC1>>Cn1c(=O)n(CCCOC2CCCCO2)c(=O)c2c1nc(OCCOC1CCCCC1)n2Cc1ccc(Cl)cc1,,C1CCOC1,,[H-].[Na+],,test
US04839355,CCOC(=O)c1cn2c3c(c(N=[N+]=[N-])c(F)cc3c1=O)OC[C@@H]2C>>CCOC(=O)c1cn2c3c(c(N)c(F)cc3c1=O)OC[C@@H]2C,[Pd],CN(C)C=O,,CCO,,test
US07241317B2,O=[N+]([O-])c1ccccc1F.OCCN1CCCNCC1>>O=[N+]([O-])c1ccc(N2CCCN(CCO)CC2)cc1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20120022064A1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.O=C1CCc2cc(O)ccc2N1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc3c(c2)CCC(=O)N3)CC1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100144987A1,CC(=O)CCCl.O=CNc1ccccc1.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>Cc1sc[n+](-c2ccccc2)c1C.[Cl-],,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20160122342A1,CCN(c1cccc2c1CC=CCC(C)c1cc(C)[nH]c(=O)c1CNC2=O)C1CCOCC1>>CCN(c1cccc2c1CCCCC(C)c1cc(C)[nH]c(=O)c1CNC2=O)C1CCOCC1,[Pd],CO,,,,test
US20110301142A1,CCOC(=O)c1cn[nH]c1.Cc1noc(-c2ccc(CCl)cc2)c1NC(=O)OC(C)c1ccccc1Cl>>CCOC(=O)c1cnn(Cc2ccc(-c3onc(C)c3NC(=O)OC(C)c3ccccc3Cl)cc2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050222170A1,N#Cc1ccccc1CBr.Nc1nc(-c2n[nH]c3ncccc23)ncc1-c1ccncc1>>N#Cc1ccccc1Cn1nc(-c2ncc(-c3ccncc3)c(N)n2)c2cccnc21,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20080280924A1,CC(C)(C)NS(=O)(=O)c1ccc(-c2cccc(-c3nc(-c4ccc(C(F)(F)F)nc4)cc(C(F)(F)F)n3)c2)s1>>NS(=O)(=O)c1ccc(-c2cccc(-c3nc(-c4ccc(C(F)(F)F)nc4)cc(C(F)(F)F)n3)c2)s1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090281127A1,CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(N[C@@H]4CCNC4)nc32)[C@H](O)[C@@H]1O.O=C(NC1CCN(c2ccccn2)CC1)n1ccnc1.O=C(O)C(F)(F)F>>CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(N[C@@H]4CCN(C(=O)NC5CCN(c6ccccn6)CC5)C4)nc32)[C@H](O)[C@@H]1O.O=C(O)C(F)(F)F,,CC(C)O,ClCCl,,,test
US20040009998A1,O=C(CCBr)c1ccc(Br)cc1>>OC(CCBr)c1ccc(Br)cc1,,CO,,Cl,[BH4-].[Na+],test
US20090274655A1,CC(C)N(C(=O)[C@@H]1CC[C@@H](C)CC1)c1cc(-c2ccc(NC(=O)c3cscn3)cc2)sc1C(=O)O.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>CNC[C@H](O)[C@@H](OC(=O)c1sc(-c2ccc(NC(=O)c3cscn3)cc2)cc1N(C(=O)[C@H]1CC[C@H](C)CC1)C(C)C)[C@H](O)[C@H](O)CO,,CC(C)=O,,,,test
US20120101127A1,CC1(C)CC(c2cccc(N)c2)Nc2ccc(C(F)(F)F)cc21.O=S(=O)(Cl)c1ccccc1>>CC1(C)CC(c2cccc(NS(=O)(=O)c3ccccc3)c2)Nc2ccc(C(F)(F)F)cc21,,ClCCl,,c1ccncc1,,test
US20150065482A1,COC(=O)c1nn(-c2cc(C#C[C@]3(O)CCN(C)C3=O)cc(OC(F)F)c2)c2ncccc12.N>>CN1CC[C@@](O)(C#Cc2cc(OC(F)F)cc(-n3nc(C(N)=O)c4cccnc43)c2)C1=O,,CO,,,,test
US20130072467A1,NCc1ncco1.O=C1NC(=S)CS1>>O=C1N=C(NCc2ncco2)CS1,,CCO,,CCN(CC)CC,Cl,test
US20160016948A1,CC(C)n1c(CCl)nc2cnc(Cl)cc21.CCOCCO>>CCOCCOCc1nc2cnc(Cl)cc2n1C(C)C,,C1CCOC1,O,[H-].[Na+],,test
US20060052599A1,Cc1ccc(CN2CC[C@@H](NC(=O)OC(C)(C)C)C2)cc1>>Cc1ccc(CN2CC[C@@H](N)C2)cc1,,CCOC(C)=O,,Cl,,test
US20050282891A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1)C(=O)O.C[C@@H](O)COC(=O)c1ccccc1>>C[C@H](COC(=O)c1ccccc1)OC(=O)[C@H](Cc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1)NC(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20110288065A1,CC(=O)OC(C)=O.C[C@H](Nc1nc(Nc2cnccn2)cc(N2CC(CN)C2)n1)c1ccc(F)cc1>>CC(=O)NCC1CN(c2cc(Nc3cnccn3)nc(N[C@@H](C)c3ccc(F)cc3)n2)C1,,ClCCCl,,c1ccncc1,,test
US20030139441A1,CS(=O)(=O)Cl.Cc1nc2c(N)nc3ccccc3c2n1CCOCCN>>Cc1nc2c(N)nc3ccccc3c2n1CCOCCNS(C)(=O)=O,,CN1CCCC1=O,,CCN(CC)CC,O,test
US04950674,COc1cc(C(C)=O)ccc1O.ClCCCCBr>>COc1cc(C(C)=O)ccc1OCCCCCl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US08829007B2,Fc1cnc(-c2c[nH]c3ncc(Cl)cc23)nc1N[C@H]1CCCNC1.Fc1cnc(-c2c[nH]c3ncc(Cl)cc23)nc1N[C@H]1CCCNC1.O=C(Cl)C1CCC1>>O=CC1CC(N2CCCCC2Nc2nc(-c3c[nH]c4ncc(Cl)cc34)ncc2F)C1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,Cl,test
US04990517,CO[C@@H]1CN(Cc2ccccc2)C[C@H]1NC(=O)OC(C)(C)C>>CO[C@@H]1CNC[C@H]1NC(=O)OC(C)(C)C,[Pd],CO,,,,test
US20020188125A1,CCCCCCCCCCCCCCCCCC(=O)Cl.CCCCCCCCCCCCCCCCCC(=O)OCC[C@@H](CO)Cn1cnc2c(=O)[nH]c(N)nc21.CN(C)C=O.CN(C)c1ccncc1.c1ccncc1>>CCCCCCCCCCCCCCCCCC(=O)OCC[C@@H](COC(=O)[C@@H](N)C(C)C)Cn1cnc2c(=O)[nH]c(N)nc21,CN(C)c1ccncc1,,,,,test
US20120270857A1,COC(=O)c1cccc2cnn(CCO)c12>>COC(=O)c1cccc2cnn(CC=O)c12,,ClCCl,,CS(C)=O,O=C(Cl)C(=O)Cl,test
US20110098324A1,CC(C)N.CCOC(=O)CNC(=O)c1c(O)c(C(=O)OC)c(O)n(Cc2ccccc2C(F)(F)F)c1=O>>CC(C)NC(=O)c1c(O)c(C(=O)NCC(=O)O)c(=O)n(Cc2ccccc2C(F)(F)F)c1O,,ClC(Cl)Cl,,,,test
US20130203745A1,C=C(C)C(=O)OC(C)(C)C.Cc1cccc(Oc2ccc(C3CNCCO3)cc2)c1C>>Cc1cccc(Oc2ccc(C3CN(CC(C)C(=O)OC(C)(C)C)CCO3)cc2)c1C,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20020103229A1,O=C(N[C@H]1CCc2ccccc21)c1cccc(-c2nn(C3CCCCO3)c3ccc(-c4ncn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc23)c1>>O=C(N[C@H]1CCc2ccccc21)c1cccc(-c2n[nH]c3ccc(-c4ncn[nH]4)cc23)c1,,C1COCCO1,,Cl,O=C([O-])O.[Na+],test
US20090281103A1,Cc1cccc(C=O)c1C.NC1CC1>>Cc1cccc(CNC2CC2)c1C,,CO,,[BH4-].[Na+],,test
US05908858,CC(=O)NS(=O)(=O)c1ccc(N)cc1.COc1ccc(C(=O)CC(C)C=O)cc1>>COc1ccc(-c2cc(C)cn2-c2ccc(S(=O)(=O)NC(C)=O)cc2)cc1,,CC(=O)O,ClC(Cl)Cl,O=C([O-])O.[Na+],,test
US20110166182A1,COc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(C(N)=O)s3)ccc2c1.Cl>>COc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(C#N)s3)ccc2c1.Cl,,ClCCl,,O=P(Cl)(Cl)Cl,,test
US20050032838A1,CSc1cc(O)ccc1Cl.O=C(N[C@@H]1CC[C@@H](O)CC1)c1cc(F)cnc1Cl>>CSc1cc(Oc2ncc(F)cc2C(=O)N[C@@H]2CC[C@@H](O)CC2)ccc1Cl,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090318421A1,COC(=O)c1c(OCc2ccccc2)c(=O)c(C(=O)NCc2ccc(F)cc2)cn1CC=O.NCC[C@@H]1CCCN1>>O=C(NCc1ccc(F)cc1)c1cn2c(c(OCc3ccccc3)c1=O)C(=O)N1CC[C@@H]3CCCN3[C@@H]1C2,,ClCCl,,CC(=O)O,,test
US06281363B1,CC(C)C[C@@H](C(=O)NN1CC(=O)NC1=O)[C@H](C/C=C/c1ccccc1)C(=O)NO>>CC(C)C[C@@H](C(=O)NN1CC(=O)NC1=O)[C@H](CCCC1CCCCC1)C(=O)NO,O=[Pt]=O,CC(=O)O,,,,test
US20100261698A1,CCI.N#CCc1ccccc1NC(=O)c1cccnc1>>CCn1c(-c2cccnc2)c(C#N)c2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05834506,CC(C)(C)OC(=O)N1CCN(CCOc2ccc(C(=O)CCc3ccccc3)cc2)CC1.COC(=O)CC(C)=O>>CC(C)(C)OC(=O)N1CCN(CCOc2ccccc2C2(CCc3ccccc3)CC(O)=CC(=O)O2)CC1,,C1CCOC1,,[Li]CCCC,[H-].[Na+],test
US05155130,C=CC=O.COc1ccc(O)c(C=O)c1>>COc1ccc2c(c1)C=C(C=O)CO2,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US03969402,CC(C(=O)O)c1ccc(-c2ccc(F)cc2F)c(O)c1.N>>CC(C(N)=O)c1ccc(-c2ccc(F)cc2F)c(O)c1,,c1ccccc1,,O=S(Cl)Cl,,test
US20140179670A1,CCOC(C)=O.Cc1c(-c2c(Br)cnn2-c2ccc(C#N)cc2)c(=O)n(C)c(=O)n1-c1cccc(C(F)(F)F)c1>>Cc1c(-c2c(C(=O)O)cnn2-c2ccc(C#N)cc2)c(=O)n(C)c(=O)n1-c1cccc(C(F)(F)F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,CCN(C(C)C)C(C)C,O,test
US20020183318A1,C#CCBr.Cc1c(-c2ccccc2)oc2cc(O)ccc2c1=O>>CC#COc1ccc2c(=O)c(C)c(-c3ccccc3)oc2c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050009845A1,C[Si](C)(C)C#CC1=CC2C(=NC=NC2Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)S1>>C#Cc1cc2c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)ncnc2s1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120142653A1,C=C(C)[C@@H]1CC[C@]2(C(=O)NCCNCc3ccccc3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.COC(=O)CBr>>C=C(C)[C@@H]1CC[C@]2(C(=O)NCCN(CC(=O)OC)Cc3ccccc3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1COCCO1,CC#N,O=C([O-])[O-].[K+].[K+],,test
US20070225505A1,CCOC(=O)C1C(=O)N(S(=O)(=O)c2ccc(C)cc2)C2CCCCC12>>Cc1ccc(S(=O)(=O)N2C(=O)CC3CCCCC32)cc1,,CN(C)C=O,,O,[Cl-].[Na+],test
US20050261372A1,CC(=O)c1ccc(OC(=O)[C@H]2COC(C)(C)N2C(=O)OC(C)(C)C)cc1.O=C(O)C(F)(F)F>>CC(=O)c1ccc(OC(=O)[C@H](N)CO)cc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20150210666A1,CCCCCCCC(F)(F)CCCCCC/C=C/[C@H](C(=O)N1C(=O)SC(c2ccccc2)(c2ccccc2)[C@@H]1C(C)C)[C@@](O)(CCOC)C(=O)OC(C)(C)C.CCCCOc1ccc(C[C@H](N)C(=O)OC)cc1>>CCCCCCCC(F)(F)CCCCCC/C=C/[C@H](C(=O)N[C@@H](Cc1ccc(OCCCC)cc1)C(=O)OC)[C@@](O)(CCOC)C(=O)OC(C)(C)C,,ClCCl,,,,test
US05411979,COC(=O)C(N)CO.O=C(Cl)c1c(F)cccc1F>>COC(=O)[C@H](CO)NC(=O)c1c(F)cccc1F,,c1ccncc1,,Cl,,test
US20150353499A1,Cc1c(Cl)nc2ccccc2c1C(=O)Cl>>Cc1c(Cl)nc2ccccc2c1CO,,O,,C1CCOC1,[BH4-].[Na+],test
US20130090323A1,COc1ccc(B(O)O)cn1.Nc1cc(Cl)ncc1Br>>COc1ccc(-c2cnc(Cl)cc2N)cn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20100310512A1,COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(N3CCN(c4ccc(-c5cnc(C6CCCN6C(=O)C(NC(=O)OC)C(C)C)n5COCC[Si](C)(C)C)cc4)CC3)cc2)n1COCC[Si](C)(C)C)C(C)C>>COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(N3CCN(c4ccc(-c5cnc(C6CCCN6C(=O)C(NC(=O)OC)C(C)C)[nH]5)cc4)CC3)cc2)[nH]1)C(C)C,,O=C(O)C(F)(F)F,,,,test
US04990521,CCOC(=O)N1CC[C@@H](N=[N+]=[N-])[C@H](OC)C1>>CCOC(=O)N1CC[C@@H](N)[C@H](OC)C1,[Pd],CO,,[H][H],,test
US20070082880A1,N#Cc1cnc2sc(-c3ccccc3)cc2c1Cl.Nc1ccc2cc[nH]c2c1>>Cl.N#Cc1cnc2sc(-c3ccccc3)cc2c1Nc1ccc2cc[nH]c2c1,,CCO,,,,test
US20100113547A1,C=CCOCC1(c2cccc(C#N)c2)NC(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C1=O.CI>>C=CCOCC1(c2cccc(C#N)c2)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)N1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160016908A1,CC(=O)N1c2ccccc2[C@H](Nc2ccccc2)[C@@H](C)[C@@H]1CO[Si](C)(C)C(C)(C)C>>CC(=O)N1c2ccccc2[C@H](Nc2ccccc2)[C@@H](C)[C@@H]1CO,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150087646A1,CC(C)(C)C(=O)Cl.NCc1ccc(Cl)c(N)c1>>CC(C)(C)C(=O)NCc1ccc(Cl)c(N)c1,,C1CCOC1,,,,test
US20130224186A1,OCc1nc(-c2cc(F)ccc2F)sc1Cc1ccccc1>>O=Cc1nc(-c2cc(F)ccc2F)sc1Cc1ccccc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20100093724A1,CI.O=C(NCc1cccc(C(F)(F)F)c1)c1cncc2c1cnn2-c1ccc(F)cc1>>C[n+]1cc(C(=O)NCc2cccc(C(F)(F)F)c2)c2cnn(-c3ccc(F)cc3)c2c1.[I-],,C1CCOC1,,,,test
US20100197678A1,Brc1csc(N2CCOCC2)n1.CON(C)C(=O)C(F)(F)F>>O=C(c1csc(N2CCOCC2)n1)C(F)(F)F,,C1CCOC1,CCOCC,[Li]CCCC,,test
US20040157866A1,C=Cc1nccs1.O=C(Nc1ccc2c(c1)CCN2)c1ccccc1-c1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc2c(c1)CCN2CCc1nccs1)c1ccccc1-c1ccc(C(F)(F)F)cc1,,COCCO,,CS(=O)(=O)O,,test
US04442126,CCC(=O)NC1CCc2cc(OC)ccc2C1.O=[N+]([O-])O>>CCC(=O)NC1CCc2c(ccc(OC)c2[N+](=O)[O-])C1,,CCOCC,O,O=C(O)C(F)(F)F,,test
US20100137308A1,CNC.COc1cc(C(=O)O)cc([N+](=O)[O-])c1>>COc1cc(C(=O)N(C)C)cc([N+](=O)[O-])c1,,ClCCl,,,,test
US05919950,CCC(Br)CC.COC(=O)c1ccc(O)cc1O>>CCC(CC)Oc1ccc(C(=O)OC)c(O)c1,,CCC(C)=O,,[I-].[K+],,test
US20040049070A1,CCC(C)OC(=O)Cl.O=C(O)COc1ccccc1>>CCC(C)OC(=O)OC(=O)COc1ccccc1,,CCOCC,,[Na+].[OH-],,test
US05550134,CI.C[C@]12CCC(=O)N[C@@H]1CCc1cc(-c3ccc4c(c3)Cc3ccccc3-4)ccc12>>CN1C(=O)CC[C@]2(C)c3ccc(-c4ccc5c(c4)Cc4ccccc4-5)cc3CC[C@@H]12,,CCOC(C)=O,,CC(C)(C)O,CC(C)(C)[O-].[K+],test
US20100267696A1,O=C(c1csc(Br)c1)N1CCC[C@@H]2CCCC[C@@H]21.O=C1CNCCN1>>O=C1CNCCN1c1cc(C(=O)N2CCC[C@@H]3CCCC[C@@H]32)cs1,[Cu]I,COCCOC,ClCCl,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US20020072514A1,NO.O=C1CCCOc2ccccc21>>ON=C1CCCOc2ccccc21,,CCO,c1ccncc1,Cl,,test
US20120077828A1,CC(C)(C)OC(=O)N1CC=C(c2cnc(N)c3c(-c4ccc5c(c4)CCN5C(=O)Cc4ccccc4)csc23)CC1>>Nc1ncc(C2=CCNCC2)c2scc(-c3ccc4c(c3)CCN4C(=O)Cc3ccccc3)c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070078169A1,CN(C)C1CC=C(c2cccc(NC(=O)c3ccc(F)cc3)c2F)CC1.Cl>>CN(C)C1CC=C(c2cccc(NC(=O)c3ccc(F)cc3)c2F)CC1.Cl,,CCOCC,ClCCl,,,test
US20150232445A1,CC(=O)N1c2ccc(-c3cnn(C4CCN(C(=O)OC(C)(C)C)CC4)c3)c(O)c2CC[C@@H]1C.O=S(=O)(N(c1ccc(Cl)cn1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(=O)N1c2ccc(-c3cnn(C4CCN(C(=O)OC(C)(C)C)CC4)c3)c(OS(=O)(=O)C(F)(F)F)c2CC[C@@H]1C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20040224996A1,C=O.CCOCCc1csc(NS(=O)(=O)c2cccc(Cl)c2C)n1.CNC>>CCOCCc1nc(NS(=O)(=O)c2cccc(Cl)c2C)sc1CN(C)C,,CC(=O)O,,Cl,,test
US05521147,CI.O=c1cc(C(F)(F)F)[nH]c(=O)n1-c1c(F)cc(Cl)c2c1OCCC2>>Cn1c(C(F)(F)F)cc(=O)n(-c2c(F)cc(Cl)c3c2OCCC3)c1=O,,CCCCCC,CN(C)C=O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090239854A1,C=C(C)c1ccc(C)nc1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>Cc1ccc2c(c1)c1c(n2CC(C)c2ccc(C)nc2)CCN(C)C1,,CN1CCCC1=O,,[K+].[OH-],,test
US06159967,CC(C)(C)[Si](C)(C)OCC[C@@H]1CN(c2ccc(Cl)c(Cl)c2)C(=O)CO1>>OCC[C@@H]1CN(c2ccc(Cl)c(Cl)c2)CCO1,,C1CCOC1,,,,test
US20100173793A1,N[C@@H](CCC(=O)N[C@@H](CSSC[C@@H](C(=O)NCC(=O)O)N(C(=O)CC[C@H](N)C(=O)O)c1ccccn1)C(=O)NCC(=O)O)C(=O)O>>N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(=O)O)C(=O)NCC(=O)O)C(=O)NCC(=O)O)C(=O)O,,CO,ClCCl,CC(=O)O,,test
US05506256,C1COCCO1.COc1ccc(OCC(O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)OC(C)(C)C)cc1>>COc1ccc(OCC(O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)COc2ccccc2)cc1,,C1COCCO1,Cl,,,test
US20100256357A1,CC(=O)OCC#N.CCO.Cl>>CCOC(=N)COC(C)=O.Cl,,CCOCC,,,,test
US05646184,CCCCC(CC)COc1ccc(C(=O)OC)c(O)c1>>CCCCC(CC)COc1ccc(C(=O)O)c(O)c1,,CO,,[K+].[OH-],,test
US20140323468A1,CC(C)(C)OC(=O)N1CCC(=O)c2cc(Br)cnc21.O=C=NC(=O)c1ccccc1>>O=C(NC(=O)N1CCC(=O)c2cc(Br)cnc21)c1ccccc1,,ClCCl,,,,test
US20050038041A1,CSc1nc(-c2nn[nH]n2)c(I)c(C(F)(F)F)n1.C[Si](C)(C)C=[N+]=[N-]>>CSc1nc(-c2nnn(C)n2)c(I)c(C(F)(F)F)n1,,CO,,c1ccccc1,,test
US20130231325A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.O=c1c(-c2ccc([N+](=O)[O-])cc2)coc2cc(O)ccc12>>O=c1c(-c2ccc([N+](=O)[O-])cc2)coc2cc(OS(=O)(=O)C(F)(F)F)ccc12,,ClCCl,,c1ccncc1,,test
US20070265262A1,NC1CC1.O=C(O)Cc1cccc(Br)c1>>O=C(Cc1cccc(Br)c1)NC1CC1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20140315888A1,Cc1c(Br)cnc2nc(N3CC(N(C)C(=O)OC(C)(C)C)C3)c(Cl)nc12.NN>>Cc1c(Br)cnc2nc(N3CC(N(C)C(=O)OC(C)(C)C)C3)c(NN)nc12,,CCO,,O,,test
US04957928,CCOC(=O)CCCN(CCBr)CCC1COc2ccccc2C1>>CCOC(=O)C1CCN(CCC2COc3ccccc3C2)CC1,,CN(C)C=O,,C,C[O-].[Na+],test
US20150175621A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1ncc(Sc2ccccc2)cn1>>CC(C)(C)OC(=O)NCc1ncc(Sc2ccccc2)cn1,,ClCCl,O,CCN(CC)CC,,test
US20120157430A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.COc1c(C(C)Nc2ncnc3c2ncn3C2CCCCO2)cc(Cl)c(F)c1Br>>COc1c(C(C)Nc2ncnc3[nH]cnc23)cc(Cl)c(F)c1C1=CCN(C(=O)OC(C)(C)C)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20020107251A1,Nc1ccccn1.O=C(O)c1cccc(-n2c(=O)c(Cc3ccccc3)nc3cccnc32)c1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>O=C(Nc1cccc(-n2c(=O)c(Cc3ccccc3)nc3cccnc32)c1)Nc1ccccn1,,CCOC(C)=O,O,CCN(CC)CC,Cc1ccccc1,test
US20120225863A1,COC(=O)c1ccc2nc(-c3ccc(F)cc3)c(Cl)nc2c1.FC(F)(F)[C@H]1CCCN1>>COC(=O)c1ccc2nc(-c3ccc(F)cc3)c(N3CCC[C@@H]3C(F)(F)F)nc2c1,,CS(C)=O,,,,test
US20120010191A1,O=[N+]([O-])c1ccn(C2CC2)n1>>Nc1ccn(C2CC2)n1,,CCO,,,,test
US05086070,CC(C)(C)N.O=C(c1ccc(OCCCCl)cc1)c1cccc2[nH]ccc12>>CC(C)(C)NCCCOc1ccc(C(=O)c2cccc3[nH]ccc23)cc1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20060058554A1,COc1cc(/C=C/C=C/C(=O)O)ccc1O.NCc1ccccc1>>COc1cc(/C=C/C=C/C(=O)NCc2ccccc2)ccc1O,,CN(C)C=O,ClCCl,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20160194304A1,C[C@@H]1Cc2ccccc2CN1C(=O)c1cc2c(cc1-c1cc(C(=O)N(C)c3ccc(OCc4ccccc4)cc3)c3n1CCCC3)CCN(C(=O)Cc1cccc(N3CCN(C)CC3)c1)C2>>C[C@@H]1Cc2ccccc2CN1C(=O)c1cc2c(cc1-c1cc(C(=O)N(C)c3ccc(O)cc3)c3n1CCCC3)CCN(C(=O)Cc1cccc(N3CCN(C)CC3)c1)C2,[Pd],CCO,,,,test
US20020147160A1,CO[C@]1(C)[C@H](OCc2ccc(Cl)cc2Cl)[C@@H](COCc2ccc(Cl)cc2Cl)O[C@H]1n1cc(C)c2c(=O)[nH]c(N)nc21>>CO[C@]1(C)[C@H](O)[C@@H](COCc2ccccc2)O[C@H]1n1cc(C)c2c(=O)[nH]c(N)nc21,[Pd],CCN(CC)CC,CO,,,test
US20150126490A1,Cc1cccc(/C=N/O)n1>>Cc1cccc(CN)n1,[Zn],CCO,,CC(=O)O,,test
US20130023526A1,COC(=O)c1cc(CO[Si](C)(C)C(C)(C)C)nc(C)n1.COc1cc(CN)ccc1F>>COc1cc(CNC(=O)c2cc(CO[Si](C)(C)C(C)(C)C)nc(C)n2)ccc1F,,CO,,CCN(C(C)C)C(C)C,,test
US20060235033A1,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.C[C@H](N)c1nccs1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)N[C@@H](C)c4nccs4)cc3)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20100093811A1,CC(C)CCN([C@@H](CCCCOCc1ccccc1)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)S(=O)(=O)c1ccc(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1>>CC(C)CCN([C@@H](CCCCO)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)S(=O)(=O)c1ccc(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1,,CCO,,,,test
US05646173,CC=CCC1Cc2cc(Cl)c(Cl)cc2C1=O.O=[O+][O-]>>O=CCC1Cc2cc(Cl)c(Cl)cc2C1=O,,CO,ClCCl,,,test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4c([N+](=O)[O-])cc(C(F)(F)F)cc4nn23)CC1.Cl>>Cl.O=c1cc(C2CCNCC2)n2nc3cc(C(F)(F)F)cc([N+](=O)[O-])c3c2[nH]1,,C1COCCO1,CO,,,test
US20080234262A1,Clc1nc(N2CCOCC2)c2cnn(C3CCNCC3)c2n1.O=S(=O)(CC(F)(F)F)OC(Cl)(Cl)Cl>>FC(F)(F)CN1CCC(n2ncc3c(N4CCOCC4)nc(Cl)nc32)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04663341,Clc1ccc(C2=NNCC2c2ccccc2)cc1.O=C=Nc1ccc(Cl)cc1>>O=C(Nc1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1,,CCOCC,,,,test
US05728370,CC1(C)Oc2cc3c(c(C(=O)O)c2O1)OC(C)(C)O3.CI>>COC(=O)c1c2c(cc3c1OC(C)(C)O3)OC(C)(C)O2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04992090,CC1(C)Cc2sccc2C1=O.N>>CC1(C)Cc2sccc2C1N,[Pt],C1CCOC1,,[H][H],,test
US05100457,COC(=O)Oc1cc(N2C(=O)OC(C(C)C)C2=O)c(F)cc1Cl>>CC(C)C1OC(=O)N(c2cc(O)c(Cl)cc2F)C1=O,,CO,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20130171459A1,O=C1C=CC(=O)N1c1ccc(Cc2ccc(N3C(=O)C=CC3=O)cc2)cc1.O=C1CC(=O)NC(=O)N1>>O=C1C=CC(=O)N1c1ccc(Cc2ccc(N3C(=O)C=CC3=O)cc2)cc1.O=C1CC(=O)NC(=O)N1,,CN1CCCC1=O,,,,test
US20160257951A1,C#CCCCCCCCCO.CCC#CCC#CCBr>>CCC#CCC#CCC#CCCCCCCCCO,[Cu]I,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20030162780A1,CCN(CC1CCN(C(=O)OC(C)(C)C)CC1)C1CCc2ccc(NC(=O)C(F)(F)F)cc2C1>>CCN(CC1CCNCC1)C1CCc2ccc(NC(=O)C(F)(F)F)cc2C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120283242A1,CN(C)C=O.Fc1ccc(OCCc2ccc(Br)cc2)cc1>>O=Cc1ccc(CCOc2ccc(F)cc2)cc1,,CCCCCC,,C1CCOC1,[Li]CCCC,test
US20090099175A1,CCc1cc(C(C)=O)c(NC(C)=O)cc1OC>>CCc1cc(C(C)=O)c(N)cc1OC,,C1COCCO1,,Cl,,test
US20090203750A1,CC(C)(C)OC(=O)NC[C@@H]1C[C@H]1c1cccc(Br)c1.OB(O)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)NC[C@@H]1C[C@H]1c1cccc(-c2ccc(Cl)cc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20140004243A1,COc1cccc(OC)c1/C=N/NC(=S)N[C@H](C)c1ccccc1>>COc1cccc(OC)c1CNNC(=S)N[C@H](C)c1ccccc1,,CO,,Cl,[BH4-].[Na+],test
US20100216836A1,OCCCl.Oc1cccc([C@H]2CCCN(C[C@H]3COc4ccccc4O3)C2)c1>>OCCOc1cccc([C@H]2CCCN(C[C@H]3COc4ccccc4O3)C2)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05276120,CCN(CC)S(F)(F)F.CCOC(OCC)C(O)CN=[N+]=[N-]>>CCOC(OCC)C(F)CN=[N+]=[N-],,c1ccccc1,,,,test
US05382688,C1CCOC1.O=C1CCC(c2ccccc2)(c2ccccc2)CC1>>CCCCC1=CCC(c2ccccc2)(c2ccccc2)CC1,,C1CCOC1,,,,test
US20140086837A1,O=C(CNC(=O)c1ccc(F)c([N+](=O)[O-])c1)OCc1ccccc1>>Nc1cc(C(=O)NCC(=O)O)ccc1F,[Pd],CCOC(C)=O,,,,test
US20070015758A1,CCI.CCOC(=O)c1[nH]c2ccccc2c1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1>>CCOC(=O)c1c(CN(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(C)n2)c2ccccc2n1CC,,CN(C)C=O,,[H-].[Na+],,test
US20140288040A1,CC(C)(C)[S@@](=O)/N=C/c1ccc(Cl)c(O[Si](C)(C)C(C)(C)C)c1F.CC[Mg]Br>>CC[C@@H](N[S@](=O)C(C)(C)C)c1ccc(Cl)c(O[Si](C)(C)C(C)(C)C)c1F,,C1CCOC1,,,,test
US20050148604A1,COc1ccccc1C(=O)Nc1c(C)nn(C2CCCCC2)c1C(N)=O>>COc1ccccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1,,O,,CCO,[Na+].[OH-],test
US20070259881A1,CC(C)(O)CNc1c(N)cnc2ccccc12.O=C(Cl)CCl>>CC(C)(O)Cn1c(CCl)nc2cnc3ccccc3c21,,ClCCl,,CCN(CC)CC,,test
US20150376136A1,CC1(C2CCCCC2)NC(=O)NC1=O.CON(C)C(=O)CCl>>CON(C)C(=O)CN1C(=O)NC(C)(C2CCCCC2)C1=O,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20030134748A1,CNN.CSC(=NC(=O)c1cscc1C)c1c(F)cccc1Cl>>Cc1cscc1-c1nc(-c2c(F)cccc2Cl)nn1C,,Cc1ccccc1,,,,test
US20080194812A1,CC(=O)OC(C)=O.C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)C[C@H](O)[C@@H]12>>CC(=O)O[C@H]1CC[C@@]2(C)CC[C@H]3[C@@H](C(=O)CC4=CC(=O)CC[C@@]43C)[C@H]12,CN(C)c1ccncc1,C1CCOC1,,O,,test
US20140171446A1,CCC(=O)c1ccc(N)nc1.Cc1c(F)cncc1C(=O)O>>CCC(=O)c1ccc(NC(=O)c2cncc(F)c2C)nc1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20140357661A1,COC(=O)/C=C/c1cc(F)c(C=O)c(F)c1.C[C@H](Cc1c[nH]c2ccccc12)NCC(C)(F)CO>>COC(=O)/C=C/c1cc(F)c([C@@H]2c3[nH]c4ccccc4c3C[C@@H](C)N2CC(C)(F)CO)c(F)c1,,Cc1ccccc1,,CC(=O)O,,test
US04576749,Nc1ccccc1.O=C(CBr)OCc1ccccc1>>O=C(CNc1ccccc1)OCc1ccccc1,,CN(C)C=O,,CC(=O)[O-].[Na+],,test
US04609641,COC(=O)[C@H](CC(C)C)NCC[C@H](O)[C@H](CC(C)C)NC(=O)OC(C)(C)C>>CC(C)C[C@H](NCC[C@H](O)[C@H](CC(C)C)NC(=O)OC(C)(C)C)C(=O)O,,C1COCCO1,O,[Na+].[OH-],,test
US20070155767A1,NCC1(O)CC1.O=[N+]([O-])c1cnc2ccccc2c1Cl>>O=[N+]([O-])c1cnc2ccccc2c1NCC1(O)CC1,,ClCCl,,CCN(CC)CC,,test
US05037825,Cc1ccc(S(=O)(=O)OC(OS(=O)(=O)c2ccc(C)cc2)C(C)(C)C)cc1.Sc1ccccc1S>>CC1(C)CSc2ccccc2SC1,,CS(C)=O,,[H-].[Na+],,test
US20030171303A1,CC(C)C1SCCCS1.CCCC=O>>CCCC(O)C1(C(C)C)SCCCS1,,C1CCOC1,,[Li]CCCC,,test
US20090143402A1,CCOC(=O)c1c(C)n(-c2ccccc2)c(=O)c2ccccc12>>Cc1c(C(=O)O)c2ccccc2c(=O)n1-c1ccccc1,,CO,O,[Na+].[OH-],,test
US04503051,O=CNCCCOc1cccc(CN2CCCCC2)n1>>NCCCOc1cccc(CN2CCCCC2)n1,,CO,,[K+].[OH-],,test
US20150038438A1,COc1ccc(CN)c(OC)c1.O=C1CCCN(C(=O)OCc2ccccc2)c2cc(Cl)ccc21>>COc1ccc(CN=C2CCCN(C(=O)OCc3ccccc3)c3cc(Cl)ccc32)c(OC)c1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,CCN(CC)CC,,test
US04678500,COC(=O)c1cccc([N+](=O)[O-])c1CBr.NC(N)=S>>Br.COC(=O)c1cccc([N+](=O)[O-])c1CSC(=N)N,,CO,,,,test
US20030153580A1,C1CNCCN1.COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2)c(OC2CCCC2)c1.O=C(Cl)Cl>>COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2C(=O)N2CCNCC2)c(OC2CCCC2)c1,,C1CCOC1,ClCCl,CCN(CC)CC,O=C([O-])O.[Na+],test
US20150038437A1,CCCC(=NC(C)(C)C)c1ccc2c(c1)CCCN2C.COC(=O)C(C(=O)OC)C(=O)OC>>CCc1c(-c2ccc3c(c2)CCCN3C)[nH]c(=O)c(C(=O)OC)c1O,,COCCOCCOC,,,,test
US20050203160A1,CC(C)(C)OC(=O)Cn1ccc2ccc(OCc3cc(-c4ccc(C(F)(F)F)cc4)[nH]n3)cc21>>O=C(O)Cn1ccc2ccc(OCc3cc(-c4ccc(C(F)(F)F)cc4)[nH]n3)cc21,,C1CCOC1,CO,[Li+].[OH-],,test
US20080090802A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)NC(=O)CNC(=O)c1cc(N2CCCNC(C)C2)ccc1[N+](=O)[O-]>>CC(C)NC(=O)CNC(=O)c1cc(N2CCCN(C(=O)OC(C)(C)C)C(C)C2)ccc1[N+](=O)[O-],,ClCCl,,,,test
US20030069257A1,CCn1c(Cc2ccnn2-c2cccc(F)c2)nc2cc(C(C)=O)ccc21.CON>>CCn1c(Cc2ccnn2-c2cccc(F)c2)nc2cc(C(C)=NOC)ccc21,,CO,,Cl,CC(=O)[O-].[Na+],test
US06509341B1,CCCNCCO.O=S(=O)(Cl)c1ccccc1>>CCCN(CCO)S(=O)(=O)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20140213586A1,CNC.COc1cc([N+](=O)[O-])cnc1Cl>>COc1cc(N)cnc1N(C)C,[Pd],,,C1CCOC1,,test
US20140121198A1,C[C@@H](O)c1nc2cnc3ccsc3c2n1[C@H]1CC[C@H](CC#N)OC1>>CC(=O)c1nc2cnc3ccsc3c2n1[C@H]1CC[C@H](CC#N)OC1,,ClCCl,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US20110230463A1,CCOC(=O)c1cn[nH]c1.Fc1cc(OCc2ccc(C(F)(F)F)cc2C(F)(F)F)cc2c1C=C(CBr)CO2>>CCOC(=O)c1cnn(CC2=Cc3c(F)cc(OCc4ccc(C(F)(F)F)cc4C(F)(F)F)cc3OC2)c1,,CN(C)C=O,,[H-].[Na+],,test
US20120202834A1,CCOC(=O)CCNC(=O)c1ccc(C(=O)C2CC(C)(C)C2)cc1>>CCOC(=O)CCNC(=O)c1ccc(C(O)C2CC(C)(C)C2)cc1,,CO,,[BH4-].[Na+],,test
US04804661,COc1cccc(C(=O)Cl)c1.c1ccc(CN2CCNCC2)cc1>>COc1cccc(C(=O)N2CCNCC2)c1,,ClCCl,,CCN(CC)CC,,test
US20070003539A1,CC(C)S(=O)(=O)c1ccccc1C#N.Cl>>CC(C)S(=O)(=O)c1ccccc1CN.Cl,[Pd],CO,,,,test
US20070208062A1,CC(C)(C)OC(=O)COC[C@@H]1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1>>O=C(O)COC[C@@H]1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1,,CCOCC,,O=C(O)C(F)(F)F,,test
US20100041905A1,C=C(C)COc1cc(OC(C)=O)ccc1NC(C)=O>>C=C(C)COc1cc(O)ccc1NC(C)=O,,CO,,N,,test
US20080293775A1,COc1cc(Cl)ccc1CCC#N>>N#CCCc1ccc(Cl)cc1O,,ClCCl,,BrB(Br)Br,,test
US20070043048A1,CC1(C)CC(N(c2ccc(Br)cc2)c2ncccn2)CC(C)(C)N1.CCCC[Sn](CCCC)(CCCC)c1ccncc1>>CC1(C)CC(Nc2nccc(-c3ccc(-c4ccncc4)cc3)n2)CC(C)(C)N1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,Cc1ccccc1C,,test
US20130072467A1,COC(=O)C1CN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)C1>>OCC1CN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)C1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050245554A1,CSc1ncc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1.OCc1cccc(F)c1>>Fc1cccc(COc2ncc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)n2)c1,,CCCCCC,CCOC(C)=O,,,test
US20040063720A1,CN(C)C=O.Nc1cc(CO)ncn1.O=P(Cl)(Cl)Cl>>CN(C)C=Nc1cc(CCl)ncn1,,ClCCl,,CCN(CC)CC,,test
US20150291563A1,CC(C)(C)OC(=O)N1CCN(c2cc(C3CC(C(F)(F)C(F)(F)F)=NN3c3ccc(F)cc3F)ccn2)CC1.Cl>>Cl.Fc1ccc(N2N=C(C(F)(F)C(F)(F)F)CC2c2ccnc(N3CCNCC3)c2)c(F)c1,,CCOC(C)=O,,,,test
US05478838,Nc1cc(N)ncn1.O=C(Cl)OCc1ccccc1>>NC1=CC(N)=NCN1C(=O)OCc1ccccc1,,CCO,O,Cl,[Na+].[OH-],test
US20110306607A1,CC(=O)OCc1ccc2c(c1)OC1(CCN(C(=O)c3ccc(S(=O)(=O)C(C)C)cc3)CC1)c1ccc(C#N)n1-2>>CC(C)S(=O)(=O)c1ccc(C(=O)N2CCC3(CC2)Oc2cc(CO)ccc2-n2c(C#N)ccc23)cc1,,CO,,C1CCOC1,[Li+].[OH-],test
US20160200704A1,CC(C)(C)OC(=O)NCc1cc2cc[nH]c2cc1F.O=C1CCC(=O)N1Cl>>CC(C)(C)OC(=O)NCc1cc2c(Cl)c[nH]c2cc1F,,ClCCl,,,,test
US20070032532A1,CI.COCOc1cc(CCO)c(-c2ccccc2)c(OCOC)c1>>COCCc1cc(OCOC)cc(OCOC)c1-c1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US20080076924A1,CC(C)(C)OC(=O)OC(C)(C)C.Nc1cccc2ncccc12>>CC(C)(C)OC(=O)Nc1cccc2ncccc12,,C1CCOC1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US20090270402A1,Clc1cnc(Cl)cn1.NN>>NNc1cnc(Cl)cn1,,O,,[NH4+].[OH-],,test
US20020045613A1,N#Cc1cccc(C2CCNCC2)c1.O=C(O)c1cncc(C#Cc2ccccc2)c1>>N#Cc1cccc(C2CCN(C(=O)c3cncc(C#Cc4ccccc4)c3)CC2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110190334A1,C=CCC1(S(=O)(=O)Cl)CC1.Cc1c(Nc2ccc(I)cc2F)c(N)c2n(c1=O)CCS2>>C=CCC1(S(=O)(=O)Nc2c(Nc3ccc(I)cc3F)c(C)c(=O)n3c2SCC3)CC1,,c1ccncc1,,,,test
US04060619,CC(=O)C1COc2ccccc2C1=O.CCOC(=O)C(=O)OCC>>CCOC(=O)C(=O)CC(=O)C1COc2ccccc2C1=O,,C1CCOC1,,CC(=O)O,[H-].[Na+],test
US20050256103A1,C=CCc1ccc(CO)cc1O.O=[N+]([O-])O>>C=CCc1cc([N+](=O)[O-])c(CO)cc1O,,CC(=O)O,,[Na+].[OH-],,test
US20080039517A1,CCNC[C@H](CC(=O)OC(C)(C)C)Nc1ccc(C#N)c(Cl)c1>>CCN1C[C@@H](Nc2ccc(C#N)c(Cl)c2)CC1=O,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080085890A1,CCCC[Sn](CCCC)(CCCC)c1ccco1.N#Cc1ccc(I)c(O)c1>>N#Cc1ccc(-c2ccco2)c(O)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,,,test
US20110269780A1,CCOC(=O)C[C@H](c1ccccc1)n1c(=O)n(Cc2cn(C)c3cccc(C)c23)c2cnc(C3CC3)nc21>>Cc1cccc2c1c(Cn1c(=O)n([C@H](CC(=O)O)c3ccccc3)c3nc(C4CC4)ncc31)cn2C,,C1CCOC1,O,Cl,[Li+].[OH-],test
US09278910B2,COc1ccc(CC(=O)Nc2ccc(C(=O)N(CC(=O)OC(C)(C)C)Cc3ccc(C(=O)O)cc3)cc2)c(C(F)(F)F)c1.Cc1ccc(-c2ccc(C(N)=NN)cc2)cc1>>COc1ccc(CC(=O)Nc2ccc(C(=O)N(Cc3ccc(-c4n[nH]c(-c5ccc(-c6ccc(C)cc6)cc5)n4)cc3)C(C(=O)O)C(C)(C)C)cc2)c(C(F)(F)F)c1,,C1COCCO1,CN(C)C=O,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20090156603A1,CC(C)(C)OC(=O)N1CCN(CC(O)CCl)C(=O)C1>>CC(C)(C)OC(=O)N1CCN(CC(=O)CCl)C(=O)C1,,CC#N,CCOC(C)=O,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04507498,BrCCCCCBr.CCCc1c(OCC(=O)OCC)ccc(C(C)=O)c1O>>CCCc1c(OCC(=O)OCC)ccc(C(C)=O)c1OCCCCCBr,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090054405A1,CC(=O)Nc1nc2ccc(C3OC(C)(C)C(C)(C)O3)cc2s1.Nc1cccc(Br)n1>>CC(=O)Nc1nc2ccc(-c3cccc(N)n3)cc2s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20020160996A1,Br.COc1cc2c(cc1OC)CN(c1c(C)c(C)c3c(c1C)C(c1ccc(C)cc1)C(C)(C)O3)C2>>Br.COc1cc2c(cc1OC)CN(c1c(C)c(C)c3c(c1C)C(c1ccc(C)cc1)C(C)(C)O3)C2,,CC(=O)O,,,,test
US20040132727A1,CC(O)c1cccc(N(C)C)c1.COc1cc2nccc(Oc3cc(C)c(N)cc3C)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3cc(C)c(NC(=O)OC(C)c4cccc(N(C)C)c4)cc3C)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20120302567A1,CCOC(=O)c1cn(Cc2ccccc2)c2c(=O)[nH]cnc12>>O=C(O)c1cn(Cc2ccccc2)c2c(=O)[nH]cnc12,,C1CCOC1,O,[Li+].[OH-],,test
US20160039804A1,CCN(c1ncc(C(F)(F)F)cc1CN1C(=O)O[C@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H]1C)C1CCN(CC(=O)OC)CC1>>CCN(c1ncc(C(F)(F)F)cc1CN1C(=O)O[C@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H]1C)C1CCN(CC(=O)O)CC1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20120196853A1,C1COCCN1.C=O.Oc1cccc2cccnc12>>Cc1ccc2ccc(N3CCOCC3)c(O)c2n1,,CCO,,,,test
US20160237090A1,CI.C[C@H]1Cn2ncc(N3CC(S)CC3=O)c2CN1C(=O)OC(C)(C)C>>CSC1CC(=O)N(c2cnn3c2CN(C(=O)OC(C)(C)C)[C@@H](C)C3)C1,,CN(C)C=O,,[H-].[Na+],,test
US20150284363A1,Cl.O=C(Nc1cnccc1OC1CNC1)c1ccc(F)c(-c2c(F)cccc2F)n1>>NCC(CCl)Oc1ccncc1NC(=O)c1ccc(F)c(-c2c(F)cccc2F)n1,,CO,,,,test
US20070142434A1,Cc1ccc(S(=O)(=O)OC[C@H]2CCCN2C(=O)OC(C)(C)C)cc1.O=C1c2ccccc2C(=O)N1c1ccc(O)cc1>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc(N2C(=O)c3ccccc3C2=O)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20060089344A1,N.O=C1COC(=O)N1CCC1CCN(c2ccc3cc(Cl)ccc3n2)CC1>>NC(=O)COC(=O)NCCC1CCN(c2ccc3cc(Cl)ccc3n2)CC1,,CO,,,,test
US06140351,CC(C)(O)CN.CCN=C=O>>CCNC(=O)NCC(C)(C)O,,ClCCl,,,,test
US20150266867A1,CC(C)(C)OC(=O)Nc1nc(/C(=N/OC(C)(C)C(=O)OC(C)(C)C)C(=O)N[C@@H]2C(=O)N[C@@H]2CNCCN)cs1.O=C(n1ccnc1)n1ccnc1>>CC(C)(C)OC(=O)Nc1nc(/C(=N/OC(C)(C)C(=O)OC(C)(C)C)C(=O)N[C@@H]2C(=O)N[C@@H]2CN2CCNC2=O)cs1,,CCOC(C)=O,ClC(Cl)Cl,,,test
US20100216746A1,CCC(=O)NC(C#N)COCc1ccccc1.ClC(Cl)(Cl)Cl>>CCc1nc(Cl)c(COCc2ccccc2)[nH]1,,CC#N,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140371220A1,Clc1ccc(Cl)nn1.Fc1ccc2c(c1)N(C1CCNCC1)CC2>>Fc1ccc2c(c1)N(C1CCN(c3ccc(Cl)nn3)CC1)CC2,,CS(C)=O,O,CCN(CC)CC,Cl,test
US20050215570A1,COc1cnc(OC)n2nc(N)nc12.CSC.O=C1CCC(=O)N1Cl>>COc1cnc(OC)n2nc(N=S(C)C)nc12.Cl,,CC#N,ClCCl,,,test
US20050261350A1,CC(C)Br.O=Cc1cc(F)c(O)c(F)c1>>CC(C)Oc1c(F)cc(C=O)cc1F,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20050020684A1,BrC(Br)(Br)Br.OCCCOc1ccc(-c2ccccc2)cc1>>BrCCCOc1ccc(-c2ccccc2)cc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150038528A1,COC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O.NC(CC(=O)O)c1cccc(Cl)c1>>N#Cc1nc(C(=O)NC(CC(=O)O)c2cccc(Cl)c2)c(O)c2ccc(Oc3ccccc3)cc12,,CC(=O)N(C)C,O,Cl,C[O-].[Na+],test
US20060264415A1,O=C(COCc1ccc(F)cc1)NCCC1CCNCC1.O=C(n1ccnc1)n1ccnc1.OCCc1c[nH]c2ccccc12>>O=C(COCc1ccc(F)cc1)NCCC1CCN(C(=O)OCCc2c[nH]c3ccccc23)CC1,,ClCCl,,Cl,,test
US20130225619A1,BrCC1CCCCC1.O=C(O)c1ccc(Cl)s1>>O=C(OCC1CCCCC1)c1ccc(Cl)s1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20040133008A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(NCCn2cccn2)cc1>>CC(C)(C)OC(=O)N(CCn1cccn1)c1ccc([N+](=O)[O-])cc1,CN(C)c1ccncc1,C1CCOC1,,,,test
US04083979,CC(=O)NS(=O)(=O)c1cc(C(=O)CBr)ccc1Cl.CNC(=S)NC>>Br.CN=C1SCC(O)(c2ccc(Cl)c(S(=O)(=O)NC(C)=O)c2)N1C,,CC(C)=O,CCO,,,test
US20070167476A1,CC(C)(C)OC(=O)NCCCn1c(CCl)nc2cnc3cc(OCc4ccccc4)ccc3c21>>CC(C)(C)OC(=O)N1CCCn2c(nc3cnc4cc(OCc5ccccc5)ccc4c32)C1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20100240702A1,CC(C)(C)OC(=O)n1ccc2c(CO)cc(Cl)cc21.COC(=O)CCn1c(=O)[nH]c2ccccc21>>COC(=O)CCn1c(=O)n(Cc2cc(Cl)cc3c2ccn3C(=O)OC(C)(C)C)c2ccccc21,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060293311A1,CCN(CC)CC.CO.N#CCOc1ccc([N+](=O)[O-])cc1.NO>>Cc1nc(COc2ccc([N+](=O)[O-])cc2)no1,,CO,,Cl,,test
US20130281490A1,CC(C)[C@H](O)[C@@H](N)C(=O)O.O=C([O-])n1cccc(CCCCCc2ccccc2)c1=O>>CC(C)[C@H](O)[C@@H](NC(=O)OCCCCCc1ccccc1)C(=O)O,,C1CCOC1,O,O=C([O-])O.[Na+],,test
US05650428,CCC[C@H](NS(=O)(=O)c1ccc(Cl)cc1)C(O)=S.CCOC(=O)c1cccc(N)c1>>CCC[C@H](NS(=O)(=O)c1ccc(Cl)cc1)C(=S)Nc1cccc(C(=O)OCC)c1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20080194572A1,COC(=O)[C@H](C)N(Cc1ncc(C)c(OC)c1C)c1nc(Cl)ncc1[N+](=O)[O-].N>>COC(=O)[C@H](C)N(Cc1ncc(C)c(OC)c1C)c1nc(N)ncc1[N+](=O)[O-],,C1CCOC1,,,,test
US03993704,BrBr.O=[N+]([O-])c1ccc(C(Br)Br)cc1>>O=[N+]([O-])c1ccc(C(Br)(Br)Br)cc1,,O,,Cc1ccccc1,[Na+].[OH-],test
US20160009662A1,COC(=O)C[C@H](c1cccc(OCc2cnc(-c3cc(OC)ncc3F)c(CC(C)C)n2)c1)C1CC1>>COc1cc(-c2ncc(COc3cccc([C@@H](CC(=O)O)C4CC4)c3)nc2CC(C)C)c(F)cn1,,C1CCOC1,O,[Li]O,,test
US04228103,O=CNc1ccccc1.O=[N+]([O-])c1ccc(Cl)cc1>>O=[N+]([O-])c1ccc(Nc2ccccc2)cc1,,Cc1ccccc1C,O,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US04797129,CNc1cc(Cl)cc(NC)c1[N+](=O)[O-].O=[N+]([O-])c1c(Cl)cc(Cl)cc1Cl>>CNc1cc(Cl)cc(Cl)c1[N+](=O)[O-],,CCO,,CN,,test
US20060211682A1,CC(=O)C(=O)O.CCN(CC)CC.ClCCCl.On1nnc2ccccc21>>CC(=O)C(=O)N1CCC[C@@H]1CC#N,,ClCCl,O=C(O)C(F)(F)F,,,test
US06218397B1,CN=C=O.CSc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(C)nc(N(CCCO)Cc3ccccc3)c12>>CNC(=O)OCCCN(Cc1ccccc1)c1nc(C)nc2c1c(SC)nn2-c1c(Cl)cc(Cl)cc1Cl,,C1CCOC1,,[H-].[Na+],,test
US20080255083A1,C1CCNC1.O=c1cc(OCc2ccccc2F)ccn1CCc1ccc(CBr)cc1>>O=c1cc(OCc2ccccc2F)ccn1CCc1ccc(CN2CCCC2)cc1,,CN(C)C=O,,,,test
US06689806B1,O=C1Cc2c(CCO)cccc2N1.O=Cc1ccc(Br)cc1>>O=C1Nc2cccc(CCO)c2C1=Cc1ccc(Br)cc1,,CCO,,C1CCNCC1,,test
US05338742,Cc1ccccn1.Clc1ccc(Oc2ccc(CCBr)cc2)cc1>>Clc1ccc(Oc2ccc(CCCc3ccncc3)cc2)cc1,,C1CCOC1,,O,CC(C)[N-]C(C)C.[Li+],test
US20080221180A1,CC(=O)Nc1nc(C)c(-c2cc(S(=O)(=O)Cl)sc2Br)s1.CC(C)(C)OC(=O)N1CCNCC1>>CC(=O)Nc1nc(C)c(-c2cc(S(=O)(=O)N3CCN(C(=O)OC(C)(C)C)CC3)sc2Br)s1,,ClCCl,,CCN(CC)CC,,test
US04910318,CC(C)(C)OC(=O)ON=C(C#N)c1ccccc1.CNCC1CCSc2c1n(C)c1ccccc21>>CN(CC1CCSc2c1n(C)c1ccccc21)C(=O)OC(C)(C)C,,C1CCOC1,,CCN(CC)CC,,test
US20050124622A1,CC(C)(C)OC(=O)NN.COC(=O)c1ccc(C(C)=O)cc1>>COC(=O)c1ccc(C(C)NNC(=O)OC(C)(C)C)cc1,Cl,C1CCOC1,,,,test
US20050240017A1,O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(Cc2ccccc2O)sc2cc(O)ccc12>>Oc1ccc2c3c(sc2c1)Cc1ccccc1OC3c1ccc(OCCN2CCCCC2)cc1,,C1CCOC1,,CC(C)C[AlH]CC(C)C,,test
US20090221586A1,CCOc1ccccc1C(=O)NCc1coc(-c2ccc(OC)c(O)c2)n1.FC(F)(F)CI>>CCOc1ccccc1C(=O)NCc1coc(-c2ccc(OC)c(OCC(F)(F)F)c2)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070054942A1,ON=C(c1ccncc1)c1cc(F)c(Br)cc1F>>Fc1cc2c(-c3ccncc3)noc2cc1Br,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20050267188A1,Nc1ccc(Cl)cc1.O=Cc1ncc[nH]1>>Clc1ccc(NCc2ncc[nH]2)cc1,,CO,,O,[BH4-].[Na+],test
US05446150,CN(C)c1ccc(C(=CC2=CC(=O)C(=O)c3ccccc32)c2ccc(N(C)C)cc2)cc1.NO>>CN(C)c1ccc(C(=Cc2cc(O)c(N=O)c3ccccc23)c2ccc(N(C)C)cc2)cc1,,CCO,,Cl,,test
US20010009293A1,Nc1ccc(I)c(I)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1ccc(I)c(I)c1)C(F)(F)F,,CC#N,,c1ccncc1,,test
US20130102586A1,COc1ccc(Cn2nc(C)c3cc(-c4cnn(C)c4)cnc32)cc1>>Cc1n[nH]c2ncc(-c3cnn(C)c3)cc12,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US05571810,CS(=O)(=O)c1ccc(-c2cc(C(=O)Cl)sc2-c2ccc(F)cc2)cc1>>CS(=O)(=O)c1ccc(-c2cc(CO)sc2-c2ccc(F)cc2)cc1,,C1COCCO1,CCOC(C)=O,[BH4-].[Na+],,test
US20140031364A1,O=C1CCC(=O)N1Cl.ON=Cc1ccc(OC(F)(F)F)cc1>>ON=C(Cl)c1ccc(OC(F)(F)F)cc1,,CN(C)C=O,,,,test
US04407814,COC(=O)C(C)(C)NC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1>>CC1(C)NC(=O)N(c2ccc(Cl)c(C(F)(F)F)c2)C1=O,,CC(C)=O,,Cl,,test
US20050182112A1,CCNC.CN(C)C=O.O=C1O[C@@H](Cn2cc(C=C(Br)Br)nn2)CN1c1ccc(C2=CCS(=O)(=O)CC2)c(F)c1>>CCN(C)C(=O)Cc1cn(C[C@H]2CN(c3ccc(C4=CCS(=O)(=O)CC4)c(F)c3)C(=O)O2)nn1,,CN(C)C=O,,O,,test
US20090036492A1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.O=Cc1c(F)cc(F)cc1F>>COc1cc(O)c2c(c1C(=O)NCc1c(F)cc(F)cc1F)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20150252036A1,COC(=O)C(C)OS(=O)(=O)c1ccc(C)cc1.COc1cc(O)ccc1Br>>COC(=O)C(C)Oc1ccc(Br)c(OC)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080280876A1,CC(C)Oc1ccc(-c2noc(-c3ccc(C=O)cc3)n2)cc1Br.CO.COC(OC)OC>>COC(OC)c1ccc(-c2nc(-c3ccc(OC(C)C)c(Br)c3)no2)cc1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20090162283A1,N#Cc1ccc(-c2cn3cc(I)ccc3n2)cc1.NO>>N=C(NO)c1ccc(-c2cn3cc(I)ccc3n2)cc1,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080085890A1,CC(C)(C)OC(=O)N1CCN(c2ccc(N)cc2)CC1.COC=C1C(=O)NC(=O)c2ccc(Br)cc21>>CC(C)(C)OC(=O)N1CCN(c2ccc(N/C=C3\C(=O)NC(=O)c4ccc(Br)cc43)cc2)CC1,,CN(C)C=O,,,,test
US20120245178A1,CC1(C)OB(c2cnn(C3CCCC3=O)c2)OC1(C)C>>CC1(C)OB(c2cnn(C3CCCC3O)c2)OC1(C)C,,CO,,[BH4-].[Na+],,test
US20090124596A1,C1CNCCOC1.CC(C)(C)OC(=O)N[C@H]1CC[C@@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccc(C=O)cc4)c3)c2=O)CC1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccc(CN5CCCOCC5)cc4)c3)c2=O)CC1,,ClCCCl,,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US06057369,BrCCCCc1ccccc1.COC(=O)CS(=O)(=O)c1ccc(OC)c(OC)c1>>COC(=O)C(CCCCc1ccccc1)S(=O)(=O)c1ccc(OC)c(OC)c1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20130216498A1,Cc1cnc(-c2cnc3ccc(F)cn23)nc1N[C@@H]1CCCN(C(=O)[C@H]2COC(C)(C)O2)C1>>Cc1cnc(-c2cnc3ccc(F)cn23)nc1N[C@@H]1CCCN(C(=O)[C@H](O)CO)C1,,O,,CC(=O)O,,test
US20050070574A1,CCOC(=O)C1CCCN(C2CCN(Cc3c(-c4ccccc4)nc4ccccc4c3C(=O)OC(C)(C)C)CC2)C1>>CCOC(=O)C1CCCN(C2CCN(Cc3c(-c4ccccc4)nc4ccccc4c3C(=O)O)CC2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100010038A1,CC#CC(=O)OCC.N#CCC1CCc2ccncc21.NOc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]>>CCOC(=O)c1c(C)nn2ccc3c(c12)C(CC#N)CC3,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20060135782A1,COc1cc2ncnc(Nc3nc4ccc(N)cc4s3)c2cc1OC.O=C=Nc1ccccc1>>COc1cc2ncnc(Nc3nc4ccc(NC(=O)Nc5ccccc5)cc4s3)c2cc1OC,,O,,,,test
US05120732,CC1(C)CN1.OCCS>>CC(C)(N)CSCCO,,COCCOC,,,,test
US20120046267A1,CC(C)(C)Sc1c(Br)cc([N+](=O)[O-])cc1C=NO>>O=[N+]([O-])c1cc(Br)c2sncc2c1,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05134138,CC(=O)Cl.CCOC(C)=O.COc1ccc(COc2ccc(C=O)cc2OCc2ccc(OC)cc2)cc1.ClCCl.c1ccncc1>>COc1ccc(COc2ccc(C(C)(O)OCc3ccccc3)cc2OCc2ccc(OC)cc2)cc1,,CCOC(C)=O,,,,test
US20040142172A1,O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21>>O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21,,O,,CS(C)=O,,test
US05380461,CCCc1ccc(I)cc1.[Li]CCCC>>[Li]c1ccccc1CCC,,CCCCCC,,,,test
US20080108608A1,CNc1cc(C(C)(C)C)on1.O=C(Nc1cccc(C#Cc2cnc(Cl)nc2)c1)Oc1ccccc1>>CN(C(=O)Nc1cccc(C#Cc2cnc(Cl)nc2)c1)c1cc(C(C)(C)C)on1,,C1CCOC1,CCN(CC)CC,,,test
US20080058384A1,CC1=C(C(=O)O)C(c2ccc3ccccc3c2)CC(=O)N1.Nc1ccc2[nH]ncc2c1>>CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc3ccccc3c2)CC(=O)N1,,CN(C)C=O,,,,test
US20100041728A1,C=CC1CC1(NC(=O)C1CC(OC(=O)c2ccc([N+](=O)[O-])cc2)CN1C(=O)OC(C)(C)C)C(=O)OCC>>C=CC1CC1(NC(=O)C1CC(OC(=O)c2ccc([N+](=O)[O-])cc2)CN1)C(=O)OCC,,ClCCl,O=C(O)C(F)(F)F,,,test
US04992433,CCOC(=O)c1ccc(OCCC2CCN(Cc3ccccc3)CC2)cc1.O=C(O)/C=C\C(=O)O>>CCOC(=O)c1ccc(OCCC2CCNCC2)cc1.O=C(O)CCC(=O)O,[Pd],CCO,,[H][H],,test
US20050026836A1,Nc1ncc(Cl)cc1CCl.Oc1ccccc1>>Nc1ncc(Cl)cc1COc1ccccc1,,C1CCOC1,,Cl,[H-].[Na+],test
US20110021769A1,CC(=O)O[C@@H]1[C@H](OC(C)=O)[C@@H](C)O[C@H]1n1cc(F)c(N)nc1=O.CCCCCOC(=O)Cl>>CCCCCOC(=O)Nc1nc(=O)n([C@@H]2O[C@H](C)[C@@H](O)[C@H]2O)cc1F,,O,,ClCCl,c1ccncc1,test
US20150105369A1,CC(C)(C)OC(=O)N1CC(C=O)C1.COc1nc2ccc(Br)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1>>COc1nc2ccc(C(O)C3CN(C(=O)OC(C)(C)C)C3)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1,,C1CCOC1,,[Li]CCCC,,test
US05595989,BrCCCOC1CCCCO1.O=c1c2ccccc2[nH]c2ccccc12>>O=c1c2ccccc2n(CCCOC2CCCCO2)c2ccccc12,,CN(C)C=O,,[H-].[Na+],,test
US20140148459A1,O=C(O)C(CCn1nnc2ccccc2c1=O)SCc1ccc(-c2ccc(Cl)cc2)cc1.O=S([O-])OO>>O=C(O)C(CCn1nnc2ccccc2c1=O)S(=O)(=O)Cc1ccc(-c2ccc(Cl)cc2)cc1,,CO,,O,,test
US20070219229A1,CC(C)(C)[Si](C)(C)n1ccc2c(Br)cnc(Cl)c21.O=C=O>>O=C(O)c1cnc(Cl)c2[nH]ccc12,,C1CCOC1,,[Li]C(C)(C)C,,test
US20110118246A1,CI.Nc1cc(Br)cc2[nH]ncc12>>Cn1ncc2c(N)cc(Br)cc21,,C1CCOC1,,[H-].[Na+],,test
US20150218096A1,CC(C)(C)OC(=O)Nc1cc2c(-c3ccc(C(=O)O)cc3F)cn(C(=O)c3c(Cl)cccc3C(F)(F)F)c2cn1>>Nc1cc2c(-c3ccc(C(=O)O)cc3F)cn(C(=O)c3c(Cl)cccc3C(F)(F)F)c2cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20010047031A1,O=C(C(F)CCc1ccccc1)N1CC[C@H](Sc2ccc(O)cc2)C1>>Oc1ccc(S[C@H]2CCN(CC(F)CCc3ccccc3)C2)cc1,,C1CCOC1,,CO,,test
US20070270422A1,COC(=O)c1ccc(Oc2ccc(N)cn2)c(F)c1.O=Cc1ccc(C(F)(F)F)cc1>>COC(=O)c1ccc(Oc2ccc(N=Cc3ccc(C(F)(F)F)cc3)cn2)c(F)c1,,CO,,,,test
US20070135416A1,BrCC1CC1.CC(C)N1CCC(Oc2ccc3c(c2)cc2n3CCNC2=O)CC1>>CC(C)N1CCC(Oc2ccc3c(c2)cc2n3CCN(CC3CC3)C2=O)CC1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20100152187A1,CCOC(=O)c1sc(N)nc1-c1ccccc1.O=C(Cl)c1ccccc1>>CCOC(=O)c1sc(NC(=O)c2ccccc2)nc1-c1ccccc1,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20110065681A1,CCCC[Sn](CCCC)(CCCC)c1ccc(C)cn1.COC(=O)c1cc(Br)cc(OC)c1>>COC(=O)c1cc(OC)cc(-c2ccc(C)cn2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20100227859A1,CC(C)[C@H](N)C(=O)OC(C)(C)C.O=S(=O)(Cl)c1ccc2c(c1)sc1ccc(Br)cc12>>CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)sc1ccc(Br)cc12)C(=O)OC(C)(C)C,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20090069288A1,O=C(Nc1ccc(CN2CC(C(=O)O)C2)cc1)OCc1ccccc1>>Nc1ccc(CN2CC(C(=O)O)C2)cc1,[Pd],CCO,,,,test
US20060247266A1,C=Cc1cncc2cccc(N)c12.CC(C)(C)OC(=O)N1CCCC(=O)C1>>C=Cc1cncc2cccc(NC3CCCN(C(=O)OC(C)(C)C)C3)c12,,CC(=O)O,ClCCCl,O=C([O-])O.[Na+],,test
US20060058282A1,CN(C)C(OC(C)(C)C)OC(C)(C)C.COC(=O)c1ccc(C2(C(=O)O)CCCCC2)cc1>>COC(=O)c1ccc(C2(C(=O)OC(C)(C)C)CCCCC2)cc1,,c1ccccc1,,,,test
US20020045628A1,COc1cc([N+](=O)[O-])c2ncccc2c1>>O=[N+]([O-])c1cc(O)cc2cccnc12,,Br,,[Na+].[OH-],,test
US20160024077A1,C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OC)c(C)cn3nc(-c4cccc(-c5c(O)cccc5F)c4)cc23)CC1.C=CC[C@@H](C)O>>C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OC)c(C)cn3nc(-c4cccc(-c5c(F)cccc5O[C@@H](C)CC=C)c4)cc23)CC1,,C1CCOC1,CCOCC,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120225867A1,CCOC(=O)c1coc(C2CCNCC2)n1.CS(=O)(=O)Cl>>CCOC(=O)c1coc(C2CCN(S(C)(=O)=O)CC2)n1,,ClCCl,,CCN(CC)CC,O,test
US20120202785A1,C[C@H](Nc1ncnc2[nH]cnc12)c1nc2ccc(F)cc2n1C1CC(OCc2ccccc2)C1>>C[C@H](Nc1ncnc2[nH]cnc12)c1nc2ccc(F)cc2n1C1CC(O)C1,,ClCCl,,BrB(Br)Br,,test
US06008230,CCOC(=O)c1cnc2c(NC(=O)c3c(Cl)cccc3Cl)cccc2c1Cl.Sc1ncc[nH]1>>O=C(Nc1cccc2c1ncc1c(=O)n3ccnc3sc12)c1c(Cl)cccc1Cl,,CN1CCCC1=O,,O,,test
US20040209901A1,Cc1cc(F)ccc1-c1nc(S(C)(=O)=O)nc2c1ccc(=O)n2-c1c(F)cccc1F.NCC(F)(F)F>>Cc1cc(F)ccc1-c1nc(NCC(F)(F)F)nc2c1ccc(=O)n2-c1c(F)cccc1F,,C1CCOC1,,,,test
US20130123289A1,COc1cccc(C(C)(C)C#N)n1>>CC(C)(C#N)c1cccc(=O)[nH]1,,C1COCCO1,,Cl,,test
US20090093507A1,CCOC(=O)CCCBr.O=C(Cc1cccc(O)c1)OCc1ccccc1>>CCOC(=O)CCCOc1cccc(CC(=O)OCc2ccccc2)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20090130090A1,COc1ccc(Br)cc1N=C=O.N>>COc1ccc(Br)cc1NC(N)=O,,C1CCOC1,,,,test
US04082535,BrBr.CCNc1nc(Cl)cc(NC2CC2)n1>>CCNc1nc(Cl)c(Br)c(NC2CC2)n1,,ClCCl,,N,O,test
US20150291573A1,CC1(S(=O)(=O)c2cccc(C(F)(F)F)c2)CCOC(COS(C)(=O)=O)C1.CS(=O)(=O)c1ccc(O)cc1F>>CC1(S(=O)(=O)c2cccc(C(F)(F)F)c2)CCOC(COc2ccc(S(C)(=O)=O)c(F)c2)C1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05977105,COc1ccc(-c2cccc(C#N)c2)cc1>>N#Cc1cccc(-c2ccc(O)cc2)c1,,ClCCl,,BrB(Br)Br,,test
US20090137585A1,CC(C)(C)OC(=O)NCCCC[C@H](CO)NC(=O)OCC1c2ccccc2-c2ccccc21.c1ccc(SSc2ccccc2)cc1>>CC(C)(C)OC(=O)NCCCC[C@H](CSc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc21,,Cc1ccccc1,,CCCCP(CCCC)CCCC,,test
US20080262230A1,CCOC(=O)CC(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1>>O=C(O)CC(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1,,CCO,,[Na+].[OH-],,test
US20140275568A1,CCOC(OCC)OCC.Cl.NC(=O)C(N)C(N)=O.O.O=S(=O)(O)O>>Cl.NC(=O)c1nc[nH]c1O.O.O,,CC(C)O,O,,,test
US05317016,COc1ccc(COC(=O)N2C[C@H](O)C[C@H]2COS(=O)(=O)c2ccc(C)cc2)cc1.O=C1NC(=O)c2ccccc21>>COc1ccc(COC(=O)N2C[C@H](O)C[C@H]2CN2C(=O)c3ccccc3C2=O)cc1,,CCOC(C)=O,CN(C)C=O,[K],,test
US20080300242A1,COc1cc([N+](=O)[O-])c(OC)cc1N1CCC(N2CCCCC2)CC1>>COc1cc(N2CCC(N3CCCCC3)CC2)c(OC)cc1N,[Pt],CCO,,CCOC(C)=O,,test
US20030166639A1,CC(C)CN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3ccnc(COC4CCCCO4)c3)c2)cc1Cl>>CC(C)CN(C)c1cc2c(cc1Cl)NC(=O)CC(c1cccc(-c3ccnc(CO)c3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US03930836,CCS(=O)(=O)Cl.OCCBr>>CCS(=O)(=O)OCCBr,,CCN(CC)CC,,CCOCC,,test
US20150266881A1,CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(C(=O)O)cc1.Nc1ccc(-c2ncccn2)cc1>>CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(C(=O)Nc2ccc(-c3ncccn3)cc2)cc1,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110144153A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(c1ccc(Br)cc1)C1CC1>>CC(C)(C)OC(=O)NC(c1ccc(Br)cc1)C1CC1,,CCN(CC)CC,,C1CCOC1,,test
US20080287434A1,CNCc1ccc(Cl)c(Cl)c1.O=C(CCc1ccccc1)NCCCBr>>CN(CCCNC(=O)CCc1ccccc1)Cc1ccc(Cl)c(Cl)c1,,ClCCl,,,,test
US20120232051A1,COc1cc(F)c(F)cc1-c1ccncc1NCC(F)(F)F.O=C(Cl)c1cc(F)cc(C(F)(F)F)c1>>COc1cc(F)c(F)cc1-c1ccncc1N(CC(F)(F)F)C(=O)c1cc(F)cc(C(F)(F)F)c1,,CCCCCCC,CCOC(C)=O,,,test
US20080051418A1,C1CCOC1.CC(C)Oc1ccc(C(=O)O)c(Cl)n1>>COC(=O)c1ccc(OC(C)C)nc1Cl,,C1CCOC1,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20080070864A1,CC(c1nc2ccccc2c(=O)n1-c1ccc(O)cc1)N(C)S(=O)(=O)c1ccc(C(C)(C)C)cc1.OCc1ccccc1>>CC(c1nc2ccccc2c(=O)n1-c1ccc(OCc2ccccc2)cc1)N(C)S(=O)(=O)c1ccc(C(C)(C)C)cc1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110166163A1,COC(=O)CCCCCNc1ncnc2oc(-c3ccccc3)c(B3OC(C)(C)C(C)(C)O3)c12.O=Cc1ccc(Br)nc1>>COC(=O)CCCCCNc1ncnc2oc(-c3ccccc3)c(-c3ccc(C=O)cn3)c12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CS(C)=O,,CO,O=C([O-])[O-].[K+].[K+],test
US20100022598A1,CON(C)C(=O)c1ccc(-c2ccc(F)cn2)cc1.C[Mg]Br>>CC(=O)c1ccc(-c2ccc(F)cn2)cc1,,C1CCOC1,,,,test
US20160221994A1,CC(C)(C)OC(=O)NCC1Oc2c(Cl)cc(Br)cc2C1O>>CC(C)(C)OC(=O)NCC1Oc2c(Cl)cc(Br)cc2C1=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20160031868A1,CCOc1nc2c(C(O)c3ccc(F)cn3)cc(-c3c(C)noc3C)cc2n1C(=O)OC(C)(C)C.Fc1ccc(Br)nc1>>Cc1noc(C)c1-c1cc(C(O)(c2ccc(F)cn2)c2ccc(F)cn2)c2[nH]c(=O)[nH]c2c1,,C1CCOC1,Cc1ccccc1,CC(C)[Mg]Cl,Cl,test
US20140193334A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)CNCCNc1c2ccccc2nc2ccccc12>>CC(C)(C)OC(=O)N(CCNc1c2ccccc2nc2ccccc12)CC(=O)O,,ClCCl,,CCN(CC)CC,,test
US04010273,COC(=O)c1cc([N+](=O)[O-])c(Oc2ccccc2)c(S(N)(=O)=O)c1>>COC(=O)c1cc(N)c(Oc2ccccc2)c(S(N)(=O)=O)c1,[Ni],CO,,CC(C)=O,,test
US20130172292A1,COCCn1c(S(C)(=O)=O)nc2cccnc21.Oc1ccc(-c2nn(CC(F)F)c3cccnc23)cc1>>COCCn1c(Oc2ccc(-c3nn(CC(F)F)c4cccnc34)cc2)nc2cccnc21,,CN(C)C=O,,O,[H-].[Na+],test
US20050288283A1,CCN(CC)CCC1CCN(C(=O)Cc2ccc3c(c2)/C(=C\CCN(C)C)c2ccccc2CO3)CC1.O=C(O)/C=C/C(=O)O>>CCN(CC)CCC1CCN(C(=O)Cc2ccc3c(c2)/C(=C\CCN(C)C)c2ccccc2CO3)CC1.O=C(O)/C=C/C(=O)O,,CO,,,,test
US20070208007A1,CCCN(CCC)CCCCNCc1ccc(CN(Cc2ncc[nH]2)Cc2nccn2C)cc1.NC=O>>CCCN(CCC)CCCCN(C=O)Cc1ccc(CN(Cc2ncc[nH]2)Cc2nccn2C)cc1,,CCO,,O=CO,,test
US04461640,COC(=O)C1=C(S(=O)(=O)N=C=O)CCC1.COc1nc(N)nc(OC)n1>>COC(=O)C1=C(S(=O)(=O)NC(=O)Nc2nc(OC)nc(OC)n2)CCC1,,CC#N,,,,test
US20050203078A1,COC(=O)c1ccc(N2CCOCCC2=O)c(C)c1>>Cc1cc(C(=O)O)ccc1N1CCOCCC1=O,,CCO,,O,[Li+].[OH-],test
US20060030600A1,COCC(COC)Oc1cc(-c2ccccc2Cl)c(N(C)C(=O)C(C)(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cn1>>CN(C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnc(OC(CO)CO)cc1-c1ccccc1Cl,,ClCCl,,BrB(Br)Br,,test
US20120276018A1,Fc1ccc(CCBr)cc1.O=C(N[C@H]1CN2CCC1CC2)OC(c1cccc(F)c1)c1cccc(F)c1>>O=C(N[C@H]1C[N+]2(CCc3ccc(F)cc3)CCC1CC2)OC(c1cccc(F)c1)c1cccc(F)c1.[Br-],,CCOC(C)=O,,,,test
US20140200216A1,COC(=O)N[C@H]1[C@@H](C)CN(c2ccncc2N)C[C@H]1NC(=O)OC(C)(C)C.O=C(Nc1cc2ccc(Br)cc2nc1C(=O)O)OCc1ccccc1>>COC(=O)N[C@H]1[C@@H](C)CN(c2ccncc2NC(=O)c2nc3cc(Br)ccc3cc2NC(=O)OCc2ccccc2)C[C@H]1NC(=O)OC(C)(C)C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160075657A1,COc1c(OCc2ccccc2)ccc2c1CCN(C(=O)OC(C)(C)C)C2>>COc1c(O)ccc2c1CCN(C(=O)OC(C)(C)C)C2,[Pd],C1CCOC1,,,,test
US20120142717A1,CSc1nc(=O)c(Cc2ccc(Cl)nc2)c[nH]1.NCCc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cc1>>O=c1nc(NCCc2ccc(Oc3ccc(Cl)c(C(F)(F)F)c3)cc2)[nH]cc1Cc1ccc(Cl)nc1,,CCO,,,,test
US20070265458A1,CCCC(=O)Cl.OC[C@@H](O)CCl>>CCCC(=O)OC[C@@H]1CO1,,CCN(CC)CC,,ClCCl,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20030073836A1,Cn1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1C(=O)O.NCCc1ccc(OCc2ccccc2)cc1>>CN(Cc1ccc(OCc2ccccc2)cc1)C(=O)c1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cn1C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20110245477A1,C=CCCCCCCO.COc1ccc(CCl)cc1>>C=CCCCCCCOCc1ccc(OC)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20050119295A1,COC(=O)CCCCn1nc2c(c1-c1ccc(Cl)cc1)CCNCC2>>O=C(O)CCCCn1nc2c(c1-c1ccc(Cl)cc1)CCNCC2,,C1CCOC1,CO,[Na+].[OH-],,test
US20060189650A1,CS(=O)(=O)c1ccc(S(=O)(=O)CCC2CCNCC2)cc1.O=C(CCCl)c1ccccc1>>CS(=O)(=O)c1ccc(S(=O)(=O)CCC2CCN(CCC(=O)c3ccccc3)CC2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090018103A1,O=C(OCc1ccccc1)N1CCC2OC2C1.[N-]=[N+]=[N-]>>[N-]=[N+]=N[C@@H]1CN(C(=O)OCc2ccccc2)CC[C@H]1O,,CO,O,[Cl-].[NH4+],,test
US04017633,CC(=O)c1c(O)oc(=O)c(C(C)=O)c1O.Nc1ccccc1O>>CC(=O)C1=C(O)C(=C(C)Nc2ccccc2O)C(=O)OC1=O,,CO,,,,test
US20040229862A1,COc1ccc(N2CCOCC2)c2sc(C(=O)O)nc12.c1c[nH]cn1>>COc1ccc(N2CCOCC2)c2sc(C#N)nc12,,CCOC(C)=O,c1ccncc1,O=P(Cl)(Cl)Cl,,test
US20080194565A1,CC(C)(C)OC(=O)C(CCn1nnc2ccccc2c1=O)C(O)CCc1ccc(-c2ccccc2)cc1>>O=C(O)C(CCn1nnc2ccccc2c1=O)C(O)CCc1ccc(-c2ccccc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160023991A1,CCOC(=O)CCCCOc1ccccc1CN(C(=O)c1ccc(-c2ccco2)cc1)C(C)C>>CC(C)N(Cc1ccccc1OCCCCC(=O)O)C(=O)c1ccc(-c2ccco2)cc1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20100240692A1,CCO.Cc1cc(Cl)c2ccc3cccnc3c2n1>>CCOc1cc(C)nc2c1ccc1cccnc12,,CCO,,C,C[O-].[Na+],test
US20150111882A1,CCOC(=O)C1CC(=O)c2ccsc2C1>>O=C1CC(C(=O)O)Cc2sccc21,,CCO,,[Na+].[OH-],,test
US20150274725A1,COc1cc(Br)c(F)cc1O.COc1ccc(CCl)cn1>>COc1ccc(COc2cc(F)c(Br)cc2OC)cn1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US04009175,CCN(O)CC.ClCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2>>CCN(CC)Cc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2,,CN(C)C=O,,[H-].[Na+],,test
US05688946,CC(C)(C)OC(=O)n1cnc(C[C@H](NC(=O)[C@H](Cc2ccccc2)CS(=O)(=O)C(C)(C)C)C(=O)N[C@@H](CC2CCCCC2)[C@@H](O)[C@@H](F)C2CC2)c1>>CC(C)(C)S(=O)(=O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](F)C1CC1,,CO,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20070111995A1,CCOC(=O)c1cnc2c(cnn2CC)c1N[C@H]1CC[C@@H](C(N)=O)CC1>>CCn1ncc2c(N[C@H]3CC[C@@H](C(N)=O)CC3)c(C(=O)O)cnc21,,CCO,,[Na+].[OH-],,test
US20030109626A1,C=CC(=O)NC(C)(C)CO.FC(F)=C(F)C(F)(F)F>>C=CC(=O)NC(C)(C)COC(F)(F)C(F)C(F)(F)F,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110275638A1,CN(C)C(On1nnc2ccc(Cl)cc21)=[N+](C)C.CNCCc1ccccc1.O=C(N[C@@H](CCc1ccc(O)cc1)C(=O)O)OCc1ccncc1>>CN(CCc1ccccc1)C(=O)[C@H](CCc1ccc(O)cc1)N(Cc1ccncc1)C(=O)O.Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20060223761A1,COC(=O)[C@@H](N)Cc1ccccc1.COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)N.C[C@H](NC(=O)OC(C)(C)C)C(=O)O.ClCCl>>CCCCCC=CCCC(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC,,ClCCl,,,,test
US20050014724A1,Nc1ccc(Br)c(C(F)(F)F)c1.OB(O)c1ccccc1>>Nc1ccc(-c2ccccc2)c(C(F)(F)F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06642395B1,CO.O=C(O)[C@H](O)c1ccccc1>>COC(=O)[C@H](O)c1ccccc1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05952362,CO.Cc1c(CC#N)cccc1NS(C)(=O)=O>>Cc1c(CC=O)cccc1NS(C)(=O)=O,,C1CCOC1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20130029972A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COC(=O)Cc1ccccc1Br>>COC(=O)Cc1ccccc1B1OC(C)(C)C(C)(C)O1,,CN1CCCC1=O,,C1COCCO1,CC(=O)[O-].[K+],test
US05621010,CC(C)(C)c1cc(C=Cc2ccccc2N)cc(C(C)(C)C)c1O.CCCCCCCC(=O)O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CCCCCCCNC(=O)Nc1ccccc1C=Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1,,Cc1ccccc1,,CCN(CC)CC,,test
US05621133,CCOC(=O)C1(Cc2cccc(OC)c2OC)CCCCCC1>>COc1cccc(CC2(CO)CCCCCC2)c1OC,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060247245A1,CCCc1nc(N)cnc1Cn1ccnc1-c1cccc(F)n1.O=CCCl>>CCCc1nc(Cl)cnc1Cn1ccnc1-c1cccc(F)n1,,CN(C)C=O,O,CCOC(C)=O,,test
US06063804,CC1=C(C)Cc2c(-c3ccccc3)[nH]c(-c3ccccc3)c2C1>>CC1Cc2c(-c3ccccc3)[nH]c(-c3ccccc3)c2CC1C,[Pd],CCO,,O=C[O-].[NH4+],,test
US04074046,CC(=O)Oc1ccccc1[N+](=O)[O-]>>Cc1nc2ccccc2o1,[Pd],,,CC(=O)OC(C)=O,,test
US20130102576A1,COC(=O)Cn1c(=O)oc2cc(N(C(=O)OC(C)(C)C)S(C)(=O)=O)ccc21>>CC(C)(C)OC(=O)N(c1ccc2c(c1)oc(=O)n2CC(=O)O)S(C)(=O)=O,,C1CCOC1,,Cl,[Li+].[OH-],test
US20150336949A1,C[C@H]1CO1.Cc1ccc(S(=O)(=O)n2cc(-c3cnn(Cc4cccc(F)c4)c3)c3cc(-c4ccc(C5CCNCC5)cc4)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3cnn(Cc4cccc(F)c4)c3)c3cc(-c4ccc(C5CCN(C[C@H](C)O)CC5)cc4)cnc32)cc1,,CCO,,CCN(C(C)C)C(C)C,Cl,test
US04197296,C/C=C1/CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@@H](OCC)C[C@]4(C)[C@H]3C(=NO)C[C@]12C>>C/C=C1/CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@@H](OCC)C[C@]4(C)[C@H]3[C@H](N)C[C@]12C,,CCCO,,O,,test
US20100087427A1,CC(=O)c1ccccc1.COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2N)C(C)C)ccc1OC>>COCCCOc1cc(C(=O)N(C[C@H]2CNC[C@@H]2NC(C)c2ccccc2)C(C)C)ccc1OC,,O,,CC#N,CC#N,test
US20150175570A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1nc(N2CCN[C@H](C)C2)ccc1[N+](=O)[O-]>>Cc1nc(N2CCN(C(=O)OC(C)(C)C)[C@H](C)C2)ccc1[N+](=O)[O-],,C1CCOC1,CCN(CC)CC,,,test
US20110053909A1,CN(C)C=O.Cc1c(Br)cccc1CCO[Si](C)(C)C(C)(C)C>>Cc1c(C=O)cccc1CCO[Si](C)(C)C(C)(C)C,,C1CCOC1,,[Li]CCCC,,test
US20090318504A1,COc1cccc(Nc2cc(N(C)C)nc(N3CCNCC3)n2)c1.O=C(O)c1cccs1>>COc1cccc(Nc2cc(N(C)C)nc(N3CCN(C(=O)c4cccs4)CC3)n2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US04551460,O=C(CCCCCBr)OCc1ccccc1.c1c[nH]cn1>>CCCCC(C(=O)OCc1ccccc1)n1ccnc1,,CN(C)C=O,,[H-].[Na+],,test
US20110166182A1,COc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(OS(=O)(=O)C(F)(F)F)ccc2c1.Cl>>COc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(OS(=O)(=O)C(F)(F)F)ccc2c1.Cl,,ClCCl,,CCOCC,,test
US20110263588A1,CCOC(=O)C(=O)C1C(=O)c2ccccc2OC1(C)C.CNN>>CCOC(=O)c1nn(C)c2c1C(C)(C)Oc1ccccc1-2,,CC(=O)O,,,,test
US20130116243A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)-n3c(n[nH]c3=O)CO4)cc2)CCC1.CI>>Cn1nc2n(c1=O)-c1cc(-c3ccccc3)c(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)nc1OC2,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US06020078,CC1(C)CCN2CCC(C)(C)c3c(O)c(C=O)cc1c32.CCOC(=O)Cc1nc2ccccc2s1>>CC1(C)CCN2CCC(C)(C)c3c2c1cc1cc(-c2nc4ccccc4s2)c(=O)oc31,,CC#N,,C1CCNCC1,,test
US20090326246A1,CS(=O)(=O)O[C@H]1CCN(Cc2ccccc2)C1.N>>N[C@@H]1CCN(Cc2ccccc2)C1,,CO,,,,test
US05246948,O=C1c2ccccc2C(=O)N1CCSc1ccncc1>>O=C1c2ccccc2C(O)N1CCSc1ccncc1,,CCO,,[BH4-].[Na+],,test
US20060058295A1,C1COCCN1.O=Cc1cnc2ccc(Br)cn12>>Brc1ccc2ncc(CN3CCOCC3)n2c1,,Cc1ccccc1,,CC(=O)O,[BH4-].[Na+],test
US20070244092A1,CC(C)(C)OC(=O)NC1CN(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCOCC2)C1>>CC(C)(C)c1nc2cc(S(=O)(=O)N3CC(N)C3)ccc2n1CC1CCOCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140274703A1,COC(=O)c1nc(-c2ccc(Cl)nc2Cl)cc(N)c1Cl>>Nc1cc(-c2ccc(Cl)nc2Cl)nc(C(=O)O)c1Cl,,CO,,[Na+].[OH-],,test
US20040248854A1,CCCCCC(=O)CP(=O)(OC)OC.COC(=O)CCCC#CCN1C(=O)CCCC1C=O>>CCCCCC(=O)/C=C/C1CCCC(=O)N1CC#CCCCC(=O)OC,,C1CCOC1,,[H-].[Na+],,test
US20140178304A1,COCC1CO1.c1ccc(-n2cccn2)cc1>>COCC(O)Cc1ccnn1-c1ccccc1,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US20130338140A1,CC(C)(C)[Si](C)(C)OC[C@@H](NC(=O)N1CCc2cnc(NC3CCOCC3)nc2C1)c1ccc(F)c(Cl)c1>>O=C(N[C@H](CO)c1ccc(F)c(Cl)c1)N1CCc2cnc(NC3CCOCC3)nc2C1,,O,,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05550134,CN1C(=O)CCC2(C)c3ccc(C(=O)O)cc3CCC12.OC(c1ccccc1)c1ccccc1>>CN1C(=O)CC[C@]2(C)c3ccc(C(=O)OC(c4ccccc4)c4ccccc4)cc3CC[C@@H]12,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US05122354,N[C@@H](Cc1c[nH]cn1)C(=O)O.OO>>N[C@@H](Cc1c[nH]cn1)C(=O)O.OO,,O,,,,test
US20060074084A1,COc1cccc(-c2c(C(=O)O)[nH]c3ccc(NS(=O)(=O)c4ccc(C(C)(C)C)cc4)cc23)c1.NC1CCOCC1>>COc1cccc(-c2c(C(=O)NC3CCOCC3)[nH]c3ccc(NS(=O)(=O)c4ccc(C(C)(C)C)cc4)cc23)c1,,CO,ClCCl,,,test
US20160016908A1,CCOC(=O)c1ccc2c(c1)[C@H](NC(=O)OCc1ccccc1)[C@@H](C)[C@H](CC)N2C(C)=O>>CCOC(=O)c1ccc2c(c1)[C@H](N)[C@@H](C)[C@H](CC)N2C(C)=O,[Pd],CCO,,,,test
US20040229900A1,N#Cc1ccc(OCCCBr)cc1.O=C1NC(=O)c2ccccc21>>N#Cc1ccc(OCCCN2C(=O)c3ccccc3C2=O)cc1,,CN(C)C=O,,[K],,test
US05972951,Cc1cc(C(=O)NCC(C)C2OCCO2)ccc1Br>>Cc1cnc(-c2ccc(Br)c(C)c2)o1,,O,,,,test
US06057357,CN(C(=O)Cc1coc2ccccc12)[C@H](CN1CCCC1)c1cccc(OCC(=O)OC(C)(C)C)c1>>CN(C(=O)Cc1coc2ccccc12)[C@H](CN1CCCC1)c1cccc(OCC(=O)O)c1,,ClCCl,,Cl,,test
US20150259359A1,CC1CC(=O)N(C[C@H]2CN(C(=O)OC(C)(C)C)[C@H](C)CN2Cc2ccccc2)C1>>CC1CC(=O)N(C[C@H]2CN(C(=O)OC(C)(C)C)[C@H](C)CN2)C1,[Pd],CCO,,CC(=O)O,,test
US20110040094A1,CCOC(=O)C(CC(C)C)c1ccc(OCc2ccccc2)cc1>>CCOC(=O)C(CC(C)C)c1ccc(O)cc1,[Pd],CO,,,,test
US20120214735A1,CC(C)(C)OC(=O)c1cccc(O)c1.O=[N+]([O-])c1ccc(Br)cn1>>CC(C)(C)OC(=O)c1cccc(Oc2ccc([N+](=O)[O-])nc2)c1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020193367A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(OCC(F)(F)F)c(I)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1cc(OCC(F)(F)F)c(I)cc1[N+](=O)[O-],,ClCCl,,O=C(O)C(F)(F)F,,test
US20040142850A1,CCOC(=O)N(Cc1ccc(Cl)cc1)c1c(N)cc(N)cc1C(F)(F)F>>Nc1cc(C(F)(F)F)c2c(c1)[nH]c(=O)n2Cc1ccc(Cl)cc1,,CCO,,[H-].[Na+],,test
US20100331360A1,CCC1(C(=O)[O-])CCCN(C(=O)OC(C)(C)C)C1.CI>>CCOC(=O)C1(C)CCCN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20090275578A1,CC(N)c1ccc(Oc2ccccc2)cc1.COC(=O)c1ccccc1CBr>>CC(c1ccc(Oc2ccccc2)cc1)N1Cc2ccccc2C1=O,,Cc1ccccc1,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US05371096,COC(=O)CC/C=C\CC[C@H]1[C@@H](c2cccnc2)OC[C@@H]1OCc1ccc(-c2ccccc2)cc1>>O=C(O)CC/C=C\CC[C@H]1[C@@H](c2cccnc2)OC[C@@H]1OCc1ccc(-c2ccccc2)cc1,,CO,,[Na+].[OH-],,test
US20070249670A1,CCOc1oc(-c2ccc(OC)cc2)nc1C(N)=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)c1nc(-c2ccc(OC)cc2)sc1N,,C1CCOC1,,,,test
US20140051676A1,CCOC(=O)C(=O)Cl.N=C(NO)c1nc(N)nc(Nc2cccc(F)c2)n1>>CCOC(=O)c1nc(-c2nc(N)nc(Nc3cccc(F)c3)n2)no1,,ClCCl,c1ccncc1,Cc1ccccc1,Cl,test
US20080280892A1,Nc1ccccc1Br.O=C(Cl)C=Cc1ccccc1>>O=C(/C=C/c1ccccc1)Nc1ccccc1Br,,CC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20120208827A1,CC1(C)OB(c2ccc3occc3c2)OC1(C)C.O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(Br)cc3)nc3ccccc32)C1>>O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(-c4ccc5occc5c4)cc3)nc3ccccc32)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,CO,O,O=C([O-])[O-].[Na+].[Na+],test
US20160264552A1,C=CC(=O)Nc1ccc(CNC(=O)[C@@H]2C[C@H](Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)CN(C(=O)OC(C)(C)C)C2)cc1>>C=CC(=O)Nc1ccc(CNC(=O)[C@H]2CNC[C@@H](Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)C2)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US04935430,Cc1cc(Cl)c([N+](=O)[O-])c(C)n1.N#Cc1ccc(N)cc1>>Cc1cc(Nc2ccc(C#N)cc2)c([N+](=O)[O-])c(C)n1,,CCO,,,,test
US04207318,COC(=O)c1cn2c(n1)COc1ccc(Cl)cc1-2>>O=C(O)c1cn2c(n1)COc1ccc(Cl)cc1-2,,CCO,O,[Na+].[OH-],,test
US06153634,COc1cc[nH]c1/C=C1\C(=O)Nc2ccc([N+](=O)[O-])c(F)c21.C[Si](C)(C)N=[N+]=[N-]>>COc1cc[nH]c1/C=C1\C(=O)Nc2ccc([N+](=O)[O-])c(N=[N+]=[N-])c21,,C1CCOC1,CCO,CCN(C(C)C)C(C)C,Cl,test
US20110251190A1,COc1cccc(Nc2ccc3c(c2)[C@@]2(COC(N)=N2)c2cc(O)cc(F)c2O3)c1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1cccc(Nc2ccc3c(c2)[C@@]2(COC(N)=N2)c2cc(OS(=O)(=O)C(F)(F)F)cc(F)c2O3)c1,,ClCCl,,CCN(CC)CC,,test
US20110082136A1,COC(=O)c1nc(Cl)ccc1C.O=C1CCC(=O)N1Br>>COC(=O)c1nc(Cl)ccc1CBr,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20090253677A1,CCOC(=O)c1nc2n(c(=O)c1O)CC1CCC2(NC(=O)OCc2ccccc2)CC1>>CCOC(=O)c1nc2n(c(=O)c1O)CC1CCC2(N)CC1,[Pd],CCO,,Cl,[H][H],test
US20140031360A1,Cc1ccc(S(=O)(=O)Cl)cc1.Fc1cccc(F)c1-c1ccc2[nH]cc(I)c2n1>>Cc1ccc(S(=O)(=O)n2cc(I)c3nc(-c4c(F)cccc4F)ccc32)cc1,,C1CCOC1,CCOC(C)=O,[Na+].[OH-],,test
US20160002251A1,CCOC(=O)C(C)(C)Br.NNc1ccccc1.O=Cc1cccc(F)c1F>>CCOC(=O)C(C)(C)N(N=Cc1cccc(F)c1F)c1ccccc1,,CO,,CCN(C(C)C)C(C)C,,test
US20070293677A1,CCN=C=O.CN(C)CCCNC(=O)[C@@H]1C[C@@H]2c3cccc4c3c(cn4C(=O)OC(C)(C)C)C[C@H]2N(C(=O)OC(C)(C)C)C1>>CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@@H]2c3cccc4c3c(cn4C(=O)OC(C)(C)C)C[C@H]2N(C(=O)OC(C)(C)C)C1,Cl[Cu],ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20160194284A1,CC(C)c1ccccc1N.O=C(Nc1ccc(Cl)cc1)Nc1cccc(-c2cccc(N3CCCC3)n2)c1>>CC(C)c1ccccc1NC(=O)Nc1cccc(-c2cccc(N3CCCC3)n2)c1,,CN(C)C=O,,CCN(CC)CC,,test
US05378720,CC(C)c1cc(O)cc2c1C(=O)N(CSc1ccccc1)S2(=O)=O.O=S(=O)(Cl)Cl>>CC(C)c1cc(O)cc2c1C(=O)N(CCl)S2(=O)=O,,ClCCl,,,,test
US20110076292A1,CC(C)n1ncnc1-c1cn2c(n1)-c1ccc(O)cc1OCC2.C[C@@H](O)C(=O)OC(C)(C)C>>CC(C)n1ncnc1-c1cn2c(n1)-c1ccc(O[C@@H](C)C(=O)OC(C)(C)C)cc1OCC2,,ClCCl,,CO,,test
US20080280876A1,CC(C)Oc1ccc(-c2noc(-c3ccc(S(=O)(=O)NCC(=O)OC(C)(C)C)cc3)n2)cc1Cl>>CC(C)Oc1ccc(-c2noc(-c3ccc(S(=O)(=O)NCC(=O)O)cc3)n2)cc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050032650A1,CCS.NS(=O)(=O)c1c(C(F)(F)F)nc2ccc(Cl)nn12>>CCSc1ccc2nc(C(F)(F)F)c(S(N)(=O)=O)n2n1,,CC(C)(C)O,,CC(C)(C)[O-].[K+],,test
US05990105,C=O.CNc1cc(Br)cc(Sc2ccc([N+](=O)[O-])cc2)c1>>CN(C)c1cc(Br)cc(Sc2ccc([N+](=O)[O-])cc2)c1,,CC#N,,CC(=O)O,[BH3-]C#N.[Na+],test
US04451463,CCCN=C(N)Nc1ccnc(S(C)=O)n1.OCCCO>>CCCN=C(N)Nc1ccnc(OCCCO)n1,,O,,[H-].[Na+],,test
US06358973B1,COc1cccc(C(C#N)CC(C)C)c1>>COc1cccc(C(CN)CC(C)C)c1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05597832,Brc1cscc1Br.CCCI>>CCCc1scc(Br)c1Br,,C1CCOC1,CCCCCC,CC(C)NC(C)C,,test
US20050124617A1,CC(C)c1ccccc1N=C1N=CC(C)(C)CS1.CCI>>CCN1CC(C)(C)CSC1=Nc1ccccc1C(C)C,,CN(C)C=O,,O,[H-].[Na+],test
US06251900B1,Clc1cc(Cl)nc(Cl)n1.c1ccc2[nH]cnc2c1>>Clc1cc(Cl)nc(-n2cnc3ccccc32)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040209921A1,COC(=O)c1cc(C#N)ccc1CBr.Cc1cccnc1CNCc1ncccc1NC(=O)OC(C)(C)C>>COC(=O)c1cc(C#N)ccc1CN(Cc1ncccc1C)Cc1ncccc1NC(=O)OC(C)(C)C,,CC#N,,CCN(C(C)C)C(C)C,,test
US20070249670A1,COC(=O)[C@@H](NC(=O)c1ccc(C)cc1N)C1CCCCC1.Cc1cccc(C)c1N=C=O>>COC(=O)[C@@H](NC(=O)c1ccc(C)cc1NC(=O)Nc1c(C)cccc1C)C1CCCCC1,,c1ccncc1,,CCCCCC,CCOC(C)=O,test
US20040132769A1,CI.O=C(O)c1cc(I)ccc1Br>>COC(=O)c1cc(I)ccc1Br,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160039844A1,C=Cc1ccccc1B(O)O.CCOC(=O)c1cc2nc(C)c([C@H](OC(C)(C)C)C(=O)OCC)c(I)n2n1>>C=Cc1ccccc1-c1c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc2cc(C(=O)OCC)nn12,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20140170207A1,CCCCCCCCCCCCOC(=O)C(C)N(C)C.O=S(=O)(O)c1ccccc1>>CCCCCCCCCCCCOC(=O)C(C)N(C)C.O=S(=O)(O)c1ccccc1,,CCOC(C)=O,,,,test
US20030171418A1,C=CCc1c(OC(C)=O)ccc2cnn(C(=O)NCC)c12.O=C(OO)c1cccc(Cl)c1>>CCNC(=O)n1ncc2ccc(OC(C)=O)c(CC3CO3)c21,,ClCCl,,,,test
US20130336920A1,NCCN1CCOCC1.O=C(O)CCSCc1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1>>O=C(CCSCc1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1)NCCN1CCOCC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030191118A1,CCOC(=O)[C@H](Cc1ccc(-c2ccccc2OC)c(C(C)=O)c1)NC(=O)c1c(Cl)cccc1Cl>>CCOC(=O)[C@H](Cc1ccc(-c2ccccc2OC)c(C(C)O)c1)NC(=O)c1c(Cl)cccc1Cl,,CO,,[BH4-].[Na+],,test
US06562989B2,COC(=O)c1ccc(Cl)cc1.Cc1ccccc1B(O)O>>COC(=O)c1ccc(-c2ccccc2C)cc1,,C1CCOC1,,[F-].[K+],,test
US20030134859A1,Nc1ccc(NC(=O)c2cc([N+](=O)[O-])ccc2Cl)cc1>>Nc1ccc(NC(=O)c2cc([N+](=O)[O-])ccc2Cl)cc1,,O=C([O-])O,[Na+],Cl,O,test
US04410699,CC1=CC(C)(C(=N)N)N=N1.O=[N+]([O-])O.c1ccc2c(c1)CC1(CNCc3ccccc31)O2>>N=C(N)N1Cc2ccccc2C2(Cc3ccccc3O2)C1.O=[N+]([O-])O,,CCO,,,,test
US20120165347A1,CC(C)(C)S(=O)N=C1c2cc(Br)ccc2CC12CCC(F)(F)CC2>>N=C1c2cc(Br)ccc2CC12CCC(F)(F)CC2,,C1COCCO1,,CCOCC,Cl,test
US20130203815A1,CCOC(=O)C(C(=O)OCC)C(C[N+](=O)[O-])c1c(OC)cc(OC)cc1OC>>CCOC(=O)C1C(=O)NCC1c1c(OC)cc(OC)cc1OC,[Ni],CO,,,,test
US20050215603A1,CC(C)(C)OC(=O)N1C[C@@H](CN)C[C@H]1C(=O)N1CCSC1.N#Cc1cccc(C(=O)Cl)c1>>CC(C)(C)OC(=O)N1C[C@@H](CNC(=O)c2cccc(C#N)c2)C[C@H]1C(=O)N1CCSC1,,ClCCl,,CCN(CC)CC,,test
US20020128247A1,Cc1ccc(S(=O)(=O)OC[C@H](O[Si](C)(C)C(C)(C)C)c2ccc(Cl)nc2)cc1.NCCO>>CC(C)(C)[Si](C)(C)OC(CNCCO)c1ccc(Cl)nc1,,CS(C)=O,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20130035326A1,CC(C)(C)c1cc(N)no1.CC1(C)OB(c2ccc(CC(=O)O)cc2)OC1(C)C>>CC(C)(C)c1cc(NC(=O)Cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)no1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04941911,BrBr.COc1cnn(-c2cccc(C)c2)c(=O)c1OC>>COc1cnn(-c2cccc(CBr)c2)c(=O)c1OC,,ClCCl,O,CC(=O)[O-].[Na+],,test
US20160108026A1,Brc1cncc(Br)c1.NS(=O)(=O)c1ccc(B(O)O)cc1>>NS(=O)(=O)c1ccc(-c2cncc(Br)c2)cc1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20050070680A1,C[Zn]C.Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F>>Fc1c(F)c(F)c([Zn]c2c(F)c(F)c(F)c(F)c2F)c(F)c1F,,Cc1ccccc1,,,,test
US06002008,COc1cc2ncc(C#N)c(Cl)c2cc1OC.CSc1ccc(N)cc1>>COc1cc2ncc(C#N)c(Nc3ccc(SC)cc3)c2cc1OC,,CCOCCO,,Cl,c1ccncc1,test
US20110105461A1,CN.Cc1ccc(S(=O)(=O)OC[C@H]2COc3c(Cl)cc(S(C)(=O)=O)cc3O2)cc1>>CNC[C@H]1COc2c(Cl)cc(S(C)(=O)=O)cc2O1,,CC#N,,,,test
US20030162818A1,CC(=O)OC(C)=O.NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCc2ccc(Cl)cc2)c1>>CC(=O)NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCc2ccc(Cl)cc2)c1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20090075971A1,CC(C)(C)OC(=O)N[C@H]1COc2c(cccc2-c2ccccc2)NC1=O.Cl>>Cl.N[C@H]1COc2c(cccc2-c2ccccc2)NC1=O,,C1COCCO1,,,,test
US20080045521A1,COC(=O)[C@H](Cc1cccc(O)c1)NC(=O)c1c(Cl)cccc1Cl.OCCBr>>COC(=O)[C@H](Cc1cccc(OCCBr)c1)NC(=O)c1c(Cl)cccc1Cl,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20050014749A1,N#Cc1ccc2c(c1)CCCC2O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>N#Cc1ccc2c(c1)CCC[C@H]2N=[N+]=[N-],,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20140206681A1,CC(C)(O)c1ccnc(Cl)c1.CC1(C)OB(c2ccc(C(N)=O)cc2)OC1(C)C>>CC(C)(O)c1ccnc(NC(=O)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)c1,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110076292A1,CC(C)N(CCO)C(=O)c1cn2c(n1)-c1ccc(C3=CCN(C(=O)OC(C)(C)C)CC3)cc1OCC2.Cl>>CC(C)N(CCO)C(=O)c1cn2c(n1)-c1ccc(C3CCNCC3)cc1OCC2.Cl,[Pd],,,,,test
US20150252036A1,CC(=O)Oc1ccc(OC(C)C)c(Br)c1>>CC(C)Oc1ccc(O)cc1Br,,CO,O,Cl,[K+].[OH-],test
US20150353493A1,COc1cc2c(cc1OC)C(=O)/C(=C/c1ccncc1F)CC2>>COc1cc2c(cc1OC)C(=O)C(Cc1ccncc1F)CC2,[Pt],,,,,test
US20160194350A1,CC(C)(C)[Si](C)(C)OC[C@@H]1C[C@@H](O)[C@H](n2c(=O)sc3c(=O)[nH]c(N)nc32)O1>>CC(C)(C)[Si](C)(C)OC[C@@H]1CC(=O)[C@H](n2c(=O)sc3c(=O)[nH]c(N)nc32)O1,,C1CCOC1,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20150065482A1,Clc1cccc2[nH]ncc12.II>>Clc1cccc2[nH]nc(I)c12,,CN(C)C=O,,[K+].[OH-],,test
US20130184463A1,COC(=O)c1ccc2c(cnn2Cc2nc(C)ccc2OCC(C)C)c1>>Cc1ccc(OCC(C)C)c(Cn2ncc3cc(C(=O)O)ccc32)n1,,C1COCCO1,,[Na+].[OH-],,test
US20090170907A1,N#Cc1ccc(N(Cc2ccc(Br)o2)CC(F)(F)F)cc1C(F)(F)F.OB(O)c1cc(F)cc(F)c1>>N#Cc1ccc(N(Cc2ccc(-c3cc(F)cc(F)c3)o2)CC(F)(F)F)cc1C(F)(F)F,[Pd],CN(C)C=O,,O,O=C([O-])O.[Na+],test
US04490370,CCOC(=O)C(=NO)c1ccc2cc(OC)ccc2c1>>CCOC(=O)C(N)c1ccc2cc(OC)ccc2c1,[Zn],CO,,O=CO,,test
US20150018546A1,CCOC(=O)c1c(NCc2ccccn2)c2cncnc2n(OCc2ccccc2)c1=O>>O=c1cc(NCc2ccccn2)c2cncnc2n1OCc1ccccc1,,CO,,[Na+].[OH-],,test
US20080161317A1,NN.Oc1nc2ccc(Cl)nc2nc1-c1ccccc1>>NNc1ccc2nc(O)c(-c3ccccc3)nc2n1,,CCOC(C)=O,,C1COCCO1,,test
US20100120860A1,N#Cc1nnc(NC2CCNCC2)s1.O=Cc1cccc(C(F)(F)F)c1>>N#Cc1nnc(NC2CCN(Cc3cccc(C(F)(F)F)c3)CC2)s1,,CCOC(C)=O,CN(C)C=O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04946843,CCOC(=O)N1CCNCC1.OCCn1c(CCl)nc2cccnc21>>CCOC(=O)N1CCN(Cc2nc3cccnc3n2CCO)CC1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US07217730B2,CCCC1(CC(=O)OCC)OCCc2c1[nH]c1c(Cl)ccc(Cl)c21>>CCCC1(CC(=O)O)OCCc2c1[nH]c1c(Cl)ccc(Cl)c21,,CCO,,[Na+].[OH-],,test
US05441971,COCOCc1ccc(CCOc2ccc([N+](=O)[O-])cc2)nc1>>O=[N+]([O-])c1ccc(OCCc2ccc(CO)cn2)cc1,,CO,,Cl,,test
US07071201B2,CCOC(=O)Cc1cccnc1>>CC(O)c1cccnc1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20120149737A1,COc1cc(I)cc(OC)c1Cl>>Oc1cc(I)cc(O)c1Cl,,ClCCl,,BrB(Br)Br,O,test
US20160060257A1,COc1ccc(F)cc1-c1ccnc2c1cc(I)n2S(=O)(=O)c1ccc(C)cc1.O=C1CCS(=O)(=O)CC1>>COc1ccc(F)cc1-c1ccnc2c1cc(C1(O)CCS(=O)(=O)CC1)n2S(=O)(=O)c1ccc(C)cc1,,C1CCOC1,,[Li]CCCC,,test
US20120010228A1,CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCNCC3)C2=O)c1.ClCCCn1nnc2ccccc21>>CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(CCCn4nnc5ccccc54)CC3)C2=O)c1,,CCC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20090062356A1,CC(C)(C)OC(=O)Nc1cc(F)c(F)cc1N.O=C(O)COc1ccccc1Cl.O=CC1CCCCC1.[C-]#[N+]C1CCCCC1>>O=C(NC1CCCCC1)C(C1CCCCC1)n1c(COc2ccccc2Cl)nc2cc(F)c(F)cc21,,C1COCCO1,,CO,Cl,test
US20130053359A1,CN(C(=O)OC(C)(C)C)[C@@H]1CC[C@@H](OC(=O)C(O)(c2cccs2)c2cccs2)CC1>>CN[C@@H]1CC[C@@H](OC(=O)C(O)(c2cccs2)c2cccs2)CC1,,C1COCCO1,,Cl,,test
US20110251206A1,CCOc1c(Nc2ccc(Cl)c(S(=O)(=O)N(C)OC)c2O)c(=O)c1=O.CC[C@@H](N)C1CCCO1>>CC[C@@H](Nc1c(Nc2ccc(Cl)c(S(=O)(=O)N(C)OC)c2O)c(=O)c1=O)C1CCCO1,,CC#N,,,,test
US06258829B1,CCOC(=O)c1cc2c(nc1C)C(OC(C)=O)CCC2>>COC(=O)c1cc2c(nc1C)C(O)CCC2,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20010051633A1,CC(=O)N1CCC(C(=O)Cl)CC1.COc1ccccc1>>COc1ccc(C(=O)C2CCN(C(C)=O)CC2)cc1,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20060052424A1,CC(=O)OC(C)=O.O=C1CC[C@H](C(=O)O)N1.c1ccncc1>>O=C1CC[C@@H]2CO[C@@H](c3ccccc3)N12,,c1ccncc1,,,,test
US20130029971A1,CCOC(=O)CC1CCN(c2ncc(S(C)(=O)=O)cc2[N+](=O)[O-])CC1>>CCOC(=O)CC1CCN(c2ncc(S(C)(=O)=O)cc2N)CC1,[Pd],CCOC(C)=O,,CCO,,test
US06300325B1,O=[N+]([O-])c1cccc2nc(C(F)(F)F)[nH]c12>>Nc1cccc2nc(C(F)(F)F)[nH]c12,[Pd],CO,,,,test
US20070254866A1,CCOC(=O)c1cc(=O)c2c(F)c(F)c(NCCNc3ccccn3)c(F)c2n1C1CC1.COc1ccc(CN)cc1>>CCOC(=O)c1cc(=O)c2c(NCc3ccc(OC)cc3)c(F)c(NCCNc3ccccn3)c(F)c2n1C1CC1,,CS(C)=O,,CCN(CC)CC,O,test
US05968985,COC(=O)c1cc(OS(=O)(=O)C(F)(F)F)cc(C(=O)NCCN(C)C)c1>>COC(=O)c1cc(OS(=O)(=O)C(F)(F)F)cc(C(=O)NCCN(C)C)c1,,CCOC(C)=O,O,O=S(=O)(O)C(F)(F)F,,test
US20090203667A1,CCOC(=O)/C=C/C(C)=C(c1ccc(C(F)(F)F)cc1)c1ccc(C(F)(F)F)cc1>>CC(/C=C/C(=O)O)=C(c1ccc(C(F)(F)F)cc1)c1ccc(C(F)(F)F)cc1,,CO,,[Na+].[OH-],,test
US05753664,Cn1c(S)nc2[nH]ncc2c1=O.O=C(c1ccc(F)cc1)c1ccc(CBr)cc1>>Cn1c(SCc2ccc(C(=O)c3ccc(F)cc3)cc2)nc2[nH]ncc2c1=O,,CN(C)C=O,O,[K],,test
US20120083469A1,CCOC(=O)C(CCCCB1OC(C)(C)C(C)(C)O1)NCc1ccc(Cl)cc1.Cl>>Cl.O=C(O)C(CCCCB(O)O)NCc1ccc(Cl)cc1,,Cl,,,,test
US20150266857A1,NC(=O)CCc1nc2cc(-c3cn(S(=O)(=O)c4ccccc4)c4cc(F)ccc34)ccc2[nH]1>>NC(=O)CCc1nc2cc(-c3c[nH]c4cc(F)ccc34)ccc2[nH]1,,CCO,,Cl,[K+].[OH-],test
US20140350010A1,CC(=O)C1CCC1.COC(=O)C(=O)OC>>COC(=O)C(=O)CC(=O)C1CCC1,,CO,,C[O-].[Na+],,test
US20080009462A1,C=CCCCCCCCCCCCCCCOCCCO[Si](C)(C)C(C)(C)C>>C=CCCCCCCCCCCCCCCOCCCO,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110288116A1,CC(=O)OC1CCNC1Cc1c[nH]c2ncccc12.CC(C)(C)OC(=O)N[C@H](C(=O)O)C(C)(C)C>>CC(=O)OC1CCN(C(=O)C(NC(=O)OC(C)(C)C)C(C)(C)C)C1Cc1c[nH]c2ncccc12,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150274747A1,COC1COC2C(N=[N+]=[N-])COC12>>COC1COC2C(N)COC12,[Pd],CO,,,,test
US20140200216A1,CI.O=C(O)c1cc(F)c(Br)cc1[N+](=O)[O-]>>COC(=O)c1cc(F)c(Br)cc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090281107A1,CS(=O)(=O)Cl.OCC12CC3CC(CC(C3)C1)C2>>CS(=O)(=O)OCC12CC3CC(CC(C3)C1)C2,,ClCCl,,CCN(CC)CC,,test
US20090325964A1,O=C(Cl)c1cccc(CCl)c1.c1ccc(N2CCNCC2)nc1>>O=C(c1cccc(CCl)c1)N1CCN(c2ccccn2)CC1,,ClCCl,,,,test
US06369076B1,C1CCNC1.O=C1CCC(Cc2ccccc2)CC1>>C1=C(N2CCCC2)CCC(Cc2ccccc2)C1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04612317,COc1ccc(CCl)cc1.OCC1Cc2c([nH]c3ccccc23)CN1.S=C=S>>COc1ccc(CSC(=S)N2Cc3[nH]c4ccccc4c3CC2CO)cc1,,CS(C)=O,,CCN(CC)CC,,test
US20110251186A1,CCOC(=O)CC1(N=[N+]=[N-])c2cc(Br)ccc2Oc2cnc(Cl)cc21>>NC1(CCO)c2cc(Br)ccc2Oc2cnc(Cl)cc21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070185152A1,CC(C)(C)OC(=O)N[C@H](CO)CO[Si](C)(C)C(C)(C)C.Oc1cnc(Cl)c(Br)c1>>CC(C)(C)OC(=O)N[C@H](COc1cnc(Cl)c(Br)c1)CO[Si](C)(C)C(C)(C)C,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040002511A1,C=C(C)c1c(C)nn2ccccc12>>Cc1nn2ccccc2c1C(C)C,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20060148858A1,CC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCCO.CS(=O)(=O)Cl>>CC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCCOS(C)(=O)=O,,C1CCOC1,,CCN(CC)CC,,test
US20120329788A1,N#Cc1cnc(Cl)s1.Oc1ccc(C(F)(F)C(O)(Cn2cnnn2)c2ccc(F)cc2F)nc1>>N#Cc1cnc(Oc2ccc(C(F)(F)C(O)(Cn3cnnn3)c3ccc(F)cc3F)nc2)s1,,CS(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20090181956A1,O=C1CCC(=O)N1Br.O=Cc1cccn1-c1c(Cl)cccc1Cl>>O=Cc1cc(Br)cn1-c1c(Cl)cccc1Cl,,CN(C)C=O,,O,,test
US20030119813A1,COc1cc2c(cc1OC)-c1cc(Cl)nc(=O)n1CC2.Oc1c(Cl)cccc1Cl>>COc1cc2c(cc1OC)-c1cc(Oc3c(Cl)cccc3Cl)nc(=O)n1CC2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120208819A1,BrC1CCC1.Clc1ncnc2[nH]cc(I)c12>>Clc1ncnc2c1c(I)cn2C1CCC1,,CC(=O)N(C)C,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150232420A1,C=CC(=O)NCCCC[C@H](N)C(=O)N1CCN(c2cccc(C)n2)CC1.O=C(Cl)c1ccccc1>>C=CC(=O)NCCCC[C@H](NC(=O)c1ccccc1)C(=O)N1CCN(c2cccc(C)n2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20020173527A1,COC(=O)c1ccc(OC)c([N+](=O)[O-])c1N>>COC(=O)c1ccc(OC)c(N)c1N,[Pd],CCO,,[H][H],,test
US20020045615A1,CCN(CC)CC.COc1ccc(-c2csc(N)n2)c2sc(N)nc12.O=C(Cl)N1CCOCC1>>COc1ccc(-c2csc(C)n2)c2sc(NC(=O)N3CCOCC3)nc12,,C1COCCO1,O,[H-].[Na+],,test
US20140163000A1,CI.CN1CCN(c2ccncc2[N+](=O)[O-])CC1CO>>COCC1CN(c2ccncc2[N+](=O)[O-])CCN1C,,CN(C)C=O,,[H-].[Na+],,test
US20100305092A1,CCOC(=O)CC(=O)C1CCCO1.[N-]=[N+]=Nc1ccccc1F>>CCOC(=O)c1nnn(-c2ccccc2F)c1C1CCCO1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US05912247,CC(=O)O.C[C@H](O)[C@H](C)Oc1nc(N2CCNCC2)nc2ccccc12>>CC(=O)O.C[C@H](O)[C@H](C)Oc1nc(N2CCNCC2)nc2ccccc12,,CC(C)=O,,,,test
US20040063707A1,Fc1ccnc2[nH]ccc12.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(c1ccccc1)n1ccc2c(F)ccnc21,,CCOC(C)=O,,C1CCOC1,[Cl-].[NH4+],test
US20110301352A1,C=C1CN2CCC1CC2.CO.S>>OC1(CS)CN2CCC1CC2,,ClCCl,,,,test
US20150266895A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3cc(NC(=O)[O-])ncc23)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3cc(N)ncc23)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04091032,C(=NC1CCCCC1)=NC1CCCCC1.C1COCCO1.O=C1C2C3C=CC(C3)C2C(=O)N1O>>O=C(NC1CCCCC1)NC1CCCCC1.O=C1C2C3C=CC(C3)C2C(=O)N1O,,C1CCOC1,C1COCCO1,,,test
US20060040999A1,C[C@@H]1[C@@H](c2cc(C(F)(F)F)ccc2I)OC(=O)N1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=[N+]([O-])O>>C[C@@H]1[C@@H](c2cc(C(F)(F)F)cc([N+](=O)[O-])c2I)OC(=O)N1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1,,CCOC(C)=O,,O,,test
US04772600,NC(=O)CNc1ncccc1[N+](=O)[O-]>>NC(=O)CNc1ncccc1N,[Pd],CCOC(C)=O,,CC#N,,test
US20050181037A1,CC(C)(C)[Si](C)(C)Cl.O[C@@H]1CO[C@H](c2ccccc2)OC1>>CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@H](c2ccccc2)OC1,,CN(C)C=O,,O,c1c[nH]cn1,test
US20040138065A1,FC(F)(F)CCBr.N#CC(C#N)Cc1ccc(Br)cc1>>N#CC(C#N)(CCC(F)(F)F)Cc1ccc(Br)cc1,,CN(C)C=O,,[H-].[Na+],,test
US05595989,Br[Mg]C1CC1.O=c1c2ccccc2ccc2ccccc12>>OC1(C2CC2)c2ccccc2C=Cc2ccccc21,,C1CCOC1,O,[Cl-].[NH4+],,test
US20100261755A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Fc1cc(Br)cc(F)c1Cl>>CC1(C)OB(c2cc(F)c(Cl)c(F)c2)OC1(C)C,Cl[Pd]Cl,CCOC(C)=O,CS(C)=O,CC(=O)[O-].[K+],,test
US04956370,O=C=O.Oc1ccc(OC(F)(F)F)cc1>>O=C(O)c1cc(OC(F)(F)F)ccc1O,,O,,O=C([O-])[O-].[K+].[K+],,test
US20040005986A1,CCOC(=O)CP(=O)(OCC)OCC.O=C(C=NNc1ccc(Cl)cc1)C(F)(F)F>>O=c1cc(C(F)(F)F)cnn1-c1ccc(Cl)cc1,,CCN(CC)CC,,,,test
US20060276498A1,CC(C)c1cccc(Nc2c(C#N)cnc3cnc(F)cc23)c1.NCCN1CCOCC1>>CC(C)c1cccc(Nc2c(C#N)cnc3cnc(NCCN4CCOCC4)cc23)c1,,c1ccncc1,,,,test
US20090221645A1,CC[Mg]Br.COCNC(=O)c1cccc2c(Cl)cccc12>>CCC(=O)c1cccc2c(Cl)cccc12,,CO,,C1CCOC1,Cl,test
US20050239841A1,COc1ccc([C@@]23CC[C@@H](N)C[C@@H]2N(CC2CC2)CC3)cc1OC.Cl.O=C=Nc1ccc(F)c(F)c1>>COc1ccc([C@@]23CC[C@@H](NC(=O)Nc4ccc(F)c(F)c4)C[C@@H]2N(CC2CC2)CC3)cc1OC.Cl,,CCOCC,ClCCl,,,test
US20030216356A1,CC(C)(C)OC(=O)OC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)Nc1ccc(Oc2ccc3[nH]c(N)c(C#N)c3c2)cc1>>CC(C)(C)OC(=O)OC[C@H](N)C(=O)Nc1ccc(Oc2ccc3[nH]c(N)c(C#N)c3c2)cc1,,ClC(Cl)Cl,,C1CCNCC1,,test
US20050043537A1,CCOC(OCC)OCC.COc1cc(NC(=O)CC#N)c(Cl)cc1Cl.COc1ccc(N)cc1OCCCN1CCN(C)CC1>>COc1cc(NC(=O)C(C#N)=CNc2ccc(OC)c(OCCCN3CCN(C)CC3)c2)c(Cl)cc1Cl,,CC(C)O,,,,test
US20070135595A1,C1=CCC=C1.CC1=Cc2c(Br)cccc2C1[Si](C)(C)Cl>>CC1=Cc2c(Br)cccc2C1[Si](C)(C)C1C=CC=C1,,CCOCC,,O,[Li]CCCC,test
US20090124629A1,CS(=O)(=O)Cl.Cn1c(CCCCCO)nnc1-c1ccccc1>>Cn1c(CCCCCOS(C)(=O)=O)nnc1-c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20030055085A1,Fc1cc(Br)cc(-c2nc(-c3ccccn3)no2)c1.c1cncc(B2OCCCO2)c1>>Fc1cc(-c2cccnc2)cc(-c2nc(-c3ccccn3)no2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,ClC(Cl)Cl,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20100197678A1,C=CCn1cc(C=O)cc1C#N.C[Si](C)(C)C(F)(F)F>>C=CCn1cc(C(O)C(F)(F)F)cc1C#N,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100298343A1,BrP(Br)Br.OCc1ccc(-c2ccc(C(F)(F)F)cn2)cc1>>FC(F)(F)c1ccc(-c2ccc(CBr)cc2)nc1,,COCCOC,,O=C([O-])O.[Na+],,test
US20030181519A1,CC(=O)OC(C)=O.Nc1cccc2ccc(O)cc12>>CC(=O)Nc1cccc2ccc(O)cc12,,CO,,,,test
US20090270350A1,COc1ccc(Cn2c(C)cc(OCc3ccccc3CN3C(=O)c4ccccc4C3=O)c(Cl)c2=O)cc1Cl>>COc1ccc(Cn2c(C)cc(OCc3ccccc3CN)c(Cl)c2=O)cc1Cl,,CO,,NN,O,test
US05714489,COC(=O)CBr.O=c1[nH]c2cc(-n3cccc3)c(C(F)(F)F)cc2[nH]c1=O>>COC(=O)Cn1c(=O)c(=O)[nH]c2cc(C(F)(F)F)c(-n3cccc3)cc21,,CCOC(C)=O,ClCCl,,,test
US20060030612A1,CC(C)(O)c1cccc2c(-c3ccccc3)n(Cc3ccccc3)nc12>>C=C(C)c1cccc2c(-c3ccccc3)n(Cc3ccccc3)nc12,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05604181,CC(C)NC(C)C.COC(=O)C(c1ccccc1)c1nc(OC)cc(OC)n1.Cc1ccc(S(=O)(=O)C#N)cc1.[Li]CCCC>>CC(C)[N-]C(C)C.COC(=O)C(C#N)(c1ccccc1)c1nc(OC)cc(OC)n1.[Li+],,C1CCOC1,,[Cl-].[NH4+],,test
US20150322002A1,CC(C)COc1ncc(Oc2cc(F)c(C(=O)OC(C)(C)C)cc2Cl)cc1Cl>>CC(C)COc1ncc(Oc2cc(F)c(C(=O)O)cc2Cl)cc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120186446A1,Cc1nccn1C.OCC(O)CCl>>Cc1n(C)cc[n+]1CC(O)CO.[Cl-],,CCOCC,,,,test
US20110172224A1,O=S(Br)Br.OCCn1cc2c(n1)CCc1c-2sc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12>>Clc1cc(Nc2ncnc3sc4c(c23)CCc2nn(CCBr)cc2-4)ccc1OCc1ccccn1,,O,,ClCCl,,test
US20080058293A1,CCN(CCCc1ccc2c(NC(=O)C[C@@H](C)c3ccccc3)c(Cl)ccc2n1)C(=O)OC(C)(C)C.Cl.ClCCl>>CCNCCCc1ccc2c(NC(=O)C[C@@H](C)c3ccccc3)c(Cl)ccc2n1.Cl.Cl,,C1COCCO1,ClCCl,,,test
US04415572,Br.BrCCNCCBr.Nc1ccc2[nH]c(=O)ccc2c1>>Br.O=c1ccc2cc(N3CCNCC3)ccc2[nH]1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US06979736B2,CC(C)(C)OC(=O)CN1C(=O)[C@@H](N)CCc2ccccc21.CCOC(=O)C=CC(=O)c1ccccc1>>CC(C)(C)OC(=O)CN1C(=O)C(NC2CC(c3ccccc3)OC2=O)CCc2ccccc21,[Pd],Cc1ccccc1,,,,test
US20060199836A1,CCOC(=O)c1ncc2cc(C=Cc3ccccc3)sc2c1O>>CCOC(=O)c1ncc2cc(CCc3ccccc3)sc2c1O,[Pd],CCOC(C)=O,,CCO,,test
US20110190278A1,CC(C)(C)OC(=O)N1CC[C@H](c2cccc(OCc3ccccc3)c2)[C@@H](NC(=O)OCc2ccccc2)C1.CCI>>CCN(C(=O)OCc1ccccc1)[C@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1c1cccc(OCc2ccccc2)c1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20150232465A1,COC(=O)Cl.C[C@H]1CN(C(=O)OC(C)(C)C)c2cc(Br)ccc2N1>>COC(=O)N1c2ccc(Br)cc2N(C(=O)OC(C)(C)C)C[C@@H]1C,,ClCCCl,,c1ccncc1,,test
US20160229814A1,CCN1C(=O)C(C(C)C)Oc2cc([N+](=O)[O-])ccc21>>CCN1C(=O)C(C(C)C)Oc2cc(N)ccc21,[Pd],CO,,[H][H],,test
US20130143876A1,COC(=O)C(C)c1ccc(C2CCN(C(=O)OC(C)(C)C)CC2)cc1>>COC(=O)C(C)c1ccc(C2CCNCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06225320B1,O=C(OC(=O)C(F)(F)F)C(F)(F)F.O=[N+]([O-])c1cnc(Cl)c(Br)c1>>O=C(Nc1cnc(Cl)c(Br)c1)C(F)(F)F,O=[Pt],CCOC(C)=O,,[H][H],,test
US20080064681A1,C[C@H]1CN(C(=O)OC(C)(C)C)CCCCN1S(=O)(=O)c1cccc2cncc(Cl)c12.Cl.ClC(Cl)Cl>>C[C@H]1CNCCCCN1S(=O)(=O)c1cccc2cncc(Cl)c12.Cl.Cl,,ClC(Cl)Cl,,C1COCCO1,,test
US20060122222A1,COC(=O)c1cncc(OCc2ccc(-c3cccc(CN4CCCc5ccc(C(F)(F)F)cc54)c3)cc2)c1>>O=C(O)c1cncc(OCc2ccc(-c3cccc(CN4CCCc5ccc(C(F)(F)F)cc54)c3)cc2)c1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20070021424A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(Br)cc2)CC1>>Brc1ccc(OC2CCNCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110039843A1,Nc1cc(C(F)(F)F)ccc1O.O=C(O)c1ccnc(Cl)c1>>O=C(Nc1cc(C(F)(F)F)ccc1O)c1ccnc(Cl)c1,,c1ccncc1,,CCN=C=NCCCN(C)C,,test
US20150232459A1,CC(C)(C)OC(=O)N1C[C@@H](CO)O[C@@H](C(=O)OCc2ccccc2)C1.CCI.CCOC(C)=O>>CCOC[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H](C(=O)OCC)O1,O=[Ag],CCOC(C)=O,CS(C)=O,,,test
US20120295884A1,CC(C)(C)OC(=O)N1C[C@](O)(C(C)(C)O[SiH2]C(C)(C)C)C[C@H]1C(=O)OCc1ccccc1.CCN(CC)S(F)(F)F>>CC(C)(C)OC(=O)N1C[C@@](F)(C(C)(C)O[SiH2]C(C)(C)C)C[C@H]1C(=O)OCc1ccccc1,,ClCCl,,,,test
US20070093483A1,CCCCCCNC(=S)NN.O=C(O)C(O)c1ccccc1Cl>>OC(c1ccccc1Cl)c1n[nH]c(=S)n1C1CCCCC1,,CN(C)C=O,,,,test
US20100113502A1,CC1CCN(C(=O)c2ccc3[nH]c4c(c3c2)CN(C2CCCC2)CC4)CC1.CCOC(=O)c1ccc(CCl)o1>>COC(=O)c1ccc(Cn2c3c(c4cc(C(=O)N5CCC(C)CC5)ccc42)CN(C2CCCC2)CC3)o1,,CN(C)C=O,,[H-].[Na+],,test
US20080255155A1,Nc1cccc(Oc2ccc([N+](=O)[O-])nc2)c1.O=C(O)C1(C(=O)Nc2ccc(F)cc2)CC1>>NC(=O)C1(C(=O)N(c2ccc(F)cc2)c2cccc(Oc3ccc([N+](=O)[O-])nc3)c2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04381304,CCOC(=O)Cn1cc(C(=O)OCC)c(=O)c2ccccc(=O)c21>>O=C(O)Cn1cc(C(=O)O)c(=O)c2ccccc(=O)c21,,Cl,,,,test
US04515813,C=CCSC(=NCCCCCCCC)NC(C)CCCCC.CCCCCCCCCCCCCCCCCCN=C=O>>C=CCSC(=NCCCCCCCC)N(C(=O)NCCCCCCCCCCCCCCCCCC)C(C)CCCCC,,C1CCOC1,,,,test
US05292785,CC(C)(C)c1cc(C(C)(C)C)c2o[pH]oc3c(C(C)(C)C)c(Cl)c(C(C)(C)C)cc3c2c1.CC(C)(C)c1cc(Cc2cc(C(C)(C)C)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1>>CC(C)(C)c1cc(Cc2cc(C(C)(C)C)cc(C(C)(C)C)c2Op2oc3c(C(C)(C)C)cc(C(C)(C)C)cc3c3cc(C(C)(C)C)cc(C(C)(C)C)c3o2)c(O)c(C(C)(C)C)c1,,Cc1ccccc1,,CC#N,CCN(CC)CC,test
US20070072896A1,Cn1cc(-c2cn(COCC[Si](C)(C)C)c3ncc(B4OC(C)(C)C(C)(C)O4)cc23)cn1.OO>>Cn1cc(-c2cn(COCC[Si](C)(C)C)c3ncc(O)cc23)cn1,,O,,CC(=O)O,,test
US05677336,COc1cc(C=O)c(OC(C)=O)cc1Br>>COc1cc(C=O)c(O)cc1Br,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20110313003A1,C=C(C)Cc1cc(CC)ccc1O>>CCc1ccc2c(c1)CC(C)(C)O2,,ClC(Cl)Cl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20150105370A1,CC(C)(C)OC(=O)N1C[C@@H](F)[C@@H](NCc2ccccc2)C1>>CC(C)(C)OC(=O)N1C[C@H](N)[C@H](F)C1,[Pd],CCO,,,,test
US04147873,C=CC(CCC(=O)O)(NC(=O)OCc1ccccc1)C(=O)O.CCN(CC)CC.CCOC(=O)Cl.COC(=O)[C@H](C)N>>C=CC(N)(CCC(=O)NC(C)C(=O)O)C(=O)NC(C)C(=O)O,,ClCCl,,,,test
US20060235033A1,COc1cc2nccc(Oc3ccc(N)c(Cl)c3)c2cc1OC.C[C@@H](N)c1ccc(F)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)N[C@H](C)c4ccc(F)cc4)c(Cl)c3)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20140094459A1,CC(C)(C)OC(=O)N1CCC[C@@H]1Cn1nc(I)c2c(N)ncnc21.CC1(C)OB(c2ccc(Oc3cccc(F)c3F)cc2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC[C@@H]1Cn1nc(-c2ccc(Oc3cccc(F)c3F)cc2)c2c(N)ncnc21,,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20100125062A1,Cn1c(Nc2ccc(O)cc2)nc2ccccc21.N#Cc1cccnc1F>>Cn1c(Nc2ccc(Oc3ncccc3C#N)cc2)nc2ccccc21,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US06387911B1,CC(C)(C)OC(=O)NCc1ccccc1S(=O)(=O)CC(F)(F)F.Cl>>Cl.NCc1ccccc1S(=O)(=O)CC(F)(F)F,,C1COCCO1,,,,test
US20160002225A1,CN.COc1ccc(Cn2nc(Nc3cccc(/C=C(\C#N)C(=O)O)c3)c3c(Oc4ccc(Oc5ccccc5)cc4)ccnc32)cc1>>CNC(=O)/C(C#N)=C/c1cccc(Nc2nn(Cc3ccc(OC)cc3)c3nccc(Oc4ccc(Oc5ccccc5)cc4)c23)c1,CN(C)C=O,C1CCOC1,ClCCl,O=C(Cl)C(=O)Cl,,test
US04310347,CCCO.CCOC(=O)C(C)Oc1ccc(N(C)c2nnc3cc(Cl)ccc3n2)cc1>>CCCOC(=O)C(C)Oc1ccc(N(C)c2nnc3cc(Cl)ccc3n2)cc1,,O,,O=S(=O)(O)O,,test
US20140031362A1,COc1ccc(C(=O)CC#N)cc1.Cc1cc(N)[nH]n1.O=Cc1ccccc1F>>COc1ccc(C2=C(C#N)C(c3ccccc3F)c3c(C)n[nH]c3N2)cc1,,CC#N,,,,test
US20140179690A1,O=C(NC1=N[C@@]2(c3ccccc3F)CO[C@H](CF)[C@H]2CS1)c1ccccc1>>NC1=N[C@@]2(c3ccccc3F)CO[C@H](CF)[C@H]2CS1,,CO,,C1CCC2=NCCCN2CC1,,test
US06187777B1,CO.Cl.c1cnc(-c2cc3[nH]c(C4CCNCC4)ncc-3n2)cn1>>Cl.O.c1cnc(-c2cc3[nH]c(C4CCNCC4)ncc-3n2)cn1,,CO,,CCOC(C)=O,,test
US20040260088A1,N#Cc1ccc(Cl)cc1F.O=Cc1ccc(O)c2ccccc12>>N#Cc1ccc(Cl)cc1Oc1ccc(C=O)c2ccccc12,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100035942A1,COC(=O)c1cc(C)ccc1O.CS(=O)(=O)Cl>>COC(=O)c1cc(C)ccc1OS(C)(=O)=O,,C1CCOC1,,CCOC(C)=O,[H-].[Na+],test
US20160002218A1,ClCCl.O=C(O)c1nc(C(F)(F)F)cs1>>CC(=O)c1nc(C(F)(F)F)cs1,,CN(C)C=O,,O=S(Cl)Cl,,test
US20100160280A1,O=C1C=C(c2cccnc2Oc2ccc(Nc3ccccn3)cc2)CC1>>OC1C=C(c2cccnc2Oc2ccc(Nc3ccccn3)cc2)CC1,,C1CCOC1,CO,[BH4-].[Na+],,test
US05081145,CCC(=O)CC(C)(C)C(=O)O.NN(Cc1ccc(Cl)cc1)c1ccc(F)cc1>>Cc1c(CC(C)(C)C(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(F)cc12,,CC(C)(C)O,,Cl,,test
US20120202777A1,CC(CCc1ccc(-n2cccn2)cc1)(C(=O)NOC1CCCCO1)S(C)(=O)=O>>CC(CCc1ccc(-n2cccn2)cc1)(C(=O)NO)S(C)(=O)=O,,ClCCl,,CO,Cl,test
US20120165334A1,COc1cccc(Oc2nc3ccccc3[nH]2)c1.Cc1nc(Cl)cc(Cl)n1>>COc1cccc(Oc2nc3ccccc3n2-c2cc(Cl)nc(C)n2)c1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20150336967A1,CC(C)(C)OC(=O)N1CCNCC1.CC(C)n1c(N2CCNCC2)nc2c([N+](=O)[O-])c(Br)c(Br)cc21>>CC(C)(C)OC(=O)N1CCN(c2nc3c([N+](=O)[O-])c(Br)c(Br)cc3[nH]2)CC1,,CCO,,Cl,,test
US20080114022A1,CCBr.N#Cc1ccc([N+](=O)[O-])cc1O>>CCOc1cc([N+](=O)[O-])ccc1C#N,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140221335A1,CI.CS(=O)(=O)c1cc(C#N)ccc1[C@H]1NC(=O)N(c2cccc(C(F)(F)F)c2)C2=C1C(=O)CC2>>CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)[C@H]1c1ccc(C#N)cc1S(C)(=O)=O,,CC#N,CN(C)C=O,CC(C)[N-]C(C)C.[Li+],,test
US20090186886A1,CCN.O=[N+]([O-])c1ccc(CBr)c(CBr)c1>>CCN1Cc2ccc([N+](=O)[O-])cc2C1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20130035329A1,O=[N+]([O-])c1ccc(OCc2nnco2)cc1>>Nc1ccc(OCc2nnco2)cc1,[Fe],CO,,Cl,,test
US20080085890A1,COC(OC)OC.O=C1Cc2cc(C3CCCC3)ccc2C(=O)N1>>COC=C1C(=O)NC(=O)c2ccc(C3CCCC3)cc21,,CC(=O)O,,,,test
US04065473,Cc1cc2c(cc1C)CC(C)NC(=O)C2.Cl>>Cc1cc2c(cc1C)CC(C)NCC2.Cl,,C1CCOC1,,B,,test
US20130345212A1,COC(=O)c1cc(-c2ccc(N(C)C)cc2)c(Cl)cc1N.Cc1cc(CC(=O)O)on1>>COC(=O)c1cc(-c2ccc(N(C)C)cc2)c(Cl)cc1NC(=O)Cc1cc(C)no1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150104384A1,COC(CBr)OC.NC1CCC(Cl)NN1>>Clc1ccc2nccn2n1,,CCO,,Br,,test
US20080261952A1,Nc1cccc(-c2cccc(N3CCCC3)n2)c1.O=C=Nc1ccc(Cl)cc1>>O=C(Nc1ccc(Cl)cc1)Nc1cccc(-c2cccc(N3CCCC3)n2)c1,,ClCCl,,,,test
US20140296206A1,CC(C)(C)OC(=O)N1C[C@@H]2CC[C@H](C1)N2c1ncc(Cc2ccccc2)cn1>>c1ccc(Cc2cnc(N3[C@H]4CC[C@@H]3CNC4)nc2)cc1,,C1COCCO1,Cl,,,test
US20080214549A1,CC(C)c1nn(Cc2ccc(Br)cc2)c(=O)c(C(=O)NCC(=O)O)c1O.O=[N+]([O-])c1ccc(B(O)O)cc1>>CC(C)c1nn(Cc2ccc(-c3ccc([N+](=O)[O-])cc3)cc2)c(=O)c(C(=O)NCC(=O)O)c1O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20100022515A1,CC(C)OC(=O)N1CCC(CCCO)CC1.CS(=O)(=O)Cl>>CC(C)OC(=O)N1CCC(CCCOS(C)(=O)=O)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20050250836A1,CCOCCOCCn1c(C=O)cc2c1CC(c1ccccc1Cl)C1C(=O)NC(=O)C21>>CCOCCOCCn1c(C=O)cc2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O,O=[Mn]=O,,,,,test
US20080167307A1,CCCCCCCNCCc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1.O=C(O)c1ccccc1-c1ccccc1>>CCCCCCCN(CCc1csc(SC(C)(C)C(=O)O)n1)C(=O)c1ccccc1-c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150148333A1,CCOC(=O)Cc1onc(C)c1-c1ccc(Cl)cc1N>>Cc1noc2c1-c1ccc(Cl)cc1NC(=O)C2,,CCO,,Cl,,test
US04139545,Cc1cc(C)c(C(=O)CCCCC(=O)O)c(O)c1C>>Cc1cc(C)c(CCCCCC(=O)O)c(O)c1C,[Zn],O,,Cc1ccccc1,Cl,test
US20070249680A1,CC1(C)OB(C2=CCCCC2)OC1(C)C.COC(=O)C1(c2ccc(N)c(Br)c2)CCOCC1>>COC(=O)C1(c2ccc(N)c(C3=CCCCC3)c2)CCOCC1,,CCOC(C)=O,ClCCl,,,test
US20030153570A1,O=C(Cl)C(=O)Cl.O=C(O)c1cc([N+](=O)[O-])ccc1Cl>>O=C(Cl)c1cc([N+](=O)[O-])ccc1Cl,CN(C)C=O,ClCCl,,,,test
US20110136735A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](C(=O)O)CC1.C[C@@H](N)c1ccc(F)cc1>>C[C@@H](NC(=O)[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1)c1ccc(F)cc1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110178001A1,CCOP(=O)(CP(=O)(OCC)c1ccc(OC(=O)CC)c(C(C)(C)CC(=O)N(Cc2ccccc2)[C@@H](Cc2ccccc2)C(=O)O)c1)OCC>>CCOP(=O)(CP(=O)(OCC)c1ccc(OC(=O)CC)c(C(C)(C)CC(=O)N[C@@H](Cc2ccccc2)C(=O)O)c1)OCC,[Pd],CO,,,,test
US20060264460A1,CC(C)c1nc[nH]c1C=O.N#Cc1cnc2c(Br)cc(NCc3ccccn3)cc2c1Nc1ccc(F)c(Cl)c1>>CC(C)c1nc[nH]c1CNc1cc(Br)c2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1,,C1CCOC1,CO,[BH3-]C#N.[Na+],,test
US04454340,COc1cccc(O)c1.O=C(Cl)Oc1ccccc1>>COc1ccc(C(=O)Oc2ccccc2)c(O)c1,,ClCCl,O,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US06211242B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)CCNCCOc1ccccc1N(C)C(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C)cc2)cc1>>COC(=O)CCN(CCOc1ccccc1N(C)C(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C)cc2)cc1)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20090099184A1,CO.O=C(NCc1ccc(Cl)cc1Cl)c1ccc(F)nc1>>COc1ccc(C(=O)NCc2ccc(Cl)cc2Cl)cn1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20070003539A1,NCc1ccccc1S(=O)(=O)C1CCC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NCc1ccccc1S(=O)(=O)C1CCC1)C(F)(F)F,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20060014958A1,CC(C)(C)OC(=O)N1CCC(N)CC1.S=C(n1ccnc1)n1ccnc1>>CC(C)(C)OC(=O)N1CCC(N=C=S)CC1,,CN(C)C=O,,,,test
US20060089365A1,CNCC(C)C.O=C(O)c1cccc(-c2cc(-c3ccc(Cl)nc3)on2)c1>>CC(C)CN(C)c1ccc(-c2cc(-c3cccc(C(=O)O)c3)no2)cn1,,C1CCOC1,,CCN(CC)CC,,test
US03936419,COC(=O)c1ccc(C(=O)C(C)Br)cc1.COC(=O)c1ccc(C(N)=O)cc1>>COC(=O)c1ccc(-c2nc(C)c(-c3ccc(C(=O)OC)cc3)o2)cc1,,Cc1ccccc1,,O=P(Cl)(Cl)Cl,,test
US20080096877A1,CC(C)(C)OC(=O)O.COC(OC)C(CN)SCc1ccccc1>>COC(OC)C(CNC(=O)OC(C)(C)C)SCc1ccccc1,,C1CCOC1,,[Na+].[OH-],,test
US20140206694A1,CCC(Nc1cccc(Cl)c1[N+](=O)[O-])C(=O)O>>CCC1Nc2cccc(Cl)c2NC1=O,,CCO,,Cl,[K+].[OH-],test
US20110245353A1,CCOC(=O)c1c(C)nc2cccc(OCC(C)C)c2c1N>>Cc1nc2cccc(OCC(C)C)c2c(N)c1C(=O)O,,CCO,,[Na+].[OH-],,test
US20120088748A1,CC(C)(C)OC(=O)N1CCOC(CO[Si](C)(C)C(C)(C)C)(c2ccc(Cl)c(Cl)c2)C(=O)C1>>CC(C)(C)OC(=O)N1CCOC(CO[Si](C)(C)C(C)(C)C)(c2ccc(Cl)c(Cl)c2)C(O)C1,,CO,,[BH4-].[Na+],[Cl-].[NH4+],test
US20030036558A1,NCc1cccc([N+](=O)[O-])c1.O=C(Cl)c1ccc(F)cc1O>>O=C(NCc1cccc([N+](=O)[O-])c1)c1ccc(F)cc1O,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20080280950A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(OC(F)(F)C(F)(F)F)cc2)CC1.Cl>>Cl.FC(F)(F)C(F)(F)Oc1ccc(OC2CCNCC2)cc1,,C1COCCO1,,,,test
US20120083514A1,CS(=O)(=O)OCCCCCCCCCSCCCC(F)(F)C(F)(F)F.O=C1NC2(CCC2)C(=O)N1c1ccc([N+](=O)[O-])c(C(F)(F)F)c1>>O=C1N(c2ccc([N+](=O)[O-])c(C(F)(F)F)c2)C(=O)C2(CCC2)N1CCCCCCCCCSCCCC(F)(F)C(F)(F)F,,CN(C)C=O,,O,[H-].[Na+],test
US20100331296A1,CC1(C)OB(c2cccc(NC(=O)NCC(F)(F)F)c2)OC1(C)C.COC(=O)c1ccn2c(I)cnc2c1>>O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(C(=O)O)ccn23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150225375A1,N[C@@H]1C[C@H]1c1ccccc1.Nc1ccnc(N2CCC(=O)CC2)n1>>Nc1ccnc(N2CCC(N[C@@H]3C[C@H]3c3ccccc3)CC2)n1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04713457,Cc1ccc(S(=O)(=O)OC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)cc1.c1nc[nH]n1>>CN1C[C@H](Cn2cncn2)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21,,O,,CN(C)C=O,[H-].[Na+],test
US20110081315A1,CCI.O=C(O)c1cc([N+](=O)[O-])ccc1F>>CCOC(=O)c1cc([N+](=O)[O-])ccc1F,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US05260331,CCCC(C)NC(=O)c1ccc(Cl)cc1>>CCCC(C)NCc1ccc(Cl)cc1,,C1CCOC1,,,,test
US20150361067A1,Cc1ccc(Cl)cc1CCl.[C-]#N>>Cc1ccc(Cl)cc1CC#N,,CS(C)=O,,O,,test
US20040192653A1,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.CC(C)(O)Cn1ncc2cc(Oc3ccc(F)cc3C#N)ccc21>>CC(C)(Cn1ncc2cc(Oc3ccc(F)cc3C#N)ccc21)O[Si](C)(C)C(C)(C)C,,CCOCC,ClCCl,Cc1cccc(C)n1,,test
US20040077646A1,C=CCOC(=O)Nc1ccc(/C=C(/N=[N+]=[N-])C(=O)OCC)cc1>>C=CCOC(=O)Nc1ccc2cc(C(=O)OCC)[nH]c2c1,,Cc1ccccc1,,,,test
US04322442,C#CC(O)(c1ccccc1)c1ccncc1.II>>OC(C#CI)(c1ccccc1)c1ccncc1,,CO,O,[Na+].[OH-],,test
US20060079567A1,O=C(Cl)C1CN(Cc2ccccc2)CC1c1cc(Br)c(Br)s1>>O=C1c2c(sc(Br)c2Br)C2CN(Cc3ccccc3)CC12,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US04663453,NC(=O)c1ccccc1N1CCc2cc(Cl)cc([N+](=O)[O-])c21>>NC(=O)c1ccccc1N1CCc2cc(Cl)cc(N)c21,,CCO,CN(C)C=O,,,test
US20150105403A1,NC(=O)c1ccc(Br)c(C(N)=O)c1>>N#Cc1ccc(Br)c(C#N)c1,CN(C)C=O,,,O=P(Cl)(Cl)Cl,,test
US20060094588A1,NCc1ccccc1C(F)(F)F.O=Cc1nc2ccccc2[nH]1>>FC(F)(F)c1ccccc1C/N=C/c1nc2ccccc2[nH]1,CC(=O)O,CO,,,,test
US20070197526A1,COc1ccc(-c2c(C)nn(-c3ccc(OCc4ccccc4)cc3)c2C)cc1>>COc1ccc(-c2c(C)nn(-c3ccc(O)cc3)c2C)cc1,[Pd],C1CCOC1,CO,,,test
US06096741,CNC.CON=C(C)C(=NOCc1ccccc1)C(=O)O>>CON=C(C)C(=NOCc1ccccc1)C(=O)N(C)C,CN(C)C=O,Cc1ccccc1,,O,O=S(Cl)Cl,test
US05696256,CC(=O)Cl.CSC(=N[N+](=O)[O-])NCc1ccc(Cl)nc1>>CSC(=N[N+](=O)[O-])N(Cc1ccc(Cl)nc1)C(C)=O,,c1ccncc1,,CC#N,,test
US20110015178A1,FC(F)(F)CN1CCNC2CCCCC21.O=C(O)c1csc(-c2cn[nH]c2)c1>>O=C(c1csc(-c2cn[nH]c2)c1)N1CCN(CC(F)(F)F)C2CCCCC21,,CC#N,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060235031A1,C1CNC1.Cc1ccc(S(=O)(=O)OC[C@@H]2C[C@@H](n3cc(-c4ccc5ccc(-c6ccccc6)nc5c4)c4c(N)ncnc43)C2)cc1>>Nc1ncnc2c1c(-c1ccc3ccc(-c4ccccc4)nc3c1)cn2[C@@H]1C[C@@H](CN2CCC2)C1,,C1CCOC1,,,,test
US20110160198A1,COC(=O)[C@H](Cc1ccc(-c2ccnc(C)c2C)cc1)NC(=O)[C@@H]1Cc2cc3c(cc2CN1C(=O)OC(C)(C)C)O[C@@H](c1ccc(O)cc1)CO3.C[C@@H](N=C=O)c1ccccc1.Clc1cccc(Cl)c1CBr>>Cc1nccc(-c2ccc(C[C@H](NC(=O)[C@@H]3Cc4cc5c(cc4CN3C(=O)N[C@H](C)c3ccccc3)O[C@@H](c3ccc(OCc4c(Cl)cccc4Cl)cc3)CO5)C(=O)O)cc2)c1C,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20040082607A1,CC(C)Cn1c(CNC(=O)OC(C)(C)C)c(-c2ccccc2)c2cc(-c3nn[nH]n3)ccc2c1=O.Cl>>CC(C)Cn1c(CN)c(-c2ccccc2)c2cc(-c3nn[nH]n3)ccc2c1=O.Cl,,C1CCOC1,CCOC(C)=O,,,test
US06117987,CCOC(=O)CC1(O)CCC(C)(C)c2cc(C3(C)OCCO3)ccc21.c1ccccc1>>CCOC(=O)CCC1=CCC(C)(C)c2cc(C(C)=O)ccc21,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US06043241,COc1ccc(C2=C(Cc3ccc4c(c3)OCO4)C(O)(c3cc(OC)c(OC)c(OC)c3)OC2=O)cc1>>COc1ccc(/C(C(=O)O)=C(/Cc2ccc3c(c2)OCO3)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1,,O,,CO,,test
US05527882,CC(C)(C)OC(=O)N=[N+]=[N-].O=C(O)CNCc1ccccc1>>CC(C)(C)OC(=O)N(CC(=O)O)Cc1ccccc1,,C1COCCO1,O,Cl,O=C([O-])O.[Na+],test
US20140235591A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCCCCC[C@@H]1CCc2cc([C@H]3CC[C@](N)(CO)C3)ccc2C1>>CCCCCC[C@@H]1CCc2cc([C@H]3CC[C@@](CO)(NC(=O)OC(C)(C)C)C3)ccc2C1,,ClCCl,,,,test
US20060194837A1,COC(=O)Cl.COC(=O)NCC(c1ccc(Br)cc1)c1cccnc1.ClCCl.NCC(c1ccc(Br)cc1)c1cccnc1>>C(#Cc1ccc2c(c1)CNCC2c1cccnc1)CCN1CCCCC1,,ClCCl,O,,,test
US20140206663A1,Cc1cc2c(cc1NC1CN(C(=O)OC(C)(C)C)C1)N1C(=NNC(=O)[C@@H]1C)CO2.O=C(O)C(F)(F)F>>Cc1cc2c(cc1NC1CNC1)N1C(=NNC(=O)[C@@H]1C)CO2.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20050171087A1,O=CN[C@@H]1CCCN2c3cc(Cl)ccc3Oc3ccccc3[C@H]12.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>S=CN[C@@H]1CCCN2c3cc(Cl)ccc3Oc3ccccc3[C@H]12,,C1COCCO1,,,,test
US20030096826A1,CC(=O)Cl.CON(C)C(=O)C(CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccc(N)cc1OCc1ccccc1>>CON(C)C(=O)C(CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccc(NC(C)=O)cc1OCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20110105461A1,C1CNC1.Cc1ccc(S(=O)(=O)OC[C@H]2COc3c(Cl)cc(S(C)(=O)=O)cc3O2)cc1>>CS(=O)(=O)c1cc(Cl)c2c(c1)O[C@@H](CN1CCC1)CO2,,CC#N,,,,test
US20040048858A1,CC(C)CN=C=S.COc1ccc(C(=O)NN)c(OC)c1>>COc1ccc(C(=O)NNC(=S)NCC(C)C)c(OC)c1,,CCO,,,,test
US20120170098A1,Br[Mg]c1ccccc1.O=C(Cl)C(=O)Cl.c1ccccc1>>O=C(c1ccccc1)c1ccccc1,,Cc1ccccc1,ClCCl,CN(C)C=O,,test
US20110281845A1,O=C(CI)NCCc1ccccc1.O=C(Nc1ccc(-c2ccccc2Cl)[nH]c1=O)OCc1ccccc1>>O=C(Cn1c(-c2ccccc2Cl)ccc(NC(=O)OCc2ccccc2)c1=O)NCCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20120214807A1,COc1ccc(N2CCC(N3CC[C@@H](NC(=O)CN)C3)CC2)cc1.O=C(Cl)c1ccc(Cl)c(Cl)c1>>NC(=O)c1ccccc1,,ClCCl,ClCCl,CCN(CC)CC,O=C([O-])O.[Na+],test
US05962509,CCCN(CCC)C(=O)C(CCC(=O)O)NC(=O)C(C(=O)O)=C1SC=CS1>>CCCN(CCC)C(=O)C(CCC(=O)O)NC(=O)C=C1SC=CS1,,C1COCCO1,,,,test
US20070010670A1,O=C(Cl)c1cc(Cl)c(OCc2ccccc2)c(Cl)c1.c1cnc2c(c1)OCCN2>>O=C(c1cc(Cl)c(OCc2ccccc2)c(Cl)c1)N1CCOc2cccnc21,,ClC(Cl)Cl,,CCN(CC)CC,,test
US05248689,CCCCc1ncc(C=O)n1Cc1ccccc1Cl.COC(=O)[C@@H](N)Cc1cccs1>>CCCCc1ncc(C=N[C@@H](Cc2cccs2)C(=O)OC)n1Cc1ccccc1Cl,,O,,Cc1ccccc1,,test
US20100063091A1,COCCCc1cc(CNC2CC2)cc(O[Si](C)(C)C(C)(C)C)c1.Cc1cc(Cl)c(OCCOc2ccc([C@H]3CCN(C(=O)OC(C)(C)C)C[C@@H]3C(=O)O)cc2)c(Cl)c1>>COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)cc(O[Si](C)(C)C(C)(C)C)c1,,CCOCC,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04299840,CCCCCCCCCCBr.O=C1CCCN1>>CCCCCCCCCCN1CCCC1=O,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20160222028A1,CC(C)[C@@H](N)CO.COC(=O)c1ccc(CBr)c(Br)c1>>COC(=O)c1ccc(CN[C@@H](CO)C(C)C)c(Br)c1,,CC#N,,,,test
US20120302540A1,CN1C[C@@H](c2ccccc2)[C@@]2(CCCN(C(=O)[C@@H](CCOc3ccccc3)NC(=O)C(C)(C)NC(=O)OC(C)(C)C)C2)C1=O>>CN1C[C@@H](c2ccccc2)[C@@]2(CCCN(C(=O)[C@@H](CCOc3ccccc3)NC(=O)C(C)(C)N)C2)C1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120077781A1,CCOC(=O)C(C)(C)CCCCCBr.Cc1cc(N)c([N+](=O)[O-])cc1C>>CCOC(=O)C(C)(C)CCCCCNc1cc(C)c(C)cc1[N+](=O)[O-],,ClCCl,,,,test
US20120277244A1,CC(C)(C)OC(=O)NC1=NC(c2cc([N+](=O)[O-])ccc2F)(C(F)F)CN(C(=O)OCC(Cl)(Cl)Cl)C1>>CC(C)(C)OC(=O)NC1=NC(c2cc(N)ccc2F)(C(F)F)CN(C(=O)OCC(Cl)(Cl)Cl)C1,[Fe],CO,,[Cl-].[NH4+],,test
US20090075971A1,C=CCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)COc2ccccc21>>CCCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)COc2ccccc21,[Pd],CO,,,,test
US05070089,CI.S=C=S.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>CSC(=S)N1CCN(C(c2ccccc2)c2ccccc2)CC1,,CO,,,,test
US20030232818A1,CCOC(=O)c1cn(C(C)(C)C)c2nc(N3CCCC3)c(Br)cc2c1=O>>O=C(O)c1c[nH]c2nc(N3CCCC3)c(Br)cc2c1=O,,O,,CCO,Cl,test
US20100069351A1,CI.Cc1noc(-c2ccc(N3CCC4(C3)C(=O)Nc3ccccc34)nn2)n1>>Cc1noc(-c2ccc(N3CCC4(C3)C(=O)N(C)c3ccccc34)nn2)n1,,CN(C)C=O,,[H-].[Na+],,test
US08084607B2,BrP(Br)Br.CN(C)C=O.O=C1CCOCC1>>O=CC1=C(Br)CCOC1,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20120172599A1,CCCCN(CCCC)c1cccc(OC)c1.N#CC(C#N)=c1ccc(=C(C#N)C#N)cc1>>CCCCN(CCCC)c1ccc(C(C#N)=c2ccc(=C(C#N)C#N)cc2)c(OC)c1,,CN(C)C=O,,,,test
US20070232628A1,CC(C)c1ccc(N)cc1.CCC(C(=O)O)C1(C)OCCO1>>CC(C)c1ccc(C(C(N)=O)C2(C)OCCO2)cc1,,ClCCl,,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20150291593A1,CSc1n[nH]c(N)c1C(N)=O.NC=O>>CSc1n[nH]c2ncnc(O)c12,,O,,,,test
US20070254866A1,COC(=O)c1cn(C2CC2)c2c(OC)c(F)c(F)c(N(C)C(=O)C(F)(F)F)c2c1=O>>CNc1c(F)c(F)c(OC)c2c1c(=O)c(C(=O)O)cn2C1CC1,,CC(=O)O,Cl,,,test
US05374606,CCOC=C(C(=O)c1ccc(Cl)c(CSC)c1SC)C(=O)C1CC1.NO>>CSCc1c(Cl)ccc(C(=O)c2cnoc2C2CC2)c1SC,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20080234262A1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(N4CCOCC4)nc(-c4ccc([N+](=O)[O-])cc4)nc32)CC1>>CCOC(=O)N1CCC(n2ncc3c(N4CCOCC4)nc(-c4ccc([N+](=O)[O-])cc4)nc32)CC1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US04330550,CCOC(=O)CCCCCCCNC(=O)n1cc(-c2ccccc2)oc1=O>>O=C(O)CCCCCCCn1c(-c2ccccc2)c[nH]c1=O,,CC(=O)O,,Br,,test
US20060154931A1,Cc1nc(-c2ccc(O)cc2)c(-c2ccncc2)o1.ClCc1ccc2ccccc2n1>>Cc1nc(-c2ccc(OCc3ccc4ccccc4n3)cc2)c(-c2ccncc2)o1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030139418A1,COC(=O)c1ccc(CCc2cccnc2CC(Cl)c2ccccc2)cc1>>COC(=O)c1ccc(CCc2cccnc2CCc2ccccc2)cc1,[Pd],CCO,,,,test
US20150111894A1,CCc1cc(Br)ccc1OCC1(C#N)CC1.O=c1[nH]ccc2oc(-c3ccc(Cl)cc3)cc12>>CCc1cc(-n2ccc3oc(-c4ccc(Cl)cc4)cc3c2=O)ccc1OCC1(C#N)CC1,[Cu]I,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=C([O-])[O-].[K+].[K+],test
US06495576B2,Cc1ccc(S(=O)(=O)O)cc1.Cc1ccccc1.NC(=O)c1ccncc1.c1ccc2[nH]nnc2c1>>CC(C)(Cc1ccccc1)C(NC(=O)c1ccncc1)n1nnc2ccccc21,,Cc1ccccc1,,,,test
US04845284,O=[N+]([O-])c1cccc(S(=O)(=O)Cl)c1.OCCNCCO>>O=[N+]([O-])c1cccc(S(=O)(=O)N(CCO)CCO)c1,,C1CCOC1,,,,test
US20140213580A1,CC(C)C(=O)C(=CN(C)C)c1ccccc1.N#CCC(N)=O>>CC(C)c1nc(O)c(C#N)cc1-c1ccccc1,,CN(C)C=O,,CO,[H-].[Na+],test
US20120329877A1,CC(C)CO.CC(C)[Si](OCCc1cccc(CC2=C(O)CCC2=O)c1)(C(C)C)C(C)C>>CC(C)COC1=C(Cc2cccc(CCO)c2)C(=O)CC1,,c1ccccc1,,,,test
US20150175617A1,COC(=O)c1cccc2[nH]c3c(c12)C(=O)CNC3.O=C(Cl)C1CC1>>COC(=O)c1cccc2[nH]c3c(c12)C(=O)CN(C(=O)C1CC1)C3,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05753595,CCOC(=O)N(Cl)Cl.Cn1c(C(F)(F)F)cc(=O)n(-c2ccc(Cl)c3nc(C(C)(C)C)oc23)c1=O>>Cn1c(C(F)(F)F)c(Cl)c(=O)n(-c2ccc(Cl)c3nc(C(C)(C)C)oc23)c1=O,Cl,CC(=O)O,,O,O=C([O-])[O-].[Na+].[Na+],test
US04017529,CCI.CN(C)C(=O)NC(N)=S>>CCSC(=N)NC(=O)N(C)C,,CO,,O,[Na+].[OH-],test
US04590201,Cc1ccc(C(=O)c2c(Cl)cccc2Cl)cc1.O=C1CCC(=O)N1Br>>O=C(c1ccc(CBr)cc1)c1c(Cl)cccc1Cl,O=C(OOC(=O)c1ccccc1)c1ccccc1,c1ccccc1,,,,test
US20140206663A1,CC1C(=O)NN=C2COc3cc(Br)c(C4CCN(C(=O)OC(C)(C)C)CC4)cc3N21.OB(O)C1CC1>>CC1C(=O)NN=C2COc3cc(C4CC4)c(C4CCN(C(=O)OC(C)(C)C)CC4)cc3N21,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US05726306,CCOC(=O)CNC(=O)C[C@H]1O[C@@H](c2ccccc2)c2cc(Cl)ccc2N(C(C)C)C1=O>>CC(C)N1C(=O)[C@@H](CC(=O)NCC(=O)O)O[C@@H](c2ccccc2)c2cc(Cl)ccc21,,CO,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20100075953A1,CC(C)(C)OC(=O)N1CCN(c2ccc(OCCCN3CCCCC3)cc2)CC1>>c1cc(N2CCNCC2)ccc1OCCCN1CCCCC1,,O=C(O)C(F)(F)F,,,,test
US05278158,CC(=O)Nc1cc2c(cc1[N+](=O)[O-])N(c1cccc[n+]1[O-])CC(C)(C)O2>>CC1(C)CN(c2cccc[n+]2[O-])c2cc([N+](=O)[O-])c(N)cc2O1,,CCO,,Cl,O=C([O-])O.[Na+],test
US20100216814A1,Cc1ccc2c(c1)c1c(n2C2CCCCC2OS(C)(=O)=O)CCN(C)C1>>Cc1ccc2c(c1)c1c(n2C2=CCCCC2)CCN(C)C1,,CN1CCCC1=O,O,[K+].[OH-],,test
US20040157873A1,CCOC(=O)c1cc2cc([N+](=O)[O-])ccc2n1C(=O)c1ccccc1>>CCOC(=O)c1cc2cc(N)ccc2n1C(=O)c1ccccc1,[Pd],C1CCOC1,,,,test
US20060004002A1,COC(=O)c1scc(C)c1N.O=CO>>COC(=O)c1scc(C)c1NC=O,,O=CO,,CC(=O)OC(C)=O,,test
US20100076041A1,CCOC(=O)CCn1ccc2c(C(=O)N3CC4(C)CC3CC(C)(C)C4)cccc21>>CC1(C)CC2CC(C)(CN2C(=O)c2cccc3c2ccn3CCC(=O)O)C1,,CCO,,Cl,[Na+].[OH-],test
US20140296245A1,COc1ccc(CN(c2ncns2)S(=O)(=O)c2cc(F)c(F)cc2F)c(OC)c1.OC[C@@H]1CCCC[C@H]1c1ccc(F)cc1>>O=S(=O)(Nc1ncns1)c1cc(F)c(OC[C@@H]2CCCC[C@H]2c2ccc(F)cc2)cc1F,,C1CCOC1,CCOC(C)=O,[Cl-].[NH4+],C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20100029650A1,CC(C)(C)OC(=O)NCCN.O=S(=O)(Cl)c1ccc(Br)cc1>>CC(C)(C)OC(=O)NCCNS(=O)(=O)c1ccc(Br)cc1,,ClCCl,,CCN(CC)CC,,test
US20120053173A1,CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2sc3ccccc3c2C)C2CCCCC2)cn1>>Cc1c(C(Nc2ccc(C(=O)N(C)CCC(=O)O)nc2)C2CCCCC2)sc2ccccc12,,CCO,,C1CCOC1,[Na+].[OH-],test
US20150183759A1,CCCC[C@H]1[C@H](C)OC(=O)[C@@H](NC(=O)c2nccc(OC)c2O)CCC[C@@H]1OC(=O)C(C)C.CCOCC(=O)OCCl>>CCCC[C@H]1[C@H](C)OC(=O)[C@@H](NC(=O)c2nccc(OC)c2OCOC(=O)COCC)CCC[C@@H]1OC(=O)C(C)C,,CC(C)=O,,[I-].[Na+],,test
US20100130495A1,C=O.Cc1nccn1-c1ccc(Nc2nc(O)c3c(n2)CCNC3)cc1>>Cc1nccn1-c1ccc(Nc2nc(O)c3c(n2)CCN(C)C3)cc1,,CO,O,CC(=O)O,[BH3-]C#N.[Na+],test
US20010054207A1,COCCl.O=[N+]([O-])c1ccc(O)c(Br)c1>>COCOc1ccc([N+](=O)[O-])cc1Br,,C1CCOC1,,[H-].[Na+],,test
US05500453,CCCC[B-](c1ccccc1)(c1ccccc1)c1ccccc1.C[S+](C)Cc1ccc(Cl)cc1>>CCCC[B-](c1ccccc1)(c1ccccc1)c1ccccc1.C[S+](C)Cc1ccc(Cl)cc1,,O,,[Cl-].[Li+],,test
US05616586,O=C(O)CC1CCc2cc(Br)cc3[nH]c(=O)c(=O)n1c23.ONc1ccccc1>>O=C(CC1CCc2cc(Br)cc3[nH]c(=O)c(=O)n1c23)N(O)c1ccccc1,,CC(=O)O,CCOC(C)=O,,,test
US20130252944A1,CCC(O)c1nn(Cc2ccc(OC)cc2)cc1-c1nc(NC(=O)OC(C)(C)C)sc1C=O>>CCC(=O)c1nn(Cc2ccc(OC)cc2)cc1-c1nc(NC(=O)OC(C)(C)C)sc1C=O,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US05852011,CC(=O)Nc1cccc([N+](=O)[O-])c1>>CCNc1cccc([N+](=O)[O-])c1,,C1CCOC1,,Cl,,test
US20090118283A1,COC(=O)c1ccc(C(CNC(=O)C2(c3ccc(Cl)cc3)CC2)NC(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)NC(CNC(=O)C1(c2ccc(Cl)cc2)CC1)c1ccc(C(=O)O)cc1,,CO,,[Na+].[OH-],,test
US20140256736A1,COc1ccc(CN(c2ncns2)S(=O)(=O)c2cc(F)c(Oc3ccc(Cl)cc3-c3ncc4cnccn34)cc2F)c(OC)c1>>O=S(=O)(Nc1ncns1)c1cc(F)c(Oc2ccc(Cl)cc2-c2ncc3cnccn23)cc1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080161294A1,CS(=O)(=O)Cl.C[C@H](CO)N(Cc1ccccc1NC(=O)c1ccc(N2CCCC2)cc1Cl)C(=O)OC(C)(C)C>>C[C@H](COS(C)(=O)=O)N(Cc1ccccc1NC(=O)c1ccc(N2CCCC2)cc1Cl)C(=O)OC(C)(C)C,,C1CCOC1,,CCN(CC)CC,O,test
US08372840B2,CC(C)(C)OC(=O)CBr.Cn1ccc(S(=O)(=O)N(Cc2ccc(Cl)cc2)c2cccc(O)c2)n1>>Cn1ccc(S(=O)(=O)N(Cc2ccc(Cl)cc2)c2cccc(OCC(=O)OC(C)(C)C)c2)n1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040209892A1,CC(C)N1CCNCC1.O=[N+]([O-])c1ccc(Br)c(OC(F)F)c1>>CC(C)N1CCN(c2ccc([N+](=O)[O-])cc2OC(F)F)CC1,,CS(C)=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20060178374A1,CC(Oc1cc(-c2ccc(C(=O)N3CCN(C(=O)OC(C)(C)C)CC3)cc2)cnc1N)c1c(Cl)ccc(F)c1Cl.CCO>>CCOc1ccc(Cl)c(C(C)Oc2cc(-c3ccc(C(=O)N4CCN(C(=O)OC(C)(C)C)CC4)cc3)cnc2N)c1Cl,,O,,CS(C)=O,[H-].[Na+],test
US20050267105A1,CC1(C)OCCn2c1nc(C(=O)O)c(OCc1ccccc1)c2=O.NCc1ccc(F)cc1O>>CC1(C)OCCn2c1nc(C(=O)NCc1ccc(F)cc1O)c(OCc1ccccc1)c2=O,CN(C)c1ccncc1,CN(C)C=O,,Cl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05482943,CC(C)(C)[Si](C)(C)Cl.Nc1ncccc1CO>>CC(C)(C)[Si](C)(C)OCc1cccnc1N,,O,,CN(C)C=O,c1c[nH]cn1,test
US20130116234A1,COC(=O)c1c(C(C)C)nc2ccc(Cl)cc2c1Br.OB(O)c1cccc(OC(F)(F)F)c1>>COC(=O)c1c(C(C)C)nc2ccc(Cl)cc2c1-c1cccc(OC(F)(F)F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US08236963B2,CC(C)(O)C#N.COC(=O)CN1C(=O)/C(=C(/C#N)C(=O)OC)c2cc(Cl)ccc21>>COC(=O)CN1C(=O)C(C#N)(C(C#N)C(=O)OC)c2cc(Cl)ccc21,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20090270402A1,Cc1ccc(S(=O)(=O)C(NC=O)c2ccc(F)cc2F)cc1>>[C-]#[N+]C(c1ccc(F)cc1F)S(=O)(=O)c1ccc(C)cc1,,COCCOC,,O=P(Cl)(Cl)Cl,,test
US20140213581A1,COC1NC(=O)c2ncc(Cl)cc2C1F.O=P(Cl)(Cl)Cl>>Fc1cnc(Cl)c2ncc(Cl)cc12,,CC#N,,,,test
US20120046290A1,CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3cccc(C(=O)O)c3)cc2)no1.OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3cccc(NC(=O)OCc4ccccc4)c3)cc2)no1,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US20130017194A1,COC(=O)Cc1ccccc1C#C[Si](C)(C)C>>C#Cc1ccccc1CC(=O)OC,,ClCCl,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04167567,Clc1cnccn1.O=C(c1ccc(Nc2ccnc3cc(C(F)(F)F)ccc23)cc1)N1CCNCC1>>O=C(c1ccc(Nc2ccnc3cc(C(F)(F)F)ccc23)cc1)N1CCN(c2cnccn2)CC1,,OCCO,,CCN(CC)CC,,test
US20070197518A1,C[C@@H]1CNC[C@@H](C)O1.O=Cc1cc(Br)c(F)c(F)c1F>>CC1CN(c2c(C=O)cc(Br)c(F)c2F)CC(C)O1,,CC#N,,CCN(CC)CC,Cl,test
US20100029753A1,COCN(c1ccsc1C(=O)OC)S(=O)(=O)c1ccc(C(C)(C)C)cc1C=Cc1ccccc1>>COC(=O)c1sccc1NS(=O)(=O)c1ccc(C(C)(C)C)cc1C=Cc1ccccc1,,C1CCOC1,,Cl,,test
US04226775,CC(O)=S.O=C(C=CC(=O)N1CCC[C@H]1C(=O)O)c1ccccc1>>CC(=O)SC(CC(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)O,,ClC(Cl)(Cl)Cl,,,,test
US20110112076A1,CC(C)CCN([C@@H](C(=O)OC(C)(C)C)C(C)C)S(=O)(=O)c1ccc2cc(O)ccc2c1>>CC(C)CCN([C@@H](C(=O)O)C(C)C)S(=O)(=O)c1ccc2cc(O)ccc2c1,,CCOC(C)=O,Cl,,,test
US20100004331A1,CCOC(=O)Cc1ccc(OC)c(Oc2ccc(Cl)cc2C=O)c1>>CCOC(=O)Cc1ccc(OC)c(Oc2ccc(Cl)cc2CO)c1,,CO,,[BH4-].[Na+],,test
US20100087429A1,CC(C)(C)CI.NC1=N[C@@]2(CO1)c1cc(Br)ccc1Oc1ncc(O)cc12>>CC(C)(C)COc1cnc2c(c1)[C@]1(COC(N)=N1)c1cc(Br)ccc1O2,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20120165331A1,Cc1ccc(S(=O)(=O)n2cc(CN3CCC4(CCN(C(=O)OC(C)(C)C)C4)C3=O)c3ccccc32)cc1.Cl>>Cc1ccc(S(=O)(=O)n2cc(CN3CCC4(CCNC4)C3=O)c3ccccc32)cc1.Cl,,ClCCl,,C1COCCO1,,test
US20060019940A1,CC1Cc2cc(CNC(=O)OC(C)(C)C)ccc2N(c2ccccc2)CCO1>>CC1Cc2cc(CN)ccc2N(c2ccccc2)CCO1,,O,,O=C(O)C(F)(F)F,,test
US04521422,CCC(=O)Nc1cccc(C(=O)C=CN(C)C)c1.Nc1n[nH]cc1C(=O)c1ccccc1>>CCC(=O)Nc1cccc(-c2ccnc3c(C(=O)c4ccccc4)cnn23)c1,,CC(=O)O,,,,test
US20160009710A1,C1COCCN1.NNc1cc(OCC23CC4CC(CC(C4)C2)C3)c(Br)cn1.O=C=NS(=O)(=O)Cl>>O=S(=O)(Nc1nnc2cc(OCC34CC5CC(CC(C5)C3)C4)c(Br)cn12)N1CCOCC1,,C1CCOC1,CCOC(C)=O,,,test
US20100331293A1,CC(C)c1c(-c2ccccn2)nc2cc(F)ccc2c1Cl.Nc1cncc(N2CCOCC2)c1>>CC(C)c1c(-c2ccccn2)nc2cc(F)ccc2c1Nc1cncc(N2CCOCC2)c1,,Cc1ccccc1,,,,test
US20080188527A1,O=Cc1ccc(-c2cccnc2)o1>>OCc1ccc(-c2cccnc2)o1,,CO,,[BH4-].[Na+],,test
US05210209,NOS(=O)(=O)O.Nc1nc2ccccc2[nH]1>>Nc1nc2ccccc2n1N,,O,,[K+].[OH-],,test
US20050192347A1,CC(CCCCCN)(COC1CCCCO1)c1ccccc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(CCCCCN=C=O)(COC1CCCCO1)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20080194833A1,CCCCOC(=O)[C@H](CC)OS(=O)(=O)C(F)(F)F.COc1ccc(OCCCN(Cc2cccc(O)c2)c2nc3ccccc3o2)cc1>>CCCCOC(=O)[C@@H](CC)Oc1cccc(CN(CCCOc2ccc(OC)cc2)c2nc3ccccc3o2)c1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US04517184,Cc1cc(O)c(O)cc1C(=O)c1cccnc1.O=C(O)C(Br)Br>>Cc1cc2c(cc1C(=O)c1cccnc1)OC(C(=O)O)O2,,CS(C)=O,O,,,test
US20110092505A1,CC(C)(C)OC(=O)N1CCN(c2cc(CO)cc(-c3ccnc(NC4CCCCC4)c3)n2)CC1>>OCc1cc(-c2ccnc(NC3CCCCC3)c2)nc(N2CCNCC2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130150343A1,C=CCN(CC=C)c1nnc2ccc(F)cn12.N[C@H]1CC[C@@H](O)c2ccccc21>>C/C=C/N(/C=C/C)c1nnc2ccc(O[C@@H]3CC[C@H](N)c4ccccc43)cn12,,CN(C)C=O,,[H-].[Na+],,test
US04855295,CCOC(=O)c1ncc2[nH]c3cccc(O)c3c2c1COC>>CCOC(=O)c1ncc2[nH]c3c(c2c1COC)C(=O)CCC3,[Ni],CCO,,[H][H],,test
US20140296245A1,CO.O=C1C[C@@H](c2ccc(F)c(C(F)(F)F)c2)[C@H](C(=O)O)CN1>>COC(=O)[C@@H]1CNC(=O)C[C@H]1c1ccc(F)c(C(F)(F)F)c1,,CCOCC,CO,C[Si](C)(C)C=[N+]=[N-],,test
US04128429,CCCCN(CCO)CCCC.CCCC[Sn](CCCC)(CCCC)O[Sn](CCCC)(CCCC)CCCC>>CCCCN(CCCC)CCO[Sn](CCCC)(CCCC)CCCC,,c1ccccc1,,O,,test
US06313116B1,CCc1nc2c(OC)ccc(C(=O)O)c2s1.Cc1noc(C)c1N>>CCc1nc2c(OC)ccc(C(=O)Nc3c(C)noc3C)c2s1,,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20100190766A1,COC(=O)c1ccc(N2CCC(c3ccc(CN4CCOCC4)cc3)CC2)cc1>>O=C(O)c1ccc(N2CCC(c3ccc(CN4CCOCC4)cc3)CC2)cc1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20110224211A1,CC(C)(C)OC(=O)N1CCC[C@H]1c1nc(-c2ccc(-c3ccc(-c4c[nH]c([C@@H]5COC6(CCOCC6)N5C(=O)OCc5ccccc5)n4)cc3)cc2)c[nH]1>>O=C(OCc1ccccc1)N1[C@H](c2nc(-c3ccc(-c4ccc(-c5c[nH]c([C@@H]6CCCN6)n5)cc4)cc3)c[nH]2)COC12CCOCC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US04489091,CCCC(=O)C=[N+]=[N-].Cc1cc(C)c(S(=O)(=O)O)c(C)c1C>>CCCC(=O)COS(=O)(=O)c1c(C)cc(C)c(C)c1C,,CCOCC,,,,test
US20040014962A1,CC(C)(C)[Si](OC1CN(c2nc(C(=O)NCCNC(=O)OCc3ccc([N+](=O)[O-])cc3)cs2)C1)(c1ccccc1)c1ccccc1>>O=C(NCCNC(=O)c1csc(N2CC(O)C2)n1)OCc1ccc([N+](=O)[O-])cc1,,C1CCOC1,,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05594004,CN(CC(=O)c1ccc(OCC(=O)OC(C)(C)C)c(OCC(=O)OC(C)(C)C)c1)C(=O)[C@@H]1CC[C@@H](C#N)CC1.S>>CN(CC(=O)c1ccc(OCC(=O)O)c(OCC(=O)O)c1)C(=O)[C@@H]1CC[C@@H](C(N)=S)CC1,,CCOC(C)=O,,CCN(CC)CC,c1ccncc1,test
US20050159421A1,Cc1nc(C(=O)N(C)CCNC(=O)C(F)(F)F)c(-c2ccc(F)cc2)s1>>Cc1nc(C(=O)N(C)CCN)c(-c2ccc(F)cc2)s1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20140343294A1,O=C(O)CCC=Cc1ccsc1>>O=C(O)CCCCc1ccsc1,,CCO,,[H][H],,test
US20070010670A1,COC(=O)c1cccc2c1OCCN2C(=O)c1cc(Cl)c(O)c(Cl)c1>>O=C(O)c1cccc2c1OCCN2C(=O)c1cc(Cl)c(O)c(Cl)c1,,C1CCOC1,CO,[Na+].[OH-],,test
US05498724,CCOC(=N)NC(=O)OCc1ccccc1.NCCCCCCCCN>>N=C(NCCCCCCCCN)NC(=O)OCc1ccccc1,,Cc1ccccc1,,,,test
US04615725,CC(C)(COc1ccc(Cl)cc1)C1(C)CCC(CBr)O1.C[C@H]1CNC[C@@H](C)C1>>C[C@@H]1C[C@H](C)CN(CC2CCC(C)(C(C)(C)COc3ccc(Cl)cc3)O2)C1,,CCOCC,,,,test
US20060247320A1,CC(C)(C)C1CCc2nc3sc(S(C)(=O)=O)cc3cc2C1.C[Si](C)(C)CI>>CC(C)(C)C1CCc2nc3sc(S(=O)(=O)CC[Si](C)(C)C)cc3cc2C1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20150065482A1,COC(=O)c1nn(-c2cccc(C#C[C@]3(O)CCN(C)C3=O)c2)c2ccc(CO)cc12.N>>CN1CC[C@@](O)(C#Cc2cccc(-n3nc(C(N)=O)c4cc(CO)ccc43)c2)C1=O,,CO,,,,test
US04661488,CC1(C)[C@@H](C(=O)[O-])[C@@H]1c1cnc(C2CCCCC2)nc1.N#CC(O)c1cccc(Oc2ccccc2)n1>>CC1(C)[C@@H](C(=O)OC(C#N)c2cccc(Oc3ccccc3)n2)[C@@H]1c1cnc(C2CCCCC2)nc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20130059834A1,CC1(N)CC1.Cn1nc(-c2cnc3[nH]cc(C(=O)O)c3n2)c2ccc(F)cc21>>Cn1nc(-c2cnc3[nH]cc(C(=O)NC4(C)CC4)c3n2)c2ccc(F)cc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120309746A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.C[C@H]1CCCN1c1cccc(Nc2cc(-c3cccc(CN)c3)cn3ncnc23)n1>>C[C@H]1CCCN1c1cccc(Nc2cc(-c3cccc(CNC4CCN(C(=O)OC(C)(C)C)CC4)c3)cn3ncnc23)n1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100105744A1,CSCc1cccc2c(C(c3ccc(F)cc3)c3ccc(F)cc3F)c[nH]c12.O=C(OO)c1cccc(Cl)c1>>CS(=O)Cc1cccc2c(C(c3ccc(F)cc3)c3ccc(F)cc3F)c[nH]c12,,CO,,ClCCl,,test
US06133290,CN1CC=C(c2c[nH]c3ccc(Br)cc23)CC1>>CN1CCC(c2c[nH]c3ccc(Br)cc23)CC1,O=[Pt],C1CCOC1,,[H][H],,test
US20050176705A1,COc1ccc2c(ccn2S(=O)(=O)c2ccc(C)cc2)c1.O=[N+]([O-])O>>COc1ccc2c(ccn2S(=O)(=O)c2ccc(C)cc2)c1[N+](=O)[O-],,ClCCl,,,,test
US20110135601A1,CN(C)CC1CCc2ccccc2C1.CNC>>CN(C)C1CCc2ccccc2C1,,C1CCOC1,,CO,,test
US20030118916A1,Cc1cc[n+](C)c2ccccc12.Cn1cccc1C=O.O=S(=O)([O-])C(F)(F)F>>CN1CC=C(C=Cc2cccn2C)c2ccccc21.O=S(=O)(O)C(F)(F)F,,CCO,,C1CCNCC1,,test
US20120101083A1,CCCNc1ncc(-c2nc(-c3ccc4c(c3C)CCN(C(=O)OC(C)(C)C)CC4)no2)cc1C#N.O=C(O)C(F)(F)F>>CCCNc1ncc(-c2nc(-c3ccc4c(c3C)CCNCC4)no2)cc1C#N.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20130330773A1,BrP(Br)Br.COC(=O)c1ccc(-c2cccc(CO)c2)cc1>>COC(=O)c1ccc(-c2cccc(CBr)c2)cc1,,ClCCl,,,,test
US20100305096A1,CC(C)(C)OC(=O)N1CC(N2CC(O)C2)C1>>OC1CN(C2CNC2)C1,,ClCCl,O=C(O)C(F)(F)F,,,test
US04390697,CCOC(=O)N1CCN(CCCCN)CC1.Cc1ccc2nc(NN)n(N)c(=O)c2c1>>CCOC(=O)N1CCN(CCCCNC2N=c3ccc(C)cc3=CN2N)CC1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20110275611A1,Clc1ccc2[nH]c(C3CNCCO3)nc2c1.Nc1nc(Cl)cc(Cl)n1>>Nc1nc(Cl)cc(N2CCOC(c3nc4cc(Cl)ccc4[nH]3)C2)n1,,CCO,,CCN(C(C)C)C(C)C,,test
US20150299189A1,C=C(C)c1cnc(Cl)c(C(=O)OC)c1>>COC(=O)c1cc(C(C)C)cnc1Cl,[Pd],CO,,,,test
US04666911,CN=C=O.NC(=O)N1CCN(c2ccccc2)CC1>>CNC(=O)NC(=O)N1CCN(c2ccccc2)CC1,,O,,ClCCl,,test
US20100009974A1,NC1CC1.NS(=O)(=O)c1cc([N+](=O)[O-])ccc1Cl>>NS(=O)(=O)c1cc([N+](=O)[O-])ccc1NC1CC1,,C1COCCO1,,,,test
US20060148778A1,CC(C)(C)[Si](C)(C)OC1C(=O)C=CC2(CC(=O)N2OCc2ccccc2)C1O[Si](C)(C)C.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C1C=CC2(CC(=O)N2OCc2ccccc2)C(O[Si](C)(C)C)C1O[Si](C)(C)C(C)(C)C,,C1CCOC1,,[Li]CCCC,,test
US04394515,COC(=O)c1ccc2c(c1)Sc1ccccc1CC2>>O=C(O)c1ccc2c(c1)Sc1ccccc1CC2,,CCO,,[Na+].[OH-],,test
US20060211714A1,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cc(OCc2ccccc2)cc2ncnc(Cl)c12.Nc1ccc(F)c(Cl)c1>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cc(OCc2ccccc2)cc2ncnc(Nc3ccc(F)c(Cl)c3)c12,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090012093A1,CCC(=O)Cl.Nc1nc2c(s1)CCc1ccccc1-2>>CCC(=O)Nc1nc2c(s1)CCc1ccccc1-2,,c1ccncc1,,O,,test
US20160016938A1,COC(=O)c1ccc2c(C(C)O)nn(-c3ncc(-c4cc(C)ccc4F)cn3)c2c1>>Cc1ccc(F)c(-c2cnc(-n3nc(C(C)O)c4ccc(C(=O)O)cc43)nc2)c1,,C1CCOC1,O,[Li+].[OH-],,test
US04158060,O=[N+]([O-])C=C1CCCN1Cc1ccc(F)cc1>>NCC1CCCN1Cc1ccc(F)cc1,[Ni],CO,,,,test
US20090137580A1,Cn1c(C(C)(C)O[Si](C)(C)C)cc2ncnc(Oc3ccc(N)c(Cl)c3)c21.O=C=Nc1cccc(C(F)(F)F)c1>>Cn1c(C(C)(C)O[Si](C)(C)C)cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(Cl)c3)c21,,C1CCOC1,,CCN(CC)CC,O,test
US20040067955A1,CC(C)n1nc(-c2cc(O)cnc2-c2ccccc2)ccc1=O.O=C1c2ccccc2C(=O)N1CCCBr>>CC(C)n1nc(-c2cc(OCCCN3C(=O)c4ccccc4C3=O)cnc2-c2ccccc2)ccc1=O,,CN(C)C=O,,O,[H-].[Na+],test
US20120238613A1,CI.O=C1N(c2ccc([C@@H](O)C(F)(F)F)cc2)CCC12CCC1(CC2)OCCO1>>CO[C@H](c1ccc(N2CCC3(CCC4(CC3)OCCO4)C2=O)cc1)C(F)(F)F,,CN(C)C=O,,[H-].[Na+],,test
US20070037877A1,Cc1cc(=O)oc2ccc(O)cc12.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1cc(=O)oc2ccc(OS(=O)(=O)C(F)(F)F)cc12,,ClCCl,,CCOC(C)=O,c1ccncc1,test
US20120283239A1,CN.Cn1nnc2c(C#N)nc(-c3ccc(CCC=O)c(C(F)(F)F)c3)cc21>>CNCCCc1ccc(-c2cc3c(nnn3C)c(C#N)n2)cc1C(F)(F)F,,C1CCOC1,CCOC(C)=O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20050153962A1,N=CN.S=C=NC1(Cl)C=CC=CC1>>NC=NC(=S)Nc1ccc(Cl)cc1,,C1CCOC1,,Cl,[Na+].[OH-],test
US06518257B1,CC(=O)O.O=[N+]([O-])c1cc(Br)ccc1F>>CC(=O)Nc1cc(Br)ccc1F,[Fe],CC(=O)O,,CC(=O)OC(C)=O,,test
US20120258948A1,C[C@@](CCn1ccc(-c2ccc(N3CCC(CO)CC3)cc2)cc1=O)(C(=O)NOC1CCCCO1)S(C)(=O)=O.Cl>>C[C@@](CCn1ccc(-c2ccc(N3CCC(CO)CC3)cc2)cc1=O)(C(=O)NO)S(C)(=O)=O.Cl,,CO,ClCCl,C1COCCO1,,test
US20090233900A1,CN1C(=O)CCc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3NC3CCNCC3)cc21.ClCCCl.O=CC1CC1>>CN1C(=O)CCc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3NC3CCN(CC4CC4)CC3)cc21.Cl,,CC(=O)O,,[Na+].[OH-],,test
US06262095B1,O=C1c2ccccc2C(=O)c2sc(-c3ccco3)nc21.O=[N+]([O-])O>>O=C1c2ccccc2C(=O)c2sc(-c3ccc([N+](=O)[O-])o3)nc21,,O=S(=O)(O)O,,,,test
US20040102481A1,CN1CCC(c2c[nH]c3ccc(O)cc23)CC1.O=S(=O)(Cl)c1ccccc1F>>CN1CCC(c2c[nH]c3ccc(OS(=O)(=O)c4ccccc4F)cc23)CC1,,C1CCOC1,,[Na+].[OH-],,test
US20090042890A1,CCOC(=O)c1nc(NCCO)nc(Nc2ccccc2OC)c1N.CCOC(=O)c1nc(NCCO)nc(Nc2ccccc2OC)c1[N+](=O)[O-]>>COc1ccccc1-n1c(=O)[nH]c2c(C(N)=O)nc(NCCO)nc21,[Pd],,,CCO,,test
US20150057265A1,C=C(C)c1cnc2c(NC(=O)OC(C)(C)C)c(C(=O)OCC)oc2c1>>CCOC(=O)c1oc2cc(C(C)C)cnc2c1NC(=O)OC(C)(C)C,[Pd],CO,,,,test
US20080275097A1,COc1ccc(CNc2ccc3c(CO)nn(Cc4ccc(OC)cc4)c3n2)cc1.O=S(Cl)Cl>>COc1ccc(CNc2ccc3c(CCl)nn(Cc4ccc(OC)cc4)c3n2)cc1,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20100204221A1,CC1(C)OB(c2cccc(CC#N)c2)OC1(C)C.Clc1nc(Cl)c2ccsc2n1>>N#CCc1cccc(-c2nc(Cl)nc3sccc23)c1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20040235822A1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3C(=O)C(F)(F)F)cc1,,C1CCOC1,CCN(CC)CC,Cl,O=C([O-])O.[Na+],test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Nc1ccc2oc(=O)[nH]c2c1>>COc1ccc2nc(Nc3ccc4oc(=O)[nH]c4c3)c3[nH]ncc3c2c1,C1COCCO1,CO,,Cl,,test
US05106871,COCOc1ccc(CCC(=O)c2c(OC)cc(OC)c(CCC(C)C)c2OCC(=O)OC)cc1OC>>COC(=O)COc1c(CCC(C)C)c(OC)cc(OC)c1C(=O)CCc1ccc(O)c(OC)c1,,CO,,Cl,,test
US20070010511A1,BrC(Br)(Br)Br.COCCCn1ccnc1>>COCCCn1ccnc1Br,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20050208582A1,O=P(Cl)(Cl)Cl.c1ccc(C(c2ccccc2)(c2ccccc2)n2nc(-c3ccc4ccccc4c3)c3ncccc32)cc1>>Clc1ccc2[nH]nc(-c3ccc4ccccc4c3)c2n1,,Cc1ccccc1,,,,test
US05919793,O=C(O)Cc1ccc(I)cc1.O=S(Cl)Cl>>O=C(Cl)Cc1ccc(I)cc1,CN(C)C=O,ClCCl,,,,test
US20140200216A1,CCOC(=O)c1nc2cc(N3CCOCC3)ccc2cc1NC(=O)OCc1ccccc1>>O=C(Nc1cc2ccc(N3CCOCC3)cc2nc1C(=O)O)OCc1ccccc1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20040167174A1,CCOc1cc(C(CC(=O)NO)N2C(=O)c3ccccc3C2=O)ccc1OC.O=C(Cl)c1cccnc1>>CCOc1cc(C(CC(=O)NOC(=O)c2cccnc2)N2C(=O)c3ccccc3C2=O)ccc1OC,,CC#N,,CCN(CC)CC,Cl,test
US20100216767A1,CNC(=O)COc1cc(Br)cc([N+](=O)[O-])c1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>CNC(=O)COc1cc(-c2cnn(C)c2)cc([N+](=O)[O-])c1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US05712267,C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(S[C@H]3C[C@@H](C(=O)N4CCN(C(=O)OCc5ccc([N+](=O)[O-])cc5)C(C(=O)OCc5ccc([N+](=O)[O-])cc5)C4)N(C(=O)OCc4ccc([N+](=O)[O-])cc4)C3)[C@H](C)[C@H]12>>C[C@@H](O)[C@H]1C(=O)N2C(C(=O)O)=C(S[C@@H]3CN[C@H](C(=O)N4CCNC(C(=O)O)C4)C3)[C@H](C)[C@H]12,,C1CCOC1,O,,,test
US20130116250A1,Nc1ccc(C(=O)c2nc(Br)c3ccccn23)cc1C(=O)O.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=C(c1ccc2[nH]c(=O)oc(=O)c2c1)c1nc(Br)c2ccccn12,,C1COCCO1,,,,test
US04067724,CSc1nnc(C(C)(C)C)c(=O)n1N.O=CC(=O)O>>CSc1nnc(C(C)(C)C)c(=O)n1NC(O)C(=O)O,,CCOC(C)=O,,O,,test
US20100210619A1,C1CCC(NCC2CC2)CC1.Cc1cc(S(=O)(=O)NCCC(=O)OC(C)(C)C)ccc1NC(=O)c1cc(Cl)ncn1>>Cc1cc(S(=O)(=O)NCCC(=O)OC(C)(C)C)ccc1NC(=O)c1cc(N(CC2CC2)C2CCCCC2)ncn1,,CCO,,CC(C)NC(C)C,,test
US20110046170A1,CO.Cc1cc(C(=N)NO)nc(Cl)n1>>COc1nc(C)cc(C(=N)NO)n1,,O,,[H-].[Na+],,test
US20040102437A1,CO.NCCNc1ccccc1.O=C1CCC(Nc2ccc3[nH]ncc3c2)CC1>>CCCCCNC1CCC(Nc2ccc3[nH]ncc3c2)CC1,,CO,,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05082954,CC[Si](CC)(CC)c1cc(C=O)c(C)o1>>CC[Si](CC)(CC)c1cc(CO)c(C)o1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04468517,CN(C)CC(N)=S.Cl.O=C(CCl)CCl>>CN(C)Cc1nc(CCl)cs1.Cl,,ClCCCl,,O=C([O-])O.[Na+],,test
US05246929,O=C([C@@H]1CCCN1S(=O)(=O)c1ccc2ccccc2c1)N1C[C@@H](c2ccc(Cl)cc2)Sc2ccccc21>>Clc1ccc([C@@H]2CNc3ccccc3S2)cc1,,CCO,O,[K+].[OH-],,test
US20020107278A1,CC(C)(C)OC(=O)N1CCc2[nH]c3cccc(-c4c(F)cccc4F)c3c2CC1>>Fc1cccc(F)c1-c1cccc2[nH]c3c(c12)CCNCC3,,O=C(O)C(F)(F)F,,ClCCl,,test
US20090227575A1,Clc1nc(N2CCOCC2)c2ccc3c(ccn3Cc3ccccc3)c2n1.OCc1cccc(B(O)O)c1>>OCc1cccc(-c2nc(N3CCOCC3)c3ccc4c(ccn4Cc4ccccc4)c3n2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US04387103,COC(=O)c1ccccc1O.ClCC1CO1>>COC(=O)c1ccccc1OCC1CO1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030078236A1,CCNc1ccc(C(=O)OC)cn1.SC(c1ccccc1)c1ccccc1CBr>>COC(=O)c1ccc(NCCCc2ccccc2SCc2ccccc2)nc1,,CN(C)C=O,,[H-].[Na+],,test
US05677302,CCCCn1sc2nc3ccccc3n2c1=O.COC(=O)c1ccc(C#N)cc1>>COC(=O)c1ccc(-c2nsc3nc4ccccc4n23)cc1,,ClCCl,,,,test
US20030125371A1,CCOC(=O)C(=O)c1cn(Cc2ccccc2)c2ccc(-c3ccccc3)cc12>>O=C(O)C(=O)c1cn(Cc2ccccc2)c2ccc(-c3ccccc3)cc12,,C1CCOC1,O,[K+].[OH-],,test
US20070191370A1,Nc1nc(Cl)cc(Cl)n1.OC(C1CCCCC1)C(F)(F)F>>Nc1nc(Cl)cc(OC(C2CCCCC2)C(F)(F)F)n1,,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US20150291595A1,COc1ccc(N)cc1F.O=C(Cl)c1c(Cl)ncnc1Cl>>COc1ccc(NC(=O)c2c(Cl)ncnc2Cl)cc1F,,ClCCl,,,,test
US03931407,COc1cccc(C(=O)CC2CCCCC2=O)c1.Nc1ccc(O)c(C(=O)O)c1>>COc1cccc(-c2cc3c(n2-c2ccc(O)c(C(=O)O)c2)CCCC3)c1,,CC(=O)O,,,,test
US20100160362A1,COc1ccc2c(n1)C1(CO2)C(=O)N(Cc2ccc(C(F)(F)F)o2)c2cccc(Br)c21.OB(O)c1ccoc1>>COc1ccc2c(n1)C1(CO2)C(=O)N(Cc2ccc(C(F)(F)F)o2)c2cccc(-c3ccoc3)c21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20140323498A1,CCOC(=O)c1cc2cc(N3CCN(CCCCc4c[nH]c5ccc(C#N)cc45)CC3)ccc2o1.NC=O>>N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc5oc(C(N)=O)cc5c4)CC3)c2c1,,C1CCOC1,CO,O,C[O-].[Na+],test
US04129700,CCO.CCOC(=O)OOC(C)(C)CC(C)OC(=O)Cl>>CCOC(=O)OOC(C)(C)CC(C)OC(=O)OCC,,CCOCC,,c1ccncc1,,test
US20160159774A1,C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CNC4)ncc2F)C1.O=CC1CC1>>C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(CC3CC3)C4)ncc2F)C1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20140142199A1,CCC(CO)(CO)C(=O)O.COC(C)(C)OC>>CCC1(C(=O)O)COC(C)(C)OC1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20030008849A1,CC#CCOc1ccc(S(=O)(=O)N2CCSC(C)(C)C2C(=O)[O-])cc1>>CC#CCOc1ccc(S(=O)(=O)N2CCSC(C)(C)C2C(=O)O)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150307463A1,Cc1ccccc1O.NC(=O)c1cc(-c2ccc(CBr)cc2)no1>>Cc1ccccc1OCc1ccc(-c2cc(C(N)=O)on2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20030153606A1,COc1ccc(C=O)cc1-c1cc2c(cc1C)C(C)(C)CCC2(C)C.O=C1CNC(=O)N1>>COc1ccc(C=C2NC(=O)NC2=O)cc1-c1cc2c(cc1C)C(C)(C)CCC2(C)C,,CCO,,C1CCNC1,,test
US20090264420A1,CC(C)(C)C(Br)C(=O)N(Cc1ccc(F)cc1)Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>CC(C)(C)C1C(=O)N(Cc2ccc(F)cc2)Cc2cncn21,,CC#N,,,,test
US20080306082A1,CC(C)(C)OC(=O)N1CCC(CCCN)CC1.CCN(C(C)C)C(C)C.NC(=O)c1cccc2sc(-c3nc(Cl)ncc3Cl)cc12>>CC(C)(C)OC(=O)N1CCN(CCCNc2ncc(Cl)c(-c3cc4c(C(N)=O)cccc4s3)n2)CC1,,C1COCCO1,,CC(=O)N(C)C,,test
US20110224257A1,O=C(Cn1nc(C(F)F)cc1C(F)F)N1CCC(c2nc(C3=NOC(c4ccccc4[N+](=O)[O-])C3)cs2)CC1>>Nc1ccccc1C1CC(c2csc(C3CCN(C(=O)Cn4nc(C(F)F)cc4C(F)F)CC3)n2)=NO1,[Pd],CO,,,,test
US06172065B2,Cc1ccc2[nH]c(=O)c(=O)[nH]c2c1CN(C)Cc1ccccc1>>CNCc1c(C)ccc2[nH]c(=O)c(=O)[nH]c12,[Pd],CN(C)C=O,,,,test
US20100125062A1,Cn1c(Nc2ccc(O)cc2)nc2ccccc21.O=Cc1cccnc1Cl>>Cn1c(Nc2ccc(Oc3ncccc3C=O)cc2)nc2ccccc21,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04948796,O=S(Cl)Cl.OC1c2ccccc2CCc2ncccc21>>Cl.ClC1c2ccccc2CCc2ncccc21,,ClCCl,,O,,test
US20040097732A1,CCCCC1CNC(=O)C1CN(C=O)OCc1ccccc1.O=C(Cl)c1ccccc1>>CCCCC1CN(C(=O)c2ccccc2)C(=O)C1CN(C=O)OCc1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20090082329A1,CC1(C)C(=O)N(c2ccc(S(=O)(=O)C(F)(F)F)cc2)C(=O)N1Cc1ccnc(N)n1.O=C(Cl)Oc1ccccc1>>CC1(C)C(=O)N(c2ccc(S(=O)(=O)C(F)(F)F)cc2)C(=O)N1Cc1ccnc(NC(=O)Oc2ccccc2)n1,,C1CCOC1,CCOC(C)=O,c1ccncc1,,test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2cc(-c3cc(CN4CCN(C(=O)OC(C)(C)C)CC4)cnc3F)nc(C)n2)cc1.CS(=O)(=O)Cl>>COc1ccc(CN(Cc2ccc(OC)cc2)c2cc(-c3cc(CN4CCN(S(C)(=O)=O)CC4)cnc3F)nc(C)n2)cc1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20150191452A1,CC(C)(C)OC(=O)N1CCCC(=O)CC1.COc1ccc(Br)cc1>>COc1ccc(C2(O)CCCN(C(=O)OC(C)(C)C)CC2)cc1,,C1CCOC1,,[Li]CCCC,,test
US20110294850A1,BrCCc1ccccc1.COc1ccc2c(c1)CCN2>>COc1ccc2c(ccn2CCc2ccccc2)c1,,CN(C)C=O,,[H-].[Na+],,test
US20060084680A1,CCCN(CCCOc1ccc2c(c1)CC[C@H]2CC(=O)OCC)c1ccc(C#N)cn1.S>>CCCN(CCCOc1ccc2c(c1)CC[C@H]2CC(=O)OCC)c1ccc(C(N)=S)cn1,,CN(C)C=O,,CCNCC,,test
US20030087901A1,COc1ccc2c(c1)CCN(c1ccc(NC(C)=O)cc1)C2Cc1ccc(OCc2ccccc2)cc1>>COc1ccc2c(c1)CCN(c1ccc(NC(C)=O)cc1)C2Cc1ccc(O)cc1,[Pd],C1CCOC1,CCO,,,test
US20100234389A1,Fc1ccc(-c2cc(N3CCNCC3)ccn2)c(F)c1.O=C([O-])Nc1cccnn1>>O=C(Nc1cccnn1)N1CCN(c2ccnc(-c3ccc(F)cc3F)c2)CC1,,C1CCOC1,CCCCCC,,,test
US05068325,ClCC=Cc1cccc(Cl)c1.Nc1nc2c(s1)CCNCC2>>Nc1nc2c(s1)CCN(CC=Cc1cccc(Cl)c1)CC2,,ClC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US20030176400A1,Cc1cc2c(CC(=O)O)cccc2n1C(=O)OC(C)(C)C>>Cc1cc2c(CC(=O)O)cccc2[nH]1,,CO,,O,[Na+].[OH-],test
US20150011551A1,COC(=O)c1ccc2ncc(NS(=O)(=O)c3cc(Br)ccc3OC)cc2c1>>COc1ccc(Br)cc1S(=O)(=O)Nc1cnc2ccc(C(=O)O)cc2c1,,C1CCOC1,O,[Li+].[OH-],,test
US20100145054A1,ClCCCCI.c1ccc(-c2nc3ccccc3[nH]2)cc1>>ClCCCCn1c(-c2ccccc2)nc2ccccc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05142056,CC(C)[C@H](N)C(=O)OCc1ccccc1.Cc1ccc(S(=O)(=O)O)cc1.ClCc1cccnc1>>CC(C)[C@H](NC(=O)c1cccnc1)C(=O)OCc1ccccc1,,CCOCC,ClCCl,CN1CCOCC1,Cl,test
US20140221370A1,CC(C)(C)OC(=O)NCC(=O)N1CCN(c2ccnc3[nH]cc(NC(=O)c4cccnc4)c23)CC1>>NCC(=O)N1CCN(c2ccnc3[nH]cc(NC(=O)c4cccnc4)c23)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140378686A1,CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(F)cc(F)c3C[C@H]2O)C1.CI>>CO[C@@H]1Cc2c(F)cc(F)cc2[C@H]1n1nc(-c2cccc(C#N)c2)c2c1CCN(C(C)=O)C2,,CN(C)C=O,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20160237091A1,COc1ncc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3cc4c(cc23)CN(Cc2cccc(Cl)c2)CC(=O)N4)cn1>>COc1ncc(-c2n[nH]c3cc4c(cc23)CN(Cc2cccc(Cl)c2)CC(=O)N4)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070161637A1,CC(C)(C)c1ccc(Nc2cc(Cl)nc(N)n2)cc1.OCc1ccccc1C(F)(F)F>>CC(C)(C)c1ccc(Nc2cc(OCc3ccccc3C(F)(F)F)nc(N)n2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20050267093A1,C#Cc1ccccn1.O=C=O>>O=C(O)C#Cc1ccccn1,,C1CCOC1,,[Li]CCCC,,test
US04585774,COC(=O)c1ccccc1NC(=O)CN1CCNCC1.COc1ccc(C(=O)Cl)cc1OC>>COC(=O)c1ccccc1NC(=O)CN1CCN(C(=O)c2ccc(OC)c(OC)c2)CC1,,ClCCl,,CCN(CC)CC,,test
US20160009740A1,CCCCCC(O)C=CB1OC(C)(C)C(C)(C)O1>>CCCCCC(O)/C=C/B(O)O,,CC(C)=O,O,,,test
US20130029970A1,COc1ccc(C(=O)c2cc3cc(C)n(CCCCl)c3s2)cc1.[N-]=[N+]=[N-]>>COc1ccc(C(=O)c2cc3cc(C)n(CCCN=[N+]=[N-])c3s2)cc1,,CS(C)=O,,O,,test
US20040132727A1,COc1cc2ncnc(Oc3ccc(N)c([N+](=O)[O-])c3)c2cc1OC.NCCN1CCOCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2ncnc(Oc3ccc(NC(=O)NCCN4CCOCC4)c([N+](=O)[O-])c3)c2cc1OC,,ClC(Cl)Cl,O,CCN(CC)CC,,test
US20090131420A1,O=C1COCC(Cc2ccc(O)cc2)N1.O=[N+]([O-])c1ccc(F)cc1>>O=C1COCC(Cc2ccc(Oc3ccc([N+](=O)[O-])cc3)cc2)N1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160200725A1,CNc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)c(=O)n(CC[N+]3([O-])CCN(C(=O)OC(C)(C)C)CC3)c2n1>>CNc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)c(=O)n(CCN3CCN(C(=O)OC(C)(C)C)CC3)c2n1,,CN(C)C=O,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20030176477A1,C=O.NC(=O)c1snc(Cl)c1Cl>>O=C(NCO)c1snc(Cl)c1Cl,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040242890A1,CCOC(=O)CN=C=O.Nc1cccc(I)c1>>CCOC(=O)CNC(=O)Nc1cccc(I)c1,,ClCCl,,CCO,,test
US20090029958A1,O=C(O)COCCc1cccc(Cl)c1Cl.OC1CCNCC1>>O=C(COCCc1cccc(Cl)c1Cl)N1CCC(O)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06174839B1,CC1Cc2c(c(C#C[Si](C)(C)C)cc(F)c2-n2c(=O)cc(C(F)(F)F)n(C)c2=O)O1>>C#Cc1cc(F)c(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c2c1OC(C)C2,,CCO,,[F-].[K+],,test
US20160102071A1,CCOC(=O)CC1(c2ccc(OCc3ccc4scc(-c5ccc(N6CC7(CCS7(=O)=O)C6)cc5C)c4c3)cc2)CC(=O)C1>>Cc1cc(N2CC3(CCS3(=O)=O)C2)ccc1-c1csc2ccc(COc3ccc(C4(CC(=O)O)CC(=O)C4)cc3)cc12,,CC#N,,Cl,[Na+].[OH-],test
US20030058697A1,C#Cc1ccccc1-c1cc(OC)c(-c2ccccc2C#C)cc1OC.O>>C#Cc1ccccc1C1=CC(=O)C(c2ccccc2C#C)=CC1=O,,O,,C1CCOC1,,test
US20070191431A1,BrCc1ccccc1.COCC(=O)Nc1cccc(C2(C3CCNCC3)N=C(N)N(C)C2=O)c1>>COCC(=O)Nc1cccc(C2(C3CCN(Cc4ccccc4)CC3)N=C(N)N(C)C2=O)c1,,CC#N,CCO,O=C([O-])[O-].[K+].[K+],,test
US20150282482A1,Nc1ccccc1.O=C(O)c1cc2cc(C(F)(F)F)ccc2s1>>O=C(Nc1ccccc1)c1cc2cc(C(F)(F)F)ccc2s1,CN(C)c1ccncc1,C1CCOC1,,CCN=C=NCCCN(C)C,Cl,test
US06172064B2,C#CC[C@@H](C(=O)O)[C@@H](C)O.NOC1CCCCO1>>C#CC[C@@H](C(=O)NOC1CCCCO1)[C@@H](C)O,,ClCCl,,ClCCCl,,test
US20050143391A1,COC(=O)[C@H](CCC(=O)N1CCC(CN2Cc3ccccc3C2=O)CC1)NC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1>>O=C(O)[C@H](CCC(=O)N1CCC(CN2Cc3ccccc3C2=O)CC1)NC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1,,C1CCOC1,O,[Li]O,,test
US20020015804A1,CCCCCC1CCC(C2CCC(C(CO)CO)CC2)CC1.S=C(Cl)Cl>>CCCCCC1CCC(C2CCC(C3COC(=S)OC3)CC2)CC1,,c1ccncc1,,c1ccccc1,,test
US20130225589A1,CCc1nc(SC)ncc1C(=O)O.Nc1cc(Cl)ccc1Cl>>CCc1nc(SC)ncc1C(=O)Nc1cc(Cl)ccc1Cl,,ClCCl,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20060160851A1,O=C(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)N1CCC(O)CC1.On1cccn1>>O=C(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)N1CCC(On2cccn2)CC1,,CCCCCCC,CCOC(C)=O,,,test
US20130109696A1,BrP(Br)Br.OCc1ccc(C(F)(F)F)cc1-c1ccnnc1>>FC(F)(F)c1ccc(CBr)c(-c2ccnnc2)c1,,ClCCl,,O,,test
US20060106096A1,COC(=O)CS.O=Cc1cccc(Br)c1F>>COC(=O)c1cc2cccc(Br)c2s1,,CS(C)=O,,[H][H],[H-].[Na+],test
US04086423,CC(C)COC(=O)Cl.COC(NC(=O)Cc1cccs1)C(=O)O>>COC(NC(=O)Cc1cccs1)C(=O)OC(=O)OCC(C)C,,ClCCl,,CCN(CC)CC,,test
US05334716,CCO.O=C(O)CC/C=C/c1ccccn1>>CCOC(=O)CC/C=C/c1ccccn1,,CCO,,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US20110301382A1,O=C(O)c1c([N+](=O)[O-])cc(S(F)(F)(F)(F)F)cc1[N+](=O)[O-]>>O=[N+]([O-])c1cc([N+](=O)[O-])cc(S(F)(F)(F)(F)F)c1,,O,,,,test
US03957806,ClCOc1ccccc1Br.Nc1ccccn1>>Nc1cccc[n+]1COc1ccccc1Br.[Cl-],,Cc1ccccc1C,,,,test
US20110306590A1,CNC(=O)c1nccnc1Cl.Clc1ccc2[nH]c(C3CNC3)nc2c1>>CNC(=O)c1nccnc1N1CC(c2nc3cc(Cl)ccc3[nH]2)C1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20060173019A1,Nc1cc(Cl)cnc1Sc1ccncc1.O=S(=O)(Cl)c1ccc(Cl)c(C(F)(F)F)c1>>O=S(=O)(Nc1cc(Cl)cnc1Sc1ccncc1)c1ccc(Cl)c(C(F)(F)F)c1,,c1ccncc1,,,,test
US20120115856A1,CC(C)N.O=[N+]([O-])c1cc(-c2nc3ccccc3o2)ccc1F>>CC(C)Nc1ccc(-c2nc3ccccc3o2)cc1[N+](=O)[O-],,CCO,,O,O=C([O-])[O-].[K+].[K+],test
US20030082510A1,C=C(Cl)CCl.Cc1c(CN2C(=O)c3ccccc3C2=O)c(=O)oc2c(C)c(O)ccc12>>C=C(Cl)COc1ccc2c(C)c(CN3C(=O)c4ccccc4C3=O)c(=O)oc2c1C,,CN(C)C=O,ClCCl,[I-].[K+],,test
US20100234354A1,CC(C)(C)OC(=O)NC/C=C\c1cnc(-c2cccc(Cn3nc(-c4cc(F)c(F)c(F)c4)ccc3=O)c2)nc1>>NC/C=C/c1cnc(-c2cccc(Cn3nc(-c4cc(F)c(F)c(F)c4)ccc3=O)c2)nc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120329649A1,CC(O)(CC(c1cc(Cl)cc(Cl)c1)C(F)(F)F)c1ccc(-n2cncn2)cc1>>C/C(=C\C(c1cc(Cl)cc(Cl)c1)C(F)(F)F)c1ccc(-n2cncn2)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100298341A1,COC(=O)C=O.C[C@@H]1CN(C2(c3ccc(Cl)cc3)CCCCC2)CCN1>>COC(=O)CN1CCN(C2(c3ccc(Cl)cc3)CCCCC2)C[C@H]1C,,ClCCl,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20120035132A1,COCC(COc1nc(Cl)c(Cl)cc1C#N)OC.OB1OCc2cc(O)ccc21>>COCC(COc1nc(Oc2ccc3c(c2)COB3O)c(Cl)cc1C#N)OC,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150038574A1,CC1=C(C=O)C(C)(C)CCC1.Nc1cccc(Cl)c1>>CC1=C(CNc2cccc(Cl)c2)C(C)(C)CCC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US06153726,Cl.O=[N+]([O-])c1c2ccccc2cc2ccccc12>>Cl.Nc1c2ccccc2cc2ccccc12,,CC(=O)O,,,,test
US05532235,Cc1ccc(S(=O)(=O)N2CCCC(=O)c3cccnc32)cc1>>O=C1CCCNc2ncccc21,,CC(=O)O,,O=S(=O)(O)O,[Na+].[OH-],test
US20140018533A1,COC(=O)C1=C(NCc2ccccc2F)OC(=Cc2c[nH]c3ncccc23)C1=O>>O=C1C=C(NCc2ccccc2F)OC1=Cc1c[nH]c2ncccc12,,CCO,,[K+].[OH-],,test
US20160009744A1,CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)O[C@H]1C[C@H](Nc2ncncc2C(=O)c2cc([C@@H]3OCCc4ccc(Cl)cc43)c(C)s2)C[C@@H]1COS(=O)(=O)NC(=O)OC(C)(C)C>>CC[C@H](C)[C@H](N)C(=O)O[C@H]1C[C@H](Nc2ncncc2C(=O)c2cc([C@@H]3OCCc4ccc(Cl)cc43)c(C)s2)C[C@@H]1COS(N)(=O)=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150119587A1,COCOc1ccc(C=O)c(O)c1C.OO>>COCOc1ccc(O)c(O)c1C,,O,,[Na+].[OH-],,test
US04173630,CCCCOc1c(OC)ccc(S(=O)(=O)N[C@@H](CCCNC(=N)N)C(=O)N2CCC(C)CC2C(=O)OCC)c1OC>>CCCCOc1c(OC)ccc(S(=O)(=O)N[C@@H](CCCNC(=N)N)C(=O)N2CCC(C)CC2C(=O)O)c1OC,,CCO,O,CC(=O)O,[Na+].[OH-],test
US20140100366A1,CC(C)(C)OC(=O)Nc1ncc(B(O)O)cn1>>Nc1ncc(B(O)O)cn1,,O,,Cl,[Na+].[OH-],test
US20150191478A1,CC(=O)Nc1cncc(-c2cc3cncc(I)c3o2)c1.CC(C)(C)c1ccc(B(O)O)cc1>>CC(=O)Nc1cncc(-c2cc3cncc(-c4ccc(C(C)(C)C)cc4)c3o2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,O,O=C([O-])[O-].[Na+].[Na+],,test
US04050921,Cc1ccccc1CSc1cccc[n+]1[O-].O=C(OO)c1cccc(Cl)c1>>Cc1ccccc1CS(=O)c1cccc[n+]1[O-],,ClC(Cl)Cl,,,,test
US20140213615A1,CC(=O)c1ccncc1.Cc1[nH]c2cc(C(=O)c3ccccc3)ccc2c1C=O>>Cc1[nH]c2cc(C(=O)c3ccccc3)ccc2c1/C=C/C(=O)c1ccncc1,,CO,,C1CCNCC1,,test
US20130261158A1,BrCCOc1ccc(-c2ccccc2)cc1.NC1CC1>>c1ccc(-c2ccc(OCCNC3CC3)cc2)cc1,,C1CCOC1,,,,test
US20140378433A1,CC(C)(C)OC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)c(F)c1.CCN1CC(C)(C)Oc2nc(SC)nc(Cl)c2C1=O>>CCN1CC(C)(C)Oc2nc(SC)nc(-c3ccc(NC(=O)OC(C)(C)C)cc3F)c2C1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20090156603A1,CC(C)(C)OC(=O)N1CCC(C(Cl)=NOS(C)(=O)=O)C1.Nc1ncc(Br)cc1Oc1ccccc1.[Na]N=C=S>>CC(C)(C)OC(=O)N1CCC(c2nsc(Nc3ncc(Br)cc3Oc3ccccc3)n2)C1,,CC#N,O,c1ccncc1,,test
US20140005175A1,CC(C)(C(=O)Nc1ccccc1O)c1ccc(S(=O)(=O)/C=C/C#N)cc1>>CC(C)(c1ccc(S(=O)(=O)/C=C/C#N)cc1)c1nc2ccccc2o1,,C1COCCO1,,CS(=O)(=O)O,,test
US20090176786A1,CC(=O)Cl.CN(C(=O)NC(=O)c1c(F)cccc1F)c1ccc(SC(F)(F)F)cc1F>>CC(=O)N(C(=O)c1c(F)cccc1F)C(=O)N(C)c1ccc(SC(F)(F)F)cc1F,,CN1CCCC1=O,,[H-].[Na+],,test
US20090023707A1,COC(=O)c1coc(-c2ccc(Cn3cnc4ccccc43)cc2)n1>>OCc1coc(-c2ccc(Cn3cnc4ccccc43)cc2)n1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070191293A1,COc1ccc(C2OC[C@@H]3C[C@@H](n4ccc5c(SCc6ccccc6)ncnc54)[C@H](OC(=S)Oc4ccccc4)[C@@H]3O2)cc1>>COc1ccc(C2OC[C@@H]3C[C@@H](n4ccc5c(SCc6ccccc6)ncnc54)C[C@@H]3O2)cc1,,Cc1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,CCCC[SnH](CCCC)CCCC,test
US20100310512A1,Brc1ccc(Br)cc1.COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1)C(C)C>>COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(-c3ccc(Br)cc3)cc2)[nH]1)C(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,N#N,O=C([O-])[O-].[K+].[K+],test
US03991076,C1=C(N2CCCC2)CCSC1.O.O=C(CBr)c1ccc(Br)cc1>>O=C(CC1CSCCC1=O)c1ccc(Br)cc1,,O,,CN(C)C=O,,test
US04263037,CC(=O)Cl.CC1(C)c2cc(Br)ccc2OC1O>>CC(=O)OC1Oc2ccc(Br)cc2C1(C)C,,CCOCC,,CCN(CC)CC,,test
US20130158049A1,Cc1cnccc1C#Cc1cc(Br)cnc1N>>Cc1cnccc1-c1cc2cc(Br)cnc2[nH]1,,CN1CCCC1=O,O,CC(C)(C)[O-].[K+],,test
US20150307493A1,CC1(C)Oc2c(Br)cc(S(C)(=O)=O)cc2NC1=O.CI>>CN1C(=O)C(C)(C)Oc2c(Br)cc(S(C)(=O)=O)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20070027155A1,C[C@@H]1CNCCN1.Clc1ncc(Cl)c(Cl)n1>>C[C@@H]1CN(c2nc(Cl)ncc2Cl)CCN1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20160159789A1,Clc1ncnc2[nH]ccc12.Nc1cc2cn[nH]c2cn1>>c1nc(Nc2cc3cn[nH]c3cn2)c2cc[nH]c2n1,,CCO,,Cl,,test
US20120053173A1,CC(=O)c1cc([N+](=O)[O-])ccc1O.O=C(CBr)C1CCCCC1>>Cc1c(C(=O)C2CCCCC2)oc2ccc([N+](=O)[O-])cc12,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20120108587A1,C1COCCN1.Fc1ccc(Nc2ccc3c(Cl)nncc3n2)c(F)c1>>Fc1ccc(Nc2ccc3c(N4CCOCC4)nncc3n2)c(F)c1,,CN1CCCC1=O,O,,,test
US20120225904A1,Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)nc2c1>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccn2c(=O)n(C3CCNCC3)nc2c1,,C1CCOC1,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20120101136A1,CN(C)CCCO.Cc1cc(O)ccc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1>>Cc1cc(OCCCN(C)C)ccc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070185161A1,C1COCCN1.CS(=O)(=O)Nc1cccc2c(C3(CCCI)CCc4cc(F)ccc43)c[nH]c12>>CS(=O)(=O)Nc1cccc2c(C3(CCCN4CCOCC4)CCc4cc(F)ccc43)c[nH]c12,,C1CCOC1,,,,test
US20080032973A1,COc1ccc(CN2Cc3cc(Cl)ccc3N(Cc3ccccc3)C2)cc1.O=C(O)C(F)(F)F>>O=C1NCc2cc(Cl)ccc2N1Cc1ccccc1,,ClCCl,,,,test
US20030004157A1,CC(C)(C(=O)Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.CNc1cnc(N2CCSCC2)cc1-c1ccccc1C>>Cc1ccccc1-c1cc(N2CCSCC2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20160060255A1,C[Sn](C)(C)Cl.c1ccc(COC2(c3nccs3)CCC2)cc1>>C[Sn](C)(C)c1cnc(C2(OCc3ccccc3)CCC2)s1,,CCOCC,,,,test
US20110136778A1,Cc1cc(C)n(C(=O)CC#N)n1.c1nc(N2CCCC3(CCCN3)C2)c2cc[nH]c2n1>>N#CCC(=O)N1CCCC12CCCN(c1ncnc3[nH]ccc13)C2,,C1COCCO1,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20030130204A1,COC(=O)CC[C@H]1COC(C)(C)N1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1[C@@H](CCC(=O)O)COC1(C)C,,CO,O,[Na+].[OH-],,test
US20090008606A1,Brc1ccc(Br)c2ccccc12.OB(O)c1ccccc1>>Brc1ccc(-c2ccccc2)c2ccccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20050032871A1,Cc1[nH]c(C=O)c(CCC(=O)O)c1S(C)(=O)=O.O=C1Cc2ccc(-c3ccc(F)cc3)cc2N1>>Cc1[nH]c(/C=C2\C(=O)Nc3cc(-c4ccc(F)cc4)ccc32)c(CCC(=O)O)c1S(C)(=O)=O,,CCO,,C1CCNCC1,,test
US20020028841A1,CC(C)O.Cc1nc[nH]c1C=O.NC(=O)c1cc2c(s1)NC(=O)C2>>COc1cc[nH]c1/C=C1\C(=O)Nc2sc(C(N)=O)cc21,,CC(C)O,,C1CCNCC1,,test
US20040010007A1,CCCc1nc2c(Oc3ccccc3)nc(C)c(C)c2n1CCCCCCl.Sc1ccc(Cl)cc1>>CCCc1nc2c(Oc3ccccc3)nc(C)c(C)c2n1CCCCCSc1ccc(Cl)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US05306728,BrCc1ccsc1.OCCO>>OCCOCc1ccsc1,,C1CCOC1,,CN(C)C=O,[H-].[Na+],test
US04408073,C=CC(=O)NCC(C)(C)CN(C)C.CCl>>C=CC(=O)NCC(C)(C)C[N+](C)(C)C.[Cl-],,O,,,,test
US04946843,CN1CCN(Cc2nc3cccnc3n2CCOCc2ccccc2)CC1>>CN1CCN(Cc2nc3cccnc3n2CCO)CC1,[Pd],CO,,[H][H],,test
US20150094328A1,Cn1cc(CCl)cn1.O=C(N[C@H]1CCCC[C@@H]1O)c1c[nH]c2c(Cl)ccnc12>>Cn1cc(Cn2cc(C(=O)N[C@H]3CCCC[C@@H]3O)c3nccc(Cl)c32)cn1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20060084663A1,CCN(CC)CC.Cc1cc(C(=O)O)ccc1CCC(=O)O.Cc1oc(-c2ccc(C(F)(F)F)cc2)nc1CN>>CCOC(=O)CCc1ccc(C(=O)NCc2nc(-c3ccc(C(F)(F)F)cc3)oc2C)cc1C,CN(C)c1ccncc1,ClC(Cl)Cl,ClCCl,CCN=C=NCCCN(C)C,,test
US20130065861A1,CCCCCCCCCCCCOC[C@H](CSC[C@H](N)C(=O)NCCOCCOCCOCCP(=O)(OCC)OCC)NC(=O)CCCCCCCCCCC>>CCCCCCCCCCCCOC[C@H](CSC[C@H](N)C(=O)NCCOCCOCCOCCP(=O)(O)O)NC(=O)CCCCCCCCCCC,,ClCCl,,C[Si](C)(C)Br,,test
US20090105259A1,CC(C)C[C@H](NC(=O)c1cccc2c1CCNC2)C(=O)NCCCCNS(=O)(=O)c1ccc(F)cc1Cl.ClCc1ccccc1>>CC(C)C[C@H](NC(=O)c1cccc2c1CCN(Cc1ccccc1)C2)C(=O)NCCCCNS(=O)(=O)c1ccc(F)cc1Cl,,ClCCl,,CCN(CC)CC,,test
US20140275070A1,CC(C)(C)[Si](C)(C)OC[C@H](CCl)O[Si](C)(C)C(C)(C)C.Cc1ccc2[nH]c(C#N)cc2c1>>Cc1ccc2c(c1)cc(C#N)n2C[C@@H](CO[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C,,CN(C)C=O,O,[H-].[Na+],,test
US20110028447A1,CC(C)(C)[C@@H](C#N)NC(=O)OCc1ccccc1.[N-]=[N+]=[N-].[NH4+]>>CC(C)(C)[C@H](NC(=O)OCc1ccccc1)c1nn[nH]n1,,CN(C)C=O,,[Cl-].[Na+],,test
US20070072925A1,C#Cc1cccc(O)c1.FC(F)Oc1ccc(I)cc1>>Oc1cccc(C#Cc2ccc(OC(F)F)cc2)c1,I[Cu]I,CN(C)C=O,,CCN(CC)CC,CCOC(C)=O,test
US05684161,C#CC(=O)OCC.CN(C=O)CC(=O)O>>CCOC(=O)c1ccn(C)c1,,CC(=O)OC(C)=O,,,,test
US20010027196A1,CS(=O)c1nc(N)nc(-n2cccn2)c1C#N.Cc1ccccc1CN>>Cc1ccccc1CNc1nc(N)nc(-n2cccn2)c1C#N,,COCCOC,,C1CCC2=NCCCN2CC1,,test
US20060014797A1,CNC.Cc1ccc2cc(CCOS(C)(=O)=O)sc2c1>>Cc1ccc2cc(CCN(C)C)sc2c1,,CO,,,,test
US20120264748A1,CC1CCC2(CCNCC2)C(=O)N1c1cccc2ccccc12.Clc1cnc2ccccc2n1>>O=C1N(Cc2cccc3ccccc23)CCCC12CCN(c1cnc3ccccc3n1)CC2,,CCO,,CCN(CC)CC,Cl,test
US20090312381A1,CC(=O)O.CCN=C=NCCCN(C)C.CN(C)C=O.Cl.NCc1cccc(C(F)(F)F)c1.On1nnc2ccccc21>>O=C(Cn1cc(-c2ccc(Cl)cc2)n(C2CC2)c1=O)NCc1cccc(C(F)(F)F)c1,,O,,,,test
US20120157448A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1O[C@H]1CCN(C(=O)OCc3ccccc3)C[C@@H]12>>CC(C)(C)OC(=O)NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1O[C@H]1CCN(C(=O)OCc3ccccc3)C[C@@H]12,CO,ClCCl,,CC(C)O,,test
US05714148,Cc1cccc(N)c1.O=C(N[C@@](Cc1ccccc1)(CC(C(=O)[O-])N(CCCl)CCCl)C(=O)[O-])Oc1ccccc1>>Cc1cccc(C(C[C@](Cc2ccccc2)(NC(=O)Oc2ccccc2)C(=O)O)(C(N)=O)N(CCCl)CCCl)c1,,C1CCOC1,C1CCOC1,CC(C)COC(=O)Cl,CCN(CC)CC,test
US05962470,O=C1SC(Cc2ccc(O)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1.OCCn1ccc2cccnc21>>O=C1SC(Cc2ccc(OCCn3ccc4cccnc43)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1,,c1ccccc1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US04214094,CCOC(=O)C(C)(C)Br.Oc1ccc(CNc2ccc(Cl)cc2)cc1>>CCOC(=O)C(C)(C)Oc1ccc(CNc2ccc(Cl)cc2)cc1,,CC(=O)CC(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20120039849A1,COc1ncc(N2CCC3(CC2)OCCO3)nc1OC>>COc1ncc(N2CCC(=O)CC2)nc1OC,,Cl,,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US04107310,CC(C)c1nc2c(C(F)(F)F)cccc2c(O)c1C(=O)O.Nc1nccs1>>CC(C)c1nc2c(C(F)(F)F)cccc2c(O)c1C(=O)Nc1nccs1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20070129345A1,COC(=O)C1CCN(C(=O)OCc2ccccc2)CC1.ClCCBr>>COC(=O)C1(CCCl)CCN(C(=O)OCc2ccccc2)CC1,,C1CCOC1,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20080234255A1,CCCCN(CCC(=O)OC(C)(C)C)c1nc(Cl)ncc1[N+](=O)[O-]>>CCCCN(CCC(=O)OC(C)(C)C)c1nc(Cl)ncc1N,[Pd],CCOC(C)=O,,[H][H],,test
US20120035134A1,CCN(CC)CC1CN(CC[C@H](CSc2ccccc2)Nc2ccc(S(=O)(=O)NC(=O)c3ccc(N4CCC([C@@H](O[Si](C)(C)C(C)(C)C)c5ccccc5-c5ccc(Cl)cc5)CC4)cc3)cc2S(=O)(=O)C(F)(F)F)CCO1>>CCN(CC)CC1CN(CC[C@H](CSc2ccccc2)Nc2ccc(S(=O)(=O)NC(=O)c3ccc(N4CCC([C@@H](O)c5ccccc5-c5ccc(Cl)cc5)CC4)cc3)cc2S(=O)(=O)C(F)(F)F)CCO1,,C1COCCO1,ClCCl,CCN(CC)CC,Cl,test
US20150368260A1,Cc1nsc(N)c1C(=O)O.Nc1ccc(Cl)c(Cl)c1>>Cc1nsc(N)c1C(=O)Nc1ccc(Cl)c(Cl)c1,,C1CCOC1,O,CCN(CC)CC,O=S(Cl)Cl,test
US20120264737A1,Cc1cc(C2CCC2)c(C(=O)O)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1.O=C(Cl)C(=O)Cl>>Cc1cc(C2CCC2)c(C(=O)Cl)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1,CN(C)C=O,ClCCl,,,,test
US20140249129A1,CC1(C)CC(=O)C=C(Nc2cccc(C(F)(F)F)c2)C1.O=C=NC(Cl)c1ccc(Br)cc1>>CC1(C)CC(=O)C2=C(C1)N(c1cccc(C(F)(F)F)c1)C(=O)NC2c1ccc(Br)cc1,,ClCCl,,,,test
US04595687,O=C(OO)c1cccc(Cl)c1.Oc1ccc(SCC2COC(c3ccccc3)=N2)cc1>>O=S(CC1COC(c2ccccc2)=N1)c1ccc(O)cc1,,ClCCl,,,,test
US20140371203A1,C1CCN(CCOCC2CCNCC2)C1.Clc1ncnc2sc(Br)c(-c3ccccc3)c12>>Brc1sc2ncnc(N3CCC(COCCN4CCCC4)CC3)c2c1-c1ccccc1,,C1CCOC1,O,CCN(C(C)C)C(C)C,,test
US20150336979A1,CCOC(=O)CC[C@H]1CO[C@@H]2[C@@H](N)CO[C@H]12.O=C=NC1CCCCC1>>CCOC(=O)CC[C@H]1CO[C@@H]2[C@@H](NC(=O)NC3CCCCC3)CO[C@H]12,,ClCCl,,,,test
US05231102,CC(C)(C)OC(=O)N[C@@H]1C[C@H](C(=O)O)Nc2cc(Cl)cc(Cl)c21.Cl>>Cl.N[C@@H]1C[C@H](C(=O)O)Nc2cc(Cl)cc(Cl)c21,,CCOC(C)=O,,,,test
US05143831,CCOC(CCCl)OCC.CN(C)C=O>>CCOC(CCN)OCC,[Pd],CCO,,,,test
US20050137243A1,O=[N+]([O-])c1ccc2c(c1)c(Cl)nn2CCN1CCCC1>>Nc1ccc2c(c1)c(Cl)nn2CCN1CCCC1,[Fe],CCO,,[Cl-].[NH4+],,test
US04038396,CC(=O)OC(C)=O.Nc1cccc(-c2nc3ncccc3o2)c1>>CC(=O)Nc1cccc(-c2nc3ncccc3o2)c1,,O,,c1ccncc1,,test
US20050096309A1,COC(=O)CN([C@H]1CCCN(C2CCN(C(C)C)CC2)C1=O)S(=O)(=O)c1ccc2cc(Cl)ccc2c1.N>>CC(C)N1CCC(N2CCC[C@H](N(CC(N)=O)S(=O)(=O)c3ccc4cc(Cl)ccc4c3)C2=O)CC1,,CO,,,,test
US20060160081A1,CC(N=[N+]=[N-])OCCO.CCOC(=O)CBr>>CCOC(=O)COCCOC(C)N=[N+]=[N-],,C1CCOC1,,[H-].[Na+],,test
US20020086901A1,CC(CCC(=O)O)C1CCCC1.[Li]C>>CC(=O)CCC(C)C1CCCC1,,CCOCC,,O,,test
US20100137587A1,CCOC(=O)c1cn(-c2ccccc2F)nn1>>O=C(O)c1cn(-c2ccccc2F)nn1,,CCO,O,,,test
US20050014767A1,Cc1nc2cc(-c3ccc(C=O)cn3)cc(C34CC5CC(CC(C5)C3)C4)c2o1.O=C1CSC(=O)N1>>Cc1nc2cc(-c3ccc(C=C4SC(=O)NC4=O)cn3)cc(C34CC5CC(CC(C5)C3)C4)c2o1,,Cc1ccccc1,,C1CCNCC1,CC(=O)O,test
US20120114739A1,C[Si](C)(C)c1cc2cc(Br)cnc2s1>>Brc1cnc2sccc2c1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20020169172A1,N.Nc1nc(Cl)cnc1-c1cc(Cl)cc(Cl)c1Cl>>Nc1cnc(-c2cc(Cl)cc(Cl)c2Cl)c(N)n1,,CCO,,,,test
US20090209536A1,ClCc1nc(Nc2ccccc2)c2ccccc2n1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCc1nc(Nc2ccccc2)c2ccccc2n1,,CS(C)=O,,O,,test
US20060178373A1,CC(C)N.COc1cc(OC)cc(-c2cc(=O)c3ccc(OCC4CO4)cc3o2)c1>>COc1cc(OC)cc(-c2cc(=O)c3ccc(OCC(O)CNC(C)C)cc3o2)c1,,CO,,,,test
US20160102083A1,CCC(c1scc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCN(C(=O)OC(C)(C)C)CC1>>CCC(c1scc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCNCC1,,CO,,C1COCCO1,Cl,test
US20050228004A1,COc1ccc(-c2nc3c(NC4CCCC4)cccn3c2-c2ccnc(NC3CCCC3)n2)cc1>>Oc1ccc(-c2nc3c(NC4CCCC4)cccn3c2-c2ccnc(NC3CCCC3)n2)cc1,,ClCCl,,BrB(Br)Br,,test
US05395846,BrCc1ccc(-c2nc3ccccc3o2)cc1.OC12CC3CC(C1)CC(NC(c1ccccc1)(c1ccccc1)c1ccccc1)(C3)C2>>c1ccc(C(NC23CC4CC(C2)CC(OCc2ccc(-c5nc6ccccc6o5)cc2)(C4)C3)(c2ccccc2)c2ccccc2)cc1,,C1CCOC1,,CO,,test
US05608056,CC(C)(C)[Si](C)(C)O[C@@H]1C[C@@H](C=O)N(Cc2ccccc2)C1.Cn1cccn1>>Cn1nccc1C(O)[C@@H]1C[C@@H](O[Si](C)(C)C(C)(C)C)CN1Cc1ccccc1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20110312979A1,CC(=O)c1cc2ccccc2n1-c1cccc(F)c1>>CC(O)c1cc2ccccc2n1-c1cccc(F)c1,,CO,,[BH4-].[Na+],,test
US04879389,CS(=O)(=O)N1C[C@@H](P(=O)(c2ccccc2)c2ccccc2)C[C@H]1CO>>CS(=O)(=O)N1C[C@@H](P(=O)(C2CCCCC2)C2CCCCC2)C[C@H]1CO,,CO,,[H][H],,test
US20070105865A1,COCc1nc(Cl)c2ccc(-c3ncccc3C(F)(F)F)nc2n1.Nc1ccc2c(c1)NCCC2>>COCc1nc(Nc2ccc3c(c2)NCCC3)c2ccc(-c3ncccc3C(F)(F)F)nc2n1,,CC#N,,,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2cc(OC)ccc23)cc1.COc1ccc(N)cc1OC>>COc1ccc2c(c1)nc(Nc1ccc(OC)c(OC)c1)c1n[nH]cc12,C1COCCO1,CO,,Cl,,test
US20140275172A1,CCOC(=O)c1cc(Cl)cc([N+](=O)[O-])c1SCc1ccccc1>>CCOC(=O)c1cc(Cl)cc(N)c1SCc1ccccc1,[Fe],CCO,,[Cl-].[NH4+],,test
US20030195362A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C[C@H](O)[C@@H](N)Cc1ccccc1.O=C(OCc1cncs1)Oc1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1cncs1,,CN(C)C=O,,,,test
US20060014739A1,CC1CCCCN1.N#Cc1ccc(F)c2ccccc12>>CC1CCCCN1c1ccc(C#N)c2ccccc12,,c1ccncc1,,C1CCC2=NCCCN2CC1,,test
US20010047001A1,Cc1cccc(C)c1NC(=O)CN1CCN(CC(O)COC2Cc3ccccc3C2)CC1.OCc1ccc2ccccc2c1>>Cc1cccc(C)c1NC(=O)CN1CCN(CC(O)COCc2ccc3ccccc3c2)CC1,,CC(C)O,,,,test
US20050032871A1,Cc1[nH]c(C=O)c(CCC(=O)O)c1S(=O)(=O)c1ccc(Cl)cc1.O=C1Cc2ccccc2N1>>Cc1[nH]c(/C=C2\C(=O)Nc3ccccc32)c(CCC(=O)O)c1S(=O)(=O)c1ccc(Cl)cc1,,CCO,,C1CCNCC1,,test
US20140005182A1,C1CCOC1.CN(C)[C@@H]1CCCC[C@H]1N.COc1ccc(Cc2cc3c(=O)[nH]cnc3c3ccccc23)cc1.Ic1cccnc1.O=c1[nH]cnc2c1cc(Cc1ccc(Cl)nc1)c1ccccc12>>COc1ccc(Cc2cc3c(=O)[nH]cnc3c3ccccc23)cc1.COc1ccc(Cc2cc3c(=O)n(-c4cccnc4)cnc3c3ccccc23)cc1,[Cu]I,C1CCOC1,CS(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040192731A1,CC(C)N.Cc1cccc(S(=O)(=O)Cl)c1[N+](=O)[O-]>>Cc1cccc(S(=O)(=O)NC(C)C)c1[N+](=O)[O-],,ClCCl,,O,,test
US20040110807A1,CCO[C@H](C(=O)OC)[C@H](O)c1ccc(OCc2ccccc2)cc1Cl>>CCO[C@@H](Cc1ccc(OCc2ccccc2)cc1Cl)C(=O)OC,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20070124152A1,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCO)c1=O.CN>>CNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCO)c1=O,,CCO,,,,test
US05863947,NC(C(=O)O)c1cc(O)cc(O)c1.O=[N+]([O-])O>>NC(C(=O)O)c1cc(O)cc(O)c1[N+](=O)[O-],,O,,[Na+].[OH-],,test
US20050070441A1,CCC(C)N.Cc1cc(Oc2ncc(C(F)(F)F)cc2Cl)n[nH]1.O=C(Cl)OC(Cl)(Cl)Cl>>CCC(C)NC(=O)n1nc(Oc2ncc(C(F)(F)F)cc2Cl)cc1C,,ClC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US20050159423A1,CSc1nccc(Cl)n1.N>>CSc1nccc(N)n1,,CO,,,,test
US20080051418A1,CC(C)Oc1cc(C=O)n(Cc2ccccc2)n1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)/C=C/c1cc(OC(C)C)nn1Cc1ccccc1,,C1CCOC1,CN(C)C=O,O,[H-].[Na+],test
US20010014677A1,CCCC[Sn](CCCC)(CCCC)COC.COc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1ccc2c(c1)OCO2)c1cn(C)c2cc(Br)ccc12>>COCc1ccc2c(C(C(=O)NS(=O)(=O)c3ccc(C)cc3OC)c3ccc4c(c3)OCO4)cn(C)c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20070203120A1,Cc1ccc(S(=O)(=O)OCCc2ccc3[nH]cc(S(=O)(=O)c4ccccc4)c3c2)cc1.c1ccc(CN2CCNCC2)cc1>>O=S(=O)(c1ccccc1)c1c[nH]c2ccc(CCN3CCN(Cc4ccccc4)CC3)cc12,,C1CCOC1,,,,test
US20130150341A1,COC(=O)CBr.Fc1ccc(-c2n[nH]c(-c3ccc(F)cc3)n2)cc1>>COC(=O)Cn1nc(-c2ccc(F)cc2)nc1-c1ccc(F)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150239862A1,CC(C)=O.OCc1cc(Br)ccc1O>>CC1(C)OCc2cc(Br)ccc2O1,,C1CCOC1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100130489A1,CCOC(=O)c1cc(-c2cnc3c(NCCCO)nc4cc(C(F)(F)F)ccc4n23)[nH]n1>>O=C(O)c1cc(-c2cnc3c(NCCCO)nc4cc(C(F)(F)F)ccc4n23)[nH]n1,,C1CCOC1,O,[Li+].[OH-],,test
US20010014691A1,CN.Cc1ncccc1OCCCCl>>CNCCCOc1cccnc1C,,CO,,,,test
US20060293307A1,O=C(CF)NC[C@H]1CN(c2ccc(N3CCNCC3)c(F)c2)C(=O)O1.O=[N+]([O-])c1ccc(Br)s1>>O=C(CF)NC[C@H]1CN(c2ccc(N3CCN(c4ccc([N+](=O)[O-])s4)CC3)c(F)c2)C(=O)O1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20090221583A1,O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)c1cnc(Cl)cn1.OB(O)c1ccccc1>>O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)c1cnc(-c2ccccc2)cn1,Cl[Pd]Cl,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20140371220A1,Cc1cn(-c2ccc(Cl)nn2)cn1.Fc1ccc2c(c1)N(C1CCNCC1)CC2>>Cc1cn(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20060074083A1,CC(N)=O.Cn1c(C(=O)c2ccc(F)cc2)cc2cc(Br)ccc21>>CC(=O)Nc1ccc2c(c1)cc(C(=O)c1ccc(F)cc1)n2C,,C1COCCO1,O,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20050096310A1,C=Cc1cncc2cccc([N+](=O)[O-])c12.O=C(OO)c1cccc(Cl)c1>>C=Cc1c[n+]([O-])cc2cccc([N+](=O)[O-])c12,,ClCCl,,O=C([O-])O.[Na+],,test
US20060135561A1,COc1cc(N)cc(OC)c1OC.Cc1ccccc1C1C[N+](C)(Cc2ccccc2)CCC1=O>>COc1cc(N2CCC(=O)C(c3ccccc3C)C2)cc(OC)c1OC,,CCO,O,[I-].[K+],,test
US05252575,CC(C)OCOCCCO.O=C1c2ccccc2C(=O)N1O>>CC(C)OCOCCCON1C(=O)c2ccccc2C1=O,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06391518B1,CC(C)(C)OC(=O)C1C2C=CC(C2)C1C(=O)OC(C)(C)C.O=C(O)C1C2C=CC(C2)C1C(=O)O.O=C(OCCO)C1CC2C=CC1C2.O=C1C=CC(=O)O1>>CC(C)(C)OC(=O)C1C2C=CC(C2)C1C(=O)OC(C)(C)C.O=C(O)C1C2C=CC(C2)C1C(=O)O.O=C(OCCO)C1CC2C=CC1C2.O=C1C=CC(=O)O1,,C1CCOC1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20160083400A1,COC(=O)c1ncnc(C(C)C)c1N>>CC(C)c1ncnc(C(=O)O)c1N,,C1CCOC1,O,[Li+].[OH-],,test
US20080214580A1,COC(=O)O[C@@H]1CC[C@@H](n2c(=O)[nH]c3c(Cl)nc(N)nc32)CC1>>Nc1nc(Cl)c2[nH]c(=O)n([C@@H]3CC[C@@H](O)CC3)c2n1,,[K+],[OH-],Cl,,test
US20110190540A1,CC1(C)CCCC(C)(C)N1[O].O=c1n(Cl)c(=O)n(Cl)c(=O)n1Cl.OCCCCCc1ccccc1>>CC(C)(C)NN=CCCCCc1ccccc1,,ClCCl,,,,test
US20080318947A1,CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)nc(OCCCCNC(=O)OC(C)(C)C)cc21>>CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)nc(OCCCCN)cc21,,CO,,Cl,,test
US06713471B1,CCOC(=O)C=C1Cc2ccccc2C1>>CCOC(=O)CC1Cc2ccccc2C1,[Pd],CCOC(C)=O,,,,test
US04069221,N#CC1(c2ccccc2)CCNCC1.c1ccc2c(OCC3CO3)cccc2c1>>N#CC1(c2ccccc2)CCN(CC(O)COc2cccc3ccccc23)CC1,,CCO,,,,test
US20130225529A1,CCOP(=O)(Cl)OCC.COc1ccc2c(c1)c(CC(=O)Oc1ccc(CCO)cc1)c(C)n2C(=O)c1ccc(Cl)cc1>>CCOP(=O)(OCC)OCCc1ccc(OC(=O)Cc2c(C)n(C(=O)c3ccc(Cl)cc3)c3ccc(OC)cc23)cc1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160108040A1,CC(C)(C)c1cc(N)n(-c2cnn(CCO)c2)n1.O=C(Cl)OCC(Cl)(Cl)Cl>>CC(C)(C)c1cc(NC(=O)OCC(Cl)(Cl)Cl)n(-c2cnn(CCO)c2)n1,,CCOC(C)=O,,[Na+].[OH-],,test
US20060106048A1,CCOC(=O)c1ccc(C2=NC(C)(C)Cc3cc(OCC)c4c(c32)CC(C)(C)O4)cc1N(Cc1ccccc1)C(C)=O>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)O)c(N(Cc3ccccc3)C(C)=O)c1)=NC(C)(C)C2,,CO,,[Na+].[OH-],,test
US20150141428A1,C[Si](C)(C)CCOCCl.O=Cc1c[nH]c2ncccc12>>C[Si](C)(C)CCOCn1cc(C=O)c2cccnc21,,CN(C)C=O,,[H-].[Na+],,test
US20050038035A1,CC(=O)Nc1cccc(/C=C/C(=O)c2ccc(NC(=O)c3ccc(C)cc3-c3ccc(C)cc3)cc2)n1>>CC(=O)Nc1cccc(CCC(=O)c2ccc(NC(=O)c3ccc(C)cc3-c3ccc(C)cc3)cc2)n1,[Pd],CO,,[H][H],,test
US20140163233A1,COB(OC)OC.c1ccc(-c2ccc3sc4ccccc4c3c2)cc1>>OB(O)c1cccc2c1sc1ccc(-c3ccccc3)cc12,,C1CCOC1,,[Li]CCCC,,test
US20080269210A1,Clc1nc(N2CCOCC2)c2cc(Cl)sc2n1.O=C1COC1>>OC1(c2cc3c(N4CCOCC4)nc(Cl)nc3s2)COC1,,C1CCOC1,,[Li]CCCC,,test
US20130072523A1,COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(C#C[Si](C)(C)C)c[nH]1)C(C)C>>C#Cc1c[nH]c([C@@H]2CCCN2C(=O)[C@@H](NC(=O)OC)C(C)C)n1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120283222A1,CCOP(=O)(Cl)OCC.CCS(=O)(=O)OC(C)C>>CCOP(=O)(OCC)C(C)S(=O)(=O)OC(C)C,,C1CCOC1,,Cl,[Li]CCCC,test
US06090825,COCc1nc(C2CCN(C(C)=O)CC2)oc1-c1ccc(F)cc1>>COCc1nc(C2CCNCC2)oc1-c1ccc(F)cc1,,CCO,O,[Na+].[OH-],,test
US20120289474A1,CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3cc(Br)sc3c2=O)CC1.COCc1noc(CCl)n1>>COCc1noc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(Br)cc32)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130109665A1,CC1CCC(C(C)C)C(OC(=O)Cl)C1.NC(c1ccccn1)C(F)(F)F>>CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)NC(c1ccccn1)C(F)(F)F,,C1CCOC1,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20150175562A1,COC(=O)c1nc(CC2CCCCC2)c(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)o1>>CC(C)(C)c1cc(-c2oc(C(=O)O)nc2CC2CCCCC2)cc(C(C)(C)C)c1,,C1CCOC1,O,[Li]O,,test
US20110178140A1,CCOC(=O)C(=O)Cl.c1c[nH]cn1>>CCOC(=O)C(=O)n1ccnc1,,C1CCOC1,,,,test
US20120058988A1,C1COCCN1.O=Cc1ccc(Br)cc1Cl>>Clc1cc(Br)ccc1CN1CCOCC1,,C1CCOC1,CCOC(C)=O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20120252780A1,CC(C)(C)OC(=O)N1CCC(=O)c2ccc(-c3cccc(C(F)(F)F)c3)nc21>>O=C1CCNc2nc(-c3cccc(C(F)(F)F)c3)ccc21,,CO,Cl,,,test
US20100081846A1,C[Si](C)(C)Cl.c1ccc(Cc2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1>>C[Si](C)(C)C(c1ccccc1)c1ccc(N(c2ccccc2)c2ccccc2)cc1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20130079328A1,Cc1cc(-c2cnc(CN)c(C)c2)ccn1.O=C(O)c1ccc(-c2cnccn2)cn1>>Cc1cc(-c2cnc(CNC(=O)c3ccc(-c4cnccn4)cn3)c(C)c2)ccn1,,CN(C)C=O,CS(C)=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120245137A1,CC(C)(C)OC(=O)NCC1CCC(OS(C)(=O)=O)CC1.CS(=O)(=O)c1nc(C(F)(F)F)ccc1C(=O)O>>CC(C)(C)OC(=O)NCC1CCC(Sc2cccc(C(F)(F)F)c2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060100249A1,CC(=O)OC(C)=O.N#Cc1ccccc1-c1cc(-c2ccccn2)cn(-c2cccc(CO)c2)c1=O>>CC(=O)OCc1cccc(-n2cc(-c3ccccn3)cc(-c3ccccc3C#N)c2=O)c1,,c1ccncc1,,,,test
US20040186060A1,COC(=O)C(CCSC)N=Cc1ccc(Cl)cc1.Cl.N#Cc1cccc(CBr)c1>>COC(=O)C(N)(CCSC)Cc1cccc(C#N)c1.Cl,,C1CCOC1,,[H-].[Na+],,test
US04886802,CCOC(=O)CC1NCCN(CCc2c[nH]c3cc(OC)ccc23)C1=O.O=C(Cl)c1ccccc1>>CCOC(=O)CC1C(=O)N(CCc2c[nH]c3cc(OC)ccc23)CCN1C(=O)c1ccccc1,,CCN(CC)CC,,,,test
US20030008849A1,CC#CCOc1ccc(S(=O)(=O)N2CCNCC2C(=O)OCC)cc1.CC(=O)Cl>>CC#CCOc1ccc(S(=O)(=O)N2CCN(C(C)=O)CC2C(=O)OCC)cc1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20060211734A1,CN1CCC(Oc2cccc(N)c2F)CC1.O=C(Cl)c1ccc(F)cc1F>>CN1CCC(Oc2cccc(NC(=O)c3ccc(F)cc3F)c2F)CC1.Cl,,C1COCCO1,,,,test
US20100081644A1,O=C(O)CC1CCOCC1>>OCCC1CCOCC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120010228A1,Br.COC(=O)[C@@H](N)c1ccccc1>>COC(=O)[C@H](Br)c1ccccc1,,O,,O=N[O-].[Na+],,test
US20080207654A1,CCCC(=N)N.COCC(=O)CC(=O)OC>>CCCc1nc(COC)cc(=O)[nH]1,,CCOC(C)=O,CO,Cl,C[O-].[Na+],test
US20100267699A1,Cn1nccc1CCOc1ccc(C2CCN(C3=Nn4c(nnc4C(F)(F)F)CC3)CC2)cc1.Oc1ccc(N2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1>>Cn1nccc1CCOc1ccc(N2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05334748,CO/C=C(/C(=O)OC)c1ccccc1Oc1cccc(CO)c1.O=[Cr](=O)(O)O>>CO/C=C(/C(=O)OC)c1ccccc1Oc1cccc(C(=O)O)c1,,CC(C)=O,,O,,test
US20080039636A1,Cc1cc(=O)oc2cc(O)ccc12>>CC1CC(=O)Oc2cc(O)ccc21,[Pd],CC(=O)O,,,,test
US20130267493A1,COC(=O)c1c[nH]c2cc(Cl)c(-c3ccc(C4CCN4C(C)=O)cc3)cc12>>CC(=O)N1CCC1c1ccc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)cc1,,CO,,[Na+].[OH-],,test
US20100190777A1,CC(C)Nc1ccc(N)cn1.CCCS(=O)(=O)Nc1ccc(Cl)c(C(=O)Cl)c1F>>CCCS(=O)(=O)Nc1ccc(Cl)c(C(=O)Nc2ccc(NC(C)C)nc2)c1F,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US04990495,CC(C)COC1CCC=CCCC=CCCC1O>>CC(C)COC1CCC=CCCC=CCCC1=O,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US06124283,CN1CCN(c2cccc3c2C[C@H](N)CC3)CC1.O=C(O)CCCc1ccccc1>>CN1CCN(c2cccc3c2C[C@H](NC(=O)CCCc2ccccc2)CC3)CC1,,ClCCl,O=S(Cl)Cl,CCN(CC)CC,,test
US20120264735A1,Cn1cc(-n2ccc(=O)c(Cc3cccc(-c4ncc(OCc5ccccc5)cn4)c3)n2)cn1>>Cn1cc(-n2ccc(=O)c(Cc3cccc(-c4ncc(O)cn4)c3)n2)cn1,[Pd],CCO,ClCCl,,,test
US20090247746A1,Nc1cccc2c3c([nH]c12)C(=O)CCC3.O=S(=O)(Cl)c1cccs1>>O=C1CCCc2c1[nH]c1c(NS(=O)(=O)c3cccs3)cccc21,,c1ccncc1,,,,test
US20140187553A1,CC(C)(C)OC(=O)n1cc(-c2cccc(N3CCOCC3)n2)c2cc(-c3nnc(N)s3)ccc21>>Nc1nnc(-c2ccc3[nH]cc(-c4cccc(N5CCOCC5)n4)c3c2)s1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20010056179A1,COc1cccc2c1CCC(N)(C(=O)O)C2.O=C(OCC1c2ccccc2-c2ccccc21)ON1C(=O)CCC1=O>>COc1cccc2c1CCC(N)(C(=O)O)C2C(=O)OCC1c2ccccc2-c2ccccc21,,CC#N,O,CCN(CC)CC,,test
US20130040947A1,CN(C)c1ccc(-c2cc(=O)c3ccc(N)c([N+](=O)[O-])c3o2)cc1.Cl>>CN(C)c1ccc(-c2cc(=O)c3ccc(N)c(N)c3o2)cc1.Cl,[Pd],CO,,[H][H],,test
US05998433,O=C(OC(=O)C(F)(F)F)C(F)(F)F.c1cc2c(o1)CNCC2>>O=C(N1CCc2ccoc2C1)C(F)(F)F,,ClCCl,,Cl,c1ccncc1,test
US05834499,c1ccc(CN2CCC(c3nc4c(s3)Cc3ccccc3-4)C2)cc1>>c1ccc2c(c1)Cc1sc(C3CCNC3)nc1-2,,CC(Cl)Cl,,CC(Cl)OC(=O)Cl,,test
US20120208827A1,O=C(C1CC1)N1CC[C@@H](CNc2ccc(F)cc2[N+](=O)[O-])C1>>Nc1cc(F)ccc1NC[C@@H]1CCN(C(=O)C2CC2)C1,[Pd],CCO,,,,test
US20100004299A1,CCOC(=O)c1sc2nc(-c3ccc(F)cc3)cn2c1C>>Cc1c(C(=O)O)sc2nc(-c3ccc(F)cc3)cn12,,CCO,O,[Li+].[OH-],,test
US04628057,O=C(O)C1Cc2c([nH]c3ccccc23)CN1.O=[N+]([O-])c1ccc(CBr)cc1.S=C=S>>O=C(O)C1Cc2c([nH]c3ccccc23)CN1C(=S)SCc1ccc([N+](=O)[O-])cc1,,CS(C)=O,,[Na+].[OH-],,test
US20150150893A1,C=C1CC[C@@H]2[C@](C)(CO)[C@H](O)CC[C@@]2(C)[C@@H]1C/C=C1/C(=O)OC[C@H]1O.CCOCC1OC(Oc2ccc(C=O)cc2)C(OCC)C(OCC)C1OCC>>C=C1CCC2C3(C)COC(c4ccc(OC5OC(CO)C(O)C(O)C5O)cc4)OC3CCC2(C)C1C/C=C1/C(=O)OCC1O,,Cc1ccccc1,,,,test
US20110230452A1,C[Si](C)(C)C#Cc1ccc(S(=O)(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)O)s1>>C#Cc1ccc(S(=O)(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)O)s1,,CO,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20060106012A1,O=[N+]([O-])c1ccc(S(=O)(=O)c2ccccc2)cc1O>>Nc1ccc(S(=O)(=O)c2ccccc2)cc1O,[Pd],CCO,,,,test
US20140031338A1,COC(=O)C(OC(C)(C)C)c1cc([N+](=O)[O-])c(F)cc1Cl.N>>COC(=O)C(OC(C)(C)C)c1cc([N+](=O)[O-])c(N)cc1Cl,,CO,,,,test
US20090221669A1,CC(=O)OC(C)=O.COC(=O)c1ccc(NCCN(C)C)cc1>>COC(=O)c1ccc(N(CCN(C)C)C(C)=O)cc1,,ClCCl,,CCN(CC)CC,,test
US20100305111A1,C1CSCCN1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCSCC1,,CCOC(C)=O,ClCCl,CCN(CC)CC,O,test
US20080214544A1,BrCc1ccccc1.CSc1ncc(Br)c(=O)[nH]1>>CSc1ncc(Br)c(=O)n1Cc1ccccc1,,C1CCOC1,,,,test
US20050137226A1,Cl.Oc1ccc(Oc2ccc(OC3CN4CCC3CC4)cc2)cc1>>Cl.Oc1ccc(Oc2ccc(OC3CN4CCC3CC4)cc2)cc1,,CCOC(C)=O,,C1COCCO1,,test
US05753669,CCOC(=O)C12C=CC(C1)C1C(=O)N(Cc3ccccc3)C(=O)C12>>O=C1C2C3C=CC(C(=O)O)(C3)C2C(=O)N1Cc1ccccc1,,CO,,[Na+].[OH-],,test
US20080038242A1,CC(=O)OCCCCBr.N#Cc1cccc(S)c1>>CC(=O)OCCCCSc1cccc(C#N)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20160016910A1,CC1(C)CO1.COc1cc(C(=O)NCc2ccccc2F)ccc1Br>>COc1cc(C(=O)N(Cc2ccccc2F)CC(C)(C)O)ccc1Br,,CN(C)C=O,CO,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080193452A1,CC1(C)OC2C(COS(=O)(=O)O)OC(n3cnc4c(=O)[nH]c(N)nc43)C2O1>>Nc1nc2c(ncn2[C@@H]2O[C@H](COS(=O)(=O)O)[C@H](O)[C@@H]2O)c(=O)[nH]1,,O,,,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.COc1ccc(N)cc1O>>COc1ccc2nc(Nc3ccc(OC)c(O)c3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US20070179173A1,COC(=O)CBr.COc1ccc(CC2SC(=O)NC2=O)c2ccc(=O)n(C)c12>>COC(=O)CN1C(=O)SC(Cc2ccc(OC)c3c2ccc(=O)n3C)C1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130231327A1,COC(=O)c1ccc2c(c1)[C@H](NC(=O)c1ccccc1Cl)CCC2>>O=C(O)c1ccc2c(c1)[C@H](NC(=O)c1ccccc1Cl)CCC2,,CO,O,[Li+].[OH-],,test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCCCC1.O=C(O)c1cc2cc(O)ccc2[nH]1>>COc1cc2c(Oc3ccc4[nH]c(C(=O)O)cc4c3)ncnc2cc1OCCCN1CCCCC1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US05869516,CC1=NN(c2ccccc2)C(=O)C1.COC(OC)OC.COc1ccccc1N>>COc1ccccc1NC=C1C(=O)N(c2ccccc2)N=C1C,,CC(=O)O,,CO,,test
US20090076074A1,COc1ccc2c(Oc3ccc(CC(=O)Nc4cn(C)nc4C)c(OC)c3)ccnc2c1.O=C(O)/C=C\C(=O)O>>COc1ccc2c(Oc3ccc(CC(=O)Nc4cn(C)nc4C)c(OC)c3)ccnc2c1.O=C(O)/C=C\C(=O)O,,CCO,,COC(C)(C)C,,test
US20050137201A1,Nc1cccc(F)c1F.O=C(O)c1c[nH]c2ncc(Br)cc12>>O=C(Nc1cccc(F)c1F)c1c[nH]c2ncc(Br)cc12,,CN(C)C=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20090042896A1,CON(C)C(=O)C1CN(Cc2ccccc2)CC1c1ccc(Cl)c(Cl)c1>>O=CC1CN(Cc2ccccc2)CC1c1ccc(Cl)c(Cl)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20050113419A1,CCCc1c(OCCCNCC)ccc2c(C(F)(F)F)noc12.CN=C=O>>CCCc1c(OCCCN(CC)C(=O)NC)ccc2c(C(F)(F)F)noc12,,c1ccncc1,,,,test
US20020143044A1,N=C(N)c1ccccc1.O=C1CCCCC1O>>c1ccc(-c2nc3c([nH]2)CCCC3)cc1,,[NH4+],[OH-],Cl,,test
US05166385,C=CC(=O)OC.COP(OC)OC>>COC(=O)CCP(=O)(OC)OC,,CC(C)CO,,,,test
US20010051631A1,Cc1nc2cccc3c(=O)n(CCCCCNC(=O)OC(C)(C)C)c1n23.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1nc2cccc3c(=O)n(CCCCCNS(=O)(=O)C(F)(F)F)c1n23,,CC#N,CO,CCN(CC)CC,Cl,test
US20150197511A1,CN1CCC(Nc2cc(N)cc(C(F)(F)F)c2)CC1.O.O=C(Cl)Oc1ccccc1.c1ccncc1>>C=CC(=O)Nc1cc(NC(=O)Oc2ccccc2)cc(C(F)(F)F)c1,,ClCCl,,Cl,,test
US20100256163A1,CC(C)Br.CS(=O)(=O)c1cccc(C2CCNCC2)c1F>>CC(C)N1CCC(c2cccc(S(C)(=O)=O)c2F)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150011546A1,CCOC(=O)/C(=C/c1cncs1)N=[N+]=[N-]>>CCOC(=O)c1cc2scnc2[nH]1,,Cc1ccccc1,,,,test
US07138547B2,CCCCCCCCCCCCCCC[C@H]1OC(=O)N[C@H]1C>>CCCCCCCCCCCCCCC[C@@H](O)[C@H](C)NC,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060241173A1,COc1ccc(C(c2ccc(OC)c(OCc3ccccc3)c2)n2cncn2)cc1OCc1ccccc1>>COc1ccc(C(c2ccc(OC)c(O)c2)n2cncn2)cc1O,[Pd],C1CCOC1,CO,,,test
US20110118290A1,O=C(Cl)C(=O)Cl.O=C(O)c1cnn(-c2cccnc2)c1>>Cl.O=C(Cl)c1cnn(-c2cccnc2)c1,CN(C)C=O,ClCCl,,,,test
US04221814,CCC(=O)OC(=O)CC.CCCOC(=O)c1ccc(C(=O)Nc2cc(N)ccc2C(=O)O)cc1>>CCCOC(=O)c1ccc(C(=O)Nc2cc(NC(=O)CC)ccc2C(=O)O)cc1,,CCOC(C)=O,,,,test
US20150080393A1,CCOC(=O)[C@@H]1CC2(CCN(c3cc(OC(c4ccc(C#N)cc4-n4ccc(C)n4)C(F)(F)F)nc(N)n3)CC2)CN1C(=O)OCc1ccccc1.O.[Li]O>>Cc1ccn(-c2cc(C(=O)O)ccc2C(Oc2cc(N3CCC4(CC3)C[C@@H](C(=O)O)N(C(=O)OCc3ccccc3)C4)nc(N)n2)C(F)(F)F)n1,,O,,CO,Cl,test
US20130231327A1,CN[C@@H]1CCc2ccc(C(=O)OC)cc21.O=S(=O)(Cl)c1ccccc1Cl>>COC(=O)c1ccc2c(c1)[C@H](N(C)S(=O)(=O)c1ccccc1Cl)CC2,,ClCCl,,,,test
US20160024110A1,CCOC(=O)C(=O)c1cc(Oc2ccc(OC)cc2)c(Cl)cc1F.ClC(Cl)(Cl)Cl>>CCOC(=O)C(=C(Cl)Cl)c1cc(Oc2ccc(OC)cc2)c(Cl)cc1F,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20020042522A1,CCOC(=O)c1c(O)c([N+](=O)[O-])cn1C.COS(=O)(=O)OC>>CCOC(=O)c1c(OC)c([N+](=O)[O-])cn1C,,CC(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20040067955A1,CC(=O)c1cnc(-c2ccccc2)c(-c2ccc(=O)n(C(C)C)n2)c1.CNN.COOC(OOC)N(C)C>>CC(C)n1nc(-c2cc(-c3ccnn3C)cnc2-c2ccccc2)ccc1=O,,CCO,,,,test
US20150266824A1,CC(C)=C1C[C@@H]2COC(C)(C)N2C1=O>>CC(C)=C1C[C@H](CO)NC1=O,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20080194549A1,CN(C(=O)Cl)c1ccccc1.COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CNC2CC2)C(C)C)ccc1OC>>COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN(C(=O)N(C)c2ccccc2)C2CC2)C(C)C)ccc1OC,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,Cl,test
US20060199817A1,Clc1ccc2c(Cl)nncc2c1.FC(F)(F)c1nnc2n1CCNC2>>FC(F)(F)c1nnc2n1CCN(c1nncc3cc(Cl)ccc13)C2,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,Cl,test
US20080076924A1,CC(C)C1CN(c2nc3ccccc3o2)CCN1C(=NC#N)Nc1cccc2c1CCN(C(=O)OCc1ccccc1)C2>>CC(C)C1CN(c2nc3ccccc3o2)CCN1C(=NC#N)Nc1cccc2c1CCNC2,[Pd],CO,,,,test
US20040248947A1,COc1ccc(C=O)cn1.Nc1ccccc1C(=O)Nc1ccc(Br)c(C(F)(F)F)c1>>COc1ccc(CNc2ccccc2C(=O)Nc2ccc(Br)c(C(F)(F)F)c2)cn1,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US06410592B1,COC(=O)c1ccc2c(c1)CCC(C(C)NCc1ccccc1)=C2c1ccccc1>>CNCC1CCc2cc(C(=O)OC)ccc2C1c1ccccc1,[Pd],CO,,Cl,,test
US20140349996A1,C[C@@H]1C[C@H](O)c2ncnc(N3CCN(C(=O)[C@H](CNC(=O)OC(C)(C)C)c4ccc(Cl)c(F)c4)CC3)c21.ClCCl>>C[C@@H]1C[C@H](O)c2ncnc(N3CCN(C(=O)[C@H](CN)c4ccc(Cl)c(F)c4)CC3)c21.Cl.Cl,,C1COCCO1,ClCCl,,,test
US20080096940A1,CC(C)(C)O.Fc1cc(F)cc(Br)c1>>CC(C)(C)Oc1cc(F)cc(Br)c1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20100273806A1,CCOC(=O)CC1CCc2c1[nH]c1ccc(C(N)=NO)cc21.O=C(Cl)c1cc(Br)cc(OC(F)(F)F)c1>>CCOC(=O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cc(Br)cc(OC(F)(F)F)c4)n3)cc21,,C1COCCO1,O,,,test
US20100190804A1,COc1cccc(CCCNc2nc(Cl)ncc2Cl)c1.Nc1cccc(CO)c1>>COc1cccc(CCCNc2nc(Nc3cccc(CO)c3)ncc2Cl)c1,,C1COCCO1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04731458,C=S(C)(C)=O.CCC(CCCCC1CCC2CC(=O)C12)OC>>CCC(CCCCC1CCC2CC3(CO3)C12)OC,,CS(C)=O,,,,test
US20070142412A1,O=C(Cl)C(=O)Cl.O=C(O)c1ccc(Cl)cc1F>>O=C(Cl)c1ccccc1,,CN(C)C=O,,C1CCOC1,,test
US20110028447A1,CC(C)(C)[C@H](NC(=O)OCc1ccccc1)C(N)=O>>CC(C)(C)[C@@H](C#N)NC(=O)OCc1ccccc1,,ClCCl,c1ccncc1,O=P(Cl)(Cl)Cl,,test
US20090305298A1,CC#N.CCN(CC)C(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1.O=CO>>COC(=O)CCCCCN(C)C,,CC#N,,O,,test
US20060122171A1,COCCN1CCC(Nc2ncc3c(n2)C(C(=O)OC(C)(C)C)C(=O)N3)CC1>>COCCN1CCC(Nc2ncc3c(n2)CC(=O)N3)CC1,,O=C(O)C(F)(F)F,,,,test
US20140187553A1,COC(=O)c1ccc2[nH]cc([N+](=O)[O-])c2c1.NN>>NNC(=O)c1ccc2[nH]cc([N+](=O)[O-])c2c1,,CCO,,O,,test
US20050038035A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1CN(c2ccc([N+](=O)[O-])cc2)CCN1>>CC1CN(c2ccc([N+](=O)[O-])cc2)CCN1C(=O)OC(C)(C)C,CN(C)c1ccncc1,C1CCOC1,,,,test
US20100249085A1,COC(=O)C(=O)CC(C)=O.NNCc1ccccc1>>Cc1cc(C(=O)O)nn1Cc1ccccc1,,CC(=O)O,,Cl,Cl,test
US20120053170A1,C1CCOC1.CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ccc(CN)cn1.CC1(C)OB(c2ccc(N)c(F)c2)OC1(C)C.CN(C)c1ccncc1>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ccc(CNC(=O)Nc2ccc(B3OC(C)(C)C(C)(C)O3)cc2F)cn1,CN(C)c1ccncc1,,,CCN(CC)CC,,test
US20140005132A1,CC12CCC(=O)C=C1CCCC2=O>>CC12CCC(=O)C=C1CCCC2O,,CCO,,CC(=O)O,[BH4-].[Na+],test
US20020128232A1,COc1cc(N=C=O)cc(OC)c1.O=S1(=O)Nc2ccccc2N1>>COc1cc(NC(=O)N2c3ccccc3NS2(=O)=O)cc(OC)c1,,C1CCOC1,,CCN(CC)CC,,test
US20130143899A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ncc(F)c(I)c1F>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(F)c(I)c1F,CN(C)c1ccncc1,CN(C)C=O,O,,,test
US20080234301A1,CCOc1cc(-c2cnc[nH]c2=O)ccc1N.Cc1ccccc1N=C=O>>CCOc1cc(-c2cnc[nH]c2=O)ccc1NC(=O)Nc1ccccc1C,,ClCCl,,,,test
US04548914,Cc1ccc(C)cc1.Cc1ccccc1>>CCc1ccc(C)cc1,,,,O,,test
US20100240661A1,Cc1ncccc1-c1nn(CCCN2C[C@@H]3C[C@]3(c3ccc(C(F)(F)F)cc3)C2)c(=O)[nH]c1=O.Cl.ClCCl>>Cc1ncccc1-c1nn(CCCN2C[C@@H]3C[C@]3(c3ccc(C(F)(F)F)cc3)C2)c(=O)[nH]c1=O.Cl.Cl,,CO,ClCCl,,,test
US20130244958A1,COCCN(CCOC)C(=O)OC(C)Cl.COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F>>COCCN(CCOC)C(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120277229A1,CC1CCNCC1.Nc1cc(Cl)ccc1[N+](=O)[O-]>>CC1CCN(c2ccc([N+](=O)[O-])c(N)c2)CC1,,CN1CCCC1=O,,CCN(CC)CC,,test
US05665718,NC(=NO)c1ncn2c1[C@@H]1CCCN1C(=O)c1c(Br)cccc1-2.O=C(CCl)OC(=O)CCl>>O=C1c2c(Br)cccc2-n2cnc(-c3noc(CCl)n3)c2[C@@H]2CCCN12,,CN(C)C=O,,,,test
US20110009441A1,COC(C=CN(C)C)=C(C#N)C#N.[NH4+]>>COc1ccnc(N)c1C#N,,[NH4+],[OH-],,,test
US20150344485A1,O=Cc1ccc(Oc2ccc(C(F)(F)F)nc2)c(F)c1>>OCc1ccc(Oc2ccc(C(F)(F)F)nc2)c(F)c1,,CO,,[BH4-].[Na+],,test
US20050123533A1,BrBr.CCOP(=O)(OCC)c1cc(OC)c(OC)c(OC)c1>>CCOP(=O)(OCC)c1cc(OC)c(OC)c(OC)c1Br,,CC(=O)O,,O=C([O-])O.[Na+],,test
US04861792,COc1ccc(F)cc1.O=C1C=CC(=O)O1>>O=C(O)/C=C/C(=O)c1cc(F)ccc1O,,ClCCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US04379167,OC(CCl)CCCl.Oc1ccccc1Cl>>OC(CCCl)COc1ccccc1Cl,,CC(C)O,,O,[K+].[OH-],test
US05661146,Cl.O=C(NCCCCc1ccncc1)N1Cc2ccccc2Oc2ccc(Cl)cc21>>Cl.O=C(NCCCCc1ccncc1)N1Cc2ccccc2Oc2ccc(Cl)cc21,,CO,,,,test
US06211234B1,CCOC(=O)CCC(Cl)c1c(F)cccc1Cl.N#Cc1ccc(OCc2ccsc2)cc1O>>CCOC(=O)CCC(Oc1cc(OCc2ccsc2)ccc1C#N)c1c(F)cccc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20110053931A1,COc1cc2c(Oc3ccc(N)cc3F)ccnc2cc1OCCCN1CCOCC1.Fc1ncccc1-c1ccccn1>>COc1cc2c(Oc3ccc(Nc4ncccc4-c4ccccn4)cc3F)ccnc2cc1OCCCN1CCOCC1,,CN(C)C=O,,O,[H-].[Na+],test
US08129361B2,CC(C)(C)OC(=O)NC1(CCc2ccc(OCCCc3ccccc3)c(C(F)(F)F)c2)COC(C)(C)OC1.Cl>>Cl.NC(CO)(CO)CCc1ccc(OCCCc2ccccc2)c(C(F)(F)F)c1,,CCO,,,,test
US04620865,Cn1ncc(C(=O)O)c1Cl.NC1CC1>>Cn1ncc(C(=O)NC2CC2)c1Cl,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20060063757A1,C=O.COc1cc2c(cc1NS(=O)(=O)c1ccc(-c3ccc(Cl)cc3)s1)CCNCC2>>COc1cc2c(cc1NS(=O)(=O)c1ccc(-c3ccc(Cl)cc3)s1)CCN(C)CC2,,ClCCCl,,CCN(CC)CC,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100087489A1,CC(C)COC(=O)c1cccc(-n2ncc3cc(O[C@H](c4ccc5c(c4)OCOC5)[C@H](C)N)ccc32)c1.CC(F)(F)C(=O)O>>CC(C)COC(=O)c1cccc(-n2ncc3cc(O[C@H](c4ccc5c(c4)OCOC5)[C@H](C)NC(=O)C(C)(F)F)ccc32)c1,,ClCCl,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130178459A1,COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc(S(=O)(=O)NCCO)cc1.CS(=O)(=O)Cl>>CS(=O)(=O)OCCNS(=O)(=O)c1ccc(-c2c(O)ccc3[nH]c(=O)c4sccc4c23)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20140221435A1,CC(C)(C)OC(=O)c1ccc(NC(=O)c2ccc(C(F)(F)C(F)(F)F)cc2F)cc1.O=C(O)C(F)(F)F>>O=C(O)c1ccc(NC(=O)c2ccc(C(F)(F)C(F)(F)F)cc2Oc2ccc(F)cc2F)cc1,,ClCCl,,,,test
US20160002180A1,CC(C)C(=O)NC(=S)Nc1cc(Cl)cc(Cl)c1.ICI>>CC(C)C(=O)N1CS/C1=N\c1cc(Cl)cc(Cl)c1,,CC(C)=O,,CCN(CC)CC,,test
US05145970,CCCCOC(=O)/C=C\C(=O)OCCCC.Cc1cc(S)cc(C(C)(C)C)c1N>>CCCCOC(=O)CC(Sc1cc(C)c(N)c(C(C)(C)C)c1)C(=O)OCCCC,,Cc1ccccc1,,CCN(CC)CC,,test
US20100048568A1,Cc1cn(N)c2ccc(F)nc12.Cc1nc(-c2ncccn2)ncc1C(=O)O>>Cc1nc(-c2ncccn2)ncc1C(=O)Nn1cc(C)c2nc(F)ccc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060142580A1,COC(=O)c1ccc(C(Cl)Cl)cc1.Cc1ccc(N)cc1Nc1nccc(-c2cccnc2)n1>>Cc1ccc(NC(=O)c2ccc(C(Cl)Cl)cc2)cc1Nc1nccc(-c2cccnc2)n1,,Cc1ccccc1,,C[Al](C)C,,test
US20130317004A1,CS(=O)(=O)Cl.OC[C@H]1CO1>>CS(=O)(=O)OC[C@H]1CO1,,CN(C)C=O,,CCN(CC)CC,,test
US04868339,C=C(CCO)C1C(C)(C)C=C(C)CC1(C)C.CI>>C=C(CCOC)C1C(C)(C)C=C(C)CC1(C)C,,C1CCOC1,CCCCCC,[H-].[Na+],,test
US20110076291A1,CC(C)(C)OC(=O)N1CCNCC1.Fc1ccc(-n2ncnc2-c2cc3c(s2)-c2nc(Cl)ccc2OCC3)c(F)c1>>CC(C)(C)OC(=O)N1CCN(c2ccc3c(n2)-c2sc(-c4ncnn4-c4ccc(F)cc4F)cc2CCO3)CC1,,C1COCCO1,,,,test
US20060084815A1,CCOc1cc(C(N)CC#N)ccc1OC.O=C1OC(=O)c2c1ccc1ccccc21>>CCOc1cc(C(CC#N)N2C(=O)c3ccc4ccccc4c3C2=O)ccc1OC,,CC(=O)O,,,,test
US20070167421A1,CS(=O)(=O)c1nc(Cl)c(Cc2ccccc2)c(N2CCCC2)n1.c1cn[nH]c1>>Clc1nc(-n2cccn2)ncc1Cc1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04552696,C1CS1.COc1cccnc1.CS(=O)(=O)O>>COc1ccc[n+](CCS)c1.CS(=O)(=O)[O-],,O,,,,test
US20120149676A1,CNc1cc(Cl)c(C(=O)N[C@@H]2CC[C@@H](C(F)(F)F)CC2)cc1[N+](=O)[O-].FC1(F)CCNC1>>CNc1cc(N2CCC(F)(F)C2)c(C(=O)N[C@@H]2CC[C@@H](C(F)(F)F)CC2)cc1[N+](=O)[O-],,C1COCCO1,,CCN(C(C)C)C(C)C,Cl,test
US06429212B1,CC(C)c1cccc(C(C)C)c1N.O=C(O)c1ccc([N+](=O)[O-])cc1C(=O)O>>CC(C)c1cccc(C(C)C)c1N1C(=O)c2ccc([N+](=O)[O-])cc2C1=O,,CCOC(C)=O,,,,test
US20100016306A1,CC(C)(C)OC(=O)N1CCN(C(C)(C)CO)CC1.Cl>>CC(C)(CO)N1CCNCC1.Cl,,ClCCl,,,,test
US20090062536A1,CI.COc1nc(OC)nc(C(=O)c2cccc(Br)c2NS(=O)(=O)C(F)F)n1>>COc1nc(OC)nc(C(=O)c2cccc(Br)c2N(C)S(=O)(=O)C(F)F)n1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120028959A1,O=Cc1ccc(Br)cc1.OB(O)c1ccc(OC(F)(F)F)cc1>>O=Cc1ccc(-c2ccc(OC(F)(F)F)cc2)cc1,,O,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US04592866,CN1CC(CCCl)Oc2cc(Cl)ccc2C1=S.CNC.Cl>>CN(C)CCC1CN(C)C(=S)c2ccc(Cl)cc2O1.Cl,,CCO,Cl,,,test
US20100056640A1,C#CCOC(=O)c1cc(F)c(OCC#C)cc1F>>C#CCOc1cc(F)c(C(=O)O)cc1F,,CO,,Cl,[Na+].[OH-],test
US20140249126A1,COc1ccc(COC(=O)c2cn(C3CC3)c3cc(OCc4ccc(OC)cc4)c(OCc4ccc(OC)cc4)c(Cl)c3c2=O)cc1>>COc1ccc(COc2cc3c(c(Cl)c2OCc2ccc(OC)cc2)c(=O)c(C(=O)O)cn3C2CC2)cc1,,CO,O,[K+].[OH-],,test
US20070219234A1,COC(OC)N(C)C.COCC1CCCN(/C(C)=C(/C#N)C(N)=S)C1>>COCC1CCCN(c2cc[nH]c(=S)c2C#N)C1,,CN(C)C=O,,O,,test
US20090181942A1,CCOC(=O)CC1CCN(C(=O)CC2OC(c3cccc(OC)c3OCC)c3cc(Cl)ccc3-n3cccc32)CC1>>CCOc1c(OC)cccc1C1OC(CC(=O)N2CCC(CC(=O)O)CC2)c2cccn2-c2ccc(Cl)cc21,,CO,,O,O=C([O-])[O-].[K+].[K+],test
US20160016908A1,CC(=O)Cl.C[C@@H]1[C@@H](NC(=O)OCc2ccccc2)c2ncccc2N[C@H]1C>>CC(=O)N1c2cccnc2[C@H](NC(=O)OCc2ccccc2)[C@@H](C)[C@@H]1C,,ClCCl,,c1ccncc1,,test
US20100197591A1,CO.N#CC1=C(O)CCN(c2ccc(C3(C#N)CCC3)cc2)C1=O>>COC1=C(C#N)C(=O)N(c2ccc(C3(C#N)CCC3)cc2)CC1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US04438130,OCCCC1=CCC=CC1>>C1=CCC2(CC1)CCCO2,,O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20140213599A1,CC(C)(N)CO.Clc1cc(Cl)nc(Cl)n1>>CC(C)(CO)Nc1cc(Cl)nc(Cl)n1,,CC#N,,CCN(CC)CC,,test
US05861414,CC(C)(C)OC(=O)CN1CCC(c2n[nH]c3cc(Br)ccc23)CC1.CN(C)C=O.Fc1ccc(CBr)cc1>>CC(C)(C)OC(=O)CN1CCC(c2nn(Cc3ccc(F)cc3)c3cc(Br)ccc23)CC1.N,,CN(C)C=O,,O,[H-].[Na+],test
US20130059863A1,Cc1nc(N2CC[C@@H](N3CCC[C@@H]3C)C2)ccc1N1CCC2(CCC(O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)CC2)C1=O>>Cc1nc(N2CC[C@@H](N3CCC[C@@H]3C)C2)ccc1N1CCC2(CCC(O)CC2)C1=O,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20140121198A1,N#CCC[C@@H]1CC[C@@H](Nc2c([N+](=O)[O-])cnc3ccsc23)CC1>>N#CCC[C@@H]1CC[C@@H](Nc2c(N)cnc3ccsc23)CC1,[Pd],CO,,,,test
US20040034233A1,CC(=O)ON=C(C(=O)O)c1csc(N)n1>>CC(=O)ON=C(C(=O)O)c1csc(N)n1,,CC(C)=O,,O,O,test
US05432177,CN(C)c1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)cc1>>CN(C)c1ccc(N2CCNCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140256734A1,CC(C)(C)OC(=O)N1CC[C@H](Nc2nc(C#N)cc3ccc(F)cc23)C1.NN>>CC(C)(C)OC(=O)N1CC[C@H](Nc2nc(C(=N)NN)cc3ccc(F)cc23)C1,,CO,,O,,test
US20030213940A1,CC(C)(C)[Si](C)(C)Cl.O=C(OCC(F)(F)F)c1cccc(O)c1>>CC(C)(C)[Si](C)(C)Oc1cccc(C(=O)OCC(F)(F)F)c1,,O,,CN(C)C=O,c1c[nH]cn1,test
US20040058903A1,CCc1ccc(-c2ccccc2C(=O)Nc2ccc(NC(=O)Cc3csc(NC=O)n3)cc2)cc1>>CCc1ccc(-c2ccccc2C(=O)Nc2ccc(NC(=O)Cc3csc(N)n3)cc2)cc1,,CO,,Cl,,test
US20130171563A1,Cc1cc(O)c(C)c(CO)c1CO.Oc1cccc(O)c1>>Cc1cc(Cc2ccc(O)cc2O)c(C)cc1O,,CC(=O)O,Cc1ccccc1,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04198303,CO.OCc1ccccc1.[Ni]>>CO.Oc1ccccc1.[Ni],,c1ccccc1,,,,test
US20070232583A1,CC(C)OB(OC(C)C)OC(C)C.Cc1cc(-c2ccc(C(F)(F)F)cc2)nc(-c2cccc(Br)c2)c1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)nc(-c2cccc(B(O)O)c2)c1,,COC(C)(C)C,,[Li]CCCC,,test
US20120207763A1,CCC(CC)n1c(C(=O)OC)cc2cnc(Nc3ccc(N4CCN(C(C)=O)CC4)cc3)nc21>>O=C(O)c1cc2cnc(Nc3ccc(N4CCNCC4)cc3)nc2[nH]1,,C1CCOC1,,[Li+].[OH-],,test
US04571396,CCS.O=C(O)c1cn(C2CC2)c2nc(Cl)c(F)cc2c1=O>>CCSc1nc2c(cc1F)c(=O)c(C(=O)O)cn2C1CC1,,CCO,CN(C)C=O,[K+].[OH-],,test
US20030134849A1,CC(C)(C)O.O=C1CCC(=O)N1O.O=C=NS(=O)(=O)Cl>>CC(C)(C)OC(=O)NS(=O)(=O)ON1C(=O)CCC1=O,,ClCCl,,c1ccncc1,,test
US06180622B2,C=CCOC(=O)C1=C(S[C@H]2C[C@@H](C(O)c3ncc4sccn34)N(C(=O)OCC=C)C2)[C@H](C)[C@@H]2[C@@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)C(=O)N12>>C=CCOC(=O)C1=C(S[C@H]2C[C@@H](C(O)c3ncc4sccn34)N(C(=O)OCC=C)C2)[C@H](C)[C@@H]2[C@@H]([C@@H](C)O)C(=O)N12,,C1CCOC1,CCOC(C)=O,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20090075938A1,O=[N+]([O-])c1ccc2oc(SCc3ccc(Cl)cc3)nc2c1>>Nc1ccc2oc(SCc3ccc(Cl)cc3)nc2c1,[Fe],CCO,O,CCOC(C)=O,[Cl-].[NH4+],test
US20090275592A1,CC(C)(C)OC(=O)N[C@H](CCc1nc(-c2ccc3cnccc3c2)no1)Cc1ccc(C(F)(F)F)cc1>>N[C@H](CCc1nc(-c2ccc3cnccc3c2)no1)Cc1ccc(C(F)(F)F)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04981865,COC(=O)Cl.COc1ccc2c(c1)c(CNO)c(C)n2C(=O)c1ccc(Cl)cc1>>COC(=O)N(O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12,,C1COCCO1,O,CC(=O)[O-].[Na+],,test
US20030044399A1,COc1cc(C=O)c(OCc2ccccc2)cc1OC>>COc1cc(O)c(C=O)cc1OC,[Pd],CCOC(C)=O,,,,test
US20120172345A1,CC(C)(O)C#N.OCc1sc(N2CCOCC2)nc1Cc1ccc(Cl)c(Cl)c1>>N#CCc1sc(N2CCOCC2)nc1Cc1ccc(Cl)c(Cl)c1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20160158207A1,N#Cc1cc([N+](=O)[O-])c(F)cc1Br.OCCCl>>N#Cc1cc([N+](=O)[O-])c(OCCCl)cc1Br,,C1CCOC1,,O,CC(C)[N-]C(C)C.[Li+],test
US20160145199A1,C#CCO.N#CC#Cc1ccc(N)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>C#CCOC(=O)Nc1ccc(C#CC#N)cc1,,ClCCl,,CCN(CC)CC,,test
US20080161294A1,CCOC(=O)c1ccc(C(=O)NCC(C)=O)cc1Cl>>CCOC(=O)c1ccc(-c2ncc(C)o2)cc1Cl,,Cc1ccccc1,,O=P(Cl)(Cl)Cl,O=C([O-])O.[Na+],test
US20160022709A1,CC(C)(C)OC(=O)NCCN.O=C(O)CCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]>>CC(C)(C)OC(=O)NCCNC(=O)CCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-],,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20060111375A1,CC(C)CCOC(=O)c1ccccc1O.COc1cc2nccc(Cl)c2cc1OC>>COc1cc2nccc(Oc3ccccc3C(=O)OCCC(C)C)c2cc1OC,CN(C)c1ccncc1,Clc1ccccc1Cl,,,,test
US20070010528A1,C/N=c1\sc(C=O)c(CN2CCN(C(=O)OC(C)(C)C)CC2)n1C.C1COCCN1>>C/N=c1\sc(CN2CCOCC2)c(CN2CCN(C(=O)OC(C)(C)C)CC2)n1C,,CC(=O)O,ClCCCl,O=C([O-])[O-].[K+].[K+],,test
US20040209904A1,COC(=O)c1cc(Cl)ccc1[N+](=O)[O-].Oc1ccc(F)cc1F>>COC(=O)c1cc(Oc2ccc(F)cc2F)ccc1[N+](=O)[O-],,CN1CCCC1=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110275629A1,CCOC(=O)c1cc2cnn(Cc3ccc(OC)cc3)c(=O)c2n(C)c1=O>>CCOC(=O)c1cc2cn[nH]c(=O)c2n(C)c1=O,,O=C(O)C(F)(F)F,,,,test
US20110312999A1,CON(C)C(=O)c1csc(C2CCN(C(=O)OC(C)(C)C)CC2)n1.Cl[Mg]CC1CCCCC1>>CC(C)(C)OC(=O)N1CCC(c2nc(C(=O)CC3CCCCC3)cs2)CC1,,C1CCOC1,CCOCC,[Cl-].[NH4+],,test
US20070105905A1,CCC(=O)C(C)(C)Br.CCOC(=O)CS>>CCOC(=O)CSC(C)(C)C(=O)CC,,ClCCl,,CCN(CC)CC,,test
US20080214620A1,ClCc1ccc(Cl)cc1.Sc1nnc(-c2ccc3nc[nH]c3c2)o1>>Clc1ccc(CSc2nnc(-c3ccc4[nH]cnc4c3)o2)cc1,,CCO,,,,test
US20040077707A1,O=[N+]([O-])C=Cc1ccc(Cl)cc1Cl.[C-]#[N+]CC(=O)OCc1ccccc1>>O=C(OCc1ccccc1)c1[nH]ccc1-c1ccc(Cl)cc1Cl,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US04108667,CC(C)=C1CCCC1=O.[O-][Cl+3]([O-])([O-])[O-].c1ccc2c[nH+]ccc2c1>>Cc1cc2[n+](c3c1=CC=C3)CC=c1ccccc1=2.[O-][Cl+3]([O-])([O-])[O-],,CN(C)C=O,CO,,,test
US20110082183A1,CC(=O)O.N=C(N)NN.O=CC=Cc1cccn1-c1ccccc1Br>>CC(=O)[O-].NC(=[NH2+])NN=CC=Cc1cccn1-c1ccccc1Br,,CCO,,O=C(O)O,,test
US20040142969A1,Cc1c(O)cccc1C(=O)O.OB(O)c1cccc(F)c1>>COC(=O)c1cccc(Oc2cccc(F)c2)c1,,ClCCl,,c1ccncc1,,test
US20060183769A1,CN1C2CCC1CC(=O)C2.NO>>CN1C2CCC1CC(=NO)C2,,CCO,,Cl,,test
US20010027196A1,CS(=O)c1nc(N)nc(-c2ccco2)c1Br.OC1CCCCC1>>Nc1nc(Oc2ccccc2)c(Br)c(-c2ccco2)n1,,C1COCCO1,,C1CCC2=NCCCN2CC1,,test
US20090264432A1,COCCCCC(c1cccc(F)c1-c1cccc(C)c1)[C@H]1CN(C(=O)OC(C)(C)C)CCO1.Cl>>COCCCCC(c1cccc(F)c1-c1cccc(C)c1)[C@H]1CNCCO1.Cl,,CO,,,,test
US20160176850A1,COC[C@@H](C)O.O=C(NC1CCC1)c1nc(Cl)cc(N2CCC(c3n[nH]c4ncccc34)CC2)n1>>COC[C@@H](C)Oc1cc(N2CCC(c3n[nH]c4ncccc34)CC2)nc(C(=O)NC2CCC2)n1,,C1CCOC1,CCOC(C)=O,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20120264735A1,COCCC(=O)O.Cn1cc(-n2ccc(=O)c(Cc3cccc(-c4ncc(N)cn4)c3)n2)cn1>>COCCC(=O)Nc1cnc(-c2cccc(Cc3nn(-c4cnn(C)c4)ccc3=O)c2)nc1,,CN(C)C=O,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US04920132,O=C(O)c1ccc(COc2ccc(SCc3ccc4ccccc4n3)cc2)cc1.O=C(OO)c1cccc(Cl)c1>>O=C(O)c1ccc(COc2ccc(S(=O)Cc3ccc4ccccc4n3)cc2)cc1,,CC(Cl)Cl,,O=C([O-])O.[K+],,test
US20160221994A1,CC(=O)c1ccc(-c2cc(Cl)c3c(c2)CC(CNC(=O)OC(C)(C)C)O3)s1.CCN=C=NCCCN(C)C.CN(C)C=O.On1nnc2ccccc21>>CC(=O)c1ccc(-c2cc(Cl)c3c(c2)CC(CNC(=O)/C=C/c2cnccc2N)O3)s1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,,test
US05892104,CC1=CC(C)(C)CC(O)CC1.CCI>>CCOC1=CC(C)(C)CC(C)CC1,,Cc1ccccc1,,[H-].[Na+],,test
US20050004134A1,CC(C)N.CCOC(=O)c1nc(-c2ccccc2)c(-c2ccc(=O)n(CCOC)n2)s1>>COCCn1nc(-c2sc(C(=O)NC(C)C)nc2-c2ccccc2)ccc1=O,,C1CCOC1,,,,test
US20070135631A1,CC(C)(C)[S@](N)=O.O=C(c1ccc(F)cc1)c1cc(F)cc(OC(F)(F)C(F)F)c1>>CC(C)(C)[S@@](=O)N=C(c1ccc(F)cc1)c1cc(F)cc(OC(F)(F)C(F)F)c1,,C1CCOC1,,,,test
US20160039834A1,CN.Cc1noc(C)c1-c1nc(-c2cc(OC[C@H]3CO3)ccc2C(F)(F)F)nc(N2Cc3cncnc3C2)c1C>>CNC[C@@H](O)COc1ccc(C(F)(F)F)c(-c2nc(-c3c(C)noc3C)c(C)c(N3Cc4cncnc4C3)n2)c1,,CO,,,,test
US04721791,Cc1cc(C)cc(I)c1.FC(F)(F)I>>Cc1cc(C)cc(C(F)(F)F)c1,[Cu],CN(C)C=O,O,,,test
US20150291595A1,COc1ccc(S(=O)(=O)Nc2cc(Br)cnc2Cl)cc1>>O=S(=O)(Nc1cc(Br)cnc1Cl)c1ccc(O)cc1,,ClCCl,,BrB(Br)Br,,test
US20080045544A1,CC(C)(C)OC(=O)N1CCC(N(C(=O)OC(C)(C)C)c2ccc(OCC#N)cn2)CC1>>N#CCOc1ccc(NC2CCNCC2)nc1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20090192156A1,CCOC1CCNCC1.Cc1[nH]c(C)c2c(=O)[nH]nc(Cc3cccc(C(=O)O)c3)c12>>CCOC1CCN(C(=O)c2cccc(Cc3n[nH]c(=O)c4c(C)[nH]c(C)c34)c2)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US20100137299A1,CC(C)(C)OC(=O)N1CCCC(CCN2C(=O)C3(COc4cc5c(cc43)OCO5)c3ccccc32)C1>>O=C1N(CCC2CCCNC2)c2ccccc2C12COc1cc3c(cc12)OCO3,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080300242A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)[C@H]1CN(Cc2ccccc2)CCN1>>CC(C)[C@H]1CNCCN1C(=O)OC(C)(C)C,,ClCCl,,,,test
US20080255347A1,CNCCc1ccc(O)cc1.COc1cc(Br)c(C(=O)Cl)cc1O>>COc1cc(Br)c(C(=O)N(C)CCc2ccc(O)cc2)cc1O,,ClCCl,,,,test
US20070066612A1,Cc1nc(NCc2ccc(C(F)(F)F)cc2)nc(N)c1[N+](=O)[O-]>>Cc1nc(NCc2ccc(C(F)(F)F)cc2)nc(N)c1N,[Zn],C1CCOC1,CC(=O)O,,,test
US20100063079A1,CS(=O)(=O)Nc1cc(NCCO)nc(SCc2ccccc2)n1.NC(CO)CO>>CS(=O)(=O)Nc1cc(NC(CO)CO)nc(SCc2ccccc2)n1,,CN1CCCC1=O,,CCOC(C)=O,O,test
US20030004181A1,CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CCc1ccc(C(=N)N)cc1)n2C)c1ccccn1.O=C(Cl)c1ccccc1>>CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CCc1ccc(C(=N)NC(=O)c3ccccc3)cc1)n2C)c1ccccn1,,CO,ClCCl,Cl,,test
US20020183353A1,C1=C(c2c[nH]c3ccccc23)CCNC1.Cc1ccc(S(=O)(=O)OC[C@H]2COc3ccc4c(c3O2)CCO4)cc1>>C1=C(c2c[nH]c3ccccc23)CCN(CC2COc3ccc4c(c3O2)CCO4)C1,,CS(C)=O,,CCOC(C)=O,,test
US20150191483A1,CC(C)(C)OC(=O)N1CC[C@](c2ccc(C(O)(C(F)(F)F)C(F)(F)F)c(F)c2)(S(=O)(=O)c2ccc(F)cc2)C1.CI>>COC(c1ccc([C@]2(S(=O)(=O)c3ccc(F)cc3)CCN(C(=O)OC(C)(C)C)C2)cc1F)(C(F)(F)F)C(F)(F)F,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20050096306A1,CC(C)(C)OC(=O)NCC[C@H](O)C(=O)Nc1cnn(CCO)c1NC(c1ccccc1)(c1ccccc1)c1ccccc1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)NCC[C@H](O)C(=O)Nc1cnn(CCOC(c2ccccc2)(c2ccccc2)c2ccccc2)c1NC(c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)c1ccncc1,CN(C)C=O,,CCN(CC)CC,O,test
US05965591,CC(C)(C)OC(=O)NCCS.Fc1ccc2onc(Cl)c2c1>>Cl.NCCSc1noc2ccc(F)cc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140161736A1,COC(=O)c1cc(CO)n(C)n1.CS(=O)(=O)Cl>>COC(=O)c1cc(COS(C)(=O)=O)n(C)n1,,ClCCl,,CCN(CC)CC,,test
US20110245205A1,O=C(c1ccnc(Cl)n1)C1CC1>>OC(c1ccnc(Cl)n1)C1CC1,,CCOC(C)=O,CO,[BH4-].[Na+],,test
US20080300270A1,C/C(N)=C\C#N.CCCC1CC(=O)CC(=O)C1.COC(=O)c1cc(C=O)cc(Br)c1OCc1cccc(OC)c1>>CCCC1CC(=O)C2=C(C1)NC(C)=C(C#N)C2c1cc(Br)c(OCc2cccc(OC)c2)c(C(=O)OC)c1,,CCO,,,,test
US20130079324A1,C=CC(=O)N[C@@H]1C[C@@H](Oc2nc(Nc3cnn(C)c3)nc3c2c(C#N)cn3COCC[Si](C)(C)C)C1>>C=CC(=O)NC1CC(Oc2nc(Nc3cnn(C)c3)nc3[nH]cc(C#N)c23)C1,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20150284395A1,CCOC(=O)CC(=O)c1ccc(Cl)c(Cl)c1.Cn1nccc1-c1cn[nH]c1N>>Cn1nccc1-c1cnn2c(=O)cc(-c3ccc(Cl)c(Cl)c3)[nH]c12,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20020040040A1,Cc1ccccc1-c1cc(CO)ncc1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1.Oc1cccc(C(F)(F)F)c1>>Cc1ccccc1-c1cc(COc2cccc(C(F)(F)F)c2)ncc1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110137068A1,CCI.COC(=O)c1cccc(NC(=O)c2ccccc2)c1F>>CCN(C(=O)c1ccccc1)c1cccc(C(=O)OC)c1F,,CN(C)C=O,,O,[H-].[Na+],test
US20120230951A1,COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc2cc(Br)ccc2[nH]1)C(C)C.OB(O)c1ccc(Cl)cc1>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc2cc(-c3ccc(Cl)cc3)ccc2[nH]1)C(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US06262082B1,CCCCC([Sn])=C(CCCC)CCCC.Nc1ccc(I)c(Cl)c1>>C=Cc1ccc(N)cc1Cl,,C1CCOC1,,,,test
US20080171743A1,C[C@H]1COCCN1c1cc(CS(=O)(=O)c2ccccc2)nc(-c2ccc(N)cc2)n1.O=C(Cl)Oc1ccccc1>>C[C@H]1COCCN1c1cc(CS(=O)(=O)c2ccccc2)nc(-c2ccc(NC(=O)Oc3ccccc3)cc2)n1,,C1COCCO1,,O=C([O-])O.[Na+],,test
US20120088755A1,Cc1cc(O)cc2[nH]cnc12.Clc1cc(Cl)ncn1>>Cc1cc(Oc2cc(Cl)ncn2)cc2[nH]cnc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030073836A1,NCc1ccc(-c2ccccc2)cc1.O=C(Cl)c1ccc([N+](=O)[O-])s1>>O=C(NCc1ccc(-c2ccccc2)cc1)c1ccc([N+](=O)[O-])s1,,C1CCOC1,,CCN(CC)CC,,test
US07026336B1,C=CS(=O)(=O)Cl.C=CS(=O)(=O)NCC(C)(C)c1nc(-c2ccc(Cl)c(OC)c2)c(-c2ccncc2)[nH]1.CCN(CC)CC.COc1cc(-c2nc(C(C)(C)CN)[nH]c2-c2ccncc2)ccc1Cl>>CN1CCN(CCS(=O)(=O)NCC(C)(C)c2nc(-c3ccc(Cl)c(O)c3)c(-c3ccncc3)[nH]2)CC1,,ClCCl,,,,test
US20050070592A1,Cc1c(-c2ccccc2)n(C)c2ccc(-c3ccc(OCC#N)cc3)cc12.[N-]=[N+]=[N-]>>Cc1c(-c2ccccc2)n(C)c2ccc(-c3ccc(OCc4nnn[nH]4)cc3)cc12,,CN(C)C=O,,[Cl-].[NH4+],,test
US20130005707A1,Cc1ccc(S(=O)(=O)Cl)cc1.Cc1n[nH]c2cc(Br)ccc12>>Cc1ccc(S(=O)(=O)n2nc(C)c3ccc(Br)cc32)cc1,,C1COCCO1,,[H-].[Na+],,test
US20150218147A1,CC(=O)N[C@H]1CN[C@@H](CO)[C@@H]1O.CCCC=O>>CCCCN1C[C@H](NC(C)=O)[C@@H](O)[C@@H]1CO,,CO,,[BH3-]C#N.[Na+],,test
US20140031362A1,CCOC(=O)C1=C(c2c(F)ccc(F)c2F)Nc2[nH]nc(-c3cccs3)c2C1c1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)cc1>>O=C1c2cc(N3CCNCC3)ccc2-c2c1c(-c1c(F)ccc(F)c1F)nc1[nH]nc(-c3cccs3)c21,,Cc1ccccc1C,,O=C([O-])O.[Na+],,test
US20130090342A1,CC(=O)Nc1ccc(C(C)=O)cc1-c1ccc(-n2c(=N)n(Cc3cccc4[nH]ccc34)c3ccccc32)cc1>>CC(=O)Nc1ccc(C(C)O)cc1-c1ccc(-n2c(=N)n(Cc3cccc4[nH]ccc34)c3ccccc32)cc1,,CO,,[BH4-].[Na+],,test
US20150225373A1,C#CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)n(-c2ccc(C)cc2)n1.Nc1cc(C(=O)NCCN2CCOCC2)cc(C(F)(F)F)c1>>C#CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(C(=O)NCCN5CCOCC5)cc(C(F)(F)F)c4)n3)c3ccccc23)n(-c2ccc(C)cc2)n1,,C1CCOC1,CN(C)C=O,,,test
US04873236,CCN(CC)CC1CCCCN1CCN.O=C1Nc2cccnc2N(C(=O)Cl)c2ccccc21>>CCN(CC)CC1CCCCN1CCNC(=O)N1c2ccccc2C(=O)Nc2cccnc21.Cl,,CC#N,,,,test
US20070106095A1,CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc2ccc(OCc3ccccc3)cc2o1>>CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc2ccc(O)cc2o1,[Pd],CCOC(C)=O,CO,,,test
US20160102071A1,CC#C[C@@H](CC(=O)OCC)c1ccc(OCc2ccc3scc(-c4ccccc4Br)c3c2)cc1>>CC#C[C@@H](CC(=O)O)c1ccc(OCc2ccc3scc(-c4ccccc4Br)c3c2)cc1,,CCO,,Cl,[Li+].[OH-],test
US20080255155A1,CC(=O)Nc1ccc(N)cn1.O=C=Nc1cccc([N+](=O)[O-])c1>>CC(=O)Nc1ccc(NC(=O)Nc2cccc([N+](=O)[O-])c2)cn1,,C1CCOC1,,,,test
US20030018032A1,Nc1cnccn1.O=Cc1cccc(Cl)c1Cl.[C-]#[N+]CCCC>>CCCCNc1c(-c2cccc(Cl)c2Cl)nc2cnccn12,,[O-][Cl+3]([O-])([O-])O,,,,test
US20160108036A1,CCOC(=O)C(Cl)C(C)=O.NC(=S)Cc1ccc(Br)cc1>>CCOC(=O)c1sc(Cc2ccc(Br)cc2)nc1C,,CCO,c1ccncc1,,,test
US05194610,CCOC(=O)c1ccccc1S(=O)(=O)N=C=O.CNc1nc(N)nc(OC(F)(F)F)n1>>CCOC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(NC)nc(OC(F)(F)F)n1,,ClCCl,,,,test
US20130059853A1,CC1(C)OB(c2ccc3c(c2)COC3=O)OC1(C)C.COc1ccc(Br)c(OC)c1OCC1CC1>>COc1ccc(-c2ccc3c(c2)COC3=O)c(OC)c1OCC1CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070299111A1,CCOC1(O[Si](C)(C)C)CC1.C[C@](O)(c1ccc(C(=O)N(C2CCNCC2)C2CC2)cc1)C(F)(F)F>>C[C@](O)(c1ccc(C(=O)N(C2CC2)C2CCN(C3CC3)CC2)cc1)C(F)(F)F,,CCOC(C)=O,CO,CC(=O)O,[BH3-]C#N.[Na+],test
US05856518,CCOC(=O)C1(C=O)CC1.Cc1ccc(C[C@H](N)c2ccccc2)cc1.[C-]#N>>CCOC(=O)C1(C(C#N)N[C@@H](Cc2ccc(C)cc2)c2ccccc2)CC1,,CCO,O,Cl,,test
US20160046624A1,CC(C)Oc1cnc2c(c1Cc1ccc(Cl)cc1)c(=O)n(CCCOC=O)c(=O)n2C>>CC(C)Oc1cnc2c(c1Cc1ccc(Cl)cc1)c(=O)n(CCCO)c(=O)n2C,,C1CCOC1,O,[Li]O,,test
US20150175530A1,COC(=O)[C@@H](NC(=O)c1ccc(C#C/C=C/C(O)CO)cc1)C(C)(C)N.NO>>CC(C)(N)[C@H](NC(=O)c1ccc(C#C/C=C/C(O)CO)cc1)C(=O)NO,,CC(C)O,O,CC(=O)O,,test
US20070185089A1,CC(C)(C)OC(=O)N1CCc2ccc(B3OC(C)(C)C(C)(C)O3)cc2CC1.CNC(=O)Cc1ccc(Br)cc1>>CNC(=O)Cc1ccc(-c2ccc3c(c2)CCN(C(=O)OC(C)(C)C)CC3)cc1,,CCOC(C)=O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US06004724,COc1ccc(CC#N)cc1.O=[N+]([O-])c1ccccc1>>COc1ccc(C(C#N)=C2C=CC(=NO)C=C2)cc1,,CO,O,CC(=O)O,[K+].[OH-],test
US05607928,COc1ccc2c(c1)C(=O)CCC2.NO>>ON=C1CCCc2ccccc21,,c1ccncc1,,Cl,O,test
US05280032,CC(=O)OC(C)=O.CC(C)(C)OCCOCC(O)c1cccc(Cl)c1>>CC(=O)OC(COCCOC(C)(C)C)c1cccc(Cl)c1,,ClCCl,,Cl,c1ccncc1,test
US20140275179A1,C=C(C)c1snc(-c2ccc(CC)cc2)c1C(=O)OCC>>C=C(C)c1snc(-c2ccc(CC)cc2)c1CO,,Cc1ccccc1,,CC(C)C[AlH]CC(C)C,,test
US04472446,CC(S)CS.CCC=S>>CSCC1SCC(C)S1,,C1CCCCC1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20010001799A1,CCc1ccccc1O.II>>CCc1cc(I)ccc1O,Cl[Cu]Cl,Clc1ccccc1,,,,test
US20160122342A1,CCN(c1cccc2c1CC=CCCc1cc(C)[nH]c(=O)c1CNC2=O)[C@@H]1CC[C@@H](N)CC1.O=S(=O)(OCC(F)F)C(F)(F)F>>CCN(c1cccc2c1CC=CCCc1cc(C)[nH]c(=O)c1CNC2=O)[C@@H]1CC[C@@H](NCC(F)F)CC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20070173498A1,CN(C)CC1CCc2cc(O)ccc2C1.O=[N+]([O-])c1ccc(CO)cc1>>CN(C)CC1CCc2cc(OCc3ccc([N+](=O)[O-])cc3)ccc2C1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020037910A1,Nc1ccc(F)cc1F.O=C(O)CCCCBr>>O=C(CCCCBr)Nc1ccc(F)cc1F,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20160096839A1,C=CC[C@H](NC(=O)OC(C)(C)C)c1cccc(-c2ncc(OC)cc2NC(=O)[C@H](C)C=C)c1>>COc1cnc2c(c1)NC(=O)[C@H](C)C=CC[C@H](NC(=O)OC(C)(C)C)c1cccc-2c1,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,ClCCCl,,,,test
US20120108627A1,CC(C)(C#N)c1ccc(-n2c(=O)[nH]c3cnc4ccc(Cl)cc4c32)cc1.Cc1cccc(S(=O)(=O)Cl)c1>>Cc1cccc(S(=O)(=O)n2c(=O)n(-c3ccc(C(C)(C)C#N)cc3)c3c4cc(Cl)ccc4ncc32)c1,,ClCCl,,CCN(CC)CC,O,test
US20070161640A1,CC(C)(C)[Si](C)(C)N1C(=O)C[C@H]1C(=O)OCc1ccccc1>>CC(C)(C)[Si](C)(C)N1C(=O)C[C@H]1C(=O)O,[Pd],CO,,,,test
US20050124679A1,NCc1ccc(CO)cc1.O=C(O)c1ccc(N2CCCC2)cc1>>O=C(NCc1ccc(CO)cc1)c1ccc(N2CCCC2)cc1,CN(C)c1ccncc1,c1ccncc1,,ClCCCl,On1nnc2ccccc21,test
US20070197526A1,CCOC(=O)c1cc(C)nn1-c1ccc(OC)cc1>>COc1ccc(-n2nc(C)cc2C(=O)O)cc1,,CCO,O,Cl,[Na+].[OH-],test
US20030176486A1,BrCCCCCBr.O=S([O-])[O-].[Na+]>>O=S(=O)([O-])CCCCCBr.[Na+],,O,,CCO,,test
US05273975,CCCN(CCC)C1Cc2cccc3c2N(C1)C(=O)C3>>CCCN(CCC)C1Cc2cccc3c2N(CC3)C1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06391901B1,N#CCCCBr.Oc1ccc(-c2sc3cc(OCc4ccccc4)ccc3c2Cc2ccc(OCCN3CCCC3)cc2)cc1>>N#CCCCOc1ccc(-c2sc3cc(O)ccc3c2Cc2ccc(OCCN3CCCC3)cc2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20110172256A1,CI.Clc1ccc2c(Br)cccc2n1>>Cc1cc2c(Br)cccc2nc1Cl,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US06713471B1,Cc1ccccc1S.O=C1CCO1>>Cc1ccccc1SCCC(=O)O,,CC#N,,,,test
US20030004202A1,CCOC(=O)C(CC1(OC)C=C2OCOC2=CC1)C(=O)OCC>>CCOC(=O)C(CC1(OC)C=C2OCOC2=CC1)C(=O)O,,CCO,O,[K+].[OH-],,test
US20090203692A1,O=C1CSC(Nc2cc(S(=O)(=O)NC3CCC3)ccc2Cl)=N1.O=Cc1ccc2ncccc2c1>>O=C1N=C(Nc2cc(S(=O)(=O)NC3CCC3)ccc2Cl)S/C1=C\c1ccc2ncccc2c1,,CCO,,C1CCNCC1,Cl,test
US20080176843A1,CC(C)CC=O.O=C1Nc2ccccc2C2(CCNCC2)O1>>CC(C)CCN1CCC2(CC1)OC(=O)Nc1ccccc12,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20110086834A1,C=Cc1csc(C(C)=O)c1>>CCc1csc(C(C)=O)c1,[Pd],CO,,,,test
US20070207997A1,Brc1cccnc1.NC(=O)c1cc2c(nc1N)[nH]c1ccccc12>>NC(=O)c1cc2c3ccccc3n(-c3cccnc3)c2nc1N,[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20080176829A1,CC(C)(C)OC(=O)N1CCOc2ccc3[nH]ccc3c2C1.Cc1ccc(F)cc1S(=O)(=O)Cl>>Cc1ccc(F)cc1S(=O)(=O)n1ccc2c3c(ccc21)OCCNC3,,CO,N,CN(C)C=O,[H-].[Na+],test
US06140274,C=CCCl.OCCCCCO>>OCCCCCOC=CCCl,,O,,[H][H],[H-].[Na+],test
US06069156,COC(=O)C=Cc1c[nH]c2cc(C(=O)OC)ccc12>>COC(=O)CCc1c[nH]c2cc(C(=O)OC)ccc12,[Pd],C1COCCO1,CO,,,test
US20140343278A1,CCOC(=O)/C=C/c1ccc2c(c1)N(C)C(=O)C(C)(C)C(=O)N2CC>>CCOC(=O)CCc1ccc2c(c1)N(C)C(=O)C(C)(C)C(=O)N2CC,[Pd],CO,,,,test
US20080021056A1,CC(=O)O.CC(=O)O[BH-](OC(C)=O)OC(C)=O.CCCCOC(=O)CC(C)=O.Nc1ccc(F)cc1>>CC(CC(=O)OC(C)(C)C)Nc1ccc(F)cc1,,ClCCCl,,O=C([O-])O.[Na+],,test
US20080293731A1,CC(=O)O[C@H]1CCN2CCC[C@@H]1C2>>O[C@H]1CCN2CCC[C@@H]1C2,,[Na+],[OH-],,,test
US20130172549A1,CS(=O)(=O)OCCc1cn2c(C(=O)NCC34CC5CC(CC(C5)C3)C4)cccc2n1.OC1CCNCC1>>O=C(NCC12CC3CC(CC(C3)C1)C2)c1cccc2nc(CCN3CCC(O)CC3)cn12,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140094474A1,CCOC(=O)c1cn2c(C)nc(C)cc2n1>>Cc1cc2nc(C(=O)O)cn2c(C)n1,,CCO,,[Na+].[OH-],,test
US20150250767A1,C1CCOC1.COc1cc(C)c2c(ccn2C(=O)OC(C)(C)C)c1CC#N>>COc1cc(C)c2c(ccn2C(=O)OC(C)(C)C)c1C(C)C#N,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20050080272A1,Cc1ccc(S)cc1.O=[N+]([O-])C(=C(Cl)Cl)C(Cl)=C(Cl)Cl>>Cc1ccc(SC(Cl)=C(C(Cl)=C(Cl)Cl)[N+](=O)[O-])cc1,,CCOCC,,CO,,test
US20060111445A1,CCCCCCc1cc2c(cc1O)C(=O)CC2.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCCCCCc1cc2c(cc1OS(=O)(=O)C(F)(F)F)C(=O)CC2,,c1ccncc1,,Cl,,test
US20110212962A1,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCI)c3ccccc23)cc1.O=[N+]([O-])c1c[nH]cn1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCn3cnc([N+](=O)[O-])c3)c3ccccc23)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080234262A1,CNC(=O)Nc1ccc(-c2nc(N3CCOCC3)c3cnn(C4CCN(C(=O)OC(C)(C)C)CC4)c3n2)cc1>>CNC(=O)Nc1ccc(-c2nc(N3CCOCC3)c3cnn(C4CCNCC4)c3n2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06291475B1,CCOC(=O)Cl.N#Cc1ccc(OCC(O)CN2CC3CNCC(C3)C2)cc1>>CCOC(=O)N1CC2CC(CN(CC(O)COc3ccc(C#N)cc3)C2)C1,,ClCCl,,[Na+].[OH-],,test
US20090042929A1,CC(C(=O)O)(c1ccccc1)c1ccccc1.NCCc1cccs1>>CC(C(=O)NCCc1cccs1)(c1ccccc1)c1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US20150175600A1,CCn1c(-c2nc3cc(C(=O)N4CCC[C@@H](N)C4)ccc3n2C)cc2cc(OC)cnc21>>CCn1c(-c2nc3cc(C(=O)N4CCC[C@@H](N)C4)ccc3n2C)cc2cc(O)cnc21,,CS(C)=O,ClCCl,BrB(Br)Br,,test
US05112869,COc1ccc(C2(c3ccc(OC)c(OC)c3)CCC(=O)O2)cc1OC>>Oc1ccc(-c2ccc(O)c3cc(O)c(O)cc23)cc1O,,ClCCl,,BrB(Br)Br,,test
US20110092612A1,C=CC(=O)Cl.Oc1ccc2cc(-c3cccc4c3sc3ccccc34)ccc2c1-c1cccc2c1sc1ccccc12>>C=CC(=O)Oc1ccc2cc(-c3cccc4c3sc3ccccc34)ccc2c1-c1cccc2c1sc1ccccc12,,CCOC(C)=O,O,C1CCOC1,CCN(CC)CC,test
US20070185103A1,COC(=O)c1cc(Br)c(=O)n(C2CCCC2)c1>>COC(=O)c1ccc(=O)n(C2CCCC2)c1,[Pd],CO,,,,test
US05631269,O=C1CN2CCC1CC2.O=Cc1ccc(Cl)cc1>>O=C1C(=Cc2ccc(Cl)cc2)N2CCC1CC2,,CCO,,O,[Na+].[OH-],test
US20110136800A1,NC(=O)c1cccc2c1[C@H]1CCCN(C(=O)c3ccc4[nH]cnc4c3)[C@H]1CC2>>N#Cc1cccc2c1[C@H]1CCCN(C(=O)c3ccc4[nH]cnc4c3)[C@H]1CC2,,CO,ClCCl,,,test
US20040209928A1,C=Cc1ccc(C(=O)NCCC(=O)OCC)cc1.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)CCNC(=O)c1ccc(C2CO2)cc1,,ClC(Cl)Cl,,,,test
US05578604,CCCC[Sn](C#C[Si](C)(C)C)(CCCC)CCCC.CCOC(=O)c1cn(C2CC2)c2c(F)c(F)c(F)c(Br)c2c1=O>>CCOC(=O)c1cn(C2CC2)c2c(F)c(F)c(F)c(C#C[Si](C)(C)C)c2c1=O,,Cc1ccccc1,,,,test
US04880457,C[S+](C)(C)=O.O=C(c1ccc(F)cc1)c1ccc(F)cc1>>Fc1ccc(C2(c3ccc(F)cc3)CO2)cc1,,CS(C)=O,,[H-].[Na+],,test
US04873253,CCOC(=O)Cl.CN(C)C=O.O=C(O)c1cccc(Oc2ccc(Br)cn2)c1>>NC(Cc1cccc(Oc2ccccc2)c1)C(=O)O,,C1CCOC1,,CCN(CC)CC,,test
US20070191333A1,CC1(CNC(=O)C(F)(F)F)CN(C(c2ccccc2)c2ccccc2)C1.Cl>>CC1(CNC(=O)C(F)(F)F)CNC1.Cl,[Pd],CO,,,,test
US20110183985A1,CCN(CC)/N=N/c1c(C#C[Si](C)(C)C)c(F)cc(C(C)=O)c1-c1cccc(F)c1>>C#Cc1c(F)cc(C(C)=O)c(-c2cccc(F)c2)c1/N=N/N(CC)CC,,C1CCOC1,CO,O=C([O-])[O-].[K+].[K+],,test
US04931581,CCC(C)=O.NNC(=O)c1cccc2nnsc12>>CCC(C)=NNC(=O)c1cccc2nnsc12,,CC(=O)O,,,,test
US20110306621A1,CCOC(=O)Cl.COC(=O)c1ccc2c(c1)C(=O)C(F)CC2>>CCOC(=O)OC1=C(F)CCc2ccc(C(=O)OC)cc21,,[Cl-],[NH4+],C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US04352818,CN1Cc2c(Cl)ncn2-c2ccccc2C1=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CN1Cc2c(Cl)ncn2-c2ccccc2C1=S,,Cc1ccccc1,,,,test
US20080255128A1,CC1C(=O)N(c2cc(Cc3n[nH]c(=O)c4ccccc34)ccc2F)C(=O)N1CCN1CCCC1.O=S(=O)(O)O>>CC1C(=O)N(c2cc(Cc3n[nH]c(=O)c4ccccc34)ccc2F)C(=O)N1CCN1CCCC1.O=S(=O)(O)O,,CO,,,,test
US20070213331A1,CCCN(C)C(=O)c1cc(C(=O)OCC)cc(C(F)F)c1>>CCCN(C)C(=O)c1cc(C(=O)O)cc(C(F)F)c1,,C1CCOC1,,[Li+].[OH-],,test
US20090298823A1,Clc1nc(Cl)c2cc[nH]c2n1.NCCCCCN>>NCCCCCNc1nc(Cl)nc2[nH]ccc12,,CCCCO,,CCN(CC)CC,,test
US06329381B1,N#CCCCCl.Nc1nc(S)nc2c1nc(O)n2Cc1ccccc1>>N#CCCCSc1nc(N)c2nc(O)n(Cc3ccccc3)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080293711A1,CI.COC(=O)c1ccc(NN=Cc2ccccc2)cc1>>COC(=O)c1ccc(N(C)N=Cc2ccccc2)cc1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20040209948A1,CCOC(=O)N1CCC(NS(=O)(=O)c2ccc(C(C)=O)c3ccccc23)CC1.NC1CCCCC1>>CCOC(=O)N1CCC(NS(=O)(=O)c2ccc(C(C)NC3CCCCC3)c3ccccc23)CC1,,CO,,[BH3-]C#N.[Na+],,test
US20100298356A1,COC(=O)C(Cl)SC.Oc1ccc2ncc(Br)cc2c1>>COC(=O)C(Oc1ccc2ncc(Br)cc2c1)SC,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20150175604A1,CC(C)(C)[Si](C)(C)Cl.OCc1cc2nc(Cl)ccc2n1Cc1ccccc1>>CC(C)(C)[Si](C)(C)OCc1cc2nc(Cl)ccc2n1Cc1ccccc1,,ClCCl,,c1c[nH]cn1,,test
US20080176872A1,C[C@H](N)c1ccc(F)cc1.O=[N+]([O-])c1cnc(Cl)cc1Nc1cc(C2CC2)[nH]n1>>C[C@H](Nc1cc(Nc2cc(C3CC3)[nH]n2)c([N+](=O)[O-])cn1)c1ccc(F)cc1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US04548940,CSc1ncc(Cc2ccncc2)c(=O)[nH]1.Cc1cc(Cl)cnc1NCCCN>>Cc1cc(Cl)cnc1NCCCNc1ncc(Cc2ccncc2)c(=O)[nH]1,,c1ccncc1,,,,test
US20150291595A1,COc1ccc(C(=O)Cl)cc1.Nc1cncc(Br)c1>>COc1ccc(C(=O)Nc2cncc(Br)c2)cc1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20050014812A1,CC(=O)Oc1ccc(CBr)c(Cl)c1.CCOC(=O)CCCOc1cc(C)c2nc(C)[nH]c2c1>>CCOC(=O)CCCOc1cc(C)c2nc(C)n(Cc3ccc(OC(C)=O)cc3Cl)c2c1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04464300,Cl.NCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1F)=CC2>>Cl.NCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1F)=CC2,,CC(C)O,,,,test
US05242895,CCOC(=O)C(C)Br.COC(=O)c1c(C=NO)cccc1Oc1nc(OC)cc(OC)n1>>CCOC(=O)C(C)ON=Cc1cccc(Oc2nc(OC)cc(OC)n2)c1C(=O)OC,O=[Ag],CC(C)=O,,,,test
US04190571,CCOC(=O)C(C)(C)Br.Nc1ccccc1N>>CC1(C)NC2CCCCC2NC1=O,,CCO,,,,test
US06239131B1,Cc1ccc2c(c1)N(CC(=O)c1ccccc1C)C(=O)C(NC(=O)OC(C)(C)C)CN2C(=O)CC(C)(C)C>>Cc1ccc2c(c1)N(CC(=O)c1ccccc1C)C(=O)C(N)CN2C(=O)CC(C)(C)C,,C1COCCO1,Cl,,,test
US20140171423A1,FC(F)(F)c1ccc(Br)nc1.O=C1CCNC[C@@H]2C[C@@H](O)CN12>>O=C1CCN(c2ccc(C(F)(F)F)cn2)C[C@@H]2C[C@@H](O)CN12,,CS(C)=O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20110312937A1,C[C@]1(c2ccccc2F)N=C(N)COC[C@@H]1F.O=[N+]([O-])O>>C[C@]1(c2cc([N+](=O)[O-])ccc2F)N=C(N)COC[C@@H]1F,,O=S(=O)(O)O,,[Na+].[OH-],,test
US06140354,Br[Mg]c1ccccc1.COc1ccc2c(c1)CCCC2=O>>COc1ccc2c(c1)CCC=C2c1ccccc1,,CCOCC,,[Cl-].[NH4+],,test
US20070213338A1,CS(=O)(=O)Cl.OCc1cccc(COc2nnc(Cl)c3ccccc23)n1>>CS(=O)(=O)OCc1cccc(COc2nnc(Cl)c3ccccc23)n1,,ClCCl,,CCN(CC)CC,,test
US05679696,COC(=O)c1ccc(OC(F)(F)F)c(OC2CCCC2)c1>>O=C(O)c1ccc(OC(F)(F)F)c(OC2CCCC2)c1,,CO,,O,O=C([O-])[O-].[K+].[K+],test
US20050059657A1,N#CCC(N)=O.ONC(Cl)c1ccsc1>>NC(=O)c1c(-c2ccsc2)noc1N,,C1CCOC1,,,,test
US04271163,NN.O=C(O)[C@@H]1C[C@@H]1C(=O)c1ccc(C2CCCCC2)cc1>>O=C1NN=C(c2ccc(C3CCCCC3)cc2)C2CC12,,CCO,,O,,test
US03978076,CCC1(C)NC(=O)NC1=O.ClCCCl>>CCC1(C)NC(=O)N(CCCl)C1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06229020B1,CCOC(=O)C(C)=Cc1cc(OC)c(OC)cc1[N+](=O)[O-]>>CCOC(=O)C(C)=Cc1cc(OC)c(OC)cc1N,[Fe],O,,CC(=O)O,,test
US20020058664A1,CCOC(=O)C[C@@H](Nc1nc(N(C)C2CCCCC2)ncc1Br)c1ccc(O[Si](C)(C)C(C)(C)C)cc1.OB(O)c1ccccc1F>>CCOC(=O)C[C@@H](Nc1nc(N(C)C2CCCCC2)ncc1-c1ccccc1F)c1ccc(O)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20090118305A1,Nc1ncc(-c2ccc(O)cc2)cc1-c1nc2cccnc2o1.OCCCN1CCCC1>>Nc1ncc(-c2ccc(OCCCN3CCCC3)cc2)cc1-c1nc2cccnc2o1,,CN(C)C=O,ClCCl,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05039333,CC(C)C1(C)N=C(c2ncc(C3OCCO3)cc2C(=O)O)NC1=O>>CC(C)C1(C)C(=O)N=C2c3ncc(C4OCCO4)cc3C(=O)N21,,Cc1ccccc1,,CC(=O)OC(C)=O,,test
US20140018384A1,COc1cc2c(cn1)c(=O)c(C(=O)c1ccc3ccccc3c1)cn2C(C)(C)CC(C)(C)C>>COc1cc2c(cn1)C(=O)C(C(=O)c1ccc3ccccc3c1)C=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050277619A1,CCOP(=O)(COCc1nc2c(Cl)ncnc2n1CC(C)(C)C)OCC.N>>CCOP(=O)(COCc1nc2c(N)ncnc2n1CC(C)(C)C)OCC,,C1CCOC1,CS(C)=O,,,test
US05095147,CC1(C(=O)Cl)CC1(F)F.N>>CC1(C(N)=O)CC1(F)F,,C1COCCO1,,,,test
US06177443B1,NCCc1cccs1.O=Cc1ccc([N+](=O)[O-])cc1>>O=[N+]([O-])c1ccc(C=NCCc2cccs2)cc1,,CCO,,CCN(CC)CC,,test
US20050288273A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCc2cnoc2-3)C(=O)O1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(=S)NC[C@H]1CN(c2ccc3c(c2)CCCc2cnoc2-3)C(=O)O1,,C1COCCO1,,,,test
US20160137643A1,NCC(F)(F)F.O=C(O)c1cnc2cncc(Br)c2c1>>O=C(NCC(F)(F)F)c1cnc2cncc(Br)c2c1,CN(C)C=O,ClCCl,,CCN(CC)CC,,test
US04855086,C#CCCCO.Cc1ccccc1I>>Cc1ccccc1C#CCCCO,,CCNCC,,,,test
US20090209529A1,Brc1cccc(Br)c1.CC(=O)c1ccc(OC(F)F)c(Cl)c1>>C=C(c1cccc(Br)c1)c1ccc(OC(F)F)c(Cl)c1,,C1CCOC1,,[Li]CCCC,,test
US20130072467A1,CC(C)(C)OC(=O)CNC1=NC(=O)SC1.O=CC1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1>>CC(C)(C)OC(=O)CNC1=NC(=O)S/C1=C\C1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1,,CC(C)O,,C1CC[NH2+]CC1.CC(=O)[O-],,test
US20110112089A1,CC(C)(C)OC(=O)N1CCC(C(N)=S)CC1.O=C(O)c1ccc(C(=O)CBr)cc1>>O=C(O)c1ccc(-c2csc(C3CCNCC3)n2)cc1,,C1CCOC1,,CCOCC,,test
US20130197217A1,CCOC(=O)C(=O)c1cccc(Cl)c1>>O=C(O)C(=O)c1cccc(Cl)c1,,C1CCOC1,CO,[Na+].[OH-],,test
US05637554,Cc1ccnc2c1C(=O)c1ccccc1-2>>Cc1ccnc2c1C(O)c1ccccc1-2,,CO,,[BH4-].[Na+],,test
US04865837,ClCc1ccccc1.c1nc[nH]n1>>c1ccc(Cn2cncn2)cc1,,CO,,C[O-].[Na+],,test
US20090181928A1,Brc1nccs1.O=Cc1ccc([N+](=O)[O-])c(OCc2ccccc2)c1>>O=[N+]([O-])c1ccc(C(O)c2nccs2)cc1OCc1ccccc1,,C1CCOC1,CCOCC,[Li]CCCC,[Cl-].[NH4+],test
US20110312904A1,C=C[C@H](O)C#CC#CC[C@H](O)[C@@H](O)CCCCCCC>>C=CC(O)C#CC#CC,,O,,ClC(Cl)Cl,,test
US04725608,NN1CC=CCC1.O=C=Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)NN1CC=CCC1,,C1COCCO1,O,Cl,[Na+].[OH-],test
US20120214732A1,C=C(C)C(=O)[C@H](Cc1ccc(CNC(=O)OC(C)(C)C)cc1)NC(=O)OCc1ccccc1>>C=C(C)[C@@H](O)[C@H](Cc1ccc(CNC(=O)OC(C)(C)C)cc1)NC(=O)OCc1ccccc1,,CO,,CC(=O)O,[BH4-].[Na+],test
US20080058327A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C(CNC(C)C)c1ccc(Cl)cc1>>COC(=O)C(CN(C(=O)OC(C)(C)C)C(C)C)c1ccc(Cl)cc1,CN(C)c1ccncc1,ClCCl,,,,test
US20090318373A1,CO[C@H]1[C@H](OC)O[C@@H]2[C@H](OC(=O)c3ccccc3)CO[C@H]12>>CO[C@H]1[C@H](OC)O[C@@H]2[C@H](O)CO[C@H]12,,CCOC(C)=O,CO,[Na+].[OH-],,test
US20160185778A1,C1CC(c2n[nH]c3c2CNCC3)C1.O=C=Nc1cccc(Cl)c1>>O=C(Nc1cccc(Cl)c1)N1CCc2[nH]nc(C3CCC3)c2C1,,ClCCl,,Cl,,test
US20050272669A1,C=CC(N)=O.NCc1ccccc1>>NC(=O)CCNCc1ccccc1,,CCO,,,,test
US20140107194A1,CC(C)C[C@H](N)C(=O)O[C@H]1c2ccccc2C[C@]1(Cc1ccc(C(=O)O)cc1)C1=Cc2ccccc2C1.NCCO>>CC(C)C[C@H](N)C(=O)O[C@H]1c2ccccc2C[C@]1(Cc1ccc(C(=O)NCCO)cc1)C1=Cc2ccccc2C1,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US04522763,COC(=O)Cl.N=C(N)Cc1ccccc1>>COC(=O)NC(=N)Cc1ccccc1,,ClCCCl,O,Cl,[K+].[OH-],test
US20100226881A1,CC(=O)OC(C)=O.O=Cc1cnn2ccc(O)cc12>>CC(=O)Oc1ccn2ncc(C=O)c2c1,,ClCCl,,CCN(CC)CC,,test
US04900752,CC(=O)NC1c2cc3nonc3cc2OC(C)(C)C1O>>CC(=O)NC1=CC(C)(C)Oc2cc3nonc3cc21,,O,,C1CCOC1,[H-].[Na+],test
US20040006058A1,CC(C)(C)OC(=O)N1CC(Oc2ccc(Nc3nc(N)c(C(=O)c4cccc(F)c4)s3)cc2)C1>>Nc1nc(Nc2ccc(OC3CNC3)cc2)sc1C(=O)c1cccc(F)c1,,CCOCC,Cl,,,test
US20080139548A1,CCOC(=O)c1cc2ccccc2n1CC#N>>N#CCn1c(C(=O)O)cc2ccccc21,,C1CCOC1,O,[Li]O,,test
US05536737,COc1ccc(OCC(O)[C@@H]2CCCN2C(=O)OC(C)(C)C)cc1.O=C(O)[C@@H]1CCCN1.O=C=NCc1ccccc1>>COc1ccc(OC(O)C[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)NCc2ccccc2)cc1,,CCN(CC)CC,,CN(C)C=O,Cl,test
US20040024045A1,COC(=O)[C@H](O)CNC(=O)c1ccc(CN(C(=O)OC(C)(C)C)c2ccc(C3CCCCC3)cc2)cc1>>COC(=O)[C@H](O)CNC(=O)c1ccc(CNc2ccc(C3CCCCC3)cc2)cc1,,CCOC(C)=O,,Cl,,test
US20040132769A1,BrBr.Cc1cc(F)c(Cl)c(N)c1F>>Cc1c(F)c(N)c(Cl)c(F)c1Br,,CO,,,,test
US20140336106A1,CC(C)(C)OC(=O)N[C@@H](CO)C(=O)O.COc1ccc([C@@H](O)[C@H](N)C(=O)OCc2ccccc2)cc1>>COc1ccc([C@@H](O)[C@H](NC(=O)[C@H](CO)NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050239786A1,CCCC[Sn](CCCC)(CCCC)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1C.O=C(c1ccccc1Cl)c1cccnc1Br>>Cc1c(-c2ncccc2C(=O)c2ccccc2Cl)nnn1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1,,CN(C)C=O,,,,test
US20160207883A1,BrCCOC1CCCCO1.OC1CCOC1>>C1CCC(OCCOC2CCOC2)OC1,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20140121198A1,O=[N+]([O-])c1cnc2ccsc2c1NC1CCCCC1>>Nc1cnc2ccsc2c1NC1CCCCC1,[Pd],CO,,,,test
US06303627B1,COc1ccc2cc(C3CCN(Cc4ccccc4)CC3)ccc2c1>>Oc1ccc2cc(C3CCN(Cc4ccccc4)CC3)ccc2c1,,CC(=O)O,,Br,[Na+].[OH-],test
US20080021022A1,N#C[Cu].O=C(c1cnoc1-c1ccc(I)cc1)N1CCC(c2ccccc2)C1>>N#Cc1ccc(-c2oncc2C(=O)N2CCC(c3ccccc3)C2)cc1,,CN1CCCC1=O,,,,test
US20060135773A1,COc1ccccc1S(=O)(=O)Cl.NCC12CC3CC(CC(C3)C1)C2>>COc1ccccc1S(N)(=O)=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160272604A1,BrC(Br)(Br)Br.OCCOCCOCCO>>OCCOCCOCCBr,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US06232310B1,CC(=O)Cl.N#CCSc1ccc(F)cc1N>>CC(=O)Nc1cc(F)ccc1SCC#N,,C1CCOC1,,c1ccncc1,,test
US05116862,C#C[Si](C)(C)C.ClCCCI>>C[Si](C)(C)C#CCCCCl,,C1CCOC1,,O,[Li]CCCC,test
US20010027196A1,COCCO.CS(=O)c1nc(N)nc(-c2ccco2)c1I>>COCCOc1nc(N)nc(-c2ccco2)c1I,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US05643920,O=C(CBr)c1ccc(Cl)cc1.O=C1CCCc2ncccc21>>O=C1CCc2c(-c3ccc(Cl)cc3)cn3cccc1c23,,Cc1ccccc1,,,,test
US20090286811A1,COc1cccc(C=O)c1OCC1CC1.Cc1nc2sc3ccccc3n2c(=O)c1-c1ccc(C(F)(F)F)cc1>>COc1cccc(/C=C/c2nc3sc4ccccc4n3c(=O)c2-c2ccc(C(F)(F)F)cc2)c1OCC1CC1,,CCO,,C,C[O-].[Na+],test
US20050176775A1,CC(=O)CC(O)=C1C(=O)OC(C)(C)OC1=O.Cc1ccccc1.Nc1cccc(Br)c1>>Cc1ccc(Br)cc1-n1c(C)cc(O)cc1=O,,CCOCC,Cc1ccccc1,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040063759A1,O=C(CCl)N1CCC(Oc2ccc(F)cc2)CC1.O=[N+]([O-])c1cc(Cl)ccc1O>>O=C(COc1ccc(Cl)cc1[N+](=O)[O-])N1CCC(Oc2ccc(F)cc2)CC1,,CCC(C)=O,,[I-].[K+],,test
US20120302610A1,CCOC(=O)CCNC(=O)c1ccc(-c2cc(C(F)(F)F)ccc2C=O)cn1.Nc1ccc(I)c(Cl)c1>>CCOC(=O)CCNC(=O)c1ccc(-c2cc(C(F)(F)F)ccc2CNc2ccc(I)c(Cl)c2)cn1,,CCOC(C)=O,ClCCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04885373,NC1CCc2cc3c(cc2C1)OCC3.O=C(Cl)CCCCl>>O=C(CCCCl)NC1CCc2cc3c(cc2C1)OCC3,,O,c1ccccc1,CCN(CC)CC,Cl,test
US05527816,O=S(Cl)Cl.OCCOc1ccccc1>>ClCCOc1ccccc1,,c1ccncc1,,Cc1ccccc1,,test
US20110046093A1,CN(C)C=O.COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC1(CC1)C(=O)N2C.NC1CCC(N2CCCN(Cc3ccccc3)CC2)CC1>>COc1cc(C(=O)N[C@@H]2CC[C@@H](N3CCOCC3)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC1(CC1)C(=O)N2C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US04154740,CON.O=C=NC1CCCc2ccsc21>>CONC(=O)NC1CCCc2ccsc21,,ClCCl,,CCN(CC)CC,Cl,test
US20160168139A1,O=[N+]([O-])c1cccc(O)c1Sc1cccc(Cl)c1Cl>>O=[N+]([O-])c1cccc2c1Sc1cccc(Cl)c1O2,,CN1CCCC1=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100210680A1,CB1OB(C)OB(C)O1.Clc1c(Br)ccc2c1CO[C@H]1CCN(Cc3ccccc3)C[C@H]21>>Cc1ccc2c(c1Cl)CO[C@H]1CCN(Cc3ccccc3)C[C@H]21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US04091109,CCCSc1cc(O)ccc1C.FC(F)(F)c1cccc(Br)c1>>CCCSc1cc(Oc2cccc(C(F)(F)F)c2)ccc1C,,CC(=O)N(C)C,,O,[K+].[OH-],test
US06855722B2,CO.Cc1cccc(OCCOCc2ccccc2)c1[N+](=O)[O-]>>c1ccc(COCCOc2ccc3[nH]ccc3c2)cc1,[Pd],CCOC(C)=O,CO,C1CCNC1,,test
US20120115909A1,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CCS3)nc1.O>>CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CCS3=O)nc1,,O,,CO,,test
US20080221110A1,CC(C)(C)OC(=O)NC1CCN(CC2Cn3c(=O)ccc4ccc(F)c2c43)CC1>>NC1CCN(CC2Cn3c(=O)ccc4ccc(F)c2c43)CC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20080241592A1,Brc1ccc(Br)cc1.O=C1OC(c2ccccc2)c2ccccc21>>BrC1(c2oc(-c3ccccc3)c3ccccc23)C=CC=CC1,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US05089485,CCCCCCCCCCCCC(O)c1coc([Si](C)(C)C)c1.O=C(Cl)CCCBr>>CCCCCCCCCCCCC(OC(=O)CCCBr)c1coc([Si](C)(C)C)c1,,C1CCOC1,CCCCC,[Li]C(C)(C)C,,test
US20050085470A1,CCC1(CC)OC(=O)Nc2ccc([N+](=O)[O-])cc21.CI>>CCC1(CC)OC(=O)N(C)c2ccc([N+](=O)[O-])cc21,,CN(C)C=O,,[H-].[Na+],,test
US20040209881A1,COc1ccc(Nc2nc(Cl)nc(NC3CCCCCC3)n2)cc1Cl.OC1CCCNC1>>COc1ccc(Nc2nc(NC3CCCCCC3)nc(N3CCCC(O)C3)n2)cc1Cl,,c1ccccc1,,[Na+].[OH-],,test
US20090048258A1,Nc1nc(-c2ccccc2)c(Cc2ccccc2)s1.O=C(O)CCC(=O)c1ccc2c(c1)CCCC2>>O=C(CCC(=O)c1ccc2c(c1)CCCC2)Nc1nc(-c2ccccc2)c(Cc2ccccc2)s1,,CC#N,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20140349998A1,CCOC(=O)c1c[nH]c2ncnc(-c3cccc(N)c3)c12.O=S(=O)(Cl)CCCl>>C=CS(=O)(=O)Nc1cccc(-c2ncnc3[nH]cc(C(=O)OCC)c23)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20050124659A1,Nc1cc(F)ccc1NC1CCN(Cc2ccccc2)CC1.O=C(OC(=O)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)F>>Fc1ccc2c(c1)nc(C(F)(F)C(F)(F)F)n2C1CCN(Cc2ccccc2)CC1,,CCOC(C)=O,,N,,test
US05750213,C1CCOC1.C=CC(=O)O.CCOC(=O)N=NC(=O)[O-].OCCCCCCC(CCCCCCO)CCCCCCCOc1ccc(-c2cccc(F)c2F)cc1>>C=CC(=O)OCCCCCCC(CCCCCCCOc1ccc(-c2cccc(F)c2F)cc1)CCCCCCOC(=O)C=C,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20160039834A1,Cc1noc(C)c1-c1nc(-c2cc(O)ccc2C(F)(F)F)nc(Cl)c1C.c1ncc2c(n1)CNC2>>Cc1noc(C)c1-c1nc(-c2cc(O)ccc2C(F)(F)F)nc(N2Cc3cncnc3C2)c1C,,CS(C)=O,O,CCN(CC)CC,Cl,test
US05216003,COC(=O)c1cccc(C)c1[N+](=O)[O-].O=C1CCC(=O)N1Br>>COC(=O)c1cccc(CBr)c1[N+](=O)[O-],,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20100298343A1,CCOC(=O)C(Cc1ccccc1)c1c(SC(C)(C)C)c2cc(OC)ccc2n1C>>COc1ccc2c(c1)c(SC(C)(C)C)c(C(CO)Cc1ccccc1)n2C,,C1CCOC1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20130109678A1,Nc1ccc(-c2nc3cc(N4CCSCC4)ccc3[nH]2)cc1[N+](=O)[O-]>>Nc1ccc(-c2nc3cc(N4CCSCC4)ccc3[nH]2)cc1N,[Pd],CCOC(C)=O,CO,,,test
US20110263594A1,Nc1nc2ccc(Sc3nnc4ccc(-c5ccc(F)cc5)cn34)cc2s1.O=C(Cl)C1CC1>>O=C(Nc1nc2ccc(Sc3nnc4ccc(-c5ccc(F)cc5)cn34)cc2s1)C1CC1,,c1ccncc1,,,,test
US20110166163A1,COC(=O)CCCCCNc1ncnc2oc(Br)c(-c3ccc(OC)cc3)c12.OB(O)c1cccnc1F>>COC(=O)CCCCCNc1ncnc2oc(-c3cccnc3F)c(-c3ccc(OC)cc3)c12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20160221945A1,O=C(NCc1cc(Cl)nc(-c2ccc(C(F)(F)F)nc2)c1)[C@@H]1C[C@@H](F)CN1.O=S(=O)(Cl)c1ccc(F)cc1>>O=C(NCc1cc(Cl)nc(-c2ccc(C(F)(F)F)nc2)c1)[C@@H]1C[C@@H](F)CN1S(=O)(=O)c1ccc(F)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20080119518A1,COc1ccc(Br)cc1CC1COC(C)(C)O1.Oc1ccccn1>>COc1ccc(-n2ccccc2=O)cc1CC1COC(C)(C)O1,I[Cu]I,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20110003784A1,CNC(=O)C1CN(C(=O)OCc2ccccc2)CCN1C(=O)OC(C)(C)C>>CNC(=O)C1CNCCN1C(=O)OC(C)(C)C,,CO,,,,test
US20070197598A1,CCOC(=O)C(C)(O)C(C)C.N=C(N)N>>CC(C)C1(C)OC(N)=NC1=O,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20090181942A1,COc1cccc([C@H]2O[C@H](CCO)c3nnc(C(F)(F)F)n3-c3ccc(Cl)cc32)c1OC.CS(=O)(=O)Cl>>COc1cccc([C@H]2O[C@H](CCOS(C)(=O)=O)c3nnc(C(F)(F)F)n3-c3ccc(Cl)cc32)c1OC,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US05036107,C#CCCCO.C=O.CC(C)NC(C)C>>CC(C)N(CC#CCCCO)C(C)C,,C1COCCO1,,[K+].[OH-],,test
US05223499,CCCCC(=O)Nc1cc2nc[nH]c2nc1C>>Cc1nc2[nH]cnc2cc1N,,CCOC(C)=O,CO,Cl,O=C([O-])O.[Na+],test
US20040127574A1,NC(Cc1ccc(C(F)(F)F)c(F)c1)C(O)c1ccc(F)cc1.O=C(Cl)CCc1ccccc1>>O=C(CCc1ccccc1)NC(Cc1ccc(C(F)(F)F)c(F)c1)C(O)c1ccc(F)cc1,,CCOC(C)=O,O,O=C([O-])O.[Na+],,test
US20140350020A1,COC(=O)C(C)(C)c1nnc(-c2nn(Cc3ccc(F)cc3F)c3ncccc23)nc1O.N>>CC1(C)C(=O)Nc2nc(-c3nn(Cc4ccc(F)cc4F)c4ncccc34)nnc21,,CC#N,,O=P(Cl)(Cl)Cl,,test
US20120115844A1,COC(=O)c1ccc(Cl)nc1.Cc1nnn(-c2ccc(F)cc2)c1CO>>COC(=O)c1ccc(OCc2c(C)nnn2-c2ccc(F)cc2)nc1,,C1CCOC1,,O,[H-].[Na+],test
US20020165241A1,Fc1cnc(Cl)nc1.NCC1CCN(C(=O)OCc2ccc(F)cc2)CC1>>O=C(OCc1ccc(F)cc1)N1CCC(CNc2ncc(F)cn2)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US20120088755A1,Cc1nc(Cl)cc(Oc2cc(C)c3[nH]c(=O)oc3c2)n1.O=C1CC2(CCNCC2)c2cccnc2N1>>Cc1nc(Oc2cc(C)c3[nH]c(=O)oc3c2)cc(N2CCC3(CC2)CC(=O)Nc2ncccc23)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20050277630A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)OCCC(C(=O)c2ccccc2)C3=O)C(=O)O1.CNN>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)OCCc2cn(C)nc2-3)C(=O)O1,,CCO,,CCN(CC)CC,,test
US05741800,O=C(CCc1ccccc1)N1CCC(CCCl)CC1.c1c[nH]cn1>>O=C(CCc1ccccc1)N1CCC(CCn2ccnc2)CC1,,C1CCOC1,O,[Na+].[OH-],,test
US04804400,CC1=C(C)C(=O)OC1=O.Nc1cc(C(=O)O)ccc1F>>CC1=C(C)C(=O)N(c2cc(C(=O)O)ccc2F)C1=O,,CC(=O)O,,,,test
US20120053173A1,CCC(=O)c1oc2ccc(OCc3ccccc3)cc2c1C>>CCC(O)c1oc2ccc(OCc3ccccc3)cc2c1C,,C1CCOC1,CO,[BH4-].[Na+],,test
US20150336935A1,COc1cc(OC)cc(C(=O)[C@H]2[C@H](C)[C@@H](CNC(=O)c3ccccc3)C[C@H]3C(C)(C)CCC[C@]23C)c1>>C[C@@H]1[C@@H](CNC(=O)c2ccccc2)C[C@H]2C(C)(C)CCC[C@]2(C)[C@H]1C(=O)c1cc(O)cc(O)c1,,ClCCl,,BrB(Br)Br,,test
US20090227640A1,Fc1ccc(OCC#Cc2ccc(C(F)(F)F)cc2)c(CBr)c1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>Fc1ccc(OCC#Cc2ccc(C(F)(F)F)cc2)c(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c1.[Br-],,ClCCl,,,,test
US07091231B2,COC(=O)COc1cccc(CO)c1.II>>COC(=O)COc1cccc(CI)c1,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090291950A1,COc1ccc2c(c1OC1CCCC1)OCCC2=O.NO>>COc1ccc2c(c1OC1CCCC1)OCCC2=NO,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080318976A1,CC(=O)OC(C)=O.C[Mg]Cl.N#Cc1ncc(Br)cc1F>>C=C(NC(C)=O)c1ncc(Br)cc1F,,Cc1ccccc1,,,,test
US20100190826A1,CCOC(=O)c1cccc(I)c1.N#Cc1ccc2[nH]ccc2c1>>CCOC(=O)c1cccc(-n2ccc3cc(C#N)ccc32)c1,[Cu]I,C1COCCO1,CCOC(C)=O,CN[C@@H]1CCCC[C@H]1NC,O=C([O-])[O-].[K+].[K+],test
US20110172187A1,O=[N+]([O-])c1cccc(CBr)c1.[C-]#N>>N#CCc1cccc([N+](=O)[O-])c1,,CN(C)C=O,,O,,test
US20150045359A1,CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(C(=O)O)cc2)C1.N[C@@H](CO)c1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(C(=O)N[C@@H](CO)c3ccc(F)cc3)cc2)C1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US20140249133A1,CCOC(=O)/N=N/C(=O)OCC.CCOc1cc(F)c(Cn2nc(-c3ncc(OCCS(C)=O)c(Nc4ccncc4)n3)c3ccccc32)c(F)c1>>CCOc1cc(F)c(Cn2nc(-c3ncc(OCCS(C)(=O)=O)c(Nc4ccncc4)n3)c3ccccc32)c(F)c1,,C1CCOC1,,OO,,test
US20100120761A1,Brc1cn[nH]c1.CN(C)S(=O)(=O)Cl>>CN(C)S(=O)(=O)n1cc(Br)cn1,,CC#N,,C1CN2CCN1CC2,,test
US20040229949A1,COC(=O)C(Cc1ccc(OCCc2ccc(NC(=O)OC(C)(C)C)cc2)cc1)OCC(F)(F)F>>CC(C)(C)OC(=O)Nc1ccc(CCOc2ccc(CC(OCC(F)(F)F)C(=O)O)cc2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20030195232A1,OCCCc1cccnc1.Oc1cccnc1Sc1cccc(Br)c1>>Brc1cccc(Sc2ncccc2OCCCc2cccnc2)c1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04492692,CCN1CCN(C(=O)Cl)C(=O)C1=O.NCCCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)n1>>CCN1CCN(C(=O)NCCCc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c(F)n2)C(=O)C1=O,CN(C)c1ccncc1,ClCCl,,,,test
US20060111375A1,COc1cc2nccc(Cl)c2cc1OC.O=C(c1ccccc1)c1cc(Cl)ccc1O>>COc1cc2nccc(Oc3ccc(Cl)cc3C(=O)c3ccccc3)c2cc1OC.Cl,,ClC(Cl)Cl,,[Na+].[OH-],,test
US20160185752A1,Cl.FC(F)(F)c1ccc(-c2cccnc2)cc1>>Cl.FC(F)(F)c1ccc(C2CCCNC2)cc1,O=[Pt]=O,CCO,,,,test
US05756769,C#CCOS(C)(=O)=O.N.O=Cc1ccccc1Cl>>C#CCN=Cc1ccccc1Cl,,Cc1ccccc1,,,,test
US20070259871A1,CC(C)c1cc(C(=O)N2Cc3ccc(OCCCNC(=O)OC(C)(C)C)cc3C2)c(O)cc1O.Cl>>CC(C)c1cc(C(=O)N2Cc3ccc(OCCCN)cc3C2)c(O)cc1O.Cl,,CCOC(C)=O,,,,test
US20110166139A1,CON(C)C(=O)c1ccccc1N.N#Cc1cnc(Cl)cc1Cl>>CON(C)C(=O)c1ccccc1Nc1cc(Cl)ncc1C#N,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20020173664A1,CCCCCCCCCC(=O)N1C(=O)OC(=O)[C@@H]1C.Cc1ccc([C@H](C)N)cc1>>CCCCCCCCCC(=O)N[C@@H](C)C(=O)N[C@@H](C)c1ccc(C)cc1,,C1CCOC1,,CN1CCOCC1,,test
US20160122331A1,COC(=O)c1cccc([C@H]2C[C@@H](NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)CCO2)c1>>O=C(O)c1cccc(C2CC(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)CCO2)c1,,CO,,[Na+].[OH-],,test
US20090291940A1,CC(C)(C)OC(=O)N1CCN(c2nc(Cl)nc3ccccc23)CC1.N[C@H]1CCN(Cc2ccccc2)C1>>CC(C)(C)OC(=O)N1CCN(c2nc(N[C@H]3CCN(Cc4ccccc4)C3)nc3ccccc23)CC1,,CC(C)O,,CCN(CC)CC,,test
US20140275111A1,CCOC(=O)C(C)(C)Cc1ccc(N)cc1C(F)(F)F>>CC(C)(CO)Cc1ccc(N)cc1C(F)(F)F,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20050137212A1,Brc1ccc(-c2coc(C3CC3)n2)cc1.N#C[Cu]C#N>>N#Cc1ccc(-c2coc(C3CC3)n2)cc1,,CN1CCCC1=O,,[C-]#N.[Na+],,test
US05120748,ClCCCBr.Sc1ccncc1>>ClCCCSc1ccncc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US03962321,CCCCCC/C=C/C=O>>CCCCCC/C=C/CO,,CCOCC,,CCOC(C)=O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20140088075A1,CC(=O)Cl.CC(C)n1c(=O)c(-c2cc(NC(=O)Nc3cccc(F)c3)c(F)cc2Cl)cc2cnc(N)cc21>>CC(=O)Nc1cc2c(cn1)cc(-c1cc(NC(=O)Nc3cccc(F)c3)c(F)cc1Cl)c(=O)n2C(C)C,,c1ccncc1,,,,test
US05658922,CC(=O)[C@H]1CC[C@H]2[C@@H]3[C@@H](C)C[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@@]21C.CI.[Li]C>>C[C@H]1C[C@H]2N(C)C(=O)C=C[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@H]3C(C)(C)O)[C@H]12,,C1CCOC1,,CCOCC,[Cl-].[NH4+],test
US20150291593A1,Cc1cc2nccn2c(=O)n1-c1ccccc1.O=C1CCC(=O)N1Cl>>Cc1cc2ncc(Cl)n2c(=O)n1-c1ccccc1,,CN(C)C=O,,O,,test
US20060014947A1,C[C@H]1COc2c(ccc(F)c2F)N1>>C[C@H]1COc2c(ccc(F)c2F)N1,,CCOC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20150119404A1,CN1CC[C@](CC#Cc2nccc(-c3ccc(C(F)(F)F)cc3)n2)(NC(=O)OC(C)(C)C)C1=O>>CN1CC[C@@](N)(CC#Cc2nccc(-c3ccc(C(F)(F)F)cc3)n2)C1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150191452A1,CC(C)(C)OC(=O)Oc1ccc([C@@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2O)cc1>>CC(C)(C)OC(=O)N1CC[C@@H](c2ccc(O)cc2)[C@H](O)C1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20110213143A1,CC(C)(C)c1oc(=O)oc1COC(=O)Oc1ccc([N+](=O)[O-])cc1.NCCC[C@@H](Cc1ncn2c1CCc1ccccc1-2)C(=O)O>>CC(C)(C)c1oc(=O)oc1COC(=O)NCCC[C@@H](Cc1ncn2c1CCc1ccccc1-2)C(=O)O,,CN(C)C=O,,Cc1ccccc1,,test
US20120122840A1,Clc1nc(Cl)c2[nH]cnc2n1.SC1CCCCC1>>Clc1nc(SC2CCCCC2)c2nc[nH]c2n1,,CCO,,CCN(CC)CC,,test
US20120172599A1,CC1=C(C#N)C(=C(C#N)C#N)OC1(C)C.CCCCN(CCCC)c1ccc(C=Cc2ccc(C=O)cc2)cc1>>CCCCN(CCCC)c1ccc(C=Cc2ccc(C=CC3=C(C#N)C(=C(C#N)C#N)OC3(C)C)cc2)cc1,,C1CCOC1,CCO,C,O=C[O-].[NH4+],test
US20150126490A1,II.OCC1(c2ccc(F)nc2)CCOCC1>>Fc1ccc(C2(CI)CCOCC2)cn1,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160083370A1,Cc1cc(C)nc(N2CCNCC2)n1.Cc1ccc(S(=O)(=O)OCCCc2c[nH]c3ccccc23)cc1>>Cc1cc(C)nc(N2CCN(CCCc3c[nH]c4ccccc34)CC2)n1,,CC#N,,[I-].[K+],,test
US20060276475A1,Nc1nc(NCC2CCCN2)nc2nc(-c3ccco3)nn12.O=Cc1c(Cl)cccc1Cl>>Nc1nc(NCC2CCCN2Cc2c(Cl)cccc2Cl)nc2nc(-c3ccco3)nn12,,CC(=O)O,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US06239151B1,CC(C)CNNC(=O)[C@H](CC(C)C)[C@H](C/C=C/c1ccccc1)C(=O)NOC1CCCCO1.O=C(NC1(C(=O)O)CCCC1)OCC1c2ccccc2-c2ccccc21>>CC(C)C[C@@H](C(=O)NN(CC(C)C)C(=O)C1(NC(=O)OCC2c3ccccc3-c3ccccc32)CCCC1)[C@H](C/C=C/c1ccccc1)C(=O)NOC1CCCCO1,,CCOC(C)=O,ClCCl,c1ccncc1,,test
US04432993,COC(=O)/C=C/c1ccc(CC(C)=O)cc1.NCC(O)c1cc2ccccc2o1>>COC(=O)/C=C/c1ccc(CC(C)NCC(O)c2cc3ccccc3o2)cc1,,O,,,,test
US20150299190A1,CC(=O)c1cc([N+](=O)[O-])ccc1Cl.Nc1ncccc1C=O>>O=[N+]([O-])c1ccc(Cl)c(-c2ccc3cccnc3n2)c1,,CCO,,[Na+].[OH-],,test
US05387714,CNC(=O)/C(=N/OC)c1ccccc1CBr.Cc1ccc(C)c(O)c1>>CNC(=O)/C(=N/OC)c1ccccc1COc1cc(C)ccc1C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20160068489A1,Cc1nc(N)c(C)c(C)c1OCc1ccccc1.O=C(Cl)Cc1ccc(Cl)cc1>>Cc1nc(NC(=O)Cc2ccc(Cl)cc2)c(C)c(C)c1OCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US06156787,CC1(C)CC(=O)c2c(S(C)(=O)=O)sc(C(=O)N3CCCC3)c2C1.FC(F)(F)CS>>CC1(C)CC(=O)c2c(SCC(F)(F)F)sc(C(=O)N3CCCC3)c2C1,,CCO,,[Na+].[OH-],,test
US20150011532A1,CCOC(=O)c1cnc(Cl)cc1NC1CCC1>>CC(C)Nc1cc(Cl)ncc1CO,,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US04483833,CC(=O)CCC(C)=O.NCCOCCO>>Cc1ccc(C)n1CCOCCO,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,,,test
US20090270365A1,C1CCNCC1.CCOC(=O)c1ccc(-c2ccccc2)c(CCBr)c1>>CCOC(=O)c1ccc(-c2ccccc2)c(CN2CCCCC2)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040110789A1,COc1cccc(N)c1.O=C1CN2CCC1CC2>>COc1cccc(NC2CN3CCC2CC3)c1,,CCO,,[BH4-].[Na+],,test
US20130184463A1,CC(C)CO.COC(=O)c1cc(O[Si](C)(C)C(C)(C)C)ccc1O>>COC(=O)c1cc(O[Si](C)(C)C(C)(C)C)ccc1OCC(C)C,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140256740A1,O=C(Cc1ccc(O)cc1)NC(c1ccccc1)c1ccc(Cl)cc1.OCc1cnco1>>O=C(Cc1ccc(OCc2cnco2)cc1)NC(c1ccccc1)c1ccc(Cl)cc1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100249099A1,COc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCN(S(=O)(=O)CCN(C)C)CC2)n1.Cl>>COc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCN(S(=O)(=O)CCN(C)C)CC2)n1.Cl,,CO,,,,test
US20040110757A1,N=C(N)c1ccccc1.O=C(/C=C/c1cccc([N+](=O)[O-])c1)c1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(-c2cc(-c3cccc([N+](=O)[O-])c3)nc(-c3ccccc3)n2)c1,,,,Cl,[K+].[OH-],test
US20160120841A1,CON=C1CC(c2cccc(C(=O)OC)c2)Oc2ncccc21>>COC(=O)c1cccc(C2CC(N)c3cccnc3O2)c1,[Ni],O,,CO,,test
US20140107073A1,CC(=O)CCl.CN(C)/C=N/c1ccc(Br)cn1>>CC(=O)c1cnc2ccc(Br)cn12,,CC(C)O,O,O=C([O-])O.[Na+],,test
US20070197507A1,COC(=O)N1CCNCC1.O=[N+]([O-])c1cccc2c1CCC2Cl>>COC(=O)N1CCN(C2CCc3c2cccc3[N+](=O)[O-])CC1,,CC#N,CCOC(C)=O,CCN(C(C)C)C(C)C,Cl,test
US20070111988A1,COc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc4c(c3)COC4=O)sc2c1.Cl>>COc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc4c(c3)COC4=O)sc2c1.Cl,,ClCCl,,CCOCC,,test
US20080009486A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C1(Oc2ccc(Cl)cc2/C=C2\C(=O)Nc3cc(Cl)ccc32)CCC1>>COC(=O)C1(Oc2ccc(Cl)cc2C=C2C(=O)N(C(=O)OC(C)(C)C)c3cc(Cl)ccc32)CCC1,CN(C)c1ccncc1,ClCCl,,,,test
US20130313129A1,O=S(=O)(O)O.O=S(=O)([O-])OOS(=O)(=O)[O-].[NH4+].[NH4+]>>O=S(=O)(O)O.O=S(=O)([O-])OOS(=O)(=O)[O-].[NH4+].[NH4+],,O,,,,test
US20040014755A1,COC(CN(Cc1ccsc1)S(=O)(=O)c1ccc(C)cc1)OC>>c1cc2sccc2cn1,,C1COCCO1,,Cl,ClCCl,test
US20050014806A1,CC(=O)NCc1cc(-c2ccc(-n3ccnc3)c(F)c2)no1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(=S)NCc1cc(-c2ccc(-n3ccnc3)c(F)c2)no1,,C1COCCO1,,,,test
US20120088748A1,CC(C)(C)OC(=O)N1CCO[C@@H](C(=O)O)[C@H](c2ccc(Cl)c(Cl)c2)C1.CI>>COC(=O)[C@@H]1OCCN(C(=O)OC(C)(C)C)C[C@H]1c1ccc(Cl)c(Cl)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120010190A1,Cn1cc(C(=O)CC(c2ccc(C(=O)O)c(F)c2)c2ccccc2Cl)ccc1=O.NCC(F)(F)F>>Cn1cc(C(=O)CC(c2ccc(C(=O)NCC(F)(F)F)c(F)c2)c2ccccc2Cl)ccc1=O,,C1CCOC1,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US05885986,CCCN(CCC)Cc1cnc(-c2ncn3c2[C@@H]2CCN2C(=O)c2ccccc2-3)o1.Cl>>CCCN(CCC)Cc1cnc(-c2ncn3c2[C@@H]2CCN2C(=O)c2ccccc2-3)o1.Cl,,CCOC(C)=O,,,,test
US20130252937A1,BrCC1CCOCC1.COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(O)cc5C)ccc(F)c43)ccc21>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(OCC6CCOCC6)cc5C)ccc(F)c43)ccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090312323A1,CC(C)c1ccc(N)cc1.CCOC(=O)c1cc(Cl)ccc1CBr>>CC(C)c1ccc(N2Cc3ccc(Cl)cc3C2=O)cc1,,CCO,,C,C[O-].[Na+],test
US20110207702A1,Nc1ccc2c(c1)B(O)OC2.O=C(Cl)c1cccs1>>O=C(Nc1ccc2c(c1)B(O)OC2)c1cccs1,,ClCCl,,CCN(CC)CC,,test
US04207322,CNC.Clc1ccc2c(n1)C(c1ccccc1Cl)=NCc1nncn1-2>>CN(C)c1ccc2c(n1)C(c1ccccc1Cl)=NCc1nncn1-2,,CO,,CCO,,test
US20040010037A1,CI.C[C@H]1CN(c2ccc(C#N)c(C(F)(F)F)c2)[C@H](C)CN1C(=O)Nc1ccc(F)cc1>>C[C@H]1CN(c2ccc(C#N)c(C(F)(F)F)c2)[C@H](C)CN1C(=O)N(C)c1ccc(F)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20100267911A1,CC(C)=O.CC(C)[Si](OS(=O)(=O)C(F)(F)F)(OS(=O)(=O)C(F)(F)F)C(C)C.CCOC(C)=O.O=C=O.[Li]CCCC>>CCOC(=O)C[Si](CC(=O)OCC)(C(C)C)C(C)C,,C1CCOC1,,CC(C)NC(C)C,,test
US20110178130A1,CC(C)(C)OC(=O)Nc1ccc(C[C@H](N)C(=O)OC(C)(C)C)cn1.CC(C)[C@H]1COCCCCOc2ccc(cc2)C[C@@H](N)C(=O)N1.O=C(n1ccnc1)n1ccnc1>>CC(C)[C@H]1COCCCCOc2ccc(cc2)C[C@@H](NC(=O)N[C@@H](Cc2ccc(NC(=O)OC(C)(C)C)nc2)C(=O)OC(C)(C)C)C(=O)N1,,CN(C)C=O,,CCN(CC)CC,,test
US20060025395A1,COc1ccc(C2OC[C@H](C)[C@@H]([C@@H](C)[C@@H](CC[C@H](C)C[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)/C=C\[C@H](C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](C)/C=C/COC(c3ccccc3)(c3ccccc3)c3ccccc3)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O2)cc1>>COc1ccc(CO[C@@H]([C@@H](C)CO)[C@@H](C)[C@@H](CC[C@H](C)C[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)/C=C\[C@H](C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](C)/C=C/COC(c2ccccc2)(c2ccccc2)c2ccccc2)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)cc1,,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US20120004166A1,CC(O)CCO.Oc1ccc(C(F)(F)F)cc1>>CC(CCO)Oc1ccc(C(F)(F)F)cc1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080113978A1,CCC(CC)c1cc(C)nn2c(-c3sc(Br)cc3C)c(C)nc12.CON(C)C(=O)c1ccccc1>>CCC(CC)c1cc(C)nn2c(-c3sc(C(=O)c4ccccc4)cc3C)c(C)nc12,,CCOC(C)=O,,C1CCOC1,[Li]CCCC,test
US20050256201A1,CS(=O)(=O)Cl.NS(=O)(=O)c1cccc(CCCCO)c1>>CS(=O)(=O)OCCCCc1cccc(S(N)(=O)=O)c1,,C1CCOC1,,CCN(CC)CC,,test
US04983586,CC(O)CN.O=C(O)c1cccnc1>>CC(O)CNC(=O)c1cccnc1,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US20140011799A1,CC1(C)CO1.O=c1ccc(Br)c[nH]1>>CC(C)(O)Cn1cc(Br)ccc1=O,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US05998436,CC(C)(C)N.Fc1nc(F)c(Cl)c(Br)c1F>>CC(C)(C)Nc1nc(F)c(Cl)c(Br)c1F,,CC#N,,,,test
US20030171584A1,Cn1c(=O)c(Oc2c(Cl)cccc2Cl)cc2cnc(S(C)(=O)=O)nc21.Nc1ccc(F)cc1>>Cn1c(=O)c(Oc2c(Cl)cccc2Cl)cc2cnc(Nc3ccc(F)cc3)nc21,,CN1CCCC1=O,,CO,,test
US20060089394A1,ClCc1ccccc1.O=Cc1ccc(O)c(F)c1>>O=Cc1ccc(OCc2ccccc2)c(F)c1,,CC#N,,,,test
US20080108608A1,C#Cc1cccc(N)c1.Clc1ncc(Br)cn1>>Nc1cccc(C#Cc2cnc(Cl)nc2)c1,[Pd],CCN(C(C)C)C(C)C,,,,test
US20020193596A1,COC(=O)c1ccc(CO)cc1-c1ccccc1C>>Cc1ccccc1-c1cc(CO)ccc1C(=O)O,,CCO,,[Na+].[OH-],,test
US20020032186A1,C1CCOC1.CCOC(=O)C1(S(=O)(=O)c2ccc(OC)cc2)CCN(Cc2cccc(OC)c2)CC1>>CCCCOc1ccc(S(=O)(=O)C2(C(=O)O)CCN(Cc3cccc(OC)c3)CC2)cc1,,[Na+],[OH-],CO,,test
US20030069434A1,CC(=O)O[C@@H]1C[C@]2(C)C(=O)CC[C@H]2[C@H]2[C@H]1[C@H]1CCC(=O)C=C1C[C@H]2CCCCCCCCCO.ClC(Cl)(Cl)Cl>>CC(=O)O[C@@H]1C[C@]2(C)C(=O)CC[C@H]2[C@H]2[C@H]1[C@H]1CCC(=O)C=C1C[C@H]2CCCCCCCCCCl,,CC#N,ClCCl,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04370497,COc1ccc([Te](=O)c2ccc(OC)cc2)cc1.Oc1ccc(O)cc1>>COc1ccc([Te]c2ccc(OC)cc2)cc1.O=C1C=CC(=O)C=C1,,ClC(Cl)Cl,,,,test
US20120202785A1,O=[N+]([O-])c1ccc(F)cc1Nc1ccc(F)nc1>>Nc1ccc(F)cc1Nc1ccc(F)nc1,,CCOC(C)=O,,,,test
US20120108596A1,Cc1cc(NC2=NC[C@@]3(CN4CCC3CC4)O2)ncc1Cl.O=C(OO)c1cccc(Cl)c1>>Cc1cc(NC2=NC[C@@]3(C[N+]4([O-])CCC3CC4)O2)ncc1Cl,,C1CCOC1,,,,test
US20100286145A1,COCc1cc(C(C)C)nc(N)n1>>CC(C)c1cc(CO)nc(N)n1,,ClCCl,,BrB(Br)Br,,test
US06211170B1,NCc1ccncc1.O=C(Cl)Oc1ccccc1>>O=C(NCc1ccncc1)Oc1ccccc1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20070213348A1,COC(=O)Cc1ccc(C(=C2CC(C)(C)CC(C)(C)C2)c2ccc(O)cc2)cc1>>CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(CC(=O)O)cc2)CC(C)(C)C1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20050245554A1,CC(=O)OC(C)=O.Nc1nc(Oc2ccc(F)c(F)c2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1>>CC(=O)Nc1nc(Oc2ccc(F)c(F)c2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1,CN(C)c1ccncc1,,,,,test
US04894385,COC(=O)c1ccc(S)cc1.Cc1ccccc1C(Cl)Cn1ccnc1>>COC(=O)c1ccc(SC(Cn2ccnc2)c2ccccc2C)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20080312208A1,NS(=O)(=O)Cc1ccccn1.O=C(OO)c1cccc(Cl)c1>>NS(=O)(=O)Cc1cccc[n+]1[O-],,ClCCl,,,,test
US03956325,CN1CNC(=O)C(c2ccccc2)(c2ccccn2)C1.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CN1CNC(=S)C(c2ccccc2)(c2ccccn2)C1,,c1ccccc1,,O,,test
US20090270374A1,COc1cc(=O)n(CCN2CCC(NC(=O)OC(C)(C)C)CC2)c2cc(F)ccc12>>COc1cc(=O)n(CCN2CCC(N)CC2)c2cc(F)ccc12,,C1COCCO1,,Cl,,test
US20040198790A1,CN1CCN(C(=O)CCC(=O)O)CC1.C[C@@H](S[C@H]1CO[C@H](/C=C/C=C/c2ccc(C#N)cc2F)OC1)[C@@](Cn1cncn1)(OC(=O)c1cc(C#N)ccc1CO)c1ccc(F)cc1F>>C[C@@H](S[C@H]1CO[C@H](/C=C/C=C/c2ccc(C#N)cc2F)OC1)[C@@](Cn1cncn1)(OC(=O)c1cc(C#N)ccc1COC(=O)CCC(=O)N1CCN(C)CC1)c1ccc(F)cc1F,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20080306040A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(CC(=O)O)Cc1cccc(Br)c1>>CC(C)(C)OC(=O)NC(CC(=O)O)Cc1cccc(Br)c1,,CO,O,Cl,[Na+].[OH-],test
US20130131040A1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1N.N#Cc1ncc(Cl)nc1Cl>>CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1cnc(C#N)c(Cl)n1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,O,test
US20120028951A1,CN(C)C=CC(=O)c1nn(-c2ccc(OC(F)F)cc2)ccc1=O.NNc1ccccc1>>O=c1ccn(-c2ccc(OC(F)F)cc2)nc1-c1ccnn1-c1ccccc1,,CO,,,,test
US20160068531A1,O=S(=O)(c1ccccc1)n1c(CO)cc2nc(Cl)ccc21.O=S(Cl)Cl>>O=S(=O)(c1ccccc1)n1c(CCl)cc2nc(Cl)ccc21,,ClCCl,,,,test
US20120252801A1,CCN1CC(C)(C)OC(=O)C1CC(=O)O.NC1CCCCC1>>CCN1CC(C)(C)OC(=O)C1CC(=O)NC1CCCCC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060074115A1,CC(C)=O.ClCCl.Oc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1.Oc1ccc2c(-c3ccc(Br)cc3)nsc2c1>>OC(c1ccc(OCCCOc2ccc3c(-c4ccc(Br)cc4)nsc3c2)cc1)(C(F)(F)F)C(F)(F)F,,ClCCl,,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US04232010,Cc1ccc(-c2nc3ccccc3s2)nc1.O=C1CCC(=O)N1Br>>BrCc1ccc(-c2nc3ccccc3s2)nc1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US04788206,COc1ccccc1C(O)(CC#N)c1ccccc1OC>>COc1ccccc1C(=CC#N)c1ccccc1OC,,c1ccncc1,,O=S(Cl)Cl,,test
US20070249620A1,O=C(O)Cc1ccc(O)c(Cl)c1>>OCCc1ccc(O)c(Cl)c1,,C1CCOC1,CCCCCC,B,CSC,test
US20130059834A1,CN(C)CCCn1nc(-c2cnc3c(n2)c(C(=O)NC(C)(C)CO[Si](C)(C)C(C)(C)C)cn3C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(OC(F)F)ccc21>>CN(C)CCCn1nc(-c2cnc3[nH]cc(C(=O)NC(C)(C)CO)c3n2)c2cc(OC(F)F)ccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150045368A1,CC1(C)OC(=O)N(c2ccc(I)cc2)[C@H]1c1ccccc1.OB(O)c1cc(Br)cnc1F>>CC1(C)OC(=O)N(c2ccc(-c3cc(Br)cnc3F)cc2)[C@H]1c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US04927822,CC(=O)SCCC(=O)N1N=C(c2ccc(C(F)(F)F)cc2)SC1C(=O)OCc1ccccc1>>O=C(O)C1SC(c2ccc(C(F)(F)F)cc2)=NN1C(=O)CCS,,CO,O,CC(=O)O,[K+].[OH-],test
US20040235822A1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4cncn4CCOC(C)=O)cc2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4cncn4CCOC(C)=O)cc2)CCN3CC(C)C)cc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20040152690A1,C[Si](C)(C)CCOCCl.FC(F)(F)c1cc2nc(N3CCN(c4ncccc4C(F)(F)F)CC3)[nH]c2cc1Br>>C[Si](C)(C)CCOCn1c(N2CCN(c3ncccc3C(F)(F)F)CC2)nc2cc(Br)c(C(F)(F)F)cc21,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20060154930A1,FC(F)(F)c1ccnnc1-c1cnnc(Cl)c1.NN>>NNc1cc(-c2nnccc2C(F)(F)F)cnn1,,C1CCOC1,CC(C)O,O,,test
US20080051418A1,CCOC(=O)CCc1cc(OC(C)C)n[nH]1.Fc1cc(Cl)ccc1CBr>>CCOC(=O)CCc1cc(OC(C)C)nn1Cc1ccc(Cl)cc1F,,CN(C)C=O,,Cl,[H-].[Na+],test
US20050004164A1,CCOC(=O)C(C#N)=Cc1ccccc1OC.COc1ccccc1[Mg]Br>>CCOC(=O)C(C#N)C(c1ccccc1OC)c1ccccc1OC,,C1CCOC1,,,,test
US20080167377A1,CCOC(=O)C(C(=O)OCc1ccccc1)c1ccc([N+](=O)[O-])cc1F>>CCOC(=O)Cc1ccc(N)cc1F,[Pd],CCO,,O=C[O-].[NH4+],,test
US03959309,CN(C)C1CCc2[nH]c3ccc([N+](=O)[O-])cc3c2C1>>CN(C)C1CCc2[nH]c3ccc(N)cc3c2C1,[Ni],CCO,,[H][H],,test
US07652057B2,CC#CC(=O)OC.NNc1ccccn1>>Cc1cc(=O)[nH]n1-c1ccccn1,,CC(C)(C)O,O,CC(C)(C)[O-].[K+],,test
US20080045507A1,CC(C)N1CCN(C(=O)c2ccc(C=O)cc2)CC1.CC(C)[Mg]Br>>CC(C)C(O)c1ccc(C(=O)N2CCN(C(C)C)CC2)cc1,,C1CCOC1,,,,test
US20160200704A1,COC(=O)c1ccc2ncc(Br)cc2c1>>OCc1ccc2ncc(Br)cc2c1,,C1CCOC1,,,,test
US20070232627A1,O=C(Nc1ccc(F)c([N+](=O)[O-])c1)c1ccco1.Oc1ccc(S)cc1>>O=C(Nc1ccc(Sc2ccc(O)cc2)c([N+](=O)[O-])c1)c1ccco1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20080293770A1,CI.O=[N+]([O-])c1cc(Cl)c(O)cc1F>>COc1cc(F)c([N+](=O)[O-])cc1Cl,,CCOCC,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080214614A1,CC(C)(C)C(=O)n1ncc2cc(NC3CCCNC3)ccc21.CSc1ccc(C=O)cc1>>CSc1ccc(CN2CCCC(Nc3ccc4c(cnn4C(=O)C(C)(C)C)c3)C2)cc1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100041717A1,N#CC(Cc1ccccc1)(c1cc(F)cc(C(F)(F)F)c1)c1ccc(F)cn1>>NCC(Cc1ccccc1)(c1cc(F)cc(C(F)(F)F)c1)c1ccc(F)cn1,,CO,ClCCl,[BH4-].[Na+],,test
US20100121074A1,C1CCNC1.CN1CCN(C)C1=O.O=P(Cl)(Cl)Cl>>CN1CC[NH+](C)C1N1CCCC1.[Cl-],,Cc1ccccc1,ClCCl,CCN(CC)CC,,test
US20040147561A1,Cc1[nH]c(=O)c(-c2csc(-c3ccncc3)n2)cc1CO.c1ccncc1>>Cc1[nH]c(=O)c(-c2csc(-c3ccncc3)n2)cc1CN1CC=CCC1,,c1ccncc1,,CS(=O)(=O)Cl,,test
US20100041714A1,CC(C)(C)OC(=O)COc1cccc2c1CCCC2N.O=S(=O)(Cl)c1ccc(-c2ccccc2)cc1>>CC(C)(C)OC(=O)COc1cccc2c1CCCC2NS(=O)(=O)c1ccc(-c2ccccc2)cc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20130345199A1,Nc1cc(Cl)ncn1.O=C(Cl)c1cccc(C(F)(F)F)n1>>O=C(Nc1cc(Cl)ncn1)c1cccc(C(F)(F)F)n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20020133015A1,CI.O=c1[nH]cc(Cl)cc1Br>>Cn1cc(Cl)cc(Br)c1=O,,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20120172448A1,CC(C)(C)OC(=O)C1(Cc2ccc(Cl)c(NCc3ccccc3)c2)CC1>>CC(C)(C)OC(=O)C1(Cc2ccc(Cl)c(N)c2)CC1,[Pd],CCOC(C)=O,,,,test
US20150166483A1,COc1c(NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)cc(C(C)(C)C)cc1NS(C)(=O)=O.COc1cc(N)cc(OCCOCCOCCN(C)C)c1>>COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)cc(NS(C)(=O)=O)c4OC)c4ccccc34)n2)cc(OCCOCCOCCN(C)C)c1,,C1CCOC1,CN(C)C=O,,,test
US20160031847A1,CC(C)(C)O.CC(C)(C)OC(=O)c1ccc(C[C@H](NC(=O)OCc2ccccc2)C(=O)O)cc1>>CC(C)(C)OC(=O)c1ccc(C[C@H](NC(=O)OCc2ccccc2)C(=O)OC(C)(C)C)cc1,CN(C)c1ccncc1,C1CCOC1,CC(C)(C)O,O,,test
US20160168095A1,O=C(Cn1ccnc1)c1ccc(C#CC2CC2)cc1Cl>>OC(Cn1ccnc1)c1ccc(C#CC2CC2)cc1Cl,,CO,,[BH4-].[Na+],,test
US20100215579A1,C=O.Nc1ccc2cc(-c3ccc(OCCOCCOCCF)cc3)ccc2c1.[BH3-]C#N>>CN(C)c1ccc2cc(-c3ccc(OCCOCCOCCF)cc3)ccc2c1,,CC(=O)O,,[Na+].[OH-],,test
US20110150833A1,C1CCOC1.CCOC(=O)C#N.O=C1CCOc2ccccc21>>CCOC(=O)C1COc2ccc(C)cc2C1=O,,C1CCOC1,CCOCC,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20070155767A1,C=CS(C)(=O)=O.Cc1nc2c(Cl)nc3ccccc3c2n1CC(C)(C)O>>Cc1nc2c(Cl)nc3ccccc3c2n1CC(C)(C)OCCS(C)(=O)=O,,C1CCOC1,,O,[H-].[Na+],test
US04877779,Br[Mg]c1ccccc1.C#CCCCO>>C#CCCC(O)c1ccccc1,,CCOCC,,Cl,[Cl-].[NH4+],test
US20150344496A1,O=P(Cl)(Cl)Cl.Oc1nc(-c2ccc(F)s2)nc2c1CSC2>>Fc1ccc(-c2nc(Cl)c3c(n2)CSC3)s1,,ClCCl,,O,,test
US20070099944A1,CC1=C(C(=O)O)C(c2ccc(F)c(F)c2)NC(=O)N1.Nc1ccc2[nH]nc(Nc3cc(F)cc(F)c3)c2c1>>CC1=C(C(=O)Nc2ccc3[nH]nc(Nc4cc(F)cc(F)c4)c3c2)C(c2ccc(F)c(F)c2)NC(=O)N1,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20070249579A1,Ic1ccccc1.c1c[nH]nn1>>c1ccc(-n2ccnn2)cc1,I[Cu]I,CN(C)C=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US04939148,C=O.CCO.CNCc1cccc2ccccc12>>CCOCN(C)Cc1cccc2ccccc12,,ClCCl,,,,test
US05869661,COc1c(F)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12.ClCc1ccccc1>>COc1c(F)c(F)cc2c(=O)c(C(=O)OCc3ccccc3)cn(C3CC3)c12,,CO,O,CN(C)C=O,[H-].[Na+],test
US20130178505A1,O=C1CCO1.Oc1cccc(Cl)c1Cl>>O=C(O)CCOc1cccc(Cl)c1Cl,,O,,Cl,[Na+].[OH-],test
US04745169,COc1ccc(CCl)cc1.Cl[Si](Cl)(Cl)Cl>>COc1ccc(C[Si](Cl)(Cl)Cl)cc1,,CCOCC,,[Mg],,test
US20130237518A1,C#C[C@@H]1CCCN(C(=O)OC(C)(C)C)C1.[N-]=[N+]=Nc1ccc2c(c1)c(-c1ccncc1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@@H](c2cn(-c3ccc4c(c3)c(-c3ccncc3)nn4C(c3ccccc3)(c3ccccc3)c3ccccc3)nn2)C1,,CC(C)(C)O,O,[Cl-].[Na+],,test
US20130331419A1,Cc1ccc(F)cc1[N+](=O)[O-].O=[N+]([O-])O>>Cc1c([N+](=O)[O-])cc(F)cc1[N+](=O)[O-],,O=S(=O)(O)O,,,,test
US05411973,C[C@](O)(C(O)Cc1ccc(S(=O)(=O)c2ccccc2)cc1)C(F)(F)F>>C[C@](O)(/C=C/c1ccc(S(=O)(=O)c2ccccc2)cc1)C(F)(F)F,,C1CCOC1,,[H-].[Na+],,test
US04129590,Cc1ccc([N+](=O)[O-])cc1C(=O)Cl.Nc1ccc(S(=O)(=O)O)c2cc(S(=O)(=O)O)cc(O)c12>>Cc1cc([N+](=O)[O-])ccc1C(=O)Nc1ccc(S(=O)(=O)O)c2cc(S(=O)(=O)O)cc(O)c12,,O,,CC(=O)[O-].[Na+],,test
US05599930,CC(C)=O.CC(C)Nc1cccnc1N1CCN(C(=O)c2cc3cc(NC(=O)N4CCNCC4)ccc3[nH]2)CC1>>CC(C)Nc1cccnc1N1CCN(C(=O)c2cc3cc(NC(=O)N4CCN(C(C)C)CC4)ccc3[nH]2)CC1,,CC(=O)O,CO,[Na+].[OH-],,test
US20040171638A1,COc1cccc(C)c1Cc1cccc2c1C(=O)NC2=O.O=C1CCC(=O)N1Br>>COc1cccc(CBr)c1Cc1cccc2c1C(=O)NC2=O,,CCOCC,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20140275047A1,BrBr.Cc1ccc(C(C)C)c(N2C(=O)CS/C2=N\C(=O)NCCc2ccc(-c3ncn(-c4ccc(OC(F)(F)F)cc4)n3)cc2)c1>>Cc1ccc(C(C)C)c(N2C(=O)C(Br)S/C2=N\C(=O)NCCc2ccc(-c3ncn(-c4ccc(OC(F)(F)F)cc4)n3)cc2)c1,,ClCCl,,,,test
US20100249108A1,COC(OC)N(C)C.O=C1Cc2ccncc2Nc2ncccc21>>CN(C)/C=C1/C(=O)c2cccnc2Nc2cnccc21,,C1CCOC1,,,,test
US20100240644A1,CC(C)(C)OC(=O)c1cc2[nH]ccc2cn1.O=C1CCC(=O)N1Cl>>CC(C)(C)OC(=O)c1cc2[nH]cc(Cl)c2cn1,,ClCCl,,,,test
US20040157836A1,COC(=O)c1c(N)ccc2c1CCCC2.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>COC(=O)c1c(NS(=O)(=O)c2ccccc2[N+](=O)[O-])ccc2c1CCCC2,,c1ccncc1,,,,test
US20150175617A1,CC1(C)CC2=NNC(=O)c3cc(F)cc4[nH]c(c2c34)C1=O>>CC1(C)CC2=NNC(=O)c3cc(F)cc4[nH]c(c2c34)C1O,,CO,,[BH4-].[Na+],,test
US20160272617A1,CC(C)N1CCC(N)CC1.Cc1cc(C(=O)O)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)c(F)c2)cc1>>Cc1cc(C(=O)NC2CCN(C(C)C)CC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)c(F)c2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150065507A1,Cc1noc(C)c1COc1ccc(S(=O)(=O)Cl)cc1.Nc1ccc(C2CC2)nn1>>Cc1noc(C)c1COc1ccc(S(=O)(=O)Nc2ccc(C3CC3)nn2)cc1,,c1ccncc1,,,,test
US20100009975A1,CN(CC=O)C(=O)OC(C)(C)C.O=[N+]([O-])c1ccc2c(c1)NCCO2>>CN(CCN1CCOc2ccc([N+](=O)[O-])cc21)C(=O)OC(C)(C)C,,CC(=O)O,ClCCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04753957,C=CCNC(C)C(=O)OC.O=C=Nc1cc(Cl)cc(Cl)c1>>C=CCN1C(=O)N(c2cc(Cl)cc(Cl)c2)C(=O)C1C,,Cc1ccccc1,,,,test
US20100324040A1,CC(C)O.Nc1cc(O)[nH]n1>>CC(C)Oc1cc(N)n[nH]1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04634710,Cc1cccnc1CCl.O=C(OO)c1cccc(Cl)c1>>Cc1ccc[n+]([O-])c1CCl,,ClCCl,,,,test
US20050288357A1,CC1CCCC1(C(=O)O)c1cccc(F)c1.CO>>COC(=O)C1(c2cccc(F)c2)CCCC1,,CO,,O=S(=O)(O)O,O=C([O-])[O-].[Na+].[Na+],test
US20130261116A1,CNC(=O)c1ccc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)cc1F.Cc1csc(B(O)O)c1>>Cc1csc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20100286211A1,N#Cc1ccc(Br)cn1.NNC(N)=S>>Nc1nnc(-c2ccc(Br)cn2)s1,,O=C(O)C(F)(F)F,,,,test
US20140088075A1,CCn1c(=O)c(-c2cc(NC(=O)Nc3cccc(F)c3)c(F)cc2Cl)cc2cnc(NCCOC)cc21.CS(=O)(=O)O>>CCn1c(=O)c(-c2cc(NC(=O)Nc3cccc(F)c3)c(F)cc2Cl)cc2cnc(NCCOC)cc21.CS(=O)(=O)O,,CC#N,,,,test
US20070004675A1,CCn1cncc1-c1cc2nccc(Oc3ccc([N+](=O)[O-])cc3F)c2s1>>CCn1cncc1-c1cc2nccc(Oc3ccc(N)cc3F)c2s1,Cl[Ni]Cl,C1CCOC1,CO,[BH4-].[Na+],,test
US20030130257A1,CCOC(=O)C(NC(C)=O)C(=O)OCC.ClCc1nccnc1CCl>>CCOC(=O)C(Cc1nccnc1CCl)(NC(C)=O)C(=O)OCC,,ClCCl,,,,test
US20120172412A1,COc1ccc(C(NCCCC[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)(c2ccccc2)c2ccccc2)cc1>>COc1ccc(C(NCCCC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20160002243A1,CC(C)(C)OC(=O)NC1CCCC(Nc2nc(Cl)nc3[nH]cnc23)C1.O=C(O)C(F)(F)F>>NC1CCCC(Nc2nc(Cl)nc3[nH]cnc23)C1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20100063117A1,CC(=O)NC[C@H]1CN(c2cc(F)c(N3CC(=NO)C4(CC4)C3)c(F)c2)C(=O)O1.CCBr>>CCON=C1CN(c2c(F)cc(N3C[C@H](CNC(C)=O)OC3=O)cc2F)CC12CC2,,CN(C)C=O,,[K+].[OH-],,test
US06201027B1,CCOC(=O)c1cc(Cl)c(S(=O)(=O)CC(=O)O)c(Cl)c1>>CCOC(=O)c1cc(Cl)c(S(C)(=O)=O)c(Cl)c1,,c1ccncc1,,Cc1ccccc1,,test
US05330998,BrC(Br)(Br)Br.Cc1oc(-c2ccccc2)nc1CCO>>Cc1oc(-c2ccccc2)nc1CCBr,,CCOCC,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070027160A1,Brc1cccc2cccnc12.O=C1CCC(=O)N1I>>Brc1cccc2cc(I)cnc12,,CC(=O)O,,,,test
US20150177262A1,CN(C)C=O.CN(C)c1ccc(/C=C/c2ccc(Br)cc2)cc1>>CN(C)c1ccc(C=Cc2ccc(C=O)cc2)cc1,,CN(C)C=O,,C1CCOC1,[Li]CCCC,test
US09273028B2,CCN(c1ncnc2c1ccn2S(=O)(=O)c1ccc(C)cc1)[C@H]1CCCN(C(=O)OCc2ccccc2)C1>>CCN(c1ncnc2c1ccn2S(=O)(=O)c1ccc(C)cc1)[C@H]1CCCNC1,[Pd],CCO,,,,test
US20070155746A1,CNC(=O)c1cc(Cl)ccn1.Nc1cccc(O)c1>>CNC(=O)c1cc(Oc2cccc(N)c2)ccn1,,CCOC(C)=O,CS(C)=O,O,CC(C)(C)[O-].[K+],test
US20050277652A1,CN1CCNCC1.Nc1cc(Oc2ccc(N)c(Cl)c2)ccn1.O=C(Cl)Oc1ccccc1>>CN1CCN(C(=O)Nc2cc(Oc3ccc(N)c(Cl)c3)ccn2)CC1,,C1CCOC1,CN(C)C=O,CCN(CC)CC,,test
US20140275015A1,CC1c2nnn(-c3cnccn3)c2C=CN1C(=O)c1ccc(F)c(Cl)c1Cl>>CC1c2nnn(-c3cnccn3)c2CCN1C(=O)c1ccc(F)c(Cl)c1Cl,,ClCCl,O=C(O)C(F)(F)F,CC[SiH](CC)CC,,test
US20080269213A1,CCOC(=O)Cc1cccc(C(NC(=O)COc2ccccc2)c2cc(Cl)c3cccnc3c2O)c1>>O=C(O)Cc1cccc(C(NC(=O)COc2ccccc2)c2cc(Cl)c3cccnc3c2O)c1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20090275753A1,CC(=O)Cl.CC1=C2OC(C)(C)CC2C(CNc2ccc(-c3ccn(C4CCCCO4)n3)cc2)C([N+](=O)[O-])=C1C>>CC(=O)N(CC1C([N+](=O)[O-])=C(C)C(C)=C2OC(C)(C)CC21)c1ccc(-c2ccn(C3CCCCO3)n2)cc1,,ClCCl,,CCN(CC)CC,,test
US05777008,CCCCN(C(C)=O)C1CC(C)(C)N(CCO)C(C)(C)C1>>CCCCNC1CC(C)(C)N(CCO)C(C)(C)C1,,Cl,,[Na+].[OH-],,test
US20080194629A1,CCNCC(C)C.COCCCCC1(CNC(=O)[C@H]2C[C@@H](C(=O)O)CN(C(=O)OC(C)(C)C)C2)c2ccccc2Oc2ccccc21>>CCN(CC(C)C)C(=O)[C@@H]1C[C@H](C(=O)NCC2(CCCCOC)c3ccccc3Oc3ccccc32)CN(C(=O)OC(C)(C)C)C1,,CCN(CC)CC,,,,test
US20160229814A1,CC(CC(=O)O)CC(=O)Nc1ccc(C#N)c(Cl)c1.CCn1c(=O)c2cc(N)ccc2n(CCC#N)c1=O>>CCn1c(=O)c2cc(NC(=O)CC(C)CC(=O)Nc3ccc(C#N)c(Cl)c3)ccc2n(CCC#N)c1=O,,CCOC(C)=O,O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20070197481A1,CC(C)(C)OC(=O)C(N)CBr.CN(C)C=O.C[C@@H](NC(=O)OCc1ccccc1)C(=O)O>>COC(=O)c1ccc(OC(C)C)c(C#N)c1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20100249385A1,CC(=O)C(C)CCCCS(=O)(=O)O.NNc1cccc(C(F)(F)F)c1>>CC1=Nc2cc(C(F)(F)F)ccc2C1(C)CCCCS(=O)(=O)O,,CC(=O)O,,,,test
US20080319033A1,CC(=O)c1ccc(-c2sc(N)nc2C)cc1.O=C(n1ccnc1)n1ccnc1>>CC(=O)c1ccc(-c2sc(NC(=O)n3ccnc3)nc2C)cc1,,C1CCOC1,ClCCl,,,test
US05424311,COC(=O)[C@@H](N)CSC.O=[N+]([O-])c1cccnc1Cl>>COC(=O)[C@H](CSC)Nc1ncccc1[N+](=O)[O-],,CCN(CC)CC,,,,test
US20090042929A1,O=C(CBr)C12CC3CC(CC(C3)C1)C2.Sc1cccs1>>O=C(CSc1cccs1)C12CC3CC(CC(C3)C1)C2,,CC#N,,CCN(CC)CC,,test
US20150218092A1,CCc1cc(N2CCC(Br)C2=O)ccc1OCCN1CCCC1.Oc1ccc(-c2ccccc2)cc1>>CCc1cc(N2CCC(Oc3ccc(-c4ccccc4)cc3)C2=O)ccc1OCCN1CCCC1,,CC#N,,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US20080293753A1,COC(=O)c1cccc(Br)n1.OB(O)c1ccc(O)cc1>>COC(=O)c1cccc(-c2ccc(O)cc2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US05075440,CC(=O)OC(C)=O.CC1=C(C(=O)OCCO)C(c2cccc(Cl)c2Cl)C2C(O)(CN(C(=O)OC(C)(C)C)CCS2(=O)=O)N1>>CC(=O)OCCOC(=O)C1=C(C)NC2=C(C1c1cccc(Cl)c1Cl)S(=O)(=O)CCNC2,,c1ccncc1,,,,test
US20060135525A1,COC(=O)[C@@H]1CC[C@@H](C(=O)[O-])CC1>>COC(=O)[C@@H]1CC[C@@H](CO)CC1,,C1CCOC1,,O,O=C([O-])O.[Na+],test
US20030109556A1,CC(=O)OC(C)=O.CNC(=O)C(Cc1ccc2ccccc2c1)N1CCN(C(=O)OC(C)(C)C)C(CCO)C1>>CNC(=O)C(Cc1ccc2ccccc2c1)N1CCN(C(=O)OC(C)(C)C)C(CCOC(C)=O)C1,,ClCCl,,c1ccncc1,,test
US05686445,Cc1ncc2c(n1)-c1ccccc1N(C(=O)c1ccc([N+](=O)[O-])cc1)CC2>>Cc1ncc2c(n1)-c1ccccc1N(C(=O)c1ccc(N)cc1)CC2,[Pd],CCO,,NN,,test
US20080113978A1,CCC(CC)c1cc(C)nn2c(-c3sc(C4=CCOCC4)nc3C)c(C)nc12>>CCC(CC)c1cc(C)nn2c(-c3sc(C4CCOCC4)nc3C)c(C)nc12,[Pd],CCO,,,,test
US20070287695A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.N[C@H]1CCCC[C@@H]1N>>CC(C)(C)OC(=O)N1CCC(N[C@H]2CCCC[C@@H]2N)CC1,,ClCCl,,O=C([O-])O.[Na+],,test
US05817674,COC(=O)c1ccccc1-c1ccc(Cc2nc(-c3ccccc3)nc3ccccc23)cc1>>O=C(O)c1ccccc1-c1ccc(Cc2nc(-c3ccccc3)nc3ccccc23)cc1,,CCO,,[Na+].[OH-],,test
US20110034436A1,N#Cc1cn2c3c(c(F)c(F)c(N)c3c1=O)OCC21CC1.NCCCc1cccnc1>>N#Cc1cn2c3c(c(NCCCc4cccnc4)c(F)c(N)c3c1=O)OCC21CC1,,CS(C)=O,,CCN(CC)CC,,test
US20130150353A1,CC(=NO)c1cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n2nccc2n1>>CC(N)c1cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n2nccc2n1,[Pd],CC(=O)O,CCO,[H][H],,test
US20140275030A1,Brc1ccc2ccccc2n1.CCCC[Sn](CCCC)(CCCC)c1ccccn1>>c1ccc(-c2ccc3ccccc3n2)nc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,,,test
US05580485,ON=C(c1ccccn1)c1ccccn1>>NC(c1ccccn1)c1ccccn1,[Zn],CCO,,N,,test
US20130102627A1,CC(=O)c1ccccc1.NC(=O)c1ccccc1>>c1ccc(-c2ccc3ccccc3n2)cc1,[Cu]I,,,,,test
US20120172584A1,O=C(Cl)c1cccnc1.Oc1ccccc1>>O=C(Oc1ccccc1)c1cccnc1,,C1CCOC1,,CCN(CC)CC,c1ccncc1,test
US20120302540A1,CC(C)(C)OC(=O)N1CCCC2(C1)C(=O)N=CN2c1ccccc1>>CC(C)(C)OC(=O)N1CCCC2(C1)C(=O)NCN2c1ccccc1,,CO,,[BH4-].[Na+],,test
US20090298815A1,Nc1cccc(-c2nc(N3CCOCC3)sc2-c2ccnc(Cl)n2)c1F.O=S(=O)(Cl)C1CCCCC1>>O=S(=O)(Nc1cccc(-c2nc(N3CCOCC3)sc2-c2ccnc(Cl)n2)c1F)C1CCCCC1,,c1ccncc1,,,,test
US20100249126A1,CN1CCC(O)CC1.O=[N+]([O-])c1ccc(Cl)nc1>>CN1CCC(Oc2ccc([N+](=O)[O-])cn2)CC1,,C1CCOC1,,[H-].[Na+],,test
US04159331,O=C=Nc1cccc(C(F)(F)F)c1.O=S(=O)(c1ccc(Nc2ccnc3cc(C(F)(F)F)ccc23)cc1)N1CCNCC1>>O=C(Nc1cccc(C(F)(F)F)c1)N1CCN(S(=O)(=O)c2ccc(Nc3ccnc4cc(C(F)(F)F)ccc34)cc2)CC1,,ClCCl,,,,test
US05807886,BrCc1ccccc1.Cl.O=[N+]([O-])c1ccc2c(c1)CNCC2>>Cl.O=[N+]([O-])c1ccc2c(c1)CN(Cc1ccccc1)CC2,,CC#N,CCOCC,CCO,O=C([O-])[O-].[K+].[K+],test
US20130225524A1,CCOC(=O)c1cccc(Nc2c(C(=O)NCc3cccc(C(=O)OC)c3)cnc3cc(-c4c(C)noc4C)ccc23)c1>>Cc1noc(C)c1-c1ccc2c(Nc3cccc(C(=O)O)c3)c(C(=O)NCc3cccc(C(=O)O)c3)cnc2c1,,CCO,,[Na+].[OH-],,test
US20140213571A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3C(CN)O4)cc12.CS(=O)(=O)Cl>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3C(CNS(C)(=O)=O)O4)cc12,,ClCCl,O,CCN(CC)CC,,test
US20150210682A1,COc1cc2c(cc1OCCCCCCNC(=O)OC(C)(C)C)CC(C(C)(C)C)n1cc(C(=O)O)c(=O)cc1-2.Cl>>COc1cc2c(cc1OCCCCCCN)CC(C(C)(C)C)n1cc(C(=O)O)c(=O)cc1-2.Cl,,CC#N,,,,test
US20080004302A1,Cc1cc(CNc2nccc(Cl)n2)on1.Nc1cc(CCc2ccncc2)n[nH]1>>Cc1cc(CNc2nccc(Nc3cc(CCc4ccncc4)n[nH]3)n2)on1,,CCO,,,,test
US20130172292A1,NN.O=C(c1ccc(OCc2ccccc2)cc1)c1ncc(F)cc1F>>Fc1cnc2c(-c3ccc(OCc4ccccc4)cc3)n[nH]c2c1,,CC(C)O,,O,O=C([O-])O.[Na+],test
US20060030609A1,CCC(C)N1C(=O)Cc2cc(NC[C@@H](O)C(=O)OC)ccc21.CCOC(C)=O>>CCC(C)N1C(=O)Cc2cc(N3C[C@H](C(=O)OC)OC3=O)ccc21,,CC#N,,,,test
US20050272791A1,CC(C)S(=O)(=O)n1c(N)nc2ccc(I)cc21.CCCC[Sn](CCCC)(CCCC)c1sc(C)nc1-c1ccccc1>>Cc1nc(-c2ccccc2)c(-c2ccc3nc(N)n(S(=O)(=O)C(C)C)c3c2)s1,,CCOC(C)=O,CN(C)C=O,,,test
US20160200695A1,Nc1ccc(NC(=O)c2ccco2)cc1.O=C(O)c1sc2ccccc2c1Cl>>O=C(Nc1ccc(NC(=O)c2sc3ccccc3c2Cl)cc1)c1ccco1,,CN(C)C=O,,O=C(Cl)C(=O)Cl,,test
US20100048881A1,CCCCCC[C@H](C)O.COCCOC(=O)N=NC(=O)OCCOC.ClCCl.O=C(O)c1ccc([N+](=O)[O-])cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CCCCCC[C@@H](C)OC(=O)c1ccc([N+](=O)[O-])cc1.CCCCCC[C@H](C)O,,ClCCl,O,,,test
US20110092505A1,CC(C)(C)OC(=O)N1CCN(c2cc(C#N)cc(-c3ccnc(NC4CCCCC4)c3)n2)CC1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1CCN(c2cc(-c3nnn[nH]3)cc(-c3ccnc(NC4CCCCC4)c3)n2)CC1,,CN(C)C=O,,[Cl-].[NH4+],,test
US20130018043A1,Cc1c(-c2ncco2)n(-c2ccccc2)c2cc(Cl)ccc2c1=O.O=C1CCC(=O)N1Br>>O=c1c(CBr)c(-c2ncco2)n(-c2ccccc2)c2cc(Cl)ccc12,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20150329552A1,CCOC(=O)c1cc2n(c1)CCCc1c(N)n[nH]c1-2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1cc2n(c1)CCCc1c(NC(=O)C(F)(F)F)n[nH]c1-2,,ClCCl,,,,test
US20030187023A1,Cc1cc(N2CCC(N(CCNC(=O)OC(C)(C)C)C(=O)CCS(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC2)ccn1>>CC(=O)NCCN(C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C1CCN(c2ccnc(C)c2)CC1,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US20110105461A1,CCCNCC.Cc1ccc(S(=O)(=O)OC[C@H]2COc3c(Cl)cc(S(C)(=O)=O)cc3O2)cc1>>CCCN(CC)C[C@H]1COc2c(Cl)cc(S(C)(=O)=O)cc2O1,,CC#N,,,,test
US20100150863A1,CCOC(=O)c1cccc(-n2nc(C(C)(C)C)cc2NC(=O)Oc2ccccc2)c1.CNC(=O)c1cc(Oc2ccc(N)c(Cl)c2)ccn1>>CCOC(=O)c1cccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(C(=O)NC)c3)cc2Cl)c1,,C1CCOC1,,CCN(CC)CC,,test
US20150005279A1,Cc1c(-c2ccc(C#N)c(N)c2N)cccc1-n1cnc2ccccc2c1=O.Cn1cc(C=O)cn1>>Cc1c(-c2ccc(C#N)c3[nH]c(-c4cnn(C)c4)nc23)cccc1-n1cnc2ccccc2c1=O,,CCOC(C)=O,CN(C)C=O,C[Si](C)(C)Cl,,test
US20140296232A1,C#CC(=O)O.Cc1cc(O)cc(C)c1Br>>C#CC(=O)Oc1cc(C)c(Br)c(C)c1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20120202287A1,CCCCCC(CC)n1cnc2c(Cl)ncnc21.N>>CCCCCC(CC)n1cnc2c(N)ncnc21,,CO,ClCCl,,,test
US20110245205A1,CC(C)(C)OC(=O)N1CCCC(=O)CC1.c1cscn1>>CC(C)(C)OC(=O)N1CCCC(O)(c2nccs2)CC1,,C1CCOC1,,[Li]CCCC,,test
US20040259859A1,COc1ccc(CN2CC3CCC(C2)C3(O)c2cccc(N)c2)cc1.CS(=O)(=O)Cl>>COc1ccc(CN2CC3CCC(C2)C3(O)c2cccc(NS(C)(=O)=O)c2)cc1,,c1ccncc1,,O,,test
US20060160877A1,Nc1ccccc1-c1cccc2cc(C(=O)N[C@H]3CN4CCC3CC4)oc12.O=C(Cl)C1CCC1>>Cl.O=C(N[C@H]1CN2CCC1CC2)c1cc2cccc(-c3ccccc3NC(=O)C3CCC3)c2o1,,C1CCOC1,CN(C)C=O,CCN(CC)CC,,test
US20090118201A1,Cc1ccc(S(=O)(=O)OCCOc2ccc(Cc3cc(Br)ccc3Cl)cc2)cc1.OC1CCCC1>>Clc1ccc(Br)cc1Cc1ccc(OCCOC2CCCC2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20040039038A1,CCCCCCC(=O)N(C)Cc1cccc(-c2ccc(C=C(CC(=O)OCC)C(=O)OC)cc2)c1>>CCCCCCC(=O)N(C)Cc1cccc(-c2ccc(CC(CC(=O)OCC)C(=O)OC)cc2)c1,[Pd],CCOC(C)=O,,,,test
US20110130433A1,CC(C)(C)OC(=O)[C@H](N)c1ccccc1.CN(C)C(=O)Cl>>CN(C)C(=O)N[C@@H](C(=O)OC(C)(C)C)c1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20150376130A1,COC(=O)c1cccnc1F.COc1cc(N)cc(Cl)c1>>COC(=O)c1cccnc1Nc1cc(Cl)cc(OC)c1,,ClCCl,,,,test
US20160145244A1,CC(C)(C)OC(=O)NCC(=O)O.Cc1cc(Nc2ncnc(Nc3ccccc3S(=O)(=O)C(C)C)n2)c2c(c1C1CCNCC1)C[C@@H](C)O2>>Cc1cc(Nc2ncnc(Nc3ccccc3S(=O)(=O)C(C)C)n2)c2c(c1C1CCN(C(=O)CNC(=O)OC(C)(C)C)CC1)C[C@@H](C)O2,,CN(C)C=O,,CCN=C=NCCCN(C)C,,test
US20130210844A1,CC(C)C(=O)NCc1cnc(C(F)F)c(C(=O)O)c1.Nc1cccc2c(NCC(F)(F)F)ncnc12>>CC(C)C(=O)NCc1cnc(C(F)F)c(C(=O)Nc2cccc3c(NCC(F)(F)F)ncnc23)c1,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20090170920A1,C[C@@H](c1ccccc1)[C@H](NC(=O)[C@@H](CC(=O)OC(C)(C)C)NC(=O)OCC1c2ccccc2-c2ccccc21)c1ncc(-c2ccc(I)cc2)[nH]1>>C[C@@H](c1ccccc1)[C@H](NC(=O)[C@H](N)CC(=O)OC(C)(C)C)c1ncc(-c2ccc(I)cc2)[nH]1,,ClCCl,,C1CCNCC1,,test
US20040167131A1,CC(C)(C)OC(=O)NC1(C(=O)Nc2ccc(-c3ccccc3S(C)(=O)=O)cc2)CC1.O=C=Nc1ccc(Cl)cc1>>CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2(NC(=O)Nc3ccc(Cl)cc3)CC2)cc1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20130131135A1,C#C[Si](C)(C)C.CCC(CC)COc1ccc(Br)cc1Cn1nc(CCC(=O)OC)cc1C>>CCC(CC)COc1ccc(C#C[Si](C)(C)C)cc1Cn1nc(CCC(=O)OC)cc1C,[Cu]I,CN(C)C=O,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070021443A1,N[C@H]1CC[C@H](O)CC1.O=[N+]([O-])c1cnc(Cl)nc1Cl>>O=[N+]([O-])c1cnc(Cl)nc1N[C@@H]1CC[C@@H](O)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20020177716A1,CCC(CC#N)NC(=O)OC(C)(C)C.CS(=O)(=O)O>>CC[C@@H](N)CC#N.CS(=O)(=O)O,,C1CCOC1,,,,test
US20140329807A1,N[C@@H]1CC[C@@H](Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1.O=C(Cl)CCl>>O=C(CCl)N[C@@H]1CC[C@@H](Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1,,CO,ClCCl,c1ccncc1,O=C([O-])O.[Na+],test
US06235680B1,Nc1ccc(S(N)(=O)=O)cc1.O=C(Cl)c1ccc(Cl)cc1Cl>>NS(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)cc2Cl)cc1,,C1COCCO1,O,c1ccncc1,,test
US20040077551A1,CC(C)(C)NC(=O)O.NS(=O)(=O)C1CC1.O=C1CCC(=O)N1Cl>>CC(C)(C)NC(=O)[O-].NS(=O)(=O)C1(Cl)CC1,,C1CCOC1,,[Li]CCCC,,test
US20010027196A1,CC#N.N#Cc1c(SCCc2ccccn2)nc(N)nc1-c1ccc(Br)o1>>N#CCc1ccc(-c2nc(N)nc(SCCc3ccccn3)c2C#N)o1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20020165241A1,Clc1nccnc1Cl.NCC1CCN(C(=O)OCc2ccc(F)cc2)CC1>>O=C(OCc1ccc(F)cc1)N1CCC(CNc2nccnc2Cl)CC1,,CCOC(C)=O,,,,test
US20100144787A1,COC(=O)COc1ccc(Cl)c2nc(OC)c(Cc3ccc(-n4cccn4)cc3)c(C)c12>>COc1nc2c(Cl)ccc(OCC(=O)O)c2c(C)c1Cc1ccc(-n2cccn2)cc1,,CO,O,CC(=O)O,[Na+].[OH-],test
US20070208018A1,COCC(C)N.CS(=O)(=O)Nn1c(=O)[nH]c2cc([N+](=O)[O-])c(F)cc2c1=O>>COCC(C)Nc1cc2c(=O)n(NS(C)(=O)=O)c(=O)[nH]c2cc1[N+](=O)[O-],,CCO,,Cl,,test
US20120202785A1,Cc1ccc(S(=O)(=O)n2c(CBr)c(-c3ccccc3)c3ccccc32)cc1.Nc1ncnc2[nH]cnc12>>Cc1ccc(S(=O)(=O)n2c(Cn3cnc4c(N)ncnc43)c(-c3ccccc3)c3ccccc32)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20100069504A1,Cl.ON=C1Cc2ccccc2CCC1NCc1ccccc1>>Cl.NC1CCc2ccccc2CC1=NO,[Pd],CCO,,,,test
US05624943,COC(=O)CCc1nc(C=O)ccc1OC>>O=Cc1ccc(O)c(CCC(=O)O)n1,,Br,,,,test
US20100210647A1,CCOC(=O)c1cc2cccc([N+](=O)[O-])c2[nH]1>>O=C(O)c1cc2cccc([N+](=O)[O-])c2[nH]1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20150018363A1,Cc1c(C2CC2C#N)nc2ccc(I)cn12.O=c1cc(OCc2ccc(Cl)cc2)cc[nH]1>>Cc1c(C2CC2C#N)nc2ccc(-n3ccc(OCc4ccc(Cl)cc4)cc3=O)cn12,[Cu]I,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=C([O-])[O-].[K+].[K+],test
US20130131039A1,COC(=O)CC(CC(=O)OC)n1cc(-c2nc(-c3cnn(C)c3)cc3nccn23)cn1>>Cn1cc(-c2cc3nccn3c(-c3cnn(C(CC(=O)O)CC(=O)O)c3)n2)cn1,,CO,O,[Li+].[OH-],,test
US20060173018A1,CC(C)(C)OC(=O)N1CC[C@H](CNC(=O)OCc2ccccc2)C1.Cc1ccc2c(Cl)nc(-c3ccccc3O)nc2c1>>Cc1ccc2c(N3CC[C@H](CNC(=O)OCc4ccccc4)C3)nc(-c3ccccc3O)nc2c1,,C1COCCO1,ClCCl,CCN(CC)CC,Cl,test
US20030130213A1,N.N=C([O-])c1nc(F)c[nH]c1=O>>N=C(N)c1nc(F)c[nH]c1=O,,CCO,,,,test
US20140296203A1,C[C@@H](NC(=O)Nc1cc2c(cn1)c(-c1ccc(F)cc1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1)c1ccccc1>>C[C@@H](NC(=O)Nc1cc2[nH]nc(-c3ccc(F)cc3)c2cn1)c1ccccc1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20020094983A1,CC1(C)CC(=O)Nc2ccc(Br)cc21.OB(O)c1cccc(F)c1>>CC1(C)CC(=O)Nc2ccc(-c3cccc(F)c3)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[K+].[K+],,test
US20120094958A1,CCOP(=O)(CNc1ccc2cc(I)cc(-c3cccc4ccccc34)c2n1)OCC.OB(O)c1cccnc1>>CCOP(=O)(CNc1ccc2cc(-c3cccnc3)cc(-c3cccc4ccccc34)c2n1)OCC,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20090176847A1,Cl.N#CC1CCCN1C(=O)CNC1CC2CC(OC(=O)Nc3ccccc3)CC2C1>>Cl.N#CC1CCCN1C(=O)CNC1CC2CC(OC(=O)Nc3ccccc3)CC2C1,,CCOCC,,,,test
US20110124637A1,CC(C)(C)OC(=O)Nc1ccc(CN2CCOCC2)nc1>>Nc1ccc(CN2CCOCC2)nc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090181965A1,Cc1cn(-c2ccc(NC(N)=S)cc2)cn1.O=C1C(Br)CCCC1c1ccccc1>>Cc1cn(-c2ccc(Nc3nc4c(s3)CCCC4c3ccccc3)cc2)cn1,,CCO,,,,test
US04028356,NNC1=Nc2ccc(Cl)cc2C(c2ccccc2F)=NC1.O=C(CBr)CBr>>Fc1ccccc1C1=NCC(NN=C(CBr)CBr)=Nc2ccc(Cl)cc21,,C1CCOC1,,,,test
US20090264474A1,Cl.Nc1cc2ncccc2s1.O=S(=O)(Cl)c1ccccc1>>Cl.O=S(=O)(Nc1cc2ncccc2s1)c1ccccc1,,c1ccncc1,,,,test
US20040097728A1,COC(=O)Cl.NNCCO>>COC(=O)N(N)CCO,,ClCCl,,CCN(CC)CC,,test
US04898607,COC(=O)c1cncn1C1c2ccccc2CCC1(C)C.O=C(OO)c1cccc(Cl)c1>>COC(=O)c1cncn1C1c2ccccc2C(=O)CC1(C)C,,ClCCl,O,O=C([O-])O.[Na+],,test
US20020115863A1,CC=CC[C@@H](C(=O)OC)[C@H](O)C(=O)OC>>CCCC[C@@H](C(=O)OC)[C@H](O)C(=O)OC,[Pd],CCOC(C)=O,,,,test
US20090209524A1,CCOC(=O)C(Cc1ccc(COC2CCCCO2)cc1)C(C)=O.N=C(N)N>>Cc1nc(N)nc(O)c1Cc1ccc(COC2CCCCO2)cc1,,CCO,,O=C(O)O,,test
US20100261771A1,CC(C)(C)OC(=O)NC(CO)c1cccc(C(F)(F)F)c1.O=C=NS(=O)(=O)Cl>>NC(=O)OCC(N)c1cccc(C(F)(F)F)c1,,CC#N,,O,O=C([O-])O.[Na+],test
US05700809,CC(C)(C)OC(=O)N1CCc2cc(OS(=O)(=O)C(F)(F)F)ccc2C1.OB(O)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)N1CCc2cc(-c3ccc(Cl)cc3)ccc2C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],,test
US06432881B1,COC(=O)c1ccc(S(C)(=O)=O)c(COc2ccnn2C)c1Cl>>Cn1nccc1OCc1c(S(C)(=O)=O)ccc(C(=O)O)c1Cl,,C1CCOC1,O,Cl,[Li+].[OH-],test
US06251827B1,COCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1Cl.O=C(O)c1ccccc1Cl>>COCCNC(=O)c1cc(S(=O)(=O)NC(=O)c2ccccc2Cl)c(Cl)cc1Cl,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US04239903,CCN(CCCCO)C1CCc2cc(OC)ccc2C1.COc1ccc(C(=O)Cl)cc1OC>>CCN(CCCCOC(=O)c1ccc(OC)c(OC)c1)C1CCc2cc(OC)ccc2C1,,c1ccccc1,,CCN(CC)CC,,test
US20060205987A1,CCCCC(CC)CO.Cl>>CCCCC(CC)CCl,,O,,,,test
US20040197358A1,CCCCC/C=C\CCCCCCCO>>CCCCC/C=C\CCCCCCC=O,,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20020025296A1,C[n+]1cccc(C(=O)O[C@@H]2[C@@H](CO)O[C@@H](n3cc(/C=C/[Si](C)(C)C)c(=O)[nH]c3=O)[C@@H]2F)c1.ClI.[I-]>>C[n+]1cccc(C(=O)O[C@@H]2[C@@H](CO)O[C@@H](n3cc(/C=C/I)c(=O)[nH]c3=O)[C@@H]2F)c1.[I-],,CC#N,,,,test
US20130109708A1,CC(C)COc1ncc(O)cc1Cl.COC(=O)c1cc(F)c(CBr)cc1F>>COC(=O)c1cc(F)c(COc2cnc(OCC(C)C)c(Cl)c2)cc1F,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070054924A1,NC[C@@H](O)CN1CCC(Oc2ccc(Cl)c(Cl)c2)CC1.O=C(O)c1cc(Br)c(=O)[nH]c1C(F)(F)F>>O=C(NC[C@@H](O)CN1CCC(Oc2ccc(Cl)c(Cl)c2)CC1)c1cc(Br)c(=O)[nH]c1C(F)(F)F,,CCN(CC)CC,,O=S(Cl)Cl,,test
US05019578,NC1CCC1.c1cc2nnnn2cc1[C@@H]1CO1>>O[C@@H](CNC1CCC1)c1ccc2nnnn2c1,,CCO,,,,test
US20150210677A1,CS(=O)(=O)Cl.NC1=C(O)C(=O)C(c2ccc(Cl)cc2)O1>>CS(=O)(=O)OC1=C(N)OC(c2ccc(Cl)cc2)C1=O,,C1CCOC1,,CCN(CC)CC,[Cl-].[NH4+],test
US05132311,N#CN=C(Oc1ccccc1)Oc1ccccc1.NC1CCN(Cc2ccccc2)CC1.c1ccc2c(c1)CCNC2>>N#CNC(=NC1CCN(Cc2ccccc2)CC1)N1CCc2ccccc2C1,,CC#N,,,,test
US20120165339A1,CCI.COc1ccc(OCc2ccccc2)cn1>>CCn1cc(OCc2ccccc2)ccc1=O,,CC#N,,,,test
US05646173,COc1ccc2c(c1)C(=O)C(CC=O)C2.C[C@H](O)CN>>COc1ccc2c(c1)-c1c(ccn1C[C@H](C)O)C2,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,O,,test
US20110009454A1,Brc1ccccc1.Oc1ccccc1F>>Fc1ccccc1Oc1ccccc1,[Cu]Br,CC(C)(C)O,,CC(C)(C)[O-].[K+],,test
US20050203153A1,COc1ccc([N+](=O)[O-])cc1-c1nc2cc(-c3ccccc3)ccc2o1>>COc1ccc(N)cc1-c1nc2cc(-c3ccccc3)ccc2o1,[Pd],,,,,test
US20080090856A1,COC(=O)Cl.Oc1ccc(F)cc1Cl>>COC(=O)Oc1ccc(F)cc1Cl,,O,,[Na+].[OH-],,test
US20070238718A1,CC(=O)Nc1nc2c(s1)C(=O)C(C(=O)C1CC1)CC2.NNc1ccccc1Cl>>CC(=O)Nc1nc2c(s1)-c1c(c(C3CC3)nn1-c1ccccc1Cl)CC2,,CC(=O)O,,Cl,O,test
US20060217372A1,CCOCCCN.COc1cc(C=O)ccc1Oc1ccc(C(N)=O)cn1.CS(=O)(=O)O>>CCOCCCNCc1ccc(Oc2ccc(C(N)=O)cn2)c(OC)c1.CS(=O)(=O)O,,CO,ClCCl,[BH4-].[Na+],,test
US20090264428A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccc(CNC(C)C)cc1>>COC(=O)c1ccc(CN(C(=O)OC(C)(C)C)C(C)C)cc1,,C1CCOC1,CCOC(C)=O,O=C([O-])O.[Na+],,test
US20110065726A1,CON(C)C(=O)c1ccc(F)cc1.COc1ccc([C@@H](C)N2CCC[C@H]2c2cncc(Br)c2)cc1>>COc1ccc([C@@H](C)N2CCC[C@H]2c2cncc(C(=O)c3ccc(F)cc3)c2)cc1,,CCOCC,,[Li]CCCC,,test
US20040162303A1,Clc1ncc(Br)c(Cl)n1.O=Cc1cc(F)cc2ccoc12>>OC(c1cnc(Cl)nc1Cl)c1cc(F)cc2ccoc12,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20120220635A1,CC(C)c1ccc(S(=O)(=O)Cc2ccc(CC(=O)O)cc2)cc1.CCCN>>CCCNC(=O)Cc1ccc(CS(=O)(=O)c2ccc(C(C)C)cc2)cc1,,c1ccncc1,,CN(C)C=O,O,test
US20150051208A1,CN1CCNCC1.NCc1ccccc1.O=[N+]([O-])c1ccc(Cl)nc1Cl>>CN1CCN(c2ccc([N+](=O)[O-])c(NCc3ccccc3)n2)CC1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US20150291582A1,C1COCCN1.Cc1cc(Cn2cc3c(Cl)nccc3n2)cnc1OCC(F)(F)F>>Cc1cc(Cn2cc3c(N4CCOCC4)nccc3n2)cnc1OCC(F)(F)F,,CC(=O)N(C)C,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US05254558,CCO.Cl.N#Cc1ccc(F)cc1>>CCOC(=N)c1ccc(F)cc1.Cl,,CCO,,C1CCOC1,,test
US05543423,NCCCn1ccnc1.O=C(Cl)c1ccc(Cl)cc1>>O=C(NCCCn1ccnc1)c1ccc(Cl)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05015659,CC(C)(C)OC(=O)C(NCC(N)=O)c1cccs1>>NC(=O)CNC(C(=O)O)c1cccs1,,CC(=O)O,,Cl,,test
US07071201B2,BrCCc1cccnc1.CC(=O)NCc1ccc2ccn(C3CCNCC3)c2c1>>CC(=O)NCc1ccc2ccn(C3CCN(CCc4cccnc4)CC3)c2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100286145A1,C=C(C)c1cnc(C)c(CN=CB=O)c1>>Cc1ncc(C(C)C)cc1CN,,CCO,,Cl,[BH4-].[Na+],test
US06127357,C=CC#N.COc1ccccc1N1CCNCC1>>COc1ccccc1N1CCN(CCC#N)CC1,,CCO,,,,test
US03980700,COC(=O)CCCCCCC1=C(C=Cc2ccccc2)C(O)CC1=O.O=C(Cl)CCl>>COC(=O)CCCCCCC1=C(C=Cc2ccccc2)C(OC(=O)CCl)CC1=O,,C1COCCO1,,c1ccncc1,,test
US20130190522A1,CC=C(c1cccc(OS(=O)(=O)c2ccc(C)cc2)c1)C(C)CN(C)C>>CCC(c1cccc(OS(=O)(=O)c2ccc(C)cc2)c1)C(C)CN(C)C,[Pd],CCO,,Cl,,test
US20130115190A1,COc1ccc2c(=O)[nH]ccc2c1.O=C1CCC(=O)N1Cl>>COc1ccc2c(=O)[nH]cc(Cl)c2c1,,CC#N,,,,test
US20090221555A1,C=CCI.C=CCc1cccc([N+](=O)[O-])c1O>>C=CCOc1c(CC=C)cccc1[N+](=O)[O-],,CCOC(C)=O,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US05045567,NCC(CC(=O)O)c1ccccc1.O>>NCC(CO)c1ccccc1,,COCCOC,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US05371101,C[Si](C)(C)N=[N+]=[N-].O=C=Nc1ccc(C(F)(F)F)cc1>>O=c1[nH]nnn1-c1ccc(C(F)(F)F)cc1,,CCOC(C)=O,,CCCCCC,,test
US20080221220A1,O=C(O)c1ccc(-c2ccc(Cl)cc2Cl)cc1.O=S(Cl)Cl>>O=C(Cl)c1ccc(-c2ccc(Cl)cc2Cl)cc1,,Cc1ccccc1,,,,test
US20100041714A1,CC(C)(C)OC(=O)COc1cccc2c1CCC[C@@H]2O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)COc1cccc2c1CCC[C@H]2N=[N+]=[N-],,Cc1ccccc1,,C1CCC2=NCCCN2CC1,,test
US20060264460A1,N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1.O=CC1CCOCC1>>N#Cc1cnc2ccc(NCC3CCOCC3)cc2c1Nc1ccc(F)c(Cl)c1,,CCO,,[BH3-]C#N.[Na+],,test
US20100056532A1,CC(C)(C)OC(=O)c1c(OS(=O)(=O)C(F)(F)F)csc1NC(=O)c1cc2ccccc2o1.Cc1ccc(B(O)O)c2cccnc12>>Cc1ccc(-c2csc(NC(=O)c3cc4ccccc4o3)c2C(=O)O)c2cccnc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20160137637A1,Nc1nc2ccccc2s1.O=C(O)c1csc(-c2ccc3c(c2)CCO3)n1>>O=C(Nc1nc2ccccc2s1)c1csc(-c2ccc3c(c2)CCO3)n1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160264554A1,CC(C)(C)OC(=O)Nc1ccc(C(=O)O)cc1.CC(C)(C)[Si](C)(C)OC1CC(N)CC(Nc2ncc(Cl)c(-c3cn(S(=O)(=O)c4ccccc4)c4ccccc34)n2)C1>>CC(C)(C)OC(=O)Nc1ccc(C(=O)NC2CC(Nc3ncc(Cl)c(-c4cn(S(=O)(=O)c5ccccc5)c5ccccc45)n3)CC(O[Si](C)(C)C(C)(C)C)C2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110118236A1,CC(NC(=O)Cn1nc(C(F)(F)F)c2c1CCN(C(=O)OC(C)(C)C)C2)c1ccc(Cl)cc1>>CC(NC(=O)Cn1nc(C(F)(F)F)c2c1CCNC2)c1ccc(Cl)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040138262A1,CC[C@@]12CC(=O)[C@](O)(c3cccnc3)C[C@H]1CCc1cc(O)ccc12.[Li]C>>CC[C@@]12C[C@@](C)(O)[C@](O)(c3cccnc3)C[C@H]1CCc1cc(O)ccc12,,C1CCOC1,,[I-].[Li+],,test
US04332948,CN(N)c1ccccc1.COc1ccccc1C=CC=O>>COc1ccccc1C=CC=NN(C)c1ccccc1,Cl,CCO,,,,test
US20080004271A1,CC(C)Cc1nc(O)c(C#N)c(-c2ccc(Cl)c(Cl)c2)n1.O=P(Cl)(Cl)Cl>>CC(C)Cc1nc(Cl)c(C#N)c(-c2ccc(Cl)c(Cl)c2)n1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20080214558A1,Clc1ccnc(Cl)n1.N#CCc1cccc(N)c1>>N#CCc1cccc(Nc2ccnc(Cl)n2)c1,,CC(C)O,,CCN(CC)CC,,test
US20160083387A1,C=C1CC[C@H]2[C@H](CCN)[C@@H]([C@@]3(C)CC[C@H](O)C[C@@H]3O)CC[C@]12C.O=C(O)c1ccc2c(c1)OCO2>>C=C1CC[C@H]2[C@H](CCNC(=O)c3ccc4c(c3)OCO4)[C@@H]([C@@]3(C)CC[C@H](O)C[C@@H]3O)CC[C@]12C,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20150252029A1,CN1CCNCC1.COC(=O)c1ccc(CBr)cc1OC>>COC(=O)c1ccc(CN2CCN(C)CC2)cc1OC,,CCO,,CCN(CC)CC,,test
US20130090386A1,CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(Br)cc1.OB(O)c1cccc(Cl)c1>>CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(-c2cccc(Cl)c2)cc1,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20060264415A1,COc1ccc(NS(=O)(=O)c2ccc(/C=C/N3C(=O)c4ccccc4C3=O)cc2)cc1OC>>COc1ccc(NS(=O)(=O)c2ccc(CCN3C(=O)c4ccccc4C3=O)cc2)cc1OC,[Pd],CCO,CCOC(C)=O,[H][H],,test
US20130230542A1,O=C(CCl)Nc1ccccc1.Oc1ccc(O)cc1>>O=C(COc1ccc(O)cc1)Nc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080039440A1,[N-]=[N+]=Nc1cc(Oc2ccc3[nH]ccc3c2)ncn1>>Nc1cc(Oc2ccc3[nH]ccc3c2)ncn1,[Pd],C1CCOC1,,,,test
US20060252812A1,FC(F)(F)c1ccc(CBr)o1.O=C1Nc2ccccc2C12COc1ccc(OS(=O)(=O)C(F)(F)F)cc12>>O=C1N(Cc2ccc(C(F)(F)F)o2)c2ccccc2C12COc1ccc(OS(=O)(=O)C(F)(F)F)cc12,,CCOC(C)=O,CN(C)C=O,[Na+].[OH-],,test
US20100298336A1,CCn1cnc(C)c1CCl.Cc1cc(O)nc(S)n1>>CCn1cnc(C)c1CSc1nc(C)cc(O)n1,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20040116478A1,CC1(C)C2CC[C@]1(CS(=O)(=O)O)C(=O)C2.CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1c1ccccc1Cl>>CC1(C)[C@@H]2CC[C@@]1(CS(=O)(=O)O)C(=O)C2.CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1c1ccccc1Cl,,CO,,,,test
US20080319031A1,COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C.O=Cc1ccc(F)cc1>>COC(=O)C(Cc1ccc(Oc2ccc(C=O)cc2)cc1)NC(=O)OC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20090298807A1,CC1(C)CNCC2(CCN(Cc3cccc(CCO)c3)CC2)O1.Cc1nc(C(=O)O)cs1>>Cc1nc(C(=O)N2CC(C)(C)OC3(CCN(Cc4cccc(CCO)c4)CC3)C2)cs1,,ClCCl,,CCN(CC)CC,CO,test
US20090197864A1,C[C@@H](Oc1c(N)ncc2c(C3=CCNCC3)coc12)c1c(Cl)ccc(F)c1Cl.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>C[C@@H](Oc1c(N)ncc2c(C3=CCN(C(=O)C(F)(F)F)CC3)coc12)c1c(Cl)ccc(F)c1Cl,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20060074071A1,CC(C)(C)OC(=O)N1CCC[C@H]1CN.O=Cc1cc2ccccc2s1>>CC(C)(C)OC(=O)N1CCC[C@H]1CNCc1cc2ccccc2s1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070275954A1,C1CNC1.O=C1Nc2ccccc2C(c2ccc(F)cc2)=NC1c1ccccc1>>Fc1ccc(C2=NC(c3ccccc3)C(N3CCC3)=Nc3ccccc32)cc1,,C1CCOC1,,,,test
US04346088,CN1C(=O)CSC1=Nc1ccccc1>>CN1C(=O)CSC1=Nc1ccccc1,,CCO,,Br,CCN(CC)CC,test
US20070112035A1,COC(=O)c1cc(OCC=C(Cl)Cl)cc(Cl)c1OC>>COc1c(Cl)cc(OCC=C(Cl)Cl)cc1C(=O)O,,CO,,[Na+].[OH-],,test
US20090197962A1,C=CCOC(=O)CCC/C=C\C[C@H]1[C@H](Cl)C[C@@H](OC2CCCCO2)[C@@H]1/C=C/[C@@H](O)CCC[C@@H](C)O>>C=CCOC(=O)CCC/C=C\C[C@H]1[C@H](Cl)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)CCC[C@@H](C)O,,CCOC(C)=O,CO,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20090156642A1,CN(Cc1cc(-c2cccnc2F)c(S(=O)(=O)c2cccc(F)c2)s1)C(=O)OC(C)(C)C.Cl>>CNCc1cc(-c2cccnc2F)c(S(=O)(=O)c2cccc(F)c2)s1.Cl,,CC(C)O,CCOC(C)=O,,,test
US20050065151A1,COc1ccc(C(=O)O)cn1.COc1cnc(N2CCOCC2)c2sc(N)nc12>>COc1ccc(C(=O)Nc2nc3c(OC)cnc(N4CCOCC4)c3s2)cn1,,C1CCOC1,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030092712A1,CCOC(=O)C#Cc1ccc(F)cc1Cl.N#CCC(N)=O>>N#Cc1c(-c2ccc(F)cc2Cl)cc(O)nc1O,,CCO,,[K+].[OH-],,test
US20160229850A1,CC#N.COC(=O)c1ccncc1.NNc1ccccc1>>Nc1cc(-c2ccncc2)nn1-c1ccccc1,,C1CCOC1,CCO,CC(C)(C)[O-].[K+],,test
US20130252934A1,CC(C)(C)[Si](C)(C)OCC[C@H](OS(C)(=O)=O)c1ccc(Cl)c(F)c1.O=c1cc(-c2ccnc(NC3CCOCC3)n2)cc[nH]1>>CC(C)(C)[Si](C)(C)OCC[C@H](c1ccc(Cl)c(F)c1)n1ccc(-c2ccnc(NC3CCOCC3)n2)cc1=O,,CC1CCCO1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20060276481A1,C1CNCCN1.CN(C)C=O.Fc1ccc2nc(Cl)ccc2c1>>O=CN1CCN(c2ccc3cc(F)ccc3n2)CC1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20150065482A1,Nc1n[nH]c2nnc(Cl)cc12>>Nc1n[nH]c2nnccc12,[Pd],CO,,[Na+].[OH-],,test
US20060069140A1,COC(=O)c1ccc(C(=O)NN=C(C)c2c(C)nn(-c3ccc(C(F)(F)F)cn3)c2O)cc1>>CC1=NN(c2ccc(C(F)(F)F)cn2)C(=O)C1=C(C)NNC(=O)c1ccc(C(=O)O)cc1,,CO,,Cl,[Na+].[OH-],test
US20100305096A1,CC1(O)CN(C2CN(C(=O)OC(C)(C)C)C2)C1>>CC1(O)CN(C2CNC2)C1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20080300242A1,CCc1cc(N)c(OC)cc1N1CCC(N2CCN(S(C)(=O)=O)CC2)CC1.COc1ccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)cc1C(=O)Nc1c(F)cccc1F>>CCc1cc(Nc2nccc(-c3c(-c4ccc(OC)c(C(=O)Nc5c(F)cccc5F)c4)nc4ccccn34)n2)c(OC)cc1N1CCC(N2CCN(S(C)(=O)=O)CC2)CC1,,OCC(F)(F)F,,Cl,,test
US20030069297A1,CCN(CC)CCNC(=O)c1c(C)[nH]c(C=O)c1C.O=C1Cc2c(cccc2-c2cccc(Cl)c2)N1>>CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3cccc(-c4cccc(Cl)c4)c32)c1C,C1CCNCC1,CCO,,,,test
US20150266857A1,C=Cc1nc2ccc(-c3cn(S(=O)(=O)c4ccccc4)c4cc(F)ccc34)cc2o1.O=C(O)C1CNCCN1>>O=C(O)C1CN(CCc2nc3ccc(-c4c[nH]c5cc(F)ccc45)cc3o2)CCN1,,CO,,[Na+].[OH-],,test
US06809097B1,COCCOc1cc2nccc(Cl)c2cc1C#N.Cc1cc(F)c(N)cc1O.Cl>>COCCOc1cc2nccc(Nc3cc(O)c(C)cc3F)c2cc1C#N.Cl,,CC(C)O,,,,test
US20040019098A1,CC(=O)Cl.Nc1ccc2c(c1)C(=C1C(=O)Nc3ccc(Cl)cc31)OC2>>NC(=O)Cc1ccc2c(c1)C(=C1C(=O)Nc3ccc(Cl)cc31)OC2,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20140371212A1,O=C(O)c1cnc(Cl)cn1.OCC1CCO1>>O=C(O)c1cnc(OCC2CCO2)cn1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20100093727A1,CS(=O)(=O)OCCCN1CC(O)C2(CC2)C1.Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(O)ccc34)cn2)c(=O)n(-c2ccccc2)n1C>>Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(OCCCN5CC(O)C6(CC6)C5)ccc34)cn2)c(=O)n(-c2ccccc2)n1C,,CC(=O)N(C)C,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05444082,O=C(O)Cc1cccs1.OC1CCC2(CC1)CCC(CCc1ccoc1)CC2>>CC(=O)SC1CCC2(CCC(CCc3ccoc3)CC2)CC1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04721809,CC(C)NCCN.CS(=O)(=O)Nc1ccc(S(=O)(=O)Cl)cc1>>CC(C)NCCNS(=O)(=O)c1ccc(NS(C)(=O)=O)cc1,,ClCCl,,CCN(CC)CC,,test
US03957526,C=C(C)C(=O)Cl.C=C(C)C(=O)OC.CC(C)(C#N)N=NC(C)(C)C#N.CCCCC/C=C\C/C=C\CCCCCCCC(=O)OC.CCCCC/C=C\C/C=C\CCCCCCCCO>>C=C(C)C(=O)O.C=C(C)C(=O)OC.C=C(C)C(=O)OCCCCCCCC/C=C\C/C=C\CCCCC,,c1ccccc1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090170828A1,CC(C)(C)OC(=O)N1CC(=O)C1.FC(F)(F)c1ccccc1CP(Br)(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1CC(=Cc2ccccc2C(F)(F)F)C1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20150119380A1,CC(=O)OC(C)=O.O=Cc1ccc(F)cc1O>>O=c1ccc2ccc(F)cc2o1,,[NH4+],[OH-],CCN(CC)CC,,test
US05124330,C1CNCCN1.Cc1cccc(CBr)c1>>Cc1cccc(CN2CCNCC2)c1,,CCOCC,c1ccccc1,,,test
US20080021059A1,CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(CO)n2n1>>CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(C=O)n2n1,O=[Mn]=O,C1CCOC1,,,,test
US04340600,C=O.COc1ccccc1CNCC(O)c1ccc(OC)c(OC)c1>>COc1ccccc1CN(C)CC(O)c1ccc(OC)c(OC)c1,,O=CO,,,,test
US20040209948A1,CCI.O=C1CCN(Cc2ccccc2)CC1>>CCC1CN(Cc2ccccc2)CCC1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04990515,CN1CCNCC1.O=C(O)c1cn(CCF)c2nc3cc(Cl)c(F)cc3cc2c1=O>>CN1CCN(c2cc3nc4c(cc3cc2F)c(=O)c(C(=O)O)cn4CCF)CC1,,c1ccncc1,,,,test
US20160068489A1,Cc1nc(NC(=O)C2CCCC2)c(C)c(C)c1OCc1ccccc1>>Cc1nc(NC(=O)C2CCCC2)c(C)c(C)c1O,[Pd],,,CO,,test
US20070225308A1,COc1c(Br)cc(-c2cccc(Cl)c2)c2cnc(N)nc12.ICI>>COc1c(Br)cc(-c2cccc(Cl)c2)c2cnc(I)nc12,[Cu]I,C1CCOC1,,CC(C)CCON=O,,test
US20090312317A1,Cc1cc(=O)oc2cc(O)ccc12.O=C(Cl)c1ccccc1>>Cc1cc(=O)oc2cc(OC(=O)c3ccccc3)ccc12,,C1CCOC1,,CCN(CC)CC,,test
US20130059847A1,O=[N+]([O-])c1cccc(-c2nc(Cl)ncc2Nc2cccc(F)c2)c1>>Nc1cccc(-c2nc(Cl)ncc2Nc2cccc(F)c2)c1,[Pd],CCO,,[H][H],,test
US04196208,CC(C)(C)OC(=O)N=[N+]=[N-].CCCCCCCCCCCCCCCCNc1ccc(C(=O)O)cc1.O=C(n1ccnc1)n1ccnc1>>CCCCCCCCCCCCCCCCN(C(=O)OC(C)(C)C)c1ccc(C(=O)c2ncc[nH]2)cc1,,c1ccncc1,,C1COCCO1,,test
US04507316,CC(CBr)C(=O)N(CC(=O)OC(C)(C)C)C1CCCC1.N#CSC#N>>CC(CSC#N)C(=O)N(CC(=O)OC(C)(C)C)C1CCCC1,,CCO,O,[K],,test
US20010047100A1,CC1(CO)CC1c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>CC1(C=O)CC1c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1,,ClCCl,,CS(C)=O,O=C(Cl)C(=O)Cl,test
US20090270359A1,CCOC(=O)c1ccc(C(C)Br)cc1.Cc1n[nH]c(C)c1-c1ccc(C#N)c(Cl)c1>>Cc1nn(C(C)c2ccc(C(=O)O)cc2)c(C)c1-c1ccc(C#N)c(Cl)c1,,CN(C)C=O,,[Na+].[OH-],,test
US20020052349A1,CSCCN(C(=O)c1ccc(F)cc1)c1ccc(S(=O)(=O)NC(C)=O)cc1>>CCNS(=O)(=O)c1ccc(N(CCSC)Cc2ccc(F)cc2)cc1,,C1CCOC1,,B,,test
US20130274241A1,O=C1CCCCC1.O=[N+]([O-])c1ccc(C2=CC3CCC(C2)N3)cc1>>O=[N+]([O-])c1ccc(C2=CC3CCC(C2)N3C2CCCCC2)cc1,,ClCCCl,,O=C([O-])O.[Na+],,test
US05439917,Cc1[nH]c2ncccc2c1SC#N.O=C(CCl)c1ccccc1>>Cc1nc2n(CC(=O)c3ccccc3)cccc-2c1SC#N.Cl,,CC#N,CN(C)C=O,,,test
US20030114422A1,CC(=O)Nc1cccc2c1CN(C)C2.Cl>>CC(=O)Nc1ccc(Cl)c2c1CN(C)C2,,CCO,,[Na+].[O-]Cl,,test
US20020019396A1,CC(Br)C(=O)c1cccc(Cl)c1.CC(C)(N)CO>>C[C@H]1NC(C)(C)CO[C@]1(O)c1cccc(Cl)c1,,CO,,,,test
US20120184542A1,Cc1ncc2cc(C(=O)Nc3cc(C(=O)NC(CNC(=O)OC(C)(C)C)c4ccccc4)ccc3Cl)c(=O)[nH]c2n1.Cl>>Cc1ncc2cc(C(=O)Nc3cc(C(=O)NC(CN)c4ccccc4)ccc3Cl)c(=O)[nH]c2n1.Cl,,C1COCCO1,,,,test
US20050234057A1,CC(C)(C)OC(=O)N1CCC(NC(=O)C2(NC(=O)c3cc4ccccc4o3)CCCCC2)C(O)C1.Cl>>Cl.O=C(NC1(C(=O)NC2CCNCC2O)CCCCC1)c1cc2ccccc2o1,,CCOCC,,CCOC(C)=O,,test
US20110183983A1,O=[N+]([O-])c1ccc(Oc2ccnn3ccc(Br)c23)c(F)c1>>Nc1ccc(Oc2ccnn3ccc(Br)c23)c(F)c1,[Zn],C1CCOC1,,CO,[Cl-].[NH4+],test
US20100256365A1,O=Cc1cccc([N+](=O)[O-])c1.c1cncc(-c2cnc3[nH]ccc3c2)c1>>O=[N+]([O-])c1cccc(C(O)c2c[nH]c3ncc(-c4cccnc4)cc23)c1,,CO,,O,[K+].[OH-],test
US04702763,CC(C)=O.OCC(S)CS>>CC1(C)SCC(CO)S1,Cl,C1CCCCC1,,,,test
US20100210623A1,Cn1cc(-c2cnc3[nH]cc(-c4cncc(N5CCN(C(=O)OC(C)(C)C)CC5)n4)c3c2)cn1>>Cn1cc(-c2cnc3[nH]cc(-c4cncc(N5CCNCC5)n4)c3c2)cn1,,C1COCCO1,,Cl,,test
US20040077854A1,O=C(NCc1cccs1)c1ccc(Cl)cc1.O=S(=O)(O)Cl>>O=C(NCc1ccc(S(=O)(=O)Cl)s1)c1ccc(Cl)cc1,,ClCCl,,,,test
US20090182023A1,CC(=O)NCCC1CCc2ccc(N)c(O)c21.CCOC(=S)[S-]>>CC(=O)NCCC1CCc2ccc3nc(S)oc3c21,,CCOC(C)=O,c1ccncc1,Cl,,test
US05010088,CC(=O)OC(C)=O.O=c1ccc2cc(N3CCC(O)CC3)ccc2[nH]1>>CC(=O)OC1CCN(c2ccc3[nH]c(=O)ccc3c2)CC1,,O,,c1ccncc1,O=C([O-])O.[Na+],test
US20140275154A1,CC(N[S@](=O)C(C)(C)C)(c1ncon1)C1CC1.Cl>>CC(N)(c1ncon1)C1CC1.Cl,,CO,,,,test
US05728801,Clc1ccc(I)cc1.Clc1ccccc1Cl.c1ccc(Nc2ccc(Nc3ccccc3)cc2)cc1>>Clc1ccc(N(c2ccccc2)c2ccc(N(c3ccccc3)c3ccc(Cl)cc3)cc2)cc1,[Cu],CCCCCC,ClCCl,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US20090076070A1,CC(O)C(F)(F)F.N#Cc1ccc(F)c(Cl)c1>>CC(Oc1ccc(C#N)cc1Cl)C(F)(F)F,,C1CCOC1,CCOC(C)=O,[H-].[Na+],[Cl-].[NH4+],test
US20160122339A1,CCOP(=O)(OCC)OC(F)(F)Br.Cn1nccc1-c1cnc2ccc(Br)cc2c1O>>Cn1nccc1-c1cnc2ccc(Br)cc2c1OC(F)F,,CC#N,,[K+].[OH-],,test
US20080269210A1,CC(C)(N)c1cc2nc(Cl)nc(N3CCOCC3)c2s1.CC1(C)OB(c2cnc(N)nc2)OC1(C)C.O=C(Cl)c1ccccc1>>CC(C)(NC(=O)c1ccccc1)c1cc2nc(-c3cnc(N)nc3)nc(N3CCOCC3)c2s1,,Cl,ClCCl,CCN(CC)CC,,test
US20080176862A1,COc1cc(OS(C)(=O)=O)cc(B2OC(C)(C)C(C)(C)O2)c1.COc1ccc(C2(c3cccc(Br)c3)N=C(N)N(C)C2=O)cc1>>COc1ccc(C2(c3cccc(-c4cc(OC)cc(OS(C)(=O)=O)c4)c3)N=C(N)N(C)C2=O)cc1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20040077669A1,CC#CCOc1cc(C(=O)c2ccccc2)ncn1.CCON>>CC#CCOc1cc(C(=NOCC)c2ccccc2)ncn1,,c1ccncc1,,Cl,Cl,test
US20080167307A1,CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCOc2ccc(C(=O)O)cc2)cs1.Nc1ccccc1>>CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCOc2ccc(C(=O)Nc3ccccc3)cc2)cs1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20060211730A1,CC1=CCCCC1.O=C=NS(=O)(=O)Cl>>CC12CCCCC1C(=O)N2,,ClCCl,,,,test
US20070185171A1,CC(=O)OC(C)=O.N#Cc1ccnc2[nH]ccc12>>CC(=O)NCc1ccnc2c1ccn2C(C)=O,[Pd],CCN(CC)CC,,CCOC(C)=O,,test
US05935945,CCOC(=O)CC#N.COc1ccc(NN=C(Sc2ccc(C)cc2)C(C)=O)cc1>>COc1ccc(-n2nc(Sc3ccc(C)cc3)c(C)c(C#N)c2=O)cc1,,ClCCl,,C,O=C[O-].[NH4+],test
US20090082358A1,FC(F)(F)c1ccc(C2NCCc3cccnc32)cc1.O=C=Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)N1CCc2cccnc2C1c1ccc(C(F)(F)F)cc1,,ClCCCl,,,,test
US05162354,BrBr.O=C1NCC(CCl)O1>>O=C1OC(CCl)CN1Br,,[Na+],[OH-],,,test
US20140296136A1,CC(C)(C)OC(=O)NS(=O)(=O)C1CC1.COCCOCCl>>COCCOCC1(S(=O)(=O)NC(=O)OC(C)(C)C)CC1,,C1CCOC1,,[Li]CCCC,,test
US20160237090A1,C[C@H]1Cn2ncc(N3CN(S(C)(=O)=O)CC3=O)c2CN1C(=O)OC(C)(C)C.O=C(Nc1cc(F)c(F)c(F)c1)Oc1ccccc1>>C[C@H]1Cn2ncc(N3CN(S(C)(=O)=O)CC3=O)c2CN1C(=O)Nc1cc(F)c(F)c(F)c1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,Cl,test
US20120088799A1,CC(C)(C)OC(=O)N1CC[C@@H](C2CO2)C1>>CC(C)(C)OC(=O)N1CC[C@@H]([C@H]2CO2)C1,,O,,,,test
US20110053916A1,CC(=O)OC(C)=O.CC(C)(C)NS(=O)(=O)c1ccc(-c2ncc(Br)c(Nc3cc(C4CC4)[nH]n3)n2)s1>>CC(=O)n1nc(Nc2nc(-c3ccc(S(=O)(=O)NC(C)(C)C)s3)ncc2Br)cc1C1CC1,,C1CCOC1,O,,,test
US20100099712A1,C/C=C/c1ccccc1.CCOC(=O)C(Cl)=NNc1ccc(Cl)cc1Cl>>CCOC(=O)C1=NN(c2ccc(Cl)cc2Cl)[C@@H](C)[C@@H]1c1ccccc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20020147214A1,Brc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1.C1COCCO1.CCCC[Sn](CCCC)(CCCC)c1cnnn1C>>CCCC(C)C.CCOC(C)=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,,,test
US20110224204A1,c1ccc(-c2ccc(OCc3ccc4ccccc4n3)cc2)c(OC2CCCCO2)c1>>Oc1ccccc1-c1ccc(OCc2ccc3ccccc3n2)cc1,,CO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20090082434A1,Cc1ccc(S(=O)(=O)OCC2Cc3cccc(Br)c3O2)cc1.OB(O)c1cccc(F)c1>>Cc1ccc(S(=O)(=O)OCC2Cc3cccc(-c4cccc(F)c4)c3O2)cc1,Cc1ccccc1[P](c1ccccc1C)(c1ccccc1C)[Pd](Cl)(Cl)[P](c1ccccc1C)(c1ccccc1C)c1ccccc1C,,,O=C([O-])[O-].[K+].[K+],,test
US20080125436A1,COc1cc(-c2nnc(S(C)(=O)=O)n2C)ccn1>>Cn1c(-c2cc[nH]c(=O)c2)nnc1S(C)(=O)=O,,CC(=O)O,CCO,Br,,test
US20160096839A1,COCCn1ncc2cc(Cl)cc(B3OC(C)(C)C(C)(C)O3)c21.COc1cc(Cl)ncn1>>COCCn1ncc2cc(Cl)cc(-c3cc(OC)ncn3)c21,,CCO,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20130172384A1,O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(Br)cc3)n[nH]c2=O)C1.OB(O)c1ccc(Cl)cc1>>O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(-c4ccc(Cl)cc4)cc3)n[nH]c2=O)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US05891889,CC(C)(C)OC(=O)N1CCC(CO)(Cc2cccc(OC(F)(F)F)c2)CC1.Cl>>Cl.OCC1(Cc2cccc(OC(F)(F)F)c2)CCNCC1,,ClCCl,,,,test
US20070032515A1,COCCOc1ccc(CO)cc1OCCOC.O=S(Cl)Cl>>COCCOc1ccc(CCl)cc1OCCOC,,C1CCOC1,,O,c1ccncc1,test
US20120208806A1,CC(C)NCCCn1c(Sc2cc3c(cc2I)OCO3)nc2c(N)ncnc21.O=Cc1ccc(B(O)O)cc1>>CC(C)NCCCn1c(Sc2cc3c(cc2-c2ccc(C=O)cc2)OCO3)nc2c(N)ncnc21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,CN(C)C=O,O=C([O-])O.[Na+],test
US20160229814A1,Nc1ccc([N+](=O)[O-])cc1C(=O)NCC1CC1.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2ccc([N+](=O)[O-])cc2c(=O)n1CC1CC1,,C1CCOC1,,O,,test
US20160185785A1,CC(C)(C)OC(=O)N1CCC2(CC1)OC2CO[Si](C)(C)C(C)(C)C.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1CCC(O)(C(CO[Si](C)(C)C(C)(C)C)N=[N+]=[N-])CC1,,CCOC(C)=O,CN(C)C=O,[Cl-].[NH4+],,test
US20140343068A1,CC(C)(C)OC(=O)Oc1ccc(F)c(C(=O)c2ccc3ncc(Cl)nc3c2)c1F>>O=C(c1ccc2ncc(Cl)nc2c1)c1c(F)ccc(O)c1F,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100221749A1,NOCC(=O)O.O=C(Cl)OCC1c2ccccc2-c2ccccc21>>O=C(O)CONC(=O)OCC1c2ccccc2-c2ccccc21,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20110319385A1,Cc1cc2c(cc1C(=O)O)[nH]c(=O)c1nnc(C3CCC(F)(F)CC3)n12.Fc1ccc2c(c1)CCN2>>Cc1cc2c(cc1C(=O)N1CCc3cc(F)ccc31)[nH]c(=O)c1nnc(C3CCC(F)(F)CC3)n12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US05244888,COC1c2ccccc2C2CN(CCN)CC21.ClCCl.O=C(Cl)c1ccc(F)cc1>>COC1c2ccccc2C2CN(CCNC(=O)c3ccc(F)cc3)CC21.Cl,,CCN(CC)CC,ClCCl,,,test
US20080287479A1,COC(=O)c1cc2[nH]c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c2cc1F>>CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3cc(C(=O)O)c(F)cc32)CC1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20040157909A1,CC(=O)NC1CCN(CCN)C1.Cc1cc(C(=O)O)c(/C=C2\C(=O)Nc3cccc(-c4cccc(F)c4)c32)[nH]1>>CC(=O)NC1CCN(CCNC(=O)c2cc(C)[nH]c2/C=C2\C(=O)Nc3cccc(-c4cccc(F)c4)c32)C1,,C1CCOC1,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
US05200422,COc1ccc(Cl)cc1-n1c(=O)[nH]c2ccccc21>>O=c1[nH]c2ccccc2n1-c1cc(Cl)ccc1O,,Br,CC(=O)O,O,,test
US20090286833A1,CCOC(=O)CP(=O)(OCC)OCC.CN(C)C(c1cccc(F)c1)C1CCC(C=O)CC1>>CCOC(=O)C=CC1CCC(C(c2cccc(F)c2)N(C)C)CC1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US05424329,COC(=O)c1c(SC)c2cc(OC)ccc2n1C>>COc1ccc2c(c1)c(SC)c(C(=O)O)n2C,,CO,O,[K+].[OH-],,test
US20070232645A1,COC(=O)c1cccc(O)c1.O=[N+]([O-])c1cc(Cl)ccc1Br>>COC(=O)c1cccc(Oc2ccc(Cl)cc2[N+](=O)[O-])c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04472305,CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C)C(N)=O>>CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCCN1)C(N)=O,,CC(=O)O,,Cl,,test
US20100168094A1,O=[N+]([O-])c1cc(OCc2ccccc2)c(C2CCCC2)cc1C(F)(F)F>>Nc1cc(OCc2ccccc2)c(C2CCCC2)cc1C(F)(F)F,[Fe],CCO,,Cl,,test
US20080293689A1,CCOC(=O)CBr.c1c[nH]c(Sc2cccs2)c1>>CCOC(=O)Cn1cccc1Sc1cccs1,C1COCCOCCOCCOCCOCCO1,C1CCOC1,,O,CC(C)(C)[O-].[K+],test
US20080306082A1,CN1CCN(CCCN)CC1.Cc1cnc(Cl)nc1-c1cc2ccc(NC(=O)OC(C)(C)C)cc2s1>>Cc1cnc(NCCCN2CCN(C)CC2)nc1-c1cc2ccc(NC(=O)OC(C)(C)C)cc2s1,,C1COCCO1,,,,test
US20020187978A1,Brc1ccncc1.CC1(C)OB(c2cccc3[nH]ccc23)OC1(C)C>>c1cc(-c2ccncc2)c2cc[nH]c2c1,[Pd],C1CCOC1,,Cl,[Na+].[OH-],test
US07071175B1,BrC(Br)(Br)Br.C=Cc1cc(CO)cnc1NC(=O)OC(C)(C)C.ClCCl>>CC(C)(C)OC(=O)Nc1ncc(CBr)cc1Cl,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04616086,CC(C)(C)c1cc(CCC(=O)O)cc(C(C)(C)C)c1O.CCOC(=O)c1ccc(N2CCNCC2)cc1>>CCOC(=O)c1ccc(N2CCN(C(=O)CCc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)CC2)cc1,,Cc1ccccc1C,,,,test
US20150045367A1,O=Cc1ccccc1F.Oc1ccc(Cl)cc1>>O=Cc1ccccc1Oc1ccc(Cl)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US08877747B2,COc1ccc(C(=O)/C=C/c2ccccc2)c(Br)c1>>COc1ccc2c(c1)C(c1ccccc1)=CC2=O,Cl[Pd]Cl,CCOC(C)=O,CN(C)C=O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,O=C([O-])[O-].[K+].[K+],test
US20160009677A1,COC(=O)c1cccc(B2OC(C)(C)C(C)(C)O2)c1C.O=C1CCC(=O)N1Br>>COC(=O)c1cccc(B2OC(C)(C)C(C)(C)O2)c1CBr,,CC#N,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20050245503A1,CN1CC[C@@H](NS(=O)(=O)c2cnc(NN)c(Cl)c2)C1=O.Fc1cccc2c1CCc1ccncc1C2N=C=S>>CN1CC[C@@H](NS(=O)(=O)c2cnc(NNC(=S)NC3c4cnccc4CCc4c(F)cccc43)c(Cl)c2)C1=O,,CC(=O)N(C)C,,,,test
US20060173008A1,CCn1nc(-c2ccccc2)c(C(C)=O)c([N+](=O)[O-])c1=O.Nc1c(Cl)cncc1Cl>>CCn1nc(-c2ccccc2)c(C(C)=O)c(Nc2c(Cl)cncc2Cl)c1=O,,C1CCOC1,CCOC(C)=O,Cl,[H-].[Na+],test
US20100113774A1,COC(=O)CN1Cc2ccccc2N(CC(=O)Nc2cc(Cl)c(OC)cc2OC)C1=O>>COc1cc(OC)c(NC(=O)CN2C(=O)N(CC(=O)O)Cc3ccccc32)cc1Cl,,CO,,Cl,[K+].[OH-],test
US06537948B1,CCOC(=O)CO.O=[N+]([O-])c1cccnc1Cl>>CCOC(=O)COc1ncccc1[N+](=O)[O-],,CN(C)C=O,,C1CCOC1,[H-].[Na+],test
US20090036492A1,Fc1ccc(CBr)c(F)c1.O=Cc1ccc(O)c2ccccc12>>O=Cc1ccc(OCc2ccc(F)cc2F)c2ccccc12,,CN(C)C=O,,Cl,[H-].[Na+],test
US20050038072A1,O=C1CCNCC1C(c1ccc(F)cc1)c1ccc(F)cc1.OCc1ccc(O)cc1>>O=C1CCN(Cc2ccc(O)cc2)CC1C(c1ccc(F)cc1)c1ccc(F)cc1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20080234255A1,CN1C(=O)CCN(C2CCCC2(C)C)c2nc(Cl)ncc21.COc1cc(C(=O)O)ccc1N>>COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1(C)C)CCC(=O)N2C,Cl,O,,CCO,,test
US20150175602A1,CC(C)(C)OC(=O)N1CCC(Sc2ccc(F)cc2F)CC1.O=S([O-])OO>>CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc(F)cc2F)CC1,,C1CCOC1,CO,O,,test
US20090163471A1,CNc1cccc(C(=O)OC)c1C>>CNc1cccc(C(=O)O)c1C,,CO,,[Li+].[OH-],,test
US20040014759A1,COc1ccc(-c2nc3cccnc3[nH]2)cc1N.O=S(=O)(Cl)c1cccs1>>COc1ccc(-c2nc3cccnc3[nH]2)cc1NS(=O)(=O)c1cccs1,,c1ccncc1,,O,,test
US06265411B1,COc1cc2c(=O)n(COC(=O)C(C)(C)C)cnc2cc1OCCN1CCCC1>>COc1cc2c(=O)[nH]cnc2cc1OCCN1CCCC1,,CO,,N,,test
US04985419,CC(CN1CCCC1)N1c2ccccc2Sc2ccc(C(=O)Cl)cc21.COc1ccccc1CN>>COc1ccccc1CNC(=O)c1ccc2c(c1)N(C(C)CN1CCCC1)c1ccccc1S2,,ClCCl,,Cl,,test
US20110015187A1,C=O.COc1ncccc1C(=O)NC1CNCCn2c1nc(-c1ccncn1)cc2=O>>COc1ncccc1C(=O)NC1CN(C)CCn2c1nc(-c1ccncn1)cc2=O,,CC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20110263428A1,CC(C)(C)C(=O)Cl.Cc1cc(C)c(C2C(=O)CC(CC3CCOCC3)C2=O)c(C)c1>>Cc1cc(C)c(C2=C(OC(=O)C(C)(C)C)CC(CC3CCOCC3)C2=O)c(C)c1,,ClCCl,,CCN(CC)CC,,test
US20030216373A1,CC(=O)OCC(=O)N1CC=C(c2ccc(N3C[C@H](Cn4ncnn4)OC3=O)cc2F)CC1>>O=C(CO)N1CC=C(c2ccc(N3C[C@H](Cn4ncnn4)OC3=O)cc2F)CC1,,CO,,N,,test
US20120196864A1,CNC1=NC(=O)SC1.COc1ccc(C=O)cc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F>>CNC1=NC(=O)S/C1=C\c1ccc(OC)c(OCc2ccc(C(F)(F)F)cc2C(F)(F)F)c1,,CCO,CCOC(C)=O,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US20090227600A1,CC(C)(C)OC(=O)C(N)Cc1cscn1.O=Cc1nccs1>>CC(C)(C)OC(=O)C(Cc1cscn1)N=Cc1nccs1,,ClCCl,,O=S(=O)([O-])[O-].[Mg+2],,test
US20160176869A1,CN(C)C=O.NC(=O)c1cc(F)c(Cl)nc1Cl>>O=C1NC(O)c2c(F)c(Cl)nc(Cl)c21,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04321372,CCC(=O)C(C)Br.NC(N)=S>>CCc1nc(N)sc1C,,CCO,,,,test
US20140243310A1,C[Mg]Br.O=C(COC1CCc2nc(-c3ccc(OCC4CC4)c(F)c3)oc2C1)N1CCOCC1>>CC(O)COC1CCc2nc(-c3ccc(OCC4CC4)c(F)c3)oc2C1,,C1CCOC1,,[Cl-].[NH4+],,test
US20150210734A1,C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=O.O=C(CBr)OCc1ccccc1>>C[C@]12CC[C@@H]3c4ccc(OCC(=O)OCc5ccccc5)cc4CC[C@H]3[C@@H]1CCC2=O,,O,,C1CCOC1,O=C([O-])[O-].[K+].[K+],test
US20140113894A1,C[C@@](CO)(NC(=O)CCl)c1cc(Br)cc([N+](=O)[O-])c1>>C[C@H]1OCC(=O)NC1c1cc(Br)cc([N+](=O)[O-])c1,,CC(C)(C)O,,O,CC(C)(C)[O-].[K+],test
US20140315909A1,C=CC(=O)Nc1cccc(-c2cnc3[nH]nc(C)c3c2)c1.C=CC(=O)Nc1cccc(B(O)O)c1>>C=CC(=O)Nc1cccc(-c2cnc3[nH]cc(C)c3c2)c1,,CCO,ClCCl,O=C([O-])[O-].[Na+].[Na+],,test
US20130109661A1,CCOC(CCl)OCC.Nc1nnc(Cl)cc1Br>>Clc1cc(Br)c2nccn2n1,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05206375,CN(C)C=Nc1scc(Cl)c1C#N.O=CO>>N#Cc1c(Cl)csc1NC=O,,O,,,,test
US05910498,CCO.CCOC(=O)c1cn(-c2cc([N+](=O)[O-])c(F)cc2F)c2nc(Cl)c(F)cc2c1=O.ClCCl.c1ccncc1>>CC(C)OC(C)C.CCOC(=O)c1cn(-c2cc(N)c(F)cc2F)c2nc(Cl)c(F)cc2c1=O,[Pd],c1ccncc1,,Cl,,test
US20130085123A1,BrCc1ccc(-n2cccn2)cc1.COc1ccc(Cn2c(=O)n(C)c(=O)c3c[nH]nc32)cc1>>COc1ccc(Cn2c(=O)n(C)c(=O)c3cn(Cc4ccc(-n5cccn5)cc4)nc32)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090215742A1,CC(C)(C)OC(=O)N1Cc2ccccc2C1C(=O)NCC(F)(F)F>>O=C(NCC(F)(F)F)C1NCc2ccccc21,,ClCCl,,Cl,,test
US03946008,COc1ccc2c3c(c(=O)oc2c1)CNCC3.ClCCN1CCOCC1>>COc1ccc2c3c(c(=O)oc2c1)CN(CCN1CCOCC1)CC3,,CCO,,CCN(CC)CC,Cl,test
US20120149910A1,Nc1c(Cl)cc(C(F)(C(F)(F)F)C(F)(F)F)cc1Cl.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>O=C(Nc1c(Cl)cc(C(F)(C(F)(F)F)C(F)(F)F)cc1Cl)c1ccc([N+](=O)[O-])cc1,,O,c1ccncc1,,,test
US20040152690A1,CC(C)(C)OC(=O)N1CCN(c2ncc(CO)cc2C(F)(F)F)CC1>>OCc1cnc(N2CCNCC2)c(C(F)(F)F)c1,,O=C(O)C(F)(F)F,,,,test
US06307056B1,COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(Br)c21.OB(O)c1ccccc1>>COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(-c3ccccc3)c21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US05576322,O=[N+]([O-])c1cc(CNc2ncnc3ccc(Cl)cc23)ccc1Cl>>Nc1cc(CNc2ncnc3ccc(Cl)cc23)ccc1Cl,[Fe],CCO,,CC(=O)O,,test
US20070185133A1,CS(=O)(=O)c1nccc(-c2ccc(S(=O)(=O)N3CCOCC3)s2)n1.NCCN1CCNC1=O>>O=C1NCCN1CCNc1nccc(-c2ccc(S(=O)(=O)N3CCOCC3)s2)n1,,Cc1ccccc1,,CCN(CC)CC,,test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cccnc3Nc3ccc(N)nc3)n2)cc1.O=C=Nc1cccc(F)c1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cccnc3Nc3ccc(NC(=O)Nc4cccc(F)c4)nc3)n2)cc1,,C1CCOC1,,,,test
US20150148313A1,Cc1cc2ccc1[C@@H](C)COC(=O)Nc1cc(F)c(OCc3ccccc3)c(c1)CN(C)C(=O)[C@@H]2Nc1ccc2c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc2c1>>Cc1cc2ccc1[C@@H](C)COC(=O)Nc1cc(F)c(O)c(c1)CN(C)C(=O)[C@@H]2Nc1ccc2c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc2c1,[Pd],CO,,,,test
US20080255202A1,CC(C)(C)OC(=O)C(C)(C)Sc1ccc(CN(Cc2ccco2)Cc2nc(Cc3ccc(F)cc3)no2)cc1.Cl>>CC(C)(Sc1ccc(CN(Cc2ccco2)Cc2nc(Cc3ccc(F)cc3)no2)cc1)C(=O)O.Cl,,C1COCCO1,,,,test
US05232917,CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](OC(=O)c5cccnc5)CC[C@]4(C)[C@H]3CC[C@]12C.CI>>CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](OC(=O)C5=CC=CN(C)C5)CC[C@]4(C)[C@H]3CC[C@]12C.[I-],,CC(C)=O,,,,test
US20150152095A1,CC(C)(C)[Si](OCCBr)(c1ccccc1)c1ccccc1.CC1(C)OB(c2cn[nH]c2)OC1(C)C>>CC1(C)OB(c2cnn(CCO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)c2)OC1(C)C,,CC#N,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130029962A1,CC(C)(C)[Si](C)(C)OCc1ccc(NC(=O)Oc2ccccc2)nc1.CC(C)(C)c1cc(CN)n(-c2cccc(Cl)c2)n1>>CC(C)(C)c1cc(CNC(=O)Nc2ccc(CO[Si](C)(C)C(C)(C)C)cn2)n(-c2cccc(Cl)c2)n1,CN(C)c1ccncc1,CC#N,CCOC(C)=O,,,test
US04965270,CCCCCC(=O)OC(=O)CCCCC.Nc1nc2c(ncn2OCCCO)c(=O)[nH]1>>CCCCCC(=O)OCCCOn1cnc2c(=O)[nH]c(N)nc21,CN(C)c1ccncc1,CN(C)C=O,,,,test
US04379154,Cl.ClCc1cccnc1.NC(N)=S>>Cl.N=C(N)SCc1cccnc1,,CCO,,,,test
US04904674,CCOC(=O)C=Cc1ccc(C=Cc2csc3ccccc23)s1>>O=C(O)C=Cc1ccc(C=Cc2csc3ccccc23)s1,,C1CCOC1,,[K+].[OH-],,test
US20150313907A1,CC(C)(C)OC(=O)NC[C@@H]1Cc2ccccc2CN1C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NC[C@@H]1Cc2ccccc2CN1,[Pd],CCOC(C)=O,,,,test
US05866612,CCN(CC)CC.CCO.NCc1ccc2c(c1)C(N)CC2>>CC(=N)NC1CCc2ccc(CN)cc21,,CCO,,Cl,Cl,test
US20130274255A1,C[Si](C)(C)CCOCn1nc(-c2ccc(Nc3cccc(F)c3)cc2)c2c1-c1ccsc1C2>>Fc1cccc(Nc2ccc(-c3n[nH]c4c3Cc3sccc3-4)cc2)c1,,CO,,Cl,,test
US20110287937A1,Cc1cc(-n2c(=O)c(C(=O)O)cc3cccnc32)no1.O=C(Cl)C(=O)Cl>>Cc1cc(-n2c(=O)c(C(=O)Cl)cc3cccnc32)no1,,ClCCl,,CN(C)C=O,,test
US05403851,NCCc1ccc(F)cc1.O=C(n1ccnc1)n1ccnc1.OCC1CCCCC1>>O=C(NCCc1ccc(F)cc1)OCC1CCCCC1,,ClCCl,,CCCCCC,CCOC(C)=O,test
US20120252853A1,Cc1cc2cc(C#N)cc(F)c2[nH]1>>Cc1cc2cc(CN)cc(F)c2[nH]1,[Ni],CO,,N,,test
US20070254877A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Fc1ccc(Br)cc1>>CC(C)(C)OC(=O)N1CCC(O)(c2ccc(F)cc2)CC1,II,C1CCOC1,,[Mg],[Cl-].[NH4+],test
US20070072862A1,COC(=O)c1cc(C(=O)Nc2cc(C(F)(F)F)ccc2F)ccc1C>>Cc1ccc(C(=O)Nc2cc(C(F)(F)F)ccc2F)cc1C(=O)O,,O,,C1CCOC1,[Li+].[OH-],test
US20040110767A1,O=C(Cl)C1CCCCC1.c1cc(OC2CCCCO2)ccc1CNc1ccc(OCCN2CCCC2)cc1>>O=C(C1CCCCC1)N(Cc1ccc(OC2CCCCO2)cc1)c1ccc(OCCN2CCCC2)cc1,,ClCCl,,CCN(CC)CC,,test
US20150299103A1,CC(C)(C)OP(=O)([O-])OC(C)(C)C.COC(=O)/C=C/C(=O)OCCl>>COC(=O)/C=C/C(=O)OCOP(=O)(OC(C)(C)C)OC(C)(C)C,,CN(C)C=O,,CCN(CC)CC,,test
US20130079320A1,C1CCOC1.CCOC(C)=O.CS(=O)(=O)NCc1ccc(CN)cc1F.c1ccncc1>>CS(=O)(=O)NCc1ccc(CNC(=O)Oc2ccccc2)cc1F,,CCOC(C)=O,,CC(C)=O,,test
US20150307497A1,CCOC(=O)c1c(OC)ccc(Br)c1CBr.Cn1cc(-c2ccc(CN)cc2)cn1>>COc1ccc(Br)c2c1C(=O)N(Cc1ccc(-c3cnn(C)c3)cc1)C2,,CCO,,O,O=C([O-])[O-].[K+].[K+],test
US05877317,O=C(O)CCC1OCCc2ccccc21>>OCCCC1OCCc2ccccc21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06011028,COC1=NCCCCC1CC1CCCCC1.[Cl-].[NH4+]>>Cl.N=C1NCCCCC1CC1CCCCC1,,CO,,,,test
US04209621,CCc1nc(N)n[nH]1.CN(C)C=CC(=O)c1cccc(C(F)(F)F)c1>>CCc1nc2nccc(-c3cccc(C(F)(F)F)c3)n2n1,,CC(=O)O,,,,test
US20140314669A1,CC(C)(C)OC(=O)C[C@H](NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1cncc(CCc2cccc(OCCF)c2)c1>>O=C(O)C[C@H](NC(=O)[C@@H]1CCCN(C(=O)CCC2CCNCC2)C1)c1cncc(CCc2cccc(OCCF)c2)c1,,O=CO,,,,test
US20080255142A1,C=CC(=O)N1CCN(c2ccc(C#N)c(F)c2)CC1.c1cc2c(cc1CC1CCCNC1)OCO2>>N#Cc1ccc(N2CCN(C(=O)CCN3CCCC(Cc4ccc5c(c4)OCO5)C3)CC2)cc1F,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US20070155805A1,CCCC(CCBr)c1sc2cc(C(F)(F)F)ccc2c1C.CCOC(=O)COc1ccc(O)cc1CC>>CCCC(CCOc1ccc(OCC(=O)OCC)c(CC)c1)c1sc2cc(C(F)(F)F)ccc2c1C,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060205767A1,COc1ccc(C(=O)CC(=O)c2ccccc2O)cc1>>COc1ccc(-c2cc(=O)c3ccccc3o2)cc1,,ClCCl,,BrB(Br)Br,CO,test
US20100173888A1,N[C@H]1CCC[C@@H](C(=O)N2CCC(O)CC2)C1.O=C(O)c1ccc(-c2cccc(F)c2)nc1>>O=C(N[C@H]1CCC[C@@H](C(=O)N2CCC(O)CC2)C1)c1ccc(-c2cccc(F)c2)nc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20040138277A1,CCOC(=O)C(CC)(Cc1ccc(O)cc1)Oc1ccccc1.Cc1ccc(S(=O)(=O)OCCc2nc(-c3cccc(-c4cccs4)c3)oc2C)cc1>>CCC(Cc1ccc(OCCc2nc(-c3cccc(-c4cccs4)c3)oc2C)cc1)(Oc1ccccc1)C(=O)O,,CCO,,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US05519161,CC(=O)CC(=O)[O-].CC1(C)OCC(CO)O1>>CC(O)CC(=O)[O-].CC1(C)OCC(CO)O1,[Ni],CCOC(C)=O,,[H][H],,test
US20080188528A1,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2.O=C(O)c1cccn(Cc2ccc(-c3ccccc3)cc2)c1=O>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)c2cccn(Cc3ccc(-c4ccccc4)cc3)c2=O)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040121965A1,CCN(C(C)C)C(C)C.CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](N)C(C)(C)C.CCOC(C)=O.CN[C@H](C(=O)O)C(C)(C)c1cccc(C(F)(F)F)c1.ClCCl.F[P-](F)(F)(F)(F)F.c1ccc2c(c1)nnn2O[P+](N1CCCC1)(N1CCCC1)N1CCCC1>>CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)(C)c1cccc(C(F)(F)F)c1)C(C)(C)C.CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](NC)C(C)(C)c1cccc(C(F)(F)F)c1)C(C)(C)C,,CCOC(C)=O,ClCCl,Cl,,test
US20160235734A1,CC(C)(C)OC(=O)NCCCNC(=O)c1cccc(C(O)(C(=O)OCC2CCN(Cc3ccccc3)CC2)c2ccccc2)c1>>NCCCNC(=O)c1cccc(C(O)(C(=O)OCC2CCN(Cc3ccccc3)CC2)c2ccccc2)c1,,C1COCCO1,,Cl,,test
US20020013460A1,CCN1CCN(c2nc(-c3ccc4c(c3)CCC4=O)cc3ccccc23)CC1>>CCN1CCN(c2nc(-c3ccc4c(c3)CCC4O)cc3ccccc23)CC1,,CO,,[BH4-].[Na+],,test
US20110015175A1,COc1cc([N+](=O)[O-])cnc1Cl.Clc1c[nH]cn1>>COc1cc([N+](=O)[O-])cnc1-n1cnc(Cl)c1,,CS(C)=O,,O,[K+].[OH-],test
US04584290,O=C(NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(C=CSc3cccnc3)CS[C@H]12)C(=O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>O=C(OC(c1ccccc1)c1ccccc1)C1=C(C=CSc2cccnc2)CS[C@@H]2C(NC(=O)C(O)c3csc(NC(c4ccccc4)(c4ccccc4)c4ccccc4)n3)C(=O)N12,,C1CCOC1,CO,Cl,[BH4-].[Na+],test
US20040087568A1,CC(C)(C)OC(=O)N1Cc2cc(N)ccc2C(C)(C)C1.CNc1nccc(C(C)Nc2ccccc2C(=O)O)n1>>CNc1nccc(C(C)Nc2ccccc2C(=O)Nc2ccc3c(c2)CN(C(=O)OC(C)(C)C)CC3(C)C)n1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20130102611A1,CC(=O)OC1CNc2nc(-c3ccccc3)c(-c3ccccc3)nc2C1OC(C)=O.CCOC(=O)CCCCCC=O>>CCOC(=O)CCCCCCN1CC(OC(C)=O)C(OC(C)=O)c2nc(-c3ccccc3)c(-c3ccccc3)nc21,,ClCCCl,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070088018A1,Clc1n[nH]c2ccccc12.O=C(NCc1ccc(F)cc1)c1ccc(S(=O)(=O)Cl)cc1>>O=C(NCc1ccc(F)cc1)c1ccc(S(=O)(=O)n2nc(Cl)c3ccccc32)cc1,,ClCCl,,CCN(CC)CC,,test
US20130331382A1,Cc1cc(B(O)O)cnc1F.Nc1ccc(Oc2ccccc2)c(Br)c1>>Cc1cc(-c2cc(N)ccc2Oc2ccccc2)cnc1F,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20100137587A1,CCOC(=O)c1cnc(C(C)(C)C)[nH]c1=O>>CC(C)(C)c1ncc(C(=O)O)c(=O)[nH]1,,CCO,,[Na+].[OH-],,test
US20090281311A1,Brc1ccc(-c2ccc(-c3ccccc3)cn2)cc1.CC(C)(C)c1ccc(-c2nc(-c3ccc(Br)cc3)nc(-c3ccc(C(C)(C)C)cc3)n2)cc1>>CC(C)(C)c1ccc(-c2nc(-c3ccc(-c4ccc(-c5ccc(-c6ccccc6)cn5)cc4)cc3)nc(-c3ccc(C(C)(C)C)cc3)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20150080362A1,CN(C)c1ccc(C(CCc2ccccc2)=NC(C)(C)C)cc1.COC=C(C(=O)OC)C(=O)OC>>COC(=O)c1cc(Cc2ccccc2)c(-c2ccc(N(C)C)cc2)[nH]c1=O,,COCCOCCOC,,,,test
US05767131,NCCCBr.O=C1NCN(c2ccccc2)C12CCNCC2>>NCCCN1CCC2(CC1)C(=O)NCN2c1ccccc1,,C1COCCO1,,Br,O=C([O-])[O-].[K+].[K+],test
US05578627,CCCC(N)COc1noc2ccccc12.Cl>>CCCC(N)COc1noc2ccccc12.Cl,,C1COCCO1,,CCOC(C)=O,,test
US20070066642A1,C[C@H](O)CN.Cc1cccc(C)c1CNc1cc(C(=O)O)cn2c(C)c(C)nc12>>Cc1cccc(C)c1CNc1cc(C(=O)NC[C@H](C)O)cn2c(C)c(C)nc12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20130338138A1,CNC(=O)c1ccc(-c2nccnc2C2CCNCC2)cc1F.Fc1ccc2nc(Cl)ccc2c1>>CNC(=O)c1ccc(-c2nccnc2C2CCN(c3ccc4cc(F)ccc4n3)CC2)cc1F,,CCOCC,O,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20140378475A1,Nc1c(F)cccc1C(=O)Nc1cccc(Br)c1Cl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=c1[nH]c2c(F)cccc2c(=O)n1-c1cccc(Br)c1Cl,,C1CCOC1,,O,,test
US20160039825A1,CCOC(=O)C1CC2CCCC(C1)N2C(=O)c1cc2n(n1)CCNC2.O=C(n1ccnc1)n1ccnc1.OCc1cc(Cl)cc(Cl)c1>>CCOC(=O)C1CC2CCCC(C1)N2C(=O)c1cc2n(n1)CCN(C(=O)OCc1cc(Cl)cc(Cl)c1)C2,,CN(C)C=O,,,,test
US20130261151A1,CC(C)CCn1c(Cn2c(=O)n(C(C)C)c3ccnc(Cl)c32)nc2cccnc21.N#C[Zn]C#N>>CC(C)CCn1c(Cn2c(=O)n(C(C)C)c3ccnc(C#N)c32)nc2cccnc21,,CN(C)C=O,,,,test
US20140051672A1,CN1C(C)(C)CC(N)CC1(C)C.Clc1ccc(Cl)nn1>>CN1C(C)(C)CC(Nc2ccc(Cl)nn2)CC1(C)C,,CCCCO,,,,test
US20140057305A1,NC(=O)c1ccc2c(c1)Sc1ccccc1N=C2Cl.OCCOCCN1CCNCC1>>NC(=O)c1ccc2c(c1)Sc1ccccc1N=C2N1CCN(CCOCCO)CC1,,CN(C)C=O,,Cc1ccccc1,,test
US20150282482A1,COC(=O)c1cc2cc(N)ccc2s1.O=C(O)c1ccccc1>>COC(=O)c1cc2cc(NC(=O)c3ccccc3)ccc2s1,CN(C)c1ccncc1,C1CCOC1,,CCN=C=NCCCN(C)C,Cl,test
US20070032530A1,O=S(Cl)Cl.OCc1ccc(-c2cccc(C(F)(F)F)c2)nc1>>FC(F)(F)c1cccc(-c2ccc(CCl)cn2)c1,,ClCCl,,CN(C)C=O,,test
US04892872,CN1C(=O)COc2c(C(=O)O)cc(Cl)cc21.O=[N+]([O-])O>>CN1C(=O)COc2c1cc(Cl)c([N+](=O)[O-])c2C(=O)O,,O=S(=O)(O)O,,,,test
US20140135318A1,CCCCc1c(-c2ccc(C(=O)NS(=O)(=O)c3ccc4ccccc4c3)cc2C(=O)N2CCc3ccccc3C2)c(C(=O)OCC)nn1-c1ccccc1>>CCCCc1c(-c2ccc(C(=O)NS(=O)(=O)c3ccc4ccccc4c3)cc2C(=O)N2CCc3ccccc3C2)c(CO)nn1-c1ccccc1,,C1CCOC1,,[BH4-].[Li+],,test
US20100158818A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(N)CN1CCOCC1>>CC(C)(CN1CCOCC1)NC(=O)OC(C)(C)C,,C1CCOC1,,,,test
US05639752,CN(C)CCc1c[nH]c2ccc(N)cc12.O=[N+]([O-])c1cnc(Cl)c([N+](=O)[O-])c1>>CN(C)CCc1c[nH]c2ccc(Nc3ncc([N+](=O)[O-])cc3[N+](=O)[O-])cc12,,C1CCOC1,,CCN(CC)CC,,test
US20130267546A1,COC(=O)c1c(OC)cc(N(C)C)nc1C>>COc1cc(C)nc(N(C)C)c1,,Cl,,O,,test
US20040138251A1,CCOC(=O)c1cnc2sccc2c1Cl>>O=C(O)c1cnc2sccc2c1Cl,,CCO,,Cl,[Na+].[OH-],test
US20120115848A1,CC[C@@H]1c2nncn2-c2cnc(-n3ccnc3Br)nc2N1C1CCCC1.O=C1NCCO1>>CC[C@@H]1c2nncn2-c2cnc(-n3ccnc3N3CCOC3=O)nc2N1C1CCCC1,[Cu]I,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=C([O-])[O-].[K+].[K+],test
US20150065482A1,COC(=O)c1nn(-c2cccc(I)c2)c2ccccc12.N>>NC(=O)c1nn(-c2cccc(I)c2)c2ccccc12,,CO,,,,test
US06251925B1,CC(C)(C)OC(=O)N(CC=O)C[C@H](O[Si](C)(C)C(C)(C)C)c1cccc(Cl)c1.COC(=O)c1cccc(-c2cccc(N)c2)c1>>COC(=O)c1cccc(-c2cccc(NCCN(C[C@H](O[Si](C)(C)C(C)(C)C)c3cccc(Cl)c3)C(=O)OC(C)(C)C)c2)c1,CC(=O)O,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04695569,ClCCl.Nc1cncnc1NCCN1CCC(Nc2nc3ccccc3n2Cc2ccc(F)cc2)CC1.S=C(Cl)Cl>>Cl.Cl.Cl.Fc1ccc(Cn2c(NC3CCN(CCn4c(=S)[nH]c5cncnc54)CC3)nc3ccccc32)cc1,,ClCCl,,CCN(CC)CC,,test
US05464840,C=CCBr.CN1CCC(=C2c3ccccc3CCc3ccccc32)CC1>>C=CCC1(C2=CCN(C)CC2)c2ccccc2CCc2ccccc21,,C1CCOC1,,[Li]CCCC,,test
US20100056515A1,CCOc1ccc(C(CC)CC)c2c1nc(Cl)n2C.Oc1ccc(Cl)cc1Br>>CCOc1ccc(C(CC)CC)c2c1nc(Oc1ccc(Cl)cc1Br)n2C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20120270863A1,CC(=O)OC(C)=O.COc1cc(/C=C/C(=O)Nc2ccccc2C(=O)O)ccc1O>>COc1cc(/C=C/c2nc3ccccc3c(=O)o2)ccc1OC(C)=O,,O,,,,test
US20150274750A1,CC(C)(C)OC(=O)N1CCNCC1.CCOC(=O)CNc1ncnc(Cl)c1[N+](=O)[O-]>>CCOC(=O)CNc1ncnc(N2CCN(C(=O)OC(C)(C)C)CC2)c1[N+](=O)[O-],,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130245355A1,C[Al](C)C.N#CCc1ccnc(Cl)c1>>Cc1cc(CC#N)ccn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20140336195A1,COc1ccc([C@H]2C[C@@H]2COc2nc3cccnc3cc2C2CCCN(C(=O)OC(C)(C)C)C2)nc1>>COc1ccc([C@H]2C[C@@H]2COc2nc3cccnc3cc2C2CCCNC2)nc1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US06140351,O=C(Nc1ccc(Cl)cc1)c1cc(Cl)ccc1NC(=O)c1scc(CCl)c1Cl.c1nc[nH]n1>>O=C(Nc1ccc(Cl)cc1)c1cc(Cl)ccc1NC(=O)c1scc(Cn2cncn2)c1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20090042892A1,Fc1ccc(C2CCC3(CC2)OCCO3)cc1Cl>>O=C1CCC(c2ccc(F)c(Cl)c2)CC1,,CC(C)=O,CCOC(C)=O,O=S(=O)(O)O,,test
US20100087431A1,C=CN1CCCC1=O.COC(=O)c1ccc(F)cc1Br>>Fc1ccc(C2=NCCC2)c(Br)c1,,C1CCOC1,O,Cl,CC(C)[N-]C(C)C.[Li+],test
US20080132540A1,CC(=O)N1CCc2ccc(N(C(=O)/C=C/c3ccccc3)C3CCNCC3)cc21.COC(=O)C(Br)c1ccccc1>>COC(=O)C(c1ccccc1)N1CCC(N(C(=O)/C=C/c2ccccc2)c2ccc3c(c2)N(C(C)=O)CC3)CC1,,CN(C)C=O,ClCCl,O,O=C([O-])[O-].[Na+].[Na+],test
US04661603,Cc1ccc(-n2ccnc2)cc1C(=O)c1c(C)cc(C(=O)O)cc1C>>Cc1ccc(-n2ccnc2)cc1C(O)c1c(C)cc(C(=O)O)cc1C,,O,,[Na+].[OH-],,test
US04148643,CC(=O)C(N=Nc1cc(S(=O)(=O)O)ccc1O)C(=O)Nc1ccccc1.CC(=O)OC(C)=O>>CC(=O)Oc1ccc(S(=O)(=O)O)cc1N=NC(C(C)=O)C(=O)Nc1ccccc1,,c1ccncc1,,,,test
US20100137317A1,CI.COc1ccc(C2=C(c3ccc(OCc4ccc5ccccc5n4)cc3)C(=O)NC2(C)C)cc1>>COc1ccc(C2=C(c3ccc(OCc4ccc5ccccc5n4)cc3)C(=O)N(C)C2(C)C)cc1,,CN(C)C=O,O,[H-].[Na+],,test
US05753657,O=c1[nH]c2c3ccccc3c(=Cc3ncc[nH]3)c2n2ccnc12>>O=c1[nH]c2c(n3ccnc13)C(Cc1ncc[nH]1)c1ccccc1-2,[Pd],CC(=O)O,,CN(C)C=O,,test
US20040121989A1,COC(=O)CCC(C)C.NN>>CC(C)CCC(=O)NN,,CO,,,,test
US20060182714A1,O=C(O)CBr.[N-]=[N+]=NCCOCCOCC(O)COCCOCCN=[N+]=[N-]>>[N-]=[N+]=NCCOCCOCC(COCCOCCN=[N+]=[N-])OCC(=O)O,,C1CCOC1,,,,test
US05045552,CCOC(=O)n1c(SCc2nccc(OCCCOC)c2C)nc2ccccc21.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)n1c(S(=O)Cc2nccc(OCCCOC)c2C)nc2ccccc21,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20080176881A1,CC(C)(C)OC(=O)N1CCC(O)CC1.Cc1cc(O)c([N+](=O)[O-])cc1Cl>>Cc1cc(OC2CCN(C(=O)OC(C)(C)C)CC2)c([N+](=O)[O-])cc1Cl,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060173019A1,COCN(c1cc(Cl)cnc1C(=O)O)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1.O=C(Cl)C(=O)Cl>>COCN(c1cc(Cl)cnc1C(=O)Cl)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1,,CN(C)C=O,ClCCl,,,test
US20070249670A1,COC(=O)C1(NC(=O)c2sc(-c3cc(F)c(F)c(F)c3)cc2N)CCCCC1.Cc1cc(C)c(N=C=O)c(C)c1>>Cc1cc(C)c(NC(=O)Nc2cc(-c3cc(F)c(F)c(F)c3)sc2C(=O)NC2(C(=O)O)CCCCC2)c(C)c1,,c1ccncc1,,CO,,test
US20060110343A1,Cc1ccc(S(=O)(=O)Cl)cc1.NCCc1ccc(O)cc1>>Cc1ccc(S(=O)(=O)NCCc2ccc(O)cc2)cc1,,C1CCOC1,,O,O=C([O-])[O-].[K+].[K+],test
US20100009986A1,CCCCC1(N(C)C)CC=C(c2[nH]c3ccc(OC(F)(F)F)cc3c2C)CC1>>CCCCC1(N(C)C)CCC(c2[nH]c3ccc(OC(F)(F)F)cc3c2C)CC1,[Pd],CCO,,,,test
US20070270587A1,NCCCN1C(=O)C2(OCCCO2)c2cc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)ccc21>>O=S(=O)(c1ccc2c(c1)C1(OCCCO1)C1=NCCCN12)N1CCC[C@H]1COc1ccccc1,,CCO,,N,,test
US05264438,CCOC(=O)Cl.Nc1cc(S(N)(=O)=O)ccc1C(=O)O>>CCOC(=O)Nc1cc(S(N)(=O)=O)ccc1C(=O)O,,[Na+],[OH-],Cl,,test
US20030207877A1,CN1C(=O)Cn2cc(C(=O)NCc3ccc(Cl)cc3)c(=O)c3cc(CCl)cc1c32.CNCC(O)c1ccccc1>>CN(Cc1cc2c3c(c1)c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn3CC(=O)N2C)CC(O)c1ccccc1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,CN(C)C=O,test
US05763437,CCOC(=O)CN1C(=O)C(NC(=O)Nc2cccc(C)c2)N=C(c2ccccc2F)c2ccccc21>>Cc1cccc(NC(=O)NC2N=C(c3ccccc3F)c3ccccc3N(CC(=O)O)C2=O)c1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20060063779A1,CC1CNCC(C)O1.O=C(Nc1ccc(Cl)c(-c2ccccn2)c1)c1ccc(Cl)nc1>>CC1CN(c2ccc(C(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)cn2)CC(C)O1,,CCCCO,,,,test
US20040259888A1,CN1CCN(c2ncnc3oc(-c4ccc(N=C(c5ccccc5)c5ccccc5)cc4)c(-c4ccc(F)cc4)c23)CC1>>CN1CCN(c2ncnc3oc(-c4ccc(N)cc4)c(-c4ccc(F)cc4)c23)CC1,[Pd],CO,,O=C[O-].[NH4+],,test
US20080070928A1,BrCc1ccccc1.CCOC(=O)c1ccc(O)c(C2CCCN2C(C)=O)c1>>CCOC(=O)c1ccc(OCc2ccccc2)c(C2CCCN2C(C)=O)c1,,[Cl-],[NH4+],CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20040224997A1,CCOC(=O)C(CCc1ccccc1)CC(=O)c1ccc(-c2ccc(N)cc2)cc1.Clc1nc2ccccc2o1>>O=C(CC(CCc1ccccc1)C(=O)O)c1ccc(-c2ccc(Nc3nc4ccccc4o3)cc2)cc1,,Cc1ccccc1,,[Na+].[OH-],,test
US20090281103A1,CCNC(=O)Oc1cc(CCCOC)cc(CN(C(=O)C(CNC(=O)OC(C)(C)C)Cc2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)c1>>CCNC(=O)Oc1cc(CCCOC)cc(CN(C(=O)C(CN)Cc2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)c1,,ClCCl,,Cl,,test
US20100144760A1,C=Cc1nc(C)ccc1-c1nc(C)c(C)o1.O=[Os](=O)(=O)=O>>Cc1ccc(-c2nc(C)c(C)o2)c(C=O)n1,O=[Os](=O)(=O)=O,C1CCOC1,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20130109682A1,CC(C)(C)[Si](C)(C)Cl.O=[N+]([O-])c1cnccc1C1CC(O)CC2(CC2)O1>>CC(C)(C)[Si](C)(C)O[C@@H]1C[C@H](c2ccncc2[N+](=O)[O-])OC2(CC2)C1,,CN(C)C=O,,O,c1c[nH]cn1,test
US20160221972A1,COC(=O)c1ccc2c(c1)OCCNC2=O.COc1ccc(CBr)cc1>>COC(=O)c1ccc2c(c1)OCCN(Cc1ccc(OC)cc1)C2=O,,CN(C)C=O,,[H-].[Na+],,test
US05677464,CS(=O)(=O)Cl.C[C@@H](n1ccn(-c2ccc(OC(F)(F)C(F)F)cc2)c1=O)[C@](O)(CO)c1ccc(F)cc1F>>C[C@@H](n1ccn(-c2ccc(OC(F)(F)C(F)F)cc2)c1=O)[C@](O)(COS(C)(=O)=O)c1ccc(F)cc1F,,CCN(CC)CC,CCOC(C)=O,,,test
US20130150359A1,COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1O.NC(=O)C(Br)c1ccc(F)cc1>>COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OC(C(N)=O)c1ccc(F)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20030045560A1,CCCc1c(C(=O)Cl)cnn1-c1ccccc1.COC(=O)COc1ccc2cc(C[NH3+])ccc2c1Br>>CCCc1c(C(=O)NCc2ccc3c(Br)c(OCC(=O)OC)ccc3c2)cnn1-c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20090105234A1,CC(C)(O)c1cccc(I)c1.CCOC(=O)C(F)(F)Br>>CCOC(=O)C(F)(F)c1cccc(C(C)(C)O)c1,[Cu],CS(C)=O,,,,test
US20150214492A1,CC1(C)C=C(B2OC(C)(C)C(C)(C)O2)C=C2C=c3cc4c5ccccc5c5ccccc5c4cc3=C21.O=[N+]([O-])c1ccccc1Br>>CC1(C)C=C(c2ccccc2[N+](=O)[O-])C=C2C=c3cc4c5ccccc5c5ccccc5c4cc3=C21,,Cc1ccccc1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US05591862,Cc1oc(-c2ccccc2)nc1CCOc1ccc(C=O)cc1>>Cc1oc(-c2ccccc2)nc1CCOc1ccc(CO)cc1,,CCO,,CC(=O)O,[BH4-].[Na+],test
US20090005353A1,Cc1cccc(C)c1OC(=O)CCCNC(=O)OC(C)(C)C.Cl>>Cc1cccc(C)c1OC(=O)CCCN.Cl,,ClCCl,,,,test
US20100331314A1,CC(C)CNc1ccn2ncc(C=O)c2n1.O=C1CNC(=O)N1>>CC(C)CNc1ccn2ncc(C=C3NC(=O)NC3=O)c2n1,,CC#N,,C1CCNCC1,,test
US20110021489A1,O=C(N1CCOCC1)N1CC(c2ccc(C(F)(F)F)cc2)CC(c2nc(Cl)no2)C1.OCC(F)(F)F>>O=C(N1CCOCC1)N1CC(c2ccc(C(F)(F)F)cc2)CC(c2nc(OCC(F)(F)F)no2)C1,,C1COCCO1,,,,test
US20140275084A1,Clc1ccccc1CCBr.NC(=O)c1ccnc(-c2c[nH]cn2)c1>>NC(=O)c1ccnc(-c2cn(CCc3ccccc3Cl)cn2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05665732,CC(=O)OC(C)=O.Cc1n[nH]c2cc(F)ccc12>>CC(=O)n1nc(C)c2ccc(F)cc21,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20110118322A1,COC(=O)c1cccc(COc2ccc(I)cc2)c1.COc1cc(F)c(F)cc1B(O)O>>COC(=O)c1cccc(COc2ccc(-c3cc(F)c(F)cc3OC)cc2)c1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20050096380A1,BrCC1CC1.CC(C)C1=CCC(C)(C)c2cc(O)c(Br)cc21>>CC(C)C1=CCC(C)(C)c2cc(OCC3CC3)c(Br)cc21,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100178291A1,CC(C)(C)OC(=O)N1C[C@@H](c2cn3c4c(cccc24)CCC3)[C@H](c2c[nH]c3ccccc23)C1.Cl>>Cl.c1ccc2c([C@@H]3CNC[C@H]3c3cn4c5c(cccc35)CCC4)c[nH]c2c1,,ClCCl,,C1COCCO1,,test
US05192766,COc1cc(C(=O)Cl)cc(OC)c1OC.COc1ccc(C(=CC(=S)N2CCNCC2)c2ccc(OC)cc2)cc1>>COc1ccc(C(=CC(=S)N2CCN(C(=O)c3cc(OC)c(OC)c(OC)c3)CC2)c2ccc(OC)cc2)cc1,,ClCCl,,CCN(CC)CC,O,test
US20050267133A1,CC(C)(C)OC(=O)N1CCC(/C=N/Nc2ncnc3c2cnn3-c2ccccc2)CC1.O=C(O)C(F)(F)F>>C(=NNc1ncnc2c1cnn2-c1ccccc1)C1CCNCC1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20150111885A1,CCS(=O)(=O)Cl.Cn1cc(-c2cc(N)ccc2Oc2ccc(F)cc2F)c(F)cc1=O>>CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(-c2cn(C)c(=O)cc2F)c1,,ClCCl,,Cl,c1ccncc1,test
US20080269192A1,CC(=O)OCCC(C)n1c(COC(C)=O)nc2cnc3cc(Br)ccc3c21>>CC(CCO)n1c(CO)nc2cnc3cc(Br)ccc3c21,,CO,,O,[Li+].[OH-],test
US20130259850A1,CCOC(=O)Cc1ccc(C)c(OCc2c(C)cccc2C)c1>>Cc1ccc(CC(=O)O)cc1OCc1c(C)cccc1C,,CCO,,Cl,[Na+].[OH-],test
US20080103123A1,CC(C)(C)OC(=O)N1CCC(OCc2ccc(-c3ccc(S(C)(=O)=O)cc3)nc2)CC1>>CS(=O)(=O)c1ccc(-c2ccc(COC3CCNCC3)cn2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120046244A1,CC(C)=CCC/C(C)=C/CO.ClCCl.O=C1CCC(=O)O1>>CC(C)=CCC/C(C)=C/COC(=O)CCl,CN(C)c1ccncc1,,,c1ccncc1,,test
US05578627,COc1cccc(C(N)COc2noc3ccc(Cl)cc23)c1>>NC(COc1noc2ccc(Cl)cc12)c1cccc(O)c1,,ClCCl,,BrB(Br)Br,,test
US20100190745A1,CCOC=C(C(=O)OCC)C(=O)OCC.Nc1cccc(I)c1>>CCOC(=O)C(=CNc1cccc(I)c1)C(=O)OCC,,Cc1ccccc1,,,,test
US20120157452A1,CO.COc1ccc(Br)c(C(=O)O)c1F>>COC(=O)c1c(Br)ccc(OC)c1F,,CO,,C[Si](C)(C)C=[N+]=[N-],,test
US20040048868A1,CCCC(C(=O)c1nc2cc(C)ccc2[nH]1)=C(SC)SC.NN>>CCCc1c(-c2nc3cc(C)ccc3[nH]2)n[nH]c1SC,,CCO,,O,,test
US20080300232A1,O=C(COc1cccc(Cl)c1)NC1CCNCC1.O=Cc1ccc(-c2ccccn2)cc1>>O=C(COc1cccc(Cl)c1)NC1CCN(Cc2ccc(-c3ccccn3)cc2)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150126498A1,CCN1CCCC(Cl)C1.Cc1noc(C)c1CCN1C(=O)N(Cc2c(F)cccc2F)c2ccccc2S1(=O)=O>>CCN1CCCC(N2C(=O)N(Cc3c(F)cccc3F)c3ccccc3S2(=O)=O)C1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20160168156A1,O=C(O)/C=C/c1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12.O=C1CNCCN1>>O=C1CN(C(=O)/C=C/c2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CCN1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050004373A1,CC1(C)CCSc2ccc(C(Cl)=CC=O)cc21>>C#Cc1ccc2c(c1)C(C)(C)CCS2,,C1COCCO1,,O,[Na+].[OH-],test
US03935314,Cl.Cl.Clc1ccc2nc(NC3=NCCN3)[nH]c2c1>>Cl.Clc1cc2nc(NC3=NCCN3)[nH]c2cc1Cl,,Cl,,OO,,test
US20150087646A1,C#Cc1ccc(-n2nc(-c3c(F)cccc3Cl)[nH]c2=O)cc1.FC(F)(F)c1ccccc1I>>O=c1[nH]c(-c2c(F)cccc2Cl)nn1-c1ccc(C#Cc2ccccc2C(F)(F)F)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CS(C)=O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100003260A1,CCOC(=O)CP(=O)(OCC)OCC.O=CC=Cc1c(F)cccc1F>>CCOC(=O)C=CC=Cc1c(F)cccc1F,,C1CCOC1,,[H-].[Na+],,test
US20030207863A1,NCCN1CCCC1.O=C(O)c1cccc(Br)c1>>O=C(NCCN1CCCC1)c1cccc(Br)c1,,CN(C)C=O,O,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20150274777A1,COc1ccc(C[C@H](NC(=O)[C@@H](NC(=O)C2Cc3ccccc3C2)C2CC2)C(=O)N[C@@H](Cc2ccccc2)C(O)C(=O)NCc2ccccc2)cc1>>COc1ccc(C[C@H](NC(=O)[C@@H](NC(=O)C2Cc3ccccc3C2)C2CC2)C(=O)N[C@@H](Cc2ccccc2)C(=O)C(=O)NCc2ccccc2)cc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20050228004A1,CN(C)C=Nc1cccn2c(-c3ccnc(NC4CCCC4)n3)c(-c3ccc(F)cc3)nc12>>Nc1cccn2c(-c3ccnc(NC4CCCC4)n3)c(-c3ccc(F)cc3)nc12,,CO,,[Na+].[OH-],,test
US20140350002A1,CS(=O)(=O)Cl.Cn1c(=O)n(CC(C)(C)C)c2ccc(C3=CC4CNCC4C3)nc21>>Cn1c(=O)n(CC(C)(C)C)c2ccc(C3=CC4CN(S(C)(=O)=O)CC4C3)nc21,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05360802,CC(C)(C)C(=O)NS(=O)(=O)c1cccc(N)c1.CN1C(=O)C(NC(=O)Oc2ccc([N+](=O)[O-])cc2)N=C(C2CCCCC2)c2ccccc21>>CN1C(=O)C(NC(=O)Nc2cccc(S(=O)(=O)NC(=O)C(C)(C)C)c2)(C2CCCCC2)N=Cc2ccccc21,,CO,,CCN(CC)CC,CN(C)C=O,test
US20030176454A1,Brc1cccc2cnccc12.OB(O)c1ccccc1>>c1ccc(-c2cccc3cnccc23)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20100010007A1,CC(C)(C)OC(=O)N1CCC(Nc2c[n+]([O-])ccc2[N+](=O)[O-])CC1.COC(OC)OC>>CC(C)(C)OC(=O)N1CCC(n2cnc3ccncc32)CC1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040266644A1,CCCCCCCCNCCCCCCCC.N#CCCl>>CCCCCCCCN(CC#N)CCCCCCCC,,CO,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20030162840A1,CC1(C)OCc2cc([C@@H](O)CN[C@H](CO)c3ccccc3)ccc2O1.O=CCCCCCOCCCCc1ccccc1>>CC1(C)OCc2cc([C@@H](O)CN(CCCCCCOCCCCc3ccccc3)[C@H](CO)c3ccccc3)ccc2O1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070117866A1,CC(C)(C)C(=O)Cl.COC(=O)[C@@H](O)Cc1cccc(O)c1>>COC(=O)[C@@H](O)Cc1cccc(OC(=O)C(C)(C)C)c1,,COC(C)(C)C,,CCN(CC)CC,Cl,test
US20140094495A1,CC(C)(C)OCl.CN1CC(C)(CCl)NC1=O>>CN1CC(C)(CCl)N(Cl)C1=O,,CO,,,,test
US20090142297A1,CC(C)(C)O.COC(=O)CCCCC(=O)O>>COC(=O)CCCCC(=O)OC(C)(C)C,,CCOCC,CN(C)C=O,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US03962249,C[C@H]1CN[C@H](C)CN1CCCc1ccccc1.O=C(Cl)c1ccco1>>C[C@H]1CN(C(=O)c2ccco2)[C@H](C)CN1CCCc1ccccc1.Cl,,c1ccccc1,,,,test
US05189023,CC(=O)NCCO.O=[PH](O)CCCc1ccccc1>>CC(=O)NCCO[PH](=O)CCCc1ccccc1,CN(C)c1ccncc1,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20100215579A1,FCCOCCOCCCl.Oc1ccc(I)cc1>>FCCOCCOCCOc1ccc(I)cc1,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20030212276A1,CN1CCC(CCCN)CC1.COc1cc2c(Nc3cc(OC)c(Cl)cc3Cl)c(C#N)cnc2cc1F>>COc1cc(Nc2c(C#N)cnc3cc(NCCCC4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl,,CN1CCCC1=O,,,,test
US20150065507A1,Cc1nc(Br)ccc1[N+](=O)[O-].NCCO>>Cc1nc(NCCO)ccc1[N+](=O)[O-],,CCO,,,,test
US04496572,O=C1CCCc2ccc(Br)cc21.O=Cc1cccnc1>>O=C1C(=Cc2cccnc2)CCc2ccc(Br)cc21,,CC(=O)O,,C1CCNCC1,,test
US20060079533A1,O=C(OCC(Cl)(Cl)Cl)N1CCC(c2ccc(Cl)cc2)C(OCc2ccc3ccccc3c2)C1>>Clc1ccc(C2CCNCC2OCc2ccc3ccccc3c2)cc1,[Zn],CC(=O)O,O,,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](O[Si](C)(C)C(C)(C)C)CC2)c2c(F)cnn12.CCOC(C)=O>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(=O)OCC)CC2)c2c(F)cnn12,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20140005164A1,Cn1c(=O)n(C[C@@H]2CC[C@@H](C(=O)O)CC2)c2[nH]c(=O)ccc21.Nc1cccnn1>>Cn1c(=O)n(C[C@@H]2CC[C@@H](C(=O)Nc3ccnnc3)CC2)c2[nH]c(=O)ccc21,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20060211709A1,CNC(=O)c1nc(-c2cccc(C=O)c2)cnc1N.Nc1ccccc1N>>CNC(=O)c1nc(-c2cccc(-c3nc4ccccc4[nH]3)c2)cnc1N,,CN1CCCC1=O,,,,test
US20150031540A1,Cn1ncc(-n2nc(Cl)c3ccccc32)c(-n2nc(Cl)c3ccccc32)c1=O.O>>CN1N=CC(=O)C(n2nc(Cl)c3ccccc32)C1=O,,CO,,[Na+].[OH-],,test
US05576321,O=[N+]([O-])c1ccc2c(C3=CCNCC3)c[nH]c2c1.c1cc(OC[C@@H]2CO2)c2cc[nH]c2c1>>O=[N+]([O-])c1ccc2c(C3=CCN(C[C@H](O)COc4cccc5[nH]ccc45)CC3)c[nH]c2c1,,CS(C)=O,,,,test
US20080027067A1,Brc1ccccc1.O=C1CN(Cc2ccccc2)CCN1>>O=C1CN(Cc2ccccc2)CCN1c1ccccc1,[Cu]I,,,O=C([O-])[O-].[K+].[K+],,test
US20130085127A1,CCOC(=O)c1ccnc(CCl)c1.COc1ccc(C(OC2CCNCC2)c2ccccc2)cc1>>CCOC(=O)c1ccnc(CN2CCC(OC(c3ccccc3)c3ccc(OC)cc3)CC2)c1,,O,,CC#N,CCN(CC)CC,test
US05612337,CN(C)Cc1[nH]nnc1CN1CCO[C@H](O[C@H](CO[Si](C)(C)C(C)(C)C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H]1c1ccc(F)cc1>>CN(C)Cc1[nH]nnc1CN1CCO[C@H](O[C@H](CO)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H]1c1ccc(F)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090238808A1,CC(C)(C)OC(=O)NCc1ccc(N)cc1.Fc1cnc(Cl)nc1Nc1ccccc1>>CC(C)(C)OC(=O)NCc1ccc(Nc2ncc(F)c(Nc3ccccc3)n2)cc1,,CO,ClCCl,,,test
US20130237573A1,CCOC(=O)[C@H]1[C@H]2[C@@H]1[C@](NC(=O)OC(C)(C)C)(C(=O)OCC)[C@H](OCc1ccc(Cl)c(Cl)c1)[C@H]2NC(=O)COC(C)=O>>CC(C)(C)OC(=O)N[C@@]1(C(=O)O)[C@H](OCc2ccc(Cl)c(Cl)c2)[C@@H](NC(=O)CO)[C@@H]2[C@H]1[C@H]2C(=O)O,,C1CCOC1,,Cl,[Li+].[OH-],test
US20080242675A1,Cc1cnc(N2CCN(C)CC2)cc1CC(=O)OC(C)(C)C.N>>Cc1cnc(N2CCN(C)CC2)cc1CC(N)=O,,ClCCl,O=C(O)C(F)(F)F,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US20130029963A1,N=C(N)NN.O=CC(=O)c1ccccn1>>Nc1nncc(-c2ccccn2)n1,,CCO,,O=C(O)O,,test
US20150166505A1,COc1ccnc(OC)c1.O=C1CCC(=O)N1Br>>COc1cc(OC)c(Br)cn1,,CC#N,,,,test
US20070276011A1,COC(=O)c1ccc(CBr)cc1.O=C1NC(=O)C(=Cc2ccc(O)c(C(=O)OCc3ccccc3)c2)S1>>COC(=O)c1ccc(CN2C(=O)SC(=Cc3ccc(O)c(C(=O)OCc4ccccc4)c3)C2=O)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080312216A1,CI.O=C1OCCC1c1ccc(Cl)c(Cl)c1>>CC1(c2ccc(Cl)c(Cl)c2)CCOC1=O,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US06255276B1,O=C(O)CCCCCCC/C=C\CCCCCCBr>>O=C1CCCCCCCC=CCCCCCCO1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20070270437A1,COC(=O)c1sc([N+](=O)[O-])cc1O.C[C@H](O)c1ccccc1C(F)(F)F>>COC(=O)c1sc([N+](=O)[O-])cc1O[C@H](C)c1ccccc1C(F)(F)F,,ClCCl,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130267546A1,BrCc1ccccc1.Cc1nc(-n2c(C)ccc2C)nc(C)c1O>>Cc1nc(-n2c(C)ccc2C)nc(C)c1OCc1ccccc1,,C1CCOC1,,O,[H-].[Na+],test
US05637729,CI.CSC1=NC(C)(c2ccccc2)C(=O)N1Nc1ccccc1>>CSC1=NC(C)(c2ccccc2)C(=O)N1N(C)c1ccccc1,,C1CCOC1,,O,CC(C)(C)[O-].[K+],test
US20160002225A1,CC(=O)OC(CO)COc1ccccc1.COc1ccc(Cn2nc(I)c3c(Cl)ccnc32)cc1>>COc1ccc(Cn2nc(I)c3c(OCC(O)COc4ccccc4)ccnc32)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080171743A1,CS(=O)(=O)Cl.C[C@H]1COCCN1c1cc(CO)nc(-c2ccc(NC(=O)N(C)C)cc2)n1>>C[C@H]1COCCN1c1cc(COS(C)(=O)=O)nc(-c2ccc(NC(=O)N(C)C)cc2)n1,,ClCCl,,CCN(CC)CC,,test
US20040209902A1,CCOC(=O)CC(C)=O.Cc1ccc(N)cc1>>CCOC(=O)C=C(C)Nc1ccc(C)cc1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100160322A1,CC(=O)O.CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N)CC1.CCOC1(O[Si](C)(C)C)CC1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N(C2CC2)C2CC2)CC1,,CO,,[BH3-]C#N.[Na+],,test
US20100190747A1,CC(Cl)C(=O)Cl.N#CCCN>>CC(Cl)C(=O)NCCC#N,,C1CCOC1,,CCN(CC)CC,CCOCC,test
US20130053565A1,C=C(C)C#CCC.CC(C)(C)OC(=O)N1CC(=O)C1>>C=C(C)C1=C(CC)C(=O)CN(C(=O)OC(C)(C)C)C1,,Cc1ccccc1,,,,test
US20070149561A1,CC(=O)OC(C)=O.CNCCn1cc(-c2ccnc3[nH]c(-c4cccc(CN(C)C)c4)cc23)c(-c2ccc(NC(=O)N(C)C)cc2)n1>>CC(=O)N(C)CCn1cc(-c2ccnc3[nH]c(-c4cccc(CN(C)C)c4)cc23)c(-c2ccc(NC(=O)N(C)C)cc2)n1,,CO,O,[Na+].[OH-],,test
US20110105562A1,CC(C)(C)OC(=O)N1CCC(O)CC1.COc1cc(O)cc(Br)c1>>COc1cc(Br)cc(OC2CCN(C(=O)OC(C)(C)C)CC2)c1,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050228017A1,CC(C)(C)OC(=O)COc1cc(CNCCc2ccccn2)ccc1OCc1ccccc1.O=C(Cl)CCCCc1ccccc1>>CC(C)(C)OC(=O)COc1cc(CN(CCc2ccccn2)C(=O)CCCCc2ccccc2)ccc1OCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20140008570A1,C1CCOC1.CC1(C)OB(c2ccc(OCCO)cc2)OC1(C)C.CCOCC.Oc1cc(Br)cc(Br)c1>>OCCOc1ccc(-c2cc(O)cc(-c3ccc(OCCO)cc3)c2)cc1,,C1CCOC1,,Cl,O,test
US04652089,COC=C1CCC(c2ccc(C#N)cc2)CC1>>N#Cc1ccc([C@@H]2CC[C@@H](C=O)CC2)cc1,,O,,C1CCOC1,,test
US20160108037A1,CCOC(=O)c1ccc(C(F)(F)F)n2c(N(C)CCOC)nnc12>>COCCN(C)c1nnc2c(C(=O)O)ccc(C(F)(F)F)n12,,CCO,,[Na+].[OH-],,test
US20150018422A1,CCOC(=O)COc1cccc(CO)c1.CS(=O)(=O)Cl>>CCOC(=O)COc1cccc(COS(C)(=O)=O)c1,,C1CCOC1,,CCN(CC)CC,O,test
US04413010,CCOC(=O)NCC(C)O.CS(=O)(=O)Cl>>CCOC(=O)NCC(C)OS(C)(=O)=O,,CCN(CC)CC,,Cl,,test
US20130244958A1,COc1cc(C(=O)OC(CC(=O)OCc2ccccc2)OC(N)=O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F>>COc1cc(C(=O)OCOC(=O)NCC(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F,[Pd],CCOC(C)=O,,[H][H],,test
US05846982,CN1CC=C(c2c[nH]c3ccc(C4CN=CS4)cc23)CC1>>CN1CCC(c2c[nH]c3ccc(C4CN=CS4)cc23)CC1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20130184493A1,O=C(Cc1ccccc1)c1ccc(F)cc1.O=S(=O)(Cl)Cl>>O=C(c1ccc(F)cc1)C(Cl)c1ccccc1,,ClCCl,,,,test
US05034417,CCOC(=O)c1ccc([N+](=O)[O-])c(Sc2ccc(F)cc2F)c1>>CCOC(=O)c1ccc(N)c(Sc2ccc(F)cc2F)c1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20080139558A1,CC(C)(C)OC(=O)n1ccc2ccccc21.Cc1ncsc1Br>>Cc1ncsc1-c1cc2ccccc2n1C(=O)OC(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20100261771A1,C=CCn1c(-c2ccc(Cl)cc2Br)n[nH]c1=O.COC(=O)CCl>>C=CCn1c(-c2ccc(Cl)cc2Br)nn(CC(=O)OC)c1=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US06130217,ClCc1ccncc1.NC(=NO)c1cccc(O)c1>>Oc1cccc(-c2noc(-c3ccncc3)n2)c1,,c1ccncc1,,Cl,,test
US05364767,CC(=O)Nc1cc(Cl)ccc1C(=O)O>>Nc1cc(Cl)ccc1C(=O)O,,Cl,,,,test
US06340687B1,Cc1cc(Cl)ccc1N.OCCCBr>>Cc1cc(Cl)ccc1NCCCO,,ClCCl,,,,test
US20120264923A1,CC(=CCCCO)CCCC(C)CCCC(C)CCCC(C)C.CC(=O)OC[C@H]1O[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>CC(=O)OC[C@H]1OC(OCCCC=C(C)CCCC(C)CCCC(C)CCCC(C)C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,CC#N,CCOC(C)=O,CCN(CC)CC,,test
US20050182269A1,N#Cc1cc(Br)c2c(c1)CCCC2>>N#Cc1cc(Br)c2ccccc2c1,[Pd],,,,,test
US03941785,CC(=O)Cl.CCCc1nc(C)c2n1N=C(NCC)NC2>>CCCc1nc(C)c2n1N=C(N(CC)C(C)=O)NC2.Cl,,CC(=O)O,,,,test
US20080161322A1,CC(C)(C)c1nc(N2CCN(CCCCl)CC2)cc(C(F)(F)F)n1.O=C1CCc2ccccc2N1>>CC(C)(C)c1nc(N2CC[NH+](CCCN3C(=O)CCc4ccccc43)CC2)cc(C(F)(F)F)n1.[Cl-],,CN(C)C=O,,[H-].[Na+],,test
US20130210844A1,CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)O)c1F.CC(C)Oc1ncnc2c(N)cccc12>>CC(C)Oc1ncnc2c(NC(=O)c3c(Cl)ccc(CNC(=O)C(C)(C)C)c3F)cccc12,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20120027874A1,CC(C)n1cc(-c2cnc(N)c(-c3nnc(-c4cccc(CBr)c4)o3)n2)ccc1=O.CN>>CNCc1cccc(-c2nnc(-c3nc(-c4ccc(=O)n(C(C)C)c4)cnc3N)o2)c1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US05493053,CC(C)(C)OC(=O)ON=C(C#N)c1ccccc1.NCCCCCNOCc1ccccc1>>CC(C)(C)OC(=O)NCCCCCNOCc1ccccc1,,C1CCOC1,,Cl,Cl,test
US20110207698A1,N#Cc1c(Cl)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1cc[nH]n1.NCCO>>N#Cc1c(NCCO)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1cc[nH]n1,,C1CCOC1,,CO,,test
US04236012,O=C(OO)c1ccccc1.O=C(OOC(=O)c1ccccc1)c1ccccc1>>C1=C(CCc2ccccc2)O1,,ClC(Cl)Cl,,,,test
US20070142380A1,CN(C)C=O.O=C(O)c1ccc2c(C3CCCCC3)c[nH]c2c1>>COC(=O)c1ccc2c(C3CCCCC3)c[nH]c2c1,,O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20130274483A1,FC(F)(F)c1cccnc1CBr.O=C1Nc2ccccc2[C@]12COc1cc3c(cc12)OCCO3>>O=C1N(Cc2ncccc2C(F)(F)F)c2ccccc2[C@]12COc1cc3c(cc12)OCCO3,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120004270A1,Cc1c(N[C@@H](c2nnc(-c3ccc(C#N)cc3)o2)[C@H](OCc2ccccc2)C(F)(F)F)ccc(C#N)c1Cl>>Cc1c(N[C@@H](c2nnc(-c3ccc(C#N)cc3)o2)[C@H](O)C(F)(F)F)ccc(C#N)c1Cl,,ClCCl,,BrB(Br)Br,,test
US06399773B1,C=Cc1ccc([N+](=O)[O-])cc1C.O=[O+][O-]>>Cc1cc([N+](=O)[O-])ccc1C=O,,ClCCl,,,,test
US20140249104A1,CC(C)(C)[S@@](=O)N[C@@](CF)(C[C@H](O)C(F)(F)F)c1cccc(Br)c1>>N[C@@](CF)(C[C@H](O)C(F)(F)F)c1cccc(Br)c1,,Cl,ClCCl,C1COCCO1,[Na+].[OH-],test
US20150259316A1,COC(=O)CC(=O)c1ccc(C(C)(C)C)cc1.COc1cc(O)c(C=O)c(OC)c1>>COc1cc(OC)c2cc(C(=O)c3ccc(C(C)(C)C)cc3)c(=O)oc2c1,,CCO,,C1CCNCC1,,test
US20070225267A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OC[C@@H](NC[C@@H](O)CCC1CCCCC1)[C@@H](OCc1ccccc1)[C@H](Cc1cc(F)cc(F)c1)N(Cc1ccccc1)Cc1ccccc1>>CC(C)(C)OC(=O)N(C[C@@H](O)CCC1CCCCC1)[C@H](CO)[C@@H](OCc1ccccc1)[C@H](Cc1cc(F)cc(F)c1)N(Cc1ccccc1)Cc1ccccc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US04948795,O=C(O)C1CSC(c2cccnc2)N1.c1cncc(CCCN2CCNCC2)c1>>O=C(C1CSC(c2cccnc2)N1)N1CCN(CCCc2cccnc2)CC1,,CCOC(C)=O,CN(C)C=O,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20090324569A1,C1CCC2=NCCCN2CC1.COc1ccc(Cc2ccc(F)nc2)cc1-c1cccc(Cl)c1.ClCCl.O=[N+]([O-])c1cccc(B(O)O)c1>>COc1ccc(Cc2ccc(N3CCC(O)C3)nc2)cc1-c1cccc(Cl)c1,,ClCCl,,,,test
US04045209,CN(C(=O)Cl)S(C)(=O)=O.Nc1cccc(C(F)(F)F)c1>>CN(C(=O)Nc1cccc(C(F)(F)F)c1)S(C)(=O)=O,,C1CCOC1,,CCN(CC)CC,,test
US08778939B2,COC(=O)c1ccc(Br)cc1O.C[C@@H](O)c1ccccc1>>COC(=O)c1cc(Br)ccc1O[C@@H](C)c1ccccc1,,ClCCl,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080280875A1,C1CNC1.O=C(Cl)c1ccc(F)cc1F>>O=C(c1ccc(F)cc1F)N1CCC1,,ClCCl,,CCN(CC)CC,Cl,test
US20110135601A1,CN(C)C=O.O=C(O)C1CCc2ccccc2C1>>CN(C)C(=O)C1CCc2ccccc2C1,,ClC(Cl)Cl,,O=C(Cl)C(=O)Cl,,test
US20120115895A1,CC(C)(C)OC(=O)CN1C(=O)C2(NC(=O)NC2=O)c2cc(Cl)ccc21.CI>>CN1C(=O)NC(=O)C12C(=O)N(CC(=O)OC(C)(C)C)c1ccc(Cl)cc12,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20160016948A1,BrCCOC1CCCCO1.CC(C)n1c(CO)nc2cnc(Br)cc21>>CC(C)n1c(COCCOC2CCCCO2)nc2cnc(Br)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20090156642A1,CN(Cc1cc(S(=O)(=O)c2ccccn2)n(-c2ccccc2Cl)n1)C(=O)OC(C)(C)C.Cl>>CNCc1cc(S(=O)(=O)c2ccccn2)n(-c2ccccc2Cl)n1.Cl,,CCO,,CCOC(C)=O,,test
US20100029650A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(O)C1CCNCC1>>CC(O)C1CCN(C(=O)OC(C)(C)C)CC1,,ClCCCl,,CCN(CC)CC,,test
US05288693,C=CC(=O)c1cc(OC)ccc1OC>>C=CC(=O)C1=CC(=O)C=CC1=O,,CC#N,O,,,test
US05939405,O=c1oc(-c2ccc(C(F)(F)F)cc2)nn1Cc1cc(Cl)ccc1OP(=O)(OCc1ccccc1)OCc1ccccc1>>O=c1oc(-c2ccc(C(F)(F)F)cc2)nn1Cc1cc(Cl)ccc1OP(=O)(O)O,[Pd],CCO,CCOC(C)=O,,,test
US06300342B1,N#Cc1ccc(CCC(=O)N2CCCc3cc(NC(=O)C(F)(F)F)ccc32)cc1>>N#Cc1ccc(CCC(=O)N2CCCc3cc(N)ccc32)cc1,,CO,,C1COCCO1,[Na+].[OH-],test
US07217717B2,C=CCc1c(OC)c(OC)cc2ncnc(Nc3ccc(Br)cc3F)c12.II>>COc1cc2ncnc3c2c(c1OC)CC(CI)N3c1ccc(Br)cc1F,,ClC(Cl)Cl,ClCCl,,,test
US20090176779A1,CC(C)(C)OC(=O)n1nc(N)c2nc(C(=O)NC(C)(C)c3ccccc3)sc21.COc1ccc(C(=O)Cl)cc1>>COc1ccc(C(=O)Nc2nn(C(=O)OC(C)(C)C)c3sc(C(=O)NC(C)(C)c4ccccc4)nc23)cc1,,C1CCOC1,c1ccncc1,[Cl-].[Na+],,test
US20060281727A1,CC(C)(C)OC(=O)N[C@H](C(=O)N1CC[C@H](F)C1)[C@H]1CCc2cc(-c3ccc(F)cc3)ccc21.Cl>>Cl.N[C@H](C(=O)N1CC[C@H](F)C1)[C@H]1CCc2cc(-c3ccc(F)cc3)ccc21,,C1COCCO1,,,,test
US20150133457A1,C=CC(=O)Cl.COc1cnc(Nc2ccc(N3CCN(C)CC3)cc2)nc1Oc1cccc(N)c1>>C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(C)CC4)cc3)ncc2OC)c1,,C1CCOC1,CO,CCN(C(C)C)C(C)C,,test
US20040053942A1,CCCCI.Oc1ccn2nc(-c3ccc(F)cc3)c(-c3ccncc3)c2c1>>CCCCOc1ccn2nc(-c3ccc(F)cc3)c(-c3ccncc3)c2c1,,C1CCOC1,CN(C)C=O,O,CC(C)(C)[O-].[K+],test
US20050215577A1,CI.COC(=O)C(C1CCCC(=O)C1)S(=O)(=O)c1ccccc1>>COC(=O)C(C)(C1CCCC(=O)C1)S(=O)(=O)c1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US20120302586A1,CCc1nc2nc(C)cc(Cl)n2n1.Nc1ccc(S(F)(F)(F)(F)F)cc1>>CCc1nc2nc(C)cc(Nc3ccc(S(F)(F)(F)(F)F)cc3)n2n1,,CCO,,,,test
US20130196002A1,CCOC(=O)COCc1ccccc1.CCOC=O>>CCOC(=O)C(C=O)OCc1ccccc1,,CCOCC,,[H-].[Na+],,test
US20130060043A1,CC(C)(C)OC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)ccn1>>O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1ccc(Oc2ccnc(C(=O)O)c2)cc1F,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20060154926A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COCCCOc1cc(C[C@@H](C[C@H](N)[C@@H]2C[C@@H](C(C)C)C(=O)O2)C(C)C)ccc1OCCCO>>COCCCOc1cc(C[C@@H](C[C@H](NC(=O)OC(C)(C)C)[C@@H]2C[C@@H](C(C)C)C(=O)O2)C(C)C)ccc1OCCCO,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120077781A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCNCc3ccc(Cl)c(Cl)c3)c2cc1C>>Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCN(Cc3ccc(Cl)c(Cl)c3)C(=O)OC(C)(C)C)c2cc1C,,CO,,CCN(CC)CC,,test
US04873255,C=CC(=O)OCC.Cc1cc(C)c2c(c1)OC(C)(COc1ccc(N)cc1)CC2.Cl>>CCOC(=O)C(Cl)Cc1ccc(OCC2(C)CCc3c(C)cc(C)cc3O2)cc1,,CC(C)=O,O,O=N[O-].[Na+],,test
US04457931,BrP(Br)Br.CC(CO)N1CCN(c2ccccn2)CC1>>CC(CBr)N1CCN(c2ccccn2)CC1,,ClC(Cl)Cl,,O,,test
US20150291595A1,COc1ccc(S(=O)(=O)n2ccc3ccc(-c4c(N)ncnc4N[C@@H](C)c4nn5ccc(C)c5c(=O)n4-c4ccccc4)cc32)cc1>>Cc1ccn2nc([C@H](C)Nc3ncnc(N)c3-c3ccc4ccn(S(=O)(=O)c5ccc(O)cc5)c4c3)n(-c3ccccc3)c(=O)c12,,CCOC(C)=O,ClCCl,BrB(Br)Br,,test
US20150166480A1,CC(C)(C)OC(=O)N1CCC(CN(Cc2ccccc2)c2ccc(Br)cc2)CC1.Cl>>Brc1ccc(N(Cc2ccccc2)CC2CCNCC2)cc1.Cl,,CCOC(C)=O,,C1COCCO1,,test
US20140378446A1,Nc1cccc(-n2c(=O)n(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)c1.O=C(Cl)/C=C/CBr>>Nc1ncnc2c1n(-c1ccc(Oc3ccccc3)cc1)c(=O)n2-c1cccc(NC(=O)/C=C/CBr)c1,,ClCCl,,,,test
US06127386,C=CCc1cc(OC[C@@H]2CCCN2C)cnc1Cl.Cl>>C=CCc1cc(OC[C@@H]2CCCN2C)cnc1Cl.Cl,,CCOCC,,CO,,test
US06559166B1,Fc1ccc(CCBr)c(F)c1.O=S(=O)(c1ccc(Br)cc1)C1CCNCC1>>O=S(=O)(c1ccc(Br)cc1)C1CCN(CCc2ccc(F)cc2F)CC1,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US20160168165A1,CC(C)(C)OC(=O)NCCOCCOCCN.CC(C)N1C(=O)S/C(=C\c2ccc(Sc3nc4ccccc4n3CC(=O)O)o2)C1=O>>CC(C)N1C(=O)S/C(=C\c2ccc(Sc3nc4ccccc4n3CC(=O)NCCOCCOCCNC(=O)OC(C)(C)C)o2)C1=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05202346,CC(=O)N1CCC(O)CC1.O=[N+]([O-])c1ccc(O)cc1>>CC(=O)N1CCC(Oc2ccc([N+](=O)[O-])cc2)CC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04337268,COCC(=O)Cl.Cc1cccc(C)c1N>>COCC(=O)Nc1c(C)cccc1C,,Cc1ccccc1,,CCN(CC)CC,,test
US20140350019A1,COC(=O)c1c(F)ccc(OS(=O)(=O)C(F)(F)F)c1F.OB(O)c1cccc(F)c1>>COC(=O)c1c(F)ccc(-c2cccc(F)c2)c1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CO,O=C([O-])[O-].[K+].[K+],,test
US20150210652A1,N#Cc1cccc(N)c1.O=C1OC(=O)c2ccccc21>>N#Cc1cccc(N2C(=O)c3ccccc3C2=O)c1,,C1COCCO1,,,,test
US20100239525A1,CC(C)(C)OC(=O)N1CCNCC1.CS(=O)(=O)OCCc1ccc(Nc2ncc3c(n2)-c2ccccc2C(c2ccccc2C(F)(F)F)C3)cc1>>CC(C)(C)OC(=O)N1CCN(CCc2ccc(Nc3ncc4c(n3)-c3ccccc3C(c3ccccc3C(F)(F)F)C4)cc2)CC1,,CCN(CC)CC,,,,test
US05093250,CCOC(=O)C1C(=O)C(C(=O)OCC)C2CC(=O)CC12.CO.COC(OC)OC>>CCOC(=O)C1C(=O)C(C(=O)OCC)C2CC(OC)(OC)CC12,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20140011800A1,C/C(N)=N/O.C[C@H]1CN(C(=O)OC(C)(C)C)C[C@H]1Nc1c(C(N)=O)cnn2cc(C(=O)O)cc12>>Cc1noc(-c2cc3c(N[C@@H]4CN(C(=O)OC(C)(C)C)C[C@@H]4C)c(C(N)=O)cnn3c2)n1,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US05001113,CC(C)[C@H](N)CO.O=C(Cl)CCl>>CC(C)C1COCC(=O)N1,,CCO,,,,test
US05821369,COC(=O)CC[C@@](C#N)(c1ccc(OC)c(OC)c1)C(C)C>>COC(=O)CCC(C#N)(c1ccc(OC)c(OC)c1)C(C)C,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20160096827A1,N#Cc1cc(-c2ncnc(Cl)n2)ccc1OC1CCOCC1.Nc1ccc(N2CCS(=O)(=O)CC2)cc1>>N#Cc1cc(-c2ncnc(Nc3ccc(N4CCS(=O)(=O)CC4)cc3)n2)ccc1OC1CCOCC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US05028606,CC(C)C(c1ccc(N)c(N)c1)n1ccnc1.CCCC(=O)C(=O)O>>CCCc1nc2cc(C(C(C)C)n3ccnc3)ccc2[nH]c1=O,,O,,CC(=O)O,[Na+].[OH-],test
US20040034220A1,CCCCC(Br)C(=O)OC.COC(=O)c1ccccc1O>>CCCCC(Oc1ccccc1C(=O)OC)C(=O)OC,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080255393A1,C1=CC=CCCCCCCC=C1>>C1=CCCCCCCCCCC1,,O,,,,test
US06218376B1,CCc1ccc2c(c1)C=Cc1oc(C)nc1C2c1c[nH]c(=O)[nH]c1=O.Clc1ccnc(Cl)n1>>CCc1ccc2c(c1)C=Cc1oc(C)nc1C2c1cn(-c2ccnc(Cl)n2)c(=O)[nH]c1=O,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060111351A1,CC(C)(C)OC(=O)n1cccc1-c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2C(=O)c2ccncc2)cc1>>O=C(c1ccncc1)c1cc(Cl)ccc1NS(=O)(=O)c1ccc(-c2ccc[nH]2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100009956A1,N#Cc1ncc(Br)c(N(N)C2CCCCC2)n1.O=C(Cl)c1ccc(-c2ccc(CCl)cc2)nc1>>N#Cc1ncc(Br)c(N(NC(=O)c2ccc(-c3ccc(CCl)cc3)nc2)C2CCCCC2)n1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20080146542A1,CN1CCN(c2ccc(C(=O)Nc3n[nH]c4sc(C(=O)NN)cc34)cc2)CC1.O=Cc1ccccc1>>CN1CCN(c2ccc(C(=O)Nc3n[nH]c4sc(C(=O)NN=Cc5ccccc5)cc34)cc2)CC1,Cl,C1CCOC1,,CCO,,test
US07482368B2,CCOC(=O)c1cc2cc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)ccc2n1C.Cn1c(C(=O)[O-])cc2cc(NC(=O)c3cc(C(F)(F)F)ccc3-c3ccccc3)ccc21.[K+]>>Cn1c(C(=O)[O-])cc2cc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)ccc21.[K+],,CC(C)O,O,[K+].[OH-],,test
US20130267546A1,CC(=O)CC(C)=O.N=C(N)N>>Cc1cc(C)nc(N)n1,,O,,O=S(=O)(O)O,O=C([O-])[O-].[Na+].[Na+],test
US06476021B1,O=c1c(Cc2cccnc2)cn2c3cc(Br)ccc3c(=O)c3cc(O)cc1c32.OCCCBr>>O=c1c(Cc2cccnc2)cn2c3cc(Br)ccc3c(=O)c3cc(OCCCO)cc1c32,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100286390A1,CC(O)c1ccncc1.O=C1NC(=O)c2ccccc21>>CC(c1ccncc1)N1C(=O)c2ccccc2C1=O,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150158864A1,C1CCOC1.F[C@H]1CNC[C@H](Nc2ncnc3[nH]ccc23)C1.O=C([O-])O>>C=CC(=O)N1C[C@H](F)C[C@@H](Nc2ncnc3[nH]ccc23)C1,,O=C([O-])O,[Na+],CO,ClCCl,test
US20110301175A1,CNOC.O=C(O)Cc1ccc(Nc2ncc(Br)cn2)cc1>>CON(C)C(=O)Cc1ccc(Nc2ncc(Br)cn2)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05073566,CCCCCCC(C(=O)OCC)n1cnc(NC(=O)c2cccc([N+](=O)[O-])c2C(=O)OCC)c1>>CCCCCCC(C(=O)OCC)n1cnc(NC(=O)c2cccc(N)c2C(=O)OCC)c1,[Pd],,,,,test
US20130040930A1,CCOC(=O)c1ccc(N)cc1.O=S(=O)(Cl)CCCCl>>O=C(O)c1ccc(N2CCCS2(=O)=O)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20160214956A1,CCOC(=O)c1cnn(-c2cccc(Cl)n2)c1C(F)(F)F.O=Cc1ccccc1B(O)O>>CCOC(=O)c1cnn(-c2cccc(-c3ccccc3C=O)n2)c1C(F)(F)F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20040068109A1,CCOC(=O)COc1cccc(NC(=O)c2ccc(OC)cc2)c1NC(=O)c1ccc(N2CCCN(C)CC2)cc1.Cl>>COc1ccc(C(=O)Nc2cccc(OCC(=O)O)c2NC(=O)c2ccc(N3CCCN(C)CC3)cc2)cc1.Cl,,CO,,Cl,[Na+].[OH-],test
US20110098431A1,CC(Br)c1ccccc1.Nc1cccc2cccnc12>>CC(Nc1cccc2cccnc12)c1ccccc1,,CCN(CC)CC,,,,test
US20140051679A1,C1CNC1.O=CC(=O)O.OB(O)c1ccsc1>>O=C(O)C(c1ccsc1)N1CCC1,,ClCCl,,O,,test
US06323202B1,CCCCN(C)C(=O)c1cccc(NC(=O)c2ccc(Cl)cc2OC)c1>>CCCCN(C)C(=O)c1cccc(NC(=O)c2ccc(Cl)cc2O)c1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20160113928A1,CNC1CCN(c2nnc(-c3ccnn3C)c3ccncc23)CC1.O=C=Nc1ccc(F)cc1C(F)(F)F>>CN(C(=O)Nc1ccc(F)cc1C(F)(F)F)C1CCN(c2nnc(-c3ccnn3C)c3ccncc23)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080269195A1,COc1cccc2c1CC(=O)CC2.NO>>COc1cccc2c1CC(=NO)CC2,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20080167303A1,CC(C)(C)OC(=O)N1CCOC(CN2c3ccccc3N(c3ccccc3)S2(=O)=O)C1.Cl>>Cl.O=S1(=O)N(CC2CNCCO2)c2ccccc2N1c1ccccc1,,CO,,,,test
US20130303524A1,CC(C)(C)[Si](C)(C)Cl.OC(CNCc1ccco1)Cn1c2ccccc2c2ccccc21>>CC(C)(C)[Si](C)(C)OC(CNCc1ccco1)Cn1c2ccccc2c2ccccc21,,ClCCl,,c1c[nH]cn1,,test
US06403610B1,COC(=O)C[C@H]1CNCC[C@H]1CCC(=O)c1ccnc2ccc(OC)cc12.ClCCSC1CCCC1>>COC(=O)C[C@H]1CN(CCSC2CCCC2)CC[C@H]1CCC(=O)c1ccnc2ccc(OC)cc12,,CC#N,O,[I-].[K+],,test
US20090264434A1,CC(=O)Cn1nc([N+](=O)[O-])cc1C>>Cc1cc([N+](=O)[O-])nn1CC(C)O,,CCO,,[BH4-].[Na+],,test
US20130085132A1,C=C(CC(=O)O)C(=O)O.COc1ccc(CN)c(OC)c1>>COc1ccc(CN2CC(C(=O)O)CC2=O)c(OC)c1,,Cc1ccccc1,,,,test
US03944567,NC1CCCc2sccc21.O=C(Cl)Cl>>O=C=NC1CCCc2sccc21,,Cc1ccccc1,,Cl,,test
US20120208814A1,CC(=O)N1c2ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)cc2[C@H](N(C(=O)[O-])C(C)(C)C)C[C@@H]1C.Cl>>CC(=O)N1c2ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)cc2[C@H](N)C[C@@H]1C.Cl,,C1COCCO1,,,,test
US20150119394A1,CCOC(=O)c1c(S(=O)(=O)N2CCO[C@H](COc3ccc(-c4cccnc4)cc3)C2)c2cc(Cl)ccc2n1S(=O)(=O)c1ccccc1.N>>NC(=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)N1CCO[C@H](COc2ccc(-c3cccnc3)cc2)C1,,CC(C)O,,,,test
US20140256734A1,CC(C)(C)OC(=O)N1CC[C@H](Nc2nc(C#N)cc3ccccc23)C1.CCOC(=O)NN>>CC(C)(C)OC(=O)N1CC[C@H](Nc2nc(-c3n[nH]c(=O)[nH]3)cc3ccccc23)C1,,CCOC(C)=O,,CN1CCCC1=O,,test
US20120065195A1,CC1(C)CCc2cnc(-c3cccc(Cl)c3)cc2C12NC(=O)NC2=O.CI>>CN1C(=O)NC2(C1=O)c1cc(-c3cccc(Cl)c3)ncc1CCC2(C)C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20020049243A1,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)N1CCCCC1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)O[C@@H]2C[C@@H](C(=O)N3CCCCC3)N(C(=O)OC(C)(C)C)C2)cc1,CN(C)c1ccncc1,ClCCl,,,,test
US20020132810A1,CC(C)(F)CCC(CC(O)C(Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C(=N)N.CS(=O)(=O)Cl>>CC(C)(F)CCC(CC(O)C(Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C(N)=NS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20040138286A1,c1cc2[nH]ncc2cc1OC1CCC(OC2CCCCO2)CC1>>OC1CCC(Oc2ccc3[nH]ncc3c2)CC1,,CO,,,,test
US20050182059A1,CCCOc1ccc(N)nn1.COc1ccc2c(c1)CCC(Br)C2=O>>CCCOc1ccc2nc3c(n2n1)CCc1cc(OC)ccc1-3,,CCO,,O=C([O-])O.[Na+],,test
US20040214841A1,CC(C)(C)OC(=O)N1CCC(COc2cc(OC3CCOCC3)c3c(Nc4c(Cl)ccc5c4OCO5)ncnc3c2)CC1>>Clc1ccc2c(c1Nc1ncnc3cc(OCC4CCNCC4)cc(OC4CCOCC4)c13)OCO2,,ClCCl,,O=C(O)C(F)(F)F,,test
US05593983,CC([O-])=S.CC1(C)CN([C@H]2C[C@@]3(C)[C@@H](CC[C@H]4[C@@H]5CC[C@H](C(=O)CCl)[C@@]5(C)CC(=O)[C@@H]43)C[C@@H]2O)CCO1>>CC(=O)SCC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@@H](N5CCOC(C)(C)C5)C[C@]4(C)[C@H]3C(=O)C[C@]12C,,CCO,,O,,test
US20110034451A1,Cc1c(Cl)nnc(NN)c1C.N#CBr>>Br.Cc1c(Cl)nn2c(N)nnc2c1C,,CCO,O,,,test
US20110105474A1,CCOC(=O)/C=C/c1cccc(/C=C/C(=O)NOC2CCCCO2)c1>>O=C(O)/C=C/c1cccc(/C=C/C(=O)NOC2CCCCO2)c1,,C1CCOC1,,[Li+].[OH-],,test
US20100197715A1,CN1CC(c2ccccc2)([N+](=O)[O-])CC(F)C1=O>>CN1CC(N)(c2ccccc2)CC(F)C1=O,[Ni],C1CCOC1,,,,test
US20090286974A1,Brc1cnc(Br)s1.OCCC1(N2CCCC2)CCNCC1>>OCCC1(N2CCCC2)CCN(c2ncc(Br)s2)CC1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20090170921A1,COCCn1c(-c2ccc(C(C)C)cc2)nc2cc(Br)cc(OC)c21.O=S(=O)(c1ccccc1)N(F)S(=O)(=O)c1ccccc1>>COCCn1c(-c2ccc(C(C)C)cc2)nc2cc(F)cc(OC)c21,,C1CCOC1,,[Li]CCCC,,test
US05889013,CCc1c(S(C)=O)n(CCCCOC(C)=O)c(=S)[nH]c1=O.[SeH]c1ccccc1>>CCc1c([Se]c2ccccc2)n(CCCCO)c(=S)[nH]c1=O,,CCO,,Cl,[Na+].[OH-],test
US20110070317A1,CC(C)(C)OC(=O)N[C@@H]1CCCNC1.O=C(Nc1c[nH]c2ncc(Br)c(F)c12)[C@@H]1CCCO1>>CC(C)(C)OC(=O)N[C@@H]1CCCN(c2c(Br)cnc3[nH]cc(NC(=O)[C@@H]4CCCO4)c23)C1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20090042929A1,NC12CC3CC(CC(C3)C1)C2.O=S(=O)(Cl)Cc1ccc(Cl)cc1>>O=S(=O)(Cc1ccc(Cl)cc1)NC12CC3CC(CC(C3)C1)C2,,ClCCl,,c1ccncc1,,test
US20070265265A1,CC(C)(C)OC(=O)N1CC(N)C1.O=C(O)c1ccccc1-c1csc(NC(=O)C2CCCN2C(=O)OCc2ccccc2)n1>>CC(C)(C)OC(=O)N1CC(NC(=O)c2ccc(-c3csc(NC(=O)C4CCCN4C(=O)OCc4ccccc4)n3)cc2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110034433A1,CC1=C(C#N)[C@@H](c2ccc(C#N)cc2S(C)(=O)=O)N(C(=O)Oc2ccc([N+](=O)[O-])cc2)C(=O)N1c1cccc(C(F)(F)F)c1.OCCN1CCNCC1>>CC1=C(C#N)[C@@H](c2ccc(C#N)cc2S(C)(=O)=O)N(C(=O)N2CCN(CCO)CC2)C(=O)N1c1cccc(C(F)(F)F)c1,,CC#N,,,,test
US20160052898A1,O=C(CN1CCOCC1)Nc1cc(C(=O)Nc2ccc(-c3ccccc3)cc2)ccc1OCc1ccccc1>>O=C(CN1CCOCC1)Nc1cc(C(=O)Nc2ccc(-c3ccccc3)cc2)ccc1O,[Pd],C1CCOC1,,,,test
US20030158413A1,COC(=O)c1ccc2c(c1)CCCC2NC(=O)OCc1ccccc1>>O=C(NC1CCCc2cc(C(=O)O)ccc21)OCc1ccccc1,,[Na+],[OH-],,,test
US20100331293A1,Cc1c(N2CCCC2=O)nc2cc(F)cc(F)c2c1Br.Nc1cncc(N2CCOCC2)c1>>Cc1c(N2CCCC2=O)nc2cc(F)cc(F)c2c1Nc1cncc(N2CCOCC2)c1,,Cc1ccccc1,,,,test
US20130231477A1,Cc1ccc(-c2ncccc2Cl)cc1.O=[Se]=O>>O=Cc1ccc(-c2ncccc2Cl)cc1,,C1COCCO1,,,,test
US20100029707A1,O=C(O)CC(=O)O.O=Cc1ccco1>>O=C(O)/C=C/c1ccco1,,O,c1ccncc1,C1CCNCC1,Cl,test
US20040044008A1,N#Cc1cccc(CN2CCN(c3ccc(NC(=O)c4ccccc4-c4ccc(C(F)(F)F)cc4)cc3)CC2)c1.O=C(O)CC(O)(CC(=O)O)C(=O)O>>N#Cc1cccc(CN2CCN(c3ccc(NC(=O)c4ccccc4-c4ccc(C(F)(F)F)cc4)cc3)CC2)c1.O=C(O)CC(O)(CC(=O)O)C(=O)O,,CO,,,,test
US20060019943A1,CC1C2(CCCC1(C=O)c1ccccc1)OCCO2>>OCC1(c2ccccc2)CCCC2(C1)OCCO2,,CO,,[BH4-].[Na+],,test
US20050239826A1,C1=CCNC1.ClCc1ccccc1>>C1=CCN(Cc2ccccc2)C1,,CC#N,,COC(C)(C)C,,test
US20090186879A1,CI.OC(c1cccc2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl)C(F)(F)F>>COC(c1cccc2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl)C(F)(F)F,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US06251917B1,BrCc1ccc2ccccc2c1.COC(=O)c1ccccc1O>>COC(=O)c1ccc(OCc2ccc3ccccc3c2)cc1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20090221547A1,BrCc1ccc(Br)cc1.Oc1ccc(-c2ccccc2F)c(C(F)(F)F)c1>>Fc1ccccc1-c1ccc(OCc2ccc(Br)cc2)cc1C(F)(F)F,,CN(C)C=O,,[H-].[Na+],,test
US20050054626A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](NC(=O)OCc2ccccc2)[C@H](CO)C1.Oc1ccccc1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@H](NC(=O)OCc2ccccc2)[C@H](COc2ccccc2)C1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130231331A1,COC(=O)CC(C(C)=O)C(=O)OC.NC1N=NC(c2cccc(-c3ccccc3)c2)=N1>>COC(=O)Cc1c(C)nc2nc(-c3cccc(-c4ccccc4)c3)nn2c1O,,Cc1ccccc1C,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05047550,CCOS(=O)(=O)OCC.COC(=O)c1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(O)c1SC(F)(F)F>>CCOc1c(SC(F)(F)F)c(C(=O)OC)nn1-c1c(Cl)cc(C(F)(F)F)cc1Cl,,C1COCCO1,,[H-].[Na+],,test
US20050148627A1,CCOC(=O)/C=C/C(F)(F)F.COc1ccc(C=O)c(O)c1C>>CCOC(=O)C1=Cc2ccc(OC)c(C)c2OC1C(F)(F)F,,CN(C)C=O,CO,O=C([O-])[O-].[K+].[K+],,test
US20110230495A1,COC(=O)c1cccnc1C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(c2ncccc2CO)CC1,,C1CCOC1,CCOC(C)=O,CO,[BH4-].[Na+],test
US20110172245A1,COC(=O)c1cccc(Oc2ccc3nc(N)oc3c2)c1.O=C(Cl)C1CC1>>COC(=O)c1cccc(Oc2ccc3nc(NC(=O)C4CC4)oc3c2)c1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20040102479A1,CC1(c2ccc(F)cc2)CSc2cc(O)ccc2C1CCCCCCCCCSCCCC(F)(F)C(F)(F)F.O>>CC1(c2ccc(F)cc2)CSc2cc(O)ccc2C1CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F,,C1CCOC1,,CCCCCC,CCOC(C)=O,test
US20150080549A1,CC(C)(O)C(=O)O.O=C(O)[C@@H]1CCCN1C(=O)OCC1c2ccccc2-c2ccccc21>>CC(C)(OC(=O)[C@@H]1CCCN1C(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20120101115A1,CI.O=Cc1ccccc1C(=O)O>>O=Cc1ccccc1CC(=O)O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05556864,CN(C)CCCCl.COc1ccccc1CCCCc1ccccc1O>>COc1ccccc1CCCCc1ccccc1OCCCN(C)C,,CC(=O)N(C)C,,Cl,[H-].[Na+],test
US20100029657A1,NC(=O)CCC(=O)NI.O=C(N1C2CCC1CC(c1ccnc3cc(-c4ccncc4)nn13)C2)C(F)(F)F>>O=C(N1C2CCC1CC(c1ccnc3c(I)c(-c4ccncc4)nn13)C2)C(F)(F)F,,ClCCl,,,,test
US20030171431A1,CCI.O=C1CCC2C1C2(F)C(=O)O>>CCOC(=O)C1(F)C2CCC(=O)C21,,CN(C)C=O,,Cl,O=C([O-])O.[Na+],test
US20070066624A1,CC(C)(C)OC(=O)CBr.Cc1nc(Sc2ccc(O)cc2)ccc1CN1CCC(N2C(=O)OC[C@H]2c2cccc(Cl)c2)CC1>>Cc1nc(Sc2ccc(OCC(=O)OC(C)(C)C)cc2)ccc1CN1CCC(N2C(=O)OC[C@H]2c2cccc(Cl)c2)CC1,,C1CCOC1,,[H-].[Na+],,test
US20110105474A1,CCOC(=O)/C=C/c1cccc(/C=C/C(=O)O)c1.NOC1CCCCO1>>CCOC(=O)/C=C/c1cccc(/C=C/C(=O)NOC2CCCCO2)c1,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20030082510A1,CC(=O)CCl.Cc1c(CN2C(=O)c3ccccc3C2=O)c(=O)oc2c(C)c(O)ccc12>>CC(=O)COc1ccc2c(C)c(CN3C(=O)c4ccccc4C3=O)c(=O)oc2c1C,,ClCCl,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US04242355,CCCN(CCc1cccc(OC)c1)CCc1c[nH]c2ccccc12.Cl>>CCCN(CCc1cccc(O)c1)CCc1c[nH]c2ccccc12.Cl,,O,,[NH4+].[OH-],,test
US06096898,O=C(O)c1sc(Cl)c(Cl)c1Cl.O=S(Cl)Cl>>O=C(Cl)c1sc(Cl)c(Cl)c1Cl,,ClCCCl,,CN(C)C=O,,test
US20090306052A1,CNC(=O)c1ccc(Cl)nc1.Oc1ccc2c(c1)CCC2N1CCCC1>>CNC(=O)c1ccc(Oc2ccc3c(c2)CC(N2CCCC2)C3)nc1,,CN(C)C=O,,[H-].[Na+],,test
US20130109653A1,COc1ccc(COC2CC(C)(C)Cc3nc(C4CCN(c5ncc(OC6CCN(C)CC6)cn5)CC4)c(C(F)c4ccc(C(F)(F)F)cc4)c(C4CCC(F)(F)CC4)c32)cc1>>CN1CCC(Oc2cnc(N3CCC(c4nc5c(c(C6CCC(F)(F)CC6)c4C(F)c4ccc(C(F)(F)F)cc4)C(O)CC(C)(C)C5)CC3)nc2)CC1,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US04381303,CCCCN1C(=O)c2c(c(C)nn2C)Nc2ncccc21.CI>>CCCCN1C(=O)c2c(c(C)nn2C)N(C)c2ncccc21,,CN(C)C=O,,[H-].[Na+],,test
US20050277670A1,COC(=O)COc1ccc(N(Cc2ccsc2)C2CCN([C@H](C)CCNC(=O)c3c(C)ncnc3C)CC2)cc1.N>>Cc1ncnc(C)c1C(=O)NCC[C@@H](C)N1CCC(N(Cc2ccsc2)c2ccc(OCC(N)=O)cc2)CC1,,CO,,,,test
US20100075948A1,N#CCc1ccc(F)cc1.O=Cc1cccc(Cl)c1F>>N#C/C(=C\c1cccc(Cl)c1F)c1ccc(F)cc1,,CO,,C[O-].[Na+],,test
US20040157866A1,C=C(C)c1ccc(-c2ccccc2C(=O)Nc2ccc3c(c2)CCN3C(=O)Cc2ccccn2)cc1.CO>>CC(C)(O)c1ccc(-c2ccccc2C(=O)Nc2ccc3c(c2)CCN3C(=O)Cc2ccccn2)cc1,,ClC(Cl)Cl,,Cl,,test
US20050234065A1,CC(C)(C)OC(=O)N[C@H](C(=O)N1CCCC1)[C@@H]1CC[C@H](O)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N[C@H](C(=O)N1CCCC1)[C@H]1CC[C@@H](OS(C)(=O)=O)CC1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US05157041,CC(C)(C)OC(=O)[C@@H]1CCCN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(N)=O.O=C(Cl)c1ccc2ccccc2c1>>CC(C)(C)OC(=O)[C@@H]1CCCN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150011527A1,C[C@@H](NC(=O)[C@H](Cc1ccc(-c2ncc(Br)cn2)cc1)NC(=O)c1ccc(C(C)(C)C)s1)C(=O)OC(C)(C)C.OB(O)c1ccc(O)cc1>>C[C@@H](NC(=O)[C@H](Cc1ccc(-c2ncc(-c3ccc(O)cc3)cn2)cc1)NC(=O)c1ccc(C(C)(C)C)s1)C(=O)OC(C)(C)C,,CC#N,O,C1CCOC1,O=C([O-])[O-].[Na+].[Na+],test
US20150011546A1,CC(=O)C1CN(C(=O)OC(C)(C)C)CCO1>>CC(=O)C1CNCCO1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100279872A1,COB(OC)OC.Cc1cc(C)cc(-c2ccccc2)c1.[Li]C(C)(C)C>>CCCC(C)C.Cc1cc(-c2ccccc2)cc(C)c1B(O)O,,C1CCOC1,,Cl,,test
US20120214784A1,Cc1nn(-c2ccccc2F)cc1C(=O)OC(C)(C)C.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)c1cn(-c2ccccc2F)nc1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20080261946A1,N#CCOc1ccc(Cl)cc1C#N>>N#Cc1oc2ccc(Cl)cc2c1N,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05089519,C#CC(=O)OCc1ccccc1.Oc1cccc2c1OCO2>>O=C1CCOc2c1ccc1c2OCO1,,C1CCOC1,,CN1CCOCC1,,test
US04278672,CCN(CC)C(=O)NC.O=C=Nc1ccccc1>>CCN(CC)C(=O)N(C)C(=O)Nc1ccccc1,,ClCCl,,,,test
US20120208819A1,Nc1ncnc2ccc(-c3ccc(CNc4ncc(Br)cc4S(=O)(=O)NCc4ccc(F)c(F)c4)s3)cc12>>Nc1ncnc2ccc(-c3ccc(CNc4ncccc4S(=O)(=O)NCc4ccc(F)c(F)c4)s3)cc12,[Pd],CO,,[H][H],,test
US20030153562A1,Cc1cc(C(=O)CO)no1.Nc1n[nH]c(=O)c2ccccc12>>Cc1cc(-c2cnc3c4ccccc4c(=O)[nH]n23)no1,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US20130023545A1,Cc1cc(-c2nc3cnc(Cl)nc3o2)cc(C)c1O.Oc1ccccc1F>>Cc1cc(-c2nc3cnc(Oc4ccccc4F)nc3o2)cc(C)c1O,,CC(=O)N(C)C,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20120258948A1,CCOC(=O)[C@@](C)(CCn1ccc(I)c(F)c1=O)S(C)(=O)=O.OB(O)c1ccccc1>>CCOC(=O)[C@@](C)(CCn1ccc(-c2ccccc2)c(F)c1=O)S(C)(=O)=O,[Pd],C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US20050239766A1,CC(C)(C)OC(=O)COc1ccc(C2C(CCOc3ccc(F)cc3)C(=O)N2c2ccc(F)cc2)cc1>>O=C(O)COc1ccc(C2C(CCOc3ccc(F)cc3)C(=O)N2c2ccc(F)cc2)cc1,,O=CO,,,,test
US04555572,COc1ccc(Nc2c([N+](=O)[O-])ccc(Cl)c2C(=O)O)cc1>>COc1ccc2[nH]c3c([N+](=O)[O-])ccc(Cl)c3c(=O)c2c1,,Clc1ccccc1,,O=P(Cl)(Cl)Cl,,test
US20130197009A1,CCO.C[C@@H]1CN(c2ccc(C#N)c(F)c2)[C@@H](C)CN1>>CCOc1cc(N2C[C@@H](C)NC[C@@H]2C)ccc1C#N,,CCOC(C)=O,O,C1CCOC1,CC(C)(C)[O-].[K+],test
US05236924,N#CCBr.Oc1ccc(Cc2ccccc2)cc1>>N#CCOc1ccc(Cc2ccccc2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20140274933A1,COc1ccc(C(=O)c2cccc(F)c2)c(C(=O)O)c1.NN>>COc1ccc2c(-c3cccc(F)c3)n[nH]c(=O)c2c1,,CCO,,O,,test
US20030073699A1,CCN(CC)CC.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.c1ccc(CC2CCNCC2)cc1>>NC(=O)Oc1ccc([N+](=O)[O-])cc1N1CCC(Cc2ccccc2)CC1,,ClCCl,,O,,test
US20130005707A1,CNCc1ccc(OC)cc1.O=[N+]([O-])c1ccnc(Cl)c1>>COc1ccc(CN(C)c2cc([N+](=O)[O-])ccn2)cc1,,COCCOC,,,,test
US05030646,COc1ccc2c(c1)CC(=O)N2C.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>COc1ccc2c(c1)CC(=S)N2C,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20140221361A1,C=C(CNCCN(C)C)[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC(C)(C)C)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(CNCCN(C)C)[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150291598A1,Nc1cnc(Br)cn1.O=CCCl>>Brc1cn2ccnc2cn1,,CO,,,,test
US04888044,COC(=O)CBr.Cc1c(C(F)(F)F)noc1O>>COC(=O)COc1onc(C(F)(F)F)c1C,,O,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120149684A1,CC(C)(C)OC(=O)N1CCC(c2nc(C3CCOCC3)cn2CCOC2CCCCO2)CC1>>CC(C)(C)OC(=O)N1CCC(c2nc(C3CCOCC3)cn2CCO)CC1,,CCOC(C)=O,,C1CCOC1,Cl,test
US20100261702A1,CCc1cc(C(=O)O)cc(C)c1OCc1ccccc1.CN(C)C(OC(C)(C)C)OC(C)(C)C>>CCc1cc(C(=O)OC(C)(C)C)cc(C)c1OCc1ccccc1,,CCOC(C)=O,Cc1ccccc1,,,test
US05445763,C1CCOC1.CCCCCCCCOc1cnc(-c2ccc(O)cc2)c(F)c1.CCOC(=O)N=NC(=O)OCC.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CCCCCCCCOc1cnc(-c2ccc(OC[C@@H]3O[C@H]3CCCCC)cc2)c(F)c1,,C1CCOC1,,,,test
US20100160324A1,Nc1c[nH]nc1-c1cccnc1.O=C(O)c1c(F)cccc1F>>O=C(Nc1c[nH]nc1-c1cccnc1)c1c(F)cccc1F,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20070092816A1,O=C(O)c1ccc(C2C3C=CC(N3)C(c3ccc(C(=O)O)cc3)C3CCC(N3)C(c3ccc(C(=O)O)cc3)C3C=CC(N3)C(c3ccc(C(=O)O)cc3)C3CCC2N3)cc1.[O-2].[O-2].[Ti+4]>>C1=Cc2cc3ccc(cc4nc(cc5ccc(cc1n2)[nH]5)C=C4)[nH]3.[O-2].[O-2].[Ti+4],,CCCCO,,Cc1ccccc1C,,test
US06329370B1,C#Cc1ccccc1.COc1ccc2c(=O)[nH]ncc2c1OS(=O)(=O)C(F)(F)F>>COc1ccc2c(=O)[nH]ncc2c1C#Cc1ccccc1,,CN(C)C=O,,CCN(CC)CC,O,test
US04079181,C1COCCN1.CC(OS(C)(=O)=O)=C(C(=O)OCc1ccc([N+](=O)[O-])cc1)N1C(=O)C(NC(=O)COc2ccccc2)C1SC(=O)OCC1CC1>>CC(=C(C(=O)OCc1ccc([N+](=O)[O-])cc1)N1C(=O)C(NC(=O)COc2ccccc2)C1SC(=O)OCC1CC1)N1CCOCC1,,c1ccccc1,,,,test
US20100256156A1,CCc1sc(C2CCSCC2)cc1C(O)C1CCCCC1.O=S(Cl)Cl>>CCc1sc(C2CCSCC2)cc1C(Cl)C1CCCCC1,,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US20140128372A1,CC(C)(C)OC(=O)NCC(O)c1ccc(Cl)cc1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)NCC(c1ccc(Cl)cc1)N1C(=O)c2ccccc2C1=O,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140274701A1,CC(C)OB1OC(C)(C)C(C)(C)O1.FC1(F)Oc2ccc(Br)c(Cl)c2O1>>CC1(C)OB(c2ccc3c(c2Cl)OC(F)(F)O3)OC1(C)C,,C1CCOC1,,,,test
US20100179126A1,Cc1ncc(C2=CCN(C(=O)OC(C)(C)C)CC2(C)C)cc1[N+](=O)[O-]>>Cc1ncc(C2=CCNCC2(C)C)cc1[N+](=O)[O-],,CO,,Cl,,test
US20030045575A1,BrCc1ccccc1.Nc1ccc(O)c(C(=O)O)c1>>O=C(O)c1cc(NCc2ccccc2)ccc1O,,CN(C)C=O,,CCN(CC)CC,,test
US04782076,CC(C)[Si](OS(=O)(=O)C(F)(F)F)(C(C)C)C(C)C.[Li]C#CC>>CC#C[Si](C(C)C)(C(C)C)C(C)C,,CCOCC,,,,test
US20110269756A1,CCCN1CCN(C)CC1.Nc1cccc(Cn2c(=O)sc3ccc(Cl)cc32)c1.O=C(O)Cl>>CN1CCN(CCCOC(=O)Nc2cccc(Cn3c(=O)sc4ccc(Cl)cc43)c2)CC1,,C1CCOC1,,CCN(C(C)C)C(C)C,ClCCl,test
US20120010190A1,COc1ccc(C(=O)CC(c2ccc(Br)cc2)c2ccc(Cl)cc2F)cn1>>O=C(CC(c1ccc(Br)cc1)c1ccc(Cl)cc1F)c1ccc(=O)[nH]c1,,C1COCCO1,,Cl,,test
US20080181866A1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.CN(C)C=O.Nc1nc(-c2ccc(C(=O)NC3CC3)cc2)cs1.O=C(NC(CO)C(=O)O)OCc1ccccc1>>O=C(NC1CC1)c1ccc(-c2csc(NC(=O)C3CO[C@@H](c4ccccc4)N3C(=O)OCc3ccccc3)n2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20120165304A1,CC(C)(C)OC(=O)NC1CCNCC1.CC(C)=CCBr>>CC(C)=CCN1CCC(NC(=O)OC(C)(C)C)CC1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20150025075A1,CON.O=C1CCc2cc(Cl)cc(Cl)c21>>CON=C1CCc2cc(Cl)cc(Cl)c21,,CO,O,Cl,,test
US20140135319A1,C=CCN.CS(=O)(=O)c1nc(-c2ccccc2)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12>>C=CCNc1nc(-c2ccccc2)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12,,CN(C)C=O,,,,test
US20110172193A1,COc1c(N2CCCC(=C(F)CNC(=O)[C@H](C)NC(=O)OC(C)(C)C)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12.Cl>>COc1c(N2CCCC(=C(F)CNC(=O)[C@H](C)N)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12.Cl,,ClCCl,,C1COCCO1,,test
US20140135369A1,COC(=O)C1(C)CCCC2(CN(CC(C)(C)C)C(=O)O2)C1>>CC(C)(C)CN1CC2(CCCC(C)(CO)C2)OC1=O,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080167361A1,C=O.COc1ccc(S(=O)(=O)c2ccc(C3CCNC3)c(C)c2)cc1>>COc1ccc(S(=O)(=O)c2ccc(C3CCN(C)C3)c(C)c2)cc1,,CO,,[BH4-].[Na+],,test
US20080242677A1,Cc1ccc(C)c(N2CCN(C(=O)C3CN3S(=O)(=O)c3ccccc3)CC2)c1.O=C=Nc1ccccc1>>Cc1ccc(C)c(N2CCN(C(=O)C3CN(S(=O)(=O)c4ccccc4)C(=O)N3c3ccccc3)CC2)c1,,C1CCOC1,CCOC(C)=O,[I-].[Na+],,test
US20040162276A1,C[Si](C)(C)CCOCCl.O=C(c1n[nH]c2c1C=CC(c1ccccc1)(c1ccccc1)C2)C1CC1>>C[Si](C)(C)CCOCn1nc(C(=O)C2CC2)c2c1CC(c1ccccc1)(c1ccccc1)C=C2,,CN(C)C=O,,O,[H-].[Na+],test
US20140213616A1,COc1cc(F)ccc1O.N#Cc1ccc(C(=O)Nc2cc[nH]c(=O)c2)c(F)c1>>COc1cc(F)ccc1Oc1cc(C#N)ccc1C(=O)Nc1cc[nH]c(=O)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04405642,COc1ccc(CCNCC(O)C(=O)O)cc1OC.COc1ccccc1CO>>COc1ccccc1COC(=O)C(O)CNCCc1ccc(OC)c(OC)c1,,c1ccccc1,,Cl,,test
US20060287286A1,CS(=O)(=O)Cl.OCCCCc1cccc(I)c1>>CS(=O)(=O)OCCCCc1cccc(I)c1,,ClCCl,,CC(C)NC(C)C,,test
US04431828,CC1C(CN)CC2CC1C2(C)C>>CC1C(CN)CC2CC1C2(C)C,,CCOC(C)=O,,Cl,[Na+].[OH-],test
US20050020659A1,COC(=O)c1cc(N)n(C(=O)OC(C)(C)C)n1.Cc1cccc(SCc2ccccc2C(=O)Cl)c1>>COC(=O)c1cc(NC(=O)c2ccccc2CSc2cccc(C)c2)[nH]n1,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20120190665A1,CC(C)=CCBr.COc1ccc(Cl)cc1-c1[nH]ncc1NC(=O)c1cnn2cccnc12>>COc1ccc(Cl)cc1-c1nn(CC=C(C)C)cc1NC(=O)c1cnn2cccnc12,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20090325900A1,COc1ccccc1C(=O)C(C)(C)c1ccc(F)c(NC(=O)OC(C)(C)C)c1>>COc1ccccc1C(O)C(C)(C)c1ccc(F)c(NC(=O)OC(C)(C)C)c1,,C1CCOC1,O,[BH4-].[Na+],,test
US20140378446A1,CC(C)(C)OC(=O)N1CCC[C@@H](n2c(=O)n(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1>>Nc1ncnc2c1n(-c1ccc(Oc3ccccc3)cc1)c(=O)n2[C@@H]1CCCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090131597A1,C1CCCCC1.C=CC=C.C=Cc1ccccc1.Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1>>C=CC=C.C=Cc1ccccc1.C=Cc1ccccc1,,C1CCCCC1,C1CCOC1,[Li]CCCC,,test
US06610694B1,CS(=O)(=O)OCCCCCCNc1ccc2nncn2n1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>c1ccc(C(c2ccccc2)N2CCN(CCCCCCNc3ccc4nncn4n3)CC2)cc1,,CN(C)C=O,,[I-].[K+],,test
US20140315902A1,COc1cc(OC)c(F)c(N2Cc3cnc(N)c(/C=C/c4ccccc4)c3N(C)C2=O)c1F>>COc1cc(OC)c(F)c(N2Cc3cnc(N)c(CCc4ccccc4)c3N(C)C2=O)c1F,[Pd],CO,,,,test
US20150045368A1,CC1(C)OC(=O)N[C@H]1c1ccccc1.Fc1ccc(I)cn1>>CC1(C)OC(=O)N(c2ccc(F)nc2)[C@H]1c1ccccc1,[Cu]I,C1COCCO1,O,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US04792563,Cc1ccc(S(=O)(=O)Cl)cc1.OCc1cccc(Oc2ccccc2)n1>>ClCc1cccc(Oc2ccccc2)n1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CCOCC,test
US20130345412A1,C=CCCC(=O)OC(=O)CCC=C.CC(C)(C)OC(=O)CN(CC(=O)OC(C)(C)C)[C@@H](CO)C(=O)OC(C)(C)C>>C=CCCC(=O)OC[C@@H](C(=O)OC(C)(C)C)N(CC(=O)OC(C)(C)C)CC(=O)OC(C)(C)C,,CC#N,,CCN(C(C)C)C(C)C,,test
US20160251339A1,COc1ccc(S(=O)(=O)n2cc(C(F)F)c3cc(F)c(F)cc32)cc1N1CCN(C(=O)C(Cl)(Cl)Cl)CC1>>COc1ccc(S(=O)(=O)n2cc(C(F)F)c3cc(F)c(F)cc32)cc1N1CCNCC1,,C1CCOC1,,[K+].[OH-],,test
US06172005B2,CSc1nc(Cl)ncc1C.FC(F)(F)c1cc[nH]n1>>CSc1nc(-n2ccc(C(F)(F)F)n2)ncc1C,,CCCCCC,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US05258382,CCOC(=O)C(C(=O)OCC)n1cccc1.O=C(Cl)C(Cl)(Cl)Cl>>CCOC(=O)C(C(=O)OCC)n1cccc1C(=O)C(Cl)(Cl)Cl,,ClC(Cl)Cl,,,,test
US05021420,O=S1(=O)c2cccc3cccc(c23)N1CCCCl.c1ccc2c(N3CCNCC3)noc2c1>>O=S1(=O)c2cccc3cccc(c23)N1CCCN1CCN(c2noc3ccccc23)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US20140194415A1,Fc1cc(Br)ccc1CBr.O.[C-]#N>>NC(=O)Cc1ccc(Br)cc1F,,O,,CCO,,test
US20050026916A1,CC(=O)OC(C)=O.Fc1ccc(CSC2=N[C@@H](c3ccccc3)[C@@H](c3ccccc3)N2)cc1>>CC(=O)N1C(SCc2ccc(F)cc2)=N[C@@H](c2ccccc2)[C@H]1c1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,Cl,test
US20160137696A1,CCCCCCCCCCC(=O)Cl.NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O>>CCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O,,CO,ClCCl,CCN(C(C)C)C(C)C,,test
US04602016,NS(=O)(=O)c1ccccc1.O=C(O)c1ccc(OCCn2ccnc2)cc1>>O=S(=O)(N=C(O)c1ccc(OCCn2ccnc2)cc1)c1ccccc1,,CN(C)C=O,O,,,test
US04071625,C[C@@H]1C=C2CC(=O)CC[C@]2(C=O)[C@H]2CC[C@]3(C)C(=O)CC[C@H]3[C@@H]21>>C[C@@H]1C[C@H]2CC(=O)CC[C@]2(C=O)[C@H]2CC[C@]3(C)C(=O)CC[C@H]3[C@@H]21,[Pd],CCO,,,,test
US20060100425A1,Cc1noc(C)c1CN1C(=O)c2ccccc2C1=O>>Cc1noc(C)c1CN1C(=O)c2ccccc2C1O,,CO,,[BH4-].[Na+],,test
US03947434,Cc1cc(Nc2ccccc2)c2c(ccc3nc[nH]c32)n1.Cl.Nc1ccc(I)cc1>>Cc1cc(Nc2ccc(I)cc2)c2c(ccc3nc[nH]c32)n1.Cl,,CCO,,,,test
US20090181942A1,CCOC(=O)C[C@H]1O[C@H](c2cccnc2OC)c2cc(Cl)ccc2-n2c1nnc2C(F)(F)F>>COc1ncccc1[C@H]1O[C@H](CC(=O)O)c2nnc(C(F)(F)F)n2-c2ccc(Cl)cc21,,C1COCCO1,,Cl,O,test
US20090312381A1,O=C(NNC(=O)c1ccc(Cl)cc1)NC1CC1>>O=c1[nH]nc(-c2ccc(Cl)cc2)n1C1CC1,,[Na+],[OH-],Cl,,test
US08981131B2,CC1=C2[C@H]3OC(=O)C(CNCC4C(=O)O[C@H]5C6=C(C)CCC[C@]6(C)CCC45O)C3(O)CC[C@]2(C)CCC1.CCN=C=S>>CCNC(=S)N(CC1C(=O)O[C@H]2C3=C(C)CCC[C@]3(C)CCC12O)CC1C(=O)O[C@@H]2C3=C(C)CCC[C@@]3(C)CCC12O,,C1CCOC1,,Cl,,test
US20110178132A1,Cc1ccccc1-c1ccnc(C#N)c1.NO>>Cc1ccccc1-c1ccnc(C(N)=NO)c1,,CCO,,Cl,O=C([O-])O.[Na+],test
US20150291563A1,CC(=O)c1cccc(B(O)O)c1.OC(C1=NN(c2ccccc2Cl)C(c2ccc(Br)c(F)c2)C1)(C(F)(F)F)C(F)(F)F>>CC(=O)c1cccc(-c2ccc(C3CC(C(O)(C(F)(F)F)C(F)(F)F)=NN3c3ccccc3Cl)cc2F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,CCOC(C)=O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20060241172A1,C[Si](C)(C)C=[N+]=[N-].O=C(O)C1Oc2cc(Cl)cc(Br)c2O1>>COC(=O)C1Oc2cc(Cl)cc(Br)c2O1,,ClCCl,,,,test
US20050054851A1,CC(C)(C)Cn1c(CBr)cc2cnc(C#N)nc21.Oc1ccc(Cl)nc1>>CC(C)(C)Cn1c(COc2ccc(Cl)nc2)cc2cnc(C#N)nc21,,CS(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05500453,CCCC[B-](c1ccccc1)(c1ccccc1)c1ccccc1.C[S+](C)CC#N>>CCCC[B-](c1ccccc1)(c1ccccc1)c1ccccc1.C[S+](C)CC#N,,O,,[I-].[Li+],,test
US06350878B1,C/C=C(\CC)C(C)(C)[C@@H](O)CC(=O)O[C@@H](c1ccccc1)C(O)(c1ccccc1)c1ccccc1>>C/C=C(\CC)C(C)(C)[C@@H](O)CCO.O[C@@H](c1ccccc1)C(O)(c1ccccc1)c1ccccc1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130059858A1,BrCc1ccccc1Br.CC(=O)C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(C(C)(O)Cc2ccccc2Br)CC1,II,CCOCC,,[Mg],,test
US20040077648A1,CN(C)CCN.COc1ccc(N)c(F)c1.Clc1nc(Cl)nc(Cl)n1.NC1CCCCCC1>>COc1ccc(Nc2nc(NCCN(C)C)nc(NC3CCCCCC3)n2)cc1F,,CC#N,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20060135565A1,COCCCOc1ccnc(CS(=O)c2nc3ccccc3[n-]2)c1C>>COCCCOc1ccnc(C[S+]([O-])c2nc3ccccc3[nH]2)c1C,,CCOC(C)=O,,O=C([O-])O.[Na+],,test
US04338251,CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCO.ClCc1ccccc1>>CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCOCc1ccccc1,,CCCCCC,,[K+].[OH-],,test
US20090143353A1,CN(C)[C@H]1CCNC1.Cc1c(-c2ccccc2)c(F)c2oc(C(C)(C)C(N)=O)nc2c1C#N>>Cc1c(-c2ccccc2)c(N2CC[C@H](N(C)C)C2)c2oc(C(C)(C)C(N)=O)nc2c1C#N,,CS(C)=O,O,CCN(CC)CC,CCOC(C)=O,test
US20090274655A1,CC(C)N(C(=O)[C@@H]1CC[C@@H](C)CC1)c1cc(-c2ccc(NC(=O)c3cscn3)cc2)sc1C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O>>CC(C)N(C(=O)[C@@H]1CC[C@@H](C)CC1)c1cc(-c2ccc(NC(=O)c3cscn3)cc2)sc1C(=O)[O-].N=C(N)NCCC[C@H](N)C(=O)O,,CC(C)=O,,,,test
US03944600,CC(C)(Br)C(=O)c1ccc(F)cc1>>CC1Cc2cc(F)ccc2C1=O,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20150191461A1,CC(=O)Cl.Nc1cc(Br)cc(Nc2nccc(C(F)(F)F)n2)c1>>CC(=O)Nc1cc(Br)cc(Nc2nccc(C(F)(F)F)n2)c1,,ClCCl,,O,c1ccncc1,test
US20050075363A1,COc1c(F)cccc1[N+](=O)[O-]>>COc1c(N)cccc1F,[Pd],CO,,,,test
US20040019042A1,CC(=O)Nc1cccc(NS(=O)(=O)c2ccc3c(c2)C(=O)c2cc(S(=O)(=O)Nc4cccc(O)c4)ccc2-3)c1.NO>>CC(=O)Nc1cccc(NS(=O)(=O)c2ccc3c(c2)C(=NO)c2cc(S(=O)(=O)Nc4cccc(O)c4)ccc2-3)c1,,c1ccncc1,,Cl,,test
US20050142413A1,C1COCCO1.C=O.Nc1ccccc1.Oc1ccccc1>>Oc1ccccc1.c1ccc2c(c1)CCNO2,,C1COCCO1,,,,test
US20150232454A1,COC1=CN=CNC1(Cl)OC.OB(O)c1ccc(F)cc1>>COc1ncnc(-c2ccc(F)cc2)c1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150175540A1,CON(C)C(=O)[C@@H]1CC[C@@H](CN2Cc3ccc(O)c(F)c3C2=O)CC1.C[Mg]Br>>CC(=O)[C@@H]1CC[C@@H](CN2Cc3ccc(O)c(F)c3C2=O)CC1,,C1CCOC1,,CCOCC,,test
US04016166,O=C(NCc1ccccc1)c1ccccc1Nc1cccc([N+](=O)[O-])c1.O=C(Nc1cccc(Cl)c1)n1ccnc1>>O=c1c2ccccc2n(-c2cccc([N+](=O)[O-])c2)c(=O)n1Cc1ccccc1,,O,,C1CCOC1,[H-].[Na+],test
US05792766,COc1ccc(-c2nc(-c3ccccc3[N+](=O)[O-])c[nH]2)cc1>>COc1ccc(-c2nc(-c3ccccc3N)c[nH]2)cc1,[Pd],CCO,,,,test
US20120252817A1,C[C@@]1(Cc2ccc(C#N)cc2)C(=O)N(c2cc(Cl)c(F)c(Cl)c2)c2ncc(C(=O)O)n21.O=C(Cl)C(=O)Cl>>C[C@@]1(Cc2ccc(C#N)cc2)C(=O)N(c2cc(Cl)c(F)c(Cl)c2)c2ncc(C(=O)Cl)n21,,ClCCl,,CN(C)C=O,,test
US20050143443A1,CCOC(=O)c1cc(C(=O)Cc2ccc(Cl)cc2)c[nH]1>>CCOC(=O)c1cc(CCc2ccc(Cl)cc2)c[nH]1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20050245503A1,NC1c2ccccc2CCc2ccccc21.S=C=S>>S=C=NC1c2ccccc2CCc2ccccc21,,CCOCC,,CCN(CC)CC,ClCCCl,test
US20140163001A1,CCOC(=O)c1cnn(C(C)(C)C)c1-c1ccc(F)cc1>>CC(C)(C)n1ncc(C(=O)O)c1-c1ccc(F)cc1,,CCO,,[Na+].[OH-],,test
US20090059370A1,Cc1ccc(N)c(N)c1.O=C1C(=O)c2cccc3cccc1c23>>Cc1ccc2nc3c(nc2c1)-c1cccc2cccc-3c12,,O,,CC(=O)O,,test
US04937251,BrC(Br)(Br)Br.OCCCC#CCOCCCc1ccccn1>>BrCCCC#CCOCCCc1ccccn1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04895840,C1CCOC1.CCN(CC)CCN.CO.O=C(O)C(=O)O.O=S(=O)(CCNCCN1CCOCC1)c1ccccc1>>CCN(CC)CCNC(=O)N(CCN1CCOCC1)CCS(=O)(=O)c1ccccc1.O.O=C(O)C(=O)O,,C1CCOC1,CO,CCOCC,,test
US04544667,C1COCCN1.NS(=O)(=O)c1cc2cc(CBr)ccc2o1>>NS(=O)(=O)c1cc2cc(CN3CCOCC3)ccc2o1,,CO,,CCN(CC)CC,,test
US20010051631A1,CCOC(=O)C(F)(F)C(F)(F)F.Cc1nc2cccc3n(CCCCCN)c(=O)c1n23>>Cc1nc2cccc3n(CCCCCNC(=O)C(F)(F)C(F)(F)F)c(=O)c1n23,,CC#N,,CCN(CC)CC,,test
US20150239847A1,Fc1cccnc1Cl.Nc1cc[nH]n1>>Nc1ccn(-c2cccnc2Cl)n1,,CS(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20050288314A1,CC(=O)O.CC(=O)c1ccc(Cl)cc1Br>>CC(=O)OCC(=O)c1ccc(Cl)cc1,,CC#N,,CCN(CC)CC,,test
US20110212946A1,Cn1c(=O)c(CNCC(c2ccccc2)C2CCOCC2)cc2ccccc21.O=C(Cl)C1CCCCC1>>Cn1c(=O)c(CN(CC(c2ccccc2)C2CCOCC2)C(=O)C2CCCCC2)cc2ccccc21,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20020111492A1,CCOC(=O)C1(CCCc2c(F)cnc3ccc(OC)cc23)CCN(CCOc2ccc(F)c(F)c2)CC1>>COc1ccc2ncc(F)c(CCCC3(C(=O)O)CCN(CCOc4ccc(F)c(F)c4)CC3)c2c1,,C1COCCO1,CO,[Na+].[OH-],,test
US05840732,CCCCCCCC=C1SC(=O)N(CCCCSc2cccc3nccn23)C1=O.Cl>>CCCCCCCC=C1SC(=O)N(CCCCSc2cccc3nccn23)C1=O.Cl,,CO,,,,test
US20020019388A1,COC(CN)OC.O=C(Cl)OCc1ccccc1>>COC(CNC(=O)OCc1ccccc1)OC,,Cc1ccccc1,,[Na+].[OH-],,test
US20070021424A1,N.O=C1COC(=O)N1CCCCOc1cccc2ccccc12>>NC(=O)COC(=O)NCCCCOc1cccc2ccccc12,,C1CCOC1,CO,,,test
US20120329818A1,CC1(C(=O)Nc2cccc(Oc3ccc(F)cc3)c2)CCNCC1.Clc1c[nH]c2ncnc(Cl)c12>>CC1(C(=O)Nc2cccc(Oc3ccc(F)cc3)c2)CCN(c2ncnc3[nH]cc(Cl)c23)CC1,,CC(C)O,,CCN(CC)CC,,test
US20110312931A1,BrC1CC1.CC(=O)SC1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(SCC2CC2)CC1,,CC(C)O,O,[Li]O,,test
US20070259898A1,CC(C)(C)OC(=O)N[C@@H](CCC(=O)N(CCOCc1ccccc1)[C@@H]1CC[C@H](C(=O)OCc2ccccc2)CC1)C1CCOCC1>>N[C@@H](CCC(=O)N(CCOCc1ccccc1)[C@@H]1CC[C@H](C(=O)OCc2ccccc2)CC1)C1CCOCC1,,O=C(O)C(F)(F)F,,,,test
US20040138271A1,CCOC(=O)C(Cc1ccc(O)c(CNC(=O)OC(C)(C)C)c1)OC(C)C.O=C1CCC(=O)N1Br>>CCOC(=O)C(Cc1cc(Br)c(O)c(CNC(=O)OC(C)(C)C)c1)OC(C)C,,CC#N,CCOC(C)=O,,,test
US20150080364A1,O=C(CCCCBr)NC1CCN(Cc2ccccc2)CC1>>O=C1CCCCN1C1CCN(Cc2ccccc2)CC1,,C1CCOC1,,[H-].[Na+],,test
US20090036448A1,CNc1cc(Cl)nc(C)n1.N[C@@H]1CC[C@H](NC(=O)c2ccc(F)c(Cl)c2)CC1>>CNc1cc(N[C@@H]2CC[C@H](NC(=O)c3ccc(F)c(Cl)c3)CC2)nc(C)n1,,CCCCO,,O=C([O-])O.[Na+],,test
US20160046653A1,CCCCCc1cccs1.CC[SiH](CC)CC>>CCCCCc1ccc([Si](CC)(CC)CC)s1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US05556864,C(=Cc1ccccc1OCC1CO1)CCc1ccccc1OCc1ccccc1.CNC>>CN(C)CC(O)COc1ccccc1C=CCCc1ccccc1OCc1ccccc1,,C1CCOC1,,,,test
US20070244333A1,BrCc1ccccc1.CCCCC(F)(F)C(O)CC[C@H]1[C@H](OC2CCCCO2)C[C@H](O)[C@@H]1CCCCCCC(=O)O>>CCCCC(F)(F)C(O)CC[C@H]1[C@H](OC2CCCCO2)C[C@H](O)[C@@H]1CCCCCCC(=O)OCc1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20090018103A1,CC(C)(C)OC(=O)N1CCC[C@@H](C(O)c2cccc(Cl)c2F)C1.CCOC(=O)CBr>>CCOC(=O)COC(c1cccc(Cl)c1F)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20160060273A1,CCOC(=O)C1(C)CCN(C2=NOC3(CNC3C)C2)CC1.CCOc1cc(CBr)cc(OCC)c1-c1ccc(F)cc1>>CCOC(=O)C1(C)CCN(C2=NOC3(C2)CN(Cc2cc(OCC)c(-c4ccc(F)cc4)c(OCC)c2)C3C)CC1,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20090042964A1,ClC(Cl)(Cl)Cl.O=C(C(=O)c1ccc(OC(F)F)c(CCO)c1)c1ccccc1>>O=C(C(=O)c1ccc(OC(F)F)c(CCCl)c1)c1ccccc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070197524A1,BrCc1ccccc1.Oc1ccc2c(c1)[nH]c1ccccc12>>c1ccc(COc2ccc3c(c2)[nH]c2ccccc23)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110281838A1,COC(=O)c1ccc(-c2nc(N)nc(C)c2C#Cc2ccc(N)nc2)cc1>>Cc1nc(N)nc(-c2ccc(C(=O)O)cc2)c1C#Cc1ccc(N)nc1,,C1CCOC1,,,,test
US20110039824A1,CC(C)(C#N)c1c[nH]c2cc(F)ccc12>>CC(C)(CN)c1c[nH]c2cc(F)ccc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150018546A1,CCOC(=O)c1c(O)c2cncnc2n(OCc2ccccc2)c1=O.N>>NC(=O)c1c(O)c2cncnc2n(OCc2ccccc2)c1=O,,CCOC(C)=O,,CN(C)C=O,Cl,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(CCO[Si](C)(C)C(C)(C)C)c2ncnn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(CCO)c2ncnn12,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US20060079687A1,O=C(OO)c1cccc(Cl)c1.O=Cc1cc(Sc2cccc(NS(=O)(=O)c3ccccc3)c2)ccc1[N+](=O)[O-]>>O=Cc1cc(S(=O)c2cccc(NS(=O)(=O)c3ccccc3)c2)ccc1[N+](=O)[O-],,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20070155805A1,CCCCC(CCOc1ccc(OCC(=O)OCC)c(C)c1)c1sc2cc(F)ccc2c1C>>CCCCC(CCOc1ccc(OCC(=O)O)c(C)c1)c1sc2cc(F)ccc2c1C,,CO,,[Na+].[OH-],,test
US08828991B2,COC(=O)c1sc(C#CC2CC2)cc1[N+](=O)[O-]>>COC(=O)c1sc(CCC2CC2)cc1N,[Pd],CO,,,,test
US03951976,CN(C(=O)Cl)c1cccc(CCl)c1.CN1CCC(O)N(c2nnc(C(F)(F)F)s2)C1=O>>CN1CCC(OC(=O)N(C)c2cccc(CCl)c2)N(c2nnc(C(F)(F)F)s2)C1=O,,Cc1ccccc1,,c1ccncc1,,test
US20110257100A1,CCNC(=O)N1CC(N(CC(=O)OCC)Cc2ccc(-c3cc4nccc(Oc5ccc(NC(=O)NC6CC6)cc5F)c4s3)nc2)C1>>CCNC(=O)N1CC(N(CC(=O)O)Cc2ccc(-c3cc4nccc(Oc5ccc(NC(=O)NC6CC6)cc5F)c4s3)nc2)C1,,CO,,[Na+].[OH-],,test
US05244597,CCCCCC[C@@H](C)OC(=O)c1ccc(-c2ccc(C3CCC(=O)CC3)cc2)cc1>>CCCCCC[C@@H](C)OC(=O)c1ccc(-c2ccc([C@@H]3CC[C@@H](O)CC3)cc2)cc1,,COCCOC,,Cl,[BH4-].[Na+],test
US20070049618A1,COc1ccc(Nc2cccc(C(=O)O)c2C(=O)O)c(OC)c1.C[C@]1(N)CCC(=O)NC1=O>>COc1ccc(Nc2cccc3c2C(=O)N([C@@]2(C)CCC(=O)NC2=O)C3=O)c(OC)c1,,c1ccncc1,,Br,,test
US20130203815A1,CCOC(=O)C1C(=O)N(C)CC1c1c(OC)cc(OC)cc1OC>>COc1cc(OC)c(C2CN(C)C(=O)C2CO)c(OC)c1,,CCO,,[BH4-].[Na+],,test
US20160200725A1,COc1cc(OC)c(Cl)c(-c2cc3cnc(SC)nc3n(CCNC3CN(C(=O)OC(C)(C)C)C3)c2=O)c1Cl.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1cc(OC)c(Cl)c(-c2cc3cnc(SC)nc3n(CCN(C(=O)C(F)(F)F)C3CN(C(=O)OC(C)(C)C)C3)c2=O)c1Cl,CN(C)c1ccncc1,ClCCl,,O,,test
US06300352B1,C[C@H](Oc1ccc(B(O)O)cc1)[C@H](O)CCc1cccnc1.N#Cc1ccc(Br)cc1Cl>>C[C@H](Oc1ccc(-c2ccc(C#N)c(Cl)c2)cc1)[C@H](O)CCc1cccnc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20080146644A1,O=C1CCC/C(=N\Nc2ccccc2)C1>>O=C1CCCc2[nH]c3ccccc3c21,,O=C(O)C(F)(F)F,,,,test
US20120149718A1,N=C(n1ccnc1)n1ccnc1.Nc1ccc(F)cc1O>>Nc1nc2ccc(F)cc2o1,,C1CCOC1,CCOC(C)=O,,,test
US20110245205A1,COC(=O)c1ccc(C(C)(O)c2ncc(-c3cc(C)cc(Nc4nccc(C(F)(F)F)n4)c3)s2)cn1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C(C)(O)c3ccc(C(=O)O)nc3)s2)c1,,CO,O,Cl,[Na+].[OH-],test
US20040009995A1,CC(C)(C)OC(=O)CBr.COc1cc(C)c(Br)c(CO)c1>>COc1cc(C)c(Br)c(COCC(=O)OC(C)(C)C)c1,,CN(C)C=O,O,[H-].[Na+],,test
US20120214762A1,Cn1cccc(OCc2ccccc2)c1=O>>Cn1cccc(O)c1=O,[Pd],CO,,[H][H],,test
US20140088234A1,ClCCl.O=C(O)C(Cl)Cl>>ClCCl.O=C(O)C(Cl)Cl,,ClCCl,,,,test
US20090275611A1,C=O.O=S(=O)(c1ccccc1)c1ccc(CNC[C@H](O)c2ccccc2)cc1>>CN(Cc1ccc(S(=O)(=O)c2ccccc2)cc1)C[C@H](O)c1ccccc1,,C1CCOC1,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100168094A1,O=[N+]([O-])c1ccc(C2=CCCC2)cc1>>Nc1ccc(C2CCCC2)cc1,[Pd],CO,ClCCl,,,test
US20110269738A1,CCc1c(C=O)cccc1-c1nnc(-c2ccc(OC(C)C)c(Cl)c2)s1.O=C(O)C1CCNC1>>CCc1c(CN2CCC(C(=O)O)C2)cccc1-c1nnc(-c2ccc(OC(C)C)c(Cl)c2)s1,,CCO,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130059834A1,Cn1nc(-c2cnc3c(n2)c(C(=O)N[C@H]2CC[C@@H](CC#N)C2)cn3COCC[Si](C)(C)C)c2ccc(F)cc21>>Cn1nc(-c2cnc3[nH]cc(C(=O)N[C@H]4CC[C@@H](CC#N)C4)c3n2)c2ccc(F)cc21,,ClCCl,,NCCN,O=C(O)C(F)(F)F,test
US20120165331A1,COC(=O)C1(NCCNC(=O)OC(C)(C)C)CCN(Cc2ccccc2)CC1>>O=C1NCCNC12CCN(Cc1ccccc1)CC2,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20090118500A1,COC(=O)c1ccc(C(=O)NCc2ccnn2C)s1.NN>>Cn1nccc1CNC(=O)c1ccc(C(=O)NN)s1,,CO,,O,,test
US20110306626A1,CC(C)(C)OC(=O)CN1C(=O)C2(CCCC2)N=C1c1cc(F)cc(F)c1.Cl>>Cl.O=C(O)CN1C(=O)C2(CCCC2)N=C1c1cc(F)cc(F)c1,,CCOC(C)=O,,,,test
US06121280,CCOC(OCC)C(=O)C=CCCc1cc(OC)c(OC)c(OC)c1>>CCOC(CCCc1cc(OC)c(OC)c(OC)c1)(OCC)C(C)=O,[Pd],CCO,,,,test
US20090221576A1,CS(=O)(=O)O.N#Cc1ccc2[nH]c(O)c(-c3ccc(CN4CCOCC4)cn3)c2c1>>CS(=O)(=O)O.N#Cc1ccc2[nH]c(O)c(-c3ccc(CN4CCOCC4)cn3)c2c1,,CCO,,,,test
US05128348,CC1=C(c2ccc(C(C)(C)C)cc2)CCC1=O>>CC1=C(c2ccc(C(C)(C)C)cc2)CCC1O,,C1CCOC1,CCOCC,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080027077A1,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(Br)o1>>COC(=O)C=Cc1ccc(Br)o1,,Cc1ccccc1,,O,,test
US20140274930A1,CC1(C)OC[C@H]([C@H]2OC(=O)[C@@]3(CI)OC(C)(C)O[C@@H]23)O1>>CC1(C)OC[C@H]([C@H]2OC(=O)[C@@]3(C)OC(C)(C)O[C@@H]23)O1,[Pd],CCO,,CCN(CC)CC,,test
US06083943,COC(=O)[C@H]1[C@H](N)[C@H](c2ccccc2)N(C(=O)OCc2ccccc2)[C@@H]1C.COc1ccc(OC(F)(F)F)cc1C=O>>COC(=O)[C@@H]1[C@H](NCc2cc(OC(F)(F)F)ccc2OC)[C@H](c2ccccc2)N(C(=O)OCc2ccccc2)[C@@H]1C,,ClCCl,,[Na+].[OH-],,test
US20090226377A1,CN(C)C=Nc1ccc(Br)cc1C#N.Cc1cc(F)c(N)cc1O>>Cc1cc(F)c(Nc2ncnc3ccc(Br)cc23)cc1O,,CC(=O)O,,,,test
US20100273764A1,COc1ccc(Nc2nc(N3CCCC3)ncc2-c2nc(C)nc(SC)n2)cn1.N>>COc1ccc(Nc2nc(N3CCCC3)ncc2-c2nc(C)nc(N)n2)cn1,,C1COCCO1,,,,test
US05571774,CCOC(=O)c1cc([N+](=O)[O-])c[n+]([O-])c1C(=O)OCC>>CCOC(=O)c1cc([N+](=O)[O-])cnc1C(=O)OCC,,ClCCCl,,ClP(Cl)Cl,,test
US20110207940A1,Cn1nc(C(F)F)c(C=O)c1Cl.[F-]>>Cn1nc(C(F)F)c(C=O)c1F,,CN(C)C=O,,O,,test
US20020165241A1,Fc1cnc(Cl)nc1.NCC1CCN(C(=O)OCc2ccc(C3CC3)cc2)CC1>>O=C(OCc1ccc(C2CC2)cc1)N1CCC(CNc2ncc(F)cn2)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US20130303533A1,COCCn1ccc2c(Cl)nc(S(=O)(=O)c3ccc(F)cc3)nc21.Nc1cc[nH]n1>>COCCn1ccc2c(Nc3cc[nH]n3)nc(S(=O)(=O)c3ccc(F)cc3)nc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20100292208A1,C[Si](C)(C)N=C=O.c1cnc2nc(Oc3ccc4c(CN5CCNCC5)coc4c3)sc2c1>>NC(=O)N1CCN(Cc2coc3cc(Oc4nc5ncccc5s4)ccc23)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US05380460,CCCCCCCCBr.N#Cc1ccccc1O>>CCCCCCCCOc1ccc(C#N)cc1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05719141,CS(=O)(=O)c1cnc2ccccc2c1>>CS(=O)(=O)C1CNc2ccccc2C1,O=[Pt],CC(=O)O,,,,test
US05852213,CCCCCCCCC(=O)Cl.O=C1N[C@@H](Cc2ccccc2)CO1>>CCCCCCCCC(=O)N1C(=O)OC[C@@H]1Cc1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US20130338140A1,CC(C)(C)OC(=O)N1CCC[C@@H]1CC(O)c1ccc(F)c(Cl)c1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)N1CCC[C@@H]1CC(c1ccc(F)c(Cl)c1)N1C(=O)c2ccccc2C1=O,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080269219A1,Cc1nccn1-c1nc(-c2ccc(Cl)cc2)c(CCCOS(C)(=O)=O)o1.N#CCc1ccc(O)cc1>>Cc1nccn1-c1nc(-c2ccc(Cl)cc2)c(CCCOc2ccc(CC#N)cc2)o1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080146595A1,CC(Br)c1ccccc1.Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCNCC2)ncc1Br>>Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(C(C)c3ccccc3)CC2)ncc1Br,,CC#N,,O=C(O)C(F)(F)F,,test
US20140296203A1,O=C([O-])N[C@@H]1CNC[C@H]1c1ccccc1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>N[C@@H]1CN(CC(F)(F)F)C[C@H]1c1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20050159391A1,Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)cc1NC(=O)n1ccc2c(Cl)ncnc21.NC(=O)c1cccc(N)c1>>Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)cc1NC(=O)n1ccc2c(Nc3cccc(C(N)=O)c3)ncnc21,,CCCCO,,CC(=O)Cl,,test
US20140142083A1,CCc1c(C(=O)O)cc(Cl)cc1N(CC)C1CCOCC1.Cc1cc(C)c(CN)c(=O)[nH]1>>CCc1c(C(=O)NCc2c(C)cc(C)[nH]c2=O)cc(Cl)cc1N(CC)C1CCOCC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030055244A1,COc1ccc(CN2C(=O)CC3(CCN(Cc4ccccc4)CC3)C2=O)cc1>>COc1ccc(CN2CCC3(CCN(Cc4ccccc4)CC3)C2)cc1,,C1CCOC1,,,,test
US20040030197A1,CCN(CC)CCOc1ccc(Cc2ccccc2)cc1.Cc1cccc(Br)c1C>>Cc1cc(O)cc(Br)c1C,,C1CCCCC1,,Cl,,test
US20140088075A1,C=C(C)OC(=O)Cl.CCn1c(=O)c(-c2cc(N)c(F)cc2C)cc2cnc(Cl)cc21>>C=C(C)OC(=O)Nc1cc(-c2cc3cnc(Cl)cc3n(CC)c2=O)c(C)cc1F,,CCOC(C)=O,,O=C([O-])O.[Na+],,test
US20140179667A1,CC(C)I.O=C1NCCc2cc(F)c(O)c(Cl)c21>>CC(C)Oc1c(F)cc2c(c1Cl)C(=O)NCC2,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05258513,C1COCCN1.CCCc1nc(Cl)nc(NC2CC2)n1>>CCCc1nc(NC2CC2)nc(N2CCOCC2)n1,,C1COCCO1,,,,test
US20040067981A1,BrC(Br)(Br)Br.C=Cc1cc(OC(=O)N(C)C)ccc1C(O)CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>C=Cc1cc(OC(=O)N(C)C)ccc1C(O)(Br)CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04271188,CC(=O)OC(C)=O.CCOC(=O)c1ccc(NCc2ccc(Cl)cc2)cc1>>CCOC(=O)c1ccc(N(Cc2ccc(Cl)cc2)C(C)=O)cc1,O=S(=O)(O)O,O,,O=C([O-])O.[Na+],,test
US20030171587A1,CC(C)(C)OC(=O)NCCC1CCNC1.CCOC(=O)c1cc(CC)c2c(OC)c(Cl)ccn2c1=O>>CCOC(=O)c1cc(CC)c2c(OC)c(N3CCC(CCNC(=O)OC(C)(C)C)C3)ccn2c1=O,,CC#N,,CCN(CC)CC,,test
US20060147747A1,Nc1ccc(Br)cc1.O=[N+]([O-])c1ccccc1Br>>O=[N+]([O-])c1ccccc1Nc1ccc(Br)cc1,,CCOC(C)=O,,CC(=O)[O-].[Na+],,test
US20050250836A1,O=Cc1c(Cl)c2c3c(c(-c4ccccc4Cl)cc2n1CCCO)C(=O)NC3=O>>O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c(Cl)c(CO)n1CCCO,,C1CCOC1,,CSC,,test
US20070282101A1,COC(=S)Nc1cc(-c2cc3ccccc3s2)c2[nH]ncc2c1.NCCc1ccccn1>>O=C(NCCc1ccccn1)Nc1cc(-c2cc3ccccc3s2)c2[nH]ncc2c1,,CCO,,,,test
US20050026931A1,CCS(=O)(=O)c1ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c(Cl)c1F.CN1CCNCC1>>CCS(=O)(=O)c1ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c(Cl)c1N1CCN(C)CC1,,CN1CCCC1=O,,[Cl-].[NH4+],,test
US20100298288A1,CC(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)NCOC(=O)N4CCCOCC4)cc3)oc12>>CC(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)NC[C@@H]4CCNCCO4)cc3)oc12,[Pd],,,CO,,test
US20120040983A1,CC1CCCN1.Clc1nncc2cc(Br)ccc12>>CC1CCCN1c1nncc2cc(Br)ccc12,,CN(C)C=O,CO,,,test
US04459407,CC(C)(C)C(=O)OCCl.O=C1C(=O)N(Cc2ccc(Nc3ncccn3)cc2)CCN1Cc1ccccc1>>CC(C)(C)C(=O)OCN(c1ccc(CN2CCN(Cc3ccccc3)C(=O)C2=O)cc1)c1ncccn1,,CN(C)C=O,,[H-].[Na+],,test
US20150284321A1,Cc1ccccc1S(=O)(=O)Cl.Nc1cccc(NC(=O)Nc2ccccc2)c1>>Cc1ccccc1S(=O)(=O)Nc1cccc(NC(=O)Nc2ccccc2)c1,,CCOC(C)=O,,CCN(CC)CC,,test
US20160046648A1,FC(F)(F)c1ccccc1C1CCNCC1.O=C1CCC(=O)O1>>O=C(O)CCC(=O)N1CCC(c2ccccc2C(F)(F)F)CC1,,ClCCl,,Cl,,test
US20160052940A1,C1O[C@@H]2CN[C@H]1C2.FC(F)(F)Cc1nc(Cl)cc(Cl)n1>>FC(F)(F)Cc1nc(Cl)cc(N2C[C@@H]3C[C@H]2CO3)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20080280925A1,COc1ccccc1Cn1nc(C)c2c(C(F)(F)F)nn(C3CCN(C(=O)OCc4ccccc4)CC3)c2c1=O>>COc1ccccc1Cn1nc(C)c2c(C(F)(F)F)nn(C3CCNCC3)c2c1=O,[Pd],CCO,,,,test
US20010034357A1,C[C@@H](COc1ccc(Cl)nc1)N(C)C.Cc1ccc(S(=O)(=O)O)cc1>>C[C@@H](COc1ccc(Cl)nc1)N(C)C.Cc1ccc(S(=O)(=O)O)cc1,,CCOC(C)=O,,CCOCC,O,test
US20090274632A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=[N+]([O-])c1cn[nH]c1>>Cc1ccc(S(=O)(=O)n2cc([N+](=O)[O-])cn2)cc1,,CN(C)C=O,O,CCN(CC)CC,,test
US20150031715A1,COC(=O)[C@H](Cc1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1)NC(=O)c1c(Cl)cc(OCCCNC(=O)OC(C)(C)C)cc1Cl>>COC(=O)[C@H](Cc1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1)NC(=O)c1c(Cl)cc(OCCCN)cc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160137636A1,O=C1CCC(=O)N1Br.O=c1cn[nH]c2cc(SCc3ccccc3)ccc12>>O=c1c(Br)n[nH]c2cc(SCc3ccccc3)ccc12,,O,,CS(C)=O,,test
US20110306599A1,CNc1ccc2cc(-c3n[nH]c4c3CCC(C)(C)C4)[nH]c2c1.O=C(O)CN1CCOCC1=O>>CN(C(=O)CN1CCOCC1=O)c1ccc2cc(-c3n[nH]c4c3CCC(C)(C)C4)[nH]c2c1,,c1ccncc1,,CCN=C=NCCCN(C)C,Cl,test
US20160235734A1,O=C(O)[C@](O)(c1ccccc1)c1cccc(OCCCCC2OCCO2)c1.OCC1CCN(Cc2ccccc2)CC1>>O=C(OCC1CCN(Cc2ccccc2)CC1)[C@](O)(c1ccccc1)c1cccc(OCCCCC2OCCO2)c1,,CCOC(C)=O,CN(C)C=O,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US20070249670A1,COC(=O)[C@@H](NC(=O)c1ccc(Cl)cc1N)C1CCCCC1.Cc1cccc(Cl)c1N=C=O>>COC(=O)[C@@H](NC(=O)c1ccc(Cl)cc1NC(=O)Nc1c(C)cccc1Cl)C1CCCCC1,,c1ccncc1,,,,test
US20130336920A1,CC(=O)N1CCNCC1.O=C(NCc1cccc(C(F)(F)F)c1)c1ccnc(-c2cc(N3CCCCC3)ccc2NC(=O)c2cccc(CCl)n2)c1>>CC(=O)N1CCN(Cc2cccc(C(=O)Nc3ccc(N4CCCCC4)cc3-c3cc(C(=O)NCc4cccc(C(F)(F)F)c4)ccn3)n2)CC1,,CN(C)C=O,,[I-].[K+],,test
US20070117822A1,C=CC#N.O=Cc1cc(-c2ccccc2)cnc1Cl>>C=C(C#N)C(O)c1cc(-c2ccccc2)cnc1Cl,,CCOCC,,C1CN2CCN1CC2,,test
US20060142335A1,CCCCCCCN=C=O.Oc1ccc2c(c1)CCCN2Cc1ccccc1>>CCCCCCCNC(=O)Oc1ccc2c(c1)CCCN2Cc1ccccc1,,C1CCOC1,,c1ccncc1,,test
US20160032047A1,CC(=O)OC(C)=O.COc1cc(C(=O)O)ccc1O>>COc1c(O)ccc(C(=O)O)c1C(C)=O,,O,,Cl,c1ccncc1,test
US20160096828A1,CCc1cccc(N=C=O)c1.NC(=O)n1c(-c2cccc(N)c2)cc2ccccc21>>CCc1cccc(NC(=O)Nc2cccc(-c3cc4ccccc4n3C(N)=O)c2)c1,,C1CCOC1,CCOC(C)=O,,,test
US20100113421A1,CC(C)C(=O)Cl.CC1(C)OC(=O)CC(=O)O1>>CC(C)C(O)=C1C(=O)OC(C)(C)OC1=O,,ClCCl,,c1ccncc1,,test
US20100144852A1,CC(C)=O.CNC.OC1CC2CCC2C1Br>>CN(C)C1C2CC(O)C1CC2=O,,CC(C)=O,,C1CCOC1,,test
US20120041019A1,CCC(C)(C)[Mg]Cl.CCOC(=O)[C@@H]1CCCCN1C(=O)C(=O)OC>>CCOC(=O)[C@@H]1CCCCN1C(=O)C(=O)C(C)(C)CC,,C1CCOC1,,[Cl-].[NH4+],,test
US20090227602A1,CC(C)c1nc(-c2ccc(F)cc2)c(-c2ccnc(Nc3ccccc3)n2)n1/C=C/C=O.CCOC(=O)CC(C)=O>>CCOC(=O)CC(=O)CC(O)C=Cn1c(C(C)C)nc(-c2ccc(F)cc2)c1-c1ccnc(Nc2ccccc2)n1,,C1CCOC1,,[Li]CCCC,[H-].[Na+],test
US20030036655A1,Cc1ccc(C(=O)c2ccc([N+](=O)[O-])cc2)cc1.O=C1CCC(=O)N1Br>>O=C(c1ccc(CBr)cc1)c1ccc([N+](=O)[O-])cc1,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20160039780A1,CN(C)C(OC(C)(C)C)OC(C)(C)C.O=C(O)CCC12CCC(O)(CC1)CC2>>CC(C)(C)OC(=O)CCC12CCC(O)(CC1)CC2,,Cc1ccccc1,,,,test
US20160108016A1,CCCCCCC(C)(C)c1cc(OC(C)=O)c2c(c1)OC(C)(C)[C@@H]1CCC(=O)OC[C@@H]21>>CCCCCCC(C)(C)c1ccc2c(c1)OC(C)(C)[C@H](CCO)[C@H]2CC(=O)O,,O,,C1CCOC1,[Li+].[OH-],test
US20140128383A1,NNCc1ccccc1.O=C(CC(=O)C(F)(F)F)c1ccc2c(c1)CCCO2>>FC(F)(F)c1cc(-c2ccc3c(c2)CCCO3)n(Cc2ccccc2)n1,,CC#N,,Cl,Cl,test
US20120252721A1,CC(C)(C)OC(=O)N1CCC[C@H]1c1nc(Br)c[nH]1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCC[C@H]1c1ncc(Br)n1C(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,ClCCl,CCN(CC)CC,O,test
US20070254937A1,CC(C)(C)[Si](C)(C)Cl.OCc1cc(Br)cs1>>CC(C)(C)[Si](C)(C)OCc1cc(Br)cs1,,ClCCl,,c1c[nH]cn1,,test
US20140155389A1,BrCCBr.Clc1cccc(Cl)c1CBr.[Zn]>>Clc1cccc(Cl)c1C[Zn+].[Br-],,C1CCOC1,,C[Si](C)(C)Cl,,test
US20160272645A1,C=CC(=O)Cl.N#Cc1cc(-c2nn(CCNCc3ccccc3)c3ncnc(N)c23)cc(O)c1F>>C=CC(=O)N(CCn1nc(-c2cc(O)c(F)c(C#N)c2)c2c(N)ncnc21)Cc1ccccc1,,ClCCl,,,,test
US20040106604A1,C=O.O=C(O)CCC(=O)c1ccccc1>>O=C1CC(C(=O)c2ccccc2)CO1,,O,,Cl,O=C([O-])[O-].[K+].[K+],test
US04683303,COC(=O)C(=O)N1C(=O)[C@@H](NC(=O)OCc2ccccc2)[C@@H]1OC(C)=O>>CC(=O)O[C@@H]1NC(=O)[C@H]1NC(=O)OCc1ccccc1,,CO,,O,,test
US20150239907A1,Cc1cc2c(C#N)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)COCC2.Clc1nc2c(c(NCc3ccccc3)n1)CCCC2>>Clc1nc2c(c(NCc3ccccc3)n1)COCC2,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20120238545A1,O=C(c1nn(-c2ccccc2)cc1[N+](=O)[O-])N1CCOCC1>>Nc1cn(-c2ccccc2)nc1C(=O)N1CCOCC1,[Pd],CCOC(C)=O,,,,test
US20090131457A1,Cn1nc(Br)c2c(Cl)nc(N)nc21.NCCN1CCOCC1>>Cn1nc(Br)c2c(NCCN3CCOCC3)nc(N)nc21,,ClCCl,O,CN(C)C=O,,test
US20130023545A1,COc1c(C)cc(-c2nc3cnc(Cl)nc3o2)cc1C>>Cc1cc(-c2nc3cnc(Cl)nc3o2)cc(C)c1O,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20150065705A1,O=c1nc(N2CC=C(c3ccc(F)cc3)C(O)C2)ncn1Cc1ccc(Cl)cc1>>O=c1nc(N2CCC(c3ccc(F)cc3)C(O)C2)ncn1Cc1ccc(Cl)cc1,[Pd],ClCCl,,CO,[H][H],test
US20060122173A1,COc1cc(Cl)cc2c1NC(Nc1ccccc1Cl)=NS2(=O)=O>>Oc1cc(Cl)cc2c1NC(Nc1ccccc1Cl)=NS2,,ClCCl,,BrB(Br)Br,,test
US05583137,COc1ccc(CC2NCCc3cc(OC)c(OC)cc32)cc1OC.ClCCl.Clc1nc(Cl)c2[nH]cnc2n1>>COc1ccc(CC2c3cc(OC)c(OC)cc3CCN2c2nc(Cl)nc3c2ncn3C)cc1OC,,ClCCl,,CCN(CC)CC,Cl,test
US20020013465A1,CCCc1nn(C)c(C(N)=O)c1N.CCOc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1C=O>>CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12,[Pd],Cc1ccccc1C,,,,test
US20160130229A1,C1=C(N2CCOCC2)CCCC1.N#CC1=C(N)SC(N)=C(C#N)C1c1ccc(Cl)cc1>>N#Cc1c(S)nc2c(c1-c1ccc(Cl)cc1)CCCC2,,CCO,,Cl,,test
US20020193367A1,CN(C)c1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1F>>CN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1F,[Pd],,,,,test
US06048872,COC(=O)COc1c(F)cc([N+](=O)[O-])cc1F>>COC(=O)COc1c(F)cc(N)cc1F,[Pd],C1CCOC1,,[H][H],,test
US20020156081A1,CC1(C)OB(c2ccc(C(C#N)c3ccccc3)cc2)OC1(C)C.CN1CCN([C@H]2CC[C@@H](n3nc(I)c4c(N)ncnc43)CC2)CC1>>CN1CCN([C@@H]2CC[C@H](n3nc(-c4ccc(C(C#N)c5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20160200692A1,CSc1c(Cl)cc(F)c(C(=O)Cl)c1Cl.Cn1cnnc1N>>CSc1c(Cl)cc(F)c(C(=O)Nc2nncn2C)c1Cl,,C1CCOC1,,[Li]CCCC,,test
US20020019413A1,CCOC(=O)c1cn(C)c2nc(OC)c(I)cc2c1=O>>COc1nc2c(cc1I)c(=O)c(C(=O)O)cn2C,,CO,,Cl,[Na+].[OH-],test
US20090023746A1,Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC3CC3)cc(C(=O)O)c2c1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC3CC3)cc(CO)c2c1,,C1CCOC1,,B,,test
US20160024044A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNC[C@@H](c1ccc2ccccc2c1)[C@@H](O)c1ccccc1>>CN(C[C@@H](c1ccc2ccccc2c1)[C@@H](O)c1ccccc1)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,Cl,test
US04507492,C=CCOC(=O)OC.O=Cc1ccc(O)cc1>>C=CCOc1ccc(C=O)cc1,[Pd],,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140000807A1,CO[Si](CCCN)(OC)OC.O=C(N=C=S)c1ccccc1>>CCC[Si](OC)(OC)OC.NC(=S)NC(=O)c1ccccc1,,ClCCl,,,,test
US04859229,CC(C)Oc1cc(N=C=O)c(F)cc1Cl.CCOC(=O)C(C)=C(N)CC>>CCOC(=O)C(C)=C(CC)NC(=O)Nc1cc(OC(C)C)c(Cl)cc1F,,CCOCC,,,,test
US04628083,Nc1ccc(S(=O)(=O)Nc2ccccn2)cc1.O=C(O)Cc1ccccc1O.O=N[O-]>>O=C(O)Cc1cc(N=Nc2ccc(S(=O)(=O)Nc3ccccn3)cc2)ccc1O,,Cl,O,[Na+].[OH-],,test
US08569490B2,C=C1C(CO)C(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)CC1n1cnc2c(Cl)nc(N)nc21>>C=C1C(CO)C(O)CC1n1cnc2c(Cl)nc(N)nc21,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20070021442A1,COc1cc(F)cc(OC)c1>>COc1cc(O)cc(F)c1,,ClCCl,,BrB(Br)Br,,test
US05462954,C=CCOc1cccc(Oc2ccc(C(=O)OC)cc2)c1>>C=CCc1ccc(Oc2ccc(C(=O)OC)cc2)cc1O,,CCOC(C)=O,,CN(C)c1ccccc1,,test
US20090203908A1,CCOC(=O)C(C)Br.COc1ccc(N2CCN(Cc3nc(-c4ccc(C(F)(F)F)cc4)sc3CCC(=O)c3ccc(O)c(C)c3)CC2)cc1>>CCOC(=O)C(C)Oc1ccc(C(=O)CCc2sc(-c3ccc(C(F)(F)F)cc3)nc2CN2CCN(c3ccc(OC)cc3)CC2)cc1C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150065482A1,CCOC(=O)C=[N+]=[N-].O=C1CCOCC1>>CCOC(=O)C(=[N+]=[N-])C1(O)CCOCC1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20130330366A1,CCOC(=O)c1cc(O)n(-c2ccccn2)n1>>O=C(O)c1cc(O)n(-c2ccccn2)n1,,O,,CO,,test
US06288096B1,CC(C)(C)OC(=O)Nc1ccc(CCO)cc1.O=[N+]([O-])c1cccc(S(=O)(=O)Cl)c1>>CC(C)(C)OC(=O)Nc1ccc(CCOS(=O)(=O)c2cccc([N+](=O)[O-])c2)cc1,,ClCCl,,,,test
US20140213554A1,CC(C)(C)OC(=O)Nc1cnc2c(c1)cc(Br)n2S(=O)(=O)c1ccccc1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1cnc2c(c1)cc(Br)n2S(=O)(=O)c1ccccc1,CN(C)c1ccncc1,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20140371269A1,Br[Mg]C1CC1.CON(C)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(C(=O)C2CC2)CC1,,C1CCOC1,,,,test
US04962103,CC(=O)S[C@H]1C[C@@H](CC(=O)O)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1.ClCCl>>COC(=O)C[C@@H]1C[C@H](SC(C)=O)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1,,ClCCl,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20020049201A1,CCC(CC)ONC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>CCC(CC)ON(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc([N+](=O)[O-])cc1,CN(C)c1ccccn1,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20060189613A1,COc1ncncc1N.O=S(=O)(Cl)c1cccc(Cl)c1Cl>>COc1ncncc1NS(=O)(=O)c1cccc(Cl)c1Cl,,c1ccncc1,,,,test
US20160068532A1,Brc1cc2[nH]ncc2nc1Br.C=C[Sn](CCCC)(CCCC)CCCC>>C=Cc1nc2cn[nH]c2cc1Br,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,,,test
US20080146612A1,COC(=O)c1cc(Cl)cnc1-c1ccc(Cl)c(C(=O)NCCC2CCCCC2)c1>>O=C(NCCC1CCCCC1)c1cc(-c2ncc(Cl)cc2C(=O)O)ccc1Cl,,CO,O,[Na+].[OH-],,test
US04205079,C=CCN.CCOC(=O)C1COc2ccc(NC(C)=O)cc2O1>>C=CCNC(=O)C1COc2ccc(NC(C)=O)cc2O1,,CCO,,,,test
US20090257978A1,COc1ccc2c(Cl)cc(-n3ccc(NC(C)C)n3)nc2c1.O>>COc1ccc2c(O)cc(-n3ccc(NC(C)C)n3)nc2c1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US04698337,Cl.O=CNc1nc(C(=NOCCOC=O)C(=O)NC2C(=O)N3C(C(=O)O)=C(CSc4nncs4)CS[C@H]23)cs1>>Cl.Nc1nc(C(=NOCCO)C(=O)NC2C(=O)N3C(C(=O)O)=C(CSc4nncs4)CS[C@H]23)cs1,,CO,,C1CCOC1,,test
US04914200,CC(=O)O.C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1C(=O)N[C@@H]1O[Si](C)(C)C>>CC(=O)O[C@H]1NC(=O)[C@@H]1[C@@H](C)O[Si](C)(C)C(C)(C)C,CN(C)c1ccncc1,CCOC(C)=O,,CC(=O)OC(C)=O,,test
US20020016337A1,O=C(Cl)OCc1ccccc1.OCC1CCCCNC1>>O=C(OCc1ccccc1)N1CCCCC(CO)C1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20060173019A1,COCN(c1cc(Cl)cnc1C1OC(=O)c2cccc(Cl)c21)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1>>O=C1OC(c2ncc(Cl)cc2NS(=O)(=O)c2ccc(Cl)c(C(F)(F)F)c2)c2c(Cl)cccc21,,C1COCCO1,Cl,O,,test
US05043439,O=C(COc1ccccc1)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(OS(=O)(=O)C(F)(F)F)CS[C@H]12.Sc1nc2ccccc2s1>>O=C(COc1ccccc1)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(Sc3nc4ccccc4s3)CS[C@H]12,,C1CCOC1,,[H-].[Na+],,test
US04699992,CN(C)C=C(C#N)C(=O)c1cc(F)c(Cl)cc1Cl.NC1CC1>>N#CC(=CNC1CC1)C(=O)c1cc(F)c(Cl)cc1Cl,,Cc1ccccc1,,,,test
US05635527,CCOC(=O)COc1ccc(N)cc1.N#Cc1ccc2oc(C(=O)O)cc2c1>>CCOC(=O)COc1ccc(NC(=O)c2cc3cc(C#N)ccc3o2)cc1,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20080207708A1,COC(=O)c1ccc2[nH]c(-c3coc(Cc4cc(Cl)ccc4OCc4ccccc4)n3)nc2c1>>OCc1ccc2[nH]c(-c3coc(Cc4cc(Cl)ccc4OCc4ccccc4)n3)nc2c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060148858A1,COCOCCCc1c[nH]nc1C(C)C.CSc1ncc(C#N)cn1>>CC(C)c1nn(-c2ncc(C#N)cn2)cc1CCCO,,CN(C)C=O,O,[H][H],[H-].[Na+],test
US20160075692A1,ClCc1nnc(C2CC2)o1.O=C1NCCN1c1cccc2c1cnn2-c1ccccc1F>>O=C1N(Cc2nnc(C3CC3)o2)CCN1c1cccc2c1cnn2-c1ccccc1F,,C1CCOC1,,[H-].[Na+],,test
US20090312335A1,CCOC(=O)c1cn2c(c1OC)C(=O)N(C)CC2>>COc1c(C(=O)O)cn2c1C(=O)N(C)CC2,,CCO,,Cl,[Na+].[OH-],test
US20030096788A1,CC(C)(C)c1nnc([C@H]2O[C@@H](n3cnc4c(Cl)ncnc43)[C@H](O)[C@@H]2O)o1.NC1CCOCC1>>CC(C)(C)c1nnc([C@H]2O[C@@H](n3cnc4c(NC5CCOCC5)ncnc43)[C@H](O)[C@@H]2O)o1,,CC(C)O,,CCN(C(C)C)C(C)C,Cl,test
US20100130556A1,CCOC(=O)C=Cc1cccc(NC(=O)c2ccc(C(=O)c3ccccc3)o2)c1>>O=C(O)C=Cc1cccc(NC(=O)c2ccc(C(=O)c3ccccc3)o2)c1,,CCO,,[Na+].[OH-],,test
US20150018332A1,O=C(/C=C\I)N1CC(F)(F)C1.O=C1CC(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CN1>>O=C1CC(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CN1/C=C/C(=O)N1CC(F)(F)C1,,CN(C)C=O,,O,[H-].[Na+],test
US06608059B1,Clc1cccc(Cl)c1CBr.Oc1ccc2[nH]ccc2c1>>Clc1cccc(Cl)c1COc1ccc2[nH]ccc2c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020120011A1,FC(F)(F)C1CO1.O=[N+]([O-])c1cccc(NCc2cccc(OC(F)(F)C(F)F)c2)c1>>O=[N+]([O-])c1cccc(N(Cc2cccc(OC(F)(F)C(F)F)c2)CC(O)C(F)(F)F)c1,,CC#N,,O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3],,test
US04847256,N#Cc1cnn2cccnc12>>N#Cc1cnn2c1NCCC2,,CO,,[BH4-].[Na+],,test
US20130041007A1,CI.Cc1ccc(S(=O)(=O)n2c3c(c4cc(Cl)c(Cl)cc42)CCCC3=O)cc1>>Cc1ccc(S(=O)(=O)n2c3c(c4cc(Cl)c(Cl)cc42)CCC(C)C3=O)cc1,,C1CCOC1,,[Cl-].[NH4+],C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20120225888A1,COC(=O)Cc1c(C)nc2c(-c3ccccc3)cnn2c1Cl.O=S(=O)(c1ccccc1)N1OC1c1ccccc1>>COC(=O)C(O)c1c(C)nc2c(-c3ccccc3)cnn2c1Cl,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20050153955A1,CN(C)CCN.[N-]=[N+]=NC(=O)CC1=CCNC(=O)c2[nH]c3ccc(F)cc3c21>>CN(C)CCNC(=O)C=C1CCNC(=O)c2[nH]c3ccc(F)cc3c21,,Cc1ccccc1,,,,test
US05391494,CC(=O)Cl.CCC(O)CO.O.c1ccncc1>>CCC(COC(C)=O)OC(C)=O,,Cc1ccccc1,,,,test
US20160060273A1,CC(C)(C)OC(=O)N1CC2(CC(Br)=NO2)C1.CCOC(=O)C1(CC)CCNCC1>>CCOC(=O)C1(CC)CCN(C2=NOC3(C2)CN(C(=O)OC(C)(C)C)C3)CC1,,O,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20040152712A1,CCOc1ncc(S(=O)(=O)N2CCN(CC)CC2)cc1-c1nc2c(CC)n(-c3ccc([N+](=O)[O-])cc3)nc2c(=O)[nH]1>>CCOc1ncc(S(=O)(=O)N2CCN(CC)CC2)cc1-c1nc2c(CC)n(-c3ccc(N)cc3)nc2c(=O)[nH]1,[Fe],CO,O,[Cl-].[NH4+],,test
US20050282858A1,C1=C(c2nccs2)CNC1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.c1csc(C2CCNC2)n1,O=[Pt]=O,,,CO,,test
US20140248378A1,CCOC(=O)C(F)(F)F.CCOC(=O)COC.N=C(N)SCc1ccccc1>>COc1c(C(F)(F)F)nc(SCc2ccccc2)[nH]c1=O,,C1CCOC1,CCO,CC(C)NC(C)C,[Li]CCCC,test
US20070049632A1,CC1(C)[C@@H]2CC[C@@]1(C)c1[nH]n(-c3ccc(Cl)cc3)c(=O)c12.COS(=O)(=O)OC>>Cn1c2c(c(=O)n1-c1ccc(Cl)cc1)[C@H]1CC[C@]2(C)C1(C)C,,[Na+],[OH-],,,test
US20090209588A1,Brc1cc(Br)nc(Br)c1.CCOC(=O)COc1ccc(S)cc1C>>CCOC(=O)COc1ccc(Sc2cc(Br)nc(Br)c2)cc1C,,CN1CCCC1=O,O,CCN(CC)CC,ClCCl,test
US20150284368A1,Cc1nc(Cl)cc(N2CC(c3nc4ccccc4n3C)C2)n1.NN>>Cc1nc(NN)cc(N2CC(c3nc4ccccc4n3C)C2)n1,,CC1CCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US20140194406A1,CCOC(=O)c1cc(-c2ccnc(N)n2)[nH]c1-c1cc(Cl)ccc1C.C[Si](C)(C)CCOCCl>>CCOC(=O)c1cc(-c2ccnc(N)n2)n(COCC[Si](C)(C)C)c1-c1cc(Cl)ccc1C,,C1CCOC1,,[H-].[Na+],,test
US06294566B1,CCOC=N.NCC(N)Cc1ccnc2ccccc12>>C1=NC(Cc2ccnc3ccccc23)CN1,,ClCCl,,Cl,N,test
US20050137224A1,COC(=O)[C@@H]1[C@@H]2C[C@@H](O)[C@@H](C2)N1C(=O)OC(C)(C)C.CS(=O)(=O)Cl>>COC(=O)[C@@H]1[C@@H]2C[C@@H](OS(C)(=O)=O)[C@@H](C2)N1C(=O)OC(C)(C)C,,c1ccncc1,,,,test
US20090076068A1,CCCCCCN=C=O.Cn1c(=O)[nH]c2ncccc21>>CCCCCCNC(=O)n1c(=O)n(C)c2cccnc21,,C1COCCO1,,,,test
US07786165B2,CC(C)Oc1cc(C=O)ccc1Cn1nc(-c2ccccc2)cc1-c1ccccc1.CCOC(=O)CCc1ccc(N)cc1F>>CCOC(=O)CCc1ccc(NCc2ccc(Cn3nc(-c4ccccc4)cc3-c3ccccc3)c(OC(C)C)c2)cc1F,,CCOC(C)=O,ClCCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05618811,Cc1ccccc1C1(O)CCC2(CC1)OCCO2>>Cc1ccccc1C1CCC(=O)CC1,[Pd],C1COCCO1,,Cl,[H][H],test
US20080312207A1,CC(C)Oc1cc(Oc2ccc(C(=O)O)cc2Cl)cc(C(=O)Nc2nccs2)c1.COCCN>>COCCNC(=O)c1ccc(Oc2cc(OC(C)C)cc(C(=O)Nc3nccs3)c2)c(Cl)c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110190255A1,CCOC(=O)C[C@H]1CCCN(CC(=O)c2ccc(C#N)cc2)C1>>CCOC(=O)C[C@H]1CCCN(CC(O)c2ccc(C#N)cc2)C1,,CO,,[BH4-].[Na+],,test
US20020052400A1,COc1ccc2ccc3c(c2c1)C=C(C(=O)O)CO3>>COc1ccc2ccc3c(c2c1)CC(C(=O)O)CO3,[Pd],CCO,CN(C)C=O,,,test
US20150125550A1,Cc1ccccc1.[Li]C(C)CC.c1cnc2c(c1)ccc1cccnc12>>CCC(C)c1ccc2ccc3ccc(C(C)CC)nc3c2n1,,Cc1ccccc1,,,,test
US06166038,N#CCC(=O)c1ccc(Cl)c(Cl)c1.NN>>Nc1cc(-c2ccc(Cl)c(Cl)c2)[nH]n1,,CCO,,O,,test
US20140303164A1,Nc1n[nH]c2c(Br)cccc12.O=C(O)c1ccccc1C(=O)O>>O=C1c2ccccc2C(=O)N1c1n[nH]c2c(Br)cccc12,,Cc1ccccc1,,,,test
US05232940,N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1SC(F)(F)F>>N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)cc1SC(F)(F)F,,C1CCOC1,,CC(C)(C)ON=O,,test
US20050203151A1,COC(=O)COc1cccc2c1ccn2Cc1sc(-c2ccc(C(F)(F)F)cc2)nc1C>>Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1Cn1ccc2c(OCC(=O)O)cccc21,,C1CCOC1,CO,[Li+].[OH-],,test
US20100234485A1,CCCC[Sn](=O)CCCC.O=C(c1ccccc1)C(O)(CO)c1ccccc1>>CCCC[Sn]1(CCCC)OCC(C(=O)c2ccccc2)(c2ccccc2)O1,,Cc1ccccc1,,,,test
US20100063013A1,C=C(C)OC.CC(C)(C)OC(=O)N[C@H](CO)CCC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N1[C@@H](CCC(=O)OCc2ccccc2)COC1(C)C,,ClCCl,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US05142048,CC(C)CC[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)N(C)C(=O)[C@H](Cc1ccccc1)OC(=O)N(C)CCC(=O)N1CCOCC1.Cl>>CC(C)CC[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)N(C)C(=O)[C@H](Cc1ccccc1)OC(=O)N(C)CCC(=O)N1CCOCC1.Cl,,C1COCCO1,CCO,,,test
US20040198711A1,C[C@]12CC[C@@H]3c4ccc(OCc5ccccc5)cc4CC[C@H]3[C@@H]1C=CC21OCCO1>>C[C@]12CC[C@@H]3c4ccc(OCc5ccccc5)cc4CC[C@H]3[C@@H]1C=CC2=O,,CC(C)=O,O,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20100016361A1,CC1CNCCC1OC(=O)C(C)(C)C.O=C([O-])C(O)(C(=O)c1ccccc1)C(O)(C(=O)[O-])C(=O)c1ccccc1>>C[C@H]1CNCC[C@@H]1OC(=O)C(C)(C)C.O=C(O)C(O)(C(=O)c1ccccc1)C(O)(C(=O)O)C(=O)c1ccccc1,,CCOC(C)=O,,,,test
US20120295905A1,CS(=O)(=O)c1ccc(-c2cnc(N)c(Br)c2)cc1.NC(=O)c1ccc(B(O)O)cc1>>CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3ccc(C(N)=O)cc3)c2)cc1,,C1COCCO1,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20140005213A1,CCOC(=O)C1(CF)CCNC1.O=C(Cl)OCc1ccccc1>>CCOC(=O)C1(CF)CCN(C(=O)OCc2ccccc2)C1,,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20160052898A1,COCCO.O=C(O)c1ccc(CBr)c([N+](=O)[O-])c1>>COCCOCc1ccc(C(=O)O)cc1[N+](=O)[O-],,O,,Cl,[H-].[Na+],test
US04558047,Nc1nc2nc[nH]c2c(=O)[nH]1.O=CC(CO)OC(C=O)n1cnc2c(=O)[nH]cnc21>>O=c1[nH]cnc2c1ncn2[C@@H]1O[C@H](CO)C(O)N(c2nc3nc[nH]c3c(=O)[nH]2)C1O,,CO,O,,,test
US04308276,CCOC(=O)C(Br)CBr.Oc1ccccc1S>>O=C(O)C1CSc2ccccc2O1,,CC(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20050026916A1,CI.Cc1ccc([C@@H]2NC(=S)N[C@@H]2c2ccc(C)cc2)cc1>>CSC1=N[C@@H](c2ccc(C)cc2)[C@@H](c2ccc(C)cc2)N1.I,,CCO,,,,test
US20060229338A1,CSc1ccc(-c2cc(Cl)cnc2OCc2ccccc2)cc1>>CSc1ccc(-c2cc(Cl)cnc2O)cc1,,O=C(O)C(F)(F)F,,,,test
US20130184459A1,N#Cc1cccc(C(=O)c2ccc3ccccc3c2[N+](=O)[O-])c1>>N#Cc1cccc(C(=O)c2ccc3ccccc3c2N)c1,[Fe],CC(=O)O,,CCO,O,test
US20040181028A1,N#Cc1ccc([N+](=O)[O-])cc1C#N>>N#Cc1ccccc1C#N,,Cc1ccccc1,O,Cl,O=C([O-])[O-].[K+].[K+],test
US05880147,CCCCCC(CC(=O)Nc1cc(C(=O)O)ccc1C(C)(C)C)c1ccc(OC)cc1OC.NC(=O)c1ccncc1>>CCCCCC(CC(=O)Nc1cc(C(=O)NC(=O)c2ccncc2)ccc1C(C)(C)C)c1ccc(OC)cc1OC,,CCOC(C)=O,,,,test
US20140114068A1,CC(C)c1ccc2c(c1)OC1(N)c3ccccc3C(=O)C21O.O=C(O)c1cc(=O)[nH]c(=O)[nH]1>>CC(C)c1ccc2c(c1)OC1(O)c3ccccc3C(=O)C21NC(=O)c1cc(=O)[nH]c(=O)[nH]1,,CN(C)C=O,ClCCl,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20040132727A1,CCOc1ccccc1C(C)O.COc1cc2nccc(Oc3ccc(N)c(C)c3C)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCOc1ccccc1C(C)OC(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)c(C)c1C,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20060188938A1,CCOC(=O)CC(C)=O.COC(=O)/C=C(/C)N.O=Cc1ccccc1Br>>CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1ccccc1Br,,CCO,CCOC(C)=O,CC(=O)O,,test
US20020106697A1,O=C1OC(=O)c2ccccc21.Oc1ccc(Cl)c(O)c1>>O=C(O)c1ccccc1C(=O)c1cc(Cl)c(O)cc1O,,O=[N+]([O-])c1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20130096174A1,C[C@@H]1CC(C)(C)c2cccc(N)c21.Cn1cc(C(=O)Cl)c(C(F)F)n1>>C[C@@H]1CC(C)(C)c2cccc(NC(=O)c3cn(C)nc3C(F)F)c21,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20080176898A1,CCOC(=O)c1ccc(OCCCc2ccc(OCCCC3CCCCC3)cc2)c(CC(=O)NCCCC(=O)OC)c1>>O=C(O)CCCNC(=O)Cc1cc(C(=O)O)ccc1OCCCc1ccc(OCCCC2CCCCC2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US05998436,CCOC(=O)C(=CNc1nc(NC(C)(C)C)c(F)cc1F)C(=O)c1cc(F)c(F)c(C)c1F>>CCOC(=O)c1cn(-c2nc(NC(C)(C)C)c(F)cc2F)c2c(C)c(F)c(F)cc2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040110807A1,CC(C)(C)c1ccc(-c2nc(CCl)cs2)cc1.CCOC(=O)C(Cc1ccc(O)c(F)c1)OCC>>CCOC(=O)C(Cc1ccc(OCc2csc(-c3ccc(C(C)(C)C)cc3)n2)c(F)c1)OCC,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160158207A1,CC1CCN(c2nn(C3CCOCC3)c3c2CN(C(=O)OC(C)(C)C)CC3)c2cc(C(F)F)c(-c3cnn(C)c3)cc21>>CC1CCN(c2nn(C3CCOCC3)c3c2CNCC3)c2cc(C(F)F)c(-c3cnn(C)c3)cc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110178056A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N#Cc1cccc2c1CCC[C@@H]2N=[N+]=[N-]>>CC(C)(C)OC(=O)N[C@H]1CCCc2c(C#N)cccc21,[Pd],CO,,CCN(CC)CC,,test
US20160194302A1,CCOC(=O)CCn1ccnc1CCC(=O)O.CN(C)[C@H]1CCCNC1>>CCOC(=O)CCn1ccnc1CCC(=O)N1CCC[C@H](N(C)C)C1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04971982,CC1(C)CC(c2ccccn2)c2cc(C(=O)c3ccc([N+](=O)[O-])cc3)ccc2O1.O=C(OO)c1cccc(Cl)c1>>CC1(C)CC(c2cccc[n+]2[O-])c2cc(C(=O)c3ccc([N+](=O)[O-])cc3)ccc2O1,,ClCCl,,,,test
US20050209284A1,CC(C)(O)CN.O=[N+]([O-])c1ccccc1F>>CC(C)(O)CNc1ccccc1[N+](=O)[O-],,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20120302541A1,CCN(CC)C(=O)CCc1ccc(NC[C@@H]2CCCN2C(=O)OC(C)(C)C)c(Oc2ccc(OC)cc2)c1>>CCN(CC)C(=O)CCc1ccc(NC[C@@H]2CCCN2)c(Oc2ccc(OC)cc2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140296200A1,Cc1cc(Cl)ncc1Br.NN>>Cc1cc(NN)ncc1Br,,CCO,,O,,test
US04076729,Cc1oc2ccccc2c(=O)c1[N+](=O)[O-]>>Cc1oc2ccccc2c(=O)c1N,[Pd],CCO,,,,test
US20160096834A1,CC(C)(C)c1nc(C(=O)NCc2ccc(-c3ccnc4[nH]c(-c5cnn(CCN6C(=O)c7ccccc7C6=O)c5)nc34)cc2F)no1>>CC(C)(C)c1nc(C(=O)NCc2ccc(-c3ccnc4[nH]c(-c5cnn(CCN)c5)nc34)cc2F)no1,,CCO,O,NN,,test
US04147793,BrBr.CC(CC(=O)c1ccccc1)c1ccccc1>>CC(c1ccccc1)C(Br)C(=O)c1ccccc1,,CCOCC,,,,test
US20130085164A1,CCC(O)c1cnc(-c2cccc(F)c2)s1.O=C(n1ccnc1)n1ccnc1>>CCC(c1cnc(-c2cccc(F)c2)s1)n1ccnc1,,CC#N,,,,test
US20090023917A1,CS(=O)(=O)Oc1c(Br)ccc2cc(OCc3ccccc3)ccc12.OB(O)c1ccc(F)cc1>>CS(=O)(=O)Oc1c(-c2ccc(F)cc2)ccc2cc(OCc3ccccc3)ccc12,,Cc1ccccc1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US05686482,COc1cc(C)ccc1C(=O)O.O=[N+]([O-])O>>COc1cc(C)c([N+](=O)[O-])cc1C(=O)O,,O=S(=O)(O)O,,,,test
US20080045528A1,COc1ccc2nc(NCC3CCCCC3)sc2c1>>Oc1ccc2nc(NCC3CCCCC3)sc2c1,,ClCCl,,BrB(Br)Br,,test
US20140005146A1,COC(=O)[C@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C>>COC(=O)[C@H]1CC(=O)CN1C(=O)OC(C)(C)C,,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20040138211A1,COC(=O)C(Cc1ccc(OCCOc2ccc3ncccc3c2)cc1)C(=O)OC>>COC(=O)C(Cc1ccc(OCCOc2ccc3ncccc3c2)cc1)C(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20060223797A1,CC(C)(C)C(=O)Nc1nc(Cl)c2c(I)c[nH]c2n1.COc1c(C)c[n+]([O-])c(CCl)c1C>>COc1c(C)c[n+]([O-])c(Cn2cc(I)c3c(Cl)nc(NC(=O)C(C)(C)C)nc32)c1C,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20020098152A1,CC(C)(C)OC(=O)CN1CCNCCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1.CCCCCCCCCCCCCCCCCCBr>>CCCCCCCCCCCCCCCCCCN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1,,CC#N,,,,test
US20160002225A1,CC(C)(C)OC(=O)N1CCC[C@@H](N)C1.CCOC(=O)c1cccc(Nc2ccnc3c2c(Br)nn3Cc2ccc(OC)cc2)c1>>CCOC(=O)c1cccc(Nc2ccnc3c2c(N[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)nn3Cc2ccc(OC)cc2)c1,I[Cu]I,CS(C)=O,O,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US04839379,CC(=O)Nc1ccc(C23CC2C(=O)NC3=O)cc1.CI>>CC(=O)Nc1ccc(C23CC2C(=O)N(C)C3=O)cc1,,CN(C)C=O,CN(C)C=O,[H-].[Na+],,test
US20150266867A1,CC(C)(C)OC(=O)N=C(NCc1cn(C[C@@H]2[C@H](NC(=O)/C(=N\OC(C)(C)C(=O)O)c3csc(N)n3)C(=O)N2S(=O)(=O)O)nn1)NC(=O)OC(C)(C)C>>CC(C)(O/N=C(\C(=O)N[C@@H]1C(=O)N(S(=O)(=O)O)[C@@H]1Cn1cc(CNC(=N)N)nn1)c1csc(N)n1)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110130415A1,CI.COc1cc(-n2nn[nH]c2=O)cc([N+](=O)[O-])c1>>COc1cc(-n2nnn(C)c2=O)cc([N+](=O)[O-])c1,,ClCCl,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20040152690A1,BrBr.C[C@@H]1CN(c2ncccc2C(F)(F)F)CCN1C(=O)OC(C)(C)C>>C[C@@H]1CN(c2ncc(Br)cc2C(F)(F)F)CCN1C(=O)OC(C)(C)C,,ClCCl,,,,test
US04792561,O=C1CCc2cc(C(O)(Cn3ccnc3)c3ccccc3)ccc2N1>>O=C1CCc2cc(C(=Cn3ccnc3)c3ccccc3)ccc2N1,,O=CO,,,,test
US06303593B1,O=C(O)c1cccc2cc[nH]c12.c1ccc(C2CCN(CC3CNCC3c3ccsc3)CC2)cc1>>O=C(c1cccc2cc[nH]c12)N1CC(CN2CCC(c3ccccc3)CC2)C(c2ccsc2)C1,,ClCCl,,CCN(CC)CC,O=C1OCCN1P(=O)(Cl)N1CCOC1=O,test
US20160175284A1,CC1=C(c2cc(C#C[Si](C)(C)C)cc(OC3CCCCO3)c2)C(c2ccc(OC[C@H](C)N3CC[C@@H](CF)C3)cc2)Oc2ccc(OC3CCCCO3)cc21>>C#Cc1cc(OC2CCCCO2)cc(C2=C(C)c3cc(OC4CCCCO4)ccc3OC2c2ccc(OC[C@H](C)N3CC[C@@H](CF)C3)cc2)c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04230713,CN1CC(=O)N=C1N.O=C=Nc1ccc(Br)s1>>CN1CC(=O)NC1=NC(=O)Nc1ccc(Br)s1,,CN(C)C=O,Cc1ccccc1,O,,test
US04746655,C1CCOC1.CC(=O)OC1(CN)CCN(C)CC1.CO.NC=O>>CNCC1(O)CCN(C)CC1.O=C(O)C(=O)O,,C1CCOC1,,N,,test
US20100048636A1,CCOC(=O)COC(c1cccc(F)c1F)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CCC[C@@H](C(OCCO)c2cccc(F)c2F)C1,,CO,,[BH4-].[Na+],,test
US20130109701A1,COC(=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1>>O=C(O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1,,C1CCOC1,,[Li+].[OH-],,test
US20120077793A1,C[C@@H](c1ccc(OC(=O)OC(C)(C)C)cc1F)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC(F)(F)C1>>C[C@@H](c1ccc(O)cc1F)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC(F)(F)C1,,ClCCl,,C1CCNCC1,,test
US04649146,Cc1ccn2cc(-c3sc(N(C)C=O)nc3C)nc2c1>>CNc1nc(C)c(-c2cn3ccc(C)cc3n2)s1,,CCO,,Cl,,test
US20060106022A1,Nc1ncc(Br)nc1NCc1cccc([N+](=O)[O-])c1.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2ncc(Br)nc2n1Cc1cccc([N+](=O)[O-])c1,,C1CCOC1,,,,test
US20120309739A1,COc1nc(N2CCN(C(C)=O)CC2)nc2oc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)c12>>COc1nc(N2CCN(C(C)=O)CC2)nc2oc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100240669A1,COC(=O)c1ccc(Nc2ccc(C#N)nc2)c(C(F)(F)F)c1>>COC(=O)c1ccc(Nc2ccc(CN)nc2)c(C(F)(F)F)c1,[Ni],N,,,,test
US20040019218A1,CC[C@@H](C=O)NC(=O)OC(C)(C)C.c1cnc2ncoc2c1>>CC(NC(=O)OC(C)(C)C)[C@H](O)c1nc2ncccc2o1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US04668682,CN(C)CCCl.COc1ccc(OC)c(Cc2nc3ccc(C)cc3c(=O)[nH]2)c1>>COc1ccc(OC)c(Cc2nc3ccc(C)cc3c(=O)n2CCN(C)C)c1,,C1COCCO1,,O,[H-].[Na+],test
US04607128,CC=COc1ccc(C(F)(F)F)cc1>>Oc1ccc(C(F)(F)F)cc1,,CO,,O=S(=O)(O)O,,test
US20100298321A1,COc1ccc(CNCc2ccc(OC)cc2OC)c(OC)c1.O=S(=O)(Cl)c1ccc(F)c(Cl)c1>>COc1ccc(CN(Cc2ccc(OC)cc2OC)S(=O)(=O)c2ccc(F)c(Cl)c2)c(OC)c1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US05468721,COC(=O)c1ccccc1OCc1nc(OC)cc(OC)n1>>COc1cc(OC)nc(COc2ccccc2C(=O)O)n1,,CCO,O,[K+].[OH-],,test
US04451469,CCCC(=O)CC(=O)CCC.N#CCC(N)=O>>CCCc1cc(CCC)c(C#N)c(=O)[nH]1,,CC(=O)O,O,CO,C[O-].[Na+],test
US04410526,COC(=O)CCCCCCC(Br)C(=O)OC.[N-]=[N+]=[N-]>>COC(=O)CCCCCCC(N=[N+]=[N-])C(=O)OC,,CC#N,,,,test
US20100048564A1,CC(C)(C)OC(=O)NCc1cc(Cl)ccc1[N+](=O)[O-].COc1ccc(O)cc1>>COc1ccc(Oc2ccc([N+](=O)[O-])c(CNC(=O)OC(C)(C)C)c2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20080261989A1,CC(=O)c1cc(N)ccc1Cl.COc1cc(OC)cc(C(=O)Cl)c1>>COc1cc(OC)cc(C(=O)Nc2ccc(Cl)c(C(C)=O)c2)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US06310070B1,CCC(=O)OC(=O)CC.NC(=O)c1c(N)ncn1Cc1ccccc1>>CCC(=O)Nc1ncn(Cc2ccccc2)c1C(N)=O,,CN(C)C=O,,CCN(CC)CC,,test
US20090181928A1,C[Si](C)(C)CCN1C(=O)CN(c2ccc(Cc3ccccc3C#N)cc2OCc2ccccc2)S1(=O)=O>>N#Cc1ccccc1Cc1ccc(N2CC(=O)NS2(=O)=O)c(OCc2ccccc2)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04072696,CC(=O)Nc1cc(S(=O)c2ccccc2)ccc1N.COC(=O)N=C=S>>COC(=O)NC(=S)Nc1ccc(S(=O)c2ccccc2)cc1NC(C)=O,,CC(C)=O,,,,test
US20130131018A1,CCOc1cccc(CNCC(OCC)OCC)c1O.COc1cc(C=O)cc(OC)c1OCC(C)(C)C.Cl>>CCOc1ccc2c(Cc3cc(OC)c(OCC(C)(C)C)c(OC)c3)cncc2c1O.Cl,,CCO,,CO,,test
US04526983,CC(C)[C@H](C(=O)SC[C@](O)(Cn1ccnc1)c1ccc(Cl)cc1Cl)c1ccc(Cl)cc1.CCCCBr>>CCCCSC[C@](O)(Cn1ccnc1)c1ccc(Cl)cc1Cl.Cl,,CO,,[K+].[OH-],,test
US20090137557A1,Cn1ncc(C(=O)NCCc2cccc(F)c2)c1N.O=C(Cl)c1ccccc1OCc1ccccc1>>Cn1ncc(C(=O)NCCc2cccc(F)c2)c1NC(=O)c1ccccc1OCc1ccccc1,,C1CCOC1,c1ccncc1,,,test
US04127661,C1CNCCN1.ClCCCSc1ccccc1>>c1ccc(SCCCN2CCNCC2)cc1,,CCC(C)=O,,[I-].[Na+],,test
US05491145,CC(=O)OCCCS(=O)(=O)Cl.CN>>CNS(=O)(=O)CCCOC(C)=O,,ClCCl,,,,test
US05025031,NS(=O)(=O)Cl.Oc1ccc(-n2cncn2)cc1>>Cl.NS(=O)(=O)Oc1ccc(-n2cncn2)cc1,,ClCCl,,CCN(CC)CC,,test
US20160068559A1,CC1(C)O[C@@H]2[C@H](O1)[C@@H](CNCCCNC(=O)Nc1ccc(C(C)(C)C)cc1)O[C@H]2n1cnc2c(N)ncnc21.CC=O>>CCN(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21,,C1CCOC1,ClCCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20040049008A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCCO.O=C1CCC(=O)O1>>CC(C)(C)OC(=O)NCCCOC(=O)CCC(=O)O,,CO,,CCN(CC)CC,,test
US20070066639A1,Nc1nc2c(c3c1ncn3CCCCO)CCCC2.O=C1c2ccccc2C(=O)N1O>>Nc1nc2c(c3c1ncn3CCCCON1C(=O)c3ccccc3C1=O)CCCC2,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04904658,BrCc1ccccc1.O=c1[nH]c(=O)n2c3c1ncn3C(c1cccc(C(F)(F)F)c1)=CC2>>O=c1c2ncn3c2n(c(=O)n1Cc1ccccc1)CC=C3c1cccc(C(F)(F)F)c1,,CN(C)C=O,,[H-].[Na+],,test
US20090270402A1,CCN=C=S.NNc1ccc(-c2c(-c3ccc(F)cc3F)nc3n2CCC3)nn1>>CCNc1nnc2ccc(-c3c(-c4ccc(F)cc4F)nc4n3CCC4)nn12,CN(C)c1ccncc1,CCO,,,,test
US05246927,CC(=O)N1CCNCC1.CC1CCN(c2cc3nc(C(C)(C)C)sc3cc2N=C=S)CC1>>CC(=O)N1CCN(C(=S)Nc2cc3sc(C(C)(C)C)nc3cc2N2CCC(C)CC2)CC1,,ClC(Cl)Cl,,,,test
US20100173955A1,COC(=O)c1ccc(Oc2ccc(CC(=O)OC(C)(C)C)cc2CN)cc1.CS(=O)(=O)Cl>>COC(=O)c1ccc(Oc2ccc(CC(=O)OC(C)(C)C)cc2CNS(C)(=O)=O)cc1,,Cl,ClCCl,c1ccncc1,,test
US20100035869A1,CC(C)C[C@H](NC(=O)OCc1ccccc1)C1CC1CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>CC(C)C[C@H](N)C1CC1CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,CCOC(C)=O,CO,,,test
US20020193382A1,COC(=O)[C@@H]1CC[C@@H](CN2C=CN(C(=O)OCc3ccccc3)CC2=O)CC1>>COC(=O)[C@@H]1CC[C@@H](CN2CCNCC2=O)CC1,[Pd],CO,,,,test
US20160184318A1,CC(=O)NN.CCOC(C)=O.O=C(O)Cc1cc(Cl)ccc1Br>>Cc1nnc(Cc2cc(Cl)ccc2/C=C/C(=O)O)o1,,CCOC(C)=O,O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US20120142717A1,COC(=O)CCc1cnc(OC)nc1.COC=O>>COC(=O)C(=CO)Cc1cnc(OC)nc1,,COCCOC,,[H-].[Na+],,test
US20050209290A1,C=CCOc1ccc(CCl)c(F)c1.OCCn1ccnn1>>C=CCOc1ccc(COCCn2ccnn2)c(F)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20120157439A1,Cc1ccc(S(=O)(=O)Cl)cc1.N#C/C(=N\O)C(N)=O>>Cc1ccc(S(=O)(=O)O/N=C(\C#N)C(N)=O)cc1,,c1ccncc1,,,,test
US20100130495A1,CC(=O)OC(C)=O.COc1cccc(Cc2nc(Nc3ccc(-n4cnc(C)c4)c(OC)c3)nc3c2CNCC3)c1>>COc1cccc(Cc2nc(Nc3ccc(-n4cnc(C)c4)c(OC)c3)nc3c2CN(C(C)=O)CC3)c1,,ClCCl,,,,test
US20130023541A1,CC(C)(C)[Si](C)(C)OCc1ccc(C=O)nc1.CC(C)OC(=O)c1cccnc1N1CCNCC1>>CC(C)OC(=O)c1cccnc1N1CCN(Cc2ccc(CO[Si](C)(C)C(C)(C)C)cn2)CC1,,C1CCOC1,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100087475A1,COc1cc(C=O)ccc1O.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1cc(C=O)ccc1OS(=O)(=O)c1ccc(C)cc1,,CC(C)=O,ClCCl,O,O=C([O-])[O-].[K+].[K+],test
US20130012518A1,Cc1ccc(N)cc1N1CCc2nc(Nc3ccc(C(=O)N4CCN(C)CC4)cc3)ncc2C1=O.O=C(O)c1cccc(C(F)(F)F)c1>>Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1N1CCc2nc(Nc3ccc(C(=O)N4CCN(C)CC4)cc3)ncc2C1=O,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030055265A1,CCOC(=O)/C(=C/c1ccc(OCc2ccccc2)cc1C)OCC>>CCOC(=O)C(Cc1ccc(O)cc1C)OCC,[Pd],CCO,,,,test
US05550147,COc1ccc(-n2nc(C(F)F)cc2-c2ccc(SC)cc2)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(-n2nc(C(F)F)cc2-c2ccc(S(C)=O)cc2)cc1,,ClCCl,,,,test
US20150210720A1,CC(=O)C=C1CCOCC1.COC(=O)CC(=O)OC>>COC(=O)C1C(=O)CC(=O)CC12CCOCC2,,CO,,C[O-].[Na+],,test
US20110212918A1,BrB(Br)Br.COc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(CO)c1>>O=S(=O)(Nc1ccc2c(c1)B(O)OC2)c1ccc(O)cc1CBr,,ClCCl,,,,test
US05550117,CCN(C(C)C)C(C)C.Cc1ccnc2c1NC(=O)c1cccnc1N2C1CC1>>Cc1ccnc2c1N=C(C#N)c1cccnc1N2C1CC1,,ClCCl,,,,test
US06297258B1,CC1CCC(C)N1.COc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CCBr>>COc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CCN1C(C)CCC1C,,CN(C)C=O,,,,test
US20100035865A1,CCOC(=O)C1=C(O)COCC1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)C1=C(OS(=O)(=O)C(F)(F)F)COCC1,,CCOCC,,[H-].[Na+],,test
US20090105244A1,Cc1c(Cl)c(S(C)=O)nc2sc(C(=O)NC3CC3)c(N)c12.OCCCO>>Cc1c(Cl)c(OCCCO)nc2sc(C(=O)NC3CC3)c(N)c12,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05847231,COC(=O)c1cccc(OC(=O)C(=O)Oc2cccc(C(=O)OC)c2)c1.O=[N+]([O-])O>>COC(=O)c1cc(O)ccc1[N+](=O)[O-],,CO,,O=S(=O)(O)O,,test
US20140256546A1,COc1c(-c2ccc(C(F)(F)F)cc2S(C)(=O)=O)c(N)nn(C)c1=O.O=N[O-]>>COc1c(-c2ccc(C(F)(F)F)cc2S(C)(=O)=O)c(=O)[nH]n(C)c1=O,,O,O=S(=O)(O)O,CC(=O)O,,test
US20150284368A1,Cn1c(C2CN(C(=O)OCc3ccccc3)C2)nc2ccccc21>>Cn1c(C2CNC2)nc2ccccc21,[Pd],CO,,[H][H],,test
US20080280875A1,CC(O)c1ccccn1.Cn1ccc(NC(=O)c2cc(O)c3c(c2)OC(C)(C)C3)n1>>CC(Oc1cc(C(=O)Nc2ccn(C)n2)cc2c1CC(C)(C)O2)c1ccccn1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030144507A1,Nc1ccc2cnccc2c1.O=C(OO)c1cccc(Cl)c1.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=S(=O)(Nc1ccc2c[n+]([O-])ccc2c1)c1ccc(Cl)cc1,,ClC(Cl)Cl,,,,test
US20040224961A1,COc1nc2nc(SCc3ccccc3F)nc(N[C@H](C)CO)c2s1>>C[C@H](CO)Nc1nc(SCc2ccccc2F)nc2[nH]c(=O)sc12,,C1COCCO1,,Cl,O,test
US06166006,CI.Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CN(C)C4CCOCC4)cc2)CCC3)cc1>>Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(C[N+](C)(C)C4CCOCC4)cc2)CCC3)cc1.[I-],,CN(C)C=O,,,,test
US20140093505A1,Brc1ccc(-n2cccn2)nc1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(c2ccc(-n3cccn3)nc2)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20060105997A1,CCS(=O)(=O)CCN1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1.CI>>CCS(=O)(=O)C(C)CN1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20060257987A1,CCc1ccc(O)c(-c2cscn2)c1.CN(C)C=O.COC(=O)CCc1ccc(OCC[C@H](C)OS(C)(=O)=O)cc1>>CCc1ccc(O[C@@H](C)CCOc2ccc(CCC(=O)OC)c(C)c2)c(-c2cscn2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070010573A1,NC(=O)[C@@H](N)Cc1ccc(I)cc1.O=S1(=O)CCCO1>>N[C@@H](Cc1ccc(I)cc1)C(=O)NCCCS(=O)(=O)O,CN(C)C=O,CCC(C)=O,,,,test
US04526896,CN(C)CCCl.Cl.O=[N+]([O-])c1oc2cc(O)ccc2c1-c1ccccc1>>CN(C)CCOc1ccc2c(-c3ccccc3)c([N+](=O)[O-])oc2c1.Cl,,COCCOC,,[H-].[Na+],,test
US20090062332A1,CC(C)(C)OC(=O)NC(CC1CCCCC1)C(=O)O.CI>>COC(=O)C(CC1CCCCC1)NC(=O)OC(C)(C)C,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US05292726,Clc1cccc(Nc2ccccc2)c1.O=C(Cl)Cl>>O=C(Cl)N(c1ccccc1)c1cccc(Cl)c1,,Cc1ccccc1,,,,test
US20090221547A1,Cc1cccc(-c2ccc(O)cc2C(F)(F)F)c1.OCc1ccc(-c2nc(C(F)(F)F)c[nH]2)cc1>>Cc1cccc(-c2ccc(OCc3ccc(-c4nc(C(F)(F)F)c[nH]4)cc3)cc2C(F)(F)F)c1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100056550A1,CC(C)(C)OC(=O)N1CC(=O)C(C#N)C1.NN>>CC(C)(C)OC(=O)N1Cc2n[nH]c(N)c2C1,,CCO,,Cl,O=C([O-])O.[Na+],test
US04877793,CCOC(=O)c1cnc2cc(Cl)sc2c1O.CI>>CCOC(=O)c1cn(C)c2cc(Cl)sc2c1=O,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20110250135A1,Cc1ccc(S(=O)(=O)OCCOS(=O)(=O)c2ccc(C)cc2)cc1.O=C(NCC(=O)N1CCN(c2ccc(OCc3ccccc3)cc2)CC1)c1cccc(O)c1>>Cc1ccc(S(=O)(=O)OCCOc2cccc(C(=O)NCC(=O)N3CCN(c4ccc(OCc5ccccc5)cc4)CC3)c2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06171866B2,CCOc1ccc(OCC)c(CCN)c1.O=[N+]([O-])O>>CCOc1cc([N+](=O)[O-])c(OCC)cc1CCN,,O,,Cl,[Na+].[OH-],test
US20160030395A1,Cc1noc(C)c1-c1ccc2c(c1)C(O)(c1ccccc1)C(=O)N2.O=S(Cl)Cl>>Cc1noc(C)c1-c1ccc2c(c1)C(Cl)(c1ccccc1)C(=O)N2,,C1CCOC1,,c1ccncc1,,test
US20040198728A1,COc1ccc(Cl)cc1-c1cc(NC(=O)OC(C)(C)C)nc(NC(=O)OC(C)(C)C)c1.O=C(O)C(F)(F)F>>COc1ccc(Cl)cc1-c1cc(N)nc(N)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20030027771A1,CC(C)(C)OC(=O)[C@@H](N)Cc1ccc(O)cc1.O=C(O)[C@@H]1CCC(=O)N1Cc1ccccc1>>CC(C)(C)OC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCC(=O)N1Cc1ccccc1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US04307230,CC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)C(N)C2SC1.CON=C(C(=O)OC(=O)C(=NOC)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>CON=C(C(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(C)CSC12)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,ClCCl,,,,test
US20090054437A1,CCOC(=O)CC(=O)c1ccc[n+]([O-])c1C(F)(F)F.COc1cc(C(=O)CBr)cc([N+](=O)[O-])c1OC>>CCOC(=O)c1c(-c2cc(OC)c(OC)c([N+](=O)[O-])c2)coc1-c1ccc[n+]([O-])c1C(F)(F)F,,c1ccncc1,,Cl,,test
US20100022513A1,CC1(C)N=C(c2ccc(F)cc2)OC1=O.Nc1nc(-c2ccc(F)cc2)n(Cc2ccccc2)n1>>CC(C)(NC(=O)c1ccc(F)cc1)C(=O)Nc1nc(-c2ccc(F)cc2)n(Cc2ccccc2)n1,,CCOC(C)=O,,CN1CCCC1=O,,test
US20110009454A1,C#CCBr.Nc1ncccc1C(=O)NCc1ccc(O)cc1>>C#CCOc1ccc(CNC(=O)c2cccnc2N)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100010024A1,CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(CC(=O)OC(C)(C)C)[C@@H]1c1ccc(C#N)cc1>>CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(CC(=O)O)[C@@H]1c1ccc(C#N)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060223826A1,CCOC(=O)c1ccc2c(c1)NC(=O)CS2>>O=C1CSc2ccc(C(=O)O)cc2N1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20070117839A1,CCOC(=O)[C@H]1CCC(=O)N1C(=O)OC(C)(C)C.Fc1cccc([Mg]Br)c1>>CCOC(=O)[C@@H](CCC(=O)c1cccc(F)c1)NC(=O)OC(C)(C)C,,C1CCOC1,,O,,test
US20070167622A1,CCOC(=O)c1csc(-c2ccccc2CO)n1>>O=C(O)c1csc(-c2ccccc2CO)n1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20100113444A1,CC(C)c1ccc(CCl)cc1.CCOC(=O)CNC(=O)c1c(O)n(C2CCCCC2)c(=O)[nH]c1=O>>CC(C)c1ccc(Cn2c(=O)c(C(=O)NCC(=O)O)c(O)n(C3CCCCC3)c2=O)cc1,,CC(=O)N(C)C,,Cl,O=C([O-])[O-].[K+].[K+],test
US05344843,BrCCCc1ccc2ccccc2c1.COC(=O)C(=O)c1ccc(O)cc1>>COC(=O)C(=O)c1ccc(OCCCc2ccc3ccccc3c2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20120058989A1,CCOC(=O)c1cn(C2CC2)c2c(C#CC[C@@H]3[C@H](O)CCN3C(=O)OC(C)(C)C)c(F)c(F)cc2c1=O>>CCOC(=O)c1cn(C2CC2)c2c(/C=C\C[C@@H]3[C@H](O)CCN3C(=O)OC(C)(C)C)c(F)c(F)cc2c1=O,,CCO,,,,test
US20110034696A1,CC(NC(=O)c1cc(Cl)ccc1NC(=O)C1CC(O)=NN1c1ncccc1Cl)C1CC1.O=S(=O)(Cl)c1cccnc1>>CC(NC(=O)c1cc(Cl)ccc1NC(=O)C1CC(OS(=O)(=O)c2cccnc2)=NN1c1ncccc1Cl)C1CC1,CN(C)c1ccncc1,C1CCOC1,CCOC(C)=O,CCN(CC)CC,O,test
US20060177943A1,CC(C)(C)OC(=O)COCCOCCOCCOCCOCCOc1cc(OCCOCCOCCOCCOCCNC(=O)OCC2c3ccccc3-c3ccccc32)cc(OCCOCCOCCOCCOCCNC(=O)OCC2c3ccccc3-c3ccccc32)c1>>O=C(O)COCCOCCOCCOCCOCCOc1cc(OCCOCCOCCOCCOCCNC(=O)OCC2c3ccccc3-c3ccccc32)cc(OCCOCCOCCOCCOCCNC(=O)OCC2c3ccccc3-c3ccccc32)c1,,Cc1ccccc1,,,,test
US20050245562A1,O=P(Cl)(Cl)Cl.[O-][n+]1cc2ncn(-c3ccccc3Cl)c2c2cc(Cl)ccc21>>Clc1ccc2nc(Cl)c3ncn(-c4ccccc4Cl)c3c2c1,,CCOC(C)=O,Cc1ccccc1,CN(C)C=O,O,test
US20080004274A1,CCCCCCCN1C(=O)C(=O)c2cc(SCCc3ccc(C(=O)OCC)cc3)ccc21>>CCCCCCCN1C(=O)C(=O)c2cc(SCCc3ccc(C(=O)O)cc3)ccc21,,CO,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20050288287A1,CC(C)(C)c1cc(O)c(I)cc1Cl.CCI>>CCOc1cc(C(C)(C)C)c(Cl)cc1I,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100160309A1,CC(C)[C@@H](Nc1nc2ccnc(Cl)c2c2cc(Br)ccc12)C(F)(F)F.CCOC(C)=O>>CC(C)[C@@H](Nc1nc2cc[nH]c(=O)c2c2cc(Br)ccc12)C(F)(F)F,,CCOC(C)=O,Cl,C1CCOC1,,test
US07402606B2,CCCC[C@H](NC(=O)OC1C(=O)N(C(=O)OCc2ccccc2)CC1(C)C)C(O)C(=O)N[C@H](C)c1ccccc1>>CCCC[C@H](NC(=O)OC1C(=O)NCC1(C)C)C(O)C(=O)N[C@H](C)c1ccccc1,[Pd],C1CCOC1,,,,test
US20010014737A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc(Br)c(CNCc2ccc(C(F)(F)F)cc2)c1>>COc1ccc(Br)c(CN(Cc2ccc(C(F)(F)F)cc2)C(=O)OC(C)(C)C)c1,,C1CCOC1,,,,test
US20110112158A1,BrBr.Cc1ccc(F)c(F)c1>>Cc1cc(F)c(F)cc1Br,[Fe],ClCCl,,,,test
US20030130260A1,CO.O=C1CC(C(=O)O)c2ccccc21>>COC(=O)C1CC(=O)c2ccccc21,,CCC(C)(C)O,,O=S(=O)(O)O,,test
US20160251339A1,COc1c(N2CCN(C(=O)C(Cl)(Cl)Cl)CC2)cc(S(=O)(=O)Cl)c2ccccc12.O=Cc1c[nH]c2ccc(Cl)cc12>>COc1c(N2CCN(C(=O)C(Cl)(Cl)Cl)CC2)cc(S(=O)(=O)n2cc(C=O)c3cc(Cl)ccc32)c2ccccc12,,C1CCOC1,,[H-].[Na+],,test
US20130172353A1,CC(C)(C)OC(=O)Nc1ccc(-c2snc(Cl)c2C#N)cc1>>N#Cc1c(Cl)nsc1-c1ccc(N)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040034218A1,CI.Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2c(c1)C(c1cccc(Cl)c1)OCC(=O)N2>>CN1C(=O)COC(c2cccc(Cl)c2)c2cc(C(O)(c3ccc(Cl)cc3)c3cncn3C)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20110288063A1,CCOC(=O)c1nn(C)c2c1C1CCC2(C)C1(C)C>>Cn1nc(CO)c2c1C1(C)CCC2C1(C)C,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],[Cl-].[NH4+],test
US05710301,CC[C@H](C)CBr.Cl[Si](Cl)(Cl)c1ccccc1>>CC[C@H](C)C[Si](Cl)(Cl)c1ccccc1,,C1CCOC1,CCCCCC,II,[Mg],test
US20100137313A1,CCCS(N)(=O)=O.COc1cc(Nc2ncc(-c3cnc(OC)c(C(=O)O)c3)c(-n3nc(C(F)(F)F)cc3C)n2)cc(OC)c1>>CCCS(=O)(=O)NC(=O)c1cc(-c2cnc(Nc3cc(OC)cc(OC)c3)nc2-n2nc(C(F)(F)F)cc2C)cnc1OC,CN(C)c1ccncc1,ClCCl,ClCCl,CCN(CC)CC,C[n+]1ccccc1Cl.[I-],test
US05807854,CC(n1cnc2cc(-c3ccc(C#N)cc3)sc2c1=O)C(O)(Cn1cncn1)c1ccc(F)cc1F.CO>>COC(=N)c1ccc(-c2cc3ncn([C@H](C)[C@](O)(Cn4cncn4)c4ccc(F)cc4F)c(=O)c3s2)cc1,,ClC(Cl)Cl,,,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(-c2ccc(C(C)O)cc2)c2ncnn12>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(-c2ccc(C(C)=O)cc2)c2ncnn12,,CO,,[BH4-].[Na+],,test
US20140088153A1,Cn1nc(C(F)(F)C(F)(F)F)c(C(F)(F)F)c1C(=O)O.O=C(Cl)C(=O)Cl>>Cn1nc(C(F)(F)C(F)(F)F)c(C(F)(F)F)c1C(=O)Cl,,ClCCl,,CN(C)C=O,,test
US04366315,CC1=C(C(=O)O)N2C(=O)C(NC(=O)Cc3ccccc3)[C@H]2S(=O)C1.C[Si](C)(C)NC(=O)c1ccccc1.O=C1CCC(=O)N1Br>>C[Si](C)(C)OC(=O)C1=C(CBr)CS(=O)[C@@H]2C(NC(=O)Cc3ccccc3)C(=O)N12,,ClCCl,,,,test
US20130005771A1,CCCc1nc(C=Cc2ccc(O)c([N+](=O)[O-])c2)no1>>CCCc1nc(C=Cc2ccc(O)c(N)c2)no1,,CCOC(C)=O,,[Na+].[OH-],,test
US20030191118A1,CC(C)(C)NO.COc1ccccc1-c1ccc(C[C@H](NC(=O)c2c(Cl)cccc2Cl)C(=O)O)cc1>>COc1ccccc1-c1ccc(C[C@H](NC(=O)c2c(Cl)cccc2Cl)C(=O)N(O)C(C)(C)C)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US08318959B1,C=CCOCC([N+](=O)[O-])([N+](=O)[O-])[N+](=O)[O-].O=C(OO)c1cccc(Cl)c1>>O=[N+]([O-])C(COCC1CO1)([N+](=O)[O-])[N+](=O)[O-],,ClC(Cl)Cl,,,,test
US04220778,CC(=O)Cl.c1ccc(-c2cccc3c2CNCC3)cc1>>CC(=O)N1CCc2cccc(-c3ccccc3)c2C1,,ClCCl,,CCN(CC)CC,,test
US20040142953A1,COc1cc(NCC(O)c2ccc(C(=O)Nc3ccccc3NC(=O)OC(C)(C)C)cc2)cc(OC)c1OC.O=C(n1ccnc1)n1ccnc1>>COc1cc(N2CC(c3ccc(C(=O)Nc4ccccc4N)cc3)OC2=O)cc(OC)c1OC,,ClCCl,,,,test
US20140349990A1,CCC(=O)C1=C(O)C(=O)N(c2cc(C)c(=O)n(C)c2)C1c1ccc(Cl)cc1.NN>>CCc1n[nH]c2c1C(c1ccc(Cl)cc1)N(c1cc(C)c(=O)n(C)c1)C2=O,,Cc1ccccc1,,CCO,O,test
US05532240,Cc1cc2c(s1)CCCNC2=O.O=C(Cl)CCCCl>>Cc1sc2c(c1C(=O)CCCCl)C(=O)NCCC2,,CC(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20060148858A1,COC(=O)Cc1ccc(O)cc1.Cc1nn(-c2ccccn2)cc1CO>>Cc1nn(-c2ccccn2)cc1COc1ccc(CC(=O)O)cc1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20050277652A1,CCN(CC)CCCN.Cc1cc([N+](=O)[O-])ccc1Oc1ccnc(N)c1.O=C(Cl)Oc1ccccc1>>CCN(CC)CCCNC(=O)Nc1cc(Oc2ccc([N+](=O)[O-])cc2C)ccn1,,C1CCOC1,CN(C)C=O,CCN(CC)CC,,test
US20110034445A1,Cc1cnc(C)c(C(=O)c2ccccc2)n1.NO>>Cc1cnc(C)c(C(=NO)c2ccccc2)n1,,c1ccncc1,,Cl,,test
US20090124625A1,CCN(CC)S(F)(F)F.OC(CC#Cc1ccccn1)c1cnc2ccccc2n1>>FC(CC#Cc1ccccn1)c1cnc2ccccc2n1,,ClCCl,,,,test
US05998439,CC(C)(C)OC(=O)N1CCC(C(=O)c2nc3ccccc3n2CCOCC(F)(F)F)CC1.I>>I.O=C(c1nc2ccccc2n1CCOCC(F)(F)F)C1CCNCC1,,ClCCl,,,,test
US20100056518A1,CC(C)(C)[Si](C)(C)OC1CCCC(N)CCC1>>NC1CCCC(O)CCC1,,CC(C)O,,Cl,,test
US06251912B1,C1CCOC1.CC(C)COC(=O)Cl.Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1>>O=C(C#CCCl)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1,,c1ccncc1,,CN1CCOCC1,,test
US04010202,Br.O=C1c2ccc(O)c(O)c2CCC1NC1CCCC1>>Br.Oc1ccc2c(c1O)CCC(NC1CCCC1)C2O,[Pd],O,,,,test
US20120270882A1,CNC.Cn1ccc(=O)c(O)c1C(O)C(F)(F)F>>CN(C)C(c1c(O)c(=O)ccn1C)C(F)(F)F,,CC#N,,CCN(CC)CC,Cl,test
US05066816,CC(=O)Nc1cc2c(cc1[N+](=O)[O-])[C@@H](O)[C@H](Br)C(C)(C)O2.CC(=O)SC[C@H](C)C(=O)Cl>>CC(=O)Nc1cc2c(cc1[N+](=O)[O-])[C@@H](OC(=O)[C@H](C)CSC(C)=O)[C@H](Br)C(C)(C)O2,,c1ccncc1,,ClCCCl,,test
US20060148862A1,CI.O=[N+]([O-])c1n[nH]c(Br)n1>>Cn1nc([N+](=O)[O-])nc1Br,,CN(C)C=O,,O,[H-].[Na+],test
US20140228303A1,CC(=O)OC[C@@]12CO[C@@](c3ccc(Cl)c(Cc4ccc(C(C)=O)cc4)c3)(O1)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]2OC(C)=O.CCON>>CCON=C(C)c1ccc(Cc2cc([C@]34OC[C@](COC(C)=O)(O3)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]4OC(C)=O)ccc2Cl)cc1,,CCO,,Cl,c1ccncc1,test
US20020169155A1,CCOC(=O)CN1C(=O)c2ccccc2C(=CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc21>>O=C(O)CN1C(=O)c2ccccc2C(=CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc21,,CCOCC,Cl,CCOC(C)=O,[Na+].[OH-],test
US20150111894A1,COc1cc(Br)ccc1OCCCC(N)=O.O=c1[nH]ccc2oc(-c3ccc(Cl)cc3)cc12>>COc1cc(-n2ccc3oc(-c4ccc(Cl)cc4)cc3c2=O)ccc1OCCCC(N)=O,[Cu]I,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=C([O-])[O-].[K+].[K+],test
US20070049593A1,CCC(CC(=O)Cl)C(=O)Cl.COC(=O)c1ccc(Cl)cc1N.O>>CCOC(=O)CCC(=O)Nc1cc(Cl)ccc1C(=O)OC,,Cc1ccccc1,,c1ccncc1,,test
US20160264573A1,CC(C)(C)OC(=O)N1C[C@H](NOC(OCc2ccccc2)c2ccccc2)CC[C@H]1C(=O)O.Oc1cccc2cccnc12>>CC(C)(C)OC(=O)N1C[C@H](NOCc2ccccc2)CC[C@H]1C(=O)Oc1cccc2cccnc12,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US05143935,CCOC(=O)[C@@H]1CC(O)CN1CC.CS(=O)(=O)Cl>>CCOC(=O)[C@@H]1CC(OS(C)(=O)=O)CN1CC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20060276464A1,CNCCNS(=O)(=O)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F.O=C(O)c1cccc(S(=O)(=O)Cl)c1>>CN(CCNS(=O)(=O)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F)S(=O)(=O)c1cccc(C(=O)O)c1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20050159431A1,NCCc1ccc([N+](=O)[O-])cc1.O=C1CCCCC1.O=C=NC(=O)Cl>>O=c1[nH]c(=O)n(CCc2ccc([N+](=O)[O-])cc2)c2c1CCCC2,,Cc1ccccc1,O,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US20090082328A1,CC1(C)OCC(CCOc2cc(F)cc(Nc3ccc(I)cc3F)c2C(N)=O)O1>>NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1OCCC(O)CO,,C1CCOC1,,Cl,,test
US05157114,C#C[Si](C)(C)C.CC(=O)OC[C@H]1O[C@@H](n2cc(I)c(=O)[nH]c2=O)C[C@@H]1F>>CC(=O)OC[C@H]1O[C@@H](n2cc(C#C[Si](C)(C)C)c(=O)[nH]c2=O)C[C@@H]1F,[Cu]I,CCN(CC)CC,,,,test
US20010014684A1,CC(=O)OC(C)=O.COCCOCN(c1onc(C)c1Cl)S(=O)(=O)c1c(C(O)c2cc3c(cc2CCO)OCO3)sc2ncccc12>>COCCOCN(c1onc(C)c1Cl)S(=O)(=O)c1c(C(OC(C)=O)c2cc3c(cc2CCOC(C)=O)OCO3)sc2ncccc12,,c1ccncc1,,CCOC(C)=O,,test
US20090291973A1,CC(C)Br.CCC(C(=O)Nn1c(S)nc2ccccc2c1=O)c1ccc(Cl)cc1>>CCC(C(=O)Nn1c(SC(C)C)nc2ccccc2c1=O)c1ccc(Cl)cc1,,CCO,,Cl,O,test
US20060229314A1,CCOC(=O)c1c(Cl)c2sccc2n(Cc2ccc(OC)cc2)c1=O>>CCOC(=O)c1c(Cl)c2sccc2[nH]c1=O,,O=C(O)C(F)(F)F,,,,test
US07018997B2,COC(=O)c1ccc2c(c1)NC(=O)c1ccccc1O2>>OCc1ccc2c(c1)N=Cc1ccccc1O2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140051692A1,C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OC)c(C)nc3cc(-c4cccc(-c5cc(F)ccc5O[C@@H](C)CC=C)c4)nn23)CC1>>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc3nn2c1N1CCC(C)(CC1)OCCCC[C@H](C)Oc1ccc(F)cc1-c1cccc-3c1,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,CCOC(C)=O,ClCCCl,[BH4-].[Na+],,test
US20110105535A1,CC(=O)O.Cc1ccnc(Cl)c1>>CC(=O)Cc1ccnc(Cl)c1,,C1CCOC1,CCOC(C)=O,CC(C)NC(C)C,[Li]CCCC,test
US20090105218A1,COC(=O)c1ccccc1NC(=O)c1cccc([N+](=O)[O-])c1>>COC(=O)c1ccccc1NC(=O)c1cccc(N)c1,[Pd],CO,,,,test
US20140171422A1,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1CO[Si](C)(C)C(C)(C)C.CI>>CO[C@@H]1C[C@@H](CO[Si](C)(C)C(C)(C)C)N(C(=O)OC(C)(C)C)C1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],[Cl-].[NH4+],test
US20040157886A1,Nc1ccc2c(c1)CCC(=O)N2.O=C(CCl)N1CCC(Oc2ccc(Cl)cc2)CC1>>O=C1CCc2cc(NCC(=O)N3CCC(Oc4ccc(Cl)cc4)CC3)ccc2N1,,CCOCC,,,,test
US20120232056A1,COC(=O)c1ccc2nc(-c3ccc(-c4ccc(F)cc4)o3)c(N(C)C(C)C)nc2c1>>CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1ccc(-c2ccccc2)o1,,CO,O,[Na+].[OH-],,test
US20120087880A1,CC12CCC(C1)C1(C)OC1C2>>CC1C(=O)CC2(C)CCC1C2,,Cc1ccccc1,,CCOCC,FB(F)F,test
US20120172377A1,Cc1ccc2[nH]c3c(c2c1)CN(C)CC3.Fc1ccc(C2(CBr)OCCO2)cc1>>Cc1ccc2c(c1)c1c(n2CC2(c3ccc(F)cc3)OCCO2)CCN(C)C1,,CN1CCCC1=O,,O,[H-].[Na+],test
US20090325924A1,CC(=O)c1ccc(SC2CC2)cc1.CN(C)C=O>>O=C(O)c1ccc(SC2CC2)cc1,,CN(C)C=O,,[K+].[OH-],,test
US20160068532A1,Cc1cc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3cc4c(cc23)CN([C@H](C)c2ccc(F)cc2)C(=O)N4)ccn1>>Cc1cc(-c2n[nH]c3cc4c(cc23)CN([C@H](C)c2ccc(F)cc2)C(=O)N4)ccn1,,O=C(O)C(F)(F)F,,CO,,test
US20140336153A1,BrCc1ccc(I)cc1.N#Cc1ccc(O)cc1>>N#Cc1ccc(OCc2ccc(I)cc2)cc1,,CC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20160235065A1,Brc1cccc(Br)n1.Cc1cccc(-n2nnn(C)c2=O)c1CO>>Cc1cccc(-n2nnn(C)c2=O)c1COc1cccc(Br)n1,,O,,C1CCOC1,[H-].[Na+],test
US06303593B1,O=C(OCC(Cl)(Cl)Cl)N1CCC(CCSc2ccccc2)CC1>>c1ccc(SCCC2CCNCC2)cc1,[Zn],CC(=O)O,,O=C([O-])O.[Na+],,test
US20100168418A1,CCOC(=O)/C=C/c1cc(=O)n(CCN2CCC(NCc3ccc4c(c3)OCCO4)CC2)c2cc(OC)ccc12>>COc1ccc2c(/C=C/C(=O)O)cc(=O)n(CCN3CCC(NCc4ccc5c(c4)OCCO5)CC3)c2c1,,O,,CCO,[Na+].[OH-],test
US04690923,C=C1CC(=O)O1.CSc1ncnc2c(N3CCSCC3)nc(N3CCNCC3)nc12>>CSc1ncnc2c(N3CCSCC3)nc(N3CCN(C(=O)CC(C)=O)CC3)nc12,,C1COCCO1,,,,test
US20100048636A1,COC1(CC[C@H]2COC(C)(C)N2C(=O)OC(C)(C)C)CCCC1>>COC1(CC[C@@H](CO)NC(=O)OC(C)(C)C)CCCC1,,CO,,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US05948817,COc1ccc(-c2ccccc2)c(NC(=O)C(C)(C)C)c1CCO>>Nc1c(-c2ccccc2)ccc2c1CCO2,,O,,Br,,test
US20120040942A1,CC1(C)CCN(c2ccc(CNC(=O)OC(C)(C)C)cc2Br)CC1.N#C[Cu]>>CC1(C)CCN(c2ccc(CNC(=O)OC(C)(C)C)cc2C#N)CC1,,CN(C)C=O,,,,test
US06482986B1,O=CC=C(Cl)c1ccc(Br)c(Cl)c1>>C#Cc1ccc(Br)c(Cl)c1,,C1COCCO1,O,ClCCl,[Na+].[OH-],test
US20030065174A1,CCC(O)CCN(C)C(=O)OC(C)(C)C.Oc1cc(Cl)ccc1Cl>>CCC(CCN(C)C(=O)OC(C)(C)C)Oc1cc(Cl)ccc1Cl,,C1CCOC1,O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04006145,O=S(Cl)Cl.OCc1cc(C(F)(F)F)ccc1Sc1ccccc1>>FC(F)(F)c1ccc(Sc2ccccc2)c(CCl)c1,,c1ccccc1,,,,test
US20040048863A1,BrP(Br)Br.COc1ccc(Cn2nnc(-c3cccc(CO)c3)n2)cc1>>COc1ccc(Cn2nnc(-c3cccc(CBr)c3)n2)cc1,,ClCCl,,,,test
US20050165065A1,CCOC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOC(=O)[C@@H]1C[C@@H](OS(=O)(=O)c2ccc(C)cc2)CN1C(=O)OC(C)(C)C,,c1ccncc1,,,,test
US20060293371A1,CCOC(=O)OCCN(C)C(=O)Cl.CNC(=NCCSCc1nc[nH]c1C)NC#N>>CCOC(=O)OCCN(C)C(=O)n1cnc(CSCCN=C(NC)NC#N)c1C,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20030036652A1,Cln1cnc2cc(I)ccc21.O=C1OC2(CCNCC2)c2ccccc21>>O=C1OC2(CCN(c3nc4cc(I)ccc4[nH]3)CC2)c2ccccc21,,CN1CCCC1=O,,O,,test
US20160200719A1,CC(C)(C)OC(=O)N1CCC(N)CC1.Clc1cnnc2ccc(Br)cc12>>CC(C)(C)OC(=O)N1CCC(Nc2cnnc3ccc(Br)cc23)CC1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20160031879A1,CCOC(=O)Cc1ncccc1Cl.COCCC(Br)C=O>>CCOC(=O)c1cc(CCOC)n2cccc(Cl)c12,,ClCCl,,O=C([O-])O.[Na+],,test
US20160046596A1,COCOc1c(C=O)cc(F)nc1F>>O=Cc1cc(F)nc(F)c1O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100121051A1,Cc1nccc2nc(NCCN3CCNCC3)ccc12.O=Cc1ccccc1>>Cc1nccc2nc(NCCN3CCN(Cc4ccccc4)CC3)ccc12,,CN(C)C=O,,CC(=O)O,,test
US20060142265A1,CN(Cc1cc2ccccc2n1C)C(=O)C=Cc1ccc(N)nc1.O=C1CCC(=O)O1>>CN(Cc1cc2ccccc2n1C)C(=O)/C=C/c1ccc(N2C(=O)CCC2=O)nc1,,C1COCCO1,,,,test
US20080312226A1,Cl.O=C(Nc1cccnc1)N1CCN(c2nc(-c3ccccc3)ns2)CC1>>Cl.O=C(Nc1cccnc1)N1CCN(c2nc(-c3ccccc3)ns2)CC1,,C1CCOC1,CCOC(C)=O,,,test
US20150191434A1,CC(C)(C)OC(=O)C1CC=C(c2cn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccc(F)c23)CC1>>O=C(O)C1CC=C(c2cn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccc(F)c23)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040180925A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCC1(N)CCN(Cc2ccccc2)CC1>>CCC1(NC(=O)OC(C)(C)C)CCN(Cc2ccccc2)CC1,,ClC(Cl)Cl,,,,test
US20050113442A1,NC(=O)[C@@H]1CCCC[C@@H]1N.O=S(=O)(Cl)c1ccc(Cl)cc1>>NC(=O)[C@@H]1CCCC[C@@H]1NS(=O)(=O)c1ccc(Cl)cc1,,ClCCl,,CCN(CC)CC,,test
US20040106627A1,NO.O=Cc1sccc1C1OCCO1>>ON=Cc1sccc1C1OCCO1,,CCO,O,Cl,O=C([O-])O.[Na+],test
US04956359,Fc1ccc(Br)cc1.OC1CN(C(c2ccccc2)c2ccccc2)C1>>Brc1ccc(OC2CN(C(c3ccccc3)c3ccccc3)C2)cc1,,CN(C)C=O,O,[H][H],[H-].[Na+],test
US20030069297A1,Cc1[nH]c(C=O)c(C)c1C(=O)N1C[C@H](C)N[C@H](C)C1.O=C1Cc2c(cccc2-c2cccc(Br)c2)N1>>Cc1[nH]c(C=C2C(=O)Nc3cccc(-c4cccc(Br)c4)c32)c(C)c1C(=O)N1C[C@H](C)N[C@H](C)C1,C1CCNCC1,CCO,,,,test
US20070265268A1,COCOc1cc(COCc2ccccc2)c(C=O)c(OCOC)c1.O>>COCOc1cc(COCc2ccccc2)c(C(=O)O)c(OCOC)c1,,CC(C)(C)O,O,CC=C(C)C,[Na+].[O-]Cl,test
US20140221339A1,COC(=O)c1cc(Br)cc2cn[nH]c12.C[Si](C)(C)CCOCCl>>COC(=O)c1cc(Br)cc2cnn(COCC[Si](C)(C)C)c12,,CN(C)C=O,,[H-].[Na+],,test
US20020052512A1,COC(=O)[C@H](CNC(=O)OCC1c2ccccc2-c2ccccc21)NC(=O)c1ccc(C(=O)NCc2cccc(O)c2)cc1Cl>>COC(=O)[C@H](CN)NC(=O)c1ccc(C(=O)NCc2cccc(O)c2)cc1Cl,,CO,ClCCl,C1CCNCC1,,test
US20040010031A1,Cc1ccc(N)cc1.O=C1NC(=O)C(c2ccc(O)cc2)=C1O>>Cc1ccc(NC2=C(c3ccc(O)cc3)C(=O)NC2=O)cc1,,CCOC(C)=O,CN1CCCC1=O,,,test
US20110034469A1,CC(C)(C)OC(=O)N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1c1ccnn1Cc1ccc(F)cc1)C1CCCCC1>>N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1c1ccnn1Cc1ccc(F)cc1)C1CCCCC1,,CCOC(C)=O,,Cl,,test
US20070010511A1,COCCCN1C(=O)CCc2ccc(COC3CN(C(=O)OCc4ccccc4)CCC3c3ccc(O)cc3)cc21.Cc1ccc(S(=O)(=O)OCCCOC(C)c2ccccc2)cc1>>COCCCN1C(=O)CCc2ccc(COC3CN(C(=O)OCc4ccccc4)CCC3c3ccc(OCCCOC(C)c4ccccc4)cc3)cc21,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04642308,Nc1ccc2ccc(Cl)nc2n1.O=C(O)c1cccs1>>O=C(Nc1ccc2ccc(Cl)nc2n1)c1cccs1,,O,,CCO,,test
US20070270587A1,O=C1Nc2ccc(S(=O)(=O)N3CCCC3)cc2C1=O.OCCCO>>O=C1Nc2ccc(S(=O)(=O)N3CCCC3)cc2C12OCCCO2,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090137580A1,COC(=O)c1cc(N)cc(C(F)(F)F)c1.Cn1ccc2ncnc(Oc3ccc(N)c(Cl)c3)c21.O=C(Cl)Oc1ccccc1>>COC(=O)c1cc(NC(=O)Nc2ccc(Oc3ncnc4ccn(C)c34)cc2Cl)cc(C(F)(F)F)c1,,CN1CCCC1=O,,c1ccncc1,,test
US04691044,CCCCCCCC/C=C\CCCCCCCCO.COC(=O)CCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1>>CCCCCCCC/C=C\CCCCCCCCOC(=O)CCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1,,Cc1ccccc1,,,,test
US20130116243A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)C(=NO)CCC4)cc2)CCC1>>NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)C(=NO)CCC4)cc2)CCC1,,O=C(O)C(F)(F)F,,,,test
US20110136780A1,C1CCNC1.CC(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)O>>CC(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)N1CCCC1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120214803A1,O=[N+]([O-])c1c(C(O)c2ccc(C(F)(F)F)cc2)ccc2cccnc12>>O=C(c1ccc(C(F)(F)F)cc1)c1ccc2cccnc2c1[N+](=O)[O-],,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20120245136A1,COC(=O)C1=CC2(CCN(C(=O)OC(C)(C)C)CC2)Oc2ccccc21>>COC(=O)C1CC2(CCN(C(=O)OC(C)(C)C)CC2)Oc2ccccc21,[Pd],CC(C)O,,,,test
US20050014755A1,NN.Nc1nnc(Cc2ccc(F)cc2)o1>>Nc1nnc(Cc2ccc(F)cc2)n1N,,O,,,,test
US20060128790A1,C=CC1(O)CCC1.Cc1cc(O)cc(C)c1O>>Cc1cc2c(c(C)c1O)CCC1(CCC1)O2,,C1COCCO1,CCOC(C)=O,,,test
US20110124637A1,CC(C)(C)OC(=O)Nc1ccc(CN2CCOCC2)cn1>>Nc1ccc(CN2CCOCC2)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090156600A1,CCC(=O)C(Cc1ccc(S(=O)(=O)N2CCOCC2)cc1)C(=O)OC.COC(=O)COc1ccc(F)c(N)c1>>CCc1[nH]c2c(F)ccc(OCC(=O)OC)c2c(=O)c1Cc1ccc(S(=O)(=O)N2CCOCC2)cc1,,O,,C1COCCO1,,test
US20150087699A1,Cc1cccc2oc([C@@H](C)OCc3ccccc3)c(-c3ccccc3)c(=O)c12>>Cc1cccc2oc([C@@H](C)O)c(-c3ccccc3)c(=O)c12,,ClCCl,,BrB(Br)Br,,test
US20110183988A1,COC(=O)Cl.Nc1ccc(F)cc1F>>COC(=O)Nc1ccc(F)cc1F,,ClCCl,,c1ccncc1,,test
US20130059835A1,CC(=O)c1cc(Cl)c(C)c(Br)c1O.CCI>>CCOc1c(C(C)=O)cc(Cl)c(C)c1Br,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090253689A1,CC(C)(C)OC(=O)NCc1cc2nccn2cc1-c1ccc(Cl)cc1Cl>>NCc1cc2nccn2cc1-c1ccc(Cl)cc1Cl,,ClCCl,O=C(O)C(F)(F)F,,,test
US20060094767A1,CS(=O)(=O)Cl.C[C@@](O)(CO)Cn1cc([N+](=O)[O-])nc1Cl>>C[C@@](O)(COS(C)(=O)=O)Cn1cc([N+](=O)[O-])nc1Cl,,c1ccncc1,,Cl,,test
US20060229337A1,CCOC(=O)c1ccc(Nc2nc(Br)cn(C)c2=O)cc1.Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1B1OC(C)(C)C(C)(C)O1>>CCOC(=O)c1ccc(Nc2nc(-c3cccc(NC(=O)c4ccc(C(C)(C)C)cc4)c3C)cn(C)c2=O)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20080255085A1,CN1CCN(C(=O)c2ccc(-c3nc4c(Cl)ccnc4[nH]3)cc2)CC1>>CN1CCN(Cc2ccc(-c3nc4c(Cl)ccnc4[nH]3)cc2)CC1,,CO,,,,test
US20150353552A1,CC(C)(C)OC(=O)N1C2CCC1C(O)C2.CCn1c(-c2cnc(C)nc2)nc2c(Cl)ncnc21>>CCn1c(-c2cnc(C)nc2)nc2c(OC3CC4CCC3N4C(=O)OC(C)(C)C)ncnc21,,C1CCOC1,,[H-].[Na+],,test
US20110263647A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H](N)Cc1ccc2c(c1)OCCO2>>COC(=O)[C@H](Cc1ccc2c(c1)OCCO2)NC(=O)OC(C)(C)C,,CO,,CCN(CC)CC,,test
US20160016954A1,Fc1cccc2c1C1(CCC1)CCN2.NC(=O)CBr>>NC(=O)CN1CCC2(CCC2)c2c(F)cccc21,,CN(C)C=O,,[H-].[Na+],,test
US20100305096A1,CC(=O)OC(C)(C)C(=O)Cl.CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CCNCC3)sc2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CCN(C(=O)C(C)(C)OC(C)=O)CC3)sc2n1,,ClCCl,,CCN(CC)CC,,test
US20130150361A1,BrCc1cccc(Br)c1.FC1(F)CCNCC1>>FC1(F)CCN(Cc2cccc(Br)c2)CC1,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US20130005677A1,C=C1[C@H](OCc2ccccc2)[C@@H]2OC(C)(C)O[C@@H]2[C@H]1COC(C)(C)C>>C=C1[C@H](OCc2ccccc2)[C@@H](O)[C@@H](O)[C@H]1CO,,CO,,Cl,O=C([O-])O.[Na+],test
US20050143443A1,CCOC(=O)c1cc(CC(C)c2ccccc2)[nH]n1>>CC(Cc1cc(C(=O)O)n[nH]1)c1ccccc1,,CO,,[Na+].[OH-],,test
US20160122361A1,CCOC(=O)/C=C/c1cnc(SC)nc1NC1CCCC1.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)/C=C/c1cnc(S(C)=O)nc1NC1CCCC1,,ClCCl,,,,test
US20130053345A1,CCCc1cnc(N2CCC(Oc3nc4ccc(C5=CCN(S(=O)(=O)CCNC(=O)COC(C)=O)CC5)cc4s3)CC2)nc1>>CCCc1cnc(N2CCC(Oc3nc4ccc(C5=CCN(S(=O)(=O)CCNC(=O)CO)CC5)cc4s3)CC2)nc1,,C1CCOC1,,[Li+].[OH-],,test
US20070149542A1,CSc1cccc(C2(O)CCN(C(=O)OC(C)(C)C)CC2)c1F>>CSc1cccc(C2=CCNCC2)c1F,,O=C(O)C(F)(F)F,,,,test
US20110082133A1,CCC[C@H]1CCCN1Cc1c(Cl)cc(Cl)c(=O)n1CCc1ccc(C(=O)O)cc1.N>>CCC[C@H]1CCCN1Cc1c(Cl)cc(Cl)c(=O)n1CCc1ccc(C(N)=O)cc1,,C1COCCO1,ClC(Cl)Cl,O,O=C(n1ccnc1)n1ccnc1,test
US20160108027A1,COCC1COC(C)(CCO)CN1.COc1cc(C(=O)O)cc2nc(NCc3cc(Cl)ccn3)oc12>>COCC1COC(C)(CCO)CN1C(=O)c1cc(OC)c2oc(NCc3cc(Cl)ccn3)nc2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080096877A1,CCOC(=O)c1cc2ccc(Cl)c(N(C)S(=O)(=O)c3cccs3)c2[nH]1>>CN(c1c(Cl)ccc2cc(C(=O)O)[nH]c12)S(=O)(=O)c1cccs1,,CO,,C1CCOC1,[Na+].[OH-],test
US20100160258A1,CC(F)(F)[C@H]1CC[C@@H](OCc2ccccc2)CC1>>CC(F)(F)[C@@H]1CC[C@H](O)CC1,[Pd],CO,,[H][H],,test
US20120015978A1,CO.O=C(O)c1cccc2cccnc12>>COC(=O)c1cccc2cccnc12,,CO,Cc1ccccc1,CC(=O)O,,test
US20100249123A1,COc1ccc(C(=O)Nc2ccc(C(C)(C)CN)cc2)cc1OC.O=C(O)Cc1ccccc1[N+](=O)[O-]>>COc1ccc(C(=O)Nc2ccc(C(C)(C)CNC(=O)Cc3ccccc3[N+](=O)[O-])cc2)cc1OC,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20160168100A1,COc1cc(C)c(/C=C/C2NCCc3cc(OCc4ccccc4)c(OC)cc32)cc1OCc1ccccc1.O=C(O)c1cccnc1>>COc1cc(C)c(/C=C/C2c3cc(OC)c(OCc4ccccc4)cc3CCN2C(=O)c2cccnc2)cc1OCc1ccccc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20010051657A1,Cc1cc(NC(=O)COCc2ccccc2)cc(C)c1Oc1ccc(O)c(C(=O)N(C)C2CCC2)c1>>Cc1cc(NC(=O)CO)cc(C)c1Oc1ccc(O)c(C(=O)N(C)C2CCC2)c1,[Pd],CCOC(C)=O,,,,test
US20130190249A1,CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)cn1.O=[N+]([O-])c1cccc(Br)c1>>O=[N+]([O-])c1cccc(-c2cn[nH]c2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20140296271A1,C#Cc1cc(Nc2nccc(Oc3ccc(NC(=O)OC(C)(C)C)c4ccccc34)n2)cc(C(=O)NCCOCCOCCOC)c1>>C#Cc1cc(Nc2nccc(Oc3ccc(N)c4ccccc34)n2)cc(C(=O)NCCOCCOCCOC)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080139631A1,BrBr.CCCc1cc2cc(OCc3ccccc3)ccc2n1S(=O)(=O)c1ccccc1>>CCCc1cc2c(Br)c(OCc3ccccc3)ccc2n1S(=O)(=O)c1ccccc1,,CC(=O)O,,O,,test
US20130190289A1,COCCN1CC[C@H](N(C(=O)[C@@H]2CC[C@@H](C)CC2)c2cc(C#CC(C)(C)C)sc2C(=O)O)C1=O>>C[C@H]1CC[C@H](C(=O)N(c2cc(C#CC(C)(C)C)sc2C(=O)O)[C@H]2CCN(CCO)C2=O)CC1,,ClCCl,,BrB(Br)Br,,test
US20110251169A1,CC1(C)CN(c2ccc(Cl)nn2)C(=O)N1.CI>>CN1C(=O)N(c2ccc(Cl)nn2)CC1(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20120202834A1,CCOC(=O)c1ccc(I)cc1.O=CC1CCC1>>CCOC(=O)c1ccc(C(O)C2CCC2)cc1,,C1CCOC1,,,,test
US20020035258A1,CON=C1CNCC12CN(C(=O)OC(C)(C)C)C2.O=C(O)c1cn(C2CC2)c2nc(Cl)c(F)cc2c1=O>>CON=C1CN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC12CN(C(=O)OC(C)(C)C)C2,,CC#N,,,,test
US20030199510A1,COc1cc2c(cc1OC)C(=O)CC2.O=C1Cc2ccccc2N1>>COc1cc2c(cc1OC)C(=C1C(=O)Nc3ccccc31)CC2,,CCO,CN(C)C=O,C1CCNCC1,Cl,test
US20040039205A1,C=C(C(=O)OC)[C@@H](O)c1ccccc1>>C=C(C(=O)O)[C@@H](O)c1ccccc1,,CO,O,[K+].[OH-],,test
US20090023801A1,COP(OC)OCC(=O)OC(C)(C)C.O=C(c1ccc(F)cc1)C(F)(F)F>>CC(C)(C)OC(=O)C=C(c1ccc(F)cc1)C(F)(F)F,,ClCCl,,CN(C)C(=N)N(C)C,,test
US20160083365A1,C[C@H](N[S@@](=O)C(C)(C)C)c1cc2cc(Cl)c(Br)cc2[nH]c1=O>>C[C@H](N)c1cc2cc(Cl)c(Br)cc2[nH]c1=O,,CCOCC,CO,Cl,,test
US03970602,C=CN.C=Cn1c2ccccc2c2ccccc21.O=[N+]([O-])c1ccc(F)c([N+](=O)[O-])c1>>C=CNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-].C=Cn1c2ccccc2c2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06323222B1,C[C@@H]1C[C@H](O)C[C@H](c2cccc(Cl)c2)N1.O=C(O)C(=O)O>>C[C@@H]1C[C@H](O)C[C@H](c2cccc(Cl)c2)N1.O=C(O)C(=O)O,,CC(C)O,,,,test
US20080021038A1,CC(C)(C)OC(=O)N1CCC(N)CC1.CS(=O)(=O)c1ccc(F)c([N+](=O)[O-])c1.CS(C)=O>>CC1(Nc2ccc(S(C)(=O)=O)cc2[N+](=O)[O-])CCN(C(=O)OC(C)(C)C)CC1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110123601A1,CCO[Si](CCCN)(OCC)OCC.O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccc(N=C=S)cc21>>O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccc(N=C=S)cc21.[SiH4],,CCO,,,,test
US20100093757A1,COC(=O)[C@H](COCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)Oc1ncnc2c1cnn2-c1cc(C#N)ccc1C.Cc1ccc(N)nc1>>Cc1ccc(NC(=O)[C@H](COCCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)Oc2ncnc3c2cnn3-c2cc(C#N)ccc2C)nc1,,Cc1ccccc1,,C[Al](C)C,,test
US20060160851A1,O=C(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)N1CCC(O)CC1.Oc1ccc(-n2ccnc2)cc1>>O=C(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)N1CCC(Oc2ccc(-n3ccnc3)cc2)CC1,,CCOCC,,CCOC(C)=O,Cl,test
US20120214803A1,O=[N+]([O-])c1cc(F)c(F)cc1S(=O)(=O)Nc1ccc(Cl)c2cccnc12>>Nc1cc(F)c(F)cc1S(=O)(=O)Nc1ccc(Cl)c2cccnc12,Cl,CCO,,Cl[Sn]Cl,,test
US20040127527A1,ClCCl.O=S(Cl)Cl.OCc1[nH]c(-c2cccc(F)c2)nc1-c1cccnc1>>Cl.Cl.Fc1cccc(-c2nc(-c3cccnc3)c(CCl)[nH]2)c1,,ClCCl,,,,test
US20040067983A1,CCOC(=O)C(C)OC(=O)[C@@H](CC#CC(=O)c1ccc(Cl)c(Cl)c1)c1cccc(C)c1.COc1ccc(NN)cc1>>CCOC(=O)C(C)OC(=O)[C@@H](Cc1cc(-c2ccc(Cl)c(Cl)c2)n(-c2ccc(OC)cc2)n1)c1cccc(C)c1,,C1CCOC1,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US07820704B2,CC(C)c1ccc(-c2csc(N(CCC(=O)O)Cc3cccs3)n2)cc1.CS(N)(=O)=O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)c1ccc(-c2csc(N(CCNC(=O)NS(C)(=O)=O)Cc3cccs3)n2)cc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20050065340A1,Brc1ccccn1.COc1cc(-c2nc3ccccc3o2)ccc1B1OC(C)(C)C(C)(C)O1>>COc1cc(-c2nc3ccccc3o2)ccc1-c1cccc(Br)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20090143385A1,Cc1onc(-c2cccc(F)c2)c1CO.Clc1ccc(Cl)nn1>>Cc1onc(-c2cccc(F)c2)c1COc1ccc(Cl)nn1,,C1CCOC1,,[H-].[Na+],,test
US20050049262A1,BrCc1ccccc1.CC(=O)O[C@@H](C)CCCCn1c(=O)c2[nH]c(CO)nc2n(C)c1=O>>CC(=O)O[C@@H](C)CCCCn1c(=O)c2c(nc(CO)n2Cc2ccccc2)n(C)c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030092700A1,N#CCCl.c1ccc(CN2CC3CC2CN3)cc1>>N#CCN1CC2CC1CN2Cc1ccccc1,,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20110274638A1,CC#CCOC1(c2ccccc2C)CN(C(=O)OC(C)(C)C)C1.Cl>>CC#CCOC1(c2ccccc2C)CNC1.Cl,,CCOC(C)=O,,,,test
US20090105217A1,NNC(=O)c1ccc(NC(=O)c2ccccc2F)cc1.S=C=NCCCN1CCCCC1>>O=C(NNC(=S)NCCCN1CCCCC1)c1ccc(NC(=O)c2ccccc2F)cc1,,CN(C)C=O,,,,test
US20060128732A1,COc1c(O)ccc(C=O)c1[N+](=O)[O-].N>>COc1c(O)ccc(C#N)c1[N+](=O)[O-],,C1CCOC1,,II,,test
US20040157859A1,COc1ccc(C2CC(=O)N(c3cccc(C(N)=O)c3)C2)c(OCc2ccccc2)c1>>COc1ccc(C2CC(=O)N(c3cccc(C#N)c3)C2)c(OCc2ccccc2)c1,[Pd],CCO,CCOC(C)=O,,,test
US05391817,COc1cc(CCl)ccc1C12CC3CC(CC(C3)C1)C2.[I-]>>COc1cc(CI)ccc1C12CC3CC(CC(C3)C1)C2,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06642233B1,CC(C)(O)C#N.O=C1CCCCC1.c1ccc(CN2CCNCC2)cc1>>N#CC1(N2CCN(Cc3ccccc3)CC2)CCCCC1,,CC(=O)N(C)C,,O=S(=O)([O-])[O-].[Mg+2],,test
US04146715,Cl.Nc1nc(N)c2ncn(COCCO)c2n1>>Cl.Nc1nc(N)c2ncn(COCCO)c2n1,,CCO,,CCOCC,,test
US20100197939A1,CCOC(=O)/C=C/C1COC(C)(C)O1.C[N+](=O)[O-]>>CCOC(=O)C[C@@H](C[N+](=O)[O-])[C@H]1COC(C)(C)O1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040023999A1,COc1ccc(F)cc1C(C)(C)CC(=O)CC1CCCCC1.Cc1cc(C)nc(C)c1>>COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc(C)cc(C)n1)CC1CCCCC1,,C1CCOC1,,[Li]C(C)(C)C,,test
US05665718,C=CCBr.CCN(C(C)C)C(C)C.ClCCl.NCc1noc(-c2ncn3c2[C@@H]2CCN2C(=O)c2c-3cccc2C(F)(F)F)n1>>C=CCN(CC=C)Cc1noc(-c2ncn3c2[C@@H]2CCN2C(=O)c2c-3cccc2C(F)(F)F)n1,,ClCCl,,,,test
US04115568,CCOC(=O)c1ccsc1N.O=[N+]([O-])c1cc(F)ccc1F>>CCOC(=O)c1ccsc1Nc1ccc(F)cc1[N+](=O)[O-],,CCO,,,,test
US05026856,Brc1ccc2c(c1)CNC2.O=C(O)c1cn(-c2ccc(F)cc2F)c2c(F)c(F)c(F)cc2c1=O>>O=C(O)c1cn(-c2ccc(F)cc2F)c2c(F)c(N3Cc4ccc(Br)cc4C3)c(F)cc2c1=O,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20100041635A1,CC(=O)c1ccc(-c2ccc(C(=O)N3CCCN(C)CC3)cc2)o1.O=C1Cc2cc(Cl)ccc2N1>>CC(=C1C(=O)Nc2ccc(Cl)cc21)c1ccc(-c2ccc(C(=O)N3CCCN(C)CC3)cc2)o1,,Cc1ccccc1,,C1CCNCC1,,test
US20110224304A1,N.O=C(O)Cc1ccccc1-c1ccccc1F>>NC(=O)Cc1ccccc1-c1ccccc1F,,C1CCOC1,ClCCl,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US05919824,CN(C(=O)CBr)c1ccccc1.O=[N+]([O-])c1ccccc1O>>CN(C(=O)COc1ccccc1[N+](=O)[O-])c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US03931407,CC(C)(C)C1CCc2c(cc(-c3ccccc3)n2-c2ccc(O)c(C(=O)O)c2)C1>>CC(C)(C)c1ccc2c(c1)cc(-c1ccccc1)n2-c1ccc(O)c(C(=O)O)c1,[Pd],Cc1ccccc1C,,,,test
US20110160198A1,CC(C)(C)CCO.COC(=O)[C@H](Cc1ccc(-c2ccnc(C)c2C)cc1)NC(=O)[C@@H]1Cc2cc3c(cc2CN1C(=O)c1ccccc1)O[C@@H](c1ccc(O)cc1)CO3>>Cc1nccc(-c2ccc(C[C@H](NC(=O)[C@@H]3Cc4cc5c(cc4CN3C(=O)c3ccccc3)O[C@@H](c3ccc(OCCC(C)(C)C)cc3)CO5)C(=O)O)cc2)c1C,,ClCCl,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080249101A1,CC(C)(C)OC(=O)N1CCC(N)CC1.COC(=O)c1ccccc1CBr>>CC(C)(C)OC(=O)N1CCC(N2Cc3ccccc3C2=O)CC1,,CCN(CC)CC,CO,,,test
US20040102450A1,CC#N.CC(C)(C)OC(=O)n1c(CBr)cc2cc(Cl)ccc21.COC(=O)C1CNCC(=O)N1Cc1ccc(C#N)c(N=C(c2ccccc2)c2ccccc2)c1>>COC(=O)C1CN(Cc2cc3cc(Cl)ccc3[nH]2)CC(=O)N1Cc1ccc2c(N)ncnc2c1,,CCOCC,O,O=C([O-])[O-].[K+].[K+],,test
US20100256048A1,COC(=O)[C@@H]1CC[C@@H](C(=O)NNC(=O)c2ccc(Br)cc2)CC1.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>COC(=O)[C@@H]1CC[C@@H](c2nnc(-c3ccc(Br)cc3)s2)CC1,,O,,C1CCOC1,[Na+].[OH-],test
US20110166169A1,CC1(C)OB(c2ccc(C#N)nc2)OC1(C)C.O=S(=O)(Oc1cccc2[nH]c3ccccc3c12)C(F)(F)F>>N#Cc1ccc(-c2cccc3[nH]c4ccccc4c23)cn1,,C1COCCO1,O,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],test
US20140099333A1,O=C1NCC[C@@H]1O.Oc1ccc(Oc2ccc(F)cc2)nc1>>O=C1NCC[C@H]1Oc1ccc(Oc2ccc(F)cc2)nc1,,C1CCOC1,ClCCl,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150141400A1,CC(C)(C)OC(=O)N1CCC(O)CC1.O=C(O)c1cc(Cl)c(F)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)N1CCC(Oc2cc([N+](=O)[O-])c(C(=O)O)cc2Cl)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US20150252030A1,Cc1cc(-c2ccoc2)cc(C)c1OCC(=O)[O-].NN>>Cc1cc(-c2ccoc2)cc(C)c1OCC(=O)NN,,CCO,,,,test
US05686482,COC(=O)c1cc(N)c(OC)cc1OC.Cl>>COC(=O)c1cc(Cl)c(OC)cc1OC,,CC(C)=O,O,O=N[O-].[Na+],,test
US20130059832A1,CC(C)(C)OC(=O)NC1(C(=O)O)COC1.Cc1ccc(C(N)=NO)cc1NC(=O)c1cnc2ccccn12>>Cc1ccc(-c2noc(C3(NC(=O)OC(C)(C)C)COC3)n2)cc1NC(=O)c1cnc2ccccn12,,CN1CCCC1=O,,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US04048326,CCCCc1ccc(N)c([N+](=O)[O-])c1>>CCCCc1ccc(N)c(N)c1,O=[Pt],CCO,,[H][H],,test
US20030130328A1,COc1cccc(C(=O)CC#N)c1.NN>>COc1cccc(-c2cc(N)[nH]n2)c1,,CCO,,,,test
US20160009714A1,C[C@H]1CN(c2ccncc2NC(=O)c2ccc3ccc(N4CCC(C(F)(F)F)C4)cc3n2)C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C>>C[C@H]1CN(c2ccncc2NC(=O)c2ccc3ccc(N4CCC(C(F)(F)F)C4)cc3n2)C[C@@H](N)[C@@H]1O,,Cl,,C1COCCO1,,test
US20140045689A1,CCN1C(=O)C(Cl)=C(Cl)C1=O.Nc1ccccc1O>>CCN1C(=O)C(Cl)=C(Nc2ccccc2O)C1=O,,CCO,,,,test
US20150112067A1,C=O.CC(=O)Cc1c(F)ccc(F)c1F>>C=C(C(C)=O)c1c(F)ccc(F)c1F,,CC#N,,C1CCNCC1,CC(=O)O,test
US20120101086A1,C=CC(=O)OC(C)(C)C.Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(C#N)c3)s1)CCNC2>>Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(C#N)c3)s1)CCN(CCC(=O)OC(C)(C)C)C2,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20040110804A1,CNCCN1CC(C(=O)N(C)Cc2ccc(Cl)c(Cl)c2)=C(O)C1=O.CS(=O)(=O)Cl>>CN(Cc1ccc(Cl)c(Cl)c1)C(=O)C1=C(O)C(=O)N(CCN(C)S(C)(=O)=O)C1,,ClCCl,,CCN(CC)CC,,test
US20100292210A1,Clc1ccc2c(n1)OC(c1ccccn1)CNC2.N#CCBr>>N#CCN1Cc2ccc(Cl)nc2OC(c2ccccn2)C1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20090005370A1,FC(F)(F)c1onc(-c2ccccc2)c1-c1c[nH]cn1.Fc1ccc(C(F)(F)F)cc1>>FC(F)(F)c1ccc(-n2cnc(-c3c(-c4ccccc4)noc3C(F)(F)F)c2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(C)(C)O)CC2)c2ncnn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(C)(C)O)CC2)c2ncnn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20060052426A1,BrCc1ccccc1Br.Oc1ccccc1>>Brc1ccccc1COc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20090291950A1,COc1ccc2c(Cl)nccc2c1OC1CCCC1.Nc1c(Cl)cccc1Cl>>COc1ccc2c(Nc3c(Cl)cccc3Cl)nccc2c1OC1CCCC1,,CN(C)C=O,,,,test
US04489078,CI.S=C1c2nc[nH]c2N(Cc2ccc(Cl)cc2)C2=NCCN12>>CSC1=C2N=CN=C2N(Cc2ccc(Cl)cc2)C2=NCCN21,,CCO,,O,[Na+].[OH-],test
US20090197863A1,NC(=O)c1cccc2nc(-c3ccc(-c4ccccn4)cc3F)oc12>>NC(=O)c1cccc2nc(-c3ccc(C4CCCCN4)cc3F)oc12,O=[Pt]=O,CO,,[H][H],,test
US20020022002A1,CC(=O)c1ccc2cc(O)ccc2c1.CCNCCO>>CCN(CCO)c1ccc2cc(C(C)=O)ccc2c1,,CCOC(C)=O,,O,,test
US04640922,CCOC(=O)C1C(c2cccc([N+](=O)[O-])c2)N=C(C)NC1(C)O>>CCOC(=O)C1=C(C)NC(C)N=C1c1cccc([N+](=O)[O-])c1,,O=P(Cl)(Cl)Cl,,,,test
US05698526,C[C@@H]1CC[C@@]2(OC1)O[C@H]1C[C@H]3[C@@H]4CC[C@H]5C[C@@H](O)CC[C@]5(C)[C@H]4CC(=O)[C@]3(C)[C@H]1[C@@H]2C>>C[C@@H]1CC[C@@]2(OC1)O[C@H]1C[C@H]3[C@@H]4CC[C@H]5C[C@@H](O)CC[C@]5(C)[C@H]4C[C@H](O)[C@]3(C)[C@H]1[C@@H]2C,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080293770A1,O=C1CCOCC1.O=c1[nH]c2cc(F)c(Br)cc2n1C1CCNCC1>>O=c1[nH]c2cc(F)c(Br)cc2n1C1CCN(C2CCOCC2)CC1,,ClCCl,,CCN(CC)CC,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20070111988A1,CN.COc1ccc2c3c(ccc2c1)-c1ccc(C(=O)O)cc1OC3c1ccc(OCCN2CCCCC2)cc1.O=C(Cl)C(=O)Cl>>CNC(=O)c1ccc2c(c1)OC(c1ccc(OCCN3CCCCC3)cc1)c1c-2ccc2cc(OC)ccc12.Cl,,ClCCl,,,,test
US05102880,CCc1nc2c(C)cc(C)nc2[nH]1.O=[N+]([O-])c1ccccc1-c1ccc(CBr)cc1>>CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2[N+](=O)[O-])cc1,,CN(C)C=O,,[H-].[Na+],,test
US20120114739A1,C[Si](C)(C)CCOCn1cc(C2CCC(=O)CC2)cn1.O=S(=O)(N(c1ccc(Cl)cn1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>C[Si](C)(C)CCOCn1cc(C2CC=C(OS(=O)(=O)C(F)(F)F)CC2)cn1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20120225877A1,ClCc1cnc(Cl)s1.OCC1COC2(CCN(CCc3ccccc3)CC2)O1>>Clc1ncc(COCC2COC3(CCN(CCc4ccccc4)CC3)O2)s1,,Cc1ccccc1,,[H-].[Na+],,test
US05631264,C=C(c1ccoc1)c1ccoc1.COc1ccc[n+]2cc3ccccc3cc12.[O-][Cl+3]([O-])([O-])[O-]>>COc1c(-c2ccoc2)cc[n+]2c1Cc1ccccc1C2.[O-][Cl+3]([O-])([O-])[O-],,C[N+](=O)[O-],,,,test
US20120252853A1,Cc1cc2cc([C@H](N[S@@](=O)C(C)(C)C)C(F)(F)F)ccc2n1S(=O)(=O)c1ccccc1>>Cc1cc2cc([C@H](N[S@@](=O)C(C)(C)C)C(F)(F)F)ccc2[nH]1,,CO,,O,[K+].[OH-],test
US20110275611A1,Clc1cc(Cl)nc(Cl)n1.O=C(NC1CCCCC1)C1CCC(C(F)(F)F)NC1>>O=C(NC1CCCCC1)C1CCC(C(F)(F)F)N(c2cc(Cl)nc(Cl)n2)C1,,C1COCCO1,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20140206663A1,CCOC(=O)[C@@H](C)N1C(=S)COc2cc(Br)ccc21.NN>>C[C@@H]1C(=O)NN=C2COc3cc(Br)ccc3N21,,CCO,,O,,test
US20080132495A1,CS(=O)(=O)O.O=C(Nc1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1)NC1CC1>>CS(=O)(=O)O.O=C(Nc1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1)NC1CC1,,CCOC(C)=O,CO,,,test
US20020107269A1,C#CCOC(=O)Cl.Nc1ccc(Cl)c(-c2nc3ccccc3o2)c1>>C#CCOC(=O)Nc1ccc(Cl)c(-c2nc3ccccc3o2)c1,,C1CCOC1,,c1ccncc1,,test
US04315933,CC(=O)OC(C)=O.Nc1ccc(-c2ncc(C(=O)O)c(O)n2)cc1>>CC(=O)Nc1ccc(-c2ncc(C(=O)O)c(O)n2)cc1,,CC(=O)O,,,,test
US20120108572A1,C=O.COc1c(NC(=O)c2ccc(C)c(Oc3cc(CC4CCNCC4)ncn3)c2)cc(C(C)(C)C)cc1NS(C)(=O)=O>>COc1c(NC(=O)c2ccc(C)c(Oc3cc(CC4CCN(C)CC4)ncn3)c2)cc(C(C)(C)C)cc1NS(C)(=O)=O,[Pd],CO,,[H][H],,test
US20090036503A1,CC(CC(F)(F)F)C(=O)O.Cn1c(-c2ccccc2C(F)(F)F)nnc1C12CCC(C(=O)NN)(CC1)CC2>>CC(CC(F)(F)F)C(=O)NNC(=O)C12CCC(c3nnc(-c4ccccc4C(F)(F)F)n3C)(CC1)CC2,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US05447943,CC1(C)Oc2ccc(Br)cc2C(n2ccccc2=O)=C1CNO.C[Si](C)(C)N=C=S>>CC1(C)Oc2ccc(Br)cc2C(n2ccccc2=O)=C1CN(O)C(N)=S,,C1CCOC1,,O,,test
US20140228340A1,N#Cc1cc(Br)ccc1F.OCC1CC1>>N#Cc1cc(Br)ccc1OCC1CC1,,CN(C)C=O,,[H-].[Na+],,test
US06821992B1,NCc1ncc(C(F)(F)F)cc1Cl.S=C=NCc1ccccc1>>FC(F)(F)c1cnc(CNC(=S)NCc2ccccc2)c(Cl)c1,CCN(CC)CC,C1CCOC1,,Cl,,test
US20100136136A1,CCOC(=O)CBr.O=[N+]([O-])c1ccc(O)cc1[N+](=O)[O-]>>CCOC(=O)COc1ccc([N+](=O)[O-])c([N+](=O)[O-])c1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100286211A1,Clc1ncc(Br)cn1.c1c[nH]cn1>>Brc1cnc(-n2ccnc2)nc1,,CN1CCCC1=O,O,CCO,O=C([O-])[O-].[K+].[K+],test
US05910495,COc1ccc(Cn2c(=O)c(=NNc3ccccc3)c(=O)n(-c3ccccc3)c3ccccc32)cc1>>COc1ccc(CN2C(=O)C(N)C(=O)N(c3ccccc3)c3ccccc32)cc1,[Zn],CC(=O)O,,,,test
US20130096303A1,CC(C)(C)OC(=O)C[C@H]1C[C@@H](CO)OC(C)(C)O1.CS(=O)(=O)Cl>>CC1(C)O[C@H](COS(C)(=O)=O)C[C@H](CC(=O)O)O1,,O,,CCN(CC)CC,ClCCl,test
US20150119385A1,COCCOc1cc(N)ncc1C#N.O=C(Cl)Oc1ccccc1>>COCCOc1cc(NC(=O)Oc2ccccc2)ncc1C#N,,C1CCOC1,,c1ccncc1,,test
US04233305,COC(=O)c1cc(F)ccc1N.Clc1ccnc2c(Cl)cccc12>>COC(=O)c1cc(F)ccc1Nc1ccnc2c(Cl)cccc12,,Cl,,,,test
US04293675,COP(C)(=O)OC.Cl[Sb](Cl)(Cl)(Cl)Cl>>COP(C)(=O)OC.Cl[Sb](Cl)(Cl)(Cl)Cl,,ClCCl,,,,test
US20090221555A1,CC(C)(N)CN.CS(=O)(=O)Cl>>CC(C)(N)CNS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20080194576A1,CCCS.CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(Cl)nc(-c3ccccc3)n2)CC1>>CCCSc1cc(C(=O)N[C@@H](CCC(=O)OC(C)(C)C)C(=O)N2CCN(C(=O)OCC)CC2)nc(-c2ccccc2)n1,,CN(C)C=O,,[H-].[Na+],,test
US20130261116A1,CC1(C)OB(c2ccc(OC3CCOCC3)c(F)c2)OC1(C)C.CNC(=O)c1ccc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)cc1F>>Fc1cc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)ccc1OC1CCOCC1,,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20110065764A1,CCOC(=O)c1noc(-c2ccc(Cl)cc2)c1Cl.NC1CCOCC1>>O=C(NC1CCOCC1)c1noc(-c2ccc(Cl)cc2)c1Cl,,CCO,,,,test
US20150191465A1,C[C@H](N)c1nc2ccn(C)c2cc1C1CCN(C(=O)OC(C)(C)C)C1.Cc1nc(N)nc(Cl)c1C#N>>Cc1nc(N)nc(N[C@@H](C)c2nc3ccn(C)c3cc2[C@@H]2CCN(C(=O)OC(C)(C)C)C2)c1C#N,,CS(C)=O,,CCN(CC)CC,,test
US20100120881A1,COCC(C#N)OS(C)(=O)=O.Cc1cccc(O)c1Cl>>COCC(C#N)Oc1cccc(C)c1Cl,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090203705A1,Nc1ccc(Cl)nn1.OB(O)c1cc(F)cc(F)c1>>Nc1ccc(-c2cc(F)cc(F)c2)nn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20120028953A1,COc1ccc(OC(C)=O)cc1Br>>COc1ccc(O)cc1Br,,CO,O,[K+].[OH-],,test
US20010014740A1,BrBr.CC(=O)N1CCc2c(C)cc(C)cc21>>CC(=O)N1CCc2c1cc(C)c(Br)c2C,,CC(=O)O,,,,test
US08357634B2,CON.O=Cc1cccc(I)c1>>CON=Cc1cccc(I)c1,,CO,,CCN(CC)CC,Cl,test
US20020111494A1,C/C(N)=C/C(=O)OCCC#N.CC(=O)CC(=O)OCc1ccccc1.O=Cc1cccc(Cl)c1>>CC1=C(C(=O)OCCC#N)C(c2cccc(Cl)c2)C(C(=O)OCc2ccccc2)=C(C)N1,,CC(C)O,,,,test
US06692887B1,C1=CC2C3C=CC(C3)C2C1.C=CC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)C1CC2C=CC1C2,,Cc1ccccc1,,,,test
US20100308322A1,Brc1ccc(-c2cc(-c3ccccn3)nc(-c3cccc(-n4c5ccccc5c5cnccc54)n3)c2)cc1.OB(O)c1ccccc1>>c1ccc(-c2ccc(-c3cc(-c4ccccn4)nc(-c4cccc(-n5c6ccccc6c6cnccc65)n4)c3)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,ClC(Cl)Cl,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20090149467A1,Clc1ccnc(Cl)n1.Oc1ccc2[nH]ccc2c1>>Clc1nccc(Oc2ccc3[nH]ccc3c2)n1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20070173506A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@H](CNC(=S)NC(=O)c1ccccc1)Cc1ccc(Cl)cc1>>CC(C)(C)OC(=O)N[C@H](CNC(N)=S)Cc1ccc(Cl)cc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04507498,BrCC1CO1.CCCc1c(OCC(=O)OC)ccc(C(C)=O)c1O>>CCCc1c(OCC(=O)OC)ccc(C(C)=O)c1OCC1CO1,,CC(C)=O,CN(C)C=O,[I-].[K+],,test
US06262040B1,COC(=O)c1ccc2cnn(C3CCCC3)c2c1>>O=C(O)c1ccc2cnn(C3CCCC3)c2c1,,CO,,[Na+].[OH-],,test
US06049006,CC(=O)NCC(O)c1ccccc1>>CC(=O)NCC(=O)c1ccccc1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US05858275,CCCc1ccc(CC[C@@H]2CC[C@@H](CCc3ccccc3)CC2)cc1.O=C(Cl)C(=O)Cl>>CCCc1ccc(CC[C@@H]2CC[C@@H](CCc3ccccc3C(=O)Cl)CC2)cc1,,ClCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20130131044A1,NC1C(O)CC(COCc2ccccc2)C(OCc2ccccc2)C1OCc1ccccc1>>NC1C(O)CC(CO)C(O)C1O,[Pd],CC(=O)O,CO,,,test
US20070197512A1,CC[C@H](C)[C@H](Cl)C(=O)Nc1cc(C)cc(C)c1O>>CC[C@H](C)[C@H]1Oc2c(C)cc(C)cc2NC1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060270646A1,O=S(=O)(c1ccccc1)n1cc(-c2ccccc2)c2cc(-c3ccccc3Oc3ccccc3)cnc21>>c1ccc(Oc2ccccc2-c2cnc3[nH]cc(-c4ccccc4)c3c2)cc1,,CCO,,[Na+].[OH-],,test
US05674876,C=CCN(C(C)=O)c1cc(C)c(OC)c(C)c1Br>>COc1c(C)cc2c(c1C)C(C)CN2C(C)=O,,Cc1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,CCCC[SnH](CCCC)CCCC,test
US20140275071A1,CCCN.Cn1c(=O)n(CCCO[Si](C)(C)C(C)(C)C)c(=O)c2c1nc(Br)n2Cc1ccc(Cl)cc1>>CCCNc1nc2c(c(=O)n(CCCO[Si](C)(C)C(C)(C)C)c(=O)n2C)n1Cc1ccc(Cl)cc1,,CCO,O,,,test
US06251910B1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.CCCSc1nc(N(Cc2ccc(OC)cc2OC)C2CC2c2ccccc2)c2nnn(C3CC(CO)C(O)C3O)c2n1>>CCCSc1nc(N(Cc2ccc(OC)cc2OC)C2CC2c2ccccc2)c2nnn(C3CC(CO[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)C(O)C3O)c2n1,,CN(C)C=O,,O,c1c[nH]cn1,test
US20150299224A1,Cc1nc(Cl)cc(Cl)c1C=O.Nc1ccccc1S>>Cc1nc(Cl)cc(Cl)c1-c1nc2ccccc2s1,,CN(C)C=O,ClCCl,II,,test
US20040092533A1,CC[Si](CC)(CC)OC(C)(C)c1ccn2c(-c3ccnc(Cl)n3)cnc2n1.c1c[nH]cn1>>CC[Si](CC)(CC)OC(C)(C)c1ccn2c(-c3ccnc(-n4ccnc4)n3)cnc2n1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20090163569A1,Cn1cc(C(=O)O)c(C(F)F)n1.O=S(Cl)Cl>>Cn1cc(C(=O)Cl)c(C(F)F)n1,,Clc1ccccc1,,,,test
US20110142796A1,CC(C)(C)OC(=O)N1CCNCC1.O=C(Cl)c1ccc(Cl)nc1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2cccnc2Cl)CC1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CO,test
US05565479,BrBr.O=C(Oc1cccc2c1C(=O)CC2)c1ccccc1>>O=C(Oc1cccc2c1C(=O)C(Br)C2)c1ccccc1,,C1CCOC1,,,,test
US04230635,Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)c1ccccc1,,c1ccncc1,,O,,test
US20090275567A1,C1CCNC1.Cc1ncc(-c2ccnc(NC3CCN(S(=O)(=O)CCCCl)CC3)n2)n1C(C)C>>Cc1ncc(-c2ccnc(NC3CCN(S(=O)(=O)CCCN4CCCC4)CC3)n2)n1C(C)C,,C1CCOC1,,[I-].[Na+],,test
US04639408,Cc1ccc(NS(=O)(=O)c2ccccc2)cc1.O=C(Cl)c1ccccc1>>Cc1ccc(N(C(=O)c2ccccc2)S(=O)(=O)c2ccccc2)cc1,,CO,O,CC#N,CCN(CC)CC,test
US20070299087A1,COc1cc(O)cc(B2OC(C)(C)C(C)(C)O2)c1.CS(=O)(=O)Cl>>COc1cc(OS(C)(=O)=O)cc(B2OC(C)(C)C(C)(C)O2)c1,,ClCCl,,CCN(CC)CC,,test
US20040242636A1,CC(C)(C)OC(=O)NC1CCNCC1.N#Cc1cc(F)cc(F)c1>>CC(C)(C)OC(=O)NC1CCN(c2cc(F)cc(C#N)c2)CC1,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120122888A1,CC(C)C(C#N)C#N.NN>>CC(C)c1c(N)n[nH]c1N,,CCO,,O,,test
US20050059673A1,COc1cc(N2CCNCC2)c2ncccc2c1.COc1cccc2c(CC(C)=O)coc12>>COc1cc(N2CCN(C(C)Cc3coc4c(OC)cccc34)CC2)c2ncccc2c1,,CC(=O)O,ClCCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US06180630B2,O=c1c2n[nH]c3ccccc3c-2nn1-c1ccc(Cl)cc1>>O=c1c2n[nH]c3c(c-2nn1-c1ccc(Cl)cc1)CCCC3,O=[Pt],O=C(O)C(F)(F)F,,[H][H],,test
US04293694,Nc1ccc(F)cc1.O=C1CCCCC1>>Fc1ccc2[nH]c3c(c2c1)CCCC3,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04877779,C1CCOC1.c1ccc(C2SCCCS2)cc1>>C#CCCC1(c2ccccc2)SCCCS1,,C1CCOC1,,[Li]CCCC,,test
US20090099140A1,C=C(CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H](O[Si](C)(C)C(C)(C)C)CCC[C@]12C.C[Si](C)(C)n1ccnc1>>C=C(CCCC(C)(C)O[Si](C)(C)C)[C@H]1CC[C@H]2[C@@H](O[Si](C)(C)C(C)(C)C)CCC[C@]12C,,O,,ClCCl,,test
US20030092770A1,CC(C)S(=O)(=O)Cl.CCCCCC.CN(C)c1ccccn1.C[C@@H](CN)c1ccccc1>>CC(C)S(=O)(=O)NC[C@H](C)c1ccccc1.C[C@@H](CN)c1ccccc1,,CCCCCC,ClCCl,CCN(CC)CC,,test
US20140296208A1,COc1c(N)cc(C(C)(C)C)cc1N.O=S(=O)(Cl)N1CCCCC1>>COc1c(N)cc(C(C)(C)C)cc1NS(=O)(=O)N1CCCCC1,,ClCCl,,c1ccncc1,,test
US20110144136A1,CCCCOc1nc(N)c2nc(OC)n(CC3CCNCC3)c2n1.IC1CCCCC1>>CCCCOc1nc(N)c2[nH]c(=O)n(CC3CCN(C4CCCCC4)CC3)c2n1,,CN(C)C=O,CS(C)=O,CCN(C(C)C)C(C)C,O=C([O-])[O-].[K+].[K+],test
US20130217702A1,N=C(NO)c1[nH]c2ccccc2c1Cl.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c(-c2[nH]c3ccccc3c2Cl)no1,,C1CCOC1,,,,test
US20110166354A1,C[C@@H](O)C(=O)N1CCCC1.O=C(O)Cc1ccccc1Cl.O=S(=O)(Cl)Cl>>C[C@@H](OC(=O)C(Cl)c1ccccc1Cl)C(=O)N1CCCC1,,Cc1ccccc1,O,CCN(CC)CC,O=S(Cl)Cl,test
US04507498,CCCc1c(O)ccc(C(C)=O)c1O.CCCc1c(OCC(=O)OCC)ccc(C(C)=O)c1OCCCCCBr>>CCCc1c(OCCCCCOc2c(C(C)=O)ccc(OCC(=O)OCC)c2CCC)ccc(C(C)=O)c1O,,CC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20060030613A1,CC(C)(C)c1ccc(CNCCc2ccncc2)cc1.O=C(O)c1cc(Cl)cc2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCc2ccncc2)C(=O)c2cc(Cl)cc3cc[nH]c23)cc1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20140213591A1,FC(F)(F)c1cccc(Cl)n1.O=C1CCCc2cc(O)ccc21>>O=C1CCCc2cc(Oc3cccc(C(F)(F)F)n3)ccc21,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20150210630A1,CC(Br)c1ccc(F)cc1.O=C(NCC(=NO)c1ncc(Cl)cc1Cl)c1ccccc1C(F)(F)F>>CC(ON=C(CNC(=O)c1ccccc1C(F)(F)F)c1ncc(Cl)cc1Cl)c1ccc(F)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130252937A1,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(OCCS(C)=O)cc5C)ccc(F)c43)ccc21>>Cc1cc(OCCS(C)=O)cc(C)c1-c1ccc(F)c2c1CC[C@H]2Oc1ccc2c(c1)OC[C@H]2CC(=O)O,,CO,,Cl,[Na+].[OH-],test
US20150252038A1,COC(=O)Cc1cc(Cl)cc(Cl)c1.O=C1CCC(=O)N1Br>>COC(=O)C(Br)c1cc(Cl)cc(Cl)c1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20160046649A1,CNCCOc1ccc(Cl)cc1C(C)(C)C.COC(=O)c1ccccc1N=C=O>>COC(=O)c1ccccc1NC(=O)N(C)CCOc1ccc(Cl)cc1C(C)(C)C,,ClCCl,O,CCN(CC)CC,,test
US20150141387A1,CNCCOc1ccccc1C1(Nc2nccn(-c3cc(C(=O)NC4CC4)cc(F)c3C)c2=O)CC1.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>CNCCOc1ccccc1C1(Nc2nccn(-c3cc(C(=O)NC4CC4)cc(F)c3C)c2=O)CC1.O=C(O)[C@H](O)[C@@H](O)C(=O)O,,CO,,,,test
US20050182085A1,CCOC(=O)c1cc(Nc2c(F)cc(F)cc2Cl)c(Cl)cc1Cl>>O=C(O)c1cc(Nc2c(F)cc(F)cc2Cl)c(Cl)cc1Cl,,CCO,,O=S(=O)(O)O,,test
US20110009394A1,COc1ccc2c(n1)N(CCC(O)COS(=O)(=O)c1ccc(C)cc1)C(=O)CC2>>COc1ccc2c(n1)N(CCC1CO1)C(=O)CC2,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20150011546A1,CI.Cc1c(C(=O)OC(C)(C)C)c2ccccc2n1C(C)C(C)O>>COC(C)C(C)n1c(C)c(C(=O)OC(C)(C)C)c2ccccc21,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20060167107A1,CCCCCCCCCCCCCCCc1cccc(OC)c1C(=O)O.O=S(Cl)Cl>>CCCCCCCCCCCCCCCc1cccc(OC)c1C(=O)Cl,,CCCCCC,,CN(C)C=O,,test
US20050119320A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.OC1CN(C(c2ccccc2)c2ccccc2)C1>>CC(C)(C)[Si](OC1CN(C(c2ccccc2)c2ccccc2)C1)(c1ccccc1)c1ccccc1,,CN(C)C=O,,O,c1c[nH]cn1,test
US05266568,CC(C)=CC(=O)O.SCc1ccccc1>>CC(C)(CC(=O)O)SCc1ccccc1,,C1CCNCC1,,,,test
US20090137595A1,Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1N.Cn1cc(Cl)c(C(=O)O)n1>>Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1NC(=O)c1nn(C)cc1Cl,CN(C)C=O,CC(=O)N(C)C,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US20080312192A1,C1COCCN1.O=[N+]([O-])c1ccc(Br)c(C(F)(F)F)c1>>Nc1ccc(N2CCOCC2)c(C(F)(F)F)c1,[Ni],CCCCCC,CCOC(C)=O,,,test
US20100210466A1,CCc1ccc(-c2ccc(C#C[Si](C)(C)C)cc2)cc1C1C(=O)C(C)(C)OC(C)(C)C1=O>>C#Cc1ccc(-c2ccc(CC)c(C3C(=O)C(C)(C)OC(C)(C)C3=O)c2)cc1,,CO,,O,O=C([O-])[O-].[K+].[K+],test
US20090099172A1,BrC(Br)(Br)Br.CC(C)(C)OC(=O)N1CCN(CCCO)CC1>>CC(C)(C)OC(=O)N1CCN(CCCBr)CC1,,C1CCOC1,CCOC(C)=O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,O=C([O-])[O-].[Na+].[Na+],test
US20120270865A2,CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3cc(F)ccc3c2C)C2CCCCC2)cc1>>Cc1c(C(Nc2ccc(C(=O)N(C)CCC(=O)O)cc2)C2CCCCC2)oc2cc(F)ccc12,,CCO,,C1CCOC1,[Na+].[OH-],test
US20130317231A1,COc1ccc(C2CC(c3cc(OC)c(OC)c(OC)c3)=NN2C(C)=O)cc1OCC(=O)O.Nc1nc2ccc(OC(F)(F)F)cc2s1>>COc1ccc(C2CC(c3cc(OC)c(OC)c(OC)c3)=NN2C(C)=O)cc1OCC(=O)Nc1nc2ccc(OC(F)(F)F)cc2s1,,ClCCl,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20080312280A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CC1(C)CCCN(CCCOc2ccc(I)cc2)C1>>CC1(C)CCCN(CCCOc2ccc(C3(O)CCN(C(=O)OC(C)(C)C)CC3)cc2)C1,,C1CCOC1,,[Li]CCCC,,test
US20070041934A1,NCCCC(O)([PH2]=O)C(CCC(=O)OCc1ccccc1)C(=O)OCc1ccccc1>>NCCCC(O)([PH2]=O)C(CCC(=O)O)C(=O)O,[Pd],CO,O,,,test
US04333759,CC1(C)c2cc(C#N)ccc2OC1O>>CC(C)(CO)c1cc(C#N)ccc1O,,CO,O,[Na+].[OH-],,test
US20120149699A1,CCOC(=O)C(=O)C(C)Br.Nc1ccc(F)cn1>>CCOC(=O)C(=O)C(C)[n+]1cc(F)ccc1N.[Br-],,COCCOC,,,,test
US20030045560A1,CCCCc1c(C(=O)O)c2ccccc2n1C.O=C(Cl)C(=O)Cl>>CCCCc1c(C(=O)Cl)c2ccccc2n1C,,ClCCl,,,,test
US20090233900A1,COC(=O)CC(=O)OC.O=[N+]([O-])c1cc(Cl)c(Cl)c([N+](=O)[O-])c1>>COC(=O)C(C(=O)OC)c1c(Cl)cc([N+](=O)[O-])cc1[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],,test
US09012412B2,C=CCBr.Cc1c(Cc2cc3ccccc3s2)cc(C2OC(CO)CC(O)C2O)c(O)c1C>>C=CCOc1c(C2OC(CO)CC(O)C2O)cc(Cc2cc3ccccc3s2)c(C)c1C,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130281657A1,CC(C)(C)OC(=O)N[C@@H](CCNC(N)=S)C(=O)OC(C)(C)C.O=CC(Br)C=O>>CC(C)(C)OC(=O)N[C@@H](CCNc1ncc(C=O)s1)C(=O)OC(C)(C)C,,C1CCOC1,CC(=O)O,CC(=O)[O-].[Na+],,test
US20020099212A1,COC(=O)c1ccc2nc(C)n(Cc3ccc(N)cc3Cl)c2n1.O=C(Cl)c1ccccc1>>COC(=O)c1ccc2nc(C)n(Cc3ccc(NC(=O)c4ccccc4)cc3Cl)c2n1,,ClCCl,,CCN(CC)CC,O,test
US20140094462A1,C=CCCC(=O)N[C@@H](CN(C)C(=O)[C@H](C)CC=C)c1ccccc1>>C[C@@H]1CC=CCCC(=O)N[C@H](c2ccccc2)CN(C)C1=O,,CCOC(C)=O,Cc1ccccc1,,,test
US20070072813A1,CC(C)I.COc1ccc(Cc2c(O[C@@]3(O)O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)n[nH]c2C)c(F)c1F>>COc1ccc(Cc2c(O[C@@]3(O)O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)nn(C(C)C)c2C)c(F)c1F,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20130274269A1,C[C@H](CN(C[C@@H](O)c1ccsc1)S(=O)(=O)c1ccccc1[N+](=O)[O-])NC(=O)OC(C)(C)C>>C[C@@H](N)CN(C[C@@H](O)c1ccsc1)S(=O)(=O)c1ccccc1[N+](=O)[O-],,ClCCl,,O=C(O)C(F)(F)F,,test
US20090298815A1,CC(C)(C)OC(=O)N1CCN(c2nc(-c3cccc(NS(=O)(=O)c4cc(F)ccc4F)c3F)c(-c3ccnc(Cl)n3)s2)CC1>>O=S(=O)(Nc1cccc(-c2nc(N3CCNCC3)sc2-c2ccnc(Cl)n2)c1F)c1cc(F)ccc1F,,CO,ClCCl,C1COCCO1,Cl,test
US20060199829A1,COC(=O)c1cnc(N2CCc3[nH]c4ccc(-c5ccc(CN6CCN(C)CC6)o5)cc4c3C2)nc1.NO>>CN1CCN(Cc2ccc(-c3ccc4[nH]c5c(c4c3)CN(c3ncc(C(=O)NO)cn3)CC5)o2)CC1,,CO,O,ClCCl,[Na+].[OH-],test
US20130178443A1,CC(C)(C)OC(=O)CNCCC(=O)OCc1cc(F)c(F)cc1-c1ccc2nc(N)nc(C(=O)N3Cc4ccccc4C3)c2c1.Cl.ClCCl>>Cl.Cl.Nc1nc(C(=O)N2Cc3ccccc3C2)c2cc(-c3cc(F)c(F)cc3COC(=O)[C@H](N)CO)ccc2n1,,C1COCCO1,ClCCl,,,test
US20050137212A1,CCOC(=O)C(C)(C)Oc1ccc(CCN(C#N)Cc2ccc(-c3coc(C4CC4)n3)cc2)cc1.NO>>CCOC(=O)C(C)(C)Oc1ccc(CCN(Cc2ccc(-c3coc(C4CC4)n3)cc2)/C(N)=N/O)cc1,,CN(C)C=O,,Cl,CC(=O)[O-].[Na+],test
US20060257987A1,COC(=O)CCc1ccc(OCCC(C)OS(C)(=O)=O)cc1C.Oc1ccc(C(F)(F)F)cc1-c1ccccn1>>COC(=O)CCc1ccc(OCCC(C)Oc2ccc(C(F)(F)F)cc2-c2ccccn2)cc1C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080119555A1,O=[N+]([O-])c1ccccc1-c1ccc(S(=O)(=O)NCCCCO)cc1>>Nc1ccccc1-c1ccc(S(=O)(=O)NCCCCO)cc1,[Pd],CO,,,,test
US20090099187A1,COc1ccc(S(=O)(=O)Cl)c2c1CC(NC(=O)C(F)(F)F)CC2.Oc1ccc(Cl)c(Cl)c1>>COc1ccc(S(=O)(=O)Oc2ccc(Cl)c(Cl)c2)c2c1CC(NC(=O)C(F)(F)F)CC2,,ClCCl,,c1ccncc1,,test
US20150344480A1,Fc1ccc(-c2cc[nH]n2)cc1.O=C1CCC(=O)N1Br>>Fc1ccc(-c2n[nH]cc2Br)cc1,,CN(C)C=O,,,,test
US20160039783A1,CCOC(=O)C(OC(C)(C)C)c1c(C)sc(-c2ccncc2)c1-c1ccc2c(c1)CCCO2.O=[Se]=O>>CCOC(=O)C(OC(C)(C)C)c1c(C=O)sc(-c2ccncc2)c1-c1ccc2c(c1)CCCO2,,C1COCCO1,CCOC(C)=O,,,test
US20120130069A1,CCOC(=O)c1n[nH]c2cc(-c3cccc(N)c3)ccc12.O=S(=O)(Cl)c1cccc(C(F)(F)F)c1>>CCOC(=O)c1n[nH]c2cc(-c3cccc(NS(=O)(=O)c4cccc(C(F)(F)F)c4)c3)ccc12,,c1ccncc1,,,,test
US20090143353A1,CN(C)[C@H]1CCNC1.Cc1c(-c2ccccc2)c(F)c2oc(-c3cccn3C)nc2c1C#N>>Cc1c(-c2ccccc2)c(N2CC[C@H](N(C)C)C2)c2oc(-c3cccn3C)nc2c1C#N,,CS(C)=O,,CCN(CC)CC,,test
US20120134934A1,CC#N.CC(C)(C)OC(=O)NC(C(=O)O[C@H]1CN2CCC1CC2)c1ccc(F)cc1.CCOC(C)=O.O=C(CBr)c1ccccc1>>CC(C)(C)OC(=O)NC(C(=O)O[C@H]1C[N+]2(CC(=O)c3ccccc3)CCC1CC2)c1ccc(F)cc1.CC(C)OC(C)C.[Br-],,CC#N,CCOC(C)=O,,,test
US20070213358A1,CC=C(C)[Mg]Br.O=[N+]([O-])c1cnccc1OCc1ccc(F)cc1>>Cc1[nH]c2c(OCc3ccc(F)cc3)ccnc2c1C,,C1CCOC1,,[Cl-].[NH4+],,test
US06350749B1,NC1CCCCC1O.O=C1CC(=O)CC(c2ccccc2)C1>>O=C1CC(c2ccccc2)Cc2[nH]c3c(c21)CCCC3,,C1CCOC1,,,,test
US20120142717A1,N#CN.OCCc1ccc(Oc2c(F)cc(Cl)cc2F)cc1>>N=C(N)OCCc1ccc(Oc2c(F)cc(Cl)cc2F)cc1,,C1CCOC1,,O=S(=O)(O)C(F)(F)F,,test
US20100317675A1,Cl.O=C(Nc1ccccc1)c1cn2cc(-c3cc(CO)ccn3)ccc2n1>>Cl.O=C(Nc1ccccc1)c1cn2cc(-c3cc(CO)ccn3)ccc2n1,,CO,,,,test
US04267176,CCOC(=O)Cc1nc(Cl)cc(NC=O)n1>>CCOC(=O)Cc1nccc(NC=O)n1,[Pd],CCO,,CC(=O)[O-].[Na+],,test
US05541210,Cc1ccc(F)cc1[N+](=O)[O-].O=[N+]([O-])O>>Cc1ccc(F)c([N+](=O)[O-])c1[N+](=O)[O-],,O=S(=O)(O)O,,,,test
US20160169864A1,CCCCCCCCCCCCCCCCCC(=O)O.COc1cc(C=O)c([N+](=O)[O-])cc1OCCBr>>CCCCCCCCCCCCCCCCCC(=O)OCCOc1cc([N+](=O)[O-])c(C=O)cc1OC,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US03935214,ClCCN1CCCCC1.Clc1ccc(CN2CCNCC2c2ccccc2)cc1>>Clc1ccc(CN2CCN(CCN3CCCCC3)CC2c2ccccc2)cc1,,CC(C)=O,,CCN(CC)CC,,test
US20100324343A1,O=C(Cl)CCl.Oc1ccccc1O>>O=C(CCl)c1ccc(O)c(O)c1,,O,,O=P(Cl)(Cl)Cl,,test
US05733913,CCCS(=O)(=O)Cl.Nc1ncc2cc(-c3c(Cl)cccc3Cl)c(N)nc2n1>>CCCS(=O)(=O)Nc1nc2nc(N)ncc2cc1-c1c(Cl)cccc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20150111885A1,Cn1ccc2c(c1=O)CCC2.O=C1CCC(=O)N1Br>>Cn1cc(Br)c2c(c1=O)CCC2,,CC#N,,,,test
US20070219230A1,CCC(=O)CC.NNc1cccnc1Cl>>CCC(CC)=NNc1cccnc1Cl,,CCO,,,,test
US20120010281A1,C=CC[C@@]12CCC[C@@H]([C@H](O)CC(=C)C)[C@@H]1C1(CC2)OCCO1>>C=CC[C@@]12CCC[C@@H](C(=O)CC(=C)C)[C@@H]1C1(CC2)OCCO1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US20070287725A1,CCc1nc2c(Cl)nc3ccccc3c2n1Cc1cc(-c2ccc(F)cc2)no1.N>>CCc1nc2c(N)nc3ccccc3c2n1Cc1cc(-c2ccc(F)cc2)no1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,ClCCl,,,test
US20160194358A1,CC(NC(=O)OC(C)(C)C)[C@H](O)c1ncco1>>C[C@H](NC(=O)OC(C)(C)C)C(=O)c1ncco1,,CCOC(C)=O,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20140371239A1,Fc1cccc([Mg]Br)c1.N#Cc1ccc(O)cc1.O=C(c1ccccn1)C1CCN(CCCCl)CC1>>N#Cc1ccc(OCCCN2CCC(C(O)(c3cccc(F)c3)c3ccccn3)CC2)cc1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20100022598A1,C=Cc1[nH]c(CC(O)(c2ccc(-c3ccc(F)cn3)cc2)C(F)(F)F)nc1CC(C)(C)C>>CCc1[nH]c(CC(O)(c2ccc(-c3ccc(F)cn3)cc2)C(F)(F)F)nc1CC(C)(C)C,[Pd],CO,,,,test
US04547503,C1CNCCN1.O=C(O)c1cn(C2CC2)c2cc(Cl)c(F)cc2c1=O>>O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O,,CS(C)=O,,,,test
US20150087646A1,COC(=O)c1ccc(CBr)cc1OC.C[N+](=O)[O-]>>COC(=O)c1ccc(C=O)cc1OC,,CO,,C[O-].[Na+],,test
US20100152192A1,CCOC(=O)C(Cl)C(C)=O.Nc1nccs1>>CCOC(=O)c1c(C)nc2sccn12,,CCO,,,,test
US20090186373A1,Nc1nccc(Cl)n1.O=C(NCc1ccc(CO)cc1)C(F)(F)F>>Nc1nccc(OCc2ccc(CNC(=O)C(F)(F)F)cc2)n1,,CC(=O)N(C)C,,O,[H-].[Na+],test
US06124323,Nc1ccc(OCCCN2CCC(Cc3ccccc3)CC2)cc1[N+](=O)[O-]>>Nc1ccc(OCCCN2CCC(Cc3ccccc3)CC2)cc1N,,CCO,,,,test
US20100298299A1,COC(=O)[C@@H](C)NC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccccc2)cc1>>C[C@@H](NC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccccc2)cc1)C(=O)O,,C1CCOC1,,CO,O,test
US20110112062A1,NC1C2CC3CC(C2)CC1C3.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(NC1C2CC3CC(C2)CC1C3)Oc1ccc([N+](=O)[O-])cc1,,CC#N,,Cl,O=C([O-])O.[Na+],test
US20070249670A1,Nc1cc2ccccc2cc1C(=O)O.O=C(CNCC1CCCCC1)OCc1ccccc1>>Nc1cc2ccccc2cc1C(=O)N(CC(=O)OCc1ccccc1)CC1CCCCC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120220453A1,O=C1CCC(=O)N1Br.c1cncc(-n2cccn2)c1>>Brc1cnn(-c2cccnc2)c1,,CC#N,CCOC(C)=O,,,test
US20100022531A1,O=C(Cl)c1ccccc1.OC(CNc1ncnc2c1CCNC2)C12CC3CC(CC(C3)C1)C2>>O=C(c1ccccc1)N1CCc2c(ncnc2NCC(O)C23CC4CC(CC(C4)C2)C3)C1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,,test
US05133965,NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O>>NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O,,O,,O=S(=O)(O)O,,test
US20110306631A1,COC(=O)c1cc(Cl)c2c(C)cc3cccnc3c2n1>>Cc1cc2cccnc2c2nc(CO)cc(Cl)c12,,CO,ClCCl,O,[BH4-].[Na+],test
US20110251223A1,CC(C)(C)OC(=O)N[C@@H]1c2cccnc2C(=O)CC[C@H]1c1cccc(F)c1F.CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)/C=C1\CC[C@@H](c2cccc(F)c2F)[C@H](NC(=O)OC(C)(C)C)c2cccnc21,,Cc1ccccc1,,,,test
US20040033995A1,BrCc1ccccc1.CC(C)(C)OC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@H](Cc1cn(Cc2ccccc2)c2ccccc12)C(=O)OCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20140142307A1,Br.BrCCc1cccc2ccccc12.Clc1nc[nH]c1Cl.O=C(O)CCCCCBr>>O=C(O)CCCCCn1c[n+](CCc2cccc3ccccc23)c(Cl)c1Cl.[Br-],,CC#N,,[K+].[OH-],,test
US06262044B1,CC(C)(C)OC(=O)c1c(N)sc2c1CC(CN)OC2.COc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc(S(=O)(=O)NCC2Cc3c(sc(N)c3C(=O)OC(C)(C)C)CO2)cc1,,ClCCl,,c1ccncc1,,test
US20010041700A1,CC(C)(C)CC=O.OC1CCNC1>>CC(C)(C)CCN1CCC(O)C1,,C1CCOC1,CC(=O)O,[Na+].[OH-],,test
US05985905,CN1CCC(Br)C1=O.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CN1CCC([P+](c2ccccc2)(c2ccccc2)c2ccccc2)C1=O.[Br-],,C1CCOC1,,,,test
US20080207666A1,O=C(CC(O)c1cccc(F)c1)C1C=C(c2ccc(Cl)cc2)C(c2ccccc2Cl)=NC1=O>>O=C1CC(c2cccc(F)c2)Oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc21,,CCOC(C)=O,Cc1ccccc1,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090143440A1,Nc1ccc(Cl)cn1.O=C(O)c1cc(Cl)[nH]n1>>O=C(Nc1ccc(Cl)cn1)c1cc(Cl)[nH]n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20100035865A1,CC(C)S(=O)(=O)N[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1c1ccc(I)cc1.OB(O)c1ccccc1>>CC(C)S(=O)(=O)N[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1c1ccc(-c2ccccc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20130338066A1,CC1(C)OC(N[C@@H](CCO[Si](C)(C)C(C)(C)C)c2ccccc2)=NS(=O)(=O)C1c1cccc(O)c1>>CC1(C)OC(N[C@@H](CCO)c2ccccc2)=NS(=O)(=O)C1c1cccc(O)c1,,CO,,Cl,,test
US20060258719A1,ClP(Cl)(Cl)(Cl)Cl.Nc1nonc1C(=O)Nc1cccc(Cl)n1>>Nc1nonc1C(Cl)=Nc1cccc(Cl)n1,,c1ccccc1,,,,test
US04450169,CC1(C)[C@@H](C=C2CCCC2)[C@H]1C(=O)Cl.OCc1cnc(Oc2ccccc2)s1>>CC1(C)[C@@H](C=C2CCCC2)[C@H]1C(=O)OCc1cnc(Oc2ccccc2)s1,,c1ccccc1,,Cl,c1ccncc1,test
US20060063762A1,CCN(CC)C(=O)COc1cccc2c(C[C@@H](C)N)c[nH]c12.c1cncc([C@@H]2CO2)c1>>CCN(CC)C(=O)COc1cccc2c(C[C@@H](C)NC[C@H](O)c3cccnc3)c[nH]c12,,CCO,O,,,test
US20070112068A1,BrCBr.N#CC(C#N)CCC(F)(F)F>>N#CC(C#N)(CBr)CCC(F)(F)F,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20150259359A1,CS(=O)(=O)Cl.C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)[C@@H](CO)CN1C(=O)OC(C)(C)C>>C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)[C@@H](CCl)CN1C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20090312328A1,COc1ccc(CN)cc1.Cc1ccc(S(=O)(=O)N(CC(=O)O)c2cccc(Cl)c2C)cc1>>COc1ccc(CNC(=O)CN(c2cccc(Cl)c2C)S(=O)(=O)c2ccc(C)cc2)cc1,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20120270893A1,CC(C)(C)NN.CN(C)C=C1CC2(C=CC1=O)CCN(C(=O)OCc1ccccc1)CC2>>CC(C)(C)n1ncc2c1C=CC1(CCN(C(=O)OCc3ccccc3)CC1)C2,,CCO,,CC(=O)O,Cl,test
US05204473,CC(=O)NC1CC(C)(C)N(OC2CCCCC2)C(C)(C)C1>>CC1(C)CC(N)CC(C)(C)N1OC1CCCCC1,,Cl,O,,,test
US20120245144A1,CC(=O)Cl.Cc1nc(-c2cn3c(n2)-c2ccc(OC(C4CCN(C(=O)OCc5ccccc5)CC4)C(F)(F)F)cc2OCC3)n(C(C)C)n1>>CC(=O)N1CCC(C(Oc2ccc3c(c2)OCCn2cc(-c4nc(C)nn4C(C)C)nc2-3)C(F)(F)F)CC1,[Pd],CC(C)=O,,CCN(C(C)C)C(C)C,CO,test
US20160159752A1,CC(C)(C)[Si](C)(C)Cl.OCCC[C@H]1CN(Cc2ccccc2)CCN1>>CC(C)(C)[Si](C)(C)OCCC[C@H]1CN(Cc2ccccc2)CCN1,,ClCCl,,c1c[nH]cn1,,test
US20120101099A1,COC(=O)C=Cc1ccc(Cn2cc(-c3ccc(CN4CCCC4)cc3)nn2)cc1>>O=C(O)C=Cc1ccc(Cn2cc(-c3ccc(CN4CCCC4)cc3)nn2)cc1,,CO,ClC(Cl)Cl,O,[Na+].[OH-],test
US20160130226A1,COc1ccccc1-c1cccc(B(O)O)c1>>OB(O)c1cccc(-c2ccccc2O)c1,,ClCCl,,BrB(Br)Br,CO,test
US20110136801A1,COCCc1nc2c(N)nc3ccccc3c2n1CCCCN.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>COCCc1nc2c(N)nc3ccccc3c2n1CCCCNS(=O)(=O)c1ccccc1[N+](=O)[O-],,C1CCOC1,ClC(Cl)Cl,,,test
US20030149004A1,CC1CC(=O)OC(=O)C1.O=C(O)CN1CCCC1N1CCNCC1>>CN1CCN(C(=O)CCCC(=O)O)CC1,,C1COCCO1,,,,test
US20120316161A1,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1Cl.OB(O)c1ccc(C(F)(F)F)cc1>>CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc(C(F)(F)F)cc1,,COCCOC,O,CCN(C(C)C)C(C)C,,test
US20030176418A1,CCCCC1CCNCC1.CCc1c(Cl)cc2c(c1Cl)OCC(=O)N2CCCCl>>CCCCC1CCN(CCCN2C(=O)COc3c2cc(Cl)c(CC)c3Cl)CC1,,CO,ClCCl,[I-].[K+],O=C([O-])O.[Na+],test
US20020037888A1,COC1=CC=CC(C)(C2CCCCC(=O)N2)C1>>CC1(C2CCCCC(=O)N2)C=CC=C(O)C1,,ClC(Cl)Cl,,BrB(Br)Br,,test
US20100298306A1,CCOC(=O)C(=O)OCC.COc1cccc2c1OCCC2=O>>CCOC(=O)C(=O)C1COc2c(OC)cccc2C1=O,,C1CCOC1,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20140045862A1,COc1ccc(CN(c2ccncn2)S(=O)(=O)c2ccc(O[C@H]3CCC[C@@H]3c3ccnn3C)c(C(F)(F)F)c2)c(OC)c1>>Cn1nccc1[C@H]1CCC[C@@H]1Oc1ccc(S(=O)(=O)Nc2ccncn2)cc1C(F)(F)F,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US05616599,CCOC(=O)c1c(C(C)(C)O)nc(CC)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCOC(=O)c1c(C(C)(C)O)nc(CC)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,O,,CC(=O)O,,test
US20130190288A1,CC(=O)N1CCN(c2ccc(C=O)cc2)CC1.NC1CCC1>>CC(=O)N1CCN(c2ccc(CNC3CCC3)cc2)CC1,,CC(Cl)Cl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20040092520A1,CCNC1(C#N)CN(C(c2ccccc2)c2ccccc2)C1.O=S(=O)(O)O>>CCNC1(C(N)=O)CN(C(c2ccccc2)c2ccccc2)C1,,CCOC(C)=O,ClCCl,,,test
US20070197478A1,O=[N+]([O-])c1c(NCc2ccccc2)cc(C(F)(F)F)nc1Cl>>Nc1c(NCc2ccccc2)cc(C(F)(F)F)nc1Cl,[Fe],CC(=O)O,O,,,test
US20060116400A1,O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(-c2ccc(C3=NOC(CO)C3)[n+]([O-])c2)c(F)c1.O=S1(=O)CCC(O)(C2CC(c3ccc(Br)cn3)=NO2)C1>>O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(-c2ccc(C3=NOC(C4(O)CCS(=O)(=O)C4)C3)nc2)c(F)c1,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20060229280A1,CCCCNOCCC.O=C(Br)CBr>>CCCCN(OCCC)C(=O)CBr,,CC#N,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20110294822A1,CC[C@@H](O)c1ccccc1NC(=O)C(F)(F)F.Cl>>CC[C@@H](O)c1ccccc1N.Cl,,CC(C)O,,,,test
US20080306045A1,CC(C)(C)OC(=O)N1CCCc2ccc([N+](=O)[O-])cc2C1>>CC(C)(C)OC(=O)N1CCCc2ccc(N)cc2C1,[Pd],CCO,,,,test
US20140005188A1,CC(C)(C)OC(=O)N1CCC[C@@](F)(CN)C1.Clc1cc2nccnc2c(Cl)n1>>CC(C)(C)OC(=O)N1CCC[C@@](F)(CNc2nc(Cl)cc3nccnc23)C1,,CN1CCCC1=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20110281795A1,CCOC(C)=O.CN(C)C=O.COC(CBr)OC.Sc1ccc(Cl)cc1Br>>CCOC(CSc1ccc(Cl)cc1Br)OCC,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05366972,CCNc1ncccc1NC(=O)c1cc([N+](=O)[O-])cnc1Cl>>CCN1c2ncccc2NC(=O)c2cc([N+](=O)[O-])cnc21,,Cc1ccccc1C,,,,test
US03971819,COCCNc1c([N+](=O)[O-])cc(C(=O)O)cc1S(N)(=O)=O>>COCCNc1c(N)cc(C(=O)O)cc1S(N)(=O)=O,[Ni],[Na+],[OH-],[H][H],,test
US20140045872A1,Cc1ccncc1I.O=C1NCCc2ccc3ncsc3c21>>Cc1ccncc1N1CCc2ccc3ncsc3c2C1=O,I[Cu]I,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20120309738A1,Cn1c(Nc2c(Cl)ccc(CNC(=O)OC(C)(C)C)c2Cl)nc2cc(Cl)c(N3CCCC(C(F)(F)F)C3)cc21>>Cn1c(Nc2c(Cl)ccc(CN)c2Cl)nc2cc(Cl)c(N3CCCC(C(F)(F)F)C3)cc21,,C1COCCO1,,Cl,,test
US20160257682A1,CC(C)n1nc(N2CC(C(=O)O)C2)c2cnc(Cl)cc21.COCCN>>COCCNC(=O)C1CN(c2nn(C(C)C)c3cc(Cl)ncc23)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20070037794A1,CC(C)(C)c1ccc(S(=O)(=O)Nc2cc(Cl)cnc2C(=O)O)cc1.CNc1ccccc1F>>CN(C(=O)c1ncc(Cl)cc1NS(=O)(=O)c1ccc(C(C)(C)C)cc1)c1ccccc1F,,CN1CCCC1=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US04399141,C=C1c2ccc(OC)cc2CC(=O)c2ccccc21.NO>>C=C1c2ccc(OC)cc2CC(=NO)c2ccccc21,,CO,,Cl,CC(=O)[O-].[Na+],test
US20030220393A1,CCCCC1OC(=O)c2cc(N)ccc21.O=C(O)C(O)C(O)C(=O)O>>CCCC[C@H]1OC(=O)c2cc(N)ccc21.O=C(O)C(O)C(O)C(=O)O,,CO,,,,test
US04256760,CC(=O)C1(O)C=CC=CC1C(=O)O.O=C1OC(Br)c2ccccc21>>CC(=O)C1(O)C=CC=CC1C(=O)OC1OC(=O)c2ccccc21,,CC(C)=O,,CCN(CC)CC,,test
US04066772,Cc1ccc(NCCCO)c(N)c1.N#C[O-]>>Cc1ccc2c(c1)[nH]c(=O)n2CCCO,,O,,Cl,,test
US20160159815A1,COc1nc(C(=O)N2CC[C@]3(c4cccc(F)c4)OCO[C@@H]3C2)ccc1OCC1C2CC(O)CC12>>COc1nc(C(=O)N2CC[C@]3(c4cccc(F)c4)OCO[C@@H]3C2)ccc1OCC1C2CC(=O)CC12,,ClCCl,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20160207883A1,CC(=O)c1ccc(C(=O)O)cc1Br.CI>>COC(=O)c1ccc(C(C)=O)c(Br)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150274704A1,CC(=O)OC(C)=O.Clc1cnc(Nc2cc(C3CC3)[nH]n2)nc1NC1CC2CNCC2C1>>CC(=O)N1CC2CC(Nc3nc(Nc4cc(C5CC5)[nH]n4)ncc3Cl)CC2C1,,ClCCl,,CCN(CC)CC,,test
US20080292626A1,CC(C)(C)OC(=O)NCC=O.Cc1csc(Cn2c([C@H](N)C(C)C)nc3c(oc4ccc(F)cc43)c2=O)c1>>Cc1csc(Cn2c([C@H](NCCNC(=O)OC(C)(C)C)C(C)C)nc3c(oc4ccc(F)cc43)c2=O)c1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20080188463A1,COC(=O)C(O)(CC(C)C)C(=O)N[C@@H]1C(=O)Nc2ccccc2-c2ccccc21>>CC(C)CC(O)(C(=O)O)C(=O)N[C@@H]1C(=O)Nc2ccccc2-c2ccccc21,,C1CCOC1,O,[Li+].[OH-],,test
US20150238471A1,Cc1nc(Nc2ccc(Br)cc2)c(C)c(C)c1OCc1ccccc1>>Br.Cc1nc(Nc2ccccc2)c(C)c(C)c1O,[Pd],C1CCOC1,,CO,,test
US20100152441A1,CS(=O)(=O)c1ccc(O)c(N)c1.O=C(Br)CBr>>CS(=O)(=O)c1ccc2c(c1)NC(=O)CO2,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US04126689,CCOC(=O)N1CCC(Nc2ccc(Cl)cc2)CC1.O=C(Cl)Cc1ccccc1>>CCOC(=O)N1CCC(N(C(=O)Cc2ccccc2)c2ccc(Cl)cc2)CC1,,c1ccccc1,,,,test
US04997650,CCOc1ccc(C(C)(C)COCc2cccc(Oc3ccccc3)c2)cc1Cl.CN1CCN(C)C1=O>>CC(C)COCC(C)C,,O,,Cl,[K+].[OH-],test
US20090048326A1,CCCC[Sn](CCCC)(CCCC)c1ccco1.CCCN1C[C@@H]2C[C@@H](c3ccc(NS(=O)(=O)c4ccc(Br)cc4)cc3)[C@@H]2C1>>CCCN1C[C@@H]2C[C@@H](c3ccc(NS(=O)(=O)c4ccc(-c5ccco5)cc4)cc3)[C@@H]2C1,,C1CCOC1,,,,test
US05011932,CNN=C(C)c1ccncc1.O=C(Cl)c1ccccc1>>CC(=NN(C)C(=O)c1ccccc1)c1ccncc1,,c1ccncc1,,,,test
US20140114068A1,Cc1cc2c(cc1C)C1(N)C(=O)c3ccccc3C1(O)O2.O=C(O)c1ccc[nH]1>>Cc1cc2c(cc1C)C1(NC(=O)c3ccc[nH]3)C(=O)c3ccccc3C1(O)O2,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20150045354A1,CC1(C)OB(c2ccc(CN3CCOCC3)cc2)OC1(C)C.O=C(NCCN1CCCC1)c1cc(Cl)nc2ccccc12>>O=C(NCCN1CCCC1)c1cc(-c2ccc(CN3CCOCC3)cc2)nc2ccccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140100108A1,CCn1cc(C#N)c(N)n1.Cl[Cu]>>CCn1cc(C#N)c(Cl)n1,Cl[Cu],Cl,,O=N[O-].[Na+],,test
US20120088748A1,CC(C)(C)OC(=O)N1CCO[C@@H](CI)[C@H](c2ccc(Cl)c(Cl)c2)C1.O=c1cccc[nH]1>>CC(C)(C)OC(=O)N1CCO[C@@H](Cn2ccccc2=O)[C@H](c2ccc(Cl)c(Cl)c2)C1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20140107126A1,CC(=O)Nc1sc(Br)nc1Br>>CC(=O)Nc1scnc1Br,[Ni],CCO,,CCNCC,,test
US20030207889A1,C=[N+]=[N-].O=C(O)C(CBr)CCCc1ccccc1>>COC(=O)C(CBr)CCCc1ccccc1,,CCOCC,,,,test
US20160176882A1,BrCCBr.Oc1cncc(Br)c1>>BrCCOc1cncc(Br)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20060173018A1,CC(=O)C[C@@H](O)C(=O)N1CCN(C(=O)OCc2ccccc2)CC1.Cc1ccc2c(Cl)nc(-c3ccccc3O)nc2c1>>CC(=O)C[C@@H](O)C(=O)N1CCN(c2nc(-c3ccccc3O)nc3cc(C)ccc23)CC1,[Pd],CO,,CCN(CC)CC,,test
US20100216836A1,BrCC1COc2ccccc2O1.CCOC(=O)C1CCCNC1>>CCOC(=O)C1CCCN(CC2COc3ccccc3O2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20070244125A1,C1CCN(C2CCNCC2)CC1.CCOC(=O)c1cc2cc(C(=O)O)ccc2[nH]1>>CCOC(=O)c1cc2cc(C(=O)N3CCC(N4CCCCC4)CC3)ccc2[nH]1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20040157885A1,CCOC(=O)C(C)(C)Br.Cc1ccc(C2CCCN(C(=O)OCc3ccccc3)C2)cc1O>>CCOC(=O)C(C)(C)Oc1cc(C2CCCN(C(=O)OCc3ccccc3)C2)ccc1C,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100234395A1,CNO.COc1ccc(-c2nc(C3CCNCC3)sc2-c2ccc(C)cc2)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc(-c2nc(C3CCN(C(=O)N(C)O)CC3)sc2-c2ccc(C)cc2)cc1,,C1CCOC1,,CCN(CC)CC,Cl,test
US20130210880A1,O=C1NC(Cc2ccccc2)c2cc(O)ccc21.O=S(=O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>O=C1NC(Cc2ccccc2)c2cc(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)ccc21,,ClCCl,,CCN(CC)CC,,test
US20040204584A1,COc1ccc(C(=O)O)cc1OC.COc1ccc(C2COCCO2)c2sc(N)nc12>>COc1ccc(C(=O)Nc2nc3c(OC)ccc(C4COCCO4)c3s2)cc1OC,,C1CCOC1,ClC(Cl)Cl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030229066A1,COC(=O)c1sc2c(C(F)(F)F)cccc2c1C1CCN(C(C)=O)CC1>>CC(=O)N1CCC(c2c(C(=O)O)sc3c(C(F)(F)F)cccc23)CC1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20160200674A1,Cc1c(Br)cc(N)cc1Br.O=C(Cl)Cl>>Cc1c(Br)cc(N=C=O)cc1Br,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US05767293,C1CCNCC1.COC1C(O)CCC2(CO2)C1C1(C)OC1CC=C(C)C.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>COC1C(OC(=O)N2CCCCC2)CCC2(CO2)C1C1(C)OC1CC=C(C)C,CN(C)c1ccncc1,CCOCC,ClCCl,c1ccncc1,,test
US06884868B1,COC1(c2ccccc2)CCN(c2ccc(N3CCN(C(C)=O)CC3)cc2)CC1>>COC1(c2ccccc2)CCN(c2ccc(N3CCNCC3)cc2)CC1,,CCO,,[Na+].[OH-],,test
US20050182093A1,Cc1c(-c2ccccc2)nc2ccccc2c1C(=O)O.ClCCl>>COC(=O)c1c(C)c(-c2ccccc2)nc2ccccc12,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US05302700,CI.COc1ccc(C=O)c(O)c1I>>COc1ccc(C=O)c(OC)c1I,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100087427A1,CC(C)(C)OC(=O)N1C[C@H](CNc2ccc(Cl)cc2)[C@@H](Cc2ccccc2)C1.N#Cc1ccc(CBr)cc1>>N#Cc1ccc(CN(C[C@H]2CNC[C@@H]2Cc2ccccc2)c2ccc(Cl)cc2)cc1,,O,,CC#N,CC#N,test
US04927845,BrBr.O=C1c2c(O)cccc2Cc2cccc(O)c21>>O=C1c2c(O)cccc2C(Br)c2cccc(O)c21,,S=C=S,,,,test
US05166214,CCCCCCCN(CCCCCSc1nc(-c2ccc(OC)cc2)c(-c2ccc(OC)cc2)[nH]1)C(=O)Cc1ccc(F)cc1F>>CCCCCCCN(CCCCCSc1nc(-c2ccc(OC)cc2)c(-c2ccc(OC)cc2)[nH]1)CCc1ccc(F)cc1F,,C1CCOC1,,[H-].[Na+],,test
US20070027155A1,CI.Cc1cc(O)cnc1N1CCN(c2cc(-c3ccc(F)c(Cl)c3)nc(N3CCCC3C)n2)CC1>>COc1cnc(N2CCN(c3cc(-c4ccc(F)c(Cl)c4)nc(N4CCCC4C)n3)CC2)c(C)c1,,CN(C)C=O,,[H-].[Na+],,test
US05470845,II.OCCCCCCc1ccccc1-c1ccccc1>>ICCCCCCc1ccc(-c2ccccc2)cc1,,C1CCOC1,CCOCC,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060148779A1,CC(C)(C)OC(=O)CBr.Cc1cc(C)c2oc(=O)[nH]c2c1>>Cc1cc(C)c2oc(=O)n(CC(=O)OC(C)(C)C)c2c1,,CN(C)C=O,,[H-].[Na+],,test
US20090170920A1,C=COCCONC(=O)C[C@H]1NC(=O)N([C@H](c2ncc(-c3ccc(I)cc3)[nH]2)[C@@H](C)c2ccccc2)C1=O>>C[C@@H](c1ccccc1)[C@@H](c1ncc(-c2ccc(I)cc2)[nH]1)N1C(=O)N[C@H](CC(=O)NOCCO)C1=O,,CO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20100184815A1,CCCn1c([C@H](C)OCc2ccccc2)nn(Cc2ccc(C)cc2)c1=O>>CCCn1c([C@H](C)O)nn(Cc2ccc(C)cc2)c1=O,[Pd],CCO,,CC(=O)O,,test
US04554283,CON(C)C(=O)NNc1cccc2c1OC(C)C2.O=C(Cl)Cl>>CON(C)C(=O)NN(C(=O)Cl)c1cccc2c1OC(C)C2,,c1ccccc1,,,,test
US03932411,Cc1ccc(N2CCN(CCCCl)CC2)cc1.O=C1CCCc2c(O)cccc21>>Cc1ccc(N2CCN(CCCOc3cccc4c3CCCC4=O)CC2)cc1.Cl,,CC(C)O,,[K+].[OH-],,test
US20110275797A1,COC(=O)c1cc(-c2cnco2)ccc1OCc1ccccc1>>O=C(O)c1cc(-c2cnco2)ccc1OCc1ccccc1,,C1COCCO1,,[Na+].[OH-],,test
US20160016948A1,CC(O)[C@H](C)N.O=[N+]([O-])c1cnc(Br)cc1Br>>CC(O)[C@H](C)Nc1cc(Br)ncc1[N+](=O)[O-],,C1CCOC1,O,CCN(CC)CC,Cl,test
US20130338140A1,CC(C)(C)OC(=O)N[C@H](CCS(C)(=O)=O)c1ccc(Cl)c(Cl)c1.Cl>>CS(=O)(=O)CC[C@@H](N)c1ccc(Cl)c(Cl)c1.Cl,,CCOCC,ClCCl,C1COCCO1,,test
US20040122057A1,CCOC(C(=O)NCc1ccc(C#N)cc1)c1c(F)cc(-c2ccccc2C=O)cc1F>>CCOC(C(=O)NCc1ccc(C#N)cc1)c1c(F)cc(-c2ccccc2CO)cc1F,,CCO,,[BH4-].[Na+],,test
US20080261973A1,CS(=O)(=O)Nc1cccc(Nc2nc(N)cc(O)n2)c1.O=CCCl>>CS(=O)(=O)Nc1cccc(Nc2nc3[nH]ccc3c(=O)[nH]2)c1,,CC#N,O,CC(=O)[O-].[Na+],,test
US05114939,CC(=O)N(CCc1ccccc1)c1ccnc2ccccc12>>CCN(CCc1ccccc1)c1ccnc2ccccc12,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040116732A1,CNN.COC(OC)C(C#N)=NO.N>>Cn1ncc(N=O)c1N,,CO,O,Cl,,test
US04937235,CC(=O)O.O=C1[C@@H](O)CCN1CC#CCN1CCCC1>>CC(=O)O[C@@H]1CCN(CC#CCN2CCCC2)C1=O,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030130512A1,CC1(C)OCC(CCn2cnc3cnc(N)nc32)CO1.Cl>>Cl.Nc1ncc2ncn(CCC(CO)CO)c2n1,,C1CCOC1,CO,,,test
US20160108027A1,CC1OC[C@H](CCO)N(Cc2ccccc2)C1=O>>CC1CN(Cc2ccccc2)[C@@H](CCO)CO1,,C1CCOC1,,CO,,test
US20010027196A1,CS(=O)c1nc(N)nc(-c2ccco2)c1C#N.NCc1ccc(C(F)(F)F)cc1>>N#Cc1c(NCc2ccc(C(F)(F)F)cc2)nc(N)nc1-c1ccco1,,COCCOC,,,,test
US20130274241A1,CC(C)(C)OC(=O)N1CC=C(c2ccc(-n3cc(-c4n[nH]c5ccccc45)nn3)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccc(-n3cc(-c4n[nH]c5ccccc45)nn3)cc2)CC1,[Pd],C1CCOC1,,O=C[O-].[NH4+],,test
US20160002251A1,CNC1(C(=O)OC)CCC1.Cc1ccc(S(=O)(=O)O)cc1>>CNC1(C(=O)OC)CCC1.Cc1ccc(S(=O)(=O)O)cc1,,CCOC(C)=O,,Cl,O,test
US20130225567A1,CC(C(=O)Nc1ccc(Br)c(C#C[Si](C(C)C)(C(C)C)C(C)C)n1)N(C)C(=O)OC(C)(C)C.OB(O)c1cncnc1>>CC(C(=O)Nc1ccc(-c2cncnc2)c(C#C[Si](C(C)C)(C(C)C)C(C)C)n1)N(C)C(=O)OC(C)(C)C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CO,O,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US07196104B2,Brc1cccc(Br)n1.Oc1ccc(CN2CCCC2)cc1>>Brc1cccc(Oc2ccc(CN3CCCC3)cc2)n1,,CN(C)C=O,,O,[H-].[Na+],test
US04923857,C=CCOC(=O)N1C[C@H](O)C[C@H]1C=C(C)C(C)=O.O=C(O)c1ccccc1>>C=CCOC(=O)N1C[C@@H](OC(=O)c2ccccc2)C[C@H]1C=C(C)C(C)=O,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090093474A1,CCC=O.CCOC(=O)C1CCNCC1>>CCCN1CCC(C(=O)OCC)CC1,,CCO,,,,test
US20070179130A1,O=[N+]([O-])c1ccc(Oc2ncnc3[nH]ccc23)c(F)c1>>Nc1ccc(Oc2ncnc3[nH]ccc23)c(F)c1,,CCO,,O=C[O-].[NH4+],,test
US20070155737A1,CN(C)C=O.ClCCl.NCc1ccc(F)c(F)c1.O=C(NCc1ccc(F)c(F)c1)c1cc(C(=O)O)n2ncc(C(=O)Nc3ccccc3Cl)c2n1>>COC(=O)c1ccc(CNC(=O)c2cc(C(=O)NCc3ccc(F)c(F)c3)nc3c(C(=O)Nc4ccccc4Cl)cnn23)cc1,,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US06599860B1,CC1=C(C2=NOC(CCl)C2)C(C)C(=S(=O)=O)C=C1C(=O)O.O=S(Cl)Cl>>CC1=C(C2=NOC(CCl)C2)C(C)C(=S(=O)=O)C=C1C(=O)Cl,CN(C)C=O,Cc1ccccc1,,,,test
US20110230484A1,C1COCCN1.Cc1cc(C)n(-c2nc(Cl)cc(Nc3ccc(Cl)cc3)n2)n1>>Cc1cc(C)n(-c2nc(Nc3ccc(Cl)cc3)cc(N3CCOCC3)n2)n1,,CN1CCCC1=O,,Cl,,test
US20070093521A1,CCOc1cc(C=O)ccc1Cl.O=S(=O)(c1cccc2nc(NC3CCNCC3)oc12)N1CCCC1>>CCOc1cc(CN2CCC(Nc3nc4cccc(S(=O)(=O)N5CCCC5)c4o3)CC2)ccc1Cl,,CC(=O)O,CCO,CCN(C(C)C)C(C)C,[BH3-]C#N.[Na+],test
US20120245094A1,C=CCOC[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)OC)C(C)C)C(C)C>>C=CCOC[C@H](N)C(=O)N[C@H](C(=O)N[C@H](C(=O)OC)C(C)C)C(C)C,,O=CO,,,,test
US20090042873A1,O=[N+]([O-])c1ccc2nc3n(c2c1)CCN3>>Nc1ccc2nc3n(c2c1)CCN3,[Pd],CO,,O=C[O-].[NH4+],,test
US20040116328A1,CC#CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2nc(Cl)n(C)c(=O)c21.[C-]#N>>CC#CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2nc(C#N)n(C)c(=O)c21,,CN1CCCC1=O,,O,,test
US20130005728A1,CCOC(=O)CC1CCCCN1c1cc(N(CCc2ccc(OC(F)(F)F)cc2)C(=O)OC(C)(C)C)nc(OC)n1.Cl>>CCOC(=O)CC1CCCCN1c1cc(NCCc2ccc(OC(F)(F)F)cc2)nc(OC)n1.Cl,,C1COCCO1,,,,test
US20100152190A1,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.CN(C)Cc1ccc(N)cc1>>CN(C)Cc1ccc(NC(=O)C2NC(CC(C)(C)C)C(C#N)(c3ccc(Cl)cc3F)C2c2cccc(Cl)c2F)cc1,,ClCCl,ClCCl,CCN(C(C)C)C(C)C,,test
US20110230458A1,CCCCc1nnc(O[C@@H]2CC[C@@H](NC=O)CC2)cc1-c1ccc(OC2CCCCC2)cc1>>CCCCc1nnc(O[C@@H]2CC[C@@H](NC)CC2)cc1-c1ccc(OC2CCCCC2)cc1,,C1CCOC1,,,,test
US06200978B1,O=C(O)CN1C(=O)c2ccccc2C1=O.O=C(O)[C@H]1CCCN1>>O=C1NCC(=O)N2CCC[C@H]12,,ClCCl,O,O=S(Cl)Cl,c1ccncc1,test
US05506228,CCOC(=O)CC#N.COc1ccc(NN=C(Sc2ccccc2)C(C)=O)cc1>>COc1ccc(-n2nc(Sc3ccccc3)c(C)c(C#N)c2=O)cc1,,CCO,,C,O=C[O-].[NH4+],test
US20050043388A1,NNC(=O)c1ccc(NC(=O)CCc2ccc3c(c2)OCO3)cc1.O=C1Nc2ccc(Br)cc2C1=O>>O=C(CCc1ccc2c(c1)OCO2)Nc1ccc(C(=O)NN=C2C(=O)Nc3ccc(Br)cc32)cc1,,CC(=O)O,,,,test
US20070010573A1,CC(C)N.O=S1(=O)CCCO1>>CC(C)NCCCS(=O)(=O)O,,CCOCC,ClCCl,CCCCCC,,test
US20130079313A1,CC(C)(C)OC(=O)N(c1ccc(C(=O)OCCC(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1OCC1CC1)S(C)(=O)=O>>CS(=O)(=O)Nc1ccc(C(=O)OCCC(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1OCC1CC1,,Cl,ClCCl,C1COCCO1,,test
US20090163468A1,O=c1[nH]cnn2c(C3CCC3)nc(I)c12.c1nc[nH]n1>>Nc1ncnn2c(C3CCC3)nc(I)c12,,c1ccncc1,,O=P(Cl)(Cl)Cl,,test
US20100292259A1,C1CCOC1.CC(C)(C)OC(=O)N1CCC(Oc2cc(N3CCc4cc(S(C)(=O)=O)ccc43)ncn2)CC1>>CCN(C(C)C)C(C)C,,C1CCOC1,,ClCCl,O=C(O)C(F)(F)F,test
US20130344030A1,C[C@H](N)C(=O)N1CCC[C@@H](C(=O)N[C@H](C)c2ccc3ccc(Br)cc3n2)N1.O=C(O)C(F)(F)F>>C[C@H](N)C(=O)N1CCC[C@@H](C(=O)O)N1,,ClCCl,,,,test
US05332729,CC(N)c1cccc(C#N)c1.CCOP(=O)(CC1CCCCC1)C[C@@H](O)CCl>>CCOP(=O)(CC1CCCCC1)C[C@@H](O)CNC(C)c1cccc(C#N)c1,,CCO,,CCN(C(C)C)C(C)C,,test
US20080132503A1,CC(C)(C)OC(=O)Nc1ccc(-c2ccc(CO)s2)cc1NC(=O)c1ccc(-c2cccnc2)cc1>>CC(C)(C)OC(=O)Nc1ccc(-c2ccc(C=O)s2)cc1NC(=O)c1ccc(-c2cccnc2)cc1,,ClCCl,,CC(C)O,,test
US20040224929A1,C#C/C=C(\CC)c1cccc(O)c1.O=C(OCc1ccc(CBr)cc1COC(=O)c1ccccc1)c1ccccc1>>C#C/C=C(\CC)c1cccc(OCc2ccc(COC(=O)c3ccccc3)c(COC(=O)c3ccccc3)c2)c1,,CN(C)C=O,,[H-].[Na+],,test
US20130158003A1,CN(C)S(=O)(=O)n1cc(-c2ccccc2)nc1CN.Clc1cnc2ccccc2n1>>CN(C)S(=O)(=O)n1cc(-c2ccccc2)nc1CNc1cnc2ccccc2n1,,C1CCOC1,,CCN(C(C)C)C(C)C,O=C([O-])[O-].[K+].[K+],test
US20110053923A1,CCS(=O)(=O)C1(c2cc(N3CCOC[C@H]3C)nc(Cl)n2)CCOCC1.OB(O)c1cccc2[nH]ccc12>>CCS(=O)(=O)C1(c2cc(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)n2)CCOCC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20030069236A1,BrCc1ccccc1.COC(=O)CC1CNc2cc([N+](=O)[O-])ccc2O1>>COC(=O)CC1CN(Cc2ccccc2)c2cc([N+](=O)[O-])ccc2O1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],,test
US20100331293A1,CCCC[Sn](CCCC)(CCCC)c1ccccn1.Cc1c(Cl)nc2cc(F)cc(F)c2c1Cl>>Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20040102478A1,C=CCC1(CC=C)C(=O)CN(C(=O)OC(C)(C)C)[C@@H]1C(=O)OC>>C=CCC1(CC=C)C(=O)CN[C@@H]1C(=O)O,,CO,O,Cl,[Li+].[OH-],test
US05461036,CCCCCCCCCCC(Br)C(=O)O.Oc1ccccc1>>CCCCCCCCCCC(Oc1ccccc1)C(=O)O,,CN(C)C=O,,[H-].[Na+],,test
US20150266824A1,BrP(Br)Br.O=c1c(Cl)c[nH]c2ccccc12>>Clc1cnc2ccccc2c1Br,,CN(C)C=O,,,,test
US06489321B1,CN.Cc1ccccc1C(=O)Nc1ccc(C(=O)N2C=CC(CCS(C)(=O)=O)Sc3ccccc32)cc1>>CNCCC1C=CN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc2S1,,C1CCOC1,,,,test
US20100168161A1,N#CCc1ccc(OCC(F)(F)COc2ccccc2)cc1>>NCCc1ccc(OCC(F)(F)COc2ccccc2)cc1,O=[Pt]=O,CO,,Cl,,test
US20050054683A1,CC(=O)OC(C)=O.CC1(c2ccc(N3C[C@@H](CN)OC3=O)cc2F)CN(C(=O)OCc2ccccc2)C1>>CC(=O)NC[C@H]1CN(c2ccc(C3(C)CN(C(=O)OCc4ccccc4)C3)c(F)c2)C(=O)O1,,ClCCl,,c1ccncc1,,test
US20130210818A1,C[Si](C)(C)CCOCn1c(Br)nc(Br)c1Br.OB(O)c1ccc(F)cc1>>C[Si](C)(C)CCOCn1c(-c2ccc(F)cc2)nc(Br)c1Br,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20060287341A1,CC(C)Nc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c2n[nH]c(=O)n12.CI>>CC(C)Nc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c2nn(C)c(=O)n12,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20070111982A1,NCc1cccc2cccnc12.O=C1NC(=O)C2(CCc3cc(C(=O)O)ccc3C2)N1>>O=C1NC(=O)C2(CCc3cc(C(=O)NCc4cccc5cccnc45)ccc3C2)N1,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20030176454A1,Cc1ncc(-c2cc(N)cc(Cl)c2)n1C.Clc1ncnc2c1CCc1ccccc1-2>>Cc1ncc(-c2cc(Cl)cc(Nc3ncnc4c3CCc3ccccc3-4)c2)n1C,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20160002266A1,CCOC(=O)c1ccc(C2CCN(C)CC2)cc1>>CN1CCC(c2ccc(C(=O)O)cc2)CC1,,CCO,O,Cl,[Na+].[OH-],test
US06432993B1,CN(C(=O)OC(C)(C)C)c1cc(Cl)ccc1[N+](=O)[O-].Oc1ccccc1N1CCCC1>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccccc2N2CCCC2)ccc1[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],,test
US20090270625A1,O=C([O-])N1CCC2C(c3ccc(F)cc3)Nc3ccccc3C21>>Fc1ccc([C@@H]2Nc3ccccc3[C@@H]3NCC[C@H]23)cc1,[Pd],CCO,,,,test
US20100055576A1,CC(C)(C)c1ccc(O)c(C(C)(C)C)c1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)Oc2ccc(C(C)(C)C)cc2C(C)(C)C)cc1,,CCOCC,Cc1ccccc1,O,[H-].[Na+],test
US20060258701A1,COCC(=O)Cl.NNC(N)=S>>COCc1nc(S)n[nH]1,,c1ccncc1,,,,test
US03950333,Nc1ccc(C(=O)O)nn1>>Nc1ccc(CO)nn1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20160016968A1,CC(C)(C)C(=O)Cl.NC(=NO)c1cc(OCC(F)(F)F)c(N2CC(F)(F)C2)cn1>>CC(C)(C)c1nc(-c2cc(OCC(F)(F)F)c(N3CC(F)(F)C3)cn2)no1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110301142A1,COC(=O)c1nc[nH]n1.Cc1noc(-c2ccc(CCl)cc2)c1NC(=O)OC(C)c1ccccc1Cl>>COC(=O)c1ncn(Cc2ccc(-c3onc(C)c3NC(=O)OC(C)c3ccccc3Cl)cc2)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100305096A1,CC(C)(O)C(=O)O.CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCNCC3(C)C)n(C)c2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCN(C(=O)C(C)(C)O)CC3(C)C)n(C)c2n1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140163237A1,Brc1ccc(I)cc1.CC1(C)OB(c2ccc3c(c2)c2ccccc2n3-c2ccccc2)OC1(C)C>>Brc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2ccccc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20100048568A1,Nn1ccc2cccnc21.O=C(Cl)c1cnc(-c2cccc(F)c2)nc1>>O=C(Nn1ccc2cccnc21)c1cnc(-c2cccc(F)c2)nc1,,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US04497817,CC(=O)Oc1ccc(-c2cn3c(n2)sc2ccccc23)cc1>>Oc1ccc(-c2cn3c(n2)sc2ccccc23)cc1,,CO,,CC(=O)O,[K+].[OH-],test
US04992433,O=C(OCC1CC1)c1ccc(OCc2ccccc2)cc1>>O=C(OCC1CC1)c1ccc(O)cc1,[Pd],CC(C)O,,[H][H],,test
US20110124765A1,C(=NC1CCCCC1)=NC1CCCCC1.C1CCOC1.O=C(O)/C=C/C(=O)O>>O=C1C=CC(=O)OCCCCCCCCO1,CN(C)c1ccncc1,,,,,test
US05817678,Cc1ccc(S(=O)(=O)Cl)cc1.OC[C@H]1CCCN(CC(c2ccccc2)c2ccccc2)C1>>Cc1ccc(S(=O)(=O)OC[C@H]2CCCN(CC(c3ccccc3)c3ccccc3)C2)cc1,,c1ccncc1,,,,test
US20130244929A1,COC(=O)c1ccc(CCCCCCCCc2ccccc2)cc1>>O=C(O)c1ccc(CCCCCCCCc2ccccc2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20130245021A1,CC(=O)c1ccc(B(O)O)s1.CCOC(=O)CCCNc1ccc2ncc(Br)n2n1>>CCOC(=O)CCCNc1ccc2ncc(-c3ccc(C(C)=O)s3)n2n1,,CCN(CC)CC,,,,test
US05672597,CCOC(=O)NCCS(=O)CC(=O)O.NC/C=C\COc1cccc(CN2CCCCC2)c1>>CCOC(=O)NCCS(=O)CC(=O)NC/C=C\COc1cccc(CN2CCCCC2)c1,,CN(C)C=O,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US06498172B1,CC(C)(C)OC(=O)COc1cccc(CN)c1.O=Cc1ccc(-c2ccccn2)cc1>>CC(C)(C)OC(=O)COc1cccc(CNCc2ccc(-c3ccccn3)cc2)c1,,CCN(CC)CC,,,,test
US20090023939A1,[C-]#[N+]C(=C\c1ccc(O[Si](C)(C)C(C)(C)C)cc1)/C(=C/c1ccc(O[Si](C)(C)C(C)(C)C)cc1)[N+]#[C-]>>[C-]#[N+]C(=C\c1ccc(O)cc1)/C(=C/c1ccc(O)cc1)[N+]#[C-],,C1CCOC1,,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100137275A1,CN(CCN)CCNc1cc(N2CCCC2)nc(N2CCCC2)n1.COc1ccc(C(=O)N=C=S)cc1>>COc1ccc(C(=O)NC(=S)NCCN(C)CCNc2cc(N3CCCC3)nc(N3CCCC3)n2)cc1,,ClCCl,,,,test
US05696151,CCOC(=O)CC(C)=O.COC(CCl)OC>>Cc1occc1C(=O)O,,c1ccncc1,,Cl,O,test
US20100113462A1,CCOC(=O)C1(NC(=O)c2cccc(Cl)c2OC(C)C)Cc2ccccc2C1>>CC(C)Oc1c(Cl)cccc1C(=O)NC1(C(=O)O)Cc2ccccc2C1,,CCO,,O,[K+].[OH-],test
US20040254205A1,COc1cc2nc[nH]c(=O)c2cc1OC(C)=O.Nc1ccc(Cl)cc1>>COc1cc2ncnc(Nc3ccc(Cl)cc3)c2cc1OC(C)=O,CN(C)C=O,O=S(Cl)Cl,,,,test
US05521163,CS(=O)(=O)Cl.O[C@@H](COCc1ccccc1)[C@H](CC(SCc1ccccc1)SCc1ccccc1)OCc1ccccc1>>CS(=O)(=O)O[C@@H](COCc1ccccc1)[C@H](CC(SCc1ccccc1)SCc1ccccc1)OCc1ccccc1,,c1ccncc1,,,,test
US20140206663A1,CC(C)c1cc2c(cc1OC1(C)CN(C(=O)OC(C)(C)C)C1)N1C(=NNC(=O)[C@H]1C)CO2.O=C(O)C(F)(F)F>>CC(C)c1cc2c(cc1OC1(C)CNC1)N1C(=NNC(=O)[C@H]1C)CO2.O=C(O)C(F)(F)F,,ClCCl,,,,test
US06063892,CC(C)(c1ccc([N+](=O)[O-])cc1)c1ccc([N+](=O)[O-])cc1>>CC(C)(c1ccc(N)cc1)c1ccc(N)cc1,[Pd],C1COCCO1,,,,test
US20060091322A1,C=C(C)C(=O)OCCN=C=O.Cc1cc(=O)nc(N)[nH]1>>C=C(C)C(=O)OCCNC(=O)Nc1nc(=O)cc(C)[nH]1,,c1ccncc1,,CC(C)=O,,test
US05102781,CCI.Sc1nc2cc(Cl)ccc2s1>>CCSc1nc2cc(Cl)ccc2s1,,CCO,,CCN(CC)CC,O,test
US20130059834A1,C[C@@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(C)c4cc(F)ccc34)nc12)c1ncco1>>C[C@@H](NC(=O)c1c[nH]c2ncc(-c3nn(C)c4cc(F)ccc34)nc12)c1ncco1,,ClCCl,,NCCN,O=C(O)C(F)(F)F,test
US20070197558A1,CC(Br)c1ccccc1.O=[N+]([O-])c1cc(O)ccc1Cl>>CC(Oc1ccc(Cl)c([N+](=O)[O-])c1)c1ccccc1,,CC(C)=O,,O=C([O-])[O-].[Na+].[Na+],,test
US05324859,COC(=O)c1ccc(C(=O)[O-])cc1.O=S(Cl)Cl>>COC(=O)c1ccc(C(=O)Cl)cc1,,O,,,,test
US20110160433A1,CCCCCCCCCCCCCCCCCCOCC(COCCCCCCCCCCCCCCCCCC)(COCCCCCCCCCCCCCCCCCC)COc1ccc(C=NO)c(OC)c1>>CCCCCCCCCCCCCCCCCCOCC(COCCCCCCCCCCCCCCCCCC)(COCCCCCCCCCCCCCCCCCC)COc1ccc(CN)c(OC)c1,,C1CCOC1,,Cl,,test
US04835175,CCCCOC(=O)c1cc2c(C(=O)C(NC(C)C)C(=O)OCCCC)ccc(O)c2[nH]1.Cl>>CCCCOC(=O)CC(C)NCC(O)c1ccc(O)c2[nH]c(C(=O)OCCCC)cc12.Cl,,C1CCOC1,CO,,,test
US20140051692A1,C=CC(C)O.Oc1ccncc1Br>>C=CC(C)Oc1ccncc1Br,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080021028A1,COc1ccc(N2CCN(C(=O)[C@@H](CC(C)C)[C@H]3OC(C)(C)OC3=O)CC2)cc1.NO>>COc1ccc(N2CCN(C(=O)[C@@H](CC(C)C)[C@@H](O)C(=O)NO)CC2)cc1,,CC(C)O,,,,test
US20040235932A1,CCOc1ccccc1OCCN[C@H](C)Cc1cc(C#N)c2c(c1)CCN2CCCOC(=O)c1ccccc1>>CCOc1ccccc1OCCN[C@H](C)Cc1cc(C#N)c2c(c1)CCN2CCCO,,CO,O,[K+].[OH-],,test
US20160096837A1,CN(C)/C=C1\CN(C(=O)OC(C)(C)C)CCC1=O.Nc1cc[nH]n1>>CC(C)(C)OC(=O)N1CCc2c(cnc3ccnn23)C1,,CCOC(C)=O,CN(C)C=O,,,test
US20090075971A1,CC(C)(C)OC(=O)N[C@@H](COc1cccc(-c2ccccc2)c1[N+](=O)[O-])C(=O)O>>CC(C)(C)OC(=O)N[C@@H](COc1cccc(-c2ccccc2)c1N)C(=O)O,[Pd],CO,,,,test
US20130096118A1,CCOC(C)=O.Cc1c(-c2cnc(C(N)=O)c3[nH]c4cc(O)ccc4c23)cccc1N1Cc2ccc(Cl)cc2C1=O>>Cc1c(-c2cnc(C(N)=O)c3[nH]c4cc(OCCCO)ccc4c23)cccc1N1Cc2ccc(Cl)cc2C1=O,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120022077A1,CC(=O)Nc1ccc(C=C(C#N)C#N)cc1.COC(=O)CCc1cccc(COS(C)(=O)=O)n1.NC(N)=S>>COC(=O)CCc1cccc(CSc2nc(N)c(C#N)c(-c3ccc(NC(C)=O)cc3)n2)n1,,CCN(CC)CC,CO,O=C1CCC(=O)N1Br,,test
US20120165318A1,COC(=O)c1ccc2nc(-c3ccccc3)c(Br)nc2c1.c1ccc(N2CCNCC2)nc1>>COC(=O)c1ccc2nc(-c3ccccc3)c(N3CCN(c4ccccn4)CC3)nc2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20130053381A1,CC(=O)OCC(=O)Cl.CCn1nccc1-c1cc2c(=O)n(NS(C)(=O)=O)c(=O)[nH]c2cc1C(F)F>>CCn1nccc1-c1cc2c(=O)n(N(C(=O)COC(C)=O)S(C)(=O)=O)c(=O)[nH]c2cc1C(F)F,,ClCCl,,CCN(CC)CC,,test
US20070066615A1,COC(=O)C1CC(=O)N(c2ccc(N3CCOCC3)cc2)C1>>O=C1CC(CO)CN1c1ccc(N2CCOCC2)cc1,,CO,,Cl,[BH4-].[Na+],test
US20070254867A1,C[Si](C)(C)C#N.[O-][n+]1ccc2c(Br)cccc2c1>>N#Cc1nccc2c(Br)cccc12,,CC#N,,CCN(CC)CC,,test
US20100069504A1,Br[Mg]CCc1ccccc1.C=C1C(=O)C(NC(=O)OCc2ccccc2)CCc2ccccc21>>O=C(NC1CCc2ccccc2C(CCCc2ccccc2)C1=O)OCc1ccccc1,,C1CCOC1,,[Cl-].[NH4+],,test
US20020006944A1,CCOC(=O)CBr.O=C1CCCc2ccc(O)cc21>>CCOC(=O)COc1ccc2c(c1)C(=O)CCC2,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100093757A1,CCOC=C(C#N)C#N.NNc1c(Br)cccc1Br>>N#Cc1cnn(-c2c(Br)cccc2Br)c1N,,CO,,,,test
US20020143034A1,NC(=O)c1ccc2c(Cl)ccnc2c1.OC[C@H](Cc1ccc(O)cc1)N(Cc1ccccc1)C[C@H](O)COc1ccccc1>>NC(=O)c1ccc2c(Oc3ccc(C[C@@H](CO)N(Cc4ccccc4)C[C@H](O)COc4ccccc4)cc3)ccnc2c1,,CS(C)=O,,O,CC(C)(C)[O-].[K+],test
US20050043388A1,CC(C)(C)OC(=O)NNC(=O)c1ccc(O[C@@H](Cc2ccccc2)C(=O)OCc2ccccc2)cc1.O=C1Nc2ccc(I)cc2C1=O>>O=C1Nc2ccc(I)cc2C1=NNC(=O)c1ccc(O[C@@H](Cc2ccccc2)C(=O)OCc2ccccc2)cc1,,CC(=O)O,,O=C(O)C(F)(F)F,,test
US20120225854A1,O=C1CNC(=O)[C@H](COCc2ccccc2)N1>>c1ccc(COC[C@H]2CNCCN2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150336949A1,C[C@H]1CO1.Cc1ccc(S(=O)(=O)n2cc(-c3cnn(Cc4cccc(OCc5ccccc5)c4)c3)c3cc(-c4ccc(N5CCNCC5)nc4)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3cnn(Cc4cccc(OCc5ccccc5)c4)c3)c3cc(-c4ccc(N5CCN(C[C@H](C)O)CC5)nc4)cnc32)cc1,,CCO,,CCN(C(C)C)C(C)C,Cl,test
US05668161,CS(=O)(=O)c1ccc(C(Br)C(=O)c2ccc(F)cc2)cc1.NC(=S)c1cccnc1>>CS(=O)(=O)c1ccc(-c2sc(-c3cccnc3)nc2-c2ccc(F)cc2)cc1,,CC#N,,,,test
US04317823,C1CCNC1.Cc1nn(C)c2c1N(C(=O)CCl)c1ccccc1NC2=O>>Cc1nn(C)c2c1N(C(=O)CN1CCCC1)c1ccccc1NC2=O,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20140051679A1,CN(C)CCOc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.O=C(Nc1ccc2[nH]nc(I)c2c1)C(c1ccsc1)N1CCCC1>>CN(C)CCOc1ccc(-c2n[nH]c3ccc(NC(=O)C(c4ccsc4)N4CCCC4)cc23)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20060004017A1,COc1cc2c(Oc3ccc4[nH]cc(C)c4c3)ncnc2cc1OCc1ccccc1>>COc1cc2c(Oc3ccc4[nH]cc(C)c4c3)ncnc2cc1O,[Pd],CN(C)C=O,,O=C[O-].[NH4+],,test
US20080207609A1,CC(=O)Cl.C[C@H]1CN(Cc2cc3nc(-c4cccc(O[Si](C)(C)C(C)(C)C)c4)nc(N4CCOCC4)c3s2)C[C@@H](C)N1>>CC(=O)N1[C@@H](C)CN(Cc2cc3nc(-c4cccc(O[Si](C)(C)C(C)(C)C)c4)nc(N4CCOCC4)c3s2)C[C@H]1C,,ClCCl,,CCN(CC)CC,,test
US20070167442A1,COC(CN)OC.O=C=NC1CCN(C(=O)OCc2ccccc2)CC1>>O=c1[nH]ccn1C1CCNCC1,[Pd],C1CCOC1,,,,test
US06156700,CCOP(OCC)OCC.Cn1c(C(F)(F)F)cc(=O)n(-c2ccc3snc(CBr)c3c2)c1=O>>CCOP(=O)(Cc1nsc2ccc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)cc12)OCC,,C1CCOC1,CCOCC,ClCCl,,test
US05952362,Cc1ccc([N+](=O)[O-])c(C)c1[N+](=O)[O-]>>Cc1ccc(N)c(C)c1[N+](=O)[O-],[Pd],CCN(CC)CC,CCOC(C)=O,O=CO,,test
US20080146637A1,CC(=O)c1ccccc1B(O)O.FC(F)(F)c1ccc(OCc2nc3cc(Br)ccc3[nH]2)cc1>>CC(=O)c1ccccc1-c1ccc2[nH]c(COc3ccc(C(F)(F)F)cc3)nc2c1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20140045890A1,CC(C)(C)OC(=O)NC(C)(C)c1cc([Si](C)(C)C)on1>>CC(C)(N)c1ccon1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04756742,CC(C)(C)NS(=O)(=O)c1ccsc1C1=CC(=O)CCC1>>NS(=O)(=O)c1ccsc1C1=CC(=O)CCC1,,O=C(O)C(F)(F)F,,,,test
US20100197678A1,C=CCBr.Clc1ncnc2cc[nH]c12>>C=CCn1ccc2ncnc(Cl)c21,,CN(C)C=O,,[H-].[Na+],,test
US20080312208A1,CCOC(=O)C(=CN(C)C)C(=O)C(C)C.N#CCC(N)=O>>CCOC(=O)c1cc(C#N)c(=O)[nH]c1C(C)C,,C1CCOC1,O,Cl,[H-].[Na+],test
US20020165235A1,COC(=O)c1cc(-c2ccccc2)ccc1N.O=C(Cl)Cl.OCc1cc2cc(-c3ccccc3)ccc2o1>>COC(=O)c1cc(-c2ccccc2)ccc1NC(=O)OCc1cc2cc(-c3ccccc3)ccc2o1,,Cc1ccccc1,,c1ccncc1,,test
US20090163488A1,Nc1nc2ccc(O)cn2n1.O=C(Cl)C1CC1>>O=C(Nc1nc2ccc(O)cn2n1)C1CC1,,CC(=O)N(C)C,O,Br,,test
US20120035208A1,CS(=O)(=O)c1ccc(B(O)O)cc1.Cn1ncc2c(Cl)cc(-c3cccc4[nH]ncc34)nc21>>Cn1ncc2c(-c3ccc(S(C)(=O)=O)cc3)cc(-c3cccc4[nH]ncc34)nc21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,O,O=C([O-])[O-].[Na+].[Na+],,test
US20040023964A1,CC(C)(O)c1cnn2c(Br)cnc2n1.OB(O)c1cccc(-c2ncc(F)cc2F)c1>>CC(C)(O)c1cnn2c(-c3cccc(-c4ncc(F)cc4F)c3)cnc2n1,,Cl,,,,test
US20150306122A1,CC(=O)OC(C)=O.O=c1cc(-c2ccccc2)oc2cc(O)cc(O)c12>>CC(=O)Oc1cc(OC(C)=O)c2c(=O)cc(-c3ccccc3)oc2c1,,c1ccncc1,,CCOCC,,test
US20100105679A1,CC(C)(C)[Si](C)(C)OCCCn1ncc2cc(-n3ccc(OCc4ccccc4)cc3=O)ccc21>>O=c1cc(OCc2ccccc2)ccn1-c1ccc2c(cnn2CCCO)c1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US04021451,CCOC(CN)OCC.COc1ccc(CCO)cc1OC>>COc1cc2c(cc1OC)C(CN)OCC2,,C1COCCO1,,Cl,,test
US05607960,CC(=O)CCc1ccc2[nH]cc(C[C@H]3CCCN3)c2c1>>CC(O)CCc1ccc2[nH]cc(C[C@H]3CCCN3)c2c1,,CCO,,Cl,[BH4-].[Na+],test
US05736548,CCCI.O=Cc1ccccc1O>>CCCOc1ccccc1C=O,,CN(C)C=O,,O,[H-].[Na+],test
US20080039446A1,CN1CCCC1CCN.O=C(Nc1cccc2c1C(=O)OC2=O)c1ccc(Cl)s1>>CN1CCCC1CCN1C(=O)c2cccc(NC(=O)c3ccc(Cl)s3)c2C1=O,,C1COCCO1,,,,test
US05576340,CC(=O)CBr.COC(=O)Cc1ccc(O)cc1>>COC(=O)Cc1ccc(OCC(C)=O)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110288280A1,CC(=O)Oc1ccc(-c2cnc(N)c(Cc3ccccc3)n2)cc1.O=C(Cl)Cc1ccccc1>>CC(=O)Oc1ccc(-c2cnc(NC(=O)Cc3ccccc3)c(Cc3ccccc3)n2)cc1,CN(C)c1ccncc1,c1ccncc1,,O=C([O-])O.[Na+],,test
US20130019348A1,CCOC(=O)c1ccc(OC(F)(F)C(F)(F)F)cc1.NN>>NNC(=O)c1ccc(OC(F)(F)C(F)(F)F)cc1,,CCO,,O,,test
US05741796,CC(C)(C)OC(=O)CBr.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OC(=O)COC(C)(C)C)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US06352977B1,CCOC(=O)CCN.CCOc1cc(C=O)ccc1OC>>CCOC(=O)CCNCc1ccc(OC)c(OCC)c1,,CCO,,Cl,[BH3-]C#N.[Na+],test
US20020128262A1,CC(=O)c1ccccc1N(C)C(=O)CN=[N+]=[N-].CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(=O)c1ccccc1N(C)C(=O)CNC(=O)C(C)(C)C,[Pd],,,CCOC(C)=O,,test
US04123529,O=S(Br)Br.OCc1ccc(-c2cccc(C(F)(F)F)c2)o1>>FC(F)(F)c1cccc(-c2ccc(CBr)o2)c1,,CN(C)C=O,,,,test
US04109088,CC(O)(Oc1cccc2c1CCC2)C1CNCCO1>>CC1=CCc2c(OCC3CNCCO3)cccc21,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100130468A1,C1CNC1.O=S(=O)(Cl)c1ccc(Br)s1>>O=S(=O)(c1ccc(Br)s1)N1CCC1,,ClCCl,,,,test
US20070083045A1,CC(C)(C)OC(=O)NC1(C(N)=NO)CCOCC1.COC(=O)C#CC(=O)OC>>COC(=O)C=C(ON=C(N)C1(NC(=O)OC(C)(C)C)CCOCC1)C(=O)OC,,ClC(Cl)Cl,,,,test
US04207104,CC(OC1=CC(=O)C(=O)c2ccccc21)C(=O)O.NNc1ccc(S(N)(=O)=O)cn1>>CC(Oc1cc(N=Nc2ccc(S(N)(=O)=O)cn2)c(O)c2ccccc12)C(=O)O,Cl,CC(=O)O,,,,test
US05159078,Cc1cc(C(F)(F)F)nc(Nc2ccccc2C(F)(F)F)n1.O=C=NS(=O)(=O)Cl>>Cc1cc(C(F)(F)F)nc(N(C(N)=O)c2ccccc2C(F)(F)F)n1,,CCOC(C)=O,,,,test
US20150105373A1,CO.COC(=O)Cc1nc(Cl)c(C)cc1[N+](=O)[O-]>>COC(=O)Cc1nc(OC)c(C)cc1[N+](=O)[O-],,CO,,C[O-].[Na+],,test
US20100003191A1,O=C([O-])Cc1coc2ccc(I)cc12>>O=C1COc2ccc(I)cc21,,CO,,Cl,O,test
US20030013713A1,C1CCOC1.CCCCCC.COc1cc(C=O)nnc1OC.Cc1c(Cl)cncc1Cl>>COc1cc(C(O)Cc2c(C)cncc2C)nnc1OC,,C1CCOC1,CCCCCC,CC(C)NC(C)C,[Li]CCCC,test
US20140142307A1,Br.BrCc1ccc2ccccc2c1.Clc1nc[nH]c1Cl.O=C(O)COc1ccc(CBr)cc1>>O=C(O)COc1ccc(Cn2c[n+](Cc3ccc4ccccc4c3)c(Cl)c2Cl)cc1.[Br-],,CC#N,,[K+].[OH-],,test
US20060135578A1,COC(=O)CBr.Cc1oc(-c2ccccc2)nc1COc1ccc(C(=O)c2ccccc2)c(O)c1>>COC(=O)c1oc2cc(OCc3nc(-c4ccccc4)oc3C)ccc2c1-c1ccccc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140158580A1,CO[SiH](Cl)OC.CO[SiH](N[SiH](OC)OC)OC>>CO[SiH](OC)N([SiH](OC)OC)[SiH](OC)OC,,CCCCCC,,CCN(CC)CC,,test
US20160168090A1,Cc1ccc(S(=O)(=O)OCC2CCOC2)cc1.O=C(c1c[nH]c2cccc(Cl)c12)C(F)(F)F>>O=C(c1cn(CC2CCOC2)c2cccc(Cl)c12)C(F)(F)F,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20130005574A1,C=C(OCC)c1cc(N)c(OC)c(C(=O)OC)n1>>COC(=O)c1nc(C(C)=O)cc(N)c1OC,,C1CCOC1,,Cl,,test
US05459274,CCCN(c1ccncc1)n1cc(Cl)c2ccccc21.Cl>>CCCN(c1ccncc1)n1cc(Cl)c2ccccc21.Cl,,CCOCC,,,,test
US20080159982A1,C=CCCCBr.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(S)[C@H](N)C(=O)O.CI>>C=CCCCSC(C)(C)[C@H](NC(=O)OC(C)(C)C)C(=O)OC,,C1COCCO1,O,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20120022109A1,N#Cc1cccc(CBr)c1.NCCO>>N#Cc1cccc(CNCCO)c1,,CC#N,,O=C([O-])O.[Na+],,test
US04558047,Nc1nncs1.O=CC(CO)OC(C=O)n1ccc(=O)[nH]c1=O>>O=c1ccn([C@@H]2O[C@H](CO)C(O)N(c3nncs3)C2O)c(=O)[nH]1,,CO,O,,,test
US20110201628A1,CC(N)c1ncc(F)cc1F.Cc1ccc(S(=O)(=O)n2ccc3c(Nc4cn(C)cn4)nc(Cl)nc32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(Nc4cn(C)cn4)nc(NC(C)c4ncc(F)cc4F)nc32)cc1,,CCCCO,,CCN(C(C)C)C(C)C,Cl,test
US20100305096A1,CN(CC1CN(C(=O)OC(C)(C)C)C1)C1CCOC1>>CN(CC1CNC1)C1CCOC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020103245A1,N#CC(=CNc1ccccc1)C(=O)c1cccc(OCCN2CCOCC2)c1.NNc1ccc(F)cc1>>Nc1c(C(=O)c2cccc(OCCN3CCOCC3)c2)cnn1-c1ccc(F)cc1,,CCO,O,,,test
US20110015175A1,COc1cc(N)ccc1-c1cc(C)no1.O=c1ccccn1C(=S)n1ccccc1=O>>COc1cc(N=C=S)ccc1-c1cc(C)no1,,ClCCl,,,,test
US20120077795A1,CC(C)(C)OC(=O)N1CCC2C1CCCN2c1ccc(-n2ccc(OCc3ccc(Cl)cn3)cc2=O)cn1>>O=c1cc(OCc2ccc(Cl)cn2)ccn1-c1ccc(N2CCCC3NCCC32)nc1,,CO,Cl,,,test
US20080214621A1,CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@@H](N2CCCC(Cc3cc4ccccc4cc3Cl)C2=O)CC1>>O=C1C(Cc2cc3ccccc3cc2Cl)CCCN1[C@@H]1CC[C@@H](O)CC1,,CCO,,,,test
US20100174065A1,CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CN(C(=O)OC(C)(C)C)CCO4)no2)cc1C#N.Cl>>CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CNCCO4)no2)cc1C#N.Cl,,C1COCCO1,,,,test
US20130288992A1,CC(=O)OC[C@H]1O[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>CC(=O)OC[C@H]1OC(O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,CN(C)C=O,,C,O=C[O-].[NH4+],test
US05464863,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1ccccc1C(=O)c1ccccc1>>Cc1ccc(S(=O)(=O)Nc2ccccc2C(=O)c2ccccc2)cc1,,c1ccncc1,,Cl,,test
US20090221555A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1NC2C3C=CC(C3)C12>>CC(C)(C)OC(=O)N1C(=O)C2C3C=CC(C3)C21,CN(C)c1ccncc1,,,C1CCOC1,,test
US20100261755A1,COC(=O)c1ccnc(-c2ccc(C(F)(F)F)c(C)c2)c1>>COC(=O)C1CCNC(c2ccc(C(F)(F)F)c(C)c2)C1,O=[Pt]=O,CC(=O)O,,,,test
US20080027041A1,CC(=O)Cc1ccc(O)cc1.ClCCCBr>>CC(=O)Cc1ccc(OCCCCl)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090156610A1,O=Cc1cc(Br)ccc1F.Oc1ccc(F)cc1>>O=Cc1cc(Br)ccc1Oc1ccc(F)cc1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20080132495A1,O=[N+]([O-])c1ccc(CN2CCOCC2)cc1[N+](=O)[O-]>>Cc1c(N2CCOCC2)ccc(N)c1N,,CCO,,,,test
US20050215588A1,CC(C)(C)OC(=O)N1CCC(CCO)CC1.O=C(Cl)OCCl>>CC(C)(C)OC(=O)N1CCC(CCOC(=O)OCCl)CC1,,ClCCl,,c1ccncc1,,test
US04024255,Cc1ccc2c(=O)c(C(=O)O)c[nH]c2n1.Nc1nnn[nH]1>>Cc1ccc2c(=O)c(C(=O)Nc3nnn[nH]3)c[nH]c2n1,,CN(C)C=O,,,,test
US20150376135A1,CCOC(=O)CNN.O=C(CC(=O)C(Cl)Cl)C(Cl)Cl>>CCOC(=O)Cn1nc(C(Cl)Cl)cc1C(Cl)Cl,,CCO,,Cl,,test
US20090215803A1,Cc1cc(C(=O)/C=C/c2cccc(C(=O)O)c2)ccc1O.NC(N)=O>>Cc1cc(-c2cc(-c3cccc(C(=O)O)c3)[nH]c(=O)n2)ccc1O,,C1COCCO1,Cl,,,test
US20040002492A1,COc1ccccc1Sc1ccccc1CC(=O)O>>COc1cccc2c1Sc1ccccc1CC2=O,,CS(=O)(=O)O,,,,test
US20160152621A1,COc1cc([N+](=O)[O-])ccc1-c1cnco1>>O=[N+]([O-])c1ccc(-c2cnco2)c(O)c1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20060217551A1,CC(C)(C)OC(=O)N1C[C@H](O)[C@@H](CCc2ccccc2)C1.Cl>>Cl.O[C@H]1CNC[C@@H]1CCc1ccccc1,,CO,,,,test
US20120114696A1,C#Cc1ccccc1.CCOC(=O)Cc1cc(C(=O)c2ccc(I)c([N+](=O)[O-])c2)sc1Br>>CCOC(=O)Cc1cc(C(=O)c2ccc(C#Cc3ccccc3)c([N+](=O)[O-])c2)sc1Br,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,O,CCN(CC)CC,O=C([O-])[O-].[K+].[K+],test
US20130203731A1,C1COCCN1.CC(C)(O)c1ccc(C(=O)Nc2cc(Cl)n3nc(C4CC4)cc3n2)cc1>>CCc1cc2nc(NC(=O)c3ccc(C(C)(C)O)cc3)cc(N3CCOCC3)n2n1,,CN1CCCC1=O,,,,test
US20090176841A1,Cc1c(N)cccc1[N+](=O)[O-].ClC(Cl)(Cl)Cl.O=C(O)C(F)(F)F>>Cc1c(N=C(Cl)C(F)(F)F)cccc1[N+](=O)[O-],,CCCCCC,,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060276446A1,CCOC(=O)N1CCc2c(cnc3nc(C(OC(C)=O)C4(Br)C(=O)N5C(C(=O)OCc6ccc([N+](=O)[O-])cc6)=CS[C@@H]54)nn23)C1>>CCOC(=O)N1CCc2c(cnc3nc(C=C4C(=O)N5C(C(=O)O)=CSC45)nn23)C1,[Pd],C1CCOC1,,CC#N,,test
US20100286152A1,CN1CCNCC1.O=CC(=O)O.OB(O)c1cccc(OC(F)(F)F)c1>>CN1CCN(C(C(=O)O)c2cccc(OC(F)(F)F)c2)CC1,,CC#N,,O,,test
US20090221555A1,CNC(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.COCCN1CCc2cc(N)c(OC)cc2CC1>>CNC(=O)c1ccccc1Nc1nc(Nc2cc3c(cc2OC)CCN(CCOC)CC3)ncc1Cl,,CC(C)O,,C1COCCO1,Cl,test
US20140018533A1,CCOC(=O)C1=C(NCCOC)OCC1=O.O=Cc1c[nH]c2ncccc12>>CCOC(=O)C1=C(NCCOC)OC(=Cc2c[nH]c3ncccc23)C1=O,C1CCNCC1,CCO,,,,test
US06265575B1,COC(=O)c1ccc(O[C@@H]2CCCC[C@H]2N2CCCCC2)cc1>>O=C(O)c1ccc(O[C@@H]2CCCC[C@H]2N2CCCCC2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20120277243A1,CC(C)=CC(=O)n1nnc2ccccc21.NNc1ccc(Br)cn1>>CC1(C)CC(=O)N(c2ccc(Br)cn2)N1,,C1CCOC1,,CCN(CC)CC,,test
US20150158847A1,CCOC(=O)Nc1nc2cc(-c3cnn(C)c3)cnc2n1Cc1ccc(OC(c2ccc(OC)nc2)C2CC2)c(OC)c1>>COc1ccc(C(Oc2ccc(Cn3c(N)nc4cc(-c5cnn(C)c5)cnc43)cc2OC)C2CC2)cn1,,CCCCO,O,[K+].[OH-],,test
US20040023989A1,CC(C)(C)c1[nH]nc(C(=O)O)c1[N+](=O)[O-].CN(C)C=O>>CC(C)(C)c1[nH]nc(C(N)=O)c1[N+](=O)[O-],,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20080146614A1,Cc1c(C(=O)NC2CCC(F)(F)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(O[Si](C)(C)C(C)(C)C)cc1.O=C1CCC(=O)N1Br>>CC(C)(C)[Si](C)(C)Oc1ccc(-c2c(CBr)c(C(=O)NC3CCC(F)(F)CC3)nn2-c2ccc(Cl)cc2Cl)cc1,,ClCCCl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20070066607A1,NC1(C(=O)O)Cc2ccccc2C1>>NC1(CO)Cc2ccccc2C1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060004084A1,O=C(Cl)C(=O)Cl.O=C1Nc2ccccc2C1=C1OCc2cc(C(=O)O)ccc21>>O=C1Nc2ccccc2C1=C1OCc2cc(C(=O)Cl)ccc21,CN(C)C=O,CCOCC,,ClCCl,,test
US20140206681A1,Nc1cc(C2CC2)ccn1.O=C(O)c1ccc(Br)c(OC2CC2)c1>>O=C(Nc1cc(C2CC2)ccn1)c1ccc(Br)c(OC2CC2)c1,CN(C)c1ccncc1,ClCCl,,CN(C)C=O,O=S(Cl)Cl,test
US06133457,Cc1ccc(S(=O)(=O)OC[C@H](O[Si](C)(C)C(C)(C)C)[C@H](C)CCc2ccccc2)cc1.O=C1CCC(=O)N1Br>>Cc1ccc(S(=O)(=O)OC[C@H](O[Si](C)(C)C(C)(C)C)[C@H](C)CC(Br)c2ccccc2)cc1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20120225844A1,COC(CNC(=O)c1cc(COc2ccccc2)n[nH]1)OC>>O=C1NCC(O)n2nc(COc3ccccc3)cc21,,CC(C)=O,O,Cl,,test
US20090028868A1,CC(C)=O.CN(C(=O)OC(C)(C)C)c1cc(Oc2cccc(N)c2)ccc1[N+](=O)[O-]>>CC(C)Nc1cccc(Oc2ccc([N+](=O)[O-])c(N(C)C(=O)OC(C)(C)C)c2)c1,,C1CCOC1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20150368265A1,CNC(=O)c1c(-c2ccnc(OC)c2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CO4)cc12>>CNC(=O)c1c(-c2cc[nH]c(=O)c2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CO4)cc12,,CC(=O)O,,Br,,test
US07074801B1,CSC.Fc1ccc(Br)cc1N=C(c1ccccc1)c1ccccc1>>CSc1ccc(F)c(N=C(c2ccccc2)c2ccccc2)c1,,C1CCOC1,O,[Li]CCCC,[Cl-].[NH4+],test
US20110251176A1,CC(C)(C)OC(=O)Nc1sc(-c2c(F)cccc2F)nc1C(=O)Nc1cnn(CC(F)F)c1>>Nc1sc(-c2c(F)cccc2F)nc1C(=O)Nc1cnn(CC(F)F)c1,,C1COCCO1,,Cl,,test
US05798311,CC(C)(C)OC(=O)NC1(C)CN(C(=O)Nc2ccc(C(F)(F)F)cc2)N=C1c1ccc(Cl)cc1>>CC1(N)CN(C(=O)Nc2ccc(C(F)(F)F)cc2)N=C1c1ccc(Cl)cc1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20150158865A1,CC(C)(C)OC(=O)N1CCC[C@H](O)C1.Oc1nccc2ccccc12>>CC(C)(C)OC(=O)N1CCC[C@@H](Oc2nccc3ccccc23)C1,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05364871,CC(=O)NCc1cccc(C(=O)CBr)n1.NC(=S)N=C(N)N>>CC(=O)NCc1cccc(-c2csc(N=C(N)N)n2)n1,,CCO,,,,test
US20130210844A1,CC(C)(C)OC(=O)NCc1ccc(Cl)c(C(=O)O)c1F.Nc1cccc2c(Nc3cccc(C(F)(F)F)c3)ncnc12>>CC(C)(C)OC(=O)NCc1ccc(Cl)c(C(=O)Nc2cccc3c(Nc4cccc(C(F)(F)F)c4)ncnc23)c1F,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20060025459A1,CC(C)(C)O.COC(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1>>COC(=O)c1cc(C(=O)OC(C)(C)C)cc([N+](=O)[O-])c1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20040253177A1,CCCCCCCCC(O)CCCCCOCc1ccccc1>>CCCCCCCCC(O)CCCCCO,[Pd],CO,,,,test
US20150157622A1,CCOC(=O)Oc1c(OC)cc(C(=O)O[C@@H]2C[C@@H]3CN4CCc5c([nH]c6cc(OC(=O)OC(C)(C)C)ccc56)[C@H]4C[C@@H]3[C@H](C(=O)OC)[C@H]2OC)cc1OC>>CCOC(=O)Oc1c(OC)cc(C(=O)O[C@@H]2C[C@@H]3CN4CCc5c([nH]c6cc(O)ccc56)[C@H]4C[C@@H]3[C@H](C(=O)OC)[C@H]2OC)cc1OC,,CC#N,,Cl,,test
US05053422,CCOC(=O)CCC(C)=O.NCC(N)=O>>CC12CCC(=O)N1CC(=O)N2,,O,,Cl,[Na+].[OH-],test
US20120094999A1,CC(C)(C)OC(=O)Nc1cccc(O)c1.C[Si](C)(C)CCOCn1cc(I)c2c(Cl)ncnc21>>CC(C)(C)OC(=O)Nc1cccc(Oc2ncnc3c2c(I)cn3COCC[Si](C)(C)C)c1,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20110294776A1,CN(C)S(=O)(=O)Cl.Nc1ncnn2c(C3CCNCC3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12>>CN(C)S(=O)(=O)N1CCC(c2cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c3c(N)ncnn23)CC1,,Cc1ccccc1,,CCN(CC)CC,,test
US20090137564A1,CON(C)C(=O)c1ccccc1.FC(F)(F)C1CO1>>O=C(c1ccccc1)C1(C(F)(F)F)CO1,,C1CCOC1,CCCCCC,CCOCC,[Li]CCCC,test
US04420225,FC(F)(F)c1ccccc1CCl.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>FC(F)(F)c1ccccc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Cl-],,Cc1ccccc1C,,,,test
US20150376182A1,BrP(Br)Br.Oc1ccnc2ccccc12>>Brc1ccnc2ccccc12,,CN(C)C=O,,,,test
US20070208005A1,CC(C)(C)OC(=O)N1CCc2ccc(Cc3cnc(C(=O)O)cn3)cc2CC1.CC(N)=NO>>Cc1noc(-c2cnc(Cc3ccc4c(c3)CCN(C(=O)OC(C)(C)C)CC4)cn2)n1,,ClCCl,,,,test
US20130172384A1,COc1ccc(B(O)O)c(Cl)c1.Cn1nc(-c2ccc(Br)cc2)n(C[C@@H]2CCN(C(=O)C3CC3)C2)c1=O>>COc1ccc(-c2ccc(-c3nn(C)c(=O)n3C[C@@H]3CCN(C(=O)C4CC4)C3)cc2)c(Cl)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20120302570A1,CC(C(=O)NN)c1cc2cccnc2cc1F.Clc1ccc(Cl)nn1>>CC(c1cc2cccnc2cc1F)c1nnc2ccc(Cl)nn12,,CCCCO,,,,test
US20090105253A1,CCNC(=O)c1ccc(N=[N+]=[N-])cc1.CCOC(=O)CC(=O)C=C(C)C>>CCNC(=O)c1ccc(-n2nnc(C(=O)O)c2C=C(C)C)cc1,,CCO,,C,C[O-].[Na+],test
US04163846,CI.N#Cc1c(N)n[nH]c1N>>Cn1nc(N)c(C#N)c1N,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140005172A1,CCOC(=O)C(C(C)=O)C(C)C.N=C(N)N>>Cc1[nH]c(N)nc(=O)c1C(C)C,,CO,,Cl,C[O-].[Na+],test
US04608379,C1CCNCC1.CCCCCCBr.CCOCC.CN(C)c1ccc(C=O)cc1.Cc1ccncc1>>CCCCCCCCCCCC[n+]1ccccc1C=Cc1ccc(N(C)C)cc1.[Br-],,CO,,,,test
US20160095858A1,CC(C)(O)COc1cc(F)cc(Br)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(C)(O)COc1cc(F)cc(B2OC(C)(C)C(C)(C)O2)c1,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20160122318A1,CCS(=O)(=O)c1ccc([C@H](CCO)NC(=O)OC(C)(C)C)cc1>>CCS(=O)(=O)c1ccc([C@@H](N)CCO)cc1,,CC#N,,Cl,,test
US05506267,CCCCCCCCCCCCCCCC(=O)Cl.CCN(CC)CC.CN(C)c1ccccn1.COc1ccc(COC(=O)CCSCC(O)CO)cc1.ClCCl.O=C(O)CC(O)(CC(=O)O)C(=O)O>>CCCCCCCCCCCCCCCC(=O)OCC(CSCCC(=O)OCc1ccc(OC)cc1)OC(=O)CCCCCCCCCCCCCCC,,CCN(CC)CC,ClCCl,,,test
US20040044000A1,C=CCI.CC(C)(C)OC(=O)c1ccc(CNC(=O)c2cc(Br)ccc2I)cc1>>C=CCN(Cc1ccc(C(=O)OC(C)(C)C)cc1)C(=O)c1cc(Br)ccc1I,,CCOC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050086747A1,CNCC(O)CO.COc1ccc([N+](=O)[O-])c(Cl)n1>>COc1ccc([N+](=O)[O-])c(CNCC(O)CO)n1,,CCO,,,,test
US20030195210A1,CCCc1nc(C)n2c(=O)[nH]c(-c3ccccc3OCC)nc12.O=S(=O)(O)Cl>>CCCc1nc(C)n2c(=O)[nH]c(-c3cc(S(=O)(=O)Cl)ccc3OCC)nc12,,ClCCl,,,,test
US20030055057A1,COc1ccc2nc(-c3ccccc3)n(Cc3ccccc3)c2c1>>Oc1ccc2nc(-c3ccccc3)n(Cc3ccccc3)c2c1,,CCOC(C)=O,,Br,O=C([O-])O.[Na+],test
US20120184542A1,COC(=O)CC(=O)Cl.Nc1cc(C(=O)NCc2ccccc2)ccc1Cl>>COC(=O)CC(=O)Nc1cc(C(=O)NCc2ccccc2)ccc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160166560A1,COc1cc(CN2CCC(N(C)C(=O)n3cnc(-c4ccc(OS(N)(=O)=O)cc4)c3)CC2)ccc1F.O=C(O)C(=O)O>>COc1cc(CN2CCC(N(C)C(=O)n3cnc(-c4ccc(OS(N)(=O)=O)cc4)c3)CC2)ccc1F.O=C(O)C(=O)O,,CO,,O,O,test
US20130217666A1,C#C[C@@](C)(O)c1cc(C)on1.NC(=O)c1cn2c(n1)CCOc1ccc(Cl)nc1-2>>Cc1cc([C@](C)(O)C#Cc2ccc3c(n2)-n2cc(C(N)=O)nc2CCO3)no1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US05703250,C=C(C)CC1(O)CC2CCC1(C)C2(C)C.O=C(OO)c1cccc(Cl)c1>>CC1(CC2(O)CC3CCC2(C)C3(C)C)CO1,,ClCCl,,O=C([O-])O.[Na+],,test
US20100227858A1,CS(=O)(=O)Cl.C[C@H]1COCCN1c1cc(CO)nc(-c2ccc3[nH]ccc3c2)n1>>C[C@H]1COCCN1c1cc(COS(C)(=O)=O)nc(-c2ccc3[nH]ccc3c2)n1,,ClCCl,,CCN(CC)CC,,test
US20120316161A1,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1Cl.OB(O)c1ccc(F)cc1F>>CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc(F)cc1F,,COCCOC,O,CCN(C(C)C)C(C)C,,test
US04659390,OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O.[Ca]>>OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O.[Ca],,O,,,,test
US20090137572A1,Cc1nc(N=CN(C)C)sc1C(=O)C=CN(C)C.N=C(N)Nc1ccc(S(=O)(=O)NCCO)cc1>>Cc1nc(N)sc1-c1ccnc(Nc2ccc(S(=O)(=O)NCCO)cc2)n1,,CC#N,,,,test
US20110294776A1,CC(=O)CCl.Nc1ncnn2c(CCCN3CCNCC3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12>>CC(=O)CN1CCN(CCCc2cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c3c(N)ncnn23)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080009477A1,NCCc1cc(F)cc(F)c1.O=C=Nc1cccc(OC(F)F)c1>>O=C(NCCc1cc(F)cc(F)c1)Nc1cccc(OC(F)F)c1,,CCCCCC,ClCCl,NN,,test
US20130203727A1,CCOC(=O)C(OCc1ccc(OC)cc1)c1c(C)cc2c(OC)cccc2c1-c1ccc(Cl)cc1>>CCOC(=O)C(O)c1c(C)cc2c(OC)cccc2c1-c1ccc(Cl)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05508437,CC(C)(C)OC(=O)C=Cc1ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)OC(c2ccccc2)c2ccccc2)cc1>>CC(C)(C)OC(=O)CCc1ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)O)cc1,[Pd],CC(C)(C)O,,[H][H],,test
US20110315965A1,Brc1ccc(Br)c2ccccc12.OB(O)c1cc2ccccc2c2ccccc12>>Brc1cc(-c2cc3ccccc3c3ccccc23)cc2ccccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20140094473A1,CCOC(=O)CC(N)C(C)(C)CC.N#Cc1cc(F)c(Cl)nc1Cl>>CCOC(=O)CC(Nc1nc(Cl)c(C#N)cc1F)C(C)(C)CC,,CC#N,,CCN(CC)CC,,test
US04515793,O=C(CCCl)c1ccco1.OCc1ccc(N2CCNCC2)cc1Cl>>CC(C(=O)c1ccco1)N1CCN(c2ccc(CO)c(Cl)c2)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20120245144A1,CON(C)C(=O)C1CCN(C(=O)OC(C)(C)C)C1.C[Mg]Cl>>CC(=O)C1CCN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,[Cl-].[NH4+],,test
US20100256097A1,CN=C=O.OCc1nccc(Cl)n1>>CNC(=O)OCc1nccc(Cl)n1,Cl[Cu],CN(C)C=O,,O,,test
US20060235030A1,CN.Cc1c(F)cc(C(=O)O)cc1-c1nc(NCCN(C)C)nc2c1CNC(=O)N2c1c(F)cccc1F>>CNC(=O)c1cc(F)c(C)c(-c2nc(NCCN(C)C)nc3c2CNC(=O)N3c2c(F)cccc2F)c1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130203076A1,CC(C)(C)OC(=O)CBr.CC=C1N(C)C(C)CC1(c1ccccc1)c1cccc(O)c1>>CC=C1N(C)C(C)CC1(c1ccccc1)c1cccc(OCC(=O)OC(C)(C)C)c1,,CCOC(C)=O,CS(C)=O,[K+].[OH-],,test
US20150133498A1,COc1cc2oc(C(=O)O)c(C)c2cc1OC.Nc1ccccc1>>COc1cc2oc(C(=O)Nc3ccccc3)c(C)c2cc1OC,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04599333,CC(C)(N)CS.Clc1ccc(Cl)nn1>>CC(C)(N)CSc1ccc(Cl)nn1,,c1ccccc1,,[H-].[Na+],,test
US20160095858A1,CC(C)(C)c1ccc(C(=O)NS(=O)(=O)c2cccc([N+](=O)[O-])c2)c(Cl)n1>>CC(C)(C)c1ccc(C(=O)NS(=O)(=O)c2cccc(N)c2)c(Cl)n1,[Zn],CC(=O)O,,,,test
US04092311,CCOC(=O)NN.Cc1cc(Cl)nnc1-c1ccc(C#N)cc1>>CCOC(=O)NNc1cc(C)c(-c2ccc(C#N)cc2)nn1,,CCCCO,,,,test
US04485113,CN(SC(C)(C)CCl)C(=O)Cl.ON=C1CSCCS1>>CN(SC(C)(C)CCl)C(=O)ON=C1CSCCS1,,C1COCCO1,O,CCN(CC)CC,,test
US20150031708A1,CNC.COc1ncc(-c2nc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)ccc2C)cc1C(=O)O>>COc1ncc(-c2nc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)ccc2C)cc1C(=O)N(C)C,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100144731A1,Clc1nc(Cl)c2c(n1)CCC2.Oc1ccccc1>>Clc1nc2c(c(Oc3ccccc3)n1)CCC2,[Cu],CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100323994A1,Nc1cccc(Br)n1.O=C(Nc1ccncc1F)c1cnc2c(Br)cc(Cl)nn12>>O=C(Nc1ccncc1F)c1cnc2c(Nc3cccc(Br)n3)cc(Cl)nn12,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US04299830,CCCC(=O)OC(=O)CCC.Nc1ccc2c(c1)N1CCN(C(=O)C3CC3)C(C2)C1>>CCCC(=O)Nc1ccc2c(c1)N1CCN(C(=O)C3CC3)C(C2)C1,,c1ccncc1,,,,test
US20050090533A1,Cc1cc(F)ccc1-c1cc(N2CCN(Cc3ccccc3)C[C@H]2C)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1cc(F)ccc1-c1cc(N2CCNC[C@H]2C)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,CC(=O)O,,,,test
US20080318974A1,CC(C)(C)OC(=O)N1CCCC(COc2ccc(C(F)(F)F)cc2N)C1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N1CCCC(COc2ccc(C(F)(F)F)cc2NC(=O)Oc2ccc([N+](=O)[O-])cc2)C1,,ClCCl,,c1ccncc1,,test
US20090149475A1,CC(C)(C)OC(=O)n1cc(C=O)c2cc(F)ccc21.NC(=O)c1[nH]cnc1N>>CC(C)(C)OC(=O)n1cc(CNc2nc[nH]c2C(N)=O)c2cc(F)ccc21,,CO,,Cl,[BH3-]C#N.[Na+],test
US20140080800A1,CC(=O)N1CC(COC(=O)Nc2cc(-c3cccs3)ccc2[N+](=O)[O-])C1>>CC(=O)N1CC(COC(=O)Nc2cc(-c3cccs3)ccc2N)C1,[Zn],C1CCOC1,CO,O=C[O-].[NH4+],,test
US20050137224A1,CC(C)(C)OC(=O)N1[C@H]2CC[C@H]([C@H](O)[C@@H]2O)[C@H]1C(=O)N1CCC[C@H]1C#N.Cl>>Cl.N#C[C@@H]1CCCN1C(=O)[C@H]1N[C@H]2CC[C@@H]1[C@H](O)[C@@H]2O,,C1COCCO1,ClC(Cl)Cl,,,test
US20080214641A1,CC(C)C(=O)Cl.NC(=O)C(Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1>>CC(C)C(=O)NC(=O)C(Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20040138462A1,COc1ccc(S(=O)(=O)c2ccc(CCN(Cc3ccccc3)C[C@H](O)COc3cccc4[nH]ccc34)cc2)cc1.Clc1ccccc1>>COc1ccc(S(=O)(=O)c2ccc(CCNC[C@H](O)COc3cccc4[nH]ccc34)cc2)cc1.Cl,[Pd],CO,,[H][H],,test
US20160009683A1,CCOC(=O)C(F)(F)Br.CN(C(=O)OCc1ccccc1)c1ccccc1I>>CCOC(=O)C(F)(F)c1ccccc1N(C)C(=O)OCc1ccccc1,[Cu],CS(C)=O,,,,test
US20020128315A1,O=C(CBr)OCc1ccccc1.O=C(OCc1ccccc1)c1ccc(CNCc2ccccc2)cc1>>CCOC(=O)N(Cc1ccccc1)Cc1ccc(C(=O)OCc2ccccc2)cc1,,CN(C)C=O,,,,test
US20070259936A1,C#CC(=O)O.Cl.Nc1ccc(Br)cc1N>>ClC=Cc1nc2ccccc2[nH]1,,OCCO,,Cl,,test
US20090264428A1,CON(C)C(=O)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1.Clc1ccccc1-c1ccccc1Br>>CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)c2ccccc2-c2ccccc2Cl)C1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20080139390A1,CCOC(=O)C(C)=C(N)C(F)(F)F.CNN>>Cc1c(O)nn(C)c1C(F)(F)F,,O=C([O-])O,[Na+],,,test
US20100093757A1,CC(C)(C)[Si](C)(C)Cl.CCOC[C@H](O)C(=O)OC>>CCOC[C@H](O[Si](C)(C)C(C)(C)C)C(=O)OC,,CN(C)C=O,,c1c[nH]cn1,,test
US20120165331A1,CCCC[Sn](CCCC)(CCCC)c1ccco1.Cc1cc(C)nc(N2CCC3(CC2)OCCN(Cc2ccccc2Br)C3=O)n1>>Cc1cc(C)nc(N2CCC3(CC2)OCCN(Cc2ccccc2-c2ccco2)C3=O)n1,,C1COCCO1,,,,test
US20160031934A1,COc1ccc(C[C@H](NC(=O)[C@@H](C)NC(=O)CC(C)(C)O)C(=O)N[C@@H](CC2CCCC2)C(=O)[C@@]2(C)CO2)cc1OCc1ccccc1>>COc1ccc(C[C@H](NC(=O)[C@@H](C)NC(=O)CC(C)(C)O)C(=O)N[C@@H](CC2CCCC2)C(=O)[C@@]2(C)CO2)cc1O,[Pd],CO,,,,test
US20010019823A1,CC(=O)O[C@@H]1O[C@H](COC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1.Oc1cccc2ccccc12>>OC[C@H]1O[C@@H](Oc2cccc3ccccc23)[C@H](O)[C@@H]1O.Oc1cccc2ccccc12,,ClCCl,,FB(F)F,,test
US20080045514A1,CC(C)=O.COc1ccccc1-c1nnc2n1N=C(c1ccc(N)cc1)CS2>>COc1ccccc1-c1nnc2n1N=C(c1ccc(NC(C)C)cc1)CS2,CC(=O)O,CCOC(C)=O,CO,[BH3-]C#N.[Na+],,test
US20070060754A1,CCc1nc2c(N)nc3cc(O)ccc3c2n1CC1CCOCC1.O=C(CBr)N1CCOCC1>>CCc1nc2c(N)nc3cc(OCC(=O)N4CCOCC4)ccc3c2n1CC1CCOCC1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20050119256A1,COC(=O)[C@H](Cc1cc(I)c(O)c(I)c1)NC(=O)C(F)(F)F.OCc1ccc(Oc2ccc(O)cc2)cc1>>COC(=O)[C@H](Cc1cc(I)c(OCc2ccc(Oc3ccc(O)cc3)cc2)c(I)c1)NC(=O)C(F)(F)F,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06218431B1,CCCC=Cc1c(C(C)C)nc(C(C)C)c(CO)c1-c1ccc(Cl)cc1Cl>>CCCCCc1c(C(C)C)nc(C(C)C)c(CO)c1-c1ccc(Cl)cc1Cl,,CCCCCC,CCOC(C)=O,,,test
US05143935,CCOC(=O)[C@@H]1CC(OS(C)(=O)=O)CN1CC.[N-]=[N+]=[N-]>>CCOC(=O)[C@@H]1CC(N=[N+]=[N-])CN1CC,,O,,CN(C)C=O,,test
US20130018049A1,CCOC(=O)c1c(C)nc2c(c1O)c1c(n2C2CC2)CCCC1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1c(C)nc2c(c3c(n2C2CC2)CCCC3)c1OS(=O)(=O)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20130296555A1,CC(C)(C)OC(=O)N1C[C@H](N(OCc2ccccc2)C(=O)Cl)CC[C@H]1c1ncns1.Cl>>Cl.O=C(Cl)N(OCc1ccccc1)[C@@H]1CC[C@@H](c2ncns2)NC1,,C1COCCO1,Cl,,,test
US05556981,COc1cccc(-c2ccc3c(ccn3[Si](C(C)C)(C(C)C)C(C)C)c2)c1C1=NC(C)(C)CO1>>COc1cccc(-c2ccc3[nH]ccc3c2)c1C1=NC(C)(C)CO1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05294612,CCc1nn(C2CCCC2)c(N)c1C#N.O=S(=O)(O)O>>CCc1nn(C2CCCC2)c(N)c1C(N)=O,,[NH4+],[OH-],,,test
US20050059650A1,Brc1ccccn1.CCN(CC1CCNCC1)c1ncnc2c1cnn2-c1ccc(S(C)(=O)=O)cc1F>>CCN(CC1CCN(c2ccccn2)CC1)c1ncnc2c1cnn2-c1ccc(S(C)(=O)=O)cc1F,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20150080549A1,CN(C)C(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC(C)(C)C>>CN(C)C(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20130158003A1,CCOC(=O)/C=C/c1c(C)ncc(C)c1N>>Cc1ncc(C)c2[nH]c(=O)ccc12,,CCO,,C,C[O-].[Na+],test
US04137313,COC(=O)C1=C(O)c2c(c3ccccc3n2C)S(=O)(=O)N1C.Nc1ccccc1>>CN1C(C(=O)Nc2ccccc2)=C(O)c2c(c3ccccc3n2C)S1(=O)=O,,Cc1ccccc1,,,,test
US20080146542A1,CCOC(=O)c1cc2c(NC(=O)c3ccc(OC)cc3)nn(C(C)OCC)c2s1>>CCOC(C)n1nc(NC(=O)c2ccc(OC)cc2)c2cc(C(=O)O)sc21,,C1CCOC1,,[Na+].[OH-],,test
US20060211603A1,CC(=O)c1ccccc1.COC(=O)C(=O)OC>>COC(=O)C(=O)CC(=O)c1ccccc1,,CO,,C[O-].[Na+],,test
US20130066055A1,CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C(=O)OCc1ccccc1)[C@@H](C)c1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)CCCC(=O)O)C(C)C.O=C1CCC(=O)N1O>>CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C(=O)OCc1ccccc1)[C@@H](C)c1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)CCCC(=O)ON1C(=O)CCC1=O)C(C)C,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20080207608A1,Cc1cc(N2CCOCC2)c2ccccc2n1.O=[Se]=O>>O=Cc1cc(N2CCOCC2)c2ccccc2n1,,C1COCCO1,,,,test
US20120214785A1,CC(C)Oc1ccc(C=O)nc1.COP(=O)(OC)C(=[N+]=[N-])C(C)=O>>C#Cc1ccc(OC(C)C)cn1,,CCOC(C)=O,CO,O=C([O-])[O-].[K+].[K+],,test
US20080045561A1,C1COCCN1.COc1cc2c(nc1OC)c(-c1cc3cccnc3n1S(=O)(=O)c1ccc(C)cc1)cn2CCI>>COc1cc2c(nc1OC)c(-c1cc3cccnc3n1S(=O)(=O)c1ccc(C)cc1)cn2CCN1CCOCC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150266867A1,CC(C)(C)OC(=O)Nc1nc(/C(=N/OC(C)(C)C(=O)OC(C)(C)C)C(=O)O)cs1.Cc1nnnn1C[C@H]1NC(=O)[C@H]1N>>Cc1nnnn1C[C@H]1NC(=O)[C@H]1NC(=O)/C(=N\OC(C)(C)C(=O)OC(C)(C)C)c1csc(NC(=O)OC(C)(C)C)n1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05543419,COC(=O)C(CCSC)c1ccccc1.O[C@H]1CN2CCC1CC2>>CSCCC(C(=O)O[C@H]1CN2CCC1CC2)c1ccccc1,,Cc1ccccc1,,[H-].[Na+],,test
US20080200471A1,Brc1cncc(Br)c1.CO[C@H]1CCNC1>>CO[C@H]1CCN(c2cncc(Br)c2)C1,[Cu]I,CS(C)=O,,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US20130053366A1,CN1CCc2[nH]c3ccc(OC(F)(F)F)cc3c2C1.c1cc(C2CO2)ccn1>>CN1CCc2c(c3cc(OC(F)(F)F)ccc3n2CC(O)c2ccncc2)C1,,CN(C)C=O,,[H-].[Na+],,test
US20130005705A1,Cc1ccnc(-c2ccccc2)[n+]1[O-].O=P(Cl)(Cl)Cl>>ClCc1ccnc(-c2ccccc2)n1,,C1COCCO1,,,,test
US05233035,NOC(C(=O)OC(c1ccccc1)c1ccccc1)c1ccsc1.O=C(O)C(=O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>O=C(O)/C(=N\OC(C(=O)OC(c1ccccc1)c1ccccc1)c1ccsc1)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,CO,,,,test
US20040224996A1,CCOC(=O)CCCBr.Cc1c(Cl)cccc1S(=O)(=O)Nc1nc(CCN)cs1>>Cc1c(Cl)cccc1S(=O)(=O)Nc1nc(CCN2CCCC2=O)cs1,,CCO,CS(C)=O,CCN(C(C)C)C(C)C,[I-].[K+],test
US20150166483A1,C#Cc1cc(Nc2cc(Oc3ccc(N)c4ccccc34)ccn2)cc(C(=O)NCCOCCOCCOC)c1.COc1c(NC(=O)Oc2ccccc2)cc(C(C)(C)C)cc1NS(C)(=O)=O>>C#Cc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)cc(NS(C)(=O)=O)c4OC)c4ccccc34)ccn2)cc(C(=O)NCCOCCOCCOC)c1,,CC(=O)OC(C)C,,CCN(CC)CC,,test
US20110172297A1,CC(C)S(=O)(=O)Cl.N[C@@H]1COCC[C@@H]1c1ccc(I)cc1>>CC(C)S(=O)(=O)N[C@@H]1COCC[C@@H]1c1ccc(I)cc1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20070054912A1,CC(=O)O.CC(=O)OC(C)=O.O=c1[nH]c2cc(Cl)c(S(=O)(=O)Cl)cc2o1>>CC(=O)Sc1cc2oc(=O)n(C(C)=O)c2cc1Cl,[Zn],CC(=O)OC(C)=O,,CC(=O)[O-].[Na+],,test
US04621097,CCOC(=O)CN1C[C@@H]2CCCCC[C@@H]2C1=O.N>>NC(=O)CN1C[C@@H]2CCCC[C@H]2C1=O,,CO,,,,test
US20100121052A1,C[C@@H](COc1cc(Nc2ncc3cc(C#C[Si](C)(C)C)ccc3n2)cc(-c2cnn(C)c2)c1)NC(=O)OC(C)(C)C>>C[C@H](N)COc1cc(Nc2ncc3cc(C#C[Si](C)(C)C)ccc3n2)cc(-c2cnn(C)c2)c1,,CCOC(C)=O,,C1COCCO1,Cl,test
US20100179322A1,COc1ccc2cc(C=O)c(=O)[nH]c2c1>>COc1ccc2cc(C)c(=O)[nH]c2c1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20120065065A1,COC(=O)c1cccnc1NS(=O)(=O)Cc1ccccc1F.O=S(=O)(OCC(F)F)C(F)(F)F>>COC(=O)c1cccnc1N(CC(F)F)S(=O)(=O)Cc1ccccc1F,,CC#N,,CCN(C(C)C)C(C)C,,test
US20100041041A1,C=O.CC(C)(C)c1ccccc1Br>>CC(C)(C)c1ccccc1CO,,C1CCOC1,,[Li]CCCC,,test
US20160152621A1,COc1cc(NC(=O)[C@H](N)CC(C)C)ccc1-c1cnco1.CS(=O)(=O)Cl>>COc1cc(NC(=O)[C@@H](CC(C)C)NS(C)(=O)=O)ccc1-c1cnco1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090069337A1,Nc1ncccc1O.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2ncccc2o1,,C1CCOC1,,,,test
US05624948,CCOC(=O)CCc1ccc(CCN2CCCNCCC2)cc1.Fc1ccc(Cn2c(Br)nc3ccccc32)cc1>>CCOC(=O)CCc1ccc(CCN2CCCN(c3nc4ccccc4n3Cc3ccc(F)cc3)CCC2)cc1,,CCCCO,,O=C([O-])O.[Na+],,test
US20150119435A1,CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=S)N1CCCC(=O)O.NCCOCCOCCC12CC3CC(CC(C3)C1)C2>>CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=S)N1CCCC(=O)NCCOCCOCCC12CC3CC(CC(C3)C1)C2,,ClCCl,ClCCl,ClCCCl,On1nnc2ccccc21,test
US20080114006A1,OCc1cnc(Cl)cc1Nc1ccccc1>>O=Cc1cnc(Cl)cc1Nc1ccccc1,O=[Mn]=O,ClCCl,,,,test
US20100029629A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCc1c[nH]c2cccnc12>>CC(C)(C)OC(=O)NCCc1c[nH]c2cccnc12,,C1CCOC1,O,CCN(CC)CC,,test
US20060035963A1,CC(=O)Oc1c2c(c3ccccc3c1OC(=O)C(C)(C)NC(=O)OC(C)(C)C)OC(C)(C)CC2.Cl>>CC(=O)Oc1c2c(c3ccccc3c1OC(=O)C(C)(C)N)OC(C)(C)CC2.Cl,,C1COCCO1,,,,test
US20040067964A1,CS(=O)(=O)c1ccc(N(S(=O)(=O)c2ccccc2)S(=O)(=O)c2ccccc2)c(I)c1>>CS(=O)(=O)c1ccc(NS(=O)(=O)c2ccccc2)c(I)c1,,C1COCCO1,,[K+].[OH-],,test
US20100087427A1,COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2O)C(C)C)ccc1OC>>COCCCOc1cc(C(=O)N(C[C@@H]2CNC[C@H]2O)C(C)C)ccc1OC,,O,,CC#N,CC#N,test
US20060135528A1,Clc1cc(N2CCN(C3CCCC3)CC2)ccn1.N>>Nc1cc(N2CCN(C3CCCC3)CC2)ccn1,[Cu],CO,,,,test
US06599917B1,C#CC1(O)CN2CCC1CC2.COCC(=O)CCc1ccc(OS(=O)(=O)C(F)(F)F)c(Cc2ccccc2)n1>>COCC(=O)CCc1ccc(C#CC2(O)CN3CCC2CC3)c(Cc2ccccc2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,CCN(CC)CC,CN(C)C=O,test
US20140088101A1,COC(=O)CN(Cc1c(C(=O)OC)cc(Br)c(=O)n1CC1CCCC1)S(=O)(=O)c1ccc(C)cc1>>COC(=O)c1ncc2c(cc(Br)c(=O)n2CC2CCCC2)c1O,,CO,,Cl,C[O-].[Na+],test
US20120029190A1,O=C(OCc1ccccc1)N1CCCC2OC2C1.[N-]=[N+]=[N-]>>[N-]=[N+]=NC1CCCN(C(=O)OCc2ccccc2)CC1O,,CO,O,[Cl-].[NH4+],,test
US20050032869A1,CC(=O)c1cc[nH]n1.N#Cc1ccc(NN)cc1>>C/C(=N\Nc1ccc(C#N)cc1)c1cc[nH]n1,,CCO,,Cl,Cl,test
US05587392,Clc1ccc(Oc2cccc3ccccc23)c(CBr)c1.c1c[nH]cn1>>Clc1ccc(Oc2cccc3ccccc23)c(Cn2ccnc2)c1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05843975,CC(C)=NOc1cc(OCc2ccccc2)ccc1C#N>>Nc1noc2cc(OCc3ccccc3)ccc12,,CCO,,Cl,,test
US20040058964A1,CSc1nccc(CBr)n1.Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)[nH]1>>CSc1nccc(Cn2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)n1,,C1CCOC1,,[H-].[Na+],,test
US20160194350A1,CC1(C)O[C@H]2C[C@@H](C=O)O[C@H]2O1.C[Mg]Br>>CC(O)[C@@H]1C[C@@H]2OC(C)(C)O[C@@H]2O1,,C1CCOC1,,,,test
US20140242028A1,CS(=O)(=O)c1ccc(O)cc1.O=[N+]([O-])c1cc(Cl)c(F)c(C(F)(F)F)c1>>CS(=O)(=O)c1ccc(Oc2c(Cl)cc([N+](=O)[O-])cc2C(F)(F)F)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110306588A1,CC(=O)Cl.c1ccc2nc(N3CCC(Oc4nccnc4N4CCNCC4)CC3)ccc2c1>>CC(=O)N1CCN(c2nccnc2OC2CCN(c3ccc4ccccc4n3)CC2)CC1,,ClCCl,,CCN(CC)CC,,test
US20160031903A1,CC(C)(CNC(=O)OCc1ccccc1)C(=O)O.CI>>CN(CC(C)(C)C(=O)O)C(=O)OCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US05206363,CC1(C)C2CCC1(C)C(C(=O)Cl)C2.CC1SC(=O)NN=C1c1ccc2c(c1)CCCN2C(=O)c1ccc2c(c1)OCO2>>CC1SC(=O)N(C(=O)C2CC3CCC2(C)C3(C)C)N=C1c1ccc2c(c1)CCCN2C(=O)c1ccc2c(c1)OCO2,,ClCCl,,CCN(CC)CC,,test
US20040110757A1,COC(=O)c1ccc(CBr)cc1.O=[N+]([O-])c1ccc(-c2cc(O)nc(-c3ccccc3)n2)cc1>>COC(=O)c1ccc(COc2cc(-c3ccc([N+](=O)[O-])cc3)nc(-c3ccccc3)n2)cc1,,CN(C)C=O,O,CCN(CC)CC,Cl,test
US20060183754A1,Cc1nc(-c2ccc(C(F)(F)F)cc2)ccc1NC(=O)OC(C)(C)C>>Cc1nc(-c2ccc(C(F)(F)F)cc2)ccc1N,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140038976A1,CCOc1ccc(S(=O)(=O)Cl)cc1.Cc1ccc2c(n1)C1CNCCN1C2=O>>CCOc1ccc(S(=O)(=O)N2CCN3C(=O)c4ccc(C)nc4C3C2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080194616A1,CC(C)(C)OC(=O)N1CCC(=O)C1.CCCCc1nc2ccccn2c(=O)c1-c1ccc2c(c1)CCN2>>CCCCc1nc2ccccn2c(=O)c1-c1ccc2c(c1)CCN2C1CCN(C(=O)OC(C)(C)C)C1,,CO,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05025025,COC(=O)CCCCBr.N#CCc1cccnc1>>COC(=O)CCCCC(C#N)c1cccnc1,,CN(C)C=O,,[H-].[Na+],,test
US20160016951A1,CC1(C)OB(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)OC1(C)C.Cn1ccc(Br)n1>>Cn1ccc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)n1,,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US04192884,ClCl.O=Cc1ccc(Cl)s1>>O=Cc1cc(Cl)c(Cl)s1,,ClC(Cl)(Cl)Cl,ClCCl,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20150111892A1,CCCCCCN=C=O.N#Cc1c[nH]c(=O)[nH]c1=O>>CCCCCCNC(=O)n1cc(C#N)c(=O)[nH]c1=O,,c1ccncc1,,O,,test
US20070049612A1,CCOC(=O)C1CC2CC(=O)CC(C1)N2.O=S(=O)(Cl)c1ccc(Cl)cc1>>CCOC(=O)C1CC2CC(=O)CC(C1)N2S(=O)(=O)c1ccc(Cl)cc1,,ClCCl,,CCN(CC)CC,,test
US05192765,CN(CCc1ccc(C(N)=O)cc1)C(C)(C)COC(c1ccccc1)c1ccccc1>>CN(CCc1ccc(CN)cc1)C(C)(C)COC(c1ccccc1)c1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070225273A1,C[C@H](OC(=O)Oc1ccc([N+](=O)[O-])cc1)C(=O)N[C@@H]1C(=O)N(CCOCc2ccccc2)c2ccccc2-c2ccccc21.NCCF>>C[C@H](OC(=O)NCCF)C(=O)N[C@@H]1C(=O)N(CCOCc2ccccc2)c2ccccc2-c2ccccc21,,c1ccncc1,,Cl,,test
US20150299120A1,CC(=O)OC1CCCC12CN(c1ccc(C#N)c(Cl)c1C)C(=O)N2.CI>>CC(=O)OC1CCCC12CN(c1ccc(C#N)c(Cl)c1C)C(=O)N2C,,C1CCOC1,O,[H-].[Na+],,test
US20110230464A1,C=CS(=O)(=O)C=C.NC1CCN(Cc2ccccc2)CC1>>O=S1(=O)CCN(C2CCN(Cc3ccccc3)CC2)CC1,,CC(C)O,,,,test
US20150307507A1,CCOC(=O)c1ccc(-c2ccc(OC)nn2)s1>>COc1ccc(-c2ccc(C(=O)O)s2)nn1,,C1CCOC1,O,[Li]O,,test
US20040110804A1,CO.CON(CCc1ccc(F)cc1)C(=O)C=C1OC(C)(C)OC1=O>>COC(=O)C(O)=CC(=O)N(CCc1ccc(F)cc1)OC,,CO,,,,test
US20080207654A1,CCCCc1nc(C)n(CC(O[Si](C)(C)C(C)(C)C)c2ccccc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nc(C)n(CC(O)c2ccccc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20090149524A1,CC(C)(C)OC(=O)CBr.CCC(=O)CC(=O)CC>>CCC(=O)C(CC(=O)OC(C)(C)C)C(=O)CC,,CN(C)C=O,,[H-].[Na+],,test
US20040014802A1,CCCC(=O)Cl.Nc1n[nH]c2c(F)c(Br)c(F)c(F)c12>>CCCC(=O)Nc1n[nH]c2c(F)c(Br)c(F)c(F)c12,,c1ccncc1,,,,test
US20040122244A1,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)O)c2)=C(C)C1=O.COc1cc(N)ccn1>>COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)Nc3ccnc(OC)c3)c2)=C(C)C1=O,,ClCCl,,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US20100292271A1,O=[N+]([O-])c1cccc2cc(S(=O)(=O)c3cccc(F)c3)cnc12>>Nc1cccc2cc(S(=O)(=O)c3cccc(F)c3)cnc12,[Fe],CC(=O)O,,,,test
US20050272709A1,Cc1cc(N)n[nH]1.Nc1nnn[nH]1.O=N[O-]>>CC1=NN=C(N)C1=NNc1nn[nH]n1,,CC(=O)O,O,O=S(=O)(O)O,,test
US20130072492A1,COC(=O)C(C)(Br)c1coc(C)n1.N#CCC#N>>COC(=O)C(C)(c1coc(C)n1)C(C#N)C#N,,CN(C)C=O,,[H-].[Na+],,test
US20130053563A1,CCC[C@@H](C)OC(=O)OC(C)Cl.COc1cc(OCCO)c(F)c(C(Nc2ccc(C(N)=NC(=O)c3ccccc3)cc2)c2nn(-c3ncccn3)c(=O)[nH]2)c1>>CCC[C@@H](C)OC(=O)OC(C)Oc1nc(C(Nc2ccc(C(N)=NC(=O)c3ccccc3)cc2)c2cc(OC)cc(OCCO)c2F)nn1-c1ncccn1,,CN(C)C=O,,O=C([O-])O.[K+],,test
US06235731B1,CC(C)(C)OC(=O)N1CCC(CBr)CC1.c1ccc(C2CCNCC2)cc1>>CC(C)(C)OC(=O)N1CCC(CN2CCC(c3ccccc3)CC2)CC1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04353827,CCc1cccc2c1C(=O)C(=O)N2.O=C(OO)c1cccc(Cl)c1>>CCc1cccc2[nH]c(=O)oc(=O)c12,,CC(=O)O,CCOC(C)=O,,,test
US20060258714A1,[N-]=[N+]=NC[C@H]1CCc2cccc(-c3ccccc3Cl)c2O1>>NC[C@H]1CCc2cccc(-c3ccccc3Cl)c2O1,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060047171A1,Cc1ccc(CCCN)cc1C>>Cc1ccc(CCCN)cc1C,,Cc1ccccc1,,Cl,[Na+].[OH-],test
US20120108566A1,NC(=O)c1cnc(Cl)cc1NCc1cccc(I)c1.OB(O)c1ccncc1>>NC(=O)c1cnc(Cl)cc1NCc1cccc(-c2ccncc2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20120245137A1,CCOC(=O)[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CO)CC1,,CCOCC,,CO,[BH4-].[Li+],test
US20120115868A1,C[Si](C)(C)Cn1cc(-c2ccccn2)nn1>>Cn1cc(-c2ccccn2)nn1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US06521643B1,CCN.COc1ccnc(-c2ccc(F)c([N+](=O)[O-])c2)c1>>CCNc1ccc(-c2cc(OC)ccn2)cc1[N+](=O)[O-],,CCO,,O,,test
US20090239860A1,Cc1cc(C(=O)O)ccc1F.O=C1CCC(=O)N1Br>>O=C(O)c1ccc(F)c(CBr)c1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20070219210A1,CCOC(=O)c1cc(-c2ccc(F)cn2)n(-c2cccnc2)n1>>O=C(O)c1cc(-c2ccc(F)cn2)n(-c2cccnc2)n1,,CCO,,[Na+].[OH-],,test
US20110003786A1,CC(=O)Nc1nc2c(s1)-c1nc(CC3CC3)sc1CC2>>Nc1nc2c(s1)-c1nc(CC3CC3)sc1CC2,,CCO,,Cl,,test
US04101579,COc1ccc(C(=O)CN(Cc2ccccc2)Cc2ccccc2)cc1C(N)=O>>COc1ccc(C(O)CN(Cc2ccccc2)Cc2ccccc2)cc1C(N)=O,,CCO,,[BH4-].[Na+],,test
US06130239,O=C1Cc2c(I)cccc2N1.O=[N+]([O-])O>>O=C1Cc2c(ccc([N+](=O)[O-])c2I)N1,,O=S(=O)(O)O,,,,test
US20150148327A1,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.Fc1ccc(Br)cn1.N#CCC(=O)O>>N#CCC(=O)Nc1ccc(Br)cn1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20050004163A1,CCNC(=O)c1ccc(C(=C2CC3CCC(C2)N3)c2ccccc2)cc1.COC(=O)N1CCN(CCCl)CC1>>CCNC(=O)c1ccc(C(=C2CC3CCC(C2)N3CCN2CCN(C(=O)OC)CC2)c2ccccc2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05087760,COC(=O)/C=C(\CCl)OC.COC(=O)CC(=O)OC>>COC(=O)/C=C(\CC(C(=O)OC)C(=O)OC)OC,,CN(C)C=O,,C[O-].[Na+],,test
US20130338140A1,CC(C)(C)OC(=O)N[C@H](CCI)c1ccc(Cl)c(Cl)c1.[C-]#N>>CC(C)(C)OC(=O)N[C@H](CCC#N)c1ccc(Cl)c(Cl)c1,,CS(C)=O,,O,,test
US05019574,CCN.O=[N+]([O-])c1c(Br)c[n+]([O-])c2ccccc12>>CCNc1c[n+]([O-])c2ccccc2c1[N+](=O)[O-],,C1CCOC1,,,,test
US20100029619A1,CC(C)(C#N)c1cccc(C(=O)O)c1.Nc1cn2nc(Oc3cccc(NC(=O)C4CC4)c3)ccc2n1>>CC(C)(C#N)c1cccc(C(=O)Nc2cn3nc(Oc4cccc(NC(=O)C5CC5)c4)ccc3n2)c1,CN(C)C=O,CC(=O)N(C)C,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US20130338142A1,CCN(CC)S(F)(F)F.CN1CCN(C(=O)OCc2ccccc2)CC1CO>>CN1CCN(C(=O)OCc2ccccc2)CC1CF,,ClCCl,,O,[Na+].[OH-],test
US05008267,Cn1c(Cl)cc(=O)n(C)c1=O.O=[N+]([O-])c1ccc(N2CCN(CCNCCO)CC2)cc1>>Cn1c(N(CCO)CCN2CCN(c3ccc([N+](=O)[O-])cc3)CC2)cc(=O)n(C)c1=O,,CCN(CC)CC,,CCO,,test
US20070208010A1,CC(C)(C)OC(=O)N[C@@H](CC(=O)NNc1nccc2ccccc12)Cc1cc(F)ccc1F>>CC(C)(C)OC(=O)N[C@H](Cc1cc(F)ccc1F)Cc1nnc2c3ccccc3ccn12,,COCCO,,,,test
US20030199440A1,COc1ccccc1CNCC(=O)OC(C)(C)C.O=S(=O)(Cl)c1ccc2c(Cl)cnc(Cl)c2c1>>COc1ccccc1CN(CC(=O)OC(C)(C)C)S(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1,,ClCCl,,CCN(CC)CC,,test
US20030125339A1,CC(C)(C)OC(=O)NCCc1ccc(NC(=O)c2cccnc2NCc2ccncc2)cc1>>NCCc1ccc(NC(=O)c2cccnc2NCc2ccncc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040186077A1,Cc1cnc(C)c(OCc2ccccc2)c1C(O)P(=O)(OC(C)(C)C)OC(C)(C)C>>Cc1cnc(C)c(O)c1C(O)P(=O)(O)O,[Pd],CO,,,,test
US20150191452A1,COc1ccc([C@@H]2CCN(C3CCN(Cc4ccc(C)c(F)c4)C3=O)C[C@H]2F)cc1F>>Cc1ccc(CN2CCC(N3CC[C@@H](c4ccc(O)c(F)c4)[C@H](F)C3)C2=O)cc1F,,ClCCl,,BrB(Br)Br,,test
US04584285,CCOC(=O)[C@H](Cc1ccc([N+](=O)[O-])cc1)N[C@@H](C)C(=O)OC(C)(C)C>>CCOC(=O)[C@H](Cc1ccc([N+](=O)[O-])cc1)N[C@@H](C)C(=O)O,,O=C(O)C(F)(F)F,,,,test
US05310897,C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1C(=O)N(CC(=O)OC(C)(C)C)[C@@H]1[C@@H](C)C(=S)c1ccc(Cl)cc1>>C[C@@H](O)[C@H]1C(=O)N(CC(=O)O)[C@@H]1[C@@H](C)C(=S)c1ccc(Cl)cc1,,ClCCl,,FB(F)F,,test
US20040171597A1,C#CCCOCCCCCCN1C[C@@H](c2ccc3c(c2)COC(C)(C)O3)OC1=O.NS(=O)(=O)c1cccc(I)c1>>CC1(C)OCc2cc([C@@H]3CN(CCCCCCOCCC#Cc4cccc(S(N)(=O)=O)c4)C(=O)O3)ccc2O1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,CCN(CC)CC,,,test
US06228979B1,CCCC(=O)C(C)(O)O.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(=O)C1(C)COC(=O)OC1,,CCN(CC)CC,,C1CCOC1,,test
US20040009995A1,COC(=O)c1cc(S(=O)(=O)c2cnc(Cl)c(Br)c2)c(SC)s1.NCc1ccccc1>>COC(=O)c1cc(S(=O)(=O)c2cnc(NCc3ccccc3)c(Br)c2)c(SC)s1,,CO,,,,test
US20160237075A1,C=CC(=O)Cl.NC(=O)c1ccc(C2CCNCC2)nc1-c1ccc(C(O)c2ccccc2)cc1>>C=CC(=O)N1CCC(c2ccc(C(N)=O)c(-c3ccc(C(O)c4ccccc4)cc3)n2)CC1,,ClCCl,,,,test
US04911748,CI.O=C1NC(Cc2ccccc2)C(=O)N1c1cc(F)ccc1F>>CN1C(=O)N(c2cc(F)ccc2F)C(=O)C1Cc1ccccc1,,CN(C)C=O,O,[H-].[Na+],,test
US20110245242A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C1CCCN1c1cccc(Nc2ncc(Cl)c(NC3CC3)n2)c1>>S=C1CCCN1c1cccc(Nc2ncc(Cl)c(NC3CC3)n2)c1,,c1ccncc1,,Cl,,test
US20090221567A1,CC(C)(C)OC(=O)N1CCC(N[C@H]2CCCC[C@@H]2CO)CC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)N1CCC(N2C(=O)OC[C@H]3CCCC[C@@H]32)CC1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20070254866A1,CCOC(=O)c1cn(C2CC2)c2c(OC)c(F)c(Cl)c([N+](=O)[O-])c2c1=O>>CCOC(=O)c1cn(C2CC2)c2c(OC)c(F)c(Cl)c(N)c2c1=O,[Fe],CC(=O)O,,,,test
US20130131043A1,CC[Mg]Br.O=CC1CCCCC1>>CCC(O)C1CCCCC1,,C1CCOC1,CCOCC,,,test
US20070111988A1,COc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc4c(c3)COC4=O)ccc2c1.Cl>>COc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc4c(c3)COC4=O)ccc2c1.Cl,,ClCCl,,CCOCC,,test
US20080242672A1,CS(=O)(=O)OCCn1ccc2c1nc(N)n1nc(-c3ccco3)nc21.Fc1ccc(S)c(F)c1>>Nc1nc2c(ccn2CCSc2ccc(F)cc2F)c2nc(-c3ccco3)nn12,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20130060041A1,CCN=C(SC)N1CC(C)(C)C=N1.Nc1ccc(S(N)(=O)=O)cc1>>CCNC(=NS(=O)(=O)c1ccc(N)cc1)N1CC(C)(C)C=N1,,CC#N,,,,test
US20140011971A1,Cc1ccccc1C#N.Cc1ccccc1I>>Cc1ccccc1C(N)c1ccccc1C,,C1CCOC1,O,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20110118234A1,CCOC(C)=O.N#CC1(c2cccc(Br)c2)CCC1.O>>O=C(O)C1(c2cccc(Br)c2)CCC1,,CCO,CCOC(C)=O,Cl,[K+].[OH-],test
US20060189601A1,COc1ccc2nccc(OS(=O)(=O)C(F)(F)F)c2n1.O=C(NCCN1CCCNCC1)OCc1ccccc1>>COc1ccc2nccc(N3CCCN(CCNC(=O)OCc4ccccc4)CC3)c2n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04857530,C#CCNc1ccc(C(C)=O)cc1.CC(C)(C)C(=O)OCn1cnc2ccc(CBr)cc2c1=O>>C#CCN(Cc1ccc2ncn(COC(=O)C(C)(C)C)c(=O)c2c1)c1ccc(C(C)=O)cc1,,CC(=O)N(C)C,,O=C([O-])[O-].[Ca+2],,test
US04873019,CCCCCCCCc1ccc(O)cc1.CCC[C@H]1CC[C@H](c2ccc(C(=O)Cl)cc2)C1>>CCCCCCCCc1ccc(OC(=O)c2ccc([C@H]3CC[C@H](CCC)C3)cc2)cc1,,Cc1ccccc1,,c1ccncc1,,test
US05010083,CI.COC(=O)CC1CC(=O)Nc2ccc(OC)cc21>>COC(=O)CC1CC(=O)N(C)c2ccc(OC)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20100016350A1,CC(C)(C)OC(=O)N1CC(O)C(N2CCCC2)C1.CCN(CC)S(F)(F)F>>CC(C)(C)OC(=O)N1C[C@H](F)[C@H](N2CCCC2)C1,,ClCCl,,,,test
US20140057902A1,O=Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>c1ccc(C(c2ccccc2)(c2ccccc2)n2cnc(-c3cnco3)c2)cc1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US06936602B1,COC(=O)C1=Cc2cc(Br)ccc2NCC1.O=CO>>COC(=O)C1=Cc2cc(Br)ccc2N(C=O)CC1,,C1CCOC1,,CC(=O)O,,test
US04939140,BrCc1nc2cc(Br)ccc2s1.CCOC(=O)Cc1n[nH]c(=O)c2ccccc12>>CCOC(=O)Cc1nn(Cc2nc3cc(Br)ccc3s2)c(=O)c2ccccc12,,CN(C)C=O,,Cl,[H-].[Na+],test
US06884868B1,BrCCCCCCCOc1ccc(Br)cc1.C[C@H]1CNC[C@@H](C)O1>>C[C@H]1CN(CCCCCCCOc2ccc(Br)cc2)C[C@@H](C)O1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090291955A1,CC(C)(C)OC(=O)N1CCC(=Cc2ccccc2C(F)(F)F)CC1>>CC(C)(C)OC(=O)N1CCC(Cc2ccccc2C(F)(F)F)CC1,[Pd],CCOC(C)=O,,,,test
US20120202785A1,CC[C@H](NC(=O)OC(C)(C)C)c1nc2cccnc2n1-c1ccccc1>>CC[C@H](N)c1nc2cccnc2n1-c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110071126A1,CC(C)(C)OC(=O)N1CC2(Cc3ccc(Br)cc3C2(NS(=O)(=O)CC[Si](C)(C)C)C(=O)O)C1.CO>>COC(=O)C1(NS(=O)(=O)CC[Si](C)(C)C)c2cc(Br)ccc2CC12CN(C(=O)OC(C)(C)C)C2,,CO,ClCCl,C[Si](C)(C)C=[N+]=[N-],,test
US03954732,C=C(C)C(C(=O)OC)N1C(=O)C(NC(=O)COc2ccccc2)C1SNCCC.Cl>>COC(=O)C1N2C(=O)C(NC(=O)COc3ccccc3)[C@H]2SCC1(C)Cl,,ClCCl,,,,test
US20030060467A1,NN.O=C(Cl)c1c(F)ccc(F)c1F>>NNC(=O)c1c(F)ccc(F)c1F,,CCO,ClCCl,CO,O,test
US20070105904A1,CO.Nc1nc(Cl)ccc1C(=O)O>>COC(=O)c1ccc(Cl)nc1N,,CO,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US05015661,C#CC1(C)CCc2c(C)c(O)c(C)c(C)c2O1.Nc1ccccc1I>>Cc1c(C)c2c(c(C)c1O)CCC(C)(C#Cc1ccccc1N)O2,,ClCCl,,,,test
US20100298336A1,CC(C)(C)[Si](C)(C)OCc1sc(Br)nc1Br>>CC(C)(C)[Si](C)(C)OCc1scnc1Br,,CCOCC,,O,[Li]CCCC,test
US20080131367A1,CC(=O)c1cc(Br)ccc1O.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CC(=O)c1cc(Br)ccc1OC(=O)c1ccc([N+](=O)[O-])cc1,,c1ccncc1,,Cl,,test
US06048842,C=CCBr.Cc1cc(O)c(C(=O)CCc2ccc3occc3c2)c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1>>C=CCOc1cc(C)cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1C(=O)CCc1ccc2occc2c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040142982A1,O=[N+]([O-])c1ccccc1S(=O)(=O)C1CCCC1>>Nc1ccccc1S(=O)(=O)C1CCCC1,,CCO,,Cl[Sn]Cl,,test
US08263607B2,C=CC(=O)Cl.c1ccc2c(c1)CCNC2C1CCCCC1>>C=CC(=O)C1(C2CCCCC2)NCCc2ccccc21,,CCN(CC)CC,ClCCl,Cl,O,test
US20060258690A1,CC(=O)N1CCC2(CC1)CCN(C(=O)OC(C)(C)C)C2.Cl>>CC(=O)N1CCC2(CCNC2)CC1.Cl,,CCOC(C)=O,,,,test
US06143764,COc1ccc(C(=O)c2ccccc2C)cc1>>Cc1ccccc1C(=O)c1ccc(O)cc1,,ClC(Cl)Cl,ClCCl,BrB(Br)Br,,test
US20120156612A1,C=C(C)C(=O)Cl.CCC1(O)CCC(C(F)(F)F)CC1>>C=C(C)C(=O)OC1(CC)CCC(C(F)(F)F)CC1,CN(C)c1ccncc1,CC(C)=O,,CCN(CC)CC,,test
US20120010182A1,COc1ccc(CN(c2nncs2)S(=O)(=O)c2cc(Cl)c(Oc3ccc(-c4cccc(C#N)c4)cc3-c3cn(C4CCCCO4)nc3[N+](=O)[O-])cc2F)c(OC)c1>>N#Cc1cccc(-c2ccc(Oc3cc(F)c(S(=O)(=O)Nc4nncs4)cc3Cl)c(-c3c[nH]nc3[N+](=O)[O-])c2)c1,,Cl,,C1COCCO1,,test
US20030212276A1,CCCCOc1cc2c(Cl)c(C#N)cnc2cc1OCCOC.COc1cc(N)c(Cl)cc1Cl>>CCCCOc1cc2c(Nc3cc(OC)c(Cl)cc3Cl)c(C#N)cnc2cc1OCCOC,,CCOCCO,,Cl,c1ccncc1,test
US20120214837A1,Cc1ccc2nc(N(C)C)c(CO)cc2c1.O=S(Cl)Cl>>Cc1ccc2nc(N(C)C)c(CCl)cc2c1.Cl,,ClCCl,,CO,,test
US20020128301A1,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)OCC(C)(C)N.O=C(Cl)OCCl>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)OCC(C)(C)NC(=O)OCCl,,ClCCl,,c1ccncc1,,test
US20140256729A1,CS(=O)(=O)Cl.NC1CCC(=O)CC1>>CS(=O)(=O)NC1CCC(=O)CC1,,C1CCOC1,CC#N,Cl,O=C([O-])[O-].[K+].[K+],test
US20030045527A1,O=S(=O)(c1cc(Cl)cc(Cl)c1)n1ccc2c(N3CCN(Cc4ccccc4)CC3)cccc21>>O=S(=O)(c1cc(Cl)cc(Cl)c1)n1ccc2c(N3CCNCC3)cccc21,,ClCCCl,,CC(Cl)OC(=O)Cl,,test
US20150315182A1,CC(C)(C)[Si](C)(C)OCc1nn2ccc(F)cc2c1I.CS(=O)(=O)c1nc(Cl)c(F)c(Cl)n1>>CC(C)(C)[Si](C)(C)OCc1nn2ccc(F)cc2c1-c1nc(Cl)c(F)c(Cl)n1,,C1CCOC1,,,,test
US20090306089A1,Cc1ncc(C2OCCO2)cc1Cl.O=C(OO)c1cccc(Cl)c1>>Cc1c(Cl)cc(C2OCCO2)c[n+]1[O-],,ClCCl,,[Na+].[OH-],,test
US20030060461A1,CC(C)(C)[Si](C)(C)Cl.COc1cc2nc(CO)[nH]c2c(OC)c1OC>>COc1cc2nc(CO[Si](C)(C)C(C)(C)C)[nH]c2c(OC)c1OC,,CN(C)C=O,,O,c1c[nH]cn1,test
US20120258952A1,CCOC=O.O=C(CCl)OCc1ccccc1>>O=CC(Cl)C(=O)OCc1ccccc1,,CCOCC,,CC(C)(C)[O-].[K+],,test
US06090836,CCCc1c(OCCCSc2ccc(CC(=O)OC)cc2Cl)ccc(C(=O)CC)c1O.NO>>CCCc1c(OCCCSc2ccc(CC(=O)OC)cc2Cl)ccc(C(CC)=NO)c1O,,CO,,Cl,CC(=O)[O-].[Na+],test
US20080004302A1,CCOc1ccc(COc2cc(N)n[nH]2)cc1OC.Cc1cc(CNc2nccc(Cl)n2)on1>>CCOc1ccc(COc2cc(Nc3ccnc(NCc4cc(C)no4)n3)n[nH]2)cc1OC,,CCO,,,,test
US20100093706A1,C[C@@H]1CC[C@H](COc2ccc(C(F)(F)F)cc2)CN1C(=O)OC(C)(C)C>>C[C@@H]1CC[C@H](COc2ccc(C(F)(F)F)cc2)CN1,,CO,,CCOCC,Cl,test
US20060046980A1,C=C(C)c1cc(C=O)ccc1F.Cc1cc(O[Si](C(C)C)(C(C)C)C(C)C)cc(C)c1Br>>C=C(C)c1cc(C(O)c2c(C)cc(O[Si](C(C)C)(C(C)C)C(C)C)cc2C)ccc1F,,C1CCOC1,CCOC(C)=O,[Li]CCCC,,test
US20080145334A1,CO[C@@]1(c2ccc(-c3ccccc3)cc2)C[C@H]2C(=O)N[C@]3(C(=O)O)C[C@H]3C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N2C1.NS(=O)(=O)C1CC1>>CO[C@@]1(c2ccc(-c3ccccc3)cc2)C[C@H]2C(=O)N[C@]3(C(=O)NS(=O)(=O)C4CC4)C[C@H]3C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N2C1,,C1CCOC1,,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US06787651B2,CC(C)(C)OC(=O)c1c(-c2cccc(OCC3CC3)c2)c2ccccc2n1Cc1ccc(F)cc1>>O=C(O)c1c(-c2cccc(OCC3CC3)c2)c2ccccc2n1Cc1ccc(F)cc1,,ClCCl,,O=CO,,test
US20140213571A1,CC(C)OB(OC(C)C)OC(C)C.C[Si](C)(C)CCOCn1ccc2cccnc21>>C[Si](C)(C)CCOCn1c(B(O)O)cc2cccnc21,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20080076745A1,CC(C)(C)OC(=O)NCCC[C@H](NC(=O)OCc1ccccc1)C(=O)NCCC[C@@H](CO)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCC[C@H](N)C(=O)NCCC[C@@H](CO)NC(=O)OC(C)(C)C,[Pd],CCO,,,,test
US20130317001A1,COC(=O)c1cc(C2CC2)c(OCC2CNC2)cc1F.O=C(Cl)c1ccccc1>>COC(=O)c1cc(C2CC2)c(OCC2CN(C(=O)c3ccccc3)C2)cc1F,,ClCCl,,CCN(CC)CC,,test
US20090209524A1,Cc1nc(N)nc(Cl)c1Cc1ccc(CO)cc1F.O=S(Cl)Cl>>Cc1nc(N)nc(Cl)c1Cc1ccc(CCl)cc1F,,ClCCl,,,,test
US20130317207A1,CCN1CCCCc2ccc(OC)cc21>>CCN1CCCCc2ccc(O)cc21,,ClCCl,,BrB(Br)Br,,test
US04410524,O=C1c2c(O)ccc(O)c2C(=O)c2c(NCCNCCO)ccc(NCCNCCO)c21.O=Cc1ccco1.c1ccccc1>>O=C1c2c(O)ccc(O)c2C(=O)c2c(NCCN3CCOC3c3ccco3)ccc(NCCN3CCOC3c3ccco3)c21,,c1ccccc1,,,,test
US20130102576A1,CN(C)c1ccncc1.ClCCl.O=C(O)CN1C(=O)C(=O)c2ccc(N3CCOCC3)cc21.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>CCOCC.O=C(CN1C(=O)C(=O)c2ccc(N3CCOCC3)cc21)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20120238541A1,N#CCBr.O=c1c(I)c(-c2ccccc2)oc2c1ccc1cn[nH]c12>>N#CCn1ncc2ccc3c(=O)c(I)c(-c4ccccc4)oc3c21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120277212A1,CC(C)(C)ON=c1cc(-c2cc3cccn3cn2)oc2ccc(CO)cc12>>CC(C)(C)ON=c1cc(-c2cc3cccn3cn2)oc2ccc(C=O)cc12,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04992433,CCOC(=O)CCC1CCN(C(=O)OCc2ccccc2)CC1>>O=C(O)CCC1CCN(C(=O)OCc2ccccc2)CC1,,CCO,,O,[K+].[OH-],test
US05436359,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.COc1c(O)c(C)c(CCCCCCCCCCOC(C)=O)c(O)c1OC>>COc1c(O)c(CCCCCCCCCCOC(C)=O)c(C)c(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1OC,,ClCCl,,c1c[nH]cn1,,test
US04309422,CCCCOP(=S)(OCCCC)Oc1cccc(C=O)c1.Cc1ccc(C(=O)NN)cc1>>CCCCOP(=S)(OCCCC)Oc1cccc(C=NNC(=O)c2ccc(C)cc2)c1,,CO,ClCCl,,,test
US20030130238A1,C=C(C(=O)OC)N(Cc1ccccc1NC(=O)c1ccccc1)S(=O)(=O)c1ccc(OC)cc1>>COC(=O)C1CN(C(=O)c2ccccc2)c2ccccc2CN1S(=O)(=O)c1ccc(OC)cc1,,CO,,O=C([O-])O.[Na+],,test
US20160207929A1,CC(Cl)C(=O)Cl.Nc1cccc(F)c1C(=O)Nc1ccccc1>>CC(Cl)C(=O)Nc1cccc(F)c1C(=O)Nc1ccccc1,,ClCCl,,,,test
US04454120,CC(C)(C)OC(=O)N[C@H](CO)C(=O)NCCCc1ccccc1.Cl>>Cl.N[C@H](CO)C(=O)NCCCc1ccccc1,,CC(=O)O,,N#N,,test
US20040157881A1,COC(=O)c1ccc(-c2nc(-c3ccc(C(F)(F)F)cc3)no2)c([N+](=O)[O-])c1>>O=C(O)c1ccc(-c2nc(-c3ccc(C(F)(F)F)cc3)no2)c([N+](=O)[O-])c1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20120083469A1,Cl.NC(CCCCB(O)O)(C(=O)O)C1CCNCC1.O=C=NCc1ccc(Cl)cc1>>Cl.NC(CCCCB(O)O)(C(=O)O)C1CCN(C(=O)NCc2ccc(Cl)cc2)CC1,,CN(C)C=O,Cl,CCN(CC)CC,,test
US20010051631A1,CCOC(=O)c1cccc2ncc([N+](=O)[O-])n12>>CCOC(=O)c1cccc2ncc(N)n12,[Pd],CCO,,,,test
US05079358,O=C(O)c1ccccc1Cl.O=C(O)c1n[nH]c2ccccc12>>O=C(O)c1ccccc1-n1nc(C(=O)O)c2ccccc21,O=[Cu],O=[N+]([O-])c1ccccc1,,O,O=C([O-])[O-].[K+].[K+],test
US20110172214A1,CC(C)C[C@H](N)/C=C/CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C.O=P(Cl)(c1ccccc1)c1ccccc1>>CC(C)C[C@@H](/C=C/CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)NP(=O)(c1ccccc1)c1ccccc1,,Cl,ClCCl,CCN(CC)CC,,test
US20050192458A1,COc1ccc(C(c2ccc(OC)cc2)N2S(=O)OCC2(C)C(=O)OC(C)(C)C)cc1.O>>COc1ccc(C(c2ccc(OC)cc2)N2C(C)(C(=O)OC(C)(C)C)COS2(=O)=O)cc1,,CC#N,,,,test
US20110178091A1,CCc1c(C(=O)O)c(C)n(C)c1-c1ccccc1>>Cc1c(C(=O)O)cc(-c2ccccc2)n1C,,CCO,,[Na+].[OH-],,test
US20080039457A1,Fc1ccc(-c2cnc(Cl)nn2)cc1.NN>>NNc1ncc(-c2ccc(F)cc2)nn1,,c1ccncc1,,O,,test
US20160159815A1,CO.COC(=O)c1ccc(OCC(C)(C)F)c(Cl)n1>>COc1nc(C(=O)O)ccc1OCC(C)(C)F,,C1COCCO1,CO,O,C[O-].[Na+],test
US20050131017A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C[C@@H]1OC(C)(C)N(C(=O)OCc2ccccc2)[C@H]1Cc1ccc(-c2cccnc2)cc1>>N[C@@H](Cc1ccccc1)C[C@H](O)[C@H](Cc1ccc(-c2cccnc2)cc1)NC(=O)OCc1ccccc1,,CO,,Cl,,test
US20130296555A1,NC(=O)c1noc([C@@H]2CC[C@@H]3CN2C(=O)N3OCc2ccccc2)n1>>NC(=O)c1noc([C@@H]2CC[C@@H]3CN2C(=O)N3O)n1,[Pd],C1CCOC1,CO,,,test
US20160272588A1,CCc1c(-c2ccc(OC)cc2F)cnc(N)c1Br.OB(O)c1ccc(O)cc1>>CCc1c(-c2ccc(OC)cc2F)cnc(N)c1-c1ccc(O)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20140045873A1,CI.Cc1cc(O)cc(-c2cccc(Br)n2)n1>>COc1cc(C)nc(-c2cccc(Br)n2)c1,,CC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130317001A1,CC(C)(C)OC(=O)c1cc(Cl)c(F)cc1F.OCC1CCN(C(c2ccccc2)c2ccccc2)CC1>>O=C(O)c1cc(Cl)c(OCC2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1F,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20050148627A1,CCOC(=O)/C=C/C(F)(F)F.O=Cc1ccc(F)cc1O>>CCOC(=O)C1=Cc2ccc(F)cc2OC1C(F)(F)F,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20150111885A1,CI.Cn1cc(Br)cc(NC(=O)OC(C)(C)C)c1=O>>CN(C(=O)OC(C)(C)C)c1cc(Br)cn(C)c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20080125431A1,O=C1OC2(CCCCC2)CN1Cc1ccc(C2=CCCCC2)cc1>>O=C1OC2(CCCCC2)CN1Cc1ccc(C2CCCCC2)cc1,[Pd],CCO,,,,test
US20100197683A1,CC(C)(O)COC1CCC(=O)CC1.Nc1nc[nH]n1>>CC(C)(O)COC1CCC(Nc2nc[nH]n2)CC1,,CC(=O)O,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090176843A1,Br[Mg]Cc1ccccc1.Cc1cccc(C(=O)c2cncn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1C>>Cc1cccc(C(O)(Cc2ccccc2)c2cncn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1C,,ClCCl,,,,test
US20070244131A1,Cl.O=[N+]([O-])C=Cc1ccc(OC(F)(F)F)cc1>>Cl.NCCc1ccc(OC(F)(F)F)cc1,[Pd],CO,,[H][H],,test
US20060004084A1,N#Cc1ccc2c(c1)COC2=C1C(=O)Nc2ccccc21>>NCc1ccc2c(c1)COC2=C1C(=O)Nc2ccccc21,,C1CCOC1,,B,CSC,test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCCC1.Oc1cc2cc[nH]c2cc1F>>COc1cc2c(Oc3cc4cc[nH]c4cc3F)ncnc2cc1OCCCN1CCCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060100283A1,CS(=O)(=O)Nc1cc(OC[C@@H](O)CN(Cc2ccccc2)[C@@H]2CC[C@@H](c3ccc(-c4ccccc4)cc3)CC2)ccc1OCc1ccccc1>>CS(=O)(=O)Nc1cc(OC[C@@H](O)CN[C@@H]2CC[C@@H](c3ccc(-c4ccccc4)cc3)CC2)ccc1O,[Pd],CCO,,,,test
US20010056100A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1ccc(-c2ccc3[nH]ccc3c2)cc1>>CC(C)(C)OC(=O)n1ccc2cc(-c3ccccc3)ccc21,CN(C)c1ccncc1,CC#N,,CCOC(C)=O,,test
US20070123690A1,Cc1c(Br)c(=O)oc2cc(N(c3ccc(Br)cc3)c3ccc(Br)cc3)ccc12>>Cc1cc(=O)oc2cc(N(c3ccc(Br)cc3)c3ccc(Br)cc3)ccc12,[Zn],CC(=O)O,,,,test
US20060142581A1,CC(C)(C)OC(=O)NCCC(=O)Nc1ccc(C#CCCNC(=O)OCc2ccccc2)cc1>>CC(C)(C)OC(=O)NCCC(=O)Nc1ccc(CCCCNC(=O)OCc2ccccc2)cc1,[Pd],COCCOC,,,,test
US20090036492A1,CCCOc1cc(C)c(C=O)c2ccccc12.COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>CCCOc1cc(C)c(CNC(=O)c2c(OC)cc(O)c3c2OC2=CC(O)=C(C(C)=O)C(=O)[C@]23C)c2ccccc12,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20060111585A1,CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc(S(N)(=O)=O)cc1.O=C=NC1CCCCC1>>CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc(S(=O)(=O)NC(=O)NC2CCCCC2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100190688A1,CC(NC(=O)C1CC(=O)C2c3c(ccn3C1)CCC2NC(=O)OCC1c2ccccc2-c2ccccc21)c1ccc2ccccc2c1>>CC(NC(=O)C1CC(=O)C2c3c(ccn3C1)CCC2N)c1ccc2ccccc2c1,,ClCCl,,CCNCC,,test
US20150119362A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Clc1cnn(Cc2ccc(CBr)cc2)c1>>CC1(C)OB(Cc2ccc(Cn3cc(Cl)cn3)cc2)OC1(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20070259881A1,CCOCc1nc2c(N)nc3cc(Br)ccc3c2n1CC1COC(C)(C)O1>>Br.CCOCc1nc2c(N)nc3ccccc3c2n1CC1COC(C)(C)O1,[Pd],,,,,test
US20150045378A1,COC(=O)c1cc(Cl)c(Br)cn1>>O=C(O)c1ccc(Br)c(Cl)n1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20160207930A1,C=CCC1(CC=C)C[C@H]2[C@H](c3cn(Cc4ccccc4)nc3C)NCCN2C1=O.CCc1cc(C(C)NC)cc(C(F)(F)F)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>C=CCC1(CC=C)C[C@H]2[C@H](c3cn(Cc4ccccc4)nc3C)N(C(=O)N(C)[C@H](C)c3cc(CC)cc(C(F)(F)F)c3)CCN2C1=O,CN(C)c1ccncc1,CCOC(C)=O,,,,test
US04341775,CC(C)(C)OC(=O)NCCON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3CCO)CS[C@H]12)c1csc(NC=O)n1>>NCCON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3CCO)CS[C@H]12)c1csc(N)n1,,CO,,Cl,,test
US20160194350A1,CO.Cc1ccc(S(=O)(=O)OC[C@@H](O)[C@@H]2C[C@H]3OC(C)(C)O[C@H]3O2)cc1>>COC[C@H](O)[C@@H]1C[C@H]2OC(C)(C)O[C@H]2O1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04002755,CCOC(C)([O-])[O-].COc1ccc2nc(NN)nc(-c3ccccc3)c2c1>>COc1ccc2c(c1)c(-c1ccccc1)nc1nnc(C)n12,,CCO,,O=S(=O)(O)O,,test
US20060089354A1,CCOC(=O)C(CCl)Cc1nc(O)c2ccc(-c3ncccc3C(F)(F)F)cc2n1.O=P(Cl)(Cl)Cl>>CCOC(=O)CCc1nc(Cl)c2ccc(-c3ncccc3C(F)(F)F)cc2n1,,ClC(Cl)Cl,,Cc1cccc(C)n1,,test
US20110028445A1,C[C@@H]1[C@H]2Cc3cc(Br)c(O)cc3[C@]1(C)CCN2C(=O)C(F)(F)F.N#C[Cu]C#N>>C[C@@H]1[C@H]2Cc3cc(C#N)c(O)cc3[C@]1(C)CCN2C(=O)C(F)(F)F,,CN1CCCC1=O,,O,,test
US05326863,COC(=O)[C@@H]1NC(=O)[C@H]1CCCNC(=NC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1.CS(=O)(=O)Cl>>COC(=O)[C@H]1[C@H](CCCNC(=NC(=O)OCc2ccccc2)NC(=O)OCc2ccccc2)C(=O)N1S(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20060079533A1,CCOC(=O)C=Cc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2O)cc1>>CCOC(=O)CCc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2O)cc1,[Pd],CCO,,,,test
US20050026973A1,CCOC(=O)C(C)(C)Oc1ccc(OCCn2c(=O)sc3cc(C(=NO)c4ccccc4)ccc32)cc1>>CC(C)(Oc1ccc(OCCn2c(=O)sc3cc(C(=NO)c4ccccc4)ccc32)cc1)C(=O)O,,CCO,,Cl,[K+].[OH-],test
US20050245529A1,C/C(=C\CCl)c1ccc(Br)cc1.CC1CCNCC1>>C/C(=C\CN1CCC(C)CC1)c1ccc(Br)cc1,,CN(C)C=O,,,,test
US05102904,CC#N.COn1cc(C(=O)O)cc1-c1ccc(Cl)cc1.O=C=NS(=O)(=O)Cl>>COn1cc(C#N)c(C#N)c1-c1ccc(Cl)cc1,,CN(C)C=O,O,,,test
US20080287394A1,COc1c2n(c3c(CO)nn(Cc4ccc(F)cc4)c(=O)c13)CCN(C)C2=O>>CN1CCn2c(c(O)c3c(=O)n(Cc4ccc(F)cc4)nc(CO)c32)C1=O,,ClCCl,,BrB(Br)Br,CO,test
US20080280948A1,COc1cc(N)ccc1-n1cnc(C)c1.O=c1ccccn1C(=S)n1ccccc1=O>>COc1cc(N=C=S)ccc1-n1cnc(C)c1,,ClCCl,,,,test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCCCS(C)(=O)=O.Oc1ccc2cccnc2c1>>COc1cc2c(Oc3ccc4cccnc4c3)ncnc2cc1OCCCS(C)(=O)=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060194801A1,ClCC1CO1.O=[N+]([O-])c1ccc(O)c(O)c1>>O=[N+]([O-])c1ccc2c(c1)OC(CO)CO2,,CN(C)C=O,O,O=C([O-])O.[Na+],,test
US20050143443A1,CC(=O)Cl.CCOC(=O)c1cc(CNc2ccc(Cl)cc2)c[nH]1>>CCOC(=O)c1cc(CN(C(C)=O)c2ccc(Cl)cc2)c[nH]1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120252805A1,Cc1cc(NS(=O)(=O)c2cccc(Cl)c2)c2c(C)c(Br)sc2n1.OB(O)c1cc[nH]n1>>Cc1cc(NS(=O)(=O)c2cccc(Cl)c2)c2c(C)c(-c3cc[nH]n3)sc2n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20150175584A1,COc1ccc2c(Cl)ncnc2c1OC.N[C@@H]1CCOC1>>COc1ccc2c(N[C@@H]3CCOC3)ncnc2c1OC,,CN(C)C=O,,Cl,,test
US20020156311A1,C=CCBr.CC(=O)Oc1cccc(O)c1>>C=CCOc1cccc(OC(C)=O)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US05733913,CSc1ncc(C=O)c(N)n1.N#CCc1c(Cl)cccc1Cl>>CSc1ncc2cc(-c3c(Cl)cccc3Cl)c(N)nc2n1,,CN(C)C=O,,[H-].[Na+],,test
US20060241127A1,Nc1ccc(Oc2ccnc3[nH]ccc23)cc1F.Nc1nc(Cl)cc(-c2ccncc2)n1>>Nc1nc(Nc2ccc(Oc3ccnc4[nH]ccc34)cc2F)cc(-c2ccncc2)n1,,O,,Cl,O=C([O-])O.[Na+],test
US07235559B1,C1CNCCN1.N#Cc1ccc(F)cc1>>N#Cc1ccc(N2CCNCC2)cc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US05883262,Fc1ccccn1.OCCOc1ccc(Cn2cccn2)cc1Cl>>Clc1cc(Cn2cccn2)ccc1OCCOc1ccccn1,,CN(C)C=O,,[H-].[Na+],,test
US05506190,CC(N)c1ccccc1.O=C1C2=C(CCCC2)C(=O)N1c1cc(OC2CCCC2)c(Cl)cc1F>>CC(NC(=O)C1=C(C(=O)Nc2cc(OC3CCCC3)c(Cl)cc2F)CCCC1)c1ccccc1,,c1ccccc1,,CCN(CC)CC,,test
US05543078,CCCCCC[C@H](C)Oc1ccc(C)c([N+](=O)[O-])c1.O=C1CCC(=O)N1Br>>CCCCCC[C@H](C)Oc1ccc(CBr)c([N+](=O)[O-])c1,,ClCCl,,,,test
US04874775,CCCCCC(C)NCc1cccnc1.CS(=O)(=O)Cl>>CCCCCC(C)N(Cc1cccnc1)S(C)(=O)=O,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20030195176A1,CC(C)(O)COC(C)(C)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>CC(C)(O)COC(C)(C)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090036453A1,C=C(OCCCC)c1cn(COCC[Si](C)(C)C)c2cnn(COCC[Si](C)(C)C)c(=O)c12.O=C1CCC(=O)N1Br>>C[Si](C)(C)CCOCn1ncc2c(c(C(=O)CBr)cn2COCC[Si](C)(C)C)c1=O,,C1CCOC1,,O,,test
US20070105904A1,C#Cc1ccc(N)nc1N.Cc1cccc(OCc2ccc(CC(Cl)=NO)cc2)n1>>Cc1cccc(OCc2ccc(Cc3cc(-c4ccc(N)nc4N)on3)cc2)n1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,O,test
US04256759,Cn1cccc1C(=O)CC#N.O=C=Nc1c(Cl)cccc1Cl>>Cn1cccc1C(=O)C(C#N)C(=O)Nc1c(Cl)cccc1Cl,,Cc1ccccc1,,CCN(CC)CC,,test
US20060142323A1,Nc1c2c(nc3ccccc13)CCCC2.O=C1c2ccccc2C(=O)N1CCCCCCCCBr>>O=C1c2ccccc2C(=O)N1CCCCCCCCNc1c2c(nc3ccccc13)CCCC2,,CS(C)=O,,[K+].[OH-],,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4cccc(OC)c4)nc(Cl)c3n2)cc1.Nc1cc(C2CC2)[nH]n1>>COc1cccc(-c2nc(Nc3cc(C4CC4)[nH]n3)c3[nH]ncc3n2)c1,C1COCCO1,CO,,Cl,,test
US20080181866A1,CN1CCC(=O)CC1.N[C@@H](CS)C(=O)O>>CN1CCC2(CC1)N[C@H](C(=O)O)CS2,,CCO,O,,,test
US20100076027A1,COC(=O)c1ccc(S(=O)(=O)CC(c2c3c(nn2-c2ccc(Cl)cc2)CCCC3)C2CCCCC2)cc1>>O=C(O)c1ccc(S(=O)(=O)CC(c2c3c(nn2-c2ccc(Cl)cc2)CCCC3)C2CCCCC2)cc1,,CO,O,[Na+].[OH-],,test
US06057452,COC(=O)C(O)C(NC(=O)NC(C)(C)C)c1ccccc1.COc1ccc(C(OC)OC)c(OC)c1>>COC(=O)[C@@H]1OC(c2ccc(OC)cc2OC)N(C(=O)NC(C)(C)C)[C@H]1c1ccccc1,,C1CCOC1,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20100152163A1,CC(=CBr)c1ccccc1F.CN1CCc2[nH]c3ccc(Cl)cc3c2CC1>>C/C(=C\n1c2c(c3cc(Cl)ccc31)CCN(C)CC2)c1ccccc1F,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20110144066A1,CCCCCCCCCCCCc1ccc(S(=O)(=O)Nc2nnc(CCCCCNC)s2)cc1.O=[N+]([O-])c1ccc(Cl)c2nonc12>>CCCCCCCCCCCCc1ccc(S(=O)(=O)Nc2nnc(CCCCCN(C)c3ccc([N+](=O)[O-])c4nonc34)s2)cc1,,CO,,O=C([O-])O.[Na+],,test
US20050197338A1,Cc1cc(-n2cc(NC(N)=O)c(C(N)=O)n2)ccc1I.OB(O)c1ccccc1O>>Cc1cc(-n2cc(NC(N)=O)c(C(N)=O)n2)ccc1-c1ccccc1O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04962103,CC(=O)S[C@H]1C[C@@H](CO)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1.CCOC(=O)Cl>>CCOC(=O)OC[C@@H]1C[C@H](SC(C)=O)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1,,ClCCl,,CCN(CC)CC,,test
US04233307,CN1C(=O)C2(CCNCC2)c2ccccc21.ClCCOc1ccccc1>>CN1C(=O)C2(CCN(CCOc3ccccc3)CC2)c2ccccc21.Cl,,CN(C)C=O,O,[I-].[K+],,test
US20100016279A1,Cn1nccc1CCO.Oc1ccc(C2CCNCC2)cc1>>Cn1nccc1CCOc1ccc(C2CCNCC2)cc1,,ClCCl,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070276000A1,CCC1CO1.COc1cccc([Mg]Br)c1>>CCC(O)Cc1cccc(OC)c1,[Cu]I,C1CCOC1,,,,test
US20030028022A1,BrCc1ccccc1CBr.O=C1c2ccccc2C(=O)N1O>>O=C1c2ccccc2C(=O)N1OCc1ccccc1CBr,,CN(C)C=O,,CCN(CC)CC,,test
US20090054407A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc3cc[nH]c3c2)CC1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc3ccn(C(=O)OC(C)(C)C)c3c2)CC1,CN(C)c1ccncc1,CC#N,,,,test
US20070032437A1,COC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)OC(C)(C)C)C(C)C>>CC(C)[C@H](NC(=O)[C@H](C)NC(=O)OC(C)(C)C)C(=O)O,,CC(C)=O,,[Na+].[OH-],,test
US20150210635A1,CC(C)(C)OC(=O)NC(C)(C)C(=O)O.COC(=O)C12CC3CC(C1)C(N)C(C3)C2>>COC(=O)C12CC3CC(C1)C(NC(=O)C(C)(C)NC(=O)OC(C)(C)C)C(C3)C2,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20110105533A1,CC(C)S(=O)(=O)N[C@@H]1CCCC[C@@H]1Oc1ccc(Br)nc1>>CC(C)S(=O)(=O)N[C@H]1CCCC[C@H]1Oc1ccc(Br)nc1,,CO,,O=C=O,,test
US20130217702A1,O=C(O)c1cc2ccccc2[nH]1.O=C1CCC(=O)N1Cl>>O=C(O)c1[nH]c2ccccc2c1Cl,,CC#N,,,,test
US20100144852A1,CC(C)(C)[Si](C)(C)Cl.OCCCCCCCCCBr>>CC(C)(C)[Si](C)(C)OCCCCCCCCCBr,,ClCCl,,c1c[nH]cn1,,test
US20080019915A1,COC(=O)C(CC[N+](=O)[O-])c1cccc(Br)c1>>COC(=O)C(CCN)c1cccc(Br)c1,,CO,,[BH4-].[Na+],,test
US20130178460A1,CCc1cccc(NC(=O)c2csc3cnc(N[C@@H]4CCOC[C@@H]4NC(=O)OC(C)(C)C)nc23)n1>>CCc1cccc(NC(=O)c2csc3cnc(N[C@@H]4CCOC[C@@H]4N)nc23)n1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20050020587A1,COc1cccc(SC)c1>>CSc1cccc(O)c1,,Br,CC(=O)O,O,,test
US20060276523A1,BrCc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1.CCCCc1nc(Cl)c(C(=O)OCCCO[N+](=O)[O-])[nH]1>>CCCCc1nc(Cl)c(C(=O)OCCCO[N+](=O)[O-])n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,CC(=O)N(C)C,,CC(C)(C)[O-].[K+],,test
US20130102778A1,Cc1onc(-c2ccc(F)cc2)c1CO.N#Cc1ccc(Cl)nc1>>Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C#N)cn1,,C1CCOC1,O,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US04973429,CCCCCCCCCCCCCCCCN.O=[N+]([O-])c1ccc(Cl)nc1>>CCCCCCCCCCCCCCCCNc1ccc([N+](=O)[O-])cn1,,CN(C)C=O,ClC(Cl)Cl,O,O=C([O-])O.[Na+],test
US20060270713A1,CC(C)(C)OC(=O)N1CC[C@H](NCc2ccc(Cl)cc2Cl)C1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CC[C@H](N(Cc2ccc(Cl)cc2Cl)C(=O)C(F)(F)F)C1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US04344959,C=[N+]=[N-].COC(C)(C)CCCC(C)CC(O)CC(=O)C1COC(=O)C1>>COC(/C=C(/O)CC(C)CCCC(C)(C)OC)=C1COC(=O)C1,,CCOCC,,,,test
US20040162352A1,CCOC=O.CN(C)C(=O)Sc1ccc2c(c1)CC(N)C2>>CN(C)C(=O)Sc1ccc2c(c1)CC(NC=O)C2,,ClC(Cl)Cl,,,,test
US20100120760A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(O)c(C/C=C/C(=O)OC)c12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc3c(c12)CC(CC(=O)OC)O3,,CO,,O=C([O-])[O-].[Na+].[Na+],,test
US20150299121A1,C[C@H]1CN(Cc2cccc([N+](=O)[O-])c2Cl)C[C@@H](C)N1.O=C(Cl)C1CCCC1>>C[C@H]1CN(Cc2cccc([N+](=O)[O-])c2Cl)C[C@@H](C)N1C(=O)C1CCCC1,,ClCCl,,CCN(CC)CC,,test
US20050113283A1,CCOC(=O)CC(=O)C(F)(F)F.Nc1cc(-c2ccccc2Br)n[nH]1>>O=C(CC(=O)C(F)(F)F)Nc1cc(-c2ccccc2Br)n[nH]1,,CC(=O)O,,,,test
US04585781,BrBr.CC(=O)OCCn1cnnn1>>CC(=O)OCCn1nnnc1Br,,CC(=O)O,ClC(Cl)Cl,,,test
US20090137557A1,COc1ccccc1-c1nc2c(c(=O)n1CCc1ccccc1)C(C)(C)CCC2>>CC1(C)CCCc2nc(-c3ccccc3O)n(CCc3ccccc3)c(=O)c21,,ClCCl,,BrB(Br)Br,CO,test
US20110092539A1,COC(=O)c1ccc2c(c1)CCC2NS(=O)(=O)C(C)C>>CC(C)S(=O)(=O)NC1CCc2cc(CO)ccc21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140031360A1,CC(C)(C)OC(=O)N1CCC[C@@H](Oc2cncc(-c3nn(C4CCCCO4)c4ccc(-c5ccnc(Cl)n5)cc34)n2)C1.NC1CC1>>CC(C)(C)OC(=O)N1CCC[C@@H](Oc2cncc(-c3nn(C4CCCCO4)c4ccc(-c5ccnc(NC6CC6)n5)cc34)n2)C1,,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US20100190747A1,CCCCI.O=c1c2cc[nH]c2[nH]c(=S)n1-c1ccc(OCC(F)(F)F)cc1>>CCCCSc1nc2[nH]ccc2c(=O)n1-c1ccc(OCC(F)(F)F)cc1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20080318923A1,COC(=O)COC1(c2ccccc2OC)C(=O)Nc2ccc(Cl)cc21>>COc1ccccc1C1(OCC(=O)O)C(=O)Nc2ccc(Cl)cc21,,CO,,[Na+].[OH-],,test
US20080139523A1,C=CCCN.C=CCOc1ccc(C(CC(=O)N=C(Cc2cc(Cl)c(NC(=O)CBr)c(Cl)c2)NC(=O)OC(C)(C)C)=NOCC)cc1>>C=CCCNCC(=O)Nc1c(Cl)cc(CC(=NC(=O)CC(=NOCC)c2ccc(OCC=C)cc2)NC(=O)OC(C)(C)C)cc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20150210720A1,CC(C)Oc1nc(N2C[C@H]3NCC[C@H]3C2)ccc1NC(=O)c1coc2c1C(=O)NC(C)(C)C2.OCCBr>>CC(C)Oc1nc(N2C[C@@H]3[C@@H](CCN3CCO)C2)ccc1NC(=O)c1coc2c1C(=O)NC(C)(C)C2,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,,test
US20040034004A1,BrBr.CC(C)C(=O)c1ccc2c(c1)C(C)(C)CO2>>CC(C)C(=O)c1cc(Br)c2c(c1)C(C)(C)CO2,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20120108619A1,COC(OC)N(C)C.Nc1cc2cc(Br)ccc2cn1>>CNc1cc2cc(Br)ccc2cn1,,CN(C)C=O,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US07053099B1,O=C(O)n1ccnc1.[NH-]c1c(Nc2c(F)cccc2F)cccc1Oc1ccccc1>>O=C1NCc2c(Oc3ccccc3)cccc2N1c1c(F)cccc1F,,C1CCOC1,,,,test
US03998955,CCCCc1c(Cl)cc(COC(C)=O)nc1Cl>>CCCCc1c(Cl)cc(CO)nc1Cl,,Cl,,,,test
US20160002221A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(CN)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>CC(C)(C)OC(=O)NCC(C)(C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1,,ClCCl,,CCN(CC)CC,,test
US20110237590A1,O=Cc1ccccc1.OC1CCCNC1>>OC1CCCN(Cc2ccccc2)C1,,CC(=O)O,Cc1ccccc1,O=C([O-])O.[Na+],,test
US04201790,CC(C)N.Cc1ccc(C(=O)c2c(C)cc(C)cc2OCC2CO2)cc1>>Cc1ccc(C(=O)c2c(C)cc(C)cc2OCC(O)CNC(C)C)cc1,,CO,,,,test
US20130109679A1,CCOC(=O)c1ccc2cc3n(c2c1)[C@@H](C)[C@H](C)NC3=O>>C[C@@H]1NC(=O)c2cc3ccc(C(=O)O)cc3n2[C@H]1C,,CCO,,Cl,[Na+].[OH-],test
US04980509,CCN.Cc1ccc(S(=O)(=O)Cl)cc1>>CCNS(=O)(=O)c1ccc(C)cc1,,O,,,,test
US20060148856A1,O=[N+]([O-])c1cc(C2CC2)ccc1Nc1cccc(-c2ccon2)c1>>Nc1cc(C2CC2)ccc1Nc1cccc(-c2ccon2)c1,[Pd],CCO,,,,test
US20090247524A1,COc1ccccc1S.CS(=O)c1nc(N)nc(C2(C#N)c3cccc4c3C(=CC2Cl)COC4)n1>>COc1ccccc1Sc1nc(N)nc(C2(C#N)c3cccc4c3C(=CC2Cl)COC4)n1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US04358406,C[C@H](CCCC(O)(C(F)(F)F)C(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C>>C[C@H](CCCC(O)(C(F)(F)F)C(F)(F)F)[C@H]1CC[C@H]2[C@@H]3C=CC4=CC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C,,C1COCCO1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20070190359A1,Cc1cccc2cnc3c(c12)C(=O)CC=C3.O=P(Cl)(Cl)Cl>>Cc1cccc2c(Cl)nc3ccccc3c12,,Cc1ccccc1,,ClP(Cl)(Cl)(Cl)Cl,,test
US20040138286A1,CCOC(=O)C1CCCNC1.ClCc1ccccc1>>CCOC(=O)C1CCCN(Cc2ccccc2)C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120129840A1,CCCC(C(=O)OC)c1c(CC)nc(N2CCCCC2)[nH]c1=O.O=P(Cl)(Cl)Cl>>CCCC(C(=O)OC)c1c(Cl)nc(N2CCCCC2)nc1CC,,Cc1ccccc1,,CN(C)c1ccccc1,,test
US04333942,CN1CCC(Cc2ccccc2)(Oc2ccc(N)cc2)CC1>>CN1CCC(Cc2ccccc2)(Oc2ccccc2)CC1,,CCO,,Cl,,test
US20150166486A1,COC(=O)[C@@H]1CC[C@@H](C(C)=O)CC1.Clc1cnc(I)nc1>>COC(=O)[C@@H]1CC[C@@H](C(C)(O)c2ncc(Cl)cn2)CC1,,C1CCOC1,,[Li]CCCC,,test
US20130165436A1,Cc1cc(N2CCOc3ccc(O[C@H]4CCNC4)cc32)cnc1S(C)(=O)=O.O=C(Cl)C1CCOCC1>>Cc1cc(N2CCOc3ccc(O[C@H]4CCN(C(=O)C5CCOCC5)C4)cc32)cnc1S(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US05563137,CC(=O)OC[C@H]1O[C@@H]2[C@@H](Sc3ccc(Cl)cc3N2C)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>CN1c2cc(Cl)ccc2S[C@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]21,,CO,,N,,test
US20150376170A1,CC(C)(C)OC(=O)N1c2ccc(Cl)cc2OCC1O.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)CC1COc2cc(Cl)ccc2N1C(=O)OC(C)(C)C,,C1CCOC1,,O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20060167044A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CCOP(=O)(Cc1ccc(F)cc1)OCC>>CC(C)(C)OC(=O)N1CCC(=Cc2ccc(F)cc2)CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20050143372A1,COC(=O)C(Cc1ccc(Cl)cc1)N(C(C)=O)C1CCN(Cc2cccc(Oc3ccccc3OC)c2)CC1>>COc1ccccc1Oc1cccc(CN2CCC(N(C(C)=O)C(Cc3ccc(Cl)cc3)C(=O)O)CC2)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20090238761A1,CCOC(=O)C(=O)Cc1cccc(OC)c1[N+](=O)[O-]>>CCOC(=O)c1cc2cccc(OC)c2[nH]1,[Pd],CCO,,,,test
US20090074675A1,COc1ccc(F)cc1C(C)(C)C[C@@](O)(CN[C@H](C)c1ccccc1)C(F)(F)F>>COc1ccc(F)cc1C(C)(C)C[C@@](O)(CN)C(F)(F)F,[Pd],CCO,,,,test
US20100184758A1,CC(C)(C)OC(=O)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccc(F)cc2)c[nH]1.Cn1cc(C=O)cn1>>Cn1cc(C2N[C@@H](c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1,O=C(O)C(F)(F)F,CO,,N,,test
US20150148340A1,CCOC=C(C(=O)NC(=O)OCC)C(=O)OCC.CN1C(=O)C(O)(C(F)(F)F)c2cc(N)ccc21>>CCOC(=O)c1cn(-c2ccc3c(c2)C(O)(C(F)(F)F)C(=O)N3C)c(=O)[nH]c1=O,,CCO,O,Cl,CC(C)(C)[O-].[K+],test
US20140094473A1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=CC1CCC1>>CCOC(=O)/C=C/C1CCC1,,ClCCl,,,,test
US20070191370A1,Cc1ccc(C(Oc2cc(Cl)nc(N)n2)C(F)(F)F)cc1.N[C@@H](Cc1ccc(B(O)O)cc1)C(=O)O>>Cc1ccc(C(Oc2cc(-c3ccc(CC(N)C(=O)O)cc3)nc(N)n2)C(F)(F)F)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US04656170,CC(=O)C(C)CC(=O)O.CC(=O)Nc1ccc(C=O)cc1>>CC(=O)Nc1ccc(C=CC(=O)C(C)CC(=O)O)cc1,,C1CCOC1,Cc1ccccc1,C1CCNCC1,,test
US20150152048A1,COC(=O)Nc1ccc(-c2cnc([C@@H]3C[C@H](C4CCN(S(C)(=O)=O)CC4)CN3C(=O)OC(C)(C)C)[nH]2)cc1.O=C1CCC(=O)N1Cl>>COC(=O)Nc1ccc(-c2[nH]c([C@@H]3C[C@H](C4CCN(S(C)(=O)=O)CC4)CN3C(=O)OC(C)(C)C)nc2Cl)cc1,,CC#N,CN(C)C=O,,,test
US20060111375A1,COc1cc2c(Oc3cc4cccnc4nc3C)ccnc2cc1O.ClCCBr>>COc1cc2c(Oc3cc4cccnc4nc3C)ccnc2cc1OCCCl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040167119A1,CC1Cc2c([nH]c3ccc(OCc4ccccc4)cc23)CN1>>CC1Cc2c([nH]c3ccc(O)cc23)CN1,[Pd],CCO,,,,test
US04866077,Cl.Cn1nnc(-c2cccnc2)n1>>Cl.Cn1nnc(C2CCCNC2)n1,,CC(C)=O,CCOCC,,,test
US20090270460A1,CCCCOc1cc(C(=O)O)cc(C(=O)OC)c1>>CCCCOc1cc(CO)cc(CO)c1,,C1CCOC1,,CCCCCC,,test
US20120322791A1,Brc1ccc(Br)nc1.O=C1CCC1>>OC1(c2ccc(Br)cn2)CCC1,,Cc1ccccc1,,[Li]CCCC,,test
US20140080808A1,CSC1=NCCS[C@@](C)(CO[Si](C)(C)C(C)(C)C)C1.Cc1ncc(-c2ccc(C3(C(=O)NN)CC3)cc2)cn1>>Cc1ncc(-c2ccc(C3(c4nnc5n4CCS[C@@](C)(CO[Si](C)(C)C(C)(C)C)C5)CC3)cc2)cn1,,CC(C)(C)O,,,,test
US20120316170A1,CC(=O)c1nc(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(C)n1COCC[Si](C)(C)C>>CC(=O)c1nc(CO)c(C)n1COCC[Si](C)(C)C,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130267493A1,COC(=O)c1c[nH]c2cc(Cl)c(-c3ccc(OCCCN4CCOCC4)cc3)cc12>>O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(OCCCN4CCOCC4)cc3)cc12,,CCOC(C)=O,CO,Cl,[Na+].[OH-],test
US20100029637A1,COC(=O)CCCBr.S=C1N=C2C=CC=CN2C1Cc1cccc2ccccc12>>COC(=O)CCCSC1N=C2C=CC=CN2C1Cc1cccc2ccccc12,,CC(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US05175301,C1CCNCC1.CSC(=C[N+](=O)[O-])SC>>CSC(=C[N+](=O)[O-])N1CCCCC1,,CCO,,,,test
US20040259923A1,CC(=O)Nc1nc(CCc2ccc(CN)cc2)cs1.CC(C)(C)OC(=O)N=C(NC(=O)OC(C)(C)C)n1cccn1>>CC(=O)Nc1nc(CCc2ccc(CNC(NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)cc2)cs1,,C1CCOC1,,,,test
US20030207877A1,BrBr.CC(=O)c1ccc(C#N)s1>>N#Cc1ccc(C(=O)CBr)s1,,C1COCCO1,CCOCC,,,test
US20160176829A1,CCOC(=O)CN(C)C#N.NO>>CCOC(=O)CN(C)C(=N)NO,,CCO,,Cl,,test
US20130130997A1,CO[C@@]1(c2ccc(Cl)c(Cc3ccc(OCC(F)(F)F)cc3)c2)O[C@@](C=O)(CO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>CO[C@@]1(c2ccc(Cl)c(Cc3ccc(OCC(F)(F)F)cc3)c2)OC(CO)(CO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,,O,,[BH4-].[Na+],,test
US20020198194A1,CCOC(=O)CBr.Cc1cc(N2CCCC2)c2ccc(O)cc2n1>>CCOC(=O)COc1ccc2c(N3CCCC3)cc(C)nc2c1,,CN(C)C=O,,[H-].[Na+],,test
US20110288063A1,OC1CC2CCC1CC2>>O=C1CC2CCC1CC2,,CC(Cl)Cl,,,,test
US20060074243A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CS(=O)(=O)c1ccc(Br)cc1>>CC(C)(C)OC(=O)CS(=O)(=O)c1ccc(Br)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20040006067A1,CNC(=O)Nc1ccccc1C1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)OC(C)(C)C)CC1>>CNC(=O)Nc1ccccc1C1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@@H]2Cc3ccccc3CN2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070287712A1,N#CC(C#N)=C(Cl)c1ccccc1.O=C(C(=O)N1CCNCC1)c1c[nH]c2ccccc12>>N#CC(C#N)=C(c1ccccc1)N1CCN(C(=O)C(=O)c2c[nH]c3ccccc23)CC1,,CCO,,CCN(CC)CC,,test
US20120122848A1,O=C(O)C(F)(F)F.O=S(=O)(Cl)Cl.Oc1cc2c(cc1F)C[C@H]1NCC[C@@]23CCCC[C@@H]13>>O=C(O)C(F)(F)F.Oc1c(F)cc2c(c1Cl)[C@@]13CCCC[C@H]1[C@@H](C2)NCC3,,CC(=O)O,,,,test
US20110105462A1,CS(=O)(=O)Cl.Cc1ccc(S(=O)(=O)OCC2COc3ccc(O)cc3O2)cc1>>Cc1ccc(S(=O)(=O)OCC2COc3ccc(OS(C)(=O)=O)cc3O2)cc1,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20090181928A1,O=C1CN(c2ccc(CC(Cc3ccccc3)C(=O)c3ccccc3)cc2OCc2ccccc2)S(=O)(=O)N1>>O=C1CN(c2ccc(CC(Cc3ccccc3)C(=O)c3ccccc3)cc2O)S(=O)(=O)N1,[Pd],CCO,O,,,test
US06458775B1,CC(C)(C)O.CC(C)(C)OC(=O)CCC(C[PH](=O)O)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)CCC(C[PH](=O)OC(C)(C)C)C(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,O,,test
US04544504,CCCC/C=C\CCCCCCCCCC=O.[OH-]>>CCCC/C=C\CCCCCCCCCC(=O)O,,O,,CCO,,test
US20060257987A1,CC1CCOS(=O)(=O)O1.CCOC(=O)C(C)(C)Oc1ccc(O)cc1>>CCOC(=O)C(C)(C)Oc1ccc(OCCC(C)O)cc1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130040995A1,CC(=O)Cl.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(N)c3)c3ccccc23)cc1>>CC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)c3ccccc23)ccn1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20070105943A1,O=C1NC(=O)c2ccccc21.OCc1ccc(COc2ccccc2)cn1>>O=C1c2ccccc2C(=O)N1Cc1ccc(COc2ccccc2)cn1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060135554A1,CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CCC(C)C)cc1.O=[Mn]=O>>CCOc1ccc(C(=O)c2nc3cc(C(=O)N(CC)CC)ccc3n2CCC(C)C)cc1,O=[Mn]=O,ClCCl,,C1COCCO1,,test
US20110009390A1,Cc1cc(C)nc(N2CCN(c3ccc(N)cc3)CC2)c1.O=C(Cl)C(=O)c1c(C2CCCC2)cc2n1CCCC2>>Cc1cc(C)nc(N2CCN(c3ccc(NC(=O)C(=O)c4c(C5CCCC5)cc5n4CCCC5)cc3)CC2)c1,,C1CCOC1,,CCN(CC)CC,,test
US06066704,Cc1ccc(O)c(C(C)(C)C)c1.O=C1CCC(=O)N1Br>>Cc1cc(Br)c(O)c(C(C)(C)C)c1,,CN(C)C=O,,,,test
US20090099155A1,CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(SCc3ccc(Br)c(F)c3)c2CC1.COc1ccc(F)cc1B(O)O>>COc1ccc(F)cc1-c1ccc(CSc2c(Cl)ccc3c2CCN(C(=O)OC(C)(C)C)CC3)cc1F,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,O=C([O-])[O-].[K+].[K+],test
US20100016319A1,BrCc1ccccc1.Cc1ccc([N+](=O)[O-])cc1O>>Cc1ccc(N)cc1OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060052371A1,CC(C)(C)OC(=O)CCc1cccc(C#N)c1.COC(=O)c1ccccc1S>>CC(C)(C)OC(=O)CCc1cccc(-c2nc(=O)c3ccccc3s2)c1,,Cc1ccccc1,,CCN(CC)CC,,test
US20080287394A1,CC(=O)Nc1nn(Cc2ccc(F)cc2)c(=O)c2c(OCc3ccccc3)c3n(c12)CCN(C)C3=O.CI>>CC(=O)N(C)c1nn(Cc2ccc(F)cc2)c(=O)c2c(O)c3n(c12)CCN(C)C3=O,,CN(C)C=O,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20100278835A1,CC1(C(Cl)(Cl)Cl)c2ccccc2NC(=O)N1C1CC1.CCN(CC)CC>>CC1(C)c2ccccc2NC(=O)N1C1CC1.N,[Pd],CO,,,,test
US20150376160A1,CCOC(=O)C1(c2ccc(-c3ccc(-c4sc(F)cc4NC(=O)OC(C)c4ccc(F)cc4C)cc3OC)cc2)CC1>>COc1cc(-c2sc(F)cc2NC(=O)OC(C)c2ccc(F)cc2C)ccc1-c1ccc(C2(C(=O)O)CC2)cc1,,CC(C)O,,Cl,[Na+].[OH-],test
US20110118283A1,CC(C)(C)OC(=O)C(C#N)c1ncc(Br)cn1>>N#CCc1ncc(Br)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030187045A1,N[C@@H]1CCCC[C@H]1NC(=O)Nc1c(Cl)cccc1C(F)(F)F.O=P(Cl)(Cl)Cl>>Cl.FC(F)(F)c1cccc(Cl)c1N=C1N[C@@H]2CCCC[C@H]2N1,,O=P(Cl)(Cl)Cl,,,,test
US04595765,O=[N+]([O-])C=Cc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1.O=[N+]([O-])O>>O=[N+]([O-])/C=C/c1cc(OCc2ccccc2)c(OCc2ccccc2)cc1[N+](=O)[O-],,CC(=O)O,,,,test
US08329682B2,Cc1c(C=O)[nH]c2c1C(=O)N(C[C@@H](O)CN1CCOCC1)CCC2>>Cc1c[nH]c2c1C(=O)N(CC(O)CN1CCOCC1)CCC2,,CCO,,C1CCNCC1,,test
US20090099176A1,COC(=O)CN1C(=O)C(NC(=O)c2cc3cc(Cl)ncc3[nH]2)Cc2ccc(Cl)cc21>>O=C(O)CN1C(=O)C(NC(=O)c2cc3cc(Cl)ncc3[nH]2)Cc2ccc(Cl)cc21,,CO,CS(C)=O,[Na+].[OH-],,test
US20090209586A1,Nc1ccc(C(=O)c2ccccc2)cc1.O=[N+]([O-])c1ccccc1F>>O=C(c1ccccc1)c1ccc(Nc2ccccc2[N+](=O)[O-])cc1,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20100160373A1,CC(=O)O.Fc1ccc([Mg]Br)cc1.O=C(O)c1ccc(Cl)nc1>>O=C1CC(c2ccc(F)cc2)C(C(=O)O)=CN1,,C1CCOC1,,,,test
US20050065118A1,C[Si](C)(C)C=[N+]=[N-].O=C(O)CCc1cccc(O)c1>>COC(=O)CCc1cccc(O)c1,,CC#N,,CC(=O)O,,test
US20140045872A1,COC(OC)c1ccncc1Br.O=C1NCCc2ccc(C(F)(F)F)cc21>>COC(OC)c1ccncc1N1CCc2ccc(C(F)(F)F)cc2C1=O,I[Cu]I,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20090105306A1,C[C@@H]1CCC(CO)O1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCC2CC[C@@H](C)O2)cc1,,ClCCl,,CCN(CC)CC,,test
US20070161645A1,CC(C)(C)OC(=O)N1CCCNCC1.Cc1nc(Cl)cc(Cl)n1>>Cc1nc(Cl)cc(N2CCCN(C(=O)OC(C)(C)C)CC2)n1,,C1COCCO1,,,,test
US20020077329A1,CCc1nc2cc(C(F)(F)F)c(Cl)cc2n1-c1ccc(CCN(C(=O)[O-])S(=O)(=O)c2ccc(C)cc2)cc1.Cc1ccc(S(=O)(=O)O)cc1>>CCc1nc2cc(C(F)(F)F)c(Cl)cc2n1-c1ccc(CCN(C(=O)O)S(=O)(=O)c2ccc(C)cc2)cc1.Cc1ccc(S(=O)(=O)O)cc1,,CC(C)=O,,,,test
US20140350019A1,COc1cc(C(=O)Nc2c(C)ccc(O)c2C)cc(-c2cccc(F)c2)c1>>COc1cc(CNc2c(C)ccc(O)c2C)cc(-c2cccc(F)c2)c1,,C1CCOC1,,,,test
US20150315188A1,C1CCC(C2CO2)CC1.Cc1cc(C)c2[nH]c3c(c2c1)[C@H]1CCCN1CC3>>Cc1cc(C)c2c(c1)c1c(n2C[C@H](O)C2CCCCC2)CCN2CCC[C@H]12,,CN(C)C=O,,[H-].[Na+],,test
US20060287291A1,CCOC(=O)c1coc2c([N+](=O)[O-])cc(Br)cc12>>O=C(O)c1coc2c([N+](=O)[O-])cc(Br)cc12,,CCO,,[Na+].[OH-],,test
US20060030583A1,Brc1cnc2[nH]ccc2c1.O=C(Cl)c1ccccc1>>O=C(c1ccccc1)c1c[nH]c2ncc(Br)cc12,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20040259857A1,O=C(O)c1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1.O=S(Cl)Cl>>O=C(Cl)c1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1,,Cc1ccccc1,,,,test
US20080119488A1,O=[N+]([O-])c1ccc(F)cc1.OB(O)c1ccc(O)cc1>>O=[N+]([O-])c1ccc(Oc2ccc(B(O)O)cc2)cc1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20030207858A1,CC(C)(C)OC(=O)N1CC(Oc2cccnc2)C1>>c1cncc(OC2CNC2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110021514A1,FC(F)(F)c1ccc2c(n1)OCC(COCc1ccccc1)O2>>OCC1COc2nc(C(F)(F)F)ccc2O1,[Pd],CCO,,,,test
US20120316361A1,CCC[C@@H](CN[C@H](C)c1ccccc1)CC(=O)O.CCOC(C)=O.CO>>Oc1ccc2ccccc2c1-c1c(O)ccc2ccccc12,,CO,,Cl,,test
US20140249162A1,CCn1c(C)c(C)c2c(-c3ccccc3)c(C(OC(C)(C)C)C(=O)OC)c(C)nc21.Cc1ccc(B(O)O)cc1>>CCn1c(C)c(C)c2c(-c3ccc(C)cc3)c(C(OC(C)(C)C)C(=O)OC)c(C)nc21,,CC(=O)N(C)C,O,O=C([O-])O.[Na+],,test
US20120115844A1,Clc1ccc(Cl)nn1.Cn1nnc(-c2ccccn2)c1CO>>Cn1nnc(-c2ccccn2)c1COc1ccc(Cl)nn1,,C1CCOC1,,[H-].[Na+],,test
US05521167,CCOC(CBr)OCC.C[C@]12CC[C@H]3[C@@H](CCC4C[C@@H](O)CC[C@@]43C)[C@@H]1CC1OCCOC12>>CCOC(CO[C@H]1CC[C@@]2(C)C(CC[C@H]3[C@@H]4CC5OCCOC5[C@@]4(C)CC[C@@H]32)C1)OCC,,C1CCOC1,,O,[H-].[Na+],test
US20150210682A1,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCCCn3cncn3)cc1CC2C(C)(C)C>>COc1cc2c(cc1OCCCn1cncn1)CC(C(C)(C)C)n1cc(C(=O)O)c(=O)cc1-2,,CCO,O,Cl,[Na+].[OH-],test
US20110230521A1,CCCC=N[S@@](=O)C(C)(C)C.FC(F)(F)c1cccc(Br)n1>>CCC[C@H](N[S@@](=O)C(C)(C)C)c1cccc(C(F)(F)F)n1,,CCOCC,,[Li]CCCC,[Cl-].[NH4+],test
US20140349993A1,C1CCNC1.Nc1cc(Cl)ncn1>>Nc1cc(N2CCCC2)ncn1,,CO,,,,test
US05767268,CC(=O)OC[C@H]1O[C@@](O)(Cc2ccccc2)[C@H](NC(=O)c2ccc3cc(C(=O)N[C@@H]4[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O[C@@]4(O)Cc4ccccc4)ccc3c2)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>O=C(N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@]1(O)Cc1ccccc1)c1ccc2cc(C(=O)N[C@@H]3[C@@H](O)[C@H](O)[C@@H](CO)O[C@@]3(O)Cc3ccccc3)ccc2c1,,C1COCCO1,CO,C[O-].[Na+],,test
US20090105124A1,Nc1ncccc1C(=O)O.O=C(Cl)c1cncc(Cl)c1>>O=C(Nc1ncccc1C(=O)O)c1cncc(Cl)c1,,C1CCOC1,,CN(C)C=O,,test
US20130143871A1,CCOC(=O)c1cnn(-c2nc(Cl)c3cc(Oc4c(C)cccc4C)c(F)cc3n2)c1.N>>CCOC(=O)c1cnn(-c2nc(N)c3cc(Oc4c(C)cccc4C)c(F)cc3n2)c1,,C1CCOC1,,CO,,test
US20030130518A1,CCc1nc2c(N)nc3ccccc3c2n1CCOCCN.O=C(Cl)N1CCOCC1>>CCc1nc2c(N)nc3ccccc3c2n1CCOCCNC(=O)N1CCOCC1,,c1ccncc1,,,,test
US20020177559A1,CCC1CNCCC1N.O=C(O)c1cn(C2CC2)c2nc(F)c(F)cc2c1=O>>CCC1CN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CCC1N,,CC#N,,,,test
US06113527,CCOCC.N#CC1(Nc2cccc(F)c2)CCN(C2Cc3cccc4cccc2c34)CC1.O=C(O)/C=C/C(=O)O>>O=C(O)/C=C/C(=O)O.O=C1CC2(CCN(C3Cc4cccc5cccc3c45)CC2)N1c1cccc(F)c1,,CCOCC,,,,test
US20020193402A1,CC(C)(C)OC(=O)[C@H]1C[C@]2(c3ccccc3)N[C@H]1CC[C@H]2OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1.CO.Cl>>COC(=O)[C@H]1C[C@]2(c3ccccc3)N[C@H]1CC[C@H]2OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1.Cl,,CCOCC,,,,test
US20130197039A1,CCOCC(CN(Cc1ccc(OC)cc1)Cc1ccc(OC)cc1)Oc1ccccn1>>CCOCC(CN)Oc1ccccn1,[Pd],CC(C)(C)O,,,,test
US20160151370A1,CCOc1cc(F)c(Cn2nc(-c3ncc(OCCCSC)c(Nc4ccncc4)n3)c(C)c2C2CC2)c(F)c1.O=C(OO)c1cccc(Cl)c1>>CCOc1cc(F)c(Cn2nc(-c3ncc(OCCCS(C)=O)c(Nc4ccncc4)n3)c(C)c2C2CC2)c(F)c1,,ClC(Cl)Cl,ClCCl,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20140179666A1,CC(C)(C)OC(=O)N1CC(C)(C)c2nnc(Cl)cc21>>CC1(C)CNc2cc(Cl)nnc21,,CCOC(C)=O,,Cl,,test
US20070078184A1,C[C@H](NC(=O)C(F)(F)F)[C@H](O)c1ccc(OCc2ccccc2)c(NS(C)(=O)=O)c1>>C[C@H](N)[C@H](O)c1ccc(OCc2ccccc2)c(NS(C)(=O)=O)c1,,CO,,Cl,[Na+].[OH-],test
US04333934,CCn1c(=O)c2nc(C=O)cn2c2ccccc21.NO>>CCn1c(=O)c2nc(C=NO)cn2c2ccccc21,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20160115119A1,CC(C)(C)[S@@](=O)N[C@@H]1CCc2c(F)cc(Cl)cc21.Cl>>Cl.N[C@@H]1CCc2c(F)cc(Cl)cc21,,C1COCCO1,CO,CC(C)OC(C)C,,test
US20120196845A1,Cc1ccccc1-n1nc2c3c(O)cccc3n(Cc3ccc(-n4cccn4)cc3)cc-2c1=O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1ccccc1-n1nc2c3c(OS(=O)(=O)C(F)(F)F)cccc3n(Cc3ccc(-n4cccn4)cc3)cc-2c1=O,,c1ccncc1,,O=C([O-])O.[Na+],,test
US20130072495A1,COc1ccc(F)c(Cl)c1C(C)C=O.Fc1ccc(Br)cn1>>COc1ccc(F)c(Cl)c1C(C)C(O)c1cc(Br)cnc1F,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20090118284A1,Fc1cc(N2CCNCC2)ccc1-c1ncccn1.O=C(Cl)CCl>>O=C(CCl)N1CCN(c2ccc(-c3ncccn3)c(F)c2)CC1,,C1CCOC1,,CCN(CC)CC,,test
US07172749B2,O=[N+]([O-])c1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OCCCN1CCOCC1>>Nc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OCCCN1CCOCC1,[Ni],,,NN,O,test
US20070078184A1,CCOC(=O)C(F)(F)F.C[C@H](N)[C@H](O)c1ccc(O)cc1>>C[C@H](NC(=O)C(F)(F)F)[C@H](O)c1ccc(O)cc1,,CCO,,,,test
US20090325953A1,O=C(Cl)C(=O)Cl.O=C(O)c1c(F)cc(F)cc1F>>O=C(Cl)c1c(F)cc(F)cc1F,,ClCCl,,CN(C)C=O,,test
US20070060754A1,CCCn1c(COCC)nc2c(N)nc3ccc(OCCNC(=O)OC(C)(C)C)cc3c21>>CCCn1c(COCC)nc2c(N)nc3ccc(OCCN)cc3c21,,CCO,,Cl,,test
US20060128790A1,Cc1c(C)c2c(c(C)c1O)CC1(CCC1)CN2c1ccc(Cl)cc1.O=[N+]([O-])O>>Cc1cc([N+](=O)[O-])c(C)c(C)c1O,,CC(=O)O,,,,test
US20150203511A1,CCOC(=O)CC(=O)c1ccc(OC(C)C)c(C)c1.NN>>Cc1cc(-c2cc(O)[nH]n2)ccc1OC(C)C,,CCO,,,,test
US20140031336A1,CC(=O)N1c2ccc(-c3ccc(CCC(=O)O)cc3)cc2[C@H](Nc2ccc(C#N)cn2)C[C@@H]1C.CN(C)CCN>>CC(=O)N1c2ccc(-c3ccc(CCC(=O)NCCN(C)C)cc3)cc2[C@H](Nc2ccc(C#N)cn2)C[C@@H]1C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070265272A1,CC1(C)CO1.c1cnc2ccc(Cn3nnc4ncc(-c5cn[nH]c5)nc43)cc2c1>>CC(C)(O)Cn1cc(-c2cnc3nnn(Cc4ccc5ncccc5c4)c3n2)cn1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090239845A1,Cc1cc(NC(=O)c2ccccc2COC(=O)c2ccccc2)nn1Cc1cc(Cl)ccc1OCC(C)C>>Cc1cc(NC(=O)c2ccccc2CO)nn1Cc1cc(Cl)ccc1OCC(C)C,,CCO,,C,C[O-].[Na+],test
US20030078415A1,Cc1cn([C@@H]2O[C@H](CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)[C@@H](O)[C@H]2OCCO)c(=O)n(COCc2ccccc2)c1=O>>Cc1cn([C@@H]2O[C@H](CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)[C@@H](O)[C@H]2OCCO)c(=O)[nH]c1=O,[Pd],,,,,test
US20100179128A1,C=CCn1c(Cl)nc2c1c(=O)n(CCCc1cccc(OC)c1)c(=O)n2CCCCC>>CCCCCn1c(=O)n(CCCc2cccc(OC)c2)c(=O)c2[nH]c(Cl)nc21,,C1CCOC1,,,,test
US20160222006A1,C#Cc1ccc(N)cc1.Cc1nc2ncccc2c(=O)o1>>C#Cc1ccc(-n2c(C)nc3ncccc3c2=O)cc1,,CC(=O)O,,,,test
US20100298325A1,Clc1ccc(Oc2cccc(N3CCOCC3)c2)cn1.Nc1cccc(OCc2ccccc2)c1>>c1ccc(COc2cccc(Nc3ccc(Oc4cccc(N5CCOCC5)c4)cn3)c2)cc1,,C1COCCO1,CCOC(C)=O,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20060094764A1,Cc1ccc(C)c(-c2cc(C#N)c(NC(=O)[C@@H]3C[C@@H]4CC[C@H]3C4)s2)c1.O=C1CCC(=O)N1Cl>>Cc1ccc(C)c(-c2sc(NC(=O)[C@@H]3C[C@@H]4CC[C@H]3C4)c(C#N)c2Cl)c1,,CC(=O)O,,O,,test
US05731336,CC(C)(C)c1cc(C=C2NC(=O)CS2)cc(C(C)(C)C)c1O.CSCCCl>>CSCCN1CSC(=Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C1=O,,CCOCC,Cl,CN(C)C=O,[H-].[Na+],test
US20100292253A1,CC(C)(C)OC(=O)Nc1cnc(Br)s1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1cnc(Br)s1,,CCOC(C)=O,O,C1CCOC1,[H-].[Na+],test
US05108485,Cc1nc2c(C(=O)NC(C)(C(N)=O)C(C)C)c(C(=O)O)ccc2n1Cc1ccccc1>>Cc1nc2c(C3=NC(C)(C(C)C)C(=O)N3)c(C(=O)O)ccc2n1Cc1ccccc1,,O,,Cl,[Na+].[OH-],test
US20140018393A1,COC(=O)c1ccc(CN2CCC(C=O)CC2)cc1.N[C@@H]1C[C@H]1c1ccc(C2CC2)cc1>>COC(=O)c1ccc(CN2CCC(CN[C@@H]3C[C@H]3c3ccc(C4CC4)cc3)CC2)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US03987039,CCON=CC1=C(C(=O)O)N2C(=O)C(NC(=O)Cc3cccs3)[C@H]2S(=O)C1>>CCON=CC1=C(C(=O)O)N2C(=O)C(NC(=O)Cc3cccs3)[C@H]2SC1,,CN(C)C=O,,CC(=O)Cl,,test
US20040186127A1,CC(C)(C)OC(=O)n1ccc2cc(CCl)ccc21.OC1CCCCC1>>CC(C)(C)OC(=O)n1ccc2cc(COC3CCCCC3)ccc21,,CCOCC,,,,test
US20160159815A1,CC(C)(C)OC(=O)N1CC[C@](COS(C)(=O)=O)(c2ccccn2)[C@@H](O)C1>>CC(C)(C)OC(=O)N1CC[C@@]2(c3ccccn3)CO[C@H]2C1,,CCOC(C)=O,Cc1ccccc1,C1CCC2=NCCCN2CC1,,test
US20140187553A1,CO.Cc1ccc(S(=O)(=O)n2cc(I)c3nc(C(=O)O)ccc32)cc1>>COC(=O)c1ccc2c(n1)c(I)cn2S(=O)(=O)c1ccc(C)cc1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20050032786A1,CC(C)(C)OC(=O)CCOCCc1cccc(C#N)n1.COC(=O)c1ccccc1S>>CC(C)(C)OC(=O)CCOCCc1cccc(-c2nc(=O)c3ccccc3s2)n1,,Cc1ccccc1,,CCN(CC)CC,,test
US20080255358A1,CN1CCCC1.Cc1nc2c(Br)cc(Br)cn2c1C.c1cn[nH]c1>>Cc1nc2c(N)cc(-n3cccn3)cn2c1C,[Cu]I,CO,,O=C([O-])[O-].[K+].[K+],,test
US04920133,COC(=O)c1cccc(Cc2cccc(OCc3ccc4ccccc4n3)c2)c1>>O=Cc1cccc(Cc2cccc(OCc3ccc4ccccc4n3)c2)c1,,C1CCOC1,CCCCCC,CC(C)C[Al+]CC(C)C.[H-],,test
US20040009995A1,COC(=O)c1cc(C)c(Br)c([N+](=O)[O-])c1>>Cc1cc(C(=O)O)cc([N+](=O)[O-])c1Br,,CCOC(C)=O,CO,Cl,[Na+].[OH-],test
US20120178086A1,COC(=O)c1ccc(CO)cc1.C[Si](C)(C)Cl>>COC(=O)c1ccc(CO[Si](C)(C)C)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20110257242A1,COC1(c2ccc(F)c(F)c2)CCN(C(C)C)C1.O=C(OO)c1cccc(Cl)c1>>COC1(c2ccc(F)c(F)c2)CC[N+]([O-])(C(C)C)C1,,ClCCl,,,,test
US20140249133A1,COC(=O)c1ccc(Cn2nc(-c3ncc(OC)c(Nc4ccncc4)n3)c3ccccc32)c(Cl)c1>>COc1cnc(-c2nn(Cc3ccc(C(=O)O)cc3Cl)c3ccccc23)nc1Nc1ccncc1,,CCOC(C)=O,CO,CC(=O)O,[Na+].[OH-],test
US20150166564A1,CCC#N.CCOC(=O)c1cn(C)cn1>>CC(C#N)C(=O)c1cn(C)cn1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20040241192A1,CN1CCNCC1.O=C1Nc2cc(F)c(F)cc2C1=O>>CN1CCN(c2cc3c(cc2F)C(=O)C(=O)N3)CC1,,CCOC(C)=O,CS(C)=O,,,test
US20120208732A1,C=CCCCCCCCC(=O)O.CCCCCCCC/C=C\CCCCCCCCO>>C=CCCCCCCCC(=O)OCCCCCCCCC=CCCCCCCCC,,CCCCCC,CCOC(C)=O,,,test
US20090209607A1,COC(=O)c1cc(-c2ccnn2C)cs1.O=C1CCC(=O)N1I>>COC(=O)c1cc(-c2c(I)cnn2C)cs1,,C1CCOC1,,,,test
US20070105900A1,C1COCCN1.COc1ccc(Cn2cc(NC(=O)c3c(F)cccc3F)c(-c3nc(C=O)c(-c4ccc(F)cc4)[nH]3)n2)cc1>>COc1ccc(Cn2cc(NC(=O)c3c(F)cccc3F)c(-c3nc(CN4CCOCC4)c(-c4ccc(F)cc4)[nH]3)n2)cc1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20120022057A1,C=C(C)CO.O=[N+]([O-])c1ccc(Br)cc1F>>C=C(C)COc1cc(Br)ccc1[N+](=O)[O-],,C1CCOC1,ClCCl,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20040058894A1,O=C(OCc1ccccc1)N1CCC(c2nnn[nH]2)C1>>C1CC(c2nnn[nH]2)CN1,[Pd],CO,,[H][H],,test
US20130210844A1,COc1c(CNC(=O)C(C)(C)C)ccc(Cl)c1C(=O)O.Nc1cccc2c(Oc3cccc(C(F)(F)F)c3)ncnc12>>COc1c(CNC(=O)C(C)(C)C)ccc(Cl)c1C(=O)Nc1cccc2c(Oc3cccc(C(F)(F)F)c3)ncnc12,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20150367027A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCCOCCOCCCl>>Cc1ccc(S(=O)(=O)OCCOCCOCCCl)cc1,,ClCCl,,CCN(CC)CC,,test
US20100048568A1,NCl.c1cc2cc[nH]c2cn1>>Nn1ccc2ccncc21,,CCOCC,CN(C)C=O,CC(C)(C)[O-].[K+],,test
US20070238700A1,Nc1ccc(Cl)cc1C1=NN(c2ccccc2)CC1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=S(=O)(Nc1ccc(Cl)cc1C1=NN(c2ccccc2)CC1)C(F)(F)F,,ClCCl,,,,test
US06410739B1,CCOC(=O)C=C[C@H]1CCCN1C(=O)OCc1ccccc1>>O=C(OCc1ccccc1)N1CCC[C@@H]1C=CCO,,O=C([O-])O,[Na+],CC(C)C[Al+]CC(C)C.[H-],,test
US20030181728A1,O=C(Nc1ccc([N+](=O)[O-])c(C(F)(F)F)c1)C12OC1C1CCC2CC1.O=P(NO)(c1ccccc1)c1ccccc1>>NN(C(=O)C12OC1C1CCC2CC1)c1ccc([N+](=O)[O-])c(C(F)(F)F)c1,,CN(C)C=O,,[H-].[Na+],,test
US04567178,CN1CCC(N)CC1.O=C1Nc2ccccc2C(C(=O)O)c2ccccc21>>CN1CCC(NC(=O)C2c3ccccc3NC(=O)c3ccccc32)CC1,,C1CCOC1,,,,test
US20100311966A1,CCOC(=O)c1sc(N2CC[C@H](NC(=O)c3nc(Cl)c(CC)[nH]3)[C@H](OCC(F)F)C2)nc1C>>CCc1[nH]c(C(=O)N[C@H]2CCN(c3nc(C)c(C(=O)O)s3)C[C@H]2OCC(F)F)nc1Cl,,C1CCOC1,,CO,[Li+].[OH-],test
US05686458,CCOC(=O)COc1cccc2c(N3CCc4ccccc4C3C)nc(Nc3ccc(F)cc3C)nc12>>Cc1cc(F)ccc1Nc1nc(N2CCc3ccccc3C2C)c2cccc(OCCO)c2n1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20070135477A1,C1COCCN1.CCOc1cc2[nH]c(-c3n[nH]cc3NC(=O)c3c(F)cccc3F)nc2cc1C(=O)O>>CCOc1cc2[nH]c(-c3n[nH]cc3NC(=O)c3c(F)cccc3F)nc2cc1C(=O)N1CCOCC1,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20050234265A1,CC(C)(C)c1cc(O)c(-c2ccc(Cl)cc2)c(C(C)(C)C)c1.O=C(CCl)NCO>>CC(C)(C)c1cc(C(C)(C)C)c(-c2ccc(Cl)cc2)c(O)c1CNC(=O)CCl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130116216A1,O=C=NCc1ccccc1.O=[N+]([O-])c1ccc(S(=O)(=O)N2CCNCC2)cc1>>O=C(NCc1ccccc1)N1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CC1,,c1ccncc1,,,,test
US05688798,CC(C)(C)OC(=O)N1CCc2cc(-c3cc(Cl)cc(Cl)c3)ccc2C1.Cl>>Cl.Clc1cc(Cl)cc(-c2ccc3c(c2)CCNC3)c1,,CCOC(C)=O,,,,test
US20120214762A1,CC(C)(O)c1n[nH]c2cc(Br)ccc12.Nc1nccc(Cl)n1>>CC(C)(O)c1nn(-c2ccnc(N)n2)c2cc(Br)ccc12,,CN(C)C=O,,[H-].[Na+],,test
US20120208819A1,C[C@H](NC(=O)c1nc(Br)cnc1N)c1ccc(F)c(F)c1.N#C[Cu]>>C[C@H](NC(=O)c1nc(C#N)cnc1N)c1ccc(F)c(F)c1,,CC(=O)N(C)C,CCOC(C)=O,,,test
US20050009764A1,CCO.NCCCCc1nc(-c2ccc(Cl)nc2)c[nH]1>>CCOc1ccc(-c2c[nH]c(CCCCN)n2)cn1,,CCO,,C,C[O-].[Na+],test
US20120295947A1,CCOC(=O)C=C1CCc2c1[nH]c1ccc(OCc3ccccc3)cc21>>CCOC(=O)CC1CCc2c1[nH]c1ccc(O)cc21,[Pd],CCOC(C)=O,,,,test
US20160272645A1,C=CC(=O)Cl.Nc1ncnc2c1c(-c1cc(O)cc(F)c1)nn2CCNc1ccccc1>>C=CC(=O)N(CCn1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc21)c1ccccc1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US04971984,C=O.CCOC(=O)C1=C(C)NC(CS)=C(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1>>CCOC(=O)C1=C(C)NC(CSCO)=C(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1,,CO,,,,test
US04590272,CSC(=C[N+](=O)[O-])SC.NCCCNCc1ccc(Cl)cc1>>O=[N+]([O-])C=C1NCCCN1Cc1ccc(Cl)cc1,,CCO,,,,test
US20030096826A1,CC(C)(C)OC(=O)CC(NC(=O)OCc1ccccc1)C(N)=O>>CC(C)(C)OC(=O)C[C@H](N)C(N)=O,[Pd],C1CCOC1,,,,test
US20090163552A1,CC(C)(C)OC(=O)COc1ccc(NC(=O)C(C2CCCCC2)n2c(-c3ccc(Cl)cc3)nc3cc(F)c(F)cc32)c(F)c1>>O=C(O)COc1ccc(NC(=O)C(C2CCCCC2)n2c(-c3ccc(Cl)cc3)nc3cc(F)c(F)cc32)c(F)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040019020A1,CCCCCCCCCCP(=O)(OCC)OCC.O=C(Cl)C(=O)Cl>>CCCCCCCCCCP(=O)(Cl)OCC,,CCOCC,,,,test
US07115611B2,CCOC(=O)COc1ccc(N(C)Cc2ccc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1CCCOC>>COCCCc1cc(N(C)Cc2ccc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O,,C1CCOC1,CCO,[Na+].[OH-],,test
US20060003991A1,COc1cccc2c1CCCCN2C(=O)CN1C(=O)[C@@H](Cc2n[nH]c3ccccc23)C(=O)N(c2ccccc2)c2ccccc21>>COc1cccc2c1CCCCN2C(=O)CN1C(=O)[C@@H](Cc2n[nH]c3c2CCCC3)C(=O)N(c2ccccc2)c2ccccc21,[Pd],CCOC(C)=O,,,,test
US20100240678A1,CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(OS(=O)(=O)C(F)(F)F)cc(C(C)=O)c2)c1CCC(=O)OCC.OB(O)c1ccc2c(c1)OC(F)(F)O2>>CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(C(C)=O)cc(-c3ccc4c(c3)OC(F)(F)O4)c2)c1CCC(=O)OCC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US20090325985A1,COc1cnc(Cl)c2[nH]ccc12.N#Cc1nc[nH]n1>>COc1cnc(-n2cnc(C#N)n2)c2[nH]ccc12,[Cu]I,CCOC(C)=O,c1ccncc1,,,test
US20080039452A1,O=C(N[C@@H]1CCCC[C@@H]1C(=O)N1CC[C@@H]2[C@H](c3cccn3C(=O)OCc3ccccc3)Nc3ccccc3[C@@H]21)c1ccccc1>>O=C(N[C@@H]1CCCC[C@@H]1C(=O)N1CC[C@H]2[C@@H](c3ccc[nH]3)Nc3ccccc3[C@H]21)c1ccccc1,[Pd],CO,,,,test
US20060069117A1,NC1CCCCC1.O=[N+]([O-])c1cccnc1Cl>>O=[N+]([O-])c1cccnc1NC1CCCCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05658491,CCCCCCCCc1cnc(-c2ccc(OCCCOCC(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)OC(F)(F)F)cc2)nc1.CCCCCOc1cnc(-c2ccc(O)cc2)nc1>>CCCCCOc1cnc(-c2ccc(OCCCOCC(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)OC(F)(F)F)cc2)nc1,,CN(C)C=O,,,,test
US20120289522A1,Cc1noc(-c2ccc(Br)cc2)c1C1CO1.OCc1ccccc1>>Cc1noc(-c2ccc(Br)cc2)c1C(O)COCc1ccccc1,,CCO,,,,test
US20110059943A1,CC(Br)C=O.CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(N)nc21.O=C(N=C=S)c1ccccc1>>CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(Nc3ncc(C)s3)nc21,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090023758A1,C=C[C@@H]1C[C@]1(NC(=O)C1CC(O)C=C1C(=O)OC)C(=O)OC(C)(C)C.COc1ccc2c(O)cc(-c3ccccc3)nc2c1>>C=C[C@@H]1C[C@]1(NC(=O)C1CC(Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)C=C1C(=O)OC)C(=O)OC(C)(C)C,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120046267A1,Nc1ncc(-c2cnn(CCOC3CCCCO3)c2)c2cc(-c3cccc4cnccc34)oc12>>Nc1ncc(-c2cnn(CCO)c2)c2cc(-c3cccc4cnccc34)oc12,,CO,,Cl,,test
US20150353553A1,COC(=O)c1nc(N[C@H](CCCO)C2CCC2)c2c(n1)nc(-c1cccc(C)c1)n2Cc1ccc(Cl)cc1>>Cc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](CCCO)C4CCC4)c3n2Cc2ccc(Cl)cc2)c1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20130137680A1,CC(C)(N)CCO.O=C(OCc1ccccc1)c1ccc([N+](=O)[O-])c(F)c1>>CC(C)(CCO)Nc1cc(C(=O)OCc2ccccc2)ccc1[N+](=O)[O-],,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04150136,CC(C)Br.c1ccc(C2=C3CCNCC3Cc3ccccc32)cc1>>CC(C)N1CCC2=C(c3ccccc3)c3ccccc3CC2C1,,CN(C)C=O,,[I-].[Na+],,test
US20110009421A1,COc1cccc(CCOc2cccc(-c3cccc(C(=O)NCCNC(=O)OC(C)(C)C)c3)n2)c1.Cl>>COc1cccc(CCOc2cccc(-c3cccc(C(=O)NCCN)c3)n2)c1.Cl,,CCOC(C)=O,,,,test
US20070185329A1,CCOC(=O)O[C@H]1CN2CCC1CC2.c1ccc([C@@H]2NCCc3ccccc32)cc1>>O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1,,CN(C)C=O,Cc1ccccc1,C,C[O-].[Na+],test
US20080045509A1,O=Cc1cc(Br)ccc1F.OCCO>>Fc1ccc(Br)cc1C1OCCO1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100055608A1,CCC(Cl)C(=O)Cl.O=S(=O)([O-])C(F)(F)C(O)C(F)(F)F.c1ccc([S+](c2ccccc2)c2ccccc2)cc1>>O=C(CCCCl)OC(C(F)(F)F)C(F)(F)S(=O)(=O)[O-].c1ccc([S+](c2ccccc2)c2ccccc2)cc1,,CC#N,,Cl,c1ccncc1,test
US20160194340A1,CC(C)(C)OC(=O)[C@@H]1COC(c2cccc3ccccc23)=N1.CC=CCBr>>CC=CC[C@]1(C(=O)OC(C)(C)C)COC(c2cccc3ccccc23)=N1,,ClCCl,,,,test
US20070249649A1,CNS(=O)(=O)CCc1ccc([N+](=O)[O-])cc1>>CNS(=O)(=O)CCc1ccc(N)cc1,[Pd],CO,,,,test
US20090143375A1,CC1(C)C(=O)Nc2cc(N)c(N)cc21.COCCBr>>COCCN1C(=O)C(C)(C)c2cc(N)c(N)cc21,,CN(C)C=O,,O,[H-].[Na+],test
US20020111358A1,CCc1ccc(Br)s1.COc1cccc2oc([Sn](C)(C)C)cc12>>CCc1ccc(-c2cc3c(OC)cccc3o2)s1,,C1CCOC1,,CCOC(C)=O,,test
US20090247567A1,CC(C)(C)Nc1cc2c(cn1)-c1sccc1CCO2.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N(c1cc2c(cn1)-c1sccc1CCO2)C(C)(C)C,,CC(C)(C)O,,,,test
US05350872,CC1(C)OC(=O)CC(=O)O1.O=Cc1ccc([N+](=O)[O-])cc1>>O=C(O)CCc1ccc([N+](=O)[O-])cc1,,CCN(CC)CC,,O=CO,,test
US20100286116A1,O=S(Cl)Cl.OCc1conc1-c1ccccn1>>ClCc1conc1-c1ccccn1,,ClCCl,,,,test
US20150175584A1,COc1ccc2c(Cl)ncnc2c1OC.NC1CCOC1>>COc1ccc2c(NC3CCOC3)ncnc2c1OC,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20090099227A1,CC(C)(C)OC(=O)N1CCC(OCc2noc(-c3cc4c(CO)nccc4o3)n2)CC1.CNC>>CN(C)Cc1nccc2oc(-c3nc(COC4CCN(C(=O)OC(C)(C)C)CC4)no3)cc12,,C1CCOC1,,CCN(CC)CC,CS(=O)(=O)Cl,test
US05559106,NN.O=c1c(Cl)nc2ccc(C(F)(F)F)cc2n1OCc1ccccc1>>NNc1nc2ccc(C(F)(F)F)cc2n(OCc2ccccc2)c1=O,,ClCCl,,O,,test
US05883098,O=C(CBr)OCc1ccccc1.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCNC[C@H]1Cc1c[nH]c2ccccc12>>O=C(CN1CCN(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](Cc2c[nH]c3ccccc23)C1)OCc1ccccc1,,C1CCOC1,,CCN(CC)CC,,test
US05677305,CN(C)S(=O)(=O)c1cc([N+](=O)[O-])c(N)cc1Cl.Oc1ccncc1>>CN(C)S(=O)(=O)c1cc([N+](=O)[O-])c(N)cc1-n1ccc(=O)cc1,,CS(C)=O,,[K+].[OH-],,test
US20040010009A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc([N+](=O)[O-])cc2Br)CC1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(N)cc2Br)CC1,[Zn],CC(=O)O,,,,test
US04751240,COc1cccc(CCC(C(=O)O)c2ccc(F)cc2)c1>>COc1ccc2c(c1)CCC(c1ccc(F)cc1)C2=O,,Cc1ccccc1,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20040152750A1,COC(=O)c1ccc(NCc2ccc(C3=CCCCC3)cc2)cc1.O=C(Cl)C=Cc1cccc(OC(F)(F)F)c1>>COC(=O)c1ccc(N(Cc2ccc(C3=CCCCC3)cc2)C(=O)C=Cc2cccc(OC(F)(F)F)c2)cc1,,Cc1ccccc1,ClCCl,CCN(CC)CC,O=S(Cl)Cl,test
US20060161001A1,CCOC(=O)CC(=O)c1ccccc1.Nc1ncccc1C=O>>CCOC(=O)c1cc2cccnc2nc1-c1ccccc1,,CCOC(C)=O,,C1CCNCC1,,test
US20070208056A1,CC(C)[C@@H](N)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1.O=C(Cl)Oc1ccccc1>>CC(C)[C@@H](NC(=O)Oc1ccccc1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1,,CCOC(C)=O,,CCN(CC)CC,ClCCl,test
US06809199B2,COc1cc(-c2ccc(F)cc2F)c2c(c1)N(c1c(Cl)cccc1Cl)C(=O)CC2.Cl.ClCCl>>COc1cc(-c2ccccc2Cl)c2c(c1)N(c1c(Cl)cccc1Cl)C(=O)CC2.Cl,,C1COCCO1,ClCCl,,,test
US05252107,C=C(C)[C@H]1CC=C(C)CC1.CCCCO>>C.C=C(C)[C@H]1CC=C(C)CC1,,O,,,,test
US20070197558A1,Nc1ccc(S)cc1.O=[N+]([O-])c1cc(OCc2cnc(Cl)s2)ccc1Cl>>Nc1ccc(Sc2ccc(OCc3cnc(Cl)s3)cc2[N+](=O)[O-])cc1,,CCO,,,,test
US05153180,CC(=O)OC(C)=O.Cc1cn([C@H]2C[C@H](F)[C@@H](CO)O2)c(=O)[nH]c1=O>>CC(=O)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@@H]1F,,c1ccncc1,,,,test
US05306728,OCCOc1cccc(-c2ccsc2)c1>>O=CCOc1cccc(-c2ccsc2)c1,,CS(C)=O,,O=C(Cl)C(=O)Cl,,test
US20040220238A1,CC(N)=NO.CON=C1C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1>>CON=C1C[C@@H](c2nc(C)no2)N(C(=O)OC(C)(C)C)C1,,C1CCOC1,ClCCl,CC(C)N=C=NC(C)C,,test
US20150368269A1,CC(=O)O[C@@H](C(=O)Nc1ccc2c(N)nccc2c1C(N)=O)[C@H]1OCCN(c2ccn(-c3ccncc3)n2)C1=O>>Nc1nccc2c1ccc1[nH]c([C@H](O)[C@H]3OCCN(c4ccn(-c5ccncc5)n4)C3=O)nc(=O)c12,,CCO,,[Na+].[OH-],,test
US20050245529A1,O=C1C=C(c2ccc(Br)cc2)CCC1>>OC1CCCC(c2ccc(Br)cc2)C1,,C1CCOC1,,CCOC(C)=O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20020099048A1,CCCCCC.CCO.CCOC(C)=O.NO>>CCOC(=O)CCC1CCCC1=NO,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20110257100A1,BrP(Br)Br.OCCc1ccc(Br)nc1>>BrCCc1ccc(Br)nc1,,ClCCl,,,,test
US04279913,Br.CC(=CN(C)C)C=C(C#N)C(=O)[O-].CC(=O)O>>CCOC(=O)c1cc(C)cnc1Br,,CC(=O)O,,O=C([O-])[O-].[Na+].[Na+],,test
US20140228386A1,FC(F)(F)c1csc2cc(Br)ccc12.O=C1NCCN1c1cnccc1C1CC1>>O=C1N(c2ccc3c(C(F)(F)F)csc3c2)CCN1c1cnccc1C1CC1,I[Cu]I,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20130338152A1,C1CSCCN1.Nc1ncnc2c1c(I)cn2C1CC(=O)C1>>Nc1ncnc2c1c(I)cn2C1CC(N2CCSCC2)C1,,ClCCCl,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20070254879A1,CC(C)(C)OC(=O)NC/C=C/B1OC(C)(C)C(C)(C)O1.O=c1[nH]nc2c3cc4ccccc4cc3c(Br)cn12>>CC(C)(C)OC(=O)NC/C=C/c1cn2c(=O)[nH]nc2c2cc3ccccc3cc12,,C1CCOC1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040030137A1,Cc1csc2c(C3CCN(C(=O)OC(C)(C)C)CC3)noc12.Cl>>Cc1csc2c(C3CCNCC3)noc12.Cl,,CO,,,,test
US20110009454A1,COCc1ccc(C(=O)O)c(N)n1.Cc1ccccc1Oc1cccc(CN)c1>>COCc1ccc(C(=O)NCc2cccc(Oc3ccccc3C)c2)c(N)n1,,CN(C)C=O,O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20050137193A1,CC(C)(c1ccc(S(=O)(=O)Cl)cc1)c1cocn1.Cc1ccc(C(=O)c2cc(Cl)ccc2N)cn1>>Cc1ccc(C(=O)c2cc(Cl)ccc2NS(=O)(=O)c2ccc(C(C)(C)c3cocn3)cc2)cn1,,c1ccncc1,,,,test
US20110112067A1,CC(=O)OCC(=O)Cl.Nc1ccc(Br)cc1F>>CC(=O)OCC(=O)Nc1ccc(Br)cc1F,,ClC(Cl)Cl,,O,,test
US20160031903A1,CC(C)(C)OC(=O)N1CC(C=O)C1.C[Si](C)(C)C(F)(F)F>>CC(C)(C)OC(=O)N1CC(C(O)C(F)(F)F)C1,,C1CCOC1,CCOCC,Cl,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20110257241A1,COC1(c2cc(F)cc(Cl)c2)CCN(C(=O)OC(C)(C)C)C1>>COC1(c2cc(F)cc(Cl)c2)CCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06413995B1,CCOC(=O)Cl.CN(C)C=O.O=C(C=C(c1ccccc1)c1ccc(O)cc1)NCc1cccnc1>>CCOC(=O)COc1ccc(C(=CC(=O)NCc2cccnc2)c2ccccc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040102515A1,C=CCc1c(OCc2ccccc2)cc(O)c2c(=O)c3cccc(OCc4ccccc4)c3oc12.CI>>C=CCc1c(OCc2ccccc2)cc(OC)c2c(=O)c3cccc(OCc4ccccc4)c3oc12,,CN(C)C=O,,CO,[H-].[Na+],test
US04479942,COc1ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc2ccc(OC)cc2)C(=O)N[C@@H]2[C@@H](C(=O)O)O[C@@H](n3cnc4c(N)ncnc43)[C@@H]2O)cc1>>COc1ccc(C[C@H](N)C(=O)N[C@@H](Cc2ccc(OC)cc2)C(=O)N[C@@H]2[C@@H](C(=O)O)O[C@@H](n3cnc4c(N)ncnc43)[C@@H]2O)cc1,,O=CO,,,,test
US20030055085A1,Fc1cc(F)cc(Br)c1.O=C([O-])[O-].c1c[nH]cn1>>O=C(O)c1cc(F)cc(-n2ccnc2)c1,,CN(C)C=O,,O,,test
US20140357641A1,Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)N(CCCCC2CC(OCc4ccccc4)=NO2)CCC3)cc1>>Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)N(CCCCC2CC(=O)NO2)CCC3)cc1,[Pd],CCO,,[H][H],,test
US20060089359A1,CC(Br)CO.O=c1[nH]nc(Br)c2ccc([N+](=O)[O-])cc12>>CC(C)n1nc(Br)c2ccc([N+](=O)[O-])cc2c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20080194547A1,CC(C)(C)OC(=O)NC12CCN(Cc3ccccc3)CC1C2>>CC(C)(C)OC(=O)NC12CCNCC1C2,[Pd],CCO,,,,test
US05466687,COC(=O)c1ccc(C=C2CCN(C(=O)c3ccc(Cl)cc3)CC2)c(F)c1>>O=C(O)c1ccc(C=C2CCN(C(=O)c3ccc(Cl)cc3)CC2)c(F)c1,,CO,O,[K+].[OH-],,test
US04642308,Nc1ccc2ccc(Cl)nc2n1.O=C(O)C1CCC1>>O=C(Nc1ccc2ccc(Cl)nc2n1)C1CCC1,,CC#N,,,,test
US20050107388A1,CC(=O)O.Fc1cccc(Br)c1.O>>O=Cc1c(F)cccc1Br,,C1CCOC1,O,CC(C)NC(C)C,[Li]CCCC,test
US20060154960A1,CC(=O)Cl.CCc1nn(C2CCCC2)c2cc(-c3ccnn3C3CCNCC3)ccc12>>CCc1nn(C2CCCC2)c2cc(-c3ccnn3C3CCN(C(C)=O)CC3)ccc12,,ClCCl,,CCN(CC)CC,,test
US04271163,CC1(C(=O)Cl)CC1.Nc1ccc(C2=NNC(=O)C3CC23)cc1>>CC1(C(=O)Nc2ccc(C3=NNC(=O)C4CC34)cc2)CC1,,C1CCOC1,,,,test
US20040053960A1,COc1cc2c(cc1OC)CNCC2.O=C(CCCCCCCBr)NOCc1ccccc1>>COc1cc2c(cc1OC)CN(CCCCCCCC(=O)NOCc1ccccc1)CC2,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20060172989A1,CCCNCC.O=C1C(=Nc2cccc(C(F)(F)F)c2)c2cc(F)ccc2N1c1cccc(OCCCBr)c1>>CCCN(CC)CCCOc1cccc(N2C(=O)C(=Nc3cccc(C(F)(F)F)c3)c3cc(F)ccc32)c1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US06297196B1,COC(=O)c1cc(C)c2c(c1C)C(=O)CCS2>>COC(=O)c1cc(C)c2c(c1C)C(O)CCS2,,CCO,,[BH4-].[Na+],,test
US20060035956A1,CCOC(=O)Cn1ccc2ccc(OCCCC#Cc3ccc(OC(F)(F)F)cc3)cc21>>O=C(O)Cn1ccc2ccc(OCCCC#Cc3ccc(OC(F)(F)F)cc3)cc21,,C1CCOC1,CO,[Li+].[OH-],,test
US05661161,CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)C.Cl>>CSCC[C@H](N)C(=O)OC(C)C.Cl,,CCOC(C)=O,,,,test
US20160122344A1,COCCCOc1cc(CC(NC=O)C(C)(C)O)ccc1OC>>COCCCOc1cc2c(cc1OC)C=NC(C(C)(C)O)C2,,CC#N,,O=P(Cl)(Cl)Cl,,test
USH0000078,CC(=O)OCCC(CN(CC(CCOC(C)=O)([N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-])([N+](=O)[O-])[N+](=O)[O-]>>O=[N+]([O-])N(CC(CCO)([N+](=O)[O-])[N+](=O)[O-])CC(CCO)([N+](=O)[O-])[N+](=O)[O-],,O,,CO,Cl,test
US20100063119A1,CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1OCCCC(C)OC(C)=O>>CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1OCCCC(C)O,,CO,,[Li+].[OH-],,test
US20070225324A1,CC(=O)OC[C@@H](C)n1ccc2c(NC(=O)Cc3ccc(F)c(C(F)(F)F)c3)c(Cl)ccc2c1=O>>C[C@H](CO)n1ccc2c(NC(=O)Cc3ccc(F)c(C(F)(F)F)c3)c(Cl)ccc2c1=O,O,,,CO,O=C([O-])[O-].[K+].[K+],test
US03948904,CC(=O)OCC1=C(C(=O)O)N2C(=O)C(N)C2SC1.COc1ccc(C(O)C(=O)Cl)c(CCl)c1>>COc1ccc(C(O)C(=O)NC2C(=O)N3C(C(=O)O)=C(COC(C)=O)CSC23)c(CCl)c1,,CCOC(C)=O,,,,test
US20110009261A1,C1CSCN1.N#Cc1c(OC(F)F)cccc1S(=O)(=O)Cl>>N#Cc1c(OC(F)F)cccc1S(=O)(=O)N1CCSC1,,C1CCOC1,,,,test
US20140228323A1,CC(OC(=O)C[C@@H](Cc1ccc(-c2cc(Cl)ccc2F)cc1)NC(=O)OC(C)(C)C)OC(=O)OC1CCCCC1>>CC(OC(=O)C[C@H](N)Cc1ccc(-c2cc(Cl)ccc2F)cc1)OC(=O)OC1CCCCC1,,C1COCCO1,,Cl,,test
US20020042414A1,CCOC(=O)C#CC1=Cc2cc(OC)c(OC)cc2CC1>>COc1cc2c(cc1OC)CCC(C#CC(=O)O)=C2,,C1CCOC1,CO,Cl,[K+].[OH-],test
US20120114696A1,BrCCCCCCCBr.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1CCCCCCCBr,,CC(C)=O,,[K],,test
US20140213586A1,CC(C)(C)OCCn1cc(C(=O)C(Cl)c2ccccc2)c2ccc(F)cc21.COc1cccc(N)c1>>COc1cccc(NC(C(=O)c2cn(CCOC(C)(C)C)c3cc(F)ccc23)c2ccccc2)c1,,CC#N,,,,test
US20100249075A1,BrBr.COc1ccc(C2Cc3ccc(OC)cc3C3CCCCC23)cc1>>COc1ccc(C2Cc3cc(Br)c(OC)cc3C3CCCCC23)cc1,,ClCCl,,,,test
US20080306068A1,Cn1nc(C(C)(C)C)cc1NC(=O)Nc1ccc(OC2CCNCC2)cc1.O=C(O)c1ccccc1>>Cn1nc(C(C)(C)C)cc1NC(=O)Nc1ccc(OC2CCN(C(=O)c3ccccc3)CC2)cc1,,C1CCOC1,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20090131461A1,COc1cc2c(Nc3cc(C)[nH]n3)nc(Cl)nc2cc1OCc1ccccc1.Sc1ccccc1>>COc1cc2c(Nc3cc(C)[nH]n3)nc(Sc3ccccc3)nc2cc1OCc1ccccc1,,CC(C)(C)O,,,,test
US20060100229A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cn1nc(C#N)c(Br)c1CCN>>Cn1nc(C#N)c(Br)c1CCNC(=O)OC(C)(C)C,,CN1CCCC1=O,,O,,test
US20070135385A1,CC(=O)OCCBr.Cc1cc2c(O)ccnc2n1Cc1ccccc1>>CCOC(=O)COc1ccnc2c1cc(C)n2Cc1ccccc1,,CC(C)=O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20130252934A1,CC(C)(C)[Si](C)(C)OC[C@H](c1ccc(Cl)c(F)c1)n1ccc(-c2ccnc(NC3CC4CC3CO4)n2)cc1=O>>O=c1cc(-c2ccnc(NC3CC4CC3CO4)n2)ccn1[C@H](CO)c1ccc(Cl)c(F)c1,,CO,Cl,O=C([O-])[O-].[Na+].[Na+],,test
US05426206,CCC[C@@H](O[Si](CC)(CC)CC)[C@@H](C)CO>>CCC[C@@H](O)[C@H](C)CO,,CCOCC,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20050228014A1,CS(N)(=O)=O.ClC[C@@H]1CO1>>CS(=O)(=O)NC[C@H]1CO1,,O,,Cl,[Na+].[OH-],test
US20020115700A1,O=C(Cl)c1ccc(Cl)c(Cl)c1.O=C1NC(=O)C(=Cc2c[nH]c3ccc(OCc4ccccc4)cc23)S1>>O=C1NC(=O)C(=Cc2cn(C(=O)c3ccc(Cl)c(Cl)c3)c3ccc(OCc4ccccc4)cc23)S1,,c1ccncc1,,CN(C)c1ccccn1,,test
US05739336,CC(C)(C)OC(=O)N1CCC2(CC1)NC(=O)NC2=O.OCC(O)CBr>>CC(C)(C)OC(=O)N1CCC2(CC1)NC(=O)N(CC(O)CO)C2=O,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US06288096B1,COC(=O)Nc1ccc(CCOc2ccc(C=C3SC(=O)NC3=O)cc2)cc1>>COC(=O)Nc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)cc1,[Pd],CCOC(C)=O,,,,test
US20120101083A1,CC(C)(C)OC(=O)CBr.CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCNC4)no2)cc1C#N>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCN(CC(=O)OC(C)(C)C)C4)no2)cc1C#N,,CC#N,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20120088748A1,CC(C)(C)OC(=O)N1CCOC(c2ccc(Cl)c(Cl)c2)C(CN=[N+]=[N-])C1>>CC(C)(C)OC(=O)N1CCOC(c2ccc(Cl)c(Cl)c2)C(CN)C1,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150274696A1,O=[N+]([O-])c1ccc2nscc2c1>>Nc1ccc2nscc2c1,[Fe],CCO,O,Cl,,test
US20140296246A1,CCOc1nc2c(C(O)c3ccc(F)cn3)cc(-c3c(C)noc3C)cc2n1C(=O)OC(C)(C)C>>Cc1noc(C)c1-c1cc(C(O)c2ccc(F)cn2)c2[nH]c(=O)[nH]c2c1,,CCO,,Cl,,test
US20100135999A1,COC(=O)c1cc(OCC(=O)N2CC[C@@H](O)C2)c2ccc(C)cc2n1>>Cc1ccc2c(OCC(=O)N3CC[C@@H](O)C3)cc(C(=O)O)nc2c1,,C1CCOC1,,[Na+].[OH-],,test
US20080064689A1,Brc1ccc(C2=NO[C@H](CN3CCOCC3)C2)nc1.CC1(C)OB(c2ccc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)OC1(C)C>>O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(-c2ccc(C3=NO[C@H](CN4CCOCC4)C3)nc2)c(F)c1,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOCC,CO,O,O=C([O-])[O-].[K+].[K+],test
US06017917,COC(=O)c1cc(C(=O)OC)cc(-c2cc(OC)ccc2Cl)c1>>COC(=O)c1cc(C(=O)O)cc(-c2cc(OC)ccc2Cl)c1,,C1COCCO1,CO,[K+].[OH-],,test
US04325955,Br.OC1(C(c2ccc(F)cc2)c2ccccc2F)CSC2=NCCCN21>>Br.Fc1ccc(C(C2=CSC3=NCCCN23)c2ccccc2F)cc1,,CC(C)=O,,,,test
US20130029980A1,BrCCc1ccccc1.Cc1cc(N)c([N+](=O)[O-])cc1C>>Cc1cc(NCCc2ccccc2)c([N+](=O)[O-])cc1C,,CCOC(C)=O,CCOCC,CCN(C(C)C)C(C)C,,test
US20060235030A1,CN.Cc1ccc(NC(=O)c2ccsc2)cc1-c1nc(S(C)=O)nc2c1CNC(=O)N2c1c(F)cccc1F>>CNc1nc(-c2cc(NC(=O)c3ccsc3)ccc2C)c2c(n1)N(c1c(F)cccc1F)C(=O)NC2,,C1CCOC1,,,,test
US20110144105A1,OCCC1CCCCO1>>O=CCC1CCCCO1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20080139595A1,CC(=O)Nc1ccc(Oc2ccnc3c2c(C2CC2)cn3S(=O)(=O)c2ccc(C)cc2)c(F)c1>>Nc1ccc(Oc2ccnc3[nH]cc(C4CC4)c23)c(F)c1,,CCO,,[Na+].[OH-],,test
US20080181866A1,N[C@@H](CS)C(=O)O.O=C1CCOCC1>>O=C(O)C1CSC2(CCOCC2)N1,,CCO,O,,,test
US20060128710A1,Clc1ncnc2c1CCN(Cc1ccccc1)C2.Nc1ccc(N2CCCCCC2)cc1>>c1ccc(CN2CCc3c(ncnc3Nc3ccc(N4CCCCCC4)cc3)C2)cc1,,C1CCOC1,,c1ccncc1,,test
US20030114443A1,Nc1ccc(Cl)c(Cl)c1.O=C(O)CCl>>O=C(CCl)Nc1ccc(Cl)c(Cl)c1,,C1CCOC1,,,,test
US20020035103A1,O=C(c1ccc(OCCCCl)cc1)C1CC1.OC1CCNC1>>O=C(c1ccc(OCCCN2CCC(O)C2)cc1)C1CC1,,CCC(C)=O,,[I-].[K+],,test
US20050182132A1,N#Cc1ccc(F)cc1Cl.OCCCO>>N#Cc1ccc(OCCCO)cc1Cl,,O,,[Na],,test
US20110039892A1,CC(N)c1ccncc1.Cl.Cl.N#CC(C(N)=O)C1OC(=O)C(Cl)=C1Cl>>CC(c1ccncc1)n1cc(Cl)cc(C(N)=O)c1=N.Cl.Cl,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20060241147A1,O=C(CCl)Nc1ccc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)nc1.OC1CCNCC1>>O=C(CN1CCC(O)CC1)Nc1ccc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)nc1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20050203078A1,COC(=O)c1ccc(N)c(C)c1.O=S(=O)(Cl)CCCCCCl>>COC(=O)c1ccc(NS(=O)(=O)CCCCCCl)c(C)c1,,c1ccncc1,,,,test
US05447960,COC(=O)c1ccccc1Cc1ccccc1.COc1ccc(Br)cc1.COc1ccc([Mg]Br)cc1>>COc1ccc(C(O)(c2ccc(OC)cc2)c2ccccc2Cc2ccccc2)cc1,,C1CCOC1,,[Mg],,test
US20030166650A1,C[C@H](NC(=O)C=Cc1ccccc1)c1cccc(O)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>C[C@H](NC(=O)C=Cc1ccccc1)c1cccc(OS(=O)(=O)C(F)(F)F)c1,,ClCCl,,O,c1ccncc1,test
US05071859,CCOC(=O)[C@@H]1CCCN(CCO/C=C(\c2ccccc2)c2ccccc2C)C1.Cl>>Cc1ccccc1/C(=C/OCCN1CCC[C@@H](C(=O)O)C1)c1ccccc1.Cl,,CC(C)=O,CCO,ClCCl,[Na+].[OH-],test
US04973680,C=C(C)C(=O)Cl.CCO[Si](CCCN)(OCC)OCC>>C=C(C)C(=O)NCCC[Si](OCC)(OCC)OCC,,Cc1ccccc1,,CCN(CC)CC,,test
US20060069110A1,CC(C)(N)CNC(=O)OC(C)(C)C.CN(c1ccnc(F)n1)c1ccnc(-c2ccccc2)n1>>CN(c1ccnc(NC(C)(C)CNC(=O)OC(C)(C)C)n1)c1ccnc(-c2ccccc2)n1,,C1COCCO1,,,,test
US05665718,N/C(=N\O)c1ncn2c1[C@@H]1CCCN1C(=O)c1ccccc1-2.O=C(CCl)OC(=O)CCl>>O=C1c2ccccc2-n2cnc(-c3noc(CCl)n3)c2[C@@H]2CCCN12,,CN(C)C=O,,,,test
US20090069586A1,CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COC(=O)CCCCCCC/C=C\CCCCCCCC)OC(=O)CCCCCCC/C=C\CCCCCCCC>>CCCCCCCC/C=C\CCCCCCCC(=O)OC,,OCC(O)CO,,,,test
US20150315197A1,CC(C)(C)OC(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C(c1n[nH]c2c1CNCC2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1,,ClCCl,,,,test
US04847288,Br[Mg]c1cccs1.COCC#CCN([Si](C)(C)C)[Si](C)(C)C.[NH4+].[OH-]>>C=C=C(CN)c1cccs1.[NH4+].[OH-],Cl[Ni]Cl,CCOC(C)=O,,CCOCC,,test
US20070185101A1,C=C(C)OC(=O)Cl.CC1=C[C@@H]2[C@H](C(C)C)CCC(C)[C@]2(O)[C@@H](OC(=O)[C@@H]2C[C@@]3(O)c4cccc(Cl)c4N(C)O[C@H]3N2)C1O>>C=C(C)OC(=O)O[C@@H]1C(C)=C[C@@H]2[C@H](C(C)C)CC[C@@H](C)[C@]2(O)[C@H]1OC(=O)[C@@H]1C[C@@]2(O)c3cccc(Cl)c3N(C)O[C@H]2N1,CN(C)c1ccncc1,ClCCl,,,,test
US20090176786A1,CI.CN(C(=O)NC(=O)c1c(F)cccc1F)c1ccc(SCC(F)(F)F)cc1F>>CN(C(=O)c1c(F)cccc1F)C(=O)N(C)c1ccc(SCC(F)(F)F)cc1F,,CN1CCCC1=O,O,[H-].[Na+],[Cl-].[NH4+],test
US20070287737A1,NC(=O)c1c(Nc2ccc(I)cc2F)cncc1-c1ccccc1F>>N#Cc1c(Nc2ccc(I)cc2F)cncc1-c1ccccc1F,,C1COCCO1,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,c1ccncc1,test
US20140275065A1,CCOC(=O)c1c(OCC)ncc2ccccc12>>CCOc1ncc2ccccc2c1C(=O)O,,CO,,[Na+].[OH-],,test
US20070213384A1,O=C(NCC(=O)c1ccccc1)Nc1ccc(Cl)c(Cl)c1>>O=c1[nH]cc(-c2ccccc2)n1-c1ccc(Cl)c(Cl)c1,,Cl,,,,test
US20010051631A1,ClCc1cccc2nccn12.NCCCCN.O=C(O)C(F)(F)C(F)(F)F>>O=C(NCCCCNCc1cccc2nccn12)C(F)(F)C(F)(F)F,,CC#N,,CCN(CC)CC,Cl,test
US05723497,CCCCCCCCCCCCCCCCC1CO1.CNCCO>>CCCCCCCCCCCCCCCCC(O)CN(C)CCO,,CCO,,,,test
US20120190675A1,C[C@@H](c1ccc(-c2ccc(C(=O)N(C)C)nc2)cc1)N1CCC2(CCC3(CC2)OCC(C)(C)CO3)OC1=O>>C[C@@H](c1ccc(-c2ccc(C(=O)N(C)C)nc2)cc1)N1CCC2(CCC(=O)CC2)OC1=O,,O,,,,test
US20100173909A1,CCOC(=O)c1sc(Br)nc1-c1cnc(Cl)cn1.Cc1[nH]c(C(=O)N[C@@H]2CCNC[C@@H]2C)c(Cl)c1Cl>>CCOC(=O)c1sc(N2CC[C@@H](NC(=O)c3[nH]c(C)c(Cl)c3Cl)[C@@H](C)C2)nc1-c1cnc(Cl)cn1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,O,test
US20100249123A1,COCCn1cc(C(=O)O)c2cc(F)ccc21.COc1ccc(C(=O)Nc2ccc(C(C)(C)CN)cc2)cc1OC>>COCCn1cc(C(=O)NCC(C)(C)c2ccc(NC(=O)c3ccc(OC)c(OC)c3)cc2)c2cc(F)ccc21,,C1COCCO1,,ClCCCl,On1nnc2ccccc21,test
US20020120148A1,CC(C)(C)OC(=O)COc1ccc2c(c1)CC(NC[C@H](O)c1ccc(OCc3ccccc3)c(NS(C)(=O)=O)c1)CCC2>>CC(C)(C)OC(=O)COc1ccc2c(c1)CC(NC[C@H](O)c1ccc(O)c(NS(C)(=O)=O)c1)CCC2,[Pd],CO,,[H][H],,test
US20110183985A1,BrBr.Cc1ccc2sc(C)nc2c1>>Cc1nc2c(Br)c(C)ccc2s1,,ClC(Cl)Cl,,,,test
US05834493,COc1ccc2[nH]cc(CC3=CCCN(CCc4ccc([N+](=O)[O-])cc4)C3)c2c1>>COc1ccc2[nH]cc(CC3=CCCN(CCc4ccc(N)cc4)C3)c2c1,[Fe],Cl,,,,test
US04284555,C=O.COc1cc2c(cc1Cl)CCNC[C@H]2c1ccccc1>>COc1cc2c(cc1Cl)CCN(C)C[C@H]2c1ccccc1,,O=CO,,,,test
US20120035051A1,CC1(C(=O)CCl)CCCCC1.C[Si](C)(C)c1nccs1>>CC1(C2(c3cncs3)CO2)CCCCC1,,CCOCC,,[Li]CCCC,[Cl-].[NH4+],test
US20130324501A1,CCO.CCOC(OCC)OCC.O=Cc1cc(Br)c([N+](=O)[O-])s1>>CCOC(OCC)c1cc(Br)c([N+](=O)[O-])s1,,CCO,,[Cl-].[NH4+],,test
US20030125370A1,Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1CC(=O)O.O[C@@H]1CCNC1>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1CC(=O)N1CC[C@@H](O)C1,,CN(C)C=O,ClCCl,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20130274253A1,C(#CC1CC1)Nc1ccccc1>>c1ccc2[nH]c(C3CC3)cc2c1,[Cu]I,,,CN(C)C=O,,test
US20150191483A1,CC(C)(C)OC(=O)CN1CCC(c2ccc(C(OCc3c(F)cccc3F)(C(F)(F)F)C(F)(F)F)cc2)(S(=O)(=O)c2ccc(F)cc2)C1.Cl>>Cl.O=C(O)CN1CCC(c2ccc(C(OCc3c(F)cccc3F)(C(F)(F)F)C(F)(F)F)cc2)(S(=O)(=O)c2ccc(F)cc2)C1,,ClCCl,,C1COCCO1,,test
US20100048666A1,CCOC(=O)C(C)c1ccc(C=O)cc1.O=C1SCCC1Br>>CCOC(=O)C(C)c1ccc(C(O)C2CCSC2=O)cc1,[Zn],C1CCOC1,,II,,test
US20150038437A1,CCCC(=O)c1ccc2c(c1)cc1n2CCN(C(=O)OC(C)(C)C)C1.COc1ccc(CN)c(OC)c1>>CCCC(=NCc1ccc(OC)cc1OC)c1ccc2c(c1)cc1n2CCN(C(=O)OC(C)(C)C)C1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,CCN(CC)CC,,test
US04363808,NC(=O)Cc1ccc(OCC2CO2)cc1.NCCCn1cnc2ccccc21>>NC(=O)Cc1ccc(OCC(O)CNCCCn2cnc3ccccc32)cc1,,CO,,,,test
US20100130492A1,C[C@@H]1CNCCN1.Nc1ncc(-c2nc(N3CCOCC3)c3nc(Cl)n(CC(F)(F)F)c3n2)cn1>>C[C@@H]1CN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC(F)(F)F)CCN1,,CO,ClCCl,CN1CCCC1=O,,test
US20120035214A1,CC(C)(C)[Si](C)(C)OCC(F)(F)COCc1ccc(Br)cc1>>OCC(F)(F)COCc1ccc(Br)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06521643B1,COc1ccnc(-c2cc([N+](=O)[O-])cc([N+](=O)[O-])c2C)c1>>COc1ccnc(-c2cc(N)cc(N)c2C)c1,[Pd],C1CCOC1,CCO,,,test
US20080153810A1,O=[N+]([O-])O.O=[N+]([O-])c1ccc2cn[nH]c2c1>>O=[N+]([O-])c1ccc2cn([N+](=O)[O-])nc2c1,,CC(=O)O,,CC(=O)OC(C)=O,,test
US04198409,CCCC(C)=O.CCc1cccc(CC)c1NC(=O)NC(=N)NC>>CCc1cccc(CC)c1-n1cnc(NC)nc1=O,,CCCCCC,,,,test
US20160128984A1,NO.O=Cc1ccc(F)cc1>>O/N=C/c1ccc(F)cc1,,CO,O,Cl,CC(=O)[O-].[Na+],test
US20110257207A1,COC(=O)CC(=O)OC.O=[N+]([O-])c1ccc(Cl)c(Cl)c1>>COC(=O)C(C(=O)OC)c1ccc([N+](=O)[O-])cc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20140309225A1,CC(C)C[C@H](CO)NC(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CC(C)C[C@H](COS(C)(=O)=O)NC(=O)OC(C)(C)C,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20160176817A1,CCOC(=O)C(=O)Cl.Cn1cccc1C(=O)O>>CCOC(=O)C(=O)c1cc(C(=O)O)n(C)c1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20070117854A1,C=O.FC(F)(F)CC(F)(F)c1n[nH]cc1Br>>OCn1cc(Br)c(C(F)(F)CC(F)(F)F)n1,,CC(C)=O,,,,test
US20140142083A1,C=CCBr.COC(=O)c1cc(Cl)cc(NC2CCOCC2)c1C>>C=CCN(c1cc(Cl)cc(C(=O)OC)c1C)C1CCOCC1,,CN(C)C=O,,[H-].[Na+],,test
US03962281,CC(C)SCS(=O)C(C)C.COc1ccc(CBr)cc1OC.ClCCl>>COc1ccc(CC=O)cc1OC,,ClCCl,,C1CCOC1,[H-].[Na+],test
US20100137444A1,CC(C)(C)OC(=O)C1(CCCCBr)CC1.CC(C)(C)OC(=O)C1(CCCCC(=O)CCCCC2(C(=O)OC(C)(C)C)CC2)CC1.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>[C-]#[N+]C(CCCCC1(C(=O)OC(C)(C)C)CC1)(CCCCC1(C(=O)OC(C)(C)C)CC1)S(=O)(=O)c1ccc(C)cc1,,CS(C)=O,O,[H-].[Na+],,test
US20040049008A1,C#CCO.CC(C)(C)OC(=O)NCCC(=O)O>>C#CCOC(=O)CCNC(=O)OC(C)(C)C,,CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20100317656A1,CCOC(=O)c1cn2cc(-c3cccc(CO)c3)ccc2n1>>O=C(O)c1cn2cc(-c3cccc(CO)c3)ccc2n1,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20100174104A1,CC(=O)C(=[N+]=[N-])S(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)C=[N+]=[N-])cc1,,ClCCl,,[Al],,test
US20100096327A1,C=Cc1ccc(CCl)cc1.CCCP(CCC)CCC>>C=Cc1ccc(C[P+](CCC)(CCC)CCC)cc1.[Cl-],,CC#N,,,,test
US06166037,OC1CCN(CC2CN(Cc3ccccc3)CC2c2ccccc2)CC1>>O=C1CCN(CC2CN(Cc3ccccc3)CC2c2ccccc2)CC1,,ClCCl,,CS(C)=O,O=C(Cl)C(=O)Cl,test
US20160272634A1,CC1(C)Cc2cc(Nc3nn([C@@H](CC#N)C4CC4)c4ccnc(OCc5ccccc5)c34)ccc2S1(=O)=O>>CC1(C)Cc2cc(Nc3nn([C@@H](CC#N)C4CC4)c4cc[nH]c(=O)c34)ccc2S1(=O)=O,[Pd],CO,,,,test
US03962224,CCOP(=O)(CN)OCC.O=Cc1ccccc1>>CCOP(=O)(CN=Cc1ccccc1)OCC,,CCO,,,,test
US20040204450A1,CCOC(=O)N1c2ccc(C(F)(F)F)cc2[C@@H](O)C[C@H]1CC.O=S(Cl)Cl>>CCOC(=O)N1c2ccc(C(F)(F)F)cc2C(Cl)C[C@H]1CC,CN(C)C=O,,,,,test
US20100272678A1,COC(=O)c1ccc(C)[se]1.O=[N+]([O-])O>>COC(=O)c1cc([N+](=O)[O-])c(C)[se]1,,CC(=O)OC(C)=O,,,,test
US20100267734A1,CN1CCN(C(C(=O)O)c2cccc3ccccc23)CC1.NCc1cc(Cl)cc(Cl)c1>>CN1CCN(C(C(=O)NCc2cc(Cl)cc(Cl)c2)c2cccc3ccccc23)CC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20080021032A1,COCCCN.CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)Nc2ccn(CCC(=O)O)n2)cc1Cl>>COCCCNC(=O)CCn1ccc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(C)(=O)=O)c(Cl)c2)n1,,ClCCl,,Cc1cccc(C)n1,O=C(Cl)C(=O)Cl,test
US20050176689A1,CN(Cc1cc(C#C[Si](C)(C)C)cc2c1OC(C)(C)CC2(C)C)C1CC1>>C#Cc1cc(CN(C)C2CC2)c2c(c1)C(C)(C)CC(C)(C)O2,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20100273764A1,Cc1nc(-c2cc(Cl)cnc2Nc2cccc3c2cnn3C2CCCCO2)c2ncn(C3CCCCO3)c2n1>>Cc1nc(-c2cc(Cl)cnc2Nc2cccc3[nH]ncc23)c2nc[nH]c2n1,,CO,ClCCl,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US20040092546A1,CCOC(=O)c1c[nH]cc1C(=O)c1cccnc1Cl.NN>>CCOC(=O)c1c[nH]cc1-c1n[nH]c2ncccc12,,CCO,,O,,test
US03952031,CCNCC.CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(C)=O)[C@@]4(C)CC(=O)[C@@H]32)C[C@@H]1OC(=O)CI>>CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(C)=O)[C@@]4(C)CC(=O)[C@@H]32)C[C@@H]1OC(=O)CN(CC)CC,,ClCCl,,O,,test
US20140045746A1,CSCC1CNC1.Cc1nc(F)ccc1Br>>CSCC1CN(c2ccc(Br)c(C)n2)C1,,CCOC(C)=O,CN1CCCC1=O,,,test
US20140315917A1,C=C(C)CNC(=O)NC1CCCCC1>>CC1(C)CNC(=O)N1C1CCCCC1,,O=C(O)C(F)(F)F,,,,test
US20150232464A1,CC(C)(C)OC(=O)N1C(C)(C)OCC1(C)C(=O)NN.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1C(C)(C)OCC1(C)c1nnc(C(F)(F)F)o1,,ClCCl,,CCN(CC)CC,,test
US20100048564A1,COC(=O)c1cccc(O)c1.Cn1c(CO)nc2ccc(Oc3cccc(Cl)c3)cc21>>COC(=O)c1cccc(OCc2nc3ccc(Oc4cccc(Cl)c4)cc3n2C)c1,,ClCCl,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US04451285,CCCNc1c(C)cccc1OCCOCCOC.O=C(Cl)CCl>>CCCN(C(=O)CCl)c1c(C)cccc1OCCOCCOC,,ClCCl,,[Na+].[OH-],,test
US05753594,COC(=O)C1OC1(C)c1cccnc1.Cl[Ti](Cl)(Cl)Cl>>COC(=O)C(O)C(C)(Cl)c1cccnc1,Cl[Ti](Cl)(Cl)Cl,C1CCOC1,,[Cl-].[Li+],,test
US05166204,C=C(CC)c1cc2cc(OC)ccc2n1COC.Cc1ccc(N2C(=O)C=CC2=O)cc1>>CCC1CC2C(=O)N(c3ccc(C)cc3)C(=O)C2c2c1n(COC)c1ccc(OC)cc21,,Cc1ccccc1C,,,,test
US20160016960A1,CCOC(=O)c1cc2nc(C)c([C@H](OC(C)(C)C)C(=O)OCC)c(I)n2n1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc(C(=O)O)nn2c1I,,CCO,,[Na+].[OH-],,test
US20080214622A1,Cc1cc(C)[nH]n1.ClCc1nnc(-c2ccc(I)cc2)o1>>Cc1cc(C)n(Cc2nnc(-c3ccc(I)cc3)o2)n1,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20040180875A1,BrCc1ccccn1.CN1c2c(cc(O)cc2C(F)(F)F)C2CN(C(=O)OC(C)(C)C)CCC21>>CN1c2c(cc(OCc3ccccn3)cc2C(F)(F)F)C2CNCCC21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140094474A1,C[C@H](N)Cn1ccc(-c2cc(F)c(C#N)c(Cl)c2)n1.Cn1cc(-n2ccc(C(=O)O)n2)cn1>>C[C@@H](Cn1ccc(-c2cc(F)c(C#N)c(Cl)c2)n1)NC(=O)c1ccn(-c2cnn(C)c2)n1,,ClCCl,,CN(C)C=O,,test
US20130096113A1,N#Cc1ccc(N)cc1.O=C1CCC(=O)N1Cl>>N#Cc1ccc(N)c(Cl)c1,,CC#N,,,,test
US20050165028A1,C1CCNCC1.O=C(Nc1ccc2c(c1)OCCO2)c1ccc(Br)cc1>>O=C(Nc1ccc2c(c1)OCCO2)c1ccc(N2CCCCC2)cc1,,CCOC(C)=O,CN1CCCC1=O,,,test
US20080058356A1,CS(=O)(=O)c1nc(N)cc(-c2ccco2)n1.c1nc[nH]n1>>Nc1cc(-c2ccco2)nc(-n2cncn2)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100152160A1,COC(=O)C1CN(C(=O)OC(C)(C)C)c2cc(Cl)c(NC(=O)OC(C)(C)C)cc2O1>>CC(C)(C)OC(=O)Nc1cc2c(cc1Cl)N(C(=O)OC(C)(C)C)CC(C(=O)O)O2,,C1CCOC1,O,[Li+].[OH-],,test
US20040002508A1,CC1(C)OC(=O)CC(=O)O1.O=C(O)c1cccs1>>CCOC(=O)CC(=O)c1cccs1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20150175594A1,CCN(CC)S(F)(F)F.OC1CCC(OCc2ccccc2)CC1>>FC1CCC(OCc2ccccc2)CC1,,ClCCl,,,,test
US04999378,COC(=O)c1ccc(OCCCN(CCC(=O)O)c2ccc(Cl)cc2)cc1>>O=C(O)CCN(CCCOc1ccc(C(=O)O)cc1)c1ccc(Cl)cc1,,CO,O,Cl,[Na+].[OH-],test
US20030220364A1,CCOC(=O)C(=O)C(C)Br.Nc1cccnc1N>>CCOC(=O)c1nc2c(N)cccn2c1C,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20120184508A1,C[Si](C)(C)CCOCn1nc(-c2cccc(NCc3cccs3)c2)c2cnc(NCCN3CCOCC3)nc21>>c1cc(NCc2cccs2)cc(-c2n[nH]c3nc(NCCN4CCOCC4)ncc23)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160166560A1,COc1ccc(N2CCC(N(C)C(=O)Cl)CC2)cc1.Oc1cccc(-c2c[nH]cn2)c1>>COc1ccc(N2CCC(N(C)C(=O)n3cnc(-c4cccc(O)c4)c3)CC2)cc1,,ClCCl,c1ccncc1,,,test
US20040019098A1,C1COCCN1.CS(=O)(=O)OCCC1OC(=C2C(=O)Nc3ccccc32)c2ccccc21>>O=C1Nc2ccccc2C1=C1OC(CCN2CCOCC2)c2ccccc21,,C1COCCO1,,,,test
US20090062214A1,C/C=C/O[C@H]1O[C@H](CO)[C@@H](O)[C@H](OCCCCCCCCCC)[C@H]1OCC[C@H](O)CCCCCCCCCCC.CC(C)(C)[Si](C)(C)Cl>>C/C=C/O[C@H]1O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](OCCCCCCCCCC)[C@H]1OCC[C@H](O)CCCCCCCCCCC,CN(C)c1ccncc1,ClCCl,,,,test
US20010023249A1,CON(C)C(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C>>CC(C)C[C@@H](C=O)NC(=O)OC(C)(C)C,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04090026,Cc1[nH]cnc1CSCCN.S=C=S.c1ccncc1>>CNC(=S)NCCSCc1nc[nH]c1C,,c1ccncc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20150353553A1,C1=C(c2ccccn2)CCCC1>>C1CCC(C2CCCCN2)CC1,O=[Pt]=O,CC(=O)O,,,,test
US20110218192A1,CC(=O)c1cc(C)ccc1O.O=Cc1ccccc1>>Cc1ccc2c(c1)C(=O)CC(c1ccccc1)O2,,CCO,O,,,test
US04634692,CCOC(C)OC(C)(C)[C@@H](F)CC[C@@H](CO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC5CCCCO5)C[C@H](OC5CCCCO5)[C@]4(C)[C@H]3CC[C@]12C.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOC(C)OC(C)(C)[C@@H](F)CC[C@@H](COS(=O)(=O)c1ccc(C)cc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC5CCCCO5)C[C@H](OC5CCCCO5)[C@]4(C)[C@H]3CC[C@]12C,,c1ccncc1,,,,test
US20080261941A1,CC(C)(C)OC(=O)N1CCC(=Cc2cccc(Oc3ccc(OCC(F)(F)F)cc3)c2)CC1>>FC(F)(F)COc1ccc(Oc2cccc(C=C3CCNCC3)c2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150322035A1,CC1(C)OB(c2ccc(N)c([N+](=O)[O-])c2)OC1(C)C.N#Cc1cc(I)ccc1F>>N#Cc1cc(-c2ccc(N)c([N+](=O)[O-])c2)ccc1F,Cl[Pd]Cl,,,O=C([O-])[O-].[Na+].[Na+],,test
US20080045493A1,CCC=O.c1ccc(C2CCCNC2)cc1>>CCCN1CCCC(c2ccccc2)C1,,C1CCOC1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20080176857A1,CCc1cc2c(N3CCN(C(=O)Cc4ccccc4)CC3)nc(Cl)nc2s1.CNC(=O)CS>>CCc1cc2c(N3CCN(C(=O)Cc4ccccc4)CC3)nc(SCC(=O)NC)nc2s1,,CN(C)C=O,,,,test
US20150376170A1,CCOC(=O)CC1COc2cc(Br)ccc2N1C(=O)OC(C)(C)C>>CCOC(=O)CC1COc2cc(Br)ccc2N1,,Cl,,C1COCCO1,,test
US20110301167A1,O=C1C(=NNCc2ccc(I)cc2)C(c2ccccc2F)=NN1c1ccccc1F>>O=c1c2nn(Cc3ccc(I)cc3)c3ccccc3c-2nn1-c1ccccc1F,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20160024044A1,CCOC(=O)Cl.CNCC(c1ccc(Cl)c(Cl)c1)C(O)c1ccccc1>>CCOC(=O)NCC(c1ccc(Cl)c(Cl)c1)C(O)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20120114739A1,C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)c1c(C#N)c(N2CCOCC2)nc2c(-c3cnc4ccccc4c3)cnn12>>N#Cc1c(N2CCOCC2)nc2c(-c3cnc4ccccc4c3)cnn2c1N,,CCO,,Cl,,test
US20140148340A1,NNc1ccc(OC(F)(F)F)cc1.O=C(Cl)CCCl>>O=C1CCN(c2ccc(OC(F)(F)F)cc2)N1,,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US20090054402A1,CCOC(=O)c1[nH]c2c(-c3ccc(C(=O)OC(C)(C)C)cc3C)cccc2c1CCCOc1cccc2ccccc12>>CCOC(=O)c1[nH]c2c(-c3ccc(C(=O)O)cc3C)cccc2c1CCCOc1cccc2ccccc12,,ClCCl,O=C(O)C(F)(F)F,,,test
US20080287517A1,CCOC(=O)c1nn(-c2ccc(Cl)cc2C)c(-c2ccc(OCc3ccccc3)cc2)c1C>>Cc1cc(Cl)ccc1-n1nc(C(=O)O)c(C)c1-c1ccc(OCc2ccccc2)cc1,,CCO,O,[Na+].[OH-],,test
US20060106096A1,Cl.Nc1ccc2cc(C(=O)N[C@H]3CN4CCC3CC4)sc2c1.O=C=Nc1ccc(Cl)cc1Cl>>Cl.O=C(Nc1ccc2cc(C(=O)N[C@H]3CN4CCC3CC4)sc2c1)Nc1ccc(Cl)cc1Cl,,C1CCOC1,,CCN(CC)CC,Cl,test
US20130102576A1,COC(=O)CN1C(=O)c2cc(NS(C)(=O)=O)c(OC)cc2C1=O>>COc1cc2c(cc1NS(C)(=O)=O)C(=O)N(CC(=O)O)C2=O,,C1COCCO1,,Cl,,test
US05650412,CC(C)(C)NC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)CCN1C(=O)Cc1ccccc1>>CC(C)(C)NC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)CCN1,[Pd],CO,,[H][H],,test
US20060241118A1,COC(=O)C=C1CCOCC1>>COC(=O)CC1CCOCC1,,CO,,,,test
US20090029955A1,CC1(C)CCc2c(N3CCOCC3)nc(S)c(C#N)c2C1.NC(=O)CCl>>CC1(C)CCc2c(N3CCOCC3)nc3sc(C(N)=O)c(N)c3c2C1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20070281933A1,NC(=O)c1cc(Br)cc2c(C3CCNCC3)n[nH]c12.O=S(=O)(Cl)CCCCl>>NC(=O)c1cc(Br)cc2c(C3CCN(S(=O)(=O)CCCCl)CC3)n[nH]c12,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20100267918A1,CC[C@H](C)[C@H](N)C(=O)O.O=C(Oc1ccc([N+](=O)[O-])cc1)Oc1ccc([N+](=O)[O-])cc1>>CC[C@H](C)[C@H](NC(=O)Oc1ccc([N+](=O)[O-])cc1)C(=O)O,,C1CCOC1,,,,test
US20040209905A1,BrCCCBr.C1COCCN1.CCCNC(=O)Nc1ccc(Oc2ccnc3cc(O)c(OC)cc23)cc1OC>>CCCNC(=O)Nc1ccc(Oc2ccnc3cc(OCCCN4CCOCC4)c(OC)cc23)cc1OC,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20080027070A1,COc1ccc(C(=O)Nc2ccc(Cl)c(C(=O)Nc3cnc(Nc4ccc(S(=O)(=O)C5CCN(C(=O)OC(C)(C)C)CC5)cc4)nc3)c2)cc1.O=C(O)C(F)(F)F>>COc1ccc(C(=O)Nc2ccc(Cl)c(C(=O)Nc3cnc(Nc4ccc(S(=O)(=O)C5CCNCC5)cc4)nc3)c2)cc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20120129870A1,CCCC[Sn](CCCC)(CCCC)c1ncco1.O=C(Cl)C1CC1>>O=C(c1ncco1)C1CC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,,,,test
US04138564,O=C(O)C1CN(C(=O)OCc2ccccc2)CCN1.O=[N+]([O-])c1ccc(F)nc1F>>O=C(O)C1CN(C(=O)OCc2ccccc2)CCN1c1nc(F)ccc1[N+](=O)[O-],,CS(C)=O,,CCN(CC)CC,Cl,test
US20100080770A1,C=CCC(C)(C)CCN.O=C(Cl)Cl>>C=CCC(C)(C)CCN=C=O,,ClCCl,,Cc1ccccc1,O=C([O-])O.[Na+],test
US20050245527A1,CC(C)(C)OC(=O)N1CCC(C(=O)Cc2ccccc2Br)CC1.c1cncc(B2OCCCO2)c1>>CC(C)(C)OC(=O)N1CCC(C(=O)Cc2ccccc2-c2cccnc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],test
US05882628,CC(=O)OC(C)C(=O)Nc1c(I)c(CCC(=O)[O-])c(I)c(NC(=O)C(C)OC(C)=O)c1I.[OH-]>>CC(O)C(=O)Nc1c(I)c(CO)c(I)c(NC(=O)C(C)O)c1I,,CO,O,Cl,,test
US20090111808A1,CC1CCCN1.O[C@@H]1CC[C@@H](c2ccc(OCCCCl)cc2)CC1>>CC1CCCN1CCCOc1ccc([C@@H]2CC[C@@H](O)CC2)cc1,,CC#N,,[Na],,test
US20110065764A1,CCOC(=O)C(=O)CC(=O)c1ccc(C(C)(C)C)cc1.NO>>CCOC(=O)c1cc(-c2ccc(C(C)(C)C)cc2)on1,,CCO,,Cl,,test
US04803241,COC(=O)c1ccc(C=Cc2nc3cc(C)c(C)cc3o2)cc1>>Cc1cc2nc(C=Cc3ccc(C(=O)O)cc3)oc2cc1C,,O,,CC(=O)O,O=S(=O)(O)O,test
US20070203156A1,CC(C)(C)[Si](C)(C)OC(CCCCCCc1ccccc1)c1ncc(-c2ccccc2O)o1>>O=C(CCCCCCc1ccccc1)c1ncc(-c2ccccc2O)o1,,CCOC(C)=O,,,,test
US20030225283A1,CS(=O)(=O)c1ccc([C@@H](CC2CCC(O)C2)C(=O)Nc2cnccn2)cc1Cl>>CS(=O)(=O)c1ccc([C@@H](CC2CCC(=O)C2)C(=O)Nc2cnccn2)cc1Cl,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05719182,CCOC(=O)CC(=O)c1ccccc1.O=Cc1ccc(O)cc1>>CCOC(=O)C(=Cc1ccc(O)cc1)C(=O)c1ccccc1,CC(=O)O,CCO,,C1CCNCC1,,test
US20040138449A1,CNCC(O)c1ccco1.CON(C)C(=O)Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2sc(CCl)cc21>>CON(C)C(=O)Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2sc(CN(C)CC(O)c3ccco3)cc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20080262055A1,C=CCBr.CCOC(=O)c1c(-c2ccc(O)cc2)noc1C>>C=CCOc1ccc(-c2noc(C)c2C(=O)OCC)cc1,,C1CCOC1,CCOC(C)=O,O,O=C([O-])[O-].[Cs+].[Cs+],test
US04336322,CCCCCCCCCCCCCCCCOc1cc(O)c(NC(C)=O)cc1C(C)(CC)CCCC.Cl>>CCCCCCCCCCCCCCCCOc1cc(O)c(N)cc1C(C)(CC)CCCC.Cl,,CCO,,,,test
US06166006,COC(=O)C1=Cc2cc(-c3ccc(N4CCOCC4)cc3)ccc2SCC1>>O=C(O)C1=Cc2cc(-c3ccc(N4CCOCC4)cc3)ccc2SCC1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20090163524A1,CON.O=C(c1ccc(Cl)cc1)C1CC1>>CON=C(c1ccc(Cl)cc1)C1CC1,,c1ccncc1,,Cl,,test
US20160024057A1,CC1(C)CC(Cn2ncc3cc(-c4cnn(C5CCCCO5)c4)ccc32)CN1.O=C(Cl)CCc1ccccc1>>CC1(C)CC(Cn2ncc3cc(-c4cnn(C5CCCCO5)c4)ccc32)CN1C(=O)CCc1ccccc1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20040058937A1,ClCCl.O=C(Cl)C(=O)Cl.O=C(O)C1C=Nc2ccccc2C1=O>>O=C(Cl)c1cnc2ccccc2c1Cl,CN(C)C=O,,,,,test
US20030045558A1,CCOC(=O)C(C)(C)Oc1ccc(OCCc2nc(-c3cccc(-c4ccc(F)cc4)c3)oc2C)cc1>>Cc1oc(-c2cccc(-c3ccc(F)cc3)c2)nc1CCOc1ccc(OC(C)(C)C(=O)O)cc1,,CO,,[Na+].[OH-],,test
US05070087,CCOC(=O)Cc1ccc(N)cc1.OC(c1ccc(F)cc1)(c1ccc(F)cc1)C1CCN(CCCCl)CC1>>CCOC(=O)Cc1ccc(NCCCN2CCC(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US05134138,CC(C)(C)OC(=O)C(C)(C)ON=C(C(=O)O)c1csc(N)n1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)Nc1nc(C(=NOC(C)(C)C(=O)OC(C)(C)C)C(=O)O)cs1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US04276417,C1=CCNCC1.Nc1nc(N)nc(Cl)n1>>Nc1nc(N)nc(N2CC=CCC2)n1,,CCCCO,,O=C([O-])O.[Na+],,test
US20100004301A1,CC(C)(C)c1ccc2oc(-c3cc(C(=O)O)cc([N+](=O)[O-])c3)nc2c1>>CC(C)(C)c1ccc2oc(-c3cc(CO)cc([N+](=O)[O-])c3)nc2c1,,C1CCOC1,,Cl,,test
US20060199817A1,C1CCNCC1.Clc1nncc2cc(Br)ccc12>>Brc1ccc2c(N3CCCCC3)nncc2c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040157839A1,CCNC1(C(N)=O)CCNCC1.Cc1nc(Cl)n2nc(-c3ccccc3Cl)c(I)c2n1>>CCNC1(C(N)=O)CCN(c2nc(C)nc3c(I)c(-c4ccccc4Cl)nn23)CC1,,C1CCOC1,,CCN(CC)CC,,test
US04317820,C1CNCCN1.O=C(O)c1cn2c3c(c(Cl)ccc3c1=O)CC2>>Cl.O=C(O)c1cn2c3c(c(N4CCNCC4)ccc3c1=O)CC2,,CS(C)=O,,,,test
US05618801,CCOP(=O)(Cc1ccc(C(=O)Cl)cc1)OCC.N#Cc1cc(Br)ccc1N>>CCOP(=O)(Cc1ccc(C(=O)Nc2ccc(Br)cc2C#N)cc1)OCC,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US20100152187A1,CCOC(=O)c1ccc(Br)cc1.Oc1ccccn1>>CCOC(=O)c1ccc(-n2ccccc2=O)cc1,[Cu]I,N,,O=C([O-])[O-].[K+].[K+],,test
US08193118B2,Cc1cccc(CN)c1C.O=C=NCCCl>>Cc1cccc(CNC2=NCCO2)c1C,,C1COCCO1,CCOC(C)=O,[Na+].[OH-],,test
US05102914,CS(=O)(=O)Nc1ccc(CCNCc2ccccc2)cc1>>CS(=O)(=O)Nc1ccc(CCN)cc1,[Pd],CO,,,,test
US20100120798A1,CC(C)(C)OC(=O)NCC1(C(=O)O)CCN(c2ncnc3[nH]ccc23)CC1.CCN(C(C)C)C(C)C.Nc1nc(-c2cccnc2)cs1>>CCc1ccccc1NC(=O)C1(CNC(=O)OC(C)(C)C)CCN(c2ncnc3[nH]ccc23)CC1,,CC(=O)N(C)C,CCOC(C)=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20030078287A1,Nc1ccccc1C=Cc1ccccc1.O=C(Cl)c1sccc1OC(F)F>>O=C(Nc1ccccc1)C1(C=Cc2ccccc2)SC=CC1OC(F)F,,Cc1ccccc1,,CCN(CC)CC,O,test
US05360795,N#CBr.Nc1cc(Cl)c(Cl)c(Cl)c1N>>Nc1nc2cc(Cl)c(Cl)c(Cl)c2[nH]1,,CO,O,CC#N,,test
US20160002169A1,CC(C)(C)OC(=O)C=C1CC(C(=O)O)C1.COc1ccc2c(c1)CCN[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1>>COc1ccc2c(c1)CCN(C(=O)C1CC(=CC(=O)OC(C)(C)C)C1)[C@H]2C(=O)Nc1cc(F)c([Si](C)(C)C)c(F)c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030004161A1,CC(=O)Nc1ccc(S)cc1.Cc1cc(Nc2nc(Cl)nc3ccccc23)[nH]n1>>CC(=O)Nc1ccc(Sc2nc(Nc3cc(C)n[nH]3)c3ccccc3n2)cc1,,CC(C)(C)O,,CCOCC,O=C([O-])[O-].[K+].[K+],test
US20150284411A1,O=CC[C@@]1(O)CO[C@@H]2[C@H](Oc3nc4nc(-c5ccc(-c6ccccc6)cc5)c(Cl)cc4[nH]3)CO[C@@H]21>>OCC[C@@]1(O)CO[C@@H]2[C@H](Oc3nc4nc(-c5ccc(-c6ccccc6)cc5)c(Cl)cc4[nH]3)CO[C@@H]21,,CO,,[BH4-].[Na+],,test
US04007219,CC(=O)OC(C)=O.NCC1CN=C(c2ccccc2F)c2cc(Cl)ccc2N1>>CC(=O)NCC1CN=C(c2ccccc2F)c2cc(Cl)ccc2N1,,ClCCl,,O=C([O-])O.[Na+],,test
US20070049616A1,CCCC(=O)Cl.N#Cc1ccc(C2CCc3cncn32)c(N)c1>>CCCC(=O)Nc1cc(C#N)ccc1C1CCc2cncn21,,CN(C)C=O,,CCN(CC)CC,,test
US20090036431A1,C=C1CN[C@H](C(=O)OC)C1.COc1cc(C(=O)O)c([N+](=O)[O-])cc1OCCCCCBr>>C=C1C[C@@H](C(=O)OC)N(C(=O)c2cc(OC)c(OCCCCCBr)cc2[N+](=O)[O-])C1,CN(C)C=O,C1CCOC1,O,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US07524840B2,COCCO.Fc1cc2c(cc1F)C(c1ccccc1Cl)=NCC(=S)N2>>COCCOc1cc2c(cc1F)C(c1ccccc1Cl)=NCC(=S)N2,,CCOC(C)=O,,[H-].[Na+],,test
US20110105436A1,CCOC(=O)c1sc(Nc2cccc(C)c2)nc1-c1ccncc1>>Cc1cccc(Nc2nc(-c3ccncc3)c(C(=O)O)s2)c1,,CO,,[Na+].[OH-],,test
US06005000,CC1(c2ccccc2)OC(=O)C(O)=C1O.CCC[Mg]Br.CCOC(=O)C(=O)c1ccc(CC(C)C)cc1>>CCCC1(c2ccc(CC(C)C)cc2)OC(=O)C(OCc2ccccc2)=C1O,,C1CCOC1,,,,test
US20030065179A1,CCCC(=O)O[C@H](C)c1nccc(Cl)n1.c1ccc2sc(-c3nnc4n3CCNC4)nc2c1>>CCCC(=O)O[C@H](C)c1nccc(N2CCn3c(nnc3-c3nc4ccccc4s3)C2)n1,,CCCCO,,CCN(CC)CC,,test
US04352795,CSc1nc(NN)c2ccn([C@@H]3O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@@H]3OCc3ccccc3)c2n1>>Nc1ncnc2c1ccn2[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1,[Ni],CCO,,,,test
US20120142717A1,CCOC(=O)c1c[nH]c(=S)[nH]c1=O.FC(F)(F)c1cc(Oc2ccc(CCl)cc2)ccc1Cl>>CCOC(=O)c1c[nH]c(SCc2ccc(Oc3ccc(Cl)c(C(F)(F)F)c3)cc2)nc1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US06255496B1,CCCCCCCCCCCCI.COC(=O)[C@@H]1C[C@@H](O)CN1>>CCCCCCCCCCCCN1C[C@H](O)C[C@H]1C(=O)OC,,CCOC(C)=O,CO,Cl,O=C([O-])[O-].[K+].[K+],test
US20140005213A1,COCCOc1ccc2ccc(C)nc2c1.O=[Se]=O>>COCCOc1ccc2ccc(C=O)nc2c1,,C1COCCO1,O,,,test
US06107308,CC(C)(C)OC(=O)N1CCC(O)(Cc2ccc3ccccc3n2)CC1>>CC(C)(C)OC(=O)N1CC=C(Cc2ccc3ccccc3n2)CC1,,C1CCOC1,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20100267687A1,Br.C[C@@H]1CCCN1CCCOc1ccc(-n2cc(C(=O)N3CCOCC3)cn2)cc1>>Br.C[C@@H]1CCCN1CCCOc1ccc(-n2cc(C(=O)N3CCOCC3)cn2)cc1,,CCO,,,,test
US20040220193A1,CC(C)(C)OC(=O)N1CCN(CCCc2cccs2)CC1>>c1csc(CCCN2CCNCC2)c1,,CO,,CCOC(C)=O,Cl,test
US20140171390A1,BrCc1ccccc1.CC(C)(C)OC(=O)NC1CCC(CC(=O)O)CC1>>N[C@@H]1CC[C@@H](CC(=O)OCc2ccccc2)CC1,,CCOCC,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20040106795A1,CCCCO.O=Cc1cc(I)c(O)c([N+](=O)[O-])c1>>CCCCOc1c(I)cc(C=O)cc1[N+](=O)[O-],,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04349568,CC(=O)Cl.CS(=O)(=O)c1ccc(Oc2ccccc2)cc1>>CC(=O)c1ccc(Oc2ccc(S(C)(=O)=O)cc2)cc1,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20060088573A1,CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O>>CCCCCCCC(=O)O,,O,,,,test
US05994368,Cc1ncccc1CC(=O)OCc1ccccc1>>Cc1ncccc1CC(=O)O,[Pd],CO,O,,,test
US05972949,CC(C)(C)C(=O)Oc1ccc(CBr)cc1Cl.c1c[nH]nn1>>CC(C)(C)C(=O)Oc1ccc(Cn2nccn2)cc1Cl,,CN(C)C=O,,[H][H],[H-].[Na+],test
US04072674,COC(=O)[C@H]1[C@@H](N=[N+]=[N-])C(=O)N1Cc1ccc(OC)cc1OC>>COC(=O)[C@H]1[C@@H](N)C(=O)N1Cc1ccc(OC)cc1OC,[Pd],CCO,,[H][H],,test
US20050148624A1,CC(=O)c1oc(=O)c2ccc(Br)cc2c1-c1ccccc1.CCOC(=O)C1CCN(S(=O)(=O)c2ccc(CN)cc2)CC1>>CCOC(=O)C1CCN(S(=O)(=O)c2ccc(Cn3c(C(C)=O)c(-c4ccccc4)c4cc(Br)ccc4c3=O)cc2)CC1,,CO,,CCN(CC)CC,,test
US20150210678A1,CC(C)c1ccc(Cl)cc1C=NO>>CC(C)c1ccc(Cl)cc1CN,,C1CCOC1,,B,,test
US20060194837A1,C1CCOC1.CNCC(O)c1ccc(SC)cc1.CSc1ccc(C(O)CN(C)Cc2cccc(O)c2)cc1.O=Cc1cccc(O)c1>>CSc1ccc(C2CN(C)Cc3cc(OCC4CN(C5CC5)C4)ccc32)cc1,,C1CCOC1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160060260A1,CCCBr.Oc1cccc(O)c1Cl>>CCCOc1cccc(O)c1Cl,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US05177095,CCCCc1nnc(SCc2ccc([N+](=O)[O-])cc2)n1Cc1ccc(OC(c2ccccc2)c2nnn[nH]2)cc1.OO>>CCCCc1nnc(S(=O)Cc2ccc([N+](=O)[O-])cc2)n1Cc1ccc(OC(c2ccccc2)c2nnn[nH]2)cc1,,CC(=O)O,,,,test
US20080275043A1,CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@H](N2CCC(Cc3c(Cl)cc(OCc4ccccc4)cc3Cl)C2=O)CC1>>O=C1C(Cc2c(Cl)cc(OCc3ccccc3)cc2Cl)CCN1[C@@H]1CC[C@H](O)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090291941A1,COc1ccc(CN)c(OC)c1.O=c1c2cc(Cl)ncc2ccc2ncc(Cl)cc12>>COc1ccc(CNc2cc3c(=O)c4cccnc4ccc3cn2)c(OC)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US03996376,O=[N+]([O-])O.OCC1COC(C(F)(F)Cl)(C(F)(F)Cl)O1>>O=[N+]([O-])OCC1COC(C(F)(F)Cl)(C(F)(F)Cl)O1,,O,,CC(=O)OC(C)=O,,test
US20030096826A1,CCOC(=O)/N=N/C(=O)OCC.Nc1ccc([N+](=O)[O-])cc1O.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>Nc1ccc([N+](=O)[O-])cc1OCCc1cccc2ccccc12,,C1CCOC1,,,,test
US05545750,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](Cc1ccccc1)[C@H](O)[C@@H](O)[C@@H](N)Cc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C,,ClCCl,,,,test
US20090054508A1,Cn1cccc1C(=O)Cl.Nc1cccc(/C=C/c2n[nH]c3ccccc23)c1O>>Cn1cccc1-c1nc2cccc(/C=C/c3n[nH]c4ccccc34)c2o1,,C1COCCO1,,O=C([O-])O.[Na+],,test
US20010027174A1,BrP(Br)Br.CC(C)(C)OC(=O)n1ccc2c(CO)cccc21>>CC(C)(C)OC(=O)n1ccc2c(CBr)cccc21,,CCOCC,ClCCl,O=C([O-])O.[Na+],,test
US20100305100A1,CC(C)OC(=O)Cl.N#Cc1c(-c2ccc(N)cc2)n(C2CCC2)c2cc(OC3CCOCC3)ccc12>>CC(C)OC(=O)Nc1ccc(-c2c(C#N)c3ccc(OC4CCOCC4)cc3n2C2CCC2)cc1,,CCOC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05543078,CCCCCC[C@@H](C)O.Oc1ccc(OCc2ccccc2)cc1>>CCCCCC[C@H](C)Oc1ccc(OCc2ccccc2)cc1,O,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140031360A1,CC(C)Oc1cncc(-c2ccc3[nH]cc(I)c3c2)n1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)n2cc(I)c3cc(-c4cncc(OC(C)C)n4)ccc32)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20100272680A1,CI.O=C1NCCN1C1CCN(Cc2ccccc2)CC1>>CN1CCN(C2CCN(Cc3ccccc3)CC2)C1=O,,CN(C)C=O,,O,[H-].[Na+],test
US20060247305A1,COc1c(OC)c(OC)c2c(=O)c(C(C)=O)c(C)oc2c1CC(C)C>>COc1c(OC)c(OC)c2c(=O)cc(C)oc2c1CC(C)C,,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US06251911B1,Nc1n[nH]c2ncnc(Nc3cccc(Cl)c3)c12.O=Cc1nccs1>>Clc1cccc(Nc2ncnc3[nH]nc(N=Cc4nccs4)c23)c1,,CO,,CC(=O)O,,test
US05550233,CCC1CCN2C(=O)C(=O)C3(O)OC(C(OC)CC(C)CC(C)=CCC(=O)CC(O[Si](C)(C)C(C)(C)C)C(C)C(C(C)=CC4CCC(CCC(O)c5cc(C)cc(C)c5)(O[Si](CC)(CC)CC)C(OC)C4)OC(=O)C2C1)C(OC)CC3C>>CCC1CCN2C(=O)C(=O)C3(O)OC(C(OC)CC(C)CC(C)=CCC(=O)CC(O)C(C)C(C(C)=CC4CCC(O)(CCC(O)c5cc(C)cc(C)c5)C(OC)C4)OC(=O)C2C1)C(OC)CC3C,,CC#N,,,,test
US20050043537A1,COCCOc1ccc([N+](=O)[O-])cc1I>>COCCOc1ccc(N)cc1I,[Fe],CCO,,O,[Cl-].[NH4+],test
US20050090533A1,CN(C(=O)OC(C)(C)C)c1cnc(Cl)cc1I.OC[C@@H]1C[C@@H](O)CN1>>CN(C(=O)OC(C)(C)C)c1cnc(N2C[C@H](O)C[C@H]2CO)cc1I,,CS(C)=O,,,,test
US06229011B1,COC(=O)[C@@H](N)Cc1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1.O=C(Nc1cccc(O)c1)c1ccc(C(=O)O)c(Cl)c1>>COC(=O)[C@H](Cc1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1)NC(=O)c1ccc(C(=O)Nc2cccc(O)c2)cc1Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05190971,COc1cc(C)c(Br)c2c1Sc1ccc(C(O)CC(C)C)c(OC)c1C(=O)OC2>>COc1cc(C)c(Br)c2c1Sc1ccc(C(=O)CC(C)C)c(OC)c1C(=O)OC2,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20160046596A1,CC(C)(C)OC(=O)Nc1sc2cnccc2c1N(C(=O)OC(C)(C)C)c1ccc(F)c(Cl)c1>>Nc1sc2cnccc2c1Nc1ccc(F)c(Cl)c1,,C1COCCO1,ClCCl,Cl,N,test
US20110294776A1,CC1(C)C(=O)C(Br)C(=O)C1Br.CCOC(=O)C1CC1Cc1ccc2c(N)ncnn12>>CCOC(=O)C1CC1Cc1cc(Br)c2c(N)ncnn12,,C1CCOC1,,,,test
US20120157487A1,N#Cc1ccc(SCc2ccccc2)c(N)c1.O=S(=O)(Cl)c1cc2ccccc2o1>>N#Cc1ccc(SCc2ccccc2)c(NS(=O)(=O)c2cc3ccccc3o2)c1,,c1ccncc1,,,,test
US20030166639A1,CC(C)(C)OC(=O)Nc1cc(Cl)c(C(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-c2cccnc2)c1>>O=C1CC(c2cccc(-c3cccnc3)c2)=Nc2cc(Cl)c(C(F)(F)F)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120264749A1,CC(=O)OC/C=C\CCC(=O)[O-].CC(C)(C)OC(=O)N1CCC(O)(CNCc2ccccc2)CC1>>C=CC1CN(Cc2ccccc2)CC2(CCN(C(=O)OC(C)(C)C)CC2)O1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090137558A1,CCO/C=C/C(=O)C(F)(F)F.CCOC(=O)/C=C(/C)N>>CCOC(=O)c1ccc(C(F)(F)F)nc1C,,CC(=O)O,,O,,test
US20090176778A1,Cc1cc(C)c(S(=O)(=O)ON)c(C)c1.Clc1cc(Br)ccn1>>Cc1cc(C)c(S(=O)(=O)[O-])c(C)c1.N[n+]1ccc(Br)cc1Cl,,ClCCl,,,,test
US20090105214A1,CN(CCO[Si](C)(C)C(C)(C)C)C(=O)c1ccc(F)c(Cl)c1F.COC(=O)c1cc(O)cc(O[C@H]2CCOC2)c1>>COC(=O)c1cc(Oc2ccc3c(c2Cl)OCCN(C)C3=O)cc(O[C@H]2CCOC2)c1,,CC#N,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US20020173653A1,CC(C)Cn1cnc2c(N)nc3cccnc3c21>>CC(C)Cn1cnc2c(N)nc3c(c21)NCCC3,O=[Pt],O=C(O)C(F)(F)F,,[H][H],,test
US20050191238A1,C1=COCCC1.CC(C)(C)c1ccc(C(O)CO[Si](C)(C)C(C)(C)C)cc1>>CC(C)(C)c1ccc(C(CO[Si](C)(C)C(C)(C)C)OC2CCCCO2)cc1,,ClCCl,,Cc1ccccc1S(=O)(=O)O,,test
US20160002248A1,CC(C)(C)OC(=O)c1cn(CC(O)COCc2ccccc2)nn1.CCN(CC)S(F)(F)F>>CC(C)(C)OC(=O)c1cn(CC(F)COCc2ccccc2)nn1,,ClCCCl,,,,test
US20060063812A1,CC(C)(C)OC(=O)N(Cc1coc(-c2cc3cc(OC(F)(F)F)ccc3[nH]2)n1)c1ccc(CCCCn2ccnn2)cc1>>FC(F)(F)Oc1ccc2[nH]c(-c3nc(CNc4ccc(CCCCn5ccnn5)cc4)co3)cc2c1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20160185814A1,CC(C)(C)OC(=O)NCCOCCOCCN.O=C(CI)OC(=O)CI>>CC(C)(C)OC(=O)NCCOCCOCCNC(=O)CI,,CCOCC,,CCOC(C)=O,CO,test
US20120202785A1,NC1CCC1.O=[N+]([O-])c1ccc(F)cc1F>>O=[N+]([O-])c1ccc(F)cc1NC1CCC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20130244958A1,CC(Cl)OC(=O)Cl.COCCOCCOCCOCCOCCO>>COCCOCCOCCOCCOCCOC(=O)OC(C)Cl,,ClCCl,,c1ccncc1,,test
US06235771B1,COC(=O)C1=Cc2cc(-c3ccc(OC)cc3)ccc2S(=O)(=O)CC1>>COc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCS3(=O)=O)cc1,,COCCOC,,Cl,,test
US20070105913A1,CCCCc1ccc(C#Cc2ccc(CN(C(=O)c3ccc(C(C)(C)C)cc3)c3ccc4c(c3)C(=O)OC(C)(C)O4)cc2)cc1>>CCCCc1ccc(C#Cc2ccc(CN(C(=O)c3ccc(C(C)(C)C)cc3)c3ccc(O)c(C(=O)O)c3)cc2)cc1,,CCO,,[Na+].[OH-],,test
US05360795,CC(=O)OC[C@H]1O[C@@H](n2c(Cl)nc3cc(Cl)c(Cl)cc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O.N>>Nc1nc2cc(Cl)c(Cl)cc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O,,CO,,,,test
US04124716,CCN.ClCCOC(=C1C2CC3C(C2)C13)c1ccccc1>>CCNCCOC(=C1C2CC3C(C2)C13)c1ccccc1,,c1ccccc1,,,,test
US04062978,CC(=O)CC(C)=O.O=C(c1ccccc1)c1cccc(CBr)c1>>CC(=O)CCc1cccc(C(=O)c2ccccc2)c1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20110105460A1,COC(=O)C(Br)C(=O)C1CC1.NC(N)=S>>Br.COC(=O)c1sc(N)nc1C1CC1,,CCO,,,,test
US20160122336A1,CCN(CC)C(=O)c1nc(C(=O)N2CCS(=O)(=NC(=O)C(F)(F)F)CC2)sc1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)c(Cl)c1Cl>>CCN(CC)C(=O)c1nc(C(=O)N2CCS(=N)(=O)CC2)sc1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)c(Cl)c1Cl,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20100323994A1,CN(C)S(=O)(=O)Cl.COc1ccc(CN(c2cc(N[C@@H]3CC[C@@H](N)CC3)nn3c(C(=O)Nc4ccncc4F)cnc23)C2CC2)cc1>>CN(C)S(=O)(=O)N[C@@H]1CC[C@@H](Nc2cc(NC3CC3)c3ncc(C(=O)Nc4ccncc4F)n3n2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20100016371A1,CCOC(=O)c1csc(-n2cc(CC(C)C)c3ccc(F)cc32)n1>>CC(C)Cc1cn(-c2nc(C(=O)O)cs2)c2cc(F)ccc12,,CCO,,[Na+].[OH-],,test
US20060229329A1,COC(OC)C(=O)C=CN(C)C.N=C(N)Nc1ccccc1>>COC(OC)c1ccnc(Nc2ccccc2)n1,,CC(=O)N(C)C,,O=C(O)O,,test
US06498254B1,CC(=O)OO.O=[N+]([O-])c1cc(CS(=O)c2cccc[n+]2[O-])cc([N+](=O)[O-])c1>>O=[N+]([O-])c1cc(CS(=O)(=O)c2cccc[n+]2[O-])cc([N+](=O)[O-])c1,,CC(=O)O,,,,test
US20040082542A1,CC=O.CCN(CC)CCCOc1ccc(-c2cn(-c3ccc(Oc4ccc(Cl)cc4)cc3)c(CC3CCNCC3)n2)cc1>>CCN(CC)CCCOc1ccc(-c2cn(-c3ccc(Oc4ccc(Cl)cc4)cc3)c(CC3CCN(CC)CC3)n2)cc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20060189627A1,CC(=O)c1ccncc1.COC(OC)N(C)C>>CN(C)/C=C/C(=O)c1ccncc1,,Cc1ccccc1,,CCOCC,,test
US20110313002A1,COc1ccc(OC)c2c1CC1=C(O2)C(=O)N([C@@H](CC(C)C)C(=O)O)C1.Nc1ccc(Cl)cn1>>COc1ccc(OC)c2c1CC1=C(O2)C(=O)N([C@@H](CC(C)C)C(=O)Nc2ccc(Cl)cn2)C1,,C1CCOC1,O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06498165B1,C=C[Sn](CCCC)(CCCC)CCCC.C[C@H](Nc1nccc(-n2cnc3cc(I)ccc32)n1)c1ccccc1>>C=Cc1ccc2c(c1)ncn2-c1ccnc(N[C@@H](C)c2ccccc2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20120214803A1,O=[N+]([O-])c1c(C(O)c2ccc(C(F)(F)F)nc2)ccc2cccnc12>>O=C(c1ccc(C(F)(F)F)nc1)c1ccc2cccnc2c1[N+](=O)[O-],,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20150158851A1,C=CC(=O)c1ccccc1.FC1(F)CNC1>>O=C(CCN1CC(F)(F)C1)c1ccccc1,,CO,,,,test
US20140315888A1,CC(C)(C)OC(=O)NC1CNC1.Clc1cnc2nc(Cl)c(Cl)nc2c1>>CC(C)(C)OC(=O)NC1CN(c2nc3ncc(Cl)cc3nc2Cl)C1,,ClCCl,,[Cl-].[NH4+],,test
US20090324581A1,COC(=O)c1ccc(C(C)C)c(C(F)(F)F)c1>>CC(C)c1ccc(CO)cc1C(F)(F)F,,C1CCOC1,,Cl,[BH4-].[Li+],test
US20040167158A1,O=CCc1ccc(Br)cc1NC1CCOCC1>>Brc1ccc2ccn(C3CCOCC3)c2c1,,CO,Cl,,,test
US20020128301A1,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.Oc1cccc(O)c1>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)Oc1cccc(O)c1,CN(C)c1ccncc1,CN(C)C=O,,,,test
US20070167423A1,CS(=O)(=O)OCCc1cccc(N2CCCC2=O)c1.Cc1ccc2c(N3CCN(CCc4cccc(N)c4)CC3)cccc2n1>>Cc1ccc2c(N3CCN(CCc4cccc(N5CCCC5=O)c4)CC3)cccc2n1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20140142114A1,CC(C)(C)OC(=O)COC1CCC(Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)CC1>>O=C(O)COC1CCC(Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090118499A1,COC(=O)[C@H]1C[C@@H](O)C1.Clc1ncnc2[nH]cc(I)c12>>COC(=O)[C@@H]1C[C@@H](n2cc(I)c3c(Cl)ncnc32)C1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140274933A1,CI.Cc1nc2ccc(NC(=O)C(F)(F)F)cc2o1>>Cc1nc2ccc(N(C)C(=O)C(F)(F)F)cc2o1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05556977,COC(=O)COc1ccc(C(=O)C(C)(C)Br)cc1.c1cc(N2CCNCC2)ccn1>>COC(=O)COc1ccc(C(=O)C(C)CN2CCN(c3ccncc3)CC2)cc1,,CC#N,,,,test
US20100280013A1,COc1ccc(COc2coc(CO)cc2=O)cc1.[NH4+]>>COc1ccc(COc2c[nH]c(CO)cc2=O)cc1,,CCO,,,,test
US20160002177A1,COc1cc(Br)cc2c(=O)[nH]cnc12.C[Si](C)(C)CCOCCl>>COc1cc(Br)cc2c(=O)n(COCC[Si](C)(C)C)cnc12,,CN(C)C=O,,[H-].[Na+],,test
US20120252807A1,C[C@H](N)c1ccccc1.O=CC1CCN(C(=O)c2cc3ccccc3n2Cc2ccc(F)cc2)CC1>>C[C@H](NCC1CCN(C(=O)c2cc3ccccc3n2Cc2ccc(F)cc2)CC1)c1ccccc1,,C1CCOC1,,CC(=O)O,[BH3-]C#N.[Na+],test
US20080293782A1,CC(=O)Oc1ccc(OCc2ccccc2)cc1.O=[N+]([O-])O>>CC(=O)Oc1ccc(OCc2ccccc2)c([N+](=O)[O-])c1,,ClCCl,,,,test
US20050026964A1,CCOC(=O)c1cnc(Cl)cc1Cl.Cc1ccc(N)c(F)c1>>CCOC(=O)c1cnc(Cl)cc1Nc1ccc(C)cc1F,,CCO,,Cl,,test
US20130053345A1,CN(C)S(=O)(=O)Cl.Fc1cnc(N2CCC(Oc3nc4ccc(C5=CCNCC5)cc4s3)CC2)nc1>>CN(C)S(=O)(=O)N1CC=C(c2ccc3nc(OC4CCN(c5ncc(F)cn5)CC4)sc3c2)CC1,,ClCCl,,CCN(CC)CC,,test
US20090176774A1,CCN=C=O.COc1cc2c(Oc3ccc4cc(N)ccc4c3)ccnc2cc1OCCCN1CCOCC1>>CCNC(=O)Nc1ccc2cc(Oc3ccnc4cc(OCCCN5CCOCC5)c(OC)cc34)ccc2c1,,CN(C)C=O,,CCN(CC)CC,,test
US05308830,CCN(CC)C(=O)Cl.O=S(=O)(CC1CCC1)c1nc[nH]n1>>CCN(CC)C(=O)n1cnc(S(=O)(=O)CC2CCC2)n1,,c1ccncc1,,Cl,,test
US20040058907A1,O=C(Cl)c1ccccc1.O=C(NCC1CN(Cc2ccc(Cl)c(Cl)c2)CCO1)NC1CCNCC1>>O=C(NCC1CN(Cc2ccc(Cl)c(Cl)c2)CCO1)NC1CCN(C(=O)c2ccccc2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20090170921A1,CC(=O)Cl.COCCn1c(-c2ccc(C(C)C)cc2)nc2cc(C(O)c3ccccc3)cc(OC)c21>>COCCn1c(-c2ccc(C(C)C)cc2)nc2cc(C(OC(C)=O)c3ccccc3)cc(OC)c21,,ClCCl,,CCN(CC)CC,,test
US20030100556A1,CN1CCN(c2cccc3c2C[C@H](N)CO3)CC1.O=C(O)c1ccc[nH]1>>CN1CCN(c2cccc3c2C[C@H](NC(=O)c2ccc[nH]2)CO3)CC1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20110251173A1,CC(C)(C)[Si](C)(C)OCCNc1ccc(Br)cc1.Cc1nc(Cl)c(C(=O)Cl)c(Cl)n1>>Cc1nc(Cl)c(C(=O)N(CCO[Si](C)(C)C(C)(C)C)c2ccc(Br)cc2)c(Cl)n1,,C1CCOC1,,CCN(CC)CC,,test
US20080064872A1,CCC(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)c(-c2ccccc2)n1.CON>>CCC(=NOC)c1ccc(-c2ccc(C(F)(F)F)cc2)c(-c2ccccc2)n1,,CCO,,Cl,c1ccncc1,test
US04356302,N#CC(=C1CSc2ccccc2N1)c1ccc(Cl)cc1.O=S(=O)(O)O>>NC(=O)C(=C1CSc2ccccc2N1)c1ccc(Cl)cc1,,O,,,,test
US20010039344A1,COC(=O)Cc1ccc(C(F)(F)F)c(F)c1.ICC1CCCC1>>COC(=O)C(CC1CCCC1)c1ccc(C(F)(F)F)c(F)c1,,C1CCOC1,CN1CCCN(C)C1=O,CC(C)NC(C)C,[Li]CCCC,test
US20080207654A1,CCCCc1nc(C)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.OCc1csc2ccc(Cl)cc12>>CCCCc1nc(C)n(Cc2csc3ccc(Cl)cc23)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1,,C1CCOC1,CCOC(C)=O,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US07091199B1,BrCCCOc1cccc(-c2noc3ccsc23)c1.COc1cccc(CN)c1>>COc1cccc(CNCCCOc2cccc(-c3noc4ccsc34)c2)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090264445A1,CC(=O)c1cccc(O)c1F.C[Mg]Br>>CC(C)(O)c1cccc(O)c1F,,C1CCOC1,CCOCC,Cl,,test
US20050171103A1,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(-c2cnc(Cl)nc2)cc1.NCCCN1CCCCC1>>Nc1ccccc1NC(=O)c1ccc(-c2cnc(NCCCN3CCCCC3)nc2)cc1,,CC(=O)N(C)C,,,,test
US20040254233A1,CCI.O=C(O)C1CCC1>>CCC1(C(=O)O)CCC1,,C1CCOC1,,Cl,CC(C)[N-]C(C)C.[Li+],test
US20070078160A1,CCN1C(=O)CC(C)(C)c2cc(C)c(Br)cc21.O=Cc1ccc(OC(F)(F)F)c(B(O)O)c1>>CCN1C(=O)CC(C)(C)c2cc(C)c(-c3cc(C=O)ccc3OC(F)(F)F)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20090099176A1,CCOC(=O)c1cc2cc(Cl)ncc2[nH]1>>O=C(O)c1cc2nc(Cl)ccc2[nH]1,,CCO,,[Na+].[OH-],,test
US20120238574A1,CC(C)(C)OC(=O)N1CCC(=Cc2ccc([N+](=O)[O-])c(Cl)c2)CC1>>CC(C)(C)OC(=O)N1CCC(Cc2ccc(N)c(Cl)c2)CC1,O=[Pt]=O,CCO,,,,test
US20150239837A1,CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)NCc1cccc(Cl)c1F.Cl>>Cl.O=C(NCc1cccc(Cl)c1F)[C@@H]1C[C@@H](F)CN1,,C1COCCO1,Cl,,,test
US20140024656A1,CCOC(=O)c1ccccc1.NN>>NNC(=O)c1ccccc1,,CCO,,O,,test
US20040024039A1,Cc1c(O[Si](C)(C)C(C)(C)C)ccc2cc(Br)ccc12.O=Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>Cc1c(O[Si](C)(C)C(C)(C)C)ccc2cc(C(O)c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)ccc12,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US20090156600A1,CCC(=O)C(Cc1ccc(Cl)cc1F)C(=O)OC.COC(=O)COc1ccc(Cl)c(N)c1>>CCc1[nH]c2c(Cl)ccc(OCC(=O)OC)c2c(=O)c1Cc1ccc(Cl)cc1F,,O,,C1COCCO1,,test
US20150141401A1,CC(C)(C)OC(=O)[C@@H]1CC[C@@H](NOCc2ccccc2)CN1.O=C(Cl)OC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1,CN(C)c1ccncc1,CC#N,,CCN(CC)CC,,test
US20070027126A1,CCS(=O)(=O)Cl.Cn1c(C#N)ccc1-c1ccc(N)cc1>>CCS(=O)(=O)Nc1ccc(-c2ccc(C#N)n2C)cc1,,CCOC(C)=O,c1ccncc1,O,,test
US20080039454A1,COC(=O)c1cc(Cl)ccc1C1=CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)c1cc(Cl)ccc1C1CCN(C(=O)OC(C)(C)C)CC1,O=[Pt]=O,CC(=O)O,CCO,[H][H],,test
US03977860,NCC(=O)O.O=P(O)(O)CCl>>O=C(O)CNCP(=O)(O)O,,O,,[Na+].[OH-],,test
US20160039834A1,CC#Cc1nc(-c2cccc(OCC(O)CN(C)C(=O)OC(C)(C)C)c2)nc(NC2CCOCC2)c1C.C[Si](C)(C)CN=[N+]=[N-]>>Cc1nnn(C[Si](C)(C)C)c1-c1nc(-c2cccc(OCC(O)CN(C)C(=O)OC(C)(C)C)c2)nc(NC2CCOCC2)c1C,,Cc1ccccc1,,,,test
US20150210688A1,COCc1nc(C2CC2)c(-c2cc(C(=O)OC)ccc2C)[nH]1>>COCc1nc(C2CC2)c(-c2cc(C(=O)O)ccc2C)[nH]1,,CO,O,Cl,[Na+].[OH-],test
US07923450B2,COc1cc(NC(N)=S)ccc1-n1cnc(C)c1.O=C1C(Br)CCCC1c1ccc(OC(F)(F)F)cc1>>COc1cc(Nc2nc3c(s2)CCCC3c2ccc(OC(F)(F)F)cc2)ccc1-n1cnc(C)c1,,CCO,,,,test
US20090075979A1,C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1cc(C(F)(F)F)ccc1C=O>>C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1cc(C(F)(F)F)ccc1CO,,CO,,[BH4-].[Na+],,test
US20030144507A1,CC(=O)NCCc1cccc(N)c1.CCOC(=O)Cl>>CCOC(=O)Nc1cccc(CCNC(C)=O)c1,,c1ccncc1,,O,,test
US05747498,C#Cc1cccc(N)c1.CC(C)Oc1cc2nc[nH]c(=O)c2cc1OC(C)C.ClC(Cl)(Cl)Cl>>C#Cc1cccc(Nc2ncnc3cc(OC(C)C)c(OC(C)C)cc23)c1.Cl,,CC(C)O,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20050261245A1,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21.CS(=O)(=O)c1ccc(/C(COC(=O)OCCCCBr)=C(/CO)c2ccccc2)cc1>>CS(=O)(=O)c1ccc(/C(COC(=O)OCCCCBr)=C(/C(=O)O)c2ccccc2)cc1,,ClCCl,,,,test
US20070197604A1,CC1CCCCN1.Cc1oc(-c2ccc(Br)cc2)nc1CCOS(C)(=O)=O>>Cc1oc(-c2ccc(Br)cc2)nc1CCN1CCCCC1C,,C1CCOC1,,,,test
US20130079321A1,C=C1C[C@@H](NC(=O)OC(C)(C)C)CCN(c2c([N+](=O)[O-])cnn2C)C1.O=C(OO)c1cccc(Cl)c1>>Cn1ncc([N+](=O)[O-])c1N1CC[C@H](NC(=O)OC(C)(C)C)CC2(CO2)C1,,ClCCl,,,,test
US20070197619A1,CCN(Cc1nc(CC(=O)Nc2ccccc2N)cn1-c1ccc(Cl)cc1)c1ccc(F)cc1.CCOCC>>COc1ccccc1-c1nc(Cc2nc3ccccc3[nH]2)cn1-c1ccc(Cl)cc1,,CC(=O)O,CCOCC,Cl,[Na+].[OH-],test
US20030149027A1,CC(C)(C(=O)O)c1ccc([N+](=O)[O-])cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(N)c1ccc([N+](=O)[O-])cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20100152183A1,COC(=O)c1ccc(F)cc1Br.OB(O)/C=C/c1ccccc1>>COC(=O)c1ccc(F)cc1CCc1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20120295885A1,CC(=O)OCc1c(B2OC(C)(C)C(C)(C)O2)cccc1N1C(=O)c2ccc(C(C)(C)C)cc2CN1C.Cn1cc(Br)cc1C(N)=O>>CC(=O)OCc1c(-c2cc(C(N)=O)n(C)c2)cccc1N1C(=O)c2ccc(C(C)(C)C)cc2CN1C,,C1COCCO1,O,CC(C)c1cc(C(C)C)c(-c2ccccc2P(C2CCCCC2)C2CCCCC2)c(C(C)C)c1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US05030654,CC(=O)OC(C)=O.CC(C)(C)OC(=O)C(CCCCN)CC1(C(=O)N[C@H]2CC[C@@H](C(=O)O)CC2)CCCC1>>CC(=O)NCCCCC(CC1(C(=O)N[C@H]2CC[C@@H](C(=O)O)CC2)CCCC1)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,CO,test
US20160046624A1,CC(C)Oc1cnc2c(c1)c(=O)n(CCCOC1CCCCO1)c(=O)n2C.O=Cc1ccccc1>>CC(C)Oc1cnc2c(c1C(O)c1ccccc1)c(=O)n(CCCOC1CCCCO1)c(=O)n2C,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20120071536A1,CC1(C)CO1.O=C(NC(c1ccccc1)C12CC(CN1)C2)c1c(Cl)ccc(C(F)(F)F)c1Cl>>CC(C)(O)CN1CC2CC1(C(NC(=O)c1c(Cl)ccc(C(F)(F)F)c1Cl)c1ccccc1)C2,,CCO,,,,test
US20080004289A1,C[C@@H]1CNCCN1.FC(F)(F)c1cccc(C(Cl)c2ccccc2)c1>>C[C@@H]1CN(C(c2ccccc2)c2cccc(C(F)(F)F)c2)CCN1,,CC#N,,,,test
US20070167457A1,COC(=O)N1CCN(C(=O)OC(C)(C)C)C(CCOc2ccccc2)C1>>COC(=O)N1CCNC(CCOc2ccccc2)C1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20080300276A1,Clc1ccc(C=C2CCNCC2)cc1.O=C(O)c1nc2ccc(O)cc2[nH]1>>O=C(c1nc2ccc(O)cc2[nH]1)N1CCC(=Cc2ccc(Cl)cc2)CC1,,CC(C)O,,Cl,,test
US20130131016A1,C=C(Br)C(F)(F)F.Cc1c(Cl)cc(B2OC(C)(C)C(C)(C)O2)cc1Cl>>C=C(c1cc(Cl)c(C)c(Cl)c1)C(F)(F)F,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US05539112,C=CCOC(=O)Cl.Nc1ccc(-c2cc(=O)c3c(N)c(F)c(CO)c(F)c3o2)cc1F>>C=CCOC(=O)Nc1ccc(-c2cc(=O)c3c(N)c(F)c(CO)c(F)c3o2)cc1F,,c1ccncc1,,O,,test
US20130150325A1,CN.Cc1cc(/C(F)=C/c2ccc(OC(F)(F)F)cc2)nn1Cc1ccc(Cl)nc1>>CNc1ccc(Cn2nc(/C(F)=C/c3ccc(OC(F)(F)F)cc3)cc2C)cn1,,CCO,,,,test
US20080032995A1,CC(C)(C)OP(=O)(Oc1ccc(-c2coc3cc(OCc4coc(-c5cc(F)cc(C(F)(F)F)c5)n4)ccc3c2=O)cc1)OC(C)(C)C>>O=c1c(-c2ccc(OP(=O)(O)O)cc2)coc2cc(OCc3coc(-c4cc(F)cc(C(F)(F)F)c4)n3)ccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130131039A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.CN1CCC(c2ccc(-c3cc4nccn4c(Cl)n3)cc2)CC1>>CN1CCC(c2ccc(-c3cc4nccn4c(-c4cn[nH]c4)n3)cc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20130059850A1,Nc1ncccc1C#C[C@@H]1CC[C@@H](O)CC1>>O[C@@H]1CC[C@@H](c2cc3cccnc3[nH]2)CC1,,CCO,,,,test
US20050004014A1,CCCCC1(OC)CCN(C(=O)OC(C)(C)C)CC1.O=C(O)C(F)(F)F>>CCCCC1(OC)CCNCC1.O=C(O)C(F)(F)F,,ClCCl,,COc1ccccc1,,test
US20110082156A1,CC(C)(C)OC(=O)NCCN.Cc1cnc(C(=O)O)c[n+]1[O-]>>Cc1cnc(C(=O)NCCNC(=O)OC(C)(C)C)c[n+]1[O-],,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070032478A1,COc1ccc(N)cc1O.O=C1Nc2cc(C(=O)c3ccc(NC(=O)c4cccs4)cc3)ccc2C1=CO>>COc1ccc(NC=C2C(=O)Nc3cc(C(=O)c4ccc(NC(=O)c5cccs5)cc4)ccc32)cc1O,,C1CCOC1,,,,test
US20020165235A1,COC(=O)CBr.Oc1ccc(-c2ccccc2)cc1>>COC(=O)COc1ccc(-c2ccccc2)cc1,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05510326,C=C(C)CC(C)(CO)C1CC=C(C)C1(C)C>>CC1=CCC(C2(C)COC(C)(C)C2)C1(C)C,,CCCCCCC,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20140038919A1,COC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(Cc3ccc(OC)cc3)S(C)(=O)=O)c(OC(C)C)cc12>>COc1ccc(CN(c2cc3oc(-c4ccc(F)cc4)c(CO)c3cc2OC(C)C)S(C)(=O)=O)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20010011135A1,Nc1ccc(Br)c(C(F)(F)F)c1.O=C(Cl)OC(Cl)(Cl)Cl>>O=C=Nc1ccc(Br)c(C(F)(F)F)c1,,Cc1ccccc1,,Cl,,test
US05438052,Cc1cc(SCC2=C(C(=O)O)N3C(=O)[C@@H](NC(=O)C(=O)c4csc(N)n4)[C@H]3SC2)n2nc(C(=O)NO)nc2n1.NOCc1cc(Cl)c2c(c1Cl)OC(c1ccccc1)(c1ccccc1)O2>>Cc1cc(SCC2=C(C(=O)O)N3C(=O)[C@@H](NC(=O)/C(=N\OCc4cc(Cl)c5c(c4Cl)OC(c4ccccc4)(c4ccccc4)O5)c4csc(N)n4)[C@H]3SC2)n2nc(C(=O)NO)nc2n1,,CC(=O)N(C)C,,,,test
US04168385,COC(=O)C(Br)c1ccc(Oc2ccccc2)cc1.Sc1ccc(Cl)cc1>>COC(=O)C(Sc1ccc(Cl)cc1)c1ccc(Oc2ccccc2)cc1,,CO,,,,test
US04092311,CCOC(=O)Cl.NNc1ccc(-c2ccc(Cl)cc2)nn1>>CCOC(=O)NNc1ccc(-c2ccc(Cl)cc2)nn1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20050054627A1,CC(C)(C)OC(=O)N1C(=O)[C@@H]2C[C@H]1CC[C@@H]2NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N1C(=O)[C@@H]2C[C@H]1CC[C@@H]2N,[Pd],CO,,,,test
US05246948,ClCCCSc1ccncc1.O=c1[nH]c(=O)c2ccccc2[nH]1>>O=c1[nH]c2ccccc2c(=O)n1CCCSc1ccncc1,,CN(C)C=O,,C1CCC2=NCCCN2CC1,O,test
US20130023566A1,CCO.CCOC(OCC)OCC.O=Cc1ccccc1-c1noc2cc(Br)ccc12>>CCOC(OCC)c1ccccc1-c1noc2cc(Br)ccc12,Cc1ccc(S(=O)(=O)O)cc1,CCO,,,,test
US20060235033A1,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.Cc1ccc([C@H](C)N)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)N[C@@H](C)c4ccc(C)cc4)cc3)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20100137299A1,Cc1ccc(S(=O)(=O)OC[C@H]2COCCO2)cc1.O=C1Nc2ccccc2C12COc1cc3c(cc12)OCO3>>O=C1N(C[C@H]2COCCO2)c2ccccc2C12COc1cc3c(cc12)OCO3,,CN(C)C=O,,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US20100310466A1,CC(=O)c1cccc(-c2ccccc2)c1O.COC(=O)C1CCOCC1>>O=C(CC(=O)C1CCOCC1)c1cccc(-c2ccccc2)c1O,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20040044015A1,CN1CCN(CCCO)CC1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCCCN2CCN(C)CC2)cc1,,ClCCl,,CCN(CC)CC,,test
US20100266504A1,C=C1CCN(Cc2ccccc2)Cc2ccc(N3CCOCC3)nc21>>CC1CCNCc2ccc(N3CCOCC3)nc21,[Pd],CO,,,,test
US20160096827A1,O=CC1COC1.O=[N+]([O-])c1ccc(N2CCNCC2)cc1>>O=[N+]([O-])c1ccc(N2CCN(CC3COC3)CC2)cc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US06174884B1,CCCCCCC(C)NN.CCOC(C)=C(C#N)C#N.OO>>CCCCCCC(C)n1nc(C)c(C(N)=O)c1N,,CCO,CO,N,,test
US20070078135A1,O=C1c2ccccc2C(=O)N1C1CCN(c2cnc(-c3ccc(C(F)(F)F)cn3)c(-c3ccncc3Cl)n2)CC1>>NC1CCN(c2cnc(-c3ccc(C(F)(F)F)cn3)c(-c3ccncc3Cl)n2)CC1,,CCO,,NN,,test
US05605907,CNC(=S)C1(c2ccc3nc(C(F)(F)F)cn3c2)CCCCC1=O>>CNC(=S)C1(c2ccc3nc(C(F)(F)F)cn3c2)CCCCC1O,,CO,,O,[BH4-].[Na+],test
US20060106081A1,BrCc1ccccc1.CCCc1nc2cc(NS(=O)(=O)c3ccc(F)cc3)ccc2n1CC(=O)OC(C)(C)C>>CCCc1nc2cc(N(Cc3ccccc3)S(=O)(=O)c3ccc(F)cc3)ccc2n1CC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060205718A1,BrC1CC1.CCOc1cc(C=O)ccc1O>>CCOc1cccc(C=O)c1OC1CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080269170A1,O=S(=O)(c1ccc(Nc2nccc(Nc3ccc(F)cc3)n2)cc1)N(CCN1CCCC1)C1CCC2(CC1)OCCO2>>O=C1CCC(N(CCN2CCCC2)S(=O)(=O)c2ccc(Nc3nccc(Nc4ccc(F)cc4)n3)cc2)CC1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20040152742A1,O=C(O)/C=C/c1ccc(C(F)(F)F)cc1Cl>>O=C(O)CCc1ccc(C(F)(F)F)cc1Cl,[Ni],CO,,,,test
US20100331320A1,C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O.O=c1cc(I)ccn1CCO>>C[C@@H](c1ccc(-c2ccn(CCO)c(=O)c2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150336905A1,Clc1cc(Br)ccc1C1(C2CC2)CO1.c1nc[nH]n1>>OC(Cn1cncn1)(c1ccc(Br)cc1Cl)C1CC1,,CN1CCCC1=O,,[Na+].[OH-],[Cl-].[NH4+],test
US04885301,CCCOc1ccccc1-c1nc(N)c(N)c(=O)[nH]1.N=CN>>CCCOc1ccccc1C1=NC(=O)C2=NC=NC2=N1,,CCO,,CC(=O)O,CC(=O)[O-].[Na+],test
US20120269804A1,CCS(=O)(=O)Nc1cccc(Oc2cc(F)cc(Nc3ccc(I)cc3F)c2N)c1.NS(=O)(=O)Cl>>CCS(=O)(=O)Nc1cccc(Oc2cc(F)cc(Nc3ccc(I)cc3F)c2NS(N)(=O)=O)c1,,ClCCl,,CCN(C(C)C)C(C)C,[Cl-].[NH4+],test
US20110152273A1,COC(=O)c1c(C#N)cc(N[C@@H]2CCCC[C@@H]2N)nc1Nc1ccc2cn[nH]c2c1>>N[C@H]1CCCC[C@H]1Nc1cc2c(c(Nc3ccc4cn[nH]c4c3)n1)C(=O)NC2,[Pd],CO,,,,test
US20060111375A1,COc1cc2nccc(Cl)c2cc1OC.Cc1ccc(O)c(-c2cc(C)n(C)n2)n1>>COc1cc2nccc(Oc3ccc(C)nc3-c3cc(C)n(C)n3)c2cc1OC,CN(C)c1ccncc1,Clc1ccccc1Cl,,,,test
US20070099945A1,COc1ccc(F)cc1CC1(O)CCN(C(=O)OC(C)(C)C)CC1>>Fc1ccc2c(c1)CC1(CCNCC1)O2,,CC(=O)O,,Br,O,test
US20130345194A1,NC1COC1.NS(N)(=O)=O>>NS(=O)(=O)NC1COC1,,O,,,,test
US20020151547A1,CC(=O)Cl.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CC[C@H](N2CCNCC2)[C@H](c2ccccc2)C1>>CC(=O)N1CCN([C@H]2CCN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)C[C@H]2c2ccccc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20030032671A1,CCOC(=O)CN(CCc1ccc(SC(C)(C)C(=O)OC(C)(C)C)cc1)Cc1ccco1>>CC(C)(C)OC(=O)C(C)(C)Sc1ccc(CCN(CC(=O)O)Cc2ccco2)cc1,,CCO,,[Na+].[OH-],,test
US20110275838A1,CCCCCCCCCCCC/C(C(=O)OC)=C(/C(=O)OC)C([Se]c1ccccc1)C(=O)OC.OO>>CCCCCCCCCCCCC(O)(C(=O)OC)/C(=C/C(=O)OC)C(=O)OC,,ClCCl,,c1ccncc1,,test
US03966744,CC(N)Cc1ccccc1>>CC(N)Cc1ccccc1,,ClCCl,,O=S(=O)(O)O,[Na+].[OH-],test
US20140275179A1,CCOC(=O)c1c(-c2ccc(CC)cc2)nsc1C(F)(F)F>>CCc1ccc(-c2nsc(C(F)(F)F)c2CO)cc1,,Cc1ccccc1,,CC(C)C[AlH]CC(C)C,,test
US20100249425A1,CCOP(=O)(CCCN1C(=O)c2ccccc2C1=O)OCC>>CCOP(=O)(CCCN)OCC,,CCO,,NN,O,test
US20130217699A1,COC(=O)c1sc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2c1CCCC2>>O=C(O)c1sc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2c1CCCC2,,CO,O,[Li]O,,test
US20090156610A1,CC(C)(C)OC(=O)N1CC[C@H](OS(C)(=O)=O)C1.O=Cc1cc(I)ccc1O>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(I)cc2C=O)C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100144700A1,CC(C)(C)OC(=O)N1CC2CNCC1C2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CC2CC1CN(C(=O)C(F)(F)F)C2,,ClCCl,,CCN(CC)CC,,test
US20140080704A1,C1CCOC1.CC1=CC2(CC(C)(C)C1=O)OC(C)C(C)O2>>C#CC1(O)C(C)=CC2(CC1(C)C)OC(C)C(C)O2,,O,,,,test
US04309541,COc1cc2nc(Cl)nc(N)c2cc1OC.O=C1c2ccccc2CN1C1CCNCC1>>COc1cc2nc(N3CCC(N4Cc5ccccc5C4=O)CC3)nc(N)c2cc1OC.Cl,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20060241111A1,CCCN(N=C(c1ccccc1)c1ccccc1)C(=O)Nc1ccc(N2CCOCC2=O)cc1>>CCCN(N)C(=O)Nc1ccc(N2CCOCC2=O)cc1,,CCO,O,Cl,,test
US20110172230A1,O=C(c1cccc(OCCC2CCCCC2)c1)N1CCNCC1.O=C(n1ccnc1)n1ccnc1.c1ccc2[nH]ccc2c1>>O=C(c1cccc(OCCC2CCCCC2)c1)N1CCN(C(=O)n2ccc3ccccc32)CC1,CN(C)c1ccncc1,CC#N,CN(C)C=O,Cl,O,test
US05932599,CN.Cc1nc(Cl)c(N)c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)n1>>CNc1cc(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(NC)n1,,CCO,,CCN(CC)CC,Cl,test
US20140206663A1,CCOC(=O)[C@@H](C)N1C(=S)COc2ccc(Br)cc21.NN>>CC1C(=O)NN=C2COc3ccc(Br)cc3N21,,CCO,,O,,test
US08921499B2,CC(C)(Br)C(=O)Br.CCCCCCCCCCCCCCC1(CCCCCCCCCCCCCC)c2ccccc2-c2ccccc21>>CCCCCCCCCCCCCCC1(CCCCCCCCCCCCCC)c2ccccc2-c2cc3c(cc21)C(=O)C(C)C3,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100113504A1,COC(=O)CCCCCC(OCc1ccc(OC)cc1)C(=O)Nc1ccccc1>>COC(=O)CCCCC[C@@H](OCc1ccc(OC)cc1)C(=O)Nc1ccccc1,,ClC(Cl)Cl,,CCOCC,,test
US20160264552A1,CC(C)(C)OC(=O)N1CC(Nc2ncc(Cl)c(-c3c[nH]c4ccccc34)n2)CC(C(=O)O)C1>>O=C(O)C1CNCC(Nc2ncc(Cl)c(-c3c[nH]c4ccccc34)n2)C1,,ClCCl,,CCOC(C)=O,Cl,test
US20040106604A1,Cl[Mg]CCc1ccccc1.O=CCOCc1ccccc1>>OC(CCc1ccccc1)COCc1ccccc1,,C1CCOC1,,Cl,,test
US05756538,COS(=O)(=O)OC.O=c1cc(-c2ccccc2)oc2cc(O)cc(O)c12>>COc1cc(O)c2c(=O)cc(-c3ccccc3)oc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160022619A1,Cc1cc(N)no1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>Cc1cc(NC(=O)Oc2ccc([N+](=O)[O-])cc2)no1,,C1CCOC1,,,,test
US20110021351A1,COC(=O)CC(=O)OC.COC(=O)c1nccnc1N>>COC(=O)c1c(O)c2nccnc2[nH]c1=O,,CO,,C[O-].[Na+],,test
US20050203296A1,FC(F)(F)c1ccc(CC[C@H]2CN(Cc3ccccc3)CCN2Cc2ccccc2)cc1>>FC(F)(F)c1ccc(CC[C@H]2CNCCN2)cc1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20140142083A1,CCN(c1cc(C(F)(F)F)cc(C(=O)OC)c1C)C1CCN(C(C)C)CC1>>CCN(c1cc(C(F)(F)F)cc(C(=O)O)c1C)C1CCN(C(C)C)CC1,,CO,,Cl,[Na+].[OH-],test
US20100160369A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccc(CN=[N+]=[N-])cc1Cl>>COC(=O)c1ccc(CNC(=O)OC(C)(C)C)cc1Cl,[Pd],CCO,,,,test
US20120214803A1,COc1cc(NS(=O)(=O)c2ccccc2[N+](=O)[O-])c2ncccc2c1>>COc1cc(NS(=O)(=O)c2ccccc2N)c2ncccc2c1,Cl,,,Cl[Sn]Cl,,test
US20120149718A1,COC(=O)Cc1ccc(S(C)(=O)=O)cc1.Fc1ccc(CBr)cc1>>COC(=O)C(Cc1ccc(F)cc1)c1ccc(S(C)(=O)=O)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20040106606A1,CC(C)c1ccc([N+](=O)[O-])c(NC(=O)C(F)(F)F)c1>>CC(C)c1ccc([N+](=O)[O-])c(N)c1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20150165063A1,COc1cc2c(cc1OCCCCCC(=O)N1C[C@@H](CCl)c3c1cc(OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN4C(=O)C=CC4=O)C(C)C)cc1)c1ccccc31)N(C(=O)OC(C)(C)C)[C@@H](O)[C@@H]1CCCN1C2=O>>COc1cc2c(cc1OCCCCCC(=O)N1C[C@@H](CCl)c3c1cc(OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN4C(=O)C=CC4=O)C(C)C)cc1)c1ccccc31)N=C[C@@H]1CCCN1C2=O,,ClCCl,O=C(O)C(F)(F)F,O,O=C([O-])O.[Na+],test
US06495551B1,CC(C)(C)[Si](C)(C)OCc1cn(-c2ccc(N3C[C@H](COS(C)(=O)=O)OC3=O)cc2F)cn1.[N-]=[N+]=[N-]>>CC(C)(C)[Si](C)(C)OCc1cn(-c2ccc(N3C[C@H](CN=[N+]=[N-])OC3=O)cc2F)cn1,,CN(C)C=O,O,O=C([O-])O.[Na+],,test
US20130231328A1,CN(C(=O)OC(C)(C)C)C1CCC(Oc2ncnc3sc4c(c23)[C@@H](CC=O)CC4)CC1.CO.COC(OC)OC>>COC(C[C@H]1CCc2sc3ncnc(OC4CCC(N(C)C(=O)OC(C)(C)C)CC4)c3c21)OC,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20050182052A1,NC[C@H]1CN(Cc2ccccc2)C[C@H]1F.O=Cc1ccccc1>>F[C@@H]1CN(Cc2ccccc2)C[C@@H]1CNCc1ccccc1,,CO,,Cl,[Na+].[OH-],test
US05051423,c1ccc(CNCCOc2ccc(-n3ccnc3)cc2)cc1.c1ccc(OCC2CO2)cc1>>OC(COc1ccccc1)CN(CCOc1ccc(-n2ccnc2)cc1)Cc1ccccc1,,CO,,,,test
US20080039517A1,CC(C)(C)OC(=O)C[C@@H](CN=[N+]=[N-])Nc1ccc(C#N)c(Cl)c1>>CC(C)(C)OC(=O)C[C@@H](CN)Nc1ccc(C#N)c(Cl)c1,O=[Pt]=O,CCO,,,,test
US20060135773A1,O=C(Cl)OCc1ccccc1.O=P(O)(O)C(F)(F)c1ccc(CNCc2ccc(C(F)(F)P(=O)(O)O)cc2)cc1>>O=C(OCc1ccccc1)N(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)Cc1ccc(C(F)(F)P(=O)(O)O)cc1,CN(C)c1ccncc1,ClCCl,,,,test
US20110193073A1,COCCOCCN(CC(=O)OCc1ccccc1)C(=O)OC(C)(C)C>>COCCOCCNCC(=O)OCc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],test
US20150051197A1,COC(=O)C1(c2ccc(OC)cc2)CCC(=O)CC1.NCCS(N)(=O)=O>>COC(=O)C1(c2ccc(OC)cc2)CCC(NCCS(N)(=O)=O)CC1,,CC#N,CC(=O)O,[Na+].[OH-],,test
US20130267499A1,CN.COc1ccc(Cn2cc(C(=O)N(C)OC)c(Cl)n2)cc1>>CNc1nn(Cc2ccc(OC)cc2)cc1C(=O)N(C)OC,,CCOC(C)=O,CN1CCCC1=O,O,,test
US20040235822A1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(C(O)c4ccccn4)c(Cl)c2)CCN3C(=O)C(F)(F)F)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(C(O)c4cccc[n+]4[O-])c(Cl)c2)CCN3C(=O)C(F)(F)F)cc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20140121377A1,CC(=O)c1ccc(Br)nc1.c1c[nH]cn1>>CC(=O)c1ccc(-n2ccnc2)nc1,,CN(C)C=O,O,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20140371165A1,COc1ccc(-c2cc(C(O)c3ccccn3)c3ccccc3n2)cc1>>COc1ccc(-c2cc(C(O)C3CCCCN3)c3ccccc3n2)cc1,O=[Pt]=O,CO,,Cl,,test
US20100273764A1,COc1ccc(CN)cc1.Cc1nc(Cl)nc(Cl)n1>>COc1ccc(CNc2nc(C)nc(Cl)n2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20150291563A1,COC(=O)C1=NN(c2ccc(F)cc2F)C(c2ccc(Br)s2)C1>>OCC1=NN(c2ccc(F)cc2F)C(c2ccc(Br)s2)C1,,CO,,[BH4-].[Na+],,test
US20070099880A1,CC(=O)O[C@H]1CC[C@@]2(C=O)C(=CC[C@@H]3[C@@H]2CC[C@]2(C)[C@@H](OC(C)=O)CC[C@@H]32)C1.C[Mg]I>>CC(O)[C@]12CC[C@H](O)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12,,C1CCOC1,,,,test
US06369272B1,C1CCC2=NCCCN2CC1.CC(C)(C)OC(=O)N[C@@H](CS)C(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)OCCNC(=O)OCc2ccccc2)cc1.Cc1ccccc1>>CC(=N)NCCN[C@@H](CCS)C(=O)O,,Cc1ccccc1,,,,test
US20150018422A1,CC#C[Mg]Br.CC1(C)OC(=O)C(=Cc2cccc(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)c2)C(=O)O1>>CC#CC(c1cccc(CO[Si](C)(C)C(C)(C)C)c1)C1C(=O)OC(C)(C)OC1=O,,C1CCOC1,,[Cl-].[NH4+],,test
US20070219229A1,CNc1cccc(Cl)c1.COC(=O)c1cnc(Cl)c2ccn(C)c12>>COC(=O)c1cnc(N(C)c2cccc(Cl)c2)c2ccn(C)c12,,C1COCCO1,,CS(=O)(=O)O,,test
US05721234,CC(=O)O.O=C(O)CCC1CCc2cc([N+](=O)[O-])ccc21>>CC(=O)Nc1ccc2c(c1)CCC2CCC(=O)O,[Ni],CC(=O)O,,CC(=O)OC(C)=O,,test
US20050107419A1,CCOC(=O)c1c(Cc2ccc(F)cc2F)nc2c(c1-c1ccc(C(=O)O)cc1)C(=O)N1CCC[C@@H]21.NN1CCc2ccccc21>>CCOC(=O)c1c(Cc2ccc(F)cc2F)nc2c(c1-c1ccc(C(=O)NN3CCc4ccccc43)cc1)C(=O)N1CCC[C@@H]21,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US05116863,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.OCCc1ccc2c(c1)C(O)c1ccccc1CO2>>OC1c2ccccc2COc2ccc(CCOC(c3ccccc3)(c3ccccc3)c3ccccc3)cc21,,c1ccncc1,,O,,test
US20040082590A1,CC(C)(C)OC(=O)N1CCN(c2ccccc2O)CC1.CC(CO)CNC(=O)OCc1ccccc1>>CC(COc1ccccc1N1CCN(C(=O)OC(C)(C)C)CC1)NC(=O)OCc1ccccc1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150141406A1,CC1(C)OB(c2ccc(S(N)(=O)=O)cc2)OC1(C)C.COc1nccc2c1c(OS(=O)(=O)C(F)(F)F)nn2C1CCCOC1>>COc1nccc2c1c(-c1ccc(S(N)(=O)=O)cc1)nn2C1CCCOC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US20140323464A1,CN1CCN(c2ccc(Nc3ncc(F)c(NC4CCCN(C(=O)CC#N)C4)n3)cn2)CC1.O=CC1CC1>>CN1CCN(c2ccc(Nc3ncc(F)c(NC4CCCN(C(=O)C(C#N)=CC5CC5)C4)n3)cn2)CC1,,CCO,,,,test
US20070167433A1,COCCCN1CCOc2ccc(COC3CNCC(O)C3c3ccc(OC4CCN(c5cccc(F)c5)C4)cc3)cc21.Cc1ccc(S(=O)(=O)Cl)cc1>>COCCCN1CCOc2ccc(COC3CN(S(=O)(=O)c4ccc(C)cc4)CC(O)C3c3ccc(OC4CCN(c5cccc(F)c5)C4)cc3)cc21,,CCOC(C)=O,,O=C([O-])[O-].[Na+].[Na+],,test
US04031257,CC(O)CCS.CCCCCCCCCC=O>>CCCCCCCCCC1OC(C)CCS1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20020107251A1,COC(=O)c1cccc(-n2c(=O)c(C)nc3cccnc32)c1.O=C1CCC(=O)N1Br>>COC(=O)c1cccc(-n2c(=O)c(CBr)nc3cccnc32)c1,,ClC(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US04824843,Cc1ccc(C)c(OCCCC(C)(C)C(=O)Cl)c1.Nc1cccc(C2=NCCCO2)c1>>Cc1ccc(C)c(OCCCC(C)(C)C(=O)Nc2cccc(C3=NCCCO3)c2)c1,,ClCCl,,CCN(CC)CC,,test
US20100076193A1,CCOC(=O)/C=C(/C)NCC1CN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1=NOC.CS(=O)(=O)O>>CO/N=C1\CN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1CN.CS(=O)(=O)O,,ClCCl,,CCO,,test
US20080269208A1,CCOC(=O)C(Br)C(=O)OCC.O=C(NC[C@H]1CCCN1)OCc1ccccc1>>CCOC(=O)C(C(=O)OCC)N1CCC[C@@H]1CNC(=O)OCc1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150166549A1,CCCc1oc(=O)c2ccccc2c1I.OB(O)c1ccccc1>>CCCc1oc(=O)c2ccccc2c1-c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160038486A1,COCCOCn1nccc1[C@H]1C[C@@H](O)CC[C@@H]1OC(=O)c1ccccc1>>COCCOCn1nccc1[C@H]1CC(=O)CC[C@@H]1OC(=O)c1ccccc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05004748,C#CCNCc1ccccc1.COC(=O)c1cc(C(=O)OC)c(Br)cn1>>COC(=O)c1cc(C(=O)OC)c(C#CCNCc2ccccc2)cn1,,ClCCl,,,,test
US04992474,C1=COCCC1.OCCCCCl>>ClCCCCOC1CCCCO1,Cl,,,,,test
US06218376B1,CCc1nc2c(s1)C=Cc1cc(C)ccc1C2c1c[nH]c(=O)[nH]c1=S.CI>>CCc1nc2c(s1)C=Cc1cc(C)ccc1C2c1c[nH]c(=O)nc1SC,,CCO,O,O=C([O-])O.[Na+],,test
US20020133007A1,CCOC(=O)/C=C(\N)C(F)(F)F.Cc1c(Cl)cc(F)c(NC(=O)Oc2ccccc2)c1[N+](=O)[O-]>>Cc1c(Cl)cc(F)c(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c1[N+](=O)[O-],,CN(C)C=O,O,C1CCC2=NCCCN2CC1,Cl,test
US06440968B1,COc1c2c(c(O)c3c1C(=O)c1c(cc(O)c(C)c1O)C3=O)-c1c(cc3c(c1O)C(=O)OC3O)CC2.NNc1ccccc1>>COc1c2c(c(O)c3c1C(=O)c1c(cc(O)c(C)c1O)C3=O)-c1c(cc3cnn(-c4ccccc4)c(=O)c3c1O)CC2,,CC(=O)O,,,,test
US04812462,CN(C(=O)N1Cc2ncn(Cc3ccccc3)c2C[C@H]1CO[Si](C)(C)C(C)(C)C)c1ccccc1.O=C1CCC(=O)N1Br>>CN(C(=O)N1Cc2nc(Br)n(Cc3ccccc3)c2C[C@H]1CO[Si](C)(C)C(C)(C)C)c1ccccc1,,ClCCl,,,,test
US20010056212A1,CCCCC=CC=COCC(O)CO>>CCCCCCCCOCC(O)CO,[Pd],,,,,test
US04638060,CC(C)(C)OC(=O)NC(C(=O)OCc1ccccc1)C1(O)CCCC1>>CC(C)(C)OC(=O)NC(C(=O)O)C1(O)CCCC1,[Pd],CCO,,[H][H],,test
US20040124399A1,CCCCCc1ccc(Br)cc1.CCCCOc1ccc2c(c1F)Cc1c-2ccc(B(O)O)c1F>>CCCCCc1ccc(-c2ccc3c(c2F)Cc2c-3ccc(OCCCC)c2F)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20050070549A1,CC(C)(C)OC(=O)N1CCC(NC(CO)Cc2ccc(Cl)cc2)CC1.O=C(c1ncc[nH]1)c1ncc[nH]1>>CC(C)(C)OC(=O)N1CCC(N2C(=O)OCC2Cc2ccc(Cl)cc2)CC1,,ClCCl,,CCN(CC)CC,,test
US04432971,CC(C)(C)OC(=O)ON=C(C#N)c1ccccc1.CNCC(=O)O>>CN(CC(=O)O)C(=O)OC(C)(C)C,,C1COCCO1,O,CCN(CC)CC,,test
US20040209921A1,CC(C)(c1ccc(F)cc1)c1cccnc1C=O.Cc1cnc(CNCc2ccc(C#N)cc2CO)c(C)c1>>Cc1cnc(CN(Cc2ccc(C(N)=O)cc2CO)Cc2ncccc2C(C)(C)c2ccc(F)cc2)c(C)c1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20080280876A1,CC(C)Oc1ccc(-c2noc(C3CCC(=O)C3)n2)cc1Cl.NCCC(=O)O>>CC(C)Oc1ccc(-c2noc(C3CCC(NCCC(=O)O)C3)n2)cc1Cl,,CO,ClCCCl,CC(=O)O,[BH3-]C#N.[Na+],test
US05476954,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)[C@H](O)[C@@H](N)c1ccc(C)cc1>>CCOC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c1ccc(C)cc1,,ClCCl,,O,O=C([O-])O.[Na+],test
US20160214978A1,CC(C)(C)OC(=O)Nc1ccc(F)cc1Nc1cc(Cl)nc(S(C)(=O)=O)n1>>CS(=O)(=O)c1nc(Cl)cc(Nc2cc(F)ccc2N)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060166997A1,CC(O)c1ccc(F)c(Br)c1>>CCc1ccc(F)c(Br)c1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20030083449A1,N#Cc1ccc(N)cc1.NC(N)=O.Nc1ccccc1>>N#Cc1ccc(N=NC2=CCC(=N)C=C2)cc1,,O,,,,test
US04585877,CCc1ccccc1N.Cl.O=N[O-]>>CCc1ccccc1NN.Cl,,Cl,O,Cl[Sn]Cl,,test
US20110028467A1,Nc1c(Cl)ccnc1O.O=C(Cl)CCl>>O=C1COc2nccc(Cl)c2N1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100076027A1,COC(=O)c1ccc(NC(=O)C(c2c3c(nn2-c2ccc(Cl)cc2)CCCC3)C2CCCCC2)c(C(F)(F)F)c1>>O=C(O)c1ccc(NC(=O)C(c2c3c(nn2-c2ccc(Cl)cc2)CCCC3)C2CCCCC2)c(C(F)(F)F)c1,,C1CCOC1,CO,[Li+].[OH-],,test
US20060270706A1,CC(C)(C)OC(=O)NCCO.CS(=O)(=O)OCCCCOS(C)(=O)=O>>CC(C)(C)OC(=O)NCCOS(C)(=O)=O,,ClCCl,,CCN(CC)CC,O,test
US20140045819A1,Nc1c(Cl)cccc1[N+](=O)[O-].[I-]>>O=[N+]([O-])c1cccc(Cl)c1I,,Cl,O,O=N[O-].[Na+],,test
US20120202834A1,COC(CC(OC)OC)OC.COc1ccc(NN)cc1>>COc1ccc(-n2cccn2)cc1,,CCO,,Cl,,test
US20140135327A1,C=C1CN(Cc2ccc(C(=O)Nc3ccccc3N)cc2)C(CC(=O)OC)c2ccccc21>>C=C1CN(Cc2ccc(C(=O)Nc3ccccc3N)cc2)C(CC(=O)O)c2ccccc21,,CCO,,[Na+].[OH-],,test
US20140356322A1,CC(=O)N[C@@H](C)C(=O)N1C[C@H](O)C[C@H]1C(=O)OCc1ccccc1>>CC(=O)N[C@@H](C)C(=O)N1C[C@H](O)C[C@H]1C(=O)O,[Pd],CCO,,[H][H],,test
US20080312270A1,CI.Cc1nc2cc([N+](=O)[O-])c(Oc3ccc(CC(=O)O)cc3Cl)cc2n1COCC[Si](C)(C)C>>COC(=O)Cc1ccc(Oc2cc3c(cc2[N+](=O)[O-])nc(C)n3COCC[Si](C)(C)C)c(Cl)c1,,CCOCC,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05025036,CCCc1cc(C(=O)OCC)ccc1O.COc1cccc(CCCCCCBr)c1OC>>CCCc1cc(C(=O)OCC)ccc1OCCCCCCc1cccc(OC)c1OC,,CC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20120270824A1,CC(=O)OC[C@H]1O[C@H](Oc2ccc(I)cc2Cl)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.Clc1cnc2[nH]ccc2c1>>CC(=O)OC[C@H]1O[C@H](Oc2ccc(-n3ccc4cc(Cl)cnc43)cc2Cl)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,[Cu]I,,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US05274143,CCCCCCCCCCC[C@H](CC(=O)OC)OC(=O)CBr>>CCCCCCCCCCC[C@@H]1CC(O)=CC(=O)O1,[Zn],CCOCC,,C[Si](C)(C)Cl,,test
US20060264415A1,O=C1c2ccccc2C(=O)N1CCSc1nnc(NS(=O)(=O)c2ccc(-c3ccccc3)cc2)s1>>NCCSc1nnc(NS(=O)(=O)c2ccc(-c3ccccc3)cc2)s1,,CO,,NN,O,test
US20060079533A1,CC(C)(C)OC(=O)N1CCC(c2ccc(COC(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)C(OCc2ccc3ccccc3c2)C1>>CC(C)(C)OC(=O)N1CCC(c2ccc(CO)cc2)C(OCc2ccc3ccccc3c2)C1,,CO,ClCCl,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20100267722A1,O=S(=O)(CCBr)c1ccccc1C(F)(F)F>>C=CS(=O)(=O)c1ccccc1C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20080306055A1,CNOC.COc1ncc(C(=O)O)cc1Cl>>COc1ncc(C(=O)N(C)OC)cc1Cl,,ClCCl,O=S(Cl)Cl,Cl,,test
US20160046596A1,CCc1nccc(C=O)c1O.Nc1ccc(F)c(Cl)c1>>CCc1nccc(C=Nc2ccc(F)c(Cl)c2)c1O,,CC#N,,,,test
US07109225B2,CCN(CC)CC.CCOC(=O)CN.O=C(Cl)c1ccccc1>>CCOC(=O)CNC(=O)C(C)(C)C,,ClCCl,,Cl,,test
US20050085465A1,C=CCN1CCN(CCCO)CC1.COc1cc2c(Cl)ncnc2cc1O>>C=CCN1CCN(CCCOc2cc3ncnc(Cl)c3cc2OC)CC1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05145840,COC(OC)N(C)C.Cc1cn([C@H]2C[C@@](O)(N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O>>Cc1cn([C@H]2C[C@@](O)(N=[N+]=[N-])[C@@H](CO)O2)c(=O)n(C)c1=O,,ClC(Cl)Cl,,,,test
US20080287468A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.O=C(N[C@@H]1CC[C@@H](O)c2ccc(F)cc21)C(F)(F)F>>CC(C)(C)[Si](O[C@@H]1CC[C@@H](NC(=O)C(F)(F)F)c2cc(F)ccc21)(c1ccccc1)c1ccccc1,,CN(C)C=O,,c1c[nH]cn1,,test
US06143779,COc1ccc(C=C2Oc3cc(O)ccc3C2=O)cc1OC.O=C(Cl)c1ccccc1>>COc1ccc(C=C2Oc3cc(OC(=O)c4ccccc4)ccc3C2=O)cc1OC,,c1ccncc1,,CCOC(C)=O,,test
US20080085890A1,C=CCN=Cc1ccc(Br)cc1.C=CC[Mg]Br>>C=CCNC(CC=C)c1ccc(Br)cc1,,C1CCOC1,,,,test
US20120184587A1,COc1c(C=O)cc(C(=O)O)cc1C1CCC1.NO>>COc1c(C#N)cc(C(=O)O)cc1C1CCC1,,O=CO,,Cl,,test
US20040176380A1,c1ccc(CN(Cc2ccccc2)[C@@H]2CC[C@@H](N3CCN(c4ccccc4)CC3)CC2)cc1>>N[C@@H]1CC[C@@H](N2CCN(c3ccccc3)CC2)CC1,[Pd],CO,,,,test
US20040087624A1,CCOc1c(C(=O)O)c(C(=O)O)c(OCC)c2ccccc12>>CCOc1c2c(c(OCC)c3ccccc13)C(=O)OC2=O,,ClC(Cl)Cl,,O=S(Cl)Cl,,test
US04721791,Cc1ccc(CN=[N+]=[N-])cc1C(Cl)=C(Cl)Cl.N#CCC(N)=O>>Cc1ccc(Cn2nnc(C(N)=O)c2N)cc1C(Cl)=C(Cl)Cl,,CCO,,[Na+].[OH-],,test
US20060116383A1,COC(=O)C[C@@H](N)c1ccccc1.O=[N+]([O-])c1ccc(Cl)c([N+](=O)[O-])c1>>COC(=O)C[C@@H](Nc1ccc([N+](=O)[O-])cc1[N+](=O)[O-])c1ccccc1,,CO,,CCN(CC)CC,,test
US20090275756A1,Cc1ccc([C@@H]2CC[C@@H]([C@@H]3CC[C@@H](C4CC(=O)O4)CC3)CC2)cc1>>C=C[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](c3ccc(C)cc3)CC2)CC1,,CCCCCCC,,,,test
US20150210697A1,CS(=O)(=O)Cl.N#Cc1cc(CO)c(Cl)c(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1>>CS(=O)(=O)OCc1cc(C#N)cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl,,C1CCOC1,,,,test
US05807859,CNC(=O)Nc1ccc2c(c1)C(C)(N)c1c-2[nH]c(=O)c2nccn12>>CNC(=O)Nc1ccc2c(c1)C(C)(N)c1c-2[nH]c(=O)c2nccn12,,CO,,CCN(CC)CC,Cl,test
US04064236,CCOC(=O)C(CCCCNC(=O)OCc1ccccc1)OC(=O)N(C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(C)=O.Cl>>CCOC(=O)C(CCCCN)OC(=O)N(C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(C)=O.Cl,[Pd],,,[H][H],,test
US20050256170A1,CCOC(=O)CCc1cccc(N)c1.O=C(O)c1ccc(-c2ccc(F)cc2)o1>>O=C(O)CCc1cccc(NC(=O)c2ccc(-c3ccc(F)cc3)o2)c1,,CCOC(C)=O,,,,test
US20100305096A1,CC(C)(O)C(=O)O.CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CNC3)n(C)c2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CN(C(=O)C(C)(C)O)C3)n(C)c2n1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160200695A1,Nc1cccc(F)c1.O=C(O)c1sc2ccccc2c1Cl>>O=C(Nc1cccc(F)c1)c1sc2ccccc2c1Cl,,CN(C)C=O,,O=C(Cl)C(=O)Cl,,test
US20140323435A1,COc1cnccc1-c1nc(NC[C@@H](N)Cc2ccccc2)c2c3c(sc2n1)CCCC3>>N[C@H](CNc1nc(-c2ccncc2O)nc2sc3c(c12)CCCC3)Cc1ccccc1,,ClCCl,,BrB(Br)Br,,test
US20030083385A1,CN=C=S.COc1ccc(Cl)cc1C(=O)NCCc1ccc(OC)c(S(N)(=O)=O)c1>>CNC(=S)NS(=O)(=O)c1cc(CCNC(=O)c2cc(Cl)ccc2OC)ccc1OC,,CN(C)C=O,,Cl,[H-].[Na+],test
US05202330,CCOC(=O)C1=C(C)NC(SCc2ccc(OC)cc2)=NC1c1cccc([N+](=O)[O-])c1.O=C(Cl)c1ccccc1>>CCOC(=O)C1=C(C)N=C(SCc2ccc(OC)cc2)N(C(=O)c2ccccc2)C1c1cccc([N+](=O)[O-])c1,,ClCCl,,c1ccncc1,,test
US20120225867A1,CCOC(=O)c1cc(-c2cn(Cc3ccccc3)cn2)n[nH]1>>O=C(O)c1cc(-c2cn(Cc3ccccc3)cn2)n[nH]1,,CO,,[Na+].[OH-],,test
US04918074,BrBr.COC(=O)C1=C(C)Nc2ncnn2C1c1cccs1>>COC(=O)C1=C(CBr)Nc2ncnn2C1c1cccs1,,CC(=O)O,,O,,test
US20050256159A1,CN(C)C=O.Cc1ccc(C(=O)N2CCC(C(=O)c3ccc(F)cc3)CC2)cc1>>Cc1ccc(C(=O)N2CCC(C(=O)c3ccc(N(C)C)cc3)CC2)cc1,,CN(C)C=O,,C1COCCN1,,test
US20100035835A1,C[C@@H](COC(=O)C(C)(C)C)NC(=O)OC(C)(C)C.Cl>>C[C@H](N)COC(=O)C(C)(C)C.Cl,,CCOC(C)=O,,C1COCCO1,,test
US20140080821A1,Cn1c(CBr)c(C(=O)c2ccccc2)c(=O)n(C)c1=O.Nc1ccccc1N>>Cn1c(=O)c2c(-c3ccccc3)n(-c3ccccc3N)cc2n(C)c1=O,,CCO,,,,test
US20060148820A1,O=S(=O)(c1ccccc1)c1ccc2c(c1)OCCC2O.O=S(Cl)Cl>>O=S(=O)(c1ccccc1)c1ccc2c(c1)OCCC2Cl,,Cc1ccccc1,,,,test
US20110245232A1,OCc1cnccc1Oc1ccccc1>>O=Cc1cnccc1Oc1ccccc1,O=[Mn]=O,C1CCOC1,,,,test
US20130137661A1,CC(C)(C)OC(=O)N[C@@H](Cn1c(=O)c(NC(=O)CCCCl)cn(Cc2c(F)cccc2F)c1=O)c1ccccc1>>CC(C)(C)OC(=O)N[C@@H](Cn1c(=O)c(N2CCCC2=O)cn(Cc2c(F)cccc2F)c1=O)c1ccccc1,,CN(C)C=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20100099755A1,CC(=O)c1ccc(O)cc1O.COC(Cl)Cl>>COCOc1ccc(C(C)=O)c(O)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160052884A1,CC(C(=O)O)n1cc(Cl)c(-c2cc(Cl)ccc2C#N)cc1=O.Nc1ccc(C(=O)O)c(F)c1>>CC(C(=O)Nc1ccc(C(=O)O)c(F)c1)n1cc(Cl)c(-c2cc(Cl)ccc2C#N)cc1=O,,CC(Cl)Cl,,CC(C)N=C=NC(C)C,,test
US20100130471A1,CCc1cccc(-c2c(Cl)cccc2[C@H](O)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1.COC(=O)N1CCOS1(=O)=O>>CCc1cccc(-c2c(Cl)cccc2[C@H](OCCNC(=O)OC)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1,,CN(C)C=O,,,,test
US20030069239A1,COc1cccc(N)c1.Clc1nc(-c2ccccc2)nc2ccccc12>>COc1ccc(Nc2nc(-c3ccccc3)nc3ccccc23)cc1,,CCCCCC,CCOC(C)=O,C1CCOC1,[H-].[Na+],test
US20150105373A1,COC(=O)C(C)(C)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>CC(C)(CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)C(=O)O,,C1CCOC1,,Cl,[Na+].[OH-],test
US20110152321A1,COc1ccc(NC(=O)c2ccc3[nH]c(CCCN(C)C(=O)OC(C)(C)C)cc3c2)cc1OC>>CNCCCc1cc2cc(C(=O)Nc3ccc(OC)c(OC)c3)ccc2[nH]1,,CCOCC,,Cl,ClCCl,test
US05646173,CC(C)CBr.CC=CCC1Cc2ccc(O)cc2C1=O>>CC=CCC1Cc2ccc(OCC(C)C)cc2C1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110021537A1,O=C(NCC(=O)N1CCNCC1)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OCCC(F)(F)F>>O=C(NCC(=O)N1CCN(C(=O)OCCC(F)(F)F)CC1)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150322082A1,Cc1ccc(-n2ccc3cc(N4CCOc5ncnc(Cl)c5C4=O)cc(C4CC4)c32)cn1.N>>Cc1ccc(-n2ccc3cc(N4CCOc5ncnc(N)c5C4=O)cc(C4CC4)c32)cn1,,C1COCCO1,,,,test
US20100179147A1,COc1cc(/C=N/c2ccc(C)cc2NC(=O)c2ccccc2)cc(OC)c1OC>>COc1cc(CNc2ccc(C)cc2NC(=O)c2ccccc2)cc(OC)c1OC,,CO,,[BH4-].[Na+],,test
US20140088078A1,CCBr.Fc1cccc(C[C@@H]2CCNC2)c1>>CCN1CC[C@@H](Cc2cccc(F)c2)C1,,CC#N,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20160009726A1,C=C(C)c1cnn2ccc(C(=O)Nc3cnccc3[C@H]3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](C)C3)nc12>>CC(C)c1cnn2ccc(C(=O)Nc3cnccc3[C@H]3C[C@@H](N)C[C@@H](C)C3)nc12,[Pd],,,,,test
US20080032971A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCNCc1ccc([N+](=O)[O-])cc1>>CCN(Cc1ccc([N+](=O)[O-])cc1)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US05532255,CCOC(=O)CCN1CCN(CC2CN(c3ccc(C(=N)N)cc3)C(=O)O2)CC1>>N=C(N)c1ccc(N2CC(CN3CCN(CCC(=O)O)CC3)OC2=O)cc1,,O,,C1COCCO1,[Na+].[OH-],test
US20160083370A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCCCc1c[nH]c2ccccc12>>Cc1ccc(S(=O)(=O)OCCCc2c[nH]c3ccccc23)cc1,,ClCCl,,,,test
US04243609,CCCCCCCCCCCCCCCC(=O)Cl.CCOC(=O)c1ccc(N)c(F)c1>>CCCCCCCCCCCCCCCC(=O)Nc1ccc(C(=O)OCC)cc1F,,ClCCl,,,,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4cccc(C(F)(F)F)c4)nc(Cl)c3n2)cc1.COc1ccc(N)cc1OC>>COc1ccc(Nc2nc(-c3cccc(C(F)(F)F)c3)nc3cn[nH]c23)cc1OC,C1COCCO1,CO,,Cl,,test
US20120225867A1,C[N+](=O)[O-].O=Cc1ccc(Br)o1>>O=[N+]([O-])/C=C/c1ccc(Br)o1,,CO,O,Cl,[Na+].[OH-],test
US20040267012A1,C1CCNCC1.Nc1nnc(Cl)s1>>Nc1nnc(N2CCCCC2)s1,,CCO,,,,test
US20060229353A1,CCCCCCC1C(=O)NC2(C(O)C3CCCCC3)C(=O)OC12C.SCc1ccccc1>>CCCCCCC1C(=O)NC(C(=O)SCc2ccccc2)(C(O)C2CCCCC2)C1(C)O,,ClCCl,,CCN(CC)CC,,test
US20030069242A1,CCS.N#Cc1ccc(-c2ccc(Cl)cc2Cl)cc1F>>CCSc1cc(-c2ccc(Cl)cc2Cl)ccc1C#N,,CN(C)C=O,,[H][H],[H-].[Na+],test
US04433152,Cl.N=C(N)N1CCC(CCC(=O)O)CC1.O=Cc1ccc(O)cc1>>Cl.N=C(N)N1CCC(CCC(=O)Oc2ccc(C=O)cc2)CC1,,c1ccncc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20160159837A1,ClP1OC(c2ccccc2)(c2ccccc2)C(c2ccccc2)(c2ccccc2)O1.Oc1ccccc1-c1ccccc1>>c1ccc(-c2ccccc2OP2OC(c3ccccc3)(c3ccccc3)C(c3ccccc3)(c3ccccc3)O2)cc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20030018034A1,CC(=O)NCc1ccc(C(C)Cl)cc1.CC(=O)NCc1ccc(CCl)cc1.COc1ccccc1N1CCNCC1.Cl>>COc1ccccc1N1CCN(C(C)c2ccc(CNC(C)=O)cc2)CC1.Cl.Cl,,CCO,,C1COCCO1,,test
US20110059958A1,FC1(F)CCNCC1.O=C(O)c1cccc(I)c1>>O=C(c1cccc(I)c1)N1CCC(F)(F)CC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05534535,CC(C)(C)N.OC[C@@H]1C[C@H](n2c(Br)nc3cc(Cl)c(Cl)cc32)[C@@H](O)[C@H]1O>>CC(C)(C)Nc1nc2cc(Cl)c(Cl)cc2n1[C@H]1C[C@@H](CO)[C@H](O)[C@@H]1O,,CCO,,,,test
US20160075730A1,CC(=O)[C@]1(O)Cc2c(O)c3c(c(O)c2[C@@H](O[C@H]2C[C@H](N)[C@H](O)[C@H](C)O2)C1)C(=O)c1c(N)cccc1C3=O.CO[C@H](CI)OCCI>>CO[C@@H]1CN([C@H]2C[C@H](O[C@H]3C[C@](O)(C(C)=O)Cc4c(O)c5c(c(O)c43)C(=O)c3c(N)cccc3C5=O)O[C@@H](C)[C@H]2O)CCO1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20040192692A1,CC(=O)c1ccc(F)c(Br)c1.O=[Se]=O>>O=CC(=O)c1ccc(F)c(Br)c1,,C1COCCO1,O,,,test
US20040229861A1,COC(=O)[C@@H](CO[C@H](CN(CC1CC1)C(=O)OC(C)(C)C)c1ccccc1)NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N(CC1CC1)C[C@@H](OC[C@@H](NC(=O)OCc1ccccc1)C(=O)O)c1ccccc1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20070088165A1,COC(=O)C(N)(Cc1ccccc1)C(F)F>>NC(CO)(Cc1ccccc1)C(F)F,,C1CCOC1,,Cl,[BH4-].[Li+],test
US20140213578A1,NCCCN1c2ccccc2CCc2cc(Cl)ccc21.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>O=S(=O)(NCCCN1c2ccccc2CCc2cc(Cl)ccc21)c1ccc(C(F)(F)F)cc1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20090221633A1,CCOC(CN)OCC.O=Cc1cc(Cl)cc(Cl)c1>>CCOC(CN=Cc1cc(Cl)cc(Cl)c1)OCC,,Cc1ccccc1,,,,test
US20130040935A1,Cc1ccc(Br)c(C)c1C1=C(O)C2(CCC3(CC2)OCCO3)NC1=O>>Cc1ccc(Br)c(C)c1C1=C(O)C2(CCC(=O)CC2)NC1=O,,CC(C)=O,O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120028919A1,CN(C)C=O.COc1cc(C2CCN(CC(N)=O)CC2)ccc1N.COc1ccc(-c2ccc3cnc(O)nn23)c(OC)c1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1ccc(-c2ccc3cnc(Nc4ccc(C5CCN(CC(N)=O)CC5)cc4OC)nn23)c(OC)c1.O=C(O)C(F)(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20110021487A1,N#Cc1c(Cl)nc(SCc2cccc(C(N)=O)c2)c(C#N)c1-c1ccc(OC2CCOC2)cc1.O[C@@H]1CCNC1>>N#Cc1c(SCc2cccc(C(N)=O)c2)nc(N2CC[C@@H](O)C2)c(C#N)c1-c1ccc(OC2CCOC2)cc1,,C1CCOC1,,,,test
US20120156508A1,COc1cccc2c(-c3ccc(-c4ccccc4)cc3)c(C(C)(C)O)cc(O)c12>>COc1cccc2c3c(cc(O)c12)C(C)(C)c1cc(-c2ccccc2)ccc1-3,,COC(C)(C)C,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20070191370A1,COc1ccc(N)cc1OC.O=C(Cl)c1cnc(Cl)cn1>>COc1ccc(NC(=O)c2cnc(Cl)cn2)cc1OC,,ClCCl,ClCCl,CCN(CC)CC,,test
US20050059708A1,CCc1ccc(CCOc2ccc(CC(SC#N)C(=O)O)cc2)nc1>>CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1,,CS(=O)(=O)O,,O=C([O-])O.[Na+],,test
US20050256198A1,CCNCc1ccc(C(F)(F)F)cc1.COC(=O)c1ccccc1CSc1ccc(CC(=O)O)cc1>>CCN(Cc1ccc(C(F)(F)F)cc1)C(=O)Cc1ccc(SCc2ccccc2C(=O)OC)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20150376160A1,CCOC(=O)C1(c2ccc(-c3ccc(-c4sc(Cl)cc4C(N)=O)cc3C(=O)OC(C)(C)C)cc2)CC1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4sc(Cl)cc4C(N)=O)cc3C(=O)O)cc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160255837A1,FC(F)(F)c1nc(Br)cs1.O=C=O>>O=C(O)c1sc(C(F)(F)F)nc1Br,,C1CCOC1,CCOC(C)=O,CC(C)NC(C)C,[Li]CCCC,test
US20120202785A1,C[C@H](Nc1ncnc2[nH]cnc12)c1nc2ccc(F)c(Br)c2n1C.OB(O)c1ccncc1>>C[C@H](Nc1ncnc2[nH]cnc12)c1nc2ccc(F)c(-c3ccncc3)c2n1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040122098A1,C1=COCCC1.CSCC[C@@H](NC(=O)OC(C)(C)C)C(O)C(=O)O>>CSCC[C@@H](NC(=O)OC(C)(C)C)C(OC1CCCCO1)C(=O)O,,ClCCl,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20140171311A1,CN(NC(=O)c1ccc(/C=C/C(c2cc(Cl)c(Cl)c(Cl)c2)C(F)(F)F)cc1Br)C(=O)OC(C)(C)C>>CNNC(=O)c1ccc(/C=C/C(c2cc(Cl)c(Cl)c(Cl)c2)C(F)(F)F)cc1Br,,C1COCCO1,,Cl,,test
US06369069B1,Clc1cc(Br)ccc1CBr.NCc1ccccc1>>Clc1cc(Br)ccc1CNCc1ccccc1,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US06239131B1,CCOC(=O)c1cccc(NC(=O)NC2CN(C3CCCCC3)c3ccc(C)cc3N(CC(=O)c3ccccc3C)C2=O)c1>>Cc1ccc2c(c1)N(CC(=O)c1ccccc1C)C(=O)C(NC(=O)Nc1cccc(C(=O)O)c1)CN2C1CCCCC1,,C1CCOC1,CCO,O,[Li+].[OH-],test
US20150175562A1,BrBr.COC(=O)c1occ(CC2CCCCC2)c1C>>COC(=O)c1oc(Br)c(CC2CCCCC2)c1C,,CCOC(C)=O,ClCCl,,,test
US20160264554A1,CNC.Nc1ccc(S(=O)(=O)N[C@H]2CCC[C@@H](Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)C2)cc1.O=C(Cl)/C=C/CBr>>CN(C)C/C=C/C(=O)Nc1ccc(S(=O)(=O)N[C@H]2CCC[C@@H](Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)C2)cc1,,C1CCOC1,CN1CCCC1=O,CCN(C(C)C)C(C)C,ClCCl,test
US20070010528A1,CC(C)(C)OC(=O)C1CN(C(=O)OC(C)(C)C)CCN1.O=C(O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1>>CC(C)(C)OC(=O)C1CN(C(=O)OC(C)(C)C)CCN1C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1,,CC#N,CCN(CC)CC,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20100316601A1,CC1=NN(c2ccc3c(c2)C(C)(C)CC3)C(=O)C1.Cc1cc(N)c(O)c(-c2cccc(C(=O)O)c2)c1.O=N[O-]>>CC1=NN(c2ccc3c(c2)C(C)(C)CC3)C(=O)C1=NNc1cc(C)cc(-c2cccc(C(=O)O)c2)c1O,,Cl,,O=C([O-])O.[Na+],,test
US04166174,CCCCCI.COc1ccc(C(C)(C)C2CC(C)=CCN2)cc1>>CCCCCN1CC=C(C)CC1C(C)(C)c1ccc(OC)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150353553A1,CO.C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(C#N)nc(N[C@H](C)C4CCC4)c32)CC1>>COC(=N)c1nc(N[C@H](C)C2CCC2)c2c(n1)nc(N1CCOC[C@H]1c1ccccc1)n2C[C@H]1CC[C@H](C)CC1,,CO,,C[O-].[Na+],,test
US20130317110A1,CC(=O)Nc1ccc2c(c1F)CCC2=O>>Nc1ccc2c(c1F)CCC2=O,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20150038438A1,CC1CCCC(=O)c2cc3cc(CO[Si](C)(C)C(C)(C)C)n(C)c3cc21.COc1ccc(CN)c(OC)c1>>COc1ccc(CN=C2CCCC(C)c3cc4c(cc32)cc(CO[Si](C)(C)C(C)(C)C)n4C)c(OC)c1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,CCN(CC)CC,,test
US20160221990A1,O=S(=O)(N1CCN(c2ccc(/C=C/c3cc(F)cc(-c4ccncc4)c3)cc2)CC1)C(F)(F)F>>O=S(=O)(N1CCN(c2ccc(CCc3cc(F)cc(-c4ccncc4)c3)cc2)CC1)C(F)(F)F,[Pd],CCO,,,,test
US04012223,CC1(c2nnc(N=C=O)s2)CCCCC1.CNCC=O>>CN(CC=O)C(=O)Nc1nnc(C2(C)CCCCC2)s1,,CCOC(C)=O,,,,test
US20090253684A1,CN(C)C(=O)c1cc(Br)cc(C#CCCCCCc2cccc(OCCCC(=O)O)c2CCC(=O)O)c1.OB(O)c1ccccc1>>CN(C)C(=O)c1cc(C#CCCCCCc2cccc(OCCCC(=O)O)c2CCC(=O)O)cc(-c2ccccc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O,O=C([O-])[O-].[K+].[K+],test
US20070105838A1,Cl.Fc1ccc2c(c1)CNC2.O=C(Cl)c1ccc(OCCCN2CCCCC2)cc1>>Cl.O=C(c1ccc(OCCCN2CCCCC2)cc1)N1Cc2ccc(F)cc2C1,,ClCCl,,Cl,,test
US05840732,ClCCCCSc1cccc2nccn12.O=C1NC(=O)C(=Cc2cccs2)S1>>O=C1SC(=Cc2cccs2)C(=O)N1CCCCSc1cccc2nccn12,,CN(C)C=O,,O,,test
US20100048715A1,Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1ccc(N(C)C)c(N)c1.N#Cc1ccc(C(=O)Cl)cc1>>Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1ccc(N(C)C)c(NC(=O)c2ccc(C#N)cc2)c1,,CCOC(C)=O,,O=C([O-])O.[Na+],,test
US06204278B1,Nc1ccc(F)cc1F.O=C(O)CCCCCBr>>O=C(CCCCCBr)Nc1ccc(F)cc1F,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20140296237A1,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cc(Cl)c[n+]([O-])c1.C[Si](C)(C)C#N>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cc(Cl)cnc1C#N,,CC#N,CCOC(C)=O,CCN(CC)CC,[Na+].[OH-],test
US20120322785A1,CC(C)(C)OC(=O)Nc1cnc(Cl)cc1C=O.C[Mg]I>>CC(O)c1cc(Cl)ncc1NC(=O)OC(C)(C)C,,CCOCC,,C1CCOC1,,test
US20150018343A1,Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccccc1OC1CCN(C(=O)OC(C)(C)C)CC1)C3>>Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccccc1OC1CCNCC1)C3,,C1COCCO1,,Cl,,test
US05491166,C=O.O=C(O)C1Cc2ccccc2CN1>>CN1Cc2ccccc2CC1C(=O)O,,O,O=CO,Cl,,test
US04910201,ClCc1ccc(Cl)cc1.O=c1c(Cl)c(O)cnn1-c1ccc(Cl)cc1>>O=c1c(Cl)c(OCc2ccc(Cl)cc2)cnn1-c1ccc(Cl)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150119390A1,COC1(c2cccc(CO)n2)CCOCC1.COc1cc(O)c2cc(-c3cn4nc([C@H](C)F)sc4n3)oc2c1>>COc1cc(OCc2cccc(C3(OC)CCOCC3)n2)c2cc(-c3cn4nc([C@H](C)F)sc4n3)oc2c1,,C1CCOC1,CCOC(C)=O,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US04550105,[N-]=[N+]=N[C@H]1NC(=O)[C@H]1NC(c1ccccc1)(c1ccccc1)c1ccccc1>>[N-]=[N+]=N[C@H]1NC(=O)[C@H]1N,,CC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100324068A1,CCOC(=O)CCNC(=O)Cc1ccc(-c2ccc(-c3nc(C(N)=O)c(C)nc3C)cc2)c(Cl)c1>>Cc1nc(C)c(-c2ccc(-c3ccc(CC(=O)NCCC(=O)O)cc3Cl)cc2)nc1C(N)=O,,CC(C)(C)O,,[K+].[OH-],,test
US04692166,O=S(=O)(Cl)Cl.Oc1ccc2c(c1)OCO2>>Oc1cc2c(cc1Cl)OCO2,,CCOCC,,[Na+].[OH-],,test
US04628059,CI.Fc1cc(F)cc(Cn2cnnc2S)c1>>CSc1nncn1Cc1cc(F)cc(F)c1,,CO,,C[O-].[Na+],,test
US05389643,CC#CC(C)O.COC(=O)c1cc(Cl)c(NC(C)=O)cc1O>>CC#CC(C)Oc1cc(NC(C)=O)c(Cl)cc1C(=O)OC,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04404222,CC(=O)OC(C)=O.CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1>>CC(=O)N(CC(O)c1cc(Cl)c(N)c(Cl)c1)C(C)(C)C.CC(=O)O,,c1ccncc1,,,,test
US20160176861A1,ClCc1c(-c2c(Cl)cccc2Cl)noc1C1CC1.OC1C[C@@H]2COC[C@H](C1)C21OCCO1>>Clc1cccc(Cl)c1-c1noc(C2CC2)c1COC1C[C@@H]2COC[C@H](C1)C21OCCO1,,C1CCOC1,,[H-].[Na+],,test
US20120171245A1,CO[C@@H]1CCC[C@H](Nc2nc(Cl)ncc2F)[C@H]1O.Cc1ccc(S(=O)(=O)n2cc(B3OC(C)(C)C(C)(C)O3)c3cc(Cl)cnc32)cc1>>CO[C@@H]1CCC[C@H](Nc2nc(-c3cn(S(=O)(=O)c4ccc(C)cc4)c4ncc(Cl)cc34)ncc2F)[C@H]1O,[Pd],CCOC(C)=O,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US20140221652A1,CN1CCN(Cc2ccc(C(=O)O)cc2)CC1.Cl.Cl.O=S(Cl)Cl>>CN1CCN(Cc2ccc(C(=O)Cl)cc2)CC1.Cl.Cl,,ClCCl,,CN(C)C=O,,test
US20050245530A1,CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc([N+](=O)[O-])cc2F)ncn1>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(N)cc2F)ncn1,O=[Pt]=O,CCO,CO,,,test
US04988686,C=CCN.CCOC(C)=O.CO.COc1ccc(COC2C=NC(CO)=CC2=O)cc1>>C=CCn1cc(OC(c2ccccc2)c2ccccc2)c(=O)cc1CO,,CO,,,,test
US20080275067A1,Cc1cccc2nc(C(CCCCNC(=O)OCc3ccccc3)Nc3ncnc4[nH]cnc34)n(-c3ccccc3)c(=O)c12>>Cc1cccc2nc(C(CCCCN)Nc3ncnc4[nH]cnc34)n(-c3ccccc3)c(=O)c12,[Pd],CCO,,[H][H],,test
US20070167443A1,COc1ccc(C(=O)c2c[nH]c3ccccc3c2=O)cc1C.FC(F)(F)c1cccc(CBr)n1>>COc1ccc(C(=O)c2cn(Cc3cccc(C(F)(F)F)n3)c3ccccc3c2=O)cc1C,,CN(C)C=O,,,,test
US20090163512A1,COC(=O)COc1ccc(Cl)cc1C=O.O=C1Cc2ccc(Cl)cc2N1>>COC(=O)COc1ccc(Cl)cc1/C=C1\C(=O)Nc2cc(Cl)ccc21,,CO,,C1CCNC1,,test
US20100240658A1,COc1ccc(CNC(=O)c2ccc(-c3noc(-c4ccc(-c5ccccc5C)c(C)c4)n3)cc2F)c(OC)c1>>Cc1ccccc1-c1ccc(-c2nc(-c3ccc(C(N)=O)c(F)c3)no2)cc1C,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US06262040B1,CCc1nn(C2CCCC2)c2cc(C(=O)Nc3ccc(C(=O)NOCc4ccccc4)cc3)ccc12>>CCc1nn(C2CCCC2)c2cc(C(=O)Nc3ccc(C(=O)NO)cc3)ccc12,[Pd],CCOC(C)=O,CO,,,test
US04859761,CC(C)c1cc(Oc2ccccc2)cc(C(C)C)c1N=C=NC(C)(C)C.N#CN>>CC(C)c1cc(Oc2ccccc2)cc(C(C)C)c1NC(=NC(C)(C)C)NC#N,,ClCCCl,,,,test
US20070135490A1,O.OCCOCc1cccc(SC2CCCC2)c1>>O=S(c1cccc(COCCO)c1)C1CCCC1,,O,,CCO,,test
US20090215759A1,COc1cc(Nc2nc(C)cc(Cl)n2)ccc1-n1cnc(C)c1.Oc1cc(F)c(F)c(F)c1>>COc1cc(Nc2nc(C)cc(Oc3cc(F)c(F)c(F)c3)n2)ccc1-n1cnc(C)c1,,CN1CCCC1=O,,[Na+].[OH-],,test
US04387103,CCOC(=O)c1ccc(O)cc1.ClCC1CO1>>CCOC(=O)c1ccc(OCC2CO2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(CC(C)(C)CO[Si](C)(C)C(C)(C)C)c2nc(C)nn12>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(CC(C)(C)CO)c2nc(C)nn12,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110301109A1,CCCOc1ccc(N)cc1-c1nc(C(C)C)c(Br)c(=O)[nH]1.CCN=C=S>>CCCOc1ccc(NC(=S)NCC)cc1-c1nc(C(C)C)c(Br)c(=O)[nH]1,,CCO,,CCN(CC)CC,,test
US20020103242A1,CCCc1c(O)ccc2c(C(F)(F)F)noc12.CCOC(=O)C1(CC)CCc2ccc(OCCCBr)cc2O1>>CCCc1c(OCCCOc2ccc3c(c2)OC(CC)(C(=O)OCC)CC3)ccc2c(C(F)(F)F)noc12,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090281123A1,COCC(CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(N)sc12.Cl>>COCC(CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(Cl)sc12,,O,,O=N[O-].[Na+],,test
US20040082542A1,O=[N+]([O-])c1ccc(F)cc1.Oc1ccc(Cl)cc1Cl>>O=[N+]([O-])c1ccc(Oc2ccc(Cl)cc2Cl)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150361081A1,CCOC(=O)c1cc2n(n1)CCNC2=O.COc1ccc(CCl)cc1>>CCOC(=O)c1cc2n(n1)CCN(Cc1ccc(OC)cc1)C2=O,,CN(C)C=O,O,[H-].[Na+],,test
US20070244103A1,COC1CCOC1OC.NCc1ccccc1.O=C(O)CC(=O)CC(=O)O>>O=C1CC2CCC(C1)N2Cc1ccccc1,,Cl,O,CC(=O)[O-].[Na+],,test
US20100029684A1,C[C@H](N[C@H](C(=O)O)C1CC1)c1ccccc1>>C[C@H](N[C@H](CO)C1CC1)c1ccccc1,,C1CCOC1,,B,CSC,test
US20080287458A1,COC(=O)C(=O)N(c1ccccc1)c1ccccc1C(=O)CCc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1>>COC(=O)c1c(Cc2ccc(S(=O)(=O)N3CCN(C)CC3)cc2)c(=O)c2ccccc2n1-c1ccccc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US05389614,CC(=O)N([C@@H](CC(=O)O)C(=O)N[C@H](C(=O)O)C(C)C)N1C(=O)NC(=Cc2ccc(C#N)cc2)C1=O>>CC(=O)N([C@@H](CC(=O)O)C(=O)N[C@H](C(=O)O)C(C)C)N1C(=O)NC(Cc2ccc(CN)cc2)C1=O,,CO,,,,test
US06346527B1,CCOC(=O)C1=Cc2cccc(I)c2OCC1.O=Cc1ccccc1B(O)O>>CCOC(=O)C1=Cc2cccc(-c3ccccc3C=O)c2OCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,CCN(CC)CC,,test
US20090286791A1,CC(C)(C)OC(=O)NCCNC(=O)c1ccc(OCC(F)(F)F)nc1.Cl>>Cl.NCCNC(=O)c1ccc(OCC(F)(F)F)nc1,,CCOC(C)=O,,,,test
US20160244406A1,CC(C)(C)OC(=O)NC/C(=C/F)CBr.CN(C)C(=O)c1ccc(O)cc1>>CN(C)C(=O)c1ccc(OC/C(=C\F)CNC(=O)OC(C)(C)C)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090149501A1,CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3ccc(C(=O)O)cc23)C1(C)C.CCCCCCCN>>CCCCCCCNC(=O)c1ccc2c(c1)c(C(=O)C1C(C)(C)C1(C)C)cn2CC1CCOCC1,,C1CCOC1,CCOC(C)=O,O=C(n1ccnc1)n1ccnc1,,test
US04943574,CC(C)n1nnc2cc(C(=O)c3ccc(F)cc3)ccc21>>CC(C)n1nnc2cc(C(O)c3ccc(F)cc3)ccc21,,CCO,,[BH4-].[Na+],,test
US20110263603A1,CC(C)(C)OC(=O)CON.Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C=O>>Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1/C=N/OCC(=O)OC(C)(C)C,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20150119412A1,O=Cc1ccc(C2CC2)c(F)c1O.O=c1[nH]c(=O)n(Br)c(=O)n1Br>>O=Cc1cc(Br)c(C2CC2)c(F)c1O,,CN(C)C=O,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20080299076A1,BrBr.CCOc1ccccc1-n1c(CC)nc2ccccc2c1=O>>CCOc1ccccc1-n1c(C(C)Br)nc2ccccc2c1=O,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US05011932,CC(=O)c1ccncc1.NNC(=O)C1CCCCC1>>CC(=NNC(=O)C1CCCCC1)c1ccncc1,,CCO,,,,test
US20100324000A1,CC(C)(C)[Si](C)(C)O[C@@H](CNCCc1ccc(OCCC23CC4CC(CC(C4)C2)C3)cc1)c1ccc(OCc2ccccc2)c(NC=O)c1>>O=CNc1cc([C@@H](O)CNCCc2ccc(OCCC34CC5CC(CC(C5)C3)C4)cc2)ccc1OCc1ccccc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20030018034A1,CCOc1cc(OCC)nc(N2CCN(C(C)=O)CC2)n1>>CCOc1cc(OCC)nc(N2CCNCC2)n1,,CCO,,O,[Na+].[OH-],test
US20100137281A1,CCc1cc2c(=O)n(CC(=O)c3ccc(OC)cc3)c(=O)n(Cc3ccc(-c4ccccc4C#N)cc3C)c2s1.O=C([O-])O.[NH3+]O>>CCc1cc2c(=O)n(CC(=O)c3ccc(OC)cc3)c(=O)n(Cc3ccc(-c4ccccc4-c4noc(=O)[nH]4)cc3C)c2s1,,ClC(Cl)Cl,,CS(C)=O,[Cl-].[Na+],test
US20150111875A1,CC(C)(C)OC(=O)NC1CN(c2ccc3c(c2)[C@@H](Cc2ccccc2)[C@@H](N2CCC2)CC3)C1>>NC1CN(c2ccc3c(c2)[C@@H](Cc2ccccc2)[C@@H](N2CCC2)CC3)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120108619A1,CC(C)(C)OC(=O)N1CCC2(CC1)Cc1cn(C(C)(C)C)nc1C(=O)N2.Cl>>CC(C)(C)n1cc2c(n1)C(=O)NC1(CCNCC1)C2.Cl,,C1COCCO1,CCOC(C)=O,,,test
US20060154928A1,CCCCCCCCC=O.COc1ccc(C(C)(C)C)cc1NC(=N)NC(=N)N.Cl>>CCCCCCCCC1N=C(N)N=C(N)N1c1cc(C(C)(C)C)ccc1OC.Cl,,CCO,,Cl,,test
US20110275657A1,CCN(CCc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(OC)cc1)C(=O)OC>>CCN(CCc1c[nH]cn1)C(=O)NC(Cc1ccc(OC)cc1)C(=O)O,,C1CCOC1,O,[Li+].[OH-],,test
US20020028815A1,C1=C(c2cc3ccccc3[nH]2)CCC1.CCOC(=O)/C=C\C#N>>CCOC(=O)C1c2c([nH]c3ccccc23)C2=C(CCC2)C1C#N,,CCOCC,,,,test
US20130203689A1,CC/C=C\C[C@H]1C(=O)CC[C@@H]1CC(=O)O>>CCCCCC1C(=O)CCC1CC(=O)O,[Pd],C1CCOC1,,,,test
US20040242410A1,Nc1ccccc1.O=Cc1ccccc1C1C=Cc2ccccc21>>C1=CC(c2ccccc2CNc2ccccc2)c2ccccc21,,CCO,Cc1ccccc1,O,[BH4-].[Na+],test
US06653334B1,C1CCOC1.CC(C)(C)OC(=O)C(C)(C)Oc1cccc(C=O)c1>>CCOC(=O)C=Cc1cccc(OC(C)(C)C(=O)OC(C)(C)C)c1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20160108039A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.CC(O)CC1(C)OCC(CO[Si](C)(C)C(C)(C)C)N(Cc2ccccc2)C1=O>>CC(CC1(C)OCC(CO[Si](C)(C)C(C)(C)C)N(Cc2ccccc2)C1=O)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,CN(C)c1ccncc1,ClCCl,,c1c[nH]cn1,,test
US20100041657A1,Cc1c(N)cc(C(C)(C)C)c(O)c1C(=O)Nc1ccc(S(=O)(=O)C(F)(F)F)cc1Cl.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)Nc2cc(C(C)(C)C)c(O)c(C(=O)Nc3ccc(S(=O)(=O)C(F)(F)F)cc3Cl)c2C)cc1,,c1ccncc1,,,,test
US05374646,Cc1c(Br)cccc1C#N.O=C1CCC(=O)N1Br>>N#Cc1cccc(Br)c1CBr,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20160002175A1,Cc1cccc(-c2cc(Cl)nc(N)n2)c1C.NC1CC1c1ccc(Cl)cc1>>Cc1cccc(-c2cc(NC3CC3c3ccc(Cl)cc3)nc(N)n2)c1C,,CCCCO,,CCN(C(C)C)C(C)C,,test
US04895671,CCCCCCCCOc1ccc(-c2ncc(O)cn2)cc1.CC[C@H](C)CCCCCCCBr>>CCCCCCCCOc1ccc(-c2ncc(OCCCCCCC[C@@H](C)CC)cn2)cc1,,CCO,,[K+].[OH-],,test
US20150057276A1,CC(C)(C)C(=O)Nc1ccc(F)cc1F.O=Cc1ccc2nccnc2c1>>CC(C)(C)C(=O)Nc1ccc(F)c(C(O)c2ccc3nccnc3c2)c1F,,C1CCOC1,,[Li]CCCC,,test
US20070149579A1,COC(=O)c1cc2oc(=O)cc(-c3ccc(F)cc3)c2cc1C>>Cc1cc2c(-c3ccc(F)cc3)cc(=O)oc2cc1C(=O)O,,C1CCOC1,,Cl,[Li+].[OH-],test
US20160229815A1,COC(=O)c1ccc2nc(-c3ccc4c(c3)OCO4)c(N3CCC[C@@H]3C)nc2c1>>C[C@H]1CCCN1c1nc2cc(C(=O)O)ccc2nc1-c1ccc2c(c1)OCO2,,CO,O,[Na+].[OH-],,test
US05691323,CC(C)(C)OC(=O)N1CCN([C@@H]2CC[C@@H](n3c(=O)[nH]c4ccccc43)CC2)CC1>>O=c1[nH]c2ccccc2n1[C@@H]1CC[C@@H](N2CCNCC2)CC1,,Cl,,[Na+].[OH-],,test
US20120165332A1,CC(C)(C)OC(=O)NCCBr.COc1cc(Nc2ncc(Cl)c(Nc3ccccc3NS(C)(=O)=O)n2)cc(OC)c1OC>>COc1cc(Nc2ncc(Cl)c(Nc3ccccc3N(CCNC(=O)OC(C)(C)C)S(C)(=O)=O)n2)cc(OC)c1OC,,CN(C)C=O,O,[I-].[Na+],O=C([O-])[O-].[Cs+].[Cs+],test
US20070203100A1,Cc1cc(OCc2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc2)ccc1Br.O=C1CCSCC1>>Cc1cc(OCc2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc2)ccc1C1(O)CCSCC1,,C1CCOC1,,[Li]CCCC,,test
US20070287717A1,COc1ccccc1-c1nc(N2CCN(C(=O)OCC(C)C)CC2)c2sccc2n1>>CC(C)COC(=O)N1CCN(c2nc(-c3ccccc3O)nc3ccsc23)CC1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20050054633A1,CCOC(=O)[C@@](C)(F)C(=O)N[C@@H]1C(=O)N(CC2CC2)c2ccccc2-c2ccccc21>>C[C@@](F)(C(=O)O)C(=O)N[C@@H]1C(=O)N(CC2CC2)c2ccccc2-c2ccccc21,,C1CCOC1,O,[Li+].[OH-],,test
US20160222030A1,CC(=S)Nc1ccc(Cl)cc1F>>Cc1nc2ccc(Cl)cc2s1,,Cc1ccccc1,,CN(C)C=O,[H-].[Na+],test
US06613942B1,ClCCBr.O=Cc1ccc(O)c2ccccc12>>O=Cc1ccc(OCCCl)c2ccccc12,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US08080558B2,COc1cc2ncnc(-c3nnn[nH]3)c2cc1OC.Cn1ccnc1CCl>>COc1cc2ncnc(-c3nnnn3Cc3nccn3C)c2cc1OC,,CC(=O)N(C)C,,CCN(CC)CC,,test
US20030187001A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COc1cc(Br)ccc1NC(=O)OC(C)(C)C>>COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1NC(=O)OC(C)(C)C,,CN(C)C=O,,ClCCl,CC(=O)[O-].[K+],test
US20100249075A1,COc1ccccc1C1CCCCC1CC=O.O=[Cr](=O)=O>>COc1ccccc1C1CCCCC1CC(=O)O,,CC(C)=O,,O=S(=O)(O)O,,test
US20090004209A1,COC(=O)c1cccc(O)c1C(=O)OC.Cc1cccc(CBr)c1>>COC(=O)c1cccc(OCc2cccc(C)c2)c1C(=O)OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120214803A1,COC(=O)c1ccnc2c3c(ccc12)-c1ccccc1S(=O)(=O)N3.N>>NC(=O)c1ccnc2c3c(ccc12)-c1ccccc1S(=O)(=O)N3,,CO,,,,test
US20120190701A1,CC(C)(C)OC(=O)OC(C)(C)C.O=Cc1c[nH]c2cccc(F)c12>>CC(C)(C)OC(=O)n1cc(C=O)c2c(F)cccc21,CN(C)c1ccncc1,O,,CC#N,CCN(CC)CC,test
US20160038504A1,Cc1ccc(N)cc1-c1cc(C2=CCOCC2)c(=O)n(C)n1>>Cc1ccc(N)cc1-c1cc(C2CCOCC2)c(=O)n(C)n1,[Pd],CCO,,,,test
US06329382B1,CCOC(=O)c1nc2c(C#N)cnn2c2c1CCN2C1CCCC1>>N#Cc1cnn2c3c(c(C(=O)O)nc12)CCN3C1CCCC1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20100004240A1,CC(C)Cn1cc(-c2nc(-c3nc4cc(CO)ccc4[nH]3)co2)c2cc(Cl)ccc21>>CC(C)Cn1cc(-c2nc(-c3nc4cc(C=O)ccc4[nH]3)co2)c2cc(Cl)ccc21,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20060223849A1,Nc1ccc(F)cc1.Nc1cccc2nc(NC(=O)c3cc4ccccc4cn3)[nH]c12.O=C(n1ccnc1)n1ccnc1>>O=C(Nc1ccc(F)cc1)Nc1cccc2nc(NC(=O)c3cc4ccccc4cn3)[nH]c12,,CN(C)C=O,,,,test
US20160122285A1,COCc1cc(N=Nc2ccccc2COC)ccc1N>>COCc1cc(N)ccc1N,[Zn],CO,,O=C[O-].[NH4+],,test
US20080019915A1,Cc1ccc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)nc1Cl.OB(O)C1=CCCCC1>>Cc1ccc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)nc1C1=CCCCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20140221344A1,CC(C)(C)OC(=O)N[C@H]1CCCNC1.Nc1cncnc1Cl>>CC(C)(C)OC(=O)N[C@H]1CCCN(c2ncncc2N)C1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090156808A1,CC1(C)CCCC(C)(C)N1.Clc1nsnc1Cl>>CC1(C)CCCC(C)(C)N1SN=C(Cl)C#N,,COC(C)(C)C,,O,[Li]CCCC,test
US05308857,CC(=O)NCc1ccc(-c2csc(NC(=S)NC(=O)c3ccccc3)n2)o1>>NCc1ccc(-c2csc(NC(N)=S)n2)o1,,CCO,Cl,,,test
US20130131035A1,CC(O)C1CN(C(=O)OC(C)(C)C)C1.Oc1ccc(Cl)cc1>>CC(Oc1ccc(Cl)cc1)C1CN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05618821,COC(=O)C=Cc1ccc(OC)nc1>>COC(=O)CCc1cccnc1OC,[Pd],,,CCOC(C)=O,[H][H],test
US04243805,CCOC(=O)N1CCN(CCc2ccc(F)cc2)CC1>>Fc1ccc(CCN2CCNCC2)cc1,,CCO,,[K+].[OH-],,test
US20130143907A1,CCOC(=O)c1cnn([C@H]2CCOC2)c1-c1ccc(-c2c(C)cnc(OC)c2C)cc1[N+](=O)[O-]>>COc1ncc(C)c(-c2ccc3c(c2)[nH]c(=O)c2cnn([C@H]4CCOC4)c23)c1C,,CCO,,[Cl-].[NH4+],,test
US20160264567A1,CS(=O)(=O)Cl.OCc1cc(Cl)nc(C2CC2)c1C(F)(F)F>>CS(=O)(=O)OCc1cc(Cl)nc(C2CC2)c1C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US06696110B1,COc1ccc(B(O)O)cc1.N#Cc1ccc(Br)s1>>COc1ccc(-c2ccc(C#N)s2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20060154930A1,C=CCC(C)C(=O)OCC.O=[O+][O-]>>CCOC(=O)C(C)CC=O,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110034507A1,CCOC(=O)c1ccc(-c2cc3cc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)ccc3s2)cc1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2sc(-c3ccc(C(=O)O)cc3)cc2c1,,C1CCOC1,CO,[Na+].[OH-],,test
US20110028447A1,COC(=O)c1nn(Cc2ccc(F)cc2)c2ccccc12>>O=C(O)c1nn(Cc2ccc(F)cc2)c2ccccc12,,CO,,[Na+].[OH-],,test
US20120122842A1,BrCc1ccccc1.CC(C)(C)OC(=O)N[C@@H]1C[C@@H](C(=O)O)C1>>CC(C)(C)OC(=O)N[C@@H]1C[C@@H](C(=O)OCc2ccccc2)C1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040131971A1,C=C(C)C(=O)O.CC(C)=O.O.O=C1OC(=O)[C@H]2CCCC[C@@H]12>>C=C(C)C(=O)OCCOC(=O)C1CCCCC1C(=O)O,,O,,,,test
US20100305096A1,CC(C)C(=O)Cl.CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CCNCC3)n(C)c2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CCN(C(=O)C(C)C)CC3)n(C)c2n1,,ClCCl,,CCN(CC)CC,,test
US20120101136A1,C[Si](C)(C)CCOCCl.Cc1cc(O)ccc1C#N>>Cc1cc(OCOCC[Si](C)(C)C)ccc1C#N,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070049603A1,O=[N+]([O-])c1ccc2c(OCc3ccccc3)cncc2c1>>Nc1ccc2c(OCc3ccccc3)cncc2c1,[Zn],C1CCOC1,CCOC(C)=O,[Cl-].[NH4+],,test
US20130338133A1,Brc1cc(Br)c2ncc(I)n2n1.C[S-]>>CSc1cc(Br)nn2c(I)cnc12,,CN1CCCC1=O,,O,,test
US05631401,N#Cc1ccc(CBr)cc1.c1cc[nH]c1>>N#Cc1ccc(Cn2cccc2)cc1,,CN(C)C=O,,,,test
US20110251190A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1=N[C@@]2(CS1)c1cc(Br)ccc1Oc1cnc(Cl)cc12>>CC(C)(C)OC(=O)NC1=N[C@@]2(CS1)c1cc(Br)ccc1Oc1cnc(Cl)cc12,,C1COCCO1,O,O=C([O-])O.[Na+],,test
US20110136838A1,CC(C)(C)OC(=O)NCCCNc1nc(Nc2cccc(CCCN(C(=O)[O-])C(C)(C)C)c2)c2c(=O)[nH]ccc2n1>>NCCCNc1nc(Nc2cccc(CCCN)c2)c2c(=O)[nH]ccc2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120252807A1,CC(=O)C1Cc2ccccc2C1.N>>CC(N)C1Cc2ccccc2C1,,CO,,CC(=O)O,[BH4-].[Na+],test
US05156763,COc1cc(F)c(C(N)=O)c(F)c1>>COc1cc(F)c(C#N)c(F)c1,,CN(C)C=O,,O=S(Cl)Cl,,test
US04045433,CCOC=O.CN1C(=O)CNC(c2ccccc2)c2cc(Cl)ccc21>>CN1C(=O)CN(C=O)C(c2ccccc2)c2cc(Cl)ccc21,,Clc1ccccc1,,,,test
US20110312926A1,CO[C@H]1CC[C@H]2[C@@H]3CCC4CC=CC[C@]4(C)[C@H]3CC[C@]12C.O=C(OO)c1cccc(Cl)c1>>CO[C@H]1CC[C@H]2[C@@H]3CCC4C[C@@H]5O[C@@H]5C[C@]4(C)[C@H]3CC[C@]12C,,ClCCl,,,,test
US20110306607A1,CC(C)(C)OC(=O)N1CCC2(CC1)Oc1cc(C#N)ccc1-n1cccc12>>N#Cc1ccc2c(c1)OC1(CCNCC1)c1cccn1-2,,Cl,,C1COCCO1,,test
US20020147212A1,CN(C)C=O.COc1ccc(OC(F)(F)F)cc1>>COc1ccc(OC(F)(F)F)cc1C=O,,C1CCOC1,,[Li]C(C)(C)C,,test
US20060258689A1,Clc1ncnc2c1CN(Cc1ccccc1)CC2.Nc1ccccc1>>c1ccc(CN2CCc3ncnc(Nc4ccccc4)c3C2)cc1,,CC#N,,,,test
US20120088755A1,COc1ccc2c(c1)CCN(C1CCNCC1)C(=O)N2.Cc1cc(Nc2cc(Cl)ncn2)cc2oc(=O)n(C)c12>>COc1ccc2c(c1)CCN(C1CCN(c3cc(Nc4cc(C)c5c(c4)oc(=O)n5C)ncn3)CC1)C(=O)N2,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20090069576A1,COC(=O)CCOCCc1ccc2sccc2c1>>O=C(O)CCOCCc1ccc2sccc2c1,,O,,CO,[K+].[OH-],test
US04433152,Cl.N=C(N)N1CCC(CCC(=O)O)CC1.O=S(Oc1ccc(Cl)cc1)Oc1ccc(Cl)cc1>>Cl.N=C(N)N1CCC(CCC(=O)Oc2ccc(Cl)cc2)CC1,,c1ccncc1,,CN(C)C=O,,test
US20060173065A1,COC(=O)CCCCCOc1ccc(OC(=O)COCc2ccccc2)cc1>>COC(=O)CCCCCOc1ccc(OC(=O)CO)cc1,[Pd],CO,,,,test
US20070269664A1,CC(C)[Si](OCCc1cc(F)cc(F)c1)(C(C)C)C(C)C.CN(C)C=O>>CC(C)[Si](OCCc1cc(F)c(C=O)c(F)c1)(C(C)C)C(C)C,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20140039197A1,NC(=NO)c1ccccc1.O=C(Cl)c1cccs1>>c1ccc(-c2noc(-c3cccs3)n2)cc1,,CC(C)=O,,O,[Na+].[OH-],test
US05246915,COC(=O)CNC1CCCc2ccc(OC)cc21.O=CO>>COC(=O)CN(C=O)C1CCCc2ccc(OC)cc21,,O=CO,,CC(=O)OC(C)=O,,test
US20160002228A1,Cc1ccc(S(=O)(=O)n2cc(C=O)c3cc(Br)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(CO)c3cc(Br)cnc32)cc1,,CO,,[BH4-].[Na+],,test
US20140213642A1,C=CCOc1cc(Cl)c(Cc2ccc(OCC)cc2)cc1[C@@H]1O[C@H](COCCCCCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>C=CCOc1cc(Cl)c(Cc2ccc(OCC)cc2)cc1[C@@H]1O[C@H](COCCCCCO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04025538,Cc1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1C(=O)Cl.N>>Cc1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1C(N)=O,,CC(C)=O,,O,,test
US20090143371A1,Cc1cccc(F)n1.Cc1onc(-c2ccccc2)c1CO>>Cc1cccc(OCc2c(-c3ccccc3)noc2C)n1,,C1CCOC1,,[H-].[Na+],,test
US20070213336A1,CCCCCN=C=O.NCc1cccc(Br)c1>>CCCCCNC(=O)N(C)c1cccc(Br)c1,,ClCCl,,CCN(CC)CC,,test
US20100221182A1,CC(C)(C)OC(=O)N1CCN(c2cccc(CF)c2)CC1.N=C(N)n1cccn1>>N=C(N)N1CCN(c2cccc(CF)c2)CC1,,C1COCCO1,Cl,CCN(C(C)C)C(C)C,,test
US20090093484A1,CCOC(=O)COc1ccc(OC)c2occc12>>CCOC(=O)COc1ccc(O)c2occc12,,ClCCl,,BrB(Br)Br,O,test
US20110118262A1,Cc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)c(C(F)(F)F)cc1C(=O)N(C(=N)N)C(=O)OCc1ccccc1>>Cc1cc(C2CCNCC2)c(C(F)(F)F)cc1C(=O)NC(=N)NC(=O)OCc1ccccc1,,C1COCCO1,,CO,Cl,test
US20080171775A1,CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1c1ccccc1Cl.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1[C@H](C(=O)O)C[C@@H]2CCC[C@@H]21>>CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1c1ccccc1Cl.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1[C@H](C(=O)O)C[C@@H]2CCC[C@@H]21,,CCOC(C)=O,,,,test
US03969373,O=C(O)CCc1ccc(C=CC(=O)c2ccccc2)cc1.OO>>O=C(O)CCc1ccc(C2OC2C(=O)c2ccccc2)cc1,,[Na+],[OH-],Cl,,test
US20060276508A1,COc1cc(OCC2COC(C)(C)O2)cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)c1.O=C(O)C(F)(F)F>>COc1cc(OCC(O)CO)cc(C(=O)NC2CCNCC2)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US04021451,CC1(CC(=O)O)OCCc2c1[nH]c1c3c(ccc21)CCCC3.CNC>>CN(C)C(=O)CC1(C)OCCc2c1[nH]c1c3c(ccc21)CCCC3,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US20100249120A1,COC(OC)N(C)C.COc1ccc(Cn2nccc2N)cc1.O=C1C=CC(=O)N1>>COc1ccc(Cn2ncc3c4c(cnc32)C(=O)NC4=O)cc1,,CC(=O)O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US06350749B1,Cc1ccnc2c1C(=O)CC(c1ccccn1)C2.Cl.N=C(N)NN>>Cc1ccnc2c1C(=NNC(=N)N)CC(c1ccccn1)C2.Cl,,CCO,,Cl,O,test
US20160264567A1,O=C1c2ccccc2C(=O)N1Cc1cc(C2CC(OC(F)(F)F)C2)ncc1F>>NCc1cc(C2CC(OC(F)(F)F)C2)ncc1F,,CO,,NN,O,test
US05872137,O=C(OCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl)c1ccccc1>>OCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl,,CO,,[K+].[OH-],,test
US20100292276A1,Cl.FC(F)(F)c1ccccc1-c1ccc2[nH]c(/C=C/C3CCOCC3)nc2c1>>Cl.FC(F)(F)c1ccccc1-c1ccc2[nH]c(/C=C/C3CCOCC3)nc2c1,,CCO,,CC(C)O,,test
US20150191461A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.COc1ccc(CN2CC(C(C)OS(C)(=O)=O)CC2=O)c(OC)c1>>COc1ccc(CN2CC(C(C)n3cc(B4OC(C)(C)C(C)(C)O4)cn3)CC2=O)c(OC)c1,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20140213578A1,CC(CN)CN1c2ccccc2CCc2ccccc21.O=S(=O)(Cl)c1ccc(Cl)cc1>>CC(CNS(=O)(=O)c1ccc(Cl)cc1)CN1c2ccccc2CCc2ccccc21,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20150239900A1,CC(C)(C)OC(=O)N1CCN(c2ncnc3c(F)c(Br)c(Cl)cc23)CC1.CO[Na]>>COc1c(Br)c(Cl)cc2c(N3CCN(C(=O)OC(C)(C)C)CC3)ncnc12,,C1CCOC1,,,,test
US20040242572A1,C=O.CC#N.NC1CCN(Cc2ccc(CCNC(=O)c3ccc(-c4ccc(Cl)cc4)cc3)cc2)C1>>CN(C)C1CCN(Cc2ccc(CCNC(=O)c3ccc(-c4ccc(Cl)cc4)cc3)cc2)C1,CC(=O)O,CC#N,CCOC(C)=O,[Na+].[OH-],,test
US20120101134A1,CC(C)Oc1ccc(-c2nnc(Br)o2)cc1C#N.CCOC(=O)CCCc1cccc(B2OC(C)(C)C(C)(C)O2)c1CC>>CCOC(=O)CCCc1cccc(-c2nnc(-c3ccc(OC(C)C)c(C#N)c3)o2)c1CC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20080319080A1,COc1cc(C=O)cc(F)c1OCc1ccccc1.O=[Mn](=O)(=O)[O-]>>COc1cc(C(=O)O)cc(F)c1OCc1ccccc1,,CC(C)=O,,O,,test
US04647574,CCCCOC(=O)C=O.CNC(N)=O>>CN1C(=O)NC(=O)C1O,,CC(=O)O,,O,,test
US20120329791A1,CN(C)C(=O)C1CCN(c2cccc(-c3ccc4nc(-c5cccnc5N)n(-c5ccc(C6(NC(=O)OC(C)(C)C)CCC6)cc5)c4n3)c2)CC1.Cl>>CN(C)C(=O)C1CCN(c2cccc(-c3ccc4nc(-c5cccnc5N)n(-c5ccc(C6(N)CCC6)cc5)c4n3)c2)CC1.Cl,,CCOC(C)=O,,CO,,test
US20030045532A1,CI.OC1CCN(c2nc3c(-c4ccccc4F)nnn3c3ccccc23)CC1>>COC1CCN(c2nc3c(-c4ccccc4F)nnn3c3ccccc23)CC1,,CC(=O)N(C)C,O,[H-].[Na+],,test
US20130190332A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4ccc(CCl)cn4c3-c3ccccc3)cc2)CCC1.COCCN>>COCCNCc1ccc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)n2c1,,C1CCOC1,,,,test
US20160207926A1,CCn1c(C(=O)OC)nc2c(N[C@H]3CCN(C(=O)OC(C)(C)C)C3)ncnc21>>CCn1c(C(=O)OC)nc2c(N[C@H]3CCNC3)ncnc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090036492A1,CCCI.Cc1c(C)c(C=O)c2ccccc2c1O>>CCCOc1c(C)c(C)c(C=O)c2ccccc12,,CN(C)C=O,,[H-].[Na+],,test
US20120142705A1,CC(C)CC(C(=O)O)N1C(=O)C(=O)c2cc(OC(F)(F)F)ccc21.Nc1ccccn1>>CC(C)CC(C(=O)Nc1ccccn1)N1C(=O)C(=O)c2cc(OC(F)(F)F)ccc21,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20070032497A1,COc1ccc(-c2ccc(Cl)cc2)c(CCl)c1.Oc1ccc(I)cc1>>COc1ccc(-c2ccc(Cl)cc2)c(COc2ccc(I)cc2)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070099990A1,Cc1c(C)c2c(c(C)c1NC=O)OC(C)(C)C2=O.Cl[Mg]Cc1ccccc1>>Cc1c(C)c2c(c(C)c1NC=O)OC(C)(C)C2(O)Cc1ccccc1,,C1CCOC1,,O,,test
US20040127574A1,O=C1NC(Cc2cccc(OC(F)(F)C(F)F)c2)C(c2cccc(F)c2)O1>>NC(Cc1cccc(OC(F)(F)C(F)F)c1)C(O)c1cccc(F)c1,,CCO,,[Na+].[OH-],,test
US20070015743A1,Cc1ccc(Oc2ccc(N)cc2C)cn1.Fc1cccc2ncnc(Cl)c12>>Cc1ccc(Oc2ccc(Nc3ncnc4cccc(F)c34)cc2C)cn1,,CC#N,,C1COCCO1,Cl,test
US20110009454A1,Cc1cccc(CN)c1.Nc1ncccc1C(=O)O>>Cc1cccc(CNC(=O)c2cccnc2N)c1,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20030073841A1,COc1cc2c(c3c1c(=O)c1cc4ccccc4c(N)c1n3C)C=CC(C)(C)O2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1cc2c(c3c1c(=O)c1cc4ccccc4c(NC(=O)C(F)(F)F)c1n3C)C=CC(C)(C)O2,,CO,c1ccncc1,,,test
US20070129368A1,COC(=O)c1ccc(NC(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1.NO>>CC1(C)CCC(C)(C)c2cc(C(=O)Nc3ccc(C(=O)NO)cc3)ccc21,,CO,,,,test
US20150133428A1,CC1(F)CC(C)(C(=O)O)C1.NC(=O)c1c(-c2ccc(F)c(Cl)c2)nn2c1CNCC2.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC1(F)CC(C)(NC(=O)N2CCn3nc(-c4ccc(F)c(Cl)c4)c(C(N)=O)c3C2)C1,,Cc1ccccc1,O,C1CCOC1,,test
US04523030,COC(=O)C1=Cc2ccc(O)cc21.O=C(Cl)c1ccccc1>>COC(=O)C1=Cc2ccc(OC(=O)c3ccccc3)cc21,,ClCCl,,CCN(CC)CC,O,test
US20080009482A1,CCOc1cc(C(=O)O)ccc1N.CN1C(=O)CCN(C2CCCC2)c2nc(N)ncc21>>CCOc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CCC(=O)N2C,,CCO,,Cl,O,test
US04195093,COC(=O)COc1ccc(C(=O)c2cccs2)c2c1CCCC2>>O=C(O)COc1ccc(C(=O)c2cccs2)c2c1CCCC2,,CCO,O,[K+].[OH-],,test
US04595677,CC[C@H](C)[C@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)OC>>CC[C@H](C)[C@H](NC(=O)C[C@H](O)[C@@H](N)CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)OC,,CO,,O=C=O,,test
US06764829B2,CC(=O)O[C@@H]1O[C@H](COC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1.O=C1CCCc2c(O)cccc21>>O=C(OC[C@H]1O[C@@H](Oc2cccc3c2CCCC3=O)[C@H](OC(=O)c2ccccc2)[C@@H]1OC(=O)c1ccccc1)c1ccccc1,,ClCCl,,FB(F)F,,test
US04806141,CCON=C(CC)C1=C(O)CC(c2c(OC)cc(OC)cc2OC)CC1=O.O=C(Cl)c1ccccc1>>CCON=C(CC)C1=C(OC(=O)c2ccccc2)CC(c2c(OC)cc(OC)cc2OC)CC1=O,,CC(C)=O,,[Na+].[OH-],,test
US20150218181A1,C#Cc1ccc2cnc(Cl)cc2c1.C[Si](C)(C)N=[N+]=[N-]>>Clc1cc2cc(-c3cn[nH]n3)ccc2cn1,,CCOC(C)=O,CN(C)C=O,,,test
US20100240702A1,CCCC(CC(=O)OCC)n1c(=O)n(Cc2cc(C)n3cccc(C)c23)c2ccccc21>>CCCC(CC(=O)O)n1c(=O)n(Cc2cc(C)n3cccc(C)c23)c2ccccc21,,C1COCCO1,O,[Li+].[OH-],,test
US20100121048A1,Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@H]2Cc2ccc(O)cc2)c(-c2ccccc2)n1-c1ccccc1.N#CCCl>>Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@H]2Cc2ccc(OCC#N)cc2)c(-c2ccccc2)n1-c1ccccc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070142386A1,CCC[C@H](CO)Nc1nc(S(=O)(=O)Cc2ccccc2)nc2[nH]c(=O)sc12.CN(c1cccc(CO)c1)S(C)(=O)=O>>CCC[C@H](CO)Nc1nc(OCc2cccc(N(C)S(C)(=O)=O)c2)nc2[nH]c(=O)sc12,,C1CCOC1,,[Li]CCCC,,test
US20070017040A1,O=[N+]([O-])c1ccc(CNc2ccccn2)cc1O>>Nc1ccc(CNc2ccccn2)cc1O,[Pd],C1CCOC1,CCO,NN,O,test
US20070254931A1,CCOC(=O)/C=C/c1ccc(CCCc2csc(NC(C)=O)n2)cc1>>CCOC(=O)CCc1ccc(CCCc2csc(NC(C)=O)n2)cc1,[Pd],C1CCOC1,,CO,,test
US20080293742A1,COc1nc(F)cnc1NS(=O)(=O)c1cccc(F)c1.ClC(Cl)(Cl)C(Cl)(Cl)Cl>>COc1nc(F)cnc1NS(=O)(=O)c1cccc(F)c1Cl,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20070082912A1,CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccc(F)cc2)c1>>Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2)n1-c1cccc(C(=O)O)c1,,CCOC(C)=O,,CCO,[Na+].[OH-],test
US20090069340A1,CC(C)(C)OC(=O)N1CCC(C(=O)O)(c2ccccc2)CC1.Cn1c(CBr)c(Br)c(=O)n1-c1ccccc1>>Cn1c(COC(=O)C2(c3ccccc3)CCN(C(=O)OC(C)(C)C)CC2)c(Br)c(=O)n1-c1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US05869485,COc1cc(-c2cn(-c3cccc(OCCn4ccnc4)c3)c3ncnc(N)c23)ccc1OCc1ccccc1>>COc1cc(-c2cn(-c3cccc(OCCn4ccnc4)c3)c3ncnc(N)c23)ccc1O,[Pd],C1CCOC1,,CCO,[H][H],test
US20140005146A1,Brc1ccc(Br)cc1.O=C1COCCN1>>O=C1COCCN1c1ccc(Br)cc1,[Cu]I,C1COCCO1,,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20070249607A1,CC(C)(C)OC(=O)N1CCC(COCc2cc(-n3nnnc3C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)CC1>>FC(F)(F)c1cc(COCC2(c3ccccc3)CCNCC2)cc(-n2nnnc2C(F)(F)F)c1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100099725A1,CCOC(=O)C(C)(C)Oc1ccc(OCc2nn(-c3ccc(C(F)(F)F)cc3)c(=O)[nH]2)cc1C.COCCCl>>CCOC(=O)C(C)(C)Oc1ccc(OCc2nn(-c3ccc(C(F)(F)F)cc3)c(=O)n2CCOC)cc1C,,CC#N,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US06177440B1,CC(C)(C)OC(=O)COc1cccc2c1c1c(C(N)=O)cccc1n2Cc1ccccc1Cl>>NC(=O)c1cccc2c1c1c(OCC(=O)O)cccc1n2Cc1ccccc1Cl,,O=C(O)C(F)(F)F,,,,test
US20140045862A1,COc1ccc(CN(c2ccncn2)S(=O)(=O)c2cc(F)c(O[C@H]3CC(C)(C)CC[C@@H]3c3ccnn3C)cc2F)c(OC)c1>>Cn1nccc1[C@H]1CCC(C)(C)C[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20050250753A1,CC(=O)N1Cc2ccc(Br)cc2CC(O)c2ccccc21>>O=C1Cc2cc(Br)ccc2CNc2ccccc21,O=[Mn]=O,CO,,,,test
US04182624,CP(C)(=O)CCl.O=C(O)c1cncn1C(c1ccccc1)c1ccccc1>>CP(C)(=O)COC(=O)c1cncn1C(c1ccccc1)c1ccccc1,,CN(C)C=O,,[Na],,test
US20040009966A1,C=CCOC(=O)NC1CC(=O)OC1OCC.O=C(O)CN1CC=CCC(NC(=O)c2nccc3ccccc23)C1=O>>CCOC1OC(=O)CC1NC(=O)CN1CC=CCC(NC(=O)c2nccc3ccccc23)C1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,ClCCl,On1nnc2ccccc21,,test
US20050154001A1,CCOC(=O)C1(C(CN)c2ccccc2)CCN(Cc2ccccc2)CC1>>O=C1NCC(c2ccccc2)C12CCN(Cc1ccccc1)CC2,,Cc1ccccc1,,,,test
US04985458,C=Cc1ccc(OC)c(OC)c1>>CCc1ccc(OC)c(OC)c1,[Pd],CO,,[H][H],,test
US20050059638A1,CC(C)(C)NO.Cc1ncc(CO)c(C=O)c1O>>Cc1ncc(CO)c(C=[N+]([O-])C(C)(C)C)c1O,,Cc1ccccc1,,Cl,,test
US03937824,CN(C)C(=O)Cl.CONC(=O)CCl>>CON=C(CCl)OC(=O)N(C)C,,c1ccccc1,,CCN(CC)CC,,test
US20090233965A1,CN1CCC(O)CC1.COC(=O)C(C)(c1cccnc1)C1CCCC1>>CN1CCC(OC(=O)C(C)(c2cccnc2)C2CCCC2)CC1,,CCCCCCC,,,,test
US20140243302A1,CN(C)c1ncc([N+](=O)[O-])cc1F>>CN(C)c1ncc(N)cc1F,[Ni],CO,,,,test
US20100120882A1,N#CCCl.Oc1cc(F)cc(F)c1>>N#CCOc1cc(F)cc(F)c1,,CC#N,,[I-].[K+],,test
US06806230B1,CNC(c1cncnc1C(F)(F)F)C(C)C.O=C(Cl)Cc1ccccc1>>CC(C)C(c1cncnc1C(F)(F)F)N(C)C(=O)Cc1ccccc1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US06110933,CCCCCCCCCCCCC[C@@H](CC(N)=O)OC(=O)[C@H](CCCC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C.Cl>>CCCCCCCCCCCCC[C@@H](CC(N)=O)OC(=O)[C@@H](N)CCCC(=O)OCc1ccccc1.Cl,,CCOC(C)=O,CCOCC,,,test
US20040072859A1,Cc1nc2c(N)nc3ccccc3c2n1CCOCCN.O=C=NC1CCCCC1>>Cc1nc2c(N)nc3ccccc3c2n1CCOCCNC(=O)NC1CCCCC1,,c1ccncc1,,,,test
US20080176881A1,CI.Cc1cc([N+](=O)[O-])c(OC(C)C)cc1-c1ccncc1>>Cc1cc([N+](=O)[O-])c(OC(C)C)cc1-c1cc[n+](C)cc1.[I-],,C1CCOC1,,,,test
US20080009523A1,CCOC(=O)c1cc(C#N)c(Cl)nc1C.NS(=O)(=O)C1CCNCC1>>CCOC(=O)c1cc(C#N)c(N2CCC(S(N)(=O)=O)CC2)nc1C,,CCO,O,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20130158038A1,Nc1ccc(F)cc1.O=C(CBr)c1ccc(F)cc1>>O=C(CNc1ccc(F)cc1)c1ccc(F)cc1,,C1CCOC1,,,,test
US20140336185A1,COc1ccc(CC(=O)Nc2ccc(C(=O)N(CC(=O)OC(C)(C)C)Cc3ccc(C(=N)NO)cc3)cc2)c(C(F)(F)F)c1.Cc1ccc(C#CC(=O)Cl)cc1>>COc1ccc(CC(=O)Nc2ccc(C(=O)N(CC(=O)O)Cc3ccc(-c4noc(C#Cc5ccc(C)cc5)n4)cc3)cc2)c(C(F)(F)F)c1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,,test
US20090227570A1,CC(C)N=C=O.Nc1ccc2nc(N[C@@H]3CCc4ccccc43)ccc2c1>>CC(C)NC(=O)Nc1ccc2nc(N[C@@H]3CCc4ccccc43)ccc2c1,,Cc1ccccc1,,,,test
US05633281,CC(C)(C)OC(=O)N[C@H](CO)C(c1ccccc1)c1ccccc1.FC(F)(F)c1cc(CBr)cc(C(F)(F)F)c1>>CC(C)(C)OC(=O)N[C@H](COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(c1ccccc1)c1ccccc1,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20160075713A1,CC(C)(C)OC(=O)NC1CCN(CC(F)(F)c2ccccn2)CC1>>NC1CCN(CC(F)(F)c2ccccn2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05618970,C=C(COCCOC)C(=O)OC(C)(C)C.O=S(=O)(I)c1ccc(Br)cc1>>COCCOC/C(=C\S(=O)(=O)c1ccc(Br)cc1)C(=O)OC(C)(C)C,,ClCCl,O,CCN(CC)CC,,test
US20120059030A1,COc1cc(C(=O)O)ccc1-n1cnc(C)c1.NN>>COc1cc(C(=O)NN)ccc1-n1cnc(C)c1,,C1CCOC1,,O,,test
US20110034507A1,CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CCl.COC(=O)c1cc(-c2ccc3cc(O)ccc3c2)ccc1F>>COC(=O)c1cc(-c2ccc3cc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)ccc3c2)ccc1F,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20080070935A1,CC1(C)CC(=O)C(C(=O)CC2CC2)C(=O)C1.NNc1ccc2c(N)ncnc2c1>>CC1(C)CC(=O)c2c(CC3CC3)nn(-c3ccc4c(N)ncnc4c3)c2C1,,CCO,,,,test
US20120277150A1,CN1CC2(CCNCC2)c2ccccc21.O=C(O)c1ccc(CBr)cc1>>CN1CC2(CCN(Cc3ccc(C(=O)O)cc3)CC2)c2ccccc21,,CCO,,CCN(C(C)C)C(C)C,,test
US20150119373A1,CCC1(C(=O)[O-])CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1,,C1CCOC1,CO,[Na+].[OH-],,test
US20100130558A1,FC(F)(F)c1ccc(Br)nc1.N[C@H]1CC[C@@H]2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3Cl)C[C@H]12>>O=S(=O)(c1ccc(C(F)(F)F)cc1Cl)N1C[C@H]2CC[C@H](Nc3ccc(C(F)(F)F)cn3)[C@H]2C1,,CCO,,CCN(CC)CC,,test
US20020107390A1,Cc1cc([N+](=O)[O-])cc(C)c1Oc1ccc(OCc2ccccc2)c(S(=O)(=O)NCC(C)(C)C)c1>>Cc1cc(N)cc(C)c1Oc1ccc(OCc2ccccc2)c(S(=O)(=O)NCC(C)(C)C)c1,[Pd],C1CCOC1,,,,test
US20160023991A1,CCOC(=O)COCCCOc1ccccc1CN(C(=O)c1ccc(-c2ccco2)cc1)C(C)C>>CC(C)N(Cc1ccccc1OCCCOCC(=O)O)C(=O)c1ccc(-c2ccco2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20040209921A1,Brc1ccccn1.O=C1CCC1>>OC1(c2cccnc2Br)CCC1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20150218156A1,O=c1[nH]c(=O)n(CCc2ccccc2)nc1O>>Cn1nc(O)c(=O)[nH]c1=O,,CO,,,,test
US20110071197A1,O=C(Cl)C(=O)Cl.O=C(O)c1ccc(OC2CCCC2)cc1>>O=C(Cl)c1ccc(OC2CCCC2)cc1,,Cc1ccccc1,,,,test
US20050228002A1,O=C1CCC(=O)N1I.O=c1cc(CCl)nc2ccccn12>>O=c1c(I)c(CCl)nc2ccccn12,,CC#N,,,,test
US03957799,ClP(Cl)(Cl)(Cl)Cl.O=S(=O)(O)CSc1ccccc1Br>>ClCSc1ccccc1Br,,CCOCC,,[Na],,test
US20110136875A1,CCOC(=O)/C=C/c1ccn(-c2ccc(Br)cc2)c1-c1ccc(C(N)=O)cc1C>>CCOC(=O)CCc1ccn(-c2ccc(Br)cc2)c1-c1ccc(C(N)=O)cc1C,,CCO,,[BH4-].[Na+],,test
US20100105658A1,Cl.NC(=O)c1nc(NC(=O)OCC23CCN(CC2)CC3)c(-c2ccccc2)s1>>Cl.N#Cc1nc(NC(=O)OCC23CCN(CC2)CC3)c(-c2ccccc2)s1,,CCOC(C)=O,CN(C)C=O,O=P(Cl)(Cl)Cl,O=C([O-])O.[Na+],test
US06960586B2,CC(C)C(=O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.CN1Cc2c(ccc3cc(Br)ccc23)C1=O>>CC(C)C(O)(c1ccc2c3c(ccc2c1)C(=O)N(C)C3)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US04979978,Cc1ccc(O)c(Cc2ccccc2O)c1.O=C(O)C(Cl)Cl>>Cc1cccc2c1Cc1ccccc1OC(C(=O)O)O2,,CC(C)O,,[I-].[K+],,test
US20090197908A1,CC[Mg]Cl.O=Cc1ccc2ccc3ncc(Cl)cc3c(=O)c2c1>>CCC(O)c1ccc2ccc3ncc(Cl)cc3c(=O)c2c1,,ClCCl,,,,test
US05491148,COc1cccc2c(=O)n([C@@H]3CN4CCC3CC4)ccc12>>COc1cccc2c1CCN([C@@H]1CN3CCC1CC3)C2=O,,O,,,,test
US20110086854A1,CN.O=Cc1cccc(Cl)c1F>>C/N=C/c1cccc(Cl)c1F,,ClCCl,,,,test
US20050277643A1,CC(=O)N1CC(C)(C)c2ccc(Nc3ncnc4c3CCN(c3ncccc3Cl)C4)cc21>>CC1(C)CNc2cc(Nc3ncnc4c3CCN(c3ncccc3Cl)C4)ccc21,,CCO,,Cl,,test
US20080269288A1,NC1CCCCC1.O=C(O)c1ccc(Cl)nc1Cl>>O=C(NC1CCCCC1)c1ccc(Cl)nc1Cl,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20070082912A1,CC#N.CC(=O)CCC(=O)c1cc(F)ccc1OCc1ccc(F)cc1.COC(=O)c1cc(N)ccc1OC(F)F.Cc1ccc(S(=O)(=O)O)cc1.ClCCl>>CCCC(C)C.CCOC(C)=O.COC(=O)c1cc(-n2c(C)ccc2-c2cc(F)ccc2OCc2ccc(F)cc2)ccc1OC(F)F,,CC#N,ClCCl,Cl,,test
US20040067966A1,CCCn1c(=O)c2[nH]c(C34CCC(O)(CC3)CC4)nc2n(CCC)c1=O.CS(=O)(=O)Cl>>CCCn1c(=O)c2[nH]c(C34CCC(OS(C)(=O)=O)(CC3)CC4)nc2n(CCC)c1=O,,ClCCl,,CCN(CC)CC,,test
US20120165382A1,CC(C)(C)OC(=O)NN.O=Cc1cc(Cl)ccc1O>>CC(C)(C)OC(=O)NNCc1cc(Cl)ccc1O,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100331326A1,CC(C)(O)c1ccncc1Br.O=C1NCCN1c1ccc2ncsc2c1>>CC(C)(O)c1ccncc1N1CCN(c2ccc3ncsc3c2)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20140275030A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.Cc1noc(C)c1-c1ccc2[nH]c(=O)n3c2c1OCC3c1ccccn1>>Cc1noc(C)c1-c1ccc2[nH]c(=S)n3c2c1OCC3c1ccccn1,,C1COCCO1,,,,test
US03960828,CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CSCc1ccccc1)C(=O)NCC(N)=O.NC(=O)C[C@H](NC(=O)OCc1ccccc1)C(=O)Oc1ccc([N+](=O)[O-])cc1>>CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CSCc1ccccc1)NC(=O)[C@@H](N)CC(N)=O)C(=O)NCC(N)=O,,CCOC(C)=O,,CN(C)C=O,,test
US06579883B1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C1Nc2c(F)cccc2C2CCCC12F>>Fc1cccc2c1NC(=S)C1(F)CCCC21,,C1CCOC1,,,,test
US06300368B1,CCN(CC)CCOc1ccc(N)cc1.COc1cccc(OC)c1C(=O)Cl>>CCN(CC)CCOc1ccc(NC(=O)c2c(OC)cccc2OC)cc1,,c1ccncc1,,,,test
US20100305133A1,CCOC(=O)CNC(=O)c1c(O)ccc2nc(Br)cnc12.OB(O)c1cccnc1>>CCOC(=O)CNC(=O)c1c(O)ccc2nc(-c3cccnc3)cnc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20130261102A1,Cc1ccc(S(=O)(=O)Cl)cc1.[O-][n+]1cccc2ncc(I)cc21>>O=c1ccc2ncc(I)cc2[nH]1,,ClC(Cl)Cl,O,O=C([O-])[O-].[K+].[K+],,test
US20090176786A1,CN(C(=O)C(F)(F)F)c1ccc(SSc2ccc(N(C)C(=O)C(F)(F)F)cc2)cc1>>CNc1ccc(SSc2ccc(NC)cc2)cc1,,CO,,[H-].[Na+],O=C([O-])[O-].[K+].[K+],test
US06177440B1,COC(=O)COc1cccc2c1c1c(C(N)=O)cccc1n2Cc1ccccc1Cc1ccccc1>>NC(=O)c1cccc2c1c1c(OCC(=O)O)cccc1n2Cc1ccccc1Cc1ccccc1,,CCO,,[Na+].[OH-],,test
US20090124807A1,CCOC(CBr)OCC.CCOC(CC(C(=O)OC)C(=O)OC)OCC>>CCOC(CC(CC(OCC)OCC)(C(=O)OC)C(=O)OC)OCC,,CN(C)C=O,,CC(C)(C)O[K],,test
US05189043,CC(C)N.CCOC(=O)/C=C/CBr>>CCOC(=O)/C=C/CNC(C)C,,CCO,,CCN(CC)CC,,test
US20090137642A1,CI.O=C(Cc1nn[nH]n1)c1ccccc1>>Cn1nnnc1CC(=O)c1ccccc1,,CC(C)=O,,,,test
US20140329799A1,FC(F)(F)c1ccc2sc(S)nc2c1>>FC(F)(F)c1ccc2scnc2c1,[Fe],CC(=O)O,,,,test
US20070219235A1,CCO.NN.O=Cc1cc([N+](=O)[O-])ccc1Cl>>O=[N+]([O-])c1ccc2c(cnn2CCO)c1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,,test
US20020035266A1,CC(=O)OC(C)=O.Nc1ccc(Br)cc1C(F)(F)F>>CC(=O)Nc1ccc(Br)cc1C(F)(F)F,,C1CCOC1,,,,test
US20090253687A1,COc1cccc(N(N)C(=O)OC(C)(C)C)c1>>COc1cccc(NN)c1,,ClCCl,O,O=C(O)C(F)(F)F,,test
US20120046269A1,COC(=O)c1cccc2c(=O)nc[nH]c12.O=C1CCC(=O)N1I>>COC(=O)c1cc(I)cc2c(=O)nc[nH]c12,,O=S(=O)(O)O,,O=C([O-])[O-].[K+].[K+],,test
US20050038050A1,COc1ccc(Cl)c(Nc2ncnc3cc(O)cc(OCCCN4CCOCC4)c23)c1.OCCCN1CCOCC1>>COc1ccc(Cl)c(Nc2ncnc3cc(OCCCN4CCOCC4)cc(OCCCN4CCOCC4)c23)c1,,ClCCl,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160130299A1,CC(C)(C)OC(=O)N1C(=O)[C@@H](CCO)C[C@@H]1Cc1ccc([N+](=O)[O-])cc1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1C(=O)[C@@H](CCOS(C)(=O)=O)C[C@@H]1Cc1ccc([N+](=O)[O-])cc1,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,,test
US20150065465A1,COc1ccc(CN(c2nc(Cl)nn3c(C#N)cnc23)C2CC2)cc1.N#Cc1ncc(Cl)c(N)n1>>COc1ccc(CN(c2nc(Nc3nc(C#N)ncc3Cl)nn3c(C#N)cnc23)C2CC2)cc1,,C1COCCO1,CCOC(C)=O,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20130237501A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(c3ccc([N+](=O)[O-])c(Cl)c3)S(C)(=O)=O)c(C3CC3)cc12.COC(=O)CC(=O)OC>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(c3ccc([N+](=O)[O-])c(C(C(=O)OC)C(=O)OC)c3)S(C)(=O)=O)c(C3CC3)cc12,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090143381A1,CC(C)(C)OC(=O)c1cccc(B(O)O)c1.O=C(Nc1cc2ccccc2c(Br)n1)C1(c2ccc3c(c2)OC(F)(F)O3)CC1>>CC(C)(C)OC(=O)c1cccc(-c2nc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)cc3ccccc23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US20150133451A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cn1ccc(N)n1.O=C=NCCCl>>Cn1ccc(N2CCN(C(=O)OC(C)(C)C)C2=O)n1,CN(C)c1ccncc1,C1CCOC1,CCN(CC)CC,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US04720506,CCOC(=O)C(C)(C(=O)OCC)c1ccc([N+](=O)[O-])cc1>>CC(C(=O)O)c1ccc([N+](=O)[O-])cc1,,CCO,O,[Na+].[OH-],,test
US04097491,CC1CCOC(CBr)O1.CCCOC(CN)OCCC>>CCCOC(CNCC1OCCC(C)O1)OCCC,,Cc1ccccc1,,CCN(CC)CC,,test
US20050164989A1,CNP(=O)(NC)N1CCC[C@H](NC(=O)OCc2ccccc2)C1=O>>CNP(=O)(NC)N1CCC[C@H](N)C1=O,[Pd],CO,,,,test
US07612075B2,C=CCOC(=O)N1CC(=O)N(Cc2ccc(C#N)c(N=C(c3ccccc3)c3ccccc3)c2)C(C(=O)OC)C1>>COC(=O)C1CNCC(=O)N1Cc1ccc(C#N)c(N=C(c2ccccc2)c2ccccc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,ClCCl,,C1COCCN1,,test
US20020147230A1,CC(C)(C)O.Nc1cccnc1.O=C=NS(=O)(=O)Cl>>CC(C)(C)OC(=O)NS(=O)(=O)Nc1cccnc1,,ClCCl,,CCN(CC)CC,,test
US20040019023A1,C[C@@H](OCCC(=O)N(C)C)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>C[C@@H](OCCC(=O)N(C)C)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040082625A1,C[C@@H](N)c1ccccc1.Cc1ccc(C(=O)Cl)cc1Br>>Cc1ccc(C(=O)N[C@H](C)c2ccccc2)cc1Br,,ClCCl,,O=C([O-])O.[Na+],,test
US20100298336A1,BrP(Br)Br.CC(C)c1ncsc1CO>>CC(C)c1ncsc1CBr,,ClCCl,,,,test
US20060058264A1,COC(=O)[C@@H]1C[C@H](N)C(=O)[C@@H]2[C@@]3(C)C[C@@H](c4ccoc4)OC(=O)[C@@H]3CC[C@]21C.CS(=O)(=O)Cl>>COC(=O)[C@@H]1C[C@H](NS(C)(=O)=O)C(=O)[C@@H]2[C@@]3(C)C[C@@H](c4ccoc4)OC(=O)[C@@H]3CC[C@]21C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US05286869,COC(=O)C1=C(C)NC(C)=C(C(=O)O)C1c1cccc([N+](=O)[O-])c1.OC/C=C/c1cccc(Cc2ncc[nH]2)n1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OC/C=C/c2cccc(Cc3ncc[nH]3)n2)C1c1cccc([N+](=O)[O-])c1,,Cc1ccccc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05386011,COC(=O)[C@H](N)Cc1ccccc1.Cl>>COC(=O)[C@H](N)CC1CCCCC1.Cl,[Rh],CO,,,,test
US20110160198A1,COC(=O)[C@H](Cc1ccc2c(c1)OC[C@H](c1ccc(OCc3ccc(Cl)c(Cl)c3)cc1)O2)NC(=O)OC(C)(C)C>>COC(=O)[C@H](Cc1ccc2c(c1)OC[C@H](c1ccc(O)cc1)O2)NC(=O)OC(C)(C)C,[Pd],CCOC(C)=O,CO,,,test
US20060004078A1,CC1(C)COC(C=Cc2ccc([N+](=O)[O-])cc2)OC1>>CC1(C)COC(CCc2ccc(N)cc2)OC1,[Pd],CO,,,,test
US06765014B1,CCN=C=NCCCN(C)C.O=C([O-])Cc1ccc2c(c1)CCN2>>COC(=O)Cc1ccc2c(c1)CCN2,CN(C)c1ccncc1,CC#N,,CCOCC,,test
US06251911B1,CC(C)(C)C(=O)OC(=O)C(C)(C)C.Nc1n[nH]c2ncnc(Nc3cccc(Cl)c3)c12>>CC(C)(C)C(=O)Nc1n[nH]c2ncnc(Nc3cccc(Cl)c3)c12,,ClCCl,c1ccncc1,,,test
US05866589,CCNC1CCN(Cc2ccccc2)CC1.O=[N+]([O-])c1ccc(F)nc1F>>CCN(c1nc(F)ccc1[N+](=O)[O-])C1CCN(Cc2ccccc2)CC1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20130217666A1,CCOC(=O)c1nc2c([nH]1)C1CC(C1)c1cc(F)c(I)cc1-2.Cn1nccc1CCl>>CCOC(=O)c1nc2c(n1Cc1ccnn1C)C1CC(C1)c1cc(F)c(I)cc1-2,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US04410529,CC1(C)CC1C(=O)Cl.Nc1ccc(C2=NNC(=O)CC2)cc1>>CC1(C)CC1C(=O)Nc1ccc(C2=NNC(=O)CC2)cc1,,C1CCOC1,,,,test
US20140107094A1,CCOC(=O)c1ccc2nc(C)c(Cc3ccccc3)c(C)c2c1.CNOC>>CON(C)C(=O)c1ccc2nc(C)c(Cc3ccccc3)c(C)c2c1,,C1CCOC1,,CC(C)[Mg]Cl,Cl,test
US20030220324A1,CC(C)(C)OC(=O)N1CCN(c2ccccc2NS(C)(=O)=O)CC1.CI>>CN(c1ccccc1N1CCN(C(=O)OC(C)(C)C)CC1)S(C)(=O)=O,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20060036031A1,CCCC=O.NCc1ccccc1>>CCCC=NCc1ccccc1,,Cc1ccccc1,,,,test
US04034088,CC(=O)OCC1=C(C(=O)OC(C)(C)C)N2C(=O)C(NC(=O)Cn3ccnc3S(C)(=O)=O)C2SC1>>CC(=O)OCC1=C(C(=O)O)N2C(=O)C(NC(=O)Cn3ccnc3S(C)(=O)=O)C2SC1,,O=C(O)C(F)(F)F,,,,test
US20030078251A1,CC(=O)Cl.COc1cccc([C@H]2O[C@H](CC(=O)Nc3ccc(CCC(=O)O)cc3C)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC>>COc1cccc([C@H]2O[C@H](CC(=O)Nc3ccc(CCC(=O)O)cc3C)C(=O)N(CC(C)(C)COC(C)=O)c3ccc(Cl)cc32)c1OC,,O,,CCOC(C)=O,c1ccncc1,test
US20150126490A1,CC(C)(C)OC(=O)N1C[C@@H](c2ccc(N)nc2)C[C@H]1CO.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N1C[C@@H](c2cnc(N)c(Br)c2)C[C@H]1CO,,CC#N,CCOC(C)=O,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20090018180A1,CSC1=NCCN1.I.NCc1ccc(Cl)c(Cl)c1>>Clc1ccc(CNC2=NCCN2)cc1Cl.I,,CO,,,,test
US04698337,Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(NC(=O)C(=NOCC#N)c3csc(NC=O)n3)[C@H]2SC1>>Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(NC(=O)C(=NOCC#N)c3csc(N)n3)[C@H]2SC1,,C1CCOC1,CO,Cl,,test
US20100094000A1,Cc1c(B2OC(C)(C)C(C)(C)O2)ccc2c1NC(=O)CO2.Cc1nn(CC(F)(F)COCc2ccccc2)c(-c2ccc(F)cc2)c1Br>>Cc1nn(CC(F)(F)COCc2ccccc2)c(-c2ccc(F)cc2)c1-c1ccc2c(c1C)NC(=O)CO2,,COCCOC,,O,[K],test
US20120010182A1,COc1ccc(CN(c2nncs2)S(=O)(=O)c2cc(Cl)c(Oc3ccc(-c4ccc(C(F)(F)F)nc4)cc3-c3ccnnc3)cc2F)c(OC)c1>>O=S(=O)(Nc1nncs1)c1cc(Cl)c(Oc2ccc(-c3ccc(C(F)(F)F)nc3)cc2-c2ccnnc2)cc1F,,Cl,,C1COCCO1,,test
US20050197350A1,CCOC(=O)[C@@H]1CC[C@H](Nc2nc(C)cc(N(C)C)n2)CC1>>Cc1cc(N(C)C)nc(N[C@H]2CC[C@@H](C(=O)O)CC2)n1,,CCO,O,Cl,[K+].[OH-],test
US20120208798A1,CC(=O)N1c2ccc(-c3nc(CNC(=O)OC(C)(C)C)no3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C.Cl>>CC(=O)N1c2ccc(-c3nc(CN)no3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C.Cl,,C1COCCO1,,,,test
US20140057909A1,CC(C)NNC(=O)c1ccccc1.O=C(O)/C=C/c1c[nH]c2ccccc12>>CC(C)N(NC(=O)c1ccccc1)C(=O)/C=C/c1c[nH]c2ccccc12,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150051395A1,CC(C)(C)OC(=O)N[C@@H](CO)C(=O)OC1CCCCC1.II>>CC(C)(C)OC(=O)N[C@@H](CI)C(=O)OC1CCCCC1,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020072533A1,CCCC[C@@H](C)C[C@H](CO)CC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)Cl)cc1>>CCCC[C@@H](C)C[C@H](COS(=O)(=O)c1ccc(C)cc1)CC(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20030109532A1,CCCI.C[C@@H]1CNCC[C@@H]1c1cccc(S(C)(=O)=O)c1>>CCCN1CC[C@H](c2cccc(S(C)(=O)=O)c2)[C@H](C)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20050085508A1,Cc1ccc(NC2CCN(CC3CCCCC3)CC2)nc1.O=C(Cl)c1ccco1>>Cc1ccc(N(C(=O)c2ccco2)C2CCN(CC3CCCCC3)CC2)nc1,,ClCCl,,CCN(CC)CC,,test
US20100144825A1,CN(CCN(CCCN)c1cccc(Cl)c1)C(=O)OC(C)(C)C.COC(=O)Cl>>COC(=O)NCCCN(CCN(C)C(=O)OC(C)(C)C)c1cccc(Cl)c1,,ClCCl,,CCN(CC)CC,O,test
US20100113462A1,CCOC(=O)C1(NC(=O)c2cccc3c2CCCC3=O)Cc2ccccc2C1>>O=C1CCCc2c1cccc2C(=O)NC1(C(=O)O)Cc2ccccc2C1,,CCO,,O,[K+].[OH-],test
US20120172382A1,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.Nc1cc(F)c(Oc2ncncc2I)cc1F>>Cn1cc(-c2cncnc2Oc2cc(F)c(N)cc2F)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160194302A1,CC(=O)OC(C)=O.Cn1ccnc1CCC(=O)N1CCC(N)CC1>>CC(=O)NC1CCN(C(=O)CCc2nccn2C)CC1,,ClCCl,,c1ccncc1,,test
US20090270412A1,CCOC(CCCNC)OCC.Cc1ccc(N(N)CCC2CCCCC2)cc1>>CNCCc1cn(CCC2CCCCC2)c2ccc(C)cc12,,Cl,O,CCO,,test
US04249015,OC(C1C=CCCC1)C(Cl)(Cl)Cl>>OC(C1CCCCC1)C(Cl)(Cl)Cl,O=[Pt]=O,CO,,[H][H],,test
US20050085476A1,COC(=O)Cc1n[nH]c(=O)c2c1CCCC2>>O=c1[nH]nc(CCO)c2c1CCCC2,,C1CCOC1,,Cl,[BH4-].[Na+],test
US20090197862A1,COC(=O)C(OC)OC.NCc1cc(Cl)ccc1F>>COC(OC)C(=O)NCc1cc(Cl)ccc1F,,CCCCCCC,,,,test
US20060241127A1,Cc1n[nH]c2cccc(O)c12.O=[N+]([O-])c1ccc(F)c(F)c1>>Cc1n[nH]c2cccc(Oc3ccc([N+](=O)[O-])cc3F)c12,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20060204985A1,CC(=O)O.CCN(CC)CC>>CC(=O)[O-].CC[NH+](CC)CC,,O,,,,test
US20080171761A1,CCOC(=O)c1cc(OC)c2c(C)cn(C3CC3)c2c1>>COc1cc(C(=O)O)cc2c1c(C)cn2C1CC1,,CO,,Cl,[Na+].[OH-],test
US04778790,CC(C)(C)OC(=O)CN1C[C@@H](c2cccs2)SC[C@H](N)C1=O.CCOC(=O)C(Br)CCCCCCCNC(=O)OC(C)(C)C>>CCOC(=O)[C@@H](CCCCCCCNC(=O)OC(C)(C)C)N[C@H]1CS[C@H](c2cccs2)CN(CC(=O)OC(C)(C)C)C1=O,,CCOC(C)=O,,c1ccccc1,,test
US05457104,CC1C=CC(N)C2CNCC12.CCn1cc(C(=O)O)c(=O)c2ccc(F)c(Cl)c21>>CCn1cc(C(=O)O)c(=O)c2ccc(N3CC4C(C)C=CC(N)C4C3)c(Cl)c21,,CS(C)=O,,C1CN2CCN1CC2,,test
US20090182025A1,CC(F)(F)c1ccc(-c2cc(N)sn2)cc1.C[C@@H]1C[C@H]1C(=O)OCc1ccccc1>>C[C@@H]1C[C@H]1C(=O)Nc1cc(-c2ccc(C(C)(F)F)cc2)ns1,,O=C([O-])O,[Na+],CC(C)(C)[O-].[K+],,test
US20070249670A1,COC(=O)c1sc(-c2ccc(OC)cc2)cc1N>>COc1ccc(-c2cc(N)c(C(=O)O)s2)cc1,,C1COCCO1,,Cl,[Li+].[OH-],test
US04690707,CN(C)c1ncccc1S(N)(=O)=O.COc1nc(C)nc(N(C(=O)[O-])c2ccccc2)n1>>COc1nc(C)nc(NC(=O)NS(=O)(=O)c2cccnc2N(C)C)n1,,C1COCCO1,,,,test
US04908357,C1=Cc2ccccc2SC1.CC(=O)Cl>>CC(=O)C1C=Cc2ccccc2S1,,ClC(Cl)(Cl)Cl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20020107234A1,CC(=O)Cl.O=C(O)CCCCC(S)CCS>>CC(=O)SCCC(S)CCCCC(=O)O,,ClCCl,,CCN(CC)CC,,test
US20090156578A1,COC(=O)C(C)(C)COc1cccnc1[N+](=O)[O-]>>COC(=O)C(C)(C)COc1cccnc1N,[Pd],CO,,,,test
US20140187545A1,COC(=O)CC(=O)OC.Nc1n[nH]c(N)c1Cc1cccc2ccccc12>>Nc1nn2c(c1Cc1cccc3ccccc13)NC(=O)CC2=O,,CO,,C[O-].[Na+],,test
US20140275152A1,CC(=O)N1CCC(c2ccccc2)=C(CO)C1.O=S(Cl)Cl>>CC(=O)N1CCC(c2ccccc2)=C(CCl)C1,,ClCCl,,,,test
US04034088,CCOC(=O)CCl.CSc1ncc[nH]1>>CCOC(=O)Cn1ccnc1SC,,CN(C)C=O,,[H-].[Na+],,test
US20080167378A1,BrCCCc1ccccc1.CCOC(=O)CCc1ccc(O)cc1>>CCOC(=O)CCc1ccc(OCCCc2ccccc2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20110288251A1,CC(=O)Cl.CC(=O)OC1CC(C)(C)N(OC(=NC2CCCCC2)NC2CCCCC2)C(C)(C)C1>>CC(=O)OC1CC(C)(C)N(OC(=NC2CCCCC2)N(C(C)=O)C2CCCCC2)C(C)(C)C1,,Cc1ccccc1,,CCN(CC)CC,,test
US20150132352A1,C=CCn1c(=S)[nH]c2c(c1=O)C(C)(C)Cc1cnccc1-2.COCCOS(=O)(=O)c1ccc(C)cc1>>C=CCn1c(SCCOC)nc2c(c1=O)C(C)(C)Cc1cnccc1-2,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06506764B1,C1CC2(CCN1)OCCO2.CC(C)C(CS(=O)(=O)Cl)C(=O)OC(C)(C)C>>CC(C)C(CS(=O)(=O)N1CCC2(CC1)OCCO2)C(=O)OC(C)(C)C,,CCN(CC)CC,,ClCCl,,test
US20160016935A1,COc1ccnc(O[C@@H]2CC[C@@H](C)N(C(=O)OCc3ccccc3)C2)c1>>COc1ccnc(O[C@@H]2CC[C@@H](C)NC2)c1,[Pd],CO,,,,test
US05229516,CCC1(CC(=O)OC)OCCc2c1[nH]c1ccc(OCc3ccccc3)cc21>>CCC1(CC(=O)O)OCCc2c1[nH]c1ccc(OCc3ccccc3)cc21,,O,,CO,[K+].[OH-],test
US20060183911A1,COc1ncc(-c2ccnc(SC)n2)cc1NC(=O)c1ccc(C(C)(C)C)cc1>>CSc1nccc(-c2c[nH]c(=O)c(NC(=O)c3ccc(C(C)(C)C)cc3)c2)n1,,C1COCCO1,O,,,test
US20130079478A1,C1CCOC1.CCN(CC)CC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.c1ccc(Nc2ccccc2)cc1>>O=C(N(c1ccccc1)c1ccccc1)N(c1ccccc1)c1ccccc1,,C1CCOC1,,,,test
US20110306771A1,C=CCOCCOCC(=O)OC>>C=CCOCCOCCO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120064181A1,CO.Nc1c(Br)cc(C(=O)O)cc1[N+](=O)[O-]>>COC(=O)c1cc(Br)c(N)c([N+](=O)[O-])c1,,CO,ClCCl,C[Si](C)(C)C=[N+]=[N-],,test
US20150175561A1,C#CC[C@H](NC(=O)OC(C)(C)C)C(=O)NC(=N)SC.NN>>C#CC[C@H](NC(=O)OC(C)(C)C)c1nc(N)n[nH]1,,CCO,,O,,test
US20090163586A1,C=CCN(CC=C)S(=O)(=O)c1cnccc1N.O=S(=O)(Cl)c1cccc(Br)c1>>C=CCN(CC=C)S(=O)(=O)c1cnccc1NS(=O)(=O)c1cccc(Br)c1,,C1CCOC1,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US05162312,COc1ccc2c(c1)CC[C@H]1[C@@H]3CCC(=O)[C@@]3(C)CC[C@H]21.C[Si](C)(C)Cl>>COc1ccc2c(c1)CC[C@H]1[C@@H]3CC=C(O[Si](C)(C)C)[C@@]3(C)CC[C@H]21,,CC#N,,CCN(CC)CC,[I-].[Na+],test
US20080221148A1,COCCOCCO.O=Cc1cc(F)c(F)cc1Cl>>COCCOCCOc1cc(Cl)c(C=O)cc1F,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100168418A1,COc1cc(Br)c2ccc(=O)n(CCN3CCC(N(Cc4ccc5c(c4)OCCO5)C(=O)OC(C)(C)C)CC3)c2c1>>COc1ccc2ccc(=O)n(CCN3CCC(NCc4ccc5c(c4)OCCO5)CC3)c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110136763A1,BrB(Br)Br.CCOC(=O)CC1OB(O)c2cc(OC3CCCCO3)cc(COC)c21>>CCOC(=O)CC1OB(O)c2cc(O)cc(CBr)c21,,ClCCl,,CCO,,test
US05089504,CCC(=O)c1cnc2c(OC)cccc2c1Cl>>CCC(=O)c1cnc2c(O)cccc2c1Cl,,ClCCl,,BrB(Br)Br,,test
US20040002524A1,COc1ccc(-n2c(-c3c(C)noc3C)nc3ccccc32)c(C)c1>>Cc1cc(O)ccc1-n1c(-c2c(C)noc2C)nc2ccccc21,,ClCCl,,BrB(Br)Br,,test
US20160108016A1,CI.COc1cc(CC(=O)N2C(=O)OC[C@@H]2C(C)C)cc(OC)c1>>COc1cc(OC)cc([C@H](C)C(=O)N2C(=O)OC[C@@H]2C(C)C)c1,,C1CCOC1,,CCCCCC,,test
US20090325942A1,CCOC(=O)c1ccc2c(c1)S(=O)(=O)c1ccc(C(CC3CCC(=O)C3)C(=O)Nc3ccn(C)n3)cc1N2C>>CN1c2cc(C(CC3CCC(=O)C3)C(=O)Nc3ccn(C)n3)ccc2S(=O)(=O)c2cc(C(=O)O)ccc21,,CO,,[Na+].[OH-],,test
US20110070317A1,CC(C)(C)OC(=O)N[C@@H]1CCCNC1.COC1(C(=O)Nc2c[nH]c3ncc(Br)c(F)c23)CC1>>COC1(C(=O)Nc2c[nH]c3ncc(Br)c(N4CCC[C@@H](NC(=O)OC(C)(C)C)C4)c23)CC1,,CCCCO,O,CC#N,,test
US05866589,CC=O.CCN(c1ncccc1N)C1CCN(Cc2ccccc2)CC1>>CCNc1cccnc1N(CC)C1CCN(Cc2ccccc2)CC1,,CCOC(C)=O,CO,O,[BH3-]C#N.[Na+],test
US04188485,C1CC2OCCOC2CN1.O=C(Cl)C(c1ccccc1)c1ccccc1>>O=C(C(c1ccccc1)c1ccccc1)N1CCC2OCCOC2C1,,c1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US05714489,CC(=O)O.CCOC(=O)Cn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(N)cc21.COC1CCC(OC)O1>>CCOC(=O)Cn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(-n3cccc3)cc21,,CC(=O)O,,,,test
US20150368247A1,C[C@H]1CC[C@H](Cn2cnc3nc(C(=O)NN)nc(N[C@H](C)C4CCC4)c32)CC1.O=C(n1ccnc1)n1ccnc1>>C[C@H]1CC[C@H](Cn2cnc3nc(-c4n[nH]c(=O)o4)nc(N[C@H](C)C4CCC4)c32)CC1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20020132794A1,O=C(O)[C@@H]1C[C@@H]1c1cccc([N+](=O)[O-])c1>>Nc1cccc([C@H]2C[C@H]2C(=O)O)c1,O=[Pt]=O,CCO,,,,test
US20020156081A1,COc1cc(-c2nn(-c3ccc(C=O)cc3)c3ncnc(N)c23)ccc1NC(=O)c1ccc(C(F)(F)F)cc1F.O[C@@H]1CCNC1>>COc1cc(-c2nn(-c3ccc(CN4CC[C@@H](O)C4)cc3)c3ncnc(N)c23)ccc1NC(=O)c1ccc(C(F)(F)F)cc1F,,CC(Cl)Cl,,[Na+].[OH-],,test
US20110152253A1,C1CCOC1.CS(=O)(=O)Cl.O=C1CCOc2cc(F)ccc21>>C=CC1(Cl)CCOc2cc(F)ccc21,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20080207695A1,CC1=C(CC(=O)O)C(=O)N(NCC(F)(F)c2ccccn2)CC1.Cc1cc(N)nc(CO)c1CN>>CC1=C(CC(=O)NCc2c(C)cc(N)nc2CO)C(=O)N(NCC(F)(F)c2ccccn2)CC1,,CN(C)C=O,,CCN(CC)CC,ClCCCl,test
US20110015238A1,CCCC[C@H](C)C[C@@H](/C=C/[C@H]1CC[C@H](OC(C)=O)[C@@H]1CCCCCC([Se]c1ccccc1)C(=O)OC)OC1CCCCO1>>CCCC[C@H](C)C[C@@H](/C=C/[C@H]1CC[C@H](O)[C@@H]1CCCCCC([Se]c1ccccc1)C(=O)OC)OC1CCCCO1,,CCOC(C)=O,CO,O=C([O-])[O-].[K+].[K+],,test
US20100204226A1,CCOC(=O)NC(=Nc1ccc(Br)cc1)n1cc(C(=O)OCC)cn1>>CCOC(=O)c1cnn(-c2nc3ccc(Br)cc3c(=O)[nH]2)c1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,ClCCCl,,test
US06211234B1,CCOC(=O)CCC(Oc1cc(OCc2ccsc2)ccc1C(N)=O)c1ccccc1C.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)CCC(Oc1cc(OCc2ccsc2)ccc1C(N)=S)c1ccccc1C,,C1CCOC1,,,,test
US20100197682A1,COc1ccc(B(O)O)cn1.O=C(Nc1cn2cc(Br)ccc2n1)C(F)(F)F>>COc1ccc(-c2ccc3nc(N)cn3c2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100093730A1,O=C(O)CN1CCC(c2ccccc2)(c2ccccc2)C1=O.OC(c1cccc(C(F)(F)F)c1)(c1cccc(C(F)(F)F)c1)C1CCNCC1>>O=C(CN1CCC(c2ccccc2)(c2ccccc2)C1=O)N1CCC(C(O)(c2cccc(C(F)(F)F)c2)c2cccc(C(F)(F)F)c2)CC1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20100048537A1,CI.OC1CNCc2sccc21>>CN1Cc2sccc2C(O)C1,,CN(C)C=O,,O,O=C([O-])[O-].[Na+].[Na+],test
US20090306078A1,N#Cc1cccc(N)c1.O=C(O)COc1ccc(C23CC4CC(CC(C4)C2)C3)cc1>>N#Cc1cccc(CC(N)=O)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,On1nnc2ccccc21,test
US20140031364A1,COC(=O)c1c(-c2cccc(F)c2)noc1C>>Cc1onc(-c2cccc(F)c2)c1C(=O)O,,CO,,[Na+].[OH-],,test
US20090239854A1,CCN1CCc2[nH]c3ccc(C)cc3c2C1.Cc1ccc(CCl)cn1>>CCN1CCc2c(c3cc(C)ccc3n2Cc2ccc(C)nc2)C1,,CN(C)C=O,,[H-].[Na+],,test
US20090214444A1,CC(C)(C)OC(=O)NCCCOc1ccc(C=CCCN=[N+]=[N-])c2ccccc12>>CC(C)(C)OC(=O)NCCCOc1ccc(CCCCN)c2ccccc12,[Pd],CCO,,,,test
US20130225524A1,CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(-c4ccnc(C)c4)ccc23)c1>>Cc1cc(-c2ccc3c(Nc4cccc(C(=O)O)c4)c(C(N)=O)cnc3c2)ccn1,,CCO,,[Na+].[OH-],,test
US03962443,CCOS(=O)(=O)OCC.O=C(O)c1c[nH]c2nc(N3CCNCC3)ncc2c1=O>>CCn1cc(C(=O)O)c(=O)c2cnc(N3CCNCC3)nc21,,CC(=O)O,,O=C([O-])[O-].[Na+].[Na+],,test
US20100075948A1,CC(C)(C)C/C=N/CC(=O)OC(C)(C)C.COc1cc(Cl)ccc1/C(C#N)=C/c1cccc(Cl)c1F>>COc1cc(Cl)ccc1C1(C#N)C(CC(C)(C)C)NC(C(=O)OC(C)(C)C)C1c1cccc(Cl)c1F,,ClCCl,,CCN(CC)CC,,test
US20080300242A1,COc1cc(N2CCC(N3CCNC(=O)C3)CC2)ccc1[N+](=O)[O-].FCCI>>COc1cc(N2CCC(N3CCN(CCF)C(=O)C3)CC2)ccc1[N+](=O)[O-],,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20110098296A1,CC(N)=S.O=C(Cc1ccnc(Cl)n1)c1cccc(NC(=O)c2cc(F)ccc2F)c1>>Cc1nc(-c2cccc(NC(=O)c3cc(F)ccc3F)c2)c(-c2ccnc(Cl)n2)s1,,CN(C)C=O,ClCCl,O=C1CCC(=O)N1Br,,test
US20100093654A1,CCc1ccc(Cc2cc(C3(O)O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)cc(B3OC(C)(C)C(C)(C)O3)c2C)cc1.OO>>CCc1ccc(Cc2cc(C3(O)O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)cc(O)c2C)cc1,,CC(=O)O,,CCOC(C)=O,O,test
US20100298285A1,CC(C)(C)OC(=O)N1CCc2c(ccc(Cl)c2NC(=O)Cc2ccc(C(F)(F)F)cc2)C1.Cl>>Cl.O=C(Cc1ccc(C(F)(F)F)cc1)Nc1c(Cl)ccc2c1CCNC2,,CCOCC,,ClCCl,,test
US20070249670A1,COC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(OC)c(F)c2)cc1N)[C@@H](C)OC(C)(C)C.Cc1cc(C)c(N=C=O)c(C)c1>>COC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(OC)c(F)c2)cc1NC(=O)Nc1c(C)cc(C)cc1C)[C@@H](C)OC(C)(C)C,,c1ccncc1,,CCCCCC,CCOC(C)=O,test
US20050026989A1,COc1ccc2c(C(=O)O)cn(-c3ccnc4ccccc34)c2c1.O=S(Cl)Cl>>COc1ccc2c(C(=O)Cl)cn(-c3ccnc4ccccc34)c2c1,CN(C)C=O,,,,,test
US05332739,CN.O=S(=O)(Cl)c1ccc(OCCCBr)cc1>>CNS(=O)(=O)c1ccc(OCCCBr)cc1,,O,,,,test
US04278791,CCOC(=O)CCCP(=O)(OCC)OCC.Nc1ccccc1N>>O=P(O)(O)CCCc1nc2ccccc2[nH]1,,Cl,,O,,test
US20050277630A1,CCCC(=O)OC[C@H]1CN(c2ccc3c(c2)CCC(N=[N+]=[N-])C(=O)N3)C(=O)O1>>CCCC(=O)OC[C@H]1CN(c2ccc3c(c2)CCC(N)C(=O)N3)C(=O)O1,[Pd],CCOC(C)=O,,,,test
US20090221851A1,CC(=O)N/C(=C\C[PH](=O)CO)C(=O)O>>CC(=O)N[C@@H](CC[PH](=O)CO)C(=O)O,,CO,,[H][H],,test
US20120041009A1,NC(=NO)c1cc(C(F)(F)F)nc(C(F)(F)F)n1.O=C(n1ccnc1)n1ccnc1>>O=c1nc(-c2cc(C(F)(F)F)nc(C(F)(F)F)n2)[nH]o1,,C1CCOC1,O,C1CCC2=NCCCN2CC1,Cl,test
US20040186113A1,CC(C)(C)OC(=O)Nc1cnccc1CCN1CCCC1>>Nc1cnccc1CCN1CCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150329549A1,C=CC[Sn](CCCC)(CCCC)CCCC.Nc1ccc(OC(F)(F)F)cc1Br>>C=CCc1cc(OC(F)(F)F)ccc1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,CN(C)C=O,[F-].[K+],,test
US20080146607A1,CC(C)(C)OC(=O)N1CCC(Cc2ccccc2)(C(=O)c2ccc3[nH]cc(C#N)c3c2)C1>>N#Cc1c[nH]c2ccc(C(=O)C3(Cc4ccccc4)CCNC3)cc12,,CO,,Cl,,test
US20090143448A1,Cn1ccc2cccc(O)c21.OCCI>>Cn1ccc2cccc(OCCO)c21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080064676A1,COc1ccc(C2(CS[C@H]3C(=O)N(c4ccc(F)cc4)[C@@H]3c3ccc(OCC(=O)OC(C)(C)C)cc3)OCC(C)(C)CO2)cc1>>COc1ccc(C(=O)CS[C@H]2C(=O)N(c3ccc(F)cc3)[C@@H]2c2ccc(OCC(=O)O)cc2)cc1,,O=CO,,,,test
US20130331375A1,CCn1ccc2c(=O)[nH]c(Cl)cc21.OB(O)c1ccc(C(F)(F)F)cc1>>Cn1ccc2c(=O)[nH]c(-c3ccc(C(F)(F)F)cc3)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20080269286A1,CC(C)(C)OC(=O)N1CCC(O)(c2ccc(Cl)c(C(F)(F)F)c2)CC1>>FC(F)(F)c1cc(C2=CCNCC2)ccc1Cl,,O=C(O)C(F)(F)F,,,,test
US20070244095A1,COC(=O)c1cccc(CN2CCC[C@H](N(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)c3nnn(C)n3)c3cc(C)c(C(F)(F)F)cc32)c1>>Cc1cc2c(cc1C(F)(F)F)N(Cc1cccc(C(=O)O)c1)CCC[C@@H]2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1,,CO,,Cl,[Na+].[OH-],test
US20070179165A1,CCCNCCC.COc1cccc2nc(Cl)n(C)c(=O)c12>>CCCN(CCC)c1nc2cccc(OC)c2c(=O)n1C,,C1CCOC1,O,,,test
US20110008259A1,CCOC(=O)c1c[nH]c2cc(CC)cn2c1=O>>CCc1cc2[nH]cc(C(=O)O)c(=O)n2c1,,CO,,[Na+].[OH-],,test
US20100234346A1,CCc1cc(C(=O)NCC(=O)c2cc(C)nc(NC(C)C)n2)cc(C)c1OCc1ccccc1>>CCc1cc(-c2ncc(-c3cc(C)nc(NC(C)C)n3)o2)cc(C)c1OCc1ccccc1,,C1CCOC1,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US05665329,CCOC(=O)Cn1ccnc1[N+](=O)[O-]>>O=C(O)Cn1ccnc1[N+](=O)[O-],,[Na+],[OH-],,,test
US20100234344A1,Cc1cc(-c2ccnn2C)c2cccc(OCc3c(Cl)cncc3CCl)c2n1.N>>Cc1cc(-c2ccnn2C)c2cccc(OCc3c(Cl)cncc3CN)c2n1,,CCO,,,,test
US20100210641A1,Clc1ccn2c(-c3ccnc(Cl)c3)cnc2c1.OB(O)c1ccccc1>>Clc1ccn2c(-c3ccnc(-c4ccccc4)c3)cnc2c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US20110071175A1,Fc1ccc(S)cc1.O=Cc1ccc(Br)cc1>>O=Cc1ccc(Sc2ccc(F)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04438128,NCCNc1cccc2cn[nH]c12.c1ccc(OCC2CO2)cc1>>OC(CNCCNc1cccc2cn[nH]c12)COc1ccccc1,,CC(C)O,,,,test
USH0002007H1,Cc1[nH]c2ccccc2c1CC(=O)Cl.Fc1ccc(C(c2ccc(F)cc2)N2CCNCC2)cc1>>Cc1[nH]c2ccccc2c1CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1,,C1CCOC1,CCOC(C)=O,c1ccncc1,O=C([O-])O.[Na+],test
US20140187533A1,CSCC(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1N>>CSCc1nc2c(C(F)(F)F)cc(C(F)(F)F)cc2[nH]1,,C1CCOC1,,CC(=O)O,,test
US20060025438A1,CC(C)(C)OC(=O)NCC(=O)NCc1cc(F)cc(C(F)(F)F)c1.O=C(O)C(F)(F)F>>NCC(=O)NCc1cc(F)cc(C(F)(F)F)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20140357858A1,Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1.O=S(=O)(Cl)c1cccnc1>>O=C1CC(=O)N(c2ccc(NS(=O)(=O)c3cccnc3)cc2)c2ccc3ccccc3c2N1,,c1ccncc1,,,,test
US20060270856A1,NS(N)(=O)=O.c1ccc(C2CCNCC2)cc1>>NS(=O)(=O)N1CCC(c2ccccc2)CC1,,C1COCCO1,,,,test
US20100016354A1,CC(C)(C)OC(=O)Nc1cc(CSc2ncccc2-c2nnc(Nc3ccccc3)o2)ccn1.Cl>>Cl.Nc1cc(CSc2ncccc2-c2nnc(Nc3ccccc3)o2)ccn1,,C1COCCO1,,,,test
US20020147334A1,CCOC(=O)CN(Cc1ccccc1)Cc1ccc(OCCc2cccc(N(C)C(=O)OC(C)(C)C)n2)cc1>>CNc1cccc(CCOc2ccc(CN(CC(=O)O)Cc3ccccc3)cc2)n1,,C1COCCO1,Cl,,,test
US06337196B1,CC(=O)OC(C)=O.CO.c1ccncc1>>CCC[C@@](C)(C#N)OC(C)=O,,ClCCl,,,,test
US20110152240A1,CC(C)(C)OC(=O)N1CCC(N)CC1.Clc1cc(Cl)n2nccc2n1>>CC(C)(C)OC(=O)N1CCC(Nc2cc(Cl)nc3ccnn23)CC1,,O,,CC#N,CCN(CC)CC,test
US05409886,CC(=O)C(C)N(C(=O)Cc1ccccc1)C(C)(C)c1cc(Cl)cc(Cl)c1>>CC1=C(c2ccccc2)C(=O)N(C(C)(C)c2cc(Cl)cc(Cl)c2)C1C,,O,,Cc1ccccc1,,test
US20110201815A1,CC1Cc2cc(Br)ccc2N1.CI>>CC1Cc2cc(Br)ccc2N1C,,CN(C)C=O,,O,[H-].[Na+],test
US20080027065A1,CCOC(=O)c1ccc(Oc2ccc(F)cc2)nc1>>O=C(O)c1ccc(Oc2ccc(F)cc2)nc1,,C1COCCO1,O,Cl,[Li+].[OH-],test
US04102878,CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)NCC(=O)O.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl>>CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)NCC(=O)Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20060074075A1,CCC(C)Br.O=[N+]([O-])c1ccc2cc[nH]c2c1>>CCC(C)c1c[nH]c2cc(N)ccc12,,CC#N,,,,test
US20160207949A1,C=C1C[C@H]2C=Nc3cc(OCCP(=O)(CCS)CCOc4cc5c(cc4OC)C(=O)N4CC(=C)C[C@H]4CN5)c(OC)cc3C(=O)N2C1.CC(C)(CCC(=O)ON1C(=O)CCC1=O)SSc1ccc([N+](=O)[O-])cn1>>C=C1C[C@H]2C=Nc3cc(OCCP(=O)(CCOc4cc5c(cc4OC)C(=O)N4CC(=C)C[C@H]4CN5)CCSSC(C)(C)CCC(=O)ON4C(=O)CCC4=O)c(OC)cc3C(=O)N2C1,,CC(=O)N(C)C,,,,test
US20150005315A1,COc1ccc(C)cc1Oc1ccc(C(=O)O)cc1>>Cc1ccc(O)c(Oc2ccc(C(=O)O)cc2)c1,,Br,,,,test
US20140349972A1,CCOP(=O)(OCC)c1ccc([C@H](C)NC(=O)c2cnc(-c3ccccn3)nc2O)cc1>>C[C@H](NC(=O)c1cnc(-c2ccccn2)nc1O)c1ccc(P(=O)(O)O)cc1,,ClCCl,,C[Si](C)(C)Br,,test
US20150218173A1,CCc1[nH]c2ncnc(Cl)c2c1C.Nc1ccc2[nH]ncc2c1>>CCc1[nH]c2ncnc(Nc3ccc4[nH]ncc4c3)c2c1C,,CCO,CCOCC,Cl,,test
US04927970,CCCCOc1c(NCCCO)c(=O)c1=O.CS(=O)(=O)Cl>>CCCCOc1c(NCCCS(C)(=O)=O)c(=O)c1=O,,c1ccncc1,,O,,test
US20130123323A1,Cc1nn(C)c(C(O)c2ccc(F)cc2F)c1-c1ccc(F)cc1Cl.O=S(Cl)Cl>>Cc1nn(C)c(C(Cl)c2ccc(F)cc2F)c1-c1ccc(F)cc1Cl,,ClCCl,,CCN(CC)CC,,test
US20080167293A1,COc1ccc2c(c1)C(=O)N1C[C@@H](O)C(OCCCCCOC3[C@H]4[C@H](O[Si](C)(C)C(C)(C)C)N(C(=O)OCC(Cl)(Cl)Cl)c5ccc(OC)cc5C(=O)N4C[C@H]3O)[C@H]1[C@H](O[Si](C)(C)C(C)(C)C)N2C(=O)OCC(Cl)(Cl)Cl>>COc1ccc2c(c1)C(=O)N1CC(=O)C(OCCCCCOC3C(=O)CN4C(=O)c5cc(OC)ccc5N(C(=O)OCC(Cl)(Cl)Cl)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]34)[C@H]1[C@H](O[Si](C)(C)C(C)(C)C)N2C(=O)OCC(Cl)(Cl)Cl,,ClCCl,,,,test
US20040116435A1,CC1(COc2ccccc2NC(=O)C(F)(F)F)CO1.O=c1[nH]c2ccccc2n1C1CCNCC1>>CC(O)(COc1ccccc1N)CN1CCC(n2c(=O)[nH]c3ccccc32)CC1,,CCO,,[NH4+].[OH-],,test
US04954518,CC(=O)Nc1cc2c(cc1Oc1ccccc1)C(=O)CCO2>>Nc1cc2c(cc1Oc1ccccc1)C(=O)CCO2,,CCO,,Cl,,test
US05234946,BrP(Br)Br.OCc1cccc(C#Cc2ccccc2)c1>>BrCc1cccc(C#Cc2ccccc2)c1,,ClC(Cl)Cl,,O,,test
US20080234255A1,CCCCNCCC(=O)OC(C)(C)C.O=[N+]([O-])c1cnc(Cl)nc1Cl>>CCCCN(CCC(=O)OC(C)(C)C)c1nc(Cl)ncc1[N+](=O)[O-],,CCOCC,O,O=C([O-])O.[K+],,test
US20120208814A1,CC(=O)N1c2ccc(-c3cnn(CCN(C)C(=O)OC(C)(C)C)c3)cc2[C@H](Nc2ccncc2)C[C@@H]1C>>CNCCn1cc(-c2ccc3c(c2)[C@H](Nc2ccncc2)C[C@H](C)N3C(C)=O)cn1.O=CO,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080004309A1,CCOC(=O)c1nc(C#N)c2c(c(Br)cn2Cc2ccccc2)c1OC(C)=O.C[Sn](C)(C)C>>CCOC(=O)c1nc(C#N)c2c(c(C)cn2Cc2ccccc2)c1OC(C)=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,,,test
US20130059835A1,COc1c(C(C)n2nc(C(F)F)c3c(N)ncnc32)cc(C#N)c(C)c1C1CN(C(=O)OC(C)(C)C)C1.Cl.ClCCl>>COc1c(C(C)n2nc(C(F)F)c3c(N)ncnc32)cc(C#N)c(C)c1C1CNC1.Cl.Cl,,ClCCl,,C1COCCO1,,test
US20060211698A1,COC(=O)c1ccc2c(C3CCCCC3)c(-c3cc([N+](=O)[O-])c4nc(-c5sc(C)nc5C)ccc4c3)n(CC(=O)N3CCOCC3)c2c1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3cc(N)c4nc(-c5sc(C)nc5C)ccc4c3)n(CC(=O)N3CCOCC3)c2c1,[Pd],CN(C)C=O,CO,,,test
US20020002187A1,CC(=O)OC(C)=O.Cc1sc2cc3ccccc3c(-c3ccc(O)c(C4CCCC4)c3)c2c1C>>CC(=O)Oc1ccc(-c2c3ccccc3cc3sc(C)c(C)c23)cc1C1CCCC1,,c1ccncc1,,Cl,,test
US20140350019A1,CC(C)OC(=O)CBr.COc1cc(CNc2c(F)ccc(O)c2C)cc(-c2cccc(F)c2)c1>>COc1cc(CNc2c(F)ccc(OCC(=O)OC(C)C)c2C)cc(-c2cccc(F)c2)c1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US05880162,COC(=O)C(F)=CC(c1ccc(Cl)cc1)C1CC1>>OCC(F)=CC(c1ccc(Cl)cc1)C1CC1,,CCOCC,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US06624199B1,COc1ccc(C(=O)c2ccc(Nc3ccccc3N)cc2Cl)c(Cl)c1>>Nc1ccccc1Nc1ccc(C(=O)c2ccc(O)cc2Cl)c(Cl)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20090137572A1,Cc1nc(C)c(/C=C/C(=O)N(C)C)s1.N=C(N)Nc1cc(Cl)c(N2CCOCC2)c(Cl)c1>>Cc1nc(C)c(-c2ccnc(Nc3cc(Cl)c(N4CCOCC4)c(Cl)c3)n2)s1,,CC#N,,,,test
US20150232428A1,CS(=O)(=O)N1CCN(c2cc(N)cc(-c3ccccc3)c2)CC1.FC(F)(F)c1ccnc(Cl)n1>>CS(=O)(=O)N1CCN(c2cc(Nc3nccc(C(F)(F)F)n3)cc(-c3ccccc3)c2)CC1,,C1COCCO1,CCOC(C)=O,Cc1ccc(S(=O)(=O)O)cc1,,test
US05077288,CCOC(=O)CC(C)=O.O=C(c1ccc(F)cc1)C1CCN(CCCl)CC1>>CCOC(=O)C(CCN1CCC(C(=O)c2ccc(F)cc2)CC1)C(C)=O,,C1CCOC1,,[H-].[Na+],,test
US20160200704A1,COC(=O)c1ccc2nc(S(C)(=O)=O)ccc2c1>>CS(=O)(=O)c1ccc2cc(CO)ccc2n1,,C1CCOC1,,,,test
US20150368252A1,CC=O.COC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C>>COC(=O)C1(C(C)O)CCCN1C(=O)OC(C)(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20120270865A2,CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2cn(-c3cccc(OC)c3)nc2CC)C2CCCCC2)cc1.CI>>CCOC(=O)CCN(C)C(=O)c1ccc(N(C)C(c2cn(-c3cccc(OC)c3)nc2CC)C2CCCCC2)cc1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20020183319A1,Cc1cc(C(=O)N2CC(C)NC(C)C2)[nH]c1C=O.O=C1Cc2c(ncnc2Nc2ccc(F)c(Cl)c2)N1>>Cc1cc(C(=O)N2CC(C)NC(C)C2)[nH]c1C=C1C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c21,C1CCNCC1,CCO,,,,test
US20100105642A1,CC(C)(C)C=O.CCOC(CN)OCC>>CCOC(CNCC(C)(C)C)OCC,,ClCCl,O,O=C([O-])O.[Na+],,test
US04874775,CC(C)S(=O)(=O)Cl.Clc1ccc(NCc2cccnc2)cc1>>CC(C)S(=O)(=O)N(Cc1cccnc1)c1ccc(Cl)cc1,,ClC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US20050245563A1,Cc1[nH]nc2c1c(=O)[nH]c1c(OCCCNC(=O)OC(C)(C)C)cccc12>>Cc1[nH]nc2c1c(=O)[nH]c1c(OCCCN)cccc12,,C1COCCO1,,Cl,,test
US20160075713A1,CCOC(=O)C(F)(F)c1ncc(Cl)cc1F>>OCC(F)(F)c1ncc(Cl)cc1F,,CCO,,[BH4-].[Na+],,test
US20030220368A1,COc1ncccc1CCl.OCC1CCNCC1>>COc1ncccc1CN1CCC(CO)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05500474,Nc1ccccc1.O=S(=O)([O-])CCCCCBr.[Na+]>>O=S(=O)([O-])CCCCCNc1ccccc1.[Na+],,O,,O=C([O-])O.[K+],,test
US04447361,Nc1ccccc1C(=O)c1ccc(Cl)cc1.Nc1cccnc1Cl>>Clc1ccc(C2=Nc3cccnc3Nc3ccccc32)cc1,,ClCCl,,,,test
US04027023,CCc1ccc2nnc(C(=O)O)cc2c1.Oc1ccccc1>>CCc1ccc2nnc(C(=O)Oc3ccccc3)cc2c1,,C1CCOC1,,O=S(Cl)Cl,,test
US20160016951A1,Cc1cc(N)c(Br)cn1.II>>Cc1ncc(Br)c(N)c1I,,CCOC(C)=O,O,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US20150238473A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCCCN1CCC(C(O)(c2ccccc2)c2ccccc2)CC1>>Cc1ccc(S(=O)(=O)OCCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1,,ClCCl,,,,test
US04016262,CC(=O)N1CN(C(C)=O)C2C(=C1Cl)N(C(C)=O)CN2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O.CC=CCNC>>CC=CCN(C)c1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O,,CC(C)O,,CCN(CC)CC,,test
US20110172216A1,CC1(C)OB(c2n[nH]c3ccccc23)OC1(C)C.COc1cccc(Oc2nc(Cl)nc3c2cnn3C)c1>>COc1cccc(Oc2nc(-c3cccc4[nH]ncc34)nc3c2cnn3C)c1,,O,,,,test
US20110312935A1,CNc1ccc(C(=O)Nc2cccc(Cl)n2)cc1[N+](=O)[O-]>>CNc1ccc(C(=O)Nc2cccc(Cl)n2)cc1N,[Fe],CCO,,[Cl-].[NH4+],,test
US20120238549A1,COC(=O)c1ccc2c(c1)CC[C@H]1CC3(CC[C@@]21Cc1ccccc1)OCCO3>>COC(=O)c1ccc2c(c1)CC[C@H]1CC(=O)CC[C@@]21Cc1ccccc1,,ClCCl,,O,,test
US05273991,CN(C)NC(=O)c1nc(N)cn1C.Cn1cc([N+](=O)[O-])nc1C(=O)Cl>>CN(C)NC(=O)c1nc(NC(=O)c2nc([N+](=O)[O-])cn2C)cn1C,,C1CCOC1,ClCCl,,,test
US20120029190A1,Fc1ccc(-c2nc3c(o2)CCNC3)cc1.O=C(O)c1ccc(F)cc1>>O=C(c1ccc(F)cc1)N1CCc2oc(-c3ccc(F)cc3)nc2C1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20110183953A1,CC(C)Oc1ccc(-c2nnc(-c3cccc4c3CC[C@@H]4NC(=O)OC(C)(C)C)s2)cc1C#N.Cl>>CC(C)Oc1ccc(-c2nnc(-c3cccc4c3CC[C@@H]4N)s2)cc1C#N.Cl,,C1COCCO1,CCOCC,,,test
US20030065179A1,CC(=O)O[C@H](C)c1nccc(N2CCN(Cc3ccccn3)CC2)n1>>C[C@@H](O)c1nccc(N2CCN(Cc3ccccn3)CC2)n1,,C1COCCO1,CCOC(C)=O,[K+].[OH-],,test
US20100197619A1,C=O.O=c1cc(-c2ccccc2)oc2cc(O)c(O)c(O)c12.OC1CCNC1>>O=c1cc(-c2ccccc2)oc2c(CN3CCC(O)C3)c(O)c(O)c(O)c12,,CO,,,,test
US20090312338A1,C[Si](C)(C)C#Cc1nc(Br)cnc1N.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)n2ccc3nc(Br)cnc32)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20030225283A1,COC(=O)C(CC1CCCC1OC1CCCCO1)c1ccc(Cl)c(Cl)c1>>COC(=O)C(CC1CCCC1O)c1ccc(Cl)c(Cl)c1,,CCO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20070265289A1,CI.Nc1nc(-c2ccccc2O)cc(C2CCCNC2)n1>>CN1CCCC(c2cc(-c3ccccc3O)nc(N)n2)C1,,CC#N,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20130230542A1,CCN(CCO)c1ccccc1.O=S(Cl)Cl>>CCN(CCCl)c1ccccc1,,ClCCl,,,,test
US20040259903A1,COc1cc2c(cc1OC)C1CC(NC(=O)OC(C)(C)C)C(C(=O)O)CN1CC2.C[Si](C)(C)CCO.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COc1cc2c(cc1OC)C1CC(NC(=O)OC(C)(C)C)C(NC(=O)OCC[Si](C)(C)C)CN1CC2,,Cc1ccccc1,,CCN(CC)CC,,test
US20130172341A1,COC(=O)C1CNCC(C)C1.O=Cc1ccccc1F>>COC(=O)C1CC(C)CN(Cc2ccccc2F)C1,CC(=O)O,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130143892A1,C=C(OC)C(=O)[O-].ClCCl.N#Cc1ccc(C=NOCl)c(F)c1>>COC(=O)C1(OC)CC(c2ccc(C#N)cc2F)=NO1,,ClCCl,,CCN(CC)CC,O,test
US20050054536A1,CCC(CSC)C(=O)Cl.CCCOC(=O)CC#N>>CCCOC(=O)C(C#N)=C(O)C(CC)CSC,,ClCCl,,CCN(CC)CC,,test
US20020156081A1,C=O.c1ccc2[nH]cnc2c1>>OCn1cnc2ccccc21,,C1CCOC1,,,,test
US20160002215A1,CCOc1cc(OCc2ccc(OC)cc2)ncc1-c1ccc(CC(=O)Nc2cnc(C(C)(C)C(F)(F)F)cc2Br)c(F)c1.ClCCl>>CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2ccc(C(C)(C)C(F)(F)F)nc2)c(F)c1.Cl,[Pd],,,,,test
US20160222030A1,Fc1ccc2nc(Cl)sc2c1.NC1CC(F)(F)CC1NC(=O)c1ccccc1-n1nccn1>>O=C(NC1CC(F)(F)CC1Nc1nc2ccc(F)cc2s1)c1ccccc1-n1nccn1,,CS(C)=O,,CCN(C(C)C)C(C)C,Cl,test
US20030176698A1,C1CCNC1.CCCN1C(=O)N2C[C@@H](Cc3ccccc3)N=C2c2c1nc(Br)n2Cc1ccccc1>>CCCN1C(=O)N2C[C@@H](Cc3ccccc3)N=C2c2c1nc(N1CCCC1)n2Cc1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150266881A1,CC(C)(C)O.COC(=O)c1ccc([C@@H]2C[C@H]2C(=O)O)cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COC(=O)c1ccc([C@@H]2C[C@H]2NC(=O)OC(C)(C)C)cc1,,Cc1ccccc1,,CCN(CC)CC,[Cl-].[NH4+],test
US05374641,CO.Cc1ccc(CC(=O)O)cc1>>COC(=O)Cc1ccc(C)cc1,,CO,,Cl,,test
US20160244437A1,COCCOCCOCCN.Cc1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)cc1-c1cccc(C(=O)O)c1>>COCCOCCOCCNC(=O)c1cccc(-c2cc(C[C@H](NC(=O)[C@@H]3CC[C@@H](CNC(=O)OC(C)(C)C)CC3)C(=O)Nc3ccc(-c4nnn[nH]4)cc3)ccc2C)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090131444A1,COC(=O)[C@@H]1CC[C@@H](N=[N+]=[N-])CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1CC[C@@H](N)CN1C(=O)OC(C)(C)C,[Pd],CO,,,,test
US20090163471A1,C=O.NC(=O)c1ccc(C2CCNCC2)cc1>>CN1CCC(c2ccc(C(N)=O)cc2)CC1,,CO,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140206681A1,CCOC(=O)c1ccnc(C(N)=O)c1>>CCOC(=O)C1CCNC(C(N)=O)C1,O=[Pt]=O,CO,,Cl,,test
US20140057937A1,FC(F)(F)c1n[nH]c2c1COCC2.O=C(CCl)N1CCCc2c1cnn2-c1ccc(F)cc1>>O=C(Cn1nc(C(F)(F)F)c2c1CCOC2)N1CCCc2c1cnn2-c1ccc(F)cc1,,C1CCOC1,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20140234254A1,Brc1ccn2nccc2c1.COc1ncc(B2OC(C)(C)C(C)(C)O2)cc1NS(=O)(=O)c1ccc(F)cc1F>>COc1ncc(-c2ccn3nccc3c2)cc1NS(=O)(=O)c1ccc(F)cc1F,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150266825A1,CC(C)(C)OC(=O)NC1CCNCC1.CC(C)(F)COS(=O)(=O)C(F)(F)F>>CC(C)(F)CN1CCC(NC(=O)OC(C)(C)C)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100137612A1,O=C(CC(O)(c1cc(Cl)cc(Cl)c1)C(F)(F)F)c1ccc(Br)nc1>>O=C(C=C(c1cc(Cl)cc(Cl)c1)C(F)(F)F)c1ccc(Br)nc1,,Cc1ccccc1,,O=S(Cl)Cl,c1ccncc1,test
US20120129830A1,C=C1CN(C(=O)OC(C)(C)C)C1.O=C(Cl)C(Cl)(Cl)Cl>>CC(C)(C)OC(=O)N1CC2(CC(=O)C2(Cl)Cl)C1,[Zn],CCOCC,,COCCOC,,test
US20150175602A1,CC(C)Nc1nc2c(nc1N1CCC(Oc3ccc(F)cc3F)CC1)CNCC2.CS(=O)(=O)Cl.O=C(O)C(F)(F)F>>CC(C)Nc1nc2c(nc1N1CCC(Oc3ccc(F)cc3F)CC1)CN(S(C)(=O)=O)CC2.O=C(O)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20150038528A1,CCOC(=O)C(C)(C)CNC(=O)c1nc(C#N)c2cc(NC(=O)Nc3ccccc3)ccc2c1O>>CC(C)(CNC(=O)c1nc(C#N)c2cc(NC(=O)Nc3ccccc3)ccc2c1O)C(=O)O,,CO,,[Na+].[OH-],,test
US20150152108A1,CC1(C)OC[C@@H](COc2ccnc(NC(=O)N3c4nc(-c5cccc(C(F)(F)F)c5)ccc4N4CC[C@H]3C4)c2)O1>>O=C(Nc1cc(OC[C@@H](O)CO)ccn1)N1c2nc(-c3cccc(C(F)(F)F)c3)ccc2N2CC[C@H]1C2,,ClCCl,O,C1COCCO1,Cl,test
US04853404,CCOCn1nccc1C(=O)c1ccc(OCC(=O)OCC)c(Cl)c1Cl>>CCOCn1nccc1C(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl,,CCO,,[Na+].[OH-],,test
US05912258,CC(C)=CCC/C(C)=C/COc1ccc(C(=O)O)cc1.CCCSc1nnc(N)s1>>CCCSc1nnc(NC(=O)c2ccc(OC/C=C(\C)CCC=C(C)C)cc2)s1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,[H-].[Na+],test
US04064239,O=[N+]([O-])c1cccc(C(F)(Cl)C(F)(Cl)Cl)c1>>Nc1cccc(C(F)(Cl)C(F)(Cl)Cl)c1,,CCO,,Cl,,test
US20040254378A1,CC(C)=CCCl.Oc1cccnc1Br>>CC(C)=CCOc1cccnc1Br,,CN(C)C=O,,O,[H-].[Na+],test
US20160185779A1,O=C(Nc1cccc(Cl)c1)Oc1ccccc1.c1csc(-c2n[nH]c3c2CNCC3)n1>>O=C(Nc1cccc(Cl)c1)N1CCc2[nH]nc(-c3nccs3)c2C1,,ClCCl,,,,test
US20090069384A1,CCCC[Sn](CCCC)(CCCC)c1cc(C)cs1.CCOC(=O)c1cc2sc(Br)cc2n1Cc1cccc(Br)c1>>CCOC(=O)c1cc2sc(-c3cc(C)cs3)cc2n1Cc1cccc(Br)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20080096861A1,CN(Cc1nc2ccccc2n1Cc1ccc(C#N)cc1)C1CCCc2cccnc21>>CN(Cc1nc2ccccc2n1Cc1ccc(CN)cc1)C1CCCc2cccnc21,[Ni],CO,N,,,test
US05332820,Cc1ccc2cc3ccccc3cc2c1.O=C1CCC(=O)N1Br>>BrCc1ccc2cc3ccccc3cc2c1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US04806547,c1ccc(CN2CCc3ccccc3C2CN2CCCC2)cc1>>c1ccc2c(c1)CCNC2CN1CCCC1,[Pd],CCO,,,,test
US20120202785A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)Nc1cc(F)ccc1Nc1ccccc1>>C[C@H](NC(=O)OC(C)(C)C)c1nc2cc(F)ccc2n1-c1ccccc1,,CC(=O)O,,,,test
US20070010556A1,CCOC(=O)[C@H](C#N)NC(=O)c1ccccc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)c1nc(-c2ccccc2)sc1N,,CCOC(C)=O,Cc1ccccc1,,,test
US05130424,CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3C=CC4=C(N)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C.O=CO>>CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3C=CC4=C(NC=O)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,O,CC(=O)OC(C)=O,,test
US08431695B2,CC(C)(C)OC(=O)N1C=C(c2ccc3c(N)ncnn23)CCC1>>CC(C)(C)OC(=O)N1CCCC(c2ccc3c(N)ncnn23)C1,O=[Pt]=O,CC(=O)O,,,,test
US20040110945A1,CCOC(=O)Cc1cc(Cl)c(N)cc1F.Cn1cc(C(=O)O)c2cc(F)ccc21>>CCOC(=O)Cc1cc(Cl)c(NC(=O)c2cn(C)c3ccc(F)cc23)cc1F,,Cl,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20050256158A1,CCOC(=O)[C@H](F)Oc1ccc(C(=O)N2c3ccccc3[C@H](N(C(C)=O)c3ccc(Cl)cc3)CC2C)cc1>>CC(=O)N(c1ccc(Cl)cc1)[C@@H]1CC(C)N(C(=O)c2ccc(O[C@@H](F)C(=O)O)cc2)c2ccccc21,,C1CCOC1,CO,[K+].[OH-],,test
US20080214598A1,COC(=O)C1=C(c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)nc2)CCN(C(=O)OC(C)(C)C)C1>>COC(=O)C1CN(C(=O)OC(C)(C)C)CCC1c1ccc(OCCOc2c(Cl)cc(C)cc2Cl)nc1,,CO,,Cl,,test
US20010051144A1,CC(C)(C)OC(=O)C(N)COCCO.S=C(Oc1ccccn1)Oc1ccccn1>>CC(C)(C)OC(=O)C(N)COCCOC(O)=[SH]c1ccccn1,,ClC(Cl)Cl,,c1ccncc1,,test
US20160229860A1,BrCc1ccccc1.Nc1cc(C#Cc2cnc3ccc(-c4ccc(C(=O)N5CCOCC5)cc4)nn23)c2cc[nH]c2n1>>O=C(c1ccc(-c2ccc3ncc(C#Cc4cc(NCc5ccccc5)nc5[nH]ccc45)n3n2)cc1)N1CCOCC1,,CN(C)C=O,,[H-].[Na+],,test
US20160002188A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(-c3nc4ccccc4o3)cc2)CC1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C(c1ccc(-c2nc3ccccc3o2)cc1)N1CCNCC1,,ClCCl,,,,test
US20120190677A1,C=C(C)C.COC(=O)c1cccc(N)c1.O=Cc1cccc(Br)c1>>COC(=O)c1ccc2c(c1)NC(c1cccc(Br)c1)CC2(C)C,,CC#N,CCOC(C)=O,O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3],,test
US20080039452A1,O=C(OCc1ccccc1)N1CC[C@@H]2[C@H](c3ccc(F)cc3)Nc3ccccc3[C@@H]21>>Fc1ccc([C@@H]2Nc3ccccc3[C@@H]3NCC[C@H]23)cc1,[Pd],CCO,,,,test
US05578620,CC(C)(CO[Si](C)(C)C(C)(C)C)NC(=O)OCc1ccccc1>>CC(C)(N)CO[Si](C)(C)C(C)(C)C,[Pd],CCO,,,,test
US20100331293A1,Cc1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2cc(F)cc(F)c2c1Cl.Nc1cc(N2CCOCC2)cnc1N1CCOCC1>>Cc1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)cnc1N1CCOCC1,,Cc1ccccc1,,,,test
US08889878B2,CC(N)c1ccc(Br)cc1F.CCC(=O)Cl>>CCC(=O)NC(C)c1ccc(Br)cc1F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150282482A1,CC(C)I.COC(=O)c1sc2ccccc2c1O>>COC(=O)c1sc2ccccc2c1OC(C)C,,COC(C)(C)C,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20110059951A1,C[Si](C)(C)CCOCn1ccc2c(-c3cn[nH]c3)ncnc21.N#CC=CCN1CCN(C(=O)c2ccc(C#N)cc2F)C(CO)C1>>N#CCC(CN1CCN(C(=O)c2ccc(C#N)cc2F)C(CO)C1)n1cc(-c2ncnc3[nH]ccc23)cn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130217715A1,Nc1cccc(Br)c1F.O=S(=O)(Cl)c1cc(F)ccc1F>>O=S(=O)(Nc1cccc(Br)c1F)c1cc(F)ccc1F,,ClCCl,,c1ccncc1,,test
US04327102,Cl.ClCc1ccccn1.Sc1ccccc1>>Cl.c1ccc(SCc2ccccn2)cc1,,CCO,,[Na],,test
US20120157487A1,Nc1cc(Cl)ccc1SCc1ccccc1.O=S(=O)(Cl)c1cc2ccccc2o1>>O=S(=O)(Nc1cc(Cl)ccc1SCc1ccccc1)c1cc2ccccc2o1,,c1ccncc1,,,,test
US20120157453A1,COC(=O)c1c(F)ccc([N+](=O)[O-])c1OC>>COC(=O)c1c(F)ccc(N)c1OC,[Pd],,,CO,,test
US05151545,CCCC[Sn](/C=C\OCC)(CCCC)CCCC.O=CC=Cc1cccc(-c2ccccc2)c1>>O=C/C=C/C=C(c1ccccc1)c1ccccc1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20060217562A1,O=C1CCC(=O)N1O.O=C1Cc2c(C(=O)O)nn(Cc3ccccc3)c2C1>>O=C1Cc2c(C(=O)ON3C(=O)CCC3=O)nn(Cc3ccccc3)c2C1,,ClCCl,,ClCCCl,,test
US20020115674A1,CCn1c(=O)n(OCc2ccccc2)c(=O)c2cc(F)c(F)cc21>>CCn1c(=O)n(O)c(=O)c2cc(F)c(F)cc21,[Pd],C1CCOC1,CO,[H][H],,test
US20030125370A1,CN(C[C@@H]1CCCN1)C1CC1.Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1CC(=O)O>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1CC(=O)N1CCC[C@H]1CN(C)C1CC1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20140371209A1,CCOC(=O)C1CCN(Cc2ccc3cc(OC4CCC(C(C)C)CC4)ccc3c2)CC1>>CC(C)C1CCC(Oc2ccc3cc(CN4CCC(C(=O)O)CC4)ccc3c2)CC1,,CCO,,[Na+].[OH-],,test
US20140275523A1,CC(N)=NNC(C)C.O=C(O)c1c[nH]c(-c2ccc(Cl)cc2F)n1>>CC(=NC(=O)c1c[nH]c(-c2ccc(Cl)cc2F)n1)NNC(C)C,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20070117852A1,CC(=O)C(C)Oc1ccccc1NC(=O)c1cccnc1Cl.NOCc1ccccc1>>CC(=NOCc1ccccc1)C(C)Oc1ccccc1NC(=O)c1cccnc1Cl,,CO,,c1ccncc1,,test
US05834482,ClCCCBr.c1ccc2c(c1)[nH]c1cnc(-c3nc(C4CC4)no3)cc12>>ClCCCn1c2ccccc2c2cc(-c3nc(C4CC4)no3)ncc21,,CN(C)C=O,,[H-].[Na+],,test
US20090197834A1,CCOC(=O)c1cn(C2CCCC2)c2cc(F)ccc2c1=O>>O=C(O)c1cn(C2CCCC2)c2cc(F)ccc2c1=O,,CC(=O)O,,Cl,,test
US20030199547A1,Cn1cncc1C(Cl)(c1ccoc1)c1ccc2c(c1)c(-c1cccc(Cl)c1)cc(=O)n2C.N>>Cn1cncc1C(N)(c1ccoc1)c1ccc2c(c1)c(-c1cccc(Cl)c1)cc(=O)n2C,,C1CCOC1,,CC(C)O,,test
US20010003747A1,CC(=O)OC(C)=O.COc1ccc2c(c1)N(CC#N)CC(c1ccccc1)O2>>COc1ccc2c(c1)N(CCNC(C)=O)CC(c1ccccc1)O2,[Ni],CC(=O)OC(C)=O,,CC(=O)[O-].[Na+],,test
US20140038952A1,CC(C)(C)OC(=O)Nc1ncc(-c2nc(N3CCOCC3)c3ccc(-c4cccc(NC(=O)C(C)(C)O)c4)cc3n2)cn1>>CC(C)(O)C(=O)Nc1cccc(-c2ccc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3c2)c1,,CO,ClCCl,O=C(O)C(F)(F)F,,test
US20100075953A1,CC(=O)Cl.CC(=O)N1CCN(c2ccc(O)cc2)CC1>>CC(=O)Oc1ccc(N2CCN(C(C)=O)CC2)cc1,,ClCCl,,CCN(CC)CC,,test
US20140256733A1,CI.COc1ccc(Nc2ccc3ncc(-c4cc5cc(OC)c(OC)cc5s4)n3n2)cc1OC>>COc1ccc(N(C)c2ccc3ncc(-c4cc5cc(OC)c(OC)cc5s4)n3n2)cc1OC,,CN(C)C=O,,[H-].[Na+],,test
US20130059834A1,II.c1ccn2cncc2c1>>Ic1ncn2ccccc12,,CCO,O,O=C([O-])O.[Na+],,test
US20120052412A1,Fc1ccccc1.O=C(Cl)c1cc(Cl)ccc1Cl>>O=C(c1ccc(F)cc1)c1cc(Cl)ccc1Cl,,O,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US04497813,CC(COc1ccc(O)c(C(N)=O)c1)NCc1ccccc1.COCCOc1ccc(OCC2CO2)cc1>>COCCOc1ccc(OCC(O)CN(Cc2ccccc2)C(C)COc2ccc(O)c(C(N)=O)c2)cc1,,CC(C)O,,,,test
US20130196974A1,CCBr.Oc1ccc2c(c1)CN(c1cc(Cl)c3ccccc3n1)CCC2>>CCOc1ccc2c(c1)CN(c1cc(Cl)c3ccccc3n1)CCC2,,CN(C)C=O,ClCCl,[H-].[Na+],,test
US20160159820A1,COc1ccc(CNCc2c(F)ccnc2NC(=O)OC(C)(C)C)cc1>>COc1ccc(CNCc2c(F)ccnc2N)cc1,,ClCCl,,CO,O=C(O)C(F)(F)F,test
US05506267,CCCCCCCCCCCCCCCCCCNC(=O)OCC(CSCCC(=O)OC(C)(C)C)OC(=O)CCCCCCCCCCCCCCC>>CCCCCCCCCCCCCCCCCCNC(=O)OCC(CSCCC(=O)O)OC(=O)CCCCCCCCCCCCCCC,,O=C(O)C(F)(F)F,,ClCCl,,test
US20100331293A1,COc1ccc(-c2ccc(N3CCOCC3)cc2N)cn1.Cc1c(-c2ccccc2S(C)(=O)=O)nc2cc(F)cc(F)c2c1Cl>>COc1ccc(-c2ccc(N3CCOCC3)cc2Nc2c(C)c(-c3ccccc3S(C)(=O)=O)nc3cc(F)cc(F)c23)cn1,,Cc1ccccc1,,,,test
US20120142735A1,COCCn1ccc2c(Cl)ccc(OC(F)(F)F)c21.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COCCn1cc(C(=O)C(F)(F)F)c2c(Cl)ccc(OC(F)(F)F)c21,,CN(C)C=O,,,,test
US05569664,CCOC(=O)C1CCNCC1.COc1ccc(CCCl)cc1>>CCOC(=O)C1CCN(CCc2ccc(OC)cc2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140329820A1,C#CC(=O)OC.CC(N)=NO>>COC(=O)c1cnc(C)[nH]1,,CO,,,,test
US05872118,CC(CC(=O)O)c1ccc(F)cc1.O=C(Cl)C(=O)Cl>>CC(CC(=O)Cl)c1ccc(F)cc1,,ClCCl,,,,test
US20160229814A1,CCn1c(=O)c2cc(N)ccc2n(CC2CC2)c1=O.O=C1CC[C@H](C(=O)O)O1>>CCn1c(=O)n(CC2CC2)c(=O)c2cc(NC(=O)[C@H]3CCC(=O)O3)ccc21,,CCOC(C)=O,O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US05270327,C1CCN(CC2CSCCN2)C1.O=C1CCC(C(=O)Cl)c2ccc(Cl)cc21>>Cl.O=C1CCC(C(=O)N2CCSCC2CN2CCCC2)c2ccc(Cl)cc21,,CCN(CC)CC,,,,test
US20110263584A1,CC(C)(O)c1cnc(Cl)nc1.C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O>>C[C@@H](c1ccc(-c2ncc(C(C)(C)O)cn2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O=C([O-])O.[Na+],,test
US05126362,Cl.N#CCNc1cccs1.NO>>Cl.NC(CNc1cccs1)=NO,,CO,,,,test
US20100305096A1,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C=O)n(C)c2n1.O=C(C1CNC1)N1CCCC1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CC(C(=O)N4CCCC4)C3)n(C)c2n1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150203515A1,C[Si](C)(C)C1CCC(=O)CC1>>C[Si](C)(C)[C@@H]1CC[C@@H](O)CC1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05530025,CCOc1c(OCC)c(=O)c1=O.CCc1cc(C#N)ccc1N>>CCOc1c(Nc2ccc(C#N)cc2CC)c(=O)c1=O,,CC#N,CCOC(C)=O,,,test
US20070049618A1,NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C(Cl)c1cccc(C(F)(F)F)c1>>O=C1CCC(N2C(=O)c3cccc(CNC(=O)c4cccc(C(F)(F)F)c4)c3C2=O)C(=O)N1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20120071481A1,CCOC(=O)c1noc(-c2ccc(C(F)(F)F)cc2)c1CBr.O>>O=C(O)c1noc(-c2ccc(C(F)(F)F)cc2)c1CO,,O,,O=C(O)C(F)(F)F,,test
US05641789,COC(=O)c1ccc(OC)c(C=O)c1.O=C1CCOc2ccc(OCc3ccccc3)cc21>>COC(=O)c1ccc(OC)c(C=C2COc3ccc(OCc4ccccc4)cc3C2=O)c1,,CO,,C1CCNC1,,test
US05795986,Clc1cc(N2CCCC2)nc(N2CCCC2)n1.NCCO>>OCCNc1cc(N2CCCC2)nc(N2CCCC2)n1,,O,,,,test
US20030073127A1,CC(C)(C)OC(=O)OC(C)(C)C.NCCO>>CC(C)(C)OC(=O)NCCO,,C1COCCO1,,[Na+].[OH-],,test
US03954784,C#CCBr.CC1=CSC2=NCCN12>>C#CCN1CC[n+]2c(C)csc21.[Br-],,CC#N,,,,test
US20160096858A1,CCN(CC)S(F)(F)F.O=C(O[C@@H]1[C@H]2N=C(N3CCC3)S[C@H]2O[C@H](CO)[C@H]1OC(=O)c1ccccc1)c1ccccc1>>O[C@@H]1[C@H]2N=C(N3CCC3)S[C@H]2O[C@H](CF)[C@H]1O,,CC(=O)O,ClCCl,CO,O=C([O-])[O-].[K+].[K+],test
US20100210620A1,CCOC(=O)c1c(SC)cc(OC2CC2)cc1SC>>CSc1cc(OC2CC2)cc(SC)c1C(=O)O,,CO,O,[Li+].[OH-],,test
US20140378461A1,CCOC(=O)[C@H]1[C@@H](c2ccc(Cl)cc2)[C@@H]1C>>CC1C(C(=O)O)C1c1ccc(Cl)cc1,,CO,,[K+].[OH-],,test
US20110275608A1,COC(=O)c1cc(-c2ccccc2)nn1CCNC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCn1nc(-c2ccccc2)cc1CO,,CO,,[BH4-].[Na+],,test
US04288629,CC(C)=O.O=C(O)CCCCCCC(O)C(=O)O>>CC1(C)OC(=O)C(CCCCCCC(=O)O)O1,,O,,O=S(=O)(O)O,O=C([O-])[O-].[Na+].[Na+],test
US20150057279A1,Cc1cccc(Br)[n+]1[O-].O=[N+]([O-])O>>Cc1cc([N+](=O)[O-])cc(Br)[n+]1[O-],,O=S(=O)(O)O,,,,test
US20140018384A1,COC(=O)C(=CNc1cc(OC)ccc1Br)C(=O)c1ccc(F)cc1>>COc1ccc(Br)c2c1C(=O)C(C(=O)c1ccc(F)cc1)C=N2,,CCO,,O=C([O-])O.[Na+],,test
US20030027823A1,CS(=O)(=O)Cl.NCCn1c(=O)[nH]c2ccccc21>>CS(=O)(=O)NCCn1c(=O)[nH]c2ccccc21,,C1CCOC1,,CCN(CC)CC,Cl,test
US05166198,CC(C)(C)[Si](C)(C)Cl.CCOP(=O)(CCC(O)CO)OCC>>CCOP(=O)(CCC(O)CO[Si](C)(C)C(C)(C)C)OCC,,C1CCOC1,CCOCC,c1c[nH]cn1,,test
US20080167314A1,Cc1cccc(-c2nc3cccnn3c2-c2ccnc(N)c2)c1.O=C(Cl)c1ccc(F)cc1>>Cc1cccc(-c2nc3cccnn3c2-c2ccnc(NC(=O)c3ccc(F)cc3)c2)c1,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US07179823B1,CCOC(=O)CCc1c[nH]nc1OCC.ClCc1ccc(OC2CCN(c3ccccn3)CC2)cc1>>CCOC(=O)CCc1cn(Cc2ccc(OC3CCN(c4ccccn4)CC3)cc2)nc1OCC,,O,,CN(C)C=O,[H-].[Na+],test
US20150225452A1,COC(=O)c1ccc(COc2ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)OC)cc2)cc1>>COC(=O)c1ccc(COc2ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)O)cc2)cc1,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20080070894A1,C[C@H](N)c1cccc(N)c1.Fc1cnc(Cl)nc1-c1cnc2c(Cl)cccn12>>C[C@H](Nc1ncc(F)c(-c2cnc3c(Cl)cccn23)n1)c1cccc(N)c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04801605,CCOC(=O)CSc1cccc(OCC)c1CC(=O)OCC>>CCOc1cccc(SCC(=O)O)c1CC(=O)O,,CCO,O,[K+].[OH-],,test
US20030027840A1,CCCCC12Cc3cc(O)ccc3C1=C(C)C(=O)C(CC=O)C2>>CCCCC12Cc3cc(O)ccc3C1=C(C)C(=O)C(CCO)C2,,CC(C)O,,[BH4-].[Na+],,test
US20120196848A1,C[C@H]1CN(C(=O)OC(C)(C)C)Cc2scc(Br)c2O1.OB(O)c1ccccc1F>>C[C@H]1CN(C(=O)OC(C)(C)C)Cc2scc(-c3ccccc3F)c2O1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US04064236,CC(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O.CCOC(=O)[C@](C)(O)C(=O)N(C)N>>CCOC(=O)[C@](C)(O)C(=O)N(C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(C)=O,,C1CCOC1,ClCCl,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20050090534A1,N#CCCc1oc(/C=C/c2ccccc2)nc1-c1ccccc1.O.[OH-]>>O=C(O)CCc1oc(/C=C/c2ccccc2)nc1-c1ccccc1,,CCO,,Cl,,test
US20050277652A1,C=O.CNCCNC(=O)Nc1cc(Oc2ccc(N)cc2F)ncn1>>CN1CCN(C(=O)Nc2cc(Oc3ccc(N)cc3F)ncn2)C1,,C1CCOC1,,,,test
US20120264749A1,CCBr.Cc1cc(C(=O)N2CCC3(CC2)CNC(=O)C(c2ccccc2)O3)ccc1OC(C)C>>CCN1CC2(CCN(C(=O)c3ccc(OC(C)C)c(C)c3)CC2)OC(c2ccccc2)C1=O,,C1CCOC1,,[H-].[Na+],,test
US20120238549A1,CCC[C@@]1(O)CC[C@@]2(CC)c3ccc(C(=O)O)cc3CCC[C@H]2C1.Nc1ccccc1Cl>>CCC[C@@]1(O)CC[C@@]2(CC)c3ccc(C(=O)Nc4ccccc4Cl)cc3CCC[C@H]2C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130172343A1,N#CBr.NC1(c2ncccc2O)c2cc(Br)ccc2Oc2cnc(Cl)cc21>>NC1=NC2(c3cc(Br)ccc3Oc3cnc(Cl)cc32)c2ncccc2O1,,CO,,ClCCl,CC(=O)[O-].[K+],test
US06566394B1,CC(=O)Oc1ccccc1C(=O)Cl.COc1ccc(OC)c(N)c1>>COc1ccc(OC)c(NC(=O)c2ccccc2OC(C)=O)c1,,CCOC(C)=O,c1ccncc1,O,,test
US04435569,CC(C)OCN1C(=O)C2=C(CN)C=NC2=NC1N.O=C1CCCC1>>CC(C)OCN1C(=O)C2=C(CNC3CCCC3)C=NC2=NC1N,,CO,,CC(=O)O,[BH4-].[Na+],test
US20150298887A1,COC(=O)c1ccc2c(c1)CCC(C(=O)OC)C2>>O=C(O)c1ccc2c(c1)CCC(C(=O)O)C2,,CCO,,Cl,[Na+].[OH-],test
US20080167348A1,CS(=O)(=O)c1cc(-c2ccncc2)ccc1NCc1ccccc1>>CS(=O)(=O)c1cc(-c2ccncc2)ccc1N,[Pd],C1COCCO1,CO,Cl,,test
US20120010182A1,COc1ccc(CN(c2nncs2)S(=O)(=O)c2cc(Cl)c(F)cc2F)c(OC)c1.Oc1ccc(-c2ccc(Cl)c(C(F)(F)F)c2)cc1-c1ccnnc1>>COc1ccc(CN(c2nncs2)S(=O)(=O)c2cc(Cl)c(Oc3ccc(-c4ccc(Cl)c(C(F)(F)F)c4)cc3-c3ccnnc3)cc2F)c(OC)c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150018335A1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1c(Cl)cccc1N1CCOCC1>>CC(C)(C)OC(=O)N1CCN(Cc2c(Cl)cccc2N2CCOCC2)CC1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05639766,CCOC(=O)[C@@H]1CCCN(CCON=C2c3ccccc3CCC2c2ccccc2)C1.Cl>>Cl.O=C(O)[C@@H]1CCCN(CCON=C2c3ccccc3CCC2c2ccccc2)C1,,CCO,,ClCCl,[Na+].[OH-],test
US20050171131A1,CC(=O)c1ccc(N)cc1.CCc1nc(N)nc(N)c1-c1ccc(C=O)cc1>>CCc1nc(N)nc(N)c1-c1ccc(CNc2ccc(C(C)=O)cc2)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20110207731A1,C[Si](C)(C)CCOCn1nc(I)c2cc(C=O)ccc21.OCCO>>C[Si](C)(C)CCOCn1nc(I)c2cc(C3OCCO3)ccc21,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20050222118A1,CNc1cc(OC)cc(OC)c1.O=C(Cl)Cl>>COc1cc(CNC(=O)Cl)cc(OC)c1,,Cc1ccccc1,ClCCl,CCN(CC)CC,,test
US20070105890A1,COC(=O)c1[nH]ncc1[N+](=O)[O-].COc1ccc(CCl)cc1>>COC(=O)c1c([N+](=O)[O-])cnn1Cc1ccc(OC)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05773423,Clc1nc(Cl)c2[nH]cnc2n1.NCc1cccc(I)c1>>Clc1nc(NCc2cccc(I)c2)c2[nH]cnc2n1,,CCO,,CCN(CC)CC,Cl,test
US20080188506A1,N#Cc1cccc(C2NC(=O)CC(c3cccc(Cl)c3)C23C(=O)Nc2cc(Cl)ccc23)c1>>N#Cc1cccc(C2NCCC(c3cccc(Cl)c3)C23C(=O)Nc2cc(Cl)ccc23)c1,,CO,,[BH4-].[Na+],,test
US04080443,COc1ccc(Oc2cccc(C(F)(F)F)n2)cc1>>Oc1ccc(Oc2cccc(C(F)(F)F)n2)cc1,,O,,Br,,test
US05583123,O=CCCc1cccc2ccccc12.[O-]P(OCc1ccccc1)OCc1ccccc1>>O=P(OCc1ccccc1)(OCc1ccccc1)C(O)CCc1cccc2ccccc12,,CCOC(C)=O,CN(C)C=O,[F-].[K+],,test
US20080090840A1,CC(C)c1cc(CO)ccc1C(C)(C)C.O=S(Cl)Cl>>CC(C)c1cc(CCl)ccc1C(C)(C)C,,ClCCl,,,,test
US20020016463A1,COc1ccccc1OCC(O)CN(CCNC(=O)OC(C)(C)C)C(=O)CCl>>COc1ccccc1OCC(O)CN1CCNCC1=O,,O=C(O)C(F)(F)F,,CCN(C(C)C)C(C)C,,test
US20100069381A1,COC(=O)c1ccc([N+](=O)[O-])c(F)c1.Nc1cc(C(F)(F)F)ccc1Cl>>COC(=O)c1ccc([N+](=O)[O-])c(Nc2cc(C(F)(F)F)ccc2Cl)c1,,COCCOCCOC,,Cl,[H-].[Na+],test
US20130231328A1,CC(C)(C)OC(=O)NCCc1cc2c(O)ncnc2s1.O=C(O)C(F)(F)F>>NCCc1cc2c(O)ncnc2s1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20020049236A1,COC(=O)Cc1ccc(OS(=O)(=O)C(F)(F)F)cc1.OB(O)c1ccc2ccccc2c1>>COC(=O)Cc1ccc(-c2ccc3ccccc3c2)cc1,,COCCOC,,[Cs+].[F-],,test
US20080214586A1,CCN=C=NCCCN(C)C.CN(C)C=O.CN1CCOCC1.Cl.O=C(O)c1cccc2cc[nH]c12.On1nnc2ccccc21>>Nc1nc(-c2cccc(NC(=O)c3cccc4cc[nH]c34)c2)c2cc(Cl)ccc2n1,,O,,,,test
US20030236298A1,CC(C)(C)[Si](C)(C)Cl.COc1cc(C(C)=O)cc(OC)c1O>>COc1cc(C(C)=O)cc(OC)c1O[Si](C)(C)C(C)(C)C,,CN(C)C=O,,c1c[nH]cn1,,test
US20030187016A1,CCc1nc2c(N)nc3ccccc3c2n1CCOCCN.O=C(Cl)c1ccccc1>>CCc1nc2c(N)nc3ccccc3c2n1CCOCCNC(=O)c1ccccc1,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,O,test
US20110053931A1,CN1CCN(CCCO)CC1.COc1cc2c(Oc3ccc([N+](=O)[O-])cc3F)ccnc2cc1O>>COc1cc2c(Oc3ccc([N+](=O)[O-])cc3F)ccnc2cc1OCCCN1CCN(C)CC1,,ClCCl,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160083376A1,CCOC(=O)CC(=O)N(C)c1c(-c2cccc([N+](=O)[O-])c2)nn(C)c(=O)c1C(=O)OCC>>CCOC(=O)C1C(=O)c2c(c(-c3cccc([N+](=O)[O-])c3)nn(C)c2=O)N(C)C1=O,,CO,,CO[Na],,test
US20140155398A1,CC(C)(C)CC(C)(C)N(C(=O)C1CC1)c1cc2c(ccn2C(=O)C2CC2)cn1>>CC(C)(C)CC(C)(C)N(C(=O)C1CC1)c1cc2[nH]ccc2cn1,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20110130409A1,CC(C)Oc1ccc(CO)cc1C#N.O=S(Cl)Cl>>CC(C)Oc1ccc(CCl)cc1C#N,,Cc1ccccc1,,,,test
US20080132551A1,CCOc1ccc(N)c(Nc2cccnc2)c1.O=C=Nc1nnc(C(F)(F)F)s1>>CCOc1ccc(NC(=O)Nc2nnc(C(F)(F)F)s2)c(Nc2cccnc2)c1,CN(C)c1ccncc1,C1CCOC1,CN(C)C=O,,,test
US06235771B1,CCCCI.OCCOc1ccc(Br)cc1>>CCCCOCCOc1ccc(Br)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US05604004,CC(C)c1ccc(C=O)cc1.NNc1ccccn1>>CC(C)c1ccc(C=NNc2ccccn2)cc1,,CCO,,,,test
US20070060629A1,BrCCOC1CCCCO1.Cc1onc(-c2ccccc2)c1-c1ccc(O)cc1>>Cc1onc(-c2ccccc2)c1-c1ccc(OCCOC2CCCCO2)cc1,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20070259877A1,COc1ccc(N2C[C@H](C)N[C@H](C)C2)cc1N.O=S(=O)(Cl)c1ccc(Cl)nc1>>COc1ccc(N2C[C@H](C)N[C@H](C)C2)cc1NS(=O)(=O)c1ccc(Cl)nc1,,ClCCl,c1ccncc1,Cl,,test
US20150239900A1,Nc1c(C(=O)O)ccc(Br)c1F.OB(O)c1ccc(F)cc1F>>Nc1c(C(=O)O)ccc(-c2ccc(F)cc2F)c1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150329538A1,CC(C)(C)Nc1nc2c(-c3cc4c([nH]3)CCNC4=O)cccc2nc1C=O.COP(=O)(OC)C(=[N+]=[N-])C(C)=O>>C#Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1NC(C)(C)C,,CCOCC,CO,ClCCl,O=C([O-])[O-].[K+].[K+],test
US09199994B2,N#Cc1c(F)cccc1N1CCCCC1.Oc1ccccc1>>N#Cc1c(Oc2ccccc2)cccc1N1CCCCC1,,CN(C)C=O,O,[H-].[Na+],,test
US20110230518A1,N#Cc1ccc2cc(C(=O)O)[nH]c2c1.NO>>NC(=NO)c1ccc2cc(C(=O)O)[nH]c2c1,,CCO,,,,test
US05064840,CC(=O)Cl.Cl.O=C(c1ccncc1)c1nc2ccccc2[nH]1>>Cl.Cl.OC(c1nc2ccccc2[nH]1)C1CCNCC1,[Pt],CCO,,[H][H],,test
US20040204426A1,CC(C)O.CS(=O)c1nccc(-c2cn(Cc3ccccc3C#N)c(=O)n2-c2ccc(F)cc2)n1>>CC(C)Oc1nccc(-c2cn(Cc3ccccc3C#N)c(=O)n2-c2ccc(F)cc2)n1,,CC(C)O,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20060004002A1,CCOc1cc(F)ccc1-c1sc2cncnc2c1C.NN>>CCOc1cc(F)ccc1-c1sc2c(NN)ncnc2c1C,,CCO,,O,,test
US20070249686A1,CC[S-].Fc1ccc(Br)cc1C(F)(F)F>>CCSc1ccc(Br)cc1C(F)(F)F,,CN(C)C=O,,O,,test
US20080306082A1,NCCC1CCN(C(=O)OCc2ccccc2)C1.O=C(NC1CC1)c1cccc2sc(-c3nc(Cl)ncc3Cl)cc12>>O=C(NC1CC1)c1cccc2sc(-c3nc(NCCC4CCN(C(=O)OCc5ccccc5)C4)ncc3Cl)cc12,,C1COCCO1,,CCN(CC)CC,,test
US20070281963A1,COc1cccc(-n2nc3c(c2N)c(=O)[nH]c2cc(O)ccc23)c1.ClCCN1CCOCC1>>COc1cccc(-n2nc3c(c2N)c(=O)[nH]c2cc(OCCN4CCOCC4)ccc23)c1,,CN(C)C=O,O,Cl,[I-].[K+],test
US20030195362A1,CC(C)c1nc(COC(=O)N[C@H](C(=O)O)C(C)C)cs1.N[C@H](Cc1cncs1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1cncs1>>CC(C)c1nc(COC(=O)N[C@H](C(=O)N[C@H](Cc2cncs2)C[C@H](O)[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)C(C)C)cs1,,ClCCl,,CO,,test
US20070149564A1,CCOC(=O)C1(c2cc(-c3ccc(O[Si](C(C)C)(C(C)C)C(C)C)cc3)no2)CC1.O=C1CCC(=O)N1Br>>CCOC(=O)C1(c2onc(-c3ccc(O[Si](C(C)C)(C(C)C)C(C)C)cc3)c2Br)CC1,,CN(C)C=O,,,,test
US20070185092A1,CC(C)OB(OC(C)C)OC(C)C.COc1ccccn1>>COc1ncccc1B(O)O,,C1CCOC1,O,CC(C)NC(C)C,[Li]CCCC,test
US20160166560A1,Br.COc1cc(N2CCC(N(C)C(=O)n3cnc(-c4cccc(OCc5ccccc5)c4)c3)CC2)ccc1Br>>Br.COc1cc(N2CCC(N(C)C(=O)n3cnc(-c4cccc(O)c4)c3)CC2)ccc1Br,,ClCCl,,,,test
US20090215728A1,BrP(Br)Br.OCc1c(Cl)cc(Cl)cc1Br>>Clc1cc(Cl)c(CBr)c(Br)c1,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US05665718,O=C1c2ccccc2C(=O)N1Cc1nnc(-c2ncn3c2[C@@H]2CCCN2C(=O)c2sccc2-3)o1>>NCc1nnc(-c2ncn3c2[C@@H]2CCCN2C(=O)c2sccc2-3)o1,,CCO,,CN,,test
US20080267888A1,CC(C)(C)OC(=O)NC(CO)Cc1ccc(OCc2ccccc2)cc1.Cl>>Cl.NC(CO)Cc1ccc(OCc2ccccc2)cc1,,ClCCl,,,,test
US20090053142A1,C=CCN(C)C(=O)c1c(I)c(N)c(I)c(C(=O)O)c1I.CC(=O)O.CC(=O)O.CC(=O)O.O=C(Cl)[C@@H](O)[C@H](O)CO>>C=CCN(C)C(=O)c1c(I)c(NC(=O)C(OC(C)=O)C(COC(C)=O)OC(C)=O)c(I)c(C(=O)Cl)c1I,,CC(=O)N(C)C,,CCOC(C)=O,,test
US04110447,CC(O)(CCN1CCOCC1)c1ccccc1-c1ccccc1>>CC(CCN1CCOCC1)c1ccccc1-c1ccccc1,,CC(=O)O,,I,,test
US04444981,CCOC(=O)CC(C)=O.ClCc1cccc(Cl)c1>>CCOC(=O)CC(=O)CCc1cccc(Cl)c1,,C1CCOC1,,[Li]CCCC,[H-].[Na+],test
US20100311976A1,CN(C)CCN.NCC1CCC=CO1.O=C(n1ccnc1)n1ccnc1>>CN(C)CCNC(=O)NC[C@H]1CCC=CO1,,ClCCl,,,,test
US20140213571A1,COc1ccc2[nH]c(-c3nc(Cl)ccc3O)cc2n1.ClCI>>COc1ccc2c(cc3n2COc2ccc(Cl)nc2-3)n1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110190257A1,C=COCCONC(=O)c1ccc2sncc2c1Nc1ccc(I)cc1F>>O=C(NOCCO)c1ccc2sncc2c1Nc1ccc(I)cc1F,,CO,,Cl,,test
US20060063926A1,C#C[Si](C)(C)C.O=Cc1ccc(Br)cc1>>C[Si](C)(C)C#Cc1ccc(C=O)cc1,[Cu]I,C1CCOC1,,CCN(CC)CC,,test
US04242507,O=C(O)c1ccc([N+](=O)[O-])cc1.O=S(=O)(On1nnc2ccc(Cl)cc21)c1ccc(Cl)cc1>>O=C(On1nnc2ccc(Cl)cc21)c1ccc([N+](=O)[O-])cc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20140343070A1,CN(Cc1cc(-c2ccccc2)n(S(=O)(=O)c2cccc(Cl)c2)c1)C(=O)OC(C)(C)C.ClCCl>>CNCc1cc(-c2ccccc2)n(S(=O)(=O)c2cccc(Cl)c2)c1.Cl,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US03932496,C#CC(O)C(C)(C)CCCC.C1CCOCC1>>C#CC(OC1CCCCO1)C(C)(C)CCCC,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04870095,CCN(CC)CCN.CCOC(=O)Cn1cc(-c2ccccc2)c(-c2ccccc2)n1>>NC(=O)Cn1cc(-c2ccccc2)c(-c2ccccc2)n1,,CCOCC,,CCN(C(C)C)C(C)C,,test
US04500708,C=O.O=c1[nH]cc2c(c1-c1ccc(Cl)cc1)Nc1cc(Cl)ccc1S2>>O=c1c(-c2ccc(Cl)cc2)c2c(cn1CO)Sc1ccc(Cl)cc1N2,,CN(C)C=O,,[Na+].[OH-],,test
US20120046292A1,O=C(OCc1ccccc1)c1ccc(OC2CCC3(CC2)OCCO3)cc1>>O=C1CCC(Oc2ccc(C(=O)OCc3ccccc3)cc2)CC1,,CCO,,C1CCOC1,Cl,test
US04137320,CCCC(=O)Cl.Cc1csc2nc(CO)cn12>>CCCC(=O)OCc1cn2c(C)csc2n1.Cl,,ClC(Cl)Cl,,c1ccncc1,,test
US20060281789A1,O=C(CCl)N1CCOCC1.O=Cc1ccc(O)cc1>>O=Cc1ccc(OCC(=O)N2CCOCC2)cc1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20040106645A1,CC(Br)c1ccc2ncccc2c1.O=c1cc(NC2CCNCC2)c2cc(Cl)ccc2o1>>CC(c1ccc2ncccc2c1)N1CCC(Nc2cc(=O)oc3ccc(Cl)cc23)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120309739A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4ccncc4c3-c3ccccc3)cc2)CCC1>>NC1(c2ccc(-c3oc4ccncc4c3-c3ccccc3)cc2)CCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04851387,BrCCOC1CCCCO1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)C(CCOC1CCCCO1)P(=O)(OCC)OCC,,CN(C)C=O,,O,,test
US06162815,CCOC(=O)c1ccc(Sc2ccc3c(c2)C(C)(C)CCC3(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)c1ccc(S(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1,,O,,ClCCl,,test
US20070238726A1,COc1ccc(Cn2ncc3c(NCCN4CCOCC4)ccnc32)cc1.O=[N+]([O-])c1ccc(F)c(F)c1>>COc1ccc(Cn2ncc3c(N(CCN4CCOCC4)c4ccc([N+](=O)[O-])cc4F)ccnc32)cc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20140378686A1,CC(C)N1CCc2c(c(-c3ccc(F)cc3)nn2[C@@H]2c3cc(F)cc(F)c3C[C@H]2O)C1>>O[C@@H]1Cc2c(F)cc(F)cc2[C@H]1n1nc(-c2ccc(F)cc2)c2c1CCNC2,,CCO,,Cl,,test
US20030153610A1,C=CCNC(=O)c1ccc(Cl)s1.O=C(OO)c1cccc(Cl)c1>>O=C(NCC1CO1)c1ccc(Cl)s1,,ClCCl,,,,test
US20020120006A1,CO.Cc1ccc(CCCC(=O)O)cc1>>COC(=O)CCCc1ccc(C)cc1,,CO,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US20070185175A1,O=Cc1ccccc1F.SCCCS>>Fc1ccccc1C1SCCCS1,,ClCCl,,O=C1CCC(=O)N1Br,,test
US20070244159A1,CC(C)(C)C1Cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc2N1.O=CCCC(=O)O>>CC(C)(C)C1Cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc2N1CCCC(=O)O,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US20120059162A1,CC(C)(C)OC(=O)N(CC1CCOCC1)c1cc(Cl)nn2ccnc12.OC1CCCCC1>>CC(C)(C)OC(=O)N(CC1CCOCC1)c1cc(OC2CCCCC2)nn2ccnc12,,CCOC(C)=O,CN1CCCC1=O,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20130178459A1,COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc(CNC(=O)OC(C)(C)C)cc1.O=C1CCC(=O)N1Cl>>COc1cc(Cl)c2[nH]c(=O)c3sccc3c2c1-c1ccc(CNC(=O)OC(C)(C)C)cc1,,CN(C)C=O,,,,test
US20090137454A1,CC(C)(C)OC(=O)c1cc(OCCCCCCCCCC(=O)ON2C(=O)CCC2=O)cc(C(=O)OC(C)(C)C)c1.NCCCC(=O)O>>CC(C)(C)OC(=O)c1cc(OCCCCCCCCCC(=O)NCCCC(=O)O)cc(C(=O)OC(C)(C)C)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20160222021A1,C=C(C)C[C@@](C)(COc1ccc2c(c1)OCc1cnc(NC(C)=O)cc1-2)NC(=O)OCc1ccccc1>>CC(=O)Nc1cc2c(cn1)COc1cc(OC[C@@](C)(N)CC(C)C)ccc1-2,,CO,,C1CCOC1,,test
US06248739B1,CSCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCOCC3)ccc21.O=C(OO)c1cccc(Cl)c1>>CS(=O)Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCOCC3)ccc21,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05382585,CCn1c(=O)c([N+](=O)[O-])c2[nH]nnn2c1=O>>CCn1c(=O)[nH]c2no[n+]([O-])c2c1=O,,Cc1ccccc1C,,CC(=O)O,,test
US20150087646A1,CC(C)(C)C(=O)Cl.NCc1ccc(Cl)c(-c2nn(-c3ccc(F)c(Cl)c3)c(=O)[nH]2)c1>>CC(C)(C)C(=O)NCc1ccc(Cl)c(-c2nn(-c3ccc(F)c(Cl)c3)c(=O)[nH]2)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US05576340,CC(=O)CBr.COC(=O)Cc1ccc(O)c(Cl)c1>>COC(=O)Cc1ccc(OCC(C)=O)c(Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04690942,O=C(c1ccc(Oc2ccc(Cl)cc2Cl)cc1)C(F)n1cncn1>>OC(c1ccc(Oc2ccc(Cl)cc2Cl)cc1)C(F)n1cncn1,,CO,O,[BH4-].[Na+],,test
US20120171245A1,Cc1ccc(S(=O)(=O)n2cc(-c3ncc(F)c(N[C@H]4CCCN(C(=O)OC(C)(C)C)C4)n3)c3cc(Cl)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3ncc(F)c(N[C@H]4CCCNC4)n3)c3cc(Cl)cnc32)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080058335A1,COc1ccc(Cl)cc1C(=O)Nc1ncc(C(C)(C)C)s1.ICC1CCOCC1>>COc1ccc(Cl)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1CC1CCOCC1,,C1CCOC1,CN(C)C=O,CC(C)(C)[O-].[K+],,test
US20050267304A1,Cc1ccc(S(=O)(=O)n2c(-c3cccn3CC(=O)OC(C)(C)C)cc3cccnc32)cc1>>O=C(O)Cn1cccc1-c1cc2cccnc2[nH]1,,[K+],[OH-],Cl,ClCCl,test
US20110263598A1,COc1ccc2c(c1)C(=Cc1ccc3c(/C=C/c4ccc(N5CCN(C)CC5)nc4)n[nH]c3c1)C(=O)N2.ClCCl>>COc1ccc2c(c1)[C@]1(C[C@@H]1c1ccc3c(/C=C/c4ccc(N5CCN(C)CC5)nc4)n[nH]c3c1)C(=O)N2,,CO,ClC(Cl)Cl,CCN(CC)CC,CCOCC,test
US20110311458A1,COC(=O)C(Br)c1cccc(F)c1.Nc1cc(F)c(F)c(F)c1>>COC(=O)C(Nc1cc(F)c(F)c(F)c1)c1cccc(F)c1,,CC#N,,,,test
US05554613,Brc1cccnc1.OB(O)c1ccc(Br)cc1>>Brc1ccc(-c2cccnc2)cc1,,CCO,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],test
US05912247,CC(=O)O[C@H]1C=C[C@@H](Oc2nc(N3CCN(C(=O)OCc4ccccc4)CC3)nc3ccccc23)C1>>O=C(OCc1ccccc1)N1CCN(c2nc(O[C@@H]3C=C[C@H](O)C3)c3ccccc3n2)CC1,,CC(C)=O,,[Na+].[OH-],,test
US04675321,CCOC(=O)CC(C)=O.NC(N)=O.O=Cc1cccc([N+](=O)[O-])c1>>CCOC(=O)C1=CNC(=O)NC1c1cccc([N+](=O)[O-])c1,Cl,CCO,,,,test
US20080153836A1,COCCC(=O)c1cc(C(=O)OC)c(N)cc1C(F)(F)F.O=C(Cl)Cl>>COCCC(=O)c1cc(C(=O)OC)c(N=C=O)cc1C(F)(F)F,,Cc1ccccc1,,,,test
US20120070825A1,COC1(OC)C=CC(C(OC[C@H]2O[C@@H](n3cc([Se]C)c(N)nc3=O)C[C@@]2(O)[Si](C)(C)C(C)(C)C)(c2ccccc2)c2ccccc2)=CC1.O=C(Cl)c1ccccc1>>COC1(OC)C=CC(C(OC[C@H]2O[C@@H](n3cc([Se]C)c(NC(=O)c4ccccc4)nc3=O)C[C@@]2(O)[Si](C)(C)C(C)(C)C)(c2ccccc2)c2ccccc2)=CC1,,CCCCCC,,CCOC(C)=O,,test
US04331608,C=C(C(=O)OC)c1ccccc1.CCCCCCCC/C=C\CCCCCCCC(=O)O>>COC(=O)C(=O)c1ccccc1,,CC(=O)O,,,,test
US20130289033A1,Cc1ccccc1B(O)O.O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(I)cc1>>Cc1ccccc1-c1ccc(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US05236952,COc1cc(C(=O)CCCc2ccccc2)ccc1O.O=[N+]([O-])O>>COc1cc(C(=O)CCCc2ccccc2)cc([N+](=O)[O-])c1O,,CC(=O)O,CCOC(C)=O,,,test
US05849735,O=C(Cl)c1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1.c1ccc2c(c1)CNc1ccccc1O2>>O=C(Nc1ccc(C(=O)N2Cc3ccccc3Oc3ccccc32)cc1)c1ccccc1-c1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20120190124A1,C=CCCN.O=C1C=C(Br)C(=O)N1>>C=CCCNC1=CC(=O)NC1=O,,CO,,Cl,CC(=O)[O-].[Na+],test
US20130004420A1,CCCC[Sn](CCCC)(CCCC)c1ccc(CNC)cc1C(OCOC)(C(F)(F)F)C(F)(F)F.O=C1CCC(=O)O1>>CCCC[Sn](CCCC)(CCCC)c1ccc(CN(C)C(=O)CCC(=O)O)cc1C(OCOC)(C(F)(F)F)C(F)(F)F,,C1CCOC1,,,,test
US20110172230A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(F)c(O)c2)CC1.OCCC1CCCCC1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(F)c(OCCC3CCCCC3)c2)CC1,,C1CCOC1,CCOC(C)=O,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20110071126A1,COC(=O)C1(NS(=O)(=O)CC[Si](C)(C)C)c2cc(Br)ccc2CC12CNC2.Clc1ncccn1>>COC(=O)C1(NS(=O)(=O)CC[Si](C)(C)C)c2cc(Br)ccc2CC12CN(c1ncccn1)C2,,CO,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20130289016A1,C1CSCCN1.C=CS(=O)(=O)N1CCN(c2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4c(OC)cccc43)n2)CC1>>COc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCN(S(=O)(=O)CCN3CCSCC3)CC2)n1,,C1CCOC1,,,,test
US20150111866A1,COc1ncc(-c2ccc(C(=O)OC(C)(C)C)cc2C)cc1-c1cnc(N2CC(F)(F)C2)nc1CN1C(=O)O[C@H](c2cc(F)cc(C(F)(F)F)c2)[C@@H]1C>>COc1ncc(-c2ccc(C(=O)O)cc2C)cc1-c1cnc(N2CC(F)(F)C2)nc1CN1C(=O)O[C@H](c2cc(F)cc(C(F)(F)F)c2)[C@@H]1C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150299169A1,COc1ccc(CO[C@H]2CC(C)(C)Cc3nc(C4CCN(c5ncc(OCC6(C)COC(C)(C)OC6)cn5)CC4)c([C@@H](F)c4ccc(C(F)(F)F)cc4)c(C4CCC(F)(F)CC4)c32)cc1>>CC1(C)Cc2nc(C3CCN(c4ncc(OCC(C)(CO)CO)cn4)CC3)c([C@@H](F)c3ccc(C(F)(F)F)cc3)c(C3CCC(F)(F)CC3)c2[C@@H](O)C1,,C1COCCO1,,Cl,O=C([O-])O.[Na+],test
US05430171,CCCCOC(=O)CC(=O)CCl>>CCCCOC(=O)C[C@H](O)CCl,,ClCCl,,CCCCO,,test
US20050020645A1,CCOC(=O)CBr.Nc1ccc(Cl)cc1>>CCOC(=O)CNc1ccc(Cl)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140243322A1,CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OCCOCCOCCOCCOCCOCCOCCOCCN)ccc2-n2c(C)nnc21.COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)O)c1nnc(C)n1-2>>CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OCCOCCOCCOCCOCCOCCOCCOCCNC(=O)C[C@@H]3N=C(c4ccc(Cl)cc4)c4cc(OC)ccc4-n4c(C)nnc43)ccc2-n2c(C)nnc21,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20150094328A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Ic1c[nH]c2cccnc12>>CC(C)(C)OC(=O)n1cc(I)c2ncccc21,CN(C)c1ccncc1,ClCCl,,,,test
US20090286836A1,COC(=O)[C@@H](CC#Cc1cc(-c2ccc(F)cc2C)c(N(C)C(=O)C(C)(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cn1)NC(=O)OC(C)(C)C>>COC(=O)[C@H](N)CC#Cc1cc(-c2ccc(F)cc2C)c(N(C)C(=O)C(C)(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060030609A1,O=C(O)Cc1ccccc1F.O=[N+]([O-])O>>O=C(O)Cc1cc([N+](=O)[O-])ccc1F,,O=S(=O)(O)O,,,,test
US20070049610A1,CC(=O)c1nc2ccccc2cc1OS(=O)(=O)c1ccc(C)cc1.C[Mg]Cl>>Cc1ccc(S(=O)(=O)Oc2cc3ccccc3nc2C(C)(C)O)cc1,,C1CCOC1,,Cl,[Cl-].[NH4+],test
US04954518,CC(=O)O.Nc1cc(O)ccc1Oc1ccccc1>>CC(=O)Nc1cc(O)ccc1Oc1ccccc1,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20030078261A1,COC(=O)Cc1cccc(CN(CCOc2cccc(Cl)c2)S(=O)(=O)c2cccnc2)c1>>O=C(O)Cc1cccc(CN(CCOc2cccc(Cl)c2)S(=O)(=O)c2cccnc2)c1,,CO,,[Na+].[OH-],,test
US06498174B1,CCOC(=O)CC(=O)C(Br)CC.NC(=S)c1ccccc1>>CCc1sc(-c2ccccc2)nc1CC(=O)O,,Cc1ccccc1,,CO,O,test
US20100035883A1,Cn1ccnc1C=O.Nc1cc(F)cc2c1COC2=O>>Cn1ccnc1/C=N/c1cc(F)cc2c1COC2=O,,CC#N,,O=S(=O)([O-])[O-].[Mg+2],,test
US20140349972A1,Cl.Fc1cn[nH]c1.N#CN>>Cl.N=C(N)n1cc(F)cn1,,C1COCCO1,,,,test
US20110183954A1,C[C@H](N)c1ncc(F)cn1.Clc1nc(Cl)nc(Nc2cn(CCc3ccsc3)cn2)n1>>C[C@H](Nc1nc(Cl)nc(Nc2cn(CCc3ccsc3)cn2)n1)c1ncc(F)cn1,,CCOC(C)=O,,Cl,,test
US20020006932A1,O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCC2(CC1)C(=O)NCN2c1ccccc1.OB(O)c1ccncc1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCC2(CC1)C(=O)N(c1ccncc1)CN2c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20080009524A1,CC(=O)OC(C)=O.NS(=O)(=O)c1cccc(Br)c1>>CC(=O)NS(=O)(=O)c1cccc(Br)c1,CN(C)c1ccncc1,CCOC(C)=O,c1ccncc1,,,test
US20100210696A1,CCOC(C)=O.CCOC(C)=O.COc1cccc(Sc2sc(CN(C)C(=O)OC(C)(C)C)cc2-c2ccccc2F)c1>>CNCc1cc(-c2ccccc2F)c(Sc2cccc(OC)c2)s1.O=C(O)/C=C/C(=O)O,,CCO,,Cl,,test
US20130059834A1,CC(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(C)c4c3CC(C)(C)CC4)nc12>>CC(C)NC(=O)c1c[nH]c2ncc(-c3nn(C)c4c3CC(C)(C)CC4)nc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160222005A1,COc1ccnc(N)c1[N+](=O)[O-]>>COc1ccnc(N)c1N,[Fe],CC(C)O,,O,[Cl-].[NH4+],test
US20080153850A1,CC(C)(C)OC(=O)CNc1ncccc1-c1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1>>O=C(O)CNc1ncccc1-c1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20050256099A1,Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(C3CCN(Cc4ccccc4)CC3)CC2)cc2nc[nH]c12>>Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(C3CCNCC3)CC2)cc2nc[nH]c12,[Pd],CO,,[H][H],,test
US20130059850A1,Clc1ccc(SSc2ccc(Cl)cc2)cc1.Nc1ncccc1C#C[C@@H]1CC[C@@H](O)CC1>>O[C@@H]1CC[C@@H](c2[nH]c3ncccc3c2Sc2ccc(Cl)cc2)CC1,Cl[Pd]Cl,CS(C)=O,,CCOC(C)=O,,test
US20130252953A1,Cc1cc(C)c2c(=O)[nH]sc2n1.O=C(CCl)N1CCOCC1>>Cc1cc(C)c2c(OCC(=O)N3CCOCC3)nsc2n1,,ClCCl,,CCN(CC)CC,,test
US20100305145A1,BrCc1ccccc1.C[C@H](C[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)OC(C)(C)C)C(=O)O>>C[C@H](C[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150329506A1,O=C(Nc1ccc(F)c(CO)c1)c1ccc(Cl)cn1>>O=Cc1cc(NC(=O)c2ccc(Cl)cn2)ccc1F,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US04548932,CCOC(=O)[C@H](CCC1CCOCC1)N[C@H]1COc2ccccc2N(CC(=O)O)C1=O>>O=C(O)CN1C(=O)[C@@H](N[C@@H](CCC2CCOCC2)C(=O)O)COc2ccccc21,,[Na+],[OH-],CC(=O)O,Cl,test
US04432984,O=[N+]([O-])c1ccc2c(c1)OC(CCl)CO2>>Nc1ccc2c(c1)OC(CCl)CO2,[Pd],CCO,,,,test
US20050014787A1,CC(=O)c1ccc(CCNC(=O)C(F)(F)F)cc1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)C=C(C)c1ccc(CCNC(=O)C(F)(F)F)cc1,,C1CCOC1,,O,[H-].[Na+],test
US20060100230A1,CCOC(=O)COc1ccc(S(=O)(=O)Cl)cc1C.Cc1cc(Br)cc2c1NC(C)C2C>>CCOC(=O)COc1ccc(S(=O)(=O)N2c3c(C)cc(Br)cc3C(C)C2C)cc1C,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US04927838,CCCCc1c(/C=C/C(=O)OC)ccc2cc(OC)ccc12>>CCCCc1c(/C=C/C(=O)O)ccc2cc(OC)ccc12,,CO,,Cl,[Na+].[OH-],test
US20070179165A1,CCI.Cc1ccc(-n2ccc3c(Cl)n[nH]c(=O)c32)c(C)c1>>CCn1nc(Cl)c2ccn(-c3ccc(C)cc3C)c2c1=O,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20040132745A1,CO.O=C(O)COc1ccc([N+](=O)[O-])cc1>>COC(=O)COc1ccc([N+](=O)[O-])cc1,,Cl,,,,test
US20150018363A1,Cn1c(CC(C)(C)C)nc2ccc(Br)cc21.O=c1cc(OCc2ccc(F)cc2)cc[nH]1>>Cn1c(CC(C)(C)C)nc2ccc(-n3ccc(OCc4ccc(F)cc4)cc3=O)cc21,I[Cu]I,CS(C)=O,,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US20020022612A1,CCOC(=O)CCOc1ccc(Cl)cc1C>>Cc1cc(Cl)ccc1OCCC(=O)O,,C1CCOC1,O,[Li]O,,test
US05112988,O=C(NCC1C2(CCCC1(c1ccccc1)c1ccccc1)OCCO2)c1ccccc1>>c1ccc(CNCC2C3(CCCC2(c2ccccc2)c2ccccc2)OCCO3)cc1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050085465A1,C#CCN(C)CCO.COc1cc2c(Cl)ncnc2cc1O>>C#CCN(C)CCOc1cc2ncnc(Cl)c2cc1OC,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090170907A1,C[Si](C)(C)C=[N+]=[N-].N#Cc1ccc(N(Cc2nnn[nH]2)CC(F)(F)F)cc1C(F)(F)F>>Cn1nnc(CN(CC(F)(F)F)c2ccc(C#N)c(C(F)(F)F)c2)n1,,CO,,,,test
US20070082912A1,CCOC(=O)c1cccc(-n2c(C)ccc2-c2ccccc2OCc2ccc(OC)cc2)c1>>COc1ccc(COc2ccccc2-c2cccn2-c2cccc(C(=O)O)c2)cc1,,CCO,,[Na+].[OH-],,test
US05580866,CS(=O)(=O)N1CCSc2cccc(Cl)c2C1.O=C(OO)c1cccc(Cl)c1>>CS(=O)(=O)N1CCS(=O)c2cccc(Cl)c2C1,,ClCCl,,,,test
US05883093,CC(C)(C)[Si](C)(C)OC1CN(c2ccc(NC(=O)OCc3ccccc3)cc2F)C1.CCCC(=O)OC[C@H]1CO1>>CC(C)(C)[Si](C)(C)OC1CN(c2ccc(N3C[C@H](CO)OC3=O)cc2F)C1,,C1CCOC1,,,,test
US20130059832A1,Cc1ccc(C(=O)O)cc1NC(=O)c1cnc2ccccn12.NC(=NO)N1CCOCC1>>Cc1ccc(-c2nc(N3CCOCC3)no2)cc1NC(=O)c1cnc2ccccn12,,CN1CCCC1=O,,O=C(n1ccnc1)n1ccnc1,,test
US20130137865A1,Cn1ncc(I)c1CCc1ccc(C(F)(F)F)cc1.c1cn[nH]c1>>Cn1ncc(-n2cccn2)c1CCc1ccc(C(F)(F)F)cc1,[Cu]I,CN(C)C=O,O,CN[C@@H]1CCCC[C@H]1NC,O=C([O-])[O-].[K+].[K+],test
US20120129884A1,O=c1[nH]c2c(cc1S(=O)(=O)c1ccccc1)CCc1ccn(S(=O)(=O)c3ccccc3)c1-2>>O=c1[nH]c2c(cc1S(=O)(=O)c1ccccc1)CCc1cc[nH]c1-2,,CCO,,Cl,[K+].[OH-],test
US20050070561A1,COc1cc2c(c(OC)c1)C(=O)C(=O)N2.Cl>>COc1cc(N)c(C(=O)O)c(OC)c1.Cl,,[Na+],[OH-],OO,,test
US06150373,O=C1c2ccccc2C(=O)N1CCc1cccc(N2C(=O)N(c3cc(Cl)ccc3Cl)Cc3cnc(Nc4ccccc4)nc32)c1>>NCCc1cccc(N2C(=O)N(c3cc(Cl)ccc3Cl)Cc3cnc(Nc4ccccc4)nc32)c1,,CO,,NN,O,test
US20030078282A1,CCCCC([Sn])=C(CCCC)CCCC.CCc1cccc(Br)c1.CN(C)C=O>>C=Cc1cccc(CC)c1,,CN(C)C=O,,,,test
US20110237573A1,CCOC(=O)C(F)(F)Br.CCOC(=O)Cc1ccc(-c2ccnc(Br)c2)cc1>>CCOC(=O)Cc1ccc(-c2ccnc(C(F)(F)C(=O)OCC)c2)cc1,,CN(C)C=O,,,,test
US20060205969A1,CC(C)c1cccc(C(C)C)c1OC(=O)OC[C@H](N)C(=O)O.CS(=O)(=O)O>>CC(C)c1cccc(C(C)C)c1OC(=O)OC[C@H](N)C(=O)O.CS(=O)(=O)O,,O,,,,test
US20040053908A1,Nc1cc(Oc2ccc(N)c(Cl)c2)ccn1.O=C1CCC(=O)N1Br>>Nc1ccc(Oc2ccnc(N)c2Br)cc1Cl,,O,,CC(C)O,,test
US20090062259A1,O=C(O)Cc1ccc(-c2cccc(CN3Cc4ccccc4C3)c2)cc1>>OCCc1ccc(-c2cccc(CN3Cc4ccccc4C3)c2)cc1,,C1CCOC1,,B,,test
US20070259851A1,O=C(O)C[C@@H]1Cc2cc(Cl)c3[nH]ncc3c2CN(CC(F)(F)F)C1=O.O=C1NC(=O)C(C2CCNCC2)N1>>O=C1NC(=O)C(C2CCN(C(=O)C[C@@H]3Cc4cc(Cl)c5[nH]ncc5c4CN(CC(F)(F)F)C3=O)CC2)N1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20140243283A1,CC(C)[Si](O[C@@H]1[C@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H](C#Cc2ccc([C@H]3O[C@H](COC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@H](OC(=O)C(C)(C)C)[C@@H]3OC(=O)C(C)(C)C)cc2)O[C@H](CO)[C@H]1O[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C>>CC(C)(C)C(=O)OC[C@H]1O[C@H](c2ccc(C#C[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)cc2)[C@@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20040209948A1,CC1CN(Cc2ccccc2)CCC1=NO>>CC1CN(Cc2ccccc2)CCC1N,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110065702A1,Nc1ccc2c(c1)CC(=O)N2.O=Cc1ccc2[nH]nnc2c1>>Nc1ccc2c(c1)/C(=C\c1ccc3[nH]nnc3c1)C(=O)N2,,CCO,,C1CCNCC1,,test
US20060257987A1,COC(=O)CCc1ccc(OCCC(C)OS(C)(=O)=O)cc1C.O=C(c1ccccc1)c1cc(Br)ccc1O>>COC(=O)CCc1ccc(OCCC(C)Oc2ccc(Br)cc2C(=O)c2ccccc2)cc1C,,CN(C)C=O,O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20150210690A1,CCOC(=O)[C@H](CO)C[C@@H](Cc1ccc(-c2cc(Cl)ccc2F)cc1)NC(=O)OC(C)(C)C.O=S(=O)(Cl)c1ccc(Br)cc1>>CCOC(=O)[C@H](COS(=O)(=O)c1ccc(Br)cc1)C[C@@H](Cc1ccc(-c2cc(Cl)ccc2F)cc1)NC(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20150166558A1,CC(=O)Nc1cccc(C(Cn2c(=O)c3c(n(Cc4c(F)cccc4C(F)(F)F)c2=O)COC32CCN(Cc3ccc(C(F)(F)F)o3)CC2)NC(=O)OC(C)(C)C)c1>>CC(=O)Nc1cccc(C(N)Cn2c(=O)c3c(n(Cc4c(F)cccc4C(F)(F)F)c2=O)COC32CCN(Cc3ccc(C(F)(F)F)o3)CC2)c1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20130274253A1,CC(C)C1Cc2ccccc2N1.CCOC(C)=O.CN(C)C=O.O.c1ccncc1>>CC(C)C1Cc2ccccc2N1C(=O)[C@@H](C)OCc1ccccc1,,CN(C)C=O,,CCN=C=NCCCN(C)C,Cl,test
US20150297586A1,ClCCCCn1cnc2ccccc21.c1coc(N2CCNCC2)c1>>c1coc(N2CCN(CCCCn3cnc4ccccc43)CC2)c1,,CC#N,,CCN(C(C)C)C(C)C,[I-].[K+],test
US04898862,CCOC(=O)NC(C)C(=O)c1ccc(OCC(=O)NCCc2ccc(OC)c(OC)c2)c(Cl)c1.NN>>COc1ccc(CCNC(=O)COc2ccc(C3=NNC(=O)NC3C)cc2Cl)cc1OC,,CCCCO,,O,,test
US20040082780A1,CC(=O)OC(C)=O.Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)cccc2o1>>CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)cccc2o1,,c1ccncc1,,,,test
US04760142,Cn1c(=O)c2[nH]c(CCCC(=O)O)nc2n(C)c1=O>>Cn1c(=O)c2c(nc3n2C(=O)CCC3)n(C)c1=O,,CC(=O)OC(C)=O,,,,test
US20070213336A1,CCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2O)c1.CCOCCBr>>CCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2OCCOCC)c1,,CCC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20060281772A1,COc1cc2ncnc(C3CCNCC3)c2cc1OC.O=C=Nc1ccc(OC(F)(F)F)cc1>>COc1cc2ncnc(C3CCN(C(=O)Nc4ccc(OC(F)(F)F)cc4)CC3)c2cc1OC,,CN(C)C=O,,,,test
US20100197683A1,CC1(C)CO1.CC1(O)CCC2(CC1)OCCO2>>CC(C)(O)COC1(C)CCC2(CC1)OCCO2,,CN(C)C=O,O,[H-].[Na+],,test
US20020013466A1,COC(=O)C(C)Br.Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3cccc(O)c3)c(C#N)cc2F)c1=O>>COC(=O)C(C)Oc1cccc(Oc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2C#N)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060257987A1,COC(=O)CCc1ccc(OCC[C@H](C)Oc2ccc(Cl)cc2-c2ccccc2F)cc1C>>Cc1cc(OCC[C@H](C)Oc2ccc(Cl)cc2-c2ccccc2F)ccc1CCC(=O)O,,CO,,Cl,[Na+].[OH-],test
US20110003787A1,COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)nc2)cc(-c2ccc(C3=N[C@H]([C@@H](C)O)CO3)[nH]2)c1>>C[C@@H](CO)Oc1cc(Oc2ccc(S(C)(=O)=O)nc2)cc(-c2ccc(C3=N[C@H]([C@@H](C)O)CO3)[nH]2)c1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20120040991A1,CC(C)(C)OC(=O)N1C[C@H]2C[C@H]2C[C@H]1CO>>CC(C)(C)OC(=O)N1C[C@H]2C[C@H]2C[C@H]1C=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20030017948A1,CCOC(=O)Cl.CCS(=O)(=O)Nc1cc(N)c(F)cc1Br>>CCOC(=O)Nc1cc(NS(=O)(=O)CC)c(Br)cc1F,,ClCCl,,O,c1ccncc1,test
US04183741,CC(=O)CCl.Cc1ccn2nc(-c3ccccn3)nc2c1>>CC(=O)C[n+]1ccccc1-c1nc2cc(C)ccn2n1.[Cl-],,CCOCC,,,,test
US20020169200A1,COC(=O)CCc1cc2cc(OCCCNC(=O)OCc3ccccc3)ccc2[nH]1>>COC(=O)CCc1cc2cc(OCCCN)ccc2[nH]1,[Pd],CCO,,,,test
US20090186898A1,Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1B1OC(C)(C)C(C)(C)O1.O=C(c1ccc(Nc2cc(Cl)nn3ccnc23)nc1)N1CCOCC1>>Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1-c1cc(Nc2ccc(C(=O)N3CCOCC3)cn2)c2nccn2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,O,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20120010208A1,Cc1cn2nc(Cl)ccc2n1.ClI>>Cc1nc2ccc(Cl)nn2c1I,,CO,ClC(Cl)Cl,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20050261276A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.O=S(=O)(c1ccc(Cl)cc1)C(c1cc(F)ccc1F)C1CCNCC1>>O=S(=O)(c1ccc(Cl)cc1)C(c1cc(F)ccc1F)C1CCN(S(=O)(=O)C(F)(F)F)CC1,,ClCCl,,CCN(CC)CC,,test
US20160068559A1,CC(C)N(CCCN)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>CC(C)N(CCCNC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21,,ClCCl,,,,test
US20020077318A1,CC(C)(C)OC(=O)N1CCc2c(n(CCN)c3ccccc23)CC1.O=C(Cl)c1ccccc1>>CC(C)(C)OC(=O)N1CCc2c(n(CCNC(=O)c3ccccc3)c3ccccc23)CC1,,C1CCOC1,,O=C(O)CC(O)(CC(=O)O)C(=O)O,,test
US20070299120A1,COc1ccc(CCN2C(=O)N(N)C[C@H]2c2ccc(OC)cc2)cc1.CS(=O)(=O)Cl>>COc1ccc(CCN2C(=O)N(NS(C)(=O)=O)C[C@H]2c2ccc(OC)cc2)cc1,,ClCCl,,c1ccncc1,,test
US20100298290A1,Cc1ncnc(N2CCOc3ccc(-c4ccc5nc(NC(=O)c6ccccc6)sc5n4)cc3C2)c1Cc1ccc(F)cc1>>Cc1ncnc(N2CCOc3ccc(-c4ccc5nc(N)sc5n4)cc3C2)c1Cc1ccc(F)cc1,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20150322056A1,Ic1cc[nH]n1.OB(O)c1ccc(F)cc1>>Fc1ccc(-n2ccc(I)n2)cc1,,ClCCl,,,,test
US20140051672A1,C(=NC1CCCCC1)=NC1CCCCC1.CCOCC.CN1CCOCC1.O=CNCC(=O)O.On1nnc2ccccc21>>COc1cc(CCNC(=O)CNC=O)ccc1OC(C)C,,CCOCC,,C1CCOC1,,test
US20070129393A1,CNC(=O)Cc1ccc(OC)cc1O.O=[N+]([O-])c1cccc(S(=O)(=O)OC[C@@H]2CO2)c1>>CNC(=O)Cc1ccc(OC)cc1OC[C@@H]1CO1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070072865A1,O=C1OC(c2ccccc2)(c2ccccc2)C2CNCCCN12.O=C=NCc1ccc(F)cc1>>O=C(NCc1ccc(F)cc1)N1CCCN2C(=O)OC(c3ccccc3)(c3ccccc3)C2C1,,C1CCOC1,,,,test
US20160137637A1,N#Cc1ccc2[nH]c(N)nc2c1.O=C(O)c1csc(-c2ccc3c(c2)CCO3)n1>>N#Cc1ccc2[nH]c(NC(=O)c3csc(-c4ccc5c(c4)CCO5)n3)nc2c1,CN(C)c1ccncc1,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040010141A1,CCOC(=O)C1(C(=O)OCC)CCCN1c1ccc(Oc2ccc3c(cnn3-c3ccc(C#N)cc3)c2)nc1.NC(N)=O>>N#Cc1ccc(-n2ncc3cc(Oc4ccc(N5CCCC56C(=O)NC(=O)NC6=O)cn4)ccc32)cc1,,CCO,,[Na],,test
US04205072,CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](N)[C@H]2SC1.O=C(O)Cc1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)Cc3csc(NC(c4ccccc4)(c4ccccc4)c4ccccc4)n3)[C@H]2SC1,,C1CCOC1,O,CC(C)COC(=O)Cl,CN1CCOCC1,test
US03969354,CN1CCNC1=C[N+](=O)[O-].ClSc1ccccc1>>CN1CCNC1=C(Sc1ccccc1)[N+](=O)[O-],,c1ccncc1,,,,test
US20050049262A1,CS(=O)(=O)Cl.C[C@H](O)CCCCn1c(=O)c2c(ncn2C)n(C)c1=O>>C[C@@H](CCCCn1c(=O)c2c(ncn2C)n(C)c1=O)OS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US05250735,CCCCC=O.O=C1CCCC1>>CCCC/C=C1\CCCC1=O,,CC(=O)O,,[Na+].[OH-],,test
US20160039838A1,Nc1cc2c(Nc3ccc(OCc4ccccn4)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1.O=C(Cl)/C=C/CBr>>O=C(/C=C/CBr)Nc1cc2c(Nc3ccc(OCc4ccccn4)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1,,C1CCOC1,,O,,test
US20040043993A1,O=Cc1cc(Br)c(O)c(Br)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=Cc1cc(Br)c(OS(=O)(=O)C(F)(F)F)c(Br)c1,,c1ccncc1,,O,,test
US06046213,O=C(OCC(Cl)(Cl)Cl)N1C2CCC1CC(Sc1ccc(F)cc1)C2>>Fc1ccc(SC2CC3CCC(C2)N3)cc1,,CC(=O)O,,Br,[Na+].[OH-],test
US20100022527A1,CC(=O)O.Cc1cc(-c2ccc(C)c([N+](=O)[O-])c2)c(Cl)cc1C1=C(O)C2(CCCCC2)OC1=O>>CC(=O)Nc1cc(-c2cc(C)c(C3=C(O)C4(CCCCC4)OC3=O)cc2Cl)ccc1C,[Fe],,,CS(=O)(=O)Cl,,test
US05001157,Cc1ccc(C(=O)N=C=S)cc1.NC(=O)c1ccccc1N>>Cc1ccc(C(=O)NC(=S)Nc2ccccc2C(N)=O)cc1,,CCOCC,,,,test
US20100261723A1,CNc1ccc(-c2nc(CS(C)(=O)=O)cc(N3CCOC[C@@H]3C)n2)cc1.O=C(O)c1ccno1>>C[C@H]1COCCN1c1cc(CS(C)(=O)=O)nc(-c2ccc(N(C)C(=O)c3ccno3)cc2)n1,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160176826A1,CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3ncc(Br)c(NCC4CCCO4)n3)cc2)CC1.O=C(O)C(F)(F)F>>Brc1cnc(Nc2ccc(N3CCNCC3)cc2)nc1NCC1CCCO1.O=C(O)C(F)(F)F,,ClCCl,,Cl,,test
US07015218B1,CC(C)(C)COc1ccc(N)cc1C#N.Cc1cc(C(=O)O)nn1-c1ccc(F)cc1>>Cc1cc(C(=O)Nc2ccc(OCC(C)(C)C)c(C#N)c2)nn1-c1ccc(F)cc1,,CN(C)C=O,O,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20150252022A1,Cc1cc2cc(-c3cnn(C4CCCCO4)c3)ccc2[nH]1.Cc1ccc(S(=O)(=O)OCC2CC(C)N(Cc3ccccc3)C2)cc1>>Cc1cc2cc(-c3cnn(C4CCCCO4)c3)ccc2n1CC1CC(C)N(Cc2ccccc2)C1,,O,,CN(C)C=O,[H-].[Na+],test
US20030149034A1,CC(C)(C)OC(=O)Nc1nc(CC(=O)Nc2n[nH]c3ccc(N4CCCS4(=O)=O)cc23)cs1>>Nc1nc(CC(=O)Nc2n[nH]c3ccc(N4CCCS4(=O)=O)cc23)cs1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160263087A1,C[Si](C)(C)N=C=O.O=S(=O)(c1ccccc1)n1cc(-c2cnn(C3CCNCC3)c2)c2ccc(F)cc21>>NC(=O)N1CCC(n2cc(-c3cn(S(=O)(=O)c4ccccc4)c4cc(F)ccc34)cn2)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20090270355A1,CCCCc1cc(OC2CCN(C(=O)OC(C)(C)C)CC2)c2ncccc2c1>>CCCCc1cc(OC2CCNCC2)c2ncccc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4c(Br)c(F)ccc4nn23)CC1.Cl>>Cl.O=c1cc(C2CCNCC2)n2nc3ccc(F)c(Br)c3c2[nH]1,,C1COCCO1,,,,test
US05202351,CC(C)c1cccc(C(C)C)c1N.CCCCCC(C(=O)O)c1cccc2c1OCO2.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CCCCCC(NC(=O)Nc1c(C(C)C)cccc1C(C)C)c1cccc2c1OCO2,,Cc1ccccc1,,CCN(CC)CC,,test
US20060258725A1,Cc1cc(OCc2c(-c3c(Cl)cccc3Cl)noc2C(C)C)ccc1[N+](=O)[O-]>>Cc1cc(OCc2c(-c3c(Cl)cccc3Cl)noc2C(C)C)ccc1N,,CCO,,O,O=C([O-])[O-].[Na+].[Na+],test
US04975462,COC(=O)CC#N.O=C=Nc1ccc(C(F)(F)F)cc1>>COC(=O)C(C#N)C(=O)Nc1ccc(C(F)(F)F)cc1,,C1CCOC1,,[H-].[Na+],,test
US05693651,C=CC(=O)OC.Cl.Nc1cnc2cc(OCc3ccccc3)ccc2c1>>COC(=O)C(Cl)Cc1cnc2cc(OCc3ccccc3)ccc2c1,,CC(C)=O,O,O=N[O-].[Na+],,test
US20080188528A1,COC(=O)[C@H](CCCCNC(=N)NS(=O)(=O)c1c(C)c(C)c2c(c1C)CCC(C)(C)O2)NC(=O)c1cccn(Cc2ccccc2)c1=O>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCCC[C@H](NC(=O)c2cccn(Cc3ccccc3)c2=O)C(=O)O)c(C)c2c1OC(C)(C)CC2,,CO,O,[Na+].[OH-],,test
US04014677,CCC(C)Nc1nc(Cl)nc(C)c1[N+](=O)[O-].CO>>CCC(C)Nc1nc(OC)nc(C)c1[N+](=O)[O-],,CO,,C[O-].[Na+],,test
US04695566,N#CCCl.O=C1CC(c2ccccc2)NN1>>N#CCOc1cc(-c2ccccc2)[nH]n1,,CN(C)C=O,,[H-].[Na+],,test
US20070281933A1,CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1.NC(=O)c1cc(-c2ccccc2)cc2c(C3CCNCC3)n[nH]c12>>CC(=O)Nc1ccc(S(=O)(=O)N2CCC(c3n[nH]c4c(C(N)=O)cc(-c5ccccc5)cc34)CC2)cc1,CN(C)c1ccncc1,,,CCN(C(C)C)C(C)C,Cl,test
US20150329548A1,C[C@@H](N)C1CCC1.Cc1cccc(-c2cc3nc(Cl)nc(Cl)c3n2Cc2ccc(C(F)(F)F)cc2[N+](=O)[O-])c1>>Cc1cccc(-c2cc3nc(Cl)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2[N+](=O)[O-])c1,,CCO,CCOC(C)=O,CCN(CC)CC,Cl,test
US09227995B2,CC#COC[C@H](NC(=O)OC(C)(C)C)C(=O)NC(C)(C)C(=O)OC.O=C(O)C(F)(F)F>>CC#COC[C@H](N)C(=O)NC(C)(C)C(=O)OC.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20050009831A1,NC(=O)c1c(Cl)c(-c2ccccc2)n2c1CNCC2.O=C(Cl)Oc1ccccc1>>NC(=O)c1c(Cl)c(-c2ccccc2)n2c1CN(C(=O)Oc1ccccc1)CC2,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20090270405A1,COc1ncccc1B(O)O.Nc1cc(Br)ccn1>>COc1ncccc1-c1ccnc(N)c1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US06156907,C=C(Cl)C#N.N#Cc1ccc(CN=[N+]=[N-])cc1>>N#Cc1ccc(Cn2cc(C#N)nn2)cc1,,O,,,,test
US20040204454A1,CC(=O)OC(C)=O.O=C(N[C@H]1CNC[C@H]1NC(=O)c1ccc(Cl)s1)c1ccc(-n2ccccc2=O)cc1>>CC(=O)N1C[C@H](NC(=O)c2ccc(-n3ccccc3=O)cc2)[C@H](NC(=O)c2ccc(Cl)s2)C1,,C1CCOC1,,CCN(CC)CC,,test
US06294566B1,CC(=O)c1cc(-c2ccccc2)nc2ccccc12>>CC(O)c1cc(-c2ccccc2)nc2ccccc12,,CO,,[BH4-].[Na+],,test
US20050107347A1,COC(=O)C(O)Cc1cc(Br)c(Oc2cc(/C=C/c3ccncc3)c(O)c(C(C)C)c2)c(Br)c1>>CC(C)c1cc(Oc2c(Br)cc(CC(O)C(=O)O)cc2Br)cc(/C=C/c2ccncc2)c1O,,C1CCOC1,,[Li+].[OH-],,test
US20060111357A1,Cc1cc(O)nc2ccc([N+](=O)[O-])cc12.O=P(Cl)(Cl)Cl>>Cc1cc(Cl)nc2ccc([N+](=O)[O-])cc12,,O,,,,test
US20080058293A1,C[C@H](CC(=O)Nc1c(Cl)ccc2nc(N3CC[C@@H](OS(C)(=O)=O)C3)ccc12)c1ccccc1.NCCCO>>C[C@H](CC(=O)Nc1c(Cl)ccc2nc(N3CC[C@H](NCCCO)C3)ccc12)c1ccccc1,,CC#N,,,,test
US20110098324A1,CC(N)c1ccccc1.CCOC(=O)CNC(=O)c1c(O)c(C(=O)OC)c(O)n(Cc2ccccc2Cl)c1=O>>CC(NC(=O)c1c(O)c(C(=O)NCC(=O)O)c(=O)n(Cc2ccccc2Cl)c1O)c1ccccc1,,ClC(Cl)Cl,,,,test
US20040037022A1,Nc1ccc(C[C@@H](CO)N(Cc2ccccc2)C[C@H](O)COc2ccccc2)cc1.O=C(Cl)c1ccccc1>>O=C(Nc1ccc(C[C@@H](CO)N(Cc2ccccc2)C[C@H](O)COc2ccccc2)cc1)c1ccccc1,,ClCCl,,c1ccncc1,,test
US20040077640A1,CC(C)(C)OC(=O)N1CCC(c2nc(-c3ccc(-c4ccccc4)cc3)c[nH]2)CC1.Cl>>Cl.c1ccc(-c2ccc(-c3c[nH]c(C4CCNCC4)n3)cc2)cc1,,CCOC(C)=O,,,,test
US20110212946A1,Cn1c(=O)c(CN(C(=O)C2CCCCC2)C2(C)CCN(Cc3ccccc3)C2)cc2ccccc21>>Cn1c(=O)c(CN(C(=O)C2CCCCC2)C2(C)CCNC2)cc2ccccc21,[Pd],CO,,O=C[O-].[NH4+],,test
US06124323,Cc1ccc(S(=O)(=O)OCCOc2ccccc2)cc1.Cl.Fc1cccc(CC2CCNCC2)c1>>Cl.Fc1cccc(CC2CCN(CCOc3ccccc3)CC2)c1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20070232591A1,Clc1ccc(-n2ncc3c2CCNC3)nn1.O=C(CCl)N1CCN(C2CCC2)CC1>>O=C(CN1CCc2c(cnn2-c2ccc(Cl)nn2)C1)N1CCN(C2CCC2)CC1,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US04331666,CON=C(C(=O)O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1.ClP(Cl)(Cl)(Cl)Cl>>CON=C(C(=O)Cl)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,ClCCl,,CCN(CC)CC,,test
US04889855,CCOC(=O)C(=O)Nc1ccc2ccccc2c1[N+](=O)[O-].O=[N+]([O-])O>>CCOC(=O)C(=O)Nc1ccc2cccc([N+](=O)[O-])c2c1[N+](=O)[O-],,O=S(=O)(O)O,,,,test
US06071932,OC(CCl)Cn1c2ccccc2c2ccccc21.OC1(c2ccccc2)CCNCC1>>Cl.OC(CN1CCC(O)(c2ccccc2)CC1)Cn1c2ccccc2c2ccccc21,,CC(=O)CC(C)C,,O=C([O-])[O-].[K+].[K+],,test
US04587236,CCC(=O)OC(=O)CC.CCC(=O)O[C@]1(C(=O)CO)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C>>CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C,,c1ccncc1,,,,test
US20130303500A1,CC(=O)O[C@H]1CC[C@@]2(CO[Si](C)(C)C(C)(C)C)C(=CCC3C2CC[C@]2(C)C(=O)CCC32)C1.O>>CC(C)(C)[Si](C)(C)OC[C@]12CC[C@H](O)C[C@@H]1[C@@H](O)CC1C2CC[C@@]2(C)C1CC[C@@H]2O,,C1CCOC1,,,,test
US20160095844A1,CC1(C)C(=O)Nc2cc(Br)ccc21.COc1ccc(CBr)cc1>>COc1ccc(CN2C(=O)C(C)(C)c3ccc(Br)cc32)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06251911B1,C[C@H](NC(=O)OC(C)(C)C)C(=O)NCc1ccc(Nc2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)cc1>>C[C@H](N)C(=O)NCc1ccc(Nc2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)cc1,,CCOCC,,Cl,,test
US20050209260A1,COc1ccc(O)c(C(C)=O)c1.C[Mg]Br>>COc1ccc(O)c(C(C)(C)O)c1,,C1CCOC1,,,,test
US20160046618A1,CC(O)c1ncco1.Cc1nc(Cl)cnc1C(=O)OC(C)(C)C>>Cc1nc(OC(C)c2ncco2)cnc1C(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160137647A1,CCO[C@H]1CNC(CO)C1.COc1cc(C(=O)O)cc2nc(NC(CF)c3cccc(Cl)c3)oc12>>CCO[C@@H]1CC(CO)N(C(=O)c2cc(OC)c3oc(NC(CF)c4cccc(Cl)c4)nc3c2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080275027A1,C1CCNC1.COC(=O)c1ccc(C(=O)Cl)cc1>>O=C(O)c1ccc(C(=O)N2CCCC2)cc1,,ClCCl,,CCN(CC)CC,,test
US20050026935A1,BrBr.Cc1cc2c(=O)[nH]c(=O)[nH]c2s1>>Cc1sc2[nH]c(=O)[nH]c(=O)c2c1Br,,O,,CC(=O)O,,test
US20080306102A1,Cc1ccccc1O.O=C(CBr)N1CCC2(CC1)C(=O)Nc1ccccc12>>Cc1ccccc1OCC(=O)N1CCC2(CC1)C(=O)Nc1ccccc12,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20090023763A1,Nc1cc(-c2ccncc2)c(-c2cccs2)nc1N.O=C(c1ncc[nH]1)c1ncc[nH]1>>O=c1[nH]c2cc(-c3ccncc3)c(-c3cccs3)nc2[nH]1,,C1COCCO1,,,,test
US03948987,O=[N+]([O-])c1ccc(Cl)cc1C(F)(F)F.Sc1ccccc1>>O=[N+]([O-])c1ccc(Sc2ccccc2)cc1C(F)(F)F,,O,,CCO,[Na+].[OH-],test
US20120053174A1,Cc1cc(N)n[nH]1.O=C(c1ccc(F)cn1)c1nc(Cl)c2ccccc2n1>>Cc1cc(Nc2nc(C(=O)c3ccc(F)cn3)nc3ccccc23)n[nH]1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,[I-].[K+],test
US20020193447A1,CC(C)(C)[Si](C)(C)Oc1ccc([C@@H](O)C[N+](=O)[O-])cc1O[Si](C)(C)C(C)(C)C>>CC(C)(C)[Si](C)(C)Oc1ccc([C@@H](O)CN)cc1O[Si](C)(C)C(C)(C)C,[Pd],CO,,[H][H],,test
US20090215758A1,Clc1cccnc1N1CCNCC1.N.S=C(n1ccnc1)n1ccnc1>>NC(=S)N1CCN(c2ncccc2Cl)CC1,,C1CCOC1,CO,,,test
US04309354,NS(=O)(=O)O.O=Cc1coc2cc(OC(=O)OCC(Cl)(Cl)Cl)c(OC(=O)OCC(Cl)(Cl)Cl)cc2c1=O>>O=C(OCC(Cl)(Cl)Cl)Oc1cc2occ(C(=O)O)c(=O)c2cc1OC(=O)OCC(Cl)(Cl)Cl,,ClCCl,O,[Na+].[O-]Cl,,test
US20130261133A1,C=C[C@@H](C#CC#C[C@H](N)CCCC1CCCCC1)OC(C)=O.O=C(OC(=O)c1ccccc1)c1ccccc1>>C=C[C@@H](C#CC#C[C@@H](CCCC1CCCCC1)NC(=O)c1ccccc1)OC(C)=O,,ClCCl,,CCN(CC)CC,,test
US20070244159A1,CCCC(=O)Nc1c(F)cc([N+](=O)[O-])cc1C#CC(C)(C)C>>CC(C)(C)c1cc2cc([N+](=O)[O-])cc(F)c2[nH]1,,CN(C)C=O,,O,CC(C)(C)[O-].[K+],test
US04230709,CCCCN=C=O.O=C(O)C1CCCN1>>CCCCN1C(=O)C2CCCN2C1=O,,O,,[Na+].[OH-],,test
US05260316,C=C(C)CCl.O=C1c2ccc(O)cc2CCN1CCCc1ccccc1>>C=C(C)COc1ccc2c(c1)CCN(CCCc1ccccc1)C2=O,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050020684A1,CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@@H](O)C1.Oc1ccc(-c2ccccc2)cc1>>CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@H](Oc2ccc(-c3ccccc3)cc2)C1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040110763A1,CCOC(=O)COc1ccn2nc(-c3ccccc3)c(-c3ccc(=O)n(C(C)C)n3)c2c1>>CC(C)n1nc(-c2c(-c3ccccc3)nn3ccc(OCC(=O)O)cc23)ccc1=O,,CCO,,[Na+].[OH-],,test
US20070173488A1,CCN.O=C(O)c1ccc(=O)n(-c2n[nH]c3nc(NC(=O)C4CC4)sc23)c1>>CCNC(=O)c1ccc(=O)n(-c2n[nH]c3nc(NC(=O)C4CC4)sc23)c1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090247561A1,BrCc1ccccc1.CN(C)C1(c2ccccc2)CCC(=O)CC1>>CN(C)C1(c2ccccc2)CCC(=O)C(Cc2ccccc2)C1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20100093730A1,NC(c1ccccc1)C1CC1.O=C(O)CN1CCC(c2ccccc2)(c2ccccc2)C1=O>>O=C(CN1CCC(c2ccccc2)(c2ccccc2)C1=O)NC(c1ccccc1)C1CC1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20040167127A1,CNOC.Cc1cccc(C(=O)O)c1F>>CON(C)C(=O)c1cccc(C)c1F,,c1ccncc1,,Cl,O=C(Cl)C(=O)Cl,test
US04035495,CC(=O)C(=O)N(C)C.Oc1ccccc1-n1cccc1>>CN(C)C(=O)C1(C)Oc2ccccc2-n2cccc21,,c1ccccc1,,O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3,,test
US20100298336A1,Cc1cc(O)nc(S)n1.Clc1nc2ccccn2c1CBr>>Cc1cc(O)nc(SCc2c(Cl)nc3ccccn23)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160102094A1,CC(C)(C)OC(=O)N[C@H](CO)Cc1ccccc1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)CN1C(=O)c2ccccc2C1=O,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20010006969A1,Cc1csc2c(Cl)nc(Cl)nc12.NC(CO)CO>>Cc1csc2c(NC(CO)CO)nc(Cl)nc12,,CN(C)C=O,,,,test
US20100216746A1,COC(=O)c1[nH]c(C(=O)O)cc1Cl.O=C(Cl)C(=O)Cl>>COC(=O)c1[nH]c(C(=O)Cl)cc1Cl,,ClCCl,,CN(C)C=O,,test
US20110183998A1,CC(C)Oc1ccc(C(=O)c2ccc(O)cc2)cn1>>CC(C)Oc1ccc(Cc2ccc(O)cc2)cn1,,C1CCOC1,,CC[SiH](CC)CC,,test
US20070238737A1,Nc1cccc(Br)n1.O=S(=O)(Cl)c1ccc(Br)c(F)c1>>O=S(=O)(Nc1cccc(Br)n1)c1ccc(Br)c(F)c1,,ClCCl,c1ccncc1,,,test
US04387105,CCCCNCCCC.O=C([O-])Nc1cccc(Br)c1>>CCCCN(CCCC)C(=O)Nc1cccc(Br)c1,,CCCCCC,,C1CCOC1,,test
US06797726B1,CCN(CC)CCOCCc1cccc2ccccc12.O=C(O)C(=O)O>>CCN(CC)CCOCCc1cccc2ccccc12.O=C(O)C(=O)O,,CCOC(C)=O,,,,test
US20160031830A1,CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1C1=CCN(C(=O)OC(C)(C)C)CC1>>CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1C1=CCNCC1,,O=C(O)C(F)(F)F,,,,test
US20100003191A1,O=C1/C(=C/c2ccc(O)cc2)Oc2ccc(I)cc21.OCCCl>>O=C1/C(=C/c2ccc(OCCO)cc2)Oc2ccc(I)cc21,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050148627A1,CCOC(=O)/C=C/C(F)(F)F.O=Cc1cc(I)cc(Cl)c1O>>CCOC(=O)C1=Cc2cc(I)cc(Cl)c2OC1C(F)(F)F,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100249085A1,CC(C)(C)OC(=O)N1CCC(COc2ccc(C#N)cc2)CC1.NO>>CC(C)(C)OC(=O)N1CCC(COc2ccc(C(N)=NO)cc2)CC1,,CCO,,CCN(CC)CC,Cl,test
US20100029737A1,COC(=O)c1cc2c([nH]1)CC(F)(F)C2OC>>COC1c2cc(C(=O)O)[nH]c2CC1(F)F,,CCOC(C)=O,,,,test
US20150352219A1,C=CCOC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)O.Nc1ccc(CO)cc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>C=CCOC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)O.Nc1ccc(COC(=O)Oc2ccc([N+](=O)[O-])cc2)cc1,,C1CCOC1,CCOC(C)=O,c1ccncc1,,test
US06355653B1,Nc1cc(Br)cc2nc(-c3ccco3)nn12.Oc1cccc2c1CCCC2>>Nc1cc(Oc2cccc3c2CCCC3)cc2nc(-c3ccco3)nn12,,CN1CCCC1=O,,,,test
US20130330327A1,C[C@H]1CN(C[C@@](C)(O)COc2ccc3c(c2O)N=C(NC(=O)c2cnc(N)nc2)N2CCN=C32)C[C@@H](C)O1.Fc1ccc(CCBr)cc1>>C[C@H]1CN(C[C@@](C)(O)COc2ccc3c(c2OCCc2ccc(F)cc2)N=C(NC(=O)c2cnc(N)nc2)N2CCN=C32)C[C@@H](C)O1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030078271A1,CCOC(=O)c1ccc(CN2C(=O)C(=O)c3ccccc32)o1.Nc1cccc(C(F)(F)F)c1>>CCOC(=O)c1ccc(CN2C(=O)/C(=N\c3cccc(C(F)(F)F)c3)c3ccccc32)o1,,ClC(Cl)Cl,,,,test
US20070167413A1,CS(=O)(=O)c1ccc(-c2nc(C(F)(F)F)nc(O)c2-c2ccccc2)cc1.O=S(=O)(Cl)c1cccc2ccccc12>>CS(=O)(=O)c1ccc(-c2nc(C(F)(F)F)nc(OS(=O)(=O)c3cccc4ccccc34)c2-c2ccccc2)cc1,,ClCCl,,c1ccncc1,,test
US20100197634A1,CC(C)(C)[Si](C)(C)Cl.Cc1ccc(CO)cc1N>>Cc1ccc(CO[Si](C)(C)C(C)(C)C)cc1N,,CCOC(C)=O,CN(C)C=O,O,c1c[nH]cn1,test
US20070032487A1,CCc1cnc(CCNC(=O)Nc2nc(C)c(-c3cc(C)nc(S(C)(=O)=O)n3)s2)o1.CNC>>CCc1cnc(CCNC(=O)Nc2nc(C)c(-c3cc(C)nc(N(C)C)n3)s2)o1,,CN(C)C=O,,,,test
US20060276465A1,CCCCN1CCN(c2cc3c(cc2C2=CC(C)(C)CC(C)(C)C2)OCO3)CC1.Cl>>CCCCN1CCN(c2cc3c(cc2C2CC(C)(C)CC(C)(C)C2)OCO3)CC1.Cl,[Pd],C1CCOC1,,CO,,test
US04002640,CCOCCl.Nc1cc(S)ccc1[N+](=O)[O-]>>CCOCSc1ccc([N+](=O)[O-])c(N)c1,,O,,CN(C)C=O,[H-].[Na+],test
US20030229051A1,C/C=C/C(=O)Cl.Nc1ccc2c(Nc3cccc(Br)c3)ncnc2c1>>CC=CC(=O)Nc1ccc2c(Nc3cccc(Br)c3)ncnc2c1,,C1CCOC1,,,,test
US20070066588A1,C1CCNC1.O=C1CC(c2nc3ccc(Br)cc3s2)C1>>Brc1ccc2nc([C@@H]3C[C@H](N4CCCC4)C3)sc2c1,,CO,,[BH3-]C#N.[Na+],,test
US20070179136A1,CC(C)(C)OC(=O)N1CCC(c2ccc(-c3nc4c(C(N)=O)cc(F)cc4[nH]3)cc2)CC1.O=C(O)C(F)(F)F>>NC(=O)c1cc(F)cc2[nH]c(-c3ccc(C4CCNCC4)cc3)nc12.O=C(O)C(F)(F)F,,ClCCl,,,,test
US05084572,CC(C)N1CC2CNCC(C2)C1.O=S(=O)(Cl)c1ccccc1>>CC(C)N1CC2CC(C1)CN(S(=O)(=O)c1ccccc1)C2,,ClCCl,O,CO,[Na+].[OH-],test
US20110028466A1,C=C(CO)CO[Si](C)(C)C(C)(C)C.II>>C=C(CI)CO[Si](C)(C)C(C)(C)C,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04251528,CCOC(=O)Cc1nn(Cc2ccc(Br)c(Cl)c2)c(=O)c2ccccc12.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CCOC(=O)Cc1nn(Cc2ccc(Br)c(Cl)c2)c(=S)c2ccccc12,,Cc1ccccc1C,,CCOC(C)=O,,test
US05053414,Br[Mg]c1ccccc1.CN(Cc1ccccc1)C(=O)CCC(=O)N1CCC[C@H]1C=O>>CN(Cc1ccccc1)C(=O)CCC(=O)N1CCC[C@H]1C(O)c1ccccc1,,C1CCOC1,,[Cl-].[NH4+],,test
US20150105403A1,CCOC(=O)/C=C/c1ccc(/C(=C(\c2ccc(F)cc2Cl)C2CCC2)c2coc3c(OC)cccc23)cc1>>CCOC(=O)/C=C/c1ccc(/C(=C(\c2ccc(F)cc2Cl)C2CCC2)c2coc3c(O)cccc23)cc1,,ClCCl,,BrB(Br)Br,,test
US20160075720A1,C[C@@H]1CNc2c(sc3ccc4nc(S)ccc4c23)C(=O)N1.Fc1cc(F)ncn1>>C[C@@H]1CNc2c(sc3ccc4nc(Sc5cc(F)ncn5)ccc4c23)C(=O)N1,,CN(C)C=O,,[H-].[Na+],,test
US20010001799A1,CCc1cc(Br)ccc1OC.CN(C)C=O>>CCc1cc(C=O)ccc1OC,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20060016752A1,CC(C)(C)OC(=O)CON1C(=O)c2ccccc2C1=O>>O=C(O)CON1C(=O)c2ccccc2C1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140296245A1,COc1ccc(CNc2nncs2)c(OC)c1.O=S(=O)(Cl)c1cc(F)c(F)cc1F>>COc1ccc(CN(c2nncs2)S(=O)(=O)c2cc(F)c(F)cc2F)c(OC)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20110301155A1,COCCl.O=C1c2ccccc2C(=O)N1c1n[nH]c2c(OCCc3ccccn3)cc(-c3ncccc3Cl)cc12>>COCn1nc(N2C(=O)c3ccccc3C2=O)c2cc(-c3ncccc3Cl)cc(OCCc3ccccn3)c21,,O,,CN(C)C=O,[H-].[Na+],test
US20150299189A1,Cn1cc(C2CCCCC2)c2cc([N+](=O)[O-])ccc21>>Cn1cc(C2CCCCC2)c2cc(N)ccc21,[Pd],CO,,,,test
US20100240658A1,CO.COC(=O)c1cc(F)c(C#N)cc1Cl>>COc1cc(C(=O)O)c(Cl)cc1C#N,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20160272632A1,N#C/C=C1\CCCOC1.Nc1n[nH]c2ccnc(OCc3ccccc3)c12>>N#CCC1(n2nc(N)c3c(OCc4ccccc4)nccc32)CCCOC1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20090247567A1,CN(C)[C@H]1CCNC1.O=C(O)c1ccc2c(c1)-c1sc(-c3ncnn3-c3ccc(F)cc3F)cc1CCO2>>CN(C)[C@H]1CCN(C(=O)c2ccc3c(c2)-c2sc(-c4ncnn4-c4ccc(F)cc4F)cc2CCO3)C1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05093328,CC(=O)OC(C)=O.CC(C)(C)[Si](C)(C)O[C@@H]1C[C@@H](CO)N(C(=O)OCc2ccccc2)C1>>CC(=O)OC[C@@H]1C[C@@H](O[Si](C)(C)C(C)(C)C)CN1C(=O)OCc1ccccc1,,CCOC(C)=O,c1ccncc1,,,test
US05364866,COc1cc(C(C)=O)ccc1O.ClC/C=C\CCl>>COc1cc(C(C)=O)ccc1OC/C=C\CCl,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130131050A1,CCCSc1nc2[nH]c(=O)ccc2c(=O)n1-c1ccc(OCC(F)(F)F)cc1.CSCCCO>>CSCCCOc1nc2[nH]c(=O)ccc2c(=O)n1-c1ccc(OCC(F)(F)F)cc1,,C1CCOC1,,O,[H-].[Na+],test
US20110009454A1,COc1cccc(CN)c1.Nc1ncccc1C(=O)O>>COc1cccc(CNC(=O)c2cccnc2N)c1,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20050277772A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1ccc2ccccc2c1-c1nnc(Cl)c2ccccc12>>O=S(=O)(Oc1ccc2ccccc2c1-c1nnc(Cl)c2ccccc12)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US20080242683A1,CC(C)(C)OC(=O)N1CC[C@@H](NC(=O)c2ccncc2)C1>>O=C(N[C@@H]1CCNC1)c1ccncc1,,CO,,Cl,,test
US20120208796A1,CN1C[C@@H]2C[C@H]1CN2c1ccc(N)c(C(N)=O)c1.COC(OC)OC>>CN1C[C@@H]2C[C@H]1CN2c1ccc2nc[nH]c(=O)c2c1,,CO,,C,O=C[O-].[NH4+],test
US20120214803A1,COc1ccc(C(=O)c2ccc3cccnc3c2[N+](=O)[O-])cc1>>COc1ccc(C(=O)c2ccc3cccnc3c2N)cc1,[Pd],C1CCOC1,,,,test
US20140080884A1,CN(C)/C=C1/CN(C(=O)OC(C)(C)C)CC1=O.NN>>CC(C)(C)OC(=O)N1CC2C=NNC2(O)C1,,Cc1ccccc1,,O,,test
US06080785,NCCNCCN.O=Cc1ccccc1>>NCCNCCNCc1ccccc1,,CO,,[BH4-].[Na+],,test
US05506256,CC(C)(C)OC(=O)N1CCC[C@H]1C1CO1.Oc1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@H]1C(O)COc1ccccc1,,CO,,C[O-].[Na+],,test
US20160016936A1,Cc1cc(-c2cn(CCN3CCC3)c([C@H]3CCNC[C@H]3F)n2)ccc1F.N#Cc1c(N)ncnc1Cl>>Cc1cc(-c2cn(CCN3CCC3)c([C@H]3CCN(c4ncnc(N)c4C#N)C[C@H]3F)n2)ccc1F,,CC#N,,CCN(C(C)C)C(C)C,,test
US05521160,COC(=O)c1ccc(C(=O)N(C)c2ccc(C(=O)OC)cc2)cc1>>CN(C(=O)c1ccc(C(=O)O)cc1)c1ccc(C(=O)O)cc1,,CC#N,,Cl,[Na+].[OH-],test
US05710171,C1CCOC1.O=Cc1ccc(Oc2ccccc2)cc1.[Li]CCCC>>OCCCCCc1ccc(Oc2ccccc2)cc1,,C1CCOC1,CCCCCC,CCOC(C)=O,O=C([O-])O.[Na+],test
US20020094935A1,BrBr.COC(=O)c1sccc1O>>COC(=O)c1scc(Br)c1O,,CC(=O)O,,O=S([O-])O.[Na+],,test
US20060041130A1,Cc1ccc(C(=O)N(CCCNC(=O)OC(C)(C)C)C(c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1>>Cc1ccc(C(=O)N(CCCN)[C@@H](c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20130040978A1,CC1(C)CCc2cc(Br)cc(Cl)c2O1.CN(C)C=O>>CC1(C)CCc2cc(C=O)cc(Cl)c2O1,,C1CCOC1,,[Li]CCCC,,test
US20140005221A1,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc2cc[nH]c2c1>>COC(=O)/C=C/c1ccc2cc[nH]c2c1,,C1CCOC1,,,,test
US20050192300A1,CS(=O)(=O)Cl.Cc1nc(C)c(-c2ccnc(Nc3ccc(N4CCNCC4)cc3)n2)s1>>Cc1nc(C)c(-c2ccnc(Nc3ccc(N4CCN(S(C)(=O)=O)CC4)cc3)n2)s1,,ClCCl,,CCN(CC)CC,,test
US20030083357A1,Cc1cc2c(cc1-c1cc(CO)ccc1OC(F)(F)F)C(C)(C)CCC2(C)C.O=Cc1ccc(F)cc1>>Cc1cc2c(cc1-c1cc(COc3ccc(C=O)cc3)ccc1OC(F)(F)F)C(C)(C)CCC2(C)C,,CCOC(C)=O,CN(C)C=O,[H][H],[H-].[Na+],test
US20050245432A1,BrCc1ccccc1.CN(C(=O)OCc1ccccc1)[C@@H](CCCCO)C(=O)O>>CN(C(=O)OCc1ccccc1)[C@@H](CCCCO)C(=O)OCc1ccccc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100317675A1,C[Sn](C)(C)c1ccc2nc(C(=O)Nc3ccccc3)cn2c1.Nc1cccc(Br)n1>>Nc1cccc(-c2ccc3nc(C(=O)Nc4ccccc4)cn3c2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US20150045560A1,COCOc1c(Br)cc2c(C)c(OCOC)c(Br)cc2c1C>>Cc1c(O)c(Br)cc2c(C)c(O)c(Br)cc12,,CO,ClCCl,Cl,O,test
US20150038528A1,CC(C)(C)OC(=O)C(C)(C)CNC(=O)c1nc(C#N)c2cc(OC3CCCCC3)ccc2c1O>>CC(C)(CNC(=O)c1nc(C#N)c2cc(OC3CCCCC3)ccc2c1O)C(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US05905071,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.CCCCCCCCCCCCCCN(C(=O)CCCCCCCCCCC)[C@]1(N)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1C(=O)CN>>CCCCCCCCCCCCCCN(C(=O)CCCCCCCCCCC)[C@]1(N)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1C(=O)CNC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C,,ClCCl,,,,test
US20150210720A1,CCOC(=O)C1(O)COC2=C1C(=O)C(C)(C)OC2>>CCOC(=O)c1coc2c1C(=O)C(C)(C)OC2,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20160024053A1,COC(=O)c1ccc2c(SC)cn(-c3ncc(-c4ccccn4)cn3)c2c1>>CSc1cn(-c2ncc(-c3ccccn3)cn2)c2cc(C(=O)O)ccc12,,C1CCOC1,O,[Li+].[OH-],,test
US20120264748A1,CCOC(=O)C1CCN(C(=O)OC(C)(C)C)CC1.N#CCCBr>>CCOC(=O)C1(CCC#N)CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20160021883A1,CC(C)n1cnnc1-c1ccccc1N.FC(F)(F)Oc1ccc(-n2cnc(-c3ccc(N=C=S)cc3)n2)cc1>>CC(C)n1cnnc1-c1ccccc1NC(=S)Nc1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1,,CC(C)O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050070549A1,COC1(c2ccc(Cl)cc2)CCN(C(=O)OC(C)(C)C)CC1=O.C[Mg]Br>>COC1(c2ccc(Cl)cc2)CCN(C(=O)OC(C)(C)C)CC1(C)O,,C1CCOC1,,,,test
US20130040997A1,Cc1ncc(CCC(=O)O)c(C(=O)O)c1O>>Cc1ncc(C=CC(=O)O)c(C=O)c1O,,CO,,Cl,,test
US20110230428A1,CON.O=C(CCc1nn[nH]n1)c1ccc(Cl)c(Cl)c1>>CON=C(CCc1nn[nH]n1)c1ccc(Cl)c(Cl)c1,,O,,Cl,c1ccncc1,test
US20120058989A1,CCOC(=O)c1cn(C2CC2)c2c(CCC[C@@H]3C[C@@H](OCc4ccc(OC)cc4)CN3)c(F)c(F)cc2c1=O>>CCOC(=O)c1cn(C2CC2)c2c(CCC[C@@H]3C[C@@H](O)CN3)c(F)c(F)cc2c1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140336377A1,CI.O=C(O)c1cccc(OCC(F)(F)F)n1>>COC(=O)c1cccc(OCC(F)(F)F)n1,,CC(=O)N(C)C,,O,O=C([O-])[O-].[K+].[K+],test
US20060128793A1,CNC(C)(C)C.COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CC[C@H](O)[C@@]2(C)C[C@H]1OC(C)=O>>COCC1OC(=O)C(=CN(C)C(C)(C)C)C2=C(O)C(=O)C3=C(C(OC(C)=O)CC4(C)C(O)CCC34)C21C,,ClCCl,,,,test
US20160122344A1,C=CCB1OC(C)(C)C(C)(C)O1.COCCOc1cc(Br)ccc1Cl>>C=CCc1ccc(Cl)c(OCCOC)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,[Cs+].[F-],,test
US20060100201A1,CC1CCN(c2cc(Cl)c(F)cc2[N+](=O)[O-])CC1.CN1CCNCC1>>CC1CCN(c2cc(N3CCN(C)CC3)c(F)cc2[N+](=O)[O-])CC1,,CO,ClCCl,,,test
US20030119889A1,CCOC(=O)C(=O)Cl.CNC(=S)Nc1cc(Cl)ccc1C>>Cc1ccc(Cl)cc1N1C(=O)C(=O)N(C)C1=S,,ClC(Cl)Cl,,,,test
US06046201,CC(C)(C)OC(=O)NCCCCCCCCCCCCI.Cl>>Cl.NCCCCCCCCCCCCI,,CCOC(C)=O,,,,test
US20060142576A1,Cc1nc(-c2ccccc2)nc(-c2ccc(Cl)cc2Cl)c1CO>>Cc1nc(-c2ccccc2)nc(-c2ccc(Cl)cc2Cl)c1C=O,,CCOC(C)=O,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20140303153A1,COC(=O)c1c(CO)cn(Cc2ccc(OC)cc2)c(=O)c1Cl.O=S(Cl)Cl>>COC(=O)c1c(CCl)cn(Cc2ccc(OC)cc2)c(=O)c1Cl,,ClC(Cl)Cl,,CN(C)C=O,,test
US05135932,CO.COCCOCc1ccc(OCC2CO2)cc1.ClCCl>>c1ccc2c(OCC3CO3)cccc2c1,,CO,ClCCl,,,test
US20040142993A1,COC(=O)c1ccccc1Nc1ccc(C(F)(F)F)cc1[N+](=O)[O-]>>COC(=O)c1ccccc1Nc1ccc(C(F)(F)F)cc1N,Cl[Ni]Cl,C1CCOC1,,CO,[BH4-].[Na+],test
US20090186830A1,CC(C)(C)O.O=C(NC1CCC(C(=O)O)CC1)OCc1ccccc1>>CC(C)(C)OC(=O)C1CCC(NC(=O)OCc2ccccc2)CC1,CN(C)c1ccncc1,CN(C)C=O,ClCCl,CC(C)N=C=NC(C)C,,test
US20140170064A1,CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCN(CC(=O)NCC(=O)O)C(=O)Cc2ccc(O)cc2)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1.NCCN1C(=O)C=CC1=O>>CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCN(CC(=O)NCC(=O)NCCN2C(=O)C=CC2=O)C(=O)Cc2ccc(O)cc2)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1,,CC#N,,CCN=C=NCCCN(C)C,Cl,test
US20160075692A1,F[C@H]1CCCNC1.O=C(O)CN1CCN(c2cccc3c2cnn3-c2ccccc2F)C1=O>>O=C(CN1CCN(c2cccc3c2cnn3-c2ccccc2F)C1=O)N1CCC[C@H](F)C1,,CN(C)C=O,,Cl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150344466A1,CCOC(=O)c1cc(Cc2ccc(F)c(F)c2)on1>>O=C(O)c1cc(Cc2ccc(F)c(F)c2)on1,,O,,CCO,[Na+].[OH-],test
US20140171420A1,CC(C)c1c(N2CCC(n3nc(C#N)c4c(N)ncnc43)C2=O)cnn1-c1ccc(F)cc1.NCCN>>CC(C)c1c(N2CCC(n3nc(C4=NCCN4)c4c(N)ncnc43)C2=O)cnn1-c1ccc(F)cc1,,CC(=O)O,,CCO,,test
US20030158163A1,C[C@@H]1CC2C3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]34O[C@H]4C[C@]2(C)[C@@]1(O)C(=O)O.O=C(Cl)c1ccco1>>C[C@@H]1CC2C3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]34O[C@H]4C[C@]2(C)[C@@]1(OC(=O)c1ccco1)C(=O)O,,c1ccncc1,,Cl,ClCCl,test
US20030134836A1,ClCCl.Nc1ccc(Cl)cc1.Nc1cccnc1C(=O)O.On1nnc2ccccc21>>O=C(Nc1ccc(Cl)cc1)c1ncccc1NCc1ccccc1,,ClCCl,,ClCCCl,,test
US20100204247A1,CC1(Cc2cc(F)cc(F)c2)C(=O)Nc2ccc(-c3cccc(C(F)(F)F)c3)cc21.Cn1cnc(CCl)n1>>Cn1cnc(CN2C(=O)C(C)(Cc3cc(F)cc(F)c3)c3cc(-c4cccc(C(F)(F)F)c4)ccc32)n1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US04415652,C=CCN.CC(=O)O.Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1>>C=CCN1C(=O)C=CC1=O,,O,,,,test
US09181279B2,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1(C)C[C@H](CO)NC1=O>>CC1(C)C[C@H](CO)N(C(=O)OC(C)(C)C)C1,,C1CCOC1,O,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20100196321A1,O=C(Cl)C(=O)Cl.O=C(O)c1nc(C(F)(F)F)cs1>>O=C(Cl)c1nc(C(F)(F)F)cs1,,ClCCl,,,,test
US20120165343A1,COC(=O)c1ccc(F)nc1.NC(c1cnc(-c2ccc(C(F)(F)F)cc2)nc1)C1CCCCC1>>COC(=O)c1ccc(NC(c2cnc(-c3ccc(C(F)(F)F)cc3)nc2)C2CCCCC2)nc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20160185745A1,CC(=O)C#CC(=O)OC(C)(C)C.CC(C)(C)C(=O)Oc1coc(O[Si](C)(C)C(C)(C)C)c1>>CC(=O)C1=C(C(=O)OC(C)(C)C)C2OC1(O[Si](C)(C)C(C)(C)C)C=C2OC(=O)C(C)(C)C,,C1CCOC1,,,,test
US20130324530A1,CS(=O)(=O)Cl.O[C@@H]1CC[C@@H](Nc2cc(-c3cc(NCC4CCOCC4)cnc3Cl)c(Cl)cn2)CC1>>CS(=O)(=O)O[C@@H]1CC[C@@H](Nc2cc(-c3cc(NCC4CCOCC4)cnc3Cl)c(Cl)cn2)CC1,,CCOC(C)=O,,ClCCl,,test
US20120288794A1,C=C(C)C(=O)Cl.CC1(C)OCC(O)CO1>>C=C(C)C(=O)OC1COC(C)(C)OC1,,CCN(CC)CC,,ClCCl,,test
US20160083400A1,Cc1ccc(C(CO)Nc2nc(=O)c3cnc(C(C)C)n3[nH]2)cc1>>Cc1ccc(C2CN3C(=O)c4cnc(C(C)C)n4NC3=N2)cc1,,ClCCl,,CS(=O)(=O)Cl,,test
US05523302,CC(C)(C)OC(=O)NCCOc1cccc(C(=O)C=Cc2ccc(OCC(=O)O)cc2)c1.Cl>>Cl.NCCOc1cccc(C(=O)/C=C/c2ccc(OCC(=O)O)cc2)c1,,C1COCCO1,,CCOCC,,test
US20070078121A1,CC(=O)Cl.CO.O=C(O)[C@@H]1Cc2ccc([N+](=O)[O-])cc2CN1>>COC(=O)[C@@H]1Cc2ccc([N+](=O)[O-])cc2CN1.Cl,,CO,,,,test
US20120202785A1,C[C@@H](COc1c(F)ccc([N+](=O)[O-])c1F)NC(=O)OC(C)(C)C>>C[C@H]1COc2c(F)ccc([N+](=O)[O-])c2N1,,ClCCl,,Cc1ccccc1,O=C(O)C(F)(F)F,test
US04751328,O=[N+]([O-])c1cccc(C=NO)c1>>NCc1cccc(N)c1,,C1CCOC1,,,,test
US20090215780A1,CCOC(=O)C(CC(=O)c1ccc(-c2ccc([N+](=O)[O-])cc2)cc1)C(=O)OCC>>CCOC(=O)C(CC(=O)c1ccc(-c2ccc(N)cc2)cc1)C(=O)OCC,[Fe],CCO,O,Cl,,test
US20120135990A1,CC(C)(C)OC(=O)N1CC(Oc2ccc(F)c(F)c2)C2C1CCN2C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N1CC(Oc2ccc(F)c(F)c2)C2NCCC21,,CCOC(C)=O,CO,,,test
US04031069,CC(C)(C)OC(=O)N[C@@H](COCc1ccccc1)C(=O)O.CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O.CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O.C[C@@H](NC(=O)OC(C)(C)C)C(=O)O>>C[C@@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)[C@H](COCc1ccccc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)O,,CCN(CC)CC,CO,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20030134883A1,CC[Si](CC)(CC)OC(C(C)=Cc1csc(C)n1)C(C)CO.II>>CC[Si](CC)(CC)OC(C(C)=Cc1csc(C)n1)C(C)CI,,CC#N,CCOCC,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050048108A1,CCC(=O)CC.OCCC(O)CO>>CCC1(CC)OCC(CCO)O1,,C1CCOC1,,Cc1ccccc1S(=O)(=O)O,,test
US20130274287A1,CCC(=O)Cl.OC1CCc2c(-c3ccc(C(F)(F)F)c(F)c3)cncc21>>CCC(=O)OC1CCc2c(-c3ccc(C(F)(F)F)c(F)c3)cncc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,[Na+].[OH-],test
US20100278833A1,CN(C)CCN1CCNCC1.C[C@@H](Oc1cc(-n2cnc3cnc(COS(C)(=O)=O)cc32)sc1C(N)=O)c1ccccc1F>>C[C@@H](Oc1cc(-n2cnc3cnc(CN4CCN(CCN(C)C)CC4)cc32)sc1C(N)=O)c1ccccc1F,,ClCCl,,,,test
US05834401,CCOC(=O)C(C)(C)NCCCCl.O=C=Nc1ccccc1>>CCOC(=O)C(C)(C)N(CCCCl)C(=O)Nc1ccccc1,,Cc1ccccc1,,O,,test
US20100190814A1,CCC(=O)OC(=O)CC.CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)NS(C)(=O)=O>>CCC(=O)N1C(=O)C2(c3ccc(Cl)cc31)C(c1cc(Cl)ccc1OC(CC)(CC)C(=O)NS(C)(=O)=O)CC(=O)NC2c1cc(F)ccc1C,CN(C)c1ccncc1,C1CCOC1,,,,test
US05607958,COc1cccc(OC)c1-c1cc(C(=O)Cl)nn1-c1cccc2cnccc12.NC1(C(=O)O)C2CC3CC(C2)CC1C3>>COc1cccc(OC)c1-c1cc(C(=O)NC2(C(=O)O)C3CC4CC(C3)CC2C4)nn1-c1cccc2cnccc12,,ClCCl,c1ccncc1,,,test
US04626542,C1=Cc2ccccc2C(C2CCNCC2)c2ccccc21.O=C1CCCCC1>>C1=Cc2ccccc2C(C2CCN(C3CCCCC3)CC2)c2ccccc21,,CO,,[Al],,test
US06498172B1,COC(=O)CCc1cccc(CNCc2cc3ccccc3o2)c1.O=S(=O)(Cl)c1ccc(F)cc1>>COC(=O)CCc1cccc(CN(Cc2cc3ccccc3o2)S(=O)(=O)c2ccc(F)cc2)c1,,CCN(CC)CC,,,,test
US20090137580A1,Cn1ccc2ncnc(Oc3ccc(N)c(Cl)c3)c21.O=C=Nc1cccc(C(F)(F)F)c1>>Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(Cl)c3)c21,,C1CCOC1,O,CCN(CC)CC,,test
US20110117073A1,CC(C)(C)OC(=O)N1CCC(Sc2nc(Cl)cc(Nc3ncc(C#N)s3)n2)CC1.CN1CCNCC1>>CN1CCN(c2cc(Nc3ncc(C#N)s3)nc(SC3CCN(C(=O)OC(C)(C)C)CC3)n2)CC1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US05929117,Br[Mg]c1ccccc1.COc1ccc(C(=O)N(C)OC)cc1OC1CCCC1>>COc1ccc(C(=O)c2ccccc2)cc1OC1CCCC1,,CCOCC,,CC#N,,test
US20080058321A1,CCOC(=N)c1ccc(S)c(Br)c1.O=S(=O)(O)O>>CCOC(=O)c1ccc(S)c(Br)c1,[Zn],CCO,,O,,test
US20160229864A1,CC(C)(C)OC(=O)N1CCC2(CC1)CO2.O=c1[nH]cnc2c(-c3ccc(F)cc3)csc12>>CC(C)(C)OC(=O)N1CCC(O)(Cn2cnc3c(-c4ccc(F)cc4)csc3c2=O)CC1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050233988A1,CC(=O)OC[C@H]1O[C@@H](c2ccc(Cl)c(Cc3ccc(-c4ccc(N)cc4)s3)c2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.CS(=O)(=O)Cl>>CC(=O)OC[C@H]1O[C@@H](c2ccc(Cl)c(Cc3ccc(-c4ccc(NS(C)(=O)=O)cc4)s3)c2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,ClCCl,,Cl,c1ccncc1,test
US20110294781A1,Clc1cc(Cl)n2nc(-c3ccccc3)cc2n1.OC1CNC1>>OC1CN(c2cc(Cl)nc3cc(-c4ccccc4)nn23)C1,,C1COCCO1,,Cl,O=C([O-])[O-].[K+].[K+],test
US06777428B1,C[N-]c1cccc(C(=O)C2CCN(C)CC2)c1>>CN1CCC(C(=O)c2cccc(N)c2)CC1,,Cl,,,,test
US20100168082A1,c1ccc(COCc2cc(Oc3ccc4[nH]ccc4c3)ncn2)cc1>>c1ccc(COCc2cc(Oc3ccc4c(c3)CCN4)ncn2)cc1,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20160237045A1,CC(C)Oc1ccccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nc(C(F)(F)C(F)(F)C(=O)O)n[nH]3)cc2)cc1.Cl>>CC(C)Oc1ccccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3nc(C(F)(F)C(F)(F)C(=O)O)n[nH]3)cc2)cc1.Cl,,C1COCCO1,,CC#N,,test
US20080096860A1,COc1cc(Cl)nc(SCc2cccc(F)c2F)n1.NS(=O)(=O)N1CCNC(=O)C1>>COc1cc(NS(=O)(=O)N2CCNC(=O)C2)nc(SCc2cccc(F)c2F)n1,,CCOC(C)=O,,,,test
US20080027049A1,CC(C)(C)CC(=O)Cl.Nc1ccc2oc3c(c2c1)CCCCCC3>>CC(C)(C)CC(=O)Nc1ccc2oc3c(c2c1)CCCCCC3,,c1ccncc1,,,,test
US04005208,CCN1CCCC(=O)C1.CN>>CCN1CCCC(NC)C1,O=[Pt]=O,CO,,[H][H],,test
US20030000129A1,C=CCOc1ccccc1N.CC1(C)CC(O)CC(C)(C)N1O>>CC1(C)CCCC(C)(C)N1OCC1COc2ccccc21,,Clc1ccccc1,,CC(C)(C)ON=O,,test
US20070124152A1,CCOCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCN)c1=O.COC(=O)Cl>>CCOCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCNC(=O)OC)c1=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05300660,CCBr.NC(=O)[C@@H]1CCCN1>>CCN1CCC[C@H]1C(N)=O,,Cc1ccccc1,,CCN(CC)CC,CCO,test
US20070213355A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(CCNC2CC2)cc1>>CC(C)(C)OC(=O)N(CCc1ccc([N+](=O)[O-])cc1)C1CC1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20100273782A1,CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2cc([N+](=O)[O-])ccc2Oc2cc(Cl)ccc2Cl)CC1>>O=[N+]([O-])c1ccc(Oc2cc(Cl)ccc2Cl)c(S(=O)(=O)N2CCNCC2)c1,,C1COCCO1,ClCCl,CCOC(C)=O,Cl,test
US04550105,CN1CN(S[C@@H]2NC(=O)[C@H]2NC(c2ccccc2)(c2ccccc2)c2ccccc2)N=N1.CON=C(C(=O)O)c1csc(NC(=O)CCl)n1>>CON=C(C(=O)N[C@@H]1C(=O)N[C@H]1SN1CN(C)N=N1)c1csc(NC(=O)CCl)n1,,CC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100144787A1,CCc1nc2c(Cl)ccc(OCC(=O)OC)c2c(OC(F)F)c1Cc1ccc(-n2cccn2)cc1>>CCc1nc2c(Cl)ccc(OCC(=O)O)c2c(OC(F)F)c1Cc1ccc(-n2cccn2)cc1,,C1CCOC1,Cl,[Li+].[OH-],,test
US20100168131A1,CC(C)(C)OC(=O)N1C[C@H]2C[C@H]2C[C@H]1CN1C(=O)c2ccccc2C1=O>>CC(C)(C)OC(=O)N1C[C@H]2C[C@H]2C[C@H]1CN,,CCO,,NN,,test
US20100048639A1,CCOC(=O)c1cc[nH]n1.N#Cc1ccc(CBr)cc1Br>>CCOC(=O)c1ccn(Cc2ccc(C#N)c(Br)c2)n1,,CCO,,CC(C)(C)[O-].[K+],,test
US20110306589A1,Brc1ccccn1.CN(C)C(=O)c1n[nH]cc1[N+](=O)[O-]>>CN(C)C(=O)c1nn(-c2ccccn2)cc1[N+](=O)[O-],O=[Cu-],CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080167307A1,CCCCCCCN(CCc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1)c1ncc(Br)cn1.CN1CCNCC1.O=C(O)C(F)(F)F>>CCCCCCCN(CCc1csc(SC(C)(C)C(=O)O)n1)c1ncc(N2CCN(C)CC2)cn1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20050215539A1,CC(O)(c1cccs1)c1cc(Br)ccc1NC(=O)CCl>>CC1(c2cccs2)OCC(=O)Nc2ccc(Br)cc21,,C1CCOC1,,CCOC(C)=O,[Cl-].[NH4+],test
US20110110889A1,CCCS(=O)(=O)Nc1ccc(F)c(C(=O)O)c1F.CCc1cc2cc(N)cnc2[nH]1>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]c(CC)cc3c2)c1F,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US04377576,C1CCNC1.C=CC(=O)Cl.O=C1Nc2ccccc2Nc2ccccc21>>O=C1Nc2ccccc2N(C(=O)CCN2CCCC2)c2ccccc21,,Cc1ccccc1,,CCO,,test
US20060079554A1,CC(C)CN(Cc1ccccc1C(F)(F)F)C1CCNCC1.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>CC(C)CN(Cc1ccccc1C(F)(F)F)C1CCNCC1.O=C(O)[C@H](O)[C@@H](O)C(=O)O,,CC(C)O,,,,test
US20090131458A1,Clc1nc(Cl)c2ncn(CC3CCOCC3)c2n1.N>>Nc1nc(Cl)nc2c1ncn2CC1CCOCC1,,CC(C)O,,,,test
US04421914,CCOC(=O)C(Br)C(=O)OCC.CNC1CCCCC1>>CCOC(=O)C(C(=O)OCC)N(C)C1CCCCC1,,Cc1ccccc1,,CCN(CC)CC,,test
US20110130380A1,CC1(C)CC(CNc2nc(O)ccc2F)CCO1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC1(C)CC(CNc2nc(OS(=O)(=O)C(F)(F)F)ccc2F)CCO1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20030181496A1,OC(c1cnc2ccccc2c1)c1ccc[nH]1>>c1c[nH]c(Cc2cnc3ccccc3c2)c1,,CC(C)O,,O,[BH4-].[Na+],test
US20100331297A1,CCN=C=O.Nc1ncnc2c1c(Sc1cccc(Cl)c1)nn2C1CNC1>>CCNC(=O)N1CC(n2nc(Sc3cccc(Cl)c3)c3c(N)ncnc32)C1,,CN(C)C=O,O,c1ccncc1,,test
US05792767,CCOC(=O)c1ccccc1N.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCOC(=O)c1ccccc1N=C=O,,Cc1ccccc1,,,,test
US20120214837A1,CCCc1nc(O)cc2cc(OC)c(OC)cc12.CNc1nc2ccc(C)cc2cc1CCl.Cl.Cl>>CCCc1nc(O)c(Cc2cc3cc(C)ccc3nc2NC)c2cc(OC)c(OC)cc12.Cl.Cl,,Cc1ccccc1,,CO,[K+].[OH-],test
US20140221311A1,CNS(=O)(=O)c1ccccc1-c1ccc(-c2cnc3[nH]cc(C=O)c3c2)c(F)c1>>CNS(=O)(=O)c1ccccc1-c1ccc(-c2cnc3[nH]cc(CO)c3c2)c(F)c1,,CO,,[BH4-].[Na+],,test
US20060154920A1,C=O.NCCN1c2ccccc2C[C@H]2CCC[C@H]21>>c1cc2c3c(c1)C[C@@H]1CCC[C@H]1N3CCNC2,,CCO,,O=C(O)C(F)(F)F,,test
US04628057,CCOC(=O)[C@@H]1Cc2c([nH]c3ccccc23)CN1.ClCc1cccs1.S=C=S>>CCOC(=O)[C@@H]1Cc2c([nH]c3ccccc23)CN1C(=S)SCc1cccs1,,CCO,,CCN(CC)CC,,test
US05110955,CC(=O)OC/C=C(/C)CCc1c(C)c(O)c(C)c(C)c1O>>C=C[C@]1(C)CCc2c(C)c(O)c(C)c(C)c2O1,,CS(C)=O,O,,,test
US05656629,CCOC(=O)CC1NCCc2ccccc21>>CCOC(=O)CC1NCCc2ccccc21,,O,,Cl,O=C([O-])O.[Na+],test
US20060122168A1,O=C1Nc2cc(F)ccc2OC(Cc2ccccc2)C1N(Cc1ccccc1)Cc1ccccc1>>NC1C(=O)Nc2cc(F)ccc2OC1Cc1ccccc1,[Pd],CO,,,,test
US06002008,C1COCCN1.COc1cc2c(Nc3cc(O)c(Cl)cc3F)c(C#N)cnc2cc1OCCCl>>COc1cc2c(Nc3cc(O)c(Cl)cc3F)c(C#N)cnc2cc1OCCN1CCOCC1,,COCCOC,,[I-].[Na+],,test
US20040102450A1,CC(C)(C)OC(=O)CN1CCN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CC1=O>>O=C(O)CN1CCN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CC1=O,,ClCCl,O=C(O)C(F)(F)F,,,test
US05866564,CS(=O)(=O)O[C@@H]1C[C@@H](C(=O)O)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1.OCCN1CCNCC1>>CS(=O)(=O)O[C@H]1C[C@@H](C(=O)N2CCN(CCO)CC2)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1,,CC#N,,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20100324045A1,C[C@H](N)c1ccc(Br)cc1.O=C(CCCl)c1ccccc1>>C[C@H](NCCC(=O)c1ccccc1)c1ccc(Br)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04945090,CC(C)N.COCc1c(C(=O)O)ncc2[nH]c3cccc(Oc4ccc(Cl)cc4)c3c12>>COCc1c(C(=O)NC(C)C)ncc2[nH]c3cccc(Oc4ccc(Cl)cc4)c3c12,,CN(C)C=O,,O,O=C(n1ccnc1)n1ccnc1,test
US20080081810A1,COC(=O)C1Cc2ccc(OC)cc2N1C1(Cc2cccc(Cl)c2)C(=O)Nc2cc(Cl)ccc21>>COC(=O)c1cc2ccc(OC)cc2n1C1(Cc2cccc(Cl)c2)C(=O)Nc2cc(Cl)ccc21,,Cc1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20120289496A1,CNc1ncnc2[nH]ncc12.O=C1CCC(=O)N1I>>CNc1ncnc2[nH]nc(I)c12,,CN(C)C=O,,,,test
US20160237069A1,CC=O.Cc1cc(NC2CCCNC2)nc(NC(=N)Nc2ccc(Cl)c(Cl)c2)n1>>CCN1CCCC(Nc2cc(C)nc(NC(=N)Nc3ccc(Cl)c(Cl)c3)n2)C1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20060052247A1,CC(=O)O.CCCCCC.CCOC(C)=O>>O=C1CC(=O)C2C=CC1C2,[Zn],,,,,test
US04086238,CCN.COCC(Cl)C=O>>CCNC(C=O)COC,,Cc1ccccc1,,,,test
US20120225869A1,Cc1ccc(O)cc1.O=c1c2cnn(-c3ccccc3)c2nc(Cl)n1-c1ccc(Cl)cc1>>Cc1ccc(Oc2nc3c(cnn3-c3ccccc3)c(=O)n2-c2ccc(Cl)cc2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100184598A1,O=C1CCC(=O)N1Br.c1cnc2cc(-c3ccncc3)[nH]c2c1>>Brc1c(-c2ccncc2)[nH]c2cccnc12,,ClC(Cl)(Cl)Cl,,,,test
US20030092694A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@@H]1CNCCN1c1nccnc1OCCOc1cccnc1>>C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1c1nccnc1OCCOc1cccnc1,,C1COCCO1,,,,test
US05902803,CC(=O)OC(C)=O.NCc1ccc2c(c1)Cc1c-2[nH]c(=O)c2nccn12>>CC(=O)NCc1ccc2c(c1)Cc1c-2[nH]c(=O)c2nccn12,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20040254200A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.NC(=O)c1sc2c(ccc(=O)n2-c2ccccc2Cl)c1-c1ccccc1>>NC(=S)c1sc2c(ccc(=O)n2-c2ccccc2Cl)c1-c1ccccc1,,ClCCl,,Cc1ccccc1,,test
US20150344429A1,O=S(=O)(OCC(F)(F)F)C(F)(F)F.Oc1cc(Cl)ncc1Cl>>FC(F)(F)COc1cc(Cl)ncc1Cl,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120168732A1,COC(=O)c1ccc(I)cc1.NN>>NNC(=O)c1ccc(I)cc1,,CCO,,O,O,test
US05126366,Cc1c(O)ccc2c1OC(CN)CO2.O=[N+]([O-])c1cccc(OCCCBr)c1>>Cc1c(O)ccc2c1OC(CNCCCOc1cccc(N)c1)CO2,[Pd],CN(C)C=O,CO,CCN(C(C)C)C(C)C,Cl,test
US05643932,CC(N)=S.COc1ccc(C#N)cc1OC>>COc1ccc(C(N)=S)cc1OC,,CN(C)C=O,Cl,,,test
US03950359,CCCCCC(=O)CP(=O)(OC)OC.COC(=O)CCCCCCC1C(=O)CC(OC(C)=O)C1C=O>>CCCCCC(=O)C=CC1C(OC(C)=O)CC(=O)C1CCCCCCC(=O)OC,,C1CCOC1,,[H-].[Na+],,test
US04617316,BrBr.COc1cc([N+](=O)[O-])ccc1-c1cccs1>>COc1cc([N+](=O)[O-])ccc1-c1ccc(Br)s1,,C1COCCO1,CCOCC,O=S([O-])[O-].[Na+].[Na+],,test
US20060199960A1,COCCn1ccc(NC(=O)c2nc(C)ccc2N)n1.Fc1cc(F)cc(Br)c1>>COCCn1ccc(NC(=O)c2nc(C)ccc2Nc2cc(F)cc(F)c2)n1,[Pd],,,,,test
US20040048891A1,Nc1ccc(Oc2ccccc2)cc1.O=C(Cl)c1cc([N+](=O)[O-])ccc1Cl>>O=C(Nc1ccc(Oc2ccccc2)cc1)c1cc([N+](=O)[O-])ccc1Cl,,O,,C1CCOC1,CCN(CC)CC,test
US20130296371A1,CC(C)C(=O)O[C@H]1[C@H](C)OC(=O)[C@@H](NC(=O)OC(C)(C)C)COC(=O)[C@@H]1Cc1ccccc1>>CC(C)C(=O)O[C@H]1[C@H](C)OC(=O)[C@@H](NC(=O)OC(C)(C)C)COC(=O)[C@@H]1CC1CCCCC1,[Rh],C1CCOC1,,,,test
US05643932,CCCCCCCCCBr.CCOc1ccc(-c2nc(-c3ccc(OCOC)c(C(=O)O)c3)cs2)cc1OCC>>CCCCCCCCCOC(=O)c1cc(-c2csc(-c3ccc(OCC)c(OCC)c3)n2)ccc1OCOC,,CN(C)C=O,,[H-].[Na+],,test
US20090143352A1,CN(C)C(=O)c1cc(-c2cnc3c(c2)c(C2OCc4ccccc42)cn3COC(=O)C(C)(C)C)ccc1NC(=O)N1CCOCC1>>CN(C)C(=O)c1cc(-c2cnc3[nH]cc(C4OCc5ccccc54)c3c2)ccc1NC(=O)N1CCOCC1,,C1CCOC1,CO,[Na+].[OH-],,test
US20130072467A1,C#CC(C)NC1=NC(=O)S/C1=C\C1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1.Cl>>C#CC(C)NC1=NC(=O)S/C1=C\C1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1.Cl,,CCOC(C)=O,,,,test
US20110224204A1,Clc1ccc(OC2CCCCO2)c(-c2ccc(OCc3ccc4ccccc4n3)cc2)c1>>Oc1ccc(Cl)cc1-c1ccc(OCc2ccc3ccccc3n2)cc1,,CO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20070032515A1,Cc1nn(C(C)(C)C)c2nc(-c3ccc(OCc4ccccc4)c(Cl)c3)c3c(F)cc(O)c(F)c3c12>>Cc1n[nH]c2nc(-c3ccc(O)c(Cl)c3)c3c(F)cc(O)c(F)c3c12,,O=C(O)C(F)(F)F,,,,test
US20050256143A1,CNC(=O)[C@]1(n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)SC[C@@H]2OC(C)(C)O[C@@H]21>>CNC(=O)[C@]1(n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)SC[C@H](O)[C@@H]1O,,CC(=O)O,,,,test
US20160264598A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cc(F)ccc1O[Si](C)(C)C(C)(C)C>>COc1c(O[Si](C)(C)C(C)(C)C)ccc(F)c1C(=O)OC(C)(C)C,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US06107329,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.O=C1CNCCN1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCNC(=O)C1,,CN(C)C=O,ClCCl,[Na+].[OH-],,test
US20120077799A1,Nc1ncccc1-c1ccc(F)nc1.Oc1ccccc1>>Nc1ncccc1-c1ccc(Oc2ccccc2)nc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20030232873A1,COC(=O)Cc1ccc(Cl)c(NC(=O)Nc2ccccc2)c1>>O=C(O)Cc1ccc(Cl)c(NC(=O)Nc2ccccc2)c1,,CO,,[Na+].[OH-],,test
US20130065861A1,CCCCCCCCCCCCOC[C@H](CSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)OCCCCCCCCCCCC.CCOP(=O)(CCOCCOCCOCCN)OCC>>CCCCCCCCCCCCOC[C@H](CSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NCCOCCOCCOCCP(=O)(OCC)OCC)OCCCCCCCCCCCC,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060148858A1,CCC(CC)c1nn(-c2ccc(Cl)cn2)cc1CCCO.CCc1cccc(CC(=O)OC)c1O>>CCc1cccc(CC(=O)OC)c1OCCCc1cn(-c2ccc(Cl)cn2)nc1C(CC)CC,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20090099181A1,C[S@](=N)(=O)c1ccccc1.O=C(O)c1cncc(C#Cc2ccccc2)c1>>CS(=O)(=NC(=O)c1cncc(C#Cc2ccccc2)c1)c1ccccc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20070105904A1,Fc1ccc(CCl)nc1.O=Cc1ccc(O)cc1F>>O=Cc1ccc(OCc2ccc(F)cn2)cc1F,,O,,CN(C)C=O,[H-].[Na+],test
US20160229847A1,CCI.Cc1cn(-c2ccc3n(c2=O)CCN(Cc2c[nH]c4ccc(S(F)(F)(F)(F)F)cc24)C3=O)cn1>>CCn1cc(CN2CCn3c(ccc(-n4cnc(C)c4)c3=O)C2=O)c2cc(S(F)(F)(F)(F)F)ccc21,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US05512564,Cc1cccc(Br)c1.O=C1OC(=O)c2nccnc21>>Cc1cccc(C(=O)c2nccnc2C(=O)O)c1,,C1CCOC1,CCOCC,[Mg],[Cl-].[NH4+],test
US20120035155A1,CC(C)(C)OC(=O)N1CCc2cc(CO)ccc2C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCc2cc(COS(C)(=O)=O)ccc2C1,,CCOC(C)=O,,C1CCOC1,CCN(CC)CC,test
US20060173050A1,CC(C)O.N#Cc1c(N)cc(N)nc1Br>>CC(C)Oc1nc(N)cc(N)c1C#N,,O,,[Na],,test
US20070135477A1,Cn1c(-c2n[nH]cc2NC(=O)C(NC(=O)OC(C)(C)C)c2ccccc2)nc2cc(N3CCOCC3)ccc21>>Cn1c(-c2n[nH]cc2NC(=O)C(N)c2ccccc2)nc2cc(N3CCOCC3)ccc21,,C1COCCO1,Cl,CO,,test
US04971982,CC(C)=CC1(Cc2cncc[n+]2[O-])C=C(C#N)C=CC1O>>CC1(C)CC(c2cncc[n+]2[O-])c2cc(C#N)ccc2O1,,CCOCC,,,,test
US20040138283A1,c1ccc(COc2ccc3c(ccn3Cc3ccccc3)c2)cc1>>Oc1ccc2c(ccn2Cc2ccccc2)c1,[Pd],,,,,test
US20160214972A1,Cc1ncsc1-c1ccc(C#N)c(O)c1>>Cc1ncsc1-c1ccc(CN)c(O)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060281799A1,CCOC1=CCc2cccc(N)c2C1.S=C(Oc1ccccn1)Oc1ccccn1>>CCOC1=CCc2cccc(N=C=S)c2C1,,ClCCl,,,,test
US20120225062A1,CCOCCO.COC(=O)c1ccc(F)c(-c2c(F)cc(O)cc2F)n1>>CCOCCOc1cc(F)c(-c2nc(C(=O)OC)ccc2F)c(F)c1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160235716A1,COc1c([N+](=O)[O-])ccc2c1CCC21OC(=O)N(CC(=O)N(Cc2ccc(F)cc2)[C@@H](C)C2CC2)C1=O>>COc1c(N)ccc2c1CCC21OC(=O)N(CC(=O)N(Cc2ccc(F)cc2)[C@@H](C)C2CC2)C1=O,[Pd],C1CCOC1,,,,test
US20160031876A1,CC(C)(C)Sc1c(Br)cccc1/C=N/O>>Brc1cccc2cnsc12,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100144760A1,Cc1ccc(-c2ncccn2)c(C(=O)N2C[C@@H]3C[C@@H]3C[C@H]2CN)n1.FC(F)(F)c1cnc(Br)cn1>>Cc1ccc(-c2ncccn2)c(C(=O)N2C[C@@H]3C[C@@H]3C[C@H]2CNc2cnc(C(F)(F)F)cn2)n1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20020002190A1,CCOC(=O)Cc1csc(NC(=O)C(CC2CCCC2)c2ccc(Oc3ccccc3)cc2)n1>>O=C(Nc1nc(CCO)cs1)C(CC1CCCC1)c1ccc(Oc2ccccc2)cc1,,CCOCC,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110269737A1,COC(=O)c1cc(C(C)(C)C)cc(NC(=O)c2cc3cccc(CN4CCN(C(=O)C5CCCN5C)CC4)c3n2C)c1OC>>COc1c(NC(=O)c2cc3cccc(CN4CCN(C(=O)C5CCCN5C)CC4)c3n2C)cc(C(C)(C)C)cc1C(=O)O,,C1CCOC1,,[Na+].[OH-],,test
US20100041698A1,COc1cccc(OC)c1CN.O=C(O)c1ccccc1[N+](=O)[O-]>>COc1cccc(OC)c1CNC(=O)c1ccccc1[N+](=O)[O-],,ClCCl,,CC(C)COC(=O)Cl,CCN(CC)CC,test
US04052395,Cc1ccc(S(=O)(=O)Cl)cc1.O=C1CCC(c2cc(Cl)c(O)c(Cl)c2)=NN1>>Cc1ccc(S(=O)(=O)Oc2c(Cl)cc(C3=NNC(=O)CC3)cc2Cl)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20030008872A1,COc1ccc2c(C(=O)O)c(-c3cccc(F)c3)nn2n1.O=C1CCC(=O)N1Br>>COc1ccc2c(Br)c(-c3cccc(F)c3)nn2n1,,CCOC(C)=O,CN(C)C=O,,,test
US20140336388A1,Cn1nc(C2CCN(c3ccc(/N=C/c4ccc([N+](=O)[O-])o4)cc3F)CC2)oc1=O>>Cn1nc(C2CCN(c3ccc(NCc4ccc([N+](=O)[O-])o4)cc3F)CC2)oc1=O,CC(=O)O,CO,,[BH3-]C#N.[Na+],,test
US20110195991A1,Cc1cccc(O)c1C.NC(=O)CI>>Cc1cccc(OCC(N)=O)c1C,,CN(C)C=O,,[H-].[Na+],,test
US20020072516A1,CCOC(=O)C(=O)N(c1ccccc1C(=O)OC(c1ccccc1)c1ccccc1)c1ccc(C[C@H](NCCCCCO)C(=O)NC(=O)OC(C)(C)C)c2ccccc12.COC(=O)c1c(O)cc(C)cc1O>>COC(=O)c1c(O)cc(C)cc1OCCCCCNC(=O)[C@H](Cc1ccc(N(C(=O)C(=O)O)c2ccccc2C(=O)O)c2ccccc12)NC(C)=O,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140275224A1,CC(=O)c1ccccc1.O=C1Nc2ccccc2C1=O>>O=C(O)c1cc(-c2ccccc2)nc2ccccc12,,CCO,,[K+].[OH-],,test
US04036983,O=C(CCl)[c-]1cccc1.SC1CCCCC1.[Fe+2].c1cc[cH-]c1>>S=C(CC1CCCCC1)[c-]1cccc1.[Fe+2].c1cc[cH-]c1,,O,,C1COCCO1,[Na+].[OH-],test
US20130029971A1,CCOC(=O)CC1CCN(c2ncc(C(=O)NC3CC3)cc2N)CC1.O=C(Cl)c1cccc(Cl)c1>>CCOC(=O)CC1CCN(c2ncc(C(=O)NC3CC3)cc2NC(=O)c2cccc(Cl)c2)CC1,,CC#N,,,,test
US20110172187A1,CCOC(=O)Cl.Nc1cc([N+](=O)[O-])ccc1SCc1ccccc1>>CCOC(=O)Nc1cc([N+](=O)[O-])ccc1SCc1ccccc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20060004056A1,[O-][n+]1cccc(CC(c2ccc(OC(F)F)c(OC3CC3)c2)c2cnc(C(O)(C(F)(F)F)C(F)(F)F)s2)c1>>O=c1[nH]cccc1CC(c1ccc(OC(F)F)c(OC2CC2)c1)c1cnc(C(O)(C(F)(F)F)C(F)(F)F)s1,,CC(=O)OC(C)=O,,Cl,[Li+].[OH-],test
US20120129806A1,C=CCC1CCCC1=O.Cl[Se]c1ccccc1>>C=CCC1CCC([Se]c2ccccc2)C1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20050038056A1,COc1cccc(C=O)c1Cl.CSCS(C)=O>>COc1cccc(C=C(SC)S(C)=O)c1Cl,,C1CCOC1,,,,test
US20150218092A1,COc1cc(N2CCC(Oc3ccc(C4CC4)cc3)C2=O)ccc1OCOCC[Si](C)(C)C>>COc1cc(N2CCC(Oc3ccc(C4CC4)cc3)C2=O)ccc1O,,ClCCl,,Cl,,test
US05310737,[N-]=[N+]=NC1CCc2cc(F)ccc2NC1=O>>NC1CCc2cc(F)ccc2NC1=O,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080004302A1,CN.COC(=O)c1cc(C)cc(CO)c1>>CNC(=O)c1cc(C)cc(CO)c1,,C1CCOC1,,C[Al](C)C,,test
US20090257978A1,BrC(Br)(Br)Br.CC1(C)COCCN1CCO>>CC1(C)COCCN1CCBr,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20040048882A1,CON(C)C(=O)c1ccc(I)cc1.Clc1cccc(-c2onc3ccc(Br)cc23)c1>>O=C(c1ccc(I)cc1)c1ccc2noc(-c3cccc(Cl)c3)c2c1,,C1CCOC1,,O,[Li]CCCC,test
US20100267707A1,CC(C)(C)OC(=O)n1cc(B(O)O)c2cc(F)ccc21.Clc1ccnc(Cl)n1>>CC(C)(C)OC(=O)n1cc(-c2ccnc(Cl)n2)c2cc(F)ccc21,,C1COCCO1,,O=C([O-])O.[Na+],,test
US20140343151A1,CCCc1c(NC(=O)CC(C)(C)C(=O)O)cccc1OCCCOc1cc(O)c(-c2ccc(F)cc2)cc1CC.[Na+]>>CCCc1c(NC(=O)CC(C)(C)C(=O)[O-])cccc1OCCCOc1cc(O)c(-c2ccc(F)cc2)cc1CC.[Na+],,C1CCOC1,,O,,test
US20080076758A1,C1CNCCN1.O=S(=O)(Cl)C(F)(F)F>>O=S(=O)(N1CCNCC1)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20130210787A1,C=C(C)[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CCC(=O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>C=C(C)[C@@H]1CC[C@]2(N=C=O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CCC(=O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1COCCO1,,CCN(CC)CC,,test
US20080214495A1,COC(=O)[C@H]1CN(S(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)CC(=O)N1CC1CCN(c2ccc(=O)n(C)n2)CC1>>Cn1nc(N2CCC(CN3C(=O)CN(S(=O)(=O)c4cc5cc(Cl)ccc5[nH]4)C[C@@H]3C(=O)O)CC2)ccc1=O,,C1CCOC1,O,CC(=O)O,[Li+].[OH-],test
US07186730B2,C=Cc1cnc2ccccc2n1.COc1ccc2nccc(NC(=O)C3CCNCC3)c2n1>>COc1ccc2nccc(NC(=O)C3CCN(CCc4cnc5ccccc5n4)CC3)c2n1,,CCO,,CC(=O)O,[Na+].[OH-],test
US20110112127A1,COc1ccc(CN(C(=O)OC(C)(C)C)c2ccc(C=O)c(F)n2)cc1.Cc1cnc2c(c1)c(I)cn2[Si](C(C)C)(C(C)C)C(C)C>>COc1ccc(CN(C(=O)OC(C)(C)C)c2ccc(C(O)c3cn([Si](C(C)C)(C(C)C)C(C)C)c4ncc(C)cc34)c(F)n2)cc1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US04511734,CC1=CC(=O)CC(C)(C)C1.O=O.O=[O+][O-]>>CC(=O)CC(C)(C)CC(=O)O,,ClCCl,,O,,test
US03984465,C=O.CCC1Cc2cc(OCC(=O)O)c(Cl)c(Cl)c2C1=O>>CCC1(CO)Cc2cc(OCC(=O)O)c(Cl)c(Cl)c2C1=O,,O,,Cl,[Na+].[OH-],test
US20100152183A1,CC(c1ccccc1-c1ccc(Cl)cc1)N1CCN(c2ccc(C(=O)O)c(Oc3cccc4[nH]ccc34)c2)CC1.NS(=O)(=O)c1ccc(NCC2CCOCC2)c([N+](=O)[O-])c1>>CC(c1ccccc1-c1ccc(Cl)cc1)N1CCN(c2ccc(C(=O)NS(=O)(=O)c3ccc(NCC4CCOCC4)c([N+](=O)[O-])c3)c(Oc3cccc4[nH]ccc34)c2)CC1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20140194406A1,Cc1ccc(Cl)cc1-c1c(C(N)=O)cc(-c2ccnc(N)n2)n1COCC[Si](C)(C)C.O=C1CCC(=O)N1I>>Cc1ccc(Cl)cc1-c1c(C(N)=O)cc(-c2nc(N)ncc2I)n1COCC[Si](C)(C)C,,CCOC(C)=O,CN(C)C=O,,,test
US20120101147A1,C#Cc1ccc(NC(=O)OC(C)(C)C)c(N)c1.CC(=O)Nc1ccc(/C=C/C(=O)O)cc1>>C#Cc1ccc(N)c(NC(=O)/C=C/c2ccc(NC(C)=O)cc2)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100256097A1,CC1(C)CO1.Cc1nc(Cl)ccc1-c1c[nH]nn1>>Cc1nc(Cl)ccc1-c1cnnn1CC(C)(C)O,,CN(C)C=O,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US20140275071A1,CC(=O)Cn1c(=O)c2c(nc(Oc3cccc(OC(F)(F)F)c3)n2Cc2ccc(Cl)cc2)n(C)c1=O.CCC[Mg]Br>>CCCC(C)(O)Cn1c(=O)c2c(nc(Oc3cccc(OC(F)(F)F)c3)n2Cc2ccc(Cl)cc2)n(C)c1=O,,O,,C1CCOC1,,test
US05426119,COC(=O)CCCC=C(c1cccnc1)c1ccc2c(c1)CC(N)C2.O=S(=O)(Cl)c1ccc(Br)cc1>>COC(=O)CCCC=C(c1cccnc1)c1ccc2c(c1)CC(NS(=O)(=O)c1ccc(Br)cc1)C2,,ClC(Cl)Cl,,CCN(CC)CC,,test
US04372953,C1CCOC1.CCC1SCCCS1.Cn1nnnc1SCCCCl>>CCC(=O)CCCSc1nnnn1C,,CCCCCC,,[Li]CCCC,,test
US04447259,CC(Oc1ccc(O)cc1)C(=O)N1CCCO1.Clc1ccc(Br)c(Cl)c1>>CC(Oc1ccc(Oc2ccc(Cl)cc2Cl)cc1)C(=O)N1CCCO1,,O,c1ccccc1,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US04985427,CN=C=O.COC(=O)CN(N)c1cccc(Br)c1>>CN1C(=O)CN(c2cccc(Br)c2)NC1=O,,CC#N,,,,test
US20100305145A1,CCOC(=O)[C@H](C)C[C@@H](Cc1ccc(-c2cccc(Cl)c2)cc1)NC(=O)c1n[nH]c(=O)o1>>C[C@H](C[C@@H](Cc1ccc(-c2cccc(Cl)c2)cc1)NC(=O)c1n[nH]c(=O)o1)C(=O)O,,CO,,[Na+].[OH-],,test
US20140275179A1,CCOC(=O)c1c(-c2ccc(C(C)F)cc2)nsc1C(F)(F)F>>CC(F)c1ccc(-c2nsc(C(F)(F)F)c2CO)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04916233,C=O.Cc1c[nH]cn1.Cl.NCCSS(=O)(=O)O>>Cc1nc[nH]c1CSCCN.Cl,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20060079519A1,C#Cc1ccc(CN2CCOCC2)nc1.Cc1ccc(C(=O)O)cc1N=[N+]=[N-]>>Cc1ccc(C(=O)O)cc1-n1cc(-c2ccc(CN3CCOCC3)nc2)nn1,,CCO,,,,test
US04035499,O=C(CBr)c1ccccc1.c1ccc2cnccc2c1>>O=C(C[n+]1ccc2ccccc2c1)c1ccccc1.[Br-],,CCOCC,,,,test
US04863951,CC(O)Br.NC1CCc2cc3c(cc2C1)OCC3>>OCCNC1CCc2cc3c(cc2C1)OCC3,,O,,ClCCl,[Na+].[OH-],test
US20030207878A1,Clc1nnc(Cc2ccncc2)c2ccccc12.Oc1ccc2[nH]ccc2c1F>>Fc1c(Oc2nnc(Cc3ccncc3)c3ccccc23)ccc2[nH]ccc12,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020019404A1,N#CN.Nc1ccc(F)cc1.O=[N+]([O-])O>>N=C(N)Nc1ccc(F)cc1.O=[N+]([O-])O,,CCO,,,,test
US20070078121A1,CC(C)(C)c1cc(N)[nH]n1.Nc1ccc(-c2cccc3c2CNC3=O)cc1.O=C(Cl)OCC(Cl)(Cl)Cl>>CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)cc2)[nH]n1,,CCOC(C)=O,O,CCN(C(C)C)C(C)C,[Na+].[OH-],test
US20050182072A1,CC(Nc1cc(-c2cc3nccn3c(N3CC4CC3CN4)n2)ccn1)c1ccccc1.CCBr>>CCN1C[C@@H]2C[C@H]1CN2c1nc(-c2ccnc(N[C@@H](C)c3ccccc3)c2)cc2nccn12,,CC#N,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20150011546A1,CCc1cc(C)[nH]c(=O)c1CNC(=O)OC(C)(C)C.Cl>>CCc1cc(C)[nH]c(=O)c1CN.Cl,,C1COCCO1,,,,test
US05807864,CCN(CCC(=O)O)C(=S)Nc1c(C)cccc1C>>CCN1CCC(=O)N(c2c(C)cccc2C)C1=S,,CC(C)=O,,Cl,,test
US20160002175A1,CNc1cc(Cl)nc(N)n1.Cc1ccc(N)cc1B(O)O>>CNc1cc(-c2cc(N)ccc2C)nc(N)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20040214822A1,CN(C)C1(Cc2ccccc2)CCC(=O)CC1.Cn1ccc2ccccc21>>CN(C)C1(Cc2ccccc2)CCC(O)(c2cc3ccccc3n2C)CC1,,C1CCOC1,,CCCCC,[Li]C(C)(C)C,test
US05086049,Cc1oc(=O)oc1CBr.O=C(O)c1c2n(c3cc(N4CCNCC4)c(F)cc3c1=O)C(c1ccccc1)S2>>Cc1oc(=O)oc1CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)c2n3C(c3ccccc3)S2)CC1,,CN(C)C=O,,O=C([O-])O.[K+],,test
US20070244132A1,CS(=O)(=O)O.Cc1cc(Nc2ncnc3ccn(CCNC(=O)CS(C)(=O)=O)c23)ccc1Oc1cccc(C(F)(F)F)c1>>CS(=O)(=O)O.Cc1cc(Nc2ncnc3ccn(CCNC(=O)CS(C)(=O)=O)c23)ccc1Oc1cccc(C(F)(F)F)c1,,CCOC(C)=O,,,,test
US20100081692A1,COC(=O)Cc1ccc(F)c(F)c1O.C[C@@]1(COS(=O)(=O)c2cccc([N+](=O)[O-])c2)CO1>>COC(=O)Cc1ccc(F)c(F)c1OC[C@]1(C)CO1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05409886,CC(=O)C(C)NC(C)(C)c1cc(F)cc(Cl)c1.O=C(Cl)Cc1ccccc1F>>CC1=C(c2ccccc2F)C(=O)N(C(C)(C)c2cc(F)cc(Cl)c2)C1C,,c1ccncc1,,ClCCl,O=C([O-])O.[Na+],test
US20090069288A1,CCc1ccccc1N.O=C(Cl)c1cc(-c2ccccc2)c(C(F)(F)F)s1>>CCc1ccccc1-c1c(C(N)=O)sc(C(F)(F)F)c1-c1ccccc1,,CC#N,,c1ccncc1,,test
US20030064962A1,CC(C)(C)OC(=O)[C@@H]1CCC(=O)N1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)OC(=O)[C@@H]1CCC(=S)N1,,c1ccccc1,,,,test
US05866560,CC(=O)OCCCCC[C@@H]1Cc2cc(OC(C)=O)ccc2[C@H]2CC[C@@]3(C)[C@@H](C[C@@H](Br)C34OCCO4)[C@H]12>>C[C@]12CC[C@@H]3c4ccc(O)cc4C[C@@H](CCCCCO)[C@H]3[C@@H]1C=CC21OCCO1,,CO,CS(C)=O,[K+].[OH-],,test
US04956359,C/C=C/CN.FC(F)(F)c1ccc(OC2CNC2)cc1.O=C(n1ccnc1)n1ccnc1>>C/C=C/CNC(=O)N1CC(Oc2ccc(C(F)(F)F)cc2)C1,,CCN(CC)CC,,O=C(O)C(=O)O,,test
US05594023,CCN(CC)C(=O)Cl.Nc1ccccc1>>CCN(CC)C(=O)Nc1ccccc1,,c1ccncc1,,O,,test
US20080234255A1,CCOC(=O)C(C)(C)C#N>>COC(=O)C(C)(C)CN,[Ni],CO,,[H][H],,test
US20020032208A1,Cc1cc(F)c(N)cc1O.Cl.Clc1ncnc2cc(OCc3ccncc3)ccc12>>Cc1cc(F)c(Nc2ncnc3cc(OCc4ccncc4)ccc23)cc1O.Cl,,CC(C)O,,,,test
US20120329785A1,COc1ccc(Cn2nc3c(Cl)nc4ccccc4c3c2[N+](=O)[O-])cc1.COc1ccc(N)cc1OC>>COc1ccc(Nc2nc3ccccc3c3c([N+](=O)[O-])[nH]nc23)cc1OC,C1COCCO1,CO,,Cl,,test
US07732446B1,CCN(Cc1ccccc1)C(=O)Cc1cnc(CNC(=O)OC(C)(C)C)c2cc(OC)c(OC)cc12.Cl>>CCN(Cc1ccccc1)C(=O)Cc1cnc(CN)c2cc(OC)c(OC)cc12.Cl,,CCOC(C)=O,,,,test
US20030013713A1,CC(=O)OC(C)=O.COc1cc(C)[n+]([O-])nc1OC>>COc1cc(COC(C)=O)nnc1OC,,O,,,,test
US20110124618A1,O=C(O)c1cc(-c2cc(F)cc(C(F)(F)F)c2)n(-c2cccc(Cl)c2)n1.O=C1CN(C(=O)c2cc(-c3cccc(OCCO)c3)n(-c3cccc(Cl)c3)n2)CN1>>O=C1CN(C(=O)c2cc(-c3cc(F)cc(C(F)(F)F)c3)n(-c3cccc(Cl)c3)n2)CN1,,O=CO,,,,test
US20100075010A1,C=CCBr.N[C@@H](CS)C(=O)O>>C=CCSC[C@H](N)C(=O)O,,O,,CC(=O)O,[Na+].[OH-],test
US20130184262A1,N[C@@H]1CCCC[C@H]1NC1CCCN(Cc2ccccc2)C1.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)N[C@@H]1CCCC[C@H]1NC1CCCN(Cc2ccccc2)C1,,C1CCOC1,,CCN(CC)CC,,test
US05519034,Br.COc1ccc(Cl)c2c1C(C1(c3ccccc3)CCC1)N(C)CC2>>Br.CN1CCc2c(Cl)ccc(O)c2C1C1(c2ccccc2)CCC1,,CC(=O)O,,,,test
US20130274243A1,CC(=O)Nc1ccc(C(C)(C)C)cc1.O=[N+]([O-])O>>CC(=O)Nc1ccc(C(C)(C)C)cc1[N+](=O)[O-],,CC(=O)O,,CC(=O)OC(C)=O,,test
US20100197678A1,OCC(O)Cn1cc(C(O)(c2ccc3c(cnn3-c3ccc(F)cc3)c2)C(F)(F)F)c2ccc(Br)cc21>>O=CCn1cc(C(O)(c2ccc3c(cnn3-c3ccc(F)cc3)c2)C(F)(F)F)c2ccc(Br)cc21,,CC(C)=O,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20070244086A1,Cn1nccc1-c1cc(NC(=O)Nc2ccc(Cl)cc2)ccc1O.OCCN1CCCC1>>Cn1nccc1-c1cc(NC(=O)Nc2ccc(Cl)cc2)ccc1OCCN1CCCC1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150073019A1,COC(OC)N(C)C.O=c1cc(-c2cccc(C(F)(F)F)c2)[nH]n1-c1nc2ccccc2s1>>CN(C)C=C1C(=O)N(c2nc3ccccc3s2)N=C1c1cccc(C(F)(F)F)c1,,C1CCOC1,,CCOCC,,test
US04938790,COCOc1ccccc1C1(c2ccc(OC)c(OC)c2OCOC)CC1>>COc1ccc(C2(c3ccccc3O)CC2)c(O)c1OC,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05604229,CC(C)(C)OC(=O)NC(CO[Si](C)(C)C(C)(C)C)(CO[Si](C)(C)C(C)(C)C)CC(O)CO>>CC(C)(C)OC(=O)NC(CCC=O)(CO[Si](C)(C)C(C)(C)C)CO[Si](C)(C)C(C)(C)C,,C1COCCO1,O,,,test
US20020193382A1,CC(C)(C)OC(=O)Nc1ccc(CN2CCN(S(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC2=O)cc1.Cl>>Cl.Nc1ccc(CN2CCN(S(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC2=O)cc1,,CCOC(C)=O,CO,,,test
US20140011802A1,Fc1ccc([C@]23CO[C@H](COC(c4ccccc4)(c4ccccc4)c4ccccc4)[C@H]2CON3)c(F)c1Cl>>N[C@@]1(c2ccc(F)c(Cl)c2F)CO[C@H](COC(c2ccccc2)(c2ccccc2)c2ccccc2)[C@H]1CO,[Zn],CC(=O)O,,,,test
US05428037,Cc1ccc(-c2cccc(C)[n+]2[O-])cc1.O=P(Cl)(Cl)Cl>>Cc1ccc(-c2cccc(CCl)n2)cc1,,CCN(CC)CC,ClC(Cl)Cl,,,test
US09156827B2,COC(=O)COc1c(C)cc(OC)cc1C(=O)OC>>COc1cc(C)c(OCC(=O)O)c(C(=O)O)c1,,O,,CO,[Na+].[OH-],test
US06136823,CCOC=C(C(=O)OCC)C(=O)c1cc(F)c([N+](=O)[O-])c(C)c1F.COc1cc(N)c(F)cc1F>>CCOC(=O)c1cn(-c2cc(OC)c(F)cc2F)c2c(C)c([N+](=O)[O-])c(F)cc2c1=O,,ClC(Cl)Cl,,Br,CCN(CC)CC,test
US20120238539A1,O=C(Cl)C(=O)Cl.O=C(O)c1ccc(N2CCCC2=O)cc1>>O=C(Cl)c1ccc(N2CCCC2=O)cc1,CN(C)C=O,ClCCl,,,,test
US05530119,O=C(N1CCNCC1)N1CCOCC1>>O=C(N1CCNCC1)N1CCOCC1,,CC#N,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20060025433A1,BrC(Br)(Br)Br.OCCc1cccnc1>>BrCCc1cccnc1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20080146566A1,COC(=O)c1ccc(C)c(-n2ccc3ccc(C#CCN4CCOCC4)cc3c2=O)c1>>COC(=O)c1ccc(C)c(-n2ccc3ccc(CCCN(C)C)cc3c2=O)c1,[Pd],CCO,,CCOC(C)=O,CO,test
US20150080365A1,CCO.Cc1cc([N+](=O)[O-])cc(Br)[n+]1[O-]>>CCOc1cc(C)[n+]([O-])c(Br)c1,,CCO,,C,C[O-].[Na+],test
US20080312192A1,CN1CCN(Cc2ccc(N)cc2C(F)(F)F)CC1.COc1cccc(Nc2nccc(Oc3ccc(N)c(C)c3)n2)c1.Cc1cc(Oc2ccnc(NCCCCN(C)C)n2)ccc1NC(=O)Nc1ccc(-c2cccc(Cl)c2)c(C(F)(F)F)c1>>COc1cccc(Nc2nccc(Oc3ccc(NC(=O)Nc4ccc(CN5CCN(C)CC5)c(C(F)(F)F)c4)cc3)n2)c1,,CO,ClCCl,,,test
US20110293519A1,CI.CN(C)c1ccc(N(C)C)cc1>>CN(C)c1ccc([N+](C)(C)C)cc1.[I-],,CC(Cl)Cl,,ClCCl,,test
US20090253699A1,COC(=O)c1cccc(C(=O)CCC(=O)c2ccc(C(C)C)cc2)c1>>COC(=O)c1cccc(-c2ccc(-c3ccc(C(C)C)cc3)o2)c1,,CCOC(C)=O,Cc1ccccc1,Cc1ccc(S(=O)(=O)O)cc1,,test
US20160272595A1,CCS(=O)(=O)c1ccc(Cl)cc1Cn1cnc2cc(CO)c(C(F)(F)F)cc2c1=O.CS(=O)(=O)Cl>>CCS(=O)(=O)c1ccc(Cl)cc1Cn1cnc2cc(COS(C)(=O)=O)c(C(F)(F)F)cc2c1=O,,ClCCl,,CCN(CC)CC,O,test
US20110294850A1,CCCN(CCC)C(=O)CC1CN(C)c2ccc(OC)cc21>>CCCN(CCC)C(=O)CC1CN(C)c2ccc(O)cc21,,CCOCC,ClCCl,BrB(Br)Br,CO,test
US20160122335A1,COC(=O)c1cccc(-c2nc(CO)cs2)n1.C[Si](C)(C)CCOCCl>>COC(=O)c1cccc(-c2nc(COCOCC[Si](C)(C)C)cs2)n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05665856,COc1ccc(-c2ccc(O)cc2)cc1.OCCCCCCBr>>COc1ccc(-c2ccc(OCCCCCCO)cc2)cc1,,CCO,,[Na+].[OH-],,test
US20110118250A1,CCCC[Sn](CCCC)(CCCC)c1ccccn1.COC(=O)c1cnc(OC2CCCC2)c(Br)c1>>COC(=O)c1cnc(OC2CCCC2)c(-c2ccccn2)c1,,CN(C)C=O,,,,test
US20090156594A1,CO.O=C(O)Cc1ccc2ncccc2c1>>COC(=O)Cc1ccc2ncccc2c1,,ClCCl,,O=S(=O)(O)O,,test
US20120178715A1,CO.Cc1ccc(S(=O)(=O)OCC2(C)COC(=O)N2)cc1>>COCC1(C)COC(=O)N1,,CO,O,C[O-].[Na+],,test
US20040167224A1,C=Cc1cncc(OC(C)(C)C)n1.c1ccc(OCC2CCNCC2)cc1>>CC(C)(C)Oc1cncc(CCN2CCC(COc3ccccc3)CC2)n1,,CCO,,,,test
US20120028964A1,C[C@H](OC[C@H](N)CO)c1ccc(F)cc1.N#CBr>>C[C@H](OC[C@H]1COC(N)=N1)c1ccc(F)cc1,,C1CCOC1,,O,O=C([O-])[O-].[K+].[K+],test
US20080076745A1,CC(C)(C)OC(=O)NCCC[C@H](NC(=O)OCc1ccccc1)C(=O)O.CC(C)(C)OC(=O)NCCN>>CC(C)(C)OC(=O)NCCC[C@H](NC(=O)OCc1ccccc1)C(=O)NCCNC(=O)OC(C)(C)C,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20100087429A1,COc1ccc(Oc2ccc(Br)cc2)c(C(=O)O)c1>>COc1ccc2oc3ccc(Br)cc3c(=O)c2c1,,O,,O=S(=O)(O)O,,test
US08163923B2,CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(NC(=O)OCc6ccccc6)CC5)c(OC)cc34)ccc12>>CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12,[Pd],CCO,,,,test
US04211867,N.S=C=NC1c2ccccc2-c2ccccc21>>NC(=S)NC1c2ccccc2-c2ccccc21,,CCOCC,,,,test
US20130131016A1,Br.Nc1cc(F)c(F)c(Cl)c1>>Fc1cc(Br)cc(Cl)c1F,[Cu]Br,O,,O=N[O-].[Na+],,test
US20110053916A1,CC(C)(C)NS(=O)(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)s1.CC(C)(C)c1cc(Nc2nc(Br)ncc2Cl)n[nH]1>>CC(C)(C)NS(=O)(=O)c1ccc(-c2ncc(Cl)c(Nc3cc(C(C)(C)C)[nH]n3)n2)s1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20140249126A1,CC(C)(C)N.CCOC(=O)C(=CN(C)C)C(=O)c1cc(F)c(F)cc1F>>CCOC(=O)c1cn(C(C)(C)C)c2cc(F)c(F)cc2c1=O,,CCOCC,O,CCO,O=C([O-])[O-].[K+].[K+],test
US05925635,N#Cc1cccc(N=C=O)c1.Nc1ccc(Br)cc1>>N#Cc1cccc(NC(=O)Nc2ccc(Br)cc2)c1,,ClC(Cl)Cl,,C1CCOC1,,test
US20140018533A1,Cc1cc(O)ccc1[N+](=O)[O-].ClCc1ncccn1>>Cc1cc(OCc2ncccn2)ccc1[N+](=O)[O-],,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20070244092A1,CC(C)(C)c1nc2cc(S(=O)(=O)Cl)ccc2n1CC1CCC(F)(F)CC1.OC1CNC1>>CC(C)(C)c1nc2cc(S(=O)(=O)N3CC(O)C3)ccc2n1CC1CCC(F)(F)CC1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,Cl,test
US07928107B2,Cc1ccc2c(N3CCC[C@@H](CNC(=O)OC(C)(C)C)C3)nc(-c3ccccc3O)nc2c1>>Cc1ccc2c(N3CCC[C@@H](CN)C3)nc(-c3ccccc3O)nc2c1,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20040157849A1,CC(C)(C)c1ccc(CN)cc1.Cn1ncc2c(N)cccc21.O=C(Cl)Cl>>Cn1ncc2c(NC(=O)NCc3ccc(C(C)(C)C)cc3)cccc21,,Cc1ccccc1,,CC(C)NC(C)C,,test
US20120027780A1,CNc1ccc(C(=O)N(CCC(=O)OC)c2ccccc2)cc1N.N#Cc1ccc(NCC(=O)O)cc1>>CNc1ccc(C(=O)N(CCC(=O)OC)c2ccccc2)cc1NC(=O)CNc1ccc(C#N)cc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20130190248A1,CC(C)(C)OC(=O)N[C@@H](CN)C(=O)O.NCCN1CCN(C(=O)OCc2ccccc2)CC1.O=C(O)C(F)(F)F>>NCCN1CCN(C(=O)OCc2ccccc2)CC1.NC[C@H](N)C(=O)O.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20030181519A1,COc1ccc(-c2ccc3c(Br)c(OC)ccc3c2)cc1.O=S(=O)(c1ccccc1)N(F)S(=O)(=O)c1ccccc1>>COc1ccc(-c2ccc3c(F)c(OC)ccc3c2)cc1,,C1CCOC1,O,[Li]CCCC,,test
US05223510,CCc1sc2ccc([N+](=O)[O-])cc2c1C(=O)c1ccc(OC)cc1>>CCc1sc2ccc([N+](=O)[O-])cc2c1C(=O)c1ccc(O)cc1,,O,,Cl,c1ccncc1,test
US20090048247A1,C=C(CC(=O)OC)C(=O)OC.ON=Cc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1>>COC(=O)CC1(C(=O)OC)CC(c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)=NO1,,C1CCOC1,,[Na+].[O-]Cl,,test
US06333337B1,O=[N+]([O-])c1ccc2c(c1)CC(O)CC2>>O=[N+]([O-])c1ccc2c(c1)C=CCC2,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04304790,CC(=O)CCN(C)c1ccccc1.NO>>CC(CCN(C)c1ccccc1)=NO,,CCO,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20060030613A1,CC(C)(C)c1ccc(CNCCc2cccc(C(F)(F)F)c2)cc1.O=C(O)c1ccc(F)c2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCc2cccc(C(F)(F)F)c2)C(=O)c2ccc(F)c3cc[nH]c23)cc1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20040192742A1,CC(C)(C=O)NC(=O)OC(C)(C)C.c1ccc(C2SCCCS2)cc1>>CC(C)(C)OC(=O)NC(C)(C)C(O)C1(c2ccccc2)SCCCS1,,C1CCOC1,,CC(=O)O,[Li]CCCC,test
US20040102439A1,CCOC(=O)[C@H](Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)NCc1ccc(F)cc1.CS(=O)(=O)O>>CCOC(=O)[C@H](Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)NCc1ccc(F)cc1.CS(=O)(=O)O,,CCO,,CC(C)OC(C)C,,test
US20040242573A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCCOc1ccccc1Br>>Cc1ccc(S(=O)(=O)OCCOc2ccccc2Br)cc1,,ClCCl,,CCN(CC)CC,O,test
US04288436,CCON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3CC(=O)O)CS[C@H]12)c1csc(NC=O)n1>>CCON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3CC(=O)O)CS[C@H]12)c1csc(N)n1,,CO,,Cl,,test
US20030220495A1,O=C([O-])c1ccc(C=C(Cn2ccnc2)c2nccs2)cc1>>O=C(O)c1ccccc1,,CO,,[Na+].[OH-],,test
US05665856,N#Cc1ccc(-c2ccc(O)cc2)cc1.OCCCCl>>N#Cc1ccc(-c2ccc(OCCCO)cc2)cc1,,CCO,,[Na+].[OH-],,test
US20090023703A1,CC(=O)Cl.CC(C)(C)OC(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)[C@@H](N)Cc1ccc(F)cc1.Cl,,CCOC(C)=O,,CO,,test
US20040063780A1,CSCc1ccc(CN=[N+]=[N-])o1>>CSCc1ccc(CN)o1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04923857,C=CCOC(=O)N1C[C@H](OC(=O)N(C)C)C[C@H]1C=C(C)C(=O)C[C@H]1NC(=O)[C@@H]1[C@@H](C)O[Si](C)(C)C(C)(C)C.CCOC(C)=O.ClCCl.O>>C=CCOC(=O)C(=O)N1C(=O)[C@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)[C@H]1CC(=O)C(C)=C[C@@H]1C[C@@H](OC(=O)N(C)C)CN1C(=O)OCC=C,,ClCCl,,CCN(CC)CC,,test
US20030055076A1,COC(=O)[C@H](Cc1ccc(OCCN2c3ccccc3Sc3ccc(Cl)cc32)cc1)Nc1ccccc1C(=O)c1ccccc1>>O=C(c1ccccc1)c1ccccc1N[C@@H](Cc1ccc(OCCN2c3ccccc3Sc3ccc(Cl)cc32)cc1)C(=O)O,,CCO,,[Na+].[OH-],,test
US05210092,Cc1ccc(-n2cc(Cl)c(Cl)c2C#N)cc1.O=C1CCC(=O)N1Br>>N#Cc1c(Cl)c(Cl)cn1-c1ccc(CBr)cc1,CC(C)(C#N)N=NC(C)(C)C#N,ClC(Cl)(Cl)Cl,,,,test
US20150232481A1,C=CCc1cc(C)ccc1C(=O)OC>>C=CCc1cc(C)ccc1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070299051A1,COC(=O)c1cc(C)c2c(c1)S(=O)(=O)Cc1cc(N(CCCl)CCCl)cc(Cl)c1O2>>Cc1cc(C(=O)O)cc2c1Oc1c(Cl)cc(N(CCCl)CCCl)cc1CS2(=O)=O,,C1CCOC1,,[Na+].[OH-],,test
US04034090,CC1=C(C(=O)OCC(Cl)(Cl)Cl)N2C(=O)C(N)C2SC1.O=C(Cl)Cc1csc(=O)s1>>CC1=C(C(=O)O)N2C(=O)C(NC(=O)Cc3csc(=O)s3)C2SC1,,CCOC(C)=O,ClC(Cl)Cl,CCN(CC)CC,,test
US20150376208A1,C=CC(=O)Cl.Nc1cc(Br)ccc1Cl>>C=CC(=O)Nc1cc(Br)ccc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090163472A1,CC(C)(C)OC(=O)N1C[C@@H](Br)[C@H](O)C1.NCc1ccccc1>>CC(C)(C)OC(=O)N1C[C@@H](NCc2ccccc2)[C@H](O)C1,,[Na+],[OH-],,,test
US20030153752A1,COc1cc(-c2cn(C3CCOCC3)c3ncnc(N)c23)ccc1NC(=O)OCc1cccnc1.Cl>>COc1cc(-c2cn(C3CCOCC3)c3ncnc(N)c23)ccc1NC(=O)OCc1cccnc1.Cl,,CCOC(C)=O,CCOCC,,,test
US20160024044A1,CCOC(=O)NCC(c1ccc(Cl)c(Cl)c1)C(O)c1ccccc1>>CNCC(c1ccc(Cl)c(Cl)c1)C(O)c1ccccc1,,C1CCOC1,,,,test
US20120259123A1,CC(C)(C)OC(=O)CN(C(=O)OC(C)(C)C)c1cccc(C(Cc2ccc(C3(Cc4ccccc4)CC3)cc2)NS(=O)(=O)c2ccccn2)n1>>O=C(O)CNc1cccc(C(Cc2ccc(C3(Cc4ccccc4)CC3)cc2)NS(=O)(=O)c2ccccn2)n1,,O,,C1CCOC1,Cl,test
US20100004245A1,CCC(C)c1ccccc1OC1CCNCC1.CCOC(=O)c1cncc(-c2cnc(Br)nn2)c1>>CCOC(=O)c1cncc(-c2cnc(N3CCC(Oc4ccccc4C(C)CC)CC3)nn2)c1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US05041455,C=CCOc1nsnc1-c1cccnc1.CI>>C=CCOc1nsnc1-c1ccc[n+](C)c1.[I-],,CC(C)=O,,,,test
US20090118275A1,CCOC(=O)c1nc(-c2ccccc2)sc1N.O=C=NS(=O)(=O)Cl>>CCOC(=O)c1nc(-c2ccccc2)sc1NC(N)=O,,ClCCl,,O=C([O-])O.[Na+],,test
US04254133,Cc1cccc(N)c1C.Cl.ClCC1=NCCN1>>Cc1cccc(NCC2=NCCN2)c1C.Cl,,CCO,,,,test
US20100216795A1,C#CCOc1ccc(N)cc1.S=C(Cl)Cl>>C#CCOc1ccc(N=C=S)cc1,,ClCCl,,CCN(CC)CC,,test
US20110112134A1,CCOC(=O)Cc1c2n(c3cccnc13)CC(N(C)S(=O)(=O)c1ccc(F)cc1)CC2>>CN(C1CCc2c(CC(=O)O)c3ncccc3n2C1)S(=O)(=O)c1ccc(F)cc1,,CO,O,C1CCOC1,[Na+].[OH-],test
US20050043544A1,CCOC(=O)C[Zn]Br.CCOC(C)=O.N#Cc1ccccc1F>>CCOC(=O)CC(=O)c1ccccc1F,,C1CCOC1,,Cl,,test
US20050069522A1,Fc1cccc(N=C=S)c1.NCc1ccco1>>Fc1cccc(NC(=S)NCc2ccco2)c1,,ClCCl,,,,test
US06025352,O=C(O)c1ccncc1S>>OCc1ccncc1S,,C1CCOC1,,B,,test
US05607956,Brc1ccsc1.CC(=O)c1ocnc1C>>Cc1ncoc1C(C)(O)c1ccsc1,,CCOCC,,O,[Li]CCCC,test
US20040176308A1,CC(C)c1cc(OCc2ccccc2)nn1CCO.O=C(Cl)c1ccccc1>>CC(C)c1cc(OCc2ccccc2)nn1CCOC(=O)c1ccccc1,,ClCCl,,CCN(CC)CC,O,test
US20090005346A1,CC(C)P(=O)(CO[C@H](COCc1ccccc1)COC(c1ccccc1)(c1ccccc1)c1ccccc1)C(C)C>>CC(C)P(=O)(CO[C@H](CO)COCc1ccccc1)C(C)C,,CCOC(C)=O,,C1COCCO1,Cl,test
US20070173522A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Clc1ccc(Sc2ccccc2Br)cc1>>CC(C)(C)OC(=O)N1CCC(O)(c2ccccc2Sc2ccc(Cl)cc2)CC1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20060052422A1,CSc1nsc(C2CCCC2)n1.O=C(OO)c1cccc(Cl)c1>>CS(=O)(=O)c1nsc(C2CCCC2)n1,,ClC(Cl)Cl,,O=S([O-])O.[Na+],,test
US20040006067A1,BrCC1CC1.CC(C)(C)OC(=O)N1CCC(c2ccccc2NS(C)(=O)=O)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccccc2N(CC2CC2)S(C)(=O)=O)CC1,,CN(C)C=O,,[H-].[Na+],,test
US06599721B2,CCC(O)(C#N)C(F)(F)F.O=S(=O)(O)O>>CCC(O)(C(N)=O)C(F)(F)F,,CCOCC,,O,,test
US20130217660A1,CCNCC.O=C(CCl)N[C@@H]1CC[C@@H](C(=O)NC(c2ccc(F)cc2)c2ccc(F)cc2)[C@H](c2ccc(Br)cc2)C1.O=C(O)C(F)(F)F>>CC[NH+](CC)CC(=O)N[C@@H]1CC[C@@H](C(=O)NC(c2ccc(F)cc2)c2ccc(F)cc2)[C@H](c2ccc(Br)cc2)C1.O=C([O-])C(F)(F)F,,CN(C)C=O,,,,test
US20130102776A1,COc1c(F)cc2c(c1CCC1CCN(C(=O)OC(C)(C)C)CC1)OCC2=O.O=Cc1n[nH]c2ccccc12>>COc1c(F)cc2c(c1CCC1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccccc13)C2=O,,CO,,C1CCNCC1,,test
US20130303533A1,CCOC(=O)C#N.Cn1cc(C(N)=O)c(N)n1>>CCOC(=O)c1nc(O)c2cn(C)nc2n1,,CC(=O)O,,CO,Cl,test
US20050239751A1,CCCN=C=O.Cc1cc(C=O)cc(C)c1O>>CCCNC(=O)Oc1c(C)cc(C=O)cc1C,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20100010035A1,CCOC(=O)c1ccc(Br)c(CBr)c1.CO>>CCOC(=O)c1ccc(Br)c(COC)c1,,CN(C)C=O,,Cl,C[O-].[Na+],test
US20140371199A1,COC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1NC(C)=O.N#Cc1ccc(-c2cnc3ccc(Br)cn23)cc1>>COC(=O)c1ccc(-c2ccc3ncc(-c4ccc(C#N)cc4)n3c2)cc1NC(C)=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20150087631A1,CC(C)(C)CNCC(O)c1ccccc1.Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1>>CC(C)(C)CNCC(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccccc1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20110212918A1,COc1cc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)ccc1F>>O=S(=O)(Nc1ccc2c(c1)B(O)OC2)c1ccc(F)c(O)c1,,ClCCl,,BrB(Br)Br,,test
US20140005213A1,CC(C)(C)OC(=O)N1C[C@@H](N=[N+]=[N-])[C@H](O)C1.CI>>CO[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1N=[N+]=[N-],,CCOCC,CN(C)C=O,O,[H-].[Na+],test
US20110059954A1,Cc1cccc2c1OCC2O>>Cc1cccc2c1OCC2,[Pd],CC(=O)O,,CC(=O)OC(C)=O,,test
US20090247746A1,CC(O)c1sccc1S(=O)(=O)N(C)c1cccc2cc(-c3nccs3)[nH]c12>>CC(=O)c1sccc1S(=O)(=O)N(C)c1cccc2cc(-c3nccs3)[nH]c12,,CC#N,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US20140058103A1,CI.COc1nc2c(Cl)ncnc2[nH]c1=O>>COc1nc2c(Cl)ncnc2n(C)c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06204264B1,NCCCN1CCOCC1.O=[N+]([O-])c1ccccc1Cl>>O=[N+]([O-])c1ccccc1NCCCN1CCOCC1,,c1ccncc1,,Cc1ccccc1,,test
US20070078125A1,COc1cc(-n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)ccc1N1CC[C@@H](O)C1.O=C(Cl)c1ccccc1>>COc1cc(-n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)ccc1N1CC[C@@H](OC(=O)c2ccccc2)C1,,O,c1ccncc1,,,test
US20160130262A1,COc1ccc(-c2cc(-c3ccccc3Cl)no2)cc1.O=C1CCC(=O)N1Br>>COc1ccc(-c2onc(-c3ccccc3Cl)c2Br)cc1,Cc1ccc(S(=O)(=O)O)cc1,ClCCl,,,,test
US20150353533A1,CCOC(=O)c1cc(C)n(Cc2ccc(C)cc2)n1>>Cc1ccc(Cn2nc(C(=O)O)cc2C)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20090209755A1,CO[C@@H]1C[C@@H](CO)[C@](NC(=S)NC(=O)OCC2c3ccccc3-c3ccccc32)(c2ccccc2F)C1>>CO[C@H]1C[C@H]2CSC(N)=N[C@@]2(c2ccccc2F)C1,,CO,,,,test
US20040092737A1,CI.NC(=S)NCc1ccc2c(c1)Nc1nccnc1S2>>CSC(=N)NCc1ccc2c(c1)Nc1nccnc1S2,,CC(C)=O,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130245049A1,O=Cc1ccccc1[N+](=O)[O-]>>Nc1ccccc1C=O,[Fe],O,,CCO,Cl,test
US20100267712A1,C=O.Cn1ccc2cc(N3Cc4ccc(N)cc4C3=O)ccc21.[BH3-]C#N>>CN(C)c1ccc2c(c1)C(=O)N(c1ccc3c(c1)CCN3C)C2,,CC(=O)O,CCOC(C)=O,[Na+].[OH-],,test
US20040204431A1,NC(=O)c1cc(Br)ccc1N.O=C(Cl)c1ccccc1F>>NC(=O)c1cc(Br)cc(N)c1C(=O)c1ccccc1F,,ClC(Cl)Cl,,Cl,c1ccncc1,test
US20160222028A1,O=Cc1ncc(Cl)nc1Cl.OCCNCc1ccccc1>>OCCN(Cc1ccccc1)Cc1ncc(Cl)nc1Cl,,C1CCOC1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20150291595A1,CC1(C)OB(c2cc(O)cc(C(F)F)c2)OC1(C)C.Cc1ccn2nc(CNc3ncnc(N)c3Br)n(-c3ccccc3)c(=O)c12>>Cc1ccn2nc(CNc3ncnc(N)c3-c3cc(O)cc(C(F)F)c3)n(-c3ccccc3)c(=O)c12,,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140206688A1,CC(C)(C)S(=O)(=O)c1cc2c(Nc3ccc4scnc4c3)ncnc2cc1O.CCI>>CCOc1cc2ncnc(Nc3ccc4scnc4c3)c2cc1S(=O)(=O)C(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140364412A1,CC(C)(C)c1cc(NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCCCC5)n4c3)c3ccccc32)n(-c2ccc(Cl)c(OCCOC3CCCCO3)c2)n1>>CC(C)(C)c1cc(NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCCCC5)n4c3)c3ccccc32)n(-c2ccc(Cl)c(OCCO)c2)n1,,CO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20090312322A1,CNC(=O)c1cc2c(cc1Br)NC(=O)C2.Clc1ncnc2cc(OCCCN3CCOCC3)ccc12>>CNC(=O)c1cc2c(cc1Br)NC(=O)C2c1ncnc2cc(OCCCN3CCOCC3)ccc12,,CN(C)C=O,,[H-].[Na+],,test
US06184225B2,COCCNCCOc1cc2nc[nH]c(=O)c2cc1OC.O=S(Cl)Cl>>COCCNCCOc1cc2ncnc(Cl)c2cc1OC,,CN(C)C=O,,,,test
US20080039459A1,CC(=O)Cl.CC(C)(N)c1cc2nc(Cl)nc(N3CCOCC3)c2s1.CC1(C)OB(c2cccc3[nH]ncc23)OC1(C)C>>CC(=O)NC(C)(C)c1cc2nc(-c3cccc4[nH]ncc34)nc(N3CCOCC3)c2s1,,ClCCl,,CCN(CC)CC,,test
US20120190675A1,C[C@H](NCCC1(O)CCC2(CC1)OCC(C)(C)CO2)c1ccc(Br)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>C[C@@H](c1ccc(Br)cc1)N1CCC2(CCC(=O)CC2)OC1=O,,CC(C)=O,ClCCl,CCN(C(C)C)C(C)C,Cl,test
US20100152210A1,Cc1cc(C)n(-c2nc(N(C(=O)OC(C)(C)C)c3ccc(F)cc3)c3ncn(Cc4ccccc4)c3n2)n1>>Cc1cc(C)n(-c2nc(Nc3ccc(F)cc3)c3ncn(Cc4ccccc4)c3n2)n1,,Cl,,,,test
US20030009034A1,CCN(CC)CC.COc1ccc([C@H]2CCN[C@@H]2c2ccccn2)cc1.Nc1cc(Cl)ccc1O.S=C=S>>COc1ccc([C@H]2CCN(C(=S)Nc3nc4cc(Cl)ccc4o3)[C@@H]2c2ccccn2)cc1,,C1CCOC1,,OO,,test
US05292747,CCOC(=O)C1CCc2cc3ccccc3n2C1.CCOC(=O)CBr>>CCOC(=O)CC1(C(=O)OCC)CCc2cc3ccccc3n2C1,,C1CCOC1,CCCCCC,CC(C)NC(C)C,[Li]CCCC,test
US20100113424A1,CN(C(=O)OC(C)(C)C)C1CN(Cc2ccccc2)CC1c1ccccc1>>CN(C(=O)OC(C)(C)C)C1CNCC1c1ccccc1,[Pd],CO,,O=C[O-].[NH4+],,test
US20150320702A1,CCC(=O)Cl.NC1=CC(=O)c2ccccc2C1=O>>CCC(=O)NC1=CC(=O)c2ccccc2C1=O,,C1CCOC1,,[H-].[Na+],,test
US20110245458A1,CCOC(=O)Cn1cnc2c(NC(=O)c3ccccc3)ncnc21>>O=C(O)Cn1cnc2c(NC(=O)c3ccccc3)ncnc21,,O,,Cl,[Na+].[OH-],test
US20020012639A1,CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1.NCCCBr>>CC(=O)Nc1ccc(S(=O)(=O)NCCCBr)cc1,,CC(C)=O,O,Br,O=C([O-])O.[Na+],test
US20120077847A1,COC(=O)C(O)CCCC/C=C/c1ccc(F)nc1>>COC(=O)C(O)CCCCCCc1ccc(F)nc1,[Pd],CCO,,,,test
US20030166639A1,Cc1cc(NC(=O)CC(=O)c2cccc(-c3ccncc3)c2)c(NC(=O)OC(C)(C)C)cc1Cl>>Cc1cc2c(cc1Cl)N=C(c1cccc(-c3ccncc3)c1)CC(=O)N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160009720A1,CC(C)(C)OC(=O)N1CC[C@@H](COc2nc(-c3ccc(C#N)cc3)c(Cl)nc2N)C1.O=CCCl>>N#Cc1ccc(-c2nc(OC[C@@H]3CCNC3)c3nccn3c2Cl)cc1,,CCO,,,,test
US04377580,COC=C(C(=O)OC)C(=O)OC.Nc1ncnc2ccc(NC(=O)CCC3CCCC3)cc12>>COC(=O)c1cnc2c3cc(NC(=O)CCC4CCCC4)ccc3ncn2c1=O,,CN(C)C=O,,O,,test
US20080153799A1,CCOc1cc2ncc(C(N)=O)c(Nc3cccc(CCl)c3CC)c2cc1OCC.c1c[nH]cn1>>CCOc1cc2ncc(C(N)=O)c(Nc3cccc(Cn4ccnc4)c3CC)c2cc1OCC,,CN1CCCC1=O,O,,,test
US20110269783A1,C1CCNC1.COC(=O)c1ccc(F)cc1N=C=S>>COC(=O)c1ccc(F)cc1NC(=S)N1CCCC1,,C1CCOC1,,O,,test
US05374454,[K].c1ccc2c(c1)cnc1ccccc12>>[K].c1ccc2c(c1)cnc1ccccc12,,COCCOC,,,,test
US04078142,COC(=O)c1cc([N+](=O)[O-])c(C(C)(C)C)cc1C(=O)OC>>COC(=O)c1cc(N)c(C(C)(C)C)cc1C(=O)OC,[Pd],CO,,[H][H],,test
US20070298104A1,CCOC(=O)c1ncc2cc(OCc3ccccc3)ccc2c1O.O=C1CCC(=O)N1Br>>CCOC(=O)c1nc(Br)c2cc(OCc3ccccc3)ccc2c1O,,CC#N,,,,test
US04289524,CC1CC(C)(C)Cc2nc(N)sc21.CN=C=O>>CNC(=O)Nc1nc2c(s1)C(C)CC(C)(C)C2,,CCOC(C)=O,,,,test
US20100035865A1,CC(C)S(=O)(=O)N[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@H]1c1ccc(-c2ccccc2)cc1>>CC(C)S(=O)(=O)N[C@@H]1CNCC[C@H]1c1ccc(-c2ccccc2)cc1,,C1COCCO1,CO,Cl,,test
US20040198784A1,COc1csc(S(N)(=O)=O)c1.O=C1CCC(=O)N1Br>>COc1cc(S(N)(=O)=O)sc1Br,,ClCCl,,,,test
US20090298807A1,Cc1sc(C(C)C)nc1C(=O)O.OCCc1cccc(CN2CCC3(CC2)CNCCO3)c1F>>Cc1sc(C(C)C)nc1C(=O)N1CCOC2(CCN(Cc3cccc(CCO)c3F)CC2)C1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140113931A1,CC(C)C[C@@H](Nc1cnc(C#N)c(Nc2ccc3cnccc3c2)c1)C(N)=O.OO>>CC(C)C[C@@H](Nc1cnc(C(N)=O)c(Nc2ccc3cnccc3c2)c1)C(N)=O,,CCO,CS(C)=O,CC(=O)O,[Na+].[OH-],test
US06124338,Cc1cc(C(C)(C)C)cc(C)c1CC1=NCCN1>>Cc1cc(C(C)(C)C)cc(C)c1Cc1ncc[nH]1,[Pd],Cc1ccccc1,,,,test
US20090137557A1,COC(=O)C(CC(C)C)C(C)=O.N=C(N)c1cccc(F)c1OCc1ccccc1>>Cc1[nH]c(-c2cccc(F)c2OCc2ccccc2)nc(=O)c1CC(C)C,,C1COCCO1,CO,C[O-].[Na+],,test
US20100075948A1,CCC(C)(CC)CC(=O)OC>>CCC(C)(CC)CCO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04612309,CC(C)C(=O)OC(=O)C(C)C.COc1ccccc1OC>>COc1cccc(C(=O)C(C)C)c1OC,,CCCCCC,CCOCC,[Li]CCCC,,test
US20160229853A1,NC1CC2(C1)CS(=O)(=O)C2.O=[N+]([O-])c1cc(Cl)ccc1F>>O=[N+]([O-])c1cc(Cl)ccc1NC1CC2(C1)CS(=O)(=O)C2,,CN(C)C=O,O,CCN(CC)CC,O=C([O-])[O-].[K+].[K+],test
US20100137286A1,CCOC(=O)[C@@H]1CC[C@@H](Oc2ccncn2)CC1>>O=C(O)[C@@H]1CC[C@@H](Oc2ccncn2)CC1,,C1COCCO1,,[Na+].[OH-],,test
US20100240702A1,CC(C)(C)OC(=O)C(C)(C)Nc1ccccc1[N+](=O)[O-]>>CC(C)(C)OC(=O)C(C)(C)Nc1ccccc1N,[Pd],CCO,,,,test
US20120316151A1,CC1(C)OB(c2ccc3occc3c2)OC1(C)C.O=C(C1CC1)N1CC(Cc2n[nH]c(=O)n2-c2ccc(Br)cc2)C1>>O=C(C1CC1)N1CC(Cc2n[nH]c(=O)n2-c2ccc(-c3ccc4occc4c3)cc2)C1,,C1COCCO1,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20060025445A1,CCCS(=O)(=O)Cl.CCNC(C)C(=O)c1ccccc1>>CCCS(=O)(=O)N(CC)C(C)C(=O)c1ccccc1,,ClCCl,,O=C([O-])O.[Na+],,test
US20150259354A1,CCOC(=O)C1(NN)CCN(Cc2ccccc2)CC1.COC(=C(C#N)C#N)c1ccc(Oc2ccccc2)cc1>>N#Cc1c(-c2ccc(Oc3ccccc3)cc2)nn2c1NC(=O)C21CCN(Cc2ccccc2)CC1,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20070259851A1,CC(C)(C)OC(=O)N1CCC(Nc2cccc(F)c2C(=O)O)CC1.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3c(F)cccc32)CC1,,Cc1ccccc1,,CCN(CC)CC,,test
US20060122263A1,C1=CC[C@@H](C(c2ccccc2)c2ccccc2)OC1.O=C(OO)c1cccc(Cl)c1>>c1ccc(C(c2ccccc2)[C@@H]2C[C@H]3O[C@H]3CO2)cc1,,ClCCl,,O=S([O-])[O-].[Na+].[Na+],,test
US20150299121A1,C[C@H]1CN(Cc2cccc(N)c2Cl)CCN1C(=O)OC(C)(C)C.N#Cc1cccc(C(=O)Cl)c1>>C[C@H]1CN(Cc2cccc(NC(=O)c3cccc(C#N)c3)c2Cl)CCN1C(=O)OC(C)(C)C,,ClCCl,,c1ccncc1,,test
US07179823B1,CI.O=C(O)CCc1cn(Cc2ccc(OCc3ccccc3)cc2)nc1-c1ccccc1>>COC(=O)CCc1cn(Cc2ccc(OCc3ccccc3)cc2)nc1-c1ccccc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US06017919,CCCCCOc1c(OC)ccc2c(=O)n(CCc3ccc(N)cc3)c(=O)[nH]c12.Cl>>CCCCCOc1c(OC)ccc2c(=O)n(CCc3ccc(N)cc3)c(=O)[nH]c12.Cl,,CCO,,,,test
US20050239797A1,CCOC(=O)c1oc(C)nc1CC.CN1CCN(c2nccc3cc4c(cc23)NCC4)CC1>>CCc1nc(C)oc1C(=O)N1CCc2cc3ccnc(N4CCN(C)CC4)c3cc21,,Cc1ccccc1,,C[Al](C)C,,test
US20160255837A1,CCSc1nc(C(F)(F)F)ccc1C(=O)Cl.CNOC>>CCSc1nc(C(F)(F)F)ccc1C(=O)N(C)OC,,C1CCOC1,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20160068489A1,Cc1cc(C)c(C(=O)Cl)c(C)c1.Cc1nc(N)c(C)c(C)c1OCc1ccccc1>>Cc1cc(C)c(C(=O)Nc2nc(C)c(OCc3ccccc3)c(C)c2C)c(C)c1,,ClCCl,,CCN(CC)CC,,test
US04137310,Nc1cc(Cl)c([N+](=O)[O-])cc1Cl.Oc1ccccc1>>Nc1cc(Oc2ccccc2)c([N+](=O)[O-])cc1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160122343A1,COC(=O)C(C)O.Oc1ccc(Cc2ccccc2)cc1>>COC(=O)C(C)Oc1ccc(Cc2ccccc2)cc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06420375B1,CC(=O)c1ccc2c(c1)CCCC2.O=Cc1cccnc1>>O=C(/C=C/c1cccnc1)c1ccc2c(c1)CCCC2,,CO,,C[O-].[Na+],,test
US20160263093A1,CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3cc(C=O)ccc3c2)CC1.CCOC(=O)C1CCNCC1C>>CCOC(=O)C1CCN(Cc2ccc3cc(O[C@@H]4CC[C@@H](C(C)(C)C)CC4)ccc3c2)CC1C,,ClCCCl,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20090274655A1,COC(=O)c1sc(B(O)O)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C1CCC1.O=C(Nc1ccc(I)cc1)c1cscn1>>COC(=O)c1sc(-c2ccc(NC(=O)c3cscn3)cc2)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C1CCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US04014920,CC(=O)OC(C)=O.O=C(O)C=Cc1ccc(O)c(Cl)c1>>CC(=O)Oc1ccc(C=CC(=O)O)cc1Cl,,[Na+],[OH-],,,test
US20140080825A1,CCOC(=O)c1csc(NC(=O)OC(C)(C)C)n1.COc1ccccc1C=O>>CCOC(=O)c1nc(NC(=O)OC(C)(C)C)sc1C(O)c1ccccc1OC,,C1CCOC1,,[Li]CCCC,,test
US05006544,Cc1c(C=O)ncn1C(c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CCOc2ccccc21>>Cc1c(/C=C2\COc3ccccc3C2=O)ncn1C(c1ccccc1)(c1ccccc1)c1ccccc1,,CO,,[K+].[OH-],,test
US20030128496A1,CC(=O)[O-].CC(=O)[O-].[Pb+2]>>CC(=O)[O-].CC(=O)[O-].[Pb+2],,COCCO,,O,,test
US20050059726A1,CC(C)C(=O)Nc1ccc(N2CC[C@H](NC(=O)OC(C)(C)C)C2=O)c(F)c1>>CC(C)C(=O)Nc1ccc(N2CC[C@H](N)C2=O)c(F)c1,,CO,,CC(=O)Cl,,test
US20090192203A1,COC(=O)CC(N)=O.O=C(CBr)c1ccc(C(F)(F)F)cc1>>COC(=O)Cc1nc(-c2ccc(C(F)(F)F)cc2)co1,,O,,,,test
US20080009486A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C1CC(c2cccc(Cl)c2)C2(C(=O)Nc3cc(Cl)ccc32)C(c2ccc(F)c(F)c2)N1>>O=C1Nc2cc(Cl)ccc2C12C(c1cccc(Cl)c1)CC(=S)NC2c1ccc(F)c(F)c1,,Cc1ccccc1,,,,test
US20050176941A1,COC(OC)[C@]1(OCc2ccccc2)C[C@H](n2cc(C)c(=O)n(COCc3ccccc3)c2=O)O[C@]1(CO)COCc1ccccc1>>Cc1cn([C@H]2C[C@](CO)(OCc3ccccc3)[C@@](CO)(COCc3ccccc3)O2)c(=O)n(COCc2ccccc2)c1=O,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20140275011A1,Brc1ccc2cc[nH]c2c1.Fc1cccc(CBr)c1>>Fc1cccc(Cn2ccc3ccc(Br)cc32)c1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20040127574A1,O=C(O)C(Cc1ccc(C(F)(F)F)o1)C(O)c1ccc(F)cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>O=C1NC(Cc2ccc(C(F)(F)F)o2)C(c2ccc(F)cc2)O1,,C1CCOC1,,CCN(CC)CC,O,test
US20140228386A1,C1COCCO1.CN[C@@H]1CCCC[C@H]1NC.Cc1csc2cc(Br)c(F)cc12.O=C1NCCN1>>Cc1csc2cc(N3CCN(c4cnccc4C4CC4)C3=O)c(F)cc12,I[Cu]I,,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20100010217A1,CCCN(C)c1nc2c(N(Cc3ccc(OC)cc3)Cc3ccc(OC)cc3)nc3ccccc3c2n1CC(C)(C)O>>CCCN(C)c1nc2c(N)nc3ccccc3c2n1CC(C)(C)O,,O=C(O)C(F)(F)F,,CCOCC,,test
US20070021613A1,CC(=O)O.CCOC(=O)CC(=O)c1cc(F)c(Cl)nc1Cl.NC1CC1>>O=C(O)c1cn(C2CC2)c2nc(Cl)c(F)cc2c1=O,,Cc1ccccc1,,,,test
US20150284395A1,CCOC(=O)CC(=O)c1ccc2c(cnn2CC)c1.Cc1cnn(C)c1-c1cn[nH]c1N>>CCn1ncc2cc(-c3cc(=O)n4ncc(-c5c(C)cnn5C)c4[nH]3)ccc21,Cc1ccc(S(=O)(=O)O)cc1,CCCCO,,,,test
US20100256097A1,CC1(C)OB(c2ccc(S(C)(=O)=O)cc2)OC1(C)C.NC(=O)c1cc(Br)sc1[N+](=O)[O-]>>CS(=O)(=O)c1ccc(-c2cc(C(N)=O)c([N+](=O)[O-])s2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20070287739A1,COC(=O)c1cccc(C#Cc2c(-c3ccccc3)noc2C)c1>>Cc1onc(-c2ccccc2)c1C#Cc1cccc(C(=O)O)c1,,CCO,,[Na+].[OH-],,test
US20130338367A1,CC(C)(C)O.Cc1c(C(=O)O)cnn1-c1cccnc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cc1c(NC(=O)OC(C)(C)C)cnn1-c1cccnc1,,Cc1ccccc1,,CCN(CC)CC,,test
US05053509,CCOC(=O)c1cn(C)c2nc3cc(F)c(F)cc3cc2c1=O>>Cn1cc(C(=O)O)c(=O)c2cc3cc(F)c(F)cc3nc21,,CC(=O)O,,Cl,,test
US20140315911A1,COC(=O)[C@@H](C)N.O=[N+]([O-])c1cnc(Cl)nc1Cl>>COC(=O)[C@@H](C)Nc1nc(Cl)ncc1[N+](=O)[O-],,CCOCC,O,Cl,O=C([O-])[O-].[K+].[K+],test
US05212320,COC(=O)c1cccc(CCl)c1.c1ccc2c(c1)Nc1ccccc1O2>>COC(=O)c1cccc(CN2c3ccccc3Oc3ccccc32)c1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US04490369,COc1ccc(CCN(C)CCCN2CCc3cc(OC)c(OC)cc3CC2=O)cc1OC.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COc1ccc(CCN(C)CCCN2CCc3cc(OC)c(OC)cc3CC2=S)cc1OC,,Cc1ccccc1,,,,test
US20070225288A1,C1COCCN1.CCOC(=O)C1=C(c2ccccc2)c2ccc(OC)cc2C1Br>>CCOC(=O)C1=C(c2ccccc2)c2ccc(OC)cc2C1N1CCOCC1,,C1CCOC1,,,,test
US20080280906A1,CN(C)C(On1nnc2ccccc21)=[N+](C)C.CN(C)C=O.Cc1ncc(-c2ccnc(Nc3ccc(C(=O)[O-])cc3)n2)n1C(C)C.F[P-](F)(F)(F)(F)F.[Li+]>>CN(C)C(On1nnc2ccccc21)=[N+](C)C.CN(C)C=O.Cc1ncc(-c2ccnc(Nc3ccc(C(=O)[O-])cc3)n2)n1C(C)C.F[P-](F)(F)(F)(F)F.[Li+],,CN(C)C=O,,,,test
US05298518,CCCC(=O)O.Nc1nccc(Cl)c1N>>CCCc1nc2c(Cl)ccnc2[nH]1,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20080044687A1,CC1=NCCCC1.CSC1=NCCC1>>C(=C1CCCCN1)C1=NCCC1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20150148341A1,Brc1ccccn1.COC(=O)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C[C@@H]1CCN(C(=O)OC(C)(C)C)C2>>CC(C)(C)OC(=O)N1CC[C@H]2Cc3c(cnn3-c3ccc(F)cc3)C[C@]2(C(=O)c2ccccn2)C1,,C1CCOC1,,O,[Li]CCCC,test
US04927939,CSc1ccc(C(=O)c2sc(=O)[nH]c2C)cc1.OO>>Cc1[nH]c(=O)sc1C(=O)c1ccc(S(C)=O)cc1,,CC(=O)O,,O,,test
US20080113946A1,COc1ccc(OC)c(Nc2nc(SC)nc3c2CCC3)c1>>COc1ccc(OC)c(Nc2ncnc3c2CCC3)c1,[Ni],,,[H][H],,test
US20040106653A1,CCOC(=O)c1cc(S(=O)(=O)c2ccc(CCN(Cc3ccccc3)C(=O)C(F)(F)F)cc2)ccc1O>>CCOC(=O)c1cc(S(=O)(=O)c2ccc(CCNCc3ccccc3)cc2)ccc1O,,CCO,,Cl,,test
US20090118287A1,COC(=O)[C@@H]1C[C@@H](OCc2ccccc2)C1>>COC(=O)[C@H]1C[C@H](O)C1,[Pd],CO,,,,test
US04228170,CC(=O)N1CCc2ccc(S)cc2C1.CI>>CSc1ccc2c(c1)CN(C(C)=O)CC2,,CO,,C[O-].[Na+],,test
US20130150343A1,CC(C)[Si](OC[C@@]1(C(=O)O)CCCN1C)(C(C)C)C(C)C.NNc1ccc(F)cn1>>CC(C)[Si](OC[C@@]1(C(=O)NNc2ccc(F)cn2)CCCN1C)(C(C)C)C(C)C,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070032469A1,Nc1c(O)cc(Cl)cc1[N+](=O)[O-].O=C(Cl)CBr>>O=C1COc2cc(Cl)cc([N+](=O)[O-])c2N1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US06232290B1,CCCCOc1ccc(C(=O)NNC(N)=S)cc1>>CCCCOc1ccc(-c2nnc(N)s2)cc1,,Cc1ccccc1,,CS(=O)(=O)O,,test
US05349095,Brc1cccc2c1CC2.CN(C)C=O>>O=Cc1cccc2c1CC2,,C1CCOC1,,[Mg],[Cl-].[NH4+],test
US20080255106A1,COC(=O)c1ccc(C(=O)O)cc1.Nc1cccnc1N>>COC(=O)c1ccc(-c2nc3cccnc3[nH]2)cc1,,CC#N,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100041628A1,C1CSCCN1.CN(C)C=O.N#CC(C(N)=O)c1ccccc1NC(=O)c1ccccc1.[BH3-]C#N>>NC(=O)Nc1[nH]c2cc(CN3CCSCC3)ccc2c1C(N)=O,,CC(=O)O,O,O=C([O-])O.[Na+],,test
US03931209,C=O.CSc1nnc(NC(=O)N(C)N)s1>>CSc1nnc(N2CNN(C)C2=O)s1,,CO,,[K+].[OH-],,test
US20110312936A1,CCC(NC(=O)OC)C1CCC2(CC1)OCCO2>>CCC(NC(=O)OC)C1CCC(=O)CC1,,CC#N,,Cl,,test
US06376505B1,CN1CCC2(CC1)OC(=O)c1c2ccc2c1OCCO2>>CN1CCC2(CC1)OCc1c2ccc2c1OCCO2,,C1CCOC1,,B,Cl,test
US20090012093A1,COC(=O)CCc1ccc(O)cc1.O[C@@H]1CCc2ccccc21>>COC(=O)CCc1ccc(O[C@H]2CCc3ccccc32)cc1,,C1CCOC1,O,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US06350749B1,COc1ccccc1C1CC(=O)c2c(C)coc2C1.Cl.N=C(N)NN>>COc1ccccc1C1C/C(=N\NC(=N)N)c2c(C)coc2C1.Cl,,CCO,,Cl,,test
US06133287,CN1CC=C(c2c[nH]c3ccc(OC4CCCCC4)cc23)CC1>>CN1CCC(c2c[nH]c3ccc(OC4CCCCC4)cc23)CC1,[Pd],CO,,,,test
US20090197834A1,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].N#CCOc1cn(C2CCCC2)c2cc(NC3CCCCC3)c(F)cc2c1=O>>O=c1c(OCc2nnn[nH]2)cn(C2CCCC2)c2cc(NC3CCCCC3)c(F)cc12,,CCOCC,,C1COCCO1,[Na+].[OH-],test
US20120157458A1,O=C(O)C1=COCCC1>>O=C(O)C1CCCOC1,,CCO,,,,test
US04153719,COc1ccc(C=Cc2ccc(CO)cc2)cc1.COc1ccc(Cc2ccc(CBr)cc2)cc1>>COc1ccc(C=Cc2ccc(CBr)cc2)cc1,,ClCCl,,Br,,test
US20050026935A1,CCOC(=O)Cc1nc(NCc2ccccn2)c2c(-c3ccccc3)csc2n1>>OCCc1nc(NCc2ccccn2)c2c(-c3ccccc3)csc2n1,,C1CCOC1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20150018363A1,Cc1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cn12.OCc1ccc(F)c(F)c1>>Cc1c(C2CC2)nc2ccc(-n3ccc(OCc4ccc(F)c(F)c4)cc3=O)cn12,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US06162610,CC(C)(C)[Si](C)(C)Cl.Oc1ccc2c(c1)Cc1ccccc1O2>>CC(C)(C)[Si](C)(C)Oc1ccc2c(c1)Cc1ccccc1O2,CN(C)c1ccncc1,CN(C)C=O,,c1c[nH]cn1,,test
US20150284327A1,CC(=O)OC(C)=O.CCOC(OCC)(OCC)c1ccccc1.COC(=O)c1ccc2c(c1)NC(=O)C2>>CCOC(=C1C(=O)N(C(C)=O)c2cc(C(=O)OC)ccc21)c1ccccc1,,Cc1ccccc1,,,,test
US20140031349A1,BrBr.CCOC(=O)C(C)C(C)=O>>CCOC(=O)C(C)C(=O)CBr,,O,,,,test
US20110034464A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)Nc1ccc(Cl)cc1C#N>>COC(=O)Nc1ccc(Cl)cc1CNC(=O)OC(C)(C)C,Cl[Ni]Cl,CO,,[BH4-].[Na+],,test
US20100056516A1,O=c1cc(-c2cccc(CN3CCN(Cc4ccccc4)CC3)c2)c2cccnc2n1OCc1ccccc1>>O=c1cc(-c2cccc(CN3CCN(Cc4ccccc4)CC3)c2)c2cccnc2n1O,,CC(=O)O,,Br,O,test
US20120010228A1,CC(C)(C)OC(=O)C(C)(C)Oc1ccc(CN2CN(c3ccccc3)C3(CCNCC3)C2=O)cc1.O=c1[nH]c2ccccc2n1CCCI>>CC(C)(C)OC(=O)C(C)(C)Oc1ccc(CN2CN(c3ccccc3)C3(CCN(CCCn4c(=O)[nH]c5ccccc54)CC3)C2=O)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20060167107A1,CCCCCCCCCCCCCCCc1cccc(OC(C)C)c1C(=O)Cl.Nc1ccc([N+](=O)[O-])c(C(F)(F)F)c1>>CCCCCCCCCCCCCCCc1cccc(OC(C)C)c1C(=O)Nc1ccc([N+](=O)[O-])c(C(F)(F)F)c1,,ClCCl,,CCN(CC)CC,,test
US20090075973A1,CC(C)(S)CCO.O=C(O)c1ccc(F)c([N+](=O)[O-])c1>>CC(C)(CCO)Sc1ccc(C(=O)O)cc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070244159A1,CNc1ccc([N+](=O)[O-])cc1C#CC(C)(C)C>>Cn1c(C(C)(C)C)cc2cc([N+](=O)[O-])ccc21,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120270882A1,Cc1occc(=O)c1OCc1ccccc1.NCC(F)F>>Cc1c(OCc2ccccc2)c(=O)ccn1CC(F)F,,c1ccncc1,,CCN(CC)CC,Cl,test
US20110172442A1,COC(=O)[C@H](Cc1cn(C)c2ccccc12)NC(=O)C=Cc1ccc(F)cc1>>Cn1cc(C[C@H](NC(=O)C=Cc2ccc(F)cc2)C(=O)O)c2ccccc21,,CO,,[Na+].[OH-],,test
US05760031,CCOC(=O)Cn1cc2c(n1)-c1ccccc1N(C(=O)c1ccc(N)cc1)CC2.O=C(Cl)c1ccc(Cl)cc1Cl>>CCOC(=O)Cn1cc2c(n1)-c1ccccc1N(C(=O)c1ccc(NC(=O)c3ccc(Cl)cc3Cl)cc1)CC2,,ClCCl,,CCN(CC)CC,,test
US20040209865A1,COC(=O)c1cc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)ccc1OCCN1CCCC1>>O=C(O)c1cc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)ccc1OCCN1CCCC1,,CO,,Cl,[Na+].[OH-],test
US20150266895A1,CC(=O)OCc1nc(NC(=O)N[C@H](C)c2ccccc2)cc(Cl)c1C#N.NN>>C[C@@H](NC(=O)Nc1cc2[nH]nc(N)c2c(CO)n1)c1ccccc1,,CCO,,O,,test
US20110136780A1,CC[C@H](C)[C@@H](NCc1ccnc2c1c(C(=O)OC)cn2C(=O)OC(C)(C)C)C(=O)O.NC1CCCC1>>CC[C@H](C)[C@@H](NCc1ccnc2c1c(C(=O)OC)cn2C(=O)OC(C)(C)C)C(=O)NC1CCCC1,,C1CCOC1,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090111798A1,CCOC(=O)C1CCCC1=O.NCc1ccc(Cl)cc1>>CCOC(=O)C1=C(NCc2ccc(Cl)cc2)CCC1,CC(=O)O,CCO,,[BH3-]C#N.[Na+],,test
US20120165318A1,COC(=O)c1ccc2nc(-c3ccccc3)c(Br)nc2c1.Clc1cccc(C2CCNCC2)c1>>COC(=O)c1ccc2nc(-c3ccccc3)c(N3CCC(c4cccc(Cl)c4)CC3)nc2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20110028469A1,COC(=O)c1sccc1N.O=S(=O)(Cl)c1ccc(F)cc1Cl>>COC(=O)c1sccc1NS(=O)(=O)c1ccc(F)cc1Cl,,ClCCl,,c1ccncc1,,test
US20010021714A1,CN(C)c1cccc2c(S(=O)(=O)Cl)cccc12.Cc1noc(NS(=O)(=O)c2ccsc2C(N)=O)c1Br>>Cc1noc(NS(=O)(=O)c2ccsc2C(=O)NS(=O)(=O)c2cccc3c(N(C)C)cccc23)c1Br,,O,,[H-].[Na+],,test
US20050176775A1,CC(=O)OC(C)(C)C(=O)Cl.Cc1cc(OCc2ccc(F)cc2F)c(Cl)c(=O)n1Cc1ccc2c(c1)CCN2>>Cc1cc(OCc2ccc(F)cc2F)c(Cl)c(=O)n1Cc1ccc2c(c1)CCN2C(=O)C(C)(C)O,,C1CCOC1,CO,CCN(CC)CC,[Na+].[OH-],test
US20030095958A1,CC(C)(C)OC(=O)N1CCC(c2nc(O)cc(-c3ccccc3)n2)CC1.FC(F)(F)c1ccccc1CBr>>O=c1cc(-c2ccccc2)nc(C2CCNCC2)n1Cc1ccccc1C(F)(F)F,,CC(C)=O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20120094832A1,CCc1ccc(Br)cc1C1C(=O)C2C(C1=O)C1(C)C=CC2(C)O1>>CCc1ccc(Br)cc1C1C(=O)C2C(C1=O)C1(C)CCC2(C)O1,[Pd],CO,,,,test
US20030232821A1,CN1COCNC1=N[N+](=O)[O-].ClCc1ccc(Cl)nc1>>CN1COCN(Cc2ccc(Cl)nc2)C1=N[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05378720,CCN(CC)C(=O)c1ccccc1C(C)C.N.O=S=O>>CCN(CC)C(=O)c1c(C(C)C)cccc1S(N)(=O)=O,,C1CCOC1,CCOCC,[Li]C(C)CC,,test
US20050075367A1,CCOC(=O)Cc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1.CI>>CCOC(=O)Cc1ccc(N(C)C(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20020137766A1,CN(C(=O)OC(C)(C)C)C1C2CCC1CNC2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CN(C(=O)OC(C)(C)C)C1C2CCC1CN(C(=O)C(F)(F)F)C2,,Cc1ccccc1,,,,test
US03998958,CCN1CCCC1=N.O=C=Nc1cccc(Cl)c1>>CCN1CCCC1=NC(=O)Nc1cccc(Cl)c1,,c1ccccc1,,,,test
US04009175,CCN(O)CC.ClCc1nnc2n1-c1ccc(Br)cc1C(c1ccccn1)=NC2>>CCN(CC)Cc1nnc2n1-c1ccc(Br)cc1C(c1ccccn1)=NC2,,CN(C)C=O,,[H-].[Na+],,test
US20100216788A1,CC(C)(C)OC(=O)NCCn1ccc2ncnc(Cl)c21.Nc1ccc2c(ccn2Cc2cccc(OC(F)(F)F)c2)c1>>CC(C)(C)OC(=O)NCCn1ccc2ncnc(Nc3ccc4c(ccn4Cc4cccc(OC(F)(F)F)c4)c3)c21,,CC(C)O,,,,test
US20160031874A1,Cc1cccnc1Nc1nc(-c2ccccn2)cs1.O=C1CCC(=O)N1Br>>Cc1cccnc1Nc1nc(-c2ccccn2)c(Br)s1,,ClCCl,,,,test
US20140329822A1,Fc1cccc(Br)c1.c1cn[nH]c1>>Brc1cccc(-n2cccn2)c1,,CN(C)C=O,,[H-].[Na+],,test
US04452625,CC(=O)OC(C)=O.CC(C)(C)C(O)C(=CC1CCCCC1)n1cncn1>>CC(=O)OC(C(=CC1CCCCC1)n1cncn1)C(C)(C)C,,CC(=O)OC(C)=O,,c1ccncc1,O=C([O-])O.[Na+],test
US20120302641A1,Cc1cc(C(F)(F)F)ccc1-c1ccc(N)cc1Cl.FC(F)(F)c1ccc(CBr)c(Br)c1>>Cc1cc(C(F)(F)F)ccc1-c1ccc(NCc2ccc(C(F)(F)F)cc2Br)cc1Cl,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20030195169A1,COc1ccc(Cl)cc1[C@]1(F)C(=O)N(COC(=O)CCOP(=O)(OC(C)(C)C)OC(C)(C)C)c2cc(C(F)(F)F)ccc21>>COc1ccc(Cl)cc1[C@]1(F)C(=O)N(COC(=O)CCOP(=O)(O)O)c2cc(C(F)(F)F)ccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090247746A1,CCOC(=O)c1cc2cccc(N(C)S(=O)(=O)c3ccc([N+](=O)[O-])cc3)c2n1COC>>CCOC(=O)c1cc2cccc(NC)c2[nH]1,,CCO,,Cl,,test
US04775674,CCOC(=O)CCCOc1ccc([N+](=O)[O-])c(C=O)c1.CCOP(=O)(OCC)C1NC(=O)NC1=O>>CCOC(=O)CCCOc1ccc([N+](=O)[O-])c(C=C2NC(=O)NC2=O)c1,,CCO,,[Na],,test
US04481268,CCOC(=O)CCl.O=[N+]([O-])c1ccc(S)cc1>>CCOC(=O)CSc1ccc([N+](=O)[O-])cc1,,CCO,,[Na],,test
US20120208840A1,CC(C)c1cc(O)nc2ccccc12.O=P(Cl)(Cl)Cl>>CC(C)c1cc(Cl)nc2ccccc12,,Cc1ccccc1,,,,test
US07504412B2,Cc1c(C2CC2)nc2ccc([N+](=O)[O-])cn12.Cl.O=C(O)c1cnc(-c2ccc(F)cc2)cn1>>Cc1c(C2CC2)nc2ccc(NC(=O)c3cnc(-c4ccc(F)cc4)cn3)cn12.Cl,,CCOC(C)=O,,,,test
US20100093694A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(OS(=O)(=O)C(F)(F)F)cc12.O=C(O)c1cccc(B(O)O)c1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cccc(C(=O)O)c3)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US06093718,Cc1cc(N2CCC(C(=O)N3CCN(C(=O)OC(C)(C)C)CC3)CC2)ncn1.Cl>>Cc1cc(N2CCC(C(=O)N3CCNCC3)CC2)ncn1.Cl,,CCOC(C)=O,,,,test
US20130331419A1,CCC(C(C)=O)(c1ccc(Cl)cc1)n1ccc2c(NS(C)(=O)=O)cccc21.NO>>CCC(C(C)=NO)(c1ccc(Cl)cc1)n1ccc2c(NS(C)(=O)=O)cccc21,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20060135512A1,CCOC(=O)[C@@H]1CCCC[C@H]1N1CC(C)CC1=O>>CC1CC(=O)N([C@@H]2CCCC[C@H]2C(=O)O)C1,,C1CCOC1,,Cl,[Li+].[OH-],test
US20140255381A1,CCOC(=O)c1cc(-c2ccc(F)cc2)ns1.C[Mg]Br>>CC(C)(O)c1cc(-c2ccc(F)cc2)ns1,,C1CCOC1,,CCOCC,,test
US20150166480A1,CCOC(=O)c1ccc(-c2ccc(OCC3CCN(CC(F)(CC)CC)CC3)c(C#N)c2)cc1F>>CCC(F)(CC)CN1CCC(COc2ccc(-c3ccc(C(=O)O)c(F)c3)cc2C#N)CC1,,C1CCOC1,O,[Li]O,,test
US20090186879A1,Cc1cc(Br)ccc1N.S=C(Cl)Cl>>Cc1cc(Br)ccc1N=C=S,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20060194969A1,CCOC(=O)c1cc(O)c2nc(C)n(C)c2c1.Cc1ccc(C)c2c1CC(Br)C2O>>CCOC(=O)c1cc(O[C@@H]2c3c(C)ccc(C)c3C[C@H]2O)c2nc(C)n(C)c2c1,,CCO,O,O=C([O-])[O-].[K+].[K+],,test
US20110319378A1,CC[C@@H](CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)N1C(=O)[C@@](C)(C2CC2C(=O)OC)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1>>CC[C@@H](CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)N1C(=O)[C@@](C)(C2CC2C(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1,,C1CCOC1,,[Na+].[OH-],,test
US20150005302A1,CC(=O)OCC(=O)c1cnc2ccc(Cl)nc2c1N[C@@H]1CC[C@@H](CN(C)C)CC1>>CN(C)C[C@@H]1CC[C@@H](Nc2c(C(=O)CO)cnc3ccc(Cl)nc23)CC1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20060009511A9,CCCBr.N#Cc1cccc(O)c1>>CCCOc1cccc(C#N)c1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US03983136,CCCCCC=CC1C2CC(OC3CCCCO3)CC12>>CCCCCC=CC1C2CC(O)CC12,,CO,,O=C(O)C(=O)O,,test
US20110306607A1,O=C(OCc1ccccc1)N1CCC2(CC1)Oc1ncccc1-n1cccc12>>c1cnc2c(c1)-n1cccc1C1(CCNCC1)O2,[Pd],CO,,CC(=O)O,,test
US20100267728A1,C[C@H](CO)n1nnc2cc3c(=O)n([C@H](C)Cn4ncnn4)nnc3cc2c1=O.c1nnn[nH]1>>C[C@H](Cn1ncnn1)n1nnc2cc3c(=O)n([C@H](C)Cn4ncnn4)nnc3cc2c1=O,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020161230A1,CC(C)OC(C)C.COB(OC)OC.Cc1ccc(Cl)cc1>>Cc1ccc(B(O)c2ccc(C)cc2)cc1,,CC(C)OC(C)C,,[Li],,test
US06093732,C#CCOC.O=C(NCc1ccc(Cl)cc1)c1cnc2c(F)cc(I)cc2c1O>>COCC#Cc1cc(F)c2ncc(C(=O)NCc3ccc(Cl)cc3)c(O)c2c1,,CN(C)C=O,CO,CCN(CC)CC,,test
US20030087306A1,COc1cccc(C(=O)C2CCN(C(=O)OC(C)(C)C)CC2)c1OC>>COc1cccc(C(O)C2CCN(C(=O)OC(C)(C)C)CC2)c1OC,,CO,,Cl,[BH4-].[Na+],test
US04684724,CC(C)(ON=C(C(=O)NC1C(=O)NC1C#N)c1csc(NC(=O)CCl)n1)C(=O)OCc1ccc([N+](=O)[O-])cc1.OO>>CC(C)(ON=C(C(=O)N[C@@H]1C(=O)N[C@@H]1C(N)=O)c1csc(NC(=O)CCl)n1)C(=O)OCc1ccc([N+](=O)[O-])cc1,,CS(C)=O,,[Na+].[OH-],,test
US20030191190A1,COC(=O)C(Br)c1ccc(Cl)cc1.O>>COC(=O)C(=O)c1ccc(Cl)cc1,,CS(C)=O,,C[N+]1([O-])CCOCC1,,test
US03941821,CCOC(=O)C(O)c1ccc(-c2ccccc2O)cc1.CI>>CCOC(=O)C(O)c1ccc(-c2ccccc2OC)cc1,,O,,CN(C)C=O,[H-].[Na+],test
US20070106103A1,OC1(c2cc(-c3ccccc3)cc(-c3ccccc3)c2)c2ccccc2C(O)(c2cc(-c3ccccc3)cc(-c3ccccc3)c2)c2cc(-c3ccccc3-c3ccccc3)ccc21>>c1ccc(-c2cc(-c3ccccc3)cc(-c3c4ccccc4c(-c4cc(-c5ccccc5)cc(-c5ccccc5)c4)c4cc(-c5ccccc5-c5ccccc5)ccc34)c2)cc1,,C1CCOC1,,Cl,,test
US20140228569A1,Nc1ccc(I)cn1.[N-]=[N+]=Nc1ccc(C(=O)CBr)cc1>>[N-]=[N+]=Nc1ccc(-c2cn3cc(I)ccc3n2)cc1,,CC#N,,,,test
US06350761B1,CCOC(C)=N.N=C(N)c1ccc(O)c(C=CCN(C(=O)CCC(=O)O)c2ccc(OC3CCNCC3)c(C(F)(F)F)c2)c1>>CC(=N)N1CCC(Oc2ccc(N(CC=Cc3cc(C(=N)N)ccc3O)C(=O)CCC(=O)O)cc2C(F)(F)F)CC1,,CCO,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20100234351A1,c1ccc(COCC(COCc2ccccc2)OCCOC2CCCCO2)cc1>>OCCOC(COCc1ccccc1)COCc1ccccc1,,CO,,Cl,[Na+].[OH-],test
US20040039044A1,CC(C)(C)OC(=O)N1CCCC1CO>>CC(C)(C)OC(=O)N1CCC[C@H]1CO,,C1CCOC1,,CCN(CC)CC,CS(=O)(=O)Cl,test
US06582351B1,COc1ccc(C=O)cc1Br>>COc1ccc(CO)cc1Br,,C1CCOC1,CCO,[BH4-].[Na+],,test
US04260816,CCOC(=O)c1ccc(N(CCOc2ccc(C#N)c3ccccc23)C(=O)C(F)(F)F)cc1>>N#Cc1ccc(OCCNc2ccc(C(=O)O)cc2)c2ccccc12,,CCO,,[K+].[OH-],,test
US20040058945A1,CNC.O=[N+]([O-])c1ccc2nc(-c3cccc(F)c3)cc(Cl)c2c1>>CN(C)c1cc(-c2cccc(F)c2)nc2ccc([N+](=O)[O-])cc12,,CN1CCCC1=O,,O,,test
US20040204386A1,Br.Cc1ccc(N)cc1I>>Cc1ccc(Br)cc1I,Br[Cu]Br,O,,O=N[O-].[Na+],,test
US04952587,C1CCNCC1.C=Cc1nc(-c2cn(C)c3ccccc23)no1.O=C(O)C(=O)O>>Cn1cc(-c2noc(CCN3CCCCC3)n2)c2ccccc21.O=C(O)C(=O)O,,CCO,ClCCl,,,test
US20130053359A1,COc1cc(NC(=O)OCCN(C)[C@@H]2CC[C@@H](OC(=O)C(O)(c3cccs3)c3cccs3)CC2)c(Cl)cc1CO>>COc1cc(NC(=O)OCCN(C)[C@@H]2CC[C@@H](OC(=O)C(O)(c3cccs3)c3cccs3)CC2)c(Cl)cc1C=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04797399,O=C(Cn1c(=O)sc2ccccc21)N1CCNCC1>>O=c1[nH]c2ccccc2s1,,ClC(Cl)Cl,,CC(C)CCON=O,,test
US20140200227A1,CC(C)(C)OC(=O)N[C@H]1CCCN(c2c(NC(=O)c3csc(-c4c(F)cccc4F)n3)cnc3ccsc23)C1>>N[C@H]1CCCN(c2c(NC(=O)c3csc(-c4c(F)cccc4F)n3)cnc3ccsc23)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110006287A1,CC(C)=CCC[C@H](C)CC(O)C(=O)C[C@@H](C)CCC=C(C)C>>CC(C)=CCC[C@H](C)CC(=O)C(=O)C[C@@H](C)CCC=C(C)C,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20150232449A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@]1(c2ccccc2F)NC(=O)C(F)CC1(F)F>>CC(C)(C)OC(=O)N1C(=O)C(F)CC(F)(F)[C@@]1(C)c1ccccc1F,CN(C)c1ccncc1,C1CCOC1,CCOC(C)=O,,,test
US20100190688A1,CN(C(=O)OCC1c2ccccc2-c2ccccc21)C(COCc1ccccc1)C(=O)NC1CCCc2ccccc21>>CNC(COCc1ccccc1)C(=O)NC1CCCc2ccccc21,,CN(C)C=O,,CCNCC,,test
US20060205772A1,CI.O=C(NCC1CCCCC1)c1ccc([N+](=O)[O-])cc1>>CN(CC1CCCCC1)C(=O)c1ccc([N+](=O)[O-])cc1,,C1CCOC1,,[H-].[Na+],,test
US20050267095A1,BrC1CCCC1.OC1CCNCC1>>OC1CCN(C2CCCC2)CC1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US05472983,CC(C)(C)NC(=O)c1ccc([N+](=O)[O-])cc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)NC(=S)c1ccc([N+](=O)[O-])cc1,,Cc1ccccc1,,CCOC(C)=O,,test
US20110014186A1,CON(C)C(=O)c1ccc(Cl)c(S(N)(=O)=O)c1.Cc1nc2ccc(Br)cc2[nH]1>>Cc1nc2ccc(C(=O)c3ccc(Cl)c(S(N)(=O)=O)c3)cc2[nH]1,,C1CCOC1,,[Li]C(C)(C)C,,test
US06127376,CCOC(=O)CC(=O)c1ccccc1.NC(N)=S>>Oc1cc(-c2ccccc2)nc(S)n1,,CCO,,[Na],,test
US06858633B1,N#C[Cu]C#N.Nc1ccc(-c2nc3cc(F)ccc3s2)cc1I>>N#Cc1cc(-c2nc3cc(F)ccc3s2)ccc1N,,CN(C)C=O,,,,test
US20080114004A1,CC(C)O.CNN.Nc1ncnc(Nc2ccc3c(cnn3Cc3cccc(F)c3)c2)c1C=O>>CN(C)N=Cc1c(N)ncnc1Nc1ccc2c(cnn2Cc2cccc(F)c2)c1,,O,,,,test
US04826868,COc1ccc(-n2nc(CCC=O)cc2-c2ccc(Cl)cc2)cc1.NO>>COc1ccc(-n2nc(CCC=NO)cc2-c2ccc(Cl)cc2)cc1,,CCO,,Cl,c1ccncc1,test
US05101059,O=C=Nc1ccccc1.OCC1c2ccccc2Oc2ccccc21>>O=C(Nc1ccccc1)OCC1c2ccccc2Oc2ccccc21,CCN(CC)CC,c1ccccc1,,,,test
US20040186104A1,FC(F)(F)c1ccc(-c2cccnc2)cc1.OO>>[O-][n+]1cccc(-c2ccc(C(F)(F)F)cc2)c1,,CC(=O)O,,,,test
US06399629B1,NCCc1ccccc1.O=[N+]([O-])c1ccccc1Cl>>O=[N+]([O-])c1ccccc1NCCc1ccccc1,,ClCCCl,,,,test
US06271388B1,CCOC(N)=O.COC[C@H]1COC(=O)O1>>COC[C@H]1CNC(=O)O1,,CN(C)C=O,,[Cs+].[F-],,test
US20120214803A1,Nc1ccccc1.O=Cc1ccc2cccnc2c1[N+](=O)[O-]>>O=[N+]([O-])c1c(CNc2ccccc2)ccc2cccnc12,,CO,,[BH4-].[Na+],,test
US20060079521A1,COC(=O)c1ccc(OC)c2[nH]c(-c3ccc([N+](=O)[O-])cc3)nc12>>Nc1ccc(-c2nc3c(C(=O)O)ccc(O)c3[nH]2)cc1,[Pd],CCO,,[H][H],,test
US20090042896A1,CC(=O)/C=C/c1ccc(Cl)c(Cl)c1.COCN(Cc1ccccc1)C[Si](C)(C)C>>CC(=O)C1CN(Cc2ccccc2)CC1c1ccc(Cl)c(Cl)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110105460A1,CN.O=C(O)c1ncc(F)cc1F>>CNC(=O)c1ncc(F)cc1F,,C1CCOC1,,CO,,test
US20120053206A1,CCOC(=O)CC(=O)N(c1cc(C(F)(F)F)ccc1C(C)=O)C1CCOCC1>>CCOC(=O)c1c(C)c2ccc(C(F)(F)F)cc2n(C2CCOCC2)c1=O,,CCO,,[H-].[Na+],,test
US20070004704A1,COC(=O)c1ccc(Cl)cc1N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(OCc2ccccc2)cc1>>COC(=O)c1ccc(Cl)cc1N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(O)cc1,[Pd],CCOC(C)=O,,[H][H],,test
US20140128387A1,Cc1cc(N)c2c(c1-c1ccncc1)CC(C(C)O)O2>>Cc1cc(N)c2c(c1C1CCNCC1)CC(CO)O2,O=[Pt]=O,CC(=O)O,,,,test
US20100298325A1,CI.COc1cc(Nc2ccc(Oc3cccc(N4CCCC4)c3)cn2)ccc1F>>COc1cc(N(C)c2ccc(Oc3cccc(N4CCCC4)c3)cn2)ccc1F,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20020128477A1,CC(C)(C)OC(=O)N1CCC=C(Cc2cn(S(=O)(=O)c3ccccc3)c3ccc(F)cc23)C1.Cl>>Cl.O=S(=O)(c1ccccc1)n1cc(CC2=CCCNC2)c2cc(F)ccc21,,CO,,,,test
US20130059834A1,C[Si](C)(C)CCOCn1cc(C(=O)N[C@@H](C(=O)N2CCC(C#N)CC2)C2CC2)c2nc(-n3ncc4cc(Cl)c(Cl)cc43)cnc21>>N#CC1CCN(C(=O)[C@H](NC(=O)c2c[nH]c3ncc(-n4ncc5cc(Cl)c(Cl)cc54)nc23)C2CC2)CC1,,ClCCl,,NCCN,O=C(O)C(F)(F)F,test
US20160152599A1,COC(=O)c1c[nH]c2ccccc12.COc1ccc(C(=O)O)c(I)c1>>COC(=O)c1cn(-c2cc(OC)ccc2C(=O)O)c2ccccc12,I[Cu]I,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US06117841,BrC1C=CCCC1.CNC(CC(C)C)C(=O)NC(Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(C)(C)C>>CC(C)CC(C(=O)NC(Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)C1C=CCCC1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20150307450A1,CC(C)(C)C(=O)Cl.COc1ccc(C#N)cc1/C=C(\C#N)c1c[nH]c2ccc(Br)cc12>>COc1ccc(C#N)cc1/C=C(\C#N)c1cn(C(=O)C(C)(C)C)c2ccc(Br)cc12,,CCOC(C)=O,,C1CCOC1,[H-].[Na+],test
US20150018328A1,N#CC1(c2cc(Nc3nc(Cl)nc(Cl)n3)ccn2)CC1.NC1CCC(F)(F)C1>>N#CC1(c2cc(Nc3nc(Cl)nc(NC4CCC(F)(F)C4)n3)ccn2)CC1,,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US20080188565A1,CCCCC(Br)C(=O)OC.Cc1cc(O)ccc1F>>CCCCC(Oc1ccc(F)c(C)c1)C(=O)OC,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05260318,COC(=O)c1ccc(N2CCC(N(C)Cc3ccc(F)cc3)CC2)cc1>>CN(Cc1ccc(F)cc1)C1CCN(c2ccc(C(=O)O)cc2)CC1,,[Na+],[OH-],CCO,,test
US06124280,CC(NC(=O)c1ccccc1)C(c1ccc(O)c(CN2CCCCCC2)c1)c1ccc(O)c(CN2CCCCCC2)c1.O=C(O)C(=O)O>>CC(NC(=O)c1ccccc1)C(c1ccc(O)c(CN2CCCCCC2)c1)c1ccc(O)c(CN2CCCCCC2)c1.O=C(O)C(=O)O,,CCO,,CCOC(C)=O,,test
US05017701,BrC(c1ccccc1)c1ccccc1.Nc1nc2nc[nH]c2c(=S)[nH]1>>Nc1nc(SC(c2ccccc2)c2ccccc2)c2[nH]cnc2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130172339A1,COC(=O)c1cccc(N)c1.Cc1c(S(=O)(=O)Cl)sc2ccc(Br)cc12>>COC(=O)c1cccc(NS(=O)(=O)c2sc3ccc(Br)cc3c2C)c1,,ClCCl,,,,test
US04640708,CCC(=O)Cl.O=C1C=C(O)CC(c2cccc3ccccc23)C1>>CCC(=O)C1=C(O)CC(c2cccc3ccccc23)CC1=O,,ClCCCl,,,,test
US20030036558A1,CCOC(=O)Cl.COc1ccc(C(=O)O)c(O)c1.NCc1ccc(Br)cc1F>>COc1ccc2c(=O)n(Cc3ccc(Br)cc3F)c(=O)oc2c1,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20130190314A1,Cc1cc(-c2cn3nc(N4CCN(C=O)CC4)ccc3n2)c(C)s1.O=C1CCC(=O)N1I>>Cc1cc(-c2nc3ccc(N4CCN(C=O)CC4)nn3c2I)c(C)s1,,ClC(Cl)Cl,ClCCl,,,test
US20100029643A1,CCn1c(C(C)NC(=O)OC(C)(C)C)nc2cc(Br)ccc21.OB(O)c1ccccn1>>CCn1c([C@@H](C)NC(=O)OC(C)(C)C)nc2cc(-c3cccnc3)ccc21,,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20090176823A1,COC(=O)C1=C(OS(=O)(=O)C(F)(F)F)C[C@@H]2CC[C@H]1N2C(=O)OC(C)(C)C.OB(O)c1ccc(O)cc1>>COC(=O)C1=C(c2ccc(O)cc2)C[C@@H]2CC[C@H]1N2C(=O)OC(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20130317045A1,NC(=O)c1ccsc1NC(=O)C(F)(F)c1ccc(F)cc1>>Oc1nc(C(F)(F)c2ccc(F)cc2)nc2sccc12,,ClCCCl,,C[Si](C)(C)Cl,,test
US20020147229A1,CC(C)(C)OC(=O)N1CCCCC1=O.O=Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>CC(C)(C)OC(=O)N1CCCC(C(O)c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)C1=O,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US06133303,O=C1CCCc2cc(OCCn3ccnc3)ccc21.O=Cc1ccc([N+](=O)[O-])s1>>O=C1C(=Cc2ccc([N+](=O)[O-])s2)CCc2cc(OCCn3ccnc3)ccc21,,CC(=O)O,O,O=S(=O)(O)O,,test
US20020193402A1,N#C[C@@H]1C[C@@]2(c3ccccc3)[C@H](O)CC[C@@H]1N2Cc1ccccc1.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>N#C[C@@H]1C[C@@]2(c3ccccc3)[C@H](OC(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC[C@@H]1N2Cc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20080207654A1,BrBr.CCCc1nc(COC)cc(=O)n1Cc1ccc(-c2ccccc2C#N)cc1>>CCCc1nc(COC)c(Br)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US06392090B1,CC(C)(C)c1cc(C(=O)[O-])cc(C(C)(C)C)c1O>>CC(C)(C)c1cc(C(=O)O)cc(C(C)(C)C)c1O,,Cc1ccccc1C,,[Na+].[OH-],,test
US05021478,CC1(C)CC(O)CC(C)(C)N1OC1CCCCC1.CCOC(=O)C(=Cc1ccccc1)C(=O)OCC>>CCOC(=O)C(=Cc1ccccc1)C(=O)OC1CC(C)(C)N(OC2CCCCC2)C(C)(C)C1,,Cc1ccccc1,,,,test
US20120214803A1,COc1ccc(C(O)c2ccc3cccnc3c2[N+](=O)[O-])cc1>>COc1ccc(C(=O)c2ccc3cccnc3c2[N+](=O)[O-])cc1,O=[Mn]=O,ClCCl,,,,test
US20090105295A1,CC(C)(O)Cn1c(CON)nc2c(N)nc3ccccc3c21.O=C(Cl)C1CC1>>CC(C)(O)Cn1c(CONC(=O)C2CC2)nc2c(N)nc3ccccc3c21,,CN(C)C=O,,CCN(CC)CC,,test
US20050020684A1,CO[C@@H](Cc1ccc(C#CCCCOc2ccc(C(=O)c3ccc(F)cc3)cc2)cc1)C(=O)O.NO>>CO[C@@H](Cc1ccc(C#CCCCOc2ccc(C(=NO)c3ccc(F)cc3)cc2)cc1)C(=O)O,,CCO,,,,test
US20080242685A1,C#Cc1nc(-c2ccccc2)cc(Cl)c1N>>Clc1cc(-c2ccccc2)nc2cc[nH]c12,[Cu]I,CN(C)C=O,,O,,test
US20080090883A1,N#Cc1ccc(N2C(=O)[C@H]3[C@H]4C=C[C@H](C4)[C@H]3S2(=O)=O)cc1C(F)(F)F>>N#Cc1ccc(NS(=O)(=O)[C@@H]2[C@@H]3C=C[C@@H](C3)[C@@H]2CO)cc1C(F)(F)F,,C1CCOC1,CO,[BH4-].[Na+],[Cl-].[NH4+],test
US20050171195A1,COC(=O)Cc1ccc2cccnc2c1.N>>NC(=O)Cc1ccc2cccnc2c1,,CO,,,,test
US20130059834A1,C[C@@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(C)c4cc(Cl)ccc34)nc12)C(=O)N1CC(C#N)C1>>C[C@@H](NC(=O)c1c[nH]c2ncc(-c3nn(C)c4cc(Cl)ccc34)nc12)C(=O)N1CC(C#N)C1,,ClCCl,,NCCN,O=C(O)C(F)(F)F,test
US20150376225A1,CC1([C@H]2CCC3C4CC=C5C[C@@H](O)CC[C@]5(C)C4[C@@H](O)C[C@@]32C)OCCO1.O=C(OO)c1cccc(Cl)c1>>CC1([C@H]2CCC3C4CC5OC56C[C@@H](O)CC[C@]6(C)C4[C@@H](O)C[C@@]32C)OCCO1,,ClCCl,,,,test
US20120040954A1,CO.O=c1[nH]c(-c2ccncc2)nc2cc(F)cc(F)c12>>COc1cc(F)cc2nc(-c3ccncc3)[nH]c(=O)c12,,CC(=O)O,CN(C)C=O,O,C[O-].[Na+],test
US04091108,O=C(OO)c1cccc(Cl)c1.c1ccc2c(c1)Oc1ccc(-c3nnn[nH]3)cc1S2>>O=S1c2ccccc2Oc2ccc(-c3nnn[nH]3)cc21,,CC(C)=O,O,,,test
US20130040930A1,COc1cc(N2CCCS2(=O)=O)ccc1C(=O)N1CCN(c2ccc(C)cc2C)CC1>>Cc1ccc(N2CCN(C(=O)c3ccc(N4CCCS4(=O)=O)cc3O)CC2)c(C)c1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20090181963A1,CCn1nnc2c(N3CCOC[C@@H]3C)nc(-c3ccc(N)cc3)nc21.N#Cc1ccc(N)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCn1nnc2c(N3CCOC[C@@H]3C)nc(-c3ccc(NC(=O)Nc4ccc(C#N)cc4)cc3)nc21,,ClCCl,,CCN(CC)CC,,test
US20110021537A1,CCCOC(=O)Cl.O=C(OCc1ccccc1)N1CCNCC1>>CCCOC(=O)N1CCN(C(=O)OCc2ccccc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20080045554A1,CCCCCn1/c(=N/NC(=O)CNC(=O)OCc2ccccc2)[nH]c(=O)c2[nH]cnc21>>CCCCCn1c2nc[nH]c2c(=O)n2c(CNC(=O)OCc3ccccc3)nnc12,,Cc1ccccc1,,,,test
US20090137389A1,CCCNCCC.Cc1ccc(C(=O)O)cc1[N+](=O)[O-]>>CCCN(CCC)C(=O)c1ccc(C)cc1[N+](=O)[O-],,CCOC(C)=O,Cc1ccccc1,CN(C)C=O,O=S(Cl)Cl,test
US04656298,CCOC(OCC)P(=O)(CC(C[N+](=O)[O-])c1ccc(F)cc1)OCC>>CCOC(OCC)P(=O)(CC(CN)c1ccc(F)cc1)OCC,[Ni],CCO,,N,[H][H],test
US20150005279A1,CC(C)(C)OC(=O)N1CCC[C@@H](N2Cc3ccc(F)cc3C2=O)C1.Cl>>Cl.O=C1c2cc(F)ccc2CN1[C@@H]1CCCNC1,,CO,ClCCl,,,test
US20020052369A1,CCN(CC)CCCc1ccc2[nH]c(C=O)cc2c1.O=C1Cc2ccccc2N1>>CCN(CC)CCCc1ccc2[nH]c(C=C3C(=O)Nc4ccccc43)cc2c1,,CCO,,C1CCNCC1,,test
US05023338,CC1OC1(C)C.COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccccc1>>COC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NCC(C)(C)O,,ClCCl,,CCO,,test
US20130143940A1,Cn1nc(C#N)c(C(=O)c2ccc(F)cc2Cl)c1-c1c(F)cccc1F>>Cn1nc(C#N)c(C(O)c2ccc(F)cc2Cl)c1-c1c(F)cccc1F,,CCO,,Cl,[BH4-].[Na+],test
US04409228,CC(=O)NC1CCNCC1.COc1cccc(Cl)n1>>COc1cccc(N2CCC(NC(C)=O)CC2)n1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050234036A1,CCOC(OCC)OCC.Nc1c(N)n(CC2CCCCC2)c(=S)[nH]c1=O>>O=c1[nH]c(=S)n(CC2CCCCC2)c2nc[nH]c12,,CCCCCCC,,,,test
US20100137308A1,COCCN.COc1cc(C(=O)O)cc([N+](=O)[O-])c1>>COCCNC(=O)c1cc(OC)cc([N+](=O)[O-])c1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US06277847B1,CC(C)N1Cc2c(N)cccc2C1=O.O=C1CCC(=O)N1Cl>>CC(C)N1Cc2c(N)ccc(Cl)c2C1=O,,CN(C)C=O,,O,,test
US20160235752A1,NNc1ccc([N+](=O)[O-])cc1.O=CC1C(=O)NC(=O)NC1=O>>O=C1NC(=O)C(/C=N/Nc2ccc([N+](=O)[O-])cc2)C(=O)N1,,CO,,,,test
US20150119405A1,CC1(C)C[C@H](O)[C@@H](NC(=O)OCC[Si](C)(C)C)CO1.CS(=O)(=O)Cl>>CC1(C)C[C@H](OS(C)(=O)=O)[C@@H](NC(=O)OCC[Si](C)(C)C)CO1,,ClCCl,,CCN(CC)CC,,test
US20040127576A1,CCCC[C@H]1CC(=O)[C@@H](C)[C@@H]2c3ccc(OCc4ccccc4)cc3CC[C@@]12C>>CCCC[C@H]1CC(=O)[C@@H](C)[C@@H]2c3ccc(O)cc3CC[C@@]12C,[Pd],CC(=O)O,,C1CCOC1,,test
US20030229079A1,CC(=O)c1cccc(Cc2ccccc2)c1.CCOC(=O)c1nncn1C(c1ccccc1)(c1ccccc1)c1ccccc1>>O=C(CC(=O)c1nncn1C(c1ccccc1)(c1ccccc1)c1ccccc1)c1cccc(Cc2ccccc2)c1,,C1CCOC1,,C,C[O-].[Na+],test
US20150087646A1,COc1cc(-n2nc(-c3c(F)cccc3Cl)[nH]c2=O)ccc1C(=O)O.NCc1ccccc1C(F)(F)F>>COc1cc(-n2nc(-c3c(F)cccc3Cl)[nH]c2=O)ccc1C(=O)NCc1ccccc1C(F)(F)F,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20150126449A1,N#Cc1c(F)cc(F)cc1Br.NN>>Nc1n[nH]c2cc(F)cc(Br)c12,,CCO,,O,,test
US20070185079A1,CN(C)C=O.c1cnc2c(c1)ccc1cc[nH]c12>>O=Cc1c[nH]c2c1ccc1cccnc12,,O,,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US04399134,C1CCNCC1.CC(=O)c1cn2c3c(c(Cl)c(F)cc3c1=O)CCC2C>>CC(=O)c1cn2c3c(c(N4CCCCC4)c(F)cc3c1=O)CCC2C,,CN(C)P(=O)(N(C)C)N(C)C,,,,test
US20040029874A1,CC(C)=O.Cc1ccc(NCC2CCNCC2)c(C(=O)Nc2ccc(Cl)cn2)c1>>Cc1ccc(NCC2CCN(C(C)C)CC2)c(C(=O)Nc2ccc(Cl)cn2)c1,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US20090131468A1,NS(=O)(=O)c1ccccc1S(N)(=O)=O.O=C(O)C1CCC(c2cc3ccccc3o2)CC1>>NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)C1CCC(c2cc3ccccc3o2)CC1,CN(C)c1ccncc1,CN(C)C=O,,CCN=C=NCCCN(C)C,Cl,test
US20070015744A1,CC(C)(C)OC(=O)N1CCN(c2cccc(F)c2[N+](=O)[O-])CC1.NCc1ccccc1>>CC(C)(C)OC(=O)N1CCN(c2cccc(NCc3ccccc3)c2[N+](=O)[O-])CC1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030171581A1,C1COCCN1.N#Cc1ccc(Cl)cc1>>N#Cc1ccc(N2CCOCC2)cc1,,O,,,,test
US20030069428A1,CC(=O)OC1CC(N2C(=O)c3cccc(NC(=O)c4ccccc4)c3C2=O)C(=O)NC1=O>>O=C(Nc1cccc2c1C(=O)N(C1CC(O)C(=O)NC1=O)C2=O)c1ccccc1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20070066663A1,CC(C)(C)OC(=O)N1CCC[C@H](NC2CCCC2)C1.FC(F)(F)c1ccccc1CBr>>CC(C)(C)OC(=O)N1CCC[C@H](N(Cc2ccccc2C(F)(F)F)C2CCCC2)C1,,CC#N,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US04057647,CCOC(=O)CC(C)=O.Fc1ccc(-c2ccc(Br)cc2)c(F)c1>>CCOC(=O)CC(C)(O)c1ccc(-c2ccc(F)cc2F)cc1,,CCOCC,,[Mg],[Cl-].[NH4+],test
US20050153981A1,COc1ccc(CNC(=O)CCl)cc1.Cl.Cl.O=C(CN1CCNCC1)c1ccccc1>>COc1ccc(CNC(=O)CN2CCN(CC(=O)c3ccccc3)CC2)cc1.Cl.Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100113422A1,CC(C)(C)OC(=O)N1CCc2nc(Cc3ccc(F)cc3)nc(OS(=O)(=O)C(F)(F)F)c2CC1.CN>>CNc1nc(Cc2ccc(F)cc2)nc2c1CCN(C(=O)OC(C)(C)C)CC2,,CC(=O)N(C)C,,C1CCOC1,,test
US20080039456A1,CCOC(=O)CC(C)(C)CN1C(=O)c2cc3oc(-c4ccc([N+](=O)[O-])cc4)cc3n2C1=S>>CC(C)(CC(=O)O)CN1C(=O)c2cc3oc(-c4ccc([N+](=O)[O-])cc4)cc3n2C1=S,,O=C(O)C(F)(F)F,,O,,test
US05034047,CC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cc(C2CCCCO2)no1>>CC(=O)C=Cc1cc(C2CCCCO2)no1,,ClCCl,,,,test
US20110144131A1,CCOC(=O)C1CCN(C(C)C)CC1.NN>>CC(C)N1CCC(C(=O)NN)CC1,,CCO,,O,,test
US20060135525A1,CCOC(=O)CC(=O)C(F)(F)F.CCOC([O-])[O-].NC(N)=O>>CCOC(=O)c1cnc(O)nc1C(F)(F)F,,Cc1ccccc1C,,,,test
US20090270381A1,Cl[Mg]Cc1ccccc1.N#Cc1ccc(NC(=O)C(=O)C2CCCCC2)cc1Cl>>N#Cc1ccc(NC(=O)C(O)(Cc2ccccc2)C2CCCCC2)cc1Cl,,C1CCOC1,,,,test
US20050026968A1,N#Cc1ccc(N2CCN(Cc3ccccc3)CC2)cc1.O=C(Cl)c1ccc([N+](=O)[O-])o1>>O=C(NCc1ccc(N2CCN(Cc3ccccc3)CC2)cc1)c1ccc([N+](=O)[O-])o1,,ClCCl,,CCN(CC)CC,,test
US20040072832A1,Cc1c(O)cn2ncnc(Oc3ccccc3)c12.OCCCN1CCCCC1>>Cc1c(OCCCN2CCCCC2)cn2ncnc(Oc3ccccc3)c12,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030100770A1,CC(C)(C)OC(=O)[C@H]1CCCN1C(=O)COc1cc(C#N)cc(OCC(=O)N2CCC[C@@H]2C(=O)OC(C)(C)C)c1>>N#Cc1cc(OCC(=O)N2CCC[C@@H]2C(=O)O)cc(OCC(=O)N2CCC[C@@H]2C(=O)O)c1,,O=C(O)C(F)(F)F,,,,test
US20130178460A1,CC1C=CC(NC(=O)c2csc3cnc(N[C@@H]4CCOC[C@@H]4NC(=O)OC(C)(C)C)nc23)=CC1>>Cc1ccc(NC(=O)c2csc3cncnc23)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20160158207A1,CC(=O)N1CCc2c(c(N3CCCc4cc(Br)c(C#N)cc43)nn2C2CCOCC2)C1.CC(OS(C)(=O)=O)C1CC1>>C/C=C/CCn1nc(Nc2cccc(C)c2)c2c1CCN(C(C)=O)C2,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20090012054A1,CC(C)(C)OC(=O)N/C=C(\CNC(=O)OC(C)(C)C)c1cnn2c1NCCC2>>CC(C)(C)OC(=O)NCC(CNC(=O)OC(C)(C)C)c1cnn2c1NCCC2,[Pd],C1CCOC1,CO,,,test
US20070129347A1,CC(Cc1c[nH]c2ccccc12)NC(=O)C=C1CCC(c2cccc(F)c2)(N(C)C)CC1.C[Si](C)(C)Cl>>CC(Cc1c[nH]c2ccccc12)NC(=O)C=C1CCC(c2cccc(F)c2)(N(C)C)CC1.Cl,,CCC(C)=O,,,,test
US20150045401A1,Nc1nc2ccc(OC(F)(F)F)cc2s1.O=C1CCC(=O)O1>>O=C(O)CCC(=O)Nc1nc2ccc(OC(F)(F)F)cc2s1,,C1CCOC1,,CCN(CC)CC,CN(C)C=O,test
US20130116234A1,CCOC(=O)CC(=O)C1CC1.Nc1ccc(Cl)cc1C#Cc1ccccc1Cl>>CCOC(=O)c1c(C2CC2)nc2ccc(Cl)cc2c1Cc1ccccc1Cl,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05665718,CCOC(=O)c1ncn2c1[C@@H]1CCN1C(=O)c1cc(Cl)ccc1-2>>O=C(O)c1ncn2c1[C@@H]1CCN1C(=O)c1cc(Cl)ccc1-2,,CCO,,[Na+].[OH-],,test
US06486155B1,Brc1ccccn1.COC(=O)c1c(-c2cc(OC)c(OC)c(OC)c2)c2cc(OC)c(O)cc2c(=O)n1-c1ccc(NC(=O)OC(C)(C)C)cc1>>COC(=O)c1c(-c2cc(OC)c(OC)c(OC)c2)c2cc(OC)c(Oc3ccccn3)cc2c(=O)n1-c1ccc(NC(=O)OC(C)(C)C)cc1,I[Cu]I,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150266872A1,FC(F)(F)c1cc(-c2cnco2)c2cc[nH]c2c1.O=C(Cl)C1CC1>>O=C(C1CC1)n1ccc2c(-c3cnco3)cc(C(F)(F)F)cc21,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20020133007A1,COc1c(Cl)cc(F)c(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c1N>>Cn1c(C(F)(F)F)cc(=O)n(-c2c(F)cc(Cl)c(O)c2N)c1=O,,ClCCCl,,ClCCl,,test
US06815455B1,BrC(Br)(Br)Br.Cc1ccc2nc(SCCCCCO)[nH]c2c1>>Cc1ccc2nc(SCCCCCBr)[nH]c2c1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060258725A1,CI.COC(=O)c1cccc(S(=O)(=O)Nc2ccc(OCc3c(-c4c(Cl)cccc4Cl)noc3C(C)C)cc2C)c1>>COC(=O)c1cccc(S(=O)(=O)N(C)c2ccc(OCc3c(-c4c(Cl)cccc4Cl)noc3C(C)C)cc2C)c1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100035916A1,CCOC(=O)CCC1(c2ccc(OC)nc2)CCC(=O)NC1>>COc1ccc(C2(CCCO)CCCNC2)cn1,,C1CCOC1,,[H-].[Na+],,test
US06310056B1,C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(c3cn4c(CO[Si](C)(C)C(C)(C)C)ncc4s3)[C@H](C)[C@H]12>>C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(c3cn4c(CO)ncc4s3)[C@H](C)[C@H]12,,C1CCOC1,,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20130012499A1,COC(=O)c1c(C)c(-c2cccc(C(F)(F)F)c2)nc2cc(OC)c(S(=O)(=O)C(C)C)cc12.O=C1CCC(=O)N1Br>>COC(=O)c1c(CBr)c(-c2cccc(C(F)(F)F)c2)nc2cc(OC)c(S(=O)(=O)C(C)C)cc12,,ClC(Cl)(Cl)Cl,,,,test
US20070249670A1,COC(=O)[C@@H](NC(=O)c1ccc(Cl)cc1N)C1CCCCC1.Cc1cc(C)c(N=C=O)c(C)c1>>COC(=O)[C@@H](NC(=O)c1ccc(Cl)cc1NC(=O)Nc1c(C)cc(C)cc1C)C1CCCCC1,,c1ccncc1,,CCCCCC,CCOC(C)=O,test
US20140315888A1,CCOP(=O)(OCC)C(F)(F)Br.CN(C(=O)OC(C)(C)C)C1CN(c2nc3ncc(O)cc3n3cnnc23)C1>>CNC1CN(c2nc3ncc(OC(F)F)cc3n3cnnc23)C1,,CC#N,O,[K+].[OH-],,test
US20030191160A1,CC(C)=CCBr.Cc1cccc2nc(-c3c(F)cccc3F)[nH]c12>>CC(C)=CCn1c(-c2c(F)cccc2F)nc2c(C)cccc21,,C1CCOC1,,[H-].[Na+],,test
US20120046267A1,CC(C)(C)OC(=O)N1CC(n2cc(-c3cnc(N)c4oc(-c5cccc6cnccc56)cc34)cn2)C1>>Nc1ncc(-c2cnn(C3CNC3)c2)c2cc(-c3cccc4cnccc34)oc12,,ClCCl,,Cl,,test
US20140350019A1,CCOC(=O)CBr.Nc1c(F)ccc(O)c1F>>CCOC(=O)COc1ccc(F)c(N)c1F,,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US06214869B1,CS(=O)(=O)Cl.OC[C@@H]1C[C@@H]1c1cccc2c1CCO2>>CS(=O)(=O)OC[C@@H]1C[C@@H]1c1cccc2c1CCO2,,ClCCl,,CCN(CC)CC,,test
US20070021450A1,CC(=O)O.Nc1ccc(CCC(=O)O)cc1>>CC(=O)Nc1ccc(CCC(=O)O)cc1,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20100125062A1,CC1(C)OB(C2=CCOCC2)OC1(C)C.O=C(c1ccc(Oc2ncccc2Br)cc1)c1nc2ncccc2[nH]1>>O=C(c1ccc(Oc2ncccc2C2=CCOCC2)cc1)c1nc2ncccc2[nH]1,,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20070249688A1,Cc1cc(SC(=O)N(C)C)cc(C)c1Br>>Cc1cc(S)cc(C)c1Br,,CCOC(C)=O,CO,Cl,C[O-].[Na+],test
US04264620,C[C@H](CSC(=O)c1ccccc1)C(=O)N1C(C(=O)O)CCC1c1ccccc1>>C[C@H](CS)C(=O)N1C(C(=O)O)CCC1c1ccccc1,,CO,,N,,test
US04582849,CC(CN)Cc1ccc(C(C)(C)C)cc1.O=C1OC(=O)C(Cl)=C1Cl>>CC(CN=C(O)/C(Cl)=C(/Cl)C(=O)O)Cc1ccc(C(C)(C)C)cc1,,CC(=O)O,,O,,test
US20120190677A1,C=C(C)C.CCc1ccccc1C=O.COC(=O)c1ccc(N)cc1>>CCc1ccccc1C1CC(C)(C)c2cc(C(=O)OC)ccc2N1,,CC#N,CCOC(C)=O,O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3],,test
US04329281,CC(=O)OC(C)=O.CC(N)Cc1ccccc1>>CC(=O)NC(C)Cc1ccccc1,,O,,O=S(=O)(O)O,[Na+].[OH-],test
US20030045558A1,CCOC(=O)C(C)(C)Oc1ccc(OCc2ccccc2)cc1-c1ccccc1>>CC(C)(Oc1ccc(O)cc1-c1ccccc1)C(=O)O,[Pd],CCO,,[H][H],,test
US20070015773A1,BrBr.CC(NC(=O)OCc1ccccc1)c1cc(=O)n2cc(F)ccc2n1>>CC(NC(=O)OCc1ccccc1)c1nc2ccc(F)cn2c(=O)c1Br,,CC(=O)O,,O,,test
US20090176823A1,CN(C)C=O.Cc1ccc(Cl)cc1Br>>Cc1ccc(Cl)cc1C=O,,C1CCOC1,,[Li]CCCC,,test
US04764623,Nc1ccc(CCO)cc1.O=C(Cl)C(F)(F)C(F)(F)C(F)(F)F>>O=C(Nc1ccc(CCO)cc1)C(F)(F)C(F)(F)C(F)(F)F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080207654A1,CCCc1nc(CC)c(-c2ccc(OC(F)(F)F)cc2)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCc1nc(CC)c(-c2ccc(OC(F)(F)F)cc2)c(=O)n1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,O,,CS(C)=O,[Cl-].[Na+],test
US20120136002A1,CC(=O)N(O)C(=N)c1ccc(Oc2ccc(NS(=O)(=O)c3ccc(F)cc3)c(Oc3ccc(C(=N)N(O)C(C)=O)cc3)n2)cc1.CO>>N=C(N)c1ccc(Oc2ccc(NS(=O)(=O)c3ccc4ccccc4c3)c(Oc3ccc(C(=N)N)cc3)n2)cc1,[Pd],CO,,,,test
US20020103371A1,COc1ccc(CN2Cc3c(-c4nc(C5CC5)no4)ncn3-c3ccc(C)cc3C2=O)c(OC)c1>>Cc1ccc2c(c1)C(=O)NCc1c(-c3nc(C4CC4)no3)ncn1-2,,ClCCl,O=C(O)C(F)(F)F,O=S(=O)(O)C(F)(F)F,,test
US20100261698A1,Cn1c(-c2cncc(CN3C(=O)c4ccccc4C3=O)c2)c(C#N)c2ccc(Cl)cc21>>Cn1c(-c2cncc(CN)c2)c(C#N)c2ccc(Cl)cc21,,CCO,,NN,,test
US04906634,CCN(CC)[C@@H]1CCCC[C@H]1Oc1ccc(N)cc1.CS(=O)(=O)OS(C)(=O)=O>>CCN(CC)[C@@H]1CCCC[C@H]1Oc1ccc(NS(C)(=O)=O)cc1.CS(=O)(=O)O,,CC#N,,,,test
US05686424,COc1cc(C(=O)CC2(NC(=O)[C@@H]3CCCN3)CCCCC2)cc(OC)c1OC.Cl>>COc1cc(C(=O)CC2(NC(=O)[C@@H]3CCCN3)CCCCC2)cc(OC)c1OC.Cl,,CCOCC,,,,test
US20100076014A1,CC(=O)OC(c1ccccc1)c1ccc2[nH]ncc2c1.COC(=Cc1ccccc1)O[Si](C)(C)C>>COC(=O)C(c1ccccc1)C(c1ccccc1)c1ccc2[nH]ncc2c1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20070298501A1,O=[N+]([O-])c1c(Cl)c(Cl)c(Cl)c2c1oc1c([N+](=O)[O-])c(Cl)c(Cl)c(Cl)c12>>Nc1c(Cl)c(Cl)c(Cl)c2c1oc1c(N)c(Cl)c(Cl)c(Cl)c12,,CCO,,,,test
US20100076022A1,CCCO.Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1>>CCCO.Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1,,CCCO,,,,test
US20050256123A1,CCC(=O)N(C)N.CCOC(=O)C(=O)C(=O)OCC>>CCOC(=O)C(=NN(C)C(=O)CC)C(=O)OCC,,Cc1ccccc1,,,,test
US20130109649A1,CC(C)=O.COc1ccc(CC(=O)N2C(=O)OC[C@@H]2Cc2ccccc2)cc1Br>>COc1ccc([C@H]2CNC(=O)OC2(C)C)cc1Br,Cl[Ti](Cl)(Cl)Cl,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110034659A1,C=COCCCl.CO[SiH](OC)OC>>CO[Si](CCOCCCl)(OC)OC,[Pt],,,,,test
US05264454,CCOC(=O)c1c(-c2ccccc2C)c2cc3c(cc2oc1=O)CCC3>>Cc1ccccc1-c1c(C(=O)O)c(=O)oc2cc3c(cc12)CCC3,,O,,CC(=O)O,Cl,test
US20060111375A1,COc1cc2c(Oc3cc(C)c(C)nc3-c3cccc(C)n3)ccnc2cc1O.ClCCBr>>COc1cc2c(Oc3cc(C)c(C)nc3-c3cccc(C)n3)ccnc2cc1OCCCl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050107364A1,CC(C)(C)OC(=O)CS(=O)(=O)Cl.CC1(CCC2CC2)C(=O)C(C2=NS(=O)(=O)c3cc(N)ccc3N2)=C(O)c2ccccc21>>CC(C)(C)OC(=O)CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)c3ccccc3C(C)(CCC3CC3)C1=O)N2,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04053312,CCC(C)(C)c1ccc(OCCCCc2c(O)c(N=Nc3ccc(OC)cc3)c3ccccc3c2C(N)=O)c(C(C)(C)CC)c1>>CCC(C)(C)c1ccc(OCCCCc2c(O)c(N)c3ccccc3c2C(N)=O)c(C(C)(C)CC)c1,,O,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20050239872A1,CC(C)OC(=O)CCCCCCN1C(=O)CC[C@@H]1CC[C@@H](O)C(F)(F)c1ccccc1>>O=C(O)CCCCCCN1C(=O)CC[C@@H]1CC[C@@H](O)C(F)(F)c1ccccc1,,CO,,Cl,[Li+].[OH-],test
US20100216836A1,Brc1cccnc1.OB(O)c1ccc2c(c1)OCO2>>c1cncc(-c2ccc3c(c2)OCO3)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20090124619A1,CC(C)(C)OC(=O)N1CCCC(CN)C1.CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NCC1CCCN(C(=O)OC(C)(C)C)C1,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20060252812A1,C=C(C)CBr.Oc1cc(OCc2ccccc2)ccc1Br>>C=C(C)COc1cc(OCc2ccccc2)ccc1Br,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05801183,COC(=O)c1ncccc1N.O=C(Cl)Cc1ccccc1>>COC(=O)c1ncccc1NC(=O)Cc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US04230707,CCOC(=O)c1cc(CC)sc1N.NC(=O)c1ccc(Cl)nc1>>CCc1cc2c(=O)n3cc(C(N)=O)ccc3nc2s1,,ClC(Cl)Cl,,,,test
US20150045349A1,Nc1n[nH]c2c(Br)cn(-c3ccccc3Cl)c(=O)c12.OB(O)c1ccccc1F>>Nc1n[nH]c2c(-c3ccccc3F)cn(-c3ccccc3Cl)c(=O)c12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20100130738A1,CI.COCn1c(C(F)(F)F)nc2c(C(=O)C(C)C(=O)OC)ccc(OC)c21>>COCn1c(C(F)(F)F)nc2c(C(=O)C(C)(C)C(=O)OC)ccc(OC)c21,,CN(C)C=O,O,[H-].[Na+],[Cl-].[NH4+],test
US20110076291A1,BrBr.O=C1CCCOc2ccc(F)cc21>>O=C1c2cc(F)ccc2OCCC1Br,,CCOCC,,,,test
US20040138106A1,CC(=O)c1ccc(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)cc1>>CC(=O)c1ccc(C[C@H](N)C(=O)O)cc1,,O,,C1CCNCC1,,test
US20150284401A1,Clc1nc(Cl)c(Cl)c(Cl)c1Cl.O=C(O)C(F)(F)F.O=S(=O)(O)C(F)(F)F>>F[n+]1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl.O=S(=O)([O-])C(F)(F)F,,O=C(O)C(F)(F)F,,N#N,,test
US20040092598A1,COC(=O)C=Cc1cccc(NC(=O)C=Cc2ccccc2)c1.NO>>O=C(C=Cc1cccc(NC(=O)C=Cc2ccccc2)c1)NO,,CO,O,Cl,[Na+].[OH-],test
US20130317024A1,CCn1c(Br)cc(C(=O)O)c1C(Nc1cc(Cl)ccc1C)c1ccc(Cl)cc1>>CCn1c(Br)cc2c1C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O,,O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20160068489A1,Cc1nc(NC(=O)C(C)(C)C)c(C)c(C)c1OCc1ccccc1>>Cc1nc(NC(=O)C(C)(C)C)c(C)c(C)c1O,[Pd],,,CO,,test
US04199510,CC(=O)NC1CCCc2sccc21.O>>CC(=O)NC1CCC(=O)c2sccc21,,CC(=O)O,,,,test
US20110112103A1,CCOC(=O)CNC(=O)c1nc(CC2CCN(c3ccc(C(C)(C)C)cc3)CC2)nc(C)c1OCc1ccccc1>>CCOC(=O)CNC(=O)c1nc(CC2CCN(c3ccc(C(C)(C)C)cc3)CC2)nc(C)c1O,[Pd],CCOC(C)=O,,,,test
US20110105562A1,C#CC[C@H](NC(=O)OC(C)(C)C)C(=O)O.CC(C)(C)OC(=O)N1CCC(Oc2cccc(C#CCCCN)c2)CC1>>C#CC[C@H](NC(=O)OC(C)(C)C)C(=O)NCCCC#Cc1cccc(OC2CCN(C(=O)OC(C)(C)C)CC2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100305096A1,C=C[Mg]Br.Cc1ncc(Br)cc1[N+](=O)[O-]>>Cc1ncc(Br)c2cc[nH]c12,,C1CCOC1,,,,test
US20070287724A1,Cc1nc(Cl)c([N+](=O)[O-])c(NCC2(O)CCOCC2)c1C>>Cc1nc(Cl)c(N)c(NCC2(O)CCOCC2)c1C,[Pt],CCOC(C)=O,,,,test
US20150189880A1,CCSc1cccnc1C(=O)N(C)c1ccc(C(F)(F)C(F)(F)F)cn1.O=C(OO)c1cccc(Cl)c1>>CCS(=O)(=O)c1cccnc1C(=O)N(C)c1ccc(C(F)(F)C(F)(F)F)cn1,,ClC(Cl)Cl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20080070928A1,CC(=O)O[C@H]1C[C@H](c2cc3[nH]c(-c4ccccn4)nc3cc2Oc2ccc(S(C)(=O)=O)cc2)N(C(C)=O)C1>>CC(=O)N1C[C@@H](O)C[C@@H]1c1cc2[nH]c(-c3ccccn3)nc2cc1Oc1ccc(S(C)(=O)=O)cc1,,CO,,C[O-].[Na+],,test
US20050171130A1,CC#CCO.CC(C)(C)C(O)C(Cl)Cl.Clc1cc(Cl)ncn1>>CC#CCOc1cc(OC(C(Cl)Cl)C(C)(C)C)ncn1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20080194549A1,CC(=O)NC1(CC(=O)O)CCCC1.N[C@@H](CC(=O)O)c1ccccc1>>CC(=O)N[C@@H](CC(=O)O)c1ccccc1,,O,,CC#N,CC#N,test
US20070287725A1,CCCc1nc2c(N(Cc3ccc(OC)cc3)Cc3ccc(OC)cc3)nc(C)c(C)c2n1Cc1cc(-c2ccc(F)cc2)no1>>CCCc1nc2c(N)nc(C)c(C)c2n1Cc1cc(-c2ccc(F)cc2)no1,,O=C(O)C(F)(F)F,,,,test
US20120196848A1,CC1CN(C(=O)OC(C)(C)C)Cc2scc(-c3cccc(F)c3)c2O1>>CC1CNCc2scc(-c3cccc(F)c3)c2O1,,CCOC(C)=O,Cl,,,test
US20030149001A1,CCOC(=O)c1c(C)c2cnc(Nc3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)cn3)nc2n(C2CCCC2)c1=O.Cl>>CCOC(=O)c1c(C)c2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n(C2CCCC2)c1=O.Cl,,CCO,ClCCl,CCOCC,,test
US20090306066A1,CON.O=C1CN(Cc2ccccc2)C(=O)C12CC2>>CO/N=C1\CN(Cc2ccccc2)C(=O)C12CC2,,CO,ClCCl,Cl,CC(=O)[O-].[Na+],test
US20030013704A1,CCOC(C)=O.CS(=O)(=O)OCCCc1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1.NCCO>>CC(=O)O.O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(CCCNCCO)ccc1Cl,,CCCCO,CCOC(C)=O,,,test
US20090069340A1,CCOC(=O)C1(Cc2ccccc2)CCN(C(=O)OC(C)(C)C)CC1.Cn1c(CBr)c(Br)c(=O)n1-c1ccccc1>>CCOC(=O)C1(Cc2ccccc2)CCN(Cc2c(Br)c(=O)n(-c3ccccc3)n2C)CC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100130496A1,Clc1cc(N2CCOCC2)nc(Cl)n1.Oc1cccnc1>>Clc1cc(N2CCOCC2)nc(-c2cccnc2)n1,,CN(C)C=O,,[H-].[Na+],,test
US20100324046A1,COC(=O)c1ccc(CNS(=O)(=O)N(C)C)cc1>>CN(C)S(=O)(=O)NCc1ccc(C(=O)O)cc1,,C1CCOC1,,Cl,[K+].[OH-],test
US20100197939A1,O=C1C[C@H]([C@H](O)CO)CN1C(=O)OCc1ccccc1>>O=C[C@H]1CC(=O)N(C(=O)OCc2ccccc2)C1,,CO,O,,,test
US20050049253A1,CC(C)(C)c1ccc(N)cc1.COC(=O)c1c(CC=O)cccc1[N+](=O)[O-]>>COC(=O)c1c(CCNc2ccc(C(C)(C)C)cc2)cccc1[N+](=O)[O-],,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100239900A1,CCN(CC)CC.O=C(O)CNCC(=O)O>>CCN(CC)CC.O=C(O)CNCC(=O)O,,CS(C)=O,,,,test
US04145431,C=CCSc1ccc([N+](=O)[O-])c(N)c1>>C=CCSc1ccc(N)c(N)c1,[Fe],c1ccccc1,,O,,test
US20080280875A1,CC(C)CN.COC(=O)c1cc(OCc2ccccc2)c(CC=O)c(C(=O)OC)c1>>COC(=O)c1cc(OCc2ccccc2)c2c(c1)C(=O)N(CC(C)C)CC2,,CO,,[BH3-]C#N.[Na+],,test
US20100029636A1,CC(=O)N(C)C.CN1CCN(c2ccc(-c3cnn4c(N)c(-c5ccc(O)cc5)c(CBr)nc34)cc2)CC1>>CN1CCN(c2ccc(-c3cnn4c(N)c(-c5ccc(O)cc5)c(CC#N)nc34)cc2)CC1,,O,,Br,,test
US20150344473A1,N#Cc1cc(-c2ncnc3[nH]c(-c4ccc(N5CCOCC5)cc4)nc23)ccc1O[C@@H]1CCNC1.O=C(O)CO>>N#Cc1cc(-c2ncnc3[nH]c(-c4ccc(N5CCOCC5)cc4)nc23)ccc1O[C@@H]1CCN(C(=O)CO)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140051679A1,CC(C)C(N)c1ccccc1Cl.O=C(O)c1ccc2[nH]nc(I)c2c1>>CC(C)C(NC(=O)c1ccc2[nH]nc(I)c2c1)c1ccccc1Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20060106089A1,COc1ccc(Br)cc1S(=O)(=O)Cl.Nc1ccc(F)cc1[N+](=O)[O-]>>COc1ccc(Br)cc1S(=O)(=O)Nc1ccc(F)cc1[N+](=O)[O-],,CCOC(C)=O,c1ccncc1,,,test
US20150274720A1,CC(C)(C)[Si](C)(C)OCCC1=CCCN(Cc2ccccc2)C1.O=C(Cl)OCc1ccccc1>>CC(C)(C)[Si](C)(C)OCCC1=CCCN(C(=O)OCc2ccccc2)C1,,Cc1ccccc1,,,,test
US07235572B2,Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1[C@@H](C)O.O=S(Cl)Cl>>Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(C)Cl,,ClCCl,,,,test
US04657929,COc1ccc(CCNC(=O)C(F)(F)F)cc1N.O=C(N(CCCCCCBr)CCc1ccccc1)C(F)(F)F>>COc1ccc(CCN(CCCCCCN(CCc2ccccc2)C(=O)C(F)(F)F)C(=O)C(F)(F)F)cc1N,,CN(C)C=O,,[H-].[Na+],,test
US20130115190A1,COCC1(S(=O)(=O)NC(=O)OC(C)(C)C)CC1>>COCC1(S(N)(=O)=O)CC1,,C1COCCO1,,Cl,,test
US04002623,CN1CCN(CCCN)CC1.O=[N+]([O-])c1cccnc1Cl>>CN1CCN(CCCNc2ncccc2[N+](=O)[O-])CC1,,CCO,,,,test
US20030004351A1,CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1.NCCOCCO>>Nc1ccc(S(=O)(=O)NCCOCCO)cc1,,CO,O,Cl,O=C([O-])O.[Na+],test
US20040254376A1,CC(C)(C)OC(=O)OC(=O)[O-].CCCC1CNC(=O)C1>>CCCC1CC(=O)N(C(=O)OC(C)(C)C)C1,,ClCCl,,CCN(CC)CC,CN(C)c1ccccn1,test
US20050026973A1,CCOC(=O)C(C)(C)Oc1ccc(OCCn2c(=O)sc3cc(C(=NOC)c4ccccc4)ccc32)cc1>>CON=C(c1ccccc1)c1ccc2c(c1)sc(=O)n2CCOc1ccc(OC(C)(C)C(=O)O)cc1,,CCO,,Cl,[K+].[OH-],test
US05759443,BrCCCCCCCCC1CCCC1.CCCCCCCc1ccc(-c2ccc(O)cc2)nc1>>CCCCCCCc1ccc(-c2ccc(OCCCCCCCCC3CCCC3)cc2)nc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040082643A1,CCCC1(CC(=O)OCC)OCCc2c1[nH]c1c(C)c(C(=O)O)cc(C#N)c21>>CCCC1(CC(=O)O)OCCc2c1[nH]c1c(C)c(C(=O)O)cc(C#N)c21,,CCO,,Cl,[Na+].[OH-],test
US05872115,Brc1ccc2c(c1)C(N1CCC3(CC1)OCCO3)c1ccccc1CO2>>O=C1CCN(C2c3ccccc3COc3ccc(Br)cc32)CC1,,Cl,,CCO,,test
US20070099960A1,CC(C)(C)c1ccc(S(=O)(=O)N2c3ccccc3C[C@H]2C(=O)Cl)cc1.NCc1cccc(O)c1>>CC(C)(C)c1ccc(S(=O)(=O)N2c3ccccc3C[C@H]2C(=O)NCc2cccc(O)c2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US06586617B1,CONS(=O)(=O)c1ccc(Cl)s1.N#Cc1cc([N+](=O)[O-])ccc1Cl>>CON(c1ccc([N+](=O)[O-])cc1C#N)S(=O)(=O)c1ccc(Cl)s1,,CN(C)C=O,,O,[H-].[Na+],test
US20080076813A1,N#Cc1ccc(N2C(=O)C(CCO)=C3CCCCC32)cc1.OO>>NC(=O)c1ccc(N2C(=O)C(CCO)=C3CCCCC32)cc1,,CS(C)=O,,CCO,[Na+].[OH-],test
US20110046132A1,BrCc1ccccc1.CCOC(=O)c1cnn(-c2nc3cc(S)c(Cl)cc3n2COCCOC)c1>>CCOC(=O)c1cnn(-c2nc3cc(SCc4ccccc4)c(Cl)cc3n2COCCOC)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120101068A1,CCI.O=c1oc2cc(O)ccc2s1>>CCOc1ccc2sc(=O)oc2c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20020143020A1,CC(C)(C)OC(=O)N1CCN(C(=S)OCc2ccc(OCC(=O)c3ccccc3)cc2)CC1>>O=C(COc1ccc(COC(=S)N2CCNCC2)cc1)c1ccccc1,,CCOC(C)=O,,C1COCCO1,Cl,test
US06218397B1,CSC(SC)=C(C#N)C(N)=O.NNc1c(Cl)cc(Cl)cc1Cl>>CSc1nn(-c2c(Cl)cc(Cl)cc2Cl)c(N)c1C(N)=O,,CO,,O,,test
US20080045521A1,CC(C)(C)OC(=O)[C@@H](N)Cc1ccc(Br)nc1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)[C@H](Cc1ccc(Br)nc1)NC(=O)OCc1ccccc1,,CN(C)C=O,,,,test
US20100227889A1,CC(C)O.COCCn1c(-c2ccc(C(C)C)cc2)nc2c(C(F)(F)F)c(Cc3cccnc3S(C)(=O)=O)cc(OC)c21>>COCCn1c(-c2ccc(C(C)C)cc2)nc2c(C(F)(F)F)c(Cc3cccnc3OC(C)C)cc(OC)c21,,C1COCCO1,,[H-].[Na+],,test
US04599336,CC(C)c1ccc2nc[nH]c(=O)c2c1.COC(=O)/C=C\Cl>>COC(=O)/C=C/n1cnc2ccc(C(C)C)cc2c1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20020016368A1,COC(=O)c1cccc(CCCNC(=O)OC(C)(C)C)c1.Cl>>COC(=O)c1cccc(CCCN)c1.Cl,,CO,,,,test
US20040063946A1,CCC(N)=S.Cc1cccc(C(=O)C(Br)c2ccnc(F)c2)c1>>CCc1nc(-c2cccc(C)c2)c(-c2ccnc(F)c2)s1,,CN(C)C=O,,Br,O=C([O-])O.[Na+],test
US20060276464A1,CN(CCNS(=O)(=O)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F)C(=O)N1CCN(C(=O)OC(C)(C)C)CC1>>CN(CCNS(=O)(=O)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F)C(=O)N1CCNCC1,,CCO,,CCOC(C)=O,Cl,test
US05496935,CC(=O)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@@]1(O)F.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CC(=O)OC[C@H]1O[C@@H](n2cc(C)c(=S)[nH]c2=O)C[C@@H]1F,,c1ccncc1,,,,test
US20150336953A1,CS(=O)c1nc(N)c(Br)c(Cl)n1.c1ccc2[nH]ncc2c1>>Nc1nc(-n2ncc3ccccc32)nc(Cl)c1Br,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020147334A1,CNc1cccc(CCOc2ccc(CC(CC(=O)OC)c3nc(C(=O)OCc4ccccc4)co3)cc2)n1>>CNc1cccc(CCOc2ccc(CC(CC(=O)O)c3nc(C(=O)O)co3)cc2)n1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20100113509A1,O=[N+]([O-])c1ccc(N2C3CCC2CC3)nc1C(F)(F)F>>Nc1ccc(N2C3CCC2CC3)nc1C(F)(F)F,[Pd],,,,,test
US20120108582A1,COC(=O)C1=CCCC1.COCN(Cc1ccccc1)C[Si](C)(C)C>>COC(=O)[C@]12CCC[C@H]1CN(Cc1ccccc1)C2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070299051A1,CC(C)COC(=O)Cl.COC(=O)c1cc(C)c2c(c1)S(=O)(=O)Cc1cc(NCCN3CCCC3)cc(Cl)c1O2>>Cc1cc(C(=O)O)cc2c1Oc1c(Cl)cc(N(CCN3CCCC3)C(=O)OCC(C)C)cc1CS2(=O)=O,,ClCCl,,CCN(CC)CC,O,test
US20130244995A1,CCOC(=O)Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.O=C1C=CCC1>>CCOC(=O)Cc1ccc([C@@H]2CCC(=O)C2)cc1,,CO,ClCCl,CCN(CC)CC,,test
US20110146006A1,CC(=O)c1ccncc1.COS(=O)(=O)c1ccc(C)cc1>>CC(=O)c1cc[n+](C)cc1.Cc1ccc(S(=O)(=O)[O-])cc1,,CCO,,,,test
US20090099235A1,CC(C)(C)OC(=O)N1C(C2CC2)CC(=O)[C@@H]1C1CC1.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>O=C1CC(C2CC2)N(S(=O)(=O)c2ccc(C(F)(F)F)cc2)[C@H]1C1CC1,CN(C)c1ccncc1,C1COCCO1,,CCN(CC)CC,Cl,test
US05914402,Cc1cccc2c1=NC(=O)C1CCOC=21.Cc1ccccc1N>>Cc1ccccc1N1CCc2c1c1cccc(C)c1[nH]c2=O,,OCCOCCO,,,,test
US05102877,CC(C)(C)[Si](C)(C)OC[C@@H]1C[C@@H](OS(C)(=O)=O)CN1C(=O)OCc1ccccc1.[C-]#N>>CC(C)(C)[Si](C)(C)OC[C@@H]1C[C@H](C#N)CN1C(=O)OCc1ccccc1,,CS(C)=O,,CCOC(C)=O,O,test
US20080287458A1,COC(=O)c1ccc(Cc2c(C(=O)OC)n(-c3ccccc3)c3cc(Cl)ccc3c2=O)cc1>>COC(=O)c1c(Cc2ccc(C(=O)O)cc2)c(=O)c2ccc(Cl)cc2n1-c1ccccc1,,CO,,[Li+].[OH-],,test
US20070238765A1,COCn1ncnc1C(=O)c1c2cccc(-c3ccc(Cl)cc3Cl)c2nn1C>>Cn1nc2c(-c3ccc(Cl)cc3Cl)cccc2c1C(=O)c1ncn[nH]1,,O=C([O-])O,[Na+],CO,Cl,test
US20120309739A1,CS(=O)c1nc2oc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)c2c(=O)n1CC(F)(F)F.NCCO>>CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4nc(NCCO)n(CC(F)(F)F)c(=O)c4c3-c3ccccc3)cc2)CCC1,,C1CCOC1,,,,test
US20050014812A1,CCOC(=O)CCCOc1ccc2nc(OCC)n(Cc3ccc(Cl)cc3Cl)c2c1>>CCOc1nc2ccc(OCCCC(=O)O)cc2n1Cc1ccc(Cl)cc1Cl,,CCO,,Cl,[Na+].[OH-],test
US04677100,CC(C)(C)OC(=O)C(C)(C)O/N=C(\C(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CCl)CS[C@H]12)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)OC(=O)C(C)(C)O/N=C(\C(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CCl)CS(=O)[C@H]12)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20020147334A1,CCOC(=O)/C=C(/Cc1ccc(OCc2ccccc2)cc1)c1ccccn1>>CCOC(=O)CC(Cc1ccc(O)cc1)c1ccccn1,[Pd],CC(C)O,CCOC(C)=O,,,test
US04624962,C=C(CCc1ccccc1)C(=O)OCC.CN>>CCOC(=O)C(CCc1ccccc1)CNC,,CCO,,,,test
US20050096380A1,CC(=O)OC(C)=O.COc1c(C(C)O)cc2c(c1Br)C(C)(C)CCC2>>COc1c(C(C)OC(C)=O)cc2c(c1Br)C(C)(C)CCC2,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20060068322A1,C=Cc1ccc(OC(C)OCC)c(OC)c1.O=C1C=CC(=O)N1c1ccc(O)cc1>>C=Cc1ccc(OC(C)OCC)c(OC)c1.O=C1C=CC(=O)N1c1ccc(O)cc1,,C1CCOC1,CCCCCC,,,test
US04489089,O=C1c2ccccc2C(=O)N1CC=CCCl.c1c[nH]cn1>>O=C1c2ccccc2C(=O)N1CC=CCn1ccnc1,,CN(C)C=O,,[Na],,test
US20090258851A1,CC(=O)OCc1nc(-c2ccc(C(C)(c3ccc(OCc4ccccn4)cn3)C(C)C)cc2)no1>>CC(C)C(C)(c1ccc(-c2noc(CO)n2)cc1)c1ccc(OCc2ccccn2)cn1,,CO,O,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US05430032,O=C1c2ccc(Cl)cc2OCc2cccnc21>>OC1c2ccc(Cl)cc2OCc2cccnc21,,CCO,,[BH4-].[Na+],,test
US20100298388A1,COS(=O)(=O)OC.NC(=NO)c1c(F)ccc(OCc2nc3cc(Cl)ccc3s2)c1F>>CON=C(N)c1c(F)ccc(OCc2nc3cc(Cl)ccc3s2)c1F,,C1CCOC1,,O,[Na+].[OH-],test
US05215982,CCOC(OCC)C(C)n1ncc(C(=O)O)c1N>>Cc1c[nH]c2ccnn12,,C1CCOC1,,Cl,O=C([O-])[O-].[K+].[K+],test
US20110266526A1,BrBr.c1ccc2c(c1)c1cccc3sc4cccc2c4c31>>Brc1ccc2sc3cccc4c5ccccc5c1c2c34,,ClC(Cl)Cl,,,,test
US20160194284A1,CC(C)(C)OC(=O)NCCc1c(C(=O)O)[nH]c2ccc(Cl)cc12.CCN=C=NCCCN(C)C.CCOC(C)=O.CN1CCCC1=O.On1nnc2ccccc21>>CC(C)(C)OC(=O)NCCc1c(C(=O)NCCc2ccc(N3CCCCC3)cc2)[nH]c2ccc(Cl)cc12,,CCOC(C)=O,O,CCN(C(C)C)C(C)C,,test
US20100069388A1,CN(Cc1ccccc1)C[C@@H](CCc1ccccc1)Nc1cnc(/C=C/C(=O)NOC2CCCCO2)cn1>>CN(Cc1ccccc1)C[C@@H](CCc1ccccc1)Nc1cnc(/C=C/C(=O)NO)cn1,,CCO,,CCOC(C)=O,Cl,test
US20090298823A1,Clc1nc(NC2CCC2)c2c(Cl)c[nH]c2n1.Nc1ccc2cn[nH]c2c1>>Clc1c[nH]c2nc(Nc3ccc4cn[nH]c4c3)nc(NC3CCC3)c12,,CCCCO,,C[Si](C)(C)Cl,,test
US05700809,CC(C)(C)OC(=O)N1CCc2cc(-c3ccc(Cl)cc3)ccc2C1>>Clc1ccc(-c2ccc3c(c2)CCNC3)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06756378B2,COC(=O)c1ccc(OC[C@@H]2C[C@@H](O)CN2C(=O)OC(C)(C)C)cc1.ClC(Cl)(Cl)Cl>>COC(=O)c1ccc(OC[C@@H]2C[C@H](Cl)CN2C(=O)OC(C)(C)C)cc1,,ClC(Cl)Cl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20160176864A1,BrC1CCOCC1.O=CCC1CC1>>OC(CC1CC1)C1CCOCC1,,C1CCOC1,,II,[Mg],test
US20130018043A1,Cc1cn(-c2ccccc2Cl)c2cc(Cl)ccc2c1=O.O=C1CCC(=O)N1Br>>O=c1c(CBr)cn(-c2ccccc2Cl)c2cc(Cl)ccc12,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20150232445A1,C[C@H]1CCc2c(ccc(-c3ncc(C4CCN(C(=O)OC(C)(C)C)CC4)n3COCC[Si](C)(C)C)c2OC2CCC2)N1C(=O)C1CC1>>C[C@H]1CCc2c(ccc(-c3ncc(C4CCNCC4)[nH]3)c2OC2CCC2)N1C(=O)C1CC1,,C1CCOC1,ClCCl,Cl,,test
US05034392,C#CCBr.O=C1CSCN1>>C#CCN1CSCC1=O,,CN(C)C=O,Cc1ccccc1,[H-].[Na+],,test
US20130183269A1,BrCc1ccccc1.O=C1CC2(C1)CC(C(=O)O)C2>>O=C1CC2(C1)CC(C(=O)OCc1ccccc1)C2,,CC#N,ClC(Cl)Cl,CCN(C(C)C)C(C)C,,test
US20130102776A1,COc1ccc2c(c1/C=C\CC1CCN(C(=O)OC(C)(C)C)CC1)OCC2=O.O=Cc1n[nH]c2ccccc12>>COc1ccc2c(c1/C=C\CC1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccccc13)C2=O,C1CCNCC1,CO,,,,test
US06114332,COC(=O)c1cccc2cc3ccc(C(F)(F)F)cc3nc12>>O=C(O)c1cccc2cc3ccc(C(F)(F)F)cc3nc12,,CO,O,,,test
US04950667,Nc1ccccc1Nc1ccccc1.O=C(Cl)CCl>>O=C(CCl)Nc1ccccc1Nc1ccccc1,,ClC(Cl)Cl,O,CCN(CC)CC,,test
US20110230458A1,BrC1CCCCC1.O=Cc1ccc(O)c(Br)c1>>O=Cc1ccc(OC2CCCCC2)c(Br)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06015774,CI.COc1cc(-c2ncc(C(F)(F)F)[nH]c2=O)c(F)cc1Cl>>COc1cc(-c2ncc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070060607A1,CCOC(=O)c1cnc(N)c2c(COc3cc(OCc4ccc(Cl)cc4)ccc3Cl)csc12.NCCO>>Nc1ncc(C(=O)NCCO)c2scc(COc3cc(OCc4ccc(Cl)cc4)ccc3Cl)c12,,CS(C)=O,,,,test
US04082757,COC(=O)C1=C(O)c2ccsc2S(=O)(=O)C1.Nc1nccs1>>O=C(Nc1nccs1)C1=C(O)c2ccsc2S(=O)(=O)C1,,Cc1ccccc1C,,,,test
US05767131,CCCCCC(=O)CC(=O)OCCC#N.O=Cc1ccc([N+](=O)[O-])cc1>>CCCCCC(=O)C(=Cc1ccc([N+](=O)[O-])cc1)C(=O)OCCC#N,,CC(C)O,,C1CCNCC1,CC(=O)O,test
US20110306604A1,O=C1Nc2ncccc2[C@@]12Cc1cc3cc(CO)cnc3cc1C2.O=S(Cl)Cl>>O=C1Nc2ncccc2[C@@]12Cc1cc3cc(CCl)cnc3cc1C2,,ClCCl,,,,test
US05854268,CC(C)(C)OC(=O)N1CC[C@@H](CS(=O)(=O)Cc2ccc(F)cc2)C1>>O=S(=O)(Cc1ccc(F)cc1)C[C@@H]1CCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150344437A1,COC(=O)C(C)C(=O)c1ccc(S(=O)(=O)N(C)C)cc1.NN>>Cc1c(-c2ccc(S(=O)(=O)N(C)C)cc2)n[nH]c1O,,CCO,,O,,test
US20080234255A1,CC1CCCC1N1CCC(=O)N(C)c2cnc(Cl)nc21.COc1cc(C(=O)O)ccc1N>>COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1C)CCC(=O)N2C,Cl,O,,CCO,,test
US20120264735A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCC(F)CNCc1ccccc1>>CC(C)(C)OC(=O)NCC(F)CO,[Pd],C1CCOC1,CO,O=C[O-].[NH4+],,test
US04035376,CC(Cl)c1ccc(C(=O)Cl)cc1.c1ccsc1>>CC(Cl)c1ccc(C(=O)c2cccs2)cc1,,ClCCl,,Cl,,test
US05132424,NO.O=C(Cn1c2c(c(=O)n3nc(-c4ccccc4)cc13)CN(C1CCCCC1)C2=O)c1ccccc1>>O=C1c2c(c(=O)n3nc(-c4ccccc4)cc3n2CC(=NO)c2ccccc2)CN1C1CCCCC1,,CCO,,Cl,c1ccncc1,test
US04508562,O=C(OO)c1cccc(Cl)c1.[O-][n+]1cc(Cl)ccc1SCc1c(Cl)cccc1Cl>>O=S(Cc1c(Cl)cccc1Cl)c1ccc(Cl)c[n+]1[O-],,ClC(Cl)Cl,,,,test
US05886015,CNN.O=C(C=Cc1ccccc1)c1cccc(O)c1>>CN1N=C(c2cccc(O)c2)CC1c1ccccc1,,CCO,,,,test
US20090270635A1,O=C1CCC(=O)N1Br.c1ccc(N2CCCC2)cc1>>Brc1ccc(N2CCCC2)cc1,,C1CCOC1,,[Na+].[OH-],,test
US20020198195A1,II.O=C(O)c1cccc(O)c1>>O=C(O)c1ccc(I)c(O)c1,,O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20090005558A1,CC(C)(C)OC(=O)N1CC2CNCC(C1)O2.N#Cc1ccc(S(=O)(=O)NCCBr)cc1>>CC(C)(C)OC(=O)N1CC2CN(CCNS(=O)(=O)c3ccc(C#N)cc3)CC(C1)O2,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US07423059B2,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1ccc(-c2ccc(-c3ccccc3)[nH]2)cc1>>CC(C)(C)OC(=O)n1c(-c2ccccc2)ccc1-c1ccccc1,CN(C)c1ccncc1,CC#N,,,,test
US20130072470A1,Cc1ccc(S(=O)(=O)n2ccc3c2ncc2nnc([C@H]4CC5(C[C@H]4C)OCCO5)n23)cc1>>C[C@@H]1CC2(C[C@@H]1c1nnc3cnc4[nH]ccc4n13)OCCO2,,C1COCCO1,,O,[Na+].[OH-],test
US20090170907A1,CC(C)(C)OC(=O)N1CCC(c2nc(CN(CC(F)(F)F)c3ccc(C#N)c(C(F)(F)F)c3)no2)CC1>>N#Cc1ccc(N(Cc2noc(C3CCNCC3)n2)CC(F)(F)F)cc1C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160137639A1,Cc1ccc(NC(=O)C[C@H](CCCOCc2ccccc2)c2noc(-c3cc(CC(C)C)no3)c2C2CC2)c(Cl)c1>>Cc1ccc(NC(=O)C[C@H](CCCO)c2noc(-c3cc(CC(C)C)no3)c2C2CC2)c(Cl)c1,,ClCCl,,BrB(Br)Br,,test
US20110263626A1,O=Cc1ccc(F)cc1.Oc1ccc(Br)cc1Cl>>O=Cc1ccc(Oc2ccc(Br)cc2Cl)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100137313A1,COC(=O)c1cc(-c2cnc(Nc3cc(C)cc(OC)c3)nc2-n2ccc(C(F)(F)F)n2)cn(C)c1=O>>COc1cc(C)cc(Nc2ncc(-c3cc(C(=O)O)c(=O)n(C)c3)c(-n3ccc(C(F)(F)F)n3)n2)c1,,C1CCOC1,,O,[Na+].[OH-],test
US20070072853A1,CC(=O)Nc1ccc(F)c([N+](=O)[O-])c1.CCI>>CCN(C(C)=O)c1ccc(F)c([N+](=O)[O-])c1,,C1CCOC1,,[H-].[Na+],,test
US05358966,CC(C)(C)NNC(=O)c1ccc(Cl)cc1.O=C(Cl)c1ccccc1>>CC(C)(C)N(NC(=O)c1ccc(Cl)cc1)C(=O)c1ccccc1,,O,,ClCCl,[Na+].[OH-],test
US05102771,C1=COCCC1.C=C(C)C(=O)O>>C=C(C)C(=O)OC1CCCCO1,,ClCCl,,,,test
US20070173521A1,C[Si](C)(C)CCOC(=O)c1ccc2c(c1)C(=O)CC2>>C[Si](C)(C)CCOC(=O)c1ccc2c(c1)[C@@H](O)CC2,,C1CCOC1,Cc1ccccc1,,,test
US20080207654A1,CCCOc1ccc(-n2c(C)nc(CCC)c(Cc3ccc(-c4ccccc4C#N)cc3)c2=O)cc1.O=C([O-])O.[NH3+]O>>CCCOc1ccc(-n2c(C)nc(CCC)c(Cc3ccc(-c4ccccc4-c4noc(=O)[nH]4)cc3)c2=O)cc1,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US20140221332A1,NC(=NO)c1ccc(C#Cc2cccc(F)c2)cc1.O=C(OC(=O)C(Cl)(Cl)Cl)C(Cl)(Cl)Cl>>Fc1cccc(C#Cc2ccc(-c3noc(C(Cl)(Cl)Cl)n3)cc2)c1,,Cc1ccccc1,O,,,test
US04122083,CC(=O)N1CCc2c(sc3nc4ccccc4n23)C1>>c1ccc2c(c1)nc1sc3c(n12)CCNC3,,CCO,,[Na+].[OH-],,test
US20090253684A1,COc1cc(C(=O)O)cc([N+](=O)[O-])c1>>COc1cc(N)cc(C(=O)O)c1,,CCO,,,,test
US20030060470A1,CC(C)(C)OC(=O)NCc1ccccc1B(O)O.COC(=O)c1nccnc1Br>>COC(=O)c1nccnc1-c1ccccc1CNC(=O)OC(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,ClCCl,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20040014968A1,COC(=O)C(CC1CCCC1)c1ccc(S(C)(=O)=O)c([N+](=O)[O-])c1>>COC(=O)C(CC1CCCC1)c1ccc(S(C)(=O)=O)c(N)c1,[Zn],CO,O,[Cl-].[NH4+],,test
US04592866,CN1CC(CCCl)Oc2cc3ccccc3nc2C1=O.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CN1CC(CCCl)Oc2cc3ccccc3nc2C1=S,,CC#N,Cc1ccccc1,,,test
US20110230478A1,CCCN.N#Cc1cnc(Nc2ccccc2)nc1Cl>>CCCNc1nc(Nc2ccccc2)ncc1C#N,,CC#N,,CCN(CC)CC,O,test
US04713381,Cc1nc2sccn2c1C(=O)NNC(=O)CCl>>Cc1nc2sccn2c1C1=NNC(=O)CO1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090137588A1,CC(C)(C)OC(=O)N1CCCC(Nc2cc(Nc3ccc(Oc4ccccc4)cc3)ncn2)C1>>c1ccc(Oc2ccc(Nc3cc(NC4CCCNC4)ncn3)cc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05985886,CCOC(=O)C(Cc1ccc2c(c1)OCO2)C(=O)O>>COc1ccc2c(c1)OCO2,,c1ccccc1,,C1CCNCC1,CC(=O)O,test
US20100331338A1,CCOC(=O)c1ccc(C)s1.O=S(=O)(O)Cl>>CCOC(=O)c1cc(S(=O)(=O)Cl)c(C)s1,,ClCCl,,,,test
US20050176689A1,C=Cc1cc(C#Cc2ccc(CC(=O)OC)cc2)cc2c1C(N(C)C1CC1)CCC2(C)C>>C=Cc1cc(C#Cc2ccc(CC(=O)O)cc2)cc2c1C(N(C)C1CC1)CCC2(C)C,,C1CCOC1,CO,[Li+].[OH-],,test
US05840732,ClCCCCBr.O=c1[nH]c(=O)n2c(c1-c1ccccc1)SCCC2>>O=c1c(-c2ccccc2)c2n(c(=O)n1CCCCCl)CCCS2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110015202A1,CCOC(=O)Cn1ccc(-n2cc(C#Cc3cccc(C)c3)nc2C)cc1=O.CNC>>Cc1cccc(C#Cc2cn(-c3ccn(CC(=O)N(C)C)c(=O)c3)c(C)n2)c1,,CCO,,,,test
US20120270879A1,O=CNC(c1ccc(F)cc1)c1cccc(Br)n1>>Fc1ccc(-c2ncn3c(Br)cccc23)cc1,,O=P(Cl)(Cl)Cl,,,,test
US20130065861A1,CCCCCCCCCCCCOC[C@H](CSC[C@@H](C(=O)NCCOCCOCCOCCP(=O)(OCC)OCC)N(C)C(=O)OC1c2ccccc2-c2ccccc21)NC(=O)CCCCCCCCCCC>>CCCCCCCCCCCCOC[C@H](CSC[C@H](N)C(=O)NCCOCCOCCOCCP(=O)(OCC)OCC)NC(=O)CCCCCCCCCCC,,C1CCOC1,CN(C)C=O,C1CCNCC1,,test
US20160016966A1,CI.COc1cc[nH]c(=O)c1>>COc1ccn(C)c(=O)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04435397,BrCC1CO1.O=c1ccc2ccc(O)cc2o1>>O=c1ccc2ccc(OCC3CO3)cc2o1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100168094A1,CCOC(=O)N1CC(C(=O)Nc2cc(OC(=O)OC)c(C3CCCC3)cc2C2=CCN(C(=O)OC(C)(C)C)CC2)Oc2ccc(C#N)cc21>>N#Cc1ccc2c(c1)NCC(C(=O)Nc1cc(O)c(C3CCCC3)cc1C1=CCNCC1)O2,,CO,O,Cl,[Na+].[OH-],test
US20040097561A1,CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccccc1C(=O)O.Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1.c1ccncc1>>CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20110251190A1,C[Mg]Cl.O=c1c2cc(Cl)ncc2oc2c(F)cc(Br)cc12>>CC1(O)c2cc(Cl)ncc2Oc2c(F)cc(Br)cc21,,C1CCOC1,C1CCOC1,,,test
US20080275060A1,CC(C)C[C@@H](CN(OCc1ccccc1)C(=O)OC(C)(C)C)C(=O)O.COc1ccc(N2CCNCC2)cc1>>COc1ccc(N2CCN(C(=O)[C@@H](CC(C)C)CN(OCc3ccccc3)C(=O)OC(C)(C)C)CC2)cc1,,CCOCC,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120225854A1,C1COCCN1.CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)CC2C=O)cc1)C(F)(F)F>>CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)CC2CN2CCOCC2)cc1)C(F)(F)F,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04963566,NO.O=C1CCN2C(=O)OCc3cccc1c32>>O=C1OCc2cccc3c2N1CCC3=NO,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20150183768A1,COC(CC(=N)NO)OC.O=C(O)c1ccc(F)cn1>>COC(Cc1noc(-c2ccc(F)cn2)n1)OC,,CN(C)C=O,,O,O=C(n1ccnc1)n1ccnc1,test
US20030195232A1,CCOC(=O)CCc1ccncc1OCOC>>COCOc1cnccc1CCCO,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20030069297A1,Cc1cc(C(=O)NCCn2ccnn2)c(C=O)[nH]1.O=C1Cc2c(cccc2-c2cccc(C(F)(F)F)c2)N1>>Cc1cc(C(=O)NCCn2ccnn2)c(C=C2C(=O)Nc3cccc(-c4cccc(C(F)(F)F)c4)c32)[nH]1,C1CCNCC1,CCO,,,,test
US20040087798A1,Nc1cccc(-c2cncnc2)c1.O=C(O)C1=Cc2cc(F)ccc2OCC1>>O=C(Nc1cccc(-c2cncnc2)c1)C1=Cc2cc(F)ccc2OCC1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20150133480A1,CCc1ncc(CCl)c(N)n1.Cc1ncsc1CCF.Cl>>CC1=C(CCF)SCN1Cc1cnc(C)nc1N.Cl.[Cl-],,CC(C)O,,CS(C)=O,,test
US20110021537A1,CC(C)(C)OC(=O)N1CCN(C(=O)Oc2ccccc2)CC1>>O=C(Oc1ccccc1)N1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100305336A1,O=C(Cl)CCCl.O=C(c1ccccc1)c1ccc(OCCO)cc1>>O=C(CCCl)OCCOc1ccc(C(=O)c2ccccc2)cc1,,CCC(C)=O,,CCN(CC)CC,,test
US20100016287A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1c(O)ccc2c1CCNCC2>>Cc1c(O)ccc2c1CCN(C(=O)OC(C)(C)C)CC2,,C1CCOC1,,Br,CCN(CC)CC,test
US20120101093A1,CN.O=[N+]([O-])c1ccc(-c2cccc(C(F)(F)F)c2)cc1F>>CNc1cc(-c2cccc(C(F)(F)F)c2)ccc1[N+](=O)[O-],,C1CCOC1,,,,test
US20050165087A1,NC(=O)c1cc(Br)sc1NC(=O)NC(=O)C(Cl)(Cl)Cl>>NC(=O)Nc1sc(Br)cc1C(N)=O,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCCC1.Oc1ccc2cc(F)cnc2c1>>COc1cc2c(Oc3ccc4cc(F)cnc4c3)ncnc2cc1OCCCN1CCCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030236287A1,CO.Cc1cc([N+](=O)[O-])c(Cl)cc1OCC(F)(F)F>>COc1cc(OCC(F)(F)F)c(C)cc1[N+](=O)[O-],,CN(C)C=O,O,[H-].[Na+],,test
US04146630,CC(C)(C)C(=O)Cl.OC(COc1cccc2nc[nH]c12)CN1CCC(COc2ccccc2)CC1>>CC(C)(C)C(=O)OC(COc1cccc2nc[nH]c12)CN1CCC(COc2ccccc2)CC1.Cl,,ClC(Cl)Cl,,c1ccncc1,,test
US20110118245A1,COCCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)c2cc1OC.Cl>>COCCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)c2cc1OC.Cl,,CO,ClCCl,CCOCC,,test
US20070208055A1,CCCOC(=O)C(C(=O)OCC)(C(=O)[C@H](C[C@H](Cc1ccc(OC)c(OCCCOC)c1)C(C)C)NC(=O)OC(C)(C)C)[C@@H](C(=O)OCC)C(C)C>>COCCCOc1cc(C[C@@H](C[C@H](NC(=O)OC(C)(C)C)C(=O)C[C@H](C(=O)O)C(C)C)C(C)C)ccc1OC,,CCO,,[Na+].[OH-],,test
US04367233,O=C(O)C(Br)c1ccc(Cl)cc1.Sc1nc2ccc(Cl)nc2s1>>O=C(O)C(Sc1nc2ccc(Cl)nc2s1)c1ccc(Cl)cc1,,CCN(CC)CC,,ClCCl,,test
US20040242928A1,Cc1cc(COc2ccc(S(=O)(=O)C=CC=C3CCN(C(=O)O)CC3)cc2)c2ccccc2n1>>Cc1cc(COc2ccc(S(=O)(=O)C=CC=C3CCNCC3)cc2)c2ccccc2n1,,CO,,C1COCCO1,Cl,test
US20120245153A1,O=C1NC2(CCCC2)C(=O)N1c1ccc([N+](=O)[O-])cc1Cl>>Nc1ccc(N2C(=O)NC3(CCCC3)C2=O)c(Cl)c1,,CO,,,,test
US20050288367A1,CNC(=O)C(C)Oc1ccc(O)cc1.N#Cc1ccc(CBr)cc1>>CNC(=O)C(C)Oc1ccc(OCc2ccc(C#N)cc2)cc1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US03931218,CCNCCN.Cc1ccc(S(=O)(=O)Cl)cc1>>CCNCCNS(=O)(=O)c1ccc(C)cc1,,c1ccncc1,,,,test
US20150011600A1,Cc1ccc2[nH]c(=O)[nH]c2c1.O=P(Cl)(Cl)Cl>>Cc1ccc2[nH]c(Cl)nc2c1,,ClC(Cl)Cl,,,,test
US03974140,C[Si](C)(C)Cl.S=C1NCCN1>>C[Si](C)(C)N1CCNC1=S,,C1CCOC1,,CCN(CC)CC,,test
US20160237090A1,CC(C)(C)OC(=O)N1CCn2nnc(-c3ccc(F)cc3)c2C1>>Fc1ccc(-c2nnn3c2CNCC3)cc1,,CO,Cl,,,test
US20090029980A1,CC(C)(C)OC(=O)N1C=CCC1.COc1ccc(C(Cl)=NO)cn1>>COc1ccc(C2=NO[C@H]3CN(C(=O)OC(C)(C)C)C[C@@H]23)cn1,,CCOC(C)=O,,O=C([O-])O.[Na+],,test
US20040229864A1,O=S([O-])OO.c1ccc(SC2CC2)cc1>>O=S(=O)(c1ccccc1)C1CC1,,CO,,O,,test
US20010044415A1,C[C@H](N)C(=O)N[C@H](C=O)CC(=NNC(N)=O)OC(C)(C)C.O=C(O)c1cc2ccccc2n1Cc1ccccc1>>C[C@H](NC(=O)c1cc2ccccc2n1Cc1ccccc1)C(=O)N[C@H](C=O)CC(=NNC(N)=O)OC(C)(C)C,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN=C=NCCCN(C)C,,test
US20110201593A1,Nc1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1NC1CCN(Cc2ccccc2)CC1.O=C(Cl)CCl>>O=C(CCl)Nc1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1NC1CCN(Cc2ccccc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20100204196A1,COc1cc2c(cc1N)N(C(=O)CN(C)C)CC2>>COc1cc2c(cc1N)N(CCN(C)C)CC2,,CCOC(C)=O,CCOCC,C1CCOC1,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050148590A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.CC1(C)CCCc2ccc(Br)cc21>>CC(=O)c1ccc2c(c1)C(C)(C)CCC2,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,,Cl,,test
US20100041658A1,CC(C)(C)OC(=O)NCC(=O)O.CCc1ccc(Oc2ccc(C(C)=O)cc2F)c(O)c1>>CCc1ccc(Oc2ccc(C(C)=O)cc2F)c(OC(=O)CNC(=O)OC(C)(C)C)c1,,C1CCOC1,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20140323418A1,CNC.CSc1ncc(C(N)=O)c(Nc2cccc(-n3nccn3)c2)n1>>CN(C)c1ncc(C(N)=O)c(Nc2cccc(-n3nccn3)c2)n1,,CCOC(C)=O,CN(C)C=O,O=C(OO)c1cccc(Cl)c1,,test
US20090181963A1,O=C(Cl)c1ccncc1.Oc1cccc(-c2nc(N3CCOCC3)c3nnn(CCN4CCNCC4)c3n2)c1>>O=C(c1ccncc1)N1CCN(CCn2nnc3c(N4CCOCC4)nc(-c4cccc(O)c4)nc32)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20050004014A1,CCCCC1(OC)CCN(c2ccc(C(=O)OCC)cc2)CC1.NN>>CCCCC1(OC)CCN(c2ccc(C(=O)NN)cc2)CC1,,C1CCOC1,CCO,O,,test
US20150025065A1,CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2[C@H](Oc3nc4cc(Cl)c(I)nc4n3COCC[Si](C)(C)C)CO[C@H]12.CC1(C)OB(c2ccc([C@@H]3CC[C@@H](O)CC3)cc2)OC1(C)C>>CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2[C@H](Oc3nc4cc(Cl)c(-c5ccc([C@@H]6CC[C@@H](O)CC6)cc5)nc4n3COCC[Si](C)(C)C)CO[C@H]12,,CCO,O,O=C([O-])[O-].[K+].[K+],,test
US20150126490A1,N[C@H](CO)c1cc(F)cc(I)c1.O=C(Cl)OCC1c2ccccc2-c2ccccc21>>O=C(N[C@H](CO)c1cc(F)cc(I)c1)OCC1c2ccccc2-c2ccccc21,,CCOC(C)=O,O,C1CCOC1,O=C([O-])O.[Na+],test
US20130072487A1,CCOC(=O)c1c(O)[nH]c(=O)n(Cc2ccccc2)c1=O.NCC(=O)O>>O=C(O)CNC(=O)c1c(O)[nH]c(=O)n(Cc2ccccc2)c1=O,,CCO,CCOC(C)=O,C1CCC2=NCCCN2CC1,,test
US20100240638A1,C=C[C@@H]1C[C@]1(N)C(=O)NS(=O)(=O)c1ccccc1NC(=O)CCCCCCC(=O)OC.COc1ccc2c(O[C@@H]3C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C3)cc(-c3ccccc3)nc2c1>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H](Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)CN1C(=O)OC(C)(C)C)C(=O)NS(=O)(=O)c1ccccc1NC(=O)CCCCCCC(=O)OC,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120046287A1,CC1C(=O)N(S)c2ccc(CN3N=C(c4ccc(Cl)cc4)COC3=O)cc21>>O=C1Cc2cc(CN3N=C(c4ccc(Cl)cc4)COC3=O)ccc2N1,[Zn],CC(=O)O,,,,test
US20160194290A1,C=CC(C(C)C)C(C)(N=C=O)c1ccc(CCC(C)(C)C)c(Cl)c1.CCOC(=O)CCN>>C=CC(C(C)C)C(C)(NC(=O)NCCC(=O)OCC)c1ccc(CCC(C)(C)C)c(Cl)c1,,C1COCCO1,,CCN(CC)CC,Cl,test
US20060100230A1,CC(C)c1c[nH]c2ccc(Cl)nc12.OB(O)c1ccc(C(F)(F)F)cc1>>CC(C)c1c[nH]c2ccc(-c3ccc(C(F)(F)F)cc3)nc12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US07812047B2,C=C[Sn](CCCC)(CCCC)CCCC.CCOC(=O)c1cccc2cccc(Br)c12>>C=Cc1cccc2cccc(C(=O)OCC)c12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,[F-].[K+],,test
US05597820,CC(Cl)C(=O)Cl.COC(=O)c1ccc(N)c(O)c1>>COC(=O)c1ccc2c(c1)OC(C)C(=O)N2,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110112080A1,CC(C)(C)OC(=O)NC(CO)c1ccc(I)cc1.COC(C)(C)OC>>CC(C)(C)OC(=O)N1C(c2ccc(I)cc2)COC1(C)C,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20090286777A1,C=CCI.COC(=O)C(C)C[C@H]1[C@H](c2ccc(F)cc2)[C@@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CN1C(=O)OC(C)(C)C>>C=CCC(C)(C[C@H]1[C@H](c2ccc(F)cc2)[C@@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CN1C(=O)OC(C)(C)C)C(=O)OC,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20040053908A1,COc1cc2nccc(Oc3ccc(NC(=O)Oc4ccccc4)c(F)c3)c2cc1OC.Nc1nccs1>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4nccs4)c(F)c3)c2cc1OC,,CO,CS(C)=O,CCOC(C)=O,O,test
US20140329812A1,C#Cc1ccc(CO)cc1.CC(C)c1cc(N=[N+]=[N-])c(OCc2ccccc2)cc1OCc1ccccc1>>CC(C)c1cc(-n2nncc2-c2ccc(CO)cc2)c(OCc2ccccc2)cc1OCc1ccccc1,,CN(C)C=O,,CCOC(C)=O,O,test
US05659059,FC(F)(F)Oc1ccc(-c2ccc(C3CC[SiH](Cl)CC3)cc2)cc1.FCCCCBr>>FCCCC[Si@@H]1CC[C@@H](c2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)CC1,,C1CCOC1,,[Mg],,test
US20080267948A1,CS(C)=O.O=c1oc2c(O)c(O)cc3c(=O)oc4c(O)c(O)cc1c4c23>>O=C1C=C2CC3(O)COc4c(ccc(O)c4O)C3=C2C=C1O,,CS(C)=O,,,,test
US20130085157A1,Cc1nnc2sc(Br)c(-c3ccccc3)n12.Fc1cccc(Cl)c1CS>>Cc1nnc2sc(SCc3c(F)cccc3Cl)c(-c3ccccc3)n12,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05332741,COc1ccccc1N1CCNCC1.c1cc2c(c(OCC3CO3)c1)SCCC2>>COc1ccccc1N1CCN(CC(O)COc2cccc3c2SCCC3)CC1,,C1CCOC1,,,,test
US20020037888A1,CCC1(c2cccc(OCc3ccccc3)c2)CCCCN(CCO)C1=O>>CCC1(c2cccc(O)c2)CCCCN(CCO)C1=O,[Pd],CO,,,,test
US20070208166A1,CC(C)(C)OC(=O)N1CCNCC1.O=C(CCl)Nc1ccccn1>>CC(C)(C)OC(=O)N1CCN(CC(=O)Nc2ccccn2)CC1,,CC(=O)N(C)C,O,,,test
US05981546,C#C[C@H](CC(=O)OCC)NC(C)=O>>C#C[C@H](CC(=O)O)NC(C)=O,,CCO,,[Na+].[OH-],,test
US20040259859A1,COc1ccc(CN2CC3CCC(C2)C3=O)cc1.COc1cccc([Mg]Br)c1>>COc1ccc(CN2CC3CCC(C2)C3(O)c2cccc(OC)c2)cc1,,C1CCOC1,,,,test
US20090030015A1,COC(=O)Cc1ccc(-c2ccccc2NC(=O)c2cccc(-c3ccc(OC)cc3OC)c2)s1>>COc1ccc(-c2cccc(C(=O)Nc3ccccc3-c3ccc(CC(=O)O)s3)c2)c(OC)c1,,CC#N,,[Li+].[OH-],,test
US05162308,BrCc1ccccc1.N#Cc1c(Br)[nH]c(Br)c1Br>>N#Cc1c(Br)c(Br)n(Cc2ccccc2)c1Br,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20100069381A1,O=C(CCc1cccc(C(F)(F)F)c1)NNC(=O)c1ccc2ncsc2c1>>FC(F)(F)c1cccc(CCc2nnc(-c3ccc4ncsc4c3)o2)c1,,CCOC(C)=O,c1ccncc1,Cc1ccc(S(=O)(=O)Cl)cc1,,test
US20150191461A1,Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cn[nH]c2)c1.c1ccc(C2CO2)cc1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnn(CC(O)c3ccccc3)c2)c1,,O,,CN(C)C=O,[H-].[Na+],test
US07884114B2,CCCCc1cc(OC2CCN(CCCCN)CC2)c2ncccc2c1.CCS(=O)(=O)Cl>>CCCCc1cc(OC2CCN(CCCCNS(=O)(=O)CC)CC2)c2ncccc2c1,,ClCCl,,CCN(CC)CC,,test
US20040186140A1,N=CN.Nc1ncccc1C(=O)O>>Oc1ncnc2ncccc12,,CCOCCO,,CC(=O)O,,test
US20120302610A1,CCOC(=O)CCNC(=O)c1ccc(-c2cc(Cl)cc(C=O)c2)cn1.Nc1ccc(-c2ccc(F)cc2)cc1>>CCOC(=O)CCNC(=O)c1ccc(-c2cc(Cl)cc(CNc3ccc(-c4ccc(F)cc4)cc3)c2)cn1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20050215578A1,COc1ccc(CSc2nsc(Cl)n2)cc1.OCc1ccccc1>>COc1ccc(CSc2nsc(OCc3ccccc3)n2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20040072690A1,CCCCCCC(=O)NCCOc1ccc(CC(OCC)C(=O)OCC)cc1>>CCCCCCCNCCOc1ccc(CC(OCC)C(=O)OCC)cc1,,C1CCOC1,,CCCCO,,test
US04469868,Cc1nc(N2CC2C)c2c(n1)c(C)nn2C>>CC1=Nc2c(C)nn(C)c2C2=NC(C)CN12,,CC(C)=O,,[I-].[Na+],,test
US05753664,COc1nc(SC)nc2c1ccn2Cc1ccc(C(=O)c2ccc(Cl)cc2)cc1>>CSc1nc2c(ccn2Cc2ccc(C(=O)c3ccc(Cl)cc3)cc2)c(=O)[nH]1,,C1COCCO1,,Cl,,test
US20030176430A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)[Si](C)(C)O[C@@H]1C[C@H]2CNCC(C(c3ccccc3)c3ccccc3)N2C1>>CC(C)(C)OC(=O)N1CC(C(c2ccccc2)c2ccccc2)N2C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]2C1,,ClCCl,,CCN(CC)CC,,test
US20090227566A1,COCOc1cc(C2(C)OCCO2)ccc1C(=O)Nc1ccccc1C(=O)Nc1ccc(Cl)cn1>>COCOc1cc(C(C)=O)ccc1C(=O)Nc1ccccc1C(=O)Nc1ccc(Cl)cn1,,C1CCOC1,,Cl,,test
US20030036542A1,CC(C)c1cccc(C(C)C)c1N.COc1cc2c(cc1OC)-c1cc(Cl)nc(=O)n1CC2>>COc1cc2c(cc1OC)-c1cc(=Nc3c(C(C)C)cccc3C(C)C)[nH]c(=O)n1CC2,,CC(C)O,,,,test
US20140057914A1,CN1CCNCC1.Cn1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nc1Cc1ccnc(Cl)c1>>CN1CCN(c2cc(Cc3nc(-c4nc(-c5ccc(OC(F)(F)F)cc5)no4)cn3C)ccn2)CC1,,CCN(C(C)C)C(C)C,,,,test
US20150166513A1,CC(C)NC(=O)Cn1cc(Nc2nccc(O)n2)cn1.O=P(Cl)(Cl)Cl>>CC(C)NC(=O)Cn1cc(Nc2nccc(Cl)n2)cn1,,CC#N,,C1COCCO1,Cl,test
US20120009151A1,CCCc1nc(Cl)nc(Cl)n1.Nc1ccc(F)c(Cl)c1>>CCCc1nc(N)nc(Cl)n1,,C1CCOC1,O,CCN(CC)CC,,test
US20110152290A1,COC(=O)C1(NC(=O)c2ccc(OC)c(C=O)c2)Cc2ccccc2C1>>COC(=O)C1(NC(=O)c2ccc(OC)c(CO)c2)Cc2ccccc2C1,,C1CCOC1,,CO,[BH4-].[Na+],test
US20090186900A1,CCc1cc(-c2ccc3c(c2)CC(CC(=O)O)C3=O)ccc1OC.NCc1ccccn1>>CCc1cc(-c2ccc3c(c2)CC(CC(=O)NCc2ccccn2)C3=O)ccc1OC,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US04426321,C=CC(C)=CCCl.CC(=O)C(C)(C)C>>C=CC(C)=CCCC(=O)C(C)(C)C,,Cc1ccccc1,,[K+].[OH-],,test
US20030087932A1,COc1c(O[Si](C(C)C)(C(C)C)C(C)C)cccc1C(=O)C1CCN(C(=O)Cc2ccc(F)cc2)CC1>>COc1c(O[Si](C(C)C)(C(C)C)C(C)C)cccc1C(O)C1CCN(CCc2ccc(F)cc2)CC1,,Cc1ccccc1,,,,test
US20030018034A1,CC(=O)N1CCN(c2nc(N(C)C)cc(N(C)C)n2)CC1>>CN(C)c1cc(N(C)C)nc(N2CCNCC2)n1,,CCO,,O,[Na+].[OH-],test
US20050187272A1,CC(C)(C)c1cc(CBr)cc(C(C)(C)C)c1O.O=[N+]([O-])c1ccc(N2CCNCC2)cc1>>CC(C)(C)c1cc(CN2CCN(c3ccc([N+](=O)[O-])cc3)CC2)cc(C(C)(C)C)c1O,,CN(C)C=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20060116515A1,CN(CCO)Cc1ccc2c(c1)OCO2.O=S(Cl)Cl>>CN(CCCl)Cc1ccc2c(c1)OCO2.Cl,,ClCCl,,,,test
US20140350002A1,CN1c2nc(C3CC4CNCC4C3)ccc2N(CC2CC2(F)F)S1(=O)=O.C[C@@H](O)C(=O)O>>C[C@@H](O)C(=O)N1CC2CC(c3ccc4c(n3)N(C)S(=O)(=O)N4CC3CC3(F)F)CC2C1,,CC#N,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050096337A1,CCOC(=O)C(C)(C)Oc1ccc(O)cc1C.Cc1nc(-c2ccc(OC(F)(F)F)cc2)ccc1CCl>>CCOC(=O)C(C)(C)Oc1ccc(OCc2ccc(-c3ccc(OC(F)(F)F)cc3)nc2C)cc1C,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150080549A1,CC(=O)OC(C)=O.CC(C)(C)SSC[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)O>>CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CSSC(C)(C)C)C(=O)O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090227616A1,CC(C)(C)OC(=O)NCC1(CO)CC1.CCn1c(-c2nonc2N)nc2c(Cl)ncc(O)c21>>CCn1c(-c2nonc2N)nc2c(Cl)ncc(OCC3(CNC(=O)OC(C)(C)C)CC3)c21,,C1CCOC1,ClCCl,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090203737A1,CC(C)(C)OC(=O)N1CCC[C@H](c2noc(-c3cc(C#N)c[nH]3)n2)C1.Cl>>Cl.N#Cc1c[nH]c(-c2nc([C@H]3CCCNC3)no2)c1,,C1COCCO1,,,,test
US20100056377A1,Clc1ccc2nc(Cl)nc(-c3ccccc3)c2c1.NCc1ccco1>>Clc1ccc2nc(NCc3ccco3)nc(-c3ccccc3)c2c1,,O,,,,test
US05254558,CC(C)C(NC(=O)Cn1c(-c2ccccc2)ncc(N)c1=O)C(=O)C(F)(F)F.O=C=NS(=O)(=O)Cl>>CC(C)C(NC(=O)Cn1c(-c2ccccc2)ncc(NC(N)=O)c1=O)C(=O)C(F)(F)F,,C1CCOC1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US07893062B2,CN(C(=O)C(C)(C)c1cc(Cl)cc(Cl)c1)[C@@H]1CNC[C@H]1c1ccc(F)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CN(C(=O)C(C)(C)c1cc(Cl)cc(Cl)c1)C1CN(C(=O)Cl)CC1c1ccc(F)cc1,,ClCCl,,c1ccncc1,,test
US20150329506A1,Cc1nocc1[C@H](O)C[C@](C)(N)c1ccc(F)cc1F.O=C(N=C=S)c1ccccc1>>Cc1nocc1[C@H](O)C[C@](C)(NC(=S)NC(=O)c1ccccc1)c1ccc(F)cc1F,,ClCCl,,,,test
US20100190763A1,NC1CC1.O=C(O)c1ccc(N2CCN(Cc3cnc4c(c3)NC(=O)[C@@H]3CCCN43)CC2)cc1>>O=C(NC1CC1)c1ccc(N2CCN(Cc3cnc4c(c3)NC(=O)[C@@H]3CCCN43)CC2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110028469A1,COC(=O)c1sccc1N.Cc1ccc(S(=O)(=O)Cl)cc1F>>COC(=O)c1sccc1NS(=O)(=O)c1ccc(C)c(F)c1,,ClCCl,O,c1ccncc1,,test
US20120046267A1,C=O.CC1(C)OB(c2cnn(C3CCNCC3)c2)OC1(C)C>>CN1CCC(n2cc(B3OC(C)(C)C(C)(C)O3)cn2)CC1,,CO,,[BH4-].[Na+],,test
US20140187553A1,CC(C)(N=C=S)c1ccccc1.NN>>CC(C)(NC(=S)NN)c1ccccc1,,CCO,,,,test
US05703208,CC(C)(C)OC(=O)N[C@H]1CCCN(CC(=O)OCc2ccccc2)C1=O.Cl>>Cl.N[C@H]1CCCN(CC(=O)OCc2ccccc2)C1=O,,CCOC(C)=O,,,,test
US20070010670A1,CC(C)(C)[Si](C)(C)Cl.Nc1cc(S(=O)(=O)N2CCCC2)ccc1O>>CC(C)(C)[Si](C)(C)Oc1ccc(S(=O)(=O)N2CCCC2)cc1N,,CN(C)C=O,,O,c1c[nH]cn1,test
US20010007873A1,CC(C)(C)[Si](C)(C)Cl.COc1cc(OCc2ccccc2)c(O)cc1Br>>COc1cc(OCc2ccccc2)c(O[Si](C)(C)C(C)(C)C)cc1Br,,CN(C)C=O,,c1c[nH]cn1,,test
US07074800B1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCCCC1.Oc1cccc2[nH]ccc12>>COc1cc2c(Oc3cc4ccccc4[nH]3)ncnc2cc1OCCCN1CCCCC1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20020013496A1,COc1ccc(N)cc1OC.O=[N+]([O-])c1cc(S(=O)(=O)Cl)cc(F)c1OC(F)(F)F>>COc1ccc(NS(=O)(=O)c2cc(F)c(OC(F)(F)F)c([N+](=O)[O-])c2)cc1OC,,CO,,,,test
US05998433,CN(C)Cc1cc2c(o1)CN(C(=O)CCCCSc1ccccc1)CC2.Cl>>CN(C)Cc1cc2c(o1)CN(C(=O)CCCCSc1ccccc1)CC2.Cl,,CCOC(C)=O,CO,,,test
US20030036652A1,Nc1nc(Cl)ccc1[N+](=O)[O-]>>Nc1ccc(Cl)nc1N,[Zn],CC(=O)O,CO,,,test
US20140010783A1,CI.CS(=O)(=O)Nc1cccc(N=C=S)c1.N#CN>>CSCN(NC#N)c1cccc(NS(C)(=O)=O)c1,,CO,,C[O-].[Na+],,test
US20080171761A1,CCOC(=O)c1cc(OC(C)=O)c2ccn(C3CC3)c2c1>>CCOC(=O)c1cc(O)c2ccn(C3CC3)c2c1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20160237057A1,C1CCNCC1.C=O.O=Cc1ccc(O)cc1>>O=Cc1ccc(O)c(CN2CCCCC2)c1,,CCO,,,,test
US20060189628A1,CC(=O)N1CCC(=O)CC1.C[Si](C)(C)OC(C#N)c1ccc(Cl)cc1F>>CC(=O)N1CCC(O)(C(=O)c2ccc(Cl)cc2F)CC1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20090062251A1,CC1CCN(C(=O)c2ccc3[nH]c4c(c3c2)CC(C2CCCCC2)CC4)CC1.CCI>>CCn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CC(C1CCCCC1)CC2,,C1CCOC1,,[H-].[Na+],,test
US20130217666A1,BrBr.O=C1CCCOc2cc(F)c(Br)cc21>>O=C1c2cc(Br)c(F)cc2OCCC1Br,,ClCCl,,,,test
US20020103229A1,CN(C)c1ccc(-c2n[nH]c3ccc(C(N)=O)cc23)cc1.COC(OC)N(C)C.NN>>CN(C)c1ccc(-c2n[nH]c3ccc(-c4ncn[nH]4)cc23)cc1,,CC(=O)O,,,,test
US05869493,C(=NC1CCCCC1)=NC1CCCCC1.CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)OCC[C@@H](CO)Cn1cnc2c(=O)[nH]c(N)nc21.CCCC(=O)O>>CCCCOC(=O)N[C@H](C(=O)OCC[C@@H](COC(=O)CCC)Cn1cnc2c(=O)[nH]c(N)nc21)C(C)C,,ClCCl,,,,test
US06133253,Cc1ccc(S(=O)(=O)O)cc1.O=C(OCc1ccccc1)N1CC[C@H]1COc1ccc(F)nc1>>CN1CC[C@H]1COc1ccc(F)nc1.Cc1ccc(S(=O)(=O)O)cc1,,CO,,,,test
US05155117,BrCc1ccc(Br)nc1.CCCCc1n[nH]c(CCCC)n1>>CCCCc1nc(CCCC)n(Cc2ccc(Br)nc2)n1,,CN(C)C=O,CO,[H][H],[H-].[Na+],test
US20120220616A1,CCOC(=O)c1ncc(C)o1.O=C1CCC(=O)N1Br>>CCOC(=O)c1ncc(CBr)o1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20070299072A1,COc1ccc(CCN2C(=O)C3(CCN(C(=O)OC(C)(C)C)CC3)N(C)C2Cc2ccc(C(C)(C)C)cc2)cc1>>COc1ccc(CCN2C(=O)C3(CCNCC3)N(C)C2Cc2ccc(C(C)(C)C)cc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20140128390A1,CC1(C)CNCCN1.Clc1ncnc2cc(Br)sc12>>CC1(C)CN(c2ncnc3cc(Br)sc23)CCN1,,CC#N,CCN(CC)CC,,,test
US20040063643A1,C=C(C)c1cccc(C(C)C)c1NC(=O)N(Cc1ccccc1)CC1(c2ccccn2)CCCCC1.O=O>>CC(=O)c1cccc(C(C)C)c1NC(=O)N(Cc1ccccc1)CC1(c2ccccn2)CCCCC1,,ClCCl,,,,test
US20110077410A1,COC(=O)C(F)F.Cc1ccc(NN)c(C)c1>>Cc1ccc(NNC(=O)C(F)F)c(C)c1,,CCO,,,,test
US20110076291A1,CC(C)(C)OC(=O)N1CCC=C(OS(=O)(=O)C(F)(F)F)C1.Cc1nc(-c2nc3c(s2)CCOc2cc(B4OC(C)(C)C(C)(C)O4)ccc2-3)n(C(C)C)n1>>Cc1nc(-c2nc3c(s2)CCOc2cc(C4=CCCN(C(=O)OC(C)(C)C)C4)ccc2-3)n(C(C)C)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,ClCCl,O=C([O-])[O-].[Na+].[Na+],test
US20010039344A1,COC(=O)C(CC1CCCC1)c1ccc(S(=O)(=O)C(F)(F)F)cc1>>O=C(O)C(CC1CCCC1)c1ccc(S(=O)(=O)C(F)(F)F)cc1,,C1CCOC1,,[Li+].[OH-],,test
US20100317673A1,CCOC(=O)c1cn2cc(Cl)ccc2n1.Nc1cnccn1>>O=C(Nc1cnccn1)c1cn2cc(Cl)ccc2n1,,Cc1ccccc1,,C[Al](C)C,,test
US20010027196A1,NCc1ccccc1.Nc1nc(OS(=O)(=O)C(F)(F)F)c([N+](=O)[O-])c(-c2ccco2)n1>>Nc1nc(NCc2ccccc2)c([N+](=O)[O-])c(-c2ccco2)n1,,C1COCCO1,,,,test
US20050282808A1,CN[C@@H]1CC[C@@H](C(=O)Nc2c(C(=O)Nc3ccc(Cl)cn3)oc3ccccc23)CC1.OCCI>>CN(CCO)[C@@H]1CC[C@@H](C(=O)Nc2c(C(=O)Nc3ccc(Cl)cn3)oc3ccccc23)CC1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US04798619,CC(C)C(C)(NC(=O)c1ccc2ccccc2n1)C(N)=O>>CC(C)C1(C)N=C(c2ccc3ccccc3n2)NC1=O,,Cc1ccccc1C,,O,[H-].[Na+],test
US05741926,Nc1ccccc1F.O=C(CBr)Nc1ccc([N+](=O)[O-])cc1>>O=C(CNc1ccccc1F)Nc1ccc([N+](=O)[O-])cc1,,CN(C)C=O,,,,test
US20110301143A1,CC(C)(C)OC(=O)N1CCC(C(=O)c2cc(OC(F)(F)F)ccc2C2CC2)CC1.Cl>>Cl.O=C(c1cc(OC(F)(F)F)ccc1C1CC1)C1CCNCC1,,C1COCCO1,,,,test
US20100311732A1,COC(=O)CN(Cc1ccc(F)cc1[N+](=O)[O-])C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N(CC(=O)O)Cc1ccc(F)cc1[N+](=O)[O-],,C1CCOC1,O,Cl,[Li+].[OH-],test
US20060229335A1,COc1ccc([N+](=O)[O-])cc1-c1ccnn1C.O=C1CCC(=O)N1Br>>COc1ccc([N+](=O)[O-])cc1-c1c(Br)cnn1C,,CCOC(C)=O,CN(C)C=O,CCCCCC,,test
US04540692,COC(=O)C1=C(O)c2ccccc2S(=O)(=O)N1C.COc1ccc(N)c(=O)cc1>>COc1ccc(NC(=O)C2=C(O)c3ccccc3S(=O)(=O)N2C)c(=O)cc1,,Cc1ccccc1C,,,,test
US20070093481A1,CC(=O)OC(C)=O.COC(OC)[C@]1(C)Oc2ccc(N)cc2[C@H](n2c(=S)oc3ccccc32)[C@H]1O>>COC(OC)[C@]1(C)Oc2ccc(NC(C)=O)cc2[C@H](n2c(=S)oc3ccccc32)[C@H]1O,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20080275037A1,Cc1nc(C(F)(F)F)ccc1CO.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>Cc1nc(C(F)(F)F)ccc1CN=[N+]=[N-],,C1CCOC1,C1CCOC1,C1CCC2=NCCCN2CC1,,test
US20130172302A1,O=C(CCl)c1ccccc1.O=C(O[C@H]1CN2CCC1CC2)C(c1ccc(F)cc1F)N1CCCCC1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C(c1ccc(F)cc1F)N1CCCCC1)C2)c1ccccc1.[Cl-],,CC#N,,,,test
US20110053950A1,Cc1onc(N)c1C.O=C(Cl)Oc1ccccc1>>Cc1onc(NC(=O)Oc2ccccc2)c1C,,C1CCOC1,CC#N,CCN(CC)CC,,test
US20090264428A1,COC(=O)c1ccc(CN(C(=O)OC(C)(C)C)C(C)C)cc1>>CC(C)N(Cc1ccc(C(=O)O)cc1)C(=O)OC(C)(C)C,,CCO,,[Na+].[OH-],,test
US04153794,Nc1ccccc1CN1CCN(CC(=O)N2CCOCC2)CC1.O=C(Cl)c1ccccc1>>O=C(Nc1ccccc1CN1CCN(CC(=O)N2CCOCC2)CC1)c1ccccc1,,c1ccncc1,,,,test
US20080312226A1,Cc1noc(NC(=O)OCC(Cl)(Cl)Cl)c1C.FC(F)(F)c1cccc(-c2csc(N3CCNCC3)n2)c1>>Cc1noc(NC(=O)N2CCN(c3nc(-c4cccc(C(F)(F)F)c4)cs3)CC2)c1C,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20100035906A1,Cc1ccnc(F)c1.NN>>Cc1ccnc(NN)c1,,CCOCCO,,O,,test
US04910019,CC(C#N)c1ccc2ccccc2c1.CI>>CC(C)(C#N)c1ccc2ccccc2c1,,C1CCOC1,,[Li]CCCC,,test
US20060030613A1,CC(C)(C)c1ccc(C=O)cc1.CCOc1cccc(CCN)c1>>CCOc1cccc(CCNCc2ccc(C(C)(C)C)cc2)c1,,CO,,Cl,[BH4-].[Na+],test
US05547960,C=CCC1CC2(Cc3ccc(OC)nc31)OCCO2>>CCCC1CC2(Cc3ccc(OC)nc31)OCCO2,[Pd],CCO,,[H][H],,test
US20100137282A1,CN(C)C=O.Fc1c(Br)ccc2c1OCCO2>>O=Cc1ccc2c(c1F)OCCO2,,C1CCOC1,,[Li]CCCC,,test
US20070099944A1,NN.O=C(Nc1cccc(F)c1)c1cc([N+](=O)[O-])ccc1F>>O=[N+]([O-])c1ccc2[nH]nc(Nc3cccc(F)c3)c2c1,,CCO,,O,,test
US20160016937A1,CC(=O)Cl.CN(C)c1ccncc1.ClCCl.c1ccc2c(c1)CNN2>>CC(=O)N1CC2(CC2)c2cnc(Cl)cc21,CN(C)c1ccncc1,,,CCN(CC)CC,,test
US20130102776A1,COc1ccc2c(c1C#CC1CCN(C(=O)OC(C)(C)C)CC1)OCC2=O.O=Cc1n[nH]c2ccccc12>>COc1ccc2c(c1C#CC1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccccc13)C2=O,C1CCNCC1,CO,,,,test
US20150045377A1,FC(F)(F)CI.O=c1[nH]cnc2occ(-c3ccccc3)c12>>O=c1c2c(-c3ccccc3)coc2ncn1CC(F)(F)F,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US09266853B2,CC#CCOc1ccc(C[C@H](NC(=O)[C@@H](/C=C/CCCCCCC(=O)CCCCCCC)[C@@](O)(CCO)C(=O)OC(C)(C)C)C(=O)OC)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC#CCOc1ccc(C[C@H](NC(=O)[C@@H](/C=C/CCCCCCC(=O)CCCCCCC)[C@@](O)(CCOC(C)=O)C(=O)O)C(=O)OC)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US04642313,CC(C)O.O=C(O)Cc1nc(-c2ccc(Cl)cc2)oc1-c1ccco1>>CC(C)OC(=O)Cc1nc(-c2ccc(Cl)cc2)oc1-c1ccco1,,C1CCOC1,O,CCN(CC)CC,C[n+]1ccccc1Cl.[I-],test
US20160068496A1,C1COCCN1.COc1cc(Br)cc2c(Cl)nc(Cl)nc12>>COc1cc(Br)cc2c(N3CCOCC3)nc(Cl)nc12,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04022901,Nc1ccc(-c2nc(-c3cccnc3)no2)cc1.S=C(Cl)Cl>>S=C=Nc1ccc(-c2nc(-c3cccnc3)no2)cc1,,C1CCOC1,,,,test
US05876945,CC(C)C[C@H](NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)O.C[C@H](N)C(=O)CCl>>CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)CCl,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US06265411B1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCOCC1.O=C1Cc2ccc(F)cc2N1>>COc1cc2c(C3C(=O)Nc4cc(F)ccc43)ncnc2cc1OCCCN1CCOCC1.Cl,,C1CCOC1,,CN(C)C=O,[H-].[Na+],test
US20070197628A1,Fc1ccc(CNCC=Cc2ccc(Cl)cc2)cc1F.O=C(Cl)C=CC=Cc1ccc(Cl)cc1Cl>>O=C(C=CC=Cc1ccc(Cl)cc1Cl)N(CC=Cc1ccc(Cl)cc1)Cc1ccc(F)c(F)c1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20130196998A1,CCCCCCBr.Oc1ccc2c(c1)C1(CCN(Cc3ccccc3)CC1)CO2>>CCCCCCOc1ccc2c(c1)C1(CCN(Cc3ccccc3)CC1)CO2,,CO,,Br,[Na+].[OH-],test
US20110015202A1,COc1cnn(C)c(=O)c1Cl>>COc1cnn(C)c(=O)c1,[Pd],CCO,,CCN(CC)CC,,test
US20140194290A1,CCSc1cccnc1-c1nc2cc(C(F)(F)F)cnc2n1C.O=C(OO)c1cccc(Cl)c1>>CCS(=O)c1cccnc1-c1nc2cc(C(F)(F)F)cnc2n1C,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20020082420A1,CC(C)(C)OC(=O)NCCCBr.CCOC(=O)CNC>>CCOC(=O)CN(C)CCCNC(=O)OC(C)(C)C,,CC#N,,Cl,,test
US20040067901A1,CC(=O)OC(C)(C)C(=O)Br.Nc1nc(Cl)c2ccn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1>>COc1nc(N)nc2c1ccn2[C@@H]1O[C@H](CO)[C@H]2O[C@H]21,,CC#N,,O,O=C([O-])O.[Na+],test
US20160068531A1,Cc1ccc(S(=O)(=O)OCCCS(C)(=O)=O)cc1.Nc1ccc(Cl)cc1[N+](=O)[O-]>>CC(CNc1ccc(Cl)cc1[N+](=O)[O-])S(C)(=O)=O,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090131458A1,CCCCCNc1nc(N)c2nc(OC)n(C3CCCCO3)c2n1.O=C(O)C(F)(F)F>>CCCCCNc1nc(N)c2nc(OC)[nH]c2n1.O=C(O)C(F)(F)F,,CO,,,,test
US20110251418A1,Nc1cccc(Cl)c1.O=S(=O)(O)O>>Nc1ccc(S(=O)(=O)O)c(Cl)c1,,O,,,,test
US20070197617A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(C(=O)O)C(C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)C(N)(C(=O)O)C(C(F)(F)F)C(F)(F)F,,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US03948854,CCCCCCCCCCCCCCCCCCOC(=O)Cl.NNC(=O)c1cc(O)ccc1O>>CCCCCCCCCCCCCCCCCCOC(=O)N(N)C(=O)c1cc(O)ccc1O,,CC(=O)N(C)C,,CCN(CC)CC,O,test
US06319902B1,Cc1oc(=O)oc1COC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C>>Cc1oc(=O)oc1COC(=O)[C@@H]1CCCN1,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US20040132727A1,COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.c1ccc(N2CCNCC2)cc1>>COc1cc2ncnc(Oc3ccc(NC(=O)N4CCN(c5ccccc5)CC4)cc3)c2cc1OC,,ClC(Cl)Cl,O,CCN(CC)CC,,test
US20100009943A1,CCCCCC(C)=O.COC(C)=O>>CCCCCC(=O)CC(C)=O,,CCOCC,,Cl,,test
US20040053890A1,CCCCCBr.O=C(c1cccc2ccccc12)c1ccc(O)c2ccccc12>>CCCCCOc1ccc(C(=O)c2cccc3ccccc23)c2ccccc12,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080171772A1,CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(C(=O)O)cc2n1Cc1ccccc1.NCCO>>CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(C(=O)NCCO)cc2n1Cc1ccccc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20100280019A1,Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)nn1.NN1CCOCC1>>Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NN2CCOCC2)nn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20090168066A1,C=C(N)C(=O)O.N[C@@H](CO)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O.O>>NC(=O)CC[C@H](N)C(=O)O.O=C1CC[C@@H](C(=O)O)N1,,O,,,,test
US20090247507A1,Nc1ncc(Br)c(N2CCN(CC(=O)Nc3nccs3)CC2)c1[N+](=O)[O-]>>Nc1ncc(Br)c(N2CCN(CC(=O)Nc3nccs3)CC2)c1N,,CCO,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US04234587,CSCc1nc(C)c(C(C)C)c(OC(=O)N(C)C)n1.OO>>Cc1nc(CS(C)=O)nc(OC(=O)N(C)C)c1C(C)C,,CC(=O)O,,,,test
US20120108567A1,CC(C)(C)OC(=O)NN.N#CC(O)C1CC1>>CC(C)(C)OC(=O)NN=CC1CC1,,CO,,,,test
US20140275234A1,C=CCNCC=C.COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O.COc1ccccc1>>C=CCN(/C=C1/C(=O)O[C@H](COC)[C@@]2(C)C1=C(O)C(=O)C1=C2[C@H](OC(C)=O)C[C@]2(C)C(=O)CC[C@@H]12)CC=C.COc1ccccc1,,C1CCOC1,,,,test
US20150148358A1,Cc1nc(CN)cc(Oc2ccc(CS(=O)(=O)N(C)C(=O)OC(C)(C)C)cc2)n1.Clc1cnc(Cl)nc1>>CNS(=O)(=O)Cc1ccc(Oc2cc(CNc3ncc(Cl)cn3)nc(C)n2)cc1,,CS(C)=O,,[F-].[K+],,test
US06884868B1,BrCCCCCCCBr.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OCCCCCCCBr)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040152646A1,COc1ccc(Cl)cc1[C@]1(F)C(=O)N([C@@H]2O[C@H](COCc3ccccc3)[C@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OP(=O)(OCc2ccccc2)OCc2ccccc2)c2cc(C(F)(F)F)ccc21>>COc1ccc(Cl)cc1[C@]1(F)C(=O)N([C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OP(=O)(O)O)c2cc(C(F)(F)F)ccc21,O=[Pt],CCOC(C)=O,,,,test
US20070185144A1,CC(C)(C)OC(=O)N1[C@@H](Cc2cscn2)[C@@H](CO[Si](C)(C)C(C)(C)C)OC1(C)C.CI>>Cc1nc(C[C@H]2[C@@H](CO[Si](C)(C)C(C)(C)C)OC(C)(C)N2C(=O)OC(C)(C)C)cs1,,C1CCOC1,,[Li]CCCC,,test
US20150291563A1,CS(=O)(=O)Cl.OC(C1=NN(c2ccc(F)cc2F)C(c2ccc(N3CCCNCC3)cc2)C1)(C(F)(F)F)C(F)(F)F>>CS(=O)(=O)N1CCCN(c2ccc(C3CC(C(O)(C(F)(F)F)C(F)(F)F)=NN3c3ccc(F)cc3F)cc2)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20150255720A1,BrBr.CC1(C)c2ccccc2-c2cc3c(cc21)-c1c(cc(-c2ccccc2)c2ccccc12)C3(C)C>>CC1(C)c2cc(Br)ccc2-c2cc3c(cc21)-c1c(cc(-c2ccccc2)c2ccccc12)C3(C)C,,ClC(Cl)Cl,,O,,test
US20070299068A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=S1(=O)CCC(O)CC1>>Cc1ccc(S(=O)(=O)OC2CCS(=O)(=O)CC2)cc1,,c1ccncc1,,,,test
US20080221190A1,CCC(O)CC1(Cl)C=CC(Cl)=CC1.Cc1ccccc1.c1c[nH]cn1>>OC(CCc1ccc(Cl)cc1)Cn1ccnc1,,Cc1ccccc1,,[Na+].[OH-],,test
US20120208819A1,NCc1ccc(F)c(F)c1.Nc1ncc(Br)nc1C(=O)O>>Nc1ncc(Br)nc1C(=O)NCc1ccc(F)c(F)c1,,CCOC(C)=O,O,CCN(C(C)C)C(C)C,CN(C)C=O,test
US20130035358A1,COC(=O)c1cc(C(=O)c2ccc(N(C)c3ccc(Cl)cc3)cn2)ccc1C(=O)c1ccccc1>>CN(c1ccc(Cl)cc1)c1ccc(C(=O)c2ccc(C(=O)c3ccccc3)c(C(=O)O)c2)nc1,,CCO,O,[Na+].[OH-],,test
US04514573,NCc1cccc2ccccc12.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NCc1cccc2ccccc12)C(F)(F)F,,O,,c1ccncc1,,test
US20110172233A1,C=CCCC(=O)N[C@@H](COC(=O)[C@@H](CC=C)CC(=O)OC(C)(C)C)c1ccccc1>>CC(C)(C)OC(=O)C[C@@H]1CC=CCCC(=O)N[C@H](c2ccccc2)COC1=O,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,Cc1ccccc1,ClCCl,,,test
US20080023046A1,Nc1nc(F)nc2nc[nH]c12.O=c1cc[nH]c(=O)n1C1OC[C@@H](O)[C@@H](O)[C@@H]1O>>Nc1nc(F)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O,,O=P([O-])([O-])[O-],,CN(C)C=O,,test
US04666962,COC(=O)CCON(Cc1ccccc1)Cc1ccccc1>>O=C(O)CCON(Cc1ccccc1)Cc1ccccc1,,C1CCOC1,O,[K+].[OH-],,test
US20070185155A1,BrCCOCc1ccccc1.COc1cccc(C(O)(c2cccc(OC)c2)C23CCN(CC2)CC3)c1>>COc1cccc(C(O)(c2cccc(OC)c2)C23CC[N+](CCOCc4ccccc4)(CC2)CC3)c1.[Br-],,CC#N,,,,test
US20080287547A1,NCC1(C(N)c2ccccc2)CCCC1.O=C(O)c1cccc(C(F)(F)F)c1Cl>>CNC1(C(NC(=O)c2cccc(C(F)(F)F)c2Cl)c2ccccc2)CCCC1,,CCN(C(C)C)C(C)C,CN(C)C=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20050049243A1,CONc1cc(C2CC2)c(C(F)(F)F)cc1[N+](=O)[O-].CS(C)=O.Nc1cc(Cl)c(C(F)(F)F)cc1[N+](=O)[O-].O=C(O)C(F)(F)F.OCC1CC1>>CC(C)(C)OC(=O)Nc1cc(OCC2CC2)c(C(F)(F)F)cc1[N+](=O)[O-],,CS(C)=O,ClCCl,[K+].[OH-],,test
US09233968B1,CC(=O)OC(C)=O.Nc1cn2nc(I)ccc2n1>>CC(=O)Nc1cn2nc(I)ccc2n1,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US04281008,CCCc1c(OCc2ccccc2)ccc2c(=O)cc(CCC(=O)OCC)oc12>>CCCc1c(O)ccc2c(=O)cc(CCC(=O)OCC)oc12,,ClCCl,,ClB(Cl)Cl,,test
US20140288045A1,COc1cc(Cl)c(C2(C)CC2)cc1NC(C)=O>>COc1cc(Cl)c(C2(C)CC2)cc1N,,O,,CCO,[K+].[OH-],test
US20070244095A1,Cc1cc2c(cc1C(F)(F)F)N(C(=O)OC(C)(C)C)CCC[C@@H]2N.O=Cc1cc(F)cc(C(F)(F)F)c1>>Cc1cc2c(cc1C(F)(F)F)N(C(=O)OC(C)(C)C)CCC[C@@H]2NCc1cc(F)cc(C(F)(F)F)c1,,CC(Cl)Cl,,CC(=O)O,O=C([O-])O.[Na+],test
US20160120850A1,C[Si](C)(C)C(F)(F)F.O=C(c1ccc(Br)c(Cl)c1Cl)C(F)(F)F>>OC(c1ccc(Br)c(Cl)c1Cl)(C(F)(F)F)C(F)(F)F,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20160272628A1,CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)c2ccc(F)cc21.CC1c2cc(Br)ccc2S(=O)(=O)N1CCN1CCOC1=O>>CC1c2cc(-c3cn(C(=O)OC(C)(C)C)c4cc(F)ccc34)ccc2S(=O)(=O)N1CCN1CCOC1=O,,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20060235225A1,C1CCC2=NCCCN2CC1.CN(C)C=O.COC(OC)N(C)C.Cn1cc(CC(=O)c2ccco2)ccc1=O>>Cn1cc(-c2cnc(N)nc2-c2ccco2)ccc1=O,,CC(C)O,,,,test
US20080318943A1,CCCC[Sn](Cl)(CCCC)CCCC.COc1ccncn1>>CCCC[Sn](CCCC)(CCCC)c1cncnc1OC,,CCOCC,,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US20140228377A1,C[C@@H]1CC[C@@H](c2nc3cc(Cl)ccc3o2)CN1.O=C(O)c1cc(Cl)ccc1-c1ncccn1>>C[C@@H]1CC[C@@H](c2nc3cc(Cl)ccc3o2)CN1C(=O)c1cc(Cl)ccc1-c1ncccn1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20130172292A1,CCn1nc(-c2ccc(OC)nc2)c2ncccc21>>CCn1nc(-c2ccc(O)nc2)c2ncccc21,,CO,,Cl,,test
US20140315965A1,CCOC(=O)COc1ccc(C(CC)(CC)c2ccc(OCC(=O)O)c(C)c2)cc1C>>CCOC(=O)COc1ccc(C(CC)(CC)c2ccc(OCCO)c(C)c2)cc1C,,C1CCOC1,,B,,test
US20160039838A1,COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1[N+](=O)[O-]>>COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1N,[Ni],CO,,,,test
US20050261276A1,CC(CC=O)C(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1.CN>>CNCCC(C)C(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130085141A1,O=S(=O)(Cl)c1cccc(C(F)(F)F)c1.O[C@H]1C[C@@H]2CNCCN2C1>>O=S(=O)(c1cccc(C(F)(F)F)c1)N1CCN2C[C@@H](O)C[C@@H]2C1,,ClCCl,,CCN(CC)CC,,test
US20060111347A1,COC(=O)/C=C/C1(S(=O)(=O)c2ccc3ccccc3c2)CC1>>O=C(O)/C=C/C1(S(=O)(=O)c2ccc3ccccc3c2)CC1,,C1COCCO1,,Cl,,test
US20020049197A1,Fc1ccc(Nc2ncnc3cc(OCCN4CCNCC4)c(OCC4CCCC4)cc23)cc1Cl.O=C1CC[C@@H](C(=O)O)O1>>O=C1CC[C@@H](C(=O)N2CCN(CCOc3cc4ncnc(Nc5ccc(F)c(Cl)c5)c4cc3OCC3CCCC3)CC2)O1,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US05858995,CCOC(=O)C=Cc1c(C)oc2c([N+](=O)[O-])cccc12>>CCOC(=O)CCc1c(C)oc2c(N)cccc12,[Pd],C1COCCO1,CCO,,,test
US20120035196A1,COCOc1cc(C)c(-c2cccc(COc3ccc4c(c3)CC3(CC3)C4CC#N)c2C)c(C)c1>>Cc1cc(O)cc(C)c1-c1cccc(COc2ccc3c(c2)CC2(CC2)C3CC#N)c1C,,C1CCOC1,CO,Cl,,test
US05284863,O=S(=O)(c1cc[nH]c1-c1ccc(Cl)cc1)C(F)(F)F.O=[N+]([O-])O>>O=[N+]([O-])c1cc(S(=O)(=O)C(F)(F)F)c(-c2ccc(Cl)cc2)[nH]1,,CC(=O)OC(C)=O,,O,,test
US20100010035A1,CCCc1ccc(S(=O)(=O)Cl)s1.Cc1onc(N)c1C>>CCCc1ccc(S(=O)(=O)Nc2noc(C)c2C)s1,,ClCCl,c1ccncc1,CN(C)c1ccccn1,,test
US20110182850A1,CC(C)(C)OC(=O)N[C@H](C(=O)O)C1CCCCC1.CCCC1(S(=O)(=O)NC(=O)[C@@]2(NC(=O)[C@@H]3C[C@@]4(CN3C(=O)[C@@H](N)C(C)(C)C)C(C)(C)C43CCC3)C[C@@H]2CC)CC1>>CCCC1(S(=O)(=O)NC(=O)[C@@]2(NC(=O)[C@@H]3C[C@@]4(CN3C(=O)[C@@H](NC(=O)[C@@H](NC(=O)OC(C)(C)C)C3CCCCC3)C(C)(C)C)C(C)(C)C43CCC3)C[C@@H]2CC)CC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05252732,Brc1ccc2[nH]ccc2c1.C=CCI>>C=CCn1ccc2cc(Br)ccc21,,CS(C)=O,O,[Na+].[OH-],,test
US20060223801A1,CC(=O)OC(C)=O.CSc1nc(N)cc(Cl)n1>>CSc1nc(Cl)cc(NC(C)=O)n1,,O=C([O-])O,[Na+],,,test
US20060252715A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCC(=O)O[C@@H]1[C@@H](COC(C)=O)O[C@@H](n2cc([N+](=O)[O-])c3c(N)ncnc32)[C@@H]1OC(C)=O>>CCC(=O)O[C@@H]1[C@@H](COC(C)=O)O[C@@H](n2cc(NC(=O)OC(C)(C)C)c3c(N)ncnc32)[C@@H]1OC(C)=O,[Pd],CN(C)C=O,,,,test
US20090169567A1,BrCCCCCBr.CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N)CC1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](N2CCCCC2)CC1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US06433112B1,CC(C)P(Cl)C(C)C.[Li]C1C=CC=C1>>[Li]C1(P(C(C)C)C(C)C)C=CC=C1,,CCOCC,,CCCCCC,[Li]CCCC,test
US20070088185A1,Brc1ccc(I)cc1.OB(O)c1ccc2cc(-c3cccc4ccccc34)ccc2c1>>Brc1ccc(-c2ccc3cc(-c4cccc5ccccc45)ccc3c2)cc1,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20090036492A1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.O=Cc1ccc(OCc2ccccc2Cl)c2ccccc12>>COc1cc(O)c2c(c1C(=O)NCc1ccc(OCc3ccccc3Cl)c3ccccc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US06022906,CC(C)(C(=O)c1ccc(OCCCO)cc1)N1CCOCC1.II>>CC(C)(C(=O)c1ccc(OCCCI)cc1)N1CCOCC1,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110269758A1,Nc1ccc(NC(=O)c2ccccc2)cc1.Nc1ncnc(Cl)c1C=O>>Nc1ncnc(Nc2ccc(NC(=O)c3ccccc3)cc2)c1C=O,,CO,O,O=C([O-])O.[Na+],,test
US04931443,Cc1cccc(N2CCN(CCCCc3ccc(C(CCC(=O)O)=NO)cc3)CC2)c1>>Cc1cccc(N2CCN(CCCCc3ccc(C4CCC(=O)N4)cc3)CC2)c1,[Ni],CO,,[H][H],,test
US20030125565A1,C[C@]1(c2ccc(C=O)cc2)C(=O)N(CC(=O)OCc2ccccc2)C(=O)N1Cc1ccccc1>>C[C@]1(c2ccc(CO)cc2)C(=O)N(CC(=O)O)C(=O)N1Cc1ccccc1,,CCO,,O,[BH4-].[Na+],test
US20070010520A1,CC(C)(C)OC(=O)N1CC=C(c2cn3nc(-c4ccco4)nc3c(N)n2)CC1>>CC(C)(C)OC(=O)N1CCC(c2cn3nc(-c4ccco4)nc3c(N)n2)CC1,[Pd],CO,,,,test
US05719141,NCc1ccccc1N.O=COc1ccc([N+](=O)[O-])cc1>>Nc1ccccc1CNC=O,,ClCCl,,,,test
US20050014812A1,CCOC(=O)CCCOc1cc(C)c2nc(C)[nH]c2c1.FC(F)(F)c1cnc(CCl)c(Cl)c1>>CCOC(=O)CCCOc1cc(C)c2nc(C)n(Cc3ncc(C(F)(F)F)cc3Cl)c2c1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20120088809A1,COc1c(F)ccc(NC(=O)C(C)(C)C)c1CC(C)O>>CC1Cc2c(N)ccc(F)c2O1,,Br,,,,test
US20110028520A1,CC(C)(NC1=C[C@H](c2cccc(OC(F)(F)F)c2)N(c2ccc(C#N)cc2)C1=O)c1cccc(C(F)(F)F)n1>>CC(C)(N[C@@H]1C[C@H](c2cccc(OC(F)(F)F)c2)N(c2ccc(C#N)cc2)C1=O)c1cccc(C(F)(F)F)n1,,CC(=O)O,,[BH3-]C#N.[Na+],,test
US20050065032A1,CCC(Oc1cncc(Cl)c1)C(=O)OC>>CCC(Oc1cncc(Cl)c1)C(=O)O,,O,,[Na+].[OH-],,test
US20160157485A1,O=Cc1ccc(Cl)cc1Cl.[C-]#[N+]C1CC1>>Clc1ccc(C2OC=NC23CC3)c(Cl)c1,,C1CCOC1,C1CCOC1,[Li]CCCC,,test
US20160016908A1,CC(=O)N1c2ccc(C(=O)O)cc2[C@H](Nc2ccc(F)cn2)[C@@H](C)[C@@H]1C.[NH4+]>>CC(=O)N1c2ccc(C(N)=O)cc2[C@H](Nc2ccc(F)cn2)[C@@H](C)[C@@H]1C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160251340A1,CC1(C)Cc2c(Oc3ccc([N+](=O)[O-])cn3)cccc2O1>>CC1(C)Cc2c(Oc3ccc(N)cn3)cccc2O1,[Fe],C1CCOC1,O,[Cl-].[NH4+],,test
US20150252059A1,C=CCC1(CF)C(N)=N[C@](C)(c2cc([N+](=O)[O-])ccc2F)CS1(=O)=O.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=CCC1(CF)C(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)=N[C@](C)(c2cc([N+](=O)[O-])ccc2F)CS1(=O)=O,CN(C)c1ccncc1,ClCCl,,,,test
US20070208059A1,Cc1c(C(=O)Nc2ccc(C(F)(F)F)cn2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(O)cc1.O=S(=O)(Cl)CCC(F)(F)F>>Cc1c(C(=O)Nc2ccc(C(F)(F)F)cn2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1,,ClCCl,,CCN(CC)CC,O,test
US20030055047A1,O=S(Cl)Cl.[O-][n+]1cccc(CO)c1>>[O-][n+]1cccc(CCl)c1,,ClCCl,,,,test
US20070191372A1,CN(CCCN)CCCNC(=O)OC(C)(C)C.Cc1ccc2c(c1)nc(Cl)n[n+]2[O-]>>Cc1ccc2c(c1)nc(NCCCN(C)CCCNC(=O)OC(C)(C)C)n[n+]2[O-],,COCCOC,,CCN(CC)CC,,test
US20070203210A1,CCN.CCOC(=O)c1sc(-n2cnc3cc(OC)c(OC)cc32)nc1-c1ccccc1>>CCNC(=O)c1sc(-n2cnc3cc(OC)c(OC)cc32)nc1-c1ccccc1,,CO,,,,test
US20140080803A1,OCC1(c2cccc(OC(F)(F)F)c2)CC(F)(F)C1>>O=CC1(c2cccc(OC(F)(F)F)c2)CC(F)(F)C1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US20040121994A1,O=C(C[N+](=O)[O-])c1ccccc1.Sc1ccc(Cl)cc1>>CC(=O)c1ccccc1Sc1ccc(Cl)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040147608A1,COC(=O)C1(CNC(=O)OC(C)(C)C)CC1C(C)C>>CC(C)C1CC1(CNC(=O)OC(C)(C)C)C(=O)O,,CO,O,[Li+].[OH-],,test
US20030092046A1,NCCN.Nc1nc2c(ncn2[C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1>>Nc1nc(N)c2[nH]cnc2n1,,c1ccncc1,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US20110207715A1,Cc1cc(OCC2CCCCNC2)ccc1F.Cc1ccc(-n2nccn2)c(C(=O)O)c1>>Cc1ccc(-n2nccn2)c(C(=O)N2CCCCC(COc3ccc(F)c(C)c3)C2)c1,,CCOC(C)=O,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
US20150152112A1,C=CCBr.CC(=O)c1ccccc1C(=O)O>>C=CCOC(=O)c1ccccc1C(C)=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040133008A1,CC(C)(C)OC(=O)N(CCn1cccn1)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N(CCn1cccn1)c1ccc(N)cc1,[Pd],CO,,[H][H],,test
US20130210796A1,FC(F)(F)c1cccc(-n2nnnc2CCl)c1.N#CC1CCNC1>>Cl.N#CC1CCN(Cc2nnnn2-c2cccc(C(F)(F)F)c2)C1,,CC#N,,CCN(CC)CC,,test
US05344845,C1CCNCC1.COc1cc(C=CC(=O)Cl)ccc1OC(C)=O>>COc1cc(C=CC(=O)N2CCCCC2)ccc1OC(C)=O,,c1ccncc1,,Cl,,test
US20090286807A1,CS(=O)(=O)Cl.C[C@@H]1C[C@@H]([C@H](O)COCc2ccccc2)OC1=O>>C[C@@H]1C[C@@H]([C@@H](COCc2ccccc2)OS(C)(=O)=O)OC1=O,,ClCCl,,CCN(CC)CC,O,test
US20100022538A1,CN(C)/C=N/c1nc(OCOC(=O)C2CCCC2)ncc1F.O=C([O-])O>>O=CNc1nc(OCOC(=O)C2CCCC2)ncc1F,,C1COCCO1,,Cl,,test
US20100152165A1,CCOC(=O)CCc1ccc(NCc2cccc3c2CCCN3C=C(OC)c2ccccc2)cc1F>>CCOC(=O)CCc1ccc(NCc2cccc3c2CCCN3CC(OC)c2ccccc2)cc1F,[Pd],C1CCOC1,,CCO,[H][H],test
US20140051706A1,CC(C)[C@H](N)C(=O)OC(C)(C)C.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)C(N=C=O)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20110257100A1,O=C(c1ccc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)cc1)N1CCCC1>>Nc1ccc(Oc2ccnc3cc(-c4ccc(C(=O)N5CCCC5)cc4)sc23)c(F)c1,[Zn],CO,,[Cl-].[NH4+],,test
US20130316943A1,O=[N+]([O-])c1ccc2c(c1)COB2O>>Nc1ccc2c(c1)COB2O,[Zn],CO,,Cl,,test
US06060207,C=CC(=O)O.CC1CCC(C(C)C)C(O)C1>>C=CC(=O)OC1CC(C)CCC1C(C)C,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040132727A1,COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.O=C(N=C=S)c1ccccc1>>COc1cc2ncnc(Oc3ccc(NC(=S)NC(=O)c4ccccc4)cc3)c2cc1OC,,Cc1ccccc1,,CCO,,test
US04444775,COC(=O)CCCc1ccnc(C#N)c1>>COC(=O)CCCc1ccnc(CN)c1,[Pd],CO,,,,test
US20110092526A1,COC(=O)c1cnc(N[C@H]2CCOC2)nc1C1CCCC1>>O=C(O)c1cnc(N[C@H]2CCOC2)nc1C1CCCC1,,CO,,[Na+].[OH-],,test
US20090275578A1,COC(=O)c1ccccc1CBr.NCCCc1cccc(Cl)c1>>O=C1c2ccccc2CN1CCCc1cccc(Cl)c1,,CCCCCC,Cc1ccccc1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090156600A1,CCc1nc2c(F)ccc(OCC(=O)OC)c2c(OC(F)F)c1Cc1ccc(Cl)cc1F>>CCc1nc2c(F)ccc(OCC(=O)O)c2c(OC(F)F)c1Cc1ccc(Cl)cc1F,,C1CCOC1,,[Li+].[OH-],,test
US20070105838A1,CC(C)N1CCC(Oc2ccc(C(=O)O)c(Cl)c2)CC1.Cl.O=S(Cl)Cl>>CC(C)N1CCC(Oc2ccc(C(=O)Cl)c(Cl)c2)CC1.Cl,,O=S(Cl)Cl,,,,test
US20080176840A1,CCc1nc(C(=O)NN)c(OC)cc1OC.Cn1ccc2cc(N=C=S)ccc21>>CCc1nc(C(=O)NNC(=S)Nc2ccc3c(ccn3C)c2)c(OC)cc1OC,,CCO,,,,test
US20030171403A1,COC(=O)c1ccc(-c2nn(Cc3ccccc3)c3ccccc23)o1>>OCc1ccc(-c2nn(Cc3ccccc3)c3ccccc23)o1,,C1CCOC1,,,,test
US20060100234A1,COC(=O)c1cc(N)c2nc(C)c(C)n2c1.c1ccc2c(c1)CC1OC21>>COC(=O)c1cc(N[C@@H]2c3ccccc3C[C@H]2O)c2nc(C)c(C)n2c1,,C1COCCO1,O,,,test
US04855086,O=C(O)/C=C/CCC#Cc1ccccc1.O=S(Cl)Cl>>O=C(Cl)/C=C/CCC#Cc1ccccc1,,c1ccccc1,,,,test
US04349674,Cc1nc2ccccc2nc1Cl.NC(N)=S>>Cc1nc2ccccc2nc1SC(=N)N.Cl,,CC(C)=O,,C,,test
US20110076292A1,CC(=O)N(C)C.CC(C)n1cncn1>>CC(=O)c1ncnn1C(C)C,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20150299193A1,BrP(Br)Br.OCc1csc(C(F)(F)F)n1>>FC(F)(F)c1nc(CBr)cs1,,ClCCl,,,,test
US06214869B1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1cccc2c1CCO2>>O=S(=O)(Oc1cccc2c1CCO2)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US20090012118A1,O=C(O)c1cc(=O)c2cc(O)ccc2[nH]1.c1ccc(COC2CCNCC2)cc1>>O=C(c1cc(=O)c2cc(O)ccc2[nH]1)N1CCC(OCc2ccccc2)CC1,,CCOCC,,,,test
US20130296480A1,C=C(P(c1ccccc1)c1ccccc1)P(c1ccccc1)c1ccccc1>>C=C(P(c1ccccc1)c1ccccc1)P(c1ccccc1)c1ccccc1,,CCCCCC,,,,test
US20070082912A1,CCOC(=O)c1cccc(N)c1.COc1ccc(COc2ccc(Cl)cc2C(=O)CCC(C)=O)cc1>>CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccc(OC)cc2)c1,,Cc1ccccc1,,,,test
US05324722,CCC1=Nc2cc(Cl)ccc2Oc2ccccc21>>CCC1Nc2cc(Cl)ccc2Oc2ccccc21,,C1CCOC1,,[BH3-]C#N.[Na+],,test
US06037367,COc1ccc(C(C#Cc2ccccc2)CC(=O)COC(C)=O)cc1OC1CCCC1>>COc1ccc(C(C#Cc2ccccc2)CC(=O)CO)cc1OC1CCCC1,,CO,O,[Na+].[OH-],,test
US20080167307A1,Br.CCCCCCI.CCc1cnc(NCCc2csc(SC(C)(C)C(=O)OC(C)(C)C)n2)nc1>>Br.CCCCCCN(CCc1csc(SC(C)(C)C(=O)O)n1)c1ncc(CC)cn1,,CCOCC,,CC(=O)O,,test
US20110195980A1,O=[N+]([O-])c1cnc(Cl)nc1Cl>>Nc1cnc(Cl)nc1Cl,[Fe],CC(=O)O,,,,test
US20130317001A1,CS(N)(=O)=O.O=C(O)c1cc(C2CC2)c(OCC2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1F>>CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1F,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US04863958,CCCc1ccc2oc(Cc3ccc(OC)cc3)c(C)c2c1O.COC(Cl)Cl>>CCCc1ccc2oc(Cc3ccc(OC)c(C=O)c3)c(C)c2c1O,,ClCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20100155257A1,ClCc1ccc(Cl)cc1.NC(=O)c1cccnc1>>NC(=O)c1ccc[n+](Cc2ccc(Cl)cc2)c1.[Cl-],,CCO,CO,,,test
US20150266821A1,Cc1ccc(S(=O)(=O)n2c3c(c4cc(Cl)c(Cl)cc42)CCCC3(O[Si](C)(C)C)C(F)(F)C(F)(F)F)cc1>>OC1(C(F)(F)C(F)(F)F)CCCc2c1[nH]c1cc(Cl)c(Cl)cc21,,C1CCOC1,O,[K+].[OH-],,test
US20120208859A1,COc1cc(F)c([N+](=O)[O-])c(Nc2ccc(I)cc2F)c1F>>COc1cc(F)c(N)c(Nc2ccc(I)cc2F)c1F,,CCO,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20150065705A1,CC(C)(C)OC(=O)N1CCC(Nc2ccc(F)cc2)CC1.CI>>CN(c1ccc(F)cc1)C1CCN(C(=O)OC(C)(C)C)CC1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20060063814A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1C#N)C(=O)O.Fc1nc(F)nc(F)n1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1C#N)C(=O)F,,ClCCl,,c1ccncc1,,test
US20060160857A1,CC(=O)OC(C)=O.Cc1nc([N+](=O)[O-])ccc1O>>CC(=O)Oc1ccc([N+](=O)[O-])nc1C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150376160A1,Cc1cscc1C(C)O>>CC(=O)c1cscc1C,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20090069297A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CSCCOc1cc(Br)ccc1Cl>>CSCCOc1cc(B2OC(C)(C)C(C)(C)O2)ccc1Cl,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20100273767A1,O=C1CC2CNCCN2c2ccccc2N1.O=C1CCC(=O)N1Br>>O=C1CC2CNCCN2c2ccc(Br)cc2N1,,CC(=O)O,O,,,test
US20080096877A1,CON(C)C(=O)CC1CN=C(c2cc3cccc(N(C)S(=O)(=O)c4cccs4)c3[nH]2)S1.C[Mg]Br>>CC(=O)CC1CN=C(c2cc3cccc(N(C)S(=O)(=O)c4cccs4)c3[nH]2)S1,,C1CCOC1,,O=C(O)CC(O)(CC(=O)O)C(=O)O,,test
US06166006,COC(=O)C1=Cc2cc(-c3ccc(C)s3)ccc2OCC1>>Cc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCO3)s1,,C1CCOC1,CO,[Na+].[OH-],,test
US20090275588A1,CCN.O=Cc1ncccc1F>>CCNCc1ncccc1F,,C1CCOC1,,,,test
US20090186891A1,COC(=O)CCc1cc(C)c(-c2nc3ccc(-c4nnc(Nc5cccc(Cl)c5)o4)cc3[nH]2)c(C)c1>>Cc1cc(CCC(=O)O)cc(C)c1-c1nc2ccc(-c3nnc(Nc4cccc(Cl)c4)o3)cc2[nH]1,,CO,,[Na+].[OH-],,test
US20110275608A1,COC(=O)C#CC(=O)OC.Nc1ccccc1>>COC(=O)/C=C(/Nc1ccccc1)C(=O)OC,,CO,,,,test
US20100121048A1,CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)[C@H](CO)C1.N#Cc1ccc(O)cc1>>CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)[C@H](COc2ccc(C#N)cc2)C1,,Cc1ccccc1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04382944,CC(C)(CF)C(=O)C(Oc1ccc(Cl)cc1)n1cncn1>>CC(C)(CF)C(O)C(Oc1ccc(Cl)cc1)n1cncn1,,CO,,Cl,[BH4-].[Na+],test
US20130059835A1,CCOc1c(C(C)=O)cc(Cl)c(C)c1I.CN(C)C(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cn1>>CCOc1c(C(C)=O)cc(Cl)c(C)c1-c1ccc(C(=O)N(C)C)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US05326780,CCOC(=O)Cl.CCc1nc(C)[nH]c1Sc1ccccc1>>CCOCn1c(C)nc(CC)c1Sc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20060089398A1,C=CCOC(=O)c1ccccc1NC(=O)c1c(-c2c(Cl)cccc2Cl)noc1C>>Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)Nc1ccccc1C(=O)O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,ClCCl,,C1COCCN1,,test
US20090312381A1,CCOC(=O)C(C)n1nc(-c2ccc(Cl)cc2)n(C2CC2)c1=O>>CC(C(=O)O)n1nc(-c2ccc(Cl)cc2)n(C2CC2)c1=O,,CO,,[K+].[OH-],,test
US20160016948A1,C[C@H](n1c([C@@H](C)OC2CCCCO2)nc2cnc(Nc3ccnc(N4CC[C@](C)(O)[C@H](F)C4)n3)cc21)C(F)(F)F>>C[C@H](n1c([C@@H](C)O)nc2cnc(Nc3ccnc(N4CC[C@](C)(O)[C@H](F)C4)n3)cc21)C(F)(F)F,,ClCCl,,Cc1ccccc1,O=C(O)C(F)(F)F,test
US20110196153A1,COC(=O)c1cc(F)cc([N+](=O)[O-])c1C(=O)Cc1ncn(C)n1>>Cn1ncnc1/C=C1\OC(=O)c2cc(F)cc([N+](=O)[O-])c21,,CCCCCCC,,C1CCOC1,Cl,test
US20150218172A1,CC(C)(C)N.O=CCc1c(Cl)ncnc1Cl>>CC(C)(C)n1ccc2c(Cl)ncnc21,,CCO,,,,test
US20090131444A1,COc1ccc2nccc(NC(=O)C3CCC(NC(=O)OC(C)(C)C)C(=O)N3)c2n1>>COc1ccc2nccc(NC(=O)C3CCC(N)C(=O)N3)c2n1,,O=C(O)C(F)(F)F,,,,test
US20040142982A1,COC(=O)[C@H](Cc1ccc(Oc2nccc3cnccc23)cc1)NC(=O)OC(C)(C)C>>COC(=O)[C@@H](N)Cc1ccc(Oc2nccc3cnccc23)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050143443A1,CCOC(=O)c1ccc(C(=O)Cc2ccccc2)[nH]1>>CCOC(=O)c1ccc(CCc2ccccc2)[nH]1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20130005707A1,COc1ccc(CNc2cccc(Oc3ccccc3)n2)cc1>>Nc1cccc(Oc2ccccc2)n1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110092505A1,CC(C)N.O=C(O)c1ccc(-c2ccnc(NC3CCCCC3)c2)nc1N1CCNCC1>>CC(C)NC(=O)c1ccc(-c2ccnc(NC3CCCCC3)c2)nc1N1CCNCC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110218192A1,CN1C(=O)C2(CC(C)(C)Oc3ccc(Br)cc32)N=C1N.N#Cc1cccc(B(O)O)c1>>CN1C(=O)C2(CC(C)(C)Oc3ccc(-c4cccc(C#N)c4)cc32)N=C1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1C,,O=C([O-])[O-].[Na+].[Na+],,test
US04957928,Cc1ccc(S(=O)(=O)Cl)cc1.OCCC1CCc2ccccc2O1>>Cc1ccc(S(=O)(=O)OCCC2CCc3ccccc3O2)cc1,,c1ccncc1,,,,test
US20130053409A1,C=CC(=O)Cl.COc1cc(N2CC[C@@H]3CN(C)C[C@@H]32)c(N)cc1Nc1nccc(-c2cnn3ccccc23)n1>>C=CC(=O)Nc1cc(Nc2nccc(-c3cnn4ccccc34)n2)c(OC)cc1N1CC[C@@H]2CN(C)C[C@@H]21,,C1CCOC1,ClCCl,,,test
US20110118245A1,CC(C)Cn1nc(C(C)(C)C)cc1NC(=O)Oc1ccccc1.COc1cc2ncnc(Sc3cccc(N)c3)c2cc1OC>>COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(C(C)(C)C)nn4CC(C)C)c3)c2cc1OC,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20140179666A1,CC[C@H]1CN(Cc2ccccc2)[C@H](C)CN1.O=C(CBr)OCc1ccccc1>>CC[C@H]1CN(Cc2ccccc2)[C@H](C)CN1CC(=O)OCc1ccccc1,,CC#N,ClC(Cl)Cl,O=C([O-])[O-].[K+].[K+],,test
US20060235222A1,CC(C)=NO.COC(=O)c1ccc(C#N)c(F)c1>>COC(=O)c1ccc(C#N)c(ON=C(C)C)c1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US06057369,CC(C)(C)OC(=O)C=CCCCCc1ccccc1>>O=C(O)C=CCCCCc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05990102,CC(=O)OC1CC(=O)N1.COc1ccc(S)cc1OC>>COc1ccc(SC2CC(=O)N2)cc1OC,,CCO,,[Na],,test
US20120283261A1,CN(C)C(=O)c1ccccc1Nc1nc(Cl)ncc1C(F)(F)F.CN1CCN(Cc2ccc(N)cc2)CC1>>CN1CCN(Cc2ccc(Nc3ncc(C(F)(F)F)c(Nc4ccccc4C(=O)N(C)C)n3)cc2)CC1,,CO,ClCCl,,,test
US05925765,CO.ClCc1cnc(Cl)c(Cl)c1>>COCc1cnc(Cl)c(Cl)c1,,CO,,C[O-].[Na+],,test
US20140121198A1,N[C@@H]1CC[C@@H](CO)CC1.O=[N+]([O-])c1cnc2ccsc2c1Cl>>O=[N+]([O-])c1cnc2ccsc2c1N[C@@H]1CC[C@@H](CO)CC1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US04616014,CSc1nnc(-c2ccccc2)c(C)n1.NCCO>>Cc1nc(NCCO)nnc1-c1ccccc1,,CCOC(C)=O,,,,test
US20110190342A1,N[C@@H](Cc1ccc(Oc2ccc(Cl)cn2)cc1)C(=O)O.O=C(O)c1cc2cc(Cl)ccc2nc1Cl>>O=C(O)c1cc2cc(Cl)ccc2nc1N[C@@H](Cc1ccc(Oc2ccc(Cl)cn2)cc1)C(=O)O,,CS(C)=O,,,,test
US20080004275A1,CN(C)C=O.O=C(Cl)CBr.O=C(Nc1ccc(OC(F)(F)F)cc1)Nc1cn(Cc2ccc(C(F)(F)F)cc2)c(C(=O)NCCO)n1>>Cc1cc(OC(F)(F)F)ccc1NC(=O)Nc1cn(Cc2ccc(C(F)(F)F)cc2)c(C(=O)NCCOC(=O)CCl)n1,CN(C)c1ccncc1,CN(C)C=O,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20040014962A1,C=CCOC(=O)c1csc(N2CC(O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)C2)n1>>C=CCOC(=O)c1csc(N2CC(O)C2)n1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06608084B1,COC(=O)[C@H](Cc1ccc2ncccc2c1)NC(=O)OC(C)(C)C>>COC(=O)C(Cc1ccc2c(c1)CCCN2)NC(=O)OC(C)(C)C,[Pd],CCO,,O=C[O-].[NH4+],,test
US20050277652A1,C1CCOC1.CCN(CC)CC.Nc1cc(Oc2ccc(NC(=S)NC(=O)Cc3ccccc3)c(F)c2)ccn1.O=C(Cl)Oc1ccccc1>>O=C(Cc1ccccc1)NC(=S)Nc1ccc(Oc2ccnc(NC(=O)N3CCCCC3)c2)cc1F,,CCOCC,,,,test
US20030186969A1,C1CCNC1.O=Cc1ccc(C(=O)O)cc1>>O=Cc1ccc(C(=O)N2CCCC2)cc1,,ClCCl,,CCN(CC)CC,,test
US20060142265A1,CN.O=Cc1sc2cccc(F)c2c1Cl>>CNCc1sc2cccc(F)c2c1Cl,,CO,,[BH4-].[Na+],,test
US20100158818A1,CC(C)(C)OCl.CC(C)(N)CC[N+]1(C)CCC(C)(C)CC1.Cl.[Cl-]>>CC1(C)CC[N+](C)(CCC(C)(C)N(Cl)Cl)CC1.[Cl-],,CO,O,,,test
US20160145267A1,CC(C)(C)OC(=O)CBr.CCOc1cc(F)c(Cn2nc(-c3nc(N)c(O)c(N)n3)c(C)c2C2CC2)c(F)c1>>CCOc1cc(F)c(Cn2nc(-c3nc(N)c(OCC(=O)OC(C)(C)C)c(N)n3)c(C)c2C2CC2)c(F)c1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US06498179B1,Cc1nccn1-c1nc(-c2ccc(Cl)cc2)c(CCC(=O)NCCCl)o1>>Cc1nccn1-c1nc(-c2ccc(Cl)cc2)c(CCC2=NCCO2)o1,,CN(C)C=O,,[H-].[Na+],,test
US20110182850A1,C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@]2(CN1C(=O)[C@@H](NC(=O)[C@@H](N)C1CCCCC1)C(C)(C)C)C(C)(C)C21CCC1)C(=O)NS(=O)(=O)C1(CCC)CC1.CCN1CCCC[C@H]1C(=O)O>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@]2(CN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCCN1CC)C1CCCCC1)C(C)(C)C)C(C)(C)C21CCC1)C(=O)NS(=O)(=O)C1(CCC)CC1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120115813A1,COc1ccc(C=O)c(B2OC(C)(C)C(C)(C)O2)c1OCCCOCc1ccccc1.C[N+](=O)[O-]>>COc1ccc2c(c1OCCCOCc1ccccc1)B(O)OC2C[N+](=O)[O-],,O,,C1CCOC1,[Na+].[OH-],test
US20070037807A1,CCOC(=O)CS.Cc1ccc(-c2c(COS(C)(=O)=O)c(C)nc(CC(C)C)c2CNC(=O)OC(C)(C)C)cc1>>Cc1ccc(-c2c(CSCC(=O)O)c(C)nc(CC(C)C)c2CNC(=O)OC(C)(C)C)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160002248A1,Nc1nnc(CCCCc2cc3cc(Cc4ccccc4)[nH]c3nn2)s1.O=C(O)[C@@H](O)c1ccccc1>>O=C(Nc1nnc(CCCCc2cc3cc(Cc4ccccc4)[nH]c3nn2)s1)[C@@H](O)c1ccccc1,,CN(C)C=O,,,,test
US04886803,CCOC(=O)c1nc2cc(OC)c(OC)cc2n1S(=O)(=O)N(C)C.Cc1cc(C)nc(N)c1>>COc1cc2nc(C(=O)Nc3cc(C)cc(C)n3)n(S(=O)(=O)N(C)C)c2cc1OC,,CS(C)=O,,[H-].[Na+],[Cl-].[NH4+],test
US20110077240A1,O=[N+]([O-])c1ccc(Oc2ccnc3cc(-c4ccc(CN5CCOCC5)cn4)sc23)c(F)c1>>Nc1ccc(Oc2ccnc3cc(-c4ccc(CN5CCOCC5)cn4)sc23)c(F)c1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20120202785A1,O=[N+]([O-])c1ccccc1NC1CCCOC1>>Nc1ccccc1NC1CCCOC1,[Pd],CCOC(C)=O,,,,test
US04670045,CCOC(=O)Cl.Oc1cc(C(Cl)(Cl)Cl)cc(Cl)n1>>CCOC(=O)Oc1cc(C(Cl)(Cl)Cl)cc(Cl)n1,,Cc1ccccc1,,CCN(CC)CC,,test
US20140094462A1,C=CC[C@@H](C)O.CC(C)(C)OC(=O)N[C@@H](CC(=O)O)c1ccccc1>>C=CC[C@H](C)OC(=O)C[C@@H](NC(=O)OC(C)(C)C)c1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20140329929A1,c1coc(COCCCCCCCCCCCOC2CCCCO2)c1>>OCCCCCCCCCCCOCc1ccco1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05585394,COc1cc([N+](=O)[O-])ccc1S(=O)(=O)Cl.O=c1[nH]c2ccc(Cl)cc2n1-c1ccccc1>>COc1cc([N+](=O)[O-])ccc1S(=O)(=O)n1c(=O)n(-c2ccccc2)c2cc(Cl)ccc21,,CN(C)C=O,,O,[H-].[Na+],test
US05840732,CCCC=C1SC(=O)N(CCCCOc2cccc3nccn23)C1=O.Cl>>CCCC=C1SC(=O)N(CCCCOc2cccc3nccn23)C1=O.Cl,,CO,,,,test
US20080227791A1,Cc1ccc(S(=O)(=O)OC2CCN(C(=O)OC(C)(C)C)CC2)cc1.Nc1nnc(C(F)(F)F)cc1Cl>>CC(C)(C)OC(=O)N1CCC(Nc2nnc(C(F)(F)F)cc2Cl)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20140171412A1,Cn1c(=O)c2c(-c3ccccc3)n(CCOCC(=O)c3nc(Cl)cs3)cc2n(C)c1=O>>Cn1c(=O)c2c(-c3ccccc3)n(CCOCC(O)c3nc(Cl)cs3)cc2n(C)c1=O,,CO,,[BH4-].[Na+],,test
US20050215610A1,CCCC(NC1CCc2cc(F)cc(F)c2C1)C(=O)OC>>CCCC(NC1CCc2cc(F)cc(F)c2C1)C(=O)O,,C1CCOC1,O,[Li+].[OH-],,test
US20100317647A1,COC(=O)C1CCC(O)C1.CS(=O)(=O)Cl>>COC(=O)C1CCC(OS(C)(=O)=O)C1,,ClCCl,,CCN(CC)CC,,test
US20070232632A1,CCOC(=O)Cl.CS(=N)(=O)c1ccc([N+](=O)[O-])cc1>>CCOC(=O)N=S(C)(=O)c1ccc([N+](=O)[O-])cc1,,c1ccncc1,,[Cl-].[Na+],,test
US20080200464A1,Cc1cnc(Nc2ccc(O)c(F)c2)c(C(=O)Nc2ccccc2)c1.Nc1cc(Cl)ccn1>>Cc1cnc(Nc2ccc(Oc3ccnc(N)c3)c(F)c2)c(C(=O)Nc2ccccc2)c1,CN(C)c1ccncc1,CN1CCCC1=O,,CCN(CC)CC,,test
US20040192767A1,COC(=O)c1cc(CNc2ccc(-c3ccc(OC)cn3)cc2)c(C)o1.Cl>>COc1ccc(-c2ccc(NCc3cc(C(=O)O)oc3C)cc2)nc1.Cl,,C1CCOC1,,O=C(O)C(F)(F)F,,test
US04312870,CCOC(=O)CC(=O)OCC.NNc1ccc(Cl)cc1>>O=C1CC(=O)N(c2ccc(Cl)cc2)N1,,CCO,,[Na],,test
US04994482,COC(=O)CSCCCCCCn1nc(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1>>O=C(O)CSCCCCCCn1nc(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1,,CO,,[Na+].[OH-],,test
US20130261116A1,Cl.NC(=O)c1c(F)cc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)cc1F>>Cl.NC(=O)c1c(F)cc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)cc1F,,C1CCOC1,,CCOCC,,test
US20080113946A1,COc1cc(N)cc(N(C)C)c1.O=C(OCC1c2ccccc2-c2ccccc21)N1Cc2nc(Cl)nc(Cl)c2C1>>COc1cc(Nc2nc(Cl)nc3c2CN(C(=O)OCC2c4ccccc4-c4ccccc42)C3)cc(N(C)C)c1,Cl,CC(C)O,,,,test
US20160046597A1,N#Cc1cccc(C(=O)Nc2ccc3[nH]cc(C4CCNCC4)c3c2)c1.O=C=NC1CCCC1>>N#Cc1cccc(C(=O)Nc2ccc3[nH]cc(C4CCN(C(=O)NC5CCCC5)CC4)c3c2)c1,,CN(C)C=O,,CCN(CC)CC,,test
US06294503B1,O=C1COc2cc(F)c(-n3c(=O)cc(C(F)(F)F)[nH]c3=O)cc2N1.O=[N+]([O-])O>>O=C1COc2cc(F)c(-n3c(=O)cc(C(F)(F)F)[nH]c3=O)c([N+](=O)[O-])c2N1,,CC(=O)O,,,,test
US20140163025A1,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5ccc(-c6cc(C)nc(C)c6)cc5F)ccc(F)c43)ccc21>>Cc1cc(-c2ccc(Oc3ccc(F)c4c3CC[C@H]4Oc3ccc4c(c3)OC[C@H]4CC(=O)O)c(F)c2)cc(C)n1,,CCO,,[K+].[OH-],,test
US04435394,CN(C)S(=O)(=O)Nc1cccc(C(=O)c2ccccc2)c1.NN>>CN(C)S(=O)(=O)Nc1cccc(C(=NN)c2ccccc2)c1,,CCO,,O,,test
US20020045751A1,Cc1cc([N+](=O)[O-])cc(C)c1Cl.O=S(=O)(c1ccc(F)cc1)c1cc(O)ccc1O>>Cc1cc([N+](=O)[O-])cc(C)c1Oc1ccc(O)c(S(=O)(=O)c2ccc(F)cc2)c1,,CN1CCCC1=O,,[H-].[Na+],,test
US20090143361A1,COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)cc(Cl)c4)n3c2n1.OB(O)c1cccc(C(F)(F)F)c1>>COc1ccc2nc(C)c3c(C)nc(-c4cccc(C(F)(F)F)c4)n3c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20130225524A1,CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(Br)ccc23)c1.COc1cc(B2OC(C)(C)C(C)(C)O2)cc(C(F)(F)F)n1>>CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(-c4cc(OC)nc(C(F)(F)F)c4)ccc23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,,,test
US20160031871A1,CC(C)(C)OC(=O)N1CCNCC1.CC(Cl)c1ccc2c(c1)OCO2>>CC(c1ccc2c(c1)OCO2)N1CCN(C(=O)OC(C)(C)C)CC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20090247547A1,COC(=O)/C=C/c1ccc(C2CCCN2CCc2c(C(C)(C)C)[nH]c3cc([N+](=O)[O-])ccc23)cc1>>COC(=O)/C=C/c1ccc(C2CCCN2CCc2c(C(C)(C)C)[nH]c3cc(N)ccc23)cc1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20150291595A1,COc1cc(NC(=O)c2c(N)ncnc2N[C@@H](C)c2nn3ccc(C)c3c(=O)n2-c2ccccc2)cc(OC)c1>>Cc1ccn2nc([C@H](C)Nc3ncnc(N)c3C(=O)Nc3cc(O)cc(O)c3)n(-c3ccccc3)c(=O)c12,,ClCCl,,BrB(Br)Br,,test
US20070265272A1,CC(C)(C)OC(=O)N[C@@H]1CCN(c2cnc3nnn(Cc4ccc5ncccc5c4)c3n2)C1.CI>>CN(C(=O)OC(C)(C)C)[C@@H]1CCN(c2cnc3nnn(Cc4ccc5ncccc5c4)c3n2)C1,,C1CCOC1,,[H-].[Na+],,test
US20110118283A1,N#CCc1ncc(Cl)cc1F.O=Cc1cccc(Cl)c1F>>N#C/C(=C\c1cccc(Cl)c1F)c1ncc(Cl)cc1F,,CO,,C[O-].[Na+],,test
US20030109538A1,CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nc(S(C)(=O)=O)n2)cc1.N>>CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nc(N)n2)cc1,,CC#N,,,,test
US20030181359A1,BrCc1ccccc1.CSCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)O>>CSCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)OCc1ccccc1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US04933355,Cc1ccccc1Nc1nc(CO)cs1>>Cc1ccccc1Nc1nc(C=O)cs1,,CS(C)=O,,CCN(CC)CC,,test
US20140107097A1,CON(C)C(=O)c1csc(C)n1.Cn1cncc1Br>>Cc1nc(C(=O)c2cncn2C)cs1,,C1CCOC1,,,,test
US20040192623A1,CC[C@H](C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)Oc1c(F)c(F)c(F)c(F)c1F>>CC[C@H](C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O,,C1CCOC1,,,,test
US05244907,CNc1cc(OC)c(C(=O)O)cc1Cl.NCC12CCCN(CCC1)C2>>CNc1cc(OC)c(C(=O)NCC23CCCN(CCC2)C3)cc1Cl,,C1CCOC1,CO,O=C(n1ccnc1)n1ccnc1,,test
US20080312256A1,Nc1nncs1.O=C(Cl)C(CC1CCCC1)c1ccccc1>>O=C(Nc1nncs1)C(CC1CCCC1)c1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090170855A1,ClCCN1CCOCC1.O=c1c2ccccc2c2nc3ccc(O)cn3c2n1-c1ccc([N+](=O)[O-])cc1>>O=c1c2ccccc2c2nc3ccc(OCCN4CCOCC4)cn3c2n1-c1ccc([N+](=O)[O-])cc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20020156081A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COc1cc(Br)ccc1N(C)C(=O)CCc1ccccc1>>COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1N(C)C(=O)CCc1ccccc1,,CN(C)C=O,,ClCCl,CC(=O)[O-].[K+],test
US20100041041A1,O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1COCc1ccccc1>>Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O,[Pd],CCO,,,,test
US20070232627A1,CC(C)(C)c1cnc(NC(=O)c2ccc(Cl)c([N+](=O)[O-])c2)s1.Nc1ccc(S)cc1>>CC(C)(C)c1cnc(NC(=O)c2ccc(Sc3ccc(N)cc3)c([N+](=O)[O-])c2)s1,,CCO,,CC(=O)[O-].[Na+],,test
US05348978,CCOC(=O)[C@H](CCO)OC(C)=O.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOC(=O)[C@H](CCOS(=O)(=O)c1ccc(C)cc1)OC(C)=O,,c1ccncc1,,CCOC(C)=O,O,test
US20020058681A1,CC(=O)Nc1ccc(S(N)(=O)=O)nc1>>Nc1ccc(S(N)(=O)=O)nc1,,[Na+],[OH-],,,test
US20150361068A1,CC(=O)O.C[C@H](Nc1ncnc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1CCCN>>CC(=O)NCCCn1c([C@H](C)Nc2ncnc(N)c2C#N)nc2cccc(Cl)c2c1=O,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090186911A1,CCOC(=O)N=S(=O)(CC)c1cccc(COc2cc3ncnc(Nc4nccs4)c3cc2OC)c1>>CCS(=N)(=O)c1cccc(COc2cc3ncnc(Nc4nccs4)c3cc2OC)c1,,CO,,ClCCl,,test
US20150191461A1,BrBr.C=CCCNC(=O)OCc1ccccc1>>O=C1NCCC(CBr)O1,,ClCCl,O,,,test
US20100087432A1,COC(=O)Cn1cc(C#N)c(-c2cc([N+](=O)[O-])cc(C(F)(F)F)c2)c1>>COC(=O)Cn1cc(C#N)c(-c2cc(N)cc(C(F)(F)F)c2)c1,[Fe],CC(=O)O,CCO,,,test
US20160137653A1,Cc1cc(C2CCC(C(C)N)CC2)ccn1.O=C(O)c1ccc(Cl)cc1>>Cc1cc(C2CCC(C(C)NC(=O)c3ccc(Cl)cc3)CC2)ccn1,,C1CCOC1,,ClCCCl,On1nnc2ccccc21,test
US20060025350A1,C=CCOC1O[C@H](COCc2ccccc2)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1.Cc1ccc(S(=O)(=O)Cl)cc1.c1ccncc1>>C=CCOC1O[C@H](COCc2ccccc2)[C@@H](O[C@@H]2O[C@H](C(O)S(=O)(=O)c3ccccc3C)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,CN(C)c1ccncc1,,,,,test
US04127720,CCOC(=O)c1cnc2c3ccccc3ccn2c1=O>>CCOC(=O)c1cnc2n(c1=O)CCc1ccccc1-2,[Pd],CC(=O)O,,[H][H],,test
US20070049581A1,CC(C)(C)OC(=O)N1CCN(C2CCNCC2)CC1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)N1CCN(C2CCN(C(=O)OCc3ccccc3)CC2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150344466A1,CC(=O)CCCc1cccc(F)c1.CCOC(=O)C(=O)OCC>>CCOC(=O)C(=O)CC(=O)CCCc1cccc(F)c1,,CCO,,C,C[O-].[Na+],test
US04122090,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.COC(=O)[C@@H](N)C(C)C>>COC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C,,ClC(Cl)Cl,,Cl,c1ccncc1,test
US20050085458A1,Cc1ccc2c(OCCN3CCC(=Cc4ccc5c(c4)NC(=O)C5)CC3)cccc2n1>>Cc1ccc2c(OCCN3CCC(Cc4ccc5c(c4)NC(=O)C5)CC3)cccc2n1,[Pd],C1CCOC1,CO,O=C[O-].[NH4+],,test
US05248793,CC(C)(C)OC(=O)C[C@H]1C[C@@H](CO)OC(C)(C)O1.O=S(=O)(Cl)c1ccc(Br)cc1>>CC(C)(C)OC(=O)C[C@H]1C[C@@H](COS(=O)(=O)c2ccc(Br)cc2)OC(C)(C)O1,,ClCCl,,CCN(CC)CC,O,test
US20090105257A1,CC(C)c1nc(-c2ccc(C(F)(F)F)cc2)sc1CO.Nc1ccc([C@@H]2C[C@H]2C(=O)O)cc1>>CC(C)c1nc(-c2ccc(C(F)(F)F)cc2)sc1CNc1ccc([C@@H]2C[C@H]2C(=O)O)cc1,,ClCCl,O,CCN(CC)CC,CS(=O)(=O)Cl,test
US08071776B2,CC(=O)SCC(=O)NC1CC1.CSc1nc(Cl)c(C#N)c(C)c1Cl>>CSc1nc2sc(C(=O)NC3CC3)c(N)c2c(C)c1Cl,,CCCCCC,CCOC(C)=O,CO,C[O-].[Na+],test
US20120202988A1,CC12CCC(CC1=O)C2(C)C.CCO.CCOC(OCC)OCC>>CCOC1(OCC)CC2CCC1(C)C2(C)C,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04942143,CCCCCCn1c(=O)c2c(ncn2C)n(C)c1=O>>CCCCCCNC(=O)c1c(NC)ncn1C,,CCO,ClC(Cl)Cl,[Na+].[OH-],,test
US20120309739A1,COCCN.Cn1c(S(C)(=O)=O)nc2oc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)c2c1=O>>COCCNc1nc2oc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)c2c(=O)n1C,,C1CCOC1,,,,test
US07141598B2,Fc1ccc(-c2cccc(Br)c2)cc1.O=C1CCn2cncc21>>OC1(c2cccc(-c3ccc(F)cc3)c2)CCn2cncc21,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US06514985B1,O=[N+]([O-])O.Oc1cc2nnnn2c2ncccc12>>O=[N+]([O-])c1c(O)c2cccnc2n2nnnc12,,CC(=O)O,,O,CC(=O)[O-].[Na+],test
US20100197683A1,CCCCc1c(Cc2c(F)cc(-c3ccccc3C#N)cc2F)c(=O)[nH]c2ncnn12.COCCl>>CCCCc1c(Cc2c(F)cc(-c3ccccc3C#N)cc2F)c(=O)n(COC)c2ncnn12,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20120149676A1,CC(C)(C)C(=O)NCc1ccc(Cl)c(N=C=S)c1Cl.CNc1c(N)cc(C(=O)N[C@@H]2CC[C@@H](C(F)(F)F)CC2)c(N2CC3CC3C2)c1C>>Cc1c(N2CC3CC3C2)c(C(=O)N[C@@H]2CC[C@@H](C(F)(F)F)CC2)cc2nc(Nc3c(Cl)ccc(CNC(=O)C(C)(C)C)c3Cl)n(C)c12,,C1COCCO1,,CC(C)N=C=NC(C)C,,test
US20160221994A1,CC1OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Nc1ccc(/C=C/C(=O)NCC2Cc3cc(Br)cc(Cl)c3O2)cn1>>CC1(C)OB(c2cc(Cl)c3c(c2)CC(CNC(=O)/C=C/c2ccc(N)nc2)O3)OC1(C)C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,CC(=O)[O-].[K+],,test
US07074787B2,O=C(Cl)Cl.OCCNc1cc(-c2ccnc(Nc3cccc(Cl)c3)n2)ccn1>>O=C1OCCN1c1cc(-c2ccnc(Nc3cccc(Cl)c3)n2)ccn1,,C1CCOC1,Cc1ccccc1,CCN(CC)CC,,test
US20110039852A1,COC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2C=O)c1.NCCc1ccccc1>>COC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CNCCc2ccccc2)c1,CC(=O)O,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05310735,COc1ccc(CS[C@H]2C[C@@H](C(=O)N3CCN(C)CC3)N(C(=O)OCc3ccc([N+](=O)[O-])cc3)C2)cc1.O=S(=O)(O)C(F)(F)F>>CN1CCN(C(=O)[C@@H]2C[C@H](S)CN2C(=O)OCc2ccc([N+](=O)[O-])cc2)CC1.O=S(=O)(O)C(F)(F)F,,COc1ccccc1,,O=C(O)C(F)(F)F,,test
US20090239861A1,O=[N+]([O-])c1ccc2c(ccn2Cc2nccs2)c1>>Nc1ccc2c(ccn2Cc2nccs2)c1,O=[Pt]=O,CO,,,,test
US06881736B1,CCOC(=O)C=C(Cc1ccc(OCc2ccccc2)cc1)c1cccnc1>>CCOC(=O)CC(Cc1ccc(O)cc1)c1cccnc1,[Pd],CCO,,,,test
US20100331326A1,CC(=O)Nc1ccncc1N1CCN(c2ccc3ncsc3c2)C1=O.Cl>>Cl.Nc1ccncc1N1CCN(c2ccc3ncsc3c2)C1=O,,CCO,ClC(Cl)Cl,CO,,test
US20080280945A1,COc1c(OS(C)(=O)=O)nc(C(=O)N(C)C[C@H](OC2CCCCO2)C(C)(C)COS(C)(=O)=O)c2c1C(=O)N(Cc1ccc(F)c(Cl)c1)CC2>>COc1c2c(c3n(c1=O)CC(C)(C)[C@@H](OC1CCCCO1)CN(C)C3=O)CCN(Cc1ccc(F)c(Cl)c1)C2=O,,CC(=O)N(C)C,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20130131035A1,CNC(=O)c1cccc(N)c1.Fc1cnc(Cl)nc1Cl>>CNC(=O)c1cccc(Nc2nc(Cl)ncc2F)c1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20160181542A1,CC(=O)c1ccc2ccccc2c1O.CN(C)c1ccncc1.Cc1cccc(C)n1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=S(=O)(Oc1cccc2c3ccccc3c3ccccc3c12)C(F)(F)F,CN(C)c1ccncc1,ClCCl,,,,test
US20100168110A1,CCc1nn(CC(=O)NN)c(CC)c1Cc1cc(C)c(OC)c2c1CCC2.O=C(c1ncc[nH]1)c1ncc[nH]1>>CCc1nn(Cc2n[nH]c(=O)o2)c(CC)c1Cc1cc(C)c(OC)c2c1CCC2,,C1COCCO1,,O,,test
US20100087506A1,CC[C@]1(O)CCN(C(=O)OCc2ccccc2)[C@H]1C>>CC[C@]1(O)CCN[C@H]1C,[Pd],O,,,,test
US20100130464A1,Cc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1-c1ccc(C(=CN(C)C(C)c2ccccc2)c2ccc(Cl)cc2)cn1>>CNCC(c1ccccc1)c1ccc(-c2cn[nH]c2)nc1,[Pd],CCO,,[H][H],,test
US20160075663A1,C[C@H](C(=O)Nc1nc2ccc(C#N)cc2n1C1CCC1)[C@@](C)(O[Si](C)(C)C(C)(C)C)c1ccccc1>>C[C@H](C(=O)Nc1nc2ccc(C#N)cc2n1C1CCC1)[C@@](C)(O)c1ccccc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140107251A1,C=C(C)C(=O)OCCO.CC(Cl)OC(=O)Cl.CCOCC>>C=C(C)C(=O)OCCO.CC(Cl)OC(=O)[O-],,CCOCC,,c1ccncc1,,test
US20080108814A1,OCCN(CCc1cccc(F)c1)Cc1ccccc1>>OCCNCCc1cccc(F)c1,[Pd],CO,,,,test
US20090298815A1,CC(C)(C)OC(=O)N1CCC(c2nc(-c3cccc(N)c3F)c(-c3ccnc(Cl)n3)s2)CC1.O=S(=O)(Cl)c1c(F)cccc1F>>CC(C)(C)OC(=O)N1CCC(c2nc(-c3cccc(NS(=O)(=O)c4c(F)cccc4F)c3F)c(-c3ccnc(Cl)n3)s2)CC1,,c1ccncc1,,,,test
US20030069271A1,CCCc1c(Br)c2cc(Cl)ccc2[nH]c1=O.SC1CCCCC1>>CCCc1c(SC2CCCCC2)c2cc(Cl)ccc2[nH]c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20120214803A1,Nc1ccc(Cl)c2cccnc12.O=[N+]([O-])c1cc(F)c(F)cc1S(=O)(=O)Cl>>O=[N+]([O-])c1cc(F)c(F)cc1S(=O)(=O)Nc1ccc(Cl)c2cccnc12,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20120258973A1,COC(=O)CN.Cn1nc(-c2ccccc2)c2c(C(F)(F)F)cc(Br)nc21>>COC(=O)CNc1cc(C(F)(F)F)c2c(-c3ccccc3)nn(C)c2n1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20160075692A1,Cc1cnc(Br)nc1.O=C1NCCN1c1cccc2c1cnn2-c1ccccc1F>>Cc1cnc(N2CCN(c3cccc4c3cnn4-c3ccccc3F)C2=O)nc1,,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20060247266A1,CC(C)(C)C(=O)OC(=O)C(C)(C)C.OCCN1CCCC(N2CCc3cncc4cccc2c34)C1>>CC(C)(C)C(=O)OCCN1CCCC(N2CCc3cncc4cccc2c34)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090143448A1,CCc1sc(N)nc1-c1ccccc1.Cc1cc(S(N)(=O)=O)cs1.O=C(Cl)Oc1ccccc1>>CCc1sc(NC(=O)NS(=O)(=O)c2csc(C)c2)nc1-c1ccccc1,,CC#N,,CCN(CC)CC,,test
US05126448,CCOC(=O)C1=C2C=CN=C3C=CC=CC32SC1.N>>NC(=O)C1=C2C=CN=C3C=CC=CC32SC1,,CCO,,,,test
US05461036,OCCCCCCCCCCCCBr>>O=CCCCCCCCCCCCBr,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US05459137,CC1=NN=C(c2ccc(N)cc2)c2cc3c(cc2C1)OCO3.CN=C=O>>CNC(=O)Nc1ccc(C2=NN=C(C)Cc3cc4c(cc32)OCO4)cc1,,CN(C)C=O,O,,,test
US20080287479A1,CC(C)(C)C1CCC(C(=O)CCl)CC1.CS(=O)(=O)c1ccc2c(c1)[nH]c(=O)n2C1CCNCC1>>CC(C)(C)C1CCC(C(=O)CN2CCC(n3c(=O)[nH]c4cc(S(C)(=O)=O)ccc43)CC2)CC1,,CN(C)C=O,O,O=C(O)C(F)(F)F,,test
US20140378540A1,CC(=O)c1ccc(O)cc1.O=[N+]([O-])c1ccc(F)cc1>>CC(=O)c1ccc(Oc2ccc([N+](=O)[O-])cc2)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20090281092A1,CCOC(=O)C(C)(F)CN(c1nc(Cl)ncc1[N+](=O)[O-])C1CCCC1>>CC1(F)CN(C2CCCC2)c2nc(Cl)ncc2NC1=O,,CC(=O)O,,Cl,,test
US20090209532A1,COc1cc2c(Cl)c(C(=O)N3CCOCC3)sc2c(C#N)c1OC>>N#Cc1c(O)c(O)cc2c(Cl)c(C(=O)N3CCOCC3)sc12,,ClCCl,,BrB(Br)Br,,test
US04616014,CNC(=O)NNc1nnc(-c2ccccc2)c(C)n1>>CNC(=O)NNC1=NC(C)C(c2ccccc2)=NN1,,CO,,[BH4-].[Na+],,test
US06060432,CCN(CC)S(F)(F)F.O=C1C2CC(O)CCN2C(=O)N1c1cc(NS(=O)(=O)CCl)c(Cl)cc1F>>O=C1[C@@H]2C[C@@H](F)CCN2C(=O)N1c1cc(NS(=O)(=O)CCl)c(Cl)cc1F,,ClCCl,,,,test
US05430027,ClCCc1ccccc1.O=C1c2ccccc2C(=O)N1O>>O=C1c2ccccc2C(=O)N1OCCc1ccccc1,,CS(C)=O,,CC(=O)[O-].[Na+],,test
US20050245741A1,Cc1nc2ccc(O)cc2o1.O=C(Cl)c1ccccc1>>Cc1nc2ccc(OC(=O)c3ccccc3)cc2o1,,ClCCl,,CCN(CC)CC,,test
US20080176926A1,Cc1cc(C=O)cc(C)c1Br.OCCCO>>Cc1cc(C2OCCCO2)cc(C)c1Br,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080319043A1,CCOC(=O)C(=O)c1ccccc1.Cc1ccc(OCc2ccccc2)c(Br)c1>>CCOC(=O)C(O)(c1ccccc1)c1cc(C)ccc1OCc1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US20050256201A1,Cl.NC(=O)c1cccc(COCCOc2ccc(CCNC[C@H](O)c3ccc(O)c(CO)c3)cc2)c1>>Cl.NC(=O)c1cccc(COCCOc2ccc(CCNC[C@H](O)c3ccc(O)c(CO)c3)cc2)c1,,CC(C)O,,,,test
US05912246,COc1ccc(N2CCNCC2)cc1.O=C(O)c1cn2cc(Cl)ccc2n1>>COc1ccc(N2CCN(C(=O)c3cn4cc(Cl)ccc4n3)CC2)cc1,,CN(C)C=O,ClCCl,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20040058918A1,COC(=O)C(=Cc1ccncc1)c1ccc(Cl)cc1.NN>>O=C1NNC(c2ccncc2)C1c1ccc(Cl)cc1,,CCO,,,,test
US20100069367A1,CCOC(=O)c1cn(-c2ccc(-c3cccc(S(C)(=O)=O)c3)cc2Cl)c(-c2ccccc2Cl)n1>>CS(=O)(=O)c1cccc(-c2ccc(-n3cc(CO)nc3-c3ccccc3Cl)c(Cl)c2)c1,,ClCCl,,CC(C)C[Al+]CC(C)C.[H-],,test
US20060264460A1,N#Cc1cnc2ccc(Br)cc2c1Nc1ccc(F)c(Cl)c1.NC(=O)c1ccccc1>>N#Cc1cnc2ccc(NC(=O)c3ccccc3)cc2c1Nc1ccc(F)c(Cl)c1,,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20100331326A1,Brc1ccc2ncccc2c1.Cc1ccncc1N1CCNC1=O>>Cc1ccncc1N1CCN(c2ccc3ncccc3c2)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=C([O-])[O-].[K+].[K+],test
US20160214971A1,COc1cc(C(=O)NS(C)(=O)=O)ccc1-c1cnc(F)c(Cl)c1.Oc1cc(Cl)cc(Cl)c1>>COc1cc(C(=O)NS(C)(=O)=O)ccc1-c1cnc(Oc2cc(Cl)cc(Cl)c2)c(Cl)c1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100113458A1,CCN(CC)c1ccc(N)cc1.COc1ccc(CN(c2cc(Cl)nn3c(C#N)cnc23)C2CC2)cc1>>CCN(CC)c1ccc(Nc2cc(N(Cc3ccc(OC)cc3)C3CC3)c3ncc(C#N)n3n2)cc1,,CO,,CN1CCCC1=O,,test
US04820727,CC(C)(C)OC(=O)CBr.CCOC(=O)NC(=O)c1c(F)ccc2c(C(F)(F)F)c(OC)ccc12>>CCOC(=O)N(CC(=O)OC(C)(C)C)C(=O)c1c(F)ccc2c(C(F)(F)F)c(OC)ccc12,,C1CCOC1,,[H-].[Na+],,test
US20080009530A1,CCCCCS(N)(=O)=O.CN(C)C=O.COCCOc1ccc(CO)c(Oc2ncc(C(F)(F)F)cc2Cl)c1>>CCCCCS(=O)(=O)NC(=O)OCc1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl,CN(C)c1ccncc1,CCOC(C)=O,,C1CCC2=NCCCN2CC1,Cl,test
US20100298557A1,COc1ccc(CO)c(OC)c1.CS(=O)(=O)c1n[nH]c2nc(Cl)nc(NC3CC3)c12>>COc1ccc(Cn2nc(S(C)(=O)=O)c3c(NC4CC4)nc(Cl)nc32)c(OC)c1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040214953A1,CCCCCCCC/C=C\CCCCCCCCN(C)CCCCCCCC/C=C\CCCCCCCC.Cl>>CCCCCCCC/C=C\CCCCCCCCN(C)CCCCCCCC/C=C\CCCCCCCC.Cl,,CCO,,O,,test
US20140024666A1,CC(C)(C)c1ccc(CN(Cc2ccc(C(C)(C)C)cc2)C(N)=O)cc1.O=C(Cl)CC(=O)Cl>>CC(C)(C)c1ccc(CN2C(=O)CC(=O)N(Cc3ccc(C(C)(C)C)cc3)C2=O)cc1,,ClCCl,,,,test
US20060167004A1,CCN(CC)C(=O)c1ccc(I)cc1.COC(=O)c1cccc(C=O)c1>>CCN(CC)C(=O)c1ccc(C(O)c2cccc(C(=O)OC)c2)cc1,,C1CCOC1,Cc1ccccc1,[Li]CCCC,[Cl-].[NH4+],test
US20130237535A1,NCC(F)(F)F.O=S(=O)(c1ccc(Br)cc1)N1CCC2(CC1)CO2>>O=S(=O)(c1ccc(Br)cc1)N1CCC(O)(CNCC(F)(F)F)CC1,,CCO,,[Al],,test
US20040260084A1,CC(=O)NC1S[C@@H]2[C@H](c3ccccc3)C(=O)N2C(C(=O)OC(c2ccccc2)c2ccccc2)=C1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(=O)NC1S[C@@H]2[C@H](c3ccccc3)C(=O)N2C(C(=O)OC(c2ccccc2)c2ccccc2)=C1OS(=O)(=O)C(F)(F)F,,ClCCl,,,,test
US20060189666A1,O=S(Cl)Cl.OCc1ncc(-c2ccc(F)cc2)o1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>Fc1ccc(-c2cnc(C[P+](c3ccccc3)(c3ccccc3)c3ccccc3)o2)cc1.[Cl-],,ClCCl,,CCN(CC)CC,O=C([O-])[O-].[Na+].[Na+],test
US04349552,O=C=NCC12CC3CC(CC(C3)C1)C2.O=c1[nH]cc(F)c(=O)[nH]1>>O=C(NCC12CC3CC(CC(C3)C1)C2)n1cc(F)c(=O)[nH]c1=O,,CC(=O)N(C)C,CCOC(C)=O,,,test
US20110288293A1,NCCc1ccc(Cl)cc1.O=S(=O)(Cl)c1ccc(CBr)cc1>>O=S(=O)(NCCc1ccc(Cl)cc1)c1ccc(CBr)cc1,,C1CCOC1,,CCN(CC)CC,CCOC(C)=O,test
US20010053851A1,C#Cc1ccc(C(CC2CCCC2)C(=O)O)cc1.Nc1nccs1>>C#Cc1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1,,ClCCl,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20010027209A1,CCCc1cc(=O)oc2c3c(c4c(c12)OC(C)(C)C=C4)O[C@@H](C)[C@H](C)[C@H]3O>>CCCc1cc(=O)oc2c3c(c4c(c12)OC(C)(C)C=C4)O[C@@H](C)[C@H](C)[C@@H]3O,,ClCCl,,CO,,test
US04165378,CNC(=NC#N)NCCSCc1csc(NC(N)=NC(C)=O)n1>>CNC(=NC#N)NCCSCc1csc(NC(=N)N)n1,,CO,,[Na+].[OH-],,test
US20090143361A1,COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)cc(Cl)c4)n3c2n1.OB(O)c1ccsc1>>COc1ccc2nc(C)c3c(C)nc(-c4ccsc4)n3c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20060004078A1,CCOP(=O)(Cc1ccccc1)OCC.CN(C)CC(C)(C)C=O>>CN(C)CC(C)(C)C=Cc1ccccc1,,C1CCOC1,O,[Li]CCCC,,test
US20120270870A1,CC(C)(C)OC(=O)NC1(C(=N)N)CC1.CN(C)C=C(Br)C=O>>CC(C)(C)OC(=O)NC1(c2ncc(Br)cn2)CC1,,CO,,CCO,Cl,test
US05958952,CCOC(=O)CN1CCC(CCC(=O)O)CC1.Cl.O=S(Cl)Cl>>CCOC(=O)CN1CCC(CCC(=O)Cl)CC1.Cl,,ClCCl,,,,test
US20030125435A1,O=C(O)c1ccc(O)cc1.OCCCCCCCl>>O=C(O)c1ccc(OCCCCCCO)cc1,,[K+],[OH-],,,test
US20050003449A1,Cn1c(C(=O)[O-])cc2ccccc21>>Cn1c(CO)cc2ccccc21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110003801A1,FC(F)(F)c1ccc(CBr)cc1.O=S(=O)(Nc1nc2cccc3c2n1CCO3)c1ccccc1>>O=S(=O)(c1ccccc1)N(Cc1ccc(C(F)(F)F)cc1)c1nc2cccc3c2n1CCO3,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20060094767A1,CN(C(=O)OC(C)(C)C)C1CCN(CC2(C)CO2)CC1.O=[N+]([O-])c1c[nH]c(Cl)n1>>CN(C(=O)OC(C)(C)C)C1CCN(CC2(C)Cn3cc([N+](=O)[O-])nc3O2)CC1,,CCCO,,CC(=O)[O-].[Na+],,test
US20050043388A1,COC(=O)c1ccc(N)cc1.O=C(O)CCc1ccc2c(c1)OCO2>>COC(=O)c1ccc(NC(=O)CCc2ccc3c(c2)OCO3)cc1,,C1CCOC1,CCOCC,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20130261107A1,O=C(Cl)c1ccccc1F.O=C1CCNCC1>>O=C1CCN(C(=O)c2ccccc2F)CC1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US08003783B2,CCOC(=O)c1[nH]nc2c1CC1C3CCc4cc(OCc5ccccc5)ccc4C3CCC21C>>CCOC(=O)c1[nH]nc2c1CC1C3CCc4cc(O)ccc4C3CCC21C,[Pd],C1CCOC1,CCO,,,test
US20110124665A1,C=CC#N.COc1ccc(-c2c(-c3ccccc3)oc3ncnc(O[C@@H]4CCC[C@H](O)C4)c23)cc1>>COc1ccc(-c2c(-c3ccccc3)oc3ncnc(O[C@@H]4CCC[C@H](OCCC#N)C4)c23)cc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20120295885A1,COC(=O)c1ccc(-c2cccc(-n3ncc4cc(C(C)(C)C)ccc4c3=O)c2CO)n1C>>Cn1c(C(=O)O)ccc1-c1cccc(-n2ncc3cc(C(C)(C)C)ccc3c2=O)c1CO,,C1COCCO1,,O,[Na+].[OH-],test
US20020177578A1,Cc1cc(=O)cc(Cc2ccccc2)o1.NO>>CC1=CC(N)=CC(Cc2ccccc2)O1,,CO,,Cl,CC(=O)[O-].[Na+],test
US20050267095A1,CO.O=C(O)C1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1>>COC(=O)C1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1,,CCOC(C)=O,,O=S(Cl)Cl,,test
US20150353552A1,CCn1c(-c2cnc(C)nc2)nc2c(O[C@H]3CCCN(C(=O)OC(C)(C)C)C3)ncnc21>>CCn1c(-c2cnc(C)nc2)nc2c(O[C@H]3CCCNC3)ncnc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150329538A1,CC(C)(C)OC(=O)N1CCC[C@H](Nc2ccc3cccc(-c4cc5c([nH]4)CCNC5=O)c3n2)C1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C1NCCc2[nH]c(-c3cccc4ccc(N[C@H]5CCCNC5)nc34)cc21,,ClCCl,,,,test
US20100016399A1,COc1ccc(C2CC3(CCCCC3)N(CC(=O)O)C2=O)cc1.O=C(Cl)C(=O)Cl>>COc1ccc(C2CC3(CCCCC3)N(CC(=O)Cl)C2=O)cc1,CN(C)C=O,ClCCl,,,,test
US20030069297A1,Cc1cc(C)c(C=O)[nH]1.O=C1Cc2c(cccc2-c2cccc(F)c2)N1>>Cc1cc(C)c(C=C2C(=O)Nc3cccc(-c4cccc(F)c4)c32)[nH]1,C1CCNCC1,CCO,,,,test
US20150038528A1,Cc1ccccc1O.N#Cc1ccc([N+](=O)[O-])cc1C#N>>Cc1ccccc1Oc1ccc(C#N)c(C#N)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US08541418B2,CC[C@@H]1C(=O)N(C)c2cnc(Cl)nc2N1C1CCCC1.c1c[nH]c(C2CC2)n1>>CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3C3CC3)nc2N1C1CCCC1,[Pd],,,,,test
US20050209226A1,CC(C)(C)OC(=O)N1C2CCC1CC(=CCOCC1CC1)C2>>C(COCC1CC1)=C1CC2CCC(C1)N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060142575A1,CCOC(=O)c1nc(O)c2cc(O)ccc2n1.N>>NC(=O)c1nc(O)c2cc(O)ccc2n1,,CO,,,,test
US20150126490A1,CC(C)(C)[Si](C)(C)O[C@H]1CCC[C@@H](c2cnc(N)cn2)C1.O=C1CCC(=O)N1Br>>CC(C)(C)[Si](C)(C)OC1CCCC(c2cnc(N)c(Br)n2)C1,,CC#N,,,,test
US20140288040A1,CC[C@@H](NC(=O)OC(C)(C)C)c1ccc(Cl)c(Oc2ccnc(NC(C)=O)c2)c1F.Cl>>CC[C@@H](N)c1ccc(Cl)c(Oc2ccnc(NC(C)=O)c2)c1F.Cl,,CCOC(C)=O,,,,test
US20020193596A1,COC(=O)c1ccc([N+](=O)[O-])cc1-c1ccccc1>>COC(=O)c1ccc(N)cc1-c1ccccc1,[Pd],CO,,O=C[O-].[NH4+],,test
USRE039916E1,COC(=O)COc1ccc(S)c2c1CCC2.FC(F)(F)c1ccc(-c2ccc(CCl)cc2)cc1>>O=C(O)COc1ccc(SCc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)c2c1CCC2,,CC(=O)O,,,,test
US20070270466A1,CN1CCC(N(C)c2cc(N)cc(F)c2)CC1.O=C(Cl)c1ccc(F)cc1Cl>>CN1CCC(N(C)c2cc(F)cc(NC(=O)c3ccc(F)cc3Cl)c2)CC1,,C1COCCO1,,,,test
US20030199573A1,C=O.CC1(C)OC(=O)CC(=O)O1.CCO.O=c1cc(O)c2ccccc2o1>>CCOC(=O)CCc1c(O)c2ccccc2oc1=O,,CCO,,C,O=C[O-].[NH4+],test
US20110136780A1,Cc1ccc(S(=O)(=O)n2cc3c4c(ccnc42)CN([C@@H](C(=O)OC(C)(C)C)C(C)C)C3=O)cc1>>CC(C)[C@H](C(=O)O)N1Cc2ccnc3[nH]cc(c23)C1=O,,ClCCl,,CO,[Na+].[OH-],test
US06455737B1,Cc1ccc(N)c(O)c1.O=C(Cl)CCl>>Cc1ccc(NC(=O)CCl)c(O)c1,,C1CCOC1,,CCN(CC)CC,,test
US20060211734A1,CN1CCC(Sc2cc(N)cc(F)c2)CC1.O=C(Cl)c1ccc(F)cc1Cl>>CN1CCC(Sc2cc(F)cc(NC(=O)c3ccc(F)cc3Cl)c2)CC1,,C1COCCO1,,,,test
US04959361,C#CC1(C)CCc2c(C)c(O)c(C)c(C)c2O1.Cc1nnc2n1-c1ccc(I)cc1C(c1ccccc1F)=NC2>>Cc1c(C)c2c(c(C)c1O)CCC(C)(C#Cc1ccc3c(c1)C(c1ccccc1F)=NCc1nnc(C)n1-3)O2,,ClCCl,,CCO,,test
US07728014B2,CCOC(=O)c1ccc(-c2ccc(CC)cc2)c(-c2ccccc2)n1.CO>>CCc1ccc(-c2ccc(C(=O)OC)nc2-c2ccccc2)cc1,O=S(=O)(O)O,CO,,,,test
US05039676,BrC(Br)(Br)Br.CC(C)(C)C#CC#CCO>>CC(C)(C)C#CC#CCBr,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070149547A1,CNc1ncc(Cl)nc1C(=O)OC>>CNc1ncc(Cl)nc1C(=O)O,,ClCCl,,Cl,[Li+].[OH-],test
US20130102600A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1nc2sc(-c3ccccc3)cc2c(=O)[nH]1>>CC(C)(C)OC(=O)Nc1nc2sc(-c3ccccc3)cc2c(=O)[nH]1,CN(C)c1ccncc1,CN(C)C=O,,,,test
US20150299192A1,CCOC(CNC1=CC(=O)N(C(=O)OC(C)(C)C)CC1)OCC.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C1NCCc2[nH]ccc21,,ClCCl,,COC(C)(C)C,,test
US20090182002A1,CS(=O)(=O)Cl.OC[C@H]1COCCO1>>CS(=O)(=O)OC[C@H]1COCCO1,,ClCCl,,CCN(CC)CC,,test
US20100113511A1,CCCCc1ccc(CCCCBr)cc1.Cc1ccccn1>>CCCCc1ccc(CCCC[n+]2ccccc2C)cc1.[Br-],,CC#N,,,,test
US20110207777A1,CO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C)cc(F)c3[N+](=O)[O-])CC2)CC1>>CO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C)cc(F)c3N)CC2)CC1,[Ni],CCO,,NN,O,test
US20090181928A1,Nc1cc(F)cc(F)c1OCc1ccccc1.O=C1CCC(=O)N1Br>>Nc1cc(F)c(Br)c(F)c1OCc1ccccc1,,ClCCl,,,,test
US20090156642A1,Cc1ccc(S(=O)(=O)c2cc(CN(C)C(=O)OC(C)(C)C)nn2-c2cccc(F)c2C)cn1>>Cc1c(F)cccc1-n1nc(CN(C)C(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccnc1,,CCO,,CCN(CC)CC,,test
US05763489,CCOC(=O)CBr.C[C@H](NC1CCc2c(O)cccc2C1)c1ccccc1>>CCOC(=O)COc1cccc2c1CCC(N[C@@H](C)c1ccccc1)C2,,CS(C)=O,,[H-].[Na+],,test
US20120142717A1,CSc1nc(=O)c(Cc2cnc(C)nc2)c[nH]1.NCCc1ccc(Oc2ccc(C(F)(F)F)c(Cl)c2)cc1>>Cc1ncc(Cc2c[nH]c(NCCc3ccc(Oc4ccc(C(F)(F)F)c(Cl)c4)cc3)nc2=O)cn1,,CCO,,,,test
US20100210619A1,Nc1ccc(O)cc1.O=C(O)c1cc(NCC2CCCCC2)ncn1>>O=C(Nc1ccc(O)cc1)c1cc(NCC2CCCCC2)ncn1,,CCOC(C)=O,,,,test
US20140121377A1,Nc1ccc(I)cn1.O=C(CBr)c1ccc(-n2cccn2)nc1>>Ic1ccc2nc(-c3ccc(-n4cccn4)nc3)cn2c1,,CC#N,,,,test
US20040067998A1,Cc1c(C(C)O)c2ccccc2n1Cc1ccc(Cl)cc1Cl.O=C(n1ccnc1)n1ccnc1>>Cc1c(C(C)n2ccnc2)c2ccccc2n1Cc1ccc(Cl)cc1Cl,,C1CCOC1,,,,test
US20070106074A1,CCOC(=O)c1ccc(F)c([N+](=O)[O-])c1.COC(=O)c1ccccc1S>>CCOC(=O)c1ccc(Sc2ccccc2C(=O)OC)c([N+](=O)[O-])c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100063055A1,CC(C)I.CC1C(=O)C(C)(C)N(C(=O)OC(C)(C)C)c2c1cc(Br)c1c2CCC1>>CCCC1(C)C(=O)C(C)(C)N(C(=O)OC(C)(C)C)c2c1cc(Br)c1c2CCC1,,Cc1ccccc1,O,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US04242121,Cc1ccccc1Oc1ccc(Cl)cc1C(=O)Cl>>Cc1ccccc1Oc1ccc(Cl)cc1C=O,[Pd],Cc1ccccc1,,,,test
US20080269210A1,Cc1c(-c2cccc(S(C)(=O)=O)c2)sc2c(N3CCOCC3)nc(-c3ccc(N(C)C(=O)OC(C)(C)C)nc3)nc12>>CNc1ccc(-c2nc(N3CCOCC3)c3sc(-c4cccc(S(C)(=O)=O)c4)c(C)c3n2)cn1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110015157A1,C=CCC(O)(CCN[C@H]1CCCN(C(=O)OC(C)(C)C)C1)c1ccc(F)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>C=CCC1(c2ccc(F)cc2)CCN([C@H]2CCCN(C(=O)OC(C)(C)C)C2)C(=O)O1,,ClCCl,,CCN(CC)CC,O,test
US20120010228A1,CC(C)(C)OC(=O)c1ccc(N2CN(c3ccccc3)C3(CCN(C(=O)OCc4ccccc4)CC3)C2=O)cc1>>CC(C)(C)OC(=O)c1ccc(N2CN(c3ccccc3)C3(CCNCC3)C2=O)cc1,[Pd],CCOC(C)=O,CO,,,test
US20020193614A1,COc1ccc(CNC(=O)c2cc([N+](=O)[O-])ccc2N[C@@H]2CC[C@@H](NC(=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)CC2)cc1OC.Cl>>COc1ccc(CNC(=O)c2cc([N+](=O)[O-])ccc2N[C@@H]2CC[C@@H](NC(=N)N)CC2)cc1OC.Cl,,CCOC(C)=O,,,,test
US20120115844A1,COC(=O)c1ccc(C)nc1.Cn1nnc(-c2ccc(F)cc2)c1C=O>>COC(=O)c1ccc(/C=C/c2c(-c3ccc(F)cc3)nnn2C)nc1,,CC(=O)O,CC(=O)OC(C)=O,O,[Na+].[OH-],test
US04677111,Clc1cnc(Cl)nc1.Nc1ccc(O)c([N+](=O)[O-])c1>>Nc1ccc(-c2ncc(Cl)cn2)c([N+](=O)[O-])c1,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US05070089,C=O.COc1cc(C=O)ccc1O.CSC(=S)N1CCNCC1>>COc1cc(C=O)cc(CN2CCN(C(=S)SC)CC2)c1O,,CCO,,,,test
US20120083501A1,CN1C(=O)C2(N=C1N)c1cc(Br)ccc1OC1CC(=O)CCC12.OB(O)c1cc(F)cc(Cl)c1>>CN1C(=O)C2(N=C1N)c1cc(-c3cc(F)cc(Cl)c3)ccc1OC1CC(=O)CCC12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US04335127,O=C(NCCCN1CCC(C(=O)c2ccc(F)cc2)CC1)c1ccccc1[N+](=O)[O-]>>Nc1ccccc1C(=O)NCCCN1CCC(C(=O)c2ccc(F)cc2)CC1,[Pt],CO,,CCO,[H][H],test
US04370340,CCOC(=O)Cn1c(=O)oc2cc(-c3ccccc3)c(Cl)cc21>>O=C(O)Cn1c(=O)oc2cc(-c3ccccc3)c(Cl)cc21,,CC(=O)O,O,Cl,,test
US20110171159A1,O=C(Cl)c1cc(I)ccc1Br.c1ccc2c(c1)OCCO2>>O=C(c1ccc2c(c1)OCCO2)c1cc(I)ccc1Br,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20160244429A1,COc1ccc2[nH]cc(CCCCOS(=O)(=O)c3ccc(C)cc3)c2c1.Cc1ccn(-c2ccc(N3CCNCC3)cc2)c(=O)c1>>COc1ccc2[nH]cc(CCCCN3CCN(c4ccc(-n5ccc(C)cc5=O)cc4)CC3)c2c1,,CC#N,,[I-].[K+],,test
US04920128,COc1ccc2cc(C#N)c(Cl)nc2c1.NNc1ccccc1>>COc1ccc2cc3c(N)nn(-c4ccccc4)c3nc2c1,,CN(C)C=O,,[H-].[Na+],,test
US20140094462A1,C#CCCC(=O)N[C@@H](COC(=O)C(C)(C)CC=C)c1ccccc1.CCO[SiH](OCC)OCC>>C=CCC(C)(C)C(=O)OC[C@H](NC(=O)CCC(=C)[Si](OCC)(OCC)OCC)c1ccccc1,,ClCCl,,,,test
US20120015975A1,CCC(C)N.O=[N+]([O-])c1cc(C(F)(F)F)ccc1F>>CCC(C)Nc1ccc(C(F)(F)F)cc1[N+](=O)[O-],,O,,CN1CCCC1=O,,test
US20100160362A1,C=O.O=C1C(c2nc3c(cc2O)OCO3)c2ccccc2N1Cc1ccc(C(F)(F)F)o1>>O=C1N(Cc2ccc(C(F)(F)F)o2)c2ccccc2C1(CO)c1nc2c(cc1O)OCO2,,C1CCOC1,,,,test
US05463064,O=C(O)[C@H](O)c1ccccc1.OC1CCN(Cc2ccccc2)C1>>O=C([O-])C(O)c1ccccc1.O[C@H]1CCN(Cc2ccccc2)C1,,CC(C)=O,,,,test
US20100267722A1,N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3Cl)CN2)CC1.O=COc1ccc([N+](=O)[O-])cc1>>N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3Cl)CN2C=O)CC1,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US06110924,Br.Cc1ccc(C2C(=O)NC(=O)NC2=O)cc1>>Cc1ccc(C2(Br)C(=O)NC(=O)NC2=O)cc1,,O,,,,test
US20150266850A1,CC(=O)NCc1cc(C(C)=O)ccc1C>>CC(=O)c1ccc(C)c(CN)c1,,O,,O=S(=O)(O)O,,test
US20050154158A1,C1=C2SCC=C2c2ccsc21.C1CCOC1.C=CCOc1c(C(C)(C)C)cc(C)cc1[Si](C)(C)Cl.[Li]CCCC>>C=CCOc1c(C(C)(C)C)cc(C)cc1[Si](CC)(CC)C1=C2SCC=C2c2ccsc21,,Cc1ccccc1,,,,test
US04386073,C1CCNCC1.CC(C)C[C@H](NC(=O)[C@@H]1CCC(=O)N1C(=O)OCc1ccccc1)C(=O)O>>C1CCNCC1.CC(C)C[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)O,[Pd],CO,,[H][H],,test
US20150197509A1,CN[C@@H](C)C(=O)NCc1cccc(-c2ccc(C(F)(F)F)cc2)c1.O=S(=O)(Cl)c1ccc(F)cc1>>C[C@@H](C(=O)NCc1cccc(-c2ccc(C(F)(F)F)cc2)c1)N(C)S(=O)(=O)c1ccc(F)cc1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20090062333A1,N#Cc1cccc(Br)c1F.OCc1ccccc1>>N#Cc1cccc(Br)c1OCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US05491167,C[C@H]1C=CC2=C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](OC(=O)C(C)(C)Oc3ccccc3)[C@@H]2[C@H]1CC[C@@H]1C[C@@H](O[Si](C)(C)C(C)(C)C)CC(=O)O1>>C[C@H]1C=CC2=C[C@@H](O)C[C@H](OC(=O)C(C)(C)Oc3ccccc3)[C@@H]2[C@H]1CC[C@@H]1C[C@@H](O)CC(=O)O1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20060270706A1,CC(C)(C)OC(=O)N1CCC(=O)C1.CCOC(=O)Cn1cc(C=O)cn1>>CCOC(=O)Cn1cc(/C=C2\CN(C(=O)OC(C)(C)C)CC2=O)cn1,,CCO,,C1CCNC1,,test
US20090099157A1,C=O.OC(CN1CCC(c2ccccn2)CC1)Cn1nc(-c2ccc(C(F)(F)F)c(SCCN3CCCCC3)c2)c2c1CCNC2>>CN1CCc2c(c(-c3ccc(C(F)(F)F)c(SCCN4CCCCC4)c3)nn2CC(O)CN2CCC(c3ccccn3)CC2)C1,,CC#N,,[BH3-]C#N.[Na+],,test
US20020049317A1,CS(=O)(=O)c1ccc(C(=O)O)c([N+](=O)[O-])c1.O=[N+]([O-])c1ccc(O)cc1>>CS(=O)(=O)c1ccc(C(=O)Oc2ccc([N+](=O)[O-])cc2)c([N+](=O)[O-])c1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20120136008A1,CC(C)c1ccc2c3c([nH]c2c1)CCN(C)C3.CC1(c2ccncc2)CO1>>CC(C)c1ccc2c3c(n(CC(C)(O)c4ccncc4)c2c1)CCN(C)C3,,CN(C)C=O,,[H-].[Na+],,test
US20050222230A1,NN.O=c1c(-c2cccc(Br)c2)coc2cc(O)c(Cl)cc12>>Oc1cc(O)c(-c2n[nH]cc2-c2cccc(Br)c2)cc1Cl,,CCO,,O,,test
US20040116694A1,COc1ccc(F)cc1C1(CC(O)(CNc2cccc3nc(C)ccc23)C(F)(F)F)CC1>>Cc1ccc2c(NCC(O)(CC3(c4cc(F)ccc4O)CC3)C(F)(F)F)cccc2n1,,ClCCl,,BrB(Br)Br,,test
US20120245170A1,CCOC(=O)C(=O)CBr.N#Cc1cc2c(NC(=N)S)n[nH]c2nc1-c1ccc(O)cc1F>>CCOC(=O)c1csc(Nc2n[nH]c3nc(-c4ccc(O)cc4F)c(C#N)cc23)n1,,CCO,,,,test
US20100298336A1,CCn1cnc(C=O)c1C>>CCn1cnc(CO)c1C,,CO,,O,[BH4-].[Na+],test
US20160264582A1,CS(=O)(=O)Cl.O=C1[C@@H]2CNC[C@@H]2CN1c1cccc2c1cnn2-c1ccccc1F>>CS(=O)(=O)N1C[C@@H]2CN(c3cccc4c3cnn4-c3ccccc3F)C(=O)[C@@H]2C1,,ClCCl,,CCN(CC)CC,,test
US20150284375A1,CC(C)(C)OC(=O)NCc1nc(CCl)cs1.Oc1ccc(C(F)(F)F)cc1>>Cl.NCc1nc(COc2ccc(C(F)(F)F)cc2)cs1,,CCOC(C)=O,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US05162326,CCCCn1c(=O)cc(Cl)n(Cc2ccc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)c1=O.CCCS>>CCCCn1c(=O)cc(SCCC)n(Cc2ccc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)c1=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080132503A1,CCOC(=O)c1ccc(NC(N)=S)cc1.O=C(CBr)c1cccnc1>>CCOC(=O)c1ccc(Nc2nc(-c3cccnc3)cs2)cc1,,O,,,,test
US20050085639A1,CCS([NH-])(=O)=O.COc1ccccc1Oc1c(Cl)nc(-c2ncccn2)nc1Cl>>CCS(=O)(=O)Nc1nc(-c2ncccn2)nc(Cl)c1Oc1ccccc1OC,,CS(C)=O,,Cl,,test
US20100184973A1,O=C(NOCCO)c1cccnc1SCc1ccccc1>>c1ccc(CSc2ncccc2C2=NOCCO2)cc1,,C1CCOC1,,O=S(Cl)Cl,,test
US20030065174A1,CCCC[Mg]Cl.CN(CCC=O)C(=O)OC(C)(C)C>>CCCCC(O)CCN(C)C(=O)OC(C)(C)C,,C1CCOC1,,[Cl-].[NH4+],,test
US20090099231A1,CC(C)(C)OC(=O)N1CCc2cc([N+](=O)[O-])c(F)cc2C1>>CC(C)(C)OC(=O)N1CCc2cc(N)c(F)cc2C1,[Pd],CCO,,,,test
US20110021515A1,OCc1c(N2CC3CCC(C2)O3)nc(Cl)nc1C1(O)CC1>>Clc1nc(N2CC3CCC(C2)O3)c2c(n1)C1(CC1)OC2,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04623659,NC(=O)c1cc(O)c(O)c(O)c1>>N#Cc1cc(O)c(O)c(O)c1,,CCOC(C)=O,,O=S(Cl)Cl,,test
US20090240052A1,Cc1cccc(C(=O)Nc2cc(-c3cc4ccccc4o3)ccc2C(=O)OC(C)(C)C)c1C>>Cc1cccc(C(=O)Nc2cc(-c3cc4ccccc4o3)ccc2C(=O)O)c1C,,O=C(O)C(F)(F)F,,,,test
US20130210632A1,ClCCBr.c1coc(CNc2ncnc3nc[nH]c23)c1>>ClCCn1cnc2c(NCc3ccco3)ncnc21,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US03932416,Nc1nnn[nH]1.O=COCCOc1cc(C(=O)O)nc2ccccc12>>O=COCCOc1cc(C(=O)Nc2nnn[nH]2)nc2ccccc12,,C1CCOC1,CN(C)C=O,,,test
US06177423B1,COS(=O)(=O)OC.O=C1c2cccc3c(Br)c(O)cc(c23)C(=O)N1OCc1ccccc1>>COc1cc2c3c(cccc3c1Br)C(=O)N(OCc1ccccc1)C2=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080262214A1,CC(=O)O[C@@]1(O)[C@@](O)(OC(C)=O)[C@@H](CO)O[C@@]1(OC(C)=O)N1CN=C2C1=NC=NC2(N)Cl>>NC1(Cl)N=CN=C2C1=NCN2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O,,ClCCl,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US20080021217A1,CN1CCOCC1.NCc1nc(-c2ccncc2)nn1CCBr>>c1cc(-c2nc3n(n2)CCNC3)ccn1,,CO,,Br,,test
US20030088079A1,CC(C)(C)[Si](OC[C@H]1O[C@@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)[C@H](OCC(O)CO)[C@@H]1O)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](OC[C@H]1O[C@@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)[C@H](OCC=O)[C@@H]1O)(c1ccccc1)c1ccccc1,,ClCCl,,CO,,test
US20060199817A1,CN.Cc1ccc(C(=O)O)cc1-c1ccc2c(NC(C)C)nncc2c1>>CNC(=O)c1ccc(C)c(-c2ccc3c(NC(C)C)nncc3c2)c1,,CN(C)C=O,ClCCl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20110076292A1,COC(OC)N(C)C.NC(=O)c1cn2c(n1)-c1cnc(Cl)cc1OCC2>>CN(C)C=NC(=O)c1cn2c(n1)-c1cnc(Cl)cc1OCC2,,Cc1ccccc1,,,,test
US20100152165A1,CCOC(=O)CCc1ccc(COc2cccc3c2NCCC3)cc1F.COc1ccc(CBr)cc1>>CCOC(=O)CCc1ccc(COc2cccc3c2N(Cc2ccc(OC)cc2)CCC3)cc1F,,O,,CCN(C(C)C)C(C)C,CN(C)C=O,test
US20110059954A1,Cc1cc(C(=O)c2cc(Cl)ncn2)cc(C)c1OCc1ccccc1.O=c1[nH]c2ncccc2n1C1CCNCC1>>Cc1cc(C(=O)c2cc(N3CCC(n4c(=O)[nH]c5ncccc54)CC3)ncn2)cc(C)c1OCc1ccccc1,,CN(C)C=O,,,,test
US20070249587A1,NC(=O)c1sccc1N.O=C(O)c1cc(F)c(Br)cc1F>>NC(=O)c1sccc1NC(=O)c1cc(F)c(Br)cc1F,,C1CCOC1,,CCN(C(C)C)C(C)C,O=S(Cl)Cl,test
US20080085890A1,CN(C)CCSc1ccc(N)cc1.CO/C=C1/C(=O)NC(=O)c2ccc(Br)cc21>>CN(C)CCSc1ccc(N/C=C2\C(=O)NC(=O)c3ccc(Br)cc32)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20140357661A1,C[C@@H](CO)CF.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>C[C@H](CF)COS(=O)(=O)C(F)(F)F,,ClCCl,,Cc1cccc(C)n1,,test
US20110288067A1,C[C@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3ccc(C(=O)O)s3)nc12)C(C)(C)C.Nc1ccc(I)cc1Cl>>C[C@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3ccc(C(=O)Nc4ccc(I)cc4Cl)s3)nc12)C(C)(C)C,,c1ccncc1,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US04162154,CC1(C)COc2ccc(O)cc21.CCS(=O)(=O)Cl>>CCS(=O)(=O)Oc1ccc2c(c1)C(C)(C)CO2,,CCN(CC)CC,,,,test
US20150366776A1,CCCC(C)(Oc1ccc(C=O)cc1)C(=O)O.Nc1ccccc1S>>CC(C)(C)Oc1ccc(-c2nc3ccccc3s2)cc1,,CO,,,,test
US05061705,CC1(C)CCC(C)(C)c2cc(C(=O)Cl)ccc21.Cc1ccc(C(N)=NO)cc1>>Cc1ccc(-c2noc(-c3ccc4c(c3)C(C)(C)CCC4(C)C)n2)cc1,,C1COCCO1,,FB(F)F,,test
US20040248903A1,CSc1nccc(C#C[Si](C)(C)C)n1>>C#Cc1ccnc(SC)n1,,CO,,[F-].[K+],,test
US20060280746A1,COc1cc(OC)c(/C=C/C(c2ccc(OC)c([N+](=O)[O-])c2)S(=O)C(/C=C/c2c(OC)cc(OC)cc2OC)c2ccc(OC)c([N+](=O)[O-])c2)c(OC)c1>>COc1cc(OC)c(/C=C/C(c2ccc(OC)c(N)c2)S(=O)C(/C=C/c2c(OC)cc(OC)cc2OC)c2ccc(OC)c(N)c2)c(OC)c1,,CC(C)=O,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20020107269A1,CNc1ccc(C)cc1[N+](=O)[O-]>>CNc1ccc(C)cc1N,[Fe],CCO,O,Cl,,test
US04211726,Cc1ccc2c(CO)c3ccccc3c(C=O)c2c1>>Cc1ccc2c(C=O)c3ccccc3c(C=O)c2c1,,O,,CCN(CC)CC,CS(C)=O,test
US20090111776A1,CCCN1CCCC1C(=O)OCc1ccccc1>>CCCN1CCC[C@H]1C(=O)O,[Pd],CO,,,,test
US20110319424A1,CC1(N)CCN(C(=O)OC(C)(C)C)CC1.O=Cc1ccc(C(F)(F)F)nc1>>CC1(NCc2ccc(C(F)(F)F)nc2)CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20120295915A1,Nc1cccnc1NC[C@@H]1CCN(C(=O)C2CC2)C1.O=Cc1ccc(-c2cccc(C(=O)O)c2)cc1>>O=C(O)c1cccc(-c2ccc(-c3nc4cccnc4n3C[C@@H]3CCN(C(=O)C4CC4)C3)cc2)c1,,CN1CCCC1=O,,,,test
US20130102576A1,COC(=O)CBr.O=C1Nc2ccc([N+](=O)[O-])cc2C1=O>>COC(=O)CN1C(=O)C(=O)c2cc([N+](=O)[O-])ccc21,,CCOC(C)=O,CN(C)C=O,Cl,[H-].[Na+],test
US20080085886A1,CB1OB(C)OB(C)O1.CCOC(=O)c1oc2ccnc(Cl)c2c1Nc1ccc([Si](C)(C)C)cc1F>>CCOC(=O)c1oc2nccc(C)c2c1Nc1ccc([Si](C)(C)C)cc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20090124596A1,CC(C)(C)OC(=O)N1CCN(Cc2ccc(-c3cccc(-n4c(=O)n([C@@H]5CC[C@H](NC(=O)c6cn7cc(F)ccc7n6)CC5)c(=O)c5cc(F)cnc54)c3)cc2)CC1>>O=C(N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccc(CN5CCNCC5)cc4)c3)c2=O)CC1)c1cn2cc(F)ccc2n1,,C1COCCO1,,Cl,,test
US20160000760A1,CC(C)(COc1ccc(Br)cc1)NC(=O)OC(C)(C)C.CI>>CN(C(=O)OC(C)(C)C)C(C)(C)COc1ccc(Br)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20110112135A1,CC(C)(C)C(=O)CBr.N#Cc1cccnc1N>>CC(C)(C)c1cn2cccc(C#N)c2n1,,CCO,,,,test
US20050191238A1,CCCC(=O)Cl.OCCCCc1ccccc1>>CCCC(=O)OCCCCc1ccccc1,,ClCCl,,,,test
US20150361031A1,CC(C)(C)OC(=O)NCCOc1ccc(Cl)cc1C(=O)Nc1ccc([N+](=O)[O-])cc1Cl>>NCCOc1ccc(Cl)cc1C(=O)Nc1ccc([N+](=O)[O-])cc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110269712A1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.COC(=O)c1cc[nH]n1>>COC(=O)c1ccn(C2CCN(C(=O)OC(C)(C)C)CC2)n1,,CN(C)C=O,,[H-].[Na+],,test
US05082967,CCOC(=O)CCCCCCCI.CCOCCCCCS>>CCOCCSCCCCCCCC(=O)OCC,,CCCCCC,,C1CCOC1,[H-].[Na+],test
US20150361100A1,OCc1cc2ccc(C(F)(F)F)cn2c1-c1ccccn1>>O=Cc1cc2ccc(C(F)(F)F)cn2c1-c1ccccn1,O=[Mn]=O,,,,,test
US20120252805A1,Cc1cc(NS(=O)(=O)c2cccc(Cl)c2)c2c(Br)c(C)sc2n1.Cc1ccc(B2OC(C)(C)C(C)(C)O2)o1>>Cc1cc(NS(=O)(=O)c2cccc(Cl)c2)c2c(-c3ccc(C)o3)c(C)sc2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120115846A1,CC(O)F.COc1ccc(Cn2c(=O)c3cc(O)ccc3n(C3CCOCC3)c2=O)cc1OC>>COc1ccc(Cn2c(=O)c3cc(OCCF)ccc3n(C3CCOCC3)c2=O)cc1OC,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060183736A1,BrCc1ccccc1.COc1ccc2c(Br)c(O)ccc2c1>>COc1ccc2c(Br)c(OCc3ccccc3)ccc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06235731B1,BrCc1ccccc1.CC#N.C[C@@H]1CN(C(=O)OC(C)(C)C)[C@@H](C)CN1>>CCCCOC(=O)N1C[C@@H](C)N(Cc2ccccc2)C[C@@H]1C,,CC#N,,CCN(CC)CC,,test
US06495581B1,Cc1oc(-c2ccccc2)nc1CCl.OCCCc1ccc(O)cc1>>Cc1oc(-c2ccccc2)nc1COc1ccc(CCCO)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080146566A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20150344468A1,CCOC(=O)COc1ccc(Br)nc1.COCn1c(=O)sc2cc(C(C)c3cc[nH]n3)ccc21>>CCOC(=O)COc1ccc(-n2ccc(C(C)c3ccc4c(c3)sc(=O)n4COC)n2)nc1,[Cu]I,CS(C)=O,,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US20140275083A1,C[C@H](N[S@](=O)C(C)(C)C)c1cc(-c2ccc(Cl)cc2)on1>>C[C@H](N)c1cc(-c2ccc(Cl)cc2)on1,,C1COCCO1,,Cl,,test
US05464848,C#CCCCO.CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1>>C#CCCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,CN(C)C=O,O,c1c[nH]cn1,,test
US04696938,Cc1cccc(-c2ccccc2Cl)n1.O=[Se]=O>>O=Cc1cccc(-c2ccccc2Cl)n1,,C1COCCO1,,,,test
US20080125468A1,CCCCCCC(Oc1ccc(C(=O)NCCC(=O)OCC)cc1F)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1>>CCCCCCC(Oc1ccc(C(=O)NCCC(=O)O)cc1F)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1,,CCO,,[Na+].[OH-],,test
US20110257151A1,CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(N)c1)N2.CN1CCN(C(=O)Cl)CC1>>CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(NC(=O)N3CCN(C)CC3)c1)N2,,ClCCl,,Cl,c1ccncc1,test
US20040235822A1,O=[N+]([O-])c1ccc(CSc2ccccn2)cc1>>Nc1ccc(CSc2ccccn2)cc1,,CC(=O)O,,,,test
US20080114002A1,N#Cc1cccc(O)c1.O=Cc1ccc(C(F)(F)F)cc1F>>N#Cc1cccc(Oc2cc(C(F)(F)F)ccc2C=O)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05767282,CC(C)(C)[Si](C)(C)Cl.COC(=O)CO>>COC(=O)CO[Si](C)(C)C(C)(C)C,,CN(C)C=O,,O,c1c[nH]cn1,test
US20050101587A9,CC(C)(C)OC(=O)N1CCC(Nc2ncccc2O)CC1.CCOC(=O)CBr>>CCOC(=O)COc1cccnc1NC1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,[H-].[Na+],,test
US20100069457A1,CCOC(=O)Cc1ccc(N2Cc3c(c(OCC)c4ccccc4c3OCC(F)F)C2=O)c(F)c1>>CCOc1c2c(c(OCC(F)F)c3ccccc13)CN(c1ccc(CC(=O)O)cc1F)C2=O,,CCO,,[Na+].[OH-],,test
US05593993,CCN=C=S.Nc1nccs1>>CCNC(=S)Nc1nccs1,,CN(C)C=O,,CCOC(C)=O,,test
US20160168156A1,CC(C)(C)OC(=O)NCCCC(=O)c1cc(F)ccc1F>>Fc1ccc(F)c(C2=NCCC2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US03989698,CC(=O)OC(C)=O.NO.O=c1[nH]c2ccccc2c(=O)o1>>Cc1nc2ccccc2c(O)[n+]1[O-],,c1ccncc1,,Cl,,test
US20120040981A1,CC(=O)N1CCC(=O)CC1.NC(=O)c1sc(-c2ccncc2)cc1N>>CC(=O)N1CCC2(CC1)NC(=O)c1sc(-c3ccncc3)cc1N2,,CC(=O)O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05466861,CCOC(=O)/C=C(\C)C(O)CC(=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C>>CCOC(=O)/C=C/C=C/C(=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C,,C1CCOC1,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20020156087A1,CN1CCNCC1.O=C(CCl)c1ccc(Cl)cc1Cl>>CN1CCN(CC(=O)c2ccc(Cl)cc2Cl)CC1,,CN(C)C=O,,,,test
US20100016311A1,Cc1ccncc1.O=Cc1ccc(C(=O)O)cc1>>O=C(O)c1ccc(/C=C/c2ccncc2)cc1,,CC(=O)OC(C)=O,,,,test
US04478837,Cc1ccccc1C(=O)N1CCc2nnc(Cl)cc2C1.NN>>Cc1ccccc1C(=O)N1CCc2nnc(NN)cc2C1,,CCO,,O,,test
US20120058997A1,Clc1cccc(-c2cnc3ccc(Cl)nn23)c1.N[C@H]1CC[C@H](O)CC1>>OC1CCC(Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1,,CN1CCCC1=O,,Cl,O=C([O-])O.[Na+],test
US04439448,CCOC(=O)C(CC)c1ccc([N+](=O)[O-])cc1>>CCOC(=O)C(CC)c1ccc(N)cc1,[Pd],CCO,,,,test
US20110021506A1,O=C(O)[C@@H]1CC[C@@H](Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)CC1>>O=[N+]([O-])c1ccc(N[C@@H]2CC[C@@H](CO)CC2)cc1C(F)(F)F,,C1CCOC1,CCOC(C)=O,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20060041146A1,CCC(=O)c1csc(NC(=O)OC(C)(C)C)n1>>CCC(=O)c1csc(N)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100331335A1,O=C(O)Cc1cc([N+](=O)[O-])ccc1F>>Nc1ccc(F)c(CC(=O)O)c1,,C1CCOC1,CCO,O,[Cl-].[NH4+],test
US20020173506A1,CCOC(=O)CC(C)c1ccc(N)cn1.Cc1ccccc1Nc1nc2ccc(CC(=O)Nc3ccc(C(C)CC(=O)O)nc3)cc2[nH]1.O=C(O)C(F)(F)F>>CCOC(=O)CC(C)c1ccc(NC(=O)Cc2ccc3nc(Nc4ccccc4C)oc3c2)cn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04997954,CCCNCCC.O=C1Cc2c(CCBr)cccc2N1>>CCCN(CCC)CCc1cccc2c1CC(=O)N2,,Cl,,,,test
US08026235B1,COCCOCOc1c(Nc2ccc(OC)cn2)cccc1C(=O)OC>>COC(=O)c1cccc(Nc2ccc(OC)cn2)c1O,,CO,,,,test
US04657579,C#CCN(C(=O)CO)c1c(C)nc(N(C)C)nc1C.CS(=O)(=O)Cl>>C#CCN(C(=O)CCl)c1c(C)nc(N(C)C)nc1C,CN(C)c1ccncc1,ClCCl,O,,,test
US20110212945A1,Cc1cc([N+](=O)[O-])cnc1-c1ccccc1>>Cc1cc(N)cnc1-c1ccccc1,[Pd],CCO,,,,test
US20130178443A1,CC(C)C(=O)Cl.Nc1nc(C(=O)N2Cc3ccccc3C2)c2cc(-c3cc(F)c(F)cc3CO)ccc2n1>>CC(C)C(=O)OCc1cc(F)c(F)cc1-c1ccc2nc(N)nc(C(=O)N3Cc4ccccc4C3)c2c1,CN(C)c1ccncc1,CN(C)C=O,,CCOC(C)=O,O,test
US20100056502A1,CC(C)(C)OC(=O)N(Cc1cc2c(nn1)OCCO2)C1CCNCC1.O=CC1CCN2C(=O)COc3ccc(F)c1c32>>CC(C)(C)OC(=O)N(Cc1cc2c(nn1)OCCO2)C1CCN(CC2CCN3C(=O)COc4ccc(F)c2c43)CC1,CC(=O)O,ClC(Cl)Cl,,CO,,test
US20090239929A1,CC(C)(C)OC(=O)N1CC[C@H](N)C1.O=C(O)C(F)F>>CC(C)(C)OC(=O)N1CC[C@H](NC(=O)C(F)F)C1,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US05869516,CCOC(=O)CC(C)=O.NNc1ccc([N+](=O)[O-])cc1>>CC1=NN(c2ccc([N+](=O)[O-])cc2)C(=O)C1,,CCO,,Cl,,test
US20060058305A1,BrCc1ccccc1.Cc1cc(O)c2cc(-c3cccc(C(F)(F)F)c3)nnc2c1>>Cc1cc(OCc2ccccc2)c2cc(-c3cccc(C(F)(F)F)c3)nnc2c1,,CCCCCC,CCOC(C)=O,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20100130495A1,Cc1nccn1-c1ccc(Nc2nc3c(c(OS(=O)(=O)C(F)(F)F)n2)CN(C)CC3)cc1.NC1CC2CCC1C2>>Cc1nccn1-c1ccc(Nc2nc3c(c(N[C@@H]4CC5CCC4C5)n2)CN(C)CC3)cc1,,ClCCl,,,,test
US20090069340A1,CC(C)(C)OC(=O)N1CCC(CC=Cc2ccncc2)CC1>>CC(C)(C)OC(=O)N1CCC(CCCc2ccncc2)CC1,[Pt],CO,,[H][H],,test
US05659038,CCCC[Sn](C#C[Si](C)(C)C)(CCCC)CCCC.CCOC(=O)c1cn(C2CC2)c2c(F)c(N3CCN(C)CC3)c(F)c(Br)c2c1=O>>CCOC(=O)c1cn(C2CC2)c2c(F)c(N3CCN(C)CC3)c(F)c([Si](C)(C)C)c2c1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20100029617A1,CCCCOC(=O)CCc1cc(F)c(C(F)(F)F)c(F)c1>>O=C(O)CCc1cc(F)c(C(F)(F)F)c(F)c1,,CO,O,[Na+].[OH-],,test
US20040019113A1,Cn1nc(C(C)(C)C)cc1C(=O)Cl.Nc1ccc(C(F)(F)F)cc1>>Cn1nc(C(C)(C)C)cc1C(=O)Nc1ccc(C(F)(F)F)cc1,,ClCCl,,CCN(CC)CC,,test
US20090197877A1,CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(C(=O)OC)c2s1.NN>>CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(C(=O)NN)c2s1,,CO,O,,,test
US20110218182A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H]1CN(C(=O)OCc2ccccc2)C[C@H]1O>>CC(C)(C)OC(=O)NC1CN(C(=O)OCc2ccccc2)CC1O,,ClCCl,,CCN(CC)CC,,test
US20090233903A1,CCS(=O)(=O)N1CC(=CC#N)C1.C[Si](C)(C)CCOCn1ccc2c(-c3cn[nH]c3)ncnc21>>CCS(=O)(=O)N1CC(CC#N)(n2cc(-c3ncnc4c3ccn4COCC[Si](C)(C)C)cn2)C1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20100298324A1,COC(=O)c1ccc(C(=O)NCc2ccc(Cl)cc2)cc1N=C=S.Cc1csc(CN)n1>>Cc1csc(Cn2c(=S)[nH]c3cc(C(=O)NCc4ccc(Cl)cc4)ccc3c2=O)n1,,CS(C)=O,,Cl,,test
US20090197866A1,CN1CCCN(c2cc(N)c([N+](=O)[O-])cc2F)CC1>>CN1CCCN(c2cc(N)c(N)cc2F)CC1,[Pd],CO,,[H][H],,test
US20120115811A1,COc1ncc(-c2ccncc2)cc1NC(=O)[C@H](Cc1ccccc1)NC1(c2ccccn2)CC1>>O=C(Nc1cc(-c2ccncc2)c[nH]c1=O)[C@H](Cc1ccccc1)NC1(c2ccccn2)CC1,,C1COCCO1,,Cl,,test
US05095013,C=CCOC(=O)N1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)C[C@H]1/C=C\C(N)=O>>C=CCOC(=O)N1C[C@@H](S)C[C@H]1/C=C\C(N)=O,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20070104644A1,NC1(C(=O)OCc2ccccc2)CCCC1.O=S(=O)(Cl)c1ccc(-c2ccc(F)cc2)cc1>>O=C(OCc1ccccc1)C1(NS(=O)(=O)c2ccc(-c3ccc(F)cc3)cc2)CCCC1,,C1COCCO1,O,CCN(CC)CC,Cc1ccc(S(=O)(=O)O)cc1,test
US20100222324A1,NO.O=C1CCC(c2ccccc2)(N2CCC2)CC1>>ON=C1CCC(c2ccccc2)(N2CCC2)CC1,,CO,O,Cl,O=C([O-])O.[Na+],test
US20040209948A1,CCOC(=O)N1CCC(NS(=O)(=O)c2ccc(CN)c3ccccc23)CC1.Cc1ccccc1C(=O)Cl>>CCOC(=O)N1CCC(NS(=O)(=O)c2ccc(CNC(=O)c3ccccc3C)c3ccccc23)CC1,CN(C)c1ccncc1,ClCCCl,,c1ccncc1,,test
US20120245124A1,CC(C)[C@@H](N)CO.O=Cc1nc(Br)ccc1F>>CC(C)[C@H](CO)NCc1nc(Br)ccc1F,,CO,,[BH4-].[Na+],,test
US20050197338A1,CCc1cc(Br)ccc1-n1cc(NC(N)=O)c(C(N)=O)n1>>CCc1ccccc1-n1cc(NC(N)=O)c(C(N)=O)n1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20130079338A1,COc1nc(Nc2ccc(OC(F)F)cc2)ncc1CO.O=S(Cl)Cl>>COc1nc(Nc2ccc(OC(F)F)cc2)ncc1CCl.Cl,,ClCCl,,,,test
US20100010053A1,CC(C)(C)OC(=O)CCc1c[nH]c2cc(C(=N)NO)ccc12.CC(C)Oc1ccc(C(=O)O)cc1Cl>>CC(C)Oc1ccc(-c2nc(-c3ccc4c(CCC(=O)OC(C)(C)C)c[nH]c4c3)no2)cc1Cl,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20100331320A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.O=c1cc(O)ccn1C1CC1>>O=c1cc(OS(=O)(=O)C(F)(F)F)ccn1C1CC1,,ClCCl,,CCN(CC)CC,,test
US20110034464A1,COCCNS(=O)(=O)c1ccc(F)cc1CN.N#CC(C(N)=O)C1OC(=O)C(Cl)=C1Cl>>COCCNS(=O)(=O)c1ccc(F)cc1Cn1cc(Cl)cc(C(N)=O)c1=N.Cl,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US04005118,CCCCCCCCNC.CO[Si](CCCCl)(OC)OC>>CCCCCCCCC(CC[Si](OC)(OC)OC)NC,,CO,,C[O-].[Na+],,test
US20020198197A1,CC(C)(C)OC(=O)Nc1ccc(-n2cccc2)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1ccc(-n2cccc2)cc1N,[Pd],,,,,test
US20120225854A1,CC(C)(C)OC(=O)NCC(=O)O.CCOC(=O)[C@@H](N)Cc1cccnc1OC>>CCOC(=O)[C@H](Cc1cccnc1OC)NC(=O)CNC(=O)OC(C)(C)C,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150094306A1,CC(=O)Nc1nccc2c1CN(C(C)c1cnc(OCC(F)(F)F)c(C)c1)C2=O>>Cc1cc(C(C)N2Cc3c(ccnc3N)C2=O)cnc1OCC(F)(F)F,,C1CCOC1,,Cl,,test
US20110086841A1,C[C@H]1COCCN1c1nc(Cl)nc2c1ncn2C.O=C1CCOCC1>>C[C@H]1COCCN1c1nc(Cl)nc2c1nc(C1(O)CCOCC1)n2C,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20150266900A1,NNc1c(F)c(F)c(S(N)(=O)=O)c(F)c1F.O=Cc1ccccc1>>NS(=O)(=O)c1c(F)c(F)c(NN=Cc2ccccc2)c(F)c1F,,CO,,,,test
US20110039843A1,CCc1cnccc1C(=O)Cl.Nc1cc(C(F)(F)F)c(Cl)cc1O>>CCc1cnccc1C(=O)Nc1cc(C(F)(F)F)c(Cl)cc1O,,O,,CCN(CC)CC,CN(C)C=O,test
US04962115,CCOc1cc(NC(C)=O)ccc1C(=O)OC.O=[N+]([O-])O>>CCOc1cc(NC(C)=O)c([N+](=O)[O-])cc1C(=O)OC,,CC(=O)O,,CC(=O)OC(C)=O,,test
US06737425B1,BrCCBr.Oc1ccc2c(c1)OCO2>>BrCCOc1ccc2c(c1)OCO2,,O,,[Na+].[OH-],,test
US20110257137A1,O=C(Cc1cccs1)NNc1nc2cc(Cl)ccc2nc1Cl>>Clc1ccc2nc(Cl)c3nnc(Cc4cccs4)n3c2c1,,O=P(Cl)(Cl)Cl,,,,test
US20130150368A1,BrBr.CC(C)(CNc1nccn[n+]1[O-])c1ccc(F)cc1>>CC(C)(CNc1ncc(Br)n[n+]1[O-])c1ccc(F)cc1,,CC#N,,ClCCl,,test
US20090005356A1,Brc1cnc2[nH]ccc2c1.O=C(OO)c1cccc(Cl)c1>>O=C([O-])c1cccc(Cl)c1.O[n+]1cc(Br)cc2cc[nH]c21,,CN1CCCC1=O,,CCOCC,,test
US20030144301A1,COC(=O)c1ccc(C#CCCCC2(S(=O)(=O)c3ccc(OC)cc3)SC(=O)NC2=O)c(C)c1>>COc1ccc(S(=O)(=O)C2(CCCC#Cc3ccc(C(=O)O)cc3C)SC(=O)NC2=O)cc1,,C1CCOC1,CO,O,[Li+].[OH-],test
US04616014,CSc1nnc(-c2ccccc2)c(C)n1.O=C(c1ccco1)N1CCNCC1>>Cc1nc(N2CCN(C(=O)c3ccco3)CC2)nnc1-c1ccccc1,,CCOC(C)=O,c1ccccc1,,,test
US05142056,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)NC(Cc1ccccc1)C(O)C(Cc1ccccc1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C>>CC(C)[C@H](N)C(=O)NC(Cc1ccccc1)C(O)C(Cc1ccccc1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C,,ClC(Cl)Cl,,,,test
US20060276515A1,CS(=O)(=O)c1ccc(/C(=C/C#N)c2ccc(F)cc2)cc1>>CS(=O)(=O)c1ccc(C(CCN)c2ccc(F)cc2)cc1,,CC(=O)O,,,,test
US20100075976A1,CNCCN1CCN(c2nccnc2-c2ccc(F)cc2)CC1.ClCCl.Cn1cnc(S(=O)(=O)Cl)c1>>CN(CCN1CCN(c2nccnc2-c2ccc(F)cc2)CC1)S(=O)(=O)c1cn(C)cn1.Cl,,ClCCl,,CCN(CC)CC,,test
US20050137187A1,COC(CCn1cc2ccc(N)cc2n1)OC.O=C=Nc1ccc(Oc2ccccc2)cc1>>COC(CCn1cc2ccc(NC(=O)Nc3ccc(Oc4ccccc4)cc3)cc2n1)OC,,C1CCOC1,,,,test
US20080167287A1,CC(c1ccc2ncccc2c1)C(Cl)C=O.Nc1ncc(-c2ccc(Br)c(F)c2)nn1>>CC(c1ccc2ncccc2c1)c1cnc2ncc(-c3ccc(Br)c(F)c3)nn12,,CC(C)O,,CCN(CC)CC,,test
US20140336106A1,COc1ccc([C@@H](O)[C@H](NC(=O)[C@@H](N)CO)C(=O)OCc2ccccc2)cc1.O=C(O)CN1CCOCC1>>COc1ccc([C@@H](O)[C@H](NC(=O)[C@H](CO)NC(=O)CN2CCOCC2)C(=O)OCc2ccccc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120214769A1,CC1(C)OC(=O)CC(=O)O1.COC(=O)c1ccc(C(=O)O)cc1>>COC(=O)c1ccc(C(=O)C2C(=O)OC(C)(C)OC2=O)cc1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20090018103A1,CC(=O)Cl.CC(C)(C)OC(=O)N1CCC[C@@H]([C@@H](OCCN)c2cccc(Cl)c2F)C1>>CC(=O)NCCO[C@@H](c1cccc(Cl)c1F)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1,,CCN(CC)CC,,,,test
US20080280903A1,Cc1ccc(C(=O)CBr)cc1.c1ccncc1>>Cc1ccc(C(=O)C[n+]2ccccc2)cc1.[Br-],,CC(C)=O,,,,test
US20090227648A1,Fc1ccc(CBr)cc1.Nc1cccc(Br)c1>>Fc1ccc(CNc2cccc(Br)c2)cc1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04667007,CCCC[Sn](=O)CCCC.O=C(O)CCCCC(=O)O>>CCCC[Sn+2]CCCC.O=C([O-])CCCCC(=O)[O-],,O,,Cc1ccccc1,,test
US20120071479A1,COC(=O)C(Oc1ccc(CCC(=O)OCc2ccccc2)cc1)C(=O)N(C)CCO>>COC(=O)C(Oc1ccc(CCC(=O)O)cc1)C(=O)N(C)CCO,[Pd],CO,,,,test
US20130072492A1,CC(C)(C)ON=O.CC1(C(=O)NN)C(=O)Nc2nc(-c3nn(CCC(F)(F)C(F)(F)F)c4cc(Cl)ccc34)nc(N)c21>>CC1(C(=O)N=[N+]=[N-])C(=O)Nc2nc(-c3nn(CCC(F)(F)C(F)(F)F)c4cc(Cl)ccc34)nc(N)c21,,C1CCOC1,,O=C(O)C(F)(F)F,,test
US20070135464A1,C1CCOC1.CCO.O=C=NC(c1ccccc1)(c1ccccc1)c1ccccc1>>CN1CCCCC1CO,,C1CCOC1,,NN,,test
US20070135490A1,OCCC#Cc1c(Cl)cccc1Cl>>OCCCCc1c(Cl)cccc1Cl,O=[Pt]=O,CCO,CCOC(C)=O,,,test
US20110038876A1,CC(C)(C)OC(=O)N1CCC(c2ncc3cc4c(cc3n2)c(Br)nn4C(c2ccccc2)(c2ccccc2)c2ccccc2)C1>>Brc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc3cnc(C4CCNC4)nc3cc12,,C1COCCO1,,Cl,,test
US05444059,Cc1nc(Cl)c(Cl)n1CCCCN1CCN(c2ncc(OCc3ccccc3)cn2)CC1>>Cc1nc(Cl)c(Cl)n1CCCCN1CCN(c2ncc(O)cn2)CC1,[Pd],CO,,,,test
US20090286790A1,C/C=C/C=O.Cc1ccc([S@@](N)=O)cc1>>C/C=C/C=N/S(=O)c1ccc(C)cc1,,ClCCl,,O,,test
US20060009453A1,CN1CCN(Cc2ccc(C(F)(F)F)cc2[N+](=O)[O-])CC1>>CN1CCN(Cc2ccc(C(F)(F)F)cc2N)CC1,[Pd],CO,,,,test
US07518000B2,CC(C)(C)OC(=O)n1nc(-c2cc3ccc(OCCCN4CCCCC4)cc3n2C(=O)OC(C)(C)C)c2sc(COS(C)(=O)=O)cc21.OC1CCNCC1>>OC1CCN(Cc2cc3[nH]nc(-c4cc5ccc(OCCCN6CCCCC6)cc5[nH]4)c3s2)CC1,,ClCCl,,CCN(CC)CC,,test
US20100234365A1,O=C(N[C@@H](CO)c1cccc(C(F)(F)F)c1)OCc1ccccc1>>N[C@@H](CO)c1cccc(C(F)(F)F)c1,[Pd],CO,,,,test
US20100240702A1,CC(C)(C)OC(=O)C(C)(C)n1c(=O)[nH]c2ccccc21.Cc1cccc2c1c(C[N+](C)(C)C)cn2C>>Cc1cccc2c1C(Cn1c(=O)n(C(C)(C)C(=O)OC(C)(C)C)c3ccccc31)CN2C,,CCOC(C)=O,CN(C)C=O,[I-].[K+],,test
US20050250810A1,CCI.CN(Cc1cc2ccccc2[nH]1)C(=O)OCc1ccccc1>>CCn1c(CN(C)C(=O)OCc2ccccc2)cc2ccccc21,,CN(C)C=O,O,[H-].[Na+],,test
US20030171418A1,C#CCOc1ccc2cnn(C[C@H](C)NC(=O)OCc3ccccc3)c2c1>>C[C@@H](Cn1ncc2ccc3c(c21)C=CCO3)NC(=O)OCc1ccccc1,,Cc1cc(C)cc(C)c1,,,,test
US20070275984A1,CCOC(=O)c1cc2c(I)ccnc2s1.NCCc1ccccc1>>CCOC(=O)c1cc2c(NCCc3ccccc3)ccnc2s1,,CC#N,,CCN(CC)CC,O,test
US20090274947A1,CC(=O)OC(C)=O.CC1(C)CC(N)(C#N)CC(C)(C)N1>>CC(=O)NC1(C#N)CC(C)(C)NC(C)(C)C1,,ClC(Cl)Cl,,,,test
US20160185778A1,CC(C)(C)OC(=O)N1CCc2[nH]nc(C3(C)CCC3)c2C1.O=C=Nc1cccc(Cl)c1>>CC1(c2n[nH]c3c2CN(C(=O)Nc2cccc(Cl)c2)CC3)CCC1,,C1COCCO1,Cl,,,test
US20080039452A1,COC(=O)c1ccc(C(=O)N[C@@H]2CCCC[C@@H]2C(=O)N2CC[C@@H]3[C@H](c4ccccc4)Nc4ccccc4[C@@H]32)cc1>>O=C(O)c1ccc(C(=O)N[C@@H]2CCCC[C@@H]2C(=O)N2CC[C@@H]3[C@H](c4ccccc4)Nc4ccccc4[C@@H]32)cc1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20070197558A1,Cn1ccc(NC=C2C(=O)OC(C)(C)OC2=O)n1>>Cn1cc2c(=O)cc[nH]c2n1,,CC(C)=O,,c1ccc(Oc2ccccc2)cc1,,test
US20050171350A1,CCOc1nc(OC)c(C=O)c(OCC(F)(F)F)n1.O=C(N1CCN2[C@H](CNC[C@H]2C(c2ccccc2)c2ccccc2)C1)C(F)(F)F>>CCOc1nc(OC)c(CN2C[C@@H]3CN(C(=O)C(F)(F)F)CCN3[C@H](C(c3ccccc3)c3ccccc3)C2)c(OCC(F)(F)F)n1,,ClCCl,,O=C([O-])O.[Na+],,test
US20070010537A1,CI.CN(C(=O)Cc1cccc([N+](=O)[O-])c1)c1ccccc1>>CC(C(=O)N(C)c1ccccc1)c1cccc([N+](=O)[O-])c1,,C1CCOC1,,O,[H-].[Na+],test
US20070244119A1,CCCN(c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)cc(-n2cc(C(C)=O)nn2)c1)S(C)(=O)=O.[Li]Cc1ccccc1>>CCCN(c1cc(C(=O)N[C@H](C)c2ccc(F)cc2)cc(-n2cc(C(C)(O)Cc3ccccc3)nn2)c1)S(C)(=O)=O,,CCOCC,,C1CCOC1,,test
US20120142671A1,CC(C)(C)OC(=O)NC(CC(F)(F)F)C(N)=O.Cl>>Cl.NC(=O)C(N)CC(F)(F)F,,C1COCCO1,,,,test
US04957928,C[Si](C)(C)Cl.O=C1CCN(CCC2COc3ccccc3C2)CC1>>C[Si](C)(C)OC1=CCN(CCC2COc3ccccc3C2)CC1,,C1CCOC1,CCCCCC,CC(C)NC(C)C,[Li]CCCC,test
US20120288492A1,CSc1cnc(-c2ccc(NC(=S)Nc3ccccc3N)cc2)nc1N1CCOCC1>>CSc1cnc(-c2ccc(Nc3nc4ccccc4[nH]3)cc2)nc1N1CCOCC1,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20090209755A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1=N[C@@]2(c3cc(Cl)cc(Br)c3)CCC[C@H]2CS1>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1=N[C@@]2(c3cc(Cl)cc(Br)c3)CCC[C@H]2CS1,CN(C)c1ccncc1,ClCCl,,,,test
US03947374,Clc1nc(Cl)nc(Cl)n1.OCCNCCO>>OCCN(CCO)c1nc(Cl)nc(Cl)n1,,CC(C)=O,,O=C([O-])O.[Na+],,test
US20110046133A1,CC(C)(C)c1ccc(N)cc1.Nc1ccc(C(=O)O)cc1[N+](=O)[O-]>>CC(C)(C)c1ccc(NC(=O)c2ccc(N)c([N+](=O)[O-])c2)cc1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04241069,C=O.CNC.Cl.O=C1CC(c2ccccc2)Oc2ccccc21>>CN(C)CC1C(=O)c2ccccc2OC1c1ccccc1.Cl,,CC(C)O,,Cl,,test
US20110275638A1,CNCc1ccccc1.O=C(N[C@@H](Cc1ccc(O)cc1)C(=O)O)OCc1ccncc1>>CN(Cc1ccccc1)C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccncc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20090221555A1,CCN1CC2OC(C1)c1cc([N+](=O)[O-])ccc12>>CCN1CC2OC(C1)c1cc(N)ccc12,[Pd],CCO,ClCCl,[H][H],,test
US20130158056A1,Cc1nc(C)c(CNc2nc(S(C)(=O)=O)nc(Cl)c2C)s1.OCCCc1ccc2ccccc2n1>>Cc1nc(C)c(CNc2nc(OCCCc3ccc4ccccc4n3)nc(Cl)c2C)s1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20140045872A1,Cc1ccncc1I.O=C1NCCc2c(Cl)cccc21>>Cc1ccncc1N1CCc2c(Cl)cccc2C1=O,I[Cu]I,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20020045614A1,COc1cc2nc(N(C)CC3(c4ccccc4)CCNCC3)nc(N)c2cc1OC.Clc1ccccn1>>COc1cc2nc(N(C)CC3(c4ccccc4)CCN(c4ccccn4)CC3)nc(N)c2cc1OC,,CN1CCCC1=O,O,,,test
US20030236286A1,CC(C)(O)C(Cl)(Cl)Cl.O.Oc1ccccc1>>CC(C)(Oc1ccccc1)C(=O)O,,CC(C)=O,O,Cl,[Na+].[OH-],test
US20150018566A1,COc1ccc(C2=CC(O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)CCc3c2cc(OC)c(OC)c3OC)cc1O[Si](C)(C)C(C)(C)C>>COc1ccc(C2=CC(O)CCc3c2cc(OC)c(OC)c3OC)cc1O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05594141,Cc1ccnc(O)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1ccnc(S(=O)(=O)C(F)(F)F)c1,,c1ccncc1,,,,test
US05569786,COc1cc(CBr)cc(OC)c1OC.c1ccc([PH+](c2ccccc2)c2ccccc2)cc1>>COc1cc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc(OC)c1OC.[Br-],,Cc1ccccc1,,,,test
US20040132748A1,CCCCO.Nc1nc(Cl)nc2nc[nH]c12>>CCCCOc1nc(N)c2[nH]cnc2n1,,O,,[Na],,test
US20130059853A1,CCI.COc1ccc(-c2cccc3c2CCC3=O)c(OC)c1O>>CCOc1c(OC)ccc(-c2cccc3c2CCC3=O)c1OC,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080015246A1,CCOC(=O)c1ccc(-c2ccc(OCCCCO)c(-c3ccc(NCCC(C)=O)c(C(C)(C)C)c3)c2)cc1>>CC(=O)CCNc1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCCO)cc1C(C)(C)C,,C1CCOC1,O,[Na+].[OH-],,test
US20130217680A1,COC(=O)Cc1ccccc1O.O=C1CCC(=O)N1Br>>COC(=O)Cc1cccc(Br)c1O,,ClCCl,,CC(C)NC(C)C,,test
US20020151715A1,CC(=O)O.CCOC(=O)C[N+](=O)[O-].CCOC(OCC)OCC.Nc1ccc2c(c1)OC(F)(F)O2>>OCc1cn(-c2ccc3c(c2)OC(F)(F)O3)cn1,[Fe],,,,,test
US05455267,CC(C)(C)OC(=O)N(CC(=O)O)C(=O)OC(C)(C)C.CCC(CC)Oc1cc2oc(Sc3ccc(O)cc3)cc(=O)c2c(OC)c1OC.Cl>>CCC(CC)Oc1cc2oc(Sc3ccc(OC(=O)CN)cc3)cc(=O)c2c(OC)c1OC.Cl,,CCOC(C)=O,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05076832,CCN.O=C(Nc1cccc(C(F)(F)F)c1)C(Cl)c1ccccc1>>CCNC(C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1,,CCCCCC,CCOC(C)=O,[I-].[K+],,test
US20130158042A1,CC1(C)CN(C(=O)c2cccc(C3=CCOCC3)n2)CCN1C(=O)c1ncn(-c2cccc(Cl)c2)n1>>CC1(C)CN(C(=O)c2cccc(C3CCOCC3)n2)CCN1C(=O)c1ncn(-c2cccc(Cl)c2)n1,[Pd],CCOC(C)=O,,,,test
US20100113510A1,C[C@@](C(=O)O[C@H]1CN2CCC1CC2)(c1ccccc1)N1CCCCC1.O=C(CBr)Nc1ccon1>>C[C@@](C(=O)O[C@H]1C[N+]2(CC(=O)Nc3ccon3)CCC1CC2)(c1ccccc1)N1CCCCC1.[Br-],,CC#N,,,,test
US20130252934A1,CC(C)(C)OC(=O)n1c(C(O)CO)cc2ccccc21.CC(C)(C)[Si](C)(C)Cl>>CC(C)(C)OC(=O)n1c(C(O)CO[Si](C)(C)C(C)(C)C)cc2ccccc21,,ClCCl,ClCCl,c1c[nH]cn1,,test
US04186205,CSc1ccc(C(=O)C(Cl)c2ccc(SC)cc2)cc1.NC1=NCCC1>>CSc1ccc(-c2nc3n(c2-c2ccc(SC)cc2)CCC3)cc1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20030008227A1,CCCCCCCCCCCC(=O)OCC[N+](C)(C)Cc1ccccc1.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCCCCCCCCCC(=O)OCC[N+](C)(C)Cc1ccccc1.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,CO,O,[Cl-].[Na+],,test
US04303656,CN(C)CC1C=C(c2ccc(Cl)cc2)c2ccccc2O1>>CN(C)CC1CC(c2ccc(Cl)cc2)c2ccccc2O1,O=[Pt]=O,CCO,,[H][H],,test
US05654298,CNc1cc(N2CCc3ccccc32)cc(C)n1>>CNc1cc(-n2ccc3ccccc32)cc(C)n1,[Pd],CCOCC,,c1ccc(Oc2ccccc2)cc1,,test
US04726941,N#CN.O=C(Cl)C12CC3CC(CC(C3)C1)C2>>N#CNC(=O)C12CC3CC(CC(C3)C1)C2,,C1CCOC1,,[Na],,test
US20040077667A1,Cl.O=c1[nH]c(CCCN2CC=C(c3ccccc3)CC2)nc2ccccc12>>Cl.O=c1[nH]c(CCCN2CC=C(c3ccccc3)CC2)nc2ccccc12,,CCOC(C)=O,,ClC(Cl)Cl,,test
US20110046169A1,Nc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3c2)cc1.O=C(O)c1cccn(-c2ccc(F)cc2)c1=O>>O=C(Nc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3c2)cc1)c1cccn(-c2ccc(F)cc2)c1=O,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140005166A1,CC(C)(C)OC(=O)N1CCC(O)CC1.FC(F)(F)c1cccc(Cl)n1>>CC(C)(C)OC(=O)N1CCC(Oc2cccc(C(F)(F)F)n2)CC1,,C1CCOC1,,[H-].[Na+],,test
US20050261324A1,CC(C)=O.Nc1cncnc1>>CC(C)Nc1cncnc1,O=[Pt]=O,CCO,,[H][H],,test
US04730008,CCCO.O=C(O)c1ccc(I)cc1>>CCCOC(=O)c1ccc(I)cc1,CN(C)c1ccncc1,CCCO,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20010034343A1,COC(=O)c1cc(OCC(C)=O)ccc1OC>>COc1ccc(OCC(C)=O)cc1C(=O)O,,CO,,Cl,[Na+].[OH-],test
US05051422,CC(=O)Nc1cccc(N)c1.Cl.ClCCNCc1ccccc1>>CC(=O)Nc1cccc(NCCNCc2ccccc2)c1.Cl,,CC(C)O,,,,test
US20120172369A1,COC(=O)c1cccc(OCC2CCNCC2)c1.O=[N+]([O-])c1cnc(Cl)nc1>>COC(=O)c1cccc(OCC2CCN(c3ncc([N+](=O)[O-])cn3)CC2)c1,,O,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20100298324A1,COc1ccc(-n2c(=S)[nH]c3cc(C(=O)O)cc(Cl)c3c2=O)nc1OC.NCc1ccc(Cl)cc1>>COc1ccc(-n2c(=S)[nH]c3cc(C(=O)NCc4ccc(Cl)cc4)cc(Cl)c3c2=O)nc1OC,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090325928A1,COC(=O)[C@H]1C[C@H](O)C1.Clc1ncnc2[nH]cc(I)c12>>COC(=O)[C@@H]1C[C@H](n2cc(I)c3c(Cl)ncnc32)C1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130023523A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.CCOC(=O)c1cnc(SC)nc1Cl>>C=C(OCC)c1nc(SC)ncc1C(=O)OCC,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,[F-].[K+],,test
US06514968B1,BrCCOc1cccc2c1c1ccccc1n2Cc1ccccc1.NCc1ccccn1>>c1ccc(Cn2c3ccccc3c3c(OCCNCc4ccccn4)cccc32)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20160002205A1,Fc1cc(CBr)ccc1Cl.c1cn[nH]c1>>Fc1cc(Cn2cccn2)ccc1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05492912,C=O.CCOC(=O)C1CNCCN1Cc1ccccc1Cl>>CCOC(=O)C1CN(C)CCN1Cc1ccccc1Cl,,O=CO,,CO,,test
US06127546,CC(=O)OC(C)=O.CCN(CC)CC.ClCCl.O=C(Cl)c1ccccc1.c1ccncc1>>CC(=O)OCC=CC(NC(=O)c1ccccc1)c1ccccc1,,O,,,,test
US20080280875A1,FC1CNC1.O=C(O)c1ncc(F)cc1F>>O=C(c1ncc(F)cc1F)N1CC(F)C1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090156612A1,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C[C@H]1CCOc1ccc2c(c1)CCC(=O)N2.COCCCBr>>COCCCN1C(=O)CCc2cc(OCC[C@@H]3CN(C(=O)OCc4ccccc4)CCN3C(=O)OC(C)(C)C)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20140364432A1,COCCN(CCOC)S(F)(F)F.O=C(NC[C@@H]1C[C@@H](O)CN1C(=O)c1ccccc1-c1ccccc1)c1cccc2cccnc12>>O=C(NC[C@@H]1C[C@H](F)CN1C(=O)c1ccccc1-c1ccccc1)c1cccc2cccnc12,,ClCCl,,,,test
US20150011533A1,Nc1c[nH]c2ncc(Cl)c(F)c12.O=C(O)c1cnn(Cc2ccccc2)c1>>O=C(Nc1c[nH]c2ncc(Cl)c(F)c12)c1cnn(Cc2ccccc2)c1,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100240702A1,CI.COC(=O)c1cc(Br)cc2cc[nH]c12>>COC(=O)c1cc(Br)cc2ccn(C)c12,,CN(C)C=O,,[H-].[Na+],,test
US20150266868A1,Nc1nccc(Cl)c1[N+](=O)[O-].O=C1CCC(=O)N1Cl>>Nc1ncc(Cl)c(Cl)c1[N+](=O)[O-],,CC#N,,,,test
US20100190768A1,C=CCC(O)(c1cn(Cc2ccccc2)c2cc([N+](=O)[O-])ccc12)C(F)(F)F.O=[O+][O-]>>O=CCC(O)(c1cn(Cc2ccccc2)c2cc([N+](=O)[O-])ccc12)C(F)(F)F,,CO,,,,test
US20120329797A1,NCc1cccs1.O=C(O)c1ccc2cccnc2c1O>>O=C(NCc1cccs1)c1ccc2cccnc2c1O,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US03966816,CCNCC.O=[N+]([O-])c1cc(C(F)(F)F)c(Cl)c([N+](=O)[O-])c1Cl>>CCN(CC)c1c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c1[N+](=O)[O-],,CCO,,,,test
US20040209905A1,COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.NCc1ccc(F)cc1F.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2ncnc(Oc3ccc(NC(=O)NCc4ccc(F)cc4F)cc3)c2cc1OC,,CCN(CC)CC,ClC(Cl)Cl,CO,,test
US20140171446A1,Cc1ccncc1C(=O)O.Nc1cnc(Br)cn1>>Cc1ccncc1C(=O)Nc1cnc(Br)cn1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20090264445A1,COC(=O)C(CC(F)F)N1CC(Oc2ccccc2Cl)=CC1=O>>O=C(O)C(CC(F)F)N1CC(Oc2ccccc2Cl)=CC1=O,,O,,C1CCOC1,[Li+].[OH-],test
US20050107354A1,COCOc1cc(O)ccc1CCNS(=O)(=O)c1cc(C#N)ccc1OC.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COCOc1cc(OS(=O)(=O)C(F)(F)F)ccc1CCNS(=O)(=O)c1cc(C#N)ccc1OC,,ClCCl,,,,test
US04942173,CCCC12COC(c3ccc(C#C[Si](C)(C)C)cc3)(OC1)OC2C(F)(F)F>>C#Cc1ccc(C23OCC(CCC)(CO2)C(C(F)(F)F)O3)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150299190A1,COC(=O)c1ccc(N2CCOCS2(=O)=O)cc1F>>O=C(O)c1ccc(N2CCOCS2(=O)=O)cc1F,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20080242706A1,O=c1cc(C(F)F)n(CC2CC2)cc1OCc1ccccc1>>O=c1cc(C(F)F)n(CC2CC2)cc1O,[Pd],CO,,[H][H],,test
US20110288069A1,CC(C)(C)OC(=O)N1CCN2c3ncccc3NC(=O)CC2C1.O=C(Cl)c1ccc(F)cc1>>O=C1CC2CN(C(=O)c3ccc(F)cc3)CCN2c2ncccc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060270671A1,CC(C)(C)OC(=O)NCC(=O)c1cc2ccccc2s1.Cl>>Cl.NCC(=O)c1cc2ccccc2s1,,C1COCCO1,,CCOC(C)=O,,test
US20040192728A1,CC(C)(C)OC(=O)Nc1cnc2ccc(F)cc2c1>>Nc1cnc2ccc(F)cc2c1,,ClCCCl,,O,O=C(O)C(F)(F)F,test
US20140329807A1,CS(=O)(=O)OCl.N[C@@H]1CC[C@@H](Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1>>CS(=O)(=O)N[C@@H]1CC[C@@H](Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1,,CO,CS(C)=O,CCN(C(C)C)C(C)C,ClCCl,test
US20060074102A1,CC(C)(C)OC(=O)NNC(=O)c1cc2c(Oc3ccc(-c4cc(Cl)cc(Cl)c4)cc3)cncc2s1>>NNC(=O)c1cc2c(Oc3ccc(-c4cc(Cl)cc(Cl)c4)cc3)cncc2s1,,CCOCC,,O=C(O)C(F)(F)F,,test
US04147780,CC(C)C=O.NC(c1ccccc1)c1ccccc1>>CC(C)C=NC(c1ccccc1)c1ccccc1,,O,,c1ccccc1,,test
US20070259881A1,C=CCn1c(COCC)nc2c(Cl)nc3ccccc3c21.C=O.ONCc1ccccc1>>CCOCc1nc2c(Cl)nc3ccccc3c2n1CC1CCN(Cc2ccccc2)O1,,Cc1ccccc1,,Cl,O=C([O-])O.[Na+],test
US20120277224A1,CCOC(=O)CC(=O)c1ccc2[nH]nnc2c1.Nc1n[nH]c(N)c1-c1ccccn1>>Nc1nn2c(=O)cc(-c3ccc4[nH]nnc4c3)[nH]c2c1-c1ccccn1,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100137250A1,CCOC(=O)Cc1cc(C(=O)c2ccc(S(=O)(=O)N3CCN(C(=O)OCC)CC3)cc2)c2cc(F)ccc2c1>>CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C(=O)c3cc(CC(=O)O)cc4ccc(F)cc34)cc2)CC1,,C1CCOC1,O,[Li+].[OH-],,test
US20060046999A1,COc1ccc(N)c(OC)c1.N#CCC(=O)c1ccc(F)cc1>>COc1ccc(NC(=N)CC(=O)c2ccc(F)cc2)c(OC)c1,,CCO,,,,test
US20080275041A1,N#Cc1ccc2c(c1)NC(=O)C2.O=C1CN(Cc2ccc(Cl)[n+]([O-])c2)CCN1>>N#Cc1ccc2c(-c3ccc(CN4CCNC(=O)C4)c[n+]3[O-])c(O)[nH]c2c1,,CN1CCCC1=O,,[H-].[Na+],,test
US20040229861A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)CNC1=O>>N[C@@H]1CC[C@@H](c2cccc(F)c2F)CNC1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130059853A1,CCI.COc1c(OC(F)F)ccc(-c2cccc3c2CCC3=O)c1O>>CCOc1c(-c2cccc3c2CCC3=O)ccc(OC(F)F)c1OC,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090176858A1,C=CCCC(C)(C)COC(=O)Cl.COC(=O)C(N)CNC(=O)OC(C)(C)C>>C=CCCC(C)(C)COC(=O)NC(CNC(=O)OC(C)(C)C)C(=O)OC,,C1CCOC1,,CCN(CC)CC,Cl,test
US20150252030A1,COC(=O)CBr.Cc1cc(Cl)cc(C)c1O>>COC(=O)COc1c(C)cc(Cl)cc1C,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130190522A1,CC[C@@H](c1cccc(OS(=O)(=O)c2ccc(C)cc2)c1)[C@@H](C)CN(C)C.O=C(O)C(=O)O>>CC[C@@H](c1cccc(OS(=O)(=O)c2ccc(C)cc2)c1)[C@@H](C)CN(C)C.O=C(O)C(=O)O,,CO,,O,O,test
US20100009969A1,CC1CCCN1.Cc1ccc(S(=O)(=O)N2Cc3nc(-c4ccc(OCCCCl)cc4)sc3C2)cc1>>Cc1ccc(S(=O)(=O)N2Cc3nc(-c4ccc(OCCCN5CCCC5C)cc4)sc3C2)cc1,,CC#N,,,,test
US20100267634A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCN[C@@H](C(=O)O)c1ccccc1>>CCN(C(=O)OC(C)(C)C)[C@@H](C(=O)O)c1ccccc1,,CO,,CCN(C(C)C)C(C)C,,test
US04211723,N.O=C(Cl)c1ccccc1S(=O)(=O)Cl>>O=C1NS(=O)(=O)c2ccccc21,,CO,,O,,test
US05162316,CCCOc1ccccc1-c1nc2nc(NN)ncc2c(=O)[nH]1>>CCCOc1ccccc1-c1nc2ncncc2c(=O)[nH]1,O=[Ag],CO,,,,test
US20160108016A1,COc1cc(CC(=O)Cl)cc(OC)c1.O=C1N[C@H](Cc2ccccc2)CO1>>COc1cc(CC(=O)N2C(=O)OC[C@H]2Cc2ccccc2)cc(OC)c1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20060160864A1,CCCCOCCOc1ccc(-c2cnc(N3CCCC3)c(C=O)c2)cc1.CCOC(=O)CP(=O)(OCC)OCC>>CCCCOCCOc1ccc(-c2cnc(N3CCCC3)c(/C=C/C(=O)OCC)c2)cc1,,Cc1ccccc1,,[H-].[Na+],,test
US20020156081A1,CC(C)(C)OC(=O)N1CCC(O)C1.Nc1ncnc2[nH]nc(I)c12>>CC(C)(C)OC(=O)N1CCC(n2nc(I)c3c(N)ncnc32)C1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04458078,CCCCCCCCCCCCCCCCCC(=O)Cl.COC(=O)[C@@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)OC(C)(C)C.C[Si](C)(C)C(C(N)=O)[Si](C)(C)C.ClCCl>>CCCCCCCCCCCCCCCCCC(=O)N[C@@H](C)C(=O)N[C@H](CCC(=O)O)C(=O)OCc1ccccc1,,ClCCl,,O,,test
US20040142979A1,CCCCOc1ccc(-c2ccc(S(=O)(=O)C3(C(=O)OC(C)(C)C)CCOCC3)s2)cc1>>CCCCOc1ccc(-c2ccc(S(=O)(=O)C3(C(=O)O)CCOCC3)s2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140228361A1,C1COC2CNCC2O1.COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCCl>>COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CC2OCCOC2C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150210682A1,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCC3CCOCC3)cc1CC2CC>>CCC1Cc2cc(OCC3CCOCC3)c(OC)cc2-c2cc(=O)c(C(=O)O)cn21,,CO,O,[Li]O,,test
US20130131132A1,Cn1cnc(S(=O)(=O)NCCOc2ccc3c(c2)[C@H](Cc2ccccc2F)[C@H](N2C(=O)C4CC4C2=O)CC3)c1>>Cn1cnc(S(=O)(=O)NCCOc2ccc3c(c2)[C@H](Cc2ccccc2F)[C@H](N2CC4CC4C2)CC3)c1,,C1CCOC1,ClCCl,CO,,test
US20080167322A1,CC(C)C(CCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)NC(=O)CCOc1cc(-c2cc(Cl)cc(Cl)c2)nn1-c1ccc2ccccc2c1>>CC(C)C(CCCO)NC(=O)CCOc1cc(-c2cc(Cl)cc(Cl)c2)nn1-c1ccc2ccccc2c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140275028A1,CCOC(=O)C(C)(C)Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2[nH]1.ClCc1ccc2ccccc2c1>>CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc2ccccc2c1)C(=O)O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04734418,COc1cc2nc(Cl)nc(N)c2cc1OC.Cn1[nH]c2nc(N3CCNCC3)ncc2c1=O>>COc1cc2nc(N3CCN(c4ncc5c(=O)n(C)[nH]c5n4)CC3)nc(N)c2cc1OC.Cl,,CC(C)CCO,,CCO,,test
US04659365,Cc1cccc(OC(F)F)c1N.O=C(Cl)CCl>>Cc1cccc(OC(F)F)c1NC(=O)CCl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04418208,Cc1cc(N)ccc1Br.O=C(O)CN(CC(=O)O)CC(=O)O>>Cc1cc(NC(=O)CN(CC(=O)O)CC(=O)O)ccc1Br,,c1ccncc1,,CC(=O)OC(C)=O,,test
US20140315885A1,CC(C)(C)OC(=O)N1CCNCC1.Cc1cc(F)ncc1[N+](=O)[O-]>>Cc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ncc1[N+](=O)[O-],,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04728650,COc1c(C)c(C)c2c(c1C)CCC(C)(CCO)O2.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1c(C)c(C)c2c(c1C)CCC(C)(CCOS(=O)(=O)c1ccc(C)cc1)O2,,c1ccncc1,,Cl,,test
US06521627B1,CC(O)c1ncnc(Cl)c1I.NCCc1ccccc1>>CC(O)c1ncnc(NCCc2ccccc2)c1I,,Cc1ccccc1,,CCN(CC)CC,,test
US20030092694A1,C1CNCCN1.Fc1cc2nc(Cl)c(Cl)nc2cc1F>>Fc1cc2nc(Cl)c(N3CCNCC3)nc2cc1F,,CCO,,,,test
US20070191364A1,CCN(CC)C(=O)N(C1CCCCC1)C1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC2CCOCC2)CC1.Cl>>CCN(CC)C(=O)N(C1CCCCC1)C1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC2CCOCC2)CC1.Cl,,CCOCC,,,,test
US20150158878A1,CC(=O)Nc1cc2c(cc1[N+](=O)[O-])OC(F)(F)O2>>Nc1cc2c(cc1[N+](=O)[O-])OC(F)(F)O2,,CO,,CC(=O)O,C[O-].[Na+],test
US20040132994A1,Nc1c(N=O)cnn1CCF.O=S(=O)(O)O>>Nc1cnn(CCF)c1N.O=S(=O)(O)O,[Pd],CO,O,,,test
US20140121198A1,O=[N+]([O-])c1cnc2ccsc2c1N[C@@H]1CC[C@@H](O)CC1>>Nc1cnc2ccsc2c1N[C@@H]1CC[C@@H](O)CC1,[Pd],CO,,,,test
US20050124656A1,Cc1ccc(-c2cccc(C(=O)OC(C)(C)C)c2)cc1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)c1cccc(-c2ccc(CBr)cc2)c1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US05324747,CCCCCCCCCCCCCCCCCCOc1cc(OCCCCC(=O)OC)cc(N(CC(=O)OCc2ccccc2)CC(=O)OCc2ccccc2)c1>>CCCCCCCCCCCCCCCCCCOc1cc(OCCCCC(=O)OC)cc(N(CC(=O)O)CC(=O)O)c1,[Pd],C1CCOC1,,[H][H],,test
US20140121187A1,CCC(=O)Nc1ccc(C)c(C)c1.O=C1c2ccccc2C(=O)C1(O)O>>CCC(=O)Nc1cc(C)c(C)cc1C1(O)C(=O)c2ccccc2C1=O,,O=S(=O)(O)O,,,,test
US20030232832A1,COC(OC)N(C)C.Cc1nn2c(Cl)ccc2c(=O)n1Cc1ccccc1>>CN(C)C=Cc1nn2c(Cl)ccc2c(=O)n1Cc1ccccc1,,CN(C)C=O,,O=S(=O)([O-])[O-].[Mg+2],,test
US20140309193A1,COCCOCC(C)(C)C(=O)OC>>COCCOCC(C)(C)C(=O)O,,O,,[K+].[OH-],,test
US20030149029A1,COC(=O)c1ccc(OCCc2c(CCO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1OC>>COC(=O)c1ccc(OCCc2c(CCO)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1OC,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120214668A1,C#CCN1C(=O)C(F)(F)Oc2cc(F)c(N)cc21.O=C1OC(=O)C2=C1CCCC2>>C#CCN1C(=O)C(F)(F)Oc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc21,,CC(=O)O,,,,test
US04652566,Cl.NC(=O)c1cc2cccc(OCC3CO3)c2o1>>NC(=O)c1cc2cccc(OCC(O)CCl)c2o1,,ClC(Cl)Cl,,,,test
US20080058340A1,O=C(n1ccnc1)n1ccnc1.O=[N+]([O-])c1c(F)cc(F)c(F)c1Nc1ccc(I)cc1F>>O=c1[nH]c2c(F)cc(F)c(F)c2n1-c1ccc(I)cc1F,,ClCCl,,,,test
US04459232,Nc1ccccc1Cc1ncc[nH]1.S=C(Cl)Cl>>S=C1Nc2ccccc2Cc2nccn21,,ClC(Cl)(Cl)Cl,,CCN(CC)CC,ClCCl,test
US20040220177A1,Fc1cnc(Cl)nc1NCc1ccccn1.Nc1ccc2[nH]ncc2c1>>Fc1cnc(Nc2ccc3[nH]ncc3c2)nc1NCc1ccccn1,,CO,,,,test
US20020055631A1,COC(=O)Cl.Nc1cc(F)ccc1-c1ccc(C(=O)NS(=O)(=O)c2ccc(NCC34CC5CC(CC(C5)C3)C4)c([N+](=O)[O-])c2)cc1>>COC(=O)Nc1cc(F)ccc1-c1ccc(C(=O)NS(=O)(=O)c2ccc(NCC34CC5CC(CC(C5)C3)C4)c([N+](=O)[O-])c2)cc1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20150344480A1,Cn1nc(-c2ccc(F)cc2)cc1C1=CCOCC1>>Cn1nc(-c2ccc(F)cc2)cc1C1CCOCC1,[Pd],CO,,[H][H],,test
US04997840,CS(=O)(=O)Cl.Cn1cc(O)c(=O)c2ccc(F)cc21>>Cn1cc(OS(C)(=O)=O)c(=O)c2ccccc21,,O,,[Na+].[OH-],,test
US20160122344A1,COCCCOc1cc(CC(N)COC)ccc1OC.O=CO>>COCCCOc1cc(CC(COC)NC=O)ccc1OC,,C1COCCO1,,,,test
US20120165347A1,BrCc1ccc(Br)cc1I.CCOC(=O)C1CCC(C(F)(F)F)CC1>>CCOC(=O)C1(Cc2ccc(Br)cc2I)CCC(C(F)(F)F)CC1,,C1CCOC1,CCOC(C)=O,O,CC(C)[N-]C(C)C.[Li+],test
US20040029886A1,CC(=O)c1cc(OCC=C(Cl)Cl)cc(Cl)c1O.OCCCCOc1ccc(C(F)(F)F)cn1>>CC(=O)c1cc(OCC=C(Cl)Cl)cc(Cl)c1OCCCCOc1ccc(C(F)(F)F)cn1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05783572,COc1nc2cc(C)c(C)c(CCl)c2nc1OC.c1c[nH]cn1>>COc1nc2cc(C)c(C)c(Cn3ccnc3)c2nc1OC,,O,,,,test
US20120077793A1,CC(C)OC(=O)N1CCC(Oc2ccc(-c3ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)N4CCC(F)(F)C4)c(F)c3)cn2)CC1>>CC(C)OC(=O)N1CCC(Oc2ccc(-c3ccc(C[C@H](N)C(=O)N4CCC(F)(F)C4)c(F)c3)cn2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06034096,CC(C)Br.O=C(O)C1Cc2ccccc2CN1>>CC(C)N1Cc2ccccc2CC1C(=O)O,,CCO,,[Na+].[OH-],,test
US20090170911A1,CC(OC(=O)Nc1conc1-c1ccc(CCCl)cc1)c1ccccc1Cl.COC(=O)CS>>COC(=O)CSCCc1ccc(-c2nocc2NC(=O)OC(C)c2ccccc2Cl)cc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US05840732,CCCC=O.O=C1CSC(=O)N1CCCCS(=O)c1cccc2nccn12>>CCCC=C1SC(=O)N(CCCCS(=O)c2cccc3nccn23)C1=O,,CCO,,C1CCNCC1,,test
US04038328,Cc1cc(O)c(S(=O)(=O)O)cc1Cl.ClCl>>Cc1c(Cl)cc(S(=O)(=O)O)c(O)c1Cl,,O,O=S(=O)(O)O,,,test
US04937251,Brc1ccccn1.C#CCOCCCCCCNCc1ccccc1>>C(#Cc1ccccn1)COCCCCCCNCc1ccccc1,,O=C([O-])O,[Na+],CCNCC,,test
US04579848,Cc1cc(C#N)ccn1.[Cl-].[NH4+]>>Cc1cc(C(=N)N)ccn1.Cl,,CO,,C[O-].[Na+],,test
US20040138462A1,COc1cc(S(=O)(=O)c2ccc(CCNC(=O)C(F)(F)F)cc2)ccc1OCc1ccccc1>>COc1cc(S(=O)(=O)c2ccc(CCNC(=O)C(F)(F)F)cc2)ccc1O,[Pd],CO,,,,test
US20100331326A1,Cc1ccncc1N1CCNC1=O.Clc1nccc2sc(Br)cc12>>Cc1ccncc1N1CCN(c2cc3c(Cl)nccc3s2)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20150111882A1,C=CC1(O)CC(C)(C)Cc2sc(-c3cccc(Br)c3)cc21.NC(N)=S>>CC1(C)C/C(=C\CSC(=N)N)c2cc(-c3cccc(Br)c3)sc2C1,,CC(=O)O,CCOCC,,,test
US09428503B2,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=c1[nH]c2cnc3ccc(Br)cc3c2n1C1CCOCC1>>CC(C)(C)OC(=O)n1c(=O)n(C2CCOCC2)c2c3cc(Br)ccc3ncc21,,ClCCl,,CCN(CC)CC,,test
US20110201604A1,CN.CS(=O)(=O)c1ccc(F)c([N+](=O)[O-])c1>>CS(=O)(=O)c1ccc(CN)c([N+](=O)[O-])c1,,CN(C)C=O,,,,test
US20160075663A1,CCC(=O)c1ccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c2c1>>CC(O)c1ccc2nc(NC(=O)CC(C)(C)C)n(C3CCC3)c2c1,,CCOC(C)=O,,CCO,[BH4-].[Na+],test
US20160194290A1,CCCl.C[Si](C)(C)N=C=O.NCCCC(=O)O>>CCOC(=O)CCCNC(N)=O,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,CCOC(C)=O,test
US20160264548A1,C=CC(=O)Cl.NC(=O)c1cc(NC2CCNCC2)cnc1Oc1ccc(Oc2ccccc2)cc1>>C=CC(=O)N1CCC(Nc2cnc(Oc3ccc(Oc4ccccc4)cc3)c(C(N)=O)c2)CC1,,ClCCl,,CCN(CC)CC,,test
US20120245161A1,O=C(c1c[nH]c2cccc(Br)c12)C(F)(F)F.O=S(=O)(OCCOC(F)(F)F)C(F)(F)F>>O=C(c1cn(CCOC(F)(F)F)c2cccc(Br)c12)C(F)(F)F,,C1CCOC1,,[H-].[Na+],,test
US20130225600A1,BrBr.COC(=O)c1sccc1C>>COC(=O)c1scc(Br)c1C,[Zn],CC(=O)O,,[Na+].[OH-],,test
US20080161366A1,O=S1(=O)Nc2ccccc2N1c1ccc(F)c(F)c1F.OCCCBr>>O=S1(=O)N(CCCBr)c2ccccc2N1c1ccc(F)c(F)c1F,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060074115A1,COc1ccc(COC(c2cccc(O)c2)(C(F)(F)F)C(F)(F)F)cc1.c1ccc(C2CO2)cc1>>COc1ccc(COC(c2cccc(OCC(O)c3ccccc3)c2)(C(F)(F)F)C(F)(F)F)cc1,,C1COCCO1,CCOCC,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20080194556A1,CCOc1cc(F)c(C#N)c(F)c1.N>>CCOc1cc(N)c(C#N)c(F)c1,,CCO,,,,test
US20120202781A1,COC(=O)c1cc(Cc2ccc3c(c2)C[C@@H](NC(=O)OCc2ccccc2)C3)cc(C(F)(F)F)c1>>O=C(N[C@H]1Cc2ccc(Cc3cc(CO)cc(C(F)(F)F)c3)cc2C1)OCc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130053380A1,CC(C)(C)OC(=O)NC(CCCc1ccccc1CBr)Cc1ccccc1>>NC(CCCc1ccccc1CBr)Cc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080275043A1,COC(=O)c1ccc(Oc2cc(Cl)c(CC3CCN([C@H]4CC[C@@H](O[Si](C)(C)C(C)(C)C)CC4)C3=O)c(Cl)c2)cc1>>COC(=O)c1ccc(Oc2cc(Cl)c(CC3CCN(C4CCC(O)CC4)C3=O)c(Cl)c2)cc1,,CCO,,Cl,,test
US04540732,C=CC(=O)OC.CC(C)(C)c1cc(S)c(O)c(C(C)(C)C)c1>>COC(=O)CCSc1cc(C(C)(C)C)cc(C(C)(C)C)c1O,,CCN(CC)CC,,Cc1ccccc1,,test
US06403705B1,C#C[Si](C)(C)C.O=C(O)c1cc(I)ccc1I>>C[Si](C)(C)C#Cc1ccc(I)c(C(=O)O)c1,[Cu]I,,,,,test
US06028195,BrCc1ccccc1.COc1ccccc1N1CCN(C(=O)Nc2cc(C)c(C)nc2OC)CC1>>COc1ccccc1N1CCN(C(=O)N(Cc2ccccc2)c2cc(C)c(C)nc2OC)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20060229302A1,CCc1ccc2c3c1cc(C(=O)OC)n3CC(=O)CN2>>CCc1ccc2c3c1cc(C(=O)O)n3CC(=O)CN2,,CCO,,[Na+].[OH-],,test
US20090093524A1,C[Si](C)(C)C#CCO.[N-]=[N+]=Nc1c(Cl)cccc1Cl>>OCc1cnnn1-c1c(Cl)cccc1Cl,,Cc1ccccc1,ClCCl,,,test
US20110112062A1,CC(C)(C)OC(=O)N1CC[C@@H](Nc2ccc(F)cn2)C1>>Fc1ccc(N[C@@H]2CCNC2)nc1,,ClCCl,,C1COCCO1,Cl,test
US04511569,CC(=O)Cl.Nc1cc2c([nH]c1=O)CCc1ccccc1-2>>CC(=O)Nc1cc2c([nH]c1=O)CCc1ccccc1-2,,ClC(Cl)Cl,,c1ccncc1,,test
US20030078251A1,C1CCOC1.O=C=O.OCc1ccoc1>>COC(=O)c1occc1CO,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US06432993B1,CN(C(=O)OC(C)(C)C)c1cc(Oc2cccc(-c3ccccc3)c2)ccc1[N+](=O)[O-]>>CN(C(=O)OC(C)(C)C)c1cc(Oc2cccc(-c3ccccc3)c2)ccc1N,[Pd],CO,Cc1ccccc1,,,test
US20020128477A1,Fc1ccc2[nH]cc(Cc3ccncc3)c2c1>>Fc1ccc2[nH]cc(CC3CCNCC3)c2c1,O=[Pt]=O,CC(=O)O,CCO,,,test
US05051524,CCCC(O)P(=O)(CCCN)OCC>>CCCC(O)P(=O)(O)CCCN,,O,,Cl,,test
US20130150343A1,CCOC(OCC)OC(C)=O.NNc1ccc(F)cn1>>Fc1ccc2nncn2c1,,C1CCCCC1,,,,test
US20130053382A1,CC(C)(C)OC(=O)NCc1ccc(-c2cc(F)ccc2NC(=O)c2csc(-c3cnn(COCC[Si](C)(C)C)c3)n2)cc1.Cl>>Cl.NCc1ccc(-c2cc(F)ccc2NC(=O)c2csc(-c3cn[nH]c3)n2)cc1,,C1COCCO1,,,,test
US05387710,O=C1CCCCc2ccc([N+](=O)[O-])cc21>>O=[N+]([O-])c1ccc2c(c1)C(O)CCCC2,,CO,,[BH4-].[Na+],,test
US20040082607A1,CC(C)C(=O)Cl.CC(C)Cn1c(CNC(=O)OC(C)(C)C)c(-c2ccccc2)c2cc(CN)ccc2c1=O>>CC(C)Cn1c(CNC(=O)OC(C)(C)C)c(-c2ccccc2)c2cc(CNC(=O)C(C)C)ccc2c1=O,,C1CCOC1,,CCN(CC)CC,,test
US20060293348A1,CSc1nc(Cl)c(C=O)c(Cl)n1.Nc1c(F)cc(F)cc1F>>CSc1nc(Cl)c(C=O)c(Nc2c(F)cc(F)cc2F)n1,,ClC(Cl)Cl,,CCN(CC)CC,O=C([O-])[O-].[Na+].[Na+],test
US05508385,CCCCOC(OCCCC)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCC(=O)N1C(=O)OCc1ccccc1>>CCCCOC(OCCCC)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCC(=O)N1C(=O)OCc1ccccc1,,ClC(Cl)Cl,,Cl,,test
US20140206681A1,COC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Nc1nccn2c([C@@H]3CC[C@H]4CCC(=O)N4C3)nc(Br)c12>>COC(=O)c1ccc(-c2nc([C@@H]3CC[C@H]4CCC(=O)N4C3)n3ccnc(N)c23)cc1,,C1COCCO1,ClCCl,CO,O=C([O-])[O-].[K+].[K+],test
US04371537,CC(C)S(=O)(=O)c1ccc(S(=O)(=O)C(C)C)nc1.Oc1ccc(Cl)c(Cl)c1>>CC(C)S(=O)(=O)c1ccc(Oc2ccc(Cl)c(Cl)c2)nc1,,C1CCOC1,,O,CC(C)(C)[O-].[K+],test
US20090221555A1,CNC(=O)c1ccccc1NC.Fc1cnc(Cl)nc1Cl>>CNC(=O)c1ccccc1N(C)c1nc(Cl)ncc1F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04351839,BrCBr.CCC1CC(c2ccccc2)C(=O)O1>>CCC1CC(CBr)(c2ccccc2)C(=O)O1,,C1CCOC1,CN(C)P(=O)(N(C)C)N(C)C,CC(C)NC(C)C,[Li]CCCC,test
US20060052392A1,CCC(=O)Cl.Cc1cc2c(cc1C)C(CCO)N(c1cccnc1)C2=O>>CCC(=O)OCCC1c2cc(C)c(C)cc2C(=O)N1c1cccnc1,,ClCCl,,CCN(CC)CC,,test
US20070287699A1,COc1cc2c(=O)c(C#N)cn(Cc3ccc(Cl)cc3)c2cc1OC.NO>>COc1cc2c(=O)c(C(=N)NO)cn(Cc3ccc(Cl)cc3)c2cc1OC,,CCO,,,,test
US20040038239A1,C#CCCC(=O)O.CNC>>C#CCCC(=O)N(C)C,,ClCCl,,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US20040116465A1,CCOc1ccc(CC(=O)Nc2cc(C(=O)N(CC)CC)ccc2[N+](=O)[O-])cc1>>CCOc1ccc(CC(=O)Nc2cc(C(=O)N(CC)CC)ccc2N)cc1,[Pd],CCOC(C)=O,,,,test
US20130078214A1,CC(C)(CN)CNC(=O)OC(C)(C)C.O=C(O)c1ccc(Nc2cc(NCc3ccc(O)cc3)nc(OCC(F)(F)F)n2)nc1>>CC(C)(CNC(=O)OC(C)(C)C)CNC(=O)c1ccc(Nc2cc(NCc3ccc(O)cc3)nc(OCC(F)(F)F)n2)nc1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20130079313A1,CS(=O)(=O)Oc1cc(C(=O)O)ccc1OCC1CC1.O=C(CO)OCc1ccccc1>>CS(=O)(=O)Oc1cc(C(=O)OCC(=O)OCc2ccccc2)ccc1OCC1CC1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20150368249A1,Cc1cc(O)n2nc(OC(F)F)cc2n1.ClCc1ccc(Cl)nc1>>Cc1cc(=O)n2nc(OC(F)F)cc2n1Cc1ccc(Cl)nc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20140128606A1,Nc1ccc(Br)cc1.O=C(Cl)CCCCBr>>O=C(CCCCBr)Nc1ccc(Br)cc1,,ClCCl,,CCN(CC)CC,O=C([O-])[O-].[Na+].[Na+],test
US20130023502A1,CCOC(=O)c1cc2cc([N+](=O)[O-])cc(C)c2[nH]1>>CCOC(=O)c1cc2cc(N)cc(C)c2[nH]1,[Pd],C1CCOC1,CO,[H][H],,test
US04670465,BrCC#CCOC1CCCCO1.Oc1ccccc1>>C(#CCOC1CCCCO1)COc1ccccc1,,CCO,,O,[Na+].[OH-],test
US20050070441A1,CCN=C=O.Cc1cc(Oc2ccc(N)c(C(F)(F)F)c2)n[nH]1>>CCNC(=O)n1nc(Oc2ccc(N)c(C(F)(F)F)c2)cc1C,,CCOC(C)=O,,CCN(CC)CC,Cl,test
US20130012499A1,COC(=O)c1c(CN2CCC(N3CCCC3)CC2)c(-c2cccc(C(F)(F)F)c2)nc2ccc(S(C)(=O)=O)cc12>>CS(=O)(=O)c1ccc2nc(-c3cccc(C(F)(F)F)c3)c(CN3CCC(N4CCCC4)CC3)c(C(=O)O)c2c1,,CO,O,[K+].[OH-],,test
US20120010183A1,CS(=O)(=O)NC(=O)c1cc(Cl)c(Oc2cnc(F)c(Cl)c2)cc1F.Oc1ccccc1>>CS(=O)(=O)NC(=O)c1cc(Cl)c(Oc2cnc(Oc3ccccc3)c(Cl)c2)cc1F,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US08742107B1,Cl.N#Cc1[nH]c(=O)c(=O)[nH]c1C#N.O=S(Cl)Cl>>N#Cc1nc(Cl)c(Cl)nc1C#N,,CN(C)C=O,,,,test
US20130035292A1,COC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](NC(=O)OCc1ccccc1)[C@H](C)OC(C)=O.N>>C[C@H](O)[C@@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)ON,,CO,,,,test
US20060106075A1,CC(C)Oc1nc2c(OC(C)(C)C)ccc([C@@H](O)CN[C@H]3CCC[C@H]3OCc3ccccc3)c2s1>>O=c1[nH]c2c(O)ccc([C@@H](O)CN[C@H]3CCC[C@H]3OCc3ccccc3)c2s1,,CC(C)O,,Cl,,test
US20120270938A1,COCOc1c(C)cc(/C=C/c2cc(C(=O)O)cc(N(C)C)c2)cc1C.Oc1ccc(F)cc1>>COCOc1c(C)cc(/C=C/c2cc(C(=O)Oc3ccc(F)cc3)cc(N(C)C)c2)cc1C,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20160060260A1,CC(C)(C)OC(=O)N1CCC(CBr)CC1.Cn1c(=O)n(C)c2cc(Oc3cccc(O)c3)c(N)cc21>>Cn1c(=O)n(C)c2cc(Oc3cccc(OCC4CCN(C(=O)OC(C)(C)C)CC4)c3)c(N)cc21,,CN(C)C=O,,[I-].[K+],,test
US20150307476A1,CC(C)(C)OC(=O)NC1N=CC(Br)=CC1(O)Br.C[C@H](O)c1c(Cl)ccc(F)c1Cl>>CC(Oc1cc(Br)cnc1NC(=O)OC(C)(C)C)c1c(Cl)ccc(F)c1Cl,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090264404A1,COC(=O)c1cc(O)n(C)n1.ClCCCBr>>COC(=O)c1cc(OCCCCl)n(C)n1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20090143402A1,CCC(=O)C(C(=O)N[C@@H](CC)c1ccccc1)c1ccccc1C(=O)O.Nc1ccccc1>>CCc1c(C(=O)N[C@@H](CC)c2ccccc2)c2ccccc2c(=O)n1-c1ccccc1,,CC#N,,,,test
US20090253687A1,COc1ccc(O)c(C(=O)O)c1>>COc1ccc(O)c(CO)c1,,C1CCOC1,,,,test
US20080058304A1,CCC=CCCc1cc(C(=O)OC)cc(OC)c1OC>>CCCCCCc1cc(C(=O)OC)cc(OC)c1OC,,CCOC(C)=O,,,,test
US05262390,CC(C)N1CC(=O)N(c2ccc(O)cc2F)C1=O.COC(=O)C(C)Oc1cc(Cl)ccc1CCl>>COC(=O)C(C)Oc1cc(Cl)ccc1COc1ccc(N2C(=O)CN(C(C)C)C2=O)c(F)c1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070249670A1,CCCCBr.COC(=O)C1(NC(=O)c2cc3ccccc3cc2NC(=O)Nc2c(C)cc(C)cc2C)CCNCC1>>CCCCN1CCC(NC(=O)c2cc3ccccc3cc2NC(=O)Nc2c(C)cc(C)cc2C)(C(=O)OC)CC1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20060258659A1,CCCCCN1C(=O)C(O)(c2ccc3c(c2)OCO3)c2cccnc21.NCc1ccccc1>>CCCCCN1C(=O)C(NCc2ccccc2)(c2ccc3c(c2)OCO3)c2cccnc21,,ClCCl,O,CCN(C(C)C)C(C)C,O=S(Cl)Cl,test
US06518257B1,CC(C)C(O)(c1ccc(B(O)O)cc1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.CNC(=O)Cc1cccc(Br)c1>>CNC(=O)Cc1cccc(-c2ccc(C(O)(c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)C(C)C)cc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US09273028B2,CC(C)(C)OC(=O)N1CCCC(n2cnc3cnc(N=C(c4ccccc4)c4ccccc4)cc32)C1.Cl>>Cl.Nc1cc2c(cn1)ncn2C1CCCNC1,,C1CCOC1,,,,test
US20100137281A1,CCOC(=O)Nc1sc(CC)cc1C(=O)NCCO[Si](C)(C)C(C)(C)C>>CCc1cc2c(=O)n(CCO[Si](C)(C)C(C)(C)C)c(=O)[nH]c2s1,,CCOC(C)=O,,CN(C)C=O,,test
US20160052920A1,C[C@](N)(C[C@H](O)C(F)(F)F)c1nc(Cl)ccc1F.N#CBr>>C[C@@]1(c2nc(Cl)ccc2F)C[C@@H](C(F)(F)F)OC(N)=N1,,CCO,,O=C([O-])O.[Na+],,test
US20030166639A1,Cc1cncc(-c2cccc(C(=O)CC(=O)OC(C)(C)C)c2)n1.Nc1cc(Cl)c(Cl)cc1N>>Cc1cncc(-c2cccc(C3=Nc4cc(Cl)c(Cl)cc4NC(=O)C3)c2)n1,,Cc1ccccc1C,,,,test
US20020115684A1,Cc1ccncc1C(=O)O.O=C=O>>O=C(O)Cc1ccncc1C(=O)O,,C1CCOC1,,Cl,[Li]CCCC,test
US20140155398A1,O=C(O)c1c(Cl)cccc1Cl.O=[N+]([O-])O>>O=C(O)c1c(Cl)ccc([N+](=O)[O-])c1Cl,,O=S(=O)(O)O,,,,test
US20140088075A1,CCCN(C)C.CCn1c(=O)c(-c2cc(N)c(F)cc2Cl)cc2cnc(Cl)cc21.CN(C)C=O>>CCn1c(=O)c(-c2cc(N)c(F)cc2Cl)cc2cnc(NCCCN(C)C)cc21,,O,,,,test
US20130150343A1,Fc1ccc2nnc(Cl)n2c1.OCCN1CCNCC1>>OCCN1CCN(c2nnc3ccc(F)cn23)CC1,,CC(=O)N(C)C,,,,test
US20070123504A1,CCOC(=O)c1cc(C2CCCCC2)oc1C>>Cc1oc(C2CCCCC2)cc1C(=O)O,,CCO,O,Cl,[Na+].[OH-],test
US20040171881A1,CCCCI.COC(=O)c1cc(N(C)S(C)(=O)=O)c2cc[nH]c2c1>>CCCCn1ccc2c(N(C)S(C)(=O)=O)cc(C(=O)O)cc21,,CN(C)C=O,,[K+].[OH-],,test
US04243678,CCOC(=O)CCCCBr.Nc1ccc2c(c1)CCC2>>CCOC(=O)CCCCNc1ccc2c(c1)CCC2,,CCOCC,,CCN(C(C)C)C(C)C,,test
US04789704,C=CCc1ccccc1O.O=C(c1ccccc1)c1ccc(F)cc1>>CC=Cc1ccccc1Oc1ccc(C(=O)c2ccccc2)cc1,,Cc1ccccc1,,CN1CCCC1=O,O=C([O-])[O-].[K+].[K+],test
US20040176325A1,CC(C)(C)OC(=O)N1CCC(N)C1.CC(C)Cn1ncc2cc(Oc3ccc(F)cc3)c(C(N)=O)cc21>>CC(C)Cn1ncc2cc(Oc3ccc(F)cc3)c(C(=O)NC3CCN(C(=O)OC(C)(C)C)C3)cc21,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20090240052A1,CC(C)(C)OC(=O)c1ccc(CCc2ccccc2)cc1N.O=S(=O)(Cl)Cc1ccccc1>>CC(C)(C)OC(=O)c1ccc(CCc2ccccc2)cc1NS(=O)(=O)Cc1ccccc1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20100009991A1,COC(=O)CCc1cn(C(=O)OC(C)(C)C)c2ccccc12>>CC(C)(C)OC(=O)n1cc(CCCO)c2ccccc21,,O,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04000151,Cc1nnc(CBr)n1-c1ccc(Cl)cc1C(=O)c1c(F)cccc1F.N>>Cc1nnc2n1-c1ccc(Cl)cc1C(c1c(F)cccc1F)=NC2,,CO,,,,test
US20150011508A1,Cc1nc(-c2ccc(C)c(NC(=O)c3cnc4ccc(Br)cn34)c2)no1.Cc1nn(CCN2CCOCC2)c(C)c1B1OC(C)(C)C(C)(C)O1>>Cc1nc(-c2ccc(C)c(NC(=O)c3cnc4ccc(-c5c(C)nn(CCN6CCOCC6)c5C)cn34)c2)no1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20050026987A1,COC(=O)CN=[N+]=[N-].COCc1cccc(C=O)c1>>COCc1cccc(C=C(N=[N+]=[N-])C(=O)OC)c1,,CO,,C[O-].[Na+],,test
US20090137609A1,CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc(-c2ccc(CC(=O)OC)c(F)c2)c(C)c1>>CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc(-c2ccc(CC(=O)O)c(F)c2)c(C)c1,,CO,,[Na+].[OH-],[Cl-].[NH4+],test
US04558143,CC1(C)CC(=O)CC(=O)C1.O=CCCl>>CC1(C)CC(=O)c2ccoc2C1,,O,,O=C([O-])O.[Na+],,test
US06387911B1,COc1ccc(C#N)c(CN=[N+]=[N-])c1>>COc1ccc(C#N)c(CN)c1,[Pd],CCOC(C)=O,,,,test
US20090156603A1,Fc1ccc(C(F)(F)F)cc1Br.Nc1ncccc1O>>Nc1ncccc1Oc1ccc(C(F)(F)F)cc1Br,,CN(C)C=O,,[H-].[Na+],,test
US20040010009A1,C=O.CC(C)(C)OC(=O)N1CCC(Oc2ccc(NC/C=C/c3cccc(C#N)c3)cc2)CC1>>CN(C/C=C/c1cccc(C#N)c1)c1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1,,CO,ClCCl,CC(=O)O,[BH3-]C#N.[Na+],test
US20140235647A1,Cc1ccncc1-c1ccnc(C(=O)c2ccccc2)c1F.NO>>Cc1ccncc1-c1ccnc(/C(=N\O)c2ccccc2)c1F,,c1ccncc1,,Cl,,test
US20100022541A1,COC(=O)CN(Cc1ccccn1)C(=O)c1nc(-c2ccc(OC)cc2)oc1C>>Cc1oc(-c2ccc(O)cc2)nc1C(=O)N(CC(=O)O)Cc1ccccn1,,ClCCl,,BrB(Br)Br,,test
US20070191405A1,CC(C)(C)OC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(C2CCNCC2)cc1>>CC(C)(C)OC(=O)N1CCC(c2ccc(N)cc2)CC1,CN(C)c1ccncc1,ClCCl,,O=C([O-])O.[Na+],,test
US05516797,COc1ccc(C=CC(=O)O)cc1.O=C(OCc1ccccc1)[C@@H]1CCCCN1>>COc1ccc(C=CC(=O)N2CCCC[C@H]2C(=O)OCc2ccccc2)cc1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20060160872A1,O=C1CCc2cccc(O)c2C1>>Oc1cccc2c1CC(O)CC2,,CO,O,[BH4-].[Na+],,test
US20050143452A1,Cc1ccccc1-c1c(Cl)ccc2c1OC(CN=[N+]=[N-])C2>>Cc1ccccc1-c1c(Cl)ccc2c1OC(CN)C2,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04985444,Nc1ncc(-c2c(-c3ccccc3)nn3ccccc23)cn1.O=N[O-]>>O=c1ncc(-c2c(-c3ccccc3)nn3ccccc23)c[nH]1,,O,,O=S(=O)(O)O,,test
US05304653,COC(=O)CC=C(C=Cc1ccccc1)O[Si](C)(C)C.O=C1CCC(=O)N1Br>>COC(=O)CC(Br)C(=O)C=Cc1ccccc1,,C1CCOC1,,,,test
US05912244,CC(C)(C)[Si](C)(C)Cl.CC1=Cc2cc(Sc3cccc(O)c3)ccc2OC1(C)C>>CC1=Cc2cc(Sc3cccc(O[Si](C)(C)C(C)(C)C)c3)ccc2OC1(C)C,,CN(C)C=O,,O,c1c[nH]cn1,test
US20130252941A1,C=Cc1cc(Cl)c(-n2cc3c(Nc4cc(C)ncn4)ncc(F)c3n2)c(C#N)c1.O=[Os](=O)(=O)=O>>Cc1cc(Nc2ncc(F)c3nn(-c4c(Cl)cc(C=O)cc4C#N)cc23)ncn1,O=[Os](=O)(=O)=O,CC(C)=O,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20150197509A1,CCN(CC(=O)NCc1cc(-c2ccc(C(F)(F)F)cc2)ncn1)C(=O)OC(C)(C)C>>CCNCC(=O)NCc1cc(-c2ccc(C(F)(F)F)cc2)ncn1,,Cl,,C1COCCO1,,test
US20080004285A1,C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1c1nc(N)nc2ccc(-c3ccc(F)cc3)nc12.O=C(Cl)COc1ccc(Cl)cc1>>C[C@@H]1CN(C(=O)COc2ccc(Cl)cc2)CCN1c1nc(N)nc2ccc(-c3ccc(F)cc3)nc12,,CO,ClCCl,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20100190825A1,CCO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C)c(F)cc3N)CC2)CC1.ClCCl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCO[C@@H]1CC[C@@H](N2CCC(n3c(=O)[nH]c4cc(F)c(C)cc43)CC2)CC1.Cl,,ClCCl,O,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20080280906A1,CCN(C(=O)C(C)C)c1cnoc1C>>CCN(C(=O)C(C)C)/C(=C\N)C(C)=O,[Pd],CCOCC,,CCO,,test
US20060074084A1,CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc3[nH]c(C(=O)O)c(-c4cccnc4)c3c2)cc1.CN(C)CCN>>CN(C)CCNC(=O)c1[nH]c2ccc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)cc2c1-c1cccnc1,,CO,ClCCl,,,test
US20070010526A1,CCCN.O=C(O)Cc1ccc(S(=O)(=O)Cl)cc1>>CCCNS(=O)(=O)c1ccc(CC(=O)O)cc1,,CO,,,,test
US20070082880A1,CCOC(=O)CCc1cc2c(Nc3ccc4[nH]ccc4c3)c(C#N)cnc2s1>>N#Cc1cnc2sc(CCC(=O)O)cc2c1Nc1ccc2[nH]ccc2c1,,C1CCOC1,Cl,[Na+].[OH-],,test
US20080242653A1,C[C@H]1CCCN1C[C@H]1C[C@@H]1c1ccc(-n2ncccc2=O)cc1.O=C(O)[C@@H](O)[C@H](O)C(=O)O>>C[C@H]1CCCN1C[C@H]1C[C@@H]1c1ccc(-n2ncccc2=O)cc1.O=C(O)[C@@H](O)[C@H](O)C(=O)O,,CO,,,,test
US20140128390A1,COc1cccc([C@H](C)N=C=O)c1.C[C@@H]1CN(c2ncnc3cc(-c4ccc(F)cc4)sc23)CCN1>>COc1cccc([C@H](C)NC(=O)N2CCN(c3ncnc4cc(-c5ccc(F)cc5)sc34)C[C@H]2C)c1,,CC#N,,CCN(CC)CC,Cl,test
US20140315888A1,CN(C(=O)OC(C)(C)C)C1CNC1.Clc1cnc2nc(Cl)n3ncnc3c2c1>>CNC1CN(c2nc3ncc(Cl)cc3c3ncnn23)C1,,CN(C)C=O,,,,test
US20090099195A1,CC(=O)N1CCN(c2nc3c(c(N4CCC[C@@H]4c4ccc(O)c(F)c4)n2)CN(C(C)C)C3=O)CC1.CCI>>CCOc1ccc([C@H]2CCCN2c2nc(N3CCN(C(C)=O)CC3)nc3c2CN(C(C)C)C3=O)cc1F,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130184222A1,C[Si](C)(C)C#N.Cc1ccccc1C=O.Nc1cccc(F)c1>>Cc1ccccc1C(C#N)Nc1cccc(F)c1,,CCOCC,,,,test
US20080262042A1,CN(Cc1c[nH]c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C.O=S(=O)(Cl)c1ccccn1>>CN(Cc1cn(S(=O)(=O)c2ccccn2)c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C,,C1CCOC1,O,C1COCCOCCOCCOCCO1,[H-].[Na+],test
US20070179136A1,NC(=O)c1cc(F)cc2[nH]c(-c3ccc(C4CCCN(C(=O)OCc5ccccc5)C4)cc3F)nc12>>NC(=O)c1cc(F)cc2[nH]c(-c3ccc(C4CCCNC4)cc3F)nc12,,O=C(O)C(F)(F)F,,,,test
US20150266874A1,CCOC(=O)/C(=C\N(C)C)C(=O)c1nc2c(s1)CCCC2.NN>>CCOC(=O)c1c[nH]nc1-c1nc2c(s1)CCCC2,,CCO,CCOCC,O,,test
US20090275567A1,Cc1ncc(-c2ccnc(NC3CCNCC3)n2)n1C(C)C.O=S(=O)(Cl)CCCl>>C=CS(=O)(=O)N1CCC(Nc2nccc(-c3cnc(C)n3C(C)C)n2)CC1,,ClCCl,,,,test
US20090163472A1,CC(C)(C)OC(=O)N1CC[C@@H](N)[C@H](O)C1.O=Cc1ccccc1>>CC(C)(C)OC(=O)N1CC[C@@H](NCc2ccccc2)[C@H](O)C1,,CCO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20050049262A1,C[C@H](CCCCn1c(=O)c2[nH]c(CNC(=O)OC(C)(C)C)nc2n(C)c1=O)N(C)C>>C[C@H](CCCCn1c(=O)c2[nH]c(CN)nc2n(C)c1=O)N(C)C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090099250A1,C=CC1=C(c2ccc(OC)cc2)CCCc2cc(OC)ccc21>>C=CC1=C(c2ccc(O)cc2)CCCc2cc(O)ccc21,,ClCCl,,BrB(Br)Br,O,test
US20050228027A1,CC(Cc1ccc(Cl)nc1)CS(C)=O.[N-]=[N+]=[N-]>>CC(Cc1ccc(Cl)nc1)CS(C)(=N)=O,,ClC(Cl)Cl,,O=S(=O)(O)O,,test
US04728644,CCN.CSc1ncnc2nc(-c3ccncc3)[nH]c12>>CCNc1ncnc2nc(-c3ccncc3)[nH]c12,,O,,,,test
US20140112945A1,COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4ccc(C(N)=O)cc4)NC(=O)OC(C)(C)C)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)Cc4ccc(C(N)=O)cc4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20030013715A1,C[C@@H]1CC[C@@H](NC(=O)c2cnc3c(F)cc(F)cc3c2Cl)CC1.O=S(Cl)Cl>>C[C@H]1CC[C@H](N)CC1.Cl,,CCN(CC)CC,,,,test
US20060084645A1,O=C1OC(=O)c2ccccc21.OC1CCN(c2cc(-c3ccccc3)nc(-c3ccccc3)n2)CC1>>O=C(O)c1ccccc1C(=O)OC1CCN(c2cc(-c3ccccc3)nc(-c3ccccc3)n2)CC1,CN(C)c1ccncc1,ClCCCl,,,,test
US20070219198A1,C[C@@H](O)CNC[C@H](C)NC(=O)OC(C)(C)C.O=C(Cl)OCc1ccccc1>>C[C@@H](O)CN(C[C@H](C)NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20050165001A1,CNCc1c(N)cccc1Br.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CN1Cc2c(Br)cccc2NC1=O,,ClCCl,,CCN(CC)CC,,test
US04057543,CC(=O)O[C@H]1CC[C@@]2(C)[C@H](CC[C@H]3[C@@H]4CC=C(C(C)=O)[C@@]4(C)CC[C@@H]32)C1.NO>>CC(=O)O[C@H]1CC[C@@]2(C)[C@H](CC[C@H]3[C@@H]4CC=C(C(C)=NO)[C@@]4(C)CC[C@@H]32)C1,,CCO,O,Cl,c1ccncc1,test
US20090221586A1,COC(=O)c1ccc(OC)c(OCc2ccccc2)c1>>COc1ccc(C(=O)O)cc1OCc1ccccc1,,CC#N,O,Cl,[Na+].[OH-],test
US05317018,N.O=C(O)c1ncn2c1CN=C(c1ccccc1Br)c1cc(F)ccc1-2>>NC(=O)c1ncn2c1CN=C(c1ccccc1Br)c1cc(F)ccc1-2,,ClCCl,,ClP(Cl)(Cl)(Cl)Cl,,test
US20110306587A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1CC2(CNC2)C1>>CC(=O)N1CC2(C1)CN(C(=O)OC(C)(C)C)C2,,ClCCl,,[K+].[OH-],,test
US20050090494A1,CC(=O)Nc1ccccc1OC[C@@]1(C)CO1.NC1CCN(Cc2ccc(Cl)cc2)CC1>>CC(=O)Nc1ccccc1OC[C@](C)(O)CNC1CCN(Cc2ccc(Cl)cc2)CC1,,CCO,O,,,test
US20130210844A1,CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)O)c1F.Nc1cccc2c(Oc3ccc(C(F)(F)F)cc3)ccnc12>>CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)Nc2cccc3c(Oc4ccc(C(F)(F)F)cc4)ccnc23)c1F,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20080045506A1,CC#N.O=C(CBr)c1ccc(Br)cc1>>Cc1nc(-c2ccc(Br)cc2)co1,,CCOCC,,CN1CCCC1=O,,test
US20110136780A1,CC(C)[C@H](C(=O)O)N1Cc2c(Cl)cnc3[nH]cc(c23)C1=O.N#CC1CCNC1>>CC(C)[C@H](C(=O)N1CCC(C#N)C1)N1Cc2c(Cl)cnc3[nH]cc(c23)C1=O,,C1CCOC1,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20140350019A1,Cc1cc(-c2cccc(F)c2)cc(CNc2c(C)ccc(OCC(=O)OC(C)C)c2C)c1F>>Cc1cc(-c2cccc(F)c2)cc(CNc2c(C)ccc(OCC(=O)O)c2C)c1F,,C1CCOC1,,[Li+].[OH-],,test
US04232037,BrBr.COc1cccc(OC)c1C(=O)O>>COc1ccc(Br)c(OC)c1C(=O)O,,C1COCCO1,ClC(Cl)Cl,,,test
US20040023964A1,CC1(C)COB(B2OCC(C)(C)CO2)OC1.Fc1ccc(Br)cc1-c1ccccn1>>OB(O)c1ccc(F)c(-c2ccccn2)c1,,CS(C)=O,,C1COCCO1,CC(=O)[O-].[K+],test
US20140088078A1,O=C(N1CC(c2cccc(F)c2)C1)C(F)(F)F.O=S(=O)(O)Cl>>O=C(N1CC(c2cc(F)ccc2S(=O)(=O)Cl)C1)C(F)(F)F,,CCOC(C)=O,,,,test
US20130053365A1,Cn1ncnc1Cc1n[nH]c(=O)c2cc(F)cc(N/N=C/c3ccc(F)cc3)c12>>Cn1ncnc1C1c2n[nH]c(=O)c3cc(F)cc(c23)NNC1c1ccc(F)cc1,,C1CCOC1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04028356,NNC1=Nc2ccc(Cl)cc2C(c2ccccc2Cl)=NC1.O=C(CF)CCl>>FCC(CCl)=NNC1=Nc2ccc(Cl)cc2C(c2ccccc2Cl)=NC1,,C1CCOC1,,,,test
US06346527B1,CCOC(=O)C1=Cc2cccc(C(=O)O)c2OCC1>>CCOC(=O)C1=Cc2cccc(CO)c2OCC1,,C1CCOC1,,CC(C)COC(=O)Cl,CCN(CC)CC,test
US20060178510A1,COc1ccc(-c2nc(COc3ccc(C[C@@H]4CN(C(=O)OC(C)(C)C)CCO4)cc3Cl)no2)cc1>>COc1ccc(-c2nc(COc3ccc(C[C@@H]4CNCCO4)cc3Cl)no2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150087663A1,C[C@H](N)c1nc2cccc(Cl)c2c(=O)n1C1CC1.Cc1nnc(-c2c(N)ncnc2Cl)o1>>Cc1nnc(-c2c(N)ncnc2N[C@@H](C)c2nc3cccc(Cl)c3c(=O)n2C2CC2)o1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20020072521A1,COc1cc(C)cc(C)c1-c1nc(C)c(N)c(OC)n1.O=C(Cl)C1CC1>>C=C1NC(c2c(C)cc(C)cc2OC)=NC(OC)=C1NC(=O)C1CC1,,CCOC(C)=O,,CCN(CC)CC,O=C([O-])O.[Na+],test
US04857527,C=C1CC(=O)O1.NCCN1CCOCC1>>CC(=O)CC(=O)NCCN1CCOCC1,,CCOCC,,,,test
US20040254212A1,CC(C)(C)OC(=O)COC1CCC(c2cc3cccnc3c(-c3cccc(C#N)c3)n2)CC1>>N#Cc1cccc(-c2nc(C3CCC(OCC(=O)O)CC3)cc3cccnc23)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140171311A1,CC(C)(C)OC(=O)NCCNC(=O)c1ccc(/C=C/C(c2cc(Cl)c(Cl)c(Cl)c2)C(F)(F)F)cc1Br>>NCCNC(=O)c1ccc(/C=C/C(c2cc(Cl)c(Cl)c(Cl)c2)C(F)(F)F)cc1Br,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100048727A1,CCCCCCOc1ccc(CCCCC(=O)OCC)cc1>>CCCCCCOc1ccc(CCCCC(=O)O)cc1,,CO,,Cl,[Na+].[OH-],test
US20100261910A1,C#Cc1ccsc1.CC(=O)Nc1ccccc1OS(=O)(=O)c1ccc(C)cc1>>CC(=O)Nc1ccccc1C#Cc1ccsc1,,CCCCCCC,CCOC(C)=O,,,test
US20030207877A1,C=C(O[Si](C(C)C)(C(C)C)C(C)C)c1nccs1.O=C1CCC(=O)N1Cl>>CC(C)[Si](OC(=CCl)c1nccs1)(C(C)C)C(C)C,,C1CCOC1,,,,test
US20150152108A1,Clc1ccc2c(n1)N[C@H]1CCN2C1.FC(F)(F)C1CCCNC1>>FC(F)(F)C1CCCN(c2ccc3c(n2)N[C@H]2CCN3C2)C1,,COCCOC,O,CC(C)(C)[O-].[K+],,test
US20100292222A1,CCN1CCNCC1=O.FC(F)(F)c1nnc2ccc(N3CCC(c4ccc(OCCBr)cc4)CC3)nn12>>CCN1CCN(CCOc2ccc(C3CCN(c4ccc5nnc(C(F)(F)F)n5n4)CC3)cc2)CC1=O,,CN(C)C=O,ClCCl,CCOCC,,test
US20150284368A1,Cc1nc([C@@H]2C[C@H]2c2nc3ccccc3n2C)cc(-n2nc(C)nc2[C@H](C)O[Si](C)(C)C(C)(C)C)n1>>Cc1nc([C@@H]2C[C@H]2c2nc3ccccc3n2C)cc(-n2nc(C)nc2[C@H](C)O)n1,,C1CCOC1,,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20090156603A1,CC(C)(C)OC(=O)N1CCC(C(=O)CBr)CC1.O=C(NC(=S)Nc1ncc(Br)cc1Oc1ccc(F)cc1)c1ccccc1>>CC(C)(C)OC(=O)N1CCC(c2csc(Nc3ncc(Br)cc3Oc3ccc(F)cc3)n2)CC1,,CCO,,,,test
US20040132727A1,CC(O)c1ccc(F)cc1.COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2ncnc(Oc3ccc(NC(=O)OC(C)c4ccc(F)cc4)cc3)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20090191129A1,C#CCN(C)[C@H](C)[C@@H](O)c1ccccc1.CS(=O)(=O)Cl>>C#CCN(C)[C@H](C)[C@H](Cl)c1ccccc1,,C1CCOC1,,CCN(CC)CC,O=C([O-])[O-].[Na+].[Na+],test
US20070078156A1,O=[N+]([O-])c1ccc(Cl)c2cnsc12>>Nc1ccc(Cl)c2cnsc12,[Fe],CC(=O)O,,O,,test
US05627198,CC(C)(O)C(=O)O.Nc1nnc(C(=O)c2ccccc2)s1>>CC(C)(O)C(=O)Nc1nnc(C(=O)c2ccccc2)s1,,CC(=O)N(C)C,,O,O=S(Cl)Cl,test
US20070032478A1,CC(=O)c1ccc(C(=O)Nc2cccc(C(=O)c3ccc4c(c3)NC(=O)C4=CO)c2)s1.Cc1ccc(N)cc1O>>CC(=O)c1ccc(C(=O)Nc2cccc(C(=O)c3ccc4c(c3)NC(=O)C4=CNc3ccc(C)c(O)c3)c2)s1,,C1CCOC1,,,,test
US06613775B1,CCOC(=O)Cl.Cc1cccc(C)c1CNc1cccn2c(C)c(CO)nc12>>CCOC(=O)OCc1nc2c(NCc3c(C)cccc3C)cccn2c1C,,ClCCl,,O=C([O-])O.[Na+],,test
US20090156557A1,CCS(=O)(=O)c1cccc(-c2cc(C(=O)NC3CCN(C)CC3)c(C)c3[nH]c4ncc(C)cc4c23)c1.O=C(O)CC(O)(CC(=O)O)C(=O)O>>CCS(=O)(=O)c1cccc(-c2cc(C(=O)NC3CCN(C)CC3)c(C)c3[nH]c4ncc(C)cc4c23)c1.O=C(O)CC(O)(CC(=O)O)C(=O)O,,CC#N,O,,,test
US20140315881A1,COC(=O)Cc1ccc(O)c(C=O)c1.Cc1noc(C)c1C(=O)CBr>>COC(=O)Cc1ccc2oc(C(=O)c3c(C)noc3C)cc2c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120142717A1,CCOC(=O)/C(=C\O)CC.N=C(N)OCCc1cc(F)c(Oc2ccc(Cl)c(C(F)(F)F)c2)c(F)c1>>CCc1c[nH]c(OCCc2cc(F)c(Oc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)nc1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030176418A1,CCCC=C1CCNCC1.C[C@H](CI)CN1C(=O)CSc2ccccc21>>CCCC=C1CCN(C[C@@H](C)CN2C(=O)CSc3ccccc32)CC1,,CC#N,,,,test
US05013863,CCOP(=O)(CCC#N)c1ccccc1>>CCOP(=O)(CCCN)c1ccccc1,[Ni],CCO,,N,[H][H],test
US20080081817A1,CC(C)(C)OC(=O)N1CCN(c2ncnc3[nH]ncc23)CC1.CCOc1ccc(CO)cc1>>CCOc1cccc(Cn2ncc3c(N4CCN(C(=O)OC(C)(C)C)CC4)ncnc32)c1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140051679A1,O=C(Nc1ccc2c(c1)c(I)nn2C1CCCCO1)C(c1ccccn1)C1CCCC1>>O=C(Nc1ccc2[nH]nc(I)c2c1)C(c1ccccn1)C1CCCC1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20050070549A1,CC(C)(C)OC(=O)N1CC[C@@H](N2CC(=O)Nc3cc(Cl)ccc3C2)C1.CCI>>CCN1C(=O)CN([C@@H]2CCN(C(=O)OC(C)(C)C)C2)Cc2ccc(Cl)cc21,,C1CCOC1,,[H-].[Na+],,test
US04751295,CON=C(C(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(C=CCI)CS[C@H]12)c1nsc(N)n1.O=CNc1cccnc1>>CON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=C(C=CC[n+]3cccc(NC=O)c3)CS[C@H]12)c1nsc(N)n1,,CS(C)=O,,CCOC(C)=O,,test
US20090221645A1,C[Mg]Br.O=CC1=C(c2cccc3ccccc23)N2CCN=C2S1>>CC(O)C1=C(c2cccc3ccccc23)N2CCN=C2S1,,C1CCOC1,,,,test
US20070244159A1,CC(C)(C)C1Cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc2N1CCC#N.[N-]=[N+]=[N-].[NH4+]>>CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc2n1CCc1nn[nH]n1,,CN(C)C=O,,[Cl-].[Na+],,test
US04492700,Clc1nccnc1SN=Cc1ccccc1.O=C(OO)c1cccc(Cl)c1>>O=S(N=Cc1ccccc1)c1nccnc1Cl,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US04448784,COc1ccc2c(ccn2-c2cccc(C#N)c2)c1>>COc1ccc2c(c1)CCN2c1cccc(C#N)c1,,CC(=O)O,,[Na+].[OH-],,test
US05101059,C[Si](C)(C)C1(CO)c2ccccc2-c2ccccc21.O=C=Nc1ccccc1>>C[Si](C)(C)C1(COC(=O)Nc2ccccc2)c2ccccc2-c2ccccc21,,c1ccccc1,,,,test
US20140309244A1,C/C(=C\c1cccc(C2(C)OCCO2)n1)CO.CS(=O)(=O)Cl>>CC(=Cc1cccc(C2(C)OCCO2)n1)COS(C)(=O)=O,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20040044012A1,CN.CSc1ncc(C#N)c(Cl)n1>>CNc1nc(SC)ncc1C#N,,CCOCC,,,,test
US20140303164A1,CCN(C(=O)C(F)(F)F)c1nn(C)c2c(-c3ccc(C#CC(C)(C)O[Si](C)(C)C(C)(C)C)nc3[C@H](Cc3cc(F)cc(F)c3)NC(=O)OC(C)(C)C)ccc(Cl)c12>>CCNc1nn(C)c2c(-c3ccc(C#CC(C)(C)O[Si](C)(C)C(C)(C)C)nc3[C@H](Cc3cc(F)cc(F)c3)NC(=O)OC(C)(C)C)ccc(Cl)c12,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20160024009A1,CCI.COC(=O)[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)C(C)O>>CCN([C@H](C(=O)OC)C(C)O)S(=O)(=O)c1ccc(Cl)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20120329808A1,CC(C)(C)OC(=O)N1CCNCC1.CCC1SCc2ncnc(Cl)c21>>CCC1SCc2ncnc(N3CCN(C(=O)OC(C)(C)C)CC3)c21,,CCCCO,,,,test
US20030092694A1,O=C1OCCO1.Oc1ccccc1C(F)(F)F>>OCCOc1ccccc1C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130225553A1,CC(=O)C(C(=O)OC(C)(C)C)C(=O)c1ccc(Br)cc1[N+](=O)[O-]>>CC(=O)CC(=O)c1ccc(Br)cc1[N+](=O)[O-],,ClCCl,,O=C(O)C(F)(F)F,,test
US20060223745A1,C=CCBr.O=C(O)CCS>>C=CCSCCC(=O)O,,CO,,Cl,[Na+].[OH-],test
US06417203B1,CC(C)(C)OC(=O)N1CC[C@H](OS(C)(=O)=O)C1.[C-]#N>>CC(C)(C)OC(=O)N1CC[C@@H](C#N)C1,,CS(C)=O,,O,,test
US20080312234A1,CC(=O)OCCBr.Oc1ccc(Cl)nc1>>CCOC(=O)COc1ccc(Cl)nc1,,CC#N,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090306088A1,Cn1nnc2cc(C(=O)Cl)ccc21.NC1CCCn2c1nc(-c1ccncc1)cc2=O>>Cn1nnc2cc(C(=O)NC3CCCn4c3nc(-c3ccncc3)cc4=O)ccc21,,C1CCOC1,,CCN(CC)CC,O,test
US20090005519A1,C1CCOC1.C=CCN.CCCCCCn1ccc(N)nc1=O>>C=CCNC(=O)Nc1ccn(CCCCCC)c(=O)n1,,ClCCl,,c1c[nH]cn1,,test
US20140148459A1,O=C1OCCC1SCc1ccc(Br)cc1.OB(O)c1ccc(Cl)cc1>>O=C1OCCC1SCc1ccc(-c2ccc(Cl)cc2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20140179695A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1=NC2(CO1)c1cc(Br)ccc1OCC21COC1.CC1(C)OB(C2=CCOCC2)OC1(C)C>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1=NC2(CO1)c1cc(C3=CCOCC3)ccc1OCC21COC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20110166344A1,COC(=O)[C@@H]1[C@H]2C=C[C@@H]([C@@H]1NC(=O)OCc1ccccc1)[C@@H]1C[C@H]21>>COC(=O)[C@@H]1[C@H]2CC[C@H]([C@@H]3C[C@H]23)[C@@H]1N,[Pd],CCOC(C)=O,,,,test
US20060148858A1,CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCCO.COC(=O)Cc1ccc(OC)c(O)c1>>CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCCOc1cc(CC(=O)O)ccc1OC,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20140088101A1,COC(=O)c1nc(I)c2ccc(=O)n(Cc3ccccc3)c2c1O.N#C[Cu]>>COC(=O)c1nc(C#N)c2ccc(=O)n(Cc3ccccc3)c2c1O,,CN(C)C=O,,Cl,ClCCl,test
US06331549B1,CCOC(=O)C(C)C(C)=O.COc1ccccc1N>>COc1cccc2c(O)c(C)c(C)nc12,Cl,Cc1ccccc1,O,,,test
US20020086890A1,CC#CCOc1ccc(S(=O)(=O)C2(C(=O)OC)CCNCC2)cc1.CCOC(=O)Cl>>CC#CCOc1ccc(S(=O)(=O)C2(C(=O)OC)CCN(C(=O)OCC)CC2)cc1,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20150336894A1,BrP(Br)Br.COc1c[n+]([O-])ccc1[N+](=O)[O-]>>COc1cnccc1Br,,CCOC(C)=O,,[Na+].[OH-],,test
US20080171734A1,CS(=O)(=O)c1ccc(Br)cn1.Cc1cnc(NC(=O)c2cc(O)cc(O[C@H]3CCN(C)C3=O)c2)cn1>>Cc1cnc(NC(=O)c2cc(Oc3ccc(S(C)(=O)=O)nc3)cc(O[C@H]3CCN(C)C3=O)c2)cn1,,CC(=O)N(C)C,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05688795,Cl.ClCCNCCCl.Nc1ccccc1OC(F)F>>Cl.FC(F)Oc1ccccc1N1CCNCC1,,CCCCO,,O=C([O-])[O-].[K+].[K+],,test
US20140228386A1,O=C1N(c2cc(Cl)ncn2)CCN1c1cnccc1C1CC1.OB(O)C1CC1>>O=C1N(c2cc(C3CC3)ncn2)CCN1c1cnccc1C1CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1C,,O=C([O-])[O-].[K+].[K+],,test
US20060079685A1,Brc1ccc(C2CC2)cc1.C#CCOc1ccc([N+](=O)[O-])c(C=O)c1>>C#CCOc1ccc([N+](=O)[O-])c(C(O)c2ccc(C3CC3)cc2)c1,,C1CCOC1,,[Mg],[Cl-].[NH4+],test
US05817774,CN(C)C=O.COc1ccc(-c2cc(-c3ccccn3)nc(-c3cccc(Br)n3)c2)cc1>>COc1ccc(-c2cc(-c3ccccn3)nc(-c3cccc(C=O)n3)c2)cc1,,C1CCOC1,,[Li]CCCC,,test
US20160222030A1,CC(C)(C)OC(=O)NC1CCC/C1=C\c1cnc2ccccc2n1>>CC(C)(C)OC(=O)NC1CCCC1Cc1cnc2ccccc2n1,[Pd],CO,,[Na+].[OH-],,test
US04342587,COC(=O)c1ccccc1S(=O)(=O)N=C=O.Nc1ncc(Cl)cn1>>COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1ncc(Cl)cn1,,ClCCl,,,,test
US20070259886A1,COc1ccc(CN)cc1.O=C1OC(=O)c2c(O)cccc21>>COc1ccc(CN2C(=O)c3cccc(O)c3C2=O)cc1,,O,,CC(=O)O,,test
US20160115126A1,C=CC(=O)Cl.Cc1nc(C(N)=O)c2[nH]c(C)c(C)c2c1-c1cccc2c1CCNC2>>C=CC(=O)N1CCc2c(cccc2-c2c(C)nc(C(N)=O)c3[nH]c(C)c(C)c23)C1,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US06225288B1,COc1ccc(S(C)(=O)=O)cc1C.O=C1CCC(=O)N1Br>>COc1ccc(S(C)(=O)=O)cc1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US04847256,CN(C)C=CC(=O)c1cccc(Cl)c1.N#Cc1c[nH]nc1N>>N#Cc1cnn2c(-c3cccc(Cl)c3)ccnc12,,CC(=O)O,,,,test
US05489599,O=[N+]([O-])c1ccc(C2CCNCC2)cc1>>Nc1ccc(C2CCNCC2)cc1,[Ni],CCOC(C)=O,,[H][H],,test
US20030092740A1,CCO.COC(=O)c1cc(C(=O)O)nn1-c1ccc(OC)cc1>>CCOC(=O)c1cc(C(=O)OC)n(-c2ccc(OC)cc2)n1,,O=S(Cl)Cl,,CCN(C(C)C)C(C)C,,test
US05633379,COC(=O)CSCC(=O)Cl.COC(=O)c1ccc(Cl)cc1N>>COC(=O)CSCC(=O)Nc1cc(Cl)ccc1C(=O)OC,,ClCCl,,CCN(CC)CC,,test
US04496572,COC(=O)c1ccc2sc(CBr)cc2c1.c1c[nH]cn1>>COC(=O)c1ccc2sc(Cc3ncc[nH]3)cc2c1,,CC(C)=O,,O=C([O-])O.[Na+],,test
US20110166104A1,CC1(C)OB(c2cc(Oc3ccc(C#N)cc3F)ccc2C=O)OC1(C)C>>N#Cc1ccc(Oc2ccc3c(c2)B(O)OC3)c(F)c1,,CO,,Cl,[BH4-].[Na+],test
US20090299103A1,CC(C)O.COc1ccc(CC(=O)O)cc1>>COc1ccc(CC(=O)OC(C)C)cc1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150175604A1,N#Cc1cc2nc(Cl)ccc2n1S(=O)(=O)c1ccccc1>>N#Cc1cc2nc(Cl)ccc2[nH]1,,C1CCOC1,,[Na+].[OH-],,test
US20070167443A1,II.O=c1cc[nH]c2ccccc12>>O=c1c(I)c[nH]c2ccccc12,,CN(C)C=O,,[K+].[OH-],,test
US04888332,COC(=O)Cc1nc2nc(C)cc(S)n2n1>>Cc1cc(S)n2nc(CC(=O)O)nc2n1,,O,,Cl,[K+].[OH-],test
US03931195,O=[N+]([O-])c1ccccc1C=Cc1ccccn1>>Nc1ccccc1CCc1ccccn1,[Pd],CCO,,,,test
US04728662,COc1cccc(OC)c1Cl.O=C(Cl)c1cc(F)ccc1F>>COc1ccc(C(=O)c2cc(F)ccc2F)c(O)c1Cl,,ClCCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20100081653A1,CC(C)(C)C(=O)CC(=O)C(F)(F)F.N#CC(C(=N)N)=C1Nc2ccccc2S1>>CC(C)(C)c1cc(C(F)(F)F)nc(C(C#N)=C2Nc3ccccc3S2)n1,,CCOC(C)=O,CS(C)=O,C,C[O-].[Na+],test
US20140031364A1,COc1ccccc1N1CCNCC1.Cc1onc(-c2cccc(C(F)(F)F)c2)c1C(=O)O>>COc1ccccc1N1CCN(C(=O)c2c(-c3cccc(C(F)(F)F)c3)noc2C)CC1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20060084680A1,C=CCc1c(OCc2ccccc2)ccc2[nH]ccc12.CI>>C=CCc1c(OCc2ccccc2)ccc2c1ccn2C,O,CN(C)C=O,,[H-].[Na+],,test
US20140073799A1,CN1CC(=O)NC1=O.O=[N+]([O-])c1ccc(CBr)cc1>>CN1CC(=O)N(Cc2ccc([N+](=O)[O-])cc2)C1=O,,C1CCOC1,CN(C)C=O,O,[H-].[Na+],test
US06326369B1,CCOC(=O)CCCCCCCC1Cc2c(c(OC)c(OC)c(OC)c2OC)C1>>COc1c2c(c(OC)c(OC)c1OC)CC(CCCCCCCCO)C2,,CCOCC,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20020132812A1,Brc1cc2c(c(C(CC3=NCCN3)c3ccccn3)c1)OCC2.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2cc3c(c(C(CC4=NCCN4)c4ccccn4)c2)OCC3)cc1,,CCO,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],,test
US04219557,Nc1ccc(C(F)(F)F)cn1.O=C=NC(=O)c1c(Cl)cccc1Cl>>O=C(NC(=O)c1c(Cl)cccc1Cl)Nc1ccc(C(F)(F)F)cn1,,CCOC(C)=O,,,,test
US06034239,C=CCc1c(O)ccc2[nH]cc(CCNC(=O)CC)c12>>C=CCc1c(O)ccc2c1C(CCNC(=O)CC)CN2,,CC(=O)O,,O,[BH3-]C#N.[Na+],test
US04810708,O=c1c2c(n(-c3cccc(Cl)c3)c3ncccc13)CCS2>>O=c1c2cccnc2n(-c2cccc(Cl)c2)c2ccsc12,[Ni],CCO,,,,test
US20050059713A1,CCOC(C)=O.CI.O=C(O)c1cc(Br)cc(Cl)c1O>>COC(=O)c1cc(Br)cc(Cl)c1OC,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20090030218A1,CC(C)[Mg]Cl.Cc1cc(-c2ccc(C(=O)O)c(F)c2)cc(C)c1OCc1ccccc1>>Cc1cc(-c2ccc(C(=O)O)c(C(C)C)c2)cc(C)c1OCc1ccccc1,,C1CCOC1,,Cl,,test
US20090082379A1,C.CCOC(=O)CN(C)C.Nc1ccc(OC(F)(F)F)c([N+](=O)[O-])c1.O=C(Cl)OC(Cl)(Cl)Cl>>CC1(C)NC(=O)N(c2ccc(OC(F)(F)F)c([N+](=O)[O-])c2)C1=O,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US05721255,COc1ccc(S(C)(=O)=O)cc1CN[C@H]1C2CCN(CC2)[C@H]1C(c1ccccc1)c1ccccc1.CS(=O)(=O)O>>COc1ccc(S(C)(=O)=O)cc1CN[C@H]1C2CCN(CC2)[C@H]1C(c1ccccc1)c1ccccc1.CS(=O)(=O)O,,CC(C)=O,,,,test
US20120214794A1,Clc1ccc([Mg]Br)cc1.O=C1CCCc2sc(Br)cc21>>OC1(c2ccc(Cl)cc2)CCCc2sc(Br)cc21,,C1CCOC1,CCOC(C)=O,CCOCC,[Cl-].[NH4+],test
US20160158207A1,CC(=O)N1CCc2c(c(N3CC(CO[Si](C)(C)C(C)(C)C)Cc4cc(-c5cnn(C)c5)ccc43)nn2[C@H]2CCOC2)C1>>CC(=O)N1CCc2c(c(N3CC(CO)Cc4cc(-c5cnn(C)c5)ccc43)nn2C2CCOC2)C1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20120129870A1,CC(C)C(=O)Cl.N=C(NO)C(c1ccccc1)N1CCN(c2ccc([N+](=O)[O-])cc2F)CC1>>CC(C)c1nc(C(c2ccccc2)N2CCN(c3ccc([N+](=O)[O-])cc3F)CC2)no1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20030096826A1,CCOC(OCC)[C@H](CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccc([N+](=O)[O-])cc1OCc1ccccc1>>CCOC(OCC)[C@H](CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccc(N)cc1OCc1ccccc1,[Ni],C1CCOC1,,[H][H],,test
US20030127020A1,NC(=O)c1ccccc1O.OB(O)O.OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>NC(=O)c1ccccc1O.OB(O)O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO,,Cc1ccccc1,,,,test
US20100093718A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cc1nnc(Nc2cccc(Br)c2)s1>>Cc1nnc(Nc2cccc(B3OC(C)(C)C(C)(C)O3)c2)s1,,CS(C)=O,,CC(=O)[O-].[K+],,test
US20040092521A1,CON(C)C(=O)c1cccc(F)c1.C[C@@H]1CCCN1CCc1ccc2cc(Br)ccc2n1>>C[C@@H]1CCCN1CCc1ccc2cc(C(=O)c3cccc(F)c3)ccc2n1,,C1CCOC1,,[Li]CCCC,,test
US04517202,COC(=O)C1CCC2C(O)CCC12>>COC(=O)C1CCC2C(=O)CCC21,,CCOCC,ClCCl,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20120065231A1,CCCN(CC(=O)OCC)c1cc(Br)c(C#N)s1>>CCCN(CC(=O)O)c1cc(Br)c(C#N)s1,,O,,CO,[Na+].[OH-],test
US20110015196A1,C=C(C)[C@@H]1CC[C@]2(C(=O)N3CCC(CC)(C(=O)OCC)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CC1(C)CC(=O)OC1=O>>C=C(C)[C@@H]1CC[C@]2(C(=O)N3CCC(CC)(C(=O)OCC)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(=O)CC(C)(C)C(=O)O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,CCOC(C)=O,,c1ccncc1,,test
US20150299191A1,Nc1n[nH]c2ccccc12.O=C(O)c1ccco1>>O=C(Nc1n[nH]c2ccccc12)c1ccoc1,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US20040116438A1,CC(C)CC(=O)Cl.Nc1nccnc1C(=O)O>>CC(C)CC(=O)Nc1nccnc1C(=O)O,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20030166639A1,CCOc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3ccccn3)c2)cc1C(F)(F)F>>CCOc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3ccccn3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030166644A1,CN(C(=O)Cl)c1ccccc1.COc1ccc(-c2ccn(O)n2)cc1>>COc1ccc(-c2ccn(OC(=O)N(C)c3ccccc3)n2)cc1,,CCCCCCC,CCOC(C)=O,,,test
US04494980,COC(=O)Nc1nc(OC)cc(OC)n1.NS(=O)(=O)c1ccccc1-c1ccccn1>>COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ccccc2-c2ccccn2)n1,,Cc1ccccc1,ClCCl,C[Al](C)C,Cl,test
US20140275568A1,CCOC(OCC)OCC.Cl.NC(=O)C(N)C(N)=O.O>>Cl.NC(=O)c1nc[nH]c1O.O.O,,O,,CC(C)O,,test
US04939278,CCCC(=O)C1=C(O)CC2(CSCCSC2)OC1=O.CCON>>CCCC(=NOCC)C1=C(O)CC2(CSCCSC2)OC1=O,,CO,,Cl,,test
US20080039499A1,Nc1nc(C(=O)NC2CCN(Cc3ccccc3)CC2)cs1.O=C(Cl)c1ccc(F)c(Cl)c1>>O=C(Nc1nc(C(=O)NC2CCN(Cc3ccccc3)CC2)cs1)c1ccc(F)c(Cl)c1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20150183801A1,O=C(Nc1ccc(SC(F)(F)F)cc1)c1cnc(Cl)c(Br)c1.O[C@H]1CCNC1>>O=C(Nc1ccc(SC(F)(F)F)cc1)c1cnc(N2CC[C@H](O)C2)c(Br)c1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20160024104A1,C=Cc1c(C)cc2ncsc2c1-c1ccc(Cl)cc1.CC(C)(C)O.O>>Cc1cc2ncsc2c(-c2ccc(Cl)cc2)c1[C@H](O)CO,,O,,O=S([O-])[O-].[Na+].[Na+],,test
US20150018377A1,COc1cc(Oc2ccc(NC(=O)[C@@H](C)NC(=O)OC(C)(C)C)cn2)ccc1C>>COc1cc(Oc2ccc(NC(=O)[C@@H](C)N)cn2)ccc1C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140135318A1,CCCCN(CCCC)C(=O)c1cn(CCc2ccccc2)c(-c2ccc(C(=O)OC)cc2C(=O)O)n1.OC[C@@H]1Cc2ccccc2CN1>>CCCCN(CCCC)C(=O)c1cn(CCc2ccccc2)c(-c2ccc(C(=O)OC)cc2C(=O)N2Cc3ccccc3C[C@H]2CO)n1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130178459A1,COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc(CNC(=O)OC(C)(C)C)cc1.O=C1CCC(=O)N1Br>>COc1cc(Br)c2[nH]c(=O)c3sccc3c2c1-c1ccc(CNC(=O)OC(C)(C)C)cc1,,CN(C)C=O,,,,test
US05733912,c1ccc(COc2cncc(C34CCCN3CCC4)c2)cc1>>Oc1cncc(C23CCCN2CCC3)c1,[Pt],CO,,,,test
US20090131433A1,CC(C)(C)OC(=O)NC[C@@H]1C[C@H](O)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NC[C@@H]1C[C@H](OS(C)(=O)=O)C1,,ClCCl,,CCN(CC)CC,O,test
US06403610B1,C#CCN1CC[C@@H](CCC(O)c2ccnc3ccc(OC)cc23)[C@@H](C(=O)OC)C1.Fc1cccc(F)c1Br>>COC(=O)[C@H]1CN(CC#Cc2c(F)cccc2F)CC[C@H]1CCC(O)c1ccnc2ccc(OC)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCN(CC)CC,,CCOC(C)=O,O,test
US20130131018A1,CCC(CC)CBr.COc1cc(C=O)cc(OC)c1O>>CCC(CC)COc1c(OC)cc(C=O)cc1OC,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US03987047,CCCC(=O)Cl.Cc1c2c(nc3ccccc13)CCNCC2>>CCCC(=O)N1CCc2nc3ccccc3c(C)c2CC1,,c1ccncc1,,,,test
US05811428,CN(C)C=O.ClCCl.O=C(O)c1cc([N+](=O)[O-])cc(C(F)(F)F)c1>>CCOC(=O)c1cc(N)cc(C(F)(F)F)c1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US04053615,NC1CCN(C2CCCCC2)CC1.O=C1OC(=O)c2cc([N+](=O)[O-])ccc21>>O=C1c2ccc([N+](=O)[O-])cc2C(=O)N1C1CCN(C2CCCCC2)CC1,,ClC(Cl)Cl,,,,test
US03953397,O=C(Cl)c1c(Cl)cc(Cl)cc1Cl.O=C1NC(=O)C2C1CCC(Br)C2Br>>O=C(c1c(Cl)cc(Cl)cc1Cl)N1C(=O)C2CCC(Br)C(Br)C2C1=O,,c1ccccc1,,c1ccncc1,,test
US20140364393A1,CCOC(=O)c1csc(NC(=O)N2CCC(N3CCc4ccc(F)cc43)CC2)n1.CN>>CNC(=O)c1csc(NC(=O)N2CCC(N3CCc4ccc(F)cc43)CC2)n1,,CCO,,,,test
US04443243,C#CCBr.NS(=O)(=O)c1ccccc1O>>C#CCOc1ccccc1S(N)(=O)=O,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100137302A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.CN1CCCCC1CCCl>>CN1CCCCC1CCn1cc(B2OC(C)(C)C(C)(C)O2)cn1,,CCN(CC)CC,,Cl,,test
US20100152190A1,CO.COc1cc(C#N)ccc1C(=O)O>>COC(=O)c1ccc(C#N)cc1OC,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20090209607A1,CCn1nccc1-c1cc(C(=O)OC)sc1Cl.O=C1CCC(=O)N1Cl>>CCn1ncc(Cl)c1-c1cc(C(=O)OC)sc1Cl,,C1CCOC1,,,,test
US20130281433A1,OC(c1cccnc1)c1cc(Br)ccc1F>>O=C(c1cccnc1)c1cc(Br)ccc1F,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20100048561A1,CB1OB(C)OB(C)O1.CC(C)(C)OC(=O)N1CCC(Oc2ccc(Br)c3cnc(Nc4ccc(N5CCOCC5)c(Cl)c4)nc23)CC1>>Cc1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)c2nc(Nc3ccc(N4CCOCC4)c(Cl)c3)ncc12,,CN(C)C=O,,ClCCl,O=C([O-])[O-].[Na+].[Na+],test
US20090137561A1,COC(=O)c1cc(C2=CCCC2(C)C)c(OS(=O)(=O)C(F)(F)F)cc1F.COc1ccc(F)c(B(O)O)c1>>COC(=O)c1cc(C2=CCCC2(C)C)c(-c2cc(OC)ccc2F)cc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20160228450A1,C[C@@H](NC(=O)[C@H](Cc1ccc(-c2ncc(-c3ccc(O)cc3)cn2)cc1)NC(=O)c1ccc(C(C)(C)C)s1)C(=O)OC(C)(C)C.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>C[C@@H](NC(=O)[C@H](Cc1ccc(-c2ncc(-c3ccc(OS(=O)(=O)C(F)(F)F)cc3)cn2)cc1)NC(=O)c1ccc(C(C)(C)C)s1)C(=O)OC(C)(C)C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110021537A1,CCOC(=O)N1CCN(C(=O)[C@@H](N)CCC(=O)OC(C)(C)C)CC1.O=C(O)c1cc(O)n(-c2cccc(F)c2)n1>>CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(O)n(-c3cccc(F)c3)n2)CC1,,CCN(C(C)C)C(C)C,CN(C)C=O,ClCCCl,,test
US20020086887A1,CC(C)(C)OC(=O)NCCCC[C@H](CSc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc21.ClCCl>>CN(C)CCCC[C@H](CSc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc21,,O=C(O)C(F)(F)F,,,,test
US20040248854A1,COC(=O)CCCCCCN1C(=O)CCCC1/C=C/C(=O)Cc1ccccc1>>COC(=O)CCCCCCN1C(=O)CCCC1/C=C/C(O)Cc1ccccc1,,ClCCl,,CO,[BH4-].[Na+],test
US20110269744A1,CCOC(=O)N1CCc2cc(O)c(Br)cc2CC1.C[C@@H]1COSN1C(=O)OC(C)(C)C>>CCOC(=O)N1CCc2cc(Br)c(OC[C@@H](C)N)cc2CC1,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20100093694A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)OC)c(OS(=O)(=O)C(F)(F)F)cc3C)cc12.OB(O)c1ccccc1Cl>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)OC)c(-c4ccccc4Cl)cc3C)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,O,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US05234946,CS(=O)(=O)Cl.OCc1cccc(-n2cccc2)c1>>CS(=O)(=O)OCc1cccc(-n2cccc2)c1,,ClCCl,,CCN(CC)CC,,test
US20030013886A1,Cc1nc2cc(C)c(C)cc2[nH]1.O=Cc1ccccc1>>Cc1cc2nc(/C=C/c3ccccc3)[nH]c2cc1C,,CCOCC,,,,test
US05391771,C1CCOC1.CCO.CCOC(=O)CC(O)(CC(=O)OCC)C(=O)OCC>>OCC1CCOCC1.OCCC1CCOC1,,CCO,,[H][H],,test
US20080044380A1,CC(C)(C)OC(=O)N1CCC[C@H]1c1ncc(-c2cnc(Cl)nc2)[nH]1.C[Si](C)(C)CCOCCl>>CC(C)(C)OC(=O)N1CCC[C@H]1c1ncc(-c2cnc(Cl)nc2)n1COCC[Si](C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20120035214A1,COC[C@H](C)COCc1ccc([C@@]2(O)CCN(C(=O)OC(C)(C)C)C[C@@H]2c2ccc(-c3ccccc3CCNC(=O)OCc3ccccc3)cc2C)cc1>>COC[C@H](C)COCc1ccc([C@@]2(O)CCN(C(=O)OC(C)(C)C)C[C@@H]2c2ccc(-c3ccccc3CCN)cc2C)cc1,[Pd],CO,,,,test
US20080280926A1,Nc1ncnc2c1nc(Br)n2Cc1ccccc1.c1cn[nH]c1>>Nc1ncnc2c1nc(-n1cccn1)n2Cc1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US20080234281A1,CC(CO)Nc1ccc(F)c(Cl)c1.O=Cc1cccc(O)c1>>CC(CO)N(Cc1cccc(O)c1)c1ccc(F)c(Cl)c1,,ClCCCl,,[BH3-]C#N.[Na+],,test
US20090281160A1,COC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1.COP(C)(=O)OC>>COP(=O)(CC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1)OC,,C1CCOC1,,CC(=O)O,[Li]CCCC,test
US20080269208A1,COC(=O)[C@@H]1CCCN1CCNC(=O)OC(C)(C)C>>O=C1NCCN2CCC[C@@H]12,,CO,ClCCl,O=C(O)C(F)(F)F,,test
US20030013754A1,CCOC(=O)C(CC(=O)c1ccccc1)C(C)=O.Nc1cccc(F)c1>>CCOC(=O)c1cc(-c2ccccc2)n(-c2cccc(F)c2)c1C,,CCO,ClC(Cl)Cl,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100166699A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.CCOC(=O)COc1ccc(C2(c3ccc(Br)cc3)CCNCC2)cc1>>O=C(O)COc1ccc(C2(c3ccc(-c4cn[nH]c4)cc3)CCNCC2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20090182007A1,CC(C)(C)[Si](C)(C)OCCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.N#Cc1ccccc1CBr>>CC(C)(C)[Si](C)(C)OCCc1cncn1Cc1ccccc1C#N,,CC#N,,CCNCC,,test
US05204468,CC(=O)N1Cc2c(ccc(O)c2O)[C@H](c2ccc(O)c(O)c2)C1.CCO.Cl>>Cl.O.Oc1ccc([C@H]2CNCc3c2ccc(O)c3O)cc1O,,CCO,,,,test
US20150148308A1,CCSc1ccccc1-c1nc2cc(C(F)(F)F)cnc2[nH]1.O=C(OO)c1cccc(Cl)c1>>CCS(=O)(=O)c1ccccc1-c1nc2cc(C(F)(F)F)cnc2[nH]1,,ClC(Cl)Cl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20050032786A1,CC(C)(C)OC(=O)CCc1cccc(C#N)n1.Cc1ccc(C(=O)O)c(S)c1>>Cc1ccc2c(=O)nc(-c3cccc(CCC(=O)OC(C)(C)C)n3)sc2c1,,c1ccncc1,,,,test
US20120245144A1,CC(C)n1ncnc1-c1cn2c(n1)-c1cc(S(=O)(=O)N3CCNCC3)ccc1OCC2.CCCC(C)=O>>CCC(CC)N1CCN(S(=O)(=O)c2ccc3c(c2)-c2nc(-c4ncnn4C(C)C)cn2CCO3)CC1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130102776A1,O=C1CN(Cc2c(O)ccc3c2OCC3=O)CCN1.O=Cc1n[nH]c2ccccc12>>O=C1CN(Cc2c(O)ccc3c2O/C(=C\c2n[nH]c4ccccc24)C3=O)CCN1,,CO,,C1CCNCC1,,test
US20110070317A1,CCOP(=O)(N[C@@H]1CNCC[C@H]1OC)OCC.O=Cc1ccccc1>>CCOP(=O)(N[C@@H]1CN(Cc2ccccc2)CC[C@H]1OC)OCC,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20070010670A1,BrCCBr.CCN(CC)S(=O)(=O)c1ccc(O)c(NC(=O)c2cc(Cl)c(OCc3ccccc3)c(Cl)c2)c1>>CCN(CC)S(=O)(=O)c1ccc2c(c1)N(C(=O)c1cc(Cl)c(OCc3ccccc3)c(Cl)c1)CCO2,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04089960,CO.COC(=O)c1ccc(Cl)nc1Cl>>COC(=O)c1ccc(Cl)nc1OC,,CO,,[Na],C[O-].[Na+],test
US20140256706A1,CCc1cc(C)on1.O=C1CCC(=O)N1Br>>CCc1noc(C)c1Br,,CN(C)C=O,,CCOC(C)=O,,test
US05716624,CC1(C)CCSc2ccc(C=C(Br)Br)cc21>>C#Cc1ccc2c(c1)C(C)(C)CCS2,,O,,C1CCOC1,[Li]CCCC,test
US20050085470A1,CCC(=O)c1cc(Nc2ccc(F)c(Cl)c2)ccc1N.O=C(n1ccnc1)n1ccnc1.[Li]c1cccs1>>CCC1(c2cccs2)OC(=O)Nc2ccc(Nc3ccc(F)c(Cl)c3)cc21,,C1CCOC1,,,,test
US20120172333A1,CCOC(=O)c1c(NC(=O)CC#N)cc(Cl)n1-c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.N#Cc1cc(Br)cs1>>CCOC(=O)c1c(NC(=O)CC#N)cc(Cl)n1-c1ccc(-c2csc(C#N)c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20060173034A1,COc1cc2ncc(C(N)=O)c(Cl)c2cc1OC.COc1cccc(N)c1C>>COc1cc2ncc(C(N)=O)c(Nc3cccc(OC)c3C)c2cc1OC,,CN(C)C=O,O,CC(=O)O,O=C([O-])O.[Na+],test
US05296360,CC(=O)[O-].CCCCCCCCCCCCC/C=C/C(O)C(CNC(=O)CCCCCCCCCCCCCCCCC)O[C@@H]1O[C@H](CO)[C@@H](O[C@H]2O[C@@H](CO)[C@@H](O[C@H]3O[C@@H](CO)[C@@H](O)[C@@H](O[C@H]4O[C@@H](CO)[C@@H](O)[C@@H](O[C@@]5(C(=O)O)C[C@H](O)[C@@H](N)[C@H](C(O)C(O)O[C@@]6(C(=O)O)C[C@H](O)[C@@H](N)[C@H](C(O)C(O)CO)O6)O5)[C@@H]4O)[C@@H]3NC(C)=O)[C@@H](O[C@@]3(C(=O)O)C[C@H](O)[C@@H](N)[C@H](C(O)C(O)CO)O3)[C@@H]2O)[C@H](O)[C@H]1O>>CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O)[C@H]4O)[C@H]3NC(C)=O)[C@H](O[C@]3(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CO)O3)[C@H]2O)[C@H](O)[C@H]1O)NC(=O)CCCCCCCCCCCCCCCCC,,ClC(Cl)Cl,,O,,test
US04155913,CC(=O)Cl.NNC1=Nc2sccc2C(c2ccccc2Cl)=NC1>>Cc1nnc2n1-c1sccc1C(c1ccccc1Cl)=NC2,,ClCCl,,O=C([O-])O.[Na+],,test
US05610142,COC(OC)OC.NC(=O)C1(NCC2CCCCC2)CCN(Cc2ccccc2)CC1>>O=C1N=CN(CC2CCCCC2)C12CCN(Cc1ccccc1)CC2,,Cc1ccccc1,,CC(=O)O,,test
US20130210857A1,CC(C)c1nc2c(c(-c3ccc(F)cc3)c1C(OC(C)(C)C)C(=O)O)CNCC2(C)C.O=C(Cl)Cc1ccc(F)cc1>>CC(C)c1nc2c(c(-c3ccc(F)cc3)c1C(OC(C)(C)C)C(=O)O)CN(C(=O)Cc1ccc(F)cc1)CC2(C)C,,ClCCl,,CCN(CC)CC,,test
US20100022529A1,CCOC(=O)c1cc2c(cnn2C2CCCCO2)cc1O.O=[N+]([O-])c1ccc(F)c(F)c1>>CCOC(=O)c1cc2c(cnn2C2CCCCO2)cc1Oc1ccc([N+](=O)[O-])cc1F,,O,,CN(C)C=O,O=C([O-])O.[Na+],test
US20080171767A1,CCOC(=O)C(Oc1cc(C)c(C)c(C)c1)SC>>CSC(Oc1cc(C)c(C)c(C)c1)C(=O)O,,C1CCOC1,O,[Na+].[OH-],,test
US20050130985A1,C1CNCCN1.CC#CCn1c(Br)nc2c1c(=O)n(Cc1nc(C)c3ccccc3n1)c(=O)n2C>>CC#CCn1c(N2CCNCC2)nc2c1c(=O)n(Cc1nc(C)c3ccccc3n1)c(=O)n2C,,CN(C)C=O,,O,[Cl-].[Na+],test
US20090163488A1,Cc1cc(C(=O)Nc2cc(O)ccc2C)n(C)n1.O=[N+]([O-])c1ccc(Br)cn1>>Cc1cc(C(=O)Nc2cc(Oc3ccc([N+](=O)[O-])nc3)ccc2C)n(C)n1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US04119727,CCOC(=O)COc1cc(Cl)sc1C(=O)OCC>>O=C(O)COc1cc(Cl)sc1C(=O)O,,[Na+],[OH-],Cl,,test
US20150291625A1,CCN(CC)S(F)(F)F.Cc1ncnc(C)c1-c1ccc(Oc2nccc3occc23)cc1CO>>Cc1ncnc(C)c1-c1ccc(Oc2nccc3occc23)cc1CF,,ClCCl,,,,test
US20150361065A1,CC(C)(C)OC(=O)/C=C/c1ccc(Oc2c(-c3ccccc3C(F)F)sc3cc(O)ccc23)cc1>>O=C(O)/C=C/c1ccc(Oc2c(-c3ccccc3C(F)F)sc3cc(O)ccc23)cc1,,C1COCCO1,,Cl,,test
US04749790,CNC(=C[N+](=O)[O-])NCCSCc1ccc(CN(C)C)o1.N[C@@H](CC(=O)O)C(=O)O>>CNC(=C[N+](=O)[O-])NCCSCc1ccc(CN(C)C)o1.N[C@@H](CC(=O)[O-])C(=O)[O-],,ClCCl,,,,test
US20150291623A1,ClCI.O=C1C(c2ccc(Br)cc2O)c2ccccc2N1C(c1ccccc1)c1ccccc1>>O=C1N(C(c2ccccc2)c2ccccc2)c2ccccc2C12COc1cc(Br)ccc12,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060276433A1,O=C(NCCO)c1ccc([N+](=O)[O-])cc1.O=S(Cl)Cl>>O=C(NCCCl)c1ccc([N+](=O)[O-])cc1,,ClCCl,,O,,test
US20040048915A1,COC(=O)C(=O)c1c[nH]c2ccc(C)cc12.Cn1ccc2cccc(CC(N)=O)c21>>Cc1ccc2[nH]cc(C3=C(c4cccc5ccn(C)c45)C(=O)NC3=O)c2c1,,CN(C)C=O,,C1CCOC1,CC(C)(C)[O-].[K+],test
US20090069317A1,CCNC.COc1cccc2c1C(Cl)=NS2(=O)=O>>CCN(C)C1=NS(=O)(=O)c2cccc(OC)c21,,C1CCOC1,ClCCl,,,test
US04269788,CC(=O)CC1(c2ccccc2)C=CCC=C1.CCNCC.Cl>>CCN(CC)C(C)CC1(c2ccccc2)C=CCC=C1.Cl,,CO,,[BH3-]C#N.[Na+],,test
US20040224954A1,COc1cccc(C2(O)CCC(=O)CC2)c1>>COc1cccc(C2(O)CCC(O)CC2)c1,,CO,,O,[BH4-].[Na+],test
US20160159752A1,O=S(=O)(Cl)c1ccccc1.[N-]=[N+]=N[C@H](C(=O)Nc1cccc(F)c1CC[C@H](N)CO)[C@@H](c1ccc(F)cc1)C1CCOCC1>>[N-]=[N+]=N[C@H](C(=O)Nc1cccc(F)c1CCC1C[N@@]1S(=O)(=O)c1ccccc1)[C@@H](c1ccc(F)cc1)C1CCOCC1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20050176775A1,Cc1cc(OCc2ccccc2)c(Br)c(=O)[nH]1.O=C(O)Cc1ccc(CBr)cc1>>O=C(O)Cc1ccc(Cn2ccc(OCc3ccccc3)c(Br)c2=O)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04758668,CC(Cl)OC(=O)Cl.CN1CCC(c2nn(-c3ccc(C(F)(F)F)cc3)c3ccc(F)cc23)CC1>>Cl.c1cc(N2CCCCC2)c2cn[nH]c2c1,,ClCCCl,,,,test
US04806539,C=CCBr.O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O>>Br.C=CCN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US20110230462A1,CC(C)NC(=O)c1cccc(-c2cnc3c(n2)c(C(=O)N[C@H](C)C(=O)N2CC(C#N)C2)cn3COCC[Si](C)(C)C)c1>>CC(C)NC(=O)c1cccc(-c2cnc3[nH]cc(C(=O)N[C@H](C)C(=O)N4CC(C#N)C4)c3n2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100311965A1,Cc1c(F)ccc(C(=O)O)c1N.NC(N)=O>>Cc1c(F)ccc2c(=O)[nH]c(=O)[nH]c12,,O,,CN1CCCC1=O,,test
US06054413,C=CCOc1cc(Br)c(F)cc1Cl.O=C=O>>C=CCOc1cc(C(=O)O)c(F)cc1Cl,,C1CCOC1,,CC(C)[Mg]Cl,Cl,test
US20130338367A1,CCOC(=O)c1cn(-c2cccnc2)nc1C>>Cc1nn(-c2cccnc2)cc1C(=O)O,,CCO,,O,[K+].[OH-],test
US20120214802A1,CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)[C@H](Cc1ccccc1)N(Cc1ccccc1)Cc1ccccc1>>O=C1O[C@H]([C@H](Cc2ccccc2)N(Cc2ccccc2)Cc2ccccc2)[C@H]2CCCN12,,CO,,[BH4-].[Na+],,test
US20130116243A1,CCOC(=O)N1C(=O)c2ccccc2C1=O.COC1(OC)CC(N)(c2ccc(Br)cc2)C1>>COC1(OC)CC(c2ccc(Br)cc2)(N2C(=O)c3ccccc3C2=O)C1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20090246169A1,CCNC.COc1ccc2[nH]c3c(c2c1)CC1(C)C(=O)N(CCBr)C(=O)N1C3c1ccccc1>>CCN(C)CCN1C(=O)N2C(c3ccccc3)c3[nH]c4ccc(OC)cc4c3CC2(C)C1=O,,C1CCOC1,,,,test
US20030144175A1,O=C(N[C@@H](COCc1ccccc1)C(=O)NC1CCCN(S(=O)(=O)c2ccccn2)CC1=O)c1cc2ccccc2o1>>O=C(O)c1cc2ccccc2o1,[Pd],,,CCOC(C)=O,,test
US20100256126A1,CCOC(=O)C1(CC2CC2)CCN(C(=O)OC(C)(C)C)CC1.Cl>>CCOC(=O)C1(CC2CC2)CCNCC1.Cl,,C1COCCO1,,,,test
US20030195223A1,COc1ccc(O)cc1.O=[N+]([O-])c1ccccc1CBr>>COc1ccc(OCc2ccccc2[N+](=O)[O-])cc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20090306138A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(F)cc2)C1>>Fc1ccc(OC2CCNC2)cc1,,C1COCCO1,CCO,Cl,,test
US20130102620A1,CC(=O)Cl.Cc1cc(F)ccc1Nc1c(C(=O)N2CCC(c3ccccc3)CC2)cnc2c(S(N)(=O)=O)cnn12>>CC(=O)NS(=O)(=O)c1cnn2c(Nc3ccc(F)cc3C)c(C(=O)N3CCC(c4ccccc4)CC3)cnc12,CN(C)c1ccncc1,c1ccncc1,,Cl,,test
US04631286,N#Cc1ccc(Cl)cc1NC1=CC(=O)CCC1>>Nc1c2c(nc3cc(Cl)ccc13)CCCC2=O,,C1CCOC1,,Cl,O=C([O-])[O-].[K+].[K+],test
US20130184282A1,CCOC(=O)CCCCCCN1c2nc(-c3ccc(C)cc3)c(-c3ccc(C)cc3)nc2C(CNC(C)C)C1(c1ccc(C)cc1)c1ccc(C)cc1>>Cc1ccc(-c2nc3c(CNC(C)C)cn(CCCCCCC(=O)O)c3nc2-c2ccc(C)cc2)cc1,,CCO,CCOCC,[Na+].[OH-],,test
US20030078239A1,CCOC(=O)C(CCCCC(C)(C)CO)(CCCCC(C)(C)CO)C(=O)OCC>>CC(C)(CO)CCCCC(CCCCC(C)(C)CO)(C(=O)O)C(=O)O,,CCO,O,[K+].[OH-],,test
US20140343092A1,COC(=O)C(OC(C)(C)C)c1c(-c2ccc(Cl)cc2)c2ccn(Cc3ccccc3)c2c(=O)n1C.O=C1CCC(=O)N1Br>>COC(=O)C(OC(C)(C)C)c1c(-c2ccc(Cl)cc2)c2c(Br)cn(Cc3ccccc3)c2c(=O)n1C,,CN(C)C=O,,O,,test
US20080293768A1,CC(C)[Si](Cl)(C(C)C)C(C)C.Oc1ccc(I)nc1>>CC(C)[Si](Oc1ccc(I)nc1)(C(C)C)C(C)C,,CC#N,,c1c[nH]cn1,,test
US20060160856A1,COC(=O)c1ccc(N)c(C#N)c1>>N#Cc1cc(C(=O)O)ccc1N,,C1CCOC1,O,Cl,[Li+].[OH-],test
US06043242,CN(CCCO)c1ccnc(CO)c1Cl.O=S(Cl)Cl>>CN(CCCO)c1ccnc(CCl)c1Cl,,ClCCl,,,,test
US20050143427A1,CC(C)(C)OC(=O)N1[C@H](c2noc(=O)[nH]2)C[C@@H]2CCCC[C@@H]21>>O=c1[nH]c([C@@H]2C[C@@H]3CCCC[C@@H]3N2)no1,,ClCCl,,,,test
US20040157885A1,CCB(CC)c1cccnc1.COc1cc(I)ccc1C>>COc1cc(-c2cccnc2)ccc1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20150111867A1,CCCS(=O)(=O)NC1CN(c2ccc3c(c2)[C@H](Cc2ccccc2)[C@H](NC(=O)OCC)CO3)C1>>CCCS(=O)(=O)NC1CN(c2ccc3c(c2)[C@H](Cc2ccccc2)[C@H](N)CO3)C1,,[K+],[OH-],,,test
US20160159808A1,Cc1cn2ncc(C(=O)OC(C)(C)C)c2nc1Cl.[N-]=[N+]=[N-]>>Cc1cn2ncc(C(=O)OC(C)(C)C)c2nc1N=[N+]=[N-],,O,,CCO,,test
US20040009979A1,CC(C)(C)OO.CSc1ccc(S(=O)(=O)c2ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c(Cl)c2)cc1>>CS(=O)c1ccc(S(=O)(=O)c2ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c(Cl)c2)cc1,,Cc1ccccc1,ClC(Cl)Cl,,,test
US04774337,CCCSSCCC.Fc1ccccn1>>CCCSc1cccnc1F,,C1CCOC1,,O,CC(C)[N-]C(C)C.[Li+],test
US04349377,CSc1cc(O)ccc1Cl.FC(F)(F)c1ccc(Cl)c(Cl)c1>>CSc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Cl,,CS(C)=O,,[Na+].[OH-],,test
US20150329535A1,Nc1ccc(C=O)cc1.O=C(O)CCCc1ccc(-c2ccccc2)c(NC(=O)O[C@H]2CN3CCC2CC3)c1>>O=Cc1ccc(NC(=O)CCCc2ccc(-c3ccccc3)c(NC(=O)O[C@H]3CN4CCC3CC4)c2)cc1,,CN(C)C=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20010044435A1,OCCC1(CCO)CCN(Cc2ccccc2)CC1>>OCCC1(CCO)CCNCC1,[Pd],CCO,,,,test
US06583154B1,CC1CNCC(C)C1.Cc1nc(Cl)c2nc(-c3ccccc3)cc-2[nH]1>>Cc1nc(N2C[C@@H](C)C[C@H](C)C2)c2nc(-c3ccccc3)cc-2[nH]1,,O,,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20030050330A1,CO.COc1c(C)cc(C(=O)O)cc1C>>COC(=O)c1cc(C)c(OC)c(C)c1,,CO,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US05223498,CSC(=N)Nc1ccccc1N1CCOCC1.CSCCN>>CSCCNC(N)=Nc1ccccc1N1CCOCC1,,CCO,,I,,test
US20070010537A1,CCN(c1ccccc1)S(=O)(=O)c1cc(N)c(Cl)s1.COC(=O)c1ccccc1N=C=O>>CCN(c1ccccc1)S(=O)(=O)c1cc(-n2c(=O)[nH]c3ccccc3c2=O)c(Cl)s1,CN(C)c1ccncc1,C1CCOC1,,,,test
US05807851,CC1Cc2ccc(Br)cc2C(c2ccc([N+](=O)[O-])cc2)=NN1.CN=C=O>>CNC(=O)N1N=C(c2ccc([N+](=O)[O-])cc2)c2cc(Br)ccc2CC1C,,CCO,,,,test
US20060178400A1,CC(N)C#Cc1cnc(Oc2ccc(Oc3ccccc3)cc2)s1.CCC(=O)O>>CCC(=O)NC(C)C#Cc1cnc(Oc2ccc(Oc3ccccc3)cc2)s1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20040220411A1,CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(N)cc1.COC(=O)C(=O)[O-]>>COC(=O)C(=O)Nc1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20020169192A1,CCCCCCCN(CCc1cccc(O[Si](C)(C)C(C)(C)C)c1)C(=O)Nc1ccc(OC)cc1OC>>CCCCCCCN(CCc1cccc(O)c1)C(=O)Nc1ccc(OC)cc1OC,,O,,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US06664256B1,CSc1ccc(C(=O)C(CC(C)=O)c2ccc(Cl)cc2)cc1.NN>>CSc1ccc(-c2nnc(C)cc2-c2ccc(Cl)cc2)cc1,,CCO,,O,O,test
US20070004753A1,Cc1ccc(NC(C)(C)C#N)cc1.N#Cc1ccc(N=C=S)cc1C(F)(F)F.O>>Cc1ccc(N2C(=S)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C2(C)C)cc1,,CN(C)C=O,O,CO,Cl,test
US20090259049A1,CCCN(c1c(OC)nn2c(-c3c(Cl)cc(COC)cc3OC)csc12)C1CCOCC1.CS(=O)(=O)O>>CCCN(c1c(OC)nn2c(-c3c(Cl)cc(COC)cc3OC)csc12)C1CCOCC1.CS(=O)(=O)O,,CCOC(C)=O,,,,test
US20050113379A1,CCc1cc2c(nc1Br)c(C)cn2[C@H](C)CO[Si](C)(C)C(C)(C)C.COc1nc(C(C)C)ccc1B(O)O>>CCc1cc2c(nc1-c1ccc(C(C)C)nc1OC)c(C)cn2[C@H](C)CO[Si](C)(C)C(C)(C)C,,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20100249143A1,C=CC(C)=O.Nc1ccc2c(c1N)C(=O)c1ccccc1C2=O>>Cc1nc2ccc3c(c2nc1C)C(=O)c1ccccc1C3=O,,CN(C)C=O,,O=S(=O)(O)O,,test
US20040023995A1,CC(=O)O[C@H](C)CCCCn1c(=O)c2c(=O)cc(C)[nH]c2n(C)c1=O>>Cc1cc(=O)c2c(=O)n(CCCC[C@@H](C)O)c(=O)n(C)c2[nH]1,,CCOCC,,Cl,O=C([O-])O.[Na+],test
US20140155398A1,CCC(=O)Cl.Nc1cc(Cl)c(C(=O)n2ccc3cnccc32)c(Cl)c1>>CCC(=O)Nc1cc(Cl)c(C(=O)n2ccc3cnccc32)c(Cl)c1,,C1CCOC1,,CCN(CC)CC,,test
US20120202794A1,CCOC(=O)c1noc(-c2ccc(F)cc2)c1F>>O=C(O)c1noc(-c2ccc(F)cc2)c1F,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20020037910A1,CC(C)c1cccc(C(C)C)c1N.O=C(O)CCCCCCCCCCCCCCO>>CC(C)c1cccc(C(C)C)c1NC(=O)CCCCCCCCCCCCCCO,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20140371199A1,C1CNCCOC1.N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)O)cc4)cn23)cc1>>N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)N5CCOCC5)cc4)cn23)cc1,,CN(C)C=O,O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050009785A1,CC(O)CN.Cc1ccccc1C(=O)Cl>>Cc1ccccc1C(=O)NCC(C)O,,CCN(CC)CC,Cc1ccccc1,,,test
US20120129870A1,NCc1ccc(Cl)c(F)c1.O=C(Cl)C1CC1>>O=C(NCc1ccc(Cl)c(F)c1)C1CC1,,ClCCl,,CCN(CC)CC,,test
US20050176775A1,Cc1cc(O)cc(=O)o1.Cc1nn(C(=O)OC(C)(C)C)cc1N>>Cc1n[nH]cc1-n1c(C)cc(O)cc1=O,,OCC(F)(F)F,,,,test
US20100160355A1,CC(C)c1ccc2c(Nc3cc(N)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2n1.CC(C)c1ccc2c(Nc3cccc(C(=O)O)c3)ncnc2n1>>CC(C)c1ccc2c(Nc3cccc(C(=O)Nc4ccc(Sc5ccc(NC(=O)OC(C)(C)C)cc5)c(Nc5ncnc6nc(C(C)C)ccc56)c4)c3)ncnc2n1,,CS(C)=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070037809A1,O=[N+]([O-])c1ccc(-c2nc3ccncc3o2)cc1>>Nc1ccc(-c2nc3ccncc3o2)cc1,[Fe],CO,,O,[Cl-].[NH4+],test
US20030125370A1,Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1C(=O)On1nnc2cccnc21.NCC1CC1>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1C(=O)NCC1CC1,,CC(=O)N(C)C,,,,test
US20110269834A1,COC(=O)N[C@H](C)c1ccc2ccccc2c1>>CN[C@H](C)c1ccc2ccccc2c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040073025A1,CCOC(=O)C(O)c1ccccn1.Cl.[Na+]>>O=C(O)C(O)c1ccccn1.[Cl-].[Na+],,CCO,,O,,test
US20060074056A1,O=C(c1ccco1)c1cc2nccc(Cc3ccc([N+](=O)[O-])cc3F)c2s1>>Nc1ccc(Cc2ccnc3cc(C(=O)c4ccco4)sc23)c(F)c1,[Fe],CC(=O)O,,,,test
US20140045831A1,COc1ccc(CN(C(=O)OC(C)(C)C)c2ccc([N+](=O)[O-])c(C#N)n2)c(OC)c1>>COc1ccc(CN(C(=O)OC(C)(C)C)c2ccc(N)c(CN)n2)c(OC)c1,[Pd],C1CCOC1,CC(=O)O,,,test
US20150225397A1,CC1=C2CCC[C@H](O)[C@@]2(c2cccc(OCc3ccccc3)c2)CCC1=O>>C[C@@H]1C(=O)CC[C@@]2(c3cccc(O)c3)[C@H]1CCC[C@@H]2O,[Pd],c1ccncc1,,C1CCOC1,,test
US20100076026A1,O=S(Cl)Cl.[N-]=[N+]=Nc1cc(F)ccc1C(=O)Nc1ccc(Cl)cc1>>Fc1ccc2c(Cl)n(-c3ccc(Cl)cc3)nc2c1,,O=S(Cl)Cl,,ClCCl,,test
US20020111367A1,Nc1ccccc1Nc1ccccc1.O=C(O)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>O=C(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Nc1ccccc1Nc1ccccc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US05091432,CCN1CCCC1CN.CCOC(=O)CCn1cnc2c(=O)[nH]cnc21>>CCN1CCCC1CNC(=O)CCn1cnc2c(=O)[nH]cnc21,,CCOCC,,CC#N,,test
US06316482B1,COC(=O)c1cccc2[nH]c(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)nc12>>CC(C)(C)[Si](OCc1nc2c(C(=O)O)cccc2[nH]1)(c1ccccc1)c1ccccc1,,c1ccncc1,,[I-].[Li+],,test
US20060194816A1,Cc1c(C(=O)c2ccc(Cl)cc2Cl)oc2cc(Br)ccc12.Cc1cccc(B(O)O)c1>>Cc1cccc(-c2ccc3c(C)c(C(=O)c4ccc(Cl)cc4Cl)oc3c2)c1,,CCO,Cc1ccccc1,ClCCl,O=C([O-])[O-].[Na+].[Na+],test
US20160122331A1,COC(=O)c1cccc([C@H]2CC(=O)C[C@@H](c3ccccc3)O2)c1.CON>>CON=C1C[C@@H](c2ccccc2)O[C@@H](c2cccc(C(=O)OC)c2)C1,,CO,,Cl,CC(=O)[O-].[Na+],test
US20100113502A1,CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CNCC2.O=C(O)C(F)(F)F.O=C1CCC1>>CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCC1)CC2.O=C(O)C(F)(F)F,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130310357A1,COC(=O)c1ccc(CC2CCN(C(=O)OC(C)(C)C)CC2)cn1>>CC(C)(C)OC(=O)N1CCC(Cc2ccc(C(=O)O)nc2)CC1,,C1CCOC1,CO,[Na+].[OH-],,test
US20100227866A1,CC(C)(C)OC(=O)c1cc[nH]n1.O=C1c2ccccc2C(=O)N1CCBr>>CC(C)(C)OC(=O)c1ccn(CCN2C(=O)c3ccccc3C2=O)n1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070032531A1,Nc1nc(-c2ccc(Cl)cc2)cs1.O=C(O)/C=C/c1ccc2c(c1)OCO2>>O=C(C=Cc1ccc2c(c1)OCO2)Nc1nc(-c2ccc(Cl)cc2)cs1,,ClCCl,c1ccncc1,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20150011548A1,CC(=O)Nc1cc(N)cc(-c2ccc(F)cc2F)c1.O=[N+]([O-])c1cc(Br)ccc1F>>CC(=O)Nc1cc(Nc2ccc(Br)cc2[N+](=O)[O-])cc(-c2ccc(F)cc2F)c1,,CN(C)C=O,,[F-].[K+],,test
US20140249147A1,Nc1ccc2ncc(Br)n2n1.OB(O)c1ccccc1F>>Nc1ccc2ncc(-c3ccccc3F)n2n1,,CCO,O,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US20080176898A1,CCOC(=O)c1ccc(OCCCc2ccc(OCCCCOC3CCCCC3)cc2)c(CC(=O)NCCCC(=O)OC)c1>>O=C(O)CCCNC(=O)Cc1cc(C(=O)O)ccc1OCCCc1ccc(OCCCCOC2CCCCC2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20070066582A1,C[Mg]Br.N#Cc1ccc(Br)cn1>>CC(N)c1ccc(Br)cn1,,C1CCOC1,,CO,[BH4-].[Na+],test
US04304913,COc1cc(C(=O)Cl)cc(OC)c1OC.COc1cc2c(cc1OC)C1CC(N)CCN1CC2>>COc1cc2c(cc1OC)C1CC(NC(=O)c3cc(OC)c(OC)c(OC)c3)CCN1CC2.Cl,,c1ccncc1,,,,test
US04230710,CC(=O)Nc1ccc(N)cc1.O=C1CCN2CCc3ccccc3C2C1>>CC(=O)Nc1ccc(NC2CCN3CCc4ccccc4C3C2)cc1,,CN(C)C=O,O,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US06255496B1,CCCCCCCCCCCCSCCO.COC(=O)CCc1ccc(O)cc1>>CCCCCCCCCCCCSCCOc1ccc(CCC(=O)OC)cc1,,CCOC(C)=O,c1ccccc1,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100016352A1,COc1ccc(-c2oc3c(CC=C(C)C)c(O)cc(O)c3c(=O)c2OC)cc1OC.O=S(=O)(O)O>>COc1ccc(-c2oc3c(CCC(C)(C)O)c(O)cc(O)c3c(=O)c2OC)cc1OC,,CC(C)=O,,,,test
US20060189600A1,BrBr.O=C1NC(=O)C2(Cc3ccccc3C2)N1>>O=C1NC(=O)C2(Cc3ccc(Br)cc3C2)N1,,Br,,O,,test
US20070232583A1,CC(C)(C)NS(=O)(=O)c1cccc(-c2cccc(-c3nc(-c4ccc(Cl)c(Cl)c4)cc(C(F)(F)F)n3)c2)c1>>NS(=O)(=O)c1cccc(-c2cccc(-c3nc(-c4ccc(Cl)c(Cl)c4)cc(C(F)(F)F)n3)c2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040063735A1,COC(=O)C(CN1Cc2cn[nH]c2C(C)(C)C1)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>COC(=O)C(N)CN1Cc2cn[nH]c2C(C)(C)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090318714A1,COCCCOc1cc(-c2oc(=O)c(NC(C)=O)cc2C(C)C)ccc1OC>>COCCCOc1cc(-c2oc(=O)c(N)cc2C(C)C)ccc1OC,,CC(=O)O,,Cl,,test
US20130035325A1,C1CCC2=NCCCN2CC1.CC(C)NC(=O)CC#N.O=Cc1ccc2cn[nH]c2c1>>N#CC(=Cc1ccc2cn[nH]c2c1)C(=O)N1CCCC1,,C1CCOC1,,,,test
US20130252934A1,CC(C)(C)[Si](C)(C)Cl.CC(O)CC(O)c1ccc(Cl)c(F)c1>>CC(CC(O)c1ccc(Cl)c(F)c1)O[Si](C)(C)C(C)(C)C,,ClCCl,,c1c[nH]cn1,,test
US06133014,CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O.O=C(O)/C=C\C(=O)O>>O=C(O)/C=C/C(=O)O.O=C(O)/C=C\C(=O)O,[Pt],,,,,test
US20070135430A1,CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1.C[C@@H](Cn1ncc2ccc3oc(CN)cc3c21)NC(=O)OCc1ccccc1>>CC(=O)Nc1ccc(S(=O)(=O)NCc2cc3c(ccc4cnn(C[C@H](C)NC(=O)OCc5ccccc5)c43)o2)cc1,,C1CCOC1,O,CCN(CC)CC,O=C([O-])O.[Na+],test
US20090054440A1,Cc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)n(C(C)(C)C)n1>>Cc1cc(C2CCNCC2)n(C(C)(C)C)n1,,CO,,Cl,,test
US20040220225A1,CCN(CC)CC.Cc1cc(Cl)c2ccccc2n1.NCCCCCCO>>Cc1cc(NCCCCCCN2CCCCC2)c2ccccc2n1,,CCN(CC)CC,,[I-].[K+],,test
US20090011994A1,COC(CNC(=O)C(=O)Nc1ccc(OCC(C)(C)O)c(C)c1)OC>>Cc1cc(-n2ccnc(O)c2=O)ccc1OCC(C)(C)O,,CC(=O)O,,O=C(O)C(F)(F)F,,test
US20070049618A1,COc1ccc(C(=O)Cl)cc1.NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O>>COc1ccc(C(=O)NCc2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)cc1,,C1CCOC1,,CCN(CC)CC,Cl,test
US20140065136A1,OCC(Oc1c(Cl)nc(Cl)nc1N1CCOCC1)C1CC1>>Clc1nc2c(c(N3CCOCC3)n1)OC(C1CC1)CO2,,C1CCOC1,,[H-].[Na+],,test
US04367238,CCCC(C#N)(C(=O)OCC)c1cccc(Oc2ccccc2Cl)c1OC>>CCCC(C(=O)O)c1cccc(Oc2ccccc2Cl)c1OC,,CCO,O,[K+].[OH-],,test
US03932410,C#CC(C)(C)N1CCC(O)N(c2nnc(C(F)(F)F)s2)C1=O.CO>>C#CC(C)(C)N1CCC(OC)N(c2nnc(C(F)(F)F)s2)C1=O,,CO,,Cc1ccccc1S(=O)(=O)O,,test
US20080125398A1,O=P(OCCOS(=O)(=O)c1ccc(Br)cc1)(N(CCCl)CCCl)N(CCCl)CCCl.OCCS>>O=P(OCCSCCO)(N(CCCl)CCCl)N(CCCl)CCCl,,CO,,[Na+].[OH-],,test
US20070167452A1,COCOc1ccc(C(=O)NC[C@@H]2CC[C@@H](O)CC2)cc1.COc1ccc(O)cc1>>COCOc1ccc(C(=O)NC[C@@H]2CC[C@H](Oc3ccc(OC)cc3)CC2)cc1,,c1ccccc1,,CCCCP(=CC#N)(CCCC)CCCC,,test
US20040044012A1,CN1CCN(c2ccc(Nc3ncc4c(n3)N(C3CC5CCC3C5)C(=O)NC4)cc2)CC1>>CN1CCN(c2ccc(Nc3ncc4cnc(=O)n(C5CC6CCC5C6)c4n3)cc2)CC1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US04698348,CO.COc1ccc(-n2cnc3c(Cl)nc4ccccc4c32)cc1>>COc1ccc(-n2cnc3c(OC)nc4ccccc4c32)cc1,,CO,O,C[O-].[Na+],,test
US20060202179A1,COc1ccc(Br)cc1.O=C1Nc2ccccc2C1=O>>COc1ccc(N2C(=O)C(=O)c3ccccc32)cc1,I[Cu]I,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20110184017A1,CN[C@H]1CCN(S(=O)(=O)c2cccc3cncc(Cl)c23)C1.Cl>>CN[C@H]1CCN(S(=O)(=O)c2cccc3cncc(Cl)c23)C1.Cl,,CCO,,,,test
US20150038438A1,CN1CCCC(=O)c2ccc(Cl)cc21.COc1ccc(CN)c(OC)c1>>COc1ccc(CN=C2CCCN(C)c3cc(Cl)ccc32)c(OC)c1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,CCN(CC)CC,,test
US20120289522A1,Cc1noc(-c2ccc(Br)cc2)c1N.O=C=NCc1ccccc1>>Cc1noc(-c2ccc(Br)cc2)c1NC(=O)NCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20120308588A1,CCOC(=O)[C@H](O)[C@H](N)Cc1ccccc1Cl.O=C(O)CCCc1ccccc1C(=O)O>>CCOC(=O)[C@H](O)[C@@H](Cc1ccccc1Cl)NC(=O)CCCc1ccccc1C(=O)O,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20010056094A1,COC(=O)CC(=O)OC.COC(=O)c1cccc([N+](=O)[O-])c1Cl>>COC(=O)c1cccc([N+](=O)[O-])c1C(C(=O)OC)C(=O)OC,,CS(C)=O,,[H-].[Na+],,test
US20060205980A1,CC(C)(c1c(F)cc(O)cc1F)C(F)(F)F.CCOC(=O)CBr>>CCOC(=O)COc1cc(F)c(C(C)(C)C(F)(F)F)c(F)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06143774,CCCc1nc(SC2CCC(=CC(=O)OCC)CC2)c(C(=O)OCC)n1Cc1cc2c(cc1Cl)OCO2>>CCCc1nc(SC2CCC(=CC(=O)O)CC2)c(C(=O)O)n1Cc1cc2c(cc1Cl)OCO2,,CCO,,C1CCOC1,,test
US05098462,C=[N+]=[N-].CCOC(=O)c1ccc(=O)[nH]c1C(C)=O>>CCOC(=O)c1ccc(OC)nc1C(C)=O,,CCOCC,,,,test
US04605674,CC(=O)Nc1ccc(C=O)cc1.COc1cc(O)c(C(C)=O)c(OC)c1>>COc1cc(O)c(C(=O)C=Cc2ccc(N)cc2)c(OC)c1,,CCO,,O,[K+].[OH-],test
US20160207883A1,O=C1CCSCC1.OCCO>>C1COC2(CCSCC2)O1,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,,,test
US20160237268A1,CC(C)C[Al](CC(C)C)CC(C)C.CCCCCCC>>C=CC.CC(C)C[Al](CC(C)C)CC(C)C,,CCCCCCC,,,,test
US20030216417A1,COc1cc2c(Oc3ccc(Cl)cc3F)ncnc2cc1OCC1CCCN(C)C1>>COc1cc2c(=O)[nH]cnc2cc1OCC1CCCN(C)C1,,Cl,,,,test
US20060223872A1,Cc1cc(CNC(=O)Nc2ccc(C(F)(F)F)cc2)ccc1[N+](=O)[O-].O=C(Cl)C(=O)Cl>>Cc1cc(CN2C(=O)C(=O)N(c3ccc(C(F)(F)F)cc3)C2=O)ccc1[N+](=O)[O-],,ClCCl,,,,test
US04022905,CC(=O)Nn1cnnc1N(N=Cc1c(Cl)cccc1Cl)C(C)=O.COS(=O)(=O)OC>>CC(=O)N(N=Cc1c(Cl)cccc1Cl)c1nncn1N(C)C(C)=O,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US04254131,C1CCN(CC2CCNCC2)CC1.C=O.N#CCC(=O)O>>C=C(C#N)CN1CCC(CN2CCCCC2)CC1,,C1COCCO1,CCOCC,O=C=O,,test
US20070213348A1,COc1ccc(C(=C2CCCCCC2)c2ccc(C#N)cc2)cc1>>N#Cc1ccc(C(=C2CCCCCC2)c2ccc(O)cc2)cc1,,ClCCl,,BrB(Br)Br,O,test
US20150157611A1,CCOC(=O)c1cn2cc(Br)ccc2n1.NCc1ccc(OC(F)(F)F)cc1>>O=C(NCc1ccc(OC(F)(F)F)cc1)c1cn2cc(Br)ccc2n1,,ClCCl,,C[Al](C)C,,test
US05919782,CCOC(=O)N1CCC(OS(C)(=O)=O)CC1.O=Cc1ccc(O)cc1>>CCOC(=O)N1CCC(Oc2ccc(C=O)cc2)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110319378A1,BrCC1CC1.C=CC[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)CO)C1=O>>C=CC[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CC)COCC2CC2)C1=O,,CN(C)C=O,,[H-].[Na+],,test
US20160272617A1,Cc1cc(C(=O)NC(C)C)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2cc(Cl)c3oc(=O)[nH]c3c2)cc1.Cl>>Cc1cc(C(=O)NC(C)C)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2cc(Cl)c3oc(=O)[nH]c3c2)cc1.Cl,,C1COCCO1,CO,,,test
US20070078121A1,O=[N+]([O-])c1ccc2nc(O)ccc2c1>>Nc1ccc2[nH]c(=O)ccc2c1,O=[Pt]=O,CCO,,,,test
US20050203167A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCCc1ccc(CCO)cc1>>Cc1ccc(S(=O)(=O)O)cc1,,C1CCOC1,,C1CN2CCN1CC2,,test
US20060189682A1,CC[C@]1(C)OC(=O)C(OC(C)C)=C1c1ccc(S(C)(=O)=O)cc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC[C@]1(C)OC(=S)C(OC(C)C)=C1c1ccc(S(C)(=O)=O)cc1,,Cc1ccccc1,,,,test
US05273986,CC(C)C(=O)CBr.NC(=S)/C=C/c1cc([N+](=O)[O-])ccc1Cl>>CC(C)c1csc(/C=C/c2cc([N+](=O)[O-])ccc2Cl)n1,,CCO,,,,test
US20100305131A1,COC(=O)C(CC(=O)OC(C)(C)C)=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(-c2ccccc2)cc1>>COC(=O)/C(=C\c1ccc(-c2ccccc2)cc1)CC(=O)OC(C)(C)C,,Cc1ccccc1,,,,test
US20100144707A1,COCCOc1cc2c(=O)[nH]c(-c3cccc(OCc4ccccc4)c3)nc2cc1OC.O=C(Cl)C(=O)Cl>>COCCOc1cc2c(Cl)nc(-c3cccc(OCc4ccccc4)c3)nc2cc1OC,CN(C)C=O,ClCCl,,,,test
US20130190318A1,CN(C)S(=O)(=O)n1ccc(C(C)(NS(=O)C(C)(C)C)c2cccc(Cl)c2)n1>>CC(N)(c1cccc(Cl)c1)c1cc[nH]n1,,CO,,C1COCCO1,Cl,test
US20100105714A1,C#CC1(O)CCC(C2OCCO2)CC1.C[Si](C)(C)Cl>>C#CC1(O[Si](C)(C)C)CCC(C2OCCO2)CC1,CN(C)c1ccncc1,ClCCl,,O,,test
US20080153812A1,CC(C)N1CCCN(C(=O)OCc2ccccc2)CC1>>CC(C)N1CCCNCC1,[Pd],CCO,,,,test
US20130053407A1,CCOC(=O)c1c(N)cc(Cl)n1-c1ccc(-c2cccc(OC)c2O)cc1.O=C=Nc1ccccc1>>CCOC(=O)c1c(NC(=O)Nc2ccccc2)cc(Cl)n1-c1ccc(-c2cccc(OC)c2O)cc1,,Cc1ccccc1C,,,,test
US04282246,O=C(O)c1coc(Br)c1.Sc1cccc2ccccc12>>O=C(O)c1coc(Sc2cccc3ccccc23)c1,,O,,CN(C)C=O,,test
US07612075B2,CC(C)(C)OC(=O)N1CCNC(=O)C1.Clc1ncnc2cc(CBr)ccc12>>CC(C)(C)OC(=O)N1CCN(Cc2ccc3c(Cl)ncnc3c2)C(=O)C1,,C1CCOC1,CN(C)C=O,[H-].[Na+],[Cl-].[NH4+],test
US20160244437A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2cccc(-c3ccccc3S(=O)(=O)N3CCOCC3)c2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)CC1.Cl>>Cl.NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2cccc(-c3ccccc3S(=O)(=O)N3CCOCC3)c2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)CC1,,C1COCCO1,,CC#N,,test
US20160016948A1,CC[C@H](C)N.O=[N+]([O-])c1cnc(Br)cc1Br>>CC[C@H](C)Nc1cc(Br)ncc1[N+](=O)[O-],,C1CCOC1,O,CCN(CC)CC,,test
US20080312226A1,N#C[S-].O=C(CBr)c1ccc(Cl)cc1Cl>>N#CSCC(=O)c1ccc(Cl)cc1Cl,,CCO,,O,,test
US20090258874A1,COc1cc(Cl)c(C=O)cc1O.ClCCN1CCOCC1>>COc1cc(Cl)c(C=O)cc1OCCN1CCOCC1,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US20050124816A1,N#CSCCC(F)=C(F)F.S>>NC(=S)SCCC(F)=C(F)F,,COC(C)(C)C,,CCN(CC)CC,,test
US20110245224A1,C[C@H]1CNC[C@@H](C)O1.O=C(O)c1ncc(F)cc1F>>C[C@H]1CN(c2cc(F)cnc2C(=O)O)C[C@@H](C)O1,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20160184310A1,NC(=O)c1cc(F)cc(F)c1N.O=C1CCCC(=O)O1>>O=C(O)CCCc1nc2c(F)cc(F)cc2c(=O)[nH]1,,Cc1ccccc1,,,,test
US04281120,CC(C)N(c1nnc(N)s1)C(C)C.CCOC(=O)C#CC(=O)OCC>>CCOC(=O)c1cc(=O)nc2sc(N(C(C)C)C(C)C)nn12,,CCO,,,,test
US20140235660A1,COC(=O)/C=C/c1ccc(Oc2c(-c3ccc(OC)cc3)sc3cc(OC)ccc23)cn1>>COC(=O)/C=C/c1ccc(Oc2c(-c3ccc(O)cc3)sc3cc(O)ccc23)cn1,,ClCCl,,BrB(Br)Br,,test
US20090082378A1,CN.Clc1cccc(Cl)c1CBr>>CNCc1c(Cl)cccc1Cl,,CCO,,,,test
US04046773,Cc1ncc[nH]1.O=C=NC1CCCCC1>>Cc1nccn1C(=O)NC1CCCCC1,CCN(CC)CC,CCN(CC)CC,,O,,test
US20150266825A1,O=[N+]([O-])c1cc(CN2CCCC2)ccc1Cl>>Nc1cc(CN2CCCC2)ccc1Cl,,CCO,,Cl[Sn]Cl,,test
US06262099B1,COC(=O)C1(C)CC1(Br)Br>>CC1(C(=O)O)CC1(Br)Br,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20110263598A1,COc1ccc2c(c1)[C@]1(C[C@H]1c1ccc3c(-c4ccc(N5CCN(C)CC5)nc4)n[nH]c3c1)C(=O)N2.Cl.ClCCl>>COc1ccc2c(c1)[C@]1(C[C@H]1c1ccc3c(-c4ccc(N5CCN(C)CC5)nc4)n[nH]c3c1)C(=O)N2.Cl.Cl,,CO,ClCCl,,,test
US20080171737A1,COc1ccc(CCl)cc1.O=S1(=O)COc2ccccc2N1>>COc1ccc(CN2c3ccccc3OCS2(=O)=O)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20070259874A1,CI.COc1ccc(C2=NOC(C)(c3noc(=S)[nH]3)C2)cc1OC1CCCC1>>COc1ccc(C2=NOC(C)(c3noc(=S)n3C)C2)cc1OC1CCCC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130281444A1,COC(=O)Cl.O=C(Nc1ccc(C(F)(F)F)cc1)c1cc(-c2ccc(F)cc2F)ccc1O>>O=c1oc2ccc(-c3ccc(F)cc3F)cc2c(=O)n1-c1ccc(C(F)(F)F)cc1,,C1CCOC1,c1ccncc1,Cl,,test
US20100144722A1,COC(=O)C1(c2ccc(Nc3nc(NCC4CC4)cc(-c4ccc(F)cc4)n3)cc2)CCCC1>>O=C(O)C1(c2ccc(Nc3nc(NCC4CC4)cc(-c4ccc(F)cc4)n3)cc2)CCCC1,,CO,,O,[Na+].[OH-],test
US06133319,BrCc1ccccc1.[N-]=[N+]=NC1CCCCC1O>>[N-]=[N+]=N[C@@H]1CCCC[C@H]1OCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20030236401A1,C=CCC(C(=O)OC)c1ccc(OCc2ccccc2)cc1.O=[O+][O-]>>COC(=O)C(CC=O)c1ccc(OCc2ccccc2)cc1,[Zn],CCOC(C)=O,,CC(=O)O,O=C([O-])O.[Na+],test
US20030004181A1,CCOC(=O)CCN(C(=O)c1ccc(NC)c(N)c1)c1ccccc1.N#Cc1ccc(NCC(=O)O)cc1>>CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C#N)cc1)n2C)c1ccccc1,,C1CCOC1,,,,test
US20030144290A1,Cc1ccc(S(N)(=O)=O)cc1.O=C(O)[C@@H]1CC[C@@H](c2nc(-c3cccc(C(F)(F)F)c3)c[nH]2)CC1>>Cc1ccc(S(=O)(=O)NC(=O)[C@@H]2CC[C@@H](c3nc(-c4cccc(C(F)(F)F)c4)c[nH]3)CC2)cc1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20020032202A1,CC(C)N1CCCc2ccccc21.CN(C)C=O>>CC(C)N1c2ccccc2CCC1C=O,,CCCCCC,CCOC(C)=O,O=P(Cl)(Cl)Cl,O=C([O-])O.[Na+],test
US20040142938A1,CC(C)(C)OC(=O)N[C@@H](CO)C(=O)O.O=[N+]([O-])c1cccnc1Cl>>CC(C)(C)OC(=O)N[C@@H](COc1ncccc1[N+](=O)[O-])C(=O)O,,CN(C)C=O,,O,[H-].[Na+],test
US20090275606A1,COC(=O)C1CCCN1S(=O)(=O)Nc1c(Nc2ccc(Br)cc2F)c(F)c(=O)n2c1CCC2>>O=c1c(F)c(Nc2ccc(Br)cc2F)c(NS(=O)(=O)N2CCCC2CO)c2n1CCC2,,C1CCOC1,,CO,[BH4-].[Na+],test
US20070027143A1,CC1Cc2cc3c(cc2C(c2ccc([N+](=O)[O-])cc2)=NN1C(N)=S)OCO3.CCOC(=O)C(C)(C)Br>>CC1=Cc2cc3c(cc2C(c2ccc([N+](=O)[O-])cc2)=NN1C1=NC(=O)C(C)(C)S1)OCO3,,O,,CN(C)C=O,,test
US20120082702A1,NC(=O)c1ccc(N2CCC[C@@H](NC(=O)c3ccccc3)C2)nc1Nc1ccc(N2CCN(C(=O)OCc3ccccc3)CC2)cc1>>NC(=O)c1ccc(N2CCC[C@@H](NC(=O)c3ccccc3)C2)nc1Nc1ccc(N2CCNCC2)cc1,[Pd],CCO,CCOC(C)=O,,,test
US20070167447A1,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].CN(C)C(=O)Cn1c(-c2ccccc2)c(C2CCCCC2)c2ccc(C#N)cc21>>CN(C)C(=O)Cn1c(-c2ccccc2)c(C2CCCCC2)c2ccc(-c3nnn[nH]3)cc21,,CCOC(C)=O,Cc1ccccc1,,,test
US20020045777A1,CCOC(=O)C=CCC1CCC(N(C)C(=O)OC(C)(C)C)CC1>>CCOC(=O)CCC[C@@H]1CC[C@@H](N(C)C(=O)OC(C)(C)C)CC1,[Pd],CO,,,,test
US20120101124A1,CCOC(=O)CCCc1ccc(-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)c2ccn(CC)c12>>CCn1ccc2c(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)ccc(CCCC(=O)O)c21,,CCO,,Cl,[Na+].[OH-],test
US05182203,COC(=O)C(CCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)=NO.O=C(N[C@@H](Cc1ccccc1)C(=O)O)OCc1ccccc1>>COC(=O)C(CCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)=NO.O=C(N[C@@H](Cc1ccccc1)C(=O)O)OCc1ccccc1,,O,,CN(C)C=O,,test
US20060252797A1,Cc1csc(C2(Nc3ccccc3)CCN(Cc3ccccc3)CC2)n1.O=C(O)C(F)(F)F>>Cc1csc(C2(N(C(=O)C(F)(F)F)c3ccccc3)CCN(Cc3ccccc3)CC2)n1,,ClCCl,,CCN(CC)CC,,test
US20070249705A1,CC(C)(C)N(C(=O)[O-])[C@H]1CCN(c2ccc3c(c2)CCC3O)C1=O.CCN(CC)CC.CNC>>CN(C)C1CCc2cc(N3CC[C@H](N(C(=O)[O-])C(C)(C)C)C3=O)ccc21.N,,C1CCOC1,ClCCl,CS(=O)(=O)Cl,,test
US20040122063A1,COC(=O)[C@H]1CC[C@@H](NC(=O)OC(C)(C)C)[C@@H](NC(=O)c2nc3c(s2)CN(C)CC3)C1.Cl.O=C(O)c1cc2cc(Cl)ccc2[nH]1>>COC(=O)[C@H]1CC[C@@H](NC(=O)c2cc3cc(Cl)ccc3[nH]2)[C@@H](NC(=O)c2nc3c(s2)CN(C)CC3)C1.Cl,,C1COCCO1,,,,test
US20120208815A1,Cc1cc(-c2ccncc2N)cc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n1.Nc1ccc(Br)nc1C(=O)O>>Cc1cc(-c2ccncc2NC(=O)c2nc(Br)ccc2N)cc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n1,,CN1CCCC1=O,,ClCCCl,On1nnc2cccnc21,test
US20050176689A1,COC(=O)c1ccc(NC(=O)Nc2ccc3c(c2)C(C)(C)CCC3N(C)C2CC2)cc1>>CN(C1CC1)C1CCC(C)(C)c2cc(NC(=O)Nc3ccc(C(=O)O)cc3)ccc21,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20120129840A1,C1CCNCC1.CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1Cl>>CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1N1CCCCC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20050096380A1,CCOc1cc2c(cc1C(C)=O)C=CCC2(C)C.CI>>CCOc1cc2c(cc1C(=O)CC)C=CCC2(C)C,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20080031852A1,C=CCOC(=O)c1cccn1N.O=Cc1ccc(F)c(Cl)c1>>C=CCOC(=O)c1cccn1NCc1ccc(F)c(Cl)c1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20080004309A1,CCOC(=O)CC(C)=O.O=[N+]([O-])C=Cc1ccccc1>>CCOC(=O)C(C(C)=O)C(C[N+](=O)[O-])c1ccccc1,,CCOC(C)=O,CCOCC,[Na],,test
US20040157902A1,CC(C)(C)OC(=O)NCC(=O)NC(CC(=O)O)c1ccc(-c2ccccc2)cc1.N>>CC(C)(C)OC(=O)NCC(=O)NC(CC(N)=O)c1ccc(-c2ccccc2)cc1,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US20040043987A1,COc1ccccc1B(O)O.Nc1cc(Br)ccc1S(N)(=O)=O>>COc1ccccc1-c1ccc(S(N)(=O)=O)c(N)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US04677123,O=C1c2cccc(O)c2C(=O)c2c(O)cccc21.[Li]c1ccccc1>>O=C1c2c(O)cccc2C(O)(c2ccccc2)c2cccc(O)c21,,C1CCOC1,,,,test
US20140228360A1,CCOC(=O)COc1ccccc1-c1cc[nH]n1.NCC(O)CN1Cc2ccccc2C1>>O=C(COc1ccccc1-c1cc[nH]n1)NCC(O)CN1Cc2ccccc2C1,,CCO,,,,test
US20150210630A1,O=C(NCCl)c1ccccc1C(F)(F)F.O=[N+]([O-])Cc1ncc(Br)cc1Cl>>O=C(NCC(c1ncc(Br)cc1Cl)[N+](=O)[O-])c1ccccc1C(F)(F)F,,CN(C)C=O,,Cl,CC(C)(C)[O-].[K+],test
US20120277212A1,CS(=O)(=O)Cl.OC1CCN(c2ncccn2)CC1>>CS(=O)(=O)OC1CCN(c2ncccn2)CC1,,ClCCl,,CCN(CC)CC,O,test
US06008230,CCc1cnc2c(NC(=O)c3c(Cl)cccc3Cl)cccc2c1CC(=O)O.CI>>CCc1cnc2c(NC(=O)c3c(Cl)cccc3Cl)cccc2c1CC(=O)OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060235029A1,Cc1ccc(C(=O)Nc2nccs2)cc1-c1nc(NCc2ncc[nH]2)nc2c1ccc(=O)n2-c1c(F)cccc1F.Cc1ccc(S(=O)(=O)O)cc1>>Cc1ccc(C(=O)Nc2nccs2)cc1-c1nc(NCc2ncc[nH]2)nc2c1ccc(=O)n2-c1c(F)cccc1F.Cc1ccc(S(=O)(=O)O)cc1,,O,,C1CCOC1,,test
US20160083379A1,CC(CCN(C)C(=O)OC(C)(C)C)c1ccc(N(C)c2ccc(OCc3ccccc3)cc2)cc1>>CC(CCN(C)C)c1ccc(N(C)c2ccc(O)cc2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20010046975A1,CCNC(=O)c1c(Cl)cccc1[Si](C)(C)C.O=[N+]([O-])O>>CCNC(=O)c1c(Cl)ccc([N+](=O)[O-])c1[Si](C)(C)C,,ClCCl,,O=S(=O)(O)O,,test
US20080119473A1,CCOC(=O)c1cccc(-c2cc(-c3ccc(C(C)C)cc3)ccn2)c1>>CC(C)c1ccc(-c2ccnc(-c3cccc(C(=O)O)c3)c2)cc1,,CO,O,[Li+].[OH-],,test
US20020137741A1,CCOC(=O)c1cn(C)c2cnc3c(F)c(N4CCC(O)(c5cccc(C(F)(F)F)c5)CC4)ccc3c2c1=O>>Cn1cc(C(=O)O)c(=O)c2c3ccc(N4CCC(O)(c5cccc(C(F)(F)F)c5)CC4)c(F)c3ncc21,,CCO,O,CC(=O)O,[K+].[OH-],test
US07378240B2,CI.Cc1ccc2nc(-c3ccc4nc(N)sc4c3)sc2c1>>Cc1ccc2nc(-c3ccc4c(c3)sc(N)[n+]4C)sc2c1.[I-],,CS(C)=O,,O,,test
US05034417,CCC(=O)c1ccc([N+](=O)[O-])c(Sc2ccc(F)cc2F)c1.CN(CC(=O)c1ccccc1)c1ccc(F)cc1F.CS(=O)(=O)Cl>>CC(=O)c1ccc(NS(C)(=O)=O)c(N(C)c2ccc(F)cc2F)c1,,c1ccncc1,,,,test
US20060106037A1,CC(O)Cn1cnc(C(N)=O)c1N.CCOC(=O)Cc1ccc(OC)c(OC(F)F)c1>>COc1ccc(Cc2nc3c(ncn3CC(C)O)c(=O)[nH]2)cc1OC(F)F,,CCO,,[Na],,test
US20110046104A1,F[C@H]1CCNC1.O=C(CC(F)(F)F)Nc1ccc(Sc2nc(Cl)cc(Nc3ncn[nH]3)n2)cc1>>O=C(CC(F)(F)F)Nc1ccc(Sc2nc(Nc3nnc[nH]3)cc(N3CC[C@H](F)C3)n2)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,Cl,test
US20020095041A1,C#CC(C)(C)C.O=S(=O)(c1ccc(Br)s1)n1cccc1>>CC(C)(C)C#Cc1ccc(S(=O)(=O)n2cccc2)s1,I[Cu]I,O,,C1CCNCC1,,test
US20120114739A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)c1c(Br)c(N2CCOCC2)nc2c(-c3cnc4ccccc4c3)cnn12>>CC(=O)c1c(N2CCOCC2)nc2c(-c3cnc4ccccc4c3)cnn2c1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20090209607A1,COC(=O)c1cc(-c2ccnn2C)c(C)s1.O=C1CCC(=O)N1Br>>COC(=O)c1cc(-c2c(Br)cnn2C)c(C)s1,,C1CCOC1,,,,test
US20110245205A1,Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C3(C#N)CCC4(CC3)OCCO4)s2)c1.OO>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C3(C(N)=O)CCC4(CC3)OCCO4)s2)c1,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20140051692A1,C=CCCc1cccc(B2OC(C)(C)C(C)(C)O2)c1.C=CCN1CCOc2ccc(-c3c([C@H](OC(C)(C)C)C(=O)OC)c(C)nc4cc(-c5cccc(Br)c5)nn34)c(Cl)c21>>C=CCCc1cccc(-c2cccc(-c3cc4nc(C)c([C@H](OC(C)(C)C)C(=O)OC)c(-c5ccc6c(c5Cl)N(CC=C)CCO6)n4n3)c2)c1,,CN(C)C=O,,O,O=C([O-])[O-].[Na+].[Na+],test
US20100069368A1,Clc1nnc(Cc2ccccc2)c2ccccc12.O=[N+]([O-])c1ccc(C2CCNCC2)cc1>>O=[N+]([O-])c1ccc(C2CCN(c3nnc(Cc4ccccc4)c4ccccc34)CC2)cc1,,CN1CCCC1=O,,O,,test
US20050119489A1,CC1(C)CC(=O)OC1=O.CCc1n[nH]c(CC)c1S(=O)(=O)c1ccc(N)cc1>>CCc1n[nH]c(CC)c1S(=O)(=O)c1ccc(N2C(=O)CC(C)(C)C2=O)cc1,,Cc1ccccc1,c1ccncc1,CCN(CC)CC,,test
US05668157,CN(C)c1ncccc1N.N#CN=C(Oc1ccccc1)Oc1ccccc1>>CN(C)c1ncccc1NC(=NC#N)Oc1ccccc1,,COCCOC,,,,test
US20100056521A1,COc1ccc([N+](=O)[O-])cc1C.N#CCOc1ccc(Cl)cc1>>COc1cc(CC#N)c([N+](=O)[O-])cc1C,,CN(C)C=O,,O,CC(C)(C)[O-].[K+],test
US20140336190A1,Cc1noc(C)c1-c1cc(N)c(N)c(S(=O)(=O)NC2CCCC2)c1.S=C(n1ccnc1)n1ccnc1>>Cc1noc(C)c1-c1cc(S(=O)(=O)NC2CCCC2)c2nc(S)[nH]c2c1,,CN(C)C=O,,,,test
US20100048532A1,COCCn1c(C)nc2cc(C(=O)OC)c(CCC(=O)c3ccccc3)c(O)c21>>COCCn1c(C)nc2cc(C(=O)OC)c(CCC(O)c3ccccc3)c(O)c21,,CCO,,[BH4-].[Na+],,test
US20120258949A1,NOC1CCCCO1.O=C(O)/C=C/c1ccc2c(c1)C(=O)CC1(CN(Cc3ccc(F)cc3)C1)O2>>O=C(/C=C/c1ccc2c(c1)C(=O)CC1(CN(Cc3ccc(F)cc3)C1)O2)NOC1CCCCO1,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US08178548B2,COC(=O)c1cc(NS(C)(=O)=O)ccc1/C=C/c1cc(-n2ccc(=O)[nH]c2=O)cc(C(C)(C)C)c1OC>>COC(=O)c1cc(NS(C)(=O)=O)ccc1CCc1cc(-n2ccc(=O)[nH]c2=O)cc(C(C)(C)C)c1OC,[Pd],C1CCOC1,CO,,,test
US20150152108A1,Cc1cc(-c2ccc3c(n2)N[C@H]2CCN3C2)ccn1.Nc1ccc2c(c1)OCO2.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>Cc1cc(-c2ccc3c(n2)N(C(=O)Nc2ccc4c(c2)OCO4)[C@H]2CCN3C2)ccn1,,C1CCOC1,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US06310208B1,CCCBr.O=C1C[C@H]2CCNC[C@H]2c2ccc(F)cc21>>CCCN1CC[C@@H]2CC(=O)c3cc(F)ccc3[C@@H]2C1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100174093A1,CCO/C=C(\C(=O)OCC)C(=O)C(F)F.CNN>>CCOC(=O)c1cn(C)nc1C(F)F,,Cc1ccccc1C,,O,,test
US04829079,C=CCOC1CCC(=O)N1.O=S(=O)(Cl)c1ccccc1>>C=C(C)OC1CCC(=O)N1S(=O)(=O)c1ccccc1,,CCOCC,,CCOC(C)=O,,test
US05574042,CS(=O)(=O)OCCc1c(Cl)cccc1Cl.Cc1cn2cccc(O)c2n1>>Cc1cn2cccc(OCCc3c(Cl)cccc3Cl)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050009859A1,O=C(Nc1c(C(F)(F)F)n[nH]c1-c1ccccc1)c1ccccc1.O=[N+]([O-])c1ccccc1>>FC(F)(F)c1n[nH]c2c1nc(-c1ccccc1)c1ccccc12,,O=[N+]([O-])c1ccccc1,,O=P(Cl)(Cl)Cl,,test
US20060116376A1,CC(C)(C)OC(=O)N1CCC(Oc2nn(-c3ccccc3F)c3cccc(F)c23)CC1.Cl>>Cl.Fc1ccccc1-n1nc(OC2CCNCC2)c2c(F)cccc21,,C1COCCO1,CCOC(C)=O,,,test
US20110306591A1,Cc1ccc(S(=O)(=O)NC2CC(Oc3ncccc3C3CCN(C(=O)OC(C)(C)C)CC3)C2)cc1.Cl>>Cc1ccc(S(=O)(=O)NC2CC(Oc3ncccc3C3CCNCC3)C2)cc1.Cl,,CO,,,,test
US20080004274A1,CCCCBr.COC1(OC)C(=O)Nc2ccc(I)cc21>>CCCCN1C(=O)C(OC)(OC)c2cc(I)ccc21,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US04562186,CC(C)OC(=O)Cc1nc(C(=O)c2ccc(F)cc2)no1>>O=C(O)Cc1nc(C(=O)c2ccc(F)cc2)no1,,O=S(=O)(O)O,,,,test
US06262040B1,CCc1nn(C2CCCC2)c2cc(C(=O)Nc3c(Cl)cncc3Cl)ccc12.CI>>CCc1nn(C2CCCC2)c2cc(C(=O)N(C)c3c(Cl)cncc3Cl)ccc12,,CN(C)C=O,O,[Na],,test
US20060122178A1,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1nc2ccccc2s1>>Cc1ccc(S(=O)(=O)N=c2[nH]c3ccccc3s2)cc1,,c1ccncc1,,,,test
US20090286768A1,C[Mg]Br.O=C(c1ccc(Cl)cc1)c1cccc(F)c1>>CC(O)(c1ccc(Cl)cc1)c1cccc(F)c1,,C1CCOC1,,,,test
US20110319378A1,C=CCBr.O=C1CC[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N1CC1CC1>>C=CC[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20130252986A1,ClCc1ccccn1.N#Cc1cc(COc2ccnc(=O)[nH]2)ccc1Oc1ccc(Cl)c(C(F)(F)F)c1>>N#Cc1cc(COc2ccn(Cc3cccnc3)c(=O)n2)ccc1Oc1ccc(Cl)c(C(F)(F)F)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20090099155A1,CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(SCCCc3ccc4c(c3)C(C)(C)C(=O)N4)c2CC1>>CC1(C)C(=O)Nc2ccc(CCCSc3c(Cl)ccc4c3CCNCC4)cc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150299194A1,CCOCc1nc2c(NC(c3ccccc3)(c3ccccc3)c3ccccc3)nc3ccccc3c2n1CC(C)(C)OCCNC(=O)OC(C)(C)C>>CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OCCN,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20130217709A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[Si](C)(C)CCOC(=O)N[C@@H]1CNC[C@H]1c1cccc(F)c1.ClCCl>>CCCOC(=O)N[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1c1cccc(F)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150175561A1,C#CC[C@H](NC(=O)OC(C)(C)C)C(N)=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>C#CC[C@H](NC(=O)OC(C)(C)C)C(N)=S,,C1CCOC1,,,,test
US20120264749A1,Cc1cnc(C2CNCC3(CCN(C(=O)c4ccc(OC(C)C)c(C)c4)CC3)O2)o1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>Cc1cnc(C2CN(CC(F)(F)F)CC3(CCN(C(=O)c4ccc(OC(C)C)c(C)c4)CC3)O2)o1,,CCO,,Cl,O=C([O-])O.[Na+],test
US07807709B2,COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2C=O)C(C)C)ccc1OC.NCC1CC1>>COCCCOc1cc(C(=O)N(C[C@@H]2CNC[C@H]2CNCC2CC2)C(C)C)ccc1OC,,CO,ClCCl,[BH4-].[Na+],,test
US20030130523A1,Cc1cc(C)cc(N)c1.O=C(O)Cc1ccc(O)cc1>>Cc1cc(C)cc(NC(=O)Cc2ccc(O)cc2)c1,,Cc1ccccc1C,,,,test
US20100286114A1,Nc1ccccc1N.O=C(O)c1cc(Br)ccc1Cl>>Clc1ccc(Br)cc1-c1nc2ccccc2[nH]1,,[Na+],[OH-],CS(=O)(=O)O,,test
US20110172442A1,COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C(C)=Cc1ccccc1>>CC(=Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O,,CO,,[Na+].[OH-],,test
US05972965,COc1cccc(C(O)C2CCOC2=O)c1>>COc1cccc(CC2CCOC2=O)c1,[Pd],CCO,,,,test
US20080275027A1,C1CCNCC1.CC(C)(C)OC(=O)N1CCN(c2ccc(OCCCCl)cc2)C(=O)C1>>CC(C)(C)OC(=O)N1CCN(c2ccc(OCCCN3CCCCC3)cc2)C(=O)C1,,CC(C)=O,,[I-].[Na+],,test
US20070197617A1,C1COCCN1.COC(=O)[C@H](NC(=O)OC(C)(C)C)c1ccc(OCCOS(C)(=O)=O)cc1>>COC(=O)[C@H](NC(=O)OC(C)(C)C)c1ccc(OCCN2CCOCC2)cc1,,CCO,,,,test
US20040018192A1,Nc1ncccn1.O=S(=O)(O)Cl>>Nc1ncc(S(=O)(=O)Cl)cn1,,O,,O=S(Cl)Cl,,test
US20110144129A1,CC[C@]1(C(=O)N2C[C@@H]3C[C@H]2CN3)CC[C@@H](N[C@@H]2CCOC[C@H]2OC)C1.FC(F)(F)c1ccnc(Cl)c1>>CC[C@]1(C(=O)N2C[C@@H]3C[C@H]2CN3c2cc(C(F)(F)F)ccn2)CC[C@@H](N[C@H]2CCOC[C@H]2OC)C1,,CS(C)=O,,CCN(CC)CC,Cl,test
US04565817,CCOC(C)=O.Cn1c(=O)c2c(ncn2CC(N)=NO)n(C)c1=O>>Cc1nc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)no1,,CO,,C[O-].[Na+],,test
US08754094B2,CO.NC(=O)NCCCCCC(=O)O>>COC(=O)CCCCCNC(N)=O,,CO,c1ccccc1,C[Si](C)(C)C=[N+]=[N-],,test
US20090247746A1,COCCl.O=[N+]([O-])c1cccc2cc(-c3nccs3)[nH]c12>>COCn1c(-c2nccs2)cc2cccc([N+](=O)[O-])c21,,C1CCOC1,CN(C)C=O,O,[H-].[Na+],test
US05432198,BrCc1ccccc1.CC(C)(C)OC(=O)c1cc(OCc2ccccc2)c(C(=O)c2c(OCc3ccccc3)cccc2C(=O)O)c(OCc2ccccc2)c1>>CC(C)(C)OC(=O)c1cc(OCc2ccccc2)c(C(=O)c2c(OCc3ccccc3)cccc2C(=O)OCc2ccccc2)c(OCc2ccccc2)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040048897A1,Nc1ccc(Cl)c(S(=O)(=O)N2CCC(N3CCCCC3)CC2)c1O.O=c1c(Cl)c(Cl)c1=O>>O=c1c(Cl)c(Nc2ccc(Cl)c(S(=O)(=O)N3CCC(N4CCCCC4)CC3)c2O)c1=O,,C1CCOC1,,,,test
US20090257979A1,CCOC(=O)C(=Cc1ccc(OC)cc1)c1ccccn1>>COc1ccc(C=C(C(=O)O)c2ccccn2)cc1,,C1CCOC1,O,[Na+].[OH-],,test
US05462952,Cc1ccc(Cl)c(Nc2ccccc2C(=N)NN)c1Cl.S=C=S>>Cc1ccc(Cl)c(Nc2ccccc2-c2n[nH]c(=S)s2)c1Cl,,CO,,,,test
US03963718,Cl.NC1=NCC(c2ccccc2Cl)N1CCCl>>Cl.Clc1ccccc1C1CN=C2NCCN21,,CO,,[Na],,test
US20130116232A1,C1=COCCC1.CC1=C(c2cccc(O)c2)C(c2ccc(I)cc2)Oc2ccc(O)cc21.Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1>>CC1=C(c2cccc(OC3CCCCO3)c2)C(c2ccc(I)cc2)Oc2ccc(OC3CCCCO3)cc21,,ClCCl,,,,test
US20060089359A1,Cc1cc(Nc2nn(-c3ccc(C(C)(C)C)cc3)c(=O)c3ccc(N)cc23)n(C(C)(C)C)n1>>Cc1cc(Nc2nn(-c3ccc(C(C)(C)C)cc3)c(=O)c3ccc(N)cc23)[nH]n1,,CO,,Cl,,test
US06395737B1,COC(=O)[C@@H](NC(=O)C(Cc1ccc(C#N)cc1)C(=O)N(C)Cc1ccccc1)C1CCCCC1>>CN(Cc1ccccc1)C(=O)C(Cc1ccc(C#N)cc1)C(=O)N[C@H](C(=O)O)C1CCCCC1,,ClCCl,O=C(O)C(F)(F)F,CC#N,,test
US20070173501A1,CC1(C)O/C(=C2/C(=O)Nc3cc(F)ccc32)C=C1Br.OCCN1CCNCC1>>CC1(C)O/C(=C2/C(=O)Nc3cc(F)ccc32)C=C1N1CCN(CCO)CC1,,CCOC(C)=O,CN(C)C=O,,,test
US04143145,BrBr.COC(=O)c1cccc(COCC(=O)c2ccccc2)c1>>COC(=O)c1cccc(COC(Br)C(=O)c2ccccc2)c1,,ClCCl,,,,test
US20090098218A1,CCOC(=O)CC(=O)NCC1(C(=O)OC)CN(C(=O)OC(C)(C)C)C1>>COC(=O)C1C(=O)NCC2(CN(C(=O)OC(C)(C)C)C2)C1=O,,CO,Cc1ccccc1,[Na],,test
US20100197716A1,CC1(C)CNc2ccccc21.O=[N+]([O-])c1ccccc1F>>CC1(C)CN(c2ccccc2[N+](=O)[O-])c2ccccc21,,ClCCl,,,,test
US20100240669A1,C/C(=N/O)c1ccc(Nc2ccc(OC(F)F)cc2)cc1>>CC(N)c1ccc(Nc2ccc(OC(F)F)cc2)cc1,[Ni],N,,[H][H],,test
US20120302566A1,COC(=O)CC1COc2cc(O)cc(C)c21.O[C@H]1CCc2c1cccc2C(F)(F)F>>COC(=O)CC1COc2cc(O[C@@H]3CCc4c3cccc4C(F)(F)F)cc(C)c21,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100227858A1,CCOC(=O)n1c(C(=O)OC(C)(C)C)cc2ccc(-c3nc(CS(C)(=O)=O)cc(N4CCOC[C@@H]4C)n3)cc21>>CCOC(=O)c1cc2ccc(-c3nc(CS(C)(=O)=O)cc(N4CCOC[C@@H]4C)n3)cc2[nH]1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20010027196A1,CSc1cc(-c2ccco2)nc(N)n1.O=C1CCC(=O)N1I>>CSc1nc(N)nc(-c2ccco2)c1I,,CC(=O)O,,,,test
US20130196993A1,Cc1cccc(Cl)[n+]1[O-].O=[N+]([O-])O>>Cc1cc([N+](=O)[O-])cc(Cl)[n+]1[O-],,O=S(=O)(O)O,,,,test
US04620865,CN.O=C(O)c1cnn(-c2ccccc2)c1Br>>CNC(=O)c1cnn(-c2ccccc2)c1Br,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US04867915,CS(=O)(=O)Cl.OCC#CCOC1CCCCO1>>CS(=O)(=O)OC#CCCOC1CCCCO1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20060058309A1,COc1cc2ccccc2nc1C>>COc1cc2c(nc1C)CCCC2,[Pd],O=C(O)C(F)(F)F,,[H][H],,test
US20090062529A1,CC(C)(C)OC(=O)NNC(=O)C(CC(O)CO)c1cc(F)c(F)c(F)c1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCC(O)CC(C(=O)NNC(=O)OC(C)(C)C)c2cc(F)c(F)c(F)c2)cc1,,c1ccncc1,,,,test
US20120142705A1,CC(C)(O)Cn1ccc(N)n1.O=C(O)C(CC1CCCC1)N1C(=O)Cc2ccccc21>>CC(C)(O)Cn1ccc(NC(=O)C(CC2CCCC2)N2C(=O)Cc3ccccc32)n1,,ClCCl,O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20040043982A1,Cc1cc(-c2nnc3c4ccccc4c(OCc4ccc(C5(O)CCN(C(=O)OC(C)(C)C)CC5)nc4)nn23)no1>>Cc1cc(-c2nnc3c4ccccc4c(OCc4ccc(C5(O)CCNCC5)nc4)nn23)no1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080087887A1,C[Si](C)(C)C#Cc1ccc(N)cc1.[I-]>>C[Si](C)(C)C#Cc1ccc(I)cc1,,Cl,,O=N[O-].[Na+],,test
US05668279,Cc1ccc(-c2n[nH]c(=O)c3ccccc23)cc1>>Cn1ncc2ccccc2c1=O,,CCOC(C)=O,,Cc1ccccc1,[Na+].[OH-],test
US20060035938A1,CCOC=C(C(=O)OCC)C(=O)OCC.N.O=C=Nc1cccc(C(F)(F)F)c1>>O=C(O)c1c[nH]c(=O)n(-c2cccc(C(F)(F)F)c2)c1=O,,CC#N,O,C,C[O-].[Na+],test
US20060106020A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1nc(N)nc(C)c1I>>COc1nc(NC(=O)OC(C)(C)C)nc(C)c1I,CN(C)c1ccncc1,C1CCOC1,,,,test
US20150239847A1,Nc1ccn(-c2ccccc2Cl)n1.O=C1CCC(=O)N1Br>>Nc1nn(-c2ccccc2Cl)cc1Br,,C1CCOC1,,,,test
US20130053381A1,COC(=O)c1cc(-n2ccnc2C)c(C(F)(F)F)cc1[N+](=O)[O-]>>COC(=O)c1cc(-n2ccnc2C)c(C(F)(F)F)cc1N,[Pd],CO,,,,test
US05639782,COc1cc(C2CSC(=S)S2)cc(OC)c1OC.COc1cc(C=O)cc(I)c1O>>COc1cc([C@@H]2SC[C@@H](c3cc(OC)c(OC)c(OC)c3)S2)cc(I)c1O,,O,c1ccccc1,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US05438035,CC(C)(C)N1CC(=O)Nc2ccc(C#C[Si](C)(C)C)cc2C1=O>>C#Cc1ccc2c(c1)C(=O)N(C(C)(C)C)CC(=O)N2,,CO,,[Na+].[OH-],,test
US20100234340A1,CCOC(=O)c1noc2c1CNCC2.O=C=Nc1ccc(Cl)c(Cl)c1>>CCOC(=O)c1noc2c1CN(C(=O)Nc1ccc(Cl)c(Cl)c1)CC2,,Cc1ccccc1,,,,test
US08003783B2,C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=O.O=Cc1ccco1>>CC12CCC3c4ccc(O)cc4CCC3C1CC(=Cc1ccco1)C2=O,,CCO,O,CC(=O)O,[K+].[OH-],test
US20120165310A1,C=CS(C)(=O)=O.Nc1ncnc2c1c(-c1cccc(OCC34CCC(CC3)O4)c1)cn2C1CCNCC1>>CS(=O)(=O)CCN1CCC(n2cc(-c3cccc(OCC45CCC(CC4)O5)c3)c3c(N)ncnc32)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US05506190,CCCCN.O=C1C2=C(CCCC2)C(=O)N1c1cc(OC2CCCC2)c(Cl)cc1F>>CCCCNC(=O)C1=C(C(=O)Nc2cc(OC3CCCC3)c(Cl)cc2F)CCCC1,,c1ccccc1,,,,test
US04482560,CC(=O)C1(c2ccccc2)CCNCC1.CN1C(=O)CCc2cc(OCCBr)ccc21>>CC(=O)C1(c2ccccc2)CCN(CCOc2ccc3c(c2)CCC(=O)N3C)CC1,,CN(C)C=O,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20140206618A1,COC(=O)C1CC(=O)C(=CN(C)C)C1.N=C(N)N>>COC(=O)C1Cc2cnc(N)nc2C1,,CO,,Cl,C[O-].[Na+],test
US20150252044A1,CC(C)COC(=O)c1ccc2cncc(CC(C)C)c2n1>>CC(C)Cc1cncc2ccc(C(=O)O)nc12,,C1COCCO1,O,Cl,[Li+].[OH-],test
US20100273919A1,CCCCCC(CCC)COS(=O)(=O)C(F)(F)F.Cc1cncc(C)c1-c1c(C)cc(C=Cc2ccc(C(C#N)C#N)cc2)cc1C>>CCCCCC(CCC)CN1C=C(C)C(=c2c(C)cc(=CC=c3ccc(=C(C#N)C#N)cc3)cc2C)C(C)=C1,,CO,ClCCl,C[O-].[Na+],,test
US20080255124A1,CI.N#Cc1ccc(N(CCNc2ncccn2)CC(F)(F)F)cc1C(F)(F)F>>CN(CCN(CC(F)(F)F)c1ccc(C#N)c(C(F)(F)F)c1)c1ncccn1,,CN(C)C=O,,[H-].[Na+],,test
US20100075994A1,CCOC(=O)C#CCSc1ccccc1.NC1=NC[C@@H](COc2ccc(C3CCCCC3)cc2)O1>>O=c1cc(CSc2ccccc2)n2c(n1)O[C@H](COc1ccc(C3CCCCC3)cc1)C2,,ClC(Cl)Cl,,,,test
US04321372,NC(N)=S.O=C(C(Br)C1CCCCC1)C(Br)C1CCCCC1>>Nc1nc(C2CCCCC2)cs1,,CCO,,,,test
US04775753,CCN(CC)[C@@H](C)CO.Cl.O=S(Cl)Cl>>CCN(CC)[C@@H](C)CCl.Cl,,O=S(Cl)Cl,,,,test
US20070112033A1,CCOC(=O)c1cc2ncn(CCC(C)(C)NC(=O)OC(C)(C)C)c2cc1Cl>>CCOC(=O)c1cc2ncn(CCC(C)(C)N)c2cc1Cl,,Cl,,,,test
US04962224,CCCCOc1ccc2c(C(F)(F)F)c(OC)ccc2c1C(=O)N(C)CC(=O)OC>>CCCCOc1ccc2c(C(F)(F)F)c(OC)ccc2c1C(=O)N(C)CC(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20160016908A1,CC(=O)N1c2ccc(C#N)cc2[C@H](Nc2cccc(CO[Si](C)(C)C(C)(C)C)c2)[C@@H](C)[C@@H]1C1CC1>>CC(=O)N1c2ccc(C#N)cc2[C@H](Nc2cccc(CO)c2)[C@@H](C)[C@@H]1C1CC1,,C1CCOC1,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04425333,CC(=O)SCCC(=O)N1[C@H](C(=O)O)CS[C@@H]1c1ccccc1O.N[C@@H](CO)C(=O)O>>CC(=O)SCCC(=O)N1[C@H](C(=O)N[C@@H](CO)C(=O)O)CS[C@@H]1c1ccccc1O,,C1CCOC1,CCN(CC)CC,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20070276138A1,CCOC(=O)[C@H](Cc1ccc(OCCCOc2ccc(C(=O)c3ccc(F)cc3)cc2)cc1)OC>>CCOC(=O)[C@H](Cc1ccc(OCCCOc2ccc(C(O)c3ccc(F)cc3)cc2)cc1)OC,,CO,,[BH4-].[Na+],,test
US20160264536A1,CO.Clc1cc(N2CCCC2)nc(Cl)n1>>COc1cc(N2CCCC2)nc(Cl)n1,,C1CCOC1,,O,C[O-].[Na+],test
US20050020605A1,CC1(N2CCC(C(Oc3ccccn3)c3ccc(Br)cc3)CC2)CCNCC1.O=C(O)c1ccnc2ccccc12>>CC1(N2CCC(C(Oc3ccccn3)c3ccc(Br)cc3)CC2)CCN(C(=O)c2ccnc3ccccc23)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100210696A1,CN(Cc1cc(Sc2ccc(Cl)nc2)n(-c2ccccc2Cl)n1)C(=O)OC(C)(C)C.Cl>>CNCc1cc(Sc2ccc(Cl)nc2)n(-c2ccccc2Cl)n1.Cl,,CCOC(C)=O,CO,,,test
US05102667,C1COCCN1.O=C(CF)c1ccccc1>>O=C(CN1CCOCC1)c1ccccc1,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100152190A1,CC(C)(C)[Si](C)(C)OCCBr.Nc1cc[nH]c(=O)c1>>CC(C)(C)[Si](C)(C)OCCn1ccc(N)cc1=O,,CN(C)C=O,,O,[H-].[Na+],test
US20110070317A1,CN(C(=O)OC(C)(C)C)[C@@H]1CCCN(c2c(Cl)cnc3[nH]cc(NC(=O)C4CC4)c23)C1.ClCCl>>CN[C@@H]1CCCN(c2c(Cl)cnc3[nH]cc(NC(=O)C4CC4)c23)C1.Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100010053A1,CCOC(=O)CCc1c[nH]c2cc(-c3noc(-c4cnc(OC(C)C)c(Cl)c4)n3)ccc12>>CC(C)Oc1ncc(-c2nc(-c3ccc4c(CCC(=O)O)c[nH]c4c3)no2)cc1Cl,,CC(C)O,O,Cl,[Na+].[OH-],test
US20040092533A1,FC(F)(F)c1ccn2c(-c3cccc(Br)n3)cnc2n1.N#Cc1ccccc1B(O)O>>N#Cc1ccccc1-c1cccc(-c2cnc3nc(C(F)(F)F)ccn23)n1,,CC(=O)N(C)C,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US05084085,Cc1nn(-c2cc(N)c(Cl)cc2Cl)c(=O)n1C(F)F.Cl.O=S=O>>Cc1nn(-c2cc(S(=O)(=O)Cl)c(Cl)cc2Cl)c(=O)n1C(F)F,Cl[Cu]Cl,CC(=O)O,O,O=N[O-].[Na+],,test
US20150031727A1,CCC(CC)N(Cc1cccc(C(=O)Nc2sc3c(c2C(=O)Nc2ccc(C(C)(C)C(=O)O)nc2)CCCC3)c1)C(=O)CCC(C)(C)C(=O)OC>>CCC(CC)N(Cc1cccc(C(=O)Nc2sc3c(c2C(=O)Nc2ccc(C(C)(C)CO)nc2)CCCC3)c1)C(=O)CCC(C)(C)C(=O)OC,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US06262103B1,CSc1sc(-c2ccccn2)c2c1C(=O)CC(C)(C)C2.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1sc(-c2ccccn2)c2c1C(=O)CC(C)(C)C2,,ClCCl,ClCCl,,,test
US20120046268A1,CC(C)(C)OC(=O)NC1(C(=O)O)CC1.O=C(NC1CNCC(c2ccc(C(F)(F)F)cc2)C1)c1ccccc1>>CC(C)(C)OC(=O)NC1(C(=O)N2CC(NC(=O)c3ccccc3)CC(c3ccc(C(F)(F)F)cc3)C2)CC1,CN(C)c1ccncc1,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20040092582A1,N#Cc1ccc(F)cc1.Sc1ccccc1>>N#Cc1ccc(Sc2ccccc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100209827A1,O=C(Cl)CC12CC3CC(CC(C3)C1)C2.O=S(=O)([O-])CC(O)(C(F)(F)F)C(F)(F)F.c1ccc([S+](c2ccccc2)c2ccccc2)cc1>>O=C(CC12CC3CC(CC(C3)C1)C2)OC(CS(=O)(=O)[O-])(C(F)(F)F)C(F)(F)F.c1ccc([S+](c2ccccc2)c2ccccc2)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20110065727A1,Cl.OCc1ccccc1-c1ccc2nc(-c3ccoc3)cn2c1>>Cl.OCc1ccccc1-c1ccc2nc(-c3ccoc3)cn2c1,,CC(C)O,ClCCl,,,test
US06368608B1,CCN.O=C(Cl)c1ccc(I)cc1>>CCNC(=O)c1ccc(I)cc1,,C1CCOC1,ClCCl,O,,test
US07202221B2,CC(C)(C)OC(=O)NCCCNc1cc2c(cc1F)c(=O)c(C(=O)O)cn2C1CC1>>NCCCNc1cc2c(cc1F)c(=O)c(C(=O)O)cn2C1CC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20130109670A1,Nc1ccc(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)cc1.S=C1NCCN1>>c1cc(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)ccc1NC1=NCCN1,Cl[Hg]Cl,CN(C)C=O,,,,test
US05079023,C=COCC(C)C.OCc1ccccc1>>CC(C)COC(C)OCc1ccccc1,Cl,,,O=C([O-])[O-].[Na+].[Na+],,test
US04814342,COC(=O)[C@@H](N)CSC.O=C(O)[C@H](Cc1ccccc1)NC(=O)N1CCOCC1>>CSC[C@H](N)C(=O)O.O=C(O)[C@H](Cc1ccccc1)NC(=O)N1CCOCC1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US05494888,COc1cc(OC)nc(Oc2cccc(Cl)c2C(=O)O)n1.c1cc(Sc2ccncc2)ccn1>>COc1cc(OC)nc(Oc2cccc(Cl)c2C(=O)OSc2ccncc2)n1,,Cc1ccccc1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20120277573A1,COCCOCCOCCOCCOCC(F)(F)C(F)(F)C(F)(F)C(F)(F)CN1C(=O)c2ccccc2C1=O>>COCCOCCOCCOCCOCC(F)(F)C(F)(F)C(F)(F)C(F)(F)CN,,CCO,,NN,,test
US04472582,Cc1ccccc1N.O=C(O)c1ccc(C(=O)O)c(Br)c1>>Cc1ccccc1Nc1cc(C(=O)O)ccc1C(=O)O,,CCOCCO,,O,O=C([O-])[O-].[K+].[K+],test
US06084133,ClP(C1CCCCC1)C1CCCCC1>>C1CCC(PC2CCCCC2)CC1,[Zn],CN(C)C=O,,Cc1ccccc1,Cl,test
US20140206663A1,CCOC(=O)C(C)N1C(=O)COc2cc(C)c([N+](=O)[O-])cc21.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)C(C)N1C(=S)COc2cc(C)c([N+](=O)[O-])cc21,,Cc1ccccc1,,,,test
US20020049204A1,CC1(C)OC(=O)Nc2ccc(-c3cccc(Br)c3)cc21.CCCC[Sn](CCCC)(CCCC)c1nccs1>>CC1(C)OC(=O)Nc2ccc(-c3cccc(-c4nccs4)c3)cc21,,CN(C)C=O,,,,test
US20070155805A1,CCCC(CCSc1nc(C)c(CC(=O)OCC)s1)c1sc2cc(C(F)(F)F)ccc2c1C>>CCCC(CCSc1nc(C)c(CC(=O)O)s1)c1sc2cc(C(F)(F)F)ccc2c1C,,C1CCOC1,CO,[Na+].[OH-],,test
US20020169200A1,CCOC(=O)CCCl.c1cnc2nc(CCCc3ccc4[nH]ccc4c3)ccc2c1>>CCOC(=O)CCn1ccc2cc(CCCc3ccc4cccnc4n3)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20030139442A1,N#Cc1cc(Br)ccc1N=C1CCCN1Cc1ccc(F)cc1>>Nc1c2c(nc3ccc(Br)cc13)N(Cc1ccc(F)cc1)CC2,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20050113379A1,COC(=O)N1C[C@H](OCCF)[C@H](n2cc(C)c3nc(-c4ccc(C(C)C)nc4OC)c(C)cc32)C1>>COc1nc(C(C)C)ccc1-c1nc2c(C)cn([C@@H]3CN(C)C[C@@H]3OCCF)c2cc1C,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120329877A1,BrCc1ccc(Br)cc1.CC(C)COC1=CC(=O)CC1>>CC(C)COC1=CC(=O)C(Cc2ccc(Br)cc2)C1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20050026174A1,COC(=O)c1ccc([N+](=O)[O-])c(N)n1>>COC(=O)c1ccc(N)c(N)n1,,CO,,,,test
US20090042852A1,CC(C)(C)OC(=O)N1CCC(C(=O)NS(=O)(=O)c2ccc(Cl)s2)CC1.Cl>>Cl.O=C(NS(=O)(=O)c1ccc(Cl)s1)C1CCNCC1,,C1CCOC1,,,,test
US20080064712A1,BrCC1CC1.COc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(OCCCc5ccccc5)[C@@H](C2)NCC[C@]314.Cl>>COc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(OCCCc5ccccc5)[C@@H](C2)N(CC2CC2)CC[C@]314.Cl,,O,,O=C([O-])[O-].[K+].[K+],,test
US20100197609A1,C[C@H](NC(=O)CCNC(=O)OC(C)(C)C)C(=O)OCCOc1ccc(-c2c(C#N)c(SCc3csc(-c4ccc(Cl)cc4)n3)nc(N3CCCC3)c2C#N)cc1.Cl>>C[C@H](NC(=O)CCN)C(=O)OCCOc1ccc(-c2c(C#N)c(SCc3csc(-c4ccc(Cl)cc4)n3)nc(N3CCCC3)c2C#N)cc1.Cl,,CCOCC,ClCCl,,,test
US04317920,CC(C(=O)O)c1cccc(Oc2ccccc2)c1OS(C)(=O)=O>>CC(C(=O)O)c1cccc(Oc2ccccc2)c1,[Pd],CCN(CC)CC,,CO,[H][H],test
US20070276000A1,COc1ccc(C(=O)Cc2ccccc2)c(C#CCC(C)C)c1>>COc1ccc2c(O)c(-c3ccccc3)c(CC(C)C)cc2c1,,Cc1ccccc1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20090203667A1,CCOC(=O)CCc1ccccc1.[I-]>>CCOC(=O)/C=C(\I)c1ccccc1,,CC(=O)O,,O,,test
US20090203703A1,CCOC(=O)c1sc2nc(C)[nH]c(=O)c2c1C.ClCc1ccccc1>>CCOC(=O)c1sc2nc(C)n(Cc3ccccc3)c(=O)c2c1C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100048648A1,CC(C)Cc1ccc(C(=O)O)s1.[Li]C>>CC(=O)c1ccc(CC(C)C)s1,,CCOCC,,,,test
US20120053175A1,COc1cc(-c2cnc3c(c2)CC(=O)N3)cc(OC)c1OC.N#Cc1ccc(C=O)cc1>>COc1cc(-c2cnc3c(c2)C(=Cc2ccc(C#N)cc2)C(=O)N3)cc(OC)c1OC,,Cc1ccccc1,,CCN(CC)CC,,test
US20090042852A1,COC(=O)C1CCN(c2ccc(I)c(Cl)n2)CC1.O=C1CCC(=O)N1Cl>>COC(=O)C1CCN(c2nc(Cl)c(I)cc2Cl)CC1,,CC#N,,,,test
US20150274656A1,C=CC[C@@H]1[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@@H](COCc2ccccc2)N1O.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=CC[C@@H]1[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@@H](COCc2ccccc2)N1C(=O)OC(C)(C)C,[Zn],CC(=O)O,CO,CCN(C(C)C)C(C)C,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(-c2ccc(O)cc2)c2ccnn12.CCOC(=O)CBr>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(-c2ccc(OCC(=O)OCC)cc2)c2ccnn12,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US06096781,S=C(Cc1ccccc1)c1ccccc1>>c1ccc(-c2cc3ccccc3s2)cc1,,O,,,,test
US20150252038A1,C[C@H]1[C@@H](Oc2cc(F)c(C(=O)OC(C)(C)C)cc2C2CC2)CCCN1Cc1ccccc1>>C[C@@H]1NCCC[C@@H]1Oc1cc(F)c(C(=O)OC(C)(C)C)cc1C1CC1,[Pd],CO,,O=C[O-].[NH4+],,test
US20130261114A1,C#CC(O)(c1ccccc1)C1CN2CCC1CC2.COC(=O)c1ccc(Br)cc1>>COC(=O)c1ccc(C#CC(O)(c2ccccc2)C2CN3CCC2CC3)cc1,[Cu]I,C1CCOC1,,CCN(CC)CC,,test
US20080182874A1,COC(=O)CCN1CCN(c2ccc3c(C(=O)NCCC45CC6CC(CC(C6)C4)C5)c(Cl)ccc3n2)CC1>>O=C(O)CCN1CCN(c2ccc3c(C(=O)NCCC45CC6CC(CC(C6)C4)C5)c(Cl)ccc3n2)CC1,,CO,O,Cl,[Na+].[OH-],test
US20080214615A1,CNc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O.ClCCl.O=C=Nc1cccc2ccccc12>>CN(Cc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O)C(=O)Nc1cccc2ccccc12,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20120101123A1,CCOC(=O)CCCn1ccc2c(-c3cnc(-c4ccc(OC(C)C)c(Cl)c4)s3)ccnc21>>CC(C)Oc1ccc(-c2ncc(-c3ccnc4c3ccn4CCCC(=O)O)s2)cc1Cl,,CN(C)C=O,,Cl,[Na+].[OH-],test
US20040220186A1,CCN(CC)CCCl.O=C(Cc1ccccc1O)OCc1ccccc1>>CCN(CC)CCOc1ccccc1CC(=O)OCc1ccccc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20070129346A1,COC(=O)CBr.O=C(OCc1ccccc1)N1CC[C@H](NC2CCCCC2)C1>>COC(=O)CN(C1CCCCC1)[C@H]1CCN(C(=O)OCc2ccccc2)C1,,C1CCOC1,,[H-].[Na+],,test
US20130079338A1,CS(=O)(=O)Cl.OCc1cnc(Nc2ccc(Cl)cc2)nc1>>ClCc1cnc(Nc2ccc(Cl)cc2)nc1,,ClCCl,,CCN(CC)CC,,test
US20020091273A1,COc1cc(N)c(Cl)cc1Cl.COc1cc2cc3c(Cl)ncnc3cc2cc1OCCN1CCOCC1.Cl>>COc1cc(Nc2ncnc3cc4cc(OCCN5CCOCC5)c(OC)cc4cc23)c(Cl)cc1Cl.Cl.Cl,,CC(C)O,,c1ccncc1,,test
US06159967,CC(C)(C)[Si](C)(C)OCC[C@@H]1CNC(c2ccc(Cl)c(Cl)c2)O1.COc1ccc(S(=O)(=O)Cl)cc1OC>>COc1ccc(S(=O)(=O)N2C[C@@H](CCO[Si](C)(C)C(C)(C)C)OC2c2ccc(Cl)c(Cl)c2)cc1OC,,c1ccncc1,,Cl,,test
US20160169835A1,OB(O)c1ccc(S)cc1.[Au]>>OB(O)c1ccccc1.[Au],,CCO,,,,test
US20090221663A1,CCOC(=O)c1cnn(-c2ccc(Cl)c(C(F)(F)F)c2)c1C(C)(C)C>>CC(C)(C)c1c(C(=O)O)cnn1-c1ccc(Cl)c(C(F)(F)F)c1,,CO,,[Na+].[OH-],,test
US20150218183A1,C[Si](C)(C)CCOCn1c(O[C@@H]2CO[C@H]3[C@@H]2OC[C@H]3O)nc2cc(-c3ccc(-c4ccc(-n5cncn5)cc4)cc3)c(Cl)cc21>>O[C@@H]1CO[C@@H]2[C@H](Oc3nc4cc(-c5ccc(-c6ccc(-n7cncn7)cc6)cc5)c(Cl)cc4[nH]3)CO[C@@H]21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040259884A1,CCN(C(C)C)C(C)C.CCOc1cc(C(F)(F)F)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1.CN(C)C(=O)CCl.CN(C)C=O>>CCOc1cc(C(F)(F)F)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)NC)CC1,,ClCCl,O,,,test
US20160009703A1,ClCCCBr.On1nnc2ccccc21.c1c[nH]cn1>>ClCCCOn1cnc2ccccc21,,CN1CCCC1=O,,O,[H-].[Na+],test
US20060020003A1,CCCCc1oc2ccccc2c1C(=O)N(C)Cc1ccc(-c2ccc(OC(Cc3ccccc3)C(=O)OC)c(Br)c2)cc1>>CCCCc1oc2ccccc2c1C(=O)N(C)Cc1ccc(-c2ccc(OC(Cc3ccccc3)C(=O)O)c(Br)c2)cc1,,CO,,O,[Na+].[OH-],test
US20040044203A1,CC[Si](Cl)(CC)CC.O=[N+]([O-])CC(O)c1cccc(Cl)c1>>CC[Si](CC)(CC)OC(C[N+](=O)[O-])c1cccc(Cl)c1,,CN(C)C=O,,c1c[nH]cn1,,test
US20160257652A1,CC(C)(C)[Si](C)(C)OC1CC(=O)C1>>CC(C)(C)[Si](C)(C)O[C@@H]1C[C@H](O)C1,,CO,,Cl,[BH4-].[Na+],test
US20060079696A1,BrCc1ccccc1.Cc1cc(C=O)cc(C)c1O>>Cc1cc(C=O)cc(C)c1OCc1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130158003A1,Cc1ccc2c(NCc3ccccc3)nccc2n1>>Cc1ccc2c(N)nccc2n1,,O,O=S(=O)(O)O,[Na+].[OH-],,test
US20020091264A1,CC(O)c1cccc(N(C)C(=O)OC(C)(C)C)n1.CCOC(=O)CC1Cc2ccc(O)cc2Oc2ccccc21>>CNc1cccc(CCOc2ccc3c(c2)Oc2ccccc2C(CC(=O)O)C3)n1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04415570,C1CCNC1.Nc1nc(Cl)nc(-c2ccc(Cl)cc2)n1>>Nc1nc(-c2ccc(Cl)cc2)nc(N2CCCC2)n1,,C1COCCO1,,,,test
US20150094297A1,COc1cc(OCc2csc(C3(O)CCC(C(=O)OC(C)(C)C)CC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1>>COc1cc(OCc2csc(C3(O)CCC(C(=O)O)CC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1,,Cc1ccccc1,ClCCl,CO,O=C(O)C(F)(F)F,test
US05221685,N=C1NC(C(F)(F)F)(C(F)(F)F)C(=C(F)C(F)(F)F)S1.O=C=NC(=O)c1ccccc1Cl>>O=C(NC(=O)c1ccccc1Cl)NC1=NC(C(F)(F)F)(C(F)(F)F)C(=C(F)C(F)(F)F)S1,,Cc1ccccc1,,,,test
US20130345123A1,CC(C)(C)OC(=O)N[C@H]1CCS[C@H]2CCC[C@@H](C(=O)O)N2C1=O.NN>>CC(C)(C)OC(=O)N[C@H]1CCS[C@H]2CCC[C@@H](C(=O)NN)N2C1=O,,CCOC(C)=O,ClCCl,CC(C)COC(=O)Cl,CN1CCOCC1,test
US06008229,CC(=O)OC(C)=O.Cc1cn2cccc(O)c2n1>>CC(=O)Oc1cccn2cc(C)nc12,,ClCCl,,c1ccncc1,,test
US20140088167A1,CCn1c(C(=O)NC(c2cccc(C(F)(F)F)c2)C(F)(F)F)cc2cc(CNC(=O)OC(C)(C)C)c(Cl)cc21.O=C(O)C(F)(F)F>>CCn1c(C(=O)NC(c2cccc(C(F)(F)F)c2)C(F)(F)F)cc2cc(C[NH3+])c(Cl)cc21.O=C([O-])C(F)(F)F,,ClCCl,,,,test
US20140315886A1,CNc1nc(-c2cccnc2)nc2c(OC)cc(Br)cc12.OB(O)c1ccc(F)c2ccoc12>>CNc1nc(-c2cccnc2)nc2c(OC)cc(-c3ccc(F)c4ccoc34)cc12,,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20040167160A1,COP(=O)(OC)C(NC(C)=O)C(C)=O.O=Cc1ccsc1C=O>>CC(=O)c1cc2ccsc2cn1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20080275064A1,CC(=O)CC(C)=O.NN.Nc1cc(Cl)nc(-c2ccco2)n1>>Cc1cc(C)n(-c2cc(N)nc(-c3ccco3)n2)n1,,CCO,,,,test
US20050176724A1,CC(C)(C)OC(=O)N1CCC(=Cc2cccc(C#N)c2)CC1.Cl>>Cl.N#Cc1cccc(C=C2CCNCC2)c1,,CCOCC,,CO,,test
US06232338B1,C=CCOC(=O)N1C[C@@H](SC(=O)OC(C)(C)C)C[C@H]1C=O.NCCc1cccc2ccccc12>>C=CCOC(=O)N1C[C@@H](SC(=O)OC(C)(C)C)C[C@H]1CNCCc1cccc2ccccc12,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20160046635A1,CCCNc1nc(NC)c2nc(NCC(=O)OC(C)(C)C)nc(NC)c2n1>>CCCNc1nc(NC)c2nc(NCC(=O)O)nc(NC)c2n1,,C1COCCO1,,Cl,[Na+].[OH-],test
US06268535B1,CN(C)[C@@H]1C[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc21.O=C(O)/C=C\C(=O)O>>O=C([O-])/C=C\C(=O)O.[NH4+],,CCO,,,,test
US05665718,CCCNCCC.O=C1c2c(Cl)cccc2-n2cnc(-c3nnc(CCl)o3)c2[C@@H]2CCCN12>>CCCN(CCC)Cc1nnc(-c2ncn3c2[C@@H]2CCCN2C(=O)c2c(Cl)cccc2-3)o1,,CN(C)C=O,,,,test
US20100216788A1,O=[N+]([O-])c1cnc(Cl)c(Cl)c1.Oc1cccc(C(F)(F)F)c1>>O=[N+]([O-])c1cnc(Oc2cccc(C(F)(F)F)c2)c(Cl)c1,,C1CCOC1,,O,[H-].[Na+],test
US20090233919A1,CC1(C)CN(Cc2ccccc2)CC(C)(C)O1>>CC1(C)CNCC(C)(C)O1,[Pd],CCO,,,,test
US06005102,CCN(C(C)C)C(C)C.Cc1ccccc1>>c1ccc2[nH]ccc2c1,,CO,,O,,test
US05039672,COC(=O)C1(CO)CCOc2ccc(F)cc21>>O=C(O)C1(CO)CCOc2ccc(F)cc21,,CCOCC,ClCCl,[Na+].[OH-],,test
US20140162971A1,CCS(=O)(=O)c1ccc(OCC2CC2(F)F)c(-c2cn(C)c(=O)c3[nH]c(C(=O)O)cc23)c1.NCC(F)(F)F>>CCS(=O)(=O)c1ccc(OCC2CC2(F)F)c(-c2cn(C)c(=O)c3[nH]c(C(=O)NCC(F)(F)F)cc23)c1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20110009454A1,NCc1ccc(Oc2ccccc2)o1.Nc1ncccc1C(=O)O>>Nc1ncccc1C(=O)NCc1ccc(Oc2ccccc2)o1,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20150266867A1,Cc1nn(C[C@@H]2[C@H](NC(=O)/C(=N\OC3(C(=O)OC(c4ccccc4)c4ccccc4)CC3)c3csc(NC(=O)OC(C)(C)C)n3)C(=O)N2S(=O)(=O)O)nc1CNC(=O)OC(C)(C)C>>Cc1nn(C[C@@H]2[C@H](NC(=O)/C(=N\OC3(C(=O)O)CC3)c3csc(N)n3)C(=O)N2S(=O)(=O)O)nc1CN,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US05169858,CC(C)(S)[C@H](N)C(=O)O.O=Cc1ccccc1>>CC1(C)SC(c2ccccc2)NC1C(=O)O,,CCO,O,,,test
US20020156081A1,O=C(CNc1ccc(Br)cc1)c1ccccc1>>OC(CNc1ccc(Br)cc1)c1ccccc1,,CO,,[BH4-].[Na+],,test
US20140315949A1,CCOC(C)c1ccc(C(=O)OC)cc1>>CCOC(C)c1ccc(C(=O)O)cc1,,CO,O,Cl,[Li+].[OH-],test
US05334740,CC(=O)Cl.CC(C)(C)[Si](C)(C)OC1CC2=NOCC2C(O[Si](C)(C)C(C)(C)C)C1O>>CC(=O)OC1C(O[Si](C)(C)C(C)(C)C)CC2=NOCC2C1O[Si](C)(C)C(C)(C)C,CN(C)c1ccncc1,CCOCC,ClCCl,CCN(CC)CC,,test
US06107329,CO.NC(Cc1ccc(C2=NCCN2)cc1)C(=O)O>>COC(=O)C(N)Cc1ccc(C2=NCCN2)cc1,,O=S(Cl)Cl,,Cl,Cl,test
US06399629B1,CC(C)(C)OC(=O)N1C[C@H](Oc2cccc(-c3ccccc3)c2)C[C@H]1C=O.C[N+](=O)[O-]>>CC(C)(C)OC(=O)N1C[C@H](Oc2cccc(-c3ccccc3)c2)C[C@H]1C(O)C[N+](=O)[O-],,C1CCOC1,,CN(C)C(=N)N(C)C,,test
US20030125346A1,N#CCC(=O)C1CCCCC1.NO>>Nc1cc(C2CCCCC2)no1,,CCO,,,,test
US20160031830A1,COCCOC.N#Cc1ccc(C2NC(=O)N(c3cccc(C(F)(F)F)c3)C3=C2C(=O)CC3)c(Br)c1.OB(O)c1cncnc1>>CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1-c1cncnc1,,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US05985873,CC1CCC(c2cccc(NC(=O)N3CCC(=O)CC3)c2)(N2CCN(c3ccccc3)CC2)CC1>>CC1CCC(c2cccc(NC(=O)N3CCC(O)CC3)c2)(N2CCN(c3ccccc3)CC2)CC1,,CCO,,[BH4-].[Na+],,test
US20070066624A1,COC(=O)c1ccc(Sc2ccc(CBr)cn2)cc1.O=C1N(C2CCOCC2)C[C@@H](c2cccc(F)c2)N1C1CCNCC1>>COC(=O)c1ccc(Sc2ccc(CN3CCC(N4C(=O)N(C5CCOCC5)C[C@H]4c4cccc(F)c4)CC3)cn2)cc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US04727073,CC(=O)c1c(C)nc(-c2ccccc2)nc1-c1cccc([N+](=O)[O-])c1>>Cc1nc(-c2ccccc2)nc(-c2cccc([N+](=O)[O-])c2)c1C(C)O,,CO,,[BH4-].[Na+],,test
US20110245241A1,Cn1c(C2CCCC2)nc(-c2nc(Cc3ccc(F)cc3)no2)c(OCc2ccccc2)c1=O>>Cn1c(C2CCCC2)nc(-c2nc(Cc3ccc(F)cc3)no2)c(O)c1=O,,O=C(O)C(F)(F)F,,,,test
US04772600,NCCN1CCCCC1.O=C(O)Cn1c(-c2cccc(Cl)c2)nc2cccnc21>>O=C(Cn1c(-c2cccc(Cl)c2)nc2cccnc21)NCCN1CCCCC1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US05489602,CC(=O)NC(Cc1ccccc1)C(C)=O.Cl>>CC(=O)C(N)Cc1ccccc1.Cl,,CCO,,,,test
US20110152235A1,C1CCNCC1.O=C1NC(=O)/C(=C/c2cccc(Br)n2)S1>>O=C1NC(=O)/C(=C/c2cccc(N3CCCCC3)n2)S1,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US20100113502A1,CCCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CNCC2.O=C(O)C(F)(F)F.O=C1CCOCC1>>CCCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCOCC1)CC2.O=C(O)C(F)(F)F,,ClCCl,,[Na+].[OH-],,test
US04645771,CC(=O)OC(C)=O.Cl.Oc1ccc(CN2CC=CCC2)cc1>>CC(=O)Oc1ccc(CN2CC=CCC2)cc1.Cl,,c1ccncc1,,,,test
US04975462,CNC(=O)CC#N.O=C=Nc1ccc(C(F)(F)F)cc1>>CNC(=O)C(C#N)C(=O)Nc1ccc(C(F)(F)F)cc1,,C1CCOC1,CCCCCC,[H-].[Na+],,test
US04971982,CC(C)=CC(O)(c1ccccn1)c1ccccc1O>>CC1(C)C=C(c2ccccn2)c2ccccc2O1,,COCCOCCOC,,,,test
US20060264429A1,Cc1ccc2c(N3CCNCC3)cccc2n1.O=C1COc2ccc(C(=O)CCl)cc2N1>>Cc1ccc2c(N3CCN(CC(=O)c4ccc5c(c4)NC(=O)CO5)CC3)cccc2n1.Cl,,CC#N,,CCN(C(C)C)C(C)C,,test
US20100323994A1,Nc1ccon1.O=C(Nc1ccncc1F)c1cnc2c(Br)cc(Cl)nn12>>O=C(Nc1ccncc1F)c1cnc2c(Nc3ccon3)cc(Cl)nn12,,C1CCOC1,,CN(C)C=O,[H-].[Na+],test
US20130245064A1,O=C(O)c1ccc(-c2nc3cc(Cl)c(Cl)cc3[nH]2)cc1.O=S(Cl)Cl>>O=C(Cl)c1ccc(-c2nc3cc(Cl)c(Cl)cc3[nH]2)cc1,CN(C)C=O,,,,,test
US06080752,CS(=O)(=O)Cl.ClCCl.O=C(NCCCCN1CCC[C@H]2c3cccc(O)c3CC[C@@H]21)c1ccc(-c2ccccc2)cc1>>CS(=O)(=O)Oc1cccc2c1CC[C@H]1[C@H]2CCCN1CCCCNC(=O)c1ccc(-c2ccccc2)cc1.Cl,,ClCCl,,CCN(CC)CC,O=C([O-])[O-].[K+].[K+],test
US04535088,C#CCN(C)c1ncc(C)s1.II>>Cc1cnc(N(C)CC#CI)s1,,C1CCOC1,ClC(Cl)Cl,CCCCCC,[Li]CCCC,test
US20010003744A1,CC(=O)OC[C@@H]1O[C@H](n2c(Br)nc3cc(Cl)c(Cl)cc32)[C@@H](OC(C)=O)[C@H]1OC(C)=O.Nc1ccccc1>>OC[C@@H]1O[C@H](n2c(Nc3ccccc3)nc3cc(Cl)c(Cl)cc32)[C@@H](O)[C@H]1O,,ClCCl,,CCO,,test
US06608070B1,CON(C)C(=O)c1snnc1C.C[Mg]I>>CC(=O)c1snnc1C,,C1CCOC1,,CCOCC,,test
US20100197630A1,OC1COc2ccccc2OC1>>O=C1COc2ccccc2OC1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20140018319A1,O=S(=O)(CC1(N2CCN(C(c3ccccc3)c3ccccc3)CC2)COC1)c1ccccc1>>CC1(N2CCN(C(c3ccccc3)c3ccccc3)CC2)COC1,,C1CCOC1,CO,Cl,[Mg],test
US20140343032A1,CC(C)(C)OC(=O)N1C2COCC1C(F)c1oncc12>>FC1c2oncc2C2COCC1N2,,ClCCl,O=C(O)C(F)(F)F,,,test
US20090306076A1,COC(=O)c1nccnc1OC>>COc1nccnc1C=O,,Cc1ccccc1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20060241142A1,CC(=O)Cl.N#CC1(c2ccc(Cl)c(Cl)c2)CCNCC1>>CC(=O)N1CCC(C#N)(c2ccc(Cl)c(Cl)c2)CC1,,ClCCl,,,,test
US20090181928A1,O=C1Nc2ccccc2CCC1Br.O=[N+]([O-])c1ccc(O)cc1OCc1ccccc1>>O=C1Nc2ccccc2CCC1Oc1ccc([N+](=O)[O-])c(OCc2ccccc2)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110274654A1,C#Cc1ccccc1Cl.Cc1ccc(S(=O)(=O)N=[N+]=[N-])cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3ccccc3Cl)nn2)cc1,[Cu]I,ClC(Cl)Cl,,Cc1cccc(C)n1,,test
US20050245563A1,CCOC(=O)CC(C)NC(=O)OC(C)(C)C>>CC(CCO)NC(=O)OC(C)(C)C,,C1CCOC1,,O,O=C([O-])[O-].[K+].[K+],test
US20030199522A1,CC(C)(C)OC(=O)CBr.CN(C)CCO>>CN(C)CCOCC(=O)OC(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20030207926A1,COC(=O)Cc1ccc(O)c(N)c1.O=C(Cl)C(F)(F)C(F)(F)C(F)(F)F>>COC(=O)Cc1ccc(O)c(NC(=O)C(F)(F)C(F)(F)C(F)(F)F)c1,,COCCOC,,O=C([O-])O.[Na+],,test
US20040029928A1,COc1ccc(S(=O)(=O)Cl)cc1.Nc1ccc([N+](=O)[O-])cc1C(=O)c1ccccc1>>COc1ccc(S(=O)(=O)Nc2ccc([N+](=O)[O-])cc2C(=O)c2ccccc2)cc1,,CCOC(C)=O,,Cl,c1ccncc1,test
US05298652,CCCCCCCCCCCCCCCCCCBr.COC(=O)c1cc(O)cc([N+](=O)[O-])c1>>CCCCCCCCCCCCCCCCCCOc1cc(C(=O)OC)cc([N+](=O)[O-])c1,,CN(C)C=O,,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20060235024A1,CC(C)OC(=O)Cl.CCC(C#Cc1cccc(Cl)c1)N1CCNCC1>>CCC(C#Cc1cccc(Cl)c1)N1CCN(C(=O)OC(C)C)CC1,,ClCCl,,CCN(CC)CC,,test
US20100069367A1,CCOC(=O)c1cn(-c2ccc(-c3cccc(S(C)(=O)=O)c3)cc2)c(-c2ccccc2C(F)(F)F)n1.N>>CS(=O)(=O)c1cccc(-c2ccc(-n3cc(C(N)=O)nc3-c3ccccc3C(F)(F)F)cc2)c1,,CO,,[C-]#N.[Na+],,test
US04886817,NCCNCc1cccnc1.O=C(n1ccnc1)n1ccnc1>>O=C1NCCN1Cc1cccnc1,,C1CCOC1,,,,test
US04330321,CC(Oc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1)C(N)=O.CCCCN=C=O>>CCCCNC(=O)NC(=O)C(C)Oc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1,,Cc1ccccc1,,,,test
US04419517,COc1cccc([C@@]23CCCC[C@H]2CN(C)CC3)c1>>C1CC[C@H]2CCNC[C@@H]2C1,,ClCCl,,BrB(Br)Br,CO,test
US08912186B2,O=C(CBr)c1ccccc1.Oc1ccc(Cl)cc1>>O=C(COc1ccc(Cl)cc1)c1ccccc1,,CN(C)C=O,,O,,test
US20110152296A1,ON=Cc1c(Cl)ncnc1Cl>>N#Cc1c(Cl)ncnc1Cl,,ClC(Cl)Cl,,O=S(Cl)Cl,,test
US20130072677A1,CCOC(=O)C(NC(=O)c1ccc(I)cc1)C(=O)OCC.CN>>CNC(=O)C(NC(=O)c1ccc(I)cc1)C(=O)OC,,CO,,,,test
US20120277100A1,CN(C)C=O.ClCCl.O=C(Cl)C(=O)Cl.O=C(O)C(C(=O)O)c1ccccc1F.Oc1c(Cl)cc(Cl)cc1Cl>>O=C(Oc1c(Cl)cc(Cl)cc1Cl)C(C(=O)Oc1c(Cl)cc(Cl)cc1Cl)c1ccccc1F,CN(C)C=O,ClCCl,,,,test
US20150011548A1,CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cn(C)nn4)ccc32)c1>>Cn1cc(-c2ccc3c(c2)ncn3-c2cc(N)cc(-c3ccc(F)cc3F)c2)nn1,,CCO,,[Na+].[OH-],,test
US20090209607A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCC(O)Cc1ccccc1>>CN(CC(O)Cc1ccccc1)C(=O)OC(C)(C)C,,C1CCOC1,,,,test
US05604253,C[Mg]Cl.N#CCC1(CC=O)CC1>>CC(O)CC1(CC#N)CC1,,C1CCOC1,,,,test
US20080312270A1,COC(=O)Cc1ccc(Oc2ccc3[nH]c(C)cc3c2NS(=O)(=O)c2ccc(Cl)cc2Cl)c(OC)c1>>COc1cc(CC(=O)O)ccc1Oc1ccc2[nH]c(C)cc2c1NS(=O)(=O)c1ccc(Cl)cc1Cl,,CO,O,Cl,[Li+].[OH-],test
US20120149691A1,CCOC(=O)c1ccc(C(=O)OCC)n1N.CCOC(CC#N)OCC>>CCOC(=O)c1ccc2c(O)c(C#N)cnn12,,CCO,CCOC(C)=O,C1CCC2=NCCCN2CC1,Cl,test
US20070275907A1,CCc1ccc(Cc2cc3c(cc2Cl)CO[C@]32O[C@H](CN=[N+]=[N-])[C@@H](O)[C@H](O)[C@H]2O)cc1>>CCc1ccc(Cc2cc3c(cc2Cl)CO[C@]32O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)cc1,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20160243100A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CC(C)(S(=O)(=O)c1cccc(F)c1)S(=O)(=O)c1cccc(F)c1>>CC(C)(C)OC(=O)N1CCC(O)(C(C)(C)S(=O)(=O)c2cccc(F)c2)CC1,,C1CCOC1,,,,test
US03971784,CS(=O)(=O)Cl.O=c1[nH]cc(F)c(=O)[nH]1>>CS(=O)(=O)n1cc(F)c(=O)[nH]c1=O,,CO,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20060025601A1,CCNC(=O)[O-].COc1cc2c(cc1Cl)C(C)C1CNCC21>>CC1c2cc(Cl)c(O)cc2C2CNCC12.CCNC(=O)[O-],,ClCCl,,BrB(Br)Br,,test
US20140107126A1,CC(=O)Nc1ncsc1Br.CCCc1nc(C)c[nH]1>>CCCc1nc(C)cn1-c1scnc1NC(C)=O,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US07067179B1,CCC(=O)c1ccc2c(c1F)Cc1c(F)cccc1-2>>CC=Cc1ccc2c(c1F)Cc1c(F)cccc1-2,,CO,,Cl,[BH4-].[Na+],test
US20060211720A1,CCOc1ccc(F)c(C=O)c1.N#Cc1ccc(N)cc1>>CCOc1ccc(F)c(/C=N/c2ccc(C#N)cc2)c1,,Cc1ccccc1,,,,test
US20120053166A1,CC(=O)Cl.Cc1ccc(S(=O)(=O)n2ncc3c(-c4nnn[nH]4)cc(-c4cnc(Cl)c(NS(C)(=O)=O)c4)cc32)cc1>>Cc1ccc(S(=O)(=O)n2ncc3c(-c4nnc(C)o4)cc(-c4cnc(Cl)c(NS(C)(=O)=O)c4)cc32)cc1,,Cc1ccccc1,,,,test
US20110135670A1,CCC[C@H](C)Oc1nc2nc(OC)nc-2c(N)[nH]1.ClCCCCBr>>CCC[C@H](C)Oc1nc(N)c2nc(OC)n(CCCCCl)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030092720A1,COc1ccc(Cn2nnnc2-c2c(O)nc3cc(CCc4nc(C(C)C)cs4)ccn3c2=O)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc(Cn2nnnc2-c2c(OS(=O)(=O)c3ccc(C)cc3)nc3cc(CCc4nc(C(C)C)cs4)ccn3c2=O)cc1,,ClCCl,,CCN(CC)CC,CN(C)c1ccccn1,test
US05840732,Cl.O=c1c(-c2ccccc2)c2n(c(=O)n1CCCCSc1cccc3nccn13)CCCS2=O>>Cl.O=c1c(-c2ccccc2)c2n(c(=O)n1CCCCSc1cccc3nccn13)CCCS2=O,,CO,,,,test
US20110009454A1,N#Cc1cccc(F)c1.Oc1cccc(I)c1>>N#Cc1cccc(Oc2cccc(I)c2)c1,,O,,CN(C)C=O,,test
US20140094462A1,CC(C)(C)OC(=O)N[C@@H]1CC=CCCCOC(=O)[C@@H]2CCCN2C1=O>>N[C@@H]1CC=CCCCOC(=O)[C@@H]2CCCN2C1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020198200A1,Nc1nccs1.O=C(O)C(OC1CCCC1)c1ccc(Cl)c(Cl)c1>>O=C(Nc1nccs1)C(OC1CCCC1)c1ccc(Cl)c(Cl)c1,,ClCCl,O,CCN(C(C)C)C(C)C,,test
US20050267095A1,COC(=O)C1CC(C#N)(c2ccc(OCCCN3CCCC3)cc2)CCC1=O>>N#CC1(c2ccc(OCCCN3CCCC3)cc2)CCC(=O)CC1,,O,,CS(C)=O,[Cl-].[Na+],test
US20100261755A1,COC(=O)c1ccnc(Cl)c1.Cc1cc(B2OC(C)(C)C(C)(C)O2)ccc1C(F)(F)F>>COC(=O)c1ccnc(-c2ccc(C(F)(F)F)c(C)c2)c1,Cl[Pd]Cl,CO,,O=C([O-])[O-].[K+].[K+],,test
US20030166658A1,Cn1c(NN)nc2ccccc21.O=C(c1ccccn1)C1CC1>>Cn1c(N/N=C(\c2ccccn2)C2CC2)nc2ccccc21,CC(=O)O,CO,,,,test
US20030018032A1,CC=O.Nc1ccccn1.[C-]#[N+]C(C)(C)C>>Cc1nc2ccccn2c1NC(C)(C)C,,[O-][Cl+3]([O-])([O-])O,,,,test
US20080103123A1,CC(C)(C)OC(=O)N1CCN(C(=O)Cc2ccc(-c3ccc(S(C)(=O)=O)cc3)nc2)CC1>>CC(C)(C)OC(=O)N1CCN(CCc2ccc(-c3ccc(S(C)(=O)=O)cc3)nc2)CC1,,C1CCOC1,,,,test
US20110021522A1,COc1ccc(B(O)O)cc1OC.Nc1cccc(Br)c1>>COc1ccc(-c2cccc(N)c2)cc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20100273770A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c3OCCN(C(=O)OC(C)(C)C)C4CCCC(=O)O)no2)cc1Cl.Cl>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3OCCNC4CCCC(=O)O)no2)cc1Cl.Cl,,C1COCCO1,,,,test
US20100298566A1,Br.Cc1nc2n(c(=O)c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCCC2O>>Br.Cc1nc2n(c(=O)c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCCC2O,,CO,,,,test
US08906135B1,CI.c1ccc(-c2cn(-c3ccncc3)nn2)cc1>>C[n+]1nn(-c2ccncc2)cc1-c1ccccc1.[I-],,CC#N,,,,test
US20050014749A1,Cc1ccc(S(=O)(=O)N2CCNC(=O)CC2CC(=O)O)cc1.N[C@@H]1CCCc2cc(CN3CCCCC3)ccc21>>Cc1ccc(S(=O)(=O)N2CCNC(=O)CC2CC(=O)N[C@@H]2CCCc3cc(CN4CCCCC4)ccc32)cc1,,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20130225524A1,CCOC(=O)c1cnc2cc(Cl)c(OC)cc2c1O>>COc1cc2c(O)c(C(=O)O)cnc2cc1Cl,,CCO,,[Na+].[OH-],,test
US20020161262A1,BrCCc1ccccc1.COc1cccc(C=O)c1>>COc1cccc(C(O)CCc2ccccc2)c1,,CCOCC,,[Mg],[Cl-].[NH4+],test
US20050075342A1,CC(=O)C(C(=O)OC(C)(C)C)C(=O)c1cccc(Cl)c1>>CC(=O)CC(=O)c1cccc(Cl)c1,,O=C(O)C(F)(F)F,,,,test
US05159105,O=S(=O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)S(F)(F)(F)(F)F.[Li]O>>[Li]OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)S(F)(F)(F)(F)F,,CO,,O,,test
US20080039459A1,C=O.COC1(c2cc3nc(Cl)nc(N4CCOCC4)c3s2)CCNCC1>>COC1(c2cc3ncnc(N4CCOCC4)c3s2)CCN(C)CC1,,CO,,[BH4-].[Na+],,test
US20020042396A1,CC(C)(C)OC(=O)N1CC[C@H]1C(=O)O.O=C1CCC(=O)N1O>>CC(C)(C)OC(=O)N1CC[C@H]1C(=O)ON1C(=O)CCC1=O,,C1CCOC1,,ClCCCl,,test
US20160024021A1,COC(=O)c1cc(/C=C/c2cnc(N)nc2)c(F)c(OC)c1>>COC(=O)c1cc(CCc2cnc(N)nc2)c(F)c(OC)c1,[Pd],C1CCOC1,,,,test
US20150322056A1,CC(C)(C)OC(=O)[C@H](O)[C@H]1OCCN(c2cccc(C(F)(F)F)n2)C1=O.CI>>CC(C)(C)OC(=O)[C@H](O)[C@@]1(C)OCCN(c2cccc(C(F)(F)F)n2)C1=O,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20160145247A1,C1COCCN1.CC(C)(C)OC(=O)Cc1ccccc1OCc1cc(Br)cc(CO)c1>>CC(C)(C)OC(=O)Cc1ccccc1OCc1cc(Br)cc(CN2CCOCC2)c1,,C1CCOC1,,CS(=O)(=O)Cl,,test
US05977025,CC1=C(c2ccccc2)C(=O)N(C(C)(C)C(=O)O)CO1.Oc1cc(Cl)cc(Cl)c1>>CC1=C(c2ccccc2)C(=O)N(C(C)(C)C(=O)Oc2cc(Cl)cc(Cl)c2)CO1,,ClC(Cl)(Cl)Cl,ClCCl,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080269291A1,CCS(=O)(=O)N1CCC(c2cn(C(=O)OC(C)(C)C)c3c(C(=O)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc(B4OC(C)(C)C(C)(C)O4)cc23)CC1.OO>>CCS(=O)(=O)N1CCC(c2cn(C(=O)OC(C)(C)C)c3c(C(=O)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc(O)cc23)CC1,,COCCOC,,[Na+].[OH-],,test
US20110053782A1,CC#Cc1cc(C=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)c1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CC#Cc1cc(C=O)n([C@H]2C[C@H](O)[C@@H](COC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c1,,c1ccncc1,,CC(C)NC(C)C,,test
US05034417,CS(=O)(=O)Cl.Cc1cc(N)c(Sc2ccc(F)cc2F)cc1C#N>>Cc1cc(NS(C)(=O)=O)c(Sc2ccc(F)cc2F)cc1C#N,,c1ccncc1,,CCN(CC)CC,,test
US20110028445A1,OC1CCC2CC1CCN2Cc1ccccc1>>O=C1CCC2CC1CCN2Cc1ccccc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20130225554A1,CC(C)(C)OC(=O)N=C(NC(=O)OC(C)(C)C)N1CCC(ONC(=O)[C@@H]2CC[C@@H]3CN2C(=O)N3OCc2ccccc2)CC1>>CC(C)(C)OC(=O)N=C(NC(=O)OC(C)(C)C)N1CCC(ONC(=O)[C@@H]2CC[C@@H]3CN2C(=O)N3O)CC1,[Pd],CO,,,,test
US20150057238A1,COC(=O)C1C(C)C1C(=O)c1ccc(Cl)c(Cl)c1>>CC1C(C(=O)O)C1C(=O)c1ccc(Cl)c(Cl)c1,,C1CCOC1,,[Na+].[OH-],,test
US20060154931A1,CNOC.O=C(O)c1ccc(OCc2ccc3ccccc3n2)cc1>>CON(C)C(=O)c1ccc(OCc2ccc3ccccc3n2)cc1,,O=S(Cl)Cl,,CCN(CC)CC,Cl,test
US05399703,CCCCCCOc1ccc(C(=O)Cl)cc1.N#Cc1ccccc1Oc1ccccc1N>>CCCCCCOc1ccc(C(=O)Nc2ccccc2Oc2ccccc2C#N)cc1,,CCOCC,,CCN(CC)CC,,test
US20120122848A1,CCC=O.COc1cc2c(cc1N(C)C(=O)OC(C)(C)C)C[C@@H]1[C@@H]3CCCC[C@]23CCN1C(=O)OCc1ccccc1>>CCCN(C)c1cc2c(cc1OC)[C@@]13CCCC[C@H]1[C@@H](C2)N(C(=O)OCc1ccccc1)CC3,,ClCCCl,ClCCl,O=C(O)C(F)(F)F,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20030232848A1,Cc1ccc(-c2c(OCCO)nn(C)c2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)cc1.O=C(O)c1ccccn1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cc1ccc(-c2c(OCCOC(=O)Nc3ccccn3)nn(C)c2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)cc1,CN(C)c1ccncc1,Cc1ccccc1,,CCN(CC)CC,,test
US20040132726A1,C1CNCCN1.ClCc1noc(-c2cccc(Cl)c2)n1>>Clc1cccc(-c2nc(CN3CCNCC3)no2)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04178380,C=CCN.COC(=O)C1COc2ccc(Cl)cc2C1>>C=CCNC(=O)C1COc2ccc(Cl)cc2C1,,CCO,ClCCl,,,test
US20110152285A1,BrCc1ccccc1.O=[N+]([O-])c1ccc(N2CCNCC2)cc1>>O=[N+]([O-])c1ccc(N2CCN(Cc3ccccc3)CC2)cc1,,CC#N,,CCN(CC)CC,,test
US08394858B2,CC(C)(C)OC(=O)N[C@H](CCO)c1ccccc1.CI>>COCC[C@@H](NC(=O)OC(C)(C)C)c1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20140005213A1,CO[C@@H](C)CO.Cc1ccccc1S(=O)(=O)Cl>>CO[C@@H](C)COS(=O)(=O)c1ccc(C)cc1,,ClCCl,,CCN(CC)CC,,test
US20100144710A1,CCCCBr.COC(=O)Cc1ccc(O)cc1>>CCCCOc1ccc(CC(=O)OC)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20120329649A1,CCOC(=O)c1cc(/C=C/C(c2cc(Cl)cc(Cl)c2)C(F)(F)F)ccc1-n1cncn1>>O=C(O)c1cc(/C=C/C(c2cc(Cl)cc(Cl)c2)C(F)(F)F)ccc1-n1cncn1,,Cl,,,,test
US20070155839A1,OB(O)c1ccoc1.Oc1ccc(C(=C2CCCCCCC2)c2ccc(Br)cc2)cc1>>Oc1ccc(C(=C2CCCCCCC2)c2ccc(-c3ccoc3)cc2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150218144A1,Cl.O=C=Nc1ccc(Cl)cc1.O[C@@H](CN1CCOC(c2ccc(C(F)(F)F)cc2)C1)C(F)(F)F>>Cl.O=C(Nc1ccc(Cl)cc1)O[C@@H](CN1CCO[C@H](c2ccc(C(F)(F)F)cc2)C1)C(F)(F)F,,CC#N,,,,test
US20090076046A1,CC(C)(C)OC(=O)Nc1nc(Cl)c(C(O)c2cn(S(=O)(=O)c3ccccc3)c3ncc(Cl)cc23)s1>>CC(C)(C)OC(=O)Nc1nc(Cl)c(Cc2cn(S(=O)(=O)c3ccccc3)c3ncc(Cl)cc23)s1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20100152166A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1ccc([C@@H]2CC[C@@H](OCc3c(-c4c(Cl)cccc4Cl)noc3C3CC3)CC2)cc1>>O=S(=O)(Oc1ccc([C@@H]2CC[C@@H](OCc3c(-c4c(Cl)cccc4Cl)noc3C3CC3)CC2)cc1)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US20040122244A1,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)O)c2)=C(C)C1=O.Nc1ccc(N2CCOCC2)nc1>>COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)Nc3ccc(N4CCOCC4)nc3)c2)=C(C)C1=O,,ClCCl,,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US20050272672A1,Brc1cccnc1.COc1cccc(B(O)O)c1>>Oc1cccc(-c2cccnc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20050143452A1,Cc1ccc(S(=O)(=O)OCC2Cc3ccc(O)cc3O2)cc1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1ccc(S(=O)(=O)OCC2Cc3ccc(OS(=O)(=O)C(F)(F)F)cc3O2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040152894A1,CC(C)Oc1nc(O)cc(C(F)(F)F)n1.COC=C(C(=O)OC)c1ccccc1CCl>>COC=C(C(=O)OC)c1ccccc1COc1cc(C(F)(F)F)nc(OC(C)C)n1,,CN(C)C=O,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US05866566,CCOC(=O)Cl.NC(=O)N1c2ccccc2CC(=NO)c2ccccc21>>CCOC(=O)ON=C1Cc2ccccc2N(C(N)=O)c2ccccc21,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US04681886,CCOC(=O)CCN(CC)C(=O)N1C[C@@H](Oc2cccc(C3NC(=O)c4cc(S(N)(=O)=O)c(Cl)cc4N3)c2)C[C@H]1C(=O)OCc1ccccc1>>CCOC(=O)CCN(CC)C(=O)N1C[C@@H](Oc2cccc(C3NC(=O)c4cc(S(N)(=O)=O)c(Cl)cc4N3)c2)C[C@H]1C(=O)O,[Pd],CCO,,,,test
US06291475B1,CC(C)(C)OC(=O)N1CC2CNCC(C2)C1.N#Cc1ccc(OCCBr)cc1>>CC(C)(C)OC(=O)N1CC2CC(CN(CCOc3ccc(C#N)cc3)C2)C1,,CC#N,,,,test
US20050148624A1,CCC(=O)c1c(-c2ccc(C(=O)OC)cc2)c2cc(Cl)ccc2c(=O)n1Cc1ccc(S(C)(=O)=O)cc1>>CCC(=O)c1c(-c2ccc(C(C)=O)cc2)c2cc(Cl)ccc2c(=O)n1Cc1ccc(S(C)(=O)=O)cc1,,ClCCl,,C1CCOC1,,test
US06689909B1,C[C@@](O[Si](C)(C)C)(C(=O)Nc1ccc(I)c([N+](=O)[O-])c1Cl)C(F)(F)F>>C[C@@](O)(C(=O)Nc1ccc(I)c([N+](=O)[O-])c1Cl)C(F)(F)F,,CO,,Cl,,test
US04925849,COC(=O)CP(=O)(OC)OC.O=Cc1c(-c2ccccc2)nn2ccccc12>>COC(=O)C=Cc1c(-c2ccccc2)nn2ccccc12,,Cc1ccccc1,,[H-].[Na+],,test
US06455507B1,CC(=O)O[C@@H]1[C@H](OC(C)=O)[C@H](OC(C)=O)CO[C@H]1n1c(Br)nc2cc(F)c(F)cc21>>O[C@@H]1[C@H](O)[C@H](O)CO[C@H]1n1c(Br)nc2cc(F)c(F)cc21,,C1COCCO1,,[Li+].[OH-],,test
US20090143361A1,COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)cc(Cl)c4)n3c2n1.COc1ccccc1B(O)O>>COc1ccc2nc(C)c3c(C)nc(-c4ccccc4OC)n3c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US04771046,COC(=N)CCl.CON=C1CCNCC1.Cl>>CON=C1CCN(C(=N)CCl)CC1.Cl,,CO,,,,test
US20120270868A1,C=CC(=O)C=C.N#Cc1ccc(-c2cnn(Cc3cccc(C(=O)Nc4nc5c(s4)C[C@@H](N)CC5)c3)c2)cc1>>N#Cc1ccc(-c2cnn(Cc3cccc(C(=O)Nc4nc5c(s4)C[C@@H](N4CCC(=O)CC4)CC5)c3)c2)cc1,,CO,ClCCl,,,test
US20100240642A1,CC(C)(C)c1ccc(O)cc1.CCOC(=O)C1=Nc2ccccc2C1=[N+]=[N-]>>CCOC(=O)c1[nH]c2ccccc2c1Oc1ccc(C(C)(C)C)cc1,,ClCCCl,,,,test
US20090131503A1,CCN(C(=O)OC(C)(C)C)C1CCCC(c2c[nH]c3ccc([N+](=O)[O-])cc23)C1>>CCN(C(=O)OC(C)(C)C)C1CCCC(c2c[nH]c3ccc(N)cc23)C1,[Ni],CO,O,NN,,test
US20100234367A1,C[C@H]1COc2c(F)c(F)c(N)c3c(=O)c(C#N)cn1c23.N[C@@H]1CC[C@@H](c2cccnc2)C1>>C[C@H]1COc2c(N[C@H]3CC[C@H](c4cccnc4)C3)c(F)c(N)c3c(=O)c(C#N)cn1c23,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US20070287724A1,Nc1nc2ccccc2c2c1nc(CN1C(=O)c3ccccc3C1=O)n2CC1(O)CCC1>>NCc1nc2c(N)nc3ccccc3c2n1CC1(O)CCC1,,CCO,,NN,,test
US20130158025A1,Cc1cc2nc(Cl)cc(-c3cc(F)cc(F)c3)n2n1.O=C1CCC(=O)N1I>>Cc1nn2c(-c3cc(F)cc(F)c3)cc(Cl)nc2c1I,,ClCCl,,,,test
US20110275611A1,CC1(C)OB(c2ccc(C#N)c(F)c2)OC1(C)C.Nc1nc(Cl)cc(N2CCOC(c3nc4c([nH]3)CCCC4)C2)n1>>N#Cc1ccc(-c2cc(N3CCOC(c4nc5c([nH]4)CCCC5)C3)nc(N)n2)cc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090326009A1,C1CCNC1.COc1ccccc1-c1ccc2c(c1CCl)C(C)=CC(C)(C)N2>>COc1ccccc1-c1ccc2c(c1CN1CCCC1)C(C)=CC(C)(C)N2,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20130150343A1,CC(C)[Si](OC[C@H]1CCN(c2nnc3ccc(O[C@@H]4CC[C@H](N)c5ccccc54)cn23)C1)(C(C)C)C(C)C.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCC(O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]5C)n4c3)c3ccccc32)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20050267215A1,CC12CCC(C1)C(C)(C)C2NC(=O)CCl.c1ccc(NC2CCCCC2)cc1>>CC12CCC(C1)C(C)(C)C2NCC(=O)N(c1ccccc1)C1CCCCC1,,C1CCOC1,,O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20090054428A1,Cc1nc(Cl)c(CO)cc1N(C)c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1>>Cc1ncc(CO)cc1N(C)c1ccnc(Nc2cc(N3CCOCC3)cc(N3CCOCC3)c2)n1,[Pd],CCO,O,O=C([O-])[O-].[K+].[K+],,test
US04533666,COc1ccc(-c2ccc(-c3ccc(F)cc3)nc2-c2ccc(OC)cc2)cc1.Cc1ccc(S(=O)(=O)O)cc1>>COc1ccc(-c2ccc(-c3ccc(F)cc3)nc2-c2ccc(OC)cc2)cc1.Cc1ccc(S(=O)(=O)O)cc1,,CCOCC,,,,test
US20060052396A1,CN1CCNCC1.Cc1cc(S(=O)(=O)O)ccc1N>>Cc1cc(S(=O)(=O)N2CCN(C)CC2)ccc1N,,O=S(Cl)Cl,,,,test
US20100004238A1,COC(=O)c1cnn2cc(O)ccc12.O=[N+]([O-])c1ccc(F)c(Cl)c1>>COC(=O)c1cnn2cc(Oc3ccc([N+](=O)[O-])cc3Cl)ccc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110288065A1,CS(=O)(=O)N1CCNCC1.C[C@H](Nc1nc(Cl)cc(Cl)n1)c1ccc(Cl)cc1>>C[C@H](Nc1nc(Cl)cc(N2CCN(S(C)(=O)=O)CC2)n1)c1ccc(Cl)cc1,,CCCCO,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20060058264A1,CCC(=O)OC(=O)CC.COC(=O)[C@@H]1C[C@H](O)C(=O)[C@H]2[C@@]1(C)CC[C@@H]1C(=O)O[C@H](c3ccoc3)C[C@]21C>>CCC(=O)O[C@H]1C[C@@H](C(=O)OC)[C@]2(C)CC[C@H]3C(=O)O[C@H](c4ccoc4)C[C@]3(C)[C@H]2C1=O,CN(C)c1ccncc1,ClCCl,,CO,,test
US20040082651A1,CC(C)C=O.COC(OC)C(C)(C)C(=O)C(C)Br>>COC(OC)C(C)(C)C(=O)C(C)C(O)C(C)C,,C1CCOC1,,[I-].[Li+],,test
US20070232619A1,CCO.O=C1Cc2cc(Cl)ccc2N1>>CCC1C(=O)Nc2ccc(Cl)cc21,[Ni],,,,,test
US08198302B2,C=CCBr.CCOC1Oc2cccc(O)c2O1>>C=CCOc1cccc2c1OC(OCC)O2,,CN(C)C=O,,O,[H-].[Na+],test
US20020137939A1,O=C(NCCc1ccc(Cl)cc1Cl)c1ccc(Cl)nc1.[N-]=[N+]=[N-]>>[N-]=[N+]=Nc1ccc(C(=O)NCCc2ccc(Cl)cc2Cl)cn1,,CS(C)=O,,CCOC(C)=O,,test
US20120035208A1,COc1cc(B(O)O)ccn1.Cn1ncc2c(Cl)cc(Cl)nc21>>COc1cc(-c2cc(Cl)c3cnn(C)c3n2)ccn1,,CC#N,,CC(=O)[O-].[K+],,test
US20130310357A1,CC(C)(C)c1cc(NC(=O)Nc2ccc(NC(=O)c3ccc(OC4CCNC4)cn3)cc2)no1.CN(C)C(=O)CCl>>CN(C)C(=O)CN1CCC(Oc2ccc(C(=O)Nc3ccc(NC(=O)Nc4cc(C(C)(C)C)on4)cc3)nc2)C1,,CC#N,,Cl,,test
US04159984,COC(=O)C1NC2(C(=O)Cc3ccccc3)C(=O)N(C(C(=O)OC(c3ccccc3)c3ccccc3)=C(C)C)C2O1>>CC(C)=C(C(=O)OC(c1ccccc1)c1ccccc1)N1C(=O)C2(C(=O)Cc3ccccc3)NC(C(=O)O)OC12,,CC(C)=O,O,Cl,[Na+].[OH-],test
US08524900B2,CC(C)(C)OC(=O)NCc1nnc2ccc(/C=N/O)nn12.O=C1CCC(=O)N1Cl>>CC(C)(C)OC(=O)NCc1nnc2ccc(/C(Cl)=N/O)nn12,,CN(C)C=O,,,,test
US20160060257A1,CC(C)(C)OC(=O)N1CC(=O)C1.Cc1ccc(S(=O)(=O)n2c(I)cc3c(Cl)ccnc32)cc1>>CC(C)(C)OC(=O)N1CC(O)(c2cc3c(Cl)ccnc3[nH]2)C1,,C1CCOC1,,[Li]CCCC,,test
US20090281103A1,COC/C=C/c1cc(C(=O)NC2CC2)cc(OC)n1>>COCCCc1cc(C(=O)NC2CC2)cc(OC)n1,[Pd],CCOC(C)=O,,,,test
US20080038242A1,CCI.OCCCCOc1cc(CNc2nc3ccccc3n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)ccc1O>>CCOc1ccc(CNc2nc3ccccc3n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1OCCCCO,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04945090,CCC(N)=NO.COCc1c(C(=O)O)ncc2[nH]c3cccc(Oc4ccc(Cl)cc4)c3c12>>CCc1noc(-c2ncc3[nH]c4cccc(Oc5ccc(Cl)cc5)c4c3c2COC)n1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20080176829A1,CC1c2c(ccc3[nH]ccc23)OCCN1C(=O)OC(C)(C)C.Cc1nc(S(=O)(=O)Cl)cn1C>>Cc1nc(S(=O)(=O)n2ccc3c4c(ccc32)OCCN(C(=O)OC(C)(C)C)C4C)cn1C,,CN(C)C=O,,[H-].[Na+],,test
US20120101136A1,CCOC(=O)CCCCOc1ccc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)c(CC)c1>>CCc1cc(OCCCCC(=O)O)ccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1,,CC(C)O,O,[Na+].[OH-],,test
US20060025423A1,CC(C)(C)OC(=O)N1CCC[C@H]1CO.COc1nc(Cl)c(Cl)nc1N(COCC[Si](C)(C)C)S(=O)(=O)c1cccc(Cl)c1Cl.Cl>>COc1nc(OC[C@H]2CCCN2)c(Cl)nc1NS(=O)(=O)c1cccc(Cl)c1Cl.Cl,,CN1CCCC1=O,,[H-].[Na+],,test
US20130150407A1,COC(=O)Cc1cc2ccc(F)cc2c(C2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)c1C>>Cc1c(CC(=O)O)cc2ccc(F)cc2c1C1CCN(S(=O)(=O)c2cc(Cl)ccc2Cl)CC1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20070184979A1,CC(C)(C)OC(=O)/C=C/c1ccn(S(=O)(=O)c2ccc(CBr)cc2)c1.CC(C)(C)[Si](C)(C)OCCNCCc1c[nH]c2ccccc12>>CC(C)(C)OC(=O)/C=C/c1ccn(S(=O)(=O)c2ccc(CN(CCO[Si](C)(C)C(C)(C)C)CCc3c[nH]c4ccccc34)cc2)c1,,CCO,,,,test
US03941802,NN=C(c1cc(Cl)ccc1N)c1ccccc1Cl>>Nc1ccc(Cl)cc1Cc1ccccc1Cl,,OCCOCCO,,[K+].[OH-],,test
US20130196974A1,C=C(C)CN.O=S1(=O)CCN(c2cc(Cl)c3cc(OC(F)(F)F)ccc3n2)Cc2ccccc21>>C=C(C)CNc1cc(N2CCS(=O)(=O)c3ccccc3C2)nc2ccc(C)cc12,,O,,CN1CCCC1=O,,test
US20100216814A1,CC(=CBr)C1CCCCC1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>C/C(=C/n1c2c(c3cc(C)ccc31)CN(C)CC2)C1CCCCC1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20130345123A1,C=CC(=O)OC.CC(C)(C)OC(=O)N[C@H]1CCCCNC1=O>>COC(=O)CCN1CCCC[C@H](NC(=O)OC(C)(C)C)C1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05096913,Clc1nc[nH]n1.O=C(c1ccc(Cl)cc1)C(Br)CCCl>>O=C(c1ccc(Cl)cc1)C1(n2cnc(Cl)n2)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150299210A1,CN(CCN)C(=O)OC(C)(C)C.COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)O)c1nnc(C)n1-2>>COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCN(C)C(=O)OC(C)(C)C)c1nnc(C)n1-2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050101063A1,CCCCCCc1ccc(C#C[Si](C)(C)C)cc1>>C#Cc1ccc(CCCCCC)cc1,,ClCCl,,CO,O=C([O-])[O-].[K+].[K+],test
US20140235584A1,COCCl.O=[N+]([O-])c1c[nH]nn1>>COCn1cc([N+](=O)[O-])nn1,,CCOC(C)=O,O,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120035206A1,O=C(Cl)CCl.O=C1C(=CO)SCc2ccccc21>>O=C1/C(=C/Cl)SCc2ccccc21,,ClCCl,,,,test
US05977025,CC1=C(c2ccccc2)C(=O)N(C(C)(C)C(=O)O)CO1.CCI>>CCOC(=O)C(C)(C)N1COC(C)=C(c2ccccc2)C1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160143915A1,COc1cc(C#N)c(Cl)cc1COC1CCCCO1.NO>>COc1cc(C(=N)NO)c(Cl)cc1COC1CCCCO1,,CCO,,CCN(CC)CC,Cl,test
US04698340,CI.Cc1nc(-c2ccccc2)nc(-c2cccc([N+](=O)[O-])c2)c1C(=O)NCCN(C)C>>Cc1nc(-c2ccccc2)nc(-c2cccc([N+](=O)[O-])c2)c1C(=O)NCC[N+](C)(C)C.[I-],,CCOC(C)=O,,,,test
US20160151249A1,C=C(C)C(=O)OCCNC(=O)NCCP(=O)(OCC)OCC>>C=C(C)C(=O)OCCNC(=O)NCCP(=O)(O)O,,ClCCl,,C[Si](C)(C)Br,,test
US20150031670A1,CC(C)(C)OO.O=C(NCc1cc(F)cc(Cl)c1)C1CCCCN(c2ccccc2)C1=O>>O=C(NCc1cc(F)cc(Cl)c1)C1(O)CCCCN(c2ccccc2)C1=O,,CC(C)(C)O,,C,C[O-].[Na+],test
US20030229079A1,Brc1cc(Br)cc(Cc2ccccc2)c1.CON(C)C(=O)Cc1cnccn1>>O=C(c1cc(Br)cc(Cc2ccccc2)c1)c1cnccn1,,CCOC(C)=O,,CCOCC,[Li]CCCC,test
US20160009704A1,CC(C)(C)OC(=O)c1cn(CCCCO)nn1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)c1cn(CCCCOS(C)(=O)=O)nn1,,ClCCl,,,,test
US05135947,O=C1CCC(=O)N1Br.c1ccc(CCCOc2cccc3ccccc23)cc1>>BrC(CCOc1cccc2ccccc12)c1ccccc1,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US05650410,C1COCCN1.CCOC(=O)c1c(CCl)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC)c1>>CCOC(=O)c1c(CN2CCOCC2)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20090149456A1,CN(C)CCOc1cccc(N)c1.O=C(Nc1cccc(-c2nn3ccccc3c2-c2ccnc(Cl)n2)c1)C(F)(F)F>>CN(C)CCOc1cccc(Nc2nccc(-c3c(-c4cccc(NC(=O)C(F)(F)F)c4)nn4ccccc34)n2)c1,Cl,CC(C)O,ClCCl,,,test
US20080132496A1,Cc1cc(C(=O)N[C@@H](C)c2nc3cc([N+](=O)[O-])ccc3[nH]2)ccc1C(=O)N1CCCC1>>Cc1cc(C(=O)N[C@@H](C)c2nc3cc(N)ccc3[nH]2)ccc1C(=O)N1CCCC1,[Pd],CO,,[H][H],,test
US20040209901A1,C[C@@H](N)CO.Cc1cc(F)ccc1-c1nc(S(C)(=O)=O)nc2c1ccc(=O)n2-c1c(F)cccc1F>>Cc1cc(F)ccc1-c1nc(N[C@H](C)CO)nc2c1ccc(=O)n2-c1c(F)cccc1F,,C1CCOC1,,,,test
US20110201604A1,CCNc1ccc(C(=O)OC)cc1[N+](=O)[O-]>>CCNc1ccc(C(=O)OC)cc1N,[Pd],CCOC(C)=O,CO,,,test
US04683303,C=C(C)C(C(=O)OC)N1C(=O)[C@@H](NC(=O)OCc2ccccc2)[C@@H]1OC(C)=O>>COC(=O)C(=C(C)C)N1C(=O)[C@@H](NC(=O)OCc2ccccc2)[C@@H]1OC(C)=O,,ClCCl,,CCN(CC)CC,,test
US20090115327A1,CN(C)c1ccnc(I)c1.OB(O)c1ccc(F)cc1F>>CN(C)c1ccnc(-c2ccc(F)cc2F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[K+].[K+],,test
US20070254881A1,CI.COc1ccc(-n2nc(C(=O)N3CCCN3)cc2-c2ccccn2)nn1>>COc1ccc(-n2nc(C(=O)N3CCCN3C)cc2-c2ccccn2)nn1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20130131050A1,CCOC(=O)c1cscc1N=C=S.Nc1ccc(OCC(F)(F)F)cc1>>O=c1c2cscc2[nH]c(=S)n1-c1ccc(OCC(F)(F)F)cc1,,CC#N,CCO,CC(C)(C)[O-].[K+],,test
US05073629,C=CCCCC(O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1>>C=CCCCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1,,ClCCl,O,CS(C)=O,O=C(Cl)C(=O)Cl,test
US04096264,O=[N+]([O-])c1cnc2ccc(Sc3ccccc3)cn12>>Nc1cnc2ccc(Sc3ccccc3)cn12,[Pd],C1COCCO1,,[H][H],,test
US04642308,COc1ccc(C(=O)O)cc1.Nc1ccc2ccc(Oc3cccc(F)c3)nc2n1>>COc1ccc(C(=O)Nc2ccc3ccc(Oc4cccc(F)c4)nc3n2)cc1,,O,,CCO,,test
US20120202794A1,CC(C)C[C@H]1C(=O)N[C@@H](c2ccccc2)CN1C(=O)c1cc(-c2ccc(F)cc2)on1.CI>>CC(C)C[C@H]1C(=O)N(C)[C@@H](c2ccccc2)CN1C(=O)c1cc(-c2ccc(F)cc2)on1,,CN(C)C=O,,[H-].[Na+],,test
US20050214204A1,N[C@H]1CCCN[C@H]1c1ccccc1.O=C(Cl)OCc1ccccc1>>O=C(N[C@H]1CCCN[C@H]1c1ccccc1)OCc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110046143A1,CN(C(=O)c1ccccc1C(F)(F)F)C1CCN(c2nnc(Cl)c3ccccc23)CC1.OB(O)c1ccc(C(F)(F)F)cc1>>CN(C(=O)c1ccccc1C(F)(F)F)C1CCN(c2nnc(-c3ccc(C(F)(F)F)cc3)c3ccccc23)CC1.Cl,,O,,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US20040220222A1,CC(C(=O)NC1C(=O)N(C)c2ccccc2-c2ccccc21)C(=O)OC(C)(C)C>>CC(C(=O)O)C(=O)NC1C(=O)N(C)c2ccccc2-c2ccccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150087646A1,C#Cc1cccc(Cl)c1F.COc1cc(-c2nn(-c3c(Cl)cccc3Cl)c(=O)[nH]2)ccc1I>>COc1cc(-c2nn(-c3c(Cl)cccc3Cl)c(=O)[nH]2)ccc1C#Cc1cccc(Cl)c1F,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CS(C)=O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080214529A1,CI.COC(=O)C1(NN=CCC(C)(C)C)CCCC1>>COC(=O)C1(N(C)N=CCC(C)(C)C)CCCC1,,CO,,C[O-].[Na+],,test
US20160052898A1,O=C(Nc1ccc(-c2ccccc2)cc1)c1ccc(C(F)(F)F)c([N+](=O)[O-])c1>>Nc1cc(C(=O)Nc2ccc(-c3ccccc3)cc2)ccc1C(F)(F)F,[Pd],C1CCOC1,CCOC(C)=O,,,test
US20100152265A1,O=C(NCCBr)OCc1ccccc1.Oc1ccc2c(C3CC3)nn(Cc3ccccc3)c2c1>>O=C(NCCOc1ccc2c(C3CC3)nn(Cc3ccccc3)c2c1)OCc1ccccc1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US04908363,CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O.Nn1ccnc1N1CCOCC1>>CC(C)(C)c1cc(C=Nn2ccnc2N2CCOCC2)cc(C(C)(C)C)c1O,,CCO,,Cl,,test
US04182881,ClP(Cl)(Cl)(Cl)Cl.NC(=O)Cc1ccccc1.O=CO>>O=C(Cc1ccccc1)NP(=O)(Cl)Cl,,ClC(Cl)(Cl)Cl,,Cl,,test
US20110077235A1,CNC(=O)[C@@H]1CCCNC1.Cc1cc2nc(NC(=O)c3ccc(C(C)(C)O)cc3)cc(Cl)n2n1>>CNC(=O)[C@@H]1CCCN(c2cc(NC(=O)c3ccc(C(C)(C)O)cc3)nc3ccnn23)C1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20030158413A1,COC(=O)c1ccc2c(c1)SCCC2N.O=C(Cl)OCc1ccccc1>>COC(=O)c1ccc2c(c1)SCCC2NC(=O)OCc1ccccc1,,CCOC(C)=O,,O=C([O-])O.[Na+],,test
US20120172358A1,CC(C)(C)OC(=O)N1CCC(CCCC(=O)O)CC1.CSc1ccc(N)cc1F>>CSc1ccc(NC(=O)CCCC2CCN(C(=O)OC(C)(C)C)CC2)cc1F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CCN=C=NCCCN(C)C,test
US20110112103A1,CCOC(=O)CNC(=O)c1nc(CC2CCN(c3ccc(C=O)cc3)CC2)nc(C)c1OCc1ccccc1.OCCCO>>CCOC(=O)CNC(=O)c1nc(CC2CCN(c3ccc(C4OCCCO4)cc3)CC2)nc(C)c1OCc1ccccc1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20120082702A1,CC(C)(C)OC(=O)N1CCCC2(CC(c3ccccc3)=NO2)C1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.c1ccc(C2=NOC3(CCCNC3)C2)cc1,,ClCCl,,,,test
US20150166558A1,Fc1cccc(C(F)(F)F)c1CBr.O=c1[nH]c2c(c(=O)[nH]1)C1(CCN(Cc3ccccc3)CC1)OC2>>O=c1[nH]c(=O)n(Cc2c(F)cccc2C(F)(F)F)c2c1C1(CCN(Cc3ccccc3)CC1)OC2,,CN1CCCC1=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20080021024A1,COc1cccc(CNC(=O)c2cc(CNC3CCc4c3ccc(C(=O)OC(C)(C)C)c4C)ncn2)c1>>COc1cccc(CNC(=O)c2cc(CNC3CCc4c3ccc(C(=O)O)c4C)ncn2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130345221A1,COC(=O)c1cc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)oc1C>>Cc1oc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)cc1CO,,CCOCC,,CC(C)C[Al+]CC(C)C.[H-],,test
US04242519,CI.COC(=O)C(SC)c1cccc(C(OC)(OC)c2ccccc2)c1>>COC(=O)C(C)(SC)c1cccc(C(OC)(OC)c2ccccc2)c1,,CS(C)=O,,[H-].[Na+],[Cl-].[NH4+],test
US20150057265A1,C=CB1OC(C)(C)C(C)(C)O1.COC(=O)c1sc2cc(Br)cnc2c1NC(=O)OC(C)(C)C>>C=Cc1cnc2c(NC(=O)OC(C)(C)C)c(C(=O)OC)sc2c1,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,C1COCCO1,O,CCN(C(C)C)C(C)C,,test
US20150274661A1,CCOC(=O)c1cc2cc(Br)ccc2[nH]1.COc1ccc(CBr)cc1>>CCOC(=O)c1cc2cc(Br)ccc2n1Cc1ccc(OC)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20040147535A1,Nc1cc(CNc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)ccn1.O=C=NCc1ccccc1>>O=C(NCc1ccccc1)Nc1cc(CNc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)ccn1,,ClCCl,,,,test
US20030078426A1,Cc1cc(C)cc(Sc2ccc3nc(CCl)n(C)c3n2)c1.O=[N+]([O-])O>>Cc1cc(Sc2ccc3nc(CCl)n(C)c3n2)cc(C)c1[N+](=O)[O-],,CC(=O)O,,O=S(=O)(O)O,,test
US20120107307A1,COC(=O)c1cc(C)c(=O)n(C)c1Nc1ccc(I)cc1F>>Cc1cc(C(=O)O)c(Nc2ccc(I)cc2F)n(C)c1=O,,O,,C1CCOC1,[Li+].[OH-],test
US20100029670A1,CC(C)[C@@H](N)CO.CCOc1c(Nc2ccc(Cl)c(S(=O)(=O)N(C)OC)c2O)c(=O)c1=O>>COC[C@H](Nc1c(Nc2ccc(Cl)c(S(=O)(=O)N(C)OC)c2O)c(=O)c1=O)C(C)C,,CCO,,CCN(CC)CC,,test
US04324894,C1COCCN1.Cc1c(N)nc(Br)c2ccccc12>>Cc1c(N)nc(N2CCOCC2)c2ccccc12,,O,,,,test
US20040067951A1,Nc1ccc(-c2cn3ccnc3c(N)n2)cc1.O=C=Nc1ccccc1>>Nc1nc(-c2ccc(NC(=O)Nc3ccccc3)cc2)cn2ccnc12,,Cc1ccccc1,,CN1CCOCC1,,test
US20140275044A1,O=C(N=C=S)c1ccccc1.O=C(OCc1ccccc1)N1CC2CONC2(c2cc(Br)ccc2F)C1>>O=C(NC(=S)N1OCC2CN(C(=O)OCc3ccccc3)CC21c1cc(Br)ccc1F)c1ccccc1,,C1CCOC1,,,,test
US20040106653A1,COCCl.O=C(NCCc1ccc(S(=O)(=O)c2ccc(OCc3ccccc3)c(O)c2)cc1)C(F)(F)F>>COCOc1cc(S(=O)(=O)c2ccc(CCNC(=O)C(F)(F)F)cc2)ccc1OCc1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150344466A1,BrCCCCCc1ccccc1.CCOC(=O)c1cc(CO)on1>>CCOC(=O)c1cc(COCCCCCc2ccccc2)on1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20100204327A1,CC(C)CCC1C(=O)CCCC1=O.CC(C)CO>>CC(C)CCC1=C(OCC(C)C)CCCC1=O,Cc1ccc(S(=O)(=O)O)cc1,c1ccccc1,,O,,test
US04323634,CCCCCCCCCCCC(=O)NCCCN(C)C.COS(=O)(=O)OC>>CCCCCCCCCCCC(=O)NCCC[N+](C)(C)C.COS(=O)(=O)[O-],,CC(C)=O,,,,test
US20080312226A1,O=C(OCC(Cl)(Cl)Cl)N(C(=O)OCC(Cl)(Cl)Cl)c1cnc2ccccc2c1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>O=C(Nc1cnc2ccccc2c1)N1CCN(c2nc(-c3ccccc3)ns2)CC1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20120301401A1,CC(C)(C)O.CC(C)(C)OC(=O)CBr.OCCOCc1ccccc1>>CCCCOC(=O)COCCOCc1ccccc1,,CC(C)(C)O,,CC(C)(C)[O-].[K+],,test
US07015218B1,C1COCCN1.N#Cc1cc([N+](=O)[O-])ccc1Cl>>N#Cc1cc([N+](=O)[O-])ccc1N1CCOCC1,,CCO,,,,test
US20030199440A1,CC(C)(C)OC(=O)[C@H]1CCCCN1.O=S(=O)(Cl)c1ccc2c(Cl)cnc(Cl)c2c1>>CC(C)(C)OC(=O)[C@H]1CCCCN1S(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1,,ClCCl,,CCN(CC)CC,,test
US20120248969A1,CC(C)C(=O)Nc1ccc(Br)cc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)C(=S)Nc1ccc(Br)cc1,,Cc1ccccc1,,,,test
US20070142331A1,Cc1cc(C)c(CO)c(C)c1.O=C1CCC(=O)O1>>Cc1cc(C)c(COC(=O)CCC(=O)O)c(C)c1,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150368247A1,C[C@@H]1CC[C@@H](Cn2cnc3nc(C#N)nc(-c4cc(Cl)ccn4)c32)CC1.NO>>C[C@@H]1CC[C@@H](Cn2cnc3nc(C(=N)NO)nc(-c4cc(Cl)ccn4)c32)CC1,,CCO,O,Cl,O=C([O-])O.[Na+],test
US20150376208A1,CCOC(=O)c1sc(-c2ccnc(Cl)c2)cc1NC[C@@H](C)N>>C[C@@H]1CNc2cc(-c3ccnc(Cl)c3)sc2C(=O)N1,,CCO,O,C,C[O-].[Na+],test
US20040048908A1,N.O=C(O)/C=C/c1cnoc1-c1ccccc1>>NC(=O)/C=C/c1cnoc1-c1ccccc1,,C1CCOC1,O,CCN(CC)CC,CCOC(=O)Cl,test
US20110077290A1,CNN=CC(C)=O.O=CC(=O)c1cccc(C(F)(F)F)c1>>CC(=O)c1nn(C)c(-c2cccc(C(F)(F)F)c2)c1O,,CC(=O)O,,CO,ClC(Cl)Cl,test
US20130210804A1,COC(=O)[C@H]1CC[C@H]2CSc3ccccc3C(=O)N2C1>>O=C(O)C1CCC2CSc3ccccc3C(=O)N2C1,,C1CCOC1,CCO,[Na+].[OH-],,test
US05519034,COc1ccc(CCNC(=O)C2(c3ccc(Cl)cc3Cl)CC2)cc1F>>COc1cc2c(cc1F)CCN=C2C1(c2ccc(Cl)cc2Cl)CC1,,ClC(Cl)Cl,,,,test
US20120223634A1,CC1(C)OB(c2ccccc2N)OC1(C)C.COc1ccc(Br)c(C#N)c1>>COc1ccc2c(c1)c(N)nc1ccccc12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,Cc1ccccc1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20110263626A1,N#Cc1ccc(F)c(C(F)(F)F)c1.O=C(NC1(C(=O)NCc2ccc(O)cc2)CC1)c1cncnc1>>N#Cc1ccc(Oc2ccc(CNC(=O)C3(NC(=O)c4cncnc4)CC3)cc2)c(C(F)(F)F)c1,,CC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20150315198A1,Brc1nccc2cnn(Cc3ccc(Cn4cccn4)cc3)c12.NCc1ccc2c(N)nccc2c1>>Nc1nccc2cc(CNc3nccc4cnn(Cc5ccc(Cn6cccn6)cc5)c34)ccc12,,CCCCO,,,,test
US20050020634A1,CCOC(=O)C=Cc1cccc(-c2c(CC(=O)Nc3ccc(F)cc3C(F)(F)F)c(=O)oc3cc(Cl)c(C)cc23)c1>>CCOC(=O)CCc1cccc(-c2c(CC(=O)Nc3ccc(F)cc3C(F)(F)F)c(=O)oc3cc(Cl)c(C)cc23)c1,[Ni],C1CCOC1,CCO,,,test
US20040152690A1,C[C@@H]1CN(c2nc3cc(C(F)(F)F)cc(Cl)c3[nH]2)CCN1.FC(F)(F)c1cccnc1Cl>>C[C@@H]1CN(c2nc3cc(C(F)(F)F)cc(Cl)c3[nH]2)CCN1c1ncccc1C(F)(F)F,,O,,CCN(C(C)C)C(C)C,,test
US20080318944A1,CON(C)C(=O)C1CCCCN1C(=O)OC(C)(C)C.C[Si](C)(C)CCOCn1ccc2ccccc21>>CC(C)(C)OC(=O)N1CCCCC1C(=O)c1cc2ccccc2n1COCC[Si](C)(C)C,,COCCOC,,[Li]CCCC,[Cl-].[NH4+],test
US20080004323A1,Cc1ccc(N)cc1.O=C(Cl)C=CSc1ccccc1>>Cc1ccc(NC(=O)C=CSc2ccccc2)cc1,,CC#N,,Cl,,test
US06391991B1,C=CC(=O)Cl.Cc1ccc(C)cc1>>Cc1ccc(C)c2c1CCC2=O,,ClCCl,O,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20160039825A1,CCOC(=O)c1cc2n(c1)CCCN(C(=O)OCc1cc(Cl)cc(C(F)(F)F)c1)C2>>O=C(O)c1cc2n(c1)CCCN(C(=O)OCc1cc(Cl)cc(C(F)(F)F)c1)C2,,CCO,O,Cl,[Na+].[OH-],test
US04171365,CCI.COc1ccc(OCCCCCCc2c(C)n[nH]c2C)c(Cl)c1>>CCn1nc(C)c(CCCCCCOc2ccc(OC)cc2Cl)c1C,,CN(C)C=O,,[H-].[Na+],,test
US20100179137A1,CCc1cccc(OCc2c(Cl)cc(Cl)c(=O)n2CCc2ccc(C(=O)O)cc2)c1.O=C(n1ccnc1)n1ccnc1>>CCc1cccc(OCc2c(Cl)cc(Cl)c(=O)n2CCc2ccc(C(=O)n3ccnc3)cc2)c1,,CN(C)C=O,,CCOC(C)=O,O,test
US20020193596A1,COC(=O)c1ccc(OCc2cccnc2)cc1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1ccc(OCc2cccnc2)cc1OS(=O)(=O)C(F)(F)F,,c1ccncc1,,O,[Na+].[OH-],test
US20150191460A1,COC(=O)c1ccnc(N)c1.Cc1cc(Br)ccc1C(=O)O.Nc1ccccc1N.OB(O)c1ccc(C(F)(F)F)cc1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)ccc1C(=O)Nc1cc(-c2nc3ccccc3[nH]2)ccn1,,CC(=O)O,,,,test
US20040138214A1,CC#CCn1c(N2CCCC(NC(=O)OC(C)(C)C)C2)nc2c1c(=O)n(CC(=O)NCc1ccccc1N)c(=O)n2C>>CC#CCn1c(N2CCCC(NC(=O)OC(C)(C)C)C2)nc2c1c(=O)n(CC1=Nc3ccccc3CN1)c(=O)n2C,,CC(=O)O,,,,test
US20100022484A1,CC(N)=CC(=O)c1ccc(C(C)(C)C)cc1.CCCOC(=O)CC(C)=O.Cc1cc(=O)c2cccc(C=O)c2o1>>CCCOC(=O)C1=C(C)NC(C)=C(C(=O)c2ccc(C(C)(C)C)cc2)C1c1cccc2c(=O)cc(C)oc12,,CC(C)O,,CC(=O)O,,test
US20060216265A1,CC(C)(C)OC(=O)NCCN.O=C(O)CCCCCNC(=O)CCNC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NCCNC(=O)CCCCCNC(=O)CCNC(=O)OCc1ccccc1,,CN(C)C=O,,CCN=C=NCCCN(C)C,,test
US04600709,CCOC(=O)C(Cl)Cl.Cc1ccc(S(=O)(=O)c2cc(O)c(O)cc2C)cc1>>CCOC(=O)C1Oc2cc(C)c(S(=O)(=O)c3ccc(C)cc3)cc2O1,,COCCOC,,Cl,O=C([O-])[O-].[K+].[K+],test
US20040006093A1,CC[C@H](C)[C@H](N)C(=O)OC.Cc1ccc(S(=O)(=O)N2CCC[C@H]2C(=O)O)cc1>>CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(C)cc1)C(=O)O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US05102877,C=CCOC(=O)N1CC=C(C#C[Si](C)(C)C)C1.O=C([O-])O>>C=CCOC(=O)N1CC=C(C(C)=O)C1,O=S(=O)(O)O,C1CCOC1,O,CCOC(C)=O,,test
US04775692,C=[N+]=[N-].O=C(O)c1ccc(Cl)cc1>>COC(=O)c1ccc(Cl)cc1,,CCOCC,,,,test
US20100087502A1,Oc1cccc2c1cnn2-c1ccc(OCc2ccccc2)c(F)c1>>Oc1ccc(-n2ncc3c(O)cccc32)cc1F,[Pd],CCOC(C)=O,,,,test
US06172066B2,N#CC1(c2ccccc2)CCC(=O)CC1.NCCCN>>N#CC1(c2ccccc2)CCC(NCCCN)CC1,Cc1ccc(S(=O)(=O)O)cc1,c1ccccc1,,,,test
US07407968B2,NCC1CCOCC1.O=C(c1ccc(F)c([N+](=O)[O-])c1)N(CC(F)(F)F)CC(F)(F)F>>O=C(c1ccc(NCC2CCOCC2)c([N+](=O)[O-])c1)N(CC(F)(F)F)CC(F)(F)F,,CCO,,CCN(CC)CC,,test
US20150225400A1,CCOc1ccc(F)c(-c2cc(C)nc(C=O)c2C)c1.CN1CCC(N)C1=O>>CCOc1ccc(F)c(-c2cc(C)nc(/C=N/C3CCN(C)C3=O)c2C)c1,,ClCCl,,O=S(=O)([O-])[O-].[Mg+2],,test
US05204364,C=C1c2cc(C(=O)OCC)ccc2CCC1n1ccnc1>>C=C1c2cc(C(=O)O)ccc2CCC1n1ccnc1,,O,,CCO,[Na+].[OH-],test
US05025031,OCCCl.Oc1ccc(-n2cncn2)cc1>>OCCOc1ccc(-n2cncn2)cc1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05120840,CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=C(N)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C.O=CO>>CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=C(NC=O)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,O,CC(=O)OC(C)=O,,test
US20090215186A1,O=C1c2c(O)cc(O)cc2O[C@H](c2ccc(O)c(O)c2)[C@H]1O.Oc1cc(O)c2c(c1)O[C@H](c1ccc(O)c(O)c1)[C@@H](O)C2>>Oc1cc(O)c2c(c1)O[C@H](c1ccc(O)c(O)c1)[C@@H](O)[C@@H]2c1c(O)cc(O)c2c1O[C@H](c1ccc(O)c(O)c1)[C@@H](O)C2,,CCO,,Cl,[BH4-].[Na+],test
US20160046596A1,CC(=O)[O-].CC1(C)OCc2c(CCl)cncc2O1>>Cc1cnc(C)c(O)c1CO,[Pd],,,Cl,,test
US20070010573A1,C=CCOC(=O)[C@@H](N)C(C)C.O=S1(=O)CCCO1>>C=CCC(=O)[C@@H](NCCCS(=O)(=O)O)C(C)C,,C1COCCO1,CO,C1CCOC1,,test
US20090124596A1,C=O.CC(C)(C)OC(=O)N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccc(O)cc4C=O)c3)c2=O)CC1.COC[C@H](C)N.O=Cc1cn2cc(F)ccc2n1>>COC[C@H](C)N(C)Cc1cc(O)ccc1-c1cccc(-n2c(=O)n([C@H]3CC[C@@H](NCc4cn5cc(F)ccc5n4)CC3)c(=O)c3cc(F)cnc32)c1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US07060441B2,CC(=O)c1ccc(N)cc1.O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21>>CC(=O)c1ccccc1.O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21,,CN(C)C=O,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20150105317A1,[N-]=[N+]=NCCO[C@@H]1O[C@H](CO[C@H]2O[C@H](COC(=O)c3ccccc3)[C@@H](OC(=O)c3ccccc3)[C@H](OC(=O)c3ccccc3)[C@@H]2OC(=O)c2ccccc2)[C@@H](OCc2ccccc2)[C@H](O[C@H]2O[C@H](COC(=O)c3ccccc3)[C@@H](OC(=O)c3ccccc3)[C@H](OC(=O)c3ccccc3)[C@@H]2OC(=O)c2ccccc2)[C@H]1F>>[N-]=[N+]=NCCO[C@@H]1O[C@H](CO[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)[C@@H](OCc2ccccc2)[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)[C@H]1F,,CO,,CO[Na],,test
US20060100229A1,Cn1nc2c(N)nc3c(c2c1CCN)CCCC3.O=C(Cl)N1CCOCC1>>Cn1nc2c(N)nc3c(c2c1CCNC(=O)N1CCOCC1)CCCC3,,ClCCl,,CCN(CC)CC,,test
US04073892,CCOC(=O)CNCC(C)OC.COc1cc2ccc(S(=O)(=O)N[C@@H](CCCNC(=N)N)C(=O)Cl)cc2cc1OC.N#N>>CCOC(=O)CN(CC(C)OC)C(=O)[C@H](CCCNC(=N)N)NS(=O)(=O)c1ccc2cc(OC)c(OC)cc2c1.N#N,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20090018120A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.NC(=O)c1ccc2c(c1)Nc1ccccc1S2>>NC(=S)c1ccc2c(c1)Nc1ccccc1S2,,C1COCCO1,,c1ccncc1,,test
US20050256103A1,COc1cc(CO[Si](C)(C)C(C)(C)C)c([N+](=O)[O-])cc1CC1COC(C)(C)O1>>COc1cc(CO)c([N+](=O)[O-])cc1CC1COC(C)(C)O1,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150018373A1,Cc1c2cc(-n3ccc(O)cc3=O)ccc2nn1C.OCc1ccc(Br)cn1>>Cc1c2cc(-n3ccc(OCc4ccc(Br)cn4)cc3=O)ccc2nn1C,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070054960A1,CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc21.O=C(O)c1ccccc1C(=O)O>>CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc21.O=C([O-])c1ccccc1C(=O)[O-],,CCO,CCOC(C)=O,,,test
US20060235033A1,COc1cc2nccc(Oc3ccc(N)c(F)c3)c2cc1OC.C[C@@H](N)c1cccc(Br)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)N[C@H](C)c4cccc(Br)c4)c(F)c3)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US06350749B1,CC(=O)C=Cc1cc(Cl)ccc1F.CCOC(=O)CC(=O)OCC>>O=C1CC(=O)CC(c2cc(Cl)ccc2F)C1,,CCO,,C,C[O-].[Na+],test
US04882434,O=C([O-])CCC(=O)C(=O)OCc1ccc([N+](=O)[O-])cc1.Oc1ccccc1>>O=C1CCC(Oc2ccccc2)(C(=O)OCc2ccc([N+](=O)[O-])cc2)O1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04772600,CN.C[C@H](C(=O)O)n1c(-c2ccc(Cl)cc2)nc2cccnc21>>CNC(=O)[C@@H](C)n1c(-c2ccc(Cl)cc2)nc2cccnc21,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20010039285A1,COc1ccc2c(c1)CCN=C2c1ccccc1>>COc1ccc2c(c1)CCNC2c1ccccc1,,CO,,[BH4-].[Na+],,test
US04413144,CC(C)c1ccccc1.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CC(C)c1ccc(C(=O)c2ccc([N+](=O)[O-])cc2)cc1,,Clc1ccccc1,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20130331378A1,COC(=O)c1cccc(Cc2c(-c3ccccc3)nn3cc(C)ccc23)n1>>Cc1ccc2c(Cc3cccc(C(=O)O)n3)c(-c3ccccc3)nn2c1,,CO,,Cl,[K+].[OH-],test
US20110053940A1,COC(=O)CCCc1cc(Cl)c(Cl)c(CN(C(=O)[C@@H]2CN(C(=O)OC(C)(C)C)CC[C@H]2c2ccn(C)c(=O)c2)C2CC2)c1>>Cn1ccc([C@@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2C(=O)N(Cc2cc(CCCCO)cc(Cl)c2Cl)C2CC2)cc1=O,,C1CCOC1,,[BH4-].[Li+],,test
US04168964,COC(=O)NN=Cc1nc(-c2cccc(C(F)(F)F)c2)[nH]c1C>>Cc1nc(-c2cccc(C(F)(F)F)c2)n2c(=O)[nH]ncc12,,CCCCCC,,c1ccc(Oc2ccccc2)cc1,,test
US20080188521A1,N#Cc1cc(-c2ccccc2)c2ccc(C=O)cc2n1>>N#Cc1cc(-c2ccccc2)c2ccc(CO)cc2n1,,C1CCOC1,CO,[BH4-].[Na+],,test
US20070219186A1,CN(C)C=CC(=O)c1cccc(NC(=O)c2cccc(C(F)(F)F)c2)c1.CN1CCN(c2cc(N)[nH]n2)CC1>>CN1CCN(c2cc3nccc(-c4cccc(NC(=O)c5cccc(C(F)(F)F)c5)c4)n3n2)CC1,,CC(=O)O,,,,test
US04404137,BrCC1CC1.Cn1cc2c(n1)Nc1ccc(F)cc1N=C2N1CCNCC1>>Cn1cc2c(n1)Nc1ccc(F)cc1N=C2N1CCN(CC2CC2)CC1,,CC#N,,CCN(CC)CC,O,test
US06784167B2,Brc1cccs1.Cc1ccc(Br)c(F)c1>>Cc1ccc(-c2cccs2)c(F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,[Mg],,test
US05081246,CI.O=S(=O)(NC(Cc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1)CN1CCN(c2ccccc2)CC1)c1cccc2cnccc12>>CN(C(Cc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1)CN1CCN(c2ccccc2)CC1)S(=O)(=O)c1cccc2cnccc12,,CN(C)C=O,,[H-].[Na+],,test
US20130059853A1,COc1c(OC(F)F)ccc(-c2cccc3c2CCC3=O)c1O.CS(=O)(=O)c1ccc(CBr)cc1>>COc1c(OC(F)F)ccc(-c2cccc3c2CCC3=O)c1OCc1ccc(S(C)(=O)=O)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080027084A1,CC(=O)N[C@@H]1C[C@H](NC(C)(C)C)CC[C@@H]1N1CC[C@H](NC(=O)OCc2ccccc2)C1=O>>CC(=O)N[C@@H]1C[C@H](NC(C)(C)C)CC[C@@H]1N1CC[C@H](N)C1=O,[Pd],CO,,,,test
US20040209901A1,COC(=O)CNc1nc(-c2ccc(F)cc2C)c2ccc(=O)n(-c3c(F)cccc3F)c2n1.N>>Cc1cc(F)ccc1-c1nc(NCC(N)=O)nc2c1ccc(=O)n2-c1c(F)cccc1F,,CCOC(C)=O,ClCCl,C[Al](C)C,,test
US20030158179A1,CCOC(=O)c1c[nH]c2cc(I)c(C)cc2c1=O>>Cc1cc2c(=O)c(C(=O)O)c[nH]c2cc1I,,[Na+],[OH-],Cl,,test
US20070037794A1,Cc1ccc(S(=O)(=O)Nc2cc(Cl)cnc2C(O)c2ccnc(NCCO[Si](C)(C)C(C)(C)C)c2)cc1C(F)(F)F>>Cc1c(C(F)(F)F)cccc1S(=O)(=O)Nc1cc(Cl)cnc1C(=O)c1ccnc(NCCO)c1,O=[Mn]=O,,,C1COCCO1,,test
US08524914B2,CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1C=O.CC(Cc1ccccc1)C(C)(C(=O)[O-])[C@H]1C[C@@H](CS(=O)(=O)c2nnnn2-c2ccccc2)OC(C)(C)O1>>CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1/C=C/[C@@H]1C[C@H](CC(=O)OC(C)(C)Cc2ccccc2)OC(C)(C)O1,,C1CCOC1,CCOC(C)=O,[Cl-].[NH4+],C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20120202687A1,CC(=O)CCl.CCC(C)=O.Cc1ccccc1NC(=S)N/N=C/c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1>>Cc1cccc(C)c1-n1c(C)cs/c1=N/N=C\c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1,,CCC(C)=O,,CCN(CC)CC,O,test
US20110189192A1,COC(=O)C1(OC)CCN(C(=O)OCc2ccccc2)C1>>COC(=O)C1(OC)CCNC1,[Pd],CO,,,,test
US20140323468A1,CC(C)(C)OC(=O)n1c(-c2cncc(Br)c2)cc2ccccc21>>Brc1cncc(-c2cc3ccccc3[nH]2)c1,,CCOC(C)=O,,Cl,,test
US20110190297A1,NC(=O)C1CCN(c2nc(Cl)ncc2-c2ccccc2)CC1>>NC(=O)C1CCN(c2ncncc2-c2ccccc2)CC1,[Pd],CC(=O)O,,CC(=O)[O-].[K+],,test
US20110275608A1,CC(C)(C)OC(=O)NCC1CCNCC1.O=S(=O)(Cl)c1ccc(-c2ccccn2)s1>>CC(C)(C)OC(=O)NCC1CCN(S(=O)(=O)c2ccc(-c3ccccn3)s2)CC1,,ClCCl,,CCN(CC)CC,,test
US05204350,CC(C)(C)OC(=O)NCCCCCCCCBr.CCOC(C)=O.ClCCl.O>>O=C(N[C@@H](Cc1ccc(O)cc1)C(=O)O)OCc1ccccc1,,CCOC(C)=O,ClCCl,[H-].[Na+],,test
US20160130254A1,CCI.N#Cc1ccc(NC2CCC(n3cnc4ccccc43)C2)cc1C(F)(F)F>>CCN(c1ccc(C#N)c(C(F)(F)F)c1)C1CCC(n2cnc3ccccc32)C1,,CN(C)C=O,,[H-].[Na+],,test
US20020040146A1,COc1ccc(CS[C@@H]2C[C@@H](CNCc3cc(F)ccc3F)N(C(=O)OC(C)(C)C)C2)cc1.O=C(Cl)OCC1c2ccccc2-c2ccccc21>>COc1ccc(CS[C@@H]2C[C@@H](CN(Cc3cc(F)ccc3F)C(=O)OCC3c4ccccc4-c4ccccc43)N(C(=O)OC(C)(C)C)C2)cc1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20110009454A1,C#CCCCCl.Nc1ncccc1C(=O)NCc1ccc(O)cc1>>C#CCCCOc1ccc(CNC(=O)c2cccnc2N)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20090318690A1,CCOC(CSc1ccccc1C(=O)OC)OCC>>COC(=O)c1cccc2ccsc12,,Clc1ccccc1,,,,test
US20110301161A1,CC(C)(C)n1c(-c2ccccc2C(=O)NN)nc2cc(-c3cnc(N)nc3)ccc21.N#CBr>>CC(C)(C)n1c(-c2ccccc2-c2nnc(N)o2)nc2cc(-c3cnc(N)nc3)ccc21,,C1COCCO1,O,O=C([O-])O.[Na+],,test
US20120245176A1,CC(=O)Cl.COc1ccc(N)cc1-c1noc(C)c1C(=O)N1CCN(c2ncc(Cl)cc2Cl)CC1>>COc1ccc(NC(C)=O)cc1-c1noc(C)c1C(=O)N1CCN(c2ncc(Cl)cc2Cl)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160194284A1,Nc1ccc(F)cc1.O=C(Nc1ccc(Cl)cc1)Nc1cccc(-c2cccc(N3CCCC3)n2)c1>>O=C(Nc1ccc(F)cc1)Nc1cccc(-c2cccc(N3CCCC3)n2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US03983129,COc1nsc(-c2ccccc2)c1C#N>>N#Cc1c(O)nsc1-c1ccccc1,,CC(=O)O,,Br,,test
US20160096827A1,COc1cc(Nc2ncnc(-c3ccc(O[C@H]4CCNCC4(F)F)c(C#N)c3)n2)ccc1N1CCN(C2COC2)CC1.O=C(O)CO>>COc1cc(Nc2ncnc(-c3ccc(O[C@H]4CCN(C(=O)CO)CC4(F)F)c(C#N)c3)n2)ccc1N1CCN(C2COC2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04727067,NC(=O)c1cc(OCCN(Cc2ccccc2)CC(O)COc2ccc(OCCO)cc2)ccc1O>>NC(=O)c1cc(OCCNCC(O)COc2ccc(OCCO)cc2)ccc1O,[Pd],CO,,[H][H],,test
US20100048573A1,CC(=O)Nc1ccc(S(=O)(=O)Nc2ccccc2)cc1>>Nc1ccc(S(=O)(=O)Nc2ccccc2)cc1,,CCO,,Cl,,test
US20150291595A1,COc1ccc(S(=O)(=O)Nc2cncc(Br)c2)c(F)c1>>O=S(=O)(Nc1cncc(Br)c1)c1ccc(O)cc1F,,ClCCl,,BrB(Br)Br,CO,test
US20080132539A1,CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1.CC(C)(C)c1ccc(CBr)cc1>>CC(C)(C)OC(=O)NC(Cc1cn(Cc2ccc(C(C)(C)C)cc2)c2ccccc12)C(=O)OCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US05187185,Cc1cc(SC(F)(Cl)Cl)c(C)n1-c1c(Cl)cc(C(F)(F)F)cc1Cl.O=C=NS(=O)(=O)Cl>>Cc1c(C#N)c(SC(F)(Cl)Cl)c(C)n1-c1c(Cl)cc(C(F)(F)F)cc1Cl,,CC#N,ClCCl,CN(C)C=O,,test
US20060047171A1,CCOP(=O)(CC#N)OCC.Cc1ccc(C=O)cc1C>>Cc1ccc(C=CC#N)cc1C,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20120136023A1,CCOC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1)CCOC3>>Cc1ccc(-c2c(C(OC(C)(C)C)C(=O)O)c(C)nc3sc4c(c23)CCOC4)cc1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20160228441A1,O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC(O)C1.O[C@H]1CCNC1>>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC[C@@H](O)C1,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20120059173A1,CC(C)(Br)C(=O)Br.OCCCO>>CC(C)(Br)C(=O)OCCCO,,C1CCOC1,,CCN(CC)CC,,test
US20070093521A1,O=[N+]([O-])c1cccc(S(=O)(=O)N2CCCC2)c1O>>Nc1cccc(S(=O)(=O)N2CCCC2)c1O,[Pd],C1CCOC1,,,,test
US06008213,CCCC[Sn](C#CCCOC1CCCCO1)(CCCC)CCCC.CCOC(=O)CC1Cc2ccc(OS(=O)(=O)C(F)(F)F)cc2Cc2ccccc21>>CCOC(=O)CC1=Cc2ccc(C#CCCOC3CCCCO3)cc2Cc2ccccc21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,[Cl-].[Li+],,test
US20050261294A1,COC(=O)c1cccc(CN(c2nccc(-c3ccc(O)cc3)n2)C2CCCC2)c1.C[C@@H]1CC[C@@H](O)CC1>>COC(=O)c1cccc(CN(c2nccc(-c3ccc(O[C@@H]4CC[C@H](C)CC4)cc3)n2)C2CCCC2)c1,,C1CCOC1,O,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090227588A1,O=C(Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)nc1)c1cccc(Br)c1.OB(O)N1C=CC=NC1>>O=C(Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)nc1)c1cccc(-c2cncnc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130338150A1,CC(C)(C)NS(=O)(=O)CC(=O)c1ccc(F)cc1.[NH4+]>>CC(C)(C)NS(=O)(=O)CC(N)c1ccc(F)cc1,,CO,,[BH3-]C#N.[Na+],,test
US20160222033A1,CC(=O)c1c(C)sc2nc(Cn3ccc(C(F)(F)F)n3)cc(=O)n12>>Cc1sc2nc(Cn3ccc(C(F)(F)F)n3)cc(=O)n2c1C(C)O,,CO,,[Na],,test
US20110015175A1,COc1cc([N+](=O)[O-])c(F)cc1-n1cnc(C)n1>>COc1cc(N)c(F)cc1-n1cnc(C)n1,[Pd],CO,,,,test
US20110070190A1,COC(=O)c1sc(-c2ccc(CO)cc2)cc1NCc1ccc(C)cc1.NC=O>>Cc1ccc(Cn2cnc(=O)c3sc(-c4ccc(CO)cc4)cc32)cc1,,CN(C)C=O,,C[O-].[Na+],,test
US20130096118A1,C1CCOC1.CCOC(=O)c1cc2c(cn1)[nH]c1c(C(N)=O)ccc(Br)c12>>CC(C)(O)c1cc2c(cn1)[nH]c1c(C(N)=O)ccc(Br)c12,,CCOCC,,Cl,O=C([O-])O.[Na+],test
US04012374,C1=C(c2ccccc2)CCNC1.Cl.O=C1CCCC(=O)N1CCCCBr>>Cl.O=C1CCCC(=O)N1CCCCN1CC=C(c2ccccc2)CC1,,Cc1ccccc1,,O,O=C([O-])[O-].[Na+].[Na+],test
US05254595,CCOC(=O)c1cc2c(OCC(O)CNC3CCc4ccccc4C3)cccc2[nH]1>>NC1CCc2ccccc2C1,,CCO,,Cl,,test
US20040147525A1,C(=NC1CCN2CCCC2C1)c1ccncc1.[C-]#[N+]C(c1ccc(F)cc1)S(=O)(=O)c1ccc(C)cc1>>Fc1ccc(-c2ncn(C3CCN4CCCC4C3)c2-c2ccncc2)cc1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20150080392A1,CCCN.O=Cc1ccc(-c2ccc3ncnc(Nc4ccc(F)c(Cl)c4)c3c2)o1>>CCCNCc1ccc(-c2ccc3ncnc(Nc4ccc(F)c(Cl)c4)c3c2)o1,,C1CCOC1,CN(C)C=O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05324747,CCCCCCCCCCCCCCCCCCOc1cc(N(CC(=O)OC)CC(=O)OC)cc(S(C)=O)c1>>CCCCCCCCCCCCCCCCCCOc1cc(N(CC(=O)O)CC(=O)O)cc(S(C)=O)c1,,CO,,[Na+].[OH-],,test
US20070244159A1,CC(C)(C)OC(=O)OC(C)(C)C.CCOC(=O)Cc1cc2ccccc2[nH]1>>CCOC(=O)Cc1cc2ccccc2n1C(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,,,test
US04476307,CCCCCC.CCOCC.CN(C)C=C1C(=O)Nc2ccccc21>>COc1cccc(N2C(=O)C(=CN(C)C)c3ccccc32)c1,,CCCCCC,CN(C)C=O,[H-].[Na+],,test
US20040248951A1,COc1c([N+](=O)[O-])cccc1C(F)(F)F>>O=[N+]([O-])c1ccc(O)c(C(F)(F)F)c1,,Br,,CC(=O)O,,test
US20090163512A1,CCC(CC)(Oc1ccc(Cl)cc1C=O)C(=O)OC.O=C1Cc2cc(F)c(Cl)cc2N1>>CCC(CC)(Oc1ccc(Cl)cc1/C=C1\C(=O)Nc2cc(Cl)c(F)cc21)C(=O)OC,,CO,,C1CCNC1,,test
US20090054411A1,CCOC=C(C(=O)OCC)C(=O)OCC.Nc1ccc(N2CCOCC2)cc1>>CCOC(=O)C(=CNc1ccc(N2CCOCC2)cc1)C(=O)OCC,,CC#N,,CCOC(C)=O,,test
US04369184,CCOC(=O)C1(c2ccccc2)CCNCC1.N#CC1(c2ccccn2)CCC(=O)CC1>>CCOC(=O)C1(c2ccccc2)CCN(C2=CCC(C#N)(c3ccccn3)CC2)CC1,,O,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US04215123,CCn1c(=O)c(C#N)c(N2CCCC2)c2ccc(C)nc21.[OH-]>>CCn1c(=O)c(C#N)c(O)c2ccc(C)nc21,,CCO,,Cl,,test
US04680300,Clc1ccc2c(CCCCCCNC(=Nc3ccccc3)Nc3ccccc3)ccnc2c1>>Clc1ccc2c(CCCCCCNC(=Nc3ccccc3)Nc3ccccc3)ccnc2c1,,O,,Cl,[Na+].[OH-],test
US20100144714A1,CC(C)CC1C(=O)N(Cc2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)cc2)c2nc3ccccc3c(=O)n21.Cl>>CC(C)CC1C(=O)N(Cc2ccc(N3CCNCC3)cc2)c2nc3ccccc3c(=O)n21.Cl,,C1COCCO1,,,,test
US20160272617A1,CCN(CC)CCCNC(=O)c1ccc(-c2ccc(C[C@H](NC(=O)[C@@H]3CC[C@@H](CNC(=O)OC(C)(C)C)CC3)C(=O)Nc3ccc(-c4nn[nH]n4)cc3)cc2)c(C)c1.Cl>>CCN(CC)CCCNC(=O)c1ccc(-c2ccc(C[C@H](NC(=O)[C@@H]3CC[C@@H](CN)CC3)C(=O)Nc3ccc(-c4nn[nH]n4)cc3)cc2)c(C)c1.Cl,,C1COCCO1,,O=C(O)C(F)(F)F,,test
US20120225863A1,COC(=O)c1ccc2[nH]c(=O)c(Cl)nc2c1.C[C@@H]1CCCN1>>COC(=O)c1ccc2[nH]c(=O)c(N3CCC[C@H]3C)nc2c1,,CS(C)=O,,CCN(C(C)C)C(C)C,Cl,test
US20050004382A1,CC(C)CCC[C@@H](C)[C@H]1CC[C@@H]2[C@]1(C)CC[C@@]13O[C@@]21CC=C1C[C@H](O)CC[C@@]13C>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3(O)CC[C@]12C,,CCNCC,,[Li],,test
US05965575,COC(=O)CC(=O)CCl.COc1cc2c(cc1OC)C(C)=NCC2>>COC(=O)Cc1cc2n(c1)CCc1cc(OC)c(OC)cc1-2,,CCO,,O=C([O-])O.[Na+],,test
US20050256203A1,CN(C)CC1CCCCC1(O)c1cccc(C(N)=O)c1>>CN(C)C[C@H]1CCCC[C@]1(O)c1cccc(C(N)=O)c1,,CC#N,,,,test
US03954764,Cc1ccc2c(c1)CC(N1CCNCC1)c1cc(Cl)ccc1S2.O=C1CCCN1CCCl>>Cc1ccc2c(c1)CC(N1CCN(CCN3CCCC3=O)CC1)c1cc(Cl)ccc1S2,,Cc1ccccc1,,[I-].[K+],O=C([O-])O.[Na+],test
US20140275065A1,CC(C)(C)OC(=O)N1C2CCC1C(CN=[N+]=[N-])C2>>[N-]=[N+]=NCC1CC2CCC1N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130158030A1,CCN1CCNCC1.Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1NC(=O)CCBr>>CCN1CCN(CCC(=O)Nc2c(C)[nH]c(/C=C3\C(=O)Nc4ccc(F)cc43)c2C)CC1,,CN(C)C=O,,CCOC(C)=O,,test
US04428949,CC(CF)(CF)C(=O)C(Br)Oc1cccc(C(F)(F)F)c1.c1c[nH]cn1>>CC(CF)(CF)C(=O)C(Oc1cccc(C(F)(F)F)c1)n1ccnc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130045169A1,BrCCCC1OCCO1.O=C(O)c1ccc(CO)cc1>>O=C(OCCCC1OCCO1)c1ccc(CO)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20070010402A1,Cc1cc(C(N)=O)c(N)s1.O=C(Cl)CCC(F)(F)F>>Cc1cc(C(N)=O)c(NC(=O)CCC(F)(F)F)s1,,O,,CCN(CC)CC,CCOC(C)=O,test
US20110207698A1,ClCc1csc(-c2ccc(Cl)cc2)n1.N#Cc1c(N)nc(S)c(C#N)c1-c1cccs1>>N#Cc1c(N)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1cccs1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20080085890A1,COc1ccc(C(C)N=[N+]=[N-])cc1OCc1ccccc1>>COc1ccc(C(C)N)cc1O,[Pd],Cl,,,,test
US20090137595A1,CCOC(=O)c1cc(C)nn1CC(F)(F)F>>Cc1cc(C(=O)O)n(CC(F)(F)F)n1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20100249123A1,CC(C)(C#N)c1ccc(N)cc1-c1ccsc1.COc1ccc(C(=O)Cl)cc1OC>>COc1ccc(C(=O)Nc2ccc(C(C)(C)C#N)c(-c3ccsc3)c2)cc1OC,,ClCCl,,CCN(CC)CC,,test
US06235771B1,CCCOCCOc1ccc2cc(OB([O-])[O-])oc2c1.CN(Cc1ccc(NC(=O)C2=Cc3cc(Br)ccc3S(=O)(=O)CC2)cc1)C1CCOCC1>>CCCOCCOc1ccc2cc(-c3ccc4c(c3)C=C(C(=O)Nc3ccc(CN(C)C5CCOCC5)cc3)CCS4(=O)=O)oc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[K+].[K+],test
US04992435,BrBr.CC1(C)Oc2ccsc2C(N2CCCC2=O)C1O>>CC1(C)Oc2cc(Br)sc2C(N2CCCC2=O)C1O,,ClCCl,,,,test
US20100113510A1,BrCCCOc1ccccc1.C[C@](C(=O)O[C@H]1CN2CCC1CC2)(c1ccccc1)N1CCCCC1>>C[C@](C(=O)O[C@H]1C[N+]2(CCCOc3ccccc3)CCC1CC2)(c1ccccc1)N1CCCCC1.[Br-],,CC#N,,CCOCC,,test
US04931083,CC(Oc1ncn(-c2cccc(C(F)(F)F)c2)n1)C(=O)O.CNC>>CC(Oc1ncn(-c2cccc(C(F)(F)F)c2)n1)C(=O)N(C)C,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20160185777A1,O=C(O)c1n[nH]c2c1CN(C(=O)Nc1cccc(Cl)c1)CC2.OC1CNOC1>>O=C(Nc1cccc(Cl)c1)N1CCc2[nH]nc(C(=O)N3CC(O)CO3)c2C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04237136,CCCCOC(=O)C#CC(=O)OCCCC.Nc1nc(-c2ccccc2)cs1>>CCCCOC(=O)c1cc(=O)nc2scc(-c3ccccc3)n12,,CCO,,,,test
US20080221090A1,CC(C)(C)[Si](C)(C)OCCBr.COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccc(OC)cc3)[nH]c2c1Cl>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccc(OC)cc3)n(CCO[Si](C)(C)C(C)(C)C)c2c1Cl,,CS(C)=O,O,Cl,[H-].[Na+],test
US20130197217A1,CCCC[Sn](/C=C\OCC)(CCCC)CCCC.Clc1ncc(Br)cn1>>CCO/C=C\c1cnc(Cl)nc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,,,,test
US04033756,NC1CC1.O=C(Cl)C(Cl)Cl>>O=C(NC1CC1)C(Cl)Cl,,c1ccccc1,,CCN(CC)CC,,test
US20110306587A1,FC(F)(F)CI.O=C(c1nc2ccccc2[nH]1)N1CC(c2nccnc2Cl)C1>>O=C(c1nc2ccccc2n1CC(F)(F)F)N1CC(c2nccnc2Cl)C1,,CN(C)C=O,,[H-].[Na+],,test
US05510362,CI.O=[N+]([O-])c1ccc(Cc2nnn[nH]2)cc1>>Cn1nnnc1Cc1ccc([N+](=O)[O-])cc1,,CC#N,,CCN(CC)CC,,test
US05516774,Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1.O=C(Cl)c1sc2ccccc2c1Cl>>O=C(Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1)c1sc2ccccc2c1Cl,,ClCCl,,CCN(CC)CC,,test
US04808729,CCCc1c(OCCCSCC2COC(CCC(=O)O)(CCC(=O)O)S2)ccc(C(C)=O)c1O.O=C(OO)c1cccc(Cl)c1>>CCCc1c(OCCCS(=O)CC2COC(CCC(=O)O)(CCC(=O)O)S2)ccc(C(C)=O)c1O,,ClCCl,,,,test
US20140309225A1,CC(C)C(OC(=O)c1ccc([N+](=O)[O-])cc1)[C@H](C)NC(=O)OC(C)(C)C>>CC(C)C(O)[C@H](C)NC(=O)OC(C)(C)C,,CO,,[Li+].[OH-],,test
US20100130492A1,CN(C)CCN.Cc1nc(N)ncc1-c1nc(N2CCOCC2)c2nc(Cl)n(CC3CC3)c2n1>>Cc1nc(N)ncc1-c1nc(N2CCOCC2)c2nc(NCCN(C)C)n(CC3CC3)c2n1,,CS(C)=O,,,,test
US20100174065A1,CCOC(=O)CCCCN1CCOc2c(cccc2-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)C1>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3OCCN(CCCCC(=O)O)C4)no2)cc1C#N,,CCO,,[Na+].[OH-],,test
US08471005B2,COc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1ncc2ccc(-c3cccc(S(=O)(=O)NC(C)(C)C)c3)n2n1>>COc1cc(C2CCNCC2)ccc1Nc1ncc2ccc(-c3cccc(S(=O)(=O)NC(C)(C)C)c3)n2n1,,ClCCl,,CCOC(C)=O,Cl,test
US20110201608A1,N.O=C(O)C1CCN(c2nc(-c3ccc(N4CCOCC4)cc3)cc3ncccc23)C1>>NC(=O)C1CCN(c2nc(-c3ccc(N4CCOCC4)cc3)cc3ncccc23)C1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20070299056A1,COc1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)cn1>>O=c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)c[nH]1,,CCO,Cl,,,test
US20140296205A1,CC(O)[C@H]1O[C@@H]2SC(N(C)C(=O)OC(C)(C)C)=N[C@@H]2C[C@@H]1OCc1ccccc1>>CC(=O)[C@H]1O[C@@H]2SC(N(C)C(=O)OC(C)(C)C)=N[C@@H]2C[C@@H]1OCc1ccccc1,,ClCCl,,,,test
US05411981,CC(C)(O)C#N.NCCCCO>>CC(C)(C#N)NCCCCO,,ClCCl,,,,test
US07259262B2,COc1ccc(-c2nc(Cn3ccnc3)cs2)cc1>>Oc1ccc(-c2nc(Cn3ccnc3)cs2)cc1,,Br,,N,,test
US20100278833A1,COC(=O)c1sc(-n2cnc3ccncc32)cc1O.FC(F)(F)c1cccc(CBr)c1>>COC(=O)c1sc(-n2cnc3ccncc32)cc1OCc1cccc(C(F)(F)F)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US09409895B2,NCCCN1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1.O=C(O)c1c[nH]nn1>>O=C(NCCCN1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1)c1c[nH]nn1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150025087A1,Cc1c(CO)ncnc1OC(F)F.O=S(Cl)Cl>>Cc1c(CCl)ncnc1OC(F)F,,ClCCl,,,,test
US20140350019A1,CC(C)O.O=C(O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1F>>CC(C)OC(=O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1F,O=S(=O)(O)O,,,,,test
US20130053366A1,C=CCN1CCc2[nH]c3ccc(C)cc3c2C1.c1cc(C2CO2)ccn1>>C=CCN1CCc2c(c3cc(C)ccc3n2CC(O)c2ccncc2)C1,,CN(C)C=O,,[H-].[Na+],,test
US20080262041A1,C=O.CC(c1cc(Cl)cc(Cl)c1)N1CCC(C2(c3ccc(F)cc3)CCNCC2)C1=O>>CC(c1cc(Cl)cc(Cl)c1)N1CCC(C2(c3ccc(F)cc3)CCN(C)CC2)C1=O,,CC#N,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05760054,O=C1c2cccnc2S(=O)(=O)N1CCCCO.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>O=C1c2cccnc2S(=O)(=O)N1CCCCOS(=O)(=O)c1ccc([N+](=O)[O-])cc1,,C1CCOC1,,CCN(CC)CC,,test
US20030229102A1,O=C(NCCc1cccc2c(CCNC(=O)OCc3ccccc3)cccc12)OCc1ccccc1>>NCCc1cccc2c(CCN)cccc12,[Pd],,,,,test
US05599814,Cc1cc(C)cc(NC(=O)C=NO)c1>>Cc1cc(C)c2c(c1)NC(=O)C2=O,,O,,O=S(=O)(O)O,,test
US05821239,CN(C)C=Nc1ccncc1O.CN=C=O>>CNC(=O)Oc1cnccc1N=CN(C)C,,C1CCOC1,,[H-].[Na+],,test
US20020133007A1,Cc1c(Cl)cc(F)c(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c1[N+](=O)[O-]>>Cc1c(Cl)cc(F)c(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c1N,[Fe],CC(=O)O,,O,,test
US06329389B1,CN(C)CC1Cc2ccccc2N(C(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)OCC2c3ccccc3-c3ccccc32)C1>>CN(C)CC1Cc2ccccc2N(C(=O)[C@H](N)Cc2c[nH]c3ccccc23)C1,,CO,,C1CCNCC1,,test
US20030158197A1,Cc1cc(C)c(-n2cnc3c(N)cc(C)nc32)c(C)c1.O=C(Cl)CCl>>Cc1cc(C)c(-n2cnc3c(NC(=O)CCl)cc(C)nc32)c(C)c1,,ClCCCl,,CCN(C(C)C)C(C)C,O=C([O-])[O-].[K+].[K+],test
US05594023,Cl[Mg]Cc1ccccc1.O=C1Nc2ccc(Cl)cc2C1=O>>O=C1Nc2ccc(Cl)cc2C1(O)Cc1ccccc1,,C1CCOC1,CCOCC,[Cl-].[NH4+],,test
US20080193381A1,CC(C)(C)OC(=O)CCC(NC(=O)NC(CCCCN)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.C[Sn](C)(C)c1ccc(C=O)cc1>>CC(C)(C)OC(=O)CCC(NC(=O)NC(CCCCNCc1ccc([Sn](C)(C)C)cc1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070129443A1,ClCBr.O=C(OCc1ccccc1)[C@H](Cc1ccccc1)N(Cc1ccccc1)Cc1ccccc1>>O=C(CCl)[C@H](Cc1ccccc1)N(Cc1ccccc1)Cc1ccccc1,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US20040198756A1,CCOC(=O)CSc1cc(F)ccc1[N+](=O)[O-]>>O=C1CSc2cc(F)ccc2N1,[Fe],CC(=O)O,,,,test
US20060211697A1,COC(=O)[C@@H](N)CS.Cc1ccc(Oc2ccc(C=O)cc2)c(O)c1>>COC(=O)C1CSC(c2ccc(Oc3ccc(C)cc3O)cc2)N1,,ClCCl,,CCN(CC)CC,Cl,test
US20030232863A1,CC(=O)N[C@@H](CC(C)C(F)(F)F)C(=O)O>>CC(=O)N[C@H](CC(C)C(F)(F)F)C(=O)O,,O,,[Na+].[OH-],,test
US20140323435A1,O=P(Cl)(Cl)Cl.Oc1nc(-c2ccncc2)nc2c(Cl)csc12>>Clc1csc2c(Cl)nc(-c3ccncc3)nc12,,CN(C)C=O,,,,test
US20100022515A1,CC(C)OC(=O)N1CCC(CCOc2ccc3c(c2)CCN(C(=O)OCc2ccccc2)C3)CC1>>CC(C)OC(=O)N1CCC(CCOc2ccc3c(c2)CCNC3)CC1,[Pd],CO,,,,test
US20030069233A1,COc1ccc([N+](=O)[O-])cc1OC1CCN(C)C1>>COc1ccc(N)cc1OC1CCN(C)C1,[Pd],CCO,,,,test
US20090181942A1,COC(=O)C=Cc1cccn1-c1ccc(Cl)cc1C(O)c1cccc(OC)c1>>COc1cccc(C(O)c2cc(Cl)ccc2-n2cccc2C=CC(=O)O)c1,,CO,,O,O=C([O-])[O-].[K+].[K+],test
US20130116204A1,CCOc1cc([C@@H](CS(C)(=O)=O)N2Cc3cccc(N)c3C2=O)ccc1OC.O=C(Cl)C1CC1>>CS(=O)(=O)C[C@H](c1ccc(O)c(O)c1)N1Cc2cccc(NC(=O)C3CC3)c2C1=O,,C1CCOC1,,C[Si](C)(C)I,,test
US20070082912A1,CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(C(F)(F)F)ccc2OCc2ccc(OC)cc2)c1>>COc1ccc(COc2ccc(C(F)(F)F)cc2-c2ccc(C)n2-c2cccc(C(=O)O)c2)cc1,,CCOC(C)=O,,CCO,[Na+].[OH-],test
US20050065151A1,CO.Nc1cc(N2CCOCC2)ncc1I>>COc1cnc(N2CCOCC2)cc1N,[Cu]I,CO,,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US20140038923A1,CCOC(=O)CCc1cc(-c2ccccc2)n(-c2ccc(S(C)(=O)=O)cc2)n1>>CS(=O)(=O)c1ccc(-n2nc(CCCO)cc2-c2ccccc2)cc1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20040192686A1,CC1CCCC(C)N1CCN.Cc1cccc2nc(Cl)n[n+]([O-])c12>>Cc1cccc2nc(NCCN3C(C)CCCC3C)n[n+]([O-])c12,,COCCOC,,,,test
US20050245563A1,CC(C)(C)OC(=O)NCCCCO.O=c1[nH]c2ccc(Br)cc2c(=O)o1>>CC(C)(C)OC(=O)NCCCCn1c(=O)oc(=O)c2cc(Br)ccc21,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140038943A1,O=S(Cl)Cl.OCc1cc(Br)ccc1OCc1cccc(Cl)c1>>ClCc1cc(Br)ccc1OCc1cccc(Cl)c1,,ClCCl,,,,test
US20160009744A1,Cc1sc(C=O)cc1CO[Si](C)(C)C(C)(C)C>>Cc1sc(C=O)cc1CO,,C1CCOC1,,,,test
US20040110749A1,CC(C)(C)n1nc(C(F)(F)F)cc1O.CN(C)C=O.O=P(Cl)(Cl)Cl>>CC(C)(C)n1nc(C(F)(F)F)c(C=O)c1Cl,,O,,,,test
US20130102609A1,CC(C)(C)OC(=O)COc1ccc(CN)cc1Br.O=S(=O)(Cl)c1ccc(F)cc1>>CC(C)(C)OC(=O)COc1ccc(CNS(=O)(=O)c2ccc(F)cc2)cc1Br,,ClCCl,,CCN(CC)CC,,test
US20160075653A1,NO.O=C1CCC1c1c(F)cccc1F>>ON=C1CCC1c1c(F)cccc1F,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US05965741,COC(=O)c1ccc(CBr)cc1.Oc1c(Br)cccc1Cc1ccccc1>>COC(=O)c1ccc(COc2c(Br)cccc2Cc2ccccc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070244136A1,CNCCOc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12.COC(=O)Cl>>COC(=O)N(C)CCOc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05672588,C[C@H](COc1ccccc1)NC(=O)OC(C)(C)C.Cl>>C[C@@H](N)COc1ccccc1.Cl,,CCOC(C)=O,,,,test
US20110122475A1,CCCCCCCCCCCCI.Oc1ccc(-c2ccc(Br)cc2)cc1>>CCCCCCCCCCCCOc1ccc(-c2ccc(Br)cc2)cc1,,CCC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20020193389A1,C1COCCN1.N#Cc1cccc(F)c1>>N#Cc1cccc(N2CCOCC2)c1,,CC#N,,,,test
US04367089,CC(C)(C)C(=O)C(Oc1ccc(Cl)cc1)n1cncn1.O=C(Cl)Cl>>CC(C)(C)C(OC(=O)Cl)=C(Oc1ccc(Cl)cc1)n1cncn1,,C1CCOC1,,c1ccncc1,,test
US20020183327A1,CC=O.Nc1ncccc1OCc1ccccc1.[C-]#[N+]C(C)(C)CC(C)(C)C>>Cc1nc2c(OCc3ccccc3)cccn2c1NC(C)(C)CC(C)(C)C,,[O-][Cl+3]([O-])([O-])O,,,,test
US20080076924A1,C1CCNC1.CC(C)C1CN(c2ccc(Cl)nn2)CCN1.[C]=O>>CC(C)C1CN(c2ccc(C(=O)N3CCCC3)nn2)CCN1,,CN(C)C=O,,CCN(CC)CC,ClCCl,test
US20070259846A1,CCOC(=O)c1ccc(N2CCN(c3nc4c(c(NC5CCCCC5)n3)SCC4)CC2)cc1.Clc1nc(N2CCN(c3ccccc3)CC2)nc2c1SCC2>>NCCCc1nc(N2CCNCC2)nc2c1SCC2,,C1COCCO1,,,,test
US04870096,COC(=O)CCc1ccc2[nH]cc(CCN(C)C)c2c1>>CN(C)CCc1c[nH]c2ccc(CCC(=O)O)cc12,,CO,,O,[Li+].[OH-],test
US04490374,CI.COc1ccc([N+](=O)[O-])c(C=O)c1O>>COc1ccc([N+](=O)[O-])c(C=O)c1OC,,CN(C)C=O,CN(C)C=O,[H-].[Na+],,test
US20120245161A1,Cc1cccc2cc[nH]c12.O=C(Cl)C(Cl)(Cl)Cl>>Cc1cccc2c(C(=O)C(Cl)(Cl)Cl)c[nH]c12,,C1CCOC1,,CCOC(C)=O,c1ccncc1,test
US20020065308A1,CC(C)(C)[Si](C)(C)Cl.O=C1CCC(CCC(O)Cc2ccccc2)N1>>CC(C)(C)[Si](C)(C)OC(CCC1CCC(=O)N1)Cc1ccccc1,CN(C)c1ccncc1,CN(C)C=O,,c1c[nH]cn1,,test
US20120071461A1,CN(C(=O)OC(C)(C)C)C1CCNCC1.O=Cc1ccnc(N2CCCC2)c1>>CN(C(=O)OC(C)(C)C)C1CCN(Cc2ccnc(N3CCCC3)c2)CC1,,ClCCl,,CC(=O)O,O=C([O-])O.[Na+],test
US20140088121A1,CC(C)(C)S(=O)Cl.CCN(CC)CC.[Br-]>>CC(C)(C)S(=O)NCCBr,,ClCCl,,,,test
US20120142717A1,CI.COc1ncc(Cc2c[nH]c(=S)[nH]c2=O)cn1>>COc1ncc(Cc2c[nH]c(SC)nc2=O)cn1,,CCO,,C,C[O-].[Na+],test
US05550121,CC(C)(C)OC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]1[C@@H](O)CCO.CC(C)(C)[Si](C)(C)Cl>>CC(C)(C)OC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]1[C@@H](O)CCO[Si](C)(C)C(C)(C)C,,ClCCl,,O,c1c[nH]cn1,test
US20090156812A1,O=C(O)c1cc(=O)[nH]c(=O)[nH]1.O=S(Br)Br>>O=C(Br)c1cc(=O)[nH]c(=O)[nH]1,,O,,,,test
US06087380,CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(COc1ccc(C(=N)N)cc1)n2C)c1ccccc1.Cl>>Cl.Cn1c(COc2ccc(C(=N)N)cc2)nc2cc(C(=O)N(CCC(=O)O)c3ccccc3)ccc21,,CCO,ClCCl,[Na+].[OH-],,test
US20100291151A1,CCOC(=O)CBr.Cn1nccc1C(O)c1ccccc1>>CCOC(=O)COC(c1ccccc1)c1ccnn1C,,C1CCOC1,,CCOC(C)=O,[H-].[Na+],test
US04391816,COc1ccc(C(=O)O)c2cccc(S(=O)(=O)N(C)C)c12.O=S(=O)(Cl)Cl>>COc1c(Cl)cc(C(=O)O)c2cccc(S(=O)(=O)N(C)C)c12,,CC(=O)O,,,,test
US20110092612A1,C=C(C)C(=O)Cl.Oc1cccc(-c2cccc3c2sc2ccccc23)c1>>C=C(C)C(=O)Oc1ccccc1-c1cccc2c1sc1ccccc12,,ClCCl,,CCN(CC)CC,O,test
US20110269712A1,CCOC(=O)C1(N2CCCCC2)C=NNN1.Cc1cc(C(F)(F)F)nn1CC(=O)O>>CCOC(=O)c1cnn(C2CCN(C(=O)Cn3nc(C(F)(F)F)cc3C)CC2)n1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US05166347,COC(=NC#N)c1ccccn1.NCc1cccs1>>N#CNC(=NCc1cccs1)c1ccccn1,,CO,,,,test
US20080161352A1,C=O.CO.Cc1cccc2c1C(=O)CCS2>>Cc1cccc2c1C(=O)C(CO)(CO)CS2,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20050171061A1,CC1(C)CNCCN1.O=[N+]([O-])c1ccc(Cl)cc1F>>CC1(C)CN(c2cc(Cl)ccc2N)CCN1,,CN(C)C=O,,CCN(CC)CC,,test
US20110009413A1,COS(C)(=O)=O.Nc1nccnn1>>CN1NC=CN=C1N.CS(=O)(=O)O,,CO,,CN(C)C=O,,test
US20070259854A1,BrCc1ccccc1.O=C(NC1CC1)c1ccc(O)cc1>>O=C(NC1CC1)c1ccc(OCc2ccccc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110117073A1,CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(NCC(=O)OC(C)(C)C)cc3)cc2)ccn1>>CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(NC)cc3)cc2)ccn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020028807A1,CCN1c2ncc(CCOc3ccnc4ccccc34)cc2C(=O)N(C)c2ccc(C(F)(F)F)nc21.O=C(OO)c1cccc(Cl)c1>>CCN1c2ncc(CCOc3cc[n+]([O-])c4ccccc34)cc2C(=O)N(C)c2ccc(C(F)(F)F)nc21,,ClCCl,,,,test
US20110098330A1,Cc1ccccc1C=O.Ic1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.O=Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>Cc1ccccc1C(O)(c1ccccc1)c1cncn1C(c1ccccc1)(c1ccccc1)c1ccccc1,,ClCCl,,CC[Mg]Br,,test
US20130190512A1,CCN(CC)CCN.Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)On1nnc2cccnc21>>CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C,,CN(C)C=O,,,,test
US04337341,COc1cccc(C23CCCC2CN(C)CC3)c1.Cl>>COc1cccc(C23CCCC2C[NH+](C)CC3)c1.[Cl-],,CCOCC,,,,test
US05055458,CCOP(=O)(COCC(CO[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)OCC>>CCOP(=O)(COCC(CO)O[Si](C)(C)C(C)(C)C)OCC,,CC(=O)O,,,,test
US20100184942A1,CC(C)Cn1c2ccccc2c2cc(Br)ccc21.CC(C)OB1OC(C)(C)C(C)(C)O1>>CC(C)Cn1c2ccccc2c2cc(B3OC(C)(C)C(C)(C)O3)ccc21,,C1CCOC1,,[Li]CCCC,,test
US20040116694A1,CCOC(=O)C(=O)CC(C)(C)c1ccc(Br)c2c1OCO2.C[Si](C)(C)C(F)(F)F>>CCOC(=O)C(O)(CC(C)(C)c1ccc(Br)c2c1OCO2)C(F)(F)F,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100184815A1,CC(C)(C)OC(=O)C(C)(C)Oc1ccc(C(=O)O)cc1.OCc1cn(Cc2ccccc2)nn1>>CC(C)(C)OC(=O)C(C)(C)Oc1ccc(C(=O)OCc2cn(Cc3ccccc3)nn2)cc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20090118284A1,COCC1(C(=O)Nc2ccc3[nH]nc(-c4ccnc(C5CC5)c4)c3c2)CCNC1.O=C(CCl)N1CC=C(c2ccc(-c3ncc(F)cn3)c(F)c2)CC1>>COCC1(C(=O)Nc2ccc3[nH]nc(-c4ccnc(C5CC5)c4)c3c2)CCN(CC(=O)N2CC=C(c3ccc(-c4ncc(F)cn4)c(F)c3)CC2)C1,,CN(C)C=O,,CCN(CC)CC,,test
US20030069261A1,C1CCOC1.CCC1=C(C(=O)OCc2ccccc2)C(c2ccc(F)c(F)c2)N(C(=O)Oc2ccc([N+](=O)[O-])cc2)C(OC)=N1>>CCC1=C(C(=O)OCc2ccccc2)C(c2ccc(F)c(F)c2)N(C(=O)N[C@H](C)c2ccccc2)C(OC)=N1,,C1CCOC1,,,,test
US20040142982A1,CNC1CCCCC1.Cn1c(=O)oc(=O)c2ccccc21>>CNc1ccccc1C(=O)N(C)C1CCCCC1,,C1COCCO1,,,,test
US20120184546A1,CC(C)(C)OC(=O)N[C@@H](C(=O)O)c1ccccc1.Nc1ccccc1C(=O)O>>CC(C)(C)OC(=O)N[C@@H](C(=O)Nc1ccccc1C(=O)O)c1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US20150210630A1,C[N+](=O)[O-].Clc1cnc(Cl)c(Cl)c1>>O=[N+]([O-])Cc1ncc(Cl)cc1Cl,,CS(C)=O,,Cl,CC(C)(C)[O-].[K+],test
US20020169200A1,BrC(Br)(Br)Br.O=Cc1ccc2c(c1)OCO2>>BrC(Br)=Cc1ccc2c(c1)OCO2,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20040209894A1,CC(C)[C@@H]1CC[C@@H](N)CC1.Cc1ccc(CCc2cc3ccccc3c(Cl)n2)cn1>>Cc1ccc(CCc2cnc(N[C@@H]3CC[C@@H](C(C)C)CC3)c3ccccc23)cn1,,CCOC(C)=O,,N,O,test
US06630492B1,CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21>>CCC(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC(O)CC(O)CCO)C21,,CCO,,[BH4-].[Li+],,test
US06248740B1,O=C(n1ccnc1)n1ccnc1.OCCOc1ccc2ncnn2n1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>O=C(OCCOc1ccc2ncnn2n1)C1CN(C(c2ccccc2)c2ccccc2)CCN1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20110230457A1,C=O.CCN[C@@H]1CC[C@@H](CN(C)c2ccc(N3C(=O)Cc4cc(OC)c(O[C@H](C)CC)cc4C3c3ccc(Cl)cc3)cc2)CC1>>CC[C@@H](C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N(C)C[C@@H]3CC[C@@H](N(C)CC)CC3)cc1)C2c1ccc(Cl)cc1,,CC#N,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160257651A1,O=Cc1cc(=O)n(C2CC2)c2cc(Br)c(F)cc12>>O=c1cc(CO)c2cc(F)c(Br)cc2n1C1CC1,,CO,,[BH4-].[Na+],[Cl-].[NH4+],test
US04803206,CN=C(NC#N)SC.NCCN>>CNC(=NC#N)NCCN,,CC#N,,,,test
US20090137561A1,COC(=O)c1ccc(-c2cc(C(F)F)ccc2F)c(C2CCCC2(C)C)c1>>CC1(C)CCCC1c1cc(CO)ccc1-c1cc(C(F)F)ccc1F,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20160145276A1,C#Cc1ccccc1.CI.O=Cc1ccccc1C#Cc1ccccc1>>COC(C#Cc1ccccc1)c1ccccc1C#Cc1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US20040072818A1,CC(C)(C)OC(=O)N[C@@H]1CCCCNC1=O.CI>>CN1CCCC[C@@H](NC(=O)OC(C)(C)C)C1=O,,C1CCOC1,,,,test
US05021412,FC(F)(F)C(F)(F)c1ccc(CN=C=S)cc1.NCC(F)(F)F>>FC(F)(F)CNC(=S)NCc1ccc(C(F)(F)C(F)(F)F)cc1,,CCOC(C)=O,,,,test
US06015826,CNN.O=S(=O)(Cl)c1ccc(Cl)cc1>>CN(N)S(=O)(=O)c1ccc(Cl)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20130137865A1,CN(C)CCNS(=O)(=O)c1ccc(C#N)cc1.NO>>CN(C)CCNS(=O)(=O)c1ccc(C(=N)NO)cc1,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US08895313B2,Cc1ccc2nc(-c3ccc(N)cc3)sc2c1.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>Cc1ccc2nc(-c3ccc(NC(=O)c4ccc([N+](=O)[O-])cc4)cc3)sc2c1,,c1ccncc1,,ClCCCl,,test
US20150238558A1,COC[C@H](NCc1ccc(C(=O)OC)cc1)c1ccccc1.O=C(O)[C@@H]1Cc2ccccc2CN1C(=O)OCc1ccccc1>>COC[C@@H](c1ccccc1)N(Cc1ccc(C(=O)OC)cc1)C(=O)[C@@H]1Cc2ccccc2CN1C(=O)OCc1ccccc1,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US03982018,CCCCN.O=C(O)c1cc([N+](=O)[O-])c(Cl)c(S(=O)(=O)Cl)c1>>CCCCNS(=O)(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1Cl,,O,,[Na+].[OH-],,test
US20030153556A1,O=C(O)c1ccc(I)cc1.OB(O)c1ccc(Cl)cc1>>O=C(O)c1ccc(-c2ccc(Cl)cc2)cc1,,CCCCO,O,Cc1ccccc1,O=C([O-])[O-].[Cs+].[Cs+],test
US20110039823A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.COc1ccc2nccc(Br)c2n1>>COc1ccc2nccc(C3(O)CCN(C(=O)OC(C)(C)C)CC3)c2n1,,C1CCOC1,,[Li]CCCC,,test
US20110152318A1,C=Cc1cc(B2OC(C)(C)C(C)(C)O2)cc(C(F)(F)F)c1.CC(NC(=O)c1ccc(Br)o1)c1cc(F)c(NS(C)(=O)=O)c(F)c1>>C=Cc1cc(-c2ccc(C(=O)NC(C)c3cc(F)c(NS(C)(=O)=O)c(F)c3)o2)cc(C(F)(F)F)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030078271A1,Clc1cc(N2CCCCC2)nc(Cl)n1.FC(F)(F)c1cccnc1N1CCNCC1>>FC(F)(F)c1cccnc1N1CCN(c2nc(Cl)cc(N3CCCCC3)n2)CC1,,Clc1ccccc1,,,,test
US20160115126A1,CNC1CCCN(c2ccc(C(N)=O)c3[nH]c(C)c(C)c23)C1.O=S(=O)(Cl)CCCl>>C=CS(=O)(=O)N(C)C1CCCN(c2ccc(C(N)=O)c3[nH]c(C)c(C)c23)C1,,ClCCl,,C1CCOC1,CCN(C(C)C)C(C)C,test
US20150094474A1,CO.Cc1cc(C#N)cc(C(=O)O)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl>>COC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl,,Cc1ccccc1,O,CCN(CC)CC,O=S(Cl)Cl,test
US20120208796A1,CN.O=c1[nH]c2ccc(O)cc2c(=O)o1>>CNC(=O)c1cc(O)ccc1N,,CCO,,,,test
US20040097507A1,COC(=O)c1c(-c2cccnc2Cl)noc1C>>Cc1onc(-c2cccnc2Cl)c1C(=O)O,,C1CCOC1,,CCO,[Na+].[OH-],test
US20140221345A1,CCOC(=O)CBr.COc1ccc2cccc(O)c2n1>>CCOC(=O)COc1cccc2ccc(OC)nc12,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140057895A1,CC(=O)Cl.CC(C)c1nn(-c2noc([C@@H]3C[C@H](N(CCCN)S(=O)(=O)c4ccccc4[N+](=O)[O-])C3)n2)c2c(F)cccc12>>CC(=O)NCCCN([C@H]1C[C@@H](c2nc(-n3nc(C(C)C)c4cccc(F)c43)no2)C1)S(=O)(=O)c1ccccc1[N+](=O)[O-],,ClCCl,,CCN(CC)CC,,test
US20110071197A1,CNc1ccc(O)cc1.COC(=O)c1cc(F)ccc1[N+](=O)[O-]>>CNc1ccc(Oc2ccc([N+](=O)[O-])c(C(=O)OC)c2)cc1,,CN(C)C=O,,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US20090005409A1,Cc1[nH]c2ccnc(N3CCc4ccccc4C3)c2c1C.Cl>>Cc1[nH]c2ccnc(N3CCc4ccccc4C3)c2c1C.Cl,,CCOC(C)=O,,,,test
US20120172351A1,COC(=O)C[C@@H]1COc2cc(N)ccc21.Cc1c(C=O)cccc1-n1c([C@H]2CCCO2)nc2cc(Cl)ccc21>>COC(=O)C[C@@H]1COc2cc(NCc3cccc(-n4c([C@H]5CCCO5)nc5cc(Cl)ccc54)c3C)ccc21,,CC#N,CC(=O)O,[Na+].[OH-],,test
US20140187553A1,COc1ccc(COc2cc(-c3c[nH]c4ccc(-c5nnc(NC(C)C)o5)cc34)nc(NC(C)C)n2)cc1>>CC(C)Nc1nc(-c2c[nH]c3ccc(-c4nnc(NC(C)C)o4)cc23)cc(=O)[nH]1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040053973A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(=O)C1CCNCC1>>CC(C)(C)OC(=O)N1CCC(C(N)=O)CC1,,O,,,,test
US20120046278A1,CCOC(=O)c1nc(N2CCN(C(=O)COc3ccc(Cl)cc3)CC2)c2cc(-c3ccc(F)cc3)sc2n1.COCCN>>COCCNC(=O)c1nc(N2CCN(C(=O)COc3ccc(Cl)cc3)CC2)c2cc(-c3ccc(F)cc3)sc2n1,,CO,,,,test
US20060160877A1,CC(=O)Cl.Nc1cccc(-c2cccc3cc(C(=O)N[C@H]4CN5CCC4CC5)oc23)c1>>CC(=O)Nc1cccc(-c2cccc3cc(C(=O)N[C@H]4CN5CCC4CC5)oc23)c1.Cl,,C1CCOC1,,CCN(CC)CC,,test
US20040082611A1,CCOC(=O)C1CN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CCN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CC1C(=O)O,,C1CCOC1,,CCO,[Na+].[OH-],test
US20070167440A1,N[C@@H]1CCN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1.O=C(Cl)c1ccc(OC(F)(F)F)cc1>>O=C(N[C@@H]1CCN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1)c1ccc(OC(F)(F)F)cc1,,ClCCl,,CCN(CC)CC,O,test
US20150011528A1,CCOC(=O)CBr.Cc1ccc(C(=O)N=c2[nH]c3ccc(F)c(F)c3s2)cc1>>CCOC(=O)Cn1c(=NC(=O)c2ccc(C)cc2)sc2c(F)c(F)ccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040006067A1,CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(c2ccccc2N)CC1.CC(C)(C)OC(=O)NCC=O>>CC(C)(C)OC(=O)NCCNc1ccccc1C1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)OC(C)(C)C)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05268389,CCC1=C(C(=O)O)SCCO1.CCOC(=O)c1cc(N)ccc1Cl>>CCOC(=O)c1cc(NC(=O)C2=C(CC)OCCS2)ccc1Cl,,CCO,ClCCl,CCN(CC)CC,O=S(Cl)Cl,test
US20150158851A1,CCOC(=O)C(c1ccccc1)n1cc(NC(=O)c2nn(COCC[Si](C)(C)C)c3c2CCC(C)(C)C3)cn1>>CC1(C)CCc2c(C(=O)Nc3cnn(C(CO)c4ccccc4)c3)nn(COCC[Si](C)(C)C)c2C1,,C1CCOC1,C1CCOC1,CCOC(C)=O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20020028832A1,CC(C)(C)[Si](Oc1ccc(OCC2CO2)cc1)(c1ccccc1)c1ccccc1.Cc1ccc(CCCNC(=O)N2CCC(Nc3ccc(CCN)cc3)CC2)cc1>>Cc1ccc(CCCNC(=O)N2CCC(Nc3ccc(CCNC[C@H](O)COc4ccc(O)cc4)cc3)CC2)cc1,,CO,ClC(Cl)Cl,,,test
US20080280875A1,CC(C)OC(=O)/N=N/C(=O)OC(C)C.CCOC(=O)c1cc(O)c2sc(C)cc2c1.ClCCl.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CCOC(=O)c1cc(OC(C)Cc2ccccc2)c2sc(C)cc2c1,,ClCCl,,,,test
US20080207654A1,CCCCc1nc(C)n(Cc2cc3cc(C)ccc3s2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nc(C)n(Cc2cc3cc(C)ccc3s2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20070299258A1,CC(C)(C)OC(=O)NC(CC(=O)O)C1CCC1>>CC(C)(C)OC(=O)NC(CCO)C1CCC1,,C1CCOC1,,,,test
US20040077859A1,CC(=O)OC(C)=O.COc1ccc(-c2cnc3c(n2)C(=O)NC(N)(N)N3)cc1OC>>COc1ccc(-c2cnc3c(n2)C(=O)NC(N)(NC(C)=O)N3)cc1OC,,CC(=O)O,,,,test
US05464808,Nc1ccccc1C(=O)C1CC1>>Nc1ccccc1C(O)C1CC1,,C1CCOC1,,CCOC(C)=O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20150133289A1,CCCc1ccc(C(=O)Cl)cc1.CCOC(=O)OC(C)CC(C)O>>CCCc1ccc(C(=O)OC(C)CC(C)OC(=O)OCC)cc1,,ClCCl,,c1ccncc1,,test
US04418065,CNC.ClCC=C(c1ccc(Cl)cc1)c1cccnc1.O=C(O)C(=O)O>>CN(C)C/C=C(/c1ccc(Cl)cc1)c1cccnc1.O=C(O)C(=O)O,,CC(C)=O,ClCCl,O,,test
US20100298290A1,C[Si](C)(C)CCOCCl.Cc1nc2ncc(Br)cc2[nH]1>>Cc1nc2ncc(Br)cc2n1COCC[Si](C)(C)C,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20110212918A1,O=P(Cl)(Cl)Cl.O=[N+]([O-])c1cnc(O)c(C(F)(F)F)c1>>O=[N+]([O-])c1cnc(Cl)c(C(F)(F)F)c1,,O=P(Cl)(Cl)Cl,,ClP(Cl)(Cl)(Cl)Cl,,test
US20050026925A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cc2cc3n(c2nc1Cl)[C@H](C)CNC3>>Cc1cc2cc3n(c2nc1Cl)[C@H](C)CN(C(=O)OC(C)(C)C)C3,CN(C)c1ccncc1,ClCCl,,,,test
US06011039,C=CCOC(=O)Nc1cc(Cl)cc(CN(C(=O)OC(C)(C)C)c2cc(N3CCOCC3)cc(CCc3nc(C)c(CC)s3)n2)c1>>C=CCOC(=O)Nc1cc(Cl)cc(CNc2cc(N3CCOCC3)cc(CCc3nc(C)c(CC)s3)n2)c1,,O=C(O)C(F)(F)F,,,,test
US06211242B1,CCOC(=O)CCCOc1ccccc1N(C)C(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C)cc2)cc1>>Cc1ccc(-c2ccccc2C(=O)Nc2ccc(C(=O)N(C)c3ccccc3OCCCC=O)cc2)cc1,,Cc1ccccc1,ClCCl,CC(C)C[Al+]CC(C)C.[H-],,test
US20050153959A1,COC(=O)C(N)Cc1cc(C)c2[nH]ncc2c1.O=C(c1ncc[nH]1)c1ncc[nH]1.O=C1Nc2c(F)cccc2CN1C1CCNCC1>>COC(=O)C(Cc1cc(C)c2[nH]ncc2c1)NC(=O)N1CCC(N2Cc3cccc(F)c3NC2=O)CC1,,C1CCOC1,,,,test
US20080004300A1,CC(C)Nc1ccc([N+](=O)[O-])cc1C(=O)NN1CCN(C)CC1>>CC(C)Nc1ccc(N)cc1C(=O)NN1CCN(C)CC1,[Zn],CC(=O)O,,O,,test
US20050096380A1,COc1cc2c(cc1Br)C(=O)CC(C)(C)O2.C[Mg]Br>>COc1cc2c(cc1Br)C(C)=CC(C)(C)O2,,C1CCOC1,ClCCl,Cc1ccc(S(=O)(=O)O)cc1,,test
US20030018194A1,CC(=O)/C=C/C1(C2(C)OCCO2)CC1>>CC(=O)CCC1(C2(C)OCCO2)CC1,O=[Pt]=O,C1CCOC1,,[H][H],,test
US20130267510A1,CC(C)(C)OC(=O)NC1(C(=O)O)CCC1.CC1(C)COc2cccc(Oc3ccc(N)cn3)c21>>CC(C)(C)OC(=O)NC1(C(=O)Nc2ccc(Oc3cccc4c3C(C)(C)CO4)nc2)CCC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040209929A1,CCOC(=O)CCBr.Clc1ccnc2[nH]ccc12>>CCOC(=O)CCn1ccc2c(Cl)ccnc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],O=C([O-])O.[Na+],test
US20120094958A1,CCOP(=O)(OCC)c1ccc2cc([N+](=O)[O-])cc(-c3cccc4ccccc34)c2n1>>CCOP(=O)(OCC)c1ccc2cc(N)cc(-c3cccc4ccccc34)c2n1,[Ni],C1CCOC1,,,,test
US20070004736A1,O=C(O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1.O=S(Cl)Cl>>O=C(Cl)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1,CN(C)C=O,Cc1ccccc1,,,,test
US20060235015A1,COc1ccc(NC2=C(c3ccccc3)C(=O)NC2=O)cc1.OCc1ccoc1>>COc1ccc(NC2=C(c3ccccc3)C(=O)N(Cc3ccoc3)C2=O)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020177613A1,COc1ccc(-c2c(OC(C)C)c(=O)c2=O)cc1.NCCc1cccc(C(F)(F)F)c1>>COc1ccc(-c2c(NCCc3cccc(C(F)(F)F)c3)c(=O)c2=O)cc1,,CCO,,,,test
US20140179680A1,O=C(OCc1ccccc1)N1CCO[C@@H]2CCC[C@H]21>>C1C[C@H]2OCCN[C@@H]2C1,[Pd],CCOC(C)=O,,[H][H],,test
US20120283222A1,COC(=O)c1ccc(/C=C(\C)C(=O)OC(C)(C)C)s1>>C/C(=C\c1ccc(C(=O)O)s1)C(=O)OC(C)(C)C,,C1CCOC1,,Cl,[Li+].[OH-],test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2c(OC)cc(OC)cc23)cc1.COc1ccc(N)cc1OC>>COc1cc(OC)c2nc(Nc3ccc(OC)c(OC)c3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US20160060233A1,O=C(NC1CCc2cc(-c3ncn(-c4ccc(OC(F)(F)F)cc4)n3)ccc2C1)OCc1ccccc1>>NC1CCc2cc(-c3ncn(-c4ccc(OC(F)(F)F)cc4)n3)ccc2C1,[Pd],CCOC(C)=O,,,,test
US05552534,CO[C@@H]1O[C@H](CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>CO[C@@H]1O[C@H](CO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040019098A1,Nc1ccc2c(c1)C(=C1C(=O)Nc3ccccc31)OC2.O=C(Cl)CCCCl>>O=C(CCCCl)Nc1ccc2c(c1)C(=C1C(=O)Nc3ccccc31)OC2,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090197883A1,CC1CC(c2ccccc2)(c2cc(OCc3ccc4cc(F)ccc4n3)ccc2C=O)C1.C[Mg]Br>>CC1CC(c2ccccc2)(c2cc(OCc3ccc4cc(F)ccc4n3)ccc2C(C)O)C1,,C1CCOC1,,,,test
US20120083489A1,CC(=O)Cl.NCCNc1ccc(-n2ccc(OCc3ccc(Cl)cn3)cc2=O)cn1>>CC(=O)NCCNc1ccc(-n2ccc(OCc3ccc(Cl)cn3)cc2=O)cn1,,ClCCl,,,,test
US20040097739A1,CCOC(=O)C(C)(C)Oc1ccc(C(O)CCc2nc(-c3ccccc3Cl)oc2C(C)C)cc1>>CC(C)c1oc(-c2ccccc2Cl)nc1CC=Cc1ccc(OC(C)(C)C(=O)O)cc1,,CCO,O,Cl,[Li+].[OH-],test
US20020016460A1,Nc1ccc2c(c1[N+](=O)[O-])c(=O)[nH]c1ccccc12.O=C(O)C(F)(F)F>>Nc1ccc2c(c1N)c(=O)[nH]c1ccccc12.O=C(O)C(F)(F)F,[Pd],,,,,test
US20110098276A1,C=O.NOC1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1>>CNOC1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1,,CCOC(C)=O,ClCCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100173888A1,CC(C)(C)OC(=O)NCC(=O)N[C@@H]1CC[C@@H](NC(=O)c2ccc(-c3cccc(F)c3)nc2)CC1>>NCC(=O)N[C@@H]1CC[C@@H](NC(=O)c2ccc(-c3cccc(F)c3)nc2)CC1,,C1COCCO1,ClCCl,Cl,,test
US20110053905A1,Cc1ccc(F)c(N=C=O)c1.Nc1ccc(-c2ccnc(-c3ccc[nH]3)c2)cc1>>Cc1ccc(F)c(NC(=O)Nc2ccc(-c3ccnc(-c4ccc[nH]4)c3)cc2)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20120289474A1,COCn1nnc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(-c4ccccc4)cc32)n1.O=C(O)C(F)(F)F>>COCn1nnc(Cn2c(=O)n(C3CCNCC3)c(=O)c3sc(-c4ccccc4)cc32)n1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20080102391A1,C=CC(=O)Cl.Cc1ccc(N(c2ccc(C)cc2)c2ccc(C=Cc3ccccc3O)cc2)cc1>>C=CC(=O)Oc1ccccc1C=Cc1ccc(N(c2ccc(C)cc2)c2ccc(C)cc2)cc1,,O,,C1CCOC1,O=C([O-])O.[Na+],test
US20050107419A1,C1CCNCC1.CC(C)(C)OC(=O)N1CCCC1C(=O)CC=O.CCOC(=O)/C=C(\N)CCc1ccc(C(F)(F)F)cc1.COC(OC)OC.O=C(O)c1ccc([N+](=O)[O-])cc1>>CCOC(=O)c1c(CCc2ccc(C(F)(F)F)cc2)nc2c(c1-c1ccc(NC(=O)Nc3ccccc3)cc1)C(=O)N1CCC[C@@H]21,,CN(C)C=O,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US05439925,CC1(C)CCC(C)(C)c2cc(CC(=O)Oc3ccc(C(=O)OCc4ccccc4)cc3)ccc21>>CC1(C)CCC(C)(C)c2cc(CC(=O)Oc3ccc(C(=O)O)cc3)ccc21,[Pd],CCOCC,,C1COCCO1,,test
US20150291562A1,CC(C)(C)OC(=O)NCCOCCOCCOCCCOc1ccc(N2C(=S)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C2(C)C)cc1>>CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=S)N1c1ccc(OCCCOCCOCCOCCN)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20130210818A1,NC(=S)c1ccccc1.O=C(CBr)c1ccncc1>>c1ccc(-c2nc(-c3ccncc3)cs2)cc1,,CN(C)C=O,,Br,,test
US20110053893A1,COc1ccc(CCc2cnc3c(N)nc4cc(CO)ccc4c3c2)c(C)c1>>COc1ccc(CCc2cnc3c(N)nc4cc(C=O)ccc4c3c2)c(C)c1,,CS(C)=O,O,,,test
US20040072818A1,Fc1ccccn1.O=C(NC1CCCCC(O)C1)N1CCN(c2ccnc3cc(Cl)ccc23)CC1>>O=C(NC1CCCCC(Oc2ccccn2)C1)N1CCN(c2ccnc3cc(Cl)ccc23)CC1,,CO,ClCCl,[H-].[Na+],,test
US20110207728A1,CCOC(=O)C=C(C(=O)OCC)N(CC(=O)c1ccc(OC)cc1)NC(=O)OC(C)(C)C>>CCOC(=O)c1cc(=O)[nH]n1CC(=O)c1ccc(OC)cc1,,Cc1ccccc1,,,,test
US06300352B1,C[C@H](Oc1ccc(B(O)O)cc1)[C@H](O)CCc1cccnc1.O=S(=O)(NN1CCCC1)c1cccc(Br)c1>>C[C@H](Oc1ccc(-c2cccc(S(=O)(=O)N3CCCC3)c2)cc1)[C@H](O)CCc1cccnc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US04820703,CC(C)Cc1ccc(CCc2cc3c(s2)NC(=O)C(C)N=C3c2ccccc2Cl)cc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)Cc1ccc(CCc2cc3c(s2)NC(=S)C(C)N=C3c2ccccc2Cl)cc1,,Cc1ccccc1,,,,test
US20100324041A1,O=S(=O)(c1ccccc1)n1ccc2c(Cl)c(Br)cnc21.OB(O)c1ccccc1>>O=S(=O)(c1ccccc1)n1ccc2c(Cl)c(-c3ccccc3)cnc21,,CCO,,Cc1ccccc1,,test
US06166219,CCOC(=O)c1ccc([N+](=O)[O-])c(N)c1>>CCOC(=O)c1ccc(N)c(N)c1,[Pd],CO,,[H][H],,test
US05972888,CCCCCS(=O)(=O)c1ccc(-c2sc3cc(S(=O)(=O)CCCCC)ccc3c2C(=O)c2ccc(OCCN3CCCCC3)cc2)cc1.Cl>>CCCCCS(=O)(=O)c1ccc(-c2sc3cc(S(=O)(=O)CCCCC)ccc3c2C(=O)c2ccc(OCCN3CCCCC3)cc2)cc1.Cl,,CCOC(C)=O,,,,test
US20100144760A1,CC(C)(C)OC(=O)N1CC=CC[C@H]1C(=O)O.CO>>COC(=O)[C@@H]1CC=CCN1C(=O)OC(C)(C)C,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20080221197A1,COC(=O)c1cn(-c2ccccc2C(C)C)c2ccccc12>>CC(C)c1ccccc1-n1cc(C(=O)O)c2ccccc21,,CC(C)O,,[Na+].[OH-],,test
US20160194315A1,CCC(O)c1cc2nccc(C(=O)OC)c2[nH]1>>CCC(O)c1cc2nccc(C(=O)O)c2[nH]1,,CC#N,O,,,test
US20150322020A1,CCOc1c(NC[C@H](NC(=O)c2ccc(Nc3nc(NC4(c5ccc(Cl)cc5)CC4)nc(OCC(F)(F)F)n3)cc2)C(=O)OC)c(=O)c1=O>>CCOc1c(NC[C@H](NC(=O)c2ccc(Nc3nc(NC4(c5ccc(Cl)cc5)CC4)nc(OCC(F)(F)F)n3)cc2)C(=O)O)c(=O)c1=O,,CC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US06172061B2,CI.Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CN4CCC(O)CC4)cc2)CC3)cc1>>Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(C[N+]4(C)CCC(O)CC4)cc2)CC3)cc1.[I-],,CN(C)C=O,,CCOC(C)=O,,test
US20130116234A1,C1CCNCC1.FC(F)(F)c1ccc2nc(Cl)c(-c3nnn[nH]3)c(-c3ccccc3)c2c1>>FC(F)(F)c1ccc2nc(N3CCCCC3)c(-c3nnn[nH]3)c(-c3ccccc3)c2c1,,CC(=O)N(C)C,,CCN(CC)CC,Cl,test
US20070049618A1,CCCC(=O)Cl.NCc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O>>CCCC(=O)NCc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O,,CC#N,,C1CCC2=NCCCN2CC1,Cl,test
US20150309042A1,Clc1nc(Cl)nc(Cl)n1.[N-]=[N+]=Nc1cc2ccc(O)cc2oc1=O>>[N-]=[N+]=Nc1cc2ccc(Oc3nc(Cl)nc(Cl)n3)cc2oc1=O,,CC(C)=O,,CCN(C(C)C)C(C)C,,test
US04166817,CCOC(=O)c1cnc2nc(C)ccc2c1O.O=P(Cl)(Cl)Cl>>CCOC(=O)c1cnc2nc(C)ccc2c1Cl,,CO,ClC(Cl)Cl,[Br-].[K+],,test
US04689345,CCC(CCCCC1CCC2CC(O)CC12)OC.CI>>CCC(CCCCC1CCC2CC(OC)CC12)OC,,C1CCOC1,,[I-].[Na+],,test
US08524691B2,O=C(O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21>>NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O,,CN(C)C=O,,C1CCNCC1,,test
US20060167255A1,CS(=O)(=O)OCCC1CCCc2cc(S(=O)(=O)c3ccccc3)ccc21.c1c[nH]cn1>>O=S(=O)(c1ccccc1)c1ccc2c(c1)CCCC2CCn1ccnc1,,CC#N,O,[I-].[K+],,test
US20140121200A1,CC(C)(C)OC(=O)N1CCC(F)(F)C(CNc2nc(Cl)cc3nccnc23)C1.CCOC(=O)CN(C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>CCOC(=O)CN(C)c1ccc(-c2cc3nccnc3c(NCC3CN(C(=O)OC(C)(C)C)CCC3(F)F)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110183985A1,COC(=O)c1cc(Cl)c(I)c([N+](=O)[O-])c1O.N#C[Cu]C#N>>COC(=O)c1cc(Cl)c(C#N)c([N+](=O)[O-])c1O,,CN(C)C=O,,,,test
US05041448,NCc1ccccn1.Nc1c(Cl)ncnc1Cl>>Nc1c(Cl)ncnc1NCc1ccccn1,,O,,CCN(CC)CC,,test
US20160068531A1,CS(=O)(=O)CCCc1c(COS(C)(=O)=O)n(S(=O)(=O)c2ccccc2)c2cc(Cl)ccc12.O=C1Nc2cnccc2C12CC2>>CS(=O)(=O)CCCc1c(CN2C(=O)C3(CC3)c3ccncc32)n(S(=O)(=O)c2ccccc2)c2cc(Cl)ccc12,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05998433,CN(C)Cc1cc2c(o1)CN(S(=O)(=O)c1ccc(/C=C\c3ccccc3)cc1)CC2.Cl>>CN(C)Cc1cc2c(o1)CN(S(=O)(=O)c1ccc(/C=C\c3ccccc3)cc1)CC2.Cl,,CO,,,,test
US20110257402A1,CI.Cc1cc(F)ccc1-c1c(NC(=O)OC(C)(C)C)cnc2c1cnn2Cc1ccccc1>>CNc1cnc2c(cnn2Cc2ccccc2)c1-c1ccc(F)cc1C,,CN(C)C=O,,[H-].[Na+],,test
US06011029,CC(=O)N1Cc2cc(-c3ccccc3)ccc2N(Cc2c[nH]cn2)C[C@H]1Cc1ccccc1.Cl.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>Cl.O=C(N1Cc2cc(-c3ccccc3)ccc2N(Cc2c[nH]cn2)C[C@H]1Cc1ccccc1)C(F)(F)F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120172599A1,CC1=C(C#N)C(=C(C#N)C#N)OC1(C)C(F)(F)F.CCCCN(CCCC)c1ccc(C=Cc2ccc(C=O)cc2)c(OC)c1>>CCCCN(CCCC)c1ccc(C=Cc2ccc(C=CC3=C(C#N)C(=C(C#N)C#N)OC3(C)C(F)(F)F)cc2)c(OC)c1,,C1CCOC1,CCO,,,test
US20140135332A1,NC(=O)c1c(F)ccc(OC(CO)c2nc(-c3ccc(C(F)(F)F)cc3)c(Br)o2)c1F.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>NC(=O)c1c(F)ccc(OC(COC(=O)Oc2ccc([N+](=O)[O-])cc2)c2nc(-c3ccc(C(F)(F)F)cc3)c(Br)o2)c1F,,ClCCl,,O,c1ccncc1,test
US20060160830A1,C[C@@]1(OC(=O)c2ccccc2)[C@H](OC(=O)c2ccccc2)[C@@H](COC(=O)c2ccccc2)O[C@H]1n1c(=O)sc2c(=O)[nH]c(N)nc21>>C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1c(=O)sc2c(=O)[nH]c(N)nc21,,CO,,N,,test
US20050026989A1,COC(=O)c1cn(-c2nccc3ccccc23)c2ccc(C)cc12>>Cc1ccc2c(c1)c(C(=O)O)cn2-c1nccc2ccccc12,,C1CCOC1,O,[Li+].[OH-],,test
US05637593,CN1CCC(=O)CC1.c1ccc(Sc2ccc3[nH]ccc3c2)cc1>>CN1CC=C(c2c[nH]c3ccc(Sc4ccccc4)cc23)CC1,,CO,,C[O-].[Na+],,test
US20030003245A1,C[Si](C)(CCCCOc1cnc(-c2ccc(OCc3ccccc3)cc2)nc1)CCC(F)(F)F>>C[Si](C)(CCCCOc1cnc(-c2ccc(O)cc2)nc1)CCC(F)(F)F,[Pd],CCO,CCOC(C)=O,,,test
US20150246912A1,CCOC(=O)CC(=O)C(F)(F)F.CCOC(OCC)OCC>>CCO/C=C(\C(=O)OCC)C(=O)C(F)(F)F,,CC(=O)OC(C)=O,,,,test
US20120207703A1,COc1ccc(COc2cc(Cl)nc(-c3nc(C(F)(F)F)cs3)n2)cc1.Oc1ccccc1>>COc1ccc(COc2cc(Oc3ccccc3)nc(-c3nc(C(F)(F)F)cs3)n2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20150274777A1,CCCCC(NC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](C)NC(=O)CN1CCOCC1)[C@H](O)C(=O)NC>>CCCC[C@H](NC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](C)NC(=O)CN1CCOCC1)C(=O)C(=O)NC,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20120059030A1,CCI.COc1cc(-c2nnc3n2CCCC3c2ccc(F)c(F)c2)ccc1-c1cnc(C)o1.O>>CCOC1(c2ccc(F)c(F)c2)CCCn2c(-c3ccc(-c4cnc(C)o4)c(OC)c3)nnc21,,O,,CN(C)C=O,[H-].[Na+],test
US20120122811A1,C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1c1ccc2c(N)ncnn12.O=C1CCC(=O)N1Cl>>C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1c1cc(Cl)c2c(N)ncnn12,,CN(C)C=O,,,,test
US20100286211A1,N#Cc1ccc(Br)cc1F.[N-]=[N+]=[N-]>>Fc1cc(Br)ccc1-c1nnn[nH]1,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US20110275797A1,CC(C)(C)OC(=O)N1CCC(O)CC1.COC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1ccc(O)cc1O>>COC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1O,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030149001A1,Cc1cc(=O)n(C2CCCC2)c2nc(Nc3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)cn3)ncc12.Cl>>Cc1cc(=O)n(C2CCCC2)c2nc(Nc3ccc(N4CCNCC4)cn3)ncc12.Cl,,CCOCC,Cl,ClCCl,,test
US20070123522A1,CC(C)(C)CC(=O)Cl.CCOC(=O)C(C)(C)Cc1cc2nc(OC)ccc2n1Cc1ccc(Cl)cc1>>CCOC(=O)C(C)(C)Cc1c(C(=O)CC(C)(C)C)c2nc(OC)ccc2n1Cc1ccc(Cl)cc1,,CC(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120264734A1,CCN(c1cc(Br)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCCC1.OB(O)c1ccc(CN2CCOCC2)cc1>>CCN(c1cc(-c2ccc(CN3CCOCC3)cc2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20020193599A1,CC(=O)C=C(C)N.N#CCCOC(=O)C(=Cc1ccc([N+](=O)[O-])cc1)C(=O)CCCCN=[N+]=[N-]>>CC(=O)C1=C(C)NC(CCCCN=[N+]=[N-])=C(C(=O)OCCC#N)C1c1ccc([N+](=O)[O-])cc1,,CCO,,,,test
US05705499,CC(C)(C)OC(=O)n1cccc1.CCN1c2ncc(CCc3ccccc3)cc2C(=O)N(C)c2ccc(Cl)nc21>>CCN1c2ncc(CCc3ccccc3)cc2C(=O)N(C)c2ccc(-c3ccc[nH]3)nc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,CC(=O)[O-].[K+],,test
US06028109,CCCCCCCN(CCc1ccc(OC(C)(C)C(=O)OCC)cc1)C(=O)Nc1ccc(F)cc1>>CCCCCCCN(CCc1ccc(OC(C)(C)C(=O)O)cc1)C(=O)Nc1ccc(F)cc1,,CCO,,Cl,[Na+].[OH-],test
US20100204196A1,COc1cc2c(cc1Nc1nc3c(ccn3S(=O)(=O)c3ccc(C)cc3)c3nc4cc(F)cc(F)c4c(=O)n13)N(C(=O)CN(C)C)CC2.NCc1ccc(F)cc1>>COc1cc2c(cc1Nc1nc(Nc3cc(F)cc(F)c3C(=O)NCc3ccc(F)cc3)c3ccnc-3[nH]1)N(C(=O)CN(C)C)CC2,,C1CCOC1,CCOC(C)=O,,,test
US20040180939A1,CC(=O)c1ncc[nH]1.CC(C)(C)OC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNC(C)(C)c1cccc(Br)c1.Cl>>CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@@H](CNC(C)(C)c1cccc(Br)c1)OC(C)=O.Cl,,CCOCC,ClCCl,O=C(O)C(F)(F)F,,test
US20100280028A1,CC(C)(C)OC(=O)N1CCN(c2ccccc2C=O)CC1.NS(=O)(=O)O>>CC(C)(C)OC(=O)N1CCN(c2ccccc2C(=O)O)CC1,,C1COCCO1,O,[Na+].[O-]Cl,,test
US20090029968A1,C1CCCNCC1.Nc1ccc(C(=O)O)c(Cl)c1>>Nc1ccc(C(=O)N2CCCCCC2)c(Cl)c1,,ClCCl,,CCN=C=NCCCN(C)C,,test
US20080064715A1,OC(c1ccccc1)c1cc2ccnc(N(Cc3ccccc3)Cc3ccccc3)c2[nH]1>>O=C(c1ccccc1)c1cc2ccnc(N(Cc3ccccc3)Cc3ccccc3)c2[nH]1,O=[Mn]=O,ClCCl,,,,test
US20090131458A1,CCC[C@@H](C)Oc1nc(N)c2nc(OC)n(C3CCCCO3)c2n1.O=C(O)C(F)(F)F>>CCC[C@@H](C)Oc1nc2nc(OC)nc-2c(N)[nH]1.O=C(O)C(F)(F)F,,CCOC(C)=O,CO,,,test
US20150175628A1,CC(C)(C)OC(=O)NCC(=O)NN.COc1cc([N+](=O)[O-])ccc1C(=O)Cl>>COc1cc([N+](=O)[O-])ccc1C(=O)NNC(=O)CNC(=O)OC(C)(C)C,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US05382672,Brc1cccc2ccccc12.CC(C)(C)n1nnc(-c2ccccc2B(O)c2ccccc2-c2nnn(C(C)(C)C)n2)n1>>CC(C)(C)n1nnc(-c2ccccc2-c2cccc3ccccc23)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,[Cl-].[Na+],,test
US06329405B1,COc1c(OC)c(=O)c1=O.COc1ccc(C(NCC(O)c2ccccc2)c2cccc(N)c2)cc1>>COc1ccc(C(NCC(O)c2ccccc2)c2cccc(Nc3c(OC)c(=O)c3=O)c2)cc1,,CO,,,,test
US20080153837A1,NO.O=C1c2ccccc2-c2c1cccc2-c1nc2ccc(Cl)cc2[nH]1>>ON=C1c2ccccc2-c2c1cccc2-c1nc2ccc(Cl)cc2[nH]1,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20100080771A1,C=CCCCCOC(=O)N[C@H](C(=O)O)C(C)(C)C.C=Cc1ccc(Cl)cc1-c1ccc([C@@]2(OC)CN[C@H](C(=O)OC)C2)cc1>>C=CCCCCOC(=O)N[C@H](C(=O)N1C[C@](OC)(c2ccc(-c3cc(Cl)ccc3C=C)cc2)C[C@H]1C(=O)OC)C(C)(C)C,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090042877A1,CC#N.CCO.C[Si](C)(C)[N-][Si](C)(C)C.Cc1ccc(N=C=S)cc1.[Na+]>>Cc1ccc(-n2c([S-])c(C#N)ccc2=O)cc1.[Na+],,C1CCOC1,CC#N,,,test
US05556977,C=CCOc1ccc(N2CCN(c3ccncc3)CC2)cc1>>C=CCc1cc(N2CCN(c3ccncc3)CC2)ccc1O,,CCOCC,,c1ccc(Oc2ccccc2)cc1,,test
US06143764,COCCCN.COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COCCCNC(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1,,CCN(CC)CC,Cc1ccccc1,O=C([O-])O.[Na+],,test
US20100331293A1,CI.Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(Br)cnc1N1CCOCC1>>Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1N(C)c1cc(Br)cnc1N1CCOCC1,,CN(C)C=O,,O,[H-].[Na+],test
US05183820,Cc1[nH]cnc1CN1CCc2c(c3cccc(F)c3n2C)C1=O.Cl>>Cc1[nH]cnc1CN1CCc2c(c3cccc(F)c3n2C)C1=O.Cl,,CO,,,,test
US20100166699A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.Clc1ccc(C2(c3ccc(I)cc3)CNCCO2)cc1>>Clc1ccc(C2(c3ccc(-c4cn[nH]c4)cc3)CNCCO2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US04206089,CCCCCC=C1CCCC1=O.COC(=O)CC(C)=O>>CCCCCC1CC(=O)C=C2CCCC21,,CO,,[Na],,test
US20140336388A1,CN(C)C(=O)Cl.NNC(=O)C1CCN(c2ccc([N+](=O)[O-])cc2)CC1>>O=c1[nH]nc(C2CCN(c3ccc([N+](=O)[O-])cc3)CC2)o1,,c1ccncc1,,,,test
US04548932,CCOC(=O)C(=O)OCC.CCOC(=O)CCCC1CCN(C(=O)OCc2ccccc2)CC1>>CCOC(=O)C(=O)CCCC1CCN(C(=O)OCc2ccccc2)CC1,,CCO,,[Na],,test
US20080269200A1,CC(=O)Cl.NC(=O)c1cc(-c2ccccc2)cc2c(C3CCNCC3)c[nH]c12>>CC(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4ccccc4)cc23)CC1,,c1ccncc1,,,,test
US20140349972A1,CCOP(=O)(OCC)c1ccc(-c2ccc(C(C)(C)NC(=O)c3cnc(-c4cccnn4)nc3O)cn2)cc1>>CC(C)(NC(=O)c1cnc(-c2cccnn2)nc1O)c1ccc(-c2ccc(P(=O)(O)O)cc2)nc1,,ClCCl,,C[Si](C)(C)Br,,test
US04888041,CC(=NO)c1cc(Oc2ccc(Br)cc2F)ccc1[N+](=O)[O-]>>Cc1noc2ccc(Oc3ccc(Br)cc3F)cc12,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20140194431A1,O=C1c2c(OCc3ccccc3)c(=O)nc(CC3(c4ccc(Cl)cc4)CCCC3)n2CCN1C1CCOCC1>>O=C1c2c(O)c(=O)nc(CC3(c4ccc(Cl)cc4)CCCC3)n2CCN1C1CCOCC1,,CC(=O)O,,O=S(=O)(O)O,,test
US20060100229A1,COCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)C#N.OO>>COCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)C(N)=O,,O,,CCO,[Na+].[OH-],test
US20120202856A1,Cn1nc(C(C)(C)C)c(Cl)c1C(=O)Nc1ccc(-c2ccccc2F)cc1[N+](=O)[O-]>>Cn1nc(C(C)(C)C)c(Cl)c1-c1nc2cc(-c3ccccc3F)ccc2[nH]1,[Fe],CC(=O)O,CCO,,,test
US20130336920A1,COC(=O)c1ccnc(-c2cc(N3CCCCC3)ccc2NC(=O)c2cccc(C(=O)N(C)CCN3CCOCC3)c2)c1>>CN(CCN1CCOCC1)C(=O)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)O)ccn2)c1,,C1COCCO1,O,[Li+].[OH-],,test
US20100210656A1,N.N#Cc1ccc(CBr)c(Cl)c1>>N#Cc1ccc(CN)c(Cl)c1,,CO,,Cl,,test
US20130184273A1,CC(C)N.Cc1nc2nc(Cl)c(-c3ccccc3)c(Cl)n2n1>>Cc1nc2nc(Cl)c(-c3ccccc3)c(NC(C)C)n2n1,,CN(C)C=O,O,,,test
US05935973,CC(C)(C)OC(=O)N1CCC(CN)CC1.O=c1[nH]c2ccsc2c(=O)o1>>CC(C)(C)OC(=O)N1CCC(CNC(=O)c2sccc2N)CC1,,COCCOC,,,,test
US04914112,CC(C(=O)CC#N)c1ccc(-c2ccccc2)c(F)c1.NO>>CC(c1ccc(-c2ccccc2)c(F)c1)c1cc(N)on1,,CCO,c1ccncc1,Cl,,test
US04416817,COC1(NC(=O)[C@@H](C)N)CNC1=O.O=C(Cl)Cc1ccccc1>>COC1(N(C(=O)Cc2ccccc2)C(=O)[C@@H](C)N)CNC1=O,,C1CCOC1,CC(=O)N(C)C,CCN(CC)CC,,test
US20080311179A1,BrCCCCCBr.N#CCC#N>>N#CC1(C#N)CCCCC1,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US04027023,CCc1ccc2nnc(C(=O)Cl)cc2c1.COC(=O)CN>>CCc1ccc2nnc(C(=O)NCC(=O)OC)cc2c1,,ClCCl,,CCN(CC)CC,Cl,test
US20100068178A1,COC(=O)c1sccc1N=NN(C)C.NCCO>>CN(C)N=Nc1ccsc1C(=O)NCCO,,C1CCOC1,,O,,test
US20110294807A1,COc1ccc2[nH]c(=O)oc(=O)c2c1.Nc1ccc(Br)cc1>>COc1ccc(N)c(C(=O)Nc2ccc(Br)cc2)c1,,CN(C)C=O,,,,test
US20030125370A1,Cc1[nH]c(C=O)c(C)c1CC(=O)N1CCC[C@H]1CN1CCCC1.O=C1Cc2cc(S(=O)(=O)Cc3ccccc3)ccc2N1>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4ccccc4)cc32)c(C)c1CC(=O)N1CCC[C@H]1CN1CCCC1,,CCO,,C1CCNCC1,,test
US20110118246A1,Nc1cc(-c2cccc3[nH]ccc23)cc2[nH]ncc12.O=C(O)c1cccc(F)n1>>O=C(Nc1cc(-c2cccc3[nH]ccc23)cc2[nH]ncc12)c1cccc(F)n1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090143371A1,COC(=O)/C=C/OC(=O)c1ccc([N+](=O)[O-])cc1.O/N=C(\Cl)c1ccccc1>>COC(=O)c1conc1-c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20060094767A1,Cc1ccc(S(=O)(=O)OCC2(C)CO2)cc1.O=C1NCCN1Cc1ccc(Cl)cc1>>CC1(CN2CCN(Cc3ccc(Cl)cc3)C2=O)CO1,,CN(C)C=O,,O,[H-].[Na+],test
US20040259957A1,CCCCOc1ccc(C=O)cc1O.COc1cc(OC)cc(C(C)=O)c1>>CCCCOc1ccc(/C=C/C(=O)c2cc(OC)cc(OC)c2)cc1O,,CO,,[Na+].[OH-],,test
US20070146835A1,COc1ccc(C=O)cc1.Cc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]>>COc1ccc(C=Cc2ccc([N+](=O)[O-])cc2[N+](=O)[O-])cc1,,Cc1ccccc1C,,C1CCNCC1,,test
US20030195239A1,C#CCCC1(C2CCCC2)CC(=O)C(Sc2ccccc2)C(=O)O1.Oc1cccc(Br)c1>>O=C1CC(CCC#Cc2cccc(O)c2)(C2CCCC2)OC(=O)C1Sc1ccccc1,,CC#N,,CC(=O)O,,test
US04873332,CCN(CC)c1ccc(N=C2C=CC(=O)c3ncccc32)c(C)c1>>Nc1ccc(N=C2C=CC(=O)C=C2)cc1,,CCO,O,,,test
US03952104,CC(=O)O.CCCc1cc(CCC)c2oc(C(N)=O)cc(=O)c2c1>>CCCc1cc(CCC)c2oc(C(=O)O)cc(=O)c2c1,,CC(=O)O,,Br,O,test
US20030176460A1,N#Cc1ccc(/C=C/C(=O)O)cc1.N[C@H](Cc1ccccc1)CN1CCC(C(=O)c2ccc(F)cc2)CC1>>N#Cc1cccc(/C=C/C(=O)N[C@H](Cc2ccccc2)CN2CCC(C(=O)c3ccc(F)cc3)CC2)c1,,ClCCl,,CCN(CC)CC,,test
US20080009491A1,O=C(OC(=O)C(F)(F)F)C(F)(F)F.c1ccc2c(-c3ncc4ccccn34)cccc2c1>>O=C(c1nc(-c2cccc3ccccc23)n2ccccc12)C(F)(F)F,,CN(C)C=O,,O,,test
US20100216788A1,ClCc1cscn1.O=[N+]([O-])c1ccc2[nH]ccc2c1>>O=[N+]([O-])c1ccc2c(ccn2Cc2cscn2)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20150133432A1,CCN=C=O.Cc1n[nH]c2nc(-c3ccc(O)cc3F)cc(CN3CCCNC(C)C3)c12>>CCNC(=O)N1CCCN(Cc2cc(-c3ccc(O)cc3F)nc3[nH]nc(C)c23)CC1C,,O,,C1CCOC1,CCN(C(C)C)C(C)C,test
US04277471,CN(C)CCC=Cc1ccccc1-c1ccccc1>>CN(C)CCCCc1ccccc1-c1ccccc1,[Pd],CCOCC,,CCOC(C)=O,Cl,test
US20120071461A1,CC1(C)CC2(CCC1N)OCCO2.O=C(Cl)OCc1ccccc1>>CC1(C)CC2(CCC1NC(=O)OCc1ccccc1)OCCO2,,Cc1ccccc1,ClCCl,CCN(CC)CC,,test
US20150105373A1,Cc1cnc2c(c1)NC(=O)CN2C(=O)NC(c1ccc(OC(F)(F)F)cc1)C(C)(C)O>>Cc1cnc2c(c1)NC(=O)CN2C(=O)N[C@@H](c1ccc(OC(F)(F)F)cc1)C(C)(C)O,,CCCCCC,CCO,,,test
US20120010183A1,CS(N)(=O)=O.Cc1ccc(OC(=O)c2cc(F)c(Oc3cnc(F)c(Cl)c3)cc2F)cc1>>CS(=O)(=O)NC(=O)c1cc(F)c(Oc2cnc(F)c(Cl)c2)cc1F,,CC#N,CCOC(C)=O,C1CCC2=NCCCN2CC1,,test
US04853410,CC1CC(=O)O1.Oc1cccc(F)c1>>CC(CC(=O)O)Oc1cccc(F)c1,,O,,Cl,[Na+].[OH-],test
US20050137168A1,CC(=O)Cl.CCOC(C(=O)NCc1ccc(C#N)cc1)n1ccc(-c2cccc(N)c2)n1>>CCOC(C(=O)NCc1ccc(C#N)cc1)n1ccc(-c2cccc(NC(C)=O)c2)n1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20080167378A1,COC(=O)CCc1ccc(O)cc1.OCc1ccccc1>>COC(=O)CCc1ccc(OCc2ccccc2)cc1,,C1CCOC1,O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160221998A1,CC(=O)OCC(F)(F)Br.Oc1cc(Cl)nc(Cl)c1>>FC(F)Oc1cc(Cl)nc(Cl)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20160175289A1,C[C@H](Cc1c[nH]c2ccccc12)NCC(F)(F)F.O=Cc1c(F)cc(Br)cc1F>>C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(Br)cc2F)N1CC(F)(F)F,,Cc1ccccc1,,CC(=O)O,,test
US20090099207A1,CC(C)(C)OC(=O)N(Cc1cccc(C(C)(C)C)c1)[C@H]1CS(=O)(=O)C[C@@H](Cc2ccc(Br)cc2)C1=O>>CC(C)(C)OC(=O)N(Cc1cccc(C(C)(C)C)c1)[C@H]1CS(=O)(=O)C[C@@H](Cc2ccc(Br)cc2)[C@@H]1O,,C1CCOC1,,,,test
US20090186879A1,CI.OC(c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1C(F)(F)F)C1CC1>>COC(c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1C(F)(F)F)C1CC1,,CN(C)C=O,O,[H-].[Na+],,test
US20050256201A1,CC1(C)OCc2cc([C@@H]3CN(CCc4ccc(OCCO)cc4)C(=O)O3)ccc2O1.O=[N+]([O-])c1cccc(CBr)c1>>CC1(C)OCc2cc([C@@H]3CN(CCc4ccc(OCCOCc5cccc([N+](=O)[O-])c5)cc4)C(=O)O3)ccc2O1,,CN(C)C=O,,[H-].[Na+],,test
US20090298823A1,Cc1ccc(S(=O)(=O)n2cc(C#N)c3c(NC4CC4)nc(Cl)nc32)cc1.Nc1ccc2cn[nH]c2c1>>N#Cc1c[nH]c2nc(Nc3ccc4cn[nH]c4c3)nc(NC3CC3)c12,,CCCCO,,C[Si](C)(C)Cl,,test
US20130096135A1,COCC(=O)Cl.O=C(Nc1ccc(Oc2ccnc3cc(-c4ccc(CN5CCNCC5)cn4)sc23)c(F)c1)NC1CC1>>COCC(=O)N1CCN(Cc2ccc(-c3cc4nccc(Oc5ccc(NC(=O)NC6CC6)cc5F)c4s3)nc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20070203201A1,Cc1cc([N+](=O)[O-])cc2c(=O)oc(=O)[nH]c12.O=C(Cl)c1cc(C(F)(F)F)nn1-c1ncccc1Cl>>Cc1cc([N+](=O)[O-])cc2c(=O)oc(-c3cc(C(F)(F)F)nn3-c3ncccc3Cl)nc12,,c1ccncc1,,,,test
US04457859,BrBr.CCCCCCCCc1ccc(-c2ccc(C(C)=O)cc2)cc1>>CCCCCCCCc1ccc(-c2ccc(C(=O)CBr)cc2)cc1,,CC(=O)O,,O,,test
US04621082,CCOC(=O)C(=Cc1ccccc1)C(C)=O.Nc1cc(N)nc(N)n1>>CCOC(=O)C1=C(C)Nc2nc(N)nc(N)c2C1c1ccccc1,,CC(=O)O,,,,test
US20130203755A1,Cc1ccc(S(=O)(=O)n2cc(I)c3cc(Br)cnc32)cc1.OB(O)c1ccc(O)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3ccc(O)cc3)c3cc(Br)cnc32)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20090170913A1,CN(C)C1CCN(c2nc3ccc(N)cc3s2)C1.O=C(O)C=Cc1ccc(Cl)c(Cl)c1>>CN(C)C1CCN(c2nc3ccc(NC(=O)C=Cc4ccc(Cl)c(Cl)c4)cc3s2)C1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US07019147B1,COc1cc([N+](=O)[O-])c([N+](=O)[O-])cc1OC>>COc1cc(N)c([N+](=O)[O-])cc1OC,[Fe],O,,CCO,,test
US20050203113A1,CN(C[C@@H](CCO)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1>>CN(C[C@@H](CC=O)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1,,CS(C)=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US04503073,CCCSC(C(N)=O)c1cc(C)cc(C(=O)c2ccc(F)cc2)c1N>>Cc1cc(CC(N)=O)c(N)c(C(=O)c2ccc(F)cc2)c1,[Ni],C1CCOC1,,,,test
US20040053952A1,Cc1c(Cl)[nH]c(=O)n(Cc2ccc(C(=O)OC(C)(C)C)cc2)c1=O.S>>Cc1c(S)[nH]c(=O)n(Cc2ccc(C(=O)OC(C)(C)C)cc2)c1=O,,CN(C)C=O,,[Na],,test
US05428065,Cc1cc(C=O)c(OCCCCCCBr)c(C=O)c1.SCc1ccccc1>>Cc1cc(C=O)c(OCCCCCCSCc2ccccc2)c(C=O)c1,,CCO,,C,C[O-].[Na+],test
US20120214803A1,Cc1cc(N)c2ncccc2c1.O=S(=O)(Cl)c1ccccc1>>Cc1cnc2c(NS(=O)(=O)c3ccccc3)cccc2c1,CN(C)c1ccncc1,,,CCCCCC,,test
US20050080105A1,COc1ccc(Cl)cc1C1=C(SCC2CO2)C(=O)NC2C=CC(C(F)(F)F)=CC12>>COc1ccc(Cl)cc1C1=C(SC=CCO)C(=O)NC2C=CC(C(F)(F)F)=CC12,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20140271543A1,COc1ncc(-c2cnn(Cc3ccccc3)c2)cc1[N+](=O)[O-]>>COc1ncc(-c2cnn(Cc3ccccc3)c2)cc1N,[Zn],CC(=O)O,,,,test
US20070191603A1,CCOC(=O)c1csc(N)n1.COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3nc(C(=O)O)cs3)cc21>>CCOC(=O)c1csc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cc(Cl)ccc2OC)CCO3)n1,,CN(C)C=O,Cc1ccccc1,O=S(Cl)Cl,,test
US04479942,CC(C)(C)OC(=O)NC(Cc1ccc(Cl)cc1)C(=O)O.COC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1N>>COC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1NC(=O)C(Cc1ccc(Cl)cc1)NC(=O)OC(C)(C)C,,C1CCOC1,O,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20080275052A1,Fc1ccc(-c2ncc3c(Cl)nccn23)c(F)c1>>Fc1ccc(-c2ncc3n2CCNC3)c(F)c1,[Pd],CO,,,,test
US20120309701A1,N.O=C(O)c1csc(Br)c1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>NC(=O)Nc1csc(Br)c1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20150322002A1,CC(C)CO.Clc1cc(Br)cnc1Cl>>CC(C)COc1ncc(Br)cc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20110039852A1,CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)OC)cc(C(F)(F)F)c1)C(=O)NC>>CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)cc(C(F)(F)F)c1)C(=O)NC,,C1COCCO1,,Cl,[Li+].[OH-],test
US20110275636A1,CC1(C)OC(=O)c2ccc(O)cc2O1.COCCOCCOS(=O)(=O)c1ccc(C)cc1>>COCCOCCOc1ccc2c(c1)OC(C)(C)OC2=O,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20100069629A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1c(F)cc(Br)cc1F>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1c(F)cc(Br)cc1F,CN(C)c1ccncc1,CN(C)C=O,,O,,test
US20130079313A1,CC(C)(C)OC(=O)N(c1ccc(C(=O)OC(C)(C)C(=O)O)cc1OCC1CC1)S(C)(=O)=O.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>CC(C)(C)OC(=O)N(c1ccc(C(=O)OC(C)(C)C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1OCC1CC1)S(C)(=O)=O,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20090311217A1,COc1ccc2[nH]c(C(=O)Cl)cc2c1.NC(=NO)C1CC1>>COc1ccc2[nH]c(-c3nc(C4CC4)no3)cc2c1,,ClC(Cl)Cl,,O,,test
US20160031879A1,O=CC1CCOC1.O=CC=P(c1ccccc1)(c1ccccc1)c1ccccc1>>O=C/C=C/C1CCOC1,,ClCCl,,,,test
US05840753,CCOC(=O)CCC(=O)[O-].CS(=O)(=O)c1ccc(C(=O)c2ccc(Cl)cc2)cc1>>CCOC(=O)/C(CC(=O)O)=C(\c1ccc(Cl)cc1)c1ccc(S(C)(=O)=O)cc1,,CCOCC,O,CC(C)(C)O,CC(C)(C)[O-].[K+],test
US20040009995A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CSc1sc(C(=N)N)cc1S(=O)(=O)c1cncc(Br)c1>>CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cncc(Br)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20060069132A1,CN1Cc2c(cccc2[N+](=O)[O-])C1=O>>CN1Cc2c(N)cccc2C1=O,[Pd],CCOC(C)=O,,,,test
US20150225354A1,CC(C)(C)OC(=O)CC1(C(=O)OC(C)(C)C)CC(c2cc(OCc3ccccc3)ccc2C2=CCCCC2)=NO1>>CC(C)(C)OC(=O)CC1(C(=O)OC(C)(C)C)CC(c2cc(O)ccc2C2CCCCC2)=NO1,[Pd],C1CCOC1,,,,test
US20030139423A1,COC(=O)Cl.CSc1cccc(C2=CCNCC2)c1>>COC(=O)N1CC=C(c2cccc(SC)c2)CC1,,ClCCl,,CCN(CC)CC,,test
US20160271130A1,CC(C)c1cc(Cl)nc(Cl)n1.Cc1ccc(N)cc1>>Cc1ccc(Nc2cc(C(C)C)nc(Cl)n2)cc1,,CC#N,,CCN(CC)CC,,test
US20120283216A1,C#Cc1ccc2ccc(OC(CC)C(=O)O)cc2c1.CC#CC(C)(C)N>>C#Cc1ccc2ccc(OC(CC)C(=O)NC(C)(C)C#CC)cc2c1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US04994479,CCN(CC)CC.CCN=C=O.Nc1ccc(OCC(=O)O)c(NC(=O)c2ccc(OCCCCc3ccccc3)cc2)c1>>CCNC(=O)Nc1ccc(OCC(=O)OCC)c(NC(=O)c2ccc(OCCCCc3ccccc3)cc2)c1,,ClCCl,,Cl,,test
US04197296,CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC=C[C@@]4(C)C[C@@H](N(C)C)[C@@H]32)C[C@@H]1O>>CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CCC[C@@]4(C)C[C@@H](N(C)C)[C@@H]32)C[C@@H]1O,[Pd],CCOC(C)=O,,,,test
US20070293515A1,Clc1ncnc2c1cnn2C1CCCCO1.N[C@H]1CC[C@@H](c2nc(-c3ccccc3)cs2)C1>>c1ccc(-c2csc([C@@H]3CC[C@H](Nc4ncnc5[nH]ncc45)C3)n2)cc1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20150018341A1,O=C(O)c1ccnc(Cl)c1.[OH-]>>O=C(O)c1cc[nH]c(=O)c1,,O,,Cl,,test
US20150175557A1,CC(C)c1ncncc1CNC(=O)OC(C)(C)C.Cl.ClCCl>>CC(C)c1ncncc1CN.Cl.Cl,,ClCCl,,,,test
US20060293311A1,COC(=O)C(C)(C)Oc1ccc([N+](=O)[O-])cc1>>CC(C)(Oc1ccc([N+](=O)[O-])cc1)C(=O)O,,CO,O,Cl,[Na+].[OH-],test
US20130085132A1,CC(=O)CCC(C)=O.Nc1cc[nH]n1>>Cc1ccc(C)n1-c1cc[nH]n1,,CC(=O)O,,O,,test
US20060020019A1,CC(CO)(CO)c1ccccc1.FC(F)(F)c1cc(CBr)cc(C(F)(F)F)c1>>CC(CO)(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US04212796,C[C@@H](OC(C)(C)C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](COC(C)(C)C)C(=O)O.Cl>>C[C@@H](OC(C)(C)C)[C@H](N)C(=O)N[C@@H](COC(C)(C)C)C(=O)O.Cl,,CO,,,,test
US20100240642A1,CC(C)(C)OC(=O)NS(=O)(=O)N1CCN(c2cccc(Cn3c(C(=O)OCc4ccccc4)c(-c4ccc(C(C)(C)C)cc4)c4ccccc43)c2)CC1>>CC(C)(C)c1ccc(-c2c(C(=O)O)n(Cc3cccc(N4CCN(S(N)(=O)=O)CC4)c3)c3ccccc23)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20160207905A1,Cc1cc(N)sn1.O=[N+]([O-])c1cccc(Nc2nc(Cl)ncc2Cl)c1>>Cc1cc(Nc2ncc(Cl)c(Nc3cccc([N+](=O)[O-])c3)n2)sn1,,C1COCCO1,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US04438128,CCOC(C)=O.O=C(O)/C=C/C(=O)O>>O.O=C(O)/C=C/C(=O)O,,CCOC(C)=O,,,,test
US20100216836A1,COc1cccc(OC)c1OC[C@H]1COC(C)(C)O1>>COc1cccc(OC)c1OC[C@H](O)CO,,CO,,,,test
US20050014812A1,CCCCCOc1ccc(Cn2c(C)nc3ccc(OCCCC(=O)OCC)cc32)c(Cl)c1>>CCCCCOc1ccc(Cn2c(C)nc3ccc(OCCCC(=O)O)cc32)c(Cl)c1,,CCO,,Cl,[Na+].[OH-],test
US20020128494A1,CC(=O)c1ccc(O)cc1O.CCBr>>COc1ccc(C(C)=O)c(O)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06432957B1,CC(C)(C)[Si](C)(C)Cl.COc1cc(-c2cc(CNCCO)ccn2)cc(OC)c1OC>>COc1cc(-c2cc(CNCCO[Si](C)(C)C(C)(C)C)ccn2)cc(OC)c1OC,CN(C)c1ccncc1,CC#N,,CCN(CC)CC,,test
US06352993B1,Cc1nc(Cl)nc(N2CCc3ccccc3C2C)c1C.NC1CCCC1>>Cc1nc(NC2CCCC2)nc(N2CCc3ccccc3C2C)c1C.Cl,,CN(C)C=O,,CCN(CC)CC,,test
US05208228,CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(O)C(OC(C)C)C3)C(C)C(O[Si](C)(C)C(C)(C)C)CC1=O)C(C)CC2OC.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(OS(=O)(=O)c4ccccc4[N+](=O)[O-])C(OC(C)C)C3)C(C)C(O[Si](C)(C)C(C)(C)C)CC1=O)C(C)CC2OC,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20120149910A1,Nc1ccc(C(=O)Nc2c(Cl)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2Cl)cc1.O=C1CCC(=O)N1Cl>>Nc1ccc(C(=O)Nc2c(Cl)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2Cl)cc1Cl,,O,,Cc1ccccc1,,test
US20140329820A1,CNN.Cn1nc2c(c1C1CC1)CN(C(=O)OC(C)(C)C)CC2>>Cn1nc(C2CC2)c2c1CCN(C(=O)OC(C)(C)C)C2,,CO,,,,test
US20050143588A1,CC(=O)Oc1ccc(C2=Cc3ccc(OC(C)=O)c(C)c3OC2)cc1>>C1=C(c2ccccc2)COc2ccccc21,,CCO,,c1c[nH]cn1,,test
US04036872,CCCOCC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=CC1CCC2(OCCO2)C1CCCCCCCO>>CCCOCC(=O)C=CC1CCC2(OCCO2)C1CCCCCCCO,,C1CCOC1,,,,test
US06492416B1,C#CC(C)(C)O.C1CCOC1.Cc1ccc(C=S)cc1>>CSc1ccc(C(O)C#CC(C)(C)O)cc1,,CCCCCC,,[Li]CCCC,,test
US20120295884A1,COc1cc2nn(COCC[Si](C)(C)C)c(C(C)=O)c2cc1OC>>COc1cc2[nH]nc(C(C)=O)c2cc1OC,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05192765,C=O.COc1ccc(CCNC(C)(C)CO)cc1>>COc1ccc(CCN(C)C(C)(C)CO)cc1,,O=CO,,Cl,,test
US20110224079A1,CCOC(=O)Cl.COCON1C(=O)C(c2cc(C)ccc2C)=C(O)C12CCN(OC)CC2>>CCOC(=O)OC1=C(c2cc(C)ccc2C)C(=O)N(OCOC)C12CCN(OC)CC2,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20160016948A1,CC(C)(C)OC(=O)N1C[C@H](F)[C@H](O)C(C)(C)C1>>CC1(C)CNC[C@H](F)[C@@H]1O,,ClCCl,,O=C(O)C(F)(F)F,,test
US03970701,CC/C=C\C(=O)C(OC)OC>>CC/C=C/C(=O)C(OC)OC,,CC(=O)O,,[I-].[Na+],,test
US20150073019A1,Cc1cccc(C2=NN(c3nc4ccccc4s3)C(=O)C2=CN(C)C)c1>>Cc1cccc(C2=NN(c3nc4ccccc4s3)C(=O)C2=CN)c1,,CO,N,,,test
US03959322,CCN(CC)CC#CCCCc1ccc(OC)c(OC)c1.O>>CCN(CC)CCC(=O)CCCc1ccc(OC)c(OC)c1,,O,O=S(=O)(O)O,[Na+].[OH-],,test
US20140099249A1,COC(=O)C(=O)OC.Cn1ccnc1>>COC(=O)C(=O)[O-].Cn1cc[n+](C)c1,,CC#N,,,,test
US20110105462A1,C=CCN.Cc1ccc(S(=O)(=O)OCC2COc3ccc(OS(C)(=O)=O)cc3O2)cc1>>C=CCNCC1COc2ccc(OS(C)(=O)=O)cc2O1,,CC#N,,,,test
US20050119256A1,COC(=O)[C@H](Cc1cc(I)c(O)c(I)c1)NC(=O)OC(C)(C)C.OCCCBr>>COC(=O)[C@H](Cc1cc(I)c(OCCCBr)c(I)c1)NC(=O)OC(C)(C)C,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130040945A1,CN(C)C(=O)Cl.COc1cc(C[C@H]2C(=O)OC[C@@H]2Cc2ccc(OC)c(OC)c2)ccc1O>>COc1ccc(C[C@H]2COC(=O)[C@@H]2Cc2ccc(OC(=O)N(C)C)c(OC)c2)cc1OC,CN(C)c1ccncc1,ClCCl,,[Cl-].[NH4+],,test
US07495007B2,C=C(C)C1NC(=O)CC(c2cc(Cl)ccc2N)C12C(=O)Nc1cc(Cl)ccc12.CS(=O)(=O)Cl>>C=C(C)C1NC(=O)CC(c2cc(Cl)ccc2NS(C)(=O)=O)C12C(=O)Nc1cc(Cl)ccc12,,CC#N,,c1ccncc1,,test
US20110136780A1,COC(=O)c1cn(C(=O)OC(C)(C)C)c2nccc(CN[C@@H](C(=O)O)C3CCCC3)c12.NC1CCCC1>>COC(=O)c1cn(C(=O)OC(C)(C)C)c2nccc(CN[C@@H](C(=O)NC3CCCC3)C3CCCC3)c12,,C1CCOC1,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080275067A1,Brc1ncnc2nc[nH]c12.CCC(N)c1nc2cccc(C)c2c(=O)n1-c1ccccc1>>CCC(Nc1ncnc2[nH]cnc12)c1nc2cccc(C)c2c(=O)n1-c1ccccc1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US06251911B1,CI.O=Cc1cccc(-c2nnn[nH]2)c1>>Cn1nnc(-c2cccc(C=O)c2)n1,,C1COCCO1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20130345221A1,Cc1sc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1C#N>>Cc1sc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1CN,,C1CCOC1,,Cl,,test
US05318964,CC(C)C[C@@H](C(=O)OCc1ccccc1)C(Cn1c(=O)n(C)n(C)c1=O)(C(=O)OCc1ccccc1)C(=O)OC(C)(C)C>>CC(C)C[C@@H](C(=O)O)C(Cn1c(=O)n(C)n(C)c1=O)(C(=O)O)C(=O)OC(C)(C)C,[Pd],CO,,,,test
US20160000760A1,CC(C)S(=O)(=O)c1ccc(B(O)O)cc1.Nc1nc(Nc2cc(F)c(Br)c(Cl)c2)n[nH]1>>CC(C)S(=O)(=O)c1ccc(-c2c(F)cc(Nc3n[nH]c(N)n3)cc2Cl)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20110201640A1,CCCC(=O)OC(=O)CCC.COC(=O)c1ccccc1N.O=[N+]([O-])O>>CCCC(=O)Nc1c(C(=O)OC)cccc1[N+](=O)[O-],,O,,[Na+].[OH-],,test
US05167691,CC(=O)OCC(=O)Nc1c([N+](=O)[O-])cnn1-c1c(F)c(F)c(C(F)(F)F)c(F)c1F>>O=C(CO)Nc1c([N+](=O)[O-])cnn1-c1c(F)c(F)c(C(F)(F)F)c(F)c1F,,CCO,O,Cl,[Na+].[OH-],test
US20150065468A1,COC(=O)c1cc(Br)cnc1Cl.NN>>Oc1n[nH]c2ncc(Br)cc12,,CCO,,,,test
US20070054942A1,CC(C)(C)OC(=O)N/N=C(/c1ccncc1)c1cc(F)c(Br)cc1F>>Fc1cc2c(-c3ccncc3)n[nH]c2cc1Br,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20100081671A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](O)CC1.Fc1cc2ccncc2cc1Cl>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](Oc2cc3ccncc3cc2Cl)CC1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20140093505A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.FC(F)(F)c1cncc(Br)c1>>CC1(C)OB(c2cncc(C(F)(F)F)c2)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US06495645B1,C=CC(=O)Cl.CC(N)CC(=O)OCc1ccccc1>>CC(C)C=C(C(N)=O)C(=O)OCc1ccccc1,,CCOCC,,CCN(CC)CC,Cc1ccc(S(=O)(=O)O)cc1,test
US04572914,Clc1ccc(C2=NNCC2c2ccccc2)cc1.O=C=Nc1ccc(OC(F)(F)C(F)F)cc1>>O=C(Nc1ccc(OC(F)(F)C(F)F)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1,,CCOCC,,,,test
US20120101103A1,CN(C)C(OC(C)(C)C)OC(C)(C)C.O=C(Nc1ccc2cc(Cl)ccc2n1)c1ccc(Oc2cc3c(cc2Cl)C(C(=O)O)CCO3)cc1>>CC(C)(C)OC(=O)C1CCOc2cc(Oc3ccc(C(=O)Nc4ccc5cc(Cl)ccc5n4)cc3)c(Cl)cc21,,CCOC(C)=O,Cc1ccccc1,,,test
US20060211603A1,CCOC(=O)Cc1csc(C2CCCCC2)n1>>O=C(O)Cc1csc(C2CCCCC2)n1,,CO,O,[Li]O,,test
US20160046581A1,CCOP(=O)(OCC)c1ccc2[nH]c([C@H](Cc3ccc(F)cc3)n3ccc(-c4cc(Cl)ccc4-n4cnnn4)cc3=O)nc2c1>>O=c1cc(-c2cc(Cl)ccc2-n2cnnn2)ccn1[C@@H](Cc1ccc(F)cc1)c1nc2cc(P(=O)(O)O)ccc2[nH]1,,ClCCl,,C[Si](C)(C)Br,,test
US20120220569A1,C=C[Sn](CCCC)(CCCC)CCCC.CCOC(=O)c1ccc(Br)cc1Cl>>C=Cc1ccc(C(=O)OCC)c(Cl)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,,,test
US20150018542A1,COC(=O)c1cc(F)ccc1O.O=C1CCC(=O)N1I>>COC(=O)c1cc(F)cc(I)c1O,,CN(C)C=O,,CCOC(C)=O,,test
US20060194859A1,COC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(-c2ccc(N)c(F)c2)cc1.Cc1ccc2nc(S(C)(=O)=O)oc2c1>>COC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(-c2ccc(Nc3nc4ccc(C)cc4o3)c(F)c2)cc1,,CC(Cl)Cl,,,,test
US20040077669A1,CC#CCOc1cc(Cl)ncn1.CCNCc1ccccc1>>CC#CCOc1cc(N(CC)Cc2ccccc2)ncn1,,CCO,,,,test
US20130296354A1,CC(C)(C)OC(=O)N1CCC2(CC1)CC1(Cc3cc(-c4ccc(S(C)(=O)=O)cc4)ncc3O1)C2.Cl>>CS(=O)(=O)c1ccc(-c2cc3c(cn2)OC2(C3)CC3(CCNCC3)C2)cc1.Cl,,C1COCCO1,,,,test
US20030114452A1,CS(=O)(=O)Cl.C[C@@H](CCO)NC(=O)OC(C)(C)C>>C[C@@H](CCOS(C)(=O)=O)NC(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US04999378,COC(=O)c1ccc(OCCCN(C(N)=O)c2ccc(Cl)cc2)cc1>>NC(=O)N(CCCOc1ccc(C(=O)O)cc1)c1ccc(Cl)cc1,,C1COCCO1,O,Cl,[Na+].[OH-],test
US05332717,COc1cc(OC)nc(Oc2cccc3c2C(=O)OC3O)n1.O=P(Cl)(Cl)Cl>>COc1cc(OC)nc(Oc2cccc3c2C(=O)OC3Cl)n1,,O,,,,test
US20120190680A1,NCC1(c2cccnc2)CCCCC1.O=C(O)c1cn(-c2ncccn2)c2nccc(Cl)c12>>O=C(NCC1(c2cccnc2)CCCCC1)c1cn(-c2ncccn2)c2nccc(Cl)c12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20020147205A1,FC(F)(F)c1cc(Nc2ncnc3ccc(-c4ccc(C5OCCO5)o4)cc23)ccc1OCc1ccccc1>>O=Cc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5ccccc5)c(C(F)(F)F)c4)c3c2)o1,,C1CCOC1,,Cl,O,test
US20080153814A1,CC1=NN=C(c2ccc([N+](=O)[O-])c(C)c2)c2cc(Cl)ccc2C1.O=C(Cl)Oc1ccccc1>>CC1=Cc2ccc(Cl)cc2C(c2ccc([N+](=O)[O-])c(C)c2)=NN1C(=O)Oc1ccccc1,,C1CCCCC1,,CCN(CC)CC,,test
US20130040930A1,COC(=O)c1ccc(C(C)(C)N)cc1.CS(=O)(=O)Cl>>COC(=O)c1ccc(C(C)(C)NS(C)(=O)=O)cc1,,ClCCl,,CCN(CC)CC,,test
US20030149033A1,COc1ccc(CC(=O)Cl)cc1.NC(=O)c1onc(C2CCCC2)c1N>>COc1ccc(CC(=O)Nc2c(C3CCCC3)noc2C(N)=O)cc1,CN(C)c1ccncc1,c1ccncc1,,,,test
US06235771B1,COCCCl.Oc1ccc(Br)cc1>>COCCOc1ccc(Br)cc1,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US05043482,CC(C)(Cl)CCC(C)(C)Cl.COc1ccc(OC)cc1>>COc1ccc(OC)c2c1C(C)(C)CCC2(C)C,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100216788A1,Nc1cnc(Oc2cccc(OC(F)(F)F)c2)c(Cl)c1.O=C(OCCn1ccc2ncnc(Cl)c21)c1ccccc1>>OCCn1ccc2ncnc(Nc3cnc(Oc4cccc(OC(F)(F)F)c4)c(Cl)c3)c21,,CC(C)O,,O,[Na+].[OH-],test
US06756388B1,CS(=O)(=O)Oc1ccc(-c2sc3cc(OS(C)(=O)=O)ccc3c2C(=O)c2ccc(OCCN3CC4CCC3C4)cc2)cc1>>O=C(c1ccc(OCCN2CC3CCC2C3)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04495202,COc1ccc(C2=CC(c3ccc(F)cc3)=CCC2c2ccc(OC)cc2)cc1>>COc1ccc(-c2ccc(-c3ccc(F)cc3)cc2-c2ccc(OC)cc2)cc1,,Cc1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US04767766,CI.COc1cccc(CSc2ncccc2C(=O)O)c1>>COC(=O)c1cccnc1SCc1cccc(OC)c1,,CC#N,,,,test
US20140242135A1,CCN=C=S.NNC(=O)c1ccncc1>>CCn1c(S)nnc1-c1ccncc1,,CCO,CO,O,O=C([O-])[O-].[K+].[K+],test
US20160000760A1,CC(C)CS(=O)(=O)c1ccc(B(O)O)cc1.Nc1nc(Nc2cc(Cl)c(Br)c(C(F)(F)F)c2)n[nH]1>>CC(C)CS(=O)(=O)c1ccc(-c2c(Cl)cc(Nc3n[nH]c(N)n3)cc2C(F)(F)F)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20070219186A1,Cc1cc(-c2cccc(N)c2)n2nc(-c3ccncc3)cc2n1.O=C(Cl)c1cccc(C(F)(F)F)c1>>Cc1cc(-c2cccc(NC(=O)c3cccc(C(F)(F)F)c3)c2)n2nc(-c3ccncc3)cc2n1,,c1ccncc1,,,,test
US20150238601A1,CC(=O)c1ccc(-c2nccc(Nc3ccc4c(cnn4C(=O)OC(C)(C)C)c3)n2)cc1.[NH4+]>>CC(N)c1ccc(-c2nccc(Nc3ccc4c(cnn4C(=O)OC(C)(C)C)c3)n2)cc1,,CO,,[BH3-]C#N.[Na+],,test
US20100215616A1,CC(C)[C@H](N)C(=O)OC(C)(C)C.COC(=O)Cl>>COC(=O)N[C@H](C(=O)OC(C)(C)C)C(C)C,,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US04168317,N.c1cc(OCC2CO2)c2cnsc2c1>>NCC(O)COc1cccc2sncc12,,CCO,,,,test
US05633384,CSc1ccccc1C#N.O=S(=O)(Cl)Cl>>O=c1[nH]sc2ccccc12,,Clc1ccccc1,,O,,test
US20080255202A1,Cc1cccc(CC(=O)Cl)c1.N>>Cc1cccc(CC(N)=O)c1,,C1COCCO1,,Cl,,test
US06127343,BrCc1ccc(Br)cc1.NCCCNc1ccc2ccccc2n1>>NCCCN(Cc1ccc(Br)cc1)c1ccc2ccccc2n1,,CS(C)=O,,[H-].[Na+],,test
US20100016401A1,CC(C)(C)OC(=O)N1C[C@H]2C[C@H]2[C@H]1CNCc1ccccc1>>CC(C)(C)OC(=O)N1C[C@H]2C[C@H]2[C@H]1CN,[Pd],CCO,,,,test
US20100197711A1,CC(=O)c1ccc(-c2cccc(S(N)(=O)=O)c2)o1.Clc1ncccn1>>NS(=O)(=O)c1ncccn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070179165A1,CCCC(CCC)N/C=C(\C#N)C(=O)c1c(Cl)cccc1Cl>>CCCC(CCC)n1cc(C#N)c(=O)c2c(Cl)cccc21,,C1COCCO1,,[H-].[Na+],,test
US20080139549A1,C1COCCN1.CCOC(=O)c1cc2cc(Cl)cc(CBr)c2n1C(=O)OC(C)(C)C>>CCOC(=O)c1cc2cc(Cl)cc(CN3CCOCC3)c2[nH]1,,C1CCOC1,,,,test
US05700804,CC(=O)N1CC(=O)N(C(C)=O)CC1=O.O=Cc1cccc([N+](=O)[O-])c1>>CC(=O)N1CC(=O)NC(=Cc2cccc([N+](=O)[O-])c2)C1=O,,CN(C)C=O,,CCN(CC)CC,,test
US20140038926A1,FC(F)(F)c1cc(Cl)ccn1.SCc1ccccc1>>FC(F)(F)c1cc(SCc2ccccc2)ccn1,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20150291593A1,COC(=O)c1c(Cl)ccn1CC(C)=O.N>>Cc1cn2ccc(Cl)c2c(=O)[nH]1,,CO,,,,test
US04670043,CC(C)Oc1cc(-n2[nH]c3c(c2=O)CCCC3)c(F)cc1Cl.O=P(Cl)(Cl)Cl>>CC(C)Oc1cc(-n2nc3c(c2Cl)CCCC3)c(F)cc1Cl,,ClC(Cl)Cl,,,,test
US06313127B1,N#Cc1ccc(C(=O)Cl)cc1.c1cc(N2CCNCC2)ccn1>>N#Cc1ccc(C(=O)N2CCN(c3ccncc3)CC2)cc1,,CCN(CC)CC,ClCCl,,,test
US20060089349A1,CNc1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1.O=C(Cl)CCl>>CN(C(=O)CCl)c1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1,,C1CCOC1,,,,test
US20110269742A1,CC(C)(C)OC(=O)N1CC(c2ncc[nH]2)C1>>c1c[nH]c(C2CNC2)n1,,ClCCl,,,,test
US20090317869A1,C[Si](C)(C)C=[N+]=[N-].O=C(O)C(=O)[C@@H](O)[C@H](O)[C@H](O)CO.[CH2-]C(C)=O.[CH2-]C(C)=O>>O=C(O)CC(=O)[C@@H](O)[C@H](O)[C@H](O)CO.[CH2-]C(C)=O.[CH2-]C(C)=O,,CO,,CCOCC,,test
US06255333B1,C=C[Sn](CCCC)(CCCC)CCCC.Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)cc1I>>C=Cc1cn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)nc1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US20100137303A1,CCNC(=O)Nc1nc2cc(Br)c(OCCOC)nc2s1.OB(O)c1cncnc1>>CCNC(=O)Nc1nc2cc(-c3cncnc3)c(OCCOC)nc2s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])O.[Na+],,test
US20110301143A1,CCOC(=O)Cn1nnc(-c2cnc(N3CCC(c4ccc(Cl)cc4)CC3)s2)n1>>O=C(O)Cn1nnc(-c2cnc(N3CCC(c4ccc(Cl)cc4)CC3)s2)n1,,C1CCOC1,,CC(=O)O,[Li+].[OH-],test
US04243609,CCCCCCCCCCCCCCCCNc1ccc(C(=O)O)c(F)c1.ClC(Cl)Cl.O=C(Cl)OCc1ccccc1>>CCCCCCCCCCCCCCCCN(C(=O)OCc1ccccc1)c1ccc(C(=O)Cl)c(F)c1,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20080004309A1,CCOC(=O)C(Cl)C(C)=O.COc1cccc(C(N)=S)c1>>CCOC(=O)c1sc(-c2cccc(OC)c2)nc1C,,CCO,,,,test
US20120115864A1,CCCn1c(Cl)nc2nc(-c3cnn(Cc4ccccc4)c3)[nH]c2c1=O.NCc1ccc(C(F)(F)F)cc1>>CCCn1c(NC)nc2nc(-c3cnn(Cc4ccccc4)c3)[nH]c2c1=O,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US20160244415A1,CCOC(=O)c1cn(-c2ccc(N3CCNC3=O)cc2)c(=O)[nH]c1=O.Cc1c(CBr)cccc1C(F)(F)F>>CCOC(=O)c1cn(-c2ccc(N3CCNC3=O)cc2)c(=O)n(Cc2cccc(C(F)(F)F)c2C)c1=O,,CC#N,O,[I-].[K+],,test
US20020006943A1,BrCc1ccccc1.CCOC(=O)C(C(=O)OCC)C(=O)c1ccc[nH]1>>CCOC(=O)C(Cc1ccccc1)(C(=O)OCC)C(=O)c1ccc[nH]1,,CCOC(C)=O,COCCOC,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20050059729A1,O=C(O)CCCc1ccc(F)cc1>>O=C1CCCc2ccc(F)cc21,,O,,,,test
US20050009840A1,COC(=O)c1ccc(-c2cnc(N)c(OCc3ccccc3)c2)cc1>>COC(=O)c1ccc(-c2cnc(N)c(O)c2)cc1,[Pd],CCO,O,,,test
US20160016880A1,BrC(Br)(Br)Br.OCc1cc(F)cc(Oc2ccccc2)c1>>Fc1cc(CBr)cc(Oc2ccccc2)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090137601A1,COC(=O)[C@H](Cc1ccc(C2CCNCC2)cc1)NC(=O)c1c(Cl)cccc1Cl.O=C(O)c1cnccn1>>O=C(N[C@@H](Cc1ccc(C2CCN(C(=O)c3cnccn3)CC2)cc1)C(=O)O)c1c(Cl)cccc1Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060004003A1,CCOC(=O)CCc1c(C=O)nc2c(cnn2CC)c1-c1cncc(C)c1.[C-]#[N+]C(C)S(=O)(=O)c1ccc(C)cc1>>CCn1ncc2c(-c3cncc(C)c3)c(CCC(=O)O)c(-c3ocnc3C)nc21,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20150315160A1,CC(C)(C)OC(=O)Nc1conc1-c1ccc(O)cc1.OCc1cccnc1>>CC(C)(C)OC(=O)Nc1conc1-c1ccc(OCc2cccnc2)cc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020016365A1,CCOC(=O)C(O)(CC(C)(C)c1ccc(OC)cc1)C(F)(F)F.O=C1CCC(=O)N1Br>>COc1ccc(C(C)(C)CC(O)(C(=O)O)C(F)(F)F)cc1Br,,CN(C)C=O,,,,test
US20100234351A1,CC(C)(C)OC(=O)NCCOCCS(C)(=O)=O.Cl>>CS(=O)(=O)CCOCCN.Cl,,C1CCOC1,,,,test
US20030018045A1,COc1cc(OCCCOc2ccccc2)ccc1CCNC(=O)N1CCC(Nc2ccc(CCNC[C@H](O)COc3ccc(O[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)cc3)cc2)CC1>>COc1cc(OCCCOc2ccccc2)ccc1CCNC(=O)N1CCC(Nc2ccc(CCNC[C@H](O)COc3ccc(O)cc3)cc2)CC1,,CO,ClC(Cl)Cl,,,test
US04426382,C/C=C/C(=O)N1CCNCC1.CC(C)CCO.COc1cc2nc(Cl)nc(N)c2cc1OC>>C/C=C/C(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1.Cl.O,,CC(C)CCO,,,,test
US20160089374A1,FC(F)(F)c1cccc(-c2nc(Cl)nc(Cl)n2)n1.Nc1ccnc(C(F)(F)F)c1>>FC(F)(F)c1cc(Nc2nc(Cl)nc(-c3cccc(C(F)(F)F)n3)n2)ccn1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20060166989A1,COC(=O)C(N)Cc1ccccc1.O=C(O)c1ccc2cc(O)ccc2c1>>COC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc2cc(O)ccc2c1,,CCN(CC)CC,CN(C)C=O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US05834493,CCOC(=O)Cl.COc1ccc2[nH]cc(CC3=CCCN(Cc4ccccc4)C3)c2c1>>CCOC(=O)N1CCC=C(Cc2c[nH]c3ccc(OC)cc23)C1,,Cc1ccccc1,,,,test
US20100016387A1,Cc1cccc(C)c1-c1nc2ccc(CO)cc2[nH]1>>Cc1cccc(C)c1-c1nc2ccc(C=O)cc2[nH]1,O=[Mn]=O,C1CCOC1,,,,test
US20080318929A1,CC(C)(C)OC(=O)NCC(=O)Nc1cccc(CNC(=O)C(F)(F)F)c1>>CC(C)(C)OC(=O)NCC(=O)Nc1cccc(CN)c1,,CO,,[Na+].[OH-],,test
US06288100B1,CCCCCCBr.COc1cc(C#N)ccc1O>>CCCCCCOc1ccc(C#N)cc1OC,,CN(C)C=O,,[H-].[Na+],,test
US20160115159A1,COc1ccc(Br)cc1[C@H](C)CO>>COc1ccc(Br)cc1[C@H](C)C=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20080311076A1,CNc1ccc(N2CCOCC2)cc1.Clc1ncnc2ccc(I)cc12>>CN(c1ccc(N2CCOCC2)cc1)c1ncnc2ccc(I)cc12,,CC#N,,,,test
US06630488B1,CCOC(=O)CC(N)c1ccccc1.CN(C)C=O.CN1CCOCC1.O=C(O)c1ccc2cc(Cl)ccn2c1=O>>NCCNc1ccn2c(=O)c(C(=O)NC(CC(=O)O)c3ccccc3)ccc2c1,,CN(C)C=O,,Cl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030162967A1,CCOC(=O)c1cc(O)c(Br)c(O)c1.OCCc1ccc(Cl)cc1Cl>>CCOC(=O)c1cc(O)c(Br)c(OCCc2ccc(Cl)cc2Cl)c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020045747A1,CC(C)CO.CC(C)C[C@H](NC(=O)Cc1ccccc1)C(=O)O>>CC(C)COC(=O)[C@H](CC(C)C)NC(=O)Cc1ccccc1,,ClC(Cl)Cl,,,,test
US20080119518A1,C=CCc1c(CO)cccc1OC.CC(C)(C)[Si](C)(C)Cl>>C=CCc1cccc(O[Si](C)(C)C(C)(C)C)c1OC,,CN(C)C=O,,O,c1c[nH]cn1,test
US20140348748A1,CC(C)(C)C(=O)Nc1ccc(C=O)nc1Cl.COc1ccc(N)c(S)c1>>COc1ccc2nc(-c3ccc(NC(=O)C(C)(C)C)c(Cl)n3)sc2c1,,CS(C)=O,,CCOC(C)=O,,test
US20040039019A1,N#CCn1ncc2ccc(N)cc21.O=C(Nc1ccc2cn[nH]c2c1)c1ccccc1NCc1ccc(=O)[nH]c1>>N#CCn1ncc2ccc(NC(=O)c3ccccc3NCc3ccc(=O)[nH]c3)cc21,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04440788,CCCCOC(=O)N[C@@H](CSC)C(=O)NCC.Cl>>CCNC(=O)[C@@H](N)CSC.Cl,,CCOC(C)=O,,,,test
US04128648,COc1cc(C)c(C=C2COCC(=Cc3cc(C)c(OC)cc3C)C2=O)cc1C.NC1=NCCS1>>COc1cc(C)c(C=C2COCC3=C2N=C2SCCN2C3c2cc(C)c(OC)cc2C)cc1C,,CCO,ClC(Cl)Cl,,,test
US20040248225A1,CC(C)(C)OC(=O)NNC(=O)C1N=C(c2nc3ccc(O)cc3s2)SC1(C)C>>CC1(C)SC(c2nc3ccc(O)cc3s2)=NC1C(=O)NN,,C1CCOC1,,O=C(O)C(F)(F)F,,test
US20160083377A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc(CNc2ccc3c(n2)OCC(=O)N3c2ccc(Cl)cc2)c(OC)c1>>COc1ccc(CN(C(=O)OC(C)(C)C)c2ccc3c(n2)OCC(=O)N3c2ccc(Cl)cc2)c(OC)c1,CN(C)c1ccncc1,C1COCCO1,,O,,test
US20140163229A1,CC(C)[Si](O)(c1cccc(C(=O)N2CCC(c3cccc(CNC(=O)C(F)(F)F)c3)CC2)c1)C(C)C>>CC(C)[Si](O)(c1cccc(C(=O)N2CCC(c3cccc(CN)c3)CC2)c1)C(C)C,,CO,,[K+].[OH-],,test
US20140005184A1,CC(CO)C1(N)CCC1.CCOC(OCC)OCC.O=C([O-])CC(=O)c1cc(F)c(F)c(F)c1F>>CCOC(=O)C(=CNC1(C(C)CO)CCC1)C(=O)c1cc(F)c(F)c(F)c1F,,Cc1ccccc1,,CC(=O)OC(C)=O,,test
US20050130989A1,CCOC(=O)c1cccc(N2CCN(C(=O)c3cc(C)nn3-c3ccccc3)CC2)c1>>Cc1cc(C(=O)N2CCN(c3cccc(C(=O)O)c3)CC2)n(-c2ccccc2)n1,,CO,O,[K+].[OH-],,test
US06323235B1,COC(=O)C(C)Oc1cccc2c(CCBr)coc12.SCCc1ccccc1>>COC(=O)COc1cccc2c(CCSCCc3ccccc3)c(C)oc12,,CN(C)C=O,O,CC(=O)O,[H-].[Na+],test
US04268591,CCCCCCCCCCCCCCCCNc1ccccc1[N+](=O)[O-].O=C(Cl)c1ccc(Cl)c([N+](=O)[O-])c1>>CCCCCCCCCCCCCCCCN(C(=O)c1ccc(Cl)c([N+](=O)[O-])c1)c1ccccc1[N+](=O)[O-],,c1ccccc1,,CCCCCC,,test
US20080090813A1,CSc1nc(O)cc(CCCOCc2ccccc2)n1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CSc1nc(CCCOCc2ccccc2)cc(OC(=O)C(F)(F)F)n1,,ClCCl,,CCN(CC)CC,,test
US06242474B1,COC(=O)/C=C/c1c(Br)nc(C)n1Cc1ccc(Cl)cc1Cl>>Cc1nc(Br)c(/C=C/C(=O)O)n1Cc1ccc(Cl)cc1Cl,,CO,,Cl,[Na+].[OH-],test
US20030008872A1,Fc1cccc(-c2cc3ccc(OC(F)F)nn3n2)c1.O=C1CCC(=O)N1Br>>Fc1cccc(-c2nn3nc(OC(F)F)ccc3c2Br)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])O.[Na+],,test
US05519034,Br.COc1ccc2c(c1)C(C1(c3ccccc3Cl)CC1)N(C)CC2>>Br.CN1CCc2ccc(O)cc2C1C1(c2ccccc2Cl)CC1,,CC(=O)O,,,,test
US04254135,CCN1CC(O)C(N(C(=O)c2ccc(Cl)cc2)C2CCCCC2)C1>>CCN1C[C@@H](N(C(=O)c2ccc(Cl)cc2)C2CCCCC2)[C@H](O)C1,,CO,,O,[K+].[OH-],test
US20160075711A1,ClCCl.O=S(=O)(O)C1CCC(F)(CCC2c3ccccc3-c3cncn32)CC1>>O=S(=O)(Cl)C1CCC(F)(CCC2c3ccccc3-c3cncn32)CC1,CN(C)C=O,,,,,test
US20160084859A1,CCOC(=O)CCCCBr.O=C(O)c1n[nH]c2ccccc12>>CCOC(=O)CCCCn1nc(C(=O)O)c2ccccc21,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4cccs4)nc(Cl)c3n2)cc1.Nc1cccc(S(=O)(=O)CCO)c1>>O=S(=O)(CCO)c1cccc(Nc2nc(-c3cccs3)nc3cn[nH]c23)c1,C1COCCO1,CO,,Cl,,test
US05278175,CCc1ncnc(Cl)c1Cl.O=C(Cn1cncn1)c1ccc(F)cc1F>>CC(c1ncnc(Cl)c1Cl)C(O)(Cn1cncn1)c1ccc(F)cc1F,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20130123230A1,CC(=O)Cl.COc1ccc(-c2cc(=O)[nH]c(=S)n2CC(=O)NCCNC(=O)OC(C)(C)C)c(OC)c1>>COc1ccc(-c2cc(=O)[nH]c(=S)n2CC(=O)NCCN)c(OC)c1.Cl,,CCO,,,,test
US20140235614A1,COC(=O)c1ccc(C2CCN(C(=O)OC(C)(C)C)CC2O)cc1.COCCN(CCOC)S(F)(F)F>>COC(=O)c1ccc(C2CCN(C(=O)OC(C)(C)C)CC2F)cc1,,ClCCl,,CCOC(C)=O,O=C([O-])O.[Na+],test
US20120214803A1,CN(C)CCO.O=S1(=O)Nc2c(cc(Cl)c3cccnc23)-c2cc(F)ccc21>>CN(C)CCOc1ccc2c(c1)-c1cc(Cl)c3cccnc3c1NS2(=O)=O,,CN1CCCC1=O,,[H-].[Na+],,test
US20050054640A1,CC(=O)Cl.CCc1nc2c(N)nc3ccccc3c2n1NCCCN>>CCc1nc2c(N)nc3ccccc3c2n1NCCCNC(C)=O,,CO,ClCCl,CCN(CC)CC,Cl,test
US20110015157A1,N#CSCC(=O)c1ccccc1>>O=c1[nH]c(-c2ccccc2)cs1,,CC(=O)O,,O,O=S(=O)(O)O,test
US20020123502A1,Br.C=CC(=O)OCC.CCc1nc(C)cc(=O)n1CCOc1ccc(N)cc1>>CCOC(=O)C(Br)Cc1ccc(OCCn2c(CC)nc(C)cc2=O)cc1,[Cu]I,CC(C)=O,O,O=N[O-].[Na+],,test
US20100190761A1,CC(=O)OCC(=O)O/N=C(/N)c1ccc(C(C)(c2ccc(OCc3ccccn3)cc2)C(C)C)cc1>>CC(=O)OCc1nc(-c2ccc(C(C)(c3ccc(OCc4ccccn4)cc3)C(C)C)cc2)no1,,Cc1ccccc1C,,,,test
US04814332,C[O+](C)C.Cc1nccn1N=Cc1ccccc1.F[B-](F)(F)F>>Cc1n(C)cc[n+]1N=Cc1ccccc1.F[B-](F)(F)F,,ClCCl,,,,test
US03931173,NCc1cccnc1.O=C(O)C1Oc2ccc(Cl)cc2Cc2cc(Cl)ccc2O1>>O=C(NCc1cccnc1)C1Oc2ccc(Cl)cc2Cc2cc(Cl)ccc2O1,,c1ccccc1,,O=S(Cl)Cl,,test
US04634704,CN=C=O.Fc1ccc(Cn2c(NC3CCN(CCNc4nccs4)CC3)nc3ccccc32)cc1>>CNC(=O)N(CCN1CCC(Nc2nc3ccccc3n2Cc2ccc(F)cc2)CC1)c1nccs1,,C1CCOC1,,,,test
US20120214803A1,Clc1cnccn1.SCc1ccccc1>>c1ccc(CSc2cnccn2)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110059943A1,CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(N=C=S)nc21.Cc1cc(N)n(C)n1>>CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(NC(=S)Nc3cc(C)nn3C)nc21,,CCOC(C)=O,,C1CCOC1,[H-].[Na+],test
US05340812,C=C(C(=O)O)c1ccccc1.c1ccc(N2CCNCC2)cc1>>O=C(O)C(CN1CCN(c2ccccc2)CC1)c1ccccc1,,CCO,,,,test
US20110237596A1,Clc1ccc(Oc2cccc(CN3CCNCC3)c2)cc1.O=C(Nc1cnc2cccnn12)Oc1ccccc1>>O=C(Nc1cnc2cccnn12)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1,,CCOC(C)=O,CS(C)=O,CCN(C(C)C)C(C)C,Cl,test
US20130005716A1,CCOC(=O)CC1NCCS1.O=S(=O)(Cl)c1ccccc1>>CCOC(=O)CC1SCCN1S(=O)(=O)c1ccccc1,,c1ccncc1,,,,test
US20140155375A1,CC(=O)N1c2cc(Br)c(F)cc2C(=O)C1C.CI>>CC(=O)N1c2cc(Br)c(F)cc2C(=O)C1(C)C,,C1CCOC1,,[H-].[Na+],,test
US20130116250A1,CCCN.Cc1nc2ccc(C(=O)c3nc(Br)c4ccccn34)cc2c(=O)o1>>CCCn1c(C)nc2ccc(C(=O)c3nc(Br)c4ccccn34)cc2c1=O,,CC(=O)O,,O=C([O-])[O-].[Na+].[Na+],,test
US20110237584A1,C[Si](C)(C)C(F)(F)F.Cn1cc(C=O)cn1>>Cn1cc(C(O)C(F)(F)F)cn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120270852A1,CC(C)(C)NC(=O)c1ccc(C#Cc2ccccc2)cn1.CI>>CN(C(=O)c1ccc(C#Cc2ccccc2)cn1)C(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20100324045A1,C=C(C)CC(CCN(C(=O)OC(C)(C)C)[C@@H](C)c1ccc(Br)cc1)(N[S@](=O)C(C)(C)C)c1ccccc1>>C=C(C)CC(N)(CCN[C@@H](C)c1ccc(Br)cc1)c1ccccc1,,C1COCCO1,Cl,O=C([O-])[O-].[Na+].[Na+],,test
US20160096835A1,NNc1ccc(S(=O)(=O)c2ccccc2)cn1.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]nc2ccc(S(=O)(=O)c3ccccc3)cn12,,CC(Cl)Cl,,,,test
US20100185419A1,C=CC(=O)Nc1ccc(C(=O)OC)cc1[N+](=O)[O-]>>C=CC(=O)Nc1ccc(C(=O)O)cc1[N+](=O)[O-],,C1CCOC1,,Cl,[Li+].[OH-],test
US20100331293A1,Cc1c(Cl)nc2cc(F)cc(F)c2c1Cl.OB(O)c1cncc(Cl)c1>>Cc1c(-c2cncc(Cl)c2)nc2cc(F)cc(F)c2c1Cl,,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20090239845A1,Cc1cc(C(=O)O)nn1Cc1cc(Cl)ccc1OCc1ccccc1.Nc1cccnc1N.O=P(Cl)(Cl)Cl>>Cc1cc(-c2nc3ncccc3[nH]2)nn1Cc1cc(Cl)ccc1OCc1ccccc1.Cl,,O=P(Cl)(Cl)Cl,,,,test
US20070281979A1,Brc1ccsc1Br.COCCOS(=O)(=O)c1ccc(C)cc1>>COCCc1sccc1Br,,C1CCOC1,,[Li]CCCC,,test
US20090111794A1,CC(=O)OC(C)=O.c1ccc2sc(Oc3ccc(CN4C[C@@H]5C[C@H]4CN5)cc3)nc2c1>>CC(=O)N1C[C@@H]2C[C@H]1CN2Cc1ccc(Oc2nc3ccccc3s2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20160060237A1,CC(C)CN(CC(C)C)c1ccc(C(=O)C(F)(F)F)cc1[N+](=O)[O-].CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)C=C(c1ccc(N(CC(C)C)CC(C)C)c([N+](=O)[O-])c1)C(F)(F)F,,C1CCOC1,,[H-].[Na+],,test
US20020091131A1,CCC(C)[C@H](N)C(=O)c1ccccc1>>CCC(C)[C@H](N)[C@H](O)c1ccccc1,,CO,,Cl,[BH4-].[Na+],test
US20150094474A1,CCOC(=O)C(C)Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1>>CC(CO)Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070197532A1,CC(C)Cn1cnc2ccc(Br)cc21.OB(O)c1ccn[nH]1>>CC(C)Cn1cnc2ccc(-c3ccn[nH]3)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20150361125A1,BrCc1ccccc1.CC=C1C[C@@H]2[C@H]3CC[C@@H]4C[C@@H](O)CC[C@@]4(C)[C@@H]3CC[C@@]2(C)C1>>CC=C1C[C@@H]2[C@H]3CC[C@@H]4C[C@@H](OCc5ccccc5)CC[C@@]4(C)[C@@H]3CC[C@@]2(C)C1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20090099164A1,CNCC(O)C(c1ccc(OC(F)(F)F)cc1)n1ccc2ccccc21.Cl>>CNC[C@@H](O)[C@H](c1ccc(OC(F)(F)F)cc1)n1ccc2ccccc21.Cl,,CO,,,,test
US20090012054A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cn1ncc(C(O)CC#N)c1NC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cn1ncc(C(O)CCNC(=O)OC(C)(C)C)c1NC(c1ccccc1)(c1ccccc1)c1ccccc1,O=[Pt],CCO,,,,test
US20050085508A1,B1C2CCCC1CCC2.C1CCOC1.CCO.OO>>O=C1CC2(CCOCC2)CCO1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20130303524A1,CC(C)CBr.CS(=O)(=O)NCc1ccco1>>C=C(C)CN(Cc1ccco1)S(C)(=O)=O,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20040138485A1,C[Si](C)(C)O[C@H]1C=C(S(=O)(=O)c2ccccc2)C=CCC1.[Li]C.c1ccc(SSc2ccccc2)cc1>>C[C@H]1C(S(=O)(=O)c2ccccc2)C=C(Sc2ccccc2)CC[C@H]1O[Si](C)(C)C,,C1CCOC1,,,,test
US04353827,COc1cccc2[nH]c(=O)oc(=O)c12.O=C(O)[C@@H]1CCCN1>>COc1cccc2c1C(=O)N1CCC[C@H]1C(=O)N2,,CS(C)=O,,,,test
US20080255083A1,CN(C)C(=O)C1CCNCC1.O=c1cc(O)ccn1CCc1ccc(CBr)cc1>>CN(C)C(=O)C1CCN(Cc2ccc(CCn3ccc(O)cc3=O)cc2)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US04533664,CN1C(C(=O)Cl)=C(O)c2ccccc2S1(=O)=O.Nc1cncc(Cl)n1>>CN1C(C(=O)Nc2cncc(Cl)n2)=C(O)c2ccccc2S1(=O)=O,,CN(C)C=O,,O,,test
US20150315197A1,CC(C)(C)OC(=O)N1CC=C(c2cccc(Cl)c2C(F)(F)F)CC1>>CC(C)(C)OC(=O)N1CCC(c2cccc(Cl)c2C(F)(F)F)CC1,O=[Pt],CCOC(C)=O,,CC(=O)O,,test
US20020173518A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)c1ccc(C(=O)Nc2ccc([N+](=O)[O-])cc2C(=O)Nc2ccc3cn[nH]c3c2)cc1>>CC(C)(C)OC(=O)n1ncc2ccc(NC(=O)c3cc([N+](=O)[O-])ccc3NC(=O)c3ccc(C(C)(C)C)cc3)cc21,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20100168094A1,COC(=O)Cl.Cc1cc(Br)ccc1O>>COC(=O)Oc1ccc(Br)cc1C,,ClCCl,,CCN(CC)CC,,test
US20040122244A1,CC(=O)Oc1ccc(CC2=C(C)C(=O)C(C)=C(C)C2=O)cc1C(=O)O.Nc1ccncc1>>CC1=C(C)C(=O)C(Cc2ccc(O)c(C(=O)Nc3ccncc3)c2)=C(C)C1=O,,ClCCl,O,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US20160075711A1,CCOC(=O)C1(F)CCC(F)(F)CC1.COP(C)(=O)OC>>COP(=O)(CC(=O)C1(F)CCC(F)(F)CC1)OC,,C1CCOC1,,[Li]CCCC,,test
US20070129313A1,CCc1cccc2ccccc12.O=S(=O)(O)Cl>>CCc1ccc(S(=O)(=O)Cl)c2ccccc12,,O,,O=C(O)C(F)(F)F,,test
US20070197542A1,COC(=O)C1CCOCC1.CS(=O)(=O)N1CCN(c2ccc(OC(F)(F)C(F)F)cc2)CC1>>O=C(CS(=O)(=O)N1CCN(c2ccc(OC(F)(F)C(F)F)cc2)CC1)C1CCOCC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20080027077A1,Brc1ccc(Br)nc1.CNc1cccc(B(O)O)c1>>NCc1cccc(-c2ccc(Br)cn2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,CN(C)C=O,O,test
US20060235033A1,COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1N.C[C@@H](N)c1cccc(Br)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)N[C@H](C)c1cccc(Br)c1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US04863958,BrBr.CCCc1ccc2oc(Cc3ccc(OC)cc3)c(C)c2c1O>>CCCc1cc(Br)c2oc(Cc3ccc(OC)cc3)c(C)c2c1O,,ClCCl,,,,test
US20150038485A1,Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1.O[C@H]1CCNC1>>O[C@H]1CCN(c2ccc3ncc(-c4cc5ccccc5o4)n3n2)C1,,CCCCO,,O=C([O-])O.[Na+],,test
US20070249670A1,COc1ccc(-c2cc(N)c(C(=O)O)s2)cc1.Cc1cc(C)c(N=C=O)c(C)c1>>COc1ccc(-c2cc(NC(=O)Nc3c(C)cc(C)cc3C)c(C(=O)O)s2)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20050137193A1,Cc1ccc(C(=O)c2cc(Cl)ccc2N)cn1.O=S(=O)(Cl)c1ccc(Br)c(F)c1>>Cc1ccc(C(=O)c2cc(Cl)ccc2NS(=O)(=O)c2ccc(Br)c(F)c2)cn1,,c1ccncc1,,,,test
US20090176793A1,Clc1ccc(N2CCN(C3CC3)CC2)nn1.OB(O)c1ccc2c(c1)OCO2>>c1cc2c(cc1-c1ccc(N3CCN(C4CC4)CC3)nn1)OCO2,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20110230485A1,NS(=O)(=O)c1ccc(Nc2ncnc(Cl)c2[N+](=O)[O-])cc1.OB(O)c1ccc(C(F)(F)F)cc1F>>NS(=O)(=O)c1ccc(Nc2ncnc(-c3ccc(C(F)(F)F)cc3F)c2[N+](=O)[O-])cc1,,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20100305133A1,CCCC[Sn](CCCC)(CCCC)c1cccs1.CCOC(=O)CNC(=O)c1c(O)c(Br)cc2nccnc12>>CCOC(=O)CNC(=O)c1c(O)c(-c2cccs2)cc2nccnc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US05106861,CC(C)(C)OC(=O)N[C@@H]1Cc2ccccc2[C@@H]2O[C@@H]21.C[Al](C)C>>C[C@@H]1c2ccccc2C[C@@H](NC(=O)OC(C)(C)C)[C@H]1O,,CCCCCC,,,,test
US20040054182A1,Cc1ccc2nc(C(F)(F)F)c(N)c(NCCC3CCN(C(=O)OC(C)(C)C)CC3)c2c1.O=C(Cl)c1ccc(I)cc1>>Cc1ccc2nc(C(F)(F)F)c3nc(-c4ccc(I)cc4)n(CCC4CCN(C(=O)OC(C)(C)C)CC4)c3c2c1,,Cc1ccccc1,,CCN(CC)CC,,test
US05998433,CN(C)Cc1cc2c(o1)CCN(C(=O)/C(=C/c1ccccc1)c1ccccc1)C2.Cl>>CN(C)Cc1cc2c(o1)CCN(C(=O)/C(=C/c1ccccc1)c1ccccc1)C2.Cl,,CCOC(C)=O,CO,,,test
US20130293094A1,Ic1cccc2c1oc1c([Si](c3ccccc3)(c3ccccc3)c3ccccc3)cccc12.OB(O)c1cccc(Cl)c1>>Clc1cccc(-c2cccc3c2oc2c([Si](c4ccccc4)(c4ccccc4)c4ccccc4)cccc23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[K+].[K+],,test
US04316839,CCOC(=O)c1ncn2c1CNC(=O)c1cc(F)ccc1-2.CI>>CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(F)ccc1-2,,CN(C)C=O,,O,[H-].[Na+],test
US04092304,CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Oc1cc(Cl)c(Cl)cc1Cl.CSCC[C@H](N)C(=O)OCc1ccccc1>>CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1,,ClCCl,,,,test
US20160002225A1,CCOC(=O)c1cccc(O)c1.COc1ccc(Cn2nc(I)c3c(Cl)ccnc32)cc1>>CCOC(=O)c1cccc(Oc2ccnc3c2c(I)nn3Cc2ccc(OC)cc2)c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US06423716B1,CC(C)(C)OC(=O)N1CCNCC1.O=C=Nc1ccc(Oc2ccccc2)cc1>>CC(C)(C)OC(=O)N1CCN(C(=O)Nc2ccc(Oc3ccccc3)cc2)CC1,,CO,,ClCCl,,test
US04348527,CC1CN(c2ccc(Cl)c(Cl)c2)N=C1NC=O.O=C(NC1=NN(c2ccc(Cl)c(Cl)c2)CC1)C(F)(F)F>>O=CNC1=NN(c2ccc(Cl)c(Cl)c2)CC1,,O=CO,,,,test
US05536721,CC(=O)c1c(Cl)n(Cc2ccccc2)c2ccccc12.COC(=O)CS>>COC(=O)c1sc2c(c1C)c1ccccc1n2Cc1ccccc1,,CCOC(C)=O,CO,O,O=C([O-])[O-].[K+].[K+],test
US20150057265A1,C1COCCN1.CCOC(=O)c1c(NCc2ccc(OC)cc2)sc2cc(Br)cnc12>>CCOC(=O)c1c(NCc2ccc(OC)cc2)sc2cc(N3CCOCC3)cnc12,,CCOC(C)=O,,Cc1ccccc1,O=C([O-])[O-].[Cs+].[Cs+],test
US20100331367A1,CCC(=O)N(c1ccc(Cl)c(Cl)c1)C1CCN(Cc2ccccc2)CC1>>CCC(=O)N(c1ccc(Cl)c(Cl)c1)C1CCNCC1,,ClCCCl,,CC(Cl)OC(=O)Cl,,test
US20130172353A1,COc1ccc(CN)c(OC)c1.Cc1ccc(F)c(NC(=O)Nc2ccc(-c3snc(Cl)c3C#N)cc2)c1>>COc1ccc(CNc2nsc(-c3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)c2C#N)c(OC)c1,,ClCCl,,,,test
US20030130238A1,C=C=CCOc1ccc(S(=O)(=O)NC(C(=O)OC)C(C)C)cc1.CI>>C=C=CCOc1ccc(S(=O)(=O)N(C)C(C(=O)OC)C(C)C)cc1,,C1CCOC1,,[H-].[Na+],,test
US04291034,CC(=O)C=Cc1ccc(Cl)c(Cl)c1.CCC(CC)(C(=O)[O-])C(=O)[O-]>>O=C1CC(=O)CC(c2ccc(Cl)c(Cl)c2)C1,,CCO,,[Na],,test
US20110230414A1,CC(C)(C)S(=O)/N=C/C1CC1.CC(C)C#N>>CC(C)(C#N)C(NS(=O)C(C)(C)C)C1CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20100160255A1,CCN1C(=O)C2(CCCN(C3CCN(C(=O)c4c(NC(=O)OC(C)(C)C)sc5ccccc45)CC3)C2)N=C1C>>CCN1C(=O)C2(CCCN(C3CCN(C(=O)c4c(N)sc5ccccc45)CC3)C2)N=C1C,,O=C(O)C(F)(F)F,,O=C([O-])O.[Na+],,test
US04994486,COc1ccc(C)c2c1C[C@@H](CN=[N+]=[N-])O[C@H]2CN=[N+]=[N-]>>COc1ccc(C)c2c1C[C@@H](CN)O[C@H]2CN,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120252853A1,C=C[Mg]Br.O=[N+]([O-])c1ccc(Br)cc1F>>Fc1cc(Br)cc2cc[nH]c12,,C1CCOC1,,[Cl-].[NH4+],,test
US20040097566A1,CC(C)(C)[Si](C)(C)Cl.Oc1c(F)cc(Br)cc1C12CC3CC(CC(C3)C1)C2>>CC(C)(C)[Si](C)(C)Oc1ccc(F)cc1Br,CN(C)c1ccncc1,CN(C)C=O,,CCN(CC)CC,O,test
US04220646,O=C(O)C(F)(F)F.O=C(OC1c2ccccc2C(=O)N1c1ccc2ccc(Cl)nc2n1)N1CCNCC1>>O=C(OC1c2ccccc2C(=O)N1c1ccc2ccc(Cl)nc2n1)N1CCN(C(=O)C(F)(F)F)CC1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20160272592A1,O=Cc1ccc(C(F)(F)F)c(F)c1>>OCc1ccc(C(F)(F)F)c(F)c1,,CO,,[BH4-].[Na+],,test
US20090042852A1,CCOC(=O)c1cc(C#N)c(N2CCNC(CCC(=O)OC(C)(C)C)C2)nc1C(F)(F)F.O=C=NS(=O)(=O)c1ccccc1>>CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)NS(=O)(=O)c3ccccc3)C(CCC(=O)OC(C)(C)C)C2)nc1C(F)(F)F,,ClCCl,,,,test
US05854277,CC(C)OB(OC(C)C)OC(C)C.CCOc1ccc(Br)cc1>>CCOc1ccc(B(O)O)cc1,,C1CCOC1,,[Mg],,test
US20150158878A1,COC(=O)c1nc(NC(=O)c2ccccc2OC(F)(F)F)n[nH]1>>O=C(O)c1nc(NC(=O)c2ccccc2OC(F)(F)F)n[nH]1,,O,,CCO,[K+].[OH-],test
US20030162787A1,COC(=O)c1ccc(NC(=O)[C@H]2C[C@@H](OC)CN2)cc1.O=C=Nc1ccc(Cl)cc1>>COC(=O)c1ccc(NC(=O)[C@H]2C[C@@H](OC)CN2C(=O)Nc2ccc(Cl)cc2)cc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20150361100A1,CC(c1cc2ccccn2c1-c1ccccn1)n1nc(I)c2c(N)ncnc21.CC1(C)OB(c2cncc(O)c2)OC1(C)C>>CC(c1cc2ccccn2c1-c1ccccn1)n1nc(-c2cncc(O)c2)c2c(N)ncnc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20150099883A1,CC(C)(N)c1ccccn1.O=C(NOc1cc2sc(C(F)(F)F)nc2cn1)Oc1ccccc1>>CC(C)(NC(=O)NOc1cc2sc(C(F)(F)F)nc2cn1)c1ccccn1,,C1CCOC1,,CCN(CC)CC,,test
US20020173653A1,CCCCOCCCN.O=[N+]([O-])c1cnc2cccnc2c1Cl>>CCCCOCCCNc1c([N+](=O)[O-])cnc2cccnc12,,ClCCl,,CCN(CC)CC,O,test
US04760075,CSC(=C[N+](=O)[O-])NCCSCc1csc(CN(C)C)n1.NC1CC1>>CN(C)Cc1nc(CSCCNC(=C[N+](=O)[O-])NC2CC2)cs1,,CCO,,,,test
US06300363B1,O=C(c1ccccn1)c1[nH]c2cc(Cl)ccc2c1[N+](=O)[O-]>>Nc1c(C(=O)c2ccccn2)[nH]c2cc(Cl)ccc12,[Fe],CCO,,[Cl-].[NH4+],,test
US03946019,CCOC(=O)CON=c1c2nccc3c(Cl)ccc(c32)n2cccc12>>O=C(O)CON=c1c2nccc3c(Cl)ccc(c32)n2cccc12,,CCO,,Cl,[Na+].[OH-],test
US05922724,CCB(CC)c1cccnc1.N#Cc1ccc2c(c1)ncn2-c1cccc(I)c1>>N#Cc1ccc2c(c1)ncn2-c1cccc(-c2cccnc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20090054681A1,C=C[Mg]Cl.O=Cc1cccc(Br)c1O>>C=CC(O)c1cccc(Br)c1O,,C1CCOC1,,[Cl-].[NH4+],,test
US20050192359A1,COc1ccc(-c2ccccc2NC(=O)C(O)c2ccc(C)cc2)cc1OC.CS(=O)(=O)Cl>>COc1ccc(-c2ccccc2NC(=O)C(OC)c2ccc(C)cc2)cc1OC,,C1CCOC1,,CCN(CC)CC,O,test
US20010056095A1,O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)ccc3s2)c(=O)c2ccccc12.OCCN(CCO)CCO>>O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)ccc3s2)c(=O)c2ccccc12.OCCN(CCO)CCO,,CC(C)=O,,,,test
US20070105876A1,COC(=O)CC1CCCC1.Cc1cccc(C)c1-n1ncc(C(N)=O)c1N>>Cc1cccc(C)c1-n1ncc2c(=O)[nH]c(CC3CCCC3)nc21,,CCO,,Cl,[H-].[Na+],test
US20020035266A1,COC(=O)/C(=C/C1CCCC1)c1ccc(-n2nnnc2C)c(S(C)(=O)=O)c1>>Cc1nnnn1-c1ccc(/C(=C\C2CCCC2)C(=O)O)cc1S(C)(=O)=O,,CCO,,[Na+].[OH-],,test
US20150038515A1,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1cc(C(F)(F)F)ccc1Cl>>Cc1ccc(S(=O)(=O)Nc2cc(C(F)(F)F)ccc2Cl)cc1,,c1ccncc1,,,,test
US20090076275A1,CO.O=C(O)c1cc([N+](=O)[O-])c(F)cc1Cl>>COc1cc(Cl)c(C(=O)O)cc1[N+](=O)[O-],,CN(C)C=O,,C[O-].[Na+],,test
US20020040043A1,N#Cc1ccc(CCOc2cc(O)cc(Cl)c2)cc1.O=S(=O)(Cl)c1ccc(F)cc1Cl>>N#Cc1ccc(CCOc2cc(Cl)cc(OS(=O)(=O)c3ccc(F)cc3Cl)c2)cc1,,c1ccncc1,,O,,test
US20150353499A1,CC(=O)Cl.COc1ccc(F)cc1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)CCc2ccccc21>>CN[C@@H](C)C(=O)N[C@H]1CCc2ccccc2N(Cc2cc(F)ccc2OC)C1=O.Cl,,CO,,,,test
US20100152188A1,N#Cc1ccc(NC(=O)OCc2cccs2)cc1.NO>>N/C(=N/O)c1ccc(NC(=O)OCc2cccs2)cc1,,CCO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20050277640A1,BrCCBr.Cc1cc(Oc2ccc(Nc3cc(-c4ccc(O)cc4)nc(N)n3)cc2)ccn1>>Cc1cc(Oc2ccc(Nc3cc(-c4ccc(OCCBr)cc4)nc(N)n3)cc2)ccn1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20080269196A1,CC(C)(C)OC(=O)NCc1ccc(-c2nccc(NCC3CC3)n2)cc1>>NCc1ccc(-c2nccc(NCC3CC3)n2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080004325A1,COC(=O)CN(c1csc(-c2ccccc2)c1)S(=O)(=O)NC(=O)OC(C)(C)C>>COC(=O)CN(c1csc(-c2ccccc2)c1)S(N)(=O)=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160235716A1,COc1cc(C=O)cnc1NC(=O)OC(C)(C)C.C[C@H](N)C1CC1>>COc1cc(CN[C@@H](C)C2CC2)cnc1NC(=O)OC(C)(C)C,,CO,,[BH4-].[Na+],,test
US20150266867A1,CC(C)(C)OC(=O)NCCN1CCN(C[C@@H]2[C@H](NC(=O)/C(=N\OC(C)(C)C(=O)OC(C)(C)C)c3csc(NC(=O)OC(C)(C)C)n3)C(=O)N2S(=O)(=O)O)C1=O>>CC(C)(O/N=C(\C(=O)N[C@@H]1C(=O)N(S(=O)(=O)O)[C@@H]1CN1CCN(CCN)C1=O)c1csc(N)n1)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040034034A1,CC(O)=S.COc1ccc(Cl)cc1CCl>>COc1ccc(Cl)cc1CSC(C)=O,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130196952A1,Cc1csc(C(C)O)n1.O=C1CCC(=O)N1Br>>Cc1nc(C(C)O)sc1Br,,CN(C)C=O,O,,,test
US20140045862A1,COc1ccc(CN(c2ccncn2)S(=O)(=O)c2c(F)cc(O[C@H]3CC(F)(F)C[C@@H]3c3ccnn3C)cc2F)c(OC)c1>>Cn1nccc1[C@H]1CC(F)(F)C[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20110009405A1,Nc1cccnc1.O=[N+]([O-])c1c(Cl)nc(Cl)nc1N1CCOCC1>>O=[N+]([O-])c1c(Nc2cccnc2)nc(Cl)nc1N1CCOCC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20100222398A1,COc1ccc(Cl)cc1CC#N.[N-]=[N+]=Nc1ccc(Cl)cc1Cl>>COc1ccc(Cl)cc1-c1nnn(-c2ccc(Cl)cc2Cl)c1N,,CCO,CCOC(C)=O,C[O-].[Na+],,test
US20050107364A1,CCCCC1(C)C(=O)C(C2=NS(=O)(=O)c3cc(N)ccc3N2)=C(O)c2ccccc21.CS(=O)(=O)Cl>>CCCCC1(C)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21,,CC(C)=O,,Cl,c1ccncc1,test
US20120225866A1,BrCCCOC1CCCCO1.c1cncc(CCNCc2ccncc2)c1>>c1cncc(CCN(CCCOC2CCCCO2)Cc2ccncc2)c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20130225554A1,CC(C)(C)OC(=O)NC(C(=O)NNC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)NC(C(=O)NNC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2O)c1ccccc1,[Pd],CO,,,,test
US20160115177A1,COC(=O)C1=C(N)CCS1.S=C=Nc1ccccc1>>O=c1c2c([nH]c(=S)n1-c1ccccc1)CCS2,,c1ccncc1,,,,test
US20110112151A1,Cn1ccnc1S.O=C(CBr)C1(c2ccc(Cl)cc2)CCCC1>>Cn1ccnc1SCC(=O)C1(c2ccc(Cl)cc2)CCCC1,,CC#N,,CCN(CC)CC,,test
US20130137672A1,Cc1cc(C)nc(N2CC[C@@H]3CN[C@@H]3C2)n1.O=C(O)c1cccc(F)c1-c1ncccn1>>Cc1cc(C)nc(N2CC[C@@H]3CN(C(=O)c4cccc(F)c4-c4ncccn4)[C@@H]3C2)n1,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20120129840A1,CCCI.COC(=O)Cc1c(C)nc(Cl)nc1-c1ccc(C)cc1>>CCCC(C(=O)OC)c1c(C)nc(Cl)nc1-c1ccc(C)cc1,,CN(C)C=O,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04447425,CC(=O)OC(C)=O.C[C@]12CC[C@H]3[C@@H](CC[C@H]4CC[C@@H](N5CCCCC5)C[C@@]43C)[C@@H]1C[C@H](N1CCCCC1)[C@@H]2O>>CC(=O)O[C@H]1[C@@H](N2CCCCC2)C[C@H]2[C@@H]3CC[C@H]4CC[C@@H](N5CCCCC5)C[C@]4(C)[C@H]3CC[C@@]21C,,c1ccncc1,,O=C([O-])[O-].[Na+].[Na+],,test
US06448266B1,CCOC(=O)CC(C[N+](=O)[O-])C1(C(=O)OCCC(C)C)CC(OCc2ccccc2)C1>>CC(C)CCOC(=O)C1(C2CNC(=O)C2)CC(OCc2ccccc2)C1,[Ni],CCO,,[H][H],,test
US20060036101A1,CCN(CC)C(=O)C(=O)c1c[nH]c2ccc(N)cc12.Cc1c(S(=O)(=O)Cl)sc2ccc(Cl)cc12>>CCN(CC)C(=O)C(=O)c1c[nH]c2ccc(NS(=O)(=O)c3sc4ccc(Cl)cc4c3C)cc12,,CN(C)C=O,,,,test
US20160184318A1,CI.Cc1nc(CN2CCN(C(=O)OC(C)(C)C)[C@H](CO)C2)co1>>COC[C@@H]1CN(Cc2coc(C)n2)CCN1C(=O)OC(C)(C)C,,CCOC(C)=O,,[H-].[Na+],,test
US20070225267A1,CC(C)(C)CO[C@H]1CN(C(=O)OC(C)(C)C)[C@@H]([C@@H](O)[C@H](Cc2cc(F)cc(F)c2)[N+](=O)[O-])CO1>>CC(C)(C)CO[C@H]1CN(C(=O)OC(C)(C)C)[C@@H]([C@@H](O)[C@@H](N)Cc2cc(F)cc(F)c2)CO1,Cl[Ni]Cl,CO,,O,[BH4-].[Na+],test
US20040116422A1,CC(=O)OC(C)=O.CCOc1cc2nc[nH]c(=O)c2cc1O>>CCOc1cc2nc[nH]c(=O)c2cc1OC(C)=O,,c1ccncc1,,,,test
US20160024142A1,COc1cncc(B(O)O)c1.C[C@]12CC[C@@H]3c4ccc(C(N)=O)cc4CC[C@H]3[C@@H]1CC=C2I>>COc1cncc(C2=CC[C@H]3[C@@H]4CCc5cc(C(N)=O)ccc5[C@H]4CC[C@]23C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20140315917A1,COC[C@H](C)N.O=C=NCCCl>>COC[C@H](C)NC(=O)NCCCl,,C1CCOC1,,,,test
US20050090533A1,CNC.Cc1cc(F)ccc1-c1cc(N2CCC(S(=O)(=O)O)CC2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1cc(F)ccc1-c1cc(N2CCC(S(=O)(=O)N(C)C)CC2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,CN(C)C=O,ClCCl,O,O=C(Cl)C(=O)Cl,,test
US20050014840A1,BrCc1ccccc1.CCCCOc1ccc(S(=O)(=O)NCCO)cc1>>CCCCOc1ccc(S(=O)(=O)N(CCO)Cc2ccccc2)cc1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20110178115A1,O=S(=O)(N[C@@H](CO)CCO)c1ccc(F)cc1>>O=S(=O)(c1ccc(F)cc1)N1C[C@H]1CCO,,C1CCOC1,,CCCCP(CCCC)CCCC,,test
US20100310512A1,COC(=O)NC(C(=O)N1CC2(CC2)CC1c1ncc(-c2ccc(-c3ccc4cc(-c5cnc(C6CC(C#N)CN6C(=O)OC(C)(C)C)[nH]5)ccc4c3)cc2)[nH]1)C(C)C.Cl.ClCCl>>COC(=O)NC(C(=O)N1CC2(CC2)CC1c1ncc(-c2ccc(-c3ccc4cc(-c5cnc(C6CC(C#N)CN6)[nH]5)ccc4c3)cc2)[nH]1)C(C)C.Cl.Cl.Cl,,ClCCl,,C1COCCO1,,test
US20060211720A1,CCOc1cc(/C=N/c2ccc(C#N)cc2)c(F)c(OC(C)C)c1.Clc1ccc2nc(Br)ccc2c1>>CCOc1cc(CN(c2ccc(C#N)cc2)c2ccc3cc(Cl)ccc3n2)c(F)c(OC(C)C)c1,,C1CCOC1,,[Li]CCCC,,test
US20160016960A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc(C(=O)NCC(=O)Cc3ccc(F)cc3)nn2c1C1CCC(C)(C)CC1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>Cc1nc2cc(-c3ncc(Cc4ccc(F)cc4)s3)nn2c(C2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(=O)O,,Cc1ccccc1,,,,test
US20120157436A1,CC(C)(C)OC(=O)NN.Cn1ccnc1C(=O)O>>Cn1ccnc1C(=O)NNC(=O)OC(C)(C)C,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20150252038A1,COC(=O)C1CCN(Cc2cc(Cl)cc(Cl)c2)C(=O)C1>>O=C1CC(CO)CCN1Cc1cc(Cl)cc(Cl)c1,,C1CCOC1,CO,[BH4-].[Na+],,test
US05138069,CCCSc1ncc(C(=O)OCC)n1Cc1ccc(OCc2ccccc2)cc1>>CCCSc1ncc(CO)n1Cc1ccc(OCc2ccccc2)cc1,,C1CCOC1,C1CCOC1,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04769373,CN1CCC(=O)CC1.CNC>>CN1CC=C(N(C)C)CC1,,CCOCC,,,,test
US20150087663A1,Nc1ccccc1.O=c1[nH]c2cccc(Cl)c2c(=O)o1>>Nc1cccc(Cl)c1C(=O)Nc1ccccc1,,C1COCCO1,,,,test
US20130158002A1,Cc1ccc(CN=[N+]=[N-])cc1-c1ccc2c(n1)N(C)S(=O)(=O)N2CC1CC1(F)F>>Cc1ccc(CN)cc1-c1ccc2c(n1)N(C)S(=O)(=O)N2CC1CC1(F)F,,C1CCOC1,CCOC(C)=O,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05686459,CC1C2C(=O)N(Cc3ccccc3)C(=O)C2C(c2ccc(Br)cc2)N1C.N#C[Cu]>>CC1C2C(=O)N(Cc3ccccc3)C(=O)C2C(c2ccc(C#N)cc2)N1C,,CN(C)C=O,,,,test
US20150045266A1,CCCCCCCCCCBr.CCCCn1ccnc1>>CCCCCCCCCCn1cc[n+](CCCC)c1.[Br-],,Cc1ccccc1,,,,test
US06211234B1,COC(=O)c1ccc(OCc2ccccc2)cc1O.Cc1ccccc1C(C)O>>COC(=O)c1ccc(OCc2ccccc2)cc1OC(C)c1ccccc1C,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090005380A1,CC(C)N1CCN(C(=O)[C@@H]2CC[C@@H](O)CC2)CC1.N#Cc1ccc(Cl)nc1>>CC(C)N1CCN(C(=O)[C@@H]2CC[C@@H](Oc3ccc(C#N)cn3)CC2)CC1,,CC(=O)N(C)C,,[H-].[Na+],,test
US04093736,CCC(=O)C(CCCCCCc1ccc(O)cc1)C(=O)CC.CCOCCBr>>CCOCCOc1ccc(CCCCCCC(C(=O)CC)C(=O)CC)cc1,,CC(C)=O,,[I-].[K+],,test
US06063789,CCO.Cl.NC1=NC(c2cccs2)Cc2ccsc21>>CCC1Cc2ccsc2C(N)=N1.Cl,[Pd],CCO,,[H][H],,test
US20080269219A1,COC(=O)CCc1oc(Cl)nc1-c1ccc(Cl)cc1.Sc1ncccn1>>COC(=O)CCc1oc(Sc2ncccn2)nc1-c1ccc(Cl)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130143862A1,C=C(OCC)c1ccc(N(CC2(c3ncccc3F)CCC2)C(=O)OC(C)(C)C)nn1>>CC(=O)c1ccc(N(CC2(c3ncccc3F)CCC2)C(=O)OC(C)(C)C)nn1,,CCO,,Cl,,test
US20040142958A1,CCOCC.C[Mg]I.N#Cc1ncccc1Cl>>CC(=O)c1ncccc1Cl,,C1CCOC1,,Cl,,test
US20030187020A1,CC(C)(C)OC(=O)NC(=O)OC(C)(C)C.Cc1ccc(CBr)cc1Br>>Cc1ccc(CN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc1Br,,C1CCOC1,,[H-].[Na+],,test
US20080096921A1,CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CCl.CCOC(=O)c1ccc2cc(-c3ccc(O)cc3)c(F)cc2n1>>CCOC(=O)c1ccc2cc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3)c(F)cc2n1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20030028022A1,CC(C)(C)OC(=O)n1c(CNC2CCCc3cccnc32)nc2ccccc21.COC(=O)c1ccc(C=O)cc1>>COC(=O)c1ccc(CN(Cc2nc3ccccc3[nH]2)C2CCCc3cccnc32)cc1,,ClCCl,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],,test
US20120309966A1,COc1cc(B2OC(C)(C)C(C)(C)O2)c(F)cc1N.COc1cccc2c1cc(C(=O)O)n2C>>COc1cc(B2OC(C)(C)C(C)(C)O2)c(F)cc1NC(=O)c1cc2c(OC)cccc2n1C,,ClCCl,c1ccncc1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20100087471A1,Cc1ccc(N(N)CCc2ccc(Cl)nc2)cc1.O=C1CCN2CCC1CC2>>Cc1ccc2c(c1)c1c(n2CCc2ccc(Cl)nc2)C2CCN(CC2)C1,,C1COCCO1,,O=S(=O)(O)O,[Na+].[OH-],test
US20060079533A1,CC(C)(C)OC(=O)N1CCC(c2ccc(OCCCOCc3ccccc3)cc2)C(OCc2ccc3cnccc3c2)C1.CI>>CN1CCc2cc(COC3CN(C(=O)OC(C)(C)C)CCC3c3ccc(OCCCOCc4ccccc4)cc3)ccc2C1,,CO,ClC(Cl)Cl,[BH4-].[Na+],,test
US20090298836A1,COC1=N[C@H](C(C)C)C(OC)=NC1.O=Cc1ccc(C(F)(F)F)cc1>>COC1=N[C@@H]([C@@H](O)c2ccc(C(F)(F)F)cc2)C(OC)=N[C@@H]1C(C)C,,C1CCOC1,CCOC(C)=O,[Li]CCCC,,test
US20070191344A1,O=[N+]([O-])c1cc(Nc2cc(Cl)ncn2)ccc1OCc1ccccc1>>Nc1cc(Nc2cc(Cl)ncn2)ccc1OCc1ccccc1,[Zn],CCO,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US20160176861A1,CCOC(=O)c1c(CO)noc1C1CC1.Cc1cccc(C)c1O>>CCOC(=O)c1c(COc2c(C)cccc2C)noc1C1CC1,,Cc1ccccc1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090221583A1,CC(=O)Oc1ccccc1C(=O)O.CCN=C=NCCCN(C)C.CN(C)C=O.On1nnc2ccccc21>>CCOC(=O)CNC(=O)c1ccccc1OC(C)=O,,O,,CCN(C(C)C)C(C)C,,test
US20020035272A1,COc1c(C(C)C)cc(C(=O)c2c(Cc3cccc(Br)c3)oc(C)c2C)cc1C(C)C>>Cc1oc(Cc2cccc(Br)c2)c(C(=O)c2cc(C(C)C)c(O)c(C(C)C)c2)c1C,,ClCCl,,BrB(Br)Br,,test
US20110053933A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC(Oc2ccc(F)cc2)CC1.Cl>>C[C@H](N)C(=O)N1CCC(Oc2ccc(F)cc2)CC1.Cl,,CCO,,,,test
US20130338066A1,BrCc1ccc(-c2ccccc2)cc1.O=S([O-])[O-].[Na+]>>O=S(=O)([O-])Cc1ccc(-c2ccccc2)cc1.[Na+],,CO,,O,,test
US20050197328A1,CC(C)(C)OC(=O)N1CCC(O)CC1.CCn1c(-c2nonc2N)nc2cncc(O)c21>>CCn1c(-c2nonc2N)nc2cncc(OC3CCN(C(=O)OC(C)(C)C)CC3)c21,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cccnc3F)n2)cc1.COc1ccc(COc2cc(N)ccn2)cc1>>COc1ccc(COc2cc(Nc3ncccc3-c3nc(C)nc(N(Cc4ccc(OC)cc4)Cc4ccc(OC)cc4)n3)ccn2)cc1,,C1CCOC1,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20090163714A1,[N-]=[N+]=NCC(=O)c1cccc(OC(F)(F)F)c1>>NCC(=O)c1cccc(OC(F)(F)F)c1,[Pd],CCO,,,,test
US20140088094A1,CS(=O)(=O)OS(C)(=O)=O.O=C(Nc1ccc2c(c1)N(S(=O)(=O)c1ccc(F)cc1)C[C@H](CO)O2)c1c(F)cccc1Cl>>CS(=O)(=O)OC[C@H]1CN(S(=O)(=O)c2ccc(F)cc2)c2cc(NC(=O)c3c(F)cccc3Cl)ccc2O1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070027139A1,CC(C)(C)OC(=O)N1CCN(c2cccc3cc(Oc4ccccc4)cnc23)CC1.Cl>>Cl.c1ccc(Oc2cnc3c(N4CCNCC4)cccc3c2)cc1,,C1COCCO1,,,,test
US05552397,CI.O=C(O)[C@H](CCCCO)N1C(=O)c2ccccc2C1=O>>COC(=O)[C@H](CCCCO)N1C(=O)c2ccccc2C1=O,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050080258A1,NC(CO)c1ccccc1.O=C(Cl)CCl>>O=C1COC[C@@H](c2ccccc2)N1,,C1CCOC1,,CCN(CC)CC,,test
US20130090404A1,O=C(O)c1ccc(S(=O)(=O)O)cc1C(=O)O.[OH-]>>O=C(O)c1ccc(O)cc1C(=O)O,,O,,Cl,,test
US20100249149A1,CC(=O)OC(C)=O.COc1ccccc1-c1cc(NC(=O)C2CCCNC2)ncn1>>COc1ccccc1-c1cc(NC(=O)C2CCCN(C(C)=O)C2)ncn1,,ClCCl,,,,test
US20020028835A1,CCCCN(C(=O)CC(=O)OCC)c1ccc(N2CCC(NC[C@H](O)c3ccc(O)c(NS(C)(=O)=O)c3)CC2)cc1>>CCCCN(C(=O)CC(=O)O)c1ccc(N2CCC(NC[C@H](O)c3ccc(O)c(NS(C)(=O)=O)c3)CC2)cc1,,CCO,O,CC(=O)O,[Na+].[OH-],test
US20100143341A1,CC(Br)Br.Cc1csc2ncnc(Nc3ccccc3O)c12>>Cc1csc2ncnc(Nc3ccccc3OCCBr)c12,,CC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040209921A1,CC(C)(C)OC(=O)NCCCCN.ClCc1nc2ccccc2[nH]1>>CC(C)(C)OC(=O)NCCCCNCc1nc2ccccc2[nH]1,,CC#N,,CCN(C(C)C)C(C)C,,test
US05369084,CC(C)N(C(=O)c1ccncc1)C(C)C.CC1(C)C(=O)c2cccc3cccc1c23>>CC(C)N(C(=O)c1ccncc1C1(O)c2cccc3cccc(c23)C1(C)C)C(C)C,,C1CCOC1,O,CC(C)NC(C)C,[Li]CCCC,test
US06121316,CC(C)[Si](Cl)(C(C)C)C(C)C.CCOC(=O)C[C@@H](C)O>>CCOC(=O)C[C@@H](C)O[Si](C(C)C)(C(C)C)C(C)C,,CN(C)C=O,,O,c1c[nH]cn1,test
US20080146565A1,CCCCSc1nccc(Cl)n1.NS(=O)(=O)c1c[nH]c2ccccc12>>CCCCSc1nccc(-n2cc(S(N)(=O)=O)c3ccccc32)n1,,CN(C)C=O,,[H-].[Na+],,test
US05998433,CN(C)Cc1cc2c(o1)CN(C(=O)c1ccc(C(=O)c3ccccc3)cc1)CCC2.Cl>>CN(C)Cc1cc2c(o1)CN(C(=O)c1ccc(C(=O)c3ccccc3)cc1)CCC2.Cl,,CO,,,,test
US20100286115A1,CCCCc1noc(CO)c1COc1cc(C(=O)OC)n(C)n1>>CCCCc1noc(CO)c1COc1cc(C(=O)O)n(C)n1,,C1COCCO1,O,[Na+].[OH-],,test
US03972894,CCO.CCOC(=O)c1cc(C)c2c(c1)C(C)C(=S)N2>>CCOC(=O)c1cc(C)c2c(c1)CC(=O)N2,[Ni],,,,,test
US05798344,CCOP(=O)(Cc1ccc(-c2nc3cc(N)ccc3c(=O)n2C)cc1)OCC.O=S(=O)(Cl)c1ccccc1>>CCOP(=O)(Cc1ccc(-c2nc3cc(NS(=O)(=O)c4ccccc4)ccc3c(=O)n2C)cc1)OCC,,c1ccncc1,,O=C([O-])O.[Na+],,test
US20150011753A1,CC(=O)Oc1coc2ccccc12>>O=C1COc2ccccc21,,CO,,O=S(=O)(O)O,,test
US20070276030A1,Cc1ccc(Br)cc1SCC(=O)O.O=S(Cl)Cl>>Cc1ccc(Br)cc1SCC(=O)Cl,CN(C)C=O,ClCCCl,,,,test
US03948917,CN1CCN(C(=O)Cl)CC1.COc1ccc(N2C(=O)C3=C(SCCS3)C2O)nn1>>COc1ccc(N2C(=O)C3=C(SCCS3)C2OC(=O)N2CCN(C)CC2)nn1,,C1CCOC1,,CCO,[H-].[Na+],test
US05703249,CC1(C)OC2COC(CBr)OCC2O1>>C=C1OCC2OC(C)(C)OC2CO1,,C1CCOC1,O,,,test
US20120028918A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Nc1ncc(Br)cc1CO>>Nc1ncc(B(O)O)cc1CO,,C1COCCO1,,O,CC(=O)[O-].[K+],test
US20060135447A1,CC(=O)c1ccnc2ncccc12.C[Si](C)(C)OS(=O)(=O)C(F)(F)F>>C=C(O[Si](C)(C)C)c1ccnc2ncccc12,,ClCCl,,Cc1cccc(C)n1,,test
US04544667,CNC.NS(=O)(=O)c1cc2cc(CBr)ccc2o1>>CN(C)Cc1ccc2oc(S(N)(=O)=O)cc2c1,,CO,,,,test
US20110183954A1,COC[C@H](Nc1nc(Cl)nc(Nc2cn(C)cn2)n1)c1ncc(F)cc1F.C[C@H]1CNC[C@@H](C)O1>>COC[C@H](Nc1nc(Nc2cn(C)cn2)nc(N2C[C@H](C)O[C@H](C)C2)n1)c1ncc(F)cc1F,,CCO,,CCN(C(C)C)C(C)C,,test
US06143779,O=C(Cl)c1ccccc1.O=C1C(=Cc2ccc3c(c2)OCO3)Oc2cc(O)ccc21>>O=C(Oc1ccc2c(c1)OC(=Cc1ccc3c(c1)OCO3)C2=O)c1ccccc1,,c1ccncc1,,CCOC(C)=O,,test
US20050038056A1,COc1cccc(-c2c(C)n(Cc3c(F)cccc3S(C)(=O)=O)c(=O)n(C[C@H](NC(=O)OC(C)(C)C)c3ccccc3)c2=O)c1F>>COc1cccc(-c2c(C)n(Cc3c(F)cccc3S(C)(=O)=O)c(=O)n(C[C@H](N)c3ccccc3)c2=O)c1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140206681A1,COc1cc(C(=O)O)c(F)cc1Br.Nc1cc(C(F)(F)F)ccn1>>COc1cc(C(=O)Nc2cc(C(F)(F)F)ccn2)c(F)cc1Br,CN(C)c1ccncc1,ClCCl,,CN(C)C=O,O=S(Cl)Cl,test
US20070124152A1,COC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(-c2ccc(C(=O)N(C)C)cc2)c1=O.NCCCN1CCCC1=O>>CN(C)C(=O)c1ccc(-n2c(=O)c(C(=O)NCCCN3CCCC3=O)c(O)c3ncc(Cc4ccc(F)cc4)cc32)cc1,,CO,,,,test
US20110034436A1,CCOC(=O)CC1(NC(=O)c2ccccc2)CCC1>>OCCC1(NCc2ccccc2)CCC1,O,C1CCOC1,CCOC(C)=O,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040019037A1,COP(=O)(CC(=O)CCCCCNC(=O)OC(C)(C)C)OC.Cc1ncc(C=O)cn1>>Cc1ncc(C=CC(=O)CCCCCNC(=O)OC(C)(C)C)cn1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US04064257,C#CCCCCNC(=O)c1cnc(OCC(O)CO)s1.CS(=O)(=O)Cl>>C#CCCCCNC(=O)c1cnc(OCC(O)COS(C)(=O)=O)s1,,c1ccncc1,,,,test
US20090209607A1,CCCc1sc(C(=O)OC)cc1-c1c(C)cnn1C>>CCCc1sc(C(=O)O)cc1-c1c(C)cnn1C,,C1CCOC1,,[Na+].[OH-],,test
US05278181,COC(=O)Nc1nc2cc(C(=O)c3ccc(F)cc3)ccc2[nH]1.NO>>COC(=O)Nc1nc2cc(C(=NO)c3ccc(F)cc3)ccc2[nH]1,,CO,O,Cl,[NH4+].[OH-],test
US20120245170A1,N#Cc1ccc(-c2c(C#N)c(-c3ccc(O)cc3F)nc3[nH]ncc23)cc1.O>>N#Cc1c(-c2ccc(O)cc2F)nc2[nH]ncc2c1-c1ccc(C(N)=O)cc1,,CC(C)(C)O,O,Cl,[K+].[OH-],test
US04353827,CCOC(=O)c1ncn2c1[C@@H]1CCCN1C(=O)c1c(Cl)cccc1-2>>O=C(O)c1ncn2c1[C@@H]1CCCN1C(=O)c1c(Cl)cccc1-2,,O,,CCO,[Na+].[OH-],test
US04857539,COc1ccc(-c2nc(C)c(C)s2)cc1>>Cc1nc(-c2ccc(O)cc2)sc1C,,c1ccncc1,,Cl,[NH4+].[OH-],test
US20100168082A1,Cc1cc2c(F)c(Oc3cc(CS(C)(=O)=O)ncn3)ccc2[nH]1.O=C=Nc1cccc(C(F)(F)F)c1>>Cc1cc2c(F)c(Oc3cc(CS(C)(=O)=O)ncn3)ccc2n1C(=O)Nc1cccc(C(F)(F)F)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20150218129A1,O=C(C=Cc1ccc(OC2CCNCC2)cc1)N1CCOCC1.O=C1CCC1>>O=C(C=Cc1ccc(OC2CCN(C3CCC3)CC2)cc1)N1CCOCC1,,CC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US06462183B1,CC(=O)OC[C@H]1O[C@H](O[C@@H]2[C@@H](COC(C)=O)O[C@@H](N=[N+]=[N-])[C@H](OC(C)=O)[C@H]2OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O>>CC(=O)OC[C@H]1O[C@H](O[C@@H]2[C@@H](COC(C)=O)O[C@@H](N)[C@H](OC(C)=O)[C@H]2OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O,[Pd],CO,,,,test
US06169095A,CCON(C(=O)C(C=C=O)N1C(=O)c2ccccc2C1=O)c1ccc(Cl)c(COc2cccc3ccc(C)nc23)c1Cl>>Cc1ccc2cccc(OCc3c(Cl)ccc(N4CC(=O)NCC4=O)c3Cl)c2n1,,CO,ClCCl,CN,,test
US20100056573A1,NC1CCNC1.O=Cc1ccccc1>>C(=NC1CCNC1)c1ccccc1,,Cc1ccccc1,,,,test
US20100010035A1,COc1nc(C)cnc1N(C(=O)NOCC(C)C)S(=O)(=O)c1sccc1-c1ccc(C=O)cc1>>COc1nc(C)cnc1N(C(=O)NOCC(C)C)S(=O)(=O)c1sccc1-c1ccc(CO)cc1,,C1CCOC1,,[Na+].[OH-],,test
US20130053370A1,Cc1csc2c(Cl)ncnc12.O=C1CCC(=O)N1Br>>Clc1ncnc2c(CBr)csc12,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20120116118A1,BrBr.Cc1cccc(C)c1CC(=O)O>>Cc1ccc(Br)c(C)c1CC(=O)O,,C1CCCCC1,,CC(=O)O,,test
US20060128734A1,COc1cc(Oc2ccc([N+](=O)[O-])cc2)ccn1>>COc1cc(Oc2ccc(N)cc2)ccn1,[Ni],CCOC(C)=O,,,,test
US20160137636A1,COc1ccc(Br)c(C#N)c1.OB(O)c1cc(F)cc(F)c1>>COc1ccc(-c2cc(F)cc(F)c2)c(C#N)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US09248117B2,C=CC1CO1.CC1(CS)COC(=O)N1>>C=CC(O)CSCC1(C)COC(=O)N1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030236296A1,CCOC1OC(=O)CC1NC(=O)C1CCC2CC=CCC(NC(=O)c3nccc4ccccc34)C(=O)N21>>O=C1CC(NC(=O)[C@@H]2CC[C@H]3CC=CC[C@H](NC(=O)c4nccc5ccccc45)C(=O)N32)C(O)O1,,O,,O=C(O)C(F)(F)F,,test
US20130252941A1,O=P(Br)(Br)Br.[O-][n+]1cc(Br)c2nn(-c3c(Cl)cccc3Cl)cc2c1>>Clc1cccc(Cl)c1-n1cc2c(Br)ncc(Br)c2n1,,ClCCCl,,,,test
US20060058315A1,CC(C(=O)c1ccccc1)S(=O)(=O)N(C)C.CI>>CN(C)S(=O)(=O)C(C)(C)C(=O)c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US07232805B2,COc1ccc(C(NCCCC[C@H](N)C(=O)O)(c2ccccc2)c2ccccc2)cc1.O=C(N[C@@H](Cc1ccccc1)C(=O)ON1C(=O)CCC1=O)OCC1c2ccccc2-c2ccccc21>>COc1ccc(C(NCCCC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)(c2ccccc2)c2ccccc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20050043351A1,O=C(Nc1cccc2[nH]ncc12)NC1CCc2c1cccc2N1CCCCC1>>O=C(Nc1cccc2[nH]ncc12)N[C@H]1CCc2c1cccc2N1CCCCC1,,CO,,Cl,,test
US20070208018A1,CN.COC(=O)c1cc(F)c(C(F)(F)F)cc1[N+](=O)[O-]>>CNc1cc(C(=O)OC)c([N+](=O)[O-])cc1C(F)(F)F,,C1COCCO1,,,,test
US04254108,CCOC(=O)CN1C(=O)c2cccc3cccc(c23)C1=S>>O=C(O)CN1C(=O)c2cccc3cccc(c23)C1=S,,CO,,[Na+].[OH-],,test
US05998459,Cc1c(-c2ccccc2F)[nH]c(N)c1C#N.O=Cc1ccccc1>>Cc1c(-c2ccccc2F)[nH]c(NCc2ccccc2)c1C#N,,ClCCl,,O=S(=O)([O-])[O-].[Mg+2],,test
US05457225,CC(C)(C)c1cccc(C=O)c1O.CC[C@@H](N)CO>>CC[C@H](CO)N=Cc1cccc(C(C)(C)C)c1O,,CO,,,,test
US20140371201A1,CCI.O=c1ccc2cc(SCc3ccccc3)ccc2n1-c1cc(F)c(-c2cccc(F)c2)cc1O>>CCOc1cc(-c2cccc(F)c2)c(F)cc1-n1c(=O)ccc2cc(SCc3ccccc3)ccc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20030092740A1,COC(=O)c1sc(Br)nc1-c1ccc(OC)cc1>>COc1ccc(-c2nc(Br)sc2C(=O)O)cc1,,CO,O,[Li+].[OH-],,test
US04021441,ClCc1nnc2n1-c1ccccc1C(c1ccccc1Cl)=NC2.NC1CC1>>Clc1ccccc1C1=NCc2nnc(CNC3CC3)n2-c2ccccc21,,C1CCOC1,,[I-].[K+],,test
US06358992B1,CCc1c[nH]c2cc(C(=O)OC)ccc12.O=S(=O)(Cl)Cl>>CCc1c(Cl)[nH]c2cc(C(=O)OC)ccc12,,ClCCl,,,,test
US20040014962A1,CC(C)(C)[Si](OC1CN(c2nc(C#N)cs2)C1)(c1ccccc1)c1ccccc1>>N#Cc1csc(N2CC(O)C2)n1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100222299A1,COc1ccc(CC(C)[N+](=O)[O-])cc1OCc1ccccc1>>COc1ccc(CC(C)N)cc1OCc1ccccc1,[Ni],CO,,NN,O,test
US04567191,CCOC(=O)C(=O)c1ccccc1.NS(N)(=O)=O>>O=S1(=O)N=C(O)C(c2ccccc2)=N1,,CCO,,[Na],,test
US20150274740A1,CCOC(=O)CC(=O)c1ccc2[nH]nnc2c1.Nc1nc(-c2cccc(Cl)c2)n[nH]1>>O=c1cc(-c2ccc3[nH]nnc3c2)[nH]c2nc(-c3cccc(Cl)c3)nn12,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090036492A1,CC#CCOc1c(C)c(C)c(C=O)c(C)c1C.COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>CC#CCOc1c(C)c(C)c(CNC(=O)c2c(OC)cc(O)c3c2OC2=CC(O)=C(C(C)=O)C(=O)[C@]23C)c(C)c1C,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20050107449A1,CC(C)c1nc(-c2ccc(C(F)(F)F)cc2)sc1C(C)CO.COC(=O)CCc1ccc(O)cc1C>>COC(=O)CCc1ccc(OCC(C)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C(C)C)cc1C,,Cc1ccccc1,,CCCCP(CCCC)CCCC,,test
US04174210,CC(=O)C(C)O.Cc1cccc(C)c1N>>CC(=O)C(C)Nc1c(C)cccc1C,,c1ccccc1,,,,test
US04442115,CCOC(=O)c1nnn[nH]1.ClCc1ccccc1>>CCOC(=O)c1nnnn1Cc1ccccc1,,O=S1(=O)CCCC1,,[H-].[Na+],,test
US04153607,CCOC(=S)c1ccccc1.N#CCCl.N#CN>>N#Cc1sc(-c2ccccc2)nc1N,,CCO,,[Na],,test
US04326997,CC(C)CCC1CC(C)C(=O)C(C)C1.CI>>CC(C)CCC1CC(C)C(C)(O)C(C)C1,,CCOCC,,[Mg],,test
US20100130446A1,CS(C)(=O)=O.O=Cc1ccc(-c2ccc(C(CC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)[nH]2)nc1>>CS(=O)(=O)CC(O)c1ccc(-c2ccc(C(CC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)[nH]2)nc1,,C1CCOC1,,O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20120225110A1,C=C(C)C(=O)OCCOC(=O)CC(C)=O.C=CC(=O)NCCO.C=CC(=O)OCC(CC)CCCC>>C=C(C)C(=O)OCCOC(=O)CC(C)=O.C=CC(=O)NCCO.C=CC(=O)OCC(CC)CCCC,,CCOC(C)=O,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US04259486,C1COCCN1.CC(C)C=O>>CC(C)=CN1CCOCC1,,O,,,,test
US20080146569A1,COC(=O)c1ccc(Cl)nc1.N#Cc1ccccc1B(O)O>>COC(=O)c1ccc(-c2ccccc2C#N)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20050090669A1,COC(=O)c1cc(Oc2ccc3c(c2)C[C@@H](N(C[C@H](O)c2cccc(Cl)c2)C(=O)OC(C)(C)C)CC3)ccc1O[Si](C)(C)C(C)(C)C>>COC(=O)c1cc(Oc2ccc3c(c2)C[C@@H](N(C[C@H](O)c2cccc(Cl)c2)C(=O)OC(C)(C)C)CC3)ccc1O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05532236,CCOC(=O)NNc1nc2cc(-n3ccnc3C)c(C(F)(F)F)cc2n(OCc2ccccc2)c1=O>>CCOC(=O)NNc1nc2cc(-n3ccnc3C)c(C(F)(F)F)cc2n(O)c1=O,[Pd],CCO,CN(C)C=O,,,test
US20140357625A1,COC(=O)C(C)C1=NCCc2c(I)cccc21>>COC(=O)C(C)C1NCCc2c(I)cccc21,,CC(=O)O,,[Na+].[OH-],,test
US20090192195A1,CO.COC(OC)OC.O=Cc1ccc(SC2CCCCC2)cc1>>COC(OC)c1ccc(SC2CCCCC2)cc1,Cc1ccc(S(=O)(=O)O)cc1,CO,,C[O-].[Na+],,test
US07780952B2,CC(C)(C)OC(=O)NCCCCN(CCCNCc1ccc([N+](=O)[O-])cc1)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCCCN(CCCNCc1ccc(N)cc1)C(=O)OC(C)(C)C,,CCO,,NN,O,test
US20030176482A1,O=C(CBr)c1cc(Cl)ccc1O.c1c[nH]cn1>>O=C(Cn1ccnc1)c1cc(Cl)ccc1O,,CN(C)C=O,,,,test
US05064832,CSc1nc(O)cc(-c2cccc(C#N)c2)n1>>N#Cc1cccc(-c2cc(O)ncn2)c1,[Ni],,,,,test
US04863949,CC(CC(=O)NCCN)O[N+](=O)[O-].N#Cc1c[nH]c2cccc(OCC3CO3)c12.O=C(O)/C=C/C(=O)O>>CC(CC(=O)NCCNCC(O)COc1cccc2[nH]cc(C#N)c12)O[N+](=O)[O-].O=C(O)/C=C/C(=O)O,,CO,,CCCCO,,test
US20050131014A1,O=C(O)Cc1ccc(CBr)cc1.OCc1cnc2c(C(F)(F)F)cccc2c1-c1cccc(O)c1>>O=C(O)Cc1ccc(COc2cccc(-c3c(CO)cnc4c(C(F)(F)F)cccc34)c2)cc1,,CCOC(C)=O,ClCCl,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20140113944A1,CC(C)(C)OC(=O)N[C@@]1(C(=O)OC(C)(C)C)C[C@H](Sc2nc[nH]n2)[C@@H]2[C@H]1[C@H]2C(=O)OC(C)(C)C>>N[C@@]1(C(=O)O)C[C@H](Sc2nc[nH]n2)[C@@H]2[C@H]1[C@H]2C(=O)O,,C1COCCO1,,Cl,,test
US20070179118A1,CC(C)(C)OC(=O)N1CCN(c2ccc(N)nc2)CC1.CS(=O)c1ncc2cc(F)c(=O)n(C3CCCC3)c2n1>>CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3ncc4cc(F)c(=O)n(C5CCCC5)c4n3)nc2)CC1,,Cc1ccccc1,,,,test
US20150329570A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.C[C@H](O[Si](C)(C)C(C)(C)C)[C@@]1(NC(=O)N(C)C)C(=O)[C@]2(CO)O[C@@H]2[C@@H]1NC(=O)OCc1ccccc1>>C[C@H](O[Si](C)(C)C(C)(C)C)[C@@]1(NC(=O)N(C)C)C(=O)[C@]2(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)O[C@@H]2[C@@H]1NC(=O)OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,[Cl-].[NH4+],test
US20100179126A1,Cc1ncc(C#CCN(C)C)cc1[N+](=O)[O-]>>Cc1ncc(CCCN(C)C)cc1N,[Ni],CCO,CCO,,,test
US20100016371A1,CCCc1cn(-c2nc(C(=O)OCC)cs2)c2cc(Cl)ccc12>>CCCc1cn(-c2nc(C(=O)O)cs2)c2cc(Cl)ccc12,,CCO,,[Na+].[OH-],,test
US03961055,CCCCCCCOc1ccc2c(c1)N(CCCCl)c1cccc(S(=O)(=O)N(C)C)c1S2.OCCC1CCNCC1>>CCCCCCCOc1ccc2c(c1)N(CCCN1CCC(CCO)CC1)c1cccc(S(=O)(=O)N(C)C)c1S2,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US04179505,CCCCN=C=O.Cn1c(N)nc2cc(CN3CCN(C(c4ccccc4)c4ccccc4)CC3)ccc21>>CCCCNC(=O)Nc1nc2cc(CN3CCN(C(c4ccccc4)c4ccccc4)CC3)ccc2n1C,,C1CCOC1,,,,test
US20110112122A1,Cn1c2c(c3c(C(=O)OC(C)(C)C)c(S(=O)(=O)c4cccc([N+](=O)[O-])c4)ccc31)C1CCC(C2)N1>>Cn1c2c(c3c(C(=O)OC(C)(C)C)c(S(=O)(=O)c4cccc(N)c4)ccc31)C1CCC(C2)N1,[Fe],CCO,O,[Cl-].[NH4+],,test
US05442063,CNC(=O)C(=O)c1ccccc1COc1cc(C)ccc1C.NO>>CNC(=O)/C(=N/O)c1ccccc1COc1cc(C)ccc1C,,CO,,O=S(=O)(O)O,,test
US05041448,CC=CBr.Fc1ccc(Cn2c(NC3CCNCC3)nc3cncnc32)cc1>>C=CCN1CCC(Nc2nc3cncnc3n2Cc2ccc(F)cc2)CC1,,CCO,,O=C([O-])O.[Na+],,test
US20070093501A1,COC(=O)C(OC(=O)Nc1ccc(Cl)cc1)c1ccccc1>>O=C(Nc1ccc(Cl)cc1)OC(C(=O)O)c1ccccc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20040097566A1,CN(C)C=CC(=O)c1ccc(Br)cc1.N=C(N)C12CC3CC(CC(C3)C1)C2>>Brc1ccc(-c2ccnc(C34CC5CC(CC(C5)C3)C4)n2)cc1,,CCO,CCOC(C)=O,C,C[O-].[Na+],test
US20080171772A1,CC(=O)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(OC(C)C)cc2n1Cc1ccccn1.NO>>C/C(=N\O)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(OC(C)C)cc2n1Cc1ccccn1,,CO,,Cl,c1ccncc1,test
US20120289474A1,CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3cc(-c4ccccc4)sc3c2=O)CC1.CCc1coc(CCl)n1>>CCc1coc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(-c4ccccc4)cc32)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050143379A1,CC(C)(C)OC(=O)NCC(O)c1ccccc1.Sc1cc(Cl)ccc1Cl>>CC(C)(C)OC(=O)NCC(Sc1cc(Cl)ccc1Cl)c1ccccc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080269280A1,COCCNCC(=O)N1CC(=O)N(c2cccc(Cl)c2C)C1.O=S(=O)(Cl)c1cccc(Cl)c1>>COCCN(CC(=O)N1CC(=O)N(c2cccc(Cl)c2C)C1)S(=O)(=O)c1cccc(Cl)c1,,C1CCOC1,CCOC(C)=O,,,test
US20070135457A1,CC1(c2ccc(CCC#N)cc2)OCCO1>>CC1(c2ccc(CCCN)cc2)OCCO1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070208014A1,CC#N.O=C(c1nc2cc(Cl)c(Cl)cc2[nH]1)C(F)(F)F>>N#CCC(O)(c1nc2cc(Cl)c(Cl)cc2[nH]1)C(F)(F)F,,C1CCOC1,,[Li]CCCC,,test
US20090281079A1,C[Zn]C.Nc1ncnn2cc(Br)cc12>>Cc1cc2c(N)ncnn2c1,,C1COCCO1,,,,test
US20080064715A1,C[Mg]Br.O=Cc1cc2cc(N(Cc3ccccc3)Cc3ccccc3)ncc2[nH]1>>CC(O)c1cc2cc(N(Cc3ccccc3)Cc3ccccc3)ncc2[nH]1,,C1CCOC1,,CCOCC,[Cl-].[NH4+],test
US20100144655A1,C#C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1ccc2c(N)ncnc21.CC(C)C(=O)OC(=O)C(C)C>>C#C[C@@]1(O)[C@H](OC(=O)C(C)C)[C@@H](CO)O[C@H]1n1ccc2c(N)ncnc21,,CN(C)C=O,,CCN(CC)CC,,test
US20120252779A1,CC(C)(C)OC(=O)N1CCN(c2cc(F)c(F)c(C(=O)O)c2F)CC1>>CC(C)(C)OC(=O)N1CCN(c2cc(F)c(F)c(CO)c2F)CC1,,C1CCOC1,,B,,test
US20070010537A1,CC(C)(C)[Si](C)(C)OC1COc2ccccc2N(S(=O)(=O)c2cccc([N+](=O)[O-])c2)C1>>O=[N+]([O-])c1cccc(S(=O)(=O)N2CC(O)COc3ccccc32)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04012413,N#CCC(=O)NN.S=C1CN=C(c2ccccc2)c2cc(Cl)ccc2N1>>N#CCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2,,CCCCO,,,,test
US20080319080A1,C#CCOc1c(OC)cc(C(=O)O)cc1OC.O=S(Cl)Cl>>C#CCOc1c(OC)cc(C(=O)Cl)cc1OC,CN(C)C=O,Cc1ccccc1,,,,test
US20150011591A1,CC(C)COc1cccc(O)c1.CCOC(=O)CBr>>CCOC(=O)COc1cccc(OCC(C)C)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130336921A1,COC(=O)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2C(=O)Nc2ccn(-c3cccc(C(F)(F)F)c3)n2)c1>>O=C(O)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2C(=O)Nc2ccn(-c3cccc(C(F)(F)F)c3)n2)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20160024053A1,CC(=O)c1c[nH]c2cc(C(=O)N3CCOCC3)ccc12>>CCc1c[nH]c2cc(C(=O)N3CCOCC3)ccc12,[Pd],CCO,,CC(=O)O,,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4c(F)cccc4F)nc(Cl)c3n2)cc1.Nc1ccc(N2CCOCC2)cc1>>Fc1cccc(F)c1-c1nc(Nc2ccc(N3CCOCC3)cc2)c2[nH]ncc2n1,C1COCCO1,CO,,Cl,,test
US20050267093A1,C#CC(=O)Nc1ccc(-c2ccc(Cl)cc2)cc1.CC1(O)CCN(Cc2ccc(I)cc2)CC1>>CC1(O)CCN(Cc2ccc(C#CC(=O)Nc3ccc(-c4ccc(Cl)cc4)cc3)cc2)CC1,,CO,ClCCl,,,test
US20090186976A1,CCCCCCCC/C=C\CCCCCCCC(=O)OCC>>CCCCCCCC/C=C\CCCCCCCC(=O)OC,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,,,,,test
US05294734,C=C(C=O)CCCCCCNC(=O)OCc1ccccc1.[C-]#[N+]CC(=O)OCC>>C=C(CCCCCCNC(=O)OCc1ccccc1)C1OC=NC1C(=O)OCC,O=[Cu-],Cc1ccccc1,,,,test
US20040102360A1,CCOC(=O)c1cc2cc(Cl)ccc2n1S(=O)(=O)c1ccccc1.O=S(=O)(O)O>>CCOC(=O)c1c(S(=O)(=O)O)c2cc(Cl)ccc2n1S(=O)(=O)c1ccccc1,,ClCCl,,CC(=O)OC(C)=O,,test
US20100222321A1,O=P(Cl)(Cl)Cl.O=c1[nH]ccc2nc(-c3ccc(CN4CCC(c5n[nH]c(-c6ccccn6)n5)CC4)cc3)c(-c3ccccc3)cc12>>Clc1nccc2nc(-c3ccc(CN4CCC(c5nnc(-c6ccccn6)[nH]5)CC4)cc3)c(-c3ccccc3)cc12,,O,,CN(C)C=O,O=C([O-])O.[Na+],test
US20030195176A1,CC(C)(O)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C.CCC(CC)(C/C=C\Br)O[Si](CC)(CC)CC>>CCC(CC)(C/C=C\OC(C)(C)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C)O[Si](CC)(CC)CC,,C1CCOC1,,C1COCCOCCOCCOCCO1,[H-].[Na+],test
US20060100229A1,CCn1nc(C(N)=O)cc1CCS(C)(=O)=O>>CCn1nc(C#N)cc1CCS(C)(=O)=O,,O=P(Cl)(Cl)Cl,,[NH4+].[OH-],,test
US20120157428A1,CON(C)C(=O)c1nn(C)cc1Br.Clc1ccc([Mg]Br)cc1>>Cn1cc(Br)c(C(=O)c2ccc(Cl)cc2)n1,,C1CCOC1,,,,test
US20070072897A1,Nc1cccc(F)c1.O=[N+]([O-])c1c(F)cccc1F>>O=[N+]([O-])c1c(F)cccc1Nc1cccc(F)c1,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20060178418A1,CCI.c1ccc2c(c1)sc1ccccc12>>CCc1cccc2c1sc1ccccc12,,C1CCOC1,,Cl,[Li]CCCC,test
US20150252038A1,CC(C)(C)[Si](C)(C)Cl.COC(=O)C(c1cc(Cl)cc(Cl)c1)N1CCC(CO)CC1>>COC(=O)C(c1cc(Cl)cc(Cl)c1)N1CCC(CO[Si](C)(C)C(C)(C)C)CC1,,ClCCl,,c1c[nH]cn1,,test
US04906661,CC(C)C(=O)NCCN.COC(=O)Cc1ccccc1OCC1CO1>>CCCC(=O)NCCNCC(O)COc1ccccc1CC(=O)OC,,CO,,CCOCC,,test
US20110217311A1,CCCN.Cc1c(C(=O)O)sc2ncnc(Nc3cccnc3OC3CCC(NC(=O)OC(C)(C)C)CC3)c12>>CCCNC(=O)c1sc2ncnc(Nc3cccnc3OC3CCC(N)CC3)c2c1C,,ClCCl,,,,test
US05352684,CC(=O)C1=C(C)NC(C)=C(C(=O)CCCCCBr)C1c1cccc([N+](=O)[O-])c1.Cl.c1ccc(C2(c3ccccc3)CCNCC2)cc1>>CC(=O)C1=C(C)NC(C)=C(C(=O)CCCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1cccc([N+](=O)[O-])c1.Cl,,CC#N,,[I-].[Na+],,test
US20150259295A1,CCOC(=O)C1(c2ccc(-c3ccc(-c4cnn(C)c4N)cc3)cc2)CC1.C[C@@H](O)c1ccccc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCOC(=O)C1(c2ccc(-c3ccc(-c4cnn(C)c4NC(=O)O[C@H](C)c4ccccc4)cc3)cc2)CC1,,Cc1ccccc1,ClCCl,,,test
US06057352,CC(=O)COc1cc(Cl)cc(Cl)c1.COc1nn(C)c(=O)n1-c1ccccc1CON>>COc1nn(C)c(=O)n1-c1ccccc1CON=C(C)COc1cc(Cl)cc(Cl)c1,,c1ccncc1,,Cl,,test
US06222073B1,C=Cc1ccccc1.CNc1ccccc1>>CN(CCc1ccccc1)c1ccccc1,,CCCCCC,CCOC(C)=O,,,test
US04485107,Cl.OC1CN(Cc2ccccc2)CCC1=C(c1ccc(F)cc1)c1ccc(F)cc1>>Cl.OC1CNCCC1=C(c1ccc(F)cc1)c1ccc(F)cc1,[Pd],CO,,[H][H],,test
US20070185142A1,CC(=O)Cl.O=C1Nc2ccc(C(F)(C(F)(F)F)C(F)(F)F)cc2CN1N=Cc1cccnc1>>CC(=O)N1C(=O)N(N=Cc2cccnc2)Cc2cc(C(F)(C(F)(F)F)C(F)(F)F)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20150344429A1,CC1(/C=N/S(=O)C(C)(C)C)COC1.C[Si](C)(C)C#N>>CC1(C(C#N)NS(=O)C(C)(C)C)COC1,,C1CCOC1,,[Cs+].[F-],,test
US20110166133A1,CCCC[Sn](CCCC)(CCCC)c1cccc(F)n1.Fc1ccc(F)c(C2CCCN2c2ccc3ncc(Br)n3n2)c1>>Fc1ccc(F)c(C2CCCN2c2ccc3ncc(-c4cccc(F)n4)n3n2)c1,,Cc1ccccc1,,CCN(CC)CC,,test
US05521170,CI.Cc1ccc(-c2ccccc2C(=O)Nc2ccc(C(=O)N3CCC(=O)N(CC(=O)N4CCN(C)CC4)c4ccccc43)cc2)cc1>>Cc1ccc(-c2ccccc2C(=O)Nc2ccc(C(=O)N3CCC(=O)N(CC(=O)N4CC[N+](C)(C)CC4)c4ccccc43)cc2)cc1.[I-],,ClCCl,,,,test
US20060276433A1,COC(=O)ONC(=N)c1ccc([N+](=O)[O-])cc1>>O=c1[nH]c(-c2ccc([N+](=O)[O-])cc2)no1,,c1ccncc1,,Cl,,test
US20160185779A1,CC1Cc2[nH]nc(-c3cccs3)c2CN1C(=O)OC(C)(C)C>>CC1Cc2[nH]nc(-c3cccs3)c2CN1,,C1COCCO1,,CCOC(C)=O,,test
US20050159341A1,CCO[C@H]1O[C@H](COCCCN=[N+]=[N-])[C@H](OCCCN=[N+]=[N-])[C@H](OCCCN=[N+]=[N-])[C@H]1OCCCN=[N+]=[N-]>>CCO[C@H]1O[C@H](COCCCN)[C@H](OCCCN)[C@H](OCCCN)[C@H]1OCCCN,[Pd],CO,,,,test
US20120058988A1,Cc1ccc(-c2cc(C(N)=O)c3[nH]c4cc(N)ccc4c3c2)cn1.ClCCOCCCl>>Cc1ccc(-c2cc(C(N)=O)c3[nH]c4cc(N5CCOCC5)ccc4c3c2)cn1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20080275043A1,O=C(NC1(c2ccccc2)CCCCC1)OCc1ccccc1>>NC1(c2ccccc2)CCCCC1,[Pd],CO,,,,test
US04861785,OC[C@H](O)COc1ccc(F)cc1>>Fc1ccc(OC[C@H]2CO2)cc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US06359134B1,O=C(Cl)c1ccc(CCl)cc1.O=S(=O)(c1ccc2ccccc2c1)N1CCNCC1>>O=C(c1ccc(CCl)cc1)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1,,CCOC(C)=O,,Cl,O=C([O-])O.[Na+],test
US20120046255A1,CC(=O)c1ccc(O)c(F)c1.NOCc1ccc2nonc2c1>>CC(=NOCc1ccc2nonc2c1)c1ccc(O)c(F)c1,,CCO,,Cl,c1ccncc1,test
US05126336,CO/N=C(\C(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(/C=C/Cn3cnc4cc(O)c(O)cc43)CS[C@H]12)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>CO/N=C(\C(=O)NC1C(=O)N2C(C(=O)O)=C(/C=C/Cn3cnc4cc(O)c(O)cc43)CS[C@H]12)c1csc(N)n1,,CC(C)OC(C)C,,COc1ccccc1,O=C(O)C(F)(F)F,test
US05576343,BrBr.CC(=O)c1cc2cc(C#N)ccc2o1>>N#Cc1ccc2oc(C(=O)CBr)cc2c1,,ClCCl,,ClC(Cl)Cl,,test
US06326359B1,COC1CCC(=O)CC1.COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CN)nc32)[C@H](O)[C@@H]1O>>COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CNC4CCC(OC)CC4)nc32)[C@H](O)[C@@H]1O,,C1CCOC1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20110166121A1,CC(=O)NN.CCCc1cc2c(N3CCn4c(nnc4C(F)(F)F)C3)nc(C(=O)O)nc2s1>>CCCc1cc2c(N3CCn4c(nnc4C(F)(F)F)C3)nc(C(=O)NNC(C)=O)nc2s1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160015712A1,CC(C)(C)OC(=O)N[C@H]1C[C@@H](N)C1.COc1ccc(-n2nnc3cnc(Cl)nc32)cc1>>COc1ccc(-n2nnc3cnc(N[C@@H]4C[C@H](NC(=O)OC(C)(C)C)C4)nc32)cc1,,COCCO,,,,test
US20150223460A1,Cc1cc(-c2cc(C)n(C)n2)ccc1OCc1c(C2CC2)cccc1-n1nnn(C)c1=O.O=C1CCC(=O)N1Cl>>Cc1cc(-c2nn(C)c(C)c2Cl)ccc1OCc1c(C2CC2)cccc1-n1nnn(C)c1=O,,ClC(Cl)Cl,,,,test
US20060160876A1,CCOC(=O)CC(=O)CC.Cc1ccc2[nH]cc(CCO)c2c1>>CCOC(=O)CC1(CC)OCCc2c1[nH]c1ccc(C)cc21,,ClCCl,,CCOCC,FB(F)F,test
US20160157485A1,NC1CCC1c1ccc(Cl)cc1.O=C(Cl)c1ccccc1C(F)(F)F>>O=C(NC1CCC1c1ccc(Cl)cc1)c1ccccc1C(F)(F)F,,C1CCOC1,,CCN(CC)CC,,test
US20060111375A1,COC(=O)CCCCCCCCC(=O)c1cc(C)ccc1O.COc1cc2nccc(Cl)c2cc1OC>>COC(=O)CCCCCCCCC(=O)c1cc(C)ccc1Oc1ccnc2cc(OC)c(OC)cc12,CN(C)c1ccncc1,Clc1ccccc1Cl,,,,test
US20070232627A1,CC(C)N(C(=O)c1ccc(Sc2ccc(NC(=O)OCC(Cl)(Cl)Cl)cc2)c([N+](=O)[O-])c1)c1ccc(Br)cc1>>CC(C)N(C(=O)c1ccc(Sc2ccc(NC(=O)OCC(Cl)(Cl)Cl)cc2)c(N)c1)c1ccc(Br)cc1,[Fe],,,[Cl-].[NH4+],,test
US04613208,Nc1ccc(-c2ccc(O)cc2)cc1.O=Nc1ccc([N+](=O)[O-])cc1Cl>>O=[N+]([O-])c1ccc(N=Nc2ccc(-c3ccc(O)cc3)cc2)c(Cl)c1,,CC(=O)O,,,,test
US20140142126A1,C=C(C)c1c(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc2n1[C@@H]1CCN(C(=O)OC(C)(C)C)C1>>CC(C)c1c(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc2n1[C@@H]1CCN(C(=O)OC(C)(C)C)C1,[Pd],,,,,test
US20070105900A1,O=C(Nc1cn(C2CCCCO2)nc1CO)OCc1ccccc1>>O=Cc1nn(C2CCCCO2)cc1NC(=O)OCc1ccccc1,O=[Mn]=O,CC(C)=O,,,,test
US20140128386A1,COC(=O)[C@@H](N)CCC(F)(F)C(F)(F)F.O=C(Cl)OCc1ccccc1>>COC(=O)[C@H](CCC(F)(F)C(F)(F)F)NC(=O)OCc1ccccc1,,C1CCOC1,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20150225381A1,CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=S)N1c1ccc(OCC2(O[Si](C)(C)C(C)(C)C)CC2)c(F)c1>>CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=S)N1c1ccc(OCC2(O)CC2)c(F)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05939576,C=CCc1c(O)ccc(C(C)(C)c2ccc(O)cc2)c1CC=C>>CC(C)(c1ccc(O)cc1)c1ccc(O)cc1,,C1CCOC1,Cc1ccccc1,,,test
US20150099691A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.N#CCN>>N#CCN.N[C@H](Cc1ccccc1)C(=O)O,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05760054,CC(C)c1ccc2c(c1)C(=O)N(CCCCO)S2(=O)=O.O=c1oc2ccccc2n1C1CCNCC1>>CC(C)c1ccc2c(c1)C(=O)N(CCCCN1CCC(n3c(=O)oc4ccccc43)CC1)S2(=O)=O,,CCOC(C)=O,,,,test
US20100184989A1,Brc1ccccn1.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2ccccn2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US05387585,CCOC(=O)c1ncn2c1CNC(=O)c1sccc1-2.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)c1ncn2c1CNC(=S)c1sccc1-2,,Cc1ccccc1,,,,test
US20040235854A1,NN1CCCCC1.O=C(Cl)c1cn(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1>>O=C(NN1CCCCC1)c1cn(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1,,ClCCl,,CCN(CC)CC,,test
US20050107339A1,CCOc1cc(C(O)c2ccc(OC)c([N+](=O)[O-])c2)ccc1OC>>CCOc1cc(C(=O)c2ccc(OC)c([N+](=O)[O-])c2)ccc1OC,O=[Mn]=O,ClCCl,,,,test
US20140135332A1,CCOC(=O)C(Oc1ccc(F)c(C(N)=O)c1F)c1nc(-c2ccc(C(F)(F)F)cc2)co1>>NC(=O)c1c(F)ccc(OC(C(=O)O)c2nc(-c3ccc(C(F)(F)F)cc3)co2)c1F,,C1CCOC1,,[Na+].[OH-],,test
US20120214767A1,O=Cc1ccc2c(c1)CCc1c-2noc1-c1noc(-c2ccccc2)c1C(F)(F)F.O[C@@H]1CCNC1>>O[C@@H]1CCN(Cc2ccc3c(c2)CCc2c-3noc2-c2noc(-c3ccccc3)c2C(F)(F)F)C1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070172421A1,CN.O=Cc1ccc2c(c1)OCO2>>C/N=C/c1ccc2c(c1)OCO2,,CCO,,,,test
US06320051B1,O=c1cc(NCCC2CC=CCN2Cc2ccc(Cl)c(Cl)c2)[nH]c2ccccc12>>O=c1cc(NCCC2CCCCN2Cc2ccc(Cl)c(Cl)c2)[nH]c2ccccc12,O=[Pt]=O,CCO,,,,test
US20130196998A1,CC(C)(C)OC(=O)CCN1CCC2(CC1)COc1cc(C(=O)c3ccccc3Cl)ccc12.Cl>>Cc1ccccc1C(=O)c1ccc2c(c1)OCC21CCN(CCC(=O)O)CC1.Cl,,Cl,,C1COCCO1,,test
US06265411B1,CNS(=O)(=O)c1ccc2c(c1)CC(=O)N2.COCCOc1cc2ncnc(Cl)c2cc1OC>>CNS(=O)(=O)c1ccc2c(c1)C(c1ncnc3cc(OCCOC)c(OC)cc13)C(=O)N2.Cl,,CN(C)C=O,,[H-].[Na+],,test
US20100240634A1,O=C1CCCN1CCO.O=C1c2ccccc2-c2ncc(O)cc21>>O=C1c2ccccc2-c2ncc(OCCN3CCCC3=O)cc21,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150353581A1,CC(N)(C#N)COc1ccc2c(c1-c1ccco1)B(O)OC2.O=C(O)c1ccc(OC(F)(F)F)cc1>>CC(C#N)(COc1ccc2c(c1-c1ccco1)B(O)OC2)NC(=O)c1ccc(OC(F)(F)F)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04812583,CCC(C)(C)C(=O)Cl.CCCC(O)c1cc(C)cc(C)c1/C=C/C1OCC(C)(C)CO1>>CCCC(OC(=O)C(C)(C)CC)c1cc(C)cc(C)c1/C=C/C1OCC(C)(C)CO1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20090264445A1,CCOC(=O)/C=C(\C)Oc1cccc(Cl)c1.O=C1CCC(=O)N1Br>>CCOC(=O)/C=C(\CBr)Oc1cccc(Cl)c1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20100173793A1,COc1cccc(C(=NO)C(F)(F)F)c1.N>>COc1cccc(C2(C(F)(F)F)NN2)c1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080312216A1,COC(=O)C(C)(CCN1CCN2C(CCS2(=O)=O)C1)c1ccc(Cl)c(Cl)c1>>CC(CCN1CCN2C(CCS2(=O)=O)C1)(C(=O)O)c1ccc(Cl)c(Cl)c1,,C1CCOC1,O,[Li]O,,test
US04450164,CC(=O)C(Cl)CC#N.Nc1ncccc1OCc1ccccc1>>Cc1nc2c(OCc3ccccc3)cccn2c1CC#N,,CCO,,CCN(CC)CC,,test
US20050176706A1,CC(C)(CC(=O)C(F)(F)F)c1cc(Cl)cc2c1OCC2.C[S+](C)(C)=O>>CC(C)(CC1(C(F)(F)F)CO1)c1cc(Cl)cc2c1OCC2,,CS(C)=O,,[H-].[Na+],,test
US20040044057A1,O=C1CCCc2c1ccc(O)c2[N+](=O)[O-].O[C@@H](Cn1ccnc1)c1cccnc1>>O=C1CCCc2c1ccc(O[C@H](Cn1ccnc1)c1cccnc1)c2[N+](=O)[O-],,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060122185A1,N#Cc1n[nH]c2ncncc12.NNC(N)=S>>Nc1nnc(-c2n[nH]c3ncncc23)s1,,O=C(O)C(F)(F)F,,[NH4+].[OH-],,test
US20110136735A1,CCOC(=O)C1(O)CCC(O[Si](C)(C)C(C)(C)C)CC1>>CC(C)(C)[Si](C)(C)OC1CCC(O)(C(=O)O)CC1,,CO,,C1CCOC1,[Li+].[OH-],test
US20040147739A1,CCOC(=O)CC(C)C(F)(F)F>>CC(CCO)C(F)(F)F,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040224997A1,CCCC(CC(=O)c1ccc(Br)cc1)C(=O)OCC.O=[N+]([O-])c1ccc(B(O)O)cc1>>CCCC(CC(=O)c1ccc(-c2ccc([N+](=O)[O-])cc2)cc1)C(=O)OCC,,C1COCCO1,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20090270359A1,Cc1nn(C2CCCCO2)c(C)c1-c1ccc(C#N)c(Cl)c1>>Cc1n[nH]c(C)c1-c1ccc(C#N)c(Cl)c1,,CO,Cl,[Na+].[OH-],,test
US20100076187A1,Cc1c(Cl)nnc(I)c1C.N#C[Cu]C#N>>Cc1c(Cl)nnc(C#N)c1C,,CC#N,,ClCCl,,test
US04711905,Nc1ccc(Cl)c(Cl)c1.O=C=NC(=O)c1ccc(F)cc1Cl>>O=C(NC(=O)c1ccc(F)cc1Cl)Nc1ccc(Cl)c(Cl)c1,,Cc1ccccc1,,,,test
US20150175619A1,Brc1cnc2cc[nH]c2c1.CC(Cl)c1ccccn1>>CC(c1ccccn1)n1ccc2ncc(Br)cc21,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US04994486,BrB(Br)Br.COc1cc2c3c(c1)C[C@@H](c1ccccc1)C[C@H]3[C@H](N)CC2>>Br.N[C@@H]1CCc2cc(O)cc3c2[C@H]1C[C@H](c1ccccc1)C3,,ClCCl,,,,test
US20090170921A1,Br[Mg]c1ccccc1.COCCn1c(-c2ccc(C(C)C)cc2)nc2cc(C=O)cc(OC)c21>>COCCn1c(-c2ccc(C(C)C)cc2)nc2cc(C(O)c3ccccc3)cc(OC)c21,,C1CCOC1,,,,test
US06005128,C#Cc1ccccc1.C1CCOC1.CCN(CC)[Si](Cl)(Cl)N(CC)CC.N#C[Cu]C#N.[Li]CCCC>>CCN(CC)[Si](C#Cc1ccccc1)(C#Cc1ccccc1)N(CC)CC,,C1CCOC1,,,,test
US20120309750A1,C=C[Sn](CCCC)(CCCC)CCCC.CCNC(=O)c1noc(-c2cc(C(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)c1I>>C=Cc1c(C(=O)NCC)noc1-c1cc(C(C)C)c(OCc2ccccc2)cc1OCc1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20110040094A1,CC(C)CBr.CCOC(=O)Cc1ccc(-c2ccc(C(F)(F)F)cc2)c(OCC(F)(F)F)c1>>CCOC(=O)C(CC(C)C)c1ccc(-c2ccc(C(F)(F)F)cc2)c(OCC(F)(F)F)c1,,CN(C)C=O,O,[H-].[Na+],[Cl-].[NH4+],test
US04051141,O=C(CBr)c1ccccc1.c1cc2sccc2cn1>>O=C(C[n+]1ccc2sccc2c1)c1ccccc1.[Br-],,CC(C)=O,,,,test
US20160108039A1,COc1cc(C(=O)N2CC(C)OCC2CCO[Si](C(C)C)(C(C)C)C(C)C)cn2nc(NC(CF)c3cccc(Cl)c3)nc12>>COc1cc(C(=O)N2CC(C)OCC2CCO)cn2nc(NC(CF)c3cccc(Cl)c3)nc12,,C1CCOC1,ClCCl,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06200982B1,COC(=O)C(C(=O)c1ccncc1)c1ccc(OC)cc1>>COc1ccc(CC(=O)c2ccncc2)cc1,,CS(C)=O,,O,[Cl-].[Na+],test
US04251443,BrBr.CCC1N=C(c2ccccc2F)c2cc(N)ccc2N(C)C1=O>>CCC1N=C(c2ccccc2F)c2c(ccc(N)c2Br)N(C)C1=O,,CC(=O)O,,,,test
US20160175289A1,CC(C)(C)OC(=O)N1CC(Oc2cc(F)c(C=O)c(F)c2)C1.C[C@H](Cc1c[nH]c2ccccc12)NCC(C)(C)F>>C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(OC3CN(C(=O)OC(C)(C)C)C3)cc2F)N1CC(C)(C)F,,Cc1ccccc1,,CC(=O)O,,test
US20050101587A9,COC(Cc1ccc(Cl)cc1NC1CCN(C(=O)OC(C)(C)C)CC1)OC>>Clc1ccc2ccn(C3CCNCC3)c2c1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04152433,CCOC(=O)C(=NOC)C(=O)CBr.NC(N)=S>>Br.CCOC(=O)C(=NOC)c1csc(N)n1,,CCO,,,,test
US20020026060A1,CC(C(=O)O)c1ccc2c(c1)C(C)(C)CCC2(C)C.CI>>CC1(C)CCC(C)(C)c2cc(C(C)(C)C(=O)O)ccc21,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US06110943,CC(C)(C)OC(=O)N[C@H](CO)Cc1ccccc1.COc1ccsc1C1(O)CCNCC1>>COc1ccsc1C1(O)CCN(C[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)CC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160158207A1,Cn1cc(-c2cc3[nH]ccc3cc2Cl)cn1>>Cn1cc(-c2cc3c(cc2Cl)CCN3)cn1,,CC(=O)O,,[BH3-]C#N.[Na+],,test
US20060264415A1,CC(C)(C)[Si](C)(C)OCCBr.NCCc1c[nH]c2ccccc12>>CC(C)(C)[Si](C)(C)OCCNCCc1c[nH]c2ccccc12,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080300231A1,CC(C)(C)OC(=O)NCCC[C@H](N)C(=O)NCCNC(=O)OC(C)(C)C.O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1)C(=O)NCCNC(=O)OC(C)(C)C,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20040157890A1,CC(=O)c1ccc(C(F)(F)F)cc1.COC(C)(OC)N(C)C>>CC(=CC(=O)c1ccc(C(F)(F)F)cc1)N(C)C,,CCOCC,,,,test
US20100173944A1,CCCO.Cc1c(Cl)cc[n+]([O-])c1C>>CCCOc1cc[n+]([O-])c(C)c1C,,CS(C)=O,O,[Na+].[OH-],,test
US20070088041A1,COc1nnc(-c2ccncc2)cc1-c1cc2ccccc2n1C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>COc1nnc(-c2ccncc2)cc1-c1cc2ccccc2[nH]1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US05089505,BrP(Br)Br.OCCc1ccc2c(c1)CCO2>>BrCCc1ccc2c(c1)CCO2,,ClC(Cl)(Cl)Cl,,,,test
US04728458,CCCCCCCCC(=O)Oc1ccc(C(=O)O)cc1.O=S(Cl)Cl>>CCCCCCCCC(=O)Oc1ccc(C(=O)Cl)cc1,,ClC(Cl)(Cl)Cl,,,,test
US20050227959A1,CN(CCc1ccc(F)cc1)S(=O)(=O)c1cc(Cl)sc1Cl>>CN(CCc1ccc(F)cc1)S(=O)(=O)c1csc(Cl)c1,,C1CCOC1,O,[Cl-].[NH4+],,test
US20130210844A1,CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)O)c1.Nc1cccc2c(Nc3ccc(C(F)(F)F)cc3F)nccc12>>CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)Nc2cccc3c(Nc4ccc(C(F)(F)F)cc4F)nccc23)c1,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US06200998B1,C=[N+]=[N-].O=C(Cl)CCc1ccccc1>>[N-]=[N+]=CC(=O)CCc1ccccc1,,CC(=O)O,,,,test
US05591729,O=C1CC2Cc3ccccc3C2=NN1.O=C=Nc1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc(C(F)(F)F)cc1)N1CCC2Cc3ccccc3C2=N1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],[Cl-].[NH4+],test
US20110098302A1,CI.COc1cccc(CC#N)c1>>COc1cccc(C(C)C#N)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20040147543A1,CC(C)N=C=O.CCCCc1nc2c(N)nc3cc(-c4cccnc4)ccc3c2n1CCN>>CCCCc1nc2c(N)nc3cc(-c4cccnc4)ccc3c2n1CCNC(=O)NC(C)C,,ClC(Cl)Cl,,,,test
US20050107364A1,CC(=O)Nc1ccc2cc(S(=O)(=O)Cl)ccc2c1.CC(C)CC[C@@]1(C)C(=O)C(C2=NS(=O)(=O)c3cc(N)ccc3N2)=C(O)c2ccccc21>>CC(=O)Nc1ccc2cc(S(=O)(=O)Nc3ccc4c(c3)S(=O)(=O)N=C(C3=C(O)c5ccccc5[C@@](C)(CCC(C)C)C3=O)N4)ccc2c1,,CC(C)=O,,Cl,c1ccncc1,test
US20150119373A1,CC(C)(C)OC(=O)N1CCC(O)CC1.COCCOS(=O)(=O)c1ccc(C)cc1>>COCCOC1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,ClCCl,[H-].[Na+],,test
US20090124616A1,BrCCCOc1cccc2ccccc12.CCOC(=O)c1[nH]c2ccc(OCc3ccccc3)cc2c1Br>>CCOC(=O)c1c(Br)c2cc(OCc3ccccc3)ccc2n1CCCOc1cccc2ccccc12,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090163463A1,CC(=O)Cl.Cc1nc(N)ncc1-c1ccc(Cl)c(S(=O)(=O)NC2CCC(CN)CC2)c1>>CC(=O)NCC1CCC(NS(=O)(=O)c2cc(-c3cnc(N)nc3C)ccc2Cl)CC1,,c1ccncc1,,,,test
US20030119748A1,CC(C)[C@H](NC(=O)c1cc2ccccc2n1CC(=O)OC(C)(C)C)C(=O)NC(CC(=O)OC(C)(C)C)C(O)COc1c(F)c(F)cc(F)c1F>>CC(C)[C@H](NC(=O)c1cc2ccccc2n1CC(=O)OC(C)(C)C)C(=O)NC(CC(=O)OC(C)(C)C)C(=O)COc1c(F)c(F)cc(F)c1F,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20150307507A1,COC(=O)c1ccc(-c2cc(C)nnc2C)s1>>Cc1cc(-c2ccc(C(=O)O)s2)c(C)nn1,,C1CCOC1,O,[Li]O,,test
US05565451,ClCCl.O=[N+]([O-])c1cccc(COc2ccc3ccccc3c2)c1>>Cl.Nc1cccc(COc2ccc3ccccc3c2)c1,[Fe],CC(=O)O,O,,,test
US06022895,Brc1ccccc1.O=C1CCCc2ccc(O)cc21>>O=C1CCCc2ccc(Oc3ccccc3)cc21,O=[Cu],c1ccncc1,,O=C([O-])[O-].[K+].[K+],,test
US20160002204A1,N#CCCCCBr.O=C(Cc1ccccc1)Nc1cc[nH]c(=O)n1>>N#CCCCCn1ccc(NC(=O)Cc2ccccc2)nc1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06399629B1,COC(=O)[C@@H]1C[C@H](OS(=O)(=O)c2ccc(C)cc2)CN1C(=O)OC(C)(C)C.[C-]#N>>COC(=O)[C@@H]1C[C@@H](C#N)CN1C(=O)OC(C)(C)C,,CN(C)C=O,,O,,test
US09248117B2,CC1(C)CN(CCOS(C)(=O)=O)C(=O)N1.CNC>>CN(C)CCN1CC(C)(C)NC1=O,,C1CCOC1,,,,test
US20110306541A1,CC(C)(C)OC(=O)N1[C@H](C(=O)Nc2ccc(Br)cc2N)[C@H]2CC[C@@H]1C2>>CC(C)(C)OC(=O)N1[C@H](c2nc3ccc(Br)cc3[nH]2)[C@H]2CC[C@@H]1C2,,CCO,,,,test
US04327022,CCC(C#N)(CC)P(=O)(O)O.COc1ccc2c(c1)CC(=O)CC2>>COc1ccc2c(c1)C=C(CC#N)CC2,,COCCOC,,[H-].[Na+],,test
US20110281868A1,C[Si](C)(C)CCOCn1nc(-c2cn[nH]c2)c2ccc(Br)cc21.ClCCN1CCCC1>>C[Si](C)(C)CCOCn1nc(-c2cnn(CCN3CCCC3)c2)c2ccc(Br)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20040127426A1,CCC(NC(=O)C(CC1CCCCC1)NC(=NS(C)(=O)=O)c1ccccc1)C(O)c1nc2ccccc2o1>>CCC(NC(=O)[C@H](CC1CCCCC1)NC(=NS(C)(=O)=O)c1ccccc1)C(=O)c1nc2ccccc2o1,,C1CCOC1,CCOC(C)=O,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US06762178B2,CC#CCOc1ccc(S(=O)(=O)N(C)c2c(CN3CCN(C)CC3)cc(-c3ccccc3)cc2C(=O)OC)cc1>>CC#CCOc1ccc(S(=O)(=O)N(C)c2c(CN3CCN(C)CC3)cc(-c3ccccc3)cc2C(=O)O)cc1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US06017467,BrC(Br)(Br)Br.CCCC(C)(C)[SiH2]Oc1ccc(C=O)c(F)c1>>CCCC(C)(C)[SiH2]Oc1ccc(C=C(Br)Br)c(F)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US05236936,Cc1cc(OCc2ccc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc2)c(-c2ccncc2)c(C)n1.O>>Cc1cc(OCc2ccc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc2)c(CO)c(C)n1,,C1CCOC1,,[BH4-].[Li+],,test
US06716865B1,CCN(CC)CC.COc1ccc2sc(CC3(O)C4CC5CC(C4)CC3C5)nc2c1>>COc1ccc2sc(C=C3CCCCCC3)nc2c1,,CCOC(C)=O,ClCCl,CS(=O)(=O)Cl,,test
US05831072,O=C(OC[C@H]1O[C@@H](n2cnc(C(=O)CCl)c2N2C(=O)c3ccccc3C2=O)[C@@H](F)[C@@H]1OC(=O)c1ccccc1)c1ccccc1>>Nc1c(C(=O)CCl)ncn1[C@@H]1O[C@H](COC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)[C@@H]1F,,ClCCl,,NN,O,test
US20150344490A1,CCC(=O)c1ccc(O)cc1C.Clc1nccc2occc12>>CCC(=O)c1ccc(Oc2nccc3occc23)cc1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05496834,CC(=O)O[C@@H]1OCC[C@@H]1NC(=O)[C@H](CC(C)C)NS(=O)(=O)c1ccc([N+](=O)[O-])cc1>>CC(=O)O[C@@H]1OCC[C@@H]1NC(=O)[C@H](CC(C)C)NS(=O)(=O)c1ccc(N)cc1,,CCO,,,,test
US04053606,C=Cc1cnc(C)c(O)c1CO.ClCc1ccccc1>>C=Cc1cnc(C)c(OCc2ccccc2)c1CO,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080306122A1,Cl.NC(=O)[C@@H]1CC[C@H](c2ccc(CCc3ccccc3)cc2)N1>>Cl.NC(=O)[C@@H]1CC[C@H](c2ccc(CCc3ccccc3)cc2)N1,,CCOCC,,,,test
US20030158225A1,CC1CNC(C)CN1.ClCc1ccc(Cl)c(Cl)c1>>CC1CN(Cc2ccc(Cl)c(Cl)c2)C(C)CN1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US20120071461A1,COC(=O)c1ccc2c(c1)[C@H](N)CCO2.O=C(Cl)c1ccccc1Cl>>COC(=O)c1ccc2c(c1)[C@H](NC(=O)c1ccccc1Cl)CCO2,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20100152265A1,BrCc1ccccc1.CCOC(=O)c1nn(C2CCCCO2)c2cc(O)ccc12>>CCOC(=O)c1nn(C2CCCCO2)c2cc(OCc3ccccc3)ccc12,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05491172,CC(C)c1cc(C(C)C)c(CBr)c(C(C)C)c1.CC(C)c1cccc(C(C)C)c1OS(=O)(=O)N=C=O>>CC(C)c1cc(C(C)C)c(CC(=O)c2ccc(C(C)C)c(OS(N)(=O)=O)c2C(C)C)c(C(C)C)c1,,C1CCOC1,,CCOC(C)=O,[Cl-].[NH4+],test
US20070208054A1,CCOc1cc(Br)ccc1CCO.N#Cc1cccc(N=C=O)c1>>CCOc1cc(Br)ccc1CCOC(=O)Nc1cccc(C#N)c1,,C1CCOC1,,[H-].[Na+],,test
US20040259957A1,CCOc1ccc(C=O)cc1O.COc1cc(OC)cc(C(C)=O)c1>>CCOc1ccc(/C=C/C(=O)c2cc(OC)cc(OC)c2)cc1O,,CO,,[Na+].[OH-],,test
US05348965,CCOC(=O)[C@@H]1CCCN(CCOCC=C2c3ccccc3CCc3ccccc32)C1.Cl>>Cl.O=C(O)[C@@H]1CCCN(CCOCC=C2c3ccccc3CCc3ccccc32)C1,,CCO,,ClCCl,[Na+].[OH-],test
US20080280875A1,CCOC(=O)c1cc(Oc2ccc(S(C)(=O)=O)cc2)c2cc(C=O)oc2c1>>CCOC(=O)c1cc(Oc2ccc(S(C)(=O)=O)cc2)c2cc(CO)oc2c1,,CO,,[BH4-].[Na+],,test
US20060217382A1,COc1ccc(Nc2ncc(C(C)NC(=O)C3CCCCC3)nn2)cc1>>COc1ccc(Nc2ncc3c(C)nc(C4CCCCC4)n3n2)cc1,,ClCCCl,,O=P(Cl)(Cl)Cl,,test
US05171860,CCOC1=NS(=O)(=O)C(C#N)=C1Cl.C[Si](C)(C)N[Si](C)(C)C>>CCOC1=NS(=O)(=O)C(C#N)=C1N,,CCO,,,,test
US20020055631A1,COC(=O)c1ccc(-c2ccc(CCO)cc2OC)cc1>>COC(=O)c1ccc(-c2ccc(CC=O)cc2OC)cc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05204344,CC(C)(C)CC(=O)Cl.CCC(CC)(Cc1cc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Cl)cc1)C(=O)OC>>CCC(CC)(Cc1c(C(=O)CC(C)(C)C)c2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Cl)cc1)C(=O)OC,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100137276A1,NCC1CCCO1.O=S(=O)(Cl)c1ccc(I)cc1>>O=S(=O)(NCC1CCCO1)c1ccc(I)cc1,,ClCCl,,CCN(CC)CC,,test
US20060094767A1,C[C@](O)(COC(=O)N1CCc2cc(Cl)ccc21)Cn1cc([N+](=O)[O-])nc1Cl>>C[C@]1(COC(=O)N2CCc3cc(Cl)ccc32)Cn2cc([N+](=O)[O-])nc2O1,,CN(C)C=O,,[H-].[Na+],,test
US20100158818A1,CI.CN(C)CCN(C)C(=O)CC(C)(C)NC(=O)OCc1ccccc1>>CN(CC[N+](C)(C)C)C(=O)CC(C)(C)NC(=O)OCc1ccccc1.[I-],,CCO,,,,test
US20130274255A1,CC1(C)OB(c2ccc(F)c(F)c2)OC1(C)C.COc1ccc(-c2nn(COCC[Si](C)(C)C)c3c2Cc2sc(Br)cc2-3)cc1>>COc1ccc(-c2nn(COCC[Si](C)(C)C)c3c2Cc2sc(-c4ccc(F)c(F)c4)cc2-3)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20120231462A1,CCCC[Sn](CCCC)(CCCC)c1nccn1S(=O)(=O)N(C)C.Cc1ccccc1C(=O)OC[C@H]1O[C@@H](n2ccc3c(I)ccnc32)C[C@@H]1OC(=O)c1ccccc1C>>CN(C)S(=O)(=O)n1ccnc1-c1ccnc2c1ccn2[C@H]1C[C@H](O)[C@@H](CO)O1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,[Cl-].[Li+],,test
US05952354,O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.O=C(Oc1ccc(Oc2ccccc2)cc1)N1CCC(O)CC1>>O=C(Oc1ccc([N+](=O)[O-])cc1)OC1CCN(C(=O)Oc2ccc(Oc3ccccc3)cc2)CC1,,ClCCl,,c1ccncc1,,test
US20020037918A1,C/C(=C\C=C\CCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)CCC1OCCO1>>C/C(=C\C=C\CCCO)CCC1OCCO1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20020183311A1,CCOC(C)=O.Cc1cc(C(=O)N2Cc3ccc(C(=O)N(C)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)n3Cc3ccccc32)ccc1C1=CCCCC1>>Cc1cc(C(=O)N2Cc3ccc(C(=O)N(C)C[C@H](O)[C@H]4OC(=O)O[C@@H]4[C@H](O)CO)n3Cc3ccccc32)ccc1C1=CCCCC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04203988,CN(C)CCN.CN(C)Cc1cccc(Cl)n1>>CN(C)CCNc1cccc(CN(C)C)n1,,c1ccncc1,,[Na+].[OH-],,test
US04025641,BrCCCCBr.CSc1ccc(O)cc1>>CSc1ccc(OCCCCBr)cc1,,CN(C)C=O,,O,[K+].[OH-],test
US20100048715A1,CCN.Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1cc([N+](=O)[O-])ccc1F>>CCNc1ccc([N+](=O)[O-])cc1C(=O)Nc1c(C)cc(C(F)(C(F)(F)F)C(F)(F)F)cc1C,,CC#N,,O,,test
US20080287477A1,COC(=O)C1Cc2cccc(S(=O)(=O)N(C)CCON=C(c3ccc(C)cc3)c3ccc(C)cc3)c2C1>>Cc1ccc(C(=NOCCN(C)S(=O)(=O)c2cccc3c2CC(C(=O)O)C3)c2ccc(C)cc2)cc1,,C1CCOC1,CO,[Li+].[OH-],,test
US20070106095A1,CC(C)(C)C(=O)CBr.CCC(CC)(c1ccc(O)c(C)c1)c1cc2cc(C(=O)OC)ccc2o1>>CCC(c1cc2cc(C(=O)OC)ccc2o1)C(C)c1ccc(OCC(=O)C(C)(C)C)c(C)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100234395A1,CNO.COc1ccc(-c2nc(N3CCNCC3)sc2-c2ccc(OC)cc2)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc(-c2nc(N3CCN(C(=O)N(C)O)CC3)sc2-c2ccc(OC)cc2)cc1,,C1CCOC1,,CCN(CC)CC,Cl,test
US04335122,CN(C)CCCC1(C#N)c2ccccc2COc2ccccc21.Cl>>CN(C)CCCC1(C#N)c2ccccc2COc2ccccc21.Cl,,CCOCC,,,,test
US20110257165A1,COc1cccc(C(=O)C(=C2SCS2)c2ccncc2)c1.NN>>COc1cccc(-c2n[nH]c(S)c2-c2ccncc2)c1,,C1CCOC1,,,,test
US20130338140A1,COc1ccc(CNC(c2ccc(Cl)c(Cl)c2)C(F)(F)F)cc1OC>>NC(c1ccc(Cl)c(Cl)c1)C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140275011A1,CN(CCCN)c1ccccn1.Fc1cccc(Cn2cnc3ccc(-c4cc(F)ncc4Cl)cc32)c1>>CN(CCCNc1cc(-c2ccc3ncn(Cc4cccc(F)c4)c3c2)c(Cl)cn1)c1ccccn1,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US07897607B2,COC(=O)CC(=O)c1c(F)cccc1Cl.CS(=O)(=O)N=[N+]=[N-]>>COC(=O)C(=[N+]=[N-])C(=O)c1c(F)cccc1Cl,,CC#N,,CCN(CC)CC,,test
US04410509,CCCC(=O)Cl.CCCCCCCC/C=C\CCCCCCCCO>>CCCCCCCC/C=C\CCCCCCCCOC(=O)CCC,,CCOCC,,c1ccncc1,,test
US04018922,CC1(OCCO)CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1.Cl>>CC1(OCCO)CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1.Cl,,CC(C)=O,,CCOCC,,test
US20080287409A1,COc1cc(OCc2sc(-c3ccc(C(F)(F)F)cc3)nc2CSC)ccc1-c1noc(=O)[nH]1.O=S([O-])OO>>COc1cc(OCc2sc(-c3ccc(C(F)(F)F)cc3)nc2CS(C)(=O)=O)ccc1-c1noc(=O)[nH]1,,CC#N,,O,,test
US05004747,CC(C)c1c(C(=O)O)oc(=O)c2ccccc12.Nc1ccc(F)cc1>>CC(C)c1c(C(=O)O)n(-c2ccc(F)cc2)c(=O)c2ccccc12,,CCOCC,,,,test
US20100004269A1,COC(=O)c1cc(F)c(CNC=O)nc1Nc1ccc([Si](C)(C)C)cc1F.O=C1CCC(=O)N1Br>>COC(=O)c1cc(F)c(CNC=O)nc1Nc1ccc(Br)cc1F,,ClCCl,,,,test
US20040266789A1,COC(=O)C(N)CSCc1ccc(-c2ccc(-c3cccc4c3oc3ccccc34)cc2)cc1.O=C(O)c1cc(C(F)(F)F)ccc1F>>COC(=O)C(CSCc1ccc(-c2ccc(-c3cccc4c3oc3ccccc34)cc2)cc1)NC(=O)c1cc(C(F)(F)F)ccc1F,,ClCCl,O,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US20140275061A1,CC(=O)c1ccc(Cl)cc1/C=C/C(=O)OC(C)(C)C>>CC(=O)c1ccc(Cl)cc1/C=C/C(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100330064A1,C=CC=O.CC(C)(C)OC(=O)C1CCCC1=O>>CC(C)(C)OC(=O)[C@]1(CCC=O)CCCC1=O,,ClCCl,,,,test
US05610293,COC(=O)CN(CCN(CCN(CC(=O)OC)S(=O)(=O)c1ccc(C)cc1)S(=O)(=O)c1ccc(C)cc1)S(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)N(CCN(CC(=O)O)S(=O)(=O)c2ccc(C)cc2)CCN(CC(=O)O)S(=O)(=O)c2ccc(C)cc2)cc1,,C1CCOC1,,[Na+].[OH-],,test
US20160068531A1,CS(=O)(=O)CCNc1c(F)cc(Cl)cc1[N+](=O)[O-]>>CS(=O)(=O)CCNc1c(N)cc(Cl)cc1F,[Ni],CO,,,,test
US20150197509A1,CC1(C)OB(c2ccc(C(F)(F)F)nc2)OC1(C)C.NCc1cc(F)cc(Br)c1>>NCc1cc(F)cc(-c2ccc(C(F)(F)F)nc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20030166639A1,CN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3cnccn3)c2)cc1C(F)(F)F>>CN(C)c1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3cnccn3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150336942A1,NNC(=O)C1CC1.Nc1ncc(Br)cc1C(=O)O>>Nc1ncc(Br)cc1-c1nnc(C2CC2)o1,,O=P(Cl)(Cl)Cl,,O,O=C([O-])O.[Na+],test
US20150266878A1,CC(C)C(=O)Cl.NC[C@H](Nc1cncc(Br)c1)c1ccccc1>>CC(C)C(=O)NC[C@H](Nc1cncc(Br)c1)c1ccccc1,,ClCCl,O,CCN(C(C)C)C(C)C,,test
US05349067,CN(C)c1ccccc1.Cc1ccc(S(=O)(=O)Cl)cc1.OCc1ccccc1>>C[N+](C)(Cc1ccccc1)c1ccccc1.Cc1ccc(S(=O)(=O)[O-])cc1,,C1CCOC1,,CCN(CC)CC,,test
US05556864,COc1cccc(CCc2ccccc2OCCC2CCCCN2C(=O)OC(C)(C)C)c1.Cl>>COc1cccc(CCc2ccccc2OCCC2CCCCN2)c1.Cl,,C1COCCO1,,,,test
US20110190351A1,COC(=O)c1ccc(OC)c(N)c1.O=C(O)c1cccs1>>COC(=O)c1ccc(OC)c(NC(=O)c2cccs2)c1,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20160193218A1,CC(O)C(=O)O.COc1cc(OC)c2c(=O)[nH]c(-c3ncccc3NC3CCNCC3)nc2c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ncccc3NC3CCN(C(=O)C(C)O)CC3)nc2c1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20150051199A1,CC[C@@H](NC(CC#N)C(C)C)c1ccc(Cl)c(C(=O)c2ccc(N)nc2)c1F.O=S(=O)(O)O>>CC[C@@H](N[C@H](CC(N)=O)C(C)C)c1ccc(Cl)c(C(=O)c2ccc(N)nc2)c1F,,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20050038035A1,NCCc1ccccn1.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>O=C(NCCc1ccccn1)c1ccc([N+](=O)[O-])cc1,,C1CCOC1,O,CCN(CC)CC,CCOC(C)=O,test
US20160207034A1,COc1ccc(Cl)nn1.OB(O)c1ccsc1>>COc1ccc(-c2ccsc2)nn1,[Pd],CCO,,[K+].[OH-],,test
US20130296302A1,O=Cc1nn(C2CCCCO2)c2ncc(Br)cc12.OB(O)c1cccnc1>>O=Cc1nn(C2CCCCO2)c2ncc(-c3cccnc3)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20090181947A1,O=C1CC2OC(=O)C=C2N(Cc2ccc(Cl)nc2)C1>>O=C1C=C2C(CC(O)CN2Cc2ccc(Cl)nc2)O1,,CO,,Cl,[BH4-].[Na+],test
US20130079313A1,CC(C)(C)OC(=O)CC(=O)O.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>CC(C)(C)OC(=O)CC(=O)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20090062353A1,CS(=O)(=O)Cl.OCCOc1cccc(Br)c1>>CS(=O)(=O)OCCOc1cccc(Br)c1,,ClCCl,,CCN(CC)CC,,test
US05817652,CCCCC1(CC)CN1.COC(=O)c1ccccc1S>>CCCCC1(CC)CSc2ccccc2C(=O)N1,,CO,,,,test
US06277878B1,N#C[O-].Nc1c(C(=O)c2ccccc2)[nH]c2cc(Cl)ccc12>>NC(=O)Nc1c(C(=O)c2ccccc2)[nH]c2cc(Cl)ccc12,,CC(=O)O,,O=C([O-])O.[Na+],,test
US20100137362A1,CNN(C)C(=O)c1nc(Cl)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl.COC(=O)Cl>>COC(=O)N(C)N(C)C(=O)c1nc(Cl)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl,,c1ccncc1,,,,test
US20020115727A1,C1CCOC1.N#CC1(c2ccc(Cl)cc2)CC(O)C1>>O=CC1(c2ccc(Cl)cc2)CC(O)C1,,CCCCCC,,,,test
US20050113347A1,CCOC(=O)c1cn(-c2cc(F)c(N3CCSCC3)c(F)c2)nn1>>OCc1cn(-c2cc(F)c(N3CCSCC3)c(F)c2)nn1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040220238A1,CON=C1C[C@@H](C(=O)NN)N(C(=O)OC(C)(C)C)C1.S=C=S>>CON=C1C[C@@H](c2n[nH]c(=S)o2)N(C(=O)OC(C)(C)C)C1,,CCO,,[K+].[OH-],,test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(/C=C/c2ccccc2)nc1-c1ccccc1>>CCCC(C(=O)O)c1c(C)nc(/C=C/c2ccccc2)nc1-c1ccccc1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20020151535A1,CC(C)(C)OC(=O)C[C@@H](CCCC1CCCCC1)C(=O)O/N=C(\N)C1CN(C(c2ccccc2)c2ccccc2)C1>>CC(C)(C)OC(=O)C[C@@H](CCCC1CCCCC1)c1nc(C2CN(C(c3ccccc3)c3ccccc3)C2)no1,,Cc1ccccc1,,,,test
US20140309210A1,N#Cc1cccc(CBr)c1.O=[N+]([O-])c1cn[nH]c1>>N#Cc1cccc(Cn2cc([N+](=O)[O-])cn2)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US07176231B2,CC(=O)c1ccc2c(c1)C(=C(O)c1cnccn1)C(=O)N2C(C)=O.ClC(Cl)(Cl)Cl>>CC(=O)c1ccc2c(c1)C(=C(Cl)c1cnccn1)C(=O)N2C(C)=O,,C1COCCO1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150344437A1,COC(=O)CC(=O)c1ccc(SC)cc1.NNc1ccccc1>>CSc1ccc(-c2cc(O)n(-c3ccccc3)n2)cc1,,CCO,,,,test
US20080293711A1,O=C(OCc1ccccc1)N1CCCN1C(=O)c1ccc(CN(Cc2ccccn2)Cc2ncc[nH]2)cc1>>O=C(c1ccc(CN(Cc2ccccn2)Cc2ncc[nH]2)cc1)N1CCCN1,[Pd],CO,,,,test
US20160244415A1,COc1ccc(-n2cc(C#N)c(=O)[nH]c2=O)cc1OC.Cc1c(CBr)cccc1C(F)(F)F>>COc1ccc(-n2cc(C#N)c(=O)n(Cc3cccc(C(F)(F)F)c3C)c2=O)cc1OC,,CC#N,CCOC(C)=O,[I-].[K+],,test
US20070078122A1,CN(C)S(N)(=O)=O.N=C=N.O=C(O)c1ccc2cc3n(c2c1)CC=Cc1ccccc1-3>>NC(=O)C1=Cc2ccccc2-c2cc3ccc(C(N)=O)cc3n2C1,CN(C)c1ccncc1,,,CN(C)C=O,,test
US04971620,CC(=O)O.Cc1ccc(C)c(S(=O)(=O)N(C)CC2(c3ccccc3)CO2)c1>>CC(=O)OCC(O)(CN(C)S(=O)(=O)c1cc(C)ccc1C)c1ccccc1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20130203727A1,Cc1cc2ccc(C#CC(C)(C)O)cc2c(-c2ccc(Cl)cc2)c1C(OC(C)(C)C)C(=O)O>>Cc1cc2ccc(CCC(C)(C)O)cc2c(-c2ccc(Cl)cc2)c1C(OC(C)(C)C)C(=O)O,[Rh],CCO,,,,test
US06291457B1,C[C@H](Nc1cc(-c2c(-c3cccc(C(F)(F)F)c3)nc(CCNC(=O)OCc3ccccc3)n2C)ccn1)c1ccccc1>>C[C@H](Nc1cc(-c2c(-c3cccc(C(F)(F)F)c3)nc(CCN)n2C)ccn1)c1ccccc1,[Pd],CCO,,,,test
US20160002175A1,CCC(N)COC.Nc1nc(Cl)cc(Cl)n1>>CCC(COC)Nc1cc(Cl)nc(N)n1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20140357673A1,CCCC(NC(=O)CC#N)c1ccc(OCCN(CC)CC)cc1.O=Cc1cccc(Br)n1>>CCCC(NC(=O)/C(C#N)=C/c1cccc(Br)n1)c1ccc(OCCN(CC)CC)cc1,,CCO,CCOC(C)=O,O,,test
US20040087588A1,Cc1c(C=O)c(=O)n(-c2ccccc2)n1C.NCCCNc1n[nH]c(=O)c2ccccc12>>Cc1c(C=NCCCNc2n[nH]c(=O)c3ccccc23)c(=O)n(-c2ccccc2)n1C,,CC(=O)O,,CN(C)C=O,,test
US20070032530A1,COC(=O)c1cncc(Br)c1.OB(O)c1ccc(OC(F)(F)F)cc1>>COC(=O)c1cncc(-c2ccc(OC(F)(F)F)cc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060030612A1,CON(C)C(=O)c1cccc(C(F)(F)F)c1F.Fc1ccc([Mg]Br)cc1>>O=C(c1ccc(F)cc1)c1cccc(C(F)(F)F)c1F,,C1CCOC1,,CCOCC,,test
US20100280048A1,CCOC(C#Cc1nc(C(=O)OC)c(=O)n(-c2cccc(C(F)(F)F)c2)c1C)OCC.N#Cc1ccc(NN)cc1>>COC(=O)c1nc(C#CC=NNc2ccc(C#N)cc2)c(C)n(-c2cccc(C(F)(F)F)c2)c1=O,,CO,,Cl,O,test
US20150322008A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.N#CCc1ccc(Cl)nc1>>CC(C)(C)OC(=O)N1CCC(=C(C#N)c2ccc(Cl)nc2)CC1,,CO,,O,C[O-].[Na+],test
US05703096,O=C1NC(=O)C(Cc2ccc(OCCON3C(=O)c4ccccc4C3=O)cc2)S1>>NOCCOc1ccc(CC2SC(=O)NC2=O)cc1,,CCO,,NN,O,test
US20130261106A1,CC(C)Oc1cc(CN2CCN(C)CC2)ccc1[N+](=O)[O-]>>CC(C)Oc1cc(CN2CCN(C)CC2)ccc1N,[Pd],CCO,,,,test
US20120232056A1,COC(=O)c1ccc2nc(-c3ccc(F)nc3)c(N(C)C(C)C)nc2c1>>CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1ccc(F)nc1,,C1CCOC1,O,Cl,[Li]O,test
US20030069424A1,CN1CCNCC1.NC(=O)Cc1nc(Cl)nc2ccccc12>>CN1CCN(c2nc(CC(N)=O)c3ccccc3n2)CC1,,CN1CCCC1=O,,CCOC(C)=O,,test
US04217357,C=O.CC(C)c1cc2ccccc2[nH]1.CNC>>CC(C)c1[nH]c2ccccc2c1CN(C)C,,CC(=O)O,CCO,O=C([O-])[O-].[K+].[K+],,test
US20090124652A1,CC(C)Cn1cnc2c(N)nc3cccnc3c21.CC(C)O.CCS(=O)(=O)O>>CC(C)Cn1cnc2c(N)nc3cccnc3c21.CCS(=O)(=O)O.O,,CC(C)O,,,,test
US05493030,C=CC(=O)C(C)=CCc1c(OC)c(C)c2c(c1OS(=O)(=O)c1ccc(C)cc1)C(=O)OC2>>COc1c(C)c2c(c(OS(=O)(=O)c3ccc(C)cc3)c1CC1=C(C)C(=O)CC1)C(=O)OC2,,CCOC(C)=O,ClCCl,CCOCC,FB(F)F,test
US20150105370A1,CC[C@H](Cl)C(=O)O.NC[C@@H](O)COCc1ccccc1>>CC[C@H](Cl)C(=O)NC[C@@H](O)COCc1ccccc1,CN(C)c1ccncc1,CN(C)C=O,,ClCCCl,,test
US05262415,CSC(=NC#N)SC.Nc1ccncc1N>>CSC(=NC#N)Nc1cnccc1N,,c1ccncc1,,,,test
US20150315188A1,Cc1ccc2c(c1)c1c(n2CC(OS(C)(=O)=O)c2ccncc2)CCN2CCCC12>>Cc1ccc2c(c1)c1c(n2/C=C/c2ccncc2)CCN2CCCC12,,CN1CCCC1=O,,[K+].[OH-],,test
US20080280876A1,CC(C)Oc1ccc(C(=N)NO)cc1Cl.O=C(Cl)c1ccncc1Cl>>CC(C)Oc1ccc(-c2noc(-c3ccncc3Cl)n2)cc1Cl,,c1ccncc1,,,,test
US05563143,COc1ccc(C2CNC(=O)NC2)cc1O.OCCCCc1ccccc1>>COc1ccc(C2CNC(=O)NC2)cc1OCCCCc1ccccc1,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04596819,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)CC(CNCC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1>>CC(C)C[C@@H](CN(CC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)NC(=O)OCc1ccccc1,,ClCCl,,,,test
US20060052447A1,COc1ccc(OC)c(C(C)=O)c1.O=[Se]=O>>COc1ccc(OC)c(C(=O)C=O)c1,,C1COCCO1,,O,,test
US20090306139A1,COB(C)OC.Cc1cc(Br)ccc1OC(F)(F)F>>Cc1cc(B(O)O)ccc1OC(F)(F)F,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US05037819,CC(=O)OC1NC(=O)C1CCCNC(=NC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1.CCS>>CCS[C@@H]1NC(=O)[C@H]1CCCNC(=NC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US05482936,CCOCn1c(CCCCCl)nc2c(N(Cc3ccccc3)Cc3ccccc3)nc3ccccc3c21>>ClCCCCc1nc2c(N(Cc3ccccc3)Cc3ccccc3)nc3ccccc3c2[nH]1,,Cl,,CO,,test
US20100249101A1,CCOC(=O)CC(=O)Nc1ccc(C(=N)NO)cc1>>N=C(N)c1ccc(NC(=O)CC(=O)O)cc1,,CC(=O)O,,O=C[O-].[NH4+],,test
US03997557,C1=C(N2CCCC2)CCCCC1.O.O=C(CBr)c1ccc(F)cc1>>O=C(CC1CCCCCC1=O)c1ccc(F)cc1,,O,,CN(C)C=O,,test
US20120034270A1,CCCCCCCCc1ccc2c(c1)CCN(C(=O)C(F)(F)F)C2>>CCCCCCCCc1ccc2c(c1)CCNC2,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20060116515A1,CC(C)(C)OC(=O)N(CCCBr)Cc1ccc2c(c1)OCO2.CCOC(=O)Cc1nc(-n2ccnc2)ns1>>CCOC(=O)C(CCCN(Cc1ccc2c(c1)OCO2)C(=O)OC(C)(C)C)c1nc(-n2ccnc2)ns1,,CS(C)=O,,O,[H-].[Na+],test
US05506361,CCCCc1nc2c(n1Cc1ccc(-c3ccccc3C(=O)OC(C)(C)C)cc1)C(=O)C(C)=C(C)C2=O>>CCCCc1nc2c(n1Cc1ccc(-c3ccccc3C(=O)O)cc1)C(=O)C(C)=C(C)C2=O,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20120270203A1,Cc1cc(C#Cc2ccccc2)c(N)c([N+](=O)[O-])c1>>Cc1cc([N+](=O)[O-])c2[nH]c(-c3ccccc3)cc2c1,,C1CCOC1,CN1CCCC1=O,O,CC(C)(C)[O-].[K+],test
US20020022729A1,Cc1csc2c1C(=O)CCC2.O=C1CCC(=O)N1Br>>Cc1c(Br)sc2c1C(=O)CCC2,,ClCCl,,O,,test
US20030212055A1,CC(=O)N1CCN(CCCO)CC1.COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)cnnc2cc1O>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)cnnc2cc1OCCCN1CCN(C(C)=O)CC1,,CN(C)C=O,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140155398A1,Cc1cc2ccnc(Cl)c2n1S(=O)(=O)c1ccccc1>>Cc1cc2ccnc(Cl)c2[nH]1,,CCO,,[Na+].[OH-],,test
US20150361065A1,COC(=O)/C=C/c1ccc(Oc2c(C=O)sc3cc(OC)ccc23)cc1.[C-]#[N+]C(C(C)C)S(=O)(=O)c1ccc(C)cc1>>COC(=O)/C=C/c1ccc(Oc2c(-c3ocnc3C(C)C)sc3cc(OC)ccc23)cc1,,CO,,C[O-].[Na+],,test
US20150232465A1,C[C@H]1CN(C(=O)c2ccccc2F)c2cc(Br)ccc2N1C(=O)C(F)(F)F>>C[C@H]1CN(C(=O)c2ccccc2F)c2cc(Br)ccc2N1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20140088078A1,COC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2CCC2CN(C(=O)OC(C)(C)C)C2)ccc2c1OCC1CC21.ClCCl>>CCN1CC(CCc2cc(F)ccc2S(=O)(=O)Nc2ccc3c(c2C(=O)OC)OCC2CC32)C1,,O=C(O)C(F)(F)F,,,,test
US20020019523A1,O=C(Cl)OCc1ccccc1.O=C(O)C1(C2CCCCC2)CCNCC1>>O=C(OCc1ccccc1)N1CCC(C(=O)O)(C2CCCCC2)CC1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20110245255A1,Cc1nc(N2CCN(C)CC2)c2nc(-c3ccccc3Cl)n([C@H](C)CO)c2n1.Cl>>Cc1nc(N2CCN(C)CC2)c2nc(-c3ccccc3Cl)n([C@H](C)CO)c2n1.Cl,,CCOCC,,C1COCCO1,,test
US20100063067A1,COC(=O)CP(=O)(OC)OC.COc1cc(N2CCC(=O)CC2)ccc1Cl>>COC(=O)C=C1CCN(c2ccc(Cl)c(OC)c2)CC1,,C1CCOC1,,[H-].[Na+],,test
US20090156578A1,CI.Cc1c(C(C)N[S@](=O)C(C)(C)C)sc2ccccc12>>Cc1c([C@@H](C)N(C)[S@](=O)C(C)(C)C)sc2ccccc12,,CN(C)C=O,,[H-].[Na+],,test
US06586633B1,CC(=O)c1cccc(CBr)c1.NC1CC1>>CC(=O)c1cccc(CNC2CC2)c1,,CO,,CCN(CC)CC,,test
US20080045550A1,CC(C)(C)OC(=O)N1CCC(N)CC1.Clc1ccc2c(Cl)ncnc2c1>>CC(C)(C)OC(=O)N1CCC(Nc2ncnc3cc(Cl)ccc23)CC1,,CN(C)C=O,,[H-].[Na+],,test
US04166125,O=C1c2ccccc2C(=O)N1c1ccccc1>>O=C1c2ccccc2CN1c1ccccc1,[Zn],CC(=O)O,,,,test
US20070259860A1,CC(=O)c1cccc(I)c1.CN(C)C=O.COC(=O)C(=O)OC>>COC(=O)c1cc(-c2cccc(I)c2)on1,,CCOC(C)=O,,Cl,[H-].[Na+],test
US05135562,C1CCNNC1.COC(=O)COC(=O)c1ccccc1C1(Cl)CC(F)=C(N=C=S)S1>>COC(=O)COC(=O)c1ccccc1C1(Cl)CC(F)=C(NC(=S)N2CCCCN2)S1,,Cc1ccccc1,,,,test
US20050043248A1,CCCCCC1CNC(C(=O)NC(C(C)C)C2OC(SC)C(O)C(O)C2O)C1.N#CCBr>>CCCCCC1CC(C(=O)NC(C(C)C)C2OC(SC)C(O)C(O)C2O)N(CC#N)C1,,CC#N,,CCN(CC)CC,,test
US20110200546A1,COC(=O)CC/C(C)=C/c1ccc(C)cc1>>C/C(=C\c1ccc(C)cc1)CCCO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100305067A1,COc1ccc(NC(C)=O)cc1Br>>COc1ccc(N)cc1Br,,CCO,,Cl,,test
US20130065861A1,CCCCCCCCNC(=O)OC[C@H](CSC[C@H](NC(=O)OCc1ccccc1)C(=O)NCCOCCOCCOCCP(=O)(OCC)OCC)OC(=O)NCCCCCCCC>>CCCCCCCCNC(=O)OC[C@H](CSC[C@H](N)C(=O)NCCOCCOCCOCCP(=O)(O)O)OC(=O)NCCCCCCCC,,ClCCl,,C[Si](C)(C)Br,,test
US20140343052A1,COc1ccc(B2OC(C)(C)C(C)(C)O2)c(C)c1C=O.Clc1ccnc(Cl)n1>>COc1ccc(-c2ccnc(Cl)n2)c(C)c1C=O,,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US04971963,CC(C)(C)OC(=O)CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(CO)CS[C@H]12)c1csc(N)n1.N#Cc1c(SCC(=N)N)nsc1S.[Na+]>>N#Cc1c(SCC(=N)N)nsc1SCC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)/C(=N\OCC(=O)O)c3csc(N)n3)[C@H]2SC1.[Na+],,CN(C)C=O,,,,test
US20100330199A1,CCCCOC(=O)c1nc(Br)c2snc(C)c2c1O.C[Sn](C)(C)C>>CCCCOC(=O)c1nc(C)c2snc(C)c2c1O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,,,test
US20140005168A1,CC(C)(C)OC(=O)N1CCN(c2cccc(-n3ncc4cnc(-c5cnccn5)cc43)n2)CC1>>c1cc(N2CCNCC2)nc(-n2ncc3cnc(-c4cnccn4)cc32)c1,,C1COCCO1,Cl,,,test
US03940419,N#CC1(N2C(=O)c3cccc(Cl)c3C2=O)CCCCC1.O=S(=O)(O)O>>NC(=O)C1(N2C(=O)c3cccc(Cl)c3C2=O)CCCCC1,,ClCCl,,,,test
US20080207654A1,CC(=O)c1cccc(CBr)c1.CCOC(=O)CC(C)=O>>CCOC(=O)C(Cc1cccc(C(C)=O)c1)C(C)=O,,C1CCOC1,,[Na],,test
US20130274243A1,CC(C)(C)OC(=O)N[C@@H](CC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O.N#Cc1ccc(-c2ccc(N)c(N)c2)cc1F>>CC(C)(C)OC(=O)N[C@@H](CC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)c1nc2cc(-c3ccc(C#N)c(F)c3)ccc2[nH]1,,CC#N,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20050131014A1,CCOC=C(C(=O)OCC)C(=O)c1ccccc1.Nc1ccccc1C(F)(F)F>>CCOC(=O)C(=CNc1ccccc1C(F)(F)F)C(=O)c1ccccc1,,Cc1ccccc1,,,,test
US05405861,CCOC(=O)C(=O)CBr.NC(=S)C1CC1>>CCOC(=O)c1csc(C2CC2)n1,,CCO,,,,test
USRE041149E1,CC(C)(C)OC(=O)NC(C#N)c1ccccc1.C[C@H](c1ccccc1)N1CC(N)C2(CCC2)C1>>C[C@H](c1ccccc1)N1CC(C(=O)OC(C)(C)C)C2(CCC2)C1,,C1CCOC1,,,,test
US20090306066A1,Cc1nc(NNC(=O)[C@H](CC2CCCC2)CN(C=O)OCc2ccccc2)c(F)c(N2CC(N(C)C)C(C)(C)C2)n1>>Cc1nc(NNC(=O)[C@H](CC2CCCC2)CN(O)C=O)c(F)c(N2CC(N(C)C)C(C)(C)C2)n1,[Pd],CO,,,,test
US20100075948A1,CC(C)(CO)CC#N.CI>>COCC(C)(C)CC#N,,CN(C)C=O,,O,[H-].[Na+],test
US20140243302A1,CC(=O)C12CCC(NC(=O)OC(C)(C)C)(CC1)CO2.COc1ccc2ncc(F)c(C[C@@H](O)C34CCC(NCc5ncc6c(n5)OCCO6)(CC3)CO4)c2n1>>COc1ccc2ncc(F)c(CC(C)(O)C34CCC(NC(=O)OC(C)(C)C)(CC3)CO4)c2n1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20090326006A1,COC(=O)c1cccc2[nH]c(N)nc12.Nc1cc2ccccc2cn1.O=C(n1ccnc1)n1ccnc1>>COC(=O)c1cccc2[nH]c(NC(=O)Nc3cc4ccccc4cn3)nc12,,CN(C)C=O,,O,,test
US20130190287A1,C1COCCO1.CC(C)Nc1nc(Cl)nc(Cl)n1.OB(O)c1cccc(F)c1>>CC(C)(O)CNc1nc(Cl)nc(-c2ccccc2F)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20040110754A1,CC(NC(=O)OC(C)(C)C)c1cccc(N2CCC(N(C)C)C2)c1>>CC(N)c1cccc(N2CCC(N(C)C)C2)c1,,CCOC(C)=O,,Cl,,test
US20150197530A1,CCOC(=O)Cc1ccsc1C(=O)c1ccc(-c2ccc(Cl)cc2)nc1>>O=C(O)Cc1ccsc1C(=O)c1ccc(-c2ccc(Cl)cc2)nc1,,CO,,[Na+].[OH-],,test
US07250523B2,C=CC(C)(C)CCc1ccccc1.O=[N+]([O-])O>>C=CC(C)(C)CCc1ccccc1[N+](=O)[O-],,CC(=O)OC(C)=O,,CC(=O)O,,test
US20110160251A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCC1CCC2(CC1)OCCO2>>Cc1ccc(S(=O)(=O)OCC2CCC3(CC2)OCCO3)cc1,,c1ccncc1,,O,,test
US20140005146A1,COC(=O)C(C)(C)C(C)NCc1ccccc1>>COC(=O)C(C)(C)C(C)N,[Pd],CO,,,,test
US04851422,O=C(OCc1ccc([N+](=O)[O-])cc1)C(=O)c1ccccc1C(=O)O.O=S(Cl)Cl>>O=C1OC(Cl)(C(=O)OCc2ccc([N+](=O)[O-])cc2)c2ccccc21,,CC(Cl)Cl,,,,test
US20090130076A1,CC(C)(C)OC(=O)Nc1nc2c(-c3cccc(Cl)c3)cc(Cc3ccc([N+](=O)[O-])cc3)cc2s1>>CC(C)(C)OC(=O)Nc1nc2c(-c3cccc(Cl)c3)cc(Cc3ccc(N)cc3)cc2s1,[Pd],CCOC(C)=O,,,,test
US20090209607A1,CCc1oc(C(=O)O)cc1-c1c(Cl)cnn1C.N[C@@H](Cc1ccccc1C(F)(F)F)CN1C(=O)c2ccccc2C1=O>>CCc1oc(C(=O)N[C@@H](Cc2ccccc2C(F)(F)F)CN2C(=O)c3ccccc3C2=O)cc1-c1c(Cl)cnn1C,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20130172384A1,CI.O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(Br)cc3F)n[nH]c2=O)C1>>Cn1nc(-c2ccc(Br)cc2F)n(C[C@@H]2CCN(C(=O)C3CC3)C2)c1=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US03978086,CC(C)Nc1cc2c(cc1C(=O)c1ccccc1)OCO2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)N(C(=O)C(F)(F)F)c1cc2c(cc1C(=O)c1ccccc1)OCO2,,Cc1ccccc1,,CCN(CC)CC,,test
US20150299194A1,CCOCc1nc2c(NC(c3ccccc3)(c3ccccc3)c3ccccc3)nc3cc(C(=O)OC)ccc3c2n1CC(C)(C)O>>CCOCc1nc2c(NC(c3ccccc3)(c3ccccc3)c3ccccc3)nc3cc(C(=O)O)ccc3c2n1CC(C)(C)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20130095193A1,CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)C(c2ccc(/C=N/O)cc2)C1.O=C1CCC(=O)N1Cl>>CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)C(c2ccc(/C(Cl)=N/O)cc2)C1,,CN(C)C=O,O,,,test
US20120264735A1,CCBr.CCOC(=O)Nc1cccc(Cc2nn(-c3cccc(O)c3)ccc2=O)c1>>CCOC(=O)Nc1cccc(Cc2nn(-c3cccc(OCC)c3)ccc2=O)c1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20080039462A1,C1=COCCC1.O=C(OCc1ccccc1)N1CCC(O)C1>>O=C(OCc1ccccc1)N1CCC(OC2CCCCO2)C1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20050113580A1,COC(=O)Cc1cccc(CCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(c2ccccc2)c2ccccc2)c1>>O=C(O)Cc1cccc(CCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(c2ccccc2)c2ccccc2)c1,,CO,O,Cl,[Na+].[OH-],test
US20060247210A1,COc1ccc(CN)cc1.Cc1n[nH]c(N)c1-c1nc2ccc(S(=O)(=O)Cl)cc2s1>>COc1ccc(CNS(=O)(=O)c2ccc3nc(-c4c(C)n[nH]c4N)sc3c2)cc1,,CO,,CN1CCOCC1,,test
US20030144320A1,O=C(O)CCOc1ccc(C(=O)O)cc1>>O=C(O)c1ccc2c(c1)C(=O)CCO2,,O=S(=O)(O)O,,,,test
US20090099200A1,CC(=O)OC(C)=O.NC(=NO)c1nnc(N2CCC(Oc3ccccc3Br)CC2)s1>>Cc1nc(-c2nnc(N3CCC(Oc4ccccc4Br)CC3)s2)no1,,c1ccncc1,,,,test
US20100204272A1,COC(=O)c1ccc(O)c([N+](=O)[O-])c1.N>>NC(=O)c1ccc(O)c([N+](=O)[O-])c1,,O,,Cl,,test
US05366991,CCc1nn(C)c(C(=O)Cl)c1Cl.ClCCl.FC(OC(F)(F)F)C(F)(F)ONCc1ccccc1>>CCc1nn(C)c(C(=O)NCc2ccc(OC(F)(F)C(F)OC(F)(F)F)c(Cl)c2)c1Cl,,ClCCl,,CCN(CC)CC,,test
US20130210796A1,CC1CNCC(C)N1.CS(=O)(=O)Cl>>CC1CN(S(C)(=O)=O)CC(C)N1,,ClCCl,,CCN(CC)CC,,test
US05576321,O=C(O)C(=O)O.c1cc(OC[C@@H]2CO2)c2cc[nH]c2c1.c1ccc2cc(C3CCNCC3)ccc2c1>>O=C(O)C(=O)O.O[C@H](COc1cccc2[nH]ccc12)CN1CCC(c2ccc3ccccc3c2)CC1,,CCOC(C)=O,,CO,,test
US20060063841A1,NOCc1ccc(Cl)c(Cl)c1.O=Cc1cc(Cl)ccc1NS(=O)(=O)C(F)(F)F>>O=S(=O)(Nc1ccc(Cl)cc1C=NOCc1ccc(Cl)c(Cl)c1)C(F)(F)F,,CCO,,Cl,CC(=O)[O-].[Na+],test
US04116674,CCN.Cc1nc(N[N+](=O)[O-])[nH]c(=O)c1CC(C)C>>CCNc1nc(C)c(CC(C)C)c(=O)[nH]1,,O,,CC(=O)O,,test
US20090143361A1,CC1=CC(C)(B(O)O)NO1.COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)cc(Cl)c4)n3c2n1>>COc1ccc2nc(C)c3c(C)nc(-c4c(C)noc4C)n3c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20100286181A1,COC(=O)c1cnc(Br)s1.Cc1[nH]c(C(=O)NC2CCNCC23OCCO3)c(Cl)c1Cl>>COC(=O)c1cnc(N2CCC(NC(=O)c3[nH]c(C)c(Cl)c3Cl)C3(C2)OCCO3)s1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,O,test
US04839377,COC(=O)Cl.N#CCc1c[nH]c2ccc(N)cc12>>COC(=O)Nc1ccc2[nH]cc(CC#N)c2c1,,CN(C)C=O,,,,test
US08969388B1,Cc1c(C(=O)O)c(=O)n(-c2ccccc2)n1C.ClCCl.Nc1ccc(O)cc1.On1nnc2cccnc21>>Cc1c(C(=O)Nc2ccc(Oc3ccnc(N)c3Cl)cc2)c(=O)n(-c2ccccc2)n1C,,CCOC(C)=O,O,CCN=C=NCCCN(C)C,,test
US20110269244A1,CC(C)Oc1c(OC(C)C)c(=O)c1=O.c1cc(-c2nc(N3CCOCC3)c3sc(CN4CCNCC4)cc3n2)c2cn[nH]c2c1>>CC(C)Oc1c(N2CCN(Cc3cc4nc(-c5cccc6[nH]ncc56)nc(N5CCOCC5)c4s3)CC2)c(=O)c1=O,,CC#N,,,,test
US20160168100A1,CCn1cc(C=O)cn1.O=C(O)CC(=O)O>>CCn1cc(/C=C/C(=O)O)cn1,,O,c1ccncc1,C1CCNCC1,Cl,test
US20100081690A1,NC(=O)[C@H]1CCCNC1.O=C(Cl)c1ccc(F)c(F)c1>>NC(=O)[C@H]1CCCN(C(=O)c2ccc(F)c(F)c2)C1,,ClCCl,,CCN(CC)CC,Cl,test
US20090197864A1,C[C@H](O)c1nnc2ccc(Cl)nn12.OB(O)c1ccccc1>>C[C@H](O)c1nnc2ccc(-c3ccccc3)nn12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20110136801A1,CC(C)(C)OC(=O)NCCCN.O=[N+]([O-])c1cnc2ccccc2c1O>>CC(C)(C)OC(=O)NCCCNc1c([N+](=O)[O-])cnc2ccccc12,,CCN(CC)CC,ClCCl,CN(C)C=O,O=S(Cl)Cl,test
US20160130482A1,CCCCCCC(C)O.CS(=O)(=O)O.Cc1ccccc1.O=C(O)CCC(=O)O>>CCCCCCC(C)OC(=O)CCC(=O)OC(C)CCCCCC,,Cc1ccccc1,,,,test
US20130188270A1,CCCCC(CC)CBr.c1ccc2c(c1)ccc1c3ccccc3[nH]c21>>CCCCC(CC)Cn1c2ccccc2c2ccc3ccccc3c21,,CN(C)C=O,,[H-].[Na+],,test
US20150031685A1,CCOC(=O)C(C)(C)S.O=[N+]([O-])c1cc(Br)ccc1F>>CCOC(=O)C(C)(C)Sc1ccc(Br)cc1[N+](=O)[O-],,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20090306369A1,BrBr.Cc1cccc(NC(=O)c2ccccc2C)c1>>Cc1cc(NC(=O)c2ccccc2C)ccc1Br,,CC(=O)O,,,,test
US20050032786A1,CN(CC(=O)OC(C)(C)C)c1cncc(-c2nc(=O)c3ccccc3s2)n1>>CN(CC(=O)O)c1cncc(-c2nc(=O)c3ccccc3s2)n1,,O=C(O)C(F)(F)F,,CC(C)OC(C)C,,test
US20140113882A1,CC(C)(C)OC(=O)N1CCN(c2nc(-c3ccnc4[nH]ccc34)nc3c(Cl)ncc(C4CC4)c23)CC1>>Clc1ncc(C2CC2)c2c(N3CCNCC3)nc(-c3ccnc4[nH]ccc34)nc12,,C1COCCO1,,Cl,,test
US20090209607A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1C(F)(F)F)C(=O)O>>CC(C)(C)OC(=O)N[C@H](CO)Cc1ccccc1C(F)(F)F,,C1CCOC1,,B,,test
US07214824B2,CC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(C)c1.CS(N)(=O)=O>>CC(=O)c1ccc(NS(C)(=O)=O)c(C)c1,,CCOC(C)=O,,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US20050038104A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Ic1c[nH]cn1>>CC(C)(C)OC(=O)n1cnc(I)c1,,C1CCOC1,CCOC(C)=O,O=C([O-])O.[Na+],,test
US05071841,Br.C=CC(=O)OC.Nc1ccc(C2CCCCC2)cc1>>COC(=O)C(Br)Cc1ccc(C2CCCCC2)cc1,,CC(C)=O,O,O=N[O-].[Na+],,test
US20130267546A1,Cc1nc2c(c(OS(=O)(=O)C(F)(F)F)c1C=O)CCN2C.OO>>Cc1nc2c(c(OS(=O)(=O)C(F)(F)F)c1OC=O)CCN2C,,ClCCl,,O=C([O-])O.[Na+],,test
US20050261291A1,ClCCNCCCl.Nc1ccccc1C1=CCCCCC1>>C1=C(c2ccccc2N2CCNCC2)CCCCC1,,Clc1ccccc1Cl,,Cl,,test
US04684398,CC(C)CN.CSC(=NC1CCCc2ccccc21)NC#N>>CC(C)CNC(=NC#N)NC1CCCc2ccccc21,,CC#N,,,,test
US20040192734A1,CCOC(=O)c1ccc(C#Cc2ccccc2F)o1>>O=C(O)c1ccc(C#Cc2ccccc2F)o1,,CCOC(C)=O,CO,C1CCOC1,[Na+].[OH-],test
US05514680,NCC(=O)O.O=[N+]([O-])c1cc(Cl)c(Br)cc1Cl>>O=C(O)CNc1cc(Br)c(Cl)cc1[N+](=O)[O-],,CN(C)C=O,O,O=C([O-])O.[Na+],,test
US20100121048A1,COC(=O)c1ncn(CC(O)c2ccccn2)c1-c1ccccc1>>O=C(O)c1ncn(CC(O)c2ccccn2)c1-c1ccccc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20050154042A1,COC(=O)CC1CC(CCc2c(-c3ccc(F)cc3)c(-c3ccccc3)c(C(N)=O)n2C(C)C)OC(C)(C)O1.COC(=O)c1ccc(I)nc1>>COC(=O)CC1CC(CCc2c(-c3ccc(F)cc3)c(-c3ccccc3)c(C(=O)Nc3ccc(C(=O)OC)cn3)n2C(C)C)OC(C)(C)O1,I[Cu]I,CCOC(C)=O,CN(C)C=O,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20030069233A1,COc1ccc([N+](=O)[O-])cc1Br.OB(O)c1ccncc1>>COc1ccc([N+](=O)[O-])cc1-c1ccncc1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US05045558,CCCC(c1ccc(C(=O)O)cc1)n1ccnc1.OC1CCCCC1>>CCCC(c1ccc(C(=O)OC2CCCCC2)cc1)n1ccnc1,,ClCCl,,Cl,c1ccncc1,test
US20080312226A1,N#C[S-].O=C(CBr)c1cccc(C(F)(F)F)c1>>N#CSCC(=O)c1cccc(C(F)(F)F)c1,,CCO,,O,,test
US20040209921A1,N#Cc1ncccc1N1CCCc2ccccc21>>NCc1ncccc1N1CCCc2ccccc21,[Ni],CO,,N,,test
US20070105904A1,C#Cc1cccnc1N.ON=C(Cl)Cc1ccc(CNc2ccccc2)cc1>>Nc1ncccc1-c1cc(Cc2ccc(CNc3ccccc3)cc2)no1,,O,,C1CCOC1,CCN(CC)CC,test
US04859684,CCOC(=O)c1cccc(N)c1N.CCOC(C)=N>>CCOC(=O)c1cccc2[nH]c(C)nc12,,CCO,,Cl,,test
US20040192688A1,ClCCCCOc1ccc2ccccc2c1.NCc1ccccc1>>c1ccc(CNCCCCOc2ccc3ccccc3c2)cc1,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130225620A1,N#CCC(=O)C1CC1(F)F.NN>>Nc1cc(C2CC2(F)F)[nH]n1,,CCO,,,,test
US20120142662A1,Cc1ccc(C=O)cc1C.N#CCc1cccc(F)c1>>Cc1ccc(/C=C(/C#N)c2cccc(F)c2)cc1C,,CCO,,C[O-].[Na+],,test
US20150018343A1,Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)OC(C)(C)C)C3.Cl>>Cc1nc2c3c(nn2c(C)c1Cl)CNC3.Cl,,CC(=O)O,,COC(C)(C)C,,test
US20160102105A1,O=C(Cl)C(=O)Cl.O=C(O)c1cnc(OCC(F)F)cn1>>O=C(Cl)c1cnc(OCC(F)F)cn1,,ClCCl,,CN(C)C=O,,test
US20120142668A1,CC[C@@H](/C=C/C(=O)N1CCc2ccccc21)NC(=O)[C@@H]1CCN1C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CC[C@@H](/C=C/C(=O)N1CCc2ccccc21)NC(=O)[C@@H]1CCN1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US03959322,C#CCCCc1cccc(OC)c1.C=O.CCNCC>>CCN(CC)CC#CCCCc1cccc(OC)c1,,C1COCCO1,CC(=O)O,O,,test
US20130059834A1,CC(=O)OC(C)=O.CC(C)CCON=O.Cc1ncccc1N>>CC(=O)n1ncc2ncccc21,,ClC(Cl)Cl,,CC(=O)[O-].[K+],,test
US20020091147A1,ClC1=NCCN1.Nc1ccc(CCC(=O)c2ccc(F)cc2)cc1>>O=C(CCc1ccc(NC2=NCCN2)cc1)c1ccc(F)cc1,,CC(C)O,CCOC(C)=O,O=S(=O)(O)O,,test
US04918213,CCCCC(CCOS(=O)(=O)c1ccc(C)cc1)C(F)(F)F.OCc1ccc(O)cc1>>CCCCC(CCOc1ccc(CO)cc1)C(F)(F)F,,CCO,,Cl,[Na+].[OH-],test
US20100087427A1,Brc1ccc(I)cc1.ClC(Cl)Cl.c1ccc(C[C@H]2CN(Cc3ccccc3)C[C@@H]2CNc2ccccc2)cc1>>Clc1ccc(N(C[C@H]2CN(Cc3ccccc3)C[C@@H]2Cc2ccccc2)c2ccccc2)cc1,[Cu],,,[I-].[K+],O=C([O-])O.[Na+],test
US20100286152A1,Cl.O=C(NNc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(c1cccnc1)N1CCN2CCC[C@@H]2C1>>Cl.O=C(NNc1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@@H](c1cccnc1)N1CCN2CCC[C@@H]2C1,,CO,,CCOCC,,test
US05250517,C=C[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(C)C.O=C(O)[C@H](Cc1ccccc1)NC(=O)N(Cc1ccccc1)Cc1ccccc1>>C=C[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)N(Cc1ccccc1)Cc1ccccc1)C(C)C,,CC#N,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US04946854,NC(=O)c1c(Cl)cccc1Cl.O=[N+]([O-])O>>NC(=O)c1c(Cl)ccc([N+](=O)[O-])c1Cl,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20100121052A1,Clc1ncc2cc(Br)ccc2n1.Cn1cc(-c2cc(N)cc(CO)c2)cn1>>Cn1cc(-c2cc(CO)cc(Nc3ncc4cc(Br)ccc4n3)c2)cn1,,CC(C)O,,,,test
US20030114668A1,CC(C)[C@H]1COCCN1.Cc1ccc(C[C@@H]2CN(CC=CCCl)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C>>Cc1ccc(C[C@@H]2CN(CC=CCN3CCOC[C@@H]3C(C)C)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C,,O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20020119973A1,CC(C)(C)OC(=O)N1CCC(=O)C1.Clc1ccc([Mg]Br)cc1>>CC(C)(C)OC(=O)N1CCC(O)(c2ccc(Cl)cc2)C1,,C1CCOC1,,,,test
US06239131B1,CCCN=C=O.COCN1C(=O)C(NO)CN(c2ccccc2)c2ccccc21>>CCCNC(=O)ON=C1CN(c2ccccc2)c2ccccc2N(COC)C1=O,,C1CCOC1,,CCN(CC)CC,,test
US20130137680A1,O=C(Nc1cccc(-c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)c1)c1ccc2nc3n(c2c1)CCCNC3=O>>O=C(Nc1cccc(-c2c[nH]cn2)c1)c1ccc2nc3n(c2c1)CCCNC3=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110263647A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(C(F)(F)F)nc1)CN(C(=O)OC(C)(C)C)c1ncc(-c2ccc3cnc(F)cc3c2)s1>>CC(C)(C)OC(=O)Nc1ncc(-c2ccc3cnc(F)cc3c2)s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,[Cl-].[Li+],,test
US04822775,N#CCCc1cccs1>>NCCCc1cccs1,,CCOCC,,O,[Na+].[OH-],test
US05476933,C=C(C)C(=C)C.CCOC(C)=O.CO.Cc1ccccc1.Oc1ccc(O)cc1>>COC1=CC(=O)C2CC(C)=C(C)CC2C1=O,,CO,,,,test
US20160002225A1,COc1ccc(Cn2nc(I)c3c(Cl)ccnc32)cc1.Oc1ccc(Cl)cc1>>COc1ccc(Cn2nc(I)c3c(Oc4ccc(Cl)cc4)ccnc32)cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US06384281B1,CN(C)C(=O)[C@@H]1[C@H]2CC[C@H](C2)[C@@H]1c1ccc2sccc2c1.O=S(=O)(c1ccccc1)N(F)S(=O)(=O)c1ccccc1>>CN(C)C(=O)[C@@H]1[C@H]2CC[C@H](C2)[C@@H]1c1ccc2sc(F)cc2c1,,C1CCOC1,,O,CC(C)[N-]C(C)C.[Li+],test
US04399296,C1CCOC1.CCOC(=N)C(O)c1cc(F)ccc1OC>>COc1ccc(F)cc1C1OC(=O)NC1=O,,Cc1ccccc1,,Cl,,test
US20090197871A1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cc(C)cc(C(=O)NCc2ccc(OC)c(Br)c2)c1.C[C@H]1CN(Cc2cccc(B3OC(C)(C)C(C)(C)O3)c2)CCN1C(=O)OC(C)(C)C>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cc(C)cc(C(=O)NCc2ccc(OC)c(-c3cccc(CN4CCN[C@@H](C)C4)c3)c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20060264429A1,CI.COC=Cc1cccc2c1OCC(=O)N2>>COC=Cc1cccc2c1OCC(=O)N2C,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20120041009A1,C=CC=O.O=c1nc(-c2ncnc(C(F)(F)F)c2Br)[nH]o1>>O=CCCn1c(-c2ncnc(C(F)(F)F)c2Br)noc1=O,,CCN(CC)CC,,CCO,,test
US06573279B1,C=O.COc1ccc(C(C)(C)CN)cc1OC>>COc1cc2c(cc1OC)C(C)(C)CNC2,,O=CO,,,,test
US20060094749A1,Cc1ncc(CNC(=O)c2ccc(C#N)cc2)c2c1OC(C)(C)OC2>>Cc1ncc(CNC(=O)c2ccc(C#N)cc2)c(CO)c1O,,O,,O=CO,,test
US06211184B1,CC#N.CN1CCOCC1.O=C(O)CN1CCCC(CCc2ccc3c(n2)NCCC3)C1=O>>CCO.CCOC(C)=O.N,,CC#N,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US20070003539A1,COC(=O)c1ccccc1C#N.Cl>>COC(=O)c1ccccc1CN.Cl,[Pd],CO,,C1COCCO1,,test
US20070032525A1,COC(=O)c1ccc2c(c1)nc(N(COCC[Si](C)(C)C)CC1CCN(Cc3cccc4ccccc34)CC1)n2COCC[Si](C)(C)C>>C[Si](C)(C)CCOCN(CC1CCN(Cc2cccc3ccccc23)CC1)c1nc2cc(CO)ccc2n1COCC[Si](C)(C)C,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110065930A1,CCOC(=O)C1=C(N[C@@H](C)c2ccccc2)CCCC1>>CCOC(=O)[C@@H]1CCCC[C@@H]1N[C@@H](C)c1ccccc1,,CC#N,,CC(=O)O,[BH4-].[Na+],test
US07060109B2,CCCCOC(=O)c1sc2ccc(OCC(=O)OCC)cc2c1OC(=O)C(C)(C)C>>O=C(O)COc1ccc2scc(O)c2c1,,CC(=O)O,,CCOC(C)=O,[Na+].[OH-],test
US20040167155A1,CCOC(=O)Oc1ccc(S(=O)(=O)N2c3ccccc3-c3ccc(F)cc3[C@@H]2C)cc1>>C[C@H]1c2cc(F)ccc2-c2ccccc2N1S(=O)(=O)c1ccc(O)cc1,,CO,,[Na+].[OH-],,test
US06080781,O=C1CCCc2cc(O)ccc21.O=Cc1ccc(F)cc1>>O=C1C(=Cc2ccc(F)cc2)CCc2cc(O)ccc21,,O,,CO,Cl,test
US07230020B2,COc1cccc(C(=O)Cl)c1.NCCc1cccs1>>COc1cccc(C(=O)NCCc2cccs2)c1,,C1CCOC1,,CCN(CC)CC,,test
US05409939,NN=Cc1ccc(CCCCC(=O)NC(CCS(=O)Cc2ccccc2)CC(=O)O)cc1.OO>>NN=Cc1ccc(CCCCC(=O)NC(CCS(=O)(=O)Cc2ccccc2)CC(=O)O)cc1,,CC(=O)O,,O,,test
US04758670,CC(C)(C)C1(C(F)n2cncn2)CO1.Oc1ccc(F)cc1>>CC(C)(C)C(O)(COc1ccc(F)cc1)C(F)n1cncn1,,COCCOCCOC,,[K],,test
US20020165234A1,CCOC(=O)COc1ccc(CC(C)(C)[N+](=O)[O-])cc1>>CCOC(=O)COc1ccc(CC(C)(C)N)cc1,O=[Pt],CCO,,[H][H],,test
US07713994B2,CC(=O)N1C(=O)Cc2ccccc2N1C(C)=O.COC(OC)OC>>CO/C=C1\C(=O)N(C(C)=O)N(C(C)=O)c2ccccc21,,CN(C)C=O,,CC(=O)OC(C)=O,,test
US04722929,CN(C)c1cc([N+](=O)[O-])ccc1C1=NC2=CCC(=O)NC2=N1.Cl>>CN(C)c1cc(N)ccc1C1=NC2=CCC(=O)NC2=N1.Cl,[Pd],CN(C)C=O,,O,[H][H],test
US20080070920A1,CCOP(=O)(CC#N)OCC.COc1ccc(COc2nc(OCc3ccc(OC)cc3)c(C(C)C)c(C(=O)c3cccc(C=O)c3)n2)cc1>>COc1ccc(COc2nc(OCc3ccc(OC)cc3)c(C(C)C)c(C(=O)c3cccc(C=CC#N)c3)n2)cc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20110206607A1,FCBr.Oc1ccc(F)cc1Cl>>FCOc1ccc(F)cc1Cl,,CCOCC,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20160221990A1,CC1(C)OB(c2ccncc2)OC1(C)C.O=Cc1cc(F)cc(Br)c1>>O=Cc1cc(F)cc(-c2ccncc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20050032786A1,CCSCc1cccc(-c2nc(=O)c3ccccc3s2)n1.O=C(OO)c1cccc(Cl)c1>>CCS(=O)Cc1cccc(-c2nc(=O)c3ccccc3s2)n1,,ClC(Cl)Cl,,,,test
US20120022060A1,CC(=O)OC(C)=O.Fc1ccc(Nc2ccnc3[nH]c4c(c23)CNCC4)cc1>>CC(=O)N1CCc2[nH]c3nccc(Nc4ccc(F)cc4)c3c2C1,,ClCCCl,,CCN(CC)CC,,test
US20050049252A1,CCOC(=O)C1=Cc2ccc(C(C)(C)C)cc2OC1C(F)(F)C(F)(F)F>>CC(C)(C)c1ccc2c(c1)OC(C(F)(F)C(F)(F)F)C(C(=O)O)=C2,,C1CCOC1,CCO,[Na+].[OH-],,test
US20080045530A1,CC(C)(C)OC(=O)N[C@H]1C[C@@H](O)C[C@H]1C(=O)O.CO>>COC(=O)[C@@H]1C[C@H](O)C[C@@H]1NC(=O)OC(C)(C)C,,CO,c1ccccc1,C[Si](C)(C)C=[N+]=[N-],,test
US04180662,COC(=O)c1cscc1NC(C)=O.O=S(=O)(Cl)Cl>>COC(=O)c1csc(Cl)c1NC(C)=O,,ClC(Cl)Cl,,,,test
US04088652,O=C(O)Cc1ccc(F)cc1.c1ccc(C23CNCC2C3)cc1>>O=C(Cc1ccc(F)cc1)N1CC2CC2(c2ccccc2)C1,,C1CCOC1,,O=C=O,,test
US20050267100A1,COc1ccc(N(C(=O)CBr)C(C)C)cn1.O=C1Cc2nnc(C3CCCCC3)n2-c2ccccc2N1>>COc1ccc(N(C(=O)CN2C(=O)Cc3nnc(C4CCCCC4)n3-c3ccccc32)C(C)C)cn1,,CN(C)C=O,O,[H-].[Na+],,test
US20160015656A2,O=C(NCCCCC(NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1)C(=O)[O-])OCc1ccccc1>>O=C(NCCCC[C@H](NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1)C(=O)O)OCc1ccccc1,,O,,CO,[K+].[OH-],test
US20160002215A1,CCOc1cc(-c2ccc(CC(=O)Nc3cc(-c4nn[nH]n4)cc(C(F)(F)F)c3)c(F)c2)cnc1OCc1ccc(OC)cc1>>CCOc1cc(-c2ccc(CC(=O)Nc3cc(-c4nn[nH]n4)cc(C(F)(F)F)c3)c(F)c2)c[nH]c1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040192701A1,COC(=O)c1cccc(-c2ccc(OC)c(OCc3ccccc3)c2)n1>>COC(=O)c1cccc(-c2ccc(OC)c(O)c2)n1,[Pd],C1CCOC1,CO,,,test
US20090042876A1,NCCc1c[nH]c2ccccc12.O=C(O)c1c[nH]c2c(=O)[nH]c3ccccc3c12>>O=C(NCCc1c[nH]c2ccccc12)c1c[nH]c2c(=O)[nH]c3ccccc3c12,,CCOCC,,,,test
US07786307B2,CC(C)[C@@H](COCc1ccccc1)C[C@H]1COC(C)(C)N1C(=O)OC(C)(C)C>>CC(C)[C@@H](CO)C[C@H]1COC(C)(C)N1C(=O)OC(C)(C)C,[Pd],C1CCOC1,,,,test
US05795901,CCI.[O-][N+]1(Cc2ccc(OCC3CC3)cc2)CCC(C(O)(c2ccc(C(F)(F)F)cc2)c2ccc(C(F)(F)F)cc2)CC1>>CCO[N+]1(Cc2ccc(OCC3CC3)cc2)CCC(C(O)(c2ccc(C(F)(F)F)cc2)c2ccc(C(F)(F)F)cc2)CC1.[I-],,CC#N,,,,test
US20110144105A1,CS(=O)(=O)c1ccc(B(O)O)cc1.Cc1ccc(S(=O)(=O)OC(=CC2CCCC2)c2cc3cc(NC(=O)OC(C)(C)C)cnc3n2S(=O)(=O)c2ccccc2)cc1>>CC(C)(C)OC(=O)Nc1cnc2c(c1)cc(C(=CC1CCCC1)c1ccc(S(C)(=O)=O)cc1)n2S(=O)(=O)c1ccccc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US20090069297A1,CCC(O)(CC(=O)c1cccc(Cl)c1)C(=O)O.NN>>CCc1cc(-c2cccc(Cl)c2)n[nH]c1=O,,CCCCO,,,,test
US04504568,[Ag].c1ccc2[nH]nnc2c1>>[Ag].c1ccc2[nH]nnc2c1,,O,,,,test
US20040152697A1,COC(=O)CN([C@H]1CCN([C@@H](C)C(=O)N2CCCCC2)C1=O)S(=O)(=O)c1ccc2cc(Cl)ccc2c1.Cl.O>>CO.C[C@@H](C(=O)N1CCCCC1)N1CC[C@H](N(CC(=O)O)S(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O.Cl,,C1CCOC1,O,[Li+].[OH-],,test
US20100324068A1,COC(=O)C1(c2cc(F)c(OC)c(F)c2)CC1>>COC(=O)C1(c2cc(F)c(O)c(F)c2)CC1,,ClCCl,,BrB(Br)Br,CO,test
US20090069305A1,CC(O)c1cc(-c2cc(Cl)ccn2)cs1>>CC(=O)c1cc(-c2cc(Cl)ccn2)cs1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US05166198,Clc1ncnc2c1ncn2OCc1ccccc1.N>>Nc1ncnc2c1ncn2OCc1ccccc1,,CCO,,[Br-].[K+],,test
US05110956,ClCc1ccncc1.SCCc1ccc2c(c1)OCO2>>c1cc(CSCCc2ccc3c(c2)OCO3)ccn1,,CCO,,Cl,[Na+].[OH-],test
US20010021718A1,CCCS(=O)(=O)C/C(N)=N/OC(=O)[C@H](CCCC1CCCCC1)CC(=O)OC(C)(C)C>>CCCS(=O)(=O)Cc1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1,,Cc1ccccc1C,,,,test
US20060205676A1,COc1ccc(COc2ccccc2-c2cc(C3=CCCN=C3C(C)(C)C)c(CO)c(N)n2)cc1.Cl>>Cl.Nc1nc(-c2ccccc2O)cc(C2=CCCNC2)c1CO,,C1COCCO1,,,,test
US20080200448A1,C=CCN(C(=O)C1CCN(c2[nH]c(=O)c(C(=O)OCC)cc2C#N)CC1)S(=O)(=O)Cc1ccccc1.CC(=O)OC(C)=O>>C=CCN(C(=O)C1CCN(c2nc(OC(C)=O)c(C(=O)OCC)cc2C#N)CC1)S(=O)(=O)Cc1ccccc1,c1ccncc1,,,,,test
US07071175B1,Cc1cc(C(C)(C)O[SiH2]C(C)(C)C)cnc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>Cc1cc(CO)cnc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04349684,COC(=O)CCCCCCCBr.O=c1[nH]cc(-c2ccc(Cl)cc2)n1-c1ccccc1>>COC(=O)CCCCCCCn1cc(-c2ccc(Cl)cc2)n(-c2ccccc2)c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20090131457A1,CO.COCCBr.Cn1nc(-c2cc(F)c(O)c(Br)c2)c2cnc(N)nc21>>CNc1ncc2c(-c3cc(F)c(OCCOC)c(Br)c3)n[nH]c2n1,,CN(C)C=O,CO,Cl,O=C([O-])[O-].[K+].[K+],test
US20080058384A1,CC1=C(C(=O)O)C(c2ccc(Cl)cc2)CC(=O)N1.CCOC(C)=O.CI>>COC(=O)C1=C(C)N(C)C(=O)CC1c1ccc(Cl)cc1,,CN(C)C=O,O,[H-].[Na+],,test
US20120149694A1,CCSCC1CC(c2ccc(C(F)(F)F)cc2)CN(C(=O)N2CCOCC2)C1.O=C(OO)c1cccc(Cl)c1>>CCS(=O)CC1CC(c2ccc(C(F)(F)F)cc2)CN(C(=O)N2CCOCC2)C1,,ClCCl,,,,test
US20090062333A1,CC(=O)OCC(=O)Cl.OCCNCC1CCCCC1>>CC(=O)OCC(=O)N(CCO)CC1CCCCC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160168097A1,CCN(C(=O)c1ccncc1)c1cccc(C(=O)OC)c1OC.Cl>>CCN(C(=O)c1ccncc1)c1cccc(C(=O)O)c1OC.Cl,,C1CCOC1,O,[Li+].[OH-],,test
US04973699,Nc1nc(C(=NOC2CC2)C(=O)N[C@@H]2C(=O)N3C(C(=O)[O-])=C(C[n+]4ccccc4)CS[C@H]23)cs1.O=S(=O)(O)O>>Nc1nc(C(=NOC2CC2)C(=O)N[C@@H]2C(=O)N3C(C(=O)O)=C(C[n+]4ccccc4)CS[C@H]23)cs1.O=S(=O)([O-])O,,O,,,,test
US04831265,CC(=O)OCC(=O)OOC(=O)COC(C)=O.COC1=C(OC)C(=O)C(C)=CC1=O>>COC1=C(OC)C(=O)C(COC(C)=O)=C(C)C1=O,,CC(=O)O,,,,test
US20110275608A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC1(O)CCN(Cc2ccccc2)CC1>>CC(C)(C)OC(=O)NCC1(O)CCN(Cc2ccccc2)CC1,,ClCCl,,,,test
US20070105890A1,COc1cc(C(=O)OC(C)(C)C)cc([N+](=O)[O-])c1>>COc1cc(N)cc(C(=O)OC(C)(C)C)c1,[Pd],C1CCOC1,,O,,test
US20120172599A1,CC1=C(C#N)C(=C(C#N)C#N)OC1(C)C.CCCCN(CCCC)c1ccc(C=Cc2cc(C)c(C=O)cc2C)c(OC)c1>>CCCCN(CCCC)c1ccc(C=Cc2cc(C)c(C=CC3=C(C#N)C(=C(C#N)C#N)OC3(C)C)cc2C)c(OC)c1,,C1CCOC1,CCO,C,O=C[O-].[NH4+],test
US20090324581A1,CC(C)(C)OC(=O)CCN(CC(=O)N1CCc2cc(OCc3ccc(C4CC4)c(OC(F)(F)F)c3)ccc21)C(=O)OC(C)(C)C>>O=C(O)CCNCC(=O)N1CCc2cc(OCc3ccc(C4CC4)c(OC(F)(F)F)c3)ccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US06677473B1,O=C(CBr)OCc1ccccc1.O=C(c1cc(I)c(O)c(I)c1)c1cc(I)c(O)c(I)c1>>O=C(COc1c(I)cc(C(=O)c2cc(I)c(O)c(I)c2)cc1I)OCc1ccccc1,,CC(=O)N(C)C,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20120040954A1,BrC(Br)(Br)Br.COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(OCCO)c(C)c3)nc2n1>>COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(OCCBr)c(C)c3)nc2n1,,CN(C)C=O,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04931083,CCOC(=O)C(C)Oc1ncn(-c2ccccc2)n1>>CC(Oc1ncn(-c2ccccc2)n1)C(=O)O,,CCO,,Cl,[K+].[OH-],test
US06617346B1,CCCOc1cc(O)ccc1Br.CI>>CCCOc1cc(OC)ccc1Br,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090227622A1,O=C1CCC(=O)N1I.c1ccc(-c2ccn3ccnc3c2)nc1>>Ic1cnc2cc(-c3ccccn3)ccn12,,CCO,CCOC(C)=O,,,test
US05610144,CCOC(=O)c1cccc(NC(=O)NCC(=O)N2[C@H](c3ccccc3)CC[C@@H]2c2ccccc2)c1>>O=C(NCC(=O)N1[C@H](c2ccccc2)CC[C@@H]1c1ccccc1)Nc1cccc(C(=O)O)c1,,CO,O,[K+].[OH-],,test
US20050234081A1,CCOP(=O)(COS(=O)(=O)C(F)(F)F)OCC.CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2ccc(N)cc2C)c1>>CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2ccc(NCP(=O)(O)O)cc2C)c1,,CC(=O)N(C)C,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130096160A1,Brc1csc(Br)n1.CCOC(=O)C1CCNCC1>>CCOC(=O)C1CCN(c2nc(Br)cs2)CC1,,C1COCCO1,,,,test
US04772703,COc1cccc(CCN)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1cccc(CCNS(=O)(=O)C(F)(F)F)c1,,ClCCl,,CCN(CC)CC,O,test
US20100197908A1,CC(O)c1ccccc1.Ic1ccc(I)nn1>>CC(Oc1ccc(I)nn1)c1ccccc1,,C1CCOC1,,O,[H-].[Na+],test
US20110166121A1,CC(C)(C)OC(=O)OC(=O)[O-].c1cc2c(cn1)NCCN2>>CC(C)(C)OC(=O)N1C=CC2=NCCNC2=C1,,ClCCl,,,,test
US06166006,Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(C(O)c4ccccn4)cc2)CCO3)cc1.O=C(OO)c1cccc(Cl)c1>>Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(C(O)c4cccc[n+]4[O-])cc2)CCO3)cc1,,C1CCOC1,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20100004208A1,CN.COc1cc(C(=O)c2c(Br)oc3c(OC(C)=O)c(OC)ccc23)cc(OC)c1OC>>CNc1oc2c(O)c(OC)ccc2c1C(=O)c1cc(OC)c(OC)c(OC)c1,,CC#N,,,,test
US20140296272A1,COC(=O)Cc1c(C)nc2sc3c(c2c1-c1ccc(C)cc1)CCCC3.FC(F)(F)CCI>>COC(=O)C(CCC(F)(F)F)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1)CCCC3,,CN(C)C=O,,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20060257987A1,CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)OC)c(C)c2)c(C(=O)c2ccccn2)c1>>CCc1ccc(O[C@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(C(=O)c2ccccn2)c1,,CO,O,Cl,[Na+].[OH-],test
US20110294854A1,O[C@@H]1CC[C@@H]2CN(c3cccc(C(F)(F)F)n3)C[C@H]12>>O=C1CC[C@@H]2CN(c3cccc(C(F)(F)F)n3)C[C@H]12,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20080227770A1,CCOC(=O)Cn1nc(C[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3N(CC(C)(C)COC(C)=O)C2=O)cc1O>>COc1cccc([C@H]2O[C@H](Cc3cc(O)n(CC(=O)O)n3)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC,,CCO,,Cl,[Na+].[OH-],test
US20150336925A1,COC(=O)COc1ccc(Cl)cc1C(C)=O>>Cc1c(C(=O)O)oc2ccc(Cl)cc12,,CCO,,C,C[O-].[Na+],test
US20140249134A1,Cc1cc(Cl)cc(Cl)n1.Cc1n[nH]c(C)n1>>Cc1cc(-n2nc(C)nc2C)cc(Cl)n1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130338137A1,NC(=O)c1nc(Cc2ccccc2F)c2ncccn12>>N#Cc1nc(Cc2ccccc2F)c2ncccn12,,O=P(Cl)(Cl)Cl,,,,test
US05552424,CC(C#Cc1cccc(C2CC(c3ccc(F)cc3)=NO2)c1)N(OC(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>CC(C#Cc1cccc(C2CC(c3ccc(F)cc3)=NO2)c1)NO,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080275032A1,CCOC(=O)c1c(O)c(-c2cccs2)nn(CCC(C)(C)C)c1=O.Nc1ccc([N+](=O)[O-])cc1S(N)(=O)=O>>CC(C)(C)CCn1nc(-c2cccs2)c(O)c(C2=NS(=O)(=O)c3cc([N+](=O)[O-])ccc3N2)c1=O,,c1ccncc1,,C1CCC2=NCCCN2CC1,,test
US20160068550A1,Nc1nccc(-c2ccccc2F)c1[N+](=O)[O-]>>Nc1nccc(-c2ccccc2F)c1N,[Pd],CO,,,,test
US20100160345A1,C=C(C[C@@H]1CCCCN1C(=O)OC(C)(C)C)OC.O=C1CCC(=O)N1Br>>COC(=O)C[C@@H]1CCCCN1C(=O)OC(C)(C)C,,C1CCOC1,,O,,test
US20110009619A1,COc1cc(/C=C/C(=O)O)cnc1-n1cnc(C)c1.NN1CCCN(c2ccccc2)C1=O>>COc1cc(/C=C/C(=O)NN2CCCN(c3ccccc3)C2=O)cnc1-n1cnc(C)c1,,CN(C)C=O,ClCCCl,CCN(C(C)C)C(C)C,On1nnc2ccccc21,test
US20140200231A1,O=C(Cl)CCl.c1ccc2c(c1)CC(Nc1ncc3c(n1)CCNC3)C2>>O=C(CCl)N1CCc2nc(NC3Cc4ccccc4C3)ncc2C1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US04287207,CN.O=C1N(c2ccccc2)C(=O)N1c1ccccc1>>CNC(=O)N(C(=O)Nc1ccccc1)c1ccccc1,,CC#N,,,,test
US20130115194A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COC(=O)N[C@H](C(=O)N1C[C@@H](C)C[C@H]1c1nc(-c2ccc(Br)cc2)c[nH]1)C(C)C>>COC(=O)N[C@H](C(=O)N1C[C@@H](C)C[C@H]1c1nc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)c[nH]1)C(C)C,,C1COCCO1,,ClCCl,CC(=O)[O-].[K+],test
US20100298325A1,CN(C)c1cccc(Oc2ccc(Cl)nc2)c1.NCc1ccccc1>>CN(C)c1cccc(Oc2ccc(NCc3ccccc3)nc2)c1,,C1COCCO1,CCOC(C)=O,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20150225373A1,C#CC(C)(C)c1cc(NC(=O)Oc2ccccc2)n(-c2ccc(C)cc2)n1.COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(N)c4ccccc34)n2)cc(OC)c1>>C#CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(OC)cc(OCCOCCOCCOC)c4)n3)c3ccccc23)n(-c2ccc(C)cc2)n1,,CC(=O)OC(C)C,,CCN(CC)CC,,test
US20070078184A1,C[C@H](NC(=O)C(F)(F)F)[C@H](O)c1ccc(OCc2ccccc2)c([N+](=O)[O-])c1>>C[C@H](NC(=O)C(F)(F)F)[C@H](O)c1ccc(OCc2ccccc2)c(N)c1,[Zn],CCO,O,[Cl-].[NH4+],,test
US20050239776A1,O=C(c1ncn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-c1cccnc1)c1c(CC2OCCO2)noc1-c1ccccc1Cl>>O=CCc1noc(-c2ccccc2Cl)c1C(=O)c1ncn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-c1cccnc1,,CC(=O)O,,O,,test
US20150045351A1,C=O.CC(C)(C)OC(=O)N1CCc2cccc3c2C(CN3)C1>>CN1CC2CN(C(=O)OC(C)(C)C)CCc3cccc1c32,,CC#N,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100249124A1,CCN1C(=O)COc2ccc(C(O)(C(C)c3ccc(-c4ccc(C(=O)OC)c(F)c4)cc3Cl)C(F)(F)F)cc21>>CCN1C(=O)COc2ccc(C(O)(C(C)c3ccc(-c4ccc(C(=O)O)c(F)c4)cc3Cl)C(F)(F)F)cc21,,CCCCCCC,,,,test
US20090198063A1,CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)C1CCN(CCn2c(=O)ccc3ncc(F)cc32)CC1.Cl>>Cl.O=c1ccc2ncc(F)cc2n1CCN1CCC(NCc2cc3c(cn2)OCCO3)CC1,,CCO,,,,test
US20020165259A1,CC(=O)Nc1ncc(/C=C/c2ncc(C(C)(C)C)o2)s1>>CC(=O)Nc1ncc(CCc2ncc(C(C)(C)C)o2)s1,[Pd],CCOC(C)=O,,[H][H],,test
US04837235,CCn1cc(Cc2ccc(C(=O)OC)cc2OC)c2cc([N+](=O)[O-])ccc21>>CCn1cc(Cc2ccc(C(=O)OC)cc2OC)c2cc(N)ccc21,[Pd],C1CCOC1,,,,test
US20070244159A1,CC(C)(CO)c1cc2cc(N)ccc2[nH]1.O=C(O)C1(c2ccc3c(c2)OCO3)CC1>>CC(C)(CO)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc2[nH]1,,CC#N,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100197683A1,CC1(C)CO1.CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(-c2ccc(O)cc2)c2ncnn12>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(-c2ccc(OCC(C)(C)O)cc2)c2ncnn12,,CN(C)C=O,,Cl,[H-].[Na+],test
US20080064715A1,CC(C)(C)OC(=O)NCCON=C(c1ccccc1)c1c[nH]c2cnccc12>>NCCON=C(c1ccccc1)c1c[nH]c2cnccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040077726A1,NO.O=C(Cl)C=Cc1cccc(S(=O)(=O)Nc2cccc3ccccc23)c1>>O=C(C=Cc1cccc(S(=O)(=O)Nc2cccc3ccccc23)c1)NO,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US06172228B2,Clc1ccc(C(c2ccccc2)N2CCNCC2)cc1.O=S(=O)(CCCCCCl)NCCO>>O=S(=O)(CCCCCN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1)NCCO,,CCN(C(C)C)C(C)C,,,,test
US20140221344A1,Cc1ccc(Cl)nn1.O=C(NC1CC1)c1ccc(F)c(B(O)O)c1>>Cc1ccc(-c2cc(C(=O)NC3CC3)ccc2F)nn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20050009804A1,COC(=O)c1sc(-c2cccc(F)c2)cc1N(C(=O)C1CCC(C)CC1)C(C)C>>CC1CCC(C(=O)N(c2cc(-c3cccc(F)c3)sc2C(=O)O)C(C)C)CC1,,C1COCCO1,,O,[Li+].[OH-],test
US20090221663A1,CCCSc1c(C(=O)N2CCC(c3ccccc3C(F)(F)F)C2)cnn1-c1ccc(C(=O)OC)cc1>>CCCSc1c(C(=O)N2CCC(c3ccccc3C(F)(F)F)C2)cnn1-c1ccc(C(=O)O)cc1,,CO,,[Na+].[OH-],,test
US20100004239A1,CCOC(=O)CC(=O)CCNC(=O)OC(C)(C)C.NCC(=O)c1ccccc1>>CCOC(=O)c1c(-c2ccccc2)c[nH]c1CCNC(=O)OC(C)(C)C,,CCO,O,CC(=O)[O-].[Na+],,test
US20060084673A1,O=C1CN(C(=O)OCc2ccccc2)C(NCc2ccc(F)cc2Cl)=N1.O=Cc1ccc2ncccc2n1>>O=C1N=C(NCc2ccc(F)cc2Cl)NC1=Cc1ccc2ncccc2n1,,CC(C)O,,C1CCNCC1,,test
US20110015157A1,C=CC(C)=O.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@H](N)c1ccccc1>>CC(=O)CCN(C(=O)OC(C)(C)C)[C@@H](C)c1ccccc1,,C1CCOC1,,,,test
US20130216498A1,CC(C)(C)OC(=O)N1CCC[C@@H](Nc2cc(Cl)nc(-c3cnc4ccc(F)cn34)n2)C1.c1nc[nH]n1>>CC(C)(C)OC(=O)N1CCC[C@@H](Nc2cc(-n3cncn3)nc(-c3cnc4ccc(F)cn34)n2)C1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090312383A1,COc1ccc(C(=O)c2cccc3[nH]c(=O)n(C)c23)cc1.O=P(Cl)(Cl)Cl>>COc1ccc(C(=O)c2cccc3nc(Cl)n(C)c23)cc1,,CCOC(C)=O,,,,test
US20120129811A1,CN.COc1ccc(S(=O)(=O)Cl)cc1[N+](=O)[O-]>>CNS(=O)(=O)c1ccc(OC)c([N+](=O)[O-])c1,,C1CCOC1,,,,test
US20090076062A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COCCCOc1cc(C[C@@H](C[C@H](N)[C@@H]2C[C@@H](C(C)C)C(=O)O2)C(C)C)cc(OC)c1>>COCCCOc1cc(C[C@@H](C[C@H](NC(=O)OC(C)(C)C)[C@@H]2C[C@@H](C(C)C)C(=O)O2)C(C)C)cc(OC)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100081680A1,COC(=O)C1C(=O)C(C(=O)OC)C2CC(c3cccc(Br)c3)CC1N2>>O=C1CC2CC(c3cccc(Br)c3)CC(C1)N2,,CS(C)=O,O,[Cl-].[Na+],,test
US04894386,CCCNC(=O)/C=C/c1ccc2cc[nH]c2c1.COC(=O)c1ccc(CBr)c(OC)c1>>CCCNC(=O)/C=C/c1ccc2ccn(Cc3ccc(C(=O)OC)cc3OC)c2c1,,CN(C)C=O,,[H-].[Na+],,test
US07179823B1,CCOC(=O)CCc1c[nH]nc1OCC.Cc1oc(-c2ccco2)nc1COc1cc(CCl)ccn1>>CCOC(=O)CCc1cn(Cc2ccnc(OCc3nc(-c4ccco4)oc3C)c2)nc1OCC,,CN(C)C=O,,O,[H-].[Na+],test
US20020173664A1,CCCCCCCCCC(=O)N1C(=O)OC(=O)[C@@H]1C.COC(=O)[C@@H](N)Cc1ccccc1>>CCCCCCCCCC(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC,,C1CCOC1,,CN1CCOCC1,Cl,test
US03941821,CCOC(=O)C(O)c1ccc(-c2ccccc2Br)cc1.FC(F)(F)I>>CCOC(=O)C(O)c1ccc(-c2ccccc2C(F)(F)F)cc1,[Cu],CN(C)C=O,,,,test
US20140375943A1,O=C(OCCOCc1ccccc1)c1cc(-c2ccc(OCCOCc3ccccc3)cc2)cc(-c2ccc(OCc3ccccc3)cc2)c1>>O=C(OCCO)c1cc(-c2ccc(O)cc2)cc(-c2ccc(OCCO)cc2)c1,[Pd],C1CCOC1,,C,,test
US20050096380A1,CC(C)Oc1cc2c(cc1Br)C(=O)CC(C)(C)O2.O=S(=O)(Cl)Cl>>CC(C)Oc1c(Br)cc2c(c1Cl)OC(C)(C)CC2=O,,ClCCl,,,,test
US20080280871A1,CCc1cnc(CCN)o1.Cc1nc(NC(=O)n2ccnc2)sc1-c1ccc(S(C)(=O)=O)c(C#N)c1>>CCc1cnc(CCNC(=O)Nc2nc(C)c(-c3ccc(S(C)(=O)=O)c(C#N)c3)s2)o1,,CN(C)C=O,,CCN(CC)CC,,test
US20100029611A1,C[C@H](N[S@](=O)C(C)(C)C)c1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1>>C[C@H](N)c1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1,,CO,,C1COCCO1,Cl,test
US20110256128A1,CC(=O)O[C@@H](C)C(=O)N(C[C@@H]1CN(C(=O)OCc2ccccc2)C[C@@H]1F)[C@@H](c1nc(-c2cc(F)ccc2F)nn1Cc1cccc(F)c1)C(C)(C)C>>C[C@H](O)C(=O)N(C[C@@H]1CNC[C@@H]1F)[C@@H](c1nc(-c2cc(F)ccc2F)nn1Cc1cccc(F)c1)C(C)(C)C,[Pd],CCOC(C)=O,CO,O=C([O-])[O-].[K+].[K+],,test
US04868321,C[Si](C)(C)N=[N+]=[N-].O=C=Nc1ccc(Cl)cc1F>>O=c1[nH]nnn1-c1ccc(Cl)cc1F,,O,,Cc1ccccc1,,test
US20120010190A1,C=CCC(CC(=O)c1ccc(OC)nc1)c1ccc(Br)cc1>>C=CCC(CC(=O)c1ccc(=O)[nH]c1)c1ccc(Br)cc1,,C1COCCO1,,Cl,,test
US04962102,Nc1cccc(Br)c1.O=[N+]([O-])c1sc(Cl)nc1Cl>>O=[N+]([O-])c1sc(Nc2cccc(Br)c2)nc1Cl,,CN(C)C=O,,,,test
US05004751,BrCc1ccccc1.Sc1nc2ccccc2s1>>c1ccc(CSc2nc3ccccc3s2)cc1,,CN(C)C=O,,CCN(CC)CC,O,test
US05981572,O=C1NC(=O)c2ccccc21.OCCCc1ccc(Cl)c2occc12>>O=C1c2ccccc2C(=O)N1CCCc1ccc(Cl)c2occc12,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040106622A1,CCOC(=O)C1CCN(c2cc([N+](=O)[O-])ccc2OC)CC1>>COc1ccc([N+](=O)[O-])cc1N1CCC(C(=O)O)CC1,,CO,,[Na+].[OH-],,test
US20090239848A1,Nc1cnn(-c2ccccc2)c1.O=C(O)CC(=O)N1CCN(C(=O)c2ccccc2Br)CC1>>O=C(CC(=O)N1CCN(C(=O)c2ccccc2Br)CC1)Nc1cnn(-c2ccccc2)c1,CN(C)c1ccncc1,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20050137241A1,Br.O=C1CC(C=C(F)F)CN1>>O=C1CC(CC(F)(F)Br)CN1,,O,,,,test
US20090306082A1,CCOC(=O)Cl.COc1cccc2cc(CCN)oc12>>CCOC(=O)NCCc1cc2cccc(OC)c2o1,,C1CCOC1,,CCN(CC)CC,,test
US20100267712A1,C=O.COc1ccc2c(c1)C(=O)N(c1ccc3c(c1)NCCN3)C2.[BH3-]C#N>>COc1ccc2c(c1)C(=O)N(c1ccc3c(c1)N(C)CCN3C)C2,,CC(=O)O,,[Na+].[OH-],,test
US20140187542A1,CC(C)(C)OC(=O)N[C@H]1CNC(=O)C1.COCN1C(=O)COc2ccc(Br)cc21>>COCN1C(=O)COc2ccc(N3C[C@H](NC(=O)OC(C)(C)C)CC3=O)cc21,[Cu]I,Cc1ccccc1,ClCCl,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US06043368,C1CSCSC1.Cl.Clc1ccccc1CNCCc1cccs1>>Cl.Clc1ccccc1CN1CCc2sccc2C1,,COCCOC,,Cl,,test
US20150031727A1,O=C(OCc1ccccc1)c1ccc(CBr)s1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>O=C(OCc1ccccc1)c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)s1.[Br-],,Cc1ccccc1,,,,test
US20070281943A1,Brc1cn[nH]c1C1CC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(c2cn[nH]c2C2CC2)OC1(C)C,,CS(C)=O,,CC(=O)[O-].[K+],,test
US20160257652A1,CCOC(=O)[C@H]1[C@@H]2Cc3cc(OCc4cc(-c5ccc(O)cc5F)c(C(F)(F)F)cc4F)ncc3[C@H]12.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)[C@H]1[C@@H]2Cc3cc(OCc4cc(-c5ccc(OS(=O)(=O)C(F)(F)F)cc5F)c(C(F)(F)F)cc4F)ncc3[C@H]12,,ClCCl,,CCN(CC)CC,O,test
US20130210785A1,CC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C.CON>>CO/N=C(\C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,,O,,Cl,c1ccncc1,test
US05356893,C1COCCN1.Cc1cc(C(=O)O)ccc1Br>>Cc1cc(C(=O)N2CCOCC2)ccc1Br,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20080171772A1,C1=COCC1.CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(O)cc2n1Cc1ccccc1>>CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(OC3CCCO3)cc2n1Cc1ccccc1,,ClCCl,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20130210880A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc2c(c1)CNC2=O>>COc1ccc2c(c1)CN(C(=O)OC(C)(C)C)C2=O,CN(C)c1ccncc1,O,,CCN(CC)CC,ClCCl,test
US20060079533A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCC1CNCCC1c1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCC(c2ccc(F)cc2)C(CO)C1,,C1COCCO1,,O,O=C([O-])O.[Na+],test
US20050101614A1,CN.COC(=O)c1c2cccc(-c3ccc(Cl)cc3Cl)c2nn1C>>CNC(=O)c1c2cccc(-c3ccc(Cl)cc3Cl)c2nn1C,,CO,,,,test
US06136823,NCC(O)C(F)(F)F.Nc1cc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Cl)c32)c(F)cc1F>>Nc1cc(-n2cc(C(=O)O)c(=O)c3cc(F)c(NCC(O)C(F)(F)F)c(Cl)c32)c(F)cc1F,,c1ccncc1,,CCN(CC)CC,,test
US20150250894A1,CCNCCN.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCNCCNC(c1ccccc1)(c1ccccc1)c1ccccc1,,CCOC(C)=O,CO,,,test
US20140005213A1,CO[C@@H](C)COS(=O)(=O)c1ccc(C)cc1.Cc1ccc2cc(F)c(O)cc2n1>>CO[C@@H](C)COc1cc2nc(C)ccc2cc1F,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060052371A1,COC(=O)c1ccc(C#N)cc1NC(=O)C(F)(F)F>>COC(=O)c1ccc(C#N)cc1N,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20090227555A2,C1CNCCNC1.CCN(C(C)C)C(C)C.CCOC(=O)c1cnc(Cl)c(C#N)c1>>CCOC(=O)c1c(C)ncc(C#N)c1N1CCCNCC1,,ClCCl,,,,test
US20150152102A1,CCOC(=O)CC(=O)C(F)(F)F.Nc1cc(C2CCN(c3ccc(Cl)cn3)CC2)n[nH]1>>O=C1CC(O)(C(F)(F)F)c2c(C3CCN(c4ccc(Cl)cn4)CC3)n[nH]c2N1,,CC(=O)O,,O=C([O-])O.[Na+],,test
US20100144770A1,CC(=O)c1ccccc1OCC(C)C.N#Cc1cc(C(=O)Cl)ccc1F>>CC(C)COc1ccccc1C(=O)CC(=O)c1ccc(F)c(C#N)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20040209921A1,Cc1cnc(C=O)c(C)c1.NCCCCS(=O)(=O)c1nc2ccccc2[nH]1>>Cc1cnc(CNCCCCS(=O)(=O)c2nc3ccccc3[nH]2)c(C)c1,,CO,ClCCl,[BH4-].[Na+],,test
US20100099681A1,CC1(C)C(=O)N(Br)C(=O)N1Br.COC(=O)c1ccccc1Nc1cc(C)nn1-c1ccc(F)cc1C>>COC(=O)c1ccccc1Nc1c(Br)c(C)nn1-c1ccc(F)cc1C,,ClCCl,,,,test
US06884868B1,CC(C)(C)OC(=O)N1CCC(OCCCO)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(OCCCOS(C)(=O)=O)CC1,,CCOC(C)=O,,CCN(CC)CC,O,test
US05432177,CC(C)(C)OC(=O)N1CCN(c2ccc(O)cc2)CC1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCN(c2ccc(OS(=O)(=O)C(F)(F)F)cc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20090197863A1,NC(=O)c1cccc2nc(C3CCCN(C(=O)OCc4ccccc4)C3)oc12>>NC(=O)c1cccc2nc(C3CCCNC3)oc12,[Pd],CO,,[H][H],,test
US20010041709A1,BrP(Br)Br.OC/C=C/C#Cc1ccccc1>>BrC/C=C/C#Cc1ccccc1,,CCOC(C)=O,Cc1ccccc1,,,test
US06630488B1,CC(C)(C)OC(=O)NCCCCOc1ccn2c(=O)cc(C(=O)NC[C@H](NS(=O)(=O)c3ccccc3)C(=O)OC(C)(C)C)cc2c1.NCCCOc1ccn2c(=O)cc(C(=O)NC[C@H](NS(=O)(=O)c3ccccc3)C(=O)O)cc2c1.O=C(O)C(F)(F)F>>NCCCCOc1ccn2c(=O)cc(C(=O)NC[C@H](NS(=O)(=O)c3ccccc3)C(=O)O)cc2c1.O=C(O)C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150274777A1,COC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>COC(=O)[C@@H](N)Cc1ccc(OC)cc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US05530015,BrCc1ccccc1.CC(C)c1cc(Br)ccc1O>>CC(C)c1cc(Br)ccc1OCc1ccccc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US03953506,CCN=C=O.NC1CCCc2ccccc21>>CCNC(=O)NC1CCCc2ccccc21,,CCOCC,,,,test
US20080039459A1,CN1CCNCC1.CS(=O)(=O)OCC#Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1>>CN1CCN(CC#Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1,,ClCCl,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20050090533A1,CN(C(=O)C(C)(C)c1cc(Cl)cc(Cl)c1)c1cnc(Cl)cc1-c1ccccc1Cl.OC[C@@H]1C[C@@H](O)CN1>>CN(C(=O)C(C)(C)c1cc(Cl)cc(Cl)c1)c1cnc(N2C[C@H](O)C[C@H]2CO)cc1-c1ccccc1Cl,,O=C([O-])O,[Na+],CS(C)=O,,test
US20120035408A1,CS(=O)(=O)c1ccc(B(O)O)cc1.Nc1nccnc1Br>>CS(=O)(=O)c1ccc(-c2cnc(N)cn2)cc1,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,CC#N,,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20070197526A1,CCOC(=O)C(=O)CC(C)=O.COc1ccc(NN)cc1>>CCOC(=O)c1cc(C)nn1-c1ccc(OC)cc1,,CCO,O,Cl,,test
US20030064991A1,Cc1c(C(=O)OCc2ccccc2)c2cc(-c3cccnc3)ccc2n1C(=O)OC(C)(C)C>>Cc1[nH]c2ccc(-c3cccnc3)cc2c1C(=O)OCc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080153852A1,Nc1nc(Cl)cc(Cl)n1.OC(c1ccccc1-n1ccnc1)C(F)(F)F>>Nc1nc(Cl)cc(OC(c2ccccc2-n2ccnc2)C(F)(F)F)n1,,C1CCOC1,,[H-].[Na+],,test
US04555518,CCO.O=[N+]([O-])c1ccc(OC(F)(F)C(F)F)cc1>>CC(=O)Nc1ccc(OC(F)(F)C(F)F)cc1,[Pd],,,,,test
US20080153812A1,COC(=O)c1ccc(N2CCN(C(C)=O)CC2)cc1.COc1cc(CCc2cc(N)n(C(=O)OC(C)(C)C)n2)cc(OC)c1>>COc1cc(CCc2cc(NC(=O)c3ccc(N4CCN(C(C)=O)CC4)cc3)n[nH]2)cc(OC)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20100063108A1,CC(C)Cc1cc(C(=O)OC(C)(C)C)cc(Cl)n1.Cl>>CC(C)Cc1cc(C(=O)O)cc(Cl)n1.Cl,,C1COCCO1,Cl,,,test
US20020035263A1,COc1ccc(F)cc1C1(O)CCN(Cc2ccccc2)CC1>>COc1ccc(F)cc1C1(O)CCNCC1,,CO,,,,test
US20040029902A1,CC(C)(C)OC(=O)N1CCc2ccc(Nc3nc(Cl)ncc3F)cc2C1>>Fc1cnc(Cl)nc1Nc1ccc2c(c1)CNCC2,,ClCCl,O=C(O)C(F)(F)F,,,test
US20130190248A1,CC(C)(C)OC(=O)N[C@@H](CN)C(=O)O.NCCn1ccnc1.O=C(O)C(F)(F)F>>NCCn1ccnc1.NC[C@H](N)C(=O)O.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20100009991A1,CC(C)(C)OC(=O)n1ccc2c(/C=C/CCl)cccc21.O=c1ccc(C(c2ccccc2)c2ccccc2)c[nH]1>>CC(C)(C)OC(=O)n1ccc2c(/C=C/Cn3cc(C(c4ccccc4)c4ccccc4)ccc3=O)cccc21,,CN(C)C=O,,,,test
US20070028805A1,CCOP(=O)(CCCN)OCC>>CCOP(=O)(CCC#N)OCC,,CCO,,NN,O,test
US20130196962A1,CC(=O)OCC(=O)[C@@]1(C)[C@H](C)CC2C3CCC4=CC(=O)CC[C@]4(C)C3=CC[C@@]21C>>C[C@@H]1CC2C3CCC4=CC(=O)CC[C@]4(C)C3=CC[C@]2(C)[C@@]1(C)C(=O)CO,,CO,,C[O-].[Na+],,test
US04271163,Nc1ccc(C2=NNC(=O)C3CC23)cc1.O=CO>>O=CNc1ccc(C2=NNC(=O)C3CC23)cc1,,O,,,,test
US05733918,O=C1c2ccccc2-c2c1[nH]c(=O)c1ccccc21.O=P(Cl)(Cl)Cl>>O=C1c2ccccc2-c2c1nc(Cl)c1ccccc21,,CN(C)C=O,,,,test
US20090221645A1,CC(Br)C(=O)c1ccc(F)c2ccccc12.S=C1NCCN1>>Br.CC1=C(c2ccc(F)c3ccccc23)N2CCN=C2S1,,CC(=O)O,,CCO,,test
US20020038025A1,CN(C(=O)OC(C)(C)C)c1ccc(C#CCCCOS(C)(=O)=O)cc1.CNC>>CN(C)CCCC#Cc1ccc(N(C)C(=O)OC(C)(C)C)cc1,,CC(=O)N(C)C,,,,test
US05821251,COc1ccc(CC2CCC3=C(C2)CC(CO)C(=O)N3)cc1>>COc1ccc(CC2CCC3NCC(CO)CC3C2)cc1,,C1CCOC1,,CC(=O)O,Cl,test
US20160184285A1,CNc1ccc(OC)cc1.COc1cccc(C(=O)C2CCNCC2)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc(CNC(=O)N2CCC(C(=O)c3cccc(OC)c3)CC2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US06518268B1,Nc1cccc(C=C2SC(=O)NC2=O)c1.O=C1OC(=O)c2cc(Cl)c(Cl)cc21>>O=C1NC(=O)C(=Cc2cccc(NC(=O)c3cc(Cl)c(Cl)cc3C(=O)O)c2)S1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20080039444A1,COc1ccc(CCCCN2CCC[C@H]2Cn2nc(Cc3ccc(Cl)cc3)c3ccccc3c2=O)cc1>>O=c1c2ccccc2c(Cc2ccc(Cl)cc2)nn1C[C@@H]1CCCN1CCCCc1ccc(O)cc1,,ClCCl,,BrB(Br)Br,,test
US20160168101A1,C#CCN.O=C=Nc1cccc(C(F)(F)F)c1>>C#CCNC(=O)Nc1cccc(C(F)(F)F)c1,,CC#N,,,,test
US20070281918A1,C=CCOc1nc2c(cc1I)C(C)CN(C(=O)C(F)(F)F)CC2>>Cc1coc2nc3c(cc12)C(C)CN(C(=O)C(F)(F)F)CC3,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC(=O)N(C)C,,CC(=O)[O-].[Na+],,test
US20080214859A1,COC(=O)CC1CCC(=O)C1CC(OC)OC>>COC(=O)CC1CCC(=O)C1CC=O,,O,,CC(=O)O,,test
US20030232416A1,C/C(=C\c1csc(C)n1)[C@@H]1CC=CCCC[C@H](C)[C@H](O)[C@@H](C)C(=O)C(C)(C)[C@@H](O)CC(=O)O1.CC1(C)OO1>>C/C(=C\c1csc(C)n1)[C@@H]1C[C@@H]2O[C@@H]2CCC[C@H](C)[C@H](O)[C@@H](C)C(=O)C(C)(C)[C@@H](O)CC(=O)O1,,ClCCl,,,,test
US20130064770A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCCOc1ccccc1N1CCN(Cc2nc3ccccc3s2)CC1>>Cc1ccc(S(=O)(=O)OCCOc2ccccc2N2CCN(Cc3nc4ccccc4s3)CC2)cc1,,ClCCl,,CCN(CC)CC,,test
US05342546,Brc1ccc(Br)cc1.CCCCCC1C=CC(=O)CC1>>CCCCCC1=CCC(O)(c2ccc(Br)cc2)CC1,,CCOCC,,Cl,[Mg],test
US20100234472A1,CC(=O)Nc1ccc(O)cc1.CC(Br)CCBr>>CC(=O)Nc1ccc(OCCCCBr)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140235660A1,COc1ccc(-c2sc3cc(OC)ccc3c2Oc2ccc(/C=C/C(=O)O)cc2)cc1.NCCC(F)(F)F>>COc1ccc(-c2sc3cc(OC)ccc3c2Oc2ccc(/C=C/C(=O)NCCC(F)(F)F)cc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100280043A1,CC(C)(C)OC(=O)N1CCN(c2c(C3CC3)cnc3[nH]nc(I)c23)CC1.Cl>>Cl.Ic1n[nH]c2ncc(C3CC3)c(N3CCNCC3)c12,,C1COCCO1,,,,test
US20140099333A1,CC1(C)OC(=O)CC(=O)O1.O=Cc1cc(F)c(Br)cc1F>>O=C(O)C=Cc1cc(F)c(Br)cc1F,,CCN(CC)CC,,Cl,,test
US20110230459A1,O=C(CN1CCCC(c2ccc(F)cc2)(c2ccc(F)cc2)C1=O)N1CCN(C(=O)OCc2ccccc2)CC1>>O=C(CN1CCCC(c2ccc(F)cc2)(c2ccc(F)cc2)C1=O)N1CCNCC1,,C1CCOC1,,,,test
US20160090374A1,CN[C@H]1CCN(c2nc(Cl)nc3cccc(C)c23)C1.N#Cc1cc(N)cc(N)c1>>CN[C@H]1CCN(c2nc(Nc3cc(N)cc(C#N)c3)nc3cccc(C)c23)C1,,CC(C)(C)O,,CCN(C(C)C)C(C)C,,test
US20030162777A1,COC(=O)C1CCc2ccccc2N1.O=C1CCC(=O)N1Br>>COC(=O)C1CCc2cc(Br)ccc2N1,,CN(C)C=O,O,,,test
US20070185140A1,CC1Cc2ccccc2N1.Clc1nc(Cl)c2[nH]cnc2n1>>Cc1cc2ccccc2n1-c1nc(Cl)nc2[nH]cnc12,,CCCCO,,,,test
US05728848,C/C=C\C.O.O=C1CCCCC1>>C1=CCOC2(CCCCC2)OC1,,c1ccccc1,,,,test
US20090023702A1,CS(=O)(=O)OC1CCN(C(=O)OCc2ccccc2)CC1.O=c1cc(O)cc[nH]1>>O=C(OCc1ccccc1)N1CCC(Oc2cc[nH]c(=O)c2)CC1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20110171133A1,Fc1ccc(Oc2ccccc2)cc1.O=S(=O)(O)Cl>>O=S(=O)(O)c1ccc(Oc2ccc(F)cc2)cc1,,ClCCl,,,,test
US20100009975A1,CN(C)CCCl.O=C1CSc2cc([N+](=O)[O-])ccc2N1>>CN(C)CCN1C(=O)CSc2cc([N+](=O)[O-])ccc21,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20090137580A1,CN1CCN(C(=O)c2ccc(N)cc2C(F)(F)F)CC1.Cn1ccc2ncnc(Oc3ccc(N)c(Cl)c3)c21.O=C(Cl)Oc1ccccc1>>CN1CCN(C(=O)c2ccc(NC(=O)Nc3ccc(Oc4ncnc5ccn(C)c45)cc3Cl)cc2C(F)(F)F)CC1,,CN1CCCC1=O,,c1ccncc1,,test
US20150368253A1,BrCc1ccccc1.C[C@@H](O)[C@H](NC(=O)OC(C)(C)C)C(=O)O>>C[C@@H](OCc1ccccc1)[C@H](NC(=O)OC(C)(C)C)C(=O)O,,CN(C)C=O,,[H-].[Na+],,test
US20130116232A1,COc1cc(F)cc(CO)c1.ClP(Cl)(Cl)(Cl)Cl>>COc1cc(F)cc(CCl)c1,,ClC(Cl)(Cl)Cl,,O=C([O-])[O-].[Na+].[Na+],,test
US20090111794A1,COC(=O)c1ccc(C=O)cc1.c1ccc2sc(Oc3ccc(CN4CC5CNCC5C4)cc3)nc2c1>>COC(=O)c1ccc(CN2CC3CN(Cc4ccc(Oc5nc6ccccc6s5)cc4)CC3C2)cc1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04290971,CCC(=O)NC(=S)Nc1c(Cl)cccc1Cl.CI>>CCC(=O)N=C(Nc1c(Cl)cccc1Cl)SC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05521177,CCc1nc2c(C)cc(NC(=NS(C)(=O)=O)N(C)C)cc2n1Cc1ccc(-c2ccccc2C(=O)OC)cc1>>CCc1nc2c(C)cc(NC(=NS(C)(=O)=O)N(C)C)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1,,CCO,,[Na+].[OH-],,test
US20040077605A1,C=C(Cl)CCl.O=[N+]([O-])c1ccc(Cl)c(S)c1>>C=C(Cl)CSc1cc([N+](=O)[O-])ccc1Cl,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US06291464B1,CC(=O)N1CCN(N=O)CC1C(=O)NCc1ccccc1>>CC(=O)N1CCN(N)CC1C(=O)NCc1ccccc1,[Zn],CC(=O)O,O,,,test
US20030017278A1,CCCCCOCCCCOc1ccc(B(O)O)c(F)c1F.Cc1ccccc1.O=C(O)c1ccc(OCc2ccccc2)cc1>>CCCCCOCCCCOc1ccc(-c2ccc(C(=O)OCC)cc2)c(F)c1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20110178060A1,CCOC(=O)C1=C(c2ccc(F)cc2)CN(Cc2ccccc2)CC1.Cl>>Cl.O=C(O)C1=C(c2ccc(F)cc2)CN(Cc2ccccc2)CC1,,CC(=O)O,,,,test
US20030036655A1,BrCc1ccc(Br)cc1.CC(C)O>>CC(C)OCc1ccc(Br)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20060264460A1,Cn1cnc(C=O)c1.N#Cc1cnc2c(Cl)cc(N)cc2c1Nc1ccc(F)c(Cl)c1>>Cn1cnc(CNc2cc(Cl)c3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)c1,,CCO,,[BH3-]C#N.[Na+],,test
US20120095211A1,COC(=O)[C@@H]1[C@H](C)[C@@H](O)CN1C(=O)OC(C)(C)C>>C[C@H]1[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C[C@@H]1O,,C1CCOC1,O,[Li+].[OH-],,test
US20080214613A1,CN1CCCC1CCNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]>>CN1CCCC1CCNc1ccc([N+](=O)[O-])cc1N,,CCO,,Cl,O,test
US20160002205A1,CCOC(=O)c1cccc(-n2nccc2-c2cc(N)ncc2-c2ccc(N3CCN(C)CC3)cc2OC)c1>>COc1cc(N2CCN(C)CC2)ccc1-c1cnc(N)cc1-c1ccnn1-c1cccc(C(=O)O)c1,,CO,,Cl,[Na+].[OH-],test
US20110082172A1,C=C(C)CC1(C(=O)OC)CC(=O)N(c2c(C)cccc2C)C1>>C=C(C)CC1(C(=O)O)CC(=O)N(c2c(C)cccc2C)C1,,CO,,[Li+].[OH-],,test
US06326369B1,COc1cc2c(c(OC)c1OC)C(=O)C(CCCCCCC1Cc3cc(OC)c(OC)c(OC)c3C1=O)C2>>COc1cc2c(c(OC)c1OC)CC(CCCCCCC1Cc3cc(OC)c(OC)c(OC)c3C1)C2,[Pd],CC(=O)O,,[O-][Cl+3]([O-])([O-])O,,test
US06005008,Nc1ccc(Br)cc1SSc1cc(Br)ccc1N.O=C=Nc1ccccc1Br>>O=C(Nc1ccc(Br)cc1S)Nc1ccccc1Br,,CN(C)C=O,ClCCl,,,test
US20100029609A1,CCOC(=O)C1(NC(=O)OCc2ccccc2)CN(C(=O)OC(C)(C)C)C1>>CCOC(=O)C1(N)CN(C(=O)OC(C)(C)C)C1,[Pd],CCO,,C1=CCCCC1,,test
US20140142114A1,CI.N#Cc1ccc(NC2CCC(OCC(=O)N3CCN(c4ccc5cc(C(F)(F)F)ccc5n4)CC3)CC2)cc1C(F)(F)F>>CN(c1ccc(C#N)c(C(F)(F)F)c1)C1CCC(OCC(=O)N2CCN(c3ccc4cc(C(F)(F)F)ccc4n3)CC2)CC1,,C1CCOC1,O,[H-].[Na+],,test
US04795809,O=C(O)CCN[C@H](C(=O)OCc1ccccc1)C(O)CCNC(=O)OCc1ccccc1>>O=C(NCCC(O)C(C(=O)OCc1ccccc1)N1CCC1=O)OCc1ccccc1,,CC#N,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20050267095A1,CS(=O)(=O)OS(C)(=O)=O.c1cc(C2(CN3CCNCC3)CCCCC2)ccc1OCCCN1CCCC1>>CS(=O)(=O)N1CCN(CC2(c3ccc(OCCCN4CCCC4)cc3)CCCCC2)CC1,,ClCCl,,c1ccncc1,,test
US20070066639A1,CC(C)=O.CCCCc1nc2c(N)nc3ccccc3c2n1CCCCON>>CCCCc1nc2c(N)nc3ccccc3c2n1CCCCON=C(C)C,,CO,,,,test
US20160016966A1,COCCO.Clc1cc(Br)ccn1>>COCCOc1cc(Br)ccn1,,C1CCOC1,,O,[H-].[Na+],test
US20040002145A1,COc1ccc(COc2ccc(CC(C#N)=CN3CCOCC3)cc2OC)cc1.Nc1ccccc1>>COc1ccc(COc2ccc(CC(C#N)=CNc3ccccc3)cc2OC)cc1,,CC(C)O,,Cl,O,test
US05208247,CCCCCCCCCCCCCCBr.COC(=O)c1ccccc1O>>CCCCCCCCCCCCCCOc1ccccc1C(=O)OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160120868A1,CC(C)(C)OC(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4ccccc4)c(Cl)c3)c3c(N)ncnc32)C1>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)c(Cl)c1)nn2[C@@H]1CCCNC1,,C1COCCO1,,Cl,O=C([O-])O.[Na+],test
US20150218156A1,CO.O=c1[nH]c(=O)n(CCc2ccccc2)nc1O>>Cc1cccc(CCn2nc(O)c(=O)[nH]c2=O)c1,,CCOC(C)=O,,,,test
US20090325956A1,CNc1ccccc1Cl.COC(=O)c1cccc(C=O)c1>>COC(=O)c1cccc(CN(C)c2ccccc2Cl)c1,,CC#N,,[Na+].[OH-],,test
US20050124654A1,C1CCNCC1.CN(C(=O)OC(C)(C)C)C1CCOc2cc(C=O)ccc21>>CN(C(=O)OC(C)(C)C)C1CCOc2cc(CN3CCCCC3)ccc21,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090143597A1,Ic1ccccc1.OB(O)c1ccccc1>>c1ccc(-c2ccccc2)cc1,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20030065018A1,N#CCC#N.N#Cc1cncc(C=O)c1.Oc1cccc2[nH]ccc12>>N#CC1=C(N)OC2C3=CC=NC3=CC=C2C1c1cncc(C#N)c1,,CCO,,C1CCNCC1,,test
US20040152721A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN1C(=O)C(Br)=C(c2c[nH]c3ccccc23)C1=O>>CN1C(=O)C(Br)=C(c2cn(C(=O)OC(C)(C)C)c3ccccc23)C1=O,CN(C)c1ccncc1,C1CCOC1,,,,test
US20100093740A1,COC(=O)CBr.Oc1cccc(C(F)(F)F)c1>>COC(=O)COc1cccc(C(F)(F)F)c1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140088124A1,CC(C)(C)OC(=O)N1CCC(O)CC1.COC(=O)c1cc(O)ccn1>>COC(=O)c1cc(OC2CCN(C(=O)OC(C)(C)C)CC2)ccn1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US08632792B2,CC(C)CCCCCCCCCCCCCCC(=O)O.CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O>>CC(C)CCCCCCCCCCCCCCC(=O)OC1(C)CCC(C(C)C)CC1,,Cc1ccccc1,,CCN(CC)CC,O=S(Cl)Cl,test
US05387710,COC(=O)N[C@@H](Cc1ccc(OC)cc1)C(=O)OCc1ccccc1>>COC(=O)N[C@@H](Cc1ccc(OC)cc1)C(=O)O,[Pd],O,,C1CCOC1,,test
US20130293094A1,Brc1cc(Br)cc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)c1.CC1(C)OB(c2cccc(-n3c4ccccc4c4ccccc43)c2)OC1(C)C>>Brc1cc(-c2cccc(-n3c4ccccc4c4ccccc43)c2)cc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[K+].[K+],,test
US20080293696A1,CS(=O)(=O)Cl.OCc1ccnc(Cl)c1>>ClCc1ccnc(Cl)c1,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,,test
US20060270686A1,CC(=O)Nc1cc(C(=O)c2ccnc(Cl)c2)cc(-c2cccc3c2ccn3[Si](C(C)C)(C(C)C)C(C)C)c1.CO>>COc1cc(C(=O)c2cc(NC(C)=O)cc(-c3cccc4[nH]ccc34)c2)ccn1,,CO,,C[O-].[Na+],,test
US05587389,Cc1c(SCc2ccsc2)ccnc1CCl.Sc1nc2ccccc2[nH]1>>Cc1c(SCc2ccsc2)ccnc1CSc1nc2ccccc2[nH]1,,CCO,,Cl,[Na+].[OH-],test
US20060205715A1,NC(=O)c1ccc(Oc2ccc3c(c2)CCCC3=O)nc1.NCCc1cccs1>>NC(=O)c1ccc(Oc2ccc3c(c2)CCCC3NCCc2cccs2)nc1,Cl[Ti](Cl)(Cl)Cl,,,[BH3-]C#N.[Na+],,test
US06521643B1,CC(C)(C)OC(=O)NC(=Nc1cccc(-c2ncccc2N)c1)NC(=O)OC(C)(C)C.Cl.ClCCl>>Cl.Cl.N=C(N)Nc1cccc(-c2ncccc2N)c1,,C1COCCO1,ClCCl,,,test
US20090131503A1,CN(C(=O)OC(C)(C)C)C1CC=C(c2c[nH]c3ccc([N+](=O)[O-])cc23)CC1>>CN(C(=O)OC(C)(C)C)C1CCC(c2c[nH]c3ccc(N)cc23)CC1,[Pd],CO,N,,,test
US20090093484A1,COC(=O)COc1ccc(O)cc1C.OC/C=C(/c1ccccc1)c1ccc(I)cc1>>COC(=O)COc1ccc(OC/C=C(/c2ccccc2)c2ccc(I)cc2)cc1C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20140140956A1,CC(C)N.COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCBr)c(-c4ccc(S(C)(=O)=O)cc4)c3)nc2c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCNC(C)C)c(-c4ccc(S(C)(=O)=O)cc4)c3)nc2c1,,CS(C)=O,,,,test
US20050197350A1,Cc1cnc(N[C@H]2CC[C@@H](NC(=O)OC(C)(C)C)CC2)nc1N(C)C.O=C(Br)CBr>>Cc1cnc(NC2CCC(NC(=O)CBr)CC2)nc1N(C)C,,ClCCl,,,,test
US20060063814A1,COC(=O)c1csc(NC(=O)[C@H](Cc2ccccc2C#N)NC(=O)OC(C)(C)C)n1>>COC(=O)c1csc(NC(=O)[C@@H](N)Cc2ccccc2C#N)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130115190A1,COc1ccc2c(Cl)ncc(O)c2c1.FC(F)CBr>>COc1ccc2c(Cl)ncc(OCC(F)F)c2c1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20160122364A1,Brc1cnc2c(N3CCOCC3)snc2c1.OB(O)c1ccc2c(c1)OCO2>>c1cc2c(cc1-c1cnc3c(N4CCOCC4)snc3c1)OCO2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US04309442,COCCCC(N)(C#N)CF.O=C(Cl)c1ccccc1C(=O)Cl>>COCCCC(C#N)(CF)N1C(=O)c2ccccc2C1=O,,ClCCl,,CCN(CC)CC,,test
US20100190766A1,C1COCCN1.CC(C)(C)OC(=O)N1CCC(c2ccc(CO)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccc(CN3CCOCC3)cc2)CC1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,CS(=O)(=O)Cl,test
US20160251361A1,Nc1ncc(Br)nn1.OB(O)c1ccc(F)cc1F>>Nc1ncc(-c2ccc(F)cc2F)nn1,,COCCOC,,ClCCl,O=C([O-])[O-].[Na+].[Na+],test
US20090105211A1,COC(=N)c1ccc(C)c(NC(=O)c2ccc(Nc3nc(-c4ccccc4)c4ccccc4n3)cc2)c1.NNC=O>>Cc1ccc(-c2ncn[nH]2)cc1NC(=O)c1ccc(Nc2nc(-c3ccccc3)c3ccccc3n2)cc1,,CCO,,CCN(C(C)C)C(C)C,,test
US04282212,CC(C)(C)C(=O)N=C=O.N#CC1CN1>>CC(C)(C)C(=O)NC(=O)N1CC1C#N,,Cc1ccccc1,,,,test
US20160213648A1,Cc1nc2ccccc2c(=O)o1.Nc1cccc(-n2nn[nH]c2=O)c1>>Cc1nc2ccccc2c(=O)n1-c1cccc(-n2nn[nH]c2=O)c1,,CC(=O)O,,,,test
US03953499,BrP(Br)Br.CCCCCC(C)=CCC#CCO>>CCCCCC(C)=CCC#CCBr,,c1ccncc1,,CCOCC,,test
US20090093456A1,CC(C)(C)OC(=O)N1CC(O)C1.COc1cc([N+](=O)[O-])ccc1F>>COc1cc([N+](=O)[O-])ccc1OC1CN(C(=O)OC(C)(C)C)C1,,C1CCOC1,O,CC(C)(C)O[K],,test
US20090023731A1,Nc1cccc(OCc2ccccc2)c1.O=C=Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)Nc1cccc(OCc2ccccc2)c1,,CN(C)C=O,,CO,ClCCl,test
US20140371203A1,BrCC1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1.CN1CCCC1CCN>>CN1CCCC1CCNCC1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1,,CC#N,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20140350193A1,COP(=O)(OC)C(CC(=O)OC(C)(C)C)P(=O)(OC)OC>>COP(=O)(OC)C(CC(=O)O)P(=O)(OC)OC,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150111038A1,CON(C)C(=O)c1ccc(F)c(C(F)(F)F)c1F.C[Mg]Br>>CC(=O)c1ccc(F)c(C(F)(F)F)c1F,,C1CCOC1,,,,test
US20130281392A1,Nc1cc(Oc2ccc(F)cc2F)c(Cl)cc1[N+](=O)[O-]>>Nc1cc(Cl)c(Oc2ccc(F)cc2F)cc1N,[Zn],CCO,,Cl,,test
US20090247579A1,CCI.COc1ccc(NC(=O)C=Cc2ccccc2)cc1>>CCN(C(=O)C=Cc1ccccc1)c1ccc(OC)cc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20140005213A1,C[C@@H](c1ccc2nnc(-c3ccc4cccc(C(C)(C)C)c4n3)n2c1)N1CC[C@H](NC(=O)OC(C)(C)C)C1>>C[C@@H](c1ccc2nnc(-c3ccc4cccc(C(C)(C)C)c4n3)n2c1)N1CC[C@H](N)C1,,CC(C)O,ClCCl,Cl,,test
US04272437,CC(CCC#N)OS(C)(=O)=O.[N-]=[N+]=[N-]>>CC(CCC#N)N=[N+]=[N-],,CCO,,O,,test
US20110201555A1,NO.O=Cc1c(-n2cccc2)n(-c2ccc(O)cc2)c2ccccc12>>ON=Cc1c(-n2cccc2)n(-c2ccc(O)cc2)c2ccccc12,,CCO,,Cl,c1ccncc1,test
US20120208811A1,Cc1ccc(S(=O)(=O)OC2COC2)cc1.Cc1nc2cc(-n3ncc(C(=O)c4cc5ccc(O)cc5[nH]4)c3N)ccc2[nH]1>>Cc1nc2cc(-n3ncc(C(=O)c4cc5ccc(OC6COC6)cc5[nH]4)c3N)ccc2[nH]1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150361098A1,COc1ccc(CNc2nc3c(C)cccc3c3nc(CN4Cc5cccnc5C4)nn23)c(OC)c1>>Cc1cccc2c1nc(N)n1nc(CN3Cc4cccnc4C3)nc21,,O=C(O)C(F)(F)F,,,,test
US20150232459A1,COC(=O)NCCCn1nc([C@@H](C)N(C(=O)[C@H]2CN(Cc3ccccc3)[C@@H](CO)CO2)C2CC2)c2ccc(C)nc21.CS(=O)(=O)Cl>>COC(=O)NCCCn1nc([C@@H](C)N(C(=O)[C@H]2CN(Cc3ccccc3)[C@@H](COS(C)(=O)=O)CO2)C2CC2)c2ccc(C)nc21,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20020107269A1,CN.Cc1ccc(Cl)c([N+](=O)[O-])c1>>CNc1ccc(C)cc1[N+](=O)[O-],,CCO,O,,,test
US20120035070A1,Br[Mg]Cc1ccc2ccccc2c1.CCOC(=O)C(OCC)OCC>>CCOC(OCC)C(=O)Cc1ccc2ccccc2c1,,C1CCOC1,,CCOCC,[Cl-].[NH4+],test
US20060194843A1,CCOC(=O)c1n[nH]cc1N.O=C(O)c1c(F)cccc1F>>CCOC(=O)c1n[nH]cc1NC(=O)c1c(F)cccc1F,,CN(C)C=O,O,ClCCCl,On1nnc2ccccc21,test
US20160214971A1,COc1cc(C(=O)NS(C)(=O)=O)c(F)cc1-c1cnc(F)c(Cl)c1.Cc1ccc(Cl)c(O)c1>>COc1cc(C(=O)NS(C)(=O)=O)c(F)cc1-c1cnc(Oc2cc(C)ccc2Cl)c(Cl)c1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110136763A1,CCOC(=O)CC1OB(O)c2cc(Oc3ccnc(NCCNC(=O)OC(C)(C)C)n3)cc(C)c21>>Cc1cc(Oc2ccnc(NCCNC(=O)OC(C)(C)C)n2)cc2c1C(CC(=O)O)OB2O,,C1CCOC1,O,[Li+].[OH-],,test
US04812470,N#CCCl.[N-]=[N+]=CC(=O)Cc1ccccc1>>ClCc1ncc(Cc2ccccc2)o1,,ClCCl,,CCOCC,FB(F)F,test
US06046212,Cc1cc(Br)ccc1O.N#C[Cu]C#N>>Cc1cc(C#N)ccc1O,,CCOC(C)=O,CN1CCCC1=O,Cl,O,test
US04654343,CCN(C(C)=O)c1cccc(-c2ccc(Cl)nn2)c1.CCNC(=S)NN>>CCNc1nnc2ccc(-c3cccc(N(CC)C(C)=O)c3)nn12,,CCO,,,,test
US06015774,Cn1c(C(F)(F)F)cnc(-c2cc([N+](=O)[O-])c(Cl)cc2Cl)c1=O>>Cn1c(C(F)(F)F)cnc(-c2cc(N)c(Cl)cc2Cl)c1=O,[Fe],CC(=O)O,,O,,test
US20030186989A1,C=CCN(CC=C)[C@H](C)c1ccc(Br)cc1.CC(C)=O>>C=CCN(CC=C)[C@H](C)c1ccc(C(C)(C)O)cc1,,C1CCOC1,,[Li]CCCC,,test
US04420555,C=CC(=O)OC(C)C.CCNc1cccc(C)c1>>CCN(CCC(=O)OC(C)C)c1cccc(C)c1,,CCOCC,,CC(=O)O,,test
US20110071175A1,COC(=O)Cn1c(C)c(Cc2cnccc2S(=O)(=O)c2ccccc2)c2cc(F)ccc21>>Cc1c(Cc2cnccc2S(=O)(=O)c2ccccc2)c2cc(F)ccc2n1CC(=O)O,,C1CCOC1,,Cl,[Na+].[OH-],test
US20010031865A1,CC(O)C(C)O.COC(OC)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)ccc1Cl>>CC1OC(c2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)ccc2Cl)OC1C,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20140256719A1,CC(C)(C)NS(=O)(=O)c1cc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)ccn3n2)cnc1C(F)F>>NS(=O)(=O)c1cc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)ccn3n2)cnc1C(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070173506A1,CC(C)(O)C#Cc1csc(N(C[C@H](Cc2ccc(C(F)(F)F)cc2)NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n1.O=C1CCC(=O)N1Br>>CC(C)(O)C#Cc1nc(N(C[C@H](Cc2ccc(C(F)(F)F)cc2)NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)sc1Br,,ClC(Cl)(Cl)Cl,,,,test
US20090163524A1,CC(C)(C)OC(=O)NC1(C(=O)O)CCN(c2ncnc3[nH]ccc23)CC1.NC(CCCO)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)NC1(C(=O)NC(CCCO)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160108035A1,CCOC(=O)C1(Sc2ccnc3ccc(OCCOC)cc23)CCC1>>COCCOc1ccc2nccc(SC3(C(=O)O)CCC3)c2c1,,C1CCOC1,O,[Na+].[OH-],,test
US20140275015A1,COc1ccc(C(C)(O)CN2CC(C)c3c(nnn3-c3ccc(F)cc3)C2C)cc1>>CC1CNC(C)c2nnn(-c3ccc(F)cc3)c21,,C1COCCO1,Cl,,,test
US20150119393A1,CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@H]2[C@@H]1OC[C@H]2Oc1nc2cc(Cl)c(-c3ccc([C@@H]4CC[C@@H](O)CC4)cc3)nc2n1COCC[Si](C)(C)C.CCN=C=O>>CCNC(=O)O[C@@H]1CC[C@@H](c2ccc(-c3nc4c(cc3Cl)nc(O[C@@H]3CO[C@@H]5[C@H](O[Si](C)(C)C(C)(C)C)CO[C@@H]53)n4COCC[Si](C)(C)C)cc2)CC1,,C1CCOC1,,CCN(CC)CC,,test
US04658039,C=CCOC(=O)COC(=O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12>>COc1ccc2c(c1)c(CC(=O)OCC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1,,C1CCOC1,,C1CCNCC1,Cl,test
US20150299190A1,CC(C)(C)OC(=O)c1ccc(N2CCOCS2(=O)=O)cc1Cl>>O=C(O)c1ccc(N2CCOCS2(=O)=O)cc1Cl,,ClCCl,O=C(O)C(F)(F)F,,,test
US20050137220A1,COc1ccc2[nH]c3c(c2c1)CCCCC3=O.NO>>COc1ccc2[nH]c3c(c2c1)CCCCC3=NO,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US05405861,C[C@@H](OC1CCCCO1)C1(c2ccc(F)cc2F)CO1.c1c[nH]cn1>>C[C@@H](OC1CCCCO1)C(O)(Cn1ccnc1)c1ccc(F)cc1F,,CN(C)C=O,,O,[H-].[Na+],test
US20070004675A1,O=C(c1cc2nccc(Oc3ccc([N+](=O)[O-])cc3F)c2s1)N1CCCC1>>Nc1ccc(Oc2ccnc3cc(C(=O)N4CCCC4)sc23)c(F)c1,,C1CCOC1,CO,[BH4-].[Na+],,test
US05166204,CC(C)=O.Cn1ccc2ccccc21>>Cn1c(C(C)(C)O)cc2ccccc21,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20090258866A1,C=CCCC=O.C=Cc1ccccc1Br.CC(C)[Si](Cl)(C(C)C)C(C)C>>C=CCCC(O[Si](C(C)C)(C(C)C)C(C)C)c1ccccc1C=C,,C1CCOC1,c1ccccc1,[Li]CCCC,,test
US20090291950A1,COc1ccc2c(c1OC1CCCC1)OCC2=O>>COc1ccc2c(c1OC1CCCC1)OCC2O,,CO,,C1CCOC1,[BH4-].[Na+],test
US20140005175A1,COCCOc1cccc([N+](=O)[O-])c1>>COCCOc1cccc(N)c1,[Pd],CO,,,,test
US20120309966A1,Cc1nccn2c(C3CN(C(=O)OCc4ccccc4)C3)nc(Br)c12>>Cc1nccn2c(C3CNC3)nc(Br)c12,,Cl,,,,test
US04851519,O=C(Cl)C(=O)Cl.O=C(O)C(c1ccccc1)(c1ccccc1)c1ccccc1>>O=C(Cl)C(c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,c1ccccc1,,,,test
US20120309796A1,CC(C)(C)OC(=O)COc1cccc2c1CCCCC2NS(=O)(=O)c1cc(F)cc(C(F)(F)F)c1>>O=C(O)COc1cccc2c1CCCCC2NS(=O)(=O)c1cc(F)cc(C(F)(F)F)c1,,C1CCOC1,,[Na+].[OH-],,test
US05840732,CCOC(=O)CCCBr.Nc1cc[nH]c(=S)n1>>CCOC(=O)CCCSc1nccc(N)n1,,CCO,,CCN(CC)CC,,test
US20130085131A1,CCNC.O=Cc1cc2c(F)cccc2nc1CN1C(=O)c2ccccc2C1=O>>CCN(C)Cc1cc2c(F)cccc2nc1CN1C(=O)c2ccccc2C1=O,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090239845A1,C=Cc1ccc(C(=O)Nc2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)c(F)c1.O=[O+][O-]>>Cc1cc(NC(=O)c2ccc(C=O)cc2F)nn1Cc1cc(Cl)ccc1OCC(C)C,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090233915A1,CC(C)(C)[Si](C)(C)OCCONC(=O)c1cc(C=O)c(F)c(F)c1Nc1ccc(I)cc1F>>O=Cc1cc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)c(F)c1F,,C1CCOC1,O,Cc1ccc(S(=O)(=O)O)cc1,,test
US05338849,N#CC1(n2cc(C=O)c3cccnc32)CCCC1>>N#CC1(n2cc(CO)c3cccnc32)CCCC1,,CO,,O,[BH4-].[Na+],test
US06166006,CCOC(=O)CCS.O=Cc1cc(Br)ccc1F>>CCOC(=O)C1=Cc2cc(Br)ccc2SC1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080070928A1,Cc1ccc(Sc2cc3nc(-c4ccccn4)[nH]c3cc2Oc2cccnc2)cn1.O=S([O-])OO>>Cc1ccncc1S(=O)(=O)c1cc2nc(-c3ccccn3)[nH]c2cc1Oc1cccnc1,,C1CCOC1,,O,,test
US05302607,O=C(Cl)c1cccc2nnsc12.OC/C=C/c1ccccc1>>O=C(OCC=Cc1ccccc1)c1cccc2nnsc12,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20100190981A1,N#CC[C@H](C1CC1)n1cc(-c2ncnc3[nH]ccc23)cn1.O=P(O)(O)O>>N#CC[C@H](C1CC1)n1cc(-c2ncnc3[nH]ccc23)cn1.O=P(O)(O)O,,CC(C)O,,,,test
US06248740B1,Clc1ccc2ncnn2n1.NCCCO>>OCCCNc1ccc2ncnn2n1,,CCO,,,,test
US04829081,BrBr.O=C(Cc1ccc(F)cc1)c1ccccc1>>O=C(c1ccccc1)C(Br)c1ccc(F)cc1,,ClC(Cl)Cl,,,,test
US20090143353A1,CN(C)[C@H]1CCNC1.Cc1c(-c2ccccc2)c(F)c2oc(C3=CCCC3)nc2c1C#N>>Cc1c(-c2ccccc2)c(N2CC[C@H](N(C)C)C2)c2oc(C3=CCCC3)nc2c1C#N,,CS(C)=O,,CCN(CC)CC,,test
US20150119412A1,CCOc1c(CN2CCC(n3ccc(C(=O)OC)c(CC)c3=O)CC2)cc(C2CC2)c(-c2ccc(F)cc2)c1F>>CCOc1c(CN2CCC(n3ccc(C(=O)O)c(CC)c3=O)CC2)cc(C2CC2)c(-c2ccc(F)cc2)c1F,,CO,,Cl,[Na+].[OH-],test
US08785481B2,COc1cccc(CO)n1.Oc1ccc2c(nnn2CC2CC2)c1Br>>COc1cccc(COc2ccc3c(nnn3CC3CC3)c2Br)n1,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05804593,COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc(OC)cc1>>COc1ccc(S(=O)(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)O)cc1,,CCO,,Cl,[Na+].[OH-],test
US20150353559A1,CC(C)(C)OC(=O)N1C[C@@H]2CCN(C(=O)CBr)CC[C@@H]2C1.Oc1cc(Cl)ccc1C(F)(F)F>>CC(C)(C)OC(=O)N1C[C@@H]2CCN(C(=O)COc3cc(Cl)ccc3C(F)(F)F)CC[C@@H]2C1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080207654A1,CCCc1nc(CC)n(-c2ccc(N3CCOCC3)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCc1nc(CC)n(-c2ccc(N3CCOCC3)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,O,,CS(C)=O,[Cl-].[Na+],test
US20070254867A1,COC(=O)C(C)(C)c1ccc2c(c1)NC(=O)c1ccc(-c3cccc4cnccc34)cc1N2>>CC(C)(C(=O)O)c1ccc2c(c1)NC(=O)c1ccc(-c3cccc4cnccc34)cc1N2,,C1CCOC1,O,[Li]O,,test
US20070281963A1,CC(=O)Cl.Nc1c2c(=O)[nH]c3ccccc3c2nn1-c1cc(O)ccc1Cl>>CC(=O)Oc1ccc(Cl)c(-n2nc3c(c2N)c(=O)[nH]c2ccccc23)c1,,O,,CCN(CC)CC,ClCCl,test
US20150065715A1,O=C(O)c1cnn(-c2ccc(Cl)cc2)c1.O=S(Cl)Cl>>O=C(Cl)c1cnn(-c2ccc(Cl)cc2)c1,,Cc1ccccc1,,CN(C)C=O,,test
US20150368265A1,CNC(=O)c1c(-c2ccc(Oc3ccc(F)cc3)nc2)oc2cc(N)c(Br)cc12.CS(=O)(=O)Cl>>CNC(=O)c1c(-c2ccc(Oc3ccc(F)cc3)nc2)oc2cc(NS(C)(=O)=O)c(Br)cc12,CN(C)c1ccncc1,c1ccncc1,,,,test
US20080262230A1,FC(F)(F)c1cc(CBr)cc(C(F)(F)F)c1.OCC1(c2ccccc2)OCCO1>>FC(F)(F)c1cc(COCC2(c3ccccc3)OCCO2)cc(C(F)(F)F)c1,,CN(C)C=O,,O,[H-].[Na+],test
US05998433,Cc1ccc(S(=O)(=O)Cl)cc1.OCCN(CCCCCCc1ccccc1)Cc1ccoc1>>ClCCN(CCCCCCc1ccccc1)Cc1ccoc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US06395751B1,CCOC(=O)N1c2cc(C(=O)OC)c(OC)cc2[C@H](NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C[C@@H]1C.COC(=O)Cl>>CCOC(=O)N1c2cc(C(=O)OC)c(OC)cc2[C@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(=O)OC)C[C@@H]1C,,ClCCl,,c1ccncc1,,test
US20120291159A1,ON=Cc1cccc(-n2cncn2)c1.[O-]Cl>>ON=C(Cl)c1cccc(-n2cncn2)c1,,C1CCOC1,,Cl,,test
US20110021537A1,CC(C)(C)OC(=O)N[C@@H](CCC1=NNNN1Cc1ccccc1)C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](CCc1nn[nH]n1)C(=O)O,[Pd],CCOC(C)=O,,,,test
US20060111353A1,CCOC(=O)/C(Br)=C/C1CCCCC1.CSc1ccc(B(O)O)cc1>>CCOC(=O)/C(=C/C1CCCCC1)c1ccc(SC)cc1,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20160222005A1,Brc1ccc(COc2ccccc2)cc1.CN(C)C=O>>O=Cc1ccc(COc2ccccc2)cc1,,C1CCOC1,,[Li]CCCC,,test
US20090030015A1,COC(=O)Cc1ccc(-c2ccccc2NC(=O)Cc2cccc(-c3ccc(OC)cc3OC)c2)s1>>COc1ccc(-c2cccc(CC(=O)Nc3ccccc3-c3ccc(CC(=O)O)s3)c2)c(OC)c1,,CC#N,,,,test
US05324804,O=C(O)/C=C/c1ccc(O)c(O)c1>>C=Cc1ccc(O)c(O)c1,,CN(C)C=O,,[Cl-].[Na+],,test
US06046192,CN(C)C(=O)COc1ccc2c(c1)C[C@@H](NC[C@H](O)c1ccc(O)cc1)CC2.Cl>>CN(C)C(=O)COc1ccc2c(c1)C[C@@H](NC[C@H](O)c1ccc(O)cc1)CC2.Cl,,CCO,,,,test
US04219649,CCc1c(C)nc2cccc(C)n2c1=O>>CCc1c(C)nc2n(c1=O)C(C)CCC2,,CCO,,,,test
US20070249607A1,CC(C)(C)OC(=O)N1CCC(COCc2cc([N+](=O)[O-])cc(C(F)(F)F)c2)(c2ccccc2)CC1>>CC(C)(C)OC(=O)N1CCC(COCc2cc(N)cc(C(F)(F)F)c2)(c2ccccc2)CC1,[Pd],CO,,,,test
US05739127,CCNCC.Clc1nc(Cl)c2ccccc2n1>>CCN(CC)c1nc(Cl)nc2ccccc12,,CCOCC,,,,test
US20130261106A1,CCC1C=C(c2ccc([N+](=O)[O-])c(OC(C)C)c2)CCN1C(=O)OC(C)(C)C>>CCC1CC(c2ccc(N)c(OC(C)C)c2)CCN1C(=O)OC(C)(C)C,[Pd],CO,,O=C[O-].[NH4+],,test
US20040087798A1,Cc1ncc(-c2cccc(N)c2)n1C.O=C(O)C=Cc1ccc(Cl)cc1>>Cc1ncc(-c2cccc(NC(=O)/C=C/c3ccc(Cl)cc3)c2)n1C,,CC(=O)N(C)C,CCOC(C)=O,,,test
US20050113580A1,CCOC(=O)C1CCN(c2cccc(O)c2)CC1.OCCCN(Cc1cccc(C(F)(F)F)c1Cl)CC(c1ccccc1)c1ccccc1>>CCOC(=O)C1CCN(c2cccc(OCCCN(Cc3cccc(C(F)(F)F)c3Cl)CC(c3ccccc3)c3ccccc3)c2)CC1,,Cc1ccccc1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090257979A1,CCOC(=O)C(=Cc1cccs1)c1ccccn1>>CCOC(=O)C(Cc1cccs1)c1ccccn1,[Pd],CCO,,,,test
US20060160802A1,O=C(O)C1(CNOCc2ccccc2)CCCC1.O=CO>>O=CN(CC1(C(=O)O)CCCC1)OCc1ccccc1,,ClCCl,,CC(=O)OC(C)=O,,test
US20030153578A1,CCN(CC)CC.O[C@@H]1CCCC[C@H]1N1CCC(Cc2ccc(Cl)cc2)CC1>>N[C@@H]1CCCC[C@H]1N1CCC(Cc2ccc(Cl)cc2)CC1,,ClCCl,,CS(=O)(=O)Cl,,test
US20090061471A1,CCO.COC(=O)C(C)c1ccc(CC(C)C)cc1>>COC(=O)C(C)c1ccc(CC(C)(C)O)cc1,,CCO,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20110065691A1,CCN.CCOC(=O)CN1CCN(c2ccc(OC)c3nc(C(F)(F)F)ccc23)C[C@@H]1Cc1ccccc1>>CCNC(=O)CN1CCN(c2ccc(OC)c3nc(C(F)(F)F)ccc23)C[C@@H]1Cc1ccccc1,,C1CCOC1,,,,test
US20040058978A1,N#Cc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1>>NCc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1,[Ni],N,,[H][H],,test
US04282361,Cc1n[nH]c(C(N)=O)c1[N+](=O)[O-].O=CO>>Cc1n[nH]c(C(N)=O)c1NC=O,[Pd],O=CO,,CCO,O,test
US04642351,Cc1cccc(N=C=O)c1.O=C1NCCO1>>Cc1cccc(N2CCNC2=O)c1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20160074419A1,C/C=C1/C(=O)[C@H]2[C@@H]3CC[C@H]([C@H](C)CCC(=O)OC)[C@@]3(C)CC[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12>>C/C=C1\C(=O)[C@H]2[C@@H]3CC[C@H]([C@H](C)CCC(=O)O)[C@@]3(C)CC[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12,,O,,,,test
US20120202802A1,C=CCB1OC(C)(C)C(C)(C)O1.N.O=C1CC[C@@H](C(=O)OCc2ccccc2)C1>>C=CCC1(N)CC[C@@H](C(=O)OCc2ccccc2)C1,,CO,,,,test
US20060025459A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H]1CO1.N>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN,,CO,,,,test
US20080299520A1,C=C(C)C(=O)OCCN(C)C.CCCCCCCCCCCCCCCCBr>>C=C(C)C(=O)OCC.CCCCCCCCCCCCCCCC[NH+](C)C.[Br-],,CC(C)=O,,,,test
US20150299121A1,CCC(C)(C)C(=O)Cl.Cc1ccc(C(=O)Nc2cc(F)cc(CN3CCN[C@@H](C)C3)c2C)cn1>>CCC(C)(C)C(=O)N1CCN(Cc2cc(F)cc(NC(=O)c3ccc(C)nc3)c2C)C[C@@H]1C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080132536A1,CCn1ncc2c(Cl)c(C(=O)Cl)cnc21.Cc1ccc([C@@H](C)N)cc1>>CCn1ncc2c(Cl)c(C(=O)N[C@H](C)c3ccc(C)cc3)cnc21,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20070276138A1,COCC(=O)OC.COc1cc(O[Si](C)(C)C(C)(C)C)ccc1C=O>>COC(=O)C(OC)C(O)c1ccc(O[Si](C)(C)C(C)(C)C)cc1OC,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20090054466A1,CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(-c3ccnc(F)c3)cc(-c3ccnc(F)c3)c2)c1CCC(=O)OCC>>O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccnc(F)c3)cc(-c3ccnc(F)c3)c2)c1CCC(=O)O,,[Na+],[OH-],,,test
US20110092490A1,CN(C(=O)OC(C)(C)C)c1nc(-c2ccccc2)c(-c2nc(N)nc(Nc3cccc([N+](=O)[O-])c3)n2)s1>>CNc1nc(-c2ccccc2)c(-c2nc(N)nc(Nc3cccc([N+](=O)[O-])c3)n2)s1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20050288273A1,CC(=O)NC[C@H]1CN(c2cc(F)c3c(c2F)CCCCC3=O)C(=O)O1.COC(OC)N(C)C>>CC(=O)NC[C@H]1CN(c2cc(F)c3c(c2F)CCCC(=CN(C)C)C3=O)C(=O)O1,,CCCO,,,,test
US20110281910A1,Brc1nccs1.CCCC[Sn](CCCC)(CCCC)c1nccs1>>c1csc(-c2nccs2)n1,,Cc1ccccc1,,,,test
US20100075948A1,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.COc1cc(N)c(Br)cc1C(=O)O.ClCCl>>COC(=O)c1cc(Br)c(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)cc1OC,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070276138A1,CN(C)CCCO.CS(=O)(=O)Cl>>CN(C)CCCOS(C)(=O)=O,,C1CCOC1,,CCN(CC)CC,,test
US06225352B1,CCOC(OCC)OCC.Oc1cccc(O)c1O>>CCOC1Oc2cccc(O)c2O1,,Cc1ccccc1,,,,test
US05753679,CS(=O)(=O)OCC1CCN(C(=O)c2ccccc2)CC1.Sc1ccccc1>>O=C(c1ccccc1)N1CCC(CSc2ccccc2)CC1,,C1CCOC1,CCCCCC,[Na+].[OH-],,test
US20150051171A1,CCOc1cccc(-n2nnn(C)c2=O)c1CBr.Oc1ccn(-c2ccc(Cl)cc2)n1>>CCOc1cccc(-n2nnn(C)c2=O)c1COc1ccn(-c2ccc(Cl)cc2)n1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20160039846A1,NC(=O)C(F)(F)F.O=S(Cl)c1ccc(Br)cc1>>O=C(NS(=O)c1ccc(Br)cc1)C(F)(F)F,,C1CCOC1,,[Li]CCCC,,test
US20020099042A1,C[C@H](NC(=O)c1ccc(Cc2ccccc2)[nH]1)C(=O)NC(C=O)CC(=O)O.C[C@H](NC(=O)c1ccc[nH]1)C(=O)NC(C=O)CC(=O)O>>C[C@@H](NC(=O)c1ccc[nH]1)C(=O)N[C@H]1CC(=O)O[C@@H]1OCc1ccccc1,,CO,,[Br-].[K+],,test
US20070254940A1,CSC(=N)c1cccs1.Nc1ccc2c(ccn2C2CCOCC2)c1>>N=C(Nc1ccc2c(ccn2C2CCOCC2)c1)c1cccs1,,CCO,,I,,test
US20150299194A1,CCOCc1nc2c(NC(c3ccccc3)(c3ccccc3)c3ccccc3)nc3cc(/C=C/C(=O)OCC)ccc3c2n1CC(C)(C)OCCNC(=O)OC(C)(C)C>>CCOCc1nc2c(NC(c3ccccc3)(c3ccccc3)c3ccccc3)nc3cc(CCC(=O)OCC)ccc3c2n1CC(C)(C)OCCNC(=O)OC(C)(C)C,[Pd],CCO,CCOC(C)=O,[H][H],,test
US20060116383A1,CC(C)(C)OC(=O)C[C@@H](N)c1ccccc1.O=[N+]([O-])c1ccccc1F>>CC(C)(C)OC(=O)C[C@@H](Nc1ccccc1[N+](=O)[O-])c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20120149684A1,CCc1cn(CCN2CCCC2)c(C2CCN(c3ncnc4c3[C@H](C)CC(=O)N4)CC2)n1.Cl>>CCc1cn(CCN2CCCC2)c(C2CCN(c3ncnc4c3[C@H](C)CC(=O)N4)CC2)n1.Cl,,ClCCl,,C1COCCO1,,test
US20120083488A1,CC1(C)OC[C@H](COc2ccc3c(c2)C(C)(C)c2[nH]c4c(Br)c(C#N)ccc4c2C3=O)O1.N#C[Cu]>>CC1(C)OC[C@H](COc2ccc3c(c2)C(C)(C)c2[nH]c4c(C#N)c(C#N)ccc4c2C3=O)O1,,CC(=O)N(C)C,,O,,test
US20020173518A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=[N+]([O-])c1ccc2nc[nH]c2c1>>Cc1ccc(S(=O)(=O)n2cnc3cc([N+](=O)[O-])ccc32)cc1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20160108033A1,C[Si](C)(C)CCOCn1nnc2cnc(CO)cc21>>C[Si](C)(C)CCOCn1nnc2cnc(C=O)cc21,O=[Mn]=O,ClCCl,,,,test
US05891901,COC(=O)CN=[N+]=[N-].CSc1ccc(C=O)cc1>>COC(=O)C(=Cc1ccc(SC)cc1)N=[N+]=[N-],,CO,O,C[O-].[Na+],,test
US20130102576A1,CC(C)(C)OC(=O)N(c1ccc2c(c1)oc(=O)n2CC(=O)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1)S(C)(=O)=O>>CS(=O)(=O)Nc1ccc2c(c1)oc(=O)n2CC(=O)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1,,ClCCl,,C1CCOC1,Cl,test
US20150080393A1,Cc1cc(Br)ccc1C(O)C(F)(F)F>>Cc1cc(Br)ccc1C(=O)C(F)(F)F,,ClCCl,O,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04321398,Cc1ccccc1O.ClCC1CO1>>Cc1ccccc1OCC1CO1,C1CCNCC1,,,,,test
US20110136792A1,COc1cc(F)c(F)cc1-c1ccc(OCc2cccc(C=O)c2)cc1>>COc1cc(F)c(F)cc1-c1ccc(OCc2cccc(CO)c2)cc1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20090286768A1,Nc1ncnn2c([C@@H]3CC[C@@H](CNC(=O)OCc4ccccc4)CC3)nc(-c3ccc(Oc4ccccc4)cc3)c12>>NC[C@@H]1CC[C@@H](c2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnn23)CC1,,C1COCCO1,,Cl,,test
US20150105317A1,CS(=O)(=O)Cl.C[C@@H]1O[C@@H](CCCO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@@H]1OCc1ccccc1>>C[C@@H]1O[C@@H](CCCOS(C)(=O)=O)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@@H]1OCc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080045528A1,CNC(=O)c1cc(Oc2ccc3nc(N[C@H]4CCCN(C(=O)OC(C)(C)C)C4)sc3c2)ccn1>>CNC(=O)c1cc(Oc2ccc3nc(N[C@H]4CCCNC4)sc3c2)ccn1,,Cl,,C1COCCO1,,test
US20090012074A1,CCC(=O)NC1CCc2cc(NS(=O)(=O)c3ccc(C(C)C)cc3)ccc2C1>>CCCN[C@@H]1CCc2cc(NS(=O)(=O)c3ccc(C(C)C)cc3)ccc2C1,,C1CCOC1,,Cl,,test
US05102667,CCCCOCN(Cc1ccccc1)C[Si](C)(C)C.O=C1C=CC(c2ccccc2F)(c2ccccc2F)CC1>>O=C1CCC(c2ccccc2F)(c2ccccc2F)C2CN(Cc3ccccc3)CC12,O=C(O)C(F)(F)F,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20100216792A1,CCC(=O)O.NCc1cnc(N2CCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)nc1C(F)(F)F>>CCC(=O)NCc1cnc(N2CCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)nc1C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20040220404A1,COC(=O)c1sc(-c2ccc(Cl)cc2)cc1N.COC(OC)N(C)C.COc1cc(N)ccc1OCC(C)(C)N1CCCC1>>COc1cc(-n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)ccc1OCC(C)(C)N1CCCC1,,CCO,,,,test
US05112860,CON=C(C(=O)OC)c1ccccc1COc1ccccc1Cl>>CON=C(C(=O)O)c1ccccc1COc1ccccc1Cl,,[K+],[OH-],Cl,,test
US20100331287A1,CCOC1=N[C@H](C(C)C)C(OCC)=NC1.COCCCn1ncc2ccc(C[C@@H](CBr)C(C)C)cc21>>CCOC1=N[C@H](C(C)C)C(OCC)=N[C@H]1C[C@H](Cc1ccc2cnn(CCCOC)c2c1)C(C)C,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US04642313,CCOC(=O)CC(NC(=O)C1CCCCC1)C(=O)c1ccco1>>CCOC(=O)Cc1nc(C2CCCCC2)oc1-c1ccco1,,ClC(Cl)Cl,,O=P(Cl)(Cl)Cl,,test
US20050009895A1,CC(=O)Cl.COc1cc(C(=O)NCc2ccc(-c3noc(C)n3)cc2NCCN)cc(OC)c1C>>COc1cc(C(=O)NCc2ccc(-c3noc(C)n3)cc2NCCNC(C)=O)cc(OC)c1C,,ClCCl,,c1ccncc1,,test
US20150252008A1,N#Cc1ccc(Oc2c(C3CCC3)ccc(-c3cnc(N)cn3)c2F)cc1.O=S(=O)(O)O>>NC(=O)c1ccc(Oc2c(C3CCC3)ccc(-c3cnc(N)cn3)c2F)cc1,,O=C(O)C(F)(F)F,,,,test
US20070276000A1,CCCCCCCCc1cc2cc(OC)ccc2c(O)c1-c1ccccc1.O=Cc1ccc(F)cc1>>CCCCCCCCc1cc2cc(OC)ccc2c(Oc2ccc(C=O)cc2)c1-c1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20080207609A1,CC(C)(C)OC(=O)N1CCN(C(=O)Oc2ccc([N+](=O)[O-])cc2)CC1.CNCCOC>>COCCN(C)C(=O)N1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,,,test
US20160002213A1,S=C(n1ccnc1)n1ccnc1.[H]/N=C(/CCCN(c1cc2oc(-c3ccc(F)cc3)c(-c3ncc[nH]3)c2cc1C1CC1)S(C)(=O)=O)NO>>CS(=O)(=O)N(CCC/C(N)=N/OC(=S)n1ccnc1)c1cc2oc(-c3ccc(F)cc3)c(-c3ncc[nH]3)c2cc1C1CC1,,C1CCOC1,,CCOC(C)=O,,test
US20070042974A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCC[C@H](O)C(=O)O>>CC(C)(C)OC(=O)NCCC[C@H](O)C(=O)O,,C1COCCO1,O,CCN(CC)CC,O=C([O-])O.[Na+],test
US20110171159A1,Brc1ccc2c(c1)CCCN2.COc1ccc(CCl)cc1>>COc1ccc(CN2CCCc3cc(Br)ccc32)cc1,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20050277652A1,CCCCCC.CCN(CC)CC.CCOCC.CN(C)C(=O)Nc1cc(Oc2ccc(N)cc2)ccn1.CN(C)C=O.CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F>>CN(C)C(=O)Nc1cc(Oc2ccc(NC(=O)CC(=O)Nc3ccc(F)cc3)cc2)ccn1,,CCCCCC,,,,test
US06498251B1,CI.Cc1c(F)cccc1C(=O)O>>COC(=O)c1cccc(F)c1C,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US05807883,CCOC(=O)CCC1(NC(=O)c2ccc(Cl)c(Cl)c2)C(=O)N(CC2CO2)c2ccccc21.CSC>>CSCC(O)CN1C(=O)C(CCC(=O)O)(NC(=O)c2ccc(Cl)c(Cl)c2)c2ccccc21,,CCO,,[Na],,test
US20150218096A1,COCCBr.Cc1cc(O)cc(Cl)c1C(=O)n1nc(-c2ccc(C(=O)O)cc2F)c2ncccc21>>COCCOc1cc(C)c(C(=O)n2nc(-c3ccc(C(=O)O)cc3F)c3ncccc32)c(Cl)c1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20120022056A1,CC(C)(C)OC(=O)N1CCN(c2cccc3nc(C(F)F)ccc23)CC1>>FC(F)c1ccc2c(N3CCNCC3)cccc2n1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20090143352A1,CNC.Nc1ccc(-c2cnc3[nH]cc(-c4cccc5cc[nH]c45)c3c2)cc1C(=O)O>>CN(C)C(=O)c1cc(-c2cnc3[nH]cc(-c4cccc5cc[nH]c45)c3c2)ccc1N,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020049212A1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2.O=Cc1nc2ccccc2n1C1CCN(C2(c3ccccc3)CCCCCC2)CC1>>CC(C)(C)OC(=O)N1CC2CC1CN2Cc1nc2ccccc2n1C1CCN(C2(c3ccccc3)CCCCCC2)CC1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100009975A1,CN(C)CCN1CCSc2cc(N)ccc21.N=C(SCc1ccccc1)c1ccco1>>CN(C)CCN1CCSc2cc(NC(=N)c3ccco3)ccc21,,CCO,,Br,,test
US20040157741A1,CC(C)(C)[Si](C)(C)Cl.NS(=O)(=O)c1ccc(O)cc1>>CC(C)(C)[Si](C)(C)Oc1ccc(S(N)(=O)=O)cc1,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US20150291563A1,CS(=O)(=O)Cl.OC(C1=NN(c2cccc(N3CCNCC3)c2)C(c2ccccc2Cl)C1)(C(F)(F)F)C(F)(F)F>>CS(=O)(=O)N1CCN(c2cccc(N3N=C(C(O)(C(F)(F)F)C(F)(F)F)CC3c3ccccc3Cl)c2)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US04486438,CC(=O)Nc1nccs1.COCc1nc2c(C(F)(F)F)cccc2c(=O)o1>>COCC(=O)Nc1c(C(=O)CC(=O)Nc2nccs2)cccc1C(F)(F)F,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US20130072427A1,Cc1c(Cl)ncnc1OC1CCN(C(=O)OC(C)(C)C)CC1.Cn1ncc2c1CNC2>>Cc1c(OC2CCN(C(=O)OC(C)(C)C)CC2)ncnc1N1Cc2cnn(C)c2C1,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05354867,C=Cc1nc(CCC)n(Cc2ccc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)c1CO>>C=Cc1nc(CCC)n(Cc2ccc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)c1C=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20070281955A1,NO.O=Cc1cccc(-c2nc3sccn3c2-c2ccnc(N[C@@H]3CCCN(S(=O)(=O)c4ccc(Cl)cc4)C3)n2)c1>>O=S(=O)(c1ccc(Cl)cc1)N1CCC[C@@H](Nc2nccc(-c3c(-c4cccc(C=NO)c4)nc4sccn34)n2)C1,,CO,ClCCl,CC(=O)O,Cl,test
US20080139561A1,CC(C)Oc1cc(Nc2nc(N[C@@H](CO)c3ccc(F)cc3)c(C#N)cc2F)n[nH]1.CO>>NC(CO)(CO)c1ccc(F)cc1,[Ni],,,,,test
US06703421B1,Clc1ncnc2nc[nH]c12.NC1Cc2ccccc2C1>>c1ccc2c(c1)CC(Nc1ncnc3nc[nH]c13)C2,,CCO,,,,test
US20050171130A1,CC#CCO.CC(O)C(Cl)(Cl)Cl.Clc1cc(Cl)ncn1>>CC#CCOc1cc(OC(C)C(Cl)(Cl)Cl)ncn1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US05773388,O=C(c1ccc(Cl)cc1)c1cnc(C(F)F)nc1Cl>>OC(c1ccc(Cl)cc1)c1cnc(C(F)F)nc1Cl,,CC(C)=O,,CCO,,test
US04812463,C1=COCCC1.Cc1ccccc1S(=O)(=O)O>>OCCCCc1cccs1,,ClCCl,,,,test
US20030187023A1,C=C[Sn](CCCC)(CCCC)CCCC.CCOC(=O)CCCS(=O)(=O)c1ccc(Br)cc1>>C=Cc1ccc(S(=O)(=O)CCCC(=O)OCC)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,[Cl-].[Li+],,test
US20100204274A1,COC(=O)c1cccc(C(=O)N[C@H](C)CC(=O)N2CC[C@](O)(c3ccc(Cl)cc3)C(C)(C)C2)c1>>C[C@H](CC(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)NC(=O)c1cccc(C(=O)O)c1,,CC#N,O,O=C(O)C(F)(F)F,,test
US05516774,Cc1cc(C(=O)N2Cc3cccn3Cc3ccccc32)ccc1N.O=C(Cl)c1ccc(Cl)cc1Cl>>Cc1cc(C(=O)N2Cc3cccn3Cc3ccccc32)ccc1NC(=O)c1ccc(Cl)cc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100240678A1,CC(C)[Mg]Cl.COc1ccc(COc2cc(C#N)cc(-c3ccc4c(c3)OCO4)c2)cc1.O=S(=O)(O)O>>COc1ccc(COc2cc(C(=O)C(C)C)cc(-c3ccc4c(c3)OCO4)c2)cc1,,C1CCOC1,CCOCC,,,test
US20120077828A1,Cc1cccc(CC(=O)O)c1.Cn1nc(N)c2c(-c3ccc4c(c3)CCN4)cccc21>>Cc1cccc(CC(=O)N2CCc3cc(-c4cccc5c4c(N)nn5C)ccc32)c1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04881967,CC1Cc2c(N)ccc(Cl)c2O1.CCOC(=O)NC(=O)CC#N.O=N[O-]>>CCOC(=O)NC(=O)C(C#N)=NNc1ccc(Cl)c2c1CC(C)O2,,O,c1ccncc1,Cl,,test
US20120122780A1,CCOC(=O)CSc1c[nH]c(C)c1-c1cccc2ccccc12>>Cc1[nH]cc(SCC(=O)O)c1-c1cccc2ccccc12,,CO,,[Na+].[OH-],,test
US05614631,C#CCCCCCCCC.O=Cc1ccc2ccccc2n1>>CCCCCCCCC#Cc1ccc2nc(C=O)ccc2c1,,C1CCOC1,,CCN(CC)CC,,test
US06217793B1,CCCCCCCC[C@H](C)C(=O)Oc1ccc(OCc2ccccc2)cc1>>CCCCCCCC[C@H](C)C(=O)Oc1ccc(O)cc1,[Pd],CCOC(C)=O,,,,test
US20050119252A1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1cc(C(F)(F)F)ccc1F>>CC(C)(C)OC(=O)N1CCN(c2ccc(C(F)(F)F)cc2C=O)CC1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20080146625A1,COC(=O)C(=O)c1ccc(S(C)(=O)=O)c(Cl)c1.NOC1CCCC1>>COC(=O)/C(=N/OC1CCCC1)c1ccc(S(C)(=O)=O)c(Cl)c1,,CO,,,,test
US05284838,CC1(C)Oc2ccc(C(=O)C(F)(F)F)cc2C(O)C1Br>>CC1(C)Oc2ccc(C(=O)C(F)(F)F)cc2C2OC21,,O,,C1COCCO1,[Na+].[OH-],test
US05817700,CC1(C)C(=O)[C@@H](c2ccc(S(C)(=O)=O)cc2)[C@@H]1c1ccc(S(C)(=O)=O)cc1>>CC1(C)C(=O)C(c2ccc(S(C)(=O)=O)cc2)=C1c1ccc(S(C)(=O)=O)cc1,,c1ccccc1,,O=C1CCC(=O)N1Br,,test
US04505905,O=C(OC(c1ccccc1)c1ccccc1)C1=C(Sc2ccccc2)CC2CC(=O)C12.O=C(OO)c1cccc(Cl)c1>>O=C(OC(c1ccccc1)c1ccccc1)C1=C(S(=O)c2ccccc2)CC2CC(=O)C12,,ClCCl,,,,test
US20150005467A1,C=COC(C)COCCOCCO.CO.COC(=O)C(C)(C)N=NC(C)(C)C(=O)OC>>C=COC(C)COCCOCCO.C=COCCCCO,,CO,,,,test
US20040092737A1,CCOC(=O)C=CC1CCN(Cc2ccccc2)CC1>>CCOC(=O)C=CC1CCNCC1,,ClCCCl,,CC(Cl)OC(=O)Cl,,test
US20030055055A1,CC(=O)N1CCN(c2cccc(N)c2)CC1.CCOC(=O)c1cc([N+](=O)[O-])c(F)cc1F>>CCOC(=O)c1c(F)cc(-c2cccc(N3CCN(C(C)=O)CC3)c2)c([N+](=O)[O-])c1N,,CN1CCCC1=O,,CCN(CC)CC,O,test
US20120149573A1,CCO.ClCCl.N#Cc1ccsc1>>CCOC(=N)c1ccsc1.Cl,,CCO,ClCCl,CC(=O)Cl,,test
US20080275043A1,CC1(NC(=O)CCCCl)CCCCC1>>CC1(N2CCCC2=O)CCCCC1,,C1CCOC1,,[H-].[Na+],,test
US20070249597A1,Cc1cc(N)n(-c2ccccc2)n1.O=C1CCCCC1>>Cc1nn(-c2ccccc2)c(N)c1C1=CCCCC1,,CC(=O)O,,,,test
US20110059948A1,CN1Cc2ccccc2C(OCC2CO2)c2c1nc1ccc(Br)cc1c2Cl.c1c[nH]cn1>>CN1Cc2ccccc2C(OCC(O)Cn2ccnc2)c2c1nc1ccc(Br)cc1c2Cl,,CC(C)O,,O=C([O-])[O-].[K+].[K+],,test
US20060211678A1,CC(C)(C)N=C=O.CC(C)(C)OC(=O)N1CC=C(c2cc3c(Nc4cccc(-c5ncc[nH]5)c4)ncnc3[nH]2)CC1>>CC(C)(C)NC(=O)N1CC=C(c2cc3c(Nc4cccc(-c5ncc[nH]5)c4)ncnc3[nH]2)CC1,,CO,,CCN(CC)CC,Cl,test
US20140213578A1,NCCN1c2ccccc2Sc2ccccc21.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=S(=O)(NCCN1c2ccccc2Sc2ccccc21)c1ccc(Cl)cc1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20060199828A1,Cc1cc(NC(=O)c2nccnc2Br)ccn1.Nc1ccccc1>>Cc1cc(NC(=O)c2nccnc2Nc2ccccc2)ccn1,,C1COCCO1,,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US03971819,BrCc1ccccc1.Cc1cccc(Nc2c(N)cc(C(=O)O)cc2S(N)(=O)=O)n1>>Cc1cccc(Nc2c(NCc3ccccc3)cc(C(=O)O)cc2S(N)(=O)=O)n1,,O,,[Li+].[OH-],,test
US20120142717A1,N#CN.OCCc1ccc(Oc2ccc(F)cc2)cc1>>N=C(N)OCCc1ccc(Oc2ccc(F)cc2)cc1,,C1CCOC1,,O=S(=O)(O)C(F)(F)F,,test
US20140094445A1,COC(=O)c1ccc(Cl)c(Br)c1.NN>>NNC(=O)c1ccc(Cl)c(Br)c1,,CO,,,,test
US20120046268A1,C1CSCCN1.O=C(NC1CC(c2ccc(C(F)(F)F)cc2)CN(C(=O)Oc2ccc([N+](=O)[O-])cc2)C1)c1ccccc1>>O=C(NC1CC(c2ccc(C(F)(F)F)cc2)CN(C(=O)N2CCSCC2)C1)c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100087427A1,CC(C)c1cccc(C[C@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN(c2ccccc2)c2ccc(Cl)cc2)c1>>CC(C)c1cccc(C[C@H]2CNC[C@@H]2CN(c2ccccc2)c2ccc(Cl)cc2)c1,,C1COCCO1,Cl,,,test
US20050239802A1,CCOC(=O)c1cc(N)cc(C2=C(c3cc(C(F)(F)F)ccc3OCc3ccccc3)CCC2)c1.CI>>CCOC(=O)c1cc(NC)cc(C2=C(c3cc(C(F)(F)F)ccc3OCc3ccccc3)CCC2)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20140023611A1,Nc1ccc(N2CCCCC2)cc1C(=O)Nc1cnc(-c2cccc(C(F)(F)F)c2)cn1.O=C(O)c1cccc(C(=O)NCCOCCO)c1>>O=C(NCCOCCO)c1cccc(C(=O)NC2(N3CCCCC3)C=CC=CC2C(=O)Nc2cnc(-c3cccc(C(F)(F)F)c3)cn2)c1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120171199A1,BrCCBr.CC(C)(O)c1nc2c(Cl)nc(Cl)nc2[nH]1>>CC1(C)OCCn2c1nc1c(Cl)nc(Cl)nc12,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160002224A1,C[Si](C)(C)CCOCn1c(O[C@@H]2CO[C@@H]3[C@H](O)CO[C@H]23)cc2nc(-c3ccc(-c4ccccc4O)cc3)c(Cl)cc21>>Oc1ccccc1-c1ccc(-c2nc3cc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)cc1,,C1CCOC1,,Cl,,test
US20040023977A1,CC(C)NC(=O)CN1CCNCC1.N#Cc1cnc(Nc2cc(Cl)ncn2)s1>>CC(C)NC(=O)CN1CCN(c2cc(Nc3ncc(C#N)s3)ncn2)CC1,,CCCCO,,CCN(CC)CC,,test
US20030186984A1,CCc1cnc(Cl)nc1.CN[C@@H]1CC[C@@H](C#CCO)CC1>>CCc1cnc(N(C)[C@@H]2CC[C@@H](C#CCO)CC2)nc1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20030195354A1,COc1cc(CCN)ccc1OCc1ccccc1.O=C(Cl)Cc1ccc(Cl)cc1>>COc1cc(CCNC(=O)Cc2ccc(Cl)cc2)ccc1OCc1ccccc1,,O,,C1CCOC1,CCN(CC)CC,test
US20060189500A1,CCCCCCCC/N=C(N)/N=C(\N)NCc1ccc(Cl)c(Cl)c1>>CCCCCCCC/N=C(N)/N=C(\N)NCc1ccc(Cl)c(Cl)c1,,CO,O,Cl,[Na+].[OH-],test
US20030166639A1,CN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3ccncc3)c2)cc1-c1ccccc1F>>CN(C)c1cc2c(cc1-c1ccccc1F)NC(=O)CC(c1cccc(-c3ccncc3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080292585A1,CN(C)CCN1C(=O)c2cccc3cc4cccc(N)c4c(c23)C1=O.O=C=Nc1ccc2c(c1)OCO2>>CN(C)CCN1C(=O)c2cccc3cc4cccc(NC(=O)Nc5ccc6c(c5)OCO6)c4c(c23)C1=O,,CC#N,,CO,ClCCl,test
US05182288,COC(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3C2=O)cc1>>COC(=O)c1ccccc1-c1ccc(CN)cc1,,CCO,,NN,O,test
US20100010060A1,Nc1ccc(NCCO)cc1.O=C(Nc1cccc2c1C(=O)OC2=O)c1ccc(Cl)s1>>O=C(Nc1cccc2c1C(=O)N(c1ccc(NCCO)cc1)C2=O)c1ccc(Cl)s1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US05057614,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C1NC(=O)C(c2c[nH]c3ccccc23)=C1c1c[nH]c2ccccc12>>O=C1NC(=S)C(c2c[nH]c3ccccc23)=C1c1c[nH]c2ccccc12,,COCCOC,,,,test
US20020042411A1,CCOC(=O)c1c(Nc2ccc(OC)cc2N)sc2ccccc12.CN1CCNCC1>>COc1ccc2c(c1)N=C(N1CCN(C)CC1)c1c(sc3ccccc13)N2,Cl[Ti](Cl)(Cl)Cl,,,COc1ccccc1,,test
US20130237571A1,COc1ccc([C@H]2C[C@H]2C(=O)NC(CO)c2ccccc2)cc1>>O=C(NC(CO)c1ccccc1)[C@@H]1C[C@@H]1c1ccc(O)cc1,,ClCCl,,BrB(Br)Br,,test
US20030236296A1,CC(C)(C)OC(=O)CC(NC(=O)OCc1ccccc1)C(=O)CBr.Cc1cccc(C)c1C(=O)O>>Cc1cccc(C)c1C(=O)OCC(=O)C(CC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1,,CCOC(C)=O,CN(C)C=O,[F-].[K+],,test
US20130040929A1,O=C(CN1CCC(c2nc(-c3ccc(F)cc3)nn2-c2ncccn2)CC1)c1ccccc1>>OC(CN1CCC(c2nc(-c3ccc(F)cc3)nn2-c2ncccn2)CC1)c1ccccc1,,CCOC(C)=O,CO,[BH4-].[Na+],,test
US20080261978A1,CCOC(OCC)c1ccc(CNCCCCNC(=O)OC(C)(C)C)cc1.C[C@H](N=C=O)c1cccc2ccccc12>>CCOC(OCC)c1ccc(CN(CCCCNC(=O)OC(C)(C)C)C(=O)N[C@@H](C)c2cccc3ccccc23)cc1,,CCOC(C)=O,,CCN(CC)CC,,test
US20130090332A1,CC1(C)CN(c2ccc(Br)nc2)C(=O)N1.CI>>CN1C(=O)N(c2ccc(Br)nc2)CC1(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20140073558A1,CCCCCCCc1csc(C(=O)OCC)c1>>CCCCCCCc1csc(C(=O)O)c1,,C1CCOC1,CO,O,[Li+].[OH-],test
US09266876B2,C[Si](C)(C)CCOCCl.O=C(Cn1ccc2cccnc21)N1CCN(c2sc(Br)nc2-c2nc3ccccc3[nH]2)CC1>>C[Si](C)(C)CCOCn1c(-c2nc(Br)sc2N2CCN(C(=O)Cn3ccc4cccnc43)CC2)nc2ccccc21,,C1CCOC1,,[H-].[Na+],,test
US20130102778A1,CC#CC(=O)OCC.O/N=C(\Cl)c1ccc(Cl)cc1>>CCOC(=O)c1c(-c2ccc(Cl)cc2)noc1C,,CCOCC,,CCN(CC)CC,,test
US20100331312A1,COc1ccc(COc2ccc(CCN3CCC[C@H]3C)cc2Cl)cc1>>C[C@@H]1CCCN1CCc1ccc(O)c(Cl)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040039007A1,FC(F)(F)c1ccccc1-c1nc(Cl)cc(C2CC2)n1.Nc1n[nH]c2ncccc12>>FC(F)(F)c1ccccc1-c1nc(Nc2n[nH]c3ncccc23)cc(C2CC2)n1,,CN1CCCC1=O,,O,O=C([O-])O.[Na+],test
US20080166359A1,CC(C)c1cc(C(C)C)c(S(=O)(=O)OC(CC2OCCO2)C2(O)CN(C(=O)c3ccc(F)c(F)c3Nc3ccc(I)cc3F)C2)c(C(C)C)c1>>O=C(c1ccc(F)c(F)c1Nc1ccc(I)cc1F)N1CC2(C1)OC2CC1OCCO1,,C1CCOC1,,CCOC(C)=O,[H-].[Na+],test
US04816452,CCOC(=O)/C(=N\OC(C)(C)[C@@H]1CC[C@@H](C)CC1)c1csc(N)n1>>C[C@@H]1CC[C@@H](C(C)(C)O/N=C(\C(=O)O)c2csc(N)n2)CC1,,CCO,O,[Na+].[OH-],,test
US20050208582A1,CCOC(=O)c1ccc2c(c(/C=C/c3ccc(F)cc3)nn2C(=O)OC(C)(C)C)c1OCCOC1CCCCO1>>CCOC(=O)c1ccc2c(c(/C=C/c3ccc(F)cc3)nn2C(=O)OC(C)(C)C)c1OCCO,,C1CCOC1,,Cl,O,test
US20070032522A1,CN1CCN(c2cc3c(cc2F)c(=O)c(N)cn3Cc2ccc(Cl)cc2)CC1.O=C=Nc1ccc(Cl)cc1>>CN1CCN(c2cc3c(cc2F)c(=O)c(NC(=O)Nc2ccc(Cl)cc2)cn3Cc2ccc(Cl)cc2)CC1,,CN(C)C=O,,CCN(CC)CC,O,test
US05681839,COc1ccc(CC2CCC3NC(=O)C(CO)CC3C2)cc1>>O=C1NC2CCC(Cc3ccc(O)cc3)CC2CC1CO,,ClCCl,,BrB(Br)Br,,test
US20100152045A1,CC(C)(C)OC(=O)CCl.Oc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl>>CC(C)(C)OC(=O)COc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20080090873A1,CC#N.CC(C)(C)[Si](C)(C)O[C@@H](CBr)c1ccc(OCc2ccccc2)c(NS(C)(=O)=O)c1.NCCCCCCCCCN1CCC(N(C(=O)[O-])c2ccc(F)cc2-c2ccc(OCc3ccccc3)c(Cl)c2)CC1>>CC(C)(C)[Si](C)(C)O[C@@H](CNCCCCCCCCCN1CCC(N(C(=O)[O-])c2ccc(F)cc2-c2ccc(OCc3ccccc3)c(Cl)c2)CC1)c1ccc(OCc2ccccc2)c(NS(C)(=O)=O)c1.N,,CCOC(C)=O,,O=C([O-])O.[Na+],,test
US20070059249A1,COC(=O)Cl.C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2O>>COC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C,,c1ccncc1,,,,test
US20090270389A1,CCOC(=O)c1cnc(SC)nc1NC1CCCC1>>CSc1ncc(C(=O)O)c(NC2CCCC2)n1,,CCO,,Cl,[Na+].[OH-],test
US20150045323A1,CCCO.COc1cc2ncnc(Cl)c2cc1I.COc1cc2ncnc(Nc3ccc4scnc4c3)c2cc1I.Nc1ccc2scnc2c1>>COc1cc2ncnc(Nc3ccc4scnc4c3)c2cc1SC(C)(C)C,,CCCO,,,,test
US20110190269A1,CC(C)(C)[Si](C)(C)OCCCc1ccccc1.O=C1CCC(=O)N1Br>>CC(C)(C)[Si](C)(C)OCCC(Br)c1ccccc1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US04435322,CCOC(=O)CCN1C(=O)CC1C(=O)OCC>>CCOC(=O)CCN1C(=O)CC1CO,,CCO,,,,test
US20150336979A1,CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2[C@@H](NCc3ccccc3)CO[C@@H]21>>CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2[C@@H](N)CO[C@@H]21,[Pd],CO,,,,test
US20080096895A1,Nc1cc(Br)cnc1N.O=C(O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1>>O=C(c1ccccc1C(F)(F)F)N1CCN(c2ccc(-c3nc4cc(Br)cnc4[nH]3)nn2)CC1,,O=P(Cl)(Cl)Cl,,,,test
US20070299071A1,OC1(c2ccc(C(F)(F)F)cc2)CCNC1>>FC(F)(F)c1ccc(C2=CCNC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100022516A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.CCc1cccc(CC)c1-c1nc(C)c(COc2cc(C(C)C)ccc2C)c(Cl)n1>>CCc1cccc(CC)c1-c1nc(C)c(COc2cc(C(C)C)ccc2C)c(C2=CCN(C(=O)OC(C)(C)C)CC2)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06200976B1,N#Cc1ccc(CN)cc1.Nc1cc([N+](=O)[O-])ccc1C(=O)O>>N#Cc1ccc(CNC(=O)c2ccc([N+](=O)[O-])cc2N)cc1,,CN(C)C=O,,,,test
US06559155B1,CCCCCCCCCCCCN(C)C(=O)Cn1cc(Cc2cnc(=O)n(CC(=O)OCC)c2)c(=O)nc1SCc1ccc(F)cc1>>CCCCCCCCCCCCN(C)C(=O)Cn1cc(Cc2cnc(=O)n(CC(=O)O)c2)c(=O)nc1SCc1ccc(F)cc1,,C1COCCO1,O,[Na+].[OH-],,test
US05017211,CCN(CC)C(=O)c1cc(N)c(F)cc1Cl.O=C(Cl)OC(Cl)(Cl)Cl>>CCN(CC)C(=O)c1cc(N=C=O)c(F)cc1Cl,,CCOC(C)=O,,,,test
US20120214803A1,Nc1ccc(N2CCOCC2)c2cccnc12.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=[N+]([O-])c1ccccc1S(=O)(=O)Nc1ccc(N2CCOCC2)c2cccnc12,,c1ccncc1,,,,test
US20100063104A1,COC(=O)C1(C(=O)OC)CCOCC1>>COC(=O)C1(CO)CCOCC1,,C1CCOC1,,O=S(=O)([O-])[O-].[Na+].[Na+],,test
US20090018122A1,CCOCc1nc2cnc3ccc(OCc4ccccc4)cc3c2n1CC(C)(C)N.O=C(Cl)C1CCCCC1>>CCOCc1nc2cnc3ccc(OCc4ccccc4)cc3c2n1CC(C)(C)NC(=O)C1CCCCC1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20150266857A1,Nc1nc2ccc(-c3cn(S(=O)(=O)c4ccccc4)c4cc(F)ccc34)cc2o1>>Nc1nc2ccc(-c3c[nH]c4cc(F)ccc34)cc2o1,,CO,,[Cl-].[NH4+],,test
US07105517B2,CN1CCNCC1.CS(=O)c1nccc(-c2sc(Cl)nc2-c2ccccc2)n1>>CN1CCN(c2nc(-c3ccccc3)c(-c3ccnc(S(C)=O)n3)s2)CC1,,C1CCOC1,O,,,test
US20040044004A1,CCOC(=O)C1CN(Cc2ccccc2)CCN1Cc1ccccc1>>CCOC(=O)C1CNCCN1,[Pd],CCO,,,,test
US20110201643A1,COC(=O)c1ccc2c(c1)CN(Cc1ccccc1)C2.O=C(Cl)OCc1ccccc1>>COC(=O)c1ccc2c(c1)CN(C(=O)OCc1ccccc1)C2,,ClCCl,,O,O=C([O-])O.[Na+],test
US05166347,CC(C)OC(=NC#N)c1cccnc1.NCC(c1ccccc1)c1ccccc1>>N#CNC(=NCC(c1ccccc1)c1ccccc1)c1cccnc1,,CO,,,,test
US06132696,Cl.NCCO.NCCO.[Cl-]>>Cl.NCCO.NCCO.[Cl-],,O,,,,test
US20140274930A1,CCCCP(CCCC)CCCC.COC(=O)CBr>>CCCCP(=CC(=O)OC)(CCCC)CCCC,,Cc1ccccc1,,,,test
US20100029626A1,CCOC(=O)c1nccc(Oc2ccc3c(C(=O)Nc4ccc(F)c(C(F)(F)F)c4)cccc3c2)n1>>O=C(Nc1ccc(F)c(C(F)(F)F)c1)c1cccc2cc(Oc3ccnc(CO)n3)ccc12,,CC(C)(C)O,,[BH4-].[Na+],,test
US04173707,CCC#CCC1(C(=O)OC(C)(C)C)C(=O)C=CC1CC(=O)OC.CO>>CCC#CCC1(C(=O)OC)C(O)CCC1CC(=O)OC,,CO,,CC(=O)O,[BH4-].[Na+],test
US20140249126A1,CCn1cc(C(=O)OCc2ccc(OC)cc2)c(=O)c2c(Cl)c(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)cc21>>CCn1cc(C(=O)O)c(=O)c2c(Cl)c(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)cc21,,CO,O,[K+].[OH-],,test
US20110065681A1,N#Cc1ccc2cc(C(=O)O)sc2c1>>N#Cc1ccc2ccsc2c1,,CC(=O)N(C)C,,C1CCC2=NCCCN2CC1,Cl,test
US20070027158A1,CCCn1c(CCl)nc2cccnc21.COc1ccc(CN)cc1>>CCCn1c(CNCc2ccc(OC)cc2)nc2cccnc21,,CC#N,,,,test
US20090118282A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1cc(CN2CCCCC2)ccc1O>>CC(C)(C)OC(=O)Nc1cc(CN2CCCCC2)ccc1O,[Pd],CO,,,,test
US20150111870A1,COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1O.OCCN1CCOCC1>>COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1OCCN1CCOCC1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090118296A1,CC(C)(C)C(=O)NNC(=O)c1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CC(C)(C)c1nnc(-c2ccc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)nn2)s1,,C1CCOC1,,,,test
US05576321,Brc1cccc(N2CCNCC2)c1.O=C(O)C(=O)O.c1cc(OC[C@@H]2CO2)c2cc[nH]c2c1>>O=C(O)C(=O)O.O[C@H](COc1cccc2[nH]ccc12)CN1CCN(c2cccc(Br)c2)CC1,,CCOC(C)=O,,CO,,test
US20120225844A1,CCOC(=O)C(=O)CC(=O)C(C)Oc1ccccc1.NN>>CCOC(=O)c1cc(C(C)Oc2ccccc2)n[nH]1,,CCO,,O,,test
US20090264445A1,CCOC(=O)C=C(C)Cl.Oc1ccccc1OCc1ccccc1>>CCOC(=O)/C=C(\C)Oc1ccccc1OCc1ccccc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20160264575A1,O=C(n1ccnc1)n1ccnc1.OC[C@@H]1Cc2c(n(Cc3ccc(F)cc3)c3ccccc23)CN1>>O=C1OC[C@@H]2Cc3c(n(Cc4ccc(F)cc4)c4ccccc34)CN12,CN(C)c1ccncc1,C1CCOC1,O,CCN(CC)CC,,test
US03992333,C=CC(=O)OCCN(CO)C(N)=O.C=CC(=O)OCCO.CCOC(C)=O>>C=C(C)C(=O)OCCO.C=CC(=O)OCCN(CO)C(N)=O,,CCOC(C)=O,,[Na],,test
US04898867,CCCCCCn1c(=O)[nH]c2sc3c(c2c1=O)CCCC3.CCOC(=O)CBr>>CCCCCCn1c(=O)c2c3c(sc2n(CC(=O)OCC)c1=O)CCCC3,,ClC(Cl)Cl,,[H-].[Na+],,test
US20110166146A1,CC1=CNC(C)(N)C=C1.Cc1ccc(C(=O)CBr)cc1>>Cc1ccc(-c2cn3cc(C)ccc3n2)cc1,,CCO,,CCOCC,O=C([O-])[O-].[K+].[K+],test
US20150299189A1,BrCc1ccccc1.O=c1[nH]c2ccc(Br)cc2o1>>O=c1oc2cc(Br)ccc2n1Cc1ccccc1,,C1CCOC1,CCOC(C)=O,O,CC(C)(C)[O-].[K+],test
US20160075663A1,CN[C@H](C)C(=O)Nc1nc2ccc(C#N)cc2n1C1CCC1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>C[C@H](C(=O)Nc1nc2ccc(C#N)cc2n1C1CCC1)N(C)CC(F)(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20110183979A1,COCc1ccc(Br)c(C#N)n1.O.[OH-]>>COCc1ccc(Br)c(C(=O)O)n1,,O,,CO,,test
US20110183997A1,CC(=O)C1CC1.CSC(=S)SC>>CSC(=CC(=O)C1CC1)SC,,CN(C)C=O,,[H-].[Na+],,test
US20020052512A1,COC(=O)[C@@H](N)CNC(=O)c1ccccc1.O=C(NCc1cccc2[nH]ccc12)c1ccc(C(=O)O)c(Cl)c1>>COC(=O)[C@H](CNC(=O)c1ccccc1)NC(=O)c1ccc(C(=O)NCc2cccc3[nH]ccc23)cc1Cl,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US05102667,O=C(O)Cc1ccccc1N1CCOCC1.O=C1CCC(c2ccccc2)(c2ccccc2)C2CNCC12>>O=C1CCC(c2ccccc2)(c2ccccc2)C2CN(C(=O)Cc3ccccc3N3CCOCC3)CC12,,ClCCl,,CCN(CC)CC,Cl,test
US20040010007A1,CC(C)(C)OC(=O)NCCOCCN.Cc1nc(Cl)c([N+](=O)[O-])c(Cl)c1C>>Cc1nc(Cl)c([N+](=O)[O-])c(NCCOCCNC(=O)OC(C)(C)C)c1C,,CN(C)C=O,,CCN(CC)CC,,test
US05604224,COc1cccc2c[n+]3ccsc3cc12.[O-][Cl+3]([O-])([O-])[O-]>>Oc1cccc2c[n+]3ccsc3cc12.[O-][Cl+3]([O-])([O-])[O-],,Br,,,,test
US06403534B1,CCOC(=O)C(CCBr)Oc1cc([N+](=O)[O-])c(F)cc1Cl>>CCOC(=O)C1(Oc2cc([N+](=O)[O-])c(F)cc2Cl)CC1,,C1CCOC1,,Cl,CC(C)(C)[O-].[K+],test
US20120122911A1,CC(C)(C)OC(=O)c1cnc2c(c1)C[C@@]1(C2)C(=O)Nc2ncnc(Cl)c21.CCOC(C)=O>>CCCCOC(=O)c1cnc2c(c1)C[C@@]1(C2)C(=O)Nc2ncncc21,[Pd],,,CCN(CC)CC,[H][H],test
US05596124,ClCCl.O=C(Cl)C(=O)Cl.O=C(O)COc1ccc(Oc2ccc(C(F)(F)F)c(Cl)c2)cc1C(=O)O>>O=C(Cl)COc1ccc(Oc2ccc(C(F)(F)F)c(Cl)c2)cc1C(=O)Cl,CN(C)C=O,Cc1ccccc1,,,,test
US20100075944A1,C1CCOC1.CCN(CC)CC.Nc1cc(Oc2ccc([N+](=O)[O-])cc2)ccn1.O=C(Cl)Oc1ccccc1>>O=C(Nc1cc(Oc2ccc([N+](=O)[O-])cc2)ccn1)N1CCCC1,,C1CCOC1,,,,test
US20030022881A1,CCCC[Sn](CCCC)(CCCC)c1cn2cnc(SC)c2s1.O=C1CCC(=O)N1I>>CSc1ncn2cc(I)sc12,,C1CCOC1,,CCOC(C)=O,,test
US05449812,COC(=O)c1ccc(N(C)C(=O)OC)cc1S(N)(=O)=O.O=C(Cl)Cl>>COC(=O)c1ccc(N(C)C(=O)OC)cc1S(=O)(=O)N=C=O,,ClCCCl,,O=S(Cl)Cl,c1ccncc1,test
US20120252801A1,CCC1(CC)CO1.CCN>>CCNCC(O)(CC)CC,,CO,O,,,test
US20040220404A1,CN1CCC[C@H]1CO.COc1cc([N+](=O)[O-])ccc1Cl>>COc1cc([N+](=O)[O-])ccc1OC[C@@H]1CCCN1C,,CN(C)C=O,,[H-].[Na+],,test
US20060258690A1,CC(C)(C)OC(=O)N1CCC2(CCNCC2)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC2(CCN(S(C)(=O)=O)CC2)C1,,CCN(CC)CC,ClCCl,,,test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cccnc3Nc3ccc(NC(=O)NC(C)C)nc3)n2)cc1>>Cc1nc(N)nc(-c2cccnc2Nc2ccc(NC(=O)NC(C)C)nc2)n1,,O=C(O)C(F)(F)F,,O=S(=O)(O)C(F)(F)F,,test
US20140364398A1,CCOC(=O)C(C)(CCc1ccc(N)cc1)S(C)(=O)=O.O=Cc1ccccc1[N+](=O)[O-]>>CCOC(=O)C(C)(CCc1ccc(/N=C/c2ccccc2[N+](=O)[O-])cc1)S(C)(=O)=O,,CCO,,,,test
US20070225372A1,CCOC(=O)C1C2CCC(C2COC)N1C(=O)OC(C)(C)C>>COCC1C2CCC1N(C(=O)OC(C)(C)C)C2CO,,ClCCl,,,,test
US05525619,COCCn1nc(-c2ccc(O)cc2)oc1=O.CS(=O)(=O)OCC1CCCOC1>>COCCn1nc(-c2ccc(OCC3CCCOC3)cc2)oc1=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20020193616A1,CCC(/C=C/CO[C@H](C)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C)(CC)O[Si](CC)(CC)CC>>CCC(O)(/C=C/CO[C@H](C)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C)CC,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040171655A1,CC(=Cc1ccc(F)cc1F)CNC1CCN(C(=O)OC(C)(C)C)C1.COc1ccc(C(=O)O)cc1OC>>COc1ccc(C(=O)N(CC(C)=Cc2ccc(F)cc2F)C2CCNC2)cc1OC,,CCN(CC)CC,,O=S(Cl)Cl,,test
US05489586,COC(=O)c1sc2ccc(OC)cc2c1O.N#CCBr>>COC(=O)c1sc2ccc(OC)cc2c1OCC#N,,CCOC(C)=O,CS(C)=O,Cl,CC(C)(C)[O-].[K+],test
US20140296225A1,CCOC(=O)CNCCN(CCc1ccc([N+](=O)[O-])cc1)C(=O)OC(C)(C)C>>O=C1CNCCN1CCc1ccc([N+](=O)[O-])cc1,,C1COCCO1,,CCN(CC)CC,Cl,test
US20140343000A1,C=C(C)[C@@H]1CC[C@]2(NCCN3CCN(C(=O)OC(C)(C)C)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.Cl>>C=C(C)[C@@H]1CC[C@]2(NCCN3CCNCC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.Cl,,C1CCOC1,,,,test
US20110306606A1,CCCCc1ccc(N)cc1.O=[N+]([O-])c1ccc(Cl)nc1Cl>>CCCCc1ccc(Nc2nc(Cl)ccc2[N+](=O)[O-])cc1,,O,,CCN(CC)CC,CO,test
US20090036446A1,CC(C)(C)[Si](C)(C)OCCc1cc2ccccc2n1-c1ccc(OCc2ccccc2)cc1>>OCCc1cc2ccccc2n1-c1ccc(OCc2ccccc2)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140045936A1,CN.COC(=O)C1(c2ccc(Cl)c(Cl)c2)CC1C=O>>CNCC1CC1(C(=O)OC)c1ccc(Cl)c(Cl)c1,,CO,,[BH4-].[Na+],,test
US20140275043A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCC1CCSCC1>>Cc1ccc(S(=O)(=O)OCC2CCSCC2)cc1,,ClCCl,O,c1ccncc1,,test
US20070049593A1,COC(=O)c1ccc2c(C3CCCCC3)c(Br)n(CCN3C(=O)c4ccccc4C3=O)c2c1>>COC(=O)c1ccc2c(C3CCCCC3)c(Br)n(CCN)c2c1,,C1CCOC1,CO,NN,O,test
US20150111885A1,COC(=O)c1cc2c(Br)cn(C)c(=O)c2s1.N>>Cn1cc(Br)c2cc(C(N)=O)sc2c1=O,,CO,,,,test
US20120022041A1,O/N=C/c1ccccn1.O=C1CCC(=O)N1Cl>>ON=C(Cl)c1ccccn1,,CN(C)C=O,,O,,test
US05420164,CC(C)c1cccc(C(C)C)c1N=C=O.c1ccc(CN[C@H]2CC[C@@H](c3ccccc3)CC2)cc1>>CC(C)c1cccc(C(C)C)c1NC(=O)N(Cc1ccccc1)[C@@H]1CC[C@H](c2ccccc2)CC1,,ClCCl,,Cl,c1ccncc1,test
US20140303142A1,CC(C)C(Nc1cncc(Br)c1)C(=O)NCC(F)(F)F.COC(=O)CCS(=O)(=O)c1cnc2c(c1)c(B1OC(C)(C)C(C)(C)O1)cn2COCC[Si](C)(C)C>>COC(=O)CCS(=O)(=O)c1cnc2c(c1)c(-c1cncc(NC(C(=O)NCC(F)(F)F)C(C)C)c1)cn2COCC[Si](C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US20140275172A1,CCOC(=O)CCc1ccc(O)c(C)c1C.Cc1c(CCC(=O)O)ccc(OCc2cc(Cl)cc3cn(C)nc23)c1C>>CCOC(=O)CCc1ccc(OCc2cc(Cl)cc3cnn(C)c23)c(C)c1C,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05274116,O=C(N[C@@H](CO)C(=O)Nn1cccc1)OCc1ccccc1>>N[C@@H](CO)C(=O)Nn1cccc1,[Pd],CO,,,,test
US20100305145A1,CCOC(=O)[C@H](C)C[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)c1cc(F)c(O)c(F)c1>>C[C@H](C[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)c1cc(F)c(O)c(F)c1)C(=O)O,,CO,,Cl,[Na+].[OH-],test
US20060079533A1,CN1CCC(c2ccc(Cl)cc2)C(OCc2ccc3ccccc3c2)C1.O=C(Cl)OCC(Cl)(Cl)Cl>>O=C(OCC(Cl)(Cl)Cl)N1CCC(c2ccc(Cl)cc2)C(OCc2ccc3ccccc3c2)C1,,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20120035134A1,CCN(CCOP(=O)(OC(C)(C)C)OC(C)(C)C)CC[C@H](CSc1ccccc1)Nc1ccc(S(=O)(=O)NC(=O)c2ccc(N3CCC([C@@H](O)c4ccccc4-c4ccc(Cl)cc4)CC3)cc2)cc1S(=O)(=O)C(F)(F)F.Cl>>CCN(CCOP(=O)(O)O)CC[C@H](CSc1ccccc1)Nc1ccc(S(=O)(=O)NC(=O)c2ccc(N3CCC([C@@H](O)c4ccccc4-c4ccc(Cl)cc4)CC3)cc2)cc1S(=O)(=O)C(F)(F)F.Cl,,CO,ClCCl,,,test
US20110269741A1,CCOC(=O)c1cn([C@@H](C(C)(C)C)C(C)(C)O[SiH2]C(C)(C)C)c2cc(F)c(C#Cc3ccc(F)cc3F)cc2c1=O>>CCOC(=O)c1cn([C@@H](C(C)(C)C)C(C)(C)O[SiH2]C(C)(C)C)c2cc(F)c(CCc3ccc(F)cc3F)cc2c1=O,[Pd],CO,,,,test
US05395846,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.NC1C2CC3CC1CC(O)(C3)C2>>OC12CC3CC(C1)C(NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(C3)C2,,ClCCl,,CCN(CC)CC,,test
US20160212997A1,COC(CN)OC.ClCc1ccc(Cl)nc1>>COC(CNCc1ccc(Cl)nc1)OC,,CC#N,,CCN(CC)CC,,test
US20160129002A1,CC(C)[Mg]Cl.O=Cc1cc(COCC(F)(F)F)nc(Cl)n1>>CC(C)C(O)c1cc(COCC(F)(F)F)nc(Cl)n1,,CCOCC,,,,test
US20130029980A1,Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CC(N)Cc3ccccc3)c2cc1C.O=Cc1ccccc1>>Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CC(Cc3ccccc3)NCc3ccccc3)c2cc1C,CC(=O)O,CO,,[BH3-]C#N.[Na+],,test
US20060160794A1,C=N/C(C(=O)OC)=C(\Br)c1ccccc1.NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>COC(=O)c1ncn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-c1ccccc1,,CN(C)C=O,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20160031903A1,CCOC(=O)C(C)(C(=O)OCC)c1nc(-c2cc(-c3ccon3)n(Cc3ccccc3F)n2)ncc1[N+](=O)[O-]>>CCOC(=O)C(C)(C(=O)OCC)c1nc(-c2cc(-c3ccon3)n(Cc3ccccc3F)n2)ncc1N,[Pd],CCO,CCOC(C)=O,[H][H],,test
US20110150833A1,CN(C)C(=O)COc1cc(Br)ccc1[N+](=O)[O-]>>CN(C)C(=O)COc1cc(Br)ccc1N,,CCO,,,,test
US20110118230A1,COc1ccc(NC(=O)OC(C)(C)C)cn1.ClCCI>>COc1cc(I)c(NC(=O)OC(C)(C)C)cn1,,CCOCC,,CN(C)CCN(C)C,[Li]CCCC,test
US20020013460A1,C#Cc1ccccc1OC.COc1ccc(Br)c(C=O)c1>>COc1ccc(C#Cc2ccccc2OC)c(C=O)c1,,CN(C)C=O,,CCN(CC)CC,,test
US20120202785A1,COC(=O)c1c(F)ccc2nc([C@H](C)Nc3ncnc4c3ncn4C3CCCCO3)n(C3CC3)c12>>COC(=O)c1c(F)ccc2nc([C@H](C)Nc3ncnc4[nH]cnc34)n(C3CC3)c12,,ClCCl,,,,test
US20150183802A1,COC(=O)C(C)=Cc1ccc(F)c(OC)c1>>COc1cc(C=C(C)C(=O)O)ccc1F,,CO,,Cl,[Na+].[OH-],test
US20080004302A1,CN(C)Cc1ccc(CCc2cc(N)n[nH]2)o1.Cc1cc(CNc2nccc(Cl)n2)on1>>Cc1cc(CNc2nccc(Nc3cc(CCc4ccc(CN(C)C)o4)[nH]n3)n2)on1,,CCO,,Cl,,test
US20060252751A1,O=C(CNC(=O)c1cccc(C(F)(F)F)c1)N[C@@H]1CCNC1.O=C1CCC(O)(c2ccc(N3CCC3)nc2)CC1>>O=C(CNC(=O)c1cccc(C(F)(F)F)c1)N[C@@H]1CCN(C2CCC(O)(c3ccc(N4CCC4)nc3)CC2)C1,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US04332820,N#Cc1cc([N+](=O)[O-])ccc1Cl.Oc1ccc(Cl)cc1Cl>>N#Cc1cc([N+](=O)[O-])ccc1Oc1ccc(Cl)cc1Cl,,CS(C)=O,,O,[Na+].[OH-],test
US20150336986A1,C[C@@H](Cn1cc2c(c1-c1ccccc1)c(=O)n(C)c(=O)n2C)SC(c1ccccc1)(c1ccccc1)c1ccccc1>>C[C@H](S)Cn1cc2c(c1-c1ccccc1)c(=O)n(C)c(=O)n2C,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20110301143A1,CC(C)(C)OC(=O)Cn1nnc(-c2cnc(N3CC=C(c4cccc(Cl)c4)CC3)s2)n1>>O=C(O)Cn1nnc(-c2cnc(N3CC=C(c4cccc(Cl)c4)CC3)s2)n1,,O,,O=CO,,test
US20030114437A1,CCCN1C[C@H](O)[C@@H](NC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccco2)CC[C@H]1C>>CCCN1CC(=O)[C@@H](NC(=O)[C@H](CC2CCCCC2)NC(=O)c2ccco2)CC[C@H]1C,,CS(C)=O,O,CCN(CC)CC,,test
US20130079478A1,CC=O.Cc1cccc(C)c1N>>CC=Nc1c(C)cccc1C,,C1CCOC1,,,,test
US20060041129A1,CCCC(=O)Nc1snc(C)c1C(N)=O>>CCCc1nc2snc(C)c2c(=O)[nH]1,,N,,,,test
US04638068,CC(C)C(C)(C#N)N1C(=O)C=C(Br)C1=O.Nc1ccccc1CO>>CC(C)C(C)(C#N)N1C(=O)C=C(Nc2ccccc2CO)C1=O,,CCO,,,,test
US20090054405A1,Clc1nc2ccc(Br)cc2s1.NCC1CCCCC1>>Brc1ccc2nc(NCC3CCCCC3)sc2c1,,CN(C)C=O,,CCN(CC)CC,,test
US04264599,BrCCOC1CCCCO1.O=C(OCc1ccccc1)N1CCC(N2CCNC2=O)CC1>>O=C(OCc1ccccc1)N1CCC(N2CCN(CCOC3CCCCO3)C2=O)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20160264518A1,COC(=O)/C=C/c1ccccc1N.N#Cc1cccc(CBr)c1>>COC(=O)/C=C/c1ccccc1NCc1cccc(C#N)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20110086834A1,CI.O=C1NCCC(=O)c2c1[nH]c1ccc(Br)cc21>>Cn1c2c(c3cc(Br)ccc31)C(=O)CCNC2=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080090818A1,Brc1csc(Br)n1.CCOC(=O)OCC>>CCOC(=O)c1nc(Br)cs1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US06150362,Br[Mg]c1ccc(-c2ccccc2)cc1.Clc1nc(Cl)nc(Cl)n1>>Clc1nc(Cl)nc(-c2ccc(-c3ccccc3)cc2)n1,,c1ccccc1,,,,test
US04290964,CCC1CCCCCCCCC(C)(C)C=N1.O=S(=O)(O)O>>CCC(N)CCCCCCCCC(C)(C)C(=O)O,,O,,[Na+].[OH-],,test
US20050070592A1,CCCCCCC(=O)c1ccccc1.NNc1ccc(Br)cc1>>CCCCCc1c(-c2ccccc2)[nH]c2ccc(Br)cc12,,CCO,,Cl,,test
US20150291595A1,COc1cccc(CNC(=O)c2c(Cl)ncnc2Cl)c1.N>>COc1cccc(CNC(=O)c2c(N)ncnc2Cl)c1,,C1COCCO1,,,,test
US20140171423A1,O=C(Cl)c1cccc(C(F)(F)F)c1.O=C1CCNC[C@H]2C[C@H](Oc3cnc(C4CC4)cn3)CN12>>O=C(c1cccc(C(F)(F)F)c1)N1CCC(=O)N2C[C@@H](Oc3cnc(C4CC4)cn3)C[C@@H]2C1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,Cl,test
US04801605,CCOC(=O)CSc1cccc(OC(C)=O)c1CC(=O)OCC>>CCOC(=O)CSc1cccc(O)c1CC(=O)OCC,,CCO,,N,,test
US20060142336A1,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.OC1CCNCC1>>CC(C)(C)[Si](C)(C)OC1CCNCC1,,ClCCl,,O,c1ccncc1,test
US20150232481A1,C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(CI)nn23)CC1.C=CCc1cc(F)ccc1CO>>C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(COCc4ccc(F)cc4CC=C)nn23)CC1,,CN(C)C=O,,[H-].[Na+],,test
US05399574,CN1CCC(=O)CC1.O=[N+]([O-])CCc1ccc2[nH]ccc2c1>>CN1CC=C(c2c[nH]c3ccc(CC[N+](=O)[O-])cc23)CC1,,CC(=O)O,,[NH4+].[OH-],,test
US20050124637A1,CC(=O)c1ccc(Nc2nc(F)nc3c2ncn3C2CCCCO2)cc1.CNC1CCN(C)CC1>>CC(=O)c1ccc(Nc2nc(N(C)C3CCN(C)CC3)nc3c2ncn3C2CCCCO2)cc1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US04468245,C=CCN(C(C)c1ccccc1)S(=O)(=O)c1ccc(CCC)cc1.O=C(OO)c1cccc(Cl)c1>>CCCc1ccc(S(=O)(=O)N(CC2CO2)C(C)c2ccccc2)cc1,,ClC(Cl)Cl,,O=S([O-])[O-].[Na+].[Na+],,test
US20050148623A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H](C[C@H](Cc1ccc(Br)cc1)NC(=O)OCc1ccccc1)O[Si](C)(C)C(C)(C)C.CCCC[Sn](CCCC)(CCCC)c1ccncc1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H](C[C@H](Cc1ccc(-c2ccncc2)cc1)NC(=O)OCc1ccccc1)O[Si](C)(C)C(C)(C)C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,[Cl-].[Li+],,test
US20150164974A1,C[C@@H](C(=O)N[C@@H](Cc1ccc(N)cc1)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)N(C)C(=O)OC(C)(C)C.C[C@@H](C(=O)N[C@H](C(=O)N1C[C@@H](N)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C)N(C)C(=O)OC(C)(C)C.O=C(Cl)Cl>>CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(NC(=O)N[C@H]2C[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C2)cc1)C(=O)N1C[Si](C)(C)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05128356,CCCCC(=O)Cl.COC(=O)c1cc(Cl)ccc1N>>CCCCC(=O)Nc1ccc(Cl)cc1C(=O)OC,,ClCCl,,CCN(CC)CC,,test
US20090029994A1,CC(C)(C)OC(=O)CCCBr.COc1ccc(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CN(Cc1cc(C#N)cc(C(F)(F)F)c1)c1ccc(O)cn1>>COc1ccc(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CN(Cc1cc(C#N)cc(C(F)(F)F)c1)c1ccc(OCCCC(=O)OC(C)(C)C)cn1,,CN(C)C=O,,O,[H-].[Na+],test
US20160046618A1,COC[C@]12C[C@H]1[C@@](C)(c1cc(N)cnc1F)N=C(N(COCC[Si](C)(C)C)C(=O)OC(C)(C)C)S2.Clc1cnc2c(Cl)ncnc2c1>>COC[C@]12C[C@H]1[C@@](C)(c1cc(Nc3ncnc4cc(Cl)cnc34)cnc1F)N=C(N)S2,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20110218192A1,O=C(C=Cc1ccccc1)c1cc(Br)c(F)cc1O>>O=C1CC(c2ccccc2)Oc2cc(F)c(Br)cc21,,CCO,O,[Na+].[OH-],,test
US20160159752A1,CC(C)(C)OC(=O)N1[C@@H](CCc2c(F)cccc2NC(=O)C(OCc2ccccc2)C(c2ccccc2)c2ccccc2)COC1(C)C>>N[C@H](CO)CCc1c(F)cccc1NC(=O)C(OCc1ccccc1)C(c1ccccc1)c1ccccc1,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20120329780A1,CN1CCN(C(=O)c2ccc(N)cc2)CC1.COc1ccc(Cn2cc3nc(-c4cccs4)nc(Cl)c3n2)cc1>>CN1CCN(C(=O)c2ccc(Nc3nc(-c4cccs4)nc4cn[nH]c34)cc2)CC1,C1COCCO1,CO,,Cl,,test
US20090105306A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)c1nnc(N)s1>>CC(C)(C)OC(=O)Nc1nnc(C(C)(C)C)s1,,ClCCl,,,,test
US20020147333A1,C#C[Sn](CCCC)(CCCC)CCCC.CN1NOC(=O)C1Cc1ccccc1>>CCCC[Sn](CCCC)(CCCC)c1cc(Cc2ccccc2)n(C)n1,,Cc1ccccc1C,,,,test
US20130210768A1,CCCC[Sn](CCCC)(CCCC)c1cccnc1F.Cn1c(=O)n(CC(C)(C)C)c2ccc(Cl)nc21>>Cn1c(=O)n(CC(C)(C)C)c2ccc(-c3cccnc3F)nc21,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,,,,,test
US20160102081A1,CC1(C)OB(c2cc3cc(N)ccc3s2)OC1(C)C.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>CC1(C)OB(c2cc3cc(NC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)ccc3s2)OC1(C)C,,C1CCOC1,CCOC(C)=O,,,test
US20100099677A1,CC(C)(C)C(=O)Cl.O=C(c1nc(-c2cc(Br)c(O)c(Br)c2O)cs1)N1CCC(Cc2ccccc2)CC1>>CC(C)(C)C(=O)Oc1c(Br)cc(-c2csc(C(=O)N3CCC(Cc4ccccc4)CC3)n2)c(O)c1Br,,ClCCl,,c1ccncc1,,test
US04579847,Nc1ccc2c(=O)n3c(nc2c1)C(=Cc1ccccc1)CC3.O=C1OC(=O)C(Cl)=C1Cl>>O=C(O)/C(Cl)=C(/Cl)C(=O)Nc1ccc2c(=O)n3c(nc2c1)C(=Cc1ccccc1)CC3,,C1CCOC1,,,,test
US20040063680A1,CC(C)S(=O)(=O)NCC(C)(O)c1ccc([N+](=O)[O-])cc1.N#Cc1ccc(C(=O)Cl)cc1>>CC(C)S(=O)(=O)NCC(C)(O)c1ccc(NC(=O)c2ccc(C#N)cc2)cc1,,C1CCOC1,,CCN(CC)CC,O,test
US05668157,CN(C)c1ncccc1NC(=NC#N)Oc1ccccc1.NC1(c2ccccc2)CCC1>>CN(C)c1ncccc1NC(=NC#N)NC1(c2ccccc2)CCC1,,C1COCCO1,,CN1CCOCC1,,test
US20020010186A1,C[C@@H]1CNCCN1.O=[N+]([O-])c1ccccc1Br>>C[C@@H]1CN(c2ccccc2[N+](=O)[O-])CCN1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20120028973A1,Brc1cnc(I)nc1.Oc1ccc(-c2ccc(OC(F)(F)F)cc2)cc1>>FC(F)(F)Oc1ccc(-c2ncc(Br)cn2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20130196974A1,COC(=O)c1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(NCC3(CN)COC3)c2c1>>NCC1(CNc2cc(N3CCS(=O)(=O)c4ccccc4C3)nc3ccc(C(=O)O)cc23)COC1,,C1CCOC1,O,[Na+].[OH-],,test
US20100234365A1,COc1cccc([C@H]2CCC(=O)N2c2cnc(Oc3ccc(Cl)cc3)cn2)c1>>O=C1CC[C@H](c2cccc(O)c2)N1c1cnc(Oc2ccc(Cl)cc2)cn1,,ClCCl,,BrB(Br)Br,,test
US20070173488A1,CC(C)(C)OC(=O)Nc1cc([N+](=O)[O-])[nH]n1>>CC(C)(C)OC(=O)Nc1cc(N)n[nH]1,[Pd],CO,,,,test
US20060106029A1,N#Cc1cc(CN2CCN(C(=O)c3cccc(Cl)c3F)CC2)nc(Nc2nccs2)c1.[N-]=[N+]=[N-]>>O=C(c1cccc(Cl)c1F)N1CCN(Cc2cc(-c3nn[nH]n3)cc(Nc3nccs3)n2)CC1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US05541180,Cl.Cl.Cl.Cl.O.c1cnc(NCCCNC[C@H]2CCc3ccccc3O2)nc1.c1cnc(NCCCNC[C@H]2CCc3ccccc3O2)nc1>>Cl.Cl.Cl.Cl.O.c1ccc2c(c1)CC[C@H](CNCCCNC1=NCCCN1)O2.c1ccc2c(c1)CC[C@H](CNCCCNC1=NCCCN1)O2,[Pd],CC(C)O,CO,Cl,[H][H],test
US20030073850A1,CN(C)S(=O)(=O)n1cnc(I)c1.COc1ccc2c(c1[N+](=O)[O-])CCCC2=O>>COc1ccc2c(c1[N+](=O)[O-])CCC=C2c1cn(S(=O)(=O)N(C)C)cn1,,ClCCl,,CC[Mg]Br,,test
US20100298373A1,CCCCOC(=O)CC1c2ccc(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)c(C)c2CCN1C(=O)OC(C)(C)C>>Cc1c(-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)ccc2c1CCN(C(=O)OC(C)(C)C)C2CC(=O)O,,CCO,,[Na+].[OH-],,test
US20130196974A1,COC(=O)C1(NC(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)NC1(CO)CC1,,C1CCOC1,,[BH4-].[Li+],,test
US20140274701A1,Brc1ccc2c(c1)SCO2.CC1(C)OBOC1(C)C>>CC1(C)OB(c2ccc3c(c2)SCO3)OC1(C)C,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US05189042,CCC1C=C(C)C(F)C(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(OCCOCc4ccccc4)C(OC)C3)C(C)C(O[Si](C)(C)C(C)(C)C)CC1=O)C(C)CC2OC>>CCC1C=C(C)C(F)C(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(OCCOCc4ccccc4)C(OC)C3)C(C)C(O)CC1=O)C(C)CC2OC,,CC#N,CCOC(C)=O,,,test
US20100130471A1,COC(=O)NCCCC(O)(c1cncc(Cl)c1-c1cccc(C(C)C)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1>>COC(=O)NCCCC(O)(c1cncc(Cl)c1-c1cccc(C(C)C)c1)[C@@H]1CCCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04600788,CC(=O)OC(C)=O.COC(=O)c1ccc(-c2cc(=O)c3ccc(N)cc3o2)cc1>>COC(=O)c1ccc(-c2cc(=O)c3ccc(NC(C)=O)cc3o2)cc1,,c1ccncc1,,,,test
US20140088094A1,CCOCC1CN(S(=O)(=O)c2ccc(F)cc2)c2cc([N+](=O)[O-])ccc2O1>>CCOCC1CN(S(=O)(=O)c2ccc(F)cc2)c2cc(N)ccc2O1,,CCO,,O=C([O-])O.[Na+],,test
US05698575,COc1ccc2c(=O)c(I)coc2c1.c1ccc2[nH]cnc2c1>>COc1ccc2c(=O)cc(-c3nc4ccccc4[nH]3)oc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04652303,C/C=C/C(=O)Cl.CCC(=O)C1=C(O)CC(c2c(C)cc(C)cc2C)CC1=O>>C/C=C/C(=O)c1c(C)cc(C)c(C2CC(=O)C(C(=O)CC)=C(O)C2)c1C,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20040082611A1,CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)CC1CC(=O)NS(C)(=O)=O.CI.O=C(O)C(F)(F)F>>CN(C(=O)CC1CN(S(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)CCN1)S(C)(=O)=O.O=C(O)C(F)(F)F,,CN(C)C=O,ClCCl,O=C([O-])O.[Na+],,test
US20080207654A1,CCCCc1nn(C(C)CC)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nn(C(C)CC)c(=O)n1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20020049344A1,CC(C)(N)CO.O=C(Cl)C1(Br)CC1>>CC(C)(CO)NC(=O)C1(Br)CC1,,ClCCl,O,[Na+].[OH-],,test
US20110207947A1,CCCCCCCC(O[Si](C)(C)C(C)(C)C)C(O)C(O)/C(=C/C(=O)OC)C(=O)OC.COC(C)(C)OC>>CCCCCCCC(O[Si](C)(C)C(C)(C)C)C1OC(C)(C)OC1/C(=C/C(=O)OC)C(=O)OC,Cc1ccc(S(=O)(=O)O)cc1,CC(C)=O,,CCOCC,,test
US04075207,CC(=O)OC(C)=O.Nc1nc(Cl)c(Cl)nc1S>>Cc1nc2nc(Cl)c(Cl)nc2s1,,Cc1ccccc1C,,,,test
US05633279,COC(=O)C(C)C/C(C)=C/Cc1c(O)c2c(c(C)c1OC)COC2=O>>COc1c(C)c2c(c(O)c1C/C=C(\C)CC(C)C(=O)O)C(=O)OC2,,CO,O,Cl,[Li+].[OH-],test
US20080096921A1,COC(=O)c1cc2ccc(-c3ccc(O)cc3)cc2cn1.OCc1c(-c2c(Cl)cccc2Cl)noc1C1CC1>>COC(=O)c1cc2ccc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C4CC4)cc3)cc2cn1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140051846A1,CN(C)c1cccc2c(S(=O)(=O)Cl)cccc12.COC(CN)OC>>COC(CNS(=O)(=O)c1cccc2c(N(C)C)cccc12)OC,,ClCCl,,CCN(CC)CC,,test
US20110207731A1,COCCN(C)c1n[nH]c2ccc(C3OCCCO3)cc12>>COCCN(C)c1n[nH]c2ccc(C=O)cc12,,CCO,,Cl,,test
US20040110945A1,CCOC(=O)Cc1ccc(Nc2nc3ccccc3o2)c(Cl)c1>>O=C(O)Cc1ccc(Nc2nc3ccccc3o2)c(Cl)c1,,C1CCOC1,,[Na+].[OH-],,test
US20160270399A1,Cc1cccc(-n2nnn(C)c2=O)c1CBr.Cn1[nH]c(=O)cc1-c1ccc(Cl)cc1>>Cc1cccc(-n2nnn(C)c2=O)c1COc1cc(-c2ccc(Cl)cc2)n(C)n1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US06300352B1,C[C@H](Oc1ccc(B(O)O)cc1)[C@H](O)CCc1cccnc1.NC(=O)Nc1ccc(Br)cc1>>C[C@H](Oc1ccc(-c2ccc(NC(N)=O)cc2)cc1)[C@H](O)CCc1cccnc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20130345123A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H]1CCC[C@@H]2SCC[C@H](N)C(=O)N21>>COC(=O)[C@@H]1CCC[C@@H]2SCC[C@H](NC(=O)OC(C)(C)C)C(=O)N21,,CCOC(C)=O,ClCCl,,,test
US05446137,COc1ccc(C(OC[C@@]2(C=CCCCCCO)O[C@@H](n3cc(C)c(=O)[nH]c3=O)C[C@@H]2O[SiH2]C(C)(C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1.CS(=O)(=O)Cl>>COc1ccc(C(OC[C@@]2(C=CCCCCCOS(C)(=O)=O)O[C@@H](n3cc(C)c(=O)[nH]c3=O)C[C@@H]2O[SiH2]C(C)(C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1,,c1ccncc1,,,,test
US04059431,COP(=O)(CCO)OC.O=S(=O)(Cl)CCCl>>C=CS(=O)(=O)OCCP(=O)(OC)OC,,c1ccncc1,,,,test
US20080021026A1,CCOC(CN)OCC.Cc1csc(C=O)c1>>CCOC(CN=Cc1cc(C)cs1)OCC,,O,,Cc1ccccc1,,test
US20160200725A1,CC(C)(C)OC(=O)N1C[C@@H]2CNC[C@@H]2C1.OCCBr>>CC(C)(C)OC(=O)N1C[C@@H]2CN(CCO)C[C@@H]2C1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20070232628A1,CCCCC(C(C)=O)C(=O)Nc1ccc(C(C)C)cc1.NC(=O)c1ccccc1O>>CCCCc1c(C)nc(-c2ccccc2O)n(-c2ccc(C(C)C)cc2)c1=O,,Cc1ccccc1C,,,,test
US20140309192A1,O=[N+]([O-])c1cc(F)c(F)cc1N1CCN(CCC(F)(F)F)CC1>>Nc1cc(F)c(F)cc1N1CCN(CCC(F)(F)F)CC1,,CCO,,Cl[Sn]Cl,,test
US20030065146A1,COCCOCCOCCOCC(=O)OCc1ccccc1>>COCCOCCOCCOCC(=O)O,[Pd],CO,,,,test
US06884821B1,CCOC(=O)/C(=C/c1ccc(OC)c(C(=O)O)c1)OC(C)C.NCc1ccc(C(F)(F)F)cc1>>CCOC(=O)/C(=C/c1ccc(OC)c(C(=O)NCc2ccc(C(F)(F)F)cc2)c1)OC(C)C,,CN(C)C=O,,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20140005213A1,COC[C@@H](C)Oc1cc(F)cc2ccc(-c3nnc4ccc([C@@H](N5CC[C@H](NC(=O)OC(C)(C)C)C5)C(F)(F)F)cn34)nc12.Cl.ClCCl>>COC[C@@H](C)Oc1cc(F)cc2ccc(-c3nnc4ccc([C@@H](N5CC[C@H](N)C5)C(F)(F)F)cn34)nc12.Cl.Cl,,CC#N,ClCCl,,,test
US20140357613A1,C[C@H](Oc1cc(C#C[Si](C)(C)C)cnc1N)c1c(Cl)ccc(F)c1Cl>>C#Cc1cnc(N)c(O[C@@H](C)c2c(Cl)ccc(F)c2Cl)c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US05892121,O=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=S(=O)(O)O>>O=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=S(=O)(O)O,,Clc1ccccc1,,,,test
US20070197512A1,C=CC(=O)OC.Cc1cc(Cl)cc2c1O[C@H](C(C)C)C(=O)N2>>COC(=O)CCN1C(=O)[C@@H](C(C)C)Oc2c(C)cc(Cl)cc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04251539,CCOP(OCC)OCC.Cc1cc(CCl)on1>>CCOP(=O)(Cc1cc(C)no1)OCC,,ClC(Cl)Cl,,,,test
US04824843,Cc1c(N)cccc1C1=NC(C)(C)CO1.Cc1ccc(C)c(OCCCC(C)(C)C(=O)Cl)c1>>Cc1ccc(C)c(OCCCC(C)(C)C(=O)Nc2cccc(C3=NC(C)(C)CO3)c2C)c1,,ClCCl,,CCN(CC)CC,,test
US04440941,CC(=O)Sc1c(Cl)cccc1C(=O)N(CC(=O)OC(C)(C)C)C1CCCC1>>CC(=O)Sc1c(Cl)cccc1C(=O)N(CC(=O)O)C1CCCC1,,CC#N,,C[Si](C)(C)Cl,[I-].[Na+],test
US20030220341A1,C[Si](C)(C)CCOCCl.OCc1nc2ccccc2[nH]1>>C[Si](C)(C)CCOCn1c(CO)nc2ccccc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05071841,COC(=O)C1Cc2ccc(C3CCCCC3)cc2C(=O)CS1>>O=C1CSC(C(=O)O)Cc2ccc(C3CCCCC3)cc21,,CO,,O,[K+].[OH-],test
US20050137204A1,C=O.CNC.c1cc2cc(-c3ccc(O[C@H]4CN5CCC4CC5)nn3)ccc2[nH]1>>CN(C)Cc1c[nH]c2ccc(-c3ccc(O[C@H]4CN5CCC4CC5)nn3)cc12,,C1COCCO1,CC(=O)O,,,test
US20020094989A1,CCCCCCCCCCCCc1ccc(S(=O)(=O)N=[N+]=[N-])cc1.O=C(CC(=O)OCc1ccccc1)OCc1ccccc1>>[N-]=[N+]=C(C(=O)OCc1ccccc1)C(=O)OCc1ccccc1,,CC#N,,CCN(CC)CC,CCOCC,test
US20120108627A1,CC(C)(C#N)c1ccc(N)cc1.O=[N+]([O-])c1cnc2ccc(Cl)cc2c1Cl>>CC(C)(C#N)c1ccc(Nc2c([N+](=O)[O-])cnc3ccc(Cl)cc23)cc1,,CC(=O)O,,O,,test
US04256831,CC(C)(C)NS(=O)(=O)c1ccc2c(N)cccc2c1O.O=S(=O)(Cl)N1CCOCC1>>CC(C)(C)NS(=O)(=O)c1ccc2c(NS(=O)(=O)N3CCOCC3)cccc2c1O,,O,,Cl,c1ccncc1,test
US20100105658A1,COC(=O)c1ccnc(/C=C/c2ccccc2)c1>>COC(=O)C1CCNC(CCC2CCCCC2)C1,O=[Pt],CO,Cl,,,test
US20150315198A1,CNc1cc(C)c(CN)c(C)n1.Clc1ncnc2nn(Cc3ccc(Cn4cccn4)cc3)cc12>>CNc1cc(C)c(CNc2ncnc3nn(Cc4ccc(Cn5cccn5)cc4)cc23)c(C)n1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,,test
US20130065913A1,CC(C)(C)[Si](C)(C)Cl.OCCCSCCCO>>CC(C)(C)[Si](C)(C)OCCCSCCCO,,C1CCOC1,,[H-].[Na+],,test
US20050038053A1,CCOC(=O)c1c(N)sc2c1CCCC2.COc1cc(C(=O)NCc2ccccc2)cc(OC)c1OC>>COc1cc(-c2nc3sc4c(c3c(=O)n2Cc2ccccc2)CCCC4)cc(OC)c1OC,,ClCCCl,,O=P(Cl)(Cl)Cl,,test
US20110034439A1,COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2cc1C(=O)O.CS(=O)(=O)CCN>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2cc1C(=O)NCCS(C)(=O)=O,,CCO,,CCN(CC)CC,Cl,test
US20030064912A1,CC(C)(C)OC(=O)CCC(CP(=O)(CNC(=O)c1ccccc1)OC(C)(C)C)C(=O)OC(C)(C)C>>O=C(O)CCC(CP(=O)(O)CNC(=O)c1ccccc1)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030144338A1,CCOC(=O)[C@@H](O)Cc1ccccc1.Cc1ccc(-c2ccc(O)cc2)n1CCc1ccc(Br)cc1>>CCOC(=O)[C@@H](Cc1ccccc1)Oc1ccc(-c2ccc(C)n2CCc2ccc(Br)cc2)cc1,,Cc1ccccc1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070021401A1,CI.Cn1cnc(C[C@H](N)C(=O)O)c1>>CN1C=C(C[C@H](N)C(=O)O)N(C)C1,,CC#N,,,,test
US20030092712A1,O=C1CCc2c(cc(Br)nc2-c2ccc(F)cc2F)N1c1c(Cl)cccc1Cl>>O=c1ccc2c(-c3ccc(F)cc3F)nc(Br)cc2n1-c1c(Cl)cccc1Cl,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20040152715A1,O=C(N[C@@H]1CC[C@@H](c2ccc(OC(=O)OCc3ccccc3)cn2)CC1)OCc1ccccc1>>O=C(N[C@@H]1CC[C@@H](c2ccc(O)cn2)CC1)OCc1ccccc1,,CO,,[Na+].[OH-],,test
US20120264790A1,COC(=O)c1ccc(F)c([N+](=O)[O-])c1.OC1CC(F)(F)C1>>COC(=O)c1ccc(OC2CC(F)(F)C2)c([N+](=O)[O-])c1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20110028467A1,CN(C)c1cccc(-c2cnc3c(c2)NCCO3)c1.COc1c(Br)cc(C(=O)Cl)cc1Br>>COc1c(Br)cc(C(=O)N2CCOc3ncc(-c4cccc(N(C)C)c4)cc32)cc1Br,,ClCCl,,CCN(CC)CC,,test
US20050277674A1,CN(C)C1(c2ccccc2)CCC(CNC(=O)Oc2ccccc2)CC1.COc1ccc2[nH]cc(C3CCNCC3)c2c1>>COc1ccc2[nH]cc(C3CCN(C(=O)NCC4CCC(c5ccccc5)(N(C)C)CC4)CC3)c2c1,,C1COCCO1,,,,test
US20150191465A1,C[C@H](N)c1nc2ccn(C)c2cc1Br.OC1CCCNC1>>C[C@H](N)c1nc2ccn(C)c2cc1N1CCCC(O)C1,,C1COCCO1,,CC(C)(C)[O-].[K+],,test
US05482916,CC(=O)OC(C)=O.Oc1nsnc1-c1c(Cl)cccc1Cl>>CC(=O)Oc1nsnc1-c1c(Cl)cccc1Cl,,CCOCC,,O,c1ccncc1,test
US05721234,CCN(C(C)C)C(C)C.CCOC(C)=O.Nc1c(Br)cc2c(c1[N+](=O)[O-])CC(N)C2>>Nc1c(Br)cc2c(c1[N+](=O)[O-])CC(N1CCCC1)C2,,CN(C)C=O,,CO,Cl,test
US20150119380A1,BrBr.O=c1ccc2ccc(CCCO)cc2o1>>O=c1oc2cc(CCCO)ccc2cc1Br,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US05834454,CCOC(=O)COCCO.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOC(=O)COCCOS(=O)(=O)c1ccc(C)cc1,,O,,CCN(CC)CC,ClCCl,test
US20130316943A1,COC(=O)c1ccc(C(=O)OC)c(B2OC(C)(C)C(C)(C)O2)c1>>CC1(C)OB(c2cc(CO)ccc2CO)OC1(C)C,,ClCCl,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20090162283A1,CC(N)=S.N#Cc1ccc(-c2cn3cc(I)ccc3n2)cc1>>NC(=S)c1ccc(-c2cn3cc(I)ccc3n2)cc1,,CN(C)C=O,,Cl,,test
US20110105544A1,CC(=O)OCBr.O=C(O)C(CCCc1ccccc1)CCc1ccccc1>>CC(=O)OCOC(=O)C(CCCc1ccccc1)CCc1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,O,test
US20030100556A1,CN1CCN(c2cccc3c2C[C@H](NC(=O)c2ccc(N4CCN(Cc5ccccc5)CC4)cc2)CO3)CC1>>CN1CCN(c2cccc3c2CC(NC(=O)c2ccc(N4CCNCC4)cc2)CO3)CC1,[Pd],CO,,O=C[O-].[NH4+],,test
US20070135456A1,C=CCn1c(Cl)nc2c1c(=O)[nH]c(=O)n2CCCCC.CI>>C=CCn1c(Cl)nc2c1c(=O)n(C)c(=O)n2CCCCC,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060270706A1,CCOC(=O)CCCn1nncc1/C=C1\CN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CCC1SC(C)=O.O=C(O)C(F)(F)F>>CCOC(=O)CCCn1nncc1/C=C1\CNCCC1SC(C)=O.O=C(O)C(F)(F)F,,ClCCl,,,,test
US04569801,CCCCCCC(=O)Cl.CCNC(C)CCCc1ccc([N+](=O)[O-])cc1>>CCCCCCC(=O)N(CC)C(C)CCCc1ccc([N+](=O)[O-])cc1,,CC(C)=O,,O,O=C([O-])[O-].[Na+].[Na+],test
US20100249119A1,N#C[S-].O=[N+]([O-])c1cnc(Cl)nc1Cl>>N#CSc1nc(Cl)ncc1[N+](=O)[O-],,CC(=O)O,,O,,test
US20130217878A1,CCOC(=O)c1ccc(F)cc1OCOC.c1cnc2cc[nH]c2c1>>CCOC(=O)c1ccc(-n2ccc3ncccc32)cc1OCOC,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100311730A1,CN(C)CC(=O)Nc1cnc(Nc2cnc(C#N)cn2)cc1OCC1CCN(C(=O)OC(C)(C)C)CC1>>CN(C)CC(=O)Nc1cnc(Nc2cnc(C#N)cn2)cc1OCC1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150329557A1,CCOC(OCC)OCC.Nc1cccc(CCC(=O)O)c1.[N-]=[N+]=[N-]>>O=C(O)CCc1cccc(-n2cnnn2)c1,,CC(=O)O,,O,,test
US20070003539A1,COC(=O)c1cc(OC)ccc1-n1nc(C)cc1C>>COc1ccc(-n2nc(C)cc2C)c(CO)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100144694A1,CC1(C)NN(C2C3CC4CC(C3)CC2C4)C1=O.O=C=Nc1ccc(Cl)cc1>>CC1(C)C(=O)N(C2C3CC4CC(C3)CC2C4)N1C(=O)Nc1ccc(Cl)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20130331409A1,CC1(C)OB(c2ccc(Oc3nc4ccccc4[nH]3)cc2)OC1(C)C.CCn1nc2cccnc2c1Br>>CCn1nc2cccnc2c1-c1ccc(Oc2nc3ccccc3[nH]2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Cs+].[Cs+],test
US03974212,CC1(C2CCCC2)Cc2cc(OC(=O)c3nnn[nH]3)c(Cl)c(Cl)c2C1.NO>>CC1(C2CCCC2)Cc2cc(OC(=NO)c3nnn[nH]3)c(Cl)c(Cl)c2C1,,c1ccncc1,,Cl,Cl,test
US20130123277A1,CC1(c2ccncn2)CO1.Cc1ccc2[nH]c3c(c2c1)CCN(C)C3>>Cc1ccc2c(c1)c1c(n2CC(C)(O)c2ccncn2)CN(C)CC1,,CN(C)C=O,O,[H-].[Na+],,test
US20120202785A1,CS(=O)(=O)Cl.Cc1ccccc1-c1c(CO)sc2ccccc12>>Cc1ccccc1-c1c(COS(C)(=O)=O)sc2ccccc12,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20140315889A1,C=C1CCc2c(c3cc(F)ccc3n2CCCCCC(=O)OCC)C1=O.CC1CNCC(C)O1>>CCOC(=O)CCCCCn1c2c(c3cc(F)ccc31)C(=O)C(CN1CC(C)OC(C)C1)CC2,,Cc1ccccc1,,,,test
US20090093454A1,CC(C)(C)OC(=O)n1c(CN2CC[C@H]3CCc4cccnc4[C@@H]32)nc2ccccc21>>c1cnc2c(c1)CC[C@@H]1CCN(Cc3nc4ccccc4[nH]3)[C@@H]21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100041760A1,CC(C)Sc1cc(C(F)(F)F)cc(S(=O)(=O)N(C)[C@@H]2CCCc3c(OCC(=O)OC(C)(C)C)cccc32)c1.O=C(OO)c1cccc(Cl)c1>>CC(C)S(=O)c1cc(C(F)(F)F)cc(S(=O)(=O)N(C)[C@@H]2CCCc3c(OCC(=O)OC(C)(C)C)cccc32)c1,,ClCCl,,,,test
US20080090861A1,Cc1cccc(-n2nc3c(c2O)CCC3)n1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1cccc(-n2nc3c(c2OS(=O)(=O)C(F)(F)F)CCC3)n1,,ClCCl,,CCN(CC)CC,,test
US20110015175A1,CI.Cc1ncn(-c2c(F)cc(NC(N)=S)cc2F)n1>>CSC(=N)Nc1cc(F)c(-n2cnc(C)n2)c(F)c1.I,,CCO,,,,test
US20050197328A1,BrBr.O=[N+]([O-])c1cnccc1O>>O=[N+]([O-])c1cncc(Br)c1O,,O,,,,test
US20110124665A1,COC(=O)CCCBr.COc1ccc(-c2c(-c3ccccc3)oc3ncnc(OCC4CCCN4)c23)cc1>>COC(=O)CCCN1CCCC1COc1ncnc2oc(-c3ccccc3)c(-c3ccc(OC)cc3)c12,,C1CCOC1,O,CCN(C(C)C)C(C)C,[I-].[K+],test
US20100075948A1,CC(C)(C)C/C=N/CC(=O)OC(C)(C)C.N#C/C(=C\c1cccc(Cl)c1F)c1ccc(Cl)cc1Cl>>CC(C)(C)CC1NC(C(=O)OC(C)(C)C)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1Cl,,ClCCl,,CCN(CC)CC,,test
US20050059657A1,CC(C)(C)c1ccc(N)cc1.N#CCC(=O)O>>CC(C)(C)c1ccc(NC(=O)CC#N)cc1,,ClCCl,,,,test
US20120225844A1,CCOC(=O)c1cc(COc2ccccc2)nn1CCNC(=O)OC(C)(C)C>>O=C1NCCn2nc(COc3ccccc3)cc21,,C1COCCO1,Cl,O=C([O-])[O-].[Na+].[Na+],,test
US20120094972A1,Cc1c(-c2ccccn2)nc2cc(F)ccc2c1N1CC(C)(C)c2ncc(B(O)O)cc21.Nc1nccc(Cl)n1>>Cc1c(-c2ccccn2)nc2cc(F)ccc2c1N1CC(C)(C)c2ncc(-c3ccnc(N)n3)cc21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090306016A1,O=C(CCCCCCOc1ccc(OCc2ccccc2)cc1)c1nnc(COCc2ccccc2)o1>>O=C(CCCCCCOc1ccc(O)cc1)c1nnc(COCc2ccccc2)o1,[Pd],CCOC(C)=O,,,,test
US20160058763A1,CC(C)(C)OC(=O)N1CC(Nc2ccc(C#N)c3ncncc23)C(c2ccc(OC(F)(F)F)cc2)C1.OO>>CC(C)(C)OC(=O)N1CC(Nc2ccc(C(N)=O)c3ncncc23)C(c2ccc(OC(F)(F)F)cc2)C1,,CS(C)=O,,[Na+].[OH-],,test
US20090325985A1,CC(C)(C)OC(=O)N1CCc2c(cc(C#N)c(=O)n2-c2ccccc2)C1>>N#Cc1cc2c(n(-c3ccccc3)c1=O)CCNC2,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100272680A1,CC(C)(CO)NC1CCN(C(=O)OCc2ccccc2)CC1.O=C(n1ccnc1)n1ccnc1>>CC1(C)COC(=O)N1C1CCN(C(=O)OCc2ccccc2)CC1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US05104888,CC(=O)OC(C)=O.Cc1c(C)c2c(c(C)c1O)CCC(C)(COc1ccc([N+](=O)[O-])cn1)O2>>CC(=O)Oc1c(C)c(C)c2c(c1C)CCC(C)(COc1ccc([N+](=O)[O-])cn1)O2,,c1ccccc1,,c1ccncc1,,test
US06127414,COc1ccc([C@H](CO)NC(=O)[C@H](CCCNC(=O)OCc2ccccc2)NC(=O)C(c2ccccc2)c2ccccc2)cc1.Cl>>COc1ccc([C@H](CO)NC(=O)[C@H](CCCN)NC(=O)C(c2ccccc2)c2ccccc2)cc1.Cl,[Pd],CO,,,,test
US20100137394A1,COc1ccc(CC(=O)N2CCC(c3ccc(N)cc3)=N2)cc1OC.Cc1nnsc1C(=O)O>>COc1ccc(CC(=O)N2CCC(c3ccc(NC(=O)c4snnc4C)cc3)=N2)cc1OC,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090105327A1,Nc1ccc(Cl)cc1Cl.O=C1c2ccccc2COc2cc(F)ccc21>>O=C1c2ccccc2COc2cc(Nc3ccc(Cl)cc3Cl)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US05843983,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1CCOc1ccc(F)cc1CCc1ccc(F)c(F)c1.Cl>>Cl.O[C@H]1CN[C@H](CCOc2ccc(F)cc2CCc2ccc(F)c(F)c2)C1,,C1COCCO1,,,,test
US08012980B2,CCN(C(=O)OC(C)(C)C)[C@@H](CO)CNC.O=c1c2ccc(Br)cc2c(CBr)cn1S(=O)(=O)c1ccccc1>>CC(C)(C)OC(=O)N1CCN(Cc2cn(S(=O)(=O)c3ccccc3)c(=O)c3ccc(Br)cc23)C[C@@H]1CO,,C1CCOC1,O,CCN(C(C)C)C(C)C,,test
US20030171411A1,Nc1ccccn1.O=C(O)C(SC1CCCC1)c1ccc(C(F)(F)F)cc1>>O=C(Nc1ccccn1)C(SC1CCCC1)c1ccc(C(F)(F)F)cc1,,C1CCOC1,,,,test
US20080280974A1,Cc1cc(C)[nH]n1.Cc1cc2c(cc1OCCOS(C)(=O)=O)C(C)(C)CC1(CC(C)(C)c3cc(OS(C)(=O)=O)c(C)cc3O1)O2>>Cc1cc(C)n(CCOc2cc3c(cc2C)OC2(CC3(C)C)CC(C)(C)c3cc(OS(C)(=O)=O)c(C)cc3O2)n1,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20050090491A1,Cc1ccc(C(=O)NNC(=O)OC(C)(C)C)cc1-c1ccc(C(=O)NCC2CC2)cc1>>Cc1ccc(C(=O)NN)cc1-c1ccc(C(=O)NCC2CC2)cc1,,O=C(O)C(F)(F)F,,,,test
US20070208010A1,FC(F)(F)c1nc2cncc(Br)n2n1.NN>>NNc1nccn2nc(C(F)(F)F)nc12,,CCO,,Br,O,test
US20060094767A1,C[C@@]1(Cn2cc([N+](=O)[O-])nc2Cl)CO1.FC(F)(F)Oc1ccc(C2=CCNCC2)cc1>>C[C@]1(CN2CC=C(c3ccc(OC(F)(F)F)cc3)CC2)Cn2cc([N+](=O)[O-])nc2O1,,CN(C)C=O,,O,[H-].[Na+],test
US20030114524A1,CCOC(=O)C(CCCCCCCC[C@H]1C[C@]2(C)[C@@H](O)CC[C@H]2[C@@H]2CCc3cc(O)ccc3[C@H]21)CCCCCC(F)(F)C(F)(F)F>>C[C@]12C[C@H](CCCCCCCCC(CCCCCC(F)(F)C(F)(F)F)C(=O)O)[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2O,,C1CCOC1,CCO,[Na+].[OH-],[Cl-].[NH4+],test
US06593300B1,COC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C.O=C([O-])Cc1ccc([N+](=O)[O-])cc1>>COC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(C)C,,CN(C)C=O,,,,test
US20100216746A1,C[Si](C)(C)CCOCn1cnc(Cl)c1C(=O)NCc1ccc(Cl)c(Oc2cc(C#N)cc(CC3CC3)c2)c1F>>N#Cc1cc(CC2CC2)cc(Oc2c(Cl)ccc(CNC(=O)c3[nH]cnc3Cl)c2F)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080242661A1,Cn1ncc(N)c1C(N)=O.O=C(n1ccnc1)n1ccnc1>>CN1N=CC2N=C(O)N=C(O)C21,,CC#N,,,,test
US20120202785A1,Clc1ncnc2c1ncn2C1CCCCO1.N[C@@H](COCc1ccccc1)c1nc2ccc(F)cc2n1-c1ccccc1>>Fc1ccc2nc([C@H](COCc3ccccc3)Nc3ncnc4nc[nH]c34)n(-c3ccccc3)c2c1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US04598149,CCOC(=O)C(Cl)C(C)=O.COc1ccc(C(=N)N)cc1.ClC(Cl)Cl>>Cc1ncnc(O)c1Cl,,ClC(Cl)Cl,,,,test
US20090156603A1,COC(=O)CCSc1cccnc1Nc1nc2cccnc2s1.N#Cc1ccc(F)cc1>>N#Cc1ccc(Sc2cccnc2Nc2nc3cccnc3s2)cc1,,CS(C)=O,,CCOC(C)=O,CC(C)(C)[O-].[K+],test
US04777254,CC12CCC(C(=O)OC1=O)C2(C)C.NCCc1ccccn1>>CC12CCC(C(=O)N(CCc3ccccn3)C1=O)C2(C)C,,c1ccncc1,,,,test
US20120035231A1,COC(=O)C(C)(C)Nc1ccc(C(N)=O)c(F)c1.N#Cc1ccc(N=C=S)cc1C(F)(F)F>>CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=S)N1c1ccc(C(N)=O)c(F)c1,,CS(C)=O,O,,,test
US20150141406A1,CC1(C)OB(c2ccc(CC#N)cc2)OC1(C)C.COc1nccc2c1c(OS(=O)(=O)C(F)(F)F)nn2C1CCCC1>>COc1nccc2c1c(-c1ccc(CC#N)cc1)nn2C1CCCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US20090143396A1,COC(=O)Cc1cc(Br)cc([N+](=O)[O-])c1>>COC(=O)Cc1cc(N)cc(Br)c1,[Fe],O,,CC(=O)O,,test
US06492378B1,CC1(C)Cc2ccc([N+](=O)[O-])cc2C=N1>>CC1(C)Cc2ccc([N+](=O)[O-])cc2CN1,,CO,,[BH4-].[Na+],,test
US20130053365A1,Cn1ncnc1C1C2=NCC(=O)C=C3C2=C(C(C(=O)OC(C)(C)C)=NN3F)C([N+](=O)[O-])C1c1ccc(F)cc1>>Cn1ncnc1C1C2=C3C(=CC1c1ccc(F)cc1)C=NN(F)C3=CC(=O)CN2,,CC(=O)O,,Cl,,test
US20100016295A1,COC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(-c2ccc(N)cc2)cc1.O=C=Nc1ccccc1Cl>>COC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(-c2ccc(NC(=O)Nc3ccccc3Cl)cc2)cc1,,ClCCl,,,,test
US20080200501A1,CC1(C)C2CC[C@]1(C)C(=O)C2.CCOC(=O)C(=O)OCC>>CCOC(=O)/C(O)=C1\C(=O)C2(C)CCC1C2(C)C,,Cc1ccccc1,,[H-].[Na+],,test
US20090176775A1,CC(Br)Br.COC(=O)c1ccc(O)c(N)c1>>COC(=O)c1ccc2c(c1)NCCO2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US03932428,CN=C=O.On1c(C(F)(F)F)nc2nc(Br)c(Cl)c(Br)c21>>CNC(=O)On1c(C(F)(F)F)nc2nc(Br)c(Cl)c(Br)c21,,CCOCC,CCOCC,CCN(CC)CC,,test
US05541344,COc1cc(N)c(Cl)cc1C(=O)O.O=C(n1ccnc1)n1ccnc1>>NC(=O)c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160222056A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](C(=O)O)CC1.COC(=O)[C@@H](N)Cc1ccc(Br)cc1>>COC(=O)[C@H](Cc1ccc(Br)cc1)NC(=O)[C@@H]1CC[C@@H](CNC(=O)OC(C)(C)C)CC1,,CCOC(C)=O,O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20070037829A1,CCS(N)(F)(F)(F)CC.O=C1c2ccccc2C(=O)N1[C@@H]1CC[C@@H](OCC(O)c2ccccc2)CC1>>O=C1c2ccccc2C(=O)N1[C@@H]1CC[C@@H](OCC(F)c2ccccc2)CC1,,ClCCl,,,,test
US20070129347A1,CN(C)C1(c2ccccc2)CCC(=CC(=O)NCCCc2c[nH]c3ccccc23)CC1>>CN(C)C1(c2ccccc2)CCC(CC(=O)NCCCc2c[nH]c3ccccc23)CC1,[Pd],CO,,Cl,,test
US20120178742A1,COC(=O)c1nn2cc(Br)ccc2c1C(=O)OC>>O=C(O)c1cc2ccc(Br)cn2n1,,O=S(=O)(O)O,,Cl,[Na+].[OH-],test
US20110034452A1,CCc1ccc(NN)nn1.N#CBr>>CCc1ccc2nnc(N)n2n1,,CCO,O,Cl,,test
US06350749B1,NN.O=C1CC(=O)CC(c2ccccc2Cl)C1.O=Cc1ccccc1>>O=C1CC(c2ccccc2Cl)Cc2[nH]nc(-c3ccccc3)c21,,CCO,,Cl,,test
US20110281841A1,CCOC(=O)c1cn(-c2nc(Cl)ncc2F)nc1C>>Cc1nn(-c2nc(Cl)ncc2F)cc1CO,,C1CCOC1,Cc1ccccc1,CC(C)C[Al+]CC(C)C.[H-],,test
US07179823B1,COC(=O)c1c[nH]cc1-c1ccccc1.Cc1oc(-c2ccccc2)nc1COc1ccc(CCl)cc1>>COC(=O)c1cn(Cc2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)cc1-c1ccccc1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20060052599A1,O=C(O)CC(=O)O.O=Cc1ccc(NC2Cc3ccccc3C2)nc1>>O=C(O)/C=C/c1ccc(NC2Cc3ccccc3C2)nc1,,c1ccncc1,,C1CCNCC1,,test
US05654326,CCc1c(C(=O)C(N)=O)c2cc(OCCCC(=O)OC(C)(C)C)ccc2n1Cc1ccccc1>>CCc1c(C(=O)C(N)=O)c2cc(OCCCC(=O)O)ccc2n1Cc1ccccc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20080318935A1,COC(=O)[C@@H](NC(=O)c1nc(-c2ccccc2)n2c1CN(C(=O)OC(C)(C)C)CC2)C(C)(C)C>>CC(C)(C)OC(=O)N1CCn2c(-c3ccccc3)nc(C(=O)N[C@H](C(=O)O)C(C)(C)C)c2C1,,C1CCOC1,O,[Li+].[OH-],,test
US20100063038A1,Nc1ccc(Br)cc1F.O=C=Nc1cccc(C(F)(F)F)c1>>O=C(Nc1cccc(C(F)(F)F)c1)Nc1ccc(Br)cc1F,,C1CCOC1,,,,test
US20160272597A1,CC(=O)OC(C)=O.NC[C@H]1CN(c2ccc(F)c(F)c2)C(=O)O1>>CC(=O)NC[C@H]1CN(c2ccc(F)c(F)c2)C(=O)O1,,ClCCl,,,,test
US20060264460A1,COc1cc(N)cc2c(Nc3ccc(C)c(O)c3)c(C#N)cnc12.O=Cc1cccnc1>>COc1cc(NCc2cccnc2)cc2c(Nc3ccc(C)c(O)c3)c(C#N)cnc12,,CCO,,[BH3-]C#N.[Na+],,test
US20120101134A1,CCOC(=O)CCCc1cccc(-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)c1CC>>CCc1c(CCCC(=O)O)cccc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20130281433A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(-c4ccc5c(ccc(=O)n5C)c4)c3)sc2c1-c1ccc(Cl)cc1>>Cc1cc2nc(-c3ccnc(-c4ccc5c(ccc(=O)n5C)c4)c3)sc2c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20020169317A1,CN1CCNCC1.ClCCOc1cccc2c1c1cccc3c1n2C(c1ccccc1)CO3>>CN1CCN(CCOc2cccc3c2c2cccc4c2n3C(c2ccccc2)CO4)CC1,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US05688821,CCCCCCCC/C=C/CCCCCCCC(=O)Nc1nc(CC(=O)OCC)cs1>>CCCCCCCC/C=C/CCCCCCCC(=O)Nc1nc(CC(=O)O)cs1,,C1CCOC1,,[Na+].[OH-],,test
US05506267,CCCCCCCCCCCCCCCC(=O)OC[C@H](CSCCS(=O)(=O)N(Cc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1)C(=O)OC(C)(C)C)OC(=O)CCCCCCCCCCCCCCC>>CCCCCCCCCCCCCCCC(=O)OC[C@H](CSCCS(=O)(=O)NCc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1)OC(=O)CCCCCCCCCCCCCCC,,O=C(O)C(F)(F)F,,,,test
US05856517,COC(=O)c1ccc(CC(OC)OC)c([N+](=O)[O-])c1>>COC(=O)c1ccc(CC(OC)OC)c(N)c1,,CO,,,,test
US20120238574A1,CC(C)(C)OC(=O)N1CCC(n2cnc3cc(N)ccc32)CC1>>Nc1ccc2c(c1)ncn2C1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090069340A1,Cn1c(CBr)c(Br)c(=O)n1C1CCCCC1.c1ccc(CCCC2CCNCC2)cc1>>Cn1c(CN2CCC(CCCc3ccccc3)CC2)c(Br)c(=O)n1C1CCCCC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090318408A1,CN(C)CCCN.COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(CCCc1ccccc1)CC(F)(F)C(=O)N2C>>COc1cc(C(=O)NCCCN(C)C)ccc1Nc1ncc2c(n1)N(CCCc1ccccc1)CC(F)(F)C(=O)N2C,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20060172983A1,O=C(COCc1ccccc1)Nc1ccc(OC(=O)COCc2ccccc2)cc1>>O=C(CO)Nc1ccc(OC(=O)CO)cc1,[Pd],CO,,,,test
US06713473B1,COC(=O)CCCCCN.O=S(=O)(Cl)c1cccc2ccccc12>>COC(=O)CCCCCNS(=O)(=O)c1cccc2ccccc12,,ClCCl,,CCN(CC)CC,Cl,test
US04950666,Nc1ccccc1Cl.O=C(O)CCCCCCCCCC=C(F)F>>O=C(CCCCCCCCCC=C(F)F)Nc1ccccc1Cl,CN(C)c1ccncc1,CCOCC,O,CCN(CC)CC,O=S(Cl)Cl,test
US06200998B1,CCCc1c(O)ccc2c(CCc3ccccc3)csc12.O=C(OO)c1cccc(Cl)c1>>CCCc1c(O)ccc2c1S(=O)C=C2CCc1ccccc1,,ClCCl,,,,test
US20110152290A1,CCOC(=O)C1(NC(=O)c2ccc(OC)c(OCCc3cccc(C)c3)c2)Cc2ccccc2C1=O>>CCOC(=O)C1(NC(=O)c2ccc(OC)c(OCCc3cccc(C)c3)c2)Cc2ccccc2C1O,,C1CCOC1,,CO,[BH4-].[Na+],test
US04474776,CCCSP(=O)(Cl)OC.Oc1cc(Cl)c2cc3ccccc3cc2c1>>CCCSP(=O)(OC)Oc1cc(Cl)c2cc3ccccc3cc2c1,,Cc1ccccc1,,CCN(CC)CC,CCOC(C)=O,test
US06362375B1,Cc1ccc(C(=O)O)cc1.Cc1ccccc1>>Cc1ccc(C(=O)c2ccc(C)cc2)cc1,,O,,O=C([O-])O.[Na+],,test
US20030087902A1,COc1ccc(-c2c(C(=O)OC(C)(C)C)n(S(=O)(=O)c3cccc(C(F)(F)F)c3)c3ccccc23)cc1>>COc1ccc(-c2c(C(=O)O)n(S(=O)(=O)c3cccc(C(F)(F)F)c3)c3ccccc23)cc1,,O=C(O)C(F)(F)F,,O=C([O-])O.[Na+],,test
US20030168632A1,CCCCC[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](CCl)CC2)CC1.CO[Si](OC)(OC)OC>>CCCCC[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](C[Si](OC)(OC)OC)CC2)CC1,,C1CCOC1,,[Mg],,test
US05041673,CC(C)(C)OC(=O)N[C@@H]1Cc2ccccc2C[C@H]1O>>CC(C)(C)OC(=O)NC1Cc2ccccc2CC1=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20160152626A1,CCOC(=O)C(=O)OCC.COc1cc2c(cc1OC(C)C)C(=O)CCO2>>CCOC(=O)/C(O)=C1\COc2cc(OC)c(OC(C)C)cc2C1=O,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US05789394,CC(C)O.CO[C@@H]1OC[C@@H](CBr)O1>>CC(C)O[C@@H]1OC[C@@H](CBr)O1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20140057899A1,CC(C)(C)[Si](C)(C)OC1CCc2c(-c3cnc4ccccc4c3)c3c(N)ncnc3n2C1>>Nc1ncnc2c1c(-c1cnc3ccccc3c1)c1n2CC(O)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20160145252A1,O=C(NC1C=CCCC1)OCc1ccccc1.O=C(OO)c1cccc(Cl)c1>>O=C(N[C@H]1CCC[C@H]2O[C@@H]12)OCc1ccccc1,,ClCCl,,O=C([O-])O.[Na+],,test
US20150152069A1,CCC(=O)Cl.CNc1cc(Cl)ccc1[N+](=O)[O-]>>CCC(=O)N(C)c1cc(Cl)ccc1[N+](=O)[O-],,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20050113580A1,CNS(=O)(=O)c1cccc(O)c1.Cc1ccc(S(=O)(=O)OCCCCl)cc1>>CNS(=O)(=O)c1cccc(OCCCCl)c1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030092740A1,CCOC(=O)c1cc(C(Br)Br)nn1-c1ccc(OC)cc1.O>>COc1ccc(-n2nc(C=O)cc2C(=O)O)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US05514717,FC(F)(Br)C(F)(Cl)Br.O=C(O)CC(F)=C(F)F>>O=C(O)CC(F)(Cl)C(F)(F)Br,[Zn],,,,,test
US20020193367A1,CC(C)CNc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1C(F)(F)F>>CC(C)CNc1cc(NC(=O)OC(C)(C)C)c(N)cc1C(F)(F)F,[Pd],,,,,test
US20130085148A1,CC(C)[Mg]Br.O=C(c1ccncc1)c1cnc(-c2ccc(F)cc2)s1>>CC(C)C(O)(c1ccncc1)c1cnc(-c2ccc(F)cc2)s1,,C1CCOC1,,,,test
US20090270436A1,COC(=O)c1cc(-c2ccccc2)[nH]c(=O)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1cc(OS(=O)(=O)C(F)(F)F)nc(-c2ccccc2)c1,,c1ccncc1,,,,test
US05834463,Br.O=C(NCC1CC(=O)N(Cc2ccccc2)c2ccccc2N1C(=O)CN1C(=O)c2ccccc2C1=O)OCc1ccccc1>>Br.NCC1CC(=O)N(Cc2ccccc2)c2ccccc2N1C(=O)CN1C(=O)c2ccccc2C1=O,,ClC(Cl)Cl,,CC(=O)O,,test
US20070099925A1,CC(C)(CN)CO.COCc1nccn2c(-c3ccnc(S(C)(=O)=O)n3)c(-c3ccc(F)cc3)nc12>>Cc1nccn2c(-c3ccnc(NCC(C)(C)CO)n3)c(-c3ccc(F)cc3)nc12,,CC#N,,,,test
US05631259,C1CC2=C(C1)O2.Nc1cc[nH]c(=O)n1>>Nc1ccn(C2C=CC(O)C2)c(=O)n1,[Pd],CS(C)=O,,C1CCOC1,,test
US20030105070A1,BrP(Br)Br.CCCCSc1ccc(CO)s1>>CCCCSc1ccc(CBr)s1,,CCOCC,,,,test
US20040132727A1,COc1cc2ncnc(Oc3ccc(N)c([N+](=O)[O-])c3)c2cc1OC.NCCN1CCCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2ncnc(Oc3ccc(NC(=O)NCCN4CCCC4)c([N+](=O)[O-])c3)c2cc1OC,,ClC(Cl)Cl,O,CCN(CC)CC,,test
US20090275537A1,COC(=O)CCC[C@@H](COC(=O)Nc1cc2ccccc2cn1)N(C)C(=O)NCc1ccc(F)cc1Cl>>CN(C(=O)NCc1ccc(F)cc1Cl)[C@@H](CCCCO)COC(=O)Nc1cc2ccccc2cn1,,C1CCOC1,CO,[BH4-].[Li+],,test
US06355653B1,CSc1nc2cc(-c3ccccn3)cc(N)n2n1.O=S(=O)(c1ccccc1)N1OC1c1ccccc1>>CS(=O)c1nc2cc(-c3ccccn3)cc(N)n2n1,,ClCCl,,CCOC(C)=O,CO,test
US04778514,COC(=O)[C@@H](NC(=O)COc1ccc(Cl)cc1)[C@@H](C)O.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)[C@@H](NC(=O)COc1ccc(Cl)cc1)[C@@H](C)OS(=O)(=O)c1ccc(C)cc1,,c1ccncc1,,,,test
US20140221347A1,CNCCO.Cn1nc(NS(C)(=O)=O)c2c(Cl)ccc(-c3ccc(Cl)nc3[C@H](Cc3cc(F)cc(F)c3)NC(=O)C(F)(F)F)c21>>CN(CCO)c1ccc(-c2ccc(Cl)c3c(NS(C)(=O)=O)nn(C)c23)c([C@H](Cc2cc(F)cc(F)c2)NC(=O)C(F)(F)F)n1,,CC(=O)N(C)C,,,,test
US20100016340A1,CC(C)(C)OC(=O)N(CCCl)CCCl.N#CCc1ccc(OC(F)(F)F)cc1.N#CN1CCCCC1>>CC(C)(C)OC(=O)N1CCC(C#N)(c2ccc(OC(F)(F)F)cc2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US06060608,BrCc1ccccc1.CCOC(=O)c1cc(O)c2ccc(Br)cc2c1>>CCOC(=O)c1cc(OCc2ccccc2)c2ccc(Br)cc2c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120232239A1,BrCCCCCCC1(CCCCCCBr)c2cc(Br)ccc2-c2ccc(Br)cc21.CC(C)OB1OC(C)(C)C(C)(C)O1>>CC1(C)OB(c2ccc3c(c2)C(CCCCCCBr)(CCCCCCBr)c2cc(Br)ccc2-3)OC1(C)C,,CCOCC,,[Li]C(C)(C)C,,test
US20040054173A1,CC(C)[Si](C(C)C)(C(C)C)n1cc(C2(O)CCNCC2)c(-c2ccncc2)c1-c1ccc(F)cc1>>OC1(c2c[nH]c(-c3ccc(F)cc3)c2-c2ccncc2)CCNCC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04238618,CC(=O)N1C(=O)N(C(C)=O)C(Cl)C1Cl>>CC(=O)n1ccn(C(C)=O)c1=O,[Zn],CCOCC,,CN(C)C=O,O,test
US20140057953A1,CN.COc1cccc(CCBr)c1>>CNCCc1cccc(OC)c1,,C1CCOC1,,,,test
US20090149505A1,CC(C)C(C)N.COC(=O)c1c(C)cc(Br)cc1CBr>>Cc1cc(Br)cc2c1C(=O)N(C(C)C(C)C)C2,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130079377A1,COC(=O)C(C)c1ccc([N+](=O)[O-])c(F)c1>>COC(=O)C(C)c1ccc(N)c(F)c1,[Pd],CO,,,,test
US20070060545A1,CCc1ccc(Cc2ccccc2N)cc1.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>CCc1ccc(Cc2ccccc2N[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1,,CO,,[Cl-].[NH4+],,test
US20090099207A1,CC#N.CC(C)(C)c1cccc(C2(N=C=O)CC2)c1.O=S1(=O)C=C[C@H](O)[C@H](Cc2ccc(Br)cc2)C1>>CC(C)(C)c1cccc(C2(N3C(=O)O[C@@H]4[C@H](Cc5ccc(Br)cc5)CS(=O)(=O)C[C@@H]43)CC2)c1.N,,CC#N,,C1CCC2=NCCCN2CC1,,test
US04233207,Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.ClP(Cl)c1ccccc1>>Cc1cc(C(C)(C)C)c(OP(Cl)c2ccccc2)c(C(C)(C)C)c1,,CCN(CC)CC,,,,test
US20100249075A1,CC(=O)C1c2ccc(O)cc2C2CCCCC2C1c1ccc(O)cc1>>CC(O)C1c2ccc(O)cc2C2CCCCC2C1c1ccc(O)cc1,,CCO,,[BH4-].[Na+],,test
US20160137636A1,COc1cc(Br)c(F)cc1-c1nncc2cc(S(=O)(=O)Oc3c(F)c(F)c(F)c(F)c3F)ccc12.Nc1ccon1>>COc1cc(Br)c(F)cc1-c1nncc2cc(S(=O)(=O)Nc3ccon3)ccc12,,CCOC(C)=O,,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20040138065A1,FC(F)(F)C(F)(F)CCI.N#CC(C#N)Cc1ccc(Cl)cc1>>N#CC(C#N)(CCC(F)(F)C(F)(F)F)Cc1ccc(Cl)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04301235,CCCCCCCCCCCCCCCCCCNC(=O)NC1=NN(c2c(Cl)cc(Cl)cc2Cl)C(=O)C1Br.Cc1n[nH]cc1[N+](=O)[O-]>>CCCCCCCCCCCCCCCCCCNC(=O)NC1=NN(c2c(Cl)cc(Cl)cc2Cl)C(=O)C1n1cc([N+](=O)[O-])c(C)n1,,CCOC(C)=O,,,,test
US20100160387A1,COc1cc(CC(=O)O)c(Br)cc1C.O=C(Cl)C(=O)Cl>>COc1cc(CC(=O)Cl)c(Br)cc1C,CN(C)C=O,ClCCl,,,,test
US04254135,CN[C@@H]1CN(C2CCCCC2)C[C@H]1O.ClCCl.O=C(Cl)c1ccccc1>>CN(C(=O)c1ccccc1)[C@@H]1CN(C2CCCCC2)C[C@H]1O.Cl,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20150112067A1,CC(=O)C(CC(NC(=O)OC(C)(C)C)C(=O)OC(C)C)c1cc(F)cc(F)c1F.CC(C)N>>C[C@H]1NC(=O)C(NC(=O)OC(C)(C)C)C[C@H]1c1cc(F)cc(F)c1F,,CS(C)=O,O,Cl,,test
US04497827,CCCCCCC#CCC#CCC#CCC#CCCCC(=O)O.CN(C)C=O.O=S(Cl)Cl>>CCCCCCC#CCC#CCC#CCC#CCCCC(=O)NO,,CCOCC,ClCCl,Cl,,test
US04606757,Clc1cccc(C(Oc2ccccc2)Oc2ccccc2)n1>>c1ccc(OC(Oc2ccccc2)c2ccccn2)cc1,[Pd],CCO,,CCN(CC)CC,[H][H],test
US05145865,CO.Cc1ccc(N2CC(C(=O)O)CC2=O)cc1>>COC(=O)C1CC(=O)N(c2ccc(C)cc2)C1,,ClCCl,,O=S(=O)(O)O,,test
US20080312272A1,CC(C#N)(Cn1cc2ncc(Cl)cc2n1)NC(=O)c1ccc(OC(F)(F)F)cc1.O=C1CCC(=O)N1Cl>>CC(C#N)(Cn1nc2cc(Cl)cnc2c1Cl)NC(=O)c1ccc(OC(F)(F)F)cc1,,CC#N,,,,test
US05563141,CCn1cc(C(=O)O)c(=O)c2ccc(Cl)cc21.c1cc(N2CCNCC2)ccn1>>CCn1cc(C(=O)O)c(=O)c2ccc(N3CCN(c4ccncc4)CC3)cc21,,CO,,,,test
US06093345,CC(=O)OC(C)(C)C.CCCC[C@@H](CC(=O)OC)OCc1ccccc1>>CCCC[C@@H](CC(=O)CC(=O)OC(C)(C)C)OCc1ccccc1,,C1CCOC1,,[Cl-].[NH4+],,test
US20070054916A1,C#CC1CC1.Nc1ccc(Br)c(C(F)(F)F)c1>>Nc1ccc(C#CC2CC2)c(C(F)(F)F)c1,,CC#N,,CC(C)c1cc(C(C)C)c(-c2ccccc2P(C2CCCCC2)C2CCCCC2)c(C(C)C)c1,O=C([O-])[O-].[Cs+].[Cs+],test
US20120277224A1,CCOC(=O)CC(=O)c1ccc2c(cnn2COC)c1.Nc1[nH]ncc1-c1ccccn1>>COCn1ncc2cc(-c3cc(=O)n4ncc(-c5ccccn5)c4[nH]3)ccc21,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090105211A1,Clc1nc(-c2ccccc2)c2ccccc2n1.Nc1ccc(C(=O)O)cc1>>O=C(O)c1ccc(Nc2nc(-c3ccccc3)c3ccccc3n2)cc1,,CC(C)O,,,,test
US20090163524A1,Clc1ncnc2[nH]ccc12.NC1(C(=O)NC(CCCO)c2ccc(Cl)cc2)CCNCC1>>NC1(C(=O)NC(CCCO)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1,,CCO,,CCN(C(C)C)C(C)C,,test
US20160237075A1,CC(C)(C)OC(=O)N1C=C(c2ccc(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)n2)CCC1.NC(=O)c1ccc(N2CCC(N)C2)nc1-c1ccc(Oc2ccccc2)cc1>>C=CC(=O)NC1CCN(c2ccc(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)n2)C1,,ClCCl,,,,test
US20060014948A1,BrC(Br)(Br)Br.Cc1cc(CO)ccc1F>>Cc1cc(CBr)ccc1F,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140031559A1,Cc1ccc(S(=O)(=O)OCCOCCOCCOCCOCCOCCOC2CCCCO2)cc1.O=[N+]([O-])c1ccc(O)cc1>>O=[N+]([O-])c1ccc(OCCOCCOCCOCCOCCOCCOC2CCCCO2)cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20020052322A1,COC(=O)[C@@H](N)Cc1cccc2ccccc12.C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O>>COC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)[C@H](C)NC(=O)Cc1cc(F)cc(F)c1,,CO,ClCCl,Cl,,test
US20130225561A1,CC1Cc2cc(CCN3CCN(C(=O)OC(C)(C)C)CC3)ccc2C(=O)O1.Cl>>CC1Cc2cc(CCN3CCNCC3)ccc2C(=O)O1.Cl,,C1COCCO1,,,,test
US20150291623A1,O=C1N(Cc2ccc(Br)o2)c2ccccc2C12COc1cc3c(cc12)CCO3.OB(O)c1ccncc1>>O=C1N(Cc2ccc(-c3ccncc3)o2)c2ccccc2C12COc1cc3c(cc12)CCO3,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US05688830,CC(=O)NC(C)COc1c(C)cccc1C>>CCNC(C)COc1c(C)cccc1C,,CCO,CCOCC,C1CCOC1,,test
US20110311474A1,CCC1CC2(CC1C(=O)O)OCCO2.Cc1ccc(S(=O)(=O)n2ccc3nc(NN)cnc32)cc1>>CCC1CC2(CC1C(=O)NNc1cnc3c(ccn3S(=O)(=O)c3ccc(C)cc3)n1)OCCO2,,ClCCl,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US05968875,C1CCOC1.CCOC(C)=O.CNC(=O)C(=NOC)c1ccccc1CO.O=C(O)c1ccc(Cl)c(Cl)n1>>CCC(CC)(CC)OC(=O)c1ccc(Cl)c(OCc2ccccc2C(=NOC)C(=O)NC)n1,,C1CCOC1,,[H-].[Na+],,test
US03993684,O=C(O)CC(=O)O.O=Cc1cccs1.c1ccncc1>>C=C(C(=O)O)c1cccs1,,c1ccncc1,,C1CCNCC1,,test
US20090137561A1,C=CC1(c2cc(C(=O)OC)ccc2-c2cc(OC)ncc2F)CCCC1>>C=CC1(c2cc(CO)ccc2-c2cc(OC)ncc2F)CCCC1,,C1CCOC1,CCOCC,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04755509,CCOC(=O)COc1ccc(F)cc1[N+](=O)[O-]>>O=C1COc2ccc(F)cc2N1,[Ni],CO,,,,test
US05831094,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)[C@@H](N)CO>>CC(C)[C@H](CO)NC(=O)OC(C)(C)C,,CO,,,,test
US20150210682A1,CCOC=C(C(C)=O)C(=O)OCC.CCOc1ccc(Br)c2c1C=NC(CC)C2>>CCOC(=O)C1=CN2C(CC)Cc3c(Br)ccc(OCC)c3C2CC1=O,,CCO,,,,test
US20090186830A1,CC(C)(C)OC(=O)C1CCC(NCc2ccccc2)CC1.CC(C)(C)OC(=O)CBr>>CC(C)(C)OC(=O)CN(Cc1ccccc1)C1CCC(C(=O)OC(C)(C)C)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20040209905A1,COc1cc2nccc(Oc3cc(C)c(N)cc3C)c2cc1OC.COc1ccccc1N=C=O>>COc1ccccc1NC(=O)Nc1cc(C)c(Oc2ccnc3cc(OC)c(OC)cc23)cc1C,,ClC(Cl)Cl,,CO,,test
US20100081679A1,Clc1cnc(Nc2ccccc2)nc1Cl.NC1CC1>>Clc1cnc(Nc2ccccc2)nc1NC1CC1,,CC#N,,CCN(CC)CC,O,test
US06521643B1,Cc1cc(N(C)C)cc[n+]1[O-]>>Cc1cc(N(C)C)ccn1,[Ni],CC(C)O,,,,test
US20060094767A1,CC(C)(C)OC(=O)CCC1(C)CO1.O=[N+]([O-])c1c[nH]c(Cl)n1>>CC(O)(CCC(=O)OC(C)(C)C)Cn1cc([N+](=O)[O-])nc1Cl,,CCO,,CC(=O)[O-].[Na+],,test
US20090298820A1,Cn1cc(C=O)c2c(N3CC4CCC(C3)O4)ccnc21.O=C1COc2cc(O)cc(O)c21>>Cn1cc(/C=C2\Oc3cc(O)cc(O)c3C2=O)c2c(N3CC4CCC(C3)O4)ccnc21,,CCO,,Cl,,test
US20160184305A1,COc1cc2[nH]ccc(=O)c2cc1-c1ccc(N(C)C2CC(C)(C)NC(C)(C)C2)nn1.O=P(Cl)(Cl)Cl>>COc1cc2nccc(Cl)c2cc1-c1ccc(N(C)C2CC(C)(C)NC(C)(C)C2)nn1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120077781A1,Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCNc3cccc(C(=O)OC(C)(C)C)c3)c2cc1C>>Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCNc3cccc(C(=O)O)c3)c2cc1C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070213341A1,C=C(CC)C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=C(C)C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)N(C(=O)OC(C)(C)C)c1cc(Cl)ccc12,CN(C)c1ccncc1,ClCCl,,,,test
US05274060,C=Cc1ccc(C=O)cc1.OCCO>>C=Cc1ccc(C2OCCO2)cc1,Cc1ccc(S(=O)(=O)O)cc1,O,,Cc1ccccc1,,test
US05962462,CNCC(O)c1ccccc1.O=S(=O)(Cl)c1ccccc1>>CN(CC(O)c1ccccc1)S(=O)(=O)c1ccccc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20060025415A1,Nc1ccc(S(=O)(=O)Nc2nccs2)cc1.O=C(Cl)c1cc2cc(Cl)cc(Cl)c2[nH]1>>O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)cc1)c1cc2cc(Cl)cc(Cl)c2[nH]1,,ClCCl,,c1ccncc1,,test
US20080261990A1,COCCNCc1ccc(SC(C)(C)C(=O)OC(C)(C)C)cc1.Clc1cc(Cl)ncn1>>COCCN(Cc1ccc(SC(C)(C)C(=O)OC(C)(C)C)cc1)c1cc(Cl)ncn1,,CN(C)C=O,,CCN(CC)CC,O,test
US06114332,O=C(O)c1cccc2c(=O)c3cccc(F)c3[nH]c12>>O=C(O)c1cccc2cc3cccc(F)c3nc12,,CO,O,,,test
US20090181964A1,N#Cc1cccc(C(=O)O)c1.NO>>N=C(NO)c1cccc(C(=O)O)c1,,CO,,,,test
US05273999,C#CCCCCO.COC(=O)CCc1ccccc1O>>C#CCCCCOc1ccccc1CCC(=O)OC,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040210080A1,CCCCC12CCC(=O)C(C)=C1c1cc(F)c(N)c([N+](=O)[O-])c1C2>>CCCCC12CCC(=O)C(C)=C1c1cc(F)c(N)c(N)c1C2,[Pd],CCO,,CC(=O)[O-].[K+],,test
US20160229837A1,Cn1cc2ccc(Nc3ncc(Cl)c(NC4CCNCC4)n3)cc2n1.N#Cc1ccc(Cl)nn1>>Cn1cc2ccc(Nc3ncc(Cl)c(NC4CCN(c5ccc(C#N)nn5)CC4)n3)cc2n1,,CCO,,CCN(CC)CC,,test
US20110190280A1,COCCNC(N)=S.COc1cccc(C(=O)Cc2ccnc(Cl)n2)c1>>COCCNc1nc(-c2cccc(OC)c2)c(-c2ccnc(Cl)n2)s1,,ClCCl,,O=C1CCC(=O)N1Br,,test
US05649537,NCCC1OCCO1.O=C(Cl)C(Cl)COCc1ccccc1>>O=C(NCCC1OCCO1)C(Cl)COCc1ccccc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20080009523A1,CCOC(=O)c1cc(C#N)c(Cl)nc1C.O=S(=O)(Cc1ccccc1)NS(=O)(=O)C1CCNCC1>>CCOC(=O)c1cc(C#N)c(N2CCC(S(=O)(=O)NS(=O)(=O)Cc3ccccc3)CC2)nc1C,,CCO,O,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20070149560A1,CCOC(=O)NN.Cc1cc(Cl)nc2ccc(Cl)cc12>>Cc1cc2n[nH]c(=O)n2c2ccc(Cl)cc12,Cl,CCO,,,,test
US05763437,CC(C)(C)OC(=O)NC1N=C(c2ccccc2F)c2ccccc2NC1=O.CCOC(=O)CBr>>CCOC(=O)CN1C(=O)C(NC(=O)OC(C)(C)C)N=C(c2ccccc2F)c2ccccc21,,CN(C)C=O,,O,[H-].[Na+],test
US06326386B1,CC(C)N(CCCN)C(=O)c1cc(Cl)cc(OCCNc2ccncc2)c1.CS(=O)(=O)Cl.O=C(O)C(F)(F)F>>CC(C)N(CCCNS(C)(=O)=O)C(=O)c1cc(Cl)cc(OCCNc2ccncc2)c1.O=C(O)C(F)(F)F,,CC#N,,CCN(CC)CC,,test
US07612075B2,CN(C)C=O.Clc1ccc(-c2cccs2)s1>>O=Cc1ccc(-c2ccc(Cl)s2)s1,,C1CCOC1,CCOC(C)=O,[Li]CCCC,,test
US20110009395A1,COc1cccc(-c2cccc(C34CC(O[Si](C)(C)C(C)(C)C)CC3CON4Cc3ccccc3)c2)c1>>COc1cccc(-c2cccc(C3(N)CC(O[Si](C)(C)C(C)(C)C)CC3CO)c2)c1,[Pd],CC(=O)O,,,,test
US05712417,CCOC(=O)C(C#N)Cc1ccccc1>>CCOC(=O)C(CN)Cc1ccccc1,[Ni],CCO,,,,test
US20090221603A1,C[SiH](C)C(O)(C1CNCCN1C(c1ccccc1)c1ccccc1)C(C)(C)C.O=C(O)CNC(c1ccccc1)c1ccccc1>>C[SiH](C)C(O)(C1CN(C(=O)CNC(c2ccccc2)c2ccccc2)CCN1C(c1ccccc1)c1ccccc1)C(C)(C)C,CN(C)c1ccncc1,ClCCl,ClCCl,ClCCCl,,test
US20070254867A1,COC(=O)Cc1ccc2c(c1)NC(=O)c1ccc(-c3ccc(-c4ccc(F)nc4)c(OC)c3)cc1N2.O>>COC(=O)Cc1ccc2c(c1)NC(=O)c1ccc(-c3ccc(-c4ccc(=O)[nH]c4)c(OC)c3)cc1N2,,CCOC(C)=O,O,CC(=O)O,,test
US20090170913A1,CN1CCC(N(C)c2nc3cc([N+](=O)[O-])ccc3o2)CC1>>CN1CCC(N(C)c2nc3cc(N)ccc3o2)CC1,[Fe],CC(=O)O,,,,test
US20040067945A1,CCCc1nc(CC)c2c(=O)[nH]c(-c3cc(S(=O)(=O)Cl)ccc3OCC)nn12.CCNCCO>>CCCc1nc(CC)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N(CC)CCO)ccc3OCC)nn12,,ClCCl,,CN(C)c1ccccn1,,test
US20020086874A1,O=C1Cc2cc(Br)ccc2N1.OB(O)c1cccc(Cl)c1>>O=C1Cc2cc(-c3cccc(Cl)c3)ccc2N1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20140171645A1,CS(=O)c1ccccc1.Cc1ccc(C)c(C)c1C.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1cc([S+](C)c2ccccc2)c(C)c(C)c1C.O=S(=O)([O-])C(F)(F)F,,CCOCC,,,,test
US06320051B1,CCN(C(C)C)C(C)C.CCN=C=NCCCN(C)C.CN(C)C=O.ClCCl.O=C(O)c1ccc(Cl)c(Cl)c1.On1nnc2cccnc21>>CO.N.O=C(NCCCCCNc1cc(=O)c2ccccc2[nH]1)c1ccc(Cl)c(Cl)c1,,ClCCl,,Cl,,test
US20110130380A1,CC(C)(C)OC(=O)N1CCOCC(CO)C1>>CC(C)(C)OC(=O)N1CCOCC(C=O)C1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05859034,CSC(=NC#N)SC.Nc1ccc([C@@H](Cc2ccncc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1>>CSC(=NC#N)Nc1ccc([C@@H](Cc2ccncc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1,,CCO,,CCOC(C)=O,,test
US04575507,CCOC(=O)CC1(c2cc(Cl)ccc2OC)NC(=O)NC1=O>>O=C1NC(=O)C2(CC(=O)Oc3ccc(Cl)cc32)N1,,O,,I,,test
US20080058328A1,CC(=O)OCC(=O)Nc1ccccc1[C@@H]1CN(C)Cc2c(Cl)cc(Cl)cc21>>CN1Cc2c(Cl)cc(Cl)cc2[C@H](c2ccccc2NC(=O)CO)C1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20100076014A1,CN(C)C(=O)n1ccc2cc(C(O)c3ccccc3)ccc21.COC(O[Si](C)(C)C)=C(C)C>>COC(=O)C(C)(C)C(c1ccccc1)c1ccc2c(ccn2C(=O)N(C)C)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US04994465,ClCc1ccccc1.NCC(c1ccccc1)c1ccccc1>>c1ccc(CNCC(c2ccccc2)c2ccccc2)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20080318924A1,Br.O=C(CC1(CC(=O)Nc2cc(F)c(Oc3ccnc(NC(=O)N4CC(O)C4)c3)cc2F)CC1)Nc1ccc(F)cc1>>Br.O=C(CC1(CC(=O)Nc2cc(F)c(Oc3ccnc(NC(=O)N4CC(O)C4)c3)cc2F)CC1)Nc1ccc(F)cc1,,CCO,,,,test
US04165377,CN.CN=C(N)Nc1nc(CCCCNC(=NC#N)SC)cs1>>CN=C(N)Nc1nc(CCCCNC(=NC#N)NC)cs1,,CCO,,,,test
US20050020632A1,COc1cc(C(C)=O)ccc1OCCCN1CCC(c2noc3cc(F)ccc23)CC1>>COc1cc([C@H](C)O)ccc1OCCCN1CCC(c2noc3cc(F)ccc23)CC1,,ClCCl,,CO,,test
US20070099990A1,CC1CN1.Cc1cc(C)c(Cc2ccc(C(C)C)cc2)c(OCC(=O)O)c1>>Cc1cc(C)c(Cc2ccc(C(C)C)cc2)c(OCC(=O)N2CC2C)c1,CN(C)C=O,C1CCOC1,O,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20030130278A1,C#CCc1ccccc1.Cn1c(=O)n(Cc2ccc(F)c(F)c2)c(=O)c2cc(I)ccc21>>Cn1c(=O)n(Cc2ccc(F)c(F)c2)c(=O)c2cc(C#CCc3ccccc3)ccc21,[Cu]I,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20130184241A1,ClCc1cccnc1.O=[N+]([O-])c1ccc(O)cc1>>O=[N+]([O-])c1ccc(OCc2cccnc2)cc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20110218171A1,CCCCCCCCCC(=O)O.CNOC>>CCCCCCCCCC(=O)N(C)OC,,ClCCl,,Cl,O,test
US06369034B1,CC(C)(C)OC(=O)CBr.COC(=O)CCN>>COC(=O)CCNCC(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,Cl,test
US20090233902A1,CCOc1ccc2c(ccn2CN(C)C)c1.COC(=O)C(C)[N+](=O)[O-]>>CCOc1ccc2[nH]cc(CC(C)(C(=O)OC)[N+](=O)[O-])c2c1,,Cc1ccccc1,ClC(Cl)Cl,CC(C)=O,,test
US20070213331A1,CCCN(C)C(=O)c1cc(C(=O)OC)cc(C(=O)C(C)C)c1>>CCCN(C)C(=O)c1cccc(C(=O)O)c1C(=O)C(C)C,,CO,,Cl,[Na+].[OH-],test
US20160102072A1,O=S(=O)(OCC(F)(F)F)C(F)(F)F.Oc1ccc(C(F)(F)C2(c3ccc(F)cc3F)CO2)nc1>>Fc1ccc(C2(C(F)(F)c3ccc(OCC(F)(F)F)cn3)CO2)c(F)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04182757,CCCCCN(C(=O)NCCCl)C1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O.O=[N+]([O-])[N+](=O)[O-]>>CCCCCN(C(=O)N(CCCl)N=O)C1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O,,C1CCOC1,ClCCl,O=C([O-])[O-].[Na+].[Na+],,test
US20130303509A1,C#CC1CC1.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>O=C(C#CC1CC1)c1ccc([N+](=O)[O-])cc1,I[Cu]I,C1CCOC1,,CCN(CC)CC,,test
US20120015942A1,COc1ccccc1F.O=C1CCC(=O)O1>>COc1ccc(C(=O)CCC(=O)O)cc1F,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20100105673A1,Cc1cc(Br)c(Cl)cc1CC(=O)O.N#CC1(O)CCCN(C(=O)OCc2ccccc2)C1>>Cc1cc(Br)c(Cl)cc1CC(=O)OC1(C#N)CCCN(C(=O)OCc2ccccc2)C1,CN(C)c1ccncc1,Cc1ccccc1,,ClCCl,,test
US20020019382A1,O=C(C=Cc1ccccc1O)C=Cc1ccccc1O>>Oc1ccccc1C=CC(O)CCc1ccccc1O,,C1CCOC1,CO,[BH4-].[Na+],,test
US20040023938A1,COC(=O)c1cc(Cl)ccc1N.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1cc(Cl)ccc1NS(=O)(=O)c1ccc(C)cc1,,c1ccncc1,,O,,test
US05556981,O=C(O)CC[C@H](NCc1ccccc1)C(=O)O>>O=C(O)[C@@H]1CCC(=O)N1Cc1ccccc1,,O,,,,test
US20150030626A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NNc1ccc(C(=O)O)cn1>>CC(C)(C)OC(=O)NNc1ccc(C(=O)O)cn1,,CN(C)C=O,,Cl,O,test
US20040192912A1,C=C1C(CO)C([Si](C)(C)c2ccccc2)CC1n1cnc2c(=O)[nH]c(N)nc21.CO>>C=C1C(CO)C(O)CC1n1cnc2c(=O)[nH]c(N)nc21,,CO,,CC(=O)O,,test
US20070032478A1,CCn1nc(C)cc1C(=O)Nc1cccc(C(=O)c2ccc3c(c2)C(=CO)C(=O)N3)c1.Nc1ccc(N2CCOCC2)cc1>>CCn1nc(C)cc1C(=O)Nc1cccc(C(=O)c2ccc3c(c2)C(=CNc2ccc(N4CCOCC4)cc2)C(=O)N3)c1,,C1CCOC1,,,,test
US20120227806A1,O=C(O)/C=C/c1ccc(O)cc1.OCCCCCCCl>>O=C(O)C=Cc1ccc(OCCCCCCO)cc1,,O,,CCO,[K+].[OH-],test
US20090105275A1,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCNC2)c1.O=S(=O)(Cl)c1cccc(C(F)(F)F)c1>>CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCN(S(=O)(=O)c3cccc(C(F)(F)F)c3)C2)c1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20030114469A1,CI.COc1cc2cncc(Cc3nc4c([nH]3)c(=O)n(C)c(=O)n4CC(C)C)c2cc1OC>>COc1cc2cncc(Cc3nc4c(c(=O)n(C)c(=O)n4CC(C)C)n3C)c2cc1OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090005376A1,Nc1cnc2ccccc2c1Cl.O=C(Cl)c1ccccc1>>O=C(Nc1cnc2ccccc2c1Cl)c1ccccc1,,CCOC(C)=O,,ClCCl,,test
US20150051208A1,CN1CCN(c2ccc(N)c(NCc3ccccc3)c2)CC1.Cc1cc(C(=O)O)cn(C)c1=O>>Cc1cc(C(=O)Nc2ccc(N3CCN(C)CC3)cc2NCc2ccccc2)cn(C)c1=O,,C1CCOC1,,CCN(CC)CC,,test
US20160168123A1,COC(=O)c1cncc(B2OC(C)(C)C(C)(C)O2)c1.Fc1cc(CCl)ccn1>>COC(=O)c1cncc(Cc2ccnc(F)c2)c1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20070232583A1,CC(C)(C)NS(=O)(=O)c1cccc(-c2cc(-c3cc(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)n3)ccn2)c1>>NS(=O)(=O)c1cccc(-c2cc(-c3cc(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)n3)ccn2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100168062A1,COC(=O)OC(=O)OC.Fc1cc(-c2cccc3ncc(-c4cnn(C5CCNCC5)c4)nc23)cc(F)c1CN1CCOCC1>>COC(=O)N1CCC(n2cc(-c3cnc4cccc(-c5cc(F)c(CN6CCOCC6)c(F)c5)c4n3)cn2)CC1,,C1CCOC1,,,,test
US04752560,ClCCOCCOCCCl.SCCSCCS>>C1COCCSCCSCCSCCO1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06706725B1,CC/C(=C\C=C(Br)Br)c1ccc(COc2ccc(CO[Si](C)(C)C(C)(C)C)c(CO[Si](C)(C)C(C)(C)C)c2)s1>>C#C/C=C(\CC)c1ccc(COc2ccc(CO[Si](C)(C)C(C)(C)C)c(CO[Si](C)(C)C(C)(C)C)c2)s1,,C1CCOC1,,[Li]CCCC,,test
US20100137349A1,CC1(CS(=O)(=O)CCS(=O)(=O)O)COC(=O)N1.CCCCOCl>>CC1(CS(=O)(=O)CCS(=O)(=O)O)COC(=O)N1Cl,,CO,,,,test
US20050107410A1,BrCCBr.Oc1cccc2nc(C(F)(F)F)ccc12>>FC(F)(F)c1ccc2c(OCCBr)cccc2n1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090270391A1,NN.O=Cc1cccc(F)c1F>>Fc1cccc2cn[nH]c12,,O,,CCOC(C)=O,,test
US20080255105A1,CCOC(=O)c1ccc(-c2cc(NC(=O)OC(C)(C)C)ccc2C)cc1>>CCOC(=O)c1ccc(-c2cc(N)ccc2C)cc1,,CCO,,Cl,,test
US20080280875A1,CNC.O=C(O)c1ccc(Br)cn1>>CN(C)C(=O)c1ccc(Br)cn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030153564A1,CC(C)(C)OC(=O)NCCBr.c1cc(CCCCN2CC3CNCC(C2)O3)ccn1>>CC(C)(C)OC(=O)NCCN1CC2CN(CCCCc3ccncc3)CC(C1)O2,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110257011A1,COS(=O)(=O)OC.Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(=NO)N(C)C>>CON=C(c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1C)N(C)C,,CN(C)C=O,O,[Li+].[OH-],,test
US20070043010A1,CC(=O)Oc1ccc2c(OC(C)=O)ncnc2c1.O=S(Cl)Cl>>Oc1ccc2c(Cl)ncnc2c1,CN(C)C=O,,,,,test
US20040023974A1,Cc1cc(OCC(=O)OC(C)(C)C)ccc1[N+](=O)[O-]>>Cc1cc(OCC(=O)OC(C)(C)C)ccc1N,[Pd],CCO,,,,test
US06660745B1,Cc1ccc(S(=O)(=O)O)cc1.Cc1nc(Cl)nc(N)c1N.ClC(Cl)Cl>>Cc1nc2nc(Cl)nc(C)c2[nH]1,,ClC(Cl)Cl,,,,test
US20100016315A1,CCCCc1ccc(N)cc1.N#CC(C(N)=O)C1OC(=O)C(Cl)=C1Cl>>CCCCc1ccc(-n2cc(Cl)cc(C(N)=O)c2=N)cc1,,CCO,,CCN(CC)CC,,test
US20030181519A1,CC(=O)Nc1cccc2ccc(O)cc12.CI>>COc1ccc2cccc(NC(C)=O)c2c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120245144A1,COC(=O)C(C)(C)N1CCC(Sc2ccc3c(c2)-c2nc(-c4ncnn4C(C)C)cn2CCO3)CC1>>CC(C)n1ncnc1-c1cn2c(n1)-c1cc(SC3CCN(C(C)(C)C(=O)O)CC3)ccc1OCC2,,C1CCOC1,O,[Li+].[OH-],,test
US20160024110A1,BrBr.COc1ccc(F)cc1Cl>>COc1cc(Br)c(F)cc1Cl,,O=S(=O)(O)O,,,,test
US04734419,CCOC(=O)Cn1c(=O)n(Cc2ccc(Br)cc2F)c(=O)c2ccc(Cl)cc21>>O=C(O)Cn1c(=O)n(Cc2ccc(Br)cc2F)c(=O)c2ccc(Cl)cc21,,CO,,[Na+].[OH-],,test
US20070043048A1,CC1(C)CC(Nc2nccc(-c3ccc(C#CC4(N)CCCCC4)s3)n2)CC(C)(C)N1>>CC1(C)CC(Nc2nccc(-c3ccc(CCC4(N)CCCCC4)s3)n2)CC(C)(C)N1,[Pd],CO,,[H][H],,test
US20040167122A1,Cl.Nc1ccc(N2CCN(Cc3ccccc3)CC2)cc1CS(=O)(=O)c1ccccc1.O=N[O-]>>Cl.O=S(=O)(c1ccccc1)c1n[nH]c2ccc(N3CCN(Cc4ccccc4)CC3)cc12,,O,,[Na+].[OH-],,test
US20090181989A1,COc1ccc(CCl)cc1.Clc1nc(Cl)c2[nH]cnc2n1>>COc1ccc(Cn2cnc3c(Cl)nc(Cl)nc32)cc1,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090012129A1,CCCCCNC(=O)N(C)c1cccc(-c2ccc(/C=C(\CC)C(=O)OCC)cc2OCCCC)c1>>CCCCCNC(=O)N(C)c1cccc(-c2ccc(/C=C(\CC)C(=O)O)cc2OCCCC)c1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20090239854A1,Brc1ccccn1.CC#N.CCN(CC)CC.Cc1ccc2[nH]c3c(c2c1)CN(C(=O)[O-])CC3>>Cc1ccc2c(c1)c1c(n2CC#Cc2ccccn2)CCN(C)C1,[Cu]I,,,,,test
US20080058335A1,CCOc1ccccc1C(=O)O.O=C(Cl)C(=O)Cl>>CCOc1ccccc1C(=O)Cl,CN(C)C=O,ClCCl,,,,test
US20100113465A1,CON(C)C(=O)C1CC2(CCN(C(=O)OC(C)(C)C)CC2)C1.C[Mg]Br>>CC(=O)C1CC2(CCN(C(=O)OC(C)(C)C)CC2)C1,,C1CCOC1,CCOC(C)=O,CCOCC,,test
US09388176B2,COC(=O)c1ccc(C)c(N2CCc3nc(SC)ncc3C2)c1>>CSc1ncc2c(n1)CCN(c1cc(C(=O)O)ccc1C)C2,,C1COCCO1,,[Na+].[OH-],,test
US08318760B2,COC(=O)c1ccc(CBr)cc1.Oc1cc(-c2ccc(OC(F)(F)F)cc2)cc2ccccc12>>COC(=O)c1ccc(COc2cc(-c3ccc(OC(F)(F)F)cc3)cc3ccccc23)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04971993,CSCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1.O=S(=O)(Cl)c1ccccc1>>CSCC[C@H](NS(=O)(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
US20150094297A1,CC(C)(C)[Si](C)(C)OCc1csc(Br)n1.O=C1CCCCC1>>CC(C)(C)[Si](C)(C)OCc1csc(C2(O)CCCCC2)n1,,C1CCOC1,,[Li]CCCC,,test
US05905074,CC(=O)OC(C)=O.CC(C)(C)O[C@H]1CCC[C@H]2[C@@H](O)CCC[C@@]21C>>CC(=O)O[C@H]1CCC[C@@]2(C)[C@H]1CCC[C@@H]2OC(C)(C)C,CN(C)c1ccncc1,c1ccncc1,,,,test
US20080292588A1,CS1(=O)=NC(C2=C(O)C3C4CCC(C4)C3N(Cc3ccc(F)cc3)C2=O)=Nc2ccc([N+](=O)[O-])cc21>>CS1(=O)=NC(C2=C(O)C3C4CCC(C4)C3N(Cc3ccc(F)cc3)C2=O)=Nc2ccc(N)cc21,[Ni],C1CCOC1,CO,NN,,test
US20070179165A1,CCCC(N)CCC.CCOC(OCC)OCC.N#CCC(=O)c1c(Cl)cccc1Cl>>CCCC(CCC)N/C=C(\C#N)C(=O)c1c(Cl)cccc1Cl,,C1CCOC1,,CC(=O)OC(C)=O,,test
US20110034433A1,CC1=C(C#N)[C@@H](c2ccc(C#N)cc2S(C)(=O)=O)N(C(=O)Oc2ccc([N+](=O)[O-])cc2)C(=O)N1c1cccc(C(F)(F)F)c1.CO[C@@H]1CCCNC1>>CO[C@@H]1CCCN(C(=O)N2C(=O)N(c3cccc(C(F)(F)F)c3)C(C)=C(C#N)[C@H]2c2ccc(C#N)cc2S(C)(=O)=O)C1,,CC#N,,,,test
US04262004,O=[N+]([O-])O.c1ccc2c(c1)SC1=NCCN12>>O=[N+]([O-])O.c1ccc2c(c1)SC1=NCCN12,,CC(C)O,,,,test
US20090137580A1,CS(=O)(=O)O.Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(Cl)c3)c21>>CS(=O)(=O)O.Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(Cl)c3)c21,,CC#N,,,,test
US20150087646A1,CC(C)(C)C(=O)Cl.Cc1ccc(-n2nc(-c3cc(CN)ccc3Cl)[nH]c2=O)cc1Cl>>Cc1ccc(-n2nc(-c3cc(CNC(=O)C(C)(C)C)ccc3Cl)[nH]c2=O)cc1Cl,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20140343092A1,COC(=O)CN(C)C(=O)c1c(C(=O)OC)c2c(n1Cc1ccc(F)cc1)CCOC2>>COC(=O)c1c(O)c2c3c(n(Cc4ccc(F)cc4)c2c(=O)n1C)CCOC3,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20140194469A1,BrCc1ccccc1.OCc1ccc(Cl)cc1O>>OCc1ccc(Cl)cc1OCc1ccccc1,,CCO,,[Na+].[OH-],,test
US20060004005A1,CC(C)(C)OC(=O)CC(=O)OC(C)(C)C.Nc1nc(Cl)nc(Oc2ccc3ccccc3c2)n1>>CC(C)(C)OC(=O)C(C(=O)OC(C)(C)C)C1(N)N=CN=C(Oc2ccc3ccccc3c2)N1,,C1CCOC1,,[H-].[Na+],,test
US20120094917A1,CC(C(=O)NC(C(=O)N1CCC2C1C(C(=O)Nc1ccccc1)CN2C(=O)OCc1ccccc1)C1CCCCC1)N(C)C(=O)OC(C)(C)C>>CC(C(=O)NC(C(=O)N1CCC2NCC(C(=O)Nc3ccccc3)C21)C1CCCCC1)N(C)C(=O)OC(C)(C)C,[Pd],CO,,,,test
US04182758,CCOP(=O)(CC(Br)CBr)OCC>>CCOP(=O)(/C=C\CBr)OCC,,CC(C)(C)O,,CC(C)(C)[O-].[K+],,test
US20130203768A1,CCN(CC)S(F)(F)F.Cc1cc(N2CCN(C(=O)/C=C/C(C)O)CC2)c2ccccc2n1>>Cc1cc(N2CCN(C(=O)/C=C/C(C)F)CC2)c2ccccc2n1,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US05977139,COc1ccc(-c2nnn[nH]2)cc1C(=O)O.O=C(Cl)C(=O)Cl>>COc1ccc(-c2nnn[nH]2)cc1C(=O)Cl,CN(C)C=O,ClCCl,,,,test
US20080167287A1,CC(C)(C)OC(=O)[C@@H](N)C(C)(C)C.Nc1ncc(-c2ccc(C(=O)O)nc2)cn1>>CC(C)(C)OC(=O)[C@@H](NC(=O)c1ccc(-c2cnc(N)nc2)cn1)C(C)(C)C,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20140163001A1,CCOC(=O)c1cnn(C)c1-c1ccc(F)cc1>>Cn1ncc(C(=O)O)c1-c1ccc(F)cc1,,CCO,,Cl,[Na+].[OH-],test
US20130053398A1,FC1(F)Oc2ccc(CN3CCNCC3)cc2O1.O=C(Nc1cccnc1)Oc1ccccc1>>O=C(Nc1cccnc1)N1CCN(Cc2ccc3c(c2)OC(F)(F)O3)CC1,,CS(C)=O,,O,,test
US20090264414A1,C=O.CC1(C)CC2CC(C)(CN2C(=O)c2ccc3[nH]ccc3c2)C1.CS(=O)[O-]>>CC1(C)CC2CC(C)(CN2C(=O)c2ccc3[nH]cc(CS(C)(=O)=O)c3c2)C1,,CN(C)C=O,,CC(=O)O,,test
US20100160324A1,CI.COc1ccc(Cn2cc([N+](=O)[O-])c(-c3n[nH]c(=O)n3Cc3ccc(OC)cc3)n2)cc1>>COc1ccc(Cn2cc([N+](=O)[O-])c(-c3nn(C)c(=O)n3Cc3ccc(OC)cc3)n2)cc1,,CCO,,[Na+].[OH-],,test
US20100305133A1,CCCC[Sn](CCCC)(CCCC)c1ccccn1.CCOC(=O)CNC(=O)c1c(O)cc(Br)c2nccnc12>>O=C(O)CNC(=O)c1c(O)cc(-c2ccccn2)c2nccnc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CO,[Na+].[OH-],,test
US20030018032A1,Cc1ccccc1C=O.Nc1ncccn1.[C-]#[N+]CCCC>>CCCCNc1c(-c2ccccc2C)nc2ncccn12,,[O-][Cl+3]([O-])([O-])O,,,,test
US20090088425A1,Cc1cncc(C(O)(C(C)c2ccc(Cl)cc2Cl)C(F)(F)F)n1>>Cc1cncc([C@](O)([C@H](C)c2ccc(Cl)cc2Cl)C(F)(F)F)n1,,CCCCCCC,,CC(C)O,,test
US20120115850A1,CC(N)c1cccc(Br)c1.O=[N+]([O-])c1ccc(F)cc1F>>CC(Nc1cc(F)ccc1[N+](=O)[O-])c1cccc(Br)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20100069629A1,BrCCc1cccc(Br)c1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(CCc2cccc(Br)c2)CC1,,CCOC(C)=O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20140171403A1,Cc1cc(COC(=O)N2CCC(N)CC2)cc(C(F)(F)F)c1.O=C(Cl)CCCc1c[nH]nn1>>Cc1cc(COC(=O)N2CCC(NC(=O)CCCc3c[nH]nn3)CC2)cc(C(F)(F)F)c1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US05494908,COc1ccc2c(N(C)CCN3CCOCC3)noc2c1>>CN(CCN1CCOCC1)c1noc2cc(O)ccc12,,Br,,O=C([O-])[O-].[Na+].[Na+],,test
US20100311966A1,CCCO[C@@H]1CN(c2ncc(C(=O)OCC)s2)CC[C@@H]1NC(=O)c1nc(Cl)c(CC)[nH]1>>CCCO[C@@H]1CN(c2ncc(C(=O)O)s2)CC[C@@H]1NC(=O)c1nc(Cl)c(CC)[nH]1,,C1CCOC1,,CO,[Li+].[OH-],test
US20140228357A1,CCOC(=O)COc1ccc(C23CC4CC(CC(C4)C2)C3)cc1C>>Cc1cc(C23CC4CC(CC(C4)C2)C3)ccc1OCC(=O)O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20070032515A1,CCOC(=O)COC.COc1ccc(CC#N)cc1OC>>COCC(=O)C(C#N)c1ccc(OC)c(OC)c1,,CCO,,C,C[O-].[Na+],test
US20130231328A1,COC(=O)C1(C)CCC(O)CC1.O=C(O)c1ccc([N+](=O)[O-])cc1>>COC(=O)C1(C)CCC(OC(=O)c2ccc([N+](=O)[O-])cc2)CC1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040220234A1,CC(C)(C)OC(=O)NCCC(O)C(F)(F)F>>CNCCC(O)C(F)(F)F,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150353553A1,COCCCOc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(Cl)cc1>>Cc1ccc(OCCCO)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(Cl)cc2)c1,,ClCCl,,C[Si](C)(C)I,,test
US20020019413A1,CI.Cc1nc2ncc(C(=O)NCc3ccc(Cl)cc3)c(O)c2cc1Br>>Cc1nc2c(cc1Br)c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn2C,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20120172333A1,CCOC(=O)c1c(NC(=O)CC#N)ccn1-c1ccc(-c2ccco2)cc1>>N#Cc1c(O)c2c(ccn2-c2ccc(-c3ccco3)cc2)[nH]c1=O,,C1CCOC1,,CO,[H-].[Na+],test
US20140080808A1,CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(C3(c4ccc(Br)cc4)CC3)n2CCS1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cn1cc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO[Si](C)(C)C(C)(C)C)C5)CC3)cc2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US04663453,CN1CCN(C(=O)Nc2cc(Br)ccc2N2CCc3ccccc32)CC1.O=C1CCC(=O)N1Br>>CN1CCN(C(=O)Nc2cc(Br)ccc2N2CCc3cc(Br)ccc32)CC1,,CN(C)C=O,,ClCCl,,test
US20070287738A1,CN(C)C=O.COC(OC)N(C)C.COCCOc1ccc(CC(=O)CC#N)cc1OC.COc1ccc(CN)cc1OC>>COCCOc1ccc(-c2cn(Cc3ccc(OC)c(OC)c3)cc(C#N)c2=O)cc1OC,,CN(C)C=O,Cc1ccccc1,,,test
US05700446,COC(=O)[C@H]1[C@@H](c2ccc(I)cc2)C[C@@H]2CC[C@H]1N2C>>CN1[C@H]2CC[C@@H]1[C@@H](CO)[C@@H](c1ccc(I)cc1)C2,,CCOCC,,[BH4-].[Li+],,test
US20140315917A1,Cn1cc(-c2cc(Oc3cc(F)c(N)cc3Br)ccn2)cn1.O=C(Cl)Cl.O=C1NCCN1C1CCOCC1>>Cn1cc(-c2cc(Oc3cc(F)c(NC(=O)N4CCN(C5CCOCC5)C4=O)cc3Br)ccn2)cn1,,ClCCl,O,c1ccncc1,,test
US20150344423A1,C1CCNCC1.CCOC(=O)c1cn(-c2cc(C(C)(C)C)cc(C3(C)CC3)c2)c(C(=O)O)c1C>>CCOC(=O)c1cn(-c2cc(C(C)(C)C)cc(C3(C)CC3)c2)c(C(=O)N2CCCCC2)c1C,,CN(C)C=O,O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US04453005,COC(=O)CCCC(C=O)=C(Cl)c1ccc(-c2ccccc2)cc1.O>>COC(=O)CCCC(C(=O)O)=C(Cl)c1ccc(-c2ccccc2)cc1,,CC(C)(C)O,O,[Na+].[O-]Cl,,test
US20140171390A1,CCOC(=O)C[C@@H]1CC[C@@H](C(CNC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)NCC(NC(=O)OC(C)(C)C)[C@@H]1CC[C@@H](CC(=O)O)CC1,,C1CCOC1,CO,[Na+].[OH-],,test
US05840732,CC(=O)CBr.Nc1cccc(Cl)n1>>Br.Cc1cn2c(Cl)cccc2n1,,CCO,,,,test
US04470988,CCOC(=O)CN1C(=O)C(N2C(=O)c3ccccc3C2=O)CCCc2ccccc21>>CCOC(=O)CN1C(=O)C(N)CCCc2ccccc21,,CCO,,NN,O,test
US20150148340A1,CCOC(=O)c1cn(-c2ccc3c(c2)ncn3C(C)C)c(=O)n(Cc2cccc(C(F)(F)F)c2C)c1=O>>Cc1c(Cn2c(=O)c(C(=O)O)cn(-c3ccc4c(c3)ncn4C(C)C)c2=O)cccc1C(F)(F)F,,CC(=O)O,,Cl,O,test
US06291460B1,Cc1cccnc1CO.Clc1nn2c(-c3cccnc3)nnc2cc1C1CCC1>>Cc1cccnc1COc1nn2c(-c3cccnc3)nnc2cc1C1CCC1,,CN(C)C=O,O,[H-].[Na+],,test
US20100267721A1,C1CCOC1.N#Cc1ccc(-c2ccc(CN3CCN(C4CCC4)CC3)nc2)cc1>>O=Cc1ccc(-c2ccc(CN3CCN(C4CCC4)CC3)nc2)cc1,,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US20080194617A1,CCCCOC(=O)Cl.Cc1nn(C)c(-n2ccc3cc(Cl)ccc32)c1CCON>>CCCCOC(=O)NOCCc1c(C)nn(C)c1-n1ccc2cc(Cl)ccc21,,C1CCOC1,,CCN(CC)CC,,test
US20100029687A1,CCOC(=O)CCC(=O)Cl.C[C@H](c1cccc2ccccc12)N(CC1CCNCC1c1cccc(F)c1)C(=O)OC(C)(C)C>>CCOC(=O)CCC(=O)N1CCC(CN(C(=O)OC(C)(C)C)[C@H](C)c2cccc3ccccc23)C(c2cccc(F)c2)C1,,CCN(CC)CC,,C1CCOC1,[Cl-].[NH4+],test
US20160264552A1,CC(C)(C)OC(=O)CBr.CNC/C=C/C(=O)Nc1ccc(CN2CCC(Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)CC2)cc1>>CN(C/C=C/C(=O)Nc1ccc(CN2CCC(Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)CC2)cc1)CC(=O)OC(C)(C)C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04025505,Cc1ccc([N+](=O)[O-])cc1N1C(=O)c2ccc(C(=O)N(C)C)cc2C1=O>>Cc1ccc(N)cc1N1C(=O)c2ccc(C(=O)N(C)C)cc2C1=O,[Ni],CCOC(C)=O,,[H][H],,test
US20050209249A1,COC(=O)c1cccc(C(=O)O)c1.CS(N)(=O)=O>>COC(=O)c1cccc(C(=O)NS(C)(=O)=O)c1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20090298883A1,CC(C)(C)OC(=O)NCCN1CCC(CN)CC1.O=C(Cl)c1ccc2c(c1)OC(F)(F)O2>>CC(C)(C)OC(=O)NCCN1CCC(CNC(=O)c2ccc3c(c2)OC(F)(F)O3)CC1,,C1CCOC1,CCOC(C)=O,ClCCl,O=C([O-])O.[Na+],test
US20080188493A1,C#CCCCC#N.CC(=O)OCC(C)C>>CC#CCC(C#N)C(C)=O,,CN(C)C=O,,O,CC(C)(C)[O-].[K+],test
US20080113966A1,CCOC(=O)CCCBr.N#CCc1cccc(F)c1F>>CCOC(=O)CCCC(C#N)c1cccc(F)c1F,,CN(C)C=O,,O,[H-].[Na+],test
US05200329,CCOC(=O)C=NCl.Cl.Nc1c(Cl)ccc(Cl)c1O>>ClCc1nc2c(Cl)ccc(Cl)c2o1,,ClCCl,,,,test
US20150232465A1,CC(=O)N1c2ccc(-c3cnn(C4CC4)c3)cc2NC[C@@H]1C.O=C(Cl)C1CC1>>CC(=O)N1c2ccc(-c3cnn(C4CC4)c3)cc2N(C(=O)C2CC2)C[C@@H]1C,,ClCCCl,,CCN(C(C)C)C(C)C,,test
US20030055081A1,CCOC(=O)c1cncn1C[C@H]1CC[C@H]2CN[C@H](C(=O)OCC)C[C@H]2C1.Cl.Cl>>CCOC(=O)c1cncn1C[C@H]1CC[C@H]2CN[C@H](C(=O)O)C[C@H]2C1.Cl.Cl,,Cl,,,,test
US20110071175A1,Fc1ccc(S)cc1.O=Cc1ccc(F)c(F)c1>>O=Cc1ccc(Sc2ccc(F)cc2)c(F)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150094328A1,COc1ccc2[nH]cc(C(=O)N[C@H]3CCCC[C@@H]3O)c2n1.Fc1ccc(CBr)cc1>>COc1ccc2c(n1)c(C(=O)N[C@H]1CCCC[C@@H]1O)cn2Cc1ccc(F)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090143361A1,COc1ccc(F)cc1B(O)O.COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)cc(Cl)c4)n3c2n1>>COc1ccc2nc(C)c3c(C)nc(-c4cc(F)ccc4OC)n3c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20080182854A1,CC(C)(C)OC(=O)c1cccc(CO)n1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)c1cccc(CCl)n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20050026971A1,Nc1ccc(N)cc1.O=C1C=CC(=O)O1>>Nc1ccc(N2C(=O)C=CC2=O)cc1,,C1CCOC1,,,,test
US20110263573A1,CS(=O)(=O)Cl.Clc1ccc2c(c1)CNCc1nnc([C@@H]3CC[C@@H](c4nsc5ccccc45)CC3)n1-2>>CS(=O)(=O)N1Cc2cc(Cl)ccc2-n2c(nnc2[C@@H]2CC[C@@H](c3nsc4ccccc34)CC2)C1,,ClCCl,,CCN(CC)CC,,test
US04507296,Cn1nnnc1Br.NCC(O)CCOc1cccc(CN2CCCCC2)c1>>Cn1nnnc1NCC(O)CCOc1cccc(CN2CCCCC2)c1,,CCO,,,,test
US05541324,CCC(=O)OC(=O)CC.c1ccc2c(c1)NCc1c(-c3noc(C4CC4)n3)ncn1-2>>CCC(=O)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2ccccc21,,C1CCOC1,,,,test
US20050245515A1,OCc1cc2cc(C(O)(C(F)(F)F)C(F)(F)F)ccc2n1Cc1ccccc1>>O=Cc1cc2cc(C(O)(C(F)(F)F)C(F)(F)F)ccc2n1Cc1ccccc1,O=[Mn]=O,Cc1ccccc1,,,,test
US20130059834A1,Cc1ccc2cncn2c1.II>>Cc1ccc2c(I)ncn2c1,,CCO,O,O=C([O-])O.[Na+],,test
US20040092737A1,CCOC(=O)c1ncn(Cc2ccc3c(c2)N(COC)c2nccnc2S3)c1C.N>>COCN1c2cc(Cn3cnc(C(N)=O)c3C)ccc2Sc2nccnc21,,C1CCOC1,,,,test
US04742057,Nc1nc(CN2CCC(c3c[nH]c4ccccc34)CC2)cs1.O=C(Cl)C1CC1>>O=C(Nc1nc(CN2CCC(c3c[nH]c4ccccc34)CC2)cs1)C1CC1,,ClCCl,,CCN(CC)CC,CN(C)C=O,test
US20120220575A1,N#Cc1ccccc1CN1CC2COCCN2c2nc(Cl)ncc21.O=S(=O)(O)O>>NC(=O)c1ccccc1CN1CC2COCCN2c2nc(Cl)ncc21,,CCOC(C)=O,,,,test
US20110015200A1,CS(=O)(=O)Cl.O=C1CC[C@H](CN(CCO)Cc2ccccc2)N1>>CS(=O)(=O)OCCN(Cc1ccccc1)C[C@H]1CCC(=O)N1,,CCO,ClCCl,,,test
US20160222033A1,CCOC(=O)C1CCC(Br)C1=O.NC(N)=S>>CCOC(=O)C1CCc2sc(N)nc21,,C1COCCO1,,,,test
US20160009712A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cn1c(=O)oc2cc(Br)c(F)cc21>>Cn1c(=O)oc2cc(B3OC(C)(C)C(C)(C)O3)c(F)cc21,,C1COCCO1,,ClCCl,CC(=O)[O-].[K+],test
US20090291967A1,CC(=O)CCl.CC(C)(C)c1ccc(C(=N)N)cc1>>Cc1cnc(-c2ccc(C(C)(C)C)cc2)[nH]1,,C1CCOC1,O,O=C([O-])O.[K+],,test
US20150166480A1,COC(=O)c1ccc(-c2cnc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)nc2)c(F)c1>>O=C(O)c1ccc(-c2cnc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)nc2)c(F)c1,,C1CCOC1,,O,[Li]O,test
US20050282808A1,CN(C)[C@@H]1CC[C@@H](C(=O)Nc2c(C(=O)Nc3ccc(Cl)cn3)oc3ccc(C(=O)O)cc23)CC1>>CN(C)[C@@H]1CC[C@@H](C(=O)Nc2c(C(=O)Nc3ccc(Cl)cn3)oc3ccc(CO)cc23)CC1,,O=S(Cl)Cl,,,,test
US20080207611A1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1ccncc1>>CC(C)(C)OC(=O)N1CCN(Cc2ccncc2)CC1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140066420A1,CC(C)(C)c1ccccc1OCC1CN(C(=O)CSc2nc[nH]n2)C1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)c1ccccc1OCC1CN(C(=O)CS(=O)c2nc[nH]n2)C1,,CCOC(C)=O,,O=S([O-])O.[Na+],,test
US04720500,Nc1ccc2ccc(Cl)nc2n1.O=C(O)Cc1ccccc1>>O=C(Cc1ccccc1)Nc1ccc2ccc(Cl)nc2n1,,O,,CC#N,,test
US04183933,C=O.CNC.Cc1cnc(C)cn1>>Cc1cnc(CCN(C)C)cn1,,O,,Cl,[Na+].[OH-],test
US20070100141A1,CCN(CC)C(=O)C(c1ccccc1)C1CCN(c2ccc(N)cc2F)CC1.Cc1noc(C)c1CC(=O)O>>CCN(CC)C(=O)C(c1ccccc1)C1CCN(c2ccc(NC(=O)Cc3c(C)noc3C)cc2F)CC1,,ClCCCl,O,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US04377580,CC(C)C(=O)Cl.CCOC(=O)C(=CNc1ncnc2ccc(N)cc12)C(=O)OCC>>CCOC(=O)C(=CNc1ncnc2ccc(NC(=O)C(C)C)cc12)C(=O)OCC,,ClCCl,,c1ccncc1,,test
US20070244140A1,CC(C)(C)OC(=O)N[C@H](COc1ccc(B2OC(C)(C)C(C)(C)O2)cc1)Cc1ccccc1.NS(=O)(=O)c1ccc(Nc2nccc(Cl)n2)cc1>>CC(C)(C)OC(=O)N[C@H](COc1ccc(-c2ccnc(Nc3ccc(S(N)(=O)=O)cc3)n2)cc1)Cc1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20100216798A1,Cc1ccc(OC2CCCCO2)cc1Nc1ccc2ncc(-c3ccncc3)n2n1>>Cc1ccc(O)cc1Nc1ccc2ncc(-c3ccncc3)n2n1,,CO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20040116353A1,N=C(c1ccccc1)c1ccccc1.NCc1cccnc1>>c1ccc(C(=NCc2cccnc2)c2ccccc2)cc1,,ClCCl,,,,test
US20060079535A1,N#CCCCCl.O=c1ccc2c(O)c3ccoc3cc2o1>>N#CCCCOc1c2ccoc2cc2oc(=O)ccc12,,CCC(C)=O,,[I-].[K+],,test
US20140271490A1,CCOCOc1cc(CO)cc(CO)c1.ClCCl.Clc1nnnc(Cl)c1Cl>>CCOCOc1cc(CCl)cc(CCl)c1,,CN(C)C=O,,,,test
US20080265746A1,Brc1ccc(-c2nc3ccccc3n2-c2ccccc2)cc1.c1ccc(-c2cc(-c3ccccc3)c3ccc4c(-c5ccccc5)ccnc4c3n2)cc1>>c1ccc(-c2cc(-c3ccccc3)c3ccc4c(-c5ccccc5)cc(-c5ccc(-c6nc7ccccc7n6-c6ccccc6)cc5)nc4c3n2)cc1,,C1CCOC1,,O,[Li]CCCC,test
US20140206618A1,Cc1c([C@H](O)CN2CCN(C(=O)OC(C)(C)C)C[C@H]2CO)ccc2c1COC2=O.O=C(Cl)OCc1ccccc1>>Cc1c([C@H](O)CN2CCN(C(=O)OCc3ccccc3)C[C@H]2CO)ccc2c1COC2=O,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20090036444A1,CC(=O)Nc1ccc(N2CCOCC2)c(COC(C)=O)c1.CI>>CC(=O)OCc1cc(N(C)C(C)=O)ccc1N1CCOCC1,,CN(C)C=O,,O,[H-].[Na+],test
US20070088165A1,CCOC(=O)c1cc(COCC(C)(Cc2ccccc2)NC(=O)OC(C)(C)C)cc(C2(C#N)CCCC2)c1>>CC(COCc1cc(C(=O)O)cc(C2(C#N)CCCC2)c1)(Cc1ccccc1)NC(=O)OC(C)(C)C,,C1CCOC1,O,[Li]O,,test
US20100121048A1,CC(=O)N(C)C.CCCCOC(=O)N1CCN(C(=O)c2ncn(C3CCNC3)c2-c2ccccc2)[C@H](Cc2ccccc2)C1.O=C(Cl)c1ccccc1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ncn(C3CCN(C(=O)c4ccccc4)C3)c2-c2ccccc2)[C@H](Cc2ccccc2)C1,,CC(=O)N(C)C,,O=C([O-])O.[Na+],,test
US05049699,C=O.O=C(O)CC(O)(CC(=O)O)C(=O)O>>O=C(O)CC1(CC(=O)O)OCOC1=O,,O,,,,test
US20090137595A1,Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1N.Cc1nc(Cl)sc1C(=O)O>>Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1NC(=O)c1sc(Cl)nc1C,CN(C)C=O,CC(=O)N(C)C,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US20110015173A1,COc1cnc2[nH]cc(-c3cc(Cl)nc(N[C@@H]4CC[C@@H](NC(=O)CCl)CC4)c3)c2c1.NC1CCCCC1>>COc1cnc2[nH]cc(-c3cc(Cl)nc(N[C@@H]4CC[C@@H](NC(=O)CNC5CCCCC5)CC4)c3)c2c1,,CN(C)C=O,,CCN(CC)CC,,test
US20090286783A1,O=S(=O)(Nc1cccc(CO)c1F)c1ccc(C(F)(F)F)cc1>>O=Cc1cccc(NS(=O)(=O)c2ccc(C(F)(F)F)cc2)c1F,,C1CCOC1,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20160122331A1,COC(=O)c1cccc([C@H]2C[C@H](N=[N+]=[N-])CCO2)c1>>COC(=O)c1cccc([C@H]2C[C@H](N)CCO2)c1,[Ni],O,,CO,,test
US20130267546A1,C=O.CCCCCCCCCCc1nc(N)nc(C)c1OCc1ccccc1.CO>>CCCCCCCCCCc1nc(N(C)C)nc(C)c1OCc1ccccc1,,CO,,[BH3-]C#N.[Na+],,test
US20080188460A1,COC(=O)c1cc(C#N)ccc1-c1ccc(Cl)cc1>>COC(=O)c1cc(CN)ccc1-c1ccc(Cl)cc1,Cl[Ni]Cl,CO,,[BH4-].[Na+],,test
US20130109661A1,COc1ccc(Nc2cc(N3CCC(C(=O)Nc4ccc(C(=O)OC(C)(C)C)cc4)C3)nn3ccnc23)nc1OC>>COc1ccc(Nc2cc(N3CCC(C(=O)Nc4ccc(C(=O)O)cc4)C3)nn3ccnc23)nc1OC,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020072528A1,CCCC(=O)Cl.Nc1cnc2cc(Cl)ccc2c1O>>CCCC(=O)Nc1cnc2cc(Cl)ccc2c1O,,C1CCOC1,,CCN(CC)CC,,test
US06159990,N#CC1(c2ccccc2)CCC(N2CCNCC2)CC1.O=C1OCC(c2ccc(F)c(F)c2)N1C(=O)Oc1ccc([N+](=O)[O-])cc1>>N#CC1(c2ccccc2)CCC(N2CCN(C(=O)N3C(=O)OCC3c3ccc(F)c(F)c3)CC2)CC1,,C1CCOC1,,CCCCCC,CCOC(C)=O,test
US20090054392A1,CC(C)(C)OC(=O)NC1CCCNCC1.Clc1nccc(-c2ccc3ccccc3c2)n1>>NC1CCCN(c2nccc(-c3ccc4ccccc4c3)n2)CC1,,CCOC(C)=O,CS(C)=O,CCN(C(C)C)C(C)C,,test
US20090082372A1,CNC(=O)c1ccc(C#Cc2ccc(OC(F)(F)F)c(C(=O)O)c2)cc1.NC(CO)Cc1n[nH]c2c(C(F)(F)F)cccc12>>CNC(=O)c1ccc(C#Cc2ccc(OC(F)(F)F)c(C(=O)NC(CO)Cc3n[nH]c4c(C(F)(F)F)cccc34)c2)cc1,CN(C)c1ccncc1,C1CCOC1,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140057914A1,CC(C(O)Cc1cccc(Br)c1)[N+](=O)[O-]>>CC(N)C(O)Cc1cccc(Br)c1,[Fe],CCO,,O,,test
US20080085890A1,CON=Cc1cccc2[nH]ccc12>>NCc1cccc2[nH]ccc12,[Pd],CCO,,Cl,,test
US20040220188A1,COC(=O)c1cc(I)ccc1NN.O=C1CC(=O)N(c2ccc(I)cc2)N1>>COC(=O)c1cc(I)ccc1N1NC(=O)CC1=O,,C1CCOC1,,CCOC(C)=O,Cl,test
US20160222033A1,CCN(Cc1cc(=O)n2c(CCO)c(C)sc2n1)c1ccc(F)cc1.CI>>CCN(Cc1cc(=O)n2c(CCOC)c(C)sc2n1)c1ccc(F)cc1,,C1CCOC1,,[H-].[Na+],,test
US20120283222A1,CC(=Cc1cnc(CO[Si](C)(C)C(C)(C)C)s1)C(=O)OC(C)(C)C>>CC(Cc1cnc(CO[Si](C)(C)C(C)(C)C)s1)C(=O)OC(C)(C)C,[Pd],CCO,,,,test
US20110105502A1,COc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)=NCC2>>Oc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)=NCC2,,Br,,,,test
US09193720B2,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc(C)c(Br)c1N1CCC(C)(C)CC1.OB(O)c1ccc(OCc2ccc(Cl)cc2)cc1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc(C)c(-c2ccc(OCc3ccc(Cl)cc3)cc2)c1N1CCC(C)(C)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20060189673A1,CC(C)(C)O.Cc1c(C)c([N+](=O)[O-])c(C)c2c1OC(C)(C=O)CC2>>Cc1c(C)c([N+](=O)[O-])c(C)c2c1OC(C)(C(=O)O)CC2,,CC(C)(C)O,O,CC=C(C)C,[Na+].[O-]Cl,test
US20060106096A1,COc1cc(N=C=O)cc(OC)c1OC.Cl.Nc1ccc2cc(C(=O)N[C@H]3CN4CCC3CC4)sc2c1>>COc1cc(NC(=O)Nc2ccc3cc(C(=O)N[C@H]4CN5CCC4CC5)sc3c2)cc(OC)c1OC.Cl,,C1CCOC1,,CCN(CC)CC,Cl,test
US20130274255A1,CN1CCN(c2ccc(-c3nn(COCC[Si](C)(C)C)c4c3Cc3sc(-c5cccnc5)cc3-4)cc2)CC1.Cl>>CN1CCN(c2ccc(-c3n[nH]c4c3Cc3sc(-c5cccnc5)cc3-4)cc2)CC1.Cl,,CO,,,,test
US20150152065A1,CC(N)c1ccccc1.O=[N+]([O-])c1ccccc1F>>CC(Nc1ccccc1[N+](=O)[O-])c1ccccc1,,CCO,,CCN(CC)CC,,test
US05550215,CC(C)(C)OC(=O)CBr.COc1cc(O)ccc1C=O>>COc1cc(OCC(=O)OC(C)(C)C)ccc1C=O,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04526897,Cc1ccc(C)c2c1C(=O)N(NC(=O)OC(C)(C)C)C2=O>>Cc1ccc(C)c2c1CN(NC(=O)OC(C)(C)C)C2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110306590A1,Clc1nccnc1Cl.OC1CCOCC1>>Clc1nccnc1OC1CCOCC1,,C1CCOC1,,[H-].[Na+],,test
US05789412,CN(CCCl)CCCl.Nc1cccc(O)c1>>CN1CCN(c2cccc(O)c2)CC1,,CCCCO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20050272784A1,CC(=O)Cl.COC(=O)c1nc(-c2ccc(C(F)(F)F)cc2)oc1-c1ccc(C(=N)NO)cc1>>COC(=O)c1nc(-c2ccc(C(F)(F)F)cc2)oc1-c1ccc(C(=N)NOC(C)=O)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080039445A1,C1CCNC1.CC#CCOc1ncnc(F)c1F>>CC#CCOc1ncnc(N2CCCC2)c1F,,Cc1ccccc1,,,,test
US06034248,O=[N+]([O-])c1ccc(F)cc1.c1c[nH]nn1>>O=[N+]([O-])c1ccc(-n2nccn2)cc1,,O,,,,test
US20080262050A1,C=CCBr.CCOC(C)=O.O=[N+]([O-])c1cc2c(O)noc2cc1O>>C=CCOc1cc2onc(OCC=C)c2cc1[N+](=O)[O-],,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05292732,CC1=NCCn2c1ccc2-c1ccccc1.CI>>CC1=[N+](C)CCn2c1ccc2-c1ccccc1.[I-],,CCO,,,,test
US20130096130A1,C=CCC[C@@H](c1cccc(F)c1F)[C@H](N)c1scnc1Br.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=CCC[C@@H](c1cccc(F)c1F)[C@H](NC(=O)OC(C)(C)C)c1scnc1Br,,ClCCl,,,,test
US20040053942A1,CN(C)CCCN.CS(=O)(=O)c1nccc(-c2c(-c3ccc(C(F)(F)F)cc3)nn3cc(C(F)(F)F)ccc23)n1>>CN(C)CCCNc1nccc(-c2c(-c3ccc(C(F)(F)F)cc3)nn3cc(C(F)(F)F)ccc23)n1,,O,,,,test
US20120004203A1,CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(N)nc2N1c1cccc(C(F)(F)F)c1.O=C(Cl)C1CC1>>CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(NC(=O)C3CC3)nc2N1c1cccc(C(F)(F)F)c1,,c1ccncc1,,Cl,,test
US20150038438A1,COc1ccc(Cn2c3c(c(O)c(C(=O)O)c2=O)CCN(C)c2cc(N4CCCC4)ccc2-3)c(OC)c1>>CN1CCc2c([nH]c(=O)c(C(=O)O)c2O)-c2ccc(N3CCCC3)cc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020103247A1,CC(C)(C)OC(=O)N1CCc2cc(C#CCCCO)ccc21>>CC(C)(C)OC(=O)N1CCc2cc(CCCCCO)ccc21,[Pd],CO,,,,test
US04171446,Cc1cc(O)c(C)c([N+](=O)[O-])c1.ClCc1ccccc1>>Cc1cc(OCc2ccccc2)c(C)c([N+](=O)[O-])c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06015774,Cn1c(C(F)(F)F)cnc(-c2ccc(F)c([N+](=O)[O-])c2)c1=O>>Cn1c(C(F)(F)F)cnc(-c2ccc(F)c(N)c2)c1=O,[Pd],CCOC(C)=O,,[H][H],,test
US20090181942A1,COc1cccc(C(=O)c2cc(Cl)ccc2NC(=O)C(C)(C)C)c1C>>COc1cccc(C(=O)c2cc(Cl)ccc2N)c1C,,CO,O,[K+].[OH-],,test
US20080058521A1,COc1ccc(-c2ccc(S(N)(=O)=O)cc2)cc1CN(C(=O)c1sc2c(F)ccc(F)c2c1Cl)C1CCC(N(C)C(=O)OC(C)(C)C)CC1.ClCCl>>CNC1CCC(N(Cc2cc(-c3ccc(S(N)(=O)=O)cc3)ccc2OC)C(=O)c2sc3c(F)ccc(F)c3c2Cl)CC1.Cl,,ClCCl,,COC(C)(C)C,,test
US20120190677A1,CC1(C)CC(c2cccc(N3CCCC3)c2)Nc2c(C(=O)O)cc(F)cc21.CS(N)(=O)=O>>CC1(C)CC(c2cccc(N3CCCC3)c2)Nc2c(C(=O)NS(C)(=O)=O)cc(F)cc21,CN(C)c1ccncc1,ClCCl,,,,test
US20140107118A1,C[C@@](CO[C@](C)(C(N)=O)C(F)(F)F)(NS(=O)(=O)c1ccc([N+](=O)[O-])cc1)c1nc(Br)ccc1F>>C[C@@](CO[C@](C)(C#N)C(F)(F)F)(NS(=O)(=O)c1ccc([N+](=O)[O-])cc1)c1nc(Br)ccc1F,,ClCCl,,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US20120190677A1,CC1(C)CC(c2ccc(F)c(Cl)c2)Nc2ccc(C(=O)O)nc21.CS(N)(=O)=O>>CC1(C)CC(c2ccc(F)c(Cl)c2)Nc2ccc(C(=O)NS(C)(=O)=O)nc21,,CN(C)C=O,O,O=C(n1ccnc1)n1ccnc1,[H-].[Na+],test
US20130096160A1,Brc1csc(Br)n1.C1CNCCN1>>Brc1csc(N2CCNCC2)n1,,C1COCCO1,O,,,test
US20040058820A1,CC(=O)C(Cc1ccc(Cl)cc1)C(=O)OCc1ccccc1.N>>CC(N)C(Cc1ccc(Cl)cc1)C(=O)OCc1ccccc1,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US20040147543A1,CC(C)(N)CNc1c([N+](=O)[O-])cnc2cc(-c3ccccc3)ccc12.O=C(Cl)C1CCCCC1>>C1CCCCC1.CC(C)(CNc1c([N+](=O)[O-])cnc2cc(-c3ccccc3)ccc12)NC=O,,ClCCl,,CCN(CC)CC,,test
US20120108574A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccc5c(c4)COC5=O)nc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1>>NC1(c2ccc(-c3c(-c4ccc5c(c4)COC5=O)nc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1,,CO,,C1COCCO1,Cl,test
US20040043969A1,COc1ccc2c(c1OC(C)=O)CCCC2.O=C1CCCc2ccccc21>>COc1ccc2c(c1O)CCCC2=O,,C1COCCO1,O,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20110003807A1,C[Si](C)(C)N[Si](C)(C)C.N#Cc1sc(Br)nc1-c1ccc(Cl)cc1Cl>>N=C(N)c1sc(Br)nc1-c1ccc(Cl)cc1Cl,,C1CCOC1,CCOCC,Cl,[Li]CCCC,test
US08507520B2,Cc1c(-c2ccc(F)cc2F)nc2ccc(-c3cccc(CO[Si](C)(C)C(C)(C)C)c3)cn12>>Cc1c(-c2ccc(F)cc2F)nc2ccc(-c3cccc(CO)c3)cn12,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150057286A1,Cc1cccc2cc[nH]c12.Fc1cc(F)nc(F)c1>>Cc1cccc2ccn(-c3cc(F)nc(F)c3)c12,,CS(C)=O,ClCCl,CC(C)(C)[O-].[K+],,test
US20080153812A1,CCN1CCCNCC1.COc1cc(CCc2cc(NC(=O)c3cnc(Cl)cn3)[nH]n2)cc(OC)c1>>CCN1CCCN(c2cnc(C(=O)Nc3cc(CCc4cc(OC)cc(OC)c4)n[nH]3)cn2)CC1,,CO,CS(C)=O,,,test
US04198347,CC(C)=C=CBr.CCOC(=O)CC#N>>C#CC(C)(C)C(C#N)C(=O)OCC,,CCO,,O,[Na],test
US20070093483A1,CCOC(=O)Cc1cc(OC)ccc1OC.NNC(=S)Nc1ccc(S(=O)(=O)N2CCCCC2)cc1>>COc1ccc(OC)c(Cc2n[nH]c(=S)n2-c2ccc(S(=O)(=O)N3CCCCC3)cc2)c1,,CO,,C[O-].[Na+],,test
US20140194406A1,COc1cc(C(=O)N2CCN(C)CC2)ccc1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1cc(C(=O)N2CCN(C)CC2)ccc1OS(=O)(=O)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US20130096120A1,Cc1c(I)ccnc1F.OCC12CC3CC(CC(C3)C1)C2>>Cc1c(I)ccnc1OCC12CC3CC(CC(C3)C1)C2,,C1CCOC1,,[H-].[Na+],,test
US20100167931A1,CCOC(=O)C(C(=O)OCC)c1ncc(Cl)cc1Cl.COC(=O)c1c[nH]nc1N>>COC(=O)c1cnn2c(O)c(-c3ncc(Cl)cc3Cl)c(O)nc12,,CCO,,CCCCN(CCCC)CCCC,,test
US04820838,CCOc1ccc(CC2=[NH+]CCc3cc(OCC)c(OCC)cc32)cc1OCC.Cn1c(=O)c2c(ncn2CC(=O)[O-])n(C)c1=O>>CCOc1ccc(CC2=[NH+]CCc3cc(OCC)c(OCC)cc32)cc1OCC.Cn1c(=O)c2c(ncn2CC(=O)[O-])n(C)c1=O,,CC(C)=O,,O,,test
US04012513,COc1ccc2c(c1)c(CC(=O)O)c(C)n2-c1ncnc2cc(Cl)ccc12.Oc1ccccc1>>COc1ccc2c(c1)c(CC(=O)Oc1ccccc1)c(C)n2-c1ncnc2cc(Cl)ccc12,,COCCOC,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20030216374A1,CC(=O)NC[C@H]1CN(c2ccc(C3=CC(CSc4ncccn4)N(C(c4ccccc4)(c4ccccc4)c4ccccc4)C3)cc2)C(=O)O1>>CC(=O)NC[C@H]1CN(c2ccc(C3=CC(CSc4ncccn4)NC3)cc2)C(=O)O1,,CC(C)=O,O,Cl,Cl,test
US20160158207A1,CN1CCN(c2nn(C3CCOCC3)c3c2CNCC3)c2cc(C(F)(F)F)c(-c3cnn(C)c3)cc21.CNC(=O)n1ccnc1>>CNC(=O)N1CCc2c(c(N3CCN(C)c4cc(-c5cnn(C)c5)c(C(F)(F)F)cc43)nn2C2CCOCC2)C1,,ClCCl,,CCN(CC)CC,,test
US20100081692A1,C[C@@]1(COS(=O)(=O)c2cccc([N+](=O)[O-])c2)CO1.N#Cc1ccccc1O.N#Cc1ccccc1OC[C@@H]1CO1>>CC(Oc1ccccc1C#N)[C@@H]1CO1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US03950307,O=C(Cl)c1c(Br)c(Br)c(Br)c(Br)c1Br.O=C1NC(=O)c2c(Br)c(Br)c(Br)c(Br)c21>>O=C(c1c(Br)c(Br)c(Br)c(Br)c1Br)N1C(=O)c2c(Br)c(Br)c(Br)c(Br)c2C1=O,,C1COCCO1,,[K],,test
US04410716,CCO.O=C(O)Cc1ccc2c(c1)Cc1ccccc1CC2=O>>CCOC(=O)Cc1ccc2c(c1)Cc1ccccc1CC2=O,,Cl,,,,test
US04532236,CC(C)(C)[Si](C)(C)OC[C@H]1[C@H](OC(=O)c2ccccc2)C[C@@H]2OC(=O)C[C@@H]21>>CC(C)(C)[Si](C)(C)OC[C@H]1[C@H](O)C[C@@H]2OC(=O)C[C@@H]21,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US04778803,COC(=O)c1cc(O)cs1.ClCc1ccccn1>>COC(=O)c1cc(OCc2ccccn2)cs1,,CCC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20110178089A1,O=C(O)c1cnccc1Oc1cc(Cl)ccc1Cl.c1ccc2c(c1)CCCN2>>O=C(c1cnccc1Oc1cc(Cl)ccc1Cl)N1CCCc2ccccc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06355641B1,C(=NCC1CCNCC1)c1ccccc1.CCOC=C1N=C(c2cccc3ccccc23)OC1=O>>O=C1OC(c2cccc3ccccc23)=NC1=CN1CCC(CN=Cc2ccccc2)CC1,,C1CCOC1,,,,test
US20010027196A1,CSc1nc(N)nc(Br)c1C#N.Clc1cn[nH]c1>>CSc1nc(N)nc(-n2cc(Cl)cn2)c1C#N,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040077662A1,CCOC(=O)CC#N.CCOC(C)(OCC)OCC>>CCOCC=C(C#N)C(=O)OCC,CC(=O)O,,,,,test
US05804532,CSc1cc(C(=O)c2cnoc2C2CC2)ccc1C>>CSc1cc(C(=O)C(C#N)C(=O)C2CC2)ccc1C,,ClCCl,,CCN(CC)CC,Cl,test
US20160168090A1,O=C(c1c[nH]c2cccc(Cl)c12)C(F)(F)F.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>O=C(c1cn(CC(F)(F)F)c2cccc(Cl)c12)C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100048564A1,CC(C)(C)OC(=O)NCc1cc(Cl)ccc1[N+](=O)[O-].COc1ccc(F)c(O)c1>>COc1ccc(F)c(Oc2ccc([N+](=O)[O-])c(CNC(=O)OC(C)(C)C)c2)c1,,CN(C)C=O,,[H-].[Na+],,test
US20120196894A1,C=CCCOC1CCCCC1O>>C=CCCOC1CCCCC1=O,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US05017724,Cc1ccc(O)c2c1C1CCCCC1C2=O.O=[N+]([O-])O>>Cc1cc([N+](=O)[O-])c(O)c2c1C1CCCCC1C2=O,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20160068559A1,CC1(C)O[C@@H]2[C@H](O1)[C@@H](CSCCCCc1nc3cc(C(C)(C)C)ccc3n1COCC[Si](C)(C)C)O[C@H]2n1cnc2c(N)ncnc21.O=C(O)C(F)(F)F>>CC(C)(C)c1ccc2[nH]c(CCCCS(=O)C[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)nc2c1,,O,,,,test
US20090012097A1,COC(=O)C(C)(C)Br.Oc1ccc2cnccc2c1>>COC(=O)C(C)(C)Oc1ccc2cnccc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160229814A1,CC(C)n1c(=O)n(CC2CC2)c(=O)c2cc([N+](=O)[O-])ccc21>>CC(C)n1c(=O)n(CC2CC2)c(=O)c2cc(N)ccc21,[Pd],C1CCOC1,,CO,[H][H],test
US20110275797A1,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(O)ccc1OCc1ccccc1.CN1CCN(CCCBr)CC1>>CN1CCN(CCCOc2ccc(OCc3ccccc3)c(C(=O)Nc3cc(-c4ccccc4)ccc3C(=O)OC(C)(C)C)c2)CC1,,ClC(Cl)Cl,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100292253A1,CSc1nc(-c2cccnc2)sc1[N+](=O)[O-]>>CSc1nc(-c2cccnc2)sc1N,[Pd],CCOC(C)=O,,CC(=O)O,[H][H],test
US20100152165A1,CC(=O)OC(C)=O.CCCN1CCCc2cccc(NCc3ccc(CCC(=O)OCC)c(F)c3)c21>>CCCN1CCCc2cccc(N(Cc3ccc(CCC(=O)OCC)c(F)c3)C(C)=O)c21,,c1ccncc1,,O=C(O)CC(O)(CC(=O)O)C(=O)O,,test
US20120035196A1,Cc1cc(O)cc(C)c1-c1cccc(C=O)c1C.O=C(OCCBr)c1ccccc1>>Cc1cc(OCCOC(=O)c2ccccc2)cc(C)c1-c1cccc(C=O)c1C,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20070043020A1,CCn1cc(C(=O)Cl)c(NS(=O)(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)n1.N>>CCn1cc(C(N)=O)c(NS(=O)(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)n1,,CCOC(C)=O,ClCCl,,,test
US20150299190A1,Nc1cc([N+](=O)[O-])ccc1Cl.O=C(O)c1nccs1>>O=C(Nc1cc([N+](=O)[O-])ccc1Cl)c1nccs1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160264567A1,O=C1c2ccccc2C(=O)N1Cc1cc(C2=CCC(C(F)(F)F)CC2)c(F)cn1>>NCc1cc(C2=CCC(C(F)(F)F)CC2)c(F)cn1,,CO,,NN,O,test
US05025025,CCOC(=O)C(CCCCCCNS(=O)(=O)c1ccc(Cl)cc1)(CCCCCc1cccnc1)C(=O)OCC>>O=C(O)C(CCCCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCCCc1cccnc1,,CC(=O)O,Cl,O,O=C([O-])O.[Na+],test
US04920120,Cc1c(F)c(F)c(F)c(F)c1C(=O)O.O=C(Cl)C(=O)Cl>>Cc1c(F)c(F)c(F)c(F)c1C(=O)Cl,CN(C)C=O,ClCCl,,,,test
US20110053902A1,C[C@]12CC[C@@H](OC=O)CC1C(=O)C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12>>C[C@]12CC[C@@H](O)CC1C(=O)C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US06713473B1,CC(C)n1c2c(c3cc(N)ccc31)CCCC2.O=C(Cl)Oc1ccccc1>>CC(C)n1c2c(c3cc(NC(=O)Oc4ccccc4)ccc31)CCCC2,,ClCCl,,CCN(CC)CC,,test
US20110172224A1,CN1CCNCC1.Cc1cccc(COc2ccc(Nc3ncnc4sc5c(c34)CCc3nn(CCOS(C)(=O)=O)cc3-5)cc2Cl)n1>>Cc1cccc(COc2ccc(Nc3ncnc4sc5c(c34)CCc3nn(CCN4CCN(C)CC4)cc3-5)cc2Cl)n1,,CC#N,,CCN(C(C)C)C(C)C,,test
US04836844,CC1=C(C)C(=O)OC1=O.Nc1nc2ccc(OC(F)(F)F)cc2s1>>CC1=C(C)C(=O)N(c2nc3ccc(OC(F)(F)F)cc3s2)C1=O,,CCCCCC,,c1ccc(Oc2ccccc2)cc1,,test
US20090324581A1,Cc1c(O)ccc2c1CCN2C(=O)OC(C)(C)C.FC(F)(F)c1cc(CCl)ccc1C1CC1>>Cc1c(OCc2ccc(C3CC3)c(C(F)(F)F)c2)ccc2c1CCN2C(=O)OC(C)(C)C,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20020169200A1,COC(=O)C=Cn1ccc2cc(CCc3cc4cccnc4nc3C)ccc21>>COC(=O)CCn1ccc2cc(CCc3cc4c(nc3C)NCCC4)ccc21,[Pd],CO,,,,test
US20080207654A1,CCCCc1nc(C)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.ClCc1csc(-c2ccccc2)n1>>CCCCc1nc(C)n(Cc2csc(-c3ccccc3)n2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05981775,COC(OC)N(C)C.COc1ccc(CC(=O)c2ccc(O)cc2O)cc1>>COc1ccc(-c2coc3cc(O)ccc3c2=O)cc1,,c1ccccc1,,,,test
US20100267666A1,CC(C)(C)OC(=O)N1CCN(c2ccc(-c3cnc4[nH]cc(C(=O)C5(C)CCCCC5)c4n3)cc2)CC1>>CC1(C(=O)c2c[nH]c3ncc(-c4ccc(N5CCNCC5)cc4)nc23)CCCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04900743,CSc1nnc(-c2ccc3ccccc3c2)n1C.O=C(OO)c1cccc(Cl)c1>>Cn1c(-c2ccc3ccccc3c2)nnc1S(C)=O,,ClCCl,,,,test
US06610694B1,CCOC(=O)CNC(=O)c1nnc2ccc(NCCCN3CCC(OC(c4ccccc4)c4ccccc4)CC3)nn12>>O=C(O)CNC(=O)c1nnc2ccc(NCCCN3CCC(OC(c4ccccc4)c4ccccc4)CC3)nn12,,CCO,,[Na+].[OH-],,test
US20050288273A1,Nc1ccc2c(c1)CCCC2=O.O=C(Cl)OCc1ccccc1>>O=C(Nc1ccc2c(c1)CCCC2=O)OCc1ccccc1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US06153768,C#CCCCCCCCO[Si](C)(C)C(C)(C)C.COCOc1ccc(C2(C)COc3cc(OCOC)ccc3C2=O)cc1>>COCOc1ccc(C2(C)COc3cc(OCOC)ccc3C2(O)C#CCCCCCCCO[Si](C)(C)C(C)(C)C)cc1,,C1CCOC1,,[Li]CCCC,,test
US20040053908A1,CCOC(=O)c1cc2c(Oc3ccc(NC(=O)Nc4ccc(F)cc4)cc3)ncnc2[nH]1>>O=C(Nc1ccc(F)cc1)Nc1ccc(Oc2ncnc3[nH]c(CO)cc23)cc1,,O,,C1CCOC1,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US04198422,CC(C)CSc1ccc2cc([N+](=O)[O-])c(N)cc2c1.O=C(OO)c1cccc(Cl)c1>>CC(C)CS(=O)c1ccc2cc([N+](=O)[O-])c(N)cc2c1,,ClC(Cl)Cl,,,,test
US06489324B2,C1CCNCC1.O=C(NOC1CCCCO1)[C@H]1CN(S(=O)(=O)CCCCl)CCN1S(=O)(=O)c1ccc(-c2ccc(F)cc2)s1>>O=C(NOC1CCCCO1)[C@H]1CN(S(=O)(=O)CCCN2CCCCC2)CCN1S(=O)(=O)c1ccc(-c2ccc(F)cc2)s1,,CN(C)C=O,,[I-].[K+],,test
US20070232583A1,CC(C)(C)NS(=O)(=O)c1ccc(-c2cn(-c3nc(-c4ccc(F)cc4)cc(C(F)(F)F)n3)cn2)s1>>NS(=O)(=O)c1ccc(-c2cn(-c3nc(-c4ccc(F)cc4)cc(C(F)(F)F)n3)cn2)s1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06204264B1,CCCCCCCCCCCCCCCCCCCCCc1nc2cc(C(=O)NC)ccc2n1CCCN(C)C.Cl>>CCCCCCCCCCCCCCCCCCCCCc1nc2cc(C(=O)NC)ccc2n1CCCN(C)C.Cl,,CCO,CCOC(C)=O,,,test
US20060128685A1,C=O.COc1ccc(-n2nc(C(=O)N3CC(C)NC(C)C3)cc2-c2ccccc2)cn1>>COc1ccc(-n2nc(C(=O)N3CC(C)N(C)C(C)C3)cc2-c2ccccc2)cn1,,CCO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20090069288A1,CC(C)Oc1ccc(-c2cc(C(=O)Nc3ccc(OCC4CO4)cc3)no2)cc1Cl.N>>CC(C)Oc1ccc(-c2cc(C(=O)Nc3ccc(OCC(O)CN)cc3)no2)cc1Cl,,C1CCOC1,,,,test
US20070072885A1,Cc1cc([N+](=O)[O-])ccc1Oc1ccc(CO)[n+]([O-])c1>>Cc1cc(N)ccc1Oc1ccc(CO)[n+]([O-])c1,O=[Pt]=O,CCOC(C)=O,,,,test
US20100063054A1,CCOC(=O)C(C)c1ccc(Cl)nn1.CI>>CCOC(=O)C(C)(C)c1ccc(Cl)nn1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20150197509A1,N#Cc1cc(N2CCC(F)(F)CC2)ncn1>>NCc1cc(N2CCC(F)(F)CC2)ncn1,[Pd],CO,,Cl,,test
US20150175557A1,CC(=O)Cl.NCCc1cccc(Cl)c1>>CC(=O)NCCc1cccc(Cl)c1,,ClCCl,,,,test
US20100093748A1,CC(C)(C)OC(=O)N1C(=O)n2c(nc3c(O)cccc32)C12CCN(c1ncnc3c1ccn3C(=O)OC(C)(C)C)CC2.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1C(=O)n2c(nc3c(OS(=O)(=O)C(F)(F)F)cccc32)C12CCN(c1ncnc3c1ccn3C(=O)OC(C)(C)C)CC2,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100063068A1,CC(C)(NC(=O)c1cccc(-c2ccncc2[N+](=O)[O-])c1)c1ccccc1>>CC(C)(NC(=O)c1cccc(-c2ccncc2N)c1)c1ccccc1,[Pd],CO,,,,test
US20100144722A1,COC(CN)OC.O=C(O)C1(c2ccc([N+](=O)[O-])cc2)CCC1>>COC(CNC(=O)C1(c2ccc([N+](=O)[O-])cc2)CCC1)OC,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120289738A1,CC(=O)O.FC(F)=C(F)CCBr>>CC(=O)OCCC(F)=C(F)F,,CC(=O)O,,O,CC(=O)[O-].[Na+],test
US20160272637A1,CCOC(=O)c1cn2ccc([N+](=O)[O-])cc2n1>>CCOC(=O)c1cn2ccc(N)cc2n1,[Pd],CCO,,,,test
US20110144105A1,CC(=O)c1ccc(C(=CC2CCCC2)c2cc3cccnc3n2S(=O)(=O)c2ccccc2)cc1.CC(C)[Mg]Cl>>CC(C)C(C)(O)c1ccc(C(=CC2CCCC2)c2cc3cccnc3n2S(=O)(=O)c2ccccc2)cc1,,C1CCOC1,,,,test
US20150166564A1,COCCBr.O=C(Nc1c2c(nn1-c1ccccc1)CCC2)N[C@@H]1CNC[C@H]1c1cccc(F)c1>>COCCN1C[C@@H](NC(=O)Nc2c3c(nn2-c2ccccc2)CCC3)[C@H](c2cccc(F)c2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20120184553A1,Nc1cncc(F)c1.O=C(O)c1cc(Br)ccc1OCc1ccccc1>>O=C(Nc1cncc(F)c1)c1cc(Br)ccc1OCc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060183736A1,COc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(S(C)(=O)=O)cc3)ccc2c1>>COc1ccc2c(C(O)c3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(S(C)(=O)=O)cc3)ccc2c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100261698A1,C1CCOC1.C[Si](C)(C)[N-][Si](C)(C)C.Cc1c(-c2cccnc2)[nH]c2ccccc12.N#Cc1cccc(C(=O)Cl)c1>>Cc1c(-c2cccnc2)n(C(=O)c2cccc(C#N)c2)c2ccccc12.[NH4+].[OH-],,C1CCOC1,,Cl,,test
US20040147561A1,CCOC(=O)c1cc(-c2csc(-c3ccnc(NCc4ccc(OC)cc4)c3)n2)c(=O)[nH]c1C>>CCOC(=O)c1cc(-c2csc(-c3ccnc(N)c3)n2)c(=O)[nH]c1C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070249670A1,CCCCOC[C@H](NC(=O)c1cc2ccccc2cc1N)C(=O)OC.Cc1cc(C)c(N=C=O)c(C)c1>>CCCCOC[C@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(C)cc1C)C(=O)OC,,c1ccncc1,,,,test
US20060264415A1,CC(C)(C)OC(=O)N1CC(CCCCI)C1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1CC(CCCCN=[N+]=[N-])C1,,CS(C)=O,,O,,test
US20050282808A1,CC(C)(C)O.O=C(Nc1ccc(Cl)cn1)c1oc2cccc(C(=O)O)c2c1NC(=O)[C@@H]1CC[C@@H](N2CCCC2=O)CC1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)Nc1cccc2oc(C(=O)Nc3ccc(Cl)cn3)c(NC(=O)[C@@H]3CC[C@@H](N4CCCC4=O)CC3)c12,,O=C([O-])O,[Na+],CCN(CC)CC,,test
US20060094776A1,CC(=O)Oc1cc([N+](=O)[O-])cc2c1OC(C)(C)C2>>CC(=O)Oc1cc(N)cc2c1OC(C)(C)C2,[Pd],CCO,,,,test
US20110175089A1,C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4CCCC[C@]4(C)[C@H]3CC[C@]12C.O=C(Cl)C(=O)Cl>>C[C@H](CCC(=O)Cl)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4CCCC[C@]4(C)[C@H]3CC[C@]12C,,ClCCl,,,,test
US04046900,CC(=O)N1CCC(C(=O)Cl)CC1.Cc1cccc(F)c1>>CC(=O)N1CCC(C(=O)c2ccc(C)cc2F)CC1,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100311693A1,CNS(C)(=O)=O.N#Cc1ccccc1CBr>>CN(Cc1ccccc1C#N)S(C)(=O)=O,,CC(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US05705691,N.O=C(Cl)c1cccc(Oc2ccc(C(F)(F)F)c(Cl)c2)c1>>NC(=O)c1cccc(Oc2ccc(C(F)(F)F)c(Cl)c2)c1,,Cc1ccccc1,,,,test
US20100305116A1,CCN(C(C)C)C(C)C.ClCCl.N[C@@H](CO)C(=O)N1CCOCC1.O.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CO.ClCCl.N.O=C1N[C@H](C(=O)N2CCOCC2)CO1,,ClCCl,,Cl,,test
US20070254869A1,CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)(C)C)c2cc(Cl)ccc21>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCNc2cc(Cl)ccc21,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20140242028A1,N#Cc1ccc(Sc2c(Cl)cc(N)cc2Cl)cc1.S=C(n1ccnc1)n1ccnc1>>N#Cc1ccc(Sc2c(Cl)cc(N=C=S)cc2Cl)cc1,,ClCCl,,,,test
US20050038035A1,Cc1ccc(-c2ccc(C(F)(F)F)cc2)c(C(=O)Nc2ccc(OCCc3cccc(NC(=O)OC(C)(C)C)n3)cc2)c1>>Cc1ccc(-c2ccc(C(F)(F)F)cc2)c(C(=O)Nc2ccc(OCCc3cccc(N)n3)cc2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04521430,CCCN(C)CCN1C(=O)[C@H](O)[C@H](c2ccc(OC)cc2)Sc2ccccc21.O=C(Cl)c1ccc(Cl)cc1[N+](=O)[O-].O=C([O-])C(=O)[O-]>>CCCN(C)CCN1C(=O)[C@H](OC(=O)c2ccc(Cl)cc2[N+](=O)[O-])[C@H](c2ccc(OC)cc2)Sc2ccccc21.O=C(O)C(=O)O,,ClCCl,,CCN(CC)CC,,test
US20110124634A1,CSc1nc(Cl)c(N)c(OCc2ccccc2)n1.Cc1ccc(S(=O)(=O)Cl)cc1>>CSc1nc(Cl)c(NS(=O)(=O)c2ccc(C)cc2)c(OCc2ccccc2)n1,,C1CCOC1,,[Li]CCCC,,test
US05447957,COC(=O)c1ccc(OC)cc1Oc1ccc(C(F)(F)F)cc1N>>COc1ccc(C(=O)O)c(Oc2ccc(C(F)(F)F)cc2N)c1,,C1CCOC1,,[Na+].[OH-],,test
US20100056521A1,CCOC(=O)c1ccc(-n2cc(C#N)c3cc(F)c(F)cc32)cc1OCOC>>CCOC(=O)c1ccc(-n2cc(C#N)c3cc(F)c(F)cc32)cc1O,,CCO,,C1CCOC1,Cl,test
US20130240799A1,CCCCCCCCCCCCN.O=C(Cl)c1ccc2c(=O)oc(-c3ccccc3)nc2c1>>CCCCCCCCCCCCNC(=O)c1ccc2c(=O)oc(-c3ccccc3)nc2c1,,C1CCOC1,,CCN(CC)CC,,test
US20160207905A1,CN1CCC(n2cc(Nc3ncc(Cl)c(N(C)c4cccc([N+](=O)[O-])c4)n3)cn2)CC1>>CN1CCC(n2cc(Nc3ncc(Cl)c(N(C)c4cccc(N)c4)n3)cn2)CC1,[Ni],CCO,ClCCl,,,test
US20100093730A1,O=C(O)CN1CCCC(c2ccccc2)(c2ccccc2)C1=O.c1ccc(C2(c3ccccc3)CNCCO2)cc1>>O=C(CN1CCCC(c2ccccc2)(c2ccccc2)C1=O)N1CCOC(c2ccccc2)(c2ccccc2)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040242659A1,NCCc1nccn1CCCCc1ccc(OCc2coc(/C=C/c3ccc(C(F)(F)F)cc3)n2)cc1.O=S(=O)(Cl)CC(F)(F)F>>O=S(=O)(CC(F)(F)F)NCCc1nccn1CCCCc1ccc(OCc2coc(/C=C/c3ccc(C(F)(F)F)cc3)n2)cc1,,C1CCOC1,,CCN(CC)CC,O,test
US20100087417A1,CCc1cc(-c2noc(-c3cc(C)nc(N(CC)CC)c3)n2)cc(C)c1OCCNC(=O)CNC(=O)OC(C)(C)C>>CCc1cc(-c2noc(-c3cc(C)nc(N(CC)CC)c3)n2)cc(C)c1OCCNC(=O)CN,,CCOC(C)=O,ClCCl,O=C(O)C(F)(F)F,,test
US05488118,COC(=O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1.CS(=O)(=O)Cl>>COC(=O)[C@H](OS(C)(=O)=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,O,test
US20110028738A1,Cc1sc2ccccc2c(=O)c1I.OB(O)c1ccccc1>>Cc1sc2ccccc2c(=O)c1-c1ccccc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20050032873A1,CC(=O)Oc1c(C)oc2ccccc12>>O=C(O)Cc1coc2ccccc12,,CCOC(C)=O,,CCO,[Na+].[OH-],test
US05476860,COc1ccc(C(=O)COc2ccc(C(=O)O)c(O)c2)cc1C12CC3CC(CC(C3)C1)C2>>COc1ccc(C(O)COc2ccc(C(=O)O)c(O)c2)cc1C12CC3CC(CC(C3)C1)C2,[Pd],C1COCCO1,,,,test
US20120184542A1,CN1CCN(CCNc2ncc3cc(C(=O)Nc4cc(C(=O)NC(CNC(=O)OC(C)(C)C)c5ccccc5)ccc4Cl)c(=O)[nH]c3n2)CC1.Cl>>CN1CCN(CCNc2ncc3cc(C(=O)Nc4cc(C(=O)NC(CN)c5ccccc5)ccc4Cl)c(=O)[nH]c3n2)CC1.Cl,,C1COCCO1,,,,test
US20070099925A1,Fc1ccc(-c2nc3cnccn3c2Br)cc1.OB(O)c1ccncc1>>Fc1ccc(-c2nc3cnccn3c2-c2ccncc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Cs+].[Cs+],test
US04666835,C=C[C@@]1(C)S[C@@H]2[C@H](N)C(=O)N2C1C(=O)O.O=C(Cl)COc1ccccc1>>C=C[C@@]1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2C1C(=O)O,,CC(C)=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US05013758,CC#CCC(C)C(=O)CP(=O)(OC)OC.O=C1CCC(=O)N1Br.O=C[C@H]1[C@H](OC(=O)c2ccccc2)C[C@@H]2CC3(C[C@@H]21)OCCO3>>CC#CCC(C)C(=O)C(Br)=C[C@H]1[C@H](OC(=O)c2ccccc2)C[C@@H]2CC3(C[C@@H]21)OCCO3,,COCCOC,,[H-].[Na+],[Cl-].[NH4+],test
US20030229125A1,N#Cc1cccc(Oc2cccc(C(F)(F)F)c2)n1>>NCc1cccc(Oc2cccc(C(F)(F)F)c2)n1,,CC(=O)O,,[H][H],,test
US20160221945A1,CC(C)(C)OC(=O)N1CC[C@H](F)[C@H]1C(=O)NCc1cc(-c2ccc(C(F)(F)F)nc2)ncc1C(N)=O>>CC(C)(C)OC(=O)N1CC[C@H](F)[C@H]1C(=O)NCc1cc(-c2ccc(C(F)(F)F)nc2)ncc1C#N,,ClCCl,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US20100286210A1,COc1cc(Cn2c3ccccc3c3c(OC(C(=O)Cl)c4ccccc4)cccc32)ccc1OCc1nc(-c2ccccc2)oc1C.O=C1N[C@@H](Cc2ccccc2)CO1>>COc1cc(Cn2c3ccccc3c3c(OC(C(=O)N4C(=O)OC[C@@H]4Cc4ccccc4)c4ccccc4)cccc32)ccc1OCc1nc(-c2ccccc2)oc1C,,C1CCOC1,,O,[Li]CCCC,test
US06057451,Nc1nc(-c2ccc(NC(=O)CNCc3ccccc3)cc2)cs1.O=C(O)C1CCCCC1>>Nc1nc(-c2ccc(NC(=O)CN(Cc3ccccc3)C(=O)C3CCCCC3)cc2)cs1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20140114067A1,COC(=O)c1ccc(Cn2c(Cc3c(Cl)cccc3Cl)nc3ccccc32)cc1>>O=C(O)c1ccc(Cn2c(Cc3c(Cl)cccc3Cl)nc3ccccc32)cc1,CO,O,,C1CCOC1,[Li+].[OH-],test
US20150353553A1,C[C@@H]1CC[C@@H](Cn2c(C(=O)c3ccccc3)nc3nc(C#N)nc(N[C@H](C)C4CCC4)c32)CC1.NO>>C[C@@H]1CC[C@@H](Cn2c(C(=O)c3ccccc3)nc3nc(C(=N)NO)nc(N[C@H](C)C4CCC4)c32)CC1,,CCO,O,Cl,O=C([O-])O.[Na+],test
US03931205,O=c1c2cc(CBr)ccc2oc2ncccc12.[C-]#N>>N#CCc1ccc2oc3ncccc3c(=O)c2c1,,O,,CN(C)C=O,,test
US20030096981A1,COc1nc(NC=O)nc2c1c(I)cn2[C@H]1C[C@H](OC(=O)C(C)C)[C@@H](COC(=O)C(C)C)O1>>Nc1nc2c(c(I)cn2[C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1,,CC#N,,,,test
US20080153813A1,COCc1cnc2ccc(Cl)nn12.Cl.NCCCN1CCOCC1>>COCc1cnc2ccc(NCCCN3CCOCC3)nn12.Cl,,CCOCC,,,,test
US20060074119A1,COC(=O)c1sc(-n2cnc3ccccc32)cc1O.Cc1ccccc1CBr>>COC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1ccccc1C,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05075319,CCOC(=O)c1cn(C2CC2)c2c(F)c(N=[N+]=[N-])c(F)cc2c1=O>>CCOC(=O)c1cn(C2CC2)c2c(F)c(N)c(F)cc2c1=O,[Pd],CN(C)C=O,,CCO,,test
US20150166483A1,COc1cc(OCCOCCOCCN2CCOCC2)cc([N+](=O)[O-])c1>>COc1cc(N)cc(OCCOCCOCCN2CCOCC2)c1,[Pd],CCO,,,,test
US20160235734A1,CC(C)(C)OC(=O)N(CCCCCOc1ccc(C(O)(C(=O)O[C@H]2CN3CCC2CC3)c2ccccc2)cc1)C[C@H](O[Si](C)(C)C(C)(C)C)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12>>CC(C)(C)OC(=O)N(CCCCCOc1ccc(C(O)(C(=O)O[C@H]2CN3CCC2CC3)c2ccccc2)cc1)C[C@H](O[Si](C)(C)C(C)(C)C)c1ccc(O)c2[nH]c(=O)ccc12,[Pd],,,O=CO,,test
US20040266815A1,CC(C)(C)n1nc(C2CCC2)cc1N.COC(=O)C(C)(OC)OC>>CC(C)(C)n1nc(C2CCC2)c2ccc(=O)[nH]c21,,CC(=O)O,,,,test
US20160122339A1,CO.Cn1cc(-c2ccc3nnc(Sc4ccc5ncc(-c6cnn(C)c6)c(Cl)c5c4)n3c2)cn1>>COc1c(-c2cnn(C)c2)cnc2ccc(Sc3nnc4ccc(-c5cnn(C)c5)cn34)cc12,,CO,,C[O-].[Na+],,test
US20120202834A1,CC(C)(C)NCCC(=O)OC(C)(C)C.O=Cc1ccc(C(=O)O)cc1>>CC(C)(C)OC(=O)CCN(C(=O)c1ccc(C=O)cc1)C(C)(C)C,,CN(C)C=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20130338137A1,CC1(C)C(=O)Nc2nc(-n3nc(Cc4ccccc4F)c4cc(F)ccc43)nc(O)c21.OCCC(F)(F)F>>CC1(C)C(=O)Nc2nc(-n3nc(Cc4ccccc4F)c4cc(F)ccc43)nc(OCCC(F)(F)F)c21,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090181968A1,CC(C)(C)COC(=O)Cl.O=C(O)COc1ccc(NC(=O)c2ccc(Cn3ccnn3)c3ccccc23)c(C(=O)NCC2CCC2)n1>>CC(C)(C)COC(=O)COc1ccc(NC(=O)c2ccc(Cn3ccnn3)c3ccccc23)c(C(=O)NCC2CCC2)n1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20050176859A1,C1CCNCC1.COC(=O)CCc1ccc(O)c(C(C)(C)C)c1.O=Cc1ccccc1>>COC(=O)CCc1cc(C(c2ccccc2)N2CCCCC2)c(O)c(C(C)(C)C)c1,,Cc1ccccc1,,,,test
US20110086882A1,Cc1nn2ccsc2c1NC(=O)OC(C)(C)C.FC(F)(Br)C(F)(F)Br>>Cc1nn2c(Br)csc2c1NC(=O)OC(C)(C)C,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20100009956A1,N#Cc1ncc(Br)c(N(N)C2CCCC2)n1.O=C(Cl)c1ccc(-c2ccc(CCl)cc2)nc1>>N#Cc1ncc(Br)c(N(NC(=O)c2ccc(-c3ccc(CCl)cc3)nc2)C2CCCC2)n1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US05055598,COC(=O)CC1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1>>Cc1c(C)c2c(c(C)c1O)CCC(C)(CCO)O2,,CCOCC,,[H-].[Na+],,test
US05354502,CCCC1CCC(C(CO)CO)CC1.O=Cc1cc(F)c(Br)c(F)c1>>CCCC1CCC(C2COC(c3cc(F)c(Br)c(F)c3)OC2)CC1,Cc1ccc(S(=O)(=O)O)cc1,ClCCl,,,,test
US20070254869A1,CB1OB(C)OB(C)O1.CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2ccc(Br)cc21>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2ccc(C)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20150018335A1,CC(C)(C)OC(=O)N1CCNCC1.ClC(c1cccnc1)c1cccnc1>>CC(C)(C)OC(=O)N1CCN(C(c2cccnc2)c2cccnc2)CC1,,CC#N,,,,test
US20100144772A1,CC(Oc1ccc(F)cc1F)(C(=O)O)c1ccc(S(C)(=O)=O)cc1.Nc1nccs1>>CC(Oc1ccc(F)cc1F)(C(=O)Nc1nccs1)c1ccc(S(C)(=O)=O)cc1,,ClCCl,,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US20140005213A1,COC[C@@H](C)Oc1ccc2ccc(-c3nnc4ccc([C@@H](N5CC[C@H](NC(=O)OC(C)(C)C)C5)C(F)(F)F)cn34)nc2c1.Cl.ClCCl>>COC[C@@H](C)Oc1ccc2ccc(-c3nnc4ccc([C@@H](N5CC[C@H](N)C5)C(F)(F)F)cn34)nc2c1.Cl.Cl,,ClCCl,,,,test
US20110263556A1,CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)Nc2ccc(OCC(F)F)c(C(=O)O)c2)c1.Nc1ccc(F)c(Cl)c1>>CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)Nc2ccc(OCC(F)F)c(C(=O)Nc3ccc(F)c(Cl)c3)c2)c1,,C1CCOC1,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US06482859B1,CCCCOC(=O)N[C@H](C(=O)NCCc1ccc(OCC#Cc2ccc(Cl)cc2)c(OC)c1)C(C)C>>COc1cc(CCNC(=O)[C@@H](N)C(C)C)ccc1OCC#Cc1ccc(Cl)cc1,,CCOCC,ClCCl,Cl,[Na+].[OH-],test
US20030232872A1,COc1cccc([Mg]Br)c1.O=Cc1ccccc1Br>>COc1cccc(C(O)c2ccccc2Br)c1,,C1CCOC1,,[Cl-].[NH4+],,test
US20090233937A1,CS(=O)(=O)O.Cc1cc(Nc2ncnc3ccn(CCO)c23)ccc1Oc1cccc2sncc12>>Cc1cc(Nc2ncnc3ccn(CCOS(C)(=O)=O)c23)ccc1Oc1cccc2sncc12,,CCO,CCOC(C)=O,,,test
US04503236,COC(=O)c1oc2c3ccccc3n(-c3ccccc3)c2c1OC>>COc1c(C(=O)O)oc2c3ccccc3n(-c3ccccc3)c12,,CO,,O,[Na+].[OH-],test
US04237138,CC(=O)N1CCC(OCCO)CC1.NC(=O)c1ccc(O)cc1>>CC(=O)N1CCC(OCCOc2ccc(C(N)=O)cc2)CC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06140343,CC(=O)Cl.CCOC(=O)N1c2cc3c(cc2[C@H](NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C[C@@H]1C)CCC3>>CCOC(=O)N1c2cc3c(cc2C(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(C)=O)CC1C)CCC3,,ClCCl,,c1ccncc1,,test
US04776929,CC[N+](C)(C)C.COC(=O)[O-]>>CC[N+](C)(C)C.O=C([O-])O,,O,,,,test
US08501722B2,C=CCn1c(S(C)(=O)=O)nc2c(c1=O)C1(CCCCC1)Cc1ccccc1-2.CCN>>C=CCn1c(NCC)nc2c(c1=O)C1(CCCCC1)Cc1ccccc1-2,,CCOCC,CN(C)C=O,C1CCOC1,O=C([O-])[O-].[K+].[K+],test
US20150072980A1,COc1cc2c(cc1N1CCOCC1)C/C(=C\C1CCN(Cc3ccccc3)CC1)C2=O>>COc1cc2c(cc1N1CCOCC1)CC(CC1CCN(Cc3ccccc3)CC1)C2=O,[Pd],CO,,,,test
US05646164,O=C(CBr)c1ccccc1.O=c1ccc2ccc(O)cc2o1>>O=C(COc1ccc2ccc(=O)oc2c1)c1ccccc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20020198196A1,CC1(C)CCCC=C1OS(=O)(=O)C(F)(F)F.CC1(C)OB(c2ccc(C(=O)N3Cc4cccn4Cc4ccccc43)c(Cl)c2)OC1(C)C>>CC1(C)CCCC=C1c1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)c(Cl)c1,,CCOCC,,,,test
US20130143906A1,COC(=O)c1ccc(C)c(-n2c(C)nc(OCc3ccc(F)cc3F)c(Cl)c2=O)c1>>Cc1ccc(C(=O)O)cc1-n1c(C)nc(OCc2ccc(F)cc2F)c(Cl)c1=O,,C1CCOC1,,[Na+].[OH-],,test
US06002008,COc1cc2ncc(C#N)c(Cl)c2cc1OC.NC(=O)c1ccc(N)cc1>>COc1cc2ncc(C#N)c(Nc3ccc(C(N)=O)cc3)c2cc1OC,,CCOCCO,,Cl,c1ccncc1,test
US20110039843A1,O=C(O)c1ccncc1F.O=S(Cl)Cl>>O=C(Cl)c1ccncc1F,,CN(C)C=O,,,,test
US20110251248A1,CCC[C@H](c1ccc(C(=O)NCCC(=O)OCC)cc1)C(c1ccc(Cl)cc1)c1ccc2cc(OC)ccc2c1>>CCC[C@H](c1ccc(C(=O)NCCC(=O)O)cc1)C(c1ccc(Cl)cc1)c1ccc2cc(OC)ccc2c1,,CCO,ClCCl,Cl,[Li+].[OH-],test
US04544621,CC1=C(C)C(=O)N(CCOCCO)C1=O.O=C(O)CCl>>CC1=C(C)C(=O)N(CCOCCOC(=O)CCl)C1=O,,Cc1ccccc1,,O=S(=O)(O)O,,test
US20090186916A1,O=C(O)CCc1cccc(C(F)(F)F)c1>>FC(F)(F)c1ccc2c(c1)CCC2,,O,,O=S(=O)(O)C(F)(F)F,,test
US20150166480A1,CS(=O)(=O)c1ccc(-c2ccc(OCC3CCN(C(=O)C4(C(F)(F)F)CCC4)CC3)cc2)cc1>>CS(=O)(=O)c1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)cc2)cc1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20100234341A1,CCC(=O)Cl.Cc1cc(C)n(-c2nc(N)cc(Cl)n2)n1>>CCC(=O)Nc1cc(Cl)nc(-n2nc(C)cc2C)n1,,CN(C)C=O,,c1ccncc1,O=C([O-])O.[Na+],test
US20100179150A1,CO.Cc1ccc(S(=O)(=O)OC[C@@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2NC(=O)c2[nH]c(C)c(Cl)c2Cl)cc1>>COC[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1NC(=O)c1[nH]c(C)c(Cl)c1Cl,,CO,,C[O-].[Na+],,test
US20080045521A1,C=CCBr.COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1c(Cl)cccc1Cl>>C=CCOc1ccc(C[C@H](NC(=O)c2c(Cl)cccc2Cl)C(=O)OC)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140206680A1,CN(C)C=O.NC(=O)c1cc(F)c(F)nc1Cl>>O=C1NC(O)c2c(F)c(F)nc(Cl)c21,,CC1CCCO1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US06545008B1,Cc1nc(Cl)nc(N2CCc3ccccc3C2C)c1C.Nc1ccc(F)cc1F>>Cc1nc(Nc2ccc(F)cc2F)nc(N2CCc3ccccc3C2C)c1C.Cl,,CCOC(C)=O,CS(C)=O,,,test
US20120295863A1,NCc1ccc(Br)cc1.OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O>>OC[C@H]1O[C@@H](n2cnc3c(NCc4ccc(Br)cc4)ncnc32)[C@H](O)[C@@H]1O,,CCCO,,CCN(C(C)C)C(C)C,Cl,test
US20030220350A1,CC(C)Br.O=C1NC(=O)c2cc1ccc2[N+](=O)[O-]>>CC(C)N1C(=O)c2ccc([N+](=O)[O-])cc2C1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20030207868A1,CC(C)CCn1c(Cn2c(=O)n(C(C)C)c3ccccc32)nc2cc(CO)ccc21.CS(=O)(=O)Cl>>CC(C)CCn1c(Cn2c(=O)n(C(C)C)c3ccccc32)nc2cc(COS(C)(=O)=O)ccc21,,ClCCl,,,,test
US20140088079A1,CCc1ccc(Cc2cc(C3O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)c3c(c2Cl)OCC=C3)cc1>>CCc1ccc(Cc2cc([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c3c(c2Cl)OCCC3)cc1,[Pd],C1CCOC1,CO,,,test
US05977105,OC(CCl)CCc1cccnc1.Oc1ccc(-c2nccs2)cc1>>OC(CCc1cccnc1)COc1ccc(-c2nccs2)cc1,,O,,CCO,[Na+].[OH-],test
US20140128368A1,BrC(Br)(Br)Br.OCc1ccc(Br)cn1>>BrCc1ccc(Br)cn1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110136780A1,CC(C)[C@H](C(=O)N1CC(C#N)C1)N1Cc2c(Cl)cnc3[nH]cc(c23)C1=O.C[Al](C)C>>Cc1cnc2[nH]cc3c2c1CN([C@@H](C(=O)N1CC(C#N)C1)C(C)C)C3=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20100093757A1,Cc1ccccc1-n1nnc2c(O[C@@H](COCCO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)C(=O)Nc3ccc(Cl)cn3)ncnc21>>Cc1ccccc1-n1nnc2c(O[C@@H](COCCO)C(=O)Nc3ccc(Cl)cn3)ncnc21,,CO,,Cl,,test
US20140213580A1,Clc1cc2c(Br)cccc2c(Cl)n1>>Clc1cc2c(Br)cccc2cn1,,CC(=O)O,Cl,[Na+].[OH-],,test
US20140107194A1,CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O.CNC(=O)c1ccc(C[C@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@@H]2O)cc1>>CNC(=O)c1ccc(C[C@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@@H]2OC(=O)[C@@H](N)CC(C)C)cc1,CN(C)c1ccncc1,CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20050267104A1,CC(C)(C)C(=O)O.CCSC(=O)OCI>>CCSC(=O)OCOC(=O)C(C)(C)C,,ClCCl,,O,,test
US20080255122A1,CC(C)(C)N1C(=O)C(O)=C(c2ccccc2)S1(=O)=O.O=C(Cl)C(=O)Cl>>CC(C)(C)N1C(=O)C(Cl)=C(c2ccccc2)S1(=O)=O,,ClCCl,,CN(C)C=O,,test
US20100038578A1,CC[N+]1(COC)CCCC1.N#C[S-]>>CC[N+]1(COC)CCCC1.N#C[S-],,CCO,,[Cl-].[Na+],,test
US20050197386A1,CC(=O)c1ccc(N=C=O)cc1.O=C1OC(CCCCCO)C1Cc1ccccc1>>CC(=O)c1ccc(NC(=O)OCCCCC[C@@H]2OC(=O)[C@H]2Cc2ccccc2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05990102,CC(=O)CC(C)=O.ICCCCCCc1ccccc1>>CC(=O)CCCCCCCc1ccccc1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20150239900A1,C=CC(=O)Cl.CC(C)(C)OC(=O)N1CCN(c2ncnc3c(F)c(Br)c(Cl)cc23)CC1>>C=CC(=O)N1CCN(c2ncnc3c(F)c(Br)c(Cl)cc23)CC1,,O=C(O)C(F)(F)F,,ClCCl,,test
US20110218200A1,CNC.O=[N+]([O-])c1ccc(Br)cc1Nc1ccccc1>>CN(C)c1ccc([N+](=O)[O-])c(Nc2ccccc2)c1,,CN1CCCC1=O,,C1CCOC1,,test
US20160229836A1,CC(C)(C)OC(=O)NCCC[C@@H](NC(=O)CN1CCCNCC1)C(=O)NC1Cc2ccccc2C1>>NCCC[C@@H](NC(=O)CN1CCCNCC1)C(=O)NC1Cc2ccccc2C1,,O=C(O)C(F)(F)F,,,,test
US20030018032A1,Nc1cnccn1.O=Cc1c2ccccc2cc2ccccc12.[C-]#[N+]C(C)(C)C>>CC(C)(C)Nc1c(-c2c3ccccc3cc3ccccc23)nc2cnccn12,,[O-][Cl+3]([O-])([O-])O,,,,test
US20070197478A1,O=C(NCC1CC1)c1cnc(N(Cc2ccccc2)Cc2ccccc2)c2[nH]c(=O)n(Cc3ccccc3)c12>>Nc1ncc(C(=O)NCC2CC2)c2c1[nH]c(=O)n2Cc1ccccc1,,O,O=S(=O)(O)O,O=C([O-])[O-].[K+].[K+],,test
US20080076785A1,COC(=O)C(C(=O)OC)c1nc2ncnn2c(C)c1-c1c(F)cc(F)cc1F>>Cc1nc2ncnn2c(C)c1-c1c(F)cc(F)cc1F,,Cl,,,,test
US20160002273A1,Cc1nc(N2CCC(CCNC(=O)OC(C)(C)C)CC2)c2sc(C(N)=O)cc2n1>>Cc1nc(N2CCC(CCN)CC2)c2sc(C(N)=O)cc2n1,,CO,Cl,,,test
US20150152113A1,Clc1cc(Cl)ncn1.c1ccc(CC2CCNCC2)cc1>>Clc1cc(N2CCC(Cc3ccccc3)CC2)ncn1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05459151,CCOC(=O)C(=O)N1CCC(c2ccc(OC)c(OC3CCCC3)c2)CC1>>COc1ccc(C2CCN(C(=O)C(=O)O)CC2)cc1OC1CCCC1,,C1CCOC1,O,[Li+].[OH-],,test
US20100305336A1,O=C(Cl)CCCl.O=C(c1ccccc1)C(O)(CO)c1ccccc1>>O=C(CCCl)OCC(O)(C(=O)c1ccccc1)c1ccccc1,,CC(C)=O,O,CCOC(C)=O,c1ccncc1,test
US20140018533A1,CCOC(=O)C1=C(Nc2ccc(C(C)C)cc2)OCC1=O.O=Cc1c[nH]c2ncccc12>>CCOC(=O)C1=C(Nc2ccc(C(C)C)cc2)OC(=Cc2c[nH]c3ncccc23)C1=O,,CCO,,C1CCNCC1,,test
US20070238700A1,CC(=O)c1cc(Cl)ccc1NS(=O)(=O)C(F)(F)F.COC(=O)NN>>COC(=O)NN=C(C)c1cc(Cl)ccc1NS(=O)(=O)C(F)(F)F,,CCO,,,,test
US20030055047A1,COC(=O)c1cccnc1C.O=c1n(Cl)c(=O)n(Cl)c(=O)n1Cl>>COC(=O)c1cccnc1CCl,,ClCCl,,,,test
US20090054432A1,COCCOCCl.O=Cc1cccc(Br)c1O>>COCCOCOc1c(Br)cccc1C=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090270350A1,COC(=O)c1ccc(C)c(-n2c(C)cc(OCc3ccc(F)cc3CN)c(Cl)c2=O)c1.Cc1ccc(-n2nc(C(C)(C)C)cc2N)cc1.O=C(Cl)Cl>>COC(=O)c1ccc(C)c(-n2c(C)cc(OCc3ccc(F)cc3CNC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)c(Cl)c2=O)c1,,C1CCOC1,ClCCl,O=C([O-])O.[Na+],,test
US20160024004A1,Nc1cc(F)c(F)c(F)c1.O=C(Cl)c1cc(S(=O)(=O)Cl)ccc1F>>O=C(Nc1cc(F)c(F)c(F)c1)c1cc(S(=O)(=O)Cl)ccc1F,,Cc1ccccc1,,,,test
US20100144739A1,CCOC(=O)CC(=O)OCC.NNc1ccc(Nc2cccc(Cl)c2)nn1>>CCOC(=O)Cc1nnc2ccc(Nc3cccc(Cl)c3)nn12,,CCO,,,,test
US20070249599A1,CI.Cc1nc2ccc(C=C3SC(=S)NC3=O)cc2o1>>CSC1=NC(=O)C(=Cc2ccc3nc(C)oc3c2)S1,,CCO,,CCN(C(C)C)C(C)C,,test
US20150274673A1,COC(=O)C(OC(C)(C)C)c1c(C2=CCC(C)(C)CC2)c(-c2ccccc2)nn1C>>Cn1nc(-c2ccccc2)c(C2=CCC(C)(C)CC2)c1C(OC(C)(C)C)C(=O)O,,CCO,O,[K+].[OH-],,test
US07179827B2,CCOC1=C(O)N=C(CBr)S1=C=O.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOC1=C(S(=O)(=O)c2ccc(C)cc2)N=C(CBr)S1=C=O,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20120184531A1,CC1CC(C(=O)OC(C)(C)C)Nc2oc3c(S(=O)(=O)c4ccccc4)cc(Cl)cc3c21.Cl>>CC1CNCc2c1oc1c(Cl)cc(S(=O)(=O)c3ccccc3)cc21.Cl,,CO,,C1CCOC1,[Na+].[OH-],test
US20100075948A1,CC(C)(CCN=[N+]=[N-])CCO[Si](C)(C)C(C)(C)C>>CC(C)(CCO)CCN=[N+]=[N-],,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06362177B1,CCOc1ccc(C=O)cc1.Nc1ccc(Cl)cc1C(=O)NCC(=O)NCC1CCNCC1>>CCOc1ccc(CN2CCC(CNC(=O)CNC(=O)c3cc(Cl)ccc3N)CC2)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20160009720A1,Cc1ccc(S(=O)(=O)Cl)cc1.N#Cc1ccc(-c2nc(O)c3nccn3c2-c2ccc(N3CCCC3=O)nc2)cc1>>Cc1ccc(S(=O)(=O)Oc2nc(-c3ccc(C#N)cc3)c(-c3ccc(N4CCCC4=O)nc3)n3ccnc23)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20070124152A1,CC(=O)OC(C)=O.CC(C)OCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN)c1=O>>CC(=O)NCCn1c(=O)c(C(=O)NCCOC(C)C)c(O)c2ncc(Cc3ccc(F)cc3)cc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US07678765B2,CC(C)C[C@H](C(=O)OCc1ccccc1)N1CC[C@]2(CCCN2C(=O)C(C)C)C1=O>>CC(C)C[C@H](C(=O)O)N1CC[C@]2(CCCN2C(=O)C(C)C)C1=O,,CO,,,,test
US20130287767A1,CSc1nc(N)c(C#N)s1.Clc1ncnc2[se]c3c(c12)CCCC3>>CSc1nc(Nc2ncnc3[se]c4c(c23)CCCC4)c(C#N)s1,,CN(C)C=O,,[Na+].[OH-],,test
US05219873,BrCc1ccccc1.CC(=NO)c1cccnc1>>CC(=NO)C1=CC=CN(Cc2ccccc2)C1.[Br-],,CCO,,,,test
US20090306008A1,C#C[C@@]1(O)[C@@H](CO)O[C@@H](n2ccc(N)nc2=O)[C@@H]1O.CC(C)(C)[Si](C)(C)Cl>>C#C[C@@]1(O)[C@@H](CO[Si](C)(C)C(C)(C)C)O[C@@H](n2ccc(N)nc2=O)[C@@H]1O,,CN(C)C=O,,c1c[nH]cn1,,test
US20060211712A1,CS(=O)c1csc(-n2c(=O)n(CC(=O)OC(C)(C)C)c3ccccc32)n1>>CS(=O)c1csc(-n2c(=O)n(CC(=O)O)c3ccccc32)n1,,O=C(O)C(F)(F)F,,ClCCl,,test
US20090197871A1,Fc1cc(Br)cc(Br)c1.N#C[Cu]>>N#Cc1cc(F)cc(Br)c1,,c1ccncc1,,CN(C)C=O,,test
US20080103123A1,CN(Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1)C1CCN(C(=O)OC(C)(C)C)CC1>>CN(Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1)C1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04547506,ClCc1ccccc1Cl.NCCCNc1ccccn1>>NCCCN(Cc1ccccc1Cl)c1ccccn1,,CS(C)=O,,O,[H-].[Na+],test
US04174397,BrBr.CC1CCC(=O)c2ccccc21>>CC1CC(Br)C(=O)c2ccccc21,,CCOC(C)=O,,,,test
US05114940,CCOC=CC(=O)Cl.Nc1ccccc1F>>CCOC=CC(=O)Nc1ccccc1F,,c1ccncc1,,,,test
US20160045505A1,CC(C)(C)OC(=O)Nc1cnc2nc(-c3cc(NC(=O)N4CCCC4)ccc3F)cn2c1.O=C(O)C(F)(F)F>>O=C(Nc1ccc(F)c(-c2cn3cc(NC(=O)C(F)(F)F)cnc3n2)c1)N1CCCC1,,ClCCl,,,,test
US05166399,CON=C(C(=O)OC)c1ccccc1COc1ccc(C(C)=O)cc1.NOCc1ccccc1>>CON=C(C(=O)OC)c1ccccc1COc1ccc(C(C)=NOCc2ccccc2)cc1,,CO,,Cl,,test
US20110053952A1,CC(C)(C)OC(=O)N1CCCCC1C(=O)O.COc1ccc(-c2cnc(Nc3cnc(C)c(N)c3)nc2)cc1>>COc1ccc(-c2cnc(Nc3cnc(C)c(NC(=O)C4CCCCN4C(=O)OC(C)(C)C)c3)nc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06313311B1,O=Cc1cc2c(cc1O)C(Cc1c[nH]cn1)CC2>>OCc1cc2c(cc1O)C(Cc1c[nH]cn1)CC2,,CCO,,O,[BH4-].[Na+],test
US20080207611A1,CC(C)(C)OC(=O)N1CCC(O)CC1.COCCBr>>COCCOC1CCN(C(=O)OC(C)(C)C)CC1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20160038504A1,Cc1ccc(N)cc1-c1cc(N2CCOCC2)c(OCCO)nn1.O=C(O)c1ccnc(C(F)(F)F)c1>>Cc1ccc(NC(=O)c2ccnc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c(OCCO)nn1,,CN(C)C=O,,ClCCCl,On1nnc2cccnc21,test
US20050014755A1,Nc1nnc(Cc2ccc(F)cc2)n1N.O=C1Nc2ccc(O)c(Cl)c2C1=O>>Oc1ccc2[nH]c3nc4nnc(Cc5ccc(F)cc5)n4nc3c2c1Cl,,OCCO,,,,test
US20160221945A1,CC(C)(C)OC(=O)N1CC[C@@H](O)[C@H]1C(=O)NCc1cc(-c2ccc(C(F)(F)F)nc2)ncn1.CCN(CC)S(F)(F)F>>CC(C)(C)OC(=O)N1CC[C@H](F)[C@H]1C(=O)NCc1cc(-c2ccc(C(F)(F)F)nc2)ncn1,,ClCCl,,,,test
US20020082278A1,C(=C\c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)\CCOCc1ccccc1>>OCCCCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1,[Pd],CCO,,Cl,,test
US05593984,C=O.Cc1nccn2cccc12>>Cc1nccn2c(CO)ccc12,,Cl,O,[Na+].[OH-],,test
US20120252805A1,Cc1cc(NS(=O)(=O)c2cccc(Cl)c2)c2c(Br)c(-c3cnn(C(=O)OC(C)(C)C)c3)sc2n1.OB(O)c1cccc(N2CCOCC2)c1>>Cc1cc(NS(=O)(=O)c2cccc(Cl)c2)c2c(-c3cccc(N4CCOCC4)c3)c(-c3cn[nH]c3)sc2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20090124641A1,CC(C)(C)[Si](OCC(F)C=O)(c1ccccc1)c1ccccc1.CC(C)C(N)c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1>>CC(C)C(NCC(F)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US06239131B1,CCOC(=O)c1cccc(N)c1.Cc1ccc2c(c1)N(CC(=O)C(C)(C)C)C(=O)C(N)CN2C1CCCCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCOC(=O)c1cccc(NC(=O)NC2CN(C3CCCCC3)c3ccc(C)cc3N(CC(=O)C(C)(C)C)C2=O)c1,,C1CCOC1,,CCN(CC)CC,,test
US20100233116A1,CCOC(=O)c1sc(NC(=O)NCCCl)cc1C>>CCOC(=O)c1sc(N2CCNC2=O)cc1C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20050130973A1,C[Si](C)(C)c1cc2ccccc2o1.O=C(Cl)Cc1ccc(Br)cc1>>O=C(Cc1ccc(Br)cc1)c1cc2ccccc2o1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20140163226A1,COC(=O)CCc1ccc(-c2csc3c(N)ncnc23)cc1.O=C=Nc1cccc(Cl)c1>>CC(C(=O)O)c1ccc(-c2csc3c(NC(=O)Nc4cccc(Cl)c4)ncnc23)cc1,,C1CCOC1,O,CO,[Na+].[OH-],test
US20060270675A1,CCOC(=O)N1c2ccc(C(F)(F)F)cc2[C@@H](NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C[C@H]1CC.N#CBr>>CCOC(=O)N1c2ccc(C(F)(F)F)cc2[C@@H](N(C#N)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C[C@H]1CC,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20090029981A1,COCCCN1C(=O)COc2ccc(CO[C@H]3CN(C(=O)OCc4ccccc4)C[C@@H](COC(c4ccccc4)(c4ccccc4)c4ccccc4)[C@@H]3c3ccc(OC)cc3)cc21>>COCCCN1C(=O)COc2ccc(CO[C@H]3CN(C(=O)OCc4ccccc4)C[C@@H](CO)[C@@H]3c3ccc(OC)cc3)cc21,,C1CCOC1,CO,O=C([O-])O.[Na+],,test
US05177077,Fc1ccc(C(Cl)c2cccs2)cc1.OCCN1CCN(CC=Cc2ccco2)CC1>>Fc1ccc(C(OCCN2CCN(CC=Cc3ccco3)CC2)c2cccs2)cc1,,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US03931177,CC(C)N.O=C1CCC(c2ccc(OCC3CO3)cc2)=NN1>>CC(C)NCC(O)COc1ccc(C2=NNC(=O)CC2)cc1,,CO,,,,test
US20130116246A1,CN1Cc2cc([N+](=O)[O-])nn2CC1=O>>CN1Cc2cc(N)nn2CC1=O,[Pd],CCO,,[H][H],,test
US20130090298A1,Cc1ccc(S(=O)(=O)OC[C@H]2O[C@@H](c3ccc(Cl)c(Cc4ncc(-c5ccco5)s4)c3)[C@H](O)[C@@H](O)[C@@H]2O)cc1.[I-]>>O[C@H]1[C@H](c2ccc(Cl)c(Cc3ncc(-c4ccco4)s3)c2)O[C@H](CI)[C@@H](O)[C@@H]1O,,CCC(C)=O,,O,,test
US20110263592A1,COC(CBr)OC.Nc1ncccc1C(=O)O>>O=C(O)c1cccn2ccnc12,,CC#N,,,,test
US20100179149A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=c1ccc(-c2ccc(O)cc2)n[nH]1>>CC(C)(C)OC(=O)Oc1ccc(-c2ccc(=O)n(C(=O)OC(C)(C)C)n2)cc1,,C1COCCO1,CC#N,O=C([O-])[O-].[Cs+].[Cs+],,test
US05312929,CC(=O)CCl.CCOC(=O)C(C)(C)N>>CCOC(=O)C(C)(C)NCC(C)=O,,CC(=O)N(C)C,,CCN(CC)CC,Cl,test
US20120295885A1,Cc1ccc(S(=O)(=O)n2cc(C#N)c3cncnc32)cc1>>N#Cc1c[nH]c2ncncc12,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05591891,CC(O)=S.CCC(c1ccccc1)[C@@H](Br)C(=O)O>>CCC(c1ccccc1)[C@H](SC(C)=O)C(=O)O,,CN(C)C=O,,[H-].[Na+],,test
US04088642,CC(C)(C)N=NC(C)(Cl)CC(C)(C)OOC(C)(C)C.CC(C)(C)c1ccc(S)cc1>>CC(C)(C)N=NC(C)(CC(C)(C)OOC(C)(C)C)Sc1ccc(C(C)(C)C)cc1,,O,,CO,[K+].[OH-],test
US20130225552A1,Cl.Cn1c(=O)n([C@@H]2C[C@@H](NC(=O)OC(C)(C)C)C2)c2ncc(F)cc21>>Cl.Cn1c(=O)n([C@H]2C[C@H](N)C2)c2ncc(F)cc21,,C1COCCO1,,,,test
US20050234101A1,O=S(Cl)Cl.OCc1cc(Br)ccc1OCCN1CCCC1>>ClCc1cc(Br)ccc1OCCN1CCCC1,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20090082440A1,CC(C)(COS(=O)(=O)CCCCl)[C@@H](OCc1ccccc1)C(=O)O.CN(C)C(=O)CO>>CN(C)C(=O)COC(=O)[C@H](OCc1ccccc1)C(C)(C)COS(=O)(=O)CCCCl,,ClCCl,,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20150361100A1,CO.O=C(O)c1cc2cccnn2c1>>COC(=O)c1cc2cccnn2c1,O=S(=O)(O)O,,,,,test
US20040142961A1,CC(C)(C)C(=O)CBr.Cc1ccnc(N)c1>>Cc1ccn2cc(C(C)(C)C)nc2c1,,CCO,,,,test
US20080182854A1,COC(=O)Nc1ccc(C=O)cc1.N#CCC#N>>COC(=O)Nc1ccc(C=C(C#N)C#N)cc1,C1CCNCC1,CCO,,,,test
US20160052884A1,Cn1c(=O)c2ccc([N+](=O)[O-])cc2n1C(=O)OC(C)(C)C>>Cn1c(=O)c2ccc(N)cc2n1C(=O)OC(C)(C)C,[Pd],CCO,,,,test
US20160176857A1,C[C@H]1CC(c2ccc(Nc3n[nH]c(N)c3C(N)=O)cn2)C[C@@H](C)O1.Cc1cc(C=O)cc(C)c1O>>Cc1cc(CNc2[nH]nc(Nc3ccc(C4C[C@H](C)O[C@H](C)C4)nc3)c2C(N)=O)cc(C)c1O,,CC(=O)O,CCO,O,[BH4-].[Na+],test
US20130150339A1,CC(C)(C)OC(=O)NNC1CN(C(c2ccccc2)c2ccccc2)C1.Cl>>Cl.NNC1CN(C(c2ccccc2)c2ccccc2)C1,,C1COCCO1,,,,test
US20130079342A1,COC(=O)c1cc(N2CCOCC2)cc(Cl)n1>>O=C(O)c1cc(N2CCOCC2)cc(Cl)n1,,CO,,C1CCOC1,[Li+].[OH-],test
US05539112,CC(=O)O.CC(C)(C)C(=O)Nc1ccc(-c2cc(=O)c3c(NC(=O)C(C)(C)C)c(F)c(CO)c(F)c3o2)cc1F>>CC(=O)OCc1c(F)c(N)c2c(=O)cc(-c3ccc(N)c(F)c3)oc2c1F,,O=S(=O)(O)O,,,,test
US05093356,CSc1ccc(/C=C2/C(C)=C(CC=O)c3cc(F)ccc32)cc1.NO>>CSc1ccc(/C=C2/C(C)=C(CC=NO)c3cc(F)ccc32)cc1,,CCO,,CCN(CC)CC,Cl,test
US20090036448A1,Cc1nc(N[C@@H]2CC[C@H](CNC(=O)OCc3ccccc3)CC2)cc(N(C)C)n1>>Cc1nc(N[C@@H]2CC[C@H](CN)CC2)cc(N(C)C)n1,[Pd],CCO,,,,test
US20120329818A1,CC(C)(C)OC(=O)N1CCC(C)(C(=O)O)CC1.Nc1cccc(S(N)(=O)=O)c1>>CC(C)(C)OC(=O)N1CCC(C)(C(=O)Nc2cccc(S(N)(=O)=O)c2)CC1,CN(C)C=O,CC(Cl)Cl,ClCCl,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20020151501A1,CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)O.CC(C)C[N-]CC(C)C>>CC(C)C[N-]CC(C)C.O=C(O)[C@H]1CCCN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070043080A1,CC(C)C(=O)Nc1cccc(C2CCN(CCCCCCN)CC2)c1.O=C=Nc1ccc(Cl)cc1Cl>>CC(C)C(=O)Nc1cccc(C2CCN(CCCCCCNC(=O)Nc3ccc(Cl)cc3Cl)CC2)c1,,C1CCOC1,,,,test
US20080312272A1,CC(C#N)(Cn1nc2cc(Cl)cc(CNC(=O)OC(C)(C)C)c2n1)NC(=O)c1ccc(OC(F)(F)F)cc1>>CC(C#N)(Cn1nc2cc(Cl)cc(CN)c2n1)NC(=O)c1ccc(OC(F)(F)F)cc1,,ClCCl,,C[Si](C)(C)I,,test
US20070161627A1,COc1ccc2nccc(CCN3CCC(N(C)N)C3)c2n1.O=C1CSc2ccc(C(=O)O)nc2N1>>COc1ccc2nccc(CCN3CCC(N(C)NC(=O)c4ccc5c(n4)NC(=O)CS5)C3)c2n1,,CN(C)C=O,ClCCl,ClCCCl,On1nnc2ccccc21,test
US20030211978A1,Cc1ccc(O)cc1.O=C(Cl)CCCl>>Cc1ccc(OC(=O)CCCl)cc1,,ClCCl,,c1ccncc1,,test
US04760146,N.O=C(Cl)C1(CCCCl)CC=CCC1c1ccccc1>>NC(=O)C1(CCCCl)CC=CCC1c1ccccc1,,ClCCl,,,,test
US20110105462A1,CCN.Cc1ccc(S(=O)(=O)OCC2COc3ccc(OS(=O)(=O)C(F)(F)F)cc3O2)cc1>>CCNCC1COc2ccc(OS(=O)(=O)C(F)(F)F)cc2O1,,CC#N,,,,test
US06265434B1,CC(C)(C)OC(=O)N1CCC(C=O)CC1>>CC(C)(C)OC(=O)N1CCC(CO)CC1,,C1CCOC1,,[BH4-].[Na+],,test
US04547519,Nc1ccncc1.O=C(O)CCC12CCC(=O)N1C(=O)CC2>>O=C(CCC12CCC(=O)N1C(=O)CC2)Nc1ccncc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20100160424A1,CN(C(=O)OC(C)(C)C)C(CN)C[C@H]1CCCOC1.O=C(Cl)OCc1ccccc1>>CN(C(=O)OC(C)(C)C)C(CNC(=O)OCc1ccccc1)C[C@H]1CCCOC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160264518A1,COC(=O)CCc1ccc2nc(CNc3ccccc3/C=C/C(=O)OC(C)(C)C)[nH]c2c1.N>>CC(C)(C)OC(=O)/C=C/c1ccccc1NCc1nc2ccc(CCC(N)=O)cc2[nH]1,,CO,,,,test
US20120065204A1,COC(=O)c1ccc2c(c1)C=C(C(=O)O)CO2>>COC(=O)c1ccc2c(c1)CC(C(=O)O)CO2,,CO,,,,test
US20080194552A1,Nc1cncc(C#Cc2cnc(N)nc2)c1.O=C(O)c1cccc(N2CCOCC2)c1>>Nc1ncc(C#Cc2cncc(NC(=O)c3cccc(N4CCOCC4)c3)c2)cn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120252780A1,BrCCBr.Nc1nc(Cl)cnc1O>>Clc1cnc2c(n1)NCCO2,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140057895A1,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.CCc1nn(C(N)=NO)c2cc(F)ccc12>>CCc1nn(-c2noc(C3CCN(C(=O)OC(C)(C)C)CC3)n2)c2cc(F)ccc12,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150322043A1,CC(NS(=O)C(C)(C)C)c1c[nH]nn1.Cl>>CC(N)c1c[nH]nn1.Cl,,CO,,,,test
US20130045522A1,CC(C)(C)OC(=O)CCOCCOCCO.CCOC(C)=O.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)CCOCCOCCO.CS(=O)(=O)O,,CCCCCC,ClCCl,CCN(CC)CC,,test
US20090029981A1,C=CC(=O)OC.COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)C[C@@H](O)[C@@H]3c3ccc(OC)cc3)cc21>>COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)C[C@@H](OCCC(=O)OC)[C@@H]3c3ccc(OC)cc3)cc21,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20080312226A1,Cc1cc(N)n(C)n1.O=C(Cl)OCC(Cl)(Cl)Cl>>Cc1cc(NC(=O)OCC(Cl)(Cl)Cl)n(C)n1,,CC(=O)N(C)C,,O,,test
US20130035318A1,C=C(C)[C@@H]1CC[C@]2(NCC)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NCC)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1COCCO1,CO,[Na+].[OH-],,test
US20040023989A1,CCOC(=O)c1cc(C2CCCC2)[nH]n1>>O=C(O)c1cc(C2CCCC2)[nH]n1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20130029949A1,COc1cc(-c2cc(O)c3cccnc3c2)ccc1OC(C)C.C[C@H](c1ccccc1)N1C[C@H](CO)OC1=O>>COc1cc(-c2cc(OC[C@H]3CNC(=O)O3)c3cccnc3c2)ccc1O,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100048666A1,CC(C(=O)O)c1ccc(CC2CSCC2O)cc1.Cc1ccc(S(=O)(=O)O)cc1>>Cc1ccc(S(=O)(=O)OC2CSCC2Cc2ccc(C(C)C(=O)O)cc2)cc1,,Cc1ccccc1,,,,test
US20100292260A1,COc1ccc(CCl)cc1.OCCBr>>COc1ccc(COCCBr)cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20030181499A1,CC(=O)c1cn(S(=O)(=O)c2ccccc2)c2ccc(Cl)cc12.COc1ccccc1C(=O)Cl>>COc1ccccc1C(=O)CC(=O)c1cn(S(=O)(=O)c2ccccc2)c2ccc(Cl)cc12,,C1CCOC1,O,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20070293507A1,Nc1ccccc1NC(=O)c1cc(/C=C/c2ccc(O)cc2)n[nH]1>>Oc1ccc(/C=C/c2cc(-c3nc4ccccc4[nH]3)n[nH]2)cc1,,CC(=O)O,,,,test
US20120270868A1,C=O.N#Cc1ccc(-c2cnn(Cc3cccc(C(=O)Nc4nc5c(s4)C[C@@H](NCCC(F)(F)F)CC5)c3)c2)cc1>>CN(CCC(F)(F)F)[C@H]1CCc2nc(NC(=O)c3cccc(Cn4cc(-c5ccc(C#N)cc5)cn4)c3)sc2C1,,CO,ClCCl,[BH3-]C#N.[Na+],,test
US20120114739A1,CC(C)(C)OC(=O)N1CCN(c2nc3c(-c4cnc5ccccc5c4)cnn3c(N)c2Br)CC1.Cl>>Nc1c(Cl)c(N2CCNCC2)nc2c(-c3cnc4ccccc4c3)cnn12,,C1COCCO1,,,,test
US20060106037A1,CC(O)CN.CCOC(OCC)(OCC)c1ccccc1.N#CC(N)C(N)=O>>CC(O)Cn1c(-c2ccccc2)nc(C(N)=O)c1N,,CC#N,,,,test
US20100317643A1,[N-]=[N+]=Nc1cc(NC(=O)c2c(Cl)cc(Cl)cc2Cl)ccn1>>Nc1cc(NC(=O)c2c(Cl)cc(Cl)cc2Cl)ccn1,,CCO,,,,test
US20110212939A1,CC(C)(C)OC(=O)N1CCC(CCCO)CC1.Cc1nnnn1-c1ccc(O)cc1F>>Cc1nnnn1-c1ccc(OCCCC2CCN(C(=O)OC(C)(C)C)CC2)cc1F,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150191478A1,O=Cc1cc2cncc(C3=CCNCC3)c2o1.O=S(=O)(Cl)C1CC1>>O=Cc1cc2cncc(C3=CCN(S(=O)(=O)C4CC4)CC3)c2o1,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20120225888A1,COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc(-c3cccc(Cl)c3)nn2c1Cl.Cc1c(B2OC(C)(C)C(C)(C)O2)cc(F)c2c1CCCO2>>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc(-c3cccc(Cl)c3)nn2c1-c1cc(F)c2c(c1C)CCCO2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04079066,CCOC(=O)CC(=O)c1ccc2ccccc2c1.Oc1cccc(O)c1>>O=c1cc(-c2ccc3ccccc3c2)c2ccc(O)cc2o1,,O=S(=O)(O)O,,O,,test
US20080064678A1,C1CCNCC1.CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)cc2ccc(-c3cccc(CCl)c3)cc2c1=O>>CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)cc2ccc(-c3cccc(CN4CCCCC4)c3)cc2c1=O,,ClCCl,,,,test
US20040266789A1,COC(=O)c1ccc(-c2ccc(Br)cc2)cc1>>OCc1ccc(-c2ccc(Br)cc2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130096056A1,NCc1ccccc1.Nc1nc(Cc2ccccc2)c(C(=O)O)s1>>Nc1nc(Cc2ccccc2)c(C(=O)NCc2ccccc2)s1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,On1nnc2ccccc21,test
US20050096336A1,CCOC(=O)COc1ccc(N(C)C(CC)c2ccc(-c3cccc(C(F)(F)F)c3)nc2C)c2ccccc12>>CCC(c1ccc(-c2cccc(C(F)(F)F)c2)nc1C)N(C)c1ccc(OCC(=O)O)c2ccccc12,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20110009636A1,CC1(C)COC(C(C)(C)c2ccc(CCCl)cc2)=N1.CCOCCn1c(C2CCNCC2)nc2ccccc21>>CCOCCn1c(C2CCN(CCc3ccc(C(C)(C)C4=NC(C)(C)CO4)cc3)CC2)nc2ccccc21,,CO,,O=C([O-])[O-].[Na+].[Na+],,test
US20060155132A1,CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21>>CCNC1CC(C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21,,O,,,,test
US04698349,CC1(C)OC(=O)CC(=O)O1.O=C(O)Cc1ccccn1>>O=C(O)c1c(O)cc2ccccn2c1=O,,CN(C)C=O,,Cl,,test
US04861799,CC(=O)Cl.Nc1ccc(-c2ccc(Br)cc2)cc1>>CC(=O)Nc1ccc(-c2ccc(Br)cc2)cc1,,c1ccncc1,,,,test
US04870078,CC(=O)c1ccc(N2CCNCC2)cc1.O=S1(=O)CCCO1>>CC(=O)c1ccc(N2CCN(CCCS(=O)(=O)O)CC2)cc1,,CC(C)=O,,,,test
US20140194431A1,CC(C)(C)OC(=O)c1nc(CC2(c3ccccc3)CCCC2)nc(O)c1OCc1ccccc1>>O=C(O)c1nc(CC2(c3ccccc3)CCCC2)nc(O)c1OCc1ccccc1,,C1CCOC1,O,,,test
US20030229094A1,O=C(CCl)Nc1ccccc1C(F)(F)F.c1ccc(N2CCNCC2)nc1>>O=C(CN1CCN(c2ccccn2)CC1)Nc1ccccc1C(F)(F)F,,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090324581A1,COC(=O)c1ccc(C(F)(F)F)c(C2CCCC2)c1>>OCc1ccc(C(F)(F)F)c(C2CCCC2)c1,,C1CCOC1,,Cl,[BH4-].[Li+],test
US20100249229A1,C=CCC1=C[C@H]2[C@@H](C1)C[C@]2(CC(=O)OC(C)(C)C)C[N+](=O)[O-]>>C=CCC1=C[C@H]2[C@@H](C1)C[C@@]2(CN)CC(=O)O,[Fe],CCO,O,[Cl-].[NH4+],,test
US04900749,CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCN.COC(OC)N(C)C>>CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCNC=O,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US05190958,BrCc1ccccc1.O=C1CCCCN1>>O=C1NCCCC1Cc1ccccc1,,C1CCOC1,O,[Li]CCCC,[Cl-].[NH4+],test
US20040259845A1,C1CCOC1.CCCCCCCCCCBr.CCOCC.O.c1ccc(C(OC(c2ccccc2)(c2ccccc2)c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCCCCCCCCCCOCC(COC(c1ccccc1)(c1ccccc1)c1ccccc1)OCCCCCCCCCC,,C1CCOC1,,[H-].[Na+],,test
US20030096812A1,CC1CNCC(C)(C)C1=O.[NH4+]>>CC1CNCC(C)(C)C1N,,CO,,[BH3-]C#N.[Na+],,test
US06018046,CC(C)OC(=O)CBr.O=c1ccn2c3ccc(Br)cc3c3cc(O)cc1c32>>CC(C)OC(=O)COc1cc2c(=O)ccn3c4ccc(Br)cc4c(c1)c23,,CS(C)=O,,[I-].[K+],,test
US20070265225A1,CCC1(CC)NC[C@@H](c2cc(F)cc(F)c2)N(CC(=O)OC)C1=O.Cl>>CCC1(CC)NC[C@@H](c2cc(F)cc(F)c2)N(CC(=O)O)C1=O.Cl,,C1CCOC1,O,[Li+].[OH-],,test
US20100197717A1,Cc1nn(C)c(C)c1-c1cccc2c1CC[C@H](N)C2.Cl>>Cc1nn(C)c(C)c1-c1cccc2c1CC[C@H](N)C2.Cl,,CCOCC,,,,test
US20140148611A1,Cc1cc(Br)cc(C(=O)OCc2ccccc2)c1N.N#C[Cu]C#N>>Cc1cc(C#N)cc(C(=O)OCc2ccccc2)c1N,,CN1CCCC1=O,,,,test
US20150225401A1,COCC1(C(=O)N(C)OC)CCN(C(=O)OC(C)(C)C)CC1.C[Mg]Br>>COCC1(C(C)=O)CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,,,test
US20070293516A1,CC(C)n1nc(I)c2c(N)ncnc21.OB(O)c1ccc(O)cc1>>CC(C)n1nc(-c2ccc(O)cc2)c2c(N)ncnc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US20060058309A1,BrP(Br)Br.Cc1ccc2c(n1)C(O)CCC2>>Cc1ccc2c(n1)C(Br)CCC2,,Cc1ccccc1,,[Na+].[OH-],,test
US04034090,CC(C)(C)C(=O)OCI.Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(NC(=O)Cc3csc(=O)s3)C2SC1>>Cn1nnnc1SCC1=C(C(=O)OCOC(=O)C(C)(C)C)N2C(=O)C(NC(=O)Cc3csc(=O)s3)C2SC1,,CN(C)C=O,,[Na],,test
US20080318991A1,CC(C)=CCBr.CCOC(=O)C1CCCN(C(=O)OCc2ccccc2)C1>>CCOC(=O)C1(CC=C(C)C)CCCN(C(=O)OCc2ccccc2)C1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US06166049,CN(CCOc1ccc(CC(OCC(F)(F)F)C(=O)O)cc1)c1nc2ccccc2o1.O=C(Cl)C(=O)Cl>>CN(CCOc1ccc(CC(OCC(F)(F)F)C(=O)Cl)cc1)c1nc2ccccc2o1,,c1ccccc1,,,,test
US20130109662A1,C=C1CC(=O)O1.CC1CNCC(C)O1>>CC(=O)CC(=O)N1CC(C)OC(C)C1,,C1CCOC1,,,,test
US20150291563A1,NC1CCN(c2ccc(C3CC(C(O)(C(F)(F)F)C(F)(F)F)=NN3c3ccccc3Cl)cc2)CC1.O=S(=O)(Cl)C1CC1>>O=S(=O)(NC1CCN(c2ccc(C3CC(C(O)(C(F)(F)F)C(F)(F)F)=NN3c3ccccc3Cl)cc2)CC1)C1CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20160137636A1,COc1cc(-c2cccc(F)c2)ccc1C1c2ccc(S(=O)(=O)Cl)cc2CCN1C(C)=O.COc1ccc(CNc2nncs2)cc1>>COc1ccc(CN(c2nncs2)S(=O)(=O)c2ccc3c(c2)CCN(C(C)=O)C3c2ccc(-c3cccc(F)c3)cc2OC)cc1,,CCO,CCOC(C)=O,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20050043392A1,CC#C[C@H](O)[C@@H](N)CNC(=O)OCc1ccccc1.CC(C)(C)OC(=O)Nc1cc(NC(=O)CC(=O)O)cc(C(F)(F)F)c1>>CC#C[C@H](O)[C@H](CNC(=O)OCc1ccccc1)NC(=O)CC(=O)Nc1cc(NC(=O)OC(C)(C)C)cc(C(F)(F)F)c1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04361575,C=CCN(C1=NCCN1)c1c(Cl)cccc1Cl.CI>>C=CCN(C1=NCCN1C)c1c(Cl)cccc1Cl,,C1CCOC1,,[H-].[Na+],,test
US20060194801A1,COC(=O)c1cc(F)c(C#CC(C)(C)C)cc1Cl>>CC(C)(C)C#Cc1cc(Cl)c(C(=O)O)cc1F,,CO,,[Na+].[OH-],,test
US20110118273A1,CC(C)Oc1ccc(Cl)nn1.CCC(CC)C(=O)c1c[nH]c2cnc(-c3c(C)cccc3C)cc12>>CCC(CC)C(=O)c1cn(-c2ccc(OC(C)C)nn2)c2cnc(-c3c(C)cccc3C)cc12,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04246021,CO.COC(OC)OC.O=Cc1ccc(Cl)c(Cl)c1>>COC(OC)c1ccc(Cl)c(Cl)c1,,CO,,Cl,C[O-].[Na+],test
US20090215818A1,C=Cc1ccc2ncc(C(=N)NO)n2c1.CC(=O)OC(C)=O>>C=Cc1ccc2ncc(-c3noc(C)n3)n2c1,,Cc1ccccc1,,,,test
US05700819,COC(=O)Cc1cccc(CC(=O)Cl)c1.Nc1c(F)c(F)cc(F)c1S>>COC(=O)Cc1cccc(Cc2nc3c(F)c(F)cc(F)c3s2)c1,,CN1CCCC1=O,O,,,test
US20060199851A1,C=[N+]=[N-].CCN(CC(Cc1ccc(OCc2ccccc2)cc1)NC(=O)OC(C)(C)C)C[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C>>CCN(CC(Cc1ccc(OC)cc1)NC(=O)OC(C)(C)C)C[C@H](Cc1ccc(OC)cc1)NC(=O)OC(C)(C)C,,CCOCC,,,,test
US20150119373A1,CC1(C)CC(=O)OC1=O.CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2CC[C@@H]2[C@H]3[C@H](C4(C)CC4)CC[C@]3(C(=O)N3CCC(C(=O)NCCN4CCOCC4)CC3)CC[C@]21C>>CC(C)(CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC[C@@H]2[C@H]4[C@H](C5(C)CC5)CC[C@]4(C(=O)N4CCC(C(=O)NCCN5CCOCC5)CC4)CC[C@]23C)C1(C)C)C(=O)O,,ClCCl,,Cc1ccccc1,,test
US20040102467A1,CCCCCCCCBr.c1ccc(COc2ccc3[nH]ccc3c2)cc1>>CCCCCCCCn1ccc2cc(OCc3ccccc3)ccc21,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US05981492,N[C@@H](CO)c1ccccc1.O=C(OCc1ccccc1)ON1C(=O)CCC1=O>>O=C(N[C@@H](CO)c1ccccc1)OCc1ccccc1,,CN(C)C=O,,,,test
US05055598,Cc1c(C)c2c(c(C)c1O)CCC(C)(CCN)O2.Cl.N=C(N)Nc1ccc(C(=O)O)cc1>>Cc1c(C)c2c(c(C)c1O)CCC(C)(CCNC(=O)c1ccc(NC(=N)N)cc1)O2.Cl,,CN(C)C=O,c1ccncc1,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20040102459A1,C=CC(=O)OC.Nc1nc2ncnc-2c(-c2ccco2)[nH]1>>COC(=O)CCn1cnc2c(-c3ccco3)nc(N)nc21,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US06475595B1,CCCCCC1CCC(c2ccc(OCC)c(F)c2F)CC1O>>CCCCCC1CCC(c2ccc(OCC)c(F)c2F)CC1=O,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20160221953A1,CNC1CCN(C)CC1.N#Cc1ccc(C(=O)O)cc1>>CN1CCC(N(C)C(=O)c2ccc(C#N)cc2)CC1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US05378726,BrCCBr.Cc1cccc(O)c1O>>Cc1cccc2c1OCCO2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100105607A1,BrCCCOc1ccccc1.CCO>>CCOCCCOc1ccccc1,,CCO,,C,C[O-].[Na+],test
US20140171403A1,CC(C)(C)OC(=O)NCCC1CCN(C(=O)/C=C/c2cc(Cl)cc(Cl)c2)CC1>>NCCC1CCN(C(=O)/C=C/c2cc(Cl)cc(Cl)c2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160229843A1,COc1cncc(-c2ccc3nc(C)ccc3c2)c1.O=[Se]=O>>COc1cncc(-c2ccc3nc(C=O)ccc3c2)c1,,C1COCCO1,ClCCl,,,test
US20080280875A1,CCOC(=O)c1cc(Oc2ccc(S(C)(=O)=O)cc2)c2cc(CBr)oc2c1.O=C1CCCN1>>CCOC(=O)c1cc(Oc2ccc(S(C)(=O)=O)cc2)c2cc(CN3CCCC3=O)oc2c1,,CN(C)C=O,,O,[H-].[Na+],test
US06414005B1,CC(C)(C)OC(=O)N(Cc1cc(NC(N)=S)ccc1-n1cccc1)C(=O)OC(C)(C)C.CCI>>CCSC(=N)Nc1ccc(-n2cccc2)c(CN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1,,CC(C)=O,,,,test
US03965179,C#C.O=C(c1ccccc1)c1ccc([N+](=O)[O-])cc1>>C#CC(O)(c1ccccc1)c1ccc([N+](=O)[O-])cc1,,C1CCOC1,,Cl,,test
US05807883,CCCCCN1C(=O)C(CCC(=O)OC)(NC(=O)c2ccc(Cl)c(Cl)c2)c2ccccc21>>CCCCCN1C(=O)C(CCC(=O)O)(NC(=O)c2ccc(Cl)c(Cl)c2)c2ccccc21,,CO,,[Na+].[OH-],,test
US20130245254A1,CC(C)N.CCOC(=O)CNc1ncc(Br)nc1Br>>CCOC(=O)CNc1ncc(Br)nc1NC(C)C,,O,,CCN(C(C)C)C(C)C,CS(C)=O,test
US04436742,CC(C)N.c1cc(OCC2CO2)c2nsnc2c1>>CC(C)NCC(O)COc1cccc2nsnc12,,C1COCCO1,,,,test
US20020183364A1,O=C1Cc2cc(Br)ccc2N1.O=Cc1cc2ccccc2[nH]1>>O=C1Nc2ccc(Br)cc2C1=Cc1cc2ccccc2[nH]1,,CCO,,C1CCNCC1,,test
US20120232083A1,CCOC(=O)[C@@](C)(CCn1cc(F)c(-c2ccc(OC[C@@H]3CC[C@@H](OC4CCCCO4)CC3)cc2)cc1=O)S(C)(=O)=O>>C[C@@](CCn1cc(F)c(-c2ccc(OC[C@@H]3CC[C@@H](OC4CCCCO4)CC3)cc2)cc1=O)(C(=O)O)S(C)(=O)=O,,CCO,,Cl,[Li+].[OH-],test
US20080167314A1,Cc1cc(-c2nc3cccnn3c2-c2ccnc(N)c2)ccc1F.O=C(Cl)c1cccnc1Cl>>Cc1cc(-c2nc3cccnn3c2-c2ccnc(NC(=O)c3cccnc3Cl)c2)ccc1F,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20080249130A1,CCOC(=O)c1ccc(C(=O)CBr)cc1.NC(N)=S>>CCOC(=O)c1ccc(-c2csc(N)n2)cc1,,CCO,,,,test
US06369057B1,CN1CCNCC1.O=[N+]([O-])c1c(Cl)ccc(S(=O)(=O)Oc2ccccc2)c1Cl>>CN1CCN(c2ccc(S(=O)(=O)Oc3ccccc3)c(Cl)c2[N+](=O)[O-])CC1,,CC(C)O,,,,test
US20050107449A1,C[Mg]Br.Cc1nc(-c2ccc(C(F)(F)F)cc2)oc1C=O>>Cc1nc(-c2ccc(C(F)(F)F)cc2)oc1C(C)O,,C1CCOC1,,[Cl-].[NH4+],,test
US20090270460A1,CC(C)c1cnn(-c2c(Cl)cccc2Cl)c1CO.Cc1cc(F)ccc1C#N>>Cc1cc(OCc2c(C(C)C)cnn2-c2c(Cl)cccc2Cl)ccc1C#N,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030236230A1,CC(C)(C)OC(=O)N1CCC(C=CC#N)(C2CCCCC2)CC1>>CC(C)(C)OC(=O)N1CCC(CCCN)(C2CCCCC2)CC1,[Ni],CO,,N,,test
US20090018054A1,C[C@H]1C[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1.OCc1cc(C(F)(F)F)ccc1I>>C[C@H]1C[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1cc(C(F)(F)F)ccc1I,,C1CCOC1,,[H-].[Na+],,test
US20140349297A1,Cc1c2ccccc2nc2ccccc12.O=C(CCOS(=O)(=O)C(F)(F)F)OCc1ccccc1>>Cc1c2ccccc2[n+](CCC(=O)OCc2ccccc2)c2ccccc12.O=S(=O)([O-])C(F)(F)F,,ClCCl,,,,test
US20080114006A1,CC(C)n1nc(-c2cccs2)cc1C(=O)O.OC(Cl)C(Cl)Cl.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)n1nc(-c2cccs2)cc1NC(=O)OCC(Cl)(Cl)Cl,,C1COCCO1,,CCN(CC)CC,Cl,test
US20080312286A1,CC1(C2CCCC2)Cc2cc(OCCCCCC#N)c(Cl)c(Cl)c2C1=O.C[Si](C)(C)N=[N+]=[N-]>>CC1(C2CCCC2)Cc2cc(OCCCCCc3nn[nH]n3)c(Cl)c(Cl)c2C1=O,,Cc1ccccc1,,CCCC[Sn](=O)CCCC,,test
US20110144067A1,CC(C)(C)OC(=O)NO.CC1(C)OC[C@@H](CO)O1.O=C(Cl)Cl>>CC(C)(C)OC(=O)NOC(=O)OC[C@@H]1COC(C)(C)O1,,Cc1ccccc1,,,,test
US20090215843A1,C=CCOC(=O)CC(=O)OCC=C.CCOC(=O)CCCCBr>>C=CCOC(=O)C(CCCCC(=O)OCC)C(=O)OCC=C,,C1COCCO1,,[H-].[Na+],,test
US04537890,Cc1cc(Br)cnc1CCCCN.O=c1[nH]c(N[N+](=O)[O-])ncc1Cc1ccn(Cc2ccccc2)c(=O)c1>>Cc1cc(Br)cnc1CCCCNc1ncc(Cc2ccn(Cc3ccccc3)c(=O)c2)c(=O)[nH]1,,c1ccncc1,,,,test
US20030149001A1,CSc1ncc2ccc(=O)n(C3CC3)c2n1.O=S(=O)(c1ccccc1)N1OC1c1ccccc1>>CS(=O)c1ncc2ccc(=O)n(C3CC3)c2n1,,ClCCl,,,,test
US20100056553A1,Br[Mg]C1CC1.CC(C)(C)S(=O)N=C1CCC(O[Si](C)(C)C(C)(C)C)CC1>>CC(C)(C)S(=O)NC1(C2CC2)CCC(O[Si](C)(C)C(C)(C)C)CC1,,CCOCC,,,,test
US05550262,CC(C)C[C@@H](C=O)NC(=O)OCc1ccccc1.CCO.CCOC(OCC)OCC>>CCOC(OCC)[C@H](CC(C)C)NC(=O)OCc1ccccc1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05162318,COC(=O)c1ccc2c(c1)[nH]c(=O)n2CCN(C)C>>CN(C)CCn1c(=O)[nH]c2cc(CO)ccc21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20160083362A1,CC(C)(C)OC(=O)N1CCC[C@@H]1C=O.CCOP(=O)(Cc1cc(F)ccc1Br)OCC>>CC(C)(C)OC(=O)N1CCC[C@@H]1/C=C/c1cc(F)ccc1Br,,C1CCOC1,O,[H-].[Na+],,test
US20030233002A1,Nc1ccc2c(c1)CCC(C(=O)O)O2>>Nc1ccc2c(c1)CCC(CO)O2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04220795,CCOC(=O)CCCCCCCC(C)=O.OCCO>>CCOC1(CCCCCCCC(C)=O)OCCO1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20010012848A1,CC(=O)OC(C)=O.O=C(N[C@@H]1c2cc([N+](=O)[O-])ccc2CC[C@H]1O)c1ccc(Cl)c(Cl)c1>>CC(=O)O[C@@H]1CCc2ccc([N+](=O)[O-])cc2[C@H]1NC(=O)c1ccc(Cl)c(Cl)c1,CN(C)c1ccncc1,C1CCOC1,CCN(CC)CC,,,test
US08273741B2,CC(C)(C#N)c1cccc(C(=O)O)c1.Cc1ccc(N)c(Cl)c1Oc1ccc2nc(NC(=O)C3CC3)cn2n1>>Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)c(Cl)c1Oc1ccc2nc(NC(=O)C3CC3)cn2n1,CN(C)C=O,CN1CCCC1=O,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US20090124613A1,C=C[Mg]Br.O=C(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1C1OCCCO1>>C=CC(O)(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1C1OCCCO1,,C1CCOC1,,,,test
US07138411B2,CO.COc1cccc(CC(=O)O)c1>>COC(=O)Cc1cccc(OC)c1,,CO,,C[Si](C)(C)Cl,,test
US20060167040A1,CCOC(=O)Cn1cc2c(-c3ccc(F)cc3)c(-c3ccncc3)c(-c3ccc(F)cc3)nc2n1>>O=C(O)Cn1cc2c(-c3ccc(F)cc3)c(-c3ccncc3)c(-c3ccc(F)cc3)nc2n1,,CCO,O,[K+].[OH-],,test
US04937343,O=C1c2cc(F)ccc2S(=O)(=O)N1CCCCBr.c1cnc(N2CCNCC2)nc1>>O=C1c2cc(F)ccc2S(=O)(=O)N1CCCCN1CCN(c2ncccn2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06350749B1,Cc1ccccc1.NC1=CC(=O)CC(c2cc(Cl)sc2Cl)C1>>Cc1ccnc2c1C(=O)CC(c1cc(Cl)sc1Cl)C2,,CCO,Cc1ccccc1,[K+].[OH-],,test
US05466661,CON=C(Cl)c1ccccc1OCc1ccc(Cl)cc1Cl.c1c[nH]cn1>>CON=C(c1ccccc1OCc1ccc(Cl)cc1Cl)n1ccnc1,,CN(C)C=O,,CCOCC,[H-].[Na+],test
US20050054645A1,CCC(=O)Cl.COC(Cn1cc(N)c(=O)c(OCc2ccccc2)c1C(=O)NCc1cccc(Cl)c1)OC>>CCC(=O)Nc1cn(CC(OC)OC)c(C(=O)NCc2cccc(Cl)c2)c(OCc2ccccc2)c1=O,,ClC(Cl)Cl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20130274260A1,O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(CCl)c1.OB(O)c1cccc(C(F)(F)F)c1>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2cccc(C(F)(F)F)c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,[I-].[Na+],,test
US20130210800A1,Cc1cnc(-c2cc(N3CCN(C(=O)CCS(C)(=O)=O)CC3)ncc2Cl)c(C)c1>>Cc1cnc(-c2ccnc(N3CCN(C(=O)CCS(C)(=O)=O)CC3)c2)c(C)c1,[Pd],CO,O,[NH4+].[OH-],,test
US20070225260A1,C[C@@H](O)[C@@](C)(CCc1ccc(O[Si](C)(C)C(C)(C)C)cc1)NC(=O)OC(C)(C)C>>C[C@@H](O)[C@@](C)(CCc1ccc(O)cc1)NC(=O)OC(C)(C)C,,CC#N,,CCOC(C)=O,O=C([O-])O.[Na+],test
US20090181942A1,CC(C)I.COc1cccc([C@H]2S[C@H](CC(=O)O)C(=O)Nc3ccc(Cl)cc32)c1Cl>>COc1cccc([C@H]2S[C@H](CC(=O)OC(C)C)C(=O)Nc3ccc(Cl)cc32)c1Cl,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04714786,COc1ccc(/C=C(\C)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1>>C/C(=C\c1ccc(O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C,,CO,,Cl,,test
US05476846,C1=COCCC1.OCCc1ccc(CBr)cc1>>BrCc1ccc(CCOC2CCCCO2)cc1,Cc1ccc(S(=O)(=O)O)cc1,CCOCC,,,,test
US20160200719A1,CC(C)(C)OC(=O)N1CCC(Nc2cnnc3ccc(C(O)(c4ccc(F)cc4)c4ccc(F)cc4)cc23)CC1>>Fc1ccc(C(c2ccc(F)cc2)c2ccc3nncc(NC4CCNCC4)c3c2)cc1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US08906953B2,CN1CC[C@@H](c2c(O)cc(O)c3c(=O)cc(-c4cccc([N+](=O)[O-])c4)oc23)[C@@H]1CO.Cl>>CN1CC[C@@H](c2c(O)cc(O)c3c(=O)cc(-c4cccc([N+](=O)[O-])c4)oc23)[C@@H]1CO.Cl,,CO,,,,test
US20020133007A1,COc1c(Cl)cc(F)c(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c1[N+](=O)[O-]>>COc1c(Cl)cc(F)c(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c1N,[Fe],CC(=O)O,,O,,test
US20160229860A1,C#Cc1cnc2ccc(Cl)nn12.OB(O)c1ccc(CN2CCOCC2)cc1>>C#Cc1cnc2ccc(-c3ccc(CN4CCOCC4)cc3)nn12,,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20130045963A1,BrCCBr.COC(=O)Cc1cc(OC2CCC3(CC2)OCCO3)nc(C(F)(F)F)n1>>COC(=O)C1(c2cc(OC3CCC4(CC3)OCCO4)nc(C(F)(F)F)n2)CC1,,C1CCOC1,,[H-].[Na+],,test
US20160016948A1,CC(C)(C)OC(=O)N1CC[C@@H](S(C)(=O)=O)[C@H](F)C1>>CS(=O)(=O)[C@@H]1CCNC[C@H]1F,,ClCCl,,Cc1ccccc1,O=C(O)C(F)(F)F,test
US20070219195A1,O=C(OO)c1cccc(Cl)c1.O=c1c2ccccc2c(Br)nn1-c1ccc(Sc2ccccc2)cc1>>O=c1c2ccccc2c(Br)nn1-c1ccc(S(=O)c2ccccc2)cc1,,ClCCl,,,,test
US20090105253A1,C#CC(=O)OCC.CCOc1cc(C(=O)OC)ccc1N=[N+]=[N-]>>CCOC(=O)c1cn(-c2ccc(C(=O)OC)cc2OCC)nn1,,Cc1ccccc1,,,,test
US20120157428A1,CS(=O)(=O)Cl.Cc1noc(CO)c1-c1cn(C)nc1C(=O)c1ccc(Cl)cc1>>Cc1noc(COS(C)(=O)=O)c1-c1cn(C)nc1C(=O)c1ccc(Cl)cc1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20070249607A1,CC(C)(C)OC(=O)N1CCC(CO)(c2ccccc2)CC1.COc1ccc(-c2nnn(C)n2)cc1CBr>>COc1ccc(-c2nnn(C)n2)cc1COCC1(c2ccccc2)CCN(C(=O)OC(C)(C)C)CC1,,CN(C)C=O,,[H-].[Na+],,test
US09334304B2,C1CCOC1.CCOP(=O)(Cc1ccc(C(=O)OC)cc1)OCC.C[O-].O=Cc1ccc(C=O)cc1>>COC(=O)c1ccc(/C=C/c2ccc(/C=C/c3ccc(C(=O)OC)cc3)cc2)cc1,,C1CCOC1,,Cl,,test
US20060223801A1,Cc1[nH]c(C(=O)O)cc1Br.NC(=O)c1cc(Cl)nc(N2CCC(O)CC2)c1>>Cc1[nH]c(C(=O)OC2CCN(c3cc(C(N)=O)cc(Cl)n3)CC2)cc1Br,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070203072A1,COC(=O)C1=CC(=O)CC1C(=O)OC>>COC(=O)C1=CC(O)CC1C(=O)OC,,CO,,[BH4-].[Na+],,test
US20130331378A1,COC(=O)c1cccc(Cc2c(-c3ccccc3)nn3ccccc23)c1>>O=C(O)c1cccc(Cc2c(-c3ccccc3)nn3ccccc23)c1,,CO,,Cl,[K+].[OH-],test
US20160031879A1,CCOC(=O)c1cc(CC2CCCO2)n2cccc(Cl)c12>>O=C(O)c1cc(CC2CCCO2)n2cccc(Cl)c12,,CO,O,[K+].[OH-],,test
US20020019429A1,CC(C)(C)OC(=O)N[C@H](CC(=O)OCc1ccccc1)C(=O)N[C@H](COC(=O)OCc1ccccc1)c1ccccc1.CNC(=O)[C@@H](NC(=O)[C@@H](CC(=O)OCc1ccccc1)n1ccc(-c2ccccc2)c1)C(C)(C)C.COC1CC(c2ccc(-c3ccncc3)cc2)C(OC)O1>>O=C(C[C@H](C(=O)N[C@H](COC(=O)OCc1ccccc1)c1ccccc1)n1ccc(-c2ccc(-c3ccncc3)cc2)c1)OCc1ccccc1,,ClCCCl,,CO,ClCCl,test
US20060205715A1,CC1(C)CC(=O)c2ccc(Oc3ccc(C#N)cn3)cc21.OO>>CC1(C)CC(=O)c2ccc(Oc3ccc(C(N)=O)cn3)cc21,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US05861437,Cc1cccc(CCCO)c1O.O=S(Cl)Cl>>Cc1cccc(CCCCl)c1O,CN(C)C=O,C1CCOC1,,c1ccncc1,,test
US20020032168A1,CC(C)(C)OC(=O)NCCN(C1CCCC1)C1CCCC1.Cl>>Cl.NCCN(C1CCCC1)C1CCCC1,,ClCCl,,,,test
US05576319,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N#Cc1ccc2cc(Cl)ccc2n1>>CC(C)(C)OC(=O)NCC1CCc2cc(Cl)ccc2N1,O=[Pt]=O,CO,,,,test
US20080182854A1,C1COCCN1.CC(C)(C)[Si](C)(C)OCc1cccc(CCC(=O)O)n1>>CC(C)(C)[Si](C)(C)OCc1cccc(CCC(=O)N2CCOCC2)n1,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US20090227648A1,Fc1ccc([C@H]2CO2)cc1.Nc1ccc(Cl)c(Br)c1>>OC[C@H](Nc1ccc(Cl)c(Br)c1)c1ccc(F)cc1,,CC#N,,O,,test
US20150152068A1,CO[C@@H]1C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1>>CO[C@@H]1C[C@@H](CO)N(C(=O)OC(C)(C)C)C1,,C1CCOC1,CCOC(C)=O,O,,test
US20160272628A1,CC(C)(C)OC(=O)NCCBr.CC1NS(=O)(=O)c2ccc(Br)cc21>>CC1c2cc(Br)ccc2S(=O)(=O)N1CCNC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05462941,Clc1nnc(-c2ccco2)c2ccccc12.c1c[nH]cn1>>c1coc(-c2nnc(-n3ccnc3)c3ccccc23)c1,,CN1CCCC1=O,,,,test
US20120295884A1,CC(=O)c1c[nH]c2cc(CC(=O)O)ccc12.CO>>COC(=O)Cc1ccc2c(C(C)=O)c[nH]c2c1,,CO,,C[Si](C)(C)C=[N+]=[N-],,test
US20130116234A1,COC(=O)c1c(CC(F)(F)F)nc2ccc(Cl)cc2c1-c1ccccc1>>O=C(O)c1c(CC(F)(F)F)nc2ccc(Cl)cc2c1-c1ccccc1,,c1ccncc1,,[I-].[Li+],,test
US20050153998A1,CI.c1ccc(CN2CCC3(CC2)CNc2ncccc23)cc1>>CN1CC2(CCN(Cc3ccccc3)CC2)c2cccnc21,,CN(C)C=O,,[H-].[Na+],,test
US05039805,CC(C)(C)OC(=O)C[C@H](NC(=O)c1cccc(NC(=O)C(Cc2ccc(C(=N)N)cc2)NC(=O)OC(C)(C)C)c1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)O.O=C(O)C(F)(F)F>>N=C(N)c1ccc(CC(N)C(=O)Nc2cccc(C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc3cccc4ccccc34)C(=O)O)c2)cc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20130331460A1,C#C[Si](C)(C)C.COc1cc(CBr)cc(OC)c1>>COc1cc(CC#C[Si](C)(C)C)cc(OC)c1,,C1CCOC1,CCOCC,CC[Mg]Br,,test
US20120277325A1,CC1CC(=O)C2=C(C1)C(C)(C)C(C)CC2(C)C.CC1CC(=O)C2C(C1)C(C)(C)C(C)CC2(C)C.N=CN>>CC1CC2C(c3ncncc31)C(C)(C)CC(C)C2(C)C,[Pd],CCCCO,,CC(=O)O,[H][H],test
US20020103141A1,CCOC(=O)/C=C/C(F)(F)F.O=Cc1ccc(O)c(C=O)c1>>CCOC(=O)C1=Cc2cc(C=O)ccc2OC1C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04873253,CC(C)(C)OC(=O)N[C@@H](Cc1cccc(Oc2ccccc2)c1)C(=O)O.Nc1ccncn1>>CC(C)(C)OC(=O)NC(Cc1cccc(Oc2ccccc2)c1)C(=O)Nc1ccncn1,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US04975439,CC1CCCC(C)N1C(=O)CCCCl.COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCNC[C@H]1OC>>COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(CCCC(=O)N2C(C)CCCC2C)C[C@H]1OC,,CC(=O)CC(C)C,O,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US05082847,CC(=O)O.COc1ccc(O)cc1.O=[N+]([O-])O>>COc1ccc(OC(C)=O)cc1[N+](=O)[O-],,CC(=O)O,,CC(=O)OC(C)=O,,test
US20090137561A1,COc1cc(-c2ccc(CO)cc2C2=CCCC2(C)C)c(F)cn1.O=S(Cl)Cl>>COc1cc(-c2ccc(CCl)cc2C2=CCCC2(C)C)c(F)cn1,,ClCCl,,CN(C)C=O,,test
US20100286390A1,C[C@H]1[C@H](Nc2cn[nH]c(=O)c2Br)C[C@@H]2C[C@H]1C2(C)C.O=C1c2ccccc2C(=O)N1CCBr>>C[C@H]1[C@H](Nc2cnn(CCN3C(=O)c4ccccc4C3=O)c(=O)c2Br)C[C@@H]2C[C@H]1C2(C)C,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20090054644A1,CC(Oc1ccc(C#N)cn1)C1CNCC1c1ccc(Cl)c(Cl)c1.O=C(Cl)CBr>>CC(Oc1ccc(C#N)cn1)C1CN(C(=O)CBr)CC1c1ccc(Cl)c(Cl)c1,,ClCCl,,CCN(CC)CC,,test
US20160272617A1,COCCOCCOCCOCCN.Cc1cc(C(=O)O)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1>>COCCOCCOCCOCCNC(=O)c1ccc(-c2ccc(C[C@H](NC(=O)[C@@H]3CC[C@@H](CNC(=O)OC(C)(C)C)CC3)C(=O)Nc3ccc(-c4nn[nH]n4)cc3)cc2)c(C)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050070592A1,COC(=O)CBr.Cc1c(Cc2ccccc2)c2cc(-c3ccc(O)cc3)ccc2n1Cc1ccccc1>>COC(=O)COc1ccc(-c2ccc3c(c2)c(Cc2ccccc2)c(C)n3Cc2ccccc2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160039821A1,C=O.CCOC(=O)c1cc2c(-c3cc(CS(C)(=O)=O)ccc3Nc3ccc(F)cc3)cn(C)c(=O)c2[nH]1>>CCOC(=O)c1[nH]c2c(=O)n(C)cc3c2c1CN(c1ccc(F)cc1)c1ccc(CS(C)(=O)=O)cc1-3,,CO,,Cl,,test
US05552558,CCN(CC)C(N)=S.CCOC(=O)C(=O)CBr>>CCOC(=O)c1csc(N(CC)CC)n1,,CC(C)=O,,O=S(=O)([O-])[O-].[Mg+2],,test
US20070135490A1,CS(=O)(=O)OCc1cccc(CCOC2CCCCO2)c1.OCCc1ccccc1>>c1ccc(CCOCc2cccc(CCOC3CCCCO3)c2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20070129347A1,CCOC(=O)CC1CCC(c2ccccc2)(N(C)C)CC1.Nc1ccc(F)cc1>>CN(C)C1(c2ccccc2)CCC(CC(=O)Nc2ccc(F)cc2)CC1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20050038065A1,CCOC(=O)c1c[nH]c2ccc(OCC)nc2c1=O.CN(C)C=O.NCc1ccccc1>>CCOc1ccc2[nH]cc(C(=O)NCc3ccccc3)c(=O)c2n1.CN(C)C=O,,CN(C)C=O,,,,test
US20130172384A1,NC[C@@H]1CCN(C(=O)C2CC2)C1.NNC(=O)c1ccc(Br)cc1F.O=C(n1ccnc1)n1ccnc1>>O=C(NC[C@@H]1CCN(C(=O)C2CC2)C1)NNC(=O)c1ccc(Br)cc1F,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20150018335A1,Brc1ccc2c(c1)OCO2.C1CCOC1.CCOC(=O)C1CCN(C(=O)OC(C)(C)C)CC1.[Li]C(C)(C)C>>CC(C)(C)OC(=O)N1CCC(C(O)(c2ccc3c(c2)OCO3)c2ccc3c(c2)OCO3)CC1,,C1CCOC1,,,,test
US20100035883A1,CCOC(OCC)c1cccc(C2Nc3cccc4c(=O)[nH]nc(c34)C2c2cccc(C(OCC)OCC)c2)c1>>O=Cc1cccc(C2(c3cccc(C=O)c3)Cc3n[nH]c(=O)c4cccc(c34)N2)c1,,Cl,,O=C([O-])[O-].[K+].[K+],,test
US20110065681A1,CCCC[Sn](CCCC)(CCCC)c1ccc(C)cn1.COC(=O)c1cc(Br)cc(C(=O)OC)c1>>COC(=O)c1cc(C(=O)OC)cc(-c2ccc(C)cn2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20110009394A1,CC(C)(C)OC(=O)NC1CCNCC1.COc1ccc2ncc(=O)n(CC[C@H]3CO3)c2n1>>COc1ccc2ncc(=O)n(CC[C@H](O)CN3CCC(NC(=O)OC(C)(C)C)CC3)c2n1,,CN(C)C=O,,,,test
US20100331326A1,Cc1cc(Cl)nc2ccc(Br)cc12.O=C1NCCN1c1cccnc1>>Cc1cc(Cl)nc2ccc(N3CCN(c4cccnc4)C3=O)cc12,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=C([O-])[O-].[K+].[K+],test
US20090298836A1,COC(=O)c1cccc2cnncc12>>O=C(O)c1cccc2cnncc12,,O,,C1CCOC1,[Li+].[OH-],test
US20070173486A1,Clc1ccccc1C(OC1CCNCC1)c1ccccc1Cl.O=C=Nc1cccc(Cl)c1>>O=C(Nc1cccc(Cl)c1)N1CCC(OC(c2ccccc2Cl)c2ccccc2Cl)CC1,,ClCCl,,CCN(CC)CC,,test
US04473395,CCCO.Cc1ncc(-c2ccc(Cl)cc2)cc1C(=O)O>>CCCOC(=O)c1cc(-c2ccc(Cl)cc2)cnc1C,,CCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090306139A1,CCc1ccc(C2CC(C(=O)O)CN(C(=O)N3CCOCC3)C2)cc1.O=S(Cl)Cl>>CCc1ccc(C2CC(C(=O)Cl)CN(C(=O)N3CCOCC3)C2)cc1,,ClCCl,,,,test
US20060281771A1,CC(C)c1ccc(NC(=O)OC2CCNCC2)cc1.COc1cc2ncc(C#N)c(Cl)c2cc1OC>>COc1cc2ncc(C#N)c(N3CCC(OC(=O)Nc4ccc(C(C)C)cc4)CC3)c2cc1OC,,CC(C)O,,,,test
US20130237525A1,OCc1cccc(-n2nccn2)c1>>O=Cc1cccc(-n2nccn2)c1,O=[Mn]=O,ClCCl,,,,test
US05750699,CC(=O)OC(C)=O.Cc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CN)c3Cl)cccn2c1Br>>CC(=O)NCC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20100035880A1,CC(=O)Cl.Cc1ccccc1NS(C)(=O)=O>>CC(=O)c1ccc(NS(C)(=O)=O)c(C)c1,,Cc1ccccc1,ClCCl,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20040063170A1,COCOCCc1ccc(Cc2ccc(OC)cc2O[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)cc1>>COCOCCc1ccc(Cc2ccc(OC)cc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1,,CO,,[Na+].[OH-],,test
US20020062031A1,CCOP(=O)(OCC)c1ccc(CC(NC(=O)OC(C)(C)C)C(=O)OC)cc1P(=O)(OCC)OCC>>CCOP(=O)(OCC)c1ccc(CC(NC(=O)OC(C)(C)C)C(=O)O)cc1P(=O)(OCC)OCC,,C1CCOC1,O,[Li+].[OH-],,test
US20160264567A1,CC(C)(C)OC(=O)N([K])C(=O)OC(C)(C)C.CS(=O)(=O)OCc1cc(Cl)cnc1Cl>>CC(C)(C)OC(=O)N(Cc1cc(Cl)cnc1Cl)C(=O)OC(C)(C)C,,CCOC(C)=O,CN(C)C=O,[I-].[Na+],,test
US05827887,CC(C)N(C(=O)CBr)C(C)C.Oc1ccc(I)cc1>>CC(C)N(C(=O)COc1ccc(I)cc1)C(C)C,,C1CCOC1,,[H-].[Na+],,test
US20150152108A1,FC(F)(F)c1cccc(-c2ccc3c(n2)N[C@H]2CCN3C2)c1.S=C=Nc1cccc(-c2cnco2)c1>>FC(F)(F)c1cccc(-c2ccc3c(n2)N(C(=S)Nc2cccc(-c4cnco4)c2)[C@H]2CCN3C2)c1,,CN(C)C=O,,CO,[H-].[Na+],test
US20120283288A1,CC(C)(C)c1cc(C(=O)O)n(-c2cccc(F)c2)n1.Cn1c(=O)[nH]c2nccc(Oc3ccc(N)c(F)c3)c21.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cn1c(=O)[nH]c2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)nn4-c4cccc(F)c4)c(F)c3)c21,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,,test
US20130190312A1,COc1cnc(Oc2cc(C)c(-c3csc(N)n3)c(C)c2)nc1.O=C(Cl)c1ccncc1>>COc1cnc(Oc2cc(C)c(-c3csc(NC(=O)c4ccncc4)n3)c(C)c2)nc1,,ClCCl,,CCN(CC)CC,Cl,test
US20040053957A1,NC(=O)c1sc2nccc(OS(=O)(=O)C(F)(F)F)c2c1N.c1ccc(CN2CCNCC2)cc1>>NC(=O)c1sc2nccc(N3CCN(Cc4ccccc4)CC3)c2c1N,,C1COCCO1,,,,test
US04189485,CCN.Clc1cccc(Cl)c1Cn1cnc2c(Cl)ncnc21>>CCNc1ncnc2c1ncn2Cc1c(Cl)cccc1Cl,,CO,,,,test
US20070105943A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.COC(=O)c1ccc(N)c(I)c1>>COC(=O)c1ccc(N)c(C(C)=O)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O,,test
US20160023991A1,CCOC(=O)CCCCCOc1ccccc1CN(CCOC)C(=O)c1ccc(-c2ccco2)cc1>>COCCN(Cc1ccccc1OCCCCCC(=O)O)C(=O)c1ccc(-c2ccco2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US06423707B1,Cc1ncc([N+](=O)[O-])n1CCO.O=C(O)c1cc(-c2ccccc2)nc2ccccc12>>CCOC(=O)c1cc(-c2ccccc2)nc2ccccc12.Cc1ncc([N+](=O)[O-])[nH]1,CN(C)c1ccncc1,C1CCOC1,,CCN=C=NCCCN(C)C,,test
US20060183785A1,CC(=O)c1cccc(-c2ccccc2C(F)(F)F)c1.COC(OC)N(C)C>>CN(C)C=CC(=O)c1cccc(-c2ccccc2C(F)(F)F)c1,,CN(C)C=O,,,,test
US20070161686A1,COc1cc(N)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1.O=C(O)c1ccsc1>>COc1cc(NC(=O)c2ccsc2)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20090192156A1,COC1CCN(C(=O)c2cc(/C=C3\OC(=O)c4ccc(Cl)cc43)ccc2F)CC1.NN>>COC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(Cl)cc34)ccc2F)CC1,,O,,CN(C)C=O,,test
US20140364414A1,Nc1nccnc1N1CCOCC1.O=C(O)CBr>>Br.Oc1cn2ccnc(N3CCOCC3)c2n1,,CC(C)O,,,,test
US04112095,FC(F)(F)c1ccc(-c2ccc(Cl)nn2)cc1.NNC=O>>FC(F)(F)c1ccc(-c2ccc3nncn3n2)cc1,,CCCCO,,,,test
US04929741,C#CC(=O)OC.COc1ccc(OC)c(C=O)c1>>COC(=O)C#CC(O)c1cc(OC)ccc1OC,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20160009702A1,C[Mg]Cl.Cc1ccc(Br)cc1C=O>>Cc1ccc(Br)cc1C(C)O,,C1CCOC1,,,,test
US20090082379A1,CC(C)(C)c1ccc(N2C(=O)N(Cc3ccn4oc(=S)nc4c3)C(C)(C)C2=O)cc1.NCCN1CCCC1>>CC(C)(C)c1ccc(N2C(=O)N(Cc3ccnc(NC(=O)NCCN4CCCC4)c3)C(C)(C)C2=O)cc1,,C1COCCO1,,,,test
US04569942,CCOC(=O)C(F)(F)F.O=C1Cc2ccccc2N1>>O=C1Nc2ccccc2C1C(=O)C(F)(F)F,,CCO,,[Na],,test
US04308273,C=CCBr.c1cnc2ccncc2c1>>C=CCN1CCc2ncccc2C1,,CC(C)=O,CO,[BH4-].[Na+],,test
US20070275090A1,OCCOCCOCCCl.[I-]>>OCCOCCOCCI,,CC(C)=O,,O=C([O-])O.[Na+],,test
US20160222033A1,CC1(C)OB(C2=CCCCC2)OC1(C)C.Cc1sc(N)nc1Br>>Cc1sc(N)nc1C1=CCCCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20160000078A1,C#Cc1ccccc1.Cn1oc(=O)nc1/C(=N\OCc1csc(Br)n1)c1ccccc1>>Cn1oc(=O)nc1/C(=N\OCc1csc(C#CC2CC2)n1)c1ccccc1,I[Cu]I,C1CCOC1,,,,test
US20070208010A1,FC(F)(F)c1nnc2cnccn12.OO>>[O-][n+]1ccn2c(C(F)(F)F)nnc2c1,,CC(=O)O,,,,test
US05552405,CC(C)(C)NC(=O)[C@@H]1C[C@H](OCc2ccccc2)CN1C(=O)OC(C)(C)C>>CC(C)(C)NC(=O)[C@@H]1C[C@H](OCc2ccccc2)CN1,,C1COCCO1,Cl,,,test
US04352748,CC(=O)Cl.Cc1ccc2c(c1)C(C)(C)C(C)C2C(C)C>>CC(=O)c1cc2c(cc1C)C(C)(C)C(C)C2C(C)C,,C[N+](=O)[O-],,[Al+3].[Cl-].[Cl-].[Cl-],,test
US05990209,C=CCCCCCCCCCBr.CC1(C)CCCC(C)(C)N1>>C=CCCCCCCCCCN1C(C)(C)CCCC1(C)C,,CN1CCCC1=O,,[I-].[K+],,test
US20080306107A1,CCOC(=O)CBr.Cc1cc(C(F)(F)F)c(C#N)c(=S)[nH]1>>CCOC(=O)c1sc2nc(C)cc(C(F)(F)F)c2c1N,,CCO,,C,C[O-].[Na+],test
US20030166639A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(F)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1ccc(F)cc1[N+](=O)[O-],,ClCCl,,O=C(O)C(F)(F)F,,test
US03933839,CNCC=O.CS(=O)c1nnc(N=C=O)s1>>CN(CC=O)C(=O)Nc1nnc(S(C)=O)s1,,c1ccccc1,,,,test
US06800778B1,BrCCBr.CCOC(=O)CC(=O)c1ccccc1>>CCOC(=O)C1(C(=O)c2ccccc2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040254159A1,COC(=O)Cc1ccc(Nc2cc(Cl)ccc2C(=O)OC)c([N+](=O)[O-])c1>>COC(=O)Cc1ccc(Nc2cc(Cl)ccc2C(=O)OC)c(N)c1,[Pt],CCOC(C)=O,,CO,[H][H],test
US07157487B2,COC(=O)Cc1ccc([N+](=O)[O-])c(O)c1.Cc1ccccc1N=C=S>>COC(=O)Cc1ccc2nc(Nc3ccccc3C)oc2c1,[Pd],CCO,,,,test
US06127550,CCC(N)CO.Cc1ccc(S(=O)(=O)Cl)cc1>>CC[C@@H]1CN1S(=O)(=O)c1ccc(C)cc1,,COC(C)(C)C,,O,[Na+].[OH-],test
US20160051523A1,CC(C)(C)OC(=O)Nc1nc(/C(=N/OC2(C(=O)OC(c3ccccc3)c3ccccc3)CC2)C(=O)N[C@@H]2C(=O)N(S(=O)(=O)O)[C@@H]2Cn2cncn2)cs1>>Nc1nc(/C(=N/OC2(C(=O)O)CC2)C(=O)N[C@@H]2C(=O)N(S(=O)(=O)O)[C@@H]2Cn2cncn2)cs1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110275611A1,N#Cc1ccc(-c2cc(N3CCOC(c4nc(-c5cccc(Cl)c5)c[nH]4)C3)nc(N)n2)cc1F.NN>>Nc1nc(-c2ccc3c(N)n[nH]c3c2)cc(N2CCOC(c3nc(-c4cccc(Cl)c4)c[nH]3)C2)n1,,CCO,,CC#N,O,test
US20110288117A1,Nc1cc([N+](=O)[O-])ccn1.O=C(Cl)C1CC1>>O=C(Nc1cc([N+](=O)[O-])ccn1)C1CC1,,c1ccncc1,,,,test
US20030139445A1,ClCc1c(Cl)cccc1Cl.[O-][n+]1ccccc1S>>[O-][n+]1ccccc1SCc1c(Cl)cccc1Cl,,CCO,,[Na],,test
US20090325954A1,CN(C)CCN.O=C(O)c1ccc(-c2cc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)cc1>>CN(C)CCNC(=O)c1ccc(-c2cc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)cc1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030022886A1,CI.COc1cc(I)cc(OC)c1OCCO>>COCCOc1c(OC)cc(I)cc1OC,,C1CCOC1,,O,[H-].[Na+],test
US20010041709A1,CCOC(=O)[C@H](Cc1ccc(OC/C=C/C#Cc2ccccc2)cc1)OCC>>CCO[C@@H](Cc1ccc(OC/C=C/C#Cc2ccccc2)cc1)C(=O)O,,CCO,,[Na+].[OH-],,test
US04138564,O=C1Nc2cccnc2N2CCN(C(=O)OCc3ccccc3)CC12>>O=C1Nc2cccnc2N2CCNCC12,[Pd],CCO,,,,test
US20160184310A1,CC(C)(C)OC(=O)N1CC=C(c2cnc(N)c(C#N)c2)CC1>>CC(C)(C)OC(=O)N1CCC(c2cnc(N)c(C#N)c2)CC1,[Pd],CO,,,,test
US06995179B2,C=C1CC(=O)O1.O=C(CO)Nc1ccccc1>>CC(=O)CC(=O)OCC(=O)Nc1ccccc1,,Cc1ccccc1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20160206616A1,CC(C)(C)OC(=O)N1CC(F)C(C)(C)C1CO>>CC(C)(C)OC(=O)N1CC(F)C(C)(C)C1C=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20100168105A1,CC(C)(C)OC(=O)CBr.O=C(C1CC12CCNCC2)N1CCN(C2CCC2)CC1>>CC(C)(C)OC(=O)CN1CCC2(CC1)CC2C(=O)N1CCN(C2CCC2)CC1,,C1CCOC1,,,,test
US05288748,CCCN(CCC)C1CCc2ccc([N+](=O)[O-])c(Cl)c2C1>>CCCN(CCC)C1CCc2ccc(N)cc2C1,[Pd],CO,N,CCN(CC)CC,,test
US20160137653A1,N[C@@H]1CC[C@@H](c2ccccc2)CC1.O=C=Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)N[C@@H]1CC[C@@H](c2ccccc2)CC1,,CCOCC,,,,test
US20100240642A1,CCOC(=O)c1c(-c2ccc(C(C)(C)C)cc2)c2ccccc2n1Cc1cccc(Br)c1.CSc1ccc(B(O)O)cc1>>CSc1ccc(-c2cccc(Cn3c(C(=O)O)c(-c4ccc(C(C)(C)C)cc4)c4ccccc43)c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20050054850A1,Cc1cc(Nc2cccc(C(=O)CCN3CCC(Cc4ccccc4)CC3)c2)c2ccccc2n1.OCCCO>>Cc1cc(Nc2cccc(C3(CCN4CCC(Cc5ccccc5)CC4)OCCCO3)c2)c2ccccc2n1,,CCOC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US20090247507A1,Nc1ncc(Br)c(N2CCN(Cc3ccncc3)CC2)c1[N+](=O)[O-].O=Cc1ccc(OCCN2CCOCC2)cc1>>Brc1cnc2[nH]c(-c3ccc(OCCN4CCOCC4)cc3)nc2c1N1CCN(Cc2ccncc2)CC1,,CCO,CCO,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20050267093A1,CCN(CC)CCOc1ccc([N+](=O)[O-])cc1Br>>CCN(CC)CCOc1ccc(N)cc1Br,,CCOC(C)=O,,CO,ClCCl,test
US20070043001A1,CCN(C=C(C(=O)c1ccc(C)cc1)c1ccccc1)CC.N#CCC(N)=O>>Cc1ccc(-c2[nH]c(=O)c(C#N)cc2-c2ccccc2)cc1,,CN(C)C=O,CO,Cl,[H-].[Na+],test
US05990105,CCN(CC)CCCN.Nc1ccc(S(=O)(=O)c2cc(Br)nc(Br)c2)cc1>>CCN(CC)CCCNc1cc(S(=O)(=O)c2ccc(N)cc2)cc(Br)n1,,C1COCCO1,,,,test
US20100261732A1,O=C(CCN1CCN(c2cccc([N+](=O)[O-])c2)CC1)NNC(=O)NCC1CCCCC1>>O=c1[nH]nc(CCN2CCN(c3cccc([N+](=O)[O-])c3)CC2)n1CC1CCCCC1,,[Na+],[OH-],Cl,,test
US06599917B1,CI.O[C@@H]1CN(c2cc(Cc3ccccc3)c(Br)cn2)C[C@H]1O>>CO[C@@H]1CN(c2cc(Cc3ccccc3)c(Br)cn2)C[C@H]1O,,C1CCOC1,,[H-].[Na+],,test
US20150376170A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1COc2cc(F)ccc2N1>>CC(C)(C)OC(=O)N1C(=O)COc2cc(F)ccc21,CN(C)c1ccncc1,C1CCOC1,,CCOC(C)=O,,test
US04263291,C=O.COC(=O)C(=NO)c1cnsc1>>O=C(O)C(=O)c1cnsc1,,O,,Cl,,test
US20130317000A1,CC(C)(C)OC(=O)c1cc(Cl)c(COc2ccc3c(c2)OC(C)(C)CC3)cc1F>>CC1(C)CCc2ccc(OCc3cc(F)c(C(=O)O)cc3Cl)cc2O1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040138255A1,CC(C)(COc1ccc(N)cc1)COc1ccc(N)cc1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(COc1ccc(NS(=O)(=O)C(F)(F)F)cc1)COc1ccc(NS(=O)(=O)C(F)(F)F)cc1,,ClCCl,,O=C([O-])O.[Na+],,test
US20130158005A1,CN(c1ccccc1CCc1ccnc(Cl)n1)S(C)(=O)=O.Nc1ccc2c(c1)CCC(=O)N2>>CN(c1ccccc1CCc1ccnc(Nc2ccc3c(c2)CCC(=O)N3)n1)S(C)(=O)=O,,CCCCO,,,,test
US20050049310A1,COC(=O)[C@H](Cc1ccc(Br)cc1)NC(=O)c1cc(Cl)ccc1N.O=Cc1cccc2ccccc12>>COC(=O)[C@H](Cc1ccc(Br)cc1)NC(=O)c1cc(Cl)ccc1NCc1cccc2ccccc12,,ClCCl,,,,test
US04009169,COC(=O)C1CCCc2cccnc21.N>>NC(=O)C1CCCc2cccnc21,,CO,,,,test
US20150038438A1,Cn1c(CO[Si](C)(C)C(C)(C)C)cc2cc3c(cc21)N(C(=O)OC(C)(C)C)CCC=CC3=O>>Cn1c(CO[Si](C)(C)C(C)(C)C)cc2cc3c(cc21)N(C(=O)OC(C)(C)C)CCCCC3=O,[Pd],CCOC(C)=O,,,,test
US20130102776A1,COc1ccc2c(c1C#CCCC1CCN(C(=O)OC(C)(C)C)CC1)OCC2=O.O=Cc1n[nH]c2ccccc12>>COc1ccc2c(c1C#CCCC1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccccc13)C2=O,C1CCNCC1,CO,,,,test
US20110313176A1,CCCN(CCc1cccs1)[C@H]1CCc2c(O)cccc2C1>>CCCN(CCc1cccs1)[C@H]1CCc2c(O)cccc2C1,,O,,Cl,N,test
US20080234261A1,CCn1c(-c2nonc2N)nc2cnc(Cc3cccc(C(=O)OC)c3)cc21>>CCn1c(-c2nonc2N)nc2cnc(Cc3cccc(C(=O)O)c3)cc21,,CO,O,[Li+].[OH-],,test
US05534481,Cn1cc2ccccc2n1.O=S(O)O.[Li]CCCC>>Cn1nc2ccccc2c1S(=O)[O-].[Li+],,CCOCC,,CCCCCC,,test
US20120308920A1,C=C(C)C(=O)Cl.CC(C)(C)OC(=O)C1C2CC3C(OC(=O)C31)C2O>>C=C(C)C(=O)OC1C2CC3C1OC(=O)C3C2C(=O)OC(C)(C)C,,O,,CC#N,CCN(CC)CC,test
US20110009407A1,O=C(Nc1ccncc1)c1cccn(C2CCc3c(Cl)cccc32)c1=O.OB(O)c1ccccc1>>O=C(Nc1ccncc1)c1cccn(C2CCc3c(-c4ccccc4)cccc32)c1=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US05296495,CC(=O)OC(C)=O.CC(C)(C)NCc1csc(-c2cc3cc(O)ccc3o2)n1>>CC(=O)N(Cc1csc(-c2cc3cc(O)ccc3o2)n1)C(C)(C)C,,CCOC(C)=O,,,,test
US20140336106A1,COC(=O)C(CC#N)C[C@H](NC(=O)OC(C)(C)C)C(=O)OC>>COC(=O)C(CCN)C[C@H](NC(=O)OC(C)(C)C)C(=O)OC,[Pd],CC(=O)O,,,,test
US20160083400A1,C=C(C)c1nccc(C(=O)OC)c1N>>COC(=O)c1ccnc(C(C)C)c1N,[Pd],CCOC(C)=O,CO,,,test
US04605652,COc1cc(OC)c(C(=O)Cl)cc1Br.NC1CN2CCC1CC2>>COc1cc(OC)c(C(=O)NC2CN3CCC2CC3)cc1Br.Cl,,C1CCOC1,,,,test
US05665718,CCN(CC)Cc1nc(-c2ncn3c2CN(C)C(=O)c2c-3ccc(F)c2Cl)no1.Cl>>CCN(CC)Cc1nc(-c2ncn3c2CN(C)C(=O)c2c-3ccc(F)c2Cl)no1.Cl,,CCO,,CCOCC,,test
US20150141427A1,CC1(C)OB(c2cncnc2)OC1(C)C.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OCCO)c(Br)c1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OCCO)c(-c2cncnc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,Cc1ccccc1,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20090247746A1,CCOC(=O)c1cc2cc(OC(F)(F)F)cc(N(C)S(=O)(=O)c3cccs3)c2n1COC>>CN(c1cc(OC(F)(F)F)cc2cc(C(=O)O)[nH]c12)S(=O)(=O)c1cccs1,,CCO,,C1CCOC1,Cl,test
US04820331,CCCC(=O)C1=C(O)CC(COC(C)(C)C)CC1=O>>CCCC(=O)C1=C(O)CC(CO)CC1=O,,CCO,,Cl,,test
US20150232481A1,Fc1cc(F)c(OCc2ccccc2)c(CCI)c1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>Fc1cc(F)c(OCc2ccccc2)c(CC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c1.[I-],,Cc1ccccc1,,,,test
US20150045359A1,CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(N)cc2)C1.O=C1CCC(=O)N1Cl>>CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(N)c(Cl)c2)C1,,CN(C)C=O,,CCOC(C)=O,,test
US20020001591A1,N=C(N)NCCC[C@H](N)C(=O)O.O=C(Cl)C1CCCCC1>>N=C(N)NCCC[C@H](NC(=O)C1CCCCC1)C(=O)O,,[Na+],[OH-],Cl,,test
US05658938,COc1cccc(CCC(=O)c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)c1OC>>COc1cccc(CCC(=O)c2c[nH]cn2)c1OC,,O=CO,,,,test
US20080207590A1,COC(=O)c1ccccc1O.O=[N+]([O-])c1ccc(Cl)cc1F>>COC(=O)c1ccccc1Oc1cc(Cl)ccc1[N+](=O)[O-],,CC#N,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20040034004A1,COC(=O)c1cc(-c2cc(C=O)ccc2OC(F)(F)F)c2c(c1)C(C)(C)CO2>>CC1(C)COc2c(-c3cc(C=O)ccc3OC(F)(F)F)cc(C(=O)O)cc21,,CO,,[K+].[OH-],,test
US20090082434A1,Cc1ccc(S(=O)(=O)OCC2Cc3cccc(Br)c3O2)cc1.OB(O)c1ccc(F)cc1>>Cc1ccc(S(=O)(=O)OCC2Cc3cccc(-c4ccc(F)cc4)c3O2)cc1,Cc1ccccc1[P](c1ccccc1C)(c1ccccc1C)[Pd](Cl)(Cl)[P](c1ccccc1C)(c1ccccc1C)c1ccccc1C,,,O=C([O-])[O-].[K+].[K+],,test
US20090253687A1,O=C(OO)c1cccc(Cl)c1.O=C1COc2ccc(C3=Cn4ccnc4SC3c3ccccc3)cc2N1>>O=C1COc2ccc(C3=Cn4ccnc4S(=O)C3c3ccccc3)cc2N1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])O.[Na+],test
US20070179172A1,Cc1ccc([C@H]2Nc3ccc(S(N)(=O)=O)cc3[C@H]3C=CC[C@H]32)cc1>>Cc1ccc([C@H]2Nc3ccc(S(N)(=O)=O)cc3[C@H]3CCC[C@H]32)cc1,[Pd],C1CCOC1,CCO,,,test
US20110245272A1,c1cc(C2CO2)ccn1.c1cnc2[nH]c3c(c2c1)C1CCCN1CC3>>OC(Cn1c2c(c3cccnc31)C1CCCN1CC2)c1ccncc1,,CN(C)C=O,,[H-].[Na+],,test
US20140194415A1,CNC(=O)Cc1ccc(Br)cc1F.O=C1CCC(=O)N1Br>>CNC(=O)C(Br)c1ccc(Br)cc1F,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20160039844A1,C=CCN1CCOc2ccc(-c3c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc4cc(C(=O)OCC)nn34)c(Cl)c21>>C=CCN1CCOc2ccc(-c3c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc4cc(C(=O)O)nn34)c(Cl)c21,,CCO,,[Na+].[OH-],,test
US20040242564A1,CN(Cc1ccccc1)c1cc(N=C=O)ccn1.COc1cc2c(cc1OC)C(Cc1ccc(F)cc1)N(CCNC(=O)OC(C)(C)C)CC2>>COc1cc2c(cc1OC)C(Cc1ccc(F)cc1)N(CCNC(=O)Nc1ccnc(N(C)Cc3ccccc3)c1)CC2,,Cc1ccccc1,ClCCl,O=C(O)C(F)(F)F,,test
US20130059834A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](C#N)C1.O=C(O)C(F)(F)F>>N#C[C@@H]1CC[C@@H](N)C1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20060160864A1,CC1CCN(c2ccc(Br)cc2C=O)CC1.CCOC(=O)C(C)P(=O)(OCC)OCC>>CCOC(=O)/C(C)=C/c1cc(Br)ccc1N1CCC(C)CC1,,Cc1ccccc1,,O,[H-].[Na+],test
US20030045728A1,CCOC(=O)CC(c1ccccc1)c1c[nH]c2cc(OCCCNc3ccccn3)ccc12>>CCOC(=O)CC(c1ccccc1)c1c[nH]c2cc(OCCCNC3=NCCCC3)ccc12,[Pd],,,Cl,,test
US20080221101A1,COC(=O)C1CCN(c2ccc(C=O)cc2NC(=O)c2cc(C)on2)CC1.C[C@@H](N)c1ccccc1>>COC(=O)C1CCN(c2ccc(CN[C@H](C)c3ccccc3)cc2NC(=O)c2cc(C)on2)CC1,,CCOC(C)=O,ClCCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05932599,CCN.Nc1ccc(S(=O)(=O)Nc2cc(Cl)nc(N)n2)cc1>>CCNc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(N)n1,,CCO,,,,test
US05256673,COC(=O)c1ccc2c(c1)c(CCCCN1CC=C(c3ccccc3)CC1)cn2S(=O)(=O)c1ccccc1>>O=C(O)c1ccc2[nH]cc(CCCCN3CC=C(c4ccccc4)CC3)c2c1,,CCO,O,[K+].[OH-],,test
US20110130379A1,C[C@@H]1CNCCN1C(=O)OC(C)(C)C.O=S(=O)(Cl)c1ccc(Cl)cc1>>C[C@@H]1CN(S(=O)(=O)c2ccc(Cl)cc2)CCN1,,ClCCl,,CCN(CC)CC,,test
US20090088459A1,NCc1cnc(Br)s1.O=S(=O)(Cl)c1ccccc1Cl>>O=S(=O)(NCc1cnc(Br)s1)c1ccccc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20140135277A1,C=CCOC[C@H]1OC(O)(c2ccc(Cl)c(Cc3ccc(OCC)cc3)c2)[C@H](OCC=C)[C@@H](OCC=C)[C@@H]1OCC=C>>C=CCOCC(=O)[C@@H](OCC=C)[C@H](OCC=C)[C@@H](OCC=C)C(=O)c1ccc(Cl)c(Cc2ccc(OCC)cc2)c1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20110263612A1,Nc1ccc(-c2cc3c(cc2Cl)OCC3)cn1.O=C(Cl)c1c(F)cccc1F>>O=C(Nc1ccc(-c2cc3c(cc2Cl)OCC3)cn1)c1c(F)cccc1F,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20110098479A1,CC(C)[C@H](N)CO.O=C1CCCO1>>CC(C)[C@H]1COC(CCCO)=N1,,Clc1ccccc1,,,,test
US20060154975A1,CCCI.O=C(O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>CCCOC(=O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,CCOC(C)=O,CS(C)=O,O,[K+].[OH-],test
US20030055244A1,CNCC(=O)O.O=C1CCN(Cc2ccccc2)CC1>>CN(CC(=O)O)C1CCN(Cc2ccccc2)CC1,,ClCCCl,,CC(=O)O,,test
US20030171377A1,COC(=O)[C@H](Cc1ccc(O)cc1)n1cccc1.OCCSc1nc2ccccc2s1>>COC(=O)[C@H](Cc1ccc(OCCSc2nc3ccccc3s2)cc1)n1cccc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100087429A1,C[Mg]Br.O=c1[nH]ccc2oc3ccc(-c4cccnc4)cc3c(=O)c12>>C=C1c2cc(-c3cccnc3)ccc2Oc2cc[nH]c(=O)c21,,C1CCOC1,ClCCCl,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20140323562A1,O=C(OO)c1cccc(Cl)c1.c1coc(CSSCc2ccco2)c1>>O=S(Cc1ccco1)SCc1ccco1,,ClCCl,,,,test
US05256675,CC(=O)Nc1ncc(Sc2nnnn2C)s1>>Cn1nnnc1Sc1cnc(N)s1,,CCO,,Cl,,test
US20060004021A1,CC(OS(C)(=O)=O)c1nnn(-c2cccc(Cl)c2)n1.S=c1[nH]nc(-c2ccncc2)n1C1CC1>>CC(Sc1nnc(-c2ccncc2)n1C1CC1)c1nnn(-c2cccc(Cl)c2)n1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04173650,COc1ccccc1C(=O)CBr.[C-]#N>>COc1ccccc1C(=O)CC#N,,O,,CCO,,test
US04672066,CCCc1c(OCCBr)ccc(C(C)=O)c1O.CCOC(=O)c1ccc(O)cc1>>CCCc1c(OCCOc2ccc(C(=O)OCC)cc2)ccc(C(C)=O)c1O,,CC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100280083A1,COc1cc(-c2noc(C)n2)c(SC)cc1OCc1ccccc1.O=C(OO)c1cccc(Cl)c1>>COc1cc(-c2noc(C)n2)c(S(C)(=O)=O)cc1OCc1ccccc1,,ClCCl,,O=S([O-])O.[Na+],,test
US08629147B2,CCOC(=O)c1c[nH]nc1N.COc1ccc2c(c1)CCc1cnc(Cl)nc1-2>>CCOC(=O)c1cn(-c2ncc3c(n2)-c2ccc(OC)cc2CC3)nc1N,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100160308A1,COC(OC)c1cc(F)c([N+](=O)[O-])cc1OS(C)(=O)=O>>O=Cc1cc(F)c([N+](=O)[O-])cc1O,,CS(C)=O,O,Cl,[K+].[OH-],test
US20080306115A1,CC(C)(C)[Si](C)(C)Cl.Cc1c(C(=O)N[C@H]2CCCC[C@H]2N)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(O)cc1>>Cc1c(C(=O)N[C@H]2CCCC[C@H]2N)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(O[Si](C)(C)C(C)(C)C)cc1,,ClCCl,,O,,test
US20040167160A1,CC(=O)c1cc2c(I)cccc2s1.CCCOc1c(B(O)O)cc(C(C)C)cc1C(C)C>>CCCOc1c(-c2cccc3sc(C(C)=O)cc23)cc(C(C)C)cc1C(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],test
US20140249129A1,N#Cc1ccc(C2C3=C(CCCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C(=O)Oc2ccc([N+](=O)[O-])cc2)cc1.NC1CCSCC1>>N#Cc1ccc(C2C3=C(CCCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C(=O)NC2CCSCC2)cc1,,CC#N,,,,test
US05296478,O=C1Cc2ccccc2N1N1CCOCC1.O=Cc1ccncc1>>O=C1C(Cc2ccncc2)c2ccccc2N1N1CCOCC1,,CO,,CCN(CC)CC,,test
US06071903,COC(=O)[C@@H](N)CO.O=S(=O)(Cl)c1ccc(Oc2ccncc2)cc1>>COC(=O)C(CO)NS(=O)(=O)c1ccc(Oc2ccncc2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US04362728,CS(N)(=O)=O.FC(F)(F)CN=C=S>>CS(=O)(=O)NC(=S)NCC(F)(F)F,,CC(C)=O,O,[Na+].[OH-],,test
US20130165483A1,CC(=O)Nc1cc(-c2cc(-c3ccccc3C)c(C(N)=O)n2COCC[Si](C)(C)C)ccn1.COC(OC)N(C)C.NN>>CC(=O)Nc1cc(-c2cc(-c3ccccc3C)c(-c3nnc[nH]3)n2COCC[Si](C)(C)C)ccn1,,Cc1ccccc1,,O,,test
US03984403,NCCCC[C@H](N)C(=O)O>>NCCCCC(N)C(=O)O,,O,,Cl,,test
US06833387B1,BrBr.CCOC(=O)c1cc2ccccc2[nH]1>>CCOC(=O)c1[nH]c2ccccc2c1Br,,CN(C)C=O,,O,,test
US20110245205A1,OC(c1ncc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)s1)C1CC1>>O=C(c1ncc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)s1)C1CC1,,CCOC(C)=O,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04367338,C=CC(=O)CCCCC.Cn1c(=O)[nH][nH]c1=O>>CCCCCC(=O)CCn1[nH]c(=O)n(C)c1=O,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20150025056A1,COC(=O)[C@H]1C[C@H](O)CN(Cc2ccccc2)[C@@H]1C(=O)OCc1ccccc1>>COC(=O)[C@H]1C[C@H](O)CN[C@@H]1C(=O)O,[Pd],CO,,[H][H],,test
US20090143361A1,COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)cc(Cl)c4)n3c2n1.OB(O)c1ccc(OC(F)(F)F)cc1>>COc1ccc2nc(C)c3c(C)nc(-c4ccc(OC(F)(F)F)cc4)n3c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20130090337A1,COCCCCNc1ccccc1[N+](=O)[O-]>>COCCCCNc1ccccc1N,[Pd],Cc1ccccc1,,,,test
US20140080808A1,CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(C3(c4ccc(-c5ncco5)cc4)CC3)n2CCS1>>CC1(CO)Cc2nnc(C3(c4ccc(-c5ncco5)cc4)CC3)n2CCS1,,CO,,Cl,,test
US05877325,O=C(Cl)CCl.O=C1CCCN1>>O=C(CCl)N1CCCC1=O,,Cc1ccccc1,,,,test
US20080004302A1,CC(C)Oc1cc(Nc2nc(NCc3cc(C(N)=O)no3)ncc2Br)[nH]n1>>CC(C)Oc1cc(Nc2ccnc(NCc3cc(C(N)=O)no3)n2)[nH]n1,[Pd],CCO,,[H][H],,test
US20020102405A1,CC(C)(C)OC(=O)COCCOCCOCCOCCOCCOCCN.O=C(Cl)OC(=O)c1ccccc1>>CC(C)(C)OC(=O)COCCOCCOCCOCCOCCOCCNC(=O)OCc1ccccc1,,CCOC(C)=O,O,[Na+].[OH-],,test
US20090143438A1,Cc1c(OCCCCCCCCCO)ccnc1CO.O=S(Cl)Cl>>Cc1c(OCCCCCCCCCO)ccnc1CCl,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US04201724,CCNCC1CC1.O=[N+]([O-])c1cc(C(F)(F)F)c(Cl)c([N+](=O)[O-])c1Cl>>CCN(CC1CC1)c1c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c1[N+](=O)[O-],,COCCOC,,CCN(CC)CC,,test
US20120088752A1,CC(C)(C)OC(=O)N1CCN(C(=O)C2CCN(c3ccc(Cl)c(-c4nc5ccccc5[nH]4)c3)C2)CC1>>O=C(C1CCN(c2ccc(Cl)c(-c3nc4ccccc4[nH]3)c2)C1)N1CCNCC1,,CCOCC,,Cl,,test
US07238716B2,COC(=O)Cc1ccccc1O.Cc1oc(-c2ccccc2)nc1COc1cncc(CO)c1>>COC(=O)Cc1ccccc1OCc1cncc(OCc2nc(-c3ccccc3)oc2C)c1,,C1CCOC1,Cc1ccccc1,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04885302,Cc1cccc(C(=O)OCC2CCN(C(=O)c3cccc(C)c3)CC2)c1>>Cc1cccc(C(=O)N2CCC(CO)CC2)c1,,CCO,O,[K+].[OH-],,test
US04113858,CC(C)(C)OC(=O)N[C@@H](CCC(N)=O)C(=O)O>>NC(=O)CC[C@H](N)C(=O)O,,CN(C)C=O,,,,test
US20050137236A1,BrC(Br)(Br)Br.COC(=O)c1ccc(-c2ccc(OCCO)cc2)cc1SC(C)C>>COC(=O)c1ccc(-c2ccc(OCCBr)cc2)cc1SC(C)C,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20050171180A1,CCC(CC)C(N)c1nccn1Cc1ccccc1.O=S(=O)(Cl)c1ccc(Cl)s1>>CCC(CC)C(NS(=O)(=O)c1ccc(Cl)s1)c1nccn1Cc1ccccc1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20120190665A1,COc1ccc(F)cc1-c1c(NC(=O)c2cnn3cccnc23)cnn1CCOC[Si](C)(C)C>>COc1ccc(F)cc1-c1[nH]ncc1NC(=O)c1cnn2cccnc12,,CCO,O,Cl,,test
US20040037022A1,CC(=O)OC[C@H](Cc1ccc(NC(=O)c2ccccc2)cc1)N(Cc1ccccc1)C[C@@H](COc1ccccc1)OC(C)=O.CI>>CN(C(=O)c1ccccc1)c1ccc(C[C@@H](CO)N(Cc2ccccc2)C[C@H](O)COc2ccccc2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20130310379A1,CNC1CCN(C(=O)OC(C)(C)C)CC1.O=C(O)c1ccc(Oc2ccccc2)cc1>>CN(C(=O)c1ccc(Oc2ccccc2)cc1)C1CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20090076046A1,CCOC(=O)Cl.CN(C)Cc1cn(C(=O)OC(C)(C)C)c2ncc(C#N)cc12>>CC(C)(C)OC(=O)n1cc(CCl)c2cc(C#N)cnc21,,Cc1ccccc1,,O,,test
US20140378459A1,CCOC(=O)c1cccc(CNCC(=O)OC(C)(C)C)n1.O=C(Cl)OCc1ccccc1>>CCOC(=O)c1cccc(CN(CC(=O)OC(C)(C)C)C(=O)OCc2ccccc2)n1,,C1CCOC1,,O,O=C([O-])O.[Na+],test
US20160000760A1,CS/C(=N\C#N)Nc1cc(Cl)c(-c2ccc(OCCCC#N)cc2)c(Cl)c1.NN>>N#CCCCOc1ccc(-c2c(Cl)cc(Nc3n[nH]c(N)n3)cc2Cl)cc1,,CO,,,,test
US20160200704A1,COC(=O)c1cc(Cc2cc(C(=O)O)ccn2)cc2cc(Cl)cnc12.Cc1nc(N)ccc1CN>>COC(=O)c1cc(Cc2cc(C(=O)NCc3ccc(N)nc3C)ccn2)cc2cc(Cl)cnc12,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080103125A1,COC(=O)c1c(C)nc(C(F)(F)F)nc1C>>Cc1nc(C(F)(F)F)nc(C)c1C(=O)O,,CCO,O,[K+].[OH-],,test
US20030162818A1,CC(C)(C)c1ccc(COc2cccc(C(=O)Nc3ccccc3S(N)(=O)=O)c2)cc1.CCCCCC(=O)Cl>>CCCCCC(=O)NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCc2ccc(C(C)(C)C)cc2)c1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20100069388A1,CC(C)(C)OC(=O)NCCNc1ncc(C=O)cc1Cl.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)/C=C/c1cnc(NCCNC(=O)OC(C)(C)C)c(Cl)c1,,C1CCOC1,O,CCOC(C)=O,[H-].[Na+],test
US20160016948A1,CC(C)n1cnc2cnc(Nc3ccnc(Cl)n3)cc21.OC1CCNCC1>>CC(C)n1cnc2cnc(Nc3ccnc(N4CCC(O)CC4)n3)cc21,,CC(C)O,O,CCN(CC)CC,,test
US05273972,O=C1C2CCN(CC2)C1CN1CCCCC1>>OC1C2CCN(CC2)C1CN1CCCCC1,,CCO,,[BH4-].[Na+],,test
US05624961,CNCCOc1cc(C)c(O)cc1C(C)C.Cc1c(C)c(OCCO)c(CCl)c(C)c1O.Cl>>Cc1cc(OCCN(C)Cc2c(C)c(O)c(C)c(C)c2OCCO)c(C(C)C)cc1O.Cl,,CN(C)C=O,,CCN(CC)CC,,test
US20120172382A1,CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Cl.Cn1cc(-c2cnccc2Oc2cc(F)c(N)cc2Cl)cn1>>CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1cc(Cl)c(Oc2ccncc2-c2cnn(C)c2)cc1F,,ClCCl,c1ccncc1,,,test
US20130196960A1,OCc1cc2scnc2[nH]1>>Cc1cc2scnc2[nH]1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20100298336A1,Cc1cc(O)nc(S)n1.Clc1cncc(Cl)c1CBr>>Cc1cc(O)nc(SCc2c(Cl)cncc2Cl)n1,,CCO,,CCN(CC)CC,,test
US20120289501A1,CC(C)C(=O)O.Nc1ncnc2c1c(-c1ccc3c(c1)OC(c1ccccc1)CC3)cn2[C@H]1CC[C@@H](N)CC1>>CC(C)C(=O)N[C@@H]1CC[C@H](n2cc(-c3ccc4c(c3)OC(c3ccccc3)CC4)c3c(N)ncnc32)CC1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140171412A1,CON(C)C(=O)CBr.Cn1c(=O)c2c(-c3cccc(C#N)c3)n(CC(O)CO[Si](C)(C)C(C)(C)C)cc2n(C)c1=O>>CON(C)C(=O)COC(CO[Si](C)(C)C(C)(C)C)Cn1cc2c(c1-c1cccc(C#N)c1)c(=O)n(C)c(=O)n2C,,C1CCOC1,,[H-].[Na+],,test
US20050107399A1,COc1c(N)cc(C(C)(C)C)cc1NS(C)(=O)=O.O=C(O)C(=O)c1ccc(Oc2ccnc(N3CCOCC3)n2)c2ccccc12>>COc1c(NC(=O)C(=O)c2ccc(Oc3ccnc(N4CCOCC4)n3)c3ccccc23)cc(C(C)(C)C)cc1NS(C)(=O)=O,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20020019402A1,COC(=O)C1CC(=O)N(c2cccc(CO)c2)C1>>COC(=O)C1CC(=O)N(c2cccc(C=O)c2)C1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20120053175A1,COc1cc(-c2cnc3c(c2)C(=Cc2ccncc2)C(=O)N3)cc(OC)c1OC>>COc1cc(-c2cnc3c(c2)C(Cc2cccnc2)C(=O)N3)cc(OC)c1OC,[Pd],CO,,O=C[O-].[NH4+],,test
US20060111375A1,CC(=O)Cl.CCCc1ccc(O)cc1>>CCCc1ccc(OC(C)=O)cc1,,ClCCl,,c1ccncc1,,test
US20050027121A1,CC1(C)COCCN1N.Cc1ccc(C[C@@H]2CN(CCC=O)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C.Cl.Cl>>Cc1ccc(C[C@@H]2CN(CCC=NN3CCOCC3(C)C)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C.Cl.Cl,,ClCCl,,CCN(CC)CC,,test
US20060074119A1,CN(C)CCCO.COC(=O)c1sc(-n2cnc3cc(OC)c(O)cc32)cc1OCc1ccccc1C(F)(F)F>>COC(=O)c1sc(-n2cnc3cc(OC)c(OCCCN(C)C)cc32)cc1OCc1ccccc1C(F)(F)F,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110065681A1,Brc1nccs1.COC(=O)c1cc(O)cc(-c2ccc(C)cc2C#N)c1>>COC(=O)c1cc(Oc2nccs2)cc(-c2ccc(C)cc2C#N)c1,,CCOC(C)=O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US04994459,O=[N+]([O-])c1ccc(OCC(O)CN2CCN(c3ncccn3)CC2)cc1>>Nc1ccc(OCC(O)CN2CCN(c3ncccn3)CC2)cc1,[Pd],CCOC(C)=O,,Cl,Cl,test
US04801717,O=S(=O)(CCl)c1ccccc1.O=[N+]([O-])c1ccc(F)cc1>>O=[N+]([O-])c1ccc(F)cc1CS(=O)(=O)c1ccccc1,,CS(C)=O,,,,test
US20070281963A1,COc1cc2[nH]c(=O)c3c(N)n(-c4cc(OCc5ccccc5)ccc4C)nc3c2cc1OC>>COc1cc2[nH]c(=O)c3c(N)n(-c4cc(O)ccc4C)nc3c2cc1OC,[Pd],CCOC(C)=O,,CO,[H][H],test
US20110190329A1,C=CCBr.N[C@@H]1CCc2ccccc21>>C=CCN[C@@H]1CCc2ccccc21,,ClCCl,,CCN(CC)CC,,test
US06323370B1,CCCNCCC.O=CC=Cc1ccccc1>>CCCN(CC=Cc1ccccc1)CCC,,ClCCCl,,,,test
US04358588,CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccc(O)cc3)[C@H]2SC1.CN(C)C=O>>CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccc(O)cc3)[C@H]2SC1.O,,CN(C)C=O,,,,test
US20100298324A1,COc1cc2c(=O)n(-c3ncc(OC)c(OC)n3)c(=S)[nH]c2cc1C(=O)O.NCc1ccncc1>>COc1cc2c(=O)n(-c3ncc(OC)c(OC)n3)c(=S)[nH]c2cc1C(=O)NCc1ccncc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020115620A1,CO.N#Cc1ccc(-n2cccn2)cc1F>>O=Cc1ccc(-n2cccn2)cc1F,,CCOC(C)=O,Cc1ccccc1,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US05157038,CC1(O)NC(=O)OC12CCN(Cc1ccccc1)CC2>>C=C1NC(=O)OC12CCN(Cc1ccccc1)CC2,,C1COCCO1,,,,test
US05066675,CC#CCO.CC(C)(CC(=O)Cl)Cc1ccc(Cl)cc1>>CC#CCOC(=O)C(c1ccc(Cl)cc1)C(C)(C)C,CN(C)c1ccncc1,,,C1CCOC1,,test
US20060246228A1,CC(C)(Br)C(=O)Br.CC(C)(C(=O)c1ccc(Sc2ccccc2)cc1)N1CCOCC1>>CC(C)(Br)C(=O)c1ccc(Sc2ccc(C(=O)C(C)(C)N3CCOCC3)cc2)cc1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20110257151A1,COC(=O)c1ccc2c(c1)CC(C)(C)C(c1ccc([N+](=O)[O-])cc1)N2>>COC(=O)c1ccc2c(c1)CC(C)(C)C(c1ccc(N)cc1)N2,[Fe],CO,O,,,test
US20160096839A1,COc1cc(Cl)ncn1.Cc1ccc(N)c(B2OC(C)(C)C(C)(C)O2)c1>>COc1cc(-c2cc(C)ccc2N)ncn1,,CCO,O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US05872137,CCOc1ccc(C(=O)O)cc1.ClC(Cl)=CCOc1cc(Cl)c(OCCCBr)c(Cl)c1>>CCOc1ccc(C(=O)OCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150141465A1,CCn1nccc1NC(C)C.O=C(Cl)CCl>>CCn1nccc1N(C(=O)CCl)C(C)C,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,O,test
US20030187053A1,CN(Cc1ccccc1)C(=O)[C@@H](N)c1ccccc1.Cn1c(C(=O)O)cc2cc(NC(=O)c3ccccc3O)ccc21>>CN(Cc1ccccc1)C(=O)[C@@H](NC(=O)c1cc2cc(NC(=O)c3ccccc3O)ccc2n1C)c1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20150252059A1,C=CCCBr.CC(C#N)S(C)(=O)=O>>C=CCCC(C)(C#N)S(C)(=O)=O,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040106520A1,CC(C)(C)c1cc[nH]n1.O=C1C(O)SCN1c1cccc(C(F)(F)F)c1>>CC(C)(C)c1ccn(C2SCN(c3cccc(C(F)(F)F)c3)C2=O)n1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120220622A1,NC(=O)CNCc1ccc(Br)cc1.O=C(n1ccnc1)n1ccnc1>>O=C1CN(Cc2ccc(Br)cc2)C(=O)N1,CN(C)c1ccncc1,CC#N,O,,,test
US20060229280A1,CCOC(=O)CC(=O)c1ccc(OC)cc1.O=[N+]([O-])C=Cc1ccc2c(c1)OCO2>>CCOC(=O)C(C(=O)c1ccc(OC)cc1)C(C[N+](=O)[O-])c1ccc2c(c1)OCO2,,CCOC(C)=O,,C1CCC2=NCCCN2CC1,,test
US20030149001A1,C=C(OCC)c1c(C)c2cnc(Nc3ccc(N4CCC(O)CC4)cn3)nc2n(C2CCCC2)c1=O>>CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCC(O)CC4)cn3)nc2n(C2CCCC2)c1=O,,ClC(Cl)Cl,,Cl,,test
US20120035196A1,COC(=O)Cc1cccc(-c2c(C)cc(OCCCN)cc2C)c1C.CS(=O)(=O)Cl>>COC(=O)Cc1cccc(-c2c(C)cc(OCCCNS(C)(=O)=O)cc2C)c1C,,ClCCl,,CCN(CC)CC,,test
US20110319378A1,CC[C@@H](CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)N1C(=O)[C@@](C)(C2CC2C(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1>>CC[C@@H](CO)N1C(=O)[C@@](C)(C2CC2C(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04073894,O=S(Cl)Cl.O=c1on(-c2ccc(Cl)c(Cl)c2)c(=O)n1CO>>O=c1on(-c2ccc(Cl)c(Cl)c2)c(=O)n1CCl,,Cc1ccccc1,ClC(Cl)Cl,,,test
US20110230555A1,CCCCCCCOCCCCCCN.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCCCCCCOCCCCCCN=C=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05484551,C/C=C/C(=O)Oc1ccc(C(=O)O)cc1.N#Cc1ccc(O)cc1F>>C/C=C/C(=O)Oc1ccc(C(=O)Oc2ccc(C#N)c(F)c2)cc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20160009710A1,Brc1cnccc1OCC12CC3CC(CC(C3)C1)C2.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1ccc(OCC23CC4CC(CC(C4)C2)C3)c(Br)c1,,ClCCl,,,,test
US20130131039A1,CCOP(=O)(CC#N)OCC.O=CC1CC1(F)F>>N#CC=CC1CC1(F)F,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20100009969A1,CC1CCCN1.O=C(NC1CCc2sc(-c3ccc(OCCCCl)cc3)nc21)OCc1ccccc1>>CC1CCCN1CCCOc1ccc(-c2nc3c(s2)CCC3NC(=O)OCc2ccccc2)cc1,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US06071903,COC(=O)C(CO)N(Cc1ccccc1NC(=O)C(F)(F)F)S(=O)(=O)c1ccc(OC)cc1>>C=C(C(=O)OC)N(Cc1ccccc1NC(=O)C(F)(F)F)S(=O)(=O)c1ccc(OC)cc1,,ClCCl,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US20120196884A1,C=O.CN(c1ccc(NC(=O)Nc2ccccc2)cc1)S(=O)(=O)c1ccc(C2CCNCC2)s1>>CN1CCC(c2ccc(S(=O)(=O)N(C)c3ccc(NC(=O)Nc4ccccc4)cc3)s2)CC1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20070265265A1,CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)Nc1nc(-c2ccc(C(=O)O)cc2)cs1.NC1CC1>>CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)Nc1nc(-c2ccc(C(=O)NC3CC3)cc2)cs1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06127414,C[C@@H](NC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)C(c1ccccc1)c1ccccc1)c1ccccc1.Cl>>C[C@@H](NC(=O)[C@H](CCCN)NC(=O)C(c1ccccc1)c1ccccc1)c1ccccc1.Cl,[Pd],CO,,CC(=O)O,,test
US20160222033A1,CCN(Cc1cc(=O)n2c(CCCO)c(C)sc2n1)c1ccc(F)cc1.CI>>CCN(Cc1cc(=O)n2c(CCCOC)c(C)sc2n1)c1ccc(F)cc1,,C1CCOC1,,[H-].[Na+],,test
US20160194288A1,CC(C)(C)OC(=O)NC(=N)N.O=C(CBr)CCCCCc1ccccc1>>CC(C)(C)OC(=O)n1cc(CCCCCc2ccccc2)nc1N,,CN(C)C=O,,O,,test
US20090221653A1,O=C(O)COCCc1cccc2ccccc12>>OCCOCCc1cccc2ccccc12,,C1CCOC1,,CO,,test
US20110152240A1,N#Cc1cccc(C(=O)O)c1.Nc1cc(NC2CC2)n2ncc(C=O)c2n1>>N#Cc1ccc(C(=O)Nc2cc(NC3CC3)n3ncc(C=O)c3n2)cc1,,CC#N,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06034121,CCCCS.CCCc1c(Cl)c2cc(Br)ccc2oc1=O>>CCCCSc1c(CCC)c(=O)oc2ccc(Br)cc12,,CCO,,[Na],,test
US04710221,CCOc1ccc(C(=O)OC)c(SC(=O)N(C)C)c1>>CCOc1ccc(C(=O)OC)c(S)c1,,CO,,C[O-].[Na+],,test
US20090181928A1,C[Si](C)(C)CCN1C(=O)CN(c2ccc(CCN)cc2OCc2ccccc2)S1(=O)=O.O=S(=O)(Cl)CC1CCCCC1>>C[Si](C)(C)CCN1C(=O)CN(c2ccc(CCNS(=O)(=O)CC3CCCCC3)cc2OCc2ccccc2)S1(=O)=O,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US04933330,CCOC(=O)c1cc(N=Cc2ccccc2)ccc1OC(C)=O>>CCOC(=O)c1cc(N)ccc1OC(C)=O,,CCO,O,,,test
US05616594,Cn1nc(-c2c(F)cccc2Cl)nc1-c1ccc(CBr)c(Cl)c1.Oc1ccc(OC(F)(F)F)cc1>>Cn1nc(-c2c(F)cccc2Cl)nc1-c1ccc(COc2ccc(OC(F)(F)F)cc2)c(Cl)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20030216417A1,CCOC(=O)Cl.COc1cc2ncnc(Nc3ccc(F)c(N)c3)c2cc1OC>>CCOC(=O)Nc1cc(Nc2ncnc3cc(OC)c(OC)cc23)ccc1F,,ClCCl,,CCN(CC)CC,,test
US20100273755A1,C=CC(=O)CNc1ccc(CC(=O)OC)cc1.O=C(Nc1ccccc1-c1ccccc1)OC1CCNCC1>>COC(=O)Cc1ccc(NCC(=O)CCN2CCC(OC(=O)Nc3ccccc3-c3ccccc3)CC2)cc1,,CCO,,,,test
US20110263598A1,C[Si](C)(C)CCOCn1nc(/C=C/c2ccncc2)c2ccc([C@@H]3C[C@@]34C(=O)Nc3ccccc34)cc21>>O=C1Nc2ccccc2[C@]12C[C@H]2c1ccc2c(/C=C/c3ccncc3)n[nH]c2c1,,ClCCl,,CCOCC,FB(F)F,test
US20080108613A1,CC(=O)OC(C)=O.OCCNCCOc1n[nH]c2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12>>CC(=O)N(CCO)CCOc1n[nH]c2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12,,CC(=O)N(C)C,,O,,test
US20120041030A1,Cc1c[n+]([O-])ccc1S.OCCCCCCCCBr>>Cc1c[n+]([O-])ccc1SCCCCCCCCO,,CCOC(C)=O,O,CCO,[Na+].[OH-],test
US20120149684A1,CC(C)Cc1c[nH]c(C2CCN(C(=O)OC(C)(C)C)CC2)n1.ClCCN1CCCC1>>CC(C)Cc1cn(CCN2CCCC2)c(C2CCN(C(=O)OC(C)(C)C)CC2)n1,,CS(C)=O,,Cl,[K+].[OH-],test
US05102890,O=C(O)CCN1CCCCC1=O.O=C1c2ccccc2C(Cl)N1c1ccc2ccc(Cl)nc2n1>>O=C(CCN1CCCCC1=O)OC1c2ccccc2C(=O)N1c1ccc2ccc(Cl)nc2n1,,CN(C)C=O,,C1CCC2=NCCCN2CC1,O,test
US05070089,CSC(=S)N1CCNCC1.Cc1ccccc1CCl>>CSC(=S)N1CCN(Cc2ccccc2C)CC1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20020052512A1,O=C(O)C1CCNCC1.O=C(OCC1c2ccccc2-c2ccccc21)ON1C(=O)CCC1=O>>O=C(O)C1CCN(C(=O)OCC2c3ccccc3-c3ccccc32)CC1,,C1CCOC1,O,Cl,O=C([O-])O.[Na+],test
US20140073650A1,N=C(NO)c1ccccn1.O=C(Cl)CCl>>ClCc1nc(-c2ccccn2)no1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20140315881A1,Cc1cc(Cl)ccc1C(NC(=O)Cc1ccc(O)c(N)c1)c1ccccc1.Cc1ccnc(C)c1C(=O)O>>Cc1cc(Cl)ccc1C(NC(=O)Cc1ccc(O)c(NC(=O)c2c(C)ccnc2C)c1)c1ccccc1,,ClCCl,O,CCN(C(C)C)C(C)C,O=S(Cl)Cl,test
US20110098302A1,Brc1ccccn1.CCOC(=O)Cc1cccc(Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2CN2C(=O)O[C@H](c3ccccc3)[C@@H]2C)c1>>CCOC(=O)Cc1cccc(Oc2ccc(-c3ccccn3)cc2CN2C(=O)O[C@H](c3ccccc3)[C@@H]2C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20130261086A1,CCN.CCOC(=O)c1nc(Br)ccc1N>>CCNC(=O)c1nc(Br)ccc1N,,CCO,,C1CCOC1,,test
US20160060255A1,CCOc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C3(OCc4ccccc4)CCC3)s2)n1>>CCOc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C3(O)CCC3)s2)n1,,ClCCl,,BrB(Br)Br,,test
US04400202,CCC1(C)CC(=O)N(c2cccc([N+](=O)[O-])c2)C1=O>>CCC1(C)CC(=O)N(c2cccc(N)c2)C1=O,[Fe],O,,CCO,Cl,test
US20160084845A1,NCCS(=O)O.O=C1NC2CSC(CCCCC(=O)ON3C(=O)CCC3=O)C2N1>>O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)NCCS(=O)O,,O,,C1CCOC1,[Na+].[OH-],test
US20100286171A1,O=C(O)c1cnc(CCOC2CCCCO2)cn1.OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>O=C(Nc1cnc(CCOC2CCCCO2)cn1)OCc1ccccc1,,Cc1ccccc1,O,CCN(CC)CC,,test
US20080318929A1,Cc1c(Br)cccc1C(N)=O>>Cc1c(Br)cccc1C#N,,ClCCl,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,c1ccncc1,test
US04119710,N#Cc1cc(C(=O)CNC2CC2)cc(Br)c1N>>N#Cc1cc(C(O)CNC2CC2)cc(Br)c1N,,C1CCOC1,O,[BH4-].[Na+],,test
US20020077271A1,CC(=O)c1cc(N)cc(C(C)=O)c1.Clc1ncnc2nc[nH]c12>>CC(=O)c1cc(Nc2ncnc3nc[nH]c23)cc(C(C)=O)c1,,O,,Cl,[K+].[OH-],test
US05696263,C=C[C@@H](COCOC)OC(C(C)C)(C(C)C)P(=O)(O)O>>C=C[C@@H](CO)OC(C(C)C)(C(C)C)P(=O)(O)O,,CO,,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US20160168097A1,Nc1ccc(C(F)(C(F)(F)F)C(F)(F)Cl)cc1OC(F)F.O=C1CCC(=O)N1Br>>Nc1c(Br)cc(C(F)(C(F)(F)F)C(F)(F)Cl)cc1OC(F)F,,ClCCl,,[Na+].[OH-],,test
US20080045493A1,CCCN1CC(c2ccc(N)cc2)C1.C[C@H](CF)c1ccc(S(=O)(=O)Cl)cc1>>CCCN1CC(c2ccc(NS(=O)(=O)c3ccc([C@H](C)CF)cc3)cc2)C1,,ClCCl,c1ccncc1,,,test
US06288261B1,O=Cc1ccc2ccccc2c1Br>>OCc1ccc2ccccc2c1Br,,CO,,[BH4-].[Na+],,test
US03994867,CCN(CC)CC.CCN=C=O.COCCOC.OCC#CC#CCO>>CCOC(=O)N(CC)CC.OCC#CC#CCO,[Cu],CCN(CC)CC,,,,test
US20030199547A1,COc1cc(-c2cccc(Cl)c2)c2cc(C(=O)c3cncn3C)ccc2n1.c1cscn1>>COc1cc(-c2cccc(Cl)c2)c2cc(C(O)(c3nccs3)c3cncn3C)ccc2n1,,C1CCOC1,CCOCC,CCCCCC,[Li]CCCC,test
US20090069408A1,BrBr.Cc1cccc2c1sc1c(C)cccc12>>Cc1cccc2c1sc1c(C)c(Br)ccc12,,CC(=O)O,,,,test
US20040259873A1,CCOc1cc(C(CCNO)N2Cc3cccc(NC(C)=O)c3C2=O)ccc1OC.O=COCC(F)(F)F>>CCOc1cc([C@@H](CCN(O)C=O)N2Cc3cccc(NC(C)=O)c3C2=O)ccc1OC,,C1CCOC1,,,,test
US04021494,CC1(C)C(=O)C2C=CC1C=C2CCO>>CC1(C)C(=O)C2CCC1CC2CCO,[Pd],CC(C)O,,[H][H],,test
US05922725,CC(=O)c1ccc([N+](=O)[O-])c(Nc2cccc(-c3cccnc3)c2)c1>>CC(=O)c1ccc(Nc2cccc(-c3cccnc3)c2)c(N)c1,[Pd],CCO,ClCCl,CCOCC,,test
US20120295903A1,CC(=O)OCCl.Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCN3CCC(C(=O)OCc4ccccc4)CC3)c2cc1C>>CC(=O)OCn1c(=O)nc2n(CCN3CCC(C(=O)OCc4ccccc4)CC3)c3cc(C)c(C)cc3nc-2c1=O,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090281092A1,BrCc1ccccc1.CCOC(=O)C(C)(O)CNC1CCCCC1>>CCOC(=O)C(C)(O)CN(Cc1ccccc1)C1CCCCC1,,CC#N,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20060154875A1,O=C(OO)c1cccc(Cl)c1.c1ccc2c(c1)cnc1ccsc12>>[O-][n+]1cc2ccccc2c2sccc21,,ClC(Cl)Cl,,,,test
US05684029,CCCCc1nc2ccc(N)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1.O=C(Cl)N1CCCC1>>CCCCc1nc2ccc(NC(=O)N3CCCC3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1,,ClC(Cl)Cl,c1ccncc1,,,test
US20050107355A1,Nc1ccc([N+](=O)[O-])cc1.O=C(O)CCl>>O=C(O)CNc1ccc([N+](=O)[O-])cc1,,O,,,,test
US07977477B2,Nc1cc(C(F)(F)F)cc(Br)c1N.O=C(O)c1n[nH]cc1NCc1c(F)cccc1F>>O=C(Nc1c[nH]nc1-c1nc2c(Br)cc(C(F)(F)F)cc2[nH]1)c1c(F)cccc1F,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US05312829,CC(C)Cc1ccc(O)cc1.CCOC(=O)CCCn1cc(C(=O)c2cccc(CCl)c2)c2ccccc21>>CCOC(=O)CCCn1cc(C(=O)c2cccc(COc3ccc(CC(C)C)cc3)c2)c2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04190579,CCOC(=O)C1CCN1CC(OC)OC.O=O>>COC(CN1CCC1=O)OC,[Zn],C1CCOC1,ClCCl,CC(C)[N-]C(C)C.[Li+],,test
US05849764,C[Mg]Br.O=CCCCc1cccnc1>>CC(O)CCCc1cccnc1,,C1CCOC1,,,,test
US05622954,CC(C)(CC=O)c1ccc(F)cc1.CCCC[SnH](CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)C(O)CC(C)(C)c1ccc(F)cc1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20090029976A1,COC(=O)c1cc2ccc(OC)cc2s1>>COC(=O)c1cc2ccc(O)cc2s1,,ClCCl,,BrB(Br)Br,,test
US04940662,CCO.NCCCC[C@H](N)C(=O)O>>CCOC(=O)[C@@H](N)CCCCN,,O=S(=O)(O)O,,,,test
US04464387,CCN=C=O.O=C(O)CNc1ccccc1>>CCN1C(=O)CN(c2ccccc2)C1=O,,Cc1ccccc1,,,,test
US04000304,C1=CC2=C(N=C3CCCN3C=C2)C(c2c[nH]c3ccccc23)C1.Cl>>C1=CC2=C(N=C3CCCN3C=C2)C(c2c[nH]c3ccccc23)C1.Cl,,CCO,,,,test
US20060014777A1,ClCCl.O=C(O)c1cc(C(F)(F)F)ccc1Cl>>COC(=O)c1cc(C(F)(F)F)ccc1Cl,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20150210688A1,Cc1nn(Cc2ccccc2)cc1CC(F)(F)F>>Cc1n[nH]cc1CC(F)(F)F,[Pd],CO,,Cl,[H][H],test
US20140364604A1,COC(=O)/C=C/C(=O)[O-].OCCCCN1CCOCC1>>COC(=O)/C=C/C(=O)OCCCCN1CCOCC1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20040209905A1,CC(=O)OCCBr.COc1cc2c(Oc3ccc(NC(=O)N(C)C)c(Cl)c3)ncnc2cc1O>>COC(=O)COc1cc2ncnc(Oc3ccc(NC(=O)N(C)C)c(Cl)c3)c2cc1OC,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150245616A1,COC1(C(=O)NCC(F)(F)F)CC(c2cc(F)cc(F)c2)=NO1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COC1(C(=S)NCC(F)(F)F)CC(c2cc(F)cc(F)c2)=NO1,,C1CCOC1,,,,test
US06166219,NC(=O)c1ccc([N+](=O)[O-])c(NC(=O)CCc2ccccc2Cl)c1>>N#Cc1ccc([N+](=O)[O-])c(NC(=O)CCc2ccccc2Cl)c1,Cl[Ti](Cl)(Cl)Cl,C1COCCO1,ClCCl,CCN(CC)CC,,test
US20090247567A1,N#Cc1ccc2c(c1)OCCc1cc(-c3n[nH]c(=O)n3-c3ccccc3Cl)sc1-2.OO>>NC(=O)c1ccc2c(c1)OCCc1cc(-c3n[nH]c(=O)n3-c3ccccc3Cl)sc1-2,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070032481A1,CC(C)(C)OC(=O)N1CCc2nc(Cc3ccccc3)nc(O)c2C1.CC(C)(C)OC(=O)N1CCc2nc(Cc3ccccc3)nc(OS(=O)(=O)C(F)(F)F)c2C1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>Fc1ccc(-c2nc(Cc3ccccc3)nc3c2CNCC3)cc1,,C1CCOC1,O,CC(C)(C)[O-].[K+],,test
US20140031559A1,Cc1ccc(S(=O)(=O)OCCOCCOCCOCCOCCOCCO)cc1.Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1>>Cc1ccc(S(=O)(=O)OCCOCCOCCOCCOCCOCCOC2CCCCO2)cc1,,ClCCl,,,,test
US20160221972A1,COC(=O)c1ccc2c(c1)OCC1(CC1)N(C)C2.NO>>CN1Cc2ccc(C(=O)NO)cc2OCC12CC2,,C1CCOC1,CO,[Na+].[OH-],,test
US05866568,COB(OC)c1cccnc1.COc1nc(C)cnc1NS(=O)(=O)c1cccnc1-c1ccc(I)cc1>>COc1nc(C)cnc1NS(=O)(=O)c1cccnc1-c1ccc(-c2cccnc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20100022513A1,CS/C(=N\C(=O)c1ccccc1)NC(=O)c1ccccc1.NNCc1ccccc1>>O=C(Nc1nc(-c2ccccc2)n(Cc2ccccc2)n1)c1ccccc1,,CN(C)C=O,O,,,test
US20050070542A1,CCC(CC)n1nc(C)c2nc(O)c(C)nc21.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCC(CC)n1nc(C)c2nc(OS(=O)(=O)C(F)(F)F)c(C)nc21,,ClCCl,,CCN(CC)CC,,test
US20070037807A1,CCOC(=O)CCCOC(=O)c1c(C)nc(CC(C)C)c(CNC(=O)OC(C)(C)C)c1-c1ccc(C)cc1>>Cc1ccc(-c2c(CNC(=O)OC(C)(C)C)c(CC(C)C)nc(C)c2C(=O)OCCCC(=O)O)cc1,,CCO,,Cl,[Na+].[OH-],test
US20150152063A1,CC(C)(O)CN.O=C(NC(=S)Nc1n[nH]c2cc(F)ccc12)c1ccc(Cl)cc1>>CC(C)(O)CNC(=NC(=O)c1ccc(Cl)cc1)Nc1n[nH]c2cc(F)ccc12,,C1CCOC1,,ClCCCl,,test
US20030018067A1,CCCCC(=O)c1c(-c2ccc3c(Br)c(O)ccc3c2)oc2ccccc12.CCOC(=O)CBr>>CCCCC(=O)c1c(-c2ccc3c(Br)c(OCC(=O)OCC)ccc3c2)oc2ccccc12,,CN(C)C=O,,[H-].[Na+],,test
US20140275111A1,BrP(Br)Br.OCc1ccc(Br)c(F)c1>>Fc1cc(CBr)ccc1Br,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20160015695A1,CC(C)(C)OC(=O)N1CCC(Nc2c([N+](=O)[O-])cnc3ccsc23)C(O)C1.COCCN(CCOC)S(F)(F)F>>CC(C)(C)OC(=O)N1CCC(Nc2c([N+](=O)[O-])cnc3ccsc23)C(F)C1,,ClCCl,ClCCl,,,test
US20070197588A1,CC(NC(=O)OC(C)(C)C)C1=Cc2ccccc2[C@H](c2ccc(Cl)c(Cl)c2)C1>>CC(NC(=O)OC(C)(C)C)[C@@H]1Cc2ccccc2[C@H](c2ccc(Cl)c(Cl)c2)C1,[Pd],CCOC(C)=O,,,,test
US20100286145A1,COC(=O)c1cc(I)cc(C(=O)N(C)Cc2nc(C)cs2)c1.OB(O)c1ccco1>>COC(=O)c1cc(C(=O)N(C)Cc2nc(C)cs2)cc(-c2ccco2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20130053373A1,C=CC[C@H](COCc1ccccc1)OCC(OCC)OCC>>C=CC[C@H](COCc1ccccc1)OCC=O,,C1CCOC1,,Cl,,test
US20090075938A1,Clc1ccc(CBr)cc1.O=[N+]([O-])c1ccc2oc(=S)[nH]c2c1>>O=[N+]([O-])c1ccc2oc(SCc3ccc(Cl)cc3)nc2c1,,CCOC(C)=O,ClC(Cl)Cl,CCN(CC)CC,,test
US20050282827A1,CCOC(=O)CC(=O)c1ccc(Cl)cc1.CCOC(=O)c1cn[nH]c1N>>CCOC(=O)c1cnn2c(O)cc(-c3ccc(Cl)cc3)nc12,,CCCCCC,,CCOC(C)=O,,test
US20070167598A1,CO.CO[Si](CCl)(OC)OC>>COC[Si](OC)(OC)OC,,CO,,C[O-].[Na+],,test
US20050222230A1,CCc1cc2c(=O)c(-c3ccc(Br)cc3)coc2cc1O.NN>>CCc1cc(-c2n[nH]cc2-c2ccc(Br)cc2)c(O)cc1O,,CCO,,O,,test
US20070249869A1,C[C@@H]([C@@H](CO)NN)C(F)(F)F.Cl>>C[C@@H]([C@H](N)CO)C(F)(F)F.Cl,O=[Pt]=O,CO,Cl,,,test
US20130345123A1,CC(C)(C)OC(=O)N[C@H]1CCCCNC1=O.CC(C)CBr>>CC(C)CN1CCCC[C@H](NC(=O)OC(C)(C)C)C1=O,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20080027068A1,CC(=O)c1nn(C)c(-c2ccc(C(C)(C)C)cc2)c1O.COC(=O)c1ccc(C(=O)NN)cc1O>>COC(=O)c1ccc(C(=O)NN=C(C)c2nn(C)c(-c3ccc(C(C)(C)C)cc3)c2O)cc1O,,CC(C)O,,,,test
US20090318436A1,Fc1cc(-c2cnn(CCOC3CCCCO3)c2)cnc1F.NN>>NNc1ncc(-c2cnn(CCOC3CCCCO3)c2)cc1F,,CC(C)O,O,,,test
US20040116509A1,COC(=O)c1sc(-c2ccccc2)cc1N.O=C(Cl)c1ccc(Cl)cc1>>COC(=O)c1sc(-c2ccccc2)cc1NC(=O)c1ccc(Cl)cc1,,c1ccncc1,,,,test
US05391556,CC1CCN(C(=O)C(Cc2ccc(N)c([N+](=O)[O-])c2)NS(=O)(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)CC1.O=CO>>CC1CCN(C(=O)C(Cc2ccc3[nH]cnc3c2)NS(=O)(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)CC1,[Pd],,,,,test
US20130053409A1,COc1cc(N(C)CCN(C)C(=O)OC(C)(C)C)c([N+](=O)[O-])cc1Nc1nccc(-c2cn(C)c3ccccc23)n1>>COc1cc(N(C)CCN(C)C(=O)OC(C)(C)C)c(N)cc1Nc1nccc(-c2cn(C)c3ccccc23)n1,[Fe],CCO,,O,[Cl-].[NH4+],test
US07179823B1,CCOC(=O)CCc1cn(Cc2ccc3cc(O)ccc3c2)cc1-c1ccccc1.Cc1oc(-c2ccccc2)nc1CCl>>CCOC(=O)CCc1cn(Cc2ccc3cc(OCc4nc(-c5ccccc5)oc4C)ccc3c2)cc1-c1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US04889869,N[C@@H](CCc1ccccc1)C(=O)O>>N[C@@H](CCC1CCCCC1)C(=O)O,,O,,Cl,,test
US20160002241A1,CC(C)(C)OC(=O)Nc1cccc(N)c1.O=[N+]([O-])c1cnc(Cl)nc1Cl>>CC(C)(C)OC(=O)Nc1cccc(Nc2nc(Cl)ncc2[N+](=O)[O-])c1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090192162A1,CCOC(=O)COc1ccc(SCc2cc(O)cc(Br)c2)cc1C.OCC1CC1>>CCOC(=O)COc1ccc(SCc2cc(Br)cc(OCC3CC3)c2)cc1C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US04782064,BrCCCCBr.Nc1ccc2c3c(cccc13)C(=O)NC2=O>>Nc1ccc2c3c(cccc13)C(=O)N(CCCCBr)C2=O,,CN(C)C=O,,O,[H-].[Na+],test
US05220059,COc1ccc(C=O)cc1.COc1ccc2cc(C(C)N)ccc2c1>>COc1ccc(C=N)cc1,,CO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20130116235A1,Cn1cc(-c2ccnc(N3CCc4c(cc5n4CCCC5)C3=O)c2C=O)cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c1=O>>Cn1cc(-c2ccnc(N3CCc4c(cc5n4CCCC5)C3=O)c2CO)cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c1=O,,CO,,[BH4-].[Na+],,test
US20090156603A1,CN(C)CC(=O)Cl.COc1cccc(Sc2cnc(Nc3nc(C4CCNCC4)cs3)c(Oc3ccc(F)cc3Br)c2)c1.Cl.Cl>>COc1cccc(Sc2cnc(Nc3nc(C4CCN(C(=O)CN(C)C)CC4)cs3)c(Oc3ccc(F)cc3Br)c2)c1.Cl.Cl,,ClCCl,,CCN(CC)CC,,test
US05399578,CCCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1)[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OCc1ccccc1>>CCCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OCc1ccccc1,,C1COCCO1,,Cl,,test
US05652257,COC(=O)[C@@H]1CCC(=O)N1Cc1ccc([N+](=O)[O-])cc1>>O=C(O)[C@@H]1CCC(=O)N1Cc1ccc([N+](=O)[O-])cc1,,CO,,O,[Na+].[OH-],test
US20070270587A1,COC[C@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2.OCCCO>>COC[C@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C1(OCCCO1)C(=O)N2,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20070099925A1,CC(C)(CN)CO.Cc1nccn2c(-c3ccnc(S(C)(=O)=O)n3)c(-c3ccc(F)cc3)nc12>>Cc1nccn2c(-c3ccnc(NCC(C)(C)CO)n3)c(-c3ccc(F)cc3)nc12,,CC#N,,,,test
US20060009443A1,COC1=NCCN(C(=O)OC(C)(C)C)C1c1nc(-c2cccc(Cl)c2)no1.COc1ccc(C(=O)NN)cc1>>COc1ccc(-c2nnc3n2CCN(C(=O)OC(C)(C)C)C3c2nc(-c3cccc(Cl)c3)no2)cc1,,CCOC(C)=O,CO,,,test
US05846982,N#Cc1ccc2[nH]ccc2c1.O=C1CCN(Cc2ccccc2)CC1>>N#Cc1ccc2[nH]cc(C3=CCN(Cc4ccccc4)CC3)c2c1,,CO,,[K+].[OH-],,test
US20050209213A1,CN1CCC(=O)CC1.Nc1ccc(C=O)c(N)c1>>CN1CCc2nc3cc(N)ccc3cc2C1,,CCO,,[Na+].[OH-],,test
US05017576,Cc1ccc(C2=Nc3cccc(C(F)(F)F)c3C(=O)C2)cc1.O=C(CCl)N1CCOCC1>>Cc1ccc(-c2cc(OCC(=O)N3CCOCC3)c3c(C(F)(F)F)cccc3n2)cc1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130310254A1,CCOC1=CC(=Nc2ccc(C)cc2)/C(=C\O)CC1.Fc1ccc(S)c(F)c1>>CCOC1=CC(=Nc2ccc(C)cc2)C(=CSc2ccc(F)cc2F)CC1,,C1CCOC1,O,CCN(CC)CC,CS(=O)(=O)Cl,test
US20060052595A1,CC(C)(C)C(=O)N1CCC(CCO)(c2ccccc2)OC1>>CC(C)(C)C(=O)N1CCC(CC=O)(c2ccccc2)OC1,,ClCCl,,CCN(C(C)C)C(C)C,CS(C)=O,test
US20070105820A1,CCCCCN1C(=O)C(O)(c2cc3c(cc2O)OCO3)c2c(Br)cccc21>>CCCCCN1C(=O)C(c2cc3c(cc2O)OCO3)c2c(Br)cccc21,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20080161328A1,Cc1nc2cccc(CN)c2c(=O)n1C1CCC(=O)NC1=O.O=C(O)Cc1ccc(F)cc1>>Cc1nc2cccc(CNC(=O)Cc3ccc(F)cc3)c2c(=O)n1C1CCC(=O)NC1=O,,CN(C)C=O,,Cl,O=C(n1ccnc1)n1ccnc1,test
US04593039,COc1cc(N=C=S)cc(OC)c1.NCCN>>COc1cc(NC(=S)NCCN)cc(OC)c1,,CCOCC,,O,,test
US06759546B1,Cc1cc(=O)oc2c(C(C)C)cc(C(C)C)cc12>>CC(=CCO)c1cc(C(C)C)cc(C(C)C)c1O,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20050227959A1,CI.COc1cc(CCNC(=O)OC(C)(C)C)ccc1F>>COc1cc(CCN(C)C(=O)OC(C)(C)C)ccc1F,,CN(C)C=O,,O,[H-].[Na+],test
US20100016350A1,CC(C)(C)OC(=O)N1CCC(C(=O)c2ccc(Br)cn2)C1>>O=C(c1ccc(Br)cn1)C1CCNC1,,C1COCCO1,Cl,,,test
US20100029710A1,CCc1nc2c(C)cc(CO)nc2n1[C@H]1CCc2cc(Br)ccc21.CI>>CCc1nc2c(C)cc(COC)nc2n1[C@H]1CCc2cc(Br)ccc21,,C1CCOC1,,[H-].[Na+],,test
US20100010015A1,N#Cc1ccc2c(c1)C(=O)NC21CCCn2cncc21>>N#Cc1ccc2c(c1)CNC21CCCn2cncc21,,C1CCOC1,,B,,test
US20080227769A1,O=C1CC2CCC(CN1)N2Cc1ccccc1>>c1ccc(CN2C3CCNCC2CC3)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04221919,CC(C)c1ccc(CCl)cc1.COC(=O)Cc1ccc(O)c(Cl)c1>>CC(C)c1ccc(COc2ccc(CC(=O)O)cc2Cl)cc1,,CO,O,,,test
US20140296311A1,COc1cc(-c2noc3c2CCCC3O)ccc1-n1cnc(C)c1.Fc1cc(F)cc(CBr)c1>>COc1cc(-c2noc3c2CCCC3OCc2cc(F)cc(F)c2)ccc1-n1cnc(C)c1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20130072467A1,C#CCNC1=NC(=O)S/C1=C\C1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1.Cl>>C#CCNC1=NC(=O)S/C1=C\C1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1.Cl,,CCO,,,,test
US20090318500A1,CC(C)(C)OC(=O)N1CCC(N)CC1.O=C(O)c1n[nH]cc1NC(=O)c1c(Cl)cccc1Cl>>O=C(NC1CCNCC1)c1n[nH]cc1NC(=O)c1c(Cl)cccc1Cl,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20100029611A1,CC(C)(C)OC(=O)N[C@@H]1CC(=O)OC1=O.Nc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1>>CC(C)(C)OC(=O)N[C@H](CC(=O)O)C(=O)Nc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1,,c1ccccc1,,CC(=O)O,,test
US04788206,COc1ccc(/C(=C\C=C\C(=O)Oc2ccc([N+](=O)[O-])cc2)c2ccccc2OC)cc1.NCCCCc1cccnc1>>COc1ccc(/C(=C\C=C\C(=O)NCCCCc2cccnc2)c2ccccc2OC)cc1,,C1CCOC1,,,,test
US20150322043A1,CC(C)(C)OC(=O)NCCN.O=C(O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1>>NCCNC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1,,C1COCCO1,ClCCl,Cl,,test
US04572912,CCOC(=O)C(Cl)Cc1ccc(OCC2(C)CCc3c(C)c(OC(C)=O)c(C)c(C)c3O2)cc1>>Cc1c(C)c2c(c(C)c1O)CCC(C)(COc1ccc(CC(Cl)C(=O)O)cc1)O2,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20030114712A1,CC(C)=O.OCC1CCCCC1CO>>O=C1OC[C@@H]2CCCC[C@H]12,[Pt],CC(C)=O,,,,test
US20050065191A1,CCOC(=O)NC1CCC=C(C#Cc2ccccc2)C1.CN(C)C=O>>CCOC(=O)N(C)C1CCC=C(C#Cc2ccccc2)C1,,C1CCOC1,,[H-].[Na+],,test
US05444082,CC(=O)SC1CCC2(CCC(CCc3ccoc3)CC2)CC1>>SC1CCC2(CC1)CCC(CCc1ccoc1)CC2,,C1CCOC1,CO,N,[H][H],test
US04105695,CCC(=Cc1c(OC)sc(OC)c1C)[N+](=O)[O-]>>CCC(N)Cc1c(OC)sc(OC)c1C,,C1CCOC1,CCOCC,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05977105,OB(O)c1cccc(OCc2ccccc2)c1.O[C@H](CCc1cccnc1)COc1ccc(Br)cc1>>O[C@H](CCc1cccnc1)COc1ccc(-c2cccc(OCc3ccccc3)c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20160016905A1,Cc1cc[n+](C)cc1.O=Cc1ccc(N2CCOCC2)cc1.[I-]>>C[n+]1ccc(C=Cc2ccc(N3CCOCC3)cc2)cc1.[I-],,CO,,C1CCNCC1,,test
US20160137648A1,CC(C)(C)OCC(C(=O)O)N(CCC#N)C(=O)OC(C)(C)C.CI>>COC(=O)C(COC(C)(C)C)N(CCC#N)C(=O)OC(C)(C)C,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100331306A1,CC(c1nc2ccc(F)cc2c(S(=O)CCO)c1-c1ccccc1)N1C(=O)c2ccccc2C1=O>>CC(N)c1nc2ccc(F)cc2c(S(=O)CCO)c1-c1ccccc1,,CCO,,NN,,test
US20060292079A1,O=C(COc1ccc(CC(CN(CCNC(=O)OCc2ccccc2)CCNC(=O)OCc2ccccc2)NC(=O)OCc2ccccc2)cc1)OCc1ccccc1>>NCCN(CCN)CC(N)Cc1ccc(OCC(=O)O)cc1,[Pd],CC(C)O,,O,,test
US20100331293A1,Cc1c(-c2ccccc2F)nc2ccc(Cl)cc2c1Cl.Nc1cc(N2CCOCC2)ccc1N1CCOCC1>>Cc1c(-c2ccccc2F)nc2ccc(Cl)cc2c1Nc1cc(N2CCOCC2)ccc1N1CCOCC1,,CO,,C1COCCO1,Cl,test
US20110183998A1,CC(CO)NC(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CC(COS(C)(=O)=O)NC(=O)OC(C)(C)C,CN(C)c1ccncc1,C1CCOC1,CCOC(C)=O,CCN(CC)CC,O=C([O-])O.[Na+],test
US04377591,C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(CSCCNC(=O)OCc3ccc([N+](=O)[O-])cc3)C[C@H]12.O=C(OO)c1cccc(Cl)c1>>C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(CS(=O)CCNC(=O)OCc3ccc([N+](=O)[O-])cc3)C[C@H]12,,CS(C)=O,ClCCl,,,test
US20160168100A1,O=C(O)CC(=O)O.O=Cc1ccncc1>>O=C(O)/C=C/c1ccncc1,,O,c1ccncc1,C1CCNCC1,Cl,test
US20030166644A1,CN(C(=O)Oc1ccc(NC(=O)CC(C)(C)C(=O)O)cn1)c1ccccc1>>CN(C(=O)Oc1ccc(N2C(=O)CC(C)(C)C2=O)cn1)c1ccccc1,,ClCCl,,O=S(Cl)Cl,c1ccncc1,test
US05932601,COc1cc(C=CC=O)ccc1OCc1coc(-c2ccccc2)n1.O=C1COC(=O)N1>>COc1cc(C=CC=C2OC(=O)NC2=O)ccc1OCc1coc(-c2ccccc2)n1,,CC(=O)O,,C1CCNCC1,,test
US20150344446A1,CCNC(=O)N(Cc1ccc(C(C)(C)C)cc1)NC(=O)CCC(F)(F)c1cccc(Br)c1>>CCn1c(CCC(F)(F)c2cccc(Br)c2)nn(Cc2ccc(C(C)(C)C)cc2)c1=O,,CCOC(C)=O,Cl,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US20110183938A1,CC(C)(C)OC(=O)N[C@H]1CCN(c2ccnc3c2c2cc(C#N)ncc2n3COCC[Si](C)(C)C)C1.CCI>>CCN(C(=O)OC(C)(C)C)[C@H]1CCN(c2ccnc3c2c2cc(C#N)ncc2n3COCC[Si](C)(C)C)C1,,C1CCOC1,,[H-].[Na+],,test
US20120184553A1,N#Cc1ccc(OCc2ccccc2)c(C(=O)O)c1.Nc1cccnc1>>N#Cc1ccc(OCc2ccccc2)c(C(=O)Nc2cccnc2)c1,,CN(C)C=O,O,ClCCCl,On1nnc2ccccc21,test
US20150191463A1,CN(C)C=O.Cc1c(Br)cccc1C(=O)O>>Cc1c(Br)cccc1C#N,,O=S(Cl)Cl,,,,test
US20130231324A1,COc1cnc(-n2cnc(C)n2)c2[nH]cc(C(=O)C(=O)O)c12.c1ccc(-n2nnnc2N2CC3(CNC3)C2)cc1>>COc1cnc(-n2cnc(C)n2)c2[nH]cc(C(=O)C(=O)N3CC4(C3)CN(c3nnnn3-c3ccccc3)C4)c12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20150119379A1,OC(CCl)CNC(c1ccccc1)c1ccccc1>>OC1CN(C(c2ccccc2)c2ccccc2)C1,,CCO,,CCN(C(C)C)C(C)C,,test
US20040082611A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COCCNCCC1CN(Cc2ccccc2)CCN1Cc1ccccc1>>COCCN(CCC1CN(Cc2ccccc2)CCN1Cc1ccccc1)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20130085142A1,CCOC(=O)C1CNCCN1.FC(F)(F)c1cccc(Br)n1>>CCOC(=O)C1CN(c2cccc(C(F)(F)F)n2)CCN1,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US20110295017A1,Brc1c2ccccc2c(-c2ccccc2)c2ccccc12.CCOB(OCC)OCC>>OB(O)c1c2ccccc2c(-c2ccccc2)c2ccccc12,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US20090209553A1,CS(=O)(=O)Cl.OCC1(Nc2ccc3[nH]ncc3c2)CCC1>>CS(=O)(=O)OCC1(Nc2ccc3[nH]ncc3c2)CCC1,,ClCCl,,CCN(CC)CC,,test
US20060111375A1,CC[Mg]Br.COc1cc2nccc(Oc3ccc(C(C)(C)C)cc3C=O)c2cc1OC>>CCC(O)c1cc(C(C)(C)C)ccc1Oc1ccnc2cc(OC)c(OC)cc12,,C1CCOC1,,O,,test
US20140024649A1,CC(C)(C)OC(=O)CC(=O)OC(C)(C)C.COC(=O)c1ccc(-c2nc(CCl)c(C)o2)cc1>>COC(=O)c1ccc(-c2nc(CC(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(C)o2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150094297A1,Cc1sc(C2CCOCC2)nc1CO[Si](C)(C)C(C)(C)C>>Cc1sc(C2CCOCC2)nc1CO,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06127361,COc1ccc(CCN2CCC[C@H](Cl)C2)cc1OC.c1ccc2c(c1)COc1ccccc1N2>>COc1ccc(CCN2CCC[C@@H]2CN2c3ccccc3COc3ccccc32)cc1OC,,CS(C)=O,,[H-].[Na+],,test
US20120134934A1,CCOC(=O)NC(C(=O)O[C@H]1CN2CCC1CC2)c1ccccc1.O=C(CBr)c1ccccc1>>CCOC(=O)NC(C(=O)O[C@H]1C[N+]2(CC(=O)c3ccccc3)CCC1CC2)c1ccccc1.[Br-],,CC#N,CCOC(C)=O,,,test
US04665189,BrCCCCCCCCOC1CCCCO1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>[Br-].c1ccc([P+](CCCCCCCCOC2CCCCO2)(c2ccccc2)c2ccccc2)cc1,,CC#N,,,,test
US20090209607A1,Cn1ncc(Br)c1-c1sc(C(=O)O)cc1Br.N[C@@H](Cc1ccccc1C(F)(F)F)CN1C(=O)c2ccccc2C1=O>>Cn1ncc(Br)c1-c1sc(C(=O)N[C@@H](Cc2ccccc2C(F)(F)F)CN2C(=O)c3ccccc3C2=O)cc1Br,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US04435585,CC(C=O)=Cc1ccc(C(C)(C)C)cc1>>CC(C=O)Cc1ccc(C(C)(C)C)cc1,[Pd],O,,[H][H],,test
US20020103161A1,CC(C)I.Clc1ncnc2[nH]cc(I)c12>>CC(C)n1cc(I)c2c(Cl)ncnc21,,CN(C)C=O,,O,[H-].[Na+],test
US04939282,CCCCCC.COC(=O)C1CCC2(C3(C)OCCO3)CC1C(=O)O2.COC1C(=C=O)CC2(C3(C)OCCO3)CC1C(=O)O2>>COc1cc(C(=O)C2CCC3(C4(C)OCCO4)CC2C(=O)O3)c(OC)c2c(OC)cccc12,,C1CCOC1,,[Li]CCCC,,test
US20130158025A1,CCOC(=O)CC(=O)c1cccc(OC)c1.Cc1ccc(-c2c(C)n[nH]c2N)cc1>>COc1cccc(-c2cc(=O)[nH]c3c(-c4ccc(C)cc4)c(C)nn23)c1,,c1ccncc1,,,,test
US20050090533A1,Cc1cc(F)ccc1-c1cc(N2CCC(=O)CC2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.OCCS>>Cc1cc(F)ccc1-c1cc(N2CCC3(CC2)OCCS3)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,ClCCl,,CCOCC,FB(F)F,test
US20080146637A1,CC=C(O[Si](C)(C)C(C)(C)C)c1ccccc1-c1ccc2[nH]c(COc3ccc(C(F)(F)F)cc3)nc2c1.O=C(OO)c1cccc(Cl)c1>>CC1OC1(O[Si](C)(C)C(C)(C)C)c1ccccc1-c1ccc2[nH]c(COc3ccc(C(F)(F)F)cc3)nc2c1,,ClCCl,,,,test
US07964733B2,CC[C@H](NC(=O)c1c(C)c(-c2ccccc2)nc2ccccc12)c1ccccc1.O=C1CCC(=O)N1Br>>CC[C@H](NC(=O)c1c(CBr)c(-c2ccccc2)nc2ccccc12)c1ccccc1,,ClC(Cl)(Cl)Cl,,,,test
US03994961,CN(C)CCC1Cc2ccccc2C(=O)c2ccccc21.C[Si](C)(C)CCl>>CN(C)CCC1Cc2ccccc2C(O)(C[Si](C)(C)C)c2ccccc21,,CCOCC,,[Mg],[Cl-].[NH4+],test
US20120040954A1,CC(C)C(=O)Cl.COc1cc(OC)c2c(=O)[nH]c(-c3ccc(N4CCNCC4)cc3)nc2c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(N4CCN(C(=O)C(C)C)CC4)cc3)nc2c1,,ClCCl,,CCN(CC)CC,,test
US20160200695A1,COC(=O)c1ccc(C(=O)[O-])cc1.Nc1nc2ccc(O)cc2s1>>COC(=O)c1ccc(C(=O)Nc2nc3ccc(O)cc3s2)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140057303A1,Cc1cc(C#N)c(Nc2ccc(C#N)cc2[N+](=O)[O-])s1.Cl>>Cc1cc2c(s1)Nc1ccc(C#N)cc1N=C2N.Cl,,CCO,Cl,Cl[Sn](Cl)(Cl)Cl,,test
US04539152,C=CC[C@@H]1[C@@H](N)C(=O)N1C(C(=O)OC)=C(C)C.O=C(Cl)OCc1ccccc1>>C=CC[C@@H]1[C@@H](NC(=O)OCc2ccccc2)C(=O)N1C(C(=O)OC)=C(C)C,,CCOC(C)=O,ClCCl,Cc1cccc(C)n1,,test
US06528543B1,C=CCN=C=O.NC(=O)[C@H](CC1CCCC1)c1ccc(Cl)c(Cl)c1>>C=CCNC(=O)NC(=O)[C@H](CC1CCCC1)c1ccc(Cl)c(Cl)c1,,Cc1ccccc1,,,,test
US20090137595A1,Cn1cccc1C(=O)O.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1>>Cn1cccc1C(=O)Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1,,C1CCOC1,CC(=O)N(C)C,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20120329782A1,CC(C)(C)c1nc(-c2ccc(F)cc2N)c(-c2cccnc2F)[nH]1>>CC(C)(C)c1nc2c([nH]1)-c1cccnc1Nc1cc(F)ccc1-2,,CCO,,,,test
US20160145245A1,CN(C(=O)Cc1ccc(Cl)c(Cl)c1)[C@H](CN1CC[C@@H](O)C1)c1cccc(N)c1.N#Cc1ccc(S(=O)(=O)Cl)cc1>>CN(C(=O)Cc1ccc(Cl)c(Cl)c1)[C@H](CN1CC[C@@H](O)C1)c1cccc(NS(=O)(=O)c2ccc(C#N)cc2)c1,,ClCCl,,c1ccncc1,,test
US20120165347A1,CC(=O)C(N)=S.CC(C)(C)S(=O)N=C1CC(C2CCCOC2)Oc2ccc(Br)cc21>>CC1=NC2(CC(C3CCCOC3)Oc3ccc(Br)cc32)NC1=S,,CC#N,,,,test
US03932416,NC1CCCCC1.O=C(Nc1nnn[nH]1)c1cc(Cl)c2ccccc2n1>>Cl.O=C(Nc1nnn[nH]1)c1cc(NC2CCCCC2)c2ccccc2n1,,O,,,,test
US20080064872A1,CCOC(=O)CC(C)=O.CS(=O)(=O)c1nnc(-c2ccccc2)c(-c2ccccc2)n1>>CCOC(=O)Cc1nnc(-c2ccccc2)c(-c2ccccc2)n1,,C1CCOC1,,[H-].[Na+],,test
US05905076,N[C@@H]1C(=O)N2CCO[C@H]12.O=C(N[C@@H](Cc1ccccc1)C(=O)O)OCc1ccccc1>>NC1CO[C@@H]2[C@@H](C(=O)[C@H](Cc3ccccc3)NC(=O)OCc3ccccc3)C(=O)N12,,CCOC(C)=O,ClCCl,CCN(CC)CC,CCOC(=O)Cl,test
US20040180934A1,BrCc1ccccc1.COC(=O)CC1CCn2c1cc1c(C(C)C)cc(O)cc12>>COC(=O)CC1CCn2c1cc1c(C(C)C)cc(OCc3ccccc3)cc12,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06005103,C1CCNCC1.CC(=O)O.CCO.CCOC(=O)c1ccc(-c2cc(O)cc(=O)o2)cc1.SC1CCCC1>>CCOC(=O)c1ccc(-c2cc(O)c(C(CC(C)C)SC3CCCC3)c(=O)o2)cc1,,CC(=O)O,,,,test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCC1CCN(C)CC1.Cc1cc2c(F)c(O)ccc2[nH]1>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCC1CCN(C)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20010027196A1,CN(C)CCN.CS(=O)(=O)c1nc(N)nc(-c2ccco2)c1C#N>>CN(C)CCNc1nc(N)nc(-c2ccco2)c1C#N,,COCCOC,,,,test
US20070072879A1,N#Cc1cnc(N)nc1.NO>>N=C(NO)c1cnc(N)nc1,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20150203483A1,CNC(=O)N1N=C(c2ccc(Br)cc2)c2cc(O)c(OC)cc2CC1C.CNC(=O)N1N=C(c2ccc(Br)cc2)c2cc(OC)c(OC)cc2CC1C>>CNC(=O)N1N=C(c2ccc(Br)cc2)c2cc(OC)c(O)cc2CC1C,,ClCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20110315965A1,Brc1ccc2ccc(Br)cc2c1.OB(O)c1cc2ccccc2c2ccccc12>>Brc1ccc2ccc(-c3cc4ccccc4c4ccccc34)cc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20120122843A1,COc1nc(N)ccc1Br.Cn1cc(B2OC(C)(C)C(C)(C)O2)ccc1=O>>COc1nc(N)ccc1-c1ccc(=O)n(C)c1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20140275152A1,O=S(Cl)Cl.OCc1cccnc1-c1ccnn1C1CCCC1>>Cl.ClCc1cccnc1-c1ccnn1C1CCCC1,,ClCCl,,,,test
US20070244095A1,Cc1cc2c(cc1C(F)(F)F)N(C(=O)OC(C)(C)C)CCC[C@@H]2N(C#N)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1.[N-]=[N+]=[N-]>>Cc1cc2c(cc1C(F)(F)F)N(C(=O)OC(C)(C)C)CCC[C@@H]2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nn[nH]n1,,CCOC(C)=O,Cc1ccccc1,CCN(CC)CC,Cl,test
US20100179139A1,CC(C)(C)c1cc2c(-c3ccc(S(=O)(=O)N4CCCC4)nc3)ccnc2[nH]1.O=S(=O)(O)O>>CC(C)(C)c1cc2c(-c3ccc(S(=O)(=O)N4CCCC4)nc3)ccnc2[nH]1.O=S(=O)(O)O,,CO,,,,test
US04943580,BrCc1ccccc1.CCOCCn1c(NC2CCN(C(=O)OCC)CC2)nc2cccnc21>>CCOCCn1c(N(Cc2ccccc2)C2CCN(C(=O)OCC)CC2)nc2cccnc21,,O,,CN(C)C=O,[H-].[Na+],test
US20030105161A1,Cl.Cn1ccnc1[C@@H](CCCNC(=O)OC(C)(C)C)Oc1cc(Cl)c(F)cc1C#N>>Cl.Cn1ccnc1[C@@H](CCCN)Oc1cc(Cl)c(F)cc1C#N,,C1COCCO1,Cl,,,test
US20140024650A1,N#Cc1ccc(Br)nc1.OB(O)c1ccc(O)cc1>>N#Cc1ccc(-c2ccc(O)cc2)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20050004162A1,CI.Clc1ccc2scc(CCN3CC=C(c4c[nH]c5ccccc45)CC3)c2c1>>Cn1cc(C2=CCN(CCc3csc4ccc(Cl)cc34)CC2)c2ccccc21,,C1CCOC1,,CCCCCC,,test
US20120208819A1,CC(C)(C)OC(=O)NCc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Nc1n[nH]c2ncc(Br)cc12>>CC(C)(C)OC(=O)NCc1ccc(-c2cnc3[nH]nc(N)c3c2)cc1,,C1COCCO1,O,O=C([O-])O.[Na+],,test
US20160039772A1,Cn1c(=O)n(CCCO[Si](C)(C)C(C)(C)C)c(=O)c2c(C(O)c3ccccc3)c(OC(F)(F)F)ccc21.O=C(O)C(F)(F)F>>Cn1c(=O)n(CCCOC(=O)C(F)(F)F)c(=O)c2c(Cc3ccccc3)c(OC(F)(F)F)ccc21,,CCOC(C)=O,O,CC[SiH](CC)CC,,test
US05808062,CCC(=O)c1ccc(O)cc1.COC(=O)CBr>>CC(=O)OOc1ccc(C(C)=O)cc1C,,O,,CC(C)=O,,test
US20100130464A1,Cc1c(-c2ccc(CC#N)cc2)c(C(F)(F)F)nn1C1CCCCO1>>Cc1[nH]nc(C(F)(F)F)c1-c1ccc(CC#N)cc1,,CCOC(C)=O,,Cl,,test
US20090274655A1,Nc1ccc(I)cc1.O=C(O)c1cscn1>>O=C(Nc1ccc(I)cc1)c1cscn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05760235,O=C(OC1CCCCO1)[C@@H]1CCCN1C(=O)[C@H](O)Cc1ccccc1.[NH3+]C1CCCCC1>>O=C(OC1CCCCO1)[C@@H]1CCCN1C(=O)[C@H](O)Cc1ccccc1.[NH3+]C1CCCCC1,,CCOCC,,,,test
US20150011548A1,CCN1CCNCC1.O=S(=O)(Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(Br)ccc32)c1)C1CC1>>CCN1CCN(c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-c3ccc(F)cc3F)c2)CC1,[Cu]I,CS(C)=O,,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US20070161673A1,Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(N)n[nH]c2n1.O=S(=O)(Cl)c1ccc(F)cc1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(NS(=O)(=O)c3ccc(F)cc3)n[nH]c2n1,,c1ccncc1,,,,test
US20140378459A1,CC(C)(C)OC(=O)CN(Cc1cccc([N+](=O)[O-])c1)C(=O)C(F)(F)F>>CC(C)(C)OC(=O)CN(Cc1cccc(N)c1)C(=O)C(F)(F)F,[Fe],CCO,,O,[Cl-].[NH4+],test
US20090111797A1,CC(C)(C)OC(=O)N1CCC(N2CCN(C(=O)[C@@H](Cc3ccc(Cl)c(Cl)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1>>O=C(O[C@H](Cc1ccc(Cl)c(Cl)c1)C(=O)N1CCN(C2CCNCC2)CC1)N1CCC(N2CCc3ccccc3NC2=O)CC1,,Cl,,,,test
US20090062293A1,CC(C)(C)CCC(=O)N1CCN(c2nccc(C(N)=NO)n2)CC1.CCOC(C)=O>>Cc1nc(-c2ccnc(N3CCN(C(=O)CCC(C)(C)C)CC3)n2)no1,,CCOC(C)=O,,C1CCOC1,[Na+].[OH-],test
US20120040972A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CCN2CCC(c3noc4ccc(F)cc34)CC2)CC1.O=C(O)C(F)(F)F>>N[C@@H]1CC[C@@H](CCN2CCC(c3noc4ccc(F)cc34)CC2)CC1.O=C(O)C(F)(F)F,,ClCCl,,O=C([O-])O.[Na+],,test
US20040132727A1,COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.COc1ccc(C(C)O)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc(C(C)OC(=O)Nc2ccc(Oc3ncnc4cc(OC)c(OC)cc34)cc2)cc1,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20100204196A1,COc1cc(N2CCN(C(C)C)CC2)ccc1Nc1nc(Nc2cccc(F)c2C(N)=O)c2ccn(S(=O)(=O)c3ccc(C)cc3)c2n1>>COc1cc(N2CCN(C(C)C)CC2)ccc1Nc1nc(Nc2cccc(F)c2C(N)=O)c2ccnc-2[nH]1,,C1CCOC1,CO,O=C([O-])[O-].[K+].[K+],,test
US04018824,CC(C)(C)N1CC(OCc2ccccc2)C1>>CC(C)(C)N1CC(O)C1,[Ni],CCO,,,,test
US20050288290A1,Cc1c(OC(=O)C(C)(C)C)cn2ncnc(Oc3ccc([N+](=O)[O-])cc3F)c12>>Cc1c(O)cn2ncnc(Oc3ccc([N+](=O)[O-])cc3F)c12,,CCO,,Cl,[Na+].[OH-],test
US20150361059A1,COC(=O)c1ccc(CNC(=O)c2cccc3c2OC[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)N3Cc2c(OC)ccc3cc(Br)ccc23)cc1>>CN[C@@H](C)C(=O)N[C@H]1COc2c(C(=O)NCc3ccc(C(=O)OC)cc3)cccc2N(Cc2c(OC)ccc3cc(Br)ccc23)C1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140011971A1,CC(C)(C)CC(C)(C)N.O=Cc1ccccn1>>CC(C)(C)CC(C)(C)/N=C/c1ccccn1,,ClCCl,,O,,test
US05589477,COc1ccc(-c2cc(Cl)nc(C)n2)cc1.Cl.OCCN1CCCCC1>>COc1ccc(-c2cc(OCCN3CCCCC3)nc(C)n2)cc1.Cl.Cl,,C1CCOC1,CCO,[H-].[Na+],,test
US20060014701A1,Cl.[N-]=[N+]=NC[C@H](O)CN1C(=O)c2ccccc2C1=O>>Cl.NC[C@H](O)CN1C(=O)c2ccccc2C1=O,[Pd],CCO,,[H][H],,test
US20130090340A1,CC(C)(C)NC(=O)N1CCn2c(Cl)c(-c3ccccc3)c(C(N)=O)c2C1>>CC(C)(C)NC(=O)N1CCn2cc(-c3ccccc3)c(C(N)=O)c2C1,[Pd],CO,,O=C[O-].[NH4+],,test
US20050267149A1,CCOc1ccccc1CCNC(=O)CCc1ccc(OCc2ccccc2C(=O)OC)cc1>>CCOc1ccccc1CCNC(=O)CCc1ccc(OCc2ccccc2C(=O)O)cc1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20060111445A1,CCCCCC(=O)c1cc(CCC(=O)OCC)ccc1OC>>CCCCCC(O)c1cc(CCC(=O)OCC)ccc1OC,,CCO,,[BH4-].[Na+],,test
US04963180,C=CCOC(=O)c1cccc(C)c1O.O=C=NS(=O)(=O)Cl>>C=CCOC(=O)c1cccc(C)c1OS(=O)(=O)N=C=O,,Cc1ccccc1,,,,test
US04948794,CCO.CCOC(C)=O.Nc1cc(F)ccc1NC(c1ccccc1)c1ccccc1>>O=c1[nH]c2cc(F)ccc2n(C(c2ccccc2)c2ccccc2)c1=O,[Pd],O,,CCN(CC)CC,Cl,test
US20140179667A1,CCOC(CN)OCC.COc1cccc(C(=O)O)c1[N+](=O)[O-]>>CCOC(CNC(=O)c1cccc(OC)c1[N+](=O)[O-])OCC,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20120178744A1,CCOC(=O)C1CCC(Cc2cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n3ncc(-c4ccc(Cl)nc4)c3n2)CC1.OB(O)c1ccccc1>>CCOC(=O)C1CCC(Cc2cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n3ncc(-c4ccc(-c5ccccc5)nc4)c3n2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US07452893B2,Cc1ccc(C(F)(F)CN[C@H]2CC[C@H](N)C2)cc1.Clc1ncnc2nn(C3CCCCO3)cc12>>Cc1ccc(C(F)(F)CN[C@H]2CC[C@H](Nc3ncnc4nn(C5CCCCO5)cc34)C2)cc1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20150266878A1,CS(=O)(=O)Cl.NCC(Nc1cncc(Br)c1)c1ccccc1>>CS(=O)(=O)NCC(Nc1cncc(Br)c1)c1ccccc1,,ClCCl,O,CCN(C(C)C)C(C)C,,test
US20090028925A1,BrC(Br)(Br)Br.COCOc1ccc(Cc2c(C)cc(CO)c(C)c2C)cc1C(C)C>>COCOc1ccc(Cc2c(C)cc(CBr)c(C)c2C)cc1C(C)C,,CCOCC,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20130190325A1,CCOC(=O)CNc1cc(CS(=O)(=O)/C=C/c2c(OC)cc(OC)cc2OC)cnc1OC>>COc1cc(OC)c(/C=C/S(=O)(=O)Cc2cnc(OC)c(NCC(=O)O)c2)c(OC)c1,,O,,Cl,[Na+].[OH-],test
US20130217668A1,COC(=O)[C@H]1CC[C@@H](n2/c(=N/C(=O)c3ccccc3)[nH]c3cnc(OCCN4CCCCC4)cc32)CC1>>O=C(/N=c1\[nH]c2cnc(OCCN3CCCCC3)cc2n1[C@@H]1CC[C@H](C(=O)O)CC1)c1ccccc1,,CO,,[Na+].[OH-],,test
US20160072082A1,CC(C)=Cc1cnc2c3ccccc3c3c(-c4ccccc4)cccc3n12>>CC1(C)Cc2cnc3c4ccccc4c4c(-c5ccccc5)ccc1c4n23,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20060052426A1,CCC[C@H](NC(=O)OC(C)(C)C)C(=O)Nc1ncc(-c2ccccc2COc2ccccc2)s1.Cl>>CCC[C@H](N)C(=O)Nc1ncc(-c2ccccc2COc2ccccc2)s1.Cl,,CCOC(C)=O,,,,test
US20150099719A1,COC(=O)[C@@H]1CCCC[C@H]1C(=O)C(NC(=O)c1ccc(F)cc1)c1ccc(Br)cc1>>COC(=O)[C@@H]1CCCC[C@H]1c1oc(-c2ccc(F)cc2)nc1-c1ccc(Br)cc1,,O=P(Cl)(Cl)Cl,,,,test
US05104888,CC(=O)Oc1c(C)c(C)c2c(c1C)C(=O)CC(O)(COc1ccc([N+](=O)[O-])cc1)O2>>CC(=O)Oc1c(C)c(C)c2c(c1C)C(=O)CC(O)(COc1ccc(N)cc1)O2,[Pd],CCO,,C1CCOC1,,test
US20110212918A1,Nc1cc(Cl)c(I)cn1.SCc1ccccc1>>Nc1cc(Cl)c(SCc2ccccc2)cn1,,CO,,[Na],,test
US20160214978A1,FC(F)(F)c1ccc(Nc2nc(Cl)cc(Cl)n2)cc1.OB(O)c1ccnc2ccccc12>>FC(F)(F)c1ccc(Nc2nc(Cl)cc(-c3ccnc4ccccc34)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20150166512A1,CCOC(CN)OCC.Cc1ccc(Cl)cc1C(=O)CC#N>>CCOC(CNC(=CC#N)c1cc(Cl)ccc1C)OCC,,Cc1ccccc1,,,,test
US04243678,CC(=O)Cl.CCOC(=O)CCCNC(c1ccccc1)c1ccccc1>>CCOC(=O)CCCN(C(C)=O)C(c1ccccc1)c1ccccc1,,c1ccccc1,,CCN(C(C)C)C(C)C,CS(C)=O,test
US20130116263A1,Cc1nccnc1-c1ccc(-c2cc3c(C(C)(C)C)nc(S(C)=O)nc3n(Cc3cccnc3)c2=O)c(Cl)c1.N[C@@H]1CCOC1>>Cc1nccnc1-c1ccc(-c2cc3cnc(N[C@@H]4CCOC4)nc3n(Cc3cccnc3)c2=O)c(Cl)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US20090270374A1,COc1ccc2ccc(=O)n(CCN3C[C@H](CN)[C@H](O)C3)c2c1.ClCCl.O=Cc1ccc2c(n1)NC(=O)CO2>>COc1ccc2ccc(=O)n(CCN3C[C@H](CNCc4ccc5c(n4)NC(=O)CO5)[C@H](O)C3)c2c1.Cl,,CO,,O=C([O-])[O-].[Na+].[Na+],,test
US20140349972A1,CCOP(=O)(OCC)c1ccc(C(NC(=O)c2cnc(-c3ccccn3)nc2O)c2ccc(OC)cc2)cc1>>COc1ccc(C(NC(=O)c2cnc(-c3ccccn3)nc2O)c2ccc(P(=O)(O)O)cc2)cc1,,ClCCl,,C[Si](C)(C)Br,,test
US20110021522A1,COc1ccc(OC)c(B(O)O)c1.Nc1cccc(Br)c1>>COc1ccc(OC)c(-c2cccc(N)c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20100256181A1,N#Cc1cc(Cl)cc(Oc2c(C(F)(F)F)cc[nH]c2=O)c1.NS(=O)(=O)c1ccc(NC(=O)CBr)c(Cl)c1>>N#Cc1cc(Cl)cc(Oc2c(C(F)(F)F)ccn(CC(=O)Nc3ccc(S(N)(=O)=O)cc3Cl)c2=O)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20130096113A1,COCCOc1ccn2c(Cc3ccc4nc(N[C@@H]5CCCC[C@H]5O)sc4c3)cnc2c1>>OCCOc1ccn2c(Cc3ccc4nc(N[C@@H]5CCCC[C@H]5O)sc4c3)cnc2c1,,ClCCl,,BrB(Br)Br,,test
US05057630,CO.O=C([O-])C[C@@H]1C=C[C@H](C[N+](=O)[O-])C1>>O=[N+]([O-])C[C@@H]1C=C[C@H](O)C1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20130143863A1,O=C1c2ccc(Cl)cc2CCN1c1cncc(CCl)c1.c1c[nH]cn1>>O=C1c2ccc(Cl)cc2CCN1c1cncc(Cn2ccnc2)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20120196848A1,C/C=C\c1csc2c1O[C@@H](C)CN(C(=O)OC(C)(C)C)C2>>CCCc1csc2c1O[C@@H](C)CN(C(=O)OC(C)(C)C)C2,[Pd],C1CCOC1,CO,,,test
US20140142081A1,COC(=O)OC.COc1cccc(C)n1>>COC(=O)Cc1cccc(OC)n1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20080058328A1,Nc1ccccc1[C@@H]1CN(C2CC2)Cc2c(Cl)cc(Cl)cc21.O=C(Cl)OCCCl>>O=C(Nc1ccccc1[C@@H]1CN(C2CC2)Cc2c(Cl)cc(Cl)cc21)OCCCl,,C1CCOC1,,,,test
US05143920,CCCC(=O)c1cnc2c(OC)cccc2c1Cl.Nc1ccc(O)c(F)c1>>CCCC(=O)c1cnc2c(OC)cccc2c1Nc1ccc(O)c(F)c1,,C1COCCO1,,,,test
US20110269746A1,C=CS(=O)(=O)N(C)C.O=C(OCc1ccccc1)N1CCC(O)CC1>>CN(C)S(=O)(=O)CCOC1CCN(C(=O)OCc2ccccc2)CC1,,C1CCOC1,,O,[H-].[Na+],test
US20150183804A1,CC(C)(C)OC(=O)Nc1ccc(CCO)cc1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)Nc1ccc(CCBr)cc1,,CCOCC,ClCCl,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04046753,Cc1ccccc1NNC1=NCCS1>>Cc1ccccc1N=NC1=NCCS1,O=[Ag],CCOC(C)=O,,,,test
US20100239496A1,CCN(CC)c1ccc(C(=O)CBr)cc1.Nc1nc2ccccc2[nH]1>>CCN(CC)c1ccc(C(=O)Cn2c(N)nc3ccccc32)cc1,,CO,,,,test
US05075445,CC(=O)OCC(CCn1cnc2c(Cl)nc(N)nc21)COC(C)=O>>Nc1nc2c(ncn2CCC(CO)CO)c(=O)[nH]1,,Cl,,[Na+].[OH-],,test
US20040053942A1,O=C1NC(=O)c2ccccc21.OCc1ccn2nc(-c3ccc(F)cc3)c(-c3ccncc3)c2c1>>O=C1c2ccccc2C(=O)N1Cc1ccn2nc(-c3ccc(F)cc3)c(-c3ccncc3)c2c1,,C1CCOC1,CCOCC,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090099182A1,COC1CCC(C2CCNC2=O)CC1.Clc1cc(Br)cc(Cl)c1CBr>>COC1CCC(C2CCN(Cc3c(Cl)cc(Br)cc3Cl)C2=O)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20130289033A1,O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(I)c1.OB(O)c1ccc(C(F)(F)F)cc1>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(-c2ccc(C(F)(F)F)cc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US05134231,CC(COCc1ccccc1)C(=O)CC(=O)OCc1ccc([N+](=O)[O-])cc1.CO>>COC(=O)CC(=O)C(C)COCc1ccccc1,,CCOC(C)=O,,[BH4-].[Na+],,test
US20120004203A1,CC1=C(C#N)C(c2ccc(C#N)cc2)n2nc(N3C(=O)c4ccccc4C3=O)nc2N1c1cccc(C(F)(F)F)c1.O>>CC1=C(C#N)C(c2ccc(C#N)cc2)n2nc(NC(=O)c3ccccc3C(=O)O)nc2N1c1cccc(C(F)(F)F)c1,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100331295A1,CS(=O)(=O)c1cccc(-c2ccc(/C(O)=C/C(=O)C(F)(F)F)s2)c1.NNc1cc(Cl)ccc1Cl>>CS(=O)(=O)c1cccc(-c2ccc(-c3cc(C(F)(F)F)nn3-c3cc(Cl)ccc3Cl)s2)c1,,CN(C)C=O,,CC(=O)O,Cl,test
US20130143925A1,CCOC(=O)C(F)(F)F.O=C(Nc1ccc(OC(F)(F)F)cc1)NC1CCNCC1>>O=C(Nc1ccc(OC(F)(F)F)cc1)NC1CCN(C(=O)C(F)(F)F)CC1,,C1CCOC1,,,,test
US20140011800A1,CNC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cn1.C[C@H]1[C@H](Nc2c(C(N)=O)cnn3cc(Br)cc23)C[C@@H]2CN(C(=O)C(C)(C)O)C[C@H]12>>CNC(=O)c1ccc(-c2cc3c(N[C@@H]4C[C@@H]5CN(C(=O)C(C)(C)O)C[C@@H]5[C@H]4C)c(C(N)=O)cnn3c2)cn1,,CN(C)C=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140336190A1,NN.O=C(CC(=O)C1CC1)C1CC1>>c1c(C2CC2)n[nH]c1C1CC1,,CCO,,,,test
US06495555B1,CCOP(=O)(CC#N)OCC.Cc1ccc2c(c1)C(=O)CO2>>Cc1ccc2oc(CC#N)cc2c1,,C1CCOC1,,O,[H-].[Na+],test
US20040102437A1,CCOC(=O)C1CCC(=O)CC1.Nc1ccc2[nH]ncc2c1>>CCOC(=O)C1CCC(Nc2ccc3[nH]ncc3c2)CC1,,CO,,O=C([O-])O.[Na+],,test
US04977272,C1CCOC1.C=CCOC(=O)[C@H](C)N.COC(OC)OC.NO.[N-]=C=O.c1ccncc1>>C=CCOC(=O)C(C)NC(=O)Nc1ccc(C=NO)cc1,,CO,,Cl,,test
US20090036492A1,CC#CCBr.COc1cc(O)c2c(c1C(=O)NCc1c(C)cc(O)cc1C)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>CC#CCOc1cc(C)c(CNC(=O)c2c(OC)cc(O)c3c2OC2=CC(O)=C(C(C)=O)C(=O)[C@]23C)c(C)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20110104057A1,COC(=O)CC[C@H](NC(=O)OC(C)(C)C)C(=O)OC.O=[N+]([O-])c1ccc(CBr)cc1[N+](=O)[O-]>>COC(=O)C(Cc1ccc([N+](=O)[O-])c([N+](=O)[O-])c1)CC(NC(=O)OC(C)(C)C)C(=O)OC,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20130237501A1,CNC(=O)c1c(-c2ccc(Cl)cc2)oc2cc(N(c3ccc([N+](=O)[O-])c(C#N)c3)S(C)(=O)=O)c(C3CC3)cc12>>CNC(=O)c1c(-c2ccc(Cl)cc2)oc2cc(N(c3ccc(N)c(C#N)c3)S(C)(=O)=O)c(C3CC3)cc12,,C1CCOC1,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20040224946A1,COC(=O)C1CCN(Cc2ccccc2)C1>>COC(=O)C1CCNC1,[Pd],CO,,O=C[O-].[NH4+],,test
US03962445,Cc1cccc2c(O)cc(=O)[nH]c12.O=[N+]([O-])O>>Cc1cccc2c(O)c([N+](=O)[O-])c(=O)[nH]c12,,CC(=O)O,,,,test
US20110245205A1,Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C3(O)CCN(S(=O)(=O)NC(=O)OC(C)(C)C)CC3)s2)c1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C3(O)CCN(S(N)(=O)=O)CC3)s2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080153828A1,CCC(CC)c1cc(C)nn2c(I)c(C)nc12.Cc1sc2cnccc2c1Br>>CCC(CC)c1cc(C)nn2c(-c3c(C)sc4cnccc34)c(C)nc12,[Zn],C1CCOC1,,,,test
US04731364,C=CCO[C@H]1c2ccc(Cl)cc2S[C@H]1Cn1ccnc1.O=C(OO)c1cccc(Cl)c1>>C=CCO[C@H]1c2ccc(Cl)cc2S(=O)[C@H]1Cn1ccnc1,,ClCCl,,,,test
US20080032967A1,CC(C)(C)Oc1cccc(C(=O)O)c1.Nc1ccc(OCCN2CCOCC2)c2ccccc12>>CC(C)(C)Oc1cccc(C(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090227640A1,COC(=O)c1ccc(CC(CO)CCCCC#N)cc1>>COC(=O)c1ccc(CC(C=O)CCCCC#N)cc1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20160169864A1,CC(Br)Br.COc1cc(C=O)ccc1O>>COc1cc(C=O)ccc1OCCBr,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080287409A1,N=C(NO)c1ccc(OCc2sc(-c3ccc(C(F)(F)F)cc3)nc2CN2CCC(C(F)(F)F)CC2)cc1OC(F)F.O=C(Cl)Oc1ccccc1>>O=c1[nH]c(-c2ccc(OCc3sc(-c4ccc(C(F)(F)F)cc4)nc3CN3CCC(C(F)(F)F)CC3)cc2OC(F)F)no1,,C1CCOC1,,CCN(C(C)C)C(C)C,O,test
US20140275027A1,N#Cc1cnc2[nH]ccc2c1Cl.O=S(=O)(Cl)c1ccccc1>>N#Cc1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1Cl,,C1CCOC1,,CCN(CC)CC,,test
US20130158025A1,CCOCC(=O)OCC.Cc1ccc(CC#N)cc1>>CCOCC(=O)C(C#N)c1ccc(C)cc1,,CCO,,C,C[O-].[Na+],test
US20130274257A1,Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1-c1cccc([N+](=O)[O-])c1>>Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1-c1cccc(N)c1,[Fe],CCO,,CC(=O)O,,test
US20120114765A1,CN.O=C(O)c1cc([N+](=O)[O-])c(Sc2cccc(Cl)c2Cl)s1>>CNC(=O)c1cc([N+](=O)[O-])c(Sc2cccc(Cl)c2Cl)s1,,C1COCCO1,Cc1ccccc1,O=S(Cl)Cl,,test
US20120041030A1,CC(=O)OCCCCCCCCOc1cc[nH]c(=O)c1C.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(=O)OCCCCCCCCOc1cc[nH]c(=S)c1C,,Cc1ccccc1,,,,test
US20090054478A1,Cc1cc(Cl)nc2[nH]nc(O)c12.O=C=NC1CCCc2ccccc21>>Cc1cc(Cl)nc2[nH]n(C(=O)NC3CCCc4ccccc43)c(=O)c12,,C1CCOC1,CN(C)C=O,,,test
US20150158800A1,CCCCCCCCCCCCS.CO.O=C1C=CCCC1.Oc1ccccc1>>Oc1ccc(C2CCCC(c3ccc(O)cc3)(c3ccc(O)cc3)C2)cc1,,CO,,Cl,[Na+].[OH-],test
US04084061,C1CCCCC1.Cc1ccc(Cl)cc1.O=C=O>>O=C(O)Cc1ccccc1,,C1CCCCC1,,[Na],,test
US20160264554A1,O=C(N[C@H]1CCC[C@@H](Nc2ncc(Cl)c(-c3cn(S(=O)(=O)c4ccccc4)c4ccccc34)n2)C1)c1ccc([N+](=O)[O-])cc1F>>Nc1ccc(C(=O)N[C@H]2CCC[C@@H](Nc3ncc(Cl)c(-c4cn(S(=O)(=O)c5ccccc5)c5ccccc45)n3)C2)c(F)c1,,O=C([O-])O,[Na+],CCOC(C)=O,CO,test
US20090143438A1,Cc1c(Cl)cc[n+]([O-])c1C.OCCCCCCO>>Cc1c(OCCCCCCO)cc[n+]([O-])c1C,,Cc1ccccc1,,,,test
US20090176778A1,CCOC(=O)c1cn2cc(Br)cc(C(F)(F)F)c2n1.O=C1CCC(=O)N1Cl>>CCOC(=O)c1nc2c(C(F)(F)F)cc(Br)cn2c1Cl,,CN(C)C=O,,,,test
US20090023725A1,CC(C)(C)OC(=O)NN.O=C(c1ccccn1)c1ccc(Br)cc1F>>Brc1ccc2c(-c3ccccn3)n[nH]c2c1,,CO,,CC(=O)O,,test
US20130072679A1,ClC[C@@H]1CCCN1c1cncc(Br)c1.c1nc[nH]n1>>Brc1cncc(N2CCC[C@H]2Cn2cncn2)c1,,CN(C)C=O,ClCCl,[H-].[Na+],,test
US20120316192A1,COC(=O)C#CC(=O)OC.COc1ccc2[nH]cc(CCN)c2c1.O=Cc1coc2ccccc2c1=O>>COC(=O)C1=CC(C(=O)c2ccccc2O)=CN2CCc3c([nH]c4ccc(OC)cc34)C12C(=O)OC,,Cc1ccccc1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20080194647A1,CN(C)C=O.Fc1ccc(C#Cc2cncc(Br)c2)cc1F>>O=Cc1cncc(C#Cc2ccc(F)c(F)c2)c1,,CCOC(C)=O,Cc1ccccc1,[Li]CCCC,[Cl-].[NH4+],test
US05859036,CCOC(=S)SC(=S)OCC.Cc1ccc(N)cc1>>CCOC(=S)Nc1ccc(C)cc1,,CCO,,,,test
US20110251221A1,CCI.Fc1ccc(S)c(F)c1>>CCSc1ccc(F)cc1F,,CC#N,,CCN(CC)CC,,test
US20050131017A1,COc1cccc(-c2ccc(C[C@@H](C[C@H](O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N3CCN(Cc4cccc(C)n4)C3=O)C(C)(C)C)NC(=O)OCc3ccccc3)cc2)n1>>COc1cccc(-c2ccc(C[C@H](N)C[C@H](O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N3CCN(Cc4cccc(C)n4)C3=O)C(C)(C)C)cc2)n1,[Pd],CO,,Cl,,test
US20120172426A1,CCOC(=O)NCC(OCC)OCC>>CCOC(=O)NCC=O,,C1CCOC1,,Cl,O,test
US04599357,CC(=O)SCCC(=O)Cl.CCOC(=O)C1Cc2cc(OC)c(OC)cc2N1>>CCOC(=O)C1Cc2cc(OC)c(OC)cc2N1C(=O)CCSC(C)=O,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20080221148A1,BrCc1ccccc1.Cc1c(O)cccc1C(=O)O>>Cc1c(OCc2ccccc2)cccc1C(=O)O,,C1CCOC1,CN(C)C=O,O,[H-].[Na+],test
US20160159804A1,C=C(C)C(=O)O.c1ccc(Oc2ccc(Oc3ncnc4ccn(C5CNC5)c34)cc2)cc1>>C=C(C)C(=O)N1CC(n2ccc3ncnc(Oc4ccc(Oc5ccccc5)cc4)c32)C1,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20110237628A1,COC(=O)c1cc(C)c(OCC(c2c3c(nn2-c2ccc(Cl)cc2)CCCCC3)C2CCCCC2)c(C)c1>>Cc1cc(C(=O)O)cc(C)c1OCC(c1c2c(nn1-c1ccc(Cl)cc1)CCCCC2)C1CCCCC1,,C1CCOC1,CO,[Li+].[OH-],,test
US20080019915A1,Cc1ccc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)nc1-c1cccc(O)c1.Cc1ccc(S(=O)(=O)OC[C@@H]2COC(C)(C)O2)cc1>>Cc1ccc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)nc1-c1cccc(OC[C@@H]2COC(C)(C)O2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030153566A1,COc1ccc(N(C)CC2CCOCC2)c2sc(N)nc12.O=C(O)c1ccnc(Br)c1>>COc1ccc(N(C)CC2CCOCC2)c2sc(NC(=O)c3ccnc(Br)c3)nc12,,C1CCOC1,CCOC(C)=O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05759443,O=C1CCC(=O)N1Br.OCCCCCCCCC1CCCC1>>BrCCCCCCCCC1CCCC1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150051171A1,Cn1nnn(-c2cccc(Br)c2CBr)c1=O.Oc1ccn(-c2ccc(Br)cc2)n1>>Cn1nnn(-c2cccc(Br)c2COc2ccn(-c3ccc(Br)cc3)n2)c1=O,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20090062274A1,CCOC(=O)/C=C/c1c(C)nc(SC)nc1NC(C)C>>CSc1nc(C)c2ccc(=O)n(C(C)C)c2n1,,CC(=O)O,,,,test
US20090029988A1,CC(C)(N)CN.O=[N+]([O-])c1cnc2ccccc2c1Cl>>CC(C)(N)CNN1CC([N+](=O)[O-])=Cc2ccccc21,,ClCCl,,CCN(CC)CC,,test
US04254135,CN(C(=O)c1ccc([N+](=O)[O-])cc1)[C@@H]1CN(C2CCCCC2)C[C@H]1O>>CN(C(=O)c1ccc(N)cc1)[C@@H]1CN(C2CCCCC2)C[C@H]1O,O=[Pt],CCO,,,,test
US20060154875A1,C=Cc1cc2c(s1)-c1ccccc1C(CC)N2S(=O)(=O)c1ccc(OC)cc1>>CCc1cc2c(s1)-c1ccccc1C(CC)N2S(=O)(=O)c1ccc(OC)cc1,[Pd],CCOC(C)=O,,,,test
US20090054407A1,CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)C(F)(F)F)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21.NC(=O)c1cccc(B(O)O)c1>>CC(C)(C)OC(=O)n1c(-c2ccc(-c3cccc(C(N)=O)c3)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21,,COCCOC,,O,O=C([O-])[O-].[K+].[K+],test
US20120029190A1,N#Cc1cc(F)cc(C2CCC(O)C(N=[N+]=[N-])C2)c1>>N#Cc1cc(F)cc(C2CCC(O)C(N)C2)c1,[Pd],CO,,,,test
US20080139610A1,Cc1cc(Br)cc(C)c1NC(=O)CC(C)(C)C.Clc1ccc2c(c1)CCNC2>>Cc1cc(N2CCc3cc(Cl)ccc3C2)cc(C)c1NC(=O)CC(C)(C)C,,Cc1ccccc1,,Cl,CC(C)(C)[O-].[K+],test
US04081552,Cl.N#CCCCC(=O)c1ccc(Cl)c(Cl)c1.NCCON>>Cl.N#CCCCC(=NOCCN)c1ccc(Cl)c(Cl)c1,,CCO,,Cl,c1ccncc1,test
US20150336949A1,Cc1nn(Cc2cccc(F)c2)c(C)c1-c1c[nH]c2ncc(-c3ccc(C4CCN(C(=O)OC(C)(C)C)CC4)c(F)c3)cc12>>Cc1nn(Cc2cccc(F)c2)c(C)c1-c1c[nH]c2ncc(-c3ccc(C4CCNCC4)c(F)c3)cc12,,ClCCl,O=C(O)C(F)(F)F,,,test
US20120122843A1,CNC[C@H](O)c1nc(C)cs1.Clc1ccc(CBr)c(Cl)n1>>Cc1csc([C@@H](O)CN(C)Cc2ccc(Cl)nc2Cl)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090156575A1,COC(=O)c1cccc(CC#N)c1.[OH-]>>COC(=O)c1cccc(CC(N)=O)c1,,C1CCOC1,,Cl,,test
US20110086834A1,CCC1(O)CCc2ccc(Br)cc21>>CCC1=CCc2ccc(Br)cc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100056577A1,Cc1ccnc(Br)c1.SCc1ccccc1>>Cc1ccnc(SCc2ccccc2)c1,,C1CCOC1,O,[H-].[Na+],,test
US20160152605A1,COC(=O)c1ccc([C@@H]2CCCCN2)cc1.COc1cc(C)c2c(ccn2C(=O)OC(C)(C)C)c1C(O)C(F)(F)F>>COC(=O)c1ccc([C@@H]2CCCCN2C(c2c(OC)cc(C)c3c2ccn3C(=O)OC(C)(C)C)C(F)(F)F)cc1,,CC#N,ClCCl,CCN(CC)CC,CS(=O)(=O)Cl,test
US20130059849A1,CCOC(=O)C(=O)CC(=O)C1CC1.Cc1cc(N)n(C(C)C)n1>>CCOC(=O)c1cc(C2CC2)nc2c1c(C)nn2C(C)C,,c1ccccc1,,,,test
US06156783,CC(=O)N1CCc2cc(OCC3=CCN4CCCC3C4)c(Br)cc21>>CC(=O)N1CCc2cc3c(cc21)C1(CCN2CCCC1C2)CO3,,Cc1ccccc1,,,,test
US04647658,Cc1ccccc1S(=O)(=O)Cl.O=C(Cc1ccccc1)N[C@@H]1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)C(O)CS[C@H]12>>Cc1ccc(S(=O)(=O)OC2CS[C@@H]3[C@H](NC(=O)Cc4ccccc4)C(=O)N3C2C(=O)OC(c2ccccc2)c2ccccc2)cc1,,ClCCl,,c1ccncc1,,test
US20090227570A1,CC(C)C(=O)Cl.COc1cccc2c1C(Nc1ccc3cc(N)ccc3n1)CCC2>>COc1cccc2c1C(Nc1ccc3cc(NC(=O)C(C)C)ccc3n1)CCC2,,CCN(CC)CC,,,,test
US20110207698A1,ICCI.N#Cc1c(N)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1cncs1>>N#Cc1c(N)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1cnc(I)s1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05212320,CCC(Br)c1ccc(CC(C)C)cc1.O=C(CCCn1cc(C(=O)c2cccc(NCc3ccccc3)c2)c2ccccc21)OCc1ccccc1>>CCC(c1ccc(CC(C)C)cc1)N(Cc1ccccc1)c1cccc(Cc2cn(CCCC(=O)OCc3ccccc3)c3ccccc23)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20060167000A1,BrCc1ccccc1.Cc1cnc2c(Cl)cc(Cl)c(O)c2n1>>Cc1cnc2c(Cl)cc(Cl)c(OCc3ccccc3)c2n1,,CCO,,[K+].[OH-],,test
US04028319,C[C@H](NC(=O)OC(C)(C)C)C(=O)Oc1cc(Cl)c(Cl)cc1Cl.NCC(=O)OCc1ccccc1>>C[C@H](NC(=O)OC(C)(C)C)C(=O)NCC(=O)OCc1ccccc1,,ClCCl,,,,test
US20070082912A1,CC(=O)CCC(=O)c1cc(C)ccc1OCc1ccc(F)cc1.Nc1ccc(F)c(C(=O)O)c1>>Cc1ccc(OCc2ccc(F)cc2)c(-c2ccc(C)n2-c2ccc(F)c(C(=O)O)c2)c1,,CCOC(C)=O,CN1CCCC1=O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20150087646A1,CC(C)(C)OC(=O)NNc1ccc(F)c(C(F)(F)F)c1.O=C=NC(=O)c1cc(CNC(=O)C(F)(F)F)c(F)cc1Cl>>O=C(NCc1cc(-c2nn(-c3ccc(F)c(C(F)(F)F)c3)c(=O)[nH]2)c(Cl)cc1F)C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090186912A1,CS(=O)(=O)Cl.Nc1ccc([N+](=O)[O-])c(Cl)c1>>CS(=O)(=O)Nc1ccc([N+](=O)[O-])c(Cl)c1,,C1CCOC1,Cl,c1ccncc1,,test
US20110118261A1,Brc1ccc(I)nc1.CN(C)[C@H]1CCNC1>>CN(C)[C@H]1CCN(c2ccc(Br)cn2)C1,,CN(C)C=O,,,,test
US20110172219A1,CC1(C)COc2c(F)c(F)c(N)c3c(=O)c(C#N)cn1c23.NCCCc1ccccn1>>CC1(C)COc2c(NCCCc3ccccn3)c(F)c(N)c3c(=O)c(C#N)cn1c23,,CS(C)=O,,,,test
US20120208827A1,N#Cc1cccc([N+](=O)[O-])c1Cl.NC[C@@H]1CCN(C(=O)C2CC2)C1>>N#Cc1cccc([N+](=O)[O-])c1NC[C@@H]1CCN(C(=O)C2CC2)C1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20100256200A1,N.O=S(=O)(Cl)c1ccc(Cl)nc1>>NS(=O)(=O)c1ccc(Cl)nc1,,C1COCCO1,,,,test
US20040171881A1,CCCCN1CCN(C(=O)OC(C)(C)C)c2ccc(C(=O)OC)cc21>>CCCCN1CCN(C(=O)OC(C)(C)C)c2ccc(C(=O)O)cc21,,CO,,[K+].[OH-],,test
US20070249607A1,CC(C)(C)OC(=O)N(CCCl)CCCl.COC(=O)Cc1ccccc1F>>COC(=O)C1(c2ccccc2F)CCN(C(=O)OC(C)(C)C)CC1,,CN(C)C=O,,[H-].[Na+],,test
US04008325,CCOC(=O)CC(C)=O.Cc1ccc2c(c1)CCCN2>>CC(=O)CC(=O)N1CCCc2cc(C)ccc21,c1ccncc1,Cc1ccccc1C,,,,test
US20090176770A1,C1CCOC1.Cc1cc(CC(=O)C(=O)O)cc(C)c1N>>COC(=O)[C@H](O)Cc1cc(C)c(N)c(C)c1,,C1CCOC1,,CCN(CC)CC,,test
US04156602,CCC(O)c1c(C(C)C)cc(C(C)C)cc1C(C)C.O=S(Cl)Cl>>CCC(Cl)c1c(C(C)C)cc(C(C)C)cc1C(C)C,,CCCCCC,,,,test
US20110152258A1,O=Cc1c(F)ccc(NC(=O)OCc2ccccc2)c1F.Oc1ncnc2[nH]ccc12>>COC(=O)Nc1ccc(F)c(C(O)c2c[nH]c3ncnc(O)c23)c1F,,Cl,,CO,[K+].[OH-],test
US20070208054A1,CNC(=O)Cc1ccc(Br)cc1.CNCCCc1ccc(Br)cc1>>CNCCc1ccc(Br)cc1,,C1CCOC1,,B,,test
US20100222352A1,CC(=O)CBr.Cc1ccc(NC(N)=S)cc1O>>Cc1csc(Nc2ccc(C)c(O)c2)n1,,CN(C)C=O,,,,test
US20150232465A1,CC(=O)N1c2cnc(-c3ccc(S(C)(=O)=O)cc3)cc2NC[C@@H]1C.O=C(Cl)c1ccco1>>CC(=O)N1c2cnc(-c3ccc(S(C)(=O)=O)cc3)cc2N(C(=O)c2ccco2)C[C@@H]1C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US06232290B1,CCCCCBr.COC(=O)c1cccc(O)c1>>CCCCCOc1cccc(C(=O)OC)c1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20050090669A1,CC(C)(C)OC(=O)N(C[C@H](O)c1ccc(Cl)nc1)[C@H]1CCc2ccc(-c3ccc(C(=O)O)cc3)cc2C1>>CC(C)(C)OC(=O)N(C[C@H](O)c1cccnc1)[C@H]1CCc2ccc(-c3ccc(C(=O)O)cc3)cc2C1,[Pd],CO,O,O=C[O-].[NH4+],,test
US20130102576A1,COC(=O)CN1C(=O)c2cc(N)c(OC)cc2C1=O.CS(=O)(=O)Cl>>COC(=O)CN1C(=O)c2cc(NS(C)(=O)=O)c(OC)cc2C1=O,,c1ccncc1,,,,test
US20130303524A1,NCc1ccco1.O=S(=O)(Cl)C(F)(F)F>>O=S(=O)(NCc1ccco1)C(F)(F)F,,c1ccncc1,,,,test
US04095025,O=C(O)C=Cc1cn(-c2ccccc2)nc1-c1ccc(Cl)cc1>>O=C(O)CCc1cn(-c2ccccc2)nc1-c1ccc(Cl)cc1,[Pd],CCO,,[H][H],,test
US20050288525A1,C/C=C\C[Si]1(Cl)O[C@H](c2ccccc2)[C@@H](C)N1C.O=CCCc1ccccc1>>C=C[C@H](C)[C@@H](O)CCc1ccccc1,,Cc1ccccc1,,CCOC(C)=O,Cl,test
US20160000771A1,COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3nc(Cl)c(Cc4ccc(F)cc4)[nH]3)cn2c1N1CCC(C)(C)CC1>>Cc1cc2nc(-c3ncc(Cc4ccc(F)cc4)[nH]3)cn2c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(=O)O,[Pd],CO,,[H][H],,test
US20160207929A1,COc1ccc(-c2nn(C(C)c3cc4ccccc4c(=O)n3-c3ccccc3)c3ncnc(N)c23)cc1N.CS(=O)(=O)Cl.c1ccncc1>>COc1ccc(-c2nn(C(C)c3nc4ccccc4c(=O)n3-c3ccccc3)c3ncnc(N)c23)cc1NS(C)(=O)=O,,ClCCl,,,,test
US20110195980A1,c1ccc(COc2ccnc3ccc(-c4cccc(-c5nccs5)n4)cc23)cc1>>Oc1ccnc2ccc(-c3cccc(-c4nccs4)n3)cc12,[Pd],CCO,CCOC(C)=O,,,test
US20160096834A1,CC(C)(C)c1ccc(C(=O)O)nc1.Cn1cc(-c2nc3c(-c4ccc(CN)c(F)c4)ccnc3[nH]2)cn1>>Cn1cc(-c2nc3c(-c4ccc(CNC(=O)c5ccc(C(C)(C)C)cn5)c(F)c4)ccnc3[nH]2)cn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110230486A1,COc1ccc(Sc2cc(C)c(C(=O)CBr)c(C)c2)cc1.OO>>COc1ccc(S(=O)c2cc(C)c(C(=O)CBr)c(C)c2)cc1,,ClCCl,,CC(=O)OC(C)=O,,test
US05059691,C/C(=C/C(=O)c1ccccc1)N1CCCC1.Cc1n[nH]c(N)c1C#N>>Cc1cc(-c2ccccc2)n2nc(C)c(C#N)c2n1,,CC(=O)O,,,,test
US05063225,C=C(C(=O)OC)c1ccccc1OC>>C=C(C(=O)O)c1ccccc1OC,,C1CCOC1,,[K+].[OH-],,test
US20130059834A1,CC(C)(C)OC(=O)NCC1(N)CC1.Cn1nc(-c2cnc3[nH]cc(C(=O)O)c3n2)c2ccc(F)cc21>>Cn1nc(-c2cnc3[nH]cc(C(=O)NC4(CNC(=O)OC(C)(C)C)CC4)c3n2)c2ccc(F)cc21,CN(C)c1ccncc1,CN(C)C=O,O,CCN(C(C)C)C(C)C,CCN=C=NCCCN(C)C,test
US20160096847A1,Brc1cncnc1.N#Cc1cccc(B(O)O)c1F>>N#Cc1cccc(-c2cncnc2)c1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],test
US20130172341A1,CC(C)(C)OC(=O)N1C2CCC1CC(=O)C2.COC(=O)C#N>>COC(=O)C1C(=O)CC2CCC1N2C(=O)OC(C)(C)C,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20040198779A1,CCCc1c(OCCCOc2cc(O)c(-c3ccno3)cc2CC)cccc1Oc1ccccc1C(=O)OC>>CCCc1c(OCCCOc2cc(O)c(-c3ccno3)cc2CC)cccc1Oc1ccccc1C(=O)O,,CO,,[Li+].[OH-],,test
US20080188528A1,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2.O=C(O)c1cccn(Cc2ccccc2-c2ccccc2)c1=O>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)c2cccn(Cc3ccccc3-c3ccccc3)c2=O)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150072980A1,COc1cc2c(cc1N1CCOCC1)CCC2=O.O=Cc1ncccc1C(F)(F)F>>COc1cc2c(cc1N1CCOCC1)C/C(=C\c1ncccc1C(F)(F)F)C2=O,,CCOC(C)=O,Cc1ccccc1,Cc1ccc(S(=O)(=O)O)cc1,,test
US20030045552A1,NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C(Cl)C1CCCC1>>O=C1CCC(N2C(=O)c3cccc(CNC(=O)C4CCCC4)c3C2=O)C(=O)N1,,CC#N,,C1CCC2=NCCCN2CC1,Cl,test
US20140315911A1,COC(=O)[C@H](C)N(CCC(C)C)c1nc(Cl)ncc1[N+](=O)[O-]>>CC(C)CCN1c2nc(Cl)ncc2NC(=O)C1C,[Fe],CC(=O)O,,,,test
US20050143381A1,CO.O=c1c(Cl)c(Cl)cnn1Cc1ccccc1>>COc1cnn(Cc2ccccc2)c(=O)c1Cl,,CO,ClCCl,C[O-].[Na+],,test
US20130217732A1,CN1C[C@H](C(=O)OCc2ccccc2)N(c2ccc(C#N)c(C(F)(F)F)c2)C1=O>>CN1C[C@H](C(=O)O)N(c2ccc(C#N)c(C(F)(F)F)c2)C1=O,[Pd],CO,,,,test
US20120270857A1,COC1=NC=CN2NCC3=C2C1=CC(=O)[C@H]3C1CN2CCC1CC2.Cl>>Cl.O=C1C=C2C(O)=NC=CN3NCC(=C23)[C@@H]1C1CN2CCC1CC2,,CC(=O)O,CO,Br,,test
US20100331293A1,COc1cccc(-c2nc3cc(F)cc(F)c3c(Cl)c2C)n1.Nc1cc(N2CCOCC2)cnc1N1CCOCC1>>COc1cccc(-c2nc3cc(F)cc(F)c3c(Nc3cc(N4CCOCC4)cnc3N3CCOCC3)c2C)n1,,Cc1ccccc1,,,,test
US04880775,C1COCCO1.CC1OC(C)OC(C)O1>>C1=COc2ccccc2O1,,C1COCCO1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04038396,Nc1cc([N+](=O)[O-])c[nH]c1=O.O=C(Cl)c1ccccc1>>O=C(Nc1cc([N+](=O)[O-])c[nH]c1=O)c1ccccc1,,O,,c1ccncc1,,test
US20090048295A1,CCNc1cccc2ccccc12.CCc1cccc(CC)c1-c1cc(OC)c2c(n1)CCCC2Cl.O=C(O)C(F)(F)F>>CCc1cccc(CC)c1-c1cc(OC)c2c(n1)CCCC2N(CC)c1cccc2ccccc12.O=C(O)C(F)(F)F,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20040044052A1,CCN.CCOC(=O)C1CN(c2ccc(N3C=CC(=O)CC3)c(F)c2)C(=O)O1>>CCNC(=O)[C@H]1CN(c2ccc(N3C=CC(=O)CC3)c(F)c2)C(=O)O1,,CO,,,,test
US20150183802A1,BrCCBr.CC(C)(C)OC(=O)N1C(=O)Cc2ccc(F)cc21>>CC(C)(C)OC(=O)N1C(=O)C2(CC2)c2ccc(F)cc21,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070173504A1,CCOc1cccc(S(=O)(=O)c2cnc(Nc3cc(C#CCOC)nc(C)n3)s2)c1>>CCOc1cccc(S(=O)(=O)c2cnc(Nc3cc(CCCOC)nc(C)n3)s2)c1,[Pd],C1CCOC1,CCOC(C)=O,,,test
US20130035354A1,N#Cc1ccc(-c2cncc(N)c2)cc1Cl.O=S(=O)(Cl)CC(F)(F)F>>N#Cc1ccc(-c2cncc(NS(=O)(=O)CC(F)(F)F)c2)cc1Cl,,c1ccncc1,,,,test
US20050250775A1,CON(C)C(=O)[C@@H]1CN(C(=O)OC(C)(C)C)CCO1.Fc1cccc([Mg]Br)c1>>CC(C)(C)OC(=O)N1CCO[C@H](C(=O)c2cccc(F)c2)C1,,C1CCOC1,,,,test
US20070244159A1,N#CC1(c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)CC1>>N#CC1(c2ccc(O)c(O)c2)CC1,[Pd],CO,,,,test
US20090137561A1,COC(=O)c1cc(CO)ccc1-c1cc(F)ccc1F.[Li]C(C)(C)C>>CC(C)(C)C(=O)c1cc(CO)ccc1-c1cc(F)ccc1F,,C1CCOC1,,,,test
US20140323486A1,COC(=O)c1ccc[nH]1.O=[N+]([O-])c1ccc(F)cc1>>COC(=O)c1cccn1-c1ccc([N+](=O)[O-])cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20040006067A1,CC(C)(C)OC(=O)N1CC(C(=O)N[C@H](Cc2ccc(Cl)cc2)C(=O)N2CCC(c3ccccc3-n3cc[nH]c3=O)CC2)C1>>O=C(N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(c2ccccc2-n2cc[nH]c2=O)CC1)C1CNC1,,CCOC(C)=O,,Cl,,test
US05668137,CC(C)(Cc1ccc(Br)cc1)C(=O)O.COB(OC)OC>>CC(C)(Cc1ccc(B(O)O)cc1)C(=O)O,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US07030267B2,CCOC(=O)C(C#N)=CCC(C)C.C[N+](=O)[O-]>>CCOC(=O)C1(C#N)CC1CC(C)C,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20140288081A1,N#CSc1c(F)cccc1[N+](=O)[O-]>>Nc1nc2cccc(F)c2s1,,O,,CCO,Cl,test
US20160046596A1,Nc1ccc(F)c(Cl)c1.O=Cc1cc(F)nc(F)c1O>>Oc1c(C=Nc2ccc(F)c(Cl)c2)cc(F)nc1F,,CC#N,,,,test
US20160221945A1,CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)O.COc1cnc(-c2cnc(C(F)(F)F)nc2)cc1CN>>COc1cnc(-c2cnc(C(F)(F)F)nc2)cc1CNC(=O)[C@@H]1C[C@@H](F)CN1C(=O)OC(C)(C)C,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04716168,Nc1cc([N+](=O)[O-])ccc1NC(=O)c1ccco1>>O=[N+]([O-])c1ccc2nc(-c3ccco3)[nH]c2c1,,O,,Cl,[NH4+].[OH-],test
US05565485,CCCc1cc(C(=O)OC)ccc1OC(C(=O)OCC)c1ccc2c(c1)OCO2>>CCCc1cc(C(=O)OC)ccc1OC(C(=O)O)c1ccc2c(c1)OCO2,,CO,,,,test
US20130005707A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1NCCc2cc(Br)ccc21>>CC(C)(C)OC(=O)N1CCc2cc(Br)ccc2C1=O,CN(C)c1ccncc1,ClCCl,,,,test
US03935223,CCOC(=O)CC(=N)N.O=C1CCCC(=O)C1.O=Cc1cccc2ccccc12>>CCOC(=O)C1=C(N)NC2=C(C(=O)CCC2)C1c1cccc2ccccc12,,CCO,,CN(C)C=O,,test
US20080242683A1,CCn1nnc([C@H]2O[C@@H](n3cnc4c(NCC(c5ccccc5)c5ccccc5)nc(N5CC[C@@H](N)C5)nc43)[C@H](O)[C@@H]2O)n1.COc1c(OC)c(=O)c1=O>>CCn1nnc([C@H]2O[C@@H](n3cnc4c(NCC(c5ccccc5)c5ccccc5)nc(N5CC[C@@H](Nc6c(OC)c(=O)c6=O)C5)nc43)[C@H](O)[C@@H]2O)n1,,CCO,,O=C(O)C(F)(F)F,,test
US04070531,CCCCCCC(O)CN.OCC1CO1>>CCCCCCC(O)CNCC(O)CO,,Cc1ccccc1,,,,test
US20160122341A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(C(=O)NNC(=O)CC(C)(C)NC(=O)OC(C)(C)C)n2c1>>Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(-c3nnc(CC(C)(C)NC(=O)OC(C)(C)C)s3)n2c1,,C1CCOC1,,,,test
US20140303158A1,CCOC(=O)c1cc(Br)ccc1OC(F)(F)F.COC(OC)OC.NN.OB(O)c1ccc2nnc(C(F)(F)F)n2c1>>FC(F)(F)Oc1ccc(-c2ccc3nnc(C(F)(F)F)n3c2)cc1-c1nnco1,,CCO,,O,,test
US20060084673A1,CC(=O)OC(C)=O.NC1=NC(=O)CN1C(=O)OCc1ccccc1>>CC(=O)NC1=NC(=O)CN1C(=O)OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20100076026A1,CCOC(=O)c1ccc(N=C=O)cc1.c1ccc(-n2nc3ccccc3c2NC2CCCCC2)cc1>>CCOC(=O)c1ccc(NC(=O)N(c2c3ccccc3nn2-c2ccccc2)C2CCCCC2)cc1,,Cc1ccccc1,,,,test
US04525203,CC(C)(C)N.O=CC1CCC=CO1>>CC(C)(C)N=CC1CCC=CO1,,CCO,,,,test
US20150018547A1,CI.COC(=O)C1COc2cc(OCc3ccc(Cl)cc3Cl)ccc21>>COC(=O)C1(C)COc2cc(OCc3ccc(Cl)cc3Cl)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20150336991A1,COC(=O)c1nc(Cl)ccc1F.CS(=O)(=O)c1ccc(O)cn1>>COC(=O)c1nc(Cl)ccc1Oc1ccc(S(C)(=O)=O)nc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05141930,CC(=O)Cl.O=C1c2ccsc2SCCN1CCCCCl>>CC(=O)c1cc2c(s1)SCCN(CCCCCl)C2=O,,ClCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20130150333A1,CCNc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>CCN(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)S(=O)(=O)c1ccc([N+](=O)[O-])cc1,,c1ccncc1,,CN(C)c1ccccn1,,test
US20070208018A1,COC(=O)c1cn(-c2cc3c(=O)n(NS(C)(=O)=O)c(=O)[nH]c3cc2C(F)(F)F)cn1.NC=O>>CS(=O)(=O)Nn1c(=O)[nH]c2cc(C(F)(F)F)c(-n3cnc(C(N)=O)c3)cc2c1=O,,CN(C)C=O,,C[O-].[Na+],,test
US20160151367A1,CCOC(=O)c1cnc2n1CCNC2.O=C(O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F>>CCOC(=O)c1cnc2n1CCN(C(=O)c1cc(Cc3n[nH]c(=O)c4ccccc34)ccc1F)C2,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080171772A1,CCOC(=O)c1ccc2c(C(=O)O)c(C(C)C)n(Cc3ccccc3)c2c1.NCc1ccc(F)c(F)c1>>CCOC(=O)c1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3ccccc3)c2c1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,ClCCCl,,test
US05068320,CCCCCCCCC(=O)Cl.OC[C@@H]1CC[C@H](n2cnc3c(NCC4CC4)ncnc32)O1>>CCCCCCCCC(=O)OC[C@@H]1CC[C@H](n2cnc3c(NCC4CC4)ncnc32)O1,CN(C)c1ccncc1,CC#N,,CCN(CC)CC,,test
US20140163000A1,CC1(CC=O)OCCO1.NNc1c(Br)cncc1[N+](=O)[O-]>>Cc1ccnn1-c1c(Br)cncc1[N+](=O)[O-],,CCO,,,,test
US20050288316A1,COc1ccc2[nH]c3c(c2c1)CCNC31CCNC1.Cc1ccc2[nH]cc(CCOS(C)(=O)=O)c2c1>>COc1ccc2[nH]c3c(c2c1)CCNC31CCN(CCc2c[nH]c3ccc(C)cc23)C1,,CC#N,CO,CCN(CC)CC,,test
US20110306609A1,CC(C)(C)OC(=O)c1nc(-c2ccccc2)sc1CN1CCCC1.Cl>>Cl.O=C(O)c1nc(-c2ccccc2)sc1CN1CCCC1,,C1CCOC1,,,,test
US20090311217A1,CNC.COc1ccc2[nH]c(C(=O)O)cc2c1>>COc1ccc2[nH]c(C(=O)N(C)C)cc2c1,,ClCCl,,O,O=C(n1ccnc1)n1ccnc1,test
US05753679,Cc1ccc(C(=O)OC2CCN(Cc3ccc([N+](=O)[O-])cc3)CC2)cc1>>Cc1ccc(C(=O)OC2CCN(Cc3ccc(N)cc3)CC2)cc1,[Ni],CCO,,,,test
US20120283297A1,CCOC(=O)CCCn1cc2cc(-c3noc(-c4cnc(OC(C)C)c(Cl)c4)n3)c(CC)cc2n1>>CCc1cc2nn(CCCC(=O)O)cc2cc1-c1noc(-c2cnc(OC(C)C)c(Cl)c2)n1,,CO,,[Na+].[OH-],,test
US05155100,COC(=O)[C@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)OC(C)(C)C.Cl>>COC(=O)[C@@H](N)Cc1ccc(-c2ccccc2)cc1.Cl,,CCOC(C)=O,,,,test
US06599917B1,CO[C@H]1CN(c2cccc(Cc3ccccc3)n2)C[C@H]1OCF.O=C1CCC(=O)N1I>>CO[C@H]1CN(c2ccc(I)c(Cc3ccccc3)n2)C[C@H]1OCF,,O,,CN(C)C=O,,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4cscn4)nc(Cl)c3n2)cc1.Nc1ccc2c(c1)NC(=O)CC2>>O=C1CCc2ccc(Nc3nc(-c4cscn4)nc4cn[nH]c34)cc2N1,C1COCCO1,CO,,Cl,,test
US20130296338A1,CCOC(=O)c1cc2cccc(Cl)c2nc1-c1cccnc1>>OCc1cc2cccc(Cl)c2nc1-c1cccnc1,,Cc1ccccc1,,CC(C)C[AlH]CC(C)C,,test
US04327099,CC1(C)Oc2cc([N+](=O)[O-])c(N)cc2[C@@H](N2CCCCC2)[C@@H]1O>>CC1(C)Oc2cc(N)c(N)cc2[C@@H](N2CCCCC2)[C@@H]1O,[Pd],CCO,,[H][H],,test
US20070249585A1,CS(=O)(=O)Cl.Clc1ccc2c(c1)CNCc1nnc(N3CCC(c4ccccn4)CC3)n1-2>>CS(=O)(=O)N1Cc2cc(Cl)ccc2-n2c(nnc2N2CCC(c3ccccn3)CC2)C1,,ClCCl,O,CCN(CC)CC,,test
US20070105943A1,CC(C)=O.CCOP(=O)(Cc1cccc(C#N)c1)OCC>>CC(C)=Cc1cccc(C#N)c1,,C1CCOC1,,O,[H-].[Na+],test
US04127661,C.CC(O)COc1ccccc1.O=S(=O)(O)Cl>>CC(COc1ccccc1)OS(C)(=O)=O,,c1ccncc1,,,,test
US20060247233A1,CCOC(=O)c1ccc2c(c1)OCO2.Cc1cccc(C)n1>>Cc1cccc(CC(=O)c2ccc3c(c2)OCO3)n1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20140005393A1,CCOC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(-c3ccc(F)cc3)cc2)c2ncc3ccccc3c2C)cc1>>Cc1c(N(Cc2ccc(-c3ccc(F)cc3)cc2)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12,,CO,,Cl,[Na+].[OH-],test
US20070173498A1,CN(C)CC1CCc2cc(O)ccc2C1.COc1ccc(COc2ccc(CO)cc2)cc1>>COc1ccc(COc2ccc(COc3ccc4c(c3)CCC(CN(C)C)C4)cc2)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140378686A1,CS(=O)(=O)Cl.N#Cc1cccc(-c2nn([C@@H]3c4cc(Cl)cc(Cl)c4C[C@H]3O)c3c2CNCC3)c1>>CS(=O)(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(Cl)cc(Cl)c3C[C@H]2O)C1,,C1CCOC1,,CCN(CC)CC,,test
US04333942,CC(=O)Cl.CN1CCC(Oc2ccc(N)cc2)(c2ccccc2)CC1>>CC(=O)Nc1ccc(OC2(c3ccccc3)CCN(C)CC2)cc1,,c1ccccc1,,CCN(CC)CC,,test
US03953501,CC(=O)Cl.CNC(=O)C(CO)NC(=O)c1c(I)c(N)c(I)c(C(=O)O)c1I>>CC(=O)Nc1c(I)c(C(=O)O)c(I)c(C(=O)NC(=O)CN)c1I,,CC(=O)N(C)C,,O,,test
US20130144054A1,C[C@@H](COS(C)(=O)=O)NS(=O)(=O)c1ccccc1[N+](=O)[O-].NCCCO>>C[C@@H](CNCCCO)NS(=O)(=O)c1ccccc1[N+](=O)[O-],,CC#N,,,,test
US04123250,CCC(C)N.Cc1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1Cl>>CCC(C)Nc1c([N+](=O)[O-])cc(C)c(Cl)c1[N+](=O)[O-],,C1CCCCC1,,,,test
US04409228,CC(=O)Nc1ccncc1.Cc1cccc(Cl)n1>>CC(=O)NC1CCN(c2cccc(C)n2)CC1,,O=S1(=O)CCCC1,,O=C([O-])[O-].[K+].[K+],,test
US20100063101A1,CCOC(=O)C(C)(C)Br.Oc1ccc(OCc2ccccc2)nc1>>CCOC(=O)C(C)(C)Oc1ccc(OCc2ccccc2)nc1,,O,,C1CCOC1,,test
US20150368238A1,CS(=O)(=O)Cl.OC1CCOC1>>CS(=O)(=O)O[C@H]1CCOC1,,ClCCl,,CCN(CC)CC,,test
US20100298324A1,COC(=O)c1ccc(C(=O)O)cc1N.NCc1ccc(Cl)cc1>>COC(=O)c1ccc(C(=O)NCc2ccc(Cl)cc2)cc1N,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04185992,C[Mg]I.O=Cc1ccc(OC(F)(F)F)cc1>>CC(O)c1ccc(OC(F)(F)F)cc1,,CCOCC,O,[Cl-].[NH4+],,test
US04954518,COc1ccc(Oc2ccccc2)c(N)c1.CS(=O)(=O)Cl>>COc1ccc(Oc2ccccc2)c(NS(C)(=O)=O)c1,,c1ccncc1,,CCOC(C)=O,O,test
US20090099200A1,CCOC(=O)CO.NC(=NO)c1cnc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)s1>>OCc1nc(-c2cnc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)s2)no1,,CCO,,[Na],,test
US20150210688A1,Cc1nc(C(F)(F)F)c[nH]1.O=C1CCC(=O)N1I>>Cc1nc(C(F)(F)F)c(I)[nH]1,,CC#N,O,,,test
US06187770B1,CCOC(=O)Cl.CN1CCN2c3ccccc3Oc3ccccc3C2C1>>CCOC(=O)C1NCCN2c3ccccc3Oc3ccccc3C12,,Cc1ccccc1,,,,test
US05187161,CI.CN(C)C=O.COc1cc2c(c(C(C)(C)C)c1)OC(=O)C2>>COc1cc(C(C)(C)C)c2c(c1)C(C)(C)C(=O)O2,,O,,[H-].[Na+],,test
US20110077235A1,O=C(Cl)C(=O)Cl.O=C(O)[C@@H]1C[C@H]1c1ccccc1>>O=C(Cl)[C@@H]1C[C@H]1c1ccccc1,,ClCCl,,,,test
US20040192721A1,O=C1CCC(=O)N1Br.Oc1cccc2ccccc12>>O=C1C=C(Br)C(=O)c2ccccc21,,O,,CC(=O)O,,test
US05807846,CC(C)c1cccc(C(C)C)c1Br.O=C=O>>CC(C)c1cccc(C(C)C)c1C(=O)O,,Cl,,[Li]CCCC,,test
US20060173002A1,CC(C)(C)OC(=O)NN.CC(C)(C)c1ccccc1Oc1ncccc1N=C=S>>CC(C)(C)c1ccccc1Oc1ncccc1NC(=S)NN,,ClCCl,,O=C(O)C(F)(F)F,,test
US04885283,C(=NC1CCCCC1)=NC1CCCCC1.C1CCOC1.CCN1CCOCC1.CCOP(=O)(CN)CC(CC(C)C)C(=O)OCc1ccccc1.CO.Oc1cccc2[nH]nnc12>>CCOP(=O)(CNC(=O)CN1C(=O)c2ccccc2C1=O)CC(CC(C)C)C(=O)OCc1ccccc1,,CO,ClC(Cl)Cl,,,test
US04920128,COc1ccc2cc3c(N)nn(C)c3nc2c1>>Cn1nc(N)c2cc3ccc(O)cc3nc21,,Br,,,,test
US20130059833A1,CS(=O)(=O)Cl.OCc1nc(-c2ccccc2)oc1-c1cccnc1>>ClCc1nc(-c2ccccc2)oc1-c1cccnc1,,ClCCl,,CCN(CC)CC,,test
US20040106621A1,C#CCN(C)C.C[C@H](NC(=O)OC(C)(C)C)c1cccc(C=NO)c1>>C[C@H](N)c1cccc(-c2cc(CN(C)C)on2)c1,,ClCCl,,,,test
US05455260,COC(=O)[C@H](CO)N(O[Si](C)(C)C(C)(C)C)C(c1ccccc1)(c1ccccc1)c1ccccc1>>OCC(CO)NC(c1ccccc1)(c1ccccc1)c1ccccc1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110251173A1,C[C@@H](O)CN(C(=O)c1c(Cl)ncnc1Cl)c1ccc(OCc2ccccc2)cc1>>C[C@@H]1CN(c2ccc(OCc3ccccc3)cc2)C(=O)c2c(Cl)ncnc2O1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US06352993B1,COCc1nc(Cl)nc(N2CCc3ccccc3C2C)c1C.Cc1ccccc1N>>COCc1nc(Nc2ccccc2C)nc(N2CCc3ccccc3C2C)c1C.Cl,,CN(C)C=O,,CCN(CC)CC,,test
US20060223835A1,O=C(c1ccccc1)n1c(=O)c(F)cn([C@@H]2C[C@H](COCc3ccccc3)C2)c1=O>>O=c1[nH]c(=O)n([C@@H]2C[C@H](COCc3ccccc3)C2)cc1F,,CCO,,CN,,test
US20040082805A1,COCOc1ccc(CCC2CCCC(O)CCC2)cc1>>COCOc1ccc(CCC2CCCC(=O)CCC2)cc1,,CCOCC,ClCCl,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20100144695A1,COc1ccc(C2(O)CCC(N3CC(NC(=O)CN)C3)CC2)cn1.O=C(Cl)c1ccc(Cl)c(Cl)c1>>COc1ccc(C2(O)CCC(N3CC(NC(=O)CNC(=O)c4ccc(Cl)c(Cl)c4)C3)CC2)cn1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20080021022A1,Cc1ccc(-c2oncc2C(=O)Cl)cc1.c1ccc2c(C3CCNCC3)c[nH]c2c1>>Cc1ccc(-c2oncc2C(=O)N2CCC(c3c[nH]c4ccccc34)CC2)cc1,,ClCCl,,,,test
US20060052449A1,CCOC(=O)c1cccc(-c2ccc(CBr)cc2)c1.CCOC(=O)c1ccccc1-c1ccc(C)cc1.O=C1CCC(=O)N1Br>>CCOC(=O)c1ccccc1-c1ccc(CBr)cc1,CC(C)(C#N)N=NC(C)(C)C#N,ClC(Cl)(Cl)Cl,,,,test
US20130190309A1,O=c1c2c([N+](=O)[O-])cccc2cnn1-c1cccc(C(F)(F)F)c1>>Nc1cccc2cnn(-c3cccc(C(F)(F)F)c3)c(=O)c12,[Pd],CCOC(C)=O,,[H][H],,test
US20040167121A1,Clc1nc(Cl)c2cc(I)ccc2n1.Nc1cc(C2CC2)n[nH]1>>Clc1nc(Nc2cc(C3CC3)n[nH]2)c2cc(I)ccc2n1,,CCO,,,,test
US20110183988A1,CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4cnn(C5CCN(C(=O)OC(C)(C)C)CC5)c4)cc23)c1F>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4cnn(C5CCNCC5)c4)cc23)c1F,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20160120868A1,C=CC(=O)Cl.Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)c(Cl)c1)nn2[C@@H]1CCCNC1>>C=CC(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4ccccc4)c(Cl)c3)c3c(N)ncnc32)C1,,ClCCl,,CCN(CC)CC,O,test
US20140135496A1,C=O.Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(N)=O>>Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(=O)NCO,,C1COCCO1,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US04031088,COC(=O)CCCCC(=O)Nc1c(I)c(C(=O)O)c(I)c(N(C)C(C)=O)c1I>>CC(=O)N(C)c1c(I)c(NC(=O)CCCCC(=O)O)c(I)c(C(=O)O)c1I,,O,,Cl,[Na+].[OH-],test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4ccncc4nn23)CC1.Cl>>Cl.O=c1cc(C2CCNCC2)n2nc3cnccc3c2[nH]1,,C1COCCO1,CO,,,test
US20080167287A1,COCC1(NC(=O)OC(C)(C)C)CCOCC1.Cl>>COCC1(N)CCOCC1.Cl,,C1COCCO1,CCOC(C)=O,,,test
US20080261969A1,Fc1cc2[nH]c(=S)[nH]c2c(F)c1F.O=Cc1ccc([N+](=O)[O-])o1>>O=Cc1ccc(Sc2nc3c(F)c(F)c(F)cc3[nH]2)o1,,C1CCOC1,,[H-].[Na+],,test
US20040224997A1,COC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(-c2ccc(N)c(F)c2)cc1.Cc1ccc2nc(S(C)(=O)=O)oc2c1>>Cc1ccc2nc(Nc3ccc(-c4ccc(C(=O)[C@@H]5CCC[C@H]5C(=O)O)cc4)cc3F)oc2c1,,CC(Cl)Cl,,[Na+].[OH-],,test
US20140018319A1,CCN(Cc1ccc(OC)cc1)c1nc(Cl)nn2c(Br)cnc12.N#C[Cu]>>CCN(Cc1ccc(OC)cc1)c1nc(Cl)nn2c(C#N)cnc12,,CN1CCCC1=O,,,,test
US20130131039A1,CCOP(=O)(CC#N)OCC.O=C1CC2(COC2)C1>>N#CC=C1CC2(COC2)C1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20120252792A1,Nc1cccc(C(=O)O)c1.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>O=C(O)c1cccc(NC(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1,,ClCCl,,CCN(CC)CC,,test
US20110152238A1,CCN(CC)C(=O)c1ccc(C(c2cccc(OC)c2)N2C3CCC2C2CCC3N2Cc2ccccc2)cc1>>CCN(CC)C(=O)c1ccc(C(c2cccc(OC)c2)N2C3CCC2C2CCC3N2)cc1,[Pd],CCO,,,,test
US20100160583A1,CC(=O)c1ccccn1.Nc1ccccc1O>>OC1C=CC=CC1=NCCc1ccccn1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20130131017A1,COC(=O)c1ccc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)n2cccc12>>O=C(O)c1ccc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)n2cccc12,,C1CCOC1,O,Cl,[Na+].[OH-],test
US04563455,N#CCc1nc2ccccc2n1-c1ccccc1.N#CN=C(N)N>>Nc1nc(N)nc(Cc2nc3ccccc3n2-c2ccccc2)n1,,COCCO,,[K+].[OH-],,test
US20100056576A1,COC(=O)c1ccc(F)c(-c2c(F)ccc(O)c2F)n1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1ccc(F)c(-c2c(F)ccc(OS(=O)(=O)C(F)(F)F)c2F)n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040116487A1,CCO[C@H](C(=O)OC)[C@H](O)c1ccc(OCc2ccccc2)cc1C(F)(F)F>>CCO[C@@H](Cc1ccc(OCc2ccccc2)cc1C(F)(F)F)C(=O)OC,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US04975459,Cc1ccccc1.Nc1ccc(N)c2c1C(=O)c1ccccc1C2=O.O=C(Cl)C1CC1.O=C1c2ccccc2C(=O)c2ccccc21>>O=C1c2ccccc2C(=O)c2c(NC(=O)C3CC3)ccc(NC(=O)C3CC3)c21,,Cc1ccccc1,,CCN(CC)CC,,test
US05039805,N=C(NCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc(C(=O)NCCC(=O)OCc2ccccc2)c1)N[N+](=O)[O-].O=CO>>N=C(N)NCCC[C@H](N)C(=O)Nc1cccc(C(=O)NCCC(=O)O)c1.O=CO,[Pd],O=CO,,,,test
US20090233924A1,COc1cc(O)ccc1CC(=O)Nc1ccc(N(C)C)cn1.COc1cc2ncnc(Cl)c2cc1OC>>COc1cc(Oc2ncnc3cc(OC)c(OC)cc23)ccc1CC(=O)Nc1ccc(N(C)C)cn1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20110136763A1,COCOc1cc(COC)c(C=O)c(OCOC)c1>>COCc1cc(O)cc(O)c1C=O,,C1CCOC1,CCOC(C)=O,Cl,,test
US06093732,CCOC(=O)c1cnc2cc(F)ccc2c1O.NCc1ccc(Cl)cc1>>O=C(NCc1ccc(Cl)cc1)c1cnc2cc(F)ccc2c1O,,Cc1ccccc1,,C[Al](C)C,Cl,test
US20160002255A1,COC(=O)[C@@H](C)[C@H](c1ccc(I)c(O[C@@H](CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C2CN(C(=O)OC(C)(C)C)C2)c1)C1CC1>>COC(=O)[C@@H](C)[C@H](c1ccc(I)c(O[C@@H](CO)C2CN(C(=O)OC(C)(C)C)C2)c1)C1CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110053922A1,COC(=O)[C@H]1CC[C@@]2(CCN(C(=O)N(C)[C@H](C)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H](c3ccc(F)cc3C)C2)N1>>Cc1cc(F)ccc1[C@H]1C[C@]2(CC[C@H](CO)N2)CCN1C(=O)N(C)[C@H](C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,C1CCOC1,,[BH4-].[Li+],,test
US20110190351A1,CN(C)C=O.COc1ccc(C(=O)[O-])c2nc(-c3cccs3)[nH]c12.NC(=O)c1ccc(Cl)nc1>>COc1ccc(C(=O)NCCOc2ccc(C(N)=O)cn2)c2nc(-c3cccs3)[nH]c12,,CN(C)C=O,,[H-].[Na+],,test
US20100004280A1,CCC(C)(C)CC(O)CNC(=O)C1(Cc2ccc(-c3ccc(F)cn3)cc2)CCCN1C(=O)OC(C)(C)C>>CCC(C)(C)CC(=O)CNC(=O)C1(Cc2ccc(-c3ccc(F)cn3)cc2)CCCN1C(=O)OC(C)(C)C,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20140228405A1,CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(N)cc1.O=C(Cl)c1cccc(Br)c1>>CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(NC(=O)c2cccc(Br)c2)cc1,,CC#N,,CCN(CC)CC,O,test
US20140155419A1,Br[Mg]c1ccccc1.Cc1ccc(C#N)c(Cl)c1>>Cc1ccc(C(N)c2ccccc2)c(Cl)c1,,C1CCOC1,,CO,[BH4-].[Na+],test
US05543278,Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1.S=C(Cl)Cl>>FC(F)(F)c1cc(N=C=S)cc(C(F)(F)F)c1,,ClC(Cl)Cl,,O,,test
US20110224339A1,CCCCOP(=O)(CC)CC(C)CO>>CCP(=O)(O)CC(C)CO,,CCCCO,O,,,test
US20060122394A1,C[C@@H]1CNCCN1.Clc1cc(Br)cnc1Br>>C[C@@H]1CN(c2ncc(Br)cc2Cl)CCN1,,CC(=O)N(C)C,,,,test
US05925596,Cc1ccc(S(C)(=O)=O)c(S(=O)(=O)NC(C)(C)C)c1.O=C1CCC(=O)N1Br>>CC(C)(C)NS(=O)(=O)c1cc(CBr)ccc1S(C)(=O)=O,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US03947470,CCNCC.O=C(c1ccc(OCCCCBr)cc1)c1c(-c2ccccc2)oc2ccccc12>>CCN(CC)CCCCOc1ccc(C(=O)c2c(-c3ccccc3)oc3ccccc23)cc1,,CCO,,,,test
US04935424,C1=COCC1.NC(N)=S>>Nc1ncc(CCO)s1,,O,,O=C1CCC(=O)N1Br,,test
US20070167475A1,CC(C)N.O=C(O)c1ccnc(Cl)c1>>CC(C)NC(=O)c1ccnc(Cl)c1,CN(C)C=O,CC#N,O,CCN(CC)CC,O=S(Cl)Cl,test
US20060111375A1,CC(=O)c1cc(Cl)c(C)cc1O.COc1cc2nccc(Cl)c2cc1OC>>COc1cc2nccc(Oc3cc(C)c(Cl)cc3C(C)=O)c2cc1OC,CN(C)c1ccncc1,Clc1ccccc1Cl,,O,,test
US20120295897A1,CC(C)CCN.O=CCCN1C(=O)C2(COc3cc4c(cc32)CCO4)c2ccccc21>>CC(C)CCNCCCN1C(=O)C2(COc3cc4c(cc32)CCO4)c2ccccc21,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20060172994A1,FC(F)(F)c1cc(Cl)nc(Cl)n1.Nc1ccc(Cl)cc1>>FC(F)(F)c1cc(Nc2ccc(Cl)cc2)nc(Cl)n1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20020091111A1,CCCCCCCCCCCCCCCCCCCC(=O)Cl.COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@@H](N)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C>>CCCCCCCCCCCCCCCCCCCC(=O)N[C@H]1CC[C@]2(C)[C@H]3C[C@H](O)[C@]4(C)[C@@H]([C@H](C)CCC(=O)OC)CC[C@H]4[C@@H]3[C@H](O)C[C@@H]2C1,,CN(C)C=O,,CCN(CC)CC,O,test
US20090137561A1,C1=COCCC1.COC(=O)c1ccc(O)c(Br)c1>>COC(=O)c1ccc(OC2CCCCO2)c(Br)c1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20030153752A1,Cc1ccc(S(=O)(=O)OC2CCOC2)cc1.Clc1ncnc2[nH]cc(I)c12>>Clc1ncnc2c1c(I)cn2C1CCOC1,,CN(C)C=O,O,[H][H],[H-].[Na+],test
US20060211739A1,BrCc1cccnc1.Clc1cccc(-c2nnn[nH]2)c1Cl>>Clc1cccc(-c2nnnn2Cc2cccnc2)c1Cl,,CC#N,CCOC(C)=O,Br,CCN(CC)CC,test
US20100120761A1,CC#CC(=O)c1ccn2ccnc2c1.NO>>Cc1cc(-c2ccn3ccnc3c2)no1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20100278733A1,CC(=O)c1ccc(I)cc1.CN(C)c1ccc(C=O)o1>>CN(C)c1ccc(C=CC(=O)c2ccc(I)cc2)o1,,CCO,,[K+].[OH-],,test
US20090176778A1,Fc1cccc(C2CCNC2)c1.O=C(Cl)c1nc2c(C(F)(F)F)cc(-c3coc(Cl)c3)cn2c1Cl>>O=C(c1nc2c(C(F)(F)F)cc(-c3coc(Cl)c3)cn2c1Cl)N1CCC(c2cccc(F)c2)C1,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,Cl,test
US20060287522A1,O=S(=O)(Cl)c1ccc(Br)cc1.c1ccc2c(c1)Cn1cccc1CN2>>O=S(=O)(c1ccc(Br)cc1)N1Cc2cccn2Cc2ccccc21,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080194549A1,CCc1ccc(C(=O)OC)cc1O.OCCCBr>>CCc1ccc(C(=O)OC)cc1OCCCO,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20130237519A1,COC(=O)c1cnc(C)c(N)c1.O=C(O)c1cnn2cc(Br)ccc12>>COC(=O)c1cnc(C)c(NC(=O)c2cnn3cc(Br)ccc23)c1,,Cc1ccccc1,,O=S(Cl)Cl,c1ccncc1,test
US20090181956A1,CCOC(=O)c1cc(C)nn1-c1ncccc1Cl>>Cc1cc(C(=O)O)n(-c2ncccc2Cl)n1,,O,,CO,[Na+].[OH-],test
US20040229909A1,CC(=O)c1c(O)cc(O)cc1O.Fc1ccc(CBr)cc1>>CC(=O)c1c(O)cc(O)cc1OCc1ccc(F)cc1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20030181456A1,CCOC(=O)N1CCC(CNC(=O)c2cc(Cl)cc3c2OCCO3)C(OC)C1>>CO[C@@H]1CNCC[C@@H]1CNC(=O)c1cc(Cl)cc2c1OCCO2,,CCO,,[K+].[OH-],,test
US20130203775A1,COC(=O)c1cc(I)c(C)cc1OC>>COc1cc(C)c(I)cc1C(=O)O,,CCO,,[Na+].[OH-],,test
US20110003787A1,COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(-c2ccc(C3=NC[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)O3)[nH]2)c1>>COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(-c2ccc(C3=NC[C@H](CO)O3)[nH]2)c1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05078907,CCCCO.CCOC(=O)c1ccc(C(=O)OCC)cc1.Cc1ccccc1.O=C(Cl)c1ccc(C(=O)Cl)cc1>>CCCCOC(=O)c1ccc(C(=O)OCCCC)cc1,,Cc1ccccc1,,,,test
US20030100552A1,CC(C)(C)C1Nc2cccc3cccc(c23)S1(=O)=O>>O=S1(=O)CNc2cccc3cccc1c23,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160166560A1,COc1ccc(CN2CCC(N(C)C(=O)n3cnc(-c4cccc(NS(C)(=O)=O)c4)c3)CC2)cc1OC.Cl>>COc1ccc(CN2CCC(N(C)C(=O)n3cnc(-c4cccc(NS(C)(=O)=O)c4)c3)CC2)cc1OC.Cl,,CCOC(C)=O,,,,test
US20120329830A1,COc1ccc(CNc2nc3ccc(Br)cc3cc2/C=C/C(=O)NCC2CCCCC2)cc1>>COc1ccc(CNc2nc3ccc(Br)cc3cc2CCC(=O)NCC2CCCCC2)cc1,[Pt],CCO,,,,test
US20120083488A1,CC1(C)OCC(/C=C/c2ccc3c(c2)C(C)(C)c2oc4ccccc4c2C3=O)O1>>CC1(C)c2cc(CCC(O)CO)ccc2C(=O)c2c1oc1ccccc21,[Pd],CO,,,,test
US20150259367A1,CC(C)(C)OC(=O)N1CC(C(=O)Nc2ccccc2Br)C1.COc1ccc(CCl)cc1>>COc1ccc(CN(C(=O)C2CN(C(=O)OC(C)(C)C)C2)c2ccccc2Br)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20050215605A1,COC(=O)C1SCCN1S(=O)(=O)c1ccc(-c2ccccc2)cc1>>O=C(O)C1SCCN1S(=O)(=O)c1ccc(-c2ccccc2)cc1,,ClCCl,,BrB(Br)Br,,test
US20070254872A1,COc1ccc2ncc(F)c(CCN3CCN4C(=O)CNCC4C3)c2n1.O=Cc1ccc2c(n1)NC(=O)CS2>>COc1ccc2ncc(F)c(CCN3CCN4C(=O)CN(Cc5ccc6c(n5)NC(=O)CS6)CC4C3)c2n1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04943583,O=C(Cl)OC(Cl)(Cl)Cl.O=C(NNc1ccccc1Br)c1c(F)cccc1F>>O=c1oc(-c2c(F)cccc2F)nn1-c1ccccc1Br,,C1COCCO1,,CCN(CC)CC,,test
US05726205,CC(=O)OC(C)=O.OC1CCC(c2ccccc2)CC1>>CC(=O)OC1CCC(c2ccccc2)CC1,CN(C)c1ccncc1,CCN(CC)CC,,,,test
US20150141400A1,CC(C)(C)[Si](C)(C)Cl.CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1cc(Br)c(CN2CC[C@@H](O)C2)cc1N>>CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1cc(Br)c(CN2CC[C@@H](O[Si](C)(C)C(C)(C)C)C2)cc1N,,ClCCl,,O,c1c[nH]cn1,test
US20020128262A1,CC(=O)c1cc(N)ccc1F.CC(C)(C)OC(=O)OC(=O)[O-]>>CC(=O)c1cc(NC(=O)OC(C)(C)C)ccc1F,,C1CCOC1,,,,test
US20060148858A1,CCCCI.CCOc1cc(OCCCc2cn(-c3ccc(C(F)(F)F)cn3)nc2O)ccc1CCC(=O)OC>>CCCCOc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCOc1ccc(CCC(=O)O)c(OCC)c1,,O,,CN(C)C=O,[H-].[Na+],test
US20120322791A1,NC(N)=S.O=C1CCCC1Cl>>Nc1nc2c(s1)CCC2,,C1COCCO1,,,,test
US20100022813A1,CCc1ccccc1.Cc1ccccc1C>>CCc1ccccc1CC,,c1ccccc1,,,,test
US20150225405A1,CN1CCNCC1.Clc1cc(Br)ccn1>>CN1CCN(c2cc(Br)ccn2)CC1,,CCO,,CCN(CC)CC,,test
US20100216803A1,CC(C)(C)OC(=O)N[C@H]1CCC[C@H]1C(=O)NN.S=C=S>>CC(C)(C)OC(=O)N[C@H]1CCC[C@H]1c1n[nH]c(=S)o1,,CCOCC,O,CCO,[K+].[OH-],test
US20140128371A1,C[C@H]1CN(c2c(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)cc(C(=NO)C(=O)N3CCOCC3)c(F)c2F)C[C@@H](C)O1>>C[C@H]1CN(c2c(CO)cc3c(C(=O)N4CCOCC4)noc3c2F)C[C@@H](C)O1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050009907A1,NO.O=Cc1ccc(-c2ccc(O)cc2)c2ccsc12>>ON=Cc1ccc(-c2ccc(O)cc2)c2ccsc12,,CCOCC,CO,Cl,c1ccncc1,test
US20110150834A1,CCOC(=O)Cn1c(C)ccc1C.II.O=S(=O)(c1ccccc1SSc1ccccc1S(=O)(=O)N1CCCC1)N1CCCC1>>CCOC(=O)Cn1c(C)c(I)c(Sc2ccccc2S(=O)(=O)N2CCCC2)c1C,,CN(C)C=O,O,,,test
US20100311741A1,COC(=O)/C=C/c1ccc(Br)cc1S(=O)(=O)Nc1ccccc1.OB(O)c1ccccc1>>COC(=O)/C=C/c1ccc(-c2ccccc2)cc1S(=O)(=O)Nc1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140323468A1,Brc1cnc2c(c1)CCN2.O=C=NC(=O)C(Cl)(Cl)Cl>>NC(=O)N1CCc2cc(Br)cnc21,,ClCCl,,[K+].[OH-],,test
US20160235734A1,COC(=O)C(=O)c1ccccc1.C[Si](C)(C)N(c1cccc([Mg]Cl)c1)[Si](C)(C)C>>COC(=O)C(O)(c1ccccc1)c1cccc(N)c1,,CN(C)C=O,,C1CCOC1,,test
US05244863,C=C1CN(c2cccc(C(F)(F)F)c2)C(=NC(=O)NCC)S1>>CCNC(=O)N=c1sc(C)cn1-c1cccc(C(F)(F)F)c1,,CO,,C[O-].[Na+],,test
US20110172252A1,ClCc1ccccn1.O[C@H]1CCOC1>>c1ccc(CO[C@H]2CCOC2)nc1,,C1CCOC1,,[H-].[Na+],,test
US20120184542A1,COc1ccc(CN2C(=O)C(F)(F)C2c2ccccc2)cc1.N>>COc1ccc(CNC(c2ccccc2)C(F)(F)C(N)=O)cc1,,CO,,,,test
US20070054884A1,COc1cc(C)ccc1O.N#Cc1ccccc1F>>COc1cc(C)ccc1Oc1ccccc1C#N,,CC(=O)N(C)C,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20040248884A1,CC1(C)NC(=O)N(c2ccc(OC(F)(F)F)cc2)C1=O.COc1ccc2nccc(CCl)c2c1>>COc1ccc2nccc(CN3C(=O)N(c4ccc(OC(F)(F)F)cc4)C(=O)C3(C)C)c2c1,,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US20110166169A1,CC(C)(C)OC(=O)c1ccc(-n2c3ccccc3c3c(-c4ccc(C#N)nc4)cccc32)cc1NCCF>>N#Cc1ccc(-c2cccc3c2c2ccccc2n3-c2ccc(C(=O)O)c(NCCF)c2)cn1,,C1COCCO1,,Cl,,test
US05550134,CC(C)(C)C(=O)Cl.CN1C(=O)CC[C@]2(C)c3ccc(-c4cccc(N)c4)cc3CC[C@@H]12>>CN1C(=O)CC[C@]2(C)c3ccc(-c4cccc(NC(=O)C(C)(C)C)c4)cc3CC[C@@H]12,,ClC(Cl)Cl,,ClCCl,c1ccncc1,test
US20120004270A1,CC(C)(O)[C@@H](N)C(=O)O.CS(C)=O.N#Cc1ccc(F)cc1C(F)(F)F>>CC(C)(C)[C@@H](Nc1ccc(C#N)c(C(F)(F)F)c1)C(=O)O,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110218192A1,CC(=O)c1cc(Br)ccc1O.O=Cc1ccccc1>>O=C1CC(c2ccccc2)Oc2ccc(Br)cc21,,CCO,O,,,test
US20140018393A1,O=C(N(CC1CCNCC1)[C@@H]1C[C@H]1c1ccccc1)C(F)(F)F.O=Cc1ccc(CC(=O)O)cc1>>O=C(O)Cc1ccc(CN2CCC(CN[C@@H]3C[C@H]3c3ccccc3)CC2)cc1,,ClCCCl,,[Na+].[OH-],,test
US20050043368A1,CC(C)(C)[C@H](O)Cn1ccc(C(F)(F)F)n1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)(C)[C@@H](Cn1ccc(C(F)(F)F)n1)OC(=O)Oc1ccc([N+](=O)[O-])cc1,,ClCCCl,,c1ccncc1,O=C([O-])O.[Na+],test
US05346881,Nc1c(F)cc(Cl)c2c1OCCO2.O=C(Cl)OC(Cl)(Cl)Cl>>O=C=Nc1c(F)cc(Cl)c2c1OCCO2,,Cc1ccccc1,,,,test
US20080269211A1,COC(=O)C[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COC(=O)C[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)OC(C)(C)C,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05824691,COC(=O)c1cccc(-n2cccc2/C=C/C(=O)OCc2ccccc2)c1>>COC(=O)c1cccc(-n2cccc2CCC(=O)O)c1,[Pd],CO,,,,test
US05292891,CC1(C)OC(=O)C=C(CC(O)CCl)O1>>O=C1CC(=O)OC(CCl)C1,,CCOC(C)=O,,CO,O=C([O-])[O-].[K+].[K+],test
US20100056511A1,CC(C)(N)c1cccc([N+](=O)[O-])c1.CC(C)C(=O)CBr>>CC(C)C(=O)CNC(C)(C)c1cccc([N+](=O)[O-])c1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US05021420,CC(CCBr)N1c2cccc3cccc(c23)S1(=O)=O.Fc1ccc(N2CCNCC2)cc1>>CC(CCN1CCN(c2ccc(F)cc2)CC1)N1c2cccc3cccc(c23)S1(=O)=O,,Cc1ccccc1,,CCN(CC)CC,,test
US05208247,CCCCCCCCCCCCCCBr.CCN(CC)C(=O)c1ccccc1O>>CCCCCCCCCCCCCCOc1ccccc1C(=O)N(CC)CC,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110021501A1,COC(=O)c1cccc(C2CCN(c3nc4c(c(NC5CCOCC5)n3)S(=O)CC4)CC2)c1>>O=C(O)c1cccc(C2CCN(c3nc4c(c(NC5CCOCC5)n3)S(=O)CC4)CC2)c1,,CO,,Cl,[Na+].[OH-],test
US20070135452A1,Cn1c(=O)[nH]c2ccnc([N+](=O)[O-])c21>>Cn1c(=O)[nH]c2ccnc(N)c21,[Ni],CO,,,,test
US20070072847A1,Cc1cc(C[C@@H](OC(=O)N2CCC(n3nc(-c4ccccc4)[nH]c3=O)CC2)C(=O)N2CCC(C3CCN(Cc4ccccc4)CC3)CC2)cc(C)c1O>>Cc1cc(C[C@@H](OC(=O)N2CCC(n3nc(-c4ccccc4)[nH]c3=O)CC2)C(=O)N2CCC(C3CCNCC3)CC2)cc(C)c1O,[Pd],CO,,[H][H],,test
US20110059043A1,COC(=O)c1cc(Cl)ccc1O.CSCCCl>>COC(=O)c1cc(Cl)ccc1OCCSC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050233988A1,CCc1ccc(CC(C#N)C#N)cc1.NN>>CCc1ccc(Cc2c(N)n[nH]c2N)cc1,,CCO,,O,,test
US04822805,COc1cc(Cl)c([N+](=O)[O-])cc1-c1nc(C)c(-c2cccnc2)[nH]1>>COc1cc(Cl)c(N)cc1-c1nc(C)c(-c2cccnc2)[nH]1,[Pd],CO,,Cl,[H][H],test
US06143764,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.Nc1cc(F)cc(F)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(F)cc(F)c4)cc3)c2cc1OC,,CCN(CC)CC,Cc1ccccc1,O=C([O-])O.[Na+],,test
US20090227640A1,COC(=O)c1cc(F)ccc1OCc1ccccc1Cl>>O=C(O)c1cc(F)ccc1OCc1ccccc1Cl,,CO,,[Na+].[OH-],,test
US20080200475A1,CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(NC(=O)CNC(=O)OCc3ccccc3)nc2s1>>CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(NC(=O)CN)nc2s1,,CC(=O)O,CCOCC,Br,,test
US20150282482A1,CB(O)O.COC(=O)c1cc2cccc(Br)c2s1>>COC(=O)c1cc2cccc(C)c2s1,,O,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US05362725,COC(=O)CBr.OCCN1CCN2c3ccccc3Cc3ccccc3C2C1>>COC(=O)COCCN1CCN2c3ccccc3Cc3ccccc3C2C1,,Cc1ccccc1,,[H-].[Na+],,test
US20070129334A1,CCCn1c(Sc2nc3c(N)ncnc3n2CCOC(C)=O)cc2ccccc21.O=C1CCC(=O)N1I>>CCCn1c(Sc2nc3c(N)ncnc3n2CCOC(C)=O)c(I)c2ccccc21,,C1CCOC1,,CCOC(C)=O,,test
US20080021023A1,COc1cc([N+](=O)[O-])c(OC)cc1C>>COc1cc([N+](=O)[O-])c(O)cc1C,,ClCCl,,ClB(Cl)Cl,,test
US20100292225A1,CN(C(c1cncc(-c2ccc(C#N)c(Cl)c2)c1Cl)C1CC1)S(C)(=O)=O>>CN1C(C2CC2)c2cncc(-c3ccc(C#N)c(Cl)c3)c2CS1(=O)=O,,C1CCOC1,CS(C)=O,CC(C)(C)[O-].[K+],,test
US20050187236A1,CCOC(=O)CCCC1CCN(C(=O)OC(C)(C)C)CC1>>CCOC(=O)CCCC1CCNCC1,,O=C(O)C(F)(F)F,,,,test
US04760179,C=CC(=O)NC(C)(C)C.ON(Cc1ccccc1)Cc1ccccc1>>CC(C)(C)NC(=O)CCON(Cc1ccccc1)Cc1ccccc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US04758383,CC(=O)O[C@@H]1CC2=CC=C3[C@@H]4CC[C@H]([C@H](C)C=C[C@H](C)C(C)C)[C@@]4(C)CC[C@@H]3[C@@]2(C)[C@@H](OC(C)=O)C1>>C=C1/C(=C\C=C2/CCC[C@@]3(C)[C@H]2CC[C@@H]3[C@H](C)/C=C/[C@H](C)C(C)C)C[C@@H](O)C[C@@H]1O,,CCOCC,,,,test
US20110118238A1,CCOc1cc(N2CCC(N(C)C)CC2)ccc1[N+](=O)[O-]>>CCOc1cc(N2CCC(N(C)C)CC2)ccc1N,[Pd],CCO,,,,test
US20080227770A1,COC(=O)CC[C@H](NC(=O)C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2N(CC(C)(C)COC(C)=O)C1=O)C(C)=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COC(=O)CCc1nc(C[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3N(CC(C)(C)COC(C)=O)C2=O)sc1C,,C1CCOC1,,,,test
US20150148313A1,C=C(C#N)c1ccc(NC(=O)OC(C)(C)C)cc1CN(C)C(=O)OC(C)(C)C.C[S+](C)(C)=O>>CN(Cc1cc(NC(=O)OC(C)(C)C)ccc1C1(C#N)CC1)C(=O)OC(C)(C)C,,CS(C)=O,,[H-].[Na+],,test
US20050026964A1,CCOC(=O)c1cn(CCOCCOC)c(=O)cc1Nc1ccc(I)cc1F>>COCCOCCn1cc(C(=O)O)c(Nc2ccc(I)cc2F)cc1=O,,CCO,,[Na+].[OH-],,test
US20070027178A1,Cc1ccc(C(F)(F)F)c(NN)c1.Cl.O=C1CCNCC1>>Cc1ccc(C(F)(F)F)c2[nH]c3c(c12)CNCC3.Cl,,CC(C)O,,O,,test
US20120065202A1,CCN=C=O.C[C@H]1COCCN1c1nc(-c2ccc(N)c(F)c2)nc2c1CN(C)C2>>CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOC[C@@H]4C)n2)CN(C)C3)cc1F,,C1CCOC1,,,,test
US05066660,CN.COC(=O)c1ccc2[nH]cc(C3=CCN(C)CC3)c2c1>>CNC(=O)c1ccc2[nH]cc(C3=CCN(C)CC3)c2c1,,CCO,CO,,,test
US20090182023A1,O=C(CCCCc1ccccc1)Nc1ccc2c(c1O)C(=O)CC2>>O=C1CCc2ccc3nc(CCCCc4ccccc4)oc3c21,,Cc1ccccc1C,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20070276000A1,COc1ccc2c(c1)CC(C)C(Br)(Br)C2=O>>COc1ccc2c(O)c(Br)c(C)cc2c1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US05840917,CCc1ccco1.O=C=O>>CCc1ccc(C(=O)O)o1,,CCOCC,,Cl,[Li]CCCC,test
US04233299,COC(=O)C1=C(O)c2cc(C)ccc2S(=O)(=O)N1C.Cc1cnc(N)s1>>Cc1ccc2c(c1)C(O)=C(C(=O)Nc1ncc(C)s1)N(C)S2(=O)=O,,Cc1ccccc1C,,,,test
US20100280071A1,CO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C)cc(F)c3[N+](=O)[O-])CC2)CC1>>CO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C)ccc3N)CC2)CC1,[Ni],CCO,,NN,O,test
US20060063841A1,CCC(=O)c1cc(Cl)ccc1NS(=O)(=O)C(F)(F)F.NOc1ccc(F)cc1>>CCC(=NOc1ccc(F)cc1)c1cc(Cl)ccc1NS(=O)(=O)C(F)(F)F,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20160090374A1,CC(C)(C)OC(=O)N[C@H]1CCN(c2nc(Cl)nc3ccccc23)C1.CCCBr>>CCCN(C(=O)OC(C)(C)C)[C@H]1CCN(c2nc(Cl)nc3ccccc23)C1,,O,,CN(C)C=O,[H-].[Na+],test
US05389632,CCCc1nc2ccnn2c(O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=P(Cl)(Cl)Cl>>CCCc1nc2ccnn2c(Cl)c1Cc1ccc(-c2ccccc2C#N)cc1,,ClCCl,,,,test
US20020049328A1,C[C@H]1NCc2cc(-c3ccc4c(=O)c(C(=O)O)cn(C5CC5)c4c3OC(F)F)ccc21.O=P(O)(O)O>>C[C@H]1NCc2cc(-c3ccc4c(=O)c(C(=O)O)cn(C5CC5)c4c3OC(F)F)ccc21.O=P(O)(O)O,,O,,CCO,,test
US20100048537A1,CCOC(=O)CCN(Cc1ccco1)C(=O)OCC>>CCOC(=O)N(CCC(=O)O)Cc1ccco1,,CO,,[K+].[OH-],,test
US20100249123A1,CCOC(=O)C(C)(CNC(=O)c1cnc2ccccn12)c1ccc(NC(=O)c2ccc(OC)c(OC)c2)cc1>>COc1ccc(C(=O)Nc2ccc(C(C)(CO)CNC(=O)c3cnc4ccccn34)cc2)cc1OC,,C1CCOC1,,[BH4-].[Li+],,test
US04590192,CCO.O=[N+]([O-])c1cccc2c1C(Cl)=NS2(=O)=O>>CCOC1=NS(=O)(=O)c2cccc([N+](=O)[O-])c21,,ClCCl,,,,test
US20040029911A1,C=CC(=O)OCC.CCOC(=O)c1ccc(COCc2ccccc2)nc1>>CCOC(=O)CCN1CC(C(=O)OCC)CCC1COCc1ccccc1,,CCOC(C)=O,,Cl,,test
US20090286768A1,Clc1ccc([Mg]Br)cc1.O=CC1CCCCO1>>OC(c1ccc(Cl)cc1)C1CCCCO1,,C1CCOC1,,,,test
US05593993,NCCc1ccccc1Cl.S=C(Nc1nc2ccccc2[nH]1)n1ccnc1>>S=C(NCCc1ccccc1Cl)Nc1nc2ccccc2[nH]1,,CN(C)C=O,,CCOC(C)=O,,test
US20130150339A1,O=S(=O)(Nc1nccs1)c1ccc2c(Cl)nccc2c1.c1ccc(C2CCNC2)cc1>>O=S(=O)(Nc1nccs1)c1ccc2c(N3CCC(c4ccccc4)C3)nccc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140256599A1,CCCCCCCCCCCCCCCCN.Cl.N#CN>>CCCCCCCCCCCCCCCCNC(N)=[NH2+].[Cl-],,CCCCO,,,,test
US20120101257A1,COC(=O)[C@H](Cc1c[nH]c2ccccc12)NCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OCc1ccccc1>>COC(=O)[C@H](Cc1c[nH]c2ccccc12)N1CC[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C1=O,,Cc1ccccc1,,,,test
US20160184305A1,COc1cc2cnc(C)cc2cc1Br.OO>>COc1cc2c[n+]([O-])c(C)cc2cc1Br,O=[Mn]=O,ClCCl,,,,test
US20040034049A1,CC(C)c1ccc(C2c3ccc(O)cc3OC2(C)C)cc1.COc1ccc(CCl)cc1>>COc1ccc(COc2ccc3c(c2)OC(C)(C)C3c2ccc(C(C)C)cc2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20160009726A1,CC1(C)OB(c2c(F)cc(C=O)cc2F)OC1(C)C>>CC1(C)OB(c2c(F)cc(CO)cc2F)OC1(C)C,,CCOC(C)=O,CO,[BH4-].[Na+],,test
US20140088167A1,CCN.O=C(NC1CC1)c1cc([N+](=O)[O-])c(F)cc1Cl>>CCNc1cc(Cl)c(C(=O)NC2CC2)cc1[N+](=O)[O-],,C1CCOC1,,,,test
US20010021718A1,CC(C)(C)OC(=O)C[C@@H](CCCC1CCCCC1)c1nc(C(=O)NCc2ccccc2)no1>>O=C(O)C[C@@H](CCCC1CCCCC1)c1nc(C(=O)NCc2ccccc2)no1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05126344,CCc1cc(OCc2ccc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc2)c2nc(OC)ccc2n1.Cl>>CCc1cc(OCc2ccc(-c3ccccc3-c3nnn[nH]3)cc2)c2nc(OC)ccc2n1.Cl,,CO,,,,test
US20130109661A1,CCOC(CCl)OCC.COC(=O)c1cccc(-c2cc(Br)c(N)nn2)c1>>COC(=O)c1cccc(-c2cc(Br)c3nccn3n2)c1,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040110787A1,CNCC(O)c1ccccn1.COc1ccc2cc([C@H](C)C(=O)O)ccc2c1>>CNC[C@@H](O)c1ccccn1.COc1ccc2cc([C@H](C)C(=O)O)ccc2c1,,CCO,,,,test
US06040309,CCOC(=O)c1sc2cc(CBr)ccc2c1Cl.c1c[nH]cn1>>CCOC(=O)c1sc2cc(Cn3ccnc3)ccc2c1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20050288273A1,CCC(=O)C1CCCc2cc(N3C[C@H](CNC(C)=O)OC3=O)ccc2C1=O.NN>>CCc1n[nH]c2c1CCCc1cc(N3C[C@H](CNC(C)=O)OC3=O)ccc1-2,,CCO,,Cl,O=C([O-])O.[Na+],test
US20110294776A1,CC(C)(C)OC(=O)N1CCC(c2cccc(-c3cc(-c4ccc5cn(Cc6ccccc6)nc5c4)c4c(N)ncnn34)c2)CC1>>Nc1ncnn2c(-c3cccc(C4CCNCC4)c3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12,,C1COCCO1,Cl,CCOC(C)=O,,test
US05204360,CSC(=C[N+](=O)[O-])SC.Cn1cc(CNCCCN)cn1>>Cn1cc(CN2CCCNC2=C[N+](=O)[O-])cn1,,CCO,,,,test
US20120226047A1,CCOc1ccc(C=O)c(OC)c1.[NH4+]>>CCOc1ccc(CN)c(OC)c1,,CO,,[BH3-]C#N.[Na+],,test
US20020128255A1,BrP(Br)Br.CCCN(CCC)C(=O)c1cc(CO)cc(C(=O)OCC)c1>>CCCN(CCC)C(=O)c1cc(CBr)cc(C(=O)OCC)c1,,ClCCl,,,,test
US20050176767A1,COC(=O)c1nc(C2CCCO2)cc(NC(C)=O)c1O.NCc1ccc(F)cc1>>CC(=O)Nc1cc(C2CCCO2)nc(C(=O)NCc2ccc(F)cc2)c1O,,Cc1ccccc1,,,,test
US20090286812A1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.N#Cc1ccc(O)cc1>>CC(C)(C)OC(=O)N1CCC(n2ncc3c(Oc4ccc(C#N)cc4)ncnc32)CC1,,CC#N,,,,test
US20100298324A1,COC(=O)c1ccc(C(=O)NCc2ccc(Cl)cc2)cc1N=C=S.COC(=O)c1ccc(N)nc1>>O=C(O)c1ccc(-n2c(=S)[nH]c3cc(C(=O)NCc4ccc(Cl)cc4)ccc3c2=O)nc1,,CN(C)C=O,CS(C)=O,[Na+].[OH-],,test
US20060276533A1,CI.COC(=O)c1sc(C2=CCCCC2)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)[C@@H]1CC[C@@H](O)CC1>>COC(=O)c1sc(C2=CCCCC2)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)[C@@H]1CC[C@@H](OC)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20030166639A1,CN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3ccnc(COC4CCCCO4)c3)c2)cc1C(F)(F)F>>CN(C)c1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3ccnc(CO)c3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020045758A1,CS(=O)c1c(C=O)nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1N.NO>>CS(=O)c1c(C=NO)nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1N,,CO,,Cl,c1ccncc1,test
US20150018363A1,Cn1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cc21.OCc1cc(Cl)cs1>>Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4cc(Cl)cs4)cc3=O)cc21,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20160083343A1,O=C(Cl)c1ccccc1.OC[C@@H]1CCCCN1>>O=C(c1ccccc1)N1CCCC[C@H]1CO,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20070208166A1,CCOCCCNC(=O)c1ccc(C(=O)NCC2COc3ccccc3O2)cc1N.S=C(Cl)Cl>>CCOCCCn1c(=S)[nH]c2cc(C(=O)NCC3COc4ccccc4O3)ccc2c1=O,,ClCCl,,,,test
US20100021423A1,COc1ncccc1-c1cc(NC(=O)c2ccc(N)cc2)c(OC)c(C(C)(C)C)c1.CS(=O)(=O)Cl>>COc1ncccc1-c1cc(NC(=O)c2ccc(NS(C)(=O)=O)cc2)c(OC)c(C(C)(C)C)c1,,CCOC(C)=O,c1ccncc1,,,test
US20110092561A1,CCOC(=O)Cc1ccc(N2Cc3c(c(OCC)c4ccccc4c3OC(F)F)C2=O)c(F)c1>>CCOc1c2c(c(OC(F)F)c3ccccc13)CN(c1ccc(CC(=O)O)cc1F)C2=O,,O,,CC(=O)O,Cl,test
US20040063680A1,CC(C)S(=O)(=O)NCC(C)(F)c1ccc(-c2ccc(C(=O)O)cc2)cc1.CN>>CNC(=O)c1ccc(-c2ccc(C(C)(F)CNS(=O)(=O)C(C)C)cc2)cc1,CN(C)C=O,ClCCl,O,C1CCOC1,O=C(Cl)C(=O)Cl,test
US20020065308A1,Cl[Mg]Cc1ccccc1.O=C1CCC2CCC(=O)N12>>O=C(CCC1CCC(=O)N1)Cc1ccccc1,,ClCCl,,,,test
US20070298352A1,O=C(OCCC(F)(F)C(F)(F)S(=O)(=O)[O-])c1ccccc1.c1ccc([S+](c2ccccc2)c2ccccc2)cc1>>O=C(OCCC(F)(F)C(F)(F)S(=O)(=O)[O-])c1ccccc1.c1ccc([S+](c2ccccc2)c2ccccc2)cc1,,ClCCl,,[Cl-].[Na+],,test
US20110028390A1,CC(=O)c1cc(Br)ccc1N.O=C1CCC(=O)N1Cl>>CC(=O)c1cc(Br)cc(Cl)c1N,,ClCCl,,,,test
US20150158847A1,COc1cc(Cn2cnc3cc(I)cnc32)ccc1O.COc1ccc(C(C)Cl)cn1>>COc1ccc(C(C)Oc2ccc(Cn3cnc4cc(I)cnc43)cc2OC)cn1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060128685A1,CCOC(=O)C(=O)CC(=O)c1ccccc1.COc1ccc(NN)nc1>>CCOC(=O)c1cc(-c2ccccc2)n(-c2ccc(OC)cn2)n1,,CCO,,,,test
US05057614,CSCCCn1cc(C2=C(c3cn(C)c4ccccc34)C(=O)NC2=O)c2ccccc21.O=C(OO)c1cccc(Cl)c1>>Cn1cc(C2=C(c3cn(CCCS(C)=O)c4ccccc34)C(=O)NC2=O)c2ccccc21,,ClCCl,,,,test
US20120309796A1,CC(C)(C)OC(=O)COc1cccc2c1CCCCC2NS(=O)(=O)c1ccc(Br)cn1.Cc1cc(B(O)O)cc(C(C)(C)C)c1>>Cc1cc(-c2ccc(S(=O)(=O)NC3CCCCc4c(OCC(=O)OC(C)(C)C)cccc43)nc2)cc(C(C)(C)C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20160264552A1,CC(C)(C)OC(=O)Nc1ccc(C(=O)N2CC[C@@H](Nc3ncc(Cl)c(-c4cn(S(=O)(=O)c5ccccc5)c5ccccc45)n3)C2)cc1>>Nc1ccc(C(=O)N2CC[C@@H](Nc3ncc(Cl)c(-c4cn(S(=O)(=O)c5ccccc5)c5ccccc45)n3)C2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150126485A1,O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(Cl)c(-c2ccnn2C2CCCCO2)c1>>O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(Cl)c(-c2ccn[nH]2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150025274A1,COC[C@@H](N)C(=O)NCc1ccccc1.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>COC[C@@H](NC(C)=O)C(=O)NCc1ccccc1,,O,,[NH4+].[OH-],,test
US06350749B1,Cl.N=C(N)NN.NC(=O)c1coc2c1C(=O)CC(c1ccccc1)C2>>Cl.N=C(N)N/N=C1\CC(c2ccccc2)Cc2occ(C(N)=O)c21,,CCO,,Cl,,test
US20090221583A1,O=C(OCc1ccccc1)C1CCN(CCCc2ccccc2)CC1>>O=C(O)C1CCN(CCCc2ccccc2)CC1,[Pd],CO,,,,test
US20070093509A1,CCOC(=O)c1sc(Br)cc1N.COC(OC)N(C)C>>COC(=O)c1sc(Br)cc1N=CN(C)C,,CCO,,,,test
US04906621,CCOC(=O)[C@H]1[C@@H](CCOCOCc2ccccc2)CCN1C(=O)OCC>>CCOC(=O)[C@H]1[C@H](CCOCOCc2ccccc2)CCN1C(=O)OCC,,CCO,,Cl,[Li]CCCC,test
US20040138255A1,CCNc1ccc(S(=O)(=O)C(F)(F)F)cc1N.COC(=O)c1ccc(C=O)cc1>>CCn1c(-c2ccc(C(=O)OC)cc2)nc2cc(S(=O)(=O)C(F)(F)F)ccc21,,CCCCCO,,,,test
US04604390,CCN(CC)CCn1nc2c3c(c(N)ccc31)Sc1ccc(O)cc1-2.O=C1NC(=O)c2c(CCBr)cccc21>>Br.CCN(CC)CCn1nc2c3c(c(NCCN4C(=O)c5ccccc5C4=O)ccc31)Sc1ccc(O)cc1-2,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,,test
US20060258671A1,Nc1ccc(I)cc1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(Nc1ccc(I)cc1)c1ccccc1,,CC#N,,c1ccncc1,,test
US20080274892A1,CC1(C)OC(=O)NC1=O.O=[N+]([O-])c1ccccc1CCl>>CC1(C)OC(=O)N(Cc2ccccc2[N+](=O)[O-])C1=O,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20040192728A1,CCCCC[Mg]Br.COC(=O)c1cccnc1.O=C(Cl)Oc1ccccc1>>CCCCCC1C=CC(C(=O)OC)=CN1C(=O)Oc1ccccc1,,C1CCOC1,,,,test
US20070207175A1,CCCCOc1ccc(C(=O)N(C)Cc2cccc(-c3ccc(CCC(=O)OC)cc3OCCCC)c2)cc1>>CCCCOc1ccc(C(=O)N(C)Cc2cccc(-c3ccc(CCC(=O)O)cc3OCCCC)c2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20110092501A1,C[Si](C)(C)C#N.Nc1ccc2[nH]cnc2c1.O=C(n1ccnc1)n1ccnc1.O=Cc1ccc(N2CCCCC2)cc1>>O=C1NCC(c2ccc(N3CCCCC3)cc2)N1c1ccc2[nH]cnc2c1,[Pd],,,,,test
US20110105509A1,COC(=O)Cn1c(C)c(Cc2ccc(=O)[nH]c2)c2ccccc21.Fc1ccc(CBr)c(F)c1>>COC(=O)Cn1c(C)c(Cc2ccc(=O)n(Cc3ccc(F)cc3F)c2)c2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05955607,CCS(=O)(=O)N(CCCCC(=O)OC)C1CC(C)(C)Oc2ccc(C)cc21.N>>CCS(=O)(=O)N(CCCCC(N)=O)C1CC(C)(C)Oc2ccc(C)cc21,,CO,,,,test
US04115407,NC1CCOc2ccccc21.O=Cc1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(C=NC2CCOc3ccccc32)c1,,CCO,,,,test
US20080255160A1,CNc1cc(=O)[nH]cn1.COc1ccc(CCl)cc1>>CNc1cc(=O)n(Cc2ccc(OC)cc2)cn1,,CN(C)C=O,,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US20150087658A1,Cc1cccc(Cl)c1C(=O)O.NC1CC1>>Cc1cccc(Cl)c1C(=O)NC1CC1,,Cc1ccccc1,,CCN(CC)CC,O=S(Cl)Cl,test
US04927838,CCC(CC)n1c(C=O)cc2ccc(OC)cc21.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.ClCCl>>CCCCCc1c(/C=C/C(=O)OC)n(C)c2cc(OC)ccc12,,ClCCl,,,,test
US20160168158A1,COc1ccc(Cn2nnc3c(N4CCC(F)(F)C4)nc(NC(C)(C)C)nc32)cc1>>CC(C)(C)Nc1nc(N2CCC(F)(F)C2)c2nn[nH]c2n1,[Pd],CO,,,,test
US20120094997A1,CC(C)N.COC(=O)c1ccc(C(=O)O)c([N+](=O)[O-])c1>>COC(=O)c1ccc(C(=O)NC(C)C)c([N+](=O)[O-])c1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04108668,COc1ccc2nccc(C)c2c1.NC(=O)CCl>>COc1ccc2c(c1)c(C)cc[n+]2CC(N)=O.[Cl-],,C1COCCO1,,,,test
US05767142,Nc1ccccc1[N+](=O)[O-].O=C1C(Br)=CC(Br)(Br)C=C1Br>>Nc1ccc(Br)cc1[N+](=O)[O-],,ClCCl,,,,test
US20140275172A1,CC(=O)O.Nc1c(Br)cc(OC(F)(F)F)cc1Br>>CC(=O)Nc1c(Br)cc(OC(F)(F)F)cc1Br,,CC(=O)O,,CC(=O)OC(C)=O,,test
US05744465,CC(O)C1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(SC3COC(COP(=O)(O)OCC[n+]4ccccc4)C3)C(C)C12.[OH-]>>CC(O)C1C(=O)N2C(C(=O)O)=C(SC3COC(COP(=O)(O)OCC[n+]4ccccc4)C3)C(C)C12.[OH-],[Pd],C1COCCO1,,O,O=C([O-])O.[Na+],test
US05952362,O=[N+]([O-])c1cccc(O)c1.OCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>O=[N+]([O-])c1cccc(OCc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)c1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100292196A1,FC(F)(F)CI.c1nc2[nH]ncc2c(NC2CCOCC2)c1C1=NOC2(CCC2)C1>>FC(F)(F)Cn1ncc2c(NC3CCOCC3)c(C3=NOC4(CCC4)C3)cnc21,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04269980,CCOC(OCC)OC(C)=O.NNc1ncncc1-c1ccc(Cl)cc1>>Clc1ccc(-c2cncn3cnnc23)cc1,,CCCCCC,,,,test
US20130065876A1,COC(=O)c1cnc(OCC(F)(F)F)c(-c2ccc(Cl)c(F)c2)c1.NN>>NNC(=O)c1cnc(OCC(F)(F)F)c(-c2ccc(Cl)c(F)c2)c1,,CCO,,O,O=C([O-])[O-].[Na+].[Na+],test
US20120208839A1,CNc1nc(OCC(F)F)c(C(=O)N[C@@H]2CC[C@@H](C(F)(F)F)CC2)cc1NC(=S)Nc1cc(CNC(=O)C(C)(C)C)ccc1Cl>>Cn1c(Nc2cc(CNC(=O)C(C)(C)C)ccc2Cl)nc2cc(C(=O)N[C@@H]3CC[C@@H](C(F)(F)F)CC3)c(OCC(F)F)nc21,,CC#N,,CC(C)N=C=NC(C)C,,test
US20060111375A1,CCOC(=O)c1cc(-n2cccc2)ccc1O.COc1cc2nccc(Cl)c2cc1OC>>CCOC(=O)c1cc(-n2cccc2)ccc1Oc1ccnc2cc(OC)c(OC)cc12,CN(C)c1ccncc1,Clc1ccccc1Cl,,,,test
US20130184254A1,FC1(F)CN(c2ncncc2I)C1.OB(O)c1ccnc2c1cnn2-c1ccc(F)cc1F>>Fc1ccc(-n2ncc3c(-c4cncnc4N4CC(F)(F)C4)ccnc32)c(F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20140309193A1,CCOC(=O)c1c(OCc2ccccc2)c(OCc2ccccc2)c(-c2ccccn2)n1-c1ccc(OC)cc1>>CCOC(=O)c1c(O)c(O)c(-c2ccccn2)n1-c1ccc(OC)cc1,[Pd],C1CCOC1,CO,,,test
US06383986B1,O=[N+]([O-])c1c(O)c(Cl)cc(F)c1-c1ncc(C(F)(F)F)cc1Cl>>Nc1c(O)c(Cl)cc(F)c1-c1ncc(C(F)(F)F)cc1Cl,[Fe],CC(=O)O,CO,,,test
US06492368B1,CC(=O)O.Cc1nc(-c2ccc(C(=O)N3CCN(S(=O)(=O)c4ccc5cc(Cl)ccc5c4)CC3)cc2)no1>>CC(=O)[O-].N=C(N)c1ccc(C(=O)N2CCN(S(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC2)cc1,[Ni],CO,,,,test
US20060004043A1,CCOC(=O)CNC(C)(C)C.NN>>CC(C)(C)NCC(=O)NN,,CCO,,,,test
US20150038488A1,CC1(C)OC(=O)Nc2cc(Br)ccc21.CI>>CN1C(=O)OC(C)(C)c2ccc(Br)cc21,,C1CCOC1,CN(C)C=O,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20080096860A1,CC(C)(C)N.O=C(N1CCc2ccc(S(=O)(=O)Cl)cc2C1)C(F)(F)F>>CC(C)(C)NS(=O)(=O)c1ccc2c(c1)CN(C(=O)C(F)(F)F)CC2,,ClCCl,,,,test
US04640913,CCCCCCCCCCCCCCCCCCOCC(COC1CCCCO1)NC(C)=O>>CCCCCCCCCCCCCCCCCCOCC(CO)NC(C)=O,,CO,Cl,,,test
US20050288367A1,CCC(Oc1ccc(O)cc1)C(=O)NC.N#Cc1ccc(CBr)cc1>>CCC(Oc1ccc(OCc2ccc(C#N)cc2)cc1)C(=O)NC,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04877802,BrCCBr.Oc1c(Cl)cc(Cl)cc1Cl>>Clc1cc(Cl)c(OCCBr)c(Cl)c1,,CCO,O,[Na+].[OH-],,test
US20130065900A1,COc1cc(CN(Cc2ccccc2)C(=O)OC(C)(C)C)ccc1N.N#Cc1cnc(NC(=O)Oc2ccccc2)cn1>>COc1cc(CN(Cc2ccccc2)C(=O)OC(C)(C)C)ccc1NC(=O)Nc1cnc(C#N)cn1,,CN(C)C=O,,,,test
US20050153959A1,C1CCNCC1.Cc1cc(CC(OC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)c2cc(C(=O)O)ccn2)cc2cn(COCC[Si](C)(C)C)nc12>>Cc1cc(CC(OC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)c2cc(C(=O)N3CCCCC3)ccn2)cc2cn[nH]c12,,ClCCl,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20020193389A1,C1COCCN1.N#Cc1ccccc1F>>N#Cc1ccccc1N1CCOCC1,,CC#N,,,,test
US20140275531A1,C=O.Nc1ncn(Cc2cnc(OC(F)F)c(-c3cccc(Cl)c3)c2)n1>>CNc1ncn(Cc2cnc(OC(F)F)c(-c3cccc(Cl)c3)c2)n1,CC(=O)O,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20120228583A1,Cc1cccc(Nc2ncc(C)cc2[N+](=O)[O-])c1>>Cc1cccc(Nc2ncc(C)cc2N)c1,[Pd],C1CCOC1,CCO,,,test
US20150239900A1,CC1(C)C(=O)N(Br)C(=O)N1Br.Cc1c([N+](=O)[O-])cccc1[N+](=O)[O-]>>Cc1c([N+](=O)[O-])cc(Br)cc1[N+](=O)[O-],,O=S(=O)(O)O,,,,test
US20100179149A1,CC(C)(C)OC(=O)c1ccc(-c2ccc(=O)[nH]n2)cc1.CCOC(=O)Nc1cccc(CO)c1>>CCOC(=O)Nc1cccc(Cn2nc(-c3ccc(O)cc3)ccc2=O)c1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120264749A1,C=C(C)CO.COC(=O)c1ccc(O)c(OC)c1>>C=C(C)COc1ccc(C(=O)OC)cc1OC,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150065505A1,CC(C)(C)[S@@](=O)N[C@H]1CCCc2c(OCC(F)(F)F)cccc21>>N[C@H]1CCCc2c(OCC(F)(F)F)cccc21,,C1COCCO1,ClCCl,Cl,,test
US20160046618A1,COC(C[C@](C)(N)c1cccc(F)c1F)OC.O=C(N=C=S)c1ccccc1>>C[C@@]1(c2cccc(F)c2F)C=CSC(N)=N1,,CO,ClCCl,O=S(=O)(O)O,[Na+].[OH-],test
US20080312307A1,CCOC(=O)c1c(Nc2ccc(Br)cc2F)[nH]c2c1CCCC2=O.COS(=O)(=O)OC>>CCOC(=O)c1c2c(n(C)c1Nc1ccc(Br)cc1F)C(=O)CCC2,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150133437A1,O=C(Nc1ccc2cccnc2n1)c1c(F)cccc1F>>O=C(Nc1ccc2c(n1)NCCC2)c1c(F)cccc1F,[Pd],CCO,,Cl,,test
US20160211456A1,Brc1ccc2c(c1)-c1cc(Br)ccc1C21c2ccccc2-c2ccccc21.OB(O)c1ccccc1-c1ccccc1>>Brc1ccc2c(c1)-c1cc(-c3ccccc3-c3ccccc3)ccc1C21c2ccccc2-c2ccccc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20110287937A1,Cn1c(=O)c(C(=O)O)cc2ccc(C(F)(F)F)nc21.O=C(Cl)C(=O)Cl>>Cn1c(=O)c(C(=O)Cl)cc2ccc(C(F)(F)F)nc21,,ClCCl,,CN(C)C=O,,test
US05521179,CC(C)(C)OC(=O)CBr.O=C(Nc1ccc(CCc2ccccc2)[nH]c1=O)OCc1ccccc1>>CC(C)(C)OC(=O)Cn1c(CCc2ccccc2)ccc(NC(=O)OCc2ccccc2)c1=O,,CN(C)C=O,O,[H-].[Na+],,test
US20120046269A1,COc1ccc(C(=O)Cl)cc1F.C[C@@H](Nc1ncnc2c(C(N)=O)cccc12)c1cccc(N)c1>>COc1ccc(C(=O)Nc2cccc([C@@H](C)Nc3ncnc4c(C(N)=O)cccc34)c2)cc1F,,c1ccncc1,,O,,test
US20120157430A1,COc1c(C(C)=O)cc(Cl)c(C)c1N.O=C(Cl)CCCCl>>COc1c(C(C)=O)cc(Cl)c(C)c1N1CCCC1=O,CN(C)c1ccncc1,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US05534529,CC(C)(C)[Si](C)(C)OCCCC1CCCCC1OCc1ccccc1.CC(C)(C)c1ccc(CCC(CC2CCCCC2)OC(=O)c2ccccc2)cc1N>>CC(C)(C)[Si](C)(C)O[C@H](CO)CC1CCCCC1,[Pd],,,CCO,[H][H],test
US05824802,CC1CCCNC1.CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1F>>CC1CCCN(c2c(S(C)(=O)=O)ccc(C(=O)O)c2Cl)C1,,Cl,,,,test
US20100056568A1,N[C@H]1CC[C@H](O)CC1.O=C1OC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1[C@@H]1CC[C@@H](O)CC1,,ClCCl,,CCCCN(CCCC)CCCC,,test
US20140296067A1,CC(N)C1(c2ncc(C(F)(F)F)cc2Cl)CC1.O=C(Cl)c1c(F)cccc1F>>CC(NC(=O)c1c(F)cccc1F)C1(c2ncc(C(F)(F)F)cc2Cl)CC1,,ClCCl,,CCN(CC)CC,O,test
US20020147214A1,Cc1nn(Cc2ccccc2)c2ccc([N+](=O)[O-])cc12>>Cc1nn(Cc2ccccc2)c2ccc(N)cc12,[Pt],C1CCOC1,,[H][H],,test
US20100069384A1,CCOc1ccc2c(c1)C(C)(c1ccccc1Cl)C(=O)N2.COc1cc([N+](=O)[O-])ccc1S(=O)(=O)Cl>>CCOc1ccc2c(c1)C(C)(c1ccccc1Cl)C(=O)N2S(=O)(=O)c1ccc([N+](=O)[O-])cc1OC,,C1CCOC1,,O,CC(C)(C)[O-].[K+],test
US20100190852A1,COC(=O)c1cc(CO)cc(C(=O)OC)c1>>COC(=O)c1cc(C=O)cc(C(=O)OC)c1,O=[Mn]=O,ClCCl,,,,test
US07319104B2,CCOC(=O)C(C)(C)Oc1ccc(CCN(Cc2ccc(C(F)(F)F)cc2)c2ccc([N+](=O)[O-])cn2)cc1>>CCOC(=O)C(C)(C)Oc1ccc(CCN(Cc2ccc(C(F)(F)F)cc2)c2ccc(N)cn2)cc1,[Pd],CO,,,,test
US20090233918A1,Cc1ccc(S(=O)(=O)Cl)cc1.ON=C1CCOc2ccccc21>>O=C1CCOc2ccccc21,,c1ccncc1,,,,test
US05648354,CC(C)(C)[Si](C)(C)OCC1=CC=C(COc2ccccc2CF)SS1>>OCC1=CC=C(COc2ccccc2F)SS1,,C1CCOC1,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04292429,CCOC(=O)c1ccc(NC(=O)NCCN2CCN=C2c2ccccc2Cl)cc1.Cl>>Cl.O=C(NCCN1CCN=C1c1ccccc1Cl)Nc1ccc(C(=O)O)cc1,,Cl,,[Na+].[OH-],,test
US20080085886A1,CCOC(=O)CO.CCOC(=O)c1cncc(F)c1Cl>>CCOC(=O)c1oc2c(F)cncc2c1O,,CN(C)C=O,,[H-].[Na+],,test
US04698340,CCOC(=O)CC(=O)c1ccc([N+](=O)[O-])cc1.COC(OC)N(C)C>>CCOC(=O)C(=CN(C)C)C(=O)c1ccc([N+](=O)[O-])cc1,,c1ccccc1,,,,test
US20020147212A1,C[Si](C)(C)C=[N+]=[N-].c1ccc(CN[C@@H]2CC[C@H]3[C@H](c4nnn[nH]4)C[C@]2(c2ccccc2)N3Cc2ccccc2)cc1>>Cn1nnc([C@@H]2C[C@@]3(c4ccccc4)[C@H](NCc4ccccc4)CC[C@@H]2N3Cc2ccccc2)n1,,CO,Cc1ccccc1,CCCCCC,,test
US20060094733A1,CCOC(=O)C1CCCN(c2nc3c(c(=O)n(C)c(=O)n3C)n2Cc2c(F)cccc2Cl)C1>>Cn1c(=O)c2c(nc(N3CCCC(C(=O)O)C3)n2Cc2c(F)cccc2Cl)n(C)c1=O,,C1CCOC1,O,[Li+].[OH-],,test
US20120184542A1,CC(C)(C)OC(=O)NCC(N)c1cccc(Cl)c1.COc1ncc2cc(C(=O)Nc3cc(C(=O)O)ccc3Cl)c(=O)[nH]c2n1>>COc1ncc2cc(C(=O)Nc3cc(C(=O)NC(CNC(=O)OC(C)(C)C)c4cccc(Cl)c4)ccc3Cl)c(=O)[nH]c2n1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120088767A1,COC(=O)c1cc(N2CCOCC2)cc2c1nc(Cl)n2Cc1cccc(C(F)(F)F)c1C>>Cc1c(Cn2c(Cl)nc3c(C(=O)O)cc(N4CCOCC4)cc32)cccc1C(F)(F)F,,C1CCOC1,,[Li+].[OH-],,test
US06380387B1,COC(=O)[C@H](Cc1ccc(-c2cn(C)c(=O)n(C)c2=O)c(C)c1)NC(=O)OCc1ccccc1>>COC(=O)[C@@H](N)Cc1ccc(-c2cn(C)c(=O)n(C)c2=O)c(C)c1,[Pd],CCO,,C1=CCCCC1,,test
US20100197679A1,[N-]=[N+]=NCc1cc2c(cn1)OCCO2>>NCc1cc2c(cn1)OCCO2,[Pd],CO,,[H][H],,test
US20060264631A1,CC(C)(C)c1ccc(C(=O)Cl)cc1.Nc1c(Br)cccc1Br>>CC(C)(C)c1ccc(C(=O)Nc2c(Br)cccc2Br)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20100063066A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1cccc2[nH]nc(Cl)c12>>CC(C)(C)OC(=O)n1nc(Cl)c2c([N+](=O)[O-])cccc21,,ClCCl,,CCN(CC)CC,,test
US20100105682A1,CC(C)(C)N.O=C(O)[C@@H]1C[C@H]1C(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1>>CC(C)(C)NC(=O)[C@@H]1C[C@H]1C(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20110077252A1,CCOC(=O)C(Cc1ccccc1)C(C)=O.N=C(N)c1ccc(N)cn1>>Cc1nc(-c2ccc(N)cn2)nc(O)c1Cc1ccccc1,,CCO,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090306136A1,O=S(=O)(Cl)c1cccc(C(F)(F)F)c1.O=S(=O)(c1cccc(C(F)(F)F)c1)N(C1CC1)C1CCN(Cc2ccccc2)CC1.c1ccc(CN2CCC(NC3CC3)CC2)cc1>>O=S(=O)(c1cccc(C(F)(F)F)c1)N(C1CC1)C1CCN(Cc2ccccc2)CC1.O=S(=O)(c1cccc(C(F)(F)F)c1)N(C1CCNCC1)C1CC1,,ClCCl,,CCN(CC)CC,O=C([O-])[O-].[K+].[K+],test
US20110275608A1,CC(C)(C)OC(=O)N1CCC(CCC(=O)c2ccccc2NCCCNC(=O)OCc2ccccc2)CC1.COC(=O)C(=O)Cl>>COC(=O)C(=O)N(CCCNC(=O)OCc1ccccc1)c1ccccc1C(=O)CCC1CCN(C(=O)OC(C)(C)C)CC1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US04900841,CCCCCCCNCC.CS(=O)(=O)Nc1ccc(C(=O)N2CC2)cc1.O=P(O)(O)O>>CCCCCCCN(CC)CCNC(=O)c1ccc(NS(C)(=O)=O)cc1.O=P(O)(O)O,,CC#N,CO,[NH4+].[OH-],,test
US20100305052A1,CCOS(=O)(=O)C(F)(F)F.COc1cc(C#N)ccc1C1C(C#N)=C(C)Nc2cc[nH]c(=O)c21>>CCOc1nccc2c1C(c1ccc(C#N)cc1OC)C(C#N)=C(C)N2,,C1CCOC1,,CO,,test
US20070244159A1,CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)ccc2n1CC(=O)C(=O)O>>CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)ccc2n1CC(O)C(=O)O,,CO,,[BH4-].[Na+],,test
US20070043043A1,COC(=O)C=Cc1ccc2c(c1)nc(CC(C)c1ccccc1)n2CCCO.NO>>CC(Cc1nc2cc(C=CC(=O)NO)ccc2n1CCCO)c1ccccc1,,CO,,Cl,C[O-].[Na+],test
US20140073651A1,CO.Clc1cnnc(Cl)c1>>COc1cnnc(Cl)c1,,CO,,C[O-].[Na+],,test
US20090131423A1,C=Cc1cnc(OC)cc1C(O)c1cc(Cl)cnc1Cl>>C=Cc1cnc(OC)cc1C(=O)c1cc(Cl)cnc1Cl,O=[Mn]=O,ClCCl,,,,test
US20050197350A1,CCOC(=O)Cl.Nc1ccc(F)c(F)c1>>CCOC(=O)Nc1ccc(F)c(F)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20150056141A1,CCOC(=O)c1c(NC(C)=O)sc2c(OCCN(CC)CC)c(Br)ccc12.[N-]=[N+]=NCc1cc(N=[N+]=[N-])cc(B(O)O)c1>>CCOC(=O)c1c(NC(C)=O)sc2c(OCCN(CC)CC)c(-c3cc(CN=[N+]=[N-])cc(N=[N+]=[N-])c3)ccc12,,CC#N,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20020052378A1,CCOC(=O)C(CC(C)C)C(=O)CBr.NC(=S)c1ccccc1>>CCOC(=O)C(CC(C)C)c1csc(-c2ccccc2)n1,,CCO,,,,test
US20090093497A1,O=C(Nc1ccc(C2CCNCC2)cc1)c1nc(-c2ccccc2)oc1C(F)(F)F.O=C(O)Cc1nnn[nH]1>>O=C(Nc1ccc(C2CCN(C(=O)Cc3nnn[nH]3)CC2)cc1)c1nc(-c2ccccc2)oc1C(F)(F)F,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US08629147B2,Cc1cccc([N+](=O)[O-])c1N.ClI>>Cc1cc(I)cc([N+](=O)[O-])c1N,,CC(=O)O,,O,CC(=O)[O-].[Na+],test
US06228853B1,O=C(Cl)OCc1ccccc1.O=C1NCCC1NC(=O)C(F)(F)F>>O=C(OCc1ccccc1)N1CCC(NC(=O)C(F)(F)F)C1=O,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20030134808A1,CC(=O)OC[C@]1(COCc2ccccc2)O[C@@H](n2cc(C)c(=O)[nH]c2=O)[C@H](OC(C)=O)[C@@H]1OCc1ccccc1>>Cc1cn([C@@H]2O[C@](CO)(COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H]2O)c(=O)[nH]c1=O,,CO,,Cl,C[O-].[Na+],test
US20160184318A1,Cc1cnc(CC2CCNCC2)o1.Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)O)n1>>Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)N2CCC(Cc3ncc(C)o3)CC2)n1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070037888A1,COCCN.Cc1cc(Nc2cc(Cl)nc(N3CCCC3c3cc(-c4ccccn4)no3)n2)n[nH]1>>COCCNc1cc(Nc2cc(C)[nH]n2)nc(N2CCCC2c2cc(-c3ccccn3)no2)n1,,C1COCCO1,,,,test
US20090197959A1,CCN.O=C(Cl)OCc1ccccc1>>CCNC(=O)OCc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100029650A1,CC(Oc1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1)C1CCN(c2ncc(F)cn2)CC1>>C[C@@H](Oc1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1)C1CCN(c2ncc(F)cn2)CC1,,CO,,O=C=O,,test
US20080188531A1,CC(=O)Nc1nc(C)c(-c2csc(C(=O)O)n2)s1.O=C(Cl)C(=O)Cl>>CC(=O)Nc1nc(C)c(-c2csc(C(=O)Cl)n2)s1,,ClCCl,,CN(C)C=O,,test
US20110065708A1,C=C(OCC)c1ccc2ncc(C(C)c3c(F)cc4c(cnn4C)c3F)n2n1>>CC(=O)c1ccc2ncc(C(C)c3c(F)cc4c(cnn4C)c3F)n2n1,,CO,,Cl,O=C([O-])O.[Na+],test
US04544562,CC1CC(=O)NN=C1c1ccc(N)cc1.CCC(C#N)C(=O)Cl>>CCC(C#N)C(=O)Nc1ccc(C2=NNC(=O)CC2C)cc1,,CC(C)=O,,CCN(CC)CC,,test
US20120245345A1,CCOC(=O)c1cnc2ccc(OC)nc2c1Cl>>COc1ccc2ncc(C(=O)O)c(Cl)c2n1,,C1CCOC1,O,[Na+].[OH-],,test
US20110207783A1,COCCCc1ccc(Cl)c(CN(C(=O)C(Cc2cccnc2N)CN(C(=O)[O-])C(C)(C)C)C2CC2)c1>>COCCCc1ccc(Cl)c(CN(C(=O)C(CN)Cc2cccnc2N)C2CC2)c1,,ClCCl,,Cl,,test
US04959381,Nc1c(Cl)cc(C(=O)CBr)cc1C(F)(F)F.c1ccc(CCOCCCCCNCc2ccccc2)cc1>>Nc1c(Cl)cc(C(O)CN(CCCCCOCCc2ccccc2)Cc2ccccc2)cc1C(F)(F)F,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20120238599A1,CCOC(=O)c1c(Nc2ccc(I)cc2F)n(C)c(=O)c2c(C)coc12>>Cc1coc2c(C(=O)O)c(Nc3ccc(I)cc3F)n(C)c(=O)c12,,C1CCOC1,CO,O,O=C([O-])[O-].[K+].[K+],test
US20060004012A1,CCCCOc1ccc(C)cc1-c1ccc(CBr)cc1.CCOC(=O)CC(c1ccc(O)cc1)c1ccc(F)cc1>>CCCCOc1ccc(C)cc1-c1ccc(COc2ccc(C(CC(=O)OCC)c3ccc(F)cc3)cc2)cc1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20070219229A1,Cc1cn(C(=O)OC(C)(C)C)c2c(Cl)ncc(C(=O)NC(C)(C)C)c12.Nc1ccc(F)cc1F>>Cc1c[nH]c2c(Nc3ccc(F)cc3F)ncc(C(=O)NC(C)(C)C)c12,,CCOCC,,CO,,test
US20110086834A1,C#C[Mg]Br.CC(=O)c1nc(CO)cs1>>C#CC(C)(O)c1nc(CO)cs1,,C1CCOC1,,,,test
US20050203153A1,Nc1cccc(-c2nc3ccccc3o2)c1.O=C(O)c1ccc2c(c1)C(=O)OC2=O>>O=C(O)c1ccc2c(c1)C(=O)N(c1cccc(-c3nc4ccccc4o3)c1)C2=O,,CC(=O)O,,,,test
US20040092556A1,COC(=O)c1ccc(CN(Cc2ccccn2)C(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)N(Cc1ccc(C(=O)O)cc1)Cc1ccccn1,,C1CCOC1,,CO,[Na+].[OH-],test
US20060004013A1,CCOc1cc(C=O)ccc1F.Cc1c[nH]cn1>>CCOc1cc(C=O)ccc1-n1cnc(C)c1,,CN(C)C=O,,,,test
US20100174065A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1ccc(COc2cccc3c2OCCNC3)cc1>>CC(C)(C)OC(=O)N1CCOc2c(cccc2OCc2ccccc2)C1,,ClCCl,,,,test
US20130131036A1,CCOC(C)=O.N#CC1(c2ccc(C(F)(F)F)nc2)CCC1>>O=CC1(c2ccc(C(F)(F)F)nc2)CCC1,,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US04728663,NCCCn1ccnc1.SC1=Nc2ccc(Cl)c3cccc1c23>>Clc1ccc2c3c(cccc13)C(NCCCn1ccnc1)=N2,,CCO,,,,test
US06069143,COC(=O)CN1CCC(C(=O)Nc2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)cc2)CC1>>COC(=O)CN1CCC(C(=O)Nc2ccc(N3CCNCC3)cc2)CC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20160009683A1,CC(C)Oc1ccc(I)nc1.CCOC(=O)C(F)(F)Br>>CCOC(=O)C(F)(F)c1ccc(OC(C)C)cn1,[Cu],CS(C)=O,,[Cl-].[NH4+],,test
US20100210696A1,O=S(=O)(Nc1cc(CO)nn1-c1ccccc1)c1ccccc1>>O=Cc1cc(NS(=O)(=O)c2ccccc2)n(-c2ccccc2)n1,,CS(C)=O,,CCN(CC)CC,Cl,test
US20080021028A1,Brc1ncccn1.C[C@H]1CNCCN1>>Br.C[C@H]1CN(c2ncccn2)CCN1,,Cc1ccccc1C,,,,test
US20100081643A1,CI.S=c1[nH]c2cc(Cl)c(I)cc2[nH]1>>CSc1nc2cc(I)c(Cl)cc2[nH]1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150344453A1,Nc1ccccc1.OCc1ccccc1>>c1ccc(CNc2ccccc2)cc1,,Cc1ccccc1,,,,test
US20110021494A1,CCOC(=O)C(=O)Cl.CN(C)c1ccccc1.c1ccncc1>>CCOC(=O)C(=O)Nc1ccc(N(C)C)cc1,,ClCCl,,,,test
US20100331320A1,Cc1cc(Br)ccc1[C@H](C)N[S@](=O)C(C)(C)C>>Cc1cc(Br)ccc1[C@H](C)N,,CCOC(C)=O,,Cl,,test
US05798352,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](Cc1cccnc1)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](Cc1cccnc1)C(=O)O,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20100190825A1,CCN(C(C)C)C(C)C.CCO[C@@H]1CC[C@@H](N2CCC(Nc3ccc(C(F)(F)F)cc3Cl)CC2)CC1.ClCCl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCOC1CCC(N2CCC(n3c(=O)[nH]c4cc(C)c(Cl)cc43)CC2)CC1.Cl,,ClCCl,,O,,test
US05276024,Brc1csc2ccccc12.CCCC[Sn](Cl)(CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)c1csc2ccccc12,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US05011992,CC(=O)COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2>>CC(O)COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2,,CCO,,[BH4-].[Na+],,test
US20130059834A1,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](CC#N)C1.O=C(O)C(F)(F)F>>N#CC[C@H]1CC[C@@H](N)C1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20070117856A1,COC(=O)c1ccc(/C=C/c2n[nH]c3ccccc23)cc1>>O=C(O)c1ccc(/C=C/c2n[nH]c3ccccc23)cc1,,CO,,[Na+].[OH-],,test
US20110003836A1,NCC(O)Cn1c2ccc(Br)cc2c2cc(Br)ccc21.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=C1NCC(Cn2c3ccc(Br)cc3c3cc(Br)ccc32)O1,,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US20150045368A1,Brc1cnc2ccn(-c3ncccn3)c2c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(c2cnc3ccn(-c4ncccn4)c3c2)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US05854227,CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](N)[C@H]2SC1>>CC(=O)OCC1=C(C(=O)O)N2C(=O)C[C@H]2SC1,,c1ccncc1,,,,test
US20070032489A1,CCc1cc(C(=O)OC)c(C)nc1OC>>CCc1cc(C(=O)O)c(C)nc1OC,,CO,O,Cl,[Na+].[OH-],test
US20110092415A1,CC(C)(C)OC(=O)N1CCC[C@H]1c1nc2cc([C@@H](O)CC[C@H](O)c3cc4nc([C@@H]5CCCN5C(=O)OC(C)(C)C)n(COCC[Si](C)(C)C)c4cc3F)c(F)cc2n1COCC[Si](C)(C)C.CC(C)(C)c1ccc(N)cc1>>CC(C)(C)OC(=O)N1CCC[C@H]1c1nc2cc([C@H]3CC[C@H](c4cc5nc([C@@H]6CCCN6C(=O)OC(C)(C)C)n(COCC[Si](C)(C)C)c5cc4F)N3c3ccc(C(C)(C)C)cc3)c(F)cc2n1COCC[Si](C)(C)C,,CCOC(C)=O,ClCCl,CCN(CC)CC,CS(=O)(=O)Cl,test
US20150175604A1,CC(C)(C)OC(=O)NN(C(=O)OC(C)(C)C)c1ccc2c(cc(-c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)n2Cc2ccccc2)n1.CCI>>CCn1cnc(-c2cc3c(ccc4nnc(C)n43)n2Cc2ccccc2)c1,,CN(C)C=O,,[H-].[Na+],,test
US20150291563A1,NNc1cccc(Br)c1.O=C(C=Cc1ccc(F)cc1F)C(F)(F)C(F)(F)F>>Fc1ccc(C2CC(C(F)(F)C(F)(F)F)=NN2c2cccc(Br)c2)c(F)c1,,CC(=O)O,,Cl,,test
US20140094445A1,CC(=O)c1cc(Cl)ccc1O.NNC(=O)c1cccc(S(N)(=O)=O)c1>>C/C(=N\NC(=O)c1cccc(S(N)(=O)=O)c1)c1cc(Cl)ccc1O,,CC(=O)O,CO,,,test
US05591752,COC(=O)c1ccc(C#N)cc1COc1ccc(O)cc1>>N#Cc1ccc(C(=O)O)c(COc2ccc(O)cc2)c1,,CO,,[Na+].[OH-],,test
US20120094917A1,COC(=O)C1CN(S(C)(=O)=O)C2CCN(C(=O)C(NC(=O)C(C)N(C)C(=O)OC(C)(C)C)C3CCCCC3)C12>>CC(C(=O)NC(C(=O)N1CCC2C1C(C(=O)O)CN2S(C)(=O)=O)C1CCCCC1)N(C)C(=O)OC(C)(C)C,,CO,,[Na+].[OH-],,test
US20100098634A1,CN(C(=O)OC(C)(C)C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.FCCSc1nc2ccc(Br)cc2s1>>CN(C(=O)OC(C)(C)C)c1ccc(-c2ccc3nc(SCCF)sc3c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US20120288492A1,CSc1cnc(-c2ccc(NC(=O)Oc3ccccc3)cc2)nc1N1CCOCC1.OO>>CS(=O)c1cnc(-c2ccc(NC(=O)Oc3ccccc3)cc2)nc1N1CCOCC1,,ClCCl,,CC(=O)OC(C)=O,,test
US20100216788A1,COC(=O)c1cccc(O)c1.O=[N+]([O-])c1ccc(F)c(Cl)c1>>COC(=O)c1cccc(Oc2ccc([N+](=O)[O-])cc2Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05521192,CS(=O)(=O)OCCCCCc1cccc2ccccc12.[I-]>>ICCCCCc1cccc2ccccc12,,CC(C)=O,,O,,test
US20050054629A1,CC(C)(C)[SiH2]OC(C)(C)c1cc(=O)c(OCCCCCBr)co1.Clc1ccc2[nH]ccc2c1>>CC(C)(C)[SiH2]OC(C)(C)c1cc(=O)c(OCCCCCn2ccc3cc(Cl)ccc32)co1,,O,,CN(C)C=O,[H-].[Na+],test
US20150252030A1,COC(=O)COc1c(C)cc([N+](=O)[O-])cc1C.NN>>Cc1cc([N+](=O)[O-])cc(C)c1OCC(=O)NN,,CCO,,O,,test
US20130310427A1,Brc1ccc2ccccc2c1.O=C(Cl)CCl>>O=C(CCl)c1ccc2cc(Br)ccc2c1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US05604237,COc1ccc2c(c1OC)CCNC2.O=[N+]([O-])c1ccc(CCBr)cc1>>COc1ccc2c(c1OC)CCN(CCc1ccc([N+](=O)[O-])cc1)C2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130052151A1,BrP(Br)Br.C=CCCCCCCCCCO>>C=CCCCCCCCCCBr,,Cc1ccccc1,,,,test
US20090105484A1,CS(=O)(=O)Cl.O=C1O[C@@H](CO)CN1c1cccc(F)c1>>CS(=O)(=O)OC[C@H]1CN(c2cccc(F)c2)C(=O)O1,,Cc1ccccc1,,CCN(CC)CC,O,test
US20140303153A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.Cn1cc2c(c(-c3ccncc3)c1=O)C(=O)N(CCc1ccc3ccccc3n1)C2=O>>Cn1cc2c(c(-c3ccncc3)c1=O)C(=O)N(CCc1ccc3ccccc3n1)C2=S,,Cc1ccccc1,,,,test
US20110201605A1,C[Si](C)(C)C#N.Cc1cc(N2CCC(=O)CC2)ncn1.Nc1nc2c(-c3ccc(F)c(F)c3)cccn2n1>>Cc1cc(N2CCC(C#N)(Nc3nc4c(-c5ccc(F)c(F)c5)cccn4n3)CC2)ncn1,,CC(=O)O,,,,test
US20060264444A1,CC(=O)COc1ccc(Cl)cc1.NNc1ccc(F)cc1>>Cc1[nH]c2ccc(F)cc2c1Oc1ccc(Cl)cc1,,CCO,,,,test
US20140275019A1,NC(=O)Oc1ccccc1.O=C(/C=C/c1cnc2c(c1)CC1(CCNCC1)C(=O)N2)N1CC=C(Cc2nccs2)CC1>>NC(=O)N1CCC2(CC1)Cc1cc(/C=C/C(=O)N3CC=C(Cc4nccs4)CC3)cnc1NC2=O,,CS(C)=O,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US03945998,CC(N)(CO)COCc1ccccc1.O=C(O)c1ccc([N+](=O)[O-])cc1>>CC1(COCc2ccccc2)COC(c2ccc([N+](=O)[O-])cc2)=N1,,Cc1ccccc1C,,,,test
US05006561,CNC1Cc2ccc([N+](=O)[O-])cc2C1.O=[N+]([O-])c1ccc(CCBr)cc1>>CN(CCc1ccc([N+](=O)[O-])cc1)C1Cc2ccc([N+](=O)[O-])cc2C1,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US06710052B2,CC(C)CNCC(O)COc1ccc(N)cc1.COc1ccc(Oc2nc(Nc3ccc(OCC(O)CN(C)C)cc3)ncc2Br)cc1>>COc1ccc(Oc2nc(Nc3ccc(OCC(O)CNCC(C)C)cc3)ncc2Br)cc1,,CN1CCCC1=O,,Cl,,test
US20150018328A1,COC(=O)c1cnccn1.O=C(OO)c1cccc(Cl)c1>>COC(=O)c1cncc[n+]1[O-],,ClCCCl,,,,test
US06217793B1,CCCCCCCCCCCCC(=O)Oc1ccc(C(=O)Oc2ccc(OCc3ccccc3)cc2)cc1>>CCCCCCCCCCCCC(=O)Oc1ccc(C(=O)Oc2ccc(O)cc2)cc1,[Pd],CCOC(C)=O,,,,test
US20060100191A1,CN(C)C(=O)N1CC(c2cc(Cl)ccc2F)=CC1(CCCN)c1ccccc1.C[Si](C)(C)N=C=O>>CN(C)C(=O)N1CC(c2cc(Cl)ccc2F)=CC1(CCCNC(N)=O)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20030181468A1,Cc1sc2ncnc(N)c2c1-c1ccc(N)cc1.O=C=Nc1ccccc1>>Cc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2ccccc2)cc1,,ClCCl,,,,test
US20140256707A1,COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc3c(-c4ccc(C(F)(F)F)cc4-c4ccnn4C)cn(C(=O)OC(C)(C)C)c3n2)c(OC)c1>>COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc3c(-c4ccc(C(F)(F)F)cc4-c4ccnn4C)c[nH]c3n2)c(OC)c1,,CCOC(C)=O,,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20060205767A1,C#Cc1ccc(OC)cc1.O=Cc1cccnc1Br>>COc1ccc(C#Cc2ncccc2C=O)cc1,[Cu]I,CCN(CC)CC,,,,test
US20070003539A1,COC(C)=O.Cc1ccc([S@](=O)/N=C/c2cc([N+](=O)[O-])ccc2SC(C)C)cc1>>COC(=O)C[C@@H](N[S@@](=O)c1ccc(C)cc1)c1cc([N+](=O)[O-])ccc1SC(C)C,,C1CCOC1,CCOCC,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20070276000A1,CCCCc1cc2ccccc2c(Oc2ccc(C=O)cc2)c1-c1ccccc1.O=C(O)CC(=O)O>>CCCCc1cc2ccccc2c(Oc2ccc(/C=C/C(=O)O)cc2)c1-c1ccccc1,C1CCNCC1,c1ccncc1,,CO,,test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCc1ccccc1.Cl.Nc1ccc2[nH]ccc2c1>>COc1cc2c(Nc3ccc4[nH]ccc4c3)ncnc2cc1OCc1ccccc1.Cl,,CC(C)O,,,,test
US04810800,BrCc1ccsc1.c1c[nH]cn1>>c1cn(Cc2ccsc2)cn1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US07312225B2,Clc1ncc(Br)c(Cl)n1.NCCCCO>>OCCCCNc1nc(Cl)ncc1Br,,CC#N,,CCN(CC)CC,,test
US20040053908A1,Clc1ncnc2sccc12.O=[N+]([O-])c1ccc(O)cc1>>O=[N+]([O-])c1ccc(Oc2ncnc3sccc23)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20020115620A1,COc1cc(C=O)ccc1F.c1cn[nH]c1>>COc1cc(C=O)ccc1-n1cccn1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20090099231A1,C=O.CC(Cc1cccc([N+](=O)[O-])c1)NS(C)(=O)=O>>CC1Cc2cc([N+](=O)[O-])ccc2CN1S(C)(=O)=O,,CC(=O)O,,O=S(=O)(O)O,,test
US20160039783A1,CCOC(=O)C(OC(C)(C)C)c1c(C)sc(C2=CC(=O)N(C(=O)OC(C)(C)C)C2)c1C1=CCC(C)(C)CC1>>CCOC(=O)C(OC(C)(C)C)c1c(C)sc(C2=CC(=O)NC2)c1C1=CCC(C)(C)CC1,,CCOC(C)=O,,Cl,,test
US20160083349A1,C[C@H](N[S@@](=O)C(C)(C)C)c1cc2cc(Cl)ccc2[nH]c1=O.Cl>>C[C@H](N)c1cc2cc(Cl)ccc2[nH]c1=O.Cl,,CO,,CCOCC,,test
US20160264552A1,C=O.Nc1cccc(CN2CCC(Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)CC2)c1>>CNc1cccc(CN2CCC(Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)CC2)c1,,CO,,[BH3-]C#N.[Na+],,test
US20150291577A1,CC(C)(C)OC(=O)NC1CC1c1ccc(Br)s1.Cl>>Cl.N[C@@H]1C[C@H]1c1ccc(Br)s1,,CCOC(C)=O,,,,test
US03981871,COC(OC)N(C)C.O=[N+]([O-])C=C1NCCCS1>>CN(C)C=C(C1=NCCCS1)[N+](=O)[O-],,ClC(Cl)Cl,,,,test
US20150291572A1,CN(C)C=O.O=S(=O)(c1cccc(C(F)(F)F)c1)C1CCOC(c2ccc(Br)nc2)C1>>CC1(S(=O)(=O)c2cccc(C(F)(F)F)c2)CCOC(c2ccc(Br)nc2)C1,,C1CCOC1,CN(C)C=O,CC(C)(C)[O-].[K+],,test
US20040247639A1,CCOC(=O)CCC(C)=O.COc1ccc(NN)cc1>>CCOC(=O)Cc1c(C)[nH]c2ccc(OC)cc12,,Cl,,,,test
US20080004304A1,O=C1Nc2ncnc(Cl)c2C12Cc1ccc([N+](=O)[O-])cc1C2>>Nc1ccc2c(c1)CC1(C2)C(=O)Nc2ncnc(Cl)c21,[Pd],CCOC(C)=O,,CCN(CC)CC,[H][H],test
US03948952,CCC(=O)OC(=O)CC.CNC(=O)Oc1cccc2c1OC(C)(C)O2>>CCC(=O)N(C)C(=O)Oc1cccc2c1OC(C)(C)O2,O=S(=O)(O)O,,,CC(=O)[O-].[Na+],,test
US20020193367A1,CC(C)(C)OC(=O)CC(=O)c1cccc(-c2nc(COC3CCCCO3)co2)c1.CCCN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1C>>CCCN(C)c1cc2c(cc1C)NC(=O)CC(c1cccc(-c3nc(CO)co3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140018313A1,COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1)C(C)C.COC[C@H]1C[C@@H](c2nc3ccc4cc(Br)ccc4c3[nH]2)N(C(=O)OC(C)(C)C)C1>>COC[C@H]1C[C@@H](c2nc3ccc4cc(-c5ccc(-c6cnc([C@@H]7CCCN7C(=O)[C@@H](NC(=O)OC)C(C)C)[nH]6)cc5)ccc4c3[nH]2)N(C(=O)OC(C)(C)C)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20090181942A1,CCOC(=O)C[C@H]1O[C@H](c2cccnc2C(F)(F)F)c2cc(Cl)ccc2-n2c1nnc2C(F)(F)F>>O=C(O)C[C@H]1O[C@H](c2cccnc2C(F)(F)F)c2cc(Cl)ccc2-n2c1nnc2C(F)(F)F,,C1COCCO1,,Cl,O,test
US04456612,O=C(c1ccccc1F)c1cc2c(c(Cl)c1Cl)OC(CO)C2.O=[Cr](=O)=O>>O=C(c1ccccc1F)c1cc2c(c(Cl)c1Cl)OC(C(=O)O)C2,,CC(C)=O,,O=S(=O)(O)O,,test
US20160024021A1,COC(=O)c1cc(CCc2cnc(Nc3ccc(CN4CCOCC4)cn3)nc2)c(F)c(OC)c1>>COc1cc(C(=O)O)cc(CCc2cnc(Nc3ccc(CN4CCOCC4)cn3)nc2)c1F,,C1CCOC1,,[Li+].[OH-],,test
US20080146606A1,CON(C)C(=O)C1(C)CC1.Cc1cccnc1NC(=O)OC(C)(C)C>>CC1(c2cc3cccnc3[nH]2)CC1,,C1CCOC1,,Cl,[Li]CCCC,test
US06492416B1,BrBr.CSc1ccc(C2=CC(=O)C(C)(C)O2)cc1>>CSc1ccc(C2=C(Br)C(=O)C(C)(C)O2)cc1,,ClC(Cl)(Cl)Cl,,CC(=O)O,,test
US20040147739A1,CC(C)COc1nc2c(Br)cccc2c(=O)o1.CCOC(=O)CC1=Nc2ccccc2S(=O)(=O)N1>>O=c1[nH]c2c(Br)cccc2c(O)c1C1=Nc2ccccc2S(=O)(=O)N1,,C1CCOC1,,CC(=O)O,[H-].[Na+],test
US20060106084A1,CCCn1nc(C(O)c2cccc(OCc3ccccc3)c2)c2ccccc21>>CCCn1nc(C(O)c2cccc(O)c2)c2ccccc21,[Pd],CCO,,O=C[O-].[NH4+],,test
US05525632,COc1ccc(/C=C\c2cc(OC)c(OC)c(OC)c2)cc1[N+](=O)[O-]>>COc1ccc(/C=C\c2cc(OC)c(OC)c(OC)c2)cc1N,[Zn],CC(=O)O,,,,test
US05428021,CC(=O)Nc1ccc([N+](=O)[O-])c(C)c1C(=O)O>>Cc1c([N+](=O)[O-])ccc(N)c1C(=O)O,,[Na+],[OH-],Cl,,test
US20140142082A1,Cc1c(S(N)(=O)=O)cc(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)n1CC1CCCCC1.ClCCOCCCl>>Cc1c(S(=O)(=O)N2CCOCC2)cc(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)n1CC1CCCCC1,,CN(C)C=O,,[H-].[Na+],,test
US20060069095A1,FC(F)(F)Oc1ccc(/C=C/c2nc(COc3ccc(CCCCc4c[nH]nn4)cc3)co2)cc1.OCCCBr>>OCCCn1ncc(CCCCc2ccc(OCc3coc(/C=C/c4ccc(OC(F)(F)F)cc4)n3)cc2)n1,,CN(C)C=O,,[H-].[Na+],,test
US20110190489A1,CC(C)(C)OC(=O)N1CCC(O)C1.Cc1ccc(S(=O)(=O)n2ccc3c2ncc2c(-c4ccc(O)cc4)ncn23)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c2ncc2c(-c4ccc(OC5CCN(C(=O)OC(C)(C)C)C5)cc4)ncn23)cc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110021522A1,CCOc1ncccc1-c1cccc(N)c1.O=C(O)c1cc2cccc(O)c2oc1=O>>CCOc1ncccc1-c1cccc(NC(=O)c2cc3cccc(O)c3oc2=O)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070259886A1,CC(C)c1cc(C(=O)O)c(OCc2ccccc2)cc1OCc1ccccc1.O=C(Cl)C(=O)Cl>>CC(C)c1cc(C(=O)Cl)c(OCc2ccccc2)cc1OCc1ccccc1,,ClCCl,,CN(C)C=O,,test
US20110178107A1,C=C[C@@H]1CC1(NC(=O)[C@@H]1C[C@@H](Oc2nc(-c3ccc(OC(C)C)cc3)nc3c2oc2ccccc23)CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)C(=O)NS(=O)(=O)C1CC1.Cl>>C=C[C@@H]1CC1(NC(=O)[C@@H]1C[C@@H](Oc2nc(-c3ccc(OC(C)C)cc3)nc3c2oc2ccccc23)CN1C(=O)[C@@H](N)C(C)(C)C)C(=O)NS(=O)(=O)C1CC1.Cl,,ClCCl,,C1COCCO1,,test
US05102891,Fc1cnccc1Nn1ccc2cc(OCc3ccccc3)ccc21>>Oc1ccc2c(ccn2Nc2ccncc2F)c1,[Pd],CCO,,[H][H],,test
US04686227,Cc1nc2c3cccc(Cl)c3ccn2c1CSCCN.O=S1(=O)N=C(Cl)c2ccccc21>>Cc1nc2c3cccc(Cl)c3ccn2c1CSCCNC1=NS(=O)(=O)c2ccccc21,,CCO,,CCN(CC)CC,,test
US20090203667A1,COC(=O)c1ccnc(Cl)c1N>>Nc1c(CO)ccnc1Cl,,C1CCOC1,,[BH4-].[Li+],,test
US20040157739A1,COCC(=O)N[C@H]1c2ccccc2C[C@@H]1C.Cl>>C[C@H]1Cc2ccccc2[C@@H]1N.Cl,,CCO,O,,,test
US20050131014A1,Nc1ccc(-c2c(C(=O)c3ccccc3)cnc3c(C(F)(F)F)cccc23)cc1.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)Nc1ccc(-c2c(C(=O)c3ccccc3)cnc3c(C(F)(F)F)cccc23)cc1,,CCN(CC)CC,,,,test
US04093812,O=C(O)c1cn(-c2ccccc2)nc1-c1ccc([N+](=O)[O-])o1>>O=[N+]([O-])c1ccc(-c2nn(-c3ccccc3)cc2CO)o1,,C1COCCO1,,,,test
US20020143020A1,CC(C)(C)OC(=O)N1CCN(C(=O)Cl)CC1.OCc1ccc(OCc2ccccc2)cc1.S=C=S>>CC(C)(C)OC(=O)N1CCN(C(=O)SCc2ccc(OCc3ccccc3)cc2)CC1,,CC(C)=O,O,[K+].[OH-],,test
US20080009515A1,N#Cc1cccc(O)c1.[N-]=[N+]=[N-].[NH4+]>>Oc1cccc(-c2nn[nH]n2)c1,,CN(C)C=O,,[Cl-].[Na+],,test
US04743291,COc1cc(-n2nc(C)n(C(F)F)c2=O)c(F)cc1Cl>>Cc1nn(-c2cc(O)c(Cl)cc2F)c(=O)n1C(F)F,,ClCCl,,BrB(Br)Br,O,test
US20100144731A1,C1COCCN1.Clc1nc(Cl)c2c(n1)CCC2>>Clc1nc2c(c(N3CCOCC3)n1)CCC2,,CCO,,,,test
US20100227894A1,COc1ccc(B(O)O)cc1OC.NC(=O)c1ccc(Cl)c(N)c1.O=CC(=O)O>>COc1ccc(C(Nc2cc(C(N)=O)ccc2Cl)C(=O)O)cc1OC,,CN(C)C=O,ClCCl,O,,test
US06911442B1,CCCCCCCN1CCN(C(=O)OC(C)(C)C)C[C@H]1CO.O=C(O)C(F)(F)F>>CCCCCCCN1CCNC[C@H]1CO.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20160207949A1,BrCc1ccccc1.COc1cc(C(=O)O)ccc1O>>COc1cc(C(=O)O)ccc1OCc1ccccc1,,CCO,,[Na+].[OH-],,test
US20100285145A1,C=O.CO.Cl.NCc1ccccc1.O=C1CCOCC1>>Cl.O=C1C2COCC1CN(Cc1ccccc1)C2,,C1COCCO1,CO,CC(=O)O,,test
US20070185324A1,Cc1ccc2c(c1)C(O)N(C(C)(C)C)C2=O.NN>>Cc1ccc2c(=O)[nH]ncc2c1,,CC(=O)O,O,,,test
US20100298324A1,COc1ccc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)nc1OC.NCc1ccc(Cl)cc1>>COc1ccc(-n2c(=S)[nH]c3cc(C(=O)NCc4ccc(Cl)cc4)ccc3c2=O)nc1OC,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130196974A1,C=C[Sn](CCCC)(CCCC)CCCC.O=S1(=O)CCN(c2cc(Cl)c3cc(OC(F)(F)F)ccc3n2)Cc2ccccc21>>C=Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(Cl)c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US20140107194A1,O=C(O)CNC(=O)OCC1c2ccccc2-c2ccccc21.O=C(O)c1ccc(C[C@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@@H]2O)cc1>>NCC(=O)O[C@H]1c2ccccc2C[C@]1(Cc1ccc(C(=O)O)cc1)C1=Cc2ccccc2C1,CN(C)c1ccncc1,CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20130196970A1,CC(C)(C)OC(=O)N1CC(N[C@H]2CCNC2)C1.O=C(O)c1ccccc1>>CC(C)(C)OC(=O)N1CC(N[C@H]2CCN(C(=O)c3ccccc3)C2)C1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05514878,BrCCCCCCCCBr.O=Cc1ccc(O)cc1>>CCCCC(C=O)CCCOc1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050043351A1,O=C(Nc1cccc2[nH]ncc12)NC1CCc2c1cccc2N1CCCCC1>>O=C(Nc1cccc2[nH]ncc12)N[C@@H]1CCc2c1cccc2N1CCCCC1,,CO,,Cl,,test
US20040209920A1,CCOC(=O)C(=CCO[C@@H]1CCC[C@H](OCc2nc(-c3ccc(F)cc3)oc2C)C1)CC>>CCC(=CCO[C@@H]1CCC[C@H](OCc2nc(-c3ccc(F)cc3)oc2C)C1)C(=O)O,,CCOC(C)=O,CO,Cl,[Na+].[OH-],test
US03993656,CCOC(=O)c1c(N)nc(C)c(NC(C)=O)c1C.NN>>CC(=O)Nc1c(C)nc(N)c(C(=O)NN)c1C,,CO,O,,,test
US20090111859A1,C=C(C)C(CC(=O)OCC)c1ccc(OC2CCCCO2)cc1>>C=C(C)C(CC(=O)OCC)c1ccc(O)cc1,,CCO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US06809097B1,BrCc1ccccc1.COc1ccc(NC=C2C(=O)OC(C)(C)OC2=O)cc1O>>COc1ccc(NC=C2C(=O)OC(C)(C)OC2=O)cc1OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05112988,COc1ccccc1CC(=O)O.O=C1CCC(c2ccccc2)(c2ccccc2)[C@@H]2CNC[C@H]12>>COc1ccccc1CC(=O)N1C[C@@H]2C(=O)CCC(c3ccccc3)(c3ccccc3)[C@@H]2C1,,ClCCl,,CCN(CC)CC,Cl,test
US20120277423A1,C=CC(=O)Cl.Cc1cc(C)cc(C(C)(C)C)c1>>C=CC(=O)c1c(C)cc(C(C)(C)C)cc1C,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100152168A1,CC(C)(C)OC(=O)N1CC[C@H](N)C1.CN1CCC(=O)CC1>>CN1CCC(N[C@H]2CCN(C(=O)OC(C)(C)C)C2)CC1,,C1CCOC1,,,,test
US20120277224A1,CC(=O)CC#N.O=Cc1ccccc1>>CC(=O)C(C#N)=Cc1ccccc1,,Cc1ccccc1,,C1CCNCC1,CC(=O)O,test
US20090118283A1,CC(C)(C)OC(=O)CC(NC(=O)OC(C)(C)C)c1ccc(C(=O)Nc2ccncc2)cc1>>CC(C)(C)OC(=O)NC(CC(=O)O)c1ccc(C(=O)Nc2ccncc2)cc1,,C1CCOC1,,[Li+].[OH-],,test
US20140171420A1,CC(C)c1c(N2CCC(n3nc(C#N)c4cccnc43)C2=O)cnn1-c1ccc(F)cc1.NCCN>>CC(C)c1c(N2CCC(n3nc(C4=NCCN4)c4cccnc43)C2=O)cnn1-c1ccc(F)cc1,,CC(=O)O,CCO,,,test
US05294718,COC(OC)c1cc(N2CCC(O)CC2)ccc1[N+](=O)[O-]>>O=Cc1cc(N2CCC(O)CC2)ccc1[N+](=O)[O-],,CC(C)=O,,Cl,O,test
US20060258691A1,CC(C)CN.Cc1ccc(C(=O)Nc2ccc3c(C(=O)O)cn(C(C)(C)C)c3n2)cc1>>Cc1ccc(C(=O)Nc2ccc3c(C(=O)NCC(C)C)cn(C(C)(C)C)c3n2)cc1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090227591A1,CC(=O)Cl.CCOC(=O)c1cc(C2=C(c3cc(Cl)ccc3OCc3ccccc3)CCC2)ccc1N>>CCOC(=O)c1cc(C2=C(c3cc(Cl)ccc3OCc3ccccc3)CCC2)ccc1NC(C)=O,,ClCCl,,CCN(CC)CC,,test
US20080312234A1,CCOC(=O)COc1ccc(Cl)nc1>>O=C(O)COc1ccc(Cl)nc1,,C1CCOC1,O,[Li+].[OH-],,test
US20090062223A1,CC(C)(C)[SiH2]OC(c1ccccc1)(c1ccccc1)C1OC(n2cc3c(N)cc4c(=O)[nH]ncc(n2)c34)C(C)(O)C1O.CCCCCC(=O)Cl>>CCCCCC(=O)OC1C(C(O[SiH2]C(C)(C)C)(c2ccccc2)c2ccccc2)OC(n2cc3c(N)cc4c(=O)[nH]ncc(n2)c34)C1(C)O,CN(C)c1ccncc1,c1ccncc1,,,,test
US20090215725A1,CC[Si](C#CCOCC1CCC(N(C)C)(n2ccnn2)CC1)(CC)CC.Cl[Mg]c1ccccc1>>CC[Si](C#CCOCC1CCC(c2ccccc2)(N(C)C)CC1)(CC)CC,,C1CCOC1,,O,[Cl-].[NH4+],test
US20160199371A1,COc1cc(OC)c(F)c(COc2cnc(Nc3cnn(C[C@@H]4COC(C)(C)O4)c3)nc2)c1F>>COc1cc(OC)c(F)c(COc2cnc(Nc3cnn(C[C@@H](O)CO)c3)nc2)c1F,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US05502053,COC(=O)/C=C/CC1CCCCC1>>OC/C=C/CC1CCCCC1,,CCOCC,,CC(C)C[AlH]CC(C)C,,test
US05068272,CCCSCCCN(CC)CC(O)COc1ccc(C#N)cc1.O=C(OO)c1cccc(Cl)c1>>CCCS(=O)CCCN(CC)CC(O)COc1ccc(C#N)cc1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090186870A1,CN1CCC(S(=O)(=O)c2ccc3nc(N)sc3c2)CC1.O=C(Cl)Oc1ccc(F)cc1>>CN1CCC(S(=O)(=O)c2ccc3nc(NC(=O)Oc4ccc(F)cc4)sc3c2)CC1,,CN(C)C=O,,c1ccncc1,,test
US20070093484A1,CCCCO.NN1CCCCC1.O=C1OC(=O)c2nc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)nc21>>CCCCOC(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1C(=O)NN1CCCCC1,CN(C)c1ccncc1,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160264598A1,CC(C)(C)OC(=O)c1c(O)c(I)cc(F)c1F.CI>>COc1c(I)cc(F)c(F)c1C(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130217680A1,CCOC(=O)Cc1ccc(C#N)c(OC)c1>>COc1cc(CC(=O)O)ccc1C#N,,C1CCOC1,,CO,[Li+].[OH-],test
US20070010573A1,CCN.O=S1(=O)CCCO1>>CCNCCCS(=O)(=O)O,,C1CCOC1,,,,test
US20100234351A1,CC(C)(C)OC(=O)NC1CCN(C(=O)c2ccc([N+](=O)[O-])cc2Cl)CC1>>CC(C)(C)OC(=O)NC1CCN(C(=O)c2ccc(N)cc2Cl)CC1,,CCO,O,[Ca+2].[Cl-].[Cl-],,test
US20080161366A1,CN.O=S1(=O)N(CCCCBr)c2ccccc2N1c1ccccc1>>CNCCCCN1c2ccccc2N(c2ccccc2)S1(=O)=O,,CO,,,,test
US05569768,CCCCCC(c1nccn1CC(=O)OCC)n1cnc2cc(-c3ccccc3C#N)ccc21>>CCCCCC(c1nccn1CC(=O)O)n1cnc2cc(-c3ccccc3C#N)ccc21,,CCO,,[Na+].[OH-],,test
US20080039506A1,CC(=O)OCCCS(=O)(=O)NC(=O)c1ccc(B(O)O)cc1C1CCCC1>>O=C(NS(=O)(=O)CCCO)c1ccc(B(O)O)cc1C1CCCC1,,CO,Cl,,,test
US05719297,C[C@H](C[C@@H]1C=CC(=O)C1)[C@H]1CCC2C(O[Si](C)(C)C)CCC[C@@]21C.[Li]C>>C[C@H](C[C@@H]1C=C[C@](C)(O)C1)[C@H]1CCC2C(O[Si](C)(C)C)CCC[C@@]21C,,CCOCC,,C1CCOC1,,test
US05130339,COc1ccc2c(c1)C[C@@H](C(N)=O)CC2.Cl>>COc1ccc2c(c1)C[C@@H](CN)CC2.Cl,,CC(C)O,,,,test
US20090163566A1,CC(=N)NO.CCOC(=O)c1cn(-c2cccc(Br)c2)cn1>>Cc1noc(-c2cn(-c3cccc(Br)c3)cn2)n1,,C1CCOC1,,[H-].[Na+],,test
US20150197509A1,CC(C)(C)OC(=O)NCc1cccc(-c2ccc(C(F)(F)F)nn2)c1>>NCc1cccc(-c2ccc(C(F)(F)F)nn2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120101083A1,CCOc1ncc(-c2nc(-c3ccc4c(c3)CCN(C3COC(C)(C)OC3)CC4)no2)cc1C#N>>CCOc1ncc(-c2nc(-c3ccc4c(c3)CCN(C(CO)CO)CC4)no2)cc1C#N,,C1CCOC1,,Cl,,test
US20020161041A1,C[Mg]Cl.O=C1CCCC(c2ccc(O)cc2O)C1>>CC1(O)CCCC(c2ccc(O)cc2O)C1,,C1CCOC1,,Cl,,test
US20090264434A1,CC(=O)c1ccccc1Oc1cnn(C2CCCCO2)c(=O)c1Cl>>CC(=O)c1ccccc1Oc1cn[nH]c(=O)c1Cl,,CO,,Cl,O,test
US06326386B1,CC(C)(C)OC(=O)N(CCOc1cc(Cl)cc(C(=O)O)c1)c1ccncc1.CCOC(=O)C1CCCCN1>>CCOC(=O)C1CCCCN1C(=O)c1cc(Cl)cc(OCCN(C(=O)OC(C)(C)C)c2ccncc2)c1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20090298744A1,CCCn1c(=O)c2[nH]c(-c3ccc(OCc4ccccc4)cc3)nc2n(CCC)c1=O.C[Si](C)(C)CCOCCl>>CCCn1c(=O)c2c(nc(-c3ccc(OCc4ccccc4)cc3)n2COCC[Si](C)(C)C)n(CCC)c1=O,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20050277674A1,CN(C)C1(c2ccccc2)CCC(CNC(=O)Oc2ccc([N+](=O)[O-])cc2)CC1.Fc1ccc2[nH]cc(C3CCCNC3)c2c1>>CN(C)C1(c2ccccc2)CCC(CNC(=O)N2CCCC(c3c[nH]c4ccc(F)cc34)C2)CC1,,C1COCCO1,,,,test
US20150264932A1,CC(C)(C)OC(=O)N(CCO)CCO.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)N1CCOC(=O)OCC1,,ClCCl,,CCN(CC)CC,,test
US20040121964A1,COC(=O)[C@@H]1CC[C@H](C#C[Si](C)(C)C)N1C(=O)[C@@H](NC(=O)OC(C)(C)C)C1CCCC1>>C#C[C@H]1CC[C@@H](C(=O)O)N1C(=O)[C@@H](NC(=O)OC(C)(C)C)C1CCCC1,,CO,O,[Li]O,,test
US20060178421A1,CCC[C@H](N[C@@H](C)C(=O)O)C(=O)OCC.O=S(Cl)n1ccnc1>>CCC[C@@H](C(=O)OCC)N1[C@@H](C)C(=O)OS1=O,,ClCCl,,,,test
US20090274632A1,Cc1noc(C)c1Cn1cnc(N)c1.O=C(Cl)c1ccc2c(c1)OCO2>>Cc1noc(C)c1Cn1cnc(NC(=O)c2ccc3c(c2)OCO3)c1,,ClCCl,,CCN(CC)CC,,test
US20140142082A1,C#CCBr.Oc1ccccc1C(F)(F)F>>C#CCOc1ccccc1C(F)(F)F,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060025414A1,CC(C)(C)OC(=O)N1CCCC1c1cc(-c2cccc(Cl)c2)on1>>Clc1cccc(-c2cc(C3CCCN3)no2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04150224,CCCC(=O)NCCl.Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(NC(=O)Cn3cccc3)C2SC1>>CCCC(=O)NCOC(=O)C1=C(CSc2nnnn2C)CSC2C(NC(=O)Cn3cccc3)C(=O)N12,,CN(C)C=O,,[Na],,test
US20030236269A1,CC(C)(C)OC(=O)N1CCC(O)(c2ccc(Oc3ccccc3)cc2)CC1>>C1=C(c2ccc(Oc3ccccc3)cc2)CCNC1,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US06204264B1,CCCCCCCCCCCCCCCCCCN.O=[N+]([O-])c1ccccc1Cl>>CCCCCCCCCCCCCCCCCCNc1ccccc1[N+](=O)[O-],,CCCCCC,,,,test
US20110105542A1,CCc1cccc(CC)c1NC(=O)c1nn(C)c2c1CCc1cnc(NC3CCNCC3)nc1-2.CS(=O)(=O)Cl>>CCc1cccc(CC)c1NC(=O)c1nn(C)c2c1CCc1cnc(NC3CCN(S(C)(=O)=O)CC3)nc1-2,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US06100272,COC(=O)c1ccc(-c2ccc(N3CCCC3=O)cc2C)cc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COC(=O)c1ccc(-c2ccc(N3CCCC3=S)cc2C)cc1,,Cc1ccccc1,,,,test
US20080269268A1,CI.C[Si](C)(C)CCOCn1ccc2c(Nc3ccc([N+](=O)[O-])cc3F)ccnc21>>CN(c1ccc([N+](=O)[O-])cc1F)c1ccnc2c1ccn2COCC[Si](C)(C)C,,CC(=O)N(C)C,,O,[H-].[Na+],test
US05021435,CC1SC(c2cccnc2)NC1=O.CCOC(=O)CBr>>CCOC(=O)CN1C(=O)C(C)SC1c1cccnc1,,CN(C)C=O,,[H-].[Na+],,test
US20090143361A1,COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)cc(Cl)c4)n3c2n1.OB(O)c1cccc(Cl)c1Cl>>COc1ccc2nc(C)c3c(C)nc(-c4cccc(Cl)c4Cl)n3c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US05132319,C[Si](C)(C)Cl.O=C(O)Cn1ccc2ccccc21>>CC(=O)Cn1ccc2ccccc21,,CCOCC,,,,test
US20050245518A1,CN(C)CCO.Nc1cc(F)c(F)cc1[N+](=O)[O-]>>CN(C)CCOc1cc(N)c([N+](=O)[O-])cc1F,,c1ccncc1,,[H-].[Na+],,test
US20070032485A1,CCOC(=O)N1c2ccc(OC)nc2[C@@H](Nc2ncc(N3CCOCC3)c(Cc3cc(C(=O)OC)cc(C(F)(F)F)c3)n2)C[C@H]1CC>>CCOC(=O)N1c2ccc(OC)nc2[C@@H](Nc2ncc(N3CCOCC3)c(Cc3cc(C(=O)O)cc(C(F)(F)F)c3)n2)C[C@H]1CC,,CN(C)C=O,CO,[Na+].[OH-],,test
US05856556,CC(=NC(=O)OCc1ccc([N+](=O)[O-])cc1)N1CC[C@H](SC(=O)C[C@@H]2[C@@H]([C@@H](C)OC(=O)OCc3ccc([N+](=O)[O-])cc3)C(=O)N2C(C(=O)OCc2ccc([N+](=O)[O-])cc2)=C(C)C)C1>>CC(=NC(=O)OCc1ccc([N+](=O)[O-])cc1)N1CC[C@H](SC(=O)C[C@@H]2[C@@H]([C@@H](C)OC(=O)OCc3ccc([N+](=O)[O-])cc3)C(=O)N2CCOCc2ccc([N+](=O)[O-])cc2)C1,,ClCCl,,,,test
US20130237502A1,C[Mg]Br.O=Cc1ccc(Br)cn1>>CC(O)c1ccc(Br)cn1,,C1CCOC1,,[Cl-].[NH4+],,test
US05559113,ClCc1c[nH]cn1.NC(N)=S.O=[N+]([O-])c1ccc(Cl)nc1>>O=[N+]([O-])c1ccc(SCc2c[nH]cn2)nc1,,CCO,O,[Na+].[OH-],,test
US20040077877A1,Fc1ccc(-c2nn(C3CCCCO3)c3ccc(C#Cc4ccccc4)cc23)cc1>>Fc1ccc(-c2n[nH]c3ccc(C#Cc4ccccc4)cc23)cc1,,C1CCOC1,,Cl,,test
US20140275058A1,CCN(CC)S(F)(F)F.OCC1=NOC(CCl)C1>>FCC1=NOC(CCl)C1,,ClCCl,,,,test
US20150065522A1,CN(C)/C=C(\C#N)n1ccnc1.NN>>Nc1[nH]ncc1-n1ccnc1,,CCO,,Cl,O,test
US20080064682A1,CCOC(=O)c1cc(-c2ccc(OCc3ccccc3)cn2)n(-c2cccnc2)n1>>O=C(O)c1cc(-c2ccc(OCc3ccccc3)cn2)n(-c2cccnc2)n1,,C1CCOC1,CO,[Na+].[OH-],,test
US04396622,COc1ccc(S(=O)(=O)Cl)cc1.NCCCN1CCCC1.O=S(=O)(Cl)Cl>>COc1ccc(S(=O)(=O)NCCC[NH+]2CCCC2)cc1.[Cl-],,[Na+],[OH-],,,test
US06054568,COc1ccc(C(Cl)(c2ccccc2)c2ccc(OC)cc2)cc1.O=c1[nH]cc(CO)c(=O)[nH]1>>COc1ccc(C(OCc2c[nH]c(=O)[nH]c2=O)(c2ccccc2)c2ccc(OC)cc2)cc1,,c1ccncc1,,CCN(CC)CC,O,test
US06057295,C(=NC1CCCCC1)=NC1CCCCC1.Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)OCc2ccccc2)C(=O)O)c(C)c2c1OC(C)(C)CC2>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)OCc2ccccc2)C(N)=O)c(C)c2c1OC(C)(C)CC2,,CN(C)C=O,,,,test
US20080227807A1,CCOC(=O)/C=C/c1cc2cc(OC)cnc2n1Cc1ccc(Cl)cc1>>CCOC(=O)CCc1cc2cc(OC)cnc2n1Cc1ccc(Cl)cc1,[Pd],CCO,CCOC(C)=O,,,test
US20060167065A1,CC(C)(C)c1ccc(N)cc1.COC(=O)c1cccc(NC(=O)Oc2ccc([N+](=O)[O-])cc2)c1>>COC(=O)c1cccc(NC(=O)Nc2ccc(C(C)(C)C)cc2)c1,,c1ccncc1,,,,test
US05346911,CCOC(=O)C=[N+]=[N-].c1ccccc1>>CCOC(=O)C1=CC=CC=CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20060142585A1,Cl.N#C[C@@H]1C[C@H](F)CN1C(=O)CN[C@@H]1CC[C@H](Cn2cncn2)C1>>Cl.N#C[C@@H]1C[C@H](F)CN1C(=O)CN[C@@H]1CC[C@H](Cn2cncn2)C1,,CCOC(C)=O,,,,test
US20150315183A1,C=C(CBr)C(=O)OCC.CCCN.O=C1CCC2(CC1)OCCO2>>CCCN1CC(C(=O)OCC)CC2=C1CCC1(C2)OCCO1,,Cc1ccccc1,,,,test
US20080045542A1,CC(C)(C)OC(=O)Nc1c[nH]c(C(N)=O)c1-c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)Nc1c[nH]c(C(N)=O)c1-c1ccc(N)cc1,[Pd],CO,,[H][H],,test
US20120302578A1,FC(F)(F)c1ccc(-c2cnc(Cl)o2)cc1.Nc1cccc(O)c1>>Oc1cccc(Nc2ncc(-c3ccc(C(F)(F)F)cc3)o2)c1,,CC(C)O,,,,test
US20080017846A1,O=C(Cl)c1ccccc1.c1ccc(-c2cccc(-c3nn[nH]n3)n2)cc1>>c1ccc(-c2cccc(-c3nnc(-c4ccccc4)o3)n2)cc1,,c1ccncc1,,O,[Na+].[OH-],test
US20140031338A1,C1CCOC1.CC(C)(C)OC(C(=O)[O-])C1=C(c2ccc3c(c2)CCCO3)CCCC1>>CCOC(=O)C(OC(C)(C)C)C1=C(c2ccc3c(c2)CCCO3)CCCC1,,O,,[Li+].[OH-],,test
US20030166639A1,CC(C)Cc1cc(-c2cccc(C(=O)CC(=O)Nc3cc(C(F)(F)F)c(OCC(F)(F)F)cc3NC(=O)OC(C)(C)C)c2)ccn1>>CCc1cc(-c2cccc(C3=Nc4cc(OCC(F)(F)F)c(C(F)(F)F)cc4NC(=O)C3)c2)ccn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140213578A1,NCCC=C1c2ccccc2Sc2ccccc21.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=S(=O)(NCCC=C1c2ccccc2Sc2ccccc21)c1ccc(Cl)cc1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US04927829,C1CSCCN1.CCOC(=O)c1cnc2c(SCO)cccn2c1=O>>CCOC(=O)c1cnc2c(SCN3CCSCC3)cccn2c1=O,,C1CCOC1,,O=S(=O)([O-])[O-].[Mg+2],,test
US20090111798A1,COC(=O)[C@H]1CCCC[C@H]1NC(=O)OC(C)(C)C>>COC(=O)[C@H]1CCCC[C@H]1N,,C1COCCO1,,Cc1ccccc1,Cl,test
US06150379,CCON=Cc1cc(C(=O)OC)ccn1.N=C(N)c1ccc(N)c(N)c1>>COC(=O)c1ccnc(-c2nc3cc(C(=N)N)ccc3[nH]2)c1,,CO,,Cl,,test
US20050148627A1,CCOC(=O)C1=Cc2cc(C)cc(CI)c2OC1C(F)(F)F.Nc1ccccc1>>CCOC(=O)C1=Cc2cc(C)cc(CNc3ccccc3)c2OC1C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100120841A1,O=C1Cc2ccc(F)c3cccc1c23>>OC1Cc2ccc(F)c3cccc1c23,,CO,,[BH4-].[Na+],[Cl-].[NH4+],test
US20040132694A1,NC(=O)c1c(Cl)ccc(Nc2c(Cl)c(=O)c2=O)c1O.Nc1ccc(F)cc1F>>NC(=O)c1c(Cl)ccc(Nc2c(Nc3ccc(F)cc3F)c(=O)c2=O)c1O,,CS(C)=O,,,,test
US03996219,Cn1nnnc1SCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)C(N)C2SC1>>Cn1nnnc1SCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)CC2SC1,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05496930,CC(=O)OC[C@H]1OC=C[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>CC(=O)OC[C@H]1OC=C[C@@H](O)[C@@H]1OC(C)=O,,O=P([O-])([O-])[O-],,,,test
US04057625,C=CN1CCCC1=O.C=COC(=O)CCCCCCCCCCC>>C=CN1CCCC1=O.C=COC(=O)CCCCCCCCCCC,CC(C)(C#N)N=NC(C)(C)C#N,CO,,,,test
US20140275027A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.O=S(=O)(c1ccccc1)n1c(I)cc2c(-c3cccc(F)n3)ccnc21>>CC(C)(C)OC(=O)N1CC=C(c2cc3c(-c4cccc(F)n4)ccnc3n2S(=O)(=O)c2ccccc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US20060128670A1,CCCCOC1CC(C(=O)c2ccc(OC)cc2)=NO1>>COc1ccc(C(=O)c2ccon2)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20040167176A1,CC(C)Cc1cc(-c2ccc(Cn3ccnc3)cc2)c(C(N)=O)s1.CCCCS(=O)(=O)Cl>>CCCCS(=O)(=O)NC(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20120088748A1,COCC(=O)NC[C@@H]1CN(C(=O)OC(C)(C)C)CCO[C@H]1c1ccc(Cl)c(Cl)c1.Cl>>COCC(=O)NC[C@@H]1CNCCO[C@H]1c1ccc(Cl)c(Cl)c1.Cl,,CCO,,,,test
US20080167348A1,CS(=O)(=O)c1cc(-c2ccncc2)ccc1N.O=S(=O)(Cl)c1ccc2cc(F)ccc2c1>>CS(=O)(=O)c1cc(-c2ccncc2)ccc1NS(=O)(=O)c1ccc2cc(F)ccc2c1,CN(C)c1ccncc1,ClCCl,,,,test
US20130018010A1,CC(C)[C@H](N)C(=O)O.CN(C)c1ccncc1.N#Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12.O=C(O)C(F)(F)F>>CC(C)[C@H](N)C(=O)O.N#Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12.NC(=O)[O-],CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US08492437B2,CC(C(=O)OC(C)(C)C)c1ccc(F)c(C#N)c1.ClCCl.O=C(NCCc1ccc(Cl)cc1)c1ccc(O)cc1>>CC(C(=O)OC(C)(C)C)c1ccc(Oc2ccc(C(=O)NCCc3ccc(Cl)cc3Cl)cc2)c(C#N)c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140256706A1,COC1CCC(=O)CC1.Cc1cc(NN)cc(=O)[nH]1>>COC1CCC(=NNc2cc(C)[nH]c(=O)c2)CC1,,CCO,,,,test
US05905088,CC1(C)CCC(C)(C)c2cc(I)c(O)cc21.O=C(CBr)c1ccc(Br)s1>>CC1(C)CCC(C)(C)c2cc(OCC(=O)c3ccc(Br)s3)c(I)cc21,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150299165A1,Cc1ccc(Br)c(Cl)n1.O=C1CCC1>>Cc1ccc(C2(O)CCC2)c(Cl)n1,,C1CCOC1,,O,,test
US20100272680A1,CC1(C)CN(C2CCNCC2)C(=O)O1.O=C(O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl>>CC1(C)CN(C2CCN(C(=O)c3nc4c(C(F)(F)F)cc(-c5ccoc5)cn4c3Cl)CC2)C(=O)O1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130172341A1,CC(C)(C)OC(=O)N1C2CCC(N=C=O)C1CC2.Cn1ncc2cc(-c3n[nH]c4c3CNCC4)ccc21>>Cn1ncc2cc(-c3n[nH]c4c3CN(C(=O)NC3CCC5CCC3N5C(=O)OC(C)(C)C)CC4)ccc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20100216814A1,Cc1ccc2[nH]c3c(c2c1)CN(C)CC3.c1ccc(C2(c3ccccc3)CO2)cc1>>Cc1ccc2c(c1)c1c(n2CC(O)(c2ccccc2)c2ccccc2)CCN(C)C1,,CN(C)C=O,,[H-].[Na+],,test
US20160068532A1,Cc1cc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3cc4[nH]c(=O)c(Br)cc4cc23)ccn1>>Cc1cc(-c2n[nH]c3cc4[nH]c(=O)c(Br)cc4cc23)ccn1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US05350872,COc1ccc(C=O)cc1OC.O=C1CC(=O)OC(c2ccc(F)cc2)O1>>COc1ccc(CCC(=O)O)cc1OC,,CCN(CC)CC,,O=CO,,test
US04364955,Cc1ccc(C(Cn2cncn2)=NO)c(Cl)c1.ClCc1c(Cl)cccc1Cl>>Cc1ccc(C(Cn2cncn2)=NOCc2c(Cl)cccc2Cl)c(Cl)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US06150359,CCn1c(=O)ccc2cnc(F)cc21.Nc1ccccc1>>CCn1c(=O)ccc2cnc(Nc3ccccc3)cc21,CC(=O)O,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20020037888A1,CCC1(c2cccc(OC)c2)CCCCNC1=O>>CCC1(c2cccc(OC)c2)CCCCNC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150126488A1,CN1CCC(CCN)CC1.N#Cc1nc(-c2ccc(F)c(C(F)(F)F)c2)c2cc[nH]c2n1>>CN1CCC(CCNc2ccc(-c3nc(C#N)nc4[nH]ccc34)cc2C(F)(F)F)CC1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US20160002177A1,COc1c(F)c(-c2ccc(F)cc2)c(-c2ccc(F)cc2)c2c(=O)[nH]cnc12>>O=c1[nH]cnc2c(O)c(F)c(-c3ccc(F)cc3)c(-c3ccc(F)cc3)c12,,ClCCl,,BrB(Br)Br,CO,test
US20150056141A1,CCOC(=O)c1c(NC(C)=O)sc2c(OCCN(CC)CC)c(Br)ccc12.OB(O)c1ccncc1>>CCOC(=O)c1c(NC(C)=O)sc2c(OCCN(CC)CC)c(-c3ccncc3)ccc12,,CC#N,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20110118234A1,CC(C)(C(=O)O)c1cccs1.O=C1CCC(=O)N1Br>>CC(C)(C(=O)O)c1ccc(Br)s1,,CCOC(C)=O,ClCCl,,,test
US20150353553A1,COC(=O)c1nc(N[C@H](C)C2CCC2)c2c(n1)nc(-c1cc(C(C)C)ccn1)n2C[C@@H]1CC[C@@H](C(F)(F)F)CC1>>CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2C[C@@H]2CC[C@@H](C(F)(F)F)CC2)c1,,C1CCOC1,,[Li+].[OH-],,test
US20140335018A1,CN(C)c1cccc2c(S(=O)(=O)Cl)cccc12.NCCCC[C@H](N)C(=O)O>>CN(C)c1cccc2c(S(=O)(=O)N[C@@H](CCCCN)C(=O)O)cccc12,,CN(C)C=O,,CCN(CC)CC,,test
US07312225B2,Clc1ncc(Br)c(Cl)n1.O=[N+]([O-])c1cccc(S(=O)(=O)NCCCO)c1>>O=[N+]([O-])c1cccc(S(=O)(=O)NCCCOc2nc(Cl)ncc2Br)c1,,CN(C)C=O,,[H-].[Na+],,test
US20020127428A1,CCOC(=O)c1cc2cc3c4c(c2oc1=O)CCCN4CCC3.Nc1ccccc1S>>CCN(CC)c1ccc2cc(-c3nc4ccccc4s3)c(=O)oc2c1,,Cc1ccccc1,,c1ccc(Oc2ccccc2)cc1,,test
US20020058813A1,CS(=O)(=O)N1CC2(CCNCC2)c2ccccc21.O=C(Nc1cnc(-c2ccccc2)cn1)Oc1ccccc1>>CS(=O)(=O)N1CC2(CCN(C(=O)Nc3cnc(-c4ccccc4)cn3)CC2)c2ccccc21,,CCOC(C)=O,ClC(Cl)Cl,CCN(CC)CC,Cl,test
US20050176775A1,COCCN.O=Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1-c1c(F)cccc1F>>COCCNCc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1-c1c(F)cccc1F,,ClCCl,,,,test
US05447656,Brc1cccc(OCc2ccccc2)c1.COB(OC)OC>>OB(O)c1cccc(OCc2ccccc2)c1,II,C1CCOC1,O,Cl,[Mg],test
US06350762B1,CC1=C(C(=O)O)C(c2cccc(Cl)c2)C([N+](=O)[O-])=C(C)N1.NCC=Cc1ccccc1>>CC1=C(C(=O)NCC=Cc2ccccc2)C(c2cccc(Cl)c2)C([N+](=O)[O-])=C(C)N1,,CN(C)C=O,,CCN(CC)CC,C[n+]1ccccc1Cl.[I-],test
US05491145,CN1CCN(S(=O)(=O)CCCO)CC1.Cc1cc2nccn2nc1Cl>>Cc1cc2nccn2nc1OCCCS(=O)(=O)N1CCN(C)CC1,,C1CCOC1,CN(C)C=O,O,[H-].[Na+],test
US06326369B1,CCOC(=O)c1ccc(OCCC2CCc3c(c(OC)c(OC)c(OC)c3OC)CC2)cc1>>COc1c2c(c(OC)c(OC)c1OC)CCC(CCOc1ccc(C(=O)O)cc1)CC2,,CO,,[H-].[Na+],,test
US20150353553A1,CC(C)[Mg]Br.CCOC(=O)Cl.Cc1cccnc1>>CCOC(=O)N1C=CC(C(C)C)C(C)=C1,[Cu]I,C1CCOC1,,,,test
US20140018326A1,COC(=O)N[C@H](C(=O)Nc1ccccc1CC[C@@H](CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)N(CCC(C)C)S(=O)(=O)c1ccc([N+](=O)[O-])cc1)C(c1ccccc1)c1ccccc1>>COC(=O)N[C@H](C(=O)Nc1ccccc1CC[C@@H](CO)N(CCC(C)C)S(=O)(=O)c1ccc([N+](=O)[O-])cc1)C(c1ccccc1)c1ccccc1,,C1CCOC1,CCOC(C)=O,c1ccncc1,,test
US20110224136A1,CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(-c4ccc(C(=O)O)cc4)cc3)o2)C1.Nc1ccccc1>>CC1CCCN(c2nc(C(F)(F)F)c(C(=O)Nc3ccc(-c4ccc(C(=O)Nc5ccccc5)cc4)cc3)o2)C1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120252777A1,O=[N+]([O-])c1cccc(N2C[C@@H]3CC[C@H](C2)O3)c1>>Nc1cccc(N2C[C@@H]3CC[C@H](C2)O3)c1,[Zn],C1COCCO1,O,Cl,O=C([O-])O.[Na+],test
US20090281140A1,C=CCCCCN(C)C(=O)C1CC(Oc2cc(-c3cccc(C(C)C)n3)nc3c(C)c(OC)ccc23)CC1C(=O)NC1(C(=O)OCC)CC1C=C>>CCOC(=O)C12CC1C=CCCCCN(C)C(=O)C1CC(Oc3cc(-c4cccc(C(C)C)n4)nc4c(C)c(OC)ccc34)CC1C(=O)N2,,ClCCCl,,,,test
US05776963,COc1cc(C(C)=O)ccc1OCCCl.Clc1ccc2c(C3CCNCC3)noc2c1>>COc1cc(C(C)=O)ccc1OCCC1(c2noc3cc(Cl)ccc23)CCNCC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100298287A1,CC(=O)O.CC=O.CO.Nc1ccc(Cl)c2nc3n(c12)CCCCN3c1ccc(Cl)cc1Cl>>CCc1c(CC)c(N)c2c(nc3n2CCCCN3c2ccc(Cl)cc2Cl)c1Cl,,CC(=O)O,CO,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20060189601A1,BrP(Br)Br.OCc1cc2c(cn1)OCCO2>>BrCc1cc2c(cn1)OCCO2,,ClCCl,,O=C([O-])O.[Na+],,test
US08669249B2,COC(=O)CBr.O=Cc1ccc(O)c([N+](=O)[O-])c1>>COC(=O)COc1ccc(C=O)cc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090062214A1,C=CCO[C@H]1O[C@H](CO)[C@@H](O)[C@H](OCCCCCCCCCC)[C@H]1OCC[C@H](O)CCCCCCCCCCC>>C/C=C/O[C@H]1O[C@H](CO)[C@@H](O)[C@H](OCCCCCCCCCC)[C@H]1OCC[C@H](O)CCCCCCCCCCC,,C1CCOC1,,[H][H],,test
US20150094297A1,COc1cc(O)c2cc(-c3cn4nc(OC)sc4n3)oc2c1.FC1(c2nc(CBr)cs2)CCOCC1>>COc1cc(OCc2csc(C3(F)CCOCC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1,,CN(C)C=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20100240611A1,CC(C)(O)C(C)(C)O.OB(O)N1CCCC1>>CC(C)(O)C(C)(C)O.OBO,,CC(=O)OC(C)C,,O=S(=O)([O-])[O-].[Na+].[Na+],,test
US20050065162A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCC[C@H]1CN(Cc2ccccc2)CCN1>>CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)CC1CCO,,ClCCl,,,,test
US20110160180A1,CC1CCN(C(=O)c2ccc3[nH]c4c(c3c2)CC(C2CCCCC2)CC4)CC1.CS(=O)(=O)Cl>>CC1CCN(C(=O)c2ccc3c(c2)c2c(n3S(C)(=O)=O)CCC(C3CCCCC3)C2)CC1,,C1CCOC1,,[H-].[Na+],,test
US20130041151A1,O=C(CO)c1ccccc1>>OC[C@@H](O)c1ccccc1,,CC(C)O,,CCCCCC,,test
US20130310384A1,CCN.CC[C@@H](c1ccccc1)N(Cc1ccc(C(=O)O)cc1)S(=O)(=O)c1ccc(Cl)cc1>>CCNC(=O)c1ccc(CN([C@@H](CC)c2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)cc1,,C1CCOC1,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20130196969A1,O=C(Cl)C(=O)Cl.O=C(O)c1sc2cc(C(F)(F)F)ccc2c1F>>O=C(Cl)c1sc2cc(C(F)(F)F)ccc2c1F,CN(C)C=O,ClCCl,,,,test
US20150031685A1,COC(=O)Cc1ccc2c(c1)N(Cc1ccccc1)S(=O)(=O)C2>>COC(=O)Cc1ccc2c(c1)NS(=O)(=O)C2,[Pd],CO,,[H][H],,test
US20040002513A1,Cl.O=C1C(=Cc2cccnc2)N2CCC1CC2>>Cl.O=C1C2CCN(CC2)C1Cc1cccnc1,[Pd],CO,,[H][H],,test
US06001331,CN(C)c1ccc(C=O)cc1.Cc1sc2ccccc2[n+]1Cc1ccccc1.[Br-]>>CN(C)c1ccc(/C=C/c2sc3ccccc3[n+]2Cc2ccccc2)cc1.[Br-],,CC(=O)OC(C)=O,,,,test
US04876381,CCOC(=O)c1ccc(C(C)=Cc2ccc3ccccc3c2)cc1>>CC(=Cc1ccc2ccccc2c1)c1ccc(C(=O)O)cc1,,CCO,O,[K+].[OH-],,test
US20140018393A1,CC(C)(C)OC(=O)N1CCC(C=O)CC1.N[C@@H]1C[C@H]1c1ccc(I)cc1>>CC(C)(C)OC(=O)N1CCC(CN[C@@H]2C[C@H]2c2ccc(I)cc2)CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20080194670A1,C1N2CN3CN1CN(C2)C3.CCc1cccc(C)c1O.O>>CCc1cc(C=O)cc(C)c1O,,O,,CC(=O)O,,test
US04123256,CC(C)c1ccc(COc2ccc(N=C=O)cc2)cc1.NO.O>>CC(C)c1ccc(C(=O)Oc2ccc(NC(=O)NO)cc2)cc1,,ClCCl,O,Cl,[Na+].[OH-],test
US20120059002A1,CCO.O=C(O)c1cc(O)cc(O)c1>>CCOC(=O)c1cc(O)cc(O)c1,,O,,O=S(=O)(O)O,,test
US20070270475A1,COc1cc(C(=O)N2[C@@H](c3ncc(C)s3)[C@@H](C(=O)[O-])C[C@@]2(Cc2cscn2)C(=O)OC(C)(C)C)ccc1C(C)(C)C>>COc1cc(C(=O)N2[C@@H](c3ncc(C)s3)[C@@H](CO)C[C@@]2(Cc2cscn2)C(=O)OC(C)(C)C)ccc1C(C)(C)C,,C1CCOC1,CCOCC,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100130468A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1cc(Br)cc2c(C3CC4CCC(C3)S4)c[nH]c12>>CCOC(=O)c1cc(Br)cc2c(C3CC4CCC(C3)S4)cn(C(=O)OC(C)(C)C)c12,CN(C)c1ccncc1,C1CCOC1,CC#N,,,test
US20150284395A1,CC(=O)N(C)C.COc1nn2c(=O)cc(-c3ccc(Cl)cc3)[nH]c2c1C(N)=O>>COc1nn2c(=O)cc(-c3ccc(Cl)cc3)[nH]c2c1C(=O)/N=C(\C)N(C)C,,CN(C)C=O,,CC(=O)N(C)C,,test
US20110111044A1,C1CCOC1.CC(C)(C)OC(=O)ON=C(C#N)c1ccccc1.NCCCNCCCN>>CC(C)(C)OC(=O)NCCCNCCCNC(=O)OC(C)(C)C,,C1CCOC1,,,,test
US20130045169A1,BrCCCCCCCCC1OCCO1.O=Cc1cccc(O)c1>>O=Cc1cccc(OCCCCCCCCC2OCCO2)c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130079338A1,Brc1ccc2c(cnn2C2CCCCO2)c1.Cc1ccccc1>>C=Cc1ccc2c(cnn2C2CCCCO2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,O=C([O-])[O-].[K+].[K+],,test
US20140014885A1,O=S(=O)(O)c1ccc2nc(-c3ccccc3)[nH]c2c1.O=S(Cl)Cl>>O=S(=O)(Cl)c1ccc2nc(-c3ccccc3)[nH]c2c1,,CN(C)C=O,,,,test
US20110034512A1,COC(=O)c1cc(Br)cc2c1cnn2-c1ccc(F)cc1>>O=C(O)c1cc(Br)cc2c1cnn2-c1ccc(F)cc1,,CO,O,Cl,[Na+].[OH-],test
US20090298807A1,Cc1nc(C(=O)N2CCOC3(CCN(Cc4ccc(CCO[Si](C)(C)C(C)(C)C)s4)CC3)C2)cs1>>Cc1nc(C(=O)N2CCOC3(CCN(Cc4ccc(CCO)s4)CC3)C2)cs1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100261755A1,COC(=O)C1CCNC(c2ccc(S(C)(=O)=O)cc2)C1.COC(=O)Cl>>COC(=O)C1CCN(C(=O)OC)C(c2ccc(S(C)(=O)=O)cc2)C1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US05916889,CCOC(=O)c1cccnc1N1CCNCC1.CS(=O)(=O)OCCC=C1c2ccccc2CCc2ccccc21>>CCOC(=O)c1cccnc1N1CCN(CCC=C2c3ccccc3CCc3ccccc32)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060122210A1,CC1(C)OB(c2ccc(C(=O)N3CC[C@@]4(C3)OC(=O)c3ccccc34)c(Cl)c2)OC1(C)C.O=S(=O)(Oc1ccc2cccnc2c1)C(F)(F)F>>O=C1O[C@]2(CCN(C(=O)c3ccc(-c4ccc5cccnc5c4)cc3Cl)C2)c2ccccc21,[Pd],,,,,test
US05605923,COC(=O)CCC(C#N)(CCC(=O)OC)c1ccc(OC(F)F)c(OC(F)F)c1>>COC(=O)C1CC(C#N)(c2ccc(OC(F)F)c(OC(F)F)c2)CCC1=O,,COCCOC,,[H-].[Na+],,test
US20160075692A1,Brc1cccnc1.O=C1NCCN1c1cccc2c1cnn2-c1ccccc1F>>O=C1N(c2cccnc2)CCN1c1cccc2c1cnn2-c1ccccc1F,[Cu]I,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20100130495A1,C[C@H](O)C(=O)O.OCCN(c1ccccc1)c1nc(Nc2ccc(-c3cnco3)cc2)nc2c1CNCC2>>C[C@H](O)C(=O)N1CCc2nc(Nc3ccc(-c4cnco4)cc3)nc(N(CCO)c3ccccc3)c2C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05571813,CCOC(=O)CN.CCc1cc(Cl)n2nccc2n1>>CCOC(=O)CNc1cc(CC)nc2ccnn12,,CCO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20050101643A1,CC(=O)Cl.CCC[C@@H](C)[C@@H](C)/C(N)=C/C(=O)OCC>>CCC[C@@H](C)[C@@H](C)/C(=C/C(=O)OCC)NC(C)=O,,ClCCl,,c1ccncc1,,test
US20140221332A1,C=O.O=C(O)C1CCCN1>>CN1CCCC1C(=O)O,[Pd],CO,,CC(=O)O,,test
US20050014787A1,COc1ccc(C(N)=O)cc1S(N)(=O)=O.CS(=O)(=O)OCCc1ccc(N2CCOC2=O)cc1>>COc1ccc(C(N)=O)cc1S(=O)(=O)NCCc1ccc(N2CCOC2=O)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20080119518A1,CC(C)OB(OC(C)C)OC(C)C.COc1ccc(Br)c(C)n1>>COc1ccc(B(O)O)c(C)n1,,C1CCOC1,,[Li]CCCC,,test
US20100311778A1,CC1(C)CC(N)c2ccccc2O1.CCN(CC)CC.Cl.O=C(O)/C=C/c1ccccc1-c1ccccn1>>O=C(/C=C/c1ccccc1-c1ccccn1)NC1CC2(CCC2)Oc2ccc(Cl)cc21,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20120172351A1,COC(=O)C[C@@H]1COc2cc(N(C(=O)C(F)(F)F)[C@@H]3COc4c(Nc5cc(F)ccc5N)cccc43)ccc21.Cc1cc(C(=O)Cl)no1>>COC(=O)C[C@@H]1COc2cc(N(C(=O)C(F)(F)F)[C@@H]3COc4c3cccc4-n3c(-c4cc(C)on4)nc4ccc(F)cc43)ccc21,,CC(=O)N(C)C,,O=C([O-])O.[Na+],,test
US20100305133A1,CCCC[Sn](CCCC)(CCCC)c1nccs1.CCOC(=O)CNC(=O)c1c(O)cc(Br)c2nccnc12>>O=C(O)CNC(=O)c1c(O)cc(-c2nccs2)c2nccnc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CO,[Na+].[OH-],,test
US20120289501A1,CC(=O)c1ccc(Br)cc1O.O=Cc1ccccn1>>O=C(/C=C/c1ccccn1)c1ccc(Br)cc1O,,CO,,[K+].[OH-],,test
US20050049245A1,CNCC(O)c1cc2ccccc2o1.O=C(NCc1ccc(Cl)cc1)c1cn(CCCOC2CCCCO2)c2sc(CCl)cc2c1=O>>CN(Cc1cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(CCCOC3CCCCO3)c2s1)CC(O)c1cc2ccccc2o1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030216570A1,CC(C)c1cc(Br)cc2c1OCC2(C)C.COB(OC)OC>>CC(C)c1cc(B(O)O)cc2c1OCC2(C)C,,C1CCOC1,,CCCCC,[Li]C(C)(C)C,test
US20070129347A1,CN(C)C1(c2ccccc2)CCC(CC(=O)NCc2c[nH]c3ccccc23)CC1.C[Si](C)(C)Cl>>CN(C)C1(c2ccccc2)CCC(CC(=O)NCc2c[nH]c3ccccc23)CC1.Cl,,CCC(C)=O,,,,test
US20040242572A1,CC1CCCN1.CS(=O)(=O)OCc1ccc(CCNC(=O)c2ccc(-c3ccc(Cl)cc3)cc2)cc1>>CC1CCCN1Cc1ccc(CCNC(=O)c2ccc(-c3ccc(Cl)cc3)cc2)cc1,,CCN(CC)CC,,,,test
US04791123,COc1ccc(C(C)(C=CCc2ccc(F)c(Oc3ccccc3)c2)C(F)(F)F)cc1>>COc1ccc(C(C)(CCCc2ccc(F)c(Oc3ccccc3)c2)C(F)(F)F)cc1,[Ni],CO,,[H][H],,test
US20130203775A1,CC(C)Oc1cc2c(C(=O)NCCN)c(-c3ccc(F)cc3)oc2cc1[N+](=O)[O-]>>CC(C)Oc1cc2c(C3=NCCN3)c(-c3ccc(F)cc3)oc2cc1[N+](=O)[O-],,Cc1ccccc1,,O=P(Cl)(Cl)Cl,,test
US04962225,O=C1C2CC3CC(C2)CC1C3>>OC1C2CC3CC(C2)CC1C3,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110190489A1,COc1ccc2c(c1)c(-c1cc3c(ncc4cnc(CCCNC(C)=O)n43)n1CO)cn2C>>COc1ccc2c(c1)c(-c1cc3c(ncc4cnc(CCCNC(C)=O)n43)[nH]1)cn2C,,CO,,[NH4+].[OH-],,test
US20100240656A1,BrP(Br)Br.OCCOc1cc(Br)ccc1Br>>BrCCOc1cc(Br)ccc1Br,,Cc1ccccc1,,O,,test
US20080114022A1,COC(=O)Cc1c(C)[nH]c2nccc(Cl)c12.CS(=O)(=O)c1ccc(CBr)cc1>>COC(=O)Cc1c(C)n(Cc2ccc(S(C)(=O)=O)cc2)c2nccc(Cl)c12,,CN(C)C=O,O,[H-].[Na+],,test
US20050182103A1,CC(O)c1ccc(F)cc1.Cc1ccc(-c2cc(C#N)c(Cl)nc2-c2ccc(Cl)cc2Cl)cc1>>Cc1ccc(-c2cc(C#N)c(OC(C)c3ccc(F)cc3)nc2-c2ccc(Cl)cc2Cl)cc1,,Cc1ccccc1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080194535A1,C=CCBr.O=C(N[C@H]1C[C@@H](O)c2ccc(Br)cc21)C(F)(F)F>>C=CCO[C@@H]1C[C@H](NC(=O)C(F)(F)F)c2cc(Br)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20020103123A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CN)CC1.O=S(=O)(Cl)c1cccc2ccccc12>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CNS(=O)(=O)c2cccc3ccccc23)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20160031875A1,O=[N+]([O-])c1cc(C(F)(F)F)cnc1NC1CCC1>>Nc1cc(C(F)(F)F)cnc1NC1CCC1,[Fe],CCO,,O,[Cl-].[NH4+],test
US20130172323A1,CC1CCNCC1.CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OCC=O)cc3)oc2c1>>CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OCCN4CCC(C)CC4)cc3)oc2c1,,CN(C)C=O,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20080027124A1,Fc1ccc(N2CCNCC2)cc1.NC(=O)c1[nH]c2ccc(C=O)cc2c1Sc1ccccc1>>NC(=O)c1[nH]c2ccc(CN3CCN(c4ccc(F)cc4)CC3)cc2c1Sc1ccccc1,,CO,ClCCl,,,test
US05332739,Cn1c(N2CCNCC2)cc(=O)n(C)c1=O.O=C(NCCCl)c1ccccc1>>Cl.Cn1c(N2CCN(CCNC(=O)c3ccccc3)CC2)cc(=O)n(C)c1=O,,C1COCCO1,,CCN(CC)CC,[I-].[Na+],test
US20080300246A1,Nc1ccc(Cl)c2c1oc1nc3ccncc3cc12.O=C(Cl)c1cccc(C(F)(F)F)c1>>O=C(Nc1ccc(Cl)c2c1oc1nc3ccncc3cc12)c1cccc(C(F)(F)F)c1,,CCOC(C)=O,ClCCl,,,test
US20140228322A1,COc1cc(N2CCOCC2)ccc1Nc1ncc(C(C)=O)c(Nc2ccccc2NC(=O)OC(C)(C)C)n1>>COc1cc(N2CCOCC2)ccc1Nc1ncc(C(C)=O)c(Nc2ccccc2N)n1,,ClCCl,O=C(O)C(F)(F)F,CO,,test
US20040259907A1,CCN(C(C)C)C(C)C.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CNCC(O)CCl)oc21.Nc1nnc(S)s1>>CN(Cc1cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c2o1)CC(O)CSc1nnc(N)s1,,CCO,,[Cl-].[Na+],,test
US20150266822A1,CNCc1ccncc1.Cc1ccc(-c2cc(C(=O)O)cc(C(=O)NCc3ccc(C)nc3)c2)cc1>>Cc1ccc(-c2cc(C(=O)NCc3ccc(C)nc3)cc(C(=O)N(C)Cc3ccncc3)c2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05593993,CCOc1ccc(Br)cc1CO>>CCOc1ccc(Br)cc1C=O,,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20070208054A1,CC(C)S.O=C(O)c1cc([N+](=O)[O-])ccc1F>>CC(C)Sc1ccc([N+](=O)[O-])cc1C(=O)O,,CN(C)C=O,,CCN(CC)CC,,test
US20130158006A1,COC(=O)c1cc(OC)c([N+](=O)[O-])cc1C.O=C1CCC(=O)N1Br>>COC(=O)c1cc(OC)c([N+](=O)[O-])cc1CBr,CC(C)(C#N)N=NC(C)(C)C#N,CC#N,,ClCCl,O,test
US20080058320A1,CC(C)S(=O)(=O)Cl.COCCCc1cn(C)c2ccc(CC(CC(NC(=O)OC(C)(C)C)C(O)CN)C(C)C)cc12.ClCCl>>COCCCc1cn(C)c2ccc(CC(CC(N)C(O)CNS(=O)(=O)C(C)C)C(C)C)cc12.Cl,,ClCCl,,CCN(CC)CC,,test
US20120135986A1,CS(=O)(=O)c1ccc(N)cc1.C[Si](C)(C)C#Cc1cnc2c(OS(=O)(=O)C(F)(F)F)cccn12>>C[Si](C)(C)C#Cc1cnc2c(Nc3ccc(S(C)(=O)=O)cc3)cccn12,,COCCOC,,CC(C)c1cc(C(C)C)c(-c2ccccc2P(C2CCCCC2)C2CCCCC2)c(C(C)C)c1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20060241118A1,CC=O.Cc1ccccc1N1CCN(S(=O)(=O)C[C@@H](C(=O)NO)C2CCNCC2)CC1>>CCN1CCC([C@@H](CS(=O)(=O)N2CCN(c3ccccc3C)CC2)C(=O)NO)CC1,,ClCCl,,O=C(O)C(F)(F)F,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05932599,CC(=O)Nc1ccc(S(=O)(=O)Nc2cc(Cl)nc(N)n2)cc1>>Nc1ccc(S(=O)(=O)Nc2cc(Cl)nc(N)n2)cc1,,[Na+],[OH-],,,test
US04367282,BrBr.CC(=O)NC1=NN(c2c(Cl)cc(Cl)cc2Cl)C(=O)C1>>CC(=O)NC1=NN(c2c(Cl)cc(Cl)cc2Cl)C(=O)C1Br,,CC(=O)O,,O,,test
US20060025474A1,CCC(CC)(c1ccc(O)c(C)c1)c1ccc(/C=C/C2(O)CCCC2)c(C)c1.CCOC(=O)CCCCCBr>>CCOC(=O)CCCCCOc1ccc(C(CC)(CC)c2ccc(/C=C/C3(O)CCCC3)c(C)c2)cc1C,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100305131A1,COC(=O)CCNC(=O)[C@@H](CC(=O)OC(C)(C)C)Cc1ccc(-c2ccccc2)cc1>>COC(=O)CCNC(=O)[C@@H](CC(=O)O)Cc1ccc(-c2ccccc2)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US05202321,Cc1ccc(-c2ccccc2)c[n+]1[O-].O=P(Cl)(Cl)Cl>>ClCc1ccc(-c2ccccc2)cn1,,ClCCl,,CCN(CC)CC,,test
US20080299075A1,CC(=O)NC(=N)N.O=C(CBr)c1ccc(Br)cc1>>CC(=O)Nc1ncc(-c2ccc(Br)cc2)[nH]1,,CN(C)C=O,,,,test
US20150322033A1,CI.COc1ccc(C=O)c(O)c1Br>>COc1ccc(C=O)c(OC)c1Br,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100075952A1,Cc1c(C=O)[nH]c2c1C(=O)N(C[C@@H](O)CN1CCOCC1)CCC2.Cc1cccc2c1CC(=O)N2>>Cc1cccc2c1/C(=C/c1[nH]c3c(c1C)C(=O)N(C[C@@H](O)CN1CCOCC1)CCC3)C(=O)N2,,CCO,,C1CCNCC1,,test
US04113940,CC1C=C(C(=O)OCC(Cl)(Cl)Cl)N2C(=O)C(N)[C@H]2S1>>CC1C=C(C(=O)O)N2C(=O)C(N)[C@H]2S1,[Zn],CN(C)C=O,,CC(=O)O,Cl,test
US20030045540A1,O=Cc1c(C2OCCO2)oc2ccccc12>>O=Cc1oc2ccccc2c1C=O,,O,,O=CO,,test
US20150152108A1,CC[C@@H]1CNCCO1.Clc1ccc2c(n1)N[C@H]1CCN2C1>>CC[C@@H]1CN(c2ccc3c(n2)N[C@H]2CCN3C2)CCO1,,COCCOC,O,CC(C)(C)[O-].[K+],,test
US20150232435A1,CC(C)(C)c1nc(N2CCN(CCCCN)CC2)cc(C(F)(F)F)n1.O=C(n1ccnc1)n1ccnc1.c1ccc(-c2ccccc2N2CCNCC2)cc1>>CC(C)(C)c1nc(N2CCN(CCCCNC(=O)N3CCN(c4ccccc4-c4ccccc4)CC3)CC2)cc(C(F)(F)F)n1,,CO,ClC(Cl)Cl,,,test
US05134111,CC(=O)O.CC(C)(O)c1cccc2cccc(O)c12>>C=C(C)c1cccc2cccc(OC(C)=O)c12,,CC(=O)O,,O,c1ccncc1,test
US20130274479A1,O=C(Cl)c1ccc(Cl)cc1.O=C(NO)Oc1ccccc1>>O=C(NOC(=O)c1ccc(Cl)cc1)Oc1ccccc1,,C1CCOC1,O,CCN(CC)CC,CCOC(C)=O,test
US20100249123A1,CC(C)(C#N)c1ccc(N)cc1.O=C1CCC(=O)N1Cl>>CC(C)(C#N)c1ccc(N)c(Cl)c1,,CC(C)O,,,,test
US20050245572A1,BrCCc1c[nH]c2ccccc12.COc1c(C#N)cc2ccccc2c1COCC1(c2ccc(F)cc2)CCNCC1>>COc1c(C#N)cc2ccccc2c1C(CCc1c[nH]c2ccccc12)OCC1(c2ccc(F)cc2)CCNCC1,,CS(C)=O,,O,,test
US06015827,BrCc1ccc(Br)cc1.NC(=O)c1cccc(O)c1>>NC(=O)c1cccc(OCc2ccc(Br)cc2)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20030171377A1,COC(=O)C=Cc1cccn1Cc1ccc(CCCc2nc(-c3ccccc3)oc2C)cc1>>COC(=O)CCc1cccn1Cc1ccc(CCCc2nc(-c3ccccc3)oc2C)cc1,[Pd],C1CCOC1,CO,,,test
US20110137040A1,CI.CNC(=S)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1>>CN=C(SC)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1,,CO,,,,test
US20140163219A1,O=C1CCC(=O)N1Cl.O=Cc1cc(O)ccc1O>>O=Cc1c(O)ccc(O)c1Cl,,CC#N,,O=S([O-])O.[Na+],,test
US20160159773A1,N#C[C@@H]1CCN(C2CC2)C1=O.Nc1cc(Br)cc(N)n1>>N#C[C@@]1(C2CC2)CCN(c2cc(N)nc(N)c2)C1=O,[Cu]I,COCCOC,,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US04341784,CCOC(=O)c1cn(CC)c2nc(OC)c([N+]#N)cc2c1=O.F[B-](F)(F)F>>CCOC(=O)c1cn(CC)c2nc(OC)c(F)cc2c1=O,,Cc1ccccc1C,,,,test
US20120238549A1,C1CCOC1.CC[Mg]Br.Cn1ncc2c1[C@@]1(Cc3ccccc3)CCC(=O)C[C@H]1CCC2.Cn1ncc2c1[C@]1(Cc3ccccc3)CCC(=O)C[C@@H]1CCC2>>CC[C@@]1(O)CC[C@@]2(Cc3ccccc3)c3c(cnn3C)CCC[C@H]2C1.CC[C@]1(O)CC[C@]2(Cc3ccccc3)c3c(cnn3C)CCC[C@@H]2C1,,C1CCOC1,O,CC(=O)O,,test
US20110178063A1,C1COCCN1.CCOC(=O)c1csc(C=O)n1>>CCOC(=O)c1csc(CN2CCOCC2)n1,,CO,ClCCl,O=C([O-])O.[Na+],,test
US20140296200A1,COc1nccc(-c2cnn(-c3ccc(C(=O)NCC4CCOCC4)cn3)c2OC)c1OC>>COc1nccc(-c2cnn(-c3ccc(C(=O)NCC4CCOCC4)cn3)c2O)c1OC,,CC(=O)N(C)C,,[Cl-].[Li+],,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2cccc(OC)c23)cc1.CS(=O)(=O)c1cccc(N)c1>>COc1cccc2nc(Nc3cccc(S(C)(=O)=O)c3)c3[nH]ncc3c12,C1COCCO1,CO,,Cl,,test
US06380288B1,N#C[O-].NNC(=O)c1ccccc1>>NC(=O)NNC(=O)c1ccccc1,,O,,Cl,,test
US20080051416A1,C[C@H](N)CO.Cc1c(F)cc(C(=O)O)cc1-c1ccc(C(=O)NCC(C)(C)C)cc1C(N)=O>>Cc1c(F)cc(C(=O)N[C@@H](C)CO)cc1-c1ccc(C(=O)NCC(C)(C)C)cc1C(N)=O,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120208798A1,CCOC(=O)CCc1ccc(-c2ccc3c(c2)[C@H](NC(=O)OC(C)C)C[C@H](C)N3C(C)=O)cc1>>CC(=O)N1c2ccc(-c3ccc(CCC(=O)O)cc3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C,,CO,,[Li+].[OH-],,test
US20080234270A1,CI.COC(=O)c1c[nH]c(-c2ccccc2C(F)(F)F)c1C>>COC(=O)c1cn(C)c(-c2ccccc2C(F)(F)F)c1C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US06251905B1,CC(C)(C)OC(=O)N1CCC(COS(C)(=O)=O)CC1.O=c1[nH]c2cccc3ncc1n32>>CC(C)(C)OC(=O)N1CCC(Cn2c(=O)c3cnc4cccc2n43)CC1,,CN(C)C=O,O,C1CCC2=NCCCN2CC1,,test
US20060264486A1,BrCCBr.COc1cc(C)ccc1O>>COc1cc(C)ccc1OCCBr,,CN(C)C=O,,Cl,[H-].[Na+],test
US20020012977A1,CC(C)c1ccc(S(=O)(=O)Nc2c(-c3ccc4c(c3)OCO4)c(OCCO)nn2C)nc1.CS(=O)(=O)c1ncc(Cl)cn1>>CC(C)c1ccc(S(=O)(=O)Nc2c(-c3ccc4c(c3)OCO4)c(OCCOc3ncc(Cl)cn3)nn2C)nc1,,CC(=O)N(C)C,,C1CCOC1,[H-].[Na+],test
US05166204,COc1cc2c3c4c(cc(CN(C)C)c3n(Cc3ccccc3)c2cc1Br)C(=O)N(c1ccccc1)C4=O>>COc1cc2c(cc1Br)[nH]c1c(CN(C)C)cc3c(c12)C(=O)N(c1ccccc1)C3=O,,COc1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20150148327A1,Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cncc(N)c2)c1.O=CC(=O)O>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cncc(NCC(=O)O)c2)c1,,CN(C)C=O,,O=C(O)C(F)(F)F,,test
US20090312327A1,COc1ccc(C(=O)N(C)C2CNCC2c2ccc(Cl)cc2)cc1C(F)(F)F.O=C(Cl)c1ccc(F)cc1>>COc1ccc(C(=O)N(C)C2CN(C(=O)c3ccc(F)cc3)CC2c2ccc(Cl)cc2)cc1C(F)(F)F,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US06537948B1,COC(=O)COc1ncccc1Oc1cc(NC(C)=O)c(F)cc1[N+](=O)[O-]>>COC(=O)COc1ncccc1Oc1cc(NC(C)=O)c(F)cc1N,[Fe],CC(=O)O,CCOC(C)=O,O,,test
US20100216986A1,CC(C)[Si](Cl)(C(C)C)C(C)C.Oc1ccc(-c2ccc[se]2)cc1>>CC(C)[Si](Oc1ccc(-c2ccc[se]2)cc1)(C(C)C)C(C)C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US20110046133A1,COC(=O)c1ccc(N)c(N)c1.O=Cc1c(Cl)cccc1C(F)(F)F>>COC(=O)c1ccc2nc(-c3c(Cl)cccc3C(F)(F)F)[nH]c2c1,,CS(C)=O,,O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3],,test
US06369057B1,C[C@H](N)C(=O)O.O=[N+]([O-])c1ccc(Cl)cc1Cl>>C[C@H](Nc1cc(Cl)ccc1[N+](=O)[O-])C(=O)O,,COCCO,,[Na+].[OH-],,test
US20060069096A1,C[C@@H](O)Cn1ncc2ccc(O)c(Br)c21.O=N[O-]>>C[C@@H](O)Cn1ncc2ccc(O)c([N+](=O)[O-])c21,,C1CCOC1,CC(=O)O,O,,test
US20160158207A1,CC(O)c1ccn(C)n1.O=S(Cl)Cl>>CC(Cl)c1ccn(C)n1,,ClCCl,,,,test
US04699649,COc1nc(C)nc(NC(=O)Oc2ccccc2)n1.CSc1nnc(-c2ccccc2CS(N)(=O)=O)o1>>COc1nc(C)nc(NC(=O)NS(=O)(=O)Cc2ccccc2-c2nnc(SC)o2)n1,,C1COCCO1,O,C1CCC2=NCCCN2CC1,Cl,test
US09296736B2,C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CC)CO)C1=O>>C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](C=O)CC)C1=O,,ClCCl,,O,,test
US20050272778A1,BrCc1ccc(-c2ccccc2)cc1.c1ccc(Cn2nnc3ccccc32)cc1>>c1ccc(-c2ccc(CC(c3ccccc3)n3nnc4ccccc43)cc2)cc1,,C1CCOC1,,[Li]CCCC,,test
US04785090,NOCc1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1.O=C(O)C(=O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>O=C(O)/C(=N\OCc1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,CO,,,,test
US20100317651A1,C1=C(c2cnc3c(n2)OCCN(Cc2ccccc2)C3)CCC1.CC(Cl)OC(=O)Cl>>C1=C(c2cnc3c(n2)OCCNC3)CCC1.Cl,,Cc1ccccc1,,,,test
US04638068,CC(C)C(C)(C#N)NC(=O)/C=C\C(=O)O>>CC(C)C(C)(C#N)N1C(=O)C=CC1=O,,CC(=O)OC(C)=O,,CC(=O)[O-].[Na+],,test
US20080312226A1,Cc1noc(N)c1C.O=C(Cl)OCC(Cl)(Cl)Cl>>Cc1noc(NC(=O)OCC(Cl)(Cl)Cl)c1C,,C1CCOC1,,O,c1ccncc1,test
US20020142971A1,CCCCCC.CCOC(C)=O.CN(C)C=O.Cc1c(-c2ccc(OCc3ccccc3)cc2)[nH]c2ccc(OCc3ccccc3)cc12.ClCc1ccccc1.O>>Cc1c(-c2ccc(OCc3ccccc3)cc2)n(Cc2ccc(OCCN3CCCCCC3)cc2)c2ccc(OCc3ccccc3)cc12,,O,,[H-].[Na+],,test
US04952601,Fc1cc(C(F)(F)F)cc(F)c1F.N>>Nc1c(F)cc(C(F)(F)F)cc1F,,C1CCOC1,,,,test
US20100324302A1,CC(=Cc1csc(C)n1)C1CC2C(CCCC(C)C(O)C(C)C(=O)C(C)(C)C(O)CC(=O)O1)N2CCO.O=C([O-])OCC(SSc1ccccn1)n1nnc2ccccc21>>C/C(=C\c1csc(C)n1)[C@@H]1C[C@H]2[C@@H](CCC[C@H](C)[C@H](O)[C@@H](C)C(=O)C(C)(C)[C@@H](O)CC(=O)O1)N2CCOC(=O)OCCSSc1ccccn1,CN(C)c1ccncc1,ClCCl,,,,test
US04582833,CSC(=NC#N)SC.NN.c1cc(CN2CCNCC2)ccn1>>Nc1nnc(N2CCN(Cc3ccncc3)CC2)[nH]1,,CCO,,O,,test
US04243609,CCCCCCCCCCCCCCCCNc1ccc(C(=O)Cl)c(F)c1.CCOC(=O)CC(=O)OCC>>CCCCCCCCCCCCCCCCNc1ccc(C(=O)C(C(=O)OCC)C(=O)OCC)c(F)c1,,COCCOC,,Cl,[H-].[Na+],test
US20100048581A1,COc1ccc(C(C[N+](=O)[O-])c2ccccc2)cc1>>COc1ccc(C(CN)c2ccccc2)cc1,[Ni],CO,,,,test
US20100305096A1,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C=O)n(C)c2n1.F[C@H]1CCN(C2CCNCC2)C1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(N4CC[C@H](F)C4)CC3)n(C)c2n1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100331306A1,CC(NC(=O)OC(C)(C)C)c1nc2cccc(C#N)c2cc1-c1ccccn1>>CC(N)c1nc2cccc(C#N)c2cc1-c1ccccn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110160198A1,COC(=O)[C@H](Cc1ccc2c(c1)OC[C@H](c1ccc(OCc3ccc(Cl)c(Cl)c3)cc1)O2)NC(=O)OC(C)(C)C.ClCCl>>COC(=O)[C@@H]1Cc2cc3c(cc2CN1C(=O)OC(C)(C)C)O[C@@H](c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1)CO3,,C1COCCO1,,,,test
US20090137595A1,CC#CC(=O)O.CC(=O)N(C)C.Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)ccc1F>>CC#CC(=O)Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)ccc1C,,C1CCOC1,CC(=O)N(C)C,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20040019033A1,CNOC.O=C(O)c1cc(Cl)cc(OC(F)F)c1>>CON(C)C(=O)c1cc(Cl)cc(OC(F)F)c1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20090197862A1,COC(=O)C(OC)OC.NCc1cccc(F)c1Cl>>COC(OC)C(=O)NCc1cccc(F)c1Cl,,CCOC(C)=O,,CCN(CC)CC,CO,test
US05739132,CCCCS(=O)(=O)NC1Cc2ccc(C3=NNC(=O)CC3)cc2C1>>CCCCS(=O)(=O)NC1Cc2ccc(-c3ccc(=O)[nH]n3)cc2C1,,CS(C)=O,,Br,CC(=O)O,test
US20040209932A1,Cc1cccc(-c2nc(CO[C@H]3CCC[C@@H](OCc4ccccc4B4OC(C)(C)C(C)(C)O4)C3)c(C)o2)c1>>Cc1cccc(-c2nc(CO[C@H]3CCC[C@@H](OCc4ccccc4B(O)O)C3)c(C)o2)c1,,C1CCOC1,,Cl,,test
US20140243368A1,Cc1nc(C(=O)O)c(-c2ccccc2)s1.O=C(Cl)C(=O)Cl>>Cc1nc(C(=O)Cl)c(-c2ccccc2)s1,,ClCCl,,CN(C)C=O,,test
US05716948,COc1ccc(COC(=O)C(O)N2C(=O)[C@@H](N3C(=O)c4ccccc4C3=O)[C@H]2CCC(=O)[C@@H]2CCCO2)cc1.O=S(Cl)Cl>>COc1ccc(COC(=O)C(Cl)N2C(=O)[C@@H](N3C(=O)c4ccccc4C3=O)[C@H]2CCC(=O)[C@@H]2CCCO2)cc1,,C1CCOC1,,Cc1cccc(C)n1,,test
US20040235836A1,CC(C)N(C)[C@@H]1CC[C@H](NC(=O)CC(=O)Nc2cc(C(F)(F)F)ccc2NC(=O)OC(C)(C)C)[C@H](CS(=O)(=O)c2ccccc2)C1>>CC(C)N(C)[C@@H]1CC[C@H](NC(=O)CC(=O)Nc2cc(C(F)(F)F)ccc2N)[C@H](CS(=O)(=O)c2ccccc2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04625047,CCOC(=O)CC(C)=O.O=C(O)COc1ccc(C(=O)C=Cc2ccccc2)c(Cl)c1Cl>>O=C(O)COc1ccc(C2=CC(=O)CC(c3ccccc3)C2)c(Cl)c1Cl,,CCO,,[Na],,test
US20050020587A1,CC(=O)N1CCC(N)C1.CSc1cccc(Oc2ncc(F)cc2C(=O)O)c1>>CSc1cccc(Oc2ncc(F)cc2C(=O)NC2CCN(C(C)=O)C2)c1,CN(C)c1ccncc1,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20050020652A1,CCOC(=O)C(C)(Cc1ccc(OCCC2CN(Cc3ccccc3)C(=O)N2C)cc1)Oc1ccccc1F>>CN1C(=O)N(Cc2ccccc2)CC1CCOc1ccc(CC(C)(Oc2ccccc2F)C(=O)O)cc1,,CCO,,[Na+].[OH-],,test
US04866076,COC(=O)c1ccccc1CBr.O=S(=O)(Nc1cccc(Cl)c1)c1ccc2c(c1)CNCC2>>COC(=O)c1ccccc1CN1CCc2ccc(S(=O)(=O)Nc3cccc(Cl)c3)cc2C1,,CC#N,,CCN(CC)CC,Cl,test
US20030055244A1,CCOC(=O)CCN1CCN(C(=O)N2CCC3(CCN(c4ccncc4)CC3)C2)CC1=O>>O=C(O)CCN1CCN(C(=O)N2CCC3(CCN(c4ccncc4)CC3)C2)CC1=O,,C1COCCO1,,[Na+].[OH-],,test
US20140155413A1,CC(C)(C)Oc1ccc(OCCO)cc1.COC(=O)c1cc2c(Cl)nccc2[nH]1>>COC(=O)c1cc2c(Cl)nccc2n1CCOc1ccc(OC(C)(C)C)cc1,,Cc1ccccc1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06380218B1,CC(=O)c1cccc(Oc2ncccc2C(=O)O)c1.C[C@H](O)C1CCC(CN)CC1>>CC(=O)c1cccc(Oc2ncccc2C(=O)NCc2ccc([C@H](C)O)cc2)c1,,ClC(Cl)Cl,,,,test
US20100061936A1,CCOP(=O)(Cl)OCC.Cc1ccc(O)c(C=O)c1>>CCOP(=O)(OCC)Oc1ccc(C)cc1C=O,,CCN(CC)CC,ClCCl,Cl,,test
US20110039840A1,NOC1CCCCO1.O=C(O)/C=C/c1ccc2c(c1)C(=O)CC1(CCN(CCc3ccccc3F)CC1)O2>>O=C(/C=C/c1ccc2c(c1)C(=O)CC1(CCN(CCc3ccccc3F)CC1)O2)NOC1CCCCO1,,ClCCl,,,,test
US20040082780A1,CC(C)(C)OC(=O)Nc1cc(C(F)(F)F)ccc1-c1cc(Oc2ccc3cccnc3c2)ncn1>>Nc1cc(C(F)(F)F)ccc1-c1cc(Oc2ccc3cccnc3c2)ncn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020119983A1,COc1ccccc1N1CCNCC1.O=CCCc1cc(-c2ccccc2)no1>>COc1ccccc1N1CCN(CCCc2cc(-c3ccccc3)no2)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090012103A1,CCOC(=O)CC(C)=O.Nc1nnn[nH]1.O=Cc1cccc2ccccc12>>CCOC(=O)C1=C(C)Nc2nnnn2C1c1cccc2ccccc12,,CCO,,CCN(CC)CC,,test
US20020072528A1,COc1ccc2c(O)c([N+](=O)[O-])cnc2c1.Cl>>COc1ccc2c(O)c(N)cnc2c1.Cl,[Pd],CCOCC,CO,[NH4+].[OH-],,test
US06881733B1,C=CC(=O)OC.NCc1ccccc1>>COC(=O)CCNCc1ccccc1,,CO,,,,test
US07893261B2,OC(CCN1CCN(c2ccccc2)CC1)c1ccccc1.Oc1ccc(C(F)(F)F)cc1>>Fc1ccc(OC(CCN2CCN(c3ccccc3)CC2)c2ccccc2)cc1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110301161A1,Cc1cn[nH]c1.O=Cc1ccccc1F>>Cc1cnn(-c2ccccc2C=O)c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04391812,C=O.N#CCC(=O)O.OCC1CCCNC1>>C=C(C#N)CN1CCCC(CO)C1,,C1COCCO1,,,,test
US20120053173A1,CCCCCCC(Nc1ccc(C(=O)OC)cc1)c1cc2cc(Cl)ccc2n1C>>CCCCCCC(Nc1ccc(C(=O)O)cc1)c1cc2cc(Cl)ccc2n1C,,CCO,,C1CCOC1,[Na+].[OH-],test
US20050288314A1,CC(C)(C)C=O.Clc1ccc([Mg]Br)cc1>>CC(C)(C)C(O)c1ccc(Cl)cc1,,CCOCC,,,,test
US20110039831A1,CC(=O)N1CCNCC1.Cn1ncc2c(F)c(Cc3cnc4ccc(Cl)nn34)c(F)cc21>>CC(=O)N1CCN(c2ccc3ncc(Cc4c(F)cc5c(cnn5C)c4F)n3n2)CC1,,CCOC(C)=O,CN1CCCC1=O,[F-].[K+],,test
US20160052951A1,CCC1=C(C)C(=O)OC(C)(C)O1.C[Si](C)(C)Cl>>C/C=C1\OC(C)(C)OC(O[Si](C)(C)C)=C1C,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20070191604A1,COC(=O)C1(C(C)OC(C)=O)CCN(Cc2ccccc2)C1>>COC(=O)C1(C(C)O)CCN(Cc2ccccc2)C1,,CO,,Cl,,test
US20090036495A1,CN(C)C=O.O=C(O)c1cc(F)cnc1Cl.Oc1ccc(F)cc1>>COC(=O)c1cc(F)cnc1Oc1ccc(F)cc1,[Cu],CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070003539A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1nccc2cc(N(Cc3ccccc3)Cc3ccccc3)cc(F)c12>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nccc2cc(N(Cc3ccccc3)Cc3ccccc3)cc(F)c12,CN(C)c1ccncc1,CC#N,,,,test
US20060257987A1,CCCCc1ccc(OC(C)CCOc2ccc(CCC(=O)OC)c(C)c2)c(C(=O)c2ccccc2)c1>>CCCCc1ccc(OC(C)CCOc2ccc(CCC(=O)O)c(C)c2)c(C(=O)c2ccccc2)c1,,CO,O,Cl,[Na+].[OH-],test
US20140213586A1,COc1cncc(N)c1.O=Cc1ccc(F)cc1>>COc1cncc(N=Cc2ccc(F)cc2)c1,,CCO,,,,test
US20040162331A1,COCCl.Oc1cccc(I)c1>>COCc1cccc(I)c1,,CC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040067955A1,CC(C)n1nc(-c2cc(C(N)=S)c(N)nc2-c2ccccc2)ccc1=O.O=C(CBr)c1ccccc1>>CC(C)n1nc(-c2cc(-c3nc(-c4ccccc4)cs3)c(N)nc2-c2ccccc2)ccc1=O,,C1COCCO1,,O,O=C([O-])O.[Na+],test
US20070293526A1,CN(Cc1cccc2cc(S(=O)(=O)c3ccccc3)ccc12)C(=O)OC(C)(C)C>>CNCc1cccc2cc(S(=O)(=O)c3ccccc3)ccc12,,CCOCC,,Cl,,test
US20070179151A1,COc1cc(CC#N)c(C(=O)O)c(OC)c1.Cc1cc(N)n[nH]1>>COc1cc(OC)c2c(O)nc(Nc3cc(C)[nH]n3)cc2c1,,CC(=O)O,,,,test
US20110046110A1,Nc1nccs1.O=C(O)c1cccc2cnc(-c3cccnc3)nc12>>O=C(Nc1nccs1)c1cccc2cnc(-c3cccnc3)nc12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060199817A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(N3CCOCC3)nncc2c1>>Cc1ccc(C(=S)NC2CC2)cc1-c1ccc2c(N3CCOCC3)nncc2c1,,C1CCOC1,,,,test
US20070066658A1,CC(=O)c1ccc(Oc2ccc(CCNCc3ccccc3)cc2)cc1.O=C(OO)c1cccc(Cl)c1>>CC(=O)Oc1ccc(Oc2ccc(CCNCc3ccccc3)cc2)cc1,,ClC(Cl)Cl,ClCCl,,,test
US04046636,O=C1Nc2ccc(Cl)cc2C(c2ccccc2)=NC1O.O=S(Cl)Cl>>O=C1Nc2ccc(Cl)cc2C(c2ccccc2)=NC1Cl,,CN(C)C=O,,,,test
US20090318428A1,CI.CN(C)C=O.N#CCc1cccc(Br)c1>>CC(C)(C#N)c1cccc(Br)c1,,CCOCC,,[H-].[Na+],,test
US20070185184A1,CC(=O)c1cn(-c2ccc(C(N)=O)cc2Cl)c2ccccc12.NO>>CC(=NO)c1cn(-c2ccc(C(N)=O)cc2Cl)c2ccccc12,,CO,,CCN(CC)CC,Cl,test
US20100256357A1,CN(C)C=NS(=O)(=O)c1ccc(CO)c(F)c1>>CN(C)C=NS(=O)(=O)c1ccc(C=O)c(F)c1,O=[Mn]=O,C1CCOC1,,,,test
US20050256172A1,C(=NC1CCCCC1)=NC1CCCCC1.CNCC(O)c1cccnc1.O=C(O)Cc1ccc(Cl)c(Cl)c1>>CCCN(CC(O)c1cccnc1)C(=O)Cc1ccc(Cl)c(Cl)c1,,ClCCl,,,,test
US20100144700A1,CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCC1NC(C)c1ccccc1>>CC(NC1CCN(C(=O)OC(C)(C)C)CC1CO)c1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06656660B1,C1=COCCC1.C1COCCO1.Cc1ccc(S(=O)(=O)[O-])cc1.O.c1cc[nH+]cc1>>C=Cc1ccc(O)cc1.C=Cc1ccc(OC2CCCCO2)cc1,,C1COCCO1,,,,test
US20110015225A1,CC1(C)OB(/C=C/C2CC2)OC1(C)C.CCOC(=O)c1ccc(I)cc1>>CCOC(=O)c1ccc(/C=C/C2CC2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,[Na+].[OH-],test
US20110237573A1,CCCC[Sn](CCCC)(CCCC)c1ccnc(C)c1.COC(=O)Cc1ccnc(Cl)c1>>COC(=O)Cc1ccnc(-c2ccnc(C)c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,CN(C)C=O,,test
US04929637,COCCOCOC(C)c1cc(S(N)(=O)=O)sc1S(C)(=O)=O>>CC(O)c1cc(S(N)(=O)=O)sc1S(C)=O,,CO,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US20150315198A1,O=Cc1ccc(N2CCOC2=O)nc1>>O=C1OCCN1c1ccc(CO)cn1,,C1CCOC1,,[BH4-].[Na+],,test
US04207320,C1CNC1.CCc1ccc2c(ccc3n4c(ccc5cc(F)ccc54)c[n+]23)c1.[I-]>>CCc1ccc2c(ccc3n4c(ccc5cc(N6CCC6)ccc54)c[n+]23)c1.[I-],,CN(C)C=O,,,,test
US20060030613A1,CC(C)(C)c1ccc(C=O)c(O)c1.NCCc1ccc(F)cc1>>CC(C)(C)c1ccc(CNCCc2ccc(F)cc2)c(O)c1,,CO,,[BH4-].[Na+],,test
US20080096921A1,CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CCCO.COC(=O)c1ccc2cc(-c3ccc(O)cc3)ccc2n1>>COC(=O)c1ccc2cc(-c3ccc(OCCCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3)ccc2n1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100120806A1,CC(C)(C)OC(=O)c1cc(Cl)ccn1.Nc1ccc(O)cc1>>CC(C)(C)OC(=O)c1ccc(Oc2ccc(N)cc2)cn1,,CN(C)C=O,,[H-].[Na+],,test
US20140080798A1,COC(=O)Cc1ccc(C(F)(F)F)cc1C#Cc1nc(Nc2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc2)ncc1C(F)(F)F>>COC(=O)Cc1ccc(C(F)(F)F)cc1CCc1nc(Nc2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc2)ncc1C(F)(F)F,[Pd],CCN(CC)CC,CN(C)C=O,,,test
US20150087646A1,COC(=O)c1ccc(-n2nc(-c3cc(S(=O)(=O)NC4CC4)ccc3Cl)[nH]c2=O)cc1OC.Nc1cccc(C(F)(F)F)c1>>COc1cc(-n2nc(-c3cc(S(=O)(=O)NC4CC4)ccc3Cl)[nH]c2=O)ccc1C(=O)Nc1cccc(C(F)(F)F)c1,,Cc1ccccc1,,C[Al](C)C,,test
US06265575B1,CN(C)c1cc2ccccc2s1.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CN(C)c1sc2ccccc2c1C(=O)c1ccc([N+](=O)[O-])cc1,,Clc1ccccc1,,,,test
US20130131034A1,CC(=O)OC(C)=O.[O-][n+]1cccc2c1CCC2>>CC(=O)OC1CCc2cccnc21,,CCOCC,,O,,test
US20100035902A1,CC(=O)C(=Cc1cccc2c(=O)cc(C)oc12)C(C)=O.Nc1cc(O)nc(N)n1>>CC(=O)C1=C(C)Nc2nc(N)nc(O)c2C1c1cccc2c(=O)cc(C)oc12,,CC(C)O,,,,test
US05591503,CCCCCCCCCCCCN.O=S(=O)(Cl)c1ccccc1>>CCCCCCCCCCCCNS(=O)(=O)c1ccccc1,,Cc1ccccc1,,CCN(CC)CC,,test
US06329370B1,COc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1C#Cc1ccccc1>>COc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1C=Cc1ccccc1,[Pd],C1CCOC1,,,,test
US20130231328A1,CC(C)(C)OC(=O)NC1CCC(Oc2ncnc3sc4c(c23)C[C@@H](CC(N)=O)CC4)CC1.Cl>>Cl.NC(=O)C[C@H]1CCc2sc3ncnc(OC4CCC(N)CC4)c3c2C1,,ClCCl,,,,test
US04017631,CI.Clc1ccc(COC(Cn2ccnc2)c2ccccc2)cc1>>Cn1cc[n+](CC(OCc2ccc(Cl)cc2)c2ccccc2)c1.[I-],,CCOCC,,CC#N,,test
US20060281757A1,CC(C)(C)OC(=O)N1CCN(c2cccc(S(=O)(=O)c3ccccc3)c2Cl)CC1>>O=S(=O)(c1ccccc1)c1cccc(N2CCNCC2)c1Cl,,C1COCCO1,,,,test
US05110820,COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCCCCN)C1c1cccc(C(F)(F)F)c1.c1ccc(OCC2CO2)cc1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCCCCNCC(O)COc2ccccc2)C1c1cccc(C(F)(F)F)c1,,CO,,,,test
US05405861,CC1OC1(Cn1cncn1)c1ccc(F)cc1F.COC(=O)CCS>>CC(S)C(O)(Cn1cncn1)c1ccc(F)cc1F,,CO,O,Cl,C[O-].[Na+],test
US20070111998A1,CNCC(O)COc1cccc2[nH]c3ccccc3c12.COc1cc(C=O)cc(OC)c1>>COc1cc(CN(C)CC(O)COc2cccc3[nH]c4ccccc4c23)cc(OC)c1,CC(=O)O,,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05604237,CSc1ccc(Nc2ccccc2C(=O)O)c(C(=O)O)c1>>CSc1cc(C(=O)O)c2[nH]c3ccccc3c(=O)c2c1,,O=P(Cl)(Cl)Cl,,O,,test
US20080280876A1,CCOC(=O)c1c(C)nc2cnccn12>>Cc1nc2cnccn2c1C(=O)O,,O,,Cl,[Na+].[OH-],test
US20060025474A1,CCC(CC)(c1ccc(O)c(C)c1)c1ccc(CCC(O)C(C)(C)C)c(C)c1.CCOC(=O)CCCCCCBr>>CCC(CC)(c1ccc(CCC(O)C(C)(C)C)c(C)c1)c1ccc(OCCCCCCC(=O)O)c(C)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060040940A1,Cn1cnc(COc2cccc(B3OCC(C)(C)CO3)c2)n1.FC(F)(F)c1cnn2c(Br)cnc2n1>>Cn1cnc(COc2cccc(-c3cnc4nc(C(F)(F)F)cnn34)c2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20150073146A1,CCCSc1nc(Cl)c(N)c(N[C@@H]2C[C@H](OCCO)[C@H]3OC(C)(C)O[C@@H]23)n1.O=N[O-]>>CCCSc1nc(Cl)c2nnn([C@@H]3C[C@H](OCCO)[C@H]4OC(C)(C)O[C@H]43)c2n1,,CCOC(C)=O,O,CC(=O)O,,test
US04225337,Cc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2[N+](=O)[O-])n1>>Cc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2N)n1,[Pd],CCO,,[H][H],,test
US20060173188A1,COC(=O)c1ccc(N)cc1.O=C(O)COCCCl.c1ccncc1>>CCOC(=O)c1ccc(NC(=O)COCCCl)cc1,,ClCCl,,CN(C)C=O,O=S(Cl)Cl,test
US20110136780A1,CCC1(N)CCN(C(=O)OC(C)(C)C)CC1.COC(=O)c1ccnc2c1c(C=O)cn2C(=O)OC(C)(C)C>>CCC1(NCc2cn(C(=O)OC(C)(C)C)c3nccc(C(=O)OC)c23)CCN(C(=O)OC(C)(C)C)CC1,CC(=O)O,CO,,[BH3-]C#N.[Na+],,test
US20150057265A1,CC(C)(C)OC(=O)Nc1oc2cc(C3CCOCC3)cnc2c1C(=O)Nc1cnccc1N1C[C@H](C(F)(F)F)C[C@H](NC(=O)OC(C)(C)C)C1>>Nc1oc2cc(C3CCOCC3)cnc2c1C(=O)Nc1cnccc1N1C[C@H](C(F)(F)F)C[C@H](N)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100121048A1,Cc1c(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2Cc2ccccc2)ccn1-c1ccc([N+](=O)[O-])cc1>>Cc1c(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2Cc2ccccc2)ccn1-c1ccc(N)cc1,[Pd],CO,,,,test
US20040110742A1,CN(C)c1ccc(CCN2CC[C@@H](N3c4ccc(F)cc4COc4ccccc43)C2)cc1.Cl.ClCCl>>CN(C)c1ccc(CCN2CC[C@@H](N3c4ccc(F)cc4COc4ccccc43)C2)cc1.Cl.Cl,,ClCCl,,CCOC(C)=O,,test
US20070129354A1,CN(C)CCCl.COC(=O)c1ccc(I)c(O)c1>>COC(=O)c1ccc(I)c(OCCN(C)C)c1,,CN(C)C=O,,[H-].[Na+],,test
US08519142B2,N#Cc1ccc(-c2cncc(N)c2)cc1Cl.O=S(=O)(Cl)Cc1ccccc1Cl>>N#Cc1ccc(-c2cncc(NS(=O)(=O)Cc3ccccc3Cl)c2)cc1Cl,,c1ccncc1,,,,test
US20030073846A1,CC(C)(C)OC(=O)N1[C@@H](Cc2ccc(O)c(Cl)c2)COC1(C)C.Cl>>Cl.N[C@H](CO)Cc1ccc(O)c(Cl)c1,,C1COCCO1,CO,,,test
US20040019059A1,N#Cc1ccc(C2(c3ccccc3)OC=CCO2)cc1.NO>>NC(=NO)c1ccc(C2(c3ccccc3)OCCO2)cc1,,CCO,,CCN(CC)CC,,test
US07238714B2,COC(=O)c1cc(Cl)ccc1Oc1cncc(F)c1>>O=C(O)c1cc(Cl)ccc1Oc1cncc(F)c1,,CO,,Cl,[Na+].[OH-],test
US20150266824A1,Cc1cscc1Br.O=C=O>>Cc1cscc1C(=O)O,,C1CCOC1,,[Li]CCCC,,test
US04447603,CCCc1nc(C(C)=O)c(C)[nH]1.CCOC(=O)NN>>CCCc1nc(C)c2c(C)n[nH]c(=O)n12,CC(=O)O,CCCCO,,,,test
US20090162283A1,N.S=C=Nc1ccc(Br)cc1>>NC(=S)Nc1ccc(Br)cc1,,C1CCOC1,,,,test
US20100311748A1,O=C(Cl)C(=O)Cl.O=C(O)c1ccc(OCc2ccccn2)cc1>>O=C(Cl)c1ccc(OCc2ccccn2)cc1,CN(C)C=O,C1CCOC1,,,,test
US20100273764A1,COc1cnc(Cl)c(B(O)O)c1.Cc1nc(N)nc(Cl)n1>>COc1cnc(Cl)c(-c2nc(C)nc(N)n2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20090018148A1,CCCCn1c(SC(CC)C(=O)OCC)nc2c1c(=O)[nH]c(=O)n2C.N>>CCCCn1c(SC(CC)C(N)=O)nc2c1c(=O)[nH]c(=O)n2C,,CO,,,,test
US20060241142A1,CC(C)(C)OC(=O)N1CCC(CN)(c2ccc(Cl)cc2)CC1.CN1CCOCC1.COc1c(C#N)cc2ccccc2c1C(=O)O.ClCCl.On1nnc2ccccc21>>CCN=C=NCCCN(C)C.COc1c(C#N)cc2ccccc2c1C(=O)NCC1(c2ccc(Cl)cc2)CCN(C(=O)OC(C)(C)C)CC1.Cl,,ClCCl,,O,,test
US05883134,CCC(C[N+](=O)[O-])OC(C)=O.CCS>>CCSC(CC)C[N+](=O)[O-],,CC#N,,CCN(CC)CC,Cl,test
US04877443,COCCCN.Fc1nc(NC2CC2)cc(C(F)(F)F)n1>>COCCCNc1nc(NC2CC2)cc(C(F)(F)F)n1,,C1CCOC1,,ClCCl,,test
US20080207654A1,CCCCc1nc(C)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.OCc1cnc(-c2ccccc2)s1>>CCCCc1nc(C)n(Cc2cnc(-c3ccccc3)s2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1,,C1CCOC1,CCOC(C)=O,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US03931195,CI.COc1ccc(C(=O)Nc2ccccc2Cc2ccccn2)cc1>>COc1ccc(C(=O)Nc2ccccc2Cc2cccc[n+]2C)cc1.[I-],,CC(C)=O,,,,test
US20120196884A1,CC1(C)OCC(CN)O1.O=[N+]([O-])c1ccc(F)cc1>>CC1(C)OCC(CNc2ccc([N+](=O)[O-])cc2)O1,,CCO,,CCN(CC)CC,,test
US06087380,Cn1c(COc2ccc(C#N)cc2)nc2nc(C=O)ccc21.OO>>Cn1c(COc2ccc(C#N)cc2)nc2nc(C(=O)O)ccc21,,O=CO,,,,test
US05117000,CC(C)c1ccc(C(N)=O)cc1.CC1OC(C)OC(C)O1.O=CO.c1ccsc1>>CC(C)c1ccc(C(=O)NC(C)c2cccs2)cc1,,O=CO,,O=P(O)(O)O,,test
US20120142732A1,Cc1cnc(N)cc1-c1nc(-c2nncn2COCC[Si](C)(C)C)c(-c2ccccc2Cl)o1.O=C(Cl)C1CC1>>Cc1cnc(NC(=O)C2CC2)cc1-c1nc(-c2nnc[nH]2)c(-c2ccccc2Cl)o1,,ClCCl,,CO,,test
US05556863,CCCC(=O)c1cnc2c(OCCCSC)cccc2c1Nc1ccccc1Cl.[O-]Cl>>CCCC(=O)c1cnc2c(OCCCS(C)=O)cccc2c1Nc1ccccc1Cl,,ClCCl,,O,,test
US20130150344A1,CI.O=C1Nc2ccc([N+](=O)[O-])c(F)c2C12CCC2>>CN1C(=O)C2(CCC2)c2c1ccc([N+](=O)[O-])c2F,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20040220192A1,CC(=O)Cl.Nc1cccc(N2CCN(CCCCNS(=O)(=O)C3CCCCC3)CC2)c1>>CC(=O)Nc1cccc(N2CCN(CCCCNS(=O)(=O)C3CCCCC3)CC2)c1,,ClCCl,,,,test
US06197729B1,O=C(c1ccc(OCc2ccccc2)cc1)C(F)(F)F>>OC(c1ccc(OCc2ccccc2)cc1)C(F)(F)F,,CCO,O,[BH4-].[Na+],,test
US20060069123A1,CCOC(=O)C(C1CCN(C(=O)OC(C)(C)C)CC1)N1CCC(=O)CC1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)C(C1CCN(C(=O)OC(C)(C)C)CC1)N1CC=C(OS(=O)(=O)C(F)(F)F)CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05981533,CC(=O)Nc1ccc(CNc2n[nH]c(N)c2C#N)cc1.CCOC(OCC)N(C)C>>CC(=O)Nc1ccc(CNc2n[nH]c(N=CN(C)C)c2C#N)cc1,,Cc1ccccc1,,,,test
US20050222204A1,COC(=O)c1cccc(C2(C)CCN(CCC(O)C3CCCCC3)CC2C)c1.N>>CC1CN(CCC(O)C2CCCCC2)CCC1(C)c1cccc(C(N)=O)c1,,CO,,[C-]#N.[Na+],,test
US20150336938A1,CI.COc1cc2c(O)c3c(c(-c4ccc(C#N)cc4)c2cc1OC)C(=O)OC3>>COc1cc2c(OC)c3c(c(-c4ccc(C#N)cc4)c2cc1OC)C(=O)OC3,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US04786640,COC(=N)Cc1cccc2ccccc12.O=C(Cl)c1cccc2c(Br)cccc12>>COC(Cc1cccc2ccccc12)=NC(=O)c1cccc2c(Br)cccc12,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US20090156607A1,CCCC1CC(=O)N(CO)C1.c1ccc(-c2cc3ncccn3n2)cc1>>CCCC1CC(=O)N(Cc2c(-c3ccccc3)nn3cccnc23)C1,,O=C(O)C(F)(F)F,,,,test
US20030207885A1,CCCc1c(CCl)nc2ccc(Cl)cn12.Fc1cccc(-c2ncc[nH]2)c1>>CCCc1c(Cn2ccnc2-c2cccc(F)c2)nc2ccc(Cl)cn12,,CC(=O)N(C)C,CCOC(C)=O,CO,ClCCl,test
US20100075952A1,CCOC(=O)c1c(CCCNCCN(C)C)[nH]c(C(=O)OC(C)(C)C)c1C>>Cc1c(C(=O)OC(C)(C)C)[nH]c2c1C(=O)N(CCN(C)C)CCC2,,Cc1ccccc1,,C[Al](C)C,,test
US20050288290A1,Cc1c(C(=O)NCCN2CCOCC2)cn2ncnc(Oc3ccc(N)cc3F)c12.Cc1ccc(F)c(C(=O)Cl)c1>>Cc1ccc(F)c(C(=O)Nc2ccc(Oc3ncnn4cc(C(=O)NCCN5CCOCC5)c(C)c34)c(F)c2)c1.Cl,,C1CCOC1,,CCN(CC)CC,,test
US20120058988A1,CC(C)Oc1ccc(N)cc1.N#Cc1cc(-c2ccc(Cl)c(Cl)c2)ccc1F>>CC(C)Oc1ccc(Nc2ccc(-c3ccc(Cl)c(Cl)c3)cc2C#N)cc1,,CCOC(C)=O,CS(C)=O,CC(C)(C)[O-].[K+],,test
US20100113475A1,C1CCNC1.CCn1nc(CC(=O)O)cc1N.O=C(Oc1c(F)c(F)c(F)c(F)c1F)C(F)(F)F>>CCn1nc(CC(=O)N2CCCC2)cc1NC(=O)C(F)(F)F,,CN(C)C=O,,c1ccncc1,,test
US20130190332A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4cc(C#C[Si](C)(C)C)ccn4c3-c3ccccc3)cc2)CCC1>>C[Si](C)(C)C#Cc1ccn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2c1,,CO,ClCCl,C1COCCO1,Cl,test
US20120238759A1,C1CCOC1.CC(C)(C)C(=O)Cl.O=C(O)COc1ccc(CC2SC(=O)NC2=O)cc1>>CC(C)(C)C(=O)O.O=C(O)COc1ccc(CC2SC(=O)NC2=O)cc1,,C1CCOC1,,CCCCN(CCCC)CCCC,,test
US20100041714A1,CC(C)(C)OC(=O)COc1cccc2c1CCC[C@H]2NS(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(Cl)c1>>O=C(O)COc1cccc2c1CCC[C@H]2NS(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(Cl)c1,,C1CCOC1,,[Na+].[OH-],,test
US20090137588A1,COc1ccc(O)cc1.Nc1cccc(Nc2cc(Cl)ncn2)n1>>COc1ccc(Oc2cc(Nc3cccc(N)n3)ncn2)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20130059834A1,Cc1ccc(CNC=O)nc1>>Cc1ccc2cncn2c1,,Cc1ccccc1,,O=P(Cl)(Cl)Cl,,test
US05412104,CCCCCCn1c(=O)c(CBr)c(OC)c2cc(C)ccc21.c1c[nH]cn1>>CCCCCCn1c(=O)c(Cn2ccnc2)c(OC)c2cc(C)ccc21,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20040206940A1,CC12N3CCN1CCN1C(CO)CN(CC3)C12C>>CC12NCCN3CCN(CCN1)C32C,,CCO,,Cl,,test
US20130102611A1,CC(=O)O[C@@H]1CCNc2nc(-c3ccccc3)c(-c3ccccc3)nc21.CCOC(=O)CCCCCC=O>>CCOC(=O)CCCCCCN1CC[C@@H](OC(C)=O)c2nc(-c3ccccc3)c(-c3ccccc3)nc21,,ClCCCl,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150291554A1,CC(=O)Nc1c(C#N)c(-c2cccc(Cc3ccc(Cl)cc3)c2)nn1C1CCCN(C(=O)OCc2ccccc2)C1>>NC(=O)c1c(-c2cccc(Cc3ccc(Cl)cc3)c2)nn(C2CCCNC2)c1N,,CCO,,[Na+].[OH-],,test
US20100317693A1,CC(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)NC1Cc2cccc(NC(=O)CCCCl)c2NC1=O>>CC(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)NC1Cc2cccc(N3CCCC3=O)c2NC1=O,,CN(C)C=O,,[H-].[Na+],,test
US20040072847A1,Clc1ccc2nc(Cl)[nH]c2n1.O=C1OC2(CCNCC2)c2ccccc21>>O=C1OC2(CCN(c3nc4ccc(Cl)nc4[nH]3)CC2)c2ccccc21,,CN1CCCC1=O,,O,,test
US20130065861A1,CCOP(=O)(CCCOc1ccc(CCNC(=O)OC(C)(C)C)cc1)OCC>>CCOP(=O)(CCCOc1ccc(CCN)cc1)OCC,,ClCCl,,C1COCCO1,Cl,test
US20120328569A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3cc(C=O)cc(-c4nc5c(F)cccc5o4)c3)cc12.C[Mg]Br>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3cc(-c4nc5c(F)cccc5o4)cc(C(C)O)c3)cc12,,C1CCOC1,,,,test
US20080027049A1,CC(C)(C)[O-].O=C(CCl)Nc1ccc2oc3c(c2c1)CCCCC3>>CC(C)(C)OCC(=O)Nc1ccc2oc3c(c2c1)CCCCC3,,CN(C)C=O,,O,,test
US05219862,COC(=O)[C@@H]1C[C@@H]2c3cccc4[nH]c(C=O)c(c34)C[C@H]2N(C#N)C1>>COC(=O)[C@@H]1C[C@@H]2c3cccc4[nH]c(CO)c(c34)C[C@H]2N(C#N)C1,,CC#N,,[BH4-].[Na+],,test
US03948996,COC(CC(C)CCCC(C)(C)SC)OC>>CSC(C)(C)CCCC(C)CC=O,,C1CCOC1,,Cl,,test
US05866583,Cc1nnsc1C(=O)O.NCCc1ccccc1>>Cc1nnsc1C(=O)NCCc1ccccc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20030216444A1,COc1cc(C)c(C=O)c(OC)c1OC.Clc1cnc(Cl)c(Cl)c1>>COc1cc(C)c(C(O)c2c(Cl)cnc(Cl)c2Cl)c(OC)c1OC,,CCOCC,Cc1ccccc1,CC(C)NC(C)C,[Li]CCCC,test
US20140057909A1,CC(C)N(NC(=O)c1ccc(O)cc1)C(=O)/C=C/c1cn(C(=O)OC(C)(C)C)c2ccccc12.CI>>COc1ccc(C(=O)NN(C(=O)/C=C/c2cn(C(=O)OC(C)(C)C)c3ccccc23)C(C)C)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070219182A1,O=C(Cl)CCCCCl.O=C1CCCNc2ccccc21>>O=C1CCCN(C(=O)CCCCCl)c2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05202344,CCCCCN1C(=O)C(O)=C(C(=O)OCC)C1C.NO>>CCCCCN1C(=O)C(=NO)C(C(=O)OCC)C1C,,c1ccncc1,,Cl,,test
US20100197679A1,CC(C)(C)OC(=O)N[C@@H]1CC(=O)CC[C@@H]1O.Cn1cc([N+](=O)[O-])cc([N+](=O)[O-])c1=O>>CC(C)(C)OC(=O)N[C@H]1Cc2ncc([N+](=O)[O-])cc2C[C@H]1O,,CO,N,,,test
US04797149,CCOC(=O)CN.CCOC(=O)c1c(C(F)(F)F)nc(C(F)(F)Cl)c(C(=O)OC)c1Cl>>CCOC(=O)CNc1c(C(=O)OCC)c(C(F)(F)F)nc(C(F)(F)Cl)c1C(=O)OC,,CN(C)C=O,,CCN(CC)CC,Cl,test
US04056621,Cc1[nH]cnc1CSCCCl.N#C[S-]>>Cc1[nH]cnc1CSCCSC#N,,CCO,,Cl,,test
US20070298104A1,COC(=O)c1ncc2c(Oc3ccc(F)cc3)cccc2c1O.O=C1CCC(=O)N1Br>>COC(=O)c1nc(Br)c2c(Oc3ccc(F)cc3)cccc2c1O,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20130143906A1,COC(=O)c1ccc(F)c(C)c1F>>Cc1c(F)ccc(CO)c1F,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100331326A1,Brc1ccc2nccnc2c1.Cc1ccncc1N1CCNC1=O>>Cc1ccncc1N1CCN(c2ccc3nccnc3c2)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20110257198A1,CCCOc1ccc(C)nc1C(=O)O.Cc1cccn2cc(C[C@@H]3CCCCN3)nc12>>CCCOc1ccc(C)nc1C(=O)N1CCCC[C@H]1Cc1cn2cccc(C)c2n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US04513139,CC(C)C[C@@H](N[C@@H]1OC(=O)[C@H]2[C@H]3C=C[C@H](C3)[C@H]21)C(=O)OCc1ccccc1.Cl>>CC(C)C[C@@H](NCc1ccccc1)C(=O)O.Cl,,O,,,,test
US20140142083A1,CI.Cc1c(C(=O)O)cc(Br)cc1[N+](=O)[O-]>>COC(=O)c1cc(Br)cc([N+](=O)[O-])c1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20120309745A1,O=C(CNC(=O)c1nc2n(c(=O)c1OCc1ccccc1)CC1CCC2(NC(=O)OCc2ccccc2)CC1)Cc1ccc(F)cc1>>NC12CCC(CC1)Cn1c2nc(C(=O)NCC(=O)Cc2ccc(F)cc2)c(O)c1=O,[Pd],CO,,Cl,,test
US20070117793A1,C=C(C)c1cccc(C#N)c1>>CC(C)c1cccc(C#N)c1,,CCOC(C)=O,,,,test
US20070149577A1,COc1ccc(F)cc1-c1ccc([C@@H](C)N)cc1.Cc1nn(C)c(C)c1S(=O)(=O)Cl>>COc1ccc(F)cc1-c1ccc([C@@H](C)NS(=O)(=O)c2c(C)nn(C)c2C)cc1,,ClCCl,,CCN(CC)CC,,test
US20110257151A1,CC1(C)Cc2c(C(=O)O)ccc(Cl)c2NC1c1cccc(N2CCOCC2)c1.NS(=O)(=O)C1CC1>>CC1(C)Cc2c(C(=O)NS(=O)(=O)C3CC3)ccc(Cl)c2NC1c1cccc(N2CCOCC2)c1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,[H-].[Na+],test
US20150239895A1,CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.CN(C)C=O.COc1ncc(-c2ccc3c(c2)c(C(C)=O)cn3CC(=O)O)cn1.F[P-](F)(F)(F)(F)F.O=C(Nc1cccc(Cl)n1)[C@@H]1NC[C@@H](F)C1Cl>>COc1ncc(-c2ccc3c(c2)c(C(C)=O)cn3CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(-c3ccccc3Cl)c2F)cn1,,CN(C)C=O,O,Cl,,test
US05356886,CC(C)OP(=O)(/C=C/C(CO)Cn1cnc2c(N)ncnc21)OC(C)C>>Nc1ncnc2c1ncn2CC(/C=C/P(=O)(O)O)CO,,CN(C)C=O,,C[Si](C)(C)Br,,test
US04474777,C[C@@H]1N=C(c2ccccc2Cl)c2c(ccc(NC(=O)NCC3COC(C)(C)O3)c2Br)N(C)C1=O>>C[C@@H]1N=C(c2ccccc2Cl)c2c(ccc(NC(=O)NCC(O)CO)c2Br)N(C)C1=O,,CCO,,Cl,,test
US20040186133A1,N#Cc1c(N)nc2ccccc2c1Cl.NCc1ccccc1>>N#Cc1c(N)nc2ccccc2c1NCc1ccccc1,,O,,,,test
US20150087699A1,C[C@@H](OCc1ccccc1)c1oc2ccccc2c(=O)c1-c1cccc(F)c1>>C[C@@H](O)c1oc2ccccc2c(=O)c1-c1cccc(F)c1,,ClCCl,,BrB(Br)Br,,test
US20100029710A1,CCc1nc2c(C)cc(C(=O)CC(C)C)nc2n1[C@H]1CCc2cc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)ccc21>>CCc1nc2c(C)cc(C(=O)CC(C)C)nc2n1[C@H]1CCc2cc(-c3ccccc3-c3nnn[nH]3)ccc21,,CO,,,,test
US05134111,CCCc1cccc2cccc(OCOC)c12.CN(C)C=O>>CCCc1cccc2ccc(C=O)c(OCOC)c12,,CCOCC,O,CCCCCC,[Li]CCCC,test
US20140249104A1,COc1cnc(C(=O)Nc2ccc(F)c([C@]3(CF)C[C@@H](C(F)(F)F)OC(NC(=O)c4ccccc4)=N3)c2)cn1>>COc1cnc(C(=O)Nc2ccc(F)c([C@]3(CF)C[C@@H](C(F)(F)F)OC(N)=N3)c2)cn1,,CO,,C1CCC2=NCCCN2CC1,,test
US20090246200A1,CC(=O)O[C@H]1[C@H](O[C@@H]2[C@@H](COCc3ccccc3)O[C@H](OCCCCCN(Cc3ccccc3)C(=O)OCc3ccccc3)[C@H](N=[N+]=[N-])[C@H]2OCc2ccc3ccccc3c2)O[C@H](COCc2ccccc2)[C@H](OCc2ccccc2)[C@@H]1OCc1ccccc1>>CC(=O)O[C@H]1[C@H](O[C@@H]2[C@@H](COCc3ccccc3)O[C@H](OCCCCCN(Cc3ccccc3)C(=O)OCc3ccccc3)[C@H](N=[N+]=[N-])[C@H]2O)O[C@H](COCc2ccccc2)[C@H](OCc2ccccc2)[C@@H]1OCc1ccccc1,,ClCCl,O,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US05747517,CCCc1c(COc2ccc(C=O)cc2)ccc(C(C)=O)c1O.CN1C(=O)CSC1=S>>CCCc1c(COc2ccc(C=C3SC(=S)N(C)C3=O)cc2)ccc(C(C)=O)c1O,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20110306636A1,CCOc1cc(C(=O)OC)ccc1-c1ccccc1C>>CCOc1cc(C(=O)O)ccc1-c1ccccc1C,,C1CCOC1,O,[Li+].[OH-],,test
US20160031903A1,CI.Cc1ccc(S(=O)(=O)NCC2(C(=O)O)CCCC2)cc1>>Cc1ccc(S(=O)(=O)N(C)CC2(C(=O)O)CCCC2)cc1,,O,,[Na+].[OH-],,test
US20160002246A1,CC(C)(C)OC(=O)N1CC(O)C1.CCOC(=O)c1ccc(O)cc1>>CCOC(=O)c1ccc(OC2CNC2)cc1,,Cc1ccccc1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120178765A1,COC[C@H](C)Oc1cc(CO)cc(C(=O)OC)c1>>COC[C@H](C)Oc1cc(CO)cc(C(=O)O)c1,,C1CCOC1,,[Na+].[OH-],,test
US20110201604A1,CCn1c(Nc2nc3ccc(Cl)cc3s2)nc2cc(C(=O)O)ccc21.COCCN>>CCn1c(Nc2nc3ccc(Cl)cc3s2)nc2cc(C(=O)NCCOC)ccc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160009704A1,CCOC(=O)c1nnc(CCCCn2cc(C(=O)NCc3cccc(C(F)(F)F)c3)nn2)s1.COCCN>>COCCNC(=O)c1nnc(CCCCn2cc(C(=O)NCc3cccc(C(F)(F)F)c3)nn2)s1,,CO,,,,test
US20110263584A1,CC(C)(O)c1ncc(Br)cn1.C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O>>C[C@@H](c1ccc(-c2cnc(C(C)(C)O)nc2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O=C([O-])O.[Na+],,test
US06962933B1,BrBr.CC(C)(C)c1ccc(C(=O)Cc2ccncc2)cc1>>Br.CC(C)(C)c1ccc(C(=O)C(Br)c2ccncc2)cc1,,CC(=O)O,,O,,test
US20140057937A1,Cc1nc(C(F)(F)F)cn1[C@@H](C)C(=O)O.Clc1ccc(-n2ncc3c2CCCN3)cc1>>Cc1nc(C(F)(F)F)cn1[C@@H](C)C(=O)N1CCCc2c1cnn2-c1ccc(Cl)cc1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20090270374A1,CC(C)(C)OC(=O)NC[C@H]1C[C@@H](O[Si](C)(C)C(C)(C)C)CN(CCn2c(=O)ccc3ccc(F)cc32)C1.Cl>>Cl.NC[C@H]1C[C@@H](O)CN(CCn2c(=O)ccc3ccc(F)cc32)C1,,CO,ClCCl,C1COCCO1,,test
US20090048263A1,CC(=O)Nc1ccc(NC(=O)OCC(Cl)(Cl)Cl)cn1.c1ccc(-c2cccc(N3CCNCC3)c2)cc1>>CC(=O)Nc1ccc(NC(=O)N2CCN(c3cccc(-c4ccccc4)c3)CC2)cn1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20140179672A1,CC(N)(C#N)Cc1ccc(F)cc1>>CC(N)(CN)Cc1ccc(F)cc1,O=[Pt]=O,CCO,CCOCC,Cl,,test
US20060258714A1,C=CCBr.Cc1ccccc1-c1c(O)cccc1Cl>>C=CCOc1cccc(Cl)c1-c1ccccc1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04758580,CCOC(=O)C(C)(C)CCCCOc1ccc(OCCCCCBr)cc1.Oc1ccccn1>>CCOC(=O)C(C)(C)CCCCOc1ccc(OCCCCCOc2ccccn2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04493833,C=CCn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(NC(=O)C(=NOC)c3csc(NC=O)n3)[C@H]2SC1>>C=CCn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(NC(=O)C(=NOC)c3csc(N)n3)[C@H]2SC1,,CO,,Cl,,test
US20080021019A1,CC(C)(C)OC(=O)N1CCN(c2nc(Br)cnc2N)C[C@@H]1Cc1ccccc1.CI>>CNc1ncc(Br)nc1N1CCN(C(=O)OC(C)(C)C)[C@@H](Cc2ccccc2)C1,,C1COCCO1,,CCOC(C)=O,CC(C)(C)[O-].[K+],test
US05994354,C1CCNCC1.O=C1OC(CCCCl)CN1N=Cc1ccccc1>>O=C1OC(CCCN2CCCCC2)CN1N=Cc1ccccc1,,CN(C)C=O,,,,test
US04212865,Nc1cccc2c(-c3ccccc3)c([N+](=O)[O-])oc12.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1cccc2c(-c3ccccc3)c([N+](=O)[O-])oc12)C(F)(F)F,,ClCCl,,,,test
US20080306125A1,CCOC(=O)c1cc2ccc(Br)cc2s1>>OCc1cc2ccc(Br)cc2s1,,C1CCOC1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20140323468A1,BrCC1CCOCC1.NC(=O)N1CCCc2cc(-c3cncc(O)c3)cnc21>>NC(=O)N1CCCc2cc(-c3cncc(OCC4CCOCC4)c3)cnc21,,CC(=O)N(C)C,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20140371199A1,CC1CCN(c2ccc(N)cc2)CC1.N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)O)cc4)cn23)cc1>>CC1CCN(c2ccc(NC(=O)c3ccc(-c4ccc5ncc(-c6ccc(C#N)cc6)n5c4)cc3)cc2)CC1,,CN(C)C=O,O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120136008A1,Cc1ccc2[nH]c3c(c2c1)CN(C)CC3.O=C(CBr)c1ccccc1>>Cc1ccc2c(c1)c1c(n2CC(=O)c2ccccc2)CCN(C)C1,,CN1CCCC1=O,,[K+].[OH-],,test
US04393061,ClCCCN1CCOCC1.Oc1ccc(OCc2cccc(F)c2)cc1>>Fc1cccc(COc2ccc(OCCCN3CCOCC3)cc2)c1,,CCO,,[K+].[OH-],,test
US05547658,Cn1sc(Cl)cc1=O.Cn1sccc1=O.O=C(O)CC(O)(CC(=O)O)C(=O)O>>Oc1cc2cc[nH]c2cc1O,,OCC(O)CO,,O,,test
US20040059146A1,C=CCCCCCC.O=[PH](OC1CCCCC1)c1ccccc1>>CCCCCC/C=C/P(=O)(OC1CCCCC1)c1ccccc1,,Cc1ccccc1,,,,test
US20160229843A1,CCS(=O)(=O)Cl.C[Si](C)(C)CCOCn1c(-c2nc3ccc(-c4ccc5cn[nH]c5c4)cc3o2)nc2ccccc21>>CCS(=O)(=O)n1ncc2ccc(-c3ccc4nc(-c5nc6ccccc6[nH]5)oc4c3)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20130116285A1,CC1(C)OB(c2cc(C#N)ccc2Oc2ccc(Cl)cc2)OC1(C)C.COc1cccnc1Br>>COc1cccnc1-c1cc(C#N)ccc1Oc1ccc(Cl)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])O.[Na+],,test
US20120277325A1,CC1C(C)(C)C2=C(C(=O)CCC2)C1(C)C.CCOC=O>>CC1C(C)(C)C2=C(C(=O)C(C=O)CC2)C1(C)C,,COCCOC,,[H-].[Na+],,test
US20140171408A1,N#Cc1cc(F)c(C(=O)N(C(=O)c2c(F)cc(C#N)cc2Cl)c2ccnc(Cl)c2F)c(Cl)c1>>N#Cc1cc(F)c(C(=O)Nc2ccnc(Cl)c2F)c(Cl)c1,,C1COCCO1,CO,[Na+].[OH-],,test
US20110076292A1,COc1ccc(CNc2cc3c(cn2)-c2nc(-c4nc(C)nn4C(C)C)cn2CCO3)cc1OC>>Cc1nc(-c2cn3c(n2)-c2cnc(N)cc2OCC3)n(C(C)C)n1,,O=C(O)C(F)(F)F,,,,test
US20020111375A1,O=C1NC(=O)c2c1c1c3cc(F)c(F)cc3[nH]c1c1c2c2cc(F)c(F)cc2n1[C@@H]1O[C@H](CO)C[C@H](O)[C@H]1OCc1ccccc1>>O=C1NC(=O)c2c1c1c3cc(F)c(F)cc3[nH]c1c1c2c2cc(F)c(F)cc2n1[C@@H]1O[C@@H]2CO[C@@H](C2)[C@H]1OCc1ccccc1,,c1ccncc1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06087502,O=C1C=C(c2ccccc2)C(=O)C=C1c1ccccc1>>Oc1cc(-c2ccccc2)c(O)cc1-c1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110136789A1,CCOC(=O)Cl.COC(=O)CCNCc1cccs1>>CCOC(=O)N(CCC(=O)OC)Cc1cccs1,,O,,C1CCOC1,O=C([O-])O.[Na+],test
US20110256099A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)OC)cc(F)c3C)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)O)ccc3C)cc12,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20050288367A1,CCOC(=O)CBr.Oc1ccc(OCc2ccc(F)cc2)cc1>>CCOC(=O)COc1ccc(OCc2ccc(F)cc2)cc1,,CCC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060094843A1,BrCc1ccccc1.CCOC(=O)C1CCCC1=O>>CCOC(=O)C1(Cc2ccccc2)CCCC1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100075998A1,CCOC(=O)c1c(C(=O)OC(C)(C)C)n(C)c2c1ccc1[nH]ncc12>>CCOC(=O)c1c(C(=O)O)n(C)c2c1ccc1[nH]ncc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150175602A1,CC(C)N.Clc1nc2ccncc2nc1Cl>>CC(C)Nc1nc2ccncc2nc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04880808,Fc1ccc(C(=CCCCBr)c2ccc(F)cc2)cc1>>Fc1ccc(C(CCCCBr)c2ccc(F)cc2)cc1,[Pd],CO,,[H][H],,test
US20140045746A1,CCOC(=O)C1C2Cc3cc(O)ncc3C21.Cc1cc(OCCCS(C)(=O)=O)ncc1-c1ccc(F)c(CBr)c1>>CCOC(=O)C1C2Cc3cc(OCc4cc(-c5cnc(OCCCS(C)(=O)=O)cc5C)ccc4F)ncc3C21,,Cc1ccccc1,,,,test
US20080132539A1,CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1.CCCCCI>>CCCCCn1cc(C[C@H](NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2)c2ccccc21,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05332717,COc1cc(OC)nc(Oc2cccc3c2C(=O)OC3OC)n1>>COc1cc(OC)nc(Oc2cccc3c2C(=O)OC3O)n1,,C1CCOC1,,Cl,,test
US04690923,C1CNCCN1.O=S1CCN(c2nc(Cl)nc3c(NCc4ccco4)ncnc23)CC1>>O=S1CCN(c2nc(N3CCNCC3)nc3c(NCc4ccco4)ncnc23)CC1,,C1COCCO1,,,,test
US20150368247A1,C[C@@H]1CC[C@@H](Cn2cnc3nc(-c4noc(=O)[nH]4)nc(Cl)c32)CC1.FC1(F)CCCNC1>>C[C@@H]1CC[C@@H](Cn2cnc3nc(-c4noc(=O)[nH]4)nc(N4CCCC(F)(F)C4)c32)CC1,,CS(C)=O,,,,test
US20120114739A1,COC(=O)c1ccc(Oc2cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n3nccc3n2)cc1.O=C1CCC(=O)N1I>>COC(=O)c1ccc(Oc2cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n3ncc(I)c3n2)cc1,,CC#N,,,,test
US20100121052A1,Cn1cc(-c2cc(O)cc(Nc3ncc4cc(C#C[Si](C)(C)C)ccc4n3)c2)cn1.OCCN1CCCC1>>Cn1cc(-c2cc(Nc3ncc4cc(C#C[Si](C)(C)C)ccc4n3)cc(OCCN3CCCC3)c2)cn1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100035857A1,CC(=O)O[C@@H](CC[C@H]1C(=O)N(c2ccc(CCCO)cc2)[C@@H]1c1ccc(CCCO)cc1)c1ccc(F)cc1>>O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2ccc(CCCO)cc2)N1c1ccc(CCCO)cc1,,CCO,,,,test
US20100048639A1,O=C(O)c1cc(-c2ccccc2)c(C(F)(F)F)s1.[H]/N=C(\NO)c1ccc(Cn2ccc(C(=O)OCC)n2)c(Cl)c1>>CCOC(=O)c1ccn(Cc2ccc(-c3noc(-c4cc(-c5ccccc5)c(C(F)(F)F)s4)n3)cc2Cl)n1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US06939867B2,CC(C)(C)OC(=O)N(CCOc1ccc([N+](=O)[O-])cc1)CC(O[Si](C)(C)C(C)(C)C)c1ccc(Cl)nc1>>CC(C)(C)OC(=O)N(CCOc1ccc(N)cc1)CC(O[Si](C)(C)C(C)(C)C)c1cccnc1,[Pd],CO,,O=C[O-].[NH4+],,test
US20160229814A1,CCn1c(=O)[nH]c(=O)c2cc([N+](=O)[O-])ccc21.C[Si](C)(C)CCl>>CCn1c(=O)n(C[Si](C)(C)C)c(=O)c2cc([N+](=O)[O-])ccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070225318A1,BrBr.O=C(O)c1cc[nH]n1>>O=C(O)c1n[nH]cc1Br,,CC(=O)O,,CCOCC,O,test
US04570007,CC1(C)OCC(C(Cl)CO)O1>>CC1(C)OCC(C2CO2)O1,,CCOCC,,[K+].[OH-],,test
US20140179667A1,CC(C)I.Cc1c(Br)cc(O)cc1Br>>Cc1c(Br)cc(OC(C)C)cc1Br,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160024115A1,COC(=O)c1sccc1Nc1nc(Cl)ncc1[N+](=O)[O-]>>COC(=O)c1sccc1Nc1nc(Cl)ncc1N,[Fe],CC(=O)O,,,,test
US20110172202A1,CC(C)(C)C(=O)Cl.CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4O)no2)cc1C#N>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4OC(=O)C(C)(C)C)no2)cc1C#N,,ClCCl,,c1ccncc1,,test
US05633371,C1CCOC1.COc1cc(C=O)cc([N+](=O)[O-])c1OC.O=S(=O)(O)O>>COc1cc(C(O)c2cccs2)cc([N+](=O)[O-])c1OC,,C1CCOC1,,[Li]CCCC,,test
US20050032786A1,CCCS.CN(C)C=O.CS(=O)(=O)Oc1cccc(-c2nc(=O)c3ccccc3s2)n1>>CCCSCc1cccc(-c2nc(=O)c3ccccc3s2)n1,,CN(C)C=O,O,CCOC(C)=O,[H-].[Na+],test
US20020151503A1,O=C(CCC(CP(=O)(O)Cc1ccccc1)C(=O)OCc1ccccc1)OCc1ccccc1>>O=C(O)CCC(CP(=O)(O)Cc1ccccc1)C(=O)O,[Pd],O,,,,test
US20090137557A1,CCOC(=O)C(Cl)C(C)=O.COc1ccccc1C(=N)N>>COc1ccccc1-c1nc(=O)c(Cl)c(C)[nH]1,,C1COCCO1,CO,C[O-].[Na+],,test
US04342704,CC(=O)C1C(C=O)C1(C)C.CCOP(=O)(OCC)C(Cl)Cl>>CC(=O)C1C(C=C(Cl)Cl)C1(C)C,,C1CCOC1,CN(C)C=O,O,,test
US20040138462A1,CCOC(=O)c1cccc(S(=O)(=O)c2ccc(CCN(Cc3ccccc3)C[C@H](O)c3cccc(Cl)c3)cc2)c1>>CCOC(=O)c1cccc(S(=O)(=O)c2ccc(CCNC[C@H](O)c3cccc(Cl)c3)cc2)c1,[Pd],Clc1ccccc1,,CCN(CC)CC,CO,test
US20140199263A1,Nc1c(F)cccc1F.O=C(O)c1cncc(Br)c1>>NC(=O)c1ccncc1,,ClCCl,,O=S(Cl)Cl,,test
US05298577,C=C.C=CC(=O)OCC.C=COC(C)=O>>C=C.C=CC(=O)OCC.C=COC(C)=O,,CC(C)(C)O,,,,test
US07157487B2,COC(=O)CCOC[C@@H]1C[C@H](F)CN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1C[C@@H](F)C[C@H]1COCCC(=O)O,,C1CCOC1,,[Na+].[OH-],,test
US20100234378A1,C#CC(C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(-c2ccc(OC)cc2)cc1>>C#CC(C)NS(=O)(=O)c1ccc(-c2ccc(OC)cc2)cc1,,Cc1ccccc1,ClCCl,O=C(O)C(F)(F)F,,test
US20090258885A1,CC(C)(C)C(c1ccccc1)c1cc(OCc2ccc3cc(F)ccc3n2)ccc1C(N)=NO.N#CCC(=O)O>>CC(C)(C)C(c1ccccc1)c1cc(OCc2ccc3cc(F)ccc3n2)ccc1-c1noc(CC#N)n1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US06495604B1,CC(C)(C)OC(=O)COC(=O)C1=CCCCC1S(=O)(=O)Nc1ccc(F)cc1F>>O=C(O)COC(=O)C1=CCCCC1S(=O)(=O)Nc1ccc(F)cc1F,,CCOC(C)=O,,Cl,,test
US20060293299A1,CON(C)C(=O)C1CN(C(=O)OC(C)(C)C)C1.Fc1cc(F)cc([Mg]Br)c1>>CC(C)(C)OC(=O)N1CC(C(=O)c2cc(F)cc(F)c2)C1,,C1CCOC1,,CCOCC,,test
US20100016369A1,CCOC(=O)Cn1ncc2c1CCC[C@H]2N(C)S(=O)(=O)c1cnc(Cl)c(Br)c1.Oc1ccc(Cl)cc1>>CCOC(=O)Cn1ncc2c1CCC[C@H]2N(C)S(=O)(=O)c1cnc(Oc2ccc(Cl)cc2)c(Br)c1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20100152236A1,CC=Cc1c(F)ccc(C2OCCO2)c1Cl>>CCCc1c(F)ccc(C(OC)OC)c1Cl,[Pd],CO,,,,test
US20130029954A1,C=C(C)[C@@H]1CC[C@]2(CNCC(=O)N3CCC(C(=O)OCC)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(CNCC(=O)N3CCC(C(=O)O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1COCCO1,CO,O,[Na+].[OH-],test
US20150031715A1,CC(C)[Si](Cl)(C(C)C)C(C)C.Oc1cc(Cl)cc(Cl)c1>>CC(C)[Si](Oc1cc(Cl)cc(Cl)c1)(C(C)C)C(C)C,,O,,CN(C)C=O,c1c[nH]cn1,test
US05227375,C=CC[Si](C)(C)C.CC(=O)O[C@H]1CC[C@H]2[C@@H]3C=CC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C>>C=CC[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@H]3OC(C)=O)[C@@H]21,Cl[Ti](Cl)(Cl)Cl,CCOCC,ClCCl,,,test
US06399616B1,CCOC(=O)C1CCN(Cc2ccccc2)CC1.NCCc1cccs1>>O=C(NCCc1cccs1)C1CCN(Cc2ccccc2)CC1,,CCO,,[Na],,test
US04591597,C/C=C/C(=O)NCCc1ccc(S(=O)(=O)Cl)cc1.N=C1NCCN1C1CCCCC1>>C/C=C/C(=O)NCCc1ccc(S(=O)(=O)N2CCN(C3CCCCC3)C2=N)cc1,,CC(C)=O,O,Cl,[Na+].[OH-],test
US20110034511A1,O=C(Nc1ccc(F)c([N+](=O)[O-])c1)c1ccc(F)cc1Cl>>Nc1cc(NC(=O)c2ccc(F)cc2Cl)ccc1F,,CCO,,Cl,[Na+].[OH-],test
US20100105657A1,O=Cc1cc([N+](=O)[O-])ccc1F.OC[C@@H]1CCCN1>>O=[N+]([O-])c1ccc(F)c(CN2CCC[C@H]2CO)c1,,C1CCOC1,,CC(=O)O,[BH3-]C#N.[Na+],test
US20100280030A1,COC(=O)c1ccc2oc(=O)[nH]c2c1.O=[N+]([O-])c1ccc(CBr)cc1[N+](=O)[O-]>>COC(=O)c1ccc2oc(=O)n(Cc3ccc([N+](=O)[O-])c([N+](=O)[O-])c3)c2c1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20090131464A1,COc1cc(C(=O)N2CCC3(CC2)CC(=O)c2cc(C(C)(C)C(=O)OCc4ccccc4)ccc2O3)nc2c(OC)cccc12>>COc1cc(C(=O)N2CCC3(CC2)CC(=O)c2cc(C(C)(C)C(=O)O)ccc2O3)nc2c(OC)cccc12,[Pd],CO,,,,test
US20140274703A1,Nc1cc(-c2ccc(Cl)c(Cl)c2Cl)nc(C(=O)[O-])c1Cl>>Nc1cc(-c2ccc(Cl)c(Cl)c2Cl)nc(C(=O)O)c1Cl,,CO,,[Na+].[OH-],,test
US04563310,CCOC(=O)CBr.CCP(=O)(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]>>CCOC(=O)COP(=O)(CC)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-],,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140309208A1,CC1(C=O)COC1.Cc1ccco1>>Cc1ccc(C(O)C2(C)COC2)o1,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US20090298815A1,CS(=O)(=O)N1CCC(N)CC1.O=S(=O)(Nc1cccc(-c2nc(C3CCC3)sc2-c2ccnc(Cl)n2)c1F)c1cc(F)ccc1F>>CS(=O)(=O)N1CCC(Nc2nccc(-c3sc(C4CCC4)nc3-c3cccc(NS(=O)(=O)c4cc(F)ccc4F)c3F)n2)CC1,,C1CCOC1,,,,test
US20030092677A1,CC(C)(C)OC(=O)Nc1ccc(-c2ccc(OCc3ccccc3)nc2)cc1NC(=O)CC(=O)c1sccc1Cl>>O=C1CC(c2sccc2Cl)=Nc2ccc(-c3ccc(OCc4ccccc4)nc3)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040116694A1,CC(C)(CC(=O)C(=O)O)c1ccccc1.CO>>COC(=O)C(=O)CC(C)(C)c1ccccc1,,CN(C)C=O,O,O=S(Cl)Cl,,test
US08614219B2,O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.O=c1cc(-c2ccncn2)nc2n1CCCCC2>>O=C(Oc1ccc([N+](=O)[O-])cc1)C1CCCCn2c1nc(-c1ccncn1)cc2=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20110144110A1,CCOC(=O)CCC(=O)CCC(=O)c1ccc(OC)cc1.Cc1cc(C(=O)O)ccc1N>>CCOC(=O)CCc1ccc(-c2ccc(OC)cc2)n1-c1ccc(C(=O)O)cc1C,,C1COCCO1,CCOC(C)=O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20050113387A1,COc1ccc(-c2nc(N)c(C(=O)O)nc2-c2ccc(=O)n(C(C)C)c2)cc1>>COc1ccc(-c2nc(N)cnc2-c2ccc(=O)n(C(C)C)c2)cc1,,Clc1ccccc1Cl,,,,test
US20030114669A1,C=C1N(C)c2ccc(OC(F)(F)F)cc2C1(C)C.O=Nc1c(O)ccc2ccccc12>>CN1c2ccc(OC(F)(F)F)cc2C(C)(C)C12C=Nc1c(ccc3ccccc13)O2,,CCO,,,,test
US06355653B1,CCOC(=N)CS(=O)(=O)c1ccccc1.Cc1ccc(C(=O)NN)s1>>Cc1ccc(C(=O)NN=C(N)CS(=O)(=O)c2ccccc2)s1,,ClC(Cl)Cl,,,,test
US20130331397A1,CC(C)(C)OC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)CC1c1cccc(F)c1>>CC(C)(C)OC(=O)N1C[C@H](O)CC1c1cccc(F)c1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20130261140A1,COc1ccc(Cn2cnc3c2C(=O)N(Cc2nc(C)c4ccccc4n2)C2=NCCN23)cc1>>Cc1nc(CN2C(=O)c3[nH]cnc3N3CCN=C23)nc2ccccc12,,O=C(O)C(F)(F)F,,,,test
US20140179680A1,CCOC(=O)CN[C@H]1CCC[C@@H]1N>>O=C1CN[C@H]2CCC[C@@H]2N1,,CCO,,CCN(CC)CC,,test
US20090156596A1,CCCP(=O)(CO)CCC.Cc1ccc(S(=O)(=O)Cl)cc1>>CCCP(=O)(CCC)COS(=O)(=O)c1ccc(C)cc1,,CCOCC,,CCN(CC)CC,,test
US20130217699A1,COC(=O)CNC(=O)c1sc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2c1CCCC2>>O=C(O)CNC(=O)c1sc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2c1CCCC2,,CO,O,[Li]O,,test
US20160009718A1,CCOC(=O)C1=C(C)C(C(C)NC)N2N=CC=CC12.CS(=O)(=O)Cl>>CCOC(=O)c1c(C)c(C(C)N(C)S(C)(=O)=O)n2ncccc12,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20030065187A1,C=C(C)CO.COc1ccc(I)cc1>>C=C(C)COc1ccc(OC)cc1,[Cu]I,Cc1ccccc1,,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US20110190263A1,CCc1cnc(N2CCc3c(cccc3OC3CNC3)C2)nc1.CS(=O)(=O)c1ncc2c(n1)CCN(S(C)(=O)=O)C2>>CCc1cnc(N2CCc3c(cccc3OC3CN(c4ncc5c(n4)CCN(S(C)(=O)=O)C5)C3)C2)nc1,,CS(C)=O,,CCN(C(C)C)C(C)C,Cl,test
US04337201,CC(C)(C)C(=O)OCCl.O=C(O)[C@@H]1C[C@H](c2ccccc2)CN1C(=O)OCc1ccccc1>>CC(C)(C)C(=O)OCOC(=O)[C@@H]1C[C@H](c2ccccc2)CN1C(=O)OCc1ccccc1,,CCOC(C)=O,CN(C)C=O,[F-].[K+],,test
US04220647,CCOC(CN(C(=O)OCc1ccccc1)c1ccc(Cl)cc1)OCC.Cl.NCCc1ccc(O)c(O)c1>>Cl.O=C(OCc1ccccc1)N(CC1NCCc2cc(O)c(O)cc21)c1ccc(Cl)cc1,,O,,CCCCO,,test
US05264430,C=C(C)C.CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](N)[C@H]2SC1>>CC(=O)OCC1=C(C(=O)OC(C)(C)C)N2C(=O)[C@@H](N)[C@H]2SC1,,C1COCCO1,,O=S(=O)(O)O,,test
US20040038239A1,CCCCc1ccc(Cc2ncccc2O)cc1.CI>>CCCCc1ccc(Cc2ncccc2OC)cc1,,CC(C)=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120184553A1,CN1CCN(S(=O)(=O)c2ccc(OCc3ccccc3)c(C(=O)O)c2)CC1.Nc1cccnc1>>CN1CCN(S(=O)(=O)c2ccc(OCc3ccccc3)c(C(=O)Nc3cccnc3)c2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20020002158A1,CC(C)S(=O)(=O)Cl.CC(CN)c1ccc(-c2ccsc2)s1>>CC(CNS(=O)(=O)C(C)C)c1ccc(-c2ccsc2)s1,,ClCCl,,CCN(CC)CC,,test
US05866568,COc1nc(C)cnc1NC(=O)OCC(C)C.O=S(=O)(Cl)c1cccnc1Cl>>COc1nc(C)cnc1N(C(=O)OCC(C)C)S(=O)(=O)c1cccnc1Cl,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20070135479A1,COc1ccc2cnccc2c1Br.ClCCl.O=C(OO)c1cccc(Cl)c1>>COc1ccc2c[n+]([O-])ccc2c1Br.Cl,,ClCCl,,CO,,test
US05623081,COc1ccc(CS[C@H]2CO[C@@H](CO)[C@@H]2O)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc(CS[C@H]2CO[C@@H](COS(=O)(=O)c3ccc(C)cc3)[C@@H]2O)cc1,,c1ccncc1,,,,test
US04243672,N.O=CC(=O)O.c1c[nH]c(CC2CC2)c1>>NC(C(=O)O)c1ccc(CC2CC2)[nH]1,,CCOCC,,Cl,O,test
US20130281432A1,Cn1cc(-c2cccc(NCc3sc(C(C)(C)C)nc3C(=O)O)c2CO[Si](C)(C)C(C)(C)C)cc(Nc2ccncn2)c1=O>>Cn1cc(-c2cccc(N3Cc4nc(C(C)(C)C)sc4C3=O)c2CO)cc(Nc2ccncn2)c1=O,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060160782A1,CCN(CC)S(F)(F)F.COc1cc2c(cc1O)CC[C@H]1[C@@H]3CC[C@H](O)[C@@]3(C)CC[C@H]21>>COc1cc2c(cc1O)CC[C@H]1[C@@H]3CC[C@@H](F)[C@@]3(C)CC[C@H]21,,ClCCl,,,,test
US05527800,CC(=O)N1CCC(CCC(=O)Cl)CC1.c1ccc2c(c1)[nH]c1ccccc12>>CC(=O)N1CCC(CCC(=O)c2ccc3[nH]c4ccccc4c3c2)CC1,,C[N+](=O)[O-],,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20130053383A1,CC(C)n1ncc2c(C(=O)[O-])cc(Br)cc21>>CC(C)n1ncc2c(C(=O)O)cc(Br)cc21,,CO,,C1CCOC1,[Na+].[OH-],test
US20160157491A1,NNc1ccc(OC(F)(F)F)cc1.O=CC1=C(Br)CCc2cc(Br)ccc21>>FC(F)(F)Oc1ccc(-n2ncc3c2CCc2cc(Br)ccc2-3)cc1,,CC(=O)O,,,,test
US20070066606A1,C[Si](C)(C)Br.O=[N+]([O-])c1cc(CO)ccc1F>>O=[N+]([O-])c1cc(CBr)ccc1F,,ClCCl,,,,test
US04992589,Nc1ccc(N)cc1.O=[N+]([O-])c1ccc(Cl)c(S(=O)(=O)CCO)c1>>Nc1ccc(Nc2ccc([N+](=O)[O-])cc2S(=O)(=O)CCO)cc1,,CO,,,,test
US04028379,CSC(=C[N+](=O)[O-])S(C)=O.NCC(F)(F)F>>CSC(=C[N+](=O)[O-])NCC(F)(F)F,,CO,,,,test
US20090093417A1,COC(=O)[C@@H]1C[C@H](N=[N+]=[N-])CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1C[C@H](N)CN1C(=O)OC(C)(C)C,[Pd],CO,,,,test
US20140005164A1,CC(=O)N1CCN(C(=O)[C@@H]2CC[C@@H](CNc3nc(Br)ccc3[N+](=O)[O-])CC2)CC1>>CC(=O)N1CCN(C(=O)[C@@H]2CC[C@@H](CNc3nc(Br)ccc3N)CC2)CC1,[Ni],C1CCOC1,O,,,test
US20110311474A1,FC1(F)CCNCC1.O=C(n1ccnc1)n1ccnc1.c1cc2c(ncc3cnc([C@@H]4CCCNC4)n32)[nH]1>>O=C(N1CCC(F)(F)CC1)N1CCC[C@@H](c2ncc3cnc4[nH]ccc4n23)C1,,c1ccncc1,,Cl,Cl,test
US20100216746A1,N#Cc1cc(F)cc(Cl)c1.O=C(O)c1ccccc1C(=O)NCc1ccc(Cl)c(O)c1>>N#Cc1cc(Cl)cc(Oc2cc(CN3C(=O)c4ccccc4C3=O)ccc2Cl)c1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US05432164,CC(=O)OC[C@H]1O[C@@H](n2cnc3c(Cl)nc(N)nc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O.CSSC>>CSc1nc(Cl)c2ncn([C@@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]3OC(C)=O)c2n1,,CC#N,,CC(C)CCON=O,,test
US20130123289A1,Fc1cccnc1Cl.N#CC1CCC1>>N#CC1(c2ncccc2F)CCC1,,Cc1ccccc1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20080090818A1,ON=CNc1nc(Br)cnc1Br>>Brc1ncc(Br)n2ncnc12,,O,,O=C([O-])O.[Na+],,test
US05231198,O=C(Cl)CCl.O[C@@H]1CCCC[C@H]1c1ccccc1OCc1ccccc1>>O=C(CCl)O[C@@H]1CCCC[C@H]1c1ccccc1OCc1ccccc1,CN(C)c1ccncc1,CCCCCC,ClCCl,CCOC(C)=O,O=C([O-])O.[Na+],test
US04888353,BrCCBr.Cc1cc(Br)c(O)c(Br)c1>>Cc1cc(Br)c(OCCBr)c(Br)c1,,CCO,,[K+].[OH-],,test
US20060142333A1,O=[N+]([O-])c1ccc2cccnc2c1>>Nc1ccc2cccnc2c1,[Pd],CO,,,,test
US20150353553A1,COC(=O)CC[C@@H](Nc1nc(Cl)nc2nc(-c3cc(C(C)C)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1>>COC(=O)CC[C@@H](Nc1ncnc2nc(-c3cc(C(C)C)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1,[Pd],CCO,,CC(=O)[O-].[Na+],,test
US20130317110A1,CC(=O)Nc1ccc(Cl)c(C=O)c1F.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)/C=C/c1c(Cl)ccc(NC(C)=O)c1F,,Cc1ccccc1,,[Na+].[OH-],,test
US04558049,CN1CCC(=O)CC1.O=[N+]([O-])c1ccccc1Br>>CN1CCC(O)(c2ccccc2[N+](=O)[O-])CC1,,C1CCOC1,CCCCCC,Cl,,test
US20100137290A1,CCOC(=O)C[C@@H](O)CCl.O=C=Nc1ccc2c(c1)OCCO2>>CCOC(=O)C[C@@H]1CN(c2ccc3c(c2)OCCO3)C(=O)O1,,c1ccccc1,,,,test
US20060148858A1,CCCc1cn(C(=O)OC(C)(C)C)nc1O.CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO>>CCCc1c[nH]nc1OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1CCC,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20020058659A1,O=C(CCCc1ccc(Cl)cc1)NCC1CCc2c(ncn2C(c2ccccc2)(c2ccccc2)c2ccccc2)C1.O=C(CCCc1ccc(Cl)cc1)NCC1CCc2ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c2C1>>O=C(Cc1ccc(Cl)cc1)NCC1CCc2[nH]cnc2C1,,CC(=O)O,O,,,test
US20100105657A1,CC(C)N1CCOc2c(Cl)cccc2C1.O=[N+]([O-])O>>CC(C)N1CCOc2c(Cl)cc([N+](=O)[O-])cc2C1,,O=C(O)C(F)(F)F,,,,test
US20070254873A1,COC(=O)c1cc(Br)cc2c1N(C(=O)OC(C)(C)C)CC2>>COC(=O)c1cc(Br)cc2c1NCC2,,O=C(O)C(F)(F)F,,ClCCl,[Na+].[OH-],test
US04925847,CCc1nc2c([nH]1)c(=O)[nH]c(=O)n2CC(C)CC.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CCc1nc2c([nH]1)c(=S)[nH]c(=O)n2CC(C)CC,,c1ccncc1,,[Na+].[OH-],,test
US06201006B1,CC(=O)Cl.CCOC(=O)CN1CCC[C@@H]1C(=O)N1CCC[C@H]1CCc1cc2ccc(C(=N)N)cc2n1CC>>CCOC(=O)CN1CCC[C@@H]1C(=O)N1CCC[C@H]1CCc1cc2ccc(C=NNC(C)=O)cc2n1CC,,ClCCl,,CCN(CC)CC,O,test
US20120309735A1,CCCCS.Cc1cc(Nc2nccc(S(C)(=O)=O)n2)cc(-c2cnc(N3CCCNC(=O)C3)s2)c1>>CCCCSc1ccnc(Nc2cc(C)cc(-c3cnc(N4CCCNC(=O)C4)s3)c2)n1,,CCOC(C)=O,CN(C)C=O,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20090143385A1,CNC.Cc1onc(-c2ccccc2)c1COc1ccc(I)nn1>>Cc1onc(-c2ccccc2)c1COc1ccc(N(C)C)nn1,[Cu]Br,,,,,test
US20160046613A1,CC(C)OB1OC(C)(C)C(C)(C)O1.c1cnn(C2CCC2)c1>>CC1(C)OB(c2ccnn2C2CCC2)OC1(C)C,,C1CCOC1,,[Li]CCCC,,test
US03954748,COC(=O)c1cc(OC)c(OC)cc1[N+](=O)[O-]>>COC(=O)c1cc(OC)c(OC)cc1N,[Ni],C1CCOC1,,,,test
US05763359,CCn1nc(C(F)(F)F)cc1C.O=[N+]([O-])O>>CCn1nc(C(F)(F)F)c([N+](=O)[O-])c1C,,O=S(=O)(O)O,,,,test
US20060166964A1,CN(C)S(N)(=O)=O.O=C(O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(O)Cc1ccccc1-3>>CN(C)S(=O)(=O)NC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(O)Cc1ccccc1-3,CN(C)c1ccncc1,CN(C)C=O,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US04238389,CCCC1(CCC)CCC(=O)OC1=O.O=P([O-])([O-])[O-]>>CCCC(CCC)(CCC(=O)O)C(=O)O,,C1CCOC1,,,,test
US20070244131A1,COc1nc(Cl)cc(NCCc2ccc(Cl)cc2Cl)n1.O=C(O)C1CCCNC1>>COc1nc(NCCc2ccc(Cl)cc2Cl)cc(N2CCCC(C(=O)O)C2)n1,,CN1CCCC1=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US08053459B1,COC(=O)c1ccc(-c2nn(-c3ccccc3)c3[se]ccc23)o1>>OCc1ccc(-c2nn(-c3ccccc3)c3[se]ccc23)o1,,O,,CCCCCC,CCOC(C)=O,test
US20120040985A1,CC(C)(c1ccc(Cl)c(Cl)c1)c1cnc(CCl)n1-c1ccc(F)cc1.COC(=O)c1cc(F)c(O)c(Cl)c1>>COC(=O)c1cc(F)c(OCc2ncc(C(C)(C)c3ccc(Cl)c(Cl)c3)n2-c2ccc(F)cc2)c(Cl)c1,,CC#N,,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US20090253677A1,BrCc1ccccc1.COC(=O)C1CNCC(C(=O)OC)C1>>COC(=O)C1CC(C(=O)OC)CN(Cc2ccccc2)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04607053,CC(C)=O.CC(C)=O.CC(C)COC(=O)Cl.CCCCCCCCCCc1ccc(C(=O)N(C)O)cc1.CCN(CC)CC.O=C=O>>CCCCCCCC/C=C\c1ccc(C(=O)N(CCCC(=O)O)OCc2ccccc2)cc1,,CC(C)=O,,,,test
US20080090794A1,Fc1ccc(CBr)cc1.Oc1ccccn1>>O=c1ccccn1Cc1ccc(F)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04622401,C=C(C)C#N.Cc1cccc(NN)n1>>Cc1cccc(N2CC(C)C(N)=N2)n1,,CCO,,[Na],,test
US04801609,CC(=O)SCC(Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O>>C[C@H](NC(=O)C(CS)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O,[Zn],CO,,N,,test
US20150239854A1,CC1(C)C(=O)N(Br)C(=O)N1Br.Cc1ccc(-c2ccccc2-c2nnnn2Cc2ccccc2)cc1>>BrCc1ccc(-c2ccccc2-c2nnnn2Cc2ccccc2)cc1,,CCOC(C)=O,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20080249130A1,CCOC(=O)c1ccccc1C(=O)CBr.Nc1nccs1>>CCOC(=O)c1ccccc1-c1cn2ccsc2n1,,CCO,O,,,test
US20140228439A1,CCOC(=O)C(C)(CCCBr)c1ccccc1>>CC(CO)(CCCBr)c1ccccc1,,ClCCl,,CO,[BH4-].[Li+],test
US20080300266A1,CO.Fc1cnc(N2CC[C@H](NCc3ccc(Cl)cc3Cl)C2)nc1Cl>>COc1nc(N2CCC(NCc3ccc(Cl)cc3Cl)C2)ncc1F,,COCCOC,,C[O-].[Na+],,test
US20160009714A1,C=C(C)c1ccc2ccc(C(=O)Nc3cnccc3N3C[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](NC(=O)OC(C)(C)C)C3)nc2c1>>CC(C)c1ccc2ccc(C(=O)Nc3cnccc3N3C[C@H](C)[C@@H](O)[C@H](N)C3)nc2c1,[Pd],CO,,C1COCCO1,Cl,test
US20160137636A1,COc1cc(Br)c(C)cc1B1OC(C)(C)C(C)(C)O1.Clc1ncnc2cc(SCc3ccccc3)ccc12>>COc1cc(Br)c(C)cc1-c1ncnc2cc(SCc3ccccc3)ccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20150353559A1,CCOC(=O)CBr.Oc1ccccc1C1CCCO1>>CCOC(=O)COc1ccccc1C1CCCO1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06093732,O=[N+]([O-])c1ccc(COCCOCc2ccccc2)cc1>>Nc1ccc(COCCOCc2ccccc2)cc1,O=[Pt]=O,CCOC(C)=O,,,,test
US20130338137A1,CC1(C)C(=O)Nc2nc(-c3nc(Cc4ccccc4F)c4ncccn34)nc(N)c21.ICI>>CC1(C)C(=O)Nc2nc(-c3nc(Cc4ccccc4F)c4ncccn34)nc(I)c21,,CN1CCCC1=O,,CC(C)CCON=O,,test
US20150299188A1,CC(=O)Nc1cc2c(cc1Cl)C(=O)CC(c1ncccc1F)O2>>CC(=O)Nc1cc2c(cc1Cl)CCC(c1ncccc1F)O2,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20100056510A1,COC(=O)[C@@H]1CCNC(=O)CCSc2cc(nc(N)n2)-c2cc(c(C)cc2C)C(=O)N1>>Cc1cc(C)c2cc1C(=O)N[C@H](C(=O)O)CCNC(=O)CCSc1cc-2nc(N)n1,,CO,,O,[Na+].[OH-],test
US20070093510A1,FC(F)(F)c1nc(Cl)c2[nH]cnc2n1.NC1CC1>>FC(F)(F)c1nc(NC2CC2)c2[nH]cnc2n1,,CCO,,,,test
US20010031868A1,Nc1nc(Cl)c(N)c(Cl)n1.O=CO>>Nc1nc(Cl)c(NC=O)c(Cl)n1,,Cc1ccccc1,,O,,test
US06294668B1,O=C(C[n+]1ccc(CN2CC/C(=C\C3=C(C(=O)[O-])N4C(=O)[C@@H](NC(=O)CBr)[C@H]4SC3)C2=O)cc1)Nc1ccc(O)c(F)c1.Oc1ccc(S)cc1>>O=C(C[n+]1ccc(CN2CC/C(=C\C3=C(C(=O)[O-])N4C(=O)[C@@H](NC(=O)CSc5ccc(O)cc5)[C@H]4SC3)C2=O)cc1)Nc1ccc(O)c(F)c1,,CN(C)C=O,,CCN(CC)CC,,test
US20060041137A1,CCCC1=NNC(=O)/C1=C1/C=C(Sc2ccc(N)cc2)c2ccccc2N1.CN(C)CCCC(=O)Cl>>CCCC1=NNC(=O)/C1=C1/C=C(Sc2ccc(NC(=O)CCCN(C)C)cc2)c2ccccc2N1,,C1CCOC1,,,,test
US20140079632A1,O=C(Cl)C(=O)Cl.[N-]=[N+]=NCCCCCCCC(=O)O>>[N-]=[N+]=NCCCCCCCC(=O)Cl,CN(C)C=O,Cc1ccccc1,,,,test
US05173496,BrC(c1ccccc1)c1ccccc1.CCOC(=O)n1[nH]c(=O)c2ccccc21>>CCOC(=O)n1c2ccccc2c(=O)n1C(c1ccccc1)c1ccccc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20110021573A1,C[C@H]1[C@@H](c2ccccc2)OC(=O)N1Cc1cc(C(F)(F)F)ccc1B1OC(C)(C)C(C)(C)O1.O=C(O)Cc1cc(Br)ccc1F>>C[C@H]1[C@@H](c2ccccc2)OC(=O)N1Cc1cc(C(F)(F)F)ccc1-c1ccc(F)c(CC(=O)O)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US05183820,CC(C)Br.O=C1NCCc2[nH]c3c(F)cccc3c21>>CC(C)n1c2c(c3cccc(F)c31)C(=O)NCC2,,CN(C)C=O,,O,[H-].[Na+],test
US20120258949A1,O=C(/C=C/c1ccc2c(c1)C(=O)CC1(CCN(Cc3ccccc3)C1)O2)NOC1CCCCO1>>O=C(/C=C/c1ccc2c(c1)C(=O)CC1(CCN(Cc3ccccc3)C1)O2)NO,,ClCCl,,CCOCC,Cl,test
US20090137580A1,CC(O)(c1ccc(F)c(N)c1)C(F)(F)F.Cn1ccc2ncnc(Oc3ccc(N)c(Cl)c3)c21.O=C(Cl)Oc1ccccc1>>Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cc(C(C)(O)C(F)(F)F)ccc4F)c(Cl)c3)c21,,CN1CCCC1=O,,c1ccncc1,,test
US04431661,BrCCc1ccccc1.COc1cccc(C23CNCC2CC3=O)c1>>COc1cccc(C23CN(CCc4ccccc4)CC2CC3=O)c1,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US04263207,N.O=C(Cl)c1ccc2c(c1)Sc1ccccc1NC2=O>>NC(=O)c1ccc2c(c1)Sc1ccccc1NC2=O,,C1CCOC1,,,,test
US20080125409A1,CC(C)(C)O.CCOC(=O)C(NC(=O)c1ccc(C(=O)OCc2ccccc2)cn1)C(=O)OCC.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CCOC(=O)C(NC(=O)c1ccc(NC(=O)OC(C)(C)C)cn1)C(=O)OCC,,C1COCCO1,,CCN(CC)CC,,test
US20090208485A1,CC(C)(C)OC(=O)N1CCC(O)(c2cc(C(F)(F)F)ccn2)CC1>>CC(C)(C)OC(=O)N1CC=C(c2cc(C(F)(F)F)ccn2)CC1,,c1ccncc1,,O=S(Cl)Cl,,test
US20080319188A1,Cl.O=C(Nc1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)c(F)c2)ccn1)N1CCC1>>Cl.O=C(Nc1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)c(F)c2)ccn1)N1CCC1,,CC(C)=O,,,,test
US20130131040A1,N#Cc1ncc(N[C@@H]2CCCC[C@@H]2N)nc1Nc1cccc(-c2ncccn2)c1.OO>>NC(=O)c1ncc(N[C@@H]2CCCC[C@@H]2N)nc1Nc1cccc(-c2ncccn2)c1,,CCO,CS(C)=O,CC(=O)O,[Na+].[OH-],test
US05807806,COC(=O)c1ccc(S(C)(=O)=O)c(C(OC)OC)c1Cl>>COC(OC)c1c(S(C)(=O)=O)ccc(C(=O)O)c1Cl,,CO,,Cl,[Na+].[OH-],test
US05171860,CCOC(=O)C1=C(Br)C(OCC)=NS1=O.N>>CCOC(=O)C1=C(N)C(OCC)=NS1=O,,CC#N,,,,test
US03946009,Clc1nccnc1Cl.OCc1ccccc1>>Clc1nccnc1OCc1ccccc1,,c1ccccc1,,[H-].[Na+],,test
US20040224969A1,C=Cc1cccc(F)c1.CCOC(=O)C=O.Nc1cc(Cl)cc(Cl)c1>>O=C(O)C1CC(c2cccc(F)c2)c2c(Cl)cc(Cl)cc2N1,,CC#N,CCO,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20060079572A1,CCC(O)C(C)C1OC1CC(C)/C=C/C=C(\C)C1OC(=O)CC(O)CCC(C)(O)C(OC(C)=O)C=CC1C.Cc1ccc(S(=O)(=O)Cl)cc1>>CCC(OS(=O)(=O)c1ccc(C)cc1)C(C)C1OC1CC(C)/C=C/C=C(\C)C1OC(=O)CC(O)CCC(C)(O)C(OC(C)=O)C=CC1C,,CCOC(C)=O,ClCCl,CN(C)c1ccccn1,,test
US20010004669A1,CN1CCC(c2cccc3ccc(N)cc23)CC1.O=[N+]([O-])c1cccnc1Cl>>CN1CCC(c2cccc3ccc(Nc4ncccc4[N+](=O)[O-])cc23)CC1,CN(C)c1ccncc1,CN(C)C=O,,,,test
US20110243865A1,C1CCNCC1.Cc1ccc(CO)c(-c2ccccc2)c1-c1ccccc1>>Cc1ccc(CN2CCCCC2)c(-c2ccccc2)c1-c1ccccc1,,CC#N,ClC(Cl)Cl,O=S(Cl)Cl,,test
US20100317582A1,CCN.C[C@@H](NC1CC(C(=O)O)C1)c1cccc2ccccc12>>CCNC(=O)C1CC(N[C@H](C)c2cccc3ccccc23)C1,,CO,ClCCl,,,test
US04287085,CCCCc1ccc(O)cc1Br.CN1CCCC1=O>>CCCCc1ccc(O)cc1C#N,,Cl,O,,,test
US20030105151A1,COc1ccccc1-c1ccc2c(c1)NC(=O)C2.Cc1c(CCC(=O)O)c[nH]c1C=O>>COc1ccccc1-c1ccc2c(c1)NC(=O)C2=Cc1[nH]cc(CCC(=O)O)c1C,C1CCNCC1,CCO,,,,test
US20030176418A1,COc1ccc2c(c1)NC(=O)CO2.ClCCCI>>COc1ccc2c(c1)N(CCCCl)C(=O)CO2,,CCCCCCC,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100222318A1,CS(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)O)n2)cc1.Nc1cccc(O)c1N>>CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3nc4cccc(O)c4[nH]3)n2)cc1,,CCOC(C)=O,COCCOC,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20100076027A1,CCOC(=O)C(c1c2ccccc2nn1-c1ccc(Cl)cc1)C1CCCCC1>>O=C(O)C(c1c2ccccc2nn1-c1ccc(Cl)cc1)C1CCCCC1,,CO,,[Na+].[OH-],,test
US20120035143A1,CC(C)(O)C1(N)CC1.Clc1nc(Cl)c2c(n1)CCS2>>CC(C)(O)C1(Nc2nc(Cl)nc3c2SCC3)CC1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20100190826A1,CCOC(=O)c1cccc(-n2c(=O)[nH]c3cc(C(F)(F)F)ccc32)c1.O=P(Cl)(Cl)Cl>>CCOC(=O)c1cccc(-n2c(Cl)nc3cc(C(F)(F)F)ccc32)c1,,O=P(Cl)(Cl)Cl,,ClP(Cl)(Cl)(Cl)Cl,,test
US20040067939A1,CCI.O=C(c1c[nH]c2cc(Cl)ccc12)C(F)(F)F.[OH-]>>CCn1cc(C(=O)O)c2ccc(Cl)cc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030105139A1,O=[N+]([O-])c1cc[n+]([O-])c(Oc2cccnc2)c1>>Nc1ccnc(Oc2cccnc2)c1,[Fe],CC(=O)O,,,,test
US05185352,CCCCCCCCCCCCCCCCCCOc1coc(CO)cc1=O.CCCN>>CCCCCCCCCCCCCCCCCCOc1cn(CCC)c(CO)cc1=O,,CCO,O,,,test
US05175301,CSC(=C[N+](=O)[O-])N(C)C.Nc1ccc(Cl)nc1>>CN(C)C(=C[N+](=O)[O-])Nc1ccc(Cl)nc1,,CCO,ClC(Cl)Cl,,,test
US04220647,BrB(Br)Br.COc1cc2c(cc1OC)C(CN(c1ccccc1)c1ccccc1)NCC2>>Br.Oc1cc2c(cc1O)C(CN(c1ccccc1)c1ccccc1)NCC2,,ClCCl,,,,test
US20110105544A1,CC(=O)OCBr.COc1ccc(NS(=O)(=O)c2cccc(CCCC(CCc3ccccc3)C(=O)O)c2)cc1OC>>COc1ccc(NS(=O)(=O)c2cccc(CCCC(CCc3ccccc3)C(=O)OCOC(C)=O)c2)cc1OC,,CC#N,,CCN(C(C)C)C(C)C,,test
US20090318732A1,C=COCC.CC(=CCC(C=C(C)CCC=C(C)C(O)C(C1=C(C)CCCC1(C)C)S(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1)CCC=C(C)C(O)C(C1=C(C)CCCC1(C)C)S(=O)(=O)c1ccccc1.Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1>>CCOC(C)OC(C)OCC,,ClCCl,,,,test
US20120122888A1,CC(C)(C)c1c(N)nn2cccnc12.O=C(Cl)CCC1CCCC1>>CC(C)(C)c1c(NC(=O)CCC2CCCC2)nn2cccnc12,,c1ccncc1,,,,test
US20120134934A1,NC(C(=O)O[C@H]1CN2CCC1CC2)c1ccccc1.O=S(=O)(Cl)c1ccccc1>>O=C(O[C@H]1CN2CCC1CC2)C(NS(=O)(=O)c1ccccc1)c1ccccc1,,ClCCl,,,,test
US20100190764A1,C[Si](C)(C)N[Si](C)(C)C.O=C(O)C1CCCN(C2CCC3(Cc4ccccc4Cc4ccccc43)C2)C1>>NC(=O)C1CCCN(C2CCC3(Cc4ccccc4Cc4ccccc43)C2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20100093757A1,Cc1ccc(NC(=O)[C@@H](O)COCCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)nc1.Clc1ccccc1-n1nnc2c(Cl)ncnc21>>Cc1ccc(NC(=O)[C@H](COCCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)Oc2ncnc3c2nnn3-c2ccccc2Cl)nc1,,C1CCOC1,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20120214803A1,Nc1ccc(Cl)c2cccnc12.O=[N+]([O-])c1cc(C(F)(F)F)ccc1S(=O)(=O)Cl>>O=[N+]([O-])c1cc(C(F)(F)F)ccc1S(=O)(=O)Nc1ccc(Cl)c2cccnc12,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20140056849A1,CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(Cl)cc4)cc23)c1F.O=C(Cl)c1cccnc1>>CCCS(=O)(=O)N(C(=O)c1cccnc1)c1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(Cl)cc4)cc23)c1F,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20090312369A1,CC(C)(C)OC(=O)N[C@H](CO)C[C@H]1CCCOC1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC[C@H](C[C@H]2CCCOC2)NC(=O)OC(C)(C)C)cc1,,CCOC(C)=O,ClCCl,c1ccncc1,,test
US20130143859A1,Cc1cc(C2CCN(C(=O)[C@@H]3C[C@@](C)(N)C[C@H]3c3ccc(F)cc3F)CC2)n(-c2ccc(F)c(Cl)c2)n1.ICCOCCI.O=C(O)C(F)(F)F>>Cc1cc(C2CCN(C(=O)[C@@H]3C[C@@](C)(N4CCOCC4)C[C@H]3c3ccc(F)cc3F)CC2)n(-c2ccc(F)c(Cl)c2)n1.O=C(O)C(F)(F)F,,CC(=O)N(C)C,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050288338A1,C1CCC(NC2CC2)CC1.O=C(O)C1(c2ccc(Cl)cc2)CC1>>O=C(N(C1CCCCC1)C1CC1)C1(c2ccc(Cl)cc2)CC1,,CN(C)C=O,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US20070275962A1,CCO.NC(=O)c1c(NC(=O)C2CC2)sc2c1CCC(=O)C2>>CCOc1ccc2c(C(N)=O)c(NC(=O)C3CC3)sc2c1,,CCO,ClC(Cl)Cl,CC#N,O,test
US06335344B1,O=C(O)c1cc2c(cc1[N+](=O)[O-])OCO2>>Nc1cc2c(cc1C(=O)O)OCO2,[Pd],CCO,,,,test
US20130225552A1,Nc1cncnc1N[C@@H]1C[C@@H](Nc2ncc3ccccc3n2)C1.O=C(Cl)C1CC1>>c1ccc2nc(N[C@@H]3C[C@@H](n4c(C5CC5)nc5cncnc54)C3)ncc2c1,,C1CCOC1,,CCN(CC)CC,,test
US04315016,CC(=O)Cl.O=Cc1ccccc1.c1nc[nH]n1>>CCOCc1ccccc1-n1cncn1,[Cu],,,,,test
US04859701,CCCC=O.COC(=O)c1c2ccc(C(C)C)ccc-2oc1=O>>CCc1cc(C(=O)OC)c2ccc(C(C)C)ccc1-2,,CCO,,C1COCCN1,,test
US20150050325A1,CC(C)(C)OC(=O)NCC(=O)Nc1cncc(-c2nn3c(=O)cc(N4CCN(C(=O)OC(C)(C)C)CC4)nc3s2)c1>>NCC(=O)Nc1cncc(-c2nn3c(=O)cc(N4CCNCC4)nc3s2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100029697A1,CC(C)(C)c1nc(N)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2n1.CS(=O)(=O)O>>CC(C)(C)c1nc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c(=O)[nH]1,,CCOC(C)=O,,O,,test
US20070249649A1,CC(C)(CO[Si](C)(C)C(C)(C)C)c1ccc(N)c(Br)c1.CC1(C)CC=C(B(O)O)CC1>>CC1(C)CC=C(c2cc(C(C)(C)CO[Si](C)(C)C(C)(C)C)ccc2N)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US20110021520A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C1COCCC(c2ccccc2F)(C(F)(F)F)N1>>Fc1ccccc1C1(C(F)(F)F)CCOCC(=S)N1,,C1CCOC1,,,,test
US20130338134A1,CCN1C(=O)N(c2c(F)c(OC)cc(OC)c2F)Cc2cnc3c(cc(C=O)n3S(=O)(=O)c3ccccc3)c21>>CCN1C(=O)N(c2c(F)c(OC)cc(OC)c2F)Cc2cnc3c(cc(CO)n3S(=O)(=O)c3ccccc3)c21,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20140024694A1,O=Cc1ccc(F)cc1C(F)(F)F.OCCO>>Fc1ccc(C2OCCO2)c(C(F)(F)F)c1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040209917A1,Br[Mg]c1ccccc1.Cc1cc(C)c(Nc2nc(C)ccc2S(=O)(=O)c2ccc(C=O)cc2)c(C)c1>>Cc1cc(C)c(Nc2nc(C)ccc2S(=O)(=O)c2ccc(C(O)c3ccccc3)cc2)c(C)c1,,C1CCOC1,,,,test
US20100009986A1,CNC1(c2ccccc2)CCC2(CC1)OCCO2>>CNC1(c2ccccc2)CCC(=O)CC1,,O,,Cl,,test
US20070082912A1,CCOC(=O)c1ccnc(-n2c(C)ccc2-c2cc(Cl)ccc2O)c1.Fc1ccc(CBr)cc1>>CCOC(=O)c1ccnc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccc(F)cc2)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20060135619A1,O=C(O)c1cc(F)ccc1[N+](=O)[O-].Oc1ccccc1>>O=C(O)c1cc(Oc2ccccc2)ccc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120101127A1,Cc1cc(C#N)cc2c1NC(c1cccc(Br)c1)CC2(C)C.NC1(C(=O)O)CC1>>Cc1cc(C#N)cc2c1NC(c1cccc(NC3(C(=O)O)CC3)c1)CC2(C)C,[Cu]I,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120157476A1,O=C(O)CNC(=O)c1cnc(OCC(F)(F)F)c(-c2ccc(Cl)c(Cl)c2)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C1OC(c2cnc(OCC(F)(F)F)c(-c3ccc(Cl)c(Cl)c3)c2)=NC1C(=O)C(F)(F)F,,CC(C)=O,,,,test
US05998433,C=O.CNC.O=C(CCCCCc1ccccc1)N1CCc2ccoc2C1>>CN(C)Cc1cc2c(o1)CN(C(=O)CCCCCc1ccccc1)CC2,,CC(=O)O,,,,test
US20090156612A1,CCOC(=O)Cl.CCOC(=O)c1ncn(C2CCCCC2(O)CN)c1-c1ccccc1>>CCOC(=O)NCC1(O)CCCCC1n1cnc(C(=O)OCC)c1-c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20150057271A1,COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc3c(c2)OCC(=O)N3)cc1>>COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc3c(c2)OCCN3)cc1,,C1CCOC1,C1CCOC1,,,test
US20040077605A1,CI.Cc1ccc(CCNC(=O)c2ccc(F)cc2)o1>>Cc1ccc(CCN(C)C(=O)c2ccc(F)cc2)o1,,C1CCOC1,,[H-].[Na+],,test
US20120277224A1,CO.COc1cc(Cl)ccc1C(=O)C1C(=O)OC(C)(C)OC1=O>>COC(=O)CC(=O)c1ccc(Cl)cc1OC,,CO,,,,test
US20120088755A1,CI.Cc1cc(Br)cc([N+](=O)[O-])c1N>>CNc1c(C)cc(Br)cc1[N+](=O)[O-],,CN(C)C=O,,O,[H-].[Na+],test
US04564630,CCC(O)(c1ccc(O)cc1)c1ccc(Cl)cc1.CCCCN=C=O>>CCCCNC(=O)Oc1ccc(C(O)(CC)c2ccc(Cl)cc2)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20150336986A1,C=C(COS(C)(=O)=O)C(c1nc(Cl)cs1)c1[nH]c(-c2cccc(F)c2)c2c(=O)n(C)c(=O)n(C)c12>>C=C1Cn2c(-c3cccc(F)c3)c3c(=O)n(C)c(=O)n(C)c3c2C1c1nc(Cl)cs1,,C1CCOC1,,[H-].[Na+],,test
US20020042421A1,O=CN1C2CCC1CC(N1CCNCC1)C2>>O=CN1C2CCC1CC(N1CCNCC1)C2,,ClCCl,,Cl,,test
US20120157448A1,CC12CC(=O)CCC1Oc1ccc(Br)cc1C21COC(N)=N1>>CC12CC(O)CCC1Oc1ccc(Br)cc1C21COC(N)=N1,,C1CCOC1,,CO,[BH4-].[Na+],test
US20070032478A1,Cc1cc(C(=O)Nc2cccc(C(=O)c3ccc4c(c3)NC(=O)C4=CO)c2)n(C)n1.Nc1ccc(OCCCN2CCC(F)C2)cc1>>Cc1cc(C(=O)Nc2cccc(C(=O)c3ccc4c(c3)NC(=O)C4=CNc3ccc(OCCCN4CCC(F)C4)cc3)c2)n(C)n1,,C1CCOC1,,,,test
US20070106095A1,CCOC(=O)c1cc2cc(C(CC)(CC)c3ccc(OCC(=O)C(C)(C)C)c(C)c3)cc(C)c2o1.OCCO>>CCOC(=O)c1cc2cc(C(CC)(CC)c3ccc(OCC4(C(C)(C)C)OCCO4)c(C)c3)cc(C)c2o1,,OCCO,,CCOCC,FB(F)F,test
US20100216836A1,COc1cccc(OC)c1OC[C@H](O)CO.CS(=O)(=O)Cl.ClCCl.O=S(=O)([O-])O>>COc1cccc(OC)c1OC[C@@H](COS(C)(=O)=O)OS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20140200216A1,CC(C)(C)OC(=O)N[C@H]1C[C@@H](C(F)(F)F)CN(c2ccncc2N)C1.O=C(Nc1cc2ccc(Br)cc2nc1C(=O)O)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@H]1C[C@@H](C(F)(F)F)CN(c2ccncc2NC(=O)c2nc3cc(Br)ccc3cc2NC(=O)OCc2ccccc2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070293497A1,COCCN(C[C@@H]1C[C@H]1C)c1cc(-c2nnc([C@@](C)(Cc3ccccc3)NC(=O)OC(C)(C)C)o2)c(Cl)c(N(Cc2ccccn2)S(C)(=O)=O)n1>>COCCN(C[C@@H]1C[C@H]1C)c1cc(-c2nnc([C@](C)(N)Cc3ccccc3)o2)c(Cl)c(N(Cc2ccccn2)S(C)(=O)=O)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100125058A1,CCc1c(CC(=O)OC)cc2ccc(F)cc2c1OC(C)=O>>CCc1c(CC(=O)OC)cc2ccc(F)cc2c1O,,CO,,Cl,C[O-].[Na+],test
US20070232607A1,CNC.COC(=O)[C@@H](C)Oc1cccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(Cl)c3)c12>>Cc1ccc(Oc2ccc(Nc3ncnc4cccc(O[C@H](C)C(=O)N(C)C)c34)cc2Cl)cn1,,CO,,,,test
US04661512,CC(=O)Cl.O=C1CC[C@@H](C(=O)OCc2ccccc2)N1>>CC(=O)N1C(=O)CC[C@H]1C(=O)OCc1ccccc1,,c1ccccc1,,[H-].[Na+],,test
US04962103,CC(=O)S[C@H]1C[C@@H](CO[Si](C)(C)C(C)(C)C)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1>>CC(=O)S[C@H]1C[C@@H](CO)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1,,CCOC(C)=O,CO,Cl,,test
US20110301148A1,CNc1ccccn1.O=S(=O)(Cl)c1ccc(Cl)nc1>>CN(c1ccccn1)S(=O)(=O)c1ccc(Cl)nc1,,ClCCl,,CCN(CC)CC,,test
US20070191333A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C1CCNC1>>CCOC(=O)C1CCN(C(=O)OC(C)(C)C)C1,,ClCCl,,,,test
US20120165324A1,O=C(CCl)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1.OCc1ccccc1>>O=C(COCc1ccccc1)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1,,C1CCOC1,,[H-].[Na+],,test
US20040102450A1,CC(C)(C)OC(=O)N1CCN(CCN)C(=O)C1.CN1CCOCC1.O=[N+]([O-])c1c(Cl)c(Cl)nc(Cl)c1Cl>>O=C1CNCCN1CCNc1ccncc1,,ClCCl,,,,test
US05438052,Cc1cc(Cl)n2nc(CN=[N+]=[N-])nc2n1.NC(N)=S>>Cc1cc(S)n2nc(CN=[N+]=[N-])nc2n1,,CCO,,,,test
US06165944,CC1CC(c2c(S(C)(=O)=O)ccc(C(=O)Cl)c2Cl)=NO1.Cn1nccc1O>>CC1CC(c2c(S(C)(=O)=O)ccc(C(=O)c3cnn(C)c3O)c2Cl)=NO1,,C1COCCO1,,CCN(CC)CC,O=C([O-])[O-].[K+].[K+],test
US20130005710A1,CC(C)=O.Cc1ccc(N2CCN(c3ccc(Br)nc3-c3ccc(C(C)C)cc3)CC2)cc1>>Cc1ccc(N2CCN(c3ccc(C(C)(C)O)nc3-c3ccc(C(C)C)cc3)CC2)cc1,,C1CCOC1,O,CCCCCC,[Li]CCCC,test
US05225207,CC(=O)OC(C)=O.N#CC1(N)CCC2CCC1C2>>CC(=O)NC1(C#N)CCC2CCC1C2,,CC(=O)OC(C)=O,,CCOCC,,test
US20110306591A1,CC1(C)OB(C2=CCOCC2)OC1(C)C.COc1ccc(CN(Cc2ccc(OC)cc2)[C@@H]2CC[C@@H](Oc3nccnc3Cl)CC2)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)[C@@H]2CC[C@@H](Oc3nccnc3C3=CCOCC3)CC2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20080200471A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1cc2cn[nH]c2cc1N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(c2ccc3cn[nH]c3c2)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20150299192A1,CC(=O)OC(C)=O.Cn1c(-c2nc(N)ncc2C#C[Si](C)(C)C)cc2c1CCN(C(=O)OC(C)(C)C)C2=O>>C#Cc1cnc(NC(C)=O)nc1-c1cc2c(n1C)CCN(C(=O)OC(C)(C)C)C2=O,,O,,,,test
US20020045747A1,CC(C)CO.CSCC[C@H](NC(=O)Cc1ccccc1)C(=O)O>>CSCC[C@H](NC(=O)Cc1ccccc1)C(=O)OCC(C)C,CN(C)c1ccncc1,C1COCCO1,,ClCCCl,,test
US20100184815A1,CC(C)(C)OC(=O)C(C)(C)Sc1ccc(C(=O)OCc2cn(Cc3ccccc3)nn2)cc1>>CC(C)(Sc1ccc(C(=O)OCc2cn(Cc3ccccc3)nn2)cc1)C(=O)O,,C1COCCO1,,Cl,,test
US20080207654A1,CCCCC(=O)C(Cc1ccc(-c2ccccc2C#N)cc1)C(=O)OCC.COCC(=N)N>>CCCCc1nc(COC)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1,,C1COCCO1,CO,Cl,C[O-].[Na+],test
US20060122394A1,CCOC(=O)c1cnc(N2CCN[C@H](C)C2)c(Cl)c1.Clc1cc(Cl)ncn1>>CCOC(=O)c1cnc(N2CCN(c3cc(Cl)ncn3)[C@H](C)C2)c(Cl)c1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20090137595A1,Cc1cc(C(=O)Nc2cccc([N+](=O)[O-])c2)n(C)n1>>Cc1cc(C(=O)Nc2cccc(N)c2)n(C)n1,[Pd],CCO,,NN,O,test
US06251921B1,COc1cc(C(=O)c2c(-c3ccc(OCCN4CCCC4)cc3)sc3cc(OCc4ccccc4)ccc23)ccc1CN1CCCC1>>COc1cc(C(=O)c2c(-c3ccc(OCCN4CCCC4)cc3)sc3cc(O)ccc23)ccc1CN1CCCC1,[Pd],C1CCOC1,,O=C[O-].[NH4+],,test
US04996218,BrCCCCCCBr.OCCCc1ccc2ccccc2n1>>BrCCCCCCOCCCc1ccc2ccccc2n1,,CCOCC,O,[Na+].[OH-],,test
US20050250781A1,BrCc1ccccc1.c1cc(-c2cc[nH]n2)ccn1>>C1=C(c2cc[nH]n2)CCN(Cc2ccccc2)C1,,CC(C)O,,,,test
US05753665,CC(=O)C(C)Cl.O=C(O)c1ccccc1>>CC(=O)C(C)OC(=O)c1ccccc1,,CC#N,,CCN(CC)CC,,test
US20050234265A1,CNC.COc1cc(C(C)(C)C)ccc1CC(=O)Cl>>COc1cc(C(C)(C)C)ccc1CC(=O)N(C)C,,C1CCOC1,ClCCl,,,test
US20120149691A1,N#Cc1cnn2cc([N+](=O)[O-])cc2c1Cl.Nc1ccccc1>>N#Cc1cnn2cc([N+](=O)[O-])cc2c1Nc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20130157996A1,CC(C)(C)[S@](=O)N[C@@H](c1ccc(C=O)cc1)c1ncccc1C(F)(F)F.C[Mg]Br>>CC(O)c1ccc([C@H](N[S@@](=O)C(C)(C)C)c2ncccc2C(F)(F)F)cc1,,C1CCOC1,,,,test
US04018922,CCCBr.c1ccc(CN2CCC3(CC2)OCCO3)cc1>>CCCC1(OCCO)CCN(Cc2ccccc2)CC1,,CCOCC,c1ccccc1,[Mg],,test
US20090197863A1,COC(=O)c1cccc(NC(=O)c2ccc(-c3ccccn3)cc2)c1O>>COC(=O)c1cccc2nc(-c3ccc(-c4ccccn4)cc3)oc12,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20090324581A1,CC(C)(C)OC(=O)CCN(CC(=O)N1CCc2cc(O)ccc21)C(=O)OC(C)(C)C.CC(C)Cc1ccc(CCl)cc1C(F)(F)F>>CC(C)Cc1ccc(COc2ccc3c(c2)CCN3C(=O)CN(CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc1C(F)(F)F,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090149548A1,CI.COC(=O)c1cc(OC)c(C(C)C)c(OC)c1>>COc1cc(C(C)O)cc(OC)c1C(C)C,,CCOCC,O,Cl,[BH4-].[Li+],test
US20090197959A1,CCOC(=O)c1ccc(Br)c(CN(CC)C(=O)OCc2ccccc2)c1>>CCN(Cc1cc(C(=O)O)ccc1Br)C(=O)OCc1ccccc1,,CO,,[Li+].[OH-],,test
US20120208827A1,N#Cc1ccc(N)c(NC[C@@H]2CCN(C(=O)C3CC3)C2)c1.O=Cc1ccc(Br)cc1>>N#Cc1ccc2nc(-c3ccc(Br)cc3)n(C[C@@H]3CCN(C(=O)C4CC4)C3)c2c1,,CCCCO,,CO,ClCCl,test
US20040014962A1,CC(C)(C)[Si](OC1CN(c2nc(C(=O)N3CCCCC3)cs2)C1)(c1ccccc1)c1ccccc1>>O=C(c1csc(N2CC(O)C2)n1)N1CCCCC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090105211A1,CN(C)CC(=O)O.Cc1ccc(N)cc1NC(=O)c1ccc(Nc2nc(-c3ccccc3)c3ccccc3n2)cc1>>Cc1ccc(NC(=O)CN(C)C)cc1NC(=O)c1ccc(Nc2nc(-c3ccccc3)c3ccccc3n2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110028481A1,BrCc1ccccc1.O=C(O)CN1CCOC1=O>>O=C(CN1CCOC1=O)OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100048591A1,COc1ncc(I)c(OC)n1>>COc1ncc(I)c(=O)[nH]1,,CO,,[Na+].[OH-],,test
US20120059030A1,CCOC(=O)C1CCCn2c(-c3ccc(-c4cnc(C)o4)c(OC)c3)nnc21.CI>>CCOC(=O)C1(C)CCCn2c(-c3ccc(-c4cnc(C)o4)c(OC)c3)nnc21,,CN(C)C=O,,O,[H-].[Na+],test
US20100130495A1,CC(C)(C)OC(=O)N1CCc2c(O)nc(Nc3ccc(-c4cnco4)cc3)nc2C1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCc2c(nc(Nc3ccc(-c4cnco4)cc3)nc2OS(=O)(=O)C(F)(F)F)C1,CN(C)c1ccncc1,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20060223801A1,CC(C)(C)OC(=O)NC1CCN(C(N)=S)CC1.CCOC(=O)C(Cl)C(=O)COCCOC>>CCOC(=O)c1sc(N2CCC(N)CC2)nc1COCCOC.Cl,,CCO,,,,test
US20070135461A1,C[Si](C)(C)CCOCn1ccc2c(-c3cn[nH]c3)ncnc21.O=C1C=CCCC1>>C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C4CCCC(=O)C4)c3)ncnc21,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20020035136A1,NCc1ccccc1.O=Cc1ccc(-c2cccc3ccccc23)c(Cl)c1Cl>>Clc1c(CNCc2ccccc2)ccc(-c2cccc3ccccc23)c1Cl,,ClCCCl,,CC(=O)O,O=C([O-])O.[Na+],test
US20060258714A1,Cc1ccc(S(=O)(=O)OC[C@H]2C=Cc3cccc(-c4c(Cl)cccc4Cl)c3O2)cc1>>Cc1ccc(S(=O)(=O)OC[C@H]2CCc3cccc(-c4c(Cl)cccc4Cl)c3O2)cc1,O=[Pt]=O,CCO,CCOC(C)=O,[H][H],,test
US20090221555A1,C#CCN1CCc2ccc([N+](=O)[O-])cc2CC1>>C#CCN1CCc2ccc(N)cc2CC1,,CCO,CCOC(C)=O,Cl[Sn]Cl,,test
US20120252815A1,CC(=O)OCCCCCCl.CC1(C)CCC(C)(C)c2cc(-c3csc(C4CCCNC4)n3)ccc21>>CC1(C)CCC(C)(C)c2cc(-c3csc(C4CCCN(CCCCCO)C4)n3)ccc21,,CO,,Br,[Na+].[OH-],test
US20050026925A1,C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3cc(F)c(C=O)nc3N21>>C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3cc(F)c(CO)nc3N21,,C1CCOC1,,[BH4-].[Li+],,test
US06518273B1,CCC(=O)Cl.Cn1c(-c2ccc(Cl)cc2)cc2cc(Cl)ccc21.O=C1CN(C(=O)OCc2ccccc2)CCN1>>Cn1c(-c2ccc(Cl)cc2)c(CCC(=O)N2CCN(C(=O)OCc3ccccc3)CC2=O)c2cc(Cl)ccc21,,CN(C)C=O,,O,[H-].[Na+],test
US20100087506A1,CC[C@]1(O)CCN(C(=O)OCc2ccccc2)[C@H]1C(C)C>>CC[C@]1(O)CCN[C@H]1C(C)C,[Pd],O,,,,test
US20110135668A1,Cc1cc(Nc2nc(Nc3ccccc3S(=O)(=O)C(C)C)c3c(C)n[nH]c3n2)c(OC(C)C)cc1C1CCNCC1.O=C(Cl)CBr>>Cc1cc(Nc2nc(Nc3ccccc3S(=O)(=O)C(C)C)c3c(C)n[nH]c3n2)c(OC(C)C)cc1C1CCN(C(=O)CBr)CC1,,ClCCl,,,,test
US20040097578A1,CCOC(=O)OCC.O=C1CCCN1c1ccc(OCc2cccc(F)c2)cc1>>CCOC(=O)C1CCN(c2ccc(OCc3cccc(F)c3)cc2)C1=O,,C1CCOC1,,[H-].[Na+],,test
US20020013333A1,C=C(C)C.CC(=O)SCC(C(=O)O)C1CCN(C(=O)OCc2ccccc2)CC1>>CC(=O)SCC(C(=O)OC(C)(C)C)C1CCN(C(=O)OCc2ccccc2)CC1,,ClCCl,,O=S(=O)(O)O,,test
US20100160322A1,COc1cccc2[nH]nc(C)c12>>Cc1n[nH]c2cccc(O)c12,,ClCCl,,BrB(Br)Br,,test
US05576324,C=O.CNC.Cc1ccc(O)c2ccc(=O)[nH]c12>>Cc1cc(CN(C)C)c(O)c2ccc(=O)[nH]c12,,CN(C)C=O,,,,test
US06077832,CC(=O)OC[C@@H]1O[C@H](n2c(Br)nc3cc(Cl)c(Cl)cc32)[C@@H](OC(C)=O)[C@H]1OC(C)=O.CC(C)CN>>CC(C)CNc1nc2cc(Cl)c(Cl)cc2n1[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O,,CN(C)C=O,,CCO,,test
US20090099173A1,C[C@H]1CN(c2nnc(Cl)c3ccncc23)CCN1.O=C(Cl)N1CCCCC1>>C[C@H]1CN(c2nnc(Cl)c3ccncc23)CCN1C(=O)N1CCCCC1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20020013354A1,CCOC(=O)COc1cccnc1C(=O)c1ccc(F)cc1>>O=C(O)c1oc2cccnc2c1-c1ccc(F)cc1,,Cc1ccccc1,,C,C[O-].[Na+],test
US04902835,COC(F)(F)C(F)=CCBr.O=S(=O)(O)O>>COC(=O)/C(F)=C/CBr,,CCCCC,,,,test
US20050101573A1,C[C@H](CCC(=O)O)[C@H]1CC=C2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](O[Si](C)(C)C(C)(C)C)C(C)(C)[C@@H]1CC3.N>>C[C@H](CCCN)[C@H]1CC=C2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](O[Si](C)(C)C(C)(C)C)C(C)(C)[C@@H]1CC3,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20030199550A1,C1CCNCC1.CN(C[C@@H]1CC[C@@H](COCCCCBr)CC1)S(=O)(=O)c1ccc(C(F)(F)F)cc1>>CN(C[C@@H]1CC[C@@H](COCCCCN2CCCCC2)CC1)S(=O)(=O)c1ccc(C(F)(F)F)cc1,,CC(=O)N(C)C,,,,test
US05744627,CCOC(=O)c1ccc(CN)cc1O.O=C(CCl)OC(=O)CCl>>CCOC(=O)c1ccc(CNC(=O)CCl)cc1O,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,Cl,test
US04689349,CCOC(=O)CCCC(CC)OCC>>CCOC(CC)CCCCO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070232627A1,COC(=O)C(C)(N)c1ccccc1>>CC(N)(CO)c1ccccc1,,CCO,,[BH4-].[Na+],,test
US20020120139A1,O=c1[nH]c(N[N+](=O)[O-])ncc1Cc1cccnc1.OCCCCCCCCc1ccccc1>>O=c1[nH]c(OCCCCCCCCc2ccccc2)ncc1Cc1cccnc1,,c1ccncc1,,,,test
US20070208054A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(CNCc1ccc(Br)cc1)OCc1ccccc1>>CC(C)(C)OC(=O)N(CC(=O)OCc1ccccc1)Cc1ccc(Br)cc1,,ClCCl,,,,test
US05002853,C=Cc1ccc(S(=O)(=O)Cl)cc1.CC(C)=O.O=C1c2ccccc2C(=O)N1O>>C=Cc1ccc(S(=O)(=O)[O-])cc1.O=C1c2ccccc2C(=O)N1O,,CCN(CC)CC,,,,test
US20080221110A1,CC1(C)OCC(CO)O1.Clc1cc(Cl)c(Cl)nn1>>CC1(C)OCC(COc2cc(Cl)nnc2Cl)O1,,C1CCOC1,,[H-].[Na+],,test
US20050009824A1,COc1cc2c(=O)n(CCN(C)C)c3c4cc5c(cc4ncc3c2cc1OC)OCO5>>COc1cc2c(cc1OC)-c1cnc3cc4c(cc3c1N(CCN(C)C)C2)OCO4,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05801170,CNc1cc([N+](=O)[O-])ccc1OC.O=C(Cl)CCl>>COc1ccc([N+](=O)[O-])cc1N(C)C(=O)CCl,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20060063783A1,O=S(=O)(Cl)/C=C/c1ccccc1.OC1CCNCC1>>O=S(=O)(/C=C/c1ccccc1)N1CCC(O)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20090156600A1,CCOC(=O)CC(=O)CC.Clc1ccc(CBr)cc1>>CCOC(=O)C(Cc1ccc(Cl)cc1)C(=O)CC,,C1CCOC1,O,CC(C)(C)O,CC(C)(C)[O-].[K+],test
US20050113580A1,COC(=O)CNCCc1cccc(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(c2ccccc2)c2ccccc2)c1.Cl>>Cl.O=C(O)CNCCc1cccc(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(c2ccccc2)c2ccccc2)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20070099990A1,CC(=Cc1ccc(C(C)C)cc1)CBr.Cc1ccc(O)cc1>>CC(=Cc1ccc(C(C)C)cc1)COc1ccc(C)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20080152763A1,Cn1c(=O)c2c(ncn2C)n(C)c1=O.O=C([O-])c1ccccc1.[Na+]>>Cn1c(=O)c2c(ncn2C)n(C)c1=O.O=C([O-])c1ccccc1.[Na+],,O,,,,test
US20090192138A1,CC#CCn1c(N2CCC[C@H](NC(=O)OC(C)(C)C)C2)c(C#N)c2c1c(=O)n(C)c(=O)n2C>>CC#CCn1c(N2CCC[C@H](N)C2)c(C#N)c2c1c(=O)n(C)c(=O)n2C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150175600A1,CC(C)(C)OC(=O)N[C@H]1CN(C(=O)OCc2ccccc2)CC[C@H]1O>>CC(C)(C)OC(=O)N[C@H]1CNCC[C@H]1O,[Pd],CCO,,,,test
US20050107354A1,CC(C)c1ccc(CCN)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)c1ccc(CCNC(=O)C(F)(F)F)cc1,,CN(C)C=O,O,CCN(CC)CC,Cl,test
US05234928,O=C(O)Cn1c(=O)c2cc(Cl)ccc2n(Cc2ccc(Cl)cc2Cl)c1=O.OCCBr>>O=C(Cn1c(=O)c2cc(Cl)ccc2n(Cc2ccc(Cl)cc2Cl)c1=O)OCCO,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20100273779A1,COc1ccc(-c2ccc(=O)n(C)n2)cc1>>Cn1nc(-c2ccc(O)cc2)ccc1=O,,ClCCl,,BrB(Br)Br,,test
US20120295903A1,Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CC=O)c2cc1C.NC1CCC(C(=O)O)C1>>Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCN[C@H]3CC[C@@H](C(=O)O)C3)c2cc1C,CC(=O)O,CO,,[BH3-]C#N.[Na+],,test
US05278184,O=C(CCCCCl)c1ccc(Cl)s1.Oc1ccc(C2=NCCO2)cc1>>O=C(CCCCOc1ccc(C2=NCCO2)cc1)c1ccc(Cl)s1,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US20110135650A1,CC(=O)O[C@@H](C(=O)OC(C)(C)C)[C@@H](OC(C)=O)C(=O)O.FC(F)(F)c1ccc(NCCCl)cc1>>CC(=O)O[C@@H](C(=O)OC(C)(C)C)[C@@H](OC(C)=O)C(=O)N(CCCl)c1ccc(C(F)(F)F)cc1,,ClCCl,c1ccncc1,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20150376166A1,Cn1cc(-c2cccc(NC(=O)N3Cc4ccc(Cl)cc4C3)c2C(C)(C)O[SiH2]C(C)(C)C)cc(Nc2ccc(C(=O)N3CCOCC3)cn2)c1=O>>Cn1cc(-c2cccc(NC(=O)N3Cc4ccc(Cl)cc4C3)c2CO)cc(Nc2ccc(C(=O)N3CCOCC3)cn2)c1=O,,CO,ClCCl,Cl,O=C([O-])O.[Na+],test
US04060528,Cc1cccc(C(=O)c2cccs2)c1Cl.O=C1CCC(=O)N1Br>>O=C(c1cccs1)c1cccc(CBr)c1Cl,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20080064704A1,CC(C)(C)OC(=O)CBr.CC1=C(C(=O)C2CCC2)C(c2ccc(C#N)cc2)NC(=O)N1c1cccc(C(F)(F)F)c1>>CC1=C(C(=O)C2CCC2)C(c2ccc(C#N)cc2)N(CC(=O)OC(C)(C)C)C(=O)N1c1cccc(C(F)(F)F)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040142926A1,Br.COc1ccc2nc(C)ccc2c1Br>>Br.Cc1ccc2c(Br)c(O)ccc2n1,,Br,,,,test
US20090076296A1,CCOC(=O)C1=C[C@@H](N=[N+]=[N-])[C@H](OS(C)(=O)=O)[C@H](OS(C)(=O)=O)C1.CCOP(OCC)OCC>>CCOC(=O)C1=C[C@H]2[C@@H]([C@H](OS(C)(=O)=O)C1)N2P(=O)(OCC)OCC,,Cc1ccccc1,,,,test
US20050256158A1,CC(=O)OCC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccccc21>>C[C@H]1C[C@@H](N(C(=O)CO)c2ccc(Cl)cc2)c2ccccc2N1,,CCO,O,Cl,[K+].[OH-],test
US20100189773A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=C(Nc1cnc2[nH]cc(Br)c2c1)OCc1ccccc1>>Cc1ccc(S(=O)(=O)n2cc(Br)c3cc(NC(=O)OCc4ccccc4)cnc32)cc1,,C1CCOC1,,[H-].[Na+],,test
US06635655B1,CC(C)(C)[Si](OCc1cccc(C#CCCCCO)c1)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](OCc1cccc(CCCCCCO)c1)(c1ccccc1)c1ccccc1,[Pd],CCOC(C)=O,,,,test
US20130324573A1,O=C=Nc1ccccc1F.Oc1ccc2c(c1)N(Cc1ccccc1)CCC2>>O=C(Nc1ccccc1F)Oc1ccc2c(c1)N(Cc1ccccc1)CCC2,,C1CCOC1,,CCN(CC)CC,,test
US20050288314A1,Cc1ccc(COc2cccc(F)c2C#N)cc1.N=C(N)N>>Cc1ccc(COc2cccc3nc(N)nc(N)c23)cc1,,CC(=O)N(C)C,,O=C(O)O,,test
US20160137639A1,CC(C)(C)CC1CC(c2onc(C[C@H](CCC(=O)O)C(=O)N3C(=O)OC[C@@H]3Cc3ccccc3)c2C2CC2)C1.CCI>>CCOC(=O)CC[C@@H](Cc1noc(C2CC(CC(C)(C)C)C2)c1C1CC1)C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20040068003A1,CI.O=c1c(-c2ccc(O)cc2)coc2cc(O)ccc12>>COc1ccc2c(=O)c(-c3ccc(O)cc3)coc2c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120058984A1,CC1=NNC(=O)CC1.O=Cc1cc(Nc2nc3cccnc3s2)nc(N[C@@H]2CC[C@@H](O)CC2)n1>>Cc1cc(Cc2cc(Nc3nc4cccnc4s3)nc(N[C@@H]3CC[C@@H](O)CC3)n2)c(=O)[nH]n1,,CCO,,Cl,[K+].[OH-],test
US20100130489A1,C[C@@H](NC(=O)OC(C)(C)C)C(=O)ON1C(=O)CCC1=O.OCCCNc1nc2cc(F)ccc2n2ccnc12>>C[C@@H](NC(=O)OC(C)(C)C)C(=O)OCCCNc1nc2cc(F)ccc2n2ccnc12,,CN(C)C=O,O,C1CCC2=NCCCN2CC1,,test
US20110312963A1,Fc1ccnc(Cl)c1.Nc1ccc(O)c2ccccc12>>Nc1ccc(Oc2ccnc(Cl)c2)c2ccccc12,,CN1CCCC1=O,O,Cl,CC(C)(C)[O-].[K+],test
US20020193614A1,N[C@H]1CC[C@H](O)CC1.O=C(NCc1ccc2c(c1)OCO2)c1cc([N+](=O)[O-])ccc1F>>O=C(NCc1ccc2c(c1)OCO2)c1cc([N+](=O)[O-])ccc1N[C@@H]1CC[C@@H](O)CC1,,c1ccncc1,,,,test
US20090306082A1,CCOC(=O)N1CCc2oc3c(OC)ccc(C=O)c3c2C1.NS(=O)(=O)O>>CCOC(=O)N1CCc2oc3c(OC)ccc(C(=O)O)c3c2C1,,CC(C)=O,O,[Na+].[O-]Cl,,test
US20090054407A1,CC(C)(C)OC(=O)n1c(-c2ccc(Cl)c3c2C(=O)NC3)cc2cc(C=O)ccc21.OCCOCCN1CCNCC1>>CC(C)(C)OC(=O)n1c(-c2ccc(Cl)c3c2C(=O)NC3)cc2cc(CN3CCN(CCOCCO)CC3)ccc21,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070105865A1,BrCCBr.Nc1cc([N+](=O)[O-])ccc1O>>O=[N+]([O-])c1ccc2c(c1)OCCN2,,[Na+],[OH-],CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20060217372A1,N#Cc1ccc(Oc2ccc(C=O)cc2)c(Cl)c1.OO>>NC(=O)c1ccc(Oc2ccc(C=O)cc2)c(Cl)c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20060199817A1,COS(=O)(=O)OC.Cc1ccc2c(NC(=O)C(F)(F)F)noc2c1I>>Cc1ccc2c(N(C)C(=O)C(F)(F)F)noc2c1I,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040132769A1,CCOC(=O)Nc1ccc2cc(OC(C)=O)ccc2c1.O=C1CCC(=O)N1Cl>>CCOC(=O)Nc1ccc2cc(OC(C)=O)ccc2c1Cl,,CC(=O)O,,Cl,,test
US20090312338A1,O=S(=O)(Cl)C1CC1.c1cc2c(ncc3[nH]nc(C4CCCNC4)c32)[nH]1>>O=S(=O)(C1CC1)N1CCCC(c2n[nH]c3cnc4[nH]ccc4c23)C1,,c1ccncc1,,,,test
US20050020590A1,COc1ccc(CN)cc1.N#Cc1cc(Br)ccc1F>>COc1ccc(CNc2cc(Br)ccc2C#N)cc1,,CS(C)=O,,CCN(CC)CC,,test
US06153768,COc1ccc(C2(C)CSc3cc(OC)ccc3C2=O)cc1>>CC1(c2ccc(O)cc2)CSc2cc(O)ccc2C1=O,,CC(=O)O,,Br,,test
US06498164B1,CC(C)CC(=O)Cl.CC(C)CCN1C(=O)CC(=O)N(CCC(C)C)C1=O>>CC(C)CCN1C(=O)C(C(=O)CC(C)C)C(=O)N(CCC(C)C)C1=O,,ClCCl,,c1ccncc1,,test
US05767293,COC1C(O)CCC2(CO2)C1C1(C)OC1CC=C(C)C.O=C(Cl)N1CCOCC1>>COC1C(OC(=O)N2CCOCC2)CCC2(CO2)C1C1(C)OC1CC=C(C)C,,CCOCC,,C1CCOC1,[H-].[Na+],test
US07348433B2,O=C(Cl)C(=O)Cl.O=C(O)CCc1ccc(Sc2ccc(Cl)cc2)cc1>>O=C(Cl)CCc1ccc(Sc2ccc(Cl)cc2)cc1,CN(C)C=O,ClCCl,,,,test
US05880162,Brc1cccc(Oc2ccccc2)c1.CC(=O)OCC(F)=CC(C)(C)c1ccc(OC(F)(F)F)cc1>>CC(C)(C=C(F)Cc1cccc(Oc2ccccc2)c1)c1ccc(OC(F)(F)F)cc1,,C1CCOC1,,[Mg],,test
US20120059162A1,CS(=O)(=O)c1nccn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12.NCC1CCOCC1>>O=C(NC1CC1)c1ccc(-c2cnc3c(NCC4CCOCC4)nccn23)cc1,,O,,C1COCCO1,,test
US04180666,CI.Cc1[nH]c(=O)c(C#N)c2c1C(=O)c1ccccc1-2>>Cc1c2c(c(C#N)c(=O)n1C)-c1ccccc1C2=O,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20110201613A1,O=C1c2ccccc2C(=O)N1OCc1cccc(N2C(=O)c3ccccc3C2=O)n1>>NOCc1cccc(N)n1,,C1CCOC1,,NN,O,test
US20100063038A1,COc1cc(-c2cc(CN3CCOCC3)n3ncnc(N)c23)ccc1NC(=O)OC(C)(C)C>>COc1cc(-c2cc(CN3CCOCC3)n3ncnc(N)c23)ccc1N,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070259965A1,NS(=O)(=O)c1ccc(F)cc1Cl.O=C1c2ccccc2C(=O)N1C[C@@H]1CO1>>O=C1c2ccccc2C(=O)N1C[C@@H](O)CNS(=O)(=O)c1ccc(F)cc1Cl,,CC(C)O,,c1ccncc1,,test
US06326369B1,CCOC(=O)C1(CCCCCCCC(=O)O)Cc2c(c(OC)c(OC)c(OC)c2OC)C1>>CCOC(=O)C1(CCCCCCCCO)Cc2c(c(OC)c(OC)c(OC)c2OC)C1,,C1CCOC1,,Cl,,test
US05510326,C=CCCl.CC(C=O)C(C)CC(C)(C)C>>C=CCC(C)(C=O)C(C)CC(C)(C)C,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20060128793A1,CN1CCNCC1.COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CC[C@H](O)[C@@]2(C)C[C@H]1OC(C)=O>>COC[C@H]1OC(=O)/C(=C/N2CCN(C)CC2)C2=C(O)C(=O)C3=C([C@H](OC(C)=O)C[C@@]4(C)C3CC[C@@H]4O)[C@]21C,,ClCCl,,,,test
US20050107364A1,CC(C(=O)O)c1ccccc1.CC[C@H](C)CCBr>>CC[C@H](C)CCC(C)(C(=O)O)c1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04431576,CC1(C)[C@H](/C=C2\CCOC2=O)[C@H]1C(=O)O.COC(=NC(C)C)NC(C)C>>COC(=O)[C@@H]1[C@@H](/C=C2\CCOC2=O)C1(C)C,,CCOC(C)=O,,,,test
US20070259924A1,NCc1cn(-c2ccc(N3CCCCC3=O)cc2)cn1.O=C(O)c1ccc(Cl)s1>>O=C(NCc1cn(-c2ccc(N3CCCCC3=O)cc2)cn1)c1ccc(Cl)s1,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US04616014,CCC=O.Cc1nc(NN)nnc1-c1ccccc1>>CCC=NNc1nnc(-c2ccccc2)c(C)n1,Cl,CO,,,,test
US20060016024A1,COc1c(N2CCOC2=O)cc(C)cc1N1CCOC1=O>>COc1c(NCCO)cc(C)cc1NCCO,,[K+],[OH-],,,test
US20080306055A1,CC(C)(C)OC(=O)N1CCC(CC(=O)O)CC1.NC(c1ccc(F)cc1)c1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCC(CC(=O)NC(c2ccc(F)cc2)c2ccc(F)cc2)CC1,,ClCCl,,ClCCCl,,test
US20120238564A1,CN1CCNCC1.Clc1nccn2c(-c3cccc(Br)n3)cnc12>>CN1CCN(c2nccn3c(-c4cccc(Br)n4)cnc23)CC1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US06110933,CC(C)CCCCCCCCCCC[C@H](O)CC(=O)N[C@@H](CCCC(=O)OCc1ccccc1)C(=O)O[C@@H](CCCCCCCCCCCC(C)C)CC(N)=O>>CC(C)CCCCCCCCCCC[C@H](O)CC(=O)N[C@@H](CCCC(=O)O)C(=O)O[C@@H](CCCCCCCCCCCC(C)C)CC(N)=O,[Pd],C1COCCO1,CO,O,,test
US04310526,CCc1c(/C=C/c2ccccc2)nc2ccc(C(=O)OC)cn2c1=O.C[S+](C)(C)=O>>CCc1c(/C=C/c2ccccc2)nc2n(c1=O)C1CC1(C(=O)OC)C=C2,,CN(C)C=O,,[H-].[Na+],,test
US20140343000A1,C=C(C)[C@@H]1CC[C@]2(N)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CC(C)(C)OC(=O)NCCC=O>>C=C(C)[C@@H]1CC[C@]2(NCCCNC(=O)OC(C)(C)C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1COCCO1,CCO,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US06218538B1,CCN(CC)CCOCC(=O)CC(=O)OCCCc1ccccc1.N#Cc1ccc(C=O)cc1.N=C(N)c1ccco1>>CCN(CC)CCOCC1=C(C(=O)OCCCc2ccccc2)C(c2ccc(C#N)cc2)N=C(c2ccco2)N1,,CN(C)C=O,,Cl,O=C([O-])O.[Na+],test
US20040248965A1,COc1ccc(C=O)cc1F.O=C1C=c2ccccc2=N1>>COc1ccc(C=C2C(=O)Nc3ccccc32)cc1F,C1CCNCC1,CCO,,,,test
US20040167123A1,Nn1c(=O)c(C2=NS(=O)(=O)c3cc(OCc4ccccc4)ccc3N2)c(O)c2ccccc21.O=C1CCC1>>O=c1c(C2=NS(=O)(=O)c3cc(OCc4ccccc4)ccc3N2)c(O)c2ccccc2n1N=C1CCC1,,CC(=O)N(C)C,,,,test
US20150232463A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc(C)c(-c2ccc(OCc3ccccc3)c(F)c2)c1N1CCC(C)(C)CC1>>Cc1nc(C)c([C@H](OC(C)(C)C)C(=O)O)c(N2CCC(C)(C)CC2)c1-c1ccc(OCc2ccccc2)c(F)c1,,CCO,O,[Li+].[OH-],,test
US20110263556A1,CC(C(=O)O)C(F)(F)F.COCCOc1ccc(NC(=O)c2cc(CN)ccc2Cl)cc1C(=O)Nc1ccc(Br)cc1>>COCCOc1ccc(NC(=O)c2cc(CNC(=O)C(C)C(F)(F)F)ccc2Cl)cc1C(=O)Nc1ccc(Br)cc1,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,test
US04897106,NC(=O)C(N)=NNc1cccc(COc2ccccc2)c1.O=Cc1ccccc1F>>NC(=O)C1=NN(c2cccc(COc3ccccc3)c2)C(c2ccccc2F)N1,,O,,CC(=O)O,,test
US20100305096A1,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCNCC3(C)C)n(C)c2n1.C[C@@H](O)C(=O)O>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCN(C(=O)[C@@H](C)O)CC3(C)C)n(C)c2n1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110245353A1,N#Cc1c(OC2C=CCCC2)cccc1[N+](=O)[O-].O=[Os](=O)(=O)=O>>N#Cc1c(OC2CCCC(O)C2O)cccc1[N+](=O)[O-],O=[Os](=O)(=O)=O,,,C1CCOC1,O,test
US20050222166A1,C1CNCCN1.Fc1ccc(C(OCCCCCl)c2ccc(F)cc2)cc1>>CCCC(OC(c1ccc(F)cc1)c1ccc(F)cc1)N1CCNCC1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090069340A1,CCn1c(C)c(Br)c(=O)n1C1CCCCC1.O=C1CCC(=O)N1Br>>Cn1c(CBr)c(Br)c(=O)n1C1CCCCC1,,ClC(Cl)(Cl)Cl,,,,test
US20060003968A1,NC(=S)NC1CC1.O=C(CBr)c1c[nH]c2ncccc12>>c1cnc2[nH]cc(-c3csc(NC4CC4)n3)c2c1,,CCO,,,,test
US20160272632A1,Cc1cc(Nc2nn([C@]3(CC#N)CCCOC3)c3ccnc(OCc4ccccc4)c23)ccc1C(=O)O>>Cc1cc(Nc2nn([C@]3(CC#N)CCCOC3)c3cc[nH]c(=O)c23)ccc1C(=O)O,[Pd],CCOC(C)=O,,,,test
US20070208001A1,Clc1cc(Br)cnc1N1CCCC2(CCNC2)C1.O=C=NC1CCCCC1>>O=C(NC1CCCCC1)N1CCC2(CCCN(c3ncc(Br)cc3Cl)C2)C1,,CC#N,CO,CCN(C(C)C)C(C)C,Cl,test
US05532248,CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(OCC(O)c4ccc5ccccc5c4)C(OC)C3)C(C)C(O[Si](C)(C)C(C)(C)C)CC1=O)C(C)CC2OC>>CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(OCC(O)c4ccc5ccccc5c4)C(OC)C3)C(C)C(O)CC1=O)C(C)CC2OC,,c1ccncc1,,,,test
US20070167622A1,CC(=O)c1ccccc1B(O)O.O=C(c1csc(Br)n1)N1CCCC2CCCCC21>>CC(=O)c1ccccc1-c1nc(C(=O)N2CCCC3CCCCC32)cs1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20030166637A1,COc1cccc2ccc(N3CCN(CCCCC4(C(=O)NCC(F)(F)F)c5ccccc5-c5ccccc54)CC3)nc12>>O=C(NCC(F)(F)F)C1(CCCCN2CCN(c3ccc4cccc(O)c4n3)CC2)c2ccccc2-c2ccccc21,,ClCCl,,BrB(Br)Br,,test
US20130029961A1,CN(C)c1ncc(N)cc1C(F)(F)F.O=C(Cl)Oc1ccccc1>>CN(C)c1ncc(NC(=O)Oc2ccccc2)cc1C(F)(F)F,,CC#N,O,c1ccncc1,,test
US20140142307A1,BrCc1ccc2ccccc2c1.Ic1nc[nH]c1I>>Ic1ncn(Cc2ccc3ccccc3c2)c1I,,C1CCOC1,,[K+].[OH-],,test
US20140371199A1,CN1CCNCC1.O=C(O)c1ccc(Br)cc1C(F)(F)F>>CN1CCN(C(=O)c2ccc(Br)cc2C(F)(F)F)CC1,,CCOC(C)=O,CN(C)C=O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080085886A1,C=COCCONC(=O)c1oc2ccncc2c1Nc1ccc(I)cc1F>>O=C(NOCCO)c1oc2ccncc2c1Nc1ccc(I)cc1F,,CCO,CO,Cl,O=C([O-])O.[Na+],test
US20130158041A1,CCI.Oc1cnc2ccc(Br)cc2c1>>CCOc1cnc2ccc(Br)cc2c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140213586A1,COc1cccc(N)c1.Cn1cc(C(=O)C(Cl)c2ccccc2)c2cc(F)ccc21>>COc1cccc(NC(C(=O)c2cn(C)c3ccc(F)cc23)c2ccccc2)c1,,CC#N,,,,test
US20080269210A1,C1COCCN1.Clc1nc(Cl)c2ccoc2n1>>Clc1nc(N2CCOCC2)c2ccoc2n1,,CO,,,,test
US20040010007A1,Cc1nc(N)c2nc(C)n(CCOCCN)c2c1C.O=C(Cl)N1CCOCC1>>Cc1nc(N)c2nc(C)n(CCOCCNC(=O)N3CCOCC3)c2c1C,,CCN(CC)CC,ClC(Cl)Cl,,,test
US20060041003A1,CCCCC12CCc3cc(OC)ccc3C1=CC(=O)C2>>CCCCC12CCc3cc(O)ccc3C1=CC(=O)C2,,ClCCl,,BrB(Br)Br,,test
US20110144129A1,CC[C@]1(C(=O)OC)C=C[C@@H](n2c(C)ccc2C)C1>>CC[C@]1(C(=O)O)C=C[C@@H](n2c(C)ccc2C)C1,,CO,,[Na+].[OH-],,test
US20080085890A1,COC=C1C(=O)NC(=O)c2ccc(Br)cc21.NCCc1c[nH]c2ccccc12>>O=C1NC(=O)c2ccc(Br)cc2/C1=C/NCCc1c[nH]c2ccccc12,,CN(C)C=O,,,,test
US20100179312A1,CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@H](n2cnc3c(On4nnc5ccccc54)ncnc32)C[C@@H]1O[Si](C)(C)C(C)(C)C.CO>>COc1ncnc2c1ncn2[C@H]1C[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO[Si](C)(C)C(C)(C)C)O1,,CO,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04643760,NS(=O)(=O)c1cccnc1Cl.OCC1CC1>>NS(=O)(=O)c1cccnc1OCC1CC1,,CCOC(C)=O,CN(C)C=O,Cl,[H-].[Na+],test
US20110257238A1,CCC1OC(=O)c2cnc(Cl)cc21.O=C1Cc2ccccc2N1>>CCC1OC(=C2C(=O)Nc3ccccc32)c2cnc(Cl)cc21,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20090318523A1,CCOC(=O)CCC(=O)OCC.COC(=O)c1ccc(C)c(C)c1C(=O)[O-]>>CCOC(=O)c1c(C(=O)OCC)c(O)c2cc(C)ccc2c1O,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20060040949A1,COc1ccc2nccc(OCC3CCC(NC(=O)OC(C)(C)C)CC3)c2c1>>COc1ccc2nccc(OC[C@@H]3CC[C@@H](N)CC3)c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120071467A1,CI.CN(CCCN(C)C(=O)c1ccc(NC(=O)OC(C)(C)C)cn1)C(=O)OCc1ccccc1>>CN(CCCN(C)C(=O)c1ccc(N(C)C(=O)OC(C)(C)C)cn1)C(=O)OCc1ccccc1,,C1CCOC1,,O,[H-].[Na+],test
US20050096337A1,Cc1nc(-c2ccc(OC(F)(F)F)cc2)ccc1CO.O=S(Cl)Cl>>Cc1nc(-c2ccc(OC(F)(F)F)cc2)ccc1CCl,,ClCCl,,,,test
US20030004161A1,COC(=O)c1cccc(Sc2nc(Nc3cc(C4CC4)n[nH]3)c3ccccc3n2)c1>>O=C(O)c1cccc(Sc2nc(Nc3cc(C4CC4)n[nH]3)c3ccccc3n2)c1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20080009488A1,C[Si](C)(C)CCOCn1ccc2cc(Br)ccc21.N#Cc1ccccc1C=O>>C[Si](C)(C)CCOCn1ccc2cc(C(O)c3ccccc3C#N)ccc21,,C1CCOC1,,[Li]CCCC,,test
US20110190227A1,CCOC(=O)Cc1cccc(Oc2ccc(Br)cc2CSc2ccccc2)c1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>CCOC(=O)Cc1cccc(Oc2ccc(-c3cnn(C)c3)cc2CSc2ccccc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20110301150A1,O=[N+]([O-])c1ccc(-c2cc(CO)on2)cc1>>Nc1ccc(-c2cc(CO)on2)cc1,[Pd],CCO,,[H][H],,test
US20020137933A1,CC(C)(O)c1ccc(S(N)(=O)=O)nc1>>C=C(C)c1ccc(S(N)(=O)=O)nc1,,O=C(O)C(F)(F)F,,,,test
US20090093484A1,Cc1cc(OC/C=C(\c2ccccc2)c2ccc(C#CCN3CCOCC3)cc2)ccc1OCC(=O)O.Cc1ccc(/C(=C/CO)c2ccc(I)cc2)cc1>>COC(=O)COc1ccc(OC/C=C(/c2ccc(C)cc2)c2ccc(I)cc2)cc1C,,C1CCOC1,Cc1ccccc1,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100331295A1,C1COCCN1.FC(F)(F)c1cc(-c2ccc(Br)cc2)n(CCCl)n1>>FC(F)(F)c1cc(-c2ccc(Br)cc2)n(CCN2CCOCC2)n1,,CC#N,,,,test
US05292742,CC=CCCCn1nnc(-c2ccc3[nH]c(CCCC)nc(=O)c3c2)n1.N#Cc1ccccc1-c1ccc(CBr)cc1>>C=CCCCCn1nnnc1-c1ccc2nc(CCCC)n(Cc3ccc(-c4ccccc4C#N)cc3)c(=O)c2c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120083469A1,CC(C)(C)OC(=O)N1Cc2ccccc2CC1CCC(=O)O.CNOC>>CON(C)C(=O)CCC1Cc2ccccc2CN1C(=O)OC(C)(C)C,,ClCCl,,Cl,O=C(n1ccnc1)n1ccnc1,test
US20120232056A1,COC(=O)c1ccc2nc(-c3ccc(F)cc3)c(Cl)nc2c1.NC1CCCCC1>>COC(=O)c1ccc2nc(-c3ccc(F)cc3)c(NC3CCCCC3)nc2c1,,CS(C)=O,O,CCN(C(C)C)C(C)C,,test
US06350757B1,CCOC(=O)C1(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)CCC1.Cl>>CCOC(=O)C1(C2NCCc3c2[nH]c2ccc(Cl)cc32)CCC1.Cl,,Cc1ccccc1,,O=P(Cl)(Cl)Cl,,test
US20020147334A1,COC(=O)CN.COc1cc(O)ccc1C=O>>COC(=O)CNCc1ccc(O)cc1OC,,CO,,Cl,[BH3-]C#N.[Na+],test
US20050119320A1,CCN=C=O.Cc1nc(N)sc1-c1ccc(S(C)(=O)=O)cc1>>CCNC(=O)Nc1nc(C)c(-c2ccc(S(C)(=O)=O)cc2)s1,,CN(C)C=O,,,,test
US20150299188A1,CC(C)=O.Cc1ccc(O)cc1[N+](=O)[O-].Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)Oc2ccc(C=O)c([N+](=O)[O-])c2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160122339A1,COc1ccnc2ccc(Br)cc12.Cn1cc(-c2ccc3nnc(S)n3c2)cn1>>COc1ccnc2ccc(Sc3nnc4ccc(-c5cnn(C)c5)cn34)cc12,,CN(C)C=O,,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,CCN(C(C)C)C(C)C,test
US20100222318A1,CC(=O)[O-].CN(C)C(=O)c1ccc(-c2cnc(N)c(-c3nnc(-c4ccc(CBr)cc4)o3)n2)cc1>>CC(=O)OCc1ccc(-c2nnc(-c3nc(-c4ccc(C(=O)N(C)C)cc4)cnc3N)o2)cc1,,CN(C)C=O,,Cl,,test
US20080070919A1,C1=CC[C@H]2CN[C@@H](C1)CN2c1ccc2ccccc2c1.Cc1ccc(OC[C@@H]2CO2)cn1>>Cc1ccc(OC[C@@H](O)CN2C[C@@H]3CC=CC[C@H]2CN3c2ccc3ccccc3c2)cn1,,CCO,,CCN(C(C)C)C(C)C,,test
US20150344481A1,CC(C)(C)OC(=O)N1CCn2cc(-c3ccc(F)cc3)nc2C1.O=C1CCC(=O)N1I>>CC(C)(C)OC(=O)N1CCn2c(nc(-c3ccc(F)cc3)c2I)C1,,ClCCl,O,,,test
US20090076020A1,COC(=O)CP(=O)(OC)OC.O=Cc1ccc(C(F)(F)F)nc1>>COC(=O)/C=C/c1ccc(C(F)(F)F)nc1,,C1CCOC1,,[H-].[Na+],,test
US05948817,COC(=O)c1c(-c2ccc(OC)cc2)ccc2c1OCO2>>COc1ccc(-c2ccc3c(c2C(=O)O)OCO3)cc1,,CCO,,[Na+].[OH-],,test
US05565586,CC(=O)CCl.O=[N+]([O-])c1ccc(O)cc1>>CC(=O)COc1ccc([N+](=O)[O-])cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US08815855B2,CC(C)(C)OC(=O)Nc1ccccc1N.O=C(O)/C=C/c1ccn(S(=O)(=O)c2ccc(Br)s2)c1>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)/C=C/c1ccn(S(=O)(=O)c2ccc(Br)s2)c1,,CCN(CC)CC,,CN(C)C=O,,test
US20140357858A1,Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1.S=C=Nc1ccccc1>>O=C1CC(=O)N(c2ccc(NC(=S)Nc3ccccc3)cc2)c2ccc3ccccc3c2N1,,C1CCOC1,,,,test
US20060247251A1,CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)NCN2c1ccccc1.N#Cc1ncc2cc(CCl)n(CCC3CCCCC3)c2n1>>CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)N(Cc1cc3cnc(C#N)nc3n1CCC1CCCCC1)CN2c1ccccc1,,CN(C)C=O,O,[H-].[Na+],,test
US20120316337A1,Br[Mg]c1cccc2ccccc12.COc1c(C(=O)O)ccc2ccccc12>>O=C(O)c1ccc2ccccc2c1-c1cccc2ccccc12,,C1CCOC1,,Cl,O,test
US20120077799A1,CC(C)(C)[Si](C)(C)Oc1ccc(C2=CC=CN3CCS(=O)(=O)N=C23)cc1>>O=S1(=O)CCN2C=CC=C(c3ccc(O)cc3)C2=N1,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20110201603A1,CCc1cc(C(n2cc(C(F)(F)F)cn2)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1cccc(N)c1.O=C(Cl)c1cccnc1Cl>>CCc1cc(C(n2cc(C(F)(F)F)cn2)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1cccc(NC(=O)c2cccnc2Cl)c1,,C1CCOC1,,O,c1ccncc1,test
US20050277670A1,BrCc1ccsc1.Cc1ncnc(C)c1C(=O)NCC[C@@H](C)N1CCC(Nc2ccc(Cl)cc2)CC1>>Cc1ncnc(C)c1C(=O)NCC[C@@H](C)N1CCC(N(Cc2ccsc2)c2ccc(Cl)cc2)CC1,,CC#N,,,,test
US20160075711A1,CCCC[Sn](CCCC)(CCCC)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.O=Cc1c(F)cncc1Br>>O=Cc1c(F)cncc1-c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1,,CC#N,O,,,test
US20130005706A1,ClP(Cl)(Cl)(Cl)Cl.O=C1NCCOc2ccc(-c3ccc(C(F)(F)F)cc3)cc21>>FC(F)(F)c1ccc(-c2ccc3c(c2)C(Cl)=NCCO3)cc1,,Cc1ccccc1,,,,test
US05780492,CC#CCC(CNc1cccc(Cl)c1)NCc1cncn1Cc1ccc(C#N)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC#CCC1CN(c2cccc(Cl)c2)C(=O)N1Cc1cncn1Cc1ccc(C#N)cc1.Cl.Cl,,C1CCOC1,,CCN(CC)CC,CCOC(C)=O,test
US20040077605A1,CC(=O)O.O=[N+]([O-])c1cccc2c(F)cccc12>>CC(=O)Nc1cccc2c(F)cccc12,[Fe],CC(=O)O,,CC(=O)OC(C)=O,,test
US20070129562A1,COc1ccc(C(CN)C2(O)CCCCC2)cc1.Cl>>COc1ccc(C(CN)C2(O)CCCCC2)cc1.Cl,,CCOC(C)=O,,CC(C)O,,test
US20090239941A1,CCC(C)(C)C(=O)Oc1ccc(C[C@H](NC(=O)OC(C)(C)C)C(N)=O)cc1OC(=O)C(C)(C)CC.Cl>>CCC(C)(C)C(=O)Oc1ccc(C[C@H]([NH3+])C(N)=O)cc1OC(=O)C(C)(C)CC.[Cl-],,C1COCCO1,ClCCl,,,test
US20090209607A1,CCCc1sc(C(=O)OC)cc1Br.Cn1nccc1B1OC(C)(C)C(C)(C)O1>>CCCc1sc(C(=O)OC)cc1-c1ccnn1C,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,,,O=C([O-])[O-].[K+].[K+],,test
US05019154,Cc1ccc2c(c1Cl)C(=O)N(C1(C#N)CCCCC1)C2=O.O=S(=O)(O)O>>Cc1ccc2c(c1Cl)C(=O)N(C1(C(N)=O)CCCCC1)C2=O,,ClCCl,,O,,test
US20040077642A1,Brc1ccc(N2CCOCC2)cc1.CON(C)C(=O)c1ccc(Br)cc1>>O=C(c1ccc(Br)cc1)c1ccc(N2CCOCC2)cc1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20110039866A1,NC(=O)c1cc(Br)co1.O=CC(Cl)(Cl)Cl>>O=C(NC(O)C(Cl)(Cl)Cl)c1cc(Br)co1,,Cc1ccccc1C,,,,test
US20010031778A1,Cc1ccc(S(=O)(=O)OC(CO)CO)cc1.O=C/C=C/C=C/c1ccc(C(F)(F)F)cc1>>Cc1ccc(S(=O)(=O)O[C@H]2CCO[C@@H](/C=C/C=C/c3ccc(C(F)(F)F)cc3)O2)cc1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20130035318A1,C=C(C)[C@@H]1CC[C@]2(NCCN3CCS(=O)(=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NCCN3CCS(=O)(=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1COCCO1,,[Na+].[OH-],,test
US20140288123A1,COC(=O)c1ccc(C(C)O)cc1.Oc1cccc(F)c1>>COC(=O)c1ccc(C(C)Oc2cccc(F)c2)cc1,,C1CCOC1,O,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04298602,NC(=O)NN(C(=O)c1ccccc1)c1ccccn1>>Oc1nc(-c2ccccc2)n(-c2ccccn2)n1,,CC(=O)O,,[Na+].[OH-],,test
US20070117840A1,CC(C)(C)Cn1c(C(=O)OC(C)(C)C)c(O)c2cc(Cl)c(Cl)cc2c1=O.CCCCO>>CCCCOc1c(C(=O)OC(C)(C)C)n(CC(C)(C)C)c(=O)c2cc(Cl)c(Cl)cc12,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20020198376A1,COCCN(CCO[Si](C)(C)C(C)(C)C)C(=O)N[C@@H](C)C(=O)OC(C)(C)C>>COCCN(CCO)C(=O)N[C@@H](C)C(=O)OC(C)(C)C,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20050197359A1,CC(C)(C)[Si](C)(C)Cl.COC(=O)[C@@]1(C)[C@@H](O)CCN1C(=O)OC(C)(C)C>>COC(=O)[C@@]1(C)[C@@H](O[Si](C)(C)C(C)(C)C)CCN1C(=O)OC(C)(C)C,,ClCCl,,c1c[nH]cn1,,test
US20150225401A1,COC(=O)c1ccc(CBr)cc1.O=C(N(CC1CNC1)[C@@H]1C[C@H]1c1ccccc1)C(F)(F)F>>COC(=O)c1ccc(CN2CC(CN(C(=O)C(F)(F)F)[C@@H]3C[C@H]3c3ccccc3)C2)cc1,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20060135566A1,Cc1cccc(C(=O)C(Br)c2ccnc(N)c2)c1.NC(=S)c1ccc(F)cc1>>Cc1cccc(-c2nc(-c3ccc(F)cc3)sc2-c2ccnc(N)c2)c1,,CN(C)C=O,,Br,O=C([O-])O.[Na+],test
US20050080262A1,BrCCCBr.COC(=O)c1ccc(O)c(OC)c1>>COC(=O)c1ccc(OCCCBr)c(OC)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070149514A1,O=Cc1c[nH]c2ccc(Br)cc12.OB(O)c1ccc(C(F)(F)F)cc1>>O=Cc1c[nH]c2ccc(-c3ccc(C(F)(F)F)cc3)cc12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20070099944A1,CC1=C(C(=O)O)C(c2cc(F)cc(F)c2)NC(=O)N1.Nc1ccc2[nH]nc(-c3ccc(F)cc3)c2c1>>CC1=C(C(=O)Nc2ccc3[nH]nc(-c4ccc(F)cc4)c3c2)C(c2cc(F)cc(F)c2)NC(=O)N1,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20040259926A1,CI.COc1cc2c(Oc3ccc(C4CCCCC4)cc3)c(C(=O)NC#N)sc2cc1C>>COc1cc2c(Oc3ccc(C4CCCCC4)cc3)c(C(=O)N(C)C#N)sc2cc1C,,CN(C)C=O,,[H-].[Na+],,test
US07160887B1,C[C@@H](NC(=O)OC(C)(C)C)c1cccc(O)c1.O=[N+]([O-])c1ccc(Cl)cc1F>>C[C@@H](NC(=O)OC(C)(C)C)c1cccc(Oc2cc(Cl)ccc2[N+](=O)[O-])c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20120186446A1,OCC(O)CCl.c1ccc(Cn2ccnc2)cc1>>OCC(O)C[n+]1ccn(Cc2ccccc2)c1.[Cl-],,CO,,,,test
US05883094,CC(C)(C)OC(=O)N1CCNCC1.O=c1[nH]c2ccccc2n1CCCCl>>CC(C)(C)OC(=O)N1CCN(CCCn2c(=O)[nH]c3ccccc32)CC1,,CCO,,CCN(C(C)C)C(C)C,O,test
US05962685,CCOc1oc(-c2c(F)cccc2Cl)nc1C(C)C.OCc1ccccc1>>CCOc1oc(-c2c(Cl)cccc2OCc2ccccc2)nc1C(C)C,,CN(C)C=O,,[H][H],[H-].[Na+],test
US20100120770A1,CC(C)(C)OC(=O)N1CCC(C#N)(c2ccccc2)CC1>>CC(C)(C)OC(=O)N1CCC(CN)(c2ccccc2)CC1,O=[Pt],CC(=O)O,CCO,,,test
US20150210720A1,BrCCOCc1ccccc1.O=C(O)c1coc2c1C(=O)NCC2>>O=C(O)c1coc2c1C(=O)N(CCOCc1ccccc1)CC2,,CN(C)C=O,,O,[H-].[Na+],test
US20110015200A1,COC(=O)C1CCC(=O)N1CC#N>>O=C1NCCN2C(=O)CC=C12,O=[Pt]=O,CO,,,,test
US20090186870A1,C1COCCN1.C=CS(=O)(=O)c1ccc2nc(NC(=O)NC(=O)c3ccccc3Cl)sc2c1>>O=C(NC(=O)c1ccccc1Cl)Nc1nc2ccc(S(=O)(=O)CCN3CCOCC3)cc2s1,,C1CCOC1,,,,test
US20040053908A1,Nc1cc(Oc2ccc([N+](=O)[O-])cc2)ncn1>>Nc1ccc(Oc2cc(N)ncn2)cc1,[Fe],O,,CCO,[Cl-].[NH4+],test
US20150111894A1,COc1cc(-n2ccc3oc(Br)cc3c2=O)ccc1OCC1(C#N)CC1.COc1ccc(B(O)O)cc1>>COc1ccc(-c2cc3c(=O)n(-c4ccc(OCC5(C#N)CC5)c(OC)c4)ccc3o2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20120225888A1,CC#N.CCOC(=O)c1ccc2c(c1)CCCC2>>N#CCC(=O)c1ccc2c(c1)CCCC2,,C1COCCO1,O,Cl,[H-].[Na+],test
US20150284394A1,CC(C)(C)OC(=O)C1Nc2ncnc(Cl)c2C1O>>CC(C)(C)OC(=O)c1cc2c(Cl)ncnc2[nH]1,,CN(C)C=O,,[H-].[Na+],,test
US04493803,C=CP(=O)([O-])OCC.CCOC(OCC)OCC>>C=CP(=O)(OCC)OCC,,CCO,,CCOC(C)=O,,test
US20060128790A1,COc1cc2c(c(C)c1C)N(C(C)=O)CC1(CCC1)C2>>Cc1c(O)cc2c(c1C)N(C=O)CC1(CCC1)C2,,ClCCl,,BrB(Br)Br,,test
US20050038072A1,Cl.O=C(Cc1ccc(CN2CCC(=O)C(C(c3ccccc3)c3ccccc3)C2)cc1)OCC(=O)c1ccccc1>>Cl.O=C(O)Cc1ccc(CN2CCC(=O)C(C(c3ccccc3)c3ccccc3)C2)cc1,,C1CCOC1,,[Na+].[OH-],,test
US20040186160A1,O=C1Cc2ccc(-c3ccccc3)cc2N1.O=Cc1[nH]c2c(c1CCC(=O)O)CCCCC2>>O=C(O)CCc1c(/C=C2\C(=O)Nc3cc(-c4ccccc4)ccc32)[nH]c2c1CCCCC2,,CCO,,C1CCNCC1,,test
US05593969,CC(C)(C)[Si](C)(C)Cl.CCCCCCCCCCC[C@@H](O)CCO>>CCCCCCCCCCC[C@@H](O)CCO[Si](C)(C)C(C)(C)C,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US06110962,COC(=O)[C@@H](O)Cc1ccccc1.Oc1c(Br)cc(-c2c3ccccc3c(C(F)(F)F)c3sc4ccccc4c23)cc1Br>>O=C(O)[C@@H](Cc1ccccc1)Oc1c(Br)cc(-c2c3ccccc3c(C(F)(F)F)c3sc4ccccc4c23)cc1Br,,CO,,BrBr,,test
US05998665,CC(C)Nc1nc(Cl)cc(NS(=O)(=O)c2ccc(N)cc2)n1.CCN>>CCNc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(NC(C)C)n1,,CCO,,,,test
US20150111734A1,C=CCCC1CCNC1=O.CCN(C(=O)CCI)c1cn(-c2cccnc2)nc1Cl>>C=CCCC1CCN(CCC(=O)N(CC)c2cn(-c3cccnc3)nc2Cl)C1=O,,CN(C)C=O,,O,[H-].[Na+],test
US20110311461A1,Nc1ccccc1.O=CC(=O)O.OB(O)c1cc2ccccc2s1>>O=C(O)C(Nc1ccccc1)c1cc2ccccc2s1,,CC#N,,O,,test
US05985799,Cc1cc(SCCC(=O)O)c(C)cc1Br>>Cc1cc(Br)c(C)c2c1SCCC2=O,,ClCCl,,O=S(=O)(O)O,,test
US20110071126A1,C=C(OCC)C1(NS(=O)C(C)(C)C)c2cc(Br)ccc2CC12CCC(OC)CC2.CC(C)(C)OC(=O)OC(=O)[O-]>>CCOC(=O)C1(NS(=O)C(C)(C)C)c2cc(Br)ccc2CC12CCC(OC)CC2,CN(C)c1ccncc1,C1CCOC1,,,,test
US20060235226A1,CC(=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1ccccc1>>C=C1C(=O)N[C@@H](Cc2ccccc2)C(=O)N1Cc1ccccc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20020120144A1,Clc1cc2nc[nH]c2cc1Cl.O=Cc1ccc(F)cc1>>O=Cc1ccc(-n2cnc3cc(Cl)c(Cl)cc32)cc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060148888A1,CN(C(=O)OC(C)(C)C)C1CCN(CCC2CCOc3cc(S(=O)(=O)c4cccc(F)c4)ccc32)C1>>CNC1CCN(CCC2CCOc3cc(S(=O)(=O)c4cccc(F)c4)ccc32)C1,,CCO,Cl,,,test
US20090253699A1,CCOC(=O)c1cccc(C(=O)NCC(=O)c2ccc(C(C)C)cc2)c1.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CCOC(=O)c1cccc(-c2ncc(-c3ccc(C(C)C)cc3)s2)c1,,c1ccncc1,,N,,test
US20140315888A1,CCOC(=O)C(=O)OCC.Nc1cc([N+](=O)[O-])cnc1N>>O=[N+]([O-])c1cnc2nc(O)c(O)nc2c1,,CCOCC,,,,test
US20050203094A1,COCC(COC)(C(=O)OC)c1ccc(O)c(C=O)c1.O=C1CCC(=O)N1Br>>COCC(COC)(C(=O)OC)c1cc(Br)c(O)c(C=O)c1,,CN(C)C=O,,,,test
US20160022619A1,CCOC(=O)[C@@H]1C[C@@H]1c1ccc(N(CCC(F)(F)F)C2CCCCC2)c(N)c1.Nc1cncnc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCOC(=O)[C@@H]1C[C@@H]1c1ccc(N(CCC(F)(F)F)C2CCCCC2)c(NC(=O)Nc2cncnc2)c1,,C1CCOC1,,CCN(CC)CC,,test
US20050038035A1,Cc1ccc(C)n1-c1cccc(CC(=O)N2CCc3cc(N)ccc32)n1.O=C(O)C1=C(c2ccc(F)cc2)CCCC1>>Cc1ccc(C)n1-c1cccc(CC(=O)N2CCc3cc(NC(=O)C4=C(c5ccc(F)cc5)CCCC4)ccc32)n1,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US05614633,FCC1(CF)Oc2ccc(C(F)(F)C(F)(F)F)cc2C2OC21.Oc1ccccn1>>O[C@H]1[C@H](Oc2ccccn2)c2cc(C(F)(F)C(F)(F)F)ccc2OC1(CF)CF,,CCO,,c1ccncc1,,test
US05298517,CCCCc1nc(Cl)c(C(C)=O)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1.C[Mg]Br>>CCCCc1nc(Cl)c(C(C)(C)O)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,C1CCOC1,,,,test
US05112998,CC(=O)OC(C)=O.CC[C@H]1CC[C@H]2[C@@H]3[C@@H]4O[C@]45OC4=C5[C@](C)(CC[C@@H]4O)[C@H]3CC[C@]12C>>CC[C@H]1CC[C@H]2[C@@H]3[C@@H]4O[C@]45OC4=C5[C@](C)(CC[C@@H]4OC(C)=O)[C@H]3CC[C@]12C,,ClCCl,,c1ccncc1,,test
US20100113391A1,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].N#CCCCn1c(=O)c2cc(F)c(NC3CCCCC3)cc2n(C2CCCC2)c1=O>>O=c1c2cc(F)c(NC3CCCCC3)cc2n(C2CCCC2)c(=O)n1CCCc1nnn[nH]1,,C1COCCO1,,[Na+].[OH-],,test
US20120065196A1,CC(C)(C)OC(=O)N1CCC(=O)C(Br)C1.NC(=S)c1ccccc1>>Br.c1ccc(-c2nc3c(s2)CNCC3)cc1,,CCOC(C)=O,,,,test
US20050137213A1,COc1ccc(O)cc1.Clc1ncnc2ccccc12>>COc1ccc(Oc2ncnc3ccccc23)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20140031336A1,COC(=O)c1ccc(-c2ccc3c(c2)[C@H](Nc2ccc([N+](=O)[O-])cn2)C[C@H](C)N3C(C)=O)cc1>>COC(=O)c1ccc(-c2ccc3c(c2)[C@H](Nc2ccc(N)cn2)C[C@H](C)N3C(C)=O)cc1,[Pd],CO,,O=C[O-].[NH4+],,test
US20120172382A1,O=[N+]([O-])c1cc(Cl)c(Oc2ccncc2Br)cc1F>>Nc1cc(Cl)c(Oc2ccncc2Br)cc1F,[Fe],CCO,O,[Cl-].[NH4+],,test
US20080146523A1,c1ccc(COc2ccccc2OCc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)cc1>>c1ccc(COc2ccccc2OCc2c[nH]cn2)cc1,,CO,,CC(=O)O,,test
US20070135452A1,CNc1c(N)cccc1NC(=S)Nc1c(C)cc(C)cc1C>>Cc1cc(C)c(Nc2nc3cccc(N)c3n2C)c(C)c1,Cl[Hg]Cl,CC#N,CCOC(C)=O,,,test
US20110135668A1,CC(C)S(=O)(=O)c1ccccc1Nc1nc(Cl)nc2ncn(C)c12.Cc1cc(N)c(OC(C)C)cc1C1CCN(C)CC1>>Cc1cc(Nc2nc(Nc3ccccc3S(=O)(=O)C(C)C)c3c(ncn3C)n2)c(OC(C)C)cc1C1CCN(C)CC1,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20160096832A1,CC(C)(C)c1ccc(I)cc1.Nc1ncc2c(n1)CCN(c1ccc[nH]c1=O)C2>>CC(C)(C)c1ccc(-n2cccc(N3CCc4nc(N)ncc4C3)c2=O)cc1,[Cu]I,CN1CCCC1=O,,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20120245344A1,CC(C)(C)OC(=O)N1CCC(O)(c2cnc(CO[Si](C)(C)C(C)(C)C)c(Cl)c2)CC1.CCN(CC)S(F)(F)F>>CC(C)(C)OC(=O)N1CCC(F)(c2cnc(CO[Si](C)(C)C(C)(C)C)c(Cl)c2)CC1,,ClCCl,,O,,test
US20110288014A1,CI.Cc1cccnc1>>Cc1ccc[n+](C)c1.[I-],,CC#N,,COC(C)(C)C,,test
US04469885,CC(C)(CO)NC(=O)c1ccc(Br)cc1>>CC1(C)COC(c2ccc(Br)cc2)=N1,,CCOCC,,O=S(Cl)Cl,,test
US20060189593A1,Nc1ccc2c(c1)CC1(C2)NC(=O)NC1=O.O=S(=O)(Cl)c1cccc2ccccc12>>O=C1NC(=O)C2(Cc3ccc(NS(=O)(=O)c4cccc5ccccc45)cc3C2)N1,,C1CCOC1,,CCN(CC)CC,,test
US07244722B2,CC(C)(C)OC(=O)N1CCN(c2ncc[nH]c2=O)CC1.Fc1cc(F)c(CBr)cc1F>>CC(C)(C)OC(=O)N1CCN(c2nccn(Cc3cc(F)c(F)cc3F)c2=O)CC1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20040259923A1,CC(=O)Nc1nc(C(=O)Nc2ccc(N)cc2)cs1.N#CN>>CC(=O)Nc1nc(C(=O)Nc2ccc(NC(=N)N)cc2)cs1,,COCCO,,Cl,,test
US20130065861A1,CCCCCCCCCCCCCCCCOC[C@H](CSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](CC)C(=O)N[C@H](CCC(=O)O)C(N)=O)OCCCCCCCCCCCCCCCC>>CCCCCCCCCCCCCCCCOC[C@H](CSC[C@H](N)C(=O)N[C@@H](CC)C(=O)N[C@H](CCC(=O)O)C(N)=O)OCCCCCCCCCCCCCCCC,,CC#N,,C1CCNCC1,,test
US20090023731A1,Nc1cccc(OCCCN2CCOCC2)c1.O=C=NC1CCCCC1>>O=C(Nc1cccc(OCCCN2CCOCC2)c1)NC1CCCCC1,,ClC(Cl)Cl,,,,test
US06002008,CC(C)c1cccc(Nc2c(C#N)cnc3ccc([N+](=O)[O-])cc23)c1>>CC(C)c1cccc(Nc2c(C#N)cnc3ccc(N)cc23)c1,[Pd],CCO,,NN,,test
US20110213143A1,CC(C)(C)OC(=O)N1CCC/C(=C\c2ncn3c2CCc2ccccc2-3)C1=O>>CC(C)(C)OC(=O)N1CCCC(Cc2ncn3c2CCc2ccccc2-3)C1=O,[Pd],C1CCOC1,CO,,,test
US20150005293A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1sc(N)nc1C(F)(F)F>>CCOC(=O)c1sc(NC(=O)OC(C)(C)C)nc1C,,C1CCOC1,,,,test
US04946951,CC(C)(C)OC(=O)NCC(=O)OC[C@H]1O[C@@H](n2cc(F)c(=O)[nH]c2=O)C[C@@H]1OCc1ccc(Cl)cc1.Cl>>Cl.NCC(=O)OC[C@H]1O[C@@H](n2cc(F)c(=O)[nH]c2=O)C[C@@H]1OCc1ccc(Cl)cc1,,C1COCCO1,Cl,,,test
US20030166644A1,CC(C)(C)CCNC(=O)c1ccc(OC(=O)Cl)cc1.c1cncc(CN2CCNCC2)c1>>CC(C)(C)CCNC(=O)c1ccc(OC(=O)N2CCN(Cc3cccnc3)CC2)cc1,,ClCCl,,,,test
US20060100226A1,COc1cccc(-c2nc(SCc3cccc(N)c3)[nH]c(=O)c2C#N)c1.O=C=Nc1cc(F)cc(F)c1>>COc1cccc(-c2nc(SCc3cccc(NC(=O)Nc4cc(F)cc(F)c4)c3)[nH]c(=O)c2C#N)c1,,C1CCOC1,,CN(C)c1ccccn1,,test
US20160264552A1,CC(C)(C)OC(=O)NCC(=O)O.Nc1cccc(Nc2ncc(Cl)c(-c3cn(S(=O)(=O)c4ccccc4)c4ccccc34)n2)c1>>CC(C)(C)OC(=O)NCC(=O)Nc1cccc(Nc2ncc(Cl)c(-c3cn(S(=O)(=O)c4ccccc4)c4ccccc34)n2)c1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040259957A1,CCCOc1ccc(C=O)cc1.COc1cc(C(C)=O)cc(OC)c1OC>>CCCOc1ccc(/C=C/C(=O)c2cc(OC)c(OC)c(OC)c2)cc1,,CO,,[Na+].[OH-],,test
US20140303164A1,Cn1nc(N)c2c(Cl)ccc(B3OC(C)(C)C(C)(C)O3)c21.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cn1nc(NS(=O)(=O)C(F)(F)F)c2c(Cl)ccc(B(O)O)c21,,ClCCl,,CCN(CC)CC,,test
US20100047367A1,CCOC(=O)CC(=O)Cl.CCOC(=O)c1cc2ccc(C(F)(F)F)cc2n1NCc1ccc(F)cc1>>CCOC(=O)CC(=O)N(Cc1ccc(F)cc1)n1c(C(=O)OCC)cc2ccc(C(F)(F)F)cc21,,C1COCCO1,,,,test
US20100137313A1,CS(=O)(=O)c1nc(Nc2ccc(F)c(Cl)c2)ncc1Br.Cc1cc(C)[nH]n1>>Cc1cc(C)n(-c2nc(Nc3ccc(F)c(Cl)c3)ncc2Br)n1,,CN(C)C=O,,O,[H-].[Na+],test
US20140350019A1,Cc1cc(-c2cccc(F)c2)cc(C(=O)Nc2c(F)ccc(O)c2C)c1F>>Cc1cc(-c2cccc(F)c2)cc(CNc2c(F)ccc(O)c2C)c1F,,C1CCOC1,,,,test
US20070155805A1,CCOC(=O)C(C)(C)Oc1ccc(O)cc1C.Cc1c(CCCBr)sc2cc(Br)ccc12>>CCOC(=O)C(C)(C)Oc1ccc(OCCCc2sc3cc(Br)ccc3c2C)cc1C,,CC#N,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20070167452A1,[N-]=[N+]=NCC1CCC(COc2ccccc2)OC1>>NCC1CCC(COc2ccccc2)OC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130244929A1,CCCCCCCCCCc1ccc2cc(C(=O)OC)ccc2c1>>CCCCCCCCCCc1ccc2cc(C(=O)O)ccc2c1,,C1CCOC1,CO,[Li+].[OH-],,test
US20140039219A1,O=C(Cl)OCc1ccc([N+](=O)[O-])cc1.O=C1CCCCCN1.[OH-]>>O=C(O)CCCCCNC(=O)OCc1ccc([N+](=O)[O-])cc1,,[Na+],[OH-],O,,test
US04150226,CN=C=O.Cc1cc(N)sn1>>CNC(=O)Nc1cc(C)ns1,,C1CCOC1,,,,test
US20080139817A1,N#Cc1cccnc1Cl.SCc1ccccc1>>N#Cc1cccnc1SCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080207654A1,CCCCc1nc(C(C)C)n(-c2ccc3c(c2)CCO3)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nc(C(C)C)n(-c2ccc3c(c2)CCO3)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20100145047A1,CCOC(=O)N1CC[C@H](Nc2ccc(N)cn2)C1.O=C(Cl)C(=O)Cl.O=C(O)c1cc2cc(Br)ccc2s1>>CCOC(=O)N1CC[C@H](Nc2ccc(NC(=O)c3cc4cc(Br)ccc4s3)cn2)C1.Cl,CN(C)C=O,ClCCl,,CCN(CC)CC,,test
US20060094767A1,ClCC1CO1.O=[N+]([O-])c1c[nH]c(Cl)n1>>O=[N+]([O-])c1cn(CC(O)CCl)c(Cl)n1,,CC#N,,O=C([O-])O.[Na+],,test
US20040248949A1,CCOC(=O)[C@@H]1CCCC[C@@H]1NC(=O)c1ccc(O)cc1.ClCCN1CCOCC1>>CCOC(=O)[C@@H]1CCCC[C@@H]1NC(=O)c1ccc(OCCN2CCOCC2)cc1,,CCOC(C)=O,CN(C)C=O,Cl,O=C([O-])[O-].[K+].[K+],test
US20140094459A1,CC(C)(C)OC(=O)N1CCCC1Cn1cc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc21>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1F)cn2CC1CCCN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05281593,Brc1cccc2cc[nH]c12.CN(C)C=O>>O=Cc1cccc2cc[nH]c12,,C1CCOC1,O,CCCCCC,[Li]CCCC,test
US20040058894A1,CCCCCC[Mg]Br.O=Cc1cccc(Br)c1>>CCCCCCC(O)c1cccc(Br)c1,,C1CCOC1,,,,test
US20150005289A1,CC(C)(C)OC(=O)N1CC=C(c2cn3c(=O)cc(O)nc3cn2)CC1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CC=C(c2cn3c(=O)cc(OS(=O)(=O)C(F)(F)F)nc3cn2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20080085901A1,CCOC(=O)c1nc(N)sc1I>>CCOC(=O)c1ncsc1I,,C1CCOC1,,CC(C)(C)ON=O,,test
US20040254241A1,CCCCCCCCC[N-]CCC(C)=O.COCOc1ccc(C=O)cc1>>CCCCCCCCCNC(=O)/C(=C\c1ccc(OCOC)cc1)C(C)=O,,Cc1ccccc1,O,C1CCNCC1,CC(=O)O,test
US20060106048A1,COC(=O)Cc1ccc(C#N)cc1[N+](=O)[O-]>>COC(=O)Cc1ccc(C#N)cc1N,[Pd],Cc1ccccc1,,O=S(=O)([O-])[O-].[Mg+2],,test
US03971772,CS(=O)(=O)Cl.C[C@]12C=CC(=O)C=C1CC[C@H]1[C@@H]3C[C@@H](OCCO)[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]12>>C[C@]12C=CC(=O)C=C1CC[C@H]1[C@@H]3C[C@@H](OCCOS(C)(=O)=O)[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]12,,c1ccncc1,,Cl,,test
US20120264737A1,COC(=O)c1cc(NC(=O)NCC(C)C)n(C)n1>>CC(C)CNC(=O)Nc1cc(C(=O)O)nn1C,,CO,,O,[Li+].[OH-],test
US20090156610A1,Cc1ccc(S(=O)(=O)OCC2(C)COC2)cc1.O=Cc1cc(Br)ccc1O>>CC1(COc2ccc(Br)cc2C=O)COC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070197537A1,C=O.O=C(Nc1ccc(Oc2ccnc3cc(C4CCNCC4)sc23)c(F)c1)c1ccnn(-c2ccc(F)cc2)c1=O>>CN1CCC(c2cc3nccc(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)c3s2)CC1,,C1CCOC1,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090163588A1,FCCBr.N#Cc1ccc(N)cc1C(F)(F)F>>N#Cc1ccc(NCCF)cc1C(F)(F)F,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130203754A1,Cc1ccn2c(CC(=O)O)c(-c3ccc(Cl)cc3)nc2c1.NCCCc1ccccc1>>CCN(Cc1ccccc1)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2cc(C)ccn12,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20090270405A1,Cc1ccc2nc(N)sc2c1.S=C(n1ccnc1)n1ccnc1>>Cc1ccc2nc(NC(=S)n3ccnc3)sc2c1,,CC#N,,,,test
US20100076014A1,CC(=O)OCC(C)(C(=O)Nc1nncs1)C(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1>>CC(CO)(C(=O)Nc1nncs1)C(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1,,CC#N,,Cl,,test
US20160120841A1,Cc1ccc2c(c1)O[C@@H](c1cccc(C(=O)O)c1)C[C@H]2NC(=O)C1(c2ccc3c(c2)OC(F)(F)O3)CC1.O[C@@H]1CCNC1>>Cc1ccc2c(c1)O[C@@H](c1cccc(C(=O)N3CC[C@@H](O)C3)c1)C[C@H]2NC(=O)C1(c2ccc3c(c2)OC(F)(F)O3)CC1,,CC(=O)N(C)C,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20020091261A1,Clc1nnc(Cc2ccncc2)c2ccccc12.NC1CCCCC1>>c1ccc2c(NC3CCCCC3)nnc(Cc3ccncc3)c2c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20100004238A1,CC(C)(C)OC(=O)NCCn1ccc2ncnc(Cl)c21.Nc1ccc(Oc2ccc(Cl)c3[nH]ncc23)c(Cl)c1>>CC(C)(C)OC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4ccc(Cl)c5[nH]ncc45)c(Cl)c3)c21,,CC(C)O,,O=C([O-])O.[Na+],,test
US20110312963A1,COc1cc([N+](=O)[O-])ccc1F.Nc1cc(O)ccn1>>COc1cc([N+](=O)[O-])ccc1Oc1ccnc(N)c1,,CC#N,CN(C)C=O,C1CCC2=NCCCN2CC1,O,test
US20040102453A1,C1CNCCN1.Cc1ccc(NC(=O)c2ccc(CCl)cc2)cc1Nc1nccc(-c2cccnc2)n1>>Cc1ccc(NC(=O)c2ccc(CN3CCNCC3)cc2)cc1Nc1nccc(-c2cccnc2)n1,,CCO,O,,,test
US20120238549A1,CN(C)C=O.CO.O=C1C=C2CCCc3cc(OS(=O)(=O)C(F)(F)F)ccc3C2(Cc2ccccc2)CC1>>COC(=O)c1ccc2c(c1)CCCC1=CC(=O)CCC12Cc1ccccc1,,CN(C)C=O,,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,,test
US20140329876A1,Cc1c(C2=NN3CC[C@@H](OC(=O)c4ccccc4)[C@H]3[C@@H]2OC2CCCCO2)ccc(C#N)c1Cl>>Cc1c(C2=NN3CC[C@@H](O)[C@H]3[C@@H]2OC2CCCCO2)ccc(C#N)c1Cl,,C1CCOC1,O,[Li]O,,test
US20150259351A1,CO.COC(=O)c1c(C)n(Cc2cncnc2)c2ccccc12>>Cc1c(C(=O)O)c2ccccc2n1C(C)C,,O,,Cl,[K+].[OH-],test
US20110105509A1,Cc1c(-c2nn(C3CC3)c(=O)c3ccccc23)c2cc(F)ccc2n1CC(=O)OC(C)(C)C>>Cc1c(-c2nn(C3CC3)c(=O)c3ccccc23)c2cc(F)ccc2n1CC(=O)O,,O=C(O)C(F)(F)F,,O,,test
US20120178946A1,CC(C)(C)[Si](C)(C)OC[C@H](O)CC#C[Si](C)(C)C>>C#CC[C@H](O)CO[Si](C)(C)C(C)(C)C,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20130102576A1,COc1ccc2c(c1)N(CC(=O)O)C(=O)C2=O.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>COc1ccc2c(c1)N(CC(=O)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC3CC3)c1)C(=O)C2=O,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20090143358A1,COC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(OC)cc2OC)c2ncc(Cl)s2)c(Cl)c1>>O=C(O)c1ccc(S(=O)(=O)Nc2ncc(Cl)s2)c(Cl)c1,,CO,,[Na+].[OH-],,test
US04548932,CCO.CCOC(=O)[C@H](CCCCCCCCN1C(=O)c2ccccc2C1=O)N[C@H]1COc2ccccc2N(CC(=O)OC(C)(C)C)C1=O>>CCOC(=O)[C@H](CCCCCCCCNC(=O)OC(C)(C)C)N[C@H]1COc2ccccc2N(CC(=O)OC(C)(C)C)C1=O,,CCO,,NN,O,test
US04824867,CC(=O)Cl.CCCCCCCCCCCC[N+](C)(C)CCO.[Br-]>>CCCCCCCCCCCC[N+](C)(C)CCOC(C)=O.[Br-],,CC(C)=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20160166575A1,Nc1cccc(C(F)(F)F)c1.O=C(O)Cc1cccc(I)c1>>O=C(Cc1cccc(I)c1)Nc1cccc(C(F)(F)F)c1,,CC(=O)N(C)C,CCOC(C)=O,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,test
US20150133446A1,COC(=O)c1cccc2oc(-c3cn4nc(SC)sc4n3)cc12>>CSc1nn2cc(-c3cc4c(C(=O)O)cccc4o3)nc2s1,,CC(=O)O,,Br,,test
US20040167131A1,CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2(NC(=O)OC(C)(C)C)CCOCC2)c(F)c1.O=C=Nc1ccc(Cl)cc1>>NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2(NC(=O)Nc3ccc(Cl)cc3)CCOCC2)c(F)c1,,C1CCOC1,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20150051208A1,CN1CCNCC1.O=[N+]([O-])c1ccc(F)cc1NCc1ccccc1>>CN1CCN(c2ccc([N+](=O)[O-])c(NCc3ccccc3)c2)CC1,,CC#N,,O,,test
US20130023541A1,COC(=O)c1cccnc1Cl>>OCc1cccnc1Cl,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140087992A1,CON(C)C(=O)c1cccc(CBr)c1[N+](=O)[O-].O>>CON(C)C(=O)c1cccc(CO)c1[N+](=O)[O-],,C1COCCO1,,O=C([O-])[O-].[Ca+2],,test
US20160200704A1,Cc1nc(N(C)C)ccc1CN.O=C(O)c1ccnc(Cc2ccc3ncc(Cl)cc3c2)c1>>Cc1nc(N(C)C)ccc1CNC(=O)c1ccnc(Cc2ccc3ncc(Cl)cc3c2)c1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US07148218B2,C=C/C=C\[C@H](C)[C@H](OC(N)=O)[C@@H](C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)C(=O)N(C)C[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)/C=C\C(=O)OC>>C=C/C=C\[C@H](C)[C@H](OC(N)=O)[C@@H](C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)C(=O)N(C)C[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)/C=C\CO,,ClCCl,,CC(C)C[Al+]CC(C)C.[H-],,test
US20010027196A1,CS(=O)c1nc(N)nc(-c2ccco2)c1Cl.OCCCc1ccccc1>>Nc1nc(OCCCc2ccccc2)c(Cl)c(-c2ccco2)n1,,C1COCCO1,,C1CCC2=NCCCN2CC1,,test
US20030004172A1,Cn1c(=O)n(Cc2ccc(C(=O)OC(C)(C)C)cc2)c(=O)c2cc(C(=O)OCc3ccccc3)sc21>>Cn1c(=O)n(Cc2ccc(C(=O)OC(C)(C)C)cc2)c(=O)c2cc(C(=O)O)sc21,,C1CCOC1,O,[Li+].[OH-],,test
US20080119518A1,COc1ccc(C2CCN(C)CC2)cc1CC1COC(C)(C)O1.Cl>>COc1ccc(C2CCN(C)CC2)cc1CC(O)CO.Cl,,CO,,CCOC(C)=O,,test
US07312225B2,NS(=O)(=O)c1ccc([N+](=O)[O-])cc1OCCCCNc1nc(Cl)ncc1Br>>Nc1ccc(S(N)(=O)=O)c(OCCCCNc2nc(Cl)ncc2Br)c1,,C1CCOC1,Cl,[Na+].[OH-],,test
US20100256143A1,BrC(Br)(Br)Br.OCc1nc(Cl)cc(N2CCOCC2)n1>>Clc1cc(N2CCOCC2)nc(CBr)n1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US08506655B1,O=[N+]([O-])c1cccc(P(=O)(O)c2cccc([N+](=O)[O-])c2)c1>>Nc1cccc(P(=O)(O)c2cccc(N)c2)c1,[Pt],CO,,[H][H],,test
US20130090340A1,COC(=O)/C=C/c1cccc(C#N)c1.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>COC(=O)c1c[nH]cc1-c1cccc(C#N)c1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20110152080A1,CCN(C)C(OC)OC.Cc1cc(N)c(Cl)cc1Oc1nc(C2(Cl)CC2)ns1>>CCN(C)C=Nc1cc(C)c(Oc2nc(C3(Cl)CC3)ns2)cc1Cl,,Cc1ccccc1,,,,test
US20070203118A1,CCOC(=O)C1c2c(F)ccc(C)c2C=CN1C(C)=O>>CCOC(=O)C1c2c(F)ccc(C)c2CCN1C(C)=O,[Pd],CCO,,,,test
US20040058820A1,CC(=O)C(CC(C)C)c1ccccc1>>CC(C)CC(c1ccccc1)C(C)O,,CO,,[BH4-].[Na+],,test
US20020156296A1,CC(C)(C)c1cc2occc2cc1O>>CC(C)(C)c1cc2c(cc1O)CCO2,[Pd],CC(=O)O,,,,test
US04746352,CC(C)OC(=O)c1cc(NC(N)=O)c(F)cc1Br.CCOC(=O)C1CCCC1=O>>CCOC(=O)C1=C(NC(=O)Nc2cc(C(=O)OC(C)C)c(Br)cc2F)CCC1,,Cc1ccccc1,,,,test
US20040092533A1,CC[Si](CC)(CC)OC(C)(C)c1ccn2c(-c3cccc(-c4ccccc4C#N)n3)cnc2n1>>CC(C)(O)c1ccn2c(-c3cccc(-c4ccccc4C#N)n3)cnc2n1,Cl,CCO,,,,test
US20020006928A1,CS(=O)(=O)n1c(-c2ccc(OCCCN3CCCCC3)cc2)cc2ccccc21>>c1ccc2[nH]c(-c3ccc(OCCCN4CCCCC4)cc3)cc2c1,,CO,,[K+].[OH-],,test
US07259262B2,COc1ccc(-c2nc(Cn3ccnn3)cs2)cc1>>Oc1ccc(-c2nc(Cn3ccnn3)cs2)cc1,,Br,,N,,test
US05071999,C=CC(C)N(CC=O)C(=O)OCC.O=C(O)CNCc1ccccc1>>CCOC(=O)N1CC2C(CCN2Cc2ccccc2)C1C,,Cc1ccccc1,,O,,test
US20070010542A1,COC1OCC(CO)CO1.Cc1c(Cl)cc[n+]([O-])c1C>>COC1OCC(COc2cc[n+]([O-])c(C)c2C)CO1,,CS(C)=O,,[H-].[Na+],,test
US20160002188A1,O=C(OCc1ccccc1)N1CCN(C(=O)c2ccc(-c3nc4ccc(F)cc4o3)cc2)C2(CC2)C1>>O=C(c1ccc(-c2nc3ccc(F)cc3o2)cc1)N1CCNCC12CC2,[Pd],CO,,,,test
US06013649,CS(=O)(=O)Cl.O=C(NCCN1CCOCC1)C(O)CCS(=O)(=O)Cc1cccc(Oc2ccccc2)c1>>CS(=O)(=O)OC(CCS(=O)(=O)Cc1cccc(Oc2ccccc2)c1)C(=O)NCCN1CCOCC1,,ClCCl,,CCN(CC)CC,,test
US06110937,Cc1cc(-c2cccc([N+](=O)[O-])c2)cc(C)c1OCC1CCCN(C)C1>>Cc1cc(-c2cccc(N)c2)cc(C)c1OCC1CCCN(C)C1,O=[Pt],CCOC(C)=O,,CCO,[H][H],test
US20150167048A1,O=C(Cc1ccccc1)N[C@@H]1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(COc3ccc4ccc(=O)oc4c3)CS[C@H]12>>O=C(Cc1ccccc1)N[C@@H]1C(=O)N2C(C(=O)O)=C(COc3ccc4ccc(=O)oc4c3)CS[C@H]12,,O,,ClCCl,O=C(O)C(F)(F)F,test
US20070060607A1,O=C(O)c1cccc(O)c1.c1ccccc1>>CC(C)(C)OC(=O)c1cccc(O)c1,,c1ccccc1,,,,test
US20160002175A1,Cc1cccc(B(O)O)c1C.Nc1nc(Cl)c2c(n1)NCCC2>>Cc1cccc(-c2nc(N)nc3c2CCCN3)c1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150031685A1,CCN(CC)C(=O)COc1cccc([C@@H](CN2CC[C@H](O)C2)NC)c1.O=C(O)Cc1ccc2c(c1)NC(=O)C2>>CCN(CC)C(=O)COc1cccc([C@@H](CN2CC[C@H](O)C2)N(C)C(=O)Cc2ccc3c(c2)NC(=O)C3)c1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20100280268A1,COC(=O)c1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(OC)c2)ccc1NS(=O)(=O)c1ccc(C)cc1>>COc1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C(=O)O)c2)ccc1NS(=O)(=O)c1ccc(C)cc1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20080194647A1,CCOC(=O)c1cncc(C#Cc2ccccc2)c1>>OCc1cncc(/C=C/c2ccccc2)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080027041A1,CCOC(=O)c1noc(C)c1C(=O)c1ccc(OC)cc1.NN>>COc1ccc(-c2n[nH]c(=O)c3noc(C)c23)cc1,,CCO,,O,,test
US20010051631A1,CC(C)(CCO)CCC12C=CC=CC1C(=O)NC2=O.CS(=O)(=O)Cl>>CC(C)(CCOS(C)(=O)=O)CCC12C=CC=CC1C(=O)NC2=O,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US06093732,NCc1ccc(Cl)cc1.O=C(O)c1cnc2cc(Cl)ccc2c1O>>O=C(NCc1ccc(Cl)cc1)c1cnc2cc(Cl)ccc2c1O,,CN(C)C=O,,O,O=C(n1ccnc1)n1ccnc1,test
US20100016319A1,CCN(CC)C(=O)C1CCCNC1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(F)ccc2Oc2ccnc(Cl)n2)cc1>>CCN(CC)C(=O)C1CCCN(c2nccc(Oc3ccc(F)cc3CNC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)n2)C1,,CCO,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US04471117,CCc1cc2c(cc1[N+](=O)[O-])N1CCCN=C1S2>>CCc1cc2c(cc1N)N1CCCN=C1S2,[Pt],CC(=O)O,,[H][H],,test
US20130131039A1,COC(=O)/C=C/CC(=O)OC.Cn1cc(-c2cc3nccn3c(-c3cn[nH]c3)n2)cn1>>COC(=O)CC(CC(=O)OC)n1cc(-c2nc(-c3cnn(C)c3)cc3nccn23)cn1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20100197723A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.[Li]CCCC>>CCCCC1(O)CCN(C(=O)OC(C)(C)C)CC1,,CCOCC,,,,test
US20110105514A1,CCCCOC(=O)CCc1ccc(OC(F)F)c(F)c1>>O=C(O)CCc1ccc(OC(F)F)c(F)c1,,CO,,O,[Na+].[OH-],test
US20140039132A1,COc1ccc(OC)cc1.II>>COc1ccc(OC)c(I)c1,,CC#N,,,,test
US20070293516A1,CC(C)n1nc(I)c2c(N)ncnc21.CC1(C)OB(c2ccc(S(N)(=O)=O)cc2)OC1(C)C>>CC(C)n1nc(-c2ccc(S(N)(=O)=O)cc2)c2c(N)ncnc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US20060041023A1,CC(C)(C)OC(=O)NCCSc1c([N+](=O)[O-])cc(C(C)(C)C)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)NCCSc1c(N)cc(C(C)(C)C)cc1N,,CCO,,CC(=O)[O-].[Na+],,test
US20050143381A1,C1CCC2OC2C1.O=c1[nH]nc2c(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)cnn12>>O=c1n(C2CCCCC2O)nc2c(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)cnn12,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04053596,BrCCCC1=CCc2ccccc21.C1CCNCC1>>C1=C(CCCN2CCCCC2)c2ccccc2C1,,Cc1ccccc1,,,,test
US05108485,C=[N+]=[N-].Cc1nc2c(C3=NC(C)(C(C)C)C(=O)N3)c(C(=O)O)ccc2n1C>>COC(=O)c1ccc2c(nc(C)n2C)c1C1=NC(C)(C(C)C)C(=O)N1,,CCOCC,CO,CC(=O)O,,test
US20100197651A1,COc1cn(-c2ccc(I)cc2F)nc(-c2ccnn2-c2ccccc2)c1=O.O=C1CCCN1>>COc1cn(-c2ccc(N3CCCC3=O)cc2F)nc(-c2ccnn2-c2ccccc2)c1=O,[Cu]I,C1COCCO1,O,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US04275077,O=[N+]([O-])c1ccc(Cl)c(Cl)c1.Oc1cccc2ccccc12>>O=[N+]([O-])c1ccc(Oc2cccc3ccccc23)c(Cl)c1,[Cu],Cc1ccccc1C,,O,[K+].[OH-],test
US20060287324A1,Clc1ccc(-c2cc(Cl)ncc2Br)cc1.NN>>NNc1cc(-c2ccc(Cl)cc2)c(Br)cn1,,C1CCOC1,,,,test
US20080269305A1,CC(C)(C)OC(=O)c1ccccc1-c1ccc(CBr)c(F)c1.CCOc1nc(Cl)c(C=O)[nH]1>>CCOc1nc(Cl)c(C=O)n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030022886A1,CCI.COc1cc(I)cc(OC)c1O>>CCOc1c(OC)cc(I)cc1OC,,CN(C)C=O,,Cl,[H-].[Na+],test
US20140023642A1,Cc1cccc(C(=O)NC(C)(C)C)c1N.O=C(n1ccnc1)n1ccnc1>>Cc1cccc2c(=O)n(C(C)(C)C)c(=O)[nH]c12,,C1CCOC1,,,,test
US20130217762A1,C1CC2OC2CO1.[N-]=[N+]=[N-]>>[N-]=[N+]=N[C@@H]1CCOC[C@H]1O,,CO,O,[Cl-].[NH4+],,test
US20060122268A1,Brc1ccc(I)cc1.OB(O)c1ccncc1>>Brc1ccc(-c2ccncc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20150031690A1,FS(F)(F)N1CCOCC1.OCC1=NOC(C(F)(F)F)C1>>FCC1=NOC(C(F)(F)F)C1,,ClCCl,,O=C([O-])O.[Na+],,test
US20150119405A1,COc1cc(OC)c(Cl)c(-c2ccc3nc(N[C@@H]4[C@H]5C[C@H]5C[C@@H]4NC(=O)OCC[Si](C)(C)C)ncc3c2)c1Cl>>COc1cc(OC)c(Cl)c(-c2ccc3nc(N[C@@H]4[C@H]5C[C@H]5C[C@@H]4N)ncc3c2)c1Cl,,C1COCCO1,,Cl,,test
US06075029,Cc1nc2c(c(=O)n(CCCC[C@@H](C)O)c(=O)n2C)n1Cc1ccccc1>>Cc1nc2c([nH]1)c(=O)n(CCCC[C@@H](C)O)c(=O)n2C,[Pd],CC(=O)O,CCOC(C)=O,,,test
US20080146562A1,Cc1nc2cc(N3CCOCC3)c(F)cc2c(=O)[nH]1.OCCN1CCOCC1>>Cc1nc2cc(OCCN3CCOCC3)c(F)cc2c(=O)[nH]1,,CN(C)C=O,,[H-].[Na+],,test
US20150376130A1,CCCCNc1ncccc1C(=O)OCC>>CCCCNc1ncccc1C(=O)O,,C1CCOC1,,[Na+].[OH-],,test
US20150183801A1,O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(Br)c1.OB(O)c1cncc(C(F)(F)F)c1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2cncc(C(F)(F)F)c2)c1,,C1COCCO1,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20150191463A1,Cc1cccc(N)c1C(=O)O.Cl.[I-]>>Cc1cccc(I)c1CCl,,O,,O=N[O-].[Na+],,test
US20110053916A1,CC(C)(C)NS(=O)(=O)c1ccc(-c2nc(O)cc(C3CC3)n2)s1.O=C1CCC(=O)N1Cl>>CC(C)(C)NS(=O)(=O)c1ccc(-c2nc(O)c(Cl)c(C3CC3)n2)s1,,CC(=O)O,,,,test
US04474754,Cc1ccc(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)OCc2ccccc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)O)cc1>>Cc1ccc(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)O)cc1,[Pd],CO,,CC(=O)O,,test
US20050004157A1,CC(=O)OC(CBr)Cc1c(O)ccc2ncccc12>>CC(=O)OC1COc2ccc3ncccc3c2C1,,CN(C)C=O,,[H-].[Na+],,test
US07442833B2,CC/C(=C(/c1ccc(O)cc1)c1ccc(/C=C/C(=O)OC(C)(C)C)cc1)c1ccccc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC/C(=C(\c1ccc(/C=C/C(=O)OC(C)(C)C)cc1)c1ccc(OC(=O)Oc2ccc([N+](=O)[O-])cc2)cc1)c1ccccc1,,ClCCl,,c1ccncc1,,test
US05071871,CC1(C)Oc2ccc(C#N)cc2C2OC21.O=C1CCC(=O)C1>>CC1(C)Oc2ccc(C#N)cc2[C@@H](OC2=CC(=O)CC2)[C@@H]1O,[Cu]Br,C1CCOC1,,[H-].[Na+],,test
US20150141406A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=C1COCCN1c1ccc(Br)cc1>>CC1(C)OB(c2ccc(N3CCOCC3=O)cc2)OC1(C)C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CS(C)=O,,CC(=O)[O-].[K+],,test
US20070219187A1,C#CC1CCCN(C(=O)OC(C)(C)C)C1.Fc1ccc(I)cc1>>CC(C)(C)OC(=O)N1CCCC(C#Cc2ccc(F)cc2)C1,[Cu]I,CCN(CC)CC,,,,test
US05602149,CCC(=O)N(C(=O)CC)c1c(-c2cccs2)cccc1S(=O)(=O)O.ClP(Cl)(Cl)(Cl)Cl>>CCC(=O)N(C(=O)CC)c1c(-c2cccs2)cccc1S(=O)(=O)Cl,,ClCCl,,CCN(CC)CC,CCOCC,test
US20160176871A1,NCCN1CCOCC1.O=C(CCl)Nc1cc(-c2[nH]c3cc(Cl)cnc3c2-c2ccc(F)cn2)ccn1>>O=C(CNCCN1CCOCC1)Nc1cc(-c2[nH]c3cc(Cl)cnc3c2-c2ccc(F)cn2)ccn1,,CC#N,O,O=C(O)C(F)(F)F,,test
US20060235037A1,CC(C)(C)OC(=O)N1CCC(=O)C1.COc1ccccc1-c1cc2cc(C3CCNCC3)ccc2[nH]1>>COc1ccccc1-c1cc2cc(C3CCN(C4CCNC4)CC3)ccc2[nH]1,,ClCCl,,CC(=O)O,[Na],test
US20120022058A1,NCc1cc(Br)ccc1N.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=C1NCc2cc(Br)ccc2N1,,C1CCOC1,O,CCN(CC)CC,[Na+].[OH-],test
US04294760,COC(=O)Cc1ccc(C(O)(C#N)c2ccccc2)n1C>>Cn1c(CC(=O)O)ccc1C(=O)c1ccccc1,,[Na+],[OH-],Cl,,test
US20100227859A1,COC(=O)[C@@H](NS(=O)(=O)c1ccc2c(c1)oc1ccc(C(=N)NC(C)C)cc12)C(C)C>>CC(C)NC(=N)c1ccc2oc3cc(S(=O)(=O)N[C@H](C(=O)O)C(C)C)ccc3c2c1,,CC(=O)O,,Cl,,test
US20020103211A1,CC(=O)O[C@H](C)CCCCn1c(=O)c2c(nc3n2CCCN3)n(C)c1=O>>C[C@@H](O)CCCCn1c(=O)c2c(nc3n2CCCN3)n(C)c1=O,,CO,,CCOCC,Cl,test
US20140213586A1,COc1cccc(N)c1.O=Cc1ccccc1>>COc1cccc(N=Cc2ccccc2)c1,,CCO,,O=S(=O)([O-])[O-].[Mg+2],,test
US05811389,COc1ccc2c(c1CN)Oc1c(ccc(OC)c1CC(=O)OCc1ccccc1)C2(C)C.O=C(O)C(F)(F)F>>COc1ccc2c(c1CN)Oc1c(ccc(OC)c1CC(=O)O)C2(C)C.O=C(O)C(F)(F)F,[Pd],CO,,,,test
US20160222015A1,CC(C)(C)OC(=O)N1CC2CC(O)C2C1.CC(C)OP(=O)(Cl)OC(C)C>>CC(C)OP(=O)(OC(C)C)OC1CC2CN(C(=O)OC(C)(C)C)CC21,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20090054435A1,CCOC(=O)CBr.COc1ccc(C(=O)c2cccc(OCc3nc(-c4ccccc4)oc3C)c2)c(O)c1>>COc1ccc(C(=O)c2cccc(OCc3nc(-c4ccccc4)oc3C)c2)c(OCCOC(C)=O)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05026856,CC(C)(C)OC(=O)NCc1cccc2c1CN(C(=O)OCc1ccccc1)C2>>CC(C)(C)OC(=O)NCc1cccc2c1CNC2,[Pd],CO,,,,test
US20100292238A1,COc1ccc(C2=C(c3ccc(OCc4nc5ccccn5c4Cl)cc3)C(=O)C(C)(C)O2)cc1.CS(=O)(=O)O>>COc1ccc(C2=CC(=O)C(C)(C)O2)cc1.CS(=O)(=O)O,,CCOCC,ClCCl,,,test
US04016166,C#CCNC(=O)c1ccccc1Nc1cccc([N+](=O)[O-])c1.O=C(n1ccnc1)C(Cl)(Cl)Cl>>C#CCn1c(=O)c2ccccc2n(-c2cccc([N+](=O)[O-])c2)c1=O,,O,,C1CCOC1,[H-].[Na+],test
US20140315888A1,CNC1CN(c2nc3ncc(Br)cc3n3nnnc23)C1.Cl>>CNC1CN(c2nc3ncc(Br)cc3n3nnnc23)C1.Cl,,CCOCC,,C1COCCO1,,test
US20020006936A1,NOCC(=O)O.O=C1CCCc2cc(OCCn3ccnc3)ccc21>>O=C(O)CON=C1CCCc2cc(OCCn3ccnc3)ccc21,,O,c1ccncc1,Cl,,test
US20120157430A1,Brc1ncnc2[nH]cnc12.Cc1c(Cl)cc(C(C)N)c(-c2cccc(F)c2)c1N1CCOC1=O>>Cc1c(Cl)cc(C(C)Nc2ncnc3[nH]cnc23)c(-c2cccc(F)c2)c1N1CCOC1=O,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20020052512A1,CCOC(C)=O.Cc1cc(C(=O)NCc2cccc(O[Si](C)(C)C(C)(C)C)c2)cc(Cl)c1C(=O)N[C@@H](CNC(=O)c1cccs1)C(=O)O>>COC(=O)[C@H](CNC(=O)c1cccs1)NC(=O)c1c(C)cc(C(=O)NCc2cccc(O)c2)cc1Cl,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150344408A1,CN(CC[C@@H](Oc1ccc(CCO)cc1)c1ccccc1)C(=O)OC(C)(C)C>>CNCC[C@@H](Oc1ccc(CCO)cc1)c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040116424A1,CCCCn1c(-c2ccccc2C)nc(Cl)c1CN(CCC(C)C)Cc1ccc2[nH]ccc2c1.O=C1CCC(=O)N1Cl>>CCCCn1c(-c2ccccc2C)nc(Cl)c1CN(CCC(C)C)Cc1ccc2[nH]cc(Cl)c2c1,,CC#N,,,,test
US20130053346A1,CC(C)(C)OC(=O)N1CCN(Cc2ccc(N)cc2)CC1.CCOC(=O)c1c(C)nc(Cl)nc1Cl>>CCOC(=O)c1c(C)nc(Cl)nc1Nc1ccc(CN2CCN(C(=O)OC(C)(C)C)CC2)cc1,,CN1CCCC1=O,,,,test
US20040167127A1,CCCBr.COc1ccc(-c2n[nH]c3c(Cl)cccc23)cc1Cl>>CCCn1nc(-c2ccc(OC)c(Cl)c2)c2cccc(Cl)c21,,CN(C)C=O,,[H-].[Na+],,test
US20120172333A1,CCOC(=O)c1ccc(-n2ccc(N)c2C(=O)OCC)cc1.N#CCC(=O)O>>CCOC(=O)c1ccc(-n2ccc(NC(=O)CC#N)c2C(=O)OCC)cc1,,CC#N,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20050288314A1,CC(O)c1ccc(F)cc1.N#Cc1c(F)cccc1F>>CC(Oc1cccc(F)c1C#N)c1ccc(F)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20120316147A1,COC(=O)c1ccc2c(n1)CC(C)(C)CC2>>CC1(C)CCc2ccc(C(=O)O)nc2C1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US05364943,COc1ccc(OC(F)(F)F)cc1CNc1cccnc1-c1ccccc1.Cl>>COc1ccc(OC(F)(F)F)cc1CN[C@H]1CCCN[C@H]1c1ccccc1.Cl,[Pt],,,CO,[H][H],test
US20100120763A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cc1ncccc1Br>>Cc1ncccc1B1OC(C)(C)C(C)(C)O1,,CN(C)C=O,,CC(=O)[O-].[K+],,test
US20060148842A1,CC1=CNC(=O)C2C(C)CCC12.CCCCI>>CCCCN1C=C(C)[C@H]2CC[C@H](C)[C@H]2C1=O,,C1CCOC1,,,,test
US05436350,CC[C@@H]1C(=O)OC[C@@H]1Cc1cncn1C.[Na+].[OH-]>>CC[C@@H](C(=O)[O-])[C@H](CO)Cc1cncn1C.[Na+],,O,,Cl,Cl,test
US20010051657A1,COC(=O)CC(=O)Nc1cc(C)c(Oc2ccc(O)c(C(=O)c3ccc(F)cc3)c2)c(C)c1>>COC(=O)CC(=O)Nc1cc(C)c(Oc2ccc(O)c(C(O)c3ccc(F)cc3)c2)c(C)c1,[Ni],CCO,CCOC(C)=O,,,test
US20080070912A1,CC(C)C(=O)c1c(-c2ccc(Cl)cc2)nn2ccccc12.NO>>CC(C)C(=NO)c1c(-c2ccc(Cl)cc2)nn2ccccc12,,CCO,O,Cl,[Na+].[OH-],test
US20050009843A1,C1CCNC1.CC(C)(C)OC(=O)/C=C/c1c(N2CCC[C@@H](OC(=O)NCCCl)C2)nc2cc(C(=O)Nc3nc(C(C)(C)C)cs3)ccn2c1=O>>CC(C)(C)OC(=O)/C=C/c1c(N2CCC[C@@H](OC(=O)NCCN3CCCC3)C2)nc2cc(C(=O)Nc3nc(C(C)(C)C)cs3)ccn2c1=O,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20020035065A1,CC1(C)OC(=O)[C@H](CCO)O1.CS(=O)(=O)Cl>>CC1(C)OC(=O)[C@H](CCOS(C)(=O)=O)O1,,ClCCl,,CCN(CC)CC,,test
US20130102576A1,COC(=O)CN1C(=O)C2(OCC(C)(C)CO2)c2cc(N)ccc21.CS(=O)(=O)Cl>>COC(=O)CN1C(=O)C2(OCC(C)(C)CO2)c2cc(NS(C)(=O)=O)ccc21,,c1ccncc1,,,,test
US20020193367A1,CCCN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3nncc3COC3CCCCO3)c2)cc1C(F)(F)F>>CCCN(C)c1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-n3nncc3CO)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US04922021,CCN(CC(C)Nc1c(C)cccc1C)C(C)=O>>CCN(CC)CC(C)Nc1c(C)cccc1C,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150119373A1,CC(C)(C)OC(=O)N[C@@H]1C[C@H](C(=O)O)C1(C)C>>CC1(C)[C@H](N)C[C@@H]1C(=O)O,,Cc1ccccc1,ClCCl,O=C(O)C(F)(F)F,,test
US20120082702A1,COC(=O)c1ccc(Nc2nc(Cl)ccc2C(N)=O)cc1>>NC(=O)c1ccc(Cl)nc1Nc1ccc(C(=O)O)cc1,,CO,,Cl,[Na+].[OH-],test
US05576343,CC(C)(C)OC(=O)N1CC[C@@H](O)C1.COc1cc(C=O)ccc1O>>COc1cc(C=O)ccc1O[C@H]1CCN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100130739A1,Cc1nc(OCC(=O)N(C)C2CCN(Cc3ccccc3)CC2)nc(C)c1N.Cl>>Cc1nc(OCC(=O)N(C)C2CCN(Cc3ccccc3)CC2)nc(C)c1N.Cl,,CO,,C1COCCO1,,test
US20100173968A1,CC(C)(C)OC(=O)N1CC2C=C(C(=O)c3ccco3)CC2C1.O=C(O)C(F)(F)F>>O=C(C1=CC2CNCC2C1)c1ccco1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US04166852,CC(=O)OC(C)=O.CC1C(=O)N=C(N)NC1=O>>CC(=O)NC1=NC(=O)C(C)C(=O)N1,,CC(=O)O,,,,test
US20070105836A1,CI.O=C(c1cccnc1)N1CCN(C2=Nc3cc(Cl)ccc3Nc3ccccc32)CC1>>CN1C=CC=C(C(=O)N2CCN(C3=Nc4cc(Cl)ccc4Nc4ccccc43)CC2)C1.[I-],,CO,,,,test
US05696138,COc1ccc(C(F)(F)F)cc1N.O=C=Nc1cc(Cl)cc(Cl)c1>>COc1ccc(C(F)(F)F)cc1NC(=O)Nc1cc(Cl)cc(Cl)c1,,Cc1ccccc1,,,,test
US20130210796A1,CC(=O)OCC(=O)Nc1cc(C#N)cc(C(F)(F)F)c1.C[Si](C)(C)N=[N+]=[N-]>>CC(=O)OCc1nnnn1-c1cc(C#N)cc(C(F)(F)F)c1,,C1CCOC1,CCOC(C)=O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140288123A1,BrC(Br)(Br)Br.O=Cc1ccccc1O>>Oc1ccccc1C=C(Br)Br,,ClCCl,O,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090247559A1,NC(=O)c1oc2ccc(Br)cc2c1NC(=O)c1ccncc1Cl>>O=c1[nH]c(-c2ccncc2Cl)nc2c1oc1ccc(Br)cc12,,CCO,O,Cl,[Na+].[OH-],test
US20140179666A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cc(C)c(N)cn1>>COc1cc(C)c(NC(=O)OC(C)(C)C)cn1,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20050148627A1,CCOC(=O)C1=Cc2cc(Cl)c(CBr)cc2OC1C(F)(F)F.Oc1ccccc1>>CCOC(=O)C1=Cc2cc(Cl)c(COc3ccccc3)cc2OC1C(F)(F)F,,CN(C)C=O,,[H-].[Na+],,test
US20160039842A1,C1COCCN1.COc1cc2c(cc1-c1c(C)noc1C)nc(C=O)c1oc(=O)n(Cc3ccccc3)c12>>COc1cc2c(cc1-c1c(C)noc1C)nc(CN1CCOCC1)c1oc(=O)n(Cc3ccccc3)c12,,ClCCCl,,O=C([O-])O.[Na+],,test
US20140275087A1,CO.Cn1cnc(S(=O)(=O)N2C[C@@H](NCc3cc(C(F)(F)F)ccc3N)[C@H](c3ccccc3)C2)c1>>Cn1cnc(S(=O)(=O)N2C[C@@H](c3ccccc3)[C@H](N3Cc4cc(C(F)(F)F)ccc4NC3=O)C2)c1,,ClCCl,,CCN(CC)CC,,test
US20140094473A1,CCOC(=O)CC(Nc1nc(-c2cn(S(=O)(=O)c3ccc(C)cc3)c3ncc(F)cc23)ncc1F)C1(C)CCCCC1>>CCOC(=O)CC(Nc1nc(-c2c[nH]c3ncc(F)cc23)ncc1F)C1(C)CCCCC1,,CC#N,,Cl,,test
US20060084676A1,COC(=O)c1c(Cl)cc(Cl)cc1NC(=O)C(C)c1ccc([N+](=O)[O-])cc1>>CC1(c2ccc([N+](=O)[O-])cc2)C(=O)Nc2cc(Cl)cc(Cl)c2C1=O,,C1CCOC1,,[H-].[Na+],,test
US20090318503A1,BrCCCCCCCCCCCBr.Cc1cccnc1>>BrCCCCCCCCCCCCc1cccnc1,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US06573270B1,Cc1ccc(-c2c(OCCO)nn(C)c2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)cc1.O=[N+]([O-])c1cnc(Cl)nc1>>Cc1ccc(-c2c(OCCOc3ncc([N+](=O)[O-])cn3)nn(C)c2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)cc1,,C1CCOC1,CC(=O)N(C)C,[H-].[Na+],,test
US20040053973A1,Cc1cccc(C(=O)C(Br)c2ccnc(N)c2)c1.NC(=S)c1ccccc1Cl>>Cc1cccc(-c2nc(-c3ccccc3Cl)sc2-c2ccnc(N)c2)c1,,CN(C)C=O,,Br,O=C([O-])O.[Na+],test
US05840732,CCOC(=O)C(C)C(=O)OCC.NC(=O)NCc1ccccc1>>CC1C(=O)NC(=O)N(Cc2ccccc2)C1=O,,CO,,C[O-].[Na+],,test
US20110065764A1,CCOC(=O)c1cc(-c2ccc(C(F)(F)F)c(F)c2)on1>>OCc1cc(-c2ccc(C(F)(F)F)c(F)c2)on1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120225854A1,CC#CC1CNCCN1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1.O=S(=O)(Cl)c1ccccc1>>CC#C[C@H]1CN(S(=O)(=O)c2ccccc2)CCN1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1,,ClCCl,,CCN(CC)CC,,test
US06002008,COc1ccc2ncc(C#N)c(Cl)c2c1.Nc1ccc(Cl)cc1F>>COc1ccc2ncc(C#N)c(Nc3ccc(Cl)cc3F)c2c1,,CCOCCO,,Cl,c1ccncc1,test
US20160218303A1,COS(=O)(=O)C(F)(F)F.Cc1cc(C)cc(-n2cnc3c(C#N)cccc32)c1>>Cc1cc(C)cc(-n2c[n+](C)c3c(C#N)cccc32)c1.O=S(=O)([O-])C(F)(F)F,,ClCCl,,,,test
US05280026,CN(c1ccccc1)c1nc(Cl)nc2sccc12.Cc1cc(F)ccc1N>>Cc1cc(F)ccc1Nc1nc(N(C)c2ccccc2)c2ccsc2n1.Cl,,CO,,,,test
US20160185780A1,CC(C)(C)OC(=O)N1CCC(CO)(c2ccc(C(F)F)cc2)CC1>>OCC1(c2ccc(C(F)F)cc2)CCNCC1,,C1COCCO1,,Cl,,test
US20050222206A1,CN1CCC(C(=O)c2cccc(NC(=O)c3c(F)cc(F)cc3F)n2)CC1>>O=C(Nc1cccc(C(=O)C2CCNCC2)n1)c1c(F)cc(F)cc1F,,CC(Cl)Cl,,CC(Cl)OC(=O)Cl,,test
US20090131458A1,COc1nc2c(N)nc(OCC3CCCO3)nc2n1C1CCCCO1.O=C(O)C(F)(F)F>>COc1nc2c(N)nc(OCC3CCCO3)nc2[nH]1.O=C(O)C(F)(F)F,,CO,,,,test
US20090143414A1,Clc1ncnc2ccc(I)cc12.Nc1ccc(OCc2cccc(F)c2)c(Cl)c1>>Cl.Fc1cccc(COc2ccc(Nc3ncnc4ccc(I)cc34)cc2)c1,,C1CCOC1,,,,test
US20130345194A1,COc1ccc(C=O)cc1.NS(=O)(=O)N1CCN(c2ncnc3[nH]ccc23)CC12CC2>>COc1ccc(/C=N\S(=O)(=O)N2CCN(c3ncnc4[nH]ccc34)CC23CC3)cc1,,Cc1ccccc1,,,,test
US20060235029A1,CSc1nc(-c2cc(C(=O)Nc3nccs3)ccc2C)c2ccc(=O)n(-c3c(F)cccc3F)c2n1.O=C(OO)c1cccc(Cl)c1>>Cc1ccc(C(=O)Nc2nccs2)cc1-c1nc(S(C)=O)nc2c1ccc(=O)n2-c1c(F)cccc1F,,ClCCl,,CCCCCC,CCOC(C)=O,test
US20030229094A1,O=C(CCl)Nc1ccc(OC(F)(F)F)cc1.c1ccc(N2CCNCC2)nc1>>O=C(CN1CCN(c2ccccn2)CC1)Nc1ccc(OC(F)(F)F)cc1,,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20010018437A1,CN1CCS/C(=C\c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C1=O.O=C(OO)c1cccc(Cl)c1>>CN1CCS(=O)/C(=C\c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C1=O,,ClCCl,,,,test
US20060293340A1,Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1Nc1nccc(-c2ccc(Cl)nc2)n1.OC1CCNCC1>>Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1Nc1nccc(-c2ccc(N3CCC(O)CC3)nc2)n1,,O,,,,test
US20110118260A1,COc1cc(OC(=O)CNC(=O)OC(C)(C)C)ccc1-c1ccc2c(c1COc1cc(F)ccc1C)C(C)=CC(C)(C)N2.Cl>>COc1cc(OC(=O)CN)ccc1-c1ccc2c(c1COc1cc(F)ccc1C)C(C)=CC(C)(C)N2.Cl,,C1COCCO1,,,,test
US20150284381A1,CCOC(=O)c1cc2c(cc1Br)C(O)(c1ncc(-c3cc(C)cc(Nc4cc(C(F)(F)F)ccn4)n3)s1)CCC2>>Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnc(C3(O)CCCc4cc(C(=O)O)c(Br)cc43)s2)c1,,CO,,[Na+].[OH-],,test
US05256783,CC(C)(C)NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)OCc1ccccc1>>CC(C)(C)NC(=O)[C@@H]1Cc2ccccc2CN1,[Pd],CCO,,[H][H],,test
US20140336198A1,CC(C)(C)OC(=O)N1CC(/C(=N\O)c2ccc(F)cc2)C1>>CC(C)(C)OC(=O)N1CC(C(N)c2ccc(F)cc2)C1,[Pd],CO,,[H][H],,test
US20160106102A1,CCSCn1nc([N+](=O)[O-])cc1C>>CCSCn1nc(N)cc1C,[Pd],CO,,[H][H],,test
US06114532,CCOC(=O)CNC(=O)CN(c1ccc2c(c1)nc(Cc1ccc(C(=N)N)cc1)n2C)S(=O)(=O)c1cccc2cccnc12.O=C(Cl)OC1CCCCC1>>CCOC(=O)CNC(=O)CN(c1ccc2c(c1)nc(Cc1ccc(C(N)=NC(=O)OC3CCCCC3)cc1)n2C)S(=O)(=O)c1cccc2cccnc12,,C1CCOC1,O,Cl,,test
US04200748,O=[N+]([O-])c1ccc2nc3c(nc2c1)OCC1CCCCN31>>Nc1ccc2nc3c(nc2c1)OCC1CCCCN31,[Pd],C1COCCO1,,[H][H],,test
US20160016948A1,CC(C)n1c(COC2CCCCO2)nc2cnc(Nc3ccnc(-c4cn(CC5CC5)nc4N)n3)cc21>>CC(C)n1c(CO)nc2cnc(Nc3ccnc(-c4cn(CC5CC5)nc4N)n3)cc21,,CCO,,O=C(O)C(F)(F)F,,test
US20130245254A1,CO[C@@H]1CC[C@H](N)CC1.O=C(CI)Nc1ncc(Br)nc1Br>>CO[C@@H]1CC[C@H](N2CC(=O)Nc3ncc(Br)nc32)CC1,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20050004114A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(-c3ccc(-c4cccc5c4oc4ccccc45)cc3)cc2)CC1C(=O)[O-]>>O=C(O)C1CN(C(=O)c2ccc(-c3ccc(-c4cccc5c4oc4ccccc45)cc3)cc2)CCN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080070893A1,COC(=O)CCCCc1cnn2c(NC3CC3)nc(Nc3cccc(N)c3)nc12>>Nc1cccc(Nc2nc(NC3CC3)n3ncc(CCCCC(=O)O)c3n2)c1,,CO,O,[Na+].[OH-],,test
US04954512,CC(C)(C)OC(=O)NC[C@H]1CC[C@H](C(=O)NC(=O)[C@@H](N)Cc2ccccc2)CC1>>N[C@@H](Cc1ccccc1)C(=O)O,,CCCCCC,,C1COCCO1,Cl,test
US20080027049A1,COc1ccc(C(=O)Cl)cc1.NC1CCc2oc3ccccc3c2C1>>COc1ccc(C(=O)Nc2ccc3oc4c(c3c2)CCCC4)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20160039775A1,COC(=O)c1ccc([N+](=O)[O-])c(F)c1.Cc1c(C)c(OCc2ccccc2)c(O)c(C)c1OCc1ccccc1>>COC(=O)c1ccc([N+](=O)[O-])c(Oc2c(C)c(OCc3ccccc3)c(C)c(C)c2OCc2ccccc2)c1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080176872A1,C[C@H](N)c1ccc(F)cc1.O=[N+]([O-])c1cc(F)c(F)cc1Nc1cc(C2CC2)[nH]n1>>C[C@H](Nc1cc(Nc2cc(C3CC3)[nH]n2)c([N+](=O)[O-])cc1F)c1ccc(F)cc1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20150038488A1,CCCC[Sn](CCCC)(CCCC)c1cnccn1.C[C@@H](Oc1cc(Br)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1>>C[C@@H](Oc1cc(-c2cnccn2)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,,,test
US20090239854A1,C=Cc1cnccc1C(F)(F)F.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>Cc1ccc2c(c1)c1c(n2CCc2cnccc2C(F)(F)F)CCN(C)C1,,CN1CCCC1=O,,[K+].[OH-],,test
US20020193599A1,C=C1CC(=O)O1.NCCCN1CCCCC1>>CC(=O)CC(=O)NCCCN1CCCCC1,,C1CCOC1,,,,test
US04898871,COCCN.COc1ccc2ccc(N3C(=O)c4ccccc4C3OCC(=O)O)nc2n1>>COCCNC(=O)COC1c2ccccc2C(=O)N1c1ccc2ccc(OC)nc2n1,,CN(C)C=O,,,,test
US20070027178A1,Cc1ccc(S)cc1.Cc1cccc([N+](=O)[O-])c1Cl>>Cc1ccc(Sc2c(C)cccc2[N+](=O)[O-])cc1,,C1CCOC1,,[H-].[Na+],,test
US20110092526A1,O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cnc(Cl)nc1Cl.c1cn[nH]c1>>O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cnc(Cl)nc1-n1cccn1,,C1CCOC1,CCOC(C)=O,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20060189596A1,CC(C)(C)OC(=O)N1CC2CCC1CC2Cc1ccc(Cl)c(Cl)c1>>Clc1ccc(CC2CC3CCC2CN3)cc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130345192A1,CC(C)(C)OC(=O)N[C@H]1CCCN(C(=O)OCc2ccccc2)C1.CCBr>>CCN(C(=O)OC(C)(C)C)[C@H]1CCCN(C(=O)OCc2ccccc2)C1,,CN(C)C=O,,O,[H-].[Na+],test
US09248117B2,CC(C)(CCS)NC(=O)OCc1ccccc1.CC(O)I>>CC(C)(CCSCCO)NC(=O)OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060063759A1,Cl[Mg]Cc1ccc(Cl)cc1Cl.O=C1c2ccccc2CCc2sccc21>>Clc1ccc(C=C2c3ccccc3CCc3sccc32)c(Cl)c1,,C1CCOC1,,,,test
US20080221108A1,COC(=O)c1ccccc1NC(=O)CC1CCN(c2nc3ccccc3[n+]([O-])n2)CC1>>COC(=O)c1ccccc1NC(=O)CC1CCN(c2nnc3ccccc3n2)CC1,[Pd],CCO,,,,test
US20150111870A1,C1CNC1.CC(C)Oc1c(Cl)nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c1Cl>>CC(C)Oc1c(N2CCC2)nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c1Cl,,CN(C)C=O,,O=C(O)C(F)(F)F,,test
US05739345,Cn1c(CO)cc2ccccc21.O=C1SC(Cc2ccc(O)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1>>Cn1c(COc2ccc(CC3SC(=O)N(C(c4ccccc4)(c4ccccc4)c4ccccc4)C3=O)cc2)cc2ccccc21,,c1ccccc1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20080275244A1,CCS(=O)(=O)O.Nc1ncccc1-c1cc(Cc2ccc(COc3ccccn3)cc2)no1>>CCS(=O)(=O)O.Nc1ncccc1-c1cc(Cc2ccc(COc3ccccn3)cc2)no1,,CO,,,,test
US20090298825A1,Nc1cccc2c(=O)n(-c3cccnc3F)ccc12.O=C(O)Cc1ccc(Cl)c(C(F)(F)F)c1>>O=C(Cc1ccc(Cl)c(C(F)(F)F)c1)Nc1cccc2c(=O)n(-c3cccnc3F)ccc12,,CN(C)C=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150210682A1,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(O)cc1CC2CC.O=C(CBr)N1CCCC1>>CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCC(=O)N3CCCC3)cc1CC2CC,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060122201A1,Nc1cc(=O)n2c(n1)SCC2.O>>Nc1cc(=O)n(CCS)c(=O)[nH]1,,O,,Cl,[Na+].[OH-],test
US05298652,CCCCCCCCCCOc1cc(OCCCCCCCCCC)cc(C(=O)C(=O)N(CC(=O)OCC)CC(=O)OCC)c1>>CCCCCCCCCCOc1cc(OCCCCCCCCCC)cc(C(=O)C(=O)N(CC(=O)O)CC(=O)O)c1,,CO,,[Na+].[OH-],,test
US20110172245A1,N#CC1(c2cccc(C(=O)O)c2)CC1.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)sc3c2)c1>>N#CC1(c2cccc(C(=O)Nc3cccc(Oc4ccc5nc(NC(=O)C6CC6)sc5c4)c3)c2)CC1,CN(C)c1ccncc1,Cc1ccccc1,c1ccncc1,O=S(Cl)Cl,,test
US20050075378A1,Cc1sc(N2CCOCC2)nc1CCOc1ccc(CCC(=O)OC(C)(C)C)c(CNC(=O)OC(C)C)c1>>Cc1sc(N2CCOCC2)nc1CCOc1ccc(CCC(=O)O)c(CNC(=O)OC(C)C)c1,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US20130065906A1,Cc1ncoc1-c1ccc(C(=O)O)cc1.O=S(Cl)Cl>>Cc1ncoc1-c1ccc(C(=O)Cl)cc1,,ClCCl,,,,test
US20090214675A1,CC(N)=CC(=O)CCC1CCC1.CC([O-])=CC#N.Cc1cc(=O)c2cccc(C=O)c2o1>>CC1=C(C#N)C(c2cccc3c(=O)cc(C)oc23)C(C(=O)CCC2CCC2)=C(C)N1,,CC(C)O,,CC(=O)O,,test
US20070010556A1,CC(C)(C)OC(=O)N1CCC[C@H](NS(=O)(=O)c2sc(Cl)cc2N)C1.O=C=NC(=O)C(Cl)(Cl)Cl>>CC(C)(C)OC(=O)N1CCC[C@H](NS(=O)(=O)c2sc(Cl)cc2NC(=O)NC(=O)C(Cl)(Cl)Cl)C1,,C1CCOC1,,,,test
US20040087438A1,BrC(Br)(Br)Br.OCC1CC2C=CC1O2>>BrCC1CC2C=CC1O2,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070179142A1,CCCCOC(=O)C1(c2ccc(-n3cccn3)cc2)CC1>>O=C(O)C1(c2ccc(-n3cccn3)cc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120309750A1,CCCC[Sn](CCCC)(CCCC)c1cc(C(=O)OCC)no1.CCNC(=O)c1noc(-c2cc(C(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)c1I>>CCNC(=O)c1noc(-c2cc(C(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)c1-c1cc(C(=O)OCC)no1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US05811428,COC(=O)c1c[nH]c(=O)c(C)n1.O=P(Cl)(Cl)Cl>>COC(=O)c1cnc(Cl)c(C)n1,,CN(C)C=O,,,,test
US20150191439A1,Brc1ccc(CNC23CC4CC(CC(C4)C2)C3)s1.II>>Ic1ccc(CNC23CC4CC(CC(C4)C2)C3)s1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20090270387A1,CCCCCC(OCc1ccc(OC)cc1)c1ccc([C@H]2C(=O)CC[C@@H]2CCCc2ccc(C(=O)OC)s2)cc1.ClC(Cl)Cl>>CCCCCC(OCc1ccc(OC)cc1)c1ccc([C@@H]2[C@@H](CCCc3ccc(C(=O)OC)s3)CCC2(Cl)Cl)cc1,,CO,,CCN(CC)CC,,test
US20060276536A1,COCOc1ccc(C=CC(C)=O)cc1OC.O=Cc1ccccc1>>COc1cc(C=CC(=O)C=Cc2ccccc2)ccc1O,,CCO,,O,[Na+].[OH-],test
US20140155419A1,Cc1ccnc(C)c1CO.O=S(Cl)Cl>>Cc1ccnc(C)c1CCl,,ClCCl,,,,test
US20160257668A1,COC(=O)C1NCC(C2CCN(C(=O)OC(C)(C)C)CC2)CC1C1CC1.O=C(Cl)OCc1ccccc1>>COC(=O)C1C(C2CC2)CC(C2CCN(C(=O)OC(C)(C)C)CC2)CN1C(=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
US20130090333A1,CC1(C)OB(c2ccc3c(c2)OCC(c2c(F)cccc2F)N3)OC1(C)C.Cc1sc(-c2cnccn2)nc1OS(=O)(=O)C(F)(F)F>>Cc1sc(-c2cnccn2)nc1-c1ccc2c(c1)OCC(c1c(F)cccc1F)N2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20140303143A1,CON(C)C(=O)c1cccc2ccncc12.C[Mg]Br>>CC(=O)c1cccc2ccncc12,,C1CCOC1,,,,test
US20030236297A1,CCOC(=O)C(C)C(=O)OCC.ICCc1cccs1>>CCOC(=O)C(C)(CCc1cccs1)C(=O)OCC,,CN(C)C=O,,[H-].[Na+],,test
US20030181494A1,Cc1cc(C)cc(C=C(C(=O)O)c2ccc(O)cc2)c1.O=Cc1ccc(F)cc1>>Cc1cc(C)cc(C=C(C(=O)O)c2ccc(Oc3ccc(C=O)cc3)cc2)c1,,CN(C)C=O,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20020082254A1,Cc1ccc(OC(=O)Cl)cc1.NN1CCc2ccccc2C1>>Cc1ccc(OC(=O)NN2CCc3ccccc3C2)cc1,,CCOCC,,ClCCl,c1ccncc1,test
US20160200719A1,COc1ccc(CN)cc1.Clc1cnnc2ccc(Br)cc12>>COc1ccc(CNc2cnnc3ccc(Br)cc23)cc1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20080096874A1,Nc1ccc(C2CCC3(CC2)OCCO3)nc1.O=C(Cl)OCc1ccccc1>>O=C(Nc1ccc(C2CCC3(CC2)OCCO3)nc1)OCc1ccccc1,,C1CCOC1,,c1ccncc1,,test
US20120108638A1,CCc1cc(-c2nc(-c3cc(OC)nc(C4CCCC4)c3)no2)cc(C)c1OC[C@@H]1CO1.N>>CCc1cc(-c2nc(-c3cc(OC)nc(C4CCCC4)c3)no2)cc(C)c1OC[C@@H](O)CN,,CO,,,,test
US20040110954A1,CCOC(C)=O.CN(C)C=O.N#Cc1ccc([N+](=O)[O-])c(O)c1>>C=CCOc1cc(C#N)ccc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120040954A1,CCOC(=O)c1ccc(N2CCC(NC(=O)c3ccccc3)CC2)cc1>>O=C(NC1CCN(c2ccc(CO)cc2)CC1)c1ccccc1,,C1CCOC1,,CC(C)C[AlH]CC(C)C,,test
US20160016948A1,Cc1nc2cnc(Nc3ccnc(Cl)n3)cc2n1C(C)C.c1c[nH]nn1>>Cc1nc2cnc(Nc3ccnc(-n4nccn4)n3)cc2n1C(C)C,,O,,CN1CCCC1=O,O=C([O-])[O-].[K+].[K+],test
US20130225584A1,Nc1ccnnc1.O=C(O)c1cc(C(F)(F)F)c(C(=O)N2CCCCC2)cc1OCc1ccccc1>>O=C(Nc1ccnnc1)c1cc(C(F)(F)F)c(C(=O)N2CCCCC2)cc1OCc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05021478,CC1(C)CC(O)CC(C)(C)N1OC1CCCCC1.O=C(Cl)CCl>>CC1(C)CC(OC(=O)CCl)CC(C)(C)N1OC1CCCCC1,,CCOCC,ClCCl,CCN(CC)CC,,test
US20110190395A1,CCC=CCC=CCC=CCC=CCCS.CCOC(=O)C(Br)CC>>CC/C=C\C/C=C\C/C=C\C/C=C\CCSC(CC)C(=O)OCC,,CN(C)C=O,,[H-].[Na+],,test
US20140243322A1,CC(C)(C)OC(=O)NCCOS(C)(=O)=O.CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(O)ccc2-n2c(C)nnc21>>CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OCCNC(=O)OC(C)(C)C)ccc2-n2c(C)nnc21,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20140256756A1,CS(=O)(=O)c1cc(F)c(O[C@H]2CCN(C3CCNCC3)C2=O)cc1F.FC(F)(F)c1nnc(Cl)s1>>CS(=O)(=O)c1cc(F)c(O[C@H]2CCN(C3CCN(c4nnc(C(F)(F)F)s4)CC3)C2=O)cc1F,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US05958954,CC1(C)CC(=O)c2cc(O)c(F)cc2S1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC1(C)CC(=O)c2cc(OS(=O)(=O)C(F)(F)F)c(F)cc2S1,,c1ccncc1,,,,test
US20070287724A1,CCOCc1nc2cnc3ccccc3c2n1CC1(O)CCNCC1.O=C(Cl)C1CC1>>O=C(C1CC1)N1CCC(O)CC1,,ClCCl,,CCN(CC)CC,,test
US04327026,CC(=O)c1ccc2c(c1)C(c1ccccc1F)=NC(C)(C)C(=O)N2C.NO>>CC(=NO)c1ccc2c(c1)C(c1ccccc1F)=NC(C)(C)C(=O)N2C,,c1ccncc1,,Cl,,test
US20040176370A1,CC(CCN1CCC(C(N)=O)CC1)OCc1ccccc1>>CC(CCN1CCC(CN)CC1)OCc1ccccc1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US05891901,CSc1ccc2ccn(C)c2c1.O=C(Cl)C(=O)Cl>>CSc1ccc2c(C(=O)C(=O)Cl)cn(C)c2c1,,CCOCC,,,,test
US20050148603A1,CN(C)C=C1CCc2nonc2C1=O.N=C(N)Nc1cccc(O)c1>>Oc1cccc(Nc2ncc3c(n2)-c2nonc2CC3)c1,,CN(C)C=O,,,,test
US20020036285A1,CC(=O)OC(C)=O.Cc1cc(O)ccc1Cl>>CC(=O)Oc1ccc(Cl)c(C)c1,O=S(=O)(O)O,O,,,,test
US04267184,COc1ccc(-c2cc[nH]c2-c2ccc(OC)cc2)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccc(-c2cc(C(=O)C(F)(F)F)[nH]c2-c2ccc(OC)cc2)cc1,,CCOCC,,CN(C)c1ccccc1,,test
US03984460,CCCCCCCCCCCCCCCCCCN.COC(=O)CCc1cc(C(C)(C)C)c(O)c(C)c1C>>CCCCCCCCCCCCCCCCCCNC(=O)CCc1cc(C(C)(C)C)c(O)c(C)c1C,,CO,,,,test
US20120010247A1,BrCC1CCC1.OCc1ccc(O)cc1>>OCc1ccc(OCC2CCC2)cc1,,CCO,,O,O=C([O-])[O-].[K+].[K+],test
US20110218192A1,C[Si](C)(C)N=C=N[Si](C)(C)C.O=C1CC2(CCOC2)Oc2ccc(Br)cc21>>N#C/N=C1\CC2(CCOC2)Oc2ccc(Br)cc21,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20080255230A1,N#CN=C(Oc1ccccc1)Oc1ccccc1.NCCF>>N#CN=C(NCCF)Oc1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US05001125,O=C(Cl)c1ccccc1.OC1CCN(Cc2ccccc2)CC1>>Cl.O=C(OC1CCN(Cc2ccccc2)CC1)c1ccccc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20090054425A1,Cc1ccc(S(=O)(=O)n2ccc3c(Nc4ccc5c(cnn5C)c4)nc(Cl)nc32)cc1.NC(=O)c1ccc(N)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(Nc4ccc5c(cnn5C)c4)nc(Nc4ccc(C(N)=O)cc4)nc32)cc1,,CCCCO,,C[Si](C)(C)Cl,,test
US20140088085A1,CCCN(CCCO[Si](C)(C)C(C)(C)C)C(=O)C1=Cc2ccc(-c3ccc(C(=O)N4CCCC4)cc3)cc2N=C(NC(=O)OC(C)(C)C)C1>>CCCN(CCCO[Si](C)(C)C(C)(C)C)C(=O)C1=Cc2ccc(-c3ccc(C(=O)N4CCCC4)cc3)cc2N=C(NC)C1,,CCOC(C)=O,CN(C)C=O,CN,,test
US06884821B1,CCOC(=O)C(Cc1ccc(O)c(CNC(=O)OC(C)(C)C)c1)OC(C)C.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)C(Cc1ccc(OS(=O)(=O)C(F)(F)F)c(CNC(=O)OC(C)(C)C)c1)OC(C)C,,CCOC(C)=O,c1ccncc1,,,test
US04317914,CC1(C)N=C1c1ccccc1.CCN(CC)c1ccc(C=O)cc1>>CCN(CC)c1ccc(C2OC(C)(C)N=C2c2ccccc2)cc1,,c1ccccc1,,O,,test
US20150225412A1,CC(C)(C)OC(=O)N1CCC(N)CC1.O=Cc1ccc(F)c([N+](=O)[O-])c1>>CC(C)(C)OC(=O)N1CCC(Nc2ccc(C=O)cc2[N+](=O)[O-])CC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20130203076A1,CC=C1N(C)C(C)CC1(c1ccccc1)c1cccc(OCC(=O)NCCNC(=O)OC(C)(C)C)c1.O=C(O)C(F)(F)F>>CC=C1N(C)C(C)CC1(c1ccccc1)c1cccc(OCC(=O)NCCN)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20050250782A1,COC(=O)c1ccc(Cl)nc1Nc1ccc(Br)cc1F.O=C(O)c1ccc(Cl)nc1Nc1ccc(Br)cc1F>>O=C(O)c1ccc(=O)[nH]c1Nc1ccc(Br)cc1F,,CO,c1ccccc1,C[Si](C)(C)C=[N+]=[N-],,test
US20150087585A1,C1CCNC1.C[C@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1C(=O)O>>C[C@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1C(=O)N1CCCC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04395406,CSc1nc(=O)[nH]cc1F.OCCBr>>CSc1nc(=O)n(CCO)cc1F,,CN(C)C=O,,[K],,test
US20150376130A1,CCOC(=O)c1cccnc1Cl.NCc1cccc(F)c1>>CCOC(=O)c1cccnc1NCc1cccc(F)c1,,O,,CCO,,test
US04810800,COC(CN)OC.NCc1cccs1.S=C(n1ccnc1)n1ccnc1>>S=c1[nH]ccn1Cc1cccs1,,Cc1ccccc1,,,,test
US20110275611A1,N#Cc1ccc(-c2cc(-c3ccccc3)nc(N)n2)cc1F.NN>>Nc1nc(-c2ccccc2)cc(-c2ccc3c(N)n[nH]c3c2)n1,,CCO,,O,,test
US20130129753A1,CNC(C)(C)C(=O)O.O=C(Cl)CCCCCN1C(=O)C=CC1=O>>CN(C(=O)CCCCCN1C(=O)C=CC1=O)C(C)(C)C(=O)O,,ClCCl,,CCN(CC)CC,,test
US20130196974A1,CC(C)OC(=O)C1(C(=O)OC(C)C)CC(F)(F)C1>>O=C(O)C1(C(=O)O)CC(F)(F)C1,,CO,,[Na+].[OH-],,test
US05554607,CCOC(=O)CNC.S=C=Nc1cccnc1>>CN1CC(=O)N(c2cccnc2)C1=S,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US04554279,CC(Br)CCCN1C(=O)c2ccccc2C1=O.CCCCCCCCCCOc1c(OC)cc(N)c2ncccc12>>CCCCCCCCCCOc1c(OC)cc(NC(C)CCCN2C(=O)c3ccccc3C2=O)c2ncccc12,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20130048949A1,CCOP(=O)(OCC)c1ccc(C)cc1.O=C1CCC(=O)N1Br>>CCOP(=O)(OCC)c1ccc(CBr)cc1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20030229094A1,C=O.NC(=O)c1cccc(Cl)c1.c1ccc(N2CCNCC2)nc1>>O=C(NCN1CCN(c2ccccn2)CC1)c1cccc(Cl)c1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US05929120,CCOC(=O)[C@H](CNC(=O)c1ccc(C=Cc2ccc3cccnc3n2)cc1)NS(=O)(=O)c1ccccc1>>CCOC(=O)[C@H](CNC(=O)c1ccc(CCc2ccc3c(n2)NCCC3)cc1)NS(=O)(=O)c1ccccc1,[Pd],CCO,,,,test
US20150175602A1,CC(C)Nc1nc2c(nc1N1CCN(Cc3ccc(F)cc3F)CC1)CCNC2.CCC(=O)OC(=O)CC>>CCC(=O)N1CCc2nc(N3CCN(Cc4ccc(F)cc4F)CC3)c(NC(C)C)nc2C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20140243310A1,O=C(NC1CC2(CCC1O)OCCO2)c1ccc(OCC2CC2)c(F)c1>>Fc1cc(-c2nc3c(o2)CCC2(C3)OCCO2)ccc1OCC1CC1,,CS(C)=O,,CCN(CC)CC,O,test
US20040224973A1,CS(=O)(=O)n1cc(C=O)c2cccnc21.O=C(OO)c1cccc(Cl)c1>>CS(=O)(=O)N1CC(=O)c2cccnc21,,ClCCl,,,,test
US04450169,CC1(C)[C@@H](C=C(Br)Br)[C@H]1C(=O)Cl.OCc1cnc(Oc2ccccc2)s1>>CC1(C)[C@@H](C=C(Br)Br)[C@H]1C(=O)OCc1cnc(Oc2ccccc2)s1,,c1ccccc1,,Cl,c1ccncc1,test
US20110009454A1,CCOc1cccc(O)c1.N#Cc1cccc(F)c1>>CCOc1cccc(Oc2cccc(C#N)c2)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20090118275A1,COc1ccncc1B(O)O.Clc1nc(N2CCOCC2)c2sc(I)nc2n1>>COc1ccncc1-c1nc2nc(Cl)nc(N3CCOCC3)c2s1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US20120223634A1,CC(C)c1cc(-c2ccccc2)cc(C(C)C)c1N.COc1cccc(C(=O)Cl)c1>>COc1cccc(C(=O)Nc2c(C(C)C)cc(-c3ccccc3)cc2C(C)C)c1,,ClCCl,,O,c1ccncc1,test
US20080181866A1,N#Cc1ccc([C@@H]2NC(C(=O)O)CS2)cc1.O=C(Cl)OCc1ccccc1>>N#Cc1ccc([C@H]2SCC(C(=O)O)N2C(=O)OCc2ccccc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20040092582A1,COc1cc(C=O)cc2c1OC(C)(C)C2.NO>>COc1cc(C#N)cc2c1OC(C)(C)C2,,O=CO,,Cl,[K+].[OH-],test
US20060189663A1,COc1ccc(NC2=C(c3ccccc3)C(=O)N(Cc3cccnc3)C2=O)cc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COc1ccc(NC2=C(c3ccccc3)C(=O)N(Cc3cccnc3)C2=S)cc1,,Cc1ccccc1,,,,test
US20100093724A1,C[Si](C)(C)C#N.[O-][n+]1ccc2c(cnn2-c2ccc(F)cc2)c1>>N#Cc1nccc2c1cnn2-c1ccc(F)cc1,,CC#N,O,CCN(CC)CC,,test
US20120259123A1,CCCCC(C)(C)c1ccc(CNCc2cccc(N(CC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n2)cc1.Cc1ccc(S(=O)(=O)Cl)o1>>CCCCC(C)(C)c1ccc(CNC(c2cccc(N(CC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n2)S(=O)(=O)c2ccc(C)o2)cc1,,O,,CCN(CC)CC,ClCCl,test
US05725798,CCCCCCCCCCOc1ccc2cc(C(=O)Oc3ccc(C(=O)OCc4ccccc4)cc3)ccc2c1>>CCCCCCCCCCOc1ccc2cc(C(=O)Oc3ccc(C(=O)O)cc3)ccc2c1,[Pd],C1CCOC1,,[H][H],,test
US20040102494A1,O=C1CNCN1.O=[N+]([O-])c1ccc(F)c(F)c1>>O=C1CN(c2ccc([N+](=O)[O-])cc2F)CN1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20100144758A1,Cc1cccc(N)c1.O=C(CBr)c1ccc(F)cc1>>Cc1cccc(NCC(=O)c2ccc(F)cc2)c1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20140187788A1,Cc1ccc(S(=O)(=O)OS(=O)(=O)c2ccc(C)cc2)cc1.OC1CSC1.c1ccncc1>>C1=CN=C[CH2+]=C1.C1CSC1.Cc1ccc(S(=O)(=O)O)cc1,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,,test
US05026856,CC1COc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23.OCc1cccc2c1CNC2>>CC1COc2c(N3Cc4cccc(CO)c4C3)c(F)cc3c(=O)c(C(=O)O)cn1c23,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20070179191A1,CCCCc1nc(-c2ccc(C(F)(F)F)cc2)sc1CO.N#Cc1ccc(F)cc1C(F)(F)F>>CCCCc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1ccc(C#N)c(C(F)(F)F)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160194284A1,Nc1cccc(C(F)(F)F)c1.O=C(Nc1ccc(Cl)cc1)Nc1cccc(-c2cccc(N3CCCC3)n2)c1>>O=C(Nc1cccc(-c2cccc(N3CCCC3)n2)c1)Nc1ccccc1C(F)(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05260377,ClCCC[Si](Cl)(Cl)c1ccccc1>>Cl[Si]1(c2ccccc2)CCC1,II,CCOCC,,[Mg],,test
US20100303928A1,CCOC(=O)c1nc(I)c2c(-c3cccs3)noc2c1O.OB(O)C1CC1>>CCOC(=O)c1nc(C2CC2)c2c(-c3cccs3)noc2c1O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,Cc1ccccc1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US06329380B1,CC(Nc1nccc(-n2cnc3ccccc32)n1)C1CCCNC1.CI>>CC(Nc1nccc(-n2cnc3ccccc32)n1)C1CCCN(C)C1,,CCO,,,,test
US04200466,CCCCCCCCCCCCNC(=O)COc1ccc(O)cc1NCC(=O)OCC>>CCCCCCCCCCCCNC(=O)COc1ccc(O)cc1NCC(=O)O,,CO,O,Cl,[Na+].[OH-],test
US20160244451A1,COCc1ncc(-c2ccc(S(=O)(=O)Nc3cc(F)c(C(=O)OC)cc3F)cc2)cn1>>COCc1ncc(-c2ccc(S(=O)(=O)Nc3cc(F)c(C(=O)O)cc3F)cc2)cn1,,CO,,Cl,[Li+].[OH-],test
US20030144283A1,CCOCc1nc2c(N)nc3ccccc3c2n1CCN.O=C(O)C(CCC[C@@H]1SC[C@H]2[C@@H]1NC(=O)N2O)N1C(=O)CCC1=O>>CCOCc1nc2c(N)nc3ccccc3c2n1CCNC(=O)CCCCC1SCC2NC(=O)NC21,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20130102576A1,CS(=O)(=O)N(Cc1cccs1)c1ccc2c(c1)C(=O)N(CC(=O)O)C2=O.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>CS(=O)(=O)N(Cc1cccs1)c1ccc2c(c1)C(=O)N(CC(=O)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC3CC3)c1)C2=O,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20130102576A1,BrC(Br)(Br)Br.CC(C)(C)OC(=O)CN1C(=O)c2ccc(N(CCO)S(C)(=O)=O)cc2C1=O>>CC(C)(C)OC(=O)CN1C(=O)c2ccc(N(CCBr)S(C)(=O)=O)cc2C1=O,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20040102441A1,Nc1cc2cn[nH]c2cc1Cl.O=C(O)c1ccccc1NCc1ccncc1>>O=C(Nc1cc2cn[nH]c2cc1Cl)c1ccccc1NCc1ccncc1,,CN(C)C=O,O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090247573A1,CCCCC1(N(C)C)CC=C(c2[nH]c3ccccc3c2CCN2C(=O)c3ccccc3C2=O)CC1.Cc1c[nH]c2ccc(F)cc12.O=S(=O)(O)C(F)(F)F>>CCCCC1(N(C)C)CCC(c2[nH]c3ccc(F)cc3c2C)(c2[nH]c3ccc(F)cc3c2C)CC1,,ClCCl,,,,test
US20060252812A1,CCCCCCN1C(=O)C(CC(=O)[O-])(c2cc3c(cc2O)OCO3)c2ccccc21>>CCCCCCN1C(=O)C2(CC(=O)Oc3cc4c(cc32)OCO4)c2ccccc21,,C1CCOC1,O,[Li+].[OH-],,test
US20160264567A1,CCCC[Sn](CCCC)(CCCC)c1cnc(C(F)(F)F)s1.O=C1c2ccccc2C(=O)N1Cc1cc(Cl)ncn1>>O=C1c2ccccc2C(=O)N1Cc1cc(-c2cnc(C(F)(F)F)s2)ncn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,CN(C)C=O,,,test
US20080194552A1,COc1ccc(C#Cc2cnc(N)nc2)cc1N.O=C(O)CCc1ccc(C(F)(F)F)cc1>>COc1ccc(C#Cc2cnc(N)nc2)cc1NC(=O)CCc1ccc(C(F)(F)F)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06352982B1,CC(C)(C)OC(=O)NCc1ccc(C(=O)c2cc(Cl)ccc2N)cc1>>CC(C)(C)OC(=O)NCc1ccc(C(O)c2cc(Cl)ccc2N)cc1,,CCOC(C)=O,,CO,[BH4-].[Na+],test
US20140357612A1,CCN(C)S(=O)(=O)Nc1cccc(-c2nc(C(C)(C)C)sc2-c2ccnc(Cl)n2)c1F.N>>CCN(C)S(=O)(=O)Nc1cccc(-c2nc(C(C)(C)C)sc2-c2ccnc(N)n2)c1F,,CO,,,,test
US20090306016A1,CCOC(=O)CCCCCCOc1ccccc1>>O=CCCCCCCOc1ccccc1,,C1CCOC1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20160264594A1,C=CCOC/C=C/[C@H]1CC(=C)[C@H](CC[C@H]2C[C@@H](C)C(=C)[C@@H](C[C@@H]3O[C@H](C[C@@H](CO[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@H](OC)[C@H]3CS(=O)(=O)c3ccccc3)O2)O1>>C=CCOC/C=C/[C@H]1CC(=C)[C@H](CC[C@H]2C[C@@H](C)C(=C)[C@@H](C[C@@H]3O[C@H](C[C@H](O)CO)[C@H](OC)[C@H]3CS(=O)(=O)c3ccccc3)O2)O1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20060166997A1,CC(=O)Cl.CC(C)Oc1ccccc1O>>CC(=O)Oc1ccccc1OC(C)C,,CCOCC,ClCCl,c1ccncc1,,test
US20100041657A1,Cc1cccc2cccc(O)c12.O=C=Nc1ccc(S(=O)(=O)C(F)(F)F)cc1Cl>>Cc1cccc2ccc(C(=O)Nc3ccc(S(=O)(=O)C(F)(F)F)cc3Cl)c(O)c12,,CO,Cc1ccccc1,ClB(Cl)Cl,,test
US20120264748A1,BrP(Br)Br.OCc1cccc(-c2cnccn2)c1>>BrCc1cccc(-c2cnccn2)c1,,C1CCOC1,,,,test
US04692442,CC(=O)S[C@@H]1[C@@H](OC(=O)COc2ccccc2)C(=O)N1C(O)C(=O)OCc1ccc([N+](=O)[O-])cc1.O=S(Cl)Cl>>CO[C@H]1C(=O)N(C(Cl)C(=O)OCc2ccc([N+](=O)[O-])cc2)[C@@H]1SC(C)=O,,C1COCCO1,,,,test
US20020099071A1,NNc1cccc(F)c1.O=C1Nc2ccc3ncsc3c2C1=O>>O=C1Nc2ccc3ncsc3c2C1=NNc1cccc(F)c1,,CCO,,Cl,,test
US05714489,CC(=O)O.CCn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(N)cc21.COC1CCC(OC)O1>>CCn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(-n3cccc3)cc21,,CC(=O)O,,,,test
US05013749,Fc1ccc(-c2nc(C(F)(F)F)[nH]c2-c2ccc(F)cc2)cc1.N#CC(Br)CBr>>N#C/C=C/n1c(C(F)(F)F)nc(-c2ccc(F)cc2)c1-c1ccc(F)cc1,,CN(C)C=O,,CCN(CC)CC,O=C([O-])[O-].[K+].[K+],test
US20130261159A1,CC(C)(O)c1nc(CO[Si](C)(C)C(C)(C)C)co1.CI>>COC(C)(C)c1nc(CO[Si](C)(C)C(C)(C)C)co1,,ClCCl,,N#N,,test
US20150329538A1,CCn1c(=O)[nH]c2c(Br)cccc2c1=O.O=P(Cl)(Cl)Cl>>CCn1c(Cl)nc2c(Br)cccc2c1=O,,O,,CCN(C(C)C)C(C)C,[Na+].[OH-],test
US05451343,COS(=O)(=O)OC.O=c1c2ccc(O)cc2oc2cc(O)ccc12>>COc1ccc2c(=O)c3ccc(O)cc3oc2c1,,CCO,O,,,test
US20020115674A1,CC(C)(C)OC(=O)NC1CCN(c2cc3c(cc2F)c(=O)n(OCc2ccccc2)c(=O)n3-c2ccc(F)cc2)C1>>CC(C)(C)OC(=O)NC1CCN(c2cc3c(cc2F)c(=O)n(O)c(=O)n3-c2ccc(F)cc2)C1,[Pd],,,,,test
US20100137290A1,C=CCCCC(=O)Cl.COc1ccc2nccc(N)c2n1>>C=CCCCC(=O)Nc1ccnc2ccc(OC)nc12,,ClCCl,,,,test
US20140315889A1,CC1(C)CC(=O)C2c3c(F)cccc3NC2C1.CCOC(=O)CCCCCBr>>CCOC(=O)CCCCCN1c2cccc(F)c2C2C(=O)CC(C)(C)CC21,,CN(C)C=O,,[H-].[Na+],,test
US20060026777A1,O=[N+]([O-])c1ccc(NC(CO)(CO)CO)cc1>>Nc1ccc(NC(CO)(CO)CO)cc1,[Pd],O,,C1=CCCCC1,,test
US05254755,CCC(F)(F)C(F)(F)C(=CF)C(F)(F)F.O=S(=O)(O)O>>CCC(F)(F)C(F)(F)C(O)(CF)C(F)(F)F,,O,,,,test
US20110136780A1,CCC(=O)O.CCC1(N2Cc3c[nH]c4nccc(c34)C2=O)CCNCC1>>CCC(=O)N1CCC(CC)(N2Cc3c[nH]c4nccc(c34)C2=O)CC1,CN(C)c1ccncc1,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20160244415A1,COC(=O)C(C)NC(=O)c1cn(-c2ccc3c(c2)ncn3C)c(=O)n(Cc2cccc(C(F)(F)F)c2C)c1=O>>Cc1c(Cn2c(=O)c(C(=O)N[C@@H](C)C(=O)O)cn(-c3ccc4c(c3)ncn4C)c2=O)cccc1C(F)(F)F,,CC(=O)O,Cl,O,,test
US05410052,NCCCN.O=Cc1ccccn1>>c1ccc(C2NCCCN2)nc1,,c1ccccc1,,,,test
US20100130492A1,CC(=O)N1CCN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC(F)(F)F)C[C@H]1C.CS(=O)(=O)O>>CC(=O)N1CCN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC(F)(F)F)C[C@H]1C.CS(=O)(=O)O,,CO,ClCCl,,,test
US20080090855A1,CC(C)(C)c1ccc(CBr)cc1.O=C1NCCN1>>CC(C)(C)c1ccc(CN2CCNC2=O)cc1,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20090047244A1,COc1ccc(CO)cc1.COc1ccc2c(Cl)cc(Cl)nc2c1C>>COc1ccc(COc2cc(Cl)nc3c(C)c(OC)ccc23)cc1,,CN(C)C=O,O,C1COCCOCCOCCOCCO1,[H-].[Na+],test
US20110105566A1,Cn1nnnc1C(=NOCc1cccc(CN2C(=O)c3ccccc3C2=O)n1)c1ccccc1>>Cn1nnnc1C(=NOCc1cccc(CN)n1)c1ccccc1,,C1CCOC1,,NN,O,test
US20120238541A1,COc1cccnc1NN.O=C(n1ccnc1)n1ccnc1>>COc1cccn2c(=O)[nH]nc12,,C1CCOC1,,,,test
US20050267095A1,C=O.O=C(N1CCNCC1)C1(c2ccc(OCCCN3CCCOCC3)cc2)CCOCC1>>CN1CCN(C(=O)C2(c3ccc(OCCCN4CCCOCC4)cc3)CCOCC2)CC1,,ClCCl,,CC(=O)O,,test
US20090318688A1,COC(=O)c1cc(CN(C)C=O)ccc1[N+](=O)[O-]>>COC(=O)c1cc(CN(C)C=O)ccc1N,[Pd],CO,,[H][H],,test
US05021420,O=S1(=O)c2cccc3cccc(c23)N1CCCCl.Oc1ccc2[nH]cc(C3=CCNCC3)c2c1>>O=S1(=O)c2cccc3cccc(c23)N1CCCN1CC=C(c2c[nH]c3ccc(O)cc23)CC1,,C1CCOC1,CN(C)C=O,O=C([O-])O.[Na+],,test
US20100105744A1,CC(O)(c1ccc(C(F)(F)F)cc1F)C1CC1.CSCc1cccc2cc[nH]c12>>CSCc1cccc2c(C(C)(c3ccc(C(F)(F)F)cc3F)C3CC3)c[nH]c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040229861A1,COc1ccc(CNc2ncccc2CNC2CCN(C(=O)OC(C)(C)C)CC2)c(OC)c1.O=C(n1ccnc1)n1ccnc1>>COc1ccc(CN2C(=O)N(C3CCN(C(=O)OC(C)(C)C)CC3)Cc3cccnc32)c(OC)c1,,CN(C)C=O,O,,,test
US07002011B1,CSc1nc(N)nc(C(C)F)n1.ClCl>>CC(F)c1nc(N)nc(Cl)n1,,CC(=O)O,,[Na+].[OH-],,test
US20070244095A1,CCOC(=O)CCCBr.COC(=O)c1ccc2c(c1NC(=O)OC(C)C)CCC2>>CCOC(=O)CCCN(C(=O)OC(C)C)c1c(C(=O)OC)ccc2c1CCC2,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20090093512A1,COC(=O)C#Cc1cccc(OC)n1.COCN(Cc1ccccc1)C[Si](C)(C)C>>COC(=O)C1=C(c2cccc(OC)n2)CN(Cc2ccccc2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030040523A1,Nc1nc(SCc2ccccc2)nc(Cl)c1[N+](=O)[O-]>>Nc1nc(SCc2ccccc2)nc(Cl)c1N,[Fe],CCO,O,[Cl-].[NH4+],,test
US20110183982A1,C1CCOC1.CCOC(=O)COc1ccc(SCc2cc(O)cc(Br)c2)cc1C.O=C(N=NC(=O)N1CCCCC1)N1CCCCC1>>CCOC(=O)COc1ccc(SCc2cc(Br)cc(OCC3CC3)c2)cc1C,,C1CCOC1,,CCCCP(CCCC)CCCC,,test
US20140073672A1,CCOC(=O)CBr.COc1ccc(C2=NN(C3CCN(C(=O)c4cc(O)ccc4C)CC3)C(=O)C2(C)C)cc1OC>>CCOC(=O)COc1ccc(C)c(C(=O)N2CCC(N3N=C(c4ccc(OC)c(OC)c4)C(C)(C)C3=O)CC2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120196891A1,Nc1cc(C(F)(F)F)cnc1S.O=Cc1ccncc1F>>Fc1cnccc1-c1nc2cc(C(F)(F)F)cnc2s1,,O,,CS(C)=O,,test
US05608069,BrCCBr.ON=C(c1ccccc1)C(F)(F)F>>FC(F)(F)C(=NOCCBr)c1ccccc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140030221A1,C=CC(C)(C(=O)N1C(=O)OC[C@@H]1C(C)C)C(C)O[Si](C)(C)C(C)(C)C.OO>>C=CC(C)(C(=O)O)C(C)O[Si](C)(C)C(C)(C)C,,C1CCOC1,O,[Li+].[OH-],,test
US20070099967A1,COc1ccc(S(=O)(=O)Cl)cc1.Nc1cccnc1Nc1ccc(O)cc1>>COc1ccc(S(=O)(=O)Nc2cccnc2Nc2ccc(O)cc2)cc1,,C1CCOC1,c1ccncc1,,,test
US05198462,Cc1ccccc1C(=O)c1ccccc1.O=C1CCC(=O)N1Br>>O=C(c1ccccc1)c1ccccc1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US05622976,CCOC(=O)C(N)=NO.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CCOC(=O)C(N)=NOC(=O)c1ccc([N+](=O)[O-])cc1,,C1CCOC1,,,,test
US20150133428A1,COC(CBr)(CBr)OC.N#CCc1cccnc1>>COC1(OC)CC(C#N)(c2cccnc2)C1,,CN(C)C=O,,O,[H-].[Na+],test
US20030087874A1,COC(=O)NCCCCCCC(CCCC(=O)NCCCN[C@H](C(=O)OC(C)(C)C)[C@@H](O)C1O[C@@H](n2ccc(=O)n(Cc3ccc(OC)cc3)c2=O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C)C1c2ccccc2-c2ccccc21>>COc1ccc(Cn2c(=O)ccn([C@@H]3OC([C@H](O)[C@H](NCCCNC(=O)CCCCCCCCCCN)C(=O)OC(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]3O[Si](C)(C)C(C)(C)C)c2=O)cc1,,C1CCNCC1,,,,test
US20020052376A1,COC(=O)c1ccc(C=Cc2ccc(F)cc2)c(C(=O)OC)c1>>COC(=O)c1ccc(CCc2ccc(F)cc2)c(C(=O)OC)c1,[Pd],CCOC(C)=O,,,,test
US20150141400A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1cc(Cl)c(C(F)(F)F)cc1Br.CCOC(=O)c1cc(Br)c(C)c(Cl)c1N>>CCOC(=O)c1cc(Br)c(C)c(Cl)c1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,CC#N,,,,test
US20080070935A1,Cc1cn(-c2ccc3c(N)ncc(C#N)c3c2)c2c1C(=O)CC(C)(C)C2.OO>>Cc1cn(-c2ccc3c(N)ncc(C(N)=O)c3c2)c2c1C(=O)CC(C)(C)C2,,CCO,CS(C)=O,O,[Na+].[OH-],test
US20080221101A1,COC(=O)C1CCN(c2cc(C=O)ccc2Cl)CC1.C[C@@H](N)c1ccccc1>>COC(=O)C1CCN(c2cc(CN[C@H](C)c3ccccc3)ccc2Cl)CC1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20040214832A1,CC(C)(C)OC(=O)N1CC(=O)N(c2ccc(OCCCOCc3ccccc3F)cc2)[C@@H](COc2ccc3ccccc3c2)C1>>O=C1CNC[C@H](COc2ccc3ccccc3c2)N1c1ccc(OCCCOCc2ccccc2F)cc1,,CO,,CC(=O)Cl,,test
US20050137214A1,CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3ncc4ccc(=O)n(C5CCCC5)c4n3)nc2)CC1.Cl>>Cl.O=c1ccc2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n1C1CCCC1,,CO,ClCCl,,,test
US20140155391A1,COC(=O)c1ccc(OC)c(NS(C)(=O)=O)c1.OCCBr>>COC(=O)c1ccc(OC)c(N(CCO)S(C)(=O)=O)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120171119A1,COc1cc2c(cc1OC)CN(CCCCNC(=O)c1cc(C)ccc1O)CC2.OCCOCCCl>>COc1cc2c(cc1OC)CN(CCCCNC(=O)c1cc(C)ccc1OCCOCCO)CC2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090093601A1,CC(C)(Br)C(=O)Oc1cccc(C(=O)Cl)c1.ClCCl>>C1=Cc2ccccc2OC1,,ClCCl,,CCN(CC)CC,,test
US20050119274A1,NC(=O)Cc1nc(N2CCN(Cc3ccccc3)C3(CC3)C2)cc2ccccc12>>NC(=O)Cc1nc(N2CCNC3(CC3)C2)cc2ccccc12,[Pd],CO,,O=C[O-].[NH4+],,test
US20030109626A1,C=CC(=O)NCCO.FC(F)=C(F)C(F)(F)F>>C=CC(=O)NCCOC(F)(F)C(F)C(F)(F)F,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040058965A1,CCOC(=O)CCc1cc(O)ccc1OCC.Cc1oc(-c2ccccc2)nc1COc1cccc(CCl)c1>>CCOc1ccc(OCc2cccc(OCc3nc(-c4ccccc4)oc3C)c2)cc1CCC(=O)O,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20120190680A1,NCC12CC3CC(CC(C3)C1)C2.O=C(O)c1cn(-c2ncccn2)c2ccccc12>>O=C(NCC12CC3CC(CC(C3)C1)C2)c1cn(-c2ncccn2)c2ccccc12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20080275046A1,Cc1nc(-c2ccc(OCCCCl)cc2)sc1C(=O)[O-]>>Cc1nc(-c2ccc(OCCCCl)cc2)sc1C(=O)O,,CO,,[Na+].[OH-],,test
US04093812,N#Cc1cn(-c2ccccn2)nc1-c1ccc([N+](=O)[O-])o1.O=S(=O)(O)O>>NC(=O)c1cn(-c2ccccn2)nc1-c1ccc([N+](=O)[O-])o1,,O,,,,test
US20150050325A1,CC(C)(C)OC(=O)NCC(=O)Nc1cc(-c2nn3c(=O)cc(N4CCN(C(=O)OC(C)(C)C)CC4)nc3s2)ccn1>>NCC(=O)Nc1cc(-c2nn3c(=O)cc(N4CCNCC4)nc3s2)ccn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US03996293,C=CCCCCC.CCCCCC>>C=CC=CCCC.CCCCCC,[Pt],CCCCCC,,,,test
US20040092538A1,Cc1ccc2c([n+]1[O-])NCCOC2>>Cc1ccc2c(n1)NCCOC2,,CC(=O)O,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090099205A1,CC(C)(C)OC(=O)N[C@@H](CNC1CCOCC1)c1ccccc1.O=C(O)C(F)(F)F>>N[C@@H](CNC1CCOCC1)c1ccccc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20160039821A1,CCOC(=O)C1c2c[nH]c3c(=O)n(C)cc(c23)-c2cc(CS(C)(=O)=O)ccc2N1c1ccc(F)cc1F>>Cn1cc2c3c(c[nH]c3c1=O)C(CO)N(c1ccc(F)cc1F)c1ccc(CS(C)(=O)=O)cc1-2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06521395B1,CCCCCCCCCCCCS(=O)(=O)c1ccc(C(=O)OC)cc1>>CCCCCCCCCCCCS(=O)(=O)c1ccc(C(=O)O)cc1,,CO,O,Cl,[K+].[OH-],test
US20040010022A1,CN(C)C(N)=O.O=C(CBr)c1cccc2ccccc12>>CN(C)c1nc(-c2cccc3ccccc23)co1,,CN(C)C=O,,CCOC(C)=O,,test
US20110136763A1,COCOc1cc(Oc2cccc(OCc3ccccc3)c2)cc(C)c1C=O>>Cc1cc(Oc2cccc(OCc3ccccc3)c2)cc(O)c1C=O,,C1CCOC1,,Cl,,test
US20040097499A1,O=C1NS(=O)(=O)CCC1c1ccc(Br)cc1>>O=S1(=O)CCC(c2ccc(Br)cc2)CN1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20120040020A1,CCS(=O)(=O)NC1CC[C@H]2CN(c3cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(-c4nnc(-c5ccc(CN(C)C(=O)OC(C)(C)C)cc5)o4)n3)C[C@@H]12>>CCS(=O)(=O)NC1CC[C@H]2CN(c3cnc(N)c(-c4nnc(-c5ccc(CNC)cc5)o4)n3)C[C@@H]12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120283264A1,O=C(O)Cc1cccc(C#Cc2ccccc2)c1.O=Cc1ccccc1>>O=C(O)[C@@H](c1cccc(C#Cc2ccccc2)c1)[C@@H](O)c1ccccc1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US04339612,CC(C)(C)C1CO1.Oc1ccc(Cl)cc1>>CC(C)(C)C(O)COc1ccc(Cl)cc1,,O,,[Na+].[OH-],,test
US20100105655A1,COc1cc(N(C)CCN(C)CCO)ccc1[N+](=O)[O-]>>COc1cc(N(C)CCN(C)CCO)ccc1N,O=[Pt]=O,CCOC(C)=O,,CCO,,test
US04642313,CCOC(=O)CC(NC(=O)c1ccc(F)cc1)C(=O)c1ccoc1>>CCOC(=O)Cc1nc(-c2ccc(F)cc2)oc1-c1ccoc1,,ClC(Cl)Cl,,O=P(Cl)(Cl)Cl,,test
US20080280959A1,CCI.CN(C)C=O.O=C(O)c1cccc(OC(F)(F)F)c1O>>CCOc1cc(OC(F)(F)F)ccc1C(=O)OC,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100093767A1,CC(C)[C@@H](NC(=O)OC(C)(C)C)C(=O)Nc1ccccc1NCc1ccccc1>>CC(C)[C@@H](NC(=O)OC(C)(C)C)c1nc2ccccc2n1Cc1ccccc1,,CC(=O)O,CCO,,,test
US20070238726A1,COc1ccc(Cn2nc(C3CCN(C(=O)OC(C)(C)C)CC3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1>>COc1ccc(Cn2nc(C3CCNCC3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070173498A1,CN(C)CC1=Cc2ccc(N)cc2CC1.O=S(=O)(Cl)c1ccc(-c2ccccc2)cc1>>CN(C)CC1CCc2cc(NS(=O)(=O)c3ccc(-c4ccccc4)cc3)ccc2C1.Cl,,CC#N,,CCN(CC)CC,,test
US04146721,CCOC(=O)CC(C(=O)c1ccccc1)C(=O)c1ccccc1.NNc1cccnc1>>O=C(O)Cc1c(-c2ccccc2)nn(-c2cccnc2)c1-c1ccccc1,,CC(=O)O,,,,test
US20040092543A1,COC(=O)CBr.NC(=O)c1cccc2c1c1c(O)c3c(cc1n2Cc1ccccc1)CCCC3>>COC(=O)COc1c2c(cc3c1c1c(C(N)=O)cccc1n3Cc1ccccc1)CCCC2,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050137224A1,CCOC(=O)[C@@H]1[C@@H]2C[C@@H](O)[C@@H]([C@H]2I)N1[C@H](C)c1ccccc1>>CCOC(=O)[C@@H]1[C@@H]2C[C@@H](O)[C@@H](C2)N1[C@H](C)c1ccccc1,,Cc1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,CCCC[SnH](CCCC)CCCC,test
US04533731,CCN(CC)CCCNc1n[nH]c2cccc(Cl)c12.Cl>>CCN(CC)CCCNc1n[nH]c2cccc(Cl)c12.Cl,,CCO,,CCOCC,,test
US20080009530A1,CC(=O)OC(C)=O.CCCCCS(=O)(=O)NC(=O)/C=C/c1ccc(OCCOC)cc1Oc1ncc(N)cc1C>>CCCCCS(=O)(=O)NC(=O)/C=C/c1ccc(OCCOC)cc1Oc1ncc(NC(C)=O)cc1C,CN(C)c1ccncc1,c1ccncc1,,Cl,Cl,test
US05627215,C=CCN(CCCN(C/C=C/CN(CCCNC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.CCI>>C=CCN(CCCN(C/C=C/CN(CCCN(CC)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20120157479A1,C1CCOC1.CC(C)OC(=O)/N=N/C(=O)OC(C)C.O=C(O)c1ccccc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CC[C@H]1CN(C(=O)OCc2ccccc2)C[C@H]1OC(=O)c1ccccc1,,C1CCOC1,,,,test
US20140179695A1,C1CCOC1.O=C1CC2(CCC2)Oc2ccc(Br)cc21.OCn1nnc2ccccc21>>O=C1c2cc(Br)ccc2OC2(CCC2)C1(CO)CO,,C1CCOC1,CCOC(C)=O,CC(C)(C)[O-].[K+],,test
US20080300242A1,CC(C)(C)OC(=O)N1CCC(N2CCN(CCF)CC2)CC1>>FCCN1CCN(C2CCNCC2)CC1,,CO,Cl,,,test
US20090275570A1,CC(C)(C)OC(=O)N1CCC[C@H](O)C1.N#Cc1cnc(Cl)c2cc(Br)sc12>>CC(C)(C)OC(=O)N1CCC[C@H](Oc2ncc(C#N)c3sc(Br)cc23)C1,,C1CCOC1,O,[H-].[Na+],,test
US20090028821A1,O=C(O)Cc1cccs1.O=[N+]([O-])c1ccc(CBr)cc1>>CC(=O)Sc1ccc([N+](=O)[O-])cc1,,Cc1ccccc1,,C1CCOC1,CCN(CC)CC,test
US20070167506A1,CS(=O)(=O)CCN.O.O=C(Cl)CCCl>>CC(Cl)OC(=O)NCCS(C)(=O)=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040092502A1,CCOC(=O)[C@@]12CC(=O)C[C@@H]1c1cccc3c1N(CCC3)C2=O>>O=C1C[C@H]2C(=O)N3CCCc4cccc(c43)[C@H]2C1,,C1COCCO1,O,Cl,,test
US05015637,O=Cc1cccn1NCc1ccncc1F>>OCc1cccn1NCc1ccncc1F,,CCO,,[BH4-].[Na+],,test
US20070032519A1,NCc1ccc(Cl)cc1.O=Cc1sc(Cl)nc1Cl>>O=Cc1sc(NCc2ccc(Cl)cc2)nc1Cl,,C1CCOC1,,CCN(C(C)C)C(C)C,O,test
US20140187553A1,CNC(=O)c1cccc(-c2cn(S(=O)(=O)c3ccc(C)cc3)c3ccc(-c4nnc(NC(C)C)o4)cc23)n1>>CNC(=O)c1cccc(-c2c[nH]c3ccc(-c4nnc(NC(C)C)o4)cc23)n1,,C1COCCO1,,[Na+].[OH-],,test
US20040235822A1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4nncn4CC)cc2)CCN3CCC)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4nncn4CC)cc2)CCN3CCC)cc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20150353553A1,C[C@@H]1CC[C@@H](Cn2cnc3nc(C#N)nc(-c4cncc(Cl)c4)c32)CC1.O=C1CCC(=O)N1Br>>C[C@@H]1CC[C@@H](Cn2c(Br)nc3nc(C#N)nc(-c4cncc(Cl)c4)c32)CC1,,ClC(Cl)Cl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20120029190A1,CCOC(=N)c1ccccn1.NC1CCN(C(=O)OCc2ccccc2)CC1N>>O=C(OCc1ccccc1)N1CCC2N=C(c3ccccn3)NC2C1,,CCO,,,,test
US20130225554A1,CC(C)(C)OC(=O)N1CC(C(=O)NNC(=O)[C@H]2CC[C@H]3CN2C(=O)N3OS(=O)(=O)O)C1>>O=C(NNC(=O)[C@H]1CC[C@H]2CN1C(=O)N2OS(=O)(=O)O)C1CNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080146523A1,Nc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.O=C(Cl)c1ccccc1>>O=C(Nc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20150057265A1,CC1CC(c2ccncc2N)=CC(O[Si](C)(C)C(C)(C)C)C1>>CC1CC(O[Si](C)(C)C(C)(C)C)CC(c2ccncc2N)C1,[Pd],CO,,,,test
US20090099231A1,N.O=C1NCCc2c1ccc(F)c2F>>Nc1ccc2c(c1F)CCNC2=O,,CO,,,,test
US20100048547A1,C1COCCN1.CC(C)(C)C(=O)Nc1ccc(-c2nc(Cl)cc(Cl)n2)cn1>>CC(C)(C)C(=O)Nc1ccc(-c2nc(Cl)cc(N3CCOCC3)n2)cn1,,CN1CCCC1=O,,CCN(CC)CC,,test
US20070105904A1,C#Cc1ccc(N)nc1N.Cc1ccc(Cc2ccc(CC(Cl)=NO)cc2)o1>>Cc1ccc(Cc2ccc(Cc3cc(-c4ccc(N)nc4N)on3)cc2)o1,,O,,C1CCOC1,CCN(CC)CC,test
US20090048301A1,O=[N+]([O-])c1ccccc1-c1cnc(Nc2ccc3c(c2)OCCO3)o1>>Nc1ccccc1-c1cnc(Nc2ccc3c(c2)OCCO3)o1,[Pd],CO,,,,test
US06444656B1,CC(=O)OCC1OC(OC(C)=O)C2OC(C)(C)OC12.CC(C)OP(OC(C)C)OC(C)C>>CC(=O)OCC1OC(P(=O)(OC(C)C)OC(C)C)C2OC(C)(C)OC12,,ClCCl,,C[Si](C)(C)I,,test
US04032322,CC(C)C(N)=C(C#N)C#N.S>>CC(C)C(N)=C(C#N)C(N)=S,,c1ccncc1,,,,test
US20030144297A1,Clc1cncc(Cl)n1.N[C@@H]1c2ccccc2C[C@@H]1O>>O[C@H]1Cc2ccccc2[C@H]1Nc1cncc(Cl)n1,,CCCCO,,CCN(CC)CC,,test
US20050054851A1,CC(C)(O)C#N.O=C1CCN(Cc2ccccc2)CC1>>N#CC1(O)CCN(Cc2ccccc2)CC1,,CCO,CCOCC,O=C([O-])[O-].[K+].[K+],,test
US20100216803A1,COc1ccc(COC(=O)[C@@H]2CCC[C@@H]2NC(=O)[C@H](CCCNC(=O)OCc2ccccc2)NC(=O)OC(C)(C)C)cc1>>COc1ccc(COC(=O)[C@@H]2CCC[C@@H]2NC(=O)[C@@H](N)CCCNC(=O)OCc2ccccc2)cc1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100305070A1,CCOC(CBr)OCC.COc1cc(C=O)c(O)c(OC)c1>>CCOC(COc1c(C=O)cc(OC)cc1OC)OCC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090215742A1,O=C(O)c1cc(Cl)ccc1O.c1ccc2c(c1)CNC2>>O=C(c1cc(Cl)ccc1O)N1Cc2ccccc2C1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US05610141,CC(C)(C)OC(=O)N[C@@H](CCNC[C@H](NC(=O)OC(C)(C)C)C(=O)O)C(=O)O.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](CCN(C[C@H](NC(=O)OC(C)(C)C)C(=O)O)C(=O)OCc1ccccc1)C(=O)O,,C1COCCO1,O,O=C([O-])O.[Na+],,test
US20070149608A1,COC(=O)CCc1ccc(OCc2cccc(-c3ccc(OC4CCCCO4)cc3C)c2)cc1>>COC(=O)CCc1ccc(OCc2cccc(-c3ccc(O)cc3C)c2)cc1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20080275116A1,O=C(O)Cc1ccccc1OCc1ccccc1.O=C1CCC(=O)N1Br>>O=C(O)Cc1cc(Br)ccc1OCc1ccccc1,,CCOC(C)=O,,ClCCl,,test
US04407811,Cl.O=C1NC(=O)C(c2ccccc2[N+](=O)[O-])O1>>Cl.Nc1ccccc1C1OC(=O)NC1=O,[Fe],CO,,,,test
US20080255133A1,CN1C=NC2C(Cl)=C(Nc3ccc(I)cc3F)C(NS(=O)(=O)C3(CCO[Si](C)(C)C(C)(C)C)CC3)=NC21>>CN1C=NC2C(Cl)=C(Nc3ccc(I)cc3F)C(NS(=O)(=O)C3(CCO)CC3)=NC21,,C1CCOC1,,Cl,,test
US20150065468A1,COc1cc2nc(-c3ccc(CC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c(F)c3)cnc2cc1O.ClCCBr>>COc1cc2nc(-c3ccc(CC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c(F)c3)cnc2cc1OCCCl,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100303758A1,CC(=O)OC(C)=O.O=C(O)c1ccc(Oc2ccc(Cl)c(O)c2)cc1>>CC(=O)Oc1cc(Oc2ccc(C(=O)O)cc2)ccc1Cl,,c1ccncc1,,,,test
US20030232932A1,COc1cccc(C(C)(O)c2cccc(OC)c2)c1>>C=C(c1cccc(OC)c1)c1cccc(OC)c1,,CC(=O)O,O,II,,test
US20060142202A1,CCOCc1nc2cnc3ccccc3c2n1CC(C)(C)NC(=O)CCC(=O)NNC(=O)OC(C)(C)C>>CCOCc1nc2cnc3ccccc3c2n1CC(C)(C)NC(=O)CCC(=O)NN,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110039823A1,CC(C)(C)OC(=O)N1CCNCC1.ClC[C@H]1CO1>>CC(C)(C)OC(=O)N1CCN(C[C@@H](O)CCl)CC1,,CO,,O=S(=O)([O-])[O-].[Mg+2],,test
US06218376B1,CCc1ccc2c(c1)CCc1sc(C)nc1C2(O)c1cn(Cc2cccc(C(=O)OC)c2)c(=O)[nH]c1=O>>CCc1ccc2c(c1)C=Cc1sc(C)nc1C2c1cn(Cc2cccc(C(=O)OC)c2)c(=O)[nH]c1=O,,CC(=O)O,,,,test
US20130267510A1,CC[C@@](C)(NC(=O)OC(C)(C)C)C(=O)Nc1cnc(Oc2cccc3c2C(C)CCO3)nc1>>CC[C@](C)(N)C(=O)Nc1cnc(Oc2cccc3c2C(C)CCO3)nc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110034445A1,Cc1nocc1C(=O)c1cccs1.NO>>Cc1nocc1C(=NO)c1cccs1,,c1ccncc1,,Cl,,test
US20150080364A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2cccc(Cl)c2)CC1>>O=C(c1cccc(Cl)c1)N1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120196845A1,CN=C=O.O=c1c2cn(CC3CCNCC3)c3ccccc3c-2nn1-c1ccccc1F>>CNC(=O)N1CCC(Cn2cc3c(=O)n(-c4ccccc4F)nc-3c3ccccc32)CC1,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US20130005707A1,CC(C)(C)C(=O)Nc1cccc(C(=O)C2CCOC2)n1>>CC(C)(C)C(=O)Nc1cccc(C(O)C2CCOC2)n1,,CCO,,[BH4-].[Na+],,test
US20090137561A1,COC(=O)c1ccc(-c2cc(OC)ccc2F)c(OC2CCCCO2)c1>>COc1ccc(F)c(-c2ccc(CO)cc2OC2CCCCO2)c1,,C1CCOC1,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060173043A1,COC(=O)CC1=CCCN(Cc2ccc(OC)cc2OC)C1=O>>COc1ccc(CN2CCC=C(CC(=O)O)C2=O)c(OC)c1,,O=C(O)C(F)(F)F,,[Li+].[OH-],,test
US20070104644A1,COC(=O)CCN(C1(C(=O)NOCc2ccccc2)CCCC1)S(=O)(=O)c1ccc(-c2ccc(F)cc2)cc1>>COC(=O)CCN(C1(C(=O)NO)CCCC1)S(=O)(=O)c1ccc(-c2ccc(F)cc2)cc1,[Pd],CO,,,,test
US05723450,CC(C)(C)c1ccc(OCCO)cc1.COc1c(Cl)ccnc1C>>COc1c(OCCOc2ccc(C(C)(C)C)cc2)ccnc1C,,CS(C)=O,,[H-].[Na+],[Cl-].[NH4+],test
US03944666,CCCCO.CCCCOP(=O)(Cl)c1ccccc1.ClP(Cl)c1ccccc1>>CCCCOP(OCCCC)c1ccccc1,,CCOCC,,,,test
US05574016,CCOC(=O)C=CC=Cc1ccc(C(=N)N)cc1.Cl>>CCOC(=O)CCCCc1ccc(C(=N)N)cc1.Cl,[Pd],CCO,,,,test
US20100280018A1,CC(=O)Cl.CNC1CCN(C(=O)OC(C)(C)C)CC1>>CC(=O)N(C)C1CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,,,test
US20100016401A1,CC(=O)C(C)Cl.COC(=O)c1cccc(O)c1>>CC(=O)C(C)Oc1cccc(C(=O)O)c1,,CC(C)=O,CCOCC,O,O=C([O-])[O-].[K+].[K+],test
US20020120011A1,Nc1cccc(N(Cc2cccc(OC(F)(F)C(F)F)c2)CC(O)C(F)(F)F)c1.O=S(=O)(Cl)c1ccc(F)cc1>>O=S(=O)(Nc1cccc(N(Cc2cccc(OC(F)(F)C(F)F)c2)CC(O)C(F)(F)F)c1)c1ccc(F)cc1,,ClCCl,,CCN(CC)CC,,test
US20060089364A1,Clc1cc(-c2ccccc2)ccn1.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1ccc(-c2ccccc2)cc1Cl,,ClCCl,,,,test
US20060258721A1,CC(C)(C)OC(=O)N1CCC(c2c[nH]c3ccc(N)cc23)CC1.CSC(=N)c1cccs1>>CC(C)(C)OC(=O)N1CCC(c2c[nH]c3ccc(NC(=N)c4cccs4)cc23)CC1,,CCO,,I,,test
US20070208062A1,Brc1ccc(C2=NO[C@H](COCC3CO3)C2)nc1.CNC>>CN(C)CC(O)COC[C@@H]1CC(c2ccc(Br)cn2)=NO1,,C1CCOC1,CC(C)O,,,test
US04659853,CCCCOCCCN.CCOC(=O)N=C=S>>CCCCOCCCNC(=S)NC(=O)OCC,,ClCCl,,,,test
US20160002224A1,C[Si](C)(C)CCOCn1c(Cl)cc2nc(-c3ccc(C4(CO)CC4)cc3)c(Cl)cc21.O[C@@H]1CO[C@@H]2[C@H](O)CO[C@H]12>>C[Si](C)(C)CCOCn1c(O[C@@H]2CO[C@@H]3[C@H](O)CO[C@H]23)cc2nc(-c3ccc(C4(CO)CC4)cc3)c(Cl)cc21,,CCOC(C)=O,CS(C)=O,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US20100267666A1,CI.N#CC1CCSCC1>>CC1(C#N)CCSCC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20160168156A1,COc1ncc(F)cc1C#CCCN>>COc1ncc(F)cc1C1=NCCC1,Cl[Pd]Cl,CC#N,O,,,test
US20150203505A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1[nH]c2ccc(OC)cc2c1CC[N+](=O)[O-]>>CCOC(=O)c1[nH]c2ccc(OC)cc2c1CCNC(=O)OC(C)(C)C,[Ni],C1CCOC1,,,,test
US20140081017A1,CCN(CC)S(F)(F)F.COC(=O)Cc1ccc(CCCC(O)c2ccccc2)cc1>>COC(=O)Cc1ccc(CCCC(F)c2ccccc2)cc1,,ClCCl,,,,test
US20080004309A1,CCOC(=O)c1ncc2c(c1O)c1ccccc1n2-c1ccccc1.O=C1CCC(=O)N1Br>>CCOC(=O)c1nc(Br)c2c(c1O)c1ccccc1n2-c1ccccc1,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20100204470A1,C[Si](C)(C)Cl.O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1>>Cl.O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1,,CCCCO,,,,test
US04822730,CCCCCCCCOc1ccc(C(C)(C)CC(C)(C)C)cc1.O=S(=O)(O)Cl>>CCCCCCCCOc1ccc(C(C)(C)CC(C)(C)C)cc1S(=O)(=O)Cl,,ClCCl,,O=P(Cl)(Cl)Cl,,test
US20080045526A1,COC=Cc1ccc2c(n1)COC2=C1C(=O)Nc2ccc(F)cc21>>COCCc1ccc2c(n1)COC2=C1C(=O)Nc2ccc(F)cc21,[Pd],CO,,,,test
US20100152168A1,C=O.CN1CCC(NC[C@H]2CCN(C(=O)OC(C)(C)C)C2)CC1>>CN1CCC(N(C)C[C@H]2CCN(C(=O)OC(C)(C)C)C2)CC1,,C1CCOC1,,,,test
US05273852,C[Si](C)(C)C[Mg]Cl.C[Si](Cl)(Cl)Cl>>C[Si](C)(C)C[Si](C)(Cl)Cl,,CCCCCC,,CCOCC,,test
US20050101521A1,O=Cc1ccc(Oc2ccc(Cl)nn2)cc1>>OCc1ccc(Oc2ccc(Cl)nn2)cc1,,CO,,O,[BH4-].[Na+],test
US05629325,CN1CCC[C@H]1COc1cncc(Br)c1.OB(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CN1CCC[C@H]1COc1cncc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20140249126A1,CCOC(=O)c1cn(CC)c2c(F)c(OC)c(OC)cc2c1=O>>CCn1cc(C(=O)O)c(=O)c2cc(O)c(O)c(F)c21,,CCO,ClCCl,BrB(Br)Br,,test
US05952386,NCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl.O=C(Cl)c1ccc(Cl)cc1>>O=C(NCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl)c1ccc(Cl)cc1,,ClCCl,,CCN(CC)CC,,test
US20030149027A1,CC(C)(C)OC(=O)NCc1ccc(Nc2ccccc2N)cc1.O=Cc1ccc(Br)cc1>>CC(C)(C)OC(=O)NCc1ccc(Nc2ccccc2NCc2ccc(Br)cc2)cc1,,CO,O,CC(=O)O,[BH3-]C#N.[Na+],test
US06933295B2,CC(C)(C)OC(=O)NCc1cccc(CN2C(=O)c3cccc(NC(=O)c4ccc(Cl)s4)c3C2O)c1>>NCc1cccc(CN2Cc3c(NC(=O)c4ccc(Cl)s4)cccc3C2=O)c1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20120190677A1,CS(N)(=O)=O.Cc1ccc(N2CCN(c3cncc(C4CC(C)(C)c5cc(C(=O)O)ccc5N4)c3)CC2)c(C)c1>>Cc1ccc(N2CCN(c3cncc(C4CC(C)(C)c5cc(C(=O)NS(C)(=O)=O)ccc5N4)c3)CC2)c(C)c1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20110079753A1,C=CC1CCC(C2CCC(c3ccc(C4CCC(CCCCC)CC4)cc3F)CC2)CC1>>CCCCCC1CCC(c2ccc(C3CCC(C4CCC(CC)CC4)CC3)c(F)c2)CC1,[Pd],Cc1ccccc1,,[H][H],,test
US20100113462A1,CCOC(=O)C1(N)Cc2c(C)sc(C)c2C1.Cc1cccc(C(=O)O)c1OC(C)C>>CCOC(=O)C1(NC(=O)c2cccc(C)c2OC(C)C)Cc2c(C)sc(C)c2C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040176361A1,Br.O=C(OCc1ccccc1)N1CCC(c2cc3ccccc3c(=O)[nH]2)CC1>>Br.O=c1[nH]c(C2CCNCC2)cc2ccccc12,,CC(=O)O,ClC(Cl)Cl,,,test
US20100041713A1,CC(C)(C)OC(=O)COc1cc(-c2ccccc2)cc2c1CCCC2=O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=C1CCCc2c(OS(=O)(=O)C(F)(F)F)cc(OS(=O)(=O)C(F)(F)F)cc21,,ClCCl,O,CCN(C(C)C)C(C)C,,test
US20060020146A1,COc1ccc(COC(=O)NN)cc1.Cc1c(C(=O)Cl)ccc2c1OCCO2>>COc1ccc(COC(=O)NNC(=O)c2ccc3c(c2C)OCCO3)cc1,,ClCCl,O,O=C([O-])[O-].[K+].[K+],,test
US20080293720A1,COC(=O)c1ccccc1O.O=[N+]([O-])c1cc(Cl)cnc1Cl>>COC(=O)c1ccccc1Oc1ncc(Cl)cc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140163025A1,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5ccc(CN6CCOCC6)cc5C#N)ccc(F)c43)ccc21>>N#Cc1cc(CN2CCOCC2)ccc1Oc1ccc(F)c2c1CC[C@H]2Oc1ccc2c(c1)OC[C@H]2CC(=O)O,,CCO,,[K+].[OH-],,test
US03935261,C=[N+]=[N-].CCCCCC(O)C=CC1CCC(O)C1CCCCCCC(=O)O>>CCCCCC(O)C=CC1CCC(O)C1CCCCCCC(=O)OC,,CCOCC,,,,test
US20100210577A1,NC1CCCC(C(=O)O)C1.O=C(O)CCl.S=C=S>>O=C(O)C1CCCC(N2C(=O)CSC2=S)C1,,O,,[K+].[OH-],,test
US06057358,COc1ccc(CCN(CCOc2ccc([N+](=O)[O-])cc2-n2cccc2)C(C)C)cc1OC.CS(=O)(=O)Cl>>COc1ccc(CCN(CCOc2ccc(NS(C)(=O)=O)cc2-n2cccc2)C(C)C)cc1OC.Cl,[Pd],CCOC(C)=O,CO,O,[H][H],test
US20130210818A1,COc1cc(-c2nc(-c3ccc(F)cc3)oc2Br)cnc1N.OB(O)c1ccncc1>>COc1cc(-c2nc(-c3ccc(F)cc3)oc2-c2ccncc2)cnc1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US06093732,CCOC=C(C(=O)OCC)C(=O)OCC.Nc1cc(C(F)(F)F)ccc1Cl>>CCOC(=O)C(=CN)C(=O)OCC,,c1ccc(Oc2ccccc2)cc1,,,,test
US20070264299A1,CN.Cc1cc(C#N)cc2c(=O)oc(-c3cc(Cl)nn3-c3ncccc3Cl)nc12>>CNC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(Cl)nn1-c1ncccc1Cl,,C1CCOC1,,,,test
US20100331315A1,O=C1CSC(=S)N1.O=Cc1ccc(-c2ccccc2C(=O)O)o1>>O=C1NC(=S)SC1=Cc1ccc(-c2ccccc2C(=O)O)o1,,CCO,,C1CCNCC1,,test
US04387158,CC(=O)OCCC(C)CCC=C(C)C.Oc1cccc(O)c1>>CC(=O)OCCC(C)CCCC(C)(C)c1ccc(O)cc1O,,CCOCC,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04742078,CC(=O)OC1C=CC(=O)C(C(C)C)O1.CCCCCCCCCCCCCCCCO>>CCCCCCCCCCCCCCCCOC1C=CC(=O)C(C(C)C)O1,,CCOCC,,,,test
US20100173886A1,Cc1ncc(Oc2ccc(C#N)cn2)c2ccccc12.OO>>Cc1ncc(Oc2ccc(C(N)=O)cn2)c2ccccc12,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US04898867,CCOC(=O)CBr.Cc1sc2[nH]c(=O)n(Cc3ccc(Cl)cc3)c(=O)c2c1C>>CCOC(=O)Cn1c(=O)n(Cc2ccc(Cl)cc2)c(=O)c2c(C)c(C)sc21,,CN(C)C=O,,[H-].[Na+],,test
US20050137236A1,CC(=O)Nc1ccc([C@H](COS(=O)(=O)c2ccc(C)cc2)O[Si](C)(C)C(C)(C)C)cn1.NCCc1ccc(Br)cc1>>CC(=O)Nc1ccc([C@H](CNCCc2ccc(Br)cc2)O[Si](C)(C)C(C)(C)C)cn1,,CCOC(C)=O,O,CCN(C(C)C)C(C)C,CS(C)=O,test
US20150064242A1,CCCCC/C=C\CCCBr.CCCCC/C=C\CCCC(C=O)CCC/C=C\CCCCC>>CCCCC/C=C\CCCC(O)C(CCC/C=C\CCCCC)CCC/C=C\CCCCC,,C1CCOC1,,Cl,[Mg],test
US20040053942A1,CC(=O)OC(C)=O.Fc1ccc(-c2cc3ccccn3n2)cc1>>CC(=O)c1c(-c2ccc(F)cc2)nn2ccccc12,O=S(=O)(O)O,,,[Na+].[OH-],,test
US04569994,Cc1cc(O)c2c3c(c(=O)oc2c1)CCCC3.ClCC1CO1>>Cc1cc(OCC2CO2)c2c3c(c(=O)oc2c1)CCCC3,,CS(C)=O,O,[Na+].[OH-],,test
US20100081680A1,CCOC(=O)C1CC2CC(=O)CC(C1)N2S(=O)(=O)c1ccc(Cl)cc1.OCCO>>CCOC(=O)C1CC2CC3(CC(C1)N2S(=O)(=O)c1ccc(Cl)cc1)OCCO3,,ClCCl,,,,test
US20100216814A1,CC(=CBr)c1ccc(Cl)c(Cl)c1.CN1CCc2[nH]c3ccc(Cl)cc3c2C1>>C/C(=C\n1c2c(c3cc(Cl)ccc31)CN(C)CC2)c1ccc(Cl)c(Cl)c1,[Cu]I,CN(C)C=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20110046169A1,CCOC=C(C(=O)OCC)C(=O)OCC.COc1ccccc1NN>>CCOC(=O)c1c[nH]n(-c2ccccc2OC)c1=O,,O,,Cl,O=C([O-])[O-].[K+].[K+],test
US07179823B1,BrCCBr.CCOC(=O)CCc1cn(Cc2ccc(O)cc2)nc1-c1ccccc1>>CCOC(=O)CCc1cn(Cc2ccc(OCCBr)cc2)nc1-c1ccccc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20110028509A1,O=C(O)C1(c2ccccc2)CC1.O=S(Cl)Cl>>O=C(Cl)C1(c2ccccc2)CC1,CN(C)C=O,ClCCl,,,,test
US20030191160A1,N#Cc1cccc2c1nc(-c1c(F)cccc1F)n2Cc1c(F)cccc1F.OO>>NC(=O)c1cccc2c1nc(-c1c(F)cccc1F)n2Cc1c(F)cccc1F,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20120165343A1,COC(=O)c1ccc(N(C(=O)OC(C)(C)C)C(CCC(F)(F)F)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2)nc1>>COC(=O)c1ccc(NC(CCC(F)(F)F)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2)nc1,,ClCCl,,CCOCC,Cl,test
US20110112096A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.Nc1ccc(Br)c2ccccc12>>CC(C)(C)OC(=O)N1CC=C(c2ccc(N)c3ccccc23)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20080009530A1,CCOC(=O)/C=C/c1ccc(OCOC)c(C)c1OCc1ccc(Cl)cc1Cl>>CCOC(=O)/C=C/c1ccc(O)c(C)c1OCc1ccc(Cl)cc1Cl,,CC(C)=O,,Cl,[Na+].[OH-],test
US04006145,CC(=O)O.N#CCc1cc([N+](=O)[O-])ccc1Sc1ccccc1>>O=C(O)Cc1ccccc1,,CC(=O)O,,O,O=S(=O)(O)O,test
US20100075952A1,CC(=O)OCC(=O)Nc1cc2c(cc1F)CC(=O)N2>>O=C(CO)Nc1cc2c(cc1F)CC(=O)N2,,CO,,O,[Na+].[OH-],test
US20110144091A1,NC1(C(=O)N[C@@H]2CCc3ccccc3-n3ccnc32)CC1.O=C(O)c1ccc(Cl)cc1>>O=C(NC1(C(=O)N[C@@H]2CCc3ccccc3-n3ccnc32)CC1)c1ccc(Cl)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100305113A1,CCOc1ccc(-c2ccc3nc(C)c(Br)n3n2)cc1OC.OB(O)c1ccc(O)nc1>>CCOc1ccc(-c2ccc3nc(C)c(-c4ccc(O)nc4)n3n2)cc1OC,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070142446A1,O=S(=O)(c1ccccc1)n1cc(-c2ccc(CN3CCCC3)s2)c2cccc(F)c21>>Fc1cccc2c(-c3ccc(CN4CCCC4)s3)c[nH]c12,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US04110445,N#CBr.NC(=O)CNc1ccccc1>>N=C1CN(c2ccccc2)C(=N)O1,,CCO,,O=C([O-])O.[K+],,test
US20130053369A1,CCN(c1ccc(C(=O)OC)cc1)S(=O)(=O)c1cccc(C(=O)Nc2sc3c(c2C(=O)Nc2ccc(CCc4ccc(C(=O)OC)cc4)cc2)CCCC3)c1>>CCN(c1ccc(C(=O)O)cc1)S(=O)(=O)c1cccc(C(=O)Nc2sc3c(c2C(=O)Nc2ccc(CCc4ccc(C(=O)O)cc4)cc2)CCCC3)c1,,CO,,[Na+].[OH-],,test
US04002660,CCOC(=O)CC(O)c1ccccc1>>O=C(O)CC(O)c1ccccc1,,CCO,,[K+].[OH-],,test
US06867200B1,CC(=O)c1cc(CCl)ccc1O.O=C1CCC(=O)N1Br>>CC(=O)c1cc(CCl)cc(Br)c1O,,CN(C)C=O,,,,test
US20100256098A1,NCCCO.O=C(Cl)OCc1ccccc1>>CCC(N)(O)C(=O)OCc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20140094459A1,CCOC(=O)C(C)(C)Br.NC1CC1>>CCOC(=O)C(C)(C)NC1CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070191309A1,COc1ccc2c(c1)C(=O)N1CCC(OCCCCCCCCCCCCOC3CCN4C(=O)c5cc(OC)ccc5N(C(=O)OC(C)(C)C)[C@@H](OC5CCCCO5)[C@H]34)[C@H]1[C@H](OC1CCCCO1)N2C(=O)OC(C)(C)C>>COc1ccc2c(c1)C(=O)N1CCC(OCCCCCCCCCCCCOC3CCN4C(=O)c5cc(OC)ccc5N=C[C@@H]34)[C@@H]1C=N2,,CO,ClC(Cl)Cl,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20030162764A1,C1CNCCN1.CC(=O)NCCNc1cc(Cl)nc(-c2ccc(Cl)cc2)n1>>CC(=O)NCCNc1cc(N2CCNCC2)nc(-c2ccc(Cl)cc2)n1,,CS(C)=O,,O=C([O-])O.[Na+],,test
US05192760,CCOC(=O)Nc1ccc2c(c1)N(C(=O)C(C)Br)c1ccccc1C=C2.CN>>CCOC(=O)Nc1ccc2c(c1)N(C(=O)C(C)NC)c1ccccc1C=C2,,CCO,,,,test
US20120028958A1,C#C[Si](C)(C)C.CCc1nc(N)ccc1I>>CCc1nc(N)ccc1C#C[Si](C)(C)C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,,CCN(CC)CC,,test
US20060183762A1,CC(C)(C)OC(=O)N1CCC2CN(Cc3ccccc3)CC2C1>>CC(C)(C)OC(=O)N1CCC2CNCC2C1,[Pd],CO,,[H][H],,test
US20130210768A1,CC(C)COC(=O)Cl.Cn1c(=O)n(CC(C)(C)C)c2ccc(-c3cccc(CN)c3)nc21>>CC(C)COC(=O)NCc1cccc(-c2ccc3c(n2)n(C)c(=O)n3CC(C)(C)C)c1,,C1CCOC1,CO,CCN(C(C)C)C(C)C,,test
US20100137425A1,O=c1c(Br)coc2ccccc12.OB(O)c1ccc(F)cc1>>O=c1c(-c2ccc(F)cc2)coc2ccccc12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,C1CCOC1,O=C([O-])[O-].[K+].[K+],test
US20120115845A1,COC(=O)c1cc(-c2cncs2)ccc1Cl>>O=C(O)c1cc(-c2cncs2)ccc1Cl,,CO,,Cl,[Na+].[OH-],test
US20080058389A1,CC(O)c1ccccc1[N+](=O)[O-].CS(=O)(=O)Cl>>CC(Cl)c1ccccc1[N+](=O)[O-],,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20040067955A1,CC(C)n1nc(-c2cc(C(N)=O)c(Cl)nc2-c2ccccc2)ccc1=O>>CC(C)n1nc(-c2cc(C(N)=O)cnc2-c2ccccc2)ccc1=O,[Pd],CO,,O=C[O-].[NH4+],,test
US03931206,CCOC(=O)COc1cccnc1.COP(C)(=O)OC>>COP(=O)(CC(=O)COc1cccnc1)OC,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US20100063050A1,COC(=O)C(N)C(=O)OC.O=C(Cl)c1ccc(Br)cc1>>COC(=O)C(NC(=O)c1ccc(Br)cc1)C(=O)OC,,O,,Cl,ClCCl,test
US20080312316A1,CC(C)c1oc2c(O)c(N)ccc2c(=O)c1-c1ccc(Cl)cc1.O=C(Br)CBr>>CC(C)c1oc2c3c(ccc2c(=O)c1-c1ccc(Cl)cc1)NC(=O)CO3,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20120015964A1,CO.COc1cccc(-n2c(C(C)Nc3ncnc4c3ncn4COCC[Si](C)(C)C)nc3cccc(C)c3c2=O)c1.Cc1cccc2nc(C(C)Nc3ncnc4[nH]cnc34)n(-c3cccc(O)c3)c(=O)c12>>COCCOc1cccc(-n2c(C(C)Nc3ncnc4[nH]cnc34)nc3cccc(C)c3c2=O)c1,,CO,,Cl,,test
US04524073,Cc1ccc(S(=O)(=O)OCCCC(C)(C)[N+](=O)[O-])cc1.NCc1ccccc1>>CC(C)(CCCNCc1ccccc1)[N+](=O)[O-],,CCN(CC)CC,,,,test
US04762835,BrBr.O=Cc1ccc(F)cc1>>O=Cc1ccc(F)c(Br)c1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US05688803,Cl.O=c1[nH]nc2c3cc([N+](=O)[O-])c(Cl)cc3[nH]c(=O)n12>>Cl.Nc1cc2c(cc1Cl)[nH]c(=O)n1c(=O)[nH]nc21,,Cl,,Cl[Sn]Cl,,test
US20150258074A1,CNC(=O)Cl.COc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(Cl)nc(CO)c12>>CNC(=O)OCc1nc(Cl)cc2c1c(OC)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040147729A1,CC(=O)OC[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.CSc1ccc(Cc2c(C(F)(F)F)[nH][nH]c2=O)cc1>>CSc1ccc(Cc2c(O[C@@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)n[nH]c2C(F)(F)F)cc1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20150011461A1,Cn1cc(Br)cc(N)c1=O.O=C(O)C1CC1>>Cn1cc(Br)cc(NC(=O)C2CC2)c1=O,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130178469A1,COC(=O)c1nc2c(NC(C)=O)cc(N3CCOCC3)cn2c(=O)c1O.NCc1ccc(F)cc1>>CC(=O)Nc1cc(N2CCOCC2)cn2c(=O)c(O)c(C(=O)NCc3ccc(F)cc3)nc12,,CO,,,,test
US20110237791A1,CCc1ccc(/C(=C/[C@H]2CCC(=O)N2Cc2ccc(OC)cc2OC)c2ccc(C(C)(C)C)cc2)nc1OC>>CCc1ccc(/C(=C/[C@H]2CCC(=O)N2Cc2ccc(OC)cc2OC)c2ccc(C(C)(C)C)cc2)[nH]c1=O,,C1COCCO1,,Br,O,test
US20090062366A1,COC(=O)c1ccccc1OC(=O)Oc1ccc([N+](=O)[O-])cc1.C[C@H](c1cccc2ccccc12)N(C[C@H]1CNC[C@@H]1c1ccccc1)C(=O)OC(C)(C)C>>COC(=O)c1ccccc1OC(=O)NN1C[C@@H](CN(C(=O)OC(C)(C)C)[C@H](C)c2cccc3ccccc23)[C@@H](c2ccccc2)C1,,CCOC(C)=O,,CC#N,CCN(CC)CC,test
US20090012063A1,CC(C)(C)OC(=O)N1CCC(N2CCC[C@H]2COC(=O)c2ccccc2)CC1>>O=C(OC[C@@H]1CCCN1C1CCNCC1)c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],test
US20130310357A1,CC(C)(C)OC(=O)N1CC=C(c2ccc(C(=O)[O-])nc2)CC1.CO>>COC(=O)c1ccc(C2CCN(C(=O)OC(C)(C)C)CC2)cn1,[Pd],,,[H][H],,test
US20160222022A1,COC(=O)c1ccc(CBr)c(Br)c1.NC(CO)c1ccccc1C(F)(F)F>>COC(=O)c1ccc(CNC(CO)c2ccccc2C(F)(F)F)c(Br)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20020156296A1,CC(=O)Oc1c(C(C)(C)C)cc(O)c(C=O)c1C.CC(C)[Mg]Br>>CC(=O)Oc1c(C(C)(C)C)cc(O)c(C(O)C(C)C)c1C,,C1CCOC1,,,,test
US04093631,CC(C)N.CC1(C)CC(c2ccccc2)c2ccc(OCC3CO3)cc2O1>>CC(C)NCC(O)COc1ccc2c(c1)OC(C)(C)CC2c1ccccc1,,CCO,,,,test
US04962206,BrBr.O=C1OC(=O)c2cc(Cl)ccc21>>O=C1OC(=O)c2cc(Br)ccc21,[Fe],Clc1ccccc1,,,,test
US20140275172A1,C#CC.O=Cc1cc(I)cc(I)c1O.c1ccncc1>>CC#Cc1cc(C=O)c2oc(C)cc2c1,,CCOC(C)=O,,,,test
US20140155373A1,Nc1ccccc1.O=Cc1cccc(C(=O)N2CCS[C@H]2C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)c1>>O=C(O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1)[C@@H]1SCCN1C(=O)c1cccc(CNc2ccccc2)c1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140194431A1,CC(C)N1CCn2c(Cc3ccc(Cl)cc3-c3ccc(F)cc3)nc(=O)c(OCc3ccccc3)c2C1=O>>CC(C)N1CCN2C(Cc3ccc(Cl)cc3-c3ccc(F)cc3)=NC(O)=C(O)C2=C1O,,CC(=O)O,,O=S(=O)(O)O,,test
US20020010183A1,CN(C)C=O.COc1ccc(C2NCCc3c2[nH]c2ccccc32)cc1OC>>COc1ccc(C2NCc3c2[nH]c2ccccc2c3=O)cc1OC,,CN(C)C=O,,Cl,CC(C)(C)[O-].[K+],test
US04891159,ClCC1CO1.O=S([O-])S(=O)(=O)[O-].[Na+]>>O=S(=O)([O-])CC(O)CCl.[Na+],,O,,[Na+].[OH-],,test
US20130156732A1,COC[C@H]1C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1.C[C@H]1CC[C@@H](C(=O)OCC(=O)c2ccc3c(c2)COc2cc4c(cc2-3)CCC(Br)C4=O)N1C(=O)OC(C)(C)C>>C[C@H]1CC[C@@H](C(=O)OCC(=O)c2ccc3c(c2)COc2cc4c(cc2-3)CCC(OC(=O)[C@@H]2CC[C@H](C)N2C(=O)OC(C)(C)C)C4=O)N1C(=O)OC(C)(C)C,,CC(C)=O,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050256137A1,COC(=O)[C@H](O)Cc1ccccc1.CS(=O)(=O)Cl>>COC(=O)[C@@H](Cc1ccccc1)OS(C)(=O)=O,,CCOCC,ClCCl,CCN(CC)CC,,test
US20130317057A1,NCc1cncc(F)c1.O=[N+]([O-])c1cc(F)c(F)cc1F>>Nc1ccccc1[N+](=O)[O-],,C1CCOC1,CCOC(C)=O,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20030096812A1,CC(C)(C)OC(=O)N1CCC(NC(=O)OCc2ccccc2)C(C)(C)C1>>CC1(C)CNCCC1NC(=O)OCc1ccccc1,,C1COCCO1,,Cl,,test
US20150183801A1,O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCCNCC2)c(Br)c1.OB(O)c1cccnc1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCCNCC2)c(-c2cccnc2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US05565483,COc1ccc(Cl)cc1C1C(=O)Nc2cc(C(F)(F)F)ccc21>>O=C1Nc2cc(C(F)(F)F)ccc2C1c1cc(Cl)ccc1O,,ClCCl,,BrB(Br)Br,,test
US20120196884A1,Fc1ccc(Br)nc1.c1cn[nH]c1>>Fc1ccc(-n2cccn2)nc1,[Cu]I,CS(C)=O,,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US20160229814A1,CC(CC(=O)O)CC(=O)Nc1ccc(C#N)c(Cl)c1.CCn1c(=O)c2nc(N)ccc2n(CC)c1=O>>CCn1c(=O)c2nc(NC(=O)CC(C)CC(=O)Nc3ccc(C#N)c(Cl)c3)ccc2n(CC)c1=O,,CCOC(C)=O,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US04752527,OCC(O)CO.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO.Oc1ccc(O)cc1.Oc1cccc(O)c1>>C=O.Oc1ccccc1.Oc1ccccc1Cc1ccccc1O,,OCC(O)CO,,,,test
US20020183314A1,CCOC(O)C(F)(F)F.CC[C@@H]1COc2c(ccc3nc(OC(C)C)cc(C(F)(F)F)c23)N1>>CC[C@@H]1COc2c(ccc3nc(OC(C)C)cc(C(F)(F)F)c23)N1CC(F)(F)F,,O=C(O)C(F)(F)F,,[BH3-]C#N.[Na+],,test
US04654362,C=CCBr.CCOC(=O)C1CCc2cc(O)ccc2O1>>C=CCOc1ccc2c(c1)CCC(C(=O)OCC)O2,,CN(C)C=O,,[H-].[Na+],,test
US20100298325A1,Fc1ccc(Oc2ccc(Cl)nc2)cc1F.Nc1cccc(OCCN2CCOCC2)c1>>Fc1ccc(Oc2ccc(Nc3cccc(OCCN4CCOCC4)c3)nc2)cc1F,,C1COCCO1,CCOC(C)=O,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20100273744A1,O=C(Nc1ccn(Cc2c(Cl)cccc2OCc2ccccc2)n1)c1c(F)cccc1F>>O=C(Nc1ccn(Cc2c(O)cccc2Cl)n1)c1c(F)cccc1F,[Pd],CCOC(C)=O,,,,test
US20080293694A1,COC(=O)c1cccc2[nH]cc(CC[N+](=O)[O-])c12>>O=C1NCCc2c[nH]c3cccc1c23,[Zn],CO,,Cl,,test
US05219860,CCCCCCI.c1ccc2c(c1)CCC21CCNCC1>>CCCCCCN1CCC2(CCc3ccccc32)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050192287A1,Nc1ccc(Cl)c(-c2ccncc2F)c1.S=C(Cl)Cl>>Fc1cnccc1-c1cc(N=C=S)ccc1Cl,,CC(C)=O,,O=C([O-])O.[Na+],,test
US04411901,Cl.Fc1ccc(C2(CCCCl)OCCCO2)cc1.c1ccc2c(N3CCNCC3)nsc2c1>>Cl.O=C(CCCN1CCN(c2nsc3ccccc23)CC1)c1ccc(F)cc1,,CC#N,CCO,[I-].[K+],,test
US20050288286A1,CCCCOC(=O)NS(=O)(=O)NCC(=O)OCC.COc1ccc(CO)cc1>>CCCCOC(=O)N(Cc1ccc(OC)cc1)S(=O)(=O)NCC(=O)OCC,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06380215B1,CC(C)(C)OC(=O)N1CCC(CCC(=O)N2CCCC(C(=O)NCCC(=O)O)C2)CC1.Cl>>Cl.O=C(O)CCNC(=O)C1CCCN(C(=O)CCC2CCNCC2)C1,,CCOC(C)=O,,,,test
US05008259,C=[N+]=[N-].CC(=O)O.COC(=O)c1cccc2c1NC(=O)C2=O>>COc1cccc2cc(O)c(=O)n(C(=O)O)c12,,CCOCC,,,,test
US20090137588A1,Cc1ccc([N+](=O)[O-])cc1Nc1cc(Nc2ccc(F)c(Cl)c2)ncn1>>Cc1ccc(N)cc1Nc1cc(Nc2ccc(F)c(Cl)c2)ncn1,[Fe],CC(=O)O,CO,,,test
US20150336949A1,Cc1ccc(S(=O)(=O)n2cc(-c3cnn(Cc4cccc(F)c4)c3)c3cc(-c4cccc(CC5CCNCC5)c4)cnc32)cc1.NC(=O)CCl>>Cc1ccc(S(=O)(=O)n2cc(-c3cnn(Cc4cccc(F)c4)c3)c3cc(-c4cccc(CC5CCN(CC(N)=O)CC5)c4)cnc32)cc1,,CC(C)=O,CCO,Cl,O=C([O-])O.[Na+],test
US20010018525A1,CCOC(=O)CCCCOc1c(-c2cccc(Cl)c2)cc(C(=O)NCCCCCCCCn2ccc3ccccc32)cc1-c1cccc(Cl)c1>>O=C(O)CCCCOc1c(-c2cccc(Cl)c2)cc(C(=O)NCCCCCCCCn2ccc3ccccc32)cc1-c1cccc(Cl)c1,,C1CCOC1,CO,[K+].[OH-],,test
US05641785,BrCc1ccccc1.C=C[C@@H]1OC(=O)N2c3ccc(O)cc3CC[C@H]12>>C=C[C@@H]1OC(=O)N2c3ccc(OCc4ccccc4)cc3CC[C@H]12,,CC#N,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100286088A1,CC#CCBr.NC(=O)c1ncn2c(=O)n(CO)nnc12>>CC#CCn1nnc2c(C(N)=O)ncn2c1=O,,CC#N,,C1CCC2=NCCCN2CC1,Cl,test
US03931209,C=O.CN(N)C(=O)Nc1nnc(C(F)(F)F)s1>>CN1NCN(c2nnc(C(F)(F)F)s2)C1=O,,CO,,[K+].[OH-],,test
US20150266848A1,COC(=O)[C@H](O)[C@@H](O)c1ccccc1Cl.COC(C)(C)OC>>COC(=O)[C@@H]1OC(C)(C)O[C@H]1c1ccccc1Cl,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100179168A1,Cc1ccc(-c2ccc(S(=O)(=O)Nc3cc(NC(=O)C(C)(C)NC(=O)OC(C)(C)C)ccc3F)cc2F)o1.Cl>>Cc1ccc(-c2ccc(S(=O)(=O)Nc3cc(NC(=O)C(C)(C)N)ccc3F)cc2F)o1.Cl,,C1COCCO1,,,,test
US20020161000A1,CI.O=C(O)c1c[nH]c(=O)c(C(=O)N(Cc2ccccc2)Cc2ccccc2)c1>>COc1ncc(C(=O)O)cc1C(=O)N(Cc1ccccc1)Cc1ccccc1,,CN(C)C=O,O,,,test
US20050032786A1,CSc1cc(-c2nc(=O)c3ccccc3s2)ccn1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1cc(-c2nc(=O)c3ccccc3s2)ccn1,,ClC(Cl)Cl,,,,test
US04333928,CC[C@@H]1C[C@H]2[C@@H]3CCC4=C(CCC(=O)C4)C3=CC[C@]2(C)[C@H]1OC(C)=O>>CC[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3C=C[C@]2(C)[C@H]1OC(C)=O,,Cc1ccccc1,ClCCl,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US05173485,C=CCON=C(C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(C[n+]3ccc4n3CCCN4)CS[C@H]12)c1nsc(N)n1.Cl>>C=CCON=C(C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(C[n+]3ccc4n3CCCN4)CS[C@H]12)c1nsc(N)n1.Cl,,O,,,,test
US20130225620A1,CN(C)C=O.Fc1cc(Br)c2cnn(C3CCCCO3)c2c1>>O=Cc1cc(F)cc2c1cnn2C1CCCCO1,,C1CCOC1,,[Li]CCCC,,test
US20130210768A1,CC(=O)c1ccc(C)c(-c2ccc3c(n2)n(C)c(=O)n3CC(C)(C)C)c1>>Cc1ccc([C@H](C)O)cc1-c1ccc2c(n1)n(C)c(=O)n2CC(C)(C)C,,CO,,[BH4-].[Na+],,test
US20070254925A1,CN.O=Cc1nc(NC(=O)c2c(F)cccc2F)sc1-c1cccc(C(F)(F)F)c1.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>Cn1cncc1-c1nc(NC(=O)c2c(F)cccc2F)sc1-c1cccc(C(F)(F)F)c1,,CC(=O)O,CCO,O=C([O-])[O-].[K+].[K+],,test
US20160083387A1,C=C1CC[C@H]2[C@H](CN)[C@@H]([C@@]3(C)CC[C@H](O[Si](C)(C)C(C)(C)C)C[C@@H]3CO[Si](C)(C)C(C)(C)C)CC[C@]12C.O=Cc1ccc2c(c1)OCO2>>C=C1CC[C@H]2[C@H](CNCc3ccc4c(c3)OCO4)[C@@H]([C@@]3(C)CC[C@H](O[Si](C)(C)C(C)(C)C)C[C@@H]3CO[Si](C)(C)C(C)(C)C)CC[C@]12C,,CO,O,[BH4-].[Na+],,test
US20030225108A1,CC(=O)N1CCC(/C(Cc2ccncn2)=N/NS(=O)(=O)c2ccc(C)cc2)CC1.O=C(Cl)c1ccc(Cl)cc1>>CC(=O)N1CCC(c2nn(S(=O)(=O)c3ccc(C)cc3)c(-c3ccc(Cl)cc3)c2-c2ccncn2)CC1,CN(C)c1ccncc1,CCN(CC)CC,,C1CCOC1,,test
US20120288492A1,CCOC(=O)c1nc(-c2ccc(N)cc2)nc(N2CCOCC2)c1OCC>>CCOc1c(CO)nc(-c2ccc(N)cc2)nc1N1CCOCC1,,CCO,,[BH4-].[Na+],,test
US04870063,CCCCC(Br)C(=O)OCC.NCCS>>CCCCC1SCCNC1=O,,CCO,,Cl,[K+].[OH-],test
US20110301170A1,CC(=O)CBr.Nc1cnccn1>>Cc1cn2ccncc2n1,,CCO,,,,test
US04007276,NC(=S)Nc1nc2n(n1)Cc1ccccc1-2.OO>>NC(=O)Nc1nc2n(n1)Cc1ccccc1-2,,[Na+],[OH-],Cl,,test
US20100010035A1,CCCc1nn(-c2ccccn2)c(=O)[nH]1.COCCOCN(c1nc(C)c(C)s1)S(=O)(=O)c1sccc1-c1ccc(COS(C)(=O)=O)cc1>>CCCc1nn(-c2ccccn2)c(=O)n1Cc1ccc(-c2ccsc2S(=O)(=O)N(COCCOC)c2nc(C)c(C)s2)cc1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20100305067A1,CCN=C=O.Nc1nc2cc(Br)cnc2s1>>CCNC(=O)Nc1nc2cc(Br)cnc2s1,,C1COCCO1,,,,test
US05712300,C=C(C)C1(CC(C)C)CCN(CC(=O)OCC)C1=O.CN>>C=C(C)C1(CC(C)C)CCN(CC(=O)NC)C1=O,,CCO,,,,test
US20070225494A1,O=C(O)c1ccccc1SSc1ccccc1C(=O)O.O=[N+]([O-])c1ccccc1Cl>>O=C(O)c1ccccc1Sc1ccccc1[N+](=O)[O-],[Zn],O,,[Na+].[OH-],,test
US20050143452A1,Cc1ccccc1-c1cc(F)cc2c1OC(CN=[N+]=[N-])C2>>Cc1ccccc1-c1cc(F)cc2c1OC(CN)C2,[Pd],,,,,test
US20120190677A1,CC1(C)CC(c2cccc(N3CCN(c4ccccc4F)CC3)c2)Nc2c(C(=O)O)cc(F)cc21.CS(N)(=O)=O>>CC1(C)CC(c2cccc(N3CCN(c4ccccc4F)CC3)c2)Nc2c(C(=O)NS(C)(=O)=O)cc(F)cc21,CN(C)c1ccncc1,ClCCl,,,,test
US20150266824A1,CCOC(=O)[C@@H]1CC[C@@H](n2ncc(C(=O)N(CC(=O)c3c(Cl)cncc3Cl)Cc3cc(F)cc(F)c3)c2C(F)F)CC1>>O=C(CN(Cc1cc(F)cc(F)c1)C(=O)c1cnn([C@@H]2CC[C@@H](C(=O)O)CC2)c1C(F)F)c1c(Cl)cncc1Cl,,C1COCCO1,,Cl,O,test
US20150252046A1,CCC(=O)N1CC2CN(C(=O)c3ccc(Br)cc3)CC2C1.OB(O)c1ccc2cnccc2c1>>CCC(=O)N1CC2CN(C(=O)c3ccc(-c4ccc5cnccc5c4)cc3)CC2C1,,C1COCCO1,,O=C(O)O,,test
US20030166639A1,CC(C)(C)OC(=O)Nc1cc(OCC(F)(F)F)c(C(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-c2ccncc2)c1>>O=C1CC(c2cccc(-c3ccncc3)c2)=Nc2cc(OCC(F)(F)F)c(C(F)(F)F)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05378689,CC(C)CN.C[C@@H]1C[C@@H]([C@H](CC2CCCCC2)NC(=O)OC(C)(C)C)OC1=O>>CC(C)CNC(=O)[C@H](C)C[C@H](O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C,,CO,,,,test
US05034417,CC(=O)c1ccc(NS(C)(=O)=O)c(Nc2ccc(F)cc2F)c1.CON>>CON=C(C)c1ccc(NS(C)(=O)=O)c(Nc2ccc(F)cc2F)c1,,CCO,,Cl,c1ccncc1,test
US20140275071A1,CC=O.Cn1c(=O)n(CCCO[Si](C)(C)C(C)(C)C)c(=O)c2c1nc(Br)n2Cc1ccc(Cl)cc1>>CC(O)c1nc2c(c(=O)n(CCCO[Si](C)(C)C(C)(C)C)c(=O)n2C)n1Cc1ccc(Cl)cc1,,C1CCOC1,O,[Li]CCCC,,test
US07001904B1,COc1cc2c(N=C(NCC(=O)OC(C)(C)C)Nc3c(C)cccc3C)ncnc2cc1OCC1CCN(C)CC1>>COc1cc2c(N=C(NCC(=O)O)Nc3c(C)cccc3C)ncnc2cc1OCC1CCN(C)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04436751,O=Cc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]>>O=[N+]([O-])c1ccc(CO)c([N+](=O)[O-])c1,,CCO,,[BH4-].[Na+],,test
US20150175557A1,CNC(=O)C1CCC(N)CC1.N#Cc1cnc(NCc2cnccc2C(F)(F)F)nc1Cl>>CNC(=O)[C@@H]1CC[C@H](Nc2nc(NCc3cnccc3C(F)(F)F)ncc2C#N)CC1,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20050096337A1,CC(C)(C)O.COC(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)nc1C.Cc1nc(-c2ccc(C(F)(F)F)cc2)ccc1C(=O)O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cc1nc(-c2ccc(C(F)(F)F)cc2)ccc1NC(=O)OC(C)(C)C,,CC(C)(C)O,,CCN(CC)CC,Cc1ccc(S(=O)(=O)O)cc1,test
US20020147342A1,CC#CCOc1ccc(SC(CCCCCC)C(=O)O)cc1.OO>>CC#CCOc1ccc([S@](=O)[C@@H](CCCCCC)C(=O)O)cc1,,CO,,,,test
US20080227834A1,CCCCN.N#Cc1ccc(CBr)cc1F>>CCCCNCc1ccc(C#N)c(F)c1,,CN(C)C=O,,,,test
US04263207,COC(=O)c1ccc2c(c1)Sc1ccccc1NC2=O.N>>N#Cc1ccc2c(c1)Sc1ccccc1NC2=O,,CO,,,,test
US20150239847A1,Nc1ccn(-c2ccccc2Cl)n1.O=C1CCC(=O)N1Cl>>Nc1nn(-c2ccccc2Cl)cc1Cl,,C1CCOC1,,,,test
US20070185171A1,CC1(C)CC(=O)Nc2cc(N)ccc21.O=C(O)c1cccnc1NCc1c[nH]c2ncccc12>>CC1(C)CC(=O)Nc2cc(NC(=O)c3cccnc3NCc3c[nH]c4ncccc34)ccc21,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20110034433A1,C=CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)NC1c1ccc(C#N)cc1S(=O)(=O)CC>>CCS(=O)(=O)c1cc(C#N)ccc1C1NC(=O)N(c2cccc(C(F)(F)F)c2)C(C)=C1C(=O)O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,C1COCCN1,,test
US20040116698A1,CCC(N)c1ccccc1.Cn1c(=O)c(Oc2ccccc2F)cc2cnc(S(C)(=O)=O)nc21>>CCC(Nc1ncc2cc(Oc3ccccc3F)c(=O)n(C)c2n1)c1ccccc1,,CN1CCCC1=O,,,,test
US05210092,CCCC(=O)N(Cc1ccc(-n2cc(Cl)cc2C#N)cc1)c1nccc(C)c1[N+](=O)[O-]>>CCCc1nc2c(C)ccnc2n1Cc1ccc(-n2cc(Cl)cc2C#N)cc1,[Fe],CCO,,CC(=O)O,,test
US20050107364A1,COC1=CC(=O)c2ccccc2C1(CCC(C)C)COC(=O)NC(C)C>>CC(C)CCC1(COC(=O)NC(C)C)C(=O)CC(=O)c2ccccc21,,CC#N,,C[Si](C)(C)I,,test
US03963717,CC(C)I.Nc1cccc2c1OCC2>>CC(C)Nc1cccc2c1OCC2,,CCN(CC)CC,,CO,,test
US20140024650A1,CS(=O)(=O)Cl.N[C@H]1CCOC[C@@H]1COc1cc(F)c(-n2cc(Cl)cn2)c(F)c1>>CS(=O)(=O)N[C@H]1CCOC[C@@H]1COc1cc(F)c(-n2cc(Cl)cn2)c(F)c1,,C1CCOC1,,CO,Cl,test
US20070254869A1,CCOC(=O)CCCN(c1ccccc1C(=O)OC)S(=O)(=O)c1ccc(C)cc1>>CCOC(=O)C1CCN(S(=O)(=O)c2ccc(C)cc2)c2ccccc2C1=O,,Cc1ccccc1,,CC(C)(C)[O-].[K+],,test
US20100081653A1,CN1CCN(C(=O)c2cnc(Cl)nc2C(F)(F)F)CC1.NC(=O)Cc1nc2ccccc2s1>>CN1CCN(C(=O)c2cnc(C(C(N)=O)=C3Nc4ccccc4S3)nc2C(F)(F)F)CC1.Cl,,C1CCOC1,,[H-].[Na+],,test
US05399580,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@H]1C=C[C@@H](CO)C1>>CC(C)(C)OC(=O)N[C@@H]1C=C[C@H](CO)C1,,C1COCCO1,O,O=C([O-])O.[Na+],,test
US20070117824A1,CC(C)(C)OC(=O)N1CC2(CCNCC2)C1.CC(C)(C)OC(=O)Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(Cl)nc1>>Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(N2CCC3(CC2)CNC3)nc1,,CS(C)=O,,CCN(CC)CC,,test
US20010031760A1,CCOC(=O)C1CCN(c2nc(NCc3ccc4c(c3)OCO4)c3cc(Cl)ccc3n2)CC1>>O=C(O)C1CCN(c2nc(NCc3ccc4c(c3)OCO4)c3cc(Cl)ccc3n2)CC1,,O,,CCO,[Na+].[OH-],test
US06627651B1,CCCOc1ccc(Oc2ccc3c(c2)C=C(C(=O)OC)CCS3(=O)=O)cc1>>CCCOc1ccc(Oc2ccc3c(c2)C=C(C(=O)O)CCS3(=O)=O)cc1,,C1CCOC1,CO,Cl,O=C([O-])[O-].[K+].[K+],test
US20050054590A1,CC(=O)OC[C@H]1O[C@@H](n2c(=O)sc3c(=O)[nH]c(N)nc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O.Cc1oc(=O)oc1CO>>CC(=O)OC[C@H]1O[C@@H](n2c(=O)sc3c(OCc4oc(=O)oc4C)nc(N)nc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020147160A1,C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1ccc2c(N)ncnc21.O=C1CCC(=O)N1Cl>>C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cc(Cl)c2c(N)ncnc21,,CN(C)C=O,,,,test
US20080182854A1,BrCc1cccc(CBr)n1.C1COCCN1>>BrCc1cccc(CN2CCOCC2)n1,,CCO,,,,test
US20080176919A1,CCN(CC)C(=S)Cl.N#Cc1cc(O)cc(Cl)c1>>CCN(CC)C(=S)Oc1cc(Cl)cc(C#N)c1,,CN1CCCC1=O,O,[H-].[Na+],,test
US20160093915A1,CCCCC(CC)C(=O)[O-].CCCCC(CC)C(=O)[O-].CCCCC(CC)C(=O)[O-].CCCCOCCO.Cc1ccccc1.[La+3]>>CCCCC(CC)C(=O)[O-].CCCCC(CC)C(=O)[O-].CCCCC(CC)C(=O)[O-].CCCCOCCO.Cc1ccccc1.[La+3],,Cc1ccccc1,,,,test
US20100016396A1,CCOP(=O)(CCOC(C)=O)OCC.COCOc1cc(Oc2c(C)c(C)nn2C)c(Cl)cc1C=O>>CCOC(=O)/C=C/c1cc(Cl)c(Oc2c(C)c(C)nn2C)cc1OCOC,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20130131042A1,CCOc1cc(C=O)c(Br)cc1C.Cc1cn[nH]c1>>CCOc1cc(C=O)c(-n2cc(C)cn2)cc1C,[Cu]I,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04701464,CO.OCc1c(F)c(F)nc(F)c1F>>COc1nc(F)c(F)c(CO)c1F,,CO,,O,C[O-].[Na+],test
US20100111900A1,CC1(C)OB(c2cccnc2OCc2ccccc2)OC1(C)C.CNC(=O)c1cc(OC)c(C(C)(C)C)cc1Br>>CNC(=O)c1cc(OC)c(C(C)(C)C)cc1-c1cccnc1OCc1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,ClCCl,O=C([O-])[O-].[Na+].[Na+],,test
US20070032530A1,Cc1cc(O)ccc1CCCCn1ccnn1.Cc1nc(-c2cccc(OC(F)(F)F)c2)ccc1CCl>>Cc1cc(OCc2ccc(-c3cccc(OC(F)(F)F)c3)nc2C)ccc1CCCCn1ccnn1,,CN(C)C=O,,O,[H-].[Na+],test
US20100069368A1,NN.O=C1OC(=O)C2=C1CC=CC2>>O=c1[nH][nH]c(=O)c2c1CC=CC2,,Cc1ccccc1,,O,,test
US20050153959A1,CCOC(=O)CC(Cc1cc(C)c2nn(COCC[Si](C)(C)C)cc2c1)c1cc(CC)ccn1>>CCc1ccnc(C(CC(=O)O)Cc2cc(C)c3nn(COCC[Si](C)(C)C)cc3c2)c1,,C1CCOC1,,[Li+].[OH-],,test
US20160002214A1,COc1ccc(C(=O)O)cc1.COc1ccc2[nH]c(-c3ccc(/C(N)=N/O)cc3)nc2c1>>COc1ccc(-c2nc(-c3ccc(-c4nc5cc(OC)ccc5[nH]4)cc3)no2)cc1,,CN(C)C=O,,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US20150126490A1,COC(=O)c1ccc(-c2nc(C3=CNCCC3)cnc2N)cc1F>>COC(=O)c1ccc(-c2nc(C3CCCNC3)cnc2N)cc1F,[Pd],CO,,,,test
US20150094467A1,N#Cc1ccc(Br)cc1N>>NCc1ccc(Br)cc1N,,C1CCOC1,,B,,test
US05157041,CC(C)(C)OC(=O)N[C@H]1CN(C(C)(C)C)[C@](C[C@@H](O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)(C(N)=O)C1.N#N>>CC(C)(C)OC(=O)N[C@H]1CN(C(C)(C)C)[C@](C[C@@H](O)[C@@H](N)Cc2ccccc2)(C(N)=O)C1.N#N,[Pd],CCO,,,,test
US05374454,c1ccc2cc3ccccc3cc2c1>>c1ccc2cc3ccccc3cc2c1,[Pd],,,CN(C)C=O,,test
US20050143415A1,CCOC(=O)C(=O)CC(C)(C)c1ccccc1.Cl[Mg]C1CCCC1>>CCOC(=O)C(O)(CC(C)(C)c1ccccc1)C1CCCC1,,C1CCOC1,,[Cl-].[NH4+],,test
US20090004185A1,CN1CCN(CCCN)CC1.Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(F)cc4)cc3)nc(Cl)nc2c1>>Cc1ccc2c(NCc3ccc(NC(=O)c4ccccc4)cc3)nc(NCCCN3CCN(C)CC3)nc2c1,,C1COCCO1,,,,test
US05216167,CCOc1cc(CC(=O)NC(C(=O)O)c2ccccc2N2CCCCC2)ccc1C(=O)OCc1ccccc1.CI>>CCOc1cc(CC(=O)NC(C(=O)OC)c2ccccc2N2CCCCC2)ccc1C(=O)OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05550130,Cl.O=C1c2ccccc2C(=O)N1CCN1CCN(c2n[nH]c3cc(F)ccc23)CC1>>Cl.O=C1c2ccccc2C(=O)N1CCN1CCN(c2n[nH]c3cc(F)ccc23)CC1,,CO,,CCOCC,,test
US04897490,CCOC(=O)CC(C)=O.Cc1cc(C(=C(C=CC=O)c2nnnn2C)c2ccc(F)c(C)c2)ccc1F>>CCOC(=O)CC(=O)CC(O)C=CC(=C(c1ccc(F)c(C)c1)c1ccc(F)c(C)c1)c1nnnn1C,,C1CCOC1,CCCCCC,[Li]CCCC,[H-].[Na+],test
US05959113,CC(C)c1cccc(C(C)C)c1Br.O=CN1CCCCC1>>CC(C)c1cccc(C(C)C)c1C=O,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US20070219210A1,COCNC(=O)c1ccc(OCc2ccccc2)cn1.[Li]C>>CC(=O)c1ccc(OCc2ccccc2)cn1,,C1CCOC1,CCOCC,CCOC(C)=O,O,test
US07074801B1,NC1CC1.O=C(O)c1ccc(-c2ncnc3ccc(Cl)cc23)cc1F>>O=C(NC1CC1)c1ccc(-c2ncnc3ccc(Cl)cc23)cc1F,,ClCCl,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20140171403A1,CN(CCC1CCN(C(=O)OC(C)(C)C)CC1)C(=O)c1c[nH]nn1>>CN(CCC1CCNCC1)C(=O)c1c[nH]nn1,,CCOC(C)=O,,C1COCCO1,Cl,test
US06469210B1,COC(=O)C(C)(NC(=O)C(C)c1ccc(Cl)cc1)C(C)C>>CC(C(=O)NC(C)(C(=O)O)C(C)C)c1ccc(Cl)cc1,,CS(C)=O,,Cl,[Na+].[OH-],test
US20090124656A1,CC1(C)CCNc2ccccc21.O=C(Br)CBr>>CC1(C)CCN(CCBr)c2ccccc21,,C1CCOC1,,CCN(CC)CC,,test
US20160221972A1,COC(=O)c1ccc(CBr)c(Br)c1.NCCO>>COC(=O)c1ccc(CNCCO)c(Br)c1,,CO,ClCCl,CC#N,O=C([O-])[O-].[K+].[K+],test
US04423213,ClP(Cl)(Cl)(Cl)Cl.O=C(OC(c1ccccc1)c1ccccc1)C1=C(CO)CS[C@@H]2C(N=Cc3ccccc3O)C(=O)N12>>O=C(OC(c1ccccc1)c1ccccc1)C1=C(CCl)CS[C@@H]2C(N=Cc3ccccc3O)C(=O)N12,,ClCCl,,c1ccncc1,,test
US20140024650A1,CCS(=O)(=O)N[C@@H]1CCC2(C[C@H]1COc1ccc(-n3cccn3)cc1)OCCO2>>CCS(=O)(=O)N[C@@H]1CCC(=O)C[C@H]1COc1ccc(-n2cccn2)cc1,,CC(C)=O,,Cl,,test
US04051145,Nc1ccccc1CC(F)(F)F.O=N[O-]>>FC(F)(F)c1n[nH]c2ccccc12,,O,,CC(=O)O,,test
US20050176751A1,CC(C)(C)OC(=O)N1CCC(c2cn(Cc3ccoc3)c3ncccc23)CC1>>c1cnc2c(c1)c(N1CCCCC1)cn2Cc1ccoc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20040023479A1,F[B-](F)(F)F.N#[O+].Nc1ccc(C=Cc2ccccc2)cc1>>F[B-](F)(F)F.N#[N+]c1ccc(C=Cc2ccccc2)cc1,,CC#N,,CCOCC,,test
US04789680,N#CCC(N)=O.[N-]=[N+]=NCc1ccccc1Cl>>NC(=O)c1nnn(Cc2ccccc2Cl)c1N,,CCO,,O,[Na],test
US20100233116A1,Cc1nc(N2CCN(c3ccccc3)C2=O)sc1C(=O)O.NCc1ccccc1>>Cc1nc(N2CCN(c3ccccc3)C2=O)sc1C(=O)NCc1ccccc1,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20140031360A1,Brc1cncc(C2CC2)n1.CC(C)(C)OC(=O)N1CCC[C@@H](Oc2cncc(-c3nn(C4CCCCO4)c4ccc(B5OC(C)(C)C(C)(C)O5)cc34)n2)C1>>CC(C)(C)OC(=O)N1CCC[C@@H](Oc2cncc(-c3nn(C4CCCCO4)c4ccc(-c5cncc(C6CC6)n5)cc34)n2)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US05057614,Cn1cc(C2=C(c3cccc4ccccc34)C(=O)OC2=O)c2ccccc21.N>>Cn1cc(C2=C(c3cccc4ccccc34)C(=O)NC2=O)c2ccccc21,,CN(C)C=O,,,,test
US20140005168A1,Cc1cncc(-c2cc3c(cn2)cnn3-c2cccc(C3CCN(C(=O)OC(C)(C)C)CC3)n2)n1>>Cc1cncc(-c2cc3c(cn2)cnn3-c2cccc(C3CCNCC3)n2)n1,,Cl,,C1COCCO1,,test
US20090286778A1,CI.Clc1ncc(Cl)c(Nc2cccc(OC3CCCCO3)c2)n1>>CN(c1cccc(OC2CCCCO2)c1)c1nc(Cl)ncc1Cl,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20040082577A1,C=Cc1nc(-c2ccccc2)c(CN(Cc2cccc(OCC)c2)Cc2ccc3c(c2)OCCO3)n1CCCC>>CCCCn1c(CC)nc(-c2ccccc2)c1CN(Cc1cccc(OCC)c1)Cc1ccc2c(c1)OCCO2,[Pd],CCOC(C)=O,,,,test
US20040147748A1,COC(C)(OC)c1cnc(N)cn1.CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)O)cc1Cl>>COC(C)(OC)c1cnc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(C)(=O)=O)c(Cl)c2)cn1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20100256188A1,CN(C)CCNc1ccc(C(=O)Nc2ccc(Br)cc2)cc1[N+](=O)[O-]>>CN(C)CCNc1ccc(C(=O)Nc2ccc(Br)cc2)cc1N,[Fe],CCO,,[Cl-].[NH4+],,test
US20040220415A1,CCOC(=O)CBr.COc1c(Br)cc(C=O)c(O)c1Br>>CCOC(=O)c1cc2cc(Br)c(OC)c(Br)c2o1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US08946697B1,Cc1ccc2c(n1)oc1c(B3OC(C)(C)C(C)(C)O3)cccc12.Clc1cc(-c2ccccc2)ccn1>>Cc1ccc2c(n1)oc1c(-c3cc(-c4ccccc4)ccn3)cccc12,,O,,COc1cccc(OC)c1-c1ccccc1P(C1CCCCC1)C1CCCCC1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US04223016,COC(=O)CNC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)[C@H](CCCNC(=N)N[N+](=O)[O-])NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1)[C@@H](C)OCc1ccccc1>>C[C@@H](OCc1ccccc1)[C@H](NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)[C@H](CCCNC(=N)N[N+](=O)[O-])NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)NCC(=O)O,,CN(C)C=O,CO,[Na+].[OH-],,test
US20150001471A1,Brc1cccc2c1[nH]c1ccccc12.Clc1nc(-c2ccccc2)nc(-c2ccccc2)n1>>Brc1cccc2c3ccccc3n(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)c12,,CN(C)C=O,,O,[H-].[Na+],test
US20070166705A1,CC(C)(C)[Si](C)(C)Cl.Nc1nc(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1I>>CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@H](n2cc(I)c(N)nc2=O)C[C@@H]1O,,CN(C)C=O,,c1c[nH]cn1,,test
US04665176,Nc1nc2c(c(=O)[nH]1)N=C(CNc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1)CN2>>Nc1nc2c(c(=O)[nH]1)NC(CNc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1)CN2,[Pt],,,,,test
US20120053201A1,COC(=O)c1ccc2c(n1)CCNC2.O=C=NCc1ccccc1>>COC(=O)c1ccc2c(n1)CCN(C(=O)NCc1ccccc1)C2,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20120041026A1,CC(C)=O.O=C(O)c1c(O)cccc1O>>CC1(C)OC(=O)c2c(O)cccc2O1,CN(C)c1ccncc1,COCCOC,,O=S(Cl)Cl,,test
US20100152207A1,CI.COC(=O)CCCc1ccccc1NC(=O)c1ccc(Cl)c(Br)c1>>COC(=O)CCCc1ccccc1N(C)C(=O)c1ccc(Cl)c(Br)c1,,CN(C)C=O,,[H-].[Na+],,test
US20090131472A1,CC(=N)NO.O=C(O)c1ccc(F)c(-c2c(=O)ccn3c(-c4ccc(F)cc4F)cccc23)c1>>Cc1noc(-c2ccc(F)c(-c3c(=O)ccn4c(-c5ccc(F)cc5F)cccc34)c2)n1,,CC#N,CCOC(C)=O,ClCCCl,On1nnc2ccccc21,test
US20080004302A1,CC(C)Oc1cc(Nc2ccnc(Cl)n2)[nH]n1.CC1(c2cc(CN)on2)COC1>>CC(C)Oc1cc(Nc2ccnc(NCc3cc(C4(C)COC4)no3)n2)[nH]n1,,COCCO,,CCN(C(C)C)C(C)C,,test
US20040162279A1,CC(Cl)OC(=O)Cl.CNCCN(C)C.C[C@H]1CN(Cc2ccccc2)C[C@@H](C)O1.O=Cc1cc([N+](=O)[O-])ccc1F>>CC[C@H]1CN(c2ccc([N+](=O)[O-])cc2C=O)C[C@@H](CC)O1,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])[O-].[K+].[K+],test
US20150214490A1,Clc1nc(-c2ccccc2)nc(-c2ccccc2)n1.O=[N+]([O-])c1ccncc1-c1cccc2c(-c3ccccc3)c[nH]c12>>O=[N+]([O-])c1ccncc1-c1cccc2c(-c3ccccc3)cn(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)c12,,CN(C)C=O,,[H-].[Na+],,test
US20100260710A1,COc1ccc(COc2cc(Cl)nc3c(Cl)c(OC)ccc23)cc1.FC(F)(F)c1cc[nH]n1>>COc1ccc(COc2cc(-n3ccc(C(F)(F)F)n3)nc3c(Cl)c(OC)ccc23)cc1,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20040058907A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1nnn[nH]1>>CC(C)(C)OC(=O)NCc1nnn[nH]1,,CO,O,[Na+].[OH-],,test
US20160200725A1,C=CC(=O)Cl.CCN(CCn1c(=O)c(-c2c(Cl)c(OC)cc(OC)c2Cl)cc2cnc(NC)nc21)C1CCNCC1>>C=CC(=O)N1CCC(N(CC)CCn2c(=O)c(-c3c(Cl)c(OC)cc(OC)c3Cl)cc3cnc(NC)nc32)CC1,,CO,ClCCl,,,test
US20110124665A1,CCOC(=O)/C=C/c1cccc(N)c1.COc1ccc(-c2c(-c3ccccc3)oc3ncnc(Cl)c23)cc1>>CCOC(=O)/C=C/c1cccc(Nc2ncnc3oc(-c4ccccc4)c(-c4ccc(OC)cc4)c23)c1,,ClCCl,,,,test
US20080119518A1,CI.COC(=O)Cc1cc(OC)ccc1OC>>COC(=O)C(C)c1cc(OC)ccc1OC,,C1CCOC1,,CCOCC,[H-].[Na+],test
US06326359B1,COC[C@H]1O[C@@H](n2cnc3c(NCCc4ccccc4)nc(C#N)nc32)[C@H](OC(=O)c2ccccc2)[C@@H]1OC(=O)c1ccccc1>>COC[C@H]1O[C@@H](n2cnc3c(NCCc4ccccc4)nc(C#N)nc32)[C@H](O)[C@@H]1O,,N,,,,test
US05302593,CN1CCNCC1.O=C1NC(=O)c2c(CCCCCCCCBr)cccc21>>CN1CCNCC1CCCCCCCCc1cccc2c1C(=O)NC2=O,,CCOCC,,,,test
US20070167433A1,COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CC(O)C3c3ccc(OC)cc3)cc21.N=C(OC1C=CCC1)C(Cl)(Cl)Cl>>COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CC(OC4C=CCC4)C3c3ccc(OC)cc3)cc21,,ClCCl,,,,test
US20150353489A1,Fc1ccccc1.O=C1C=CC(=O)O1>>O=C(O)/C=C/C(=O)c1ccc(F)cc1,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US05714479,COC(=O)c1nc(CO)ccc1C(=O)c1ccc2c(c1)OCO2.C[Si](C)(C)CCOCCl>>COC(=O)c1nc(COCOCC[Si](C)(C)C)ccc1C(=O)c1ccc2c(c1)OCO2,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100331293A1,Cc1c(Cl)nc2ccc(F)cc2c1Cl.OB(O)c1cncc(F)c1>>Cc1c(-c2cncc(F)c2)nc2ccc(F)cc2c1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O,O=C([O-])[O-].[Na+].[Na+],test
US04267179,CC(=N)N.COc1ccc(N2CCN(c3ccc(NC(=O)NN)cc3)CC2)cc1>>COc1ccc(N2CCN(c3ccc(-n4c(C)n[nH]c4=O)cc3)CC2)cc1,,CN(C)C=O,,Cl,,test
US20120130090A1,FC(F)(F)Sc1ccccc1C#Cc1ccccc1.O=S(=O)(O)C(F)(F)F>>FC(F)(F)[s+]1c(-c2ccccc2)cc2ccccc21.O=S(=O)([O-])C(F)(F)F,,CC#N,ClCCl,CCOCC,,test
US20110152273A1,COC(=O)c1c(C)nc(Cl)nc1Nc1cccc(C)c1.C[S-]>>COC(=O)c1c(C)nc(SC)nc1Nc1cccc(C)c1,,CN(C)C=O,,Cl,,test
US20080188528A1,COC(=O)[C@H](N)CCCNC(=N)NS(=O)(=O)c1c(C)c(C)c2c(c1C)CCC(C)(C)O2.O=C(O)c1cccn(Cc2ccccc2)c1=O>>COC(=O)[C@@H](CCCNC(=N)NS(=O)(=O)c1c(C)c(C)c2c(c1C)CCC(C)(C)O2)NC(=O)c1cccn(Cc2ccccc2)c1=O,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160016935A1,C[C@@H]1CC[C@@H](O)CN1.O=C(O)c1ccsc1-n1nccn1>>C[C@@H]1CC[C@@H](O)CN1C(=O)c1ccsc1-n1nccn1,,ClCCl,O=S(Cl)Cl,CCN(C(C)C)C(C)C,,test
US20090156642A1,CCOC(=O)c1cc(Br)n(-c2ccccc2F)n1.Sc1ccccc1>>CCOC(=O)c1cc(Sc2ccccc2)n(-c2ccccc2F)n1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05216173,COC(=O)c1ccc(Oc2ccc(C(=O)OC)c(C(=O)OC)c2)cc1C(=O)OC>>COC(=O)C1CCC(OC2CCC(C(=O)OC)C(C(=O)OC)C2)CC1C(=O)OC,[Rh],C1CCOC1,,,,test
US05077409,CCCCCCCCCCCCCCOc1cccc(CC(=O)O)c1.O=C(Cl)C(=O)Cl>>CCCCCCCCCCCCCCOc1cccc(CC(=O)Cl)c1,CN(C)C=O,ClCCl,,,,test
US20060177943A1,BrCCOCCOCCOCCOCCOCc1ccccc1.Oc1ccc(OCCOCCOCCOCCOCCOC(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>c1ccc(COCCOCCOCCOCCOCCOc2ccc(OCCOCCOCCOCCOCCOC(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20100099680A1,O=[N+]([O-])c1cccc(S(=O)(=O)CCO)c1>>Nc1cccc(S(=O)(=O)CCO)c1,[Pd],C1CCOC1,CCO,[H][H],,test
US20050009799A1,CCOC(=O)C1CC=C(c2ccc(O)cc2)C(Cc2ccc(OCCN3CCCCC3)cc2)C1C>>CC1C(CO)=CCC(c2ccc(O)cc2)C1Cc1ccc(OCCN2CCCCC2)cc1,,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US20130059835A1,CCOc1c(C(C)Cl)cc(Cl)c(C)c1-c1ccc(C(=O)N(C)C)nc1.Nc1ncnc2[nH]nc(I)c12>>CCOc1c(C(C)n2nc(I)c3c(N)ncnc32)cc(Cl)c(C)c1-c1ccc(C(=O)N(C)C)nc1,,CN(C)C=O,O,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US04061761,CN=C1SCC(O)(c2ccc(Cl)c(S(=O)(=O)Cl)c2)N1C.COc1ccc(CN)c(OC)c1>>CN=C1SCC(O)(c2ccc(Cl)c(S(=O)(=O)NCc3ccc(OC)cc3OC)c2)N1C.Cl,,O,,Br,CCN(CC)CC,test
US20130150343A1,BrCCCOC1CCCCO1.Ic1cn[nH]c1>>Ic1cnn(CCCOC2CCCCO2)c1,,CC#N,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US06124283,CN1CCN(c2cccc3c2C[C@H](N)CC3)CC1.O=C(Cl)c1ccc(Br)cc1>>CN1CCN(c2cccc3c2C[C@H](NC(=O)c2ccc(Br)cc2)CC3)CC1,,ClCCl,,CCN(CC)CC,,test
US05750213,C1CCOC1.C=CC(=O)O.CCOC(=O)N=NC(=O)[O-].O=C(OCCCCCCCCCCCCCCCCOc1ccc(-c2cccc(F)c2F)cc1)C(CCCCCCO)CCCCCCO>>C=CC(=O)OCCCCCCC(CCCCCCOC(=O)C=C)C(=O)OCCCCCCCCCCCCCCCCOc1ccc(-c2cccc(F)c2F)cc1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20020147205A1,N=CN.O=c1[nH]c2cc(F)c(I)cc2c(=O)o1>>Oc1ncnc2cc(F)c(I)cc12,,CN(C)C=O,,CC(=O)O,,test
US20120270865A2,CCOC(=O)CCN(C)C(=O)c1ccc(NC(CC(C)C)c2oc3ccc(OCc4ccccc4)cc3c2C)cc1>>Cc1c(C(CC(C)C)Nc2ccc(C(=O)N(C)CCC(=O)O)cc2)oc2ccc(OCc3ccccc3)cc12,,CCO,,[Na+].[OH-],,test
US20160016936A1,Cc1cc(-c2cn(CCN3CCC3)c(C3CCNCC3(F)F)n2)ccc1F.N#Cc1c(N)ncnc1Cl>>Cc1cc(-c2cn(CCN3CCC3)c(C3CCN(c4ncnc(N)c4C#N)CC3(F)F)n2)ccc1F,,CC#N,,CCN(C(C)C)C(C)C,,test
US20030225097A1,CC(C)(C)C(=O)Cl.N#Cc1c(N)ccc2sc3ccccc3c12>>CC(C)(C)C(=O)Nc1ccc2sc3ccccc3c2c1C#N,,ClCCl,,CCN(CC)CC,,test
US20070254865A1,O=C(O)[C@@H]1CC2(CC[C@H]1c1cc(F)c(F)cc1F)OCCO2.OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>O=C(NC1CC2(CCC1c1cc(F)c(F)cc1F)OCCO2)OCc1ccccc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20030073846A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1cc(C[C@@H](CO)NCc2ccccc2)ccc1OCc1ccccc1>>CC(C)(C)OC(=O)N(Cc1ccccc1)[C@H](CO)Cc1ccc(OCc2ccccc2)c(N)c1,,C1COCCO1,CCOC(C)=O,CCN(CC)CC,,test
US20160200719A1,Clc1ccc(C(c2ccc(Cl)cc2)c2ccc3nncc(NC4CCNCC4)c3c2)cc1.O=CCc1ccccc1>>Clc1ccc(C(c2ccc(Cl)cc2)c2ccc3nncc(NC4CCN(CCc5ccccc5)CC4)c3c2)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US04766127,COC(=O)c1ccc2cc(Cc3cccnc3)ccc2c1.Cl>>Cl.O=C(O)c1ccc2cc(Cc3cccnc3)ccc2c1,,Cl,,,,test
US20120258950A1,CCOC(=O)CC(=O)CCl.NC(=O)C1CC1>>CCOC(=O)Cc1coc(C2CC2)n1,,C1COCCO1,Cc1ccccc1,,,test
US04327102,Cl.Clc1ccc(SCc2ccccn2)cc1Cl.O=C(OO)c1cccc(Cl)c1>>Cl.O=S(Cc1ccccn1)c1ccc(Cl)c(Cl)c1,,ClCCl,,,,test
US04378369,O=C(Cl)c1ccccc1.OC[C@H]1O[C@H](CO)[C@@H](O)[C@@H]1O>>O=C(OC[C@H]1O[C@H](CO)[C@@H](O)[C@@H]1O)c1ccccc1,,C1CCOC1,,CCN(CC)CC,,test
US20130225548A1,O=[N+]([O-])c1ccc(Br)cc1N[C@@H]1CC[C@@H](O)CC1>>Nc1ccc(Br)cc1N[C@@H]1CC[C@@H](O)CC1,,CCO,,[H][H],,test
US20040204402A1,C1=C(c2c[nH]c3ccccc23)CCNC1.Cc1ccc(S(=O)(=O)OCCn2nc3ccccn3c2=O)cc1>>O=c1n(CCN2CC=C(c3c[nH]c4ccccc34)CC2)nc2ccccn12,,CS(C)=O,,CCN(CC)CC,O,test
US04410534,COC(=O)c1ccn2c1C(C(=O)OC)CCC2>>O=C(O)c1ccn2c1C(C(=O)O)CCC2,,O,,CO,[K+].[OH-],test
US20110263564A1,O=C1CCOc2ccc(-c3cccc(C(F)(F)F)c3)nc21>>OC1CCOc2ccc(-c3cccc(C(F)(F)F)c3)nc21,,CO,,[BH4-].[Na+],,test
US20040058964A1,Cc1ccc(CO)cc1-n1c(C)cc(OCc2ccc(F)cc2F)c(Br)c1=O>>Cc1ccc(C=O)cc1-n1c(C)cc(OCc2ccc(F)cc2F)c(Br)c1=O,,CC#N,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20070010528A1,CC(C)(C)OC(=O)N1CCNCC1.CN=c1scc(CCl)n1C>>C/N=c1\scc(CN2CCN(C(=O)OC(C)(C)C)CC2)n1C,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US20140018533A1,CCOC(=O)C1=C(Nc2ccc(Cl)cc2)OCC1=O.O=Cc1c[nH]c2ncccc12>>CCOC(=O)C1=C(Nc2ccc(Cl)cc2)OC(=Cc2c[nH]c3ncccc23)C1=O,,CCO,,C1CCNCC1,,test
US20050101063A1,C#Cc1cccc(Nc2ccccc2C#C[Si](C)(C)C)c1>>C#Cc1ccc(-c2ccccc2C#C)cc1N,,ClCCl,,CO,,test
US20100286112A1,COc1ccc(CC(NC(C)=O)C(=O)O)c(F)c1>>COc1ccc(CC(N)C(=O)O)c(F)c1,,Cl,,,,test
US20150209379A1,OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O.c1ccc2c(c1)CCNC2>>OC[C@H]1O[C@@H](n2cnc3c(N4CCc5ccccc5C4)ncnc32)[C@H](O)[C@@H]1O,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04406689,CCOC(=O)C1CCCCN1.O=C(Cl)Cl>>CCOC(=O)C1CCCCN1C(=O)Cl,,c1ccccc1,,CCN(CC)CC,,test
US20120040962A1,Brc1ccc2c(c1)C=Cc1ccc(Br)cc1O2>>Brc1ccc2c(c1)CCc1ccc(Br)cc1O2,[Pt],CCOC(C)=O,,,,test
US05120841,CC(=O)CC(=O)OCC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)Cc3csc(N)n3)[C@H]2SC1.CC(I)OC(=O)OC1CCCCC1>>CC(=O)CC(=O)OCC1=C(C(=O)OC(C)OC(=O)OC2CCCCC2)N2C(=O)[C@@H](NC(=O)Cc3csc(N)n3)[C@H]2SC1,,CN(C)C=O,,CCOC(C)=O,,test
US20070191336A1,CC(C)C(=O)CC#N.NNc1ccc(C(O)C(F)(F)F)cc1>>CC(C)c1cc(N)n(-c2ccc(C(O)C(F)(F)F)cc2)n1,,CCO,,Cl,Cl,test
US20070135442A1,COc1cc2c(c(N3CCN(CC(F)(F)F)CC3)c1)OC(C(=O)O)CC2.Nc1ccc(N2CCOCC2)cc1>>COc1cc2c(c(N3CCN(CC(F)(F)F)CC3)c1)OC(C(=O)Nc1ccc(N3CCOCC3)cc1)CC2,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100261755A1,COC(=O)N1CC[C@H](c2cc(=O)[nH]o2)C[C@H]1CCC(C)(C)C>>CC(C)(C)CC[C@@H]1C[C@@H](c2cc(=O)[nH]o2)CCN1,,Br,,,,test
US05550129,CCOc1cc2c(C)c(CCOS(C)(=O)=O)c(=O)oc2cc1OC.c1ccc(C2CCNCC2)cc1>>CCOc1cc2c(C)c(CCN3CCC(c4ccccc4)CC3)c(=O)oc2cc1OC,,CCO,,,,test
US20050182072A1,CC(C)(C)OC(=O)N1CC2CC1CN2.Clc1cc(-c2cc3nccn3c(Cl)n2)ccn1>>CC(C)(C)OC(=O)N1CC2CC1CN2c1nc(-c2ccnc(Cl)c2)cc2nccn12,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20070078120A1,COc1cccc(C2(C#N)CCNCC2)c1.O=C1CCCCC1>>COc1cccc(C2(C#N)CCN(C3CCCCC3)CC2)c1,,CC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20010047020A1,CCCOc1nc2cccc(C(=O)OCC)c2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1>>CCCOc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,CCO,,[Na+].[OH-],,test
US20030096826A1,CC(C)(C)OC(=O)C[C@H](N)C(N)=O.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)c(OCc2ccccc2)c1>>CC(C)(C)OC(=O)C[C@H](NS(=O)(=O)c1ccc([N+](=O)[O-])cc1OCc1ccccc1)C(N)=O,,CCOC(C)=O,,ClCCl,c1ccncc1,test
US06492360B1,COc1ccc2c(c1)CNN=C2Cc1c(Cl)cncc1Cl.O=C(Cl)CCl>>COc1ccc2c(c1)CN(C(=O)CCl)N=C2Cc1c(Cl)cncc1Cl,,C1CCOC1,,CCN(CC)CC,,test
US20080045493A1,CC(c1ccc(S(=O)(=O)Cl)cc1)C(F)(F)F.CCCN1CC(c2ccc(N)cc2)C1>>CCCN1CC(c2ccc(NS(=O)(=O)c3ccc(C(C)C(F)(F)F)cc3)cc2)C1,,ClCCl,c1ccncc1,,,test
US20150158815A1,NC(=O)C(Nc1cncc(Br)c1)c1ccccc1.OB(O)c1cncc(Cl)c1>>NC(=O)C(Nc1cncc(-c2cncc(Cl)c2)c1)c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20150239838A1,C=C(N=[N+]=[N-])c1cccc(Cl)c1.CC#N.COC(=O)Cn1nc(C(C)=O)c2ccncc21>>COC(=O)Cn1nc(C(C)=O)c2ccn3cc(-c4cccc(Cl)c4)cc3c21,[Cu]I,,,,,test
US20160038504A1,COC(=O)c1ccc(C)c(B2OC(C)(C)C(C)(C)O2)c1.COc1nnc(Cl)cc1N1CCOCC1>>COC(=O)c1ccc(C)c(-c2cc(N3CCOCC3)c(OC)nn2)c1,,C1CCOC1,,CC(C)c1cc(C(C)C)c(-c2ccccc2P(C2CCCCC2)C2CCCCC2)c(C(C)C)c1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20080161278A1,CC(C)(C)c1cc(N)[nH]n1.Cc1cc(Cl)nc(Cl)n1>>Cc1cc(Nc2cc(C(C)(C)C)[nH]n2)nc(Cl)n1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20130217671A1,CC(=O)c1cnc2ccc(Br)cc2c1N[C@@H]1CC[C@@H](CCN(C)C)CC1.CC1(C)OB(c2cc(Cl)c(O)c(Cl)c2)OC1(C)C.Cl>>CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1N[C@@H]1CC[C@@H](CCN(C)C)CC1.Cl,,CO,,,,test
US20110071126A1,O=C(O)CCc1ccc(Br)cc1>>O=C1CCc2ccc(Br)cc21,,ClCCl,O=S(Cl)Cl,[Al+3].[Cl-].[Cl-].[Cl-],,test
US04767780,CCC(=O)N1CCC(=O)c2cc(Cl)ccc21.COC(OC)N(C)C>>CCC(=O)N1CC(=CNC)C(=O)c2cc(Cl)ccc21,,c1ccccc1,,CCN(CC)CC,,test
US20150344489A1,CCOc1ncccc1[C@]1(NC(=O)N2CC3(C2)CN(C(=O)OC(C)(C)C)C3)C(=O)N(S(=O)(=O)c2ccc(OC)cc2)c2ccc(C#N)cc21>>CCOc1ncccc1[C@]1(NC(=O)N2CC3(CNC3)C2)C(=O)N(S(=O)(=O)c2ccc(OC)cc2)c2ccc(C#N)cc21,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20090131433A1,CC(C)(C)OC(=O)NC[C@@H]1C[C@@H](Oc2ccc(CN3CCCC3)cc2)C1>>NC[C@@H]1C[C@@H](Oc2ccc(CN3CCCC3)cc2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130116263A1,CCn1c(=O)c(-c2ccc(-c3nccnc3C)cc2Cl)cc2cnc(NC3CCN(C(=O)OC(C)(C)C)C3)nc21>>CCn1c(=O)c(-c2ccc(-c3nccnc3C)cc2Cl)cc2c(C(C)(C)C)nc(NC3CCNC3)nc21,,CO,,Cl,,test
US05545748,CCCCCCCC(=O)OCC(=O)OCC(=O)O.O=C(Cl)C(=O)Cl>>CCCCCCCC(=O)OCC(=O)OCC(=O)Cl,,CCCCCC,,,,test
US20110166123A1,CCOC(=O)c1cn([C@@H](C(C)(C)C)C(C)(C)O[SiH2]C(C)(C)C)c2nc(C)c(Cc3cccc(Cl)c3F)cc2c1=O>>Cc1nc2c(cc1Cc1cccc(Cl)c1F)c(=O)c(C(=O)O)cn2[C@H](CO)C(C)(C)C,,CO,,O,C[O-].[Na+],test
US20040192686A1,CCOC(=O)CN.[O-][n+]1nc(Cl)nc2ccccc21>>CCOC(=O)CNc1nc2ccccc2[n+]([O-])n1,,COCCOC,,CCN(CC)CC,Cl,test
US20050234244A1,COc1c(F)cc(N)cc1F.O=N[O-]>>COc1c(F)cc(NN)cc1F,,Cl,O,Cl[Sn]Cl,,test
US20020032208A1,COC(=O)Oc1cc(N)c(F)cc1C.COc1cc2c(Cl)ncnc2cc1OCc1ccccc1.Cl>>COC(=O)Oc1cc(Nc2ncnc3cc(OCc4ccccc4)c(OC)cc23)c(F)cc1C.Cl,,CC(C)O,,,,test
US20030166684A1,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.O=C(Cl)C(=O)Cl.O=C(O)CO>>CC(C)(C)[Si](C)(C)OCC(=O)Cl,CN(C)C=O,ClCCl,c1ccncc1,,,test
US20060241106A1,C1COCCN1.CCNC(=O)c1noc(-c2cc(CC(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)c1-c1ccc(C=O)cc1>>CCNC(=O)c1noc(-c2cc(CC(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)c1-c1ccc(CN2CCOCC2)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20020111340A1,C[C@@H]1CC[C@@H](C)N1.O=C(c1ccc(-c2ccc(OCCCCl)cc2)cc1)N1CCOCC1>>C[C@@H]1CC[C@@H](C)N1CCCOc1ccc(-c2ccc(C(=O)N3CCOCC3)cc2)cc1,,CCC(C)=O,,Cl,[I-].[K+],test
US20100298324A1,COc1cnc(-n2c(=S)[nH]c3cc(C(=O)O)c(Cl)cc3c2=O)nc1OC.NCc1ccc(Cl)cc1>>COc1cnc(-n2c(=S)[nH]c3cc(C(=O)NCc4ccc(Cl)cc4)c(Cl)cc3c2=O)nc1OC,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120220575A1,BrCc1ccccc1.O=C1Nc2cnc(Cl)nc2N2CCOCC12>>O=C1C2COCCN2c2nc(Cl)ncc2N1Cc1ccccc1,,CN(C)C=O,,[Li],,test
US20160009726A1,CC1CC1c1cc2ccc(C(=O)O)nc2o1.C[C@H]1CN(c2ccncc2N)C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C>>CC1CC1c1cc2ccc(C(=O)Nc3cnccc3N3C[C@@H](NC(=O)OC(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)C3)nc2o1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130029980A1,CCOC(=O)CCc1ccc(CN2CC(C)OC(C)C2)cc1>>CC1CN(Cc2ccc(CCCO)cc2)CC(C)O1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140349990A1,CC(=O)O/N=C(\C)c1cccc(C)c1O>>Cc1noc2c(C)cccc12,,c1ccncc1,,,,test
US20100075965A1,Cc1ccc(S(=O)(=O)Cl)cc1.Cc1nc(N)ccc1Br>>Cc1ccc(S(=O)(=O)Nc2ccc(Br)c(C)n2)cc1,,c1ccncc1,,O,,test
US20140336185A1,COC(=O)CN.N#Cc1ccc(CBr)cc1>>COC(=O)CNCc1ccc(C#N)cc1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US04889858,CCOC(=O)c1cc(F)ccc1CBr.Oc1cccc(F)c1>>CCOC(=O)c1cc(F)ccc1COc1cccc(F)c1,,CCO,,O,[Na],test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OC(C)C(C)(C)O)CC2)c2nc(C)nn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n([C@@H]2CC[C@@H](OC(C)C(C)(C)O)CC2)c2nc(C)nn12,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US20090197871A1,C1CNCCN1.CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(C)c(-c3cccc(C=O)c3)c2)c1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(C)c(-c3cccc(CN4CCNCC4)c3)c2)c1,,CCOC(C)=O,ClCCl,O=C(O)C(F)(F)F,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05189054,CCOC(=O)c1[nH]c2cc(Cl)c(C(=O)OC(C)(C)C)c(Cl)c2c1NCS(=O)(=O)c1ccccc1>>CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1NCS(=O)(=O)c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04855292,Cc1c(N2CCC(CNC(=O)OC(C)(C)C)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12.Cl>>Cc1c(N2CCC(CN)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12.Cl,,CCO,,,,test
US20070072853A1,COC(C)(C)c1nc2cc(N(C)S(=O)(=O)c3ccc([N+](=O)[O-])cc3)ccc2n1CC1CCOCC1>>COC(C)(C)c1nc2cc(N(C)S(=O)(=O)c3ccc(N)cc3)ccc2n1CC1CCOCC1,[Pd],CCOC(C)=O,,,,test
US20130116236A1,COc1ccc(Cn2nnc3c(N4CCOCC4)nc(C(C)(C)C)nc32)cc1>>CC(C)(C)c1nc(N2CCOCC2)c2nn[nH]c2n1,,O=C(O)C(F)(F)F,,,,test
US20150065468A1,COc1cc2nc(-c3ccc(CC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c(F)c3)cnc2cc1OC1CN(C(=O)OC(C)(C)C)C1>>COc1cc2nc(-c3ccc(CC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c(F)c3)cnc2cc1OC1CNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030225097A1,CCOC(=O)C=C(C)c1ccncc1>>CCOC(=O)CC(C)c1ccncc1,[Pd],CCO,,,,test
US20090137572A1,COc1cc(NC(=N)N)cc(OC)c1.Cc1nc(N=CN(C)C)sc1C(=O)C=CN(C)C>>COc1cc(Nc2nccc(-c3sc(N)nc3C)n2)cc(OC)c1,,CC#N,,,,test
US20150087639A1,CCCOCCN(CCOCCC)c1ccc(N)cc1F.COC(=O)/C=C(/C)NC(C)=O>>CCCOCCN(CCOCCC)c1ccc(-n2c(C)nc(C)cc2=O)cc1F,,ClCCl,,C[Al](C)C,,test
US20060138453A1,Cc1ccccc1.[Li]c1ccccc1.c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)ccnc23)cc1>>c1ccc(-c2cc(-c3ccccc3)c3ccc4c(-c5ccccc5)cc(-c5ccccc5)nc4c3n2)cc1,,C1CCOC1,Cc1ccccc1,O,,test
US20100317645A1,CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3ccc(C(N)=NO)cc32)cc1.CCOC(=O)Cl>>CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3ccc(-c4noc(=O)[nH]4)cc32)cc1,,CN(C)C=O,ClCCl,c1ccncc1,,test
US20150252038A1,CO.O=C(O)C1CCN(Cc2cc(Cl)cc(Cl)c2)C(=O)C1>>COC(=O)C1CCN(Cc2cc(Cl)cc(Cl)c2)C(=O)C1,,O=S(Cl)Cl,,,,test
US07115624B1,CC(C)(C)OC(=O)c1c(NC(=O)OCc2ccccc2)sc2c1CC(CN1Cc3ccccc3C1=O)N(C(=O)OC(C)(C)C)C2>>CC(C)(C)OC(=O)c1c(N)sc2c1CC(CN1Cc3ccccc3C1=O)N(C(=O)OC(C)(C)C)C2,[Pd],CO,,,,test
US04081477,CC1C(C(=O)Cl)CC2CC1C2(C)C.CO>>COC(=O)C1CC2CC(C1C)C2(C)C,,c1ccncc1,,,,test
US20160009683A1,COCCBr.Oc1ccc(I)cc1>>COCCOc1ccc(I)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060235033A1,COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1N.Cc1csc(C(C)N)n1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)NC(C)c4nc(C)cs4)cc3)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20110275703A1,CCc1ccc(Cc2cc3c(cc2C#C[Si](C)(C)C)CO[C@]32O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)cc1>>C#Cc1cc2c(cc1Cc1ccc(CC)cc1)[C@]1(OC2)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20070249670A1,COC(=O)[C@@H](NC(=O)c1cc(-c2cnn(C)c2)sc1NC(=O)Nc1c(Cl)cccc1Cl)C1CCCCC1>>Cn1cc(-c2cc(C(=O)N[C@H](C(=O)O)C3CCCCC3)c(NC(=O)Nc3c(Cl)cccc3Cl)s2)cn1,,C1CCOC1,,[Li+].[OH-],,test
US20150203534A1,CC(C)(C)OC(=O)N[C@@H](COC(F)F)C(=O)N[C@@H](COC(F)F)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1.O=C(O)C(F)(F)F>>C[C@]1(C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](COC(F)F)NC(=O)[C@@H](N)COC(F)F)CO1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20120095064A1,CC(=O)Nc1ccn(Cc2c(F)cccc2Cl)n1>>Nc1ccn(Cc2c(F)cccc2Cl)n1,,CCO,,[Na+].[OH-],,test
US20130281433A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(-c4ccc5c(c4)n(C)c(=O)n5C)c3)sc2c1OS(=O)(=O)C(F)(F)F.OB(O)c1ccc(Cl)cc1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(-c4ccc5c(c4)n(C)c(=O)n5C)c3)sc2c1-c1ccc(Cl)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20120142665A1,CCOC(=O)c1c(C(=O)N2CCC2)cnn1C.Cc1c(N)ccn2nc(-c3ccccc3)nc12>>Cc1c(NC(=O)c2c(C(=O)N3CCC3)cnn2C)ccn2nc(-c3ccccc3)nc12,,C1COCCO1,,C[Al](C)C,,test
US20160194296A1,Cc1ccccc1N1CCNCC1.O=C1c2ccccc2C(=O)N1CCCBr>>Cc1ccccc1N1CCN(CCCN2C(=O)c3ccccc3C2=O)CC1,,CC#N,,CCN(CC)CC,,test
US20070155839A1,COc1ccc(C(=O)c2ccc(Br)cc2F)cc1>>O=C(c1ccc(O)cc1)c1ccc(Br)cc1F,,c1ccccc1,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US04328234,CC1(C)C2CCC(CCn3ccnc3)C1C2.O=C(O)C(=O)O>>CC1(C)C2CCC(CCn3ccnc3)C1C2.O=C(O)C(=O)O,,CCO,,,,test
US20140213586A1,COC(=O)CCc1ccc2[nH]ccc2c1>>OCCCc1ccc2[nH]ccc2c1,,C1CCOC1,CCO,[BH4-].[Li+],,test
US20120015957A1,CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(Br)cc2F)CC1.OB(O)c1ccccc1>>CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(-c3ccccc3)cc2F)CC1,,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US05198552,CCOC(=O)c1c(CSc2ccccc2)n(C)c2cc(Br)c(O)cc12.CN(C)CN(C)C>>CCOC(=O)c1c(CSc2ccccc2)n(C)c2cc(Br)c(O)c(CN(C)C)c12,,O,,,,test
US20090186870A1,CO.Cc1cc(Cl)c(C(=O)O)cc1[N+](=O)[O-]>>COC(=O)c1cc([N+](=O)[O-])c(C)cc1Cl,,CO,,CC(=O)Cl,,test
US20150210682A1,COCCCOc1cc(CC(CC(F)(F)F)NC=O)ccc1OC>>COCCCOc1cc2c(cc1OC)C=NC(CC(F)(F)F)C2,,CC#N,,O=P(Cl)(Cl)Cl,,test
US20160194292A1,CCOc1ccc(B2OC(C)(C)C(C)(C)O2)cc1CC(=O)OC.O=c1n(-c2ccc(C(F)(F)F)cc2)nc(CCCc2ccc(Br)cc2)n1-c1ccccc1F>>CCOc1ccc(-c2ccc(CCCc3nn(-c4ccc(C(F)(F)F)cc4)c(=O)n3-c3ccccc3F)cc2)cc1CC(=O)OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])O.[Na+],,test
US20120157494A1,NCC1CCOCC1.O=C1OC(=O)c2c(F)cccc21>>O=C1c2cccc(F)c2C(=O)N1CC1CCOCC1,,CC(=O)O,,,,test
US20150031861A1,C#CCN(NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C.[N-]=[N+]=Nc1ccc(CBr)cc1>>C#CCN(C(=O)OC(C)(C)C)N(Cc1ccc(N=[N+]=[N-])cc1)C(=O)OC(C)(C)C,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US06498172B1,COC(=O)CCc1cccc(CNCc2ccc3c(c2)OCO3)c1.O=S(=O)(Cl)c1ccccc1>>COC(=O)CCc1cccc(CN(Cc2ccc3c(c2)OCO3)S(=O)(=O)c2ccccc2)c1,,CCN(CC)CC,,,,test
US20120232051A1,CNc1cnccc1-c1ccccc1C.O=C(Cl)c1cccc(C(F)(F)F)c1>>Cc1ccccc1-c1ccncc1N(C)C(=O)c1cccc(C(F)(F)F)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150291604A1,CC1(N)CCN(C(=O)OC(C)(C)C)C1.OCCc1c(Cl)nc(N2CCOCC2)nc1Cl>>CC1(Nc2nc(N3CCOCC3)nc(Cl)c2CCO)CCN(C(=O)OC(C)(C)C)C1,,CCOC(C)=O,CN1CCCC1=O,CCN(C(C)C)C(C)C,,test
US20070066624A1,CC(C)(C)OC(=O)N1CCC(N2C(=O)NC[C@H]2c2ccccc2)CC1.CONC(=O)Oc1ccc([N+](=O)[O-])cc1>>CONC(=O)N1C[C@@H](c2ccccc2)N(C2CCN(C(=O)OC(C)(C)C)CC2)C1=O,,C1CCOC1,,[H-].[Na+],,test
US20100249123A1,COc1ccc(C(=O)Nc2ccc(C(C)(C)CCN)cc2)cc1OC.O=C(O)c1cnc2ccccn12>>COc1ccc(C(=O)Nc2ccc(C(C)(C)CCNC(=O)c3cnc4ccccn34)cc2)cc1OC,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20090111790A1,C[C@@H](COC(F)F)Oc1cc(O)cc(C(=O)Nc2ccn(C)n2)c1.O=C(c1cnc(Cl)c(Cl)c1)N1CCC1>>C[C@@H](COC(F)F)Oc1cc(Oc2ncc(C(=O)N3CCC3)cc2Cl)cc(C(=O)Nc2ccn(C)n2)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140179680A1,CCOC(=O)CN[C@H]1CCC[C@@H]1NC(=O)OC(C)(C)C>>CCOC(=O)CN[C@H]1CCC[C@@H]1N,,C1COCCO1,,Cl,,test
US20040077675A1,COc1cc(NC(=O)Cc2cccc(N)c2)cc(OC)c1OC.O=C(O)c1c(-c2c(F)cccc2Cl)noc1-c1ccccc1>>COc1cc(NC(=O)Cc2cccc(NC(=O)c3c(-c4c(F)cccc4Cl)noc3-c3ccccc3)c2)cc(OC)c1OC,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US05747422,COc1cc(-c2ncc(C(F)(F)F)cc2Cl)ccc1C#N>>N#Cc1ccc(-c2ncc(C(F)(F)F)cc2Cl)cc1O,,O,,Cl,c1ccncc1,test
US20150376219A1,CCI.O=c1c(-c2ccccc2)cn(-c2ncnc3nc[nH]c23)cc1-c1ccccc1>>CCn1cnc2c(-n3cc(-c4ccccc4)c(=O)c(-c4ccccc4)c3)ncnc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04499295,CCCCCCCCCCCCCCCCCC(O)c1ccc(O)c(C(=O)O)c1>>CCCCCCCCCCCCCCCCC=Cc1ccc(O)c(C(=O)O)c1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05021430,COC(=O)[C@H](CSCc1ccccc1)NC(=O)[C@H](Cc1ccccc1)C[C@@H](Cc1ccccc1)C(=O)O.Nc1ccccn1>>COC(=O)[C@H](CSCc1ccccc1)NC(=O)[C@H](Cc1ccccc1)C[C@@H](Cc1ccccc1)C(=O)Nc1ccccn1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20120142691A1,Nc1nnc[nH]1.O=C(O)c1ncccc1OC[C@H]1CCCN1C(=O)[C@@H]1CC[C@@H](C(F)(F)F)CC1>>O=C(Nc1nnc[nH]1)c1ncccc1OC[C@H]1CCCN1C(=O)[C@@H]1CC[C@@H](C(F)(F)F)CC1,,CN(C)C=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20060199817A1,C=CCOC(=O)N1C(C)CC[C@@H]1C(=O)NC(C)C>>CC(C)NC(=O)[C@H]1CCC(C)N1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,,[BH4-].[Na+],,test
US20110098288A1,CC(C)(C)OC(=O)N1CCC(COc2cccc(Nc3ncc(Cl)c(Nc4ccccc4NS(C)(=O)=O)n3)c2)CC1>>CS(=O)(=O)Nc1ccccc1Nc1nc(Nc2cccc(OCC3CCNCC3)c2)ncc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070208059A1,CCOC(=O)c1nc(-c2ccc(Cl)cc2Cl)n(-c2ccc(OCc3ccccc3)cc2)c1C>>Cc1c(C(=O)O)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OCc2ccccc2)cc1,,CO,O,Cl,[K+].[OH-],test
US20090197863A1,CCC=O.NC(=O)c1cccc2nc(-c3ccc(C4CCNCC4)cc3F)oc12>>CCCN1CCC(c2ccc(-c3nc4cccc(C(N)=O)c4o3)c(F)c2)CC1,[Pd],CO,,[H][H],,test
US20130184284A1,N#Cc1ccc(N2CCCC(O)C2)c(F)c1>>N#Cc1ccc(N2CCCC(=O)C2)c(F)c1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20050176724A1,CC(C)(C)OC(=O)N1CCC(=Cc2cccc(-c3ccncc3)c2)CC1>>CC(C)(C)OC(=O)N1CCC(Cc2cccc(-c3ccncc3)c2)CC1,O=[Pt],CCO,,,,test
US20140228409A1,CC(CC(=O)O)CC(=O)Nc1ccc(C#N)cc1.CO>>COC(=O)CC(C)CC(=O)Nc1ccc(C#N)cc1,O=S(=O)(O)O,CO,,CCOC(C)=O,,test
US20110118245A1,CC(C)c1cc(NC(=O)Oc2ccccc2)on1.COc1cc2ncnc(Oc3cccc(N)c3)c2cc1OC>>COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)C)no4)c3)c2cc1OC,CN(C)c1ccncc1,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US06133279,CC(=O)Oc1c(C(C)(C)C)cc2c(c1C(C)(C)C)CC(C)(COS(C)(=O)=O)O2.[I-]>>CC(=O)Oc1c(C(C)(C)C)cc2c(c1C(C)(C)C)CC(C)(CI)O2,,CN(C)C=O,,O,,test
US20040248887A1,C[C@@H](CNc1ccc(OC(F)(F)F)cc1)NC(=O)[C@H](CC1CCCCC1)NC(=O)OCc1ccccc1>>C[C@@H](CNc1ccc(OC(F)(F)F)cc1)NC(=O)[C@@H](N)CC1CCCCC1,[Pd],CO,,,,test
US05157047,CCOCCl.FC(F)(F)c1[nH]c(-c2ccc(Cl)c(Cl)c2)c(Br)c1C(F)(F)F>>CCOCn1c(-c2ccc(Cl)c(Cl)c2)c(Br)c(C(F)(F)F)c1C(F)(F)F,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US05688946,CC(C)(C)OC(=O)[C@@H]1CCCN1.CCOC(=O)C(Cc1ccccc1)CS(=O)(=O)Cl>>CCOC(=O)C(Cc1ccccc1)CS(=O)(=O)N1CCC[C@H]1C(=O)OC(C)(C)C,,CCN(CC)CC,,,,test
US05610174,COc1ccc2c(c1[N+](=O)[O-])CCCC2(C#N)O[Si](C)(C)C>>COc1ccc2c(c1[N+](=O)[O-])CCC=C2C#N,,CC(=O)O,,CC(=O)Cl,,test
US20050054626A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](NC(=O)OCc2ccccc2)[C@H](CS(C)(=O)=O)C1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@H](N)[C@H](CS(C)(=O)=O)C1,[Pd],CO,,[H][H],,test
US05342835,C1COCCN1.COc1ccc(-c2cc(-c3ccc(F)cc3)ccc2C(=O)O)cc1OC>>COc1ccc(-c2cc(-c3ccc(F)cc3)ccc2C(=O)N2CCOCC2)cc1OC,,C1CCOC1,,,,test
US20030149019A1,CN1CCNCC1.O=[N+]([O-])c1cc(S(=O)(=O)Nc2cccc(Cl)c2)ccc1Cl>>CN1CCN(c2ccc(S(=O)(=O)Nc3cccc(Cl)c3)cc2[N+](=O)[O-])CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20030220359A1,COC(=O)C(C(=O)OC)c1ccc(Cl)cc1.N=CN>>Oc1ncnc(O)c1-c1ccc(Cl)cc1,,CO,,Cl,C[O-].[Na+],test
US04077982,O=Cc1cccc(F)c1.OCC(O)CO>>OC1COC(c2cccc(F)c2)OC1,,c1ccccc1,,O,O=S(=O)(O)O,test
US20120149694A1,O=C(N1CCOCC1)N1CC(CS(=O)(=O)[O-])CC(c2ccc(C(F)(F)F)cc2)C1.SC1CCCCC1>>O=C(N1CCOCC1)N1CC(CSC2CCCCC2)CC(c2ccc(C(F)(F)F)cc2)C1,,CN(C)C=O,,O,[H-].[Na+],test
US20100240642A1,O=Cc1cc(O)cc(OCc2ccccc2)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=Cc1cc(OCc2ccccc2)cc(OS(=O)(=O)C(F)(F)F)c1,,ClCCl,,,,test
US20100286390A1,NCc1ccncc1.O=C(O)Cn1ncc(Br)c(Br)c1=O>>O=C(Cn1ncc(Br)c(Br)c1=O)NCc1ccncc1,CN(C)C=O,C1CCOC1,O,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20040167155A1,COc1ccc(S(=O)(=O)NC(C)c2cc(F)ccc2-c2ccc(F)cc2F)c(OC)c1>>COc1ccc(S(=O)(=O)N2c3cc(F)ccc3-c3ccc(F)cc3C2C)c(OC)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060211709A1,N#Cc1nc(-c2cccc(CO)c2)cnc1N.NNC(=O)c1cccs1>>Nc1ncc(-c2cccc(CO)c2)nc1-c1nc(-c2cccs2)n[nH]1,,CO,,C[O-].[Na+],,test
US05607929,O=C(OO)c1cccc(Cl)c1.O=C1Nc2ccccc2Sc2ccccc21>>O=C1Nc2ccccc2S(=O)c2ccccc21,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20110212918A1,CC(C)c1cc([N+](=O)[O-])cnc1Cl.SCc1ccccc1>>CC(C)c1cc([N+](=O)[O-])cnc1SCc1ccccc1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20080153836A1,COC(=O)c1cc(-c2ccnn2C(C)C)c(CF)cc1N.CS(=O)(=O)NN.ClCCl.[OH-]>>CC(C)n1nccc1-c1cc2c(=O)n(NS(C)(=O)=O)c(=O)[nH]c2cc1CF,,ClCCl,,CCN(CC)CC,,test
US20090118199A1,CN(C)c1ccc(CCOc2ccc(C3=N/C(=C\c4ccc(OC(F)(F)F)cc4)C(=O)O3)cc2)cc1.NCCO>>CN(C)c1ccc(CCOc2ccc(C(=O)N/C(=C\c3ccc(OC(F)(F)F)cc3)C(=O)NCCO)cc2)cc1,,CO,,CCO,,test
US20110034451A1,CCC(O)CC.Cc1cc2nnc(N)n2nc1Cl>>CCC(CC)Oc1nn2c(N)nnc2cc1C,,CN(C)C=O,,[H-].[Na+],,test
US20110275608A1,COC(=O)c1sc(NC(=O)OC(C)(C)C)c(C#N)c1C>>Cc1c(C(=O)O)sc(NC(=O)OC(C)(C)C)c1C#N,,CO,O,[Na+].[OH-],,test
US20050124656A1,CCCCCCCCCCCCN.O=C(Cl)c1ccc(CCl)cc1>>CCCCCCCCCCCCNC(=O)c1ccc(CCl)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20060229301A1,O=C1c2ccccc2OC2(CCNCC2)CN1Cc1ccccc1.O=CCCc1ccccc1>>O=C1c2ccccc2OC2(CCN(CCCc3ccccc3)CC2)CN1Cc1ccccc1,,C1CCOC1,,,,test
US04018802,CCCCC[C@H](O)C#CCC(CCCCCCC(=O)O)S(C)(=O)=O>>CCCCC[C@H](O)CCCC(CCCCCCC(=O)O)S(C)(=O)=O,[Pt],C1CCCCC1,CCOC(C)=O,[H][H],,test
US05895787,CO.OCc1c[nH]c2ccccc12>>COCc1c[nH]c2ccccc12,,O,,,,test
US04705786,CC(=O)Cc1nc(CCl)no1.COC(=O)/C=C(/C)N.O=Cc1cccc(F)c1>>COC(=O)C1=C(C)NC(C)=C(c2nc(CCl)no2)C1c1cccc(F)c1,,CC(C)O,,,,test
US20100145047A1,CCn1c(C(=O)Nc2ccc(N3CCN(C(=O)[C@@H]4CC[C@@H](C(=O)OCc5ccccc5)CC4)CC3)nc2)cc2c(OC)cccc21>>CCn1c(C(=O)Nc2ccc(N3CCN(C(=O)[C@@H]4CC[C@@H](C(=O)O)CC4)CC3)nc2)cc2c(OC)cccc21,[Pd],CO,,,,test
US20070185168A1,CCOC(=O)N1CCC(O)(c2ccc(Cl)s2)CC1>>OC1(c2ccc(Cl)s2)CCNCC1,,CC(C)O,,[K+].[OH-],,test
US20150133428A1,CC(CO)NC(=O)OC(C)(C)C.CCOC(=O)c1[nH]nc(I)c1C(=O)OCC>>CCOC(=O)c1c(I)nn(CC(C)NC(=O)OC(C)(C)C)c1C(=O)OCC,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090203677A1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)C1(C(=O)OC)CC1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)C1(C(=O)O)CC1,,C1CCOC1,,O,[Li+].[OH-],test
US06936602B1,CCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3c2ccccc2)cc1>>CCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3c2ccccc2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20140128598A1,BrBr.COc1ccc(CCC#N)cc1OC>>COc1cc(Br)c(CCC#N)cc1OC,,CC(=O)O,,O,CC(=O)[O-].[Na+],test
US20040116509A1,CC(=O)O[C@H]1C[C@H](C)CC[C@H]1C(=O)O.O=C(Cl)C(=O)Cl>>CC(=O)O[C@H]1C[C@H](C)CC[C@H]1C(=O)Cl,CN(C)C=O,ClCCl,,,,test
US20130017194A1,CC(C)(C)OC(=O)N1C=C(OS(=O)(=O)C(F)(F)F)CC1.O=[N+]([O-])c1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)N1C=C(c2ccc([N+](=O)[O-])cc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US20020002158A1,CC(CNS(=O)(=O)C(C)C)c1ccc(Br)cc1.CCCC[Sn](CCCC)(CCCC)c1ccco1>>CC(CNS(=O)(=O)C(C)C)c1ccc(-c2ccco2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOCC,,,test
US20110028390A1,COC(=O)c1ccc2nn(C)cc2c1>>Cn1cc2cc(C(=O)O)ccc2n1,,CO,,Cl,[Li+].[OH-],test
US20070021606A1,C1CCNC1.O=C(O)COCc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl>>O=C(COCc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl)N1CCCC1,,ClCCl,,CCN=C=NCCCN(C)C,,test
US20100105642A1,COC(CCl)OC.NC1CCCCC1>>COC(CNC1CCCCC1)OC,,O,,[Na+].[OH-],,test
US20050075357A1,CCOC(=O)C(C(=O)OCC)c1c(F)cc(F)cc1F.NC(N)=O>>Oc1nc(O)c(-c2c(F)cc(F)cc2F)c(O)n1,,CCO,,[H-].[Na+],,test
US20080015200A1,CN1CCN(c2nc(Cl)nc3c2oc2ccc(Cl)cc23)CC1.COc1ccc(CN)cc1>>COc1ccc(CNc2nc(N3CCN(C)CC3)c3oc4ccc(Cl)cc4c3n2)cc1,,c1ccncc1,,,,test
US04981850,CCOC(CC)(OCC)OCC.Cn1c(N)c(C(N)=O)sc1=S>>CCc1nc2c(sc(=S)n2C)c(=O)[nH]1,,CC(=O)OC(C)=O,,,,test
US20150232481A1,C=CC[C@@H](C)O.COC(=O)c1ccc(C)cc1O>>C=CC[C@H](C)Oc1cc(C)ccc1C(=O)OC,,Cc1ccccc1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040077622A1,COC(=O)c1cc2c(o1)CCC2>>OCc1cc2c(o1)CCC2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05266570,CCOCC(=O)NC1CCN(C[C@]23C[C@H](c4ccccc42)c2ccc(Cl)cc23)CC1.Cl>>CCOCC(=O)NC1CCN(C[C@]23C[C@H](c4ccccc42)c2ccc(Cl)cc23)CC1.Cl,,CCOCC,,,,test
US20030087926A1,C1=CCC=C1.CCC(=O)C(=O)[O-].Nc1cc(Cl)cc(Cl)c1>>CCOC(=O)C1Nc2cc(Cl)cc(Cl)c2C2C=CCC12,,CC#N,,O=C(O)C(F)(F)F,,test
US07465808B2,COc1ccc(-n2nc(C[C@@H](c3cccc(C)c3)c3nnnn3CCC#N)cc2-c2ccc(Cl)c(Cl)c2)cc1>>COc1ccc(-n2nc(C[C@@H](c3cccc(C)c3)c3nnn[nH]3)cc2-c2ccc(Cl)c(Cl)c2)cc1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20090111809A1,CC(C)[Si](OC1CCN(N2CC[C@@H](Cc3ccc(O)cc3Cl)C2=O)CC1)(C(C)C)C(C)C.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)[Si](OC1CCN(N2CC[C@@H](Cc3ccc(OS(=O)(=O)C(F)(F)F)cc3Cl)C2=O)CC1)(C(C)C)C(C)C,,ClCCl,,c1ccncc1,,test
US20020019526A1,Clc1ncnc2[nH]ccc12.SC1CCCCC1>>c1nc(SC2CCCCC2)c2cc[nH]c2n1,,C1CCOC1,,Cl,CC(C)(C)[O-].[K+],test
US04314065,CNc1ccc(O)cc1.Clc1nc2ccccc2[nH]1>>CN(c1ccc(O)cc1)c1nc2ccccc2[nH]1,,CC#N,O,,,test
US20110245236A1,Cc1ccc([N+](=O)[O-])c(C(=O)Cl)c1.Nc1cccnc1Cl>>Cc1ccc([N+](=O)[O-])c(C(=O)Nc2cccnc2Cl)c1,,C1CCOC1,O,c1ccncc1,,test
US20080161294A1,COc1cc(-n2cccn2)ccc1C(=O)O.O=S(Cl)Cl>>COc1cc(-n2cccn2)ccc1C(=O)Cl,,ClCCl,,CN1CCCC1=O,,test
US20120238574A1,CC(C)(C)OC(=O)N1CCC(=Cc2ccc([N+](=O)[O-])cc2)CC1>>O=[N+]([O-])c1ccc(C=C2CCNCC2)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US05629428,CCCCCCCCOc1ccc(B(O)O)cc1.Clc1cc(Br)cnc1Br>>CCCCCCCCOc1ccc(-c2ncc(Br)cc2Cl)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20130203745A1,O=C1COC(c2ccc(Br)cc2)CN1Cc1ccccc1>>Brc1ccc(C2CN(Cc3ccccc3)CCO2)cc1,,C1CCOC1,,B,CO,test
US20020183369A1,C[Si](C)(C)C#Cc1cc2cc(C(=O)N[C@@H](Cc3ccccc3)C(=O)N3CC(O)C3)[nH]c2s1>>C#Cc1cc2cc(C(=O)N[C@@H](Cc3ccccc3)C(=O)N3CC(O)C3)[nH]c2s1,,CO,,[K+].[OH-],,test
US20070049618A1,Cc1ncoc1C(=O)Cl.NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O>>Cc1ncoc1C(=O)NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O,,CC#N,,CCN(CC)CC,Cl,test
US20110144105A1,CSc1ccc(C=O)cc1C(F)(F)F.O=S(=O)(c1ccccc1)n1ccc2cccnc21>>CSc1ccc(C(O)c2cc3cccnc3n2S(=O)(=O)c2ccccc2)cc1C(F)(F)F,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US06069156,CCCc1[nH]c2cc(C(=O)O)ccc2c1C(=O)C(C)C.OCc1ccccc1>>CCCc1[nH]c2cc(C(=O)OCc3ccccc3)ccc2c1C(=O)C(C)C,CN(C)c1ccncc1,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20150080392A1,CCN.O=Cc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1>>CCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20040110804A1,CON(Cc1ccc(C(=O)OC(C)(C)C)cc1)C(=O)C1=C(O)C(=O)N(C)C1>>CON(Cc1ccc(C(=O)O)cc1)C(=O)C1=C(O)C(=O)N(C)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110071197A1,COC(=O)c1cc(Oc2ccc([N+](=O)[O-])cc2)ccc1NC(C)=O>>COC(=O)c1cc(Oc2ccc([N+](=O)[O-])cc2)ccc1N,,CO,,Cl,O=C([O-])O.[Na+],test
US20150322073A1,COC[C@H](C)Nc1cc2c(cc1NC(=O)c1cc(C)c(=O)n(C)c1)C(C)(C)C(=O)N2C>>COC[C@H](C)n1c(-c2cc(C)c(=O)n(C)c2)nc2cc3c(cc21)N(C)C(=O)C3(C)C,,CC(=O)O,,,,test
US20060160803A1,COCCN.O=C(O)c1cc([N+](=O)[O-])cc(C(F)(F)F)c1>>COCCNC(=O)c1cc([N+](=O)[O-])cc(C(F)(F)F)c1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20100173955A1,CC(C(=O)OC(C)(C)C)c1ccc(Oc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(C#N)c1>>CC(C(=O)O)c1ccc(Oc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(C#N)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140163031A1,CCO.CCOC(C)=O.COc1ccccc1-n1nc(B2OC(C)(C)C(C)(C)O2)cc1-c1ccc(Cl)cc1>>COc1ccccc1-n1nc(C2=C[C@H](C)O[C@@H](C)C2)cc1-c1ccc(Cl)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US05420276,CC(C)(C)[Si](C)(C)Cl.Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@H]2O[C@H]21>>CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2O[C@@H]21,,c1ccncc1,,O,,test
US20070167443A1,CCOC(=O)C(=CNc1cccc(C)n1)C(=O)OCC>>CCOC(=O)c1cn(C)c2ncccc2c1=O,,c1ccc(Oc2ccccc2)cc1,,CCCCCC,,test
US20090030018A1,NO.O=Cc1ccc2c(c1)ncn2-c1cccc(COCc2ccccn2)c1>>ON=Cc1ccc2c(c1)ncn2-c1cccc(COCc2ccccn2)c1,,CCO,,Cl,c1ccncc1,test
US20140213578A1,NCCCN1c2ccccc2CCc2ccc(Cl)cc21.O=S(=O)(Cl)c1cccc(OC(F)(F)F)c1>>O=S(=O)(NCCCN1c2ccccc2CCc2ccc(Cl)cc21)c1cccc(OC(F)(F)F)c1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20110207701A1,N#Cc1ccc(C=O)c(Br)c1>>N#Cc1ccc(CO)c(Br)c1,,CO,,[BH4-].[Na+],,test
US20080045514A1,COc1ccccc1-c1nnc2n1N=C(c1ccc([N+](=O)[O-])c(OC)c1)CS2>>COc1cc(C2=Nn3c(nnc3-c3ccccc3OC)SC2)ccc1N,[Pd],CCOC(C)=O,,CCO,,test
US06288056B1,Cn1ccc2c1C(=O)CCN(CCCCl)C2=O.Fc1ccc(N2CCNCC2)cc1>>Cn1ccc2c1C(=O)CCN(CCCN1CCN(c3ccc(F)cc3)CC1)C2=O,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US20150225405A1,Fc1ccc2c(c1)c1c(cnn1C1CCCCO1)n2Cc1ccccc1>>Fc1ccc2c(c1)c1[nH]ncc1n2Cc1ccccc1,,CCO,,Cl,,test
US08637551B2,CCOC(OCC)c1ccccc1C(=O)c1ccc(Br)cc1ON=C(C)C>>O=Cc1ccccc1-c1noc2cc(Br)ccc12,,CCO,,Cl,O,test
US05521147,Nc1c(F)ccc2c1OCCC2.O=C1CCC(=O)N1Cl>>Nc1c(F)cc(Cl)c2c1OCCC2,,CN(C)C=O,,[Cl-].[Li+],,test
US05801180,COc1ccc2nc(COC(=O)c3ccccc3)nc(NCc3ccc4c(c3)OCO4)c2c1>>COc1ccc2nc(CO)nc(NCc3ccc4c(c3)OCO4)c2c1,[Pd],CCO,CCOC(C)=O,[H][H],,test
US20090163471A1,Cc1cc(C=O)ccc1C(=O)O>>Cc1cc(CO)ccc1C(=O)O,,CO,,[BH4-].[Na+],,test
US04345076,Cc1cc(O)c(C)cc1N.Clc1ccc(Cl)nn1>>Cc1cc(Oc2ccc(Cl)nn2)c(C)cc1N,,CS(C)=O,,[H-].[Na+],,test
US05155108,CCC(CC)(COc1ccc2nccn2n1)CS(N)(=O)=O.Cl>>CCC(CC)(COc1ccc2nccn2n1)CS(N)(=O)=O.Cl,,CO,,,,test
US20040180939A1,CC(C)(C)OC(=O)N[C@H]1CCOc2ccc(B3OC(C)(C)C(C)(C)O3)cc21.OO>>CC(C)(C)OC(=O)N[C@H]1CCOc2ccc(O)cc21,,C1CCOC1,,[Na+].[OH-],,test
US20090269301A1,CCCCCCC(=O)C(=O)OCC.NCCCn1ccnc1.O=Cc1ccccc1F>>CCCCCC1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccccc1F,,CCO,,,,test
US20150141400A1,CCOC(=O)c1cc(OC(F)(F)F)c(C=O)c(Br)c1N.CN(C(=O)OC(C)(C)C)[C@@H]1CCNC1>>CCOC(=O)c1cc(OC(F)(F)F)c(CN2CC[C@@H](N(C)C(=O)OC(C)(C)C)C2)c(Br)c1N,,ClCCl,,,,test
US20140323484A1,COc1cc(CCNC(=O)CN2CCOCC2)c(Cl)cc1[N+](=O)[O-]>>COc1cc(CCNC(=O)CN2CCOCC2)c(Cl)cc1N,[Zn],CO,,[Cl-].[NH4+],,test
US20100120785A1,Clc1nccnc1N1CCNCC1.O=Cc1cnn(CCO)c1>>OCCn1cc(CN2CCN(c3nccnc3Cl)CC2)cn1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140018533A1,CCO.CCOC(=O)C1=C(Nc2ccc(NCCN(C)C)cc2C)OCC1=O.O=Cc1c[nH]c2ncccc12>>CCOC(=O)C1=C(Nc2ccc(NCCN(C)C)cc2C)OC(=Cc2c[nH]c3ncccc23)C1=O.O=CO,,CCO,,C1CCNCC1,,test
US20070099955A1,CCC(C(=O)Cl)c1ccccc1.Cc1ccc2c(c1OC(C)C)C[C@@H](C1CCNCC1)O[C@H]2CNC=O>>CCC(C(=O)N1CCC([C@@H]2Cc3c(ccc(C)c3OC(C)C)[C@H](CNC=O)O2)CC1)c1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
US20040162435A1,CCCCCCCC(=O)OCC.CN1CCCC1CCN>>CCCCCCCC(=O)NCCC1CCCN1C,,CCOC(C)=O,O,Cc1ccccc1,[Na+].[OH-],test
US20070060754A1,CCCn1c(COCC)nc2c(N)nc3ccc(O)cc3c21.O=C(Cl)N1CCOCC1>>CCCn1c(COCC)nc2c(N)nc3ccc(OC(=O)N4CCOCC4)cc3c21,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20060148858A1,CC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO.CCOC(=O)Cn1ncc(C)c1O>>Cc1cnn(CC(=O)O)c1OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1C(C)C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US06703347B2,COC(=O)C(C)c1ccc2oc(CC(C)(C)C)nc2c1.Cc1nsc(N)c1Cl>>Cc1nsc(NC(=O)C(C)c2ccc3oc(CC(C)(C)C)nc3c2)c1Cl,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20150368210A1,CN(Cc1ccc(-c2cnc(N)c(NCc3c(Cl)cccc3Cl)n2)cc1)C1CCN(C(=O)OC(C)(C)C)[C@@H](C(=O)OC2CCCC2)C1>>CN(Cc1ccc(-c2cnc(N)c(NCc3c(Cl)cccc3Cl)n2)cc1)C1CCN[C@@H](C(=O)OC2CCCC2)C1,,CCOCC,Cl,,,test
US04762840,CC(C(=O)OC1(C)CCCCC1)c1ccc([N+](=O)[O-])cc1>>CC(C(=O)OC1(C)CCCCC1)c1ccc(N)cc1,[Pd],CCO,,[H][H],,test
US20140349987A1,CCC(C)(C)N.O=C(O)c1cc(Cl)cc(Br)c1>>CC(C)(C)NC(=O)c1cc(Cl)cc(Br)c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05053338,O=C1CCC(c2ccc(OCCCN3C(=O)c4ccccc4C3=O)cc2)=NN1>>NCCCOc1ccc(C2=NNC(=O)CC2)cc1,,CCO,,NN,O,test
US20070179122A1,COC(=O)c1cc(N2CCOCC2=O)ccc1[N+](=O)[O-]>>COC(=O)c1cc(N2CCOCC2=O)ccc1N,[Pd],CO,,,,test
US20050075378A1,CC(C)(C)OC(=O)CCc1ccc(O)cc1CN.O=C(O)c1cnccn1>>CC(C)(C)OC(=O)CCc1ccc(O)cc1CNC(=O)c1cnccn1,,ClCCl,O,ClCCCl,On1nnc2ccccc21,test
US20160244475A1,Cc1ncnc2c1ccn2[C@@H]1O[C@@H](C(=O)C#CCO[Si](C)(C)C(C)(C)C)[C@H]2OC(C)(C)O[C@H]21.NN>>Cc1ncnc2c1ccn2[C@@H]1O[C@@H](c2cc(CO[Si](C)(C)C(C)(C)C)n[nH]2)[C@H]2OC(C)(C)O[C@H]21,,CCO,,O,,test
US20040092561A1,O=C1CSC(=S)N1.O=Cc1ccc2c(c1)OCO2>>O=C1NC(=S)S/C1=C/c1ccc2c(c1)OCO2,,COCCOC,,,,test
US20140011758A1,CNC.O=C(O)C1CN(c2ccc(C3=NOC(c4cc(Cl)c(Cl)c(Cl)c4)(C(F)(F)F)C3)cc2Cl)C1>>CN(C)C(=O)C1CN(c2ccc(C3=NOC(c4cc(Cl)c(Cl)c(Cl)c4)(C(F)(F)F)C3)cc2Cl)C1,,C1CCOC1,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100190747A1,CC(C)(C)OC(=O)CCCBr.O=c1c2cc[nH]c2[nH]c(=S)n1-c1ccc(OCC(F)(F)F)cc1>>CC(C)(C)OC(=O)CCCSc1nc2[nH]ccc2c(=O)n1-c1ccc(OCC(F)(F)F)cc1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])O.[Na+],test
US20130131068A1,FC(F)c1nnc2cnccn12>>FC(F)c1nnc2n1CCNC2,[Pd],CO,,,,test
US20120071461A1,CNC1CCC2(CC1)OCCO2.O=Cc1ccccc1>>CN(Cc1ccccc1)C1CCC2(CC1)OCCO2,,ClCCl,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130203776A1,O=C(NCCCl)c1cnn2ccc(N3CCC[C@@H]3c3cc(F)c[nH]c3=O)nc12>>O=C1NCCOc2ncc(F)cc2[C@H]2CCCN2c2ccn3ncc1c3n2,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090131399A1,N.S=C1CCCCC(CCc2nc3cc(-c4ccccc4)cnc3[nH]2)N1>>NC1=NC(CCc2nc3cc(-c4ccccc4)cnc3[nH]2)CCCC1,,CO,,,,test
US20010053794A1,C=C(CCCCCCCCCC)C(N)=O.C=CC(N)=O>>C=C(CCCCCCCCCC)C(N)=O.C=CC(N)=O,,CC(C)O,,,,test
US20110313151A1,CC(=O)N[C@@H]1CC[C@@H](CC=O)CC1.c1cc2occc2c(N2CCNCC2)n1>>CC(=O)N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4occc34)CC2)CC1,CO,ClCCCl,,,,test
US20110028509A1,COC(=O)c1ccc(CNCc2ccccc2)cc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>COC(=O)c1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20120083605A1,CCOC(=O)CC(=O)OCC.Clc1nccnc1Cl>>CCOC(=O)C(C(=O)OCC)c1nccnc1Cl,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130150339A1,COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(-c4ccc(C(F)(F)F)cc4C4=CCN(C(=O)OC(C)(C)C)CC4)nccc3c2)c(OC)c1>>O=S(=O)(Nc1nccs1)c1ccc2c(-c3ccc(C(F)(F)F)cc3C3=CCNCC3)nccc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070112035A1,NO.O=Cc1cc(OCc2ccccc2)cc(C(F)(F)F)c1>>ON=Cc1cc(OCc2ccccc2)cc(C(F)(F)F)c1,,CC#N,,CCN(CC)CC,Cl,test
US20070161673A1,CC(=O)OC(C)=O.Cc1cc(-c2cc(C(=O)NC3CC3)cc(F)c2C)ncc1N>>CC(=O)Nc1cnc(-c2cc(C(=O)NC3CC3)cc(F)c2C)cc1C,,ClC(Cl)Cl,,CC(=O)[O-].[K+],,test
US20050026929A1,CCOC(=O)C(C=O)C=O.N#Cc1ccc(NN)cc1>>CCOC(=O)c1cnn(-c2ccc(C#N)cc2)c1,,CCO,,Cl,,test
US20030018021A1,CCOC(=O)C1(Cc2ccc(F)cc2)CCN(CC2CC(c3ccc4[nH]c(=O)oc4c3)=NO2)CC1>>O=C(O)C1(Cc2ccc(F)cc2)CCN(CC2CC(c3ccc4[nH]c(=O)oc4c3)=NO2)CC1,,CCO,,[Na+].[OH-],,test
US05610177,CN[C@](C)(Cc1c[nH]c2ccccc12)C(=O)O.O=C(O)C(Cc1ccc2c(c1)OCO2)Cc1ccc2c(c1)OCO2>>CC(Cc1ccc2c(c1)OCO2)(Cc1ccc2c(c1)OCO2)C(=O)N[C@](C)(Cc1c[nH]c2ccccc12)C(=O)O,,CCOC(C)=O,CN(C)C=O,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20160264554A1,CC(C)(C)OC(=O)N[C@H]1CCC[C@@H](N)C1.Clc1ncc(Cl)c(-c2cccnc2)n1>>CC(C)(C)OC(=O)N[C@H]1CCC[C@@H](Nc2ncc(Cl)c(-c3cccnc3)n2)C1,,CCOC(C)=O,CN1CCCC1=O,CCN(C(C)C)C(C)C,,test
US06599917B1,Brc1cccc(Br)n1.CCOCCO>>CCOCCOc1cccc(Br)n1,,CN(C)C=O,,O,[H-].[Na+],test
US20100273839A1,CC(C)(C)C(=O)Nc1ncc(C(=O)CBr)s1.COc1ccc(Cl)cc1NC(N)=S>>COc1ccc(Cl)cc1Nc1nc(-c2cnc(NC(=O)C(C)(C)C)s2)cs1,,CCO,,,,test
US20090035215A1,CC(C)(C)[Si](O)(c1ccc(CC(=O)O)cc1)C(C)(C)C.NCc1ccccc1>>CC(C)(C)[Si](O)(c1ccc(CC(=O)NCc2ccccc2)cc1)C(C)(C)C,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20030096828A1,CC(C)(C)ON1CCN(c2ccc(N3CCN(OC(C)(C)C)CC3=C=O)cc2)C(=C=O)C1>>c1cc(N2CCNCC2)ccc1N1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120088767A1,Cc1nc2c(C#N)cc(N3CCOCC3)cc2n1Cc1cccc2ccccc12.OO>>Cc1nc2c(C(N)=O)cc(N3CCOCC3)cc2n1Cc1cccc2ccccc12,,C1CCOC1,O,[K+].[OH-],,test
US06498165B1,Cc1cc(Cl)nc(N[C@@H](C)c2ccccc2)n1.c1ccc2[nH]cnc2c1>>Cc1cc(-n2cnc3ccccc32)nc(N[C@@H](C)c2ccccc2)n1,,CN(C)C=O,,[Na],,test
US05264438,CS(=O)(=O)Cl.Nc1ccc2[nH]c(=O)n(CCCCN3CC=C(c4ccccc4)CC3)c(=O)c2c1>>CS(=O)(=O)Nc1ccc2[nH]c(=O)n(CCCCN3CC=C(c4ccccc4)CC3)c(=O)c2c1,,CN(C)C=O,O,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20130035325A1,N#CCC(N)=O.O=CC1CCN(c2ncnc3[nH]cnc23)CC1>>N#CC(=CC1CCN(c2ncnc3[nH]cnc23)CC1)C(N)=O,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140171403A1,NC1CCN(C(=O)OCc2cc(Br)cc(C(F)(F)F)c2)CC1.O=C(Cl)CCCc1c[nH]nn1>>O=C(CCCc1c[nH]nn1)NC1CCN(C(=O)OCc2cc(Br)cc(C(F)(F)F)c2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20090005353A1,CC(C)(C)OC(=O)NC1CCC(OS(C)(=O)=O)CC1.FC(F)(F)c1ccc(S)cc1>>CC(C)(C)OC(=O)NC1CCC(Sc2ccc(C(F)(F)F)cc2)CC1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US04940710,CCn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)cc21.CN1CCN(CC2CNCCN2)CC1>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(CN4CCN(C)CC4)C3)cc21,,c1ccncc1,,,,test
US20120077993A1,CC1(C)OC(C)(C)C(=Cc2cc(Br)ccc2I)C1=O.OO>>CC1(C)OC(C)(C)C2(OC2c2cc(Br)ccc2I)C1=O,,CO,,[Li+].[OH-],,test
US20080167356A1,O=C1CCC(=O)N1Cl.ON=CCCc1c(Cl)cccc1Cl>>ON=C(Cl)CCc1c(Cl)cccc1Cl,,CN(C)C=O,,O,,test
US20080167307A1,CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCNc2ncc(Br)cn2)cs1.O=C(O)C(F)(F)F.OB(O)c1ccccc1>>CC(C)(Sc1nc(CCNc2ncc(-c3ccccc3)cn2)cs1)C(=O)O.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20160229847A1,Cn1cc(C=O)c2cc(C(F)(F)F)cc(F)c21.NCCO>>Cn1cc(NCCO)c2cc(C(F)(F)F)cc(F)c21,,CO,,O,[BH4-].[Na+],test
US20090298807A1,Cc1nc(C(=O)N2CCOC3(CCNCC3)CC2)cs1.OCCc1cccc(CBr)c1>>Cc1nc(C(=O)N2CCOC3(CCN(Cc4cccc(CCO)c4)CC3)CC2)cs1,,CC#N,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20060135578A1,CCOC(=O)CP(=O)(OCC)OCC.COc1cc(COc2cc(C=O)n(-c3ccccc3)n2)ccc1OCc1nc(-c2ccco2)oc1C>>CCOC(=O)/C=C/c1cc(OCc2ccc(OCc3nc(-c4ccco4)oc3C)c(OC)c2)nn1-c1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20040209912A1,CC(C)(C)[Si](C)(C)OCCBr.O=[N+]([O-])c1ccc2c(c1)CNCC2>>CC(C)(C)[Si](C)(C)OCCN1CCc2ccc([N+](=O)[O-])cc2C1,,CN(C)C=O,,,,test
US04806535,COC(=O)c1ccccc1C(=O)c1ccc(-n2ccnc2)cc1.NN>>O=c1[nH]nc(-c2ccc(-n3ccnc3)cc2)c2ccccc12,,CCO,,O,,test
US20120157439A1,CCCS(=O)(=O)Nc1cccc(NC(=O)c2csc3c(NCc4ccc(OC)cc4OC)ncnc23)c1F>>CCCS(=O)(=O)Nc1cccc(NC(=O)c2csc3c(N)ncnc23)c1F,,O=C(O)C(F)(F)F,,,,test
US20150119362A1,Cl.NC(=O)Cc1ccc(Nc2cc(C3=CCCC3)nc3c2CCC3)cc1>>Cl.NC(=O)Cc1ccc(Nc2cc(C3CCCC3)nc3c2CCC3)cc1,[Pd],CCO,,,,test
US04198419,CN1CCC(C#N)(c2ccccc2Sc2ccc(Cl)cc2)CC1.N#CBr>>N#CN1CCC(C#N)(c2ccccc2Sc2ccc(Cl)cc2)CC1,,ClC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US05153195,CCOC(=O)C(=O)NS(=O)(=O)c1cc2c([nH]c(=O)c(=O)n2O)c2c1CCCC2>>NS(=O)(=O)c1cc2c([nH]c(=O)c(=O)n2O)c2c1CCCC2,,Cl,,,,test
US20080312276A1,BrBr.CCCCC(=O)C=C(C)C>>CCCCC(=O)C(Br)=C(C)C,,ClCCl,,CCN(CC)CC,CCOCC,test
US20030069284A1,COc1ccc([N+](=O)[O-])cc1N=C=O.Nc1cnccn1>>COc1ccc([N+](=O)[O-])cc1NC(=O)Nc1cnccn1,,C1CCOC1,,,,test
US20090156642A1,CCOC(=O)c1cc(Sc2ccc(Cl)nc2)n(-c2ccccc2C)n1.CN>>CNC(=O)c1cc(Sc2ccc(Cl)nc2)n(-c2ccccc2C)n1,,CO,,,,test
US20100160406A1,CC(=O)c1ccc(C(=O)O)cc1.O=CC=Cc1ccccc1>>O=C(O)c1ccc(C=CC=CC(=O)c2ccccc2)cc1,,CCO,O,Cl,[Na+].[OH-],test
US20150018363A1,CON(C)C(=O)c1nc2ccc(Br)cc2n1C.C[Mg]Cl>>CC(=O)c1nc2ccc(Br)cc2n1C,,C1CCOC1,,,,test
US20160272617A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2ccc(Br)cc2)C(=O)O)CC1.Nc1ccc(-c2nc(C(F)(F)C(F)(F)C(=O)O)n[nH]2)cc1>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2ccc(Br)cc2)C(=O)Nc2ccc(-c3nc(C(F)(F)C(F)(F)C(=O)O)n[nH]3)cc2)CC1,,CCOC(C)=O,O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20080103139A1,CCOC=C(C(=O)OCC)C(=O)OCC.NCC1CCCCC1.O=C1CCCCCCC1>>O=C(O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2,,Cc1ccccc1,,,,test
US20150011773A1,CC(C)(C)OC(=O)N[C@@H](C[C@H](Cc1ccc(CCCO[Si](C)(C)C(C)(C)C)cn1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H](C[C@H](Cc1ccc(CCCO)cn1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,C1CCOC1,,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20090054425A1,CC(=O)N1CCN(c2ccc(Nc3nc(Nc4ccc5cn[nH]c5c4)c4ccn(S(=O)(=O)c5ccc(C)cc5)c4n3)cc2)CC1>>CC(=O)N1CCN(c2ccc(Nc3nc(Nc4ccc5cn[nH]c5c4)c4cc[nH]c4n3)cc2)CC1,,CO,,[K+].[OH-],,test
US20150274747A1,Cn1cc(Nc2ncc(Cl)c(NC3COC4C3OCC4N3C(=O)c4ccccc4C3=O)n2)cn1>>Cn1cc(Nc2ncc(Cl)c(NC3COC4C(N)COC34)n2)cn1,,CCO,,NN,O,test
US20140217374A1,O=C(O)c1ccsc1C(=O)O>>O=C1OC(=O)c2sccc21,,CC(=O)OC(C)=O,,,,test
US20090137790A1,COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(NC(C)=O)ncnc43)[C@H](O)[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1.N#CCCOCCl>>COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(NC(C)=O)ncnc43)[C@H](OCOCCC#N)[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1,,ClCCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20050065185A1,CC(C)(C)OC(=O)N1CCC[C@@H]1CO.Oc1cccc2[nH]ccc12>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cccc2[nH]ccc12,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160039783A1,O=C1CCC(=O)N1Cl.O=Cc1cscc1Br>>O=Cc1csc(Cl)c1Br,,CN(C)C=O,,O,,test
US03988457,ClCc1ccc2ccccc2c1.c1cnc(N2CCNCC2)nc1>>c1cnc(N2CCN(Cc3ccc4ccccc4c3)CC2)nc1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20060063759A1,Nc1cc(C=C2c3ccccc3CCc3ccccc32)ccc1O.O=C(Cl)Oc1ccccc1>>O=c1[nH]c2cc(C=C3c4ccccc4CCc4ccccc43)ccc2o1,,CO,O,Cl,[Na+].[OH-],test
US04284631,CCOC(=O)C(=NOCc1ccc(C)cc1)C(=O)CCl.NC(N)=S>>CCOC(=O)C(=NOCc1ccc(C)cc1)c1csc(N)n1,,CCO,,O,CC(=O)[O-].[Na+],test
US20090082440A1,COc1ccc(COC(C(=O)O)C(C)(C)COS(=O)(=O)CCCCl)cc1.OCCN1CCOCC1>>COc1ccc(COC(C(=O)OCCN2CCOCC2)C(C)(C)COS(=O)(=O)CCCCl)cc1,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20040259912A1,COC(=O)c1cc(N)ccc1OC(c1ccc(F)cc1)c1ccccc1Cl.COc1ccc(N=C=O)cc1OC>>COC(=O)c1cc(NC(=O)Nc2ccc(OC)c(OC)c2)ccc1OC(c1ccc(F)cc1)c1ccccc1Cl,,C1CCOC1,,,,test
US20080176829A1,CC(C)(C)OC(=O)N1CCOc2ccc3[nH]ccc3c2C1.O=S(=O)(Cl)c1cc2ccccc2s1>>O=S(=O)(c1cc2ccccc2s1)n1ccc2c3c(ccc21)OCCNC3,,CO,N,CN(C)C=O,[H-].[Na+],test
US20100137308A1,CNC.NS(=O)(=O)c1ccc(C(=O)O)cc1>>CN(C)C(=O)c1ccc(S(N)(=O)=O)cc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20130317023A1,Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F.O=S(=O)(Cl)c1ccc(Cl)cc1F>>O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F)c1ccc(Cl)cc1F,,ClCCl,,c1ccncc1,,test
US05721227,CCOCO[C@]12C=CC(=O)[C@@]1(C)CC[C@H]1[C@H]2CC=C2C[C@@H](OC(C)=O)CC[C@@]21C>>CCOCO[C@]12C=CC(=O)[C@@]1(C)CC[C@H]1[C@H]2CC=C2C[C@@H](O)CC[C@@]21C,,CO,O,[Na+].[OH-],,test
US20110312969A1,CCOC(=O)c1cccc(OCCCn2c(=N)n(Cc3ccc(N4CCN(Cc5ccccc5-c5ccccc5)CC4)cc3)c3ccccc32)c1>>N=c1n(CCCOc2cccc(C(=O)O)c2)c2ccccc2n1Cc1ccc(N2CCN(Cc3ccccc3-c3ccccc3)CC2)cc1,,CO,,[Na+].[OH-],,test
US09376441B2,C[C@@H](Oc1nc(-c2ccc3c(c2)NC(=O)C32CCNCC2)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>C[C@@H](Oc1nc(-c2ccc3c(c2)NC(=O)C32CCN(CC(F)(F)F)CC2)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1,,CN(C)C=O,,,,test
US20110021493A1,CC(C)(C)OC(=O)Nc1cc(O)c(Cl)c(Cl)c1.Cl>>Cl.Nc1cc(O)c(Cl)c(Cl)c1,,CC(C)O,,C1COCCO1,,test
US20110028492A1,Brc1cccc(Br)n1.N[C@@H]1CC12CCOCC2>>Brc1cccc(N[C@@H]2CC23CCOCC3)n1,,CCOC(C)=O,CN1CCCC1=O,Cl,O=C([O-])[O-].[K+].[K+],test
US04837217,CC(C)(C)c1ccc(CCl)s1.Cc1c(S)cnn(C(C)(C)C)c1=O>>Cc1c(SCc2ccc(C(C)(C)C)s2)cnn(C(C)(C)C)c1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20140187533A1,CC(C)(C)OC(=O)N1CCN(Cc2nc3c(Cl)cc(Cl)cc3[nH]2)C(=O)C1.CC1(C)CO1>>CC(C)(O)Cn1c(CN2CCNCC2=O)nc2c(Cl)cc(Cl)cc21,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050197340A1,Cn1c(=O)c(Oc2ccc(F)cc2F)cc2c1c(I)nn2C(=O)OC(C)(C)C.OB(O)c1ccccc1Cl>>Cn1c(=O)c(Oc2ccc(F)cc2F)cc2c1c(-c1ccccc1Cl)nn2C(=O)OC(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,c1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20120101110A1,N#Cc1ccnc(Cl)c1.O=C1N(Cc2c[nH]c3ccccc23)CCCC12CCNCC2>>N#Cc1ccnc(N2CCC3(CCCN(Cc4c[nH]c5ccccc45)C3=O)CC2)c1,CN(C)c1ccncc1,CCO,,CCN(C(C)C)C(C)C,,test
US20100305096A1,C1CN(C2CCOCC2)CCN1.CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C=O)n(C)c2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCN(C4CCOCC4)CC3)n(C)c2n1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100063081A1,CC(C)(C)OC(=O)N1CCC(OCCO)CC1>>CC(C)(C)OC(=O)N1CCC(OCC=O)CC1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4cccc(F)c4)nc(Cl)c3n2)cc1.Nc1ccc(N2CCOCC2)cc1>>Fc1cccc(-c2nc(Nc3ccc(N4CCOCC4)cc3)c3[nH]ncc3n2)c1,C1COCCO1,CO,,Cl,,test
US20100311730A1,CC(C)(O)C#Cc1cnc(Nc2cnc(C#N)cn2)cc1NCC1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(O)C#Cc1cnc(Nc2cnc(C#N)cn2)cc1NCC1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120040954A1,COC(=O)c1ccc(NC(C)=O)c(C#CCCOC2CCCCO2)c1>>COC(=O)c1ccc2[nH]c(CCOC3CCCCO3)cc2c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20070197532A1,COCC(C)Oc1ccc(O)cc1-c1cc(OC)n[nH]1.OCCc1ccsc1>>COCC(C)Oc1ccc(OCCc2ccsc2)cc1-c1cc(OC)n[nH]1,,Cc1ccccc1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20110172237A1,O=C(CBr)Nc1ccc(C(F)(F)F)nn1.O=C(O[C@H]1CN2CCC1CC2)C1(c2ccccc2)CCCCCC1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C1(c3ccccc3)CCCCCC1)C2)Nc1ccc(C(F)(F)F)nn1.[Br-],,CC#N,,,,test
US20110281842A1,CCCC[Sn](Cl)(CCCC)CCCC.COc1ccc(CNC2(c3nccs3)CCC2)cc1>>CCCC[Sn](CCCC)(CCCC)c1cnc(C2(NCc3ccc(OC)cc3)CCC2)s1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US04472193,O=P(Cl)(Cl)Cl.O=c1ccc2cc(Cl)ncc2[nH]1>>Clc1cc2ccc(Cl)nc2cn1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20090306403A1,COc1ccc(CN)cc1.CS(=O)(=O)CC=CCS(C)(=O)=O>>COc1ccc(CN2CC=CC2)cc1,,ClCCl,,,,test
US05217980,CCOC(=O)N1CCC(Nc2nc3ccccc3[nH]2)CC1.Cc1ncc(CBr)o1>>CCOC(=O)N1CCC(Nc2nc3ccccc3n2Cc2cnc(C)o2)CC1,,O,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US04882085,CCCCCCCCCCCCOC(C)COS(=O)(=O)c1ccc(C)cc1.Oc1ccc(O)cc1>>CCCCCCCCCCCCOC(C)COc1ccc(O)cc1,,CCO,,[K+].[OH-],,test
US20110311474A1,Cc1ccc(S(=O)(=O)n2ccc3nc(N(CC(=O)C4CC(N(Cc5ccccc5)Cc5ccccc5)CC4C)C(=O)OC(C)(C)C)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3nc(NCC(=O)C4CC(N(Cc5ccccc5)Cc5ccccc5)CC4C)cnc32)cc1,,Cl,,,,test
US20150038528A1,CCCCOC(=O)c1nc(C#N)c2ccc(Oc3c(C)cccc3C)cc2c1O.NCCCC(=O)O>>Cc1cccc(C)c1Oc1ccc2c(C#N)nc(C(=O)NCCCC(=O)O)c(O)c2c1,,COCCO,,C[O-].[Na+],,test
US04163846,CC(=O)Cl.Cn1nc2nc(C(C)(C)C)[nH]c(=O)c2c1N>>CC(=O)Nc1c2c(=O)[nH]c(C(C)(C)C)nc2nn1C,,c1ccncc1,,,,test
US05190934,CC(C)=CNC(=O)OC(C)(C)C.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)OC(=O)NC1OC1(C)C,,ClC(Cl)Cl,,,,test
US20100298302A1,CCOC(=O)c1cccc2c1nc(Cl)c1cncn12.Nc1ccccc1F>>CCOC(=O)c1cccc2c1nc(Nc1ccccc1F)c1cncn12,,CN1CCCC1=O,O,,,test
US20070082912A1,CC(=O)CCC(=O)c1cc(C)ccc1OCc1ccc(F)cc1.Nc1cc(C(=O)O)c2ccccc2c1>>Cc1ccc(OCc2ccc(F)cc2)c(-c2ccc(C)n2-c2cc(C(=O)O)c3ccccc3c2)c1,,CCOC(C)=O,CN1CCCC1=O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080221114A1,C[C@H]1CCCNC1.O=C(O)[C@@H]1Cc2ccccc2N1c1ccc(=O)n(Cc2ccccc2)n1>>C[C@H]1CCCN(C(=O)[C@@H]2Cc3ccccc3N2c2ccc(=O)n(Cc3ccccc3)n2)C1,,c1ccncc1,,CCN=C=NCCCN(C)C,Cl,test
US20120208817A1,CCOc1cc(C=O)cc([N+](=O)[O-])c1O.NC(N)=O.O=C(Cc1ccccc1)c1ccc(-c2ccccc2)cc1>>CCOc1cc(C2NC(=O)NC(c3ccc(-c4ccccc4)cc3)=C2c2ccccc2)cc([N+](=O)[O-])c1O,,CCO,,Cl,,test
US08987312B2,COC(=O)c1cccc(-c2nnc(C(=O)CCCCCCc3ccccc3)s2)n1>>O=C(O)c1cccc(-c2nnc(C(=O)CCCCCCc3ccccc3)s2)n1,,CC(=O)O,CCOC(C)=O,,,test
US04061656,COc1cc(C)c(CO)s1.ClC(Cl)(Cl)Cl.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>COc1cc(C)c(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)s1.[Cl-],,Cc1ccccc1,,,,test
US20060252777A1,COc1cc2nccc(Cl)c2cc1OC.Oc1ccc(-c2ccc(Oc3ccccc3)nn2)cc1F>>COc1cc2nccc(Oc3ccc(-c4ccc(Oc5ccccc5)nn4)cc3F)c2cc1OC,CN(C)c1ccncc1,Cc1ccccc1,,,,test
US20110207947A1,CCCCCCCC(O)/C=C/C(=C/C(=O)OC)C(=O)OC.O=C(OO)c1cccc(Cl)c1>>CCCCCCCC(O)C1OC1/C(=C/C(=O)OC)C(=O)OC,,ClC(Cl)(Cl)Cl,,,,test
US04709047,C=CCC12C=CC(C1)C1C(=O)OC(=O)C12.NO>>C=CCC12C=CC(C1)C(C(=O)O)C2C(O)=NO,,O,,Cl,[Na+].[OH-],test
US20040122244A1,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)O)c2)=C(C)C1=O.Nc1ccnc(Cl)c1>>COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)Nc3ccnc(Cl)c3)c2)=C(C)C1=O,,ClCCl,,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US20160194302A1,CCOC(=O)Cn1ccnc1CCC(=O)N1CCC(N2CCCCC2)CC1>>O=C(O)Cn1ccnc1CCC(=O)N1CCC(N2CCCCC2)CC1,,O,,,,test
US20130116250A1,Cn1c(=O)n(Cc2ccc(F)cc2)c(=O)c2cc(C(=O)c3nc(Br)c4ccccn34)ccc21.OB(O)c1cccnc1>>Cn1c(=O)n(Cc2ccc(F)cc2)c(=O)c2cc(C(=O)c3nc(-c4cccnc4)c4ccccn34)ccc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20080142454A1,NC1CCC=CCCC1.[N-]=[N+]=Nc1ccc(C(=O)O)cc1>>[N-]=[N+]=Nc1ccc(C(=O)NC2CCC=CCCC2)cc1,,C1CCOC1,,CCN(CC)CC,O=S(Cl)Cl,test
US20140018347A1,CC(=O)Nc1nc2cc(B3OC(C)(C)C(C)(C)O3)cnc2s1.CC[C@@H](C)S(=O)N[C@H](C)c1nc(C)c(C(C)C)c(N2CCOc3ccc(Br)cc3C2)n1>>CC[C@@H](C)S(=O)N[C@H](C)c1nc(C)c(C(C)C)c(N2CCOc3ccc(-c4cnc5sc(N)nc5c4)cc3C2)n1,,C1COCCO1,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20050171130A1,CCC(O)C(C)(C)C.Clc1cc(Cl)ncn1>>CCC(Oc1cc(Cl)ncn1)C(C)(C)C,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20060217372A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Oc1ccc(CNCCc2ccccc2)cc1>>CC(C)(C)OC(=O)N(CCc1ccccc1)Cc1ccc(O)cc1,,ClCCl,,,,test
US20100120740A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](CO)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](CO)C(=O)O,,C1COCCO1,,[Na+].[OH-],,test
US20080004323A1,BrC(Br)(Br)Br.O=C(C=CSc1ccccc1)NOCc1ccccc1>>BrC(C=CSc1ccccc1)=NOCc1ccccc1,,CC#N,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20160272645A1,C=CC(=O)Cl.Nc1ncnc2c1c(-c1ccc(Cl)c(O)c1)nn2CCNCc1ccco1>>C=CC(=O)N(CCn1nc(-c2ccc(Cl)c(O)c2)c2c(N)ncnc21)Cc1ccco1,,ClCCl,,,,test
US20040024010A1,COc1ccccc1-c1ccc2c(c1)NC(=O)C2.O=Cc1[nH]c2c(c1CCC(=O)O)CCCC2>>COc1ccccc1-c1ccc2c(c1)NC(=O)C2=Cc1[nH]c2c(c1CCC(=O)O)CCCC2,C1CCNCC1,CCO,,,,test
US20150225375A1,CC(C)(C)OC(=O)N1CCC(C=O)(Cc2ccc(F)cc2)CC1.N[C@@H]1C[C@H]1c1ccccc1>>CC(C)(C)OC(=O)N1CCC(CN[C@@H]2C[C@H]2c2ccccc2)(Cc2ccc(F)cc2)CC1,,ClCCCl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20120122764A1,CC(C)(C)OC(=O)NCC(Cc1ccc(Br)cc1)C(=O)OCc1ccccc1.OB(O)c1ccccc1>>CC(C)(C)OC(=O)NCC(Cc1ccc(-c2ccccc2)cc1)C(=O)OCc1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20160237091A1,O=[N+]([O-])c1cc2c(cnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1NCc1ccccc1>>Nc1cc2c(cnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1NCc1ccccc1,[Ni],C1CCOC1,CO,,,test
US20100160280A1,CC(=O)N1CCC(c2nccnc2Cl)CC1.Oc1ccc(Nc2ccccn2)cc1F>>CC(=O)N1CCC(c2nccnc2Oc2ccc(Nc3ccccn3)cc2F)CC1,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130303533A1,CCOC=C(C#N)C#N.NNCCO>>N#Cc1cnn(CCO)c1N,,CCO,,,,test
US03998834,CC(C)Br.COCC1(Nc2ccccc2)CCNCC1>>COCC1(Nc2ccccc2)CCN(C(C)C)CC1,,CC(=O)N(C)C,,CCN(CC)CC,,test
US20120264749A1,COC(=O)c1ccc(OC(C)C)cc1F>>CC(C)Oc1ccc(C(=O)O)c(F)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20130324579A1,CI.COc1ccc2c(CCBr)c[nH]c2c1>>COc1ccc2c(CCBr)cn(C)c2c1,,C1CCOC1,,[H-].[Na+],,test
US20070259864A1,N#Cc1ccc(CCCBr)cc1.NCCO>>N#Cc1ccc(CCCNCCO)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040049086A1,Cc1cc(C2CCC(c3ccc(O)cc3)CC2)ccc1O>>Cc1cc([C@@H]2CC[C@@H](c3ccc(O)cc3)CC2)ccc1O,,CO,,,,test
US20060094735A1,CC(C)C(NCC(=O)CCN1C(=O)c2ccccc2C1=O)c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1.Cc1ccc(C(=O)Cl)cc1>>Cc1ccc(C(=O)N(CC(=O)CCN2C(=O)c3ccccc3C2=O)C(c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1,,ClCCl,,CCN(CC)CC,,test
US06114325,CCCCCCCCCCCCCCCCCCNC(=O)c1ccccc1COC(=O)N1CCN(C)CC1.Cl>>CCCCCCCCCCCCCCCCCCNC(=O)c1ccccc1COC(=O)N1CCN(C)CC1.Cl,,CCOC(C)=O,,,,test
US04980287,CC(C)OC(=O)Nc1cc(N)ccc1C(=O)O.O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1>>CC(C)OC(=O)Nc1cc(NC(=O)[C@@H]2CCCN2C(=O)OCc2ccccc2)ccc1C(=O)O,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20080139639A1,CN.Cl.O=Cc1cc(-c2ccccc2)n(S(=O)(=O)c2cccc([N+](=O)[O-])c2)c1>>CNCc1cc(-c2ccccc2)n(S(=O)(=O)c2cccc([N+](=O)[O-])c2)c1.Cl,,CO,,[BH4-].[Na+],,test
US20120015957A1,CC(C)(C)OC(=O)N1CCN(c2ccc(C(=N)NO)cc2F)CC1.CCC(=O)Cl>>CCc1nc(-c2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)c(F)c2)no1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20110190489A1,CCc1c(-c2ccc(C3(C)OCCO3)cc2)n(COCC[Si](C)(C)C)c2ncc3cnc(C)n3c12>>CCc1c(-c2ccc(C(C)=O)cc2)n(COCC[Si](C)(C)C)c2ncc3cnc(C)n3c12,,CC(C)=O,,Cl,,test
US04079066,CN(C)CCOc1ccc2c(c1)OC(C)(C)CC2=O.Fc1ccc([Mg]Br)c2ccccc12>>CN(C)CCOc1ccc2c(c1)OC(C)(C)C=C2c1ccc(F)c2ccccc12,,C1CCOC1,,,,test
US20120295915A1,O=C(C1CC1)N1CC[C@@H](CNc2ncnc(Cl)c2[N+](=O)[O-])C1>>Nc1c(Cl)ncnc1NC[C@@H]1CCN(C(=O)C2CC2)C1,[Fe],CC(=O)O,,,,test
US20110319380A1,CI.O=c1c2ccc(Br)cc2nc2n1CCNC2>>CN1CCn2c(nc3cc(Br)ccc3c2=O)C1,,CC(C)=O,,,,test
US04378371,CN=C=O.Cc1cc(C)c2c(c1O)CC(C)C2(C)C>>CNC(=O)Oc1c(C)cc(C)c2c1CC(C)C2(C)C,CCN(CC)CC,O,,,,test
US04057573,COC(=O)C1CCc2ccc(OC)cc21.O=C(Cl)c1ccccc1>>COC(=O)C1CCc2cc(C(=O)c3ccccc3)c(O)cc21,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20080269059A1,C=COCCCC.O=C(Cl)C(F)(F)C(F)(F)C(F)(F)F>>CCCCOC=CC(=O)C(F)(F)C(F)(F)C(F)(F)F,,ClCCl,,O,c1ccncc1,test
US06576637B1,COC(=O)CC(NC(=O)CNC(=O)CCCNc1cc(C)ccn1)c1ccccc1[N+](=O)[O-]>>Cc1ccnc(NCCCC(=O)NCC(=O)NC(CC(=O)O)c2ccccc2[N+](=O)[O-])c1,,C1COCCO1,,[Na+].[OH-],,test
US20080076924A1,CC(C)C1CN(c2ccc(Cl)nn2)CCN1>>CC(C)C1CN(c2cccnn2)CCN1,[Pd],CO,,O=C[O-].[NH4+],,test
US20150239847A1,Fc1ncnc(F)c1F.Nc1cc[nH]n1>>Nc1ccn(-c2ncnc(F)c2F)n1,,CC#N,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US04423047,Brc1cnc(SCc2cccs2)nc1.O=C(OO)c1cccc(Cl)c1>>O=S(Cc1cccs1)c1ncc(Br)cn1,,ClCCl,,,,test
US04436746,COC(=O)CCCCn1c(-n2ccnc2)c(C)c2ccccc21.N>>Cc1c(-n2ccnc2)n(CCCCC(N)=O)c2ccccc12,,CCCCO,,,,test
US20100093730A1,FC(F)(F)c1cccc(CN2CCNCC2)c1.O=C(O)CN1CCC(c2ccc(F)cc2)(c2ccc(F)cc2)C1=O>>O=C(CN1CCC(c2ccc(F)cc2)(c2ccc(F)cc2)C1=O)N1CCN(Cc2cccc(C(F)(F)F)c2)CC1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20040037022A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(C[C@@H](CO)NC[C@H](O)c2cccc(Cl)c2)cc1>>CC(C)(C)OC(=O)N(C[C@H](O)c1cccc(Cl)c1)[C@H](CO)Cc1ccc(N)cc1,,C1CCOC1,,,,test
US20110039852A1,CCNCc1cc(C(F)(F)F)ccc1-c1cc([C@@H](C)C(=O)O)cc(C(F)(F)F)c1.CO>>CCNCc1cc(C(F)(F)F)ccc1-c1cc([C@@H](C)C(=O)OC)cc(C(F)(F)F)c1,O=S(=O)(O)O,,,,,test
US20110015157A1,CS(N)(=O)=O.C[C@@H](c1cccc(Br)c1)N1CC[C@](CCCOS(C)(=O)=O)(c2ccc(F)cc2)OC1=O>>C[C@@H](c1cccc(Br)c1)N1CC[C@](CCCNS(C)(=O)=O)(c2ccc(F)cc2)OC1=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090240058A1,CCOC(=O)C(C)(C)Oc1ccc(C(=O)CCc2cn(-c3ccc(C(F)(F)F)cc3)nc2C(C)C)cc1C>>Cc1cc(C(=O)CCc2cn(-c3ccc(C(F)(F)F)cc3)nc2C(C)C)ccc1OC(C)(C)C(=O)O,,CCO,O,Cl,[Li+].[OH-],test
US20090137609A1,CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc(-c2cncc(CC(=O)OC)c2)c(C)c1>>CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc(-c2cncc(CC(=O)O)c2)c(C)c1,,CO,,[Na+].[OH-],[Cl-].[NH4+],test
US05075324,CCOC(=O)C1=C(CCC(OC=O)c2ccccc2)NC(C)=C(C(=O)OC)C1c1cccc([N+](=O)[O-])c1>>CCOC(=O)C1=C(C)NC(CCC(O)c2ccccc2)=C(C(=O)OC)C1c1cccc([N+](=O)[O-])c1,,CO,,O=C([O-])O.[Na+],,test
US20110263611A1,C[S@](=N)(=O)c1ccccc1.O=C(O)c1cncc(Br)c1>>C[S@@](=O)(=NC(=O)c1cncc(Br)c1)c1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20100324106A1,Fc1cc(OCc2ccccc2)c(F)cc1Br.c1ccc(COc2cccc3[nH]ccc23)cc1>>Fc1cc(-n2ccc3c(OCc4ccccc4)cccc32)c(F)cc1OCc1ccccc1,,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20140135309A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.O=[N+]([O-])c1ccc(F)cc1O[C@@H]1CO[C@@H]2[C@@H](O)CO[C@H]12>>O=[N+]([O-])c1ccc(F)cc1O[C@@H]1CO[C@@H]2[C@@H](OS(=O)(=O)C(F)(F)F)CO[C@H]12,,ClCCl,,c1ccncc1,,test
US20150119412A1,CCc1c(C(=O)OC)ccn(C2CCN(Cc3cc(C4CC4)c(C4CC4)c(F)c3OC(C)C)CC2)c1=O>>CCc1c(C(=O)O)ccn(C2CCN(Cc3cc(C4CC4)c(C4CC4)c(F)c3OC(C)C)CC2)c1=O,,CCO,,[Na+].[OH-],,test
US20150111877A1,Cc1cccc(S(=O)(=O)N2CC(N(Cc3ccccc3)Cc3ccccc3)COc3ncc(N)cc32)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>Cc1cccc(S(=O)(=O)N2CC(N(Cc3ccccc3)Cc3ccccc3)COc3ncc(NC(=O)C(F)(F)F)cc32)c1,,CCOC(C)=O,ClCCl,O,,test
US20120088767A1,COC(=O)c1cc(N2CCOCC2)cc2nc(C(F)(F)F)[nH]c12.Cc1c(CBr)cccc1C(F)(F)F>>COC(=O)c1cc(N2CCOCC2)cc2c1nc(C(F)(F)F)n2Cc1cccc(C(F)(F)F)c1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110021522A1,Nc1cccc(-c2ccc3nonc3c2)c1.O=C(O)c1cc2cccc(O)c2oc1=O>>O=C(Nc1cccc(-c2ccc3nonc3c2)c1)c1cc2cccc(O)c2oc1=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100093731A1,COc1cc(Nc2ncnc(Cl)n2)ccc1-n1cnc(C)c1.Oc1ccccc1C(F)(F)F>>COc1cc(Nc2ncnc(Oc3ccccc3C(F)(F)F)n2)ccc1-n1cnc(C)c1,,CCOC(C)=O,,,,test
US20140121198A1,CC(C)(C)OC(=O)NS(C)(=O)=O.ClCc1nc2cnc3ccsc3c2n1[C@H]1CC2CCC1C2>>CC(C)(C)OC(=O)N(Cc1nc2cnc3ccsc3c2n1[C@H]1CC2CCC1C2)S(C)(=O)=O,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20060122251A1,C=O.C[C@@H](Cn1ncc2ccc(O)cc21)NC(=O)OCc1ccccc1>>C[C@@H](Cn1ncc2ccc(O)c(CO)c21)NC(=O)OCc1ccccc1,,C1CCOC1,,[Na+].[OH-],,test
US20090247534A1,CC(C)COC(=O)Cl.N=C(CC1CCC(c2ccc(-c3ccc(Nc4ccc(C(F)(F)F)nc4)nn3)cc2)CC1)NO>>CC(C)COC(=O)N/C(CC1CCC(c2ccc(-c3ccc(Nc4ccc(C(F)(F)F)nc4)nn3)cc2)CC1)=N\O,,CN(C)C=O,,c1ccncc1,,test
US20030195259A1,CCCc1cc(C(=O)CC)ccc1-c1cc(OCc2ccc(CO)c(CO)c2)ccc1C.CC[Mg]Br>>CCCc1cc(C(O)(CC)CC)ccc1-c1cc(OCc2ccc(CO)c(CO)c2)ccc1C,,C1CCOC1,,[Cl-].[NH4+],,test
US20080004309A1,CCOC(=O)c1sc(-c2ccc(Oc3ccccc3)cc2)nc1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1sc(-c2ccc(Oc3ccccc3)cc2)nc1CBr,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20030078277A1,CC(=O)C1CCOC1=O.Cc1cc(N)n(-c2c(Cl)cc(Cl)cc2Cl)n1>>C/C(Nc1cc(C)nn1-c1c(Cl)cc(Cl)cc1Cl)=C1/CCOC1=O,,CCO,,,,test
US20140213592A1,ClC=C(Cl)n1cnc2ccccc21>>C#Cn1cnc2ccccc21,,C1CCOC1,,,,test
US20030013720A1,CC(C)(C)OC(=O)N1CCC(C#N)(c2ccc(I)cc2)CC1>>N#CC1(c2ccc(I)cc2)CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110105462A1,CCCN.Cc1ccc(S(=O)(=O)OCC2COc3ccc(Cl)cc3O2)cc1>>CCCNCC1COc2ccc(Cl)cc2O1,,CC#N,,,,test
US20020037875A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.OCCCc1ccc(O)cc1>>CC(C)(C)[Si](OCCCc1ccc(O)cc1)(c1ccccc1)c1ccccc1,,CN(C)C=O,,c1c[nH]cn1,,test
US20040138462A1,O=C([O-])COc1ccc(S(=O)(=O)c2ccc(CCNC[C@H](O)c3cccc(Cl)c3)cc2)cc1>>O=C(O)COc1ccc(S(=O)(=O)c2ccc(CCNC[C@H](O)c3cccc(Cl)c3)cc2)cc1,,CO,,Cl,,test
US05612323,CO.O=[PH](O)c1ccccc1>>CO[PH](=O)c1ccccc1,CN(C)c1ccncc1,C1CCOC1,,CCN=C=NCCCN(C)C,,test
US20040192686A1,CNC.CS(=O)(=O)Cl.[O-][n+]1nc(CCCO)nc2ccccc21>>CN(C)CCCc1nc2ccccc2[n+]([O-])n1.Cl,,ClCCl,,CCN(CC)CC,,test
US20060276449A1,CN(C)C(=O)[C@@H]1C[C@@H](F)CN1C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CN(C)C(=O)[C@@H]1C[C@@H](F)CN1.O=C(O)C(F)(F)F,,ClC(Cl)Cl,,,,test
US20040063699A1,O=C(CCN1CCN(Cc2ccccc2)CC1)Nc1ccc2c(c1)CCN(C(=O)C(F)(F)F)CC2>>O=C(CCN1CCN(Cc2ccccc2)CC1)Nc1ccc2c(c1)CCNCC2,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20120022080A1,N#Cc1ccc(B(O)O)cc1.O=S(=O)(OC1=CCOCC1)C(F)(F)F>>N#Cc1ccc(C2=CCOCC2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],test
US20110144334A1,CN.Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(=O)Cl>>CNC(=O)c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1C,,C1CCOC1,,,,test
US20160009701A1,CC(=O)Cl.Cc1noc(C)c1-c1cc(C(N)=O)c2c(c1)c1ccc(N)cc1n2CC1CC1>>CC(=O)Nc1ccc2c3cc(-c4c(C)noc4C)cc(C(N)=O)c3n(CC3CC3)c2c1,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20110301355A1,C1CCNC1.O=C=Nc1ccc(Cl)cc1Cl>>O=C(Nc1ccc(Cl)cc1Cl)N1CCCC1,,c1ccccc1,,,,test
US20150266870A1,CCN(CC)CCO.Nc1ncc(O)cn1>>CCN(CC)CCOc1cnc(N)nc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090197862A1,ClCCl.Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2cccc(-c3cn[nH]c3)c2s1.O=C(O)C(F)(F)F>>Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2cccc(-c3cc[nH]c3)c2s1.O=C(O)C(F)(F)F,,ClCCl,,Cl,Cl,test
US20140275528A1,Cn1c(N)c(NC(=O)C=Cc2ccccc2)c(=O)n(C)c1=O>>Cn1c(=O)c2[nH]c(/C=C/c3ccccc3)nc2n(C)c1=O,,CCO,,[Na+].[OH-],,test
US20060009453A1,Cc1ccc(NC(=O)OC(C)(C)C)cc1Nc1ncccc1-c1ccncn1>>Cc1ccc(N)cc1Nc1ncccc1-c1ccncn1,,CCOC(C)=O,,ClCCl,O=C(O)C(F)(F)F,test
US20120077799A1,COc1cccc(-c2ccc(C3=CC=CN4CCS(=O)(=O)N=C34)cc2)c1>>COc1cccc(-c2ccc(C3CCCN4CCS(=O)(=O)N=C34)cc2)c1,O=[Pt]=O,C1CCOC1,CO,,,test
US05880270,CCOC(C)=NOCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21>>NOCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21,,CCO,,Cl,,test
US05741789,CN(C)C=O.COC(C)(C)C.C[O-].Oc1cccc2[nH]ccc12>>c1cc(OC[C@@H]2CO2)c2cc[nH]c2c1,,CN(C)C=O,,O,,test
US05872138,BrCC1CCCCC1.CCCc1cc(C(=O)OC)ccc1O>>CCCc1cc(C(=O)OC)ccc1OCC1CCCCC1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080039459A1,CC(=O)OCC(=O)Cl.CC1(C)OB(c2cccc3[nH]ncc23)OC1(C)C.CNCc1cc2nc(Cl)nc(N3CCOCC3)c2s1>>CN(Cc1cc2nc(-c3cccc4[nH]ncc34)nc(N3CCOCC3)c2s1)C(=O)CO,,CO,,C1CCOC1,[Li+].[OH-],test
US20140275003A1,CC1(C)CNCCO1.Clc1cc(Cl)nc(N2CCOCC2)n1>>CC1(C)CN(c2cc(Cl)nc(N3CCOCC3)n2)CCO1,,CCO,,CCN(CC)CC,,test
US20110281884A1,CC(=O)c1cc(Cl)c2ccnn2c1-c1cccc(F)c1.[NH4+]>>CC(N)c1cc(Cl)c2ccnn2c1-c1cccc(F)c1,,CO,,[BH3-]C#N.[Na+],,test
US20160113912A1,CCOC(=O)c1nn(-c2ccc(OC)cc2)c2c1CCN(c1ccc(N)cc1)C2=O.NC=O>>COc1ccc(-n2nc(C(N)=O)c3c2C(=O)N(c2ccc(N)cc2)CC3)cc1,,CN(C)C=O,O,CO,C[O-].[Na+],test
US04806555,OC(CCCl)COc1ccc(F)cc1.c1ccc(N2CCNCC2)nc1>>OC(CCN1CCN(c2ccccn2)CC1)COc1ccc(F)cc1,,CCCCO,,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US20090143358A1,N.O=C(O)c1ccc(F)c(C2CC2)c1>>NC(=O)c1ccc(F)c(C2CC2)c1,,C1CCOC1,,,,test
US20120214762A1,C#CC(C)(O)c1ccc(F)cn1.Nc1nccc(-n2c(OCCO)nc3ccc(Br)cc32)n1>>CC(O)(C#Cc1ccc2nc(OCCO)n(-c3ccnc(N)n3)c2c1)c1ccc(F)cn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CS(C)=O,,CCN(CC)CC,,test
US20040229861A1,COCCBr.O=C1CCCC(c2ccccc2)CN1>>COCCN1CC(c2ccccc2)CCCC1=O,,CN(C)C=O,,O,[H-].[Na+],test
US20100105686A1,CC(C)(C)OC(=O)N1CCC(CNC(=O)CN)CC1.O=C(O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccc(Cl)cc2Cl)cc1>>CC(C)(C)OC(=O)N1CCC(CNC(=O)CNC(=O)c2ccc(S(=O)(=O)Nc3ccccc3Oc3ccc(Cl)cc3Cl)cc2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160068482A1,O=C1CCCCC1.OCCCO>>C1CCC2(CC1)OCCCO2,II,CCOCC,,,,test
US05834463,CC1=Nc2ccccc2N(Cc2ccccc2)C(=O)C1.O=Cc1ccncc1>>O=C1CC(/C=C/c2ccncc2)=Nc2ccccc2N1Cc1ccccc1,,CCOCC,,,,test
US20140350262A1,Cc1nc2c(cc1[N+](=O)[O-])CC(NCCc1ccccc1)CC2>>CN(CCc1ccccc1)C1CCc2ncc(N)cc2C1,[Pd],,,CCO,[H][H],test
US03993646,CC1(CBr)S[C@@H]2C(NC(=O)Cc3cccs3)C(=O)N2C1C(=O)OCC(Cl)(Cl)Cl>>CC1=C(C(=O)OCC(Cl)(Cl)Cl)N2C(=O)C(NC(=O)Cc3cccs3)[C@H]2SC1,,c1ccccc1,,c1ccncc1,,test
US04788206,CCCCCC/C(=C\C=C\C(=O)OC)c1ccc(OC)cc1>>CCCCCC/C(=C\C=C\C(=O)O)c1ccc(OC)cc1,,CO,,[Na+].[OH-],,test
US20160184318A1,C1CCNCC1.Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)N2CCC(O)(Cn3cc(C(=O)O)cn3)CC2)n1>>Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)N2CCC(O)(Cn3cc(C(=O)N4CCCCC4)cn3)CC2)n1,,CN(C)C=O,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US06294532B1,CSc1ncnc2cc(O)ccc12.OCC=CCN1CCOCC1>>CSc1ncnc2cc(OCC=CCN3CCOCC3)ccc12,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100317659A1,NC(=O)c1ccccc1NC(=O)C(F)(F)c1ccc(F)cc1>>Oc1nc(C(F)(F)c2ccc(F)cc2)nc2ccccc12,,ClCCCl,,C[Si](C)(C)Cl,,test
US20050131068A1,CC(=O)NCc1ccc(OC(F)(F)F)cc1>>CCNCc1ccc(OC(F)(F)F)cc1,,C1CCOC1,CCOCC,B,,test
US04902794,CCCCC(=O)OC(=O)CCCC.OCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2>>CCCCC(=O)O.OCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2,,O,,,,test
US20080293776A1,C[Si](C)(C)CCN1C(=O)CN(c2ccc(CO)cc2OCc2ccccc2)S1(=O)=O.II>>C[Si](C)(C)CCN1C(=O)CN(c2ccc(CI)cc2OCc2ccccc2)S1(=O)=O,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06114310,CC(C)(C)OC(=O)N[C@@H](COS(C)(=O)=O)Cc1ccccc1.CCN(C(C)C)C(C)C.CN(C)C=O.ClCCl.Sc1ccc2ccccc2c1>>CC(C)(C)OC(=O)N[C@@H](CS)Cc1ccccc1.c1ccc2cc(Sc3ccc4ccccc4c3)ccc2c1,,CN(C)C=O,ClCCl,[I-].[Na+],,test
US20130059853A1,CCCBr.COc1ccc(-c2cccc3c2CCC3=O)c(O)c1OC(F)F>>CCCOc1c(-c2cccc3c2CCC3=O)ccc(OC)c1OC(F)F,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110152279A1,CN(CCOCCN(C)S(N)(=O)=O)C(=O)COc1ccccc1-c1c(C2CCCCC2)c2ccc(C(=O)O)cc2n1C.O=C(n1ccnc1)n1ccnc1>>CN(CCOCCN(C)S(N)(=O)=O)C(=O)COc1ccccc1-c1c(C2CCCCC2)c2ccc(C(=O)n3ccnc3)cc2n1C,,CC#N,,,,test
US20050014724A1,COc1ccc(CBr)cc1.OCc1ccc(Cl)c(C(F)(F)F)c1>>COc1ccc(COCc2ccc(Cl)c(C(F)(F)F)c2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US06660759B1,CO[C@H]1C[C@H](c2nc(-c3ccccc3)c(-c3ccccc3)o2)N(Cc2cccc(OCC(=O)O)c2)C1.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>CO[C@H]1C[C@H](c2nc(-c3ccccc3)c(-c3ccccc3)o2)N(Cc2cccc(OCC(=O)O)c2)C1.O=C(O)C(O)C(O)C(=O)O,,CCO,,CCCCCC,,test
US20090233928A1,Cl.N#CN.Nc1ccc(N2CCOCC2)nc1>>Cl.N=C(N)Nc1ccc(N2CCOCC2)nc1,,C1COCCO1,,,,test
US20030018046A1,OCC(O)CBr.c1ccc2[nH]cnc2c1>>CC(O)C(O)n1cnc2ccccc21,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090069327A1,CN1CCN(c2cc(C(=O)O)cc(C(F)(F)F)c2)CC1.Cc1ccc(N)cc1Nc1ncccc1-c1cc(NC2CC2)ncn1>>Cc1ccc(NC(=O)c2cc(N3CCN(C)CC3)cc(C(F)(F)F)c2)cc1Nc1ncccc1-c1cc(NC2CC2)ncn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120071467A1,COC(=O)c1ccc(CN)cc1.O=Cc1ccc(O)cc1>>COC(=O)c1ccc(CNCc2ccc(O)cc2)cc1,,CCO,,[BH4-].[Na+],,test
US20080004309A1,CCOC(=O)CN(Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(=O)OCC)C(=O)OC(C)(C)C>>CCOC(=O)c1ncc2nc(-c3ccc(C(F)(F)F)cc3)sc2c1O,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20140088124A1,Fc1ccc(-c2nc3cc(Cl)ccc3[nH]2)cn1.OCC1CCNCC1>>OCC1CCN(c2ccc(-c3nc4cc(Cl)ccc4[nH]3)cn2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20110135671A1,CCCCOc1nc(N)c2nc(OC)n(CCCCN3CCN(C(=O)OC(C)(C)C)CC3)c2n1>>CCCCOc1nc(N)c2[nH]c(=O)n(CCCCN3CCNCC3)c2n1,,CO,CS(C)=O,C1COCCO1,Cl,test
US20150353537A1,CC1CC(=O)CCN1C(=O)OC(C)(C)C.Cl>>CC1CC(=O)CCN1.Cl,,C1COCCO1,CCOC(C)=O,,,test
US05599832,Clc1cc(Cl)cc(-c2cc3cc(Cl)cc(Cl)c3[nH]2)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(c1c(-c2cc(Cl)cc(Cl)c2)[nH]c2c(Cl)cc(Cl)cc12)C(F)(F)F,,CN(C)C=O,,,,test
US20050256201A1,CC(=O)Oc1cccc(CCCCBr)c1.CC1(C)OCc2cc([C@@H]3CN(CCc4ccc(O)cc4)C(=O)O3)ccc2O1>>CC(=O)Oc1cccc(CCCCOc2ccc(CCN3C[C@@H](c4ccc5c(c4)COC(C)(C)O5)OC3=O)cc2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160108030A1,CC(C)(C)OC(=O)CBr.CCOC(=O)c1n[nH]c2c1[C@H]1C[C@H]1C2O>>CCOC(=O)c1c2c(nn1CC(=O)OC(C)(C)C)C(O)[C@@H]1C[C@H]21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030225110A1,COc1c(OC(C)=O)ccc(C=O)c1Br.COc1ccccc1O>>COc1cc(C=O)c(Oc2ccccc2OC)cc1O,O=[Cu],c1ccncc1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140323463A1,C=CC(=O)Cl.CCN(C(C)C)C(C)C.CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(C)[C@H](CO)C3)cc2)nc1Oc1cccc(N)c1.ClC(Cl)Cl.O>>C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(C)[C@H](COC(=O)C=C)C4)cc3)c(C(N)=O)nc2CC)c1,,ClC(Cl)Cl,,ClCCl,,test
US20120283264A1,CC(C(=O)O)c1cncc(Br)c1.O=Cc1cc(F)ccc1F>>CC(C(=O)O)(c1cncc(Br)c1)C(O)c1cc(F)ccc1F,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US06969711B2,COC(=O)c1cccc2nc(S)oc12>>OCc1cccc2nc(S)oc12,,C1CCOC1,Cc1ccccc1,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20060111375A1,BrCC1CO1.COc1cc2c(Oc3cc(C)c(C)nc3-c3nc(C)c(C)s3)ccnc2cc1O>>COc1cc2c(Oc3cc(C)c(C)nc3-c3nc(C)c(C)s3)ccnc2cc1OCC1CO1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05654316,COc1cc(CNC(=O)CC(CCO)c2ccc(Cl)c(Cl)c2)cc(OC)c1.CS(C)=O>>COc1cc(CN(C)C(=O)CC(CC=O)c2ccc(Cl)c(Cl)c2)cc(OC)c1,,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20080176864A1,CC(C)=C[Mg]Br.CON(C)C(=O)c1cccnc1>>CC(C)=CC(=O)c1cccnc1,,C1CCOC1,,O,[Cl-].[NH4+],test
US04371708,CC(=O)C(C)(C)CO.COS(=O)(=O)OC>>COCC(C)(C)C(C)=O,,O,,[Na+].[OH-],,test
US05942536,Nc1ccc([N+](=O)[O-])cc1.O=C(Cl)c1ccc(F)cc1>>O=C(Nc1ccc([N+](=O)[O-])cc1)c1ccc(F)cc1,,ClCCl,,O,c1ccncc1,test
US20060173018A1,CC(C)(C)OC(=O)N1CCC[C@@H](CN)C1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@@H](CNC(=O)OCc2ccccc2)C1,,ClCCl,,CCN(CC)CC,,test
US20090137581A1,Clc1ncnc2nc[nH]c12.NCc1cc2cccc(Cl)c2nc1-c1cc(F)cc(F)c1>>Fc1cc(F)cc(-c2nc3c(Cl)cccc3cc2CNc2ncnc3[nH]cnc23)c1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20160016908A1,CC(=O)N1c2ccc(F)cc2[C@H](NC(=O)OCc2ccccc2)[C@@H](C)[C@@H]1C>>CC(=O)N1c2ccc(F)cc2[C@H](N)[C@@H](C)[C@@H]1C,[Pd],CCO,,,,test
US20020032338A1,C=Cc1cccc(Cl)c1.O=C(OO)c1cccc(Cl)c1>>Clc1cccc([C@@H]2CO2)c1,,ClCCl,,C[N+]1([O-])CCOCC1,,test
US20090105244A1,CC(=O)NCCO.Cc1c(Cl)c(S(C)=O)nc2sc(C(=O)NC3CC3)c(N)c12>>CC(=O)NCCOc1nc2sc(C(=O)NC3CC3)c(N)c2c(C)c1Cl,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20070249670A1,CC(C)(C)OC(=O)[C@H]1CCCN1C(=O)c1cc2ccccc2cc1N.Cc1cc(C)c(N=C=O)c(C)c1>>Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)N2CCC[C@@H]2C(=O)OC(C)(C)C)c(C)c1,,c1ccncc1,,,,test
US20020032208A1,COC(=O)Oc1ccc(F)cc1C.O=[N+]([O-])O>>Cc1cc(F)c([N+](=O)[O-])cc1O,,O=S(=O)(O)O,,,,test
US05578620,BrCC1CO1.OCCCCCCCCc1ccccc1>>c1ccc(CCCCCCCCOCC2CO2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04207228,CC(C)(N)CN.CC(C)=CC(=O)O>>CC1(C)C=NC(=O)CC(C)(C)N1,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20080280924A1,CC(C)(C)NS(=O)(=O)c1cccc(-c2cc(-c3nc(-c4ccc(C(F)(F)F)nc4)cc(C(F)(F)F)n3)ccn2)c1>>NS(=O)(=O)c1cccc(-c2cc(-c3nc(-c4ccc(C(F)(F)F)nc4)cc(C(F)(F)F)n3)ccn2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140011796A1,C=CCC1CC(c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N(C(CC)CN)C1=O.CC(=O)OC(C)=O>>C=CCC1CC(c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N(C(CC)CNC(C)=O)C1=O,,CN(C)C=O,,,,test
US20090143385A1,CC(C)(N)CO.Cc1onc(-c2ccc(F)cn2)c1COc1ccc(C(=O)O)nn1>>Cc1onc(-c2ccc(F)cn2)c1COc1ccc(C(=O)NC(C)(C)CO)nn1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20070088041A1,CCOC(=O)c1cc(-c2ccncc2)n[nH]c1=O.NN>>NNC(=O)c1cc(-c2ccncc2)n[nH]c1=O,,CCO,,O,,test
US04094994,COc1cccc(C(C)O)c1.Cl>>COc1cccc(C(C)Cl)c1,,O,,,,test
US20140171412A1,C[C@@H](N)CO.Cn1c(=O)c2c(-c3ccccc3)n(CCN)cc2n(C)c1=O>>C[C@H](CO)n1cc2c(c1-c1ccccc1)c(=O)n(C)c(=O)n2C,,CCO,,CCN(CC)CC,,test
US20050090493A1,CNC.c1ccc(Nc2ccnc(Nc3ccc(OCC4CO4)cc3)n2)cc1>>CN(C)CC(O)COc1ccc(Nc2nccc(Nc3ccccc3)n2)cc1,,CCO,CN(C)C=O,,,test
US20050143443A1,CCOC(=O)c1cc(C[C@H](C)c2ccccc2)[nH]n1>>C[C@@H](Cc1cc(C(=O)O)n[nH]1)c1ccccc1,,CO,,[Na+].[OH-],,test
US20140057909A1,CC(C)CCn1cc(/C=C/C(=O)O)c2ccccc21.CC(C)NNC(=O)c1ccc(F)cc1>>CC(C)CCn1cc(/C=C/C(=O)N(NC(=O)c2ccc(F)cc2)C(C)C)c2ccccc21,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070155744A1,CCCC[Sn](CCCC)(CCCC)c1cccs1.O=C(NCc1ccc(F)cc1)c1cc(I)nc(OCc2ccccc2)c1O>>O=C(NCc1ccc(F)cc1)c1cc(-c2cccs2)nc(O)c1O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,CN(C)C=O,Cl,,test
US20070129347A1,CN(C)C1(c2ccc(F)cc2)CCC(=CC(=O)NCCCc2ccccc2)CC1>>CN(C)C1(c2ccc(F)cc2)CCC(CC(=O)NCCCc2ccccc2)CC1,[Pd],CO,,Cl,,test
US20090036684A1,CCOC(=O)CC(=O)c1cc(Cc2cccc(Cl)c2F)c(OC)cc1F.COC(OC)N(C)C>>CCOC(=O)C(=CN(C)C)C(=O)c1cc(Cc2cccc(Cl)c2F)c(OC)cc1F,,Cc1ccccc1,,,,test
US20060094712A1,NC(=NO)c1cccc(Oc2ccc3c(c2)S(=O)(=O)N=CN3CCF)c1>>NC(=NO)c1cccc(Oc2ccc3c(c2)S(=O)(=O)NCN3CCF)c1,,CCO,,Cl,[BH4-].[Na+],test
US20160002263A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc3nn2c1N1CCC(C)(CC1)OCC=CCOc1ccccc1Cc1cnc-3s1>>Cc1nc2cc3nn2c(c1[C@H](OC(C)(C)C)C(=O)O)N1CCC(C)(CC1)OCC=CCOc1ccccc1Cc1cnc-3s1,,CO,,[Na+].[OH-],,test
US20130225552A1,CC(C)(C)OC(=O)N[C@@H]1C[C@@H](N2C(=O)C(C)(C)c3cccnc32)C1.Cl>>CC1(C)C(=O)N([C@H]2C[C@H](N)C2)c2ncccc21.Cl,,CCOC(C)=O,,C1COCCO1,,test
US20120028959A1,COC(=O)c1c(F)c(F)c(Br)c(F)c1F.OB(O)c1ccccc1>>COC(=O)c1c(F)c(F)c(-c2ccccc2)c(F)c1F,,O,,Cc1ccccc1,O=C([O-])[O-].[Cs+].[Cs+],test
US20150307445A1,CCOC(=O)CBr.COc1ccc2c(c1)CCCC2=O>>COc1ccc2c(c1)CCC(CC(=O)O)C2=O,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20160009677A1,COC(=O)c1cccc(Br)c1CBr.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>COC(=O)c1cccc(Br)c1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-],,CCCCCC,Cc1ccccc1,,,test
US20110112122A1,BrCc1ccccc1.O=[N+]([O-])c1ccc(Br)cc1O>>O=[N+]([O-])c1ccc(Br)cc1OCc1ccccc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080182852A1,C[C@H](CO)NCC(=O)Nc1cccc([N+](=O)[O-])c1>>C[C@@H]1CN(c2cccc([N+](=O)[O-])c2)C(=O)CN1,,CCOC(C)=O,,CCCCP(CCCC)CCCC,,test
US20080207694A1,COC(=O)CCCC1CCNCC1.O=S(=O)(Cl)c1ccccc1>>COC(=O)CCCC1CCN(S(=O)(=O)c2ccccc2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20110098288A1,CCOC(=O)Cc1ccc(Nc2ncc(Cl)c(Nc3ccccc3NS(C)(=O)=O)n2)cc1>>CS(=O)(=O)Nc1ccccc1Nc1nc(Nc2ccc(CC(=O)O)cc2)ncc1Cl,,CO,O,Cl,[Li+].[OH-],test
US20150344490A1,CCOC(C)(OCC)OCC.COc1ccc(Nc2ccncc2N)c(C)c1>>COc1ccc(-n2c(C)nc3cnccc32)c(C)c1,,CCOC(C)=O,,CC(=O)OC(C)=O,,test
US05466861,C=C(c1ccc(C(=O)OC)cc1)c1cc2c(cc1C)C(C)(C)CCC2(C)C>>C=C(c1ccc(C(=O)O)cc1)c1cc2c(cc1C)C(C)(C)CCC2(C)C,,CO,,Cl,[K+].[OH-],test
US04338450,CCC(=O)NSCl.CN=C=O.F>>CC(=O)N(C)SN(C)C(=O)F,,Cc1ccccc1,O,CCN(CC)CC,,test
US20140288123A1,CC(C)(C)OC(=O)c1ccc(F)cc1.N#Cc1cccc(O)c1>>CC(C)(C)OC(=O)c1ccc(Oc2cccc(C#N)c2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080009512A1,CC(=O)NCC(=O)Nc1ccccc1C(=O)c1ccc(F)cc1>>CC(=O)Nc1c(-c2ccc(F)cc2)c2ccccc2[nH]c1=O,,CCO,,CC(C)(C)[O-].[K+],,test
US20130196998A1,CC(CN1CCC2(CC1)COc1cc(OCc3c(Cl)cccc3C3CC3)ccc12)C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CC(CN1CCC2(CC1)COc1cc(OCc3c(Cl)cccc3C3CC3)ccc12)C(=O)O.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20100029621A1,Nc1c(F)cc(C(=O)N2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1F.O=C(Nc1ccncc1)Oc1ccccc1>>O=C(Nc1ccncc1)Nc1c(F)cc(C(=O)N2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1F,,C1COCCO1,,,,test
US20150037526A1,C=CC(=O)Cl.OCC1CC=CCC1>>C1=CCCCC1.C=CC(=O)OC,,ClCCl,,CCN(CC)CC,,test
US20030032671A1,Cc1ccc(N)c(C)c1.O=C(Br)CBr>>Cc1ccc(NC(=O)CBr)c(C)c1,,ClCCl,,CCN(CC)CC,,test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4c(C#N)cccc4nn23)CC1.Cl>>Cl.N#Cc1cccc2nn3c(C4CCNCC4)cc(=O)[nH]c3c12,,C1COCCO1,,,,test
US20140364433A1,C[C@@H]1CCCN(C(=O)c2cc(F)ccc2-c2ncccn2)[C@@H]1CN.Fc1ccc(C(F)(F)F)cn1>>C[C@@H]1CCCN(C(=O)c2cc(F)ccc2-c2ncccn2)[C@@H]1CNc1ccc(C(F)(F)F)cn1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20110034461A1,CC(=O)Cl.CC(=O)c1ccc(S(F)(F)(F)(F)F)cc1N>>CC(=O)Nc1cc(S(F)(F)(F)(F)F)ccc1C(C)=O,,ClCCl,O,CCN(CC)CC,O=C([O-])O.[Na+],test
US20120283273A1,Clc1cc(Cl)ncn1.NCc1ccc2[nH]c(C(F)(F)F)cc2c1>>FC(F)(F)c1cc2cc(CNc3cc(Cl)ncn3)ccc2[nH]1,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20160016948A1,BrCCOC1CCCCO1.Cc1c[nH]nc1I>>Cc1cn(CCOC2CCCCO2)nc1I,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150158815A1,CC1(C)OB(c2ccc(O)c(Cl)c2)OC1(C)C.NC(=O)C(Nc1cncc(Cl)n1)c1ccccc1>>NC(=O)C(Nc1cncc(-c2ccc(O)c(Cl)c2)n1)c1ccccc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090270443A1,CCOCc1nc2c(Cl)nc(C)c(C)c2n1N.O=C1CCOCC1>>CCOCc1nc2c(Cl)nc(C)c(C)c2n1N=C1CCOCC1,,CC#N,,CC(=O)O,,test
US20110178056A1,C=CS(C)(=O)=O.CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC[C@H]4N)no2)cc1C#N>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC[C@H]4NCCS(C)(=O)=O)no2)cc1C#N,,CC(=O)N(C)C,,Cl,,test
US20150018422A1,CCOC(=O)C=C(c1ccnc(COCOC)c1)C1CC1>>CCOC(=O)CC(c1ccnc(CO)c1)C1CC1,[Zn],CC(=O)O,,,,test
US20080146637A1,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.CCC(=O)c1ccccc1-c1ccc2[nH]c(COc3ccc(C(F)(F)F)cc3)nc2c1>>CC=C(O[Si](C)(C)C(C)(C)C)c1ccccc1-c1ccc2[nH]c(COc3ccc(C(F)(F)F)cc3)nc2c1,,ClCCl,,CCN(CC)CC,,test
US20090111778A1,CC(C)(C)OC(=O)N1CCC(CCCC(=O)c2ncco2)CC1.CC(C)(C)OC(=O)N1CCC(CCCC(O)c2ncco2)CC1>>CC(C)(C)OC(=O)N1CCC(CCCC(=O)c2ncc(C(=O)O)o2)CC1,,CO,,[BH4-].[Na+],,test
US20130150407A1,COC(=O)Cc1cc2ccc(F)cc2c(C2CCN(C(=O)Nc3ccc(Cl)cc3Cl)CC2)c1C>>Cc1c(CC(=O)O)cc2ccc(F)cc2c1C1CCN(C(=O)Nc2ccc(Cl)cc2Cl)CC1,,C1CCOC1,O,[Li+].[OH-],,test
US20100120806A1,Cl.Cn1cc(-c2cc(Oc3cc(F)c(NC(=O)C4(C(=O)Nc5ccccc5)CC4)cc3F)ccn2)cn1>>Cl.Cn1cc(-c2cc(Oc3cc(F)c(NC(=O)C4(C(=O)Nc5ccccc5)CC4)cc3F)ccn2)cn1,,CC#N,,C1COCCO1,,test
US20100075948A1,N#CCc1ccc(Cl)cc1F.O=Cc1cc(F)cc(Cl)c1>>N#C/C(=C\c1cc(F)cc(Cl)c1)c1ccc(Cl)cc1F,,CO,,C[O-].[Na+],,test
US20150232461A1,CC1(C)OC(=O)CC(=O)O1.CCO.O=C(O)Cc1ccccc1F>>CCOC(=O)CC(=O)Cc1ccccc1F,CN(C)c1ccncc1,CCO,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20110263612A1,Nc1ccc(-c2cc3ocnc3cc2Cl)cn1.O=C(Cl)c1ccccc1Cl>>O=C(Nc1ccc(-c2cc3ocnc3cc2Cl)cn1)c1ccccc1Cl,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20060019965A1,CC(C)(C)c1ccc(-c2nc3c(N4CCN(Cc5ccc(N)c(N)c5)CC4)cccc3[nH]2)cc1.O=C(C(=O)n1ccnc1)n1ccnc1>>CC(C)(C)c1ccc(-c2nc3c(N4CCN(Cc5ccc6[nH]c(=O)c(=O)[nH]c6c5)CC4)cccc3[nH]2)cc1,,CCOC(C)=O,,C1CCOC1,,test
US20060138083A1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.O=C(O)CCCCCCCCCCS>>O=C(O)CCCCCCCCCCSC(c1ccccc1)(c1ccccc1)c1ccccc1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US07132443B2,Fc1ccc(C(F)(F)F)cc1.N#CC1CCCC1>>N#CC1(c2ccc(C(F)(F)F)cc2)CCCC1,,Cc1ccccc1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20130252934A1,Cc1cc(Nc2nccc(-c3ccn([C@H](CO[Si](C)(C)C(C)(C)C)c4ccc(Cl)c(F)c4)c(=O)c3)n2)ccn1>>Cc1cc(Nc2nccc(-c3ccn([C@H](CO)c4ccc(Cl)c(F)c4)c(=O)c3)n2)ccn1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100298324A1,Cl.Nc1cc(C(=O)O)ccc1C(=O)O>>O=C(O)c1ccc(C(=O)O)c(Cl)c1,,O,,O=N[O-].[Na+],,test
US04777299,CC(=O)O.CCCc1c(OC)cccc1OC>>CCCc1c(O)ccc(C(C)=O)c1O,,O,,Br,,test
US20080306125A1,O=C(O)CS.O=Cc1c(F)cccc1Br>>O=C(O)c1cc2c(Br)cccc2s1,,CN(C)C=O,,[K+].[OH-],,test
US20040092556A1,CC(C)(C)OC(=O)NCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O>>CC(C)(C)OC(=O)NCCC[C@H](N)C(=O)O,,CN(C)C=O,,CCNCC,,test
US20080171743A1,C[C@H]1COCCN1c1cc(CS(=O)(=O)c2ccccn2)nc(-c2ccc(N)cc2)n1.O=C(Cl)Oc1ccccc1>>C[C@H]1COCCN1c1cc(CS(=O)(=O)c2ccccn2)nc(-c2ccc(NC(=O)Oc3ccccc3)cc2)n1,,C1COCCO1,,O=C([O-])O.[Na+],,test
US20010023249A1,CC(C)CC=O.CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N1CCC(Nc2ccc(OCc3ccccc3)cc2)CC1>>CCC(C)CN(c1ccc(OCc2ccccc2)cc1)C1CCN(C(=O)[C@H](CC(C)C)NC(=O)N2CCCCCC2)CC1,,CCOC(C)=O,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100234351A1,COC(=O)C1=Cc2c(OC)ncnc2N(Cc2ccc(OC)cc2)CC1>>COC(=O)C1=Cc2c(ncnc2OC)NCC1,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US06703421B1,CC(C)(C)OC(=O)NC1Cc2ccc(C(=O)O)cc2C1.NCc1ccccc1>>CC(C)(C)OC(=O)NC1Cc2ccc(C(=O)NCc3ccccc3)cc2C1,,ClCCl,,CCN(CC)CC,CN(C)c1ccccn1,test
US20140107340A1,CC(C)(C)OC(=O)NCC(c1ccccc1)c1ccnnc1>>NCC(c1ccccc1)c1ccnnc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20150274767A1,CS[Na].Clc1ncnn2cccc12>>CSc1ncnn2cccc12,,C1CCOC1,,,,test
US05643932,COc1cc(C(N)=O)cc(OC)c1OC.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>COc1cc(C(N)=S)cc(OC)c1OC,,c1ccccc1,,,,test
US20130150343A1,CC(C)[Si](OCCN(C)c1nnc2ccc(F)cn12)(C(C)C)C(C)C.N[C@H]1CC[C@@H](O)c2ccccc21>>CC(C)[Si](OCCN(C)c1nnc2ccc(O[C@@H]3CC[C@H](N)c4ccccc43)cn12)(C(C)C)C(C)C,,CN(C)C=O,O,[H-].[Na+],[Cl-].[NH4+],test
US20160206616A1,CC(CC(=O)O)[C@@H]1CC(F)(F)CN1C(=O)OC(C)(C)C.Cl>>CC(CC(=O)O)[C@@H]1CC(F)(F)CN1.Cl,,CCOC(C)=O,,,,test
US20130210844A1,CC(C)C(=O)Cl.CCOC(=O)c1c(Cl)ccc(CN)c1F>>CCOC(=O)c1c(Cl)ccc(CNC(=O)C(C)C)c1F,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20130085128A1,CC[C@@H](NCc1ccc(OC)cc1)C(=O)OC.C[C@H](NC(=O)OC(C)(C)C)C(=O)O>>CC[C@@H]1CN[C@@H](C)CN1Cc1ccc(OC)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120225857A1,CCN(C)S(=O)(=O)c1ccc([Sn](C)(C)C)nc1.Nc1ncc(Br)cc1-c1ccc2c(c1)CCNC2=O>>CCN(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3ccc4c(c3)CCNC4=O)c2)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US06140100,BrP(Br)(c1ccccc1)(c1ccccc1)c1ccccc1.CC(C)(C)c1cc(CO)ccc1O[Si](C)(C)C(C)(C)C>>CC(C)(C)c1cc(CBr)ccc1O[Si](C)(C)C(C)(C)C,,ClCCl,,,,test
US05721234,O=C(O)C1Cc2ccc3[nH]c(=O)c(=O)[nH]c3c2C1.O=[N+]([O-])O>>O=C(O)C1Cc2c([N+](=O)[O-])cc3[nH]c(=O)c(=O)[nH]c3c2C1,,O=C(O)C(F)(F)F,,,,test
US20040209921A1,CC1=CC(C(F)(F)F)=CNC1(C)CO>>Cc1cc(C(F)(F)F)cnc1C=O,O=[Mn]=O,ClCCl,,,,test
US20110288090A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4ccnc(O)c4cc3-c3ccccc3)cc2)CCC1.O=C1CCC(=O)N1I>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(I)cnc(O)c4cc3-c3ccccc3)cc2)CCC1,,CC#N,,,,test
US20150240084A1,C=COCCCCO.CC(C)N=C=NC(C)C.CCCCCCCCCCCCCCCCCCN.CN(C)c1ccccn1.ClCCl.O=C1C=CC(=O)O1>>CCCCCCCCCCCCCCCCCCOC(=O)/C=C\C(=O)OCCCCCCCCCCCCCCCCCC,,ClCCl,,,,test
US20120010189A1,CC(=O)N1CCN(Cc2ccc(O)cc2)CC1.CC(C)(C)OC(=O)N1CC(OS(C)(=O)=O)C1>>CC(=O)N1CCN(Cc2ccc(OC3CN(C(=O)OC(C)(C)C)C3)cc2)CC1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20050009808A1,CCOC(=O)[C@@H]1NC2CCC1CC2.COc1ccc(S(=O)(=O)Cl)cc1>>CCOC(=O)[C@H]1C2CCC(CC2)N1S(=O)(=O)c1ccc(OC)cc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20150322043A1,CC(=O)Nc1cccc(-c2ccc(Cl)c(C(=O)Nc3cc(C#N)nn3-c3ccccc3)c2)n1.OO>>CC(=O)Nc1cccc(-c2ccc(Cl)c(C(=O)Nc3cc(C(N)=O)nn3-c3ccccc3)c2)n1,,CS(C)=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20120108582A1,C[C@H](c1ccccc1)N1C[C@]2(C(=O)OC(C)(C)C)CC[C@H](F)[C@H]2C1=O.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)[C@@]12CC[C@H](F)[C@@H]1CN(C(=O)OCc1ccccc1)C2,,C1CCOC1,CCN(CC)CC,CCO,O,test
US20120302752A1,CCN(CC)C(=O)c1ccc2ccccc2c1OC.Cc1ccc(B2OCC(C)(C)CO2)cc1>>CCN(CC)C(=O)c1ccc2ccccc2c1-c1ccc(C)cc1,,Cc1ccccc1,,,,test
US20080021032A1,CCCCCCn1ccc([N+](=O)[O-])n1>>CCCCCCn1ccc(N)n1,[Pd],CCOC(C)=O,,CO,[H][H],test
US04166188,CCC#CCC1(C(=O)OC(C)(C)C)C(=O)C=CC1CC(=O)OC>>CCC#CCC1C(=O)C=CC1CC(=O)OC,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US03940393,CC(=O)c1nc(N)nc(N)c1-c1ccc(Cl)cc1>>CC(=O)c1nc(N)nc(N)c1-c1ccc(Cl)cc1,,O,,Cl,,test
US20070123527A1,COC(=O)Cl.NCCC(c1ccccc1)c1cccc2[nH]ccc12>>COC(=O)NCCC(c1ccccc1)c1cccc2[nH]ccc12,,ClCCl,,,,test
US20150175540A1,CC(Oc1cccc(O)c1)[C@@H]1CC[C@@H](CN2Cc3ccc(OCc4ccccc4)c(F)c3C2=O)CC1.CN(C)CCCl>>CC(Oc1cccc(OCCN(C)C)c1)[C@@H]1CC[C@@H](CN2Cc3ccc(OCc4ccccc4)c(F)c3C2=O)CC1,,C1COCCO1,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US04337341,O=C(Cl)Cc1ccccc1.c1ccc(C23CCCC2CNCC3)cc1>>O=C(Cc1ccccc1)C1NCCC2(c3ccccc3)CCCC12,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20060040999A1,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.OCc1cscn1>>CC(C)(C)[Si](C)(C)OCc1cscn1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US05472933,COC(=O)c1ccn(C)c1S(N)(=O)=O.COc1nc(C)nc(NC(=O)Oc2ccccc2)n1>>COC(=O)c1ccn(C)c1S(=O)(=O)NC(=O)Nc1nc(C)nc(OC)n1,,CC#N,O,C1CCC2=NCCCN2CC1,Cl,test
US05827881,CCCCNCCCC.CCOC(=O)CC(C)=O>>CCCCN(CCCC)C(=O)CC(C)=O,,CCOCC,,,,test
US06100254,C=CCOC(=O)COc1ccc(COc2cccc(C(=O)c3ccccc3)c2N)cc1.O=C(Cl)OCc1cccc2c1Cc1ccccc1-2>>C=CCOC(=O)COc1ccc(COc2cccc(C(=O)c3ccccc3)c2NC(=O)OCc2cccc3c2Cc2ccccc2-3)cc1,,ClCCl,,c1ccncc1,,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4cccc(-c5nn[nH]n5)c4)nc(Cl)c3n2)cc1.COc1ccc(N)cc1OC>>COc1ccc(Nc2nc(-c3cccc(-c4nn[nH]n4)c3)nc3cn[nH]c23)cc1OC,C1COCCO1,CO,,Cl,,test
US20080015146A1,CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCC[C@H]1c1noc(C2(F)CC2)n1)Cc1cc(F)c(F)cc1F>>N[C@@H](CC(=O)N1CCC[C@H]1c1noc(C2(F)CC2)n1)Cc1cc(F)c(F)cc1F.O=CO,,ClCCl,O=C(O)C(F)(F)F,,,test
US20160068489A1,Cc1nc(N)c(C)c(C)c1OCc1ccccc1.O=C(Cl)c1ccccc1>>Cc1nc(NC(=O)c2ccccc2)c(C)c(C)c1OCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20120088767A1,COC(=O)c1cc(N2CCOCC2)cc2nc(C)[nH]c12.Cc1ccc(CCl)cc1C>>COC(=O)c1cc(N2CCOCC2)cc2c1nc(C)n2Cc1ccc(C)c(C)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100121048A1,CCOC(=O)COc1ccc(C[C@@H]2CN(Cc3ccccc3)CCN2C(=O)c2cc(C)n(-c3ccccc3)c2-c2ccccc2)cc1>>Cc1cc(C(=O)N2CCN(Cc3ccccc3)C[C@H]2Cc2ccc(OCC(=O)O)cc2)c(-c2ccccc2)n1-c1ccccc1,,CCO,,[Na+].[OH-],,test
US06166006,Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CCl)cc2)CC3)cc1.OCCNCCO>>Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CN(CCO)CCO)cc2)CC3)cc1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20140113882A1,CN.Cc1ccc(S(=O)(=O)OC[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)cc1>>CNC[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C,,C1CCOC1,CCOC(C)=O,,,test
US03956495,C1COCCN1.CCN(CC)CCNc1nc(Cl)nc2ccccc12>>CCN(CC)CCNc1nc(N2CCOCC2)nc2ccccc12.Cl,,C1CCOC1,,,,test
US20060014701A1,CCOC(=O)[C@@H]1CCCN1C(=O)C(CC)CC>>CCC(CC)C(=O)N1CCC[C@H]1C(=O)O,,CO,,Cl,[Na+].[OH-],test
US20130116229A1,CCn1cc(C(=O)OC)c2cc(OCCCc3ccc4ccccc4n3)c(OC)cc2c1=O>>CCn1cc(C(=O)O)c2cc(OCCCc3ccc4ccccc4n3)c(OC)cc2c1=O,,CO,O,Cl,[Na+].[OH-],test
US20100087418A1,CCc1cccc2c1OCCN(C(=O)OC(C)(C)C)C2.Cl>>CCc1cccc2c1OCCNC2.Cl,,CCOC(C)=O,,,,test
US20130345123A1,C=CCCN(Cc1ccccc1)C(=O)[C@H](CC=C)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@H]1CC=CCCN(Cc2ccccc2)C1=O,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,ClCCCl,,,,test
US20120295885A1,CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C#N)c5ccc(-c6ccccc6Cl)nc54)c3CO)ncc2c1.O>>CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)c5ccc(-c6ccccc6Cl)nc54)c3CO)ncc2c1,,O,,CCO,,test
US20130338081A1,COC(=O)CSC(C)(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1Cc2cc([C@H]3C[C@@H](C(=O)N[C@@H]4CCCc5ccccc54)N(C(=O)[C@@H](N)C(C)(C)C)C3)ccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21>>COC(=O)CSC(C)(C)[C@H](N)C(=O)N1Cc2cc([C@H]3C[C@@H](C(=O)N[C@@H]4CCCc5ccccc54)N(C(=O)[C@@H](N)C(C)(C)C)C3)ccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080306045A1,CC(C)(C)OC(=O)CN([C@H]1CCN(c2ccc3c(c2)CCCN(C(=O)OC(C)(C)C)C3)C1=O)S(=O)(=O)/C=C/c1ccc(Cl)s1.Cl>>Cl.O=C(O)CN([C@H]1CCN(c2ccc3c(c2)CCCNC3)C1=O)S(=O)(=O)/C=C/c1ccc(Cl)s1,,CCOCC,Cl,,,test
US20060235030A1,Cc1c(F)cc(C(=O)O)cc1-c1nc(NCCN(C)C)nc2c1CNC(=O)N2c1c(F)cccc1F.Nc1ccccc1>>Cc1c(F)cc(C(=O)Nc2ccccc2)cc1-c1nc(NCCN(C)C)nc2c1CNC(=O)N2c1c(F)cccc1F,,ClCCl,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20090270369A1,BrCC1CO1.O=c1[nH]nc2ccccn12>>O=c1n(CC2CO2)nc2ccccn12,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20110118251A1,CS(=O)(=O)OCc1cccnc1Br.c1c[nH]cn1>>Brc1ncccc1Cn1ccnc1,,CCO,,O,O=C([O-])[O-].[K+].[K+],test
US20070275968A1,Cc1cccc(-c2nn(S(=O)(=O)N(C)C)cc2-c2ccc(F)c(-c3ccn(C(=O)OC(C)(C)C)c3)c2)n1>>Cc1cccc(-c2n[nH]cc2-c2ccc(F)c(-c3cc[nH]c3)c2)n1,,CO,,C[O-].[Na+],,test
US20140205537A1,CCOC(=O)CC(=O)OCC.O=[N+]([O-])c1ccc(F)cc1F>>CCOC(=O)C(C(=O)OCC)c1cc(F)ccc1[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20140057893A1,CS(=O)(=O)c1ccc(OCC[C@@H]2C[C@@H]2C2CCNCC2)c(F)c1.N#CBr>>CS(=O)(=O)c1ccc(OCC[C@@H]2C[C@@H]2C2CCN(C#N)CC2)c(F)c1,,ClC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US20070135631A1,COc1cc(C=O)ccc1F.Fc1cc(Br)cc(OC(F)(F)C(F)F)c1>>COc1cc(C(O)c2cc(F)cc(OC(F)(F)C(F)F)c2)ccc1F,,CCOCC,,[Li]CCCC,,test
US20150065522A1,CC(=O)C(C(=O)[O-])C(C)C.Nc1ccn[nH]1>>Cc1[nH]c2ccnn2c(=O)c1C(C)C,,CC(=O)O,,,,test
US04746673,CC(C)(C)C=O.Cl[Mg]Cc1ccc(Cl)cc1>>CC(C)(C)C(O)Cc1ccc(Cl)cc1,,CCOCC,,Cl,,test
US20120214767A1,C=C[Sn](CCCC)(CCCC)CCCC.CCCc1ccc(-c2onc3c2CCc2cc(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)ccc2-3)cc1>>C=Cc1ccc2c(c1)CCc1c-2noc1-c1ccc(CCC)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,[Cl-].[Li+],,test
US20050228004A1,Fc1ccc(-c2cn3cccc(Cl)c3n2)cc1.O=C1CCC(=O)N1I>>Fc1ccc(-c2nc3c(Cl)cccn3c2I)cc1,,ClCCl,,,,test
US20020040138A1,C#CC1CC1.CC(C)(C)[Si](C)(C)Cl>>CC(C)(C)[Si](C)(C)C#CC1CC1,,C1CCOC1,Cc1ccccc1,[Li]CCCC,,test
US20160251339A1,COc1ccc(S(=O)(=O)Cl)cc1N1CCN(C(=O)C(Cl)(Cl)Cl)CC1.Fc1ccc2[nH]ccc2c1>>COc1ccc(S(=O)(=O)n2ccc3cc(F)ccc32)cc1N1CCN(C(=O)C(Cl)(Cl)Cl)CC1,,C1CCOC1,,[H-].[Na+],,test
US20120208815A1,O=C([O-])c1ccccn1>>O=C(O)c1ccccn1,,C1CCOC1,,Cl,[Li+].[OH-],test
US04101661,O=C(O)c1ccc(-c2ccc(S(=O)(=O)N(CCO)CCO)cc2)[nH]c1=O.O=C1CCC(=O)N1O>>O=C(ON1C(=O)CCC1=O)c1ccc(-c2ccc(S(=O)(=O)N(CCO)CCO)cc2)[nH]c1=O,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20040063680A1,CC(C)S(=O)(=O)On1nnc2ccccc21.COc1ccc(C(C)(O)CN)c(F)c1>>COc1ccc(C(C)(O)CNS(=O)(=O)C(C)C)c(F)c1,,CCOC(C)=O,CN(C)C=O,Cl,,test
US20050004113A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1ccc(CN2CC3CNCC(C3)C2)cc1>>CC(C)(C)OC(=O)N1CC2CC(CN(Cc3ccccc3)C2)C1,,C1CCOC1,,,,test
US20090270351A1,COC(=O)c1ccc(/C=N/Cc2ccccc2)cc1.COP([O-])OC>>COC(=O)c1ccc(C(NCc2ccccc2)P(=O)(OC)OC)cc1,,CCOC(C)=O,,,,test
US05196610,ClC(Cl)(Br)C(Cl)(Cl)Br.OCc1cccc(Cc2ccccc2)c1>>BrCc1cccc(Cc2ccccc2)c1,,CCOCC,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20120142671A1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1ccc(C#N)c(Nc2cc(-c3ccccc3)no2)c1.OO>>CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1ccc(C(N)=O)c(Nc2cc(-c3ccccc3)no2)c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20060205946A1,NCc1ccc(O)cc1.O=C(Nc1ccccc1-c1ccccc1)OC1CCNCC1.O=C1CN(CCCCl)C(=O)CN1CCCCl>>O=C(Nc1ccccc1-c1ccccc1)OC1CCN(CCCN2CC(=O)N(CCCNCc3ccc(O)cc3)CC2=O)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20140179670A1,CC(=O)OC[C@@H](C)n1c(=O)c(-c2ccnn2-c2ccc(C#N)cc2)c(C)n(-c2cccc(C(F)(F)F)c2)c1=O>>Cc1c(-c2ccnn2-c2ccc(C#N)cc2)c(=O)n([C@H](C)CO)c(=O)n1-c1cccc(C(F)(F)F)c1,,CCO,,CCOC(C)=O,[Na+].[OH-],test
US20070049593A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(N)=S.CCOC(CBr)OCC>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)c1nccs1,,CC(C)=O,,,,test
US20120070374A1,COc1ccc(N)c(S)c1.O=Cc1ccc(-c2ccc(Cl)nn2)cc1>>COc1ccc2nc(-c3ccc(-c4ccc(Cl)nn4)cc3)sc2c1,,CS(C)=O,,,,test
US20130310379A1,CC1(C)CC(N)CC(C)(C)N1.O=C(O)c1ccc(Nc2ccccc2)nc1>>CC1(C)CC(NC(=O)c2ccc(Nc3ccccc3)nc2)CC(C)(C)N1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120035168A1,COC(=O)c1cn(Cc2ccc(Cn3cccn3)cc2)cn1>>O=C(O)c1cn(Cc2ccc(Cn3cccn3)cc2)cn1,,CO,O,,,test
US20120277220A1,COc1cc(C2CCN(C)CC2)ccc1Nc1ncc2c(=O)c(C(N)=O)c(N)n(-c3ccccc3)c2n1.Cl>>COc1cc(C2CCN(C)CC2)ccc1Nc1ncc2c(=O)c(C(N)=O)c(N)n(-c3ccccc3)c2n1.Cl,,CCOCC,ClCCl,,,test
US20090186891A1,COc1ccc(C(=O)NNC(=O)c2ccc(N)c([N+](=O)[O-])c2)cc1>>COc1ccc(-c2nnc(-c3ccc(N)c([N+](=O)[O-])c3)o2)cc1,,C1CCOC1,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US20050014788A1,CS(=O)(=O)c1ccc(C=CC(=O)O)cc1.C[C@@H]1[C@H](c2ccccc2)NC(=O)N1C>>C[C@@H]1[C@H](c2ccccc2)N(C(=O)/C=C/c2ccc(S(C)(=O)=O)cc2)C(=O)N1C,,ClCCl,,CCN(C(C)C)C(C)C,O=S(Cl)Cl,test
US20060205804A1,C=CC(=O)Cl.C=CCC(O)CCn1c(-c2ccc(F)cc2)c(-c2ccccc2)c(C(=O)Nc2ccccc2)c1C(C)C>>C=CCC(CCn1c(-c2ccc(F)cc2)c(-c2ccccc2)c(C(=O)Nc2ccccc2)c1C(C)C)OC(=O)C=C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20070225280A1,CC(C)(C)n1ncc(C(=O)NC2C3CC4CC(C3)CC2C4)c1Cl.c1cn[nH]c1>>CC(C)(C)n1ncc(C(=O)NC2C3CC4CC(C3)CC2C4)c1-n1cccn1,,CS(C)=O,,[F-].[K+],,test
US20090239866A1,CC(C)(C)[Si](C)(C)Cl.CC1CCNC1=O>>CC1CCN([Si](C)(C)C(C)(C)C)C1=O,,ClCCl,O,CCN(CC)CC,CN(C)c1ccccn1,test
US04517195,CCOC(=O)Cl.Nn1cccc1C(=O)c1ccccc1Cl>>CCOC(=O)Nn1cccc1C(=O)c1ccccc1Cl,,ClCCl,,O=C([O-])O.[Na+],,test
US20100044637A1,CN(C)c1ccnc(I)c1.COc1cccc(B(O)O)c1>>COc1cccc(-c2cc(N(C)C)ccn2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[K+].[K+],,test
US20090005388A1,CN1C2CCCC1CN(c1cccnc1)C2.O=C1CCC(=O)N1Br>>CN1C2CCCC1CN(c1ccc(Br)nc1)C2,,CC#N,,,,test
US20080221180A1,CC(=O)Nc1nc(C)c(-c2cc(S(=O)(=O)N3CCOCC3)sc2Br)s1>>CC(=O)Nc1nc(C)c(-c2csc(S(=O)(=O)N3CCOCC3)c2)s1,,C1CCOC1,,O,[Li]CCCC,test
US20070123505A1,CC(C)(F)C(c1cc(F)cc(C#N)c1)C1CN(C(c2ccccc2)c2ccccc2)C1.[N-]=[N+]=[N-]>>CC(C)(F)C(c1cc(F)cc(-c2nnn[nH]2)c1)C1CN(C(c2ccccc2)c2ccccc2)C1,,CN(C)C=O,,[Cl-].[NH4+],,test
US20150232483A1,C=CCN(CC(=NO)c1cnccn1)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC2CONC2(c2cnccn2)C1,,Cc1ccccc1,,,,test
US20040192701A1,CCN=C=NCCCN(C)C.CCOC(C)=O.CN(C)C=O.CN(C)CCOc1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)cc1.COc1ccc(-c2cccc(C(=O)O)n2)cc1OC.O.On1nnc2ccccc21>>COc1ccc(-c2cccc(C(=O)N3CCN(c4ccc(OCCN(C)C)cc4)CC3)n2)cc1OC.O=C(O)C(=O)O.O=C(O)C(=O)O,,CCN(CC)CC,CN(C)C=O,Cl,Cl,test
US20150182537A1,O=C1OCCC1Br.Oc1ccccc1>>O=C1OCCC1Oc1ccccc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20060100218A1,COc1ccc(B(O)O)cc1OC.O=S(=O)(c1ccccc1)n1cc(Br)c2ccccc21>>COc1ccc(-c2cn(S(=O)(=O)c3ccccc3)c3ccccc23)cc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20110306607A1,O=Cc1ccc2n1-c1ccc(Cl)cc1OC21CCN(C(=O)C(F)(F)F)CC1>>O=Cc1ccc2n1-c1ccc(Cl)cc1OC21CCNCC1,,CO,,O,O=C([O-])[O-].[K+].[K+],test
US20040192733A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(C(F)(F)F)cc2)CC1>>FC(F)(F)c1ccc(OC2CCNCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140243283A1,CC(C)(C)C(=O)OC[C@H]1O[C@H](c2csc([C@H]3O[C@H](COC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@H](OC(=O)C(C)(C)C)[C@@H]3OC(=O)C(C)(C)C)c2)[C@@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C>>OC[C@H]1O[C@H](c2csc([C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)c2)[C@@H](O)[C@@H](O)[C@@H]1O,,CO,,CO[Na],,test
US20150175617A1,O=C1NN=C2CN(C(=O)OCc3ccccc3)Cc3[nH]c4cccc1c4c32>>O=C1NN=C2CNCc3[nH]c4cccc1c4c32,[Pd],CO,,[H][H],,test
US20100048568A1,CC(=O)c1c[nH]c2ncccc12>>CCc1c[nH]c2ncccc12,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20160221946A1,O=Cc1c[nH]c2cc(Br)ccc12.O=S(=O)(Cl)c1cccnc1>>O=Cc1cn(S(=O)(=O)c2cccnc2)c2cc(Br)ccc12,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20110105535A1,CC(=O)C(Br)c1ccnc(Cl)c1.NC(N)=S>>Cc1nc(N)sc1-c1ccnc(Cl)c1,,CCO,,,,test
US20040242584A1,O=C(N[C@@H]1c2cc([N+](=O)[O-])ccc2C[C@H]1O)c1ccc(-c2ccccc2)cc1>>Nc1ccc2c(c1)[C@@H](NC(=O)c1ccc(-c3ccccc3)cc1)[C@H](O)C2,[Pd],CN(C)C=O,,[H][H],,test
US20160068559A1,CC(C)[C@H](CCN(C)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21)NC(=O)Nc1ccc(C(C)(C)C)cc1>>CC(C)[C@H](CCN(C)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)NC(=O)Nc1ccc(C(C)(C)C)cc1,,CO,Cl,,,test
US20070093526A1,COc1nc(Cl)c(C2OCCO2)s1>>COc1nc(Cl)c(C=O)s1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20060069083A1,Cc1ccc(NC(=O)c2cc(Cl)ccc2Cl)c(O)c1>>Cc1ccc2c(c1)Oc1ccc(Cl)cc1C(=O)N2,,CC(=O)N(C)C,,[H-].[Na+],,test
US05990151,COC(=O)C(=Cc1ccc(OC)c(OCCc2ccccc2)c1)C(=O)OC>>COC(=O)C(Cc1ccc(OC)c(OCCc2ccccc2)c1)C(=O)OC,[Pd],CCOC(C)=O,,,,test
US20050222118A1,CCOCC.Clc1ccc([Mg]Br)cc1.N#CC1CN(C(c2ccccc2)c2ccccc2)C1>>O=C(c1ccc(Cl)cc1)C1CN(C(c2ccccc2)c2ccccc2)C1,,Clc1ccccc1,,,,test
US20130217664A1,CCN=C=O.CCc1cc(C2=CCNCC2)ccc1N(C)c1cc2c(cn1)ncn2C>>CCNC(=O)N1CC=C(c2ccc(N(C)c3cc4c(cn3)ncn4C)c(CC)c2)CC1,,ClCCl,,CCN(CC)CC,,test
US20100267775A1,CC(C)(C)OC(=O)NCCCBr.Cc1cc(O)cc(C)c1-c1cccc(COc2ccc(C=O)cc2)c1C>>Cc1cc(OCCCNC(=O)OC(C)(C)C)cc(C)c1-c1cccc(COc2ccc(C=O)cc2)c1C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06127368,CCc1c(C(=O)OC(C)C)ncc2[nH]c3ccc(NC(C)=O)cc3c12.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCc1c(C(=O)OC(C)C)ncc2[nH]c3ccc(NC(C)=S)cc3c12,,C1COCCO1,,CCOC(C)=O,,test
US05502065,CC(C)[Si](C(C)C)(C(C)C)n1cc(C[C@H]2CCCN2C)c2cc(Br)ccc21.CCCC[Sn](Cl)(CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)c1ccc2c(c1)c(C[C@H]1CCCN1C)cn2[Si](C(C)C)(C(C)C)C(C)C,,C1CCOC1,,O,[Li]CCCC,test
US20030199440A1,CC(C)(C)OC(=O)CNS(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1.ClCc1cccc(Cl)c1>>CC(C)(C)OC(=O)CN(Cc1cccc(Cl)c1)S(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04973721,CO[C@H](CCC(C)(C)O)[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(C)=O)C[C@H](OC(C)=O)[C@]4(C)[C@H]3CC[C@]12C>>CO[C@H](CCC(C)(C)O)[C@@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](OC(C)=O)C[C@H](OC(C)=O)[C@]4(C)[C@H]3CC[C@@]21C,,ClC(Cl)(Cl)Cl,,O=C1CCC(=O)N1Br,,test
US07015218B1,N#Cc1cc([N+](=O)[O-])ccc1Cl.Oc1ccccc1>>N#Cc1cc([N+](=O)[O-])ccc1Oc1ccccc1,,O,,CN(C)C=O,[H-].[Na+],test
US20090069288A1,C[Si](C)(C)C#Cc1ccc(C2OCCO2)cc1>>C#Cc1ccc(C2OCCO2)cc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20040072818A1,CNCc1ccccc1.Nc1cc(N2CCN(C(=O)NCC(=O)O)CC2)c2ccc(Cl)cc2n1>>CN(Cc1ccccc1)C(=O)CNC(=O)N1CCN(c2cc(N)nc3cc(Cl)ccc23)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070232679A1,Ic1ccccc1.O=C(O)[C@@H]1CCCN1>>O=C(O)[C@@H]1CCCN1c1ccccc1,[Cu]I,CC(=O)N(C)C,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20050143394A1,O=C(O)Cc1cccc(Cl)c1.O=C1CCCCC1>>O=C(O)C(c1cccc(Cl)c1)C1(O)CCCCC1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20110245221A1,CCOC(=O)c1cc(-c2cc(Cl)c(OCc3ccccc3)cc2OCc2ccccc2)on1>>O=C(O)c1cc(-c2cc(Cl)c(OCc3ccccc3)cc2OCc2ccccc2)on1,,O,,CO,[Li+].[OH-],test
US20150148327A1,CCOC(=O)C(F)(F)C(O)c1ccc(-c2cc(C)cc(Nc3nccc(C(F)(F)F)n3)c2)cn1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(C(O)C(F)(F)C(=O)O)nc2)c1,,C1CCOC1,,CO,[Na+].[OH-],test
US20020019416A1,CC(C)(C)OC(=O)CCc1ccccc1C(=O)N[C@@H](CCCC(=O)OCc1ccccc1)C(=O)O[C@H](CC(N)=O)Cc1ccc2ccccc2c1>>NC(=O)C[C@H](Cc1ccc2ccccc2c1)OC(=O)[C@H](CCCC(=O)OCc1ccccc1)NC(=O)c1ccccc1CCC(=O)O,,CCOC(C)=O,Cl,,,test
US04963566,COc1ccc2nc(S(=O)Cl)[nH]c2c1.[Li]Cc1cccc2c1N(C)CCC2>>COc1ccc2nc(S(=O)Cc3cccc4c3N(C)CCC4)[nH]c2c1,,c1ccccc1,,,,test
US20110166139A1,CON.O=c1[nH]c2cc(F)ccc2c(=O)o1>>CONC(=O)c1ccc(F)cc1N,,CCOC(C)=O,,Cl,[Na+].[OH-],test
US20150011574A1,COC(=O)c1cnc(Cl)cc1OC.COc1ccc(CN)c(OC)c1>>COC(=O)c1cnc(NCc2ccc(OC)cc2OC)cc1OC,,CC(=O)N(C)C,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20080242665A1,CC1(C)OB(c2cccnc2)OC1(C)C.CNC1CCN(C)CC1.O=Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1>>CN1CCC(N(C)Cc2cc3nc(-c4cccnc4)nc(N4CCOCC4)c3s2)CC1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140094459A1,N#CCC(=O)O.Nc1ncnc2c1c(-c1ccc(Oc3cccc(F)c3)cc1)nn2C[C@H]1CCCN1>>N#CCC(=O)N1CCC[C@@H]1Cn1nc(-c2ccc(Oc3cccc(F)c3)cc2)c2c(N)ncnc21,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05041462,CC(=O)OCC(=O)Nc1cccc(N2CCOCC2)c1C#N>>N#Cc1c(NC(=O)CO)cccc1N1CCOCC1,,CO,,N,,test
US04925482,O=C(CC1(Cl)CC1)CC1(Cl)CC1.O=Cc1ccc(Cl)cc1>>O=C(C=Cc1ccc(Cl)cc1)C1(Cl)CC1,,CCO,,O,[Na+].[OH-],test
US06765004B1,O=C(Nc1ccc(C(=O)N2CCCc3c[nH]c4cccc2c34)cc1)c1ccccc1-c1ccccc1.O=S(=O)(O)Cl>>O=C(Nc1ccc(C(=O)N2CCCc3c(S(=O)(=O)O)[nH]c4cccc2c34)cc1)c1ccccc1-c1ccccc1,,ClCCl,,,,test
US20050070441A1,Cc1cc(Oc2ccc(C(F)(F)F)cc2[N+](=O)[O-])nn1C(=O)NC(C)C.O=S(=O)(Cl)Cl>>Cc1c(Cl)c(Oc2ccc(C(F)(F)F)cc2[N+](=O)[O-])nn1C(=O)NC(C)C,,CC(=O)O,,,,test
US20130172278A1,CC(C)[Si](OCc1cc(C2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)sc1Cl)(C(C)C)C(C)C>>OCc1cc(C2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)sc1Cl,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140045862A1,COc1ccc(CN(c2ccncn2)S(=O)(=O)c2ccc(O[C@H]3CCCC[C@@H]3c3ccnn3C)c(F)c2F)c(OC)c1>>Cn1nccc1[C@H]1CCCC[C@@H]1Oc1ccc(S(=O)(=O)Nc2ccncn2)c(F)c1F,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20160000760A1,CNC(=O)c1ccc(B(O)O)cc1F.Nc1nc(Nc2cc(Cl)c(Br)c(C(F)(F)F)c2)n[nH]1>>CNC(=O)c1ccc(-c2c(Cl)cc(Nc3n[nH]c(N)n3)cc2C(F)(F)F)cc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O,O=C([O-])[O-].[Na+].[Na+],test
US03993646,COC(=O)C1N2C(=O)C(NC(=O)COc3ccccc3)[C@H]2SCC1(C)Br>>COC(=O)C1=C(C)CS[C@@H]2C(NC(=O)COc3ccccc3)C(=O)N12,,CC#N,,CC(=O)[O-].[Na+],,test
US20130172556A1,CCC=O.CCc1cc(C)cc(CC)c1C(=O)C(=O)N(C)N>>CCC=NN(C)C(=O)C(=O)c1c(CC)cc(C)cc1CC,,O,,CO,,test
US20110245205A1,CC(C)(C)O.Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C3(O)CCNCC3)s2)c1.O=C=NS(=O)(=O)Cl>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C3(O)CCN(S(=O)(=O)NC(=O)OC(C)(C)C)CC3)s2)c1,,ClCCl,,CCN(CC)CC,,test
US20140296200A1,CCOC(=O)C(=CN(C)C)n1cc(C#N)cn1.NNc1ccc(C(=O)NCC2CCOCC2)cn1>>N#Cc1cnn(-c2cnn(-c3ccc(C(=O)NCC4CCOCC4)cn3)c2O)c1,,CC(C)O,,CCN(C(C)C)C(C)C,Cl,test
US20090264445A1,CCOc1cccc(OC2=CC(=O)N([C@@H](CC(C)C)C(=O)Nc3cnc([C@H]4COC(C)(C)O4)cn3)C2)c1F>>CCOc1cccc(OC2=CC(=O)N([C@@H](CC(C)C)C(=O)Nc3cnc([C@H](O)CO)cn3)C2)c1F,,C1CCOC1,CCOC(C)=O,Cl,,test
US20100168418A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(N1CCC(NCCSc2cccs2)CC1)C(F)(F)F>>CC(C)(C)OC(=O)N(CCSc1cccs1)C1CCN(C(=O)C(F)(F)F)CC1,,ClCCl,,,,test
US20120157427A1,CNc1nc(Cl)ncc1Br.Cc1c(N)cnn1C>>CNc1nc(Nc2cnn(C)c2C)ncc1Br,,COCCO,,O=C(O)C(F)(F)F,,test
US20050176784A1,Fc1ccc(CBr)cn1.N#CC(C#N)CCC(F)(F)F>>N#CC(C#N)(CCC(F)(F)F)Cc1ccc(F)nc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050245563A1,Nc1ccc(Cl)cc1.O=CCCN1C(=O)c2ccccc2C1=O>>O=C1c2ccccc2C(=O)N1CCCNc1ccc(Cl)cc1,,CCOC(C)=O,ClCCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20110082164A1,CS(N)(=O)=O.Cc1noc(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1Nc1cccc(Cc2ccccc2)n1>>Cc1noc(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)c1Nc1cccc(Cc2ccccc2)n1,,C1CCOC1,,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US05198450,O=C(CCCc1ccc([N+](=O)[O-])cc1)N1CCSC1>>Nc1ccc(CCCC(=O)N2CCSC2)cc1,[Zn],O,,CC(=O)O,,test
US06008229,C/C(=C/COC(c1ccccc1)(c1ccccc1)c1ccccc1)c1ccc(C)c(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1C>>C/C(=C/CO)c1ccc(C)c(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1C,,CC(=O)O,,,,test
US20060089382A1,N#Cc1cnc2cc(OCCCN3CCOCC3)cc(OC3CCOCC3)c2c1O.O=P(Cl)(Cl)Cl>>N#Cc1cnc2cc(OCCCN3CCOCC3)cc(OC3CCOCC3)c2c1Cl,,CC#N,,,,test
US20110190269A1,CC(=O)CC(=O)c1ccc(F)c(Cl)c1.COc1cc(Nc2nnc(N)[nH]2)ccc1-n1cnc(C)c1>>COc1cc(Nc2nc3nc(C)cc(-c4ccc(F)c(Cl)c4)n3n2)ccc1-n1cnc(C)c1,,CC(=O)O,CCOCC,,,test
US20110028492A1,CC1(C=O)OCCO1.CC1(CNc2nc(-c3cc(N[C@@H]4CC[C@@H](N)CC4)ncc3Cl)ccc2F)CCOCC1>>CC1(CN[C@@H]2CC[C@@H](Nc3cc(-c4ccc(F)c(NCC5CCOCC5)n4)c(Cl)cn3)CC2)OCCO1,,ClCCl,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20110318842A1,CC1(C2OCCO2)C=CC(C#N)=CC1>>CC1(C2OCCO2)C=CC(CN)=CC1,,CCOCC,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US06960588B1,COC(=O)COCC#Cc1ccc(C#CCOCC(=O)O)cc1>>O=C(O)COCC#Cc1ccc(C#CCOCC(=O)O)cc1,,CO,,Cl,[Na+].[OH-],test
US05880188,O=Cc1sccc1Br.OCCO>>Brc1ccsc1C1OCCO1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US20160016948A1,NCC1CCOCC1.O=[N+]([O-])c1cnc(Br)cc1Br>>O=[N+]([O-])c1cnc(Br)cc1NCC1CCOCC1,,C1CCOC1,O,CCN(CC)CC,,test
US20070155743A1,CC(C)[C@@H](CN)C[C@H]1COC(C)(C)N1NC(=O)OC(C)(C)C.COCCCOc1ccccc1C(=O)O>>COCCCOc1ccccc1C(=O)NC[C@@H](C[C@H]1COC(C)(C)N1NC(=O)OC(C)(C)C)C(C)C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,[Na+].[OH-],test
US20050165065A1,NC1CCN(C(c2ccccc2)c2ccccc2)C1=O.O=C(O)CC(c1ccccc1)c1ccccc1>>O=C(CC(c1ccccc1)c1ccccc1)NC1CCN(C(c2ccccc2)c2ccccc2)C1=O,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20120322785A1,NCCO.O=C(Nc1cc2ccc(Br)cc2cn1)C1CC1>>O=C(Nc1cc2ccc(NCCO)cc2cn1)C1CC1,[Cu]I,,,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US05360822,CS(=O)(=O)Nc1ccc(F)c(C(=O)CBr)c1.c1ccc(CNCc2ccccc2)cc1>>CS(=O)(=O)Nc1ccc(F)c(C(=O)CN(Cc2ccccc2)Cc2ccccc2)c1,,CN(C)C=O,,O,,test
US20140112945A1,CC(C)(C)OC(=O)N[C@@H](CCC(=O)N1CCCCC1)C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](CCC(=O)N1CCCCC1)C(=O)O,[Pd],CO,,,,test
US20150252030A1,COC(=O)CBr.Cc1ccnc(C)c1O>>COC(=O)COc1c(C)ccnc1C,,CC#N,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US05925767,CCOC(=O)c1ccc2c(c1C)OCCS2>>Cc1c(C(=O)O)ccc2c1OCCS2,,CO,O,[Na+].[OH-],,test
US05190959,Nc1ccccc1OCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(Nc1ccccc1OCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1)c1ccccc1,,c1ccncc1,,,,test
US07071175B1,CCOC(=O)C(C)(Cc1ccc(NC(=O)OC(C)(C)C)nc1)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)Nc1ccc(CC(C)(C(=O)O)C(=O)OC(C)(C)C)cn1,,C1CCOC1,CCO,ClCCl,[Na+].[OH-],test
US04983211,CCC(=O)OC(=O)CC.CCOC(=O)C1C(O)=CC(=O)CC1c1ccc(OCc2ccccc2)cc1>>CCOC(=O)C1C(O)=C(C(=O)CC)C(=O)CC1c1ccc(OCc2ccccc2)cc1,CN(C)c1ccncc1,ClC(Cl)Cl,,c1ccncc1,,test
US20140031338A1,COC(=O)Cc1c(C)nc2c(c1-c1ccccc1)CCCC2.O=S(=O)(c1ccccc1)N1OC1c1ccccc1>>COC(=O)C(O)c1c(C)nc2c(c1-c1ccccc1)CCCC2,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20070208014A1,C=C[Mg]Br.CCOC(=O)C(=O)C(F)(F)F>>C=CC(O)(C(=O)OCC)C(F)(F)F,,C1CCOC1,,,,test
US05364881,CC(=O)OC(C)(C)C.N[C@@H](CCCNC(=O)OCc1ccccc1)C(=O)O>>CC(C)(C)OC(=O)[C@@H](N)CCCNC(=O)OCc1ccccc1,,O,,[O-][Cl+3]([O-])([O-])O,,test
US20040122057A1,CC(=O)O.CCO[C@@H](C(=O)NCc1ccc(/C(N)=N\C(=O)OCc2ccccc2)cc1)c1ccc(OC)cc1F>>CC(=O)O.CCO[C@@H](C(=O)NCc1ccc(C(=N)N)cc1)c1ccc(OC)cc1F,[Pd],CCO,,,,test
US20130040389A1,CCc1c(C(=O)NNC(=O)OC(C)(C)C)ccc2c1OCCO2.O>>CCc1c(C(=O)O)ccc2c1OCCO2.NN,,O,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20060004012A1,CC#CC(CC(=O)OCC)c1ccc(OCc2nc(-c3ccc(C(F)(F)F)cc3)oc2C)cc1>>CC#CC(CC(=O)O)c1ccc(OCc2nc(-c3ccc(C(F)(F)F)cc3)oc2C)cc1,,CCO,O,Cl,[K+].[OH-],test
US04159375,Nc1nncn1N.O=CC(=O)c1ccccc1Cl>>Clc1ccccc1-c1cnn2cnnc2n1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20070207997A1,NC(=O)c1cc2c(nc1N)[nH]c1ccccc12.O=C1CCC(=O)N1Br>>NC(=O)c1cc2c(nc1N)[nH]c1ccc(Br)cc12,,CC#N,CN(C)C=O,O,,test
US20130331377A1,CCCCc1cc(=O)[nH]c(SC)n1.N#Cc1cccc(N)c1>>CCCCc1cc(=O)[nH]c(Nc2cccc(C#N)c2)n1,,CCCCO,,,,test
US20100298316A1,C1CCNC1.O=Cc1ccc2nc(N3CCN(C4CC4)CC3)sc2c1>>c1cc2nc(N3CCN(C4CC4)CC3)sc2cc1CN1CCCC1,,C1CCOC1,CO,CC(=O)O,[BH3-]C#N.[Na+],test
US20070167521A1,CI.C[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@H]4[C@@]3(C)CC[C@H]3C(C)(C)[C@@H](O)[C@H](O)C[C@@]34C)[C@@H]2[C@H]1C>>COC(=O)[C@]12CC[C@@H](C)[C@H](C)[C@H]1C1=CC[C@H]3[C@@](C)(CC[C@H]4C(C)(C)[C@@H](O)[C@H](O)C[C@@]43C)[C@]1(C)CC2,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100022598A1,CCC(C)(C)Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c(CC(N)c2ccc(-c3ccc(F)cn3)cc2)n1>>CCC(C)(C)Cc1c[nH]c(CC(N)c2ccc(-c3ccc(F)cn3)cc2)n1,,CO,,Cl,,test
US04883815,O=C1CCC2=C(CCc3cc(F)ccc32)N1>>Fc1ccc2c(c1)CCC1=C2CCCN1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US04337256,Cc1ccc(-c2nccc3c(CCl)cccc23)cc1.[C-]#N>>Cc1ccc(-c2nccc3c(CC#N)cccc23)cc1,,CS(C)=O,,O,,test
US20070021353A1,O=S(=O)(Cl)C(F)(F)F.O[C@H](c1ccc(F)cc1)C(F)(F)F>>O=S(=O)(O[C@H](c1ccc(F)cc1)C(F)(F)F)C(F)(F)F,,CCOCC,,[H-].[Na+],,test
US20060040963A1,COC(OC)N(C)C.O=C1CCCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)C1>>CN(C)C=C1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CC1=O,,CN(C)C=O,,,,test
US20110251190A1,CC(C)(C)OC(=O)NC1=NC2(CS1)c1cc(-c3cccnc3F)ccc1Oc1ncc(C3=CCOCC3)cc12>>NC1=N[C@@]2(CS1)c1cc(-c3cccnc3F)ccc1Oc1ncc(C3=CCOCC3)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US05180723,CI.O=S(=O)(NC(Cc1ccccc1)c1ccccc1)c1ccc(CBr)cc1>>CN(C(Cc1ccccc1)c1ccccc1)S(=O)(=O)c1ccc(CBr)cc1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20030232869A1,CCOC(OCC)OCC.Cc1cc(Cl)ccc1Nc1c(C(=O)NN)cc2[nH]cnc2c1F>>Cc1cc(Cl)ccc1Nc1c(-c2nnco2)cc2[nH]cnc2c1F,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20120071534A1,CC(C)(C(=N)Nc1ccc(Br)cc1)c1ccccc1F.CCOC(=O)C(=O)CBr>>CCOC(=O)c1cn(-c2ccc(Br)cc2)c(C(C)(C)c2ccccc2F)n1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US05650415,CCOC(=O)c1cnc2c(F)ccc(F)c2c1Cl.N#Cc1ccccc1N>>CCOC(=O)c1cnc2c(F)ccc(F)c2c1Nc1ccccc1C#N,,CC(C)O,,,,test
US20100261719A1,C[C@H]1CN(c2c(C(O[SiH2]C(C)(C)C)(c3ccccc3)c3ccccc3)cc(C(=O)O)c(F)c2F)C[C@@H](C)O1>>C[C@H]1CN(c2c(CO)cc(C(=O)O)c(F)c2F)C[C@@H](C)O1,,C1COCCO1,,Cl,,test
US20090111800A1,CI.Cc1ccc(O)cc1Cl>>COc1ccc(C)c(Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060178527A1,CCOC(C)=NO.O=C(OCc1ccccc1)c1ccccc1F>>CCOC(C)=NOc1ccccc1C(=O)OCc1ccccc1,,CN(C)C=O,O,CC(C)(C)O[K],,test
US20150005329A1,COc1cc(F)ccc1-c1nc(Cl)ncc1F.CSCc1cccc(N)c1>>COc1cc(F)ccc1-c1nc(Nc2cccc(CSC)c2)ncc1F,,CCCCO,CCOC(C)=O,C1COCCO1,Cl,test
US20120130129A1,COc1cccc(/C=C/CCC(=O)O)c1OC>>COc1cccc(CCCCC(=O)O)c1OC,[Pd],CO,,CCOC(C)=O,,test
US20090042967A1,CC[C@H](NC(=O)OCc1ccccc1)C(=O)C1(C(=O)OC(C)(C)C)CC1>>CC[C@H](NC(=O)OCc1ccccc1)C(O)C1(C(=O)OC(C)(C)C)CC1,,CO,,[BH4-].[Na+],[Cl-].[NH4+],test
US05574061,CCCCCCCCCCCCN.Cc1ccc2c(c1N=C=O)OCCC2=O>>CCCCCCCCCCCCNC(=O)Nc1c(C)ccc2c1OCCC2=O,,CCOC(C)=O,,,,test
US20110183985A1,Brc1ncnc2[nH]cnc12.CC(N)c1cc(Cl)c2cccnc2c1N1CCC[C@H](O)C1>>CC(Nc1ncnc2[nH]cnc12)c1cc(Cl)c2cccnc2c1N1CCC[C@H](O)C1,,CCO,,CCN(C(C)C)C(C)C,,test
US20040102435A1,COc1ccc(-c2nc3c(C)c(C(=O)O)c(OC)cc3s2)cc1>>COc1ccc(-c2nc3c(C(=O)O)cc(OC)cc3s2)cc1,,O,,C1CCOC1,[Na+].[OH-],test
US07629363B2,Fc1ccc(CBr)c(F)c1.O=C1CC(Br)C(=O)N1.O=c1cc(O)c2ccccc2[nH]1>>O=c1[nH]c2ccccc2c(OCc2ccc(F)cc2F)c1Br,,CN(C)C=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US04985444,O=C1CSC(=S)N1.O=Cc1c(-c2ccccc2)nn2ccccc12>>O=C1NC(=S)SC1=Cc1c(-c2ccccc2)nn2ccccc12,,CCOC(C)=O,O,CC(=O)O,CC(=O)[O-].[Na+],test
US05116863,CN(C)CCCC1(O)c2ccccc2COc2ccc(CCOC(c3ccccc3)(c3ccccc3)c3ccccc3)cc21>>CN(C)CCC=C1c2ccccc2COc2ccc(CCOC(c3ccccc3)(c3ccccc3)c3ccccc3)cc21,,c1ccncc1,,O=P(Cl)(Cl)Cl,,test
US20100179109A1,COC(=O)c1ccc(CN(C)C(=O)OC(C)(C)C)cc1Br.OB(O)c1ccccc1>>COC(=O)c1ccc(CN(C)C(=O)OC(C)(C)C)cc1-c1ccccc1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20140142085A1,NC(=O)c1cc(-c2cccnc2[C@H](Cc2cc(F)cc(F)c2)NC(=O)Cn2nc(C(F)(F)F)c3c2CCCC3O)ccc1F>>NC(=O)c1cc(-c2cccnc2[C@H](Cc2cc(F)cc(F)c2)NC(=O)Cn2nc(C(F)(F)F)c3c2CCC=C3)ccc1F,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20130261128A1,CCOC(=O)C1(COc2cc(C)c(-c3ccc(-c4nc(C(F)(F)F)cn4COCC[Si](C)(C)C)c(Cl)c3)cn2)CCC1>>Cc1cc(OCC2(C(=O)O)CCC2)ncc1-c1ccc(-c2nc(C(F)(F)F)cn2COCC[Si](C)(C)C)c(Cl)c1,,CO,,[Na+].[OH-],,test
US20140323486A1,COC(=O)C(C)(C)Cc1ccc([N+](=O)[O-])cc1>>COC(=O)C(C)(C)Cc1ccc(N)cc1,,CO,,,,test
US20160021883A1,O=C1c2ccccc2C(=O)N1CCCc1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1>>NCCCc1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1,,CO,ClCCl,NN,O,test
US20160122342A1,C=CCc1c(N)cccc1C(=O)OC.CC(C)(C)OC(=O)NC1CCC(=O)CC1>>C=CCc1c(N[C@@H]2CC[C@@H](NC(=O)OC(C)(C)C)CC2)cccc1C(=O)OC,,ClCCCl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20060211730A1,COC(=O)C1(C)COCCC1=N[C@H](C)c1ccccc1>>COC(=O)C1(C)COCC[C@H]1N[C@H](C)c1ccccc1,,CC#N,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US07396844B1,BrCCCCCBr.CCOC(=O)c1ccc(N)cc1>>CCOC(=O)c1ccc(N2CCCCC2)cc1,,O,c1ccccc1,CCN(C(C)C)C(C)C,,test
US20130281505A1,CON=C1CCCCc2ccc(I)cc21>>CONC1CCCCc2ccc(I)cc21,,CC(=O)O,,[BH3-]C#N.[Na+],,test
US20040006081A1,C=CCN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)C1CCN(Cc2ccccc2)CC1>>C=CCN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)C1CCNCC1,,ClCCl,,CC(Cl)OC(=O)Cl,,test
US20150376136A1,COc1ccccc1C1(C)NC(=O)NC1=O.O=C(CBr)c1ccccc1>>COc1ccccc1C1(C)NC(=O)N(CC(=O)c2ccccc2)C1=O,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100168110A1,COc1ccc(OC)c2c1CCC2>>COc1ccc(O)c2c1CCC2,,ClCCl,,BrB(Br)Br,O,test
US20020198200A1,COC(=O)C(=NNS(=O)(=O)c1ccc(C)cc1)c1ccc(Cl)c(Cl)c1>>COC(=O)C(=[N+]=[N-])c1ccc(Cl)c(Cl)c1,,ClCCl,,CCN(CC)CC,,test
US20080300232A1,O=C(CCl)NC1CCN(Cc2ccccc2)CC1.Sc1cccc(Cl)c1>>O=C(CSc1cccc(Cl)c1)NC1CCN(Cc2ccccc2)CC1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20150065480A1,CC(C)(C)OC(=O)N1CCNCC1.N#Cc1c(Cl)c2ccccc2n(Cc2ccc(F)cc2)c1=O>>CC(C)(C)OC(=O)N1CCN(c2c(C#N)c(=O)n(Cc3ccc(F)cc3)c3ccccc23)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20080306090A1,Fc1ccc(N2CCNCC2)cc1.O=[N+]([O-])c1cccc(OCCCCCBr)c1>>O=[N+]([O-])c1cccc(OCCCCCN2CCN(c3ccc(F)cc3)CC2)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150158895A1,COc1cc2cncc(Cc3ccc4oc5ccccc5c4c3)c2cc1OC.O=C(OO)c1cccc(Cl)c1>>COc1cc2c[n+]([O-])cc(Cc3ccc4oc5ccccc5c4c3)c2cc1OC,,ClCCl,,,,test
US20160206616A1,COC(=O)C1=C(CBr)NC(c2nccs2)=N[C@H]1c1ccc(Cl)cc1Cl.O=C(O)CC[C@H]1CC(F)(F)CN1>>COC(=O)C1=C(CN2CC(F)(F)C[C@@H]2CCC(=O)O)NC(c2nccs2)=N[C@H]1c1ccc(Cl)cc1Cl,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080085890A1,COC=C1C(=O)NC(=O)c2ccc(Br)cc21.NCCN1CCNCC1>>O=C1NC(=O)c2ccc(Br)cc2/C1=C/NCCN1CCNCC1,,CCOCC,,CN(C)C=O,,test
US20070208048A1,BrBr.CCCCc1c(C)nc(Cl)nc1-c1ccccc1>>CCCCc1c(CBr)nc(Cl)nc1-c1ccccc1,,CC(=O)O,,,,test
US20100216860A1,COc1cccc2[nH]nc(N(COCC[Si](C)(C)C)S(=O)(=O)c3ccc(Cl)s3)c12.NS(=O)(=O)c1ccc(CBr)cc1>>COc1cccc2c1c(NS(=O)(=O)c1ccc(Cl)s1)nn2Cc1ccc(S(N)(=O)=O)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05374732,CCN(CC)CC.Cc1ccc(S(=O)(=O)O)c(C)n1>>CCN(CC)CC.Cc1ccc(S(=O)(=O)O)c(C)n1,,CC#N,,,,test
US20070281933A1,CCS(=O)(=O)N1CCC(c2n[nH]c3c(C(N)=O)cc(Br)cc23)CC1.OB(O)c1cccc(F)c1>>CCS(=O)(=O)N1CCC(c2n[nH]c3c(C(N)=O)cc(-c4cccc(F)c4)cc23)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20090306066A1,Cl.c1ccc(CN2CCC[C@H]2CN2CCCCC2)cc1>>C1CCN(C[C@@H]2CCCN2)CC1.Cl,,CO,,,,test
US20050043388A1,NNC(=O)c1ccc(OC(F)(F)F)cc1.O=C1Nc2ccc(I)cc2C1=O>>O=C1Nc2ccc(I)cc2C1=NNC(=O)c1ccc(OC(F)(F)F)cc1,,CC(=O)O,,,,test
US20120184553A1,COC(=O)c1cc(Br)ccc1O.N#C[Cu]C#N>>COC(=O)c1cc(C#N)ccc1O,,CN(C)C=O,,,,test
US20040082570A1,CC(C)(C)C(=O)OCn1c(=O)c2[nH]cnc2n(COC(=O)C(C)(C)C)c1=O.O=C1CCC(=O)N1Cl>>CC(C)(C)C(=O)OCn1c(=O)c2[nH]c(Cl)nc2n(COC(=O)C(C)(C)C)c1=O,,CCOC(C)=O,CN(C)C=O,,,test
US20130030012A1,CN1CCCn2c1cc(Cl)nc2=O.Cc1ccccc1CS>>Cc1ccccc1CSc1cc2n(c(=O)n1)CCCN2C,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20060111375A1,COc1cc2nccc(Cl)c2cc1OC.Oc1cc2cccnc2nc1-c1ccccc1>>COc1cc2nccc(Oc3cc4cccnc4nc3-c3ccccc3)c2cc1OC,CN(C)c1ccncc1,Clc1ccccc1Cl,,O,,test
US04794110,CNC.O=C(CCl)c1cccn1C(c1ccccc1)c1ccccc1F>>CN(C)CC(=O)c1cccn1C(c1ccccc1)c1ccccc1F.Cl,,CO,,,,test
US20150105399A1,C1CNCCN1.COc1c(Cl)ncnc1Cl>>COc1c(Cl)ncnc1N1CCNCC1,,O,,,,test
US20050272784A1,C1CCNCC1.COC(=O)c1ncoc1-c1ccc(Cl)nc1>>COC(=O)c1ncoc1-c1ccc(N2CCCCC2)nc1,,ClCCl,,,,test
US04237058,CCOC(=O)C(Cl)(Cl)C1OC(=O)CC(C)(C)C1Cl>>CCOC(=O)C(Cl)(Cl)C1OC(=O)C2C1C2(C)C,,C1CCOC1,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US20090069287A1,CC(C)c1cccc(C2(N)CNC2)c1.O=C(Cl)OCc1ccccc1>>CC(C)c1cccc(C2(N)CN(C(=O)OCc3ccccc3)C2)c1,,C1CCOC1,,CCN(CC)CC,Cl,test
US20130211075A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Cc1cc(Br)cnc1Br>>Cc1cc(Br)cnc1C1(O)CCN(C(=O)OC(C)(C)C)CC1,,Cc1ccccc1,O,CCCCCC,[Li]CCCC,test
US20030158245A1,CCOc1sc(C(=O)O)c2c1-c1c(cnn1C)CC2.N>>CCOc1sc(C(N)=O)c2c1-c1c(cnn1C)CC2,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20060100219A1,NCCN1CCNC1=O.O=S(=O)(Cl)c1cccc(Cl)c1Cl>>O=C1NCCN1CCNS(=O)(=O)c1cccc(Cl)c1Cl,,C1CCOC1,,CCN(CC)CC,,test
US20100075968A1,COC(=O)C1CN(C2CCN(C(=O)OC(C)(C)C)CC2)C(=O)N1C>>CN1C(=O)N(C2CCN(C(=O)OC(C)(C)C)CC2)CC1C(=O)O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20080275116A1,CC(C)(C)c1ccc(COc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2C=O)cc1.CCOP(=O)(CC#N)OCC>>CC(C)(C)c1ccc(COc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2C=CC#N)cc1,,C1CCOC1,,Cl,[Li+].[OH-],test
US20070197571A1,N#CCCCBr.Nc1ccccc1CN1CCC2(CC1)C(NC1CCCCC1)=NC(=O)N2c1cccc(F)c1>>N#CCCCNc1ccccc1CN1CCC2(CC1)C(NC1CCCCC1)=NC(=O)N2c1cccc(F)c1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160193218A1,COc1cc(N)c(C(N)=O)c(OC)c1.COc1ccc(NC2CCN(C(C)C)CC2)c(C=O)c1>>COc1ccc(NC2CCN(C(C)C)CC2)c(-c2nc3cc(OC)cc(OC)c3c(=O)[nH]2)c1,,CC(=O)N(C)C,,O=S([O-])O.[Na+],,test
US05891871,COC(=O)Cc1cc2c(cc1C(=O)c1ccccc1)OCO2.NN>>O=C1Cc2cc3c(cc2C(c2ccccc2)=NN1)OCO3,,CCO,,O,,test
US06252076B1,Br.CC(N)c1ccccc1.OCCBr>>Br.CC(NCCBr)c1ccccc1,,ClCCl,,,,test
US04812164,CCOc1nc(C(F)(F)C(F)(F)F)cc(=O)n1-c1cc(O)c(Cl)cc1F.COS(=O)(=O)OC>>CCOc1nc(C(F)(F)C(F)(F)F)cc(=O)n1-c1cc(OC)c(Cl)cc1F,,CC(C)=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20020193596A1,COC(=O)c1ccc(COc2cccnc2)cc1OS(=O)(=O)C(F)(F)F.Cc1ccccc1B(O)O>>COC(=O)c1ccc(COc2cccnc2)cc1-c1ccccc1C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090156612A1,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C[C@H]1CCCO.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C[C@H]1CCCOS(C)(=O)=O,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20060135578A1,COCOc1nn(-c2ccccc2)cc1/C=C/c1csc(C)n1.Cl>>Cc1nc(/C=C/c2cn(-c3ccccc3)nc2O)cs1.Cl,,CO,,,,test
US05130339,COc1cccc2c1CCC(C#N)C2=O>>COc1cccc2c1CCC(C#N)C2O,,CO,,[BH4-].[Na+],,test
US20110178077A1,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1.Oc1ccccc1>>O=C(Oc1ccccc1)N1CCCC1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090306078A1,COC(=O)c1ccnc(NC(=O)COc2ccc(Br)cc2Cl)c1>>O=C(COc1ccc(Br)cc1Cl)Nc1cc(C(=O)O)ccn1,,c1ccncc1,,[I-].[Li+],,test
US20050020592A1,Cn1c(O)nc(-c2ccncc2)c(N)c1=O.O=P(Cl)(Cl)Cl>>Cn1c(Cl)nc(-c2ccncc2)c(N)c1=O,,CCO,,,,test
US20110003795A1,CCOC(=O)C(C)c1ccc2c(c1)CCN2S(C)(=O)=O>>CC(C(=O)O)c1ccc2c(c1)CCN2S(C)(=O)=O,,C1CCOC1,O,[Li+].[OH-],,test
US20090156592A1,Cc1cc(C(F)(F)F)nn1CC(=O)N1CCC(C(N)=S)CC1.O=C(CBr)C1=NO[C@@H](c2ccccc2)C1>>Cc1cc(C(F)(F)F)nn1CC(=O)N1CCC(c2nc(C3=NO[C@@H](c4ccccc4)C3)cs2)CC1,,CCO,O,,,test
US05508288,Cn1ccc2cc(N)ccc21.O=C(O)c1ccnnc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cn1ccc2cc(NC(=O)Nc3ccnnc3)ccc21,,C1COCCO1,,CCN(CC)CC,,test
US04009169,Cc1cnc2c(c1)CCCC2C(N)=S.O=C(O)C(O)C(O)C(=O)O>>Cc1cnc2c(c1)CCCC2C(N)=S.O=C(O)C(O)C(O)C(=O)O,,CC(C)O,,,,test
US04654360,O=C(OO)c1cccc(Cl)c1.c1ccc(Sc2c[nH]c3ccccc23)cc1>>O=S(c1ccccc1)c1c[nH]c2ccccc12,,ClCCl,,,,test
US20110172237A1,N#Cc1ccc(OCCCBr)cc1.O=C(O[C@H]1CN2CCC1CC2)C1(c2ccccc2)CCCCCC1>>N#Cc1ccc(OCCC[N+]23CCC(CC2)[C@@H](OC(=O)C2(c4ccccc4)CCCCCC2)C3)cc1.[Br-],,CC#N,,,,test
US20090239924A1,CCCOC(=O)c1cc2c(o1)c(NC(=O)c1ccccc1[N+](=O)[O-])nn2C(=O)OCC>>Nc1ccccc1C(=O)Nc1[nH]nc2cc(C(=O)O)oc12,,CO,,[Na+].[OH-],,test
US20100093730A1,O=C(O)CN1CCCC(c2ccccc2)(c2ccccc2)C1=O.[H]/N=C(\NO)c1cccc(C(F)(F)F)c1>>O=C1N(Cc2nc(-c3cccc(C(F)(F)F)c3)no2)CCCC1(c1ccccc1)c1ccccc1,,CC(Cl)Cl,,CCN=C=NCCCN(C)C,Cl,test
US04638067,CNCC1CCNC1.O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O>>CNCC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,,CC#N,,,,test
US05665748,O=CCCc1ccc2oc(Cc3ccc4ccccc4c3)nc2c1.OCCO>>c1ccc2cc(Cc3nc4cc(CCC5OCCO5)ccc4o3)ccc2c1,,c1ccccc1,,,,test
US20130178486A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[Si](C)(C)CCOCn1ccc2c(CN)cncc21>>CC(C)(C)OC(=O)NCc1cncc2c1ccn2COCC[Si](C)(C)C,,ClCCl,,,,test
US20130059801A1,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)NCCC(=O)OC>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)NCCC(=O)O,,C1CCOC1,,Cl,[Na+].[OH-],test
US20060287522A1,N#CCc1ccccc1-c1ccc(C(=O)O)cc1.O=C(NCc1cccnc1)c1ccc2n1Cc1ccccc1NC2>>N#CCc1ccccc1-c1ccc(C(=O)N2Cc3ccc(C(=O)NCc4cccnc4)n3Cc3ccccc32)cc1,,C1COCCO1,,CN(C)C=O,O=S(Cl)Cl,test
US04031226,O=C(NCCCl)c1ccco1.O=c1[nH]c2ccccc2n1C1CCNCC1>>O=C(NCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1)c1ccco1,,CN(C)C=O,,[I-].[K+],,test
US20050176689A1,CCOC(=O)C=Cc1cccc(C#Cc2cc(C(C)C)c3c(c2)C(C)(C)CC(C)(C)O3)c1>>CC(C)c1cc(C#Cc2cccc(C=CC(=O)O)c2)cc2c1OC(C)(C)CC2(C)C,,C1CCOC1,CCO,[K+].[OH-],,test
US20140155451A1,COCCOC.FC(F)(F)c1ccn(-c2ncccc2Cl)n1.O=C(Cl)Cl>>COc1cc(C(=O)Cl)n(-c2ncccc2Cl)n1,,C1CCOC1,Cc1ccccc1,CC(C)[Mg]Cl,,test
US20060004108A1,CC1(C)C2CC[C@]1(C)C(=O)CC2=O.O=C=Nc1ccc(C(F)(F)F)cc1>>CC1(C)C2CC[C@]1(C)C(=O)C(C(=O)Nc1ccc(C(F)(F)F)cc1)C2=O,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US05830912,CCOC(=O)CC(C)=O.Oc1ccc(F)c(O)c1F>>Cc1cc(=O)oc2c(F)c(O)c(F)cc12,,CS(=O)(=O)O,,O,,test
US20150018422A1,CCOC(=O)CC(c1cccc(CO)c1)C1CC1.COc1ccc(F)c(-c2ccc(O)c(CCC(C)(C)C)c2)c1>>CCOC(=O)CC(c1cccc(COc2ccc(-c3cc(OC)ccc3F)cc2CCC(C)(C)C)c1)C1CC1,,C1CCOC1,Cc1ccccc1,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04617316,CC(C)I.O=[N+]([O-])c1ccc(-n2cccc2)c(O)c1>>CC(C)Oc1cc([N+](=O)[O-])ccc1-n1cccc1,,CC(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20040167149A1,COc1cccc2c1CC1CC2CN(Cc2ccccc2)C1.Cl>>COc1cccc2c1CC1CNCC2C1.Cl,[Pd],CO,,O=C[O-].[NH4+],,test
US20090209586A1,Nc1cccc(Oc2ccccc2)c1.O=[N+]([O-])c1ccccc1F>>O=[N+]([O-])c1ccccc1Nc1cccc(Oc2ccccc2)c1,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20030087922A1,COc1ccc(-c2ccnc(Cl)n2)c(OC)c1OC.Cc1cc(C)cc(N)c1>>COc1ccc(-c2ccnc(Nc3cc(C)cc(C)c3)n2)c(OC)c1OC,,CCOCC,,C1CCOC1,[H-].[Na+],test
US20120245169A1,Cc1cccc2cc(C(C)Nc3nc(Cl)nc4c3ncn4C3CCCCO3)n(-c3ccccc3)c(=O)c12>>Cc1cccc2cc(C(C)Nc3nc(Cl)nc4[nH]cnc34)n(-c3ccccc3)c(=O)c12,,CCO,Cl,O=C([O-])O.[Na+],,test
US20040266820A1,Cn1c(=O)cc(C(F)(F)F)c2cc(N)ccc21.O=C=Nc1ccccc1>>Cn1c(=O)cc(C(F)(F)F)c2cc(NC(=O)Nc3ccccc3)ccc21,,CN(C)C=O,,c1ccncc1,,test
US20110257100A1,NC1CC1.Nc1ccc(Oc2ccnc3cc(-c4cnn(CCN5CCCC5=O)c4)sc23)c(F)c1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ccc(Oc2ccnc3cc(-c4cnn(CCN5CCCC5=O)c4)sc23)c(F)c1)NC1CC1,,CN(C)C=O,,c1ccncc1,,test
US20080242685A1,CC(C)(C)OC(=O)N1CCC(=Cc2ccncc2[N+](=O)[O-])CC1>>CC(C)(C)OC(=O)N1CCC(Cc2ccncc2N)CC1,[Pd],CO,,,,test
US20160009683A1,CC(C)Br.Oc1ccccc1I>>CC(C)Oc1ccccc1I,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160221989A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1(C)CNC[C@@H]1O>>CC(C)(C)OC(=O)N1C[C@H](O)C(C)(C)C1,,C1CCOC1,,CCN(CC)CC,,test
US20160222033A1,CCOC(=O)CC#N.O=Cc1csc2nc(CCl)cc(=O)n12>>CCOC(=O)/C(C#N)=C/c1csc2nc(CCl)cc(=O)n12,C1CCNCC1,ClCCl,,,,test
US20100036130A1,Cc1ccc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)nc1-c1cccc(C(=O)O)c1>>Cc1ccc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)nc1-c1cccc(C(=O)O)c1,,O,,Cl,,test
US20090275537A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)[SiH2]OC(C)(C)C1CCC(=O)N1>>CC(C)(C)OC(=O)N1C(=O)CCC1C(C)(C)O[SiH2]C(C)(C)C,CN(C)c1ccncc1,CC#N,,,,test
US20110034438A1,CC(C)(C)OC(=O)[C@@H]1CCC(=O)N1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)[C@@H]1CCC(O)N1C(=O)OC(C)(C)C,,C1CCOC1,,CC(C)C[AlH]CC(C)C,,test
US20040254159A1,COC(=O)Cc1ccc2c(c1)NC(=O)c1ccc(Cl)cc1N2>>O=C1Nc2cc(CCO)ccc2NC2=C1CCC(Cl)=C2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130085141A1,CCI.O=S(=O)(c1ccc(Cl)c(C(F)(F)F)c1)N1CCN2C[C@H](O)C[C@H]2C1>>CCO[C@@H]1C[C@H]2CN(S(=O)(=O)c3ccc(Cl)c(C(F)(F)F)c3)CCN2C1,,C1CCOC1,,[H-].[Na+],,test
US05721245,CC(=O)OCC1CCn2c(c(C3=C(c4coc5ccccc45)C(=O)OC3=O)c3ccccc32)C1.C[Si](C)(C)N[Si](C)(C)C>>CC(=O)OCC1CCn2c(c(C3=C(c4coc5ccccc45)C(=O)NC3=O)c3ccccc32)C1,,ClC(Cl)Cl,,CO,,test
US20050009843A1,CC(C)(C)OC(=O)NCCC(=O)O.COc1ccc(Cn2nnnc2/C=C/c2c(N3CCNCC3)nc3cc(C(=O)Nc4nc(C(C)(C)C)cs4)ccn3c2=O)cc1>>COc1ccc(Cn2nnnc2/C=C/c2c(N3CCN(C(=O)CCNC(=O)OC(C)(C)C)CC3)nc3cc(C(=O)Nc4nc(C(C)(C)C)cs4)ccn3c2=O)cc1,,CN(C)C=O,ClCCl,Cl,,test
US20060100237A1,CC(C)(C)OC(=O)N1C[C@@H]2CC[C@H](Oc3cc(-n4cccn4)ccc3-c3nn[nH]n3)C[C@H]2C[C@H]1C(=O)O.Cl>>Cl.O=C(O)C1CC2CC(Oc3cc(-n4cccn4)ccc3-c3nn[nH]n3)CCC2CN1,,CCOCC,ClCCl,,,test
US04180679,Cc1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1C.O=C1CCC(=O)N1Br>>Cc1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1CBr,,ClC(Cl)(Cl)Cl,,,,test
US20010049371A1,COc1ccc(C(CC(=O)O)N2C(=O)c3ccccc3C2=O)cc1OC1CCCC1.NO>>COc1ccc(C(CC(=O)NO)N2C(=O)c3ccccc3C2=O)cc1OC1CCCC1,,C1CCOC1,,Cl,,test
US20070249614A1,CON.O=C1CC2(CCCCC2)Oc2ccccc21>>NC1CC2(CCCCC2)Oc2ccccc21,Cl,CO,,c1ccncc1,,test
US20140275064A1,CN(C)/C=N/c1ccc2nc(C#N)sc2c1C#N.COc1cc(N)cc(OC)c1OC>>COc1cc(Nc2ncnc3ccc4nc(C#N)sc4c23)cc(OC)c1OC,,CCOC(C)=O,ClCCl,[Br-].[K+],,test
US20160096835A1,CCN(CC)S(=O)(=O)c1ccc(NN)nc1.O=C(n1ccnc1)n1ccnc1>>CCN(CC)S(=O)(=O)c1ccc2n[nH]c(=O)n2c1,,C1CCOC1,O,,,test
US05716936,CC(C)(C)OC(=O)C1CC(S(C)(=O)=O)C(c2ccccc2F)N1C(=O)CNC(=O)Nc1cccc(C(=O)OCc2ccccc2)c1>>CC(C)(C)OC(=O)C1CC(S(C)(=O)=O)C(c2ccccc2F)N1C(=O)CNC(=O)Nc1cccc(C(=O)O)c1,[Pd],CCO,,,,test
US20040209921A1,Cc1cc(C(F)(F)F)cnc1C.O=C(OO)c1cccc(Cl)c1>>Cc1cc(C(F)(F)F)c[n+]([O-])c1C,,ClCCl,,O=C([O-])O.[Na+],,test
US20040097555A1,CC(C)(C)c1ccc(-c2nc(N)sc2-c2ccncc2)cc1.O=C(Cl)c1ccccc1>>CC(C)(C)c1ccc(-c2nc(NC(=O)c3ccccc3)sc2-c2ccncc2)cc1,CN(C)c1ccncc1,CC(=O)N(C)C,,O=C([O-])O.[Na+],,test
US20160235870A1,CC(C)(C)OC(=O)CN1CCN(CC(=O)OC(C)(C)C)CCN(CC(O)CCc2ccc([N+](=O)[O-])cc2)CC1>>O=C(O)CN1CCN(CC(=O)O)CCN(CC(O)CCc2ccc([N+](=O)[O-])cc2)CC1,,O=C(O)C(F)(F)F,,,,test
US20080292585A1,CCCCCN=C=O.CN(C)CCN1C(=O)c2cccc3cc4cccc(N)c4c(c23)C1=O>>CCCCCNC(=O)Nc1cccc2cc3cccc4c3c(c12)C(=O)N(CCN(C)C)C4=O,,CC#N,,CO,ClCCl,test
US20140323537A1,CC(C)c1cc(-c2nn(C3CCCCO3)cc2CN(C)CCN(C)C(=O)OC(C)(C)C)cc(C(C)C)c1>>CNCCN(C)Cc1c[nH]nc1-c1cc(C(C)C)cc(C(C)C)c1,,C1COCCO1,,Cl,,test
US20060074075A1,CCOC(=O)C(C(=O)OCC)=C(Nc1ccccc1)SC>>CCOC(=O)c1c(SC)nc2ccccc2c1O,,Clc1ccccc1Cl,,,,test
US20110034452A1,CCNCC.Clc1cc(Cl)c(Cl)nn1>>CCN(CC)c1cc(Cl)nnc1Cl,,Cc1ccccc1,,CCOC(C)=O,O,test
US20070082912A1,CCOC(=O)c1cncc(-n2c(C)ccc2-c2cc(Cl)ccc2O)c1.Fc1ccc(CBr)c(F)c1>>CCOC(=O)c1cncc(-n2ccc(C)c2-c2cc(Cl)ccc2OCc2ccc(F)cc2F)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20130289047A1,FC(F)(F)c1cccc(N2CCN(CCCl)CC2)c1.Sc1nnc(-c2ccncc2)o1>>FC(F)(F)c1cccc(N2CCN(CCSc3nnc(-c4ccncc4)o3)CC2)c1,,CC#N,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US04956382,CNCCc1ccc(NS(C)(=O)=O)cc1.Cc1c(CCl)oc2ccc([N+](=O)[O-])cc12>>Cc1c(CN(C)CCc2ccc(NS(C)(=O)=O)cc2)oc2ccc([N+](=O)[O-])cc12,,CCO,,,,test
US20040092550A1,CCOC(=O)C1CC1[C@H]1C[C@@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(=O)OC)c2cc(C(F)(F)F)ccc2N1C(=O)OC(C)C>>COC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@@H]1C[C@H](C2CC2CO)N(C(=O)OC(C)C)c2ccc(C(F)(F)F)cc21,,CO,,[BH4-].[Na+],,test
US20100197655A1,CC(C)(C)n1ncc(-c2cc(Cl)ccc2O)c1NC(=O)C(F)(F)F.COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc(F)c(C#N)c2)c(OC)c1>>COc1ccc(CN(c2ncns2)S(=O)(=O)c2ccc(Oc3ccc(Cl)cc3-c3cnn(C(C)(C)C)c3NC(=O)C(F)(F)F)c(C#N)c2)c(OC)c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04431647,C=C1CC(=O)O1.CN[C@@H]1Cc2ccccc2[C@H]1O>>CC(=O)CC(=O)N(C)[C@@H]1Cc2ccccc2[C@H]1O,,CCO,,,,test
US20090105474A1,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1N,[Fe],CC(=O)O,,CO,,test
US20150005279A1,Cc1c(N)cccc1B1OC(C)(C)C(C)(C)O1.O=C(O)c1nccs1>>Cc1c(NC(=O)c2nccs2)cccc1B1OC(C)(C)C(C)(C)O1,,ClCCl,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080161295A1,O=S(Cl)Cl.O=S1(=O)Nc2ccccc2CN1CCCO>>O=S1(=O)Nc2ccccc2CN1CCCCl,,ClCCl,,CN(C)C=O,,test
US20140187554A1,CC(C)(C)OC(=O)N1CCC(N2CCc3cc(Br)ccc32)CC1.O=Cc1ccncc1>>Brc1ccc2c(c1)CCN2C1CCN(Cc2ccncc2)CC1,,CO,ClCCl,O=C(O)C(F)(F)F,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04400198,CCC1(COCc2ccccc2)CC(=O)C(C)(C)O1.OCCO.c1ccccc1>>CCC1(COCc2ccccc2)CC(C2COCCO2)C(C)(C)O1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20110201599A1,COc1cc(Br)nc2c1ccn2C(=O)c1ccccc1>>COc1cc(Br)nc2[nH]ccc12,,CO,,[Na+].[OH-],,test
US04729847,CCCCCCC(C)OS(=O)(=O)c1ccc(C)cc1.Oc1ccc(O)c(-c2ccccc2COCc2ccccc2-c2cc(O)ccc2O)c1>>CCCCCCC(C)Oc1ccc(O)cc1,,O,,CCO,[Na+].[OH-],test
US20030060466A1,N#Cc1c(Cl)nc(NCCO)nc1NCC1CC1.c1ccc(N2CCNCC2)cc1>>N#Cc1c(NCC2CC2)nc(NCCO)nc1N1CCN(c2ccccc2)CC1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20110065681A1,CC(C)(C)[Si](C)(C)Cl.OC[C@H](O)c1ccc(C(F)F)nc1>>CC(C)(C)[Si](C)(C)OC[C@H](O)c1ccc(C(F)F)nc1,,ClCCl,,O,c1c[nH]cn1,test
US20130281657A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCCCNc1ncc(C=O)s1>>C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCCCNc1ncc(C=O)s1,,C1COCCO1,Cl,CCOCC,,test
US09133235B2,C[Si](C)(C)N[Si](C)(C)C.c1c[nH]cn1>>C[Si](C)(C)n1ccnc1,,Cc1ccccc1,,,,test
US20140155415A1,Clc1ccccc1Br.O=S(=O)(N=Cc1cc2ccccc2s1)c1ccc2c(c1)OCCCO2>>O=S(=O)(NC(c1cc2ccccc2s1)c1ccccc1Cl)c1ccc2c(c1)OCCCO2,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US06797726B1,CS(=O)(=O)Cl.OCCOCCc1ccc2sccc2c1>>CS(=O)(=O)OCCOCCc1ccc2sccc2c1,,ClCCl,O,Cl,c1ccncc1,test
US20120094964A1,COC(=O)c1ccc(S(=O)(=O)Cl)cc1.Nc1ncc(C(F)(F)F)cc1Cl>>COC(=O)c1ccc(S(=O)(=O)Nc2ncc(C(F)(F)F)cc2Cl)cc1,,c1ccncc1,,,,test
US20140371278A1,C=CCC1(S(=O)(=O)Nc2cc3scnc3c(F)c2Nc2ccc(Br)cc2Cl)CC1.C[N+]1([O-])CCOCC1.O=[Os](=O)(=O)=O>>O=S(=O)(Nc1cc2scnc2c(F)c1Nc1ccc(Br)cc1Cl)C1(CC(O)CO)CC1,O=[Os](=O)(=O)=O,,,C1CCOC1,O,test
US03987091,CC(=O)OC(C)=O.CCCCCC(CCCN)OC1CCCCO1>>CCCCCC(CCCNC(C)=O)OC1CCCCO1,,c1ccncc1,,,,test
US20160235870A1,CCOC(=O)C(CCCc1ccc([N+](=O)[O-])cc1)C(=O)OCC>>O=C(O)CCCCc1ccc([N+](=O)[O-])cc1,,CC(=O)O,Cl,,,test
US06300352B1,COC(=O)[C@@H](Oc1ccc(Br)cc1)C(C)C>>CC(C)[C@@H](CO)Oc1ccc(Br)cc1,,CCO,,[BH4-].[Na+],,test
US04528311,C=C(C)C(=O)Cl.CC(C)(C)c1cc(CCCO)cc(-n2nc3ccc(Cl)cc3n2)c1O>>CC=CC(=O)OCCCc1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1,,ClCCl,,CCN(CC)CC,,test
US04496567,BrCc1cccc(Br)c1.CNC>>CN(C)Cc1cccc(Br)c1,,c1ccccc1,,Cl,,test
US20160221994A1,Cc1cc(Cl)c2c(c1)CC(CN=[N+]=[N-])O2>>Cc1cc(Cl)c2c(c1)CC(CN)O2,,CCO,,,,test
US20050182103A1,C1CCNCC1.Cc1ccc(-c2cc(C#N)c(Cl)nc2-c2ccc(Cl)cc2Cl)cc1>>Cc1ccc(-c2cc(C#N)c(N3CCCCC3)nc2-c2ccc(Cl)cc2Cl)cc1,,Cc1ccccc1,,,,test
US20060094708A1,CC(=NO)c1nc(-c2ccc(C[C@@H](CCO)NC(=O)c3ccc(OC(C)C)c(Cl)c3)cc2)cn1C.CC(C)(C)[Si](C)(C)OCCBr>>CC(C)Oc1ccc(C(=O)N[C@H](CCO)Cc2ccc(-c3cn(C)c(C4(C)OCCO4)n3)cc2)cc1Cl,,CCOC(C)=O,,CN(C)C=O,[H-].[Na+],test
US20080132477A1,COC(=O)[C@H](Cc1cccc(OCc2ccccc2)c1)NC(=O)OC(C)(C)C>>COC(=O)[C@H](Cc1cccc(O)c1)NC(=O)OC(C)(C)C,[Pd],CCO,,,,test
US20130184254A1,Clc1ncncc1I.OCC(F)(F)F>>FC(F)(F)COc1ncncc1I,,C1CCOC1,CCOC(C)=O,[H-].[Na+],[Cl-].[NH4+],test
US20060229286A1,CI.O=C(O)c1c[nH]c2ccccc12>>Cn1cc(C(=O)O)c2ccccc21,,CN(C)C=O,,O,[H-].[Na+],test
US20090258876A1,Nc1ccc(Oc2cncnc2)nc1.O=C(O)c1c[nH]c2ccccc12>>O=C(Nc1ccc(Oc2cncnc2)nc1)c1c[nH]c2ccccc12,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20110003738A1,C=CC(=O)OCC.CCOC(=O)Cc1ccccn1>>O=C1CCN2CCCCC2C1,O=[Pt]=O,CCO,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20110053921A1,Cn1ccc(CCl)n1.O=C1Nc2cnc(Cl)nc2N2CCOCC12>>Cn1ccc(CN2C(=O)C3COCCN3c3nc(Cl)ncc32)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110021351A1,COC(=O)c1nccnc1NC(=O)Cc1c(C(F)(F)F)nn(C)c1OC(F)F>>Cn1nc(C(F)(F)F)c(-c2c(O)c3nccnc3[nH]c2=O)c1OC(F)F,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20050153957A1,Cc1c(C)c(C)c2c(c1C)CC(=NO)C2=O.O=C(Cl)c1ccccc1>>Cc1c(C)c(C)c2c(c1C)CC(NC(=O)c1ccccc1)C2=O,,ClCCl,,CCN(CC)CC,,test
US20140018380A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CC1(C)OB(c2ccc3c(c2)CCN3)OC1(C)C>>CC(C)(C)OC(=O)N1CCC(N2CCc3cc(B4OC(C)(C)C(C)(C)O4)ccc32)CC1,,CC(=O)O,,O=C([O-])O.[Na+],,test
US20030166932A1,CCOC(=O)CCC(C)(C)c1ccc(OC)c(C)c1>>COc1ccc(C(C)(C)CCC(=O)O)cc1C,,O,,CCO,[K+].[OH-],test
US05650428,CCCC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C(=O)O.CCOC(=O)Cc1ccc(N)cc1>>CCCC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C(=O)Nc1ccc(CC(=O)OCC)cc1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05952368,Cc1ccc(C(=O)c2ccc(Cc3ccc([N+](=O)[O-])cc3)n2C)c(C)c1>>Cc1ccc(C(=O)c2ccc(Cc3ccc(N)cc3)n2C)c(C)c1,[Pd],CCOC(C)=O,,,,test
US20010046975A1,CCCCCCC(C)NCC.C[Si](C)(C)c1cccc(Cl)c1C(=O)Cl>>CCCCCCC(C)N(CC)C(=O)c1c(Cl)cccc1[Si](C)(C)C,,Cc1ccccc1,,CCN(CC)CC,,test
US05624942,Cc1cc(Cl)nc(OCc2ccsc2)c1.Oc1cccc(C(F)(F)F)c1>>Cc1cc(OCc2ccsc2)nc(Oc2cccc(C(F)(F)F)c2)c1,[Cu]I,CN(C)C=O,,[H-].[Na+],,test
US20160046610A1,CCCc1ccc(CBr)cc1.O=c1[nH][nH]c2ccccc12>>CCCc1ccc(Cn2[nH]c(=O)c3ccccc32)cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20110070190A1,Nc1ccc(B(O)O)cn1.O=c1ncn(Cc2ccc(Cl)cc2)c2cc(Br)sc12>>Nc1ccc(-c2cc3c(s2)c(=O)ncn3Cc2ccc(Cl)cc2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20100152165A1,BrCCOc1ccccc1.CCOC(=O)c1cccc2c1CCCN2>>CCOC(=O)c1cccc2c1CCCN2CCOc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,[I-].[K+],test
US20100093955A1,C=C.OCC1CC2C=CC1C2>>C=C.OCC1CC2C=CC1C2,,Cc1ccccc1,,,,test
US20100099681A1,COC(=O)c1ccccc1Nc1c(-c2ccn3ncnc3c2)c(C)nn1-c1ccccc1C>>Cc1ccccc1-n1nc(C)c(-c2ccn3ncnc3c2)c1Nc1ccccc1C(=O)O,,C1COCCO1,O,Cl,[Na+].[OH-],test
US20100179325A1,COC(=O)C12CC3CC(C1)C(NC(=O)N1CCOc4ccccc41)C(C3)C2>>O=C(NC1C2CC3CC1CC(C(=O)O)(C3)C2)N1CCOc2ccccc21,,C1CCOC1,,Cl,[Na+].[OH-],test
US20120190665A1,CCI.Oc1ccc(Cl)cc1Br>>CCOc1ccc(Cl)cc1Br,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04168315,BrBr.O=C(Cc1ccc(Cl)cc1)c1ccc(Cl)cc1>>O=C(c1ccc(Cl)cc1)C(Br)c1ccc(Cl)cc1,,CCOCC,,ClC(Cl)Cl,,test
US20140005222A1,COC(=O)c1cc(C)c(NC(=O)c2cc(N3CCC(O)CC3)nc3ccccc23)c(C)c1>>Cc1cc(C(=O)O)cc(C)c1NC(=O)c1cc(N2CCC(O)CC2)nc2ccccc12,,C1CCOC1,,CO,[Na+].[OH-],test
US20080138741A1,C=C(C)C(=O)NCCC[N+](C)(C)C.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>C=C(C)C(=O)NCCC[N+](C)(C)C.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,O,,[Cl-].[Na+],,test
US20080249093A1,COC(=O)C1Cc2ccc(-c3noc(-c4cnc(OC(C)C)c(Cl)c4)n3)c(C)c2C1>>Cc1c(-c2noc(-c3cnc(OC(C)C)c(Cl)c3)n2)ccc2c1CC(C(=O)O)C2,,C1CCOC1,O,[Li+].[OH-],,test
US20010034343A1,CC(C)(C)OC(=O)N1CCCN(c2nc3ccccc3[nH]2)CC1.Fc1ccc(CBr)cc1>>Fc1ccc(Cn2c(N3CCCNCC3)nc3ccccc32)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20120053173A1,CC(=O)c1cc(OCc2ccccc2)ccc1O.CC(C)C(=O)CBr>>Cc1c(C(=O)C(C)C)oc2ccc(OCc3ccccc3)cc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04595535,Cc1nc(Cc2ccccc2[N+](=O)[O-])n[nH]1>>Cc1nc(Cc2ccccc2N)n[nH]1,[Pd],CCO,,,,test
US07531553B2,C=O.O=[N+]([O-])c1cc(OCC2CCCN2)cc(C(F)(F)F)c1>>CN1CCC[C@@H]1COc1cc([N+](=O)[O-])cc(C(F)(F)F)c1,,CC#N,,CC(=O)O,[BH3-]C#N.[Na+],test
US20060160803A1,COCCNC(=O)c1cc([N+](=O)[O-])cc(C(F)(F)F)c1>>COCCNC(=O)c1cc(N)cc(C(F)(F)F)c1,[Pd],CCOC(C)=O,,,,test
US04495104,COC(=O)CCCCCCCCCCCCC1=C(C)C(=O)C(OC)=C(OC)C1=O>>COC1=C(OC)C(=O)C(CCCCCCCCCCCCC(=O)O)=C(C)C1=O,,CCOCC,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20120010163A1,COC(=O)c1c(C)cc2c(c1O)[C@]1(O)C(=O)c3cc4c(c(O)c3C(=O)[C@]1(OC)[C@H](O)C2)C(=O)C=C(NC1OC(C)C(OC)C(O)C1OC)C4=O>>COC12CCc3cc(C)c(C(=O)O)cc3C1C(=O)c1cc3c(cc1C2=O)C(=O)C=CC3=O,,CS(C)=O,,[Cl-].[Li+],,test
US20120208844A1,BrC(Br)(Br)Br.COC(=O)[C@@H]1CC[C@H](CO)C1>>COC(=O)[C@@H]1CC[C@H](CBr)C1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US07566784B2,Nc1nccc2[nH]cc(-c3ccc([N+](=O)[O-])cc3)c12>>Nc1ccc(-c2c[nH]c3ccnc(N)c23)cc1,O=[Pt],CO,,[H][H],,test
US20120295885A1,CC(C)(C)c1cc(F)c2c(=O)[nH]ncc2c1.N#Cc1cn(-c2cccc(Br)c2C=O)nc1Nc1ccc(C(=O)N2CCOCC2)cc1>>CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)c(Nc5ccc(C(=O)N6CCOCC6)cc5)n4)c3)ncc2c1,,CS(C)=O,,O=C([O-])O.[Na+],,test
US20090286768A1,N.OC1CC(c2nc(I)c3c(Cl)nccn23)C1>>Nc1nccn2c([C@@H]3C[C@H](O)C3)nc(I)c12,,CC(C)O,,,,test
US20160155949A1,CC1(C)OB(c2cccc(-c3cnc4c(c3)c3ccccc3c3cccnc34)c2)OC1(C)C.Clc1ccc2ccc3ccc(-c4ccccc4)nc3c2n1>>c1ccc(-c2ccc3ccc4ccc(-c5cccc(-c6cnc7c(c6)c6ccccc6c6cccnc67)c5)nc4c3n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,Cc1ccccc1,CCO,O=C([O-])[O-].[Na+].[Na+],test
US05973168,CN(C)c1ccc(C(c2ccc(N(C)C)cc2)c2ccc(N(C)C)cc2C(=O)O)cc1>>CN(C)c1ccc(C2(c3ccc(N(C)C)cc3)OC(=O)c3cc(N(C)C)ccc32)cc1,,O,,[Na+].[OH-],,test
US20120208819A1,COC(=O)c1c(C#N)ccnc1Cl>>COC(=O)c1c(CN)ccnc1Cl,[Pt],CO,,,,test
US20100280001A1,CCCCc1nc2c(N)nc3ccccc3c2n1CCCN.CN1CCC(=O)CC1>>CCCCc1nc2c(N)nc3ccccc3c2n1CCCNC1CCN(C)CC1,,CN1CCCC1=O,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070015783A1,O=C1C(Cc2ccccc2)NC2(CCNCC2)N1Cc1ccccc1.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)N1CCC2(CC1)NC(Cc1ccccc1)C(=O)N2Cc1ccccc1,,Cc1ccccc1,,,,test
US20090005426A1,COc1cc(OC)cc(C(=O)N[C@@H]2[C@H](O)[C@@H](CO)O[C@H]2n2cnc3c(NCc4cccc5ccccc45)ncnc32)c1.NCc1cccs1.O=C(O)c1ccccc1O>>NC(=O)c1cccc(O)c1,,CCOC(C)=O,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
US20040264263A1,CC(C)=CC(=O)N(C)C.Cc1ccc(CC#N)cc1>>Cc1ccc(C(C#N)C(C)(C)CC(=O)N(C)C)cc1,,C1CCOC1,CN(C)P(=O)(N(C)C)N(C)C,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05424481,Cc1ccc(S(C)(=O)=O)cc1.O=[N+]([O-])O>>Cc1ccc(S(C)(=O)=O)cc1[N+](=O)[O-],,O=S(=O)(O)O,,,,test
US20010006969A1,C=CCNc1nc(N)nc2ccc([N+](=O)[O-])cc12.CC(=O)OC(C)=O>>C=CCNc1nc(NC(C)=O)nc2ccc([N+](=O)[O-])cc12,,CC#N,,CCN(CC)CC,O,test
US20090275037A1,CCCC(C(=O)O)N(C)C.NC(=O)c1ccccc1Nc1ccccc1>>CC(CCc1nc(=O)c2ccccc2n1-c1ccccc1)N(C)C,,ClC(Cl)Cl,,O=S(Cl)Cl,,test
US20060257987A1,COC(=O)CCc1ccc(OCCC(C)Oc2ccc(OC(F)(F)F)cc2C(=O)c2ccccc2)cc1C>>Cc1cc(OCCC(C)Oc2ccc(OC(F)(F)F)cc2C(=O)c2ccccc2)ccc1CCC(=O)O,,CCO,,[Na+].[OH-],,test
US20070149600A1,COc1ccc([C@@]23CCC(=O)C[C@@H]2CN(C)C3)cc1OC.[NH4+]>>COc1ccc([C@@]23CC[C@H](N)C[C@@H]2CN(C)C3)cc1OC,,CO,,[BH3-]C#N.[Na+],,test
US20130274255A1,CCOC(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C1CCc2sccc21>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1Cc2sccc2C1=O,,CCOC(C)=O,O,Cl,[H-].[Na+],test
US20120208819A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1nccs1>>CC(C)(C)OC(=O)NCc1nccs1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20040167118A1,CC(C)(C)OC(=O)N[C@@H](CNC(=O)C(C)(C)C)C(=O)N1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1.Cl>>CC(C)(C)C(=O)NC[C@H](N)C(=O)N1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1.Cl,,CCOC(C)=O,,,,test
US20120165309A1,N[C@@H]1CC[C@@H](Nc2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)CC1.OCn1nnc2ccccc21>>CN(c1nc(N2CCOCC2)nc(-n2c(C(F)F)nc3ccccc32)n1)[C@@H]1CC[C@@H](N)CC1,,CCO,,[BH4-].[Na+],,test
US20020042409A1,CCI.O=C(c1cc2nccc(Cl)c2s1)N1CCC[C@@H]1CO>>CCOC[C@H]1CCCN1C(=O)c1cc2nccc(Cl)c2s1,,CN(C)C=O,,[H-].[Na+],,test
US04294960,CCCCC(CCC)ON=C(C(=O)NC1C(=O)N2C(C(=O)O)=CCS[C@H]12)c1csc(NC=O)n1>>CCCCCCCCON=C(C(=O)NC1C(=O)N2C(C(=O)O)=CCS[C@H]12)c1csc(N)n1,,CO,,C1CCOC1,Cl,test
US20090203690A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(Cc1ccccc1)c1ccc2[nH]ncc2c1>>CC(C)(C)OC(=O)n1ncc2cc(C(=O)Cc3ccccc3)ccc21,,ClCCl,,CN(C)c1ccccn1,,test
US20150141396A1,CN(C)C(=O)[C@@H]1CC[C@@H](n2cc(-c3cnc(-c4cccc(-c5cnn(C)c5)c4)nc3)cn2)CC1>>CN(C)C(=O)C1CCC(n2cc(-c3cnc(-c4cccc(-c5cnn(C)c5)c4)nc3)cn2)CC1,,C1CCOC1,CCO,,,test
US20040162442A1,CNC.C[Si](C)(C)OC(=O)/C=C/CBr>>CN(C)C/C=C/C(=O)O,,C1CCOC1,,,,test
US20090298807A1,CC(C)(C)OC(=O)N(Cc1ccc(OCCN2CCC3(CC2)CN(C(=O)c2nc4ccccc4s2)CCO3)cc1)C[C@H](O)c1ccc(O)c2[nH]c(=O)sc12>>O=C(c1nc2ccccc2s1)N1CCOC2(CCN(CCOc3ccc(CNC[C@H](O)c4ccc(O)c5[nH]c(=O)sc45)cc3)CC2)C1.O=CO,,ClCCl,,Cc1ccccc1,O=C(O)C(F)(F)F,test
US06150373,CCNCC.CS(=O)(=O)OCCc1cccc(N2C(=O)N(c3ccc(Cl)cc3Cl)Cc3cnc(Nc4ccccc4)nc32)c1>>CCN(CC)CCc1cccc(N2C(=O)N(c3ccc(Cl)cc3Cl)Cc3cnc(Nc4ccccc4)nc32)c1,,CCO,,,,test
US20110071097A1,CC(=O)c1ccc2c(c1)OCO2.NO>>CC(=NO)c1ccc2c(c1)OCO2,,CCO,,Cl,[Na+].[OH-],test
US05958954,CCOC(=O)c1ccc(C#Cc2cc3c(cc2F)SC(C)(C)C=C3c2ccc(C)s2)cc1>>Cc1ccc(C2=CC(C)(C)Sc3cc(F)c(C#Cc4ccc(C(=O)O)cc4)cc32)s1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20040029928A1,CCOC(=O)/C=C(/c1ccccc1)c1cccc(N)c1.COc1ccc(C(=O)Cl)cc1>>COc1ccc(C(=O)Nc2cccc(/C(=C\C(=O)O)c3ccccc3)c2)cc1,,c1ccncc1,,CCOC(C)=O,Cl,test
US06274735B1,COc1ccccc1COCCCOc1ccc([C@H]2CCN(C(=O)OC(C)(C)C)C[C@@H]2OCc2ccc3ccc(OCCN4CCN(C)CC4)cc3c2)cc1>>COc1ccccc1COCCCOc1ccc([C@H]2CCNC[C@@H]2OCc2ccc3ccc(OCCN4CCN(C)CC4)cc3c2)cc1,,CO,,Cl,,test
US20040176444A1,CCOC(=O)[C@H](Cc1ccc(O)cc1)OCC.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)[C@H](Cc1ccc(OS(=O)(=O)C(F)(F)F)cc1)OCC,,ClCCl,,,,test
US06476030B1,Cc1ccc(S(=O)(=O)Cl)cc1.O=C1N=NC(CO)=C1c1ccccc1F>>Cc1ccc(S(=O)(=O)Oc2n[nH]c(CO)c2-c2ccccc2F)cc1,,ClCCl,,CCN(CC)CC,,test
US20160083349A1,C[C@H](N[S@](=O)C(C)(C)C)c1cc2cc(Cl)ccc2nc1Cl.Cl>>C[C@H](N)c1cc2cc(Cl)ccc2[nH]c1=O.Cl,,Cl,,C1COCCO1,,test
US05891909,Cc1cc(O)cc(OS(=O)(=O)c2cccc(Cl)c2Cl)c1.OCCCO>>Cc1cc(OCCCO)cc(OS(=O)(=O)c2cccc(Cl)c2Cl)c1,,C1CCOC1,CCCCCC,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20080146625A1,COC(=O)c1ccc(Cn2ccc(N)n2)cc1.CS(=O)(=O)c1ccc(/C(=N\OC2CCCC2)C(=O)O)cc1Cl>>COC(=O)c1ccc(Cn2ccc(NC(=O)/C(=N/OC3CCCC3)c3ccc(S(C)(=O)=O)c(Cl)c3)n2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100324068A1,COC(=O)Cc1cc(F)c(O)c(F)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)Cc1cc(F)c(OS(=O)(=O)C(F)(F)F)c(F)c1,,ClCCl,,CCN(CC)CC,,test
US20110218197A1,COc1ccc(CN)cc1.FC(F)(F)c1cc(Cl)nc(Cl)c1>>COc1ccc(CNc2cc(C(F)(F)F)cc(Cl)n2)cc1,,c1ccncc1,,,,test
US20150141406A1,COC(=O)c1c(I)ccnc1OC>>COc1nccc(I)c1C(=O)O,,CO,,[Na+].[OH-],,test
US20070167430A1,CN(Cc1nnc(C2CCN(C(=O)OC(C)(C)C)CC2)o1)Cc1cc(Cl)ccc1N>>CN1Cc2cc(Cl)ccc2-n2c(nnc2C2CCNCC2)C1,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US20010031870A1,C=CCN(C(=O)c1cc(Cl)cc(OCCCON2C(=O)c3ccccc3C2=O)c1)C1CCCC1>>C=CCN(C(=O)c1cc(Cl)cc(OCCCON)c1)C1CCCC1,,CCO,,CN,,test
US20050020830A1,CC(=O)OC1CC2CC1CN(Cc1ccccc1)C2>>OC1CC2CC1CN(Cc1ccccc1)C2,,CO,O,[K+].[OH-],,test
US20150299183A1,COc1c(-c2cn(COC(=O)C(C)(C)C)nn2)cccc1[N+](=O)[O-]>>COc1c(-c2c[nH]nn2)cccc1[N+](=O)[O-],,C1CCOC1,CO,Cl,[Na+].[OH-],test
US06211199B1,CC(C)(C)OC(=O)N1CCC(CCO)(c2ccccc2)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(CCOS(C)(=O)=O)(c2ccccc2)C1,,ClCCl,,CCN(CC)CC,,test
US20080167346A1,CC(C)N1CCC(N)CC1.CC(CNC(=O)OCc1ccccc1)S(=O)(=O)Cl>>CC(C)N1CCC(NS(=O)(=O)C(C)CNC(=O)OCc2ccccc2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20030045540A1,O=C(O)c1cc2ccoc2c(Cl)n1>>O=C(O)c1cc2c(cn1)OCC2,,CO,,,,test
US20150251969A1,CC(=O)O.CC(=O)c1cc(C2OCC(O)C2O)oc1C>>CCCCCCC(CC)CC,[Pd],CC(=O)O,,,,test
US06046331,COC(=O)C1(c2ccccc2)CCNCC1.COC(=O)c1[nH]c(=O)n(CCCCCBr)c1-c1ccc(F)c(F)c1>>COC(=O)c1[nH]c(=O)n(CCCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)c1-c1ccc(F)c(F)c1,,C1COCCO1,,[I-].[K+],O=C([O-])O.[Na+],test
US20120108583A1,Cn1c(Nc2c(Cl)cncc2Cl)nc2cc(C(=O)O)c3c(c21)CC(C)(C)O3.Nc1ccc(C(F)(F)F)c[n+]1[O-]>>Cn1c(Nc2c(Cl)cncc2Cl)nc2cc(C(=O)Nc3ccc(C(F)(F)F)cn3)c3c(c21)CC(C)(C)O3,[Fe],C1CCOC1,CC(=O)O,CCN(C(C)C)C(C)C,O=S(Cl)Cl,test
US20120077799A1,Nc1ncccc1C1(O)CCC(c2ccccc2)CC1>>Nc1ncccc1C1CCC(c2ccccc2)CC1,[Pd],CO,,O=C(O)C(F)(F)F,,test
US04347252,C#CCBr.CC(C)(C)C1CCNCC1>>C#CCN1CCC(C(C)(C)C)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090048230A1,BrCC1CC1.CC(C)C#N>>CC(C)(C#N)CC1CC1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20040110757A1,O=[N+]([O-])c1ccc(-c2cc(-c3ccc([N+](=O)[O-])cc3)nc(-c3ccccc3)n2)cc1>>Nc1ccc(-c2cc(-c3ccc(N)cc3)nc(-c3ccccc3)n2)cc1,[Pd],CC(=O)O,,,,test
US20090286807A1,COCCCOc1ccccc1N1CC(C)(C)N(C(=O)OC(C)(C)C)CC1=O>>COCCCOc1ccccc1N1CCN(C(=O)OC(C)(C)C)C(C)(C)C1,,C1CCOC1,,O,[Na+].[OH-],test
US20080214641A1,COc1cc(C(=O)[C@@H](C)NC(=O)OC(C)(C)C)ccc1SC>>COc1cc(C(O)[C@@H](C)NC(=O)OC(C)(C)C)ccc1SC,,C1CCOC1,,[BH4-].[Na+],,test
US20120101124A1,COc1ccc(C#N)c2ccoc12>>N#Cc1ccc(O)c2occc12,,ClCCl,,BrB(Br)Br,O,test
US20120088750A1,C=C(OCC)c1cc(OCc2ccccc2)cc2nc(NC(=O)NCC)sc12>>CCNC(=O)Nc1nc2cc(OCc3ccccc3)cc(C(C)=O)c2s1,,C1CCOC1,,Cl,,test
US20100063098A1,COC(=O)/C=C/C(=C/Nc1c(Cl)cccc1Cl)C(=O)OC>>COC(=O)c1ccc(=O)n(-c2c(Cl)cccc2Cl)c1,,CO,,Cl,C[O-].[Na+],test
US20090181963A1,CCn1nnc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(C(=O)O)cc4)cc3)nc21.NCCc1ccccn1>>CCn1nnc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(C(=O)NCCc5ccccn5)cc4)cc3)nc21,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130225620A1,CN.O=Cc1ccc2c(c1)ncn2C1CCCCO1>>CN=Cc1ccc2c(c1)ncn2C1CCCCO1,,CCO,CO,,,test
US20160083370A1,COc1cc(C)nc(N2CCNCC2)n1.Cc1ccc(S(=O)(=O)OCCCc2c[nH]c3ccc(C#N)cc23)cc1>>COc1cc(C)nc(N2CCN(CCCc3c[nH]c4ccc(C#N)cc34)CC2)n1,,CC#N,,[I-].[K+],,test
US03937704,COc1cc(N)c(C(=O)CS(C)=O)cc1OC.CS(C)=O>>Cc1ccc(N)c(C(=O)CS(C)=O)c1,,c1ccccc1,,[H-].[Na+],,test
US06184225B2,COc1cc2c(Oc3ccccc3)ncnc2cc1OCCN1CCOCC1>>COc1cc2c(=O)[nH]cnc2cc1OCCN1CCOCC1,,ClCCl,,Cl,O=C([O-])O.[Na+],test
US04221794,CC(CO)n1cnc2c(Cl)ncnc21.I>>CC(CO)n1cnc2c(I)ncnc21,,O,,,,test
US20070197512A1,COC(=O)CCN1C(=O)C(C(C)C)Oc2c1cccc2C(C)(C)C>>CC(C)C1Oc2c(cccc2C(C)(C)C)N(CCC(=O)O)C1=O,,CO,,[Na+].[OH-],,test
US20100227858A1,C[C@H]1COCCN1c1cc(C(C)(C)S(C)(=O)=O)nc(Cl)n1.OB(O)c1cnc2[nH]ccc2c1>>C[C@H]1COCCN1c1cc(C(C)(C)S(C)(=O)=O)nc(-c2cnc3[nH]ccc3c2)n1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20080090818A1,Brc1cccc2ccsc12.CCOC(=O)OCC>>CCOC(=O)c1cccc2ccsc12,,C1CCOC1,,[Mg],[Cl-].[NH4+],test
US20150315198A1,CC(C)(C)OC(=O)CBr.COc1ccc(C#N)c(O)c1>>COc1ccc(C#N)c(OCC(=O)OC(C)(C)C)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05340497,CCCCCCCCC(=O)Cl.CCCCCCCOc1ccc(-c2ncc(O)cn2)c(F)c1>>CCCCCCCCC(=O)Oc1cnc(-c2ccc(OCCCCCCC)cc2F)nc1,,Cc1ccccc1,,c1ccncc1,,test
US05891901,Cc1ccc2c(CC(=N)OC(C)C)cn(C)c2c1.Cn1cc(C(=O)C(=O)Cl)c2ccccc21>>Cc1ccc2c(C3=C(c4cn(C)c5ccccc45)C(=O)NC3=O)cn(C)c2c1,,ClCCl,,CCN(CC)CC,Cl,test
US06150373,CSc1ncc(CNc2ccccc2Br)c(Nc2cccc(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)c2)n1.O=C(Cl)Cl>>CSc1ncc2c(n1)N(c1cccc(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)c1)C(=O)N(c1ccccc1Br)C2,,CCOC(C)=O,Cc1ccccc1,CCN(CC)CC,O=C([O-])O.[Na+],test
US20020183307A1,CCCCC1(CCCC)CS(=O)(=O)c2ccc(N(C)C)cc2C(c2ccc(O)cc2)N1.ClCc1ccc(CCl)cc1>>CCCCC1(CCCC)CS(=O)(=O)c2ccc(N(C)C)cc2C(c2ccc(OCc3ccc(CCl)cc3)cc2)N1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05990105,Nc1ccc(S(=O)(=O)c2cc(Br)nc(N3CCCC3)c2)cc1>>Nc1ccc(S(=O)(=O)c2ccnc(N3CCCC3)c2)cc1,,C1CCOC1,CCCCCC,O,[Li]CCCC,test
US20100190764A1,CCOC(=O)C1CN(Cc2ccccc2)CCO1.O=C(O)C(F)(F)F>>CCOC(=O)C1CNCCO1.O=C(O)C(F)(F)F,[Pd],CCO,,,,test
US06143764,CCCN=C=O.COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC>>CCCNC(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1,,CN(C)C=O,,O,,test
US20110294806A1,CC(C)(C)OC(=O)N1CCC(n2cc(-c3cnc4ccn(NCc5ccccc5)c4c3)cn2)CC1>>c1ccc(CNn2ccc3ncc(-c4cnn(C5CCNCC5)c4)cc32)cc1,,CO,,Cl,,test
US20110251186A1,CC(C)(C)OC(=O)CC1(O)c2cc(Br)ccc2Oc2c1cc(Cl)nc2F>>OCCC1(O)c2cc(Br)ccc2Oc2c1cc(Cl)nc2F,,C1CCOC1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20140046069A1,O=C1NC(=O)c2ccccc21.OCc1cnc(N2CCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)nc1C(F)(F)F>>O=C1c2ccccc2C(=O)N1Cc1cnc(N2CCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)nc1C(F)(F)F,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020099055A1,CCOC(=O)c1cn(Cc2cccc3ccccc23)nc1C(=O)CC(C)C.CNN>>CC(C)Cc1nn(C)c(=O)c2cn(Cc3cccc4ccccc34)nc12,,CCO,,,,test
US20130324530A1,CC1(C)CC(C=O)CCO1.Nc1cnc(Cl)c(Br)c1>>CC1(C)CC(CNc2cnc(Cl)c(Br)c2)CCO1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090281075A1,C[C@@H](Nc1nc(NC[C@@H]2CCN(C(=O)OC(C)(C)C)C2)ncc1[N+](=O)[O-])c1cc(Cl)ccc1Cl>>C[C@@H](Nc1nc(NC[C@@H]2CCN(C(=O)OC(C)(C)C)C2)ncc1N)c1cc(Cl)ccc1Cl,[Pt],CO,,,,test
US04461902,CC1(C(=O)O)CC=CCC1>>CC12CCCC(C1)OC2=O,,ClC(Cl)Cl,,O=S(=O)(O)O,,test
US20080153850A1,ClCCl.O=C(O)C1CN(c2ncccc2Br)C1>>COC(=O)C1CN(c2ncccc2Br)C1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20080249180A1,CN(C)C(=O)C(C(=O)O)c1ccccc1.COc1ccc(NCCc2ccc(OC)c(OC)c2)cc1>>COc1ccc(N(CCc2ccc(OC)c(OC)c2)C(=O)C(C(=O)N(C)C)c2ccccc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20050113370A1,CC(C)(C)OC(=O)n1nc(-c2ccccc2)c2ccc(Nc3ccccc3F)cc21.Cl>>Cl.Fc1ccccc1Nc1ccc2c(-c3ccccc3)n[nH]c2c1,,CCOCC,CO,,,test
US20090233900A1,CCOC(=O)N1C(=O)c2ccccc2C1=O.Nc1cc2c(c(C(F)(F)F)c1)CC(=O)N2>>O=C1Cc2c(cc(N3C(=O)c4ccccc4C3=O)cc2C(F)(F)F)N1,,CN(C)C=O,,CCN(CC)CC,O,test
US04241071,CCC(=O)Cl.Cc1ccc(Cc2ccccc2C2(O)CCN(CCc3ccccc3)CC2)c(F)c1>>CCC(=O)OC1(c2ccccc2Cc2ccc(C)cc2F)CCN(CCc2ccccc2)CC1.Cl,,C1CCOC1,O,[Li]CCCC,,test
US20100022518A1,CC(C)(C)OC(=O)N1CCC(=O)N(CCCN2CCCCC2)CC1>>O=C1CCNCCN1CCCN1CCCCC1,,ClCCl,,CO,Cl,test
US20140170207A1,CC(Br)C(=O)Br.CCCCCCCCCCCCO>>CCCCCCCCCCCCOC(=O)C(C)Br,,Cc1ccccc1,,CCN(CC)CC,,test
US20100331341A1,CCOC(=O)Cc1cccc(OC)n1>>COc1cccc(CCO)n1,,CCO,,[BH4-].[Na+],,test
US20060063930A1,C=C(C)CCc1ccc(C(=O)O)cc1.NCCCCNC(=O)OCc1ccccc1>>CC(C)CCc1ccc(C(=O)NCCCCN)cc1,[Pd],,,Cl,,test
US04098911,Brc1ccc(Br)cc1.ClP(c1ccccc1)c1ccccc1>>Brc1ccc(P(c2ccccc2)c2ccccc2)cc1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20020058244A1,CN(C)C=O.ClOSCl.O=c1cc[nH][nH]1>>C[N+](C)=Cc1cn[nH]c1O.[Cl-],,CCO,,,,test
US20150232445A1,CC(=O)N1c2ccc(-c3cnn(C4CC4)c3)c(Oc3ncc4c(ncn4C4CCCCO4)n3)c2CC[C@@H]1C>>CC(=O)N1c2ccc(-c3cnn(C4CC4)c3)c(Oc3ncc4[nH]cnc4n3)c2CC[C@@H]1C,,CO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20080275043A1,O=C1C(Br)CCN1C1CCCCC1.Sc1ccc(Cl)cc1Cl>>O=C1C(Sc2ccc(Cl)cc2Cl)CCN1C1CCCCC1,,C1CCOC1,,[H-].[Na+],,test
US07071201B2,Brc1ccc2c(c1)NCC2.O=C1CCN(CCc2ccccc2F)CC1>>Fc1ccccc1CCN1CCC(N2CCc3ccc(Br)cc32)CC1,,CCOC(C)=O,ClCCCl,CC(=O)O,[Na+].[OH-],test
US20060223850A1,Brc1cncc(Br)c1.CSc1ccc(B(O)O)cc1>>CSc1ccc(-c2cncc(Br)c2)cc1,,CCOC(C)=O,,,,test
US20110294837A1,COc1ccc2c(Oc3ccc([N+](=O)[O-])cc3F)ccnc2c1>>COc1ccc2c(Oc3ccc(N)cc3F)ccnc2c1,[Fe],C1CCOC1,CO,Cl,,test
US20110144091A1,COC(CNC1=Nc2ccccc2CC[C@H]1NC(=O)OCc1ccccc1)OC>>O=C(N[C@@H]1CCc2ccccc2-n2ccnc21)OCc1ccccc1,,O=CO,,,,test
US06002008,CCOc1cc(N)c(C(=O)OC)cc1OCC.CN(C)C=O>>CCOc1cc(N=CN(C)C)c(C(=O)OC)cc1OCC,,ClCCl,,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US20130116235A1,Cn1cc(-c2ccnc(-n3ncc4c5c(sc4c3=O)CCCC5)c2C=O)cc(Nc2ccncn2)c1=O>>Cn1cc(-c2ccnc(-n3ncc4c5c(sc4c3=O)CCCC5)c2CO)cc(Nc2ccncn2)c1=O,,CO,,[BH4-].[Na+],,test
US20150257385A1,O=S(Cl)Cl.OCc1ccc(Oc2ccc(Cl)cc2)nc1>>ClCc1ccc(Oc2ccc(Cl)cc2)nc1,,ClCCl,,,,test
US20160016948A1,CC1(C)OB(c2cnn(S(=O)(=O)C3CC3)c2)OC1(C)C.Cc1nc2cnc(Nc3ccnc(Cl)n3)cc2n1C(C)C(F)(F)F>>Cc1nc2cnc(Nc3ccnc(-c4cnn(S(=O)(=O)C5CC5)c4)n3)cc2n1C(C)C(F)(F)F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20040186077A1,Cc1ncc(C(O)P(=O)(OC(C)(C)C)OC(C)(C)C)c(C)c1OCc1ccccc1>>Cc1ncc(C(O)P(=O)(O)O)c(C)c1OCc1ccccc1,,CC(=O)O,O,,,test
US20130039906A1,CCCCC[Sn](CCCC)(CCCCC)c1ccccn1.Ic1n[nH]c2cnc(-c3cccnc3)cc12>>c1ccc(-c2n[nH]c3cnc(-c4cccnc4)cc23)nc1,[Cu]I,C1COCCO1,,[Cl-].[Li+],,test
US20110112103A1,C=O.CC(=O)c1ccc(C(C)(C)C)cc1.CNC>>CN(C)CCC(=O)c1ccc(C(C)(C)C)cc1,,CCO,,Cl,Cl,test
US20110201593A1,CC[NH+]1CCC(O)(O)C(F)(F)C1.NO>>CCN1CCC(=NO)C(F)(F)C1,,CCO,,,,test
US20060234997A1,CCCC(Cl)Br.O=C1NCCc2ccc(O)cc2N1>>O=C1NCCc2ccc(OCCCCCl)cc2N1,,CCO,,O=C([O-])[O-].[Cs+].[Cs+],,test
US07491827B2,O=C(Nc1cccc2c(S(=O)(=O)O)cccc12)c1ccccc1.O=S(Cl)Cl>>O=C(Nc1cccc2c(S(=O)(=O)Cl)cccc12)c1ccccc1,,ClCCl,,,,test
US20040127527A1,CCOC(=O)CC(N)C(=O)c1ccc(Cl)s1.O=C(Cl)c1ccc(F)cc1>>CCOC(=O)CC(NC(=O)c1ccc(F)cc1)C(=O)c1ccc(Cl)s1,,CCOC(C)=O,O,Cl,O=C([O-])O.[Na+],test
US20050020605A1,CC1(N2CCC(C(Oc3ccccn3)c3ccc(Br)cc3)CC2)CCNCC1.O=C(O)c1cccc2ncccc12>>CC1(N2CCC(C(Oc3ccccn3)c3ccc(Br)cc3)CC2)CCN(C(=O)c2cccc3ncccc23)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090118305A1,CC(C)(C)OC(=O)OC(C)(C)C.CN(C)C=O.Nc1ncc(Br)cc1-c1nc2c(F)cccc2o1>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(Br)cc1-c1nc2c(F)cccc2o1,CN(C)c1ccncc1,CN(C)C=O,,,,test
US20070106095A1,CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc2ccc(OS(C)(=O)=O)cc2o1>>CCC(CC)(c1ccc(OCC(O)C(C)(C)C)c(C)c1)c1cc2ccc(OS(C)(=O)=O)cc2o1,,C1CCOC1,,[BH4-].[Na+],,test
US20110071152A1,CCOC(=O)C(C#N)=C(C)OCC.Cc1ccc(C(=O)O)cc1NN>>CCOC(=O)c1c(C)nn(-c2cc(C(=O)O)ccc2C)c1N,,CCO,,CCN(CC)CC,Cl,test
US20160145202A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.CNC(=O)OCc1cc(Br)ccc1Cl>>CNC(=O)OCc1cc(C(C)=O)ccc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20110160221A1,CC(C)(C)OC(=O)NCCN(Cc1ccc(Cl)cc1)C(=O)N1CCNCC1.C[C@@H]1CCc2ncnc(Cl)c21>>C[C@@H]1CCc2ncnc(N3CCN(C(=O)N(CCNC(=O)OC(C)(C)C)Cc4ccc(Cl)cc4)CC3)c21,,CC#N,O,CCN(C(C)C)C(C)C,,test
US20110166123A1,C1COCCN1.CCOC(=O)c1cn([C@@H](C(C)(C)C)C(C)(C)O[SiH2]C(C)(C)C)c2nc(F)c(Cc3cccc(Cl)c3F)cc2c1=O>>CC(C)(C)[C@@H](CO)n1cc(C(=O)O)c(=O)c2cc(Cc3cccc(Cl)c3F)c(N3CCOCC3)nc21,,CO,,[Na+].[OH-],,test
US09422320B2,COCOc1cc(OCc2ccccc2)ccc1/C=C\[N+](=O)[O-].Cc1ccccc1>>COCOc1cc(OCc2ccccc2)ccc1C1CC=CCC1[N+](=O)[O-],,Cc1ccccc1,,,,test
US20090076070A1,CC(Oc1ccc(-c2nc(-c3cccc4nccn34)no2)cc1C(F)(F)F)C(F)(F)F.O=C1CCC(=O)N1Cl>>CC(Oc1ccc(-c2nc(-c3cccc4ncc(Cl)n34)no2)cc1C(F)(F)F)C(F)(F)F,,CCO,,O,,test
US04692464,CCOCC.O=C(Cl)c1ccccc1.O=C([O-])O.O=C([O-])c1ccccc1.c1ccncc1>>O=C1C[C@H]2C[C@@H](OC(=O)c3ccccc3)[C@H](COCc3ccccc3)[C@H]2C1,,O,c1ccncc1,O=S(=O)(O)O,,test
US20140179666A1,CC[C@H]1CN(C(=O)OC(C)(C)C)[C@H](C)CN1CC(=O)OCc1ccccc1>>CC[C@H]1CN(C(=O)OC(C)(C)C)[C@H](C)CN1CC(=O)O,[Pd],CO,,,,test
US20120129870A1,O=S(Cl)Cl.OC(c1ccccc1)c1ccncc1>>ClC(c1ccccc1)c1ccncc1,,ClCCl,,[Na+].[OH-],,test
US20020198388A1,CCOC(=O)CNC(=O)NCCC(C)(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]1CO[C@@H]2OCC[C@H]12)S(=O)(=O)c1ccc(OC)cc1.CCOC(=O)CNC(=O)NCCC(C)(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc(OC)cc1.N>>COc1ccc(S(=O)(=O)NC(CC(C)(C)CCNC(=O)NCC(N)=O)[C@H](O)[C@H](Cc2ccccc2)NC(=O)O[C@@H]2CO[C@@H]3OCC[C@H]23)cc1,,CO,,,,test
US05053508,Cl.Clc1cncc(N2CCNCC2)n1.O=C1C2C3CS(=O)(=O)CC3C2C(=O)N1CCCCBr>>Cl.O=C1C2C3CS(=O)(=O)CC3C2C(=O)N1CCCCN1CCN(c2cncc(Cl)n2)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US20110281840A1,CN(C)CCn1c(CC(C)(C)C)nc2cc(S(=O)(=O)CC3CCNCC3)ccc21.O=C(O)c1cn[nH]c1>>CN(C)CCn1c(CC(C)(C)C)nc2cc(S(=O)(=O)CC3CCN(C(=O)c4cn[nH]c4)CC3)ccc21,,ClCCl,,CCN(CC)CC,,test
US20030087924A1,C=CC(=O)Cl.OCc1ccccc1>>C=CC(=O)OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20050119295A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.NCc1ccccc1.O=[N+]([O-])C=Cc1cccc(F)c1>>Fc1cccc(-c2cn(Cc3ccccc3)c3c2CNCC3)c1,,CCO,,,,test
US20090306405A1,COC(=O)/C=C/c1ccc(C=O)cc1.Cc1[nH]c2ccccc2c1CCN.Cl>>COC(=O)/C=C/c1ccc(CNCCc2c(C)[nH]c3ccccc23)cc1.Cl,,CO,O,[BH4-].[Na+],,test
US20160207926A1,CCCN.Nc1c(Cl)ncnc1Cl>>CCCNc1ncnc(Cl)c1N,,CC(C)O,O,,,test
US04218472,O=C1NC(=O)c2ccccc21.OC(CBr)C1=CC2(CCCC2)c2ccccc21>>NCC(O)C1=CC2(CCCC2)c2ccccc21,,CN(C)C=O,O,[K],,test
US06011034,CCOC(=O)N1CC(OCC)OC(c2cccc(C(F)(F)F)c2)=N1>>CCOC1CNN=C(c2cccc(C(F)(F)F)c2)O1,,O,,CCO,[K+].[OH-],test
US20110071150A1,CC1(C)OB(c2ccc3c(c2)cc(-c2c(F)cccc2F)n3S(=O)(=O)c2ccccc2)OC1(C)C.CCn1nc(-c2cnccn2)cc1OS(=O)(=O)C(F)(F)F>>CCn1nc(-c2cnccn2)cc1-c1ccc2c(c1)cc(-c1c(F)cccc1F)n2S(=O)(=O)c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US20030004340A1,CC1CNCCC1(C)c1cccc(-c2c[nH]nn2)c1.CN(C)C=O.COCCCCI>>COCCCCN1CCC(C)(c2cccc(-c3c[nH]nn3)c2)C(C)C1.N,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US04604389,COc1cc2c(cc1OC)CC(=O)N(CCCN(C)CCCSc1cc(Br)c(N)c(Br)c1)CC2.OO>>COc1cc2c(cc1OC)CC(=O)N(CCCN(C)CCCS(=O)c1cc(Br)c(N)c(Br)c1)CC2,,CC(=O)O,,,,test
US20130029961A1,COCCN(C)c1ccc(C(C)C(=O)OC)cn1>>COC(=O)C(C)c1ccc(N(C)CCO)nc1,,ClCCl,O,BrB(Br)Br,O=C([O-])O.[Na+],test
US20070167436A1,CC(C)O.O=C(C1CCC(Nc2ccc(O)nc2)CC1)N1CCN(C2CCC2)CC1>>CC(C)Oc1ccc(NC2CCC(C(=O)N3CCN(C4CCC4)CC3)CC2)cn1,,C1CCOC1,,,,test
US05756504,COc1cc(OC2CCNCC2)ccc1CC(=O)N1CCN(c2ccccc2C)CC1C(N)=O.ClCc1ccccn1>>COc1cc(OC2CCN(Cc3cccnc3)CC2)ccc1CC(=O)N1CCN(c2ccccc2C)CC1C(N)=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20020072528A1,CC(C)CNc1c(N)cnc2ccccc12.S=C=S>>Sc1nc2cnc3ccccc3c2s1,,[Na+],[OH-],CCO,,test
US20150038574A1,C[C@H]1CCCC(C)(C)[C@@H]1CO.Oc1ccc(F)c(F)c1>>C[C@H]1CCCC(C)(C)[C@@H]1COc1ccc(F)c(F)c1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05969146,COC(=O)CS.COc1ccc(C#N)c([N+](=O)[O-])c1>>COC(=O)c1sc2cc(OC)ccc2c1N,,O,,[K+].[OH-],,test
US20150232435A1,CC(C)(C)c1nc(N2CCN(CCCCNC(=O)c3cn4c(CO)cccc4n3)CC2)cc(C(F)(F)F)n1.CNC>>CN(C)Cc1cccc2nc(C(=O)NCCCCN3CCN(c4cc(C(F)(F)F)nc(C(C)(C)C)n4)CC3)cn12,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20050277638A1,O=c1n(-c2ccc(Oc3ccccc3)cc2)ccn1-c1ccc2c(cnn2CCN2CCCC2)c1>>O=C1N(c2ccc(Oc3ccccc3)cc2)CCN1c1ccc2c(cnn2CCN2CCCC2)c1,[Pd],CC(=O)O,,[H][H],,test
US20050250811A1,CC(=O)OC1CN(C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)CCC1Br>>CC(=O)OC1C=CCN(C(=O)[C@H](NC(=O)OC(C)(C)C)C(C)C)C1,,Cc1ccccc1,,C1CCC2=NCCCN2CC1,,test
US20030087926A1,C=Cc1cccc(F)c1.CCC(=O)C(=O)[O-].Nc1cc(Cl)cc(Cl)c1>>CCOC(=O)C1CC(c2cccc(F)c2)c2c(Cl)cc(Cl)cc2N1,,CC#N,,O=C(O)C(F)(F)F,,test
US04602002,NC(CCC(O)CNC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O.O=C(O)C(=O)CCc1ccccc1>>O=C(NCC(O)CCC(NC(CCc1ccccc1)C(=O)O)C(=O)N1CCC[C@H]1C(=O)O)OCc1ccccc1,,CCO,O,[Na+].[OH-],,test
US20150141650A1,COC(=O)C12CC3CC(C1)N(C(=O)OC(C)(C)C)C(C3)C2>>CC(C)(C)OC(=O)N1C2CC3CC1CC(CO)(C3)C2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070072920A1,CCOC(=O)C=Cc1cc(OC)c(C[C@@H](C)NC(=O)C(F)(F)F)cc1OC>>CCOC(=O)CCc1cc(OC)c(C[C@@H](C)NC(=O)C(F)(F)F)cc1OC,[Pd],CCO,,,,test
US05703109,N#Cc1ccc(C(Cl)CCc2ccc(F)cc2)cc1.c1nnn[nH]1>>N#Cc1ccc(C(CCc2ccc(F)cc2)n2ncnn2)cc1,,O,,CN(C)C=O,[H-].[Na+],test
US20070105902A1,CCCS(=O)(=O)N1CCC(c2ccccc2)([C@H](C)N)CC1.O=C(Cl)c1ccccc1OC(F)(F)F>>CCCS(=O)(=O)N1CCC(c2ccccc2)([C@H](C)NC(=O)c2ccccc2OC(F)(F)F)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04933355,CCNc1nc(C(=O)OCC)cs1>>CCNc1nc(CO)cs1,,C1CCOC1,,CO,[BH4-].[Na+],test
US20050203184A1,CCCCC[C@H](C=Cc1ccccc1C=C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](CCCC(=O)OC)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C>>CCCCC[C@@H](O)C=Cc1ccccc1C=C[C@@H](O)[C@@H](O)CCCC(=O)OC,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110053925A1,CC(C)(C)OC(=O)N1CC=CC(=O)C1.Cc1cc2ccccc2[nH]1>>Cc1[nH]c2ccccc2c1C1CC(=O)CN(C(=O)OC(C)(C)C)C1,,ClCCl,,II,,test
US20130196974A1,Cc1ccc2nc(Cl)nc(Cl)c2c1.NCC1(CN)COC1>>Cc1ccc2nc(Cl)nc(NCC3(CN)COC3)c2c1,,ClCCl,O,CCN(CC)CC,,test
US20060264429A1,CO.Cc1ccc2c(N3CCN(CC(O)c4ccc5c(c4)NC(=O)CO5)CC3)cccc2n1>>COC(CN1CCN(c2cccc3nc(C)ccc23)CC1)c1ccc2c(c1)NC(=O)CO2,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20130172342A1,BrC(Br)(Br)Br.Cc1cccc(C)c1CCCO>>Cc1cccc(C)c1CCCBr,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100130359A1,CCC(O)N(C)C.Cc1nnc(Cl)c(-c2c(F)cc(O)cc2F)c1-c1ccc(Cl)cc1>>Cc1nnc(Cl)c(-c2c(F)cc(OCCCN(C)C)cc2F)c1-c1ccc(Cl)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060241172A1,COc1c(C=O)cc(F)cc1-c1c(Cl)cccc1Cl.O=C(OO)c1cccc(Cl)c1>>COc1c(O)cc(F)cc1-c1c(Cl)cccc1Cl,,CO,ClCCl,Cl,[Na+].[OH-],test
US20070254046A1,CC(C)(C)OC(=O)Nc1ccc(Nc2nc(-c3ccc4cc(OCc5ccccc5)ccc4c3)cc3ccnn23)cc1>>Nc1ccc(Nc2nc(-c3ccc4cc(OCc5ccccc5)ccc4c3)cc3ccnn23)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150368246A1,CNC(=O)c1c(-c2ccc(F)cc2F)oc2cc(N(C)S(C)(=O)=O)c(B3OC(C)(C)C(C)(C)O3)cc12.Fc1cccc2c1cc1c3nc(Cl)ccc3ncn21>>CNC(=O)c1c(-c2ccc(F)cc2F)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4ncn5c6cccc(F)c6cc5c4n3)cc12,O,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050176751A1,COCCn1cc(C2CCN(Cc3cccc(C(=O)OC)c3)CC2)c2cccnc21>>COCCn1cc(C2CCN(Cc3cccc(C(=O)O)c3)CC2)c2cccnc21,,CCO,,[Na+].[OH-],,test
US20160052884A1,COC(=O)c1ccc(NC(=O)C(C(C)C)n2cc(OC)c(-c3cc(Cl)ccc3C#N)cc2=O)cc1C>>COc1cn(C(C(=O)Nc2ccc(C(=O)O)c(C)c2)C(C)C)c(=O)cc1-c1cc(Cl)ccc1C#N,,CO,,[Na+].[OH-],,test
US04589905,CCNC.N#Cc1cccc(-n2ncc(C(=O)O)c2C#N)c1>>CCN(C)C(=O)c1cnn(-c2cccc(C#N)c2)c1C#N,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20140031364A1,COC(=O)CC#N.ON=C(Cl)c1ccc(OC(F)(F)F)cc1>>COC(=O)c1c(-c2ccc(OC(F)(F)F)cc2)noc1N,,CO,,C[O-].[Na+],,test
US20110076292A1,CC(C)n1cncn1.FC(F)(Cl)C(F)(Cl)Cl>>CC(C)n1ncnc1Cl,,C1CCOC1,,[Li]CCCC,,test
US20060247250A1,CC(=O)Oc1cccc(C(=O)Cl)c1C.CN1CCN(C(=O)c2ccc(Nc3ncc(NC(=O)c4c(Cl)cccc4Cl)cn3)cc2)CC1>>CC(=O)Oc1cccc(C(=O)Nc2cnc(Nc3ccc(C(=O)N4CCN(C)CC4)cc3)nc2)c1C,,C1CCOC1,,,,test
US20020123497A1,CC(C)(C)OC(=O)N1CCN(Cc2cc(OS(C)(=O)=O)ccc2Cl)C(=O)C1>>CC(C)(C)OC(=O)N1CCN(Cc2cc(O)ccc2Cl)C(=O)C1,,CCO,O,CC(C)(C)[O-].[K+],,test
US04923857,CC(C)(C)[Si](C)(C)Cl.OCC1CCC(CO)N1Cc1ccccc1>>CC(C)(C)[Si](C)(C)OCC1CCC(CO)N1Cc1ccccc1,,CCOC(C)=O,CN(C)C=O,O,c1c[nH]cn1,test
US06281363B1,CC(C)C[C@@H](C(=O)NN1C(=O)C2CNCCN2C1=O)[C@H](C/C=C/c1ccccc1)C(=O)O.NOCc1ccccc1>>CC(C)C[C@@H](C(=O)NN1C(=O)C2CNCCN2C1=O)[C@H](C/C=C/c1ccccc1)C(=O)NOCc1ccccc1,,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,Cl,test
US20110144106A1,CC1(C)C[C@]12C(=O)Nc1ccc(F)cc12.COC(=O)c1cc(Br)cc(N2CCOC2=O)c1>>COC(=O)c1cc(N2CCOC2=O)cc(N2C(=O)[C@]3(CC3(C)C)c3cc(F)ccc32)c1,[Cu]I,CC#N,,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US20120035237A1,Clc1ccccc1CBr.O=C(Nc1c(F)cccc1F)c1ccn(Cc2cc(Cl)ccc2O)n1>>O=C(Nc1c(F)cccc1F)c1ccn(Cc2cc(Cl)ccc2OCc2ccccc2Cl)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080058328A1,CN.Clc1ccc(CBr)c(Br)c1>>NCCc1ccc(Cl)cc1Br,,CCO,,,,test
US20120252789A1,CC1(C)CCC(C)(C)c2cc(-c3cccc(N4CCC(=O)CC4)n3)ccc21.CC1(C)O[C@@H]2CCC[C@@H](N)[C@@H]2O1>>CC1(C)O[C@@H]2CCC[C@@H](NC3CCN(c4cccc(-c5ccc6c(c5)C(C)(C)CCC6(C)C)n4)CC3)[C@@H]2O1,,C1CCOC1,,,,test
US20130336920A1,COCCN(CCNC(=O)OCc1ccccc1)CCOCCOCCOCCNC(=O)OC(C)(C)C>>CNCCN(C)CCOCCOCCOCCNC(=O)OC(C)(C)C,[Pd],CO,,,,test
US04619931,CNCC(OC)OC.COc1ccc(N2CCN(c3ccc(N=C=S)cc3)CC2)cc1>>COc1ccc(N2CCN(c3ccc(NC(=S)N(C)CC(OC)OC)cc3)CC2)cc1,,ClCCl,,,,test
US04378357,CC(C)(O)C#N.CC(O)CC(C)(C)O>>CC1CC(C)(C)N=C(C(C)(C)O)O1,,O=S(=O)(O)O,,,,test
US20150232481A1,C[C@H](CCCCOC1(C)CCN(C(=O)OC(C)(C)C)CC1)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>C[C@H](CCCCOC1(C)CCNCC1)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,C1COCCO1,,Cl,,test
US20020022002A1,CC(=O)c1ccc2cc(O)ccc2c1.CNCCO>>CC(=O)c1ccc2cc(N(C)CCO)ccc2c1,,CCOC(C)=O,O,O=S([O-])O.[Na+],,test
US20130005707A1,C1=COCCC1.O=[N+]([O-])c1ccc2cn[nH]c2c1>>O=[N+]([O-])c1ccc2cnn(C3CCCCO3)c2c1,,C1CCOC1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US06177440B1,COC(=O)CBr.NC(=O)c1cccc2c1c1c(O)cccc1n2Cc1cccc(OC(F)(F)F)c1>>COC(=O)COc1cccc2c1c1c(C(N)=O)cccc1n2Cc1cccc(OC(F)(F)F)c1,,CCOC(C)=O,CN(C)C=O,,,test
US20100261679A1,CNC(=O)c1cc(Oc2ccc3nc(S(C)=O)ncc3c2)ccn1.N[C@@H]1CCCC[C@H]1O>>CNC(=O)c1cc(Oc2ccc3nc(N[C@@H]4CCCC[C@H]4O)ncc3c2)ccn1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,Cl,test
US05886044,O=C=O.c1ccc2c(c1)OCO2>>O=C(O)c1cccc2c1OCO2,,CCCCCC,CCOCC,[Li]CCCC,O=C([O-])O.[Na+],test
US20080090834A1,N#Cc1ccc(Br)cc1.Nc1cncnc1>>NC(=Nc1cncnc1)c1ccc(Br)cc1,,CS(C)=O,,[H-].[Na+],,test
US20020099215A1,O=C(NC(CCCc1ccccc1)CCCc1ccccc1)C1CCCN(C(=O)C2CCCNC2)C1.c1cc(OC[C@H]2CO2)c2cccnc2c1>>O=C(NC(CCCc1ccccc1)CCCc1ccccc1)C1CCCN(C(=O)C2CCCN(C[C@@H](O)COc3cccc4ncccc34)C2)C1,,CCO,,,,test
US06627651B1,CCCOCc1ccc(COc2ccc3c(c2)C=C(C(=O)OC)CCS3(=O)=O)cc1>>CCCOCc1ccc(COc2ccc3c(c2)C=C(C(=O)O)CCS3(=O)=O)cc1,,C1CCOC1,CO,O=C([O-])[O-].[K+].[K+],,test
US04322417,CC1CO1.Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1S>>CC1CSc2cc(C(O)(C(F)(F)F)C(F)(F)F)ccc2N1,,CCO,,C,C[O-].[Na+],test
US20110183947A1,COC(=O)c1cccc(-c2nnc(CC(O)Cc3ccc(-c4ccccc4)cc3)o2)n1>>COC(=O)c1cccc(-c2nnc(CC(=O)Cc3ccc(-c4ccccc4)cc3)o2)n1,,CO,ClCCl,,,test
US04720495,CCOC(=O)c1cn2c3c(c(Cl)c(Cl)cc3c1=O)C(=O)CC2C>>CC1CC(=O)c2c(Cl)c(Cl)cc3c(=O)c(C(=O)O)cn1c23,,CC(=O)O,Cl,,,test
US06673850B1,C=C(CBr)C(=O)OC.CC(C)(C(=O)c1ccc(SCCCS)cc1)N1CCOCC1>>C=C(CSCCCSc1ccc(C(=O)C(C)(C)N2CCOCC2)cc1)C(=O)OC,,CO,,O,O=C([O-])[O-].[K+].[K+],test
US20020120007A1,CCCc1ccc(C(=O)Cl)cc1.COc1ccc(C(=O)Nc2ccc(O[Si](C)(C)C(C)(C)C)cc2N)cc1>>CCCc1ccc(C(=O)Nc2cc(O[Si](C)(C)C(C)(C)C)ccc2NC(=O)c2ccc(OC)cc2)cc1,,ClCCl,,c1ccncc1,,test
US20100093757A1,CC(C)(C)OC(=O)NN(C(=O)OC(C)(C)C)c1c(Cl)cccc1Br.Cl>>Cl.NNc1c(Cl)cccc1Br,,CC(C)O,,C1COCCO1,,test
US20100240702A1,CCOC(=O)CCNc1cc(C(=O)OC(C)(C)C)ccc1N.O=C(n1ccnc1)n1ccnc1>>CCOC(=O)CCn1c(=O)[nH]c2ccc(C(=O)OC(C)(C)C)cc21,,C1CCOC1,,,,test
US20080021043A1,COC(=O)OC.Cc1ccnc(Cl)c1>>COC(=O)Cc1ccnc(Cl)c1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US05753664,CC(C)I.Cn1c(=O)[nH]c(=O)c2c1ncn2Cc1ccc(C(=O)c2ccc(Cl)cc2)cc1>>CC(C)n1c(=O)c2c(ncn2Cc2ccc(C(=O)c3ccc(Cl)cc3)cc2)n(C)c1=O,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20160235775A1,O=C1c2cc(Br)ccc2-c2ccc(Br)cc21.SCCCS>>Brc1ccc2c(c1)C1(SCCCS1)c1cc(Br)ccc1-2,,ClCCl,,CCOCC,FB(F)F,test
US20090143361A1,COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)cc(Cl)c4)n3c2n1.OB(O)c1cc(Cl)ccc1Cl>>COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)ccc4Cl)n3c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20150183741A1,COC(=O)c1cccc2cc(O[C@@H]3CC[C@H](C)CC3)ccc12.O=C1CCC(=O)N1I>>COC(=O)c1cccc2c(I)c(O[C@@H]3CC[C@H](C)CC3)ccc12,,CC#N,,O=C(O)C(F)(F)F,,test
US20150031674A1,CSc1ncc(CO)c(NCCC2OCC(NC(=O)OCc3ccccc3)CO2)n1>>CSc1ncc(C=O)c(NCCC2OCC(NC(=O)OCc3ccccc3)CO2)n1,O=[Mn]=O,ClCCl,,,,test
US20100240898A1,Brc1cccc2ccccc12.c1ccc(P(c2ccccc2)c2cccc3cccnc23)cc1>>C1=CC(c2cccc3ccccc23)Nc2c1cccc2P(c1ccccc1)c1ccccc1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20060052374A1,NO.O=Cc1cc(F)ccc1O>>ON=Cc1cc(F)ccc1O,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20040220193A1,C=CC#N.NC1CCN(Cc2ccccc2)C1>>N#CCCNC1CCN(Cc2ccccc2)C1,,CO,,,,test
US04794188,CC(=O)OC(C)=O.CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1>>CCCCCC(OC(C)=O)c1cccc(OCc2ccc3ccccc3n2)c1,,c1ccncc1,,,,test
US20100173944A1,CCCCCCCCCO.Cc1c(Cl)cc[n+]([O-])c1C>>CCCCCCCCCOc1cc[n+]([O-])c(C)c1C,,Cc1ccccc1,O,Cl,[Na+].[OH-],test
US05356905,CC(C)[Si](Oc1ccc2c(c1)OCC(Br)(Br)C2=O)(C(C)C)C(C)C.OC1(c2ccccc2)CCNCC1>>CC(C)[Si](Oc1ccc2c(=O)c(N3CCC(O)(c4ccccc4)CC3)coc2c1)(C(C)C)C(C)C,,CC#N,,CCN(CC)CC,,test
US20110251169A1,CC1(C)CCN(c2cnc(C#Cc3ccccc3)cn2)C(=O)N1.CI>>CN1C(=O)N(c2cnc(C#Cc3ccccc3)cn2)CCC1(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20100152175A1,Cc1cc(F)ccc1-c1cc(Cl)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.OC[C@H]1CN2CCNCC2CN1>>Cc1cc(F)ccc1-c1cc(N2CCN3C[C@H](CO)NCC3C2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110092512A1,FC1(F)Oc2ccc(Br)cc2O1.O=C1NCCC12CCC1(CC2)OCCO1>>O=C1N(c2ccc3c(c2)OC(F)(F)O3)CCC12CCC1(CC2)OCCO1,,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20120252805A1,CCOC(=O)c1c(C)nc2scc(-c3cccc(OC)c3)c2c1N.O=C1CCC(=O)N1Br>>CCOC(=O)c1c(C)nc2sc(Br)c(-c3cccc(OC)c3)c2c1N,,ClCCl,,,,test
US20070049587A1,COC(=O)[C@H]1CC(N=[N+]=[N-])[C@@H](OCCOC2CCCCO2)C1.O=C(O)c1ccc(Cl)s1>>COC(=O)C1C[C@H](NC(=O)c2ccc(Cl)s2)[C@@H](OCCOC2CCCCO2)C1,O=[Pt]=O,,,,,test
US20030045552A1,Nc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C(Cl)c1ccc(Cl)cc1>>O=C1CCC(N2C(=O)c3cccc(NC(=O)c4ccc(Cl)cc4)c3C2=O)C(=O)N1,,C1CCOC1,,CO,,test
US20060199851A1,CC(C)C=O.O=C(N[C@H](CNC[C@H](Cc1ccccc1)NC(=O)OCc1cncs1)Cc1ccccc1)OCc1cncs1>>CC(C)CN(C[C@H](Cc1ccccc1)NC(=O)OCc1cncs1)C[C@H](Cc1ccccc1)NC(=O)OCc1cncs1,,ClCCCl,,CC(=O)O,O=C([O-])O.[Na+],test
US20040082571A1,FC(F)(F)c1cc(C(F)(F)F)[nH]n1.O=C(CCl)N1CCN(c2ccc(F)cc2)CC1>>O=C(Cn1nc(C(F)(F)F)cc1C(F)(F)F)N1CCN(c2ccc(F)cc2)CC1,,CCCCCC,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05206235,Cc1ccc(S(=O)(=O)Cl)cc1.OCCc1cccc(C(F)(F)F)c1>>Cc1ccc(S(=O)(=O)OCCc2cccc(C(F)(F)F)c2)cc1,,CCOCC,,CCN(CC)CC,,test
US20130245254A1,CC(C)(O)c1ccc([Sn](C)(C)C)cn1.CO[C@@H]1CC[C@@H](N2C(=O)CNc3ncc(Br)nc32)CC1>>CO[C@@H]1CC[C@@H](N2C(=O)CNc3ncc(-c4ccc(C(C)(C)O)nc4)nc32)CC1,,CN(C)C=O,,,,test
US20090029976A1,CC(C)[Mg]Cl.COc1cc(O)c(C=O)cc1C>>COc1cc(O)c(C(O)C(C)C)cc1C,,C1CCOC1,,,,test
US20080176829A1,CC(=O)Cl.NCCOc1ccc2c(ccn2S(=O)(=O)c2ccccc2)c1>>CC(=O)NCCOc1ccc2c(ccn2S(=O)(=O)c2ccccc2)c1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US08987314B2,CCOC(=O)Cc1nc2ccc(Br)cc2s1.OB(O)c1ccnc(F)c1>>CCOC(=O)Cc1nc2ccc(-c3ccnc(F)c3)cc2s1,[Pd],C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20130296377A1,Cc1ccc(S(=O)(=O)n2ccc3c(COC4CCCCO4)c(C(O)CO)cc(C)c32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(COC4CCCCO4)c(C=O)cc(C)c32)cc1,,C1CCOC1,CCOC(C)=O,O,,test
US20090318501A1,CC(C)(C)OC(=O)N1CCC[C@@H]([C@@H](OCCN)c2cc(F)cc(Cl)c2)C1.CCOC(=O)Cl>>CCOC(=O)NCCO[C@@H](c1cc(F)cc(Cl)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1,,CCN(CC)CC,ClCCl,O,,test
US20110183954A1,COC1CNC1.C[C@H](Nc1nc(Cl)nc(Nc2cn(C)cn2)n1)c1ncc(F)cc1F>>COC1CN(c2nc(Nc3cn(C)cn3)nc(N[C@@H](C)c3ncc(F)cc3F)n2)C1,,CCO,,CCN(C(C)C)C(C)C,,test
US20070232645A1,Cc1cc(S)c(C)o1.Cc1ccc(Cl)c([N+](=O)[O-])c1>>Cc1ccc(Sc2cc(C)oc2C)c([N+](=O)[O-])c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100076027A1,COC(c1ccc(C#N)cc1F)(c1c2cc(F)c(F)cc2nn1-c1ccc(Cl)cc1)C1CCCCC1.[N-]=[N+]=[N-]>>Fc1cc2nn(-c3ccc(Cl)cc3)c(C(OCc3ccc(-c4nn[nH]n4)cc3F)C3CCCCC3)c2cc1F,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20040204409A1,CS(=O)(=O)Cl.OCc1ccc2oc(Cc3ccccc3)nc2c1>>CS(=O)(=O)OCc1ccc2oc(Cc3ccccc3)nc2c1,,ClCCl,,CCN(CC)CC,[Na+].[OH-],test
US20130005716A1,O=C(O)c1cccc(S(=O)(=O)Cl)c1>>O=S(=O)(Cl)c1cccc(CO)c1,,C1CCOC1,,,,test
US20160039804A1,O=Cc1nccnc1Cl>>OCc1nccnc1Cl,,CO,,[BH4-].[Na+],,test
US20110015240A1,CC(=O)Nc1nc(CCc2cc(C)c(C=O)s2)cs1.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)/C=C/c1sc(CCc2csc(NC(C)=O)n2)cc1C,,ClC(Cl)Cl,,,,test
US04738972,O=CCc1ccccc1.c1ccc2c(c1)CCCN2>>c1ccc(CCN2CCCc3ccccc32)cc1,,CC(=O)O,CO,Cl,[BH3-]C#N.[Na+],test
US20140271543A1,Brc1nnc[nH]1.O=c1[nH]cccc1Nc1ncc(F)c(N[C@@H]2CCCNC2)n1>>O=c1[nH]cccc1Nc1ncc(F)c(N[C@@H]2CCCN(c3nnc[nH]3)C2)n1,,CO,,CCOCC,,test
US20080280910A1,NN.O=C1OC(=Cc2ccc(F)c(Br)c2)c2cccc([N+](=O)[O-])c21>>O=c1[nH]nc(Cc2ccc(F)c(Br)c2)c2cccc([N+](=O)[O-])c12,,O,,,,test
US20160016903A1,CCOC(=O)CP(=O)(OCC)OCC.O=C1CCC(c2cccs2)(N2CCC2)CC1>>CCOC(=O)C=C1CCC(c2cccs2)(N2CCC2)CC1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20060047126A1,CC(=O)OC(C)=O.COC(=O)Cc1ccc(C(F)(F)F)cc1[N+](=O)[O-]>>COC(=O)Cc1ccc(C(F)(F)F)cc1NC(C)=O,[Pd],Cc1ccccc1,,,,test
US07648990B2,CC1CCC(C(C)C)C(OC(=O)Cl)C1.COc1ccncc1.Cc1cc(F)ccc1[Mg]Br>>Cc1cc(F)ccc1[C@H]1CC(=O)C=CN1C(=O)O[C@@H]1C[C@H](C)CC[C@H]1C(C)C,,C1CCOC1,,,,test
US20060229254A1,CCOC(=O)[C@@H]1CC[C@H](C)N1.O=C(Cl)CCCc1ccccc1>>CCOC(=O)[C@@H]1CC[C@H](C)N1C(=O)CCCc1ccccc1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US05112853,C=C(C(=O)OC)C1CCCCC1>>C=C(CO)C1CCCCC1,,CCOCC,,CC(C)C[Al+]CC(C)C.[H-],,test
US20130096121A1,CC(C)(C)OC(=O)c1nc(N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)ccc1Br.CC1(C)OB(c2cnn(Cc3ccccc3)c2)OC1(C)C>>CC(C)(C)OC(=O)c1nc(N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)ccc1-c1cnn(Cc2ccccc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,COCCOC,[Cs+].[F-],,test
US20060079533A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCCC1CNCC(O)C1c1ccc(Cl)cc1>>CCCC1CN(C(=O)OC(C)(C)C)CC(O)C1c1ccc(Cl)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20040209901A1,Cc1cc(F)ccc1-c1nc(S(C)(=O)=O)nc2c1ccc(=O)n2-c1c(F)cccc1F.NC1CCOCC1>>Cc1cc(F)ccc1-c1nc(NC2CCOCC2)nc2c1ccc(=O)n2-c1c(F)cccc1F,,C1CCOC1,,,,test
US20080319188A1,Nc1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ccn1.O=C(Cl)Oc1ccccc1.OCC1CNC1>>O=C(Nc1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ccn1)N1CC(CO)C1,,C1CCOC1,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20080090822A1,CC(O)c1ccc(N2CCN(C(=O)c3cc(S(C)(=O)=O)ccc3N3CCCCC3)CC2)c(F)c1.CI>>COC(C)c1ccc(N2CCN(C(=O)c3cc(S(C)(=O)=O)ccc3N3CCCCC3)CC2)c(F)c1,,CN(C)C=O,,[H-].[Na+],,test
US06166006,Cc1ccc(-c2cccc(/C=C/C(=O)Nc3ccc(CCl)cc3)c2)cc1.c1c[nH]cn1>>Cc1ccc(-c2cccc(/C=C/C(=O)Nc3ccc(Cn4ccnc4)cc3)c2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160194302A1,CCC(C)O.CN(C)C1CCN(C(=O)CCc2nccn2CC(=O)O)CC1>>CCC(C)OC(=O)Cn1ccnc1CCC(=O)N1CCC(N(C)C)CC1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06762180B1,CCCCO.O=C1Nc2cc(C(=O)O)ccc2/C1=C(/Nc1ccc(CN2CCCCC2)cc1)c1ccccc1>>CCCCOC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(CN2CCCCC2)cc1)c1ccccc1,,CCCCO,,,,test
US20030232809A1,CCOC(=O)Cc1c(-c2ccccc2)c2cc(C)c(Cl)cc2oc1=O.O=C1CCC(=O)N1Br>>O=C(O)Cc1c(-c2ccccc2)c2cc(CBr)c(Cl)cc2oc1=O,,CC(=O)O,CCOC(C)=O,Cl,,test
US20080194538A1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.Cc1ccc(S(=O)(=O)Oc2nc(N)nc3c2CCCc2ccccc2-3)cc1>>CC(C)(C)OC(=O)N[C@@H]1CCN(c2nc(N)nc3c2CCCc2ccccc2-3)C1,,CC#N,CCOC(C)=O,CCN(CC)CC,,test
US09315503B2,CC(C)[Si](OCCCN1CCC[C@H]1c1nnc2ccc(O[C@@H]3CC[C@H](N)c4ccccc43)cn12)(C(C)C)C(C)C.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc([C@@H]5CCCN5CCCO)n4c3)c3ccccc32)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20070072002A1,Cc1ccc(-c2c3ccccc3cc3ccccc23)cc1.O=C1CCC(=O)N1Br>>Cc1ccc(-c2c3ccccc3c(Br)c3ccccc23)cc1,,C1CCOC1,,O,,test
US06316494B1,c1ccc(COc2ccc3c(c2)OC[C@@H](c2ccccc2)[C@H]3c2ccc(OCCN3CCOCC3)cc2)cc1>>Oc1ccc2c(c1)OC[C@@H](c1ccccc1)[C@H]2c1ccc(OCCN2CCOCC2)cc1,[Pd],CCO,Cl,,,test
US05187286,CCCCBr.Cc1ccccc1CO>>CCCCCc1ccccc1CO,,CCCCCC,CCOCC,O,[Li]CCCC,test
US06090813,Clc1cc(N2CCN(Cc3ccccc3)CC2)ncn1>>c1cc(N2CCNCC2)ncn1,[Pd],CO,,,,test
US20120309754A1,Cc1nc2ccc(F)cc2nc1C(=O)CC#N.NN>>Cc1nc2ccc(F)cc2nc1-c1cc(N)[nH]n1,,CC(=O)O,CCO,O,,test
US20040006119A1,CC(=O)OC(C)=O.COC(=O)c1sccc1N>>COC(=O)c1sccc1NC(C)=O,,Cc1ccccc1,,,,test
US06420403B1,COc1cc(N)ccc1-c1cnco1.N#CN=C(Oc1ccccc1)Oc1ccccc1>>COc1cc(N=C(NC#N)Oc2ccccc2)ccc1-c1cnco1,,CC#N,,,,test
US06413974B1,Clc1nc(Cl)c2ncn(C3CCCC3)c2n1.NCCCCCO>>OCCCCCNc1nc(Cl)nc2c1ncn2C1CCCC1,,CCN(CC)CC,,,,test
US20090062294A1,CC(C)(C)OC(=O)N1CCC(=Cc2ccc3ccccc3c2)CC1>>CC(C)(C)OC(=O)N1CCC(Cc2ccc3ccccc3c2)CC1,[Pd],CCO,,,,test
US20030176415A1,COC(=O)CC1(C2CCc3cc(OC)c(OC)cc3C2Cc2ccc(OC)c(OC)c2)C=CC=CC1>>COc1ccc(CC2c3cc(OC)c(OC)cc3CCC2C2(CC(=O)O)C=CC=CC2)cc1OC,,C1COCCO1,CO,[Na+].[OH-],,test
US20140315895A1,C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(C(CC)C(=O)OC)C1=O>>C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(C(CC)C(=O)O)C1=O,,C1CCOC1,O,[Na+].[OH-],,test
US20110009454A1,CCCCI.Nc1ncccc1C(=O)NCc1cccc(O)c1F>>CCCCOc1cccc(CNC(=O)c2cccnc2N)c1F,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US04168269,CCCCCCI.O=C1Nc2ccccc2Nc2cscc21>>CCCCCCN1C(=O)c2cscc2Nc2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US05925769,COc1ccc(-n2nc(C#CCN(O)C(=O)Oc3ccccc3)cc2-c2ccc(C)cc2)cc1.N>>COc1ccc(-n2nc(C#CCN(O)C(N)=O)cc2-c2ccc(C)cc2)cc1,,CO,,,,test
US20090042929A1,COC(=O)c1cccc(OCC(=O)C23CC4CC(CC(C4)C2)C3)c1>>O=C(O)c1cccc(OCC(=O)C23CC4CC(CC(C4)C2)C3)c1,,CO,O,[Li+].[OH-],,test
US20130336918A1,O=C(Nc1cnc(-c2ccccc2)nc1)c1cc(N2CCCCC2)ccc1[N+](=O)[O-]>>Nc1ccc(N2CCCCC2)cc1C(=O)Nc1cnc(-c2ccccc2)nc1,[Pd],CCO,CCOC(C)=O,,,test
US04761404,CC(N)CO.CCCCCCCCCCCCCCCC(=O)Cl>>CCCCCCCCCCCCCCCC(=O)NC(C)CO,,ClCCl,,,,test
US20090036492A1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.Cc1cc(C)c(C=O)c(C)c1>>COc1cc(O)c2c(c1C(=O)NCc1c(C)cc(C)cc1C)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20070299083A1,COc1cc(N2CCNCC2)c2ncccc2c1.O=C1CCN(c2ccc(F)c3cccnc23)CC1>>COc1cc(N2CCN(C3CCN(c4ccc(F)c5cccnc45)CC3)CC2)c2ncccc2c1,,CO,,[BH3-]C#N.[Na+],,test
US20080004302A1,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cc(F)cc(C(F)(F)F)c1>>COC(=O)/C=C/c1cc(F)cc(C(F)(F)F)c1,,ClCCl,,,,test
US20110230463A1,COC(=O)C1(F)CCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CCC(F)(C(=O)O)C1,,CC(=O)O,,Cl,,test
US04587331,NN.O=C[C@H](O)[C@@H](O)[C@@H](O)CO>>NN=C[C@H](O)[C@@H](O)[C@@H](O)CO,,CO,,O,,test
US04867899,O=S(=O)(O)OS(=O)(=O)OS(=O)(=O)O.OCC(O)CO>>O=S(=O)(O)OS(=O)(=O)O.OCC(O)CO,,OCC(O)CO,,,,test
US20160009744A1,Cc1sc(C2OCCO2)cc1[C@H](O)c1cc(Cl)ccc1CCI>>Cc1sc(C2OCCO2)cc1[C@@H]1OCCc2ccc(Cl)cc21,O=[Ag-],CCOCC,,,,test
US20050159444A1,COC1(OC)CCN2C[C@H](N=[N+]=[N-])C[C@H]2C1>>[N-]=[N+]=N[C@@H]1C[C@H]2CC(=O)CCN2C1,,C1COCCO1,Cl,,,test
US20080207654A1,CCCCc1nc(C)n(CC2CCCO2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nc(C)n(CC2CCCO2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US05021443,CCOC(=O)CCCBr.Fc1ccc2c(c1)nc(S)n2Cc1ccc(Cl)cc1>>CCOC(=O)CCCSc1nc2cc(F)ccc2n1Cc1ccc(Cl)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04766144,O=C=Nc1ccc(OC(F)(F)F)cc1.O=c1cc(O)c2ccccc2o1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1c(O)c2ccccc2oc1=O,,CS(C)=O,O,CCN(CC)CC,Cl,test
US04803200,CC(N)CO.c1ccc([C@H]2O[C@@H]2c2ccccc2)cc1>>CC(CO)NC(c1ccccc1)C(O)c1ccccc1,,CO,,O,,test
US20060004011A1,O=c1[nH]c2ccccc2nc1-c1[nH]c2ccccc2c1[N+](=O)[O-]>>Nc1c(-c2nc3ccccc3[nH]c2=O)[nH]c2ccccc12,[Pd],C1CCOC1,CN(C)C=O,,,test
US20100234341A1,C1CCNC1.CC(=O)Nc1cc(Cl)nc(-n2nc(C)cc2C)n1>>CC(=O)Nc1cc(N2CCCC2)nc(-n2nc(C)cc2C)n1,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US03931151,CCOC(=O)C=C1Cc2ccccc2N(C)c2ccc(SCC)cc21>>CCSc1ccc2c(c1)C(CC(=O)O)=Cc1ccccc1N2C,,CCO,,Cl,[K+].[OH-],test
US20120196872A1,BrCc1ccccc1.CCOC(=O)C(N)C1CCOCC1>>CCOC(=O)C(NCc1ccccc1)C1CCOCC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120028961A1,CC(C)(C)NC(=O)c1ccc(C#N)cc1>>CC(C)(C)NC(=O)c1ccc(CN)cc1,[Ni],CO,,N,,test
US05106863,CC(C)=CCC/C(C)=C\CCl.Sc1nc2ccccc2[nH]1>>CC(C)=CCC/C(C)=C\CSc1nc2ccccc2[nH]1,,CO,,O,[Na+].[OH-],test
US20040138462A1,CCOC(=O)COc1ccc(S(=O)(=O)c2ccc(CCN(Cc3ccccc3)C[C@H](O)c3cccc(Cl)c3)cc2)cc1>>CCOC(=O)COc1ccc(S(=O)(=O)c2ccc(CCNC[C@H](O)c3cccc(Cl)c3)cc2)cc1,,CCOC(C)=O,,Cl,,test
US05514680,CCOC(=O)C(=O)OCC.Nc1ccc(F)cc1N>>O=c1[nH]c2ccc(F)cc2[nH]c1=O,,[Na+],[OH-],C,,test
US04429152,COC(=O)COc1c(Br)cc(Br)c(C(N)=O)c1Br>>NC(=O)c1c(Br)cc(Br)c(OCC(=O)O)c1Br,,O,,[Na+].[OH-],,test
US20090143355A1,O=c1[nH]cnc2ccc([N+](=O)[O-])cc12>>Nc1ccc2nc[nH]c(=O)c2c1,[Pd],CCO,,CO,,test
US04555513,COC(=O)C(C)c1ccc(NCCC(=O)O)c(Cl)c1>>COC(=O)C(C)c1cc(Cl)c2c(c1)C(=O)CCN2,,Cc1ccccc1,,[Na+].[OH-],,test
US20100035883A1,Brc1ccc(C2=NCCC2)cc1>>Brc1ccc(C2CCCN2)cc1,,CO,O,[BH4-].[Na+],,test
US20090170873A1,COCC(C)NC(=O)c1cc(I)cc(-c2ccc(C)cc2)c1.Cn1cc(B(O)O)cn1>>COCC(C)NC(=O)c1cc(-c2ccc(C)cc2)cc(-c2cnn(C)c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,Cc1ccccc1,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110312936A1,O=C1CCC(=O)N1.Oc1cccnc1C1=CCC2(CC1)OCCO2>>O=C1CCC(=O)N1C1CCC2(CC1)OCCO2,,CN(C)C=O,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20140288067A1,C1COCCN1.Cc1c(Cl)nc(-c2cccc(O)c2)nc1N[C@@H]1CCOC1>>Cc1c(N[C@@H]2CCOC2)nc(-c2cccc(O)c2)nc1N1CCOCC1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20070191342A1,CCOC(=O)N1CCc2scc(C)c2CC1.O=C1CCC(=O)N1Br>>CCOC(=O)N1CCc2sc(Br)c(C)c2CC1,,ClC(Cl)Cl,ClCCl,CC(=O)O,,test
US04617307,NC(=O)c1ccc(C2CCCc3cncn32)cc1.O=P(Cl)(Cl)Cl>>Cl.N#Cc1ccc(C2CCCc3cncn32)cc1,,ClC(Cl)Cl,,,,test
US05854234,COC1=NCC(C)CC(C)C1.[Cl-].[NH4+]>>CC1CNC(=N)CC(C)C1.Cl,,CO,,,,test
US06399828B1,CC(=O)Cc1ccccc1.NC=O>>CC(Cc1ccccc1)NC=O,,O=CO,,,,test
US04732998,CCI.CCOP(=O)(OCC)C(Oc1ccccc1)P(=O)(OCC)OCC>>CCOP(=O)(OCC)C(CC)(Oc1ccccc1)P(=O)(OCC)OCC,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20060205734A1,CC(C)(C)OC(=O)N1CCNCC1.O=C(Cl)c1cccs1>>O=C(O)N1CCN(C(=O)c2cccs2)CC1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20120040953A1,COc1ncc(-c2noc(COC3CCN(C(=O)OC(C)C)CC3)n2)cn1>>CC(C)OC(=O)N1CCC(OCc2nc(-c3cnc(O)nc3)no2)CC1,,CC#N,,C[Si](C)(C)Cl,[I-].[Na+],test
US04558040,COC(=O)Cl.Cc1ccc(NN)c2c1CCC(C)O2>>Cc1ccc(NNC(=O)O)c2c1CCC(C)O2,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US08129361B2,CC(C)(C)OC(=O)NC1(CCc2ccc(OCCCc3ccc(C(F)(F)F)cc3)c(C(F)(F)F)c2)COC(C)(C)OC1.Cl>>Cl.NC(CO)(CO)CCc1ccc(OCCCc2ccc(C(F)(F)F)cc2)c(C(F)(F)F)c1,,CCO,,,,test
US20070155805A1,CCOC(=O)COc1ccc(OCCC(CCOC)c2sc3cc(C(F)(F)F)ccc3c2C)cc1CC>>CCc1cc(OCCC(CCOC)c2sc3cc(C(F)(F)F)ccc3c2C)ccc1OCC(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20030036558A1,C=CCO.Nc1ccc(OCC(=O)O)c(C(=O)NCc2ccc(Br)cc2F)c1>>C=CCOC(=O)COc1ccc(N)cc1C(=O)NCc1ccc(Br)cc1F,O=S(=O)(O)O,,,,,test
US20060241115A1,COc1cc2nccc(C(O)c3ccc4cc(Br)ccc4c3)c2cc1OC>>COc1cc2nccc(Cc3ccc4cc(Br)ccc4c3)c2cc1OC,[Zn],O=CO,,,,test
US20140323468A1,CC(O)(c1cncc(Br)c1)C(F)(F)F.CC1(C)OB(c2cnc3c(c2)CCCN3C(N)=O)OC1(C)C>>CC(O)(c1cncc(-c2cnc3c(c2)CCCN3C(N)=O)c1)C(F)(F)F,,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],test
US04087524,CC(C)(C)[Si](C)(C)Cl.C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43CO)[C@@H]1CCC2=O>>CC(C)(C)[Si](C)(C)OC[C@]12CCC(=O)C=C1CC[C@H]1[C@@H]3CCC(=O)[C@@]3(C)CC[C@@H]12,,CN(C)C=O,,c1ccncc1,,test
US20040224945A1,Cc1nnc(S(C)(=O)=O)s1.N#CCC#N>>Cc1nnc(C(C#N)C#N)s1,,C1CCOC1,,[H-].[Na+],,test
US20140329797A1,CC(C)[Si](OCC1(c2cccc(Cn3cc(-c4nc(-c5ccc(OC(F)(F)F)cc5)no4)ccc3=O)c2)CC1)(C(C)C)C(C)C>>O=c1ccc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)cn1Cc1cccc(C2(CO)CC2)c1,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20040143009A1,CC=O.NCCCc1ccccc1>>CCNCCCc1ccccc1,,CCO,,[BH4-].[Na+],,test
US20110251190A1,C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)C1=NC2(CS1)c1cc(I)ccc1Oc1ncc(Br)cc12.OB(O)c1cccnc1>>C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)C1=NC2(CS1)c1cc(-c3cccnc3)ccc1Oc1ncc(Br)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US04564609,O=C(N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1)OCc1ccccc1>>N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1,,CCOCC,,Br,CC(=O)O,test
US05536718,COC(=O)c1ccc(N(C(=O)c2ccccc2-c2ccccc2)C(=O)c2ccccc2-c2ccccc2)nc1>>O=C(O)c1ccc(NC(=O)c2ccccc2-c2ccccc2)nc1,,C1CCOC1,CO,CC(=O)O,[Na+].[OH-],test
US08680122B2,CC1=CC(=O)OC1=O.COc1ccc(CN)cc1>>COc1ccc(CN2C(=O)C=C(C)C2=O)cc1,,CC(=O)O,,,,test
US20140323475A1,CC(C)(C)O[Na].O=C(O)c1cncc2c1ccn2Cc1cc(Cl)ccc1OCc1ccc(F)cc1F>>O=C([O-])c1cncc2c1ccn2Cc1cc(Cl)ccc1OCc1ccc(F)cc1F.[Na+],,CO,,,,test
US06245763B1,CCCOC12C=CC=C(NC(=O)OCc3ccccc3)C1C(=O)NC2=O.CCO.CN>>NOCCCNC(=O)OCc1ccccc1,,CCO,,C1CCOC1,,test
US20100087427A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1C[C@H](CN(Cc2ccccc2N)c2ccc(Cl)cc2)[C@@H](Cc2ccccc2)C1>>CC(=O)Nc1ccccc1CN(C[C@H]1CN(C(=O)OC(C)(C)C)C[C@@H]1Cc1ccccc1)c1ccc(Cl)cc1,,c1ccncc1,,,,test
US20160194278A1,COC(=O)c1ccc(OCCNC(=O)OC(C)(C)C)cc1C(=O)OC>>CC(C)(C)OC(=O)NCCOc1ccc(CO)c(CO)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05585394,CCOc1ccc2c(c1)n(C1CCCCC1)c(=O)n2S(=O)(=O)c1ccc(C(=O)O)cc1OC.Nc1nccs1>>CCOc1ccc2c(c1)n(C1CCCCC1)c(=O)n2S(=O)(=O)c1ccc(C(=O)Nc2nccs2)cc1OC,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20130203768A1,CC/C=C/C(=O)Cl.COc1cc(N2CCNCC2)n2nccc2n1>>CC/C=C/C(=O)N1CCN(c2cc(OC)nc3ccnn23)CC1,,ClCCl,,,,test
US20020161237A1,CC(C)C(N)=S.CCOC(=O)C(Cl)C(C)=O>>CCOC(=O)c1sc(C(C)C)nc1C,,CCO,,,,test
US20130143876A1,CCNC(=O)C(C)c1ccc(C2CCNCC2)cc1.COc1cc(OCC2CC2)ccc1Br>>CCNC(=O)C(C)c1ccc(C2CCN(c3ccc(OCC4CC4)cc3OC)CC2)cc1,[Cu]I,CS(C)=O,,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US20020193616A1,CCC(/C=C\CO[C@@H](C)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C)(CC)O[Si](CC)(CC)CC>>CCC(O)(/C=C\CO[C@@H](C)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C)CC,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080039444A1,CS(=O)(=O)Cl.OCCCOc1ccc2c(c1)CCN(C1CCC1)CC2>>CS(=O)(=O)OCCCOc1ccc2c(c1)CCN(C1CCC1)CC2,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110015157A1,CC(O)(CCN)c1ccccc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC1(c2ccccc2)CCNC(=O)O1,,ClCCl,O,CCN(CC)CC,,test
US05438052,CC(C)(ON)C(=O)NNC(=O)c1ccc(O)c(O)c1.Cc1cc(SCC2=C(C(=O)O)N3C(=O)[C@@H](NC(=O)C(=O)c4csc(N)n4)[C@H]3SC2)n2nc(C(=O)N(C)O)nc2n1>>Cc1cc(SCC2=C(C(=O)O)N3C(=O)[C@@H](NC(=O)/C(=N\OC(C)(C)C(=O)NNC(=O)c4ccc(O)c(O)c4)c4csc(N)n4)[C@H]3SC2)n2nc(C(=O)N(C)O)nc2n1,,CC(=O)N(C)C,,Cl,,test
US20140296067A1,N#CC1(c2ncc(C(F)(F)F)cc2Cl)CC1>>NCC1(c2ncc(C(F)(F)F)cc2Cl)CC1,[Ni],CO,,N,[H][H],test
US20100311748A1,Cc1ncccc1C#N.O=C1CCC(=O)N1Br>>N#Cc1cccnc1CBr,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20090093508A1,BrCCOCCBr.COC(=O)Cc1ccc(Br)cc1>>COC(=O)C1(c2ccc(Br)cc2)CCOCC1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20060287323A1,Cc1nc(C(F)(F)F)ccc1CCl.Oc1nnc(Cl)c(-c2ccc(Cl)cc2)c1-c1ccccn1>>Cc1nc(C(F)(F)F)ccc1Cn1nc(Cl)c(-c2ccc(Cl)cc2)c(-c2ccncc2)c1=O,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20160002251A1,Cc1cc(N=C=O)c(C(F)(F)F)o1.O=C1CC(=O)N(Cc2cccc(F)c2)N2CCC[C@@H]12>>Cc1cc(NC(=O)C2=C(O)[C@@H]3CCCN3N(Cc3cccc(F)c3)C2=O)c(C(F)(F)F)o1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20160137618A1,C[C@H](N)C(=O)OC(C)(C)C.N=C(c1ccccc1)c1ccccc1>>C[C@H](N=C(c1ccccc1)c1ccccc1)C(=O)OC(C)(C)C,,ClCCl,O,Cl,,test
US20120108583A1,O=Cc1ccc(F)cc1.O=[N+]([O-])O>>O=Cc1ccc(F)c([N+](=O)[O-])c1,,O=S(=O)(O)O,,,,test
US20060041144A1,COC(=O)C(=O)OC.Clc1ccc(Br)cc1>>COC(=O)C(=O)c1ccc(Cl)cc1,,C1CCOC1,,[Mg],[Cl-].[NH4+],test
US20080045507A1,Cl[Mg]C1CCCCC1.O=Cc1ccc(C(=O)N2CCCN(C3CC3)CC2)cc1>>O=C(c1ccc(C(O)C2CCCCC2)cc1)N1CCCN(C2CC2)CC1,,C1CCOC1,,,,test
US20100331378A1,CC1(c2csc(CO)n2)OCCO1.CS(=O)(=O)Cl>>CC1(c2csc(COS(C)(=O)=O)n2)OCCO1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,N#N,test
US20070213341A1,COC(=O)CC(=O)OC.COc1ccc(Cl)c([N+](=O)[O-])c1>>COc1ccc2c(c1)NC(=O)C2,[Fe],,,[H-].[Na+],,test
US20090227601A1,CCOC(C)=O.Cc1ccc(S(=O)(=O)N2C=CNC(=O)[C@H]2CC(=O)NC2CCNCC2(C)C)cc1>>CC(=O)N1CCC(NC(=O)C[C@@H]2C(=O)NC=CN2S(=O)(=O)c2ccc(C)cc2)C(C)(C)C1,,ClCCl,,CCN(CC)CC,,test
US20090181956A1,NN.O=c1oc(-c2cc(C(F)(F)F)nn2-c2ncccc2Cl)nc2c(Cl)cccc12>>NNC(=O)c1cccc(Cl)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl,,O,,C1CCOC1,,test
US20060264415A1,CCOC(C)=O.O=C(O)CC(O)C(=O)O>>CC1(C)OC(=O)C(CC(=O)O)O1,,CCOC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090239854A1,C=Cc1ccc(OC)nc1.CN1CCc2[nH]c3ccc(Cl)cc3c2C1>>COc1ccc(CCn2c3c(c4cc(Cl)ccc42)CN(C)CC3)cn1,,CN1CCCC1=O,,[K+].[OH-],,test
US20100135999A1,CCCCOC(=O)N1CCN(C(=O)[C@H](CC(F)F)NC(=O)OCc2ccccc2)CC1>>CCCCOC(=O)N1CCN(C(=O)[C@@H](N)CC(F)F)CC1,[Pd],CCOC(C)=O,,,,test
US20130109662A1,C=C1CC(=O)O1.OCC1CCCCN1>>CC(=O)CC(=O)N1CCCCC1CO,,C1CCOC1,,,,test
US20080255083A1,C1CCNC1.O=c1cc(OCc2ccc(F)cc2)ccn1CCc1ccc(CBr)cc1>>O=c1cc(OCc2ccc(F)cc2)ccn1CCc1ccc(CN2CCCC2)cc1,,CN(C)C=O,,,,test
US20110224204A1,COc1c(Br)cccc1C#N.OB(O)c1ccncc1>>COc1c(C#N)cccc1-c1ccncc1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20020019523A1,CC(C)(C)N.O=C(OCc1ccccc1)N1CCC(C(=O)O)(C2CCCCC2)CC1>>CC(C)(C)NC(=O)C1(C2CCCCC2)CCN(C(=O)OCc2ccccc2)CC1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US03959309,CN(C)C1CCc2[nH]c3c(Br)ccc(F)c3c2C1>>CN(C)C1CCc2[nH]c3cccc(F)c3c2C1,[Pd],O,,CO,[K+].[OH-],test
US20110028493A1,CCOC(=O)c1cnn(Cc2nc(Br)sc2C)c1.OB(O)c1cc(Cl)cc(C(F)(F)F)c1>>CCOC(=O)c1cnn(Cc2nc(-c3cc(Cl)cc(C(F)(F)F)c3)sc2C)c1,,CCO,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],test
US06521643B1,Cc1cc(OC(C)C)cc[n+]1[O-]>>Cc1cc(OC(C)C)ccn1,[Ni],CC(C)O,,,,test
US20160152561A1,NS(=O)(=O)c1cccc(NC(=O)c2ccc(C(F)(F)F)cc2F)c1.Oc1ccc(F)cc1>>NS(=O)(=O)c1cccc(NC(=O)c2ccc(C(F)(F)F)cc2Oc2ccc(F)cc2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04459232,CN1CCCNCC1.O=C1Nc2ccccc2Cc2nccn21>>CN1CCCN(C(=O)Nc2ccccc2Cc2ncc[nH]2)CC1,,ClCCl,,,,test
US20090182140A1,CC(C)(C)OC(=O)N1CCCC1C(=O)N1CCNCC1.Clc1ccc(CNc2cc(Cl)nc3ccnn23)c(Cl)c1>>CC(C)(C)OC(=O)N1CCCC1C(=O)N1CCN(c2cc(NCc3ccc(Cl)cc3Cl)n3nccc3n2)CC1,,C1COCCO1,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20060270609A1,CC(=O)OC[C@H]1O[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.C[Si](C)(C)N=[N+]=[N-]>>CC(=O)OC[C@H]1O[C@H](N=[N+]=[N-])[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,ClCCl,,Cl[Sn](Cl)(Cl)Cl,,test
US20140256700A1,BrCc1ccccc1.CCOC(=O)c1ccc2[nH]c3cc(Br)cc(C(N)=O)c3c2c1>>NC(=O)c1cc(Br)cc2c1c1cc(C(=O)O)ccc1n2Cc1ccccc1,,CC(C)=O,,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US20110257171A1,Ic1ccc2nccn2c1.OB(O)c1cccc(F)c1>>Fc1cccc(-c2ccc3nccn3c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,CN(C)C=O,O=C([O-])O.[Na+],test
US20090062360A1,O=C(Cl)C(=O)Cl.O=C(O)CN1C(=O)C(c2ccc(OC(F)(F)F)cc2)=NC12CCCCC2>>O=C(Cl)CN1C(=O)C(c2ccc(OC(F)(F)F)cc2)=NC12CCCCC2,CN(C)C=O,ClCCl,,,,test
US20090197864A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.C[C@@H](Oc1c(N)ncc2c(Br)coc12)c1c(Cl)ccc(F)c1Cl>>C[C@@H](Oc1c(N)ncc2c(C3=CCN(C(=O)OC(C)(C)C)CC3)coc12)c1c(Cl)ccc(F)c1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20120142917A1,Nc1ccc(O)c2ccccc12.O=S(=O)(Cl)c1cccs1>>O=S(=O)(Nc1ccc(O)c2ccccc12)c1cccs1,,CCN(CC)CC,,Cl,,test
US20030078239A1,CCOC(=O)C(C)(C)Cc1cccc(C(=O)c2cccc(CC(C)(C)C(=O)OCC)c2)c1>>CC(C)(Cc1cccc(C(=O)c2cccc(CC(C)(C)C(=O)O)c2)c1)C(=O)O,,CCO,O,[K+].[OH-],,test
US20030199422A1,CO.COC(=O)c1ccc(N)cc1.OCCCCCc1ccccc1>>CC(CCOC(=O)c1ccc(N)cc1)CCc1ccccc1,,Cc1ccccc1,,[H-].[Na+],,test
US20150216168A1,CCOC(=O)c1cccc(O)c1N.O=C(OC(=O)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)F>>CCOC(=O)c1cccc2oc(C(F)(F)C(F)(F)F)nc12,,O,,C1CCOC1,,test
US20100317865A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)[C@@H](CCC(=O)OCc1ccccc1)C(=O)OC1CCCC1>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)[C@@H](CCC(=O)O)C(=O)OC1CCCC1,[Pd],CCOC(C)=O,,,,test
US20040082780A1,CS(=O)(=O)Cl.Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)cccc2s1>>CS(=O)(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)cccc2s1,,CN(C)C=O,,CCN(CC)CC,,test
USH0001759,CS(=O)(=O)Cl.OCC1CCOCO1>>CS(=O)(=O)OCC1CCOCO1,,ClCCl,,CCN(CC)CC,,test
US05639752,CN1CCC[C@@H]1Cc1c[nH]c2ccc(N)cc12.O=[N+]([O-])c1cc(C(F)(F)F)ccc1Cl>>CN1CCCC1Cc1c[nH]c2ccc(Nc3ccc(C(F)(F)F)cc3[N+](=O)[O-])cc12,,CCO,,CCN(CC)CC,,test
US20160200725A1,CC(C)(C)OC(=O)N[C@@H]1CCCNC1.OCCBr>>CC(C)(C)OC(=O)N[C@@H]1CCCN(CCO)C1,,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US04845100,Nc1ccccc1.O=C1CCc2cc(C(=O)N(CCCl)CCCl)ccc2N1>>O=C1CCc2cc(C(=O)N3CCN(c4ccccc4)CC3)ccc2N1,,CO,,O=C([O-])[O-].[Na+].[Na+],,test
US20160229816A1,N#Cc1cc(Oc2ccccc2)cc(C(F)(F)F)c1.O=CO>>O=Cc1cc(Oc2ccccc2)cc(C(F)(F)F)c1,[Ni],CCOC(C)=O,,,,test
US03960868,CCOC(=O)c1cnc2ccc(C3CCCCC3)cc2c1O.ClCc1ccccc1>>COC(=O)c1cn(Cc2ccccc2)c2ccc(C3CCCCC3)cc2c1=O,,CO,,O,[Na],test
US20070219235A1,NCCN1CCOCC1.O=[N+]([O-])c1ccc2cn([N+](=O)[O-])nc2c1>>O=[N+]([O-])c1ccc2c(NCCN3CCOCC3)n[nH]c2c1,,C1CCOC1,CCOC(C)=O,,,test
US20080139539A1,N#CC(O)C1CCN(Cc2ccccc2)CC1>>NCC(O)C1CCN(Cc2ccccc2)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140315833A1,C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43C)[C@@H]1CCC2=O.O=C(O)CCCC(=O)O>>C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43C)[C@@H]1CCC2=O.O=C(O)CCCC(=O)O,,CC(C)=O,,,,test
US20130030012A1,CS(=O)(=O)OCc1cnc(Oc2ccc(F)c(F)c2)c(F)c1.C[Si](C)(C)C#N>>N#CCc1cnc(Oc2ccc(F)c(F)c2)c(F)c1,,CC#N,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040102449A1,C[C@H](NC(=O)OC(C)(C)C)c1cccc(Oc2ccccn2)c1>>C[C@H](N)c1cccc(Oc2ccccn2)c1,,C1COCCO1,,Cl,,test
US20050272931A1,CC(=O)c1ccc(B(O)O)cc1.Ic1ccnc(Nc2ccc3c(c2)OCCO3)c1>>CC(=O)c1ccc(-c2ccnc(Nc3ccc4c(c3)OCCO4)c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,,,test
US20040242942A1,FC(F)(F)c1ccc(C(F)(F)F)cc1.O=[N+]([O-])O>>O=[N+]([O-])c1cc(C(F)(F)F)ccc1C(F)(F)F,,O=S(=O)(O)O,,,,test
US04380644,CCN1C[C@@H](C(=O)OC(C)(C)C)NC1=O.C[C@@H](CSC(=O)c1ccccc1)C(=O)Cl>>CCN1C[C@@H](C(=O)OC(C)(C)C)N(C(=O)[C@H](C)CSC(=O)c2ccccc2)C1=O,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20130079338A1,C1=COCCC1.FC(F)(F)c1n[nH]c2ccc(Br)cc12>>FC(F)(F)c1nn(C2CCCCO2)c2ccc(Br)cc12,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100004271A1,CCC(C(=O)Cl)C(=O)Cl.CCOC(C)=O.CS(=O)(=O)NCc1ccc2cc(Oc3c(Br)cc(N)cc3Br)ccc2n1>>CS(=O)(=O)NCc1ccc2cc(Oc3c(Br)cc(NC(=O)CC(=O)O)cc3Br)ccc2n1,,C1CCOC1,,CCN(CC)CC,,test
US20110200557A1,CCCCN(C(=O)c1ccccc1F)c1nnc(-c2cc(C)nc(Cl)c2)s1>>CCCCN(C(=O)c1ccccc1F)c1nnc(-c2ccnc(C)c2)s1,[Pd],C1COCCO1,CCO,Cl,,test
US04410539,CCOC(=O)COc1ccc(Cc2cccnc2)cc1C(C)=O>>Cc1c(C(=O)O)oc2ccc(Cc3cccnc3)cc12,,CCO,,[Na],,test
US20140221311A1,O=S(=O)(CCCCl)c1ncccc1Br>>O=S(=O)(c1ncccc1Br)C1CC1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20110028447A1,CC(C)(C)OC(=O)N[C@H](c1nnc(N)o1)C(C)(C)C.O=C(Cl)C1CC1>>CC(C)(C)OC(=O)N[C@H](c1nnc(NC(=O)C2CC2)o1)C(C)(C)C,,c1ccncc1,,,,test
US20140162985A1,CC(=O)Nc1cc2c(cc1C)CC(=O)CCC2.OCCO>>CC(=O)Nc1cc2c(cc1C)CC1(CCC2)OCCO1,,CCOC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US20040242928A1,CS(=O)(=O)c1ccc(O)cc1.Cc1cc(C)cc(CCl)c1>>Cc1cc(C)cc(COc2ccc(S(C)(=O)=O)cc2)c1,,CCO,,O,[Na+].[OH-],test
US20120316165A1,CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(NC(=O)c3cnn(-c4cccc(OC(F)F)c4)c3)c(F)c2)C1.Cl>>Cl.O=C(Nc1ccc([C@H]2CNCCO2)cc1F)c1cnn(-c2cccc(OC(F)F)c2)c1,,C1COCCO1,,CCOCC,,test
US20080188533A1,CCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1)[C@@H](C)C=O.NO>>CCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1)[C@@H](C)C=NO,,O,,Cl,c1ccncc1,test
US20160075692A1,O=C(O)CN1CCN(c2cccc3c2cnn3-c2ccccc2F)C1=O.O[C@@H]1CCCNC1>>O=C(CN1CCN(c2cccc3c2cnn3-c2ccccc2F)C1=O)N1CCC[C@@H](O)C1,,CN(C)C=O,,Cl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150247002A1,C=C(C)C(=O)OC.CN(C)C=O.C[N+](C)(C)Cc1ccccc1.O.[OH-].c1ccc2c(c1)-c1ccccc1C2CCC1c2ccccc2-c2ccccc21>>COC(=O)C(C)CC1(CCC2(CC(C)C(=O)OC)c3ccccc3-c3ccccc32)c2ccccc2-c2ccccc21,,O,,Cl,,test
US20060014767A1,C1CNC1.CC(=O)N1CCC(C(=O)N(CCCN2CC3CNCC3C2)c2ccc(C)c(Cl)c2)CC1.O=C(Cl)c1cccnc1Cl>>CC(=O)N1CCC(C(=O)N(CCCN2CC3CN(C(=O)c4cccnc4N4CCC4)CC3C2)c2ccc(C)c(Cl)c2)CC1,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,,test
US20140005168A1,Cc1cncc(-c2cc3c(cn2)cnn3-c2cnc(C)c(N3CCC[C@H](NC(=O)OC(C)(C)C)C3)n2)n1>>Cc1cncc(-c2cc3c(cn2)cnn3-c2cnc(C)c(N3CCC[C@H](N)C3)n2)n1,,Cl,,C1COCCO1,,test
US20060019957A1,O=C1c2ccccc2C(=O)N1Cc1n[nH]c(=S)[nH]c1=O>>O=C1c2ccccc2C(=O)N1Cc1nnc[nH]c1=O,[Ni],CCO,,,,test
US20140322229A1,COC(=O)c1ccc(C(O)c2c3n(c4ccccc24)CN(C)CC3)cc1>>COC(=O)c1ccc(C(=O)c2c3n(c4ccccc24)CN(C)CC3)cc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20100249095A1,CC(C)(C)OC(=O)N1CCC2(CCN(c3ccc(F)cc3)CC2)C1>>Fc1ccc(N2CCC3(CCNC3)CC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040048868A1,Nc1ccccc1N.O=Cc1cc[nH]n1>>c1ccc2[nH]c(-c3cc[nH]n3)nc2c1,,CN(C)C=O,,O=S([O-])O.[Na+],,test
US20120202287A1,CCCCCCCCCCO.Clc1ncnc2[nH]cnc12>>CCCCCCCCCCn1cnc2c(Cl)ncnc21,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060211716A1,Cc1cccc(N)c1CN.FC(F)(F)c1cccc(N=C=S)c1>>Cc1cccc(N)c1CNC(=S)Nc1cccc(C(F)(F)F)c1,,CCOC(C)=O,,,,test
US20120035214A1,COCC(=O)NCCc1ccccc1-c1ccc([C@@H]2CN(C(=O)OC(C)(C)C)CC[C@H]2c2ccn(C)c(=O)c2)c(Cl)c1>>COCC(=O)NCCc1ccccc1-c1ccc([C@@H]2CNCC[C@H]2c2ccn(C)c(=O)c2)c(Cl)c1,,ClCCl,,C1COCCO1,Cl,test
US20140113882A1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.NC(=O)c1ccnc(Cl)c1.O=C(O)c1c(Cl)cncc1Cl>>N=C(NC(=O)c1c(Cl)cncc1Cl)c1ccnc(Cl)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05021435,CCCCCCCCCC(S)C(=O)O.CN(C)CCN=Cc1cccnc1>>CCCCCCCCCC1SC(c2cccnc2)N(CCN(C)C)C1=O,,Cc1ccccc1,,,,test
US20120010188A1,Nc1cnc(Br)cn1.O=C(CBr)c1cccc2c1OCCO2>>Brc1cn2cc(-c3cccc4c3OCCO4)nc2cn1,,CCO,,[Na+].[OH-],,test
US04371537,CS(=O)(=O)c1ccc(S(C)(=O)=O)nc1.Oc1ccc(Oc2ccccc2)cc1>>CS(=O)(=O)c1ccc(Oc2ccc(Oc3ccccc3)cc2)nc1,,C1CCOC1,,O,CC(C)(C)[O-].[K+],test
US20130130997A1,CC(C)(C)[Si](C)(C)Cl.CO[C@@]1(c2ccc(Cl)c(Cc3ccc(OCCOC4CC4)cc3)c2)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O>>CO[C@@]1(c2ccc(Cl)c(Cc3ccc(OCCOC4CC4)cc3)c2)O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O)[C@H]1O,CN(C)c1ccncc1,c1ccncc1,,,,test
US20080194586A1,O=C(OO)c1cccc(Cl)c1.O=Cc1ccccc1Oc1ccc(Cl)cc1>>Oc1ccc(Oc2ccc(Cl)cc2)cc1,,ClCCl,,O=C([O-])O.[Na+],,test
US20100168188A1,CCOC(=O)C#N.O=C1CCc2c1ccc1nn(Cc3ccccc3)cc21>>CCOC(=O)C1Cc2c(ccc3nn(Cc4ccccc4)cc23)C1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20100130540A1,BrBr.CNc1ccc(C(=O)c2ccc(Cl)cc2)cn1>>CNc1ncc(C(=O)c2ccc(Cl)cc2)cc1Br,,CC(=O)O,,O=C([O-])O.[Na+],,test
US04983601,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C1Nc2cc(Br)ccc2-n2ccc3cccc1c32>>S=C1Nc2cc(Br)ccc2-n2ccc3cccc1c32,,Cc1ccccc1,,,,test
US20040214888A1,COC(=O)/C=C/c1cc(O)c2c(c1)C(C(=O)OC)C(c1ccc(O)c(O)c1)O2.O=C1CCC(=O)N1Br>>Brc1ccc2c(c1)CCO2,,CC#N,,,,test
US20070179161A1,CC(C)c1cnn2c(-c3ccc(NS(C)(=O)=O)cc3)cc(Cl)nc12.OC1CCCCC1>>CC(C)c1cnn2c(-c3ccc(NS(C)(=O)=O)cc3)cc(OC3CCCCC3)nc12,,C1COCCO1,,O,[H-].[Na+],test
US20090181942A1,CCO.O=C(O)CC1SC(c2cccc(F)c2F)c2cc(Cl)ccc2NC1=O>>CCOC(=O)C[C@H]1S[C@H](c2cccc(F)c2F)c2cc(Cl)ccc2NC1=O,,Cl,,,,test
US20090274632A1,CCI.COc1ccc(CNS(=O)(=O)c2ccc(C(=O)O)cc2)cc1>>CCN(Cc1ccc(OC)cc1)S(=O)(=O)c1ccc(C(=O)O)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120035134A1,Brc1ccccc1Br.OB(O)c1ccc(Cl)cc1>>Clc1ccc(-c2ccccc2Br)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090264416A1,CC(C)(C)NC(=O)c1cccc(CN2CCN(C(=O)c3ccc(N)cc3F)CC2)c1.NCC1CC1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)(C)NC(=O)c1cccc(CN2CCN(C(=O)c3ccc(NC(=O)NCC4CC4)cc3F)CC2)c1,,CC#N,,,,test
US20050239841A1,COc1ccc([C@@]23CC[C@@H](N)C[C@@H]2N(C)CC3)cc1OC.Cl.N#Cc1ccc(N)cc1C(F)(F)F.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc([C@@]23CC[C@@H](NC(=O)Nc4ccc(C#N)c(C(F)(F)F)c4)C[C@@H]2N(C)CC3)cc1OC.Cl,,CCOCC,ClCCl,CCN(CC)CC,,test
US20130336920A1,O=C(NCc1cccc(C(F)(F)F)c1)c1ccnc(-c2cc(F)ccc2[N+](=O)[O-])c1.OC1CCC1>>O=C(NCc1cccc(C(F)(F)F)c1)c1ccnc(-c2cc(OC3CCC3)ccc2[N+](=O)[O-])c1,,CN(C)C=O,,[H-].[Na+],,test
US04514416,CN(C)c1ccc(C(=O)O)cc1.CS(=O)(=O)Oc1ccc(C(=N)N)cc1C(=O)c1ccccc1>>CN(C)c1ccc(C(=O)Oc2ccc(C(=N)N)cc2C(=O)c2ccccc2)cc1.CS(=O)(=O)O,,c1ccncc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US06057304,Nc1ccccc1C(=O)O.O=[N+]([O-])c1ccc(F)c([N+](=O)[O-])c1>>O=C(O)c1ccccc1Nc1ccc([N+](=O)[O-])cc1[N+](=O)[O-],,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20060009453A1,Cc1cc(N)ccc1Oc1ncccc1-c1ccncn1.O=C(O)Cc1cccc(C(F)(F)F)c1>>Cc1cc(NC(=O)Cc2cccc(C(F)(F)F)c2)ccc1Oc1ncccc1-c1ccncn1,,ClCCl,,ClCCCl,,test
US03954757,II.O=C(O)c1cc2ccccc2[nH]1.S=C1NCCN1>>I.O=C(O)c1[nH]c2ccccc2c1SC1=NCCN1,,CO,O,[I-].[K+],,test
US20150344423A1,CC(=O)c1ccc(S(=O)(=O)NC(C)(C)C)c(Cl)c1Cl.CCOC(=O)C(=O)OCC>>CCOC(=O)C(=O)CC(=O)c1ccc(S(=O)(=O)NC(C)(C)C)c(Cl)c1Cl,,CCO,,,,test
US20060252811A1,COC(=O)c1cc(Cl)cc(I)c1>>OCc1cc(Cl)cc(I)c1,,C1CCOC1,Cc1ccccc1,CC(C)C[AlH]CC(C)C,,test
US04225707,CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=CC(C)S[C@H]12)c1csc(NC=O)n1.Cl>>CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=CC(C)S[C@H]12)c1csc(N)n1.Cl,,CO,,CCOCC,,test
US20080293770A1,CC(C)(C)OC(=O)N1CCC(N)CC1.O=[N+]([O-])c1cc(C(F)(F)F)c(Br)cc1F>>CC(C)(C)OC(=O)N1CCC(Nc2cc(Br)c(C(F)(F)F)cc2[N+](=O)[O-])CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20020115654A1,CCOC(=O)C(Cc1ccc(OCCC2c3ccccc3Oc3ccccc32)cc1)OCC>>CCOC(Cc1ccc(OCCC2c3ccccc3Oc3ccccc32)cc1)C(=O)O,,CCO,,[Na+].[OH-],,test
US06949658B2,NC(=O)[C@@H](N)c1ccccc1>>NC(=O)C(N)c1ccccc1,,O,,,,test
US20040167160A1,CC(=O)c1cc2cccc(-c3cc(C(C)C)cc(C(C)C)c3OCC(F)F)c2o1.CCOC(=O)C(F)P(=O)(OCC)OCC>>CCOC(=O)C(F)=C(C)c1cc2cccc(-c3cc(C(C)C)cc(C(C)C)c3OCC(F)F)c2o1,,CN(C)C=O,,O,[H-].[Na+],test
US04900752,CC1(C)Oc2cc3nonc3cc2C(N)C1O.CN=C=S>>CNC(=S)NC1c2cc3nonc3cc2OC(C)(C)C1O,,ClCCl,,,,test
US20110275627A1,C#CCC(C)(C)C(=O)OCC.CC(C)(C)C(=O)Cl>>CCOC(=O)C(C)(C)CC#CC(=O)C(C)(C)C,[Cu]I,CCN(CC)CC,,,,test
US20120316151A1,Cc1cc(Br)ccc1N=C=O.NNC(=O)C[C@@H]1CCN(C(=O)C2CC2)C1>>Cc1cc(Br)ccc1NC(=O)NNC(=O)C[C@@H]1CCN(C(=O)C2CC2)C1,,ClCCl,,,,test
US20100063115A1,COc1cccc(N)c1.N#Cc1cc(-c2nnc(NCC(=O)O)o2)ccc1F>>COc1cccc(NC(=O)CNc2nnc(-c3ccc(F)c(C#N)c3)o2)c1,,CN(C)C=O,,Cl,,test
US20110086882A1,Cc1cn2nc(C)c(NC(=O)OC(C)(C)C)c2s1.FC(F)(Br)C(F)(F)Br>>Cc1nn2c(Br)c(C)sc2c1NC(=O)OC(C)(C)C,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US04959366,CNCCO.O=[N+]([O-])c1ccc(CCBr)cc1>>CN(CCO)CCc1ccc([N+](=O)[O-])cc1,,Cc1ccccc1C,,,,test
US20140200207A1,Brc1ccc(-c2ncc[nH]2)cc1.C[Si](C)(C)CCOCCl>>C[Si](C)(C)CCOCn1ccnc1-c1ccc(Br)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04381398,CCOC(=O)Cc1ccc(OCC(O)CNC(C)CCc2ccccc2)cc1.Cl>>CC(CCc1ccccc1)NCC(O)COc1ccc(CC(=O)O)cc1.Cl,,CCO,,,,test
US20120071467A1,CC(C)(C)O.CNc1ccc(C(=O)[O-])cc1>>CNc1ccc(C(=O)OC(C)(C)C)cc1,CN(C)c1ccncc1,,,CCN=C=NCCCN(C)C,Cl,test
US20130274260A1,N#Cc1cccc(B(O)O)c1.O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(CCl)cc1>>N#Cc1cccc(Cc2ccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)cc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,[I-].[Na+],,test
US20150148340A1,CCOC=C(C(=O)NC(=O)OCC)C(=O)OCC.CN1C(=O)C(C)(C)c2ccc(N)cc21>>CCOC(=O)c1cn(-c2ccc3c(c2)N(C)C(=O)C3(C)C)c(=O)[nH]c1=O,,CCO,O,Cl,CC(C)(C)[O-].[K+],test
US06025372,CCCCOC(=O)N1CCN(CC#N)CC1>>CCCCOC(=O)N1CCN(CCN)CC1,[Ni],CCO,,N,,test
US20070232594A1,O=C1CN(C(=O)c2ccc(N3CCCC3)cc2Cl)c2ccccc2CN1CCN1C(=O)c2ccccc2C1=O>>NCCN1Cc2ccccc2N(C(=O)c2ccc(N3CCCC3)cc2Cl)CC1=O,,CO,,NN,O,test
US20150196672A1,Cc1ccc(S(=O)(=O)OCCCF)cc1.O=Cc1ccc(-c2ccc(O)cc2)cc1>>O=Cc1ccc(-c2ccc(OCCCF)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05102881,Br[Mg]CCCc1ccccc1.O=Cc1ccc(OCc2ccc3ccccc3n2)cc1>>OC(CCCc1ccccc1)c1ccc(OCc2ccc3ccccc3n2)cc1,,C1CCOC1,,,,test
US20060276533A1,C[C@H]1CC[C@H](C(=O)N(c2cc(C3=CCCCC3)sc2C(=O)O)[C@@H]2CC[C@@H](O)CC2)CC1>>C[C@H]1CC[C@H](C(=O)N(c2cc(C3CCCCC3)sc2C(=O)O)[C@@H]2CC[C@@H](O)CC2)CC1,[Pd],CO,,,,test
US20040267010A1,Cc1ccc(S(=O)(=O)N2CCC[C@@H]2CCO)cc1[N+](=O)[O-]>>Cc1ccc(S(=O)(=O)N2CCC[C@@H]2CCO)cc1N,[Ni],C1CCOC1,CO,NN,O,test
US04931452,COc1cc(C(F)(F)F)cnc1OC>>COc1cc(C(F)(F)F)cnc1O,,CC(=O)O,,Br,,test
US20130190340A1,Cc1ccc(S(=O)(=O)NC(=N)NCCCC(NOC(=O)Cc2ccccc2)C(=O)NCCCCCCNC(=O)C(F)(F)F)cc1>>Cc1ccc(S(=O)(=O)NC(=N)NCCCC(NOC(=O)Cc2ccccc2)C(=O)NCCCCCCN)cc1,,CO,,O,[Li+].[OH-],test
US20140309213A1,Cc1c([C@@H](O)CN2CCN(CC(=O)c3ccc4c(c3)CCS4(=O)=O)CC2)ccc2c1COC2=O>>Cc1c([C@@H](O)CN2CCN(CC(O)c3ccc4c(c3)CCS4(=O)=O)CC2)ccc2c1COC2=O,,CO,,[BH4-].[Na+],,test
US20150225397A1,COc1ccccc1-c1nc(OC)c2c(n1)[C@@]1(c3ccccc3)CCC3(OCCO3)[C@@H](C)[C@@H]1CC2>>COc1ccccc1-c1nc(OC)c2c(n1)[C@@]1(c3ccccc3)CCC(=O)[C@@H](C)[C@@H]1CC2,,C1CCOC1,O,Cl,O=C([O-])O.[Na+],test
US20160176861A1,BrC(Br)(Br)Br.Cc1onc(-c2c(Cl)cccc2Cl)c1CO>>Cc1onc(-c2c(Cl)cccc2Cl)c1CBr,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04150135,CC(C)=CCBr.COc1cccc([C@@]23CCCC[C@H]2C(=O)NC(=O)C3)c1>>COc1cccc([C@@]23CCCC[C@@H]2C(=O)N(CC=C(C)C)C(=O)C3)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20090069365A1,CC(c1ccccc1)N1CC(C(=O)OC(C)(C)C)C(c2cc3ccccc3s2)C1>>CC(c1ccccc1)N1CC(C(=O)O)C(c2cc3ccccc3s2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100069310A1,CCOC(=O)Cc1ccc(CC)cc1.N#Cc1c(F)cc(Br)cc1F>>CCc1ccc(Cc2cc(Br)cc(F)c2C#N)cc1,,CN1CCCC1=O,,Cl,CC(C)(C)[O-].[K+],test
US20030008849A1,CNCC(=O)OC(C)(C)C.O=S(=O)(Cl)c1ccc(OCC#Cc2ccc(Cl)cc2)cc1>>CN(CC(=O)OC(C)(C)C)S(=O)(=O)c1ccc(OCC#Cc2ccc(Cl)cc2)cc1,,ClC(Cl)Cl,c1ccncc1,Cl,,test
US20080194670A1,OCCCc1ccc(CO)cc1>>O=Cc1ccc(CCCO)cc1,O=[Mn]=O,CCO,,,,test
US20090275578A1,COC(=O)c1c(C)cc(F)cc1I.NC(=O)CCC(=O)NBr>>COC(=O)c1c(I)cc(F)cc1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20100173905A1,COc1cc(C(=O)O)c2c(c1C)OC(=O)c1c(C)cc(O)c(C=O)c1O2.NN>>COc1cc(C(=O)O)c2c(c1C)OC(=O)c1c(C)cc(O)c(C=NN)c1O2,,CCO,,O,,test
US20080015199A1,BrCCOC1CCCCO1.C#Cc1cc(O)cc(C(=Nc2ccc(-c3noc(C)n3)cc2)C(=NC(=O)OC)SC)c1>>C#Cc1cc(OCCOC2CCCCO2)cc(C(=Nc2ccc(-c3noc(C)n3)cc2)C(=NC(=O)OC)SC)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04496584,C/C=C/C=C/C(=O)O.CS(=O)(=O)Oc1ccc2cc(C(=N)N)ccc2c1>>C/C=C/C=C/C(=O)Oc1ccc2cc(C(=N)N)ccc2c1,,c1ccncc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20050148627A1,CC(C)CCN.CCOC(=O)C1=Cc2cc(Cl)c(F)cc2OC1C(F)(F)F>>CCOC(=O)C1=Cc2cc(Cl)c(NCCC(C)C)cc2OC1C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05494897,COC(=O)C[C@@H](NC(=O)[C@@H](Cc1c(C#N)[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>COC(=O)C[C@@H](NC(=O)[C@H](N)Cc1c(C#N)[nH]c2ccccc12)C(=O)OC(C)(C)C,,O=CO,,,,test
US06288082B1,COc1cccc2c(Cl)c(C#N)cnc12.Nc1ccc2cn[nH]c2c1>>COc1cccc2c(Nc3ccc4cn[nH]c4c3)c(C#N)cnc12,,CCOCCO,,Cl,c1ccncc1,test
US20090247524A1,CC(C)(C)[Si](C)(C)Cl.Oc1cc(I)c(Cl)cc1Cl>>CC(C)(C)[Si](C)(C)Oc1cc(I)c(Cl)cc1Cl,,O,,CN(C)C=O,c1c[nH]cn1,test
US20030181519A1,COc1ccc([Mg]Br)cc1.COc1ccc2cc(Br)ccc2c1>>COc1ccc(-c2ccc3cc(OC)ccc3c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cl,,C1CCOC1,,test
US20070066624A1,COC(=O)c1ccc2c(c1)CN(C)C2=O>>CN1Cc2cc(CO)ccc2C1=O,,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US20160039838A1,COc1cc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1N.O=C(Cl)/C=C/CBr>>COc1cc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)/C=C/CBr,,C1CCOC1,,O,,test
US06271406B1,C[Si](C)(Cl)C=C[Si](C)(C)Cl>>C[Si](C)(Cl)CC[Si](C)(C)Cl,[Pd],,,,,test
US20040122237A1,CNc1ccc(Oc2ccnc(C(N)=O)c2)cc1[N+](=O)[O-]>>CNc1ccc(Oc2ccnc(C(N)=O)c2)cc1N,[Pd],CO,,,,test
US20130121994A1,CCNCCOCC.CCOc1cc(C(=O)O)ccc1Br>>CCOc1cc(C(=O)N(CC)CCOC)ccc1Br,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04935413,CC(CCl)C(=O)N=C=O.OC(C(F)(F)F)C(F)(F)F>>CC(CCl)C(=O)NC(=O)OC(C(F)(F)F)C(F)(F)F,,ClC(Cl)Cl,,,,test
US20110142826A1,CCC(C(=O)Cl)C(=O)Cl.CN(C)C=O.Nc1ccc(I)cc1F>>CCOC(=O)CC(=O)Nc1ccc(I)cc1F,CN(C)c1ccncc1,,,CCN(CC)CC,,test
US05157041,CC(C)(C)C1(C(N)=O)NCCc2c1[nH]c1ccccc21.O=C(N[C@@H](Cc1ccccc1)[C@H]1CO1)OCc1ccccc1>>CC(C)(C)NC(=O)C1c2[nH]c3ccccc3c2CCN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1,,CO,,,,test
US05041448,C=Cc1ccccn1.Fc1ccc(Cn2c(NC3CCNCC3)nc3cncnc32)cc1>>Fc1ccc(Cn2c(NC3CCN(CCc4ccccn4)CC3)nc3cncnc32)cc1,,CCCCO,,,,test
US20090281103A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Clc1ccc(Br)cc1CNC1CC1>>CC(C)(C)OC(=O)N(Cc1cc(Br)ccc1Cl)C1CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20130018033A1,COC(=O)c1cncc2c(N(Cc3ccc(OC)cc3)Cc3ccc(OC)cc3)ncnc12>>COc1ccc(CN(Cc2ccc(OC)cc2)c2ncnc3c(C(=O)O)cncc23)cc1,,C1CCOC1,O,CC(=O)O,[Li+].[OH-],test
US20120122846A1,CC(C)(C)OC(=O)N1CCC2(CCNCC2)C1.Clc1nc(Cl)c2occc2n1>>CC(C)(C)OC(=O)N1CCC2(CCN(c3nc(Cl)nc4ccoc34)CC2)C1,,C1COCCO1,,CCOC(C)=O,O,test
US20130072677A1,CNC(=O)[C@@](C)(C(=O)NOCc1ccccc1)N(C)C(=O)c1ccc(-c2ccccc2)cc1>>CNC(=O)[C@@](C)(C(=O)NO)N(C)C(=O)c1ccc(-c2ccccc2)cc1,[Pd],CO,,[H][H],,test
US20100249402A1,N#Cc1ccc(OCCCCCOc2ccc(C(=O)CBr)cc2)cc1.NC(N)=S>>N#Cc1ccc(OCCCCCOc2ccc(-c3csc(N)n3)cc2)cc1,,CCO,,,,test
US20130225524A1,CCOC(=O)c1cccc(N)c1.NC(=O)c1cnc2cc(Cl)ccc2c1Cl>>CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(Cl)ccc23)c1,,CC(=O)O,O,,,test
US20140121206A1,CCOc1ccc(N)cn1.C[C@]1(Cn2cnc3ccc(C#N)cc32)CCC[C@@]2(CO2)C1>>CCOc1ccc(NC[C@]2(O)CCC[C@](C)(Cn3cnc4ccc(C#N)cc43)C2)cn1,,CO,,,,test
US20090099177A1,Nc1ccccn1.O=C(O)c1cccc(Cc2cc(Cl)ccc2OCc2ccccc2)n1>>O=C(Nc1ccccn1)c1cccc(Cc2cc(Cl)ccc2OCc2ccccc2)n1,,CCOC(C)=O,ClCCl,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20140099316A1,CC(C)CC1(C(=O)O)CCN(C(=O)OC(C)(C)C)CC1>>CC(C)CC1(C(=O)O)CCNCC1,,C1COCCO1,,Cl,,test
US20130210796A1,CC(=O)OCC(=O)Cl.Nc1ccc(S(F)(F)(F)(F)F)cc1>>CC(=O)OCC(=O)Nc1ccc(S(F)(F)(F)(F)F)cc1,,ClCCl,,CCN(CC)CC,,test
US20140275548A1,CCOC(=O)Cc1cc2ccc(OCc3cccc(Cl)c3)cc2[nH]c1=O.N>>NC(=O)Cc1cc2ccc(OCc3cccc(Cl)c3)cc2[nH]c1=O,,CO,,,,test
US20120071460A1,CCOC(=O)c1cnn(CC(C)(C)C)c1-c1ccncc1.NC(=NO)c1ccc(CO)cc1>>CC(C)(C)Cn1ncc(-c2nc(-c3ccc(CO)cc3)no2)c1-c1ccncc1,,C1CCOC1,,O,[H-].[Na+],test
US04730006,CI.OCCCC(F)(F)COCc1ccccc1>>COCCCC(F)(F)COCc1ccccc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20140323475A1,CCc1cc(Cl)ccc1CBr.COC(=O)c1cccc2c1ccn2Cc1cc(Cl)ccc1O>>CCc1cc(Cl)ccc1COc1ccc(Cl)cc1Cn1ccc2c(C(=O)OC)cccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130281449A1,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(NC(=O)c3ncc(C#N)cc3Cl)ccc2F)CO[C@@]1(C)C(F)(F)F>>C[C@@]1(C(F)(F)F)OC[C@@](C)(c2cc(NC(=O)c3ncc(C#N)cc3Cl)ccc2F)N=C1N,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20150266916A1,OC(c1ccc(OC(F)(F)F)cc1)c1cc(Br)ccc1Cl>>FC(F)(F)Oc1ccc(Cc2cc(Br)ccc2Cl)cc1,,ClCCl,,,,test
US20140011800A1,CC1(C)OB(c2ccc(O)nc2)OC1(C)C.CI>>Cn1cc(B2OC(C)(C)C(C)(C)O2)ccc1=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040110754A1,CON(C)C(=O)C1CC1c1cc(F)ccc1F.[OH-]>>O=C(O)C1CC1c1cc(F)ccc1F,,CO,,O,,test
US20140271460A1,CC(C)[C@H](CNC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1>>CC(C)[C@@H](N)CNC(=O)OC(C)(C)C,[Pd],,,,,test
US04804668,CN.COC(=O)c1nc(C)c(-c2ccncc2)s1>>CNC(=O)c1nc(C)c(-c2ccncc2)s1,,CCO,,,,test
US20140158859A1,C1CCOC1.CC1(C)c2ccccc2-c2ccc(Br)c3cccc1c23.c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CC1(C)c2ccccc2-c2ccc(-c3ccc4c5c(cccc35)C(C)(C)c3ccccc3-4)c3cccc1c23,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,[Mg],,test
US20030120079A1,COC(=O)CCCCCCN1C(=O)CC[C@@H]1C=O.COP(=O)(CC(=O)c1cccc(Br)c1)OC>>COC(=O)CCCCCCN1C(=O)CC[C@@H]1/C=C/C(=O)c1cccc(Br)c1,,COCCOC,,[H-].[Na+],,test
US20160194302A1,CN(C)C1CCN(C(=O)CCc2nccn2CCO)CC1.Cl>>CN(C)C1CCN(C(=O)CCc2nccn2CCO)CC1.Cl,,CCOCC,,ClCCl,,test
US20160214971A1,CC1(C)OB(c2cnc(F)c(Cl)c2)OC1(C)C.Cc1cc(C(=O)NS(C)(=O)=O)c(F)cc1Br>>Cc1cc(C(=O)NS(C)(=O)=O)c(F)cc1-c1cnc(F)c(Cl)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20080275029A1,Nc1ccc2c(=O)[nH]cnc2c1.O=C=Nc1ccc(Cl)cc1>>O=C(Nc1ccc(Cl)cc1)Nc1ccc2c(=O)[nH]cnc2c1,,C1COCCO1,,,,test
US20160272651A1,COC(CN)OC.O=C=Nc1ccc(Br)cc1>>O=c1[nH]ccn1-c1ccc(Br)cc1,,C1CCOC1,O,,,test
US20120289526A1,O=[N+]([O-])c1ccc(F)cc1.Oc1ccc(F)c(Cl)c1>>O=[N+]([O-])c1ccc(Oc2ccc(F)c(Cl)c2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090170921A1,COCCn1c(-c2ccc(C(C)C)cc2)nc2cc(C(OC(C)=O)c3ccccc3)cc(OC)c21>>COCCn1c(-c2ccc(C(C)C)cc2)nc2cc(Cc3ccccc3)cc(OC)c21,[Pd],C1CCOC1,,CO,,test
US20130203776A1,COc1ncc(F)cc1[C@@H](CO)Nc1ccn2ncc(C(=O)NCCCCl)c2n1.O=C(n1ccnc1)n1ccnc1>>COc1ncc(F)cc1[C@H]1COC(=O)N1c1ccn2ncc(C(=O)NCCCCl)c2n1,,CC#N,,,,test
US04565817,C=Cc1noc(C)n1.Cn1c(=O)c2[nH]cnc2n(C)c1=O>>Cc1nc(CCn2cnc3c2c(=O)n(C)c(=O)n3C)no1,,CN(C)C=O,,,,test
US20140066488A1,CCC/C=C/C(=O)OCC.CS(N)(=O)=O.O>>CCC[C@H](O)[C@@H](O)C(=O)OCC,,CC(C)(C)O,,,,test
US20110251186A1,O=C(c1cc(Br)ccc1F)c1cc(Cl)nc(F)c1O>>O=c1c2cc(Br)ccc2oc2c(F)nc(Cl)cc12,,C1COCCO1,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20110294776A1,CC(C)(C)OC(=O)N1CCC(c2cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c3c(N)ncnn23)C1>>Nc1ncnn2c(C3CCNC3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160052930A1,CSc1nccc(O)n1.Nc1ccc(C(=O)O)cc1>>O=C(O)c1ccc(Nc2nccc(O)n2)cc1,,COCCOCCOC,,,,test
US20130310377A1,CCN(CC)S(F)(F)F.O=[N+]([O-])c1ccc(-n2nc(C(F)(F)F)cc2CO)cc1>>O=[N+]([O-])c1ccc(-n2nc(C(F)(F)F)cc2CF)cc1,,ClCCl,,,,test
US20020052417A1,CCOC(=O)CNC(=O)Nc1ccc(C(=N)N)cc1>>N=C(N)c1ccc(NC(=O)NCC(=O)O)cc1,,CCO,,[Na+].[OH-],,test
US20100016319A1,CSc1cccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2O)c1.Clc1ccnc(Cl)n1>>CSc1cccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2Oc2ccnc(Cl)n2)c1,,CC(C)=O,,[Na+].[OH-],[Cl-].[NH4+],test
US20090181942A1,COc1cccc(C2OC(CC3OCCO3)c3nccn3-c3ccc(Cl)cc32)c1OC>>COc1cccc(C2OC(CCO)c3nccn3-c3ccc(Cl)cc32)c1OC,,ClCCl,,[O-][Cl+3]([O-])([O-])O,,test
US20100168094A1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(OCc2ccccc2)c(C2CCCC2)c1>>CCOC(=O)C=Cc1ccc(OCc2ccccc2)c(C2CCCC2)c1,,ClCCl,,,,test
US20160185779A1,CC(N)c1ccccc1.O=C(n1ccnc1)n1ccnc1.c1ccc(-c2n[nH]c3c2CNCC3)cc1>>CC(NC(=O)N1CCc2[nH]nc(-c3ccccc3)c2C1)c1ccccc1,,ClCCl,,O,,test
US20110178053A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.CCN(CC)CCCO>>CCN(CC)CCCn1cc(B2OC(C)(C)C(C)(C)O2)cn1,,C1CCOC1,ClCCl,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120225854A1,CCOC(=O)[C@H](Cc1ccnc(OC)c1)NC(=O)CN>>COc1cc(CC2NC(=O)CNC2=O)ccn1,,CO,,CCN(C(C)C)C(C)C,,test
US07071175B1,CCOC(=O)CC(=O)OCC.Cc1cc(CBr)cnc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>CCOC(=O)C(Cc1cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(C)c1)C(=O)OCC,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US05527799,CS(=O)(=O)Cl.O=C1N[C@H](CO)C[C@H]1Cc1ccccc1>>CS(=O)(=O)OC[C@@H]1C[C@@H](Cc2ccccc2)C(=O)N1,,ClCCl,,CCN(CC)CC,,test
US04965282,CC(C)=O.CI.Oc1ccc(Cl)c(Cl)c1O>>COc1ccc(Cl)c(Cl)c1OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04595677,COC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(C)C>>COC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)C[C@H](O)[C@@H](N)CC(C)C)C(C)C,,CO,,O=C=O,,test
US04444867,CC(=O)Nc1cccc2c(OC(C)=O)c(S(=O)(=O)Cl)ccc12.CC(C)(C)N>>CC(=O)Nc1cccc2c(OC(C)=O)c(S(=O)(=O)NC(C)(C)C)ccc12,,CC(C)=O,,,,test
US06265349B1,C#CCO.Cn1c(C(F)(F)F)ccc(-c2cc(CBr)c(Cl)cc2F)c1=O>>C#CCOCc1cc(-c2ccc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl,,CN(C)C=O,,O,[H-].[Na+],test
US20030004353A1,CC(=O)NCCCc1ccc(CCCNC(C)=O)nc1>>NCCCc1ccc(CCCN)nc1,,Cl,,[Na+].[OH-],,test
US20160024053A1,II.O=C(c1ccc2cc[nH]c2c1)N1CCOCC1>>O=C(c1ccc2c(I)c[nH]c2c1)N1CCOCC1,,CN(C)C=O,O,[K+].[OH-],,test
US20090163586A1,Cc1ccc2c(c1)S(=O)(=O)NC(=O)N2>>Cc1ccc(N)c(S(N)(=O)=O)c1,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20080188569A1,CC(C)CCCCCCCCCCCCCCC(=O)O.O.OCC(O)COCC(O)CO>>CC(C)CCCCCCCCCCCCCCC(=O)O.OCC(O)CO.OCC(O)CO,,O,,,,test
US20140290748A1,CCCCCCCCc1ccc(-c2ccsc2)cc1.O=C1CCC(=O)N1Br>>CCCCCCCCc1ccc(-c2ccsc2Br)cc1,,CN(C)C=O,,,,test
US20040063954A1,CC(=O)NC[C@H]1CN(c2ccc(N3CCC(=O)CC3)c(F)c2)C(=O)O1.N#CCC1CC1>>CC(=O)NC[C@H]1CN(c2ccc(N3CCC(=CC4(C#N)CC4)CC3)c(F)c2)C(=O)O1,,Cc1ccccc1,,C,O=C[O-].[NH4+],test
US20050059702A1,COC(=O)c1ccc(C)c([N+](=O)[O-])c1>>COC(=O)c1ccc(C)c(N)c1,[Pd],CO,,CCOC(C)=O,,test
US20060128685A1,COC(=O)C(=O)CC(=O)c1ccc(N(C)C)cc1.NNc1ccc(Cl)nn1>>COC(=O)c1cc(-c2ccc(N(C)C)cc2)n(-c2ccc(Cl)nn2)n1,,CO,,,,test
US04470826,Cc1cc(N)c([N+](=O)[O-])cc1N.OCCCCl>>Cc1cc(N)c([N+](=O)[O-])cc1NCCCO,,O,,O=C([O-])[O-].[Ca+2],,test
US20150225404A1,Clc1cc(-c2cccnc2)c2c(n1)CCCC2.OCc1ncco1>>c1cncc(-c2cc(OCc3ncco3)nc3c2CCCC3)c1,,CCOC(C)=O,CS(C)=O,O,[H-].[Na+],test
US20100075965A1,CC(C)(C)OC(=O)NCCC(=O)Nc1ccccn1.C[Si](C)(C)I>>I.NCCC(=O)Nc1ccccn1,,CC#N,,CO,,test
US20070129355A1,COC(=O)Cc1cnc(Cc2ccc(NC(=O)OCc3ccccc3)cc2)nc1N(C)C>>CN(C)c1nc(Cc2ccc(NC(=O)OCc3ccccc3)cc2)ncc1CC(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20050070549A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.NCc1ccc(Cl)cc1>>CC(C)(C)OC(=O)N1CCC(NCc2ccc(Cl)cc2)CC1,,CCOC(C)=O,ClCCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20080306122A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H]1CC[C@H](c2ccc(Br)cc2)N1>>COC(=O)[C@@H]1CC[C@H](c2ccc(Br)cc2)N1C(=O)OC(C)(C)C,,ClCCl,,,,test
US06048861,CC(=O)CCNC(=O)OC(C)(C)C.Nc1ncccc1C=O>>CC(C)(C)OC(=O)NCCc1ccc2cccnc2n1,,CCO,,[K+].[OH-],,test
US20090291951A1,CS(=O)(=O)Cl.Nc1nccc(CO)n1>>CS(=O)(=O)OCc1ccnc(N)n1,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20150232454A1,N#Cc1ccc(-c2[nH]c(=O)c(O)cc2-c2ccc(F)cc2)cc1.[N-]=[N+]=[N-]>>O=c1[nH]c(-c2ccc(-c3nnn[nH]3)cc2)c(-c2ccc(F)cc2)cc1O,,CC(=O)O,,CN(C)C=O,,test
US05993780,CC(=O)OCC(=O)Cl.CC(=O)OCc1c(I)c(N)c(I)c(C(=O)NCC(COC(C)=O)OC(C)=O)c1I>>CC(=O)OCC(=O)Nc1c(I)c(COC(C)=O)c(I)c(C(=O)NCC(COC(C)=O)OC(C)=O)c1I,,CC(=O)N(C)C,,O=C([O-])O.[Na+],,test
US06329547B1,CCOC(=O)C(=O)OCC.Cc1ccc([Mg]Br)cc1>>CCOC(=O)C(=O)c1ccc(C)cc1,,C1CCOC1,CCOCC,Cl,,test
US06291455B1,COCCOc1cc2ncnc(Cl)c2cc1OC.Nc1ccc(Br)cc1F>>COCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1OC.Cl,,CC(C)O,,,,test
US04185992,O=S(Cl)Cl.OCc1ccc(Br)c(Br)c1>>ClCc1ccc(Br)c(Br)c1,,ClC(Cl)Cl,,,,test
US05523403,C1COCCO1.CC(=O)NCC1CN(c2cc(F)c([Sn](C)(C)C)c(F)c2)C(=O)O1.Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1>>COc1ccc(-c2c(F)cc(N3CC(CNC(C)=O)OC3=O)cc2F)ccc1=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,,,test
US05364931,C(=NC1CCCCC1)=NC1CCCCC1.CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)O.On1nnc2ccccc21>>C=CCC(NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)c1ccccc1,,ClCCl,,CN1CCOCC1,,test
US20050133762A1,CCCC1CCc2ccc(F)c(F)c2C1.II>>CCCC1CCc2cc(I)c(F)c(F)c2C1,,C1CCOC1,,Cl,[Li]CCCC,test
US20020128321A1,COc1ccsc1C(=O)O.Nc1ccc([N+](=O)[O-])cc1O.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>COc1ccsc1NC(=O)Nc1ccc([N+](=O)[O-])cc1O,,Cc1ccccc1,,CCN(CC)CC,,test
US20140323477A1,CCn1c(=O)c(-c2ccc(S(=O)(=O)N3CCCC3)cc2C)cc2cnc(SC)nc21.O=C(OO)c1cccc(Cl)c1>>CCn1c(=O)c(-c2ccc(S(=O)(=O)N3CCCC3)cc2C)cc2cnc(S(C)=O)nc21,,ClCCl,,,,test
US20050037999A1,Clc1ncnc2c1ccn2C1CCCC1.O=C1CCC(=O)N1Br>>Clc1ncnc2c1c(Br)cn2C1CCCC1,,ClCCl,,,,test
US20110275611A1,CNC.CNc1nc(Cl)cc(N2C[C@@H](COS(C)(=O)=O)OC[C@H]2C)n1>>CNc1nc(Cl)cc(N2C[C@@H](CN(C)C)OC[C@H]2C)n1,,O,,O=C([O-])O.[Na+],,test
US04535076,Cc1ccc(S(=O)(=O)OCC(F)(F)F)cc1.Oc1ccc(S)cc1>>Oc1ccc(SCC(F)(F)F)cc1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20160009667A1,CC(C)Oc1ncc(B2OC(C)(C)C(C)(C)O2)cc1Cl.OO>>CC(C)Oc1ncc(O)cc1Cl,,C1CCOC1,,[Na+].[OH-],,test
US20150011546A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCc1cc(C)[nH]c(=O)c1C#N>>CCc1cc(C)[nH]c(=O)c1CNC(=O)OC(C)(C)C,[Ni],C1CCOC1,CO,CCN(CC)CC,,test
US20110245242A1,Clc1ncc(Cl)c(NC2CC2)n1.Nc1ccc(I)cc1>>Clc1cnc(Nc2ccc(I)cc2)nc1NC1CC1,,C1COCCO1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US06653334B1,C=CCOC(=O)Cc1cccc(OC(C)(C)C(=O)OC(C)(C)C)c1>>CC(C)(C)OC(=O)C(C)(C)Oc1cccc(CC(=O)O)c1,,C1CCOC1,CO,[Na+].[OH-],,test
US20060135578A1,CCOC(=O)Cc1ccc(-c2nc(CCl)c(C)o2)cc1.COC(=O)c1cc(O)no1>>CCOC(=O)Cc1ccc(-c2nc(COc3cc(C(=O)OC)on3)c(C)o2)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20160159737A1,CC/C=C\C/C=C\C/C=C\C/C=C\CC/C=C/CS.O=C(CBr)C(F)(F)F>>CC/C=C\C/C=C\C/C=C\C/C=C\CC/C=C/CSCC(=O)C(F)(F)F,,CCO,O,O=C([O-])O.[Na+],,test
US20050043395A1,COc1cc2c(Cl)ncnc2cc1OCc1ccccc1.Cl.Nc1ccc(Br)cc1F>>COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCc1ccccc1.Cl,,CC(C)O,,,,test
US05883049,BrC1CCCC1.O=C1C2=CCCCN2C(=O)N1c1cc(O)c(Cl)cc1F>>O=C1C2=CCCCN2C(=O)N1c1cc(OC2CCCC2)c(Cl)cc1F,,CC#N,CCOCC,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20050239780A1,C=C(C)C.Cc1ccc([C@@H](C(=O)O)C2CCOCC2)cc1>>Cc1ccc([C@@H](C(=O)OC(C)(C)C)C2CCOCC2)cc1,,ClCCl,,O=S(=O)(O)O,,test
US20120277212A1,CC(C)(C)ON=c1cc(-c2cc3cccn3cn2)oc2ccc(C=O)cc12.NCc1ccc(F)cc1>>CC(C)(C)ON=c1cc(-c2cc3cccn3cn2)oc2ccc(CNCc3ccc(F)cc3)cc12,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090111983A1,CC(C)[C@@H](CO)NC(=O)C1(NC(=O)OCc2ccccc2)CCCCC1>>CC(C)[C@@H](C=O)NC(=O)C1(NC(=O)OCc2ccccc2)CCCCC1,,CS(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20080081833A1,Cc1ccc(N=C=O)cc1.Nc1c2c(nn1-c1ccccc1)CSC2>>Cc1ccc(NC(=O)Nc2c3c(nn2-c2ccccc2)CSC3)cc1,,ClCCl,,,,test
US20080085886A1,CC1(C)OC[C@H](CONC(=O)c2oc3ccncc3c2Nc2c(F)cc(I)cc2F)O1>>O=C(NOC[C@H](O)CO)c1oc2ccncc2c1Nc1c(F)cc(I)cc1F,,CO,,,,test
US20050215572A1,CC(=O)N1Cc2cc(Nc3ncnc4c3CCN(c3ncccc3Cl)C4)ccc2C(C)(C)C1>>CC1(C)CNCc2cc(Nc3ncnc4c3CCN(c3ncccc3Cl)C4)ccc21,,CC#N,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20120214803A1,Nc1cc(F)cc2cccnc12.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=[N+]([O-])c1ccccc1S(=O)(=O)Nc1cc(F)cc2cccnc12,,c1ccncc1,,,,test
US20100137587A1,CCOC(=O)c1nc2ccccn2c1CO.O=S(Cl)Cl>>CCOC(=O)c1nc2ccccn2c1CCl.Cl,,ClC(Cl)Cl,,,,test
US20070219235A1,CC(C)(C)OC(=O)Nc1ccccc1C1CCCCC1>>Nc1ccccc1C1CCCCC1,,C1COCCO1,,Cl,,test
US20070105904A1,Nc1ccccc1.O=Cc1ccc(C2OCCO2)cc1>>c1ccc(NCc2ccc(C3OCCO3)cc2)cc1,,C1CCOC1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20060030595A1,CSc1nccc(I)n1.N#Cc1cccc(C=O)c1>>CSc1nccc(C(O)c2cccc(C#N)c2)n1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20100016293A1,CN1CCNCC1.Clc1ccc2nc(Cl)cnc2c1>>CN1CCN(c2cnc3cc(Cl)ccc3n2)CC1,,O,,,,test
US04363912,C=C(C)C(=O)[O-].CO.c1cncc(Cc2c(C3CC3)[nH]c3ccccc23)c1>>COC(=O)CCn1c(C2CC2)c(Cc2cccnc2)c2ccccc21,,C1CCOC1,,,,test
US20010039285A1,CCOC(=O)Cl.c1ccc(COc2ccc3c(c2)CCNC3c2ccc(OCCN3CCCC3)cc2)cc1>>CCOC(=O)N1CCc2cc(OCc3ccccc3)ccc2C1c1ccc(OCCN2CCCC2)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20160002169A1,COCC(C)(C)c1c(F)cc(N)cc1F.COc1ccc2c(c1)CCN(C(=O)OC(C)(C)C)C2C(=O)O>>COCC(C)(C)c1c(F)cc(NC(=O)C2c3ccc(OC)cc3CCN2C(=O)OC(C)(C)C)cc1F,CN(C)c1ccncc1,CCOC(C)=O,O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US04620865,CCOC(=O)c1cnn(-c2cccc(Cl)c2)c1Cl>>O=C(O)c1cnn(-c2cccc(Cl)c2)c1Cl,,CCO,,Cl,[K+].[OH-],test
US20120149657A1,COc1ccc(CC(OC(c2ccccc2)c2ccccc2)[C@]2(COC(=O)c3ccccc3)O[C@@H](OC)[C@@H](F)[C@@H]2OC(=O)c2ccccc2)cc1>>CO[C@@H]1O[C@](CO)(COC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)[C@@H]1F,,CC(=O)O,O,,,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4ccccc4)nc(Cl)c3n2)cc1.Nc1ccc2[nH]ncc2c1>>c1ccc(-c2nc(Nc3ccc4[nH]ncc4c3)c3[nH]ncc3n2)cc1,C1COCCO1,CO,,Cl,,test
US20100216810A1,CC(C)(C#N)c1cccc(C(=O)O)c1Cl.O=C(Cl)C(=O)Cl>>CC(C)(C#N)c1cccc(C(=O)Cl)c1Cl,,C1CCOC1,,CN(C)C=O,,test
US20070015743A1,O=C(O)CO.Oc1ccc(Nc2ncnc3cccc(OCC4CCNCC4)c23)cc1Cl>>O=C(CO)N1CCC(COc2cccc3ncnc(Nc4ccc(O)c(Cl)c4)c23)CC1,,CC(=O)N(C)C,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US04840869,N#CCCl.O=C(O)c1cc2ccccc2o1>>N#CCOC(=O)c1cc2ccccc2o1,,CCOC(C)=O,,CCN(CC)CC,,test
US07612075B2,CC(=Cc1ccccc1)C(=O)Nc1cccc(Cl)c1>>Cc1cc2ccc(Cl)cc2[nH]c1=O,,Clc1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20130252937A1,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(OCC6CCOC6)cc5C)ccc(F)c43)ccc21>>Cc1cc(OCC2CCOC2)cc(C)c1-c1ccc(F)c2c1CC[C@H]2Oc1ccc2c(c1)OC[C@H]2CC(=O)O,,CC(C)O,,,,test
US20110218177A1,CN(C)c1cccc2cccc(N(C)C)c12.COc1cc(F)c(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CN(C(=O)OC(C)(C)C)[C@@H](C)[C@H](O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.ClCCl.O.O=C(Cl)OCCl>>CCCOC(=O)OCCl,,ClCCl,O,,,test
US20100210696A1,CCOC(=O)c1cc(N)n(-c2ccccc2)n1.O=C(Cl)c1ccccc1>>CCOC(=O)c1cc(NC(=O)c2ccccc2)n(-c2ccccc2)n1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,O,test
US20030105074A1,F.O=C(OCc1ccccc1)N1CCC2(CC1)CO2>>O=C(OCc1ccccc1)N1CCC(O)(CF)CC1,,ClCCl,,[K],,test
US06617325B1,COC(=O)CC(C)(CCCCBr)c1ccccc1.O=C(NC1CCNCC1)c1ccccc1-c1ccc(C(F)(F)F)cc1>>COC(=O)CC(C)(CCCCN1CCC(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)CC1)c1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04855301,COc1ccc(CSC2=NC(C)=C(C(=O)OC(C)C)C(c3cccc([N+](=O)[O-])c3)N2C(=O)N(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CC1=C(C(=O)OC(C)C)C(c2cccc([N+](=O)[O-])c2)N(C(=O)N(C)C)C(=O)N1,,CCOC(C)=O,ClCCl,,,test
US20130096118A1,Cc1c(NC(=O)OCc2ccccc2)cccc1C(C[N+](=O)[O-])c1c[nH]c2ccc(N3CCOCC3)cc12>>Cc1c(NC(=O)OCc2ccccc2)cccc1C(CN)c1c[nH]c2ccc(N3CCOCC3)cc12,[Zn],C1CCOC1,CO,[Cl-].[NH4+],,test
US20150266824A1,C[Si](C)(C)C#N.O=Cc1c(Cl)cccc1[N+](=O)[O-]>>C[Si](C)(C)OC(C#N)c1c(Cl)cccc1[N+](=O)[O-],,ClCCl,,C[N+]1([O-])CCOCC1,,test
US20080188528A1,CC(C)(C)OC(=O)[C@H](CCCN)NC(=O)c1cccn(C(c2ccccc2)c2ccccc2)c1=O.CC(C)N=C=NC(C)C>>CC(C)NC(=NCCC[C@H](NC(=O)c1cccn(C(c2ccccc2)c2ccccc2)c1=O)C(=O)OC(C)(C)C)NC(C)C,,CC(C)O,,,,test
US20140243317A1,CN1c2ccccc2C(Cl)c2ccc(Cl)cc2S1(=O)=O.NCCO>>CN1c2ccccc2C(NCCO)c2ccc(Cl)cc2S1(=O)=O,,CCO,,,,test
US20130178460A1,Cl.Cn1cnc2c(NC(=O)c3csc4cnc(N[C@@H]5CCOC[C@@H]5NC(=O)OC(C)(C)C)nc34)cccc21>>Cl.Cn1cnc2c(NC(=O)c3csc4cnc(N[C@@H]5CCOC[C@@H]5N)nc34)cccc21,,C1COCCO1,,,,test
US04079179,CS[C@]12SCC(COC(C)=O)=C(C(=O)O)N1C(=O)C2N.O=C(Cl)Cc1cccs1>>CS[C@]12SCC(COC(C)=O)=C(C(=O)O)N1C(=O)C2NC(=O)Cc1cccs1,,CC(C)=O,O,O=C([O-])O.[Na+],,test
US05516783,COS(=O)(=O)OC.O=S(=O)(NCc1cc(CBr)cs1)c1ccccc1>>CN(Cc1cc(CBr)cs1)S(=O)(=O)c1ccccc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030087874A1,CCOC(CCNC(=O)[C@H](CC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1)OCC>>O=CCCNC(=O)[C@H](CC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1,,C1CCOC1,,Cl,,test
US20050143377A1,Cc1cc2ccccc2c(CCl)n1.O=C(OO)c1cccc(Cl)c1>>Cc1cc2ccccc2c(CCl)[n+]1[O-],,ClCCl,,,,test
US06329381B1,COCCl.Nc1nc(S)nc2c1nc(O)n2Cc1ccccc1>>COCSc1nc(N)c2nc(O)n(Cc3ccccc3)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140206663A1,CC1C(=O)NN=C2COc3cc(C(F)(F)F)c(CC4CN(C(=O)OC(C)(C)C)C4)cc3N21.O=C(O)C(F)(F)F>>CC1C(=O)NN=C2COc3cc(C(F)(F)F)c(CC4CNC4)cc3N21.O=C(O)C(F)(F)F,,ClCCl,,,,test
US05057513,C1CCC(N2CCCC2)CC1.ClCc1ccccc1.O>>O=C1CCCCC1Cc1ccccc1,,C1COCCO1,,,,test
US20110306604A1,COC(=O)C1(NCC[C@H](NCc2cnc3cc4c(cc3c2)C[C@@]2(C4)C(=O)Nc3ncccc32)c2ccccc2)CCCC1.C[Si](C)(C)O[K]>>O=C([O-])C1(NCC[C@H](NCc2cnc3cc4c(cc3c2)C[C@@]2(C4)C(=O)Nc3ncccc32)c2ccccc2)CCCC1.[K+],,C1CCOC1,,,,test
US20130252937A1,COCC(C)(C)COS(C)(=O)=O.Cc1cc(O)cc(C)c1Br>>COCC(C)(C)COc1cc(C)c(Br)c(C)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06339089B2,C=CCNc1nc(Cl)nc2ccc([N+](=O)[O-])cc12.CC(C)=CCN>>C=CCNc1nc(NCC=C(C)C)nc2ccc([N+](=O)[O-])cc12,,CC#N,,CCN(CC)CC,Cl,test
US20150252032A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N#Cc1c[nH]c2ncccc12>>CC(C)(C)OC(=O)n1cc(C#N)c2cccnc21,,CN(C)C=O,,[H-].[Na+],,test
US20100303928A1,CCOC(=O)c1nc(Br)c2onc(-c3ccccc3)c2c1O.OB(O)c1ccccc1>>CCOC(=O)c1nc(-c2ccccc2)c2onc(-c3ccccc3)c2c1O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090105258A1,CC(C)(C)c1ccc(C=O)cc1.O=C(O)Cc1ccccc1>>CC(C)(C)c1ccc(C=C(C(=O)O)c2ccccc2)cc1,,Cl,,CC(=O)OC(C)=O,,test
US20110201663A1,CC(C)=O.CCCBr.CCOC(=O)c1c(C(=O)OCC)c(O)c2ccccc2c1O.Cc1ccccc1>>CCCOc1c(C(=O)OCC)c(C(=O)OCC)c(OCCC)c2ccccc12,,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20120230951A1,COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1)C(C)C.Clc1cnc2cc(Br)ccc2n1>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc(-c3cnc4cc(Br)ccc4n3)cc2)[nH]1)C(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US05637770,O=C(O)CCCc1ccccc1F>>O=C1CCCc2c(F)cccc21,,O,,,,test
US20110009394A1,CC(C)(C)OC(=O)NC1CCNCC1.COc1ccc2ncc(=O)n(CCC3CO3)c2n1>>COc1ccc2ncc(=O)n(CCC(O)CN3CCC(NC(=O)OC(C)(C)C)CC3)c2n1,,CN(C)C=O,,,,test
US20050239817A1,CCCCOc1ccc(C2=NC3CCC(OC(C)=O)CC3c3cc(OC)c(OC)cc32)cc1>>CCCCOc1ccc(C2=NC3CCC(O)CC3c3cc(OC)c(OC)cc32)cc1,,CO,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130150341A1,CC(C)(C)OC(=O)N1CCc2nc(NC(=O)Oc3ccccc3)sc2C1.CN>>CNC(=O)Nc1nc2c(s1)CN(C(=O)OC(C)(C)C)CC2,,CN(C)C=O,O,,,test
US04327213,CO/N=C(\C#N)c1cnccn1.OO>>CO/N=C(\C#N)c1c[n+]([O-])ccn1,,O,,CC(=O)O,,test
US20070213323A1,Clc1ccc(CBr)cc1.O=c1cnc(Br)c[nH]1>>O=c1cnc(Br)cn1Cc1ccc(Cl)cc1,,CC#N,,,,test
US20100311754A1,C1COCCN1.CS(=O)(=O)c1nccc(Oc2ccc(NC(=O)c3cc(F)cc(N4CCOCC4)c3)c3ccccc23)n1>>O=C(Nc1ccc(Oc2ccnc(N3CCOCC3)n2)c2ccccc12)c1cc(F)cc(N2CCOCC2)c1,,CS(C)=O,ClCCl,,,test
US20040102437A1,Nc1ccc2[nH]ncc2c1.O=C=Nc1c(Cl)cccc1Cl>>O=C(Nc1ccc2[nH]ncc2c1)Nc1c(Cl)cccc1Cl,,Cc1ccccc1,,,,test
US04088652,CC(=O)OC(C)=O.c1ccc(C23CNCC2C3)cc1>>CC(=O)N1CC2CC2(c2ccccc2)C1,,CCOCC,ClCCl,c1ccncc1,,test
US20040192943A1,Nc1cc(-c2ccc(F)cc2)sc1S(N)(=O)=O.O=C=NS(=O)(=O)Cl>>NC(=O)Nc1cc(-c2ccc(F)cc2)sc1S(N)(=O)=O,,ClCCl,,O,,test
US04663344,CC(=O)Oc1c(C)sc2ccccc12.O=C1CCC(=O)N1Br>>CC(=O)Oc1c(CBr)sc2ccccc12,O=C(OOC(=O)c1ccccc1)c1ccccc1,,,,,test
US20080213297A1,NNC(=O)CCCCC(=O)NN.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>NNC(=O)CCCCC(=O)NNC1OC(CO)C(O)C(O)C1O,,CC#N,O,,,test
US05599954,CCOC(=O)C[C@@H](CCNC(=O)OCc1ccccc1)OC1CCCCO1>>O=C(O)C[C@@H](CCNC(=O)OCc1ccccc1)OC1CCCCO1,,O,,CO,[Na+].[OH-],test
US20130109566A1,C#CCN(C(=O)OC(C)(C)C)c1cn(-c2cncc(F)c2)nc1C.Cl>>C#CCNc1cn(-c2cncc(F)c2)nc1C.Cl,,C1COCCO1,CCOCC,,,test
US20130059830A1,CC(C)(C)OC(=O)N1CC(c2cc(-c3ccc(Cl)cc3)nn2-c2ncccn2)OCC1CCc1ccccc1>>Clc1ccc(-c2cc(C3CNC(CCc4ccccc4)CO3)n(-c3ncccn3)n2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06262040B1,CCc1nn(C2CCCC2)c2cc(C(=O)Cl)ccc12.COc1cccc(N)c1>>CCc1nn(C2CCCC2)c2cc(C(=O)Nc3cccc(OC)c3)ccc12,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US05604242,CCOC(=O)C1CCCN(CCOCCCc2ccccc2)C1.Cl>>Cl.O=C(O)C1CCCN(CCOCCCc2ccccc2)C1,,CCO,,ClCCl,[Na+].[OH-],test
US20090192162A1,CCOC(=O)COc1ccc(Sc2cc(C#CCN3CCOCC3)cc(OCc3ccc(F)cc3)c2)cc1C>>Cc1cc(Sc2cc(C#CCN3CCOCC3)cc(OCc3ccc(F)cc3)c2)ccc1OCC(=O)O,,CCO,,Cl,[Na+].[OH-],test
US20120149686A1,CC(C)(C)OC(=O)N1CCN(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.COc1ccc2c(c1)[C@]1(C[C@H]1c1ccc3c(I)n[nH]c3c1)C(=O)N2C.O=C(O)C(F)(F)F>>COc1ccc2c(c1)[C@]1(C[C@H]1c1ccc3c(-c4ccc(N5CCNCC5)cc4)n[nH]c3c1)C(=O)N2C.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20020132949A1,O=C(O)/C=C\C(=O)O.[Fe]>>O=C([O-])/C=C\C(=O)[O-].[Fe+2],,O,,,,test
US20040034049A1,COc1c(C)c(C)c(OC)c(Br)c1C.O=CC1CCN(Cc2ccccc2)CC1>>COc1c(C)c(C)c(OC)c(C(O)C2CCN(Cc3ccccc3)CC2)c1C,,C1CCOC1,,O,[Li]CCCC,test
US20080181866A1,O=C(Cl)OCc1ccccc1.O=C(O)C1CS[C@H](c2cncs2)N1>>O=C(O)C1CS[C@H](c2cncs2)N1C(=O)OCc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20130252944A1,CCCC1Cc2sc(Nc3nccc(C)n3)nc2-c2cn(Cc3ccc(OC)cc3)nc21>>CCCC1Cc2sc(Nc3nccc(C)n3)nc2-c2cn[nH]c21,,O=C(O)C(F)(F)F,,,,test
US06057349,CN(C)S(=O)(=O)N1CCN=C1[Si](C)(C)C(C)(C)C.Cc1ccc(CBr)cc1[N+](=O)[O-]>>Cc1ccc(Cc2cnc([Si](C)(C)C(C)(C)C)n2S(=O)(=O)N(C)C)cc1[N+](=O)[O-],,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US05717049,C=CC(=O)Cl.NCCc1ccccc1>>C=CC(=O)N(C)Cc1ccccc1,,CCOCC,,CCN(CC)CC,,test
US20060189606A1,CC(=O)N1CCc2ccc(I)cc21>>Ic1ccc2c(c1)NCC2,,O,,CCO,[Na+].[OH-],test
US04262013,BrBr.CCOC(=O)CC(C)(O)C=CCCc1ccc(OCc2ccc(F)cc2)cc1>>CC1(O)CC(=O)OC(CCc2ccc(OCc3ccc(F)cc3)cc2)C1Br,,CO,,[Na+].[OH-],,test
US20120115850A1,CC(C)(C)OC(=O)N1CCNCC1.COc1cc(OC)cc(C(C)Nc2cc(F)ccc2C(=O)C(F)(F)F)c1>>COc1cc(OC)cc(C(C)Nc2cc(N3CCN(C(=O)OC(C)(C)C)CC3)ccc2C(=O)C(F)(F)F)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US06326501B1,COC(=O)OC.COC(=O)c1c[nH]c2ccccc12>>COC(=O)c1cn(C)c2ccccc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06498165B1,C[C@H](Nc1nccc(-n2cnc3ccc(I)cc32)n1)c1ccccc1.OB(O)c1cccc2ccccc12>>C[C@H](Nc1nccc(-n2cnc3ccc(-c4cccc5ccccc45)cc32)n1)c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCCO,,O,O=C([O-])[O-].[K+].[K+],test
US20080214448A1,COC(=O)CCCCc1noc(-c2ccccc2OC)n1>>COC(=O)CCCCc1noc(-c2ccccc2O)n1,,ClCCl,,BrB(Br)Br,CO,test
US20120225867A1,CCOC(=O)C(=O)NCC(=O)OC.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CCOC(=O)c1ncc(OC)s1,,ClC(Cl)Cl,,ClCCl,,test
US20140371201A1,COc1cc(Br)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21.OB(O)c1cccc(C(F)(F)F)c1>>COc1cc(-c2cccc(C(F)(F)F)c2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US06197729B1,C=CC(F)(F)F.Ic1ccc(OCc2ccccc2)cc1>>FC(F)(F)C=Cc1ccc(OCc2ccccc2)cc1,Cl[Pd]Cl,CO,,O,CC(=O)[O-].[K+],test
US20010003749A1,CCOC(CC(C)(C(=O)C1CCCCC1)c1ccccc1)OCC>>CC(CC=O)(C(=O)C1CCCCC1)c1ccccc1,,CC(C)=O,,Cl,,test
US20100063038A1,BrC(Br)(Br)Br.Nc1ncnn2c(CCCO)cc(Br)c12>>Nc1ncnn2c(CCCBr)cc(Br)c12,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US05324870,O=C(CCO)Cc1ccccc1>>OCCC(O)Cc1ccccc1,,CO,,,,test
US20130079329A1,O=C(Nc1ccc(C(F)(F)F)nc1)c1nn(C2CCCCO2)c2ccc(-c3cncc(F)c3)cc12>>O=C(Nc1ccc(C(F)(F)F)nc1)c1n[nH]c2ccc(-c3cncc(F)c3)cc12,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20060100229A1,CCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)N.O=C(Cl)c1cccnc1>>CCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)NC(=O)c1cccnc1,,ClCCl,,CCN(CC)CC,Cl,test
US20160084845A1,NCCS(=O)O.O=C(O)c1ccccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12.O=C(ON1C(=O)CCC1=O)c1ccccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12>>O=C(NCCS(=O)O)c1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1,,C1CCOC1,,[Na+].[OH-],,test
US20090099155A1,Cc1cc(CN)ccc1C(=O)NC1CCCCCC1.O=C(N1CCc2ccc(Cl)c(OS(=O)(=O)C(F)(F)F)c2CC1)C(F)(F)F>>Cc1cc(CNc2c(Cl)ccc3c2CCN(C(=O)C(F)(F)F)CC3)ccc1C(=O)NC1CCCCCC1,,Cc1ccccc1,,,,test
US20120232056A1,COC(=O)c1ccc2nc(-c3cncc(Br)c3)c(N(C)C(C)C)nc2c1>>CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1cncc(Br)c1,,CO,,O,[Na+].[OH-],test
US20150105404A1,Clc1cccc([Mg]Br)c1.O=c1[nH]c2ccc(Br)cc2c(O)c1-c1cccc(C(F)(F)F)c1>>O=C(c1ccc(C(F)(F)F)nc1)c1cccc(Cl)c1,,C1CCOC1,,,,test
US20020032187A1,CNc1cccc(CCOc2ccc3c(c2)CN(CCc2ccccc2)C(=O)[C@H](CC(=O)OC)C3)n1>>CNc1cccc(CCOc2ccc3c(c2)CN(CCc2ccccc2)C(=O)[C@H](CC(=O)O)C3)n1,,C1CCOC1,O,[Li+].[OH-],,test
US04638008,CCOC(=O)Cl.CN(C)CCCn1c2c(c3c(N)cccc31)CCCCCC2>>CCOC(=O)Nc1cccc2c1c1c(n2CCCN(C)C)CCCCCC1,,CC#N,CCOCC,CCN(CC)CC,,test
US20100041719A1,CC(C)(C)C(=O)N1N=C(c2cc(F)ccc2F)SC1(CCCN)c1ccccc1.CN.N#CN=C(Oc1ccccc1)Oc1ccccc1>>CN/C(=N/C#N)NCCCC1(c2ccccc2)SC(c2cc(F)ccc2F)=NN1C(=O)C(C)(C)C,,CC(C)O,CO,CCN(CC)CC,,test
US20070244132A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC#CCCl>>CC(C)(C)OC(=O)NCC#CCCl,,CO,O,Cl,[Na+].[OH-],test
US20100129800A1,CC(O)C(CO)NC(=O)c1c2ccccc2nc2ccccc12.COC1(OC)C=CC(C(Cl)(c2ccccc2)c2ccccc2)=CC1>>COc1ccc(C(OCC(NC(=O)c2c3ccccc3nc3ccccc23)C(C)O)(c2ccccc2)c2ccc(OC)cc2)cc1,,c1ccncc1,,CO,,test
US06441017B1,COc1cccc(-c2ccccc2[N+](=O)[O-])c1>>O=[N+]([O-])c1ccccc1-c1cccc(O)c1,,ClCCl,,BrB(Br)Br,,test
US20140314669A1,CC(C)(C)OC(=O)C[C@H](NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1cncc(CCc2ccc(O)cc2)c1.Cc1ccc(S(=O)(=O)OCCOS(=O)(=O)c2ccc(C)cc2)cc1>>Cc1ccc(S(=O)(=O)OCCOc2ccc(CCc3cncc([C@H](CC(=O)OC(C)(C)C)NC(=O)[C@@H]4CCCN(C(=O)CCC5CCN(C(=O)OC(C)(C)C)CC5)C4)c3)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US03995052,CC(=O)CCNC=O.OCCC1=CCc2ccccc21>>CC1(CCNC=O)OCCC2=C1Cc1ccccc12,,c1ccccc1,,FB(F)F,,test
US06723716B1,CC(=O)SCc1nc(C)sc1SC(C)=O.O=S(=O)(CCI)c1ccccc1>>CC(=O)SCc1nc(C)sc1SCCS(=O)(=O)c1ccccc1,,CO,,C[O-].[Na+],,test
US20100105906A1,O=C(c1cccnc1Oc1cc(Cl)ccc1Cl)N1CCNc2ccccc21.c1ccc2c(c1)NCc1cccn1-2>>O=C(c1cccnc1Oc1cc(Cl)ccc1Cl)N1CC2CCCN2c2ccccc21,[Pd],CCO,,CCN(C(C)C)C(C)C,,test
US05102893,C=CC(=O)OCC.CC(C)c1nn(-c2ccc3ccccc3n2)c(-c2ccc(F)cc2)c1Br>>CCOC(=O)/C=C/c1c(C(C)C)nn(-c2ccc3ccccc3n2)c1-c1ccc(F)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20010039348A1,CNC.COc1cc(OS(=O)(=O)C(F)(F)F)c([N+](=O)[O-])cc1Cl>>COc1cc(N(C)C)c([N+](=O)[O-])cc1Cl,,C1CCOC1,,,,test
US20120010191A1,O=[N+]([O-])c1ccc(N2CCN(CCF)CC2)cn1>>Nc1ccc(N2CCN(CCF)CC2)cn1,,CCO,,,,test
US20050085638A1,Nc1nc(Cl)c2ncn([C@H]3CO[C@@H](COC(=O)c4ccccc4)O3)c2n1>>Nc1nc(Cl)c2ncn([C@H]3CO[C@@H](CO)O3)c2n1,,CO,,CO[Na],,test
US20150141400A1,CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(C=O)c(C(F)(F)F)cc2c1=O.FC(F)CN1CCNCC1>>CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(CN3CCN(CC(F)F)CC3)c(C(F)(F)F)cc2c1=O,,ClCCl,,,,test
US20120214767A1,C=Cc1ccc2c(c1)CCC1C2=NOC1(O)c1onc(-c2ccccn2)c1C(F)(F)F>>C=Cc1ccc2c(c1)CCc1c-2noc1-c1onc(-c2ccccn2)c1C(F)(F)F,,Cc1ccccc1,,O=S(Cl)Cl,c1ccncc1,test
US20070037807A1,Cc1ccc(-c2c(CN)c(CC(C)(C)C)nc(C)c2C(=O)O)cc1.O=C(O)C(O)C(O)C(=O)O>>Cc1ccc(-c2c(CN)c(CC(C)(C)C)nc(C)c2C(=O)O)cc1.O=C(O)C(O)C(O)C(=O)O,,CC#N,,O,,test
US20140200197A1,C#C[C@@H]1CN(C(=O)OC(C)(C)C)[C@H](CO)CO1.NCC(F)(F)F.O=C(n1ccnc1)n1ccnc1>>C#C[C@@H]1CN(C(=O)OC(C)(C)C)[C@@H](COC(=O)NCC(F)(F)F)CO1,,c1ccncc1,,,,test
US05130318,CCN=C=O.Cc1cc(OCc2ccc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc2)c(CN)c(C)n1>>CCNC(=O)NCc1c(OCc2ccc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc2)cc(C)nc1C,,ClCCl,,,,test
US04820730,CS(=O)(=O)O.CS(=O)(=O)Oc1ccc2cc(C(=N)N)ccc2c1.O=C(O)c1ccc(NN2C=NCC2)cc1>>CS(=O)(=O)O.CS(=O)(=O)O.N=C(N)c1ccc2cc(OC(=O)c3ccc(NN4C=NCC4)cc3)ccc2c1,CN(C)c1ccncc1,c1ccncc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20130225620A1,Cn1ccc2cc(C#N)ccc21>>Cn1ccc2cc(CN)ccc21,[Ni],CO,N,,,test
US20140243302A1,COc1cc(F)c2ncc(F)c(CCC34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2c1.Cl>>COc1cc(F)c2ncc(F)c(CCC34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2c1.Cl,,CCO,ClCCl,,,test
US20150210688A1,CI.C[Si](C)(C)CCOCn1cc(O)cn1>>COc1cnn(COCC[Si](C)(C)C)c1,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120225869A1,COc1ccc(CNc2nccc(-c3ccc(-c4nc5c(c(S(C)(=O)=O)nn5-c5ccccc5)c(=O)n4-c4ccc(Cl)cc4)cc3)n2)cc1>>CS(=O)(=O)c1nn(-c2ccccc2)c2nc(-c3ccc(-c4ccnc(N)n4)cc3)n(-c3ccc(Cl)cc3)c(=O)c12,,O=C(O)C(F)(F)F,,,,test
US04831041,Cc1cccc(NC(N)=O)c1CO.O=S(Cl)Cl>>Cc1cccc(NC(N)=O)c1CCl,,ClCCl,,,,test
US20070254873A1,NC(=O)c1cc(-c2ccc(CO)s2)cc2c(C3CCN(S(=O)(=O)CCCN4CCOCC4)CC3)c[nH]c12>>NC(=O)c1cc(-c2ccc(C=O)s2)cc2c(C3CCN(S(=O)(=O)CCCN4CCOCC4)CC3)c[nH]c12,O=[Mn]=O,C1CCOC1,,,,test
US20150111877A1,CC(=O)OC(C)=O.Cc1cccc(S(=O)(=O)N2C[C@H](CN)Oc3ncc(N)cc32)c1>>CC(=O)NC[C@H]1CN(S(=O)(=O)c2cccc(C)c2)c2cc(N)cnc2O1,,C1CCOC1,,,,test
US20060106075A1,CC(C)C(=O)c1ccc(CCNC(=O)C(F)(F)F)cc1>>CC(C)Cc1ccc(CCNC(=O)C(F)(F)F)cc1,[Pd],CCO,Cl,[H][H],,test
US20070135477A1,COc1cc2nc(-c3n[nH]cc3N)[nH]c2cc1OC.O=C=Nc1ccc(F)cc1F>>COc1cc2nc(-c3n[nH]cc3NC(=O)Nc3c(F)cccc3F)[nH]c2cc1OC,,CCO,,CCN(CC)CC,CN(C)C=O,test
US04581168,COC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)OC(C)(C)C>>COC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCC(N)=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120264748A1,BrCc1cccc2c1OCCO2.O=C1NCCCC12CCN(c1cnc3ccccc3n1)CC2>>O=C1N(Cc2cccc3c2OCCO3)CCCC12CCN(c1cnc3ccccc3n1)CC2,,[Cl-],[NH4+],C1CCOC1,,test
US04517202,C1CC2CCCC2C1.CO>>OC1CCC2CCCC12,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20080146612A1,CCOC(=O)C1(C#N)CCCCCC1>>NCC1(CO)CCCCCC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150225375A1,COCC1(CN[C@@H]2C[C@H]2c2ccccc2)CCN(C(=O)OC(C)(C)C)CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COCC1(CN(C(=O)C(F)(F)F)[C@@H]2C[C@H]2c2ccccc2)CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04315014,CC(=O)Nc1ccc(-c2ccc(C#N)c(=O)[nH]2)cc1.[OH-]>>Nc1ccc(-c2ccc(C(=O)O)c(=O)[nH]2)cc1,,Cl,,O,,test
US20100113462A1,CCOC(=O)C1(N)Cc2ccccc2C1.O=C(O)[C@H]1CCCc2ccccc21>>CCOC(=O)C1(NC(=O)[C@H]2CCCc3ccccc32)Cc2ccccc2C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100280268A1,COC(=O)c1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(OCc3ccccc3)c2)ccc1NS(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)Nc2ccc(Oc3ccc(NS(=O)(=O)c4ccc(C)cc4)c(C(=O)O)c3)cc2OCc2ccccc2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US04238505,Cc1c(Cl)ccc(-c2ccccc2)c1Cl.O=C1CCC(=O)N1Br>>Clc1ccc(-c2ccccc2)c(Cl)c1CBr,,ClC(Cl)(Cl)Cl,,,,test
US20150189880A1,CCS.O=C(Nc1ccc(C(F)(F)F)cn1)c1ncc(C(F)(F)F)cc1Cl>>CCSc1cc(C(F)(F)F)cnc1C(=O)Nc1ccc(C(F)(F)F)cn1,,O,,CN(C)C=O,[H-].[Na+],test
US20020028835A1,[N-]=[N+]=NC[C@H](O)c1ccc(OCc2ccccc2)c(NS(=O)(=O)c2ccccc2)c1>>NC[C@H](O)c1ccc(O)c(NS(=O)(=O)c2ccccc2)c1,[Pd],CCO,,,,test
US20120258925A1,C=C[C@@H](OCc1ccccc1)[C@H](F)CN=[N+]=[N-].CC(=O)O>>[N-]=[N+]=NC[C@@H](F)[C@H](OCc1ccccc1)C(=O)O,,CC(=O)O,CCOC(C)=O,O,O=C(O)C(F)(F)F,test
US20160046605A1,COc1ccc(C(F)(F)F)c(-c2cnc(N)c(C(=O)Nc3ncccc3N3CCC(C)(NC(=O)OC(C)(C)C)CC3)n2)n1>>COc1ccc(C(F)(F)F)c(-c2cnc(N)c(C(=O)Nc3ncccc3N3CCC(C)(N)CC3)n2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110306589A1,CCOC(=O)c1nc(Cl)ccc1Nc1cncnc1>>O=C(O)c1nc(Cl)ccc1Nc1cncnc1,,C1CCOC1,CCO,Cl,[Li+].[OH-],test
US20070232649A1,COc1ccc(CS(=O)(=O)CC(=O)O)cc1.O=Cc1cc(Br)ccc1O>>COc1ccc(CS(=O)(=O)c2cc3cc(Br)ccc3oc2=O)cc1,,CC(=O)O,,,,test
US20020103229A1,CC(=O)n1nc(-c2ccc(F)cc2)c2cc(C(=O)Cl)ccc21.NCCCN1CCOCC1>>O=C(NCCCN1CCOCC1)c1ccc2[nH]nc(-c3ccc(F)cc3)c2c1,,c1ccncc1,,,,test
US20090253679A1,NCC1CC1.O=C1NC(=S)N/C1=C\c1c[nH]c2ncccc12>>O=C1NC(NCC2CC2)=N/C1=C\c1c[nH]c2ncccc12,,CCO,,,,test
US20160251339A1,COc1ccc(S(=O)(=O)Cl)cc1N1CCN(C(=O)C(Cl)(Cl)Cl)CC1.O=Cc1c[nH]c2cc(Cl)c(Cl)cc12>>COc1ccc(S(=O)(=O)n2cc(C=O)c3cc(Cl)c(Cl)cc32)cc1N1CCN(C(=O)C(Cl)(Cl)Cl)CC1,,C1CCOC1,,[H-].[Na+],,test
US20120165343A1,COC(=O)c1ccc(C(O)CC(C)C)nc1.Oc1ccc(-c2ccc(C(F)(F)F)cc2)cc1>>COC(=O)c1ccc(C(CC(C)C)Oc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)nc1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090105295A1,CC(C)Cn1c(CON)nc2c(N)nc3c(c21)CCCC3.CS(=O)(=O)Cl.ClCCl>>CC(C)Cn1c(CONS(C)(=O)=O)nc2c(N)nc3c(c21)CCCC3.Cl,,ClCCl,,CCN(CC)CC,,test
US20040116690A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C1CC(CCCCCF)CCN1>>CC(C)(C)OC(=O)N1CCC(CCCCCF)CC1C(=O)O,,CC(C)(C)O,,[Na+].[OH-],,test
US20090149425A1,BrC(Br)(Br)Br.OCc1cc(C(F)(F)C(F)(F)F)on1>>FC(F)(F)C(F)(F)c1cc(CBr)no1,,CCOCC,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060264460A1,Cn1cnc(C=O)c1.N#Cc1cnc2c(Br)cc(NCc3ccccn3)cc2c1Nc1ccc(F)c(Cl)c1>>Cn1cnc(CNc2cc(Br)c3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)c1,,C1CCOC1,CO,[BH3-]C#N.[Na+],,test
US04786310,C=CCn1c(=O)sc2cc(F)c(N=C=S)cc21.CCOC(=O)N1CCCCN1>>C=CCn1c(=O)sc2cc(F)c(NC(=S)N3CCCCN3C(=O)OCC)cc21,,O,,CCN(CC)CC,Cc1ccccc1,test
US20160145267A1,CCOc1cc(F)c(Cn2nc(-c3nc(N)c(O)c(N)n3)c(C)c2C2CC2)c(F)c1.COCCBr>>CCOc1cc(F)c(Cn2nc(-c3nc(N)c(OCCOC)c(N)n3)c(C)c2C2CC2)c(F)c1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140275057A1,Nc1ccc(S(=O)(=O)c2cccc(OC(F)(F)F)c2)cc1.O=C(Cl)C=Cc1cccnc1>>O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2cccc(OC(F)(F)F)c2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110263562A1,CC(=O)CO[C@@H]1CC[C@@H](c2cc3ccc(OCC4CC4)cc3o2)CC1>>CC(O)CO[C@@H]1CC[C@@H](c2cc3ccc(OCC4CC4)cc3o2)CC1,,CCO,,[BH4-].[Na+],,test
US20160039825A1,C[Si](C)(C)C=[N+]=[N-].Cl.O=C(O)c1cc2n(n1)CCN(C(=O)OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C2>>O=C(CCl)c1cc2n(n1)CCN(C(=O)OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C2,,O=S(Cl)Cl,,[Na+].[OH-],,test
US20130317001A1,O=C(NS(=O)(=O)N1CCC1)c1cc(Cl)c(F)cc1F.OCC1CCC2(CCC2)CC1>>O=C(NS(=O)(=O)N1CCC1)c1cc(Cl)c(OCC2CCC3(CCC3)CC2)cc1F,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20070185143A1,CCOC(=O)C(=O)C1CCC=C(OCC)C1=O.NN>>CCOC(=O)c1n[nH]c2c1CCC=C2OCC,,CCO,,O,,test
US03998834,CI.O=C(O)C1(Nc2ccccc2)CCN(CCc2ccccc2)CC1>>COC(=O)C1(Nc2ccccc2)CCN(CCc2ccccc2)CC1,,CN(C)P(=O)(N(C)C)N(C)C,,[Na],,test
US20150080393A1,CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4ccc(-c5ccc(OC(C)C)cc5)cc4-c4ccccc4)C(F)(F)F)nc(N)n3)CC2)CN1C(=O)OC(C)(C)C>>CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4ccc(-c5ccc(OC(C)C)cc5)cc4-c4ccccc4)C(F)(F)F)nc(N)n3)CC2)CN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080214598A1,CC(C)(C)[SiH2]OC(C)(C)c1cc(CN)ccc1Cl.O=C(O)CC(F)(F)F>>CC(C)(C)[SiH2]OC(C)(C)c1cc(CNC(=O)CC(F)(F)F)ccc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20050288525A1,C=CC[Si](Cl)(Cl)Cl.CN[C@@H](C)[C@@H](O)c1ccccc1>>C=CC[Si]1(Cl)O[C@@H](c2ccccc2)[C@H](C)N1C,,ClCCl,,CCN(CC)CC,,test
US20150218181A1,CCCC[Sn](CCCC)(CCCC)c1cncs1.Clc1cc2cc(Br)ccc2cn1>>Clc1cc2cc(-c3cncs3)ccc2cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,COCCOC,,,test
US20140275523A1,CC(N)=NNC(C)C.Cc1nc(-c2cn(CCO)c(-c3ccc(Br)cc3F)n2)n(C(C)C)n1>>CC(=NC(=O)c1c[nH]c(-c2ccc(Br)cc2F)n1)NNC(C)C,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20150191482A1,COc1ccc(B(O)O)cn1.Nc1cnc(Br)cn1>>COc1ccc(-c2cnc(N)cn2)cn1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20020161240A1,CC(C)(C)OC(=O)COc1cccc(C(=O)C=Cc2cccnc2)c1>>CC(C)(C)OC(=O)COc1cccc(C(=O)CCc2cccnc2)c1,[Pd],CCOC(C)=O,,,,test
US20100041658A1,CCc1ccc(Oc2ccc(C(C)=O)cc2F)c(O)c1.CON>>CCc1ccc(Oc2ccc(/C(C)=N/OC)cc2F)c(O)c1,,CCO,,CCN(CC)CC,Cl,test
US20150266857A1,C1COCCN1.O=S(=O)(c1ccccc1)n1cc(-c2ccc3[nH]c(CCl)nc3c2)c2ccc(F)cc21>>O=S(=O)(c1ccccc1)n1cc(-c2ccc3[nH]c(CN4CCOCC4)nc3c2)c2ccc(F)cc21,,CCOC(C)=O,CN(C)C=O,,,test
US20150048284A1,CCOC(=O)CBr.NCc1cccc(OCc2ccccc2)c1>>CCOC(=O)CNCc1cccc(OCc2ccccc2)c1,,CC#N,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20080207690A1,CC(C)COc1cccc(F)c1.CN(C)C=O>>CC(C)COc1cccc(F)c1C=O,,C1CCOC1,,[Li]C(C)CC,,test
US20160199372A1,Cc1nc(-c2cccc([N+](=O)[O-])c2)cs1>>Cc1nc(-c2cccc(N)c2)cs1,[Zn],CCO,,[Cl-].[NH4+],,test
US20060287542A1,CCCCCCC(O)CCCCCCCCCCC(=O)OCC.CCCCCCCCCCCCCCCC(=O)Cl>>CCCCCCCCCCCCCCCC(=O)OC(CCCCCC)CCCCCCCCCCC(=O)OCC,,COC(C)(C)C,,O,c1ccncc1,test
US05145868,OCC(Br)C(O)c1ccsc1>>OCC1OC1c1ccsc1,,CCO,O,[Na+].[OH-],,test
US04481142,COS(=O)(=O)OC.Sc1ncc2c(n1)-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2>>CSc1ncc2c(n1)-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2,,O,,CCO,[Na+].[OH-],test
US20160060237A1,CCOC(=O)C=C(C)c1ccc(OCC=Cc2ccccc2)c([N+](=O)[O-])c1>>CCOC(=O)CC(C)c1ccc(OCCCc2ccccc2)c(N)c1,[Pd],C1CCOC1,CCOC(C)=O,,,test
US20110028390A1,CCc1n[nH]c2ccc(Br)cc12.O=C=O>>CCc1n[nH]c2ccc(C(=O)O)cc12,,CCOCC,,[Li]C(C)(C)C,,test
US06072074,CCOC(=O)CC(C)(C)C(Cl)CC(C)(Cl)Cl>>CC#C[C@H]1[C@H](C(=O)OCC)C1(C)C,,CCO,,C,C[O-].[Na+],test
US20070167452A1,COC(=O)[C@@H]1CC[C@H](C(=O)NCc2ccccc2)CC1>>OC[C@H]1CC[C@@H](CNCc2ccccc2)CC1,,C1CCOC1,ClCCl,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06458830B1,BrCc1ccccc1.CCCCOC(=O)N1CCC(C(=O)O)CC1>>CCCCOC(=O)N1CCC(C(=O)OCc2ccccc2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160176864A1,CC(C)(C)[Si](C)(C)OC1(c2ccc(Br)cc2)COC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(c2ccc(C3(O[Si](C)(C)C(C)(C)C)COC3)cc2)OC1(C)C,,C1CCOC1,,[Li]CCCC,,test
US20120208874A1,C#CCBr.Oc1ccc2c(c1)OCO2>>C#CCOc1ccc2c(c1)OCO2,,Cc1ccccc1,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20070111984A1,CC(C)C#N.ClCCOCCl>>CC(C)(C#N)COCCCl,,C1CCOC1,CCOCC,O,CC(C)[N-]C(C)C.[Li+],test
US20160068512A1,CC(=O)O.NCCOc1nc(NCc2ccc(C(F)(F)F)cc2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2n1>>CC(=O)NCCOc1nc(NCc2ccc(C(F)(F)F)cc2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04301235,CCCCCCCCCCCCCC(=O)Cl.Cc1nn(C2C(=O)N(c3c(Cl)cc(Cl)cc3Cl)N=C2Nc2ccccc2)cc1N>>CCCCCCCCCCCCCC(=O)Nc1cn(C2C(=O)N(c3c(Cl)cc(Cl)cc3Cl)N=C2Nc2ccccc2)nc1C,,CC#N,,CCOC(C)=O,,test
US20130085141A1,CC(C)(C)OC(=O)N1CCN2C[C@H](Oc3cnc(C4(C)CC4)cn3)C[C@H]2C1.O=S(=O)(Cl)c1cccc(C(F)(F)F)c1>>CC1(c2cnc(O[C@@H]3C[C@H]4CN(S(=O)(=O)c5cccc(C(F)(F)F)c5)CCN4C3)cn2)CC1,,C1COCCO1,ClCCl,CCN(C(C)C)C(C)C,Cl,test
US20030207875A1,CCCCI.COc1nc(N)c(Cl)cc1C(=O)CCC1CCNCC1>>CCCCN1CCC(CCC(=O)c2cc(Cl)c(N)nc2OC)CC1,,C1CCOC1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20090181965A1,COc1cc(NC(N)=S)ccc1-c1cnc(C)s1.O=C1C(Br)CCCC1c1ccccc1>>COc1cc(Nc2nc3c(s2)CCCC3c2ccccc2)ccc1-c1cnc(C)s1,,CCO,,,,test
US20160115128A1,Clc1ncccn1.NCC(F)(F)C(F)(F)F>>FC(F)(F)C(F)(F)CNc1ncccn1,,O,,CCN(C(C)C)C(C)C,,test
US20130225620A1,C[C@H](N)c1ccc2c(c1)ncn2C1CCCCO1.Clc1ncc(Cl)c(Nc2cc(C3CC3)[nH]n2)n1>>C[C@H](Nc1ncc(Cl)c(Nc2cc(C3CC3)[nH]n2)n1)c1ccc2[nH]cnc2c1,,CCCCO,,CCN(C(C)C)C(C)C,Cl,test
US20070129371A1,COC(=O)C(=O)Cl.Nc1ccc(Cl)cc1>>COC(=O)C(=O)Nc1ccc(Cl)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20120258953A1,O=C1CCN(C(=O)OCc2ccccc2)C(c2ccc(F)cc2)C1>>O=C1CCNC(c2ccc(F)cc2)C1,[Pd],C1CCOC1,CCOC(C)=O,,,test
US06518257B1,CC(=O)OC(C)=O.COc1ccc([N+](=O)[O-])cc1Br>>COc1ccc(NC(C)=O)cc1Br,[Fe],,,,,test
US20020099047A1,COc1ccc(CCOS(=O)(=O)c2ccc(C)cc2)cc1.OC[C@H]1CCCCN1>>COc1ccc(CCN2CCCC[C@@H]2CO)cc1,,CC#N,,[I-].[Na+],,test
US04092311,Clc1ccc(-c2ccc(Cl)nn2)cc1.NNCCO>>NN(CCO)c1ccc(-c2ccc(Cl)cc2)nn1,,CCCCO,,,,test
US04349552,CC(=O)CCN=C=O.O=c1[nH]cc(F)c(=O)[nH]1>>CC(=O)CCNC(=O)n1cc(F)c(=O)[nH]c1=O,,CC(=O)N(C)C,CCOC(C)=O,,,test
US07071201B2,NCCN1CCC(N2CCc3ccccc32)CC1.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=S(=O)(NCCN1CCC(N2CCc3ccccc32)CC1)c1ccc(Cl)cc1,,ClC(Cl)Cl,,O,,test
US20040122004A1,CC(=O)N(Cc1ccc([C@@H]2CCCC[C@H]2C(=O)OC(C)(C)C)cc1)c1ccccn1>>CC(=O)N(Cc1ccc([C@@H]2CCCC[C@H]2C(=O)O)cc1)c1ccccn1,,ClCCl,O=C(O)C(F)(F)F,[Na+].[OH-],,test
US20140066426A1,BrCc1ccccc1.CCOC(=O)c1[nH]c(C(F)(F)F)cc1-c1ccc(Cl)cc1F>>CCOC(=O)c1c(-c2ccc(Cl)cc2F)cc(C(F)(F)F)n1Cc1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150291655A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=C1NCCN1CCO>>Cc1ccc(S(=O)(=O)OCCN2CCNC2=O)cc1,,c1ccncc1,,CCOC(C)=O,,test
US20070270422A1,Nc1ccc(Oc2ccc(COc3ccc(C(F)(F)F)cc3)cn2)cc1.O=C(CCl)N1CCN(Cc2ccc3c(c2)OCO3)CC1>>O=C(CNc1ccc(Oc2ccc(COc3ccc(C(F)(F)F)cc3)cn2)cc1)N1CCN(Cc2ccc3c(c2)OCO3)CC1,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20160016910A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C(N)c1ccccc1F>>CCOC(=O)C(NC(=O)OC(C)(C)C)c1ccccc1F,,ClCCl,,Cl,,test
US20130331419A1,CCC(C(=O)OC)(c1ccc(Cl)cc1)n1ncc2c(N(COCC[Si](C)(C)C)S(C)(=O)=O)cccc21>>CCC(CO)(c1ccc(Cl)cc1)n1ncc2c(N(COCC[Si](C)(C)C)S(C)(=O)=O)cccc21,,C1CCOC1,,CO,[BH4-].[Li+],test
US20110003807A1,CCOC(=O)C(Cl)C(=O)c1ccccc1Cl.Cc1nn2ccccc2c1C(N)=S>>CCOC(=O)c1sc(-c2c(C)nn3ccccc23)nc1-c1ccccc1Cl,,CC(C)O,,Cl,,test
US20120172351A1,COC(=O)C[C@@H]1COc2cc(NCc3cccc(-n4c(C)nc5ccccc54)c3F)ccc21>>Cc1nc2ccccc2n1-c1cccc(CNc2ccc3c(c2)OC[C@H]3CC(=O)O)c1F,,C1CCOC1,CO,[Na+].[OH-],,test
US20120238564A1,CC(C)(C)OC(=O)NC1CCC(Nc2nccn3c(-c4cccc(NCc5ccccc5)n4)cnc23)CC1>>NC1CCC(Nc2nccn3c(-c4cccc(NCc5ccccc5)n4)cnc23)CC1,,CCO,Cl,,,test
US05985899,CCCCOC(=O)CCCCN.CI.O=C(O)C(F)(F)F>>CCCCNC.O=C(O)C(F)(F)F,,CN(C)C=O,ClCCl,[H-].[Na+],,test
US20140080808A1,Cn1cc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO[Si](C)(C)C(C)(C)C)C5)CC3)cc2)cn1>>Cn1cc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO)C5)CC3)cc2)cn1,,CO,,Cl,,test
US20100249192A1,NC(=O)c1cc(-c2ccc(Oc3cc(F)ccc3Br)cc2)no1>>N#Cc1cc(-c2ccc(Oc3cc(F)ccc3Br)cc2)no1,,ClCCl,,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US06274746B1,CC(C)(C)OO.CCOC(C)=O.C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43C)[C@@H]1CCC2=O>>CC(=O)O[C@H]1CC[C@@]2(C)C(=CC(=O)[C@H]3[C@@H]4CCC(=O)[C@@]4(C)CC[C@@H]32)C1,,CCOC(C)=O,,[Na+].[O-]Cl,,test
US04622395,CCc1ccc2c(c1)Oc1cc(CC)cc(C(N)=O)c1N2C(C)=O>>CCc1ccc2c(c1)Oc1cc(CC)cc(C(N)=O)c1N2,,CC(C)=O,CO,Cl,,test
US20080051418A1,BrP(CCC1OCCO1)(c1ccccc1)(c1ccccc1)c1ccccc1.CC(C)Oc1ccc(C=O)c(OCc2ccccc2)c1>>CC(C)Oc1ccc(C=CCC2OCCO2)c(OCc2ccccc2)c1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20140155398A1,CN(C)C=O.COC(=O)c1cc(F)cc(F)c1>>COC(=O)c1cc(F)c(C=O)c(F)c1,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20040116455A1,COc1ccccc1-c1ccc2c(c1)C(C(C)OCCc1cccc(Br)c1)=CC(C)(C)N2.COc1ccccc1-c1ccc2c(c1)C(C(C)OS(C)(=O)=O)=CC(C)(C)N2C(=O)OC(C)(C)C.OCCc1cccc(Br)c1>>COc1ccccc1-c1ccc2c(c1)C(C(C)OCCc1ccccc1Br)=CC(C)(C)N2,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20130331409A1,N#CBr.Nc1cccnc1Nc1ccc(OCc2ccccc2)cc1>>Nc1nc2cccnc2n1-c1ccc(OCc2ccccc2)cc1,,O,,C1CCOC1,O=C([O-])O.[Na+],test
US05344843,COC(=O)C(=O)c1ccc(OCc2ccc3ccccc3n2)cc1>>O=C(O)C(=O)c1ccc(OCc2ccc3ccccc3n2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20110184055A1,CC(C)(C)[Si](C)(C)OCCc1cccs1.CC(C)OC(=O)Cl>>CC(C)OC(=O)c1ccc(CCO)s1,,C1CCOC1,Cc1ccccc1,[Li]CCCC,,test
US04156732,NS(=O)(=O)c1cc(C(=O)Cl)ccc1Cl.c1ccc2sccc2c1>>NS(=O)(=O)c1cc(C(=O)c2csc3ccccc23)ccc1Cl,Cl[Ti](Cl)(Cl)Cl,Cc1ccccc1,,,,test
US20100152180A1,O=C1CCC(=O)N1Cl.O=c1[nH]c2ccccc2n2cccc12>>O=c1[nH]c2ccccc2n2c(Cl)ccc12,,ClC(Cl)(Cl)Cl,,,,test
US04835175,COc1cccc2cc(C(=O)O)[nH]c12.Cc1ccccc1>>CCCCOC(=O)c1cc2cccc(OC)c2[nH]1,,Cc1ccccc1,,O=S(Cl)Cl,,test
US20090099155A1,CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(SCCCN)c2CC1.O=C(O)C(F)(F)F.O=C(O)c1ccc(C(F)(F)F)cc1>>O=C(NCCCSc1c(Cl)ccc2c1CCNCC2)c1ccc(C(F)(F)F)cc1.O=C(O)C(F)(F)F,CN(C)c1ccncc1,CN(C)C=O,ClCCl,ClCCCl,On1nnc2ccccc21,test
US20130096084A1,CC(C)(C)OC(=O)N[C@@H]1CCCN(c2ccccc2)C1.Cl>>Cl.N[C@@H]1CCCN(c2ccccc2)C1,,CO,,,,test
US20130310380A1,CC1CNCC(C)O1.Cl.N=C(N)n1cncn1>>CC1CN(C(=N)N)CC(C)O1.Cl,,CCOCC,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20080300406A1,CC(C)(C)[Si](C)(C)O[C@H]1CC(=O)O[C@H](CO)C1>>CC(C)(C)[Si](C)(C)O[C@H]1CC(=O)O[C@H](C=O)C1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20040106606A1,CC(C)C1(CCc2ccsc2)CC(O)=CC(=O)O1.Cc1ccc(S(=O)(=O)Sc2cc(C)c(CO)cc2C(C)(C)C)cc1>>Cc1cc(SC2=C(O)CC(CCc3ccsc3)(C(C)C)OC2=O)c(C(C)(C)C)cc1CO,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070149608A1,BrCc1cccc(Br)c1.COC(=O)CCc1ccc(O)cc1>>COC(=O)CCc1ccc(OCc2cccc(Br)c2)cc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20030153570A1,C[Mg]Br.Cc1ccc(Cl)cc1-c1nc(Cl)nc(Nc2ccc(Br)cc2)n1>>Cc1nc(N)nc(-c2cc(Cl)ccc2C)n1,,C1CCOC1,,,,test
US06350757B1,CC[Si](CC)(CC)c1[nH]c2ccc(C(F)(F)F)cc2c1CCN>>NCCc1c[nH]c2ccc(C(F)(F)F)cc12,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05998433,CN(C)Cc1cc2c(o1)CCN(C(=O)C1CCN(C(=O)c3ccccc3)CC1)C2.Cl>>CN(C)Cc1cc2c(o1)CCN(C(=O)C1CCN(C(=O)c3ccccc3)CC1)C2.Cl,,CCOC(C)=O,CO,,,test
US20100130471A1,COC(=O)Cl.Cc1cccc(Oc2c(F)cccc2C(O)(CCCN)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1>>COC(=O)NCCCC(O)(c1cccc(F)c1Oc1cccc(C)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20130137680A1,CCOC(=O)c1ccc2cc(C(=O)OCC)n(CC(C)(C)CNC(=O)OC(C)(C)C)c2n1>>CCOC(=O)c1ccc2cc(C(=O)OCC)n(CC(C)(C)CN)c2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110053904A1,CC(C)(C)OC(=O)NC1CCCC1N.O=C1CCCC1>>CC(C)(C)OC(=O)NC1CCCC1NC1CCCC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20090264416A1,CC(C)(C)NC(=O)c1cccc(CCl)c1.CC(C)[C@H]1CN(C(=O)c2ccc(N)c(F)c2)CCN1>>CC(C)[C@H]1CN(C(=O)c2ccc(N)c(F)c2)CCN1Cc1cccc(C(=O)NC(C)(C)C)c1,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US06329381B1,BrBr.CC(C)(C)CNc1nc(N)c2ncn(Cc3ccccc3)c2n1>>CC(C)(C)CNc1nc(N)c2nc(Br)n(Cc3ccccc3)c2n1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20150225388A1,CC(=O)c1ccc(S(=O)(=O)Cl)cc1.NCCC(F)(F)F>>CC(=O)c1ccc(S(=O)(=O)NCCC(F)(F)F)cc1,,CN(C)C=O,,CN1CCOCC1,Cl,test
US20160122342A1,C=CC1CO1.COc1nc(C)cc(C)c1C#N>>C=CC(O)CCc1cc(C)nc(OC)c1C#N,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20060009509A1,O=C(O)Cc1cccc(F)c1[N+](=O)[O-]>>O=C1Cc2cccc(F)c2N1,[Pd],CC(=O)O,,,,test
US20100105657A1,CN1CCOc2ccc([N+](=O)[O-])cc2C1>>CN1CCOc2ccc(N)cc2C1,[Pd],CCO,,[H][H],,test
US20040014802A1,CCCC(=O)Nc1nn(COCC[Si](C)(C)C)c2cc(-c3ccc(F)cc3)ccc12>>CCCC(=O)Nc1n[nH]c2cc(-c3ccc(F)cc3)ccc12,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20050148624A1,CB(O)O.COC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc2c(c1)OCO2>>COC(=O)c1c(-c2ccccc2)c2cc(C)ccc2c(=O)n1Cc1ccc2c(c1)OCO2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,O,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20140309192A1,Cc1ccc(C(=O)O)c(F)c1F.O=C1CCC(=O)N1Br>>O=C(O)c1ccc(CBr)c(F)c1F,CC(C)(C#N)N=NC(C)(C)C#N,ClC(Cl)(Cl)Cl,,,,test
US20160016908A1,COc1cccc(N[C@H]2c3ccccc3N(C(C)=O)[C@@H](C3CC3)[C@@H]2C)n1>>CC(=O)N1c2ccccc2[C@H](Nc2cccc(O)n2)[C@@H](C)[C@@H]1C1CC1,,CC#N,,[I-].[Na+],,test
US20120010207A1,COc1ccc(Cl)cc1C(C)O>>CCc1cc(Cl)ccc1OC,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US05028603,Cc1nnc2n1-c1sc(C(C)O)cc1C(c1ccccc1Cl)=NC2.O=C(Cl)c1ccccc1>>Cc1nnc2n1-c1sc(C(C)OC(=O)c3ccccc3)cc1C(c1ccccc1Cl)=NC2.Cl,,c1ccncc1,,,,test
US20130327251A1,CCCCCCCCCCCCCCCCCCOc1cc(CCSC#N)cc(OCCCCCCCCCCCCCCCCCC)c1>>CCCCCCCCCCCCCCCCCCOC1(OCCCCCCCCCCCCCCCCCC)C=CC=C(CCS)C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20160272585A1,COC(=O)c1ccc([C@H](C)NC(=O)[C@@]2(C)CCCCN2CCOc2ccccc2)cc1.Cl>>C[C@H](NC(=O)[C@@]1(C)CCCCN1CCOc1ccccc1)c1ccc(C(=O)O)cc1.Cl,,C1CCOC1,CO,C1COCCO1,[Na+].[OH-],test
US20140073620A1,CC(C)(C#N)c1ccccc1Br.CC(C)(C)O>>CC(C)(C(N)=O)c1ccccc1Br,,ClCCl,,[Na+].[OH-],,test
US20100152168A1,CC(C)(C)OC(=O)Nc1ccc(C#N)cc1N.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)n1c(=O)[nH]c2cc(C#N)ccc21,,ClCCl,,CCN(CC)CC,,test
US20090176786A1,CNc1ccc(SC(F)(F)F)cc1F.O=C=NC(=O)c1c(F)cccc1F>>CN(C(=O)NC(=O)c1c(F)cccc1F)c1ccc(SC(F)(F)F)cc1F,,CCOCC,,CCCCCC,,test
US05338719,CC(=O)C1(C)Oc2cc(Oc3c(F)cc(C(F)(F)F)cc3Cl)ccc2N(C)C1=O.NO>>CC(=NO)C1(C)Oc2cc(Oc3c(F)cc(C(F)(F)F)cc3Cl)ccc2N(C)C1=O,,CCO,,Cl,[Na+].[OH-],test
US20120004225A1,CN(C)CCCN.NS(=O)(=O)c1cc(C(=O)O)c(NCc2ccco2)cc1Cl>>CN(C)CCCc1c(Cl)c(S(N)(=O)=O)cc(C(N)=O)c1NCc1ccco1,,C1CCOC1,O,O=C(n1ccnc1)n1ccnc1,,test
US20140243283A1,Brc1ccc2c(c1)Cc1cc(Br)ccc1-2.O=S(=O)([O-])CCCC1(CCCS(=O)(=O)[O-])OCCO1>>Brc1ccc2c(c1)C1(CCC3(CC1)OCCO3)c1cc(Br)ccc1-2,,C1CCOC1,,[H-].[Na+],,test
US20160031899A1,CC(C)(C)C(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CCC(=O)[C@@]4(C)CC[C@@H]32)C1.NO>>CC(C)(C)C(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CCC(=NO)[C@@]4(C)CC[C@@H]32)C1,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20150376181A1,COC(=O)c1[nH]c(=O)cnc1C.O=C1CCC(=O)N1Br>>COC(=O)c1[nH]c(=O)c(Br)nc1C,,ClCCl,,,,test
US20060025350A1,CCN(CC)S(F)(F)F.O=C(O[C@H]1[C@H](O)CN(C(=O)OCc2ccccc2)[C@@H]1CO)c1ccccc1>>O=C(O[C@H]1[C@H](O)CN(C(=O)OCc2ccccc2)[C@H]1CF)c1ccccc1,,COCCOC,,O=C([O-])O.[Na+],,test
US20140155407A1,CC(O)c1ccc(-c2ccoc2)nc1.O=C(n1ccnc1)n1ccnc1>>CC(OC(=O)n1ccnc1)c1ccc(-c2ccoc2)nc1,,CC#N,,,,test
US08598187B2,Br.Cn1c(CCNC(=O)OCc2ccccc2)nc(-c2ccncn2)cc1=O>>Br.Cn1c(CCN)nc(-c2ccncn2)cc1=O,,CC(=O)O,,,,test
US20100087543A1,CS(=O)COc1ccc(Cl)cc1Cl.ClCCl>>ClCOc1ccc(Cl)cc1Cl,,ClCCl,,CC(=O)Cl,,test
US20140057902A1,COC(CC(OC)OC)OC.NNc1cccc2cnccc12>>c1cc(-n2cccn2)c2ccncc2c1,,CCO,ClCCl,,,test
US20150336979A1,CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2[C@@H](NC(=O)NC3CCCCC3)CO[C@H]12>>O=C(NC1CCCCC1)N[C@H]1CO[C@@H]2[C@H](O)CO[C@H]12,,Cl,,C1COCCO1,,test
US05166357,COC(=O)c1ncc(C23CCCN(CC2)C3)o1>>OCc1ncc(C23CCCN(CC2)C3)o1,,Cc1ccccc1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20070213331A1,CCCN(C)C(=O)c1cc(C(=O)OCc2ccccc2)cc(-c2ccncc2)c1>>CCCN(C)C(=O)c1cc(C(=O)O)cc(-c2ccncc2)c1,[Pd],CO,,,,test
US20100035863A1,CNC1CCN(c2cc(C3CCCC3)nc(NCc3ccc(OC)cc3)n2)C1>>CNC1CCN(c2cc(C3CCCC3)nc(N)n2)C1,,O=C(O)C(F)(F)F,,,,test
US20040092582A1,COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(-c3ccc(N)cc3)c1)=NC(C)(C)C2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(-c3ccc(NC(=O)C(F)(F)F)cc3)c1)=NC(C)(C)C2,,C1CCOC1,,CCN(CC)CC,O,test
US20040063946A1,Cc1cccc(-c2nc(N)sc2-c2ccnc(NC3CCCC3)c2)c1.O=C(Cl)c1ccc(Cl)nc1>>Cc1cccc(-c2nc(NC(=O)c3ccc(Cl)nc3)sc2-c2ccnc(NC3CCCC3)c2)c1,CN(C)c1ccncc1,CC(=O)N(C)C,,Cl,O=C([O-])O.[Na+],test
US04826987,CCCCBr.COc1ccc(N)c(Cl)c1Cl>>CCCCNc1ccc(OC)c(Cl)c1Cl,,COCCO,,O=C([O-])O.[Na+],,test
US20150065499A1,COC(=O)CS.N#Cc1cnc2ccc(F)cc2c1Cl>>COC(=O)c1sc2c(cnc3ccc(F)cc32)c1N,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160222022A1,COC(=O)c1ccc2c(c1)OC[C@H](c1ccc(C(F)(F)F)cc1)N(C(=O)C1CCOCC1)C2.NO>>O=C(NO)c1ccc2c(c1)OC[C@H](c1ccc(C(F)(F)F)cc1)N(C(=O)C1CCOCC1)C2,,C1CCOC1,CO,[Na+].[OH-],,test
US20100298324A1,COc1ccc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)nc1OC.NCc1cccc(Cl)c1>>COc1ccc(-n2c(=S)[nH]c3cc(C(=O)NCc4cccc(Cl)c4)ccc3c2=O)nc1OC,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04717783,C[Si](C)(C)C1=CC=CC1.C[Si](C)(C)Cl>>C[Si](C)(C)C1=CCC([Si](C)(C)C)=C1,,,,[Li]CCCC,,test
US20120095007A2,C1CCOC1.CCN(CC)CC.NC(=O)OC(CCN1CCN(c2ccc(O)cc2)CC1)c1ccccc1>>NC(=O)OC(CCN1CCN(c2ccc(OC3CCCC3)cc2)CC1)c1ccccc1,,O,,,,test
US04370340,CCOC(=O)CBr.O=c1[nH]c2c(Oc3ccccc3)cccc2s1>>CCOC(=O)Cn1c(=O)sc2cccc(Oc3ccccc3)c21,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050187387A1,C[Mg]Br.O=Cc1ccc2ncccc2c1>>CC(O)c1ccc2ncccc2c1,,C1CCOC1,,[Cl-].[NH4+],,test
US04780471,C=C(C)c1ccccc1OCc1ccc(Cl)cc1Cl.O=C1CCC(=O)N1Br>>C=C(CBr)c1ccccc1OCc1ccc(Cl)cc1Cl,CC(C)(C#N)N=NC(C)(C)C#N,ClC(Cl)(Cl)Cl,,O,,test
US20060287522A1,CSc1ccccc1-c1ccc(C(=O)O)cc1.Cc1cccc(C)c1-c1ccc(C(=O)N2Cc3ccc(C(=O)NCc4cccnc4)n3Cc3ccccc32)cc1>>CSc1ccccc1-c1ccc(C(=O)N2Cc3ccc(C(=O)NCc4cccnc4)n3Cc3ccccc32)cc1,,c1ccncc1,,O=S(Cl)Cl,,test
US20030055085A1,C#Cc1cccc(O)c1.ON=C(Cl)c1ccccn1>>Oc1cccc(-c2cc(-c3ccccn3)no2)c1,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US20110269744A1,CC(C)I.CC1CNc2cc3c(cc2O1)CCN(C(=O)OC(C)(C)C)CC3>>CC1CN(C(C)C)c2cc3c(cc2O1)CCN(C(=O)OC(C)(C)C)CC3,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20090186886A1,CC(=O)Nc1ccc2c(c1)CC(C)C2.O=[N+]([O-])O>>CC(=O)Nc1cc2c(cc1[N+](=O)[O-])CC(C)C2,,O=C(O)C(F)(F)F,,,,test
US20100292143A1,CC(C)C(=O)Cl.COC(=O)c1ccc[nH]1>>COC(=O)c1cc(C(=O)C(C)C)c[nH]1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20150141400A1,CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Br)c(CN3CCC[C@H](NC)C3)c(C(F)(F)F)cc2c1=O.N#C[Cu]>>CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(C#N)c(CN3CCC[C@H](NC)C3)c(C(F)(F)F)cc2c1=O,,CN(C)C=O,,,,test
US20110269734A1,CS(=O)(=O)Cl.C[C@H](CCO)C1CCN(C(=O)OC(C)(C)C)CC1>>C[C@H](CCOS(C)(=O)=O)C1CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,CCN(CC)CC,,test
US20070232583A1,CC(C)(C)NS(=O)(=O)c1ccc(-c2cn(-c3nc(-c4ccc(Cl)c(Cl)c4)cc(C(F)(F)F)n3)cn2)cc1>>NS(=O)(=O)c1ccc(-c2cn(-c3nc(-c4ccc(Cl)c(Cl)c4)cc(C(F)(F)F)n3)cn2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140128386A1,CCOC(=O)c1c(C)nc2c(O)cc(C)cn12.Fc1cccnc1CCl>>CCOC(=O)c1c(C)nc2c(OCc3ncccc3F)cc(C)cn12,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US04086219,CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O.Cl>>CC(C)C[C@H](N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O.Cl,[Pd],CO,,,,test
US20050107399A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc2c(O)cccc2c1>>CC(C)(C)OC(=O)c1ccc2c(O)c(N)ccc2c1,,CCOC(C)=O,,O=C([O-])O.[Na+],,test
US20150299121A1,O=C(OCc1ccccc1)C1CCC(F)C1>>O=C(O)C1CCC(F)C1,[Pd],CO,,,,test
US05534573,CC(Cl)(Cl)Cl.CCOP(=O)(OCC)c1nc(NC(C)C)nc(NC(C)C)n1>>CC(C)Nc1nc(Cl)nc(NC(C)C)n1,,C1COCCO1,,Cc1ccccc1,,test
US09248117B2,CC(C)(CCS)NC(=O)OCc1ccccc1.OCCOCCCl>>CC(C)(CCSCCOCCO)NC(=O)OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070173506A1,BrBr.CC(=O)Nc1nc(CN(C)C)cs1>>CC(=O)Nc1nc(CN(C)C)c(Br)s1,,CC(=O)O,,,,test
US20070066657A1,CCOC(=O)C(F)(F)C(=O)C(F)(F)C(=O)OCC.SCCCS>>CCOC(=O)C(F)(F)C1(C(F)(F)C(=O)OCC)SCCCS1,,ClCCl,,O,,test
US20140179667A1,BrBr.COC(=O)c1cccc(O)c1C>>COC(=O)c1c(Br)ccc(O)c1C,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US04247548,Cc1cc(O)no1.O=C(Cl)c1ccccc1>>Cc1cc(OC(=O)c2ccccc2)no1,,CCN(CC)CC,,,,test
US20100288634A1,[O-][n+]1ccc(Br)cc1-c1ccccn1>>Brc1ccnc(-c2ccccn2)c1,,ClC(Cl)Cl,,ClP(Cl)Cl,,test
US20070072925A1,CCB(CC)CC.Cc1ccc(S(=O)(=O)N/N=C/c2cccc(C#Cc3ccc(OC(F)F)cc3)c2)cc1>>CCCc1cccc(C#Cc2ccc(OC(F)F)cc2)c1,,C1CCOC1,,O,[Na+].[OH-],test
US20020165241A1,Cc1cccnc1N.O=C(O)C1CCN(C(=O)OCc2ccccc2)CC1>>Cc1cccnc1NC(=O)C1CCN(C(=O)OCc2ccccc2)CC1,,CN(C)C=O,,ClCCCl,On1nnc2cccnc21,test
US20150011546A1,CCOC(=O)c1c(C)n(C(C)c2ccccc2)c2ccccc12>>Cc1c(C(=O)O)c2ccccc2n1C(C)c1ccccc1,,O,,CO,[K+].[OH-],test
US20070032515A1,CCOC(=O)C(F)(F)F.COc1ccc(CC#N)cc1OC>>COc1ccc(C(C#N)C(=O)C(F)(F)F)cc1OC,,CCO,,C,C[O-].[Na+],test
US20060052392A1,CCOC(=O)CC1c2cc(C)c(C)cc2C(=O)N1c1cccnc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)CC1c2cc(C)c(C)cc2C(=S)N1c1cccnc1,,Cc1ccccc1,,,,test
US04273932,CCI.CCOC(=O)c1cnc2c(c1O)C(=NO)CCC2>>CCON=C1CCCc2ncc(C(=O)OCC)c(O)c21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050059651A1,CCCCON=O.COc1cc(NC(=O)c2cc(Oc3ccccc3)ccc2N)ccc1OCCN1CCCC1>>COc1cc(-n2nnc3ccc(Oc4ccccc4)cc3c2=O)ccc1OCCN1CCCC1,O=C(O)C(F)(F)F,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20070149608A1,COC(=O)CCc1ccc(OCc2cccc(-c3ccc(O)cc3C)c2)cc1.OCCCc1ccccn1>>COC(=O)CCc1ccc(OCc2cccc(-c3ccc(OCCCc4ccccn4)cc3C)c2)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150087639A1,CC(C)(Cc1ccc2ccccc2c1)Nc1ccc([N+](=O)[O-])cc1Cl>>CC(C)(Cc1ccc2ccccc2c1)Nc1ccc(N)cc1Cl,[Fe],C1CCOC1,,Cl,O,test
US05723452,COc1cc(C)cc(S(=O)(=O)c2cccc(F)c2C#N)c1.N>>COc1cc(C)cc(S(=O)(=O)c2cccc(N)c2C#N)c1,,C1CCOC1,CCO,,,test
US20110112180A1,C=CCC1=C(O)C(=O)c2ccccc2C1=O>>O=C1C=Cc2ccccc2C1=O,,CCO,,O=S(=O)(O)O,,test
US20110306607A1,CCOC(OCC)C1C(=O)c2ccccc2OC12CCN(C(=O)OC(C)(C)C)CC2.Cl>>CCO/C=C1\C(=O)c2ccccc2OC12CCNCC2.Cl,,Cc1ccccc1,,,,test
US07067674B1,CCC1(CC)c2cc(Br)ccc2-c2ccc(C=O)cc21.Nc1ccccc1S>>CCC1(CC)c2cc(Br)ccc2-c2ccc(-c3nc4ccccc4s3)cc21,,O,,CS(C)=O,,test
US20030199455A1,O=N[O-].O=[N+]([O-])c1ccc2cc[nH]c2c1>>c1ccc2[nH]ncc2c1,,O,,Cl,,test
US20030050309A1,O=C(O)C1(c2ccc(Cl)cc2)CCC1.OC1(COc2ccc(C(F)(F)F)cc2)CCCNC1>>O=C(N1CCCC(O)(COc2ccc(C(F)(F)F)cc2)C1)C1(c2ccc(Cl)cc2)CCC1,,ClCCl,O,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US04623647,CCOc1cc2c(cc1OCC)C1C(CO)COCN1CC2.O=S(Cl)Cl>>CCOc1cc2c(cc1OCC)C1C(CCl)COCN1CC2.Cl,,c1ccccc1,,,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OC(C)C3(O)CCC3)CC2)c2ncnn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n([C@@H]2CC[C@@H](OC(C)C3(O)CCC3)CC2)c2ncnn12,,CCOC(C)=O,CS(C)=O,[Cl-].[Na+],,test
US06008387,C=Cc1ccccc1.OO>>c1ccc(C2CO2)cc1,,ClCCl,O,O=C([O-])O.[Na+],,test
US20150307497A1,COC(=O)c1c(Cl)ncnc1Cl.OC1CCC1>>COC(=O)c1c(Cl)ncnc1OC1CCC1,,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US20100297113A1,CCOC(=O)/C(C)=C/c1c(C)c(OC)c2ccccc2c1OC.COc1cc(/C=C(\C)C(=O)O)c(OC)c2ccccc12>>COc1c(C)c(/C=C(\C)C(=O)O)c(OC)c2ccccc12,,CC(C)=O,,,,test
US20090054431A1,Nc1ccc(Oc2ccc(C=O)cc2)cc1[N+](=O)[O-].O=CO>>O=CNc1ccc(Oc2ccc(C=O)cc2)cc1[N+](=O)[O-],,C1CCOC1,,,,test
US05430042,COC(=O)c1cc2nc(S)[nH]c2cc1C.COc1ccnc(CCl)c1OC>>COC(=O)c1cc2nc(SCc3nccc(OC)c3OC)[nH]c2cc1C,,CO,O,Cl,[Na+].[OH-],test
US20110118235A1,CC(C)(C)[Si](C)(C)Cl.CCCNCC(C)O>>CCCNCC(C)O[Si](C)(C)C(C)(C)C,CN(C)c1ccncc1,ClCCl,,O,,test
US20080004327A1,C#CCO[Si](C)(C)C(C)(C)C.FC(F)(Br)Br>>CC(C)(C)[Si](C)(C)OCC#CC(F)(F)Br,,C1CCOC1,,[Li]CCCC,,test
US04762844,Cc1ccc(C(=O)O)cc1F.O=[N+]([O-])O>>Cc1cc([N+](=O)[O-])c(C(=O)O)cc1F,,O=S(=O)(O)O,,,,test
US20060199806A1,COC(=O)c1ccc(Br)c(O)c1.COS(=O)(=O)OC>>COC(=O)c1ccc(Br)c(OC)c1,,CC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110207935A1,COC(=O)c1ccc(B(O)O)cc1.N#Cc1cc(Cl)nc2ccccc12.c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>COC(=O)c1ccc(-c2cc(C#N)c3ccccc3c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20020013466A1,COC(=O)CBr.Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3cccc(O)c3)c(C#N)cc2F)c1=O>>COC(=O)COc1cccc(Oc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2C#N)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090069370A1,CC(C)(C)OC(=O)N1CCC(N)CC1.COC(=O)c1ccc(Br)cc1CBr>>CC(C)(C)OC(=O)N1CCC(N2Cc3cc(Br)ccc3C2=O)CC1,,CO,ClCCl,CC(C)NC(C)C,,test
US20160257951A1,C1=COCC1.CCCCCCCCCCC(CCCCCCC/C=C\C[C@H](O)CCCCCC)OC(=O)OCCCN(C)C>>CCCCCCCCCCC(CCCCCCC/C=C\C[C@@H](CCCCCC)OC1CCCO1)OC(=O)OCCCN(C)C,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20130109653A1,COc1ccc(COC2CC(C)(C)Cc3nc(C4CCN(c5ncc(C(O)CC(C)C)cn5)CC4)c(C(F)c4ccc(C(F)(F)F)cc4)c(C4CCC(F)(F)CC4)c32)cc1>>CC(C)/C=C/c1cnc(N2CCC(c3nc4c(c(C5CCC(F)(F)CC5)c3C(F)c3ccc(C(F)(F)F)cc3)C(O)CC(C)(C)C4)CC2)nc1,,C1COCCO1,,Cl,O=C([O-])O.[Na+],test
US06180636B2,NC(=O)c1cc2c(Nc3cccc(Cl)c3)ncnc2[nH]1>>N#Cc1cc2c(Nc3cccc(Cl)c3)ncnc2[nH]1,,CC(=O)N(C)C,,O=P(Cl)(Cl)Cl,O=C([O-])O.[Na+],test
US04670447,CC(=O)N1CCC(C(=O)c2ccc(F)cc2F)CC1.NN>>CC(=O)N1CCC(C(=NN)c2ccc(F)cc2F)CC1,,CCO,,O,,test
US05204336,Cc1ccc2ccccc2c1O.ClCC(CCl)OC(CCl)CCl>>Cc1cc(C=O)c2ccccc2c1O,,ClCCl,,,,test
US20130029962A1,NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1.O=C(Nc1ccc(N2CCC2)nc1)Oc1ccccc1>>O=C(NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)Nc1ccc(N2CCC2)nc1,,CS(C)=O,O,CCN(CC)CC,,test
US20070249642A1,O=C(Cl)c1ccccc1.O=c1[nH]cc(I)c(=O)[nH]1>>O=C(c1ccccc1)n1c(=O)[nH]cc(I)c1=O,,c1ccncc1,,O,,test
US04002623,CN1CCN(CCCNc2ccc(Cl)cc2N)CC1.N#CBr>>CN1CCN(CCCn2c(N)nc3cc(Cl)ccc32)CC1,,CCO,,O,[Na+].[OH-],test
US20100249119A1,Cc1ccc(Oc2ccc3nc(N)sc3n2)cc1NC(=O)c1cccc(C(C)(C)C#N)c1.O=C(Cl)CCl>>Cc1ccc(Oc2ccc3nc(NC(=O)CCl)sc3n2)cc1NC(=O)c1cccc(C(C)(C)C#N)c1,,CCOC(C)=O,CN(C)C=O,,,test
US20150361100A1,CC(c1cc2ccccn2c1C1=CCN(C(=O)OC(C)(C)C)CC1)n1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc21>>CC(c1cc2ccccn2c1C1=CCNCC1)n1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100016279A1,Brc1ccc(OCc2ccccc2)cc1.O=C1CCN(C(=O)OCc2ccccc2)CC1>>O=C(OCc1ccccc1)N1CCC(O)(c2ccc(OCc3ccccc3)cc2)CC1,,C1CCOC1,,[Li]CCCC,,test
US20120015980A1,CNS(=O)(=O)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1.COC(=O)c1cc(CS(C)(=O)=O)nn1-c1ncccc1Cl>>COC(=O)c1cc(CN(C)S(=O)(=O)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)nn1-c1ncccc1Cl,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20130158009A1,N#Cc1ccc(Cl)nn1.N[C@H]1CCN(C2CCN(c3ncc(C(F)(F)F)cc3Cl)CC2)C1=O>>N#Cc1ccc(N[C@H]2CCN(C3CCN(c4ncc(C(F)(F)F)cc4Cl)CC3)C2=O)nn1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20130143878A1,CN=Cc1ccccc1NC(=O)OC.COc1cc2c(cc1OC)C(=O)OC(=O)C2>>COC(=O)Nc1ccccc1[C@H]1[C@@H](C(=O)O)c2cc(OC)c(OC)cc2C(=O)N1C,,ClC(Cl)Cl,,,,test
US03995052,CCOC(=O)C(C)=O.OCCC1=Cc2ccccc2C1>>CC1(C(=O)O)OCCC2=CC3=CC=CCC3=C21,,c1ccccc1,,CCOCC,FB(F)F,test
US04837238,CCOC=C(C(C)=O)C(=O)OCC.O=[N+]([O-])c1cn[nH]c1>>CCOC(=O)C(=CNc1cn[nH]c1)C(C)=O,[Pd],CCO,,,,test
US20090186870A1,COC(=O)c1cc(-c2ncccc2[N+](=O)[O-])ccc1Cl>>COC(=O)c1cc(-c2ncccc2N)ccc1Cl,[Pd],CCOC(C)=O,,,,test
US20120122900A1,CC(=O)Cc1ccccc1C.COC(=O)[C@@H](CI)NC(=O)OC(C)(C)C>>COC(=O)[C@H](CC(C(C)=O)c1ccccc1C)NC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140057299A1,NCC1CC(=O)Nc2cc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)ccc21.O=C1CCC(=O)O1>>O=C(O)CCC(=O)NCC1CC(=O)Nc2cc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)ccc21,,C1CCOC1,,,,test
US20040110945A1,COC(=O)Cc1ccc(Nc2nc3c(Cl)cccc3s2)c(Cl)c1>>O=C(O)Cc1ccc(Nc2nc3c(Cl)cccc3s2)c(Cl)c1,,C1CCOC1,,[Na+].[OH-],,test
US05739132,O=C(Cl)Cc1ccccc1.O=C1c2ccccc2C(=O)N1C1Cc2ccccc2C1>>O=C(Cc1ccccc1)c1ccc2c(c1)CC(N1C(=O)c3ccccc3C1=O)C2,,CC(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20070043063A1,Brc1cccc(Br)n1.NCc1ccc(Cl)cc1>>Clc1ccc(CNc2cccc(Br)n2)cc1,,CCOCC,,,,test
US20130072495A1,CC(C)(C)OC(=O)N1CCC(n2cc(B3OC(C)(C)C(C)(C)O3)cn2)CC1.COc1ccc(F)c(Cl)c1[C@@H](C)c1n[nH]c2ncc(Br)cc12>>COc1ccc(F)c(Cl)c1[C@@H](C)c1n[nH]c2ncc(-c3cnn(C4CCNCC4)c3)cc12,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20100179128A1,CCCCCn1c(=O)n(CCCCC(=O)O)c(=O)c2[nH]c(Cl)nc21.Cc1cccc(CN)c1>>CCCCCn1c(=O)n(CCCCC(=O)NCc2cccc(C)c2)c(=O)c2[nH]c(Cl)nc21,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20160244437A1,Cc1ccc(S(=O)(=O)N2CCOCC2)cc1-c1cccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc3c(=O)[nH][nH]c3c2)c1.Cl>>Cc1ccc(S(=O)(=O)N2CCOCC2)cc1-c1cccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc3c(=O)[nH][nH]c3c2)c1.Cl,,C1COCCO1,,,,test
US20090186874A1,CCOC(=O)C1=C(c2ccccc2)CN(Cc2ccccc2)CC1.Cl>>Cl.O=C(O)C1=C(c2ccccc2)CN(Cc2ccccc2)CC1,,CC(=O)O,,,,test
US05925792,CCC(=O)CC(=O)OC.O=S(=O)(Cl)Cl>>CCC(=O)C(Cl)C(=O)OC,,Cc1ccccc1,,,,test
US20040152742A1,CCNCC.O=[N+]([O-])c1ccc(CCl)c(Cl)c1>>CCN(CC)Cc1ccc([N+](=O)[O-])cc1Cl,,C1CCOC1,,,,test
US20120164097A1,O=C(CCl)c1ccccc1.c1cscn1>>O=C(Cc1[nH+]ccs1)c1ccccc1.[Cl-],,CCOC(C)=O,,,,test
US04617314,CCN1CCCC1CN.CCOC(=O)Cl.CSc1cc2c(c(C(=O)O)c1)OC(C)C2>>CCN1CCCC1CNC(=O)c1cc(SC)cc2c1OC(C)C2.Cl,,CC(C)=O,,CCN(CC)CC,,test
US20040157804A1,CCOC(=O)C(C)OP(=O)(CCNC(=O)c1c2c(c(O)c3ncccc13)C(=O)N(Cc1ccc(F)cc1)C2)Oc1ccccc1>>CC(OP(=O)(O)CCNC(=O)c1c2c(c(O)c3ncccc13)C(=O)N(Cc1ccc(F)cc1)C2)C(=O)O,,CC#N,,O,[Na+].[OH-],test
US20110015175A1,CI.COc1cc(NC(N)=S)ccc1-n1cnc(C)n1>>COc1cc(NC(=N)SC)ccc1-n1cnc(C)n1.I,,CCO,,,,test
US20080161289A1,CN(C)c1ccc(B(O)O)cc1.O=C(N1CCc2nc(I)sc2CC1)C(F)(F)F>>CN(C)c1ccc(-c2nc3c(s2)CCNCC3)cc1,,C1COCCO1,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20030229094A1,Cc1ccccc1NC(=O)CCl.c1ccc(N2CCNCC2)nc1>>Cc1ccccc1NC(=O)CN1CCN(c2ccccn2)CC1,,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20130237525A1,COc1cccc(OC)c1C(CO)NCc1ccc(OC(F)(F)F)cc1.O=C(Cl)CCl>>COc1cccc(OC)c1C(CO)N(Cc1ccc(OC(F)(F)F)cc1)C(=O)CCl,,ClCCl,O,[Na+].[OH-],,test
US20040132727A1,COc1cc2nccc(Oc3ccc(NC(=O)COc4ccc(C)cc4)cc3)c2cc1OC>>COc1cc2nccc(Oc3ccc(NCCOc4ccc(C)cc4)cc3)c2cc1OC,,C1CCOC1,,Cl,[Na+].[OH-],test
US20140065103A1,CC(C)(C)OC(=O)NCCCCCC(=O)O.COC(=O)c1sc(C#CC(C)C)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C1CCNCC1>>COC(=O)c1sc(C#CC(C)C)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C1CCN(C(=O)CCCCCNC(=O)OC(C)(C)C)CC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US03993658,N=C1CSC(=N)N1.N=C1NC(=N)C2=C1CCCC2>>N=C1NC(=N)C(=C2NC(=N)C3=C2CCCC3)S1,,CO,,Cl,,test
US20110046133A1,Cc1ccc(NS(=O)(=O)c2ccc(N)c(N)c2)cc1C.O=Cc1c(Cl)cccc1Cl>>Cc1ccc(NS(=O)(=O)c2ccc3nc(-c4c(Cl)cccc4Cl)[nH]c3c2)cc1C,,CS(C)=O,,CO,,test
US20120149707A1,CO/C=C(/C(=O)OC)c1ccccc1CBr.COCC(=O)c1cc(C)c(O)cc1C>>CO/C=C(/C(=O)OC)c1ccccc1COc1cc(C)c(C(=O)COC)cc1C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070197558A1,BrP(Br)Br.OCc1cc(F)ccc1F>>Fc1ccc(F)c(CBr)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20110015238A1,CCCCOC(=O)/C=C/c1csc(CN2C(=O)CC[C@@H]2CO[Si](C)(C)C(C)(C)C)n1>>CCCCOC(=O)/C=C/c1csc(CN2C(=O)CC[C@@H]2CO)n1,,CCCCO,,Cl,,test
US20060264429A1,C[Mg]Br.Cc1ccc2c(N3CCN(CCC(=O)c4ccc5c(c4)NC(=O)CO5)CC3)cccc2n1>>Cc1ccc2c(N3CCN(CCC(C)(O)c4ccc5c(c4)NC(=O)CO5)CC3)cccc2n1,,C1CCOC1,,CCOCC,,test
US20060281772A1,COc1cc2ncnc(C3CCN(C(=O)Nc4ccc(I)cc4)CC3)c2cc1OC.OB(O)c1cncnc1>>COc1cc2ncnc(C3CCN(C(=O)Nc4ccc(-c5cncnc5)cc4)CC3)c2cc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],,test
US20030186985A1,CCOC(=O)C(=O)c1cccnc1.NO>>CCOC(=O)/C(=N/O)c1cccnc1,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20130280245A1,CO.COc1ccc(-c2ccc3nnc(-c4cccnc4Cl)n3c2)cc1>>COc1ccc(-c2ccc3nnc(-c4cccnc4OC)n3c2)cc1,,CO,,C[O-].[Na+],,test
US06184180B2,CCCCCCCCCCCCCCCCCCSC.CI>>CCCCCCCCCCCCCCCCCC[S+](C)C.[I-],,CC(C)=O,,,,test
US20120208791A1,Clc1ncc(Cl)c(Cl)n1.N>>Nc1nc(Cl)ncc1Cl,,CO,,,,test
US20040097739A1,CCOC(=O)C(C)(C)Oc1ccc(C(O)CCc2nc(-c3ccccc3Cl)oc2C(C)C)cc1>>CC(C)c1oc(-c2ccccc2Cl)nc1CCC(O)c1ccc(OC(C)(C)C(=O)O)cc1,,CCO,O,Cl,[Li+].[OH-],test
US06184236B2,CC(=O)OC(C)=O.c1ccc(CCCN[C@@H]2CC[C@@H](c3ccc(OCc4ccccc4)cc3)CC2)cc1>>CC(=O)N(CCCc1ccccc1)[C@@H]1CC[C@@H](c2ccc(OCc3ccccc3)cc2)CC1,,c1ccncc1,,,,test
US20150218102A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc3cc(Oc4ccc(C(F)F)cn4)ccc3n2)CC1>>O=C(c1ccc2cc(Oc3ccc(C(F)F)cn3)ccc2n1)N1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030096705A1,CCOC(=O)C1CCNCC1.Cc1nn(C)c2ncc(C(=O)NC(=O)Nc3cccc(OC(C)C)c3)c(Cl)c12>>CCOC(=O)C1CCN(c2c(C(=O)NC(=O)Nc3cccc(OC(C)C)c3)cnc3c2c(C)nn3C)CC1,,C1CCOC1,,,,test
US20100016279A1,CN(C)C=O.Fc1ccc(C(F)F)c(Br)c1>>O=Cc1cc(F)ccc1C(F)F,,C1CCOC1,,Cl,,test
US04680287,CCCCCCCC/C=C\CCCCCCCC(=O)Cl.CCCCCCCCCCCCCCCCCCNC1O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]1O>>CCCCCCCC/C=C\CCCCCCCC(=O)N(CCCCCCCCCCCCCCCCCC)C1O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]1O,,CO,ClCCl,,,test
US20090036446A1,COCc1cc2cc(OC)ccc2n1-c1ccc(OCc2ccccc2)cc1>>COCc1cc2cc(OC)ccc2n1-c1ccc(O)cc1,[Pd],C1CCOC1,CO,O=C[O-].[NH4+],,test
US20150210720A1,O=C(O)C(=O)CBr.O=C1COC2(CCN(C(=O)OCc3ccccc3)CC2)C(=O)C1>>O=C(O)c1coc2c1C(=O)C1(CCN(C(=O)OCc3ccccc3)CC1)OC2,,CO,O,O=C([O-])O.[Na+],,test
US05859030,Cc1c(SCCCCl)ccnc1CSc1nc2ccccc2[nH]1.Sc1nc2ccccc2[nH]1>>Cc1c(SCCCSc2nc3ccccc3[nH]2)ccnc1CSc1nc2ccccc2[nH]1,,CCO,O,[Na+].[OH-],,test
US05714487,CC1(CO)CC2CNCCN2C1.Fc1cnc(Cl)nc1>>CC1(CO)CC2CN(c3ncc(F)cn3)CCN2C1,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20110212937A1,COc1cc(Nc2nc3c(c(N4CC5(C4)OCCO5)n2)CCC3c2ccccc2)ccc1-n1cnc(Cl)c1>>COc1cc(Nc2nc3c(c(N4CC(=O)C4)n2)CCC3c2ccccc2)ccc1-n1cnc(Cl)c1,,CC(C)=O,,O,,test
US04283408,COC(=N)CCSCc1csc(NC(=N)N)n1.NS(N)(=O)=O>>N=C(N)Nc1nc(CSCCC(=N)NS(N)(=O)=O)cs1,,CO,,,,test
US04245120,O=C(Oc1ccccc1)c1cc([N+](=O)[O-])cc(C(=O)Oc2ccccc2)c1C(=O)Oc1ccccc1>>Nc1cc(C(=O)Oc2ccccc2)c(C(=O)Oc2ccccc2)c(C(=O)Oc2ccccc2)c1,[Pd],CN(C)C=O,,,,test
US20020055497A1,ClCC1CO1.FC(F)(F)c1ccc(-c2n[nH]cc2-c2ccncc2)cc1>>FC(F)(F)c1ccc(-c2nn(CC3CO3)cc2-c2ccncc2)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090111821A1,CS(=O)(=O)Cl.Cc1cccc(-c2cc(CO)no2)c1>>Cc1cccc(-c2cc(COS(C)(=O)=O)no2)c1,,ClCCl,,CCN(CC)CC,,test
US20090298744A1,CC1(C)OC(=O)C2(CC2)C(=O)O1.Nc1cccc(C(F)(F)F)c1>>O=C(O)C1CCN(c2cccc(C(F)(F)F)c2)C1=O,,ClCCl,,,,test
US20060025395A1,C=C/C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](CC[C@H](C)C[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)/C=C\[C@H](C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](C)/C=C/C=C\C(=O)OC)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C>>C=C/C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](CC[C@H](C)C[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)/C=C\[C@H](C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](C)/C=C/C=C\C(=O)O)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C,,C1CCOC1,CCO,[K+].[OH-],,test
US20110150834A1,CCOC(=O)Cn1c(-c2ccccc2)cc(Cc2ccccc2S(=O)(=O)N2CCOCC2)c1C.O=C(O)C(F)(F)F>>CCOC(=O)Cn1c(C)c(Cc2ccccc2S(=O)(=O)N2CCOCC2)c(C(=O)C(F)(F)F)c1-c1ccccc1,CN(C)c1ccncc1,ClCCl,,,,test
US20040058903A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(NCCc2ccccn2)cc1>>CC(C)(C)OC(=O)N(CCc1ccccn1)c1ccc([N+](=O)[O-])cc1,,C1CCOC1,,CCN(CC)CC,,test
US20030013708A1,COc1cc(N2CCCN(C)CC2)c2nc(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(OCOCC[Si](C)(C)C)c2c1>>COc1cc(N2CCCN(C)CC2)c2[nH]c(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(=O)c2c1,,CO,,Cl,[Na+].[OH-],test
US05135914,CC(C)CC(NC(=O)C(CCCCN)NC(=O)C(Cc1cccc2ccccc12)Cc1cccc2ccccc12)C(O)C(=O)OC(C)C.CN=C=S>>CNC(=S)NCCCCC(NC(=O)C(Cc1cccc2ccccc12)Cc1cccc2ccccc12)C(=O)NC(CC(C)C)C(O)C(=O)OC(C)C,,ClC(Cl)Cl,,,,test
US06239131B1,CC(C)(C)OC(=O)c1cccc(N)c1.N[C@@H]1CN(C2CCCCC2)c2ccccc2NC1=O.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)c1cccc(NC(=O)N[C@@H]2CN(C3CCCCC3)c3ccccc3NC2=O)c1,,C1CCOC1,,CCN(CC)CC,,test
US05510320,C#CCBr.Sc1nc[nH]n1>>C#CCSc1nc[nH]n1,,CO,,[K+].[OH-],,test
US20040132769A1,CC(=O)Cl.CCOC(=O)Nc1ccc2cc(O)ccc2c1>>CCOC(=O)Nc1ccc2cc(OC(C)=O)ccc2c1,,ClCCl,,CCN(CC)CC,,test
US20150038437A1,Cc1c(-c2ccc3c(c2)cc2n3CC(N)C2)nc(OCc2ccccc2)c(C(=O)OCc2ccccc2)c1OCc1ccccc1.Cl>>Cc1c(-c2ccc3c(c2)cc2n3CC(N)C2)[nH]c(=O)c(C(=O)O)c1O.Cl,[Pd],CO,,,,test
US20100168145A1,Cc1cc(C)c(S(=O)(=O)ON)c(C)c1.N#Cc1ccc2c(c1)C(=O)CC21CCCc2cncn21>>N#Cc1ccc2c(c1)NC(=O)CC21CCCc2cncn21,,CC#N,,,,test
US20040058978A1,CCCCN=C=O.Nc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1>>CCCCNC(=O)Nc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1,,C1CCOC1,,,,test
US04459150,Cl.ClCl.Nc1ccc(C(F)(F)F)c(Cl)c1>>Nc1c(Cl)cc(C(F)(F)F)c(Cl)c1Cl,,O,,,,test
US04348527,CCC(=O)OC(=O)CC.O=C(NC1=NN(c2ccc(C(=O)C(F)(F)F)cc2)CC1)C(F)(F)F>>CCC(=O)NC1=NN(c2ccccc2)CC1,CN(C)c1ccncc1,ClCCl,,,,test
US20070244117A1,Cc1nc(CCl)cs1.O=C1c2ccccc2C(=O)N1O>>Cc1nc(CON)cs1.Cl,,CN(C)C=O,,CCN(CC)CC,,test
US20080119518A1,COc1cccc(CCCO)c1CC1COC(C)(C)O1.CS(=O)(=O)Cl>>COc1cccc(CCCOS(C)(=O)=O)c1CC1COC(C)(C)O1,,C1CCOC1,,CCN(CC)CC,O,test
US20120022056A1,CCN(C(C)C)C(C)C.CN(C)C=O.Cc1ccc2c(N3CCN(CCc4cccc5c4OCc4c(C(=O)O)ncn4-5)CC3)cccc2n1>>CON(C)C(=O)c1ncn2c1COc1c(CCN3CCN(c4cccc5nc(C)ccc45)CC3)cccc1-2,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,test
US20080058378A1,CC(C)(C)OC(=O)N1CCC(N)CC1.COc1cc(F)c([N+](=O)[O-])c(F)c1>>COc1cc(F)c([N+](=O)[O-])c(NC2CCN(C(=O)OC(C)(C)C)CC2)c1,,CCN(C(C)C)C(C)C,CN(C)C=O,CCOC(C)=O,O,test
US20130299805A1,CCCC[Sn](Cl)(CCCC)CCCC.COc1ccc(-c2cccs2)cc1>>CCCC[Sn](CCCC)(CCCC)c1ccc(-c2ccc(OC)cc2)s1,,C1CCOC1,,[Li]CCCC,,test
US20140057899A1,C=C[C@@H](Cn1c(Br)c(-c2cnc3ccccc3c2)c2c(N)ncnc21)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@H]1CCc2c(-c3cnc4ccccc4c3)c3c(N)ncnc3n2C1,,C1CCOC1,,B1C2CCCC1CCC2,[Na+].[OH-],test
US20140100168A1,CCOC(=O)CBr.Cc1cc(C)cc(O)c1>>CCOC(=O)COc1cc(C)cc(C)c1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US05783591,CI.COc1ccc(C2(C)CNC(=O)O2)cc1OCC1CC1>>COc1ccc(C2(C)CN(C)C(=O)O2)cc1OCC1CC1,,C1CCOC1,,[K+].[OH-],,test
US05143928,CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O.O=C1CNC(=S)N1>>CC(C)(C)c1cc(C=C2NC(=S)NC2=O)cc(C(C)(C)C)c1O,,CC(=O)O,,O,CC(=O)[O-].[Na+],test
US05416089,CC1(O)CCCc2c1cc1c3c(cccc23)CC1>>CC1=CCCc2c1cc1c3c(cccc23)CC1,,CCOC(C)=O,Cc1ccccc1,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US20080021032A1,CC(C)(C)[Si](C)(C)OCCn1ccc(N)n1.O=C1CC[C@H](C[C@@H](C(=O)O)c2cccc(C(F)(F)F)c2)C1>>CC(C)(C)[Si](C)(C)OCCn1ccc(NC(=O)[C@H](C[C@H]2CCC(=O)C2)c2cccc(C(F)(F)F)c2)n1,,ClCCl,,Cc1cccc(C)n1,O=C(Cl)C(=O)Cl,test
US20030199689A1,CCOC(=O)c1cc2ccccc2[nH]1.O=C(CBr)Nc1ccc(Cl)cc1>>CCOC(=O)c1cc2ccccc2n1CC(=O)Nc1ccc(Cl)cc1,,CN(C)C=O,O,,,test
US20040007155A1,CCCCC(CC)CN.CCOC(=O)CC(C)=O.COC(=O)CC#N>>CCCCC(CC)Cc1ccc[nH]c1=O,,CO,,C1CCNCC1,Cl,test
US20040092582A1,CCOC(=O)C(C)(C)NC(=O)c1cccc(C2=NC(C)(C)Cc3c(CC#N)c(OC)c4c(c32)CC(C)(C)O4)c1.Cl>>COc1c(CC#N)c2c(c3c1OC(C)(C)C3)C(c1cccc(C(=O)NC(C)(C)C(=O)O)c1)=NC(C)(C)C2.Cl,,CCO,,[Na+].[OH-],,test
US03974284,CN.O=C1C2c3ccccc3C3C1C3c1ccccc12>>CNC1C2C3=CC=CCC3=C3C(c4ccccc42)C31,,CCO,CO,[BH4-].[Na+],,test
US20100137313A1,CCOP(=O)(CC(=O)OC)OCC.COc1ncc(-c2cnc(Nc3ccc(F)c(Cl)c3)nc2-n2ccc(C(F)(F)F)n2)cc1C=O>>COC(=O)/C=C/c1cc(-c2cnc(Nc3ccc(F)c(Cl)c3)nc2-n2ccc(C(F)(F)F)n2)cnc1OC,,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US20040235905A1,COc1ccc2c(c1)CCC(c1ccccc1)C2=O>>O=C1c2ccc(O)cc2CCC1c1ccccc1,,O,,Br,,test
US20030212119A1,CCCCN(CCCC)c1ccc(C=O)cc1.NCCOc1ccccc1.O=C(O)CCNC(=O)c1ccc2c(c1)nc(-c1cccc(Oc3cccc(C(F)(F)F)c3)c1)n2Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CCCCN(CCCC)c1ccc(-c2nc3cc(C(=O)NCCC(=O)O)ccc3n2CCOc2ccccc2)cc1,,CN1CCCC1=O,,,,test
US20130210844A1,CC(C)(C)Nc1ncnc2c(N)cccc12.Cc1ccc(CNC(=O)C(C)(C)C)c(C)c1C(=O)O>>Cc1ccc(CNC(=O)C(C)(C)C)c(C)c1C(=O)Nc1cccc2c(NC(C)(C)C)ncnc12,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20120077847A1,O=C(NCc1nnc(-c2ccc(OCc3ccccc3)cc2)o1)OCc1ccccc1>>NCc1nnc(-c2ccc(OCc3ccccc3)cc2)o1,,Br,CC(=O)O,CCOCC,,test
US20080269210A1,CS(=O)(=O)c1cccc(-c2cc3nc(-c4ccc(N)nc4)nc(N4CCOCC4)c3s2)c1.O=C=NS(=O)(=O)Cl>>CS(=O)(=O)c1cccc(-c2cc3nc(-c4ccc(NC(N)=O)nc4)nc(N4CCOCC4)c3s2)c1,,CC#N,,,,test
US20130079544A1,CC(=O)Cl.CCCCCCCC(=O)c1ccc(O)c(C(=O)O)c1>>CCCCCCCC(=O)c1ccc(OC(C)=O)c(C(=O)O)c1,,CC(C)=O,,O,c1ccncc1,test
US20070225352A1,ClCc1ccccn1.O=[N+]([O-])c1ccc2cc[nH]c2c1>>O=[N+]([O-])c1ccc2ccn(Cc3ccccn3)c2c1,,CN1CCCC1=O,,Cl,[Cl-].[NH4+],test
US20110034463A1,CCO.Cl.N#Cc1ccc(O)c([N+](=O)[O-])c1>>CCOC(=N)c1ccc(O)c([N+](=O)[O-])c1.Cl,,C1COCCO1,,,,test
US05116844,COC(=O)c1cc(C(C)C(O)(Cn2cncn2)c2ccc(F)cc2F)ccn1.NN>>CC(c1ccnc(C(=O)NN)c1)C(O)(Cn1cncn1)c1ccc(F)cc1F,,CC(C)O,,O,,test
US20090048269A1,Cc1ccc(O)c(C)n1.Clc1ccnc(Cl)c1>>Cc1ccc(Oc2ccnc(Cl)c2)c(C)n1,,CN(C)C=O,,[H-].[Na+],,test
US20070197478A1,CCOC(=O)c1ocnc1CC>>CCc1ncoc1C(=O)O,,CCOCC,,CCO,[Na+].[OH-],test
US04209519,COc1cc(NC(=O)CCCCCBr)c2nccc(C)c2c1.OCCN1CCNCC1>>COc1cc(NC(=O)CCCCCN2CCN(CCO)CC2)c2nccc(C)c2c1,,c1ccccc1,,O,,test
US04897392,O=C1Cn2c(c(Cl)c3ccccc32)-c2ccccc2N1.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>S=C1Cn2c(c(Cl)c3ccccc32)-c2ccccc2N1,,COCCOCCOC,,O,O=C([O-])O.[Na+],test
US20140148433A1,COC(=O)c1cnc(-c2nn(Cc3ccccc3F)c3ncccc23)nc1C>>Cc1nc(-c2nn(Cc3ccccc3F)c3ncccc23)ncc1C(=O)O,,C1CCOC1,,[Li+].[OH-],,test
US20010039344A1,Nc1ccccn1.O=C(O)C(CC1CCCC1)c1ccc(C(F)(F)F)cc1>>O=C(Nc1ccccn1)C(CC1CCCC1)c1ccc(C(F)(F)F)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20090156582A1,Cc1ccc(C(=O)Nc2cn(C3CCCCO3)nc2C(=O)NCC(F)(F)F)cn1>>Cc1ccc(C(=O)Nc2c[nH]nc2C(=O)NCC(F)(F)F)cn1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20090312327A1,C1CCC(P(C2CCCCC2)C2CCCCC2)CC1.CN(C(=O)c1ccc(Cl)c(Br)c1)C1CN(C(=O)C2CCN(C(=O)C3(C)CC3)CC2)CC1c1ccc(Cl)c(Cl)c1>>CN(C(=O)c1ccc(Cl)c(C2CC2)c1)C1CN(C(=O)C2CCN(C(=O)C3(C)CC3)CC2)CC1c1ccc(Cl)c(Cl)c1,,Cc1ccccc1,O,,,test
US20040192653A1,CNCCOC.COC(=O)[C@H](CCI)NC(=O)OC(C)(C)C>>COCCN(C)CC[C@H](NC(=O)OC(C)(C)C)C(=O)OC,,C1COCCO1,,CCN(CC)CC,,test
US20150197509A1,COC(=O)C1(NC(=O)OC(C)(C)C)CC1.Cl>>COC(=O)C1(N)CC1.Cl,,C1COCCO1,,,,test
US20150045378A1,CCOC(=O)CC(c1cc(OCc2cnc(-c3cc(OC)ccc3F)c(OCC(C)C)c2)ncn1)C1CC1>>COc1ccc(F)c(-c2ncc(COc3cc(C(CC(=O)O)C4CC4)ncn3)cc2OCC(C)C)c1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20010044140A1,CCCCCCCC/C=C\CCCCCCCC(=O)O.OCC(O)CO>>CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)CO,,O,,,,test
US20110009454A1,CCCCCI.Nc1ncccc1C(=O)NCc1cccc(O)c1>>CCCCCOc1cccc(CNC(=O)c2cccnc2N)c1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US04185115,CS(=O)(=O)Cl.OCCCCCCCCCCCc1ccccc1>>CS(=O)(=O)OCCCCCCCCCCCc1ccccc1,,CCN(CC)CC,,ClCCl,,test
US20130023541A1,NCCCN1CCCC1=O.O=Cc1c(F)cccc1Cl>>O=C1CCCN1CCCNCc1c(F)cccc1Cl,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160200709A1,CC(=O)OCCl.CC(C)CCN(CCC(C)C)c1cc(Cl)cc2cc([C@@H]3CCCN3)[nH]c12>>COC(=O)CN1CCC[C@H]1c1cc2cc(Cl)cc(N(CCC(C)C)CCC(C)C)c2[nH]1,,CN(C)C=O,,CCN(CC)CC,,test
US20030125370A1,Cc1[nH]c(C=O)c(C)c1CC(=O)N1CCOCC1.O=C1Cc2cc(S(=O)(=O)Cc3ccccc3)ccc2N1>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4ccccc4)cc32)c(C)c1CC(=O)N1CCOCC1,,CCO,,C1CCNCC1,,test
US20090029958A1,O=C(COCCc1cccc2c1CCCC2)N1CCC(O)CC1>>OC1CCN(CCOCCc2cccc3c2CCCC3)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100048604A1,CC(=O)c1c(Br)c(=O)oc2c3c4c(cc12)CCCN4CCC3.OB(O)c1ccccc1>>CC(=O)c1c(-c2ccccc2)c(=O)oc2c3c4c(cc12)CCCN4CCC3,,O,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20080221110A1,CC(C)(C)OC(=O)NC1CCN(CC2Cn3c(=O)ccc4ccc(Br)c2c43)CC1.N#C[Cu]>>CC(C)(C)OC(=O)NC1CCN(CC2Cn3c(=O)ccc4ccc(C#N)c2c43)CC1,,CN(C)C=O,,,,test
US20150133457A1,C=CC(=O)Cl.COCCN(C)c1ccc(Nc2nc(Oc3cccc(N)c3)c3cc[nH]c3n2)cn1>>C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N(C)CCOC)nc3)nc3[nH]ccc23)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US09133157B2,Brc1csc(Br)c1.CC(C)(C)S(=O)/N=C/CO[Si](C)(C)C(C)(C)C>>CC(C)(C)S(=O)NC(CO[Si](C)(C)C(C)(C)C)c1cc(Br)cs1,,CCOCC,ClCCl,[Li]CCCC,,test
US20120065199A1,CNC(=O)c1ccc2ncc(C(=O)O)c(Nc3ccc(OC)cc3)c2c1.Cc1oc(=O)oc1CBr>>CNC(=O)c1ccc2ncc(C(=O)OCc3oc(=O)oc3C)c(Nc3ccc(OC)cc3)c2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110166160A1,COC[C@H](C1CC1)n1cc(Cl)nc(Cl)c1=O.CO[C@H](Cn1cc(Cl)nc(Nc2cc(C)c(OC(F)F)nc2C)c1=O)C1CC1.Cc1cc(N)c(C)nc1OC(F)F>>CO[C@H](Cn1cc(Cl)nc(Nc2cc(C)c(OC(F)F)nc2C)c1=O)C1CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20110319379A1,COc1ccc(CNCc2ccc(OC)cc2OC)c(OC)c1.O=S(=O)(Cl)c1ccc(F)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2OC)S(=O)(=O)c2ccc(F)cc2)c(OC)c1,,ClCCl,,CCN(CC)CC,,test
US20090076046A1,CC(C)(C)OC(=O)Nc1nc(Cl)c(C=O)s1.O=S(=O)(c1ccccc1)n1cc(I)c2cc(Cl)cnc21>>CC(C)(C)OC(=O)Nc1nc(Cl)c(C(O)c2cn(S(=O)(=O)c3ccccc3)c3ncc(Cl)cc23)s1,,C1CCOC1,,CC(C)[Mg]Cl,[Cl-].[NH4+],test
US20090099224A1,CC(=O)OC(C)=O.CCC1(OC(=O)OCc2ccccc2)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2CC[Si](C)(C)CCCO>>CCC1(OC(=O)OCc2ccccc2)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2CC[Si](C)(C)CCCOC(C)=O,,ClCCl,,c1ccncc1,,test
US20040254161A1,NC(Cc1ccc(Oc2ccc3c(c2)S(=O)(=O)N=C2CCCN23)cc1)=NO.S=C(n1ccnc1)n1ccnc1>>O=S1(=O)N=C2CCCN2c2ccc(Oc3ccc(Cc4noc(=S)[nH]4)cc3)cc21,,CC#N,,C1CCC2=NCCCN2CC1,Cl,test
US20130336965A1,C[C@H]1C[C@@H](c2ccncc2NC(=O)OCc2ccccc2)C[C@@H](NC(=O)OCc2ccccc2)C1=O.OCCO>>C[C@H]1C[C@@H](c2ccncc2NC(=O)OCc2ccccc2)C[C@@H](NC(=O)OCc2ccccc2)C12OCCO2,,C1CCOC1,CCOC(C)=O,CCOCC,FB(F)F,test
US05310735,COc1ccc(CS[C@H]2C[C@@H](C(=O)N3CCN(CCO)CC3)N(C(=O)OCc3ccc([N+](=O)[O-])cc3)C2)cc1.O=C(Cl)OCc1ccc([N+](=O)[O-])cc1>>COc1ccc(CSC2CN(C(=O)OCc3ccc([N+](=O)[O-])cc3)C(CCOC(=O)OCc3ccc([N+](=O)[O-])cc3)(C(=O)N3CCNCC3)C2)cc1,CN(C)c1ccncc1,ClCCl,,CCOC(C)=O,,test
US20060252935A1,CN(C)CI.CN(C)C[c-]1cccc1.[Fe+2].c1cc[cH-]c1>>CN(C)Cc1ccc[c-]1CN(C)C.[Fe+2].c1cc[cH-]c1,,CCOCC,,[Li]CCCC,,test
US05623078,CC(C)(C)O.O=C(O)C1C2CN(Cc3ccccc3)CC21.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)NC1C2CN(Cc3ccccc3)CC21,,Cc1ccccc1,O,CCN(CC)CC,Cl,test
US20140038926A1,Brc1ccccn1.COC(=O)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(C(=O)OC(C)(C)C)C2>>CC(C)(C)OC(=O)N1CCC2=Cc3c(cnn3-c3ccc(F)cc3)C[C@]2(C(=O)c2ccccn2)C1,,CCOCC,,[Li]CCCC,,test
US20120083475A1,CC[Si](CC)(CC)c1[nH]c2cc(Cl)c(C)cc2c1CCN=[N+]=[N-]>>Cc1cc2c(CCN)c[nH]c2cc1Cl,,CO,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090239854A1,C=Cc1ccccc1.CCN1CCc2[nH]c3ccc(C)cc3c2C1>>CCN1CCc2c(c3cc(C)ccc3n2CCc2ccccc2)C1,,CN(C)C=O,,[H-].[Na+],,test
US08796467B2,COC(=O)CBr.Cc1cc(-c2c[nH]c(-c3ccccc3)n2)ccc1F>>Cc1cc(C(=O)CBr)ccc1F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080167305A1,CC(C)(C)COC(=O)Cl.Cc1ccc2c(N3CC[C@@H](N)C3)nc(Cl)nc2c1>>Cc1ccc2c(N3CC[C@@H](NC(=O)OCC(C)(C)C)C3)nc(Cl)nc2c1,,C1CCOC1,,CCN(CC)CC,,test
US05891909,Cc1cc(O)cc(OS(=O)(=O)c2ccccc2C(F)(F)F)c1.OCCCO>>Cc1cc(OCCCO)cc(OS(=O)(=O)c2ccccc2C(F)(F)F)c1,,C1CCOC1,CCCCCC,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20100075948A1,CCC(CC)(CC)CC1NC(C(=O)OC(C)(C)C)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.O=C(O)C(F)(F)F>>CCC(CC)(CC)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20130059883A1,CCOC(=O)C(=O)Cl.NC(=NO)c1cccc(C(=O)NCC2(c3nc(-c4ccccc4)cs3)CCOCC2)c1>>CCOC(=O)c1nc(-c2cccc(C(=O)NCC3(c4nc(-c5ccccc5)cs4)CCOCC3)c2)no1,,c1ccncc1,,,,test
US20140221310A1,C=Cc1cccc(F)c1O[Si](C)(C)C(C)(C)C>>CCc1cccc(F)c1O[Si](C)(C)C(C)(C)C,[Pd],CCOC(C)=O,,[H][H],,test
US20100292196A1,CCOC(=O)c1cnc2c(cnn2CC)c1Cl.NC1CCCCC1>>CCOC(=O)c1cnc2c(cnn2CC)c1NC1CCCCC1,,CC#N,,,,test
US20150337004A1,C=C(C)[C@@H]1CC[C@]2(C(=O)N3CCC[C@@H]3c3ncc(-c4cccnc4)[nH]3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CC1(C)CC(=O)OC1=O>>C=C(C)[C@@H]1CC[C@]2(C(=O)N3CCC[C@H]3c3ncc(-c4cccnc4)[nH]3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(=O)CC(C)(C)C(=O)O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,CN(C)c1ccncc1,CCOC(C)=O,Cc1ccccc1,,,test
US20100075978A1,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.CN1CCNCC1>>CN1CCN(C(=O)C2CCN(C(=O)OC(C)(C)C)CC2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030018032A1,Nc1ccccn1.O=Cc1cccc2ccccc12.[C-]#[N+]C(C)(C)C>>CC(C)(C)Nc1c(-c2cccc3ccccc23)nc2ccccn12,,[O-][Cl+3]([O-])([O-])O,,,,test
US04409214,C=CC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)C(NC(=O)C(=NOCC(=O)OC(C)(C)C)c3cccc(N)n3)[C@H]2SC1>>C=CC1=C(C(=O)O)N2C(=O)C(NC(=O)C(=NOCC(=O)O)c3cccc(N)n3)[C@H]2SC1,,CC(C)OC(C)C,,COc1ccccc1,O=C(O)C(F)(F)F,test
US05981533,CSC(NCc1ccc(N)cc1)=C(C#N)C#N.NN>>N#Cc1c(NCc2ccc(N)cc2)n[nH]c1N,,CO,,O,,test
US05041638,CC(C)(C)OC(=O)C1CCCCC1=O.COC(=O)c1ccc(SCl)cc1>>COC(=O)c1ccc(SC2(C(=O)OC(C)(C)C)CCCCC2=O)cc1,,ClCCl,,CCN(CC)CC,,test
US09283555B2,CC(C)(C)c1ccc(C#N)cc1.Cc1cccc(C)c1N>>Cc1cccc(C)c1NC(=N)c1ccc(C(C)(C)C)cc1,,O,,[Li]CCCC,,test
US20150080371A1,COc1cc(C)cc2cc(-c3c(C(=O)O)cn4ncnc(N)c34)sc12.O=C1CNCCN1>>COc1cc(C)cc2cc(-c3c(C(=O)N4CCNC(=O)C4)cn4ncnc(N)c34)sc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US04820719,CCCCCCCCCCCBr.COc1ccc(O)c(C=O)c1>>CCCCCCCCCCCOc1ccc(OC)cc1C=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040077669A1,CC#CCO.Fc1c(Cl)ncnc1Cl>>CC#CCOc1ncnc(Cl)c1F,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20150218150A1,Nc1cncc(-c2ccc(-c3ccc4c(c3)C(=O)NCC4)s2)c1.O=S(=O)(Cl)c1ccc(F)cc1F>>O=C1NCCc2ccc(-c3ccc(-c4cncc(NS(=O)(=O)c5ccc(F)cc5F)c4)s3)cc21,,CO,ClCCl,,,test
US20040127574A1,CC(C)(C)[Si](C)(C)Cl.CC1(C)CCC(O)c2c(CO)cccc2C1>>CC1(C)CCC(O)c2c(CO[Si](C)(C)C(C)(C)C)cccc2C1,,C1CCOC1,,CCN(CC)CC,O,test
US20110059943A1,CCN(N)C(=O)OC(C)(C)C.CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(N/C(=C/C(C)=O)SC)nc21>>CCn1nc(Nc2nc3c(cc(C(=O)N(C4CC4)C4CC4)n3CC)c3c2ncn3C)cc1C,,CC(=O)O,,O=CO,,test
US20110124618A1,CCOC(=O)c1cc(-c2ccc(F)c(C(F)(F)F)c2)n(-c2cccc(Cl)c2)n1>>O=C(O)c1cc(-c2ccc(F)c(C(F)(F)F)c2)n(-c2cccc(Cl)c2)n1,,C1COCCO1,O,[Li+].[OH-],,test
US20110053893A1,CCOC(=O)CCc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(O)cc3C)cc12.CCOP(=O)(OCC)C(F)(F)CCOCCBr>>CCOC(=O)CCc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(OCCOCCC(F)(F)P(=O)(OCC)OCC)cc3C)cc12,,CN(C)C=O,,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],test
US20080269524A1,CC[C@@](O)(c1cccc(OC)c1)[C@@H](C)CN(C)C.O=P(O)(O)O>>CC[C@@](OP(=O)(O)O)(c1cccc(OC)c1)[C@@H](C)CN(C)C,,CCO,,,,test
US20050245503A1,NC[C@H]1CCCO1.O=C(O)c1cnc(NNC(=S)NC2c3ccccc3CCc3ccnc(F)c32)c(Cl)c1>>O=C(NC[C@H]1CCCO1)c1cnc(NNC(=S)NC2c3cnccc3CCc3c(F)cccc32)c(Cl)c1,,CC(=O)N(C)C,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020086860A1,CC(=O)OC(C)=O.Clc1ccc2c(c1)CNCCN2>>CC(=O)C1CNc2ccc(Cl)cc2CN1,,C1CCOC1,,CCN(CC)CC,,test
US05136080,N.Nc1nc(Cl)c(-c2ccc(Cl)cc2Cl)c(Cl)n1>>Nc1nc(N)c(-c2ccc(Cl)cc2Cl)c(Cl)n1,[Cu],CCO,,,,test
US20120264734A1,CCN(c1cc(Br)c(F)c(C(=O)OC)c1C)C1CCOCC1>>CCN(c1cc(Br)c(F)c(C(=O)O)c1C)C1CCOCC1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20090163508A1,CC(C)(C)OC(=O)N1CCN(c2cccc(Br)c2)CC1.OB(O)Oc1cccc(F)c1F>>CC(C)(C)OC(=O)N1CCN(c2cccc(-c3cccc(F)c3F)c2)CC1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20060293352A1,CC(C)(C)OC(=O)COc1ccc(F)cc1Oc1ccc(N)cc1Cl.CCS(=O)(=O)Cl>>CCS(=O)(=O)Nc1ccc(Oc2cc(F)ccc2OCC(=O)O)c(Cl)c1,,c1ccncc1,,,,test
US20060247440A1,O=S(Cl)Cl.OCc1ccc(-n2cccn2)nc1>>ClCc1ccc(-n2cccn2)nc1,,ClCCl,,,,test
US20050130984A1,O=[N+]([O-])c1ccc2c(c1)OC(CO)CO2>>Nc1ccc2c(c1)OC(CO)CO2,[Pd],CO,,,,test
US20130210811A1,C[Si](C)(C)C(F)(F)F.O=C1CCC2(CC1)OCCO2>>OC1(C(F)(F)F)CCC2(CC1)OCCO2,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20130150364A1,N.O=C(O)[C@@H]1CC[C@@H](Nc2cc(-n3c(C(F)F)nc4ccccc43)nc(N3CCOCC3)n2)CC1>>NC(=O)[C@@H]1CC[C@@H](Nc2cc(-n3c(C(F)F)nc4ccccc43)nc(N3CCOCC3)n2)CC1,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20090247567A1,CNc1ccccc1Cl.O=C(Cl)c1cc2c(s1)-c1cc(F)ccc1OC2>>CN(C(=O)c1cc2c(s1)-c1cc(F)ccc1OC2)c1ccccc1Cl,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US06515014B2,NS(=O)(=O)c1ccc(-n2nc(CO)cc2-c2ccc(Cl)cc2)cc1.O=C(NOC(=O)Oc1ccccc1)Oc1ccccc1>>NS(=O)(=O)c1ccc(-n2nc(CN(OC(=O)Oc3ccccc3)C(=O)Oc3ccccc3)cc2-c2ccc(Cl)cc2)cc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070254931A1,CCOC(=O)CCc1ccc(CCCc2csc(NC(C)=O)n2)cc1>>CC(=O)Nc1nc(CCCc2ccc(CCC(=O)O)cc2)cs1,,C1COCCO1,,[Na+].[OH-],,test
US20150119385A1,COC(OC)c1nc2c(cc1CO[Si](C)(C)C(C)(C)C)CCCN2C(=O)Nc1cc(OC2CN3CCC2CC3)c(C#N)cn1>>N#Cc1cnc(NC(=O)N2CCCc3cc(CO)c(C=O)nc32)cc1OC1CN2CCC1CC2,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20030064991A1,BrCc1ccccc1.Cc1[nH]c2ccc(OCCCl)cc2c1C(=O)OCc1ccccc1>>Cc1c(C(=O)OCc2ccccc2)c2cc(OCCCl)ccc2n1Cc1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US06762189B1,CCOC(=O)c1cnc(SC)nc1Nc1ccc2cn[nH]c2c1.NC1CC1>>CSc1ncc(C(=O)NC2CC2)c(Nc2ccc3cn[nH]c3c2)n1,,O,,CO,,test
US05272163,CC(O)(C(=O)O)C(F)(F)F.Nc1ccc(C(=O)c2ccccc2)c(O)c1>>CC(O)(C(=O)Nc1ccc(C(=O)c2ccccc2)c(O)c1)C(F)(F)F,,CC(=O)N(C)C,,O,O=S(Cl)Cl,test
US20100063051A1,CC(C)(C(=O)Nc1nccs1)C(c1ccccc1)c1ccc(Br)cc1.COc1ccc(B(O)O)cc1>>COc1ccc(-c2ccc(C(c3ccccc3)C(C)(C)C(=O)Nc3nccs3)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050215605A1,Brc1cccc(Br)n1.CN(C)CCO>>CN(C)CCOc1cccc(Br)n1,,CCOCC,,[H-].[Na+],,test
US05552411,CCc1ccccc1S(=O)(=O)c1cc(NC(C)=O)c2ncccc2c1[N+](=O)[O-]>>CCc1ccccc1S(=O)(=O)c1cc(N)c2ncccc2c1[N+](=O)[O-],,Cl,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20080221127A1,CC(=O)O.N#CCc1cc(Cl)cc(Br)c1>>O=C(O)Cc1cc(Cl)cc(Br)c1,,CCOC(C)=O,O,O=S(=O)(O)O,,test
US20090186886A1,N#CC1CCN(CCCN2C(=O)c3ccccc3C2=O)C1>>N#CC1CCN(CCCN)C1,,CCO,,,,test
US20080318874A1,CC#N.CC[SiH](CC)CC.OC(c1ccc(C2CC2)cc1)c1ccccc1OCc1ccccc1>>C1=CCC(OCc2ccccc2)(c2ccccc2Cc2ccc(C3CC3)cc2)C=C1,,CC#N,,O,,test
US05021429,CN.CN(C)Cc1cccc(OCCCN)c1.CSC(=NS(C)(=O)=O)SC>>CNC(=NCCCOc1cccc(CN(C)C)c1)NS(C)(=O)=O,,CCO,,,,test
US20130102576A1,CN1CCN(CCN(c2ccc3c(c2)C(=O)N(CC(=O)OC(C)(C)C)C3=O)S(C)(=O)=O)CC1.O=C(O)C(F)(F)F>>CN1CCN(CCN(c2ccc3c(c2)C(=O)N(CC(=O)O)C3=O)S(C)(=O)=O)CC1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20050203153A1,COC(=O)c1ccc2nc(-c3cccc([N+](=O)[O-])c3)oc2c1>>O=C(O)c1ccc2nc(-c3cccc([N+](=O)[O-])c3)oc2c1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US06576656B1,CO.O=C1Nc2cc(I)cc(C(F)(F)F)c2C1(Br)Br>>O=C1Nc2cc(I)cc(C(F)(F)F)c2C1=O,,CO,,Br,O,test
US20150284370A1,Brc1ccc(Br)nc1.CN1CC(O)C1>>CN1CC(Oc2ccc(Br)cn2)C1,,C1CCOC1,O,CCOC(C)=O,[H-].[Na+],test
US20090197880A1,CS(=O)(=O)OCC1CCOC1.Oc1ccc(-c2cc(Cn3cc4nc(-c5cccc(F)c5F)nc-4cn3)on2)c(C(F)(F)F)c1>>Fc1cccc(-c2nc3cnn(Cc4cc(-c5ccc(OCC6CCOC6)cc5C(F)(F)F)no4)cc-3n2)c1F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020019383A1,CS(=O)(=O)OC1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1.N>>NC1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1,,CO,,,,test
US05998433,CC(C)(C)OC(=O)N1CCc2ccsc2C1.Cl>>Cl.c1cc2c(s1)CNCC2,,CO,,,,test
US20070149562A1,CN1C2CCC1CC(N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(Cn3cncn3)(C3CCCCC3)CC1)C2.Cl>>CN1C2CCC1CC(N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(Cn3cncn3)(C3CCCCC3)CC1)C2.Cl,,CC(C)O,ClCCl,,,test
US20110118239A1,O=C(Cl)c1ccccc1.O=C(O)[C@@H]1CCCN1>>O=C(O)C1CCCN1C(=O)c1ccccc1,,C1CCOC1,,O,O=C([O-])[O-].[K+].[K+],test
US20110039843A1,Fc1cnccc1-c1nc2cc3c(cc2o1)C(F)(F)OC3(F)F.OCC(F)(F)F>>FC(F)(F)COc1cnccc1-c1nc2cc3c(cc2o1)C(F)(F)OC3(F)F,,O,,CN(C)C=O,[H-].[Na+],test
US20040229949A1,CCOC(=O)C(Cc1ccc(OCCc2ccc(N)cc2)cc1)OCC.CS(=O)(=O)Cl>>CCOC(=O)C(Cc1ccc(OCCc2ccc(NS(C)(=O)=O)cc2)cc1)OCC,,ClCCl,,CCN(CC)CC,Cl,test
US20030153610A1,CC(C)n1c(=O)oc2cc(N3C[C@H](CN)OC3=O)ccc21.O=C(Cl)c1ccc(Cl)s1>>CC(C)n1c(=O)oc2cc(N3C[C@H](CNC(=O)c4ccc(Cl)s4)OC3=O)ccc21,,C1CCOC1,,CCN(CC)CC,Cl,test
US05610293,CC1CNCCNCCNCCNCCN1.[Cl-].[Cl-].[Mn+2]>>CC1(Cl)CNCCNCCNCCNCCN1Cl.[Mn+2],,CO,,,,test
US20130225561A1,CC(C)(C)OC(=O)N1CCNCC1.N#Cc1cccc2c1CCC2C=O>>CC(C)(C)OC(=O)N1CCN(CC2CCc3c(C#N)cccc32)CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US04739083,CC(=O)CC(=O)Nc1ccccc1Cl.CC(=O)O.CCCCN>>Cc1cc(=O)c(C(=O)Nc2ccccc2Cl)c(C)o1,CC(=O)O,,,Cc1ccccc1,O,test
US20110230458A1,CCCCc1nnc(C(=O)NCC2=CCN(C(=O)OC(C)(C)C)CC2)cc1-c1ccc(OC2CCCCC2)cc1.Cl.ClCCl>>CCCCc1nnc(C(=O)NCC2=CCNCC2)cc1-c1ccc(OC2CCCCC2)cc1.Cl.Cl,,C1COCCO1,ClCCl,,,test
US20110144105A1,COC(=O)c1cnc2c(c1)cc(C(=CC1CCCC1)OS(=O)(=O)c1ccc(C)cc1)n2S(=O)(=O)c1ccccc1.CSc1ccc(B(O)O)cn1>>COC(=O)c1cnc2c(c1)cc(C(=CC1CCCC1)c1ccc(SC)nc1)n2S(=O)(=O)c1ccccc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,CCOC(C)=O,O,O=C([O-])[O-].[Na+].[Na+],test
US20040186301A1,CCOC(=O)CC(CC(=O)OC(C)(C)C)C(=O)NCCc1ccc(-c2ccccc2)cc1>>CC(C)(C)OC(=O)CC(CC(=O)O)C(=O)NCCc1ccc(-c2ccccc2)cc1,,CO,,[Na+].[OH-],,test
US20050148656A1,CCOC(=O)[C@H](Cc1ccc(OCC(=O)N(CC)Cc2ccc(C(C)(C)C)cc2)cc1)OCC>>CCO[C@@H](Cc1ccc(OCC(=O)N(CC)Cc2ccc(C(C)(C)C)cc2)cc1)C(=O)O,,C1CCOC1,,Cl,[Li+].[OH-],test
US20130072490A1,O=C(O)[C@@H]1C[C@H]1c1ccccc1.[Li]C>>CC(=O)[C@@H]1C[C@H]1c1ccccc1,,CCOCC,,,,test
US20030130513A1,O=C1c2cccc(Br)c2CCC1(Br)Br>>O=C1c2cccc(Br)c2CCC1Br,,O,,,,test
US20120202828A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN1C(=O)[C@@H]2COC[C@]2(c2cc([N+](=O)[O-])ccc2F)N=C1N>>CN1C(=O)[C@@H]2COC[C@]2(c2cc([N+](=O)[O-])ccc2F)N=C1NC(=O)OC(C)(C)C,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20050119114A1,C=CCNCC=C.C=CC[Sn](CCCC)(CCCC)CCCC.ClB(Cl)Cl>>C=CCB(Cl)N(CC=C)CC=C,,CCCCCC,,CCN(CC)CC,,test
US20080132480A1,COC(=O)CBr.Oc1cc(Cl)ccc1I>>COC(=O)COc1ccc(Cl)cc1I,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US20060287308A1,CC(O)C1(F)CCN(C(=O)OCc2ccccc2)C1.CS(=O)(=O)Cl>>CC(OS(C)(=O)=O)C1(F)CCN(C(=O)OCc2ccccc2)C1,,ClCCl,,CCN(CC)CC,,test
US20130190330A1,COc1ccc(Cn2c(-c3ccc(Cl)cc3)n[nH]c2=O)cc1.O=S(=O)(Cl)c1ncn[nH]1>>COc1ccc(Cn2c(-c3ccc(Cl)cc3)nn(S(=O)(=O)c3ncn[nH]3)c2=O)cc1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04198514,COC(=O)CC(C#N)Cc1ccccc1Cl>>O=C1CC(Cc2ccccc2Cl)CN1,[Ni],,,,,test
US05084463,O=[N+]([O-])c1ccc(O)cc1.OCCCI>>O=[N+]([O-])c1ccc(OCCCI)cc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120245345A1,COC(=O)c1c(OC(C)=O)cnc2c1C(F)(F)C(=O)C=C2>>COC(=O)c1c(OC(C)=O)cnc2ccc(O)c(F)c12,[Pd],CO,,,,test
US20100041041A1,Br.CC(C)(C)c1ccccc1N>>CC(C)(C)c1ccccc1Br,[Cu],O,,O=N[O-].[Na+],,test
US20090197959A1,CCOC(=O)Cc1ccc(OC)c(-c2ccc(N)cc2CN(CC)C(=O)OCc2ccccc2)c1.CS(=O)(=O)Cl>>CCOC(=O)Cc1ccc(OC)c(-c2ccc(NS(C)(=O)=O)cc2CN(CC)C(=O)OCc2ccccc2)c1,,ClCCl,,CCN(CC)CC,,test
US20150018340A1,COCCl.O=C1CCCCC1>>O=C1CCCC[C@H]1CO,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090124596A1,CC(C)(C)OC(=O)NCCNC(=O)c1cccc(-n2c(=O)n([C@@H]3CC[C@H](NC(=O)c4cn5ccccc5n4)CC3)c(=O)c3cc(F)cnc32)c1>>NCCNC(=O)c1cccc(-n2c(=O)n([C@@H]3CC[C@H](NC(=O)c4cn5ccccc5n4)CC3)c(=O)c3cc(F)cnc32)c1,,C1COCCO1,,Cl,,test
US05438052,CC(C)(ON)C(=O)NO.Nc1nc(C(=O)C(=O)N[C@@H]2C(=O)N3C(C(=O)O)=C(CSc4nc(-c5ccccc5)ncc4-c4ccc(O)c(O)c4)CS[C@H]23)cs1>>CC(C)(O/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(CSc3nc(-c4ccccc4)ncc3-c3ccc(O)c(O)c3)CS[C@H]12)c1csc(N)n1)C(=O)NO,,CC(=O)N(C)C,,Cl,,test
US20100004208A1,COc1cc(C(=O)c2c(Br)oc3c(OC(C)=O)c(OC)ccc23)cc(OC)c1OC.Nc1cccnc1>>COc1cc(C(=O)c2c(Nc3cccnc3)oc3c(O)c(OC)ccc23)cc(OC)c1OC,,CC#N,O,,,test
US06642365B1,CO[C@H]1O[C@H](C(O)S(=O)(=O)c2ccc(C)cc2)[C@](O)(C(=O)c2ccccc2)[C@@](O)(C(=O)c2ccccc2)[C@@]1(O)C(=O)c1ccccc1.[N-]=[N+]=[N-]>>CO[C@H]1O[C@H](C(O)N=[N+]=[N-])[C@](O)(C(=O)c2ccccc2)[C@@](O)(C(=O)c2ccccc2)[C@@]1(O)C(=O)c1ccccc1,,CN(C)C=O,,O,,test
US20100240725A1,COc1ccc(C2(CCCN(C)C)OCc3cc(C#N)ccc32)cc1.Cl>>COc1ccc(C2(CCCN(C)C)OCc3cc(C#N)ccc32)cc1.Cl,,CCOCC,ClCCl,,,test
US20100249119A1,CN1CCNCC1.Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1Nc1ncc2nc(NC(=O)CCl)sc2n1>>Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1Nc1ncc2nc(NC(=O)CN3CCN(C)CC3)sc2n1,,C1CCOC1,O,CCN(CC)CC,CN(C)C=O,test
US20150111894A1,COc1cc(Br)ccc1C(=O)O.NCC1CC1>>COc1cc(Br)ccc1C(=O)NCC1CC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06169086A,CSSC.Fc1ncccn1.[Li]CCCC>>CSc1cccnc1F,,C1CCOC1,O,CC(C)NC(C)C,,test
US20020016347A1,Brc1cncc2ccccc12.Cc1ccccc1C(=O)c1ccc(N)cc1Cl>>Cc1ccccc1C(=O)c1ccc(Nc2cncc3ccccc23)cc1Cl,,C1COCCO1,,CC(C)(C)O[Na],,test
US20030232818A1,CCOC(=O)C=C(NC)NC.O=C(Cl)c1ccc(Cl)nc1Cl>>CCOC(=O)/C(=C\N(C)C)C(=O)c1ccc(Cl)nc1Cl,,Cc1ccccc1,,CCN(CC)CC,,test
US20150376130A1,COC(=O)c1cccnc1Nc1ccccc1>>O=C(O)c1cccnc1Nc1ccccc1,,CO,O,[K+].[OH-],,test
US06821980B1,CCOc1cc(Cc2cnc(N)nc2N)cc(OCC)c1-c1cccc(O)c1.COCCBr>>CCOc1cc(Cc2cnc(N)nc2N)cc(OCC)c1-c1cccc(OCCOC)c1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20080161269A1,CS(C)=O.C[Si](C)(C)c1cccc(C#Cc2cccc(Br)c2)c1.O>>C[Si](C)(C)c1cccc(C(=O)C(=O)c2cccc(Br)c2)c1,Cl[Pd]Cl,,,,,test
US20140350019A1,CCOC(=O)COc1ccc(F)c(NCc2cccc(-c3cccc(F)c3)c2)c1F>>O=C(O)COc1ccc(F)c(NCc2cccc(-c3cccc(F)c3)c2)c1F,,C1CCOC1,,O,[Na+].[OH-],test
US07138413B1,BrCc1ccc(CBr)cc1.CC(=O)c1ccc(O)cc1.CC1CCNCC1>>CC(=O)c1ccc(OCc2ccc(CN3CCC(C)CC3)cc2)cc1,,CC(C)=O,,[I-].[K+],,test
US20060040918A1,O=[N+]([O-])c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1>>Nc1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1,[Pd],CCO,,,,test
US06020366,O=C1C[C@H](NC(=O)C(F)(F)F)C(=O)O1.c1ccc2c(c1)oc1ccccc12>>O=C(C[C@H](NC(=O)C(F)(F)F)C(=O)O)c1ccc2oc3ccccc3c2c1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20130079313A1,CS(=O)(=O)Nc1cccc(S)c1.O=C(Oc1ccc([N+](=O)[O-])cc1)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1>>CS(=O)(=O)Nc1cccc(SC(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)c1,CN(C)c1ccncc1,ClCCl,,,,test
US06388127B1,Cl.Nc1ccc(Cl)c(Cl)c1.O=C(O)CS>>Cl.SCCNc1ccc(Cl)c(Cl)c1,,CCO,,Cc1ccccc1,,test
US05219860,C1=CC2(CCNCC2)c2ccccc21.CCCCI>>CCCCN1CCC2(C=Cc3ccccc32)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130217680A1,BrC(Br)(Br)Br.CC(C)(C)OC(=O)Cc1cnc(NC(=O)C(C)(C)C)cc1CCO>>CC(C)(C)OC(=O)Cc1cnc(NC(=O)C(C)(C)C)cc1CCBr,,ClCCl,O,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030236287A1,CC(C)(C)[Si](C)(C)Cl.Cc1cc(O)ccc1N=C=S>>Cc1cc(O[Si](C)(C)C(C)(C)C)ccc1N=C=S,,CN(C)C=O,O,c1c[nH]cn1,,test
US20080153852A1,Cc1cscc1Br.O=Cc1ccccc1B(O)O>>Cc1cscc1-c1ccccc1C=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US20070027071A1,C=CCC(C)O.CCCC[C@H](N)C(=O)OC.O=C(n1ccnc1)n1ccnc1>>C=CCCCOC(=O)N[C@@H](CCCC)C(=O)OC,,CCOCC,,CN(C)C=O,Cl,test
US05328911,CCCc1nc2c(Cl)ccnc2[nH]1.COC(=O)c1ccccc1-c1ccc(CBr)cc1>>CCCc1nc2c(Cl)ccnc2n1Cc1ccc(-c2ccccc2C(=O)OC)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20020016328A1,CCC(N)C(C)O.COC(=O)c1c(Cl)cc(C)nc1Oc1c(C)cc(Cl)cc1C>>CCC(Nc1cc(C)nc(Oc2c(C)cc(Cl)cc2C)c1C(=O)OC)C(C)O,,CN1CCCC1=O,,,,test
US05401736,Cc1cc(Cn2cnc3c2C[C@@H](C(=O)N(C)C)N(C(=O)C(c2ccccc2)c2ccccc2)C3)ccc1N.O=C(O)c1ccccc1C(=O)O>>Cc1cc(Cn2cnc3c2C[C@@H](C(=O)N(C)C)N(C(=O)C(c2ccccc2)c2ccccc2)C3)ccc1NC(=O)c1ccccc1C(=O)O,,CCOC(C)=O,,,,test
US05919799,NNC(=O)c1cccnc1.O=Cc1c(-c2cccc([N+](=O)[O-])c2)nc2sc3c(n12)CCCC3>>O=C(NN=Cc1c(-c2cccc([N+](=O)[O-])c2)nc2sc3c(n12)CCCC3)c1cccnc1,,CO,,O,[K+].[OH-],test
US20150368259A1,CCN=C=NCCCN(C)C.O=C(O)c1n[nH]cc1[N+](=O)[O-].On1nnc2ccccc21>>CN1CCN(Cc2ccc(NC(=O)c3n[nH]cc3[N+](=O)[O-])cc2)CC1,,CO,ClC(Cl)Cl,CN(C)C=O,Cl,test
US05276038,Nn1cnc2ccccc2c1=O.O=C=Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)Nn1cnc2ccccc2c1=O,,ClCCCl,,,,test
US04324786,O=C(Cl)C=Cc1ccccc1.OC1=Nc2ncccc2NN1>>O=C(C=Cc1ccccc1)N1NC(O)=Nc2ncccc21,,CC#N,,,,test
US20140113944A1,CC(C)(C)OC(=O)N[C@@]1(C(=O)OC(C)(C)C)CC(=O)[C@@H]2[C@H]1[C@H]2C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@]1(C(=O)O)CC(=O)[C@@H]2[C@H]1[C@H]2C(=O)O,,C1CCOC1,CCO,[Na+].[OH-],,test
US04447446,NCc1ccco1.O=C(Cl)c1cc(Cl)cc(Cl)c1>>O=C(NCc1ccco1)c1cc(Cl)cc(Cl)c1,,CCOC(C)=O,O,[Na+].[OH-],,test
US04968668,CC(=O)CCl.Cc1cc(C)cc(CCl)c1>>Cc1cc(C)cc(CC(C)(O)CCl)c1,,C1CCOC1,CCOCC,Cl,[Mg],test
US20040072832A1,CN(C)S(N)(=O)=O.Cc1cc2c(F)c(Oc3ncnn4cc(OCC5CO5)c(C)c34)ccc2[nH]1.ClCCl>>Cc1cc2c(F)c(Oc3ncnn4cc(OCC(O)CCNS(=O)(=O)N(C)C)c(C)c34)ccc2[nH]1,,CN(C)C=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US04436748,COc1ccc(S(=O)(=O)Cl)c(Cl)c1Cl>>COc1ccc(S)c(Cl)c1Cl,[Zn],ClCCl,,O=S(=O)(O)O,,test
US20110245249A1,O=Cc1cccc(Nc2ncc(Cl)c(NC3CC3)n2)c1.OCCO>>Clc1cnc(Nc2cccc(C3OCCO3)c2)nc1NC1CC1,,C1COCCO1,CCOC(C)=O,Cl,O=C([O-])O.[Na+],test
US20040267012A1,CC1(C)OB(c2ccc(C(=O)NCC3CC3)cc2)OC1(C)C.Cc1cc(C(=O)NC2CC2)cc(Br)c1C>>Cc1cc(C(=O)NC2CC2)cc(-c2ccc(C(=O)NCC3CC3)cc2)c1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(C)O,,O=C([O-])O.[Na+],,test
US20150274741A1,CSC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O.O=C(O)C(=O)O>>CSC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O.O=C(O)C(=O)O,,O,,CC(C)O,,test
US20050130989A1,CC(C)(C)OC(=O)N1CCN(c2cncc(OCc3ccccc3)c2)CC1.Cl>>Cl.c1ccc(COc2cncc(N3CCNCC3)c2)cc1,,C1COCCO1,,,,test
US20100311790A1,C#CCCCCl.O=C(NCc1cccc(O)c1F)c1ccc2ncccc2c1>>C#CCCCOc1cccc(CNC(=O)c2ccc3ncccc3c2)c1F,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20080081810A1,CCOC(=O)C1Cc2ccc(OC)cc2N1C1(Cc2cccc(Cl)c2)C(=O)Nc2cc(Cl)ccc21.N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O>>CCOC(=O)c1cc2ccc(Cl)cc2n1C1(Cc2cccc(Cl)c2)C(=O)Nc2cc(Cl)ccc21,,Cc1ccccc1,,,,test
US20150252038A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=C1CC(CO)CCN1Cc1cc(Cl)cc(Cl)c1>>Cc1ccc(S(=O)(=O)OCC2CCN(Cc3cc(Cl)cc(Cl)c3)C(=O)C2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20090306105A1,Clc1ncnc2cc(OCc3ccccc3)c(O[C@H]3CCOC3)cc12.Nc1ccc(F)c(Cl)c1>>Cl.Fc1ccc(Nc2ncnc3cc(OCc4ccccc4)c(O[C@H]4CCOC4)cc23)cc1Cl,,CC(C)O,,,,test
US05094938,CCCCCCCCCCCCOc1ccccc1C(=O)O.O=S(Cl)Cl>>CCCCCCCCCCCCOc1ccccc1C(=O)Cl,,ClCCl,,CN(C)C=O,,test
US20080171789A1,CC(=O)Cl.C[C@@H](OC(=O)[C@H](Cc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1)NC(=O)OC(C)(C)C)[C@@H](C)O>>CC(=O)O[C@H](C)[C@@H](C)OC(=O)[C@H](Cc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1)NC(=O)OC(C)(C)C,,ClCCl,,c1ccncc1,,test
US20130281657A1,CC(C)(C)OC(=O)[C@@H]1CCCN1c1ncc(C=O)s1>>O=Cc1cnc(N2CCC[C@H]2C(=O)O)s1,,ClCCl,,CCOCC,Cl,test
US20120258949A1,COC(=O)/C=C/c1ccc2c(c1)C(=O)NC1(CCCN(C)C1)O2>>CN1CCCC2(C1)NC(=O)c1cc(/C=C/C(=O)O)ccc1O2,,C1COCCO1,O,[Na+].[OH-],,test
US20110130406A1,COc1ccc(Nc2ncccc2C(=O)Nc2ccc(F)cc2)cc1F>>O=C(Nc1ccc(F)cc1)c1cccnc1Nc1ccc(O)c(F)c1,,ClCCl,,BrB(Br)Br,,test
US20040147513A1,CC(C)(Cc1ccc(OCCCC(=O)O)cc1)NCC(O)c1cc(OCc2ccccc2)cc2c1OCC(=O)N2>>CC(C)(Cc1ccc(OCCCC(=O)O)cc1)NCC(O)c1cc(O)cc2c1OCC(=O)N2,[Pd],CO,,CC(=O)O,,test
US20060106089A1,C=CS(=O)(=O)c1ccc(OC)c(S(=O)(=O)Nc2ccccc2NS(=O)(=O)c2cc3ccccc3s2)c1.CNC>>COc1ccc(S(=O)(=O)CCN(C)C)cc1S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1cc2ccccc2s1,,C1CCOC1,,,,test
US20080004271A1,NC(=O)c1sc2ncnc(-c3cccc(N)c3)c2c1N.O=C=Nc1cccc(C(F)(F)F)c1>>NC(=O)c1sc2ncnc(-c3cccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c3)c2c1N,,C1CCOC1,CS(C)=O,,,test
US20110028487A1,CN(C)S(=O)(=O)c1cc(F)ccc1CBr.[C-]#N>>CN(C)S(=O)(=O)c1cc(F)ccc1CC#N,,CN(C)C=O,,O,,test
US04302238,CC(C)(C(=O)Cl)C(=O)Cl.ONCc1ccccc1F>>CC1(C)C(=O)ON(Cc2ccccc2F)C1=O,,ClCCl,,c1ccncc1,,test
US05302593,BrCCCCCCCCBr.O=C1NC(=O)c2ccccc21>>O=C1NC(=O)c2c(CCCCCCCCBr)cccc21,,CN(C)C=O,,[K],,test
US06054412,CNN.O=Cc1ccc(Cl)cc1F>>CNN=Cc1ccc(Cl)cc1F,,CCO,,,,test
US20150065468A1,CC1(C)OB(c2ccc(CC(=O)Nc3cc(C4(C(F)(F)F)CC4)on3)cc2)OC1(C)C.COc1ccc2ncc(Cl)nc2c1>>COc1ccc2ncc(-c3ccc(CC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)cc3)nc2c1,,CC#N,O,O=C([O-])[O-].[Na+].[Na+],,test
US20070191341A1,COc1cc(CNC2CCCCNC2=O)ccc1OCCc1scnc1C.O=S(=O)(Cl)c1ccc(Cl)cc1>>COc1cc(CN(C2CCCCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)ccc1OCCc1scnc1C,,ClCCl,,CCN(CC)CC,,test
US20130184282A1,CCOC(=O)CCCCCCn1c(C2CC2)cc2nc(-c3ccccc3)c(-c3ccccc3)nc21>>O=C(O)CCCCCCn1c(C2CC2)cc2nc(-c3ccccc3)c(-c3ccccc3)nc21,,C1CCOC1,O,[Li+].[OH-],,test
US20060089394A1,CCCC[C@H](Sc1ccc(OCC(=O)OCC)c(C)c1)c1cccc(-c2ccc(C(F)(F)F)cc2)n1>>CCCC[C@H](Sc1ccc(OCC(=O)O)c(C)c1)c1cccc(-c2ccc(C(F)(F)F)cc2)n1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20100179150A1,CSC1CN(C(=O)OC(C)(C)C)CCC1=O.[NH4+]>>CS[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1N,,CO,,[BH3-]C#N.[Na+],,test
US20020007071A1,Cc1cccc2c1nc(COc1ccc(Cl)cc1)n2CCC(Cc1ccccc1)C(=O)O.NCCCN1CCCCC1>>Cc1cccc2c1nc(COc1ccc(Cl)cc1)n2CCC(Cc1ccccc1)C(=O)NCCCN1CCCCC1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20110105470A1,CC(C)(C)c1ccc(OC[C@@H]2CO2)cc1.O=C1C(=O)c2ccccc2C2=C1SCC1(CCNCC1)O2>>CC(C)(C)c1ccc(OC[C@@H](O)CN2CCC3(CC2)CSC2=C(O3)c3ccccc3C(=O)C2=O)cc1,,CCO,,,,test
US20090029987A1,Cc1cccc(O)c1C(=O)O.[Li]C>>CC(=O)c1c(C)cccc1O,,C1CCOC1,,CCOCC,,test
US20090318688A1,CI.CN(C=O)Cc1ccc([N+](=O)[O-])c(C(=O)O)c1>>COC(=O)c1cc(CN(C)C=O)ccc1[N+](=O)[O-],,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20060217372A1,N#Cc1ccc(O)c(Br)c1.O=Cc1ccc(Cl)nc1>>N#Cc1ccc(Oc2ccc(C=O)cn2)c(Br)c1,,CC(=O)N(C)C,,O,O=C([O-])[O-].[K+].[K+],test
US20020010176A1,CCOC(=O)CCC1CCc2cc3cccnc3nc2C1>>CCOC(=O)CCC1CCc2cc3c(nc2C1)NCCC3,[Pd],CCO,,,,test
US03951982,N#Cc1ccc(-c2ccc(F)cc2)[nH]c1=O.c1ccc(CN2CCNCC2)cc1>>N#Cc1ccc(-c2ccc(N3CCN(Cc4ccccc4)CC3)cc2)[nH]c1=O,,CS(C)=O,,,,test
US20150336950A1,CCOC(=O)c1ccc2c(n1)CC/C(=C\C1CCCC1)C2=O.N#Cc1ccc(NN)cc1Cl>>CCOC(=O)c1ccc2c(n1)CCC1C2=NN(c2ccc(C#N)c(Cl)c2)C1C1CCCC1,,CCO,,Cl,,test
US20070244336A1,CNCc1cccc2ccccc12.Cl/C=C/CCl>>CN(C/C=C/Cl)Cc1cccc2ccccc12,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070037868A1,C=CC[C@@H](C(=O)OC)N1CC[C@H](CC(C)C)C1=O>>C=CC[C@@H](C(=O)O)N1CC[C@H](CC(C)C)C1=O,,C1CCOC1,Cl,O,[Li+].[OH-],test
US20090048301A1,CCOC(=O)c1cccnc1Cl.OCc1ccc2c(c1)OCO2>>CCOC(=O)c1cccnc1OCc1ccc2c(c1)OCO2,,CN(C)C=O,,O,[H-].[Na+],test
US20110251173A1,CC(C)(C)[Si](C)(C)O[C@H]1CCN(Cc2ccc(-c3ccc(N4CCOc5ncnc(N)c5C4=O)cc3)c(Cl)c2)C1=O>>Nc1ncnc2c1C(=O)N(c1ccc(-c3ccc(CN4CC[C@H](O)C4=O)cc3Cl)cc1)CCO2,,C1COCCO1,,Cl,,test
US06277871B1,CCCCC(O)(CO)Cc1ccccc1.CS(=O)(=O)Cl>>CCCCC(O)(Cc1ccccc1)C(O)S(C)(=O)=O,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20060100246A1,COc1ccc(COc2cccc(OCC3CC3)c2-c2cc(C3CCN(C(=O)OC(C)(C)C)CC3)c3c(n2)NC(=O)C(C(N)=O)C3)cc1.Cl>>Cl.NC(=O)C1Cc2c(C3CCNCC3)cc(-c3c(O)cccc3OCC3CC3)nc2NC1=O,,C1COCCO1,,,,test
US20070299080A1,N#CCc1nc(Cl)cc(Cl)n1>>N#CCc1ncccn1,[Pd],CCOC(C)=O,CO,,,test
US20130158032A1,COc1cc(S(C)(=O)=O)ccc1[N+](=O)[O-]>>COc1cc(S(C)(=O)=O)ccc1N,[Pd],CCO,,,,test
US20140005213A1,CC(C)(C)OC(=O)N[C@@]1(C)CCN([C@@H](c2ccc(NN)nc2)C(F)(F)F)C1.CCOc1cc2nc(C=O)ccc2cc1F>>CCOc1cc2nc(/C=N/Nc3ccc([C@H](N4CC[C@](C)(NC(=O)OC(C)(C)C)C4)C(F)(F)F)cn3)ccc2cc1F,,CCO,,,,test
US20150218173A1,CCOC(=O)c1cc2c(Nc3ccc4[nH]ncc4c3)ncnc2[nH]1>>O=C(O)c1cc2c(Nc3ccc4[nH]ncc4c3)ncnc2[nH]1,,CCO,,[Na+].[OH-],,test
US20140256756A1,CC(C)c1nsc(N2CCC(N3CC[C@H](N)C3=O)CC2)n1.Clc1ncc(Br)cn1>>CC(C)c1nsc(N2CCC(N3CC[C@H](Nc4ncc(Br)cn4)C3=O)CC2)n1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090054435A1,COc1ccc(C(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c(O)c1.O=C1CCO1>>COc1ccc(C(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c(OCCC(=O)O)c1,,C1CCOC1,CN(C)C=O,Cl,CC(C)(C)[O-].[K+],test
US20020068702A1,CCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O>>CCC[C@@H](C=O)NC(=O)OCC1c2ccccc2-c2ccccc21,,CCOC(C)=O,CO,O=S(Cl)Cl,,test
US06117841,CC(C)(C)NC(=O)[C@@H](N)Cc1ccc(OCc2ccccc2)cc1.CC(C)C[C@@H](C(=O)O)N(C)C1CCCCC1>>CC(C)CC(C(=O)NC(Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)C1CCCCC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05627203,NO.O=C1c2sccc2-n2cccc21>>ON=C1c2sccc2-n2cccc21,,c1ccncc1,,Cl,,test
US20120114696A1,CCOC(=O)Cc1ccsc1.O=C1CCC(=O)N1Br>>CCOC(=O)Cc1ccsc1Br,,C1CCOC1,,,,test
US04134899,NC1CCCc2sccc21.O=C(Cl)CCl>>O=C(CCl)NC1CCCc2sccc21,,C1CCOC1,,CCN(CC)CC,Cl,test
US05559101,O=C(OC[C@@H]1O[C@H](n2ccc(=O)[nH]c2=O)[C@@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1)c1ccccc1>>O=c1ccn([C@H]2O[C@@H](CO)[C@H](O)[C@@H]2O)c(=O)[nH]1,,CO,N,,,test
US20070287696A1,BrCc1ccccc1.O=C(N[C@H]1CN[C@H](c2ccccc2)CN(CC2CC2)C1=O)N1CCC(n2cc(-c3ccccc3)[nH]c2=O)CC1>>O=C(N[C@@H]1CN(Cc2ccccc2)[C@@H](c2ccccc2)CN(CC2CC2)C1=O)N1CCC(n2cc(-c3ccccc3)[nH]c2=O)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120329818A1,CC(C)(C)OC(=O)N1CCC(C)(C(=O)Nc2cccc(-c3nnn[nH]3)c2)CC1>>CC1(C(=O)Nc2cccc(-c3nnn[nH]3)c2)CCNCC1,,CO,,Cl,,test
US20130102600A1,COC(=O)c1cc(N)ccn1.O=S=O.[N-]=[N+]=C(c1ccccc1)c1ccccc1>>COC(=O)c1cc(NS(=O)(=O)C(c2ccccc2)c2ccccc2)ccn1,,C1CCOC1,,,,test
US20070249686A1,CC(C)(C)OC(=O)CBr.Nc1ccc(Cl)cc1-c1ccccc1>>CC(C)(C)OC(=O)CNc1ccc(Cl)cc1-c1ccccc1,,CCO,,CC(=O)[O-].[Na+],,test
US06294527B1,CSc1cc(=O)c2ccc(C(=O)O)cc2s1>>CSc1cc(=O)c2ccc(CO)cc2s1,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US20050176796A1,CCOC(=O)c1nn(-c2ccc(OC)cc2)c2c1ccc1[nH]ncc12>>COc1ccc(-n2nc(C(=O)O)c3ccc4[nH]ncc4c32)cc1,,CO,,Cl,[Na+].[OH-],test
US20130310379A1,CCCC[Sn](CCCC)(CCCC)c1ccnnc1.COC(=O)c1ccc(Oc2cccc(Br)c2C#N)c(Cl)c1>>COC(=O)c1ccc(Oc2cccc(-c3ccnnc3)c2C#N)c(Cl)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,[Cl-].[Li+],,test
US20040167123A1,CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(NS(=O)(=O)N(C)C(=O)OCc4ccccc4)ccc3N2)c(O)c2cccnc21>>CNS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3cccnc3n(CCC(C)C)c1=O)N2,[Pd],CO,,,,test
US20060229305A1,CC(Cl)Cl.CC=C(C)c1cccc(Cl)c1OC.O=C([O-])C(=O)C(F)(F)F>>C=C(c1cccc(Cl)c1OC)C(C)C(O)(C(=O)OCC)C(F)(F)F,Cl[Fe](Cl)Cl,ClCCl,O,,,test
US07019104B1,O=C(C=Cc1ccccc1)OCCBr.O=C(O)c1ccc(C(=O)O)c(O)c1>>CCOC(=O)C=Cc1ccccc1.O=C(O)c1ccc(C(=O)O)c(O)c1,,CN(C)C=O,,,,test
US20160122318A1,CC[C@@H]1NCc2cc(C(=O)N[C@@H](CO)c3ccc(S(=O)(=O)CC)cn3)ccc21.O=C[C@@H]1CC[C@@H](C(F)(F)F)CC1>>CC[C@H]1c2ccc(C(=O)N[C@@H](CO)c3ccc(S(=O)(=O)CC)cn3)cc2CN1C[C@@H]1CC[C@@H](C(F)(F)F)CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20060264631A1,CCI.O=Cc1c[nH]c(=O)[nH]c1=O>>CCn1cc(C=O)c(=O)[nH]c1=O,,CN(C)C=O,,CO,[H-].[Na+],test
US04670447,CO.N#CN1CCC(c2nn(-c3ccccc3)c3ccccc23)CC1>>COC(=N)N1CCC(c2nn(-c3ccccc3)c3ccccc23)CC1,,CO,,C[O-].[Na+],,test
US20070161615A1,CC(=O)N[C@@H]1CCN(c2ccc([N+](=O)[O-])cc2)C1>>CC(=O)N[C@@H]1CCN(c2ccc(N)cc2)C1,[Pd],,,,,test
US04318854,O=C(c1ccccc1)c1cc(Cl)ccc1C#CCN1C(=O)c2ccccc2C1=O.O=CO>>O=C(CCN1C(=O)c2ccccc2C1=O)c1ccc(Cl)cc1C(=O)c1ccccc1,,ClCCl,,,,test
US06291530B1,C=CCc1cc(C(C)=O)ccc1OC(C)c1ccccc1.CCOP(=O)([O-])CC(=O)N(CC)CC>>C=CCc1cc(/C(C)=C/C(=O)N(CC)CC)ccc1OC(C)c1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US04495104,CC(=O)OCCCCCCCCCCCCCCCCCC(=O)Cl.COc1cc(C)cc(OC)c1OC>>COc1cc(C)c(C(=O)CCCCCCCCCCCCCCCCCO)c(O)c1OC,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20110046169A1,Cc1ccc(C(=O)Nc2ccc(Oc3ccc4nc(NC(=O)C5CC5)cn4c3)c(F)c2)c(=O)n1-c1ccccc1.Cc1ccc(S(=O)(=O)O)cc1>>Cc1ccc(C(=O)Nc2ccc(Oc3ccc4nc(NC(=O)C5CC5)cn4c3)c(F)c2)c(=O)n1-c1ccccc1.Cc1ccc(S(=O)(=O)O)cc1,,CCO,,O,,test
US20110082181A1,CS(N)(=O)=O.Cc1noc(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1[C@H](O)COCc1ccccc1>>Cc1noc(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)c1[C@H](O)COCc1ccccc1,CN(C)c1ccncc1,C1CCOC1,,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US20070185083A1,CNS(=O)(=O)NC.COc1ccc2c(c1)CC(c1ncc(CCC(=O)N3CCOCC3)o1)Cn1c-2c(C2CCCCC2)c2ccc(C(=O)O)cc21>>COc1ccc2c(c1)CC(c1ncc(CCC(=O)N3CCOCC3)o1)Cn1c-2c(C2CCCCC2)c2ccc(C(=O)NS(=O)(=O)N(C)C)cc21,,C1CCOC1,,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US20130059850A1,COC(=O)CBr.Clc1ccc(Sc2c(C3CCNCC3)[nH]c3ncccc23)cc1>>COC(=O)CN1CCC(c2[nH]c3ncccc3c2Sc2ccc(Cl)cc2)CC1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04874856,C/C=C\C1=C(C(=O)O)N2C(=O)C(NC(=O)/C(=N\O)c3csc(N)n3)[C@H]2SC1.CC(I)OC(=O)C(C)(C)C>>C/C=C\C1=C(C(=O)OC(C)OC(=O)C(C)(C)C)N2C(=O)C(NC(=O)/C(=N\O)c3csc(N)n3)[C@H]2SC1,,CCOC(C)=O,CN(C)C=O,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US06228870B1,N#Cc1cc(F)ccc1C1CCN(CCCNC(=O)N2C(=O)O[C@@H](COC3CCCCO3)[C@@H]2c2ccc(F)c(F)c2)CC1>>N#Cc1cc(F)ccc1C1CCN(CCCNC(=O)N2C(=O)O[C@@H](CO)[C@@H]2c2ccc(F)c(F)c2)CC1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US07186738B2,N#CCBr.O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(-c2c[nH]nn2)c(F)c1>>N#CCn1cc(-c2ccc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)nn1,,CN(C)C=O,O,[H-].[Na+],,test
US20020006948A1,O=[Cr](=O)=O.OCCCOc1ccc2nc(-c3ccccc3)n(-c3ccccc3)c2c1>>O=C(O)CCOc1ccc2nc(-c3ccccc3)n(-c3ccccc3)c2c1,,CC(C)=O,,O=S(=O)(O)O,,test
US20160108047A1,NC1=COC1.[C-]#[N+]/C(=C\N(C)C)C(=O)OCC>>CCOC(=O)c1cn(C2COC2)cn1,,CCCCO,,,,test
US20040082603A1,COc1ccc(CNC([PH2]=O)(c2ccccc2)c2ccccc2)cc1.COc1ccc(F)c(C(=O)Cl)c1>>COc1ccc(CN(C(=O)c2cc(OC)ccc2F)C([PH2]=O)(c2ccccc2)c2ccccc2)cc1,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20150162552A1,Clc1ccccc1Cl.O=[N+]([O-])c1ccccc1-c1ccc(-n2c3ccccc3c3ccc(-c4ccccn4)cc32)cc1>>c1ccc(-c2ccc3c4ccccc4n(-c4ccc5c(c4)[nH]c4ccccc45)c3c2)nc1,,Clc1ccccc1Cl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110053943A1,O=C(OC1C2CC3CC1CC(O)(C3)C2)N1CCC(c2ccncc2)C1.O=C(OO)c1cccc(Cl)c1>>O=C(OC1C2CC3CC1CC(O)(C3)C2)N1CCC(c2cc[n+]([O-])cc2)C1,,CO,ClCCl,,,test
US20130190332A1,COC(=O)c1cc(OC)c2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)n2c1.N>>COc1cc(C(N)=O)cn2c(-c3ccccc3)c(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)nc12,,CO,,,,test
US20130116243A1,FC(F)(F)CI.O=C1COc2nc(Br)c(-c3ccccc3)cc2N1>>O=C1COc2nc(Br)c(-c3ccccc3)cc2N1CC(F)(F)F,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20040198982A1,C[C@H]1C[C@@H](C(=O)NCC#N)N(c2cccc(Br)c2)C1.O=C1CCC(=O)N1Cl>>C[C@H]1C[C@@H](C(=O)NCC#N)N(c2cc(Br)ccc2Cl)C1,,CC(C)O,,,,test
US04232035,CC1OCSC1=NO.Cc1ccc(SSN(C)C(=O)F)cc1>>Cc1ccc(SSN(C)C(=O)ON=C2SCOC2C)cc1,,C1COCCO1,,CCN(CC)CC,,test
US20110251186A1,C=CC1(O)c2cc(OC)ccc2Oc2ccc(-c3cncnc3)cc21.NC(N)=S>>COc1ccc2c(c1)C1(CCSC(N)=N1)c1cc(-c3cncnc3)ccc1O2,,CC(=O)O,,Cl,,test
US04203988,CN(C)C(=O)Cl.Cc1cc(C)nc(N)c1>>Cc1cc(C)nc(NC(=O)N(C)C)c1,,Cc1ccccc1,,O,[H-].[Na+],test
US20040058965A1,CN(C)C=O.COCOCc1coc(-c2ccccc2)n1>>COCOCc1nc(-c2ccccc2)oc1C=O,,CCCCCC,CCOCC,Cl,[Li]CCCC,test
US20030109755A1,CCCCCC=O.O=C1CCCC1>>CCCCCC(O)C1CCCC1=O,,CCCCCC,,O,[Na+].[OH-],test
US04992433,CCOC(=O)c1ccc(OCCCC2CCN(c3ccc(Cl)nn3)CC2)cc1>>O=C(O)c1ccc(OCCCC2CCN(c3ccc(Cl)nn3)CC2)cc1,,CCO,,O,[K+].[OH-],test
US20150291613A1,CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(Br)cccc3nc2-1.O=C(n1ccnc1)n1ccnc1>>CC[C@@]1(OC(=O)n2ccnc2)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(Br)cccc3nc2-1,,C1CCOC1,ClCCl,,,test
US20150299171A1,CC(C)(C)OC(=O)NN=C1CCCCC1>>CC(C)(C)OC(=O)NNC1CCCCC1,[Pd],CO,,,,test
US05872131,Nc1c(Cl)cc(C(=O)O)c2c1CCO2.O=S(Cl)Cl>>Nc1c(Cl)cc(C(=O)Cl)c2c1CCO2,,ClC(Cl)Cl,,,,test
US20090124666A1,Cc1ncoc1-c1ccc(Br)cn1.ClC(Cl)(Cl)C(Cl)(Cl)Cl>>Cc1nc(Cl)oc1-c1ccc(Br)cn1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20130225583A1,CI.COc1ccc(CNc2nc(Cc3ccc(OC)c(OC)c3)n(-c3cc(C)nc(C)n3)n2)cc1>>COc1ccc(CN(C)c2nc(Cc3ccc(OC)c(OC)c3)n(-c3cc(C)nc(C)n3)n2)cc1,,CN(C)C=O,O,[H-].[Na+],,test
US20060160786A1,COc1ccc(N=C=S)cn1.Cc1ccccc1OC1CCNCC1>>COc1ccc(NC(=S)N2CCC(Oc3ccccc3C)CC2)cn1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20100152257A1,CCOC(=O)Cc1ccc(-c2ccc(-c3onc(C)c3NC(=O)OC(C)c3ccc(Cl)cc3F)cc2)cc1>>Cc1noc(-c2ccc(-c3ccc(CC(=O)O)cc3)cc2)c1NC(=O)OC(C)c1ccc(Cl)cc1F,,CO,O,Cl,[Li+].[OH-],test
US05688823,CC(=O)COc1ccc(CC2SC(=O)NC2=O)cc1.CN(CC(O)CN)c1ccccc1>>CC(COc1ccc(CC2SC(=O)NC2=O)cc1)NCC(O)CN(C)c1ccccc1,,CO,,[BH3-]C#N.[Na+],,test
US20120220589A1,COC(=O)c1ccc2[nH]c(=O)c(Cl)nc2c1.c1ccc2c(c1)CCCN2>>COC(=O)c1ccc2[nH]c(=O)c(N3CCCc4ccccc43)nc2c1,,CN1CCCC1=O,,,,test
US06337344B1,C[N+](C)(C)c1ccc(CNC(=O)c2cc3cc(OCc4ccccc4)ccc3n2Cc2cccc(C(=N)N)c2)cc1.O=C(O)C(F)(F)F.O=C([O-])C(F)(F)F>>C[N+](C)(C)c1ccc(CNC(=O)c2cc3cc(O)ccc3n2Cc2cccc(C(=N)N)c2)cc1.O=C(O)C(F)(F)F.O=C([O-])C(F)(F)F,[Pd],CCO,,O=C(O)C(F)(F)F,,test
US06897236B1,CCCCCC(=O)OCOC(=O)Oc1ccc([N+](=O)[O-])cc1.Cc1ccccc1C(=O)c1ccc(Nc2ccccc2N)cc1Cl>>CCCCCC(=O)OCOC(=O)Nc1ccccc1Nc1ccc(C(=O)c2ccccc2C)c(Cl)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,On1nnc2ccccc21,test
US20100160288A1,CC(C)(C)OC(=O)N1CCN(CCF)CC1.Cl>>Cl.FCCN1CCNCC1,,ClCCl,,C1COCCO1,,test
US04332948,CN(N)c1ccccc1.COc1ccc2ccccc2c1C=O>>COc1ccc2ccccc2c1C=NN(C)c1ccccc1,Cl,CCO,,,,test
US20080262042A1,Cc1occc1S(=O)(=O)n1cc(CN(C)C(=O)OC(C)(C)C)c(F)c1-c1cccnc1F.Cl>>CNCc1cn(S(=O)(=O)c2ccoc2C)c(-c2cccnc2F)c1F.Cl,,CCO,CCOC(C)=O,,,test
US04567270,CC(C)N(CCC1(c2ccccc2)CC2CCCCN2C1=O)C(C)C.CC(C)O.Cl>>CC(C)N(CCC1(c2ccccc2)CC2CCCCN2C1=O)C(C)C.Cl.O,,CC(C)O,,CCOCC,,test
US20050010052A1,C=CCNC(=O)OC(C)(C)C.CCI>>C=CCN(CC)C(=O)OC(C)(C)C,,CN1CCCC1=O,,[H-].[Na+],,test
US20030022881A1,C1CCOC1.O.[N-]=[N+]=NCCSc1ncn2ccsc12>>O=CNCCSc1ncn2ccsc12,[Pd],O,,Cl,[H][H],test
US20130237535A1,O=C(Cl)c1ccccc1.Oc1c(Br)ccc2cccnc12>>O=C(Oc1c(Br)ccc2cccnc12)c1ccccc1,,ClCCl,,c1ccncc1,,test
US20100280043A1,COc1ccc(Cn2nc(C(F)(F)F)c3c(N4CCN(C(=O)OC(C)(C)C)CC4)c(C4CC4)cnc32)cc1>>COc1ccc(Cn2nc(C(F)(F)F)c3c(N4CCNCC4)c(C4CC4)cnc32)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070173505A1,CC(C)(C)OC(=O)N1CC2CCNC2C1.CS(=O)(=O)c1nc(N)n2nc(-c3ccco3)nc2n1.ClCc1ccc(Cl)cc1>>Nc1nc(N2CCC3CN(Cc4ccc(Cl)cc4)CC32)nc2nc(-c3ccco3)nn12,,CC#N,,CCN(CC)CC,,test
US20080019915A1,O=C(O)C1(c2ccc3occc3c2)CC1>>O=C(O)C1(c2ccc3c(c2)CCO3)CC1,O=[Pt]=O,CO,,,,test
US20090247568A1,CC(C)(C)OC(=O)N1CCC(N(Cc2ccccc2)c2ccc3[nH]ccc3c2)CC1.CI.O=C(O)C(F)(F)F>>Cn1ccc2cc(N(Cc3ccccc3)C3CCNCC3)ccc21.O=C(O)C(F)(F)F,,CN(C)C=O,ClCCl,[H-].[Na+],,test
US04510154,CCCN.COC(=O)C1CSC(Cn2cncn2)(c2ccc(Cl)cc2Cl)N1>>CCCNC(=O)C1CSC(Cn2cncn2)(c2ccc(Cl)cc2Cl)N1,,CO,,,,test
US20090054411A1,COc1cc2ncc(C(N)=O)c(Nc3cccc(Cl)c3Cl)c2cc1N1CCN(C(=O)COC(C)=O)CC1>>COc1cc2ncc(C(N)=O)c(Nc3cccc(Cl)c3Cl)c2cc1N1CCN(C(=O)CO)CC1,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20090082434A1,COc1cc(Cl)cc2c1OC(C)(CO)C2.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1cc(Cl)cc2c1OC(C)(COS(=O)(=O)c1ccc(C)cc1)C2,CN(C)c1ccncc1,,,CCN(C(C)C)C(C)C,,test
US20160075657A1,COC(=O)c1cccc2c1CCN(Cc1ccc([C@H](C)NC(=O)OC(C)(C)C)cc1)C2>>COC(=O)c1cccc2c1CCN(Cc1ccc([C@H](C)N)cc1)C2,,C1COCCO1,,Cl,O=C([O-])O.[Na+],test
US20050182273A1,CC1(C)CCCC(C(C)(C)OC(=O)CCl)C1.CCC(=O)O>>CCC(=O)OCC(=O)OC(C)(C)C1CCCC(C)(C)C1,,CC(C)=O,,CCOCC,O=C([O-])[O-].[K+].[K+],test
US20080293951A1,CCCN(CCC)CCCCNCc1ccc(C#N)cc1.N#Cc1ccc(C=O)cc1>>CCCN(CCC)CCCCN(Cc1ccc(C#N)cc1)Cc1ccc(C#N)cc1,,CCO,,O=C([O-])O.[Na+],,test
US20140274688A1,CCOC(=O)/C=C/c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1.C[S+](C)(C)=O>>CCOC(=O)C1CC1c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1,,CS(C)=O,,[H-].[Na+],,test
US20160137639A1,CC(C)(C)CC1CC(c2onc(CCC(=O)OC(C)(C)C)c2C2CC2)C1>>CC(C)(C)CC1CC(c2onc(CCC(=O)O)c2C2CC2)C1,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US04654343,CCI.Cc1nnc2ccc(-c3cccc(NC(=O)C4CCC4)c3)nn12>>CCN(C(=O)C1CCC1)c1cccc(-c2ccc3nnc(C)n3n2)c1,,CN(C)C=O,,O,[H-].[Na+],test
US06018062,C[C@]12CC[C@@H]3c4ccc(OC5CCCCO5)cc4CC[C@H]3[C@@H]1CCC2=C(F)F>>C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=C(F)F,,CO,O,O=C(O)C(=O)O,,test
US20080194549A1,CCOC(=O)c1ccc(OC)c(COCCOC)c1>>COCCOCc1cc(C(=O)O)ccc1OC,,C1CCOC1,,[Na+].[OH-],,test
US20130116243A1,CCN1C(=O)COc2nc(-c3ccc(CNC(=O)OC(C)(C)C)cc3)c(-c3ccccc3)cc21>>CCN1C(=O)COc2nc(-c3ccc(CN)cc3)c(-c3ccccc3)cc21,,O=C(O)C(F)(F)F,,,,test
US20150210688A1,COCc1ncc(-c2cc(C(=O)OC)ccc2C)[nH]1.O=C1CCC(=O)N1Cl>>COCc1nc(Cl)c(-c2cc(C(=O)OC)ccc2C)[nH]1,,ClC(Cl)(Cl)Cl,,,,test
US04217130,COC(=O)[C@@H]1CCCN1.S=C(Cl)c1ccc(Cl)cc1>>COC(=O)[C@@H]1CC(Cl)CN1C(=S)c1ccccc1,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20090137609A1,CCOC(=O)Cc1ccc(-c2c(C)cc(C(CC)(CC)c3ccc(/C=C/C(O)(CC)CC)c(C)c3)cc2C)nc1>>CCC(O)(/C=C/c1ccc(C(CC)(CC)c2cc(C)c(-c3ccc(CC(=O)O)cn3)c(C)c2)cc1C)CC,,C1CCOC1,CO,[Na+].[OH-],[Cl-].[NH4+],test
US20110251178A1,O=C1CCC(=O)N1I.OCCc1cc(-c2ccc(F)cc2)n[nH]1>>OCCc1[nH]nc(-c2ccc(F)cc2)c1I,,CN(C)C=O,,,,test
US20070203155A1,BrBr.O=C(Cc1ccccc1)c1ccc(Br)cc1>>O=C(c1ccc(Br)cc1)C(Br)c1ccccc1,,CC(=O)O,,O,,test
US20150111870A1,C1CNC1.CC(C)Oc1c(Cl)nc2ccc(C(O)(c3ccc(Cl)cc3)c3cncn3C)cc2c1Cl>>CC(C)Oc1c(N2CCC2)nc2ccc(C(O)(c3ccc(Cl)cc3)c3cncn3C)cc2c1Cl,,CN(C)C=O,,O=C(O)C(F)(F)F,,test
US04885294,C[C@H]1CN(c2ccc([N+](=O)[O-])cc2)[C@@H](C)CN1.Clc1ccc(C2(Cn3cncn3)CO2)c(Cl)c1>>C[C@H]1CN(c2ccc(N)cc2)[C@@H](C)CN1CC(O)(Cn1cncn1)c1ccc(Cl)cc1Cl,,CCCCCO,,,,test
US20030055244A1,CCCCOC(=O)N[C@@H](CCC(=O)N1CCC2(CCN(c3ccncc3)CC2)C1)C(=O)OCC>>CCCCOC(=O)N[C@@H](CCC(=O)N1CCC2(CCN(c3ccncc3)CC2)C1)C(=O)O,,C1COCCO1,,[Li+].[OH-],,test
US20100292210A1,Clc1ccc2c(n1)O[C@H](c1ccccc1)CNC2.O=CCO>>OCCN1Cc2ccc(Cl)nc2O[C@H](c2ccccc2)C1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US07737166B2,Cc1c(I)c(Br)c2oc(C(C)(C)C)nc2c1C#N.O.c1ccccc1>>Cc1c(-c2ccco2)c(Br)c2oc(C(C)(C)C)nc2c1C#N,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,,,test
US20020128301A1,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.COc1ccc(COC(=O)C2CCC(O)CC2)cc1>>COc1ccc(COC(=O)C2CCC(OC(=O)[C@@H](NC(=O)OCc3ccccc3)C(C)C)CC2)cc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20130172302A1,O=C(CCl)c1ccccc1.O=C(O[C@H]1CN2CCC1CC2)C(c1ccsc1)N1CCCCC1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C(c1ccsc1)N1CCCCC1)C2)c1ccccc1.[Cl-],,CC#N,CCOC(C)=O,,,test
US20050043306A1,CCOC(=O)c1ccc(C)c(N)c1.NN>>Cc1ccc(C(=O)NN)cc1N,,CCO,,,,test
US05859007,COc1ccc(N(C(=O)CN2C(=O)C(Cc3nn(C(=O)OC(C)(C)C)c4ccccc34)C(=O)N(c3cccnc3)c3ccccc32)C(C)C)cc1>>COc1ccc(N(C(=O)CN2C(=O)C(Cc3n[nH]c4ccccc34)C(=O)N(c3cccnc3)c3ccccc32)C(C)C)cc1,,C1COCCO1,,Cl,,test
US20100280268A1,COC(=O)c1cc(Oc2ccc([N+](=O)[O-])c(Cc3ccccc3)c2)ccc1NS(=O)(=O)c1ccc(C)cc1>>COC(=O)c1cc(Oc2ccc(N)c(Cc3ccccc3)c2)ccc1NS(=O)(=O)c1ccc(C)cc1,[Pd],C1CCOC1,CO,[H][H],,test
US20110245224A1,C[C@H]1CN(c2c(C=O)cc3c(c2F)ONC3OC(=O)OC(C)(C)C)C[C@@H](C)O1>>C[C@H]1CN(c2c(C=O)cc3c(O)noc3c2F)C[C@@H](C)O1,,CO,,Cl,,test
US07179823B1,CCOC(=O)CCc1cn(Cc2ccc(O)cc2)cc1-c1ccccc1.ClCc1csc(-c2ccco2)n1>>CCOC(=O)CCc1cn(Cc2ccc(OCc3csc(-c4ccco4)n3)cc2)cc1-c1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US20150284382A1,NC1CC1.Nc1ccnc(Cl)n1>>Nc1ccnc(NC2CC2)n1,,CN1CCCC1=O,,,,test
US20090264650A1,N#C[Cu]C#N.O=C1C(Cc2ccc(Br)cc2Cl)CCN1C1CCCCC1>>N#Cc1ccc(CC2CCN(C3CCCCC3)C2=O)c(Cl)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US20150073172A1,CC(C)[C@H](N)C(=O)O.CCOC(=O)CC(C)=O.[K+]>>CCOC(=O)C=C(C)N[C@H](C(=O)[O-])C(C)C.[K+],,CC(=O)OC(C)C,,O,,test
US20070299068A1,CC(O)C1CC1.COCCOc1ccc2c(C#N)c(-c3ccc(N)cc3)n(C3CCC3)c2c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>COCCOc1ccc2c(C#N)c(-c3ccc(NC(=O)OC(C)C4CC4)cc3)n(C3CCC3)c2c1,,CC(Cl)Cl,,c1ccncc1,,test
US20110306587A1,Clc1ncc2ccccc2n1.Clc1nccnc1C1CNC1>>Clc1nccnc1C1CN(c2ncc3ccccc3n2)C1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20150031708A1,COc1ccc(B(O)O)cn1.Cc1ccc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1Cl>>COc1ccc(-c2nc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc2C)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US20110294664A1,CCOP(=O)(c1ccc(Cl)cc1)C1(C#N)CC1>>N#CC1(P(=O)(O)c2ccc(Cl)cc2)CC1,,ClC(Cl)Cl,,C[Si](C)(C)Br,,test
US20120202834A1,CCOC(=O)c1ccc(C(O)CCC(F)(F)F)cc1>>CCOC(=O)c1ccc(C(=O)CCC(F)(F)F)cc1,,CS(C)=O,ClCCl,CCN(CC)CC,,test
US20150031833A1,BrC(Br)(Br)Br.OCCOCCOCCOC(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(Br)OCCOCCOC(c1ccccc1)(c1ccccc1)c1ccccc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04053298,CNCCC=O.O=C=Nc1nnc(C(F)(F)F)s1>>CN(CCC=O)C(=O)Nc1nnc(C(F)(F)F)s1,,c1ccccc1,,,,test
US20110118230A1,CC(C)(C)O.O=C(O)c1cnc(Br)cc1I.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)Nc1cnc(Br)cc1I,,Cc1ccccc1,,CCN(CC)CC,,test
US06150373,O=C1c2ccccc2C(=O)N1Cc1ccc(N2C(=O)N(c3ccccc3Br)Cc3cnc(Nc4ccccc4)nc32)cc1>>NCc1ccc(N2C(=O)N(c3ccccc3Br)Cc3cnc(Nc4ccccc4)nc32)cc1,,CCO,,NN,O,test
US20160075647A1,CS(=O)(=NC(=O)C(F)(F)F)c1ccc([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)cc1>>CS(=N)(=O)c1ccc([C@@H](O)[C@H](N)CF)cc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04634768,COC(=O)c1cccc2c(=O)c(C)c(-c3ccccc3)oc12>>Cc1c(-c2ccccc2)oc2c(C(=O)O)cccc2c1=O,,CO,,[K+].[OH-],,test
US20120252780A1,C1CCOC1.CCN(CC)CC.FC(F)(F)c1cccc(-c2ccc3c(n2)NCC3)c1.Nc1ccccn1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC1CCN(C(=O)Nc2ccccn2)c2nc(-c3cccc(C(F)(F)F)c3)ccc21,,O,,,,test
US20050153979A1,CCc1cc2cc(F)ccc2n1C1CCN(Cc2ccccc2)CC1>>CCc1cc2cc(F)ccc2n1C1CCNCC1,,CO,,CC(=O)O,,test
US05362704,CCN(C(=O)Cl)C1CCCCC1.O=c1nn[nH]n1-c1ccccc1Cl>>CCN(C(=O)n1nnn(-c2ccccc2Cl)c1=O)C1CCCCC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090076020A1,CC(C)N1CCNCC1.O=C(O)/C=C/c1ccc(F)cc1>>CC(C)N1CCN(C(=O)/C=C/c2ccc(F)cc2)CC1,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,test
US04521426,Nc1ccc(Oc2cccc3ccccc23)nc1.O=C=NC(=O)c1c(F)cccc1F>>O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(Oc2cccc3ccccc23)nc1,,Cc1ccccc1,,,,test
US20120309760A1,CC(C)(C)OC(=O)c1ccc(F)cc1.NC1CCNCC1>>CC(C)(C)OC(=O)c1ccc(N2CCC(N)CC2)cc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130296375A1,COc1ccnc(C(=O)O)c1O.N[C@H]1COC[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)COC1=O>>COc1ccnc(C(=O)N[C@H]2COC[C@H](OCc3ccccc3)[C@@H](OCc3ccccc3)COC2=O)c1O,,ClCCl,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090197926A1,CCOC(=O)[C@H]1CC[C@@H](Oc2ccc(NC(=O)c3nnc(Nc4cc(F)c(F)cc4F)o3)c(N)c2)CC1>>CCOC(=O)[C@@H]1CC[C@H](Oc2ccc3nc(-c4nnc(Nc5cc(F)c(F)cc5F)o4)[nH]c3c2)CC1,,CC#N,,CC(=O)O,,test
US20100256188A1,Cn1c(Nc2cc(C#N)c(F)cc2Cl)nc2cc(C(=O)N[C@@H]3CC[C@@H](C(F)(F)F)CC3)c(OCC(F)F)cc21>>Cn1c(Nc2cc(CN)c(F)cc2Cl)nc2cc(C(=O)N[C@@H]3CC[C@@H](C(F)(F)F)CC3)c(OCC(F)F)cc21,[Ni],C1CCOC1,,,,test
US20150133432A1,CCOC(=O)c1cc(Br)nc2c1c(C)nn2C1CCCCO1.OB(O)c1ccc(OC2CCCCO2)cc1>>CCOC(=O)c1cc(-c2ccc(OC3CCCCO3)cc2)nc2c1c(C)nn2C1CCCCO1,,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US05712387,CC(=O)OC[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](C=O)OC(C)=O.F>>CC(=O)OC[C@H]1O[C@H](F)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,ClCCl,,c1ccncc1,,test
US07169926B1,N.O=c1c([N+](=O)[O-])c(Cl)ccn1Cc1ccccc1>>Nc1ccn(Cc2ccccc2)c(=O)c1[N+](=O)[O-],,C1CCOC1,,,,test
US20120245199A1,CO.O=C(c1c[nH]c2cnccc12)C(Cl)(Cl)Cl>>COC(=O)c1c[nH]c2cnccc12,,CO,,C[O-].[Na+],,test
US20090131457A1,Cn1nc(-c2cc(F)c(O)c(Br)c2)c2cnc(N)nc21.OCCBr>>Cn1nc(-c2cc(F)c(OCCO)c(Br)c2)c2cnc(N)nc21,,CN(C)C=O,CO,Cl,O=C([O-])[O-].[K+].[K+],test
US20080275053A1,CC(O)[Si](C)(C)C.O=C(O)c1ccccc1OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>C[Si](C)(C)CCOC(=O)Nc1ccccc1OCc1ccccc1,,Cc1ccccc1,,CCN(CC)CC,CCOC(C)=O,test
US20030166932A1,CCNc1ccc2c(c1)C(C)=CCC2(C)C.O=C(O)c1ccc(F)nc1>>CCN(c1ccc2c(c1)C(C)=CCC2(C)C)c1ccc(C(=O)O)cn1,,Cc1ccccc1,,CCOCC,,test
US20080287396A1,CCOP(=O)(OCC)C(CCCCOC(=O)c1cn(C2CC2)c2c(OC)c(N3C[C@@H]4[C@@H](CCCN4C(=O)OC(C)(C)C)C3)c(F)cc2c1=O)P(=O)(OCC)OCC>>COc1c(N2C[C@H]3NCCC[C@H]3C2)c(F)cc2c(=O)c(C(=O)OCCCCC(P(=O)(O)O)P(=O)(O)O)cn(C3CC3)c12,,ClCCl,,C[Si](C)(C)Br,,test
US20060229314A1,CCOC(=O)c1c(N2CCN(C(=O)c3cccs3)CC2)c2sccc2[nH]c1=O.O=C(CCl)c1ccccc1>>CCOC(=O)c1c(N2CCN(C(=O)c3cccs3)CC2)c2sccc2n(CC(=O)c2ccccc2)c1=O,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100048554A1,NCc1ccccc1.O=C1CCC2(CC1)OCCO2>>c1ccc(CN=C2CCC3(CC2)OCCO3)cc1,,ClCCl,,,,test
US04261992,COCc1cc2c(N=C=S)cccc2cn1.OCCC1Cc2ccccc2CN1>>COCc1cc2c(NC(=S)N3Cc4ccccc4CC3CCO)cccc2cn1,,CCO,,,,test
US20140066457A1,C#CC(O)c1ccccc1.CCOC(=O)/C(Cl)=N/O>>CCOC(=O)c1cc(C(O)c2ccccc2)on1,,CCOC(C)=O,O,O=C([O-])O.[Na+],,test
US05439909,CI.O=C(C1=COc2cc(O)ccc2O1)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1>>COc1ccc2c(c1)OC=C(C(=O)N1CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC1)O2,,CN(C)C=O,,[H-].[Na+],,test
US06514964B1,BrBr.CCOC(=O)CCCC(C)=O>>COC(=O)CCCC(=O)CBr,,CO,,,,test
US20090149439A1,Cc1cc(C(N)=O)ncc1C(Sc1ccc(F)cc1)c1cc(F)ccc1F.O=C(OO)c1cccc(Cl)c1>>Cc1cc(C(N)=O)ncc1C(c1cc(F)ccc1F)S(=O)c1ccc(F)cc1,,ClCCl,,,,test
US20130060041A1,C1=NNC(c2ccsc2)C1.CCN=C=S>>CCNC(=S)N1N=CCC1c1ccsc1,,CCO,,,,test
US04172195,OC[C@H](O)C(O)[C@H](O)CO>>O=C[C@H](O)[C@@H](O)[C@H](O)CO,,CO,,,,test
US20080004275A1,CCOC(=O)c1nccn1Cc1ccccc1>>CCOC(=O)c1ncc[nH]1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20120214762A1,Cc1nn(-c2ccnc(N)n2)c2cc(C#CC(C)(O)c3ncn(C4CCCCO4)n3)ccc12>>Cc1nn(-c2ccnc(N)n2)c2cc(C#CC(C)(O)c3nc[nH]n3)ccc12,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100240658A1,COCCO.N#Cc1cccc(CBr)c1>>COCCOCc1cccc(C#N)c1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,,test
US06399631B1,CCn1c2ccccc2c2cc(NC(=O)CCBr)ccc21.OC1(c2ccc(Cl)cc2)CCNCC1>>CCn1c2ccccc2c2cc(NC(=O)CCN3CCC(O)(c4ccc(Cl)cc4)CC3)ccc21,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,,test
US20020119962A1,NC(=O)NCC(=O)[O-].NO>>NC(=O)NCC(=O)NO,,C1COCCO1,,,,test
US04559177,CN(C)C=O.COc1cc(C)c(CCCCCCCCCCO)c(O)c1OC>>COC1=C(OC)C(=O)C(CCCCCCCCCCO)=C(C)C1=O,,c1ccncc1,,,,test
US20110166137A1,COc1ccc2cc(-c3ccnc(N(C)C)n3)cc(NC(=O)OC(C)(C)C)c2c1.Cl>>COc1ccc2cc(-c3ccnc(N(C)C)n3)cc(N)c2c1.Cl,,C1COCCO1,ClCCl,CCOCC,,test
US06894061B2,COc1ccc(S(=O)(=O)NC(C)c2ccccc2-c2ccc(F)cc2F)c(OC)c1>>COc1ccc(S(=O)(=O)N2c3cc(F)ccc3-c3ccccc3C2C)c(OC)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050227959A1,O=C(O)c1ccsc1.O=C1CCC(=O)N1Br>>O=C(O)c1csc(Br)c1,,CN(C)C=O,,O,,test
US20150299165A1,CC(C)(C)OC(=O)N1CS(=O)(=O)CC1C(N)=O.Cl>>Cl.NC(=O)C1CS(=O)(=O)CN1,,ClCCl,,C1COCCO1,,test
US20060205726A1,CN(C)C(=O)c1cc(Cl)ccc1[N+](=O)[O-].OCc1ccccc1>>CN(C)C(=O)c1cc(OCc2ccccc2)ccc1[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],,test
US20160244437A1,COC(=O)[C@H](Cc1ccc(C)c(Br)c1)NC(=O)[C@@H]1CC[C@@H](CNC(=O)OC(C)(C)C)CC1>>Cc1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)O)cc1Br,,C1CCOC1,,[Na+].[OH-],,test
US20120157487A1,CCCn1cnc(CSc2ccc(Cl)cc2N)c1.O=S(=O)(Cl)c1cc2ccccc2o1>>CCCn1cnc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)c1,,c1ccncc1,,,,test
US20080261941A1,CC(C)Oc1ccc(Oc2cccc(C=C3CCNCC3)c2)nc1.O=C(Nc1cccnn1)Oc1ccccc1>>CC(C)Oc1ccc(Oc2cccc(C=C3CCN(C(=O)Nc4cccnn4)CC3)c2)nc1,,CS(C)=O,O,CCN(CC)CC,,test
US20150225404A1,CI.c1cncc(-c2cc(OCc3ncc[nH]3)nc3c2CCCC3)c1>>Cn1ccnc1COc1cc(-c2cccnc2)c2c(n1)CCCC2,,CCOC(C)=O,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US20110257148A1,CCC(C)N.OC(CCl)(CCl)c1cc(F)cc(Cl)c1>>CCC(C)N1CC(O)(c2cc(F)cc(Cl)c2)C1,,CC#N,,O=C([O-])O.[Na+],,test
US20100035874A1,CC(Br)C(=O)Br.COc1cccc(Cl)c1>>COc1ccc(C(=O)C(C)Br)c(Cl)c1,,ClCCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20060183749A1,FC(F)(F)c1ccc2c(S)ccnc2c1.O=c1cc(COC2CCCCO2)occ1OCCCCCCCBr>>O=c1cc(COC2CCCCO2)occ1OCCCCCCCSc1ccnc2cc(C(F)(F)F)ccc12,,CN(C)C=O,O,[H-].[Na+],,test
US20130331579A1,C1CCCCC1.Cc1ccnc(C(C)(OS(C)(=O)=O)C(F)(F)F)c1>>Cc1ccnc(C(C)(C)C(F)(F)F)c1,,C1CCCCC1,,CCCCCC,,test
US04599357,CC(=O)SCCC(=O)Cl.COC(=O)C1Cc2ccccc2N1>>COC(=O)C1Cc2ccccc2N1C(=O)CCSC(C)=O,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US04015011,CC(Cc1cccc([N+](=O)[O-])c1)NC=O>>CC(Cc1cccc(N)c1)NC=O,[Ni],CO,,,,test
US05646173,CC=CCC1C(=O)c2cc(OC)ccc2C1(CC)CC.O=[O+][O-]>>CCC1(CC)c2ccc(OC)cc2C(=O)C1CC=O,,ClCCl,,CO,,test
US04264624,N#CC(O)c1cccc(Oc2ccc(F)cc2)c1.O=C(Cl)C(c1ccc(Cl)cc1)C1CC1>>N#CC(OC(=O)C(c1ccc(Cl)cc1)C1CC1)c1cccc(Oc2ccc(F)cc2)c1,,Cc1ccccc1,,c1ccncc1,,test
US20140329797A1,O=C(Cl)C(=O)Cl.O=C(O)c1cccc(Cn2nc(-c3nc(-c4ccc(OC(F)(F)F)cc4)no3)ccc2=O)c1>>O=C(Cl)c1cccc(Cn2nc(-c3nc(-c4ccc(OC(F)(F)F)cc4)no3)ccc2=O)c1,,ClCCl,,CN(C)C=O,,test
US20100234367A1,O=C1NC(=O)c2ccccc21.O[C@H]1CCC[C@@H](c2cccnc2)C1>>O=C1c2ccccc2C(=O)N1[C@H]1CCC[C@H](c2cccnc2)C1,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110015175A1,COc1cc(Nc2n[nH]c(C(CCCCCl)c3cc(F)cc(F)c3)n2)ccc1-n1cnc(Cl)c1>>COc1cc(Nc2nc3n(n2)CCCCC3c2cc(F)cc(F)c2)ccc1-n1cnc(Cl)c1,,CC(C)=O,,[I-].[Na+],,test
US20120202776A1,CC(C)S(=O)(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.Cc1cc(P(C)(C)=O)ccc1N>>Cc1cc(P(C)(C)=O)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1,,COCCO,,[Na+].[OH-],,test
US20120134934A1,CC(C)(C)OC(=O)NC(C(=O)O[C@H]1CN2CCC1CC2)c1ccc(Cl)cc1.O=C(CBr)c1ccccc1>>CC(C)(C)OC(=O)NC(C(=O)O[C@H]1C[N+]2(CC(=O)c3ccccc3)CCC1CC2)c1ccc(Cl)cc1.[Br-],,CCOC(C)=O,,,,test
US20030096812A1,C=O.CCOC(=O)N1CCC(N)C(C)C1.CO>>CCOC(=O)N1CCC(N(C)C)C(C)C1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20160046624A1,CC(C)Oc1cnc2c(c1C(O)c1ccc(Cl)cc1)c(=O)n(CCCOC1CCCCO1)c(=O)n2C.O=CO>>CC(C)Oc1cnc2c(c1Cc1ccc(Cl)cc1)c(=O)n(CCCOC=O)c(=O)n2C,[Zn],O=CO,,,,test
US20080039499A1,Nc1nc(C(=O)NC2CCN(Cc3ccccc3)CC2)cs1.O=C(Cl)c1cccc(F)c1>>O=C(Nc1nc(C(=O)NC2CCN(Cc3ccccc3)CC2)cs1)c1cccc(F)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20080096921A1,C1CCOC1.COC(=O)c1c(CBr)noc1C(C)C.OC1CCCC1>>CC(C)c1onc(COC2CCCC2)c1C(=O)OC1CCCC1,,C1CCOC1,,[H-].[Na+],,test
US20060211696A1,CCc1nc2c(Cl)nccn2c1C(=O)OC.OB(O)c1ccc(Cl)cc1Cl>>CCc1nc2c(-c3ccc(Cl)cc3Cl)nccn2c1C(=O)OC,,CO,Cc1ccccc1,,,test
US04016275,CCCc1cc(O)nc(S)n1.ClSC(Cl)(Cl)C(Cl)Cl>>CCCc1cc(O)ncn1.Cl,,COCCOC,,,,test
US20120252807A1,CI.CN(Cc1ccccc1)C(=O)C1CCN(C(=O)c2cc3ccccc3[nH]2)CC1>>CN(Cc1ccccc1)C(=O)C1CCN(C(=O)c2cc3ccccc3n2C)CC1,,C1CCOC1,O,[H-].[Na+],,test
US20040048868A1,COC(=O)c1ccc2[nH]c(-c3n[nH]c4ccccc34)nc2c1>>O=C(O)c1ccc2[nH]c(-c3n[nH]c4ccccc34)nc2c1,,C1CCOC1,O,[Na+].[OH-],,test
US03991045,CCCCCCCCCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCCCCCCCCC.Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1>>CCCCCCCCCCCCCCCCCCC(=O)Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1,,O,,C1COCCO1,,test
US20090247526A1,Nc1cc(Oc2c(F)cccc2F)c(Br)cn1.O=C(N=C=S)c1ccccc1>>O=C(NC(=S)Nc1cc(Oc2c(F)cccc2F)c(Br)cn1)c1ccccc1,,ClCCl,,,,test
US20050032838A1,CC(C)(C)OC(=O)NC1CCCCC1(C)O.Cl>>CC1(O)CCCCC1N.Cl,,C1COCCO1,,,,test
US05049572,CC(C)(C)c1cc(C(=O)Cl)cc(C(C)(C)C)c1O.Nc1ccc(CC(=O)O)cc1>>CC(C)(C)c1cc(C(=O)Nc2ccc(CC(=O)O)cc2)cc(C(C)(C)C)c1O,,COCCOC,,,,test
US20060089496A1,CC(=O)O.COc1ccc(N)c(C(=O)O)c1.NN.O=C1C(O)=C(C(=O)C(F)(F)F)CCN1c1ccc(I)cc1>>COC(=O)c1cc(OC)ccc1-n1nc(C(F)(F)F)c2c1C(=O)N(c1ccc(I)cc1)CC2,,Cl,O,O=N[O-].[Na+],,test
US20010031778A1,CC(C)(C)OC(=O)N1CCC(S)CC1.C[C@@H]1O[C@@]1(Cn1cncn1)c1ccc(F)cc1F>>CC(C)(C)OC(=O)N1CCC(S[C@@](C)(n2cncn2)[C@](C)(O)c2ccc(F)cc2F)CC1,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20130261123A1,NNC(=O)c1ccc(-c2ccc3cc(O)ccc3n2)cc1.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]nc(-c2ccc(-c3ccc4cc(O)ccc4n3)cc2)o1,,ClCCl,,CCOC(C)=O,,test
US20120115845A1,COC(=O)c1cc(-n2ccc(C)n2)ccc1Cl.N>>Cc1ccn(-c2ccc(Cl)c(C(N)=O)c2)n1,,CO,,,,test
US20090105253A1,CCNC(=O)c1ccc(N=[N+]=[N-])cc1.COC(=O)CC(=O)OC>>CCNC(=O)c1ccc(-n2nnc(C(=O)OC)c2O)cc1,,CO,,C[O-].[Na+],,test
US05053427,CC1(C)c2ccc(C#N)cc2C2OC21.[N-]=[N+]=[N-]>>CC1(C)c2ccc(C#N)cc2[C@@H](N=[N+]=[N-])[C@@H]1O,,CN(C)C=O,O,[Cl-].[NH4+],,test
US20110015173A1,Clc1cc(I)cc(Cl)n1.FC1(F)CNC1>>FC1(F)CN(c2cc(I)cc(Cl)n2)C1,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,Cl,test
US20140371209A1,COc1ccc2nc(CO)ncc2c1>>COc1ccc2nc(C=O)ncc2c1,,CCOC(C)=O,,,,test
US06251919B1,CC(C)CCN(c1ccc(OCC2CCCCC2)cc1)C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)CCN(c1ccc(OCC2CCCCC2)cc1)C1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US07183278B1,COc1ccnc(C)c1OCc1ccccc1.O=C(OO)c1cccc(Cl)c1>>COc1ccnc(CO)c1OCc1ccccc1,,ClCCl,,,,test
US20050009860A1,N#Cc1ccc(Br)cc1F.Sc1ccccc1>>N#Cc1ccc(Br)cc1Sc1ccccc1,,CN(C)C=O,,[Na+].[OH-],,test
US20100286390A1,CI.O=C1c2ccccc2C(=O)N1Cc1ccn[nH]c1=O>>Cn1nccc(CN2C(=O)c3ccccc3C2=O)c1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04894386,C=CCBr.CCCNC(=O)/C(C)=C/c1ccc2[nH]cc(Cc3ccc(C(=O)OC)cc3OC)c2c1>>C=CCn1cc(Cc2ccc(C(=O)OC)cc2OC)c2cc(/C=C(\C)C(=O)NCCC)ccc21,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20060252757A1,Nc1cccc(-c2c(-c3ccccc3)nnc3c(Cl)cccc23)c1.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)Nc1cccc(-c2c(-c3ccccc3)nnc3c(Cl)cccc23)c1,,CC#N,,,,test
US20140045746A1,CCOOCC1(F)CCOCC1>>OCC1(F)CCOCC1,,CO,,[BH4-].[Na+],,test
US20110152339A1,COc1ccc2c(c1)[nH]c1c(C)c(OCc3ccccc3)ccc12>>COc1ccc2c(c1)[nH]c1c(C)c(O)ccc12,[Pd],CO,,O=C[O-].[NH4+],,test
US06005116,COCOc1noc(-c2ccccc2)c1F>>Oc1noc(-c2ccccc2)c1F,,C1COCCO1,Cl,,,test
US20130225599A1,COC(=O)c1ccc(CC(=O)CC[C@@H](NC(=O)OC(C)(C)C)[C@@H](COc2ccccc2)O[Si](C)(C)C(C)(C)C)cc1>>COC(=O)c1ccc(CC2=N[C@@H]([C@@H](COc3ccccc3)O[Si](C)(C)C(C)(C)C)CC2)cc1,,ClCCl,,,,test
US20090054437A1,COc1cc(C(=O)COC(C)=O)cc([N+](=O)[O-])c1OC.NC(=O)c1ccc[n+]([O-])c1C(F)(F)F>>COc1cc(-c2coc(-c3ccc[n+]([O-])c3C(F)(F)F)n2)cc([N+](=O)[O-])c1OC,,Cc1ccccc1C,,CCOCC,FB(F)F,test
US20080045561A1,COc1cc2[nH]cc(-c3cc4c(Cl)c(F)cnc4n3S(=O)(=O)c3ccc(C)cc3)c2nc1OC>>COc1cc2[nH]cc(-c3cc4c(Cl)c(F)cnc4[nH]3)c2nc1OC,,CO,,[K+].[OH-],,test
US20150315198A1,BrBr.COc1cccc(C(=O)O)c1C>>COc1ccc(Br)c(C(=O)O)c1C,,O,,CC(=O)O,,test
US20110152242A1,COC(=O)c1scc(C)c1N.S=C=Nc1ccc(Cl)cc1>>Cc1csc2c(=O)n(-c3ccc(Cl)cc3)c(=S)[nH]c12,,CC#N,,,,test
US20060047001A1,NS(N)(=O)=O.O=Cc1csc2c(F)cccc12>>NS(=O)(=O)NCc1csc2c(F)cccc12,,CCO,,O,[BH4-].[Na+],test
US20110009390A1,BrCc1ccccc1.O=[N+]([O-])c1ccc(Cl)c(O)c1>>O=[N+]([O-])c1ccc(Cl)c(OCc2ccccc2)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120172599A1,CC1=C(C#N)C(=C(C#N)C#N)OC1(C)C.CCCCN(CCCC)c1ccc(C=Cc2ccc(C=O)s2)c(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1>>CCCCN(CCCC)c1ccc(C=Cc2ccc(C=CC3=C(C#N)C(=C(C#N)C#N)OC3(C)C)s2)c(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1,,C1CCOC1,CCO,C,O=C[O-].[NH4+],test
US05378728,CC(C)(C)C(=O)c1ccc(C(=O)Cl)cc1.CON>>CONC(=O)c1ccc(CC(C)(C)C=O)cc1,,C1CCOC1,,Cl,O=C([O-])[O-].[K+].[K+],test
US20130005707A1,CC(C)(C)OC(=O)Nc1cccc(CC2CCC(=O)C2)n1>>CC(C)(C)OC(=O)Nc1cccc(CC2CCC(O)C2)n1,,C1CCOC1,,[BH4-].[Na+],,test
US20130131016A1,C=C(c1cc(Cl)c(Cl)c(Cl)c1)C(F)(F)F.CC1(C)OB(O)c2cc(F)c(C(Cl)=NO)cc21>>CC1(C)OB(O)c2cc(F)c(C3=NOC(c4cc(Cl)c(Cl)c(Cl)c4)(C(F)(F)F)C3)cc21,,CN(C)C=O,,,,test
US20040259877A1,COCCl.O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cc(I)ccc1O>>COCOc1ccc(I)cc1C(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20140142114A1,CC(C)(C)OC(=O)N1CCC(Nc2ccc(C#N)c(C(F)(F)F)c2)CC1>>N#Cc1ccc(NC2CCNCC2)cc1C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160159808A1,CC(C)(O)[C@@H](NC(=O)c1cnn2ccc(Cl)nc12)c1ccc(OC(F)(F)F)cc1.Cc1c[nH]nn1>>Cc1cn(-c2ccn3ncc(C(=O)N[C@@H](c4ccc(OC(F)(F)F)cc4)C(C)(C)O)c3n2)nn1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070191289A1,CC(C)(C)C(=O)OC[C@H]1O[C@@H](Oc2n[nH]c3nccc(CCc4ccc(OCc5ccccc5)cc4)c23)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C.NC(=O)CBr>>CC(C)(C)C(=O)OC[C@H]1O[C@@H](Oc2nn(CC(N)=O)c3nccc(CCc4ccc(OCc5ccccc5)cc4)c23)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C,,CC(C)=O,,[I-].[Na+],O=C([O-])[O-].[Cs+].[Cs+],test
US20150376160A1,CON(C)C(=O)c1ccsc1C.C[Mg]Cl>>CC(=O)c1ccsc1C,,C1CCOC1,,[Cl-].[NH4+],,test
US20160108041A1,C[C@@H](CONC(=O)c1c2c(c(=O)n(C)c1Nc1ccc(I)cc1F)CCC2)O[Si](C)(C)C(C)(C)C>>C[C@H](O)CONC(=O)c1c2c(c(=O)n(C)c1Nc1ccc(I)cc1F)CCC2,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100311966A1,CC(C)(C)OC(=O)N1CCC(=O)C(OCCF)C1.NCc1ccccc1>>CC(C)(C)OC(=O)N1CC[C@H](NCc2ccccc2)[C@H](OCCF)C1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100056516A1,COC(=O)c1ccc2c(c1)CNCC2.O=c1cc(O)c2cccnc2n1OCc1ccccc1>>COC(=O)c1ccc2c(c1)CN(c1cc(=O)n(OCc3ccccc3)c3ncccc13)CC2,,CN(C)C=O,ClCCl,,,test
US05324747,CCCCCCCCCCc1cc(CCCCCCCCCC)cc(N(CC(=O)OCc2ccccc2)CC(=O)OCc2ccccc2)c1>>CCCCCCCCCCc1cc(CCCCCCCCCC)cc(N(CC(=O)O)CC(=O)O)c1,[Pd],C1CCOC1,,,,test
US20100168154A1,C[C@@H]1CC[C@@H](C(=O)NCCc2ccccc2)CC1>>C[C@@H]1CC[C@@H](C2NCCc3ccccc32)CC1,,O,,,,test
US20150133425A1,NC=O.O=C(O)C1CCc2c(sc3ncnc(Nc4ccc5[nH]ncc5c4)c23)C1>>NC(=O)C1CCc2c(sc3ncnc(Nc4ccc5[nH]ncc5c4)c23)C1,,CN(C)C=O,,C,C[O-].[Na+],test
US20110201605A1,Cc1nnc(N2CCC(=O)CC2)o1.Nc1ncn(Cc2cccc(Cl)c2)n1>>Cc1nnc(N2CCC(Nc3ncn(Cc4cccc(Cl)c4)n3)CC2)o1,,CC(=O)O,Cc1ccccc1,CCO,[BH4-].[Na+],test
US20110294777A1,CC(C)(C)OC(=O)N1CCc2cc(NC(=O)[C@@H]3CC[C@@H]4CN3C(=O)N4OCc3ccccc3)ccc2C1>>CC(C)(C)OC(=O)N1CCc2cc(NC(=O)[C@@H]3CC[C@@H]4CN3C(=O)N4O)ccc2C1,[Pd],CCOC(C)=O,CO,,,test
US20130109682A1,CC(C)(C)[Si](C)(C)Cl.O=[N+]([O-])c1cnccc1[C@@H]1OCC[C@H](CO)O1>>CC(C)(C)[Si](C)(C)OC[C@H]1CCO[C@@H](c2ccncc2[N+](=O)[O-])O1,,ClCCl,,c1c[nH]cn1,,test
US20090124609A1,CC(O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1Cl.COc1cnc2c(NCc3nnc4ccc(Cl)nn34)ccnc2c1>>COc1cnc2c(NCc3nnc4ccc(-c5ccc(C(C)O)c(Cl)c5)nn34)ccnc2c1,,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US06680317B2,CC(C)(C)[Si](C)(C)Cl.CN(C)S(=O)(=O)c1c(Cl)ccc(NC(=S)Nc2cccc(Cl)c2Cl)c1O>>CN(C)S(=O)(=O)c1c(Cl)ccc(NC(=S)Nc2cccc(Cl)c2Cl)c1O[Si](C)(C)C(C)(C)C,,C1CCOC1,,c1c[nH]cn1,,test
US20060235033A1,COc1cc2nccc(Oc3ccc(N)c(C(F)(F)F)c3)c2cc1OC.Cc1cnc(C(C)N)s1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)NC(C)c4ncc(C)s4)c(C(F)(F)F)c3)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20140121199A1,O=C(Cl)C(=O)Cl.O=C(O)c1cc(Cl)sc1Cl>>O=C(Cl)c1cc(Cl)sc1Cl,CN(C)C=O,ClCCl,,,,test
US20070078121A1,CCOC(=O)Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)cc1.N>>CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)n(-c2ccc(CC(N)=O)cc2)n1,,CO,,,,test
US05747424,CC(=O)C(C(=O)OC(C)(C)C)C(=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]>>CC(=O)CC(=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-],,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20140088101A1,COC(=O)c1cc(Br)c(=O)n(CC2CCCCC2)c1C.O=C1CCC(=O)N1Br>>COC(=O)c1cc(Br)c(=O)n(CC2CCCCC2)c1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US05773423,NCc1cccc(I)c1.Nc1nc(Cl)c2ncn(C3OC(CO)C(O)C3O)c2n1>>Nc1nc(NCc2cccc(I)c2)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1,,CCO,,CCN(CC)CC,Cl,test
US20120302610A1,CC(C)(C)OC(=O)CCNC(=O)c1ccc(-c2ccccc2CNc2ccc(-c3ccc(Cl)cc3)cc2)cn1>>O=C(O)CCNC(=O)c1ccc(-c2ccccc2CNc2ccc(-c3ccc(Cl)cc3)cc2)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070099990A1,Cc1c2c(c(C(O)c3ccccc3)c(C)c1NC(=O)CC(C)(C)C)OC(C)(C)C2>>Cc1c(Cc2ccccc2)c2c(c(C)c1NC(=O)CC(C)(C)C)CC(C)(C)O2,,CCCCCC,CCOC(C)=O,,,test
US04521430,CCN(C)CCN1C(=O)[C@H](O)[C@H](c2ccc(OC)cc2)Sc2ccccc21.O=C(Cl)c1ccc(Cl)cc1[N+](=O)[O-].O=C([O-])C(=O)[O-]>>CCN(C)CCN1C(=O)[C@H](OC(=O)c2ccc(Cl)cc2[N+](=O)[O-])[C@H](c2ccc(OC)cc2)Sc2ccccc21.O=C(O)C(=O)O,,ClCCl,,CCN(CC)CC,Cl,test
US20070043065A1,Cc1ccc(C(=O)NC2CC2)cc1-n1cnc2ccc(SCCN(C)C)cc2c1=O.Cc1ccc(S(=O)(=O)O)cc1>>Cc1ccc(C(=O)NC2CC2)cc1-n1cnc2ccc(SCCN(C)C)cc2c1=O.Cc1ccc(S(=O)(=O)O)cc1,,CCOC(C)=O,,,,test
US20110152321A1,CC[C@H](NC(=O)OC(C)(C)C)C(=O)NCCCc1cn(C(=O)OC(C)(C)C)c2ccccc12>>CC[C@H](N)C(=O)NCCCc1c[nH]c2ccccc12,,CCOCC,,Cl,ClCCl,test
US20110015173A1,CC(C)(CN)CNc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1.CS(=O)(=O)Cl>>CC(C)(CNc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1)CNS(C)(=O)=O,,CN(C)C=O,,CCN(CC)CC,O,test
US20050277652A1,C1CCN(C2CCNCC2)CC1.O=C(Nc1cc(Oc2ccc([N+](=O)[O-])cc2)ccn1)Oc1ccccc1>>O=C(Nc1cc(Oc2ccc([N+](=O)[O-])cc2)ccn1)N1CCC(N2CCCCC2)CC1,,C1CCOC1,,,,test
US20150005279A1,Cc1ccc(S(=O)(=O)Cl)cc1.N#Cc1ncc(Br)c2cc[nH]c12>>Cc1ccc(S(=O)(=O)n2ccc3c(Br)cnc(C#N)c32)cc1,,C1CCOC1,O,[H-].[Na+],,test
US20150250767A1,Cc1ccc(S(=O)(=O)n2ccc3c(C(C)(N)c4nc5cc(C#N)ccc5[nH]4)c(S(C)(=O)=O)cc(C)c32)cc1>>Cc1cc(S(C)(=O)=O)c(C(C)(N)c2nc3cc(C#N)ccc3[nH]2)c2cc[nH]c12,,CCO,,C,C[O-].[Na+],test
US04855295,CCOCC1CCCc2[nH]c3cnc(C(=O)OCC)c(COC)c3c21>>CCOCC1CCCc2[nH]c3cnc(C(=O)O)c(COC)c3c21,,CCO,Cl,[Na+].[OH-],,test
US20140206663A1,CC1C(=O)NN=C2COc3cc(F)c([N+](=O)[O-])cc3N21.Oc1ccccc1>>CC1C(=O)NN=C2COc3cc(Oc4ccccc4)c([N+](=O)[O-])cc3N21,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20060235030A1,CNC.Cc1c(F)cc(C(=O)O)cc1-c1nc(NCCN(C)C)nc2c1CNC(=O)N2c1c(F)cccc1F>>Cc1c(F)cc(C(=O)N(C)C)cc1-c1nc(NCCN(C)C)nc2c1CNC(=O)N2c1c(F)cccc1F,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090291988A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.N#CC1(c2ccc(Br)c(F)c2)CC1>>CC1(C)OB(c2ccc(C3(C#N)CC3)cc2F)OC1(C)C,,CN(C)C=O,O,CC(=O)[O-].[K+],,test
US06376726B1,Cc1ccc(C)cc1.O=[N+]([O-])O>>Cc1ccc(C)c([N+](=O)[O-])c1,,O,,,,test
US20110183985A1,COC[C@H]1CCCN1c1c(C(=O)N(C)OC)cc(Cl)c2cccnc12.C[Mg]Br>>COC[C@H]1CCCN1c1c(C(C)=O)cc(Cl)c2cccnc12,,C1CCOC1,,,,test
US06297235B1,COC(=O)c1nc(C)cs1.NN>>Cc1csc(C(=O)NN)n1,,CO,,O,,test
US20040082779A1,COc1ccc(Br)cc1S.N#Cc1ccccc1CBr>>COc1ccc(Br)cc1SCc1ccccc1C#N,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20060040984A1,C=CC#N.Clc1ccc(OC2CCN(CC3CCNCC3)CC2)cc1Cl>>N#CCCN1CCC(CN2CCC(Oc3ccc(Cl)c(Cl)c3)CC2)CC1,,O,,CCN(C(C)C)C(C)C,CN(C)C=O,test
US06121271,CC(=O)OC(C)=O.Cc1sc2cc3ccccc3c(-c3ccc(O)c(C(C)C)c3)c2c1C>>CC(=O)Oc1ccc(-c2c3ccccc3cc3sc(C)c(C)c23)cc1C(C)C,,c1ccncc1,,,,test
US20090186879A1,CCC(NC(=O)C(F)(F)F)c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl.CCI>>CCC(c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl)N(CC)C(=O)C(F)(F)F,,CN(C)C=O,,O,[H-].[Na+],test
US04110324,C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1C[C@@H](O)[C@@H]2O.c1ccncc1>>C1CCC(OC2CCCC2)C1,,c1ccncc1,,,,test
US20070117839A1,COC(=O)[C@@H]1CCC(=O)N1C(=O)OC(C)(C)C.Fc1ccc([Mg]Br)cc1F>>COC(=O)[C@H](CCC(=O)c1ccc(F)c(F)c1)NC(=O)OC(C)(C)C,,C1CCOC1,,O,,test
US06242439B1,C[C@@H]1C(=O)N([Si](C)(C)C(C)(C)C)[C@H]1Cc1ccccc1>>C[C@@H]1C(=O)N[C@H]1Cc1ccccc1,,CO,,[Cs+].[F-],,test
US05411980,CCCCc1nn(-c2ccc(OCc3ccccc3)cc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCCc1nn(-c2ccc(OCc3ccccc3)cc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,CC(=O)O,,,,test
US20150045368A1,O=C(O)C(c1ccccc1)C1(O)CCCC1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>O=C1NC(c2ccccc2)C2(CCCC2)O1,,CCCCCC,Cc1ccccc1,CCOC(C)=O,,test
US20030078268A1,Cc1ccc(S(=O)(=O)Cl)cc1.OC[C@H]1CCc2ccc3ncccc3c2O1>>Cc1ccc(S(=O)(=O)OC[C@H]2CCc3ccc4ncccc4c3O2)cc1,,c1ccncc1,,,,test
US05223525,CSSC.Nc1c(SC(F)(F)F)nc(Cl)n1-c1c(Cl)cc(C(F)(F)F)cc1Cl>>CSc1c(SC(F)(F)F)nc(Cl)n1-c1c(Cl)cc(C(F)(F)F)cc1Cl,,ClC(Cl)Cl,ClCCl,CC(C)(C)ON=O,,test
US20080221082A1,CC(Br)C(=O)O.O=C1CCNc2ccccc2N1>>CC(C(=O)O)N1C(=O)CCNc2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20090012311A1,COC(=O)Nc1ccc(C)c(F)c1.[O-][I+3]([O-])([O-])[O-]>>COC(=O)Nc1cc(F)c(C)cc1I,,CC#N,,O=S(=O)(O)O,,test
US20150126490A1,COC(=O)c1ccc(-c2nc(C3CCC4(CC3)OCCO4)cnc2N)cc1F>>COC(=O)c1ccc(-c2nc(C3CCC(=O)CC3)cnc2N)cc1F,,CC#N,O,Cl,[Na+].[OH-],test
US20060052374A1,CC(C)(C)OC(=O)N1CCCNCC1.CN(C)C=O.N#Cc1cccnc1Cl>>CC(C)(C)OC(=O)N1CCCN(c2ccccc2C#N)CC1,,CN(C)C=O,,O=C([O-])O.[K+],,test
US04229455,BrBr.O=c1c2ccccc2ccc2ccncc12>>O=c1c2ccccc2cc(Br)c2ccncc12,,CC(=O)O,,,,test
US20130066055A1,CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N1CCCCO1)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C.O=CCCC(=O)O>>CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N1CCCCO1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)CCCC(=O)O)C(C)C,,CO,,CC(=O)O,,test
US20110237596A1,Nc1cccn2ccnc12.O=C(Cl)Oc1ccccc1>>O=C(Nc1cccn2ccnc12)Oc1ccccc1,,CC#N,CCOC(C)=O,c1ccncc1,,test
US20080214544A1,COc1ccc(-c2cnc(SC)n(Cc3ccccc3)c2=O)cc1F.Nc1ccc(F)cc1>>COc1ccc(-c2cnc(Nc3ccc(F)cc3)n(Cc3ccccc3)c2=O)cc1F,,C1COCCO1,,Cl,,test
US20120302566A1,COC(=O)OC.Cc1cnc(O)c(C)c1Br>>Cc1cn(C)c(=O)c(C)c1Br,,O,,O=C([O-])[O-].[K+].[K+],,test
US20090181965A1,CCCI.COc1cccc(C2CCCCC2=O)c1>>CCCC1(c2cccc(OC)c2)CCCCC1=O,,CN(C)C=O,,CCO,[H-].[Na+],test
US05648373,N#CCCCCCCBr.O=c1[nH]c(-c2ccccc2)c(-c2ccccc2)n1-c1ccccc1>>N#CCCCCCCn1c(-c2ccccc2)c(-c2ccccc2)n(-c2ccccc2)c1=O,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04656269,CC(C)C[C@H](N)C(O)C(=O)O.CC(C)O.Cl>>CC(C)C[C@H](N)C(O)C(=O)OC(C)C.Cl,,CC(C)O,,c1ccccc1,,test
US06410592B1,OC1CCCCC1.Oc1ccc2c(c1)CCC(CNCCc1ccccc1)=C2c1ccccc1>>c1ccc(CCNCC2=C(c3ccccc3)c3ccc(OC4CCCCC4)cc3CC2)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090082403A1,C[N+](=O)[O-].O=Cc1ccc(SCc2ccccc2)cc1>>O=[N+]([O-])/C=C/c1ccccc1SCc1ccccc1,,CC(=O)O,,C,O=C[O-].[NH4+],test
US05312964,COC(=O)[C@@H]1[C@H](C(Br)C(=O)CBr)C1(C)C.O>>COC(=O)[C@@H]1[C@H](/C=C\C(=O)O)C1(C)C,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US05739132,Br.NC1Cc2ccc(C3=NNC(=O)CC3)cc2C1>>Br.NC1Cc2ccc(-c3ccc(=O)[nH]n3)cc2C1,,CCOCC,,CC(=O)O,,test
US20080318922A1,CCOC(=O)c1c(N)c(C#N)c(N2CCC[C@@H](NC(=O)OC(C)(C)C)C2)n1Cc1cc(F)ccc1Cl.CN=C=S>>Cn1c(=S)[nH]c2c(C#N)c(N3CCC[C@@H](NC(=O)OC(C)(C)C)C3)n(Cc3cc(F)ccc3Cl)c2c1=O,,c1ccncc1,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20150210630A1,CC(C)(C)OC(=O)NCC(=O)c1ncc(Cl)cc1Cl.NO>>CC(C)(C)OC(=O)NCC(=NO)c1ncc(Cl)cc1Cl,,CCO,,Cl,c1ccncc1,test
US20090111983A1,CSCC[C@@H](CO)NC(=O)C1(NC(=O)c2cc3ccccc3s2)CCCCC1>>CSCC[C@@H](C=O)NC(=O)C1(NC(=O)c2cc3ccccc3s2)CCCCC1,,CS(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US05114961,CCCOc1cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)O2)cc(S(=O)(=O)CCO)c1OCCC.CS(=O)(=O)Cl>>CCCOc1cc(C2COC(c3cc(OC)c(OC)c(OC)c3)C2)c(S(=O)(=O)CCS(C)(=O)=O)cc1OCCC,,ClCCl,c1ccncc1,CCCCCC,CCOC(C)=O,test
US20150232459A1,COc1ccc(Cn2nc(C(C)=O)c3cccnc32)cc1>>CC(=O)c1n[nH]c2ncccc12,,O=C(O)C(F)(F)F,,,,test
US20130324530A1,COc1ncc(-c2cc(N[C@@H]3CC[C@@H](N)CC3)ncc2Cl)cc1NCC1CCOCC1>>N[C@@H]1CC[C@@H](Nc2cc(-c3cnc(O)c(NCC4CCOCC4)c3)c(Cl)cn2)CC1,,O,,Cl,,test
US20140349350A1,COC(=O)CC(O)CC(=O)OC.N>>COC(=O)C[C@@H](O)CC(N)=O,,CCC(C)(C)O,,,,test
US20080182871A1,COc1cccc(C#N)c1.Cc1ccc(N(C)C)cc1C(=O)N(C)C>>COc1cccc(-c2cc3ccc(N(C)C)cc3c(=O)[nH]2)c1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20150352225A1,CN(Cc1cc2ccccc2n1CCC(=O)O)N(C)C(=O)OCC1c2ccccc2-c2ccccc21.Oc1c(F)c(F)c(F)c(F)c1F>>CN(Cc1cc2ccccc2n1CCC(=O)Oc1c(F)c(F)c(F)c(F)c1F)N(C)C(=O)OCC1c2ccccc2-c2ccccc21,,CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20140323485A1,Nc1cc(C(F)(F)F)c(Br)nc1C(=O)O.Nc1n[nH]c2nccnc12>>Nc1cc(C(F)(F)F)c(Br)nc1C(=O)Nc1n[nH]c2nccnc12,,CN(C)C=O,O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140256736A1,BrC(c1ccccc1)c1ccccc1.O=c1[nH]c2cc(Br)ccc2o1>>O=c1oc2ccc(Br)cc2n1C(c1ccccc1)c1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20130005707A1,CC(C)(C)OC(=O)Nc1cccc(CC(OS(C)(=O)=O)C2CCN(C(=O)OC(C)(C)C)CC2)n1>>CC(C)(C)OC(=O)Nc1cccc(C=CC2CCN(C(=O)OC(C)(C)C)CC2)n1,,CC(C)O,,O,[H-].[Na+],test
US20120108619A1,COC(=O)c1ccc2c(C#N)n[nH]c2c1>>N#Cc1n[nH]c2cc(C(=O)O)ccc12,,C1CCOC1,CO,[Li+].[OH-],,test
US20040138221A1,Cc1ccn(N2C(=O)c3ccccc3C2=O)c1-c1ccc(Cl)cc1Cl>>Cc1ccn(N)c1-c1ccc(Cl)cc1Cl,,CCO,,NN,O,test
US04304788,CC(O)c1ccc(-c2ccc(Cl)cc2)cc1.CCOC(=O)C(C)Br>>CCOC(=O)C(C)OC(C)c1ccc(-c2ccc(Cl)cc2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20040092529A1,CC(C)(C)OC(=O)CBr.C[C@H]1CN(C(=O)COc2ccc(Cl)cc2CO)[C@H](C)CN1Cc1ccc(F)cc1>>C[C@H]1CN(C(=O)COc2ccc(Cl)cc2COCC(=O)OC(C)(C)C)[C@H](C)CN1Cc1ccc(F)cc1,,C1CCOC1,,[H-].[Na+],,test
US05057531,CC(C)(C)C/C(=C/c1ccc(Cl)cc1)CO.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC/C(=C\c2ccc(Cl)cc2)CC(C)(C)C)cc1,,ClCCl,,CCN(CC)CC,,test
US20160060257A1,CNC(=O)ON1C(=O)CCC1=O.COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CC4CCCC(C3)N4)cc12>>CC(=O)[O-].CNC(=O)N1C2C=C(c3cc4c(-c5cc(F)ccc5OC)ccnc4[nH]3)CC1CCC2.[NH4+],,CN(C)C=O,,CCN(CC)CC,,test
US20060084645A1,CC(=O)OC(C)=O.CCOc1ccc(-c2cc(Cl)nc(N)n2)cc1>>CCOc1ccc(-c2cc(Cl)nc(NC=O)n2)cc1,,O,,,,test
US20090181942A1,C=CCBr.COc1cccc([C@H]2O[C@H](CC(=O)O)c3nnc(C(F)(F)F)n3-c3ccc(Cl)cc32)c1Cl>>C=CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2Cl)c2cc(Cl)ccc2-n2c1nnc2C(F)(F)F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US09373792B2,Brc1cccc(I)c1.OB(O)c1cc2c3ccccc3oc2c2ccccc12>>Brc1cccc(-c2cc3c4ccccc4oc3c3ccccc23)c1,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20070191395A1,CCOC(=O)C(C(C)=O)c1ccccc1.N#CCc1ncc[nH]1>>Cc1c(-c2ccccc2)c(=O)n2cc[nH]c2c1C#N,,O,,C,O=C[O-].[NH4+],test
US20050256158A1,CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(O)cc2)c2ccccc21.CCOC(=O)C1CCC(O)CC1>>CCOC(=O)C1CCC(Oc2ccc(C(=O)N3c4ccccc4[C@H](N(C(C)=O)c4ccc(Cl)cc4)C[C@@H]3C)cc2)CC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04673746,COc1cccc(Cl)c1Cl.O=C(Cl)c1ccoc1>>COc1ccc(C(=O)c2ccoc2)c(Cl)c1Cl,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20070117793A1,NCC1CCN(C(=O)OCc2ccccc2)CC1.O=BC=NC(Cc1ccccc1)C1CO1>>O=BC=NC(Cc1ccccc1)C(O)CNCC1CCN(C(=O)OCc2ccccc2)CC1,,CC(C)O,,,,test
US20160185727A1,COC[C@@H]1CC[C@@H](O)CC1.N#Cc1c([N+](=O)[O-])cccc1[N+](=O)[O-]>>COC[C@@H]1CC[C@@H](Oc2cccc([N+](=O)[O-])c2C#N)CC1,,C1CCOC1,,O,[H-].[Na+],test
US20090088419A1,CCc1nc(CC(C)(C)C)c(CNC(=O)OC(C)(C)C)c(-c2ccc(C)cc2)c1CC(=O)O.Cc1oc(=O)oc1CCl>>CCc1nc(CC(C)(C)C)c(CNC(=O)OC(C)(C)C)c(-c2ccc(C)cc2)c1CC(=O)OCc1oc(=O)oc1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020045644A1,Cc1cc(=O)c(-c2ccc(F)cc2F)c(-c2ccc(S(C)(=O)=O)cc2)o1.O=[Se]=O>>CS(=O)(=O)c1ccc(-c2oc(C=O)cc(=O)c2-c2ccc(F)cc2F)cc1,,C1COCCO1,,,,test
US20020052369A1,O=C1Cc2ccccc2N1.O=Cc1cc2cc(CCCN3CCCC3)ccc2[nH]1>>O=C1Nc2ccccc2C1=Cc1cc2cc(CCCN3CCCC3)ccc2[nH]1,,CCO,,C1CCNCC1,,test
US20120329785A1,CN1CCC(N(C)c2ccc(N)cc2)CC1.COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1>>COc1ccc2nc(Nc3ccc(N(C)C4CCN(C)CC4)cc3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US20080312211A1,Cc1[nH]c2c(=O)n(C3CCN(C(=O)OCc4ccccc4)CC3)c(=O)[nH]c2c1C#N>>Cc1[nH]c2c(=O)n(C3CCNCC3)c(=O)[nH]c2c1C#N,[Pd],CO,,,,test
US20100310512A1,COC(=O)NC(C(=O)N1CCCC1C(=O)Nc1ccc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)cc1)C(C)C.COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(Br)cc2)[nH]1)C(C)C>>COC(=O)NC(C(=O)N1CCCC1C(=O)Nc1ccc(-c2ccc(-c3ccc(-c4cnc(C5CCCN5C(=O)C(NC(=O)OC)C(C)C)[nH]4)cc3)cc2)cc1)C(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20050048601A1,C1CCOC1.CCOC(C)=O.COC(=O)c1ccco1.COc1ccc([Mg]Br)c(OC)c1.O=C([O-])O>>COc1ccc(C(O)(c2ccco2)c2ccc(OC)cc2OC)c(OC)c1,,C1CCOC1,CCOC(C)=O,Cl,,test
US20150353553A1,C[C@@H](Nc1nc(C#N)nc2ncn(Cc3ccc(C(F)(F)F)cc3N)c12)C1CCC1.O=C1OC(=O)c2ccccc21>>C[C@@H](Nc1nc(C#N)nc2ncn(Cc3ccc(C(F)(F)F)cc3N3C(=O)c4ccccc4C3=O)c12)C1CCC1,,O,,CC(=O)O,,test
US20160016948A1,C1CC2CNCC1O2.Nc1ccnc(Cl)n1>>Nc1ccnc(N2CC3CCC(C2)O3)n1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20010047094A1,C=CCOC(=O)Cl.O=C(O)C1CCNCC1>>C=CCOC(=O)N1CCC(C(=O)O)CC1,,ClCCl,,[Na+].[OH-],,test
US20160095858A1,CC(C)(C)c1ccc(C#N)c(Cl)n1.CCOC(C)=O.[OH-]>>CC(C)(C)c1ccc(C(=O)O)c(Cl)n1,,CC(C)O,CCOC(C)=O,O,,test
US20050288340A1,COC(=O)c1cc(S(=O)(=O)Cl)ccc1C(C)C.Cc1sc(-c2ccc(C(F)(F)F)cc2)nc1CCN>>COC(=O)c1cc(S(=O)(=O)NCCc2nc(-c3ccc(C(F)(F)F)cc3)sc2C)ccc1C(C)C,,CC(C)=O,O,CN(C)C=O,O=C([O-])O.[Na+],test
US05216001,COC(CBr)OC.NCCN1CCC(c2cn(-c3ccc(F)cc3)c3cc(Cl)ccc23)CC1>>COC(C)(NCCN1CCC(c2cn(-c3ccc(F)cc3)c3cc(Cl)ccc23)CC1)OC,,C1COCCO1,,[I-].[K+],,test
US20060030613A1,Fc1cc2cc[nH]c2cc1F.O=C=O>>O=C(O)c1c(F)c(F)cc2cc[nH]c12,,C1CCOC1,CCCCCC,O,[Li]CCCC,test
US20150320702A1,NC1=CC(=O)c2ccccc2C1=O.O=C(Cl)c1cccc(Cl)c1>>O=C(NC1=CC(=O)c2ccccc2C1=O)c1cccc(Cl)c1,,C1CCOC1,,[H-].[Na+],,test
US20070010524A1,CCOC(=O)Cn1nc(I)c2cccnc21>>O=C(O)Cn1nc(I)c2cccnc21,,C1CCOC1,,CO,[Li+].[OH-],test
US04325946,CO[C@H]1C[C@H](NC(=O)C(F)(F)F)[C@](C)(O)[C@H](C)O1>>C[C@@H]1O[C@@H](O)C[C@H](NC(=O)C(F)(F)F)[C@]1(C)O,,CC(=O)O,O,,,test
US20050107409A1,CC(C)(C)OC(=O)NCC1CCCCN1C(=O)c1ccc2c(Cl)ncnc2c1.N=C(N)c1cccc(CN)c1>>N=C(N)c1cccc(CNc2ncnc3cc(C(=O)N4CCCCC4CN)ccc23)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20100004128A1,CCOC(=O)C(F)(F)Cl.CCOC(=O)c1nnn(Cc2ccc(OC)cc2)c1O>>CCOC(=O)c1nnn(Cc2ccc(OC)cc2)c1OC(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110098297A1,CCOC(=O)CC1CN=C(c2cc3cc(Oc4ccc(S(C)(=O)=O)nc4)c(F)c(OCCOC)c3[nH]2)S1>>COCCOc1c(F)c(Oc2ccc(S(C)(=O)=O)nc2)cc2cc(C3=NCC(CCO)S3)[nH]c12,,C1CCOC1,,CO,[BH4-].[Li+],test
US20120017994A1,CC(C)(C)CC(C)(C)c1ccc(Nc2ccc(C(C)(C)CC(C)(C)C)cc2)cc1.O=[N+]([O-])c1ccc(F)cc1>>CC(C)(C)CC(C)(C)c1ccc(N(c2ccc([N+](=O)[O-])cc2)c2ccc(C(C)(C)CC(C)(C)C)cc2)cc1,,CO,,CS(C)=O,[H-].[Na+],test
US20160194316A1,COC(Cc1cc(C)c(C#N)c(=O)n1N)OC.Cl>>Cc1cc2cc[nH]n2c(=O)c1C#N.Cl,,C1CCOC1,,,,test
US20080051404A1,CC(C)(C)[Si](C)(C)OC[C@@H]1C[C@@H](Oc2ccnc(Cl)c2)C[C@@H]1O[Si](C)(C)C(C)(C)C.CC1(C)C[C@H](N)c2ccc(Cl)cc21>>CC1(C)C[C@H](Nc2cc(O[C@H]3C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](CO[Si](C)(C)C(C)(C)C)C3)ccn2)c2ccc(Cl)cc21,,COCCOC,,CCOC(C)=O,CC(C)(C)[O-].[K+],test
US20070105908A1,NC(N)=S.O=CC(Br)CCN1C(=O)c2ccccc2C1=O>>Nc1ncc(CCN2C(=O)c3ccccc3C2=O)s1,,CC(=O)O,,,,test
US20160200728A1,CC(=O)c1ccc(-c2ccc3c(n2)Oc2c(F)cccc2[C@@H]3C(C)(C)c2nc3nccnc3[nH]2)cc1.C[Mg]Br>>CC(C)(O)c1ccc(-c2ccc3c(n2)Oc2c(F)cccc2[C@@H]3C(C)(C)c2nc3nccnc3[nH]2)cc1,,C1CCOC1,,,,test
US04599357,CC(CSC(=O)c1ccccc1)C(=O)Cl.O=C(O)C1Cc2ccccc2N1>>CC(CSC(=O)c1ccccc1)C(=O)N1c2ccccc2CC1C(=O)O,,CCN(CC)CC,,Cl,ClCCl,test
US20140323463A1,CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3nc(Oc4cccc([N+](=O)[O-])c4)cnc3C(N)=O)cc2Br)CC1>>NC(=O)c1ncc(Oc2cccc([N+](=O)[O-])c2)nc1Nc1ccc(N2CCNCC2)c(Br)c1,,ClCCCl,,O=C(O)C(F)(F)F,,test
US20110015240A1,CC(=O)Nc1nc(CCc2ccc(COC(=O)NNC(=O)OC(C)(C)C)c(F)c2)cs1.Cl>>CC(=O)Nc1nc(CCc2ccc(COC(=O)NN)c(F)c2)cs1.Cl,,ClCCl,,C1COCCO1,,test
US05296492,CCOC(=O)c1ccn([C@@H]2c3cc(C#N)ccc3OC(C)(C)[C@H]2O)c(=O)c1.CS(=O)(=O)Cl.ClCCl>>CCOC(=O)c1ccn([C@@H]2c3cc(C#N)ccc3OC(C)(C)[C@H]2COS(C)(=O)=O)c(=O)c1,,ClCCl,,CCN(CC)CC,O,test
US20070244153A1,CC(C)[C@H](N)CNC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C.Cc1ccc(C(=O)O)cc1>>Cc1ccc(C(=O)N[C@H](CNC(=O)[C@@H](NC(=O)OCc2ccccc2)C(C)C)C(C)C)cc1,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US05098613,CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)C(=O)O.NO>>CCc1cc(CC=NO)c(O)cc1OCCCCCC(C)(C)C(=O)O,,CO,,Cl,CC(=O)[O-].[Na+],test
US20070281933A1,Cc1nc(S(=O)(=O)Cl)cn1C.NC(=O)c1cc(-c2ccc(CO)cc2)cc2c(C3CCNCC3)n[nH]c12>>Cc1nc(S(=O)(=O)N2CCC(c3n[nH]c4c(C(N)=O)cc(-c5ccc(CO)cc5)cc34)CC2)cn1C,CN(C)c1ccncc1,,,CCN(C(C)C)C(C)C,,test
US20100267773A1,COc1ccc(C(=O)Cl)cc1F.COc1ccc(Nc2ccc(F)cc2)cc1>>COc1ccc(N(C(=O)c2ccc(OC)c(F)c2)c2ccc(F)cc2)cc1,,C1CCOC1,,c1ccncc1,,test
US20100197679A1,CCOC(=O)C=O.COc1ccc(N)c(Nc2nc3c(s2)CC(NC(=O)OC(C)(C)C)CC3)n1>>CCOC(=O)/C=N/c1ccc(OC)nc1Nc1nc2c(s1)CC(NC(=O)OC(C)(C)C)CC2,,Cc1ccccc1,,,,test
US20030045727A1,O=C(CCCN1CCN(c2ncc(F)cn2)CC1)c1ccc(F)cc1>>OCCCCN1CCNCC1,,CC(C)O,,CC(C)(C)O,CC(C)(C)[O-].[K+],test
US04026936,N.O=[N+]([O-])c1cc(Cc2ccccn2)ccc1Cl>>Nc1ccc(Cc2ccccn2)cc1[N+](=O)[O-],,CCO,,,,test
US20120258925A1,C=C[C@@H](OCc1ccccc1)[C@H](F)CN=[N+]=[N-].O.O=C(O)C(F)(F)F>>[N-]=[N+]=NC[C@@H](F)[C@H](OCc1ccccc1)C(=O)O,,C1COCCO1,CCOC(C)=O,,,test
US20030207899A1,O=C(Nc1ccon1)OCC(Cl)(Cl)Cl.O=C1O[C@@H](CO)CN1c1ccc(N2CCOCC2)c(F)c1>>O=C1O[C@@H](CNc2ccon2)CN1c1ccc(N2CCOCC2)c(F)c1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US06177440B1,COC(=O)CBr.NC(=O)c1cccc2[nH]c3c(Cl)ccc(O)c3c12>>COC(=O)COc1ccc(Cl)c2[nH]c3cccc(C(N)=O)c3c12,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US04200641,C=C(C)n1c(=O)n(CCCCl)c2ccccc21.c1ccc(CN2CCNCC2)cc1>>C=C(C)n1c(=O)n(CCCN2CCN(Cc3ccccc3)CC2)c2ccccc21,,CC(=O)CC(C)C,O,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US05554757,CC1(C)COC(c2ccccc2-c2ccc(COC3CCCCO3)cc2)=N1>>CC1(C)COC(c2ccccc2-c2ccc(CO)cc2)=N1,,CO,,Cl,O=C([O-])O.[Na+],test
US20050009889A1,Cc1cc(Cl)c(C(=O)Cl)c(Cl)n1.NCc1ncc(C(F)(F)F)cc1Cl>>Cc1cc(Cl)c(C(=O)NCc2ncc(C(F)(F)F)cc2Cl)c(Cl)n1,,ClCCl,,CCN(CC)CC,Cl,test
US20150191458A1,CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(NC(=O)c3ncn(-c4ccc(OC(F)F)cc4)n3)cc2)C1.Cl>>Cl.O=C(Nc1ccc([C@H]2CNCCO2)cc1)c1ncn(-c2ccc(OC(F)F)cc2)n1,,C1COCCO1,,CCOCC,,test
US20160137649A1,CCI.CCOC(=O)c1[nH]ncc1CN1CC2CN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC2C1>>CCOC(=O)c1c(CN2CC3CN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC3C2)cnn1CC,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05792764,CC(N)CO.CSC1=NS(=O)(=O)c2cnccc2N1>>CC(CO)NC1=NS(=O)(=O)c2cnccc2N1,,CCOCC,,O,,test
US20090111800A1,NC1CCc2n[nH]cc2C1.O=CC[C@@H](Cc1c(Cl)cc(C(F)(F)F)c(F)c1F)C(=O)N1C(=O)OC[C@H]1Cc1ccccc1>>O=C1[C@H](Cc2c(Cl)cc(C(F)(F)F)c(F)c2F)CCN1C1CCc2n[nH]cc2C1,,CO,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160002242A1,O=[N+]([O-])c1cnn(CCn2cccn2)c1>>Nc1cnn(CCn2cccn2)c1,[Pd],CO,,,,test
US20140350019A1,CC(C)OC(=O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1F.N>>NC(=O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1F,,C1COCCO1,,,,test
US20030195201A1,Nc1ccc2c(c1)OCCO2.Nc1ccnc(Cl)c1>>Nc1ccnc(Nc2ccc3c(c2)OCCO3)c1,[Cu]I,,,,,test
US05442064,COC(=O)CC1CCN(C(=O)Oc2ccc([N+](=O)[O-])cc2)CC1.N#Cc1ccc(C2CCNCC2)cc1>>COC(=O)CC1CCN(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)CC1,,CCOC(C)=O,,,,test
US20030195176A1,CC(C)(C)[Si](C)(C)O[C@H]1C[C@H](O[Si](C)(C)C(C)(C)C)CC2=CC=C3[C@@H]4CC=C(CO)[C@@]4(C)CC[C@@H]3[C@]21C.CC[Si](CC)(CC)OC(C)(C)C#CCBr>>CC[Si](CC)(CC)OC(C)(C)C#CCOCC1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,C1COCCOCCOCCOCCO1,[H-].[Na+],test
US20160237043A1,CC(C)(C)O.C[C@@]1(C(=O)O)CC1c1ccc(F)cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N[C@]1(C)CC1c1ccc(F)cc1,,CCOC(C)=O,Cc1ccccc1,CCN(CC)CC,,test
US20100063013A1,C#CCO[Si](C)(C)C(C)(C)C.CC(C)C[C@H]1COC(c2cc3ccccc3s2)(C(F)(F)F)N1>>CC(C)C[C@@H](CO)N[C@@](C#CCO[Si](C)(C)C(C)(C)C)(c1cc2ccccc2s1)C(F)(F)F,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20100121048A1,Br[Mg]C1CC1.CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)C[C@H]1C=O>>CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)C[C@H]1C(O)C1CC1,,C1CCOC1,,[Cl-].[NH4+],,test
US20100048632A1,CC(C)c1noc(N2CCC(CCCO)CC2)n1.CS(=O)(=O)c1ccc(O)cc1F>>CC(C)c1noc(N2CCC(CCCOc3ccc(S(C)(=O)=O)c(F)c3)CC2)n1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070219181A1,C[C@H](C(=O)NNC(=O)OC(C)(C)C)c1ccccc1.Cl>>C[C@H](C(=O)NN)c1ccccc1.Cl,,CCOC(C)=O,,CCOCC,,test
US20100144884A1,COCCOCCl.COc1cc(O)ccc1C=O>>COCCOCOc1ccc(C=O)c(OC)c1,,C1CCOC1,CN(C)C=O,O,[H-].[Na+],test
US05346647,CCCCCCCOc1ccc(C(=O)O)c(F)c1F.CCCCC[C@@H]1CC[C@@H](CCCCc2ccc(O)cc2)CC1>>CCCCCCCOc1ccc(C(=O)Oc2ccc(CCCC[C@@H]3CC[C@@H](CCCCC)CC3)cc2)c(F)c1F,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20050277630A1,COc1ccc(CNc2n[nH]c3c2CCOc2cc(N4C[C@H](CNC(C)=O)OC4=O)ccc2-3)cc1>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)OCCc2c(N)n[nH]c2-3)C(=O)O1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20030114458A1,COc1c(F)nc(F)c(F)c1OC(C)(C)C.NN>>COc1c(F)nc(NN)c(F)c1OC(C)(C)C,,CCCO,,O,,test
US20100063038A1,C1COCCN1.Nc1ncnn2c(CCBr)cc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)c(F)c3)c12>>Nc1ncnn2c(CCN3CCOCC3)cc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)c(F)c3)c12,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,[I-].[Na+],test
US20040132727A1,CC(C)N(CCN)C(C)C.COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2ncnc(Oc3ccc(NC(=O)NCCN(C(C)C)C(C)C)cc3)c2cc1OC,,ClC(Cl)Cl,O,CCN(CC)CC,,test
US20080319188A1,Nc1ccc(Oc2ccnc(N(C(=O)Oc3ccccc3)C(=O)Oc3ccccc3)c2)cc1F.O=C(O)C1(C(=O)Nc2ccccc2F)CC1>>O=C(Oc1ccccc1)N(C(=O)Oc1ccccc1)c1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccccc4F)CC3)c(F)c2)ccn1,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20050245764A1,COC(=O)[C@@H](O)Cc1ccccc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>COC(=O)[C@H](Cc1ccccc1)OS(=O)(=O)c1ccc(Cl)cc1,,O,,CCN(CC)CC,Cc1ccccc1,test
US20020120148A1,NCc1ccccc1.O=C1CCCc2ccc([N+](=O)[O-])cc2C1>>O=[N+]([O-])c1ccc2c(c1)CC(NCc1ccccc1)CCC2,,CC(=O)O,ClCCCl,[Na+].[OH-],,test
US20160194350A1,CC[C@H](OC(=O)c1ccccc1)[C@@H]1C[C@@H](C)[C@H](n2c(=O)sc3c(=O)[nH]c(N)nc32)O1>>CC[C@H](O)[C@@H]1C[C@@H](C)[C@H](n2c(=O)sc3c(=O)[nH]c(N)nc32)O1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20120225858A1,C[C@@](NC(=O)C(F)(F)F)(c1ccccc1F)[C@H]1COC[C@@H]1SCC#N>>C[C@@](N)(c1ccccc1F)[C@H]1COC[C@@H]1SCC#N,,CCO,,[BH4-].[Na+],,test
US06451501B1,C=C(C)C(=O)Cl.O=C1CC(O)C(=O)O1>>C=C(C)C(=O)OC1CC(=O)OC1=O,,ClCCl,,CCN(CC)CC,,test
US06156700,CSCc1nsc2ccc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)cc12.O=C(OO)c1cccc(Cl)c1>>Cn1c(C(F)(F)F)cc(=O)n(-c2ccc3snc(CS(C)=O)c3c2)c1=O,,ClCCl,,CCOC(C)=O,,test
US20090036450A1,CC(=O)CC(=O)OCCCl.NC=O>>CCOC(=O)c1ocnc1C,,O,,,,test
US20100216788A1,FC(F)(F)Oc1cccc(CBr)c1.O=[N+]([O-])c1ccc2[nH]ccc2c1>>O=[N+]([O-])c1ccc2c(ccn2Cc2cccc(OC(F)(F)F)c2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05753661,CS(=O)(=O)Cl.O=S(=O)(CCCO)C1CCCCC1>>CS(=O)(=O)OCCCS(=O)(=O)C1CCCCC1,,ClCCl,,CCN(CC)CC,,test
US20040157804A1,CCOC(=O)Oc1c2c(c(OC(c3ccccc3)c3ccccc3)c3ncccc13)C(=O)N(Cc1ccc(OC)cc1OC)C2=O.CI>>COc1ccc(CN2C(=O)c3c(c(OC(c4ccccc4)c4ccccc4)c4ncccc4c3OC)C2=O)c(OC)c1,,C1CCOC1,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US06162808,CN.Cc1ccc2c(c1)C=Cc1cc(C)ccc1C2c1cn(Cc2nc(C(=O)O)co2)c(=O)[nH]c1=S>>CNC(=O)c1coc(Cn2cc(C3c4ccc(C)cc4C=Cc4cc(C)ccc43)c(=S)[nH]c2=O)n1,,C1CCOC1,CN(C)C=O,,,test
US20100331293A1,CCCC[Sn](CCCC)(CCCC)c1cc(Cl)ccn1.Cc1c(Cl)nc2cc(F)cc(F)c2c1Cl>>Cc1c(-c2cc(Cl)ccn2)nc2cc(F)cc(F)c2c1Cl,,Cc1ccccc1,,,,test
US20110091952A1,CCCCCCCCCC(C[C@@H]1CC(=O)O1)OC.O>>CCCCCCCCCC(C[C@@H](O)CC(=O)O)OC,,C1CCOC1,O,[Na+].[OH-],,test
US20110288063A1,Cn1nc(CO)c2c1C1(C)CCC2C1(C)C>>Cn1nc(C=O)c2c1C1(C)CCC2C1(C)C,,CC#N,,,,test
US20160207883A1,COC(=O)c1ccc(C#N)cc1Oc1ccc(COC2CCOCC2)cc1>>N#Cc1ccc(CO)c(Oc2ccc(COC3CCOCC3)cc2)c1,,C1CCOC1,,O,[BH4-].[Li+],test
US04310590,C1CCNCC1.O=c1cc(Cl)sn1CCc1ccccc1>>O=c1cc(N2CCCCC2)sn1CCc1ccccc1,,ClC(Cl)Cl,,CCN(CC)CC,[I-].[Na+],test
US20060079533A1,BrCc1ccc2ccccc2c1.CN1C2CCC1C(O)C(c1ccc(Cl)cc1)C2>>CN1C2CCC1C(OCc1ccc3ccccc3c1)C(c1ccc(Cl)cc1)C2,,C1CCOC1,,[H-].[Na+],,test
US04873251,CC(C(=O)O)n1c(-c2ccc(Cl)cc2)nc2cccnc21.OCCO>>C[C@@H](C(=O)OCCO)n1c(-c2ccc(Cl)cc2)nc2cccnc21,O=S(=O)(O)O,,,O,O=C([O-])O.[Na+],test
US20040092546A1,NCc1ccccc1.O=C(c1cc(S(=O)(=O)Cl)c[nH]1)c1cccnc1Cl>>O=C(c1cc(S(=O)(=O)NCc2ccccc2)c[nH]1)c1cccnc1Cl,,ClCCl,,CCN(CC)CC,,test
US20070155805A1,CCCCC(CCOc1ccc(CCC(=O)OCC)cc1)c1sc2cc(C(F)(F)F)ccc2c1C>>CCCCC(CCOc1ccc(CCC(=O)O)cc1)c1sc2cc(C(F)(F)F)ccc2c1C,,C1CCOC1,CO,[Na+].[OH-],,test
US20120309739A1,COc1nc(S(C)(=O)=O)nc2oc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)c12>>COc1ncnc2oc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)c12,,CCO,ClCCl,Cl,[BH4-].[Na+],test
US06632826B1,C=C(CBr)CS(=O)(=O)c1ccccc1.COC(=O)C=CCC1OC(C)(C)N(C(=O)OC(C)(C)C)C1Cc1ccccc1>>C=C1CC(C(=O)OC)C(CC2OC(C)(C)N(C(=O)OC(C)(C)C)C2Cc2ccccc2)C1S(=O)(=O)c1ccccc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US09227971B2,COc1ccc(-c2ccc(-c3cnn4c(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)c(Br)c(C5CC6CCC(C5)N6C(=O)OC(C)(C)C)nc34)cn2)cc1CO.O>>COc1ccc(-c2ccc(-c3cnn4c(N)c(Br)c(C5CC6CCC(C5)N6C(=O)CO)nc34)cn2)cc1CO,,O,,C1COCCO1,Cl,test
US20140275011A1,BrCC1CCOCC1.Brc1ccc2c(c1)NCC2>>Brc1ccc2c(c1)N(CC1CCOCC1)CC2,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050187236A1,Nc1cc(Cl)ccn1.Oc1ccc2cc[nH]c2c1>>Nc1cc(Oc2ccc3cc[nH]c3c2)ccn1,,CS(C)=O,,[H-].[Na+],,test
US20080096882A1,CCOC(=O)c1ccc(N2CCNCC2)cc1.O=S1CCc2nc(Cl)nc(Nc3cccc(Cl)c3)c21>>CCOC(=O)c1ccc(N2CCN(c3nc4c(c(Nc5cccc(Cl)c5)n3)S(=O)CC4)CC2)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,O,test
US06407129B1,CC(=O)OCBr.C[C@@H](N1CCN(c2ccc(-n3ccnn3)cc2)C1=O)[C@](O)(Cn1cncn1)c1ccc(F)cc1F>>CC(=O)OCN1C=N[NH+](C[C@](O)(c2ccc(F)cc2F)[C@@H](C)N2CCN(c3ccc(-n4ccnn4)cc3)C2=O)C1.[Br-],,CC#N,,,,test
US20130184284A1,CC(C)(C)OC(=O)N[C@@H]1CCCC[C@H]1NC1CCCNC1.FC(F)(F)c1ncc(Br)cn1>>CC(C)(C)OC(=O)N[C@@H]1CCCC[C@H]1NC1CCCN(c2cnc(C(F)(F)F)nc2)C1,,CC(=O)N(C)C,,,,test
US20060281700A1,CC(C)Oc1ccc(NC(=O)Oc2ccc([N+](=O)[O-])cc2)cc1.CON=Cc1c(N)ncnc1N1CCC(N)CC1>>CON=Cc1c(N)ncnc1N1CCC(NC(=O)Nc2ccc(OC(C)C)cc2)CC1,,CC#N,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20140155597A1,COC(=O)c1ccc2c(c1)CNC2=O>>O=C(O)c1ccc2c(c1)CNC2=O,,CO,,Cl,[Na+].[OH-],test
US06555634B1,CC(C)(C)N[Si](C)(C)Cl.[Li]C1C=C(c2ccccc2)c2cc(OC)c(OC)cc21>>COc1cc2c(cc1OC)C([Si](C)(C)NC(C)(C)C)C=C2c1ccccc1,,C1CCOC1,,,,test
US06028096,CCC(=O)OC.N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)cc1I>>CCC(=O)c1cn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)nc1C#N,,C1CCOC1,,O,[Li]CCCC,test
US04110454,CCOC(=O)c1cnc2c(cnn2CC)c1NN.CCOC=NC#N>>CCn1ncc2c1ncc1c(=O)[nH]c3ncnn3c12,,C1COCCO1,,,,test
US20150152047A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1cc(Br)c(C)cc1N>>CCOC(=O)c1cc(Br)c(C)cc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,CN(C)c1ccncc1,C1CCOC1,,,,test
US20150087646A1,CC(C)(C)OC(=O)NNc1ccc(C(F)(F)F)nc1.O=C=NC(=O)c1cc(CNC(=O)C(F)(F)F)ccc1Cl>>O=C(NCc1ccc(Cl)c(-c2nn(-c3ccc(C(F)(F)F)nc3)c(=O)[nH]2)c1)C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US05354747,CCOC(=O)C(Br)CBr.c1ccc(CNCCNc2ccccc2)cc1>>CCOC(=O)C1CN(Cc2ccccc2)CCN1c1ccccc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20090099205A1,C/C=C/C#N.C1CC2(CCN1)OCCO2>>CC(CC#N)N1CCC2(CC1)OCCO2,,CO,,,,test
US20130158075A1,Nc1ccc(-c2cnc(CCNS(=O)(=O)C(F)(F)F)s2)cc1.O=C(Cl)c1ccccc1Cl>>O=C(Nc1ccc(-c2cnc(CCNS(=O)(=O)C(F)(F)F)s2)cc1)c1ccccc1Cl,,ClCCl,,CCN(CC)CC,,test
US20140094474A1,C[C@@H](Cn1ccc(-c2cc(F)c(C#N)c(Cl)c2)n1)NC(=O)c1cc(CBr)on1.c1c[nH]cn1>>C[C@@H](Cn1ccc(-c2cc(F)c(C#N)c(Cl)c2)n1)NC(=O)c1cc(Cn2ccnc2)on1,,CCOC(C)=O,CN(C)C=O,,,test
US20070093490A1,C1CCOC1.COc1cc(-c2cnc3ccc(NC4CCN(C(=O)OC(C)(C)C)CC4)nn23)ccn1>>c1ccc(-c2cnc3ccc(NCCCN4CCCC4)nn23)cc1,,C1COCCO1,O,CCN(CC)CC,Cl,test
US20050233988A1,CC(=O)OC[C@H]1O[C@@H](c2ccc(C)c(Cc3ccc(-c4ccc(F)nc4)s3)c2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>Cc1ccc([C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1Cc1ccc(-c2ccc(F)nc2)s1,,C1CCOC1,C1COCCO1,O=C(O)CC(O)(CC(=O)O)C(=O)O,[Na+].[OH-],test
US20120329649A1,C[Si](C)(C)C(F)(F)F.O=C(/C=C/c1ccc(-n2cncn2)cc1)c1cc(Cl)cc(Cl)c1>>OC(/C=C/c1ccc(-n2cncn2)cc1)(c1cc(Cl)cc(Cl)c1)C(F)(F)F,,C1CCOC1,,Cl,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100204285A1,Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CN)c1.O=C(Cl)c1cccc2sc(Cl)nc12>>Cc1cccc(-c2sc(C)nc2C(=O)N2C[C@@H]3C[C@@H]3[C@H]2CNC(=O)c2cccc3sc(Cl)nc23)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20050239769A1,CCCc1c(CCCCO)ccc2c(C(F)(F)F)noc12.CS(=O)(=O)Cl>>CCCc1c(CCCCOS(C)(=O)=O)ccc2c(C(F)(F)F)noc12,,ClCCl,,CCN(CC)CC,Cl,test
US04093805,Nc1ccc(Cl)cc1C(=O)c1ccccc1.S=C(Cl)Cl>>O=C(c1ccccc1)c1cc(Cl)ccc1N=C=S,,ClCCl,,O,,test
US20040127576A1,CC(C)=O.O=Cc1ccc(OCc2ccccc2)cc1I>>CC(=O)C=Cc1ccc(OCc2ccccc2)cc1I,,O,,[Na+].[OH-],,test
US04174959,CC(=O)c1ccccc1.Cc1nc2cc(C(F)(F)F)cc(N)c2n1C(C)C>>CC(=Nc1cc(C(F)(F)F)cc2nc(C)n(C(C)C)c12)c1ccccc1,,Cc1ccccc1C,,,,test
US20120070410A1,CC(C)(CO)c1cc(N)no1.O=C(Cl)Oc1ccccc1>>CC(C)(CO)c1cc(NC(=O)Oc2ccccc2)no1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20050187390A1,CC(=O)c1ccc(-n2ccnc2)cc1.O=C(O)c1ccc2c(c1)nc(-c1ccc3nc(-c4cc(Br)ccc4O)ccc3c1)n2C1CCCCC1>>O=C(O)c1ccc2c(c1)nc(-c1ccc3nc(-c4ccc(-n5ccnc5)cc4)ccc3c1)n2C1CCCCC1,,CCO,,[K+].[OH-],,test
US20140142085A1,CCOC(=O)CBr.FC(F)(F)c1n[nH]c2c1CC1(CC2)OCCO1>>CCOC(=O)Cn1nc(C(F)(F)F)c2c1CCC1(C2)OCCO1,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20020094994A1,CCOC(=O)C1CN(C(=O)c2ccccc2)CC1c1ccc(NC(=O)Cc2ccc(NC(=O)Nc3ccccc3C)c(OC)c2)cc1>>COc1cc(CC(=O)Nc2ccc(C3CN(C(=O)c4ccccc4)CC3C(=O)O)cc2)ccc1NC(=O)Nc1ccccc1C,,CCO,,[Na+].[OH-],,test
US20090264445A1,CC#CC(=O)OCC.COc1ccc(F)c(O)c1F>>CCOC(=O)/C=C(\C)Oc1c(F)ccc(OC)c1F,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20160075653A1,ON=C1CCC1c1c(F)cccc1F>>NC1CCC1c1c(F)cccc1F,O=[Pt]=O,CCO,ClC(Cl)Cl,[H][H],,test
US20120316165A1,CC(C)(C)OC(=O)N1CCOC(c2ccc(N)c(C#N)c2)C1.N#Cc1cccc(N)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)N1CCOC(c2ccc(NC(=O)Nc3cccc(C#N)c3)c(C#N)c2)C1,,ClCCl,O,O=C([O-])[O-].[Na+].[Na+],,test
US04680300,ClCCCCCCCCOc1ccc2ccccc2c1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1CCCCCCCCOc1ccc2ccccc2c1,,CN(C)C=O,,O,[K],test
US20050176701A1,CN=C=S.NNC(=O)CCN1CCOCC1>>Cn1c(S)nnc1CCN1CCOCC1,,CCO,,,,test
US20030212111A1,CCNc1ccc(C(C)=O)cc1N=C1SC(=C2Sc3ccccc3N2C)C(=O)N1Cc1ccccc1>>CCNc1ccc(C(C)O)cc1N=C1SC(=C2Sc3ccccc3N2C)C(=O)N1Cc1ccccc1,,C1CCOC1,CO,[BH4-].[Na+],,test
US20050256159A1,Clc1ncccn1.O=C(c1ccc(F)cc1)C1CCNCC1>>O=C(c1ccc(F)cc1)C1CCN(c2ncccn2)CC1,,CCO,,CCN(CC)CC,Cl,test
US20080015199A1,CC(C)(C)[Si](C)(C)OCCBr.COC(=O)N=C(SC)C(=Nc1ccc(-c2noc(C)n2)cc1)c1cc(OC)cc(O)c1F>>COC(=O)N=C(SC)C(=Nc1ccc(-c2noc(C)n2)cc1)c1cc(OC)cc(OCCO[Si](C)(C)C(C)(C)C)c1F,,CN(C)C=O,O,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20100105604A1,C=C(C)CBr.CCOC(=O)c1cccc(O)c1>>C=C(C)COc1cccc(C(=O)O)c1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050130941A1,CC(C)(C)N=C=O.NC(=O)C[C@H](NC(=O)c1ccc2ccccc2n1)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(N)CC1CCCCC1>>CC(C)(C)NC(=O)NN(CC1CCCCC1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1,,C1CCOC1,,,,test
US20120095002A1,CS(=O)(=O)Cl.O=C(NC1CCCC1)c1onc(-c2ccc(C(F)(F)F)c(F)c2)c1CO>>O=C(NC1CCCC1)c1onc(-c2ccc(C(F)(F)F)c(F)c2)c1CCl,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,O,test
US20100267666A1,COc1cc(-c2cnc3[nH]cc(C(=O)C4(C)COC(C)(C)OC4)c3n2)cc(OC)c1OC>>COc1cc(-c2cnc3[nH]cc(C(=O)C(C)(CO)CO)c3n2)cc(OC)c1OC,,C1CCOC1,CO,Cl,,test
US20110201605A1,CCOC(=O)CCN(Cc1ccccc1)CC(F)(F)C(=O)OCC>>CCOC(=O)C1CN(Cc2ccccc2)CC(F)(F)C1=O,,CN1CCCC1=O,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US20150232481A1,C=CCOC1(C)CCN(C(=O)OC(C)(C)C)CC1.OO>>CC(C)(C)OC(=O)N1CCC(C)(OCCCO)CC1,,C1CCOC1,,B1C2CCCC1CCC2,[Na+].[OH-],test
US20120322785A1,Cc1cc(C=O)ncc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1>>Cc1cc(CO)ncc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1,,C1CCOC1,,[Na],,test
US04582644,COC1=CC2=CC[C@H]3[C@@H]4CCC(=O)[C@@]4(C)CC[C@@H]3[C@@]2(C)CC1.NCCN>>C#C[C@@]1(O)CC[C@H]2[C@@H]3CC=C4C=C(OC)CC[C@]4(C)[C@H]3CC[C@@]21C,,CC(C)(C)O,,[K+].[OH-],,test
US20040087568A1,CC(C)(C)OC(=O)N1Cc2cc(N)ccc2C(C)(C)C1.O=C(O)c1ccccc1NCc1c[nH]c2ncccc12>>CC(C)(C)OC(=O)N1Cc2cc(NC(=O)c3ccccc3NCc3c[nH]c4ncccc34)ccc2C(C)(C)C1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20080255153A1,CCOC(=O)c1c[nH]nc1N.COC(=O)C(Cc1ccc(Cl)c(Cl)c1)C(=O)OC>>O=C(O)c1cnn2cc(Cc3ccc(Cl)c(Cl)c3)cnc12,,CO,ClCCl,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US05294618,ClCc1ccc(Cl)cc1.c1ccc2c(c1)CC[C@@H]1CNCC[C@@H]21>>Clc1ccc(CN2CC[C@H]3c4ccccc4CC[C@@H]3C2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070021606A1,CC(C)(C)OC(=O)COCc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl>>O=C(O)COCc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl,,O=CO,,,,test
US20030060460A1,CO.Nc1cc(C(F)(F)F)ccc1NS(=O)(=O)c1ccccc1.O=Cc1ccc(C=O)cc1>>COC(=O)c1ccc(CNc2cc(C(F)(F)F)ccc2NS(=O)(=O)c2ccccc2)cc1,,CC(=O)O,,[BH3-]C#N.[Na+],,test
US04315766,Nc1cccc(-c2nc3ccccc3c(=O)o2)c1.O=C(Cl)Cl>>O=C=Nc1cccc(-c2nc3ccccc3c(=O)o2)c1,,Clc1ccccc1,,Cl,,test
US20080058383A1,Cc1cccc(F)c1C.O=[N+]([O-])O>>Cc1c(F)ccc([N+](=O)[O-])c1C,,CC(=O)OC(C)=O,,,,test
US20080261969A1,CCOC(=O)c1[nH]ccc1N.O=C1CCCC(=O)C1.O=Cc1ccc(Sc2nc3ccc(F)c(F)c3[nH]2)o1>>CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CCC1)C2c1ccc(Sc2nc3ccc(F)c(F)c3[nH]2)o1,,CCCCO,,,,test
US20140296246A1,CCOc1nc2c(C(O)(c3ccccn3)c3cccc(Cl)n3)cc(-c3c(C)noc3C)cc2n1C(=O)OC(C)(C)C.COCCO>>COCCOc1cccc(C(O)(c2ccccn2)c2cc(-c3c(C)noc3C)cc3[nH]c(=O)[nH]c23)n1,,C1CCOC1,,[H-].[Na+],,test
US20130059834A1,CCc1cc(Br)cc2cn[nH]c12>>CCc1cccc2cn[nH]c12,[Pd],CCO,,,,test
US04883815,CC(=O)NCCCC(=O)c1ccc(Cl)cc1CCC(=O)O.OCc1cccnc1>>CC(=O)NCCCC(=O)c1ccc(Cl)cc1CCC(=O)OCc1cccnc1,,ClCCl,,O=S(Cl)Cl,,test
US20100317706A1,CCI.Cc1ccccc1NS(=O)(=O)c1cc([N+](=O)[O-])ccc1C>>CCN(c1ccccc1C)S(=O)(=O)c1cc([N+](=O)[O-])ccc1C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100311760A1,COc1nc(F)ccc1F.OCc1ccccc1>>COc1nc(OCc2ccccc2)ccc1F,,C1CCOC1,O,[H-].[Na+],,test
US06323235B1,BrCCOC1CCCCO1.COc1cccc2[nH]ccc12>>COc1cccc2c1ccn2CCO,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20130109662A1,C=C1CC(=O)O1.CNCC(O)CO>>CC(=O)CC(=O)NCC(O)CO,,C1CCOC1,,,,test
US20080269208A1,O=C1NCCN2CCS(=O)(=O)CC12>>O=S1(=O)CCN2CCNCC2C1,,C1CCOC1,,Cl,,test
US20150111734A1,CCN(C(=O)C(C)CC=O)c1cn(-c2cccnc2)nc1Cl.C[Mg]Br>>CCN(C(=O)C(C)CC(C)=O)c1cn(-c2cccnc2)nc1Cl,,C1CCOC1,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US04788185,CCC(Br)C(=O)OC(C)(C)C.CSCCOC(=O)/C(=N\O)c1csc(N)n1>>CCC(O/N=C(\C(=O)OCCSC)c1csc(N)n1)C(=O)OC(C)(C)C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150073138A1,CC#N.CC(=O)c1ccncc1.COS(=O)(=O)OC>>CC(=O)c1cc[n+](C)cc1.COS(=O)(=O)[O-],,CC#N,,CCOC(C)=O,,test
US20110039843A1,FC(F)(F)c1ccc2oc(-c3ccncc3Br)nc2c1.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1ccc(-c2nc3cc(C(F)(F)F)ccc3o2)c(Br)c1,,CCOC(C)=O,,ClC(Cl)Cl,,test
US20120071514A1,CI.Cn1c(=O)oc2ccc(-c3cncc(NS(=O)(=O)C4CC4)c3)cc21>>CN(c1cncc(-c2ccc3oc(=O)n(C)c3c2)c1)S(=O)(=O)C1CC1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US03941782,CCOC(=O)C(C)CCN1CCOCC1.Cl>>CC(CCN1CCOCC1)C(=O)O.Cl,,O,,,,test
US20020018955A1,O=C(O)c1cccc(S(=O)(=O)C(Br)(Br)Br)c1.O=S(Cl)Cl>>O=C(Cl)c1cccc(S(=O)(=O)C(Br)(Br)Br)c1,,CN(C)C=O,,,,test
US20060217393A1,CI.CN1CCN(c2cc(I)c(NC(=O)C(C)(C)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cn2)CC1>>CN1CCN(c2cc(I)c(N(C)C(=O)C(C)(C)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cn2)CC1,,C1CCOC1,CN(C)C=O,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20150183810A1,CC1CN1P(=O)(Oc1ccccc1)Oc1ccccc1.Cl[Mg]c1ccccc1>>CC(Cc1ccccc1)NP(=O)(Oc1ccccc1)Oc1ccccc1,Cl[Cu],C1CCOC1,,,,test
US03991196,COc1cc2oc(=O)c3c(c2cc1OC)CCNC3.Cl.ClCC=NCCCCCCCl>>COc1cc2oc(=O)c3c(c2cc1OC)CCN(CCN1CCCCCC1)C3.Cl.Cl,,CCO,,CCN(CC)CC,,test
US20040171623A1,CCCn1c(Cl)cc(=O)n(C)c1=O.[SH-]>>CCCn1c(S)cc(=O)n(C)c1=O,,CCO,,O,,test
US08030309B2,Brc1cc2ccccc2[nH]1.C1CCOC1>>Cc1cc2ccccc2[nH]1,,C1CCOC1,,[Li]CCCC,,test
US04656298,CCOC(OCC)P(=O)(CC(C[N+](=O)[O-])c1ccc(C)cc1)OCC>>CCOC(OCC)P(=O)(CC(CN)c1ccc(C)cc1)OCC,[Ni],CCO,,N,[H][H],test
US20160255837A1,CNc1nc2c(cc1[N+](=O)[O-])nc(C(F)(F)F)n2C>>CNc1nc2c(cc1N)nc(C(F)(F)F)n2C,[Pd],CCOC(C)=O,CO,[H][H],,test
US20100016258A1,CCCCCCCCCCCCCCCC(=O)Cl.COC(=O)[C@@H](N)Cc1ccc(O)cc1>>CCCCCCCCCCCCCCCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O,,ClCCl,,CCN(CC)CC,Cl,test
US20090143366A1,Nc1nccc(-c2ccc(F)c(C(O)c3ccccc3)c2)n1>>Nc1nccc(-c2ccc(F)c(C(=O)c3ccccc3)c2)n1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04370497,COc1ccc([Te](=O)c2ccc(OC)cc2)cc1.Oc1ccc(O)c2ccccc12>>COc1ccc([Te]c2ccc(OC)cc2)cc1.O=C1C=CC(=O)c2ccccc21,,ClC(Cl)Cl,,,,test
US04402960,COc1ccc(-c2nc(Sc3ccccc3NC(C)=O)[nH]c2-c2ccc(OC)cc2)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(-c2nc(S(=O)c3ccccc3NC(C)=O)[nH]c2-c2ccc(OC)cc2)cc1,,ClCCl,,,,test
US20120208817A1,CCOc1cc(C=O)cc([N+](=O)[O-])c1O.Cl.NC(N)=O.O=C(Cc1ccsc1)c1ccncc1>>CCOc1cc(C2NC(=O)NC(c3ccncc3)=C2c2ccsc2)cc([N+](=O)[O-])c1O.Cl,,CCO,,,,test
US20040198982A1,C[C@H]1C[C@@H](C(=O)OC(C)(C)C)N(C(=O)OC(C)(C)C)C1.O=C(O)C(F)(F)F>>C[C@@H]1CN[C@H](C(=O)O)C1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20080280917A1,BrCCOCc1ccccc1.O=c1ccc(Br)c[nH]1>>O=c1ccc(Br)cn1CCOCc1ccccc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20120309796A1,CC(C)(C)OC(=O)COc1cccc2c1CCCCC2NS(=O)(=O)c1cc(F)cc(C(F)(F)F)c1.CI>>CN(C1CCCCc2c(OCC(=O)OC(C)(C)C)cccc21)S(=O)(=O)c1cc(F)cc(C(F)(F)F)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06048979,NC(c1ccccc1)c1ccccc1.OCCCl>>OCCNC(c1ccccc1)c1ccccc1,,O,,[Na+].[OH-],,test
US06063789,C[Si](C)(C)c1cc2c(s1)C(N)=NC(c1ccccc1)C2.Cl>>Cl.NC1=NC(c2ccccc2)Cc2ccsc21,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130123338A1,CCCCCC=O.CN(C)CCCN>>CCCCCCNCCCN(C)C,,CO,,[BH4-].[Na+],,test
US20100179109A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.OCCCCCCl>>CC(C)(C)[Si](C)(C)OCCCCCCl,,CN(C)C=O,,c1c[nH]cn1,,test
US20040235822A1,COc1cc([N+](=O)[O-])ccc1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1cc([N+](=O)[O-])ccc1S,,ClCCl,,CCN(CC)CC,O,test
US20070010573A1,Clc1ccc(C2=CCNCC2)cc1.O=S1(=O)CCCO1>>O=S(=O)(O)CCCN1CC=C(c2ccc(Cl)cc2)CC1,,CC(C)=O,,,,test
US06638945B1,COc1cc2ncc(NC(=O)OC(C)(C)C)c(Cl)c2cc1OC>>COc1cc2ncc(N)c(Cl)c2cc1OC,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20110207785A1,COC(=O)[C@@H](C)N.C[C@H](C(=O)O)c1ccc(Nc2nc(C(F)(F)F)cs2)cc1>>COC(=O)[C@@H](C)NC(=O)[C@@H](C)c1ccc(Nc2nc(C(F)(F)F)cs2)cc1,,ClCCl,,Cl,O=C(n1ccnc1)n1ccnc1,test
US20090163586A1,Nc1ccc(F)cc1S(N)(=O)=O.O=S(=O)(Cl)c1cccc(F)c1F>>NS(=O)(=O)c1cc(F)ccc1NS(=O)(=O)c1cccc(F)c1F,,c1ccncc1,,,,test
US20070072925A1,CNOC.O=C(Cl)c1cccc(Br)c1>>CON(C)C(=O)c1cccc(Br)c1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20090156557A1,Cc1c(C(F)(F)F)cc(Cl)c(Cl)c1[N+](=O)[O-].Cc1cnc(F)c(I)c1>>Cc1cnc(F)c(-c2c(Cl)cc(C(F)(F)F)c(C)c2[N+](=O)[O-])c1,[Cu],CN1CCCC1=O,,CO,O,test
US20150148349A1,CC(C)(C)OC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)N[C@@H]1CCC[C@H](C(F)(F)F)C1.Cl>>Cl.O=C(N[C@@H]1CCC[C@H](C(F)(F)F)C1)[C@@H]1C[C@H]2C[C@H]2N1,,C1COCCO1,,,,test
US20090318412A1,Cc1ccc(F)c(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2CO)c1>>Cc1ccc2c(c1)C(=O)N1CCN(C(=O)OC(C)(C)C)CC1CO2,,CN(C)C=O,,[H-].[Na+],,test
US20090036492A1,BrP(Br)Br.CN(C)C=O.O=C1CCc2c(cc(F)c(F)c2F)C1>>O=CC1=C(Br)CCc2c1cc(F)c(F)c2F,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20040204427A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.COC(=O)[C@@H](C)CO>>COC(=O)[C@@H](C)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,ClCCl,,c1c[nH]cn1,,test
US20060030585A1,C1CCNC1.O=C(Cl)c1ccc2c(=O)c3ccccc3oc2c1>>O=C(c1ccc2c(=O)c3ccccc3oc2c1)N1CCCC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20090069222A1,CC(C)(C)OC(=O)NCCCCNC(=O)[C@@H](N)Cc1c[nH]c2ccccc12.CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)OC(C)(C)C)C(=O)O>>CC(C)(C)OC(=O)NCCCCNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)OC(C)(C)C,,CN(C)C=O,ClCCl,ClCCCl,On1nnc2ccccc21,test
US20100120859A1,COCCCc1cc(O)cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)c1.CS(=O)(=O)OCC1(CC#N)CC1>>COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)cc(OCC2(CC#N)CC2)c1,,CCOCC,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110275655A1,Cc1ccc(N)cc1.NC(=O)c1cnc(Cl)nc1Cl>>Cc1ccc(Nc2nc(Cl)ncc2C(N)=O)cc1,,CN(C)C=O,,CCN(CC)CC,O,test
US05541324,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1(C)Nc2cc(F)ccc2NC1=O>>CC(C)(C)OC(=O)N1CC(=O)Nc2ccccc21,,O,,C1CCOC1,O=C([O-])[O-].[K+].[K+],test
US06110933,CCCCCCCCCCCCC[C@@H](CC(=O)OCC(Cl)(Cl)Cl)OC(=O)[C@H](CCCC(=O)OCc1ccccc1)N=C=O.CNc1ccccn1>>CCCCCCCCCCCCC[C@@H](CC(=O)OCC(Cl)(Cl)Cl)OC(=O)[C@H](CCCC(=O)OCc1ccccc1)NC(=O)N(C)c1ccccn1,,ClCCl,,CCOC(C)=O,,test
US04200641,CC(C)O.O=c1[nH]c2ccccc2n1CCCN1CCN(C(c2ccccc2)c2ccccc2)CC1>>O.O=c1[nH]c2ccccc2n1CCCN1CCN(C(c2ccccc2)c2ccccc2)CC1,,CC(C)O,,C,,test
US20100144760A1,Cc1ccc(S(=O)(=O)N2C[C@@H]3C[C@@H]3C[C@H]2/C=N/c2ccc(C(F)(F)F)cn2)cc1>>Cc1ccc(S(=O)(=O)N2C[C@@H]3C[C@@H]3C[C@H]2CNc2ccc(C(F)(F)F)cn2)cc1,,ClCCCl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100093788A1,CC(C)(O)CCc1cc(-c2ccccc2C(F)(F)F)cc(N)c1N.O=C(O)C1=NOC2(CCCCC2)C1>>CC(C)(O)CCc1cc(-c2ccccc2C(F)(F)F)cc(NC(=O)C2=NOC3(CCCCC3)C2)c1N,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20150126498A1,CSc1cccc(N)c1.O=[N+]([O-])c1cc(F)ccc1S(=O)(=O)Cl>>CSc1cccc(NS(=O)(=O)c2ccc(F)cc2[N+](=O)[O-])c1,,C1COCCO1,,c1ccncc1,,test
US20150158826A1,CC(C)(C)OC(=O)N1CCN(c2cnc3ccc(C(=O)c4cc(NC(=O)C(C)(C)C)ccc4F)cc3n2)CC1>>Nc1ccc(F)c(C(=O)c2ccc3ncc(N4CCNCC4)nc3c2)c1,,CC(=O)O,,Cl,[Na+].[OH-],test
US06166064,CC(=O)Cl.c1c2c(cc3c1CCC3)CCC2>>CC(=O)c1c2c(cc3c1CCC3)CCC2,,c1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US08399449B2,COc1c(C(=O)NC2CCN(CCO)CC2)n(C)c2c1c(=O)n(CC(=O)c1ccccc1)c1ccccc21.Cl>>COc1c(C(=O)NC2CCN(CCO)CC2)n(C)c2c1c(=O)n(CC(=O)c1ccccc1)c1ccccc21.Cl,,CCOC(C)=O,,CCO,,test
US05108486,CCN(CC)c1ccc(N=C=S)cn1.CNN>>CCN(CC)c1ccc(NC(=S)N(C)N)cn1,,CCO,,,,test
US20070299085A1,Cc1cc(CCl)ccc1[N+](=O)[O-].FC(F)(F)c1n[nH]cc1Cl>>Cc1cc(Cn2cc(Cl)c(C(F)(F)F)n2)ccc1[N+](=O)[O-],,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US06015774,CCOC(=O)C(C)Br.Cn1c(C(F)(F)F)cnc(-c2cc(N)c(Cl)cc2Cl)c1=O>>CCOC(=O)C(C)Nc1cc(-c2ncc(C(F)(F)F)n(C)c2=O)c(Cl)cc1Cl,,O,,,,test
US20070219187A1,Fc1ccc(C#CC2CCCNC2)cc1.O=C(Cl)c1ccc(F)cc1>>O=C(c1ccc(F)cc1)N1CCCC(C#Cc2ccc(F)cc2)C1,,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US20110144066A1,CCCCc1ccccc1.O=S(=O)(O)Cl>>CCCCc1ccc(S(=O)(=O)Cl)cc1,,ClC(Cl)Cl,,,,test
US20100310512A1,COc1cc(CBr)c(-c2c(CBr)cc(OC)cc2OC)c(OC)c1>>Oc1cc(O)c(-c2c(O)cc(O)cc2CBr)c(CBr)c1,,ClCCl,,BrB(Br)Br,,test
US20150218186A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)n2cc(-c3cnc(C)c4cnc(N[C@@H]5CCCC[C@@H]5N)nc34)c3ccc(C(F)(F)F)cc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3cnc(C)c4cnc(N[C@H]5CCCC[C@H]5NC(=O)OC(C)(C)C)nc34)c3ccc(C(F)(F)F)cc32)cc1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20020094935A1,COC(=O)c1sc(C(F)(F)F)cc1OC>>COc1cc(C(F)(F)F)sc1C(=O)O,,CO,O,[K+].[OH-],,test
US20120028961A1,O=C(CBr)c1ccccc1.Sc1cccc(Br)c1>>O=C(CSc1cccc(Br)c1)c1ccccc1,,CCO,,O,[K+].[OH-],test
US20050261279A1,C=O.O=S(=O)(c1ccc(F)cc1)c1cc(I)c2c(c1)CCNCC2>>CN1CCc2cc(S(=O)(=O)c3ccc(F)cc3)cc(I)c2CC1,,ClCCl,,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20120277186A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Ic1ccc2c(c1)C1CC=NC1CO2>>CC(C)(C)OC(=O)N1CCC2c3cc(I)ccc3OCC21,,ClCCl,,,,test
US20130172292A1,O=S(=O)(OCC(F)F)C(F)(F)F.c1ccc(COc2ccc(-c3n[nH]c4cccnc34)cc2)cc1>>Oc1ccc(-c2nn(CC(F)F)c3cccnc23)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20050113580A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Oc1cccc(N2CCNCC2)n1>>CC(C)(C)OC(=O)N1CCN(c2cccc(O)n2)CC1,,C1COCCO1,,O,,test
US05304551,COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C>>C[C@H](CCCO)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,O,,test
US20160137696A1,CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCC(=O)NCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]>>[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCCNC(=O)CCCCCCCCCCCCCCCCC(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150299169A1,CC1(C)Cc2nc(C3CCN(c4ncc(O)cn4)CC3)c([C@@H](F)c3ccc(C(F)(F)F)cc3)c(C3CCC(F)(F)CC3)c2[C@@H](O)C1.Cc1ccc(S(=O)(=O)OC[C@H]2COC(C)(C)O2)cc1>>CC1(C)Cc2nc(C3CCN(c4ncc(OC[C@H]5COC(C)(C)O5)cn4)CC3)c([C@@H](F)c3ccc(C(F)(F)F)cc3)c(C3CCC(F)(F)CC3)c2[C@@H](O)C1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US06114163,CC(=O)O.CSCCC(N)C(=O)O>>CSCCC(NC(C)=O)C(=O)O,,CC(=O)O,,CC(=O)OC(C)=O,,test
US08119805B2,CN1CCC(N2CCNCC2)CC1.O=S(=O)(Cl)CC1CCCCN1S(=O)(=O)c1cccc(C(F)(F)F)c1>>CN1CCC(N2CCN(S(=O)(=O)CC3CCCCN3S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)CC1,,ClCCl,,CCN(CC)CC,,test
US20070021424A1,CC(C)(C)OC(=O)N1CCC(CO)C1.Oc1cccc2ccccc12>>CC(C)(C)OC(=O)N1CCC(COc2cccc3ccccc23)C1,,C1CCOC1,Cc1ccccc1,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20100210619A1,Nc1ccc(S(N)(=O)=O)cc1.O=C(O)c1cc(NC2CCCCC2)ncn1>>NS(=O)(=O)c1ccc(NC(=O)c2cc(NC3CCCCC3)ncn2)cc1,,CO,,,,test
US20070185324A1,Cc1ccc2c(Cl)nccc2c1[N+](=O)[O-].Nc1cccc(C(F)(F)F)c1>>Cc1ccc2c(Nc3cccc(C(F)(F)F)c3)nccc2c1[N+](=O)[O-],,CC(C)O,,,,test
US20060052408A1,Cc1ccc(S(=O)(=O)O[C@H](CCOCc2ccccc2)CC(C#N)c2cccc(Cl)c2)cc1>>N#C[C@]1(c2cccc(Cl)c2)C[C@@H]1CCOCc1ccccc1,,CN(C)C=O,,O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20160244417A1,CI.O=C(O)[C@@H]1CCC(F)(F)C[C@H]1c1csc(-c2cncc(Cl)c2)n1>>COC(=O)[C@@H]1CCC(F)(F)C[C@H]1c1csc(-c2cncc(Cl)c2)n1,,Cc1ccccc1,,C1CCC2=NCCCN2CC1,,test
US20120208797A1,CC(C)(C)[Si](C)(C)OCC(=O)c1ccccc1>>CC(C)(C)[Si](C)(C)OCC(O)c1ccccc1,,CO,,[BH4-].[Na+],,test
US05506242,COc1ccc(S(=O)(=O)N(Cc2ccccc2)[C@@H](C(=O)NOCc2ccccc2)C(O)C(C)C)cc1>>COc1ccc(S(=O)(=O)N(Cc2ccccc2)[C@@H](C(=O)NO)C(O)C(C)C)cc1,[Pd],CCO,,,,test
US20090221555A1,CNC(=O)c1cccc(C)c1Nc1nc(Cl)ncc1Cl.COCCN1C(=O)CCCc2ccc(N)cc21>>CNC(=O)c1cccc(C)c1Nc1nc(Nc2ccc3c(c2)N(CCOC)C(=O)CCC3)ncc1Cl,,CC(C)O,,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US20130274467A1,Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)cn1.NCC1CC(=O)NO1>>Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC2CC(=O)NO2)cn1,,CCOC(C)=O,CN(C)C=O,O=C(n1ccnc1)n1ccnc1,,test
US20130317001A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)c1cc(Cl)c(OCC2(C(F)(F)F)CCCCC2)cc1F>>CC(C)(C)OC(=O)c1cc(Cl)c(OCC2(C(F)(F)F)CCCCC2)cc1F,CN(C)c1ccncc1,CC(C)(C)O,,,,test
US05292747,CCOC(=O)c1cc2ccccc2[nH]1.CN(C)C=O.Cc1ccc(S(=O)(=O)OC2CC(=O)N(Cc3ccccc3)C2)cc1>>CCOC(=O)c1cc2ccccc2n1CC1CC(=O)N(Cc2ccccc2)C1,,O,,Cl,[H-].[Na+],test
US20020077486A1,CC(=O)Nc1cccc(CO)c1>>CC(=O)Nc1cccc(C=O)c1,O=[Mn]=O,Cc1ccccc1,,,,test
US20150152118A1,CC1CN(C(=O)OC(C)(C)C)CCN1CCCC#N.Cl>>CC1CNCCN1CCCC#N.Cl,,CCOCC,,,,test
US20090156603A1,COc1cccc(Sc2cnc(NC(=S)NC(=O)c3ccccc3)c(Oc3ccc(F)cc3Br)c2)c1>>COc1cccc(Sc2cnc(NC(N)=S)c(Oc3ccc(F)cc3Br)c2)c1,,O,,CCO,[Na+].[OH-],test
US20030018029A1,O=C(Cc1cccs1)N1CCOCC1>>c1csc(CCN2CCOCC2)c1,,C1CCOC1,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20120165544A1,CC(=O)n1ccc(O)n1.O=[N+]([O-])c1ccccc1CBr>>O=[N+]([O-])c1ccccc1COc1cc[nH]n1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030186985A1,CN(C)C=O.O=C(O)CCCCC(=O)c1ccccc1>>NC(=O)CCCCC(=O)c1ccccc1,,C1CCOC1,,O=C(Cl)C(=O)Cl,,test
US20150087825A1,CC(CC1(O)CCOCC1)(NS(=O)C(C)(C)C)c1cc(Br)ccc1F>>CC(N)(CC1(O)CCOCC1)c1cc(Br)ccc1F,,ClCCl,,Cl,,test
US20120283266A1,N[C@@H]1C[C@H]1c1ccccc1>>N[C@@H]1C[C@H]1c1ccccc1,,CO,,Cl,C[O-].[Na+],test
US20150342185A1,Cc1cc([N+](=O)[O-])ccc1C1C(=O)C2CCC(C2)C1=O>>Cc1cc(N)ccc1C1C(=O)C2CCC(C2)C1=O,[Pd],CCOC(C)=O,,CCO,,test
US20090253689A1,OCc1cc2nccn2cc1-c1ccc(Cl)cc1Cl>>O=Cc1cc2nccn2cc1-c1ccc(Cl)cc1Cl,O=[Mn]=O,ClC(Cl)Cl,,,,test
US20040152742A1,CCOC(=O)CBr.Oc1ccc(C(F)(F)F)cc1Cl>>CCOC(=O)COc1ccc(C(F)(F)F)cc1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040087798A1,Nc1ccc(NC(=O)c2cccc3c2Cc2ccccc2-3)cc1.O=Cc1ccccn1>>O=C(Nc1ccc(NCc2ccccn2)cc1)c1cccc2c1Cc1ccccc1-2,,ClCCCl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05739129,Cc1nn(C)c(C)c1Nc1ccccc1[N+](=O)[O-]>>Cc1nn(C)c(C)c1Nc1ccccc1N,[Pd],CCOC(C)=O,,,,test
US05310743,O=C(N(Cc1ccnc2ccccc12)[C@H]1CCN[C@H](Cc2ccccc2)C1)C(F)(F)F.O=C(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CC[C@H](N(Cc2ccnc3ccccc23)C(=O)C(F)(F)F)C[C@H]1Cc1ccccc1,,ClCCl,,CCN(CC)CC,O=C1OCCN1P(=O)(Cl)N1CCOC1=O,test
US20090298894A1,O=[N+]([O-])c1ccc(Cl)c([N+](=O)[O-])c1C(F)(F)F>>Nc1ccc(Cl)c([N+](=O)[O-])c1C(F)(F)F,[Fe],CCOC(C)=O,Cl,,,test
US20100029684A1,COC[C@H](C1CC1)n1cc(C#N)nc(Nc2cc(C)c(OC)nc2C)c1=O>>COC[C@H](C1CC1)n1cc(C#N)nc(Nc2cc(C)c(O)nc2C)c1=O,,CC(=O)O,,,,test
US20080090854A1,C[Mg]Cl.O=Cc1ccc(C(F)(F)F)nc1>>CC(O)c1ccc(C(F)(F)F)nc1,,C1CCOC1,,[Cl-].[NH4+],,test
US20090281062A1,O=C(Oc1cccc(I)c1OC(=O)C(F)(F)F)C(F)(F)F.O=C(c1ccccc1)N1CCC(=NO)CC1>>O=NC1(OC(=O)C(F)(F)F)CCN(C(=O)c2ccccc2)CC1,,ClCCl,,,,test
US20110053940A1,COCCCc1cc(CN(C(=O)[C@@H]2CN(C(=O)OC(C)(C)C)CC[C@H]2c2cc(=O)n(C)c(C)c2C)C2CC2)cc(OCCOC)c1>>COCCCc1cc(CN(C(=O)[C@@H]2CNCC[C@H]2c2cc(=O)n(C)c(C)c2C)C2CC2)cc(OCCOC)c1,,ClCCl,,Cl,,test
US20060142357A1,CC(C)(C)OC(=O)NC12CCC(c3ccc(S(C)(=O)=O)cc3)(CC1)CC2>>CS(=O)(=O)c1ccc(C23CCC(N)(CC2)CC3)cc1,O,ClCCl,,O=C(O)C(F)(F)F,,test
US20080269218A1,C#CC(C)c1cc(C(=O)Nc2ccc(CN3CCOCC3)cc2)c(OCC=C)cc1OCC=C.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>C#CC(C)c1cc(C(=S)Nc2ccc(CN3CCOCC3)cc2)c(OCC=C)cc1OCC=C,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20150284411A1,C=CC[Mg]Br.O=C1CO[C@@H]2[C@H](Oc3nc4nc(-c5ccc(-c6ccccc6)cc5)c(Cl)cc4[nH]3)CO[C@H]12>>C=CC[C@@]1(O)CO[C@@H]2[C@H](Oc3nc4nc(-c5ccc(-c6ccccc6)cc5)c(Cl)cc4[nH]3)CO[C@@H]21,,C1CCOC1,,CCOCC,,test
US20140031552A1,CC(C)(C)OC(=O)Nc1ccco1.COC(=O)C#CC(=O)OC>>COC(=O)c1c(O)ccc(NC(=O)OC(C)(C)C)c1C(=O)OC,,Cc1ccccc1,,,,test
US20120309791A1,Cc1ccc(-c2cc(NC(=O)c3cc(NC(=O)c4cc(-c5ccc(C)cc5)n(C5CCCCO5)n4)n(C4CCCCO4)n3)nn2C2CCCCO2)cc1>>Cc1ccc(-c2cc(CNc3cc(CNc4cc(-c5ccc(C)cc5)[nH]n4)n[nH]3)n[nH]2)cc1,,C1CCOC1,,CO,Cl,test
US20090176823A1,COC(=O)C1=C(c2ccc(O)cc2)C[C@@H]2CC[C@H]1N2C(=O)OC(C)(C)C.OCc1cc(-c2c(F)ccc(F)c2Cl)no1>>COC(=O)C1=C(c2ccc(OCc3cc(-c4c(F)ccc(F)c4Cl)no3)cc2)C[C@@H]2CC[C@H]1N2C(=O)OC(C)(C)C,,Cc1ccccc1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20150087646A1,CC(C)(C)OC(=O)NNc1c(Cl)ccc(CNC(=O)C(C)(C)C)c1F.O=C=NC(=O)c1c(F)cccc1Cl>>CC(C)(C)C(=O)NCc1ccc(Cl)c(-n2nc(-c3c(F)cccc3Cl)[nH]c2=O)c1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100184815A1,CCCCCCCCn1c(CO)nn(Cc2ccc(C)cc2)c1=O.COc1cc(C(=O)O)ccc1OC(C)(C)C(=O)OC(C)(C)C>>CCCCCCCCn1c(COC(=O)c2ccc(OC(C)(C)C(=O)O)c(OC)c2)nn(Cc2ccc(C)cc2)c1=O,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20090275037A1,COc1cccc(C=O)c1OC.O=[N+]([O-])O>>COc1ccc([N+](=O)[O-])c(C=O)c1OC,,O,,,,test
US20120202785A1,C[C@H](N)c1nc2cc(F)ccc2n1-c1ccccc1.Clc1ncnc2c1ncn2C1CCCCO1>>C[C@H](Nc1ncnc2nc[nH]c12)c1nc2cc(F)ccc2n1-c1ccccc1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20080146607A1,CC(C)[Si](C(C)C)(C(C)C)n1ccc2cc(Br)ccc21.COC(=O)[C@]1(Cc2ccccc2)CCCN1C(=O)OC(C)(C)C>>CC(C)[Si](C(C)C)(C(C)C)n1ccc2cc(C(=O)C3(Cc4ccccc4)CCCN3C(=O)OC(C)(C)C)ccc21,,C1CCOC1,,[Li]C(C)(C)C,,test
US20050107389A1,Fc1ccc2c(N3CCNCC3)c(F)sc2c1.O=C1NC(=O)c2c(CCCCBr)cccc21>>O=C1NC(=O)c2c(CCCCN3CCN(c4csc5cc(F)ccc45)CC3)cccc21,,ClCCl,,CC#N,CCN(CC)CC,test
US20080113946A1,COc1cc(N)cc(OC)c1.CSc1nc(Cl)c2c(n1)COC2>>COc1cc(Nc2nc(SC)nc3c2COC3)cc(OC)c1,,CC(C)O,,,,test
US20040102509A1,Cc1cc(C)c(C=O)[nH]1.O=C1Cc2cc(Cl)ccc2N1>>O=C1Nc2ccc(Cl)cc2C1=Cc1ccc[nH]1,,CCO,,C1CCNCC1,,test
US20050272669A1,C=CC(=O)OCc1ccccc1.NCc1ccccc1>>O=C(CCNCc1ccccc1)OCc1ccccc1,,CCO,,,,test
US20060173004A1,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cc2ncccc2cc1[N+](=O)[O-]>>COC(=O)/C=C/c1cc2ncccc2cc1[N+](=O)[O-],,Cc1ccccc1,,,,test
US20150353537A1,CC(C)(C)OC(=O)N1CC(C)(C)c2ncc(C(O)c3ccc(F)cc3)cc21>>CC1(C)CNc2cc(C(O)c3ccc(F)cc3)cnc21,,CO,Cl,,,test
US20090192144A1,CS(=O)(=O)Cl.N#Cc1ccc(C(O)COCc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)cc1>>CS(=O)(=O)OC(COCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)c1ccc(C#N)cc1,,ClCCl,,CCN(CC)CC,,test
US05880147,CC(C)(C)c1ccc(C#N)cc1[N+](=O)[O-]>>CC(C)(C)c1ccc(C#N)cc1N,,CCCCCC,CCOC(C)=O,,,test
US20130245002A1,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.Fc1cc(Br)cnc1F>>Cn1cc(-c2cnc(F)c(F)c2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20120309757A1,Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)OC(C)(C)C)cc2)c2ccc(C(=O)N[C@@H](C)c3ccc(Br)cc3)cc12>>Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3ccc(Br)cc3)cc12,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100286149A1,CCCN(CCC)S(=O)(=O)c1ccc(C(=O)O)cc1.Nc1cc(Cl)ccc1-c1noc(=O)[nH]1>>CCCN(CCC)S(=O)(=O)c1ccc(C(=O)Nc2cc(Cl)ccc2-c2nc(=O)o[nH]2)cc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20150291595A1,N.O=C(NCCCN1CCOCC1)c1c(Cl)ncnc1Cl>>Nc1ncnc(Cl)c1C(=O)NCCCN1CCOCC1,,C1COCCO1,,Cl,,test
US20100311966A1,CCc1[nH]c(C(=O)O)nc1Cl.COC(=O)c1coc(-c2ccc(N)cc2)n1>>CCc1[nH]c(C(=O)Nc2ccc(-c3nc(C(=O)OC)co3)cc2)nc1Cl,,c1ccncc1,,O=S(Cl)Cl,,test
US20120190678A1,CC(C)(C)OC(=O)N1CCC(CBr)CC1.NC(=O)c1n[nH]c2c1CCc1cnc(I)nc1-2>>CC(C)(C)OC(=O)N1CCC(Cn2nc(C(N)=O)c3c2-c2nc(I)ncc2CC3)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20070208033A1,CCCN(CCC)Cc1ccc(NC)cc1.O=C(O)c1ccc(CN(Cc2ncc[nH]2)Cc2ncc[nH]2)cc1>>CCCN(CCC)Cc1ccc(N(C)C(=O)c2ccc(CN(Cc3ncc[nH]3)Cc3ncc[nH]3)cc2)cc1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20150105373A1,CCC(NC(=O)N1CC(=O)Nc2cccnc21)c1ccc(O)cc1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCC(NC(=O)N1CC(=O)Nc2cccnc21)c1ccc(OS(=O)(=O)C(F)(F)F)cc1,,c1ccncc1,,,,test
US04521430,CCN(C)CCN1C(=O)[C@H](O)[C@H](c2ccc(OC)cc2)Sc2ccccc21.O=C(Cl)c1ccc(Cl)c([N+](=O)[O-])c1.O=C(O)C(=O)O>>CCN(C)CCN1C(=O)[C@H](OC(=O)c2ccc(Cl)c([N+](=O)[O-])c2)[C@H](c2ccc(OC)cc2)Sc2ccccc21.O=C(O)C(=O)O,,CC(C)=O,ClCCl,CCN(CC)CC,Cl,test
US20140249133A1,CCOc1cc(F)c(Cn2nc(-c3nccc(Nc4ccncc4)n3)c3ccccc32)c(F)c1.O=S1OCCO1>>CCOc1cc(F)c(Cn2nc(-c3nccc(N(CCO)c4ccncc4)n3)c3ccccc32)c(F)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160016966A1,CC(=O)Nc1cc(-c2cn(C)c(=O)c3cc(CBr)oc23)ccn1.O=C1CCNCCN1>>CC(=O)Nc1cc(-c2cn(C)c(=O)c3cc(CN4CCNC(=O)CC4)oc23)ccn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US06180718B2,CC(C)[Si](Cl)(Cl)C(C)C.COCOc1ccc(Br)cc1>>COCOc1ccc([Si](Cl)(C(C)C)C(C)C)cc1,,C1CCOC1,,CCOCC,[Li]CCCC,test
US20090269301A1,CCOC(=O)C(=O)Cc1c[nH]c2ccccc12.NCCCn1ccnc1.O=Cc1ccccc1F>>O=C1C(O)=C(c2c[nH]c3ccccc23)C(c2ccccc2F)N1CCCn1ccnc1,,CCO,,,,test
US06339162B1,CC(=O)OC[C@H]1O[C@@H](Oc2ccccc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>OC[C@H]1O[C@@H](Oc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O,,CC(=O)O,,CO,C[O-].[Na+],test
US20130150339A1,CC1(C)OB(c2ccccc2O)OC1(C)C.COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(Cl)nccc3c2)cc1>>COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(-c4ccccc4O)nccc3c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20140343092A1,Cc1c(-c2c(C(OC(C)(C)C)C(=O)O)n(C)c(=O)c3[nH]ccc23)ccc2c1CCCO2.O=[N+]([O-])c1ccc(CBr)cc1>>Cc1c(-c2c(C(OC(C)(C)C)C(=O)O)n(C)c(=O)c3c2ccn3Cc2ccc([N+](=O)[O-])cc2)ccc2c1CCCO2,,CC#N,O,,,test
US05374609,BrP(Br)Br.OCC#CCc1ccccc1>>BrCC#CCc1ccccc1,,Cc1ccccc1,,c1ccncc1,,test
US20020143022A1,COC(=O)c1ccc2c(C)c[nH]c2c1.O=C(Cl)c1ccc(Cl)cc1Cl>>COC(=O)c1ccc2c(C)c(C(=O)c3ccc(Cl)cc3Cl)[nH]c2c1,,ClCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20060241115A1,COC(=O)c1ccc(I)c2cc(O)ccc12.C[Sn](C)(C)C>>COC(=O)c1ccc(C)c2cc(O)ccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US05008280,CCCSCCCl.Nc1nc2ccc(OC(F)(F)F)cc2s1>>CCCSCCn1c(=N)sc2cc(OC(F)(F)F)ccc21.Cl,,CCC(C)=O,,,,test
US20160052884A1,CCOC(=O)c1nc2ccc(N)cc2[nH]1.COc1cn(C(C(=O)O)C(C)C)c(=O)cc1-c1cc(Cl)ccc1C#N>>CCOC(=O)c1nc2ccc(NC(=O)C(C(C)C)n3cc(OC)c(-c4cc(Cl)ccc4C#N)cc3=O)cc2[nH]1,,CN(C)C=O,,CC(C)N=C=NC(C)C,,test
US20140030221A1,CC(C)(C)OC(=O)N[C@@H](CO)C(=O)O.CC1(CBr)COC1>>CC1(COC[C@H](NC(=O)OC(C)(C)C)C(=O)O)COC1,,CS(C)=O,,[H-].[Na+],,test
US20050165006A1,O=CN1CCNCC1.O=[N+]([O-])c1ccc2nc(Br)cc(Br)c2c1>>O=[N+]([O-])c1ccc2nc(N3CCNCC3)cc(Br)c2c1,,CN(C)C=O,,O,,test
US20020037889A1,Brc1cccc(Br)n1.NCC1CC1>>Brc1cccc(NCC2CC2)n1,,CCN(C(C)C)C(C)C,,,,test
US20050267148A1,CC(C)(C)OC(=O)c1ccccc1CCBr.Cc1cc2nc(S)[nH]c2cc1C>>Cc1cc2nc(SCc3ccccc3C(=O)OC(C)(C)C)[nH]c2cc1C,,CN(C)C=O,,CCN(CC)CC,O,test
US20020032168A1,Clc1nc(Cl)c2ncn(C3CCCCO3)c2n1.NCc1cccc2ccccc12>>Clc1nc(NCc2cccc3ccccc23)c2ncn(C3CCCCO3)c2n1,,CC#N,,CCN(CC)CC,,test
US07273878B2,CC(CCCCS)=C(F)F.O=C(Cl)c1cc2ccccc2s1>>CC(CCCCSC(=O)c1cc2ccccc2s1)=C(F)F,,O,,C1CCOC1,CCN(CC)CC,test
US20090264401A1,CC1(C)OC(=O)C(C(=O)C2CCC(F)(F)C2)C(=O)O1.CO>>COC(=O)CC(=O)C1CCC(F)(F)C1,,Cc1ccccc1,,,,test
US06858591B2,COc1ccc(Cn2c(=O)ccn([C@@H]3OC([C@H](O)[C@H](NCCCNC(=O)[C@H](C)NC(=O)OCc4ccccc4)C(=O)OC(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]3O[Si](C)(C)C(C)(C)C)c2=O)cc1>>COc1ccc(Cn2c(=O)ccn([C@@H]3OC([C@H](O)[C@H](NCCCNC(=O)[C@H](C)N)C(=O)OC(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]3O[Si](C)(C)C(C)(C)C)c2=O)cc1,[Pd],CO,,,,test
US20080214558A1,CN1CCN(c2ccc(Nc3nccc(Nc4cccc(CC#N)c4)n3)cc2F)CC1.O=S(=O)(O)c1ccccc1>>CN1CCN(c2ccc(Nc3nccc(Nc4cccc(CC#N)c4)n3)cc2F)CC1.O=S(=O)(O)c1ccccc1,,CCO,,,,test
US20120010228A1,COC(=O)c1cccc(CN2CN(c3ccc(F)cc3)C3(CCN(CCCn4c(=O)[nH]c5ccccc54)CC3)C2=O)c1>>O=C(O)c1cccc(CN2CN(c3ccc(F)cc3)C3(CCN(CCCn4c(=O)[nH]c5ccccc54)CC3)C2=O)c1,,CO,O,[Li+].[OH-],,test
US20090099187A1,COc1ccc(S(=O)(=O)N2CCc3ccccc32)c2c1C[C@@H](NC(=O)C(F)(F)F)CC2>>COc1ccc(S(=O)(=O)N2CCc3ccccc32)c2c1C[C@@H](N)CC2,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US04178449,BrBr.FC(F)(F)c1cccc(-c2ccnc3ccnn23)c1>>FC(F)(F)c1cccc(-c2ccnc3c(Br)cnn23)c1,,ClCCl,,,,test
US04150032,C=CCC1(CCNCC2CCC2)c2cc(OC)ccc2CCC12OCCO2>>C=CCC12CCN(CC3CCC3)C1=CCc1ccc(OC)cc12,,CCO,,Cl,,test
US20110275797A1,COC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1OCc1ccccc1>>COC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(C2CCNCC2)ccc1OCc1ccccc1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US05756508,CCCN1C[C@@H](C(=O)OC)C(=O)C[C@@H]1C>>CCCN1CCC(=O)CC1C,,Cl,,[Na+].[OH-],,test
US20160024053A1,COC(=O)c1ccc2c(SC)c[nH]c2c1.Clc1ncc(Br)cn1>>COC(=O)c1ccc2c(SC)cn(-c3ncc(Br)cn3)c2c1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20110076292A1,CC(C)N(N)C(=O)c1cn2c(n1)-c1ccc(Br)cc1OCC2.COCC(=O)Cl>>COCC(=O)NN(C(=O)c1cn2c(n1)-c1ccc(Br)cc1OCC2)C(C)C,,ClCCl,,Cl,Cl,test
US20050261333A1,BrBr.Cc1ccc(-c2nc3cc(Br)cnc3[nH]2)cc1>>BrCc1ccc(-c2nc3cc(Br)cnc3[nH]2)cc1,,CC(=O)O,,,,test
US05061717,CC(=O)c1ccc(CC2SC(=O)NC2=O)cc1.O=Cc1ccccc1>>O=C1NC(=O)C(Cc2ccc(C(=O)/C=C/c3ccccc3)cc2)S1,,CCO,O,Cl,C[O-].[Na+],test
US20130225591A1,Cl.O=[N+]([O-])c1ncn2c(C(F)(F)F)csc12>>Cl.Nc1ncn2c(C(F)(F)F)csc12,[Pd],CCOCC,,CCOC(C)=O,,test
US20100160280A1,COc1cnc(Oc2ccc(Nc3ccc(C)cn3)cc2)c(Br)c1.OB(O)c1ccnc(F)c1>>COc1cnc(Oc2ccc(Nc3ccc(C)cn3)cc2)c(-c2ccnc(F)c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US05703106,CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)O.Fc1nc(F)nc(F)n1>>CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)F,,ClCCl,,c1ccncc1,,test
US04052455,ClP(Cl)(Cl)(Cl)Cl.O=C(NS(=O)(=O)C=Cc1ccc([N+](=O)[O-])cc1)c1ccccc1>>O=[N+]([O-])c1ccc(C=CS(=O)(=O)N=C(Cl)c2ccccc2)cc1,,c1ccccc1,,,,test
US04294960,CCOC(=O)C(=NOC(C)C)C(C)=O.O=S(=O)(Cl)Cl>>CCOC(=O)C(=NOC(C)C)C(=O)CCl,,CC(=O)O,,,,test
US20080139558A1,Cl.Nc1cccc(Cl)c1.O=N[O-]>>Cl.NNc1cccc(Cl)c1,,Cl,O,Cl[Sn]Cl,,test
US20070219229A1,CCI.CCOC(=O)c1cnc(Cl)c2cc[nH]c12>>CCOC(=O)c1cnc(Cl)c2ccn(CC)c12,,CN(C)C=O,,[H-].[Na+],,test
US20060025423A1,C#CCO.COc1nc(Cl)cnc1N(COCCO[Si](C)(C)C)S(=O)(=O)c1cccc(Cl)c1Cl>>C#CCOc1cnc(NS(=O)(=O)c2cccc(Cl)c2Cl)c(OC)n1,,CN(C)C=O,,[H-].[Na+],,test
US20120046306A1,O=C1Cc2cnc(Cl)cc2N1.O=Cc1cccc(Cl)c1F>>O=C1Nc2cc(Cl)ncc2/C1=C/c1cccc(Cl)c1F,,CO,,C1CCNCC1,,test
US20140112945A1,COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)Cc4c[nH]c5ccccc45)CC3)C(=O)[C@H]3CCCC[C@@H]23)cc1OC.O=C(O)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4c[nH]c5ccccc45)NC(=O)c4c[nH]c5c(-c6c(OCC7CC7)ccc7c6OCO7)ncnc45)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC,,CN(C)C=O,O,ClCCCl,On1nnc2ccccc21,test
US04342692,COc1ccc(CC(CCC2(CCc3ccc(C)cc3)OCCO2)[N+](=O)[O-])cc1OC>>COc1ccc(CC(N)CCC2(CCc3ccc(C)cc3)OCCO2)cc1OC,,C1CCOC1,,[H-].[Na+],,test
US20080221192A1,Cc1[nH]c(C=O)c(C)c1C(=O)O.O=C1Cc2ccc(NC(=O)c3ccccc3)cc2N1>>Cc1[nH]c(C=C2C(=O)Nc3cc(NC(=O)c4ccccc4)ccc32)c(C)c1C(=O)O,C1CCNCC1,CCO,,,,test
US20120245026A1,CNC1(C#N)CCN(N(C)C)CC1.Cc1cc(C)c(CC(=O)Cl)c(C)c1>>Cc1cc(C)c(CC(=O)N(C)C2(C#N)CCN(N(C)C)CC2)c(C)c1,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20130116430A1,CC[C@@H](N)CN1C(=O)c2ccccc2C1=O.N#Cc1cc(F)c(Cl)nc1Nc1ccc2ncccc2c1>>CC[C@H](CN1C(=O)c2ccccc2C1=O)Nc1nc(Nc2ccc3ncccc3c2)c(C#N)cc1F,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20140194431A1,O=C1c2c(OCc3ccccc3)c(=O)nc(CC3(c4cccc5ccccc45)CCCC3)n2CCN1C1COC1>>O=C1c2c(O)c(=O)nc(CC3(c4cccc5ccccc45)CCCC3)n2CCN1C1COC1,[Pd],CCO,,,,test
US20120010191A1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=CC1=C(Cl)C2CCC1C2>>CCOC(=O)/C=C/C1=C(Cl)C2CCC1C2,,ClCCl,,,,test
US20070004772A1,COc1nc(C(F)(F)F)ccc1CCl.O=c1[nH]nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)ccn12>>COc1nc(C(F)(F)F)ccc1Cn1nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)ccn2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050214797A1,O=C(O)C1Cc2c(ccc3c2ccn3C(=O)OCC2c3ccccc3-c3ccccc32)N1.O=C(Oc1c(F)c(F)c(F)c(F)c1F)C(F)(F)F>>O=C(Oc1c(F)c(F)c(F)c(F)c1F)C1Cc2c(ccc3c2ccn3C(=O)OCC2c3ccccc3-c3ccccc32)N1,,CN(C)C=O,,CCN(CC)CC,,test
US20060135773A1,BrCc1ccccc1.O=C1NS(=O)(=O)c2ccccc21>>O=C1c2ccccc2S(=O)(=O)N1Cc1ccccc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20060040985A1,COC(=O)c1ccc(S(=O)(=O)CC2(O)CCN(C(=O)OC(C)(C)C)CC2)cc1.Cl>>COC(=O)c1ccc(S(=O)(=O)CC2(O)CCNCC2)cc1.Cl,,CCOC(C)=O,,,,test
US20070232627A1,CN(C(=O)c1ccc(Sc2ccc(NC(=O)OCC(Cl)(Cl)Cl)cc2)c([N+](=O)[O-])c1)c1ccc(F)cc1>>CN(C(=O)c1ccc(Sc2ccc(NC(=O)OCC(Cl)(Cl)Cl)cc2)c(N)c1)c1ccc(F)cc1,[Fe],,,[Cl-].[NH4+],,test
US04430346,CCCC(=O)OC(=O)CCC.Cl.N=C(N)NCCCC[C@H](O)CC(N)=O>>CCCC(=O)O[C@@H](CCCCNC(=N)N)CC(N)=O.Cl,,c1ccncc1,,CN(C)C=O,,test
US20090298878A1,CCO.O=S(=O)(c1ccc(F)cc1)N1CCC(=NOCc2cccc(C(F)(F)F)c2)CC1>>CCOc1ccc(S(=O)(=O)N2CCC(=NOCc3cccc(C(F)(F)F)c3)CC2)cc1,,C1CCOC1,,[Na],,test
US04185115,CS(=O)(=O)Cl.OCCCc1ccc(OCc2ccccc2)cc1>>CS(=O)(=O)OCCCc1ccc(OCc2ccccc2)cc1,,ClCCl,,CCN(CC)CC,,test
US20100144758A1,CCCc1cn(-c2cccc(C)c2)c2ncnc(Cl)c12.NC1CCOCC1>>CCCc1cn(-c2cccc(C)c2)c2ncnc(NC3CCOCC3)c12,,CCO,,CC(=O)[O-].[Na+],,test
US20160244475A1,CC1(C)O[C@@H]2[C@@H](C(=O)c3ccc(F)c(F)c3)O[C@@H](n3ccc4c(Cl)ncnc43)[C@@H]2O1.C[Mg]Br>>CC1(C)O[C@@H]2[C@@H]([C@](C)(O)c3ccc(F)c(F)c3)O[C@@H](n3ccc4c(Cl)ncnc43)[C@@H]2O1,,C1CCOC1,,[Cl-].[NH4+],,test
US20110312965A1,COC(=O)/C=C/c1ccc(-c2ccc(OCC#N)c(C34CC5CC(CC(C5)C3)C4)c2)cc1>>N#CCOc1ccc(-c2ccc(/C=C/C(=O)O)cc2)cc1C12CC3CC(CC(C3)C1)C2,,C1CCOC1,O,[Li]O,,test
US08664214B2,O=Cc1cnccc1Br.OB(O)c1ccccc1>>O=Cc1cnccc1-c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20150252135A1,CC(C)c1cccc(C(C)C)c1N1C(=O)c2cc(Oc3ccc(C(C)(C)C)cc3)c3c4cccc5c(Br)ccc(c6c(Oc7ccc(C(C)(C)C)cc7)cc(c2c36)C1=O)c54.Nc1ccccc1S>>CC(C)c1cccc(C(C)C)c1N1C(=O)c2cc(Oc3ccc(C(C)(C)C)cc3)c3c4cccc5c(Sc6ccccc6N)ccc(c6c(Oc7ccc(C(C)(C)C)cc7)cc(c2c36)C1=O)c54,,CN1CCCC1=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US05565485,CC(C)c1ccc(S(N)(=O)=O)cc1.CCCc1cc(CO[Si](C)(C)C(C)(C)C)ccc1OC(C(=O)O)c1ccc2c(c1)OCO2>>CCCc1cc(CO[Si](C)(C)C(C)(C)C)ccc1OC(C(=O)NS(=O)(=O)c1ccc(C(C)C)cc1)c1ccc2c(c1)OCO2,,C1CCOC1,CCOC(C)=O,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US20100305133A1,COC(=O)c1c(N)c(N)cc(Br)c1OC.O=CC(=O)c1ccc(F)cc1>>COC(=O)c1c(OC)c(Br)cc2ncc(-c3ccc(F)cc3)nc12,,CO,,O,,test
US20140005192A1,CSc1nc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3ncc(Cl)cc23)ncc1F.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1nc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3ncc(Cl)cc23)ncc1F,,ClCCl,,,,test
US20030069434A1,CNCCCOCc1ccccc1.C[C@]12C[C@H](F)[C@@H]3c4ccc(O)cc4C[C@@H](CCCCCI)[C@H]3[C@@H]1CC[C@@H]2O>>CN(CCCCC[C@@H]1Cc2cc(O)ccc2[C@H]2[C@@H](F)C[C@]3(C)[C@@H](O)CC[C@H]3[C@H]12)CCCOCc1ccccc1,,CN1CCCC1=O,,[Cl-].[Na+],,test
US20150353553A1,Cc1cccc(-c2nc(C(=O)O)nc3nc(N4CCOCC4)n(C[C@@H]4CC[C@@H](C)CC4)c23)c1.NN>>Cc1cccc(-c2nc(C(=O)NN)nc3nc(N4CCOCC4)n(C[C@@H]4CC[C@@H](C)CC4)c23)c1,CN(C)C=O,ClCCl,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US20140303186A1,COC(=O)Cc1c(C)n(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)c2ccccc12>>Cc1c(CC(=O)O)c2ccccc2n1Cc1ccc(NC(=O)c2ccc3ccccc3c2)cc1,,O,,C1CCOC1,[Li+].[OH-],test
US20070232590A1,O=C1CCCC1.O=C1CCCN1c1cnc(Oc2ccc3c(c2)CCNCC3)cn1>>O=C1CCCN1c1cnc(Oc2ccc3c(c2)CCN(C2CCCC2)CC3)cn1,CC(=O)O,CO,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05274116,CC(NC(=O)OCc1ccccc1)C(=O)O.Nn1cccc1>>CC(NC(=O)OCc1ccccc1)C(=O)Nn1cccc1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05084460,C1CCOC1.CCOCC.Nc1c(F)c(N)c(F)c(F)c1F.Nc1cc(O)c(C(=O)O)cc1Cl.O=C(n1ccnc1)n1ccnc1>>Nc1cc(O)c(C(=O)NC2CN3CCC2CC3)cc1Cl,,C1CCOC1,CCOCC,Cl,Cl,test
US20150291549A1,COc1cc(CO)ccn1.O=S(Cl)Cl>>COc1cc(CCl)ccn1.Cl,,ClCCl,,,,test
US20040082571A1,Nc1cc(-c2ccco2)[nH]n1.O=C(CCl)N1CCN(c2ccc(F)cc2)CC1>>Nc1cc(-c2ccco2)nn1CC(=O)N1CCN(c2ccc(F)cc2)CC1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20020028801A1,CC(C)CC(CNC(Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(C)(C)C)NC(=O)OC(C)(C)C.Cl.ClCCl>>CC(C)CC(N)CNC(Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(C)(C)C.Cl.Cl,,CCOCC,ClCCl,O=C(O)C(F)(F)F,,test
US20150051395A1,COC(=O)c1c(F)cc(NS(=O)(=O)c2ccc(-n3ccnn3)cn2)cc1F>>O=C(O)c1c(F)cc(NS(=O)(=O)c2ccc(-n3ccnn3)cn2)cc1F,,CO,,Cl,[Na+].[OH-],test
US20080261990A1,COCCN(Cc1ccc(SC(C)(C)C(=O)OC(C)(C)C)cc1)c1cc(-c2ccc(C)cc2)ncn1>>COCCN(Cc1ccc(SC(C)(C)C(=O)O)cc1)c1cc(-c2ccc(C)cc2)ncn1,,C1COCCO1,,Cl,,test
US20020019569A1,CC(COCCCCCO)=NOC(C)(C)C.CS(=O)(=O)Cl>>CC(COCCCCCOS(C)(=O)=O)=NOC(C)(C)C,,C1CCOC1,,CCN(CC)CC,Cl,test
US20140038999A1,CC(C)NC(=O)c1cnccc1-c1ccc(Cl)cc1F>>CC(C)n1c(=O)c2cnccc2c2ccc(Cl)cc21,,C1CCOC1,,[H-].[Na+],,test
US20040248951A1,COC(=O)COc1ccc(N(C)Cc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1I>>Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CN(C)c1ccc(OCC(=O)O)c(I)c1,,C1CCOC1,CCO,[Li+].[OH-],,test
US20070060596A1,CCOC(=O)c1cc(C)n(C(C)c2cc(Cl)ccc2O)n1.Fc1ccc(CBr)c(Cl)c1>>CCOC(=O)c1cc(C)n(C(C)c2cc(Cl)ccc2OCc2ccc(F)cc2Cl)n1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130029990A1,COCC(=O)Nc1cc(COc2ccc([N+](=O)[O-])c3cccnc23)ccn1>>COCC(=O)Nc1cc(COc2ccc(N)c3cccnc23)ccn1,[Fe],CC(=O)O,,,,test
US20150087646A1,CC(C)(C)C(=O)NCc1ccc(Cl)c(NN)c1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NNc1cc(CNC(=O)C(C)(C)C)ccc1Cl,,O,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US20060205767A1,COc1ccc(C(C)=O)cc1.O=C(Cl)c1c(F)cc(F)cc1F>>COc1ccc(C(=O)CC(=O)c2c(F)cc(F)cc2F)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20120196864A1,CC(C)Oc1cc(C=O)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F.CNC1=NC(=O)SC1>>CNC1=NC(=O)S/C1=C\c1ccc(OCc2ccc(C(F)(F)F)cc2C(F)(F)F)c(OC(C)C)c1,,CCO,,O,CC(C)(C)[O-].[K+],test
US04401816,C1CCNC1.Cc1cc(C)nc(NC(=O)NS(=O)(=O)Cl)n1>>Cc1cc(C)nc(NC(=O)NS(=O)(=O)N2CCCC2)n1,,ClCCl,,,,test
US20110003820A1,CC(C)NC(=O)c1ccc2n1CCN(C(=O)OC(C)(C)C)C2C>>CC(C)NC(=O)c1ccc2n1CCNC2C,,CO,,Cl,,test
US20120184542A1,CC(C)(C)OC(=O)NCCC(N)c1cccc(Cl)c1.COc1ncc2cc(C(=O)Nc3cc(C(=O)O)ccc3Cl)c(=O)[nH]c2n1>>COc1ncc2cc(C(=O)Nc3cc(C(=O)NC(CCNC(=O)OC(C)(C)C)c4cccc(Cl)c4)ccc3Cl)c(=O)[nH]c2n1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090270361A1,Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1Cc1ccc(C(=O)O)cc1.O=C1CCNCC1>>Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1Cc1ccc(C(=O)N2CCC(=O)CC2)cc1,,CCN(CC)CC,,Cl,O,test
US20150025070A1,CC(C)(C)OC(=O)N1CCC(C(=O)c2ccc3c(c2)OCO3)CC1>>O=C(c1ccc2c(c1)OCO2)C1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160068489A1,CCC(CC)C(=O)Cl.Cc1nc(N)c(C)c(C)c1OCc1ccccc1>>CCC(CC)C(=O)Nc1nc(C)c(OCc2ccccc2)c(C)c1C,,ClCCl,,CCN(CC)CC,,test
US20010034454A1,CCOc1cc(C(=O)Cl)cc(OCC)c1OCC.COc1ccc(-c2cc3ccc(OC)cc3s2)cc1>>CCOc1cc(C(=O)c2c(-c3ccc(OC)cc3)sc3cc(OC)ccc23)cc(OCC)c1OCC,,CCOC(C)=O,ClCCl,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20150051199A1,CC[C@@H](NCC(C)(C)C(=O)OCC(C)C)c1ccc(Cl)c(C(=O)c2cccnc2)c1F>>CC[C@@H](NCC(C)(C)C(=O)O)c1ccc(Cl)c(C(=O)c2cccnc2)c1F,,C1CCOC1,,[Na+].[OH-],,test
US20080146565A1,CSc1nccc(-n2ccc3c(C=O)cccc32)n1>>CSc1nccc(-n2ccc3c(CO)cccc32)n1,,CO,ClCCl,O,[BH4-].[Na+],test
US20020177708A1,CCc1cc(Oc2cccc([N+](=O)[O-])c2)ccc1Cl>>CCc1cc(Oc2cccc(N)c2)ccc1Cl,[Zn],CC(=O)O,,O,,test
US04670447,CN1CCC(c2n[nH]c3ccccc23)CC1.Fc1cccc(C(F)(F)F)c1>>CN1CCC(c2nn(-c3cccc(C(F)(F)F)c3)c3ccccc23)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US20100183564A1,COC(=O)C(C)n1cnc2c(NCCc3c[nH]c4ccccc34)nc(-c3cncc(F)c3)nc21>>CC(CO)n1cnc2c(NCCc3c[nH]c4ccccc34)nc(-c3cncc(F)c3)nc21,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050124599A1,COc1ccc2c(c1)ncn2-c1ccc2cccc(N3CCC(NC(=O)OC(C)(C)C)CC3)c2n1>>COc1ccc2c(c1)ncn2-c1ccc2cccc(N3CCC(N)CC3)c2n1,,O=C(O)C(F)(F)F,,,,test
US05760032,CCc1cc2c(s1)-n1c(CC)nnc1CN=C2c1ccccc1Cl.O=C(Cl)c1ccc(Cl)c(Cl)c1.O=C([O-])O>>CCc1cc(C(=O)c2ccccc2Cl)c(-n2c(CC)nnc2CNC(=O)c2ccc(Cl)c(Cl)c2)s1,,ClC(Cl)Cl,,Cl,,test
US20040048908A1,COC(=O)CCc1conc1-c1ccc(Cl)c(F)c1>>OCCCc1conc1-c1ccc(Cl)c(F)c1,,C1CCOC1,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20070202547A1,COc1ccc2occc2c1.O=CCc1ccccc1>>COc1ccc2oc(C(O)Cc3ccccc3)cc2c1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20150158865A1,C=CC(=O)Cl.NC(=O)c1nnc(N2CCC[C@@H](NC(=O)N3CCCCC3)C2)nc1Nc1ccc(C2CCNCC2)cc1>>CCC(=O)N1CCC(c2ccc(Nc3nc(N4CCC[C@@H](NC(=O)N5CCCCC5)C4)nnc3C(N)=O)cc2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US05270302,N[C@@H](CCCC(=O)O)C(=O)O.O=C(OCc1ccccc1)ON1C(=O)CCC1=O>>O=C(O)CCCC(NC(=O)OCc1ccccc1)C(=O)O,,C1COCCO1,,CCN(CC)CC,O,test
US06127386,CN1CCC[C@H]1COc1cnc(Cl)c(-c2cncnc2)c1.Cl>>CN1CCC[C@H]1COc1cnc(Cl)c(-c2cncnc2)c1.Cl,,CCOCC,,CO,,test
US20100069404A1,CCOC(=O)c1ncsc1Cn1c2c(c3cc(C#N)ccc31)C[C@H](NC(=O)OC(C)C)C2>>CC(C)OC(=O)N[C@H]1Cc2c(n(Cc3scnc3C(=O)O)c3ccc(C#N)cc23)C1,,C1CCOC1,CCO,Cl,[Li+].[OH-],test
US20140235628A1,CC(C)[Si](S)(C(C)C)C(C)C.Cc1c(OS(=O)(=O)C(F)(F)F)ccc2c1COC2=O>>Cc1c(S)ccc2c1COC2=O,,Cc1ccccc1,,,,test
US20120309915A1,CC(=O)c1cccc(C(C)=Nc2c(C)cccc2C)n1.CCCCc1ccccc1N>>CCCCc1ccccc1N=C(C)c1cccc(C(C)=Nc2c(C)cccc2C)n1,,Cc1ccccc1,,,,test
US20130281434A1,COc1cncc(B2OC(C)(C)C(C)(C)O2)c1.Cc1cc2nc(-c3ccnc(Cl)c3)sc2c(-c2ccc(Cl)cc2)c1[C@@H](COC(=O)C(C)(C)C)OC(C)(C)C>>COc1cncc(-c2cc(-c3nc4cc(C)c([C@@H](COC(=O)C(C)(C)C)OC(C)(C)C)c(-c5ccc(Cl)cc5)c4s3)ccn2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20040023938A1,CCc1ccc(S(=O)(=O)Nc2ccc(Cl)cc2)cc1.O=[N+]([O-])O>>CCc1ccc(S(=O)(=O)Nc2ccc(Cl)cc2[N+](=O)[O-])cc1,,CC(=O)O,,O,,test
US06262045B1,CNC.Cn1c2ccccc2c2c(CC(=O)O)nn(-c3ccccc3)c(=O)c21>>CN(C)C(=O)Cc1nn(-c2ccccc2)c(=O)c2c1c1ccccc1n2C,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20090269301A1,CCOC(=O)C(=O)Cc1c[nH]c2ccccc12.Cc1ccc(C=O)cc1.NCCCn1ccnc1>>Cc1ccc(C2C(c3c[nH]c4ccccc34)=C(O)C(=O)N2CCCn2ccnc2)cc1,,CCO,,,,test
US20130109665A1,COC(=O)[C@@H](NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1)C(C)(C)C>>CC(C)(C)[C@H](NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1)C(=O)O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US06541506B1,COC(=O)CCCCCCCC=O.CS(C)=O.[Li]CCCC>>C#CC=CCCCCCCCC(=O)OC,,CS(C)=O,,,,test
US20020010181A1,Cc1cc(C)cc(N)c1.Clc1ncc(Cc2ccncc2)c2ccccc12>>Cc1cc(C)cc(Nc2ncc(Cc3ccncc3)c3ccccc23)c1,,CCO,,Cl,,test
US20030232889A1,CNC(=O)c1ccc(N)c(F)c1.O=C(O)c1ccc(F)c(F)c1F>>CNC(=O)c1ccc(Nc2c(C(=O)O)ccc(F)c2F)c(F)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04795486,COc1cn(C)c(=O)c(O)n1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1cn(C)c(=O)c(OS(=O)(=O)C(F)(F)F)n1,,ClCCl,,c1ccncc1,,test
US20100137362A1,CB1OB(C)OB(C)O1.COC(=O)c1cc(Cl)nc(Br)c1N>>COC(=O)c1cc(Cl)nc(C)c1N,,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US05032588,COc1ccc2cc(C(C)c3sc(-c4ccccc4)nc3O)ccc2c1.O=COCCl>>COC(=O)Oc1nc(-c2ccccc2)sc1C(C)c1ccc2cc(OC)ccc2c1,,c1ccncc1,,,,test
US20120238561A1,CC(=O)OC(C)=O.CNc1nc(N2C[C@H](C)O[C@H](C)C2)sc1-c1cc(C)nc(C)c1>>CC(=O)NCc1nc(N2C[C@H](C)O[C@H](C)C2)sc1-c1cc(C)nc(C)c1,,ClCCl,,CCN(CC)CC,,test
US20120101138A1,CC(=O)c1ccc(COC2CCCCO2)o1>>CC(=O)c1ccc(CO)o1,,CO,,,,test
US20120328661A1,CCOC(=O)CC(=O)OCC.CCc1c(OC)ccc(C=O)c1O>>CCOC(=O)c1cc2ccc(OC)c(CC)c2oc1=O,,CCO,,C1CCNCC1,,test
US05231183,CNC/C=C/C#CC(C)(C)C.Cl.ClCc1cccc2ccccc12>>CN(C/C=C/C#CC(C)(C)C)Cc1cccc2ccccc12.Cl,,CS(C)=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20100160335A1,COCNC(=O)c1ccc(OC)c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n1.C[Mg]Br>>COc1ccc(C(C)=O)nc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,C1CCOC1,,[Cl-].[NH4+],,test
US20150353533A1,CCOC(=O)c1cc(C)n(C(C)=O)n1.O=C1CCC(=O)N1Br>>CCOC(=O)c1cc(CBr)n(C(C)=O)n1,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20130172339A1,COC(=O)c1cccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)c1>>Cc1c(S(=O)(=O)Nc2cccc(C(=O)O)c2)sc2ccc(Cl)cc12,,CO,,[K+].[OH-],,test
US20080269293A1,Nc1ccccc1Oc1ccnn1-c1ccccc1.O=C=Nc1ccc(OC(F)(F)F)cc1>>O=C(Nc1ccc(OC(F)(F)F)cc1)Nc1ccccc1Oc1ccnn1-c1ccccc1,,C1CCOC1,,CCN(CC)CC,,test
US03979430,CC(C(N)=O)c1ccc2c(c1)C=Cc1ccccc1C21OCCO1>>CC(C(N)=O)c1ccc2c(=O)c3ccccc3ccc2c1,,O,,CO,,test
US20070100131A1,Nc1ccccc1N.O=C(O)c1cc(O)cc(O)c1>>Oc1cc(O)cc(-c2nc3ccccc3[nH]2)c1,,Cl,,[Na+].[OH-],,test
US20110306587A1,O=C(O)c1nc2ccccc2[nH]1.c1ccc(-c2cccnc2C2CNC2)cc1>>O=C(c1nc2ccccc2[nH]1)N1CC(c2ncccc2-c2ccccc2)C1,,CN(C)C=O,O,Cl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150175582A1,CCOC(=O)c1cnc(Nc2ccc(N3CCCCC3)cc2)[nH]c1=O>>O=C(O)c1cnc(Nc2ccc(N3CCCCC3)cc2)[nH]c1=O,,CO,,[Na+].[OH-],,test
US20140121200A1,C=O.c1cnc2c(NCC3CCCNC3)nc(-c3ccc(N4CCOCC4)cc3)cc2n1>>CN1CCCC(CNc2nc(-c3ccc(N4CCOCC4)cc3)cc3nccnc23)C1,,C1CCOC1,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100273764A1,CC(C)OB(OC(C)C)OC(C)C.CSc1ccc(C(C)c2ccc(F)nc2)cc1>>CSc1ccc(C(C)c2cnc(F)c(B(O)O)c2)cc1,,C1CCOC1,O,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US20080032972A1,Fc1ccc(F)c(CC2CCNc3ncccc32)c1.O=C1CCC(=O)N1Br>>Fc1ccc(F)c(CC2CCNc3ncc(Br)cc32)c1,,CC(=O)O,ClCCl,,,test
US20130059834A1,CC(NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(CCN4CCOCC4)c4cc(F)ccc34)nc12)c1ccncc1>>CC(NC(=O)c1c[nH]c2ncc(-c3nn(CCN4CCOCC4)c4cc(F)ccc34)nc12)c1ccncc1,,ClCCl,,NCCN,O=C(O)C(F)(F)F,test
US04935491,O=C(O)c1ccccn1.O=[N+]([O-])c1ccc(O)cc1>>O=C(Oc1ccc([N+](=O)[O-])cc1)c1ccccn1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04294960,CC(C)CBr.CCOC(=O)C(=NO)C(C)=O>>CCOC(=O)C(=NOCC(C)C)C(C)=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120068170A1,CC(C)(C)c1ccc(-c2nc(Cl)nc(-c3ccc(C(C)(C)C)cc3)n2)cc1.CC1(C)c2ccccc2-c2cc3c(cc21)[nH]c1ccccc13>>CC(C)(C)c1ccc(-c2nc(-c3ccc(C(C)(C)C)cc3)nc(-n3c4ccccc4c4cc5c(cc43)C(C)(C)c3ccccc3-5)n2)cc1,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US06194461B1,CC(C)(COCc1ccccc1)[N+](=O)[O-].O=Cc1ccc(F)cc1F>>CC(C)(COCc1ccccc1)[N+]([O-])=Cc1ccc(F)cc1F,[Zn],CCO,,CC(=O)O,,test
US20120178746A1,C1CCOC1.COC(=O)C[C@]1(c2ccc(F)cc2)CCN([C@@H](C)c2ccc(-c3ccc(=O)n(C)c3)cc2)C(=O)O1.C[Mg]Br>>C[C@@H](c1ccc(Br)cc1)N1CC[C@](CC2(O)CC2)(c2ccc(F)cc2)OC1=O,CC(C)O[Ti](OC(C)C)(OC(C)C)OC(C)C,,,,,test
US20130131042A1,COC(=O)c1ccc(N2CC3(CCN(C(=O)OC(C)(C)C)CC3)OC2=O)cc1.Cl>>COC(=O)c1ccc(N2CC3(CCNCC3)OC2=O)cc1.Cl,,C1COCCO1,,,,test
US20080188531A1,CC(=O)Nc1nc(C)c(-c2csc(C(=O)Cl)n2)s1.OC1CCNC1>>CC(=O)Nc1nc(C)c(-c2csc(C(=O)N3CCC(O)C3)n2)s1,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US20080004271A1,N#Cc1c(O)ncnc1-c1cccc([N+](=O)[O-])c1.O=P(Cl)(Cl)Cl>>N#Cc1c(Cl)ncnc1-c1cccc([N+](=O)[O-])c1,,C1COCCO1,,,,test
US20120184553A1,CN(C)S(=O)(=O)c1ccc(OCc2ccccc2)c(C(=O)O)c1.Nc1cccnc1>>CN(C)S(=O)(=O)c1ccc(OCc2ccccc2)c(C(=O)Nc2cccnc2)c1,,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US05322961,CC(C)(C)OC(=O)NOCc1ccccc1.N#CCCCCN(OCc1ccccc1)C(=O)CCCCCl>>CC(C)(C)OC(=O)N(CCCCC(=O)N(CCCCC#N)OCc1ccccc1)OCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US04011340,C1N2CN3CN1CN(C2)C3.CC(C)(C)C(=O)c1ccc(CBr)cc1>>CC(C)(C)C(=O)c1ccc(C[N+]23CN4CN(CN(C4)C2)C3)cc1.[Br-],,ClC(Cl)Cl,,,,test
US20100113502A1,C=CCBr.O=[N+]([O-])c1ccc2c(c1)C1CN(C3CCOCC3)CCC1N2>>C=CCN1c2ccc([N+](=O)[O-])cc2C2CN(C3CCOCC3)CCC21,,CN(C)C=O,,[H-].[Na+],,test
US20100063025A1,COc1ccc(Cn2ccc3cc(F)c(C)cc3c2=O)cc1.OC1CCCNCC1>>COc1ccc(Cn2ccc3cc(OC4CCCNCC4)c(C)cc3c2=O)cc1,,CC(=O)N(C)C,,O,[H-].[Na+],test
US20130131039A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.Clc1nc(-c2ccc(N3CCOCC3)cc2)cc2nccn12>>c1cn2c(-c3cn[nH]c3)nc(-c3ccc(N4CCOCC4)cc3)cc2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US03937840,CC(C)Br.Cc1ccccc1C(=O)Nc1cccc(O)c1>>Cc1ccccc1C(=O)Nc1cccc(OC(C)C)c1,,[K+],[OH-],CCO,,test
US20020052378A1,CCOC(=O)C(CC(C)C)c1csc(-c2ccccc2)n1>>CC(C)CC(C(=O)O)c1csc(-c2ccccc2)n1,,CO,,[Na+].[OH-],,test
US20050244332A1,BrBr.COc1cc(CC(=O)c2ccc3c(c2)CCC(C)(C)O3)cc(OC)c1OC>>COc1cc(C(Br)C(=O)c2ccc3c(c2)CCC(C)(C)O3)cc(OC)c1OC,,ClC(Cl)(Cl)Cl,,,,test
US20160016940A1,CC1(C)COB(c2cc3cc[nH]c3cc2Cl)OC1.CN(C)C=O.O=C1COC(c2ccc(Br)cc2)CN1>>O=Cc1c[nH]c2cc(Cl)c(-c3ccc(C4CNC(=O)CO4)cc3)cc12,,C1COCCO1,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20020183337A1,CC(C)(C)[Si](C)(C)Cl.CC(C)Cn1c(=O)n(C)c(=O)c2cc(C(O)c3cccc4ccccc34)sc21>>CC(C)Cn1c(=O)n(C)c(=O)c2cc(C(O[Si](C)(C)C(C)(C)C)c3cccc4ccccc34)sc21,,CN(C)C=O,,c1c[nH]cn1,,test
US06350749B1,Cc1c[n+]([O-])nc2c1C(=O)CC(c1ccccc1Cl)C2.Cl.N=C(N)NN>>Cc1c[n+]([O-])nc2c1C(=NNC(=N)N)CC(c1ccccc1Cl)C2.Cl,,CCO,,Cl,,test
US04126624,CC(=O)c1occc1O.ClP(Cl)(Cl)(Cl)Cl>>CC(=O)c1occc1Cl,,ClCCl,,O,,test
US05318966,CN(C)C(=O)Cl.Cl.O=C1c2ccccc2C(=O)N1CCCCCCN1CC[C@@H]2c3cccc(O)c3CC[C@@H]21>>CN(C)C(=O)Oc1cccc2c1CC[C@H]1[C@@H]2CCN1CCCCCCN1C(=O)c2ccccc2C1=O.Cl,CN(C)c1ccncc1,Cc1ccccc1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20120329791A1,CC(=O)OC(C)(C)C(=O)Cl.CC1(C)OB(c2cccc(N)c2)OC1(C)C>>CC(=O)OC(C)(C)C(=O)Nc1cccc(B2OC(C)(C)C(C)(C)O2)c1,,CC(=O)N(C)C,CCOC(C)=O,CCN(CC)CC,,test
US05436260,CCCCc1ncc(/C=C2\NC(=O)NC2=O)n1Cc1ccc(C(=O)OC)cc1.C[Si](C)(C)CCOCCl>>CCCCc1ncc(/C=C2\NC(=O)N(COCC[Si](C)(C)C)C2=O)n1Cc1ccc(C(=O)OC)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20060052392A1,CCOC(=O)CBr.Cc1cc2c(cc1C)C(O)N(c1cccc(F)c1)C2=O>>CCOC(=O)COC1c2cc(C)c(C)cc2C(=O)N1c1cccc(F)c1,,C1CCOC1,,[H-].[Na+],,test
US04997847,NC/C=C\CCCC(=O)O.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=C(O)CCC/C=C\CNS(=O)(=O)c1ccc(Cl)cc1,,ClC(Cl)Cl,O,[Na+].[OH-],,test
US20150284409A1,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)O.COc1ccc2c(Cl)nccc2c1>>COc1cnc(O[C@@H]2C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C2)c2ccccc12,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20100292235A1,CN(C)CCN.O=c1occc2c([N+](=O)[O-])cccc12>>CN(C)CCn1ccc2c([N+](=O)[O-])cccc2c1=O,,CO,,,,test
US20090264406A1,Cn1cc(-c2ccc3ncc(C(O)c4ccc5nc(NC(=O)C(F)(F)F)cn5c4)n3n2)cn1>>Cn1cc(-c2ccc3ncc(C(O)c4ccc5nc(N)cn5c4)n3n2)cn1,,C1CCOC1,CO,O,O=C([O-])[O-].[K+].[K+],test
US20150080369A1,Cc1ccc(NCC(C)C)c(C)c1.O=S(=O)(Cl)c1ccc(OCc2ccccc2)cc1>>Cc1ccc(N(CC(C)C)S(=O)(=O)c2ccc(OCc3ccccc3)cc2)c(C)c1,,c1ccncc1,,,,test
US20090149439A1,Cc1cc(C(=O)NCCO)ncc1C(Sc1ccc(F)cc1)c1cc(F)ccc1F.O=C(OO)c1cccc(Cl)c1>>Cc1cc(C(=O)NCCO)ncc1C(c1cc(F)ccc1F)S(=O)c1ccc(F)cc1,,ClCCl,,,,test
US20100137317A1,CN1C(=O)C(Br)=C(Br)C1=O.O=C1CCNCC1>>CN1C(=O)C(Br)=C(N2CCC(=O)CC2)C1=O,,O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100087471A1,Cc1ccc(NN=C(c2ccccc2)c2ccccc2)cc1.O=C(Cl)Cc1ccc(Cl)cc1>>Cc1ccc(N(N=C(c2ccccc2)c2ccccc2)C(=O)Cc2ccc(Cl)cc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20150353553A1,COC(=O)c1nc(N[C@H](C)C2CCC2)c2c(n1)nc(C1=C(c3ccccc3)CCCC1)n2Cc1ccc(C(F)(F)F)cc1>>COC(=O)c1nc(N[C@H](C)C2CCC2)c2c(n1)nc(C1CCCCC1c1ccccc1)n2Cc1ccc(C(F)(F)F)cc1,[Pd],CO,,,,test
US20070066624A1,Cc1nc(Br)ccc1C=O.N#Cc1ccc(O)cc1Cl>>Cc1nc(Oc2ccc(C#N)c(Cl)c2)ccc1C=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120004203A1,CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(N(CC#N)C(=O)OCc3ccccc3)nc2N1c1cccc(C(F)(F)F)c1>>CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(NCC#N)nc2N1c1cccc(C(F)(F)F)c1,[Pd],CO,,,,test
US05631280,CC(C)(C)OC(=O)N[C@H](C=O)CSC(c1ccccc1)(c1ccccc1)c1ccccc1.Cc1cccc(NC(=O)c2cccc(N)c2)c1C>>Cc1cccc(NC(=O)c2cccc(NC[C@H](CSC(c3ccccc3)(c3ccccc3)c3ccccc3)NC(=O)OC(C)(C)C)c2)c1C,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05047411,CCNc1nc2ccc(C=Cc3nccn3Cc3ccccc3)cc2o1>>CCNc1nc2ccc(CCc3ncc[nH]3)cc2o1,[Pd],CO,,Cl,,test
US04840971,CCOC(=O)C1OC1(c1ccc2c(c1)OCO2)C(F)(F)F>>O=CC(c1ccc2c(c1)OCO2)C(F)(F)F,,CCO,O,[K+].[OH-],,test
US20100137281A1,CCc1cc2c(=O)[nH]c(=O)n(Cc3c(F)cc(-c4ccccc4C#N)cc3F)c2s1.COc1ccc(C(=O)CBr)cc1>>CCc1cc2c(=O)n(CC(=O)c3ccc(OC)cc3)c(=O)n(Cc3c(F)cc(-c4ccccc4C#N)cc3F)c2s1,,CCOC(C)=O,,CN(C)C=O,[H-].[Na+],test
US20040254215A1,O=C(O)CNC(=O)c1nc(Sc2ccccc2)c2ccccc2c1O.O=C(OO)c1cccc(Cl)c1>>O=C(O)CNC(=O)c1nc(S(=O)c2ccccc2)c2ccccc2c1O,,ClCCl,,,,test
US20100152160A1,CCOC(=O)C1(Cc2ccc(F)cc2)CCN(C(=O)C2CN(C(=O)OC(C)(C)C)c3cc(Cl)c(O)cc3O2)CC1.CI>>CCOC(=O)C1(Cc2ccc(F)cc2)CCN(C(=O)C2CN(C(=O)OC(C)(C)C)c3cc(Cl)c(OC)cc3O2)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150045408A1,CCCC1(C(=O)c2ccc(Cl)c(Cl)c2)CCNC1.O=C(O)[C@@H](O)[C@H](O)C(=O)O>>CCC[C@]1(C(=O)c2ccc(Cl)c(Cl)c2)CCNC1.O=C(O)[C@@H](O)[C@H](O)C(=O)O,,CO,O,Cl,[Na+].[OH-],test
US20100093730A1,Fc1ccc(C(c2ccc(F)cc2)N2CCNCC2)cc1.O=C(O)CN1CCC(c2ccccc2)(c2ccccc2)C1=O>>O=C(CN1CCC(c2ccccc2)(c2ccccc2)C1=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20050054696A1,NNC(=O)c1cc2cc(Cl)ccc2[nH]1.O=C(Cl)c1ccccc1>>O=C(NNC(=O)c1cc2cc(Cl)ccc2[nH]1)c1ccccc1,,C1CCOC1,,CCN(CC)CC,CCOC(C)=O,test
US06900243B2,CCCCC(O)CCN(C)C(=O)OC(C)(C)C.Oc1cc(Cl)ccc1Cl>>CCCCC(CCN(C)C(=O)OC(C)(C)C)Oc1cc(Cl)ccc1Cl,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20120157487A1,O=S(Cl)Cl.O=[N+]([O-])c1cc(CO)n[nH]1>>O=[N+]([O-])c1cc(CCl)n[nH]1,,ClCCl,,,,test
US20140051679A1,C[C@@H](N)C1CCCCC1.O=C(O)c1ccc2[nH]ncc2c1>>C[C@@H](NC(=O)c1ccc2[nH]ncc2c1)C1CCCCC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20120077760A1,C[C@H](O)C(=O)O.N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F>>C[C@H](O)C(=O)[O-].N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F,,CC(C)O,CO,,,test
US04886877,O=C(Cl)c1ccccc1.O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1F>>O=C(c1ccccc1)n1c(=O)c(F)cn([C@H]2C[C@H](O)[C@@H](CO)O2)c1=O,,CC(=O)N(C)C,,CCN(CC)CC,,test
US20130210796A1,CC(C)(C)N(C(=O)[O-])c1ccc(Br)c(OC(F)(F)F)c1.N#C[Cu]>>N#Cc1ccc(N)cc1OC(F)(F)F,,CN(C)C=O,O,Cl,,test
US20130053409A1,COc1cc(N2CC[C@H](N(C)C)C2)c([N+](=O)[O-])cc1Nc1nccc(-c2cn(C)c3ccccc23)n1>>COc1cc(N2CC[C@H](N(C)C)C2)c(N)cc1Nc1nccc(-c2cn(C)c3ccccc23)n1,[Fe],O,,CCO,[Cl-].[NH4+],test
US20120115864A1,CCCn1cnc2nc(-c3ccc(O)cc3)n(COCC[Si](C)(C)C)c2c1=O>>CCCn1cnc2nc(-c3ccc(O)cc3)[nH]c2c1=O,,CCO,,Cl,,test
US20130261159A1,CI.OCc1coc(CCl)n1>>COCc1coc(CCl)n1,,ClCCl,,N#N,,test
US20120004187A1,CC#CC(CC(=O)OC)c1ccc(OCC2(CO)CC2)cc1.Oc1ccccc1>>CC#CC(CC(=O)OC)c1ccc(OCC2(COc3ccccc3)CC2)cc1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20010056100A1,O=C(O)c1ccc(CCl)cc1>>OCc1ccc(CCl)cc1,,C1CCOC1,,B,,test
US04173634,O=C1C(=Cc2ccc(Cl)cc2)Cc2ccccc21.OO>>O=C1C(=Cc2ccc(Cl)cc2)CC23OC2C=CC=C13,,CO,,[Na+].[OH-],,test
US05922771,COc1ccc2c(c1)/C(=C/CN)CC2.O=C(O)C(F)(F)F>>COc1ccc2c(c1)C(CCNC(=O)C(F)(F)F)=CC2,,ClCCl,O,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US20110275797A1,CC(=O)OC(C)=O.O=C(O)c1cc(-c2cccnc2)ccc1O>>CC(=O)Oc1ccc(-c2cccnc2)cc1C(=O)O,,c1ccncc1,,ClCCl,,test
US20110172227A1,C=CCN.O=C(Cl)c1ccccc1>>C=CCNC(=O)c1ccccc1,,ClCCl,,,,test
US20150315141A1,CC(C)c1cc(C(C)C)c(S(=O)(=O)N=[N+]=[N-])c(C(C)C)c1.COC(=O)C1CCc2cccnc21>>COC(=O)C1(N=[N+]=[N-])CCc2cccnc21,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04254267,NN.O=C(O)C=CC(=O)c1ccco1>>O=C(O)C1CC(c2ccco2)=NN1,,CO,,[K+].[OH-],,test
US04051173,CC(C)(Oc1ccc(COc2ccc(Cl)cc2)cc1)C(=O)O>>CC(C)(CO)Oc1ccc(COc2ccc(Cl)cc2)cc1,,C1CCOC1,O,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20130029970A1,Cc1cc2ccsc2[nH]1.ClCCN1CCOCC1>>Cc1cc2ccsc2n1CCN1CCOCC1,O,CS(C)=O,O,Cl,[K+].[OH-],test
US20070049534A1,COc1ccc(O)c(C(C)C)c1.Cc1ccc(S(=O)(=O)OCC#N)cc1>>COc1ccc(OCC#N)c(C(C)C)c1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030216394A1,CC(C)(C)c1nc(CCl)co1.[C-]#N>>CC(C)(C)c1nc(CC#N)co1,,CS(C)=O,,[Na+].[OH-],,test
US04258049,CC(=O)OC(C)=O.O=[N+]([O-])c1c(SCc2ccccc2)ccc2c1CNCC2>>CC(=O)N1CCc2ccc(SCc3ccccc3)c([N+](=O)[O-])c2C1,,CC(=O)O,,Cl,CC(=O)[O-].[Na+],test
US05840917,BrCc1ccccc1.O=Cc1ccsc1C(=O)O>>O=Cc1ccsc1C(=O)OCc1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05177100,N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1SC(F)(F)F.c1ccc(SSc2ccccc2)cc1>>N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(Sc2ccccc2)c1SC(F)(F)F,,ClC(Cl)Cl,,CC(C)(C)ON=O,,test
US20050026922A1,CNC1CCCCC1.ClCc1ccc(Cl)nc1>>CN(Cc1ccc(Cl)nc1)C1CCCCC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05574042,CC(=O)N(C)c1cccc(Cl)c1COc1cccn2c(Br)c(C)nc12>>CCN(C)c1cccc(Cl)c1COc1cccn2c(Br)c(C)nc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120157454A1,CC(C)(C)OC(=O)NCCCCCCNCC(=O)Nc1ccc2[nH]c(=O)c3ccccc3c2c1.O=C(O)C(F)(F)F>>NCCCCCCNCC(=O)Nc1ccc2[nH]c(=O)c3ccccc3c2c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20050256142A1,CC[C@H](C=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1.CC[Mg]Br>>CCC(O)[C@H](CC)NC(c1ccccc1)(c1ccccc1)c1ccccc1,,CCOCC,,O,,test
US05840758,Cc1ccc(Cl)c(Nc2ccccc2C=O)c1Cl.NOCC(=O)O.NOCC(=O)O.c1ccncc1>>Cc1ccc(Cl)c(Nc2ccccc2-c2ccccc2C=NOCC(=O)O)c1Cl,,CCO,,Cl,,test
US20090270436A1,CCI.COC(=O)c1cc(O)c(Br)c(OC)c1>>CCOc1cc(C(=O)OC)cc(OC)c1Br,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US06800778B1,CCOC(=O)C1(C(=O)c2ccccc2Cl)CCCC1>>CCOC(=O)C1(C(O)c2ccccc2Cl)CCCC1,,CO,O,,,test
US20140309266A1,N#Cc1cc(I)c(I)s1.O=Cc1ccc(Cl)cc1>>N#Cc1cc(I)c(C(O)c2ccc(Cl)cc2)s1,,C1CCOC1,,CC(C)[Mg]Cl,[Cl-].[NH4+],test
US07094798B1,COc1ccc(CN)c(OC)c1.COc1ccc2[nH]c3c(c2c1)C1C(=O)OC(=O)C1C(c1ccccc1Cl)C3>>COc1ccc(CN2C(=O)c3c(-c4ccccc4Cl)cc4[nH]c5ccc(OC)cc5c4c3C2=O)c(OC)c1,,CC(=O)O,,,,test
US20160038504A1,COC[C@@H](C)Oc1ncc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)cnc2C)cc1N1CCOCC1>>Cc1ncc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cnc(O[C@H](C)CO)c(N2CCOCC2)c1,,ClCCl,,BrB(Br)Br,,test
US20120094972A1,CC1(C)CNc2cc(Br)cnc21.Cc1c(-c2ccccc2S(C)(=O)=O)nc2cc(F)ccc2c1Cl>>Cc1c(-c2ccccc2S(C)(=O)=O)nc2cc(F)ccc2c1N1CC(C)(C)c2ncc(Br)cc21,,CN1CCCC1=O,,C1COCCO1,Cl,test
US20020055631A1,CCCCn1c(=O)[nH]c2cc(-c3ccc(C(=O)NS(=O)(=O)c4ccc(N[C@H](CO[Si](C)(C)C(C)(C)C)CSc5ccccc5)c([N+](=O)[O-])c4)cc3)ccc21>>CCCCn1c(=O)[nH]c2cc(-c3ccc(C(=O)NS(=O)(=O)c4ccc(N[C@H](CO)CSc5ccccc5)c([N+](=O)[O-])c4)cc3)ccc21,,C1CCOC1,,Cl,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100029634A1,CC(C)(C)OC(=O)NCCCCNC1CCCc2cccnc21.O=Cc1cccc2cc[nH]c12>>CC(C)(C)OC(=O)NCCCCN(Cc1cccc2cc[nH]c12)C1CCCc2cccnc21,CC(=O)O,ClCCCl,,O=C([O-])O.[Na+],,test
US05663366,Cn1nc(Br)c([N+](=O)[O-])c1NCCO>>Cn1ncc(N)c1NCCO,,O,,O=S(=O)(O)O,,test
US20100093731A1,COc1nc(Cl)nc(Nc2ccc(-n3cnc(C)c3)c(OC)c2)n1.O=C(O)CC1CCNCC1>>COc1nc(Nc2ccc(-n3cnc(C)c3)c(OC)c2)nc(N2CCC(CC(=O)O)CC2)n1,,CO,,CCN(CC)CC,Cl,test
US07091199B1,BrCCCOc1cccc(-c2noc3ccsc23)c1.c1ccc2c(c1)CCNC2>>c1cc(OCCCN2CCc3ccccc3C2)cc(-c2noc3ccsc23)c1,,ClCCl,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20090227602A1,Cc1ccc(S(=O)O)cc1.NC(=O)c1ccccc1.O=Cc1ccc(F)cc1>>Cc1ccc(S(=O)(=O)C(NC(=O)c2ccccc2)c2ccc(F)cc2)cc1,,CC#N,Cc1ccccc1,C[Si](C)(C)Cl,,test
US20110105463A1,CCOC(=O)C1CCOc2cc(Oc3ccc(C(=O)NCCc4ccc(-c5ccccc5)cc4)cc3)c(C#N)cc21.Cl>>O=C(NCCc1ccc(-c2ccccc2)cc1)c1ccc(Oc2cc3c(cc2Cl)C(C(=O)O)CCO3)cc1,,C1CCOC1,,O,[Li]O,test
US20080132496A1,CCOC(=O)c1nn(-c2ccc(C(=O)O)cc2C(F)(F)F)c2c1CCC2.NCCc1nc2cc(Cl)ccc2[nH]1>>CCOC(=O)c1nn(-c2ccc(C(=O)NC(C)c3nc4cc(Cl)ccc4[nH]3)cc2C(F)(F)F)c2c1CCC2,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US04465851,Cl.N=C(N)NC[C@@H]1CC[C@@H](C(=O)O)CC1.O=c1c(O)c(-c2ccccc2)oc2ccccc12>>Cl.N=C(N)NC[C@@H]1CC[C@@H](C(=O)Oc2cccc(-c3cc(=O)c4ccccc4o3)c2)CC1,,c1ccncc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20060003970A1,CC(=O)OCN(C)N=Nc1ccc2ncnc(Nc3cccc(Cl)c3)c2c1>>COCN(C)N=Nc1ccc2ncnc(Nc3cccc(Cl)c3)c2c1,,CO,,,,test
US20070203159A1,CCCCO.COc1ccc(Cn2cnc3c(-c4ccco4)nc([N+](=O)[O-])nc32)cc1>>CCCCOc1nc(-c2ccco2)c2ncn(Cc3ccc(OC)cc3)c2n1,,CCCCO,,[F-].[K+],,test
US20090227627A1,O=[N+]([O-])c1cc(F)c(F)cc1CO.Sc1cccc(C2OCCCO2)c1>>O=[N+]([O-])c1cc(F)c(Sc2cccc(C3OCCCO3)c2)cc1CO,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20030018032A1,Nc1cnccn1.O=Cc1ccncc1.[C-]#[N+]C(C)(C)CC(C)(C)C>>CC(C)(C)CC(C)(C)Nc1c(-c2ccncc2)nc2cnccn12,,[O-][Cl+3]([O-])([O-])O,,,,test
US04480100,Nc1ccccc1C(=O)c1cccc(F)c1.O=[N+]([O-])c1cccnc1Cl>>O=C(c1cccc(F)c1)c1ccccc1Nc1ncccc1[N+](=O)[O-],,CCOC(C)=O,,Cc1ccccc1,,test
US20050176701A1,CCOC(=O)CC(O)(CCNC(=O)CCc1ccco1)C1CCCC1>>O=C(O)CC(O)(CCNC(=O)CCc1ccco1)C1CCCC1,,ClCCl,,[Na+].[OH-],,test
US05840732,CCCC=C1SC(=O)N(CCCCSc2cccc3ncc(Br)n23)C1=O.Cl>>CCCC=C1SC(=O)N(CCCCSc2cccc3ncc(Br)n23)C1=O.Cl,,CO,,,,test
US20040019069A1,CC(C)(C)OC(=O)n1cc(CO)c2ccccc21.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)n1cc(COS(C)(=O)=O)c2ccccc21,,ClCCl,,CCN(CC)CC,,test
US20120022080A1,CC(C)(C)O.O=C(O)c1ccc(C23CC4CC(CC(C4)C2)C3)cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)Nc1ccc(C23CC4CC(CC(C4)C2)C3)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20010003121A1,Nc1cccc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1Cl.O=CCCl>>O=C(NCC12CC3CC(CC(C3)C1)C2)c1cccc(NCCCl)c1Cl,,CO,O,Cl,[BH3-]C#N.[Na+],test
US20120065233A1,CC(C)N1C(=O)c2cc(N)c([N+](=O)[O-])cc2C1=O.COc1nccc(Cl)c1C=O>>COc1nccc(Cl)c1-c1nc2cc3c(cc2[nH]1)C(=O)N(C(C)C)C3=O,,CO,,CC(=O)O,,test
US20040092737A1,CC(=O)O.CNS(=O)(=O)CCC1CCNCC1>>CC(=O)O.CNS(=O)(=O)CCC1CCNCC1,O=[Pt],,,,,test
US20090088457A1,Brc1cnc(Br)s1.O[C@H]1CCNC1>>O[C@H]1CCN(c2nccs2)C1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20140045862A1,CCn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)N(C(=O)OC(C)(C)C)c2cscn2)cc1Cl>>CCn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130040977A1,N#Cc1ccc2[nH]c3ccccc3c2c1.c1ccc(OCC2CO2)cc1>>N#Cc1ccc2c(c1)c1ccccc1n2CC(O)COc1ccccc1,,C1CCOC1,,O,[Li]CCCC,test
US20010020089A1,CCNC(=O)[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(C(=O)NCCN4CCCCC4)nc32)[C@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1>>CCNC(=O)[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(C(=O)NCCN4CCCCC4)nc32)[C@H](O)[C@@H]1O,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20090203677A1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CN(Cc1ccc(C)c(-c2cccc(C=O)c2)c1)C(=O)C1(C(N)=O)CC1.C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CN(Cc1ccc(C)c(-c2cccc(CN3CCN[C@@H](C)C3)c2)c1)C(=O)C1(C(N)=O)CC1,,ClCCl,O=C(O)C(F)(F)F,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20150337004A1,COc1ccc(-c2cnc([C@@H]3CCCN3C(=O)[C@]34CC[C@@H](C(C)C)[C@@H]3[C@H]3CC[C@H]5[C@@](C)(CC[C@H]6C(C)(C)[C@@H](OC(=O)[C@H]7C[C@@H](C(=O)OCc8ccccc8)C7(C)C)CC[C@@]65C)[C@]3(C)CC4)[nH]2)cc1>>COc1ccc(-c2cnc([C@@H]3CCCN3C(=O)[C@]34CC[C@@H](C(C)C)[C@@H]3[C@H]3CC[C@H]5[C@@](C)(CC[C@H]6C(C)(C)[C@@H](OC(=O)[C@H]7C[C@@H](C(=O)O)C7(C)C)CC[C@@]65C)[C@]3(C)CC4)[nH]2)cc1,[Pd],CCOC(C)=O,CO,,,test
US20150191452A1,CCN(CC)S(F)(F)F.Cc1ccc(CN2CCC(N3CC[C@@H](c4ccc(O)cc4)[C@H](O)C3)C2=O)cc1F>>Cc1ccc(CN2CCC(N3CC[C@@H](c4ccc(O)cc4)[C@H](F)C3)C2=O)cc1F,,ClCCl,,,,test
US20090264445A1,CCI.C[C@@H](O)C[C@H]1COC(C)(C)N1C(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)O)cc1>>CCO[C@H](C)C[C@H](NC(=O)OC(C)(C)C)C(=O)O,,C1CCOC1,CO,[H-].[Na+],,test
US06380387B1,COC(=O)[C@H](Cc1ccc(-c2cn(C)c(=O)n(C)c2=O)c(C)c1)NC(=O)c1c(Cl)cccc1Cl>>Cc1cc(C[C@H](NC(=O)c2c(Cl)cccc2Cl)C(=O)O)ccc1-c1cn(C)c(=O)n(C)c1=O,,CCO,,[Na+].[OH-],,test
US20020198213A1,CN1C(=O)CC(c2c[nH]c3ccccc23)C1=O>>CN1CCC(c2c[nH]c3ccccc23)C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05786367,C=CCOc1ccc2c(c1)CCC(=O)N2.COc1ccc(Br)cc1>>C=CCOc1ccc2c(c1)CCC(=O)N2c1ccc(OC)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04160032,CC1C(=S)Nc2ccc(C(F)(F)F)cc21.CO>>O=C1Cc2cc(C(F)(F)F)ccc2N1,[Ni],ClCCl,,,,test
US20160137649A1,CC(C)(C)OC(=O)N1CC2CN(Cc3cccc(Cl)c3N3CCC(O)CC3)CC2C1>>CC(C)(C)OC(=O)N1CC2CN(Cc3cccc(Cl)c3N3CCC(=O)CC3)CC2C1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20160172678A1,C=CC(=O)OCCCC.C=COC(C)=O>>C=CC(=O)OCCCC.C=COC(C)=O,,CO,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US04163784,COC(=O)c1ccncc1.NC(N)=O>>NC(=O)NC(=O)c1ccncc1,,N,,[Na],,test
US20160046614A1,CCCn1cc(Br)cn1.Fc1c(Cl)ccc2cc[nH]c12>>CCCn1cc(-n2ccc3ccc(Cl)c(F)c32)cn1,[Cu]I,CCOC(C)=O,Cc1ccccc1,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20050020623A1,CC(C)(C)OC(=O)N1CCC(Nc2cccc3c(Cl)nccc23)CC1.O=C(O)C(F)(F)F>>Clc1nccc2c(NC3CCNCC3)cccc12.O=C(O)C(F)(F)F,,ClCCl,,,,test
US03973022,CC(C(=O)O)(C(=O)O)c1ccc2nc(-c3ccc(Cl)cc3)ccc2c1>>CC(C(=O)O)c1ccc2nc(-c3ccc(Cl)cc3)ccc2c1,,CCOC(C)=O,,,,test
US20090137580A1,CC(C)(C)n1cc(N)cn1.Cn1ccc2ncnc(Oc3ccc(N)c(Cl)c3)c21.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cnn(C(C)(C)C)c4)c(Cl)c3)c21,,ClCCl,,CCN(CC)CC,,test
US20100076026A1,COC(=O)c1ccc(N=C=O)c(Cl)c1.Clc1ccc(-n2nc3ccccc3c2NC2CCCCC2)cc1>>COC(=O)c1ccc(NC(=O)N(c2c3ccccc3nn2-c2ccc(Cl)cc2)C2CCCCC2)c(Cl)c1,,ClCCCl,,CCN(CC)CC,,test
US05407599,Fc1cccc(OCCCCCCC2CC2)c1F.O=C=O>>O=C(O)c1ccc(OCCCCCCC2CC2)c(F)c1F,,C1CCOC1,,[Li]CCCC,,test
US20050143421A1,CC(=O)NC[C@H]1CN(c2cc(F)c(N3CCC(=O)CC3)c(F)c2)C(=O)O1.OCCO>>CC(=O)NC[C@H]1CN(c2cc(F)c(N3CCC4(CC3)OCCO4)c(F)c2)C(=O)O1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20160039825A1,C1CNCCN1.CN(C)C=O.O=C(OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCCn2nc(CBr)cc2C1>>CN1CCN(Cc2cc3n(n2)CCCN(C(=O)OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C3)CC1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20020173646A1,COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1O.ClCCl.O=C1CCCN1CCO>>COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCN1CCCC1=O.Cl,,CCOCC,ClCCl,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US06069141,CC(=O)NCC1CC(c2ccc(N3CCSCC3)c(F)c2)=NO1.O>>CC(=O)NCC1CC(c2ccc(N3CCS(=O)CC3)c(F)c2)=NO1,,CO,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20120077806A1,CCCC(=O)c1ccc(OCCN(CC)CC)cc1.[NH4+]>>CCCC(N)c1ccc(OCCN(CC)CC)cc1,,CCOC(C)=O,CO,[BH3-]C#N.[Na+],,test
US20070238702A1,CC(C)CCCCBr.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CC(C)CCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-],,Cc1ccccc1,,,,test
US20130019348A1,CC(=O)CC(=O)Nc1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1.CC(C)c1ccccc1N=C=S>>C/C(O)=C(/C(=O)Nc1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1)C(=S)Nc1ccccc1C(C)C,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05849757,CCI.O=C(O)C1=CCC1>>CCOC(=O)C1=CCC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040242868A1,CC(C)CC(=O)O.Cc1ccc(N)cc1-c1ccc(C(=O)NCC2CC2)cc1>>Cc1ccc(NC(=O)CC(C)C)cc1-c1ccc(C(=O)NCC2CC2)cc1,,C1CCOC1,,,,test
US05532236,CCOC(=O)NNc1nc2ccc(-n3ccnc3)cc2n(OCc2ccccc2)c1=O>>CCOC(=O)NNc1nc2ccc(-n3ccnc3)cc2n(O)c1=O,[Pd],CN(C)C=O,O,,,test
US06265753B1,C#Cc1ccccc1.O=C(Nc1ccc(I)c(I)c1)C(F)(F)F.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>Nc1ccc(C#Cc2ccccc2)c(C#Cc2ccccc2)c1,I[Cu]I,,,CCN(CC)CC,,test
US20080312232A1,Cc1noc(-c2cc3nccc(Cl)c3s2)n1.Nc1ccc(O)c(F)c1>>Cc1noc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)n1,,ClC(Cl)Cl,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20090198063A1,COc1cnc2ccc(=O)n(CC3OCCO3)c2n1>>COc1cnc2ccc(=O)n(CC=O)c2n1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20070249612A1,NNc1ncc(-c2ccccc2)nc1Br.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]nc2c(Br)nc(-c3ccccc3)cn12,,C1CCOC1,CCOC(C)=O,O=S(=O)(O)C(F)(F)F,,test
US20140206682A1,Nc1cc(C(=O)N[C@@H]2c3ccccc3C[C@@H]2O)ccc1F.O=C(O)c1cnc2cc(F)ccn12>>O=C(N[C@@H]1c2ccccc2C[C@@H]1O)c1ccc(F)c(NC(=O)c2cnc3cc(F)ccn23)c1,,ClCCl,c1ccncc1,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20110178302A1,COCCl.Oc1ccc2nc(-c3ccc(I)cc3)sc2c1>>COCc1ccc2nc(-c3ccc(I)cc3)sc2c1,,CCN(CC)CC,,CN(C)C=O,[H-].[Na+],test
US20060276533A1,COC(=O)c1sc(Br)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C1COC(C)(C)OC1>>COC(=O)c1sc(Br)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C(CO)CO,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20070032478A1,CN1CCN(c2ccc(N)cc2)CC1.Cc1cc(C(=O)Nc2cccc(C(=O)c3ccc4c(c3)NC(=O)C4=CO)c2)n(C(C)(C)C)n1>>Cc1cc(C(=O)Nc2cccc(C(=O)c3ccc4c(c3)NC(=O)C4=CNc3ccc(N4CCN(C)CC4)cc3)c2)n(C(C)(C)C)n1,,C1CCOC1,,,,test
US20130023541A1,CC(C)OC(=O)c1cccnc1N1CCN(Cc2ccc(C=O)cc2)CC1.CCNCc1c(F)cccc1Cl>>CCN(Cc1ccc(CN2CCN(c3ncccc3C(=O)OC(C)C)CC2)cc1)Cc1c(F)cccc1Cl,,ClCCCl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05559230,CCOC(=O)COc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCCc3ccccc32)cc1.N>>NC(=O)COc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCCc3ccccc32)cc1,,CO,,[Cl-].[NH4+],,test
US20120028973A1,CC(C)[Si](Cl)(C(C)C)C(C)C.OC[C@H](O)COCc1ccccc1>>CC(C)[Si](OC[C@H](O)COCc1ccccc1)(C(C)C)C(C)C,,CN(C)C=O,,c1c[nH]cn1,,test
US20060025433A1,CCN(CC)S(F)(F)F.O=[N+]([O-])c1cnc(NCc2ccccc2OC(F)(F)F)nc1NC[C@@H]1CC[C@@H](N2CC(O)C2)CC1>>O=[N+]([O-])c1cnc(NCc2ccccc2OC(F)(F)F)nc1NC[C@@H]1CC[C@@H](N2CC(F)C2)CC1,,ClCCl,,O=C([O-])O.[Na+],,test
US04387158,CCCCC(CC)CO.COC(=O)CCCC(C)(C)c1ccc(O)cc1O>>CCCCC(CC)COC(=O)CCCC(C)(C)c1ccc(O)cc1O,,CCOCC,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100022616A1,COc1ccccc1OC(c1ccccc1)C1CCN(C(=O)OC(C)(C)C)C1>>COc1ccccc1OC(c1ccccc1)C1CCNC1,,CCO,Cl,O=C(O)C(F)(F)F,,test
US20100010040A1,CC(C)(C)[Si](C)(C)O[C@@H](CBr)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12.CCN(C(C)C)C(C)C.NCCCCCCCCCN1CCC(Cn2cnc(C(O)(c3ccccc3)c3ccccc3)n2)CC1>>CC(C)(C)[Si](C)(C)O[C@@H](CNCCCCCCCCCN1CCC(Cn2cnc(C(O)(c3ccccc3)c3ccccc3)n2)CC1)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12.N,,ClCCl,,CS(C)=O,,test
US20150252072A1,CC(C)[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)N1c2ncccc2C[C@H]1CNc1ccc2ccccc2c1.Cl>>CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ncccc2C[C@H]1CNc1ccc2ccccc2c1)C(C)C.Cl,,C1COCCO1,,,,test
US20100210704A1,COc1cc(O)nn1-c1cc(SCC(F)(F)F)c(C)cc1F.FC(F)=C(F)OC(F)(F)F>>COc1cc(OC(F)(F)C(F)OC(F)(F)F)nn1-c1cc(SCC(F)(F)F)c(C)cc1F,,CN(C)C=O,,CCN(CC)CC,CCOC(C)=O,test
US20160031903A1,CC(C)(C)OC(=O)N1CC(C(=O)C(F)(F)F)C1.C[Si](C)(C)C(F)(F)F>>CC(C)(C)OC(=O)N1CC(C(O)(C(F)(F)F)C(F)(F)F)C1,,C1CCOC1,CCOC(C)=O,Cl,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US04198349,COC(=O)c1ccc(C=O)cc1.Nc1cc(Cl)cc(Cl)c1>>COC(=O)c1ccc(C=Nc2cc(Cl)cc(Cl)c2)cc1,,CCO,,,,test
US20110312963A1,CC(C)(C)OC(=O)Nc1nccc(Oc2ccc(NC(=O)OC(C)(C)C)c3ccccc23)n1>>Nc1nccc(Oc2ccc(N)c3ccccc23)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120316151A1,CC(C)(C)OC(=O)N1CC[C@@H](CC(=O)NN)C1.O=C=Nc1ccc(Br)cc1F>>CC(C)(C)OC(=O)N1CC[C@@H](CC(=O)NNC(=O)Nc2ccc(Br)cc2F)C1,,ClCCl,,,,test
US20040214808A1,COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(CCCCC#N)CC3)cc1.NO>>COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(CCCCC(=N)NO)CC3)cc1,,CCO,,CCN(CC)CC,Cl,test
US08629147B2,COc1ncccc1-c1ccc(O)c(-c2nc3cc(C(=O)O)c(F)cc3[nH]2)c1.NCCc1c[nH]cn1>>COc1ncccc1-c1ccc(O)c(-c2nc3cc(C(=O)NCCc4c[nH]cn4)c(F)cc3[nH]2)c1,,C1CCOC1,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100056490A1,CN(C)CC(=O)Nc1ccc(C[C@@H]2CS(=O)(=O)C[C@H]3[C@H]2OC(=O)N3Cc2cccc(C(C)(C)C)c2)cc1F>>CN(C)CC(=O)Nc1ccc(C[C@@H]2CS(=O)(=O)C[C@H](NCc3cccc(C(C)(C)C)c3)[C@H]2O)cc1F,,Cc1ccccc1,,,,test
US20110034492A1,CC(=O)Nc1nc(O)ncc1F.CCN=C=O>>CCNC(=O)n1cc(F)c(NC(C)=O)nc1=O,,C1CCOC1,,,,test
US05432169,C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](OCCOCC(O)CO)CC[C@@]43C)[C@@]1(O)CC[C@@H]2c1ccoc1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCC(O)COCCO[C@H]2CC[C@@]3(C)[C@H](CC[C@@H]4[C@@H]3CC[C@]3(C)[C@@H](c5ccoc5)CC[C@]43O)C2)cc1,,c1ccncc1,,CCOC(C)=O,O,test
US20160009712A1,CC1CO1.Clc1c(Br)cc(OC[C@@H]2CCCNC2)c2cncn12>>CC(O)CN1CCC[C@@H](COc2cc(Br)c(Cl)n3cncc23)C1,,ClCCl,,O,,test
US20070225303A1,CCOC(=O)C(F)(F)F.NC(=O)c1c(N)ncn1Cc1ccccc1>>Oc1nc(C(F)(F)F)nc2ncn(Cc3ccccc3)c12,,CCO,,CC(=O)O,[Na],test
US04112236,CCCCCC(C=CCN(CCCc1ccc(C(=O)OCC)cc1)S(C)(=O)=O)OC(C)=O>>CCCCCC(O)C=CCN(CCCc1ccc(C(=O)O)cc1)S(C)(=O)=O,,CO,O,[Na+].[OH-],,test
US20060128790A1,COc1ccc(NCC2(C(=O)O)CCC2)c(C)c1C>>COc1cc2c(c(C)c1C)NCC1(CCC1)C2=O,,Cc1ccccc1,,O=P(O)(O)O,,test
US20110065708A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.Clc1ccc2nnc(C3(c4ccc5ncccc5c4)CC3)n2n1>>CC(=O)c1ccc2nnc(C3(c4ccc5ncccc5c4)CC3)n2n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,CCOC(C)=O,,,test
US20130115190A1,C1COCCN1.COc1cc2c(Br)c[nH]c(=O)c2cc1F>>COc1cc2c(N3CCOCC3)c[nH]c(=O)c2cc1F,,O,OCCO,CCN(C(C)C)C(C)C,,test
US20140228396A1,Cc1ccncc1C#N.Nc1ccc(F)cn1>>Cc1ccncc1C(=N)Nc1ccc(F)cn1,,C1CCOC1,,[Li]CCCC,,test
US20040122235A1,CCOC(=O)Cc1csc(NC(=O)C(=O)OCC)n1>>CCOC(=O)Cc1csc(NC(=O)C(=O)O)n1,,C1CCOC1,,[Li+].[OH-],,test
US04013651,O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(O)CS[C@H]12.O=S(Cl)Cl>>O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(Cl)CS[C@H]12,,CN(C)C=O,,,,test
US20100249078A1,COC(=O)/C=C/c1ccc([N+](=O)[O-])cc1>>COC(=O)CCc1ccc(N)cc1,[Pd],C1CCOC1,CO,,,test
US20060111375A1,COc1cc2c(Cl)ccnc2cc1OCc1ccccc1.Cc1nc2ccncc2cc1O>>COc1cc2c(Oc3cc4cnccc4nc3C)ccnc2cc1OCc1ccccc1,CN(C)c1ccncc1,Clc1ccccc1Cl,,O,,test
US04144235,CCOc1cscc1C(=O)O.O=S(=O)(Cl)Cl>>CCOc1c(C(=O)O)csc1Cl,,ClC(Cl)Cl,,,,test
US20140296253A1,ClCCCN1CCN(C(c2ccccc2)c2ccccc2)CC1.OC1(c2ccc(Cl)cc2)CCNCC1>>OC1(c2ccc(Cl)cc2)CCN(CCCN2CCN(C(c3ccccc3)c3ccccc3)CC2)CC1,,CN(C)C=O,,,,test
US20160145271A1,COC(=O)C(=O)C(C)(C)C(=O)OC.Cc1ccc2c(C(=N)NN)nn(Cc3cccc(F)c3F)c2n1>>COC(=O)C(C)(C)c1nnc(-c2nn(Cc3cccc(F)c3F)c3nc(C)ccc23)nc1O,,CCO,,,,test
US20070185103A1,CCOC(=O)c1cncc(Cc2ccccc2)c1>>CCOC(=O)C1CNCC(CC2CCCCC2)C1,O=[Pt]=O,CCO,Cl,,,test
US20080255202A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.Cc1cccc(CC(N)=O)c1>>Cc1cccc(CC(N)=S)c1,,C1CCOC1,,,,test
US20160096834A1,CC(C)(C)c1nnc(C(=O)O)o1.CN1CC=C(c2nc3c(-c4ccc(CN)c(F)c4)ccnc3[nH]2)CC1>>CN1CC=C(c2nc3c(-c4ccc(CNC(=O)c5nnc(C(C)(C)C)o5)c(F)c4)ccnc3[nH]2)CC1,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20060235030A1,CN(C)CCCN.Cc1ccc(C(=O)Nc2ccc(F)cc2)cc1-c1nc(S(C)=O)nc2c1CNC(=O)N2c1c(F)cccc1F>>Cc1ccc(C(=O)Nc2ccc(F)cc2)cc1-c1nc(NCCCN(C)C)nc2c1CNC(=O)N2c1c(F)cccc1F,,C1CCOC1,,,,test
US05948784,CCOC(=O)C1CCN(c2nc(N3CCC(n4c(=O)c5cc(C)ccc5n(C)c4=O)CC3)c3cc(OC)c(OC)cc3n2)CC1>>COc1cc2nc(N3CCC(C(=O)O)CC3)nc(N3CCC(n4c(=O)c5cc(C)ccc5n(C)c4=O)CC3)c2cc1OC,,CO,,[Na+].[OH-],,test
US06277877B1,N#Cc1ccc2[nH]c(C(=O)O)cc2c1.N[C@@H](Cc1ccccc1)C(=O)N1CCSC1>>N#Cc1ccc2[nH]c(C(=O)N[C@@H](Cc3ccccc3)C(=O)N3CCSC3)cc2c1,,CCOC(C)=O,Cl,,,test
US20120071489A1,CC(C)(C)OC(=O)CBr.CC(C)(C)c1ccccc1N1CCN(C(=O)c2ccc(N3CCNC3=O)cc2)CC1>>CC(C)(C)OC(=O)CN1CCN(c2ccc(C(=O)N3CCN(c4ccccc4C(C)(C)C)CC3)cc2)C1=O,,CN(C)C=O,,O,[H-].[Na+],test
US04465768,O=S(Cl)Cl.[N-]=[N+]=Nc1ccc(C(=O)O)cc1>>[N-]=[N+]=Nc1ccc(C(=O)Cl)cc1,,CN(C)C=O,,,,test
US04168269,CC(=O)Cl.O=C1Nc2ccccc2Nc2cscc21>>CC(=O)N1c2ccccc2NC(=O)c2cscc21,,c1ccccc1,,,,test
US20150225367A1,CN.O=S(=O)(c1ccccc1)n1cc(-c2ccc(Cl)nc2)c2ccc(F)cc21>>CNc1ccc(-c2cn(S(=O)(=O)c3ccccc3)c3cc(F)ccc23)cn1,,CS(C)=O,,,,test
US20080090853A1,CCOC(=O)C(C)(C)N1CCC(NCc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)CC1.O=C(O)Cn1c(CCc2ccc(F)cc2F)nc(=O)c2ccccc21>>CCOC(=O)C(C)(C)N1CCC(N(Cc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)C(=O)Cn2c(CCc3ccc(F)cc3F)nc(=O)c3ccccc32)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060154955A1,CC(C)(C)OC(=O)Nc1ccc(-c2ccccc2)nc1Br.O=CN1CCCCC1>>CC(C)(C)OC(=O)Nc1ccc(-c2ccccc2)nc1C=O,,C1CCOC1,,[Li]CCCC,,test
US20130345181A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cn1cc(-c2[nH]c3cc(Br)ncc3c2Cl)cn1>>Cn1cc(-c2c(Cl)c3cnc(Br)cc3n2C(=O)OC(C)(C)C)cn1,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,,test
US20030206326A1,BrCCCc1ccccc1.c1cc(-c2ccncc2)ccn1>>[Br-].c1ccc(CCC[n+]2ccc(-c3ccncc3)cc2)cc1,,Cc1ccccc1,,,,test
US05173493,Cc1[nH]cnc1CC1CCc2cc3ccccc3n2C1=O.ClCc1ccccc1>>Cc1c(CC2CCc3cc4ccccc4n3C2=O)ncn1Cc1ccccc1,,CN(C)C=O,O,[H-].[Na+],,test
US20080262042A1,CN(Cc1c[nH]c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C.O=S(=O)(Cl)N1CCCCC1>>CN(Cc1cn(S(=O)(=O)N2CCCCC2)c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C,,C1CCOC1,O,C1COCCOCCOCCOCCO1,[H-].[Na+],test
US05773448,O=C1N(CCCl)c2ccc(F)cc2C12SCCCS2>>O=C1Cc2cc(F)ccc2N1CCCl,[Ni],C1CCOC1,CCO,,,test
US20090291079A1,CC(C)(C)OC(=O)CNC1CCN(c2nc(-c3ccc(NC(=O)Nc4ccncc4)cc3)nc(N3CC4CCC(C3)O4)n2)CC1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C(O)CNC1CCN(c2nc(-c3ccc(NC(=O)Nc4ccncc4)cc3)nc(N3CC4CCC(C3)O4)n2)CC1,,ClCCl,,,,test
US20090325912A1,CCc1cc2c(cc1CC)CC(NC[C@H](O)c1ccc(O)c3[nH]c(=O)ccc13)C2.Cc1ccc(S(=O)(=O)O)cc1>>CCc1cc2c(cc1CC)CC(NC[C@H](O)c1ccc(O)c3[nH]c(=O)ccc13)C2.Cc1ccc(S(=O)(=O)O)cc1,,CCOC(C)=O,,O,,test
US20100029638A1,COC(=O)c1ccc(N)cc1.Clc1ncnc(Cl)n1>>COC(=O)c1ccc(Nc2ncnc(Cl)n2)cc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US07071175B1,CCOC(=O)C(CSC(C)=O)Cc1cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc1C>>Cc1cc(N)ncc1CC(CS)C(=O)O,,Cl,,,,test
US20120253035A1,CC(C)(C)NS(=O)(=O)c1cncc(Br)c1.CC(C)OB(OC(C)C)OC(C)C>>CC(C)(C)NS(=O)(=O)c1cncc(B(O)O)c1,,C1CCOC1,O,CCCCCC,[Li]CCCC,test
US20020065307A1,BrBr.CC(C)(C)c1nc2ccc(N)cc2[nH]1>>CC(C)(C)c1nc2ccc(N)c(Br)c2[nH]1,,CC(=O)O,,,,test
US20100087408A1,CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C>>CC(=O)OCC(=O)C1(O)CCC2C3C[C@H](C)C4=CC(=O)C=C[C@]4(C)C3=CC[C@@]21C,,C1CCOC1,CN(C)C=O,,,test
US20040082583A1,C1=COCCC1.O=[N+]([O-])c1ccc(O)cc1F>>O=[N+]([O-])c1ccc(OC2CCCCO2)cc1F,,ClCCl,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US05424329,COC(=O)c1cc2cc(OC)ccc2[nH]1.CS(C)=O.Cl>>COC(=O)c1[nH]c2ccc(OC)cc2c1[S+](C)C.[Cl-],,CO,,,,test
US20090082365A1,CC(C)(C)C(=O)Cl.COc1ccc(C(=O)O)c(N)c1>>COc1ccc(C(=O)O)c(NC(=O)C(C)(C)C)c1,,ClCCl,,CCN(CC)CC,O,test
US20140088078A1,C#CCOc1cccc(NC(=O)C(C)(C)C)c1C(=O)OC>>COC(=O)c1c(NC(=O)C(C)(C)C)ccc2c1OCC=C2,,Cc1ccccc1,,,,test
US06191124B1,BrCCc1ccccc1.O=Cc1cnc2sc3c(n12)CCC3>>OC(CCc1ccccc1)c1cnc2sc3c(n12)CCC3,,C1CCOC1,,,,test
US20150018328A1,NC(=O)c1cncc(C(F)(F)F)n1>>N#Cc1cncc(C(F)(F)F)n1,,O=P(Cl)(Cl)Cl,,,,test
US20100197670A1,CCN=C=S.NC1=Nc2ccccc2CS1>>CCNC(=S)NC1=Nc2ccccc2CS1,,Cc1ccccc1,,ClCCl,,test
US20130005707A1,CC(=O)c1cc(Br)cnc1Cl.NN>>Cc1n[nH]c2ncc(Br)cc12,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20130157977A1,Cc1c(Cl)cccc1CBr.O=[N+]([O-])c1cc(Br)c2nc(C(F)(F)F)[nH]c2c1>>Cc1c(Cl)cccc1Cn1c(C(F)(F)F)nc2c(Br)cc([N+](=O)[O-])cc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070185103A1,COC(=O)c1ccc(=O)n(C2CCCCC2)c1>>O=C(O)c1ccc(=O)n(C2CCCCC2)c1,,C1CCOC1,CO,[Li+].[OH-],,test
US20090137595A1,N#CC1(c2cccc(C(=O)Nc3cccc(Oc4ccc5nc(N)cn5n4)c3)c2)CC1.O=C(O)c1ccncc1>>N#CC1(c2cccc(C(=O)Nc3cccc(Oc4ccc5nc(NC(=O)c6ccncc6)cn5n4)c3)c2)CC1,CN(C)C=O,CN1CCCC1=O,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US20120142686A1,CN(C)C=O.CNC(=O)c1c2cc(C3CC3)c(N(CCN)S(C)(=O)=O)cc2nn1-c1ccc(Br)cc1.O=C(O)CCC(=O)O>>CNC(=O)c1c2cc(C3CC3)c(N(CCCNC(=O)CCC(=O)O)S(C)(=O)=O)cc2nn1-c1ccc(Br)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070238775A1,NC(c1ccccc1)c1ccccc1.O=C(Cl)C(=O)c1c[nH]c2ccccc12>>O=C(NC(c1ccccc1)c1ccccc1)C(=O)c1c[nH]c2ccccc12,,CC#N,,,,test
US20030018046A1,NCc1ccc(CN(Cc2nc3ccccc3[nH]2)C2CCCc3cccnc32)cc1.O=Cc1ccccc1O>>Oc1ccccc1CNCc1ccc(CN(Cc2nc3ccccc3[nH]2)C2CCCc3cccnc32)cc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100286123A1,COc1cc2c(cc1C#N)CCOC2CN1CCN(C(=O)[O-])C(C(C)(C)C)C1>>COc1cc2c(cc1C#N)CCOC2CN1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070161654A1,CCO.Cc1onc(-c2ccccc2)c1-c1cn(-c2ccc([N+](=O)[O-])cc2)c(CCl)n1>>CCOCc1nc(-c2c(-c3ccccc3)noc2C)cn1-c1ccc([N+](=O)[O-])cc1,,CCO,CO,C,C[O-].[Na+],test
US03974161,CCOC(=O)c1nc2nc3cc(OC)c(OC)cc3cc2c(=O)[nH]1.CI>>CCOC(=O)c1nc2nc3cc(OC)c(OC)cc3cc2c(=O)n1C,,CN(C)C=O,,[H-].[Na+],,test
US20130059834A1,CI.Ic1n[nH]c2ccccc12>>Cn1nc(I)c2ccccc21,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20060178418A1,COc1ccc(NS(=O)(=O)c2ccc(OC)c3c2c2ccccc2n3C=O)cc1>>COc1ccc(NS(=O)(=O)c2ccc(OC)c3[nH]c4ccccc4c23)cc1,,C1CCOC1,,[BH4-].[Na+],,test
US20100010035A1,CC(C)=O.CCOC(=O)Cn1nc(C)cc1C>>CC(=O)CC(=O)Cn1nc(C)cc1C,,CN(C)C=O,,Cl,[H-].[Na+],test
US20020052408A1,OC[C@H]1O[C@@H]1c1ccccc1.Oc1ccccc1>>OC[C@@H](O)[C@@H](Oc1ccccc1)c1ccccc1,,O,,[Na+].[OH-],,test
US20120028959A1,C=[N+]=[N-].Nc1c(C(=O)O)cc(Cl)cc1[N+](=O)[O-]>>COC(=O)c1cc(Cl)cc([N+](=O)[O-])c1N,,CO,,,,test
US20160145247A1,CC(C(=O)OC(C)(C)C)c1ccccc1OCc1cccc(-c2cccc(CNC(=O)OC(C)(C)C)c2)c1>>CC(C(=O)O)c1ccccc1OCc1cccc(-c2cccc(CN)c2)c1,,C1COCCO1,,Cl,,test
US20110301148A1,COC(=O)C1CNCCC1=O.CS(=O)(=O)Cl>>COC(=O)C1CN(S(C)(=O)=O)CCC1=O,,CCOC(C)=O,ClCCl,CCN(CC)CC,Cl,test
US20100204449A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@@H](O)[C@H](N)C(=O)OC(C)(C)C>>C[C@@H](O)[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,Cl,test
US20010051620A1,COc1cc(N)c(Cl)cc1Cl.COc1cc2cc3c(Cl)c(C#N)cnc3nc2cc1OC>>COc1cc(Nc2c(C#N)cnc3nc4cc(OC)c(OC)cc4cc23)c(Cl)cc1Cl,,CCOCCO,,Cl,c1ccncc1,test
US20080269200A1,NC(=O)c1cc(-c2ccccc2)cc2cc[nH]c12.O=C1CCCCC1>>NC(=O)c1cc(-c2ccccc2)cc2c(C3=CCCCC3)c[nH]c12,,CO,,[K+].[OH-],,test
US20110274638A1,CC(C)(C)OC(=O)CC(O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>O=C(O)CC(O)c1c[nH]cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100120801A1,CC(C)(C)OC(=O)N1CCC(c2nc(-c3ccc(F)c(F)c3)c[nH]2)CC1.CC(C)(C)[Si](C)(C)OCCBr>>CC(C)(C)OC(=O)N1CCC(c2nc(-c3ccc(F)c(F)c3)cn2CCO[Si](C)(C)C(C)(C)C)CC1,,C1CCOC1,,[K+].[OH-],,test
US20030105099A1,COC(=O)[C@H](C/C=C/c1ccccc1)[C@H](O)C(=O)N1CCOCC1>>COC(=O)[C@H](CCCc1ccccc1)[C@H](O)C(=O)N1CCOCC1,[Pd],CO,,,,test
US20050261327A1,COCCl.OCc1ccccc1Br>>COCOCc1ccccc1Br,,C1CCOC1,,[H-].[Na+],,test
US20150291563A1,CC(C)(C)OC(=O)N1CCN(c2ccc(C3CC(C(O)(C(F)(F)F)C(F)(F)F)=NN3c3ccccc3Cl)cn2)CC1.Cl>>Cl.OC(C1=NN(c2ccccc2Cl)C(c2ccc(N3CCNCC3)nc2)C1)(C(F)(F)F)C(F)(F)F,,CCOC(C)=O,,,,test
US20080153852A1,Brc1ccsc1.O=Cc1ccccc1B(O)O>>O=Cc1ccccc1-c1ccsc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20030073846A1,O=Cc1cc(OC[C@@H](O)CN(Cc2ccccc2)[C@H](CO)Cc2ccc(O)cc2)ccc1OCc1ccccc1>>OCc1cc(OC[C@@H](O)CN(Cc2ccccc2)[C@H](CO)Cc2ccc(O)cc2)ccc1OCc1ccccc1,,CO,,[BH4-].[Na+],,test
US20110053916A1,CC1CC1C(=O)CC#N.NN>>C[C@@H]1C[C@H]1c1cc(N)n[nH]1,,CCO,,O,,test
US20110245205A1,CC(=O)Nc1cc(Nc2nccc(OC3CCN(C(=O)OC(C)(C)C)CC3)n2)cc(-c2cnc(C3(O)CCC3)s2)c1>>CC(=O)Nc1cc(Nc2nccc(OC3CCNCC3)n2)cc(-c2cnc(C3(O)CCC3)s2)c1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US04927829,C1CSCCN1.CCOC(=O)c1ccc2c(S)cccn2c1=O.O=C(Cl)OC(Cl)(Cl)Cl>>CCOC(=O)c1ccc2c(SC(=O)N3CCSCC3)cccn2c1=O,,CCN(CC)CC,,C1CCOC1,,test
US20080280948A1,COc1cc(NC(N)=S)ccc1-n1cnc(C)c1.O=C1CCCCC1Cl>>COc1cc(Nc2nc3c(s2)CCCC3)ccc1-n1cnc(C)c1,,CCO,,,,test
US20150045378A1,COc1cc(C(O)C2CC2)ccn1>>COc1cc(C(=O)C2CC2)ccn1,,CS(C)=O,,CCN(CC)CC,O,test
US20110152235A1,O=C1CSC(=O)N1.O=Cc1cccc(Br)n1>>O=C1NC(=O)/C(=C/c2cccc(Br)n2)S1,,Cc1ccccc1,,C1CCNCC1,CC(=O)O,test
US20060111366A1,CC1(C)CC2CC(C)(CN2C(=O)c2c[nH]c3c([N+](=O)[O-])cccc23)C1>>CC1(C)CC2CC(C)(CN2C(=O)c2c[nH]c3c(N)cccc23)C1,[Pd],CO,,,,test
US05866568,CC(C)Cc1ccc(B(O)O)cc1.COc1nc(C)cnc1N(COCC[Si](C)(C)C)S(=O)(=O)c1cnccc1Cl>>COc1nc(C)cnc1N(COCC[Si](C)(C)C)S(=O)(=O)c1cnccc1-c1ccc(CC(C)C)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,CCOCC,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20100323994A1,COc1ccc(CNc2ccc(C)cn2)cc1.Clc1cc(Br)c2nccn2n1>>COc1ccc(CN(c2ccc(C)cn2)c2cc(Cl)nn3ccnc23)cc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20080113985A1,O=S(=O)(Cl)c1ccc(Br)cc1.OCC1CCCN1>>O=S(=O)(c1ccc(Br)cc1)N1CCC[C@@H]1CO,,ClCCl,,O=C([O-])O.[Na+],,test
US20080269305A1,O=C(O)C(Cc1ccccc1)C(=O)NOCc1ccccc1.O=C1CCC(=O)N1O>>O=C(NOCc1ccccc1)C(Cc1ccccc1)C(=O)ON1C(=O)CCC1=O,,CC#N,,ClCCCl,,test
US20130338140A1,CC(C)(C)OC(=O)NCCC(c1ccc(Cl)c(Cl)c1)N1C(=O)c2ccccc2C1=O>>CC(C)(C)OC(=O)NCCC(N)c1ccc(Cl)c(Cl)c1,,CO,,NN,,test
US20060148805A1,COC(=O)Cn1c(C(=O)C(C)(C)C)nc2ccc(OC)cc21>>COc1ccc2nc(C(=O)C(C)(C)C)n(CC(=O)O)c2c1,,CO,,[Na+].[OH-],,test
US20050153970A1,C[C@H]([C@H]1CO1)N(Cc1ccccc1)Cc1ccccc1.Fc1ccc(CCCNCC(F)(F)F)cc1>>C[C@H]([C@@H](O)CN(CCCc1ccc(F)cc1)CC(F)(F)F)N(Cc1ccccc1)Cc1ccccc1,,CCO,,,,test
US06235742B1,CCCc1nn(C)c2c(=O)[nH]c(Cc3ccc(N)cc3)nc12.CCO/C=C/C(=O)Cl>>CCCc1nn(C)c2c(=O)[nH]c(Cc3ccc(NC(=O)/C=C/OCC)cc3)nc12,,c1ccncc1,,,,test
US04447522,NCCC(=O)O.O=C(CBr)c1ccccc1.S=C=S>>O=C(O)CCN1C(=S)SCC1(O)c1ccccc1,,CO,O,[K+].[OH-],,test
US20100222319A1,C1CCOC1.CC(C)(C)OC(=O)Nc1ccc(CN)cn1.CCNc1nc(-c2ccc(N)cc2)ccc1C(=O)NCCN1CCCCC1>>CCNc1nc(-c2ccc(NC(=O)NCc3ccc(NC(=O)OC(C)(C)C)nc3)cc2)ccc1C(=O)NCCN1CCCCC1,CN(C)c1ccncc1,,,CCN(CC)CC,,test
US20110281865A1,CC(=O)c1ccc2nnn(Cc3ccc4ncccc4c3)c2n1.NNC(=O)c1ccncc1>>CC(=NNC(=O)c1ccncc1)c1ccc2nnn(Cc3ccc4ncccc4c3)c2n1,,CCO,,,,test
US20120322837A1,CCC(C=CC(=O)[O-])CC>>CCC(CC)CCC(=O)O,[Pd],C1CCOC1,CCO,,,test
US20060264474A1,CC(N)c1cccc(-c2cc(CCc3ccc(F)cc3)n(C)n2)c1.O=S(=O)(Cl)NCC(F)(F)F>>CC(NS(=O)(=O)NCC(F)(F)F)c1cccc(-c2cc(CCc3ccc(F)cc3)n(C)n2)c1,,ClCCl,,CCN(CC)CC,,test
US20020193365A1,Cc1ccc(S(=O)(=O)OC[C@H]2COc3ccc4nc(C)oc4c3O2)cc1.O=c1[nH]c2ccccc2n1C1CCNCC1>>Cc1nc2ccc3c(c2o1)OC(CN1CCC(n2c(=O)[nH]c4ccccc42)CC1)CO3,,CS(C)=O,,,,test
US20120327357A1,OCCCCC#Cc1ccc(C=Cc2ccc(C=Cc3ccc(C#CCCCCO)cc3)c3ccccc23)cc1>>OCCCCCCc1ccc(CCc2ccc(CCc3ccc(CCCCCCO)cc3)c3ccccc23)cc1,[Pd],C1CCOC1,,,,test
US20110171159A1,CC(C)c1ccc([C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1Cc1ccc2c(c1)N(Cc1ccccc1)CCC2>>CC(C)c1ccc([C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1Cc1ccc2c(c1)NCCC2,[Pd],CO,,Cl,,test
US20110118283A1,N#CCc1ncc(Br)cn1.O=Cc1cccc(Cl)c1F>>N#C/C(=C/c1cccc(Cl)c1F)c1ncc(Br)cn1,,CO,,C[O-].[Na+],,test
US20120053166A1,CC(C)N1[C@@H](C)CNC[C@H]1C.O=S(=O)(c1ccccc1)n1ncc2c(-c3nnc(CBr)o3)cc(Br)cc21>>CC(C)N1[C@@H](C)CN(Cc2nnc(-c3cc(Br)cc4c3cnn4S(=O)(=O)c3ccccc3)o2)C[C@H]1C,,CC#N,ClCCl,CCN(C(C)C)C(C)C,[I-].[Na+],test
US04153719,CCOC(=O)c1ccc(C=Cc2ccc(OC)cc2)cc1>>COc1ccc(C=Cc2ccc(CO)cc2)cc1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US04217305,CC(NCc1ccccc1)C1COc2ccccc2O1.NS(=O)(=O)c1cc(C(=O)CBr)ccc1OCc1ccccc1>>CC(C1COc2ccccc2O1)N(CC(=O)c1ccc(OCc2ccccc2)c(S(N)(=O)=O)c1)Cc1ccccc1,,CCC(C)=O,,,,test
US20060135782A1,CC(C)(C)OC(=O)Nc1nc2ccc([N+](=O)[O-])cc2s1>>CC(C)(C)OC(=O)Nc1nc2ccc(N)cc2s1,[Pd],CN(C)C=O,,[H][H],,test
US20090181942A1,COc1c(C(O)c2cc(Cl)ccc2N)cccc1C(F)(F)F.COc1ccc(C=O)c(OC)c1>>COc1ccc(CNc2ccc(Cl)cc2C(O)c2cccc(C(F)(F)F)c2OC)c(OC)c1,,CC(=O)O,,[BH4-].[Na+],,test
US20010025042A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc2c(c1)CCN2>>COc1ccc2c(c1)CCN2C(=O)OC(C)(C)C,,C1CCOC1,,,,test
US20060004052A1,Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O.O=C(O)c1cccc(F)c1F>>O=C(Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O)c1cccc(F)c1F,,CN(C)C=O,ClCCl,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060063820A1,O=C(O)COc1cccc(Cl)c1.OCc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl>>O=C(COc1cccc(Cl)c1)OCc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20030220324A1,CN(C)C(=O)c1ccccc1N1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)OC(C)(C)C)CC1>>CN(C)C(=O)c1ccccc1N1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@@H]2Cc3ccccc3CN2)CC1,,CCOC(C)=O,,Cl,,test
US04579947,Cl.Cl.NCCCN1CCN(Cc2ccc(Cl)cc2)CC1.O=C=Nc1c(Cl)cccc1Cl>>Cl.Cl.O=C(NCCCN1CCN(Cc2ccc(Cl)cc2)CC1)Nc1c(Cl)cccc1Cl,,ClCCl,,CCN(CC)CC,Cl,test
US20140350011A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2cccc(-c3nc4c(N[C@@H]5[C@H]6C=C[C@H](C6)[C@@H]5C(N)=O)c(Cl)cnc4[nH]3)c2)CC1>>NC(=O)[C@@H]1[C@H](Nc2c(Cl)cnc3[nH]c(-c4cccc(C(=O)N5CCNCC5)c4)nc23)[C@H]2C=C[C@@H]1C2,,ClCCl,O=C(O)C(F)(F)F,,,test
US20090137595A1,N#CC1(c2cccc(C(=O)O)c2)CCC1.Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c(Cl)cc1F>>N#CC1(c2cccc(C(=O)Nc3cc(Oc4ccc5nc(NC(=O)C6CC6)cn5n4)c(Cl)cc3F)c2)CCC1,CN(C)C=O,CN1CCCC1=O,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US20050096343A1,CC(=O)NC[C@H]1CN(c2ccc(NC3CCNCC3)c(F)c2)C(=O)O1.O=C(O)c1cn(C2CC2)c2nc(Cl)c(F)cc2c1=O>>CC(=O)NC[C@H]1CN(c2ccc(NC3CCN(c4nc5c(cc4F)c(=O)c(C(=O)O)cn5C4CC4)CC3)c(F)c2)C(=O)O1,,CS(C)=O,,CCN(CC)CC,C[Si](C)(C)Cl,test
US20090197871A1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2cccc(-c3cccc(C=O)c3)c2C)c1.CN1CCNCC1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2cccc(-c3cccc(CN4CCN(C)CC4)c3)c2C)c1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20080274907A1,CCN(CCCC(=O)[O-])c1cc(O)c(-c2c3ccc(=[N+](C)C)cc-3oc3cc(N(C)C)ccc23)cc1OC.ClC(Cl)Cl.O=C1CCC(=O)N1O>>CCN(CCCC(=O)ON1C(=O)CCC1=O)c1cc(O)c(-c2c3ccc(=[N+](C)C)cc-3oc3cc(N(C)C)ccc23)cc1OC.[Cl-],,CN(C)C=O,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20010008890A1,CCCN.O=C(O)c1ccc([N+](=O)[O-])s1>>CCCNC(=O)c1ccc([N+](=O)[O-])s1,,CN(C)C=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20140162985A1,CC=O.O=C1CCCc2cc3c(cnn3-c3ccncc3)cc2C1>>CC=C1C(=O)CCCc2cc3c(cnn3-c3ccncc3)cc21,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20100137362A1,COC(=O)Cl.Cc1cc(Cl)nc(C(=O)NNC(C)C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl>>COC(=O)N(NC(=O)c1nc(Cl)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl)C(C)C,,c1ccncc1,,,,test
US20020147214A1,O=P(Cl)(Cl)Cl.O=c1[nH]cnc2ccc(-c3nnc(C(F)(F)F)o3)cc12>>FC(F)(F)c1nnc(-c2ccc3ncnc(Cl)c3c2)o1,,CCN(CC)CC,,,,test
US20070299068A1,BrCC1CC1.CCOc1ccc2cc(-c3ccc([N+](=O)[O-])cc3)[nH]c2c1>>CCOc1ccc2cc(-c3ccc([N+](=O)[O-])cc3)n(CC3CC3)c2c1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20150218187A1,C=C1CCNCC1.O=C(Cl)OCC1c2ccccc2-c2ccccc21>>C=C1CCN(C(=O)OCC2c3ccccc3-c3ccccc32)CC1,,C1CCOC1,O,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20160145247A1,CC(C)(C)OC(=O)N[C@H](CO)c1cccc(-c2cc(COc3ccccc3CC(=O)O)cc(C(=O)N[C@H]3CCOc4ccccc43)c2)c1>>N[C@H](CO)c1cccc(-c2cc(COc3ccccc3CC(=O)O)cc(C(=O)N[C@H]3CCOc4ccccc43)c2)c1,,C1COCCO1,,Cl,,test
US20050038076A1,COc1ccc(N)cc1.NC(=O)COc1ccc(S(=O)(=O)Cl)cc1OCC(N)=O>>COc1ccc(NS(=O)(=O)c2ccc(OCC(N)=O)c(OCC(N)=O)c2)cc1,,c1ccncc1,,,,test
US20160214956A1,CCOC(=O)c1cnn(-c2cccc(-c3cc(F)ccc3CCc3ccc(OCCCBr)cc3C)n2)c1C(F)(F)F.COc1cn[nH]c1>>CCOC(=O)c1cnn(-c2cccc(-c3cc(F)ccc3CCc3ccc(OCCCn4cc(OC)cn4)cc3C)n2)c1C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070249637A1,COC(=O)[C@@]12C[C@H]1C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](Oc3nc(-c4cc(C)nn4C)nc4ccsc34)C[C@H]1C(=O)N2>>Cc1cc(-c2nc(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)O)C[C@H]5C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N4C3)c3sccc3n2)n(C)n1,,CO,,C1CCOC1,[Li+].[OH-],test
US20150072969A1,CCOC(=O)CC1(c2ccc(OCc3cccc(-c4c(C)cc(O)cc4C)c3)cc2)COC1.Cc1ccc(S(=O)(=O)OC[C@@H]2CCOC2)cc1>>CCOC(=O)CC1(c2ccc(OCc3cccc(-c4c(C)cc(OC[C@@H]5CCOC5)cc4C)c3)cc2)COC1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110028469A1,COC(=O)c1sccc1N.O=S(=O)(Cl)c1ccc(F)cc1F>>COC(=O)c1sccc1NS(=O)(=O)c1ccc(F)cc1F,,ClCCl,,c1ccncc1,,test
US05998433,CN(C)Cc1cc2c(o1)CN(C(=O)/C(=C/c1ccccc1)c1ccccc1)CC2.Cl>>CN(C)Cc1cc2c(o1)CN(C(=O)/C(=C/c1ccccc1)c1ccccc1)CC2.Cl,,CCOC(C)=O,CO,,,test
US20080004300A1,CC(C)(C)OC(=O)N1CCC(CN2CC(C)(C)c3ccc(N)cc32)CC1.COC(=O)C(C)(C)NCc1ccnc2ccccc12.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N1CCC(CN2CC(C)(C)c3ccc(N4C(=O)N(Cc5ccnc6ccccc56)C(C)(C)C4=O)cc32)CC1,,C1CCOC1,,,,test
US20090069222A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)O.N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1ccccc1,,CN(C)C=O,ClCCl,ClCCCl,On1nnc2ccccc21,test
US05153214,COC(=O)CC[C@@H](CCO)CCCCOCc1ccccc1.Oc1cccnc1>>COC(=O)CC[C@H](CCCCOCc1ccccc1)CCOc1cccnc1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05585394,NC1CCCCCC1.O=[N+]([O-])c1ccc(Cl)cc1[N+](=O)[O-]>>O=[N+]([O-])c1ccc(Cl)cc1NC1CCCCCC1,,CCO,,,,test
US05459148,C=C(C)c1nc(CCC)n(Cc2ccc(-c3ccccc3C(=O)C(=O)OC)cc2)c1C(=O)OCC>>C=C(C)c1nc(CCC)n(Cc2ccc(-c3ccccc3C(=O)C(=O)O)cc2)c1C(=O)O,,C1COCCO1,O,[Li+].[OH-],,test
US05559256,CC(C)(C)OC(=O)NC(CC(O)CNC(Cc1ccccc1)C(O)CNC(=O)OCc1ccccc1)c1ccccc1>>NC(=O)OCc1ccccc1,,CO,,,,test
US20160137606A1,O=C(O)c1ccc(Cl)c(Br)n1.OB(O)c1cccc(Cl)c1>>O=C(O)c1ccc(Cl)c(-c2cccc(Cl)c2)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020123497A1,CS(=O)(=O)Oc1ccc2cccc(NC(=O)CCl)c2c1.NCCO>>CS(=O)(=O)Oc1ccc2cccc(NC(=O)CO)c2c1,,CC(=O)OC(C)C,,,,test
US20160108039A1,COCC1C(=O)N2CCC2CN1C(=O)OCc1ccccc1>>COCC1NCC2CCN2C1=O,[Pd],CO,,,,test
US20130331372A1,C=Cc1ccc(-c2ccc(C(=O)OC)cc2C)cc1[N+](=O)[O-]>>CCc1ccc(-c2ccc(C(=O)OC)cc2C)cc1N,[Pd],CO,,,,test
US06479519B1,CCOC(=O)CC(CC(=O)OCC)c1ccc(NC(=O)Cc2ccc(NC(=O)Nc3ccccc3C)c(OC)c2)cc1>>COc1cc(CC(=O)Nc2ccc(C(CC(=O)O)CC(=O)O)cc2)ccc1NC(=O)Nc1ccccc1C,,CO,,Cl,[Na+].[OH-],test
US06596734B1,COc1c(Br)cc(CC(=O)NCCc2ccc(N)c(OCc3ccccc3)c2)cc1Br.O=S(=O)(Cl)c1ccccc1>>COc1c(Br)cc(CC(=O)NCCc2ccc(NS(=O)(=O)c3ccccc3)c(OCc3ccccc3)c2)cc1Br,,c1ccncc1,,ClCCl,,test
US20150252059A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1=N[C@](C)(c2cc([N+](=O)[O-])ccc2F)CS(=O)(=O)[C@@]1(CF)CCI>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1=N[C@](C)(c2cc([N+](=O)[O-])ccc2F)[C@H]2CC[C@]1(CF)S2(=O)=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20120214837A1,CCc1nc(O)cc2cc(OC)c(OC)cc12.COc1ccc2ncc(CCl)cc2c1>>CCc1nc(O)c(Cc2cnc3ccc(OC)cc3c2)c2cc(OC)c(OC)cc12,,C1CCOC1,,Cl,[Li+].[OH-],test
US20150274747A1,BrCc1ccccc1.O[C@@H]1CO[C@@H]2[C@@H](O)CO[C@H]12>>OC1COC2C(OCc3ccccc3)COC12,,CN(C)C=O,,[H-].[Na+],,test
US05254575,CCOC(=O)C(N)=S.COc1cc(C(=O)CBr)cc(Cl)c1OC>>CCOC(=O)c1nc(-c2cc(Cl)c(OC)c(OC)c2)cs1,,CCO,,,,test
US20150274666A1,CS(=O)Cc1cc(Cl)nc(C(F)F)c1.O=C(OO)c1cccc(Cl)c1>>CS(=O)(=O)Cc1cc(Cl)nc(C(F)F)c1,,ClCCl,,,,test
US04766212,CC(=O)Cl.c1ccc2c(c1)OCC[C@H]1NCCO[C@H]21>>CC(=O)N1CCO[C@@H]2c3ccccc3OCC[C@H]21,,ClCCl,,CCN(CC)CC,,test
US05624948,O=C(O)CCc1ccc(CCN2CCCN(c3nc4ccccc4n3Cc3ccc(F)cc3)CCC2)cc1>>O=C(O)CCc1ccc(CCN2CCCN(c3nc4ccccc4n3Cc3ccc(F)cc3)CCC2)cc1,,O,,Cl,[Na],test
US20090197862A1,CN1CCC(n2cc(-c3cnc(N)c(-c4cc5c(Cl)ccc(F)c5cn4)c3)cn2)CC1.Cl.ClCCl>>CN1CCC(n2cc(-c3cnc(N)c(-c4cc5c(Cl)ccc(F)c5cn4)c3)cn2)CC1.Cl.Cl.Cl,,ClCCl,,CCOCC,,test
US05366972,CCN1c2ncccc2C(=O)Nc2c(C)cc(Cl)nc21.OC1CCNC1>>CCN1c2ncccc2C(=O)Nc2c(C)cc(N3CCC(O)C3)nc21,,O,,,,test
US20100120751A1,CC(C)(C)OC(=O)N1CC(=O)Nc2ccc(Cl)cc2C1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)OC(=O)N1CC(=S)Nc2ccc(Cl)cc2C1,,C1CCOC1,,,,test
US20040206940A1,CC(=O)C(C)=O.NCCNCCCNCCN>>CC12NCCN3CCCN(CCN1)C32C,,CC#N,,,,test
US20130345126A1,Cc1ccc(C(N)=O)cc1.O=S(Cl)Cl>>Cc1ccc(C(=O)N=S=O)cc1,,CCOCC,,c1ccncc1,,test
US20110105535A1,COC(=O)CCC(=O)Cl.CS(=O)(=O)O.NNC(N)=O>>COC(=O)CCc1nnc(N)s1,,C1CCOC1,,Cc1ccccc1,,test
US20030083513A1,CC(C)=CCC/C(C)=C/COC(=O)CCl.CCCCCCCCCCCCCCCCCC(=O)NCCCN(C)C.O=C([O-])CCl>>CCCCCCCCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC(=O)OC/C=C(\C)CCC=C(C)C.[Cl-],,ClC(Cl)Cl,,,,test
US20070225280A1,CCOC=C(C#N)C(=O)OCC.NNC1CCOCC1>>CCOC(=O)c1cnn(C2CCOCC2)c1N,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20100009957A1,O=C(N[C@H]1CCCCN(Cc2ccccc2)C1)ON1C(=O)CCC1=O.O=C1[C@H]2NCC[C@H]2N1S(=O)(=O)O>>O=C(N[C@H]1CCCCN(Cc2ccccc2)C1)N1CC[C@@H]2[C@H]1C(=O)N2S(=O)(=O)O,,CC#N,O,O=C([O-])O.[Na+],,test
US06749977B1,C=Cc1ccc(Cn2c(C)nc3ccccc32)cc1.C=O>>C=Cc1ccc(Cn2c(CCO)nc3ccccc32)cc1,,c1ccncc1,,,,test
US20090105474A1,COS(=O)(=O)OC.Nc1cc(Oc2ccccc2)ccc1C(=O)O>>COC(=O)c1ccc(Oc2ccccc2)cc1N,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140051706A1,CCCCC(=O)Cl.C[C@H]1C2N(C(=O)CN(C)N2C(=O)NCc2ccccc2)[C@@H](Cc2ccc(O)cc2)C(=O)N1Cc1cccc2cccnc12>>CCCCC(=O)Oc1ccc(C[C@H]2C(=O)N(Cc3cccc4cccnc34)[C@@H](C)C3N2C(=O)CN(C)N3C(=O)NCc2ccccc2)cc1,,CCOC(C)=O,,C1CCOC1,CCN(CC)CC,test
US06831078B1,CC(C)(C)c1ccc(C2(O)CN(C(c3ccccc3)c3ccccc3)C2)cc1.CS(=O)(=O)Cl>>CC(C)(C)c1ccc(C2(Cl)CN(C(c3ccccc3)c3ccccc3)C2)cc1,,ClCCl,,,,test
US20100022529A1,CCOC(=O)c1c(C)cc(C)[nH]c1=O.OB(O)c1ccc(F)cc1>>CCOC(=O)c1c(C)cc(C)n(-c2ccc(F)cc2)c1=O,,C1COCCO1,,c1ccncc1,,test
US20070173501A1,CC1(C)OC(=O)C=C1O.O=C(Br)C(=O)Br>>CC1(C)OC(=O)C=C1Br,,CN(C)C=O,ClCCCl,,,test
US20130172278A1,CCc1ccc([Mg]Br)cc1.CON(C)C(=O)c1sccc1C>>CCc1ccc(C(=O)c2sccc2C)cc1,,C1CCOC1,,,,test
US20050203147A1,CC(=O)NCC1CN(c2ccc(-c3ccc(CN)cc3)c(F)c2)C(=O)O1.O=Cc1ccnc2ccccc12>>CC(=O)NCC1CN(c2ccc(-c3ccc(CNCc4ccnc5ccccc45)cc3)c(F)c2)C(=O)O1,,C1CCOC1,CN(C)C=O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150005300A1,CCOC(=O)/C(=C/c1ccc(C)s1)N=[N+]=[N-]>>CCOC(=O)c1cc2sc(C)cc2[nH]1,,Cc1ccccc1,,,,test
US20140315885A1,CC(C)(C)OC(=O)N1[C@H]2CC[C@@H]1CNC2.COc1ccc(N=C=O)cc1>>COc1ccc(NC(=O)N2C[C@@H]3CC[C@H](C2)N3C(=O)OC(C)(C)C)cc1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20090270623A1,COc1cc(C(O)C2CCCN([C@@H](C)c3ccc(F)cc3)C2=O)ccc1-n1cnc(C)c1>>COc1cc(/C=C2\CCCN([C@@H](C)c3ccc(F)cc3)C2=O)ccc1-n1cnc(C)c1,,Cc1ccccc1,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20100009975A1,CN(CCN1CCSc2cc([N+](=O)[O-])ccc21)C(=O)Oc1ccccc1>>CN(CCN1CCSc2cc(N)ccc21)C(=O)Oc1ccccc1,[Pd],C1CCOC1,CCO,,,test
US20080318960A1,CC(=O)c1ccc(Br)cc1.NNC(=O)C(NC(=O)c1ccccc1)c1n[nH]c(=O)c2ccccc12>>C/C(=N\NC(=O)C(NC(=O)c1ccccc1)c1n[nH]c(=O)c2ccccc12)c1ccc(Br)cc1,,CCO,,CC(=O)O,,test
US20100004459A1,CCOC(=O)c1cccnc1-c1cccc(C#N)c1O.CS(=O)(=O)OCCCc1ccccc1>>CCOC(=O)c1cccnc1-c1ccc(OCCCc2ccccc2)c(C#N)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20140200227A1,CC(=O)OC1CCc2c1ncc(N)c2N1CCC[C@H](NC(=O)OC(C)(C)C)C1.CC(C)(C)OC(=O)Nc1sc(-c2c(F)cccc2F)nc1C(=O)O>>CC(=O)OC1CCc2c1ncc(NC(=O)c1nc(-c3c(F)cccc3F)sc1NC(=O)OC(C)(C)C)c2N1CCC[C@H](NC(=O)OC(C)(C)C)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130102643A1,CCC(CC)C(=O)c1ccc(NC(C)=O)cc1>>CCC(CC)C(O)c1ccc(NC(C)=O)cc1,,CO,,[BH4-].[Na+],,test
US20020193396A1,CN(C)c1cccc2c(S(=O)(=O)NCCCOCCOCCCN)cccc12.O=[N+]([O-])c1c(Cl)nc2ccccc2c1Cl>>CN(C)c1cccc2c(S(=O)(=O)NCCCOCCOCCCNc3c([N+](=O)[O-])c(Cl)nc4ccccc34)cccc12,,CCO,Cc1ccccc1,CCN(CC)CC,ClCCl,test
US20050020605A1,CCO/N=C(\c1ccc(Br)cc1)C1CCN(C2(C)CCNCC2)CC1.O=C(O)c1cccc2c(Cl)ccnc12>>CCO/N=C(\c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3cccc4c(Cl)ccnc34)CC2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070010542A1,CC1(COC(=O)c2ccccc2)OCC2(CO1)OCCO2>>CC1(CO)OCC2(CO1)OCCO2,,CO,,C1CCOC1,[Na+].[OH-],test
US20140155428A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(C(=O)O)c(F)c1>>CC(C)(C)OC(=O)Nc1ccc(C(=O)O)c(F)c1,,C1COCCO1,O,[Na+].[OH-],,test
US20040242573A1,BrBr.Oc1cccc(CN2CCOCC2)c1>>Oc1cc(CN2CCOCC2)ccc1Br,,CC(=O)O,,,,test
US20150284321A1,Nc1cccc(N)c1.O=C=Nc1ccccc1>>Nc1cccc(NC(=O)Nc2ccccc2)c1,,CCOC(C)=O,,,,test
US20080166359A1,C[C@@H](NC(=O)OC(C)(C)C)C1(O)CN(Cc2ccccc2)C1>>C[C@@H](NC(=O)OC(C)(C)C)C1(O)CNC1,[Pd],CO,,[H][H],,test
US20100249119A1,Cc1ccc(O)cc1NC(=O)c1cccc(C2(C#N)CC2)c1.O=[N+]([O-])c1ccc(Cl)nc1>>Cc1ccc(Oc2ccc([N+](=O)[O-])cn2)cc1NC(=O)c1cccc(C2(C#N)CC2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05652271,CN(C)CCCSCC(=O)C1(c2ccc(Cl)c(Cl)c2)CCC1>>CN(C)CCCSCC(O)C1(c2ccc(Cl)c(Cl)c2)CCC1,,CO,O,CCO,[BH4-].[Na+],test
US20140323470A1,CCOC(=O)c1cccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)c1.CN1CCC[C@H]1c1nnc2ccc(O[C@@H]3CC[C@H](N)c4ccccc43)cn12>>CCOC(=O)c1cccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc([C@@H]5CCCN5C)n4c3)c3ccccc32)c1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20090076078A1,CC(C)OC(=O)Cl.CC1(N2CCC(N3C(=O)N[C@@H]4CCCC[C@@H]43)CC2)CCNCC1>>CC(C)OC(=O)N1CCC(C)(N2CCC(N3C(=O)N[C@@H]4CCCC[C@@H]43)CC2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160272617A1,O=C(O)C(F)(F)C(F)(F)c1n[nH]c(-c2ccc([N+](=O)[O-])cc2)n1>>Nc1ccc(-c2nc(C(F)(F)C(F)(F)C(=O)O)n[nH]2)cc1,[Pd],CO,,O=C[O-].[NH4+],,test
US20100093774A1,Cc1cccc(C(=O)O)c1.Cc1nc2cccc(CN)c2c(=O)n1C1CCC(=O)NC1=O>>Cc1cccc(C(=O)NCc2cccc3nc(C)n(C4CCC(=O)NC4=O)c(=O)c23)c1,,CN(C)C=O,,Cl,O=C(n1ccnc1)n1ccnc1,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4c(F)cccc4F)nc(Cl)c3n2)cc1.COc1ccc(N)cc1OC>>COc1ccc(Nc2nc(-c3c(F)cccc3F)nc3cn[nH]c23)cc1OC,C1COCCO1,CO,,Cl,,test
US05665856,OCCCBr.Oc1ccc(-c2ccc(OC(F)(F)F)cc2)cc1>>OCCCOc1ccc(-c2ccc(OC(F)(F)F)cc2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140349998A1,C=C(CN)C(=O)Nc1cccc(-c2ncnc3[nH]cc(C(=O)OCC)c23)c1.CS(=O)(=O)Cl>>C=C(CNS(C)(=O)=O)C(=O)Nc1cccc(-c2ncnc3[nH]cc(C(=O)OCC)c23)c1,,ClCCl,,CCN(CC)CC,,test
US20020082250A1,COC(=O)CCCO[C@@H]1NC(=O)[C@H]1N.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)CCCO[C@@H]1NC(=O)[C@H]1NC(c1ccccc1)(c1ccccc1)c1ccccc1,,ClCCl,O,CCN(C(C)C)C(C)C,,test
US20070197789A1,COCCOCCl.OCCc1cccs1>>COCCOCOCCc1cccs1,,ClCCl,,CC(C)NC(C)C,,test
US20130116234A1,C1CCNC1.CC(C)c1cccc(-c2c(C(=O)OC(C)(C)C)c(OS(=O)(=O)C(F)(F)F)nc3ccc(Cl)cc23)c1>>CC(C)c1cccc(-c2c(C(=O)OC(C)(C)C)c(N3CCCC3)nc3ccc(Cl)cc23)c1,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20140221344A1,Fc1cccc(F)c1-c1ccc2cnc(Nc3cnccc3Cl)n2n1.OB(O)c1ccc(O)nc1>>O=c1ccc(-c2ccncc2Nc2ncc3ccc(-c4c(F)cccc4F)nn23)c[nH]1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20060089370A1,CO.O=C(O)c1ccc(O)cn1>>COC(=O)c1ccc(O)cn1,,ClCCl,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20150005289A1,CCOC(=O)c1cc2c(N(C)C)nc(C)cn2n1.CCOC(C)=O>>CCOC(=O)CC(=O)c1cc2c(N(C)C)nc(C)cn2n1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20040044030A1,COc1ccc2c(=O)n(C)c(C)c(-c3ccccc3)c2c1.O=C1CCC(=O)N1Br>>COc1ccc2c(=O)n(C)c(CBr)c(-c3ccccc3)c2c1,,ClC(Cl)(Cl)Cl,,,,test
US20140350007A1,CCOc1cc(CN2CCOCC2)cc2[nH]c(=O)c3c(c12)NCCC3.[Cl-].[Cl-]>>CCOc1cc(CN2CCOCC2)cc2[nH]c(=O)c3c(c12)NCCC3.[Cl-].[Cl-],,O,,O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3,,test
US20030018034A1,CC(=O)N1CCNCC1.O=[N+]([O-])c1cc(F)ccc1F>>CC(=O)N1CCN(c2ccc(F)cc2[N+](=O)[O-])CC1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US05053415,C=CCBr.COC(=O)CC(=O)c1cccnc1>>C=CCC(C(=O)OC)C(=O)c1cccnc1,,CO,,[Na],,test
US20030216373A1,CSc1ccc(N2C[C@H](COS(C)(=O)=O)OC2=O)cc1.c1c[nH]cn1>>CSc1ccc(N2C[C@H](Cn3ccnc3)OC2=O)cc1,,CN(C)C=O,O,[H-].[Na+],,test
US20100222325A1,COC(OC)N(C)C.Cc1cc(N(C)C)cc(F)c1C(N)=O>>Cc1cc(N(C)C)cc(F)c1C(=O)/N=C/N(C)C,,C1CCOC1,,,,test
US05096899,CC(C)(C)SC1CC(=O)N1C(C(=O)OCc1ccc([N+](=O)[O-])cc1)C(=O)C(C)(C)CCl.Cn1nnnc1S>>Cn1nnnc1SCC(C)(C)C(=O)C(C(=O)OCc1ccc([N+](=O)[O-])cc1)N1C(=O)CC1SC(C)(C)C,,CN(C)C=O,,,,test
US20100179139A1,CC(C)(C)c1cc2c(-c3ccc(S(=O)(=O)N4CCCC4)nc3)ccnc2[nH]1.Cl>>CC(C)(C)c1cc2c(-c3ccc(S(=O)(=O)N4CCCC4)nc3)ccnc2[nH]1.Cl,,C1COCCO1,CO,,,test
US20140275011A1,NCc1cccc(F)c1.Nc1ncc(Br)nc1Br>>Nc1ncc(Br)nc1NCc1cccc(F)c1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20110086834A1,CC1(C)CNc2cc(Br)ccc21.COCCOc1ccc(Nc2ncnc(Cl)n2)cc1>>COCCOc1ccc(Nc2ncnc(N3CC(C)(C)c4ccc(Br)cc43)n2)cc1,,Cl,,[Na+].[OH-],,test
US20100190688A1,CC(C(=O)NC(CCCCNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N1CSCC1C(=O)NC1CCCc2ccccc21)N(C)C(=O)OC(C)(C)C>>CC(C(=O)NC(CCCCN)C(=O)N1CSCC1C(=O)NC1CCCc2ccccc21)N(C)C(=O)OC(C)(C)C,,CN(C)C=O,,CCNCC,,test
US20100261740A1,COc1cc2ncnc(-c3nnn[nH]3)c2cc1OC.ClCc1ccccn1>>COc1cc2ncnc(-c3nnnn3Cc3ccccn3)c2cc1OC,,CC(=O)N(C)C,,CCN(CC)CC,Cl,test
US20070043066A1,CCOC(=O)CCC(NC(=O)c1ccc(Nc2ncccn2)cc1)C(=O)OCC>>O=C(O)CC[C@H](NC(=O)c1ccc(Nc2ncccn2)cc1)C(=O)O,,C1CCOC1,,CO,[Na+].[OH-],test
US20100173909A1,CCOC(=O)c1sc(N2CC[C@H](NC(=O)c3[nH]c(C)c(Cl)c3Cl)[C@H](OC)C2)nc1-c1cnc(Cl)cn1.CN1CCNCC1>>CCOC(=O)c1sc(N2CC[C@H](NC(=O)c3[nH]c(C)c(Cl)c3Cl)[C@H](OC)C2)nc1-c1cnc(N2CCN(C)CC2)cn1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,O,test
US20130045999A1,CCOC(=O)c1nc(-c2ccc(F)c(Cl)c2)cs1.O=C1CCC(=O)N1Br>>CCOC(=O)c1nc(-c2ccc(F)c(Cl)c2)c(Br)s1,Cl[Fe](Cl)Cl,ClCCl,,,,test
US04940710,C#CC1CN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CCN1.C=O>>C#CC1CN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CCN1C,,O=CO,,,,test
US05378690,CC[C@H](C)[C@@H](CO)NC(=O)OC(C)(C)C>>CC(C)C[C@@H](C=O)NC(=O)OC(C)(C)C,,CS(C)=O,,CCN(CC)CC,,test
US20160264567A1,O=C1c2ccccc2C(=O)N1Cc1cc(-c2cnc(C(F)(F)F)c(F)c2)c(F)cn1>>NCc1cc(-c2cnc(C(F)(F)F)c(F)c2)c(F)cn1,,CO,,NN,O,test
US20110166158A1,Fc1cc(Cl)cc(Br)c1.Oc1cncnc1>>Clc1cc(Br)cc(Oc2cncnc2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100234421A1,CCS.Cc1c(N2C(=O)c3ccccc3C2=O)c(Cl)nc2ccccc12>>CCSc1nc2ccccc2c(C)c1N1C(=O)c2ccccc2C1=O,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20060148858A1,CC(C)(C(=O)O)c1cccc(OCc2ccccc2)c1.CI>>COC(=O)C(C)(C)c1cccc(OCc2ccccc2)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20120283264A1,C[Si](C)(C)C#Cc1cnc(F)c([C@H]2NC(=O)O[C@@H]2c2cccc(F)c2)c1>>C#Cc1cnc(F)c([C@H]2NC(=O)O[C@@H]2c2cccc(F)c2)c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04256748,CCOC(=O)[C@H](C)N.O=[N+]([O-])c1cccc(Cl)c1CBr>>CCOC(=O)[C@H](C)NCc1c(Cl)cccc1[N+](=O)[O-],,CCO,,CCN(CC)CC,Cl,test
US20120252805A1,Cc1cc(NS(=O)(=O)c2cccc(Cl)c2)c2c(C)c(Br)sc2n1.OB(O)c1cncc2ccccc12>>Cc1cc(NS(=O)(=O)c2cccc(Cl)c2)c2c(C)c(-c3cncc4ccccc34)sc2n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20040058964A1,COC(=O)c1cccc(-n2c(C)cc(OCc3ccc(F)cc3F)c(Cl)c2=O)c1>>Cc1cc(OCc2ccc(F)cc2F)c(Cl)c(=O)n1-c1cccc(C(=O)O)c1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20090186870A1,NC(=O)c1cc(F)ccc1Cl.c1cn[nH]c1>>NC(=O)c1cc(-n2cccn2)ccc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20100298349A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.Clc1nc(Cl)c2sccc2n1>>C=C(OCC)c1nc(Cl)nc2ccsc12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US06407116B1,CCOC(=O)Cl.COc1ccc(CNC(=O)c2cccnc2N)cc1.c1ccncc1>>COc1ccc(Cn2c(=O)[nH]c3ccccc3c2=O)cc1,,c1ccncc1,,O,,test
US20070010539A1,CCOC(=O)N1CCC(=O)CC1.CCOP(=O)(CC#N)OCC>>CCOC(=O)N1CCC(=CC#N)CC1,,C1CCOC1,,[H-].[Na+],,test
US20150110732A1,C=COC(C)=O.CC(C)(C)OC(=O)NCCOCCC(=O)O>>C=COC(=O)CCOCCNC(=O)OC(C)(C)C,[Pd],CCOCC,,[K+].[OH-],,test
US20040082629A1,Nc1nc(C(F)(F)F)c(Cl)s1.O=C(Cl)c1ccc(Cl)c([N+](=O)[O-])c1>>O=C(Nc1nc(C(F)(F)F)c(Cl)s1)c1ccc(Cl)c([N+](=O)[O-])c1,,c1ccncc1,,Cl,,test
US20140296225A1,Cc1c(C(=O)CN2CCNCC2=O)ccc(F)c1C#N.Cc1c([C@@H]2CO2)ccc2c1COC2=O>>Cc1c(C(=O)CN2CCN(C[C@H](O)c3ccc4c(c3C)COC4=O)CC2=O)ccc(F)c1C#N,,CCO,,,,test
US20080194629A1,CC=O.COCCCCC1(CNC(=O)[C@H]2C[C@@H](N)CN(C(=O)OCC3c4ccccc4-c4ccccc43)C2)c2ccccc2Oc2ccccc21>>CCN[C@@H]1C[C@H](C(=O)NCC2(CCCCOC)c3ccccc3Oc3ccccc32)CN(C(=O)OCC2c3ccccc3-c3ccccc32)C1,,C1CCOC1,O,[BH3-]C#N.[Na+],,test
US20100210570A1,O=CC(C=O)c1ccc(Br)cc1>>OCC(CO)c1ccc(Br)cc1,,C1CCOC1,,[BH4-].[Na+],,test
US20040266774A1,Nc1cccc(-c2ccnnc2)c1.O=C(O)c1cccc2c1Cc1ccccc1-2>>O=C(Nc1cccc(-c2ccnnc2)c1)c1cccc2c1Cc1ccccc1-2,,ClCCl,c1ccncc1,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US03931195,COc1ccc(C(=O)Nc2ccccc2Cc2ccccn2)cc1>>COc1ccc(C(=O)Nc2ccccc2CC2CCCCN2)cc1,[Pd],CC(=O)O,,,,test
US03987047,CC(=O)N1CCCc2c(c(C)c3ccccc3[n+]2[O-])C1.CC(=O)OC(C)=O>>CC(=O)OC1CCN(C(C)=O)Cc2c1nc1ccccc1c2C,,c1ccccc1,,,,test
US20050209452A1,O=C(O)c1cccc(CBr)c1.O=C1CNCCN1>>O=C1CN(Cc2ccc(C(=O)O)cc2)CCN1,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US06352982B1,O=S(Cl)Cl.OCCCc1ccc(OCc2ccccc2)cc1>>ClCCCc1ccc(OCc2ccccc2)cc1,,Cc1ccccc1,,c1ccncc1,O=C([O-])O.[Na+],test
US20120289549A1,Cc1ccc(S(=O)(=O)Cl)cc1.N[C@H]1C[C@H]2CN(c3ccc(OC(F)(F)F)cc3)C(=O)N2C1>>Cc1ccc(S(=O)(=O)N[C@H]2C[C@H]3CN(c4ccc(OC(F)(F)F)cc4)C(=O)N3C2)cc1,,ClCCl,,CCN(CC)CC,,test
US20160052888A1,COc1ccccc1C=O.O=C1N[C@@]2(CC[C@H](c3ccc4c(c3)CC[C@@H](CS(=O)(=O)c3nnnn3-c3ccccc3)C4)C2)CO1>>COc1ccccc1/C=C/[C@@H]1CCc2cc([C@H]3CC[C@]4(COC(=O)N4)C3)ccc2C1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20080090804A1,CC(=O)Cl.N[C@@H]1CCCN2c3cc(Br)c(F)cc3Oc3cccc(F)c3[C@@H]12>>CC(=O)N[C@@H]1CCCN2c3cc(Br)c(F)cc3Oc3cccc(F)c3[C@@H]12,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20100029650A1,CC(C)OC(=O)N1CCC(COc2ccc(Br)nc2)CC1.NC(=O)CSc1ccc(B(O)O)cc1>>CC(C)OC(=O)N1CCC(COc2ccc(-c3ccc(SCC(N)=O)cc3)nc2)CC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20150291595A1,O=C(Nc1ccccc1)c1c(Br)ccn1S(=O)(=O)c1ccccc1>>O=C(Nc1ccccc1)c1[nH]ccc1Br,,CO,,[Na+].[OH-],,test
US20050049310A1,COC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)c1cc(Br)ccc1O>>COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccccc1O,[Pd],CO,,,,test
US20130131352A1,CC(=O)OC(C)=O.Oc1cc[nH]n1>>CC(=O)n1ccc(O)n1,,c1ccncc1,,,,test
US20090082390A1,CC(C)(C)OC(=O)N1CCN(C(=O)OCC2c3ccccc3-c3ccccc32)C(CC(=O)O)C1.O=C(CBr)c1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCNC(CC(=O)OCC(=O)c2ccc(F)cc2)C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160039803A1,CO.O=C1c2ccccc2C(=O)N1C[C@H]1CN(c2ccc(N3CCOCC3)c(F)c2)C(=O)O1>>CC(=O)NC[C@H]1CN(c2ccc(N3CCOCC3)c(F)c2)C(=O)O1,,O,,NN,,test
US20040266826A1,CN(C)C(OC(C)(C)C)OC(C)(C)C.O=C(O)C[C@]1(c2ccc(Br)s2)CCCCS1(=O)=O>>CC(C)(C)OC(=O)C[C@]1(c2ccc(Br)s2)CCCCS1(=O)=O,,C1CCOC1,,,,test
US05571843,CCOC(=O)C1C(=O)c2ccc(OC(C)=O)cc2C1O>>O=C1CC(=O)c2cc(O)ccc21,,O,,O=S(=O)(O)O,,test
US05196539,CC(=O)OCCBr.c1ccncc1>>CC(=O)OCC[n+]1ccccc1.[Br-],,CC#N,,,,test
US20150197519A1,Cc1cc2c(cc1Br)NC(=O)CO2>>Cc1cc2c(cc1Br)NCCO2,,C1CCOC1,,B,CSC,test
US20120225888A1,COC(=O)C(OC(C)(C)C)c1c(C)nc2c(Cl)c(C)nn2c1-c1cc(F)c2c(c1C)CCCO2>>Cc1nc2c(Cl)c(C)nn2c(-c2cc(F)c3c(c2C)CCCO3)c1C(OC(C)(C)C)C(=O)O,,C1COCCO1,,[Li+].[OH-],,test
US20130203776A1,CC(C)(C)OC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)CC1=O.COc1ccc(F)cc1[Mg]Br>>COc1ccc(F)cc1C(O)C[C@H](CNC(=O)OC(C)(C)C)O[Si](C)(C)C(C)(C)C,,C1CCOC1,CO,[BH4-].[Na+],[Cl-].[NH4+],test
US04284644,Nc1ccc2c(c1)C(=O)C1(CC1)O2.O=C(Cl)OCc1ccccc1>>O=C(Nc1ccc2c(c1)C(=O)C1(CC1)O2)OCc1ccccc1,,c1ccncc1,,,,test
US20140364432A1,Cc1nc(C(=O)N2CCC[C@@H](C)[C@H]2CN)c(-c2ccc(F)cc2)s1.Fc1ccc2oc(Cl)nc2c1>>Cc1nc(C(=O)N2CCC[C@@H](C)[C@H]2CNc2nc3cc(F)ccc3o2)c(-c2ccc(F)cc2)s1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20060041125A1,CCOC(=O)C=[N+]=[N-].O=C(O)c1ccc(C(F)(F)F)nc1Cl>>CCOC(=O)C(=[N+]=[N-])C(=O)c1ccc(C(F)(F)F)nc1Cl,,O=S(Cl)Cl,,,,test
US20130217680A1,C=CC[Sn](CCCC)(CCCC)CCCC.O=C1OCc2cc(Br)cc(F)c21>>C=CCc1cc(F)c2cocc2c1,,Cc1ccccc1,,[Cl-].[Li+],,test
US20150023913A1,CCCC(C)(O)C(=O)OCC>>CCCC(C)(O)C(=O)O,,CO,,[Li+].[OH-],,test
US20040106608A1,CON(C)C(=O)c1ccc2nnn(C)c2c1.Cc1cccc(C)n1>>Cc1cccc(CC(=O)c2ccc3nnn(C)c3c2)n1,,C1CCOC1,,[Li]CCCC,,test
US20070219251A1,CC(C)Oc1ccc(Oc2ncc(-c3ccc(C(C)N4C(=O)c5ccccc5C4=O)cc3)s2)cc1>>CC(C)Oc1ccc(Oc2ncc(-c3ccc(C(C)N)cc3)s2)cc1,,CCO,ClCCl,NN,O,test
US04353827,O=C(O)[C@@H]1CCCN1.O=c1[nH]c2ccc(F)c(Cl)c2c(=O)o1>>O=C1Nc2ccc(F)c(Cl)c2C(=O)N2CCC[C@@H]12,,CN(C)C=O,,O,,test
US20110021434A1,COC(=O)[C@H](CCS(C)=O)NC(=O)OCc1ccccc1>>C=C[C@H](NC(=O)OCc1ccccc1)C(=O)OC,,CCOC(C)=O,,,,test
US20110190334A1,Cc1c(Nc2ccc(I)cc2F)c(N)c2n(c1=O)CCO2.O=S(=O)(Cl)C1CC1COCc1ccccc1>>Cc1c(Nc2ccc(I)cc2F)c(NS(=O)(=O)C2CC2COCc2ccccc2)c2n(c1=O)CCO2,,c1ccncc1,,,,test
US20090012074A1,CCC(=O)N1CCC[C@@H]2Cc3cc(NS(=O)(=O)c4ccc(C(C)C)cc4)ccc3C[C@H]21>>CCCN1CCC[C@@H]2Cc3cc(NS(=O)(=O)c4ccc(C(C)C)cc4)ccc3C[C@H]21,,C1CCOC1,,B,Cl,test
US20160009744A1,N[C@@H]1C[C@H](CO)[C@@H](O)[C@@H]1F.O=C(c1ccc(Cc2cccc(Cl)c2)s1)c1cncnc1Cl>>O=C(c1ccc(Cc2cccc(Cl)c2)s1)c1cncnc1N[C@@H]1C[C@H](CO)[C@@H](O)[C@@H]1F,,CC(C)O,,CCN(C(C)C)C(C)C,Cl,test
US20040259884A1,CCOc1cc(C(F)(F)F)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)Cl.O=S(=O)(N1CCNCC1)N1CCOCC1>>CCOc1cc(C(F)(F)F)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCN(S(=O)(=O)N2CCOCC2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US05439910,CC(=O)c1cc(C(F)(F)F)ccn1.NO>>C/C(=N\O)c1cc(C(F)(F)F)ccn1,,CCO,,O,CC(=O)[O-].[Na+],test
US20160046618A1,C[Si](C)(C)CCOCCl.Cc1cccc([C@]2(C)C=CSC(NC(=O)OC(C)(C)C)=N2)c1F>>Cc1cccc([C@]2(C)C=CSC(N(COCC[Si](C)(C)C)C(=O)OC(C)(C)C)=N2)c1F,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20090111794A1,CC(C)(C)OC(=O)N1CC2CC1CN2Cc1ccc(Cc2nc3ccccc3s2)cc1.Cl.ClCCl>>Cl.Cl.c1ccc2sc(Cc3ccc(CN4C[C@@H]5C[C@H]4CN5)cc3)nc2c1,,ClCCl,,,,test
US05240925,CC1CNCC(C)O1.CCOC(=O)CCCl>>CCOC(=O)CCN1CC(C)OC(C)C1,,Cc1ccccc1,,CCN(CC)CC,,test
US20070066852A1,CCCCCCCC[P+](CCCCCCCC)(CCCCCCCC)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.O=S(=O)([O-])C(F)(F)C(F)F>>CCCCCCCC[P+](CCCCCCCC)(CCCCCCCC)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.O=S(=O)([O-])C(F)(F)C(F)F,,CC(C)=O,,[I-].[K+],,test
US20070167488A1,O=C(O)Cc1ccccc1[N+](=O)[O-]>>O=C1Cc2ccccc2N1O,[Pt],CCO,,CS(C)=O,,test
US20090042874A1,O=C1COc2ccc(O[C@H]3CCNC3)cc2N1>>O=C1COc2ccc(O[C@H]3CCNC3)cc2N1,,CO,,Cl,,test
US20130116234A1,NNC(=O)OCC1c2ccccc2-c2ccccc21.O=C(O)c1c(-c2ccccc2)c2cc(Cl)ccc2[nH]c1=O.O=P(Cl)(Cl)Cl>>O=C(NNC(=O)c1c(Cl)nc2ccc(Cl)cc2c1-c1ccccc1)OCC1c2ccccc2-c2ccccc21,,O,,,,test
US05239075,C1CCNC1.O=C1CCCc2cc(Br)ccc21>>Brc1ccc2c(c1)CCC(N1CCCC1)=C2,,Cc1ccccc1,,,,test
US20060211680A1,Cc1cc(O)c(C(=O)C=Cc2cccc(NC(=O)OC(C)(C)C)c2)c(=O)n1C>>Cc1cc(O)c(C(=O)C=Cc2cccc(N)c2)c(=O)n1C,,ClC(Cl)Cl,,C[Si](C)(C)I,,test
US20080275021A1,CN(C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@@H]1CNC[C@H]1c1ccccc1.COCC1CCC(C(=O)O)CC1>>COCC1CCC(C(=O)N2C[C@@H](c3ccccc3)[C@H](N(C)C(=O)C(C)(C)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)C2)CC1,,C1CCOC1,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20160272634A1,C/C=C/C#N.Nc1n[nH]c2ccnc(OCc3ccccc3)c12>>CC(CC#N)n1nc(N)c2c(OCc3ccccc3)nccc21,,CC#N,,C1CCC2=NCCCN2CC1,,test
US04431263,C#CCN.O=[N+]([O-])c1ccc(F)c([N+](=O)[O-])c1>>C#CCNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-],,CC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100144884A1,C=CCc1ccc(O)c(OC)c1.CCCCS(=O)(=O)Cl>>C=CCc1ccc(OS(=O)(=O)CCCC)c(OC)c1,,ClCCl,,CCN(CC)CC,O,test
US20110021537A1,O=C(NC1CCC1)[C@@H]1CCCN1C(=O)OCc1ccccc1>>O=C(NC1CCC1)[C@@H]1CCCN1,[Pd],CCO,,,,test
US20090306066A1,CC1(C)C(=O)CCN1C(=O)c1ccccc1.CON>>CO/N=C1\CCN(C(=O)c2ccccc2)C1(C)C,,CO,,Cl,CC(=O)[O-].[Na+],test
US20130190378A1,CI.Cc1cc(C(=S)NC[Si](C)(C)C)ccc1Br>>CSC(=NC[Si](C)(C)C)c1ccc(Br)c(C)c1,,C1CCOC1,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20120028961A1,CC(C)(C)NC(=O)c1ccc(C#N)cc1F>>CC(C)(C)NC(=O)c1ccc(CN)cc1F,[Ni],CO,,N,,test
US04294972,CCCCC(C)C(C)(O)CCN.CCOC(=O)Cl>>CCCCC(C)C(C)(O)CCNC(=O)OCC,,CCO,CCO,O,O=C([O-])[O-].[Na+].[Na+],test
US20090093497A1,CI.COC(=O)CCC1CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)C(C)CC1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20030220319A1,CS(=O)(=O)c1cn(CC2=NCCN2)c2ccc([N+](=O)[O-])cc12>>CS(=O)(=O)c1cn(CC2=NCCN2)c2ccc(N)cc12,,CC#N,,,,test
US04061759,CC(=O)Oc1c(C)ncc(CSC(=O)c2ccccc2)c1C(C)O>>C=Cc1c(CSC(=O)c2ccccc2)cnc(C)c1O,,COCCOCCOC,,,,test
US20030229094A1,O=C(CCl)Nc1cccc(Cl)c1.c1ccc(N2CCNCC2)nc1>>O=C(CN1CCN(c2ccccn2)CC1)Nc1cccc(Cl)c1,,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090181966A1,CC(N)=NO.COC(=O)CCCOc1ccc(C(=O)N2c3ccccc3[C@H](N(C(C)=O)c3ccc(Cl)cc3)C[C@@H]2C)cc1>>CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(OCCCc3nc(C)no3)cc2)c2ccccc21,,C1CCOC1,,[H-].[Na+],,test
US20150166480A1,CCOC(=O)c1ccc(-c2ccc(NCC3CCN(CC(C)(C)F)CC3)cc2)cc1F>>CC(C)(F)CN1CCC(CNc2ccc(-c3ccc(C(=O)O)c(F)c3)cc2)CC1,,C1CCOC1,,O,[Li]O,test
US20060025400A1,C1CCNCC1.Cc1ccc(S(=O)(=O)N2C=CNC(=O)C2CC(=O)NCCc2ccc(CCl)cc2)cc1>>Cc1ccc(S(=O)(=O)N2C=CNC(=O)C2CC(=O)NCCc2ccc(CN3CCCCC3)cc2)cc1,,ClCCl,,,,test
US20130059833A1,C/C(=N\O)C(=O)c1ccccc1.O=Cc1ccccc1>>Cc1c(-c2ccccc2)oc(-c2ccccc2)[n+]1[O-],,C1COCCO1,Cl,,,test
US04981853,C1CCNC1.C=C(C)C(=O)Cl>>CC(C)(C=O)N1CCCC1,,CCOCC,,CCN(CC)CC,O,test
US20150166535A1,CC#C[C@@H](CC(=O)OCC)c1ccc(OCc2ccc3nc(Br)nn3c2)cc1.CC(C)c1ccc(B(O)O)cc1>>CC#C[C@@H](CC(=O)OCC)c1ccc(OCc2ccc3nc(-c4ccc(C(C)C)cc4)nn3c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],,test
US20050070479A1,N#Cc1ccc(CN)cc1.O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1>>N#Cc1ccc(C[NH-])cc1.O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1,,C1CCOC1,,CN1CCOCC1,,test
US20110263575A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](O)C1>>CC(C)(C)OC(=O)N[C@@H]1CCC(=O)C1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20090270436A1,COC(=O)c1ccc(-c2cc3ccccc3s2)cc1>>O=C(O)c1ccc(-c2cc3ccccc3s2)cc1,,CO,,Cl,[Na+].[OH-],test
US05378844,CCCn1c(N)c(N)c(=O)n(CCC)c1=O.O=C(NC1(C(=O)O)CCCC1)C(F)(F)F>>CCCn1c(N)c(NC(=O)C2(NC(=O)C(F)(F)F)CCCC2)c(=O)n(CCC)c1=O,,CO,,CC(C)N=C=NC(C)C,,test
US20140275172A1,CCOC(=O)CCc1ccc(OCc2cc(F)cc3cc(C)oc23)c(C)c1C>>Cc1cc2cc(F)cc(COc3ccc(CCC(=O)O)c(C)c3C)c2o1,,O,,C1CCOC1,[Li+].[OH-],test
US20100217012A1,CCO.O=[N+]([O-])c1ccc(OC[C@H]2CO2)c(OCc2ccccc2)c1>>CC(O)[C@@H]1COc2ccc([N+](=O)[O-])cc2O1,[Pd],CN1CCCC1=O,,O=C([O-])O.[Na+],,test
US20100004312A1,Cc1cc(O)cc(C)c1-c1cccc(C=O)c1.Cc1ccc(S(=O)(=O)OCCCS(C)(=O)=O)cc1>>Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(C=O)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080227784A1,CN1CCC(O)CC1.O=[N+]([O-])c1ccc(F)c(F)c1>>CN1CCC(Oc2ccc([N+](=O)[O-])cc2F)CC1,,C1CCOC1,,[H-].[Na+],,test
US20100298295A1,Clc1ncc(Cl)c(Cl)n1.Nc1ncccn1>>Clc1ncc(Cl)c(Nc2ncccn2)n1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20150291595A1,COc1ccc(COC(=O)c2c(Cl)ncnc2Cl)cc1.N>>COc1ccc(COC(=O)c2c(N)ncnc2Cl)cc1,,C1COCCO1,,,,test
US20110003787A1,COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(-c2ccc(Br)n2C(=O)OC(C)(C)C)c1.OB(O)c1cc[nH]n1>>COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(-c2ccc(-c3cc[nH]n3)[nH]2)c1,,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20020160996A1,Cc1c(C)c2c(c(C)c1NC(=O)c1cccs1)C(c1ccc(C(C)C)cc1)C(C)(C)O2>>Cc1c(C)c2c(c(C)c1NCc1cccs1)C(c1ccc(C(C)C)cc1)C(C)(C)O2,,CO,,,,test
US20020094989A1,CCn1nc(Cc2ccccc2)cc1C1CCN(C[C@H]2CN(CC(C)(C)C(=O)OCc3ccc(OC)cc3)C[C@@H]2c2cccc(F)c2)CC1>>CCn1nc(Cc2ccccc2)cc1C1CCN(C[C@H]2CN(CC(C)(C)C(=O)O)C[C@@H]2c2cccc(F)c2)CC1,,O=CO,,,,test
US20150246912A1,CC(C)(CO[Si](C)(C)C(C)(C)C)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C(F)(F)F)cn3)c2)c2cncc(F)c21>>CC(C)(CO)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C(F)(F)F)cn3)c2)c2cncc(F)c21,,C1CCOC1,,,,test
US05859257,CNOC.CSc1ccc(CC(=O)O)cc1>>CON(C)C(=O)Cc1ccc(SC)cc1,,CCOCC,ClCCl,Cl,O=C(n1ccnc1)n1ccnc1,test
US05756857,CC(CO)[C@@H]1CC[C@@H](C)C[C@H]1O.CCI>>CCOCC(C)[C@@H]1CC[C@@H](C)C[C@H]1O,,CN(C)C=O,,O,[H-].[Na+],test
US20120029186A1,O=C1Nc2ccccc2C=Cc2ccccc21>>C1=Cc2ccccc2NCc2ccccc21,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04699651,CCCCON=O.Cc1cnnc2ccccc12>>ON=Cc1cnnc2ccccc12,,CCO,,Cl,,test
US20090203711A1,CC(C)(C)OC(=O)N[C@@H](CCO)C(=O)OC1CCCC1.Nc1c(C(=O)c2ccc(F)cc2F)ccc(=O)n1-c1c(F)cc(O)cc1F>>CC(C)(C)OC(=O)N[C@@H](CCOc1cc(F)c(-n2c(N)c(C(=O)c3ccc(F)cc3F)ccc2=O)c(F)c1)C(=O)OC1CCCC1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150259286A1,COc1c(N)cccc1Br.O=N[O-]>>COc1c(Br)cccc1NN,,Cl,O,Cl[Sn]Cl,,test
US20060084679A1,CC(C)N1CCC(Oc2ccc3nc(C(=O)O)ccc3c2)CC1.COC1CCNCC1>>CC(C)N1CCC(Oc2ccc3nc(C(=O)N4CC=CC4)ccc3c2)CC1,,CN(C)C=O,CO,Cl,O=C(n1ccnc1)n1ccnc1,test
US20070004736A1,C=CC(=O)OC(C)(C)C.CCCN>>CCCNCCC(=O)OC(C)(C)C,,C1CCOC1,,,,test
US04329457,NNc1ccc(Cl)nn1.O=Cc1ccc([N+](=O)[O-])cc1>>O=[N+]([O-])c1ccc(C=NNc2ccc(Cl)nn2)cc1,,O,,CCO,,test
US20100029633A1,COCCOc1ccn2c(-c3cc(C=O)c4cccc(OC)c4n3)cnc2c1.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>COCCOc1ccn2c(-c3cc(-c4cnco4)c4cccc(OC)c4n3)cnc2c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20120165322A1,CC(C)(C)OC(=O)NCc1cccc(C(=O)Nc2nc3c(s2)C[C@@H](N2CCOCC2)CC3)c1>>NCc1cccc(C(=O)Nc2nc3c(s2)C[C@@H](N2CCOCC2)CC3)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040087589A1,CCCC(N)CCC.Cc1cc(C)c(-n2c(C)c(C(=O)CCl)c3c2=NC(C)NC=3Cl)c(C)c1>>CCCC(CCC)NC1=c2c(C(=O)CCl)c(C)n(-c3c(C)cc(C)cc3C)c2=NC(C)N1,,CCOC(C)=O,,CCN(CC)CC,,test
US20120082646A1,COc1c(I)cc(N)cc1C(C)(C)C.O=C=NC(=O)CCl>>COc1c(I)cc(NC(N)=O)cc1C(C)(C)C,,C1COCCO1,,C1CCC2=NCCCN2CC1,,test
US20100021423A1,COc1ncccc1-c1cc(C(=O)c2cccc(N)c2)c(OC)c(C(C)(C)C)c1>>COc1c(C(=O)c2cccc(N)c2)cc(-c2ccc[nH]c2=O)cc1C(C)(C)C,,CC(=O)O,,Br,O=C([O-])O.[Na+],test
US20120071489A1,COC(=O)c1ncoc1C1CCCCC1>>O=C(O)c1ncoc1C1CCCCC1,,CO,,Cl,[Na+].[OH-],test
US20140206681A1,Nc1cc(C(F)(F)F)ccn1.O=C(O)c1ccc(Br)c(OCc2ccccc2)c1>>O=C(Nc1cc(C(F)(F)F)ccn1)c1ccc(Br)c(OCc2ccccc2)c1,CN(C)c1ccncc1,ClCCl,,CN(C)C=O,O=S(Cl)Cl,test
US20140329929A1,CC[Ge](CC)(C(=O)c1ccc(OC)cc1)C(=O)c1ccc(OC)cc1>>CC[Ge](CC)(C(=O)c1ccc(O)cc1)C(=O)c1ccc(O)cc1,,Cc1ccccc1,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20160159814A1,CC(C)(C)[Si](C)(C)Cl.OCc1ccc(C(F)(F)F)cn1>>CC(C)(C)[Si](C)(C)OCc1ccc(C(F)(F)F)cn1,,ClC(Cl)Cl,,c1c[nH]cn1,,test
US20100087427A1,CCN(Cc1ccccc1)C(=O)CCl.COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2N)C(C)C)ccc1OC>>CCN(Cc1ccccc1)C(=O)CN[C@@H]1CNC[C@H]1CN(C(=O)c1ccc(OC)c(OCCCOC)c1)C(C)C,,CC#N,,O,,test
US20070219198A1,C[C@@H]1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc(C#N)cc1Cl.O=S(=O)(O)O>>C[C@@H]1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc(C(N)=O)cc1Cl,,O=C(O)C(F)(F)F,,,,test
US04639529,NCc1ccccc1.O=C1CCCC(=O)O1.O=Cc1ccccc1>>O=C(O)C1CCC(=O)N(Cc2ccccc2)C1c1ccccc1,,Cc1ccccc1C,,,,test
US20160024110A1,CCOC(=O)C(=O)OCC.COc1cc(Br)c(Cl)cc1Cl>>CCOC(=O)C(=O)c1cc(OC)c(Cl)cc1Cl,,C1CCOC1,,CC(C)[Mg]Cl,[Cl-].[NH4+],test
US20080008682A1,COC(=O)c1cccc(CBr)c1.Nc1nc(Cl)nc2nc[nH]c12>>COC(=O)c1cccc(Cn2cnc3c(N)nc(Cl)nc32)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110183985A1,C1CNCCN1.CC(=O)c1cc(F)c2cccnc2c1OS(=O)(=O)C(F)(F)F>>CC(=O)c1cc(F)c2cccnc2c1N1CCNCC1,,C1CCOC1,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],,test
US04420630,O=C(Oc1ccc(S(=O)(=O)Nc2ccccc2)cc1)c1ccc(CCBr)cc1>>C=Cc1ccc(C(=O)Oc2ccc(S(=O)(=O)Nc3ccccc3)cc2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160185752A1,CC(C)N.O=C(c1ccnc(F)c1)N1CCCC(c2ccc(Cl)cc2)C1>>CC(C)Nc1cc(C(=O)N2CCCC(c3ccc(Cl)cc3)C2)ccn1,,CC(C)O,,CCN(CC)CC,,test
US20100179168A1,COc1ccc(NS(=O)(=O)c2ccc(-c3ccc(C)o3)c(F)c2)cc1NC(C)=O>>COc1ccc(NS(=O)(=O)c2ccc(-c3ccc(C)o3)c(F)c2)cc1N,,CCO,,[Na+].[OH-],,test
US06582351B1,COc1ccc(CBr)cc1Cl.N#Cc1cnc2c(c1)[nH]c(=O)n2[C@@H]1CC[C@@H](O)CC1>>COc1ccc(Cn2c(=O)n([C@@H]3CC[C@@H](O)CC3)c3ncc(C#N)cc32)cc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US06265411B1,CC(=O)N1C(=O)Cc2ccccc21.COCCOc1cc2ncnc(Cl)c2cc1OC>>COCCOc1cc2ncnc(C3C(=O)N(C(C)=O)c4ccccc43)c2cc1OC,,CN(C)C=O,,[H-].[Na+],,test
US20090247556A1,CCOC=C(C#N)C(=O)OCC.CS(=O)(=O)c1cccc(NN)c1>>CCOC(=O)c1cnn(-c2cccc(S(C)(=O)=O)c2)c1N,,CCO,,,,test
US04178449,CN(C)C=CC(=O)c1cccc(C(F)(F)F)c1.Nc1nc[nH]c1Br>>FC(F)(F)c1cccc(-c2ccnc3c(Br)ncn23)c1,,CC(=O)O,,,,test
US20120035208A1,COc1ccc(O)cc1OC.Cn1ncc2c(Cl)cc(-c3cccc4[nH]ncc34)nc21>>COc1ccc(Oc2cc(-c3cccc4[nH]ncc34)nc3c2cnn3C)cc1OC,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04851425,O=C(O)C=CCCCc1nn(-c2ccc([N+](=O)[O-])cc2)c2c1CCCC2>>Nc1ccc(-n2nc(CCCCCC(=O)O)c3c2CCCC3)cc1,[Pd],CC(=O)O,,[H][H],,test
US04035376,Cc1cccs1.O=C(Cl)c1ccc(F)cc1>>Cc1ccc(C(=O)c2ccc(F)cc2)s1,,ClCCl,O,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20070299085A1,CC(=O)c1ccc([N+](=O)[O-])c(C)c1.CCOC(=O)C(F)(F)F>>Cc1cc(C(=O)CC(=O)C(F)(F)F)ccc1[N+](=O)[O-],,C1CCOC1,,[H-].[Na+],,test
US20050032838A1,CCSc1cccc(O)c1.COCC(=O)N[C@H]1CC[C@@H](NC(=O)c2cc(F)cnc2Cl)CC1>>CCSc1cccc(Oc2ncc(F)cc2C(=O)N[C@@H]2CC[C@H](NC(=O)COC)CC2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04069038,C=CCNCCCC.O=C(Cl)C(Cl)Cl>>C=CCN(CCCC)C(=O)C(Cl)Cl,,CCN(CC)CC,,Cl,ClCCl,test
US05238599,CCCC1CCC(C(CO)CO)CC1.O=Cc1ccc(Br)c(F)c1>>CCC[C@@H]1CC[C@@H](C2COC(c3ccc(Br)c(F)c3)OC2)CC1,Cc1ccc(S(=O)(=O)O)cc1,ClCCl,,O,,test
US20110263541A1,CCCI.Cc1cc(Cl)nc2cc[nH]c12>>CCCn1ccc2nc(Cl)cc(C)c21,,CN(C)C=O,,O,[H-].[Na+],test
US20080153812A1,COC(=O)c1cnc(N2CCN(C)C(=O)C2)nc1.COc1cc(CCc2cc(N)[nH]n2)cc(OC)c1>>COc1cc(CCc2cc(NC(=O)c3cnc(N4CCN(C)C(=O)C4)nc3)[nH]n2)cc(OC)c1,,CO,Cc1ccccc1,C[Al](C)C,Cl,test
US20100010035A1,CC(=O)O.CCO.CCOCc1cc(Cn2nc(C)c3c(C)nc(CC)cc32)ccc1-c1cc(C)sc1S(=O)(=O)N(COCCOC)c1noc(C)c1C.O=C([O-])O>>CCOCc1cc(Cn2nc(-c3ccccc3)c3c(C)nc(CC)cc32)ccc1-c1cc(C)sc1S(=O)(=O)N(COCCOC)c1noc(C)c1C,,O,,Cl,,test
US20070179183A1,CC1CCCC(C)N1S(=O)(=O)Cl.COC(=O)[C@@H](N)Cc1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1>>COC(=O)[C@H](Cc1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1)NS(=O)(=O)N1C(C)CCCC1C,,C1CCOC1,,CCN(CC)CC,Cl,test
US20100160280A1,CC(=O)Oc1cnc(Cl)c(Br)c1>>Oc1cnc(Cl)c(Br)c1,,C1CCOC1,,[Na+].[OH-],,test
US20060106048A1,CCOC(=O)c1ccc(C2=NC(C)(C)Cc3cc(OCC)c4c(c32)CC(C)(C)O4)cc1NCc1ccccn1>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)O)c(NCc3ccccn3)c1)=NC(C)(C)C2,,CO,,[Na+].[OH-],,test
US20050215784A1,CC1(NC(=O)OCc2ccccc2)CCN(c2cc(C#N)ccn2)CC1>>CC1(N)CCN(c2cc(C#N)ccn2)CC1,[Pd],CC(C)O,,O=C[O-].[NH4+],,test
US20050165185A1,CCOCCOc1ccc(CC[Ge](C)(C)C)cc1.Cl[Sn](Cl)(Cl)Cl>>CCOCCOc1ccc(CC[Ge](C)(C)Cl)cc1,,C[N+](=O)[O-],,,,test
US20030087902A1,CCOC(=O)c1[nH]c2ccccc2c1C=O.COc1cccc(CBr)c1>>CCOC(=O)c1c(C=O)c2ccccc2n1Cc1cccc(OC)c1,,CS(C)=O,,O,[H-].[Na+],test
US07071201B2,CC(=O)OC[C@@H]1CNCC[C@@H]1N1CCc2ccccc21.Fc1ccc(CCBr)cc1>>CC(=O)OC[C@@H]1CN(CCc2ccc(F)cc2)CC[C@@H]1N1CCc2ccccc21,,CN(C)C=O,CO,CCN(CC)CC,O,test
US20160024056A1,CC(C)(C)OC(=O)N1CCC(Cn2ccc3cc(Br)ccc32)CC1.Cl>>Brc1ccc2c(ccn2CC2CCNCC2)c1.Cl,,C1COCCO1,ClCCl,CO,,test
US20130059896A1,CC(=O)CCl.COc1ccc(CNC(=S)N=CN(C)C)c(OC)c1>>COc1ccc(CN2C(C(C)=O)=CSC2N)c(OC)c1,,CC#N,,O,O=C([O-])O.[Na+],test
US20070249585A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)CNC>>CCOC(=O)CN(C)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20150299122A1,CNC(=O)[C@@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)N1C/C=C/c1ccc(-c2ccccc2)cc1>>CNC(=O)[C@@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)N1CCCc1ccc(-c2ccccc2)cc1,[Pd],CO,,,,test
US20120082702A1,NC(=O)c1ccc(Cl)nc1Cl.Nc1ccc(N2CCN(C(=O)OCc3ccccc3)CC2)cc1>>NC(=O)c1ccc(Cl)nc1Nc1ccc(N2CCN(C(=O)OCc3ccccc3)CC2)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20070197620A1,CCOC(OCC)n1ccnc1.CON(C)C(=O)C1CCN(S(=O)(=O)c2ccc(C)cc2)c2ccccc21>>Cc1ccc(S(=O)(=O)N2CCC(C(=O)c3ncc[nH]3)c3ccccc32)cc1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20100305096A1,CC(C)(C)OC(=O)n1ccc2c(Br)ccnc21.CCCC[Sn](CCCC)(CCCC)c1nc(N2CCOCC2)c2sc(CN3CCN(C(C)(C)C(N)=O)CC3)c(C)c2n1>>Cc1c(CN2CCN(C(C)(C)C(N)=O)CC2)sc2c(N3CCOCC3)nc(-c3ccnc4[nH]ccc34)nc12,[Cu]I,Cc1ccccc1,,,,test
US20050143443A1,CCOC(=O)c1cc(CCc2ccc(Cl)cc2)[nH]n1>>O=C(O)c1cc(CCc2ccc(Cl)cc2)[nH]n1,,CO,,[Na+].[OH-],,test
US05580986,CC(=O)OC(C)=O.Cn1nc(-n2nccc2N)c(Cl)c1OC(F)F.O=[N+]([O-])O>>CC(=O)Nc1c([N+](=O)[O-])cnn1-c1nn(C)c(OC(F)F)c1Cl,,CC(=O)O,,,,test
US04243682,COc1ccc2cc(C(O)=CC(C)=O)cc(F)c2c1>>COc1ccc2cc(CCC(C)=O)cc(F)c2c1,[Pd],CC(=O)O,,[H][H],,test
US20150148340A1,CCOC=C(C(=O)NC(=O)OCC)C(=O)OCC.Cn1c(=O)oc2cc(N)ccc21>>CCOC(=O)c1cn(-c2ccc3c(c2)oc(=O)n3C)c(=O)[nH]c1=O,,CCO,,Cl,CC(C)(C)[O-].[K+],test
US20160152616A1,C=C/C=C/CBr.Cc1cc2[nH]c(=O)c(=O)n3c2c(c1C)C(C)(C)CC3>>C=C/C=C/Cn1c(=O)c(=O)n2c3c(c(C)c(C)cc31)C(C)(C)CC2,,CN(C)C=O,,O,[H-].[Na+],test
US20060079697A1,CC(C)(C)[Si](C)(C)Cl.OC[C@@H](O)CCl>>CC(C)(C)[Si](C)(C)OC[C@@H](O)CCl,,CN(C)C=O,,c1c[nH]cn1,,test
US20010041171A1,C=CC(=O)O.C=CC(=O)OCCCC.C=CC(N)=O>>C=CC(=O)O.C=CC(=O)OCCCC.C=CC(N)=O,,C1COCCO1,,,,test
US04810486,COP(=O)(OC)C(CCc1ccccc1)P(=S)(OC)OC>>O=P(O)(O)C(CCc1ccccc1)P(O)(O)=S,,ClC(Cl)Cl,,C[Si](C)(C)Br,,test
US20020169192A1,CCCCCCC(=O)NCCc1cccc(O[Si](C)(C)C(C)(C)C)c1>>CCCCCCCNCCc1cccc(O[Si](C)(C)C(C)(C)C)c1,,C1CCOC1,,B,,test
US20060276655A1,NCC1(CC2CC2)CCC2(CC1)OCCO2.O=C(Cl)c1ccc(Cl)cc1Cl>>O=C(NCC1(CC2CC2)CCC2(CC1)OCCO2)c1ccc(Cl)cc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080021032A1,COC(=O)C1CCC(COS(=O)(=O)c2ccc(C)cc2)CC1.O=[N+]([O-])c1cc[nH]n1>>COC(=O)C1CCC(Cn2ccc([N+](=O)[O-])n2)CC1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US04826815,CC(C)N1CCOC1=O.O=C(Cl)CCc1ccccc1>>CC(C)[C@@H]1COC(=O)N1C(=O)CCc1ccccc1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20130150339A1,COc1cc(Cl)ccc1-c1nccc2cc(S(=O)(=O)Oc3c(F)c(F)c(F)c(F)c3F)ccc12.COc1ccc(CNc2ncns2)c(OC)c1>>COc1cc(Cl)ccc1-c1nccc2cc(S(=O)(=O)Nc3ncns3)ccc12,,C1CCOC1,CCOC(C)=O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20160022626A1,O=C(O)CCNC(=O)OCC1c2ccccc2-c2ccccc21.O=C1CCC(=O)N1O>>O=C(CCNC(=O)OCC1c2ccccc2-c2ccccc21)ON1C(=O)CCC1=O,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04601747,CC1=CC(C)=NC2=NC(=O)NS(=O)(=O)N12.CNOC>>CON(C)S(=O)(=O)NC(=O)Nc1nc(C)cc(C)n1,,ClCCl,,,,test
US04007282,CC(C)(C)c1cc(C(C)(CCC(=O)O)c2ccc(O)c(C(C)(C)C)c2)ccc1O.Cc1ccccc1>>CCCCOC(=O)CCC(C)(c1ccc(O)c(C(C)(C)C)c1)c1ccc(O)c(C(C)(C)C)c1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20160168139A1,O=C(CCl)CCl.O=C([O-])c1ccccc1>>O=C(CCl)COC(=O)c1ccccc1,,CN(C)C=O,,O,,test
US20130005702A1,O=C(NCC(c1ccc(F)cc1)c1ccc(-c2cn[nH]c2)cc1)OCc1ccccc1>>CNCC(c1ccc(F)cc1)c1ccc(-c2cn[nH]c2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080280888A1,COc1cccc2sc(O[C@@H]3CC[C@@H](N)CC3)nc12.O=Cc1ccc2c(c1)NC(=O)CO2>>COc1cccc2sc(O[C@@H]3CC[C@@H](NCc4ccc5c(c4)NC(=O)CO5)CC3)nc12,,CO,ClCCCl,[BH4-].[Na+],,test
US04987132,COc1cc(N)cc(OC)c1OC.O=C(O)C1CSC(c2cccnc2)N1>>COc1cc(NC(=O)C2CSC(c3cccnc3)N2)cc(OC)c1OC,,CCOC(C)=O,CN(C)C=O,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US04208343,N#Cc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]>>N#Cc1ccc(N)cc1N,,CCO,,Cl,,test
US20160031903A1,CC(C)(C)OC(=O)NCC1(C(=O)O)CC1.CCI>>CCN(CC1(C(=O)O)CC1)C(=O)OC(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20100292242A1,CN1Cc2cc(OS(=O)(=O)C(F)(F)F)ccc2C(c2ccc(Cl)c(Cl)c2)C1.N#Cc1ccccc1B(O)O>>CN1Cc2cc(-c3ccccc3C#N)ccc2C(c2ccc(Cl)c(Cl)c2)C1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060199838A1,COc1cc(NC(=O)c2ccc(OC)c([N+](=O)[O-])c2)ccc1NS(C)(=O)=O.CS(=O)(=O)Cl>>COc1ccc(C(=O)Nc2ccc(NS(C)(=O)=O)c(OC)c2)cc1NS(C)(=O)=O,[Pd],CO,c1ccncc1,Cl,ClCCl,test
US06028032,CC(=O)OCC1=C(c2ccccc2)C(=O)N(C(C)(C)C(=O)OCc2ccccc2)CO1>>CC(C)(C(=O)OCc1ccccc1)N1COC(CO)=C(c2ccccc2)C1=O,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US05753657,O=c1[nH]c2c3ccccc3c(=Cc3ccncc3)c2n2ccnc12>>O=c1[nH]c2c(n3ccnc13)C(Cc1ccncc1)c1ccccc1-2,[Pd],CC(=O)O,,CN(C)C=O,,test
US20140256736A1,COc1ccc(CN(c2ncns2)S(=O)(=O)c2cc(F)c(F)cc2F)c(OC)c1.COc1ccc(Cn2cc(-c3cc(Cl)ccc3O)n3cncc3c2=O)cc1>>COc1ccc(Cn2cc(-c3cc(Cl)ccc3Oc3cc(F)c(S(=O)(=O)N(Cc4ccc(OC)cc4OC)c4ncns4)cc3F)n3cncc3c2=O)cc1,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20090247526A1,COc1ccc(CSc2cc(NC(N)=S)ncc2Br)cc1.O=C(CBr)CCc1ccccc1>>COc1ccc(CSc2cc(Nc3nc(CCc4ccccc4)cs3)ncc2Br)cc1,,CCO,,CCN(CC)CC,,test
US04156002,CSC1NC(=O)N(C(C)C)C(=O)N1.NC1CC1>>CC(C)N1C(=O)NC(NC2CC2)NC1=O,,O,,CC(=O)O,,test
US06008237,C=CCBr.Oc1ccc2c(CCc3ccccc3)csc2c1>>C=CCOc1ccc2c(CCc3ccccc3)csc2c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060276453A1,CCOC(=O)c1ccc2cc3n(c2c1)C(C)CNC3=O>>CC1CNC(=O)c2cc3ccc(C(=O)O)cc3n21,,C1CCOC1,CCO,[Na+].[OH-],,test
US20150307532A1,CN(C)C(=N)c1sc(Br)c([Si](C)(C)C)c1C#N>>CN(C)C(=N)c1sc(Br)cc1C#N,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20070213364A1,Cc1cc2ccccc2n1-c1cccc(C2OCCO2)c1>>Cc1cc2ccccc2n1-c1cccc(C=O)c1,,C1CCOC1,,Cl,O,test
US20080280869A1,COC(=O)c1cccc(-c2ncn(-c3ccc(OC)cc3)n2)c1>>COc1ccc(-n2cnc(-c3cccc(C(=O)O)c3)n2)cc1,,C1CCOC1,,[Na+].[OH-],,test
US20090270405A1,COc1ccc(CN)c(OC)c1.COc1ccc2nc(Cl)cnc2c1>>COc1ccc(CNc2cnc3cc(OC)ccc3n2)c(OC)c1,,CS(C)=O,,CCOC(C)=O,,test
US20140121231A1,CC(C)(C)C1Cc2[nH]c(=O)c3ccc(C(N)=O)cc3c2CO1>>CC(C)(C)C1Cc2[nH]c(=O)c3ccc(C#N)cc3c2CO1,,CN1CCCC1=O,,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US20130331378A1,C[Si](C)(C)Cl.c1ccc(-c2cc3ccccn3n2)cc1>>C[Si](C)(C)c1cccc2cc(-c3ccccc3)nn12,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US20130324579A1,COc1ccc2[nH]ccc2c1.O=C(Cl)C(=O)Cl>>COc1ccc2[nH]cc(C(=O)C(=O)Cl)c2c1,,CCOCC,,,,test
US20150291563A1,CS(=O)(=O)Cl.OC(C1=NN(c2cccc(C3=CCNCC3)c2)C(c2ccccc2Cl)C1)(C(F)(F)F)C(F)(F)F>>CS(=O)(=O)N1CC=C(c2cccc(N3N=C(C(O)(C(F)(F)F)C(F)(F)F)CC3c3ccccc3Cl)c2)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20100204196A1,COc1cc2c(cc1[N+](=O)[O-])N(C(=O)CCN(C)C)CC2>>COc1cc2c(cc1N)N(C(=O)CCN(C)C)CC2,Cl[Fe](Cl)Cl,CO,,NN,O,test
US20160009744A1,COc1ccccc1CCc1csc(C(=O)c2cncnc2N[C@@H]2C[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)C2)c1>>COc1ccccc1CCc1csc(C(=O)c2cncnc2N[C@@H]2C[C@H](CO)[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)C2)c1,,CCO,,Cl,,test
US05922871,COC(=O)c1ccc(C(=O)N2CCN(c3ncccc3NC(C)C)CC2)cc1.C[C@H](N)CO>>CC(C)Nc1cccnc1N1CCN(C(=O)c2ccc(C(=O)N[C@@H](C)CO)cc2)CC1,,CO,,O,,test
US20100286118A1,CN1Cc2cc(B3OC(C)(C)C(C)(C)O3)ccc2C1=O>>CN1Cc2cc(B(O)O)ccc2C1=O,,CC(C)=O,,Cl,,test
US04104280,CC(C)CCO.O=C(O)Cc1ccc2c(c1)CCc1ccccc1S2>>CC(C)CCOC(=O)Cc1ccc2c(c1)CCc1ccccc1S2,,CC(C)CCO,,Cl,,test
US20130261129A1,BrCCCBr.Cc1ccc(C)n1C1C=C[C@@H](C(=O)OCc2ccccc2)C1>>Cc1ccc(C)n1[C@@H]1C=C[C@](CCCBr)(C(=O)OCc2ccccc2)C1,,C1CCOC1,,,,test
US20060211698A1,C[Sn](C)(C)N=[N+]=[N-].Cc1nc(C)c(-c2ccc3cc(-c4c(C5CCCCC5)c5ccc(C#N)cc5n4CC(=O)N4CCOCC4)ccc3n2)s1>>Cc1nc(C)c(-c2ccc3cc(-c4c(C5CCCCC5)c5ccc(-c6nnn[nH]6)cc5n4CC(=O)N4CCOCC4)ccc3n2)s1,,CN1CCCC1=O,,,,test
US20070249670A1,Cc1cccc(Cl)c1N=C=O.Nc1cc2ccccc2cc1C(=O)O>>Cc1cccc(Cl)c1NC(=O)Nc1cc2ccccc2cc1C(=O)O,,CS(C)=O,O,,,test
US20070259879A1,Cc1cc(Br)ccc1C(=O)C(=O)N1CCN(C(=O)c2ccccc2)C[C@H]1C.c1cn[nH]c1>>Cc1cc(-n2cccn2)ccc1C(=O)C(=O)N1CCN(C(=O)c2ccccc2)C[C@H]1C,,CCCCCC,CCOC(C)=O,CO,ClC(Cl)Cl,test
US20110224262A1,BrBr.Cc1cc(-c2ccccc2)n[nH]1>>Cc1[nH]nc(-c2ccccc2)c1Br,,ClCCl,,,,test
US20110076291A1,OCCc1ccsc1.Oc1ccc(Cl)nc1I>>Clc1ccc(OCCc2ccsc2)c(I)n1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140113944A1,CC(C)(C)OC(=O)NCC(=O)N[C@@]1(C(=O)O)C[C@H](Sc2nnc[nH]2)[C@@H]2[C@H]1[C@H]2C(=O)O.Cl>>Cl.NCC(=O)N[C@@]1(C(=O)O)C[C@H](Sc2nnc[nH]2)[C@@H]2[C@H]1[C@H]2C(=O)O,,CCOC(C)=O,,,,test
US20070244103A1,CC(C)(C)OC(=O)NCC1CN(Cc2ccccc2)CCO1>>CC(C)(C)OC(=O)NCC1CNCCO1,[Pd],C1CCOC1,CO,,,test
US20130190330A1,O=S(=O)(Cl)c1cccc(Br)c1.O=c1[nH]nc(-c2ccc(Cl)cc2)n1C[C@H](O)C(F)(F)F>>O=c1n(S(=O)(=O)c2cccc(Br)c2)nc(-c2ccc(Cl)cc2)n1C[C@H](O)C(F)(F)F,,C1CCOC1,,O,[H-].[Na+],test
US20110172455A1,CS(=O)(=O)Cl.OCCCc1cccc(C(F)(F)F)c1>>CS(=O)(=O)OCCCc1cccc(C(F)(F)F)c1,,ClCCl,,CCN(CC)CC,,test
US20060069143A1,C=C(c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)c1cccc(C)n1>>Cc1cccc(C(C)c2c[nH]cn2)n1,[Pd],O=C(O)C(F)(F)F,,,,test
US20020128233A1,FC(F)(Br)C(F)(F)Br.c1cc(C2OCCO2)cs1>>Brc1sccc1C1OCCO1,,C1CCOC1,,[Li]CCCC,,test
US20130261111A1,CC(C)(C)OC(=O)N1CC(CO)C(N)(c2ccccc2)C1.O=C(N=C=S)c1ccccc1>>CC(C)(C)OC(=O)N1CC(CO)C(NC(=S)NC(=O)c2ccccc2)(c2ccccc2)C1,,C1CCOC1,,ClCCl,O=C([O-])O.[Na+],test
US20040110945A1,COCCl.O=C1CC[C@H]2CO[C@H](c3ccccc3)N12>>COC[C@@H]1C[C@H]2CO[C@H](c3ccccc3)N2C1=O,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20040167123A1,CC1CCCC(=O)C1.Nn1c(=O)c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2sccc21>>CC1CCCC(=Nn2c(=O)c(C3=NS(=O)(=O)c4ccccc4N3)c(O)c3sccc32)C1,,CC(=O)N(C)C,,,,test
US20090275590A1,C1CCNC1.Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CCN(C(=O)CCl)C2>>Cl.Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CCN(C(=O)CN1CCCC1)C2,,CN(C)C=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20100217012A1,O=C1Cc2c(ccc3c2O[C@@H](CO)CO3)N1>>O=C1Cc2c(ccc3c2O[C@@H](CO)CO3)N1,,c1ccncc1,,O,,test
US20060128783A1,CCOC(=O)c1c(S(=O)(=O)NCCNc2ccc(OC)cc2)c2cc(Br)ccc2n1S(=O)(=O)c1ccccc1.CS(=O)(=O)Cl>>CCOC(=O)c1c(S(=O)(=O)NCCN(c2ccc(OC)cc2)S(C)(=O)=O)c2cc(Br)ccc2n1S(=O)(=O)c1ccccc1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20080004442A1,CC(NC(=O)OC(C)(C)C)C(=O)N1CCS(=O)(=O)CC1>>CC(N)C(=O)N1CCS(=O)(=O)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030105151A1,Cc1c(CCC(=O)O)c[nH]c1C=O.O=C1Cc2cc(Cl)ccc2N1>>Cc1c(CCC(=O)O)c[nH]c1C=C1C(=O)Nc2ccc(Cl)cc21,,CCO,,C1CCNCC1,,test
US20080287479A1,COC(=O)c1cc(C(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c([N+](=O)[O-])cc1F>>COC(=O)c1cc(C(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(N)cc1F,[Ni],C1CCOC1,CO,,,test
US20110015175A1,CI.Cc1nc(C)n(-c2ccc(NC(N)=S)cc2F)n1>>CSC(=N)Nc1ccc(-n2nc(C)nc2C)c(F)c1.I,,CCO,,,,test
US20140275179A1,COC(=O)CCc1cc(F)c(O)c(F)c1.OCc1c(C(F)(F)F)nsc1Br>>COC(=O)CCc1cc(F)c(OCc2c(C(F)(F)F)nsc2Br)c(F)c1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040058894A1,CCCCCCCCI.Oc1ccc(Br)cc1Cl>>CCCCCCCCOc1ccc(Br)cc1Cl,,CC#N,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20030060631A1,CC(C)(C)OC(=O)N[C@@H]1CNCC12CC2.Cc1c(F)c(F)c(N)c2c(=O)c(C(=O)O)cn(C3CC3)c12>>Cc1c(N2C[C@@H](NC(=O)OC(C)(C)C)C3(CC3)C2)c(F)c(N)c2c(=O)c(C(=O)O)cn(C3CC3)c12,,CS(C)=O,,,,test
US04921524,CC(=O)Cl.CCCC(=O)C1=C(O)C(c2ccc(OC)cc2)CCC1=O>>CCCC(=O)C1=C(O)C(c2ccc(O)c(C(C)=O)c2)CCC1=O,,CC(Cl)Cl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US04927838,CCCCCc1c(C=O)oc2cc(OC)ccc12.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCCc1c(/C=C/C(=O)OC)oc2cc(OC)ccc12,,ClCCl,,,,test
US20050009829A1,C1CCNC1.O=C(O)c1ccc([N+](=O)[O-])c(F)c1>>O=C(c1ccc([N+](=O)[O-])c(F)c1)N1CCCC1,CN(C)C=O,ClCCl,c1ccccc1,CCN(CC)CC,O=S(Cl)Cl,test
US04880806,O=C(O)c1cn(C2CC2)c2c(CO)c(N3CCN(Cc4ccccc4)CC3)c(F)cc2c1=O>>O=C(O)c1cn(C2CC2)c2c(CO)c(N3CCNCC3)c(F)cc2c1=O,[Pd],CCO,,,,test
US20110230478A1,CN(C)S(=O)(=O)c1ccc(N)cc1.COCC(C)Nc1nc(Cl)ncc1Cl>>COCC(C)Nc1ccc(S(=O)(=O)N(C)C)cc1Cl,,C1COCCO1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20060211603A1,CC(=O)CC(O)=C1C(=O)OC(C)(C)OC1=O.CCO.NNc1ccccc1>>CCOC(=O)Cc1cc(C)nn1-c1ccccc1,,CCO,CCOC(C)=O,,,test
US05595958,C1CCCCC1.COCCOC.O=Cc1cnccc1Br.[Cl-].[NH4+]>>OC(c1cnccc1Cl)c1cnccc1Br,,C1CCCCC1,,CC(C)[N-]C(C)C.[Li+],,test
US20100267718A1,COc1cc2ncn(Cc3ccccc3)c(=O)c2cc1O.Cc1ccc(S(=O)(=O)OCCCl)cc1>>COc1cc2ncn(Cc3ccccc3)c(=O)c2cc1OCCCl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080176830A1,O=C(Cl)OCc1ccccc1.O=C1CCc2cc(-c3ccc(C(F)(F)F)cc3)ccc2N1>>O=C1CCc2cc(-c3ccc(C(F)(F)F)cc3)ccc2N1C(=O)OCc1ccccc1,,C1CCOC1,,CCOCC,[Li]CCCC,test
US20130310411A1,COc1ccc(S)cc1.Clc1c2ccccc2nc2cccc(Br)c12>>COc1ccc(Sc2c3ccccc3nc3cccc(Br)c23)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20100222345A1,ClC(Cl)(Br)C(Cl)(Cl)Br.Fc1cc(F)cc(C2OCCO2)c1>>Fc1cc(C2OCCO2)cc(F)c1Br,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US05616579,CC(O)=S.O=C(CCl)NC/C=C\COc1cc(CN2CCCCC2)ccn1>>CC(=O)SCC(=O)NC/C=C\COc1cc(CN2CCCCC2)ccn1,,C1CCOC1,,[H-].[Na+],,test
US05444152,CCOC(=O)CCNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OCc1ccccc1>>CCOC(=O)CCNC(=O)[C@H](N)Cc1c[nH]c2ccccc12,[Pd],CO,,[H][H],,test
US20090029978A1,CC(C)(C)OC(=O)c1ccsc1N.O=C=Nc1ccc(Oc2ccccc2)cc1>>CC(C)(C)OC(=O)c1ccsc1NC(=O)Nc1ccc(Oc2ccccc2)cc1,,c1ccncc1,,CC(=O)O,O,test
US20150284405A1,COC(=O)c1c(OC(C)C)ccc2[nH]ccc(=O)c12>>CC(C)Oc1cc2c(=O)cc[nH]c2cc1C(=O)O,,O,,C1CCOC1,[Li+].[OH-],test
US05821239,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCN(CC)C(=O)Oc1cnccc1N>>CCN(CC)C(=O)Oc1cnccc1NC(=O)OC(C)(C)C,,ClCCl,,CCCCCC,,test
US20050054626A1,CC(C)[C@@H]1C[C@H](N(C)C(C)C)CC[C@@H]1NC(=O)CNC(=O)OCc1ccccc1>>CC(C)[C@@H]1C[C@H](N(C)C(C)C)CC[C@@H]1NC(=O)CN,[Pd],CO,,O=C(O)C(F)(F)F,,test
US04837305,CC(=O)CCCCC(=O)O.CCCCN>>CCCCNC(=O)CCCCC(C)=O,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20080027074A1,CC(C)(C)OC(=O)N1CCC(c2ccccc2O)CC1.O=S(=O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCC(c2ccccc2OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)CC1,CN(C)c1ccncc1,ClCCCl,,CCN(C(C)C)C(C)C,,test
US20140228404A1,C#CCBr.O=C(Cn1nc(C(F)F)cc1C(F)F)N1CCC(c2nc(C3=NOC(c4c(F)ccc(O)c4F)C3)cs2)CC1>>C#CCOc1ccc(F)c(C2CC(c3csc(C4CCN(C(=O)Cn5nc(C(F)F)cc5C(F)F)CC4)n3)=NO2)c1F,,CN(C)C=O,O,[I-].[K+],,test
US20140235647A1,Br[Mg]c1ccccc1.O=Cc1cccc(Br)c1F>>OC(c1ccccc1)c1cccc(Br)c1F,,C1CCOC1,,,,test
US05891909,BrCc1ccccc1.COc1ccccc1S(=O)(=O)Oc1cc(C)cc(OCCC=NNC(N)=S)c1>>COc1ccccc1S(=O)(=O)Oc1cc(C)cc(OCCC=NN(Cc2ccccc2)C(=N)S)c1,,C1CCOC1,CO,O=C([O-])O.[Na+],,test
US20160083391A1,CC(=O)NCC(=O)O.NC(=O)c1[nH]nc(C2CCCC2)c1N>>CC(=O)NCC(=O)Nc1c(C2CCCC2)n[nH]c1C(N)=O,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04681952,CC(=O)C(C)(C)C(Br)c1ccc(Cl)cc1>>CC1(C)C(=O)CC1c1ccc(Cl)cc1,,CCO,O,[Na],,test
US06265578B1,C=CCBr.COC(=O)C(C(=O)OC)c1ccc(Oc2ccccc2)cc1>>C=CCC(C(=O)OC)(C(=O)OC)c1ccc(Oc2ccccc2)cc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20060154955A1,O=C1C(NS(=O)(=O)c2ccccc2)Cc2nc(-c3ccccc3)ccc2N1Cc1ccccc1>>O=S(=O)(NC1Cc2nc(-c3ccccc3)ccc2N(Cc2ccccc2)C1)c1ccccc1,,C1CCOC1,,B,CO,test
US20100249229A1,CCC1=C[C@@H]2[C@H](C1)C[C@@]2(CC(=O)OC(C)(C)C)C[N+](=O)[O-]>>CCC1=C[C@@H]2[C@H](C1)C[C@]2(CN)CC(=O)OC(C)(C)C,[Fe],CCO,O,[Cl-].[NH4+],,test
US05739351,CC(C)(C)OC(=O)N1CC2CC(CC#N)CC(O)(c3ccccc3)C2C1>>N#CCC1CC2CNCC2C(O)(c2ccccc2)C1,,C1COCCO1,,Cl,,test
US05459142,BrCc1ccccc1.COC(=O)[C@H](Cc1cc(OC)c(OC)c(OC)c1)NC(=O)C(CC(C)C)=NO>>COC(=O)[C@H](Cc1cc(OC)c(OC)c(OC)c1)NC(=O)C(CC(C)C)=NOCc1ccccc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20120208811A1,CC#N.CCOC(=O)c1cc2ccccc2n1S(=O)(=O)c1ccccc1>>N#CCC(=O)c1cc2ccccc2n1S(=O)(=O)c1ccccc1,,C1CCOC1,O,[Cl-].[NH4+],C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20130281657A1,N[C@@H](Cc1ccc(O)cc1)C(=O)O.Nc1ncc(CO)s1>>Nc1ncc(Cc2cc(C[C@H](N)C(=O)O)ccc2O)s1,,C[N+](=O)[O-],,O=S(=O)(O)C(F)(F)F,,test
US20040063754A1,CCOC(=O)CP(=O)(OCC)OCC>>CCOP(=O)(CC(=O)O)OCC,,CCO,,[Na+].[OH-],,test
US20110257100A1,CCOC(=O)C(C(=O)OCC)C(Nc1ccc(Oc2ccnc3cc(-c4ccc(CN(CCOC)C(=O)OC(C)(C)C)cn4)sc23)c(F)c1)C(F)(F)F>>COCCN(Cc1ccc(-c2cc3nccc(Oc4ccc(NC(C(C(=O)O)C(=O)O)C(F)(F)F)cc4F)c3s2)nc1)C(=O)OC(C)(C)C,,CCO,,,,test
US04035369,Cc1ccc2c(c1)[nH]c(=O)n2CCO.O=S(Cl)Cl>>Cc1ccc2c(c1)[nH]c(=O)n2CCCl,,ClC(Cl)Cl,,,,test
US04339453,CCCCCCCCCCCCN.Clc1ccnc(Cl)n1>>CCCCCCCCCCCCNc1ccnc(Cl)n1,,O,,CCCCO,,test
US04710515,CC(C)(C)c1cc(-c2ccc(N)cc2)cc(C(C)(C)C)c1O.O=C1CCCC(=O)O1>>CC(C)(C)c1cc(-c2ccc(NC(=O)CCCC(=O)O)cc2)cc(C(C)(C)C)c1O,,COCCOC,,O,,test
US05998433,CN(C)Cc1cc2c(o1)CCN(C(=O)c1ccc(C(=O)c3ccc(Cl)c(Cl)c3)cc1)C2.Cl>>CN(C)Cc1cc2c(o1)CCN(C(=O)c1ccc(C(=O)c3ccc(Cl)c(Cl)c3)cc1)C2.Cl,,CCOC(C)=O,CO,,,test
US04927819,O=C1Cc2ccccc2C=Cc2ccccc21.[Li]C>>CC1(O)Cc2ccccc2C=Cc2ccccc21,,CCOCC,,O,,test
US20070149562A1,CC(C)(C)OC(=O)N1C2CCC1CC(Cn1cncn1)(C1CCCCC1)C2>>c1ncn(CC2(C3CCCCC3)CC3CCC(C2)N3)n1,,C1COCCO1,Cl,,,test
US20080139561A1,N[C@@H](CO)c1ccc(F)cc1.O=[N+]([O-])c1cc(F)c(F)nc1F>>O=[N+]([O-])c1cc(F)c(F)nc1N[C@H](CO)c1ccc(F)cc1,,C1CCOC1,,,,test
US05374615,CCOC(C)=O.Cc1ccc2[nH]ccc2c1.c1ccncc1>>CCOC(=O)c1ccccc1-n1ccc2cc(C)ccc21,O=[Cu-],c1ccncc1,,,,test
US20040220208A1,C#CC(=O)OC.O=C(Cc1ncc[nH]1)c1ccccc1>>O=C(c1ccccc1)c1ccc(=O)n2cc[nH]c12,,CO,ClCCl,Cl,O=C([O-])O.[Na+],test
US04748240,NCCCCN1CCN(c2ncccn2)CC1.O=C1OC(=O)C2CCCC1S2>>O=C1C2CCCC(S2)C(=O)N1CCCCN1CCN(c2ncccn2)CC1,,O,,Cc1ccccc1,,test
US09340554B2,CCN(C(=O)OC(C)(C)C)C1CCC(Oc2ncnc3sc4c(c23)CCC4)CC1.Cl>>CCNC1CCC(Oc2ncnc3sc4c(c23)CCC4)CC1.Cl,,CCOCC,,,,test
US20080194629A1,CCNCCC(C)C.COCCCCC1(CNC(=O)[C@H]2C[C@@H](C(=O)O)CN(C(=O)OC(C)(C)C)C2)c2ccccc2Oc2ccccc21>>CCN(CCC(C)C)C(=O)[C@@H]1C[C@H](C(=O)NCC2(CCCCOC)c3ccccc3Oc3ccccc32)CN(C(=O)OC(C)(C)C)C1,,CCN(CC)CC,,Cl,,test
US20090048248A1,Cc1cc(F)ccc1[C@@H]1[C@@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC[C@@H]2CNC[C@H]21.Clc1cnccn1>>Cc1cc(F)ccc1[C@@H]1[C@@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC[C@@H]2CN(c3cnccn3)C[C@H]21,,CO,,CCN(CC)CC,,test
US20060173050A1,CCOc1nc(C(=O)O)cc(N)c1C#N.NCc1ccc(-c2ccccn2)s1>>CCOc1nc(C(=O)NCc2ccc(-c3ccccn3)s2)cc(N)c1C#N,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20100113462A1,CCOC(=O)C1(N)Cc2ccccc2C1.COc1cccc(C(=O)O)c1C>>CCOC(=O)C1(NC(=O)c2cccc(OC)c2C)Cc2ccccc2C1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04970213,CCOC(=O)C(=CN(C)C)C(=O)c1cc2cc(F)c(Cl)cc2nc1Cl.CN(N)C=O>>CCOC(=O)c1cn(N(C)C=O)c2nc3cc(Cl)c(F)cc3cc2c1=O,,CCO,,C1CCC2=NCCCN2CC1,,test
US20080021023A1,CN(CC(=O)O)c1ccc(Cl)c(Cl)c1.CNC(CN1CCCC1)c1cccc(Br)c1>>CN(CC(=O)N(C)C(CN1CCCC1)c1cccc(Br)c1)c1ccc(Cl)c(Cl)c1,,CN(C)C=O,,CCN(CC)CC,O,test
US20050075334A1,COC(=O)c1c(Cl)ccc2[nH]c(SC)nc12.O=S([O-])OO>>COC(=O)c1c(Cl)ccc2[nH]c(S(C)(=O)=O)nc12,,O,,CO,,test
US20120149676A1,CNc1c([N+](=O)[O-])cc(C(=O)N[C@@H]2CC[C@@H](C(F)(F)F)CC2)c(F)c1F.F[C@@H]1CCNC1>>CNc1c([N+](=O)[O-])cc(C(=O)N[C@@H]2CC[C@@H](C(F)(F)F)CC2)c(N2CC[C@@H](F)C2)c1F,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20110201580A1,C=COC(=O)N1C[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)C1.CS(=O)(=O)Cl>>C=COC(=O)N1C[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)COS(C)(=O)=O)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20140142083A1,CI.COC(=O)c1cc(C(F)(F)F)cc(NC2CCCC2)c1C>>COC(=O)c1cc(C(F)(F)F)cc(N(C)C2CCCC2)c1C,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04118561,Clc1nc2ccccc2s1.Nc1nc(N)c2c(ccc3[nH]ccc32)n1>>Nc1nc(N)c2c(ccc3c2ccn3-c2nc3ccccc3s2)n1,,CN(C)C=O,,[H-].[Na+],,test
US05420133,BrP(Br)Br.CCCc1cc(CO)cc(CCC)c1Oc1ccccc1CC(=O)OC>>CCCc1cc(CBr)cc(CCC)c1Oc1ccccc1CC(=O)OC,,ClC(Cl)(Cl)Cl,,Br,,test
US20110065708A1,CC(C(=O)NN)c1c(F)cc2ncccc2c1F.Clc1ccc(Cl)nn1>>CC(c1c(F)cc2ncccc2c1F)c1nnc2ccc(Cl)nn12,,CCCCO,,,,test
US20120245344A1,C=C[Mg]Br.Cc1nc(S(C)(=O)=O)ccc1[N+](=O)[O-]>>Cc1nc(S(C)(=O)=O)cc2cc[nH]c12,,C1CCOC1,,[Cl-].[NH4+],,test
US20100305096A1,CCI.O=S(=O)(c1ccccc1)n1ccc2c(Br)cncc21>>CCc1cc2c(Br)cncc2n1S(=O)(=O)c1ccccc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20120238574A1,Nc1ccc(C2CCNCC2)cc1.OC(c1ccc(CBr)cc1)(C(F)(F)F)C(F)(F)F>>Nc1ccc(C2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US05098602,CCCCCCC(C)C(=O)c1ccc(O)cc1F.CCCCCCCOc1ccc(C(=O)O)cc1F>>CCCCCCCOc1ccc(C(=O)O)c(-c2ccc(C(=O)C(C)CCCCCC)c(F)c2)c1F,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20040191926A1,O=C(O)Cc1ccc(CBr)cc1.OCc1ccccc1>>O=C(Cc1ccc(CBr)cc1)OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CC(C)N=C=NC(C)C,,test
US20090012129A1,CCOC(=O)C(F)P(=O)(OCC)OCC.CNc1cccc(-c2ccc(C=O)cc2)c1>>CCOC(=O)C(F)=Cc1ccc(-c2cccc(NC)c2)cc1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US05026856,Nc1ccc2c(c1)CNC2.O=C(O)c1cn(-c2ccc(F)cc2F)c2c(F)c(F)c(F)cc2c1=O>>Nc1ccc2c(c1)CN(c1c(F)cc3c(=O)c(C(=O)O)cn(-c4ccc(F)cc4F)c3c1F)C2,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US04259337,FC(F)(F)c1cccc(C2CCCNC2)c1>>FC(F)(F)c1cccc(C2CCCNC2)c1,,O,,Cl,[Na+].[OH-],test
US20160176864A1,CS(=O)(=O)c1ccc(F)c2c1[nH]c1cc(Br)cnc12.OCC(F)F>>CS(=O)(=O)c1ccc(OCC(F)F)c2c1[nH]c1cc(Br)cnc12,,CCOC(C)=O,CN1CCCC1=O,CC(C)(C)[O-].[K+],,test
US20010036946A1,CCNCC.CO.O=C(OCC1c2ccccc2-c2ccccc21)N1CCC(n2nc(-c3ccccc3)[nH]c2=O)CC1>>COc1cccc(-c2cn(C3CCNCC3)c(=O)[nH]2)c1,,CO,,C1CCOC1,,test
US05552298,NN.O=C1OC(=O)c2c(O)cccc21>>O=c1[nH][nH]c(=O)c2c(O)cccc12,,CC(=O)O,,,,test
US20080319188A1,C1CN(CC2CCNCC2)C1.O=C(Oc1ccccc1)N(C(=O)Oc1ccccc1)c1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)c(F)c2)ccn1>>O=C(Nc1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)c(F)c2)ccn1)N1CCC(CN2CCC2)CC1,,CN(C)C=O,,Cl,Cl,test
US20130345176A1,CC(=O)OC(C)=O.CC(=O)c1cc2c(O)c3ccccc3c(OC(=O)CNC(=O)OC(C)(C)C)c2o1>>CC(=O)Oc1c2ccccc2c(OC(=O)CNC(=O)OC(C)(C)C)c2oc(C(C)=O)cc12,,CN(C)C=O,,CCOC(C)=O,,test
US20150197511A1,CS(=O)[O-].O=[N+]([O-])c1cc(Br)cc(C(F)(F)F)c1>>CS(=O)(=O)c1cc([N+](=O)[O-])cc(C(F)(F)F)c1,,CS(C)=O,,[Na+].[OH-],,test
US20150087646A1,CC(C)(C)OC(=O)NNc1cc(CNC(=O)C(C)(C)C)ccc1Cl.O=C=NC(=O)c1ccc(CBr)cc1>>CC(C)(C)C(=O)NCc1ccc(Cl)c(-n2nc(-c3ccc(CBr)cc3)[nH]c2=O)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070203157A1,CI.COc1ccc(S(=O)(=O)NC(=O)C2=C(C)N(C(=O)OC(C)(C)C)c3ccnn3C2c2ccc(Cl)c(Cl)c2)cc1>>COc1ccc(S(=O)(=O)N(C)C(=O)C2=C(C)N(C(=O)OC(C)(C)C)c3ccnn3C2c2ccc(Cl)c(Cl)c2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04128540,COC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)OCc1ccccc1.Cl>>COC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO.Cl,[Pd],CO,,,,test
US20120245344A1,CC(C)(C)OC(=O)N1CCC(c2cnc(CO)c(Cl)c2)CC1.O=S(Cl)Cl>>CC(C)(C)OC(=O)N1CCC(c2cnc(CCl)c(Cl)c2)CC1,,ClCCl,,c1ccncc1,,test
US03957833,C#CCOCc1ccc(OCC=C(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>C#CCOCc1ccc(OCC2OC2(C)C)cc1,,ClCCl,,,,test
US20120010135A1,CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)c1cc(F)ccc1O2>>CC(C)(C)OC(=O)N1CCC2(CC1)CC(O)c1cc(F)ccc1O2,,CCO,,[BH4-].[Na+],,test
US20040058978A1,CC(=O)N(C)c1ccc(N)cc1.CCOC(=C1C(=O)N(C(C)=O)c2ccc([N+](=O)[O-])cc21)c1ccccc1>>CC(=O)N(C)c1ccc(N/C(=C2\C(=O)Nc3ccc([N+](=O)[O-])cc32)c2ccccc2)cc1,,CN(C)C=O,CO,[Na+].[OH-],,test
US20040235782A1,NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)[C@@]1(n2cnc3c(=O)[nH]c(N)nc32)O[C@H](CO)[C@@H](O)[C@H]1O>>NCCCC[C@H](N)C(=O)[C@@]1(n2cnc3c(=O)[nH]c(N)nc32)O[C@H](CO)[C@@H](O)[C@H]1O,,c1ccncc1,,C1CCNCC1,,test
US20090105482A1,CC(C)=CC=O.O=C(O)CSc1cnc(NC(=O)N(CCc2ccccc2)C2CCCCC2)s1>>CC(C)=CCN(C(=O)Nc1ncc(SCC(=O)O)s1)[C@@H]1CC[C@@H](C)CC1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,Cl,test
US06903101B1,Clc1ccc(Nc2nnc(Cl)c3ccccc23)cc1.Sc1ccncc1>>Clc1ccc(Nc2nnc(Sc3ccncc3)c3ccccc23)cc1,,CCOC(C)=O,,,,test
US20040132694A1,NC(=O)c1c(Cl)ccc(Nc2c(Cl)c(=O)c2=O)c1O.Nc1ccccc1>>NC(=O)c1c(Cl)ccc(Nc2c(Nc3ccccc3)c(=O)c2=O)c1O,,CS(C)=O,,,,test
US20090062251A1,CNC(=O)CCC[NH2+]C.Cn1c2c(c3cc(C(=O)O)ccc31)CC(C1CCOCC1)CC2>>CNC(=O)CCCN(C)C(=O)c1ccc2c(c1)c1c(n2C)CCC(C2CCOCC2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090312370A1,CCOC(=O)c1cc(C)nc(NN=C(C)C)c1>>CCOC(=O)c1cc(C)nc(N)c1,[Ni],CCO,,[H][H],,test
US20150299189A1,Cn1ccc2cc(Nc3ncc(C4CC4)cc3C(=O)O)cc(/C=C/C3CCCCC3)c21>>Cn1ccc2cc(Nc3ncc(C4CC4)cc3C(=O)O)cc(CCC3CCCCC3)c21,[Pd],CO,,,,test
US20080312208A1,CCc1cnc(-c2cnc(Cl)c(Cl)c2SC)o1.COC(=O)C1CCNCC1>>CCc1cnc(-c2cnc(N3CCC(C(=O)OC)CC3)c(Cl)c2SC)o1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,,test
US20090111819A1,CCn1nc(-c2ccccc2)c(C(C)=O)c([N+](=O)[O-])c1=O.Nc1ccc(C(=O)O)c2ncccc12>>CCn1nc(-c2ccccc2)c(C(C)=O)c(Nc2ccc(C(=O)O)c3ncccc23)c1=O,,CCO,,,,test
US05780482,CCc1ccc([N+](=O)[O-])cn1>>CCc1ccc(N)cn1,[Pd],,,,,test
US06884868B1,CCCOC1CCC(C2CCC(O)CC2)CC1.CS(=O)(=O)Cl>>CCCOC1CCC(C2CCC(OS(C)(=O)=O)CC2)CC1,,ClCCl,,CCN(CC)CC,,test
US05688798,CC(C)(C)OC(=O)N1CCc2cc(-c3ccc(Cl)cc3)ccc2C1.Cl>>Cl.Clc1ccc(-c2ccc3c(c2)CCNC3)cc1,,CCOC(C)=O,,,,test
US07019026B1,CC(C)(C)OC(=O)C(=O)n1ccnc1.CC(C)(C)OC(=O)c1c(N)sc2c1CC(CNC(=O)Cc1ccc3c(c1)OCO3)OC2>>Cc1sc2c(c1C(=O)OC(C)(C)C)C(NC(=O)Cc1ccc3c(c1)OCO3)COC2,,ClCCl,,,,test
US20020156311A1,COC(=O)c1ccc(CN(Cc2ccccc2)c2cccc(N)c2C)cc1.CS(=O)(=O)Cl>>COC(=O)c1ccc(CN(Cc2ccccc2)c2cccc(NS(C)(=O)=O)c2C)cc1,,c1ccncc1,,,,test
US20070191405A1,CC(C)N.O=C(Cl)c1cccc(Br)c1>>CC(C)NC(=O)c1cccc(Br)c1,,ClCCl,,,,test
US20120135990A1,CC(C(=O)NC(C(=O)N1CCC2NCC(COc3ccc(F)c(F)c3)C21)C(C)(C)C)N(C)C(=O)OC(C)(C)C.Clc1ncccn1>>CC(C(=O)NC(C(=O)N1CCC2C1C(COc1ccc(F)c(F)c1)CN2c1ncccn1)C(C)(C)C)N(C)C(=O)OC(C)(C)C,,CN(C)C=O,O,CCN(C(C)C)C(C)C,,test
US20120283216A1,CCOc1ccc2ccc(OC(CC)C(=O)OC)cc2c1>>CCOc1ccc2ccc(OC(CC)C(=O)O)cc2c1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20140200223A1,CCOCC(Cl)Cl.O=C1CCc2ccc(Br)cc21>>O=C1CC2(CCOCC2)c2ccc(Br)cc21,,C1CCOC1,,C[Si](C)(C)Cl,,test
US20090099176A1,COC(=O)c1ccc(Cl)cc1NC(=O)C(C)(C)C>>CC(C)(C)C(=O)Nc1cc(Cl)ccc1CO,,CCO,O,Cl,[BH4-].[Na+],test
US20050272800A1,Cc1ccc(S(=O)(=O)N2CC3CC3(N=C=O)C2c2ccccc2)cc1>>Cc1ccc(S(=O)(=O)N2CC3CC3(N)C2c2ccccc2)cc1,,C1COCCO1,,Cl,,test
US20040224997A1,Nc1ccc(C(F)(F)F)cc1N.S=C=Nc1ccc(Br)cc1>>FC(F)(F)c1ccc2nc(Nc3ccc(Br)cc3)[nH]c2c1,,Cc1ccccc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05539115,CCCCCCCCCCOc1cnc(-c2ccc(C=CCCO)cc2)nc1>>CCCCCCCCCCOc1cnc(-c2ccc(CCCCO)cc2)nc1,[Pd],C1CCOC1,,[H][H],,test
US20020107251A1,O=C(Nc1cccc(-n2c(=O)c(CBr)nc3cccnc32)c1)c1cc(Cl)cc(Cl)c1.c1ccc(-c2ncc[nH]2)cc1>>O=C(Nc1cccc(-n2c(=O)c(Cn3ccnc3-c3ccccc3)nc3cccnc32)c1)c1cc(Cl)cc(Cl)c1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20130059858A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.CC1(C2CCN(c3ncc(C4CC4)cn3)CC2)Cc2cc(Br)ccc2O1>>CC(C)(C)OC(=O)N1CC=C(c2ccc3c(c2)CC(C)(C2CCN(c4ncc(C5CC5)cn4)CC2)O3)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20140094473A1,CC([O-])=S.Cc1ccc(S(=O)(=O)n2cc(-c3cc(N[C@H](COS(C)(=O)=O)C(C)(C)C)c(F)cn3)c3cc(F)cnc32)cc1>>CC(=S)OC[C@@H](Nc1cc(-c2cn(S(=O)(=O)c3ccc(C)cc3)c3ncc(F)cc23)ncc1F)C(C)(C)C,,CN(C)C=O,,O,,test
US06329547B1,CI.O=Cc1ccc(C(=O)O)cc1>>COC(=O)c1ccc(C=O)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20140364396A1,COC(=O)CCC(=O)c1cccc(-c2ccccc2)n1>>O=C(O)CCC(=O)c1cccc(-c2ccccc2)n1,,C1CCOC1,O,[Li]O,,test
US06538152B1,C1N2CN3CN1CN(C2)C3.CCOC(=O)COc1cc(Cl)ccc1OC.O=C(O)C(F)(F)F>>CCOC(=O)COc1cc(Cl)c(C=O)cc1OC,,O=C(O)C(F)(F)F,,O=C([O-])O.[Na+],,test
US03995043,CCNCC.ClCc1nnc2n1-c1ccc(Br)cc1C(c1ccccn1)=NC2>>CCN(CC)Cc1nnc2n1-c1ccc(Br)cc1C(c1ccccn1)=NC2,,CN(C)C=O,,[I-].[Na+],,test
US20130336918A1,COC(=O)CCSCc1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2C(=O)Nc2cnc(-c3cccc(C(F)(F)F)c3)nc2)c1>>O=C(O)CCSCc1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2C(=O)Nc2cnc(-c3cccc(C(F)(F)F)c3)nc2)c1,,C1CCOC1,O,Cl,[Li]O,test
US20060128779A1,Cn1cccc1C=O.N#CCc1ccc(Cl)cc1>>Cn1cccc1/C=C(\C#N)c1ccc(Cl)cc1,,O,,,,test
US20060030613A1,CCOCC.COC(=O)c1ccc(Br)cc1Cl.C[Mg]Br>>CC(C)(O)c1ccc(Br)cc1Cl,,C1CCOC1,,[Cl-].[NH4+],,test
US20070232814A1,CN(C)CC/C=C1/c2ccccc2COc2ccc(CC(=O)O)cc21.Cl>>CN(C)CC/C=C1/c2ccccc2COc2ccc(CC(=O)O)cc21.Cl,,CC(C)=O,,,,test
US20090203663A1,COC(=O)[C@H](Cc1ccc(OC2CCNCC2)cc1)NC(=O)c1c(Cl)cccc1Cl.CS(=O)(=O)Cl>>CS(=O)(=O)N1CCC(Oc2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)CC1,CN(C)c1ccncc1,c1ccncc1,,,,test
US04198527,C=C(C)COc1ccc(Cl)cc1>>CC(C)=COc1ccc(Cl)cc1,,O,,CC(C)(C)[O-].[K+],,test
US20100286129A1,CC(=O)OC(C)=O.CCC(=O)c1ccc(N)cc1>>CCC(=O)c1ccc(NC(C)=O)cc1,,Cc1ccccc1,,,,test
US20070270383A1,CC(C)(CCO)COP(=O)(OC(C)(C)C)OC(C)(C)C.O=C(O)CC(O)(CC(=O)O)C(=O)O>>CC(C)(COP(=O)(OC(C)(C)C)OC(C)(C)C)CC(=O)O,,CN(C)C=O,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20150011528A1,CCOC(C)=O.CN(C)c1ccccn1.Cc1ccc(C(=O)Cl)cc1.Nc1nc2ccc(O)cc2s1>>Cc1ccc(C(=O)N=c2[nH]c3ccc(OC(=O)c4ccc(C)cc4)cc3s2)cc1,,CCOC(C)=O,,C1CCOC1,CCN(CC)CC,test
US20010018525A1,COC(=O)c1ccc(O)cc1O.O=C(NCCCCCCCCc1ccccc1)c1cc(Br)c(OCCO)c(-c2cccc(C(F)(F)F)c2)c1>>COC(=O)c1ccc(OCCOc2c(Br)cc(C(=O)NCCCCCCCCc3ccccc3)cc2-c2cccc(C(F)(F)F)c2)cc1O,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110003787A1,COC[C@H](C)Oc1cc(O)cc(-c2ccc(C3=N[C@H](C)[C@H](C)O3)[nH]2)c1.CS(=O)(=O)c1cnc(Cl)cn1>>COC[C@H](C)Oc1cc(Oc2cnc(S(C)(=O)=O)cn2)cc(-c2ccc(C3=N[C@H](C)[C@H](C)O3)[nH]2)c1,,CC#N,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US04929622,BrCC1CC1.CC1C2CC3CC4=C(C=CCNC1(C)C4)C=C3N2>>CC1C2NC3=CC4=C(CC3C2CC2CC2)CC1(C)NCC=C4,,CCOC(C)=O,O,CCN(C(C)C)C(C)C,CN(C)C=O,test
US20050256105A1,C=CCBr.C=CCCN(NC(=O)OCc1ccccc1)C(=O)OC(C)(C)C>>C=CCCN(C(=O)OC(C)(C)C)N(CC=C)C(=O)OCc1ccccc1,,CN(C)C=O,,,,test
US20110313151A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CC=O)CC1.c1cc2occc2c(N2CCNCC2)n1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CCN2CCN(c3nccc4occc34)CC2)CC1,,CO,ClCCCl,O=C([O-])O.[Na+],,test
US05322847,CC(C)(C)[Si](C)(C)OCc1cccc(C=O)c1.CC1N=Cc2cc(Cl)ccc2S1>>CC(C)(C)[Si](C)(C)OCc1cccc(/C=C/C2N=Cc3cc(Cl)ccc3S2)c1,C1CCNCC1,CCOC(C)=O,c1ccccc1,,,test
US20080194617A1,CCOC(=O)/C=C/c1c(C)nn(C)c1-n1ccc2ccc(O)cc21.COCCBr>>CCOC(=O)/C=C/c1c(C)nn(C)c1-n1ccc2ccc(OCCOC)cc21,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US05872138,BrCc1ccc(OC(CCc2ccccc2)c2ccccc2)cc1.Nc1ccncc1>>Nc1cc[n+](Cc2ccc(OC(CCc3ccccc3)c3ccccc3)cc2)cc1.[Br-],,CC#N,,,,test
US07087626B2,NN.O=C(Cc1ccnc2ccccc12)c1cccc(C(F)(F)F)c1>>NN=C(Cc1ccnc2ccccc12)c1cccc(C(F)(F)F)c1,,CCO,,Cl,,test
US20070213341A1,CCC(=O)C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12.CC[Mg]Cl>>CCC(O)(CC)C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12,,C1CCOC1,,[Cl-].[NH4+],,test
US20110021537A1,CC(=O)CO.O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1>>CC(=O)COC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20040092559A1,N#Cc1ccc(N2C(=O)N3CC[C@H](O)[C@@H]3C2O)c2ccccc12>>N#Cc1ccc(N2C[C@H]3[C@@H](O)CCN3C2=O)c2ccccc12,,CCCCCC,,CC(C)O,,test
US20030195230A1,C1COCCN1.CC(C)(CC=O)c1ccc([N+](=O)[O-])cc1>>CC(C)(CCN1CCOCC1)c1ccc(N)cc1,[Zn],C1CCOC1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20110178060A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C1(CN)CCOCC1>>CCOC(=O)C1(CNC(=O)OC(C)(C)C)CCOCC1,,ClCCl,,O,,test
US20030153596A1,CC(C)(C)C(=O)Nc1cccc(CN2C(=O)c3ccccc3C2=O)n1>>Nc1cccc(CN2C(=O)c3ccccc3C2=O)n1,,CCO,,,,test
US20150216172A1,BrBr.O=Cc1ccc2ncccc2c1>>O=Cc1ccc2ncc(Br)cc2c1,,c1ccncc1,,,,test
US20040151687A1,C=CCC(N)CC=C.CCCCCCCCCCCC[N+](C)(C)CCCCl.[Br-]>>C=CCC(CC=C)[NH2+]CCC[N+](C)(C)CCCCCCCCCCCC.[Br-].[Cl-],,CO,,,,test
US20080312226A1,Nc1ccc(NC(=O)OCC(Cl)(Cl)Cl)cn1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>Nc1ccc(NC(=O)N2CCN(c3nc(-c4ccccc4)ns3)CC2)cn1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20100210644A1,COC(=O)Cl.Cn1nc(I)c2cc(N)cnc21>>COC(=O)Nc1cnc2c(c1)c(I)nn2C,,ClCCl,,c1ccncc1,,test
US20110190255A1,CCOC(=O)[C@H]1CCCN(C[C@@H](O)c2ccc(/C(N)=N/O)cc2)C1.O=C(F)c1noc(-c2ccccc2)c1C(F)(F)F>>CCOC(=O)[C@H]1CCCN(C[C@@H](O)c2ccc(-c3noc(-c4noc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1,,CC#N,CCOC(C)=O,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20080032968A1,CN(C)Cc1c(O)c(F)cc2c1ccn2S(=O)(=O)c1ccccc1.COC(OC)N(C)C>>COc1c(F)cc2c(ccn2S(=O)(=O)c2ccccc2)c1CN(C)C,,CN(C)C=O,,O=C(O)C(F)(F)F,,test
US20130116235A1,Cc1cc(Nc2cc(-c3ccnc(N4CCn5c(cc6c5CCCC6)C4=O)c3C=O)cn(C)c2=O)n[nH]1>>Cc1cc(Nc2cc(-c3ccnc(N4CCn5c(cc6c5CCCC6)C4=O)c3CO)cn(C)c2=O)n[nH]1,,C1CCOC1,,O,[Li+].[OH-],test
US20030028034A1,NN.O=C(C=Cc1cccs1)c1ccc(Br)cc1>>Brc1ccc(C2=CC(c3cccs3)NN2)cc1,,CCO,,O,,test
US20090318407A1,CC(=O)N1CCN(c2ccc(Nc3ncc(C(N)=O)c(NCC4CCNCC4)n3)cc2)CC1.CS(=O)(=O)Cl>>CC(=O)N1CCN(c2ccc(Nc3ncc(C(N)=O)c(NCC4CCN(S(C)(=O)=O)CC4)n3)cc2)CC1,,CC#N,,CCN(CC)CC,,test
US06278025B1,CC(C)(C)c1ccc(C=O)cc1.COc1ccc(C(C)=O)cc1>>COc1ccc(C(=O)C=Cc2ccc(C(C)(C)C)cc2)cc1,,CO,,[Na+].[OH-],,test
US20100035908A1,COC(=O)c1ccc(OC)c(OC)c1OCC(=O)OC(C)(C)C>>COC(=O)c1ccc(OC)c(OC)c1OCC(=O)O,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20090181948A1,CSC(SC)=C(C#N)C#N.NCCCN1CCCCC1.NCCN1CCCCC1>>N#CC(C#N)=C(NCCCN1CCCCC1)NCCN1CCCCC1,,C1CCOC1,O,Cl,O=C([O-])O.[Na+],test
US20060211756A1,C=C(C)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1.Fc1ccc(C(Cl)=NNCc2ccccc2)cc1>>CC1(C(=O)Nc2ccc(C#N)c(C(F)(F)F)c2)CC(c2ccc(F)cc2)=NN1Cc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20100305091A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H]1CCCC(F)(F)[C@H]1O>>CC(C)(C)OC(=O)N[C@@H]1CCCC(F)(F)[C@H]1O,,ClCCl,,CCN(CC)CC,,test
US20150191465A1,Cc1nc(N)nc(N[C@@H](C)c2nc3ccn(C)c3cc2N2CCC[C@H](N3C(=O)c4ccccc4C3=O)C2)c1C#N>>Cc1nc(N)nc(N[C@@H](C)c2nc3ccn(C)c3cc2N2CCC[C@H](N)C2)c1C#N,,CC#N,CCO,NN,O,test
US05713988,CC(=O)c1cc(N)ccc1S(=O)(=O)Cl.OCCNCCO>>Nc1ccc(S(=O)(=O)N(CCO)CCO)cc1,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20100113539A1,CCCC(CCC)COS(=O)(=O)c1ccc(C)cc1.N#CCC(O)c1cccc(N)c1>>CCCC(CCC)CNc1cccc(C(O)CC#N)c1,,CCO,O,,,test
US08242134B2,CC=O.CC[C@H](NC(=O)c1c(C)n(N)c(=O)c2ccccc12)c1ccccc1>>CCNn1c(C)c(C(=O)N[C@@H](CC)c2ccccc2)c2ccccc2c1=O,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20080004327A1,CN(C)C=O.Cc1ccoc1C(=O)O>>Cc1cc(C=O)oc1C(=O)O,,C1CCOC1,,[Li]CCCC,,test
US06420364B1,CC(C)(C)CC(NC(=O)N1CCOCC1)C(=O)NC1(C#N)CCNCC1.O=C(Cl)N1CCOCC1>>O=C(O)N1CCOCC1,,ClCCl,,CN1CCOCC1,Cl,test
US20100113539A1,CCCN(CCC)C(=O)Nc1cccc(C#CCNC(=O)OC(C)(C)C)c1>>CCCN(CCC)C(=O)Nc1cccc(CCCNC(=O)OC(C)(C)C)c1,[Pd],CCO,,,,test
US20130116216A1,CNC.O=C(Cl)C1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CC1>>CN(C)C(=O)C1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110118235A1,CCCN(CCC)C(=O)C1=Cc2ccc(Br)cc2N=C(N)C1.COC(=O)c1ccc(B(O)O)cc1>>CCCN(CCC)C(=O)C1=Cc2ccc(-c3ccc(C(=O)OC)cc3)cc2N=C(N)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20030027840A1,CCCCC12CCC(=O)C(C)=C1c1ccc(O)cc1C2.COCCl>>CCCCC12CCC(=O)C(C)=C1c1ccc(OCOC)cc1C2,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20080139561A1,C1COCCN1.C[C@H](Nc1nc(Nc2cc(C3CC3)[nH]n2)c(F)cc1C=O)c1ccc(F)cc1>>C[C@H](Nc1nc(Nc2cc(C3CC3)[nH]n2)c(F)cc1CN1CCOCC1)c1ccc(F)cc1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20020151750A1,CCOC(=O)C(F)(F)F.CCOc1ccc(C[C@H](N)C(=O)O)cc1>>CCOc1ccc(C[C@H](NC(=O)C(F)(F)F)C(=O)O)cc1,,CO,,CN(C)C(=N)N(C)C,,test
US05281742,CC#N.Cc1ccc(S(=O)(=O)OC2CCCC2)cc1.O=C1COC(=O)N1c1cc(O)c(Cl)cc1F>>CC(C)=C1OC(=O)N(c2cc(OC3CCCC3)c(Cl)cc2F)C1=O,,O,,O=C([O-])[O-].[K+].[K+],,test
US20050080074A1,CCC(CC)c1cc2c(c(C(F)(F)F)c1)C(=O)N1CCN(C(=O)OC(C)(C)C)C[C@@H]21.Cl>>CCC(CC)c1cc2c(c(C(F)(F)F)c1)C(=O)N1CCNC[C@@H]21.Cl,,CCOCC,O,,,test
US20160002215A1,CO/C=C/C(=O)/C=C(\O)C(C)(C)C(F)(F)F>>CC(C)(c1cc(=O)cco1)C(F)(F)F,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US05472964,CC(=O)Nc1cccnc1Cl.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>Cc1nc2cccnc2s1,,C1CCOC1,,[Na+].[OH-],,test
US06326359B1,CN1CCC(O)CC1.COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(COS(C)(=O)=O)nc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C>>COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(COC4CCN(C)CC4)nc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20150361029A1,COC(Cl)Cl.Cc1cc(OC2CCC(C(C)(C)C)CC2)cc2ccccc12>>Cc1cc(O[C@@H]2CC[C@@H](C(C)(C)C)CC2)c(C=O)c2ccccc12,,ClCCCl,ClCCl,Cl[Sn](Cl)(Cl)Cl,,test
US20090137595A1,COCC(=O)Nc1cn2nc(Oc3cccc(N)c3)ccc2n1.Cc1cc(C(=O)Cl)n(C)n1>>COCC(=O)Nc1cn2nc(Oc3cccc(NC(=O)c4cc(C)nn4C)c3)ccc2n1,,CC(=O)N(C)C,,,,test
US05346691,CCC(CC)CO.O=C(O)c1ccc([N+](=O)[O-])cc1>>CCC(CC)COC(=O)c1ccc([N+](=O)[O-])cc1,Cc1ccc(S(=O)(=O)O)cc1,,,,,test
US04287203,CC(S)C(=O)N1CSCC1C(=O)O>>CC1SC(=O)C2CSCN2C1=O,,O,,,,test
US20130150341A1,O=C(Cn1nc(-c2ccc(F)cc2)nc1-c1ccc(F)cc1)N1CCNCC1.S=C=NCCCBr>>O=C(Cn1nc(-c2ccc(F)cc2)nc1-c1ccc(F)cc1)N1CCN(C2=NCCCS2)CC1,,ClC(Cl)Cl,,O=C([O-])[O-].[Na+].[Na+],,test
US20080188531A1,C1CC2(CCN1)OCCO2.CC(=O)Nc1nc(C)c(-c2csc(C(=O)Cl)n2)s1>>CC(=O)Nc1nc(C)c(-c2csc(C(=O)N3CCC4(CC3)OCCO4)n2)s1,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US20120295863A1,C#CCCCCCC.COc1ccc(CNc2ncnc3c2ncn3[C@@H]2O[C@H](CN=[N+]=[N-])[C@@H](O)[C@H]2O)cc1>>CCCCCCc1cn(C[C@H]2O[C@@H](n3cnc4c(NCc5ccc(OC)cc5)ncnc43)[C@H](O)[C@@H]2O)nn1,,CC(C)(C)O,O,O=C(CO)O[CH][C@@H](O)CO,C[O-].[Na+],test
US20090247567A1,N#Cc1ccc(O)c(Br)c1.OCCc1ccsc1>>N#Cc1ccc(OCCc2ccsc2)c(Br)c1,,C1CCOC1,CCOCC,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070010520A1,I.Nc1nc(Br)cn2nc(-c3ccco3)nc12>>Nc1nc(I)cn2nc(-c3ccco3)nc12,,CCO,,,,test
US20150023913A1,CCOC(=O)C1CC12CCC2>>O=C(O)C1CC12CCC2,,C1CCOC1,O,[Li+].[OH-],,test
US20040147612A1,CC(C)S(=O)(=O)Cl.COc1ccc2cc(C(C)CN)ccc2c1>>COc1ccc2cc(C(C)CNS(=O)(=O)C(C)C)ccc2c1,,ClCCl,,CCN(CC)CC,,test
US20070191389A1,CCOC(=O)N1NC([Si](C)(C)C)=CN1c1ccccc1>>C[Si](C)(C)C1=CN(c2ccccc2)N(C(=O)O)N1,,C1CCOC1,O,[Li+].[OH-],,test
US20130274241A1,CC(=O)Cl.O=C(c1ccc(-n2cc(-c3n[nH]c4ccc(C5CCNCC5)cc34)nn2)cc1)N1CCOCC1>>CC(=O)N1CCC(c2ccc3[nH]nc(-c4cn(-c5ccc(C(=O)N6CCOCC6)cc5)nn4)c3c2)CC1,,c1ccncc1,,,,test
US20050130941A1,CC(C)(C)OC(=O)NN(CC1CCCCC1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)C(F)(F)F>>CC(C)(C)OC(=O)NN(CC1CCCCC1)C[C@H](O)[C@@H](N)Cc1ccccc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20050096389A1,CC(C)(CCC(=O)O)C(=O)O.CCO.Cc1ccccc1>>CCOC(=O)CCC(C)(C)C(=O)OCC,,O,,O=S(=O)(O)O,,test
US20140364456A1,Fc1ccc(-c2cc3n(n2)CCC3)cc1.O=C1CCC(=O)N1Br>>Fc1ccc(-c2nn3c(c2Br)CCC3)cc1,,ClC(Cl)Cl,O,,,test
US05324747,CCCCCCCCCCNC(=O)c1cc(N)cc(C(=O)NCCCCCCCCCC)c1.O=C([O-])C(Br)Cc1ccccc1>>NCC(=O)OCc1ccccc1,,CC(C)=O,CN(C)C=O,[I-].[K+],O=C([O-])O.[Na+],test
US20160002188A1,C[C@H]1CN(C(=O)c2ccc(-c3ccc4c(c3)ncn4C)cc2F)CCN1C(=O)OC(C)(C)C.Cl>>C[C@H]1CN(C(=O)c2ccc(-c3ccc4c(c3)ncn4C)cc2F)CCN1.Cl,,ClCCl,,,,test
US20150239845A1,CC(C)(C)OC(=O)COc1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)COc1ccc(N)cc1,[Pd],CO,,[H][H],,test
US20060241172A1,CC=Cc1cc(Cl)cc2c1OC(COS(=O)(=O)c1ccc(C)cc1)CO2.O=[Os](=O)(=O)=O>>Cc1ccc(S(=O)(=O)OCC2COc3cc(Cl)cc(C=O)c3O2)cc1,O=[Os](=O)(=O)=O,C1CCOC1,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US04447446,N#CCO.NCc1ccccc1>>N#CCNCc1ccccc1,,CO,,,,test
US04061656,Cc1ccc(CO)s1.[Br-].c1ccc([PH+](c2ccccc2)c2ccccc2)cc1>>Cc1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)s1.[Br-],,CC#N,,,,test
US20110136800A1,O=C(c1ccc2[nH]cnc2c1)N1CCC[C@@H]2c3cc(O)c([N+](=O)[O-])cc3C[C@@H]21>>Nc1cc2c(cc1O)[C@H]1CCCN(C(=O)c3ccc4[nH]cnc4c3)[C@H]1C2,[Pd],CO,,,,test
US20140005213A1,CC(C)(C)N.Cc1ccc2ccc(C(=O)O)c(C3CC3)c2n1>>Cc1ccc2ccc(C(=O)NC(C)(C)C)c(C3CC3)c2n1,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US04971982,CC1(C)C=C(c2ccc(C(=O)OCc3ccccc3)cn2)c2cc(C#N)ccc2O1>>CC1(C)C=C(c2ccc(C(=O)O)cn2)c2cc(C#N)ccc2O1,[Pd],O=CO,,CCCCN(CCCC)CCCC,,test
US04661603,Cc1cc(C(=O)O)cc(C)c1C(=O)c1cc(-n2ccnc2)ccc1Cl>>Cc1cc(C(=O)O)cc(C)c1C(O)c1cc(-n2ccnc2)ccc1Cl,,O,,[Na+].[OH-],,test
US05696143,CCOC(=O)C(F)F.COc1ccc2c(c1)CCCC2=O>>COc1ccc2c(c1)CCC(=C(O)C(F)F)C2=O,,CCOCC,Cl,CO,C[O-].[Na+],test
US20120028953A1,CC(Cl)OC(=O)Cl.Ic1ccc(OC2CN(C(c3ccccc3)c3ccccc3)C2)nc1>>Cl.Ic1ccc(OC2CNC2)nc1,,ClCCl,,CO,,test
US20100197674A1,CCOC(=O)c1nc2cccnc2n(-c2ccccc2)c1=O>>O=C(O)c1nc2cccnc2n(-c2ccccc2)c1=O,,CC(=O)O,,Cl,,test
US20100267634A1,CCOC(=O)CCCN[C@@H](C(=O)OC(C)(C)C)c1ccccc1>>CC(C)(C)OC(=O)[C@H](NCCCC(=O)O)c1ccccc1,,CO,,Cl,[Na+].[OH-],test
US20060052396A1,CC(C)OB(OC(C)C)OC(C)C.CN1CCC(N(C)S(=O)(=O)c2ccc(Br)cc2)C1>>CN1CCC(N(C)S(=O)(=O)c2ccc(B(O)O)cc2)C1,,C1CCOC1,,O,,test
US20060135773A1,N.O=C1c2ccccc2S(=O)(=O)N1Cc1ccccc1>>NC(=O)c1ccccc1S(=O)(=O)NCc1ccccc1,,CO,,,,test
US20070142363A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(Cl)OC(=O)Cl.CCOC(=O)C1=C(c2ccc(OCCO[Si](C)(C)C(C)(C)C)cc2)CC2CN(C(=O)OC(C)(C)C)CC1N2C>>CCOC(=O)C1=C(c2ccc(OCCO)cc2)CC2CN(C(=O)OC(C)(C)C)CC1N2C(=O)OC(C)(C)C,,ClCCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20100137278A1,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.CI>>COC(=O)C1CCN(C(=O)OC(C)(C)C)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090192156A1,CC(C)(C)OC(=O)N1CCC(OCC(=O)N2CCCCC2)CC1>>CC(C)(C)OC(=O)N1CCC(OCCN2CCCCC2)CC1,,C1CCOC1,,,,test
US20110021352A1,CCOc1ccc2cc(C(=O)C3C=NN(CC)C3=O)c(C(F)(F)F)nc2n1>>CCN1N=CC(C(=O)c2cc3ccc(O)nc3nc2C(F)(F)F)C1=O,,CCO,O,Cl,,test
US20140275241A1,COCO[C@@H]1CC[C@@H]2C[C@H]3[C@@H](CC[C@@]4(C)C(C#N)=CC[C@H]34)C[C@H]2C1>>C[C@@]12CC[C@H]3C[C@H]4C[C@H](O)CC[C@@H]4C[C@@H]3[C@H]1CC=C2C#N,,CO,,Cl,,test
US05504082,Cc1c(SCCN2CCOCC2)ccnc1CO.O=S(Cl)Cl>>Cc1c(SCCN2CCOCC2)ccnc1CCl,,ClC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US20100069307A1,CC(C)(C)OCC(NC(=O)c1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1[N+](=O)[O-])C(=O)OC(C)(C)C>>CC(C)(C)OCC(NC(=O)c1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1N)C(=O)OC(C)(C)C,[Pd],CO,,,,test
US20020049242A1,CN(C)C=O.CSc1sc(C(=O)O)c2c1-c1oc(C)nc1CC2>>CSc1sc(C(N)=O)c2c1-c1oc(C)nc1CC2,,C1CCOC1,,O=C(Cl)C(=O)Cl,,test
US20090062293A1,CC(C)(C)CCC(=O)N1CCN(c2cc(C(N)=NO)ccn2)CC1.O=C(Cl)C1CC1>>CC(C)(C)CCC(=O)N1CCN(c2cc(-c3noc(C4CC4)n3)ccn2)CC1,,CCOC(C)=O,c1ccncc1,,,test
US20110183985A1,CC(=O)c1ccc2ccccc2c1Br>>CC(O)c1ccc2ccccc2c1Br,,CO,,[BH4-].[Na+],,test
US05073553,BrCC1CO1.O=c1[nH]c2cc(O)ccc2c2oc3ccccc3c12>>O=c1[nH]c2cc(OCC3CO3)ccc2c2oc3ccccc3c12,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130096174A1,C[C@@H]1CC(C)(C)c2cccc(N)c21.Cc1nn(C)c(C)c1C(=O)Cl>>Cc1nn(C)c(C)c1C(=O)Nc1cccc2c1[C@H](C)CC2(C)C,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20050271584A1,Brc1cn[nH]c1.O=[N+]([O-])c1ccc(F)cc1>>O=[N+]([O-])c1ccc(-n2cc(Br)cn2)cc1,,CS(C)=O,,CC(C)(C)O[K],,test
US20040214837A1,CCNC1(C(N)=O)CCNCC1.Clc1ccc(-c2c3ccnc(Cl)c3nn2-c2ccc(Cl)cc2Cl)cc1>>CCNC1(C(N)=O)CCN(c2nccc3c(-c4ccc(Cl)cc4)n(-c4ccc(Cl)cc4Cl)nc23)CC1,,CCO,,CCN(CC)CC,,test
US20020173655A1,CCCCCCC(=O)Cl.CSCCCCCNc1c(N)cnc2ccccc12>>CCCCCCC(=O)Nc1cnc2ccccc2c1NCCCCCSC,,c1ccncc1,,,,test
US20130274253A1,C[C@H]1Cc2ccccc2N1C(=O)Cc1nc(N2CCOCC2)cc(=O)[nH]1.O=C1CCC(=O)N1Br>>C[C@H]1Cc2ccccc2N1C(=O)Cc1nc(N2CCOCC2)c(Br)c(=O)[nH]1,,ClC(Cl)Cl,,ClCCl,O,test
US20040127574A1,CCOC(=O)CC(=O)c1ccc(F)cc1.Fc1cc(CBr)ccc1C(F)(F)F>>CCOC(=O)C(Cc1ccc(C(F)(F)F)c(F)c1)C(=O)c1ccc(F)cc1,,COCCOC,,O,[H-].[Na+],test
US04330539,CN[C@H]1[C@H](O)C[C@H]2[C@@H]3C[C@@H](Cl)[C@@]4(Cl)C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C.Cl>>CN[C@H]1[C@H](O)C[C@H]2[C@@H]3C[C@@H](Cl)[C@@]4(Cl)C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C.Cl,,CO,ClC(Cl)Cl,CC(C)=O,,test
US20090149456A1,Cc1ccc(-c2nn3ccccc3c2-c2ccnc(Cl)n2)cc1NC(=O)Cc1cccs1.Nc1cccc(CN2CCCC2)c1>>NC1CCc2ccc(Nc3nccc(-c4c(-c5cccc(NC(=O)Cc6cccs6)c5)nn5ccccc45)n3)cc2C1,,CC(C)O,,Cl,,test
US20100292279A1,CC(C)CO.COC(=O)c1ccc(Br)c(O)c1>>COC(=O)c1ccc(Br)c(OCC(C)C)c1,,CC(C)CO,,,,test
US04001422,C1CC2(CCN1)OCCO2.COc1cc2ncnc(Cl)c2cc1OC>>COc1cc2ncnc(N3CCC(=O)CC3)c2cc1OC,,CCO,Cl,CCN(CC)CC,O=C([O-])[O-].[Na+].[Na+],test
US20120142625A1,CC(C)(C)c1ccc(N)c(N)c1.COc1ccc(CNc2ncnc3c2ccn3[C@@H]2C[C@H](CN(CC(C)C)C3CC(CCC(=O)O)C3)[C@H]3OC(C)(C)O[C@H]32)c(OC)c1>>COc1ccc(CNc2ncnc3c2ccn3[C@@H]2C[C@H](CN(CC(C)C)C3CC(CCC(=O)Nc4ccc(C(C)(C)C)cc4N)C3)[C@H]3OC(C)(C)O[C@H]32)c(OC)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20140275027A1,C[Si](C)(C)CCOCCl.Fc1cnc2[nH]cc(I)c2c1Cl>>C[Si](C)(C)CCOCn1cc(I)c2c(Cl)c(F)cnc21,,C1CCOC1,,[H-].[Na+],,test
US06451734B1,CC1(C)OC(=O)CC(=O)O1.O=C(Cl)Cc1cccc(Cl)c1Cl>>COC(=O)CC(=O)Cc1cccc(Cl)c1Cl,,ClCCl,,Cl,c1ccncc1,test
US20160002221A1,CC(=O)c1ccc(Br)cc1>>CC(O)c1ccc(Br)cc1,,CCO,,Cl,[BH4-].[Na+],test
US05554749,CS(=O)(=O)N1CCN(CC(=O)O)CCN(CC(=O)O)CC1>>O=C(O)CN1CCNCCN(CC(=O)O)CC1,,O=S(=O)(O)O,,O,,test
US20060217369A1,N[C@@H]1CCN(Cc2cccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c23)C[C@H]1O>>NC1CCN(Cc2cccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c23)CC1,,CO,,,,test
US20020086901A1,C#C.CC(=O)CCC=C1CCCC1>>C#CC(C)(O)CCC=C1CCCC1,,C1CCOC1,,CC(C)(C)O[K],,test
US20100152418A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@@H](O)[C@H](N)C(=O)OCc1ccccc1>>C[C@@H](O)[C@H](NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1,,CCN(C(C)C)C(C)C,CN(C)C=O,O=C(O)C(=O)O,,test
US20120010191A1,CC(C)(C)OC(=O)N1CCc2cc(N)ccc2C1.Cn1cc(Br)nc(Br)c1=O>>Cn1cc(Br)nc(Nc2ccc3c(c2)CCN(C(=O)OC(C)(C)C)C3)c1=O,,CC(C)O,,CCN(CC)CC,,test
US20100261755A1,COC(=O)c1ccnc(Cc2ccc(F)cc2F)c1>>COC(=O)C1CCNC(Cc2ccc(F)cc2F)C1,O=[Pt]=O,CC(=O)O,,,,test
US20040106642A1,COCCOCCO[C@H]1c2ccn3c(C)c(C)nc3c2N[C@H](c2ccccc2)[C@H]1O.Cc1nc2c3c(ccn2c1C)[C@@H](O)[C@H](O)[C@@H](c1ccccc1)N3>>Cc1nc2c3c(ccn2c1C)[C@@H](OCCO)[C@H](O)[C@@H](c1ccccc1)N3,,COCCO,,O=S(=O)(O)O,[Na+].[OH-],test
US20160016908A1,CC(=O)N1c2ccc(C#N)cc2[C@H](NC(=O)OCc2ccccc2)[C@@H](C)[C@@H]1C1CC1>>CC(=O)N1c2ccc(C#N)cc2C(N)C(C)C1C1CC1,[Pd],CCO,,,,test
US20160102096A1,COC(=O)CCc1cncn1Cc1ccc(F)cc1.N>>NC(=O)CCc1cncn1Cc1ccc(F)cc1,,CO,,,,test
US20110142796A1,CC(C)(C)[Si](C)(C)OCCN1CCN(c2ccc(Nc3ncc4c5ccnc(Cl)c5n(C5CCCC5)c4n3)nc2)CC1>>OCCN1CCN(c2ccc(Nc3ncc4c5ccnc(Cl)c5n(C5CCCC5)c4n3)nc2)CC1,,CO,,Cl,,test
US20160052898A1,Nc1ccc(F)c([N+](=O)[O-])c1.O=C(Cl)c1ccc(-c2ccccc2)cc1>>O=C(Nc1ccc(F)c([N+](=O)[O-])c1)c1ccc(-c2ccccc2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070179173A1,COC(Cl)Cl.COc1cccc2c1N(C)C(=O)CC2>>COc1ccc(C=O)c2c1N(C)C(=O)CC2,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20030186924A1,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.COc1ccc(COC(=O)Cc2ccccc2O)cc1>>COc1ccc(COC(=O)Cc2ccccc2OC(=O)[C@@H](NC(=O)OCc2ccccc2)C(C)C)cc1,,ClCCl,,CN(C)c1ccccn1,,test
US20040167171A1,COc1ccc(C2CCN(c3c(C)c(C)c4c(c3C)C(O)(c3ccccc3)C(C)(C)O4)CC2)cc1OC>>COc1ccc(C2CCN(c3c(C)c(C)c4c(c3C)C(c3ccccc3)C(C)(C)O4)CC2)cc1OC,,CCO,,,,test
US04755535,CCCCCCCCCCCCN1CCC(Br)C(Br)CC1=O>>CCCCCCCCCCCCN1CC=CC=CC1=O,,Cc1ccccc1,,Cc1cccc(C)n1,,test
US04407798,O=CNc1ccnc(C(=NOC2C=CCC2)C(=O)NC2C(=O)N3C(C(=O)[O-])=C(C[n+]4ccccc4)CS[C@H]23)n1>>Nc1ccnc(C(=NOC2C=CCC2)C(=O)NC2C(=O)N3C(C(=O)[O-])=C(C[n+]4ccccc4)CS[C@H]23)n1,,O=C([O-])O,[Na+],,,test
US20100216788A1,COC(=O)c1cccc(Oc2ccc(Nc3ncnc4ccn(CCNC(=O)OC(C)(C)C)c34)cc2Cl)c1>>CC(C)(C)OC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(C(=O)O)c4)c(Cl)c3)c21,,C1CCOC1,,CO,[Na+].[OH-],test
US20150259331A1,CC(=O)c1cc(Br)ccc1N.O=N[O-]>>O=c1cn[nH]c2ccc(Br)cc12,,O,,Cl,,test
US05814648,CC(C)(C)[Si](C)(C)OC[C@H](NC(=O)c1cccc(I)c1)c1ccccc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)[Si](C)(C)OC[C@H](NC(=S)c1cccc(I)c1)c1ccccc1,,COCCOC,,O,,test
US20100280083A1,CC(=O)O.COc1cc(-c2noc(C)n2)c(C=O)cc1OCc1ccccc1.O.[C-]#[N+]C(C)(C)C>>COc1cc(-c2noc(C)n2)c(C(OC(C)=O)C(=O)NC(C)(C)C)cc1OCc1ccccc1,,CCOC(C)=O,,CC#N,,test
US20160145252A1,COC(=O)c1nnc(-c2cnc(Cl)cc2NC(C)C)s1.O[C@@H]1CCNC1>>CC(C)Nc1cc(Cl)ncc1-c1nnc(C(=O)N2CC[C@@H](O)C2)s1,,CO,,,,test
US04214097,C=CC(C)(C)CC(=O)OCC.OCc1ccccc1>>C=CC(C)(C)CC(=O)OCc1ccccc1,,Cc1ccccc1,,C,C[O-].[Na+],test
US20120071460A1,N#Cc1ccc(N)nc1.NO>>NC(=NO)c1ccc(N)nc1,,CCO,,,,test
US04939253,C[C@H]1[C@H](NC(=O)OC(C)(C)C)C(=O)N1OCC(=O)OC1CCCCC1.O=C(O)C(F)(F)F>>CC1[C@H](N)C(=O)N1OCC(=O)OC1CCCCC1.O=C(O)C(F)(F)F,,COc1ccccc1,,,,test
US20060287522A1,O=C(NCc1cccnc1)c1ccc2n1Cc1ccccc1N(C(=O)c1ccc(Cl)nc1)C2.OCc1ccccc1>>O=C(NCc1cccnc1)c1ccc2n1Cc1ccccc1N(C(=O)c1ccc(OCc3ccccc3)nc1)C2,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20080249106A1,COC(=O)[C@@H](Cc1cn([C@@H]2CCOc3cc(CN4CCC(F)CC4)ccc32)nn1)NS(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)N[C@H](Cc2cn([C@@H]3CCOc4cc(CN5CCC(F)CC5)ccc43)nn2)C(=O)O)cc1,,CO,,[Li+].[OH-],,test
US04518713,CCNCc1ccccc1.Cl.Fc1ccc(C2(CCCCl)OCCO2)cc1>>CCN(CCCC1(c2ccc(F)cc2)OCCO1)Cc1ccccc1.Cl,,CN(C)C=O,O,[I-].[K+],,test
US20150299188A1,COC(OC)c1c(Cl)cnc(Br)c1N.Cc1noc(C)c1B1OC(C)(C)C(C)(C)O1>>COC(OC)c1c(Cl)cnc(-c2c(C)noc2C)c1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,O=C([O-])[O-].[Na+].[Na+],test
US20100056511A1,CC(C)(N)CO.O=[N+]([O-])c1ccc(N=C=S)cc1>>CC(C)(CO)NC(=S)Nc1ccc([N+](=O)[O-])cc1,,C1CCOC1,,,,test
US20050119308A1,CC[N+]1(C)CCC(=O)CC1.NC1Cc2cccc3cccc1c23>>O=C1CCN(C2Cc3cccc4cccc2c34)CC1,,CCO,O,[I-].[K+],,test
US20160244431A1,CC(C)(C)OC(=O)NCCc1ccc(NC(=O)CN(Cc2ccccc2)Cc2ccccc2)cc1>>NCCc1ccc(NC(=O)CN(Cc2ccccc2)Cc2ccccc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030236287A1,COCCOc1ccc([N+](=O)[O-])c(OC)c1.Cl>>COCCOc1ccc(N)c(OC)c1.Cl,[Pd],CO,,,,test
US04880808,CNC(=O)C1CN(CC(=O)Nc2c(Cl)cc(C(C)=O)cc2Cl)CCN1.Fc1ccc(N(CCCCCl)c2ccc(F)cc2)cc1>>CNC(=O)C1CN(CC(=O)Nc2c(Cl)cc(C(C)=O)cc2Cl)CCN1CCCCN(c1ccc(F)cc1)c1ccc(F)cc1,,COCCO,,CCN(CC)CC,,test
US20060154960A1,CCI.CCc1n[nH]c2cc(C(=O)N(C)OC)ccc12>>CCc1nn(CC)c2cc(C(=O)N(C)OC)ccc12,,C1CCOC1,,CCOC(C)=O,CC(C)(C)[O-].[K+],test
US20140336052A1,C=CC[SnH3].CC1(C)CCCC(OS(=O)(=O)C(F)(F)F)=C1CC(=O)OCc1ccccc1>>C=CCC1=C(CC(=O)OCc2ccccc2)C(C)(C)CCC1,,C1COCCO1,,[Cl-].[Li+],,test
US20140303161A1,CCN(C(=O)OC(C)(C)C)C(C)(C)CO>>CCC(C)(C=O)N(C)C(=O)OC(C)(C)C,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20080176857A1,CCc1cc2c(N3CCN(C(=O)Cc4ccccc4)CC3)nc(Cl)nc2s1.O=C(CS)Nc1ccccc1>>CCc1cc2c(N3CCN(C(=O)Cc4ccccc4)CC3)nc(SCC(=O)Nc3ccccc3)nc2s1,,CN(C)C=O,,,,test
US20130225524A1,COc1cc(Nc2c(C(N)=O)cnc3cc(Br)ccc23)cc(C(=O)O)c1.Cc1noc(C)c1B(O)O>>COc1cc(Nc2c(C(N)=O)cnc3cc(-c4c(C)noc4C)ccc23)cc(C(=O)O)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20080004309A1,CCOC(=O)c1[nH]c2ccccc2c1C.Ic1ccccc1>>CCOC(=O)c1c(C)c2ccccc2n1-c1ccccc1,[Cu]I,,,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20050176772A1,COC(=O)/C=C\c1ccc(F)cc1F>>O=C(O)/C=C\c1ccc(F)cc1F,,C1CCOC1,,[Li+].[OH-],,test
US20150087585A1,BrCCBr.N#CCn1cc(Cl)cn1>>N#CC1(n2cc(Cl)cn2)CC1,,CS(C)=O,,[H-].[Na+],[Cl-].[NH4+],test
US20080070892A1,CC(C)N1CC2(CCN(C(=O)OC(C)(C)C)CC2)C1c1ccc(Cl)cc1>>CC(C)N1CC2(CCNCC2)C1c1ccc(Cl)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110217311A1,Cc1c(C(=O)O)sc2ncnc(Nc3ccc(F)cc3OC3CC4OCOC4C3)c12.NCCCN1CCCC1>>Cc1c(C(=O)NCCCN2CCCC2)sc2ncnc(Nc3ccc(F)cc3OC3CC4OCOC4C3)c12,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20080318954A1,N#Cc1ccnc(Cl)n1.Nc1ccc(Cl)nc1>>N#Cc1ccnc(Nc2ccc(Cl)nc2)n1,,CC#N,,,,test
US04386099,CN=C=S.Nc1ccc(-c2c[nH]cn2)cc1>>CNC(=S)Nc1ccc(-c2c[nH]cn2)cc1,,CCO,,,,test
US20060111336A1,C[C@@H](c1ccc(F)cc1)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CC[C@H](F)C1.O=C(O)C(F)(F)F>>C[C@@H](c1ccc(F)cc1)[C@H](N)C(=O)N1CC[C@H](F)C1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20050070542A1,COc1nc(C(C)C)ccc1B(O)O.Cc1nc2c(nc1Br)c(C)nn2C(C)C>>COc1nc(C(C)C)ccc1-c1nc2c(C)nn(C(C)C)c2nc1C,,Cc1ccccc1,,,,test
US20050130983A1,CCCBr.COC(=O)c1cc(S(=O)(=O)N2CCN(CCO)CC2)ccc1O>>CCCOc1ccc(S(=O)(=O)N2CCN(CCO)CC2)cc1C(=O)OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090318385A1,COc1ccc(C=Cc2ccncc2)c2cc(C(F)(F)F)nn12>>COc1ccc(CCc2ccncc2)c2cc(C(F)(F)F)nn12,[Pd],CCO,,,,test
US05166204,CI.CN(C)CCN1C(=O)c2ccc3[nH]c4ccc(Cl)cc4c3c2C1=O>>C[N+](C)(C)CCN1C(=O)c2ccc3[nH]c4ccc(Cl)cc4c3c2C1=O.[I-],,CN(C)C=O,,,,test
US20110053921A1,Nc1c(Cl)nc(Cl)nc1Cl.O=C(O)C1COCCN1>>O=C1Nc2c(Cl)nc(Cl)nc2N2CCOCC12,,CCO,O,CCN(CC)CC,,test
US04545942,C=CC#N.COC(=O)CN(C(=O)c1ccc(Cl)cc1)c1ccccc1>>COC(=O)CN(C(=O)c1ccc(Cl)cc1)c1ccccc1CCC#N,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20100216788A1,Cc1cc(N)ccc1Oc1cccc(C2(C(N)=O)CC2)c1.O=C(OCCn1ccc2ncnc(Cl)c21)c1ccccc1>>Cc1cc(Nc2ncnc3ccn(CCO)c23)ccc1Oc1cccc(C2(C(N)=O)CC2)c1,,CC(C)O,,[Na+].[OH-],[Cl-].[NH4+],test
US20160052884A1,COc1cn(CC(=O)OC(C)(C)C)c(=O)cc1-c1cc(Cl)ccc1C#N.O=CC1CC1(F)F>>COc1cn(C(=CC2CC2(F)F)C(=O)OC(C)(C)C)c(=O)cc1-c1cc(Cl)ccc1C#N,,C1CCOC1,,,,test
US04504304,C=CC(C)=O.CCOC(=O)C1CCCC1=O>>CCOC(=O)C1(CCC(C)=O)CCCC1=O,,CCN(CC)CC,,c1ccccc1,,test
US20090105253A1,CCNC(=O)c1ccc(-n2nnc(C(=O)NC3CC3)c2C)c(O)c1.ClCCBr>>CCNC(=O)c1ccc(-n2nnc(C(=O)NC3CC3)c2C)c(OCCCl)c1,,CCCCCC,CCOC(C)=O,,,test
US20150094306A1,CC(=O)Nc1nccc2c1CN(Cc1cnc(OCC(F)F)c(C)c1)C2=O.Cl>>Cc1cc(CN2Cc3c(ccnc3N)C2=O)cnc1OCC(F)F.Cl,,C1CCOC1,,,,test
US20050075378A1,Cc1oc(-c2ccccc2)nc1CCOc1ccc(CCC(=O)OC(C)(C)C)c(CN(C)C(=O)c2cc(Cl)sc2Cl)c1>>Cc1oc(-c2ccccc2)nc1CCOc1ccc(CCC(=O)O)c(CN(C)C(=O)c2cc(Cl)sc2Cl)c1,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US20090137609A1,CCC(O)(/C=C/c1ccc(C(CC)(CC)c2ccc(O)cc2)cc1C)CC.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCC(O)(/C=C/c1ccc(C(CC)(CC)c2ccc(OS(=O)(=O)C(F)(F)F)cc2)cc1C)CC,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20150158851A1,CCOC(=O)c1n[nH]c2c1CCC(c1cnn(COCC[Si](C)(C)C)c1)C2.C[Si](C)(C)CCOCCl>>CCOC(=O)c1nn(COCC[Si](C)(C)C)c2c1CCC(c1cnn(COCC[Si](C)(C)C)c1)C2,,C1CCOC1,,[H-].[Na+],,test
US20110060054A1,C=[N+](C)C.Cc1ccc(C=C2CCCC2=O)cc1.[Cl-]>>Cc1ccc(C=C2CCC(CN(C)C)C2=O)cc1.Cl,,CC#N,,,,test
US07135500B2,Cc1ccc(O)c(C)c1CC(C)(C)NCC(=O)c1ccc(OCc2ccccc2)c(OCc2ccccc2)c1C>>Cc1cc(O)cc(C)c1CC(C)(C)NCC(O)c1ccc(O)c(O)c1C,[Pd],,,CO,Cl,test
US20070155729A1,ClCBr.O=C(O)CCCCC(=O)OCNS(=O)(=O)c1cc(C(=O)OCC(Cl)(Cl)Cl)c(NCc2ccco2)cc1Cl>>O=C(CCCCC(=O)OCNS(=O)(=O)c1cc(C(=O)OCC(Cl)(Cl)Cl)c(NCc2ccco2)cc1Cl)OCCl,,CO,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080058383A1,Cc1cc(F)ccc1S(C)(=O)=O.NC1(CO)CCCC1>>Cc1cc(NC2(CO)CCCC2)ccc1S(C)(=O)=O,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US05554582,CCCC(=O)C1=C(O)CC(c2ccc(C(OC)OC)cc2)CC1=O.CCON>>CCCC(=NOCC)C1=CC(O)C(c2ccc(C(OC)OC)cc2)CC1=O,,CO,,O=C([O-])O.[Na+],,test
US20130231329A1,O=Cc1ccccc1.c1ccc2c(c1)ncn2CN1CCCC1>>OC(c1ccccc1)c1nc2ccccc2[nH]1,,C1CCOC1,,[Li]CCCC,,test
US20110136763A1,C1=COCCC1.CCc1cc(O)cc(O)c1C=O>>CCc1cc(OC2CCCCO2)cc(O)c1C=O,,ClCCl,,,,test
US06156914,CCN(CC)c1ccc2c(c1)OC(=C1Oc3cc(N(CC)CC)ccc3C1=O)C2=O>>CCN(CC)c1ccc2c(c1)OC(=C1Oc3ccccc3C1=O)C2=O,[Zn],CC(=O)O,,,,test
US20060217387A1,NCCN1CCOCC1.O=S(=O)(Cl)c1ccc(Cl)s1>>O=S(=O)(NCCN1CCOCC1)c1ccc(Cl)s1,,C1CCOC1,,CCN(CC)CC,,test
US20100197693A1,CCOC(=O)c1cccc(S(=O)(=O)Cl)c1.Nc1cccc(F)c1>>CCOC(=O)c1cccc(S(=O)(=O)Nc2cccc(F)c2)c1,,CC(=O)N(C)C,CCOC(C)=O,,,test
US20070185153A1,CN(C)C(OC(C)(C)C)N(C)C.COc1nc(C(=O)CF)c(NC(=O)OC(C)(C)C)cc1F>>COc1nc(C(=O)C(F)=CN(C)C)c(NC(=O)OC(C)(C)C)cc1F,,Cc1ccccc1,,,,test
US20140171404A1,CC(C)(C)OC(=O)NCCC=O.O=C(OCc1cc(Cl)cc(Cl)c1)N1CCNCC1>>CC(C)(C)OC(=O)NCCCN1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150376130A1,CCOC(=O)c1cccnc1NCCc1ccccc1>>O=C(O)c1cccnc1NCCc1ccccc1,,C1CCOC1,O,[Li+].[OH-],,test
US20060040970A1,COc1ccc2c3c1O[C@H]1[C@H](OS(=O)(=O)c4ccc(C)cc4)CC[C@H]4[C@@H](C2)N(C)CC[C@@]341.O=C1NC(=O)c2ccccc21>>COc1ccc2c3c1O[C@H]1[C@H](N4C(=O)c5ccccc5C4=O)CC[C@H]4[C@@H](C2)N(C)CC[C@@]341,,CN(C)C=O,,O,[K],test
US04065584,CC(CCl)CBr.Sc1ccccc1>>CC(CCl)CSc1ccccc1,,CCO,,[Na+].[OH-],,test
US06140274,CCc1cc(O)cc(CC)c1OCCCCOCC=C(Cl)Cl.ClCC=C(Cl)Cl>>CCc1cc(OCC=C(Cl)Cl)cc(CC)c1OCCCCOCC=C(Cl)Cl,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20110150834A1,CC(=O)CCC(=O)c1ccccc1.CCOC(=O)CN>>CCOC(=O)Cn1c(C)ccc1-c1ccccc1,,CCO,ClCCl,Cl,,test
US20060014777A1,CC(C)(C)OC(=O)N1C[C@@H]2c3cccc(C(F)(F)F)c3C(=O)N(CCO)[C@H]2C1.CI>>COCCN1C(=O)c2c(cccc2C(F)(F)F)[C@H]2CN(C(=O)OC(C)(C)C)C[C@@H]21,,C1CCOC1,COC(C)(C)C,[H-].[Na+],,test
US04484007,COC(C)(C)CCCC(C)CCC(O)c1ccc(C(C)C)cc1>>COC(C)(C)CCCC(C)CCCc1ccc(C(C)C)cc1,[Pd],CO,Cl,[H][H],,test
US04673508,C=CN1CCCC1=O.O=C1C=CC(=O)O1>>C=CN1CCCC1=O.O=C1C=CC(=O)O1,,C1COCCO1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20030092677A1,CC(C)(C)OC(=O)Nc1ccc(-c2ccc(F)cc2)cc1NC(=O)CC(=O)c1cccc(-n2ccnc2)c1>>O=C1CC(c2cccc(-n3ccnc3)c2)=Nc2ccc(-c3ccc(F)cc3)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100099715A1,Cc1nccc(Oc2ccc(B(O)O)c(F)c2)c1C.N#Cc1c(Br)ccn(CC2CC2)c1=O>>Cc1nccc(Oc2ccc(-c3ccn(CC4CC4)c(=O)c3C#N)c(F)c2)c1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])O.[Na+],,test
US05268377,C1CCOC1.CCCc1nc(CCN)cn1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1.CCO.CCOC(=O)C=O.O>>CCCc1nc2c(n1Cc1ccc(-c3ccccc3-c3nnn[nH]3)cc1)C(C(=O)OCC)NCC2.O=C(O)C(=O)O,,C1CCOC1,,Cl,,test
US20060199838A1,COc1cc(C(=O)O)ccc1OCc1ccccc1.COc1ccc(N)cc1OCc1ccccc1>>COc1cc(C(=O)Nc2ccc(OC)c(OCc3ccccc3)c2)ccc1OCc1ccccc1,,CN(C)C=O,,On1nnc2ccccc21,,test
US20040082611A1,Clc1ccc2cc[nH]c2c1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(c1ccccc1)n1ccc2ccc(Cl)cc21,,C1CCOC1,O,CCCCCC,[Li]CCCC,test
US20110288065A1,O=Cc1cc(Cl)nc(Cl)c1.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>Clc1cc(-c2cnco2)cc(Cl)n1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20150105373A1,CI.COCC(NC(=O)N1CC(=O)N(COCC[Si](C)(C)C)c2cc(O)cnc21)c1ccc(OC(F)(F)F)c(F)c1>>COCC(NC(=O)N1CC(=O)N(COCC[Si](C)(C)C)c2cc(OC)cnc21)c1ccc(OC(F)(F)F)c(F)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060247210A1,Cc1n[nH]c(N)c1-c1nc2ccc(S(=O)(=O)Cl)cc2s1.NCC(F)(F)F>>Cc1n[nH]c(N)c1-c1nc2ccc(S(=O)(=O)NCC(F)(F)F)cc2s1,,CO,,CN1CCOCC1,,test
US05780642,CC(C)(NCCCn1ccnc1)c1ccc(-c2ccc(OCc3ccccc3)cc2)cc1>>CC(C)(NCCCn1ccnc1)c1ccc(-c2ccc(O)cc2)cc1,[Pd],,,,,test
US05869492,Clc1ccc(SCC#CCOc2ccccc2)cc1.O=C(OO)c1cccc(Cl)c1>>O=S(CC#CCOc1ccccc1)c1ccc(Cl)cc1,,ClCCl,,,,test
US05948817,CO.O=C(O)c1c(Br)ccc2c1OCO2>>COC(=O)c1c(Br)ccc2c1OCO2,O=S(=O)(O)O,CO,,O=C([O-])O.[Na+],,test
US20070208064A1,Cc1ccc(-n2c(C(=O)O)cnc2S)cc1.Nc1ccc(F)cc1>>Cc1ccc(-n2c(C(=O)Nc3ccc(F)cc3)cnc2S)cc1,,c1ccncc1,,CCN=C=NCCCN(C)C,Cl,test
US20120214803A1,COc1ccnc2c([N+](=O)[O-])c(Cl)ccc12>>COc1ccnc2c(N)c(Cl)ccc12,[Pd],CCO,,,,test
US20060142357A1,CC(C)C1SC(NC23CC4CC(CC(C4)C2)C3)=NC1=O.ClC(Cl)(Cl)Cl.O=C1CCC(=O)N1Br>>COC1(C(C)C)SC(NC23CC4CC(CC(C4)C2)C3)=NC1=O,,ClC(Cl)(Cl)Cl,,,,test
US20080070965A1,CC(O)c1ccccc1Cl.COC(=O)c1sc(-n2cnc(Nc3ccccc3)n2)cc1O>>COC(=O)c1sc(-n2cnc(Nc3ccccc3)n2)cc1OC(C)c1ccccc1Cl,,C1CCOC1,CN(C)C=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060241127A1,Nc1ccc(Oc2cccc3onc(N)c23)c(F)c1.Nc1nc(Cl)cc(Cl)n1>>Nc1nc(Cl)cc(Nc2ccc(Oc3cccc4onc(N)c34)c(F)c2)n1,,O,,Cl,,test
US06740650B2,COc1ccc(Br)cc1OCc1ccccc1.O=[N+]([O-])O>>COc1cc([N+](=O)[O-])c(Br)cc1OCc1ccccc1,,CC(=O)O,,,,test
US20150284391A1,CCI.COc1ccc2c(Cl)nccc2c1O>>CCOc1c(OC)ccc2c(Cl)nccc12,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05700809,Brc1ccc2ccccc2c1.CC(=O)N1CCC(=O)CC1>>CC(=O)N1CCC(O)(c2ccc3ccccc3c2)CC1,,C1CCOC1,CCOCC,Cl,[Mg],test
US20110137070A1,CCOC(=O)C12CCC(NCc3ccccc3)(CC1)CC2O.CS(=O)(=O)Cl>>CCOC(=O)C12CCC(NCc3ccccc3)(CC1)CC2OS(C)(=O)=O,,C1CCOC1,,CCN(CC)CC,Cc1ccccc1,test
US20110136763A1,CCOC(=O)CC1OB(O)c2cc(O)cc(COC)c21>>COCc1cc(O)cc2c1C(CC(=O)O)OB2O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20100317624A1,CCn1cc(C(=O)O)c(=O)c2cc(I)c(F)cc21.CN1CCNCC1>>CCn1cc(C(=O)O)c(=O)c2cc(I)c(N3CCN(C)CC3)cc21,,CN(C)C=O,,CCN(CC)CC,,test
US20130330876A1,CCCCCCCCCCc1ccc2cc(OS(=O)(=O)C(F)(F)F)c(SC)cc2c1.CN(C)C=O.c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCCCCCCCCc1ccc2cc(/C=C/c3cc4ccc(CCCCCCCCCC)cc4cc3SC)c(SC)cc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,,,test
US20130029961A1,CCOC(=O)C(C)c1cnc(N)c(OC)c1.CS(=O)(=O)Cl>>CCOC(=O)C(C)c1cnc(NS(C)(=O)=O)c(OC)c1,,C1CCOC1,,CCN(CC)CC,,test
US20100016164A1,CC(CO)CCNCc1ccccc1[N+](=O)[O-].O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC1CCN(Cc2ccccc2[N+](=O)[O-])C(=O)OC1,,Cc1ccccc1,,CCN(CC)CC,O,test
US20100120741A1,Cn1cnc2cnc3ccc(Cl)cc3c21.OO>>Cn1cnc2c(=O)[nH]c3ccc(Cl)cc3c21,,CC(=O)O,,,,test
US20070060754A1,CC(=O)OC(C)=O.CCCn1c(COCC)nc2c(N)nc3cc(OC4CCNCC4)ccc3c21>>CCCn1c(COCC)nc2c(N)nc3cc(OC4CCN(C(C)=O)CC4)ccc3c21,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20030100576A1,COC(=O)C(Br)c1ccccc1.c1ccc(N2CCNCC2)nc1>>COC(=O)C(c1ccccc1)N1CCN(c2ccccn2)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20110136833A1,C#CCO.O/N=C(\Br)C(F)(F)F>>OCc1cc(C(F)(F)F)no1,,Cc1ccccc1,,CCN(CC)CC,,test
US20090275578A1,CC(N)CCc1ccccc1.COC(=O)c1ccccc1CBr>>CC(CCc1ccccc1)N1Cc2ccccc2C1=O,,CCCCCC,Cc1ccccc1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US04174448,COCCl.Clc1ccccc1CNCCc1cccs1>>Cl.Clc1ccccc1CN1CCc2sccc2C1,,CN(C)C=O,,O,,test
US20030095958A1,CC(C)(C)OC(=O)N1CCN(c2cc(OCc3ccccc3)ccc2[N+](=O)[O-])CC1>>CC(C)(C)OC(=O)N1CCN(c2cc(OCc3ccccc3)ccc2N)CC1,,CO,ClCCl,[BH4-].[Na+],,test
US05204333,BrC1CCC1.CCOC(=O)CC(=O)OCC>>CCOC(=O)C(C(=O)OCC)C1CCC1,,CCO,,[Na],,test
US03931235,C=CCSc1c(O)cc(C)oc1=O.OO>>C=CCS(=O)c1c(O)cc(C)oc1=O,,CC(=O)O,,,,test
US20130102585A1,COC(=O)c1ccc2c(-c3ccc(F)cc3)cn(C(=O)OC(C)(C)C)c2c1>>COC(=O)c1ccc2c(-c3ccc(F)cc3)c[nH]c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090298896A1,CCOC(=O)CBr.CNc1ccc(C(=O)CCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C(C)C)cc1>>CC(C)c1nc(-c2ccc(C(F)(F)F)cc2)sc1CCC(=O)c1ccc(N(C)CC(=O)O)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,,test
US05369159,CC(C)(C)c1ccc(O)c(C(C)(C)C)c1.O=C(O)C(O)c1ccc(O)cc1>>CC(C)(C)c1cc2c(c(C(C)(C)C)c1)OC(=O)C2c1ccc(O)cc1,,CC(=O)O,,O,,test
US20080146566A1,COC(=O)c1ccc(C)c(-n2ccc3ccc(N4CCN(C)CC4)cc3c2=O)c1>>Cc1ccc(C(=O)O)cc1-n1ccc2ccc(N3CCN(C)CC3)cc2c1=O,,CO,,Cl,[Na+].[OH-],test
US20160068487A1,CCOC(=O)CC1(C)CCc2cc(B3OC(C)(C)C(C)(C)O3)ccc2C1=O.O=[N+]([O-])c1ccc(Br)nc1>>CCOC(=O)CC1(C)CCc2cc(-c3ccc([N+](=O)[O-])cn3)ccc2C1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04803216,COc1ccccc1N.Cc1ccc(S(=O)(=O)N2CCC(N)=N2)cc1>>COc1ccccc1NC1=NN(S(=O)(=O)c2ccc(C)cc2)CC1,,CC(=O)O,,,,test
US20050038256A1,COc1ccc(CCO[C@@H]2CCCC[C@@H]2O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1OC>>COc1ccc(CCO[C@@H]2CCCC[C@@H]2O)cc1OC,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20050118202A1,COc1cc2c(cc1OC)C(=O)OC2=O.Cc1ccc(C2c3c(C)c(N)c(C)c(C)c3OC2(C)C)cc1>>COc1cc2c(cc1OC)C(=O)N(c1c(C)c(C)c3c(c1C)C(c1ccc(C)cc1)C(C)(C)O3)C2=O,,C1CCOC1,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20140170207A1,CCCCCCCCCCCC(C)(C)OC(=O)C(C)Br.CNC>>CCCCCCCCCCCC(C)(C)OC(=O)C(C)N(C)C,,CC#N,,O=C([O-])O.[Na+],,test
US20060106020A1,COC(OC)N(C)C.O=C(Cc1ccnc(F)c1)c1ccc(F)cc1>>CN(C)C=C(C(=O)c1ccc(F)cc1)c1ccnc(F)c1,,C1CCOC1,,,,test
US20150087626A1,COC(=O)c1ccc([C@H](C)NC(=O)[C@H]2CC(F)(F)CN2Cc2cccc(C(F)(F)F)c2)cc1>>COC(=O)c1ccc([C@H](C)NC(=O)[C@H]2CC(F)(F)CN2)cc1,[Pd],CO,Cl,,,test
US20110263612A1,Nc1ccc(-c2cc3c(cc2Br)CCO3)cn1.O=C(Cl)c1c(F)cccc1F>>O=C(Nc1ccc(-c2cc3c(cc2Br)CCO3)cn1)c1c(F)cccc1F,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US03932644,CCOc1cccc(NCCSCc2[nH]cnc2C)n1>>Cc1nc[nH]c1CSCCNc1cccc(=O)[nH]1,,Cl,,,,test
US20040162314A1,CCOC(=O)C(Cc1cccc(-c2cc(C(C)C)cc3cccnc23)c1)c1ccncc1>>CC(C)c1cc(-c2cccc(CC(CO)c3ccncc3)c2)c2ncccc2c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040186118A1,CCOC(=O)Cl.NCCCNc1nc(Nc2cccc(NC(=O)N3CCCC3)c2)ncc1Br>>CCOC(=O)NCCCNc1nc(Nc2cccc(NC(=O)N3CCCC3)c2)ncc1Br,,c1ccncc1,,,,test
US20030099598A1,Cc1ccc2c(c1)C=CC(C)(C)N2.O=C(OO)c1cccc(Cl)c1>>Cc1ccc2c(c1)C=CC(C)(C)[NH+]2[O-],,ClCCCl,,,,test
US20110105567A1,CCC=Cc1c(C(=O)OC)c(C(C)C)n(Cc2ccccc2)c1CC>>CCCCc1c(C(=O)OC)c(C(C)C)n(Cc2ccccc2)c1CC,[Pd],C1CCOC1,,,,test
US20040259904A1,C=CCOc1ccc2c(c1)Cc1c(-c3ccc(C#N)cc3)n[nH]c1-2.[N-]=[N+]=[N-]>>C=CCOc1ccc2c(c1)Cc1c(-c3ccc(-c4nnn[nH]4)cc3)n[nH]c1-2,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20120094972A1,COC(=O)C1(c2ccc(Br)cc2[N+](=O)[O-])CCOCC1>>O=C1Nc2cc(Br)ccc2C12CCOCC2,[Fe],CC(=O)O,,,,test
US20150119373A1,C=C(C)[C@@H]1CC[C@]2(C(=O)N[C@@H]3C[C@H](c4nnc(C)o4)C3(C)C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(C)=O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(C(=O)N[C@@H]3C[C@H](c4nnc(C)o4)C3(C)C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1CCOC1,ClCCl,CO,,test
US20060106016A1,COc1ccc(CCl)cc1.OC/C=C/CO>>COc1ccc(COC/C=C/CO)cc1,,CN(C)C=O,,[H-].[Na+],,test
US05580751,COc1ccc(C[NH-])c(OC)c1.O=C(N[C@@H](Cc1ccccc1)C(=O)O)c1ccccc1>>NC(=O)[C@@H](N)Cc1ccccc1,,O=C(O)C(F)(F)F,,O=S(=O)(O)C(F)(F)F,,test
US20040018192A1,CCCCC([Sn])=C(CCCC)CCCC.CCOC(=O)c1cnc2c(Cl)cccc2c1Cl>>C=Cc1c(C(=O)OCC)cnc2c(Cl)cccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US06140332,Cc1c(-c2ccc(O)cc2)[nH]c2ncnc(Nc3cccc(Cl)c3)c12.Cl>>Cc1c(-c2ccc(O)cc2)[nH]c2ncnc(Nc3cccc(Cl)c3)c12.Cl,,CCOC(C)=O,,Br,[Na+].[OH-],test
US20050176750A1,N#CC1=C(N)Oc2cc(N)ccc2C1c1ccccc1>>N#CC1=COc2ccccc2C1c1ccccc1,,CN(C)C=O,,CC(C)(C)ON=O,,test
US04051130,COC(=O)c1cccc(C)c1NS(=O)(=O)NC(C)C>>Cc1cccc2c1NS(=O)(=O)N(C(C)C)C2=O,,CO,,C[O-].[Na+],,test
US05714479,CCOC(=O)c1cncnc1C(=O)OCC.COc1ccc([Mg]Br)cc1>>CCOC(=O)c1cncnc1C(=O)c1ccc(OC)cc1,,C1CCOC1,,Cl,,test
US20110212103A1,CC(F)COc1ncccc1[N+](=O)[O-]>>CC(F)COc1ncccc1N,[Pd],C1CCOC1,CO,,,test
US20140323303A1,CI.Cc1cc(Br)cc(C)c1C1C(=O)CCC1=O>>COC1=C(c2c(C)cc(Br)cc2C)C(=O)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04012514,C#CC(O)c1ccc(F)cc1.C=O.O=c1[nH]c2ccccc2n1C1CCNCC1>>O=c1[nH]c2ccccc2n1C1CCN(CC#CC(O)c2ccc(F)cc2)CC1,,C1COCCO1,O,,,test
US20110224155A1,CC(=O)Cl.CC(C)(O)CCOc1cccc([N+](=O)[O-])c1C#N>>CC(=O)OC(C)(C)CCOc1cccc([N+](=O)[O-])c1C#N,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20060063809A1,Cc1cccc(-c2[nH]c(C3CCNCC3)nc2-c2ccc3c(c2)OCO3)n1.O=S(=O)(Cl)Cc1ccccc1>>Cc1cccc(-c2[nH]c(C3CCN(S(=O)(=O)Cc4ccccc4)CC3)nc2-c2ccc3c(c2)OCO3)n1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090298883A1,CC(C)(C)OC(=O)N1CCC(CN)CC1.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>O=C(NCC1CCNCC1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,ClCCl,O,CCN(C(C)C)C(C)C,Cl,test
US05935908,CC(=NO)c1nn(C)c2cc(OCC3CC3(Cl)Cl)c(F)cc12.COC=C(C(=O)OC)c1ccccc1CBr>>COC=C(C(=O)OC)c1ccccc1CON=C(C)c1nn(C)c2cc(OCC3CC3(Cl)Cl)c(F)cc12,,CN(C)C=O,,CC(=O)O,[H-].[Na+],test
US20100292188A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C(Nc1cnccc1Cl)c1ccc(O[C@@H]2C[C@@H](N3CCCCC3)C2)cc1>>c1cc2sc(-c3ccc(O[C@@H]4C[C@@H](N5CCCCC5)C4)cc3)nc2cn1,,Cc1ccccc1,,,,test
US20150094330A1,COC(=O)c1ccc(CCc2cccc3c2N(Cc2cc(OC)cc(OC)c2)CCC3)cc1.O=C(O)c1ccc(CCc2cccc3c2N(Cc2cccc(F)c2)CC3)cc1>>COc1cc(CN2CCCc3cccc(CCc4ccc(C(=O)O)cc4)c32)cc(OC)c1,,C1COCCO1,,[Li+].[OH-],,test
US20140256936A1,CCOCCOCCOCCO.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1,,ClCCl,O,[Na+].[OH-],,test
US20140128372A1,CCOC(=O)c1c(C)nc2c(O)cc(F)cn12.Fc1cccc(F)c1CBr>>CCOC(=O)c1c(C)nc2c(OCc3c(F)cccc3F)cc(F)cn12,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US08518934B2,C1CCNCC1.O=C(NOC1CCNCC1)Nc1ccc(F)cc1.O=S(=O)(Cl)Cl>>O=C(NOC1CCN(S(=O)(=O)N2CCCCC2)CC1)Nc1ccc(F)cc1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20070027160A1,O=C1CCN(c2ccc(F)c3cccnc23)CC1.c1cnc2c(N3CCNCC3)cccc2c1>>Fc1ccc(N2CCC(N3CCN(c4cccc5cccnc45)CC3)CC2)c2ncccc12,,CC(=O)O,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20050203079A1,CC(C)(C)O[K].COc1ccc(N2CCC(c3ccc(Cl)c(Cl)c3)C2=O)cc1OCCN1CCC(C)CC1>>COc1ccc(N2CCC(O)(c3ccc(Cl)c(Cl)c3)C2=O)cc1OCCN1CCC(C)CC1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20110112089A1,CC(c1ccc(Br)o1)N1CCOCC1.CCO.O=C(O)Cc1ccc(B(O)O)cc1>>COC(=O)c1ccc(-c2ccc(C(C)N3CCOCC3)o2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20120010190A1,CCCCCCC.O/N=C(\CC(c1ccccc1)c1cccc(Br)c1)c1ccncc1>>CCC(CC(=NO)c1ccncc1)c1cccc(Br)c1,,CCCCCCC,,CC(C)O,,test
US20080214598A1,CC(C)(C)[SiH2]OC(C)(C)c1cc(CCN)ccc1Cl.O=C(O)CC(F)(F)F>>CC(C)(C)[SiH2]OC(C)(C)c1cc(CCNC(=O)CC(F)(F)F)ccc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20040147519A1,Cc1cc(CCN2C(=O)c3ccccc3C2=O)ccn1>>Cc1cc(CCN)ccn1,,CCO,,,,test
US04060613,CC(=O)OCC(COc1cccc2ccccc12)N1CCCCC1>>OCC(COc1cccc2ccccc12)N1CCCCC1,,CO,O,[K+].[OH-],,test
US20140005245A1,COC(=O)c1cc(-c2cn(-c3c(C(F)(F)F)c(C(F)(F)C(F)(F)F)nn3C)nn2)ccc1Cl>>Cn1nc(C(F)(F)C(F)(F)F)c(C(F)(F)F)c1-n1cc(-c2ccc(Cl)c(C(=O)O)c2)nn1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20060281784A1,CC(C)CN(CC(C)C)C(=O)C(C)(C)c1ccc([N+](=O)[O-])c(NCCCN2CCCCC2)c1>>CC(C)CN(CC(C)C)C(=O)C(C)(C)c1ccc(N)c(NCCCN2CCCCC2)c1,[Pd],CCO,CCOC(C)=O,,,test
US06127368,COCc1c(C(=O)OC(C)C)ncc2[nH]c3ccc4oc(C5COC(C)(C)O5)nc4c3c12>>COCc1c(C(=O)OC(C)C)ncc2[nH]c3ccc4oc(C(O)CO)nc4c3c12,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20140005164A1,COc1ccc2c(c1)n(C[C@@H]1CC[C@@H](C(=O)NNC(=O)c3cn(C)nc3C(F)(F)F)CC1)c(=O)n2C>>COc1ccc2c(c1)n(C[C@@H]1CC[C@@H](c3nnc(-c4cn(C)nc4C(F)(F)F)o3)CC1)c(=O)n2C,CN(C)c1ccncc1,ClCCl,,Cc1ccc(S(=O)(=O)Cl)cc1,,test
US05559106,CCOP(=O)(CC(=O)NNc1nc2ccc3ccccc3c2n(Cc2ccc(OC)cc2OC)c1=O)OCC>>CCOP(=O)(Cc1nnc2c(=O)[nH]c3c4ccccc4ccc3n12)OCC,,CC(=O)O,,,,test
US20040138286A1,CC(=O)Cl.c1cc2[nH]ncc2cc1NC1CCNCC1>>CC(=O)N1CCC(Nc2ccc3[nH]ncc3c2)CC1,,C1CCOC1,,CCN(CC)CC,[Na+].[OH-],test
US20020156081A1,CC(C)(C)OC(=O)N(CCO)CCC(=O)N1CC(n2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CN(C(=O)CCNCCO)C1,,CC(C)=O,,Cl,,test
US04837225,CCOC(=O)c1ccc(NC(=S)NCCn2c(C)ccc2C)cc1>>Cc1ccc(C)n1CCNC(=S)Nc1ccc(C(=O)O)cc1,,[Na+],[OH-],,,test
US20140094453A1,NC1=NS(=O)(=O)Nc2cccc(OC[C@H]3CCC[NH2+]C3)c21.O=C(NCc1ccncc1)Oc1ccc([N+](=O)[O-])cc1>>NC1=NS(=O)(=O)Nc2cccc(OC[C@H]3CCCN(C(=O)NCc4ccncc4)C3)c21,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US04602092,CCOP([O-])CCCCc1ccccc1.O=C(CBr)N1CCC[C@@]1(Cc1ccccc1)C(=O)O>>CCOP(=O)(CCCCc1ccccc1)CC(=O)N1CCC[C@H]1C(=O)O,,ClC(Cl)Cl,,CCN(CC)CC,C[Si](C)(C)Cl,test
US20020173653A1,CCCCc1nc2c(N)nc3cccnc3c2n1CCCCN.O=C=NCc1ccccc1>>CCCCc1nc2c(N)nc3cccnc3c2n1CCCCNC(=O)NCc1ccccc1,,C1CCOC1,,CO,ClCCl,test
US20150038438A1,COc1ccc(CN)c(OC)c1.Cn1c(CO[Si](C)(C)C(C)(C)C)cc2cc3c(cc21)N(C(=O)OC(C)(C)C)CCCC3=O>>COc1ccc(CN=C2CCCN(C(=O)OC(C)(C)C)c3cc4c(cc32)cc(CO[Si](C)(C)C(C)(C)C)n4C)c(OC)c1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,CCN(CC)CC,,test
US07855292B2,CC(C)(C)OO.OCC=Cc1ccc(Cl)c(Cl)c1>>OC[C@@H]1O[C@H]1c1ccc(Cl)c(Cl)c1,,ClCCl,,,,test
US20130203776A1,O=C(NCCCCl)c1cnn2ccc(N3CCC[C@@H]3c3cc(F)cnc3O)nc12>>O=C1NCCCOc2ncc(F)cc2[C@H]2CCCN2c2ccn3ncc1c3n2,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040063698A1,CCOC(=O)C(C)(C)C(O)c1ccc(OCc2cc(C)nc3ccccc23)cc1.NO.O=C(O)C(F)(F)F>>Cc1cc(COc2ccc(C(O)C(C)(C)C(=O)NO)cc2)c2ccccc2n1.O=C(O)C(F)(F)F,,C1CCOC1,,CO,[K+].[OH-],test
US20080255083A1,C=O.CC(C)(C)OC(=O)N1CCc2ccc(CCn3ncc(OCc4ccccc4)cc3=O)cc2C1>>CN1CCc2ccc(CCn3ncc(OCc4ccccc4)cc3=O)cc2C1,CC(=O)O,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US04550105,C=CCO/N=C(\C(=O)OC)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>C=CCO/N=C(\C(=O)OC)c1csc(N)n1,,C1CCOC1,,O=CO,,test
US20040082638A1,CC(C)[C@@H](N)c1oc2cc(Cl)ccc2c(=O)c1Cc1ccccc1.O=C(CBr)CN1C(=O)c2ccccc2C1=O>>CC(C)[C@@H](NCC(=O)CN1C(=O)c2ccccc2C1=O)c1oc2cc(Cl)ccc2c(=O)c1Cc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140005213A1,C=C(C)C(=O)N1C(=O)OC[C@H]1c1ccccc1.COCN(Cc1ccccc1)C[Si](C)(C)C>>C[C@]1(C(=O)N2C(=O)OC[C@H]2c2ccccc2)CCN(Cc2ccccc2)C1,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US20060030613A1,CC(C)(C)c1ccc(C=O)cc1.NCCc1cccc(Cl)c1>>CC(C)(C)c1ccc(CNCCc2cccc(Cl)c2)cc1,Cl,CO,,[BH4-].[Na+],,test
US20090036492A1,Cc1cc(O)c2ccccc2c1C=O.Fc1ccc(CBr)cc1>>Cc1cc(OCc2ccc(F)cc2)c2ccccc2c1C=O,,CN(C)C=O,,[H-].[Na+],,test
US04799934,NCC(O)CO.O=[N+]([O-])c1ccc(F)cc1F>>O=[N+]([O-])c1ccc(F)cc1NCC(O)CO,,CS(C)=O,,CCOC(C)=O,,test
US20060229307A1,CC(C)(C)c1ccc(N)cc1.Cc1cccnc1-c1ccc2c(Cl)nncc2c1>>Cc1cccnc1-c1ccc2c(Nc3ccc(C(C)(C)C)cc3)nncc2c1.Cl,,C1COCCO1,,,,test
US20130079329A1,NC1CCCCC1.O=C(O)c1cncc(Br)c1>>O=C(NC1CCCCC1)c1cncc(Br)c1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05266570,C=COC(C)=O.O=Cc1c2ccccc2cc2ccc(Cl)cc12>>CC(=O)OC1CC2c3ccccc3C1(C=O)c1cc(Cl)ccc12,,CCOCC,,,,test
US20070032469A1,CC(C)(C)OC(=O)Nc1ccc(F)cc1.ClCCCI>>CC(C)(C)OC(=O)N1CCCc2cc(F)ccc21,,C1CCOC1,,CCCCC,[Li]C(C)(C)C,test
US20070249607A1,CC(C)(C)OC(=O)N1CCC(C(=O)O)(c2ccc(F)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(CO)(c2ccc(F)cc2)CC1,,C1CCOC1,CCOC(C)=O,B,CO,test
US20130064770A1,O=C(NCCN1CCNCC1)C1CCCCC1.O=[N+]([O-])c1cccc(Cl)n1>>O=C(NCCN1CCN(c2cccc([N+](=O)[O-])n2)CC1)C1CCCCC1,,CC#N,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20080214642A1,NNC(=O)c1ccc(Cl)cc1.O=C(CC(=O)C(F)(F)F)c1cc(F)ccc1F>>O=C(c1ccc(Cl)cc1)N1N=C(C(F)(F)F)CC1(O)c1cc(F)ccc1F,,CCO,,,,test
US20160108040A1,CS(=O)(=O)Cl.C[C@H]1CCC[C@@H](C)N1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4cncc(OCCO)c4)c4ccccc43)cn12>>C[C@H]1CCC[C@@H](C)N1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4cncc(OCCOS(C)(=O)=O)c4)c4ccccc43)cn12,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090186886A1,CN(C)CCN.[O-][n+]1nc(Cl)nc2cc3c(cc21)CCO3>>CN(C)CCNc1nc2cc3c(cc2[n+]([O-])n1)CCO3,,COCCOC,,,,test
US20160050924A1,C=Cc1cccnc1-n1ncc(C(=O)N(C)c2cccnc2)c1C>>CCc1cccnc1-n1ncc(C(=O)N(C)c2cccnc2)c1C,[Pd],CCO,,,,test
US20090281086A1,CC(Oc1ccsc1C(N)=O)c1ccc(F)c(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)c1>>CC(Oc1ccsc1C(N)=O)c1ccc(F)c(C(=O)N2CCNCC2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150336979A1,CCOC(=O)CC[C@H]1CO[C@@H]2[C@@H](NC(=O)NC3CCCCC3)CO[C@H]12>>O=C(O)CC[C@H]1CO[C@@H]2[C@@H](NC(=O)NC3CCCCC3)CO[C@H]12,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20110152315A1,CCOC(=O)COc1ccc(C#Cc2ccc(CO)cc2)cc1>>O=C(O)COc1ccc(C#Cc2ccc(CO)cc2)cc1,,C1CCOC1,O,Cl,[Li]O,test
US04994569,O=C=Nc1ccc(Cl)c(Cl)c1.OC1COC(c2ccccc2)=NC1c1ccccc1>>O=C(Nc1ccc(Cl)c(Cl)c1)OC1COC(c2ccccc2)=NC1c1ccccc1,,ClCCCl,,,,test
US20150111885A1,CI.O=c1[nH]cc(Br)c2ncncc12>>Cn1cc(Br)c2ncncc2c1=O,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20110105535A1,CCOC(=O)C(Cc1nnc(NC(N)=S)s1)C(=O)OC>>NC(=S)Nc1nnc(CCC(=O)O)s1,,[Na+],[OH-],Cl,,test
US20110152273A1,COC(=O)c1c(C#N)cc(N[C@@H]2CCCC[C@@H]2N)nc1Nc1cccc(S(C)(=O)=O)c1>>CS(=O)(=O)c1cccc(Nc2nc(N[C@@H]3CCCC[C@@H]3N)cc3c2C(=O)NC3)c1,[Pd],Cl,,CO,,test
US20060160864A1,CC(C)CN(C)c1ccc(Br)cc1C=O.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)/C=C/c1cc(Br)ccc1N(C)CC(C)C,,Cc1ccccc1,,O,[H-].[Na+],test
US08912186B2,CCOC(=O)CNc1ccccc1.O=C(Cl)Cc1ccc(Cl)cc1>>CCOC(=O)CN(C(=O)Cc1ccc(Cl)cc1)c1ccccc1,,ClCCl,,Cl,c1ccncc1,test
US20030109459A1,COC(=O)C1(Cc2ccc(-c3nnnn3C)cc2)CCC1>>Cn1nnnc1-c1ccc(CC2(C(=O)O)CCC2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20120252778A1,CCOC(CC)OCC.CCc1nn2c(C)cc(C)nc2c1Cc1ccc(N=[N+]=[N-])cc1>>CCOC(OCC)c1cn(-c2ccc(Cc3c(CC)nn4c(C)cc(C)nc34)cc2)nn1,[Cu]I,CC#N,CCOC(C)=O,,,test
US20080045536A1,NN.O=C1C=C(c2cccc(Cl)c2)C(=O)O1>>Oc1cc(-c2cccc(Cl)c2)c(O)nn1,,CC(=O)O,O,,,test
US05798311,CCCN.O=C(CBr)c1ccc(Cl)cc1.O=C(Cl)OCC(Cl)(Cl)Cl>>CCCN(CC(=O)c1ccc(Cl)cc1)C(=O)OCC(Cl)(Cl)Cl,,ClCCl,O,[Na+].[OH-],,test
US20090227622A1,O=C1CCC(=O)N1Br.c1csc(-c2ccn3ccnc3c2)n1>>Brc1cnc2cc(-c3nccs3)ccn12,,CCO,ClCCl,,,test
US20040077646A1,CCN=C=NCCCN(C)C.CN(C)C=O.CN1CCOCC1.Cn1c(C(=O)N[C@H]2CCCC[C@H]2C(=O)O)cc2ccccc21.On1nnc2ccccc21>>Cn1c(C(=O)N[C@H]2CCCC[C@H]2C(=O)NC(C#N)Cc2ccncc2)cc2ccccc21,,CN(C)C=O,O,,,test
US20090221551A1,CC(C)(C)OC(=O)N1CCCn2c1nc1c(N)nc3cc(Br)ccc3c12.O=C(O)C(F)(F)F>>Nc1nc2cc(Br)ccc2c2c1nc1n2CCCN1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20140080756A1,CCOC(=O)CC(=O)CCl.Cc1nnc(N)s1>>CCOC(=O)Cc1cn2nc(C)sc2n1,,CCO,,,,test
US20050038065A1,CCOC(=O)c1c[nH]c2ccc(OCC)nc2c1=O.NCc1ccccc1>>CCOc1ccc2[nH]cc(C(=O)NCc3ccccc3)c(=O)c2n1,,CC(=O)N(C)C,,O,,test
US20110166121A1,CCCc1cc2c(N3CCn4c(nnc4C(F)(F)F)C3)nc(OCc3nc(CC(=O)OCC)co3)nc2s1>>CCCc1cc2c(N3CCn4c(nnc4C(F)(F)F)C3)nc(OCc3nc(CC(=O)O)co3)nc2s1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20090181942A1,COc1cccc(C=O)c1OC.Fc1cc(Cl)cc(Br)c1-n1cccc1>>COc1cccc(C(O)c2cc(Cl)cc(F)c2-n2cccc2)c1OC,,C1CCOC1,CCOCC,[Li]CCCC,[Cl-].[NH4+],test
US20130267542A1,BrBr.CCC(=O)Nc1ccc(F)c(Cl)c1>>CCC(=O)Nc1cc(Cl)c(F)cc1Br,,CC(=O)O,,,,test
US20120329785A1,CC1(C)CNc2cc(N)ccc2S1.COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1>>COc1ccc2nc(Nc3ccc4c(c3)NCC(C)(C)S4)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US05463077,COc1ccccc1[C@]1(O)CCC(c2ccccc2)(c2ccccc2)[C@H]2CN(C(=O)OC(C)(C)C)C[C@H]21.Cl>>COc1ccccc1C1=CCC(c2ccccc2)(c2ccccc2)[C@H]2CNC[C@@H]12.Cl,,CC(=O)O,,,,test
US20080262050A1,CCOC(=O)CCCCc1ccc2cc(O)c(N3CC(=O)NS3(=O)=O)cc2c1>>O=C(O)CCCCc1ccc2cc(O)c(N3CC(=O)NS3(=O)=O)cc2c1,,CO,O,[K+].[OH-],,test
US20030045552A1,CCCCCCC(=O)Cl.NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O>>CCCCCCC(=O)NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O,,CC#N,,C1CCC2=NCCCN2CC1,Cl,test
US20040023989A1,CCCCc1[nH]nc(C(N)=O)c1[N+](=O)[O-]>>CCCCc1[nH]nc(C(N)=O)c1N,[Pd],CCO,,,,test
US06884821B1,CCOC(=O)C(CC)Cc1ccc(OC)c(CC(=O)Nc2ccc(Cl)cc2Cl)c1>>CCC(Cc1ccc(OC)c(CC(=O)Nc2ccc(Cl)cc2Cl)c1)C(=O)O,,CCO,,O,[Na+].[OH-],test
US20120046285A1,Cc1cc(Cl)c2cccc(O)c2n1.NCc1ccccn1>>Cc1cc(NCc2ccccn2)c2cccc(O)c2n1,,CS(C)=O,,CCOC(C)=O,,test
US20140171435A1,CC(C)N.Nc1c(Cl)cnnc1Cl>>CC(C)Nc1nncc(Cl)c1N,,CO,,CC(=O)O,,test
US20100261728A1,CCOC(=O)Cl.c1ccc2cnccc2c1>>CCOC(=O)c1nccc2ccccc12.[Cl-],,C1CCOC1,,,,test
US20040147535A1,CN(C)C(N)=O.O=C(Nc1cc2ccccc2cn1)c1ccccc1NCc1ccnc(Br)c1>>CN(C)C(=O)Nc1cc(CNc2ccccc2C(=O)Nc2cc3ccccc3cn2)ccn1,,C1COCCO1,ClCCl,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20040186108A1,CC(=O)Cl.CNc1ccccc1CCN1CCN(c2nsc3ccccc23)CC1>>CC(=O)N(C)c1ccccc1CCN1CCN(c2nsc3ccccc23)CC1,,CC(Cl)Cl,,CCN(CC)CC,,test
US20160194302A1,CCOC(=O)Cn1ccnc1CCC(=O)O.CN(C)[C@@H]1CCCNC1>>CCOC(=O)Cn1ccnc1CCC(=O)N1CCC[C@@H](N(C)C)C1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US03960845,C[Si](C)(C)Cl.Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(NC(=O)C(Cl)Cl)[C@H]2SC1>>Cn1nnnc1SCC1=C(C(=O)O[Si](C)(C)C)N2C(=O)C(NC(=O)CCl)[C@H]2SC1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20030017948A1,CCS(=O)(=O)N(c1cc([N+](=O)[O-])c(F)cc1Br)S(=O)(=O)CC>>CCS(=O)(=O)N(c1cc(N)c(F)cc1Br)S(=O)(=O)CC,[Fe],CC(=O)O,,,,test
US20150011548A1,CC(=O)Cl.O=S(=O)(Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cn[nH]c4)ccc32)c1)C1CC1>>CC(=O)n1cc(-c2ccc3c(c2)ncn3-c2cc(NS(=O)(=O)C3CC3)cc(-c3ccc(F)cc3F)c2)cn1,,ClCCl,,,,test
US20040044211A1,CN1Cc2c(Cl)cc(Cl)cc2C(c2cccc(N)c2)C1.O=CO>>CN1Cc2c(Cl)cc(Cl)cc2C(c2cccc(NC=O)c2)C1,,O=CO,,CCOC(C)=O,O=C([O-])O.[Na+],test
US20150087663A1,CC[C@H](N)c1nc2cccc(F)c2c(=O)n1C1CC1.Cc1noc(-c2c(N)ncnc2Cl)n1>>CC[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1nc2cccc(F)c2c(=O)n1C1CC1,,CCCCO,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20120184542A1,COc1ncc2cc(C(=O)Nc3cc(C(=O)O)ccc3Cl)c(=O)[nH]c2n1.NCc1cccc(C(F)(F)F)c1>>COc1ncc2cc(C(=O)Nc3cc(C(=O)NCc4cccc(C(F)(F)F)c4)ccc3Cl)c(=O)[nH]c2n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140005222A1,CCOC(=O)c1cc(C)c(NC(=O)c2nc(N3CCC(O[Si](C)(C)C(C)(C)C)CC3)ccc2C)c(C)c1>>CCOC(=O)c1cc(C)c(NC(=O)c2nc(N3CCC(O)CC3)ccc2C)c(C)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120015907A1,BrCCBr.C=CCNS(=O)(=O)c1ccccc1[N+](=O)[O-]>>C=CCN(CCBr)S(=O)(=O)c1ccccc1[N+](=O)[O-],,CN(C)C=O,,,,test
US20050171130A1,CC(C)O.Clc1cc(Cl)ncn1>>CC(C)Oc1cc(Cl)ncn1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US05416089,C[Mg]I.O=C1CCCc2c1cc1c3c(cccc23)CC1>>CC1(O)CCCc2c1cc1c3c(cccc23)CC1,,CCOCC,,,,test
US20070287701A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC1(O)CCN(C(=O)OCc2ccccc2)C1>>CC(C)(C)OC(=O)NCC1(O)CCN(C(=O)OCc2ccccc2)C1,,CCO,,,,test
US20070072866A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[Si](C)(C)CCOCn1nc(Cl)cc(-c2nc3ccc(C(F)(F)F)cc3n2COCC[Si](C)(C)C)c1=O>>C[Si](C)(C)CCOCn1nc(B(O)O)cc(-c2nc3ccc(C(F)(F)F)cc3n2COCC[Si](C)(C)C)c1=O,,CS(C)=O,,CC(=O)[O-].[K+],,test
US20090208485A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.FC(F)(F)c1ccnc(Br)c1>>CC(C)(C)OC(=O)N1CCC(O)(c2cc(C(F)(F)F)ccn2)CC1,,ClCCl,,[Li]CCCC,,test
US20110294812A1,CC(=O)Cc1ccnc(NC(=O)OC(C)(C)C)c1>>CC(O)Cc1ccnc(NC(=O)OC(C)(C)C)c1,,CO,,[BH4-].[Na+],,test
US20140275028A1,Nc1cc(OCc2ccc3ccccc3n2)ccc1NCc1ccc(C(F)(F)F)cc1.O=C1CC2(CCCC2)C(=O)O1>>O=C(O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2ccc(C(F)(F)F)cc2)CCCC1,,CC#N,,,,test
US20090099195A1,CC(C)(N)Cc1ccc(F)cc1.CCC(C)N1Cc2c(Cl)nc(Cl)nc2C1=O>>CCC(C)N1Cc2c(NC(C)(C)Cc3ccc(F)cc3)nc(Cl)nc2C1=O,,ClCCCl,,CCN(C(C)C)C(C)C,,test
US20070185103A1,COc1ccc2c(c1)C(Br)CC(C)(C)C2=O.[N-]=[N+]=N[Na]>>COc1ccc2c(c1)C(N=[N+]=[N-])CC(C)(C)C2=O,,CN(C)C=O,,,,test
US20020119981A1,CC(C)(C)OC(=O)N1CCC(CC(=O)N2CCN(C3c4ccc(Cl)cc4CCc4cc(Br)cnc43)CC2)CC1>>O=C(CC1CCNCC1)N1CCN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1,,C1COCCO1,CO,O=S(=O)(O)O,[Na+].[OH-],test
US07812045B2,O=[N+]([O-])c1ccc2c(cnn2CC(O)(Cn2cncn2)c2ccc(F)cc2F)c1>>Nc1ccc2c(c1)CNN2CC(O)(Cn1cncn1)c1ccc(F)cc1F,[Pd],CO,,[H][H],,test
US20120077799A1,Nc1ncccc1-c1ccc(C2CCCCC2)cc1.O=S(=O)(Cl)CCCl>>O=S1(=O)CCN2C=CC=C(c3ccc(C4CCCCC4)cc3)C2=N1,,C1CCOC1,,O,[H-].[Na+],test
US20100210636A1,CI.COc1ccc(CN2C(=O)NC(C[N+](=O)[O-])(C(F)(F)F)c3cc(Br)ccc32)cc1>>COc1ccc(CN2C(=O)N(C)C(C[N+](=O)[O-])(C(F)(F)F)c3cc(Br)ccc32)cc1,,CN(C)C=O,O,CCOC(C)=O,[H-].[Na+],test
US20120289474A1,CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3cc(-c4ccccc4)sc3c2=O)CC1.CC(C)(C)c1nnc(CCl)o1>>CC(C)(C)OC(=O)N1CCC(n2c(=O)c3sc(-c4ccccc4)cc3n(Cc3nnc(C(C)(C)C)o3)c2=O)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110230461A1,COC(=O)Cc1ccc(OC)cc1C#N>>COc1ccc(CC(=O)O)c(C#N)c1,,C1CCOC1,,O,,test
US20130303497A1,C#CCBr.O=C1NC(=O)C2C3CCC(C3)C12>>C#CCN1C(=O)C2C3CCC(C3)C2C1=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150152112A1,CC(C)(C)OC(=O)Nc1ccc(Cl)cc1-c1cc(=O)n2c(n1)CCC2C(=O)O.COC(=O)Nc1ccc(C(=O)CBr)cc1>>COC(=O)Nc1ccc(C(=O)COC(=O)C2CCc3nc(-c4cc(Cl)ccc4NC(=O)OC(C)(C)C)cc(=O)n32)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05817678,COC(=O)[C@@H]1CNC[C@H](C(=O)NCCc2cncn2Cc2ccc(C#N)cc2)C1.O=CCc1ccccc1>>COC(=O)[C@H]1C[C@@H](C(=O)NCCc2cncn2Cc2ccc(C#N)cc2)CN(CCc2ccccc2)C1,,CO,,[BH3-]C#N.[Na+],,test
US20100222299A1,CCC1Cc2cc(OCc3ccccc3)c(OC)cc2CN1.COc1cc(CCl)cc(OC)c1OC>>CCC1CC2CC(OCc3ccccc3)=C(OC)C=C2CN1Cc1cc(OC)c(OC)c(OC)c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,[Cl-].[NH4+],test
US06087390,CC(C)C1=CC2CC3(C=O)C4CCC(C)C4CC2(COC24OC5OC(C(O)C5O2)C4O[Si](C)(C)C(C)(C)C)C13C(=O)OC(c1ccccc1)c1ccccc1.CCCCCCCCCCBr>>CCCCCCCCCCOC1C2OC3(OCC45CC6C(C)CCC6C6(C=O)CC4C=C(C(C)C)C65C(=O)OC(c4ccccc4)c4ccccc4)OC2OC1C3O[Si](C)(C)C(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20110301181A1,BrBr.Cn1nc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1C(=O)O>>Cn1nc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c(Br)c1C(=O)O,,O,,,,test
US20080004271A1,N#Cc1c(Cl)nc(NC2CC2)nc1Cl.NC(=O)CS>>N#Cc1c(Cl)nc(NC2CC2)nc1SCC(N)=O,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20130096084A1,CC(C)(C)OC(=O)N1CC(N)CC(c2ccccc2)C1.O=C(O)c1ccc2c(c1)c(-c1ccncc1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1CC(NC(=O)c2ccc3c(c2)c(-c2ccncc2)nn3C(c2ccccc2)(c2ccccc2)c2ccccc2)CC(c2ccccc2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100016319A1,COc1ccc(N(NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc1C.Cl>>COc1ccc(NN)cc1C.Cl,,C1COCCO1,,,,test
US20060264415A1,COc1ccc(S(=O)(=O)Cl)cc1OC.Nc1ccc(OCCCNC(=O)COCc2ccc(F)cc2)cc1>>COc1ccc(S(=O)(=O)Nc2ccc(OCCCNC(=O)COCc3ccc(F)cc3)cc2)cc1OC,CN(C)c1ccncc1,c1ccncc1,,,,test
US20040053941A1,CCc1cnc(CC)c(NC(CC)CC)n1.O=C1CCC(=O)N1I>>CCc1nc(NC(CC)CC)c(CC)nc1I,,CN(C)C=O,,,,test
US20010039344A1,CS(=O)(=O)c1ccc(CC(=O)O)cc1.ICC1CCCC1>>CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)O)cc1,,C1CCOC1,CN1CCCN(C)C1=O,CC(C)NC(C)C,[Li]CCCC,test
US20130059835A1,COc1c(C(C)=O)cc(Cl)c(C)c1C1CNC(=O)CO1>>COc1c(C(C)O)cc(Cl)c(C)c1C1CNC(=O)CO1,,CO,,[BH4-].[Na+],,test
US20130046013A1,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCSC(CC)(CC)C(=O)Nc1ccc(O)c(C(=O)OC)c1>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCSC(CC)(CC)C(=O)Nc1ccc(O)c(C(=O)O)c1,,CO,,Cl,[Na+].[OH-],test
US20120101083A1,N#Cc1cc(-c2nc(-c3ccc4c(c3)CCNCC4)no2)ccc1N1CCC(F)C1.O=CC(O)CO>>N#Cc1cc(-c2nc(-c3ccc4c(c3)CCN(CC(O)CO)CC4)no2)ccc1N1CCC(F)C1,,C1CCOC1,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090275572A1,CN(Cc1cc2ccccc2n1C)C(=O)/C=C/c1ccc(N)nc1.O=C1OC(=O)c2ccccc21>>CN(Cc1cc2ccccc2n1C)C(=O)/C=C/c1ccc(N2C(=O)c3ccccc3C2=O)nc1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20080234255A1,C=CCNCC(C)C(=O)OC.O=[N+]([O-])c1cnc(Cl)nc1Cl>>C=CCN(CC(C)C(=O)OC)c1nc(Cl)ncc1[N+](=O)[O-],,CCOC(C)=O,O,O=C([O-])O.[K+],,test
US20050107362A1,O.O=C(CI)NC1c2ccccc2CC1NC(=O)c1cc2cc(Cl)ccc2[nH]1>>O=C(CO)NC1c2ccccc2CC1NC(=O)c1cc2cc(Cl)ccc2[nH]1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US04240820,CC(C)(C)c1coc(N)c1C#N.CCOCC(=O)Cl>>CCOCC(=O)Nc1occ(C(C)(C)C)c1C#N,,CN(C)C=O,,,,test
US20100233116A1,CCOC(=O)c1sc(N2CCN(Cc3ccc(F)cc3)C2=O)cc1C.NC[C@@H](N)Cc1ccccc1>>Cc1cc(N2CCN(Cc3ccc(F)cc3)C2=O)sc1C1=NC(Cc2ccccc2)CN1,,Cc1ccccc1,,C[Al](C)C,,test
US20130116234A1,COC(=O)c1c(C2CC2)nc2ccc(Cl)cc2c1-c1cccc(Cl)c1>>O=C(O)c1c(C2CC2)nc2ccc(Cl)cc2c1-c1cccc(Cl)c1,,CCO,,[Na+].[OH-],,test
US20140255381A1,NC1CN2CCC1CC2.O=C=NCc1ccccc1>>O=C(NCc1ccccc1)NC1CN2CCC1CC2,CCN(CC)CC,CN(C)C=O,,Cl,,test
US20110046108A1,CI.Clc1nccc(Nc2c(Cl)ccc3c2OCO3)n1>>CN(c1ccnc(Cl)n1)c1c(Cl)ccc2c1OCO2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140249104A1,COc1cnc2c(=O)[nH]ccc2c1.O=P(Cl)(Cl)Cl>>COc1cnc2c(Cl)nccc2c1,,CC#N,,,,test
US20160158207A1,CC(=O)N1CCc2c(c(N3CCCc4ccc(OC(F)(F)F)cc43)nn2[C@H]2CCOC2)C1.O=C1CCC(=O)N1Br>>CC(=O)N1CCc2c(c(N3CCCc4cc(Br)c(OC(F)(F)F)cc43)nn2[C@H]2CCOC2)C1,,ClCCl,,O,,test
US20120077799A1,Nc1nccnc1Cl.OB(O)c1ccc(OC2CCCCC2)nc1>>Nc1nccnc1-c1ccc(OC2CCCCC2)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US20130310405A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c5cc(-c6cccc(C#N)c6)ccc5nn4cc3-c3ccccc3)cc2)CCC1>>N#Cc1cccc(-c2ccc3nn4cc(-c5ccccc5)c(-c5ccc(C6(N)CCC6)cc5)nc4c3c2)c1,,C1COCCO1,Cl,,,test
US05877196,O=C1c2ccccc2C(=O)N1CCCCOc1ccc(-c2ccncn2)cc1>>NCCCCOc1ccc(-c2ccncn2)cc1,,CCO,,NN,,test
US06613760B1,C=O.CCOC(=O)c1cc2cc(O)ccc2n1Cc1ccc(Cl)c(Cl)c1.CNC>>CCOC(=O)c1cc2c(CN(C)C)c(O)ccc2n1Cc1ccc(Cl)c(Cl)c1,,CCO,,,,test
US06350749B1,Cc1ccccc1C1CC(=O)c2c(C)c[nH]c2C1.Cl.N=C(N)NN>>Cc1ccccc1C1CC(=NNC(=N)N)c2c(C)c[nH]c2C1.Cl,,CCO,,Cl,O,test
US05093364,O=c1[nH]c2cc(F)ccc2c(=O)o1.Oc1ccccc1>>Nc1cc(F)ccc1C(=O)Oc1ccccc1,,CCOC(C)=O,,C1CCOC1,[Na+].[OH-],test
US20050054628A1,CC(C)(C)OC(=O)N1CCC(c2ccc(Br)cc2)(C(COCC[Si](C)(C)C)Oc2nc3cc(Cl)c(Cl)cc3[nH]2)CC1.N#Cc1cccc(B(O)O)c1>>CC(C)(C)OC(=O)N1CCC(c2ccc(-c3cccc(C#N)c3)cc2)(C(COCC[Si](C)(C)C)Oc2nc3cc(Cl)c(Cl)cc3[nH]2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,CCOC(C)=O,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US04954501,CC1CC(=O)NN=C1c1ccc(NCCN)c([N+](=O)[O-])c1>>CC1CC(=O)NN=C1c1ccc(NCCN)c(N)c1,[Pd],CO,,[H][H],,test
US04822805,CNc1cc(OC)c(-c2nc(C)c(-c3cccnc3)[nH]2)cc1Cl>>CNc1ccc(-c2nc(C)c(-c3cccnc3)[nH]2)c(OC)c1,[Pd],CCN(CC)CC,CO,[H][H],,test
US20150111870A1,COC(=O)c1cccc(C)c1N.O=C1CCC(=O)N1Br>>COC(=O)c1cc(Br)cc(C)c1N,,O,,ClCCl,,test
US05663212,CC(=O)Cl.Cc1ccc(O)c(-n2nc3ccccc3n2)c1>>CC(=O)Oc1ccc(C)cc1-n1nc2ccccc2n1,,C1CCOC1,,CCN(CC)CC,O,test
US20140037564A1,Nc1cc(Cl)ccc1S.O=Cc1cc(Br)c(O)c(Br)c1>>Oc1c(Br)cc(-c2nc3cc(Cl)ccc3s2)cc1Br,,CN(C)C=O,,,,test
US20090162283A1,Brc1ccc2[nH]c(-c3ccc(-c4cnco4)cc3)nc2c1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)n1c(-c2ccc(-c3cnco3)cc2)nc2cc(Br)ccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160152543A1,COC(=O)C(OC(C)(C)C)c1c(C(F)(F)F)ccc(O)c1-c1ccc2c(c1)CCCO2.O=C1CCC(=O)N1Br>>COC(=O)C(OC(C)(C)C)c1c(C(F)(F)F)cc(Br)c(O)c1-c1ccc2c(c1)CCCO2,,ClCCl,,CC(C)NC(C)C,,test
US20100197683A1,CCCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(C2CCOC(C)(C)C2)c2ncnn12.O=C([O-])O.[NH3+]O>>CCCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(C2CCOC(C)(C)C2)c2ncnn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20100168430A1,CCC(=O)C(=O)Cl.O=C(Nc1ccc(Oc2ccnc3[nH]ncc23)cc1)Nc1ccc(Oc2ccc(F)cc2)c(C(F)(F)F)c1>>O=C1C(=O)N(c2ccc(Oc3ccc(F)cc3)c(C(F)(F)F)c2)C(=O)N1c1ccc(Oc2ccnc3[nH]ncc23)cc1,,C1CCOC1,ClCCl,,,test
US20080234262A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1CNCCO1>>CC1CN(C(=O)OC(C)(C)C)CCO1,,C1COCCO1,,[Na+].[OH-],,test
US20100048604A1,CC(C)C(O)c1cc(=O)oc2c3c4c(cc12)CCCN4CCC3>>CC(C)C(=O)c1cc(=O)oc2c3c4c(cc12)CCCN4CCC3,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20130059835A1,COc1c(C(C)Cl)cc(Cl)c(C)c1C1CN(C(=O)OC(C)(C)C)C1.Nc1ncnc2[nH]ccc(=O)c12>>COc1c(C(C)n2ccc(=O)c3c(N)ncnc32)cc(Cl)c(C)c1C1CN(C(=O)OC(C)(C)C)C1,,CN(C)C=O,O,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US05708033,CN.O=C(Cl)/C=C1\CCc2c(Cl)cc(F)cc21>>CNC(=O)/C=C1\CCc2c(Cl)cc(F)cc21,,ClCCl,,,,test
US05011947,CCOC(=O)C(C(C)(C)C)C(O)(c1ccc(F)cc1)c1ccc(F)cc1>>CCOC(=O)C(=C(c1ccc(F)cc1)c1ccc(F)cc1)C(C)(C)C,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US06100289,CC(C)(C)OC(=O)c1c(C(O)C2CN(C3C4CC5CC(C4)CC3C5)N(C(=O)OC(C)(C)C)C2=O)c2c(Cl)cc(Cl)cc2n1C(=O)OC(C)(C)C.CCO>>O=C1NCCC/C1=C\c1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12,,CCO,,O,[Li+].[OH-],test
US04140793,CC1C=CC(C)N1.COC(=O)CBr>>COC(=O)CN1[C@@H](C)C=C[C@@H]1C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20090221586A1,COC(=O)C(Cc1coc(-c2ccc(OC)c(OCc3ccccc3)c2)n1)C(=O)c1ncccc1C>>COc1ccc(-c2nc(CCC(=O)c3ncccc3C)co2)cc1O,,CCO,,Cl,,test
US06248739B1,Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CCl)ccc21.FC1(F)CCNCC1>>Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCC(F)(F)CC3)ccc21,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,O,test
US20120245144A1,BrP(Br)Br.Cc1nc(-c2cn3c(n2)-c2cc(C(C)O)c(F)cc2OCC3)n(C(C)C)n1>>Cc1nc(-c2cn3c(n2)-c2cc(C(C)Br)c(F)cc2OCC3)n(C(C)C)n1,,ClCCl,,O,O=C([O-])O.[Na+],test
US20140113901A1,CCOC(=O)c1ccc2nc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)n2n1.N>>NC(=O)c1ccc2nc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)n2n1,,CO,,,,test
US20130303533A1,CS(=O)(=O)CCn1ccc2c(Cl)nc(S(=O)(=O)c3ccc(F)cc3)nc21.Nc1cc[nH]n1>>CS(=O)(=O)CCn1ccc2c(Nc3cc[nH]n3)nc(S(=O)(=O)c3ccc(F)cc3)nc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20090156642A1,COC(=O)c1sc(Br)c(Br)c1C.Sc1ccccc1>>COC(=O)c1sc(Sc2ccccc2)c(Br)c1C,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04492792,CC(=N)N.COC(OC)C(C#N)C(OC)OC>>COC(OC)c1cnc(C)nc1N,,CO,,Cl,C[O-].[Na+],test
US20150210682A1,COCCOc1cc(CC(N)C(C)C)ccc1Cl.O=CO>>COCCOc1cc(CC(NC=O)C(C)C)ccc1Cl,,C1COCCO1,,,,test
US20030224283A1,C=C(C)C(=O)Cl.OCc1ccc2cc(O)ccc2c1>>C=C(C)C(=O)OCc1ccc2cc(O)ccc2c1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US05614631,C#CCCCCCCCCCC.O=Cc1cccc(Br)c1>>CCCCCCCCCCC#Cc1cccc(C=O)c1,[Cu]I,CCN(CC)CC,CCOC(C)=O,,,test
US20040147748A1,[H]/N=C(/C)NOC(=O)c1cnc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(C)(=O)=O)c(Cl)c2)cn1>>Cc1noc(-c2cnc(NC(=O)[C@H](CC3CCCC3)c3ccc(S(C)(=O)=O)c(Cl)c3)cn2)n1,,Cc1ccccc1,,,,test
US05856529,CCOC(=O)c1cccc(OCc2ccccc2)c1CCCO.CS(=O)(=O)Cl>>CCOC(=O)c1cccc(OCc2ccccc2)c1CCCOS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20100273779A1,Cc1nn(C)c(=O)cc1-c1ccc(O)cc1.ClCCCBr>>Cc1nn(C)c(=O)cc1-c1ccc(OCCCCl)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050245503A1,N[C@H]1c2ccccc2CC[C@H]1c1ccccc1.S=C(Cl)Cl>>S=C=N[C@H]1c2ccccc2CC[C@H]1c1ccccc1,,CCOC(C)=O,ClCCCl,Cl,O=C([O-])O.[Na+],test
US20150080412A1,CC(C)(C)c1ccc(CN(N)C(N)=O)cc1.CS(=O)(=O)O.O=C(O)COCc1ccc(Br)cc1>>CC(C)(C)c1ccc(CN(NC(=O)CCCc2ccc(Br)cc2)C(N)=O)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05571810,CN(C)C=O.O=C(Cc1ccc([N+](=O)[O-])cc1)c1ccc(F)cc1.O=P(Cl)(Cl)Cl>>O=CC(=C(Cl)c1ccc(F)cc1)c1ccc([N+](=O)[O-])cc1,,CC(Cl)Cl,,,,test
US05324747,CCCCCCCCCCCCCCCCCC(=O)Cl.Nc1cccc([N+](=O)[O-])c1>>CCCCCCCCCCCCCCCCCC(=O)Nc1cccc([N+](=O)[O-])c1,,ClCCl,,CCN(CC)CC,,test
US06051210,CC(=O)CNc1c(I)c(NCC(C)=O)c(I)c(C(=O)Cl)c1I.CC(C)COC(=O)CCCc1ccc(N)cc1>>CC(=O)CNc1c(I)c(NCC(C)=O)c(I)c(C(=O)Nc2ccc(CCCC(=O)O)cc2)c1I,,CC(=O)N(C)C,,,,test
US20140155419A1,Cc1ccc(C(N)c2ccccc2)c(Cl)c1.O=C(O)Cc1ccc(OCc2cccnc2)cc1>>Cc1ccc(C(NC(=O)Cc2ccc(OCc3cccnc3)cc2)c2ccccc2)c(Cl)c1,CN(C)c1ccncc1,CN(C)C=O,O,ClCCCl,On1nnc2ccccc21,test
US20020133023A1,N#CCCCCNc1ccccn1.NO>>N/C(CCCCNc1ccccn1)=N\O,,CO,,,,test
US20110230493A1,CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)CO2.O=S(=O)(N(c1ccc(Cl)cn1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCC2(C=C(OS(=O)(=O)C(F)(F)F)CO2)CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05206229,Cc1ccc(S(=O)(=O)Cl)cc1.OCCC1(O)CCCCC1>>Cc1ccc(S(=O)(=O)OCCC2(O)CCCCC2)cc1,,ClCCl,,c1ccncc1,,test
US20090036492A1,CCOc1ccc2ccccc2c1C=O.COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>CCOc1ccc2ccccc2c1CNC(=O)c1c(OC)cc(O)c2c1OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US04957928,COC(=O)CCN.Cc1ccc(S(=O)(=O)OCCC2COc3ccccc3C2)cc1.Cl>>COC(=O)CCNCCC1COc2ccccc2C1.Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20140094462A1,C=CC[C@@H](CC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1CN.C=CC[C@H](C)C(=O)O>>C=CC[C@@H](CC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1CNC(=O)[C@@H](C)CC=C,,ClCCl,,,,test
US05859251,C=Cc1ccncc1.CCCCCCCCCCC1(CCCCCCCCCC)c2cc(Br)ccc2-c2ccc(Br)cc21.CCN(CC)CC.Cc1ccccc1P(c1ccccc1C)c1ccccc1C>>CCCCCCCCCCC1(CCCCCCCCCC)c2cc(C=Cc3ccncc3)ccc2-c2ccc(C=Cc3ccncc3)cc21,[Pd],,,,,test
US05399578,CC(C)[C@H](NCc1ccc(-c2ccccc2C#N)cc1)C(=O)OCc1ccccc1.CCOC(=O)Cl>>CCOC(=O)N(Cc1ccc(-c2ccccc2C#N)cc1)[C@H](C(=O)OCc1ccccc1)C(C)C,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,,test
US20060173008A1,CCn1nc(-c2ccccc2)c(C(C)=O)c([N+](=O)[O-])c1=O.COc1cc(N)c2ncccc2c1>>CCn1nc(-c2ccccc2)c(C(C)=O)c(Nc2cc(OC)cc3cccnc23)c1=O,,CCO,,,,test
US20160152543A1,COC(=O)C(OC(C)(C)C)c1c(C)cc([N+](=O)[O-])c(O)c1-c1ccc2c(c1)CCCO2.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)C(OC(C)(C)C)c1c(C)cc([N+](=O)[O-])c(OS(=O)(=O)C(F)(F)F)c1-c1ccc2c(c1)CCCO2,,c1ccncc1,,,,test
US20100144760A1,COC(=O)c1nc(C)ccc1-n1nccn1>>Cc1ccc(-n2nccn2)c(C(=O)O)n1,,C1CCOC1,O,[Li+].[OH-],,test
US20120142653A1,C=C(C)[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>CC(C)[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,[Pd],CCOC(C)=O,CO,,,test
US05306718,CCOC(=O)C1=CC[C@@H]2CC[C@H]1N2C.[Li]C>>CC(=O)C1=CC[C@@H]2CC[C@H]1N2C,,C1CCOC1,,C[Si](C)(C)Cl,,test
US20040059109A1,C1COCCN1.COc1cc(C)cc(OC)c1OC(=O)C(Br)C(C)OC>>COc1cc(C)cc(OC)c1OC(=O)C(C(C)OC)N1CCOCC1,,CCOCC,,,,test
US20160185768A1,COC(=O)c1nc([C@@H]2CC[C@@H](C)NC2)sc1C.O=C(O)c1ccccc1-c1ncccn1>>COC(=O)c1nc([C@@H]2CC[C@@H](C)N(C(=O)c3ccccc3-c3ncccn3)C2)sc1C,,ClCCl,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06255496B1,CCCCCCCCCCCCNCCOc1ccc(CCC(OC)(OC)C(F)(F)F)cc1.CCOC(=O)CCC=O>>CCCCCCCCCCCCN(CCCC(=O)OCC)CCOc1ccc(CCC(OC)(OC)C(F)(F)F)cc1,,CCOCC,CO,[BH3-]C#N.[Na+],,test
US05733912,Cl.Clc1ncccc1C12CCCN1CCC2>>Cl.Clc1ncccc1C12CCCN1CCC2,,CCOCC,,,,test
US06436961B1,Nc1cccnc1-c1ccccc1>>NC1CCCNC1c1ccccc1,[Pt],O,,Cl,[H][H],test
US20120264737A1,C1CCNC1.Nc1cc(Cl)ncc1[N+](=O)[O-]>>Nc1cc(N2CCCC2)ncc1[N+](=O)[O-],,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04956462,COC(=O)c1cc(O)n2nc(C)nc2n1>>Cc1nc2nc(CO)cc(O)n2n1,,CCO,,[BH4-].[Na+],,test
US20130210818A1,O=C1COC(c2ccc(F)cc2)=N1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=S(=O)(Oc1coc(-c2ccc(F)cc2)n1)C(F)(F)F,,ClCCl,,Cc1cccc(C)n1,,test
US07319104B2,CCc1cnc(Cl)nc1.Oc1ccc(CCNCc2ccc(C(F)(F)F)cc2)cc1>>CCc1cnc(N(CCc2ccc(O)cc2)Cc2ccc(C(F)(F)F)cc2)nc1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20160152543A1,COC(=O)C(OC1CC1)c1c(C)c(N)cc(C2CC2)c1-c1ccc2c(c1)CCCO2.CS(=O)(=O)Cl>>COC(=O)C(OC1CC1)c1c(C)c(NS(C)(=O)=O)cc(C2CC2)c1-c1ccc2c(c1)CCCO2,,ClCCl,,c1ccncc1,,test
US06121202,CCc1c(Cl)nc(-c2ccc(C(F)(F)F)cc2)nc1Oc1csc(C(F)(F)F)c1>>CCc1cnc(-c2ccc(C(F)(F)F)cc2)nc1Oc1csc(C(F)(F)F)c1,[Pd],CCOC(C)=O,,CCN(CC)CC,CO,test
US20150322020A1,CCOc1c(OCC)c(=O)c1=O.COC(=O)[C@H](CN)NC(=O)c1ccc(Nc2nc(NC3(c4ccc(Cl)cc4)CC3)nc(OCC(F)(F)F)n2)cc1>>COC(=O)[C@H](CNc1c(OC)c(=O)c1=O)NC(=O)c1ccc(Nc2nc(NC3(c4ccc(Cl)cc4)CC3)nc(OCC(F)(F)F)n2)cc1,,CO,,,,test
US20160194302A1,CCOC(=O)Cn1ccnc1CCC(=O)O.CN(C)[C@H]1CCNC1>>CCOC(=O)Cn1ccnc1CCC(=O)N1CC[C@H](N(C)C)C1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140336388A1,CCn1nc(C2CCN(c3ccc(/N=C/c4ccc([N+](=O)[O-])o4)cc3F)CC2)oc1=O>>CCn1nc(C2CCN(c3ccc(NCc4ccc([N+](=O)[O-])o4)cc3F)CC2)oc1=O,CC(=O)O,CO,,[BH3-]C#N.[Na+],,test
US20120065196A1,COC(=O)[C@@H]1CC[C@@H](C(=O)NN)CC1.O=C(Cl)CCl>>COC(=O)[C@@H]1CC[C@@H](C(=O)NNC(=O)CCl)CC1,,ClCCl,,CN1CCOCC1,Cl,test
US20150329535A1,CC(C)(C)[Si](C)(C)O[C@@H](CNCCc1cccc(OCCCc2ccc(-c3ccccc3)c(NC(=O)O[C@H]3CN4CCC3CC4)c2)c1)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12>>CC(C)(C)[Si](C)(C)O[C@@H](CNCCc1cccc(OCCCc2ccc(-c3ccccc3)c(NC(=O)O[C@H]3CN4CCC3CC4)c2)c1)c1ccc(O)c2[nH]c(=O)ccc12,,CO,,,,test
US04299834,CCOc1cc(SC)ccc1C(=O)O.Cl.Nc1cncnc1N>>CCOc1cc(SC)ccc1-c1nc2ncncc2[nH]1.Cl,,O=P(Cl)(Cl)Cl,,,,test
US06211220B1,COc1ccc(CCl)cc1.Oc1ccccc1Br>>COc1ccc(COc2ccccc2Br)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20060252810A1,N#CC(=C(O)c1ccncc1)c1ccc(F)cc1>>O=C(Cc1ccc(F)cc1)c1ccncc1,,Br,,N,,test
US05376681,Cc1cc(C)c2c(c1C)OC(C)(CC(=O)N(C)C)C2>>Cc1cc(C)c2c(c1C)OC(C)(CCN(C)C)C2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100168094A1,C[C@H]1CCCN1.O=[N+]([O-])c1ccc(F)cc1C(F)(F)F>>C[C@H]1CCCN1c1ccc([N+](=O)[O-])c(C(F)(F)F)c1,,CC#N,,CCN(CC)CC,Cc1ccc(S(=O)(=O)O)cc1,test
US20150011533A1,CCOP(=O)(N[C@H]1CNCC[C@@H]1C1CC1)OCC.O=C(Nc1c[nH]c2ncc(Br)c(F)c12)c1cnn(Cc2ccccc2)c1>>N[C@H]1CN(c2c(Br)cnc3[nH]cc(NC(=O)c4cnn(Cc5ccccc5)c4)c23)CC[C@@H]1C1CC1,,CC(C)O,ClCCl,CCCCO,,test
US20010039344A1,COC(=O)Cc1ccc(SC)c(Br)c1.ICC1CCCC1>>COC(=O)C(CC1CCCC1)c1ccc(SC)c(Br)c1,,C1CCOC1,CN1CCCN(C)C1=O,CC(C)NC(C)C,[Li]CCCC,test
US20140206681A1,CCOc1cc(C(=O)Cl)c(F)cc1I.Nc1cc(C(F)(F)F)ccn1>>CCOc1cc(C(=O)Nc2cc(C(F)(F)F)ccn2)c(F)cc1I,CN(C)c1ccncc1,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090023729A1,Cc1cccc2cc(C=O)c(Cl)nc12.OCc1ccccc1>>Cc1cccc2cc(CO)c(OCc3ccccc3)nc12,,C1CCOC1,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20100137302A1,CC1(C)Cc2nc(N3CCOc4ccc(N)cc43)sc2C(=O)N1.Cn1cncc1C=O>>Cn1cncc1CNc1ccc2c(c1)N(c1nc3c(s1)C(=O)NC(C)(C)C3)CCO2,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US20060069140A1,CC(=O)c1c(C(F)(F)F)nn(-c2ccc(C)c(C)c2)c1O.COC(=O)c1ccc(C(=O)NN)cc1>>COC(=O)c1ccc(C(=O)NNC(C)=C2C(=O)N(c3ccc(C)c(C)c3)N=C2C(F)(F)F)cc1,,CN(C)C=O,,,,test
US20020045777A1,Br.CN(C(=O)OCc1ccccc1)[C@@H]1CC[C@@H](CCCCCBr)CC1>>Br.CN[C@@H]1CC[C@@H](CCCCCBr)CC1,,Br,,,,test
US08415386B2,O=C1c2nn(-c3ccc(Cl)cc3)cc2CN1c1ccc(F)nc1.c1ccc(CN2CC3CNCC3C2)cc1>>O=C1c2nn(-c3ccc(Cl)cc3)cc2CN1c1ccc(N2CC3CN(Cc4ccccc4)CC3C2)nc1,,CS(C)=O,,,,test
US06063789,CI.S=C=NCCc1cccs1>>CSC1=NCCc2sccc21.I,,CC(C)=O,,O=P(O)(O)O,,test
US20080058293A1,O=C(NCCc1ccccc1Cl)c1c(Cl)ccc2c1ccc[n+]2[O-].O=P(Cl)(Cl)Cl>>O=C(NCCc1ccccc1Cl)c1c(Cl)ccc2nc(Cl)ccc12,,ClCCl,,,,test
US20040063929A1,O=C(CC[C@H]1C(=O)N(c2ccc(F)cc2)[C@@H]1c1ccc(C[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1)c1ccc(F)cc1>>O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2ccc(C[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc2)N1c1ccc(F)cc1,,ClCCl,,,,test
US20090221555A1,CC(=O)N1CCCOc2ccc([N+](=O)[O-])cc21>>CC(=O)N1CCCOc2ccc(N)cc21,[Pd],CCO,,,,test
US04496568,Cc1ccc(S(=O)(=O)N2CC(=O)c3sccc3C2)cc1>>Oc1cncc2ccsc12,,CC(C)(C)O,,Cl,CC(C)(C)[O-].[K+],test
US05441950,CC(C)(N)CN.O=C(Cl)OCc1ccccc1>>CC(C)(N)CNC(=O)OCc1ccccc1,,Cc1ccccc1,,,,test
US20080085890A1,C1CCOC1.CN(C)C=Cc1ccn(-c2ccsc2)c(=O)c1>>O=Cc1ccn(-c2ccsc2)c(=O)c1,,C1CCOC1,,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20060074096A1,Cn1c(-c2ccnc(Nc3ccccc3)n2)cnc1CC(C)(C)O>>CC(C)=Cc1ncc(-c2ccnc(Nc3ccccc3)n2)n1C,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20080085890A1,COC=C1C(=O)NC(=O)c2ccc(Br)cc21.NCc1cc(O)ccc1O>>O=C1NC(=O)c2ccc(Br)cc2/C1=C/NCc1cc(O)ccc1O,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20120214993A1,Brc1c2ccccc2cc2ccccc12.Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1.c1ccc(-c2ncnc(-c3ccccc3)n2)cc1>>c1ccc(-c2nc(-c3ccccc3)nc(-c3cc(-c4c5ccccc5cc5ccccc45)cc(-c4c5ccccc5cc5ccccc45)c3)n2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,,[Na+].[OH-],,test
US20040029874A1,N#Cc1cc(Cl)ccn1.O=C(Nc1ccc(Cl)cn1)c1ccccc1NCC1CCNCC1>>N#Cc1cc(N2CCC(CNc3ccccc3C(=O)Nc3ccc(Cl)cn3)CC2)ccn1,,CCO,,CCN(CC)CC,,test
US20160145247A1,COC(=O)Cc1ccccc1OCc1cc(Cl)ccn1.NCc1cccc(B(O)O)c1F>>NCc1cccc(-c2ccnc(COc3ccccc3CC(=O)O)c2)c1F,,CN(C)C=O,,Cl,,test
US05972979,CC(=O)N1CCc2cc(O)c(Br)cc21.OCC1=CCC2(CC1)OCCO2>>CC(=O)N1CCc2cc(OCC3=CCC4(CC3)OCCO4)c(Br)cc21,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04894369,BrCC1CC1.CC(=O)O[C@H]1C[C@@H]2CC[C@H]3[C@@H]4C[C@H](N5CCCC5)[C@H](OC(C)=O)[C@@]4(C)CC[C@@H]3[C@@]2(C)C[C@@H]1N1CCOCC1>>CC(=O)O[C@H]1C[C@H]2CC[C@@H]3[C@H](CC[C@]4(C)[C@@H](OC(C)=O)[C@H]([N+]5(CC6CC6)CCCC5)C[C@@H]34)[C@@]2(C)C[C@@H]1N1CCOCC1.[Br-],,CC#N,,,,test
US04174401,CSC(=N)NC(c1ccccc1)c1ccccc1.I.NCCCN>>I.c1ccc(C(NC2=NCCCN2)c2ccccc2)cc1,,Clc1ccccc1Cl,,,,test
US20090076002A1,Cc1cc([N+](=O)[O-])ccc1OC1CC2CCC(C1)N2C>>Cc1cc(N)ccc1OC1CC2CCC(C1)N2C,[Pd],CO,,,,test
US20090281114A1,COc1cncnc1N1CCN(CCCc2c[nH]c3ccc([N+](=O)[O-])cc23)CC1>>COc1cncnc1N1CCN(CCCc2c[nH]c3ccc(N)cc23)CC1,[Pd],C1CCOC1,CCO,,,test
US20080269218A1,COCOc1cc(OCOC)c(C(C)C)cc1-c1nnc(S(C)(=O)=O)n1-c1ccc(CN2CCOCC2)cc1>>COCOc1cc(OCOC)c(C(C)C)cc1-c1n[nH]c(=O)n1-c1ccc(CN2CCOCC2)cc1,,CS(C)=O,,[Na+].[OH-],,test
US03940394,CCOC(=O)CSc1nc(Cl)cc(Cl)n1.Nc1ccc(Cl)cc1>>CCOC(=O)CSc1nc(Cl)cc(Nc2ccc(Cl)cc2)n1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20110301155A1,Cc1ccc(Nc2nn(COCC[Si](C)(C)C)c3ccc(-c4ncccc4Cl)cc23)nn1>>Cc1ccc(Nc2n[nH]c3ccc(-c4ncccc4Cl)cc23)nn1,,CCO,,Cl,O=C([O-])O.[Na+],test
US20160221973A1,COC(=O)c1ccc2c(c1)OC[C@H](c1ccccc1)N(c1ccccc1)C2.NO>>O=C(NO)c1ccc2c(c1)OC[C@H](c1ccccc1)N(c1ccccc1)C2,,C1CCOC1,CO,[Na+].[OH-],,test
US05849736,CC(C)(C)OC(=O)N1CCC(COc2ccc(C=O)cc2)CC1.NO>>CC(C)(C)OC(=O)N1CCC(COc2ccc(C=NO)cc2)CC1,,CO,c1ccncc1,Cl,,test
US04572912,C=CC(=O)OCC.CC(=O)Oc1c(C)c(C)c2c(c1C)CCC(C)(COc1ccc(N)cc1)O2.Cl>>CCOC(=O)C(Cl)Cc1ccc(OCC2(C)CCc3c(C)c(OC(C)=O)c(C)c(C)c3O2)cc1,,CC(C)=O,O,O=N[O-].[Na+],,test
US20060173018A1,O=C(n1ccnc1)n1ccnc1.OCC1CCCCO1>>O=C(OCC1CCCCO1)n1ccnc1,,ClCCl,,,,test
US20130345194A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NS(=O)(=O)N1CCN(c2ncnc3[nH]ccc23)CC12CC2>>CC(C)(C)OC(=O)NS(=O)(=O)N1CCN(c2ncnc3c2ccn3C(=O)OC(C)(C)C)CC12CC2,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100197591A1,CCOC(=O)CCN(C(=O)CC#N)c1ccc(C2(C#N)CCC2)cc1>>N#CC1=C(O)CCN(c2ccc(C3(C#N)CCC3)cc2)C1=O,,CO,,C1CCC2=NCCCN2CC1,,test
US20020156105A1,O=C1CCCCC1.c1cscn1>>OC1(c2nccs2)CCCCC1,,CCCCCC,CCOCC,[Li]CCCC,[Cl-].[NH4+],test
US20140206663A1,CC1C(=O)N(COCC[Si](C)(C)C)N=C2COc3cc(C(F)(F)F)c(NC4(C)CN(C(=O)OC(C)(C)C)C4)cc3N21>>C[C@@H]1C(=O)NN=C2COc3cc(C(F)(F)F)c(NC4(C)CN(C(=O)OC(C)(C)C)C4)cc3N21,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20070244132A1,CC(C)(C)OC(=O)NCCn1ccc2ncnc(Cl)c21.Nc1ccc(Oc2cccc(C(F)(F)F)c2)c(Cl)c1>>CC(C)(C)OC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(C(F)(F)F)c4)c(Cl)c3)c21,,CC(C)O,,O=C([O-])O.[Na+],,test
US20100120714A1,CC(C)c1nsc(Cl)n1.COC(=O)NCc1cc(-c2cc[nH]n2)ccc1Cl>>COC(=O)NCc1cc(-c2ccn(-c3nc(C(C)C)ns3)n2)ccc1Cl,,CN1CCCC1=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050203160A1,Cn1nc(-c2ccc(OC(F)(F)F)cc2)cc1CC(=O)O>>Cn1nc(-c2ccc(OC(F)(F)F)cc2)cc1CCO,,C1CCOC1,C1CCOC1,,,test
US20080004302A1,CC(C)Cc1cc(N)[nH]n1.Clc1ccnc(NCc2cc(C3CC3)no2)n1>>CC(C)Cc1cc(Nc2ccnc(NCc3cc(C4CC4)no3)n2)[nH]n1,,CCO,,,,test
US04096267,BrCc1ccccc1.CC1Cc2cc(O)c(Cl)c(Cl)c2C1=O>>CC1Cc2cc(OCc3ccccc3)c(Cl)c(Cl)c2C1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110034439A1,COc1cc2nccc(Oc3ccc(N)cc3F)c2cc1C(=O)O.COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2cc1C(=O)OC(C)(C)C.O=C=NSC(=O)C(F)c1ccccc1>>COc1cc2nccc(Oc3cccc(NC(=S)NC(=O)Cc4ccccc4F)c3F)c2cc1C(=O)O,,CCO,Cc1ccccc1,CC(=O)N(C)C,,test
US08859509B2,C#CCBr.[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCO>>C#CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-],,CN(C)C=O,ClCCl,CO,[H-].[Na+],test
US20030018029A1,C1COCCN1.O=Cc1cc(Br)cs1>>Brc1csc(CN2CCOCC2)c1,,CC(=O)O,CCO,[BH3-]C#N.[Na+],,test
US20120088750A1,CC(=O)Cl.CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)OCC)CC4)nc3)cc(C#N)c2s1.NO>>CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)OCC)CC4)nc3)cc(-c3noc(C)n3)c2s1,,CCOC(C)=O,c1ccncc1,Cl,,test
US20080234349A1,COC(=O)/C=C/c1ccc2c(ccn2S(=O)(=O)c2ccc(Br)s2)c1.OB(O)c1cccc(OC(F)(F)F)c1>>COC(=O)/C=C/c1ccc2c(ccn2S(=O)(=O)c2ccc(-c3cccc(OC(F)(F)F)c3)s2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US06713471B1,NNc1cc(Br)ccc1SCCCCl.O=C1CCNCC1>>ClCCCSc1ccc(Br)c2c3c([nH]c12)CCNC3,,CCO,,Cl,O,test
US20070155721A1,COc1cccc2occ(C=O)c12>>COc1cccc2occ(CO)c12,,CO,,[BH4-].[Na+],,test
US20150166575A1,Cc1ccn2cc(-c3cc4ccc(N5CCN(C(=O)OC(C)(C)C)CC5)nc4oc3=O)nc2c1.Cl>>Cc1ccn2cc(-c3cc4ccc(N5CCNCC5)nc4oc3=O)nc2c1.Cl,,C1COCCO1,ClCCl,,,test
US20110053911A1,COc1ccc(CN2Cc3c(-c4ccc(C#N)cc4)nc4cccc(n34)C2=O)c(OC)c1.O=[Pt]=O>>COc1ccc(CN2Cc3c(-c4ccc(C=O)cc4)nc4cccc(n34)C2=O)c(OC)c1,O=[Pt]=O,C1CCOC1,,O=CO,,test
US05075502,CC(=O)Nc1c(I)c(C(=O)NCC(O)CC(O)CO)c(I)c(C(=O)NCC(O)CC(O)CO)c1I.OCCCl>>CC(=O)N(CCO)c1c(I)c(C(=O)NCC(O)CC(O)CO)c(I)c(C(=O)NCC(O)CC(O)CO)c1I,,[Na+],[OH-],O=S(=O)(O)O,,test
US20120196851A1,CC(=O)N1CCNCC1.O=C(O)[C@@H]1CC[C@@H](CN2C(=O)Cc3ccccc3C2=O)CC1>>CC(=O)N1CCN(C(=O)[C@@H]2CC[C@@H](CN3C(=O)Cc4ccccc4C3=O)CC2)CC1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160229837A1,Clc1ncc(Cl)c(Cl)n1.N#Cc1ccc(N2CCC(N)CC2)nc1>>N#Cc1ccc(N2CCC(Nc3nc(Cl)ncc3Cl)CC2)nc1,,CC(C)O,,CCN(CC)CC,,test
US20140005132A1,CC(C)(C)[Si](O[C@H]1CC[C@@]2(C)C(=CCC3C2CC[C@@]2(C)C3CC[C@@H]2n2cc(-c3ccccc3)nn2)C1)(c1ccccc1)c1ccccc1>>C[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2n1cc(-c2ccccc2)nn1,,CO,Cl,,,test
US20100179137A1,CCOC(=O)CCCCCCn1c(CBr)c(Br)cc(Br)c1=O.O>>O=C(O)CCCCCCn1c(CO)c(Br)cc(Br)c1=O,,O,,C1COCCO1,,test
US04826836,CC(=O)C(C)(C)Oc1cccc(C(F)(F)F)c1.OC(O)CCCl>>CC(C)(Oc1cccc(C(F)(F)F)c1)C1(C)OCC(CCl)O1,,Cc1ccccc1,,O,,test
US20110009396A1,CC1=C2[C@@H]3OC(=O)C(CN4CCN(Cc5ccccc5)CC4)C3(O)CC[C@@]2(C)CCC1>>CC1=C2[C@H](O)C(O)(C(CO)CN3CCN(Cc4ccccc4)CC3)CC[C@@]2(C)CCC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070161673A1,CCNC(=O)c1cc(F)c(C)c(-c2ccc(C(=O)c3ccc(OC)cc3)c(Cl)n2)c1.NN>>CCNC(=O)c1cc(F)c(C)c(-c2ccc3c(-c4ccc(OC)cc4)n[nH]c3n2)c1,,C1CCOC1,,O,,test
US20060063934A1,CS(=O)(=O)O.Nc1cc(-c2cn(-c3ccc4nncn4n3)nc2-c2ccc(F)cc2)ccn1>>CS(=O)(=O)O.Nc1cc(-c2cn(-c3ccc4nncn4n3)nc2-c2ccc(F)cc2)ccn1,,CCOC(C)=O,,CS(C)=O,,test
US20150210688A1,CC(C)(C)OC(=O)N1CCC(c2ccc(Cl)cc2)CC1>>Clc1ccc(C2CCNCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090099161A1,COCc1nc2c(N)nc3cc(CCS(C)(=O)=O)ccc3c2n1CC(C)(C)O>>CC(C)(O)Cn1c(CO)nc2c(N)nc3cc(CCS(C)(=O)=O)ccc3c21,,ClCCl,,,,test
US20090286812A1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.N#Cc1ncccc1O>>CC(C)(C)OC(=O)N1CCC(n2ncc3c(Oc4cccnc4C#N)ncnc32)CC1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US04889553,CNc1nc(S(=O)(=O)Cl)nn1C(C)=O.Nc1c(Cl)cccc1Cl>>CNc1nc(S(=O)(=O)Nc2c(Cl)cccc2Cl)n[nH]1,,c1ccncc1,,,,test
US20050187298A1,COC(=O)Cc1ccc(C#Cc2cc(C(C)(C)C)c(OC(C)C)c(C=O)c2C)cc1>>COC(=O)Cc1ccc(C#Cc2cc(C(C)(C)C)c(OC(C)C)c(CO)c2C)cc1,,CO,,[BH4-].[Na+],,test
US04703049,CCc1c(OC)nc2nc(C(=O)NN)cn2c1C.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCc1c(OC)nc2nc(-c3nnc(C(F)(F)F)o3)cn2c1C,,ClCCl,,CCN(CC)CC,,test
US05599770,COc1cc(OC)nc(Cl)n1.OCc1ccccc1>>COc1cc(OC)nc(OCc2ccccc2)n1,,CCCCCC,CN(C)C=O,[H-].[Na+],,test
US05639779,CCS(=O)(=O)C=Cc1ccc2[nH]cc(C[C@H]3CCCN3C(=O)OCc3ccccc3)c2c1>>CCS(=O)(=O)CCc1ccc2[nH]cc(C[C@H]3CCCN3)c2c1,[Pd],CCO,,,,test
US20120214735A1,CCOC(=O)Cc1ccc(S(=O)(=O)C2CC2)cc1.Cc1ccc(S(=O)(=O)N=[N+]=[N-])cc1>>CCOC(=O)C(=[N+]=[N-])c1ccc(S(=O)(=O)C2CC2)cc1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US05516774,O=C(Cl)c1ccc([N+](=O)[O-])cc1.c1ccc2c(c1)NCCc1nncn1-2>>O=C(c1ccc([N+](=O)[O-])cc1)N1CCc2nncn2-c2ccccc21,,ClCCl,,CCN(CC)CC,,test
US20010037030A1,NC12CC1CC1CNCC12.Nc1c(F)c(F)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1>>Nc1c(F)c(N2CC3CC4CC4(N)C3C2)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1,,CC#N,,CCN(CC)CC,,test
US20080255149A1,Cc1ccc(Cl)cc1N1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2Cl)NC(=O)OC(C)(C)C)CC1>>Cc1ccc(Cl)cc1N1CCN(C(=O)[C@H](N)Cc2ccc(Cl)cc2Cl)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040214953A1,CCCCCCCCCCCCCCCCCCN(C)C.Cl>>CCCCCCCCCCCCCCCCCCN(C)C.Cl,,CCO,,O,,test
US04521426,Nc1cnc(Oc2ccc(Cl)c3c2CCCC3)c(Cl)c1.O=C=NC(=O)c1c(F)cccc1Cl>>O=C(NC(=O)c1c(F)cccc1Cl)Nc1cnc(Oc2ccc(Cl)c3c2CCCC3)c(Cl)c1,,Cc1ccccc1,,,,test
US20100261728A1,O=C=Nc1ccc(F)cc1.c1ccc2c(c1)CCNC2c1c[nH]c2ccccc12>>O=C(Nc1ccc(F)cc1)N1CCc2ccccc2C1c1c[nH]c2ccccc12,,CN(C)C=O,ClCCl,,,test
US20080269210A1,C[C@H]1COCCN1.Cc1csc2nc(Cl)nc(Cl)c12>>Cc1csc2nc(Cl)nc(N3CCOC[C@@H]3C)c12,,CO,,CCN(CC)CC,,test
US20090137804A1,CCNc1cc(Cl)ncn1.CN1CCN(c2ccc(N)cc2)CC1>>CCNc1cc(Nc2ccc(N3CCN(C)CC3)cc2)ncn1,,CC(=O)O,O,,,test
US04914207,COc1ccccc1-c1nc(CCl)cs1.Cc1c[nH]cn1>>COc1ccccc1-c1nc(Cn2cncc2C)cs1,,C1CCOC1,,O,[H-].[Na+],test
US20050085483A1,COC(=O)C(C)(CN)NC(=O)OCc1ccccc1.O=S(=O)(Cl)c1ccc(Cl)cc1Cl>>COC(=O)C(C)(CNS(=O)(=O)c1ccc(Cl)cc1Cl)NC(=O)OCc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040236115A1,CC(C)(C)N.Cc1cc2c(s1)C([Si](C)(C)Cl)c1ccccc1-2>>Cc1cc2c(s1)C([Si](C)(C)NC(C)(C)C)c1ccccc1-2,,CCCCCC,CCOCC,[Li]CCCC,,test
US20160237091A1,Cc1cc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3cc4[nH]c(=O)c(C(CO)c5ccccc5)cc4cc23)ccn1>>Cc1cc(-c2n[nH]c3cc4[nH]c(=O)c(C(CO)c5ccccc5)cc4cc23)ccn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090029965A1,CC(C)(C)OC(=O)N1CCC(CNC2CC2)CC1.Cc1cc(C(=O)N2Cc3cnn(C)c3Nc3ccccc32)ccc1CCC(=O)O>>Cc1cc(C(=O)N2Cc3cnn(C)c3Nc3ccccc32)ccc1CCC(=O)N(CC1CCN(C(=O)OC(C)(C)C)CC1)C1CC1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US04174958,CNCCO.O=C=Nc1ccc([N+](=O)[O-])c(C(F)(F)F)c1>>CN(CCO)C(=O)Nc1ccc([N+](=O)[O-])c(C(F)(F)F)c1,,C1CCOC1,,,,test
US20110319394A1,Nc1ccc(N2CCn3c2nc2ccccc23)cc1.O=[N+]([O-])c1cccnc1Cl>>O=[N+]([O-])c1cccnc1Nc1ccc(N2CCn3c2nc2ccccc23)cc1,,CN1CCCC1=O,O,,,test
US20030166639A1,CC(C)c1ccc(-c2cccc(C(=O)CC(=O)Nc3cc(C(F)(F)F)c(OCC(F)(F)F)cc3NC(=O)OC(C)(C)C)c2)cn1>>CC(C)c1ccc(-c2cccc(C3=Nc4cc(OCC(F)(F)F)c(C(F)(F)F)cc4NC(=O)C3)c2)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080221134A1,C#CCn1c(=O)c2c(nc(C#Cc3cccc(OC)c3)n2C)n(C)c1=O>>C#CCn1c(=O)c2c(nc(C#Cc3cccc(O)c3)n2C)n(C)c1=O,,ClCCl,,BrB(Br)Br,,test
US04772601,C#CCN1C(=O)CCC1C(=O)OC.N>>C#CCN1C(=O)CCC1C(N)=O,,CO,,,,test
US20090105211A1,Cc1ccc(Br)cc1NC(=O)c1ccc(Nc2nc(-c3ccccc3)c3ccccc3n2)cc1.OB(O)n1cccn1>>Cc1ccc(-c2ccn[nH]2)cc1NC(=O)c1ccc(Nc2nc(-c3ccccc3)c3ccccc3n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20070276000A1,COc1ccc2c(Oc3ccc(/C=C/C(=O)O)cc3)c(-c3ccccc3)c(C3CC3)cc2c1>>O=C(O)/C=C/c1ccc(Oc2c(-c3ccccc3)c(C3CC3)cc3cc(O)ccc23)cc1,,ClCCl,,BrB(Br)Br,,test
US20020037907A1,CC(=O)Oc1ccc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c([N+](=O)[O-])c1>>CC(=O)Oc1ccc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(N)c1,[Ni],C1CCOC1,,[H][H],,test
US04966905,CC1=CC(=O)C(C)(C)O1.O=Cc1cccs1>>CC1(C)OC(C=Cc2cccs2)=CC1=O,,CCO,,[Na+].[OH-],,test
US20090264416A1,CC(C)(C)NC(=O)c1cccc(CN2CCN(C(=O)c3cnc(NC(=O)OC(C)(C)C)cn3)CC2)c1>>CC(C)(C)NC(=O)c1cccc(CN2CCN(C(=O)c3cnc(N)cn3)CC2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120122843A1,C=O.CC1NCC(CC(F)(F)F)Oc2nc(Cl)ccc21>>CC1c2ccc(Cl)nc2OC(CC(F)(F)F)CN1C,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090143372A1,CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4csc(C=O)c4)cc23)CC1.C[C@H]1CCCN1C>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4csc(CN5CCC[C@@H]5C)c4)cc23)CC1,CC(=O)O,CS(C)=O,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130072473A1,CCN(CC)CC.CCO.N#CCc1nc2ccccc2s1.[S]>>Nc1sc2c(c1-c1nc3ccccc3s1)CCCC2,,CCO,,,,test
US20080139558A1,CC(=O)c1cccc(Cl)c1.Cc1ncsc1C(=O)Cl>>Cc1ncsc1C(=O)CC(=O)c1cccc(Cl)c1,,C1CCOC1,ClCCl,Cl,CC(C)[N-]C(C)C.[Li+],test
US20060194782A1,CCc1cccc(C)c1CNc1nc(Br)cc(NC)c1N.COC(C)(OC)OC>>CCc1cccc(C)c1CNc1nc(Br)cc2c1nc(C)n2C,,CCO,,O,O=C([O-])O.[Na+],test
US20060183909A1,O=C(OCc1ccccc1)c1ccc2cccc(OCc3ccccc3)c2n1.O=C1C(Br)=CC(Br)(Br)C=C1Br>>O=C(OCc1ccccc1)c1ccc2c(Br)ccc(OCc3ccccc3)c2n1,,ClCCl,,,,test
US20150225361A1,COC(=O)C[C@@H]1COc2cc(O)ccc21>>O=C(O)C[C@@H]1COc2cc(O)ccc21,,CO,,Cl,[Na+].[OH-],test
US20140018319A1,COc1ccc(CN(c2nc(Nc3cccc(C#N)n3)nn3c(C#N)cnc23)C2CC2)cc1>>N#Cc1cccc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)n1,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US06166006,CI.O=C(C=Cc1cccc(-c2ccccc2)c1)Nc1ccc(CN2CCCCC2)cc1>>C[N+]1(Cc2ccc(NC(=O)C=Cc3cccc(-c4ccccc4)c3)cc2)CCCCC1.[I-],,CN(C)C=O,,,,test
US20090030018A1,CCOC(=O)c1ccc(Nc2cccc(CO)c2)c(N)c1.CCOC(OCC)OCC>>CCOC(=O)c1ccc2c(c1)ncn2-c1cccc(CO)c1,,C1CCOC1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090042925A1,CC(C)C(=O)OC(=O)C(C)C.Cc1c(C)n2nnnc2c2nc(CCl)n(CCCCN)c12>>Cc1c(C)n2nnnc2c2nc(CCl)n(CCCCNC(=O)C(C)C)c12,,ClCCl,,CCN(CC)CC,Cl,test
US20110152245A1,CC(C)(C)OC(=O)N1CCO[C@H](c2ccc(Br)cc2)C1.CN(C)C=O>>CC(C)(C)OC(=O)N1CCO[C@H](c2ccc(C=O)cc2)C1,,C1CCOC1,,[Li]CCCC,,test
US20080262055A1,N#Cc1ccc(N)c(Cl)c1>>NCc1ccc(N)c(Cl)c1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20120035237A1,BrCC1CCCCC1.O=C(Nc1c(F)cccc1F)c1ccn(Cc2cc(Cl)ccc2O)n1>>O=C(Nc1c(F)cccc1F)c1ccn(Cc2cc(Cl)ccc2OCC2CCCCC2)n1,,CN(C)C=O,CO,O=C([O-])[O-].[K+].[K+],,test
US20140061620A1,Brc1cc(-c2nc3ccccc3o2)cc(-c2nc3ccccc3o2)c1.CC1(C)OB(c2cc(-c3nc4ccccc4o3)cc(-c3nc4ccccc4o3)c2)OC1(C)C>>c1ccc2oc(-c3cc(-c4cc(-c5nc6ccccc6o5)cc(-c5nc6ccccc6o5)c4)cc(-c4nc5ccccc5o4)c3)nc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20120245182A1,CCN1CCN(c2ccc(Nc3cc(NC)ncn3)cc2)CC1.COc1cc(OC)c(Cl)c(N=C=O)c1Cl>>CCN1CCN(c2ccc(Nc3cc(N(C)C(=O)Nc4c(Cl)c(OC)cc(OC)c4Cl)ncn3)cc2)CC1,,Cc1ccccc1,,,,test
US20140170110A1,N#CCC(=O)ON1C(=O)CCC1=O.O=c1[nH]cccc1Nc1ncc2[nH]c(=O)n([C@H]3CCCNC3)c2n1>>N#CCC(=O)N1CCC[C@H](n2c(=O)[nH]c3cnc(Nc4ccc[nH]c4=O)nc32)C1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20140088101A1,CCOC(=O)CCCNC(=O)c1ncc2c(cc(-c3ccccc3)c(=O)n2Cc2ccccc2)c1O>>O=C(O)CCCNC(=O)c1ncc2c(cc(-c3ccccc3)c(=O)n2Cc2ccccc2)c1O,,CO,,C1CCOC1,[Na+].[OH-],test
US20130102576A1,CC(C)(C)OC(=O)CN1C(=O)c2ccc(CNS(C)(=O)=O)cc2C1=O>>CS(=O)(=O)NCc1ccc2c(c1)C(=O)N(CC(=O)O)C2=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US06380387B1,CI.Cn1c(=O)cc(C(F)(F)F)[nH]c1=O>>Cn1c(C(F)(F)F)cc(=O)n(C)c1=O,,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20020086996A1,CC(C)(C)OC(=O)N1CCN(c2nc(CCl)cs2)CC1.COC(=O)C1CCNCC1>>COC(=O)C1CCN(Cc2csc(N3CCN(C(=O)OC(C)(C)C)CC3)n2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100087487A1,OC1CCOCC1.Oc1ccc(Br)cc1Cl>>Clc1cc(Br)ccc1OC1CCOCC1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060009493A1,NNC(=O)Cc1ccc(O)c(Br)c1.O=C1Nc2ccccc2C1=O>>O=C(Cc1ccc(O)c(Br)c1)N/N=C1\C(=O)Nc2ccccc21,,CC(=O)O,,,,test
US20030145641A1,C=O.Cc1c[nH]nc1C>>Cc1cn(CO)nc1C,,CO,,,,test
US20120264737A1,CCc1cc(C2CC2)c(I)cc1C(=O)O.COC(=O)Cl>>CCc1cc(C2CC2)c(C(=O)OC)cc1C(=O)O,,C1CCOC1,CCOCC,[Li]CCCC,,test
US20120202785A1,C[C@H](Nc1ncnc2c1ncn2C1CCCCO1)C(=O)Nc1ccc(F)cc1N[C@@H]1CCCN(CCOC(=O)C(C)(C)C)C1>>C[C@H](Nc1ncnc2[nH]cnc12)c1nc2ccc(F)cc2n1[C@@H]1CCCN(CCO)C1,,Cl,,,,test
US04293557,O=C(CO)NCCCOc1cccc(CN2CCCCC2)c1.O=C(Cl)c1ccccc1>>O=C(COC(=O)c1ccccc1)NCCCOc1cccc(CN2CCCCC2)c1,,c1ccncc1,,,,test
US20100120801A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CN(C)CCn1cnc(-c2ccc(F)c(Cl)c2)c1>>CN(C)CCn1cc(-c2ccc(F)c(Cl)c2)nc1C1(O)CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,[Li]CCCC,,test
US04101543,CCO.Nc1ccc(C=CC(=O)O)cc1>>CCOC(=O)C=Cc1ccc(N)cc1,,O,,[Na+].[OH-],,test
US20070010671A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](CNC(=O)c2cccc([N+](=O)[O-])c2)CC1.Cl>>Cl.N[C@H]1CC[C@@H](CNC(=O)c2cccc([N+](=O)[O-])c2)CC1,,ClCCl,O=C(O)C(F)(F)F,CCOCC,,test
US20090275537A1,C=O.NC(Cc1cccc(F)c1)C(=O)O>>O=C(O)C1Cc2cc(F)ccc2CN1,,Cl,,,,test
US20050085508A1,C=CCBr.COC(=O)C1CCCCC1>>C=CCC1(C(=O)OC)CCCCC1,,CN(C)C=O,O,Cl,CC(C)(C)[O-].[K+],test
US06121182,C1=Cc2ccccc2C1.C[Si](C)(Cl)Cl>>C[Si](C)(Cl)C1C=Cc2ccccc21,,CCCCCC,,[Li]CCCC,,test
US20040122000A1,CC(C)CN(C[C@@H](O)[C@H](Cc1ccc(O)cc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc2c(c1)OCO2.O=[N+]([O-])c1ccc(Cl)nc1>>CC(C)CN(C[C@@H](O)[C@H](Cc1ccc(Oc2ccc([N+](=O)[O-])cn2)cc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc2c(c1)OCO2,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05631208,CCC(=O)O.Cc1c(C)c(C2CC(=O)C=C(O)C2)c(C)c2c1CC(C)(C)O2>>CCC(=O)C1=C(O)CC(c2c(C)c(C)c3c(c2C)OC(C)(C)C3)CC1=O,,Cc1ccccc1,,CN(C)c1ccccn1,,test
US20130317003A1,CC(=O)Cl.Ic1cn[nH]c1>>CC(=O)n1cc(I)cn1,,ClCCl,,CCN(CC)CC,O,test
US20160016908A1,COc1ccc2c(c1)[C@H](Nc1ccccc1)[C@@H](C)[C@H](C)N2C(C)=O>>CC(=O)N1c2ccc(O)cc2[C@H](Nc2ccccc2)[C@@H](C)[C@@H]1C,,ClCCl,,BrB(Br)Br,CO,test
US20110135668A1,CI.Clc1nc(Cl)c2c(Br)c[nH]c2n1>>Cc1c[nH]c2nc(Cl)nc(Cl)c12,,C1CCOC1,,[Li]CCCC,,test
US20110009390A1,O=C(Cl)C(=O)Cl.c1ccc(-c2cc3n(c2)CCCC3)cc1>>O=C(Cl)C(=O)c1c(-c2ccccc2)cc2n1CCCC2,,C1CCOC1,Cc1ccccc1,,,test
US20050080111A1,CCC(=O)C(=O)O.OCc1ccccc1>>CCC(=O)C(=O)OCc1ccccc1,,c1ccccc1,,O,,test
US05883049,CCOC(=O)CS.O=C1C2=CCCCN2C(=O)N1c1cc([N+](=O)[O-])c(F)cc1F>>CCOC(=O)CSc1cc(F)c(N2C(=O)C3=CCCCN3C2=O)cc1[N+](=O)[O-],,C1COCCO1,CCOC(C)=O,Cl,[H-].[Na+],test
US04602016,NC(=O)c1ccc(OCCCl)cc1.c1c[nH]cn1>>NC(=O)c1ccc(OCCn2ccnc2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04362728,CNC(=C[N+](=O)[O-])SC.NCCCSc1nccc(NC(N)=NCC(F)(F)F)n1>>CNC(=C[N+](=O)[O-])NCCCSc1nccc(NC(N)=NCC(F)(F)F)n1,,CC#N,,,,test
US20100261719A1,Cc1nnc(C#Cc2cc(C=O)c(N3C[C@H](C)O[C@H](C)C3)c(F)c2F)s1.O=C1CC(=O)NC(=O)N1>>Cc1nnc(C#Cc2cc3c(c(F)c2F)N2C[C@H](C)O[C@H](C)[C@H]2C2(C3)C(=O)NC(=O)NC2=O)s1,,CC(C)O,,,,test
US20080312270A1,CNc1nc2ccc(Oc3cc(Cl)c(CC(=O)OC)cc3OC)c([N+](=O)[O-])c2s1>>CNc1nc2ccc(Oc3cc(Cl)c(CC(=O)OC)cc3OC)c(N)c2s1,[Pd],CCOC(C)=O,CO,,,test
US20030045535A1,Cc1cc(Nc2ncnc3cnc(N4CC5C(N)C5C4)cc23)ccc1Oc1ccccc1.O=C(Cl)C1CC1>>Cc1cc(Nc2ncnc3cnc(N4CC5C(C4)C5NC(=O)C4CC4)cc23)ccc1Oc1ccccc1,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,,test
US20080027056A1,BrC(Br)(Br)Br.OCc1cncc(Br)c1>>BrCc1cncc(Br)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US06878721B1,COc1ccc(OC)c2c1CC(N)C2.O=c1ccc2c([C@@H]3CO3)ccc(OCc3ccccc3)c2[nH]1>>COc1ccc(OC)c2c1CC(NC[C@H](O)c1ccc(OCc3ccccc3)c3[nH]c(=O)ccc13)C2,,Cc1ccccc1,,,,test
US20150218170A1,Cc1nc2c(ccn2COCC[Si](C)(C)C)nc1Br.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>Cc1nc2c(nc1Br)c(C=O)cn2COCC[Si](C)(C)C,,ClCCl,,CN(C)C=O,,test
US20060264415A1,O=C(COCc1ccc(F)cc1)NCCCc1ccc(O[C@@H]2CCNC2)cc1.O=Cc1c[nH]c2ccccc12>>O=C(COCc1ccc(F)cc1)NCCCc1ccc(O[C@@H]2CCN(Cc3c[nH]c4ccccc34)C2)cc1,,C1CCOC1,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090028925A1,BrC(Br)(Br)Br.COCOc1ccc(Cc2c(C)cc(CO)cc2C)cc1Cc1ccc(F)cc1>>COCOc1ccc(Cc2c(C)cc(CBr)cc2C)cc1Cc1ccc(F)cc1,,CCOCC,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04657929,COc1ccc(CCNC(=O)C(F)(F)F)cc1N=Cc1ccccc1>>COc1ccc(CCNC(=O)C(F)(F)F)cc1NCc1ccccc1,O=[Pt],CCO,,,,test
US20070173488A1,CC(C)(C)OC(=O)Nc1ccc(C(=O)O)c(Cl)c1>>CNc1ccc(CO)c(Cl)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120135984A1,O=S(=O)(O)c1cccc2cnccc12.O=S(Cl)Cl>>O=S(=O)(Cl)c1cccc2cnccc12,,CN(C)C=O,,,,test
US20080096955A1,C1CCNC1.O=Cc1cc(F)cc(F)c1>>Fc1cc(F)cc(CN2CCCC2)c1,,C1CCOC1,CCOC(C)=O,O=C([O-])O.[Na+],,test
US20120283238A1,CCc1cc2c(N3CCC(NC(=O)OC(C)(C)C)CC3)ncnc2s1.Cl.ClCCl>>Cl.Cl.NC1CCNCC1,,ClCCl,,,,test
US04098791,CO.N#CN1CCCCC1>>COC(=N)N1CCCCC1,,CO,,C[O-].[Na+],,test
US20080262064A1,COc1nc(N)c(C(=O)OC(C)(C)C)n1-c1ccc(F)cc1.O=C(Cl)c1ccc(Cl)cc1Cl>>COc1nc(NC(=O)c2ccc(Cl)cc2Cl)c(C(=O)OC(C)(C)C)n1-c1ccc(F)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20050054629A1,BrCCCCCCBr.O=c1cc(COC2CCCCO2)occ1O>>CC(Br)CCCCOc1coc(COC2CCCCO2)cc1=O,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06218538B1,COc1ccc(C#N)cc1.[Cl-].[NH4+]>>COc1ccc(C(=N)N)cc1.Cl,,CO,,C[O-].[Na+],,test
US20110112065A1,CCCNCC.CS(=O)(=O)c1cc(F)c2c(c1)OC(CBr)OC2>>CCCN(CC)CC1OCc2c(F)cc(S(C)(=O)=O)cc2O1,,CCO,,,,test
US05538966,COC(=O)CN(c1ccc(OC)cc1)S(=O)(=O)c1sccc1C=O>>COC(=O)C1=Cc2ccsc2S(=O)(=O)N1c1ccc(OC)cc1,,CCOC(C)=O,,C1CCC2=NCCCN2CC1,,test
US05879894,Brc1cccc(C2OCCO2)c1.O=C1Nc2ccccc2C1=O>>O=C1C(=O)N(c2cccc(C3OCCO3)c2)c2ccccc21,,ClC(Cl)Cl,,[H][H],[H-].[Na+],test
US05360808,COC(=O)c1ccc(=O)n(CCNC(=O)c2cccnc2)c1.COS(=O)(=O)OC>>COC(=O)c1ccc(=O)n(CCN(C)C(=O)c2cccnc2)c1,,CN(C)C=O,,[H-].[Na+],,test
US20060111422A1,COC(=O)c1nn(-c2ccc(F)cc2)c(C=O)c1C(C)C>>CC(C)c1c(C(=O)O)nn(-c2ccc(F)cc2)c1C=O,,CO,,[Na+].[OH-],,test
US20090270443A1,Cc1c(Cl)nc(OS(=O)(=O)C(F)(F)F)c([N+](=O)[O-])c1NNC(=O)OC(C)(C)C.c1ccc(CNCc2ccccc2)cc1>>Cc1c(Cl)nc(N(Cc2ccccc2)Cc2ccccc2)c([N+](=O)[O-])c1NNC(=O)OC(C)(C)C,,Cc1ccccc1,,CCN(CC)CC,,test
US04453010,O=C(O)c1ccc(O)cc1.Oc1ccccc1>>O=C(c1ccc(O)cc1)c1ccc(O)cc1,,C1CCCCC1,,CS(=O)(=O)O,,test
US04550137,C=C(C)C(=O)OCCN(C)C.Cc1ccc(S(=O)(=O)O)cc1>>C=C(C)C(=O)OCCN(C)C.Cc1ccc(S(=O)(=O)O)cc1,,CO,,,,test
US20120283239A1,CS(=O)(=O)Cl.Cn1nnc2c(C#N)nc(-c3ccc(OCCO)c(C(F)(F)F)c3)cc21>>Cn1nnc2c(C#N)nc(-c3ccc(OCCOS(C)(=O)=O)c(C(F)(F)F)c3)cc21,,O,,CCN(C(C)C)C(C)C,CO,test
US20060004017A1,COCCOCCO.COc1cc2c(=O)n(COC(=O)C(C)(C)C)cnc2cc1O>>COCCOCCOc1cc2ncn(COC(=O)C(C)(C)C)c(=O)c2cc1OC,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05411980,CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(N)(=O)=O)cc1.O=C(O)c1ccccc1>>CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2)cc1,,C1CCOC1,,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US05194442,O=[N+]([O-])c1ccc2c(c1)[C@@H](O)[C@H](Br)CCO2>>O=[N+]([O-])c1ccc2c(c1)C1OC1CCO2,,CO,,[Na],,test
US20110263541A1,CN(C)/C=C/C(=O)c1cn(C)c2ccccc12.N=C(N)Nc1cccc(O)c1>>Cn1cc(-c2ccnc(Nc3cccc(O)c3)n2)c2ccccc21,,CC#N,,Cl,[Na+].[OH-],test
US20160002218A1,C1CCNC1.CC(=O)c1ccc(F)c(C(F)(F)F)c1>>CC(=O)c1ccc(N2CCCC2)c(C(F)(F)F)c1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20120330012A1,C[Si](C)(C)CCOCn1ccc2c1ncn1nnc(C3CCCCC3)c21>>c1cc2c(ncn3nnc(C4CCCCC4)c23)[nH]1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100216794A1,CCCI.Oc1ccc(Br)nc1>>CCCOc1ccc(Br)nc1,,CN(C)C=O,,O,[H-].[Na+],test
US20080281093A1,C/C=C/C1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccc(O)cc3)[C@H]2SC1.O>>C/C=C/C1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)c3ccc(O)cc3)[C@H]2SC1.O,,O,,CN(C)C=O,,test
US20120015969A1,COC(=O)c1cncc(-c2cccc(C(F)(F)F)c2)c1>>COC(=O)[C@@H]1CNC[C@H](c2cccc(C(F)(F)F)c2)C1,,CO,,,,test
US20130317065A1,COC(=O)c1cccc(CC(C(=O)c2ccsc2)c2ccc(OC)cc2NC(=O)OC(C)(C)C)n1>>COC(=O)c1cccc(Cc2c(-c3ccsc3)[nH]c3cc(OC)ccc23)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090197864A1,C[Mg]Br.O=Cc1cc(F)cc(Br)c1>>CC(O)c1cc(F)cc(Br)c1,,CCOCC,,C1CCOC1,,test
US20070185104A1,CN1CCNCC1.COC(=O)CCCNc1nccc(C(C#N)=C2Nc3ccccc3O2)n1>>CN1CCN(C(=O)CCCNc2nccc(C(C#N)=C3Nc4ccccc4O3)n2)CC1,,CO,,,,test
US04082751,C=O.CCCOc1ccc(N)cc1-c1ncc(-c2nnn[nH]2)c(=O)[nH]1.[BH3-]C#N>>CCCOc1ccc(N(C)C)cc1-c1ncc(-c2nnn[nH]2)c(=O)[nH]1,,CC#N,CC(=O)O,O,,test
US20150166480A1,CC(C)(F)CN1CCC(COc2ccc(-c3ccc(C(=O)O)cc3F)c(F)c2)CC1.OC[C@H]1CCCN1>>CC(C)(F)CN1CCC(COc2ccc(-c3ccc(C(=O)N4CCC[C@@H]4CO)cc3F)c(F)c2)CC1,,CN(C)C=O,,CCN(CC)CC,[Cl-].[NH4+],test
US20030171413A1,BrCCOc1ccccc1.O=C(Cc1cccc2cocc12)NC1CCNCC1>>O=C(Cc1cccc2cocc12)NC1CCN(CCOc2ccccc2)CC1,,CO,ClCCl,,,test
US20090042872A1,CN(CCOc1ccc(Br)cc1C=O)C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CNCCOc1ccc(Br)cc1C=O.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20140249139A1,CCOC(=O)c1cccc(-c2ncnc3ccc(-c4ccc(OC)nc4)cc23)c1>>COc1ccc(-c2ccc3ncnc(-c4cccc(C(=O)O)c4)c3c2)cn1,,C1COCCO1,,O,[Li]O,test
US20150210722A1,N#Cc1cc(OCCN2CCOCC2)cc([N+](=O)[O-])c1>>N#Cc1cc(N)cc(OCCN2CCOCC2)c1,[Fe],CCO,,O,[Cl-].[NH4+],test
US20120329785A1,CN1CCN(c2ncc(N)cn2)CC1.COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1>>COc1ccc2nc(Nc3cnc(N4CCN(C)CC4)nc3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US20080058386A1,COc1ccc(S(=O)(=O)N2CCc3cc(Br)cc(N)c32)cc1>>COc1ccc(S(=O)(=O)N2CCc3cccc(N)c32)cc1,,Cc1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,CCCC[SnH](CCCC)CCCC,test
US20070213331A1,CCCN(C)C(=O)c1cc(C=O)cc(C(=O)OCC)c1.C[Mg]Br>>CCCN(C)C(=O)c1cc(C(=O)OCC)cc(C(C)O)c1,,C1CCOC1,,,,test
US20160229960A1,CCO[Si](CCCC(O)(C(F)(F)F)C(F)(F)F)(OCC)OCC>>CCO[Si]1(OCC)CC=CC(C(F)(F)F)(C(F)(F)F)O1,,Cc1ccccc1,,,,test
US20090156600A1,CC(=O)OC(F)(F)Cl.CCc1[nH]c2c(F)ccc(OCC(=O)OC)c2c(=O)c1Cc1ccc(S(=O)(=O)CC)cc1.[NH4+]>>CCc1nc2c(F)ccc(OCC(=O)OC)c2c(OC(F)F)c1Cc1ccc(S(=O)(=O)CC)cc1.N,,[Cl-],[NH4+],CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130323268A1,CSS(C)(=O)=O.O=C(O)c1ccc(CS)cc1>>CSSCc1ccc(C(=O)O)cc1,,CCO,O,,,test
USH0001401,BrBr.C[Si](C)(C)c1ccccc1CO>>C[Si](C)(C)c1ccccc1CBr,,CC#N,CCOCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110003793A1,Cl.Cn1c2c(c3ccc(-n4ccc(-c5ccc(C(F)(F)F)nc5)cc4=O)nc31)CCN(C(=O)OC(C)(C)C)CC2>>Cl.Cn1c2c(c3ccc(-n4ccc(-c5ccc(C(F)(F)F)nc5)cc4=O)nc31)CCNCC2,,CCOCC,CO,,,test
US20150315198A1,CCOC(=O)C(=O)/C=C(\C)OCC.N#CCC(N)=O>>CCOC(=O)c1cc(C)c(C#N)c(=O)[nH]1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20060264460A1,CC(C)(C)OC(=O)COc1ccc(C=O)cc1Br.N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1>>CC(C)(C)OC(=O)COc1ccc(CNc2ccc3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)cc1Br,,CCO,,[BH3-]C#N.[Na+],,test
US20160257642A1,Nc1ccccc1N.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>Nc1ccccc1NC(=O)c1ccc([N+](=O)[O-])cc1,,ClCCl,,,,test
US05071871,CC1(C)Oc2ccc(C#N)cc2[C@@H](OC2=CC(=O)CC2)[C@@H]1O.O=C1COC(=O)C1>>CC1(C)Oc2ccc(C#N)cc2[C@@H](OC2=CC(=O)OC2)[C@@H]1O,,C1CCOC1,,[H-].[Na+],,test
US20070129356A1,Cc1ccc(N)cc1F.N#Cc1ccccc1Br>>Cc1ccc(NC(=N)c2ccccc2Br)cc1F,,ClC(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US04937246,CCOC(=O)CCCBr.COc1ccc(O)cc1OC>>COc1ccc(OCCCC(=O)O)cc1OC,,CN(C)C=O,,[I-].[K+],,test
US20040087577A1,COc1cccc(C=O)c1.Nn1c(=O)c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2sccc21>>COc1cccc(C=Nn2c(=O)c(C3=NS(=O)(=O)c4ccccc4N3)c(O)c3sccc32)c1,,CC(=O)N(C)C,,,,test
US03994937,CC(=O)OC(C)=O.CC[C@]12CC[C@@H]3[C@H]4CCC(=O)C=C4CC[C@H]3[C@@H]1[C@H]1C[C@H]1[C@@H]2O>>CC[C@]12CC[C@@H]3[C@H]4CCC(=O)C=C4CC[C@H]3[C@@H]1[C@H]1C[C@H]1[C@@H]2OC(C)=O,,c1ccncc1,,,,test
US20140155391A1,COC(=O)c1ccc(OCCN2CCOCC2)c(CN)c1.CS(=O)(=O)Cl>>COC(=O)c1ccc(OCCN2CCOCC2)c(CNS(C)(=O)=O)c1,,c1ccncc1,,,,test
US20140221361A1,C=C(CN(CCN(C)C)C(=O)OC(C)(C)C)[C@@H]1CC[C@]2(C(=O)NCCC(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC(C)(C)C)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(CNCCN(C)C)[C@@H]1CC[C@]2(C(=O)NCCC(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100267712A1,CCOC(=O)c1cc(OC)ccc1CBr.Nc1ccc2[nH]c(=O)[nH]c2c1>>COc1ccc2c(c1)C(=O)N(c1ccc3[nH]c(=O)[nH]c3c1)C2,,CCO,,CCN(C(C)C)C(C)C,,test
US07973063B2,CN(Cc1cccc(Br)c1)C(=O)OC(C)(C)C.O=Cc1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)NCc1cccc(-c2ccc(C=O)cc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20060052382A1,CC(C)(C)OC(=O)N[C@@H](CC(=O)O)Cc1cc(F)c(F)cc1F.CCN(C(C)C)C(C)C.CCOC(C)=O.CN(C)C=O.On1nnc2cccnc21>>COc1nnc2n1CCN(C(=O)C[C@@H](Cc1cc(F)c(F)cc1F)NC(=O)OC(C)(C)C)C2,,CCOC(C)=O,CN(C)C=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US04139617,C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43COC3CCCCO3)[C@@H]1CCC2=O>>C[C@]12CC[C@H]3[C@@H](CC=C4CC(=O)C=C[C@@]43COC3CCCCO3)[C@@H]1CCC2=O,,CS(C)=O,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US04948416,CCCCCI.O=S1(=O)NCc2cccc(Cl)c21>>CCCCCN1Cc2cccc(Cl)c2S1(=O)=O,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20030055265A1,CCOC(=O)C(OC)C(O)c1ccc(OCCCc2nc(-c3ccc(OC)cc3)oc2C)c2ccccc12>>CCOC(=O)C(Cc1ccc(OCCCc2nc(-c3ccc(OC)cc3)oc2C)c2ccccc12)OC,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20150274696A1,CCOC(=O)c1cnc(Cl)cc1Cl>>O=C(O)c1cnc(Cl)cc1Cl,,CCO,O,[Li+].[OH-],,test
US05409809,Fc1c(F)c(F)c(CBr)c(F)c1F.Sc1nc2ccccc2[nH]1>>Fc1c(F)c(F)c(CSc2nc3ccccc3[nH]2)c(F)c1F,,CCO,,O,[Na+].[OH-],test
US20160106102A1,FC(F)(F)c1cnc(CCl)c(Cl)c1.O=[N+]([O-])c1cc[nH]n1>>O=[N+]([O-])c1ccn(Cc2ncc(C(F)(F)F)cc2Cl)n1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20120034270A1,II.c1ccc2c(c1)CCCN2>>Ic1ccc2c(c1)CCCN2,,O,,OO,,test
US06060484,CCc1ccccc1N.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCc1ccccc1N=C=O,,ClCCl,,CCN(CC)CC,,test
US20120041004A1,Cc1c[nH]c2c(=O)n(C)c(=O)n(C)c12.O=C(CBr)Nc1nc(-c2ccc(F)cc2F)cs1>>Cn1c(=O)c2c(ccn2CC(=O)Nc2nc(-c3ccc(F)cc3F)cs2)n(C)c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20020177721A1,O=C(OCc1ccccc1)N1CCC[C@@H](CO)C1>>O=CC1CCCN(C(=O)OCc2ccccc2)C1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20130065907A1,NCc1nc(C(F)(F)F)no1.O=C(O)c1cnc(OCC(F)(F)F)c(C2CCCC2)c1>>O=C(NCc1nc(C(F)(F)F)no1)c1cnc(OCC(F)(F)F)c(C2CCCC2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05034417,CS(=O)(=O)Cl.N#Cc1ccc(N)c(Nc2ccc(F)cc2F)c1>>CS(=O)(=O)Nc1ccc(C#N)cc1Nc1ccc(F)cc1F,,c1ccncc1,,,,test
US20130040930A1,CC(=O)Cl.CC(C)(CO)CBr>>CC(=O)OCC(C)(C)CBr,,O,,C1CCOC1,CCN(CC)CC,test
US20120295887A1,Cc1c(C=O)[nH]c2c1C(=O)N(C[C@H](O)CN1CCOCC1)CCC2.O=C1Cc2cc(F)ccc2N1>>Cc1c(/C=C2\C(=O)Nc3ccc(F)cc32)[nH]c2c1C(=O)N(C[C@H](O)CN1CCOCC1)CCC2,,CCO,,C1CCNCC1,,test
US20100286112A1,COC(=O)C(Cc1ccc(OCC[C@@H](C)C2CCN(c3nc(C(C)C)no3)CC2)cc1)NC(=O)OC(C)(C)C>>CC(C)c1noc(N2CCC([C@H](C)CCOc3ccc(CC(NC(=O)OC(C)(C)C)C(=O)O)cc3)CC2)n1,,C1CCOC1,O,[Li]O,,test
US06136821,C[Si](C)(C)C#Cc1cc2cccnc2c(-c2cccc([N+](=O)[O-])c2)n1>>C#Cc1cc2cccnc2c(-c2cccc([N+](=O)[O-])c2)n1,,CO,Cc1ccccc1,[K+].[OH-],,test
US03943141,CCOc1ccc2c(=O)c(C(=O)O)c[nH]c2n1.Nc1nnn[nH]1>>CCOc1ccc2c(=O)c(C(=O)Nc3nnn[nH]3)c[nH]c2n1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20130059834A1,COC[C@@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(C)c4cc(Cl)ccc34)nc12)C(=O)N1CC(F)C1>>COC[C@@H](NC(=O)c1c[nH]c2ncc(-c3nn(C)c4cc(Cl)ccc34)nc12)C(=O)N1CC(F)C1,,ClCCl,,NCCN,O=C(O)C(F)(F)F,test
US20090281088A1,C=CCC(O)(Cn1cc([N+](=O)[O-])nc1Cl)c1ccc(Br)cc1>>C=CCC1(c2ccc(Br)cc2)Cn2cc([N+](=O)[O-])nc2O1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OC(CCOS(=O)(=O)c3ccc(C)cc3)C(=O)OCC)CC2)c2ncnn12>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OC3(C(=O)OCC)CC3)CC2)c2ncnn12,,C1CCOC1,,Cl,CC(C)(C)[O-].[K+],test
US20140031552A1,COc1ccc2c(c1[N+](=O)[O-])C(=O)N(C1CCC(=O)NC1=O)C2=O>>COc1ccc2c(c1N)C(=O)N(C1CCC(=O)NC1=O)C2=O,[Pd],CN(C)C=O,,[H][H],,test
US20120108619A1,N#Cc1cc(C(=O)O)ccc1F.NN>>Nc1n[nH]c2ccc(C(=O)O)cc12,,CCO,,O,,test
US20150274734A1,CN(C)C=O.c1ccc(CN2CCn3cncc3C2)cc1>>O=Cc1ncc2n1CCN(Cc1ccccc1)C2,,C1CCOC1,,[Li]CCCC,,test
US20160096827A1,C[C@H](O)C(=O)N1CC[C@H](Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C#N)[C@H](F)C1.FC(F)Oc1cc(Nc2ncnc(Cl)n2)ccc1N1CCN(C2COC2)CC1>>C[C@H](O)C(=O)N1CC[C@H](Oc2ccc(-c3ncnc(Nc4ccc(N5CCN(C6COC6)CC5)c(OC(F)F)c4)n3)cc2C#N)[C@H](F)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20140329929A1,C=C(C)C(=O)OCc1ccco1.CCO[Si](CCCN1C(=O)C=CC1=O)(OCC)OCC>>C=C(C)C(=O)OCC12C=CC(O1)C1C(=O)N(CCC[Si](OCC)(OCC)OCC)C(=O)C12,,Cc1ccccc1,,,,test
US20060142265A1,C=CC(=O)Cl.CCCOc1c(Cl)cccc1CCN>>C=CC(=O)N(C)Cc1cccc(Cl)c1OCCC,,ClCCl,,CCN(CC)CC,,test
US20060079505A1,COS(=O)(=O)OC.O=C1Cc2ccccc2N1>>CN1C(=O)Cc2ccccc21,,Cc1ccccc1C,,[H-].[Na+],,test
US20040023964A1,COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1F.FC(F)(F)c1cnn2c(Br)cnc2n1>>COc1cc(-c2cnc3nc(C(F)(F)F)cnn23)ccc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,COCCOC,O=C([O-])O.[Na+],,test
US05866564,C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(S[C@H]3C[C@@H](C(=O)N4CC[C@H](n5cncn5)C4)N(C(=O)OCc4ccc([N+](=O)[O-])cc4)C3)[C@H](C)[C@H]12.Cl>>C[C@@H](O)[C@H]1C(=O)N2C(C(=O)O)=C(S[C@@H]3CN[C@H](C(=O)N4CC[C@H](n5cncn5)C4)C3)[C@H](C)[C@H]12.Cl,,C1CCOC1,O,,,test
US20050070479A1,NC(C(=O)C(F)(F)F)C1CCN(C(=O)OCc2ccccc2)CC1>>NCC1CCN(C(=O)OCc2ccccc2)CC1,,C1COCCO1,,[Na+].[OH-],,test
US20120108583A1,COC(=O)c1cc2nc(Nc3c(F)cccc3Cl)[nH]c2c2nc(C)oc12.Nc1ccc(F)c(C(F)(F)F)c1>>Cc1nc2c(o1)c(C(=O)Nc1ccc(F)c(C(F)(F)F)c1)cc1nc(Nc3c(F)cccc3Cl)[nH]c12,,Cc1ccccc1,,C[Al](C)C,,test
US20090270350A1,COC(=O)c1ccc(C)c(-n2c(SC)nc(O)cc2=O)c1.O=C1c2ccccc2C(=O)N1Cc1ccccc1CCl>>COC(=O)c1ccc(C)c(-n2c(SC)nc(OCc3ccccc3CN3C(=O)c4ccccc4C3=O)cc2=O)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060135516A1,O=C(Nc1ccc(F)cc1)c1n[nH]c2ccc([N+](=O)[O-])cc12>>Nc1ccc2[nH]nc(C(=O)Nc3ccc(F)cc3)c2c1,[Pd],CN(C)C=O,,CCO,,test
US20020032207A1,CCOC(=O)C1CCC(Cc2nc3ccccc3[nH]2)CC1>>O=C(O)[C@@H]1CC[C@H](Cc2nc3ccccc3[nH]2)CC1,,C1CCOC1,,[Li+].[OH-],,test
US20010051631A1,Cc1cn2c(CO)cccc2n1.O=S(Cl)Cl>>Cc1cn2c(CCl)cccc2n1.Cl,,Cc1ccccc1,,ClCCl,,test
US20040176365A1,CC(=O)OC(C)=O.O=c1c(CCC(O)c2ccncc2)cc2cccnc2n1-c1cccc([N+](=O)[O-])c1>>CC(=O)OC(CCc1cc2cccnc2n(-c2cccc([N+](=O)[O-])c2)c1=O)c1ccncc1,,c1ccncc1,,,,test
US20050054633A1,COc1ccc(CCl)cc1.O=C1Cc2ccccc2-c2ccccc2N1>>COc1ccc(CN2C(=O)Cc3ccccc3-c3ccccc32)cc1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US06514964B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCCCNCc1cc(F)ccc1Br>>CC(C)(C)OC(=O)N(CCCO)Cc1cc(F)ccc1Br,,ClCCl,,,,test
US20100144760A1,C=C[Sn](CCCC)(CCCC)CCCC.COC(=O)c1ccc(C)nc1Br>>C=Cc1nc(C)ccc1C(=O)OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20070265278A1,NC1CCCCC1.O=C(O)CCC(=O)c1ccc(Cl)c(S(=O)(=O)Cl)c1>>O=C(O)CCC(=O)c1ccc(Cl)c(S(=O)(=O)NC2CCCCC2)c1,,ClCCl,,CO,Cl,test
US05100897,CCCCC(=N)NCc1ccc(-c2ccccc2C#N)cc1.CCOC=C(C(=O)OCC)C(=O)OCC>>CCCCc1ncc(C(=O)OCC)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1,,CN(C)C=O,,CO,,test
US20140128371A1,C[C@H]1CN(c2c(C=O)nc3c(-c4ccc(C#N)c(F)c4)noc3c2Cl)C[C@@H](C)O1.O=C1CC(=O)NC(=O)N1>>C[C@@H]1CN2c3c(nc4c(-c5ccc(C#N)c(F)c5)noc4c3Cl)CC3(C(=O)NC(=O)NC3=O)[C@H]2[C@H](C)O1,,CC(C)O,,,,test
US06130187,COc1cc(Cl)cc(F)c1-n1c(=O)cc(C(F)(F)F)n(C)c1=O>>Cn1c(C(F)(F)F)cc(=O)n(-c2c(O)cc(Cl)cc2F)c1=O,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20150329538A1,Cc1cc2cccc(Br)c2nc1Cl.Nc1ccccc1>>Cc1cc2cccc(Br)c2nc1Nc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20090221555A1,COc1ccc([N+](=O)[O-])c2c1CCCC(N1CCOCC1)C2>>COc1ccc(N)c2c1CCCC(N1CCOCC1)C2,[Pd],CCO,,,,test
US04610984,COc1ccc(C(=O)Cl)cc1.ClCCl.O=C(CN1CCNCC1)N1CCCC1>>COc1ccc(C(=O)N2CCN(CC(=O)N3CCCC3)CC2)cc1.Cl,,ClCCl,,,,test
US06458784B1,COC(=O)CC1Cc2ccc(C(=O)O)cc2CN(C)C1=O.OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COC(=O)CC1Cc2ccc(NC(=O)OCc3ccccc3)cc2CN(C)C1=O,,Cc1ccccc1,,CCN(CC)CC,,test
US20100311790A1,C#CCBr.O=C(NCc1cccc(O)c1)c1ccc2ncccc2c1>>C#CCOc1cccc(CNC(=O)c2ccc3ncccc3c2)c1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US05274118,C[C@@H](CO)CC(F)(F)F.O=C1NC(=O)c2ccccc21>>C[C@@H](CN1C(=O)c2ccccc2C1=O)CC(F)(F)F,,C1CCOC1,CCOCC,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140155391A1,COc1ccc(C(=O)O)cc1N.O=C(Cl)CBr>>COc1ccc(C(=O)O)cc1NC(=O)CBr,CN(C)c1ccncc1,ClCCl,,,,test
US20070099944A1,CC(=O)CC(=O)Nc1cc2cn[nH]c2cc1Cl.NC(N)=O.O=Cc1ccc(F)cc1>>CC1=C(C(=O)Nc2cc3cn[nH]c3cc2Cl)C(c2ccc(F)cc2)NC(=O)N1,,O,,O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3],,test
US06365736B1,CC1Oc2ccc(CO)cc2NC1=O.CS(=O)(=O)Cl>>CC1Oc2ccc(CCl)cc2NC1=O,,ClCCl,,CCN(CC)CC,,test
US20050203078A1,Cn1ccc(C(NC(=O)OC(C)(C)C)c2nc3cc(Cl)ccc3[nH]2)n1>>Cn1ccc(C(N)c2nc3cc(Cl)ccc3[nH]2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04623650,CCOC(=O)c1cn2c3c(c(-c4ccc(S(=O)(=O)Cl)cc4)c(F)cc3c1=O)OCC2C.N>>CCOC(=O)c1cn2c3c(c(-c4ccc(S(N)(=O)=O)cc4)c(F)cc3c1=O)OCC2C,,C1CCOC1,,,,test
US04780537,Nc1cc(Cl)nc(N)n1.OO>>N=c1nc(Cl)cc(N)n1O,,C1CCOC1,,CC(=O)O,,test
US20050032786A1,NCCc1cccc(-c2nc(=O)c3ccccc3s2)n1.O=C=Nc1ccccc1>>O=C(NCCc1cccc(-c2nc(=O)c3ccccc3s2)n1)Nc1ccccc1,,CC#N,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20080004245A1,O=C(O)Cc1ccccc1Nc1c(Cl)cccc1Cl.Oc1ccc(-c2cc(=S)ss2)cc1.Oc1cccc2[nH]nnc12>>O=C(Cc1ccccc1Nc1c(Cl)cccc1Cl)Oc1ccc(N=C=S)cc1,,CCOC(C)=O,CN(C)C=O,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20060094735A1,CC(C)(C)OC(=O)CBr.Cc1ccc(-c2nc(CCN)cn2C(c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1>>Cc1ccc(-c2nc(CCNCC(=O)OC(C)(C)C)cn2C(c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20120040985A1,CC(C)(c1ccc(Cl)c(Cl)c1)c1c[nH]c(=S)n1-c1ccc(F)cc1.N#Cc1cc(CBr)ccc1F>>CC(C)(c1ccc(Cl)c(Cl)c1)c1cnc(SCc2ccc(F)c(C#N)c2)n1-c1ccc(F)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04032525,CSc1ccc2c(c1)C(Cl)Cc1cc(C)ccc1O2.O=C1CCCCN1CCN1CCNCC1>>CSc1ccc2c(c1)C(N1CCN(CCN3CCCCC3=O)CC1)Cc1cc(C)ccc1O2,,ClC(Cl)Cl,,,,test
US20040054178A1,C1COCCN1.CC#N.CCOC(=CC=CC=C[C+](OCC)c1ccc(C)cc1)c1ccc(C)cc1.F[B-](F)(F)F>>Cc1ccc(C(=CC=CC=C[C+](c2ccc(C)cc2)N2CCOCC2)N2CCOCC2)cc1.F[B-](F)(F)F,,CC#N,,,,test
US20140315917A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(Oc2ccnc(Cl)c2)cn1>>CC(C)(C)OC(=O)Nc1ccc(Oc2ccnc(Cl)c2)cn1,CN(C)c1ccncc1,C1CCOC1,CCOC(C)=O,,,test
US05451677,NCCc1ccc(N)cc1.O=C(Cl)OCc1ccccc1>>Nc1ccc(CCNC(=O)OCc2ccccc2)cc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20100004238A1,COC(=O)c1cnn2cc(OCc3ccccc3)ccc12>>COC(=O)c1cnn2cc(O)ccc12,[Pd],CO,,,,test
US08420830B2,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCc1cc([N+](=O)[O-])ccc1Br>>CN(Cc1cc([N+](=O)[O-])ccc1Br)C(=O)OC(C)(C)C,,C1CCOC1,,c1c[nH]cn1,,test
US20080026317A1,COC(=O)/C=C/CC(O)(C(F)(F)F)C(F)(F)F>>COC(=O)CCCC(O)(C(F)(F)F)C(F)(F)F,[Pd],CCOC(C)=O,,,,test
US20110065707A1,CC(Oc1ccc([N+](=O)[O-])cn1)C(F)(F)F>>CC(Oc1ccc(N)cn1)C(F)(F)F,[Pd],CO,,,,test
US20070149542A1,COC(=O)N1CCC(c2cccc(S(C)(=O)=O)c2F)CC1>>CS(=O)(=O)c1cccc(C2CCNCC2)c1F,,CCO,Cl,,,test
US20150203499A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)COc1ncnc2[nH]cc(I)c12>>CC(C)COc1ncnc2c1c(I)cn2C(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,,,test
US20110152258A1,CCc1ccc(S(=O)(=O)Cl)cc1.COc1ncnc2[nH]cc(C(=O)c3c(F)ccc(N)c3F)c12>>CCc1ccc(S(=O)(=O)Nc2ccc(F)c(C(=O)c3c[nH]c4ncnc(OC)c34)c2F)cc1,,C1CCOC1,,c1ccncc1,,test
US20100160297A1,COc1ccc(S(=O)(=O)N2CCCNCC2)c2ccnc(C)c12.Cl>>COc1ccc(S(=O)(=O)N2CCCNCC2)c2ccnc(C)c12.Cl,,CCOCC,,,,test
US05142056,Br[Mg]CCc1ccccc1.CCOCC.CCOP([O-])OCC>>O=[PH](CCc1ccccc1)CCc1ccccc1,,CCOCC,,[Cl-].[NH4+],,test
US20100240658A1,COC(=O)c1ccc(-c2c(C)noc2C)c(C)c1>>Cc1cc(C(=O)O)ccc1-c1c(C)noc1C,,CCO,O,[Na+].[OH-],,test
US20060111375A1,CCOCC.Cc1ccoc1C.N#Cc1cccnc1>>Cc1cc(C(=O)c2cccnc2)oc1C,,CCCCCC,,Cl,[Li]CCCC,test
US20100267634A1,COC(=O)c1ccc(/C=C/[C@@H]2CCCN2C(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)N1CCC[C@H]1/C=C/c1ccc(CO)cc1,,ClCCl,,CC(C)C[Al+]CC(C)C.[H-],,test
US20090029975A1,CCOC(=O)CCc1cc(Cl)ccn1.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)CCc1cc(Cl)cc[n+]1[O-],,CCOC(C)=O,,,,test
US20080275240A1,CC[Si](Cl)(CC)CC.CN1C[C@H](CO)C=C2c3cccc4c3C(CN4)C[C@H]21>>CC[Si](CC)(CC)OC[C@@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1,CN(C)c1ccncc1,CN(C)C=O,,CCN(CC)CC,O,test
US04940710,C=O.CCCCCCOCC1CN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3CC)CCN1>>CCCCCCOCC1CN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3CC)CCN1C,,O=CO,,,,test
US04965398,C=C(C)C.CC(C)OC(=O)C=O>>C=C(C)C[C@@H](O)C(=O)OC(C)C,,O=C([O-])O,[Na+],,,test
US20090233903A1,CCS(=O)(=O)N1CC(=CC#N)C1.C[Si](C)(C)CCOCn1ccc2c(-c3cc[nH]c3)ncnc21>>CCS(=O)(=O)N1CC(CC#N)(n2ccc(-c3ncnc4[nH]ccc34)c2)C1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20090275628A1,CC(C)(C)c1ccc(C=NO)cc1.O=C1CCC(=O)N1Cl>>CC(C)(C)C1=CCC(Cl)(C=NO)C=C1,,CN(C)C=O,,O,,test
US20150175562A1,BrC(Br)(Br)Br.CC(C)(C)c1cc(-c2ncsc2CC2CCCCC2)cc(C(C)(C)C)c1>>CC(C)(C)c1cc(-c2nc(Br)sc2CC2CCCCC2)cc(C(C)(C)C)c1,,C1CCOC1,,[Li]CCCC,,test
US20130029987A1,CSc1ncc(C(=O)O)c(N[C@@H]2CCC[C@H](O)C2)n1.[NH4+]>>CSc1ncc(C(N)=O)c(N[C@@H]2CCC[C@H](O)C2)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030176418A1,CCCC=C1CCNCC1.C[C@H](CI)CN1C(=O)COc2cc(F)ccc21>>CCCC=C1CCN(C[C@@H](C)CN2C(=O)COc3cc(F)ccc32)CC1,,CCCCCCC,CCOC(C)=O,,,test
US20060030559A1,CN(C)C=O.Cc1nc(C#Cc2ccnc(Cl)c2)cn1-c1ccc(F)cc1>>Cc1nc(C#Cc2ccnc(Cl)c2)c(C=O)n1-c1ccc(F)cc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20090118336A1,CC(=O)Nc1cc(-c2cncc(N)c2)n(C)n1.Cc1nn(C)c(Cl)c1S(=O)(=O)Cl>>CC(=O)Nc1cc(-c2cncc(NS(=O)(=O)c3c(C)nn(C)c3Cl)c2)n(C)n1,,c1ccncc1,,C1CCNC1,,test
US05786356,O=c1[nH]c2cccc(OCC(O)CN(Cc3ccccc3)Cc3ccccc3)c2[nH]1>>NC[C@H](O)COc1cccc2[nH]c(=O)[nH]c12,[Pd],CO,,O=C[O-].[NH4+],,test
US20060135554A1,CCN(CC)C(=O)c1ccc(NCCNC(=O)OC(C)(C)C)c([N+](=O)[O-])c1>>CCN(CC)C(=O)c1ccc(NCCNC(=O)OC(C)(C)C)c(N)c1,[Pd],CCOC(C)=O,,,,test
US20050176701A1,Br[Mg]C1CCCC1.O=C(CCc1ccc(OCc2ccccc2)cc1)Sc1ccccn1>>O=C(CCc1ccc(OCc2ccccc2)cc1)C1CCCC1,,C1CCOC1,,CCOCC,,test
US20090197871A1,CC(C)(C)OC(=O)N1CCNCC1.CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2cccc(-c3cccc(C=O)c3)c2C)c1.ClCCCl>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2cccc(-c3cccc(CN4C[C@@H]5C[C@H]4CN5)c3)c2C)c1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20110015212A1,Cc1csc2nc(C(C)N=[N+]=[N-])c(Br)c(=O)n12.OB(O)c1ccc(F)cc1>>Cc1csc2nc(C(C)N=[N+]=[N-])c(-c3ccc(F)cc3)c(=O)n12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,O,O=C([O-])[O-].[Na+].[Na+],test
US20100160388A1,COc1cc(Br)c(N=C=O)cc1OC.O=C1C=CN[C@H](c2ccc(F)cc2)C1>>COc1cc(Br)c(NC(=O)N2C=CC(=O)C[C@H]2c2ccc(F)cc2)cc1OC,,C1CCOC1,,[Li]CCCC,,test
US20020193396A1,CNCCOCCn1c(CCOC)nc2c(N)nc3ccccc3c21>>CNCCOCCn1c(CCOC)nc2c(N)nc3c(c21)CCCC3,O=[Pt]=O,O,O=C(O)C(F)(F)F,,,test
US05256675,Nc1ncc(Sc2ccncc2)s1.O=C(Cl)c1ccc(F)cc1>>O=C(Nc1ncc(Sc2ccncc2)s1)c1ccc(F)cc1,,CN(C)C=O,,c1ccncc1,,test
US20040063754A1,CCOC(=O)c1cn([C@@H]2C[C@@H]2F)c2c(Cl)c(Cl)ccc2c1=O>>O=C(O)c1cn([C@@H]2C[C@@H]2F)c2c(Cl)c(Cl)ccc2c1=O,,O,,CC(=O)O,Cl,test
US20150203515A1,CCOC(=O)C12CCC(N)(CC1)CC2=O>>CCOC(=O)C12CCC(N)(CC1)CC2O,,CCO,,[BH4-].[Na+],,test
US20110039843A1,Fc1cnccc1-c1nc2cc(C(F)(F)F)ccc2o1.Oc1ccccc1>>FC(F)(F)c1ccc2oc(-c3ccncc3Oc3ccccc3)nc2c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20160175289A1,C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(NC3CN(C(=O)OC(C)(C)C)C3)cc2F)N1CC(F)(F)CO>>C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(NC3CNC3)cc2F)N1CC(F)(F)CO,,C1COCCO1,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US05843983,CC(C)(C)OC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]1CCCl.Oc1ccc(F)cc1CCc1ccc(F)cc1>>CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1CCOc1ccc(F)cc1CCc1ccc(F)cc1,,CC(=O)N(C)C,,CCOC(C)=O,CC(C)(C)[O-].[K+],test
US20060063738A1,CCCCCCCC/C=C\CCCCCCCCOCC(O)CO.CI.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCCCCC/C=C\CCCCCCCCOCC(COC(c1ccccc1)(c1ccccc1)c1ccccc1)OC,,O,c1ccncc1,[H-].[Na+],,test
US20120208797A1,CC(C)(C)[Si](C)(C)OCC(=O)c1ccccc1.OCCO>>CC(C)(C)[Si](C)(C)OCC1(c2ccccc2)OCCO1,Cc1ccc(S(=O)(=O)O)cc1,c1ccccc1,,,,test
US05888531,COc1ccc(C[C@H](NC(=O)OCc2ccccc2)C(=O)N2CCN(CC(=O)O)C(=O)[C@@H]2CCCN)cc1.Cl.N=C(N)Nc1ccc(C(=O)ON2C(=O)C3C4C=CC(C4)C3C2=O)cc1>>COc1ccc(C[C@H](NC(=O)OCc2ccccc2)C(=O)N2CCN(CC(=O)O)C(=O)[C@@H]2CCCNC(=O)c2ccc(NC(=N)N)cc2)cc1.Cl,,C1COCCO1,,Cl,O=C([O-])O.[Na+],test
US04647398,CCCCCCCC(=O)Cl.O=Cc1ccc(O)cc1>>CCCCCCCC(=O)Oc1ccc(C=O)cc1,,c1ccncc1,,Cc1ccccc1,Cl,test
US20070105943A1,CS(=O)(=O)Cl.OCc1cccc(OCc2ccccc2)c1>>ClCc1cccc(OCc2ccccc2)c1,,ClCCl,,CCN(CC)CC,,test
US20040014802A1,CCCC(=O)Nc1nn(COCC[Si](C)(C)C)c2cc(-c3ccc(OCc4ccccc4)cc3)c(-c3ccc(OCc4ccccc4)cc3)cc12>>CCCC(=O)Nc1n[nH]c2cc(-c3ccc(OCc4ccccc4)cc3)c(-c3ccc(OCc4ccccc4)cc3)cc12,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20020133023A1,COC(=O)CCCC=O.Nc1ccccn1>>COC(=O)CCCCNc1ccccn1,,ClCCl,,O=C([O-])O.[Na+],,test
US20060025423A1,COc1nc(Cl)cnc1N(COCCO[Si](C)(C)C)S(=O)(=O)c1cccc(Cl)c1Cl.NC(=O)CO>>COc1nc(NC(=O)CO)cnc1NS(=O)(=O)c1cccc(Cl)c1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20030166639A1,CC(C)(C)OC(=O)Nc1ccc(C(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-c2cccnn2)c1>>O=C1CC(c2cccc(-c3cccnn3)c2)=Nc2ccc(C(F)(F)F)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150005289A1,Brc1cnc(Br)cn1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(c2cnc(Br)cn2)CC1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20120322785A1,N#Cc1c(N)ncc2cc(Br)ccc12>>Nc1cc2ccc(Br)cc2cn1,,O,,O=S(=O)(O)O,[Na+].[OH-],test
US04046901,OC1(c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)CCCN(Cc2ccccc2)C1>>C1=C(c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)CN(Cc2ccccc2)CC1,,Cl,ClCCl,[Na+].[OH-],,test
US20020037910A1,CC(C)c1cccc(C(C)C)c1N.O=C(O)CCCCCCCBr>>CC(C)c1cccc(C(C)C)c1NC(=O)CCCCCCCBr,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20130150339A1,COc1cc(I)ccc1Br.O=C1COC1>>COc1cc(C2(O)COC2)ccc1Br,,CCOCC,,[Li]CCCC,,test
US04771046,CC(C)(C)OC(=O)N1CCC(=O)C1.NO>>CC(C)(C)OC(=O)N1CCC(=NO)C1,,CCO,,Cl,c1ccncc1,test
US20150232483A1,COc1ccc(CN2OCC3CNCC32c2cccnc2)cc1.Fc1cnc(Cl)nc1>>COc1ccc(CN2OCC3CN(c4ncc(F)cn4)CC32c2cccnc2)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US05580883,CC(=O)N1CCC(O)CC1.Cc1cc([N+](=O)[O-])ccc1F>>CC(=O)N1CCC(Oc2ccc([N+](=O)[O-])cc2C)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US20100105723A1,Cl.O=c1[nH]c2cc(-c3c(F)cncc3F)c(-c3ccccc3F)nc2[nH]1>>Cl.O=c1[nH]c2cc(-c3c(F)cncc3F)c(-c3ccccc3F)nc2[nH]1,,C1COCCO1,CCOCC,,,test
US20050272779A1,CC(O)C(N)=NO.O=C(Cl)c1cccc(Cl)c1>>CC(O)C(N)=NOC(=O)c1cccc(Cl)c1,,C1CCOC1,,CCOCC,,test
US20050070562A1,Cc1c(Oc2ccc(S(C)(=O)=O)cc2F)ncnc1OC1CCNCC1.Cc1ccc(S(=O)(=O)OCCc2cccnc2)cc1>>Cc1c(Oc2ccc(S(C)(=O)=O)cc2F)ncnc1OC1CCN(CCc2cccnc2)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US05552379,CC(C)(C)c1ccc2c(c1)C(CCO)CC2>>CC(C)(C)c1ccc2c(c1)C(CC=O)CC2,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US04006145,CN1CCN(CCCl)C1=O.Clc1ccc2c(c1)CC(N1CCNCC1)c1ccccc1S2>>CN1CCN(CCN2CCN(C3Cc4cc(Cl)ccc4Sc4ccccc43)CC2)C1=O,,Cc1ccccc1,O,[I-].[K+],,test
US20110098296A1,Cc1nc(-c2cccc(NC(=O)c3c(F)cccc3F)c2)c(-c2ccnc(Cl)n2)s1.Nc1cccc(CN2CCCC2)c1>>Cc1nc(-c2cccc(NC(=O)c3c(F)cccc3F)c2)c(-c2ccnc(Nc3cccc(CN4CCCC4)c3)n2)s1,Cl,CC(C)O,,,,test
US20160002188A1,O=C(O)c1ncc(Br)cn1.O=S(Cl)Cl>>O=C(Cl)c1ncc(Br)cn1,,CN(C)C=O,,,,test
US20140206618A1,COC(=O)C1CCc2nc(N)ncc21>>Nc1ncc2c(n1)CCC2C(=O)O,,CO,,Cl,[Na+].[OH-],test
US20110172237A1,O=C(CCl)Nc1ncns1.O=C(O[C@H]1CN2CCC1CC2)C1(c2ccccc2)CCCCCC1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C1(c3ccccc3)CCCCCC1)C2)Nc1ncns1.[Cl-],,CC#N,,,,test
US05225402,O=C(O)c1c(F)cccc1NC1CCN(Cc2ccccc2)CC1>>OCc1c(F)cccc1NC1CCN(Cc2ccccc2)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05185346,CC(C)C(c1ccc([N+](=O)[O-])cc1)n1ccnc1>>CC(C)C(c1ccc(N)cc1)n1ccnc1,[Ni],CO,,,,test
US06022906,CN(C)C(C)(Cc1ccccc1)C(=O)c1ccc(F)cc1.SCCCS>>CN(C)C(C)(Cc1ccccc1)C(=O)c1cccc(SCCCS)c1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20070105872A1,COB1OC(C)(C)C(C)(C)O1.COc1c(Cl)cc(Cl)cc1Br>>COc1c(Cl)cc(Cl)cc1B1OC(C)(C)C(C)(C)O1,,CCOCC,,[Li]C(C)(C)C,,test
US20110195954A1,COCCC1(C)C(=O)Nc2ccc(F)cc21>>COCCC1(C)CNc2ccc(F)cc21,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20070149561A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=[N+]([O-])c1ccc(-c2nn(CCO)cc2Br)cc1>>CC1(C)OB(c2cn(CCO)nc2-c2ccc([N+](=O)[O-])cc2)OC1(C)C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,CC(=O)[O-].[K+],,test
US20070179165A1,ClCCl.O=C(O)c1c(Cl)cccc1[N+](=O)[O-]>>COC(=O)c1c(Cl)cccc1[N+](=O)[O-],CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US04863942,CCCc1c(OCCCOc2cc(N)c(C)cc2Br)ccc(C(C)=O)c1O.COC(=O)C(=O)Cl>>CCCc1c(OCCCOc2cc(NC(=O)C(=O)OC)c(C)cc2Br)ccc(C(C)=O)c1O,,ClCCl,,CCN(CC)CC,,test
US20140107094A1,CON(C)C(=O)c1cnnn1C.COc1nc2ccc(I)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1>>COc1nc2ccc(C(=O)c3cnnn3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1,,C1CCOC1,,CC(C)[Mg]Cl,[Cl-].[NH4+],test
US20100174065A1,CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CNCCO4)no2)cc1C#N.CCOC(=O)CCCBr>>CCOC(=O)CCCN1CCOc2ccc(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cc2C1,,CC#N,CCOC(C)=O,CCN(C(C)C)C(C)C,Cl,test
US20040176308A1,CC(C)c1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccccc1OCc1cccc(CO[Si](C)(C)C(C)(C)C)c1>>CC(C)c1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccccc1OCc1cccc(CO)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140288045A1,C=Cc1cc(Cl)c(Br)cc1N.OB(O)c1ccccc1Cl>>C=Cc1cc(Cl)c(-c2ccccc2Cl)cc1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20050096336A1,CC[Mg]Cl.Cc1nc(-c2cccc(C(F)(F)F)c2)ccc1C=O>>CCC(O)c1ccc(-c2cccc(C(F)(F)F)c2)nc1C,,C1CCOC1,,,,test
US20110021569A1,CC(C)(C)OC(=O)N1CCCC(O)C1.O=C=Nc1ccc(Br)cc1>>CC(C)(C)OC(=O)N1CCCC(OC(=O)Nc2ccc(Br)cc2)C1,,Cc1ccccc1,,,,test
US04538006,CC(C)(C)c1cccc(C(C)(C)C)c1O.O=[N+]([O-])c1cccc([N+](=O)[O-])c1>>CC(C)(C)c1cc(-c2ccc([N+](=O)[O-])cc2[N+](=O)[O-])cc(C(C)(C)C)c1O,,CS(C)=O,,Cl,[Na+].[OH-],test
US20130331419A1,COC(=O)C(c1ccc(Cl)cc1)n1ccc2c(NC(=O)OC(C)(C)C)cccc21.CS(=O)(=O)Cl>>COC(=O)C(c1ccc(Cl)cc1)n1ccc2c(NS(C)(=O)=O)cccc21,,ClCCl,,CCN(CC)CC,O,test
US20110263647A1,CC(C)(C)OC(=O)NC(C#Cc1nc(CO)cs1)Cc1ccc(C(F)(F)F)cc1>>CC(C)(C)OC(=O)NC(CCc1nc(CO)cs1)Cc1ccc(C(F)(F)F)cc1,[Pd],CCO,,,,test
US20100222299A1,COc1cc2c(cc1OCc1ccccc1)CC(C)N(C(C)=O)C2>>COc1cc2c(cc1OCc1ccccc1)CC(C)NC2,,CCO,,[Na+].[OH-],,test
US20100252433A1,CC1=NC=C(CCCN(C)C)C1.COC(OC)OC>>Cc1cc(CCCN(C)C)c(C=O)[nH]1,,O=C(O)C(F)(F)F,,,,test
US20110112190A1,CCCCCCCCCC=CC=CC=CC=CC=C/C=C\C(=O)O.COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(O)c(OC)c2)ccc1O>>CCCCCCCCCC=CC=CC=CC=CC=CC=CC(=O)Oc1ccc(C=CC(=O)CC(=O)C=Cc2ccc(O)c(OC)c2)cc1OC,CN(C)c1ccncc1,ClCCl,O,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20100240642A1,CCOC(=O)c1c(-c2ccc(C(C)(C)C)cc2)c2ccccc2n1Cc1cccc(N2CCSCC2)c1.O=[Os](=O)(=O)=O>>CC(C)(C)c1ccc(-c2c(C(=O)O)n(Cc3cccc(N4CCS(=O)(=O)CC4)c3)c3ccccc23)cc1,O=[Os](=O)(=O)=O,CC(C)=O,O,CCOC(C)=O,[Na+].[OH-],test
US06380215B1,C#C[C@H](CC(=O)O)NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1.OCc1ccc(C(F)(F)F)cc1>>C#C[C@H](CC(=O)OCc1ccc(C(F)(F)F)cc1)NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US05688954,CC(=S)OCCCC[C@@H](O)c1cccnc1.CS(=O)(=O)Cl>>CC(=S)OCCCC[C@@H](OS(C)(=O)=O)c1cccnc1,,ClCCl,,CCN(CC)CC,,test
US20070124152A1,CC(N)CO.CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN(C)C(C)=O)c1=O>>CC(=O)N(C)CCn1c(=O)c(C(=O)NC(C)CO)c(O)c2ncc(Cc3ccc(F)cc3)cc21,,CCO,,,,test
US05952462,CC1(O)CCC2CC1(OB(O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C2(C)C>>O=C(N[C@@H](Cc1ccccc1)B(O)O)OCc1ccccc1,,ClCCl,,ClB(Cl)Cl,,test
US04637988,CI.Cc1cc(C(=O)c2ccc([N+](=O)[O-])cc2)cc(C)c1O>>COc1c(C)cc(C(=O)c2ccc([N+](=O)[O-])cc2)cc1C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050137171A1,CC(C)(C)OC(=O)n1nc(-c2cc3ccc(OCCBr)cc3n2C(=O)OC(C)(C)C)c2cc(OCc3ccccc3)ccc21.CCNCC>>CCN(CC)CCOc1ccc2cc(-c3nn(C(=O)OC(C)(C)C)c4ccc(OCc5ccccc5)cc34)n(C(=O)OC(C)(C)C)c2c1,,CC#N,,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US04647687,N#CC(Cl)=CSC(Cl)=C(Cl)C#N.O=S(=O)(Cl)Cl>>N#CC(Cl)=C(Cl)SC(Cl)=C(Cl)C#N,,CC(Cl)Cl,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20150152108A1,CCOC(=O)CC(N)CC(=O)OCC.O=[N+]([O-])c1ccc(Cl)nc1Cl>>CCOC(=O)CC(CC(=O)OCC)Nc1nc(Cl)ccc1[N+](=O)[O-],,C1CCOC1,,O=C([O-])O.[Na+],,test
US04792563,CC(C)(CO)COCc1ccc(F)c(Oc2ccccc2)c1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCC(C)(C)COCc2ccc(F)c(Oc3ccccc3)c2)cc1,,c1ccncc1,,Cl,,test
US20100317651A1,C[C@H](O)CN(Cc1ccccc1)Cc1ncc(Cl)nc1Cl>>C[C@H]1CN(Cc2ccccc2)Cc2ncc(Cl)nc2O1,,C1CCOC1,,O,[H-].[Na+],test
US20090062360A1,COc1ccccc1N.O=C(Cl)CN1C(=O)C(c2ccc(C(F)(F)F)cc2)=NC12CCCCC2>>COc1ccccc1NC(=O)CN1C(=O)C(c2ccc(C(F)(F)F)cc2)=NC12CCCCC2,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20160039745A1,CCCN(CCC)C[C@@H](C)NC(=O)OC(C)(C)C>>CCCN(CCC)C[C@@H](C)N,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120225062A1,CC(C)(O)c1cc(F)cc(F)c1.CC(C)[Si](OS(=O)(=O)C(F)(F)F)(C(C)C)C(C)C>>CC(C)[Si](OC(C)(C)c1cc(F)cc(F)c1)(C(C)C)C(C)C,,ClCCl,,Cc1cccc(C)n1,,test
US06218376B1,Cc1nc2c(o1)CCc1cc(Cl)ccc1C2(O)c1cn(C)c(=O)[nH]c1=O>>Cc1nc2c(o1)C=Cc1cc(Cl)ccc1C2c1cn(C)c(=O)[nH]c1=O,,O=C(O)C(F)(F)F,,,,test
US20140309244A1,CO/N=C(\C)c1cccc(C#CCO)n1.CS(=O)(=O)Cl>>CO/N=C(\C)c1cccc(C#CCOS(C)(=O)=O)n1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20100286120A1,O=C1c2ccc(F)nc2OCCN1Cc1ccccc1.Oc1ccccc1>>O=C1c2ccc(Oc3ccccc3)nc2OCCN1Cc1ccccc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20090111791A1,CS(=O)(=O)c1cc(Cl)ccc1CN.Fc1ccc(OC2CCNCC2)cc1.O=C(n1ccnc1)n1ccnc1>>CS(=O)(=O)c1cc(Cl)ccc1CNC(=O)N1CCC(Oc2ccc(F)cc2)CC1,,CO,ClCCl,CCN(C(C)C)C(C)C,Cl,test
US05081138,CC(C)c1ccc2c(c1)c(SC(C)(C)C)c(CC(C)(C)C(=O)O)n2Cc1ccc(Cl)cc1>>CC(C)c1ccc2c(c1)c(SC(C)(C)C)c(CC(C)(C)CO)n2Cc1ccc(Cl)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150274696A1,COc1ccc(CSc2c([N+](=O)[O-])cnc(N)c2F)cc1>>COc1ccc(CSc2c(N)cnc(N)c2F)cc1,[Zn],CO,,[Cl-].[NH4+],,test
US20160009744A1,Cc1cc(Cc2cccc(Cl)c2)sc1C(=O)c1cncnc1N[C@@H]1C[C@H](CO)[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)C1.NS(=O)(=O)Cl>>Cc1cc(Cc2cccc(Cl)c2)sc1C(=O)c1cncnc1N[C@@H]1C[C@H](COS(N)(=O)=O)[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)C1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20060257987A1,CC(C)(C)OC(=O)n1cccc1B(O)O.CCc1ccc(OC)c(Br)c1>>CCc1ccc(OC)c(-c2cccn2C(=O)OC(C)(C)C)c1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20100190725A1,CNC(=O)Oc1cc(C[C@H](NC(=O)[C@H](Cc2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)NC(=O)OCc2ccccc2)C(=O)OC)ccc1OCc1ccccc1.ClCc1ccccc1>>CNC(=O)Oc1cc(C[C@H](NC(=O)[C@@H]([NH3+])Cc2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)C(=O)OC)ccc1OCc1ccccc1.[Cl-],[Pd],CCOC(C)=O,CO,[H][H],,test
US05721245,Cn1cc(C2=C(c3c4n(c5ccccc35)CCC(CNC(=O)OC(C)(C)C)C4)C(=O)OC2=O)c2ccccc21.NO>>Cn1cc(C2=C(c3c4n(c5ccccc35)CCC(CNC(=O)OC(C)(C)C)C4)C(=O)N(O)C2=O)c2ccccc21,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US03976633,CNC.N#Cc1ccc(C(F)(F)F)cc1N=NNc1cc(C(F)(F)F)ccc1C#N.O=C(Cl)CCBr>>Br.CC(C(=O)N(N=Nc1cc(C(F)(F)F)ccc1C#N)c1cc(C(F)(F)F)ccc1C#N)N(C)C,,CCOCC,,[H-].[Na+],,test
US20080039450A1,CCN1CC(N)CN1CC.COc1cc(C(=O)O)ccc1Nc1cncc(-c2cc3ccccc3n2C(=O)OC(C)(C)C)n1>>CCN1CC(NC(=O)c2ccc(Nc3cncc(-c4cc5ccccc5[nH]4)n3)c(OC)c2)CN1CC,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,test
US04607039,COC(=O)c1ccccc1NC(=O)Cc1ccccc1C>>Cc1ccccc1-c1c(O)c2ccccc2[nH]c1=O,,Cc1ccccc1,,[H-].[Na+],,test
US20100256156A1,Cc1cc(-c2ccccc2)sc1C(O)C1CCCCC1.O=S(Cl)Cl>>Cc1cc(-c2ccccc2)sc1C(Cl)C1CCCCC1,,Cc1ccccc1,,,,test
US20140031360A1,COC(=O)c1ccc2[nH]cc(-c3cncc(N4CCC(N)CC4)n3)c2c1>>NC1CCN(c2cncc(-c3c[nH]c4ccc(C(=O)O)cc34)n2)CC1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20020156081A1,CN1CCN([C@@H]2CC[C@@H](n3nc(-c4ccc(OCc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1>>CN1CCN([C@@H]2CC[C@@H](n3nc(-c4ccc(O)cc4)c4c(N)ncnc43)CC2)CC1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20040138223A1,CC(C)c1ccc(N(Cc2ccc(N(C)C)cc2)C(=O)C2CCOc3c(C#N)cccc32)cc1.OO>>CC(C)c1ccc(N(Cc2ccc(N(C)C)cc2)C(=O)C2CCOc3c(C(N)=O)cccc32)cc1,,CC(C)=O,,[Na+].[OH-],,test
US20030229120A1,N#Cc1cccc(CBr)c1.Oc1ccc(-c2ccccc2)cc1>>N#Cc1cccc(COc2ccc(-c3ccccc3)cc2)c1,,CN(C)C=O,,[H-].[Na+],,test
US20120277229A1,CC1CN(c2ccc(N)c(N)c2)CCO1.O=Cc1nn(C2CCCCO2)c2ccc([N+](=O)[O-])cc12>>CC1CN(c2ccc3[nH]c(-c4nn(C5CCCCO5)c5ccc([N+](=O)[O-])cc45)nc3c2)CCO1,Cl,C1CCOC1,CCOC(C)=O,O=S([O-])O.[Na+],,test
US20080280875A1,COCOc1cc(CO)cc(OCOC)c1C/C=C/c1ccccc1>>COCOc1cc(C=O)cc(OCOC)c1C/C=C/c1ccccc1,,ClCCl,,c1ccncc1,,test
US20100331366A1,CC(C)N=C=O.CCOC(=O)c1cccc(OCCC2CCNCC2)c1>>CCOC(=O)c1cccc(OCCC2CCN(C(=O)NC(C)C)CC2)c1,,ClCCl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20030171360A1,CCN.N#CN=C(Oc1ccccc1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1>>CCN=C(NC#N)N1CCC(n2c(=O)[nH]c3ccccc32)CC1,,C1CCOC1,,,,test
US20160174558A1,COc1nc(Cl)ccc1-n1ccc(O)n1.Cc1cccc([N+](=O)[O-])c1CBr>>COc1nc(Cl)ccc1-n1ccc(OCc2c(C)cccc2[N+](=O)[O-])n1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US05185339,Clc1ccccc1Cc1ccccn1.OO>>[O-][n+]1ccccc1Cc1ccccc1Cl,,CC(=O)O,,,,test
US20120088748A1,CC(C)(C)OC(=O)N1CCOCC(=O)C1.Clc1ccc([Mg]Br)cc1Cl>>CC(C)(C)OC(=O)N1CCOCC(O)(c2ccc(Cl)c(Cl)c2)C1,,C1CCOC1,,O,,test
US20160221972A1,Brc1nc2ccccc2o1.COC(=O)c1ccc2c(c1)OCCNC2>>COC(=O)c1ccc2c(c1)OCCN(c1nc3ccccc3o1)C2,[Cu]I,OCCO,,,,test
US20090318408A1,CI.[N-]=[N+]=N[C@@H]1CCN(C(=O)OCc2ccccc2)C[C@H]1O>>CO[C@@H]1CN(C(=O)OCc2ccccc2)CC[C@H]1N=[N+]=[N-],,C1CCOC1,CN(C)C=O,[H-].[Na+],[Cl-].[NH4+],test
US04507498,CCCc1c(O)c(Cl)cc(C(C)=O)c1O.CCCc1c(OCC(=O)OC)ccc(C(C)=O)c1OCCCBr>>CCCc1c(O)c(C(C)=O)cc(Cl)c1OCCCOc1c(C(C)=O)ccc(OCC(=O)OC)c1CCC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100331293A1,COc1ccc(-c2ncc(N3CCOCC3)cc2N)cn1.Cc1c(-c2ccccc2S(C)(=O)=O)nc2cc(F)cc(F)c2c1Cl>>COc1ccc(-c2ncc(N3CCOCC3)cc2Nc2c(C)c(-c3ccccc3S(C)(=O)=O)nc3cc(F)cc(F)c23)cn1,,Cc1ccccc1,,,,test
US05089504,CCCC(=O)c1cnc2c(C=O)cccc2c1Nc1ccc(O)cc1C.C[Mg]I>>CCCC(=O)c1cnc2c(C(C)O)cccc2c1Nc1ccc(O)cc1C,,C1CCOC1,CCOCC,,,test
US04622401,CCOCCC#N.NNc1ccc(Cl)cn1>>NC1=NN(c2ccc(Cl)cn2)CC1,,CCO,,[Na],,test
US05283241,CNC.O=C=Nc1ccccc1-c1ccc(COC2CCCCO2)cc1>>CN(C)C(=O)Nc1ccccc1-c1ccc(CO)cc1,,CO,,,,test
US04959092,CC1(C)Cc2cc(COc3ccc(N)cc3)ccc2O1.CON(C)C(=O)Cl>>CON(C)C(=O)Nc1ccc(OCc2ccc3c(c2)CC(C)(C)O3)cc1,,c1ccncc1,,,,test
US20040138286A1,CCCCP(=CC#N)(CCCC)CCCC.CCc1c(O)ccc2[nH]ncc12>>CC(C)c1c(O)ccc2[nH]ncc12,,Cc1ccccc1,,,,test
US20070060563A1,CCc1cc2c(cc1CC)CC(N)C2.CN(C)C(On1nnc2cccnc21)=[N+](C)C.CN(C)C=O.F[P-](F)(F)(F)(F)F.O=C(O)C[N+]12CCC(CC1)[C@@H](OC(=O)C(O)(c1ccccc1)c1ccccc1)C2.O=C([O-])C(F)(F)F>>CCc1cc2c(cc1CC)CC(NC(=O)C[N+]13CCC(CC1)[C@@H](OC(=O)C(O)(c1ccccc1)c1ccccc1)C3)C2.O=C(O)C(F)(F)F.O=C([O-])C(F)(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20140088078A1,COC(=O)c1c(NC(=O)C(C)(C)C)ccc(-c2ccoc2CO[Si](C)(C)C(C)(C)C)c1NC(C)=O>>COC(=O)c1c(NC(=O)C(C)(C)C)ccc(-c2ccoc2CO)c1NC(C)=O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20070155839A1,COc1cccc(C(=O)c2ccc(Br)c(F)c2)c1>>O=C(c1cccc(O)c1)c1ccc(Br)c(F)c1,,Cc1ccccc1,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US05892039,ClCCl.FC(F)(F)C(Br)(c1ccccc1)C(F)(F)F.c1ccc(C2CNCCN2)cc1>>FC(F)(F)c1cc(CN2CCNC(c3ccccc3)C2)cc(C(F)(F)F)c1,,ClCCl,,CCN(CC)CC,,test
US04009166,CI.O=C1NCc2cccnc2N1c1cccc(C(F)(F)F)c1>>CN1Cc2cccnc2N(c2cccc(C(F)(F)F)c2)C1=O,,CN(C)C=O,,[H-].[Na+],,test
US05583130,CCOC(=O)Cc1c[nH]cn1.C[Si](C)(C)CCOCCl>>CCOC(=O)Cc1cn(COCC[Si](C)(C)C)cn1,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US06353006B1,CC(C)CC1COC(C(C)C)N1>>CC(C)CN[C@H](CO)CC(C)C,,CCO,,[BH4-].[Na+],,test
US20140010783A1,CS/C(=N\C#N)Nc1ccc(C(=O)N(C)C)cc1.NN>>CN(C)C(=O)c1ccc(Nc2n[nH]c(N)n2)cc1,,CCO,,,,test
US05312824,COc1ccnc(CSc2nc3ccccc3[nH]2)c1C>>Cc1c(O)ccnc1CSc1nc2ccccc2[nH]1,,Br,,,,test
US20150191483A1,O=C1CCC1.O=S(=O)(c1cccc(Br)c1)C1(c2ccc(C(F)(C(F)(F)F)C(F)(F)F)cc2)CCN(Cc2ccccc2)C1>>O=S(=O)(c1cccc(C2(O)CCC2)c1)C1(c2ccc(C(F)(C(F)(F)F)C(F)(F)F)cc2)CCN(Cc2ccccc2)C1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US05755991,CC(C)(O)C(=O)c1ccccc1.O=C=NS(=O)(=O)Cl>>CC(C)(C(N)=O)C(=O)c1ccccc1,,Cc1ccccc1,,,,test
US20070293526A1,N#Cc1cccc2cc(S(=O)(=O)c3ccccc3)ccc12>>NCc1cccc2cc(S(=O)(=O)c3ccccc3)ccc12,,C1CCOC1,,,,test
US20010027196A1,COCCN.Nc1nc(OS(=O)(=O)C(F)(F)F)c([N+](=O)[O-])c(-c2ccco2)n1>>COCCNc1nc(N)nc(-c2ccco2)c1[N+](=O)[O-],,COCCOC,,,,test
US05062884,CCOC(=O)CC(=O)[O-].O=Cc1cc([N+](=O)[O-])ccc1Cl>>CCOC(=O)C=Cc1cc([N+](=O)[O-])ccc1Cl,,c1ccncc1,,,,test
US05281585,CC(O)C1CN(C(=O)OC(C)(C)C)C1.II>>CC(C)(C)OC(=O)N1CC(CCI)C1,,CC#N,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120178934A1,COC(=O)[C@H](CNC(=O)c1ccc(OC)cc1)N1CCN(S(C)(=O)=O)CC1>>COc1ccc(C(=O)NC[C@@H](C(=O)O)N2CCN(S(C)(=O)=O)CC2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US04937306,O=C(c1ccc([N+](=O)[O-])cc1[N+](=O)[O-])N1CCOCC1>>Nc1ccc(C(=O)N2CCOCC2)c(N)c1,[Pd],CO,,[H][H],,test
US04242507,O=S(=O)(Cl)c1ccccc1.O=c1c2ccccc2nnn1O>>O=c1c2ccccc2nnn1OS(=O)(=O)c1ccccc1,,CCOC(C)=O,O,O=C([O-])O.[Na+],,test
US20160000760A1,CC(C)(C)OC(=O)N1CCCC(CBr)C1.Sc1ccc(Br)cc1>>CC(C)(C)OC(=O)N1CCCC(CSc2ccc(Br)cc2)C1,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140249126A1,COc1cc2c(=O)c(C(=O)O)cn(C3CC3)c2cc1OC>>O=C(O)c1cn(C2CC2)c2cc(O)c(O)cc2c1=O,,CO,ClCCl,BrB(Br)Br,,test
US05043142,COCCOCCl.OCc1cc(Br)ccc1Cl>>COCCOCOCc1cc(Br)ccc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,[Cl-].[NH4+],test
US20150203487A1,C=CCn1c(S(C)(=O)=O)nc2nc(-c3ccc(-c4ccccc4)cc3)c(Cl)cc21.OC1COCC1O>>C=CCn1c(OC2COCC2O)nc2nc(-c3ccc(-c4ccccc4)cc3)c(Cl)cc21,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20030092677A1,CC(C)(C)OC(=O)Nc1ccc(-c2ccc(-c3ccccc3)cc2)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1ccc(-c2ccc(-c3ccccc3)cc2)cc1N,[Pd],,,,,test
US20130023526A1,COc1cc(CNC(=O)c2cc(C3=NOC(c4cn(C(c5ccccc5)(c5ccccc5)c5ccccc5)cn4)C3)nc(C)n2)ccc1F>>COc1cc(CNC(=O)c2cc(C3=NOC(c4c[nH]cn4)C3)nc(C)n2)ccc1F,,CO,,Cl,,test
US04866091,CNC(=O)c1ccc([N+](=O)[O-])c(Oc2ccc(F)cc2F)c1>>CNC(=O)c1ccc(N)c(Oc2ccc(F)cc2F)c1,[Fe],CCO,O,[Cl-].[NH4+],,test
US06291640B1,C[C@H](NC(=O)OCc1ccccc1)C(O)c1nc2ccccc2o1.Cc1cccc(O)c1N>>Cc1cccc2oc(C(O)[C@H](C)NC(=O)OCc3ccccc3)nc12,,CCOC(C)=O,,[Br-].[K+],,test
US20140335201A1,C1CCOC1.CC(C)OC(=O)[N+](=[N-])C(=O)OC(C)C.Cc1nc(O)c(Br)cc1[N+](=O)[O-].c1ccc(P(c2ccccc2)c2ccccc2)cc1>>Cc1nc(O[C@@H]2CC[C@@H](C(C)C)CC2)c(Br)cc1[N+](=O)[O-],,C1CCOC1,,,,test
US20090099207A1,COCCc1cc(C[C@@H]2CS(=O)(=O)C[C@H](NCc3cccc(C(C)C)c3)[C@H]2O)ccc1OC>>CC(C)c1cccc(CN[C@H]2CS(=O)(=O)C[C@@H](Cc3ccc(O)c(CCO)c3)[C@@H]2O)c1,,CO,ClCCl,BrB(Br)Br,,test
US20080287428A1,CC(C)(C)OC(N)=O.CC(C)(C)OC(N)=O.Nc1ccc(C(F)(F)F)cc1>>CC(C)(C)c1cc(C(F)(F)F)ccc1OC(N)=O,,C1CCOC1,,,,test
US20160030585A1,O=C(O)CCCCCCCCCCC(CCCCCCCCCCCOC(c1ccccc1)(c1ccccc1)c1ccccc1)(C(=O)O)C(=O)O.O=C1CCC(=O)N1O>>O=C(O)CCCCCCCCCCC(CCCCCCCCCCCOC(c1ccccc1)(c1ccccc1)c1ccccc1)(C(=O)O)C(=O)ON1C(=O)CCC1=O,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04749704,COC(=O)C1CCC(OC)C1=O.NC(N)=S>>COC1CCc2c1nc(S)[nH]c2=O,,CCO,O,Cl,[K+].[OH-],test
US05739345,Cn1c(CCCO)nc2cccnc21.O=C1SC(Cc2ccc(O)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1>>Cn1c(CCCOc2ccc(CC3SC(=O)N(C(c4ccccc4)(c4ccccc4)c4ccccc4)C3=O)cc2)nc2cccnc21,,Cc1ccccc1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20160115119A1,N[C@@H]1CCc2c(F)cc(Cl)cc21.O=C(O)c1cccnc1[N+](=O)[O-].O=Cc1ccccc1.[C-]#[N+]C1=CCC(c2ccccc2)CC1>>NC(=O)[C@@H](c1ccccc1)N(C(=O)c1cccnc1[N+](=O)[O-])[C@@H]1CCc2c(F)cc(Cl)cc21,,CCN(CC)CC,,CO,Cl,test
US03966746,CCI.CCOC(=O)c1cnc2[nH]ncc2c1O>>CCOC(=O)c1cnc2[nH]ncc2c1OCC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080146539A1,Cc1cc(C(=O)O)ccc1N1CCOCC1=O.NC(c1cccnc1)c1nc2cc(Cl)ccc2[nH]1>>Cc1cc(C(=O)NC(c2cccnc2)c2nc3cc(Cl)ccc3[nH]2)ccc1N1CCOCC1=O,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US08252933B2,CC(C)OC(=O)Cl.Nc1cccc(Cl)c1C(=O)O>>O=c1[nH]c2cccc(Cl)c2c(=O)o1,,C1COCCO1,,CC(=O)Cl,,test
US06252080B1,NCc1ccc(Cl)cc1.O=C(O)c1ccc2cccnc2c1O>>O=C(NCc1ccc(Cl)cc1)c1ccc2cccnc2c1O,,O,,ClP(Cl)Cl,,test
US20070123543A1,Cc1nc2c(O)cccc2s1.O=[N+]([O-])c1cccc(S(=O)(=O)OC[C@@H]2CO2)c1>>Cc1nc2c(OC[C@@H]3CO3)cccc2s1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120202852A1,COc1ccc(C(NC(=O)Cc2ccc(C3CC3)cc2)c2c[nH]c(C)n2)cc1>>Cc1nc(C(NC(=O)Cc2ccc(C3CC3)cc2)c2ccc(O)cc2)c[nH]1,,ClCCl,,BrB(Br)Br,,test
US20080194629A1,CCCCCCC1(CN=[N+]=[N-])c2ccccc2Oc2ccccc21>>CCCCCCC1(CN)c2ccccc2Oc2ccccc21,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120149718A1,CC(=O)OCc1cnc(NC(=O)OC(C)(C)C)cn1>>CC(=O)OCc1cnc(N)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090281103A1,COC/C=C/c1cc(C=O)cc(O[Si](C)(C)C(C)(C)C)c1>>COCCCc1cc(C=O)cc(O[Si](C)(C)C(C)(C)C)c1,[Pd],CCOC(C)=O,,,,test
US20140114068A1,CC(C)c1ccc2c(c1)OC1(O)c3cccc([N+](=O)[O-])c3C(=O)C21NC(=O)c1ccc(Cl)cc1>>CC(C)c1ccc2c(c1)OC1(O)c3cccc(N)c3C(=O)C21NC(=O)c1ccc(Cl)cc1,[Fe],CCO,O,,,test
US20060234997A1,COc1ccc2c(c1)NC(=O)N(C)CC2>>CN1CCc2ccc(O)cc2NC1=O,,ClCCl,,BrB(Br)Br,,test
US20130158056A1,COC(=O)/C=C/c1ccc2ccccc2n1>>OCCCc1ccc2ccccc2n1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05082951,CCOC(=O)CC(=O)OCC.O=C(c1ccccc1)c1cccn1CCI>>CCOC(=O)C(CCn1cccc1C(=O)c1ccccc1)C(=O)OCC,,CN(C)C=O,,O,[H-].[Na+],test
US20100120785A1,CS(=O)(=O)Cl.Cc1n[nH]c(C)c1CN1CCN(c2nccnc2-c2ccc(F)cc2)CC1>>Cc1nn(S(C)(=O)=O)c(C)c1CN1CCN(c2nccnc2-c2ccc(F)cc2)CC1,,c1ccncc1,,,,test
US03951986,COc1ccccc1N1CCN(CC(O)CSc2ccc(F)cc2)CC1.OO>>COc1ccccc1N1CCN(CC(O)CS(=O)c2ccc(F)cc2)CC1,,CC(=O)O,,N,O,test
US20030069427A1,O=c1oc2cccc(O)c2c2ccc([N+](=O)[O-])cc12>>Nc1ccc2c(c1)c(=O)oc1cccc(O)c12,,CN1CCCC1=O,,,,test
US20110021522A1,COc1ccc(-c2cccc(N)c2)cc1C.O=C(O)c1cc2cccc(O)c2oc1=O>>COc1ccc(-c2cccc(NC(=O)c3cc4cccc(O)c4oc3=O)c2)cc1C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100105650A1,COc1ccc(Cn2ccc3cc(SC4CCN(C(=O)OC(C)(C)C)CC4)c(Cl)cc3c2=O)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(Cn2ccc3cc(S(=O)C4CCN(C(=O)OC(C)(C)C)CC4)c(Cl)cc3c2=O)cc1,,ClCCl,,,,test
US20020119992A1,COc1ccc(NC(Cc2ccc(Cl)cc2CNC(=O)[C@@H]2CCCN2C(=O)OC(C)(C)C)C(F)F)cc1>>COc1ccc(NC(Cc2ccc(Cl)cc2CNC(=O)[C@@H]2CCCN2)C(F)F)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100056521A1,N#Cc1c[nH]c2ccccc12.O=Cc1ccc(Br)o1>>N#Cc1cn(-c2ccc(C=O)o2)c2ccccc12,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US05206266,CCON=Cc1ccccc1O.COC=C(C(=O)OC)c1ccccc1CBr>>CCON=Cc1ccccc1OCc1ccccc1C(=COC)C(=O)OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110184188A1,Cc1cc(CN2N=C(C(F)(F)C(F)(F)F)NC2(O)c2ccc(Cl)cc2)ccc1[N+](=O)[O-]>>Cc1cc(Cn2nc(C(F)(F)C(F)(F)F)nc2-c2ccc(Cl)cc2)ccc1[N+](=O)[O-],,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US20060235222A1,CCC(O)(CC)c1ccc(O)c(NC(C)=O)c1.CS(=O)(=O)Nc1cccc2cc[nH]c12>>CCC(CC)(c1ccc(O)c(NC(C)=O)c1)c1c[nH]c2c(NS(C)(=O)=O)cccc12,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US05028606,Nc1ccc(C(c2cccc(F)c2)n2ccnc2)cc1N.O=CC=O>>Fc1cccc(C(c2ccc3nccnc3c2)n2ccnc2)c1,,CO,,,,test
US20150119385A1,COC(OC)c1ccc2c(n1)N(C(=O)Nc1cc(C#N)c(C#N)cn1)CCC2>>N#Cc1cnc(NC(=O)N2CCCc3ccc(C=O)nc32)cc1C#N,,C1CCOC1,CCOC(C)=O,Cl,O,test
US04760064,COc1ccc(C(=O)N2CCN(c3ccc4c(c3)CCC(=O)N4Cc3ccc(OC(C)=O)cc3)CC2)cc1OC>>COc1ccc(C(=O)N2CCN(c3ccc4c(c3)CCC(=O)N4Cc3ccc(O)cc3)CC2)cc1OC,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20150329524A1,CCC(=O)N1CC[C@@H](CC(=O)NN)C1.O=C=Nc1ccc(Br)cc1F>>CCC(=O)N1CC[C@@H](CC(=O)NNC(=O)Nc2ccc(Br)cc2F)C1,,ClCCl,,,,test
US20030216390A1,C1CCNCC1.Cc1cccc(C#N)c1Br>>N#Cc1ccccc1CN1CCCCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04186135,O=C(O)c1cc([N+](=O)[O-])cc2c1OCCO2>>Nc1cc2c(c(C(=O)O)c1)OCCO2,[Ni],O,,CCO,[H][H],test
US04592866,CN1CC(CCCl)Oc2ccc(F)cc2C1=O.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CN1CC(CCCl)Oc2ccc(F)cc2C1=S,,CC#N,Cc1ccccc1,,,test
US20070219181A1,Cc1ccc(CC(=O)O)cc1.ClCCCBr>>Cc1ccc(C(CCCCl)C(=O)O)cc1,,C1CCOC1,CCOC(C)=O,Cl,[Li]CCCC,test
US05030629,CC(N)CN.CCCCCCCCCCCC#N>>CCCCCCCCCCCC1=NC(C)CN1,,S=C=S,,,,test
US05399589,CCONC(=O)C(=O)OC.NN>>CCONC(=O)C(=O)NN,,CCO,,O,,test
US20080091034A1,CC(C)N(C(=O)CCCOCCO)C1CCN(Cc2ccccc2)CC1>>CC(C)N(CCCCOCCO)C1CCN(Cc2ccccc2)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070293515A1,CC(C)(C)OC(=O)N[C@H]1CCNC1.Cc1ccc(-c2noc(C(Cl)(Cl)Cl)n2)cc1>>Cc1ccc(-c2noc(N3CC[C@H](NC(=O)OC(C)(C)C)C3)n2)cc1,,CN1CCCC1=O,,,,test
US05234936,CC(=N)N.CCOC(=O)C1CCCCC1=O>>Cc1nc2c(c(=O)[nH]1)CCCC2,,CCO,,Cl,[Na],test
US20120208817A1,CCOc1cc(C2NC(=O)NC(c3ccc(Br)cc3)=C2c2ccccc2)cc([N+](=O)[O-])c1O.CCOc1cc(C=O)cc([N+](=O)[O-])c1O.NC(N)=O>>CCOc1cc(C2NC(=O)NC(c3ccccc3)=C2c2ccccc2C#N)cc([N+](=O)[O-])c1O,,CCO,,Cl,,test
US20150376160A1,CCOC(=O)C1(c2ccc(-c3ccc(-c4sccc4C(N)=O)cc3)cc2)CC1.O=C1CCC(=O)N1Cl>>CCOC(=O)C1(c2ccc(-c3ccc(-c4sc(Cl)cc4C(N)=O)cc3)cc2)CC1,,CN(C)C=O,,O,,test
US04097587,C=O.CCC1(C)CC2(NC(=O)N(C)C2=O)C(C)C(C)(CC)N1>>CCC1(C)CC2(NC(=O)N(C)C2=O)C(C)C(C)(CC)N1C,,O=CO,,O=C([O-])O.[Na+],,test
US20100015053A1,COC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(F)c(C(F)(F)F)c2)c2sc3ccccc3c2C)cc1>>Cc1c(N(Cc2ccc(F)c(C(F)(F)F)c2)S(=O)(=O)c2ccc(C(=O)O)cc2)sc2ccccc12,,CCOC(C)=O,Cl,CO,[Na+].[OH-],test
US06252080B1,Cc1ccc2c(Cl)ccc(O)c2n1.ClI>>Cc1ccc2c(Cl)cc(I)c(O)c2n1,,CO,,,,test
US04145432,CCOC(=O)C1=C(C)NC(C=O)=C(C(=O)OCC)C1c1ccccc1[N+](=O)[O-].CN(C)CCCN>>CCOC(=O)C1=C(C)NC(C=NCCCN(C)C)=C(C(=O)OCC)C1c1ccccc1[N+](=O)[O-],,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040082542A1,CCN(CC)CCCOc1cccc([N+](=O)[O-])c1>>CCN(CC)CCCOc1cccc(N)c1,[Pd],CO,,,,test
US20160264570A1,CC(C)(C)OC(=O)N1CCN(c2ccc(N)cc2C(F)(F)F)CC1.CCOC(=O)c1cnc2ccc(Br)cc2c1Cl>>CCOC(=O)c1cnc2ccc(Br)cc2c1Nc1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)c(C(F)(F)F)c1,,C1CCOC1,,CCOC(C)=O,,test
US20120295884A1,CC(C)(C)OC(=O)Cn1cc(C(N)=O)c2cc(Cl)ccc21>>NC(=O)c1cn(CC(=O)O)c2ccc(Cl)cc12,,ClCCl,,CO,O=C(O)C(F)(F)F,test
US20090221567A1,CC(C)(C)OC(=O)N1CCC(N2CCC(N3C(=O)NC[C@H]4CCCC[C@@H]43)CC2)CC1.Cl>>Cl.O=C1NC[C@H]2CCCC[C@@H]2N1C1CCN(C2CCNCC2)CC1,,CO,,C1COCCO1,,test
US20150239900A1,CC(=O)Cl.COC(=O)c1cc(I)c(Cl)cc1N>>COC(=O)c1cc(I)c(Cl)cc1NC(C)=O,,ClCCl,,c1ccncc1,,test
US20120329785A1,CN1CCN(c2ccc(N)cc2)CC1.COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccccc23)cc1>>CN1CCN(c2ccc(Nc3nc4ccccc4c4c[nH]nc34)cc2)CC1,C1COCCO1,CO,,Cl,,test
US20060264429A1,CO.Cc1ccc2c(N3CCN(CCC(O)c4ccc5c(c4)NC(=O)CO5)CC3)cccc2n1>>COC(CCN1CCN(c2cccc3nc(C)ccc23)CC1)c1ccc2c(c1)NC(=O)CO2,,O=C(O)C(F)(F)F,,,,test
US20120190677A1,COC(=O)c1cc(Cl)cc2c1NC(c1cccc(Br)c1)CC2(C)C.O=C1NCCO1>>CC1(C)CC(c2cccc(N3CCOC3=O)c2)Nc2c(C(=O)O)cc(Cl)cc21,[Cu]I,CS(C)=O,,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US20070167468A1,CS(N)(=O)=O.C[N+]1([O-])CCOCC1.OCCC=CCCO>>OCCC(O)C(O)CCO,,CC(C)(C)O,O,CC(C)=O,,test
US20040006099A1,BrC(Br)(Br)Br.O=C(OCc1ccccc1)N1CCC(CO)CC1>>O=C(OCc1ccccc1)N1CCC(CBr)CC1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060100436A1,COc1c(N2CCC(C)C(N)C2)ccc2c(=O)c(C(=O)O)cn(C3CC3)c12.Cl>>COc1c(N2CCC(C)C(N)C2)ccc2c(=O)c(C(=O)O)cn(C3CC3)c12.Cl,,CCO,,,,test
US20150218096A1,COC(=O)c1ccc(-c2n[nH]c3cccnc23)c(F)c1.Cc1cc(Br)cc(Cl)c1C(=O)Cl>>COC(=O)c1ccc(-c2nn(C(=O)c3c(C)cc(Br)cc3Cl)c3cccnc23)c(F)c1,CN(C)c1ccncc1,ClCCl,,CCOC(C)=O,,test
US20090004185A1,Cc1ccc2c(Cl)nc(Cl)nc2c1.NCc1ccc(NC(=O)c2ccc(Br)cc2)cc1>>Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(Br)cc4)cc3)nc(Cl)nc2c1,,C1CCOC1,,CCN(CC)CC,,test
US04061670,C#CCBr.CCCCC(=O)C1CC1>>C#CCC(O)(CCCC)C1CC1,,CCOCC,,[Mg],[Cl-].[NH4+],test
US03931209,C=O.CCN(N)C(=O)Nc1nnc(C)s1>>CCN1NCN(c2nnc(C)s2)C1=O,,CO,,[K+].[OH-],,test
US20100016387A1,C[Si](C)(C)C(F)(F)F.Cc1cccc(C)c1-c1nc2ccc(C=O)cc2n1C(=O)OC(C)(C)C>>Cc1cccc(C)c1-c1nc2ccc(C(O)C(F)(F)F)cc2n1C(=O)OC(C)(C)C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140349993A1,CC1(CO)COC1.Nc1ccnc(Cl)n1>>CC1(COc2nccc(N)n2)COC1,,CCCCC,,[H-].[Na+],,test
US05374615,CCCCc1nc(Cl)c(C=O)[nH]1.N#Cc1ccccc1-n1cnc2c(CBr)cccc21>>CCCCc1nc(Cl)c(C=O)n1Cc1cccc2c1ncn2-c1ccccc1C#N,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05171748,CCCCc1nc2ccccc2n1Cc1ccc(-c2ccccc2C(=O)OC)cc1>>CCCCc1nc2ccccc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1,,CCO,,[Na+].[OH-],,test
US20090137573A1,CCOC(=O)c1c(-c2ccc(C)cc2)c(C)cn1Cc1ccc(C)cc1>>Cc1ccc(Cn2cc(C)c(-c3ccc(C)cc3)c2C(=O)O)cc1,,CO,O,[Na+].[OH-],,test
US20160052922A1,C1COCCN1.CCOC(=O)c1c(Cl)c2cnn(C(C)C)c2[nH]c1=O>>CCOC(=O)c1c(N2CCOCC2)c2cnn(C(C)C)c2[nH]c1=O,,CC#N,,,,test
US20050137196A1,COc1ccc(N)cc1Cl.Clc1nc(Cl)nc(Cl)n1.NC1CCCCCC1>>COc1ccc(Nc2nc(Cl)nc(NC3CCCCCC3)n2)cc1Cl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090028925A1,COCOc1ccc(C=O)cc1C(C)C.Cc1cc(O[Si](C(C)C)(C(C)C)C(C)C)c(C)c(C)c1Br>>COCOc1ccc(C(O)c2c(C)cc(O[Si](C(C)C)(C(C)C)C(C)C)c(C)c2C)cc1C(C)C,,C1CCOC1,,[Li]CCCC,,test
US20050267093A1,CO.COc1cc(N)ccc1OCCN1CCc2ccccc2C1.O=C(O)C#Cc1ccc(C(F)(F)F)cc1Cl>>COc1cc(NC(=O)C#Cc2ccc(C(F)(F)F)cc2Cl)ccc1OCCN1CCc2ccccc2C1.O=CO,,CO,ClCCl,,,test
US20040009968A1,N#Cc1cc([N+](=O)[O-])ccc1F.NN>>Nc1n[nH]c2ccc([N+](=O)[O-])cc12,,CCO,,O,,test
US20090298836A1,CNc1cc(-c2nnc(N(C[C@H](Cc3ccc(C(F)(F)F)cc3)NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)s2)ccc1[N+](=O)[O-]>>CNc1cc(-c2nnc(N(C[C@H](Cc3ccc(C(F)(F)F)cc3)NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)s2)ccc1N,[Pd],CO,,CC(=O)O,O,test
US20140350244A1,Nc1cc(Cl)c(I)cn1.OB(O)c1ccncc1Cl>>Nc1cc(Cl)c(-c2ccncc2Cl)cn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,ClCCl,O=C([O-])[O-].[Na+].[Na+],test
US20080234501A1,CC(O)CO.Cc1ccc(C)c(C(=O)CCl)c1>>Cc1ccc(C)c(C2(CCl)OCC(C)O2)c1,,Cc1ccccc1C,,,,test
US06458781B1,CC(C)C[C@@H](C(=O)O)N1CCOCC1.Cl.NCCCC(c1ccc(F)cc1)c1ccc(F)cc1>>CC(C)C[C@@H](C(=O)NCCCC(c1ccc(F)cc1)c1ccc(F)cc1)N1CCOCC1.Cl,,CCOCC,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US08629168B2,CCN1CCNCC1.Cc1cc([N+](=O)[O-])ccc1CBr>>CCN1CCN(Cc2ccc([N+](=O)[O-])cc2C)CC1,,ClCCl,,CCN(CC)CC,,test
US20070015757A1,CC(C)(C)OC(=O)Nc1ccc(C(=O)NCCC(=O)O)cc1.O=C(O)C(F)(F)F>>Nc1ccc(C(=O)NCCC(=O)O)cc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US04814332,COc1ccc(-c2nccn2N=Cc2ccc(N(C)C)cc2)cc1.COc1ccc(C(=O)CBr)cc1>>COc1ccc(C(=O)C[n+]2ccn(N=Cc3ccc(N(C)C)cc3)c2-c2ccc(OC)cc2)cc1.[Br-],,CC(C)O,,,,test
US20070259851A1,CC(C)(C)C(=O)Cl.COC(=O)c1sccc1N>>CC(C)(C)C(=O)Nc1ccsc1,,c1ccncc1,,,,test
US05690957,CCCCCCCCCCCC(=O)Cl.OCCO>>CCCCCCCCCCCC(=O)OCCO,,c1ccncc1,,CC(C)=O,,test
US20060100425A1,BrCc1ccccc1.CC(C)(C)OC(=O)CBr.O=S1(=O)NN=C(c2c[nH]c3ccccc23)c2ccccc21>>O=C(O)Cn1cc(C2=NN(Cc3ccccc3)S(=O)(=O)c3ccccc32)c2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US03995052,CC1(CO)OCCC2=C1Cc1ccccc12.Cc1ccc(S(=O)(=O)Cl)cc1>>CC1OCCC2=C1Cc1ccccc12.COS(=O)(=O)c1ccc(C)cc1,,c1ccncc1,,O,,test
US04826814,CC(C)(C)O.O=C(O)[C@@H]1Cc2ccccc2N1C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)[C@@H]1Cc2ccccc2N1C(=O)OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,O,,test
US20040058903A1,Cc1cccc(B(O)O)c1.O=C(Nc1ccc(NCCc2ccccn2)cc1)c1ccccc1I>>Cc1cccc(-c2ccccc2C(=O)Nc2ccc(NCCc3ccccn3)cc2)c1,,CN(C)C=O,,CCN(CC)CC,CCOC(C)=O,test
US05026836,Nc1cc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=S)[nH]1.[NH4+]>>NSc1nc(N)cc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O,,[K+],[OH-],[Na+].[O-]Cl,,test
US20110046169A1,Cc1c(NC(=O)C2CC2)nc2ccc(Oc3ccc([N+](=O)[O-])cc3F)cn12>>Cc1c(NC(=O)C2CC2)nc2ccc(Oc3ccc(N)cc3F)cn12,,CCO,CCOC(C)=O,O,[Cl-].[NH4+],test
US03950356,C=C1N(C)c2ccccc2C1(C)C.CCO.O=Cc1c(O)ccc2cc([N+](=O)[O-])ccc12>>C1=COC2(C=C1)Cc1ccccc1N2,,CCO,,,,test
US04397677,CCOC(CN(CC)c1c([N+](=O)[O-])cc(C)cc1[N+](=O)[O-])OCC.OCCO>>CCN(CC1OCCO1)c1c([N+](=O)[O-])cc(C)cc1[N+](=O)[O-],,CCOC(C)=O,,Cc1ccccc1S(=O)(=O)O,,test
US20100168154A1,O=C(Cl)C(=O)Cl.O=C(NCCc1ccc(Cl)cc1)C1CCCCC1>>O=C1OC2(C3CCCCC3)c3cc(Cl)ccc3CCN2C1=O,,ClCCCl,,Cl,,test
US20110257151A1,CCOC(=O)c1ccc(N)cc1.O=Cc1cc(F)cc(F)c1>>CCOC(=O)c1ccc(N=Cc2cc(F)cc(F)c2)cc1,,CCO,,,,test
US20120302539A1,CC(C)(C)OC(=O)NC1CCNCC1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1Cl>>CC(C)(C)OC(=O)NC1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])c(Cl)c2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05567843,O=[N+]([O-])c1cccc(-c2nc3cc([N+](=O)[O-])ccc3o2)c1>>Nc1cccc(-c2nc3cc(N)ccc3o2)c1,[Pd],CCCO,,,,test
US20070259877A1,COc1ccc(N2C[C@H](C)N[C@H](C)C2)cc1NS(=O)(=O)c1ccc(Br)cc1.Cc1csc(B(O)O)c1>>COc1ccc(N2C[C@H](C)N[C@H](C)C2)cc1NS(=O)(=O)c1ccc(-c2cc(C)cs2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,CC(C)(C)[O-].[K+],,test
US20120094996A1,CC(=O)Nc1cccc(-c2nn3c(I)cnc3s2)c1.CC1(C)OB(c2cnc(N)c(C(F)(F)F)c2)OC1(C)C>>CC(=O)Nc1cccc(-c2nn3c(-c4cnc(N)c(C(F)(F)F)c4)cnc3s2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20020120007A1,Nc1ccc(F)cc1.O=C(Cl)c1ccccc1[N+](=O)[O-]>>O=C(Nc1ccc(F)cc1)c1ccccc1[N+](=O)[O-],,ClCCl,,c1ccncc1,,test
US20060287291A1,Cc1cc([N+](=O)[O-])cc2ccoc12.O=C1CCC(=O)N1Br>>O=[N+]([O-])c1cc(CBr)c2occc2c1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US05840751,CN(Cc1ccccc1)C(=O)CCCC(=O)c1ccccc1.COC(=O)CC(C)=O>>CN(Cc1ccccc1)C(=O)CCCC1(c2ccccc2)CC(O)=CC(=O)O1,,C1CCOC1,CCCCCC,[Li]CCCC,[H-].[Na+],test
US20060205767A1,COc1ccc(-c2cc(=O)c3ccccc3o2)c([N+](=O)[O-])c1>>COc1ccc(-c2cc(=O)c3ccccc3o2)c(N)c1,,CCO,O,Cl[Sn]Cl,,test
US20080058321A1,CCO.N#Cc1ccc(S)c(Br)c1>>CCOC(=N)c1ccc(S)c(Br)c1,,Cc1ccccc1,ClC(Cl)Cl,,,test
US06248755B1,CC(C)(C)[Si](C)(C)OC[C@H]1CN([C@H](CC2CCC2)C(=O)OCc2ccccc2)C[C@@H]1c1ccccc1>>O=C(OCc1ccccc1)[C@@H](CC1CCC1)N1C[C@H](c2ccccc2)[C@@H](CO)C1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20060252790A1,CCn1ncc2c(NC3CCOCC3)c(-c3nc(CC4CCNCC4)no3)cnc21.CS(=O)(=O)Cl>>CCn1ncc2c(NC3CCOCC3)c(-c3nc(CC4CCN(S(C)(=O)=O)CC4)no3)cnc21,,ClC(Cl)Cl,,Cl,c1ccncc1,test
US04375471,CCOC(=O)Cl.CN1Cc2ccccc2C(Oc2ccc([N+](=O)[O-])cc2)C1>>CCOC(=O)N1Cc2ccccc2C(Oc2ccc([N+](=O)[O-])cc2)C1,,CCOCC,c1ccccc1,O=C([O-])[O-].[K+].[K+],,test
US05637780,COCCOCCl.OCc1ccc(CCl)cc1>>COCCOCOCc1ccc(CCl)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04551171,CC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].CN>>CN=C(C)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-],,CCO,,,,test
US09181244B1,O=[N+]([O-])c1cccc(Sc2cccnc2)c1>>Nc1cccc(Sc2cccnc2)c1,[Pd],C1CCOC1,,[H][H],,test
US05021443,CCOC(=O)CC(C)(C)Cc1nc2ccccc2[nH]1.ClCc1ccc(Cl)cc1>>CCOC(=O)CC(C)(C)Cc1nc2ccccc2n1Cc1ccc(Cl)cc1,,CN(C)C=O,,[H-].[Na+],,test
US05244863,CCOC(=O)N=C1SCCN1c1cccc(C(F)(F)F)c1.O=C1CCC(=O)N1Br>>CCOC(=O)N=c1sc(Br)cn1-c1cccc(C(F)(F)F)c1,,ClC(Cl)Cl,,,,test
US20060229336A1,N#CBr.Nc1ccc(C(=O)Nc2ccccc2N)cc1>>Nc1nc2ccccc2[nH]1,,CO,,,,test
US20080188473A1,CCOC(=O)c1cc2cc(-c3ccc(OC(C)C)cc3)ccc2[nH]1.O=C1CCC(=O)N1Br>>CCOC(=O)c1[nH]c2ccc(-c3ccc(OC(C)C)cc3)cc2c1Br,,CC(C)=O,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US06610692B1,CCOC(=O)Cn1c(C)cc([C@H]2CN(Cc3ccccc3)C[C@H]2c2ccccc2)cc1=O>>CCOC(=O)Cn1c(C)cc([C@H]2CNC[C@H]2c2ccccc2)cc1=O,[Pd],CCO,,CC(=O)O,,test
US20040157885A1,CC(C)c1ccc(C=CC(=O)N2CCCC(c3cccc(OC(C)(C)C(=O)OCc4ccccc4)c3)C2)cc1>>CC(C)c1ccc(CCC(=O)N2CCCC(c3cccc(OC(C)(C)C(=O)O)c3)C2)cc1,[Pd],CO,,,,test
US20100168075A1,CC(C)(C)OC(=O)COc1ccc([C@@H]2[C@@H](SSc3ncccc3[N+](=O)[O-])C(=O)N2c2ccc(F)cc2)cc1.O=C(CBr)c1ccc(Cl)cc1>>O=C(O)COc1ccc([C@@H]2[C@@H](SCC(=O)c3ccc(Cl)cc3)C(=O)N2c2ccc(F)cc2)cc1,,CC(C)=O,O,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150239900A1,N=CN.Nc1cc(Cl)c(C(F)(F)F)cc1C(=O)O>>Oc1ncnc2cc(Cl)c(C(F)(F)F)cc12,,CCOCCO,,CC(=O)O,,test
US20080319057A1,CC(C)(C)OC(=O)NCCc1cccc(O)c1.Fc1cccc(CCl)c1>>CC(C)(C)OC(=O)NCCc1cccc(OCc2cccc(F)c2)c1,,CN(C)C=O,,[I-].[K+],,test
US20080113882A1,CCO[Si](CCCN=C=O)(OCC)OCC.CN(CC(O)CN(C)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>CCO[Si](CCCNC(=O)OC(CN(C)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)CN(C)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)(OCC)OCC,,CCC(C)=O,,,,test
US20070010511A1,COCCCOc1cc(COC2CN(C(=O)OCc3ccccc3)CCC2c2ccc(OCCCOCc3ccccc3OC)cc2)ccc1C(=O)Cl.N>>COCCCOc1cc(COC2CN(C(=O)OCc3ccccc3)CCC2c2ccc(OCCCOCc3ccccc3OC)cc2)ccc1C(N)=O,,Cc1ccccc1,,,,test
US09242978B2,CC(C)(C)OC(=O)N1CC[C@H](C[C@@H](C(=O)Nc2ncc(F)s2)c2ccc(S(=O)(=O)C3CC3)cc2)C1>>O=C(Nc1ncc(F)s1)[C@H](C[C@H]1CCNC1)c1ccc(S(=O)(=O)C2CC2)cc1,,Cl,,,,test
US20050203081A1,CC(C)(C)OC(=O)CBr.COC(=O)c1sc2ncc([N+](=O)[O-])cc2c1O>>COC(=O)c1sc2ncc([N+](=O)[O-])cc2c1OCC(=O)OC(C)(C)C,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20020099068A1,BrBr.Brc1ccc2c(c1)[nH]c1cnccc12.ClC(Cl)Cl>>Brc1ccc2c3ccncc3n(Br)c2c1.Cl,,C1CCOC1,,,,test
US20060177943A1,COC(=O)N(CCOCCOCCOCCOCCOc1ccc(OCCOCCOCCOCCOCCOCC(=O)OC(C)(C)C)cc1)C1c2ccccc2-c2ccccc21>>COC(=O)N(CCOCCOCCOCCOCCOc1ccc(OCCOCCOCCOCCOCCOCC(=O)O)cc1)C1c2ccccc2-c2ccccc21,,Cc1ccccc1,,,,test
US20120115850A1,NCc1cccc(Br)c1.O=[N+]([O-])c1ccc(F)cc1F>>O=[N+]([O-])c1ccc(F)cc1NCc1cccc(Br)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20040102508A1,CCOc1c(C(=O)O)c(C(=O)O)c(OCC)c2ccccc12.Nc1ccc(CS(N)(=O)=O)cc1>>CCOc1c2c(c(OCC)c3ccccc13)C(=O)N(c1ccc(CS(N)(=O)=O)cc1)C2=O,,CC(=O)O,,O,,test
US20130085127A1,Cn1nccc1C(O)c1ccc(Cl)cc1.OC1CCNCC1>>Cn1nccc1C(OC1CCNCC1)c1ccc(Cl)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100069381A1,NNC(=O)c1ccc2occc2c1.S=C=S>>Sc1nnc(-c2ccc3occc3c2)o1,,CCO,,[K+].[OH-],,test
US20110313196A1,C=CC(N)=O.CCc1cc(Br)ccc1Cl>>CCc1cc(/C=C/C(N)=O)ccc1Cl,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US07678831B2,CCOC(=O)[C@H](CCc1ccccc1)Oc1ccc(-c2ccco2)cc1>>O=C(O)[C@H](CCc1ccccc1)Oc1ccc(-c2ccco2)cc1,,CCO,,O,[K+].[OH-],test
US04645779,C#CC(O)(c1ccc(OCCCN(CCC)CCC)cc1)c1ccc(Cl)cc1Cl>>CCCN(CCC)CCCOc1ccc(C(O)(CC)c2ccc(Cl)cc2Cl)cc1,[Pd],c1ccccc1,,[H][H],,test
US20100016287A1,CC(=O)N1CCc2ccc([N+](=O)[O-])cc2CC1>>CC(=O)N1CCc2ccc(N)cc2CC1,,CCO,,,,test
US20050026931A1,CC(C)(C)OC(=O)N1CCNCC1.CCS(=O)(=O)c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1F>>CCS(=O)(=O)c1ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c(Cl)c1N1CCNCC1,,CN1CCCC1=O,,[Cl-].[NH4+],,test
US20110046171A1,CCNC(=NS(=O)(=O)c1ccc(OC)cc1)N1N=CCC1c1ccccc1>>CCNC(=NS(=O)(=O)c1ccc(O)cc1)N1N=CCC1c1ccccc1,,ClCCl,,BrB(Br)Br,,test
US20100203007A1,COC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO.Cc1ccccc1S(=O)(=O)Cl>>COC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20060004197A1,CC(=O)Nc1cc(F)c(C(=O)O)cc1[N+](=O)[O-].CO>>COC(=O)c1cc([N+](=O)[O-])c(N)cc1F,,CO,,Cl,O=C([O-])O.[Na+],test
US04469703,CC(O)[N+](=O)[O-].O=Cc1ccc([N+](=O)[O-])cc1>>O=[N+]([O-])c1ccc(C(O)C(CO)[N+](=O)[O-])cc1,,CCN(CC)CC,CO,CC(=O)O,Cl,test
US20070099990A1,Cc1cc2c(c3occ(-c4ccc(C(C)C)cc4)c13)CCCC2>>Cc1cc2c(c3c1C(c1ccc(C(C)C)cc1)CO3)CCCC2,,CO,,,,test
US04813998,CI.COC(=O)c1cncn1[C@H]1C[C@H](C)Oc2ccccc21>>COC(=O)C1=CN(C)C[NH+]1[C@H]1C[C@H](C)Oc2ccccc21.[I-],,ClCCl,,,,test
US20090099195A1,CC(=O)Cl.CC(C)N1Cc2c(NCc3cc4ccccc4cn3)nc(N3CCN(C(=O)OC(C)(C)C)[C@@H](C)C3)nc2C1=O.CCN(C(C)C)C(C)C>>CC(=O)N(Cc1cc2ccccc2cn1)c1nc(N2CCN(C(C)=O)[C@@H](C)C2)nc2c1CN(C(C)C)C2=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070124152A1,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN2C(=O)c3ccccc3C2=O)c1=O.NCCCn1ccnc1>>O=C(NCCCn1ccnc1)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN2C(=O)c3ccccc3C2=O)c1=O,,CCO,,,,test
US20100240678A1,CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(C(=O)C(C)C)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)OCC>>CC(C)C(=O)c1cc(OCCCCCCc2cccc(OCCCC(=O)O)c2CCC(=O)O)cc(-c2ccc3c(c2)OCO3)c1,,CCO,O,Cl,[Na+].[OH-],test
US20120232056A1,COC(=O)c1ccc2nc(C3Cc4ccccc4C3)c(N(C)C3CC3)nc2c1.[Li]O>>CN(c1nc2cc(C(=O)O)ccc2nc1-c1cc2ccccc2o1)C1CC1,,CO,ClC(Cl)Cl,O,O,test
US20030149056A1,CC=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)c(C#N)cnc2cc1OCC.CNC>>CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)CC(C)N(C)C,,C1CCOC1,,,,test
US04622395,CC(=O)N1c2ccc(NS(C)(=O)=O)cc2Oc2cc(NS(C)(=O)=O)ccc21>>CS(=O)(=O)Nc1ccc2c(c1)Oc1cc(NS(C)(=O)=O)ccc1N2,,O,,Cl,[Na+].[OH-],test
US20070010511A1,CN(C)c1ccccc1.COC(C)(C)C.COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CCC3c3ccc(O)cc3)cc21.Cc1ccccc1.O=C(Cl)Cl>>COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CCC3c3ccc(OC(=O)N4CCC(c5ccccc5)C4)cc3)cc21,,COC(C)(C)C,,,,test
US20130338142A1,COc1cc([N+](=O)[O-])ccc1OC1CCC1>>COc1cc(N)ccc1OC1CCC1,[Pd],CO,,,,test
US20140163024A1,COC(=O)c1ccc(S(=O)(=O)N(CC(C)C)c2ccc(F)cc2)cc1>>CC(C)CN(c1ccc(F)cc1)S(=O)(=O)c1ccc(C(=O)O)cc1,,CO,,[Na+].[OH-],,test
US05593993,COC(=O)C(N)Cc1ccccc1.S=C(Nc1nccs1)n1ccnc1>>COC(=O)C(Cc1ccccc1)NC(=S)Nc1nccs1,,CN(C)C=O,,Cl,,test
US05063247,CC(C)c1cccc(C(C)C)c1N.CCCCCCCCCc1ccc(C(=O)O)cc1.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>CCCCCCCCCc1ccc(NC(=O)Nc2c(C(C)C)cccc2C(C)C)cc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20100152160A1,CN(C)C=O.N#CC1(Cc2ccc(F)cc2)CCN(C(=O)C2CNc3cc(Cl)ccc3O2)CC1>>N#CN1CC(C(=O)N2CCC(C#N)(Cc3ccc(F)cc3)CC2)Oc2ccc(Cl)cc21,,O,,O=C([O-])[O-].[K+].[K+],,test
US20060293352A1,COc1ccc(F)cc1Oc1ccc([N+](=O)[O-])cc1Cl>>COc1ccc(F)cc1Oc1ccc(N)cc1Cl,[Fe],CC(=O)O,,,,test
US04053606,C=Cc1cnc(C)c(O)c1C(C)=O.CC[Mg]Br>>C=Cc1cnc(C)c(O)c1C(C)(O)CC,,C1CCOC1,,,,test
US04803280,C=CC(=O)OCC.COC(=O)NNC(=S)Cc1ccc(C)cc1>>CCOC(=O)CCSC(Cc1ccc(C)cc1)=NNC(=O)OC,,c1ccccc1,,CCN(CC)CC,,test
US20110015196A1,C=C(C)[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(C)=O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CC1(C)[C@@H](N)C[C@H]1C(=O)N1CCCCC1>>C=C(C)[C@@H]1CC[C@]2(C(=O)N[C@H]3C[C@@H](C(=O)N4CCCCC4)C3(C)C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(C)=O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,ClCCl,,CCN(CC)CC,,test
US20100292143A1,CCOC(=O)Cc1nc(NC(=O)c2cc(CC(C)C)cn2Cc2ccc(F)cc2F)sc1Cl>>CC(C)Cc1cc(C(=O)Nc2nc(CC(=O)O)c(Cl)s2)n(Cc2ccc(F)cc2F)c1,,C1CCOC1,O,CO,[Li+].[OH-],test
US20070259869A1,COC(=O)c1ccc(Sc2nc(Nc3cc(C)n[nH]3)cc(N3CCC3)n2)cc1>>Cc1cc(Nc2cc(N3CCC3)nc(Sc3ccc(C(=O)O)cc3)n2)[nH]n1,,CO,,C1CCOC1,[Na+].[OH-],test
US20080009507A1,COc1nccc2nc(-c3ccc(C(C)(C)N)cc3)c(-c3cccs3)cc12>>CC(C)(N)c1ccc(-c2nc3cc[nH]c(=O)c3cc2-c2cccs2)cc1,,C1CCOC1,,Cl,,test
US20150252038A1,CC(C)(C)[Si](C)(C)O[C@@H]1CCC(=O)N(Cc2ccc(F)cc2Cl)C1.O=S(=O)(NF)c1ccccc1>>CC(C)(C)[Si](C)(C)O[C@@H]1CC(F)C(=O)N(Cc2ccc(F)cc2Cl)C1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US04895840,CC(C)N(CCS(=O)(=O)c1ccccc1)C(=O)Cl.CCN(CC)CCNCCN(CC)CC>>CCN(CC)CCN(CCN(CC)CC)C(=O)N(CCS(=O)(=O)c1ccccc1)C(C)C,,C1CCOC1,CCOCC,CCN(CC)CC,,test
US20110269780A1,CCOC(=O)C[C@@H](Nc1nc(C2CC2)ncc1[N+](=O)[O-])c1ccccc1>>CCOC(=O)C[C@@H](Nc1nc(C2CC2)ncc1N)c1ccccc1,[Pd],CCOC(C)=O,,,,test
US03947406,CC1CC(C)(C)CC(N)(OO)C1.CCCC=O>>CC1CC(=O)CC(C)(C)C1.CCCC=O,O=S(=O)(O)O,,,O=S(=O)([O-])[O-].[Mg+2],,test
US20120184531A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C1CC(O)CCN1>>COC(=O)C1CC(O)CCN1C(=O)OC(C)(C)C,,CO,,CCN(CC)CC,,test
US20070213392A1,CCOC(=O)c1cc2ccc(C(=O)O)cc2s1>>CCOC(=O)c1cc2ccc(CO)cc2s1,,C1CCOC1,,,,test
US20050113397A1,CCC(N)=S.CCOC(=O)CC(=O)CCl>>CCOC(=O)Cc1csc(CC)n1,,CCO,,,,test
US05100902,COc1cc2c(cc1OC)C(C(=O)O)=C2.Fc1ccc2c(C3CCNCC3)noc2c1>>COc1cc2c(cc1OC)C(C(=O)N1CCC(c3noc4cc(F)ccc34)CC1)=C2,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20130079306A1,COc1cc(Cl)ccc1-c1nc(C)c(N)s1.COc1ccc(C=CC(=O)O)cc1>>COc1ccc(C=CC(=O)Nc2sc(-c3ccc(Cl)cc3OC)nc2C)cc1,,c1ccncc1,,O=S(Cl)Cl,,test
US20130143870A1,CC(=O)OC(C)=O.NC1CN(C(=O)OCc2ccccc2)CC1O>>CC(=O)NC1CN(C(=O)OCc2ccccc2)CC1O,,ClCCl,,CCOCC,,test
US06150373,CN1C(=O)N(c2c(Cl)cccc2Cl)Cc2cnc(S(C)(=O)=O)nc21.Nc1ccc(F)cc1>>CN1C(=O)N(c2c(Cl)cccc2Cl)Cc2cnc(Nc3ccc(F)cc3)nc21,,CCOC(C)=O,,Cl,,test
US20080188528A1,COC(=O)c1cccn(C(C)c2ccccc2)c1=O>>CC(c1ccccc1)n1cccc(C(=O)O)c1=O,,C1CCOC1,CO,[Na+].[OH-],,test
US20120041093A1,CC1(C)CC(O)CC(C)(C)N1N=Nc1ccccc1.O=C(Cl)c1ccccc1>>CC1(C)CC(OC(=O)c2ccccc2)CC(C)(C)N1N=Nc1ccccc1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20030109700A1,CC(C)OB(OC(C)C)OC(C)C.FC(F)(F)c1ccc(Br)cc1>>OB(O)c1ccc(C(F)(F)F)cc1,,C1CCOC1,,[Li]CCCC,,test
US20040147580A1,BrBr.CC(C)(C)OC(=O)N1CCOc2cccnc21>>CC(C)(C)OC(=O)N1CCOc2cc(Br)cnc21,,CO,,,,test
US20160039783A1,CCI.CCOC(=O)C(O)c1c(C)sc(-c2ccncc2)c1C1=CCC(C)(C)CC1>>CCOC(=O)C(OCC)c1c(C)sc(-c2ccncc2)c1C1=CCC(C)(C)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20070004775A1,COC(=O)[C@H](Cc1ccc2nc(-c3c(Cl)cccc3Cl)ccc2c1)NC(=O)c1c(Cl)cncc1Cl>>O=C(N[C@@H](Cc1ccc2nc(-c3c(Cl)cccc3Cl)ccc2c1)C(=O)O)c1c(Cl)cncc1Cl,,C1CCOC1,,[Na+].[OH-],,test
US20060270693A1,CC(C)(C)OC(=O)NCCBr.Oc1ccc(F)cc1>>CC(C)(C)OC(=O)NCCOc1ccc(F)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040044201A1,CC1CCC2OC2CN1C(=O)OCc1ccccc1.[N-]=[N+]=[N-]>>CC1CCC(N=[N+]=[N-])C(O)CN1C(=O)OCc1ccccc1,,CO,O,[Cl-].[NH4+],,test
US20070254866A1,CCOC(=O)c1c(C)n(C2CC2)c2c(OC)c(F)c(F)c([N+](=O)[O-])c2c1=O>>CCOC(=O)c1c(C)n(C2CC2)c2c(OC)c(F)c(F)c(N)c2c1=O,[Fe],CC(=O)O,,,,test
US20050137243A1,O=C(Cc1ccc(OCc2ccccc2)cc1)Nc1cccc2c1cnn2CCN1CCCC1>>O=C(Cc1ccc(O)cc1)Nc1cccc2c1cnn2CCN1CCCC1,[Pd],CCO,,,,test
US04268678,CCC(=O)C(CCCCCCOc1ccc(Br)cc1)C(=O)CC.NO>>CCc1noc(CC)c1CCCCCCOc1ccc(Br)cc1,,c1ccncc1,,Cl,,test
US20140024666A1,CCOC(=O)CN=C=O.O=C1CC(=O)N(Cc2ccccc2)C(=O)N1>>CCOC(=O)CNC(=O)c1c(O)[nH]c(=O)n(Cc2ccccc2)c1=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110281865A1,CC(C)(O)c1ccc(Br)cc1F.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(C)(O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1F,,C1COCCO1,,ClCCl,CC(=O)[O-].[K+],test
US20050004162A1,CCOC(=O)Cc1coc2c1ccc1ccccc12>>OCCc1coc2c1ccc1ccccc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05298403,CCC1(c2ccccc2)C(=O)N(CCCCC(=O)OC)C(=O)N=C1O.CN(C)c1ccccn1.O.O=C1CCC(=O)O1>>CCC1(c2ccccc2)C(=O)NC(=O)N(CCCCC(=O)NCCOC(=O)CCC(=O)O)C1=O,,ClC(Cl)Cl,ClCCl,,,test
US03940394,CCOC(=O)CSc1nc(Cl)cc(Cl)n1.Nc1ccc(-c2ccccc2)cc1>>CCOC(=O)CSc1nc(Cl)cc(Nc2ccc(-c3ccccc3)cc2)n1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20120157439A1,N.Nc1c(F)ccc(NS(=O)(=O)c2ccccc2)c1F.O=C(Cl)c1csc2c(Cl)ncnc12>>Nc1ncnc2c(C(=O)Nc3c(F)ccc(NS(=O)(=O)c4ccccc4)c3F)csc12,,C1COCCO1,ClC(Cl)Cl,,,test
US20130079324A1,Cn1cc(Nc2nc(N[C@@H]3C[C@@H](NC(=O)OC(C)(C)C)C3)c3ccn(COCC[Si](C)(C)C)c3n2)cn1>>Cn1cc(Nc2nc(N[C@H]3C[C@H](N)C3)c3ccn(COCC[Si](C)(C)C)c3n2)cn1,,ClCCl,,C1COCCO1,Cl,test
US20110207702A1,O=Cc1ccc(Sc2ccc(Cl)cc2)cc1Br>>OCc1ccc(Sc2ccc(Cl)cc2)cc1Br,,CO,,[BH4-].[Na+],,test
US05612477,CCOC(=O)C(=O)CC(C)=O.NNCCc1ccccc1>>CCOC(=O)c1cc(C)n(CCc2ccccc2)n1,,ClCCl,,,,test
US20100210610A1,COC(=O)Cc1c(C)[nH]c2nc(Cl)ccc12.CS(=O)(=O)c1ccc(CBr)c(C(F)(F)F)c1>>Cc1c(CC(=O)O)c2ccc(Cl)nc2n1Cc1ccc(S(C)(=O)=O)cc1C(F)(F)F,,CN(C)C=O,,[H-].[Na+],,test
US20090104464A1,CC(C)(Br)C(=O)c1ccc(C(CC(=O)[O-])c2ccccc2)cc1.[OH-]>>CC(C)(O)C(=O)c1ccc(C(CC(=O)O)c2ccccc2)cc1,,COCCOC,,O,,test
US20140088094A1,O=[N+]([O-])c1ccc2c(c1)N(S(=O)(=O)c1ccc(F)cc1)C[C@H](CO)O2>>Nc1ccc2c(c1)N(S(=O)(=O)c1ccc(F)cc1)C[C@H](CO)O2,,C1CCOC1,CO,O=C[O-].[NH4+],,test
US20060004000A1,Brc1cncc2ccccc12.O=[N+]([O-])O>>O=[N+]([O-])c1cccc2c(Br)cncc12,,O,O=S(=O)(O)O,,,test
US20050288314A1,N#Cc1c(F)cccc1F.OCC1CC2CCC1C2>>N#Cc1cc(OCC2CC3CCC2C3)ccc1F,,CN(C)C=O,,[H-].[Na+],,test
US20100204196A1,COc1cc2c(cc1Nc1nc(Nc3ccccc3C(N)=O)c3ccn(S(=O)(=O)c4ccc(C)cc4)c3n1)N(C(=O)CN(C)C)CC2>>COc1cc2c(cc1Nc1nc(Nc3ccccc3C(N)=O)c3ccnc-3[nH]1)N(C(=O)CN(C)C)CC2,,C1COCCO1,CCOC(C)=O,[K+].[OH-],,test
US20020058662A1,CCNCC.COc1ccc(C(=O)Cl)cc1OCc1ccccc1>>CCN(CC)C(=O)c1ccc(OC)c(OCc2ccccc2)c1,,ClCCl,,,,test
US20110076292A1,COc1cc(Cl)c(-c2nc(-c3nc(C)nn3C(C)C)c[nH]2)cn1.O=C1OCCO1>>COc1cc(Cl)c(-c2nc(-c3nc(C)nn3C(C)C)cn2CCO)cn1,,Cc1ccccc1,,,,test
US20100184770A1,COCCCC(=O)NCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O.Cl>>COCCCC(=O)NCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O.Cl,,CO,,,,test
US20070254906A1,COc1cc2c(cc1OC)[C@@H]1c3ccccc3CN[C@H]1CC2.Cl>>Cl.Oc1cc2c(cc1O)[C@@H]1c3ccccc3CN[C@H]1CC2,,Br,,,,test
US20140248646A1,C=O.CCN(CC)c1ccc(C(=O)c2ccccn2)cc1.COc1ccc(N)cc1.Cl>>CCN(CC)c1ccc(-c2c3cccc[n+]3cn2-c2ccc(OC)cc2)cc1.[Cl-],,CCO,,,,test
US04163048,CCCCN.Cc1nsc(Cl)n1>>CCCCNc1nc(C)ns1,,CCO,,,,test
US20060079533A1,CC(C)(C)OC(=O)N1CCC(c2ccc(COC(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)C(OCc2ccc3ccccc3c2)C1>>OCc1ccc(C2CCNCC2OCc2ccc3ccccc3c2)cc1,,CO,,Cl,,test
US05610144,COC(=O)Cc1cccc(NC(=O)NCC(=O)N2C(c3ccccc3)CCC2c2ccccc2OC)c1>>COc1ccccc1C1CCC(c2ccccc2)N1C(=O)CNC(=O)Nc1cccc(CC(=O)O)c1,,CO,,,,test
US20150203468A1,COC(=O)[C@H]1[C@H](c2ccc(Br)cc2)[C@H]1c1ccccc1.ClC(Cl)(Cl)Cl>>COC(=O)[C@@]1(Cl)[C@H](c2ccc(Br)cc2)[C@H]1c1ccccc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20070249620A1,CC(C)(C)OC(=O)N1CCN(c2ccc(N)cc2)CC1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N1CCN(c2ccc(NC(=O)Oc3ccc([N+](=O)[O-])cc3)cc2)CC1,,C1CCOC1,Cl,c1ccncc1,,test
US20040167160A1,CCOC(=O)C=C(C)c1cc2cccc(-c3cc(C(C)C)cc(C(C)C)c3OCC(F)F)c2o1>>CC(=CC(=O)O)c1cc2cccc(-c3cc(C(C)C)cc(C(C)C)c3OCC(F)F)c2o1,,CO,,C1CCOC1,[Li+].[OH-],test
US04065288,CC(C)NP(=O)(O)CCCl.CC[O-]>>CC(C)[NH-].CCOP(=O)(O)CCCl,,c1ccccc1,,[Cl-].[Na+],,test
US20140005213A1,CC(C)(C)OC(=O)N[C@H]1CCNC1.O=S(=O)(OC(c1ccc(Cl)nc1)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N[C@H]1CCN(C(c2ccc(Cl)nc2)C(F)(F)F)C1,,C1CCOC1,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US20100029710A1,CCc1nc2c(C)cc(Cc3ccccc3)nc2n1[C@H]1CCc2cc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)ccc21>>CCc1nc2c(C)cc(Cc3ccccc3)nc2n1[C@H]1CCc2cc(-c3ccccc3-c3nnn[nH]3)ccc21,,CC(C)=O,,Cl,O,test
US06541486B1,CCOC(=N)CC(=N)OCC.Nc1ccc(Cl)cc1N.Nc1cccc([N+](=O)[O-])c1N>>O=[N+]([O-])c1cccc2[nH]c(Cc3nc4cc(Cl)ccc4[nH]3)nc12,,CC(=O)O,,Cl,Cl,test
US20020103229A1,NC(=O)c1ccc2c(c1)c(-c1cccc(NC(=O)CCC3CCCNC3)c1)nn2C1CCCCO1>>NC(=O)c1ccc2[nH]nc(-c3cccc(NC(=O)CCC4CCCNC4)c3)c2c1,,Cc1ccccc1,,,,test
US05789440,Cc1ccc(S)c(C(C)C)c1.O=C1OC(CCc2ccccc2)(c2ccccc2)CC(O)=C1Br>>Cc1ccc(SC2=C(O)CC(CCc3ccccc3)(c3ccccc3)OC2=O)c(C(C)C)c1,,ClCCl,,C1CCNCC1,,test
US20090186907A1,CCC(C)Cn1c(-c2c(F)cc(OC)cc2F)c(Cl)nc(Cl)c1=O.c1cn[nH]c1>>CCC(C)Cn1c(-c2c(F)cc(OC)cc2F)c(Cl)nc(-n2cccn2)c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050245602A1,C=CC#N.O=S(=O)(Oc1ccc(C2=C(c3ccccc3)CCCc3ccccc32)cc1)C(F)(F)F>>N#CC=Cc1ccc(C2=C(c3ccccc3)CCCc3ccccc32)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,CCN(CC)CC,,test
US06806230B1,CC(C(=O)CNC(c1cncnc1C(=O)O)C(C)C)c1ccc(Cl)cc1.CO>>COC(=O)c1ncncc1C(NCC(=O)C(C)c1ccc(Cl)cc1)C(C)C,O=S(=O)(O)O,O,,,,test
US20030045558A1,CCOC(=O)C(C)(C)Oc1ccc(OCCc2nc(-c3ccc(Br)cc3)oc2C)cc1.COc1ccc(B(O)O)cc1>>CCOC(=O)C(C)(C)Oc1ccc(OCCc2nc(-c3ccc(-c4ccc(OC)cc4)cc3)oc2C)cc1,,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US05665718,CN(C)C=O.CN1Cc2c(C(=O)O)ncn2-c2ccsc2C1=O.O=C(n1ccnc1)n1ccnc1>>CN1Cc2c(Cc3ccc4c(c3)C(=O)NC4=O)ncn2-c2ccsc2C1=O,,CN(C)C=O,,O,,test
US20100152168A1,CC(C)(C)OC(=O)Cn1c(=O)[nH]c2ccccc21.ClCCl.O=C(O)C(F)(F)F>>O=C(O)C(c1ccccc1)n1c(=O)[nH]c2ccccc21,,ClCCl,,,,test
US20100331293A1,CC(C)I.Cc1c(N2CCNC(=O)C2)nc2cc(F)cc(F)c2c1Br>>Cc1c(N2CCN(C(C)C)C(=O)C2)nc2cc(F)cc(F)c2c1Br,,C1CCOC1,,[H-].[Na+],,test
US20110207699A1,CC1(C)OB(c2ccc(F)c(F)c2)OC1(C)C.O=[N+]([O-])c1cc(F)c(N2CC=C(OS(=O)(=O)C(F)(F)F)CC2)c(F)c1>>O=[N+]([O-])c1cc(F)c(N2CC=C(c3ccc(F)c(F)c3)CC2)c(F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US20080096877A1,CN(c1cccc2cc(C(N)=O)[nH]c12)S(=O)(=O)c1ccccc1C(F)(F)F.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CN(c1cccc2cc(C(N)=S)[nH]c12)S(=O)(=O)c1ccccc1C(F)(F)F,,C1CCOC1,,,,test
US04349684,COC(=O)CCCCCCCn1cc(-c2ccccc2)n(-c2ccc(Cl)cc2)c1=O>>O=C(O)CCCCCCCn1cc(-c2ccccc2)n(-c2ccc(Cl)cc2)c1=O,,CO,,[Na+].[OH-],,test
US20160152543A1,COC(=O)C(OC(C)(C)C)c1c(C)ccc(C2CC2)c1-c1ccc([N+](=O)[O-])cc1>>COC(=O)C(OC(C)(C)C)c1c(C)ccc(C2CC2)c1-c1ccc(N)cc1,[Pd],CO,,,,test
US20070167433A1,CC(O)CCO[Si](C(C)C)(C(C)C)C(C)C.CS(=O)(=O)Cl>>CC(C)[Si](OCC[C@H](C)OS(C)(=O)=O)(C(C)C)C(C)C,,C1CCOC1,,CCN(CC)CC,,test
US20100216788A1,O=[N+]([O-])c1ccc(F)c(Cl)c1.Oc1cccc(-c2cncs2)c1>>O=[N+]([O-])c1ccc(Oc2cccc(-c3cncs3)c2)c(Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04201790,CC(C)N.Cc1cc(C)c(C(=O)c2ccccc2)c(OCC2CO2)c1C>>Cc1cc(C)c(C(=O)c2ccccc2)c(OCC(O)CNC(C)C)c1C,,CO,,,,test
US04629797,COC(=O)CNC(=O)CC(=O)CBr>>COC(=O)CNC(=O)CC(O)CBr,,COCCOC,,[BH4-].[Na+],,test
US20110275611A1,CNc1nc(-c2cc(F)c(C#N)c(SC)c2)cc(N2CCOC[C@H]2C)n1.NN>>CNc1nc(-c2cc(SC)c3c(N)n[nH]c3c2)cc(N2CCOC[C@H]2C)n1,,CCO,,CCN(C(C)C)C(C)C,,test
US20120263670A1,CN1Cc2c(Cl)cc(Cl)cc2C(c2cccc(S(=O)(=O)Cl)c2)C1.[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN>>CN1Cc2c(Cl)cc(Cl)cc2C(c2cccc(S(=O)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])c2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20080132563A1,CCc1ccc(C(O)c2ccccc2OCc2ccccc2)cc1>>CCc1ccc(Cc2ccccc2O)cc1,[Pd],CO,,Cl,,test
US20150141243A1,Cc1cc(Cl)cc(C(=O)N=S(C)CC[Si](C)(C)C)c1N.O=C(Cl)c1cc(C(F)(F)F)nn1-c1ncccc1Cl>>Cc1cc(Cl)cc(C(=O)N=S(C)CC[Si](C)(C)C)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US04822786,ClC(c1ccccc1)c1ccccc1.O=c1cc(CO)n(O)cc1OC(c1ccccc1)c1ccccc1>>O=c1cc(CO)n(OC(c2ccccc2)c2ccccc2)cc1OC(c1ccccc1)c1ccccc1,,CS(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US06211234B1,CCOC(=O)CCC(Cl)c1ccccc1.COC(=O)c1ccc(OCc2ccccc2)cc1O>>CCOC(=O)CCC(Oc1cc(OCc2ccccc2)ccc1C(=O)OC)c1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20140046069A1,COC(=O)c1cnc(N2CCC(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1C(F)(F)F>>O=C(O)c1cnc(N2CCC(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1C(F)(F)F,,CCO,,O,[Na+].[OH-],test
US20010000345A1,CCN=C(S)N(C(=O)OCc1ccccc1)C(=O)OCc1ccccc1.Cc1c(N)ccc2c1ncn2C(=O)OC(C)(C)C>>Cc1c(NC(=NC(=O)OCc2ccccc2)NC(=O)OCc2ccccc2)ccc2c1ncn2C(=O)OC(C)(C)C,,C1CCOC1,,CCOC(C)=O,,test
US20110306590A1,Cc1ccc2[nH]c(C3CN(C(=O)OC(C)(C)C)C3)nc2c1>>Cc1ccc2[nH]c(C3CNC3)nc2c1,,CO,,Cl,,test
US20070299085A1,Cc1cc(C(=O)CC(=O)C(F)(F)F)ccc1[N+](=O)[O-].NNCC(F)(F)F>>Cc1cc(-c2cc(C(F)(F)F)nn2CC(F)(F)F)ccc1[N+](=O)[O-],,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20070299067A1,COc1cc2cc[nH]c(=O)c2cc1OC.O=P(Br)(Br)Br>>COc1cc2ccnc(Br)c2cc1OC,,CC#N,,CCOC(C)=O,,test
US04146715,Nc1nc2c(ncn2COCCOC(=O)c2ccccc2)c(=O)[nH]1>>Nc1nc2c(ncn2COCCO)c(=O)[nH]1,,CO,,N,,test
US20110237596A1,Clc1ccc(Oc2cccc(CN3CCNCC3)c2)cc1.Nc1nc2ccccc2o1.O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O>>O=C(Nc1nc2ccccc2o1)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,Cl,test
US20080234261A1,CC(=O)c1cccc(O)c1.CCn1c(-c2nonc2N)nc2cnc(Br)cc21>>CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(C(C)=O)c3)cc21,I[Cu]I,CCOC(C)=O,Cc1ccccc1,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US20070149783A1,C=O.CC(=O)O.CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3cc(O)ccc3nc2-1.CNC>>CC(=O)O.CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(CN(C)C)c(O)ccc3nc2-1,,CC(=O)O,,CC(C)=O,,test
US20100184740A1,CCCCC([Sn])=C(CCCC)CCCC.COc1cc([N+](=O)[O-])ccc1-n1cccc(Br)c1=O>>C=Cc1cccn(-c2ccc([N+](=O)[O-])cc2OC)c1=O,,C1COCCO1,,,,test
US20040024010A1,CCOC(=O)CCc1c(C=O)[nH]c(C(=O)OCC)c1C.O=C1Cc2ccc(Cl)cc2N1>>Cc1c(C(=O)O)[nH]c(C=C2C(=O)Nc3cc(Cl)ccc32)c1CCC(=O)O,C1CCNCC1,CCO,,[K+].[OH-],,test
US20070225318A1,CN(C)c1ccncc1.Nc1ccc2cn[nH]c2c1.O=c1c2ccnn2c(=O)c2ccnn12>>CCCC(C)C.O=C(Nc1ccc2cn[nH]c2c1)c1cc[nH]n1,CN(C)c1ccncc1,ClC(Cl)Cl,,,,test
US20120015963A1,Cc1ccc(Nc2ncc3cnn(C[C@H]4CC[C@@H](NC(=O)OC(C)(C)C)CC4)c3n2)cc1S(N)(=O)=O>>Cc1ccc(Nc2ncc3cnn(C[C@@H]4CC[C@H](N)CC4)c3n2)cc1S(N)(=O)=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060160865A1,CCCNCCC.CN(C(=O)Oc1ccc(N)cn1)c1ccccc1.S=C(Oc1ccccn1)Oc1ccccn1>>CCCN(CCC)C(=S)Nc1ccc(OC(=O)N(C)c2ccccc2)nc1,,CN(C)C=O,,CCN(CC)CC,,test
US04246201,CI.Oc1ccc(SCCCNCCC(c2ccccc2)c2ccccc2)cc1>>CN(CCCSc1ccc(O)cc1)CCC(c1ccccc1)c1ccccc1,,CO,,,,test
US20040038964A1,BrBr.C[Si](C)(C)CCOCn1cc(-c2ccncc2)nc1-c1ccccc1>>C[Si](C)(C)CCOCn1c(-c2ccccc2)nc(-c2ccncc2)c1Br,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20050070563A1,BrCc1ccc(Br)cc1.CC(C)(C)OC(=O)N1CCC2(CCNC2=O)CC1>>CC(C)(C)OC(=O)N1CCC2(CC1)CCN(Cc1ccc(Br)cc1)C2=O,,CN(C)C=O,,O,[H-].[Na+],test
US20090270374A1,COC(CN)OC.COc1ccc([N+](=O)[O-])c(Cl)n1>>COc1ccc([N+](=O)[O-])c(NCC(OC)OC)n1,,CC#N,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20140252279A1,CCCCCCCCCC(CCCCCCC)c1csc2c(Br)csc12>>CCCCCCCCCC(CCCCCCC)c1csc2ccsc12,,CCOCC,,O,[Li]CCCC,test
US05872115,NCC1CCN(C(c2ccccc2)c2ccccc2)CC1.O=c1[nH]c2ccccc2c(=O)o1>>Nc1ccccc1C(=O)NCC1CCN(C(c2ccccc2)c2ccccc2)CC1,,ClCCl,,ClC(Cl)Cl,,test
US06136823,C#Cc1c(F)c(F)cc2c(=O)c(C(=O)O)cn(-c3cc(N)c(F)cc3F)c12.CN>>C#Cc1c(NC)c(F)cc2c(=O)c(C(=O)O)cn(-c3cc(N)c(F)cc3F)c12,,c1ccncc1,,,,test
US05134142,CCOC(=O)C(=O)CC(=O)c1ccc(NC=O)cc1.NNc1ccc(F)cc1>>CCOC(=O)c1cc(-c2ccc(N)cc2)n(-c2ccc(F)cc2)n1,,CC(=O)O,,Cl,,test
US06887881B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1(O)C2CN(Cc3ccccc3)CC1CN(Cc1ccccc1)C2>>CC(C)(C)OC(=O)N1CC2CN(Cc3ccccc3)CC(C1)C2(C)O,[Pd],CCO,,,,test
US20020120148A1,CC(C)(C)OC(=O)N(Cc1ccccc1)C1CCCc2cc(O)ccc2C1.O=C1CCC(=O)N1Cl>>CC(C)(C)OC(=O)N(Cc1ccccc1)C1CCCc2cc(O)c(Cl)cc2C1,,C1COCCO1,,,,test
US20120101134A1,CCOC(=O)CCc1cc(F)cc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)c1OC>>COc1c(CCC(=O)O)cc(F)cc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1,,C1CCOC1,O,Cl,[Na+].[OH-],test
US06143779,CC(=O)Cl.COc1ccc(C=C2Oc3cc(O)ccc3C2=O)cc1C>>COc1ccc(C=C2Oc3cc(OC(C)=O)ccc3C2=O)cc1C,,c1ccncc1,,CCOC(C)=O,,test
US20060004017A1,COc1ccc2cc(F)cnc2c1>>Oc1ccc2cc(F)cnc2c1,,ClCCl,,BrB(Br)Br,CO,test
US05112851,CI.Cc1ccccc1C(C)(O)c1ccccc1>>COC(C)(c1ccccc1)c1ccccc1C,,C1CCOC1,,Cl,[H-].[Na+],test
US20060281731A1,CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@H](N)C(=O)N(Cc2cccnc2)C1.COC1C(=O)O[C@H]2C1OC(C)(C)O[C@@H]2/C=C/C(C)(C)C>>CO[C@@H](C(=O)N[C@H]1CC[C@@H](O[Si](C)(C)C(C)(C)C)CN(Cc2cccnc2)C1=O)[C@@H]1OC(C)(C)O[C@H](/C=C/C(C)(C)C)[C@H]1O,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US04604397,CCCNCCC(=O)OC.COc1ccc2c(c1)CC(=O)CS2>>CCCN1CCC(=O)C2=C1CSc1ccc(OC)cc12,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US20140171422A1,CI.CSc1ncc2c(n1)N1C[C@@H](O)C[C@H]1CN(c1cccc3c(=O)n(C)cnc13)C2=O>>CO[C@H]1C[C@H]2CN(c3cccc4c(=O)n(C)cnc34)C(=O)c3cnc(SC)nc3N2C1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],[Cl-].[NH4+],test
US20050130954A1,CC(C)(C)OC(=O)N1CCN(c2ncncc2OCc2ccccc2)CC1>>CC(C)(C)OC(=O)N1CCN(c2ncncc2O)CC1,[Pd],CO,,,,test
US20020193385A1,CCCC[Sn](CCCC)(CCCC)c1ccccn1.Nc1ccc(F)c(Br)c1F>>Nc1ccc(F)c(-c2ccccn2)c1F,[Cu]I,C1CCOC1,,[Cl-].[Li+],,test
US20040162331A1,CCOC(=O)CBr.Oc1cccc(I)c1>>COC(=O)COc1cccc(I)c1,,CC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150329533A1,CCOC(=O)/C(O)=C/C(=O)c1ccccc1.NN>>CCOC(=O)c1cc(-c2ccccc2)[nH]n1,,CCO,,Cl,O,test
US05137913,Brc1cccc(I)c1.Sc1ccc2ccccc2c1>>Brc1cccc(Sc2ccc3ccccc3c2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020028835A1,CC(C)(C)[Si](C)(C)OC1CN(C(c2ccccc2)c2ccccc2)C1.O=[N+]([O-])c1ccc(F)cc1>>O=[N+]([O-])c1ccc(N2CC(O)C2)cc1,[Pd],CO,c1ccncc1,O=C[O-].[NH4+],,test
US20120184516A1,N#CCC#N.N=C(N)c1cc(-c2ccon2)n(Cc2ccccc2F)n1>>Nc1cc(N)nc(-c2cc(-c3ccon3)n(Cc3ccccc3F)n2)n1,,CCO,,,,test
US20130274479A1,O=C(Cl)c1ccccc1.O=C(NO)OCC1c2ccccc2-c2ccccc21>>O=C(NOC(=O)c1ccccc1)OCC1c2ccccc2-c2ccccc21,,CCOC(C)=O,,CCN(CC)CC,O,test
US20040214106A1,N#Cc1ccc(N)cc1.O=NOS(=O)(=O)O.Oc1ccccc1Br>>N#Cc1ccc(N=Nc2ccc(O)c(Br)c2)cc1,,CO,O,Cl,[Na+].[OH-],test
US20100137386A1,CC(C)(C)OC(=O)Nc1ccc(N=C=S)cc1.N#CC(N)C(N)=O>>CC(C)(C)OC(=O)Nc1ccc(Nc2nc(C(N)=O)c(N)s2)cc1,,CCOC(C)=O,,,,test
US20100291026A1,COC(=O)NC1CN(Cc2ccccc2)CCC1C>>CNC1CN(Cc2ccccc2)CCC1C,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US05364866,COc1ccc2c(c1)C(=O)OC2=O.NCCN1CCC(c2noc3cc(F)ccc23)CC1>>COc1ccc2c(c1)C(=O)N(CCN1CCC(c3noc4cc(F)ccc34)CC1)C2=O,,ClCCl,,,,test
US04466916,CC(C)(O)C#N.CC(N)CN>>CC1CNC(C)(C)C(=O)N1,,CC(C)=O,,O,,test
US20050043292A1,CC(C)(C)OC(=O)NC(CCCCN)C(=O)N1CC(F)(F)C(F)(F)C1.Cl.O=C(Cl)c1cccc(F)c1>>Cl.N[C@@H](CCCCNC(=O)c1cccc(F)c1)C(=O)N1CC(F)(F)C(F)(F)C1,,CCOCC,ClCCl,CCN(CC)CC,,test
US06355653B1,NC(CS(=O)(=O)c1ccccc1)=NNC(=O)c1ccc(F)cc1F>>O=S(=O)(Cc1n[nH]c(-c2ccc(F)cc2F)n1)c1ccccc1,,CCO,,,,test
US06670194B1,N#CCCCOCCOCCOCCCC#N>>NCCCCOCCOCCOCCCCN,,C1CCOC1,,,,test
US20130096135A1,CC(=O)OCC(=O)N1CCN(C(=O)OC(C)(C)C)[C@H](C)C1>>CC(=O)OCC(=O)N1CCN[C@H](C)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04010177,NNC(=O)CO.S=C1CN=C(c2ccccc2Cl)c2cc(Cl)ccc2N1>>OCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2,,CCCCO,,,,test
US20060052599A1,CCOC(=O)/C=C/C(=O)CCl.NC(=S)N[C@@H]1CCN(CC2CCCCC2)C1>>CCOC(=O)/C=C/c1csc(N[C@@H]2CCN(CC3CCCCC3)C2)n1.Cl,,CC#N,,CCOC(C)=O,,test
US20100256126A1,CCOC(C)=O.CC[C@H](NC(=O)C1(c2ccccc2)CCNCC1)c1ccccc1.Fc1ccc(N2CCNCC2)cc1>>CC[C@H](NC(=O)C1(c2ccccc2)CCN(C(=O)N2CCN(c3ccc(F)cc3)CC2)CC1)c1ccccc1,,C1CCOC1,,CCCCCCC,,test
US05801170,COC(=O)c1ccc(Br)c(C)c1.O=C(O)c1ccc(B(O)O)cc1>>COC(=O)c1ccc(-c2ccc(C(=O)O)cc2)c(C)c1,,CN(C)C=O,,CCN(CC)CC,,test
US20140045862A1,COc1ccc(CN(c2ccncn2)S(=O)(=O)c2cc(Cl)c(O[C@H]3C[C@H](O[Si](C)(C)C(C)(C)C)CC[C@@H]3c3ccnn3C)cc2F)c(OC)c1>>Cn1nccc1[C@H]1CC[C@@H](O)C[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20160264575A1,CC(C)(C)OC(=O)N1Cc2c(c3ccccc3n2Cc2ccc(F)cc2)CC1(C)C(=O)O>>CC1(C(=O)O)Cc2c(n(Cc3ccc(F)cc3)c3ccccc23)CN1,,C1COCCO1,O,CCN(CC)CC,Cl,test
US06710057B2,NCC1CCN(c2ccncc2)CC1.O=[N+]([O-])c1cccnc1Cl>>O=[N+]([O-])c1cccnc1NCC1CCN(c2ccncc2)CC1,,CCO,,CCN(CC)CC,,test
US20100048610A1,CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1O.COC(=O)c1cc(Cl)ncc1[N+](=O)[O-]>>CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1Oc1cc(C(=O)OC)c([N+](=O)[O-])cn1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US05302720,N.S=C=Nc1ccccc1-c1ccccc1>>NC(=S)Nc1ccccc1-c1ccccc1,,CCO,,,,test
US20150148313A1,COB(OC)OC.Cc1cc(Br)ccc1[C@@H](CF)COCc1ccccc1>>Cc1cc(B(O)O)ccc1[C@@H](CF)COCc1ccccc1,,C1CCOC1,CCOC(C)=O,Cl,[Li]CCCC,test
US05359087,CC(C)(C)OC(=O)N[C@@H](CC1=CC(=O)NC1=O)C(=O)OC(C)(C)C>>N[C@@H](CC1=CC(=O)NC1=O)C(=O)O,,O=C(O)C(F)(F)F,,,,test
US20150119362A1,O=[N+]([O-])c1ccc(CBr)cc1.c1cn[nH]c1>>O=[N+]([O-])c1ccc(Cn2cccn2)cc1,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20070142386A1,CC(C)C[C@H](CO)N(C)c1nc(S(=O)(=O)Cc2ccccc2)nc2nc(N)sc12.Cc1ccccc1CO>>Cc1ccccc1COc1nc(N(C)[C@@H](CO)CC(C)C)c2sc(N)nc2n1,,C1CCOC1,CCOC(C)=O,[Li]CCCC,[Cl-].[NH4+],test
US20120219522A1,O=P(Cl)(Cl)Cl.Oc1ccnc2cc(OCc3ccccc3)ccc12>>Clc1ccnc2cc(OCc3ccccc3)ccc12,,CCOC(C)=O,Cc1ccccc1,[Na+].[OH-],,test
US04317823,CNC.Cc1nn(C)c(C(=O)Cl)c1[N+](=O)[O-]>>Cc1nn(C)c(C(=O)N(C)C)c1[N+](=O)[O-],,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20140187588A1,C[C@@H]1OC(=O)[C@@H](N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)CCC[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>C[C@@H]1OC(=O)[C@@H](N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)CCC[C@H](O)[C@H]1O,[Pd],CCOC(C)=O,,,,test
US20150232472A1,CC(Br)C(=O)C(F)(F)F.CNC(=O)c1cc(Cl)nnc1N>>CNC(=O)C1=CC(Cl)=NN2C1=NC(O)(C(F)(F)F)C2C,,CCO,,O=C([O-])O.[Na+],,test
US06034246,CC(=O)Nc1ccc(-c2nc3ccccc3s2)cc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(=S)Nc1ccc(-c2nc3ccccc3s2)cc1,,O,,,,test
US20140051692A1,C=CCCCBr.C=CCN1CCOc2ccc(-c3c([C@H](OC(C)(C)C)C(=O)OC)c(C)nc4cc(-c5cccc(-c6ccccc6O)c5)nn34)c(Cl)c21>>C=CCCCOc1ccccc1-c1cccc(-c2cc3nc(C)c([C@H](OC(C)(C)C)C(=O)OC)c(-c4ccc5c(c4Cl)N(CC=C)CCO5)n3n2)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030225064A1,CC(=O)c1ccc(-c2ccco2)cc1C.CCOC(=O)C(F)(F)F>>Cc1cc(-c2ccco2)ccc1C(=O)CC(=O)C(F)(F)F,,COC(C)(C)C,,Cl,C[O-].[Na+],test
US20100190747A1,FC(F)(F)CI.O=c1c2cc[nH]c2[nH]c(=S)n1-c1ccc(OCC(F)(F)F)cc1>>O=c1c2cc[nH]c2nc(SCC(F)(F)F)n1-c1ccc(OCC(F)(F)F)cc1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20140018373A1,CNc1ccc(C(F)(F)F)cn1.O=C1CCC(=O)N1Br>>CNc1ncc(C(F)(F)F)cc1Br,,CN(C)C=O,,[Cl-].[NH4+],,test
US04814459,CCOC(=O)CN.Clc1nc2ccccc2o1>>CCOC(=O)CNc1nc2ccccc2o1,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US20050004142A1,NC1=c2ccoc2=NCN1c1ccc(N)cc1.O=C(Cl)C1(c2ccc(Cl)c(Cl)c2)CC1>>NC1=c2ccoc2=NCN1c1ccc(NC(=O)C2(c3ccc(Cl)c(Cl)c3)CC2)cc1,,c1ccncc1,,,,test
US20070037836A1,CN(C)c1nc(Cl)nc2ccccc12.NC1CCN(Cc2ccccc2)C1>>CN(C)c1nc(NC2CCN(Cc3ccccc3)C2)nc2ccccc12,,CCCCO,,O=C([O-])O.[Na+],,test
US05212187,CN(CCCCN)CCC(c1ccc(Cl)cc1)c1ccccn1.NCCCOc1cccc(CN2CCCCC2)c1.O=C(n1ccnc1)n1ccnc1>>CN(CCCCNC(=O)NCCCOc1cccc(CN2CCCCC2)c1)CCC(c1ccc(Cl)cc1)c1ccccn1,,CCOC(C)=O,CO,,,test
US06875759B1,Cc1ccc(N=C=Nc2ccc(C)cc2)cc1.N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1>>Cc1ccc(NC(=N)N(c2ccc(C)cc2)C(Cc2c[nH]c3ccccc23)C(=O)OCc2ccccc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US05451691,CCCCC/C=C\C/C=C\CCCCCCCC(=O)OCCCCCCCCCCCCCCCCCCCCCC(=O)OC(C)(C)C>>CCCCC/C=C\C/C=C\CCCCCCCC(=O)OCCCCCCCCCCCCCCCCCCCCCC(=O)O,,c1ccccc1,,,,test
US06046186,CN(C)c1c(OCc2ccccc2)ccc2c1CC[C@H]1[C@@H]3CCC(=O)[C@@]3(C)CC[C@H]21>>CN(C)c1c(O)ccc2c1CC[C@H]1[C@@H]3CCC(=O)[C@@]3(C)CC[C@H]21,[Pd],C1CCOC1,,,,test
US20040014746A1,CCSC(C)=S.NC[C@H]1CN(c2ccc(C3=NNC(=O)CS3)c(F)c2)C(=O)O1>>CC(=S)NC[C@H]1CN(c2ccc(C3=NNC(=O)CS3)c(F)c2)C(=O)O1,,CN(C)C=O,,CCN(CC)CC,,test
US20130178540A1,CCCCCCCCCCCCCCCCCCOC(=O)C(O)CCSC.O=C(OO)c1cccc(Cl)c1>>CCCCCCCCCCCCCCCCCCOC(=O)C(O)CCS(C)=O,,ClCCl,,,,test
US20030199553A1,COC(=O)c1ccc(NC(=O)c2cc3ccccc3[nH]2)c2c1OCCCO2>>O=C(Nc1ccc(C(=O)O)c2c1OCCCO2)c1cc2ccccc2[nH]1,,C1CCOC1,,[Na+].[OH-],,test
US20030065179A1,CC(=O)O[C@H](C)c1nccc(N2CCc3ccc(S(=O)(=O)N(C)C)cc3C2)n1>>C[C@@H](O)c1nccc(N2CCc3ccc(S(=O)(=O)N(C)C)cc3C2)n1,,CO,O,[Li+].[OH-],,test
US20120302566A1,CC(C)(C)[Si](C)(C)O[C@H]1CCc2c(Br)cccc21.CCOC(=O)C(F)(F)F>>CC(C)(C)[Si](C)(C)O[C@H]1CCc2c(C(=O)C(F)(F)F)cccc21,,C1CCOC1,,[Li]CCCC,,test
US20040063704A1,COc1ccc(C=C2CCN(C(=O)OC(C)(C)C)CC2)cc1F>>COc1ccc(CC2CCN(C(=O)OC(C)(C)C)CC2)cc1F,[Pd],CO,,[H][H],,test
US20080261941A1,FC(F)(F)c1ccc(Cl)nc1.Oc1cc(F)cc(Br)c1>>Fc1cc(Br)cc(Oc2ccc(C(F)(F)F)cn2)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060189673A1,C=C(C)CCl.Cc1cc(C)c(C)c(O)c1>>CC(C)=COc1cc(C)cc(C)c1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04642313,CCOC(=O)CC(NC(=O)c1ccccc1)C(=O)c1ccco1>>CCOC(=O)Cc1nc(-c2ccccc2)oc1-c1ccco1,,ClC(Cl)Cl,,O=P(Cl)(Cl)Cl,,test
US20130072473A1,CC(=O)Nc1cc2c(s1)CN(C(=O)OC(C)(C)C)CC2.O=C1CCC(=O)N1I>>CC(=O)Nc1sc2c(c1I)CCN(C(=O)OC(C)(C)C)C2,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,ClCCl,,,test
US20120202856A1,COC(=O)c1oc(C(C)(C)C)nc1C>>Cc1nc(C(C)(C)C)oc1C(=O)O,,CO,,[Na+].[OH-],,test
US20160159820A1,CCOC(=O)[C@@H]1[C@H]2Oc3ccc(Oc4ccnc(C(=O)NC)c4)cc3[C@H]21>>CNC(=O)c1cc(Oc2ccc3c(c2)[C@@H]2[C@H](O3)[C@H]2C(=O)O)ccn1,,C1CCOC1,O,[Na+].[OH-],,test
US06734200B1,CC1(C)OC[C@@H](C(=O)N2CC=C(c3ccc(N4C[C@H](CN(C(=O)OCC(Cl)(Cl)Cl)c5ccon5)OC4=O)cc3F)CC2)O1>>O=C([C@@H](O)CO)N1CC=C(c2ccc(N3C[C@H](CNc4ccon4)OC3=O)cc2F)CC1,[Zn],CC(=O)O,,O,,test
US05631373,Cc1cc(C)c(N)c([N+](=O)[O-])c1>>Cc1cc(N)c(N)cc1C,[Pd],,,CCO,,test
US04687775,CC(=O)OCc1cccn2c(C)c(C)nc12.Sc1nc2ccccc2[nH]1>>Cc1nc2c(CSc3nc4ccccc4[nH]3)cccn2c1C,,Br,CC(=O)O,,,test
US20080160028A1,CCCC(=O)OC(=O)CCC.COc1ccc(-c2cc(C)c3c(N)c(C(N)=O)sc3n2)cc1OC>>CCCc1nc2c(sc3nc(-c4ccc(OC)c(OC)c4)cc(C)c32)c(=O)[nH]1,,Cc1ccccc1,,,,test
US20050197328A1,C=CC1CCN(C(=O)OC(C)(C)C)CC1.CCn1c(-c2nonc2N)nc2cncc(Br)c21>>CCn1c(-c2nonc2N)nc2cncc(CCC3CCNCC3)c21,,C1CCOC1,ClCCl,B1C2CCCC1CCC2,[Na+].[OH-],test
US20040254205A1,COc1cc2nc[nH]c(=O)c2c([N+](=O)[O-])c1OC.Nc1cccc(Br)c1>>COc1cc2ncnc(Nc3cccc(Br)c3)c2c([N+](=O)[O-])c1OC,CN(C)C=O,O=S(Cl)Cl,,,,test
US20120283297A1,Cc1cc2[nH]ncc2cc1C#N.NO>>Cc1cc2[nH]ncc2cc1C(=N)NO,,CCO,,Cl,O=C([O-])O.[Na+],test
US20130045964A1,CC(C)(C)OC(=O)CNC(=O)C(O)c1ccc(-c2noc(-c3cnn(-c4ccccc4)c3C(F)(F)F)n2)cc1>>O=C(O)CNC(=O)C(O)c1ccc(-c2noc(-c3cnn(-c4ccccc4)c3C(F)(F)F)n2)cc1,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20110301180A1,CO.O=C(O)Cc1nnn[nH]1>>COC(=O)Cc1nnn[nH]1,,O,,O=S(=O)(O)O,,test
US20160122344A1,COC(=O)Cc1ccc(OC)c(O)c1.COCCCBr>>COCCCOc1cc(CC(=O)OC)ccc1OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04539406,C[Si](C)(Cl)Cl.Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1>>Cc1cc(C(C)(C)C)c(O[Si](C)(C)Cl)c(C(C)(C)C)c1,,CCN(CC)CC,,CC#N,,test
US20140128392A1,COC(=O)c1ccc2nc(-c3ccccc3)c(-c3cccc(OC)c3)nc2c1>>COc1cccc(-c2nc3cc(CO)ccc3nc2-c2ccccc2)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20160221990A1,BrCC1CC1.Fc1cc(/C=C/c2ccc(N3CCNCC3)cc2)cc(-c2ccncc2)c1>>Fc1cc(/C=C/c2ccc(N3CCN(CC4CC4)CC3)cc2)cc(-c2ccncc2)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US06194410B1,CN1CCNCC1.CSc1nn2c(Cl)cc(CN3CCOCC3)nc2c1S(=O)(=O)c1ccccc1>>CSc1nn2c(N3CCN(C)CC3)cc(CN3CCOCC3)nc2c1S(=O)(=O)c1ccccc1,,CN(C)C=O,,,,test
US20130150407A1,COC(=O)Cc1cc2ccc(F)cc2c(C2CCNCC2)c1C.O=C=Nc1ccc(Cl)cc1Cl>>COC(=O)Cc1cc2ccc(F)cc2c(C2CCN(C(=O)Nc3ccc(Cl)cc3Cl)CC2)c1C,,CO,O,,,test
US20160021883A1,Cl.N#Cc1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1>>Cl.NCc1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1,[Pd],CCO,,,,test
US20100113774A1,COC(=O)Cn1c(=O)[nH]c2ccccc2c1=O.COc1cc(OC)c(NC(=O)CBr)cc1Cl>>COC(=O)Cn1c(=O)c2ccccc2n(CC(=O)Nc2cc(Cl)c(OC)cc2OC)c1=O,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04845097,CCOCCc1ccc(OCCN)c(C)c1.Cc1nc(C)c(Cl)c(Cl)n1>>CCOCCc1ccc(OCCNc2nc(C)nc(C)c2Cl)c(C)c1,,Cc1ccccc1,,CCN(CC)CC,,test
US20120040968A1,CCc1nc(C(N)=O)c(Cl)nc1Cl.CS(=O)(=O)c1ccc(N)cc1Cl.N[C@H]1CC[C@H](O)CC1>>CCc1nc(C(N)=O)c(Nc2ccc(S(C)(=O)=O)c(Cl)c2)nc1N[C@@H]1CC[C@@H](O)CC1,,CCO,CCOC(C)=O,CN1CCCC1=O,,test
US20100298290A1,CC(C)(C)OC(=O)N1CCOc2ccc(-c3cnc(N)c(N)c3)cc2C1.COC(=O)N=C(NC(=O)OC)SC>>COC(=O)Nc1nc2ncc(-c3ccc4c(c3)CN(C(=O)OC(C)(C)C)CCO4)cc2[nH]1,,CC(=O)O,,,,test
US20160046617A1,COC(=O)CCNC(=O)c1cc(-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)N(Cc3ccc(OC)cc3OC)c3ncns3)cc2Cl)ccn1>>COc1ccc(CN(c2ncns2)S(=O)(=O)c2cc(Cl)c(Oc3ccc(Cl)cc3-c3ccnc(C(=O)NCCC(=O)O)c3)cc2F)c(OC)c1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20160200725A1,CN.COc1cc(OC)c(Cl)c(-c2cc3cnc(S(C)(=O)=O)nc3n(CCOC3CN(C(=O)OC(C)(C)C)C3)c2=O)c1Cl>>CNc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)c(=O)n(CCOC3CN(C(=O)OC(C)(C)C)C3)c2n1,,CC(C)(C)O,,,,test
US20030199440A1,CC(C)CC(NC(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1)C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CC(C)CC(NC(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1)C(=O)O.O=C(O)C(F)(F)F,,Cc1ccccc1,,,,test
US04268675,CC(Oc1ccc(Cl)c(Cl)c1)c1nnc(N=C=O)s1.CNCC(OC)OC>>COC(CN(C)C(=O)Nc1nnc(C(C)Oc2ccc(Cl)c(Cl)c2)s1)OC,,CCCCCC,,c1ccccc1,,test
US20140206864A1,C=O.Cc1ccccc1.Nc1ccccc1.Oc1ccccc1>>C1=Cc2ccccc2ON1,,CCO,,,,test
US04143055,CCOC(=O)Cl.COc1cc(N)c2c(c1)OC(C)C2>>CCOC(=O)Nc1cc(OC)cc2c1CC(C)O2,,c1ccccc1,,CCN(CC)CC,,test
US20070197393A1,COC(=O)c1ccc(OC)cc1O.COC(Cl)Cl>>COC(=O)c1ccc(OC)c(C=O)c1O,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US05668143,COC(=O)c1cc(=O)c2ccccc2o1.O=C=NS(=O)(=O)c1ccccc1>>COC(=O)c1cc(=NS(=O)(=O)c2ccccc2)c2ccccc2o1,,CC#N,,,,test
US20060128793A1,CNC1CCN(C)C1.COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CC[C@H](O)[C@@]2(C)C[C@H]1OC(C)=O>>COC[C@H]1OC(=O)/C(=C/N(C)C2CCN(C)C2)C2=C(O)C(=O)C3=C([C@H](OC(C)=O)C[C@@]4(C)C3CC[C@@H]4O)[C@]21C,,ClCCl,,,,test
US20080045505A1,CCOC(=O)c1ccc(O)cc1.OC1CCOCC1>>CCOC(=O)c1ccc(OC2CCOCC2)cc1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05077303,COC=C(C(=O)OC)c1ccccc1C=Cc1ccccc1.O=C(OO)c1cccc(Cl)c1>>COC=C(C(=O)OC)c1ccccc1[C@@H]1O[C@H]1c1ccccc1,,ClCCl,,,,test
US20140135330A1,CC[C@H](N)C(=O)O.O=C(Cl)OCc1ccccc1>>CC[C@H](NC(=O)OCc1ccccc1)C(=O)O,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20120208817A1,CCOc1cc(C=O)cc([N+](=O)[O-])c1O.NC(N)=O.O=C(Cc1ccccc1)c1ccc(F)c(F)c1>>CCOc1cc(C2NC(=O)NC(c3ccc(F)c(F)c3)=C2c2ccccc2)cc([N+](=O)[O-])c1O,,CCO,,Cl,,test
US20150018363A1,Cc1c(C(N)=O)nc2ccc(I)cn12>>Cc1c(C#N)nc2ccc(I)cn12,,O=P(Cl)(Cl)Cl,,,,test
US20070225275A1,CSc1nc(O)c2c(n1)CCN(C(=O)OC(C)(C)C)CC2.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CSc1nc2c(c(OS(=O)(=O)C(F)(F)F)n1)CCN(C(=O)OC(C)(C)C)CC2,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20110166116A1,CS(=O)(=O)c1ccc(N2CCC(=NOC3CCN(c4ccccn4)CC3)CC2)c(F)c1.Cn1cccc1C=O>>Cn1cccc1CN1CCC(ON=C2CCN(c3ccc(S(C)(=O)=O)cc3F)CC2)CC1,,ClCCl,,CCN(CC)CC,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140221417A1,CCOC(=O)Cc1c(SC(C)=O)[nH]c2ccccc12.COc1ccc(N(C)C(=O)[C@H](Cc2cccc(CCl)c2)NC(=O)OC(C)(C)C)cc1>>CCOC(=O)Cc1c(SCc2cccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)N(C)c3ccc(OC)cc3)c2)[nH]c2ccccc12,,CCO,,Cl,[K+].[OH-],test
US20120196864A1,COc1cc(C=O)ccc1Oc1ccc(C#N)cc1C(F)(F)F.N=C1CNC(=O)N1C(=O)c1ccccc1>>COc1cc(/C=C2\NC(=O)N=C2N)ccc1Oc1ccc(C#N)cc1C(F)(F)F,,CCO,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US20110034497A1,O=C(NCC1CC1)c1cncc(-c2ccc3c(c2)c(-c2nc4c(-c5cccnc5)cncc4[nH]2)nn3C2CCCCO2)c1>>O=C(NCC1CC1)c1cncc(-c2ccc3[nH]nc(-c4nc5c(-c6cccnc6)cncc5[nH]4)c3c2)c1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20030045432A1,C=CCc1c(C)cc(C)cc1OC(F)F.O=[O+][O-]>>Cc1cc(C)c(CC=O)c(OC(F)F)c1,,ClCCl,,,,test
US20140249133A1,OCC(O)CBr.Oc1cnc(-c2nn(Cc3ccccc3F)c3ccccc23)nc1Nc1ccncc1>>OCC(O)COc1cnc(-c2nn(Cc3ccccc3F)c3ccccc23)nc1Nc1ccncc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040214817A1,CCc1ccc([N+](=O)[O-])cc1.O=C1CCC(=O)N1Br>>CC(Br)c1ccc([N+](=O)[O-])cc1,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20080009530A1,CC(C)CCS(N)(=O)=O.CC(C)Oc1cc(/C=C/C(=O)O)n(Cc2ccc(C(F)(F)F)cc2Cl)n1>>CC(C)CCS(=O)(=O)NC(=O)/C=C/c1cc(OC(C)C)nn1Cc1ccc(C(F)(F)F)cc1Cl,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US04072760,CC(C)(C)NCC(O)c1ccc(O)c(NC(=O)c2ccc([N+](=O)[O-])cc2)c1.Cl>>CC(C)(C)NCC(O)c1ccc(O)c(NC(=O)c2ccc(N)cc2)c1.Cl,O=[Pt]=O,CO,,[H][H],,test
US20090247746A1,CC(O)c1cccc2cc(-c3nccs3)[nH]c12.Cn1ccnc1S>>CC(Sc1nccn1C)c1cccc2cc(-c3nccs3)[nH]c12,,C1CCOC1,O,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US03962438,O=C(OO)c1cccc(Cl)c1.O=c1[nH]c(=O)n2c3c(cccc13)Sc1ccc(C(F)(F)F)cc1-2>>O=c1[nH]c(=O)n2c3c(cccc13)S(=O)c1ccc(C(F)(F)F)cc1-2,,CO,,,,test
US20070093521A1,O=S(Cl)Cl.O=[N+]([O-])c1cccc2nc(S)oc12>>O=[N+]([O-])c1cccc2nc(Cl)oc12,,Cc1ccccc1,,CN(C)C=O,,test
US20150344466A1,CCOC(=O)c1cc(Cc2cccc(OC)c2)on1>>COc1cccc(Cc2cc(C(=O)O)no2)c1,,O,,CCO,[Na+].[OH-],test
US20080081821A1,CCOC(=O)CS.CCOC(=O)c1ccncc1Cl>>CCOC(=O)c1sc2cnccc2c1O,,CN(C)C=O,,[H-].[Na+],,test
US20080269305A1,CC(C)(C)OC(=O)c1ccccc1-c1ccc(CBr)cc1.CCCCc1nc(Cl)c(C=O)[nH]1>>CCCCc1nc(Cl)c(C=O)n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150119380A1,Nc1ncccn1.O=C(CBr)c1cc2ccc(F)cc2oc1=O>>Br.O=c1oc2cc(F)ccc2cc1-c1cn2cccnc2n1,,CCO,O,,,test
US20140343035A1,C#Cc1cc(OC)cc(OC)c1.CC(C)(C)OC(=O)N1CC[C@H](n2cc(I)c3c(N)ncnc32)C1>>COc1cc(C#Cc2cn([C@H]3CCN(C(=O)OC(C)(C)C)C3)c3ncnc(N)c23)cc(OC)c1,[Cu]I,C1CCOC1,O,CCN(CC)CC,CCOC(C)=O,test
US05952351,CCn1c(=O)n(C2CCNCC2)c2ccccc21.O=C1c2ccccc2S(=O)(=O)N1CCCCBr>>CCn1c(=O)n(C2CCN(CCCCN3C(=O)c4ccccc4S3(=O)=O)CC2)c2ccccc21,,O,,CCOCC,,test
US20100233116A1,[N-]=[N+]=NCc1ccc(C(F)F)o1>>NCc1ccc(C(F)F)o1,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20030092677A1,Cc1cn(-c2cccc(C(=O)CC(=O)Nc3cc(C#Cc4ccc(F)cc4)ccc3NC(=O)OC(C)(C)C)c2)cn1>>Cc1cn(-c2cccc(C3=Nc4ccc(C#Cc5ccc(F)cc5)cc4NC(=O)C3)c2)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080242665A1,Cc1c(CN2CCNCC2)sc2c(N3CCOCC3)nc(Cl)nc12.O=S(=O)(Cl)c1ccccc1>>Cc1c(CN2CCN(S(=O)(=O)c3ccccc3)CC2)sc2c(N3CCOCC3)nc(Cl)nc12,,ClCCl,,CCN(CC)CC,,test
US20040023968A1,CC1=CC(=O)OC1=O.Nc1cccc(Cc2n[nH]c(=O)c3ccccc23)c1>>CC1=CC(=O)N(c2cccc(Cc3n[nH]c(=O)c4ccccc34)c2)C1=O,,O,,CC(=O)O,,test
US20090029965A1,CC(C)(C)CCN1CCC(C(=O)O)CC1.Cc1cc(C(=O)N(C)c2ccc(Cl)cc2)ccc1CN>>Cc1cc(C(=O)N(C)c2ccc(Cl)cc2)ccc1CNC(=O)C1CCN(CCC(C)(C)C)CC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030171418A1,C[C@@H](Cn1ncc2ccc(OCc3ccccc3)cc21)O[Si](C)(C)C(C)(C)C>>C[C@@H](Cn1ncc2ccc(O)cc21)O[Si](C)(C)C(C)(C)C,[Pd],CO,,,,test
US20150299219A1,CC(C)(C)OC(=O)N(NC(=O)COCCO)c1ccccc1>>CC(C)(C)OC(=O)N(c1ccccc1)N1CCOCC1=O,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140031351A1,CN(c1ccc(Br)cc1[N+](=O)[O-])S(C)(=O)=O>>CN(c1ccc(Br)cc1N)S(C)(=O)=O,[Fe],C1CCOC1,CC(=O)O,,,test
US20100093730A1,CCOC(=O)CBr.O=C1NCCC1(c1ccc(F)cc1)c1ccc(F)cc1>>CCOC(=O)CN1CCC(c2ccc(F)cc2)(c2ccc(F)cc2)C1=O,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20140336377A1,COC(=O)c1cccc(OCC(F)(F)F)n1>>OCc1cccc(OCC(F)(F)F)n1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120225854A1,BrBr.CC(C)(C)OC(=O)N1CCN(c2ccc(C(C)(O)C(F)(F)F)cc2)CC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(C(C)(O)C(F)(F)F)cc2Br)CC1,,CCO,,,,test
US20070049618A1,CN(C)CCOc1ccc([N+](=O)[O-])c(F)c1.Oc1ccccc1>>CN(C)CCOc1ccc([N+](=O)[O-])c(Oc2ccccc2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120071461A1,CN(C(=O)OC(C)(C)C)C1CCN(c2ccnc(C#N)c2)CC1>>CNC1CCN(c2ccnc(C#N)c2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080221132A1,CC(=O)O.COc1cc2nc[nH]c(=O)c2cc1O>>COc1cc2nc[nH]c(=O)c2cc1OC(C)=O,,Br,,O,,test
US20080009530A1,CCOC(=O)/C=C/c1ccc(OCCC2OCCO2)cc1Oc1ncc(C(F)(F)F)cc1Cl>>O=C(O)/C=C/c1ccc(OCCC2OCCO2)cc1Oc1ncc(C(F)(F)F)cc1Cl,,CCO,,C1CCOC1,[Na+].[OH-],test
US06087512,ClCC1CO1.NC(=O)Cc1ccc(O)cc1>>NC(=O)Cc1ccc(OC[C@@H]2CO2)cc1,,O,,[Na+].[OH-],,test
US05811556,CC(C)[C@H]1c2ccc(F)cc2CC[C@]1(O)CC(=O)OC(C)(C)C>>CC(C)[C@H]1c2ccc(F)cc2CC[C@]1(O)CC(=O)O,,O,,O=CO,,test
US20100331326A1,Brc1ccc2nccn2c1.Cc1ccncc1N1CCNC1=O>>Cc1ccncc1N1CCN(c2ccc3nccn3c2)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20100087427A1,CC(C)(C)OC(=O)N1CC(CNc2ccc(Cl)cc2)C(Cc2ccccc2)C1.N#Cc1cccc(CBr)c1>>CC(C)(C)OC(=O)N1CC(Cc2ccccc2)C(CN(Cc2cccc(C#N)c2)c2ccc(Cl)cc2)C1,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20100056576A1,O=C1CC=C(c2ccncc2[N+](=O)[O-])CC1>>O=[N+]([O-])c1cnccc1C1=CCC(O)CC1,,CO,,[BH4-].[Na+],,test
US20150344473A1,CC(C)(C)OC(=O)N1CC[C@@H](Oc2ccc(-c3ncnc4[nH]c(-c5ccc(N6CCOCC6)cc5)nc34)cc2C#N)C1>>N#Cc1cc(-c2ncnc3[nH]c(-c4ccc(N5CCOCC5)cc4)nc23)ccc1O[C@@H]1CCNC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20040171605A1,CC(C)(C)OC(=O)N1CC[C@H]1CO.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.OC[C@@H]1CCN1,,ClCCl,,,,test
US20090281114A1,CCOC(=O)c1ccc2[nH]c([Si](C)(C)C)c(CCCO[Si](C)(C)C(C)(C)C)c2c1>>CCOC(=O)c1ccc2[nH]cc(CCCO)c2c1,,CC#N,,,,test
US20030027849A1,COC(=O)C(F)(F)CNC(=O)OCc1ccccc1>>O=C(NCC(F)(F)C(=O)O)OCc1ccccc1,,CO,,C1CCOC1,[Na+].[OH-],test
US20120264735A1,CCC(=O)O.Cn1cc(-n2ccc(=O)c(Cc3cccc(C(=N)NO)c3)n2)cn1>>CCc1nc(-c2cccc(Cc3nn(-c4cnn(C)c4)ccc3=O)c2)no1,,CN(C)C=O,,ClCCCl,,test
US20130261125A1,COC1(Cc2ccccc2F)CCCC(NC(=O)c2ccc3c(c2)c(-c2ccnc(C)c2)nn3C(c2ccccc2)(c2ccccc2)c2ccccc2)C1>>COC1(Cc2ccccc2F)CCCC(NC(=O)c2ccc3[nH]nc(-c4ccnc(C)c4)c3c2)C1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20100016279A1,CC(C)(C)OC(=O)N1CCC(c2c[nH]c3ncccc23)CC1>>c1cnc2[nH]cc(C3CCNCC3)c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100144706A1,CC(C)(C)OC(=O)N1CC[C@@H](Nc2cccc([N+](=O)[O-])c2)C1>>CC(C)(C)OC(=O)N1CC[C@@H](Nc2cccc(N)c2)C1,[Ni],CO,,,,test
US04379932,CN1CCC2(CC1)CNc1ccccc12.Fc1ccccc1>>CN1CCC2(CC1)CN(c1ccccc1)c1ccccc12,,CS(C)=O,,O,[H-].[Na+],test
US05760059,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NNc1ccccc1>>CC(C)(C)OC(=O)NNc1ccccc1,,C1CCOC1,,,,test
US20030013757A1,COC(=O)c1ccc(C(=O)O)s1.NCc1cccc2ccccc12>>COC(=O)c1ccc(C(=O)NCc2cccc3ccccc23)s1,,ClCCl,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20100331314A1,O=Cc1cnn2ccc(Cl)nc12.Oc1cccc(Cl)c1>>O=Cc1cnn2ccc(Oc3cccc(Cl)c3)nc12,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120232081A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2c(Cc3c(F)cccc3Cl)c(-c3ccccc3)c3ccccn23)CC1>>O=C(c1c(Cc2c(F)cccc2Cl)c(-c2ccccc2)c2ccccn12)N1CCNCC1,,ClCCl,,C1COCCO1,Cl,test
US05955480,CC(C)(C)OC(=O)OC(C)(C)C.Fc1ccc(-c2nc(-c3ccc(Oc4ccccc4)cc3)[nH]c2-c2ccncc2)cc1>>CC(C)(C)OC(=O)n1c(-c2ccc(Oc3ccccc3)cc2)nc(-c2ccncc2)c1-c1ccc(F)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20050250822A1,C=C(c1ccc(Cl)cc1)c1ccc(NC(=O)OC(C)(C)C)c(C)c1.CC=NO>>CC1=NOC(c2ccc(Cl)cc2)(c2ccc(NC(=O)OC(C)(C)C)c(C)c2)C1,,O,,CCN(CC)CC,CN(C)C=O,test
US20060014803A1,CCCOc1cc2c(cc1[Se]c1ccc(C(=O)OCC)cn1)C(C)(C)CCC2(C)C>>CCCOc1cc2c(cc1[Se]c1ccc(C(=O)O)cn1)C(C)(C)CCC2(C)C,,CCO,,[Na+].[OH-],,test
US05449686,O=Cc1ccc(OC(F)F)c(OCC2CC2)c1>>OCc1ccc(OC(F)F)c(OCC2CC2)c1,,CCO,,[Na+].[OH-],,test
US06174884B1,CCCCCCC(C)NN.CCOC(CC)=C(C#N)C#N.OO>>CCCCCCC(C)n1nc(CC)c(C(N)=O)c1N,,CCO,CO,N,,test
US20160002177A1,Brc1ccccc1COCCC1CCNCC1.C=O>>CN1CCC(CCOCc2ccccc2Br)CC1,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20110237832A1,COC(=O)/C=C/C=C/[C@@H](C)C(OC)c1ccc(N(C)C)cc1>>COC(c1ccc(N(C)C)cc1)[C@H](C)/C=C/C=C/C(=O)O,,CO,,[Li+].[OH-],,test
US20120101083A1,CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCNCC4)no2)cc1C#N.CC1(C)OCC(=O)CO1>>CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN(C3COC(C)(C)OC3)CC4)no2)cc1C#N,,ClCCl,,Cl,O=C([O-])O.[Na+],test
US20050004203A1,O=C(O)CCC(CCCSSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O>>O=C(O)CCC1CCCSC1=O,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20110288067A1,C[C@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3ccc(C(=O)N[C@H](C)C(C)(C)C)s3)nc12)C(C)(C)C>>C[C@H](NC(=O)c1c[nH]c2ncc(-c3ccc(C(=O)N[C@H](C)C(C)(C)C)s3)nc12)C(C)(C)C,,ClCCl,,,,test
US20060189604A1,CC(=O)O.CCOC(=O)[C@@H]1CC[C@@H](N[C@H](C)c2ccccc2)[C@@H](F)C1>>CC(=O)O.C[C@@H](N[C@@H]1CC[C@@H](C(=O)O)C[C@@H]1F)c1ccccc1,,CO,,[Li+].[OH-],,test
US20080318945A1,CC(C)(C)OC(=O)N[C@H](C=O)CO[Si](C)(C)C(C)(C)C.O=C(OCc1ccccc1)N1CCNCC1>>CC(C)(C)OC(=O)N[C@@H](CO[Si](C)(C)C(C)(C)C)CN1CCN(C(=O)OCc2ccccc2)CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US04612379,CC1(C)OC(=O)C(=CO)C(=O)O1>>CC1(C)OC=CC(=O)O1,,Cc1ccccc1,,CC(C)=O,,test
US20040147543A1,NCCOc1ccccc1.O=[N+]([O-])c1cnc2cc(-c3ccccc3)ccc2c1Cl>>O=[N+]([O-])c1cnc2cc(-c3ccccc3)ccc2c1NCCOc1ccccc1,,CCOCC,,,,test
US20020091150A1,CCCCO.O=C=NC(=O)C(c1ccccc1)c1ccccc1>>CCCCOC(=O)NC(=O)C(c1ccccc1)c1ccccc1,,ClCCl,,,,test
US20090306089A1,CS(=O)(=O)Cl.O=C1CCc2ccc(=O)n3c2N1C[C@H]3CO>>CS(=O)(=O)OC[C@@H]1CN2C(=O)CCc3ccc(=O)n1c32,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20060063759A1,CC1(C)OB(c2cccc(C=C3c4ccc(Cl)cc4CCc4cccnc43)c2)OC1(C)C.OO>>Oc1cccc(C=C2c3ccc(Cl)cc3CCc3cccnc32)c1,,C1CCOC1,,CC(=O)O,O,test
US05616610,CCC=O.COc1ccc(F)c2c1C[C@@H](NC1CCC1)CO2>>CCCN(C1CCC1)[C@H]1COc2c(F)ccc(OC)c2C1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20060094843A1,CCCCC1(C(=O)OCC)CCCC1O.Cc1cccc(C(=O)Cl)c1>>CCCCC1(C(=O)OCC)CCCC1OC(=O)c1cccc(C)c1,,c1ccncc1,,ClCCl,,test
US20150141400A1,CC(C)(C)OC(=O)NC1CNC1.CCOC(=O)c1cc(C(F)(F)F)c(C=O)c(Cl)c1N>>CC(C)(C)OC(=O)NC1CN(Cc2c(C(F)(F)F)cc(C(=O)O)c(N)c2Cl)C1,,ClC(Cl)Cl,,,,test
US20050049244A1,CC(C)(C)C[C@H](Nc1nc2ccccc2o1)C(=O)N[C@@H](COCc1ccccc1)CN1CCc2cc(F)ccc21>>CC(C)(C)C[C@H](Nc1nc2ccccc2o1)C(=O)N[C@@H](CO)CN1CCc2cc(F)ccc21,[Pd],C1COCCO1,CO,Cl,[H][H],test
US20130261178A1,NCCNC(=O)Nc1ccccc1O.c1cc(OCC2CO2)ccc1OCCOC1CCCC1>>O=C(NCCNCC(O)COc1ccc(OCCOC2CCCC2)cc1)Nc1ccccc1O,,CC(C)O,,Cl,,test
US04377580,COC(=O)C(=CNc1ncnc2cc(NC(=O)C(C)(C)C)ccc12)C(=O)OC>>COC(=O)c1cnc2c3ccc(NC(=O)C(C)(C)C)cc3ncn2c1=O,,c1ccc(Oc2ccccc2)cc1,,CCCCCC,,test
US05969146,COC[C@H]1CN(c2coc3cc(C=CC[C@@H](O)C(F)(F)F)ccc23)C(=O)O1>>COC[C@H]1CN(c2coc3cc(CCC[C@@H](O)C(F)(F)F)ccc23)C(=O)O1,[Pd],CCO,,,,test
US20050197340A1,CSc1nc(Cl)cc(Cl)n1.O=Cc1ccccc1Cl>>CSc1nc(Cl)c(C(O)c2ccccc2Cl)c(Cl)n1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20080176850A1,O=[N+]([O-])c1ccc(C2CC2)c2ccccc12>>Nc1ccc(C2CC2)c2ccccc12,[Pd],CCO,,,,test
US20060063789A1,CO.NC(=O)c1cccc(N)c1.O=[N+]([O-])c1cnc(Cl)nc1NCc1ccccc1>>Cc1cc(C)c(Nc2ccnc(Cl)n2)c(C)c1,,CN(C)C=O,,CCN(CC)CC,,test
US05200552,C=C(C)C(=O)N=C=O.Nc1ccc([N+](=O)[O-])cc1>>C=C(C)C(=O)NC(=O)Nc1ccc([N+](=O)[O-])cc1,,CCOCC,,,,test
US04824855,CC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(=O)OCC1CC1.CC(=O)CC(=O)OCCN(C)C.N>>CC1=C(C(=O)OCCN(C)C)C(c2cccc([N+](=O)[O-])c2)C(C(=O)OCC2CC2)=C(C)N1,,CCO,,,,test
US04026891,COC(=O)CCC(=O)c1ccc(NC(=O)C(C)C)c([N+](=O)[O-])c1>>COC(=O)CCC(=O)c1ccc(NC(=O)C(C)C)c(N)c1,,CCO,,,,test
US20050272753A1,O=[N+]([O-])c1ccc(N2CCC(O)C2)cc1.[C-]#N>>N#CC1CCN(c2ccc(N)cc2)C1,,C1CCOC1,CN1CCCC1=O,CCN(CC)CC,CS(=O)(=O)Cl,test
US20150366977A1,O=C(Cl)c1ccc(Cl)c(S(=O)(=O)Cl)c1.O=C1CCNCC1>>O=C1CCN(C(=O)c2ccc(Cl)c(S(=O)(=O)Cl)c2)CC1,,Clc1ccccc1,,Cl,,test
US20140080989A1,CC(C)O.O=C(O)c1cc(O)ccc1O>>CC(C)Oc1ccccc1C(=O)O,,CCCCCC,,O=S(=O)(O)O,,test
US20070265265A1,CCCCC(=O)Cl.Nc1ccc(-c2csc(NC(=O)[C@@H]3CCCN3C(=O)OCc3ccccc3)n2)cc1>>CCCCC(=O)Nc1ccc(-c2csc(NC(=O)C3CCCN3C(=O)OCc3ccccc3)n2)cc1,,ClCCl,,CCN(CC)CC,,test
US20140315949A1,COC(=O)c1ccc(C(C)CCOC2CCCCO2)cc1>>COC(=O)c1ccc(C(C)CCO)cc1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20110244481A1,CC(C)(C)[Si](C)(C)Oc1ccc(-c2cnc(N)c(Br)n2)cc1.OB(O)c1cccc2ccccc12>>CC(C)(C)[Si](C)(C)Oc1ccc(-c2cnc(N)c(-c3cccc4ccccc34)n2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],test
US20080004325A1,COC(=O)C(C)Br.Nc1csc(-c2ccccc2)c1>>COC(=O)C(C)Nc1csc(-c2ccccc2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05045557,CN(C)P(=O)(Cl)N(C)C.N#Cc1nc(-c2ccc(Cl)cc2Cl)c[nH]1>>CN(C)P(=O)(N(C)C)n1cc(-c2ccc(Cl)cc2Cl)nc1C#N,,C1CCOC1,,O,[H-].[Na+],test
US20090247550A1,CC(O)(CNC(=O)c1nc(-c2ccc(Cl)cc2)c(Br)nc1C(F)(F)F)C1CC1.[O-]CC1CC1>>CC(O)(CNC(=O)c1nc(-c2ccc(Cl)cc2)c(OCC2CC2)nc1C(F)(F)F)C1CC1,,CS(C)=O,,,,test
US20080221176A1,BrCc1ccccn1.CN(Cc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1>>CCCCN(Cc1ccccn1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04757081,CC(C(=O)CC(=O)c1ccccc1Cl)C(=O)c1ccccc1Cl.Nc1ccccc1Cl>>Cc1c(-c2ccccc2Cl)n(-c2ccccc2Cl)c(-c2ccccc2Cl)cc1=O,,ClC(Cl)Cl,,Cc1ccccc1C,,test
US20130261119A1,CN1C(=O)NC(N)C1=O.Clc1nc(Cl)nc(Cl)n1>>CN1C(=O)NC(Nc2nc(Cl)nc(Cl)n2)C1=O,,CC#N,,O=C([O-])O.[Na+],,test
US20110070317A1,CC(C(=O)Nc1c[nH]c2ncc(Br)c(F)c12)c1ccccc1.CC(C)(C)OC(=O)N[C@@H]1CCCNC1>>CC(C(=O)Nc1c[nH]c2ncc(Br)c(N3CCC[C@@H](NC(=O)OC(C)(C)C)C3)c12)c1ccccc1,,CCC(C)O,,,,test
US06127360,C1CNCCNC1.ClCc1ccc2ccccc2n1>>c1ccc2nc(CN3CCCNCC3)ccc2c1,,CCO,,CCN(CC)CC,Cl,test
US20140228360A1,CN(C)C=O.ClC[C@@H]1CO1.Cn1cnc2ccc(-c3cccc(O)c3)cc21>>Cn1cnc2ccc(-c3cccc(NC[C@H]4CO4)c3)cc21,,O,,[H-].[Na+],,test
US20100240702A1,CCC[C@@H](CC(=O)OCC)n1c(=O)n(Cc2cc(Br)cc3[nH]c(=O)sc23)c2ccccc21>>CCC[C@@H](CC(=O)O)n1c(=O)n(Cc2cc(Br)cc3[nH]c(=O)sc23)c2ccccc21,,C1COCCO1,O,Cl,[Li+].[OH-],test
US20100239576A1,COc1cc2nccc(Oc3ccc(NC(=O)c4c(C)n(C[C@@H](C)OC(=O)[C@H](C)NC(=O)OCc5ccccc5)n(-c5ccccc5)c4=O)cc3F)c2cc1OC>>COc1cc2nccc(Oc3ccc(NC(=O)c4c(C)n(C[C@@H](C)OC(=O)[C@H](C)N)n(-c5ccccc5)c4=O)cc3F)c2cc1OC,[Pd],CCOC(C)=O,CO,,,test
US20110071150A1,CCn1nc(-c2cccnc2)nc1-c1ccc([N+](=O)[O-])c(C)c1.O=Cc1c(Cl)cccc1Cl>>CCn1nc(-c2cccnc2)nc1-c1ccc([N+](=O)[O-])c(CC(O)c2c(Cl)cccc2Cl)c1,,CS(C)=O,,C1CCC2=NCCCN2CC1,,test
US04988496,CC1(SCC(=O)O)CCCO1>>CC1(SCCO)CCCO1,,C1CCOC1,,O,,test
US20040234464A1,CC(C)(C)CO.Cc1ccccc1.O=C(O)CC(=O)O>>CC(C)(C)COC(=O)CC(=O)OCC(C)(C)C,,Cc1ccccc1,,O,O=S(=O)(O)O,test
US20080261969A1,CCOC(=O)c1[nH]ccc1N.O=C1CCCC(=O)C1.O=Cc1ccc(Sc2nc3cc(F)c(F)cc3[nH]2)o1>>CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CCC1)C2c1ccc(Sc2nc3cc(F)c(F)cc3[nH]2)o1,,CCO,,,,test
US05814653,CCO.CCOC(=O)C1CCC(=O)CC1.NNc1ccc(OCc2ccccc2)cc1>>CCC1CC(C(=O)O)Cc2c1[nH]c1ccc(OCc3ccccc3)cc21,,CCO,,Cl,c1ccncc1,test
US20070078122A1,C1CCC2=NCCCN2CC1.C1CCOC1.CN(C)S(N)(=O)=O.O=C(n1ccnc1)n1ccnc1>>CN(C)S(=O)(=O)c1cc2ccccc2[nH]1,,C1CCOC1,,,,test
US20090181942A1,COc1cccc(C(O)c2cc(Cl)ccc2N)c1OC.O=C(O)CC(S)C(=O)O>>COc1cccc(C(SC(CC(=O)O)C(=O)O)c2cc(Cl)ccc2N)c1OC,,CC(=O)O,Cl,[Na+].[OH-],,test
US06391904B1,CC(=O)CCc1cccc(O)c1.CCOC(=O)C(CCBr)NC(=O)OCc1ccccc1.NNC1=NCCN1>>CC(CCc1cccc(OCC[C@H](NC(=O)OCc2ccccc2)C(=O)O)c1)=NNC1=NCCN1,,CO,,Br,,test
US04666510,CCC(=O)C1=C(O)CC(c2c(C)cc(C)cc2C)CC1=O.O=S(=O)(O)Cl>>CCC(=O)C1=C(O)CC(c2c(C)cc(C)c(S(=O)(=O)Cl)c2C)CC1=O,,ClC(Cl)Cl,,,,test
US20080090801A1,CCNc1nc(C)c2cc(CCC(=O)O)c(=O)n(C3CCCC3)c2n1.CNC>>CCNc1nc(C)c2cc(CCC(=O)N(C)C)c(=O)n(C3CCCC3)c2n1,,CN(C)C=O,,CCN(CC)CC,,test
US20050203089A1,COc1ccc(Cl)cc1[C@]1(F)C(=O)N(COC(=O)Cc2nnnn2COCC[Si](C)(C)C)c2cc(C(F)(F)F)ccc21>>COc1ccc(Cl)cc1[C@]1(F)C(=O)N(COC(=O)Cc2nnn[nH]2)c2cc(C(F)(F)F)ccc21,,CC#N,O,,,test
US20100210619A1,CCCNCC1CC1.Cc1cc(S(=O)(=O)NCCC(=O)OC(C)(C)C)ccc1NC(=O)c1cc(Cl)ncn1>>CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(S(=O)(=O)NCCC(=O)OC(C)(C)C)cc2C)ncn1,,CCO,,CC(C)NC(C)C,,test
US20050090498A1,CCOC(=O)CCc1cc(N)ccc1OC.CS(=O)(=O)Cl>>CCOC(=O)CCc1cc(NS(C)(=O)=O)ccc1OC,,ClCCl,,c1ccncc1,,test
US20030036558A1,CCO.CCOC(=O)COc1cc(Cl)ccc1C(=O)NCc1ccc(Br)cc1F>>COc1ccc(C(=O)NCc2ccc(Br)cc2F)c(OCC(=O)O)c1,,CCOC(C)=O,,Cl,[Na+].[OH-],test
US20130096118A1,Cc1c(NC(=O)OCc2ccccc2)cccc1-c1cnc(C(N)=O)c2[nH]c3ccc(N4CCOCC4)cc3c12>>Cc1c(N)cccc1-c1cnc(C(N)=O)c2[nH]c3ccc(N4CCOCC4)cc3c12,[Pd],C1CCOC1,CO,,,test
US05677297,BrCCc1ccccc1.COP(=O)(CC(=O)OC(C)(C)C)OC>>COP(=O)(OC)C(CCc1ccccc1)C(=O)OC(C)(C)C,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20030087908A1,CI.Fc1ccc(Nc2ncnc(Cl)n2)cc1Cl>>CN1C=NC(Nc2ccc(F)c(Cl)c2)=NC1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20150141400A1,CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2cc(CN3CC[C@@H](O[Si](C)(C)C(C)(C)C)C3)c(Br)cc2c1=O>>CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2cc(CN3CC[C@@H](O)C3)c(Br)cc2c1=O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140163024A1,Nc1ccccc1C(F)(F)F.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>O=[N+]([O-])c1ccc(S(=O)(=O)Nc2ccccc2C(F)(F)F)cc1,,ClCCl,,c1ccncc1,,test
US20040157886A1,Fc1ccc(CC2CCNCC2)cc1.O=C(CCl)Nc1ccc2[nH]cnc2c1>>O=C(CN1CCC(Cc2ccc(F)cc2)CC1)Nc1ccc2[nH]cnc2c1,,CCOCC,,,,test
US06054587,CC(C)CBr.Cc1c(NC(=O)c2ccco2)cccc1[N+](=O)[O-]>>Cc1c(N(CC(C)C)C(=O)c2ccco2)cccc1[N+](=O)[O-],,CS(C)=O,,[K+].[OH-],,test
US20100063101A1,O=C(O)C(C1CCCC1)n1c(-c2ccc(Cl)cc2)nc2cc(F)c(F)cc21>>OCC(C1CCCC1)n1c(-c2ccc(Cl)cc2)nc2cc(F)c(F)cc21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06177440B1,COC(=O)c1cccc2c1c1c(O)cccc1n2Cc1ccccc1C.[NH4+]>>Cc1ccccc1Cn1c2cccc(O)c2c2c(C(N)=O)cccc21,,C1CCOC1,CCOC(C)=O,Cl,,test
US20110105495A1,CCOC(=O)CC(=O)c1ccc(Br)s1.O=Cc1cccc(F)c1>>CCOC(=O)C(=Cc1cccc(F)c1)C(=O)c1ccc(Br)s1,,c1ccccc1,,C1CCNCC1,CC(=O)O,test
US07115754B2,CI.CON=C1C[C@@H](CO)N(C(=O)c2ccc(-c3ccccc3)cc2)C1>>COC[C@@H]1CC(=NOC)CN1C(=O)c1ccc(-c2ccccc2)cc1,,C1CCOC1,,[H-].[Na+],,test
US05274100,CC(Oc1ccc(Oc2ncc(Cl)cc2[N+](=O)[O-])cc1)C(=O)O>>CC(Oc1ccc(Oc2ncc(Cl)cc2N)cc1)C(=O)O,[Ni],C1COCCO1,,,,test
US20130244966A1,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)NCCN.O=C(Nc1ccn([C@@H]2CS[C@H](COC(=O)Oc3ccc([N+](=O)[O-])cc3)O2)c(=O)n1)OCC(Cl)(Cl)Cl>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)NCCNC(=O)OC[C@@H]1O[C@H](n2ccc(NC(=O)OCC(Cl)(Cl)Cl)nc2=O)CS1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150065705A1,CC(C)(C)C(=O)OC(=O)C(C)(C)C.CC(C)(C)OC(=O)N1CC[C@@](O)(c2ccc(F)cc2)[C@H](O)C1>>CC(C)(C)OC(=O)N1CC[C@@](O)(c2ccc(F)cc2)[C@H](OC(=O)C(C)(C)C)C1,CN(C)c1ccncc1,CCOC(C)=O,,CCN(CC)CC,ClCCl,test
US20090240052A1,BrCCc1ccccc1.COC(=O)c1ccc(O)cc1NC(=O)c1ccccc1>>COC(=O)c1ccc(OCCc2ccccc2)cc1NC(=O)c1ccccc1,,CCOC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20150225386A1,O=C(NC(=S)NC1(C(F)(F)CO)c2cc(Br)ccc2OCC12CC2)c1ccccc1>>NC(=S)NC1(C(F)(F)CO)c2cc(Br)ccc2OCC12CC2,,CO,,CN,,test
US20100075994A1,CCOC(=O)C#CCOC.NC1=NC[C@@H](COc2ccc(C3C4CCCC3CCC4)cc2)O1>>COCc1cc(=O)nc2n1C[C@@H](COc1ccc(C3C4CCCC3CCC4)cc1)O2,,ClC(Cl)Cl,,,,test
US04284631,CCOCCON=C(C(=O)OCC)c1csc(N)n1.O=CO>>CCOCCON=C(C(=O)OCC)c1csc(NC=O)n1,,O=CO,,CC(=O)OC(C)=O,,test
US20100048636A1,COC(C)(CO[C@@H](c1cccc(Cl)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1)OC>>CC(=O)CO[C@@H](c1cccc(Cl)c1)[C@@H]1CCCNC1,,CC#N,,Cl,,test
US20080001120A1,O=C(O)c1ccc([N+](=O)[O-])cc1.O=[N+]([O-])c1ccc(O)cc1>>O=C(Oc1ccc([N+](=O)[O-])cc1)c1ccc([N+](=O)[O-])cc1,CN(C)c1ccncc1,C1CCOC1,CCN(CC)CC,,,test
US06747024B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccc2c(c1)CCN2>>COC(=O)c1ccc2c(c1)CCN2C(=O)OC(C)(C)C,,CCCCCCC,ClCCl,CCN(CC)CC,,test
US20140206661A1,COc1cc(=O)n(C)c2ccccc12.O=C1CCC(=O)N1Br>>COc1c(Br)c(=O)n(C)c2ccccc12,,C1CCOC1,,,,test
US20100016279A1,FC(F)(F)c1nnc2ccc(Cl)nn12.OC1CNC1>>OC1CN(c2ccc3nnc(C(F)(F)F)n3n2)C1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,Cl,test
US20090270412A1,CC(=CBr)c1ccc(Cl)c(Cl)c1.CC1c2[nH]c3ccc(Cl)cc3c2CCN1C>>CC(=Cn1c2c(c3cc(Cl)ccc31)CCN(C)C2C)c1ccc(Cl)c(Cl)c1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US06548494B1,CC(=O)OCc1ccc2c3c1ccn3C(=O)CNC2>>Cc1ccc2c3c1ccn3C(=O)CNC2,[Pd],CO,,CC(=O)O,,test
US20040106650A1,CN.O=C(O)C1CC(=O)N(c2ccc(OCc3ccc(F)cc3)nc2)C1>>CNC(=O)C1CC(=O)N(c2ccc(OCc3ccc(F)cc3)nc2)C1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20120230951A1,COC(=O)N[C@H]1CCc2ccn3c2C1C(=O)C[C@H](c1nc(-c2ccc(-c4ncc(-c5cnc([C@@H]6CC(F)(F)CN6C(=O)OC(C)(C)C)[nH]5)cn4)cc2)c[nH]1)C3.Cl>>COC(=O)N[C@H]1CCc2ccn3c2C1C(=O)C[C@H](c1nc(-c2ccc(-c4ncc(-c5cnc([C@@H]6CC(F)(F)CN6)[nH]5)cn4)cc2)c[nH]1)C3.Cl,,CCO,,C1COCCO1,,test
US20100317687A1,CC1(C)OB(c2ccc3nc(C(=O)c4ccccc4)cn3c2)OC1(C)C.Ic1ccccn1>>O=C(c1ccccc1)c1cn2cc(-c3ccccn3)ccc2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20070281943A1,CCCC[Sn](CCCC)(CCCC)c1cnc(N(C(=O)OC(C)(C)C)c2ccc(N3CCN(C)CC3)cc2)c2nccn12.CN(C)C=O.NC(=O)c1csc(Br)c1>>CN1CCN(c2ccc(Nc3ncc(-c4cc(C(N)=O)cs4)n4ccnc34)cc2)CC1.N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US20030220332A1,COC(=O)c1ccc(OC)c(O)c1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>COC(=O)c1ccc(OC)c(OCC(F)(F)F)c1,,CN(C)C=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20060287343A1,CC(C)(C)OC(=O)N1CCN(Cc2ccc(Br)cc2)CC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(C)(C)OC(=O)N1CCN(Cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CC(=O)[O-].[K+],,test
US20130005727A1,C1COCCN1.COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1O[C@@H]1C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1>>COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1O[C@@H]1C[C@@H](C(=O)N2CCOCC2)N(C(=O)OC(C)(C)C)C1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020132796A1,COC(=O)Cc1ccc(C#Cc2ccc(CO)c(C(C)C)c2)cc1.O=C1CCC(=O)N1Br>>COC(=O)Cc1ccc(C#Cc2ccc(CBr)c(C(C)C)c2)cc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140018393A1,CC(C)(C)OC(=O)N1CCC(CCN(C(=O)C(F)(F)F)[C@@H]2C[C@H]2c2ccccc2)CC1>>O=C(N(CCC1CCNCC1)[C@@H]1C[C@H]1c1ccccc1)C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US04326069,CCCCOC(=O)/C=C\C(=O)O.CN(C)CCCN>>CCCCOC(=O)[C@H](CC(=O)O)NCCCN(C)C,,CCN(CC)CC,,,,test
US20130324542A1,CCOC(OCC)OCC.O=CC(=O)c1ccccc1>>CCOC(OCC)C(=O)c1ccccc1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100292207A1,N#Cc1cc(C(O)c2cc(F)cc(F)c2)ccc1F>>N#Cc1cc(Cc2cc(F)cc(F)c2)ccc1F,,CC#N,CCOC(C)=O,C[Si](C)(C)Cl,[I-].[Na+],test
US20040058903A1,CN(C(=O)OC(C)(C)C)c1nc(CCOc2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2)cs1>>CNc1nc(CCOc2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2)cs1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20100190688A1,CC(C(=O)NC(CCCCNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N1CSCC1C(=O)NC1CCCc2ccccc21)N(C)C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CNC(C)C(=O)NC(CCCCNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N1CSCC1C(=O)NC1CCCc2ccccc21.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20100273850A1,CC(C)(C)OC(=O)Cc1ccc(-n2ncc3cc(C(=O)NCCc4ccc(Cl)cc4)ccc32)c(C#N)c1>>N#Cc1cc(CC(=O)O)ccc1-n1ncc2cc(C(=O)NCCc3ccc(Cl)cc3)ccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110144105A1,CC(C)C=C(c1cccc(Cl)c1)c1cc2cccnc2[nH]1>>CC(C)CC(c1cccc(Cl)c1)c1cc2cccnc2[nH]1,O=[Pt]=O,C1CCOC1,,,,test
US20050222412A1,Nc1nccc(-c2ccccn2)n1.O=[N+]([O-])[O-]>>O=c1nc(-c2ccccn2)cc[nH]1,,O=S(=O)(O)O,,[Na+].[OH-],,test
US06124313,Cc1cccc(N)c1COc1cccn2c(C=O)c(C)nc12.O=C(Cl)OCCCl>>Cc1cccc(NC(=O)OCCCl)c1COc1cccn2c(C=O)c(C)nc12,,ClCCl,,,,test
US03952031,CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@@H](OCCCCl)C[C@]4(C)[C@H]3C(=O)C[C@]12C.OCCO>>CC1([C@H]2CC[C@H]3[C@@H]4CC[C@H]5C[C@H](O)[C@@H](OCCCCl)C[C@]5(C)[C@H]4C(=O)C[C@@]32C)OCCO1,,CCOCC,c1ccccc1,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20120010247A1,CC(=O)c1cc2cc(O)ccc2o1.CC(C)(C)[Si](C)(C)Cl>>CC(=O)c1cc2cc(O[Si](C)(C)C(C)(C)C)ccc2o1,,CN(C)C=O,,c1c[nH]cn1,,test
US20050096337A1,CCOC(=O)C(C)(C)Oc1ccc(OCc2ccc(-c3ccc(OC(F)(F)F)cc3)nc2C)cc1C>>Cc1cc(OCc2ccc(-c3ccc(OC(F)(F)F)cc3)nc2C)ccc1OC(C)(C)C(=O)O,,C1CCOC1,CCO,[Na+].[OH-],,test
US20040229844A1,COC(=O)C[C@H]1CCCc2c1[nH]c1c(S(C)(=O)=O)cc(F)cc21.C[C@@H](O)c1ccc(C(F)(F)F)cc1>>COC(=O)C[C@H]1CCCc2c1n([C@@H](C)c1ccc(C(F)(F)F)cc1)c1c(S(C)(=O)=O)cc(F)cc21,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130245049A1,CCOC(=O)CC(=O)OCC.Cc1ccc(C(=O)c2cc3c(nc2N)CCCC3)cc1>>CCOC(=O)c1c(O)nc2nc3c(cc2c1-c1ccc(C)cc1)CCCC3,,CCO,,C,C[O-].[Na+],test
US20100160324A1,CC(=O)Cl.Nc1c[nH]nc1-c1ccccn1>>CC(=O)Nc1c[nH]nc1-c1ccccn1,,C1CCOC1,,CCN(CC)CC,,test
US20160159808A1,CB1OB(C)OB(C)O1.CC(C)(O)C(NC(=O)c1cnn2ccc(Cl)nc12)c1ccc(OC(F)(F)F)c(F)c1>>Cc1ccn2ncc(C(=O)NC(c3ccc(OC(F)(F)F)c(F)c3)C(C)(C)O)c2n1,,CCC(C)(C)O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090227588A1,O=C(Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)nc1)c1cccc(O)c1.O=C1CCCN1CCO>>O=C(Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)nc1)c1cccc(OCCN2CCCC2=O)c1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130317001A1,O=C(O)c1cc(F)c(F)c(Cl)c1F.OCC12CC3CC(CC(C3)C1)C2>>O=C(O)c1cc(F)c(OCC23CC4CC(CC(C4)C2)C3)c(Cl)c1F,,CCOC(C)=O,CS(C)=O,CC(C)(C)[O-].[K+],,test
US20110200557A1,CCCCN(C(=O)c1ccccc1Cl)c1nnc(-c2ccc(C(=O)OC)cc2)s1>>CCCCN(C(=O)c1ccccc1Cl)c1nnc(-c2ccc(C(=O)O)cc2)s1,,Cl,,,,test
US05639782,COC1=C[C@]23C[C@H](C[C@H](c4ccc5c(c4)OCO5)[C@H]2C)OC3=CC1=O>>CC1C(c2ccc3c(c2)OCO3)CC2CC13C=C(O)C(=O)C=C3O2,,O,,O=S(=O)(O)O,,test
US20020107278A1,CC(C)(C)OC(=O)N1CCc2[nH]c3ccccc3c2CC1.O=C1CCO1>>CC(C)(C)OC(=O)N1CCc2c(n(CCC(=O)O)c3ccccc23)CC1,,CN(C)C=O,O,[H-].[Na+],O=C([O-])[O-].[K+].[K+],test
US05686482,COc1cc(Cl)c([N+](=O)[O-])cc1C(=O)O.C[S-]>>COc1cc(SC)c([N+](=O)[O-])cc1C(=O)O,,CS(C)=O,,Cl,,test
US05296492,CC1(C)C=C(n2ccc(C(O)CCO[Si](C)(C)C(C)(C)C)cc2=O)c2cc(C#N)ccc2O1.S=C(Cl)Oc1ccccc1>>CC1(C)C=C(n2ccc(C(CCO[Si](C)(C)C(C)(C)C)OC(=S)Oc3ccccc3)cc2=O)c2cc(C#N)ccc2O1,CN(C)c1ccncc1,CC#N,,O=C([O-])O.[Na+],,test
US03947434,Cc1cc(Nc2ccccc2)c2c(ccc3nc[nH]c32)n1.Cc1ccc(N)cc1[N+](=O)[O-].Cl>>Cc1cc(Nc2ccc(C)c([N+](=O)[O-])c2)c2c(ccc3nc[nH]c32)n1.Cl,,CCO,,,,test
US20060287522A1,NCc1cccnc1.O=C(c1ccc(-c2ccccc2)cc1)N1Cc2ccc(C(=O)C(Cl)(Cl)Cl)n2Cc2ccccc21>>O=C(NCc1cccnc1)c1ccc2n1Cc1ccccc1N(C(=O)c1ccc(-c3ccccc3)cc1)C2,,C1COCCO1,,O,,test
US20090221608A1,Cc1c[nH]c2ncc(Br)cc12.O=S(=O)(Cl)c1ccc(Br)cc1>>Cc1cn(S(=O)(=O)c2ccccc2)c2ncc(Br)cc12,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US09283555B2,Cc1ccc(C(=O)Nc2ccccc2C(C)(C)C)cc1.ClP(Cl)(Cl)(Cl)Cl>>Cc1ccc(C(Cl)=Nc2ccccc2C(C)(C)C)cc1,,c1ccccc1,,,,test
US20140349970A1,Cc1ccc(S(=O)(=O)n2c(-c3cccc(CC(=O)NCCN4CCN(C)CC4)c3)cc3c4c(cnc32)cnn4C)cc1>>CN1CCN(CCNC(=O)Cc2cccc(-c3cc4c(ncc5cnn(C)c54)[nH]3)c2)CC1,,CO,,[Na+].[OH-],,test
US20120289526A1,COc1ccc(C)c(Oc2ccc([N+](=O)[O-])cc2)c1>>COc1ccc(C)c(Oc2ccc(N)cc2)c1,[Pd],CO,,,,test
US20040092737A1,COC(=O)c1cnc(S)c(N)c1.Clc1nccnc1Cl>>COC(=O)c1cnc2c(c1)Nc1nccnc1S2,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20150344407A1,CCOC(=O)C=C1c2ccccc2CCc2ccccc21>>OCC=C1c2ccccc2CCc2ccccc21,,CCCCCC,,,,test
US06184225B2,COC(=O)Oc1cc(Nc2ncnc3cc(O)ccc23)c(F)cc1C>>Cc1cc(F)c(Nc2ncnc3cc(O)ccc23)cc1O,,CO,,Cl,[Na+].[OH-],test
US20110136763A1,CCOC(=O)CC1OB(O)c2cc(OC3CCCCO3)cc(C)c21>>CCOC(=O)CC1OB(O)c2cc(O)cc(C)c21,,C1CCOC1,,Cl,,test
US20050267149A1,CC(C)(C)OC(=O)Nc1cccc(CNC(=O)c2ccc(-c3ccccc3)cc2)c1>>Nc1cccc(CNC(=O)c2ccc(-c3ccccc3)cc2)c1,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20130116243A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)-n3c(nnc3C3CC3)CO4)cc2)CCC1>>NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)-n3c(nnc3C3CC3)CO4)cc2)CCC1,,O=C(O)C(F)(F)F,,,,test
US20150165063A1,BrCc1ccccc1.CC(C)(C)OC(=O)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21>>CC(C)(C)OC(=O)N1C[C@@H](CCl)c2c1cc(OCc1ccccc1)c1ccccc21,,CCOC(C)=O,CN(C)C=O,[I-].[K+],,test
US04150139,CS(=O)c1nnc2n1C=Cc1ccccc1C2>>O=c1[nH]nc2n1C=Cc1ccccc1C2,,O,,O=P(O)(O)O,,test
US20150025252A1,CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C.O=C(O)CC(=O)O>>CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C.O=C([O-])CC(=O)[O-],,CO,ClCCl,,,test
US20150183802A1,CC(C)COc1ncc(-n2cc(C#N)c3cc4c(NS(=O)(=O)C5CC5)noc4cc32)cc1Cl.O>>CC(C)COc1ncc(-n2cc(C(N)=O)c3cc4c(NS(=O)(=O)C5CC5)noc4cc32)cc1Cl,,CO,O,[Na+].[OH-],,test
US04328244,Nc1cccc(S(=O)(=O)O)c1.O=[N+]([O-])c1ccc(CBr)cc1>>O=[N+]([O-])c1ccc(CNc2cccc(S(=O)(=O)O)c2)cc1,,CC#N,O,Cl,CC(=O)[O-].[Na+],test
US06780853B1,C1CCOC1.C[C@@]12CCC[C@H]1[C@@H]1CC[C@H]3CC(=O)CC[C@]3(C)[C@H]1CC2.[Li]C>>C#CCO[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@](C)(O)CC[C@]4(C)[C@H]3CC[C@]12C,,ClCCl,,,,test
US05891895,COCOc1cccnc1C(=O)c1ccc(F)c(Br)c1.[C-]#N>>COCOc1cccnc1C(=O)c1ccc(C#N)c(Br)c1,,CS(C)=O,,O,,test
US20100056490A1,CC(C)(C)c1cccc(CN2C(=O)O[C@H]3[C@H](Cc4cc(F)c(N)c(OCC(F)(F)F)c4)CS(=O)(=O)C[C@@H]32)c1.O=C(Cl)CCl>>CC(C)(C)c1cccc(CN2C(=O)O[C@H]3[C@H](Cc4cc(F)c(NC(=O)CCl)c(OCC(F)(F)F)c4)CS(=O)(=O)C[C@@H]32)c1,,Cc1ccccc1,,,,test
US06169107A,CCOC(=O)c1cc2c(COC3CCCCO3)cccc2n1C>>CCOC(=O)c1cc2c(CO)cccc2n1C,,C1CCOC1,,Cl,,test
US20130317218A1,CC(=O)Nc1ccc(C(=O)O)cc1.NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1N>>CC(=O)Nc1ccc(C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)cc1,,C1CCOC1,c1ccncc1,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20070225267A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@@H]1N[C@@H]([C@H](OCc2ccccc2)[C@H](Cc2cc(F)cc(F)c2)N(Cc2ccccc2)Cc2ccccc2)CO[C@H]1OCC(C)(C)C>>C[C@H]1[C@H](OCC(C)(C)C)OC[C@H]([C@@H](OCc2ccccc2)[C@H](Cc2cc(F)cc(F)c2)N(Cc2ccccc2)Cc2ccccc2)N1C(=O)OC(C)(C)C,,ClCCCl,,CCN(C(C)C)C(C)C,,test
US20100249124A1,CI.Cn1c(=O)oc2cc(C(=O)Cc3ccc(Br)cc3Cl)ccc21>>CC(C(=O)c1ccc2c(c1)oc(=O)n2C)c1ccc(Br)cc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20070010556A1,COC(=O)c1cc(Cc2ccccc2)sc1N.O=C=NC(=O)C(Cl)(Cl)Cl>>COC(=O)c1cc(Cc2ccccc2)sc1NC(=O)NC(=O)C(Cl)(Cl)Cl,,C1CCOC1,,,,test
US04948795,O=C(O)C1CSC(c2cccnc2)N1.c1cnc(N2CCNCC2)nc1>>O=C(C1CSC(c2cccnc2)N1)N1CCN(c2ncccn2)CC1,,CCN(CC)CC,CN(C)C=O,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20150259341A1,CC1(C)OB(c2ccnn2-c2ccc(F)cc2)OC1(C)C.Fc1ccc(-c2cnc3ccc(Br)cn23)cc1>>Fc1ccc(-c2cnc3ccc(-c4ccnn4-c4ccc(F)cc4)cn23)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US20150051171A1,Cc1cccc(-n2nnn(C)c2=O)c1CBr.Oc1ccn(-c2ccccc2Br)n1>>Cc1cccc(-n2nnn(C)c2=O)c1COc1ccn(-c2ccccc2Br)n1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US05585378,O=C1Cc2cc([N+](=O)[O-])ccc2N1CCN1CCN(Cc2ccccc2)CC1>>Nc1ccc2c(c1)CC(=O)N2CCN1CCN(Cc2ccccc2)CC1,[Pd],CCO,,,,test
US20030073847A1,Cc1cc(OCC=C(Cl)Cl)cc(Cl)c1O.OCCCOc1ccc(C(F)(F)F)cn1>>Cc1cc(OCC=C(Cl)Cl)cc(Cl)c1OCCCOc1ccc(C(F)(F)F)cn1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120316124A1,Cc1cc(C(=O)C=P(c2ccccc2)(c2ccccc2)c2ccccc2)ccc1Br.O=C(c1cc(Cl)cc(Cl)c1)C(F)(F)F>>Cc1cc(C(=O)C=C(c2cc(Cl)cc(Cl)c2)C(F)(F)F)ccc1Br,,Cc1ccccc1,,,,test
US20140206673A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.O=C(Cl)C1CC1>>CC(C)(C)OC(=O)N1CCC(=O)C(C(=O)C2CC2)C1,,Cc1ccccc1,,CC(C)[N-]C(C)C.[Li+],,test
US20130237535A1,CC1(C)OB(c2ccc(S(=O)(=O)N3CCC4(CC3)CN(C3CC3)C(=O)CO4)cc2)OC1(C)C.Fc1cnc2cc(Br)ccc2c1>>O=C1COC2(CCN(S(=O)(=O)c3ccc(-c4ccc5cc(F)cnc5c4)cc3)CC2)CN1C1CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US04670447,N#CN1CCC(c2nn(-c3ccc(C(F)(F)F)cc3)c3ccccc23)CC1>>FC(F)(F)c1ccc(-n2nc(C3CCNCC3)c3ccccc32)cc1,,O,,O=S(=O)(O)O,[Na+].[OH-],test
US20110039866A1,Nc1ccc(Cl)cc1.O=C(NC(O)C(=O)c1cccc2ccccc12)c1ccc(Br)cn1>>O=C(NC(Nc1ccc(Cl)cc1)C(=O)c1cccc2ccccc12)c1ccc(Br)cn1,,C1CCOC1,ClC(Cl)Cl,ClP(Cl)(Cl)(Cl)Cl,,test
US20110212998A1,CCOC(=O)c1cc(C)nc(C=C(C)C)c1>>CCOC(=O)c1cc(C)nc(CC(C)C)c1,[Pd],C1CCOC1,CO,,,test
US20090023725A1,Fc1cc(Br)ccc1[Zn]I.O=C(Cl)c1ccccn1>>O=C(c1ccccn1)c1ccc(Br)cc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,CCOC(C)=O,Cl,[Cl-].[NH4+],test
US20150057451A1,CC(C)(C)[Si](C)(C)Cl.O=C1Nc2ccccc2C1=O>>CC(C)(C)[Si](C)(C)N1C(=O)C(=O)c2ccccc21,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US04110450,CCOC(=O)CC.CCOC(=O)c1cc(N(C)C)ncn1>>CCOC(=O)C(C)C(=O)c1cc(N(C)C)ncn1,,COCCOC,,[H-].[Na+],,test
US20160272632A1,CCOP(=O)(CC#N)OCC.O=C1CCOCC1F>>N#CC=C1CCOCC1F,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05399578,CCCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)C1(C(=O)OCc2ccccc2)CCCCC1>>CCCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)C1(C(=O)O)CCCCC1,[Pd],C1COCCO1,,CCOC(C)=O,,test
US20110218192A1,CNO.N#C/N=C1\CC(c2ccc(OC(F)(F)F)cc2)Oc2ccc(Br)cc21>>CN1OC2(CC(c3ccc(OC(F)(F)F)cc3)Oc3ccc(Br)cc32)N=C1N,,CO,,Cl,C[O-].[Na+],test
US20100240702A1,C=C(C)n1c(=O)[nH]c2ccc(C)cc21.Cc1c(C)n(C)c2c(CO)cc(Cl)cc12>>C=C(C)n1c(=O)n(Cc2cc(Cl)cc3c(C)c(C)n(C)c23)c2ccc(C)cc21,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080153852A1,CN(C)Cc1ccc(-c2ccccc2C(Oc2cc(Cl)nc(N)n2)C(F)(F)F)o1.N[C@@H](Cc1ccc(B(O)O)cc1)C(=O)O>>CN(C)Cc1ccc(-c2ccccc2C(Oc2cc(-c3ccc(C[C@H](N)C(=O)O)cc3)nc(N)n2)C(F)(F)F)o1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US20150361078A1,BrCc1ccccc1.CC1CCC(=O)N1>>CC1CCC(=O)N1Cc1ccccc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20110015175A1,CI.COc1cc(NC(N)=S)ccc1-n1cnc(Cl)c1>>COc1cc(NC(=N)SC)ccc1-n1cnc(Cl)c1.I,,CCO,,,,test
US08318928B2,CC(C)(C)COc1c(/C=C/c2nc3sccn3c2C(=O)O)cccc1OC(F)F.NCc1cccc(C(F)(F)F)c1>>CC(C)(C)COc1c(/C=C/c2nc3sccn3c2C(=O)NCc2cccc(C(F)(F)F)c2)cccc1OC(F)F,CN(C)c1ccncc1,C1CCOC1,CN(C)C=O,CCN=C=NCCCN(C)C,Cl,test
US20130079328A1,CC(C)(C)OC(=O)c1ccc(-c2cccc(F)c2)cn1>>O=C(O)c1ccc(-c2cccc(F)c2)cn1,,ClCCl,O,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],test
US20120283216A1,CCC(Oc1ccc2ccc(O)cc2c1)C(=O)OC.CCI>>CCOc1ccc2ccc(OC(CC)C(=O)OC)cc2c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05438052,BrP(Br)Br.Cc1cc(=O)n2nc(CO)nc2[nH]1>>Cc1cc(O)n2nc(CBr)nc2n1,,CN(C)C=O,,,,test
US20100093757A1,CC(C)(C)[Si](C)(C)Cl.COC(=O)CCCCO>>COC(=O)CCCCO[Si](C)(C)C(C)(C)C,,ClCCl,,c1c[nH]cn1,,test
US20090215821A1,CCOC(=O)C1(C(Cl)(c2ccc(C(F)(F)F)cc2)c2ccc(C(F)(F)F)cc2)CCN(C(=O)OC(C)(C)C)CC1>>CCOC(=O)C1(C(Cl)(c2ccc(C(F)(F)F)cc2)c2ccc(C(F)(F)F)cc2)CCNCC1,,Cc1ccccc1,ClCCl,O=C(O)C(F)(F)F,,test
US04316985,CC(=O)O[C@@H]1c2ccccc2[C@H]1OC(C)=O.COC(=O)C1CCC2=C(C1)C(=O)C=CC2=O>>COC(=O)C1CCC2=C(C1)C(=O)c1cc3ccccc3cc1C2=O,,Cc1ccccc1C,,,,test
US05912246,Cc1cccn2cc(CCl)nc12.Clc1ccc(N2CCNCC2)c(Cl)c1>>Cc1cccn2cc(CN3CCN(c4ccc(Cl)cc4Cl)CC3)nc12,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20110040115A1,COc1ccc(-c2ccc3cc(O)ccc3c2)cc1C12CC3CC(CC(C3)C1)C2.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1ccc(-c2ccc3cc(OS(=O)(=O)C(F)(F)F)ccc3c2)cc1C12CC3CC(CC(C3)C1)C2,,CCO,ClCCl,CCN(CC)CC,O,test
US04593037,COc1cccc(C2CCCNC2)c1.O=C(CCCCl)c1ccc(F)cc1>>COc1cccc(C2CCCN(CCCC(=O)c3ccc(F)cc3)C2)c1,,CC(=O)CC(C)C,,O=C([O-])[O-].[K+].[K+],,test
US04367234,COC(Cl)Cl.COc1ccc(Cl)c(C)c1>>COc1ccc(Cl)c(C)c1C=O,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20120040953A1,CC(C)OC(=O)N1CCC(O[C@H](C)C(=O)O)C1.N>>CC(C)OC(=O)N1CCC(O[C@H](C)C(N)=O)C1,,C1CCOC1,C1COCCO1,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20160175289A1,CC(F)(CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)COS(=O)(=O)C(F)(F)F.CC(N)Cc1c[nH]c2ccc(F)cc12>>CC(Cc1c[nH]c2ccc(F)cc12)NCC(C)(F)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20130059834A1,CC(C)(C)OC(=O)NC1CCC(=O)CC1.CC(C)(C)S(N)=O>>CC(C)(C)OC(=O)NC1CCC(=NS(=O)C(C)(C)C)CC1,,C1CCOC1,,,,test
US05504189,C[C@@H](O)[C@H](NC(=O)OCc1ccccc1)C(=O)O.O=C(CBr)c1ccccc1>>C[C@@H](O)[C@H](NC(=O)OCc1ccccc1)C(=O)OCC(=O)c1ccccc1,,CC(C)O,CCOC(C)=O,CCN(CC)CC,O,test
US20160200730A1,CC(C)(Cn1nc(-c2ccc(Oc3c(F)c(F)cc(F)c3F)cc2F)c2c(N)ncnc21)NC(=O)OC(C)(C)C.Cl>>CC(C)(N)Cn1nc(-c2ccc(Oc3c(F)c(F)cc(F)c3F)cc2F)c2c(N)ncnc21.Cl,,ClCCl,,CCOC(C)=O,,test
US20060257987A1,CCc1ccc(O[C@@H](C)CCOc2ccc(CCC(=O)OC)c(C)c2)c(-c2cccs2)c1>>CCc1ccc(O[C@@H](C)CCOc2ccc(CCC(=O)O)c(C)c2)c(-c2cccs2)c1,,CO,,,,test
US20090082343A1,COC(=O)c1ccccc1S.N#Cc1nccs1>>O=c1nc(-c2nccs2)sc2ccccc12,,Cc1ccccc1,,CCN(CC)CC,,test
US20060178418A1,COc1ccc(C(=O)Oc2ccc([N+](=O)[O-])cc2)c2c3cc(Cl)ccc3n(Cc3ccc(F)cc3)c12.Nc1c(Cl)cncc1Cl>>COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2c3cc(Cl)ccc3n(Cc3ccc(F)cc3)c12,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20110183997A1,CCc1cc2c(cn1)cc(-c1cc(N/C(N)=N/O)ccc1C)c(=O)n2C.O=C(O)c1ccccn1>>CCc1cc2c(cn1)cc(-c1cc(Nc3noc(-c4ccccn4)n3)ccc1C)c(=O)n2C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140296253A1,ClCCCBr.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>ClCCCN1CCN(C(c2ccccc2)c2ccccc2)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040254159A1,CC(=O)Nc1ccc(C=O)cc1.O=[N+]([O-])O>>CC(=O)Nc1ccc(C=O)cc1[N+](=O)[O-],,O,,,,test
US20070054891A1,OC(c1ccc(Cl)cc1)c1ccccc1Cl.OC1CN(C(c2ccccc2)c2ccccc2)C1>>Clc1ccc(C(OC2CN(C(c3ccccc3)c3ccccc3)C2)c2ccccc2Cl)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US03996344,C[C@H](N)Cc1ccccc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(Cc1ccccc1)NC(=O)C(F)(F)F,,c1ccccc1,,,,test
US03932416,Cc1ccc2c(Cl)cc(C(=O)O)nc2c1C.Nc1nnn[nH]1>>Cc1ccc2c(Cl)cc(C(=O)Nc3nnn[nH]3)nc2c1C,,CN(C)C=O,,,,test
US20070254867A1,CC(=O)NC(N)=S.O=C(CCl)CCl>>CC(=O)Nc1nc(CCl)cs1,,CC(C)=O,CCOC(C)=O,,,test
US20040132727A1,COc1cc2nccc(Oc3ccc(N)c(C)c3C)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OCCc1cccc(C(F)(F)F)c1>>COc1cc2nccc(Oc3ccc(NC(=O)OCCc4cccc(C(F)(F)F)c4)c(C)c3C)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20100029678A1,Cc1ncc2c(c1O)COC2c1ccc(Cl)cc1.O=C(OCCCCC(CO[N+](=O)[O-])O[N+](=O)[O-])Oc1ccc([N+](=O)[O-])cc1>>Cc1ncc2c(c1OC(=O)OCCCCC(CO[N+](=O)[O-])O[N+](=O)[O-])COC2c1ccc(Cl)cc1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140275080A1,CC1(C)CC(C(N)=O)C1.Cn1cc(-c2cc(Oc3ccc(N)nc3)ncn2)cn1.O=C(Cl)C(=O)Cl>>Cn1cc(-c2cc(Oc3ccc(NC(=O)NC(=O)C4CC(C)(C)C4)nc3)ncn2)cn1,,C1COCCO1,ClCCl,c1ccncc1,,test
US20090163533A1,CCCn1nc(C(=O)OCC)cc1CC1CCOCC1>>CCCn1nc(C(=O)O)cc1CC1CCOCC1,,CO,O,CC(=O)O,[Li+].[OH-],test
US20120029002A1,COC(=O)OC(=O)OC.Nc1nc(-n2nc(Nc3ccccc3F)c3ccccc32)nc(N)c1N>>COC(=O)Nc1c(N)nc(-n2nc(Nc3ccccc3F)c3ccccc32)nc1N.O=CO,,CC(C)O,,,,test
US20130059856A1,CC(C)(Cc1c(F)ccc(F)c1F)c1ncc(C=O)n1-c1ccc(F)cc1.O=C(O)c1cnc(-c2c(F)ccc(F)c2F)n1-c1ccc(F)cc1>>CC(C)(Cc1c(F)ccc(F)c1F)c1ncc(C(=O)O)n1-c1ccc(F)cc1,,CC(C)(C)O,O,CC=C(C)C,[Na+].[O-]Cl,test
US20080070907A1,C[C@@H](CO)Nc1c([N+](=O)[O-])cnc2ccccc12>>C[C@@H](CO)Nc1c(N)cnc2ccccc12,[Pt],Cc1ccccc1,,,,test
US20120277224A1,CC1(C)OC(=O)C(C(=O)c2ccc3c(c2)OCCO3)C(=O)O1.CCO>>CCOC(=O)CC(=O)c1ccc2c(c1)OCCO2,,CCO,,,,test
US20050070592A1,Cc1c(-c2ccccc2)n(Cc2ccccc2)c2cccc(-c3ccc(OCC#N)cc3)c12.[N-]=[N+]=[N-]>>Cc1c(-c2ccccc2)n(Cc2ccccc2)c2cccc(-c3ccc(OCc4nnn[nH]4)cc3)c12,,CN(C)C=O,,[Cl-].[NH4+],,test
US20060030613A1,CC(C)(C)c1ccc(C=O)cc1.NCCCc1ccccc1>>CC(C)(C)c1ccc(CNCCCc2ccccc2)cc1,,CO,,Cl,[BH4-].[Na+],test
US04767755,CCOC(=O)c1ccc(C(=O)CBr)cc1.Cc1ccc(N)nc1>>CCOC(=O)c1ccc(-c2cn3cc(C)ccc3n2)cc1,,CCO,,O=C([O-])O.[Na+],,test
US04725600,C1=CCNCC1.COc1ccc(-c2cc(=Nc3c(C)cc(C)cc3C)n(C)c(Cl)n2)cc1OC>>COc1ccc(-c2cc(=Nc3c(C)cc(C)cc3C)n(C)c(N3CC=CCC3)n2)cc1OC,,CCO,,,,test
US20090023753A1,O=C(NC(=O)c1ccccc1)Nc1cc(CNc2ncsc2C(=O)Nc2ccc3c(c2)OC(F)(F)O3)ccn1>>NC(=O)Nc1cc(CNc2ncsc2C(=O)Nc2ccc3c(c2)OC(F)(F)O3)ccn1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20060160857A1,CN(C)C=O.Cc1cccc(N)n1.Cc1nc(C(=O)O)c(Br)s1>>Cc1cccc(NC(=O)c2cc(C)sc2Br)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20100311966A1,CC(C)(C)OC(=O)N1Cc2ccc(N)cc2C1.CCOC(=O)[C@@H]1C[C@H]1C(=O)O>>CCOC(=O)[C@@H]1C[C@H]1C(=O)Nc1ccc2c(c1)CC(N)C2,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20040063935A1,C1COCCN1.CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.Cl>>Cl.O=C(C1CCNCC1)N1CCOCC1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20160075711A1,COC(=O)C1CCC(F)(CCC2c3c(F)cccc3-c3cncn32)CC1>>OCC1CCC(F)(CCC2c3c(F)cccc3-c3cncn32)CC1,,CCCCCC,,CCO,,test
US04282212,CCCCCC(=O)N=C=O.N#CC1CN1>>CCCCCC(=O)NC(=O)N1CC1C#N,,CCOCC,,Cc1ccccc1,,test
US05608056,C=CCOC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]1CCCO.CS(=O)(=O)Cl>>C=CCOC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]1CCCOS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20050131014A1,N#Cc1cnc2c(C(F)(F)F)cccc2c1-c1cccc(N)c1.OO>>NC(=O)c1cnc2c(C(F)(F)F)cccc2c1-c1cccc(N)c1,,CCO,,Cl,[Na+].[OH-],test
US07067540B2,Cc1cc(O)c(Br)c(=O)n1Cc1cccc(F)c1>>Cc1cc(O)cc(=O)n1Cc1cccc(F)c1,,ClCCl,,CCN(CC)CC,,test
US20100204208A1,CC(C)Oc1ccc([N+](=O)[O-])cc1N(C)C(C)C>>CC(C)Oc1ccc(N)cc1N(C)C(C)C,[Pd],CCO,,,,test
US06495562B1,CC(C)(C)OC(=O)N1CCc2cc(C=Cc3ccc4cc(C#N)ccc4c3)ccc2C1>>N#Cc1ccc2cc(C=Cc3ccc4c(c3)CCNC4)ccc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100249118A1,CC(C)[Si](C(C)C)(C(C)C)n1cc(C=O)c2cccnc21.COc1cccc(S(=O)(=O)Nc2ccc(F)cc2F)c1>>COc1cccc(S(=O)(=O)Nc2ccc(F)c(C(O)c3cn([Si](C(C)C)(C(C)C)C(C)C)c4ncccc34)c2F)c1,,C1CCOC1,,O,CC(C)[N-]C(C)C.[Li+],test
US20040014767A1,CC(C)(C)OC(=O)N1CCN(c2cncc(Cl)n2)CC1>>Clc1cncc(N2CCNCC2)n1,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20010041172A1,C[C@H]1CC[C@H]2[C@H](C)[C@H](OCc3ccc(C(=O)O)cc3)O[C@@H]3O[C@@]4(C)CC[C@H]1[C@]23OO4>>C[C@H]1[C@@H](OCc2ccc(C(=O)O)cc2)O[C@@H]2OC3(C)CC[C@H]4[C@H](C)CC[C@@H]1[C@@]24OO3,CN(C)c1ccncc1,ClC(Cl)Cl,,On1nnc2ccccc21,,test
US20010036944A1,COc1cc(C=O)cc2c1OCO2.Cc1ccccc1NS(=O)(=O)c1ccccc1>>COc1cc(C(O)c2ccccc2S(=O)(=O)Nc2ccccc2C)cc2c1OCO2,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US06251910B1,CCCSc1nc(NC2CC2c2ccccc2)c2nnn(C3CC(C=CCO)C(O)C3O)c2n1>>CCCSc1nc(NC2CC2c2ccccc2)c2nnn(C3CC(CCCO)C(O)C3O)c2n1,,C1CCOC1,,,,test
US20080269286A1,C=O.Fc1ccc(C2CCNCC2)c(F)c1>>CN1CCC(c2ccc(F)cc2F)CC1,,O,,O=CO,,test
US20160108019A1,CC(C)(C)OC(=O)N1CCC(N)CC1.Cc1c(Br)ccc(F)c1[N+](=O)[O-]>>Cc1c(Br)ccc(N2CCN(C(=O)OC(C)(C)C)CC2)c1[N+](=O)[O-],,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150111877A1,CC(C)(C)[Si](C)(C)OCC1Cc2ncc(N=C(c3ccccc3)c3ccccc3)cc2N(Cc2ccccc2)C1>>CC(C)(C)[Si](C)(C)OCC1Cc2ncc(N)cc2N(Cc2ccccc2)C1,[Pd],CO,,O=C[O-].[NH4+],,test
US20100105900A1,COC(=O)C[C@H](C[N+](C)(C)C)NS(=O)(=O)n1ccnc1.COS(=O)(=O)C(F)(F)F.[Cl-]>>COC(=O)C[C@H](C[N+](C)(C)C)NS(=O)(=O)n1cc[n+](C)c1.O=S(=O)([O-])C(F)(F)F.[Cl-],,ClCCl,,,,test
US20110071126A1,C=CCc1c(C(=O)O)ccc(F)c1F.O=[O+][O-]>>O=C(O)c1ccc(F)c(F)c1CCO,,ClCCl,,[BH4-].[Na+],,test
US06046189,CC(=O)OC(C)=O.COc1ccc(-c2c(Cl)c(CN)nc3sc4c(c23)CCN(Cc2ccccc2)C4)cc1OC>>COc1ccc(-c2c(Cl)c(CNC(C)=O)nc3sc4c(c23)CCN(Cc2ccccc2)C4)cc1OC,,c1ccncc1,,,,test
US20110313165A1,C1=NCCC1.C=CC(=O)Cl.O=[N+]([O-])Cc1ccccc1>>O=C1CCC(c2ccccc2)([N+](=O)[O-])C2CCCN12,,C1COCCO1,,,,test
US20020137689A1,CC(C)[Si](C)(C)OC(CCC1C(=O)N(c2ccc(F)cc2)C1c1ccc(OCCCCC[N+](C)(C)C)cc1)c1ccc(F)cc1.[Br-]>>C[N+](C)(C)CCCCCOc1ccc(C2C(CCC(O)c3ccc(F)cc3)C(=O)N2c2ccc(F)cc2)cc1.[Br-],,CO,,Cl,O=C([O-])O.[Na+],test
US20160046570A1,CC(C)(C)OC(=O)NOC(=O)OC1CCOCC1.CS(=O)(=O)c1ccccc1S(=O)(=O)Cl>>CS(=O)(=O)c1ccccc1S(=O)(=O)NOC(=O)OC1CCOCC1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US04640707,O=[N+]([O-])O.O=c1[nH]c2ccc(F)cc2o1>>O=c1[nH]c2cc([N+](=O)[O-])c(F)cc2o1,,O=S(=O)(O)O,,,,test
US20100179154A1,ClI.Clc1ccc2nc(-c3ccccc3)cn2n1>>Clc1ccc2nc(-c3ccccc3)c(I)n2n1,,ClC(Cl)Cl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US05795887,CC(C)C(C(N)=O)(c1ccccc1)N1C(=O)C(NC(=O)Nc2cccc(C(=O)OC(C)(C)C)c2)N=C(c2ccccc2)c2ccccc21>>CC(C)C(C(N)=O)(c1ccccc1)N1C(=O)C(NC(=O)Nc2cccc(C(=O)O)c2)N=C(c2ccccc2)c2ccccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100130583A1,CN(C)C(=O)[C@]1(CO[Si](C)(C)C(C)(C)C)CC[C@H](c2ccc(OCc3ccccc3F)cc2)N1C(=O)OCc1ccccc1>>CN(C)C(=O)[C@]1(CO[Si](C)(C)C(C)(C)C)CC[C@H](c2ccc(OCc3ccccc3F)cc2)N1,[Pd],CO,,,,test
US20150307507A1,Cc1ncc(-c2cnc(C(=O)OC(C)(C)C)s2)cn1.O=C(O)C(F)(F)F>>Cc1ncc(-c2cnc(C(=O)O)s2)cn1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20150361077A1,CCCCCCOc1ccccc1OCCN.Clc1ncnc2ccccc12>>CCCCCCOc1ccccc1OCCNc1ncnc2ccccc12,,CC(C)O,,,,test
US20150239845A1,O=C(c1ccc(Cl)cc1)c1ccc2[nH]c(=O)cc(CCc3cccc(Cl)c3)c2c1.c1cscn1>>O=c1cc(CCc2cccc(Cl)c2)c2cc(C(O)(c3ccc(Cl)cc3)c3nccs3)ccc2[nH]1,,C1CCOC1,CN(C)P(=O)(N(C)C)N(C)C,[Li]CCCC,,test
US20020028831A1,BrBr.CCOC(=O)c1ccc(-c2ccc(OC)cc2)cc1>>CCOC(=O)c1ccc(-c2ccc(OC)c(Br)c2)cc1,,ClC(Cl)(Cl)Cl,,,,test
US20030153596A1,CS(=O)(=O)Cl.Nc1cccc(CN2C(=O)c3ccccc3C2=O)n1>>CS(=O)(=O)Nc1cccc(CN2C(=O)c3ccccc3C2=O)n1,,ClCCl,,CCN(CC)CC,,test
US20080261941A1,CC(C)OB(OC(C)C)OC(C)C.Cc1cc(Br)cc(Oc2ccc(C(F)(F)F)cn2)c1>>Cc1cc(Oc2ccc(C(F)(F)F)cn2)cc(B(O)O)c1,,Cc1ccccc1,,C1CCOC1,[Li]CCCC,test
US06218431B1,CCCC=Cc1c(C(C)C)nc(C(C)C)c(C(=O)OCC)c1-c1ccccc1C>>CCCC=Cc1c(C(C)C)nc(C(C)C)c(CO)c1-c1ccccc1C,,CCCCCC,CCOC(C)=O,,,test
US20080070935A1,Cc1c[nH]c2c1C(=O)CC(C)(C)C2.Nc1ncc2ccc(F)cc2n1>>Cc1cn(-c2ccc3cnc(N)nc3c2)c2c1C(=O)CC(C)(C)C2,,CN(C)C=O,,[H-].[Na+],,test
US20020037900A1,Brc1ccc(N2CCNCC2)cc1.CC(C)C(CS(=O)(=O)Cl)C(=O)OC(C)(C)C>>CC(C)C(CS(=O)(=O)N1CCN(c2ccc(Br)cc2)CC1)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,Cl,test
US20110039843A1,Nc1cc(OC(F)(F)F)ccc1O.O=C(O)c1ccncc1Cl>>O=C(Nc1cc(OC(F)(F)F)ccc1O)c1ccncc1Cl,,CN(C)C=O,O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US04311651,OC(C(F)(F)F)(C(F)(F)F)C(F)(F)F.[Li]CCCC>>[Li+].[O-]C(C(F)(F)F)(C(F)(F)F)C(F)(F)F,,CCCCCC,,,,test
US20050032786A1,CC(C)(C)OC(=O)CCc1cccc(C#N)n1.COc1ccc(C(=O)O)c(S)c1>>COc1ccc2c(=O)nc(-c3cccc(CCC(=O)OC(C)(C)C)n3)sc2c1,,c1ccncc1,,,,test
US20140235671A1,CCOC(=O)CCCCCCN(c1ccccn1)c1cc(-c2ccc(F)cc2)ccn1.NO>>O=C(CCCCCCN(c1ccccn1)c1cc(-c2ccc(F)cc2)ccn1)NO,,CN(C)C=O,CO,,,test
US20110237791A1,COc1nc(/C(=C/C2CCCC2)c2ccc(SC)cc2)ccc1Cl>>CSc1ccc(/C(=C\C2CCCC2)c2ccc(Cl)c(=O)[nH]2)cc1,,C1COCCO1,,Br,O,test
US20060142543A1,C1CCOC1.CC(=O)O.CC(=O)[O-]>>CC(=O)OC(C)=O.CC(=O)[O-],,C1CCOC1,,,,test
US20140275056A1,CC(C)(C)OC(=O)N1C2CCCC1C(=O)NC2.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)OC(=O)N1C2CCCC1C(=S)NC2,,C1CCOC1,,,,test
US20090275590A1,CC(=O)Cl.Cn1c2c(c3ccc(-n4ccc(-c5ccc(C(F)(F)F)cn5)cc4=O)cc31)CNCC2>>CC(=O)N1CCc2c(c3ccc(-n4ccc(-c5ccc(C(F)(F)F)cn5)cc4=O)cc3n2C)C1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US20140213581A1,COC(=O)c1ccc(C2CC2)cn1>>O=C(O)c1ccc(C2CC2)cn1,,CO,,[K+].[OH-],,test
US03946049,N#Cc1ccc(-c2ccc(Cl)cc2)o1.NO>>NC(=NO)c1ccc(-c2ccc(Cl)cc2)o1,,CCO,,Cl,[K+].[OH-],test
US20070254866A1,CCOC(=O)c1cn(C2CC2)c2c(OC(C)C)c(F)c(F)c(N)c2c1=O>>CC(C)Oc1c(F)c(F)c(N)c2c(=O)c(C(=O)O)cn(C3CC3)c12,,CCO,,Cl,[Na+].[OH-],test
US05849928,O=C(Cl)C(=O)Cl.O=C(O)c1ccc(S(F)(F)(F)(F)F)cc1>>O=C(Cl)c1ccc(S(F)(F)(F)(F)F)cc1,CN(C)C=O,CC(Cl)Cl,ClCCl,,,test
US20140066424A1,COC(=O)c1cc(-c2ccc(OC(F)(F)F)cc2)no1.NN>>NNC(=O)c1cc(-c2ccc(OC(F)(F)F)cc2)no1,,CCO,,O,,test
US20110021534A1,CCOC(Cc1ccc(C(=O)OCc2ccc(OS(C)(=O)=O)cc2)cc1)C(=O)OCC(Cl)(Cl)Cl>>CCOC(Cc1ccc(C(=O)OCc2ccc(OS(C)(=O)=O)cc2)cc1)C(=O)O,[Zn],ClCCl,,CC(=O)O,,test
US20100298323A1,BrCCOCCBr.N[C@@H]1CC[C@@H](CNc2ccc(S(N)(=O)=O)cc2[N+](=O)[O-])CC1>>NS(=O)(=O)c1ccc(NC[C@@H]2CC[C@@H](N3CCOCC3)CC2)c([N+](=O)[O-])c1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US06262074B1,C=O.Cc1ccc(C(=O)O)c2c1NCCC2>>Cc1ccc(C(=O)O)c2c1N(C)CCC2,,CC(=O)O,,[Na+].[OH-],,test
US20050277689A1,COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12.O=S(=O)(O)O>>COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12.O=S(=O)([O-])[O-],,O,,CC(C)=O,,test
US20070244103A1,O=CC=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccccn1>>O=C/C=C/c1ccccn1,,Cc1ccccc1,,,,test
US03998958,CN1CCCC1=N.O=C=Nc1c(Br)cc(Br)cc1Br>>CN1CCCC1=NC(=O)Nc1c(Br)cc(Br)cc1Br,,c1ccccc1,,,,test
US20050277676A1,CC(C)(C)OC(=O)N1CCC(CO)CC1.Nc1ccccc1-c1nc(C2CCCC2)cs1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)N1CCC(COC(=O)Nc2ccccc2-c2nc(C3CCCC3)cs2)CC1,,C1CCOC1,O,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20120065156A1,COC(=O)C(C)(C)N.Cl.O=P(Cl)(Cl)Oc1ccccc1>>COC(=O)C(C)(C)N=[P+]([O-])Oc1ccccc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070208033A1,CCCN(CCC)CCN1CCNCC1.O=C(O)c1ccc(CN(Cc2ncc[nH]2)Cc2ncc[nH]2)cc1>>CCCN(CCC)CCN1CCN(C(=O)c2ccc(CN(Cc3ncc[nH]3)Cc3ncc[nH]3)cc2)CC1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20160083362A1,CCN1CC[C@H](C(=O)O)C1.COC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2CN)ccc2c1OC[C@@H]1C[C@H]21>>CCN1CC[C@H](C(=O)NCc2cc(F)ccc2S(=O)(=O)Nc2ccc3c(c2C(=O)OC)OC[C@@H]2C[C@H]32)C1,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20020193596A1,CC(C)(C)OC(=O)c1cccc(Sc2cccnc2)c1-c1ccccc1>>O=C(O)c1cccc(Sc2cccnc2)c1-c1ccccc1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20050054819A1,CCCC[C@H](NC(=O)OC1(Cc2ccccc2)CCCC1)C(=O)OC.N#CC=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCCC[C@H](NC(=O)OC1(Cc2ccccc2)CCCC1)C(=O)C(C#N)=P(c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)c1ccncc1,C1CCOC1,O,[Li+].[OH-],,test
US20070197571A1,C=CC(C)O.O=Cc1cccc(O)c1>>C=CC(C)Oc1cccc(C=O)c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04997836,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C1CN(C(=O)OCc2ccccc2)CCN1>>COC(=O)C1CN(C(=O)OCc2ccccc2)CCN1C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,O,test
US20090105325A1,Cc1cc(C(F)(F)F)n(C)n1.II>>Cc1nn(C)c(C(F)(F)F)c1I,,O=S(=O)(O)O,,,,test
US06861438B2,CCOC(=O)c1c[nH]c2cc(C=O)sc2c1=O.CI>>CCOC(=O)c1cn(C)c2cc(C=O)sc2c1=O,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20050197340A1,CSc1nc(Cl)cc(Cl)n1.O=CC1CCCC1>>CSc1nc(Cl)c(C(O)C2CCCC2)c(Cl)n1,,C1CCOC1,,[Li],,test
US20050054851A1,CC(C)(C)Cn1c(Cn2[nH]c(=O)c3ccccc3c2=O)cc2cnc(C#N)nc21.CN(C)C=O>>Cn1c(=O)c2ccccc2c(=O)n1Cc1cc2cnc(C#N)nc2n1CC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100105678A1,CO.O=C(O)c1cc([N+](=O)[O-])cnc1Cl>>COc1ncc([N+](=O)[O-])cc1C(=O)O,,CO,,[Na],C[O-].[Na+],test
US20100152168A1,CCOC(=O)n1c(=O)[nH]c2ccccc21.COC(=O)C(Br)c1ccccc1OC>>CCOC(=O)n1c(=O)n(C(C(=O)OC)c2ccccc2OC)c2ccccc21,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],[Cl-].[NH4+],test
US04101522,CC(C)(C)N=NC(C)(C#N)CCCO.O=C(Cl)c1ccc2c(c1)C(=O)OC2=O>>CC(C)(C)N=NC(C)(C#N)CCCOC(=O)c1ccc2c(c1)C(=O)OC2=O,,CCOCC,,c1ccncc1,,test
US20050090534A1,CC(C)c1nc(Cl)sc1C=O.CCOC(=O)CP(=O)(OCC)OCC.c1ccc2[nH]cnc2c1>>CCOC(=O)/C=C/c1sc(-n2cnc3ccccc32)nc1C(C)C,,CN(C)C=O,O,[H-].[Na+],,test
US20110166128A1,CCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCC)OC(=O)OCI.Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1>>CCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCC)OC(=O)OC[N+]1(C)CCN(C2=Nc3ccccc3Nc3sc(C)cc32)CC1.[I-],,CCOC(C)=O,CCOCC,,,test
US04880926,CC1COc2c(ccc(F)c2F)N1>>CC1COc2c(ccc(F)c2F)N1,,ClC(Cl)Cl,,Cl,O=C([O-])O.[Na+],test
US05686445,CCc1cc(NC(=O)c2cccnc2)ccc1C(=O)O>>O=C(O)c1ccc(NC(=O)c2cccnc2)cc1,,CO,,[Na+].[OH-],,test
US20070225372A1,CC(=O)N1[C@@H](Cc2cc(F)cc(F)c2)[C@@H]([C@H]2CC[C@@H](O)CN2C(=O)OC(C)(C)C)OC1(C)C.CC(C)CCBr>>CC(=O)N1[C@@H](Cc2cc(F)cc(F)c2)[C@@H]([C@H]2CC[C@@H](OCCC(C)C)CN2C(=O)OC(C)(C)C)OC1(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20060229336A1,CC(C)(C)C(=O)Cl.Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2cccc(O)c2)CCNCC1>>Cc1nc2ccccc2n1C1C[C@@H]2CC[C@H](C1)N2CCC1(c2cccc(O)c2)CCN(C(=O)C(C)(C)C)CC1,,ClCCl,,Br,CCN(CC)CC,test
US20130345123A1,COC(=O)[C@@H]1CCC[C@@H]2SCC[C@H](NC(=O)[C@H](CC[C@H](CCC(=O)OC(C)(C)C)C(=O)N[C@H]3CCS[C@H]4CCC[C@@H](C(=O)OC)N4C3=O)Cc3ccccc3)C(=O)N21>>COC(=O)[C@@H]1CCC[C@@H]2SCC[C@H](NC(=O)[C@H](CC[C@H](CCC(=O)O)C(=O)N[C@H]3CCS[C@H]4CCC[C@@H](C(=O)OC)N4C3=O)Cc3ccccc3)C(=O)N21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160185752A1,Brc1cccnc1.NC(=O)c1ccccc1B(O)O>>NC(=O)c1ccccc1-c1cccnc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100286152A1,NNc1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(O)C(c1ccc2c(c1)OCCO2)N1CCN2CCC[C@@H]2C1>>O=C(NNc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(c1ccc2c(c1)OCCO2)N1CCN2CCC[C@@H]2C1,,CN(C)C=O,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US05047548,CSCCNC(=O)CC(O)(Cn1cncn1)c1ccc(Cl)cc1Cl.O=C(OO)c1cccc(Cl)c1>>CS(=O)CCNC(=O)CC(O)(Cn1cncn1)c1ccc(Cl)cc1Cl,,CC(C)O,ClCCl,,,test
US20060258725A1,CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CO.Cc1cc(F)ccc1[N+](=O)[O-]>>Cc1cc(OCc2c(-c3c(Cl)cccc3Cl)noc2C(C)C)ccc1[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],,test
US20110105530A1,NCc1ccccc1.O=C(O)c1ccnc(Cl)c1>>O=C(NCc1ccccc1)c1ccnc(Cl)c1,,ClCCl,O=S(Cl)Cl,CCN(CC)CC,,test
US20120094972A1,Brc1cn[nH]c1.Cc1c(-c2ccccn2)nc2cc(F)ccc2c1N1CC(C)(C)c2ncc(B(O)O)cc21>>Cc1c(-c2ccccn2)nc2cc(F)ccc2c1N1CC(C)(C)c2ncc(-c3cn[nH]c3)cc21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US20140275071A1,O=C1CCCCC1.OCCO>>C1CCC2(CC1)OCCO2,,CCOC(C)=O,,II,,test
US20100197711A1,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1cccc(Br)n1>>Cc1ccc(S(=O)(=O)Nc2cccc(Br)n2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20130165423A1,CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)O.C[C@@H]1CN(c2ccc3ncn([C@H](C)c4ccc(Cl)cc4F)c3c2)CCN1>>C[C@@H]1CN(c2ccc3ncn([C@H](C)c4ccc(Cl)cc4F)c3c2)CCN1C(=O)[C@H]1CCCN1,,CCOC(C)=O,ClCCl,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150133451A1,CCOC(=O)c1coc(-c2ccnc(N(CC(F)F)C(=O)OC(C)(C)C)c2)n1>>CC(C)(C)OC(=O)N(CC(F)F)c1cc(-c2nc(C(=O)O)co2)ccn1,,CO,,Cl,[Na+].[OH-],test
US05994563,O=C(Cl)c1ccccc1.O=Cc1ccc(O)c([N+](=O)[O-])c1>>O=Cc1ccc(OC(=O)c2ccccc2)c([N+](=O)[O-])c1,,ClCCl,,CCN(CC)CC,,test
US04251443,Nc1ccc([N+](=O)[O-])cc1C(=O)c1ccccc1F.O=C(O)CNC(=O)OCc1ccccc1>>O=C(CNC(=O)OCc1ccccc1)Nc1ccc([N+](=O)[O-])cc1C(=O)c1ccccc1F,,C1CCOC1,,O=S(Cl)Cl,,test
US20140094474A1,CC(C)=Cn1ccc(C(=O)O)n1.C[C@H](N)Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1>>CC(C)=Cn1ccc(C(=O)N[C@@H](C)Cn2ccc(-c3ccc(C#N)c(Cl)c3)n2)n1,,ClCCl,,,,test
US06028032,CC(C)(C(=O)Nc1cc(Cl)cc(Cl)c1)N1COC(C=O)=C(c2ccccc2)C1=O.NO>>C=C1OC(=NO)C(c2ccccc2)C(=O)N1C(C)(C)C(=O)Nc1cc(Cl)cc(Cl)c1,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20160009691A1,CN(C)CCN.COc1ncc(Cc2cnc(Cl)nc2)cc1-c1cccc(Cl)c1>>COc1ncc(Cc2cnc(NCCN(C)C)nc2)cc1-c1cccc(Cl)c1,,CC#N,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20080108661A1,O=C(NC[C@@H](O)CN1CCC(Oc2ccc(Cl)c(Cl)c2)CC1)c1sc(=O)[nH]c1C(F)(F)F.O=S(=O)(O)c1ccccc1>>O=C(NC[C@@H](O)CN1CCC(Oc2ccc(Cl)c(Cl)c2)CC1)c1sc(=O)[nH]c1C(F)(F)F.O=S(=O)(O)c1ccccc1,,CO,,,,test
US05112817,Nc1cccc2ncccc12.O=C(Cl)CCCl>>O=C(CCCl)Nc1cccc2ncccc12,,ClCCl,,CCN(CC)CC,[Na+].[OH-],test
US20100048568A1,Cc1c[nH]c2ccc(F)cc12.NOS(=O)(=O)O>>Cc1cn(N)c2ccc(F)cc12,,CN(C)C=O,,[H-].[Na+],,test
US20030176418A1,CCCOC1CCNCC1.O=c1ccc2ccccc2n1CCCCl>>CCCOC1CCN(CCCn2c(=O)ccc3ccccc32)CC1,,CCOC(C)=O,O,CC#N,O=C([O-])[O-].[K+].[K+],test
US20100093731A1,COc1cc(Nc2nc(Cl)nc(OC(C)C)n2)ccc1-n1cnc(C)c1.Oc1ccccc1C(F)(F)F>>COc1cc(Nc2nc(Oc3ccccc3C(F)(F)F)nc(OC(C)C)n2)ccc1-n1cnc(C)c1,,CCOC(C)=O,,,,test
US04482552,O=C1c2ccccc2C(=O)N1CC1CO1.Oc1cccc(CN2CCCCC2)c1>>O=C1c2ccccc2C(=O)N1CC(O)COc1cccc(CN2CCCCC2)c1,,ClC(Cl)Cl,,,,test
US20060247179A1,CC(=O)OC[C@H]1O[C@H](OC(=N)C(Cl)(Cl)Cl)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.NC(=NC(=O)OCc1ccccc1)c1ccc(CCc2coc3cccc(O)c23)cc1>>CC(=O)OC[C@H]1O[C@@H](Oc2cccc3occ(CCc4ccc(C(N)=NC(=O)OCc5ccccc5)cc4)c23)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,ClCCl,,O=C([O-])O.[Na+],,test
US05925673,CC(O)=S.COc1ccc2cc(C(C)CO)ccc2c1>>COc1ccc2cc(C(C)COC(C)=S)ccc2c1,,C1CCOC1,CCOC(C)=O,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060228387A1,CC1=CNC(=O)C2C(C)CCC12.CCCCCCCCI>>CCCCCCCCN1C[C@@H](C)[C@H]2CC[C@H](C)[C@H]2C1=O,,C1CCOC1,,,,test
US20050004164A1,Br[Mg]c1cccc2ccccc12.CCOC(=O)C(C#N)=Cc1ccc(OC)cc1OC>>CCOC(=O)C(C#N)C(c1ccc(OC)cc1OC)c1cccc2ccccc12,,C1CCOC1,,,,test
US04602014,O.O=c1c2c[nH]c3c(c-2nn1-c1ccccc1)CSCC3>>O=c1c2c[nH]c3c(c-2nn1-c1ccccc1)CS(=O)CC3,,CO,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20150197509A1,CCNCC(=O)NCc1cccc(-c2ccc(C(F)(F)F)cc2)c1.O=S(=O)(Cl)c1ccc(F)cc1>>CCN(CC(=O)NCc1cccc(-c2ccc(C(F)(F)F)cc2)c1)S(=O)(=O)c1ccc(F)cc1,,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US20080255162A1,COC(=O)c1cc(N)cn1C.COCCn1c(=O)c(-c2cccc(OCc3ccccc3)c2)cc2c(C)nc(S(C)=O)nc21>>COCCn1c(=O)c(-c2cccc(OCc3ccccc3)c2)cc2c(C)nc(Nc3cc(C(=O)OC)n(C)c3)nc21,,CC#N,CN(C)C=O,CCN(CC)CC,Cl,test
US20160200725A1,CC(C)(C)OC(=O)N1CCN(CCCI)CC1.COc1cc(OC)c(Cl)c(-c2cc3cnc(SC)nc3[nH]c2=O)c1>>COc1cc(OC)c(Cl)c(-c2cc3cnc(SC)nc3n(CCCN3CCN(C(=O)OC(C)(C)C)CC3)c2=O)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20150309041A1,CCOCC.C[Si](C)(C)C=[N+]=[N-].ClCCl.O=C1CCCCc2ccc(OCc3ccccc3)cc21>>O=C1CCCCCCC1.O=C1CCCCc2ccc(OCc3ccccc3)cc2C1,,ClCCl,,FB(F)F,,test
US20040072853A1,NO.O=C(Cc1cccc(Cl)n1)c1ccc(F)cc1>>ON=C(Cc1cccc(Cl)n1)c1ccc(F)cc1,,CO,,Cl,[Na+].[OH-],test
US20130184241A1,Nc1cccnc1Cl.OB(O)c1ccccc1>>Nc1cccnc1-c1ccccc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20030018026A1,Cc1cc(C(=O)N2Cc3ccc(C(=O)N4CCNCC4)n3Cc3ccccc32)ccc1-c1ccccc1C(F)(F)F.OC[C@@H]1CO1>>Cc1cc(C(=O)N2Cc3ccc(C(=O)N4CCN(C[C@H](O)CO)CC4)n3Cc3ccccc32)ccc1-c1ccccc1C(F)(F)F,,CO,,CCN(C(C)C)C(C)C,Cl,test
US20120196894A1,C=CC1=COCCC1.C=CC=O>>O=C[C@@H]1CCC=C2CCCO[C@@H]21,,ClCCl,,O,,test
US20100144756A1,COc1ccc(Cn2cc(-c3nc(Nc4ccccn4)sc3C#N)cn2)cc1>>N#Cc1sc(Nc2ccccn2)nc1-c1cn[nH]c1,,O=C(O)C(F)(F)F,,O,O=C([O-])[O-].[Na+].[Na+],test
US06358973B1,COc1cccc(C(c2ccccc2)C(C)[N+](=O)[O-])c1>>COc1cccc(C(CN)c2ccccc2)c1,[Pd],CO,,O=C[O-].[NH4+],,test
US05057528,CS(=O)(=O)Cl.Nc1ccc(OCC2CCN(C(=O)OCc3ccccc3)CC2)cc1>>CS(=O)(=O)Nc1ccc(OCC2CCN(C(=O)OCc3ccccc3)CC2)cc1,,c1ccncc1,,,,test
US20070026339A1,CC(C)(O)C1CC2C=CC1C2.O=C(O)CCl>>CC(C)(OCC(=O)O)C1CC2C=CC1C2,,Cc1ccccc1,,O,[Li]CCCC,test
US20110118245A1,CC(CF)(CF)c1cc(NC(=O)Oc2ccccc2)no1.COc1cc2ncnc(Oc3cccc(N)c3)c2cc1OC>>COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(CF)CF)on4)c3)c2cc1OC,CN(C)c1ccncc1,C1CCOC1,,,,test
US20080262041A1,C=O.N#Cc1cc(CN2CCC(C3(c4ccc(F)cc4)CCNCC3)C2=O)c2cc(F)ccc2c1>>CN1CCC(c2ccc(F)cc2)(C2CCN(Cc3cc(C#N)cc4ccc(F)cc34)C2=O)CC1,,CC#N,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20120190724A1,ClCC1CO1.O=c1c2ccccc2oc2cc(O)cc(O)c12>>O=c1c2ccccc2oc2cc(OCC3CO3)cc(O)c12,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20020006936A1,NO.O=C1CCCc2cc(OCCn3ccnc3)ccc21>>ON=C1CCCc2cc(OCCn3ccnc3)ccc21,,O,c1ccncc1,Cl,,test
US20150065705A1,CN(C)C=O.FC(F)(F)c1cc2cc(Br)ccc2o1>>O=Cc1ccc2oc(C(F)(F)F)cc2c1,,C1CCOC1,CCOC(C)=O,[Li]CCCC,[Cl-].[NH4+],test
US20160130237A1,CCN1CCN(c2ccc(Nc3cc(N(C)C(=O)Nc4c(Cl)c(OC)cc(OC)c4Cl)ncn3)c([N+](=O)[O-])c2)CC1>>CCN1CCN(c2ccc(Nc3cc(N(C)C(=O)Nc4c(Cl)c(OC)cc(OC)c4Cl)ncn3)c(N)c2)CC1,[Ni],C1CCOC1,CO,,,test
US20110021537A1,CCCCN=C=O.O=C(NCC(=O)N1CCNCC1)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1>>CCCCNC(=O)N1CCN(C(=O)CNC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)NC3CCC3)n(-c3ccccc3)n2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080249175A1,O=[N+]([O-])c1ccc(F)cc1.Oc1ccc(OC(F)(F)F)cc1>>O=[N+]([O-])c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1,,O,,CC(=O)N(C)C,O=C([O-])[O-].[K+].[K+],test
US07074801B1,CCCC[Sn](CCCC)(CCCC)c1cccs1.Clc1ncnc2ccc(Br)cc12>>Brc1ccc2ncnc(-c3cccs3)c2c1,,Cc1ccccc1,,,,test
US06011028,N#CCC1CCCCC1=NO.O=S(=O)(Cl)c1ccccc1>>N#CCC1CCCCC(=O)N1,,CC(C)=O,O,[Na+].[OH-],,test
US20110144126A1,COc1ccc(COc2cccc(OC)c2-c2cc(Nc3cnc(Br)cn3)n[nH]2)cc1>>COc1cccc(O)c1-c1cc(Nc2cnc(Br)cn2)n[nH]1,,CO,,,,test
US04566900,Cc1ccc(C(=O)CCc2ccc(N)cc2)cc1>>Cc1ccc(C(O)CCc2ccc(N)cc2)cc1,[Pd],C1CCOC1,,[H][H],,test
US20070275962A1,NC(=O)c1c(NC(=O)Oc2ccccc2)sc2c1CCOC2.NC1CCCC1>>NC(=O)c1c(NC(=O)NC2CCCC2)sc2c1CCOC2,,C1CCOC1,,[Na+].[OH-],,test
US04229449,CN1CC(C(Oc2ccccc2[N+](=O)[O-])c2ccccc2)OCC1=O>>CN1CC(C(Oc2ccccc2N)c2ccccc2)OCC1=O,[Pd],CN(C)C=O,,,,test
US20140329825A1,N#Cc1ccc(F)nc1.NO>>NC(=NO)c1ccc(F)nc1,,CCO,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20020183307A1,CCCCC1(CCCC)CN(c2ccc(OC)cc2)c2cc(N(C)C)ccc2S(=O)(=O)C1>>CCCCC1(CCCC)CN(c2ccc(O)cc2)c2cc(N(C)C)ccc2S(=O)(=O)C1,,ClCCl,,BrB(Br)Br,O,test
US20020169188A1,CS(=O)(=O)Cl.O=S(=O)(Oc1cccc2oc(CCO)cc12)C(F)(F)F>>CS(=O)(=O)OCCc1cc2c(OS(=O)(=O)C(F)(F)F)cccc2o1,,ClCCl,,CCN(CC)CC,,test
US06645774B1,NC[C@@H]1CC[C@@H](CNS(=O)(=O)c2ccc3ccccc3c2)CC1.O=C(O)C1CCc2ccccc2C1>>O=C(NC[C@@H]1CC[C@@H](CNS(=O)(=O)c2ccc3ccccc3c2)CC1)C1CCc2ccccc2C1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US04061697,COP(=O)(OC)c1ccc([N+](=O)[O-])cc1[N+](=O)[O-]>>COP(=O)(OC)c1ccc(N)cc1N,[Ni],CO,,,,test
US20160176868A1,CON(C)C(=O)C1CCC(F)(F)CC1>>O=CC1CCC(F)(F)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05574049,Cc1cc2c(cc1Br)C(O)CC(C)(C)O2>>Cc1cc2c(cc1Br)C=CC(C)(C)O2,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04380638,CN(CC(N)=S)C(=O)Oc1ccccc1.O=C(CCl)CCl>>CN(Cc1nc(CCl)cs1)C(=O)Oc1ccccc1,,CCO,,c1ccncc1,,test
US20120088774A1,CN1CC(=O)N2[C@H](c3ccc4c(c3)OCO4)c3[nH]c4ccccc4c3C[C@@H]2C1=O.O=[Si]=O>>CN1CC(=O)N2[C@H](c3ccc4c(c3)OCO4)c3[nH]c4ccccc4c3C[C@@H]2C1=O.O=[Si]=O,,ClCCl,,,,test
US20150232428A1,Cc1cc(-c2ccccc2)cc([N+](=O)[O-])c1.O=C1CCC(=O)N1Br>>O=[N+]([O-])c1cc(CBr)cc(-c2ccccc2)c1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20100035865A1,C=O.CC(C)S(=O)(=O)N[C@@H]1CNCC[C@H]1c1ccc(-c2ccccc2)cc1>>CC(C)S(=O)(=O)N[C@@H]1CN(C)CC[C@H]1c1ccc(-c2ccccc2)cc1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04072685,CC(C)I.COc1ccc(C2CCCNC2)cc1OC>>COc1ccc(C2CCCN(C(C)C)C2)cc1OC,O=[Ag],CC(C)=O,,,,test
US20150342185A1,CCOC(=O)CC(=O)OCC.CSC(C)C/C=C/C(C)=O>>CCOC(=O)C1C(=O)CC(=O)CC1CC(C)SC,,CCO,,[Na],,test
US05442064,CI.COC(=O)[C@@H]1CC[C@@H](NC(=O)N2CCN(c3ccc(C#N)cc3)CC2)CC1>>COC(=O)[C@@H]1CC[C@@H](N(C)C(=O)N2CCN(c3ccc(C#N)cc3)CC2)CC1,,CS(C)=O,O,CCOC(C)=O,CC(C)(C)[O-].[K+],test
US20150203511A1,CCOC(=O)C(C)C(=O)c1ccc(OC)c(C)c1.CNN>>COc1ccc(-c2nn(C)c(O)c2C)cc1C,,Cc1ccccc1,,,,test
US20110245224A1,Cc1ncc(-c2noc3c(Cl)c(N4C[C@H](C)O[C@H](C)C4)c(C=O)nc23)s1.O=C1CC(=O)NC(=O)N1>>Cc1ncc(-c2noc3c(Cl)c4c(nc23)CC2(C(=O)NC(=O)NC2=O)[C@H]2[C@H](C)O[C@H](C)CN42)s1,,CC(C)O,,,,test
US20160237044A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2ccc(-c3ccc(S(=O)(=O)NC4CCN(C(=O)OC(C)(C)C)CC4)cc3C(F)(F)F)cc2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)CC1.Cl>>Cl.NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2ccc(-c3ccc(S(=O)(=O)NC4CCNCC4)cc3C(F)(F)F)cc2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)CC1,,C1COCCO1,,,,test
US04735959,CC(c1ccccc1N1CCCCC1)C(C(N)=O)c1ccc(C(=O)OCc2ccccc2)cc1>>CC(c1ccccc1N1CCCCC1)C(C(N)=O)c1ccc(C(=O)O)cc1,[Pd],CCO,,[H][H],,test
US20040048883A1,Fc1ccc(Nc2ncnc3cc4c(cc23)OCCCSCCCO4)cc1Cl.O=S([O-])OO>>O=S1(=O)CCCOc2cc3ncnc(Nc4ccc(F)c(Cl)c4)c3cc2OCCC1,,CO,,O,,test
US04933355,CCOC(=O)C(=O)c1csc(N)n1.O=C=Nc1ccc(Cl)cc1>>CCOC(=O)C(=O)c1csc(NC(=O)Nc2ccc(Cl)cc2)n1,,CN(C)C=O,,,,test
US20070299072A1,CC(C)(C)c1ccc(CC=O)cc1.COc1ccc(CCNC(=O)C2(N)CCN(C(=O)OC(C)(C)C)CC2)cc1>>COc1ccc(CCN2C(=O)C3(CCN(C(=O)OC(C)(C)C)CC3)NC2Cc2ccc(C(C)(C)C)cc2)cc1,,CCOC(C)=O,CO,O=C([O-])[O-].[K+].[K+],,test
US20110034490A1,CN(Cc1ccccc1)c1nc(=O)[nH]cc1F.O=C(Cl)c1cccs1>>CN(Cc1ccccc1)c1nc(=O)n(C(=O)c2cccs2)cc1F,,ClCCl,,CCN(CC)CC,,test
US20090111809A1,CC(=O)OC(C)=O.OCc1c(Cl)cccc1Cl>>CC(=O)OCc1c(Cl)cccc1Cl,CN(C)c1ccncc1,CCN(CC)CC,,ClCCl,,test
US04336408,CCO.CCOC(=O)C1(C(=O)OCC)COC(C)(C)OC1>>CCOC(=O)C1COC(C)(C)OC1,,CS(C)=O,,O,[Cl-].[Na+],test
US04923869,CNc1ccc(C2=NNC(=O)CC2C)cc1N.O=C(O)c1ccncc1>>CC1CC(=O)NN=C1c1ccc2c(c1)nc(-c1ccncc1)n2C,,CC(=O)O,,C1CCOC1,,test
US04875922,Brc1cncnc1.CC(C)C=O>>CC(C)C(O)c1cncnc1,,C1CCOC1,,O,[Li]CCCC,test
US20120157452A1,Cc1ccc(S(=O)(=O)n2nc(O)cc2N)cc1.O=CC(C=O)[N+](=O)[O-]>>Cc1ccc(S(=O)(=O)n2nc(O)c3cc([N+](=O)[O-])cnc32)cc1,,CC(=O)O,O,[Na],,test
US20140256734A1,CC(C)(C)OC(=O)NC1CCNC1.N#Cc1cc2ccccc2c(Cl)n1>>CC(C)(C)OC(=O)NC1CCN(c2nc(C#N)cc3ccccc23)C1,,CN1CCCC1=O,,CCN(CC)CC,,test
US20120010190A1,CCOC(=O)c1cccc(C(CC(=O)c2ccc(OC)nc2)c2ccc(Cl)cc2F)c1>>CCOC(=O)c1cccc(C(CC(=O)c2ccc(=O)[nH]c2)c2ccc(Cl)cc2F)c1,,C1COCCO1,,Cl,,test
US20150252059A1,C=CC[Mg]Cl.CC(C)(C)OC(=O)N[C@@](C)(C=O)c1cc(Br)ccc1F>>C=CCC(O)[C@](C)(NC(=O)OC(C)(C)C)c1cc(Br)ccc1F,,C1CCOC1,,,,test
US20130023545A1,Cc1cc(-c2nc3cnc(Cl)nc3o2)cc(C)c1O.O=C(OCc1ccccc1)C1CC(O)C1>>Cc1cc(-c2nc3cnc(Cl)nc3o2)cc(C)c1OC1CC(C(=O)OCc2ccccc2)C1,,C1CCOC1,CCN(CC)CC,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05709911,CCOC(=O)CCC=C[C@@H]1CC[C@@H](c2cccc(F)c2F)CC1>>CCOC(=O)CCCC[C@@H]1CC[C@@H](c2cccc(F)c2F)CC1,,CCOC(C)=O,,,,test
US20050054701A1,COC(=O)c1cn2ccnc2c(F)c1Nc1ccc(C)cc1F.O=C1CCC(=O)N1I>>COC(=O)c1cn2c(I)cnc2c(F)c1Nc1ccc(C)cc1F,,CC#N,CCOC(C)=O,,,test
US20040063999A1,COC(=O)[C@H]1CCC[C@@H]1O.NN>>NNC(=O)[C@H]1CCC[C@@H]1O,,CC(C)O,,O,,test
US20020151572A1,Nc1cccc(-c2ccc(C3CCNC3=O)cc2F)n1>>Nc1cccc(-c2ccc(C3CCNC3)cc2F)n1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070060607A1,CCOC(=O)c1cnc(Cl)c2c(COc3cccc(SCc4ccccc4)c3)csc12.N>>CCOC(=O)c1cnc(N)c2c(COc3cccc(SCc4ccccc4)c3)csc12,,C1COCCO1,,,,test
US05073556,FCC1CN(Cc2ccccc2)CC(CF)N1Cc1ccccc1>>FCC1CNCC(CF)N1,[Pd],CO,,Cl,[H][H],test
US20090306078A1,COC(=O)c1ccc(O)c(NC(=O)COc2ccc(C34CC5CC(CC(C5)C3)C4)cc2)c1>>CC(C)(C)c1ccc(OCC(=O)Nc2cc(C(=O)O)ccc2O)cc1,,C1COCCO1,O,Cl,[K+].[OH-],test
US20070281918A1,CC1CN(C(=O)C(F)(F)F)CCc2nc(OC(F)F)ccc21>>CC1CNCCc2nc(OC(F)F)ccc21,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20030032642A1,CC(C)(N)CO.Nc1nc2nc(SCc3ccccc3)nc(Cl)c2s1>>CC(C)(CO)Nc1nc(SCc2ccccc2)nc2nc(N)sc12,,C1CCOC1,,,,test
US20030065005A1,O=[N+]([O-])c1c(Cl)nc2c(c1NCCOCCCc1cccnc1)CCCC2.Oc1ccccc1>>O=[N+]([O-])c1c(Oc2ccccc2)nc2c(c1NCCOCCCc1cccnc1)CCCC2,,COCCOCCOC,,[H-].[Na+],,test
US20040092507A1,CC(C)(C)OC(=O)N1CCN(c2ccccc2CNS(C)(=O)=O)CC1.CI>>CN(Cc1ccccc1N1CCN(C(=O)OC(C)(C)C)CC1)S(C)(=O)=O,,C1CCOC1,CCOCC,[H-].[Na+],,test
US06407112B1,O=C1Nc2cccc3c2[C@@]1(CCCCBr)CCC3.c1ccc2c(c1)CCNC2>>O=C1Nc2cccc3c2[C@@]1(CCCCN1CCc2ccccc2C1)CCC3,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US04751295,CC(C)(C)OC(=O)Nc1nc(C(=NOC2CCCC2)C(=O)O)ns1>>Nc1nc(C(=NOC2CCCC2)C(=O)O)ns1,,O=C(O)C(F)(F)F,,,,test
US09187462B2,CC(C)(C)OC(=O)N1CCC[C@H]1[C@@H](C(=O)O)c1ccc(C(F)(F)F)c(F)c1.OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@H]1[C@@H](NC(=O)OCc1ccccc1)c1ccc(C(F)(F)F)c(F)c1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20040209921A1,CC(C)(C)OC(=O)NC1CCC(NCc2ncccc2-c2ccccc2)CC1.Cc1cccnc1C=O>>Cc1cccnc1CN(Cc1ncccc1-c1ccccc1)C1CCC(NC(=O)OC(C)(C)C)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US08563746B2,COC(=O)CO.C[Si](C)(C)CCOCn1c(S(C)(=O)=O)nc2cc(-c3ccc(-c4ccn[nH]4)cc3)c(Cl)cc21>>C[Si](C)(C)CCOCn1c(OCC(=O)O)nc2cc(-c3ccc(-c4ccn[nH]4)cc3)ccc21,,C1CCOC1,CC#N,[H-].[Na+],,test
US04806549,CCCC(=O)c1cnc2c(C)cccc2c1Cl.Cc1ccccc1N>>CCCC(=O)c1cnc2c(C)cccc2c1Nc1ccccc1C,,C1CCOC1,,,,test
US05659065,CO.COc1ccc(C=O)cc1OCCCBr>>COCCCOc1cc(CO)ccc1OC,,CO,,O,C[O-].[Na+],test
US05470851,C1CNCCN1.ClCCN1CCN2c3ccccc3Cc3ccccc3[C@@H]2C1>>c1ccc2c(c1)Cc1ccccc1N1CCN(CCN3CCNCC3)C[C@@H]21,,CC(=O)O,,Cc1ccccc1,O,test
US20160096834A1,CS(=O)(=O)OCc1ccc(Br)cn1.O=C1NCCOc2cc(C3CC3)cc(F)c21>>O=C1c2c(F)cc(C3CC3)cc2OCCN1Cc1ccc(Br)cn1,,C1CCOC1,,[H-].[Na+],,test
US05646173,CC(C)Br.CC(Cn1ccc2c1-c1cc(O)ccc1C2)N=[N+]=[N-]>>CC(Cn1ccc2c1-c1cc(OC(C)C)ccc1C2)N=[N+]=[N-],,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05864039,CC(C)(C)OC(=O)N1CC[C@H](CN=[N+]=[N-])[C@H](O)C1.CI>>CO[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1CN=[N+]=[N-],,CN(C)C=O,,O,[H-].[Na+],test
US20100240725A1,COc1ccc(C(O)c2ccc(C#N)cc2CO)cc1>>COc1ccc(C2OCc3cc(C#N)ccc32)cc1,,CCOC(C)=O,,O=P(O)(O)O,,test
US20120065195A1,CC1(C)Cc2ccc(Br)cc2C2(COC(N)=N2)C1.N#Cc1cncc(B(O)O)c1>>CC1(C)Cc2ccc(-c3cncc(C#N)c3)cc2C2(COC(N)=N2)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20080004309A1,CCOC(=O)c1nc(Br)c2sc(-c3ccccc3)nc2c1O.C[Sn](C)(C)C>>CCOC(=O)c1nc(C)c2sc(-c3ccccc3)nc2c1O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,,,test
US20130109661A1,CCOC(CCl)OCC.COC(=O)c1ccc(-c2cc(Br)c(N)nn2)cc1>>COC(=O)c1ccc(-c2cc(Br)c3nccn3n2)cc1,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20150119362A1,COC(=O)Cc1ccc(S)cc1.Clc1cccc(-c2cc(Cl)c3c(n2)CCC3)c1>>COC(=O)Cc1ccc(Sc2cc(-c3cccc(Cl)c3)nc3c2CCC3)cc1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US05958954,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2ccc(CC)cc2)=CC(C)(C)O3)cc1F>>CCc1ccc(C2=CC(C)(C)Oc3ccc(C#Cc4ccc(C(=O)O)c(F)c4)cc32)cc1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20080058342A1,C1CCNC1.COc1cc2c(Oc3ccc4[nH]c(C)cc4c3)ncnc2cc1OCCN1CCN(C(=O)CCl)CC1>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3)ncnc2cc1OCCN1CCN(C(=O)CN2CCCC2)CC1,,CN(C)C=O,,[I-].[K+],,test
US04747875,CCCCCCOc1cccc(N(CC)CC)c1.CCn1c(C)c(C(=O)c2ncccc2C(=O)O)c2ccccc21>>CCCCCCOc1cc(N(CC)CC)ccc1C1(c2c(C)n(CC)c3ccccc23)OC(=O)c2cccnc21,,CC(=O)OC(C)=O,,,,test
US03994884,CC(C)(C)OC(=O)C1=C(CBr)CS[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N12.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CC(C)(C)OC(=O)C1=C(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)CS[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N12.[Br-],,CCOC(C)=O,,,,test
US05821256,CC(C)(C)c1ccc(S(=O)(=O)NC(=O)C(Oc2ccc3c(c2)C(=O)NC3=O)c2ccc(N)cc2)cc1.CC=O>>CCNc1ccc(C(Oc2ccc3c(c2)C(=O)NC3=O)C(=O)NS(=O)(=O)c2ccc(C(C)(C)C)cc2)cc1,Cl[Ti](Cl)(Cl)Cl,CO,,Cl,[BH3-]C#N.[Na+],test
US20030087925A1,CC[C@H]1CC[C@H]([N+](=O)[O-])[C@H](c2ccccc2)N1>>CCC1CCC(N)C(c2ccccc2)N1,[Ni],CO,,Br,,test
US04227000,COc1ccc(Cc2cnc(N[N+](=O)[O-])[nH]c2=O)cn1.Cc1[nH]cnc1CSCCN>>COc1ccc(Cc2cnc(NCCSCc3nc[nH]c3C)[nH]c2=O)cn1,,CCO,,,,test
US20040132727A1,COc1cc(CO)cc(OC)c1.COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc(OC)c(COC(=O)Nc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2)c1,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20080114044A1,COC(=O)COc1ccc(-c2noc(-c3ccccc3)c2C(=O)NCCOc2ccc(Cl)cc2Cl)cc1C>>Cc1cc(-c2noc(-c3ccccc3)c2C(=O)NCCOc2ccc(Cl)cc2Cl)ccc1OCC(=O)O,,COCCOC,O,[Li+].[OH-],,test
US05254546,CCCc1nc(I)c(C=O)[nH]1.OB(O)c1cccc2ccccc12>>CCCc1nc(-c2cccc3ccccc23)c(C=O)[nH]1,,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20120029190A1,CC1CN(C(=O)OCc2ccccc2)CC(N)C1O.CC1CN(C(=O)OCc2ccccc2)CC(O)C1N.CCN=C=NCCCN(C)C.O=C(O)c1ccccn1.On1nnc2ccccc21>>CC1CN(C(=O)OCc2ccccc2)CC(NC(=O)c2ccccn2)C1O.CC1CN(C(=O)OCc2ccccc2)CC(O)C1NC(=O)c1ccccn1,,ClCCl,,,,test
US04581155,CO.Cc1ccccc1.N=C(N)c1ccc(F)cc1>>CCCc1cnc(-c2ccc(F)cc2)nc1,,CO,,Cl,,test
US20080161303A1,Cc1ccc(C(=O)NNC(=O)OC(C)(C)C)cc1-c1ccn2c(-c3ccccc3Cl)nnc2c1>>Cc1ccc(C(=O)NN)cc1-c1ccn2c(-c3ccccc3Cl)nnc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04886834,COc1ccc(C(=CC(=O)O)c2ccc(OC)cc2)cc1.NCc1ccccc1>>COc1ccc(C(=CC(=O)NCc2ccccc2)c2ccc(OC)cc2)cc1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,CCOC(=O)Cl,test
US20140329822A1,COc1cc(O)cc(C(=O)NCC2CCN(c3ccnc(-c4cccc(-n5cccn5)c4)n3)CC2)c1.Fc1ccc(CCl)cc1>>COc1cc(OCc2ccc(F)cc2)cc(C(=O)NCC2CCN(c3ccnc(-c4cccc(-n5cccn5)c4)n3)CC2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06245478B1,C1CCC(NC2CCCCC2)CC1.O=C(Cl)NC1CCCCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.O=C1CCC(=O)N1O.c1ccncc1>>O=C(Cl)N(C1CCCCC1)C1CCCCC1.O=C1CCC(=O)N1OC(=O)N(C1CCCCC1)C1CCCCC1,,O,c1ccncc1,,,test
US05380742,C=C(C)c1scc2c1CN(C(=O)OC(C)(C)C)C2>>CC(C)c1scc2c1CN(C(=O)OC(C)(C)C)C2,[Pd],CO,,O=C[O-].[NH4+],,test
US20120184527A1,Clc1ccnc(Cl)c1I.NN>>NNc1nccc(Cl)c1I,,C1COCCO1,ClCCl,O,,test
US20090018122A1,NCCOc1ccccc1.O=[N+]([O-])c1cnc2cc(OCc3ccccc3)ccc2c1Cl>>O=[N+]([O-])c1cnc2cc(OCc3ccccc3)ccc2c1NCCOc1ccccc1,,ClCCl,,CCN(CC)CC,O,test
US20150038437A1,CCOC(=O)c1cc2cc(Br)sc2[nH]1.CI>>CCOC(=O)c1cc2cc(Br)sc2n1C,,CN(C)C=O,,[H-].[Na+],,test
US20060094707A1,COC(=O)C[C@H](Cc1cc(C)c2[nH]ncc2c1CO)C(=O)OC.O=S(Cl)Cl>>COC(=O)C[C@H](Cc1cc(C)c2[nH]ncc2c1CCl)C(=O)OC,,ClCCl,,,,test
US20020045122A1,CCC(=O)C[S+]1CCCCC1.O=S(=O)([O-])C(F)(F)F>>CCC(=O)C[S+]1CCCC1.O=S(=O)([O-])C(F)(F)F,,CC#N,,[Br-].[K+],,test
US20050137171A1,O=P(Cl)(c1ccccc1)c1ccccc1.Oc1ccc2[nH]nc(C=Cc3ccccc3)c2c1>>O=P(Oc1ccc2[nH]nc(/C=C/c3ccccc3)c2c1)(c1ccccc1)c1ccccc1,,ClCCl,,O,c1c[nH]cn1,test
US20130178459A1,COc1ccc(-c2ccc(C(=O)N(COCC[Si](C)(C)C)c3ccc(N4CC[C@H](NC(=O)OC(C)(C)C)C4)cc3Br)s2)cc1>>COc1ccc(-c2cc3c(s2)c(=O)n(COCC[Si](C)(C)C)c2ccc(N4CC[C@H](N)C4)cc32)cc1,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,,,,,test
US20090069250A1,CCOC(=O)C(N=C(c1ccccc1)c1ccccc1)c1ccc(C(=O)OC(C)(C)C)cc1>>CCOC(=O)C(N)c1ccc(C(=O)O)cc1,,CCOCC,,Cl,,test
US20100120761A1,CC#C[Mg]Br.CON(C)C(=O)c1ccn2ccnc2c1>>CC#CC(=O)c1ccn2ccnc2c1,,C1CCOC1,,,,test
US06127414,COc1ccc([C@@H](C)NC(=O)[C@@H](CCCNC(=S)NC(=O)c2ccccc2)NC(=O)C(c2ccccc2)c2ccccc2)cc1>>COc1ccc([C@@H](C)NC(=O)[C@@H](CCCNC(N)=S)NC(=O)C(c2ccccc2)c2ccccc2)cc1,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20030171411A1,CCOC(=O)Cc1csc(N)n1.O=C(Cl)C(Br)CC1CCCCC1>>CCOC(=O)Cc1csc(NC(=O)C(Br)CC2CCCCC2)n1,,C1CCOC1,,,,test
US20120157436A1,O=C(Cl)C(=O)Cl.O=C(O)c1ccc(F)c(Cl)c1Cl>>O=C(Cl)c1ccc(F)c(Cl)c1Cl,CN(C)C=O,ClCCl,,,,test
US20030096826A1,CCOC(OCC)C(CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccc(NC(C)=O)cc1OCCc1ccc(C(=O)OC)c2ccccc12>>CCOC(OCC)C(CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccc(NC(C)=O)cc1OCCc1ccc(C(=O)O)c2ccccc12,,C1CCOC1,CCOC(C)=O,Cl,[Li+].[OH-],test
US20140080804A1,CCOC(=O)CC(=O)CC(=O)OCC.NC=S>>CCOC(=O)Cc1ncsc1C(=O)OCC,,CCO,,O=S(Cl)Cl,,test
US20050233988A1,Brc1cccc(Br)c1.CCc1ccc(C=O)s1>>CCc1ccc(C(O)c2cccc(Br)c2)s1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20160237090A1,CC(COS(C)(=O)=O)N(Cc1ccn[nH]1)C(=O)OC(C)(C)C>>CC1Cn2nccc2CN1C(=O)OC(C)(C)C,,CN(C)C=O,,O,[H-].[Na+],test
US20160251339A1,COc1ccc(S(=O)(=O)Cl)cc1N1CCN(C(=O)C(Cl)(Cl)Cl)CC1.Cc1c[nH]c2cc(Br)ccc12>>COc1ccc(S(=O)(=O)n2cc(C)c3ccc(Br)cc32)cc1N1CCN(C(=O)C(Cl)(Cl)Cl)CC1,,C1CCOC1,,[H-].[Na+],,test
US04640849,C=CCBr.O=Cc1ccc(O)cc1>>C=CCc1cc(C=O)ccc1O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130210844A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1cc(C#N)cnc1C(F)F>>CCOC(=O)c1cc(CNC(=O)OC(C)(C)C)cnc1C(F)F,[Pd],CCO,,CCN(CC)CC,,test
US05482969,O=[N+]([O-])c1cc(S(=O)(=O)c2ccccc2)ccc1Cl>>Nc1cc(S(=O)(=O)c2ccccc2)ccc1Cl,,CCO,,ClCCl,,test
US20090110938A1,CCN(CC)CC.N#CCl.O=C1OC(c2ccc(O)cc2)(c2ccc(O)cc2)c2ccccc21>>N#COc1ccc(C2(c3ccc(OC#N)cc3)OC(=O)c3ccccc32)cc1,,ClCCl,,,,test
US20110060026A1,CCOC(=O)Cc1c(C)n(Cc2ccccc2S(=O)(=O)c2ccc(F)cc2)c2ccc(F)cc12>>Cc1c(CC(=O)O)c2cc(F)ccc2n1Cc1ccccc1S(=O)(=O)c1ccc(F)cc1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20100292279A1,CC(C)(C)NS(=O)(=O)c1ccccc1S(=O)(=O)NC(C)(C)C>>NS(=O)(=O)c1ccccc1S(N)(=O)=O,,ClCCl,,BrB(Br)Br,,test
US20050085458A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CCOP(=O)(Cc1cccc([N+](=O)[O-])c1)OCC>>CC(C)(C)OC(=O)N1CCC(=Cc2cccc([N+](=O)[O-])c2)CC1,,C1CCOC1,,[H-].[Na+],,test
US03965095,CC(C)(C)N(Cc1ccccc1)CC(COc1cccc2c1CC(=O)N2)OC(=O)c1cccnc1>>CC(C)(C)NCC(COc1cccc2c1CC(=O)N2)OC(=O)c1cccnc1,[Pd],C1CCOC1,,[H][H],,test
US04638060,CC(C)(C)OC(=O)NC(C(=O)OCc1ccccc1)C1(O)CCC1>>CC(C)(C)OC(=O)NC(C(=O)O)C1(O)CCC1,[Pd],CCO,,,,test
US20150038528A1,COC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O.NC1(CC(=O)O)CCC1>>N#Cc1nc(C(=O)NC2(CC(=O)O)CCC2)c(O)c2ccc(Oc3ccccc3)cc12,,CC(=O)N(C)C,O,Cl,C[O-].[Na+],test
US20080227724A1,CCCCCCCCCCCCCCCCCC(=O)Cl.N[C@H]1CCCNC(=O)C1>>CCCCCCCCCCCCCCCCCC(=O)N[C@H]1CCCNC(=O)C1,,ClCCl,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20140329798A1,C1CNC1.O=C(O)Cc1ccc(OCC[C@@H]2C[C@@H]2C2CCN(c3ncc(Cl)cn3)CC2)cc1F>>O=C(Cc1ccc(OCC[C@@H]2C[C@@H]2C2CCN(c3ncc(Cl)cn3)CC2)cc1F)N1CCC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150057265A1,Cn1ncc([N+](=O)[O-])c1N1CCCC(NC(=O)OC(C)(C)C)CC1>>Cn1ncc(N)c1N1CCCC(NC(=O)OC(C)(C)C)CC1,[Fe],O,,CCO,[Cl-].[NH4+],test
US20110244481A1,CC(C)(C)[Si](C)(C)Oc1ccc(-c2cnc(N)c(Br)n2)cc1.OB(O)c1ccsc1>>CC(C)(C)[Si](C)(C)Oc1ccc(-c2cnc(N)c(-c3ccsc3)n2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],test
US05780642,CC1(C)COC(c2ccc(C(C)(C)NCC(O)Cn3ccnc3)cc2)=N1.CCCO>>CCCOC(=O)c1ccc(C(C)(C)NCC(O)Cn2ccnc2)cc1,,CCCO,,O,O=S(=O)(O)O,test
US20150315188A1,CC1(c2ccncc2)CO1.Cc1cc(F)c2[nH]c3c(c2c1)CN1CCCC1C3>>Cc1cc(F)c2c(c1)c1c(n2CC(C)(O)c2ccncc2)CC2CCCN2C1,,CN(C)C=O,,[H-].[Na+],,test
US20070197512A1,C=CC(=O)OC.CC(C)C1Oc2ccc(C(F)(F)F)cc2NC1=O>>COC(=O)CCN1C(=O)C(C(C)C)Oc2ccc(C(F)(F)F)cc21,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US09296698B2,Brc1cscn1.COc1ccc(CNc2nc3ccc(B4OC(C)(C)C(C)(C)O4)cc3cc2CCC(=O)NCC2CCCCC2)cc1>>Nc1nc2ccc(-c3cscn3)cc2cc1CCC(=O)NCC1CCCCC1,,CCO,O,CC(=O)[O-].[K+],,test
US20030216373A1,CS(=O)(=O)Cl.O=C1O[C@@H](CO)CN1c1ccc(C2=CCSCC2)c(F)c1>>CS(=O)(=O)OC[C@H]1CN(c2ccc(C3=CCSCC3)c(F)c2)C(=O)O1,,ClCCl,,CCN(CC)CC,,test
US20120329775A1,CC(C)(C)OC(=O)NC1(C(=O)N[C@@H](Cc2ccc(-c3cccc(C#N)c3)cc2)C(N)=O)CCOCC1>>CC(C)(C)OC(=O)NC1(C(=O)N[C@H](C#N)Cc2ccc(-c3cccc(C#N)c3)cc2)CCOCC1,,ClCCl,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US20130023526A1,COc1cc(CNC(=O)c2cc(CO)nc(C)n2)ccc1F>>COc1cc(CNC(=O)c2cc(C=O)nc(C)n2)ccc1F,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20090253677A1,CN(Cc1ccccc1)C12CCC(CC1)Cn1c2nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O>>CNC12CCC(CC1)Cn1c2nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O,[Pd],CO,,,,test
US03935311,Cc1ncc(CO)cc1O.ClCc1ccccc1>>Cc1ncc(CO)cc1OCc1ccccc1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20100093703A1,C1CNCCN1.O=[N+]([O-])c1ccc2c(c1)CCN2c1ccc(Cl)nn1>>O=[N+]([O-])c1ccc2c(c1)CCN2c1ccc(N2CCNCC2)nn1,,ClCCl,O,CO,,test
US20120035214A1,COCC(F)(F)COCc1ccc([C@@]2(O)CCN(C(=O)OC(C)(C)C)C[C@@H]2c2ccc(-c3ccccc3CCNC(C)=O)cc2C)cn1>>COCC(F)(F)COCc1ccc([C@@]2(O)CCNC[C@@H]2c2ccc(-c3ccccc3CCNC(C)=O)cc2C)cn1,,ClCCl,,C1COCCO1,Cl,test
US20150166480A1,CC(C)(F)CN1CCC(COc2ccc(Br)cn2)CC1.CCOC(=O)c1ccc(B(O)O)cc1F>>CCOC(=O)c1ccc(-c2ccc(OCC3CCN(CC(C)(C)F)CC3)nc2)cc1F,,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04705793,CC#CCCn1ncc(C#N)c1NC1=CC(=O)N(CCCC)C1>>CC#CCCn1ncc2c(N)c3c(nc21)CN(CCCC)C3=O,,CCCCCCC,ClCCl,C[Al](C)C,,test
US20130237519A1,COC(=O)c1ccc(-c2ccn3c(C(=O)Nc4cc(C(=O)NCc5ccc(F)c(F)c5)ccc4F)cnc3c2)cc1F>>O=C(NCc1ccc(F)c(F)c1)c1ccc(F)c(NC(=O)c2cnc3cc(-c4ccc(C(=O)O)c(F)c4)ccn23)c1,,CO,,[Na+].[OH-],,test
US20080176857A1,CC(=O)C(C)S.CCc1cc2c(N3CCN(C(=O)Cc4ccccc4)CC3)nc(Cl)nc2s1>>CCc1cc2c(N3CCN(C(=O)Cc4ccccc4)CC3)nc(SC(C)C(C)=O)nc2s1,,CN(C)C=O,,,,test
US05389293,CC(=O)O.CC(O)CCc1ccccc1>>CC(=O)OC(C)CCc1ccccc1,CN(C)c1ccncc1,c1ccncc1,,Cc1ccccc1,Cl,test
US20130331378A1,COC(=O)c1cc(CCCSC)cc(Cc2c(-c3ccccc3)nn3c([Si](C)(C)C)c(OC)ccc23)n1>>COC(=O)c1cc(CCCSC)cc(Cc2c(-c3ccccc3)nn3cc(OC)ccc23)n1,,O,,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100216810A1,N#CC1(c2cccc(C(=O)O)c2Cl)CC1.N#Cc1c(Oc2cccc(N)c2)ccc2nc(NC(=O)C3CC3)sc12>>N#Cc1c(Oc2cccc(NC(=O)c3cccc(C4(C#N)CC4)c3Cl)c2)ccc2nc(NC(=O)C3CC3)sc12,,C1CCOC1,CCOC(C)=O,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20120058988A1,C1COCCN1.CC(C)(O)c1ccc2c(c1)[nH]c1c(C(N)=O)cc(-c3ccc(CN4CCOCC4)c(Cl)c3)cc12>>CC(C)(c1ccc2c(c1)[nH]c1c(C(N)=O)cc(-c3ccc(CN4CCOCC4)c(Cl)c3)cc12)N1CCOCC1,,ClCCl,,Cl,,test
US20140018313A1,CC(C)(C)OC(=O)N1[C@@H]2CC[C@@H](C2)[C@H]1c1nc2ccc3cc(Br)ccc3c2[nH]1.COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc2ccc3cc(B4OC(C)(C)C(C)(C)O4)ccc3c2[nH]1)C(C)C>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc2ccc3cc(-c4ccc5c(ccc6nc([C@@H]7[C@H]8CC[C@H](C8)N7C(=O)OC(C)(C)C)[nH]c65)c4)ccc3c2[nH]1)C(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20130237525A1,CCOC(=O)c1ccc(O)cc1.FCCI>>CCOC(=O)c1ccc(OCCF)cc1,,CN(C)C=O,O,CCOCC,O=C([O-])[O-].[K+].[K+],test
US06380288B1,NNS(=O)(=O)c1ccccc1.O=Cc1ccccc1>>O=S(=O)(NN=Cc1ccccc1)c1ccccc1,,CO,,,,test
US20120083501A1,CN=C=S.COC(=O)C1(N)c2cc(Br)ccc2OC2CCCCC21>>CN1C(=O)C2(NC1=S)c1cc(Br)ccc1OC1CCCCC12,,CN(C)C=O,,CCN(CC)CC,,test
US20050267093A1,C#CC(=O)O.Ic1ccc2c(c1)CCC2N1CCCC1>>O=C(O)C#Cc1ccc2c(c1)CCC2N1CCCC1,[Cu]I,CC#N,,CCN(CC)CC,,test
US20110257100A1,O=[N+]([O-])c1ccc(Oc2ccnc3cc(-c4cn(CCN5CCCC5)nn4)sc23)c(F)c1>>Nc1ccc(Oc2ccnc3cc(-c4cn(CCN5CCCC5)nn4)sc23)c(F)c1,[Zn],CO,O,[Cl-].[NH4+],,test
US04366320,CCOC(=O)NNC(=O)Nc1c(F)c(F)c(F)c(F)c1F>>O=c1[nH][nH]c(=O)n1-c1c(F)c(F)c(F)c(F)c1F,,O,,O=C([O-])[O-].[K+].[K+],,test
US20060247297A1,CC(C)Cc1ccc([C@@H](C)C(=O)O)cc1.ClCCl.O=S(Cl)Cl.c1ccncc1>>CC(C)Cc1ccc([C@@H](C)C(=O)CC(=O)O)cc1,,ClCCl,,C1COCCO1,Cl,test
US20130109711A1,CN1CCC2(CCCNC2)C1=O.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1Cl>>CN1CCC2(CCCN(S(=O)(=O)c3ccc(C(F)(F)F)cc3Cl)C2)C1=O,,ClCCl,,CCN(CC)CC,Cl,test
US20060040918A1,CNC(=O)c1ccc(Oc2ccc3c(c2)CCN(C(=O)OC(C)(C)C)CC3)nc1>>CNC(=O)c1ccc(Oc2ccc3c(c2)CCNCC3)nc1,,C1COCCO1,,Cl,,test
US20120016139A1,CC(=O)C=Cc1ccccc1>>CC(=O)CCc1ccccc1,,CO,,[H][H],,test
US20150203502A1,C[Si](C)(C)CCOCCl.Fc1c[nH]c2nc(Cl)nc(Cl)c12>>C[Si](C)(C)CCOCn1cc(F)c2c(Cl)nc(Cl)nc21,,CN(C)C=O,,[H-].[Na+],,test
US20140336224A1,CCI.N#CC(C(=O)c1cccc([N+](=O)[O-])c1Cl)c1ccc(Cl)cc1>>CCO/C(=C(/C#N)c1ccc(Cl)cc1)c1cccc([N+](=O)[O-])c1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020115853A1,COc1cc(-c2cccc([N+](=O)[O-])c2)ccc1N>>Nc1ccc(-c2cccc([N+](=O)[O-])c2)cc1O,,ClCCl,,BrB(Br)Br,,test
US20040259888A1,CN1CCNCC1.Fc1ccc(-c2c(-c3ccccc3)oc3ncnc(Cl)c23)cc1>>CN1CCN(c2ncnc3oc(-c4ccccc4)c(-c4ccc(F)cc4)c23)CC1,,O,,,,test
US20080293711A1,NCc1ccc(C(=O)N(Cc2ccccc2)N2CCOCC2)cc1.O=C(Cl)c1cccs1>>O=C(NCc1ccc(C(=O)N(Cc2ccccc2)N2CCOCC2)cc1)c1cccs1,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20150133512A1,C[C@@H](O)c1cccc(C(F)(F)F)c1.Cc1nnn(-c2ccc(Br)cc2)c1C(=O)O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cc1nnn(-c2ccc(Br)cc2)c1NC(=O)O[C@H](C)c1cccc(C(F)(F)F)c1,,Cc1ccccc1,,CCN(CC)CC,,test
US20150094319A1,Nc1ccccn1.O=C(O)c1ccc(Br)cc1>>O=C(Nc1ccccn1)c1ccc(Br)cc1,,c1ccncc1,,O=P(Cl)(Cl)Cl,,test
US20110309307A1,COc1ccc2sc(=O)oc2c1>>COc1ccc(S)c(O)c1,,CO,O,Cl,[K+].[OH-],test
US20040034011A1,CCCCCCC(=O)Cl.COc1cc2ccccc2cc1OC>>CCCCCCC(=O)c1ccc2cc(OC)c(OC)cc2c1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20080176884A1,COC1CC[C@@]2(O)[C@H]3Cc4ccc(OCc5ccccc5)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5.COS(=O)(=O)C(F)(F)F>>COC1CC[C@@]2(O)[C@H]3Cc4ccc(OCc5ccccc5)c5c4[C@@]2(CC[N+]3(C)CC2CC2)[C@H]1O5.O=S(=O)([O-])C(F)(F)F,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20020040144A1,CN1CCC(C2CCN(C(N)=O)CC2)CC1.O=C(N[C@@H](C(=O)O)c1ccccc1)OCc1ccccc1>>CN1CCC(C2CCN(C(N)=O)CC2)CC1.N[C@@H](C(=O)O)c1ccccc1,[Pd],CO,,[H][H],,test
US20050059713A1,O=C(O)c1cc(Br)ccc1O.OB(O)c1ccc(F)c(Cl)c1>>O=C(O)c1cc(-c2ccc(F)c(Cl)c2)ccc1O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20050197328A1,CCn1c(-c2nonc2N)nc2cncc(C=O)c21.Fc1ccc(N2CCNCC2)cc1>>CCn1c(-c2nonc2N)nc2cncc(CN3CCN(c4ccc(F)cc4)CC3)c21,,ClCCCl,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05436264,CC(C)(Cc1c[nH]c2ccc(Cl)cc12)[N+](=O)[O-]>>CC(C)(N)Cc1c[nH]c2ccc(Cl)cc12,[Ni],CCO,,NN,O,test
US20130096113A1,COc1cc2c(cc1Br)ncn2Cc1ccc2nc(N[C@@H]3CCCC[C@H]3O)sc2c1>>COc1ccc2ncn(Cc3ccc4nc(N[C@@H]5CCCC[C@H]5O)sc4c3)c2c1,[Zn],C1COCCO1,,[Na+].[OH-],,test
US20030114649A1,CC1(c2ccccc2)SC(=S)N(Nc2ccccc2)C1=N.O>>CC1(c2ccccc2)SC(=S)N(Nc2ccccc2)C1=O,,CO,,Cl,,test
US20110166128A1,CCCCCCCCCC(=O)OC[C@H](COC(=O)OCI)OC(=O)CCCCCCCCC.Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1>>CCCCCCCCCC(=O)OC[C@@H](COC(=O)OC[N+]1(C)CCN(C2=Nc3ccccc3Nc3sc(C)cc32)CC1)OC(=O)CCCCCCCCC.[I-],,CCOC(C)=O,CCOCC,,,test
US20160058763A1,NO.O=Cc1ccc(Br)c2cncnc12>>ON=Cc1ccc(Br)c2cncnc12,,CC#N,,CCN(CC)CC,Cl,test
US04902835,Br[Mg]c1ccccc1.CCOCC.COC(F)(F)C(F)=CCBr>>COC(=O)/C(F)=C/Cc1ccccc1,,CCOCC,,C1CCOC1,,test
US04374139,C=CC#N.CC(=O)c1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)NCC3>>CC(=O)c1ccc2c(c1)[C@@]13CCCC[C@H]1[C@@H](C2)N(CCC#N)CC3,,CCO,,CCN(CC)CC,,test
US05164390,Clc1ncnc2nc[nH]c12.NCC(O)CN1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1>>OC(CNc1ncnc2nc[nH]c12)CN1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1,,CO,,CCN(CC)CC,,test
US06492416B1,C#CC(C)(O)CC.C1CCOC1.Cc1ccc(C=S)cc1>>CCC(C)(O)C#CC(O)c1ccc(SC)cc1,,CCCCCC,,[Li]CCCC,,test
US20020019569A1,NO.O=CCCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl>>ON=CCCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl,,c1ccncc1,,Cl,Cl,test
US20140336185A1,COC(=O)CNCc1ccc(-c2noc(-c3ccc(-c4ccc(C)cc4)cc3)n2)cc1.COc1ccc(CC(=O)Nc2ccc(C(=O)O)c(F)c2)c(C(F)(F)F)c1>>COC(=O)CN(Cc1ccc(-c2noc(-c3ccc(-c4ccc(C)cc4)cc3)n2)cc1)C(=O)c1ccc(NC(=O)Cc2ccc(OC)cc2C(F)(F)F)cc1F,,CCOC(C)=O,CN(C)C=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20060223801A1,Cc1[nH]c(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)c(Cl)c1Cl.Cl>>Cc1[nH]c(C(=O)NC2CCNCC2)c(Cl)c1Cl.Cl,,C1COCCO1,,,,test
US04507498,CCCc1c(O)ccc(C(C)=O)c1O.CCCc1c(OCC(=O)OCC)ccc(C(C)=O)c1OCCOCCOCCOS(C)(=O)=O>>CCCc1c(OCCOCCOCCOc2c(C(C)=O)ccc(OCC(=O)OCC)c2CCC)ccc(C(C)=O)c1O,,CC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04978793,C=COCC.O=[N+]([O-])C(CO)(CO)CO>>CC1OCC(CO)([N+](=O)[O-])CO1,Cl,CC#N,,,,test
US20100010002A1,N#CCCN1CCNCC1.O=C(O)C=Cc1ccc(O)c(O)c1>>N#CCCN1CCN(C(=O)/C=C/c2ccc(O)c(O)c2)CC1,,C1CCOC1,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20100035934A1,CCOC(=O)c1ccn(-c2cccc(Nc3ccc(Cl)cc3)n2)n1>>O=C(O)c1ccn(-c2cccc(Nc3ccc(Cl)cc3)n2)n1,,Cl,,,,test
US05994355,N#CC(c1ccc(Cl)cc1)c1c(Cl)cc(N2N=CCNC2=O)cc1Cl.OO>>N#CC(c1ccc(Cl)cc1)c1c(Cl)cc(-n2ncc(=O)[nH]c2=O)cc1Cl,,CC(=O)O,,,,test
US20120245172A1,CC(C)(C)OC(=O)N1CCOC(c2ccc(NCc3ccc(Cl)cc3)cc2)C1>>Clc1ccc(CNc2ccc(C3CNCCO3)cc2)cc1,,C1CCOC1,C1COCCO1,Cl,[Na+].[OH-],test
US05106871,CC(=O)c1c(O)cc(O)cc1O.CC(C)=CCCl>>CC(=O)c1c(O)cc(O)c(CC=C(C)C)c1O,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20060235004A1,Cc1cn(CCCCN2CCN(c3cc(C(F)(F)F)nc(C(C)(C)C)n3)CC2)c(=O)nc1SC#N.Oc1ccccc1>>Cc1cn(CCCCN2CCN(c3cc(C(F)(F)F)nc(C(C)(C)C)n3)CC2)c(=O)nc1Oc1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05015644,CN(C)c1ccc(C2(C#N)CCCC2)cc1>>CN(C)c1ccc(C2(CN)CCCC2)cc1,[Ni],CO,,N,[H][H],test
US03936492,C=C(C)C(=O)OCC1CO1.CCCCCCCCCCCCCCCCCCNC>>C=C(C)C(=O)OC(CCCCCCCCCCCCCCCCC)N(C)CCCO,,CO,,,,test
US20160046618A1,CC(C)(C)OC(=O)N(COCC[Si](C)(C)C)C1=N[C@](CF)(c2cc(Br)ccc2F)[C@@H]2C[C@]2(c2c[nH]nn2)S1>>NC1=N[C@](CF)(c2cc(Br)ccc2F)[C@@H]2C[C@]2(c2c[nH]nn2)S1,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20080033016A1,CN=C=S.COc1ccc(Cl)cc1C(=O)NCCC1CCN(S(N)(=O)=O)CC1>>CNC(=S)NS(=O)(=O)N1CCC(CCNC(=O)c2cc(Cl)ccc2OC)CC1,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100298336A1,COC(=O)c1ccc([N+](=O)[O-])cc1Cl>>O=[N+]([O-])c1ccc(CO)c(Cl)c1,,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US20100144608A1,CC(C)(C)OC(=O)N[C@H]1CCCCCC=C[C@@H]2C[C@@]2(C(=O)NS(=O)(=O)C2CC2)NC(=O)[C@@H]2C[C@@H](Oc3nc4ccccc4nc3-c3cc4ccccc4s3)CN2C1=O.Cl>>Cl.N[C@H]1CCCCCC=C[C@@H]2C[C@@]2(C(=O)NS(=O)(=O)C2CC2)NC(=O)[C@@H]2C[C@@H](Oc3nc4ccccc4nc3-c3cc4ccccc4s3)CN2C1=O,,C1COCCO1,CCOC(C)=O,,,test
US20040157866A1,CC(=O)OC(C)=O.Cc1ccc(C(=O)Nc2ccc(NCCc3ccccn3)c(N)c2)c(-c2ccc(C(F)(F)F)cc2)c1>>Cc1ccc(C(=O)Nc2ccc3c(c2)nc(C)n3CCc2ccccn2)c(-c2ccc(C(F)(F)F)cc2)c1,,CCOC(C)=O,,,,test
US20160229814A1,CC(C)n1c(=O)n(CC2CC2)c(=O)c2cc(N)ccc21.CC(CC(=O)O)CC(=O)Nc1ccc(C#N)c(Cl)c1>>CC(CC(=O)Nc1ccc(C#N)c(Cl)c1)CC(=O)Nc1ccc2c(c1)c(=O)n(CC1CC1)c(=O)n2C(C)C,CN(C)c1ccncc1,CN(C)C=O,O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20100081643A1,O=C1CCC(=O)N1I.O=[N+]([O-])c1c(F)cc(F)cc1NCc1ccc(-c2ccccc2)cc1>>O=[N+]([O-])c1c(NCc2ccc(-c3ccccc3)cc2)cc(F)c(I)c1F,,CC(=O)O,,,,test
US20140187596A1,CCCCCCCCCNC(=O)c1coc(C2C3CCC(O3)C2Cc2cc(F)ccc2CCC(=O)OC)n1>>CCCCCCCCCNC(=O)c1coc(C2C3CCC(O3)C2Cc2cc(F)ccc2CCC(=O)O)n1,,C1CCOC1,O,[Li+].[OH-],,test
US04772620,Cc1ccc(C(F)(F)F)nc1.O=C1CCC(=O)N1Br>>FC(F)(F)c1ccc(CBr)cn1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20150133422A1,CS(=O)(=O)Cl.O=C(OCc1ccccc1)C1CC(O)C1>>CS(=O)(=O)OC1CC(C(=O)OCc2ccccc2)C1,,ClCCl,,CCN(CC)CC,,test
US20120202794A1,COc1ccc(C(N)c2ccc(OC)cc2)cc1.O=CC(=O)O.OB(O)c1ccco1>>COc1ccc(C(NC(C(=O)O)c2ccco2)c2ccc(OC)cc2)cc1,,ClCCl,,O,,test
US20160083372A1,CCOn1cc(C(=O)O)nn1.C[C@@](CO)(C[C@H](N)Cc1ccc(-c2cc(Cl)ccc2F)cc1)C(=O)O>>CCOn1cc(C(=O)N[C@H](Cc2ccc(-c3cc(Cl)ccc3F)cc2)C[C@@](C)(CO)C(=O)O)nn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130150339A1,COc1cc(Cl)ccc1B(O)O.COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(Cl)nccc3c2)c(OC)c1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>COc1cc(-c2cnn(C)c2)ccc1-c1nccc2cc(S(=O)(=O)Nc3nccs3)ccc12,,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140141034A1,CC(C)(C)OC(=O)NCCCCn1c(=O)[nH][nH]c1=O>>CC(C)(C)OC(=O)NCCCCN1C(=O)N=NC1=O,,ClCCl,,,,test
US20130244998A1,CC(C)(C)OC(=O)N1CC(C2CCN(C(=O)c3nccs3)CC2)C1>>O=C(c1nccs1)N1CCC(C2CNC2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120130129A1,C#CC(=O)O.COc1cccc(C=O)c1OC>>COc1cccc(C(O)C#CC(=O)O)c1OC,,C1CCOC1,,[Li]CCCC,,test
US20110130377A1,COCOCc1nc(-c2ccc(Cl)cc2)oc1C(=O)OC>>COC(=O)c1oc(-c2ccc(Cl)cc2)nc1CO,Cl,CO,O,,,test
US20130102776A1,C=O.C[C@H]1CNC[C@@H](C)N1.O=C1COc2cc(O)ccc21>>C[C@H]1CN(Cc2c(O)ccc3c2OCC3=O)C[C@@H](C)N1,,CCO,,,,test
US05334716,CC(=O)CBr.CCOC(=O)CCCCc1ccccn1>>CCOC(=O)CCCc1c(C)cn2ccccc12,,CC(C)=O,,,,test
US20160222033A1,Cc1sc2nc(C(C)n3nc(C(F)(F)F)cc3C3CC3)cc(=O)n2c1[C@@H]1C[C@H]1CO[Si](C)(C)C(C)(C)C>>Cc1sc2nc(C(C)n3nc(C(F)(F)F)cc3C3CC3)cc(=O)n2c1[C@@H]1C[C@H]1CO,,CCO,,Cl,,test
US06043248,CCN(CC)C(=O)/C=C/C(C)=O>>CCN(CC)C(=O)/C=C/C(C)O,,CO,,[BH4-].[Na+],,test
US20090291977A1,Cc1nc2c(NC3CCOc4ccccc43)cc(C(=O)OC(C)C)cn2c1C.Cl>>Cc1nc2c(NC3CCOc4ccccc43)cc(C(=O)O)cn2c1C.Cl,,O,,CO,[Na+].[OH-],test
US05965553,CC(C)(C=O)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C.Nc1ccc(Cl)cc1C(O)c1cccc2ccccc12>>CC(C)(CNc1ccc(Cl)cc1C(O)c1cccc2ccccc12)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,CC(=O)O,,O,[BH4-].[Na+],test
US08211916B2,C1=C(CCOC(c2ccccc2)c2ccccc2)CCN(Cc2ccccc2)C1.COC(=O)Cl>>COC(=O)N1CC=C(CCOC(c2ccccc2)c2ccccc2)CC1,,c1ccccc1,,,,test
US20140336190A1,C1CCOC1.COC(=O)c1cc(-c2c(C)noc2C)cc2[nH]c(NS(C)(=O)=O)nc12.Cl[Mg]C1CCCC1>>Cc1noc(C)c1-c1cc(C(O)(C2CCCC2)C2CCCC2)c2nc(NS(C)(=O)=O)[nH]c2c1,,C1CCOC1,,,,test
US20090054435A1,COc1ccc(C(=O)c2ccc(Cl)nc2)c(OC(C)(C)C(=O)OC(C)(C)C)c1.Cc1oc(-c2ccccc2)nc1CO>>COc1ccc(C(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)nc2)c(OC(C)(C)C(=O)OC(C)(C)C)c1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20080207897A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(NCCCC=Cc1c(Cl)ccc2c1CCNCC2)C1CCCC1>>CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(C=CCCCNC(=O)C3CCCC3)c2CC1,,ClCCl,,,,test
US20090149425A1,C=CC[Mg]Cl.CC(C)(O)c1cc(C=C(C#N)C#N)no1>>C=CC(c1cc(C(C)(C)O)on1)C(C#N)C#N,[Cu]I,C1CCOC1,C1COCCO1,Cl,,test
US04018768,NNc1nnnc2c1sc1ccccc12>>c1ccc2c(c1)sc1cnnnc12,,O,,,,test
US20060264438A1,CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCC1=O.C[C@@H](N)c1ccccc1>>CCOC(=O)C1=C(N[C@H](C)c2ccccc2)CCN(C(=O)OC(C)(C)C)C1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120101134A1,CCc1c(C=O)cccc1-c1nnc(-c2ccc(OC(C)C)c(Cl)c2)s1.CNCC(=O)O>>CCc1c(CN(C)CC(=O)O)cccc1-c1nnc(-c2ccc(OC(C)C)c(Cl)c2)s1,CC(=O)O,ClCCl,,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090042967A1,CC(=O)Nc1ccc(Br)c(Cl)c1F.N#C[Cu]>>CC(=O)Nc1ccc(C#N)c(Cl)c1F,,CN(C)C=O,,O,,test
US20050009829A1,CCOC(=O)c1c(F)ccc([N+](=O)[O-])c1N.OCC(F)(F)F>>CCOC(=O)c1c(OCC(F)(F)F)ccc([N+](=O)[O-])c1N,,C1CCOC1,,Cl,[H-].[Na+],test
US20140155389A1,CCOC(=O)c1c(Cl)cc(Cl)nc1CBr.C[N+]1([O-])CCCCC1>>CCOC(=O)c1c(Cl)cc(Cl)nc1C=O,,CC#N,,,,test
US05106853,CCC(CC)(C(=O)[O-])C(=O)[O-].CCO.Cc1ccccc1.NC(=NO)C1CC1>>CCOC(=O)Cc1nc(C2CC2)no1,,CCO,O,,,test
US20130085151A1,CC(c1cc2ccsc2nc1Cl)N1C(=O)c2ccccc2C1=O.CCCC[Sn](CCCC)(CCCC)c1ccccn1>>CC(c1cc2ccsc2nc1-c1ccccn1)N1C(=O)c2ccccc2C1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20040254222A1,C[SiH](C)Oc1c(OC(C)(C)C)cccc1Sc1ccc(CCCC2(NC(=O)OC(C)(C)C)COC(C)(C)OC2)c(Cl)c1>>CC(C)(C)OC(=O)NC1(CCCc2ccc(Sc3cccc(O)c3)cc2Cl)COC(C)(C)OC1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US04277394,CC(C)C[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NN>>CC(C)C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NN,[Pd],CO,,CC(=O)O,,test
US20150284396A1,CCCCc1nc(N)c2c(n1)c(C#CCCCCl)cn2COCc1ccccc1.FC1(F)CCNCC1>>CCCCc1nc(N)c2c(n1)c(C#CCCCN1CCC(F)(F)CC1)cn2COCc1ccccc1,,CC#N,,CCN(CC)CC,Cl,test
US20050271584A1,Cc1n[nH]cc1Br.O=[N+]([O-])c1ccc(F)cc1>>Cc1nn(-c2ccc([N+](=O)[O-])cc2)cc1Br,,CS(C)=O,,CC(C)(C)O[K],,test
US20160039797A1,CC(C)(C)OC(=O)Nc1ccc(Oc2ccnc(Cl)n2)c2ccccc12>>Nc1ccc(Oc2ccnc(Cl)n2)c2ccccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US04814343,CI.COCc1ccc(OC)c(Br)c1O>>COCc1ccc(OC)c(Br)c1OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070032525A1,CC(C)(C)OC(=O)n1c(NCC2CCN(Cc3ccc(Cl)c(Cl)c3)CC2)nc2c(N)cccc21.CCN=C=O>>CCNC(=O)Nc1cccc2[nH]c(NCC3CCN(Cc4ccc(Cl)c(Cl)c4)CC3)nc12,,CC#N,,C1COCCO1,Cl,test
US05470993,CC1CC(=O)C2=C1CCCC2.[Li]C>>CC1=CC(C)C2=C1CCCC2,,CCOCC,,,,test
US20120058985A1,CC(=O)Cl.Nc1nc(Cl)cc(Cl)n1>>CC(=O)Nc1nc(Cl)cc(Cl)n1,,CC(=O)O,,O,,test
US20090156607A1,CCCC1CC(=O)N(Cc2cncn2C)C1.N#CBr>>CCCC1CC(=O)N(Cc2cnc(C#N)n2C)C1,CN(C)c1ccncc1,CN(C)C=O,,,,test
US20060111375A1,COc1cc2c(Oc3cc(C)c(C)cc3C(C)=O)ccnc2cc1OCc1ccccc1>>COc1cc2c(Oc3cc(C)c(C)cc3C(C)=O)ccnc2cc1O,,O=C(O)C(F)(F)F,,CS(=O)(=O)O,,test
US04675277,CC(=O)OC(C)=O.Nc1ccc(Cl)cc1[N+](=O)[O-]>>CC(=O)Nc1ccc(Cl)cc1[N+](=O)[O-],O=S(=O)(O)O,O,,,,test
US04427817,C1CCCCC1.Cc1ccc(S(=O)(=O)O)cc1.O=CC1CC2C=CC1C2.OCC1CC2C=CC1C2.c1ccc2ncccc2c1>>C1=CC2CC1CC2COC(OCC1CC2C=CC1C2)C1CC2C=CC1C2,,C1CCCCC1,,,,test
US05580865,BrCc1ccccc1.CO[C@H]1C(=S)N2C(C(=O)C(C)(C)C)=C(C)C(c3nnnn3C)S(=O)(=O)[C@H]12>>CO[C@H]1C(=S)N2C(C(=O)C(C)(C)C)=C(C)C(Cc3ccccc3)(c3nnnn3C)S(=O)(=O)[C@H]12,,CCOC(C)=O,CS(C)=O,CCN(CC)CC,,test
US20150307531A1,CC(C)P(Cl)C(C)C.COc1cccc(-n2c3ccccc3c3ccccc32)c1>>COc1cccc(-n2c3ccccc3c3ccccc32)c1P(C(C)C)C(C)C,,Cc1ccccc1,,,,test
US20060106020A1,CN(C)C=C(C(=O)c1ccc(F)cc1)c1ccnc(F)c1.NN>>Fc1ccc(-c2n[nH]cc2-c2ccnc(F)c2)cc1,,CCO,O,CCCCCC,CCOC(C)=O,test
US20070213359A1,ClCCCI.O=C(c1c[nH]c2ncccc12)C(F)(F)F>>O=C(c1cn(CCCCl)c2ncccc12)C(F)(F)F,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030139435A1,BrBr.CNC(=O)c1ccc(C)c(Nc2cc(NCC(C)(C)C)nc(NC)n2)c1>>CNC(=O)c1ccc(C)c(Nc2nc(NC)nc(NCC(C)(C)C)c2Br)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20120122780A1,CCOC(=O)CSc1onc(C)c1-c1cccc2ccccc12>>Cc1noc(SCC(=O)O)c1-c1cccc2ccccc12,,CO,,[Na+].[OH-],,test
US20110009454A1,N.Nc1nc(Cl)c(C(=O)NCc2ccc(Oc3ccccc3)cc2)cc1F>>Nc1nc(N)c(C(=O)NCc2ccc(Oc3ccccc3)cc2)cc1F,,O,,C1COCCO1,,test
US20150183801A1,CC(C)(C)OC(=O)N[C@@H]1CCN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2Br)C1.OB(O)c1cncnc1>>N[C@@H]1CCN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncnc2)C1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US06492360B1,COc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1C#CCCCc1ccccc1>>COc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1C=CCCCc1ccccc1,[Pd],C1CCOC1,,,,test
US20130196970A1,CC(C)(C)OC(=O)N[C@H]1CCN(C(=O)c2ccccc2)C1.CI>>CN(C(=O)OC(C)(C)C)[C@H]1CCN(C(=O)c2ccccc2)C1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20110190280A1,COCCNc1nc(-c2cccc(OC)c2)c(-c2ccnc(Cl)n2)s1.Nc1ccc(N2CCOCC2)c(Cl)c1>>COCCNc1nc(-c2cccc(OC)c2)c(-c2ccnc(Nc3ccc(N4CCOCC4)c(Cl)c3)n2)s1.Cl,,OCC(F)(F)F,,,,test
US06599917B1,CC(=O)O.CO[C@H]1CN(c2ccc(I)c(Cc3ccccc3)n2)C[C@@H]1OS(=O)(=O)c1cccc([N+](=O)[O-])c1>>CO[C@H]1CN(c2ccc(I)c(Cc3ccccc3)n2)C[C@@H]1OC(C)=O,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090042893A1,COC(OC)N(C)C.Cc1c[nH]c2ncnc(N3CCN(C(=NS(N)(=O)=O)Nc4cccc(Br)c4)[C@@H](C)C3)c12>>Cc1c[nH]c2ncnc(N3CCN(C(=NS(=O)(=O)N=CN(C)C)Nc4cccc(Br)c4)[C@@H](C)C3)c12,,CO,,,,test
US20070072853A1,CC(C)(C)C(=O)Cl.Nc1cc(NS(=O)(=O)c2ccccc2)ccc1NCC1CCOCC1>>CC(C)(C)c1nc2cc(NS(=O)(=O)c3ccccc3)ccc2n1CC1CCOCC1,CN(C)c1ccncc1,ClCCl,,,,test
US20130053555A1,O=S(=O)(Cl)c1ccccc1Br.c1ccc(-c2occ3c2[nH]c2ccccc23)cc1>>O=S(=O)(c1ccccc1Br)n1c2ccccc2c2coc(-c3ccccc3)c21,,C1CCOC1,,C1COCCOCCOCCOCCO1,[H-].[Na+],test
US20020132824A1,CC(=O)O.CC(C)(C)OC(=O)N1CC2CC(C1)c1cc(N)c(N)cc12>>Cc1nc2cc3c(cc2[nH]1)C1CC3CN(C(=O)OC(C)(C)C)C1,,CCO,,,,test
US20050245563A1,COC(=O)CCCBr.Cc1nn(C2CCCCO2)c2c1c(=O)[nH]c1ccc(Br)cc12>>COC(=O)CCCn1c(=O)c2c(C)nn(C3CCCCO3)c2c2cc(Br)ccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100056515A1,CN1C(=O)c2cccc(O)c2C1=O>>CN1Cc2cccc(O)c2C1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20030052304A1,OC/C=C/c1ccccc1.[K+].[OH-]>>O=C([O-])C=Cc1ccccc1.[K+],,Cc1ccccc1,,,,test
US05811433,CCOC(=O)c1cn(CCF)c2c(Cl)c(Cl)ncc2c1=O>>O=C(O)c1cn(CCF)c2c(Cl)c(Cl)ncc2c1=O,,CC(=O)O,,O,O=S(=O)(O)O,test
US20130196993A1,CCC/C=C/C(=O)Cl.COc1cc(NCCN)c2ccccc2n1>>CCCC=C(CCNc1cc(OC)nc2ccccc12)C(N)=O,,ClCCl,,CCN(CC)CC,,test
US20120214767A1,COc1ccc2c(c1)CCc1c-2noc1-c1onc(-c2ccccc2)c1C(F)(F)F>>Oc1ccc2c(c1)CCc1c-2noc1-c1onc(-c2ccccc2)c1C(F)(F)F,,ClCCl,,,,test
US20030195176A1,CCC(O)(CC)COCC1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>CCC(O)(CC)COCC1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150307520A1,C[Si](C)(C)C#Cc1ccn2nc([C@@H]3CCN3c3ncnc4[nH]cc(C#N)c34)n(-c3ccccc3)c(=O)c12>>C#Cc1ccn2nc([C@@H]3CCN3c3ncnc4[nH]cc(C#N)c34)n(-c3ccccc3)c(=O)c12,,CN(C)C=O,O,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20160244437A1,CON(C)C(=O)c1ccc(F)c(-c2cccc(C[C@H](NC(=O)[C@@H]3CC[C@@H](CNC(=O)OC(C)(C)C)CC3)C(=O)Nc3ccc(-c4nnn[nH]4)cc3)c2)c1.Cl>>CON(C)C(=O)c1ccc(F)c(-c2cccc(C[C@H](NC(=O)[C@@H]3CC[C@@H](CN)CC3)C(=O)Nc3ccc(-c4nnn[nH]4)cc3)c2)c1.Cl,,C1COCCO1,,CC#N,,test
US20130345196A1,NCc1cccc2ccccc12.O=S(=O)(Cl)c1cc(Cl)c(Cl)s1>>O=S(=O)(NCc1cccc2ccccc12)c1cc(Cl)c(Cl)s1,,ClCCl,O,CCN(CC)CC,,test
US20080214553A1,CC(C)NC(=O)CN.O=c1[nH]c2ccc(O)cc2c(=O)o1>>CC(C)NC(=O)CNC(=O)c1cc(O)ccc1N,,CC#N,ClCCl,,,test
US20150353507A1,CC(C)(C)OC(=O)Cc1ccc(N(C(=O)OC(C)(C)C)c2nc(Cl)nc3c2CCC3)cc1.OB(O)c1ccc(F)c(F)c1>>CC(C)(C)OC(=O)Cc1ccc(N(C(=O)OC(C)(C)C)c2nc(-c3ccc(F)c(F)c3)nc3c2CCC3)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US04058529,CNCCN.O=C(O)c1ccccc1C(=O)c1ccccc1>>CN1CCN2C(=O)c3ccccc3C12c1ccccc1,,Clc1ccccc1,,,,test
US20150119385A1,COC(OC)c1nc2c(cc1Br)CCCN2.O=C(Oc1ccccc1)Oc1ccccc1>>COC(OC)c1nc2c(cc1Br)CCCN2C(=O)Oc1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20110224208A1,COc1cc2c(cc1OC)C(C(Cl)(Cl)Cl)OC2=O>>COc1cc(C=C(Cl)Cl)c(C(=O)O)cc1OC,[Zn],CC(=O)O,,,,test
US20010039344A1,CCOC(=O)c1csc(NC(=O)C(CC2CCCC2)c2ccc([N+](=O)[O-])cc2)n1>>COC(=O)c1csc(NC(=O)C(CC2CCCC2)c2ccc([N+](=O)[O-])cc2)n1,,CO,,O=S(=O)(O)O,,test
US20100029650A1,CS(=O)(=O)c1ccc(-c2ccc(OCC3CCN(C#N)CC3)cn2)cc1.[N-]=[N+]=[N-]>>CS(=O)(=O)c1ccc(-c2ccc(OCC3CCN(c4nnn[nH]4)CC3)cn2)cc1,,CN(C)C=O,,[Cl-].[NH4+],,test
US04070178,CC(Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1)C(N)=O>>CC(C#N)Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1,,Cc1ccccc1,,O=P(Cl)(Cl)Cl,,test
US20100292208A1,CS(=O)(=O)Cl.c1cnc2nc(Oc3ccc4c(CN5CCNCC5)coc4c3)sc2c1>>CS(=O)(=O)N1CCN(Cc2coc3cc(Oc4nc5ncccc5s4)ccc23)CC1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20020028834A1,CC(C)(C)OC(=O)N1CCC(CI)CC1.COc1ccc2c(C)noc2c1>>COc1ccc2c(CCC3CCN(C(=O)OC(C)(C)C)CC3)noc2c1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20090247526A1,CCOC(=O)c1ccc(Cl)c(Oc2cc(NC(=S)NC(=O)c3ccccc3)ncc2Br)c1>>CCOC(=O)c1ccc(Cl)c(Oc2cc(NC(N)=S)ncc2Br)c1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US05843957,CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(C#CCNC(=O)OC(C)(C)C)c2)c2cccnc21>>CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(C#CCN)c2)c2cccnc21,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20060183732A1,C=CC[C@H](NC(=O)OCc1ccccc1)C(=O)O.CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)CC=C[C@H]1c1ccccc1>>C=CC[C@H](NC(=O)OCc1ccccc1)C(=O)N(C)C(C=C)c1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20090111809A1,CC(C)[Si](OC1CCN(N2CC[C@@H](Cc3c(Cl)cc(-c4ccc(C(=O)N5CCOCC5)cc4)cc3Cl)C2=O)CC1)(C(C)C)C(C)C>>O=C(c1ccc(-c2cc(Cl)c(C[C@@H]3CCN(N4CCC(O)CC4)C3=O)c(Cl)c2)cc1)N1CCOCC1,,C1CCOC1,,O,O=C(O)C(F)(F)F,test
US05100900,Cc1cccc2ccc(-c3ccccc3)nc12.O=[Se]=O>>O=Cc1cccc2ccc(-c3ccccc3)nc12,,ClCCl,,,,test
US20070244173A1,Cc1nc2c3c(ccc2n1C)[C@@H](OCC(F)F)[C@H](OC(=O)C(C)(C)C)[C@@H](c1ccccc1)O3>>Cc1nc2c3c(ccc2n1C)[C@@H](OCC(F)F)[C@H](O)[C@@H](c1ccccc1)O3,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20150344407A1,CCOC(=O)C=C1c2ccccc2C=Cc2ccccc21>>OCC=C1c2ccccc2C=Cc2ccccc21,,ClCCl,,CCCCCC,,test
US05082841,C1COCCN1.CCCC(=O)c1cnc2c(C3CO3)cccc2c1Nc1ccccc1C>>CCCC(=O)c1cnc2c(C(O)CN3CCOCC3)cccc2c1Nc1ccccc1C,,C1COCCO1,,,,test
US20010056142A1,CCO[Si](CCCS)(OCC)OCC.O=C1c2ccccc2C(=S)N1C1CCCCC1>>O=C1NC(=O)c2ccccc21,,ClC(Cl)Cl,,,,test
US20120157436A1,CN(C)/C=N/C(=S)c1nnc2n1CCN(C(=O)OC(C)(C)C)C2>>CC(C)(C)OC(=O)N1CCn2c(nnc2-c2ncns2)C1,,CCO,CO,c1ccncc1,,test
US04602014,CCOC(=O)c1cnc2c(c1Cl)CCC2.NNc1ccc(Cl)cc1>>O=c1c2c[nH]c3c(c-2nn1-c1ccc(Cl)cc1)CCC3,,CCCCO,,,,test
US07087597B1,CS(=O)(=O)Cl.OCc1ccc2c(c1)CCO2>>ClCc1ccc2c(c1)CCO2,,ClCCl,,CCN(CC)CC,,test
US20150238473A1,BrCCc1ccc(Br)cc1.OC(c1ccccc1)(c1ccccc1)C1CCNCC1>>OC(c1ccccc1)(c1ccccc1)C1CCN(CCc2ccc(Br)cc2)CC1,,O,,CC#N,,test
US04822801,CCn1cc(C(=O)O)c(=O)c2c(N)c(F)c(N3CCC(NC(=O)OC(C)(C)C)C3)c(F)c21.Cl>>CCn1cc(C(=O)O)c(=O)c2c(N)c(F)c(N3CCC(N)C3)c(F)c21.Cl,,CC(=O)O,,,,test
US20100204196A1,COc1cc2c(cc1[N+](=O)[O-])N(C(=O)CCN(C)C)CCC2>>COc1cc2c(cc1N)N(C(=O)CCN(C)C)CCC2,[Pd],CO,,[H][H],,test
US20090247577A1,CC(C)N(C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1Cc1ccccc1)C(=O)C1CC(=O)Nc2ccccc21>>CC(C)N(C[C@@H]1CNC[C@H]1Cc1ccccc1)C(=O)C1CC(=O)Nc2ccccc21,,O,,CC#N,CC#N,test
US20080096895A1,C1CNCCN1.Clc1ccc(-c2ccccn2)cn1>>c1ccc(-c2ccc(N3CCNCC3)nc2)nc1,,CC#N,,,,test
US20070208007A1,CCOC(=O)C(=O)CBr.Nc1ccc(C=O)cn1>>CCOC(=O)c1cn2cc(C=O)ccc2n1,,CCO,,,,test
US20100113502A1,C=CCn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C(=O)C(C)(F)F)CC2>>CCCn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C(=O)C(C)(F)F)CC2,[Pd],CO,,,,test
US20090105275A1,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(C(F)(F)F)n2)c1>>CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCC(C(F)(F)F)N2)c1,O=[Pt],CO,,C1COCCO1,Cl,test
US20100113774A1,COc1cc(OC)c(NC(=O)Cn2c(=O)n(CC(=O)OC(C)(C)C)c(=O)c3ncccc32)cc1Cl>>COc1cc(OC)c(NC(=O)Cn2c(=O)n(CC(=O)O)c(=O)c3ncccc32)cc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100305135A1,CC1(C)O[C@@H]2CC[C@@H](c3cnc4c(Cl)nccn34)[C@@H]2O1.N>>CC1(C)O[C@@H]2CC[C@@H](c3cnc4c(N)nccn34)[C@@H]2O1,,CC(C)O,,,,test
US04855378,C=CCC1CC(=O)OC1=O.c1ccncc1>>C=CCC1CC(=O)N(CC=C)C1=O,,CCOCC,,[Na],,test
US20040132994A1,CCOC(=O)CC(=O)Nc1cnn(C)c1N.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)CC(=O)Nc1cnn(C)c1NC(c1ccccc1)(c1ccccc1)c1ccccc1,,CN(C)C=O,,CCN(CC)CC,,test
US04810708,C1=C(N2CCCC2)CCC1.O=C(Cl)c1cccnc1Cl>>O=C(C1=C(N2CCCC2)CCC1)c1cccnc1Cl,,ClC(Cl)Cl,,CCN(CC)CC,,test
US05541229,CCC(C)Cc1nc2cc(C)c(C)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCC(C)Cc1nc2cc(C)c(C)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140128374A1,Cc1cc(Cl)c(C=O)c(Cl)n1.NN>>Cc1cc2[nH]ncc2c(Cl)n1,,ClCCCl,,O,,test
US20050054710A1,CC(=O)Nc1ccc(C(O)=C2C(=O)N(C(C)=O)c3ccccc32)cc1[N+](=O)[O-].ClP(Cl)(Cl)(Cl)Cl>>CC(=O)Nc1ccc(C(Cl)=C2C(=O)N(C(C)=O)c3ccccc32)cc1[N+](=O)[O-],,C1COCCO1,,,,test
US05627193,CC(C)c1ccccc1-c1cc(C(=O)NC(=N)N)c2ccccc2n1.CS(=O)(=O)O>>CC(C)c1ccccc1-c1cc(C(=O)NC(=N)N)c2ccccc2n1.CS(=O)(=O)O,,CCO,,CCOCC,,test
US20150087646A1,CC(C)(C)OC(=O)NNc1ccc(C(F)(F)F)cc1.COc1cc(Cl)c(C(=O)N=C=O)cc1CNC(=O)C(F)(F)F>>COc1cc(Cl)c(-c2nn(-c3ccc(C(F)(F)F)cc3)c(=O)[nH]2)cc1CNC(=O)C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070197478A1,CCOC(=O)Nc1cc(C(F)(F)F)nc(Cl)c1[N+](=O)[O-].NCc1ccccc1>>CCOC(=O)Nc1cc(C(F)(F)F)nc(NCc2ccccc2)c1[N+](=O)[O-],,C1CCOC1,,CCN(CC)CC,,test
US20040106635A1,CCC(=O)Br.CCOC(=O)C1(C(=O)OCC)CCC2(NCCc3cc(OC)c(OC)cc32)C(C2c3cc(OC)c(OC)cc3CCN2CC)C1>>CCOC(=O)C1(C(=O)OCC)CCC2(c3cc(OC)c(OC)cc3CCN2C(=O)CC)C(C2c3cc(OC)c(OC)cc3CCN2CC)C1,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20130030012A1,CN1CCCn2c1cc(Cl)nc2=O.O=C(O)C(F)(F)F.OCc1cc(F)c(F)c(F)c1>>CN1CCCn2c1cc(OCc1cc(F)c(F)c(F)c1)nc2=O.O=C(O)C(F)(F)F,,CN(C)C=O,,[H-].[Na+],,test
US20060084645A1,C1COCCN1.FC(F)(F)Oc1ccc(Nc2cc(Cl)nc(Cl)n2)cc1>>FC(F)(F)Oc1ccc(Nc2cc(Cl)nc(N3CCOCC3)n2)cc1,,CCO,,CCN(CC)CC,,test
US20120165318A1,CC1CCCNC1.COC(=O)c1ccc2nc(-c3ccc(F)cc3)c(Cl)nc2c1>>CC1CCCN(c2nc3cc(C(=O)O)ccc3nc2-c2ccc(F)cc2)C1,,CS(C)=O,,,,test
US20110039840A1,Cc1ccc(CCN2CCC3(CC2)CC(=O)c2cc(/C=C/C(=O)O)ccc2O3)cc1.NOC1CCCCO1>>Cc1ccc(CCN2CCC3(CC2)CC(=O)c2cc(/C=C/C(=O)NOC4CCCCO4)ccc2O3)cc1,,ClCCl,,,,test
US20100152190A1,COC(=O)c1cc(OC)c(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)cc1F>>COc1cc(C(=O)O)c(F)cc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F,,CO,,C1CCOC1,[Na+].[OH-],test
US05804588,C=CC=O.COc1c(N)cccc1F>>COc1c(F)ccc2cccnc12,,Clc1ccccc1Cl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20070259886A1,CC(C)c1cc(C(=O)N2Cc3ccc(O)cc3C2)c(OCc2ccccc2)cc1OCc1ccccc1.CN(C)CCCl>>CC(C)c1cc(C(=O)N2Cc3ccc(OCCN(C)C)cc3C2)c(OCc2ccccc2)cc1OCc1ccccc1,,CCOC(C)=O,CN(C)C=O,Cl,O=C([O-])[O-].[K+].[K+],test
US04386031,COC(=O)CCCCCCCCCCN(C(=O)c1ccc(Cl)cc1)c1ccc(OC)cc1>>COc1ccc(N(CCCCCCCCCCC(=O)O)C(=O)c2ccc(Cl)cc2)cc1,,CO,,[Na+].[OH-],,test
US20140031336A1,CCOC(=O)c1ccc(-c2ccc3c(c2)[C@H](Nc2ccc([N+](=O)[O-])cn2)C[C@H](C)N3C(C)=O)nc1>>CCOC(=O)c1ccc(-c2ccc3c(c2)[C@H](Nc2ccc(N)cn2)C[C@H](C)N3C(C)=O)nc1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20150376611A1,CO[C@@H]1[C@@H]2O[Si](C(C)C)(C(C)C)O[Si](C(C)C)(C(C)C)OC[C@H]2O[C@H]1n1cnc2c(/C=C/c3ccccc3)ncnc21>>CO[C@@H]1[C@@H](O)[C@@H](CO)O[C@H]1n1cnc2c(/C=C/c3ccccc3)ncnc21,,C1CCOC1,,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US06291455B1,COCCOc1cc2ncnc(Cl)c2cc1OC.Cc1ccc(N)c(F)c1>>COCCOc1cc2ncnc(Nc3ccc(C)cc3F)c2cc1OC.Cl,,CC(C)O,,,,test
US20160272592A1,COC(=O)C1(F)CCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CCC(F)(CO)C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20050043336A1,Fc1cccc2ncnc(Cl)c12.Nc1ccc(OCc2cccc(F)c2)c(Cl)c1>>Fc1cccc(COc2ccc(Nc3ncnc4cccc(F)c34)cc2Cl)c1,,CC(C)O,,CCN(C(C)C)C(C)C,Cl,test
US20130150343A1,CC(C)CCON=O.Cc1ccc(-c2cnc(C(C)(C)C)[nH]2)cc1>>Cc1ccc(-c2[nH]c(C(C)(C)C)nc2N=O)cc1,,C1CCCCC1,C1CCOC1,CCOC(C)=O,,test
US05025036,CCCc1c(OCCCCCC(=O)c2c(C)c(C)c(OC)c(OC)c2C)ccc(C(=O)O)c1O>>CCCc1c(OCCCCCC(=O)c2c(C)c(C)c(O)c(O)c2C)ccc(C(=O)O)c1O,,ClCCl,,BrB(Br)Br,,test
US20090155299A1,CC(=O)C(=O)[C@@](O)(C(C)=O)[C@](O)(C(C)=O)[C@](O)(C(C)=O)[C@@H](C)O.COc1ccc(O)cc1>>COc1ccc([C@]2(C)O[C@@](O)(C(C)=O)[C@@](O)(C(C)=O)[C@](O)(C(C)=O)[C@]2(O)C(C)=O)cc1,,ClCCl,,CCOCC,FB(F)F,test
US20110274657A1,C=CC(=O)OC.N#Cc1ccc(S(N)(=O)=O)cc1>>COC(=O)CCNS(=O)(=O)c1ccc(C#N)cc1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20140206681A1,CCOc1cc(C(=O)OC)ccc1Br>>CCOc1cc(C(=O)O)ccc1Br,,C1CCOC1,O,CO,[Li+].[OH-],test
US20140005184A1,CC(O)C1(N)CC1.CCOC(=O)CC(=O)c1cc(F)c(F)c(F)c1F.CCOC(OCC)OCC>>CCOC(=O)C(=CNC1(CCO)CC1)C(=O)c1cc(F)c(F)c(F)c1F,,Cc1ccccc1,,CC(=O)OC(C)=O,,test
US20160185785A1,Clc1ncnc2[nH]ccc12.Fc1ccc(I)cc1>>Fc1ccc(-n2ccc3c(Cl)ncnc32)cc1,,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=C([O-])[O-].[K+].[K+],test
US04556715,O=C(Cl)c1cccnc1.OCc1ccc(OCCCCc2ccc(Cl)cc2)cc1>>O=C(OCc1ccc(OCCCCc2ccc(Cl)cc2)cc1)c1cccnc1,,c1ccccc1,,CCN(CC)CC,Cl,test
US20050209284A1,COC(=O)c1ccc(C=O)s1.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>COC(=O)c1ccc(-c2cnco2)s1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US05189211,COC(=O)COc1c(F)cc(SCCNS(=O)(=O)c2ccc(Cl)cc2)cc1F.N>>NC(=O)COc1c(F)cc(SCCNS(=O)(=O)c2ccc(Cl)cc2)cc1F,,CO,,,,test
US20090036450A1,CCOC(=O)CC(=O)CNC(=O)OCc1ccccc1.O=N[O-]>>CCOC(=O)C(=NO)C(=O)CNC(=O)OCc1ccccc1,,CC(=O)O,,O,,test
US20080176843A1,O=C1CCCCCC1.O=C1Nc2ccccc2C2(CCNCC2)O1>>O=C1Nc2ccccc2C2(CCN(C3CCCCCC3)CC2)O1,,ClCCCl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20050014748A1,NCC1CCN(C(c2ccccc2)c2ccccc2)C1.O=C=NC(c1ccccc1)c1ccccc1>>O=C(NCC1CCN(C(c2ccccc2)c2ccccc2)C1)NC(c1ccccc1)c1ccccc1,,ClCCl,,,,test
US20140163035A1,C=O.COC(=O)Cc1ccc(Cl)cc1Cl>>COC(=O)C(CO)c1ccc(Cl)cc1Cl,,CS(C)=O,,O=C([O-])O.[Na+],,test
US20030073840A1,COCCl.COc1nccc(I)c1CO>>COCOCc1c(I)ccnc1OC,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05707994,CCOC(=O)[C@H](CNC(=O)CCNC(=O)c1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)NS(=O)(=O)c1ccccc1>>CCOC(=O)[C@H](CNC(=O)CCNC(=O)c1ccc(C(=N)N)cc1)NS(=O)(=O)c1ccccc1,,O=C(O)C(F)(F)F,,,,test
US04980371,CCCCCCCCCCCCBr.c1ccoc1>>CCCCCCCCCCCCc1ccco1,,CCCCCC,CCOCC,[Li]CCCC,[Cl-].[NH4+],test
US20090137561A1,COC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(C2=CCCC2(C)C)c1.COc1cc(B(O)O)c(F)cn1>>COC(=O)c1ccc(-c2cc(OC)ncc2F)c(C2=CCCC2(C)C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20120028973A1,O=Cc1cnc(-c2ccc(OC(F)(F)F)cc2)nc1>>OCc1cnc(-c2ccc(OC(F)(F)F)cc2)nc1,,CO,,[BH4-].[Na+],,test
US20100280268A1,CCNc1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C(=O)OC)c2)ccc1N.Cc1ccc(S(=O)(=O)Cl)cc1>>CCNc1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C(=O)OC)c2)ccc1NS(=O)(=O)c1ccc(C)cc1,,ClCCl,,c1ccncc1,,test
US20120276018A1,O=C(CCl)c1ccccc1.O=C(N[C@H]1CN2CCC1CC2)OC(c1cccc(F)c1)c1cccc(F)c1>>O=C(N[C@H]1C[N+]2(CC(=O)c3ccccc3)CCC1CC2)OC(c1cccc(F)c1)c1cccc(F)c1.[Cl-],,CCOC(C)=O,,,,test
US20080249066A1,CCCCCCCCCCCCS[C@H](O)C(COC(c1ccccc1)(c1ccc(OC)cc1)c1ccc(OC)cc1)OCCCCCCCCCC>>CCCCCCCCCCCCSC[C@H](CO)OCCCCCCCCCC,,CO,ClC(Cl)Cl,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US06025350,COC1CN(C(=O)CNC(=O)OC(C)(C)C)Cc2ccccc21>>COC1CN(C(=O)CN)Cc2ccccc21,,CCOC(C)=O,Cl,,,test
US05610144,COC(=O)Cc1cccc(NC(=O)NCC(=O)N2C(C(=O)OC(C)(C)C)CCC2c2ccccc2)c1>>CC(C)(C)OC(=O)C1CCC(c2ccccc2)N1C(=O)CNC(=O)Nc1cccc(CC(=O)O)c1,,CO,O,[K+].[OH-],,test
US04898874,Cc1cccc(C(=O)c2ccc(Cl)cc2)c1N>>Cc1cccc2c(-c3ccc(Cl)cc3)onc12,,CC(=O)O,,OO,,test
US20030087775A1,CO.O=C(O)COC1CCCC1>>COC(=O)COC1CCCC1,,O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20160168139A1,Nc1ccc2c(c1)Cc1cccc(-c3cc(N4CCOCC4)cc(=O)[nH]3)c1O2.O=Cc1ccnc2c1NCCO2>>O=c1cc(N2CCOCC2)cc(-c2cccc3c2Oc2ccc(NCc4cncc5c4NCCO5)cc2C3)[nH]1,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05753682,COC1(c2cccc(O)c2)CCOCC1.OCc1ccc(-n2ccnc2)cc1>>COC1(c2cccc(OCc3ccc(-n4ccnc4)cc3)c2)CCOCC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04093644,C=CC#N.Cc1cc(OC(F)(F)C(Cl)Cl)c([N+](=O)[O-])cc1S(=O)(=O)Cl>>Cc1cc(OC(F)(F)C(Cl)Cl)c([N+](=O)[O-])cc1S(=O)(=O)C=CC#N,,CC#N,,CCN(CC)CC,Cl,test
US20120107275A1,COc1ncc2c(=O)cc[nH]c2c1Br.O=C(O)C(=O)CBr.O=C1Nc2ccc(I)cc2C1=O>>O=C(O)c1c(O)cnc2ccc(I)cc12,,O,,Cl,[K+].[OH-],test
US20080167287A1,COC(=O)c1ccc(C(C)=O)cc1F.CS(C)=O>>COC(=O)c1ccc(C(=O)C=O)cc1F,,CS(C)=O,,Br,O,test
US20040106653A1,CC(C)(C)OC(=O)N(CCc1ccc(S(=O)(=O)c2ccc(Oc3ccccc3C(=O)O)cc2)cc1)Cc1ccccc1.CCI>>CCOC(=O)c1ccccc1Oc1ccc(S(=O)(=O)c2ccc(CCN(Cc3ccccc3)C(=O)OC(C)(C)C)cc2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040045896A1,CCCCCCCCCCCCOc1cc(C(=O)OCC)cc(OCCCCCCCCCCCC)c1OCCCCCCCCCCCC>>CCCCCCCCCCCCOc1cc(C(=O)O)cc(OCCCCCCCCCCCC)c1OCCCCCCCCCCCC,,CCO,,Cl,[K+].[OH-],test
US20100048636A1,Br[Mg]CCCC[Mg]Br.COC(=O)CC[C@H]1COC(C)(C)N1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1[C@@H](CCC2(O)CCCC2)COC1(C)C,,C1CCOC1,,,,test
US20100063038A1,Cc1cc(N)c(F)cc1Br.O=C=Nc1cc(C(F)(F)F)ccc1F>>Cc1cc(NC(=O)Nc2cc(C(F)(F)F)ccc2F)c(F)cc1Br,,C1CCOC1,,CCOCC,,test
US20100216814A1,Brc1ccoc1.C#Cn1c2c(c3cc(C)ccc31)CN(C)CC2>>Cc1ccc2c(c1)c1c(n2C#Cc2ccoc2)CCN(C)C1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20160052924A1,N#CNc1ccccc1>>N=CNc1ccccc1,,CCOCC,Cl,,,test
US20140243372A1,C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@H](c2ccc(Cl)cc2)OC1=O.N[C@H](CO)C1CC1>>C=CC[C@@](C)(C[C@H](c1cccc(Cl)c1)C(O)c1ccc(Cl)cc1)C(=O)N[C@H](CO)C1CC1,,CC(=O)OC(C)C,,Cl,,test
US20040180886A1,C=CC(C)(C)C/C=C(\NC(=O)OCc1ccccc1)C(=O)OC.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CCC(C)(C)CCC(NC(=O)OC(C)(C)C)C(=O)OC,[Pd],CO,,[H][H],,test
US20090286777A1,C=[N+]=[N-].C[C@@H](O[C@H]1CN(C(=O)OC(C)(C)C)[C@@H](CCC(=O)O)[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[C@@H](O[C@H]1CN(C(=O)OC(C)(C)C)[C@@H](CCC(=O)C=[N+]=[N-])[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,C1CCOC1,,CC(C)COC(=O)Cl,CCN(CC)CC,test
US20070043010A1,COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C.Oc1ccc2c(Cl)ncnc2c1>>COC(=O)[C@@H]1C[C@H](Oc2ccc3c(Cl)ncnc3c2)CN1C(=O)OC(C)(C)C,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05342546,CCCCCC1C=CC(=O)CC1.CCCc1ccc(Br)cc1>>CCCCCC1=CCC(O)(c2ccc(CCC)cc2)CC1,,CCOCC,,Cl,[Mg],test
US20090088406A1,CC(C)(C)OC(=O)N1CC[C@H](Nc2ccc(F)c(Cl)c2)C1.ClCCCBr>>CC(C)(C)OC(=O)N1CC[C@H](N(CCCCl)c2ccc(F)c(Cl)c2)C1,,CCOC(C)=O,CN1CCCC1=O,O,O=C([O-])[O-].[K+].[K+],test
US03988363,Cc1cc(C(C)(C)C)c(O)c(C)c1CCl.[C-]#N>>Cc1cc(C(C)(C)C)c(O)c(C)c1CC#N,,CN(C)C=O,,O,,test
US20130079313A1,COc1ccc(C(=O)OCC(=O)O)cc1N(CC(N)=O)S(C)(=O)=O.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>COc1ccc(C(=O)OCC(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1N(CC(N)=O)S(C)(=O)=O,CN(C)c1ccncc1,CN(C)C=O,O,ClCCCl,,test
US20110275637A1,C1COCCN1.Cc1ncccc1COC(=O)Oc1ccc([N+](=O)[O-])cc1>>Cc1ncccc1COC(=O)N1CCOCC1,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US03933811,CNC.O=Cc1ccccn1.[C-]#N>>CN(C)C(C#N)c1ccccn1,,O,,Cl,,test
US20050171131A1,N#Cc1ccc(-c2c(N)nc(N)nc2COCc2ccccc2)cc1>>NCc1ccc(-c2c(N)nc(N)nc2COCc2ccccc2)cc1,[Ni],CO,N,[H][H],,test
US20110250137A1,COC(=O)[C@H](CC[C@H](CO[Si](C)(C)C(C)(C)C)N=[N+]=[N-])NC(=O)OC(C)(C)C>>COC(=O)[C@H](CC[C@H](CO)N=[N+]=[N-])NC(=O)OC(C)(C)C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130095193A1,CC(C)(C)OC(=O)NC(CF)c1ccc(C=O)cc1.NO>>CC(C)(C)OC(=O)NC(CF)c1ccc(C=NO)cc1,,CCO,,,,test
US05008267,COc1cc(CCCNCCO)ccc1[N+](=O)[O-].Cc1ccc(S(=O)(=O)O)cc1.Cn1c(N2CCCN(c3ccccc3[N+](=O)[O-])CC2)cc(=O)n(C)c1=O.O>>COc1cc(CCCN(CCO)CCNc2cc(=O)n(C)c(=O)n2C)ccc1[N+](=O)[O-].O=C(O)C(=O)O,,CC#N,,CO,ClC(Cl)Cl,test
US20080004271A1,N#Cc1c(O)nc(CC2CC2)nc1-c1ccc(Cl)c(Cl)c1.O=P(Cl)(Cl)Cl>>N#Cc1c(Cl)nc(CC2CC2)nc1-c1ccc(Cl)c(Cl)c1,,C1COCCO1,,,,test
US20060172983A1,COC(=O)COc1ccc(N=C=O)cc1.COC(=O)COc1ccc(NC(=O)OCCO)cc1>>COC(=O)COc1ccc(NC(=O)OCCOC(=O)Nc2ccc(OCC(=O)OC)cc2)cc1,,Cc1ccccc1,,,,test
US20040082583A1,Nc1cc(Oc2ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc2)ccc1[N+](=O)[O-]>>Nc1ccc(Oc2ccc(N)c(N)c2)cc1,[Pd],CCO,,,,test
US06380288B1,NNC(=O)c1ccccc1O.O=Cc1ccco1>>O=C(NN=Cc1ccco1)c1ccccc1O,,CO,,,,test
US20160200676A1,C=C[C@H](C(=O)N[C@@H](CCSC)C(=O)OC)[C@H](O)CCCC>>C=C[C@H](C(=O)N[C@@H](CCSC)C(=O)O)[C@H](O)CCCC,,C1CCOC1,O,[Li+].[OH-],,test
US20090197825A1,CCOC(=O)CCBr.Nc1nnc(S)n1-c1ccc(C2CC2)c2ccccc12>>CCOC(=O)CCSc1nnc(N)n1-c1ccc(C2CC2)c2ccccc12,,CN(C)C=O,,,,test
US06743795B1,Nc1ccc2cn[nH]c2c1.O=[N+]([O-])c1ccc(Cl)nc1Cl>>O=[N+]([O-])c1ccc(Cl)nc1Nc1ccc2cn[nH]c2c1,,CC#N,,CCN(CC)CC,O,test
US20070196270A1,CC(=O)Nc1cc(Cl)ccc1OCC(=O)N1CC2CN(C(=O)OC(C)(C)C)CC(C1)N2.Fc1ccc(CCl)cc1>>CC(=O)Nc1cc(Cl)ccc1OCC(=O)N1CC2CN(C(=O)OC(C)(C)C)CC(C1)N2Cc1ccc(F)cc1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20050070712A1,CCc1nc(N)nc(N)c1-c1ccc([N+](=O)[O-])cc1>>CCc1nc(N)nc(N)c1-c1ccc(N)cc1,[Pd],CC(=O)O,O,[Na+].[OH-],,test
US20090048223A1,CC(C)(C)OC(=O)N1CC[C@H](NC(=O)CBr)C1.OC1CCNC1>>CC(C)(C)OC(=O)N1CC[C@H](NC(=O)CN2CCC(O)C2)C1,,CC#N,ClC(Cl)Cl,O,O=C([O-])[O-].[K+].[K+],test
US20130190249A1,O=C(OCc1ccccc1)C1CC(F)(F)C1>>O=C(O)C1CC(F)(F)C1,[Pd],CCO,,,,test
US04507306,O=C(Cl)C1CC1.c1ccc([C@]23CCNC[C@H]2c2ccccc2O3)cc1>>O=C(C1CC1)N1CC[C@]2(c3ccccc3)Oc3ccccc3[C@@H]2C1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US05321135,COc1cc(C=O)cc(OC)c1O.O=[N+]([O-])c1ccc(CBr)cc1>>COc1cc(C=O)cc(OC)c1OCc1ccc([N+](=O)[O-])cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150175594A1,CCC1CCc2c(sc(N)c2-c2nc(C3CC3)no2)C1.O=C1OC(=O)C2=C1CCC2>>CCC1CCc2c(sc(NC(=O)C3=C(C(=O)O)CCC3)c2-c2nc(C3CC3)no2)C1,,CO,ClCCl,,,test
US20080181866A1,Nc1nc(-c2ccc(C(=O)Nc3cccnc3)cc2)cs1.O=C(OCc1ccccc1)C1COC2(CCOCC2)N1C(=O)O>>O=C(Nc1cccnc1)c1ccc(-c2csc(NC(=O)C3COC4(CCOCC4)N3C(=O)OCc3ccccc3)n2)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160075713A1,CC(C)(C)OC(=O)NC1CCNCC1.O=S(=O)(OCC(F)(F)c1ccc(C(F)(F)F)cn1)C(F)(F)F>>CC(C)(C)OC(=O)NC1CCN(CC(F)(F)c2ccc(C(F)(F)F)cn2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100305052A1,CC(=O)C(=Cc1ccc([N+](=O)[O-])cc1C(F)(F)F)C(C)=O.Nc1cc[nH]c(=O)c1>>CC(=O)C1=C(C)Nc2cc[nH]c(=O)c2C1c1ccc([N+](=O)[O-])cc1C(F)(F)F,,CC(C)O,,,,test
US20100113774A1,CC(C)(C)OC(=O)Cn1c(=O)[nH]c2ccnc(Cl)c2c1=O.COc1cc(OC)c(NC(=O)CBr)cc1Cl>>COc1cc(OC)c(NC(=O)Cn2c(=O)n(CC(=O)OC(C)(C)C)c(=O)c3c(Cl)nccc32)cc1Cl,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20150218131A1,CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(NC(=O)c3cnn(-c4ccc(OC(F)(F)F)cc4)c3)cc2)C1.Cl>>Cl.O=C(Nc1ccc([C@H]2CNCCO2)cc1)c1cnn(-c2ccc(OC(F)(F)F)cc2)c1,,C1COCCO1,,CCOCC,,test
US20160194328A1,CCCC(N)CCn1c(Sc2cc(Cl)cc(Cl)c2)nc2c(N)ncnc21.O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccc(N=C=S)cc21>>Nc1ncnc2c1nc(Sc1cc(Cl)cc(Cl)c1)n2CCCCCCNC(=S)Nc1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1,,CN(C)C=O,,CCN(CC)CC,,test
US03984467,CCCCC(=N)N.S=C=Nc1ccc(Cl)cc1>>CCCCC(=N)NC(=S)Nc1ccc(Cl)cc1,,CC(C)=O,,Cl,[Na],test
US20020045759A1,CCOC(=O)c1c[nH]c(S)n1.N#Cc1ccc(C(=O)CBr)cc1>>CCOC(=O)c1cnc(SCC(=O)c2ccc(C#N)cc2)[nH]1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100286164A1,C=C[Mg]Br.O=Cc1ccc2ccccc2c1>>C=CC(O)c1ccc2ccccc2c1,,C1CCOC1,,Cl,,test
US20130029969A1,NC(=O)c1sc(Br)cc1N.O=C(Cl)C1CCCCC1>>NC(=O)c1sc(Br)cc1NC(=O)C1CCCCC1,,O,,C1CCOC1,CCN(CC)CC,test
US20150291563A1,CC(C)(C)OC(=O)N1CC=C(c2cccc(C3CC(C(O)(C(F)(F)F)C(F)(F)F)=NN3c3ccccc3Cl)c2)CC1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.OC(C1=NN(c2ccccc2Cl)C(c2cccc(C3=CCNCC3)c2)C1)(C(F)(F)F)C(F)(F)F,,ClCCl,,,,test
US20120316161A1,CCCC(C(=O)OCC)c1c(C)nc2ccnn2c1N1CCC[C@H](NS(=O)(=O)c2ccc(Cl)cc2)C1>>CCCC(C(=O)O)c1c(C)nc2ccnn2c1N1CCC[C@H](NS(=O)(=O)c2ccc(Cl)cc2)C1,,CCO,,[Na+].[OH-],,test
US20100298377A1,CC(C)(C)OC(=O)n1ncc2cc(NC(=O)O[C@H](c3ccc(Cl)c(Cl)c3)[C@@H]3CCCCN3C(=O)[O-])ccc21>>O=C(Nc1ccc2[nH]ncc2c1)O[C@H](c1ccc(Cl)c(Cl)c1)[C@@H]1CCCCN1,,CO,,Cl,,test
US04344960,CC1(C)[C@@H](C=C(Cl)C(F)(F)C(F)(F)F)[C@@H]1C(=O)O.O=S(Cl)Cl>>CC1(C)[C@@H](C=C(Cl)C(F)(F)C(F)(F)F)[C@@H]1C(=O)Cl,,ClC(Cl)(Cl)Cl,,,,test
US05604213,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CCC2=O>>CC(C)(C)[Si](C)(C)OC1=CC2=CC[C@H]3[C@@H]4CCC(=O)[C@@]4(C)CC(=O)[C@@H]3[C@@]2(C)CC1,,ClCCl,,CCN(CC)CC,,test
US20040259904A1,COc1cc2c(cc1O)-c1c(c(-c3ccc(-c4ccc(OCOCC[Si](C)(C)C)cc4)cc3)nn1COCC[Si](C)(C)C)C2.O=S(=O)(Nc1ccccc1)C(F)(F)F>>COc1cc2c(cc1OS(=O)(=O)C(F)(F)F)-c1c(c(-c3ccc(-c4ccc(OCOCC[Si](C)(C)C)cc4)cc3)nn1COCC[Si](C)(C)C)C2,,C1CCOC1,,[H-].[Na+],,test
US20100222217A1,Cn1cc(C(=O)O)c(C(F)(F)F)n1.Nc1ccccc1OC(F)(F)C(F)C(F)(F)F>>Cn1cc(C(=O)Nc2ccccc2OC(F)(F)C(F)C(F)(F)F)c(C(F)(F)F)n1,,ClCCl,,CCN(CC)CC,O=C1OCCN1P(=O)(Cl)N1CCOC1=O,test
US20020193367A1,CNC.Cc1cc([N+](=O)[O-])c(NC(=O)OC(C)(C)C)cc1Cl>>Cc1cc([N+](=O)[O-])c(NC(=O)OC(C)(C)C)cc1N(C)C,,CS(C)=O,,,,test
US20090198063A1,CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)C1CCN(CCn2c(=O)cnc3ccc(F)nc32)CC1.Cl>>Cl.O=c1cnc2ccc(F)nc2n1CCN1CCC(NCc2cc3c(cn2)OCCO3)CC1,,CO,,CCOC(C)=O,,test
US20150259328A1,CN(C)C(=O)Cl.NC(=O)c1cnc(Nc2ccc(C3CCNCC3)cc2)nc1NC1CC1>>CN(C)C(=O)N1CCC(c2ccc(Nc3ncc(C(N)=O)c(NC4CC4)n3)cc2)CC1,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US20020173517A1,CCC(CC)(C(=O)[O-])C(=O)[O-].CCO.Cc1c(Cl)ccnc1C(C=O)C1CC1>>CCOC(=O)c1cc(C2CC2)c2c(C)c(Cl)ccn2c1=O,,CCO,,C1CCNCC1,CC(=O)O,test
US20120115813A1,O=Cc1cc(Cl)cc(OCCCOCc2ccccc2)c1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=Cc1cc(Cl)cc(OCCCOCc2ccccc2)c1OS(=O)(=O)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US05922882,C=O.CCNCC.OCCCc1ccc(O)c(-n2nc3ccccc3n2)c1>>CCN(CC)Cc1cc(CCCO)cc(-n2nc3ccccc3n2)c1O,,CCCCO,,,,test
US20060160876A1,CCc1c(Br)ccc2c3c([nH]c12)C(CC)(CC(=O)O)OCC3>>CCc1c(Br)ccc2c3c([nH]c12)C(CC)(CCO)OCC3,,C1CCOC1,C1CCOC1,,,test
US20100152468A1,NC(=O)CC1=CCc2c(Br)c(Br)c3c(c21)CCO3>>NC(=O)C[C@@H]1CCc2c(Br)c(Br)c3c(c21)CCO3,,CCO,,[H][H],,test
US20160152608A1,Cc1cc2nc(-c3cccc(C(F)F)c3)[nH]c2cc1Nc1nc(-c2cccnc2)cs1.O=Cc1cccc(OC(F)(F)F)c1>>Cc1cc2nc(-c3cccc(OC(F)(F)F)c3)n(C)c2cc1Nc1nc(-c2cccnc2)cs1,,CN(C)C=O,,O=S([O-])O.[Na+],,test
US20040038986A1,CCCOC(=O)Cl.O=[N+]([O-])c1ccc(O)cc1>>CCCOC(=O)Oc1ccc([N+](=O)[O-])cc1,,C1CCOC1,,CCN(CC)CC,O,test
US20040147748A1,CS(=O)(=O)Nc1ccc(N)nc1.CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)O)cc1Cl>>CS(=O)(=O)Nc1ccc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(C)(=O)=O)c(Cl)c2)nc1,CN(C)C=O,C1CCOC1,ClCCl,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20130211145A1,C=CCc1c(O)cccc1C=O.COc1ccc(CCl)cc1>>C=CCc1c(C=O)cccc1OCc1ccc(OC)cc1,,CC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20120202785A1,CCN.O=[N+]([O-])c1ccc(F)c(-c2ccccn2)c1F>>CCNc1c([N+](=O)[O-])ccc(F)c1-c1ccccn1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20070232645A1,CCCc1ccc2c(Nc3cc(C)ccc3Sc3ccc(O)cc3)ccnc2n1.CS(=O)(=O)Cl>>CCCc1ccc2c(Nc3cc(C)ccc3Sc3ccc(OS(C)(=O)=O)cc3)ccnc2n1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US06103718,COc1ccc(C2=NN(CCBr)C(=O)[C@H]3CCCC[C@@H]23)cc1OC.Cl.c1c[nH]cn1>>COc1ccc(C2=NN(CCn3ccnc3)C(=O)[C@H]3CCCC[C@@H]23)cc1OC.Cl,,CO,,,,test
US20120122764A1,CC(C)(C)OC(=O)C(CNC(=O)C1(CC(=O)OCc2ccccc2)CCCC1)Cc1ccc(Cl)c(Cl)c1>>CC(C)(C)OC(=O)C(CNC(=O)C1(CC(=O)O)CCCC1)Cc1ccc(Cl)c(Cl)c1,[Pd],CCO,,,,test
US20100137281A1,CCc1cc(C(=O)OC)c(N)s1.NCCc1cccs1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCc1cc2c(=O)n(CCc3cccs3)c(=O)[nH]c2s1,,ClCCl,,CCN(CC)CC,,test
US20080058328A1,CN1Cc2c(Cl)cc(Cl)cc2[C@H](c2ccccc2N)C1.COC(=O)C(C)(C)N=C=O.ClCCl>>CN1Cc2c(Cl)cc(Cl)cc2[C@H](c2ccccc2N2C(=O)NC(C)(C)C2=O)C1.Cl,,ClCCl,,O,,test
US20070244186A1,COc1ccc2sc(C(=O)N3CCOCC3)nc2c1[N+](=O)[O-]>>COc1ccc2sc(C(=O)N3CCOCC3)nc2c1N,[Pd],CO,,,,test
US20160096833A1,CC(C)[Si](OCc1cc(Br)cn2ncnc12)(C(C)C)C(C)C>>OCc1cc(Br)cn2ncnc12,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080207654A1,CCCCc1nc(C)n(Cc2cscn2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nc(C)n(Cc2cscn2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20100152183A1,NS(=O)(=O)c1ccc(F)c([N+](=O)[O-])c1.OCC1COCCO1>>NS(=O)(=O)c1ccc(OCC2COCCO2)c([N+](=O)[O-])c1,,C1CCOC1,,[H-].[Na+],,test
US09353063B2,CC1(C)C=C(C(=O)c2ccc3cnccc3c2)C(C)(C)CC1>>CC1(C)C=C(C(=O)c2ccc3c(c2)CCNC3)C(C)(C)CC1,O=[Pt]=O,CC(=O)O,,,,test
US20140121367A1,CC(=O)O[C@H]1C(=O)[C@]2(C)[C@@H](O)C[C@H]3OC[C@@]3(OC(C)=O)[C@H]2[C@H](OC(=O)c2ccccc2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)c3ccccc3)c3ccccc3)C(C)=C1C2(C)C.O=C(Cl)c1cccnc1>>CC(=O)O[C@H]1C(=O)[C@]2(C)[C@@H](O)C[C@H]3OC[C@@]3(OC(C)=O)[C@H]2[C@H](OC(=O)c2ccccc2)[C@]2(O)C[C@H](OC(=O)[C@H](OC(=O)c3cccnc3)[C@@H](NC(=O)c3ccccc3)c3ccccc3)C(C)=C1C2(C)C,c1ccncc1,ClCCl,,Cl,,test
US06455520B1,Cc1ccc(N)cc1NC(=O)c1cccc(CN2CCN(C)CC2)c1.O=C(Cl)c1cccnc1>>Cc1ccc(NC(=O)c2cccnc2)cc1NC(=O)c1cccc(CN2CCN(C)CC2)c1,,ClCCl,,CCN(CC)CC,,test
US20070010528A1,CC(C)(C)OC(=O)N1CCNC(=O)C1.ClCCCSc1ccc2cc(Cl)ccc2c1>>CC(C)(C)OC(=O)N1CCN(CCCSc2ccc3cc(Cl)ccc3c2)C(=O)C1,,CN(C)C=O,,O,[H-].[Na+],test
US20100087471A1,Cc1ncc(C#C[Si](C)(C)C)cn1>>C#Cc1cnc(C)nc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20140243345A1,CC(C)(C)OC(=O)N1CCNCC1.Nc1cc(F)ccc1[N+](=O)[O-]>>CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)[O-])c(N)c2)CC1,,CN(C)C=O,,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20130274266A1,C[Si](C)(C)CCOCn1cc(C(F)(F)F)nc1C=O.NO>>C[Si](C)(C)CCOCn1cc(C(F)(F)F)nc1C=NO,,O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US06278028B1,CCCCCCCCOC(=O)c1ccc(-c2ccc(O)cc2)cc1.CCCCCCCCOC(=O)c1ccc(-c2ccc(OC(=O)c3ccc(OC[C@@H](C)CC)c([N+](=O)[O-])c3)cc2)cc1>>CCCCCCCCOC(=O)c1ccc(-c2ccc(OC(=O)c3ccc(O[C@H](C)CCCCCC)cc3)cc2)cc1,CN(C)c1ccncc1,,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20100137281A1,CCc1cc2c(=O)n(CC(=O)c3ccc(OC)cc3)c(=O)n(Cc3ccc(-c4ccccc4C#N)c(F)c3)c2s1.O=C([O-])O.[NH3+]O>>CCc1cc2c(=O)n(CC(=O)c3ccc(OC)cc3)c(=O)n(Cc3ccc(-c4ccccc4-c4noc(=O)[nH]4)c(F)c3)c2s1,,ClC(Cl)Cl,,CS(C)=O,[Cl-].[Na+],test
US05688795,c1ccc(CN2CCN(c3ccccc3-c3ncco3)CC2)cc1>>c1ccc(N2CCNCC2)c(-c2ncco2)c1,[Pd],CO,,,,test
US20120094964A1,O=[N+]([O-])c1ccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)cc1>>Nc1ccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)cc1,[Pt],CO,,,,test
US20110092459A1,CCOC(OCC)[C@H](C)N.O=Cc1cccc2ccccc12>>CCOC(OCC)[C@H](C)NCc1cccc2ccccc12,,C1CCOC1,CCOC(C)=O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090318467A1,Cc1cc(-c2cccc(C(F)(F)F)c2)c(N(S(C)(=O)=O)S(C)(=O)=O)nc1C(=O)N1CCC(N2CCCC2)CC1>>Cc1cc(-c2cccc(C(F)(F)F)c2)c(NS(C)(=O)=O)nc1C(=O)N1CCC(N2CCCC2)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20030008361A1,CCOC(Cc1ccc(OCc2ccccc2)cc1)C(=O)O.CCOCCO>>CCOCCOC(=O)C(Cc1ccc(OCc2ccccc2)cc1)OCC,,CCOCCO,,,,test
US20080009530A1,CC(C)(O)CCO.CCOC(=O)/C=C/c1ccc(O)cc1Oc1ncc(C(F)(F)F)cc1Cl>>CCOC(=O)/C=C/c1ccc(OCCC(C)(C)O)cc1Oc1ncc(C(F)(F)F)cc1Cl,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20150080549A1,C[C@H](NC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](CC(=O)OCc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O>>C[C@H](NC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](CC(=O)O)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O,[Pd],CO,,[H][H],,test
US05420285,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NNc1ccc([N+](=O)[O-])cn1>>CC(C)(C)OC(=O)NNc1ccc([N+](=O)[O-])cn1,,CN(C)C=O,,CCN(CC)CC,,test
US20130217699A1,CC(=O)c1cc2c(Cl)cccc2s1.O=C(c1cc(Cl)cc(Cl)c1)C(F)(F)F>>O=C(CC(O)(c1cc(Cl)cc(Cl)c1)C(F)(F)F)c1cc2c(Cl)cccc2s1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20020137664A1,CC(C)(C)OC(=O)N1CCC(CN)(C2CCCCC2)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(CNS(C)(=O)=O)(C2CCCCC2)CC1,,ClCCl,,CCN(CC)CC,,test
US20070042974A1,C=CCC1CCOC1=O.N>>C=CCC(CCO)C(N)=O,,COCCOC,,,,test
US07071201B2,N#Cc1ccc2c(c1)N(C1CCN(CCc3ccc(F)cc3)CC1)CC2.O=S(=O)(O)O>>NC(=O)c1ccc2c(c1)N(C1CCN(CCc3ccc(F)cc3)CC1)CC2,,O=S(=O)(O)O,,CCOC(C)=O,[Na+].[OH-],test
US20110172245A1,COc1ccc(NC(=O)c2cccc(C3(C#N)CC3)c2)cc1O.O=[N+]([O-])c1ccc(F)cc1>>COc1ccc(NC(=O)c2cccc(C3(C#N)CC3)c2)cc1Oc1ccc([N+](=O)[O-])cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150239900A1,N=CN.Nc1c(C(=O)O)cc(Cl)c(Br)c1F>>O=c1[nH]cnc2c(F)c(Br)c(Cl)cc12,,CCO,,CC(=O)O,,test
US20080009541A1,CC1CC(=O)N(C)[C@@H]1C(=O)OC(C)(C)C>>CC1CC(=O)N(C)[C@@H]1C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070185079A1,CO.Fc1ccc2nc(Cl)cc(Cl)c2c1>>COc1cc(Cl)nc2ccc(F)cc12,,CO,,C[O-].[Na+],,test
US04551460,CC(C)c1ccc2nc3ccc(C(=O)O)cn3c(=O)c2c1.ClCCCCc1cccnc1>>CC(C)c1ccc2nc3ccc(C(=O)OCCCCc4cccnc4)cn3c(=O)c2c1,,CCOC(C)=O,CN(C)C=O,[I-].[K+],,test
US20090088459A1,CC(C)CNCc1ccc(-c2cccc(S(C)(=O)=O)c2)s1.N#Cc1ccccc1S(=O)(=O)Cl>>CC(C)CN(Cc1ccc(-c2cccc(S(C)(=O)=O)c2)s1)S(=O)(=O)c1ccccc1C#N,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04367238,COc1c(C=O)cccc1Oc1ccccc1Cl>>COc1c(CO)cccc1Oc1ccccc1Cl,,CO,,[BH4-].[Na+],,test
US20110288067A1,CO.C[C@@H](CC(=O)O)NC(=O)OC(C)(C)C>>COC(=O)C[C@H](C)NC(=O)OC(C)(C)C,,CO,Cc1ccccc1,C[Si](C)(C)C=[N+]=[N-],,test
US04933330,Nc1ccc(O)c(C(=O)O)c1.O=Cc1ccccc1>>O=C(O)c1cc(N=Cc2ccccc2)ccc1O,,Cc1ccccc1,,,,test
US20080009530A1,CCCCCS(N)(=O)=O.CCCCOc1cc(/C=C/C(=O)O)n(Cc2ccc(Cl)cc2Cl)n1>>CCCCCS(=O)(=O)NC(=O)/C=C/c1cc(OCCCC)nn1Cc1ccc(Cl)cc1Cl,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US04892875,CC(=O)CC(=O)OCCN1CCN(C(c2ccc(C)cc2)c2ccc(C)cc2)CC1.CCOC(=O)/C=C(/C)N.N#Cc1ccc(C=O)cc1>>CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCCN2CCN(C(c3ccc(C)cc3)c3ccc(C)cc3)CC2)C1c1ccc(C#N)cc1,,CC(C)O,,,,test
US04851030,NNC(=O)Cc1ccccc1S(N)(=O)=O.S=C=S>>NS(=O)(=O)c1ccccc1Cc1nnc(S)s1,,CCO,O,[K+].[OH-],,test
US05981533,CCOC(OCC)N(C)C.CN(C)c1ccc(Nc2n[nH]c(N)c2C#N)cc1>>CN(C)C=Nc1[nH]nc(Nc2ccc(N(C)C)cc2)c1C#N,,Cc1ccccc1,,,,test
US20140094459A1,C[C@H](Cn1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc21)NC(=O)C(C#N)=CC(C)(C)NC(=O)OC(C)(C)C.Cl>>C[C@H](Cn1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc21)NC(=O)C(C#N)=CC(C)(C)N.Cl,,C1COCCO1,CO,CCOCC,,test
US20080004316A1,C#Cc1nc(C)ccc1N.Fc1cc(F)cc(I)c1>>Cc1ccc(N)c(C#Cc2cc(F)cc(F)c2)n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCN(CC)CC,ClCCl,,,test
US20150018335A1,Clc1cccc(CN2CCNCC2)c1N1CCOCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OC(C(F)(F)F)C(F)(F)F>>O=C(OC(C(F)(F)F)C(F)(F)F)N1CCN(Cc2cccc(Cl)c2N2CCOCC2)CC1,,ClCCl,O,CCN(C(C)C)C(C)C,,test
US20100099657A2,CC1(C)COC(CS[C@H]2C(=O)N(c3ccc(F)cc3)[C@@H]2c2ccc(OCC(=O)OC(C)(C)C)cc2)(c2ccccc2)OC1>>O=C(O)COc1ccc([C@@H]2[C@@H](SCC(=O)c3ccccc3)C(=O)N2c2ccc(F)cc2)cc1,,O=CO,,,,test
US20140286903A1,CCO.C[C@@]1(OC(=O)c2ccccc2)[C@H](F)[C@@H](COC(=O)c2ccccc2)O[C@H]1n1cnc2c(Cl)nc(N)nc21>>CCOc1nc(N)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](F)[C@@]1(C)O,,CCO,CCO,C,C[O-].[Na+],test
US04371736,O=[N+]([O-])c1ccc(Cl)nc1.Oc1ccccc1Oc1ncc(Cl)cn1>>O=[N+]([O-])c1ccc(Oc2ccccc2Oc2ncc(Cl)cn2)nc1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04289763,CC(=O)OCC(=O)[C@H]1[C@H](C)C[C@H]2[C@@H]3C[C@H](Cl)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]12C>>C[C@@H]1C[C@H]2[C@@H]3C[C@H](Cl)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@H]1C(=O)CO,,CO,,[O-][Cl+3]([O-])([O-])O,,test
US20050192347A1,CC(CCCCN)(COC1CCCCO1)c1ccccc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(CCCCN=C=O)(COC1CCCCO1)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20070244169A1,CCCc1cc(Br)c(F)c(C(=O)O)c1.N>>CCCc1cc(Br)c(F)c(C(N)=O)c1,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US05279764,CCCCC[C@@H]1CC[C@@H](C(=O)O)CC1.CCCCCc1ccc(-c2ccc(O)c(F)c2F)cc1>>CCCCCc1ccc(-c2ccc(OC(=O)[C@@H]3CC[C@@H](CCCCC)CC3)c(F)c2F)cc1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US06235731B1,CN(CCCc1ccccc1)C(=O)C(F)(F)F>>CNCCCc1ccccc1,,CCO,O,[BH4-].[Na+],,test
US20160096827A1,Clc1ncnc(Cl)n1.Nc1cnn(C(F)F)c1>>FC(F)n1cc(Nc2ncnc(Cl)n2)cn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20140371199A1,CC(=O)OC(C)=O.CCC1(N)CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc(C#N)cc5)n4n3)cc2)CC1>>CCC1(NC(C)=O)CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc(C#N)cc5)n4n3)cc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20150266857A1,CC(C)(C)OC(=O)N1CC2(CN(CCc3nc4ccc(-c5c[nH]c6cc(F)ccc56)cc4o3)C2)C1>>Fc1ccc2c(-c3ccc4nc(CCN5CC6(CNC6)C5)oc4c3)c[nH]c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110054178A1,CCOC(=O)N1CCC(=O)CC1.Cc1ccc(Sc2ccccc2Br)cc1>>CCOC(=O)N1CCC(O)(c2ccccc2Sc2ccc(C)cc2)CC1,,C1CCOC1,,[Li]CCCC,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OCC3(O[Si](C)(C)C(C)(C)C)CC3)CC2)c2nc(C)nn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n([C@@H]2CC[C@@H](OCC3(O)CC3)CC2)c2nc(C)nn12,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US06245746B1,CC(C)(C)OC(=O)N[C@@H](CCc1ccccc1)C(=O)O.CN[C@@H](CCCNC(=O)OC(C)(C)C)C(=O)NCCCc1ccccc1>>CN(C(=O)[C@H](CCc1ccccc1)NC(=O)OC(C)(C)C)[C@@H](CCCNC(=O)OC(C)(C)C)C(=O)NCCCc1ccccc1,,C1CCOC1,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20050256170A1,CCOC(=O)COc1cccc(N)c1.O=C(O)c1ccc(-c2ccccc2)o1>>CCOC(=O)COc1cccc(NC(=O)c2ccc(-c3ccccc3)o2)c1,,CCOC(C)=O,,,,test
US20120302524A1,Nc1nnc(-c2ccco2)o1.O=C(Cl)c1ccc(I)cc1>>O=C(Nc1nnc(-c2ccco2)o1)c1ccc(I)cc1,,c1ccncc1,,,,test
US20120034270A1,CCCOC(=O)c1ccc(OCCC)c(OCCC)c1>>CCCOc1ccc(C(=O)O)cc1OCCC,,C1COCCO1,,O,[K+].[OH-],test
US05432169,CN.Cc1ccc(S(=O)(=O)OCCO[C@H]2CC[C@@]3(C)[C@H](CC[C@@H]4[C@@H]3CC[C@]3(C)[C@@H](c5ccoc5)CC[C@]43O)C2)cc1>>CNCCO[C@H]1CC[C@@]2(C)[C@H](CC[C@@H]3[C@@H]2CC[C@]2(C)[C@@H](c4ccoc4)CC[C@]32O)C1,,CO,,,,test
US04824951,CC(O)CN.O=[N+]([O-])c1cccnc1Cl>>CC(O)CNc1ncccc1[N+](=O)[O-],,CCO,,CCN(CC)CC,,test
US20040009979A1,NC(N)=O.Nc1ccc(I)cc1C(=O)O>>O=c1[nH]c(=O)c2cc(I)ccc2[nH]1,,CN1CCCC1=O,,O,,test
US20090298823A1,Clc1nc(NC2CCC2)c2c(Br)c[nH]c2n1.Nc1ccc2cn[nH]c2c1>>Brc1c[nH]c2nc(Nc3ccc4cn[nH]c4c3)nc(NC3CCC3)c12,,CCCCO,,C[Si](C)(C)Cl,,test
US20150232445A1,Cc1ccc2c(OC3CCC3)cc(F)c(F)c2n1>>C[C@H]1CCc2c(OC3CCC3)cc(F)c(F)c2N1,,CO,,[H][H],,test
US20140243286A1,CC(C)(C)OC(=O)NCCc1cccc(Br)c1.CCO[Si](C)(C)[Si](C)(C)OCC>>CC(C)(C)OC(=O)NCCc1cccc([Si](C)(C)O)c1,Cl[Pd]Cl,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US20130045964A1,CNC(=O)[C@@H](N)C(C)(C)C.O=C(O)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1>>CNC(=O)[C@@H](NC(=O)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1)C(C)(C)C,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120040954A1,Cc1cc(-c2nc3cc(F)cc(F)c3c(=O)[nH]2)cc(C)n1.OCCN1CCCC1>>Cc1cc(-c2nc3cc(F)cc(OCCN4CCCC4)c3c(=O)[nH]2)cc(C)n1,,CC(=O)O,CN(C)C=O,O,[H-].[Na+],test
US05837704,CCN1c2ncccc2C(=O)N(C)c2ccc(-c3cc[nH]c3)nc21.CI>>CCN1c2ncccc2C(=O)N(C)c2ccc(-c3ccn(C)c3)nc21,,CN(C)C=O,,O,[H-].[Na+],test
US05344843,C=CCO/N=C(\C(=O)OCC)c1ccc(OCCOc2ccc3ccccc3c2)s1>>C=CCO/N=C(\C(=O)O)c1ccc(OCCOc2ccc3ccccc3c2)s1,,C1CCOC1,CO,[Na+].[OH-],,test
US20160149138A1,CC(C)(C)OC(=O)N1c2ccsc2-c2sccc2S1(=O)=O>>O=S1(=O)Nc2ccsc2-c2sccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140256933A1,CC(C)(O)c1nc(Cl)ncc1F.N#Cc1ccc([C@]23CNC[C@H]2CSC(NC(=O)c2ccccc2)=N3)s1>>CC(C)(O)c1nc(N2C[C@H]3CSC(NC(=O)c4ccccc4)=N[C@@]3(c3ccc(C#N)s3)C2)ncc1F,,C1COCCO1,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20090186870A1,COC(=O)c1cc(O)ccc1Cl.N>>NC(=O)c1cc(O)ccc1Cl,,CO,,,,test
US08324232B2,CC(C)(C)O.NCc1ccccc1.O=C=NS(=O)(=O)Cl>>CC(C)(C)OC(=O)NS(=O)(=O)NCc1ccccc1,,ClCCl,,,,test
US20110212918A1,COC(=O)c1cc(N)cnc1SCc1ccccc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1cc(NC(=O)C(F)(F)F)cnc1SCc1ccccc1,,ClCCl,,,,test
US05109014,CCI.O=C(Nc1ccc(C(F)(F)F)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)N1>>CCN1C(c2ccc(Cl)cc2)C(c2ccccc2)CN1C(=O)Nc1ccc(C(F)(F)F)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05599903,N[C@@H](CC(=O)O)C(=O)O.O=C(OCC1c2ccccc2-c2ccccc21)ON1C(=O)CCC1=O>>O=C(O)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O,,C1COCCO1,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US03960863,Cc1nc2ccc(Cl)cn2c(=O)c1CCCl.Clc1cccc(N2CCNCC2)c1>>Cc1nc2ccc(Cl)cn2c(=O)c1CCN1CCN(c2cccc(Cl)c2)CC1,,Cc1ccccc1,,,,test
US06472414B1,CCCCOP(=O)(C/C=C/CC1(C(=O)NCCC)c2cc(F)ccc2-c2ccc(F)cc21)OCCCC>>CCCCOP(=O)(CCCCC1(C(=O)NCCC)c2cc(F)ccc2-c2ccc(F)cc21)OCCCC,[Pd],,,,,test
US20080280923A1,CCOC(=O)c1cc2cc(Cl)ccc2n1Cc1cccc(C)c1>>Cc1cccc(Cn2c(C(=O)O)cc3cc(Cl)ccc32)c1,,CCO,,[Na+].[OH-],,test
US20150361053A1,COC(=O)c1ccc(C(F)(F)F)cc1N=C=S.NC1Cc2ccccc2C1>>O=c1c2ccc(C(F)(F)F)cc2[nH]c(=S)n1C1Cc2ccccc2C1,,CN(C)C=O,,O,,test
US20070155805A1,CCCCC(CCBr)c1sc2cc(C(F)(F)F)ccc2c1C.CCOC(=O)Cc1sc(S)nc1C>>CCCCC(CCSc1nc(C)c(CC(=O)OCC)s1)c1sc2cc(C(F)(F)F)ccc2c1C,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050197350A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](N)CC1.O=C(Cl)OCc1ccccc1>>N[C@@H]1CC[C@H](NC(=O)OCc2ccccc2)CC1,,CCOC(C)=O,ClC(Cl)Cl,CCN(CC)CC,Cl,test
US20090275537A1,COC(=O)CC[C@@H](CO[Si](C)(C)C(C)(C)C)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H](CCCO)CO[Si](C)(C)C(C)(C)C,,C1CCOC1,CO,[BH4-].[Li+],,test
US20090099250A1,C=CCC1=C(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)CCCc2cc(OC)ccc21.COc1ccc(B(O)O)cc1>>C=CCC1=C(c2ccc(OC)cc2)CCCc2cc(OC)ccc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20130345438A1,C[N+](=O)[O-].O=C1Nc2ccc(Br)cc2C1=O>>O=C1Nc2ccc(Br)cc2C1(O)C[N+](=O)[O-],,O,,,,test
US20090036492A1,CCI.COc1cc(O)c2c(c1C(=O)OCc1ccccc1)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>CCOc1cc(OC)c(C(=O)OCc2ccccc2)c2c1[C@]1(C)C(=O)C(C(C)=O)=C(O)C=C1O2,,CN(C)C=O,,Cl,[H-].[Na+],test
US05420275,Cc1cc(C)nc(SC(=O)OC(C)(C)C)n1.O=C(O)CNc1ccc(O)cc1>>CC(C)(C)OC(=O)N(CC(=O)O)c1ccc(O)cc1,,C1COCCO1,O,CCN(CC)CC,,test
US20160244417A1,CC(C)(C)OC(=O)[C@@H]1CCC(F)(F)C[C@H]1C(=O)Cl.C[Si](C)(C)C=[N+]=[N-].Cl>>CC(C)(C)OC(=O)[C@@H]1CCC(F)(F)C[C@H]1C(=O)CCl,,C1CCOC1,,CC#N,,test
US20110028390A1,CCOC(=O)c1cc(OC(C)=O)c2c(cnn2C2CCCCO2)c1>>CCOC(=O)c1cc(O)c2c(cnn2C2CCCCO2)c1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20100261719A1,CC1CNCC(C)O1.O=Cc1cc(I)c(F)c(F)c1F>>C[C@H]1CN(c2c(C=O)cc(I)c(F)c2F)C[C@@H](C)O1,,CC#N,,CCN(CC)CC,,test
US20090298807A1,Cc1nc(C(=O)N2CCOC3(CCN(C(=O)OC(C)(C)C)CC3)CC2)cs1.O=C(O)C(F)(F)F>>Cc1nc(C(=O)N2CCOC3(CCNCC3)CC2)cs1.O=C(O)C(F)(F)F,,ClCCl,,Cc1ccccc1,,test
US20160107997A1,COc1ccc(CN(CCN(Cc2ccccc2C(F)(F)F)C(=O)CNc2cccc3c2CCN(CC2CC2)C3)CC(F)(F)F)cc1>>O=C(CNc1cccc2c1CCN(CC1CC1)C2)N(CCNCC(F)(F)F)Cc1ccccc1C(F)(F)F,[Pd],CO,,CC(=O)O,,test
US20040072816A1,CCOc1ccc(S(=O)(=O)N(c2ccc(C)cc2)C(C)C(=O)OC)cc1.NN>>CCOc1ccc(S(=O)(=O)N(c2ccc(C)cc2)C(C)C(=O)NN)cc1,,CO,,O,,test
US20150005282A1,CCC(=O)Cl.COC(=O)C[C@@H]1COc2cc(OCc3cccc(-c4c(C)cc(OC5CNC5)cc4C)c3)ccc21>>CCC(=O)N1CC(Oc2cc(C)c(-c3cccc(COc4ccc5c(c4)OC[C@H]5CC(=O)OC)c3)c(C)c2)C1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20090197863A1,NC(=O)c1cccc2nc(C3CN(C(=O)OCc4ccccc4)C3)oc12>>NC(=O)c1cccc2nc(C3CNC3)oc12,[Pd],CO,,,,test
US20150152118A1,CCOC(=O)C(C)(C)N1CCN(c2ccc(F)cc2)CC1>>CC(C)(CO)N1CCN(c2ccc(F)cc2)CC1,,CCOC(C)=O,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20120208827A1,CC(C)(C)OC(=O)N1CC[C@@H](CN)C1.O=[N+]([O-])c1cc(Br)c(F)cc1F>>CC(C)(C)OC(=O)N1CC[C@@H](CNc2cc(F)c(Br)cc2[N+](=O)[O-])C1,,CCO,,,,test
US05981420,C1CCCCC1.N#Cc1ccccc1.O=C1c2ccccc2C(=O)N1O>>O=C1CCCCC1.OC1CCCCC1,,C1CCCCC1,,,,test
US20080255083A1,O=C(Cn1ccc(OCc2ccc(F)cc2)cc1=O)c1ccc(CO)cc1.O=S(Cl)Cl>>O=C(Cn1ccc(OCc2ccc(F)cc2)cc1=O)c1ccc(CCl)cc1,,ClCCl,O,c1ccncc1,,test
US20070129347A1,CN(C)C1(c2cccc(F)c2)CCC(CC(=O)NCCCc2ccccc2)CC1.C[Si](C)(C)Cl>>CN(C)C1(c2cccc(F)c2)CCC(CC(=O)NCCCc2ccccc2)CC1.Cl,,CCC(C)=O,,CCOCC,,test
US20150080549A1,CNC(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC(C)(C)C>>CNC(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100029643A1,CCN.CCOC(OCC)OCC.N#CC(N)C(N)=O>>CCn1cnc(C(N)=O)c1N,,CC#N,,,,test
US05741437,COS(=O)(=O)OC.N#CCN1CCOCC1>>CC#N.C[NH+]1CCOCC1,,CCOC(C)=O,,,,test
US20020045615A1,CC(=O)Cl.COc1ccc(N2CCNCC2)c2sc(NC(=O)c3ccc(C)s3)nc12>>COc1ccc(N2CCN(C(C)=O)CC2)c2sc(NC(=O)c3ccc(C)s3)nc12,,CN(C)C=O,,c1ccncc1,,test
US20110021537A1,CC(C)(C)OC(=O)CC[C@H](NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NCCF)n(-c2ccccc2)n1)C(=O)O.CCOC(=O)N1CCNC[C@H]1C>>CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)O)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)NCCF)n(-c3ccccc3)n2)C[C@H]1C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05451700,CC(=O)Oc1ccccc1.COc1cc(C(=O)N(C(C)C)C(C)C)ccc1OCCCCCOc1ccc(C=NN)cc1>>COc1cc(C(=O)N(C(C)C)C(C)C)ccc1OCCCCCOc1ccc(CN=NC(C)=O)cc1,,ClCCl,,,,test
US04501893,Cc1ccc(C(O)(CCN2CCCC2)c2cccc(C=O)n2)cc1.O=C(O)CC(=O)O>>COC(=O)/C=C/c1cccc(C(O)(CCN2CCCC2)c2ccc(C)cc2)n1,,c1ccncc1,,C1CCNCC1,,test
US20110213156A1,COC(=O)c1ccc(NC(=O)c2cc(C(C)C)c(C(C)C)s2)cc1F>>CC(C)c1cc(C(=O)Nc2ccc(C(=O)O)c(F)c2)sc1C(C)C,,[Na+],[OH-],,,test
US04040813,CC(=O)OC(C)=O.CCCCCCCCCCCC[N+](C)(C)C1CCCCC1O.[Br-]>>CCCCCCCCCCCC[N+](C)(C)C1CCCCC1OC(C)=O.[Br-],,O,,c1ccncc1,,test
US20140336388A1,CCN=C=NCCCN(C)C.Nc1ccc(N2CCC(c3n[nH]c(=O)o3)CC2)cc1.O=C(O)c1ccc([N+](=O)[O-])o1.Oc1cccc2[nH]nnc12>>N#N.NC(=O)c1oc([N+](=O)[O-])cc1-c1ccc(N2CCC(c3n[nH]c(=O)o3)CC2)cc1,,CN(C)C=O,,,,test
US06046214,CC(=O)OC(C)=O.CN1CC=CC(CO)C1>>CC(=O)OC1C=CCN(C)C1,,CCN(CC)CC,,,,test
US20110301181A1,Cn1nc(C(O)C2CC2)c(C(F)(F)F)c1C(=O)O.Nc1ccc(Cl)c(C(=O)NC2CC2)c1>>Cn1nc(C(O)C2CC2)c(C(F)(F)F)c1C(=O)Nc1ccc(Cl)c(C(=O)NC2CC2)c1,,C1CCOC1,,COc1nc(OC)nc([N+]2(C)CCOCC2)n1.[Cl-],,test
US20090005344A1,COc1ccc(C=O)cc1F.Nc1ccccc1N>>COc1ccc(-c2nc3ccccc3[nH]2)cc1F,,O=[N+]([O-])c1ccccc1,,,,test
US20100240658A1,COC(=O)c1cc(OC)c([N+](=O)[O-])cc1F>>COC(=O)c1cc(OC)c(N)cc1F,[Pd],CO,,,,test
US20040006114A1,Nc1cccc(Br)c1.O=Cc1cccnc1>>Brc1cccc(NCc2cccnc2)c1,,CO,,[BH4-].[Na+],,test
US20100210639A1,CC(C)(C)OC(=O)NCC1CN(c2ncnc3[nH]c4ccccc4c23)CCO1>>NCC1CN(c2ncnc3[nH]c4ccccc4c23)CCO1,,CO,,C1COCCO1,Cl,test
US20130331375A1,C[Si](C)(C)CCOCn1ccc2c(=O)[nH]c(-c3ccc(C(F)(F)F)cc3)nc21>>O=c1[nH]c(-c2ccc(C(F)(F)F)cc2)nc2c1ccn2CO,,ClCCl,,O=C(O)C(F)(F)F,,test
US04288436,CCOC(=O)Cc1csc(NC(=O)OC(C)(C)CC)n1.O=[Se]=O>>CCOC(=O)C(=O)c1csc(NC(=O)OC(C)(C)CC)n1,,C1COCCO1,O,,,test
US05438052,COC(=O)CC(=O)C(=O)OC.Cc1nc(N)n[nH]1>>COC(=O)c1cc(O)n2nc(C)nc2n1,,CC(=O)O,,,,test
US20100324307A1,CC(C)C[C@H](CC(=O)O)CC(=O)N[C@@H](C)c1ccccc1.CC(C)C[C@H](CC(N)=O)CC(=O)N[C@@H](C)c1ccccc1>>CC(C)C[C@H](CC(N)=O)CC(=O)O.C[C@H]([NH-])c1ccccc1,,ClCCl,,CCN(CC)CC,CCOC(=O)Cl,test
US20040002526A1,CN(C)c1ccc(C=CC=O)cc1.O=C(O)c1ccc(N2C(=O)CSC2=S)cc1>>CN(C)c1ccc(C=CC=C2SC(=S)N(c3ccc(C(=O)O)cc3)C2=O)cc1,,CCO,O,C1CCNCC1,Cl,test
US20050020587A1,CC(C)(C)OC(=O)NN1CCC(N)CC1.O=C(O)c1cc(F)cnc1Cl>>CC(C)(C)OC(=O)N1CCC(NC(=O)c2cc(F)cnc2Cl)CC1,,CN(C)C=O,,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US20070149533A1,ClCCN1CCCC1.O=[N+]([O-])c1cc(O)cc(C(F)(F)F)c1>>O=[N+]([O-])c1cc(OCCN2CCCC2)cc(C(F)(F)F)c1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20070248567A1,CN(C)C=O.CN(C)c1ccncc1.NCCCC[C@H](N)C(=O)O.O=C1CCCC(=O)O1>>NC(=O)CCCC(N)=O.NCCCC[C@H](N)C(=O)O,CN(C)c1ccncc1,,,,,test
US04067973,Cl.Clc1ccccc1N=Nc1ncc[nH]1>>Cl.Clc1ccccc1N=Nc1ncc[nH]1,,CCO,,,,test
US06136831,CC(=O)N(C)C.Cc1ccc2ncsc2c1>>CC(=O)c1nc2ccc(C)cc2s1,,C1CCOC1,,O,[Li]CCCC,test
US20140031360A1,CC(C)(C)OC(=O)N1CCC[C@@H](O)C1.Clc1cncc(-c2nn(C3CCCCO3)c3ccc(Br)cc23)n1>>CC(C)(C)OC(=O)N1CCC[C@@H](Oc2cncc(-c3nn(C4CCCCO4)c4ccc(Br)cc34)n2)C1,,CN(C)C=O,,[H-].[Na+],,test
US20050059650A1,CCCCCO.CS(=O)(=O)c1ccc(-n2ncc3c(OC4CCNCC4)ncnc32)cc1.O=C(n1ccnc1)n1ccnc1>>CCCCCOC(=O)N1CCC(Oc2ncnc3c2cnn3-c2ccc(S(C)(=O)=O)cc2)CC1,,CS(C)=O,,CCN(CC)CC,,test
US20060135773A1,CCOP(=O)(OCC)C(F)(F)c1ccc(CNCc2ccc(C(F)(F)P(=O)(OCC)OCC)cc2)cc1.O=S(=O)(Cl)c1ccccc1Cl>>CCOP(=O)(OCC)C(F)(F)c1ccc(CN(Cc2ccc(C(F)(F)P(=O)(OCC)OCC)cc2)S(=O)(=O)c2ccccc2Cl)cc1,CN(C)c1ccncc1,ClCCl,,Cl,,test
US20030100608A1,CCOC(=O)[C@@H]1C[C@H]1C1CCCCC1>>O=C(O)[C@@H]1C[C@H]1C1CCCCC1,,CO,,[Na+].[OH-],,test
US20130252941A1,Cc1nc(N)cc(Cl)n1.NCCO>>Cc1nc(N)cc(NCCO)n1,,CCOC(C)=O,,CO,,test
US20040077669A1,CC#CCO.Fc1cccc(Cl)c1Cc1cc(Cl)ncn1>>CC#CCOc1cc(Cc2c(F)cccc2Cl)ncn1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US05457192,O=C(O)c1ccc(Cl)cc1.O[C@H]1C=C[C@H]2CO[C@@H]1O2>>O=C(O[C@@H]1C=C[C@H]2CO[C@@H]1O2)c1ccc(Cl)cc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130059849A1,Cc1cc(C)c(CNC(=O)c2cc(Cl)nc3c2cnn3C(C)C)c(=O)[nH]1>>Cc1cc(C)c(CNC(=O)c2ccnc3c2cnn3C(C)C)c(=O)[nH]1,[Pd],C1CCOC1,,CCO,,test
US05773530,CCOC(=O)CN(C)C(=O)CC1=C(n2nc(-c3c(-c4ccccc4)nn4ccccc34)ccc2=O)CCCC1>>CN(CC(=O)O)C(=O)CC1=C(n2nc(-c3c(-c4ccccc4)nn4ccccc34)ccc2=O)CCCC1,,C1COCCO1,O,CCOC(C)=O,[Na+].[OH-],test
US20090203690A1,C1CCOC1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN(C)c1ccncc1.Nc1n[nH]c2ccc(Br)cc12>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nn(C(=O)OC(C)(C)C)c2ccc(Br)cc12,CN(C)c1ccncc1,C1CCOC1,,,,test
US04207254,Cc1cc(N)c(S(=O)(=O)O)cc1Cl>>Cc1ccc(S(=O)(=O)O)cc1,,Cc1ccccc1,,O=S(=O)(O)O,,test
US20040127574A1,O=C(O)C(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccc(F)cc1F.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>O=C1NC(Cc2ccc(C(F)(F)F)cc2)C(c2ccc(F)cc2F)O1,,C1CCOC1,,CCN(CC)CC,O,test
US20120323000A1,C=CCCC[C@H](C)[C@H](O)[C@@H](C)C(=O)C(C)(C)[C@H](CC(=O)O[C@@H](CC=C)/C(C)=C/c1csc(C)n1)O[Si](C)(C)C(C)(C)C.CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F>>C=CCCC[C@H](C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)C(=O)C(C)(C)[C@H](CC(=O)O[C@@H](CC=C)/C(C)=C/c1csc(C)n1)O[Si](C)(C)C(C)(C)C,,ClCCl,,Cc1cccc(C)n1,,test
US20040192728A1,CC(=O)Cl.O=C(Nc1cnc2ccccc2c1)c1ccc2c(c1)CCN2>>CC(=O)N1CCc2cc(C(=O)Nc3cnc4ccccc4c3)ccc21,,ClCCCl,,CCN(C(C)C)C(C)C,,test
US20090099163A1,CC(C)(C)OC(=O)N[C@@H](CC1CCCCC1)C(=O)Nc1nccs1>>N[C@@H](CC1CCCCC1)C(=O)Nc1nccs1,,O=C(O)C(F)(F)F,,,,test
US20060069154A1,CC(C)(C)[Si](C)(C)OCCN(CCO[Si](C)(C)C(C)(C)C)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)[Si](C)(C)OCCN(CCO[Si](C)(C)C(C)(C)C)c1ccc(N)cc1,[Pd],C1CCOC1,,,,test
US20100160385A1,CCC(=O)c1c(F)cc(F)cc1F.COc1cc(N)c(Cl)c(OC)c1>>CCC(=Nc1cc(OC)cc(OC)c1Cl)c1c(F)cc(F)cc1F,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05393875,COC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)S(=O)(=O)CC(Cc1ccccc1)C(=O)O.O=C(Cl)OCc1ccccc1>>COC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)(C)S(=O)(=O)CC(Cc1ccccc1)C(=O)O,,C1COCCO1,,Cl,,test
US04927822,CC(=O)SCCC(=O)Cl.O=C(OCc1ccccc1)C1NN=C(c2ccc(C(F)(F)F)cc2)S1>>CC(=O)SCCC(=O)N1N=C(c2ccc(C(F)(F)F)cc2)SC1C(=O)OCc1ccccc1,,Cc1ccccc1,,CCOCC,,test
US20060079523A1,FC(F)(F)c1ccc(S)nc1.O=Cc1ccc(F)cc1>>O=Cc1ccc(Sc2ccc(C(F)(F)F)cn2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160168090A1,CC(C)(C)OC(=O)N1CCCC1CO.O=C(NCC1(O)CCCC(F)(F)C1)c1c[nH]c2cccc(Cl)c12>>O=C(NCC1(O)CCCC(F)(F)C1)c1cn(CC2CCCN2)c2cccc(Cl)c12,,Cc1ccccc1,,CCCCP(=CC#N)(CCCC)CCCC,,test
US20110190257A1,CC(C)(C)OC(=O)c1ccc2c(cnn2C(=O)OC(C)(C)C)c1Nc1ccc([Si](C)(C)C)cc1F.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)c1ccc2c(cnn2C(=O)OC(C)(C)C)c1Nc1ccc(Br)cc1F,,ClCCl,,,,test
US20080269244A1,CS(=O)(=O)O.Cc1ccc(-n2nc(C(C)(CF)CF)cc2NC(=O)Nc2ccnc(OC3CCN(C(=O)c4c(F)cccc4F)CC3)c2)cc1>>CS(=O)(=O)O.Cc1ccc(-n2nc(C(C)(CF)CF)cc2NC(=O)Nc2ccnc(OC3CCN(C(=O)c4c(F)cccc4F)CC3)c2)cc1,,CO,ClCCl,,,test
US04345084,C#CCO.CCCCCCCC/C=C\CCl>>CCCCCCCC/C=C\CC#CCO,Cl[Cu],,,,,test
US20080139631A1,Cc1cc2c(C(F)(F)F)cccc2n1S(=O)(=O)c1ccccc1>>Cc1cc2c(C(F)(F)F)cccc2[nH]1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US06316482B1,C=O.CO.COc1c(-c2cccc3[nH]c(C)nc23)ccc(C(=O)N(C)c2ccc(C)cc2OCCCCN)c1N=C=O>>COc1c(-c2cccc3[nH]c(C)nc23)ccc(C(=O)N(C)c2ccc(C)cc2OCCCCN(C)C)c1N=C=O,,CO,ClC(Cl)Cl,[BH3-]C#N.[Na+],,test
US20110245251A1,NNCc1ccccc1.O=C1C=C(c2ccccc2)C(=O)O1>>O=c1cc(-c2ccccc2)c(O)nn1Cc1ccccc1,,CC(=O)O,,,,test
US20130237525A1,CCOC(OCC)OCC.COc1ccc(N)c(O)c1C1CCCC(=O)N1Cc1ccc2ccccc2n1>>COc1ccc2ncoc2c1C1CCCC(=O)N1Cc1ccc2ccccc2n1,,CCOC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05721234,BrBr.CC(=O)Nc1ccc2c(c1)CC(NC(C)=O)C2>>CC(=O)Nc1cc2c(cc1Br)CC(NC(C)=O)C2,,CC(=O)O,,,,test
US05614532,C=CCBr.O=c1[nH]c2cc(Cl)ccc2c(O)c1-c1ccccc1>>C=CCOc1c(-c2ccccc2)c(=O)[nH]c2cc(Cl)ccc12,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US20130053365A1,COC(=O)c1cc(F)cc(NC(=O)OC(C)(C)C)c1C(=O)/C(=C/c1ccc(F)cc1)c1ncnn1C.C[N+](=O)[O-]>>COC(=O)c1cc(F)cc(NC(=O)OC(C)(C)C)c1C(=O)C(c1ncnn1C)C(C[N+](=O)[O-])c1ccc(F)cc1,,C1CCOC1,,C1CCC2=NCCCN2CC1,O,test
US20140315888A1,C1CC2CNCCN2C1.Clc1nc2cc(I)cnc2nc1Cl>>Clc1nc2cc(I)cnc2nc1N1CCN2CCCC2C1,,ClCCl,,,,test
US20110039829A1,CC(C)(C)OC(=O)CC[C@H](NC(=O)OC(C)(C)C)C(=O)O.Cc1cc(C)cc(N2CCNCC2)c1>>Cc1cc(C)cc(N2CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)CC2)c1,,CN(C)C=O,ClCCCl,CCN(C(C)C)C(C)C,On1nnc2ccccc21,test
US20060084663A1,COC(=O)CCc1ccc(O)cc1C.Cc1ccc(S(=O)(=O)OCCc2nc(-c3ccc(Cl)nc3)oc2C)cc1>>COC(=O)CCc1ccc(OCCc2nc(-c3ccc(Cl)nc3)oc2C)cc1C,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05374732,FC(F)(F)c1cnc(Cl)c(Cl)c1.O=S([O-])O.[Na+]>>O=S(=O)([O-])c1ncc(C(F)(F)F)cc1Cl.[Na+],,O,,CCO,,test
US20130310362A1,Cc1nc(N)c(-c2ccccc2)c(-c2ccc(C=O)cc2)n1.O=CCCl>>O=Cc1ccc(-c2ncn3ccnc3c2-c2ccccc2)cc1,,CCO,,,,test
US20030004341A1,CCOC(=O)CBr.c1ccc2c(c1)Nc1ccccc1O2>>CCOC(=O)CN1c2ccccc2Oc2ccccc21,,CN(C)C=O,,O,[H-].[Na+],test
US06013658,CCOC(=O)c1noc([C@@H](Cc2ccc3ccccc3c2)N(C)C(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)C2CCN(C(=O)OC(C)(C)C)CC2)n1>>CN(C(=O)C(Cc1ccc2ccccc2c1)NC(=O)C1CCN(C(=O)OC(C)(C)C)CC1)C(Cc1ccc2ccccc2c1)c1nc(C(=O)O)no1,,C1COCCO1,O,[Li+].[OH-],,test
US20100063047A1,Brc1nccc2sccc12.NCCc1ccc(Cl)cc1>>Clc1ccc(CCNc2nccc3sccc23)cc1,,CO,,ClCCl,,test
US04289776,CC(=O)CCCCn1cnc2c1c(=O)[nH]c(=O)n2C.CCCBr>>CCCn1c(=O)c2c(ncn2CCCCC(C)=O)n(C)c1=O,,CO,O,O=S(=O)(O)O,[Na+].[OH-],test
US05736559,CCOC(=O)C1CCCNC1.N#Cc1ccc(-c2ccc(OCC(=O)O)cc2)cc1>>CCOC(=O)C1CCCN(C(=O)COc2ccc(-c3ccc(C#N)cc3)cc2)C1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20120184508A1,Clc1ncc(Br)c(Cl)n1.O=Cc1cccc(Br)n1>>OC(c1cccc(Br)n1)c1cnc(Cl)nc1Cl,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20130217680A1,CCOC(=O)C(C(=O)OCC)c1ccc([N+](=O)[O-])cc1Br>>O=C(O)Cc1ccc([N+](=O)[O-])cc1Br,,CO,O,[K+].[OH-],,test
US20090029955A1,C1CSCCN1.CC1(C)CCc2c(N3CCOCC3)nc3sc4c(=O)[nH]cnc4c3c2C1>>CC1(C)CCc2c(N3CCSCC3)nc(S)c(C#N)c2C1,,CCO,,,,test
US20060172983A1,COC(=O)COc1ccc(N)cc1.O=C(O)COCc1ccccc1>>COC(=O)COc1ccc(NC(=O)COCc2ccccc2)cc1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20130045942A1,Cl.ON=Cc1ccccc1>>Cl.NCc1ccccc1,[Pd],CCO,,,,test
US20150239900A1,CC(C)(C)OC(=O)N1CCN(c2ncnc3cc(Br)c(Cl)cc23)CC1.CCCC[Sn](CCCC)(CCCC)[Sn](CCCC)(CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)c1cc2ncnc(N3CCN(C(=O)OC(C)(C)C)CC3)c2cc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US06194435B1,Cc1ccc(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)OC(C)(C)C)C(=O)O)cc1.c1cscn1>>Cc1ccc(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)O)cc1.c1cscn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050054674A1,Cc1cc(C(=O)CCc2nc(-c3ccc(Cl)cc3Cl)oc2C(C)C)ccc1O>>Cc1cc(C(O)CCc2nc(-c3ccc(Cl)cc3Cl)oc2C(C)C)ccc1O,,C1CCOC1,,[H-].[Na+],,test
US20140031355A1,CC(=O)Cl.CC(O)C#Cc1ccccc1C=O>>CC(=O)OC(C)C#Cc1ccccc1C=O,,ClCCl,,CCN(CC)CC,,test
US05643878,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H]1C[C@@H](Cc2ccc(OCc3ccccc3)cc2)C(=O)O1.O>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O,,COCCOC,O,[Li+].[OH-],,test
US20100311729A1,CCOC(=O)C(COC(C)=O)(Oc1ccc(Br)cc1)C(=O)OCC>>OCC(CO)(CO)Oc1ccc(Br)cc1,,C1CCOC1,,[BH4-].[Li+],,test
US20130203802A1,BrP(Br)Br.Cc1ccnc(CO)c1F>>Cc1ccnc(CBr)c1F,,C1CCOC1,,,,test
US20090170791A1,CCOC(=O)C(=CN(C)C)C(=O)c1cc(I)ccc1F.COCCN>>CCOC(=O)c1cn(CCOC)c2ccc(I)cc2c1=O,,CCO,,,,test
US20060160877A1,BrCc1ccccc1.COc1ccccc1-c1cccc2cc(C(=O)N[C@H]3CN4CCC3CC4)oc12>>COc1ccccc1-c1cccc2cc(C(=O)N[C@H]3C[N+]4(Cc5ccccc5)CCC3CC4)oc12.[Br-],,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US06004897,Cc1ccc(S(=O)(=O)O)cc1.Cc1ccccc1>>CC1=Cc2ccccc2C1C,,Cc1ccccc1,,,,test
US20100256188A1,CCOC(=O)c1cc(N)c(N)cc1OCC(F)F.O=C(NCc1ccc(Cl)c(N=C=S)c1)C1(C(F)(F)F)CC1>>CCOC(=O)c1cc2nc(Nc3cc(CNC(=O)C4(C(F)(F)F)CC4)ccc3Cl)[nH]c2cc1OCC(F)F,,C1CCOC1,,CC(C)N=C=NC(C)C,,test
US20080090889A1,CC(C)=CCn1c(SCCCNC(=O)OC(C)(C)C)nc2ccc([N+](=O)[O-])cc21>>CC(C)=CCn1c(SCCCNC(=O)OC(C)(C)C)nc2ccc(N)cc21,[Fe],CCO,O,[Cl-].[NH4+],,test
US20100286145A1,NO.O=Cc1cccc2cc[nH]c12>>O/N=C\c1cccc2cc[nH]c12,,CCO,O,[Na+].[OH-],,test
US20040122002A1,COC(=O)c1c(-c2ccc(Cl)cc2)c(-c2ccccc2)c2n1CCC2.N.O=S(=O)(O)Cl>>COC(=O)c1c(-c2ccc(Cl)cc2)c(-c2ccc(S(N)(=O)=O)cc2)c2n1CCC2,,CC(Cl)Cl,,O,,test
US20090312338A1,CNN.O=Cc1cnc2[nH]ccc2c1Cl>>Cn1ncc2cnc3[nH]ccc3c21,,CCCCO,,Cl,O,test
US20140142083A1,CCOC(C)=O.CI.Cc1c(C(=O)O)cc(O)cc1[N+](=O)[O-]>>COC(=O)c1cc(OC)cc([N+](=O)[O-])c1C,,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US04929755,C1=CNCC1.C1CCOC1.CC1CCC(C(C)C)C(OCC(=O)Cl)C1.CO.c1ccncc1>>O=C(O)[C@@H]1CCCN1.O=C(O)[C@H]1CCCN1,,C1CCOC1,,,,test
US20020086891A1,C#CC1(OC(C)=O)CCCCC1.CCNC(C)O>>C#CC1(N(CC)CCO)CCCCC1,Cl[Cu],,,C1CCOC1,,test
US20030181494A1,Cc1ccc(C=C(C(=O)O)c2ccc(O)cc2)cc1.O=Cc1ccc(F)cc1>>Cc1ccc(C=C(C(=O)O)c2ccc(Oc3ccc(C=O)cc3)cc2)cc1,,CC(=O)N(C)C,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20120258949A1,COC(=O)/C=C/c1ccc2c(c1)C(=O)CC1(CCCN(C(=O)OC(C)(C)C)C1)O2.O=Cc1ccc(F)cc1>>COC(=O)/C=C/c1ccc2c(c1)C(=O)CC1(CCCN(Cc3ccc(F)cc3)C1)O2,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20060264486A1,BrCCCBr.COC(=O)Cn1ccc2cc(O)ccc21>>COC(=O)Cn1ccc2cc(OCCCBr)ccc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04363917,CN=C(O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1C(=O)O.Sc1ccc(Cl)c(Cl)c1>>CN=C(O)c1cc([N+](=O)[O-])cc(Sc2ccc(Cl)c(Cl)c2)c1C(=O)O,,C1CCOC1,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20140088101A1,CN(CCN)S(C)(=O)=O.COC(=O)c1nc(-c2cccnc2)c2c(cc(-c3ccccc3)c(=O)n2Cc2ccccc2)c1O>>CN(CCNC(=O)c1nc(-c2cccnc2)c2c(cc(-c3ccccc3)c(=O)n2Cc2ccccc2)c1O)S(C)(=O)=O,,CCO,,Cl,C[O-].[Na+],test
US20150307916A1,CC(C)(C)OC(=O)CCCNC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)CCCN,[Pd],CO,,,,test
US06100283,Nc1cccc(C(=O)O)c1N.O=CO>>O=C(O)c1cccc2ocnc12,,Cl,,,,test
US20060148858A1,CC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO.CCOC(=O)Cc1cn(C2CCCCC2)nc1O>>CC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCOc1nn(C2CCCCC2)cc1CC(=O)O,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20110009395A1,CS(=O)(=O)OCC1COCC=C1c1cccc(Br)c1.NC(N)=S>>CS(=O)(=O)O.N=C(N)SCC1COCC=C1c1cccc(Br)c1,,CC(C)O,,CC#N,,test
US20130252937A1,O=C1CCc2c(C3=CCOCC3)ccc(F)c21>>O=C1CCc2c(C3CCOCC3)ccc(F)c21,[Pd],C1CCOC1,,,,test
US04493844,CC1(C)[C@H](C=C(Cl)C(F)(F)F)[C@@H]1C(=O)Cl.NCc1cccc2c1CCCc1ccccc1-2>>CC1(C)[C@H](C=C(Cl)C(F)(F)F)[C@@H]1C(=O)NCc1cccc2c1CCCc1ccccc1-2,,c1ccccc1,,O,c1ccncc1,test
US20060173199A1,CC1(C)OC[C@@H]2OC[C@@H](O)[C@@H](O)[C@H]2O1>>OC[C@@H]1OC[C@@H](O)[C@@H](O)[C@H]1O,,CO,,Cl,,test
US20130046004A1,BrBr.COc1cc(C(=O)O)nn1-c1ccccc1F>>COc1c(Br)c(C(=O)O)nn1-c1ccccc1F,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20080039458A1,BrC1NCCc2ccccc21.C1CCOC1.OBO>>CC1NCCc2c1ccc1c2OCCO1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O,O=C([O-])[O-].[K+].[K+],test
US20050026916A1,CI.S=C1N[C@@H](c2cccc(Cl)c2)[C@@H](c2cccc(Cl)c2)N1>>CSC1=N[C@@H](c2cccc(Cl)c2)[C@@H](c2cccc(Cl)c2)N1.I,,CCO,,,,test
US06492355B1,CC(C)(C)OC(=O)N1CCC(C(C)(O)c2ccc(Cl)c(C(=O)NCC34CC5CC(CC(C5)C3)C4)c2)CC1.Cl>>CC(O)(c1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1)C1CCNCC1.Cl,,C1COCCO1,CO,,,test
US20140018313A1,CC(C)(C)OC(=O)N1[C@@H]2CC[C@@H](C2)[C@H]1c1nc2ccc3cc(Br)ccc3c2[nH]1.COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1)C(C)C>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc(-c3ccc4c(ccc5nc([C@@H]6[C@H]7CC[C@H](C7)N6C(=O)OC(C)(C)C)[nH]c54)c3)cc2)[nH]1)C(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20130029971A1,CCOC(=O)CC1CCN(c2nc(S(C)(=O)=O)ccc2N)CC1.O=C(Cl)c1cccc(Cl)c1>>CCOC(=O)CC1CCN(c2nc(S(C)(=O)=O)ccc2NC(=O)c2cccc(Cl)c2)CC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US05254578,CC1(C)Oc2ccc(S(=O)(=O)C(F)(F)F)cc2C2OC21.COc1ccc[nH]c1=O>>COc1cccn([C@@H]2c3cc(S(=O)(=O)C(F)(F)F)ccc3OC(C)(C)[C@H]2O)c1=O,,CS(C)=O,,[H-].[Na+],,test
US20030032647A1,CCN(CC)CC.CCOC(=O)c1cnc(Cl)nc1NCc1ccc(OC)c(Cl)c1>>c1cn2c(n1)CNCC2,,ClC(Cl)Cl,,,,test
US20140206663A1,CC1C(=O)NN=C2COc3cc(OCc4ccccc4)c([N+](=O)[O-])cc3N21>>CC1C(=O)NN=C2COc3cc(OCc4ccccc4)c(N)cc3N21,[Ni],CO,,,,test
US04661602,CCCCCCCCNC(C)N.Cc1ccccc1S(=O)(=O)O>>CCCCCCCCNC(C)N.Cc1ccc(S(=O)(=O)O)cc1,,CC(C)O,O,,,test
US05578593,CC(C)(C)OC(=O)N1CCC2(CC1)CC(N)c1ccccc12.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC2(CC1)CC(NS(C)(=O)=O)c1ccccc12,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US04225618,Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C=NC(=O)CCl>>O=C(CCl)NC(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1,,Cc1ccccc1,,,,test
US20100105744A1,CCO.CCSCc1cccc2c(C(c3ccc(Cl)cc3)C3C(=O)OC(C)(C)OC3=O)c[nH]c12>>CCOC(=O)CC(c1ccc(Cl)cc1)c1c[nH]c2c(CSCC)cccc12,[Cu],CCO,c1ccncc1,,,test
US20120252801A1,CCN1CC(CC)(CC)OC(=O)C1CC(=O)OC(C)(C)C>>CCN1CC(CC)(CC)OC(=O)C1CC(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US06307069B1,CCCCCCC(=O)CCCCCC.OCC(O)CO>>CCCCCCC1(CCCCCC)OCC(CO)O1,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,,,test
US20070244095A1,Cc1cc2c(cc1C(F)(F)F)N(C(=O)OC(C)(C)C)CCC[C@@H]2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1>>Cc1cc2c(cc1C(F)(F)F)NCCC[C@@H]2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20110251225A1,COC(=O)C1(CCC=O)CCOCC1.C[C@H]1CCCN1[C@H]1CCN(c2ccc(N)c(F)c2)C1>>COC(=O)C1(CCCNc2ccc(N3CC[C@H](N4CCC[C@@H]4C)C3)cc2F)CCOCC1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20110245205A1,CCOC(=O)C1CCC(OC)(c2ncc(-c3cc(C)cc(N(C(=O)OC(C)(C)C)c4nccc(C(F)(F)F)n4)c3)s2)CC1>>CCOC(=O)C1CCC(OC)(c2ncc(-c3cc(C)cc(Nc4nccc(C(F)(F)F)n4)c3)s2)CC1,,ClCCl,O,O=C(O)C(F)(F)F,,test
US20060100229A1,C=CS(C)(=O)=O.CCn1nc(C#N)c(Br)c1CC(C)(C)N>>CCn1nc(C#N)c(Br)c1CC(C)(C)NCCS(C)(=O)=O,,Cc1ccccc1,,,,test
US20140228555A1,CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O.N#C[S-]>>CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O.N#CS,,CC(=O)O,,O,,test
US20040053908A1,CN1CCCC(COc2cc3nccc(Oc4ccc(N)c(Cl)c4)c3cc2C#N)C1.NC1CC1.O=C(Cl)Oc1ccccc1>>CN1CCCC(COc2cc3nccc(Oc4ccc(NC(=O)NC5CC5)c(Cl)c4)c3cc2C#N)C1,,CCOC(C)=O,CN(C)C=O,c1ccncc1,O=C([O-])O.[Na+],test
US20050176727A1,Brc1ccccn1.C[C@H]1CNCCN1>>C[C@H]1CN(c2ccccn2)CCN1,,O,,,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Nc1ccc2c(O)ncnc2c1>>COc1ccc2nc(Nc3ccc4c(O)ncnc4c3)c3[nH]ncc3c2c1,C1COCCO1,CO,,Cl,,test
US20090048230A1,C=CCO.CSc1nc(Cl)c(C(=O)O)c(Cl)n1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>C=CCOC(=O)Nc1c(Cl)nc(SC)nc1Cl,,C1COCCO1,CCOC(C)=O,CCN(CC)CC,,test
US20080139639A1,CN.CS(=O)(=O)c1cccc(S(=O)(=O)n2cc(C=O)cc2-c2ccccc2F)c1.Cl>>CNCc1cc(-c2ccccc2F)n(S(=O)(=O)c2cccc(S(C)(=O)=O)c2)c1.Cl,,CO,,[BH4-].[Na+],,test
US20030069425A1,CCOC(=O)C(C(=O)c1ccncc1)c1ccc(F)cc1.N=C(N)CCCCc1ccccc1>>O=c1[nH]c(CCCCc2ccccc2)nc(-c2ccncc2)c1-c1ccc(F)cc1,,Cc1ccc(C)cc1,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US04324801,CC(=O)Oc1ccccc1C(=O)O.CCOC(=O)c1ccc(NC(=N)N)cc1O>>CC(=O)Oc1ccccc1C(=O)O.CCOC(=O)c1ccc(NC(=N)N)cc1O,,ClC(Cl)Cl,,,,test
US04892881,CCOC(=O)CC(=O)COCC1COC(C)(C)O1.O=Cc1cccc(Cl)c1Cl>>CCOC(=O)C(=Cc1cccc(Cl)c1Cl)C(=O)COCC1COC(C)(C)O1,,CC(C)O,,C1CCNCC1,,test
US20080194549A1,COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN(C(=O)Cc2cccc([N+](=O)[O-])c2)C2CC2)C(C)C)ccc1OC>>COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN(C(=O)Cc2cccc(N)c2)C2CC2)C(C)C)ccc1OC,[Ni],,,,,test
US06255494B1,C=CCc1cccc2c1nc(COc1ccc(Cl)cc1)n2CCCC1CCN(C(=O)OC(C)(C)C)CC1>>CCCc1cccc2c1nc(COc1ccc(Cl)cc1)n2CCCC1CCN(C(=O)OC(C)(C)C)CC1,[Pd],CCOC(C)=O,,[H][H],,test
US20110275611A1,Cc1cccc(NC(=O)[C@H]2CCCN(c3cc(-c4ccc(C#N)c(F)c4)nc(N)n3)C2)c1.NN>>Cc1cccc(NC(=O)[C@H]2CCCN(c3cc(-c4ccc5c(N)n[nH]c5c4)nc(N)n3)C2)c1,,CCO,,CCN(C(C)C)C(C)C,,test
US20090105244A1,Cc1c(Cl)c(S(C)=O)nc2sc(C(=O)NC3CC3)c(N)c12.OCCOCCN1CCNCC1>>Cc1c(Cl)c(OCCOCCN2CCNCC2)nc2sc(C(=O)NC3CC3)c(N)c12,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US07091199B1,BrCCCOc1cccc(-c2noc3ccsc23)c1.NC12CC3CC(CC(C3)C1)C2>>c1cc(OCCCNC23CC4CC(CC(C4)C2)C3)cc(-c2noc3ccsc23)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140155389A1,COc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1cc(Cc2cc(F)ccc2F)nc2cn[nH]c(=O)c12.O=C(O)C(F)(F)F>>COc1cc(C2CCNCC2)ccc1Nc1cc(Cc2cc(F)ccc2F)nc2cn[nH]c(=O)c12.O=C([O-])C(F)(F)F,,ClCCl,,,,test
US20100137368A1,FC(F)(F)c1ccc(NC2CCNCC2)nc1.Fc1ccc(CBr)cc1F>>Fc1ccc(CN2CCC(Nc3ccc(C(F)(F)F)cn3)CC2)cc1F,,CC#N,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20120065195A1,CCOC(=O)C(C(=O)OCC)C(C)(C)Cc1ccc(Br)cc1>>CC(C)(Cc1ccc(Br)cc1)C(C(=O)O)C(=O)O,,O,,CCO,[K+].[OH-],test
US20160108047A1,CCOC(=O)c1nc(C2=CCN(C)CC2)n(C(C)C)c1C(N=[N+]=[N-])c1ccc(Cl)cc1>>CCOC(=O)c1nc(C2=CCN(C)CC2)n(C(C)C)c1C(N)c1ccc(Cl)cc1,[Ni],CCO,,,,test
US20150197511A1,Nc1cc(NC(=O)CCCCl)cc(C(F)(F)F)c1>>Nc1cc(N2CCCC2=O)cc(C(F)(F)F)c1,,C1CCOC1,,[H-].[Na+],,test
US20100249119A1,Cc1ccc(Oc2ccc3nc(N)sc3n2)cc1NC(=O)c1cccc(C(C)(C)C#N)c1.O=C(Cl)c1cocn1>>Cc1ccc(Oc2ccc3nc(NC(=O)c4cocn4)sc3n2)cc1NC(=O)c1cccc(C(C)(C)C#N)c1,,c1ccncc1,,,,test
US20040122244A1,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)O)c2)=C(C)C1=O.Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)Nc3cc(C(F)(F)F)cc(C(F)(F)F)c3)c2)=C(C)C1=O,,ClCCl,,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US20020095050A1,COC(=O)[C@H](COc1cccc(-c2cccc(NC(=O)NCc3ccccn3)c2)c1)NC(c1ccccc1)(c1ccccc1)c1ccccc1.Cl>>COC(=O)[C@@H](N)COc1cccc(-c2cccc(NC(=O)NCc3ccccn3)c2)c1.Cl,,C1COCCO1,,,,test
US20090054435A1,BrCc1ccccc1.COc1ccc(C(=O)c2ccc(Cl)nc2)c(O)c1>>COc1ccc(C(=O)c2ccc(Cl)nc2)c(OCc2ccccc2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US03974161,CCOC(=O)C(=O)OCC.NC(=O)c1cc2ccc(F)cc2nc1N>>CCOC(=O)c1nc2nc3cc(F)ccc3cc2c(=O)[nH]1,,CCCCCC,,,,test
US04602027,CC1(C(=O)Cl)CCCCC1.ClCCl.N[C@@H](CC(=O)OCc1ccccc1)C(=O)O>>CC(=O)C(CC(=O)OCc1ccccc1)NC(=O)C1(C)CCCCC1,,CCN(CC)CC,,,,test
US20120046269A1,CC(C)(C)OC(=O)Nc1nc(C(=O)Nc2cccc(CNc3ncnc4c(C(N)=O)cccc34)c2)cs1>>NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4csc(N)n4)c3)ncnc12,,C1COCCO1,,Cl,,test
US20140349990A1,CNc1nc(Cl)ccc1N.O=N[O-]>>Cn1nnc2ccc(Cl)nc21,,Cl,,[Na+].[OH-],,test
US20120277205A1,Brc1ccc2[nH]ccc2c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(c1c[nH]c2ccc(Br)cc12)C(F)(F)F,,CCOCC,,,,test
US20130102576A1,COC(=O)CN1CCc2cc(OC)c(OC)cc2C1.Cl>>COc1cc2c(cc1OC)CN(CC(=O)O)CC2.Cl,,C1COCCO1,,,,test
US20110178132A1,COc1ccc(-c2ccnc(C(N)=NO)c2)c(C(F)(F)F)c1.O=C(n1ccnc1)n1ccnc1>>COc1ccc(-c2ccnc(-c3nc(=O)o[nH]3)c2)c(C(F)(F)F)c1,,C1CCOC1,O,C1CCC2=NCCCN2CC1,Cl,test
US05536721,COC(=O)c1cc2c3cc(Cl)ccc3n(C)c2s1>>Cn1c2ccc(Cl)cc2c2cc(C(=O)O)sc21,,CCOC(C)=O,Cc1ccccc1,Cl,[K+].[OH-],test
US20130178420A1,CC(C)(C)c1ccc(C(=O)O)cc1.CCCCCCCOc1ccc(-c2c[nH]c(-c3ccc(C[C@H](N)C(=O)OC)cc3)n2)cc1>>CCCCCCCOc1ccc(-c2c[nH]c(-c3ccc(C[C@H](NC(=O)c4ccc(C(C)(C)C)cc4)C(=O)OC)cc3)n2)cc1,,CN(C)C=O,ClCCl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US04908357,C1N2CN3CN1CN(C2)C3.O=C(CBr)c1cccs1>>O=C(C[N+]12CN3CN(CN(C3)C1)C2)c1cccs1.[Br-],,ClC(Cl)Cl,,,,test
US03959375,OC1CC(O)C2CC1NN2>>N[C@H]1C[C@@H](N)[C@H](O)C[C@@H]1O,[Ni],CCO,,O,,test
US20050288340A1,COC(=O)c1cc(S(=O)(=O)NCCc2coc(-c3ccc(C(C)(C)C)cc3)n2)ccc1C>>Cc1ccc(S(=O)(=O)NCCc2coc(-c3ccc(C(C)(C)C)cc3)n2)cc1C(=O)O,,CO,,[Na+].[OH-],,test
US20030207877A1,CC(=O)c1cc2ccccc2o1.CC(C)[Si](OS(=O)(=O)C(F)(F)F)(C(C)C)C(C)C>>C=C(O[Si](C(C)C)(C(C)C)C(C)C)c1cc2ccccc2o1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090163489A1,Cc1ccc(S(=O)(=O)Nc2ccc(Br)cn2)cc1.NC(=O)CBr>>Cc1ccc(S(=O)(=O)N=c2ccc(Br)cn2CC(N)=O)cc1,,O,,CCN(C(C)C)C(C)C,CN(C)C=O,test
US20090286812A1,CC(C)C(=N)NO.CCOC(=O)C1CCC(=O)CC1>>CC(C)c1noc(C2CCC(=O)CC2)n1,,C1CCOC1,,[H-].[Na+],,test
US20070259896A1,C=CCC[Mg]Br.Fc1ccc(-c2csc3ncnc(Cl)c23)cc1>>C=CCCc1ncnc2scc(-c3ccc(F)cc3)c12,[Cu]I,C1CCOC1,,,,test
US05446060,CC1CCCNC1.O=C(CCCl)Cc1cccs1>>CC1CCCN(CCC(=O)Cc2cccs2)C1.Cl,,CCOCC,Cc1ccccc1,,,test
US03932479,C#CCCC.O=CCCCl>>CCCC#CC(O)CCCl,,CCCCCC,,[Li]CCCC,[Cl-].[NH4+],test
US07015218B1,CC(C)(C)COc1ccc(N)cc1Br.Cc1nn(-c2ccc(F)cc2)cc1C(=O)O>>Cc1nn(-c2ccc(F)cc2)cc1C(=O)Nc1ccc(OCC(C)(C)C)c(Br)c1,,CN(C)C=O,O,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20050288273A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCC(C(=O)c2ccc(C#N)cc2)C3=O)C(=O)O1.NN>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCc2c(-c4ccc(C#N)cc4)n[nH]c2-3)C(=O)O1,,CCO,,O,,test
US20080027107A1,N#CCBr.OCC1CCCN1>>N#CCN1CCCC1CO,,C1CCOC1,,CCN(CC)CC,,test
US20100227864A1,CCOC(=O)c1cc(Br)ncc1F.OCc1ccccc1>>CCOC(=O)c1cc(Br)ncc1OCc1ccccc1,,C1CCOC1,,O,[H-].[Na+],test
US20100168418A1,CC(C)c1ccc2c(ccc(=O)n2CCN2CCC(N(Cc3ccc4c(c3)OCCO4)C(=O)OC(C)(C)C)CC2)c1.Cl>>CC(C)c1ccc2c(ccc(=O)n2CCN2CCC(NCc3ccc4c(c3)OCCO4)CC2)c1.Cl,,C1COCCO1,,,,test
US20100292475A1,BrBr.C=COCC.COc1ccc(C=O)c(-c2ccc(O[Si](C(C)C)(C(C)C)C(C)C)cc2)c1O>>CCOC(CBr)Oc1c(OC)ccc(C=O)c1-c1ccc(O[Si](C(C)C)(C(C)C)C(C)C)cc1,,ClCCl,,CC(C)NC(C)C,,test
US20080004309A1,CCOC(=O)CNC(=O)OC(C)(C)C.CCOC(=O)c1sc(-c2ccc(C(F)(F)F)cc2)nc1CBr>>CCOC(=O)CN(Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(=O)OCC)C(=O)OC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20130338134A1,O=Cc1cnc2[nH]ccc2c1Cl.O=S(=O)(Cl)c1ccccc1>>O=Cc1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1Cl,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080085886A1,CCOC(=O)c1oc2ncncc2c1Nc1ccc([Si](C)(C)C)cc1F.ClI>>CCOC(=O)c1oc2ncncc2c1Nc1ccc(I)cc1F,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20110003787A1,CC(C)[Si](Cl)(C(C)C)C(C)C.COC[C@H](C)Oc1cc(O[Si](C(C)C)(C(C)C)C(C)C)cc(-c2ccc(C(=O)NC[C@H](O)CO)[nH]2)c1>>COC[C@H](C)Oc1cc(O[Si](C(C)C)(C(C)C)C(C)C)cc(-c2ccc(C(=O)NC[C@H](O)CO[Si](C(C)C)(C(C)C)C(C)C)[nH]2)c1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US20140350019A1,CI.O=[N+]([O-])c1c(Cl)ccc(O)c1Cl>>COc1ccc(Cl)c([N+](=O)[O-])c1Cl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04182730,CCC(=O)c1ccc(OC)cc1.CN(C)C=O.O=P(Cl)(Cl)Cl>>COc1ccc(C(Cl)=C(C)C=O)cc1,,Cc1ccccc1,,CC(=O)[O-].[Na+],,test
US20100317624A1,CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2ccc3c(=O)c(C(=O)O)cn(CC)c3c2)cn1.NCCCOP(=O)(O)O>>CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2ccc3c(=O)c(C(=O)NCCCOP(=O)(O)O)cn(CC)c3c2)cn1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100249110A1,CSc1nc2c3c(n[nH]c3n1)C(C(=O)O)CN2Cc1ccccc1.NCc1ccccc1>>CSc1nc2c3c(n[nH]c3n1)C(C(=O)NCc1ccccc1)CN2Cc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160120841A1,COCCOc1ccc2c(c1)O[C@@H](c1cccc(C(=O)OC)c1)C[C@H]2NC(=O)C1(c2ccc3c(c2)OC(F)(F)O3)CC1>>COCCOc1ccc2c(c1)O[C@@H](c1cccc(C(=O)O)c1)C[C@H]2NC(=O)C1(c2ccc3c(c2)OC(F)(F)O3)CC1,,CO,O,[Li+].[OH-],,test
US20120295884A1,COC(=O)Cn1nc(C(C)=O)c2cc(OCc3ccccc3)ccc21>>COC(=O)Cn1nc(C(C)=O)c2cc(O)ccc21,[Pd],C1CCOC1,,,,test
US20110172187A1,C=C(C=C1CCOB1O)NS(=O)(=O)c1ccc([N+](=O)[O-])cc1C.CO>>Cc1cc(N)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2,[Pd],,,,,test
US20150210678A1,Cc1csc(B(O)O)c1.Cn1nc(C(F)F)c(C(=O)N(Cc2ccccc2Br)C2CC2)c1F>>Cc1csc(-c2ccccc2CN(C(=O)c2c(C(F)F)nn(C)c2F)C2CC2)c1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20070066606A1,O=Cc1ccc(F)c([N+](=O)[O-])c1>>O=[N+]([O-])c1cc(CO)ccc1F,,CCCCCCC,,[BH4-].[Na+],,test
US04032323,CCCOC(=O)CC(C)=O.N>>CCCOC(=O)CC(C)=N,,CCOCC,,,,test
US04492692,CC(=O)OCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)C(Nc3nc(Cc4ccccc4)c[nH]3)[C@H]2SC1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C(O)C1=CCS[C@@H]2C(Nc3nc(Cc4ccccc4)c[nH]3)C(=O)N12,,COc1ccccc1,,,,test
US06797726B1,CC(=O)c1cc(CCOCCN(C)C)ccc1O.CCOC=O>>CN(C)CCOCCc1ccc2occc(=O)c2c1,,CCOC(C)=O,Cc1ccccc1,[H-].[Na+],O=C([O-])[O-].[K+].[K+],test
US20110281838A1,CNc1ccc(C#Cc2c(C)nc(N)nc2-c2ccc(C(=O)OC)c(Cl)c2)cn1>>CNc1ccc(C#Cc2c(C)nc(N)nc2-c2ccc(C(=O)O)c(Cl)c2)cn1,,C1CCOC1,,,,test
US20050148624A1,CS(=O)(=O)c1ccc(Cn2c(C(=O)O)c(-c3ccccc3)c3cc(Br)ccc3c2=O)cc1>>CS(=O)(=O)c1ccc(Cn2c(CO)c(-c3ccccc3)c3cc(Br)ccc3c2=O)cc1,,C1CCOC1,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20110288076A1,BrCc1ccccc1.N[C@@H]1C[C@@H](C(=O)Nc2ccc(Oc3ccc(F)cc3)cc2)N(C(=O)Cn2cncn2)C1>>O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)[C@@H]1C[C@@H](NCc2ccccc2)CN1C(=O)Cn1cncn1,,CO,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100273806A1,CCOC(=O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cc(C#C[Si](C)(C)C)cc(OC(F)(F)F)c4)n3)cc21>>C#Cc1cc(OC(F)(F)F)cc(-c2nc(-c3ccc4[nH]c5c(c4c3)CCC5CC(=O)O)no2)c1,,C1CCOC1,CO,[Na+].[OH-],,test
US20080004245A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.COc1ccc2cc(C(C)C(=O)Oc3ccc(C(N)=O)cc3)ccc2c1>>COc1ccc2cc(C(C)C(=O)Oc3ccc(C(N)=S)cc3)ccc2c1,,c1ccccc1,,,,test
US20130045986A1,CCCS(=O)(=O)Cl.NC(=O)c1ccc(-c2ccc3oc(C4CCNCC4)nc3c2)cc1F>>CCCS(=O)(=O)N1CCC(c2nc3cc(-c4ccc(C(N)=O)c(F)c4)ccc3o2)CC1,,ClCCl,,O,,test
US20150133457A1,COCCN1CCN(c2ccc([N+](=O)[O-])cc2F)CC1>>COCCN1CCN(c2ccc(N)cc2F)CC1,[Pd],C1CCOC1,,[H][H],,test
US20090312381A1,COC(=O)CCl.O=c1[nH]nc(Br)n1Cc1ccccc1F>>COC(=O)Cn1nc(Br)n(Cc2ccccc2F)c1=O,,CC#N,CCOC(C)=O,Cl,O=C([O-])[O-].[K+].[K+],test
US20110028467A1,Nc1cnccc1O.O=C(Cl)CCl>>O=C1COc2ccncc2N1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US07399759B2,C1CCNCC1.O=c1nc(-c2cccc(CS(=O)(=O)[O-])n2)sc2ccccc12>>O=c1nc(-c2cccc(CN3CCCCC3)n2)sc2ccccc12,,CN(C)C=O,O,CCN(CC)CC,CCOC(C)=O,test
US20140329876A1,CCN(CC)S(F)(F)F.COCCO[C@@H]1C(c2ccc(C#N)c(Cl)c2C)=NN2CC[C@H](O)[C@@H]12>>COCCO[C@@H]1C(c2ccc(C#N)c(Cl)c2C)=NN2CC[C@@H](F)[C@@H]12,,ClCCl,O,,,test
US20130065877A1,CC(C)(C)[Si](C)(C)OC1CCC(c2ccc(N)c(F)c2)CC1.O=C(Cl)OCc1ccccc1>>CC(C)(C)[Si](C)(C)OC1CCC(c2ccc(NC(=O)OCc3ccccc3)c(F)c2)CC1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20040198773A1,Cc1ccncc1C(=O)CCl.O=C(O)c1ccc(Cl)cc1>>Cc1ccncc1C(=O)COC(=O)c1ccc(Cl)cc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100160326A1,FC(F)(F)c1cc(Br)nc(N(Cc2ccccn2)Cc2ccccn2)c1.O=C1CCC(=O)N1Cl>>FC(F)(F)c1cc(N(Cc2ccccn2)Cc2ccccn2)nc(Br)c1Cl,,CN(C)C=O,,O,,test
US20070244125A1,O=C(c1cc2cc(Br)ccc2[nH]1)N1CCOCC1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>O=C(c1cc2cc(Br)ccc2n1CC(F)(F)F)N1CCOCC1,,C1CCOC1,,[H-].[Na+],,test
US20080280923A1,COC(=O)c1cc(C(C)(C)C)ccc1OC>>COc1ccc(C(C)(C)C)cc1CO,,CCOCC,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20020103229A1,CCOC(=N)c1ccc2[nH]nc(-c3ccc(F)cc3)c2c1.CN(C)CC(=O)NN>>CN(C)Cc1nnc(-c2ccc3[nH]nc(-c4ccc(F)cc4)c3c2)[nH]1,,CCO,,CCN(CC)CC,Cl,test
US20090099176A1,N#CCN1C(=O)C(NC(=O)c2cc3cc(Cl)ncc3[nH]2)Cc2ccccc21.[N-]=[N+]=[N-]>>O=C(NC1Cc2ccccc2N(Cc2nnn[nH]2)C1=O)c1cc2cc(Cl)ncc2[nH]1,,CN1CCCC1=O,,CCN(CC)CC,Cl,test
US03988471,C=CCBr.CC(C)(C)c1cccc(C(C)(C)C)c1O.S=C=S>>C=CCSC(=S)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1,,COCCOC,,Cl,[H-].[Na+],test
US20070287708A1,CCCC[Sn](CCCC)(CCCC)c1cc2cc(C=O)ccc2o1.Cc1c(Nc2c(I)cncc2C#N)cc(Cl)c2[nH]ccc12>>Cc1c(Nc2c(C#N)cncc2-c2cc3cc(C=O)ccc3o2)cc(Cl)c2[nH]ccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,CCOC(C)=O,,test
US20120225862A1,CC(C)(C)c1ccc(S(=O)(=O)NCc2ccc(C(=O)O)cc2)cc1.Nc1cncc(F)c1>>CC(C)(C)c1ccc(S(=O)(=O)NCc2ccc(C(=O)Nc3cncc(F)c3)cc2)cc1,CN(C)C=O,C1CCOC1,,O=C(Cl)C(=O)Cl,,test
US20160222030A1,BrCc1ccc2ccccc2n1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>[Br-].c1ccc([P+](Cc2ccc3ccccc3n2)(c2ccccc2)c2ccccc2)cc1,,Cc1ccccc1,,,,test
US20120214794A1,C=CCC1(C(=O)OC)NC(=O)c2sc(N3CCOCC3)cc2C1c1ccc(Cl)c(Cl)c1>>C=CCC1(C(=O)O)NC(=O)c2sc(N3CCOCC3)cc2C1c1ccc(Cl)c(Cl)c1,,C1CCOC1,CO,O,[Na+].[OH-],test
US20100105653A1,CCOC(C#Cc1cnc(Cl)nc1NC1CCCC1)OCC>>CCOC(OCC)c1cc2cnc(Cl)nc2n1C1CCCC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20060172983A1,CC(=O)Nc1ccc(O)cc1.CCOC(=O)CBr>>CCOC(=O)COc1ccc(NC(C)=O)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05696148,CCOC(=O)CC#N.COc1ccc(CN2c3ccccc3CC2(Cl)C=O)cc1>>CCOC(=O)C(C#N)=Cc1c(Cl)n(Cc2ccc(OC)cc2)c2ccccc12,,CCO,,O,O=C([O-])[O-].[K+].[K+],test
US05221665,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.CCOC(=O)CNCc1ccccc1>>CCOC(=O)CN(Cc1ccccc1)C(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C,CN(C)c1ccncc1,ClCCl,,CCOC(C)=O,,test
US20090197856A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COCOCCn1c(-c2cccc3c2NC(=O)C(C)(C)[C@H]3N[S@@](=O)C(C)(C)C)c(C2CCCCC2)c2ccc(C(=O)OC)cc21>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3cccc4c3NC(=O)C(C)(C)[C@H]4NC(=O)OC(C)(C)C)n(CCO)c2c1,,C1COCCO1,CO,CCN(C(C)C)C(C)C,Cl,test
US20140256936A1,COc1ccc2c(C3=C(c4c(-c5ccc(C(C)(C)C)cc5)oc5cc(OC)ccc45)C(F)(F)C(F)(F)C3(F)F)c(-c3ccc(C(C)(C)C)cc3)oc2c1>>CC(C)(C)c1ccc(-c2oc3cc(O)ccc3c2C2=C(c3c(-c4ccc(C(C)(C)C)cc4)oc4cc(O)ccc34)C(F)(F)C(F)(F)C2(F)F)cc1,,ClCCl,,BrB(Br)Br,,test
US20070161673A1,Cc1ccc(C(=O)NC2CC2)cc1-c1cc2cn[nH]c2cn1.O=S(=O)(Cl)c1cccs1>>Cc1ccc(C(=O)NC2CC2)cc1-c1cc2cnn(S(=O)(=O)c3cccs3)c2cn1,,CN(C)C=O,,[H-].[Na+],,test
US07851623B2,CN1CCCC1=O.COC(C)(C)C.COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1O>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCCC1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20140350005A1,COC(=O)CC(c1ccccc1)N1CN(c2ccccc2)C2(CCN(CCCn3c(=O)[nH]c4ccccc43)CC2)C1=O>>O=C(O)CC(c1ccccc1)N1CN(c2ccccc2)C2(CCN(CCCn3c(=O)[nH]c4ccccc43)CC2)C1=O,,CO,O,[Li+].[OH-],,test
US06060475,CC(=O)O.COc1nc(C)cnc1NS(=O)(=O)c1cccnc1-c1ccc(CC(C)CO[Si](C)(C)C(C)(C)C)cc1>>COc1nc(C)cnc1NS(=O)(=O)c1cccnc1-c1ccc(CC(C)COC(C)=O)cc1,,CC(=O)OC(C)=O,,O=C([O-])O.[Na+],,test
US04800201,CC1=CSC(C)C(=O)N1.O=C(Cl)OCC(Cl)(Cl)Cl.c1ccncc1>>CC1=C(C2C=CN(C(=O)OCC(Cl)(Cl)Cl)C=C2)SC(C)C(=O)N1,,CC#N,,,,test
US20090214675A1,C/C(N)=C/C(=O)OC1CCCC1.CC([O-])=CC#N.Cc1cc(=O)c2cccc(C=O)c2o1>>CC1=C(C#N)C(c2cccc3c(=O)cc(C)oc23)C(C(=O)OC2CCCC2)=C(C)N1,,CC(C)O,,CC(=O)O,,test
US20050176859A1,C=O.CC(C)(C)c1ccc(O)c(C(C)(C)C)c1.CNC>>CN(C)Cc1cc(C(C)(C)C)cc(C(C)(C)C)c1O,,CCO,,,,test
US03976786,Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1.O=C(OC(=O)C1CC1)C1CC1>>O=C(Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1)C1CC1,O=S(=O)(O)O,CCOCC,,,,test
US20020137689A1,CCCCCCCCCC(I)I.O=C1C(CCC(O)c2ccc(F)cc2)C(c2ccc(O)cc2)N1c1ccc(F)cc1>>O=C1C(CCC(O)c2ccc(F)cc2)C(c2ccc(OCCCCCCCCCCI)cc2)N1c1ccc(F)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050192287A1,COCCN1CCC(C(=O)Nc2cc(Oc3ccc4c(c3)nc(Nc3cc(C(F)(F)F)ccc3F)n4C)ccn2)CC1>>Cn1c(Nc2cc(C(F)(F)F)ccc2F)nc2cc(Oc3ccnc(NC(=O)C4CCN(CCO)CC4)c3)ccc21,,ClCCl,,,,test
US05703050,CC(C)(C)OC(=O)NN=Cc1ccc(NC(=O)NCC(=O)NC(CC(=O)OCc2ccccc2)c2ccccc2)cc1>>NN=Cc1ccc(NC(=O)NCC(=O)NC(CC(=O)O)c2ccccc2)cc1,[Pd],CN(C)C=O,,[H][H],,test
US07160901B2,CC(=O)OC(C)=O.O=C(NCCNc1ccc([N+](=O)[O-])cc1)C(F)(F)F>>CC(=O)N(CCNC(=O)C(F)(F)F)c1ccc([N+](=O)[O-])cc1,,CC(=O)O,,,,test
US20050171179A1,CCOC(=O)C1=NN(c2ccc(Cl)cc2)C(c2ccccc2)C1>>O=C(O)C1=NN(c2ccc(Cl)cc2)C(c2ccccc2)C1,,CO,,O,[Na+].[OH-],test
US20090312544A1,N#CC(NNC(=N)N)c1cccc(Cl)c1Cl>>Nc1nnc(-c2cccc(Cl)c2Cl)c(N)n1,,CCCO,,C,,test
US20100029753A1,CCC(C)c1ccccc1.O=S(=O)(O)Cl>>CCC(C)c1ccc(S(=O)(=O)Cl)cc1,,ClCCCl,,ClP(Cl)(Cl)(Cl)Cl,,test
US20140329816A1,COC(=O)C1CC(=O)CN1C(=O)OC(C)(C)C.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)C1CC(OS(=O)(=O)C(F)(F)F)=CN1C(=O)OC(C)(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20120264923A1,CC(=CCCC(=O)OCC(CO)(CO)CO)CCCC(C)CCCC(C)CCCC(C)C.O>>CC(=CCCC(=O)OCC(CO)(CO)CO)CCCC(C)CCCC(C)CCCC(C)C.O,,O,,,,test
US20150307451A1,COC(=O)c1cc(Br)c(OC)c(Cl)c1O.COCCl>>COCOc1c(C(=O)OC)cc(Br)c(OC)c1Cl,,C1CCOC1,,O,[H-].[Na+],test
US20160152605A1,COC(=O)c1ccc([C@@H]2C[C@@H](OC)CCN2)cc1.COc1cc(C)c2c(ccn2C(=O)OC(C)(C)C)c1C=O>>COC(=O)c1ccc([C@@H]2C[C@@H](OC)CCN2Cc2c(OC)cc(C)c3c2ccn3C(=O)OC(C)(C)C)cc1,,ClCCCl,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20120214769A1,COC(=O)c1ccc(C=O)cc1.COP(=O)(OC)C(Br)C(=O)OCc1ccccc1>>COC(=O)c1ccc(C=C(Br)C(=O)OCc2ccccc2)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20060128639A1,COC(=O)C(F)(F)F.NCCCCCCCCCCCC(=O)O>>O=C(O)CCCCCCCCCCCNC(=O)C(F)(F)F,,CCOC(C)=O,CO,CCN(CC)CC,Cl,test
US20090118201A1,Cc1ccc(S(=O)(=O)OCC#CC2CC2)cc1.OC[C@H]1O[C@@H](c2ccc(Cl)c(Cc3ccc(O)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O>>OC[C@H]1O[C@@H](c2ccc(Cl)c(Cc3ccc(OCC#CC4CC4)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050101587A9,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.Nc1ccc(Cl)cc1C=O>>CCOC(=O)C=Cc1cc(Cl)ccc1N,,CCOCC,c1ccccc1,,,test
US20050267093A1,CCN(CC)CCOc1ccc([N+](=O)[O-])cc1C>>CCN(CC)CCOc1ccc(N)cc1C,[Ni],CCOC(C)=O,,,,test
US20130317001A1,CC(C)(O)c1cc(C(=O)NS(=O)(=O)N2CCC2)c(F)cc1OCC12CC3CC(CC(C3)C1)C2.CCN(CC)S(F)(F)F>>CC(C)(F)c1cc(C(=O)NS(=O)(=O)N2CCC2)c(F)cc1OCC12CC3CC(CC(C3)C1)C2,,ClCCl,,CC#N,O,test
US04863904,CCOC(=O)CC#N.O=Cc1cccc2ccccc12>>CCOC(=O)C(C#N)=Cc1cccc2ccccc12,,c1ccccc1,,C1CCNCC1,CC(=O)O,test
US20050026928A1,CC(C)[C@@H](NC(=O)OC(C)(C)C)C(=O)O.CN1CCC(N2CCNCC2)CC1>>CC(C)[C@@H](NC(=O)OC(C)(C)C)C(=O)N1CCN(C2CCN(C)CC2)CC1,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20070078164A1,CN(C)C=O.COCCCCc1cccc(Br)c1>>COCCCCc1cccc(C=O)c1,,C1CCOC1,,Cl,[Li]CCCC,test
US20100152163A1,CC(=CBr)c1ccc(Cl)cc1Cl.Cc1ccc2[nH]c3c(c2c1)CCN(C)CC3>>C/C(=C/n1c2c(c3cc(C)ccc31)CCN(C)CC2)c1ccc(Cl)cc1Cl,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20120178715A1,CC(C)(C)OC(=O)N1CCC(C(N)C(=O)O)CC1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NC(C(=O)O)C1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20110166116A1,CC(C)OC(=O)N1CCC(ON=C2CCN(c3cc(N)c(N)cc3F)CC2)CC1.COC(OC)OC>>CC(C)OC(=O)N1CCC(ON=C2CCN(c3cc4[nH]cnc4cc3F)CC2)CC1,,CN(C)C=O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20110319392A1,CC(C)c1nc(-c2cccc(N)c2)c(-c2ccnc(Cl)n2)s1.O=S(=O)(Cl)c1ccc(F)cc1>>CC(C)c1nc(-c2cccc(NS(=O)(=O)c3ccc(F)cc3)c2)c(-c2ccnc(Cl)n2)s1,,ClCCl,,c1ccncc1,,test
US20150361067A1,CCC(O)c1cc(Cl)c2c(c1Cl)C(=O)N(Cc1c(C)cc(C)nc1OCc1ccccc1)CC2.CI>>CCC(OC)c1cc(Cl)c2c(c1Cl)C(=O)N(Cc1c(C)cc(C)nc1OCc1ccccc1)CC2,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20150210682A1,CCOC(=O)c1cn2c(cc1=O)-c1cc(Cl)c(OCCCOC)cc1CC2C(C)(C)C>>COCCCOc1cc2c(cc1Cl)-c1cc(=O)c(C(=O)O)cn1C(C(C)(C)C)C2,,CO,O,Cl,[Li]O,test
US20080261920A1,ClCCl.II.OCC1(c2ccc(Cl)cc2)CC1>>Clc1ccc(C2(CI)CCC2)cc1,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040122244A1,COc1c(C)c(Cc2ccc(OCc3ccccc3)c(C(=O)N3CCCCC3)c2)c(OC)c(OC)c1OC>>COc1c(C)c(Cc2ccc(O)c(C(=O)N3CCCCC3)c2)c(OC)c(OC)c1OC,[Pd],CCO,,[H][H],,test
US20120015950A1,CC(C)(C)OC(=O)N1CCC(=CC(=O)OCCC#N)CC1.CC[Mg]Br>>CCC1(CC(=O)OCCC#N)CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,CCOCC,CCOC(C)=O,[Cl-].[NH4+],test
US05359052,CC(C)NC(C)C.ClP1OCCS1>>CC(C)N(C(C)C)P1OCCS1,,CCCCC,,,,test
US20080027068A1,COC(=O)c1ccc(C(=O)NN=C(C)c2csc(-c3ccc(C(C)(C)C)cc3)c2O)cc1NC(C)=O>>CC(=O)Nc1cc(C(=O)NN=C(C)c2csc(-c3ccc(C(C)(C)C)cc3)c2O)ccc1C(=O)O,,CC(C)O,,Cl,[Na+].[OH-],test
US20140094448A1,CSc1nc2c(C=O)cnn2c(NC2CC2)c1C#N.O=C1CNC(=O)N1>>CSc1nc2c(C=C3NC(=O)NC3=O)cnn2c(NC2CC2)c1C#N,,CCO,O,C1CCNCC1,,test
US20020035110A1,CC(C)C(C)(C)C(O[SiH](C)C)[C@H]1CN(C(=O)OC(C)(C)C)S(=O)(=O)O1.CCOC(=O)c1cc2ccc(C(F)(F)F)cc2[nH]1>>CC(C)C(C)(C)C(O[SiH](C)C)[C@@H]1CNC(=O)c2cc3ccc(C(F)(F)F)cc3n21,,CN(C)C=O,ClCCl,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US05864039,O=C(Cl)CCCCCBr.c1ccccc1>>O=C(CCCCCBr)c1ccccc1,,ClCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20100249101A1,CC(=O)c1ccc(F)c(B(O)O)c1.Clc1ccc(Br)s1>>CC(=O)c1ccc(F)c(-c2ccc(Cl)s2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,O,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US04666916,CCCI.c1ccc2c(c1)OC[C@@H]1CCNC[C@H]21>>CCCN1CC[C@H]2COc3ccccc3[C@H]2C1,,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US20160009688A1,Cc1ccc(C(=O)O)cc1N.c1cn(-c2ccc(C3CCNCC3)cc2)cn1>>Cc1ccc(C(=O)N2CCC(c3ccc(-n4ccnc4)cc3)CC2)cc1N,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04731358,CSc1cc2c(cn1)[nH]c1ccc([N+](=O)[O-])cc12>>CSc1cc2c(cn1)[nH]c1ccc(N)cc12,[Pd],C1CCOC1,,CCO,,test
US04368328,COC(=O)Nc1nc2cc(S(=O)(=O)Cl)ccc2[nH]1.COC(=O)Nc1nc2cc(S)ccc2[nH]1>>CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1,[Fe],,,Cl,Cl,test
US20140200227A1,C[Mg]Br.O=Cc1cc(F)cc(F)c1>>CC(O)c1cc(F)cc(F)c1,,C1CCOC1,,,,test
US20120165343A1,CCOC(=O)CCNC(=O)c1ccc(N[C@@H](CC(C)C)c2ccc(-c3ccc(C(F)(F)F)cn3)cc2)nc1>>CC(C)C[C@H](Nc1ccc(C(=O)NCCC(=O)O)cn1)c1ccc(-c2ccc(C(F)(F)F)cn2)cc1,,CO,,C1CCOC1,[Li+].[OH-],test
US04130561,BrCCCCBr.Cc1cc(OC23CC4CC(CC(C4)C2)C3)cc(C)c1N>>Cc1cc(OC23CC4CC(CC(C4)C2)C3)cc(C)c1N1CCCC1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20100075942A1,CN(C)CCO.Nc1ccccc1NC(=O)c1ccc(-c2ncc(O)cc2Cl)cc1>>CN(C)CCOc1cnc(-c2ccc(C(=O)Nc3ccccc3N)cc2)c(Cl)c1,,CN(C)C=O,ClCCl,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080253988A1,CCOC(=O)c1cc(C=O)[nH]c1C.NN>>CCOC(=O)c1cc(C=NN)[nH]c1C,,CCO,,,,test
US20110152240A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(Cl)nc2ccnn12>>CC(C)(C)OC(=O)Nc1cc(Cl)nc2ccnn12,CN(C)c1ccncc1,ClCCl,ClCCl,CCN(CC)CC,,test
US20030069273A1,NNc1ccc(F)cc1F.O=c1nc(-c2ccccc2O)oc2ccccc12>>Oc1ccccc1-c1nc(-c2ccccc2O)n(-c2ccc(F)cc2F)n1,,CCO,,CCN(CC)CC,Cl,test
US06740650B2,C1CCOC1.CCOC(C)=O.COc1cc([N+](=O)[O-])c([Sn](C)(C)C)cc1OC.c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>COc1cc(-c2ccc3cc(OC)c(OC)cc3c2)c([N+](=O)[O-])cc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,,,test
US03952017,CN(C)CCCC1(O)c2ccccc2CCc2c(C3(C)OCCO3)cccc21>>CC(=O)c1cccc2c1CCc1ccccc1C2=CCCN(C)C,,CCO,,Cl,,test
US20120214803A1,Cc1ccc(S(=O)(=O)O)c([N+](=O)[O-])c1.O=S(Cl)Cl>>Cc1ccc(S(=O)(=O)Cl)c([N+](=O)[O-])c1,,CN(C)C=O,,,,test
US20090143355A1,COC(=O)C(c1ccc([N+](=O)[O-])cc1[N+](=O)[O-])(C(F)(F)F)C(F)(F)F>>Nc1ccc2c(c1)N(O)C(=O)C2(C(F)(F)F)C(F)(F)F,[Pd],CCO,,,,test
US20140128390A1,Clc1ncnc2cc(Br)sc12.O=C(NCc1ccc(F)cc1)N1CCNCC1>>O=C(NCc1ccc(F)cc1)N1CCN(c2ncnc3cc(Br)sc23)CC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20020169192A1,CC(C)(C)OC(=O)C(C)(C)Br.Sc1cccc(Br)c1>>CC(C)(C)OC(=O)C(C)(C)Sc1cccc(Br)c1,,CCO,,[K+].[OH-],,test
US20150266867A1,CC(C)(C)OC(=O)NCCCNC(=N)NCc1cnn(C[C@@H]2[C@H](NC(=O)/C(=N\OC3(C(=O)O)CC3)c3csc(N)n3)C(=O)N2S(=O)(=O)O)n1>>N=C(NCCCN)NCc1cnn(C[C@@H]2[C@H](NC(=O)/C(=N\OC3(C(=O)O)CC3)c3csc(N)n3)C(=O)N2S(=O)(=O)O)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090214675A1,CC(N)=CC(=O)CCC(C)C.CC([O-])=CC#N.Cc1cc(=O)c2c(F)ccc(C=O)c2o1>>CC1=C(C#N)C(c2ccc(F)c3c(=O)cc(C)oc23)C(C(=O)CCC(C)C)=C(C)N1,,CC(C)O,,CC(=O)O,,test
US04945098,C=C(COC(=O)CCCCCBr)COC(=O)NCCCCCCCCCCCCCCCCCC.c1ccnnc1>>C=C(COC(=O)CCCCC[n+]1ccccn1)COC(=O)NCCCCCCCCCCCCCCCCCC.[Br-],,Cc1ccccc1,,,,test
US20020143037A1,C1CCOC1.CS(C)=O.O.O=CC=CC=Cc1ccccc1>>O=C(O)CC=CC=CC=Cc1ccccc1,,CS(C)=O,,[H-].[Na+],,test
US20090275570A1,CC(C)(C)OC(=O)N1CCC[C@H](Nc2ncc(C#N)c3cc(Br)sc23)C1.OB(O)c1cccc(F)c1>>CC(C)(C)OC(=O)N1CCC[C@H](Nc2ncc(C#N)c3cc(-c4cccc(F)c4)sc23)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120088748A1,COCC1CN(C(=O)OC(C)(C)C)CCOC1c1ccc(Cl)c(Cl)c1.Cl>>COCC1CNCCOC1c1ccc(Cl)c(Cl)c1.Cl,,CCOC(C)=O,,,,test
US20090221655A1,COC(=O)[C@H]1CN(c2ccc3c(C)noc3c2)C(=O)O1.N>>Cc1noc2cc(N3C[C@H](C(N)=O)OC3=O)ccc12,,CO,,CC#N,,test
US20090312310A1,CC(C)C1=C(C(=O)N(CCN(C)C(=O)C(F)(F)F)C(C)C)SC2=N[C@@](C)(c3ccc(Cl)cc3)[C@@H](c3ccc(Cl)cc3)N21>>CNCCN(C(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)cc3)[C@H]2c2ccc(Cl)cc2)S1)C(C)C,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US04082735,CC(=O)N[C@@H]1[C@@H](OCC(=O)N[C@@H](C)C(=O)N[C@H](CCC(=O)OCc2ccccc2)C(N)=O)[C@H](O)[C@@H](CO)O[C@@]1(O)Cc1ccccc1.CC(=O)OC(C)=O>>CC(=O)N[C@@H]1[C@@H](OCC(=O)N[C@@H](C)C(=O)N[C@H](CCC(=O)OCc2ccccc2)C(N)=O)[C@H](O)[C@@H](COC(C)=O)O[C@@]1(O)Cc1ccccc1,,c1ccncc1,,CO,,test
US20080300232A1,CC(C)(C)OC(=O)N1CCC(NC(=O)COc2ccc(F)c(F)c2)C1>>O=C(COc1ccc(F)c(F)c1)NC1CCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110082133A1,COC(=O)c1ccc(CCn2c(C)c(Cl)cc(Cl)c2=O)cc1>>Cc1c(Cl)cc(Cl)c(=O)n1CCc1ccc(C(=O)O)cc1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20100056508A1,O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(OCc1ccccc1)N(CCc1ccc(O)c2[nH]c(=O)ccc12)CCN(C(=O)CCNCCc1cccc(Br)c1)C1CCCCCC1.OB(O)c1ccccc1>>O=C(CCNCCc1cccc(-c2ccccc2)c1)N(CCNCCc1ccc(O)c2[nH]c(=O)ccc12)C1CCCCCC1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[K+].[K+],,test
US06939845B2,Cc1ccccc1.O=C(CO)c1ccccc1.c1ccncc1>>CC=CCCC1CCC=CO1,c1ccncc1,,,O=C([O-])O.[Na+],,test
US05852011,COC(=O)COc1ccc(N(CCCl)CCCl)cc1>>O=C(O)COc1ccc(N(CCCl)CCCl)cc1,,Cl,,,,test
US05719141,CC(C)(C)[Si](C)(C)Cl.OCC1Cc2ccccc2N(Cc2ccccc2)C1>>CC(C)(C)[Si](C)(C)OCC1Cc2ccccc2N(Cc2ccccc2)C1,,ClCCl,,c1c[nH]cn1,,test
US20070287708A1,CN1CCNCC1.Cc1c(Nc2c(C#N)cncc2-c2cc3cc(C=O)ccc3o2)cc(Cl)c2[nH]ccc12>>Cc1c(Nc2c(C#N)cncc2-c2cc3cc(CN4CCN(C)CC4)ccc3o2)cc(Cl)c2[nH]ccc12,,C1CCOC1,CCO,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20030186987A1,CO.Fc1cc2c(Nc3cccc(Br)c3)ncnc2cn1>>COc1cc2c(Nc3cccc(Br)c3)ncnc2cn1,,CO,,C[O-].[Na+],,test
US08946261B2,CI.O=C(Nc1ccccc1F)Oc1ccc2c(c1)NCCC2>>CN1CCCc2ccc(OC(=O)Nc3ccccc3F)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20150152108A1,NCc1cn(-c2cccc(NC(=O)N3c4nc(-c5cccc(C(F)(F)F)c5)ccc4N4CC[C@H]3C4)c2)nn1.O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)NCCCCCC(=O)ON1C(=O)CCC1=O>>O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)NCCCCCC(=O)NCc1cn(-c2cccc(NC(=O)N3c4nc(-c5cccc(C(F)(F)F)c5)ccc4N4CC[C@H]3C4)c2)nn1,,CC#N,,CCN(CC)CC,CN(C)C=O,test
US20150252030A1,COC(=O)CBr.Oc1cccnc1N1CCCC1>>COC(=O)COc1cccnc1N1CCCC1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080171754A1,Brc1ccccn1.CCOC(=O)c1ccc([Zn]Br)o1>>CCOC(=O)c1ccc(-c2ccccn2)o1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,,,test
US05808146,CC(O)COCc1ccccc1>>CC(=O)COCc1ccccc1,,CN(C)C=O,O,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20110230452A1,C#C[Si](C)(C)C.O=C(O)[C@@H](Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc(Br)s1>>C[Si](C)(C)C#Cc1ccc(S(=O)(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)O)s1,[Cu]I,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,,test
US04652556,CO.CSCCS(=O)(=O)NC(C)(C)C#N>>CS(=O)CCS(=O)(=O)NC(C)(C)C#N,,CO,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20040077551A1,CC(C)c1csc(C(=O)O)n1.COc1ccc(C(=O)c2ccccc2)c(N)c1>>COc1ccc(C(C)=O)c(NC(=O)c2nc(C)cs2)c1,,c1ccncc1,,O=P(Cl)(Cl)Cl,,test
US04182711,COCCOCC(=O)SC1CC(=O)N1C(Cl)C(=O)OCc1ccc([N+](=O)[O-])cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>COCCOCC(=O)SC1CC(=O)N1C(C(=O)OCc1ccc([N+](=O)[O-])cc1)=P(c1ccccc1)(c1ccccc1)c1ccccc1,,C1CCOC1,,Cc1cccc(C)n1,,test
US20100105906A1,O=C(c1cc(F)cnc1Oc1cc(Cl)ccc1Cl)N1CCNc2ccccc21.O=C1CCC1>>O=C(c1cc(F)cnc1Oc1cc(Cl)ccc1Cl)N1CCN(C2CCC2)c2ccccc21,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20100222318A1,CN(C)C(=O)c1ccc(B(O)O)cc1.COC(=O)c1nc(Br)cnc1N>>CN(C)C(=O)c1ccc(-c2cnc(N)c(C(=O)O)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090227601A1,Cc1ccc(S(=O)(=O)N[C@H](CC(=O)OC(C)(C)C)C(=O)NC(C)CO)cc1>>Cc1ccc(S(=O)(=O)N[C@H](CC(=O)OC(C)(C)C)C(=O)NC(C)C=O)cc1,,ClCCl,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20150322073A1,CC(C)N1C(=O)C(C)(C)c2cc([N+](=O)[O-])c(F)cc21.C[C@H](N)c1ccccc1>>CC(C)N1C(=O)C(C)(C)c2cc([N+](=O)[O-])c(N[C@@H](C)c3ccccc3)cc21,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,O,test
US05834493,COc1ccc2[nH]cc(CC3=CCCNC3)c2c1.Fc1ccc(CCCCCl)cc1>>COc1ccc2[nH]cc(CC3=CCCN(CCCCc4ccc(F)cc4)C3)c2c1,,CN(C)C=O,,[I-].[K+],,test
US20150133400A1,CC1(C)OB(c2cnn(CC(F)(F)F)c2)OC1(C)C.FC1(F)CCC(Cn2cc(I)c3ncc(Br)cc32)CC1>>FC(F)(F)Cn1cc(-c2cn(CC3CCC(F)(F)CC3)c3cc(Br)cnc23)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20110098304A1,CN1CCN(c2ccc(-c3n[nH]c(=O)c4ccccc34)cc2N)CC1.CN=C=O>>CNC(=O)Nc1cc(-c2n[nH]c(=O)c3ccccc23)ccc1N1CCN(C)CC1,,c1ccncc1,,,,test
US04849441,CCN(CC)CCN1C(=O)c2ccccc2C1c1ccccc1C(=O)O.CO>>CCN(CC)CCN1C(=O)c2ccccc2C1c1ccccc1C(=O)OC,,CO,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US20150225381A1,CC(C)(C)OC(=O)NC1(CO)CC1.CC1(C)C(=O)N(c2ccc(C#N)c(Cl)c2)C(=S)N1c1ccc(O)c(F)c1>>CC(C)(C)OC(=O)NC1(COc2ccc(N3C(=S)N(c4ccc(C#N)c(Cl)c4)C(=O)C3(C)C)cc2F)CC1,,Cc1ccccc1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20060166997A1,COC(=O)[C@H]1CCN(C(=O)OC(C)(C)C)[C@H]1c1ccccc1SC(C)C.O=S([O-])OO>>COC(=O)[C@H]1CCN(C(=O)OC(C)(C)C)[C@H]1c1ccccc1S(=O)(=O)C(C)C,,CO,,O,,test
US05917054,N#Cc1ccc(NN)cc1.O=C(OC1CCCCC1)c1ccccc1>>N#Cc1ccc2[nH]c3c(c2c1)CC(OC(=O)c1ccccc1)CC3,,CC(=O)O,,Cl,,test
US20060241172A1,COc1cccc(B(O)O)c1OC.Clc1cccc(Cl)c1Br>>COc1cccc(-c2c(Cl)cccc2Cl)c1OC,,COCCOC,O,[Na+].[OH-],,test
US20020040146A1,CS(=O)(=O)N1C[C@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)C[C@H]1C(=O)O.C[Si](C)(C)C=[N+]=[N-]>>CS(=O)(=O)N1C[C@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)C[C@H]1C(=O)C=[N+]=[N-],CN(C)C=O,CCCCCC,ClCCl,O=C(Cl)C(=O)Cl,,test
US04950666,C=CCCCCCCCCC=C(F)F.OO>>OCCCCCCCCCCC=C(F)F,,ClCCl,,O,[Na+].[OH-],test
US20110160212A1,Fc1ccc(Cl)c(CN=C=S)c1.NN>>NNC(=S)NCc1cc(F)ccc1Cl,,C1COCCO1,,O,,test
US20070287737A1,CCOC(=O)C(=N)NO.O=C(O)c1ccncc1Nc1ccc(I)cc1F>>CCOC(=O)c1noc(-c2ccncc2Nc2ccc(I)cc2F)n1,,CN(C)C=O,O,O=C(n1ccnc1)n1ccnc1,,test
US20150264927A1,CC(C)c1ccccc1C=O.NC1CC1>>CC(C)c1ccccc1CNC1CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20090275571A1,CN(C)C=O.CNC(CN1CCOCC1)c1ccc(-c2ccccc2)cc1.O=C(O)CN1CCOc2cc(Cl)c(Cl)cc21>>CN(C(=O)CN1C(=O)COc2cc(Cl)c(Cl)cc21)C(CN1CCOCC1)c1ccc(-c2ccccc2)cc1,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US04075341,CCI.Oc1cccc(-c2nc3n(n2)CCc2ccccc2-3)c1>>CCOc1cccc(-c2nc3n(n2)CCc2ccccc2-3)c1,,CCO,,C,C[O-].[Na+],test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCc1ccccc1.Cc1c[nH]c2ccc(O)cc12>>COc1cc2c(Oc3ccc4[nH]cc(C)c4c3)ncnc2cc1OCc1ccccc1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20070253896A1,Cc1cccnc1Cl.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1Cc1ccccn1,,CN(C)C=O,O,[I-].[Na+],O=C([O-])[O-].[Cs+].[Cs+],test
US20080262042A1,O=C1CCC(=O)N1Cl.O=Cc1c[nH]c(-c2cccnc2F)c1>>O=Cc1c[nH]c(-c2cccnc2F)c1Cl,,CN(C)C=O,,O,,test
US05646000,COC(=O)[C@H](CNC(=O)OC(C)(C)C)NS(=O)(=O)c1cccc2c(N(C)C)cccc12>>COC(=O)[C@H](CN)NS(=O)(=O)c1cccc2c(N(C)C)cccc12,,CCOC(C)=O,,,,test
US20090299072A1,BrCCCBr.CCOC(=O)Cc1ccc([N+](=O)[O-])c(OCC(F)(F)F)c1>>CCOC(=O)C1(c2ccc([N+](=O)[O-])c(OCC(F)(F)F)c2)CCC1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20150141413A1,C[C@@]1(c2cc([N+](=O)[O-])ccc2F)CS(=O)(=O)CC(N)=N1>>C[C@@]1(c2cc(N)ccc2F)CS(=O)(=O)CC(N)=N1,[Pd],CCO,,CCN(CC)CC,,test
US20070135631A1,CS(=O)(=O)Cl.NCc1cc([C@@](Cc2ccccc2)(NC(=O)c2ccc(F)c(C(F)(F)F)c2)c2cc(F)cc(OC(F)(F)C(F)F)c2)ccc1F>>CS(=O)(=O)NCc1cc([C@@](Cc2ccccc2)(NC(=O)c2ccc(F)c(C(F)(F)F)c2)c2cc(F)cc(OC(F)(F)C(F)F)c2)ccc1F,,ClCCl,,Cl,Cl,test
US20160229814A1,CCN1C(=O)C(c2ccccc2)Oc2cc([N+](=O)[O-])ccc21>>CCN1C(=O)C(c2ccccc2)Oc2cc(N)ccc21,[Pd],CO,,[H][H],,test
US20150150766A1,CN1CCN(c2cc(N)ccc2[N+](=O)[O-])CC1.COS(=O)(=O)OC>>COS(=O)(=O)[O-].C[N+]1(C)CCN(c2cc(N)ccc2[N+](=O)[O-])CC1,,C1CCOC1,,,,test
US20090209532A1,CCOc1cc(C=O)c([N+](=O)[O-])cc1OCc1ccccc1>>CCOc1cc(C=O)c([N+](=O)[O-])cc1O,,CC(=O)O,,Cl,,test
US20090099248A1,CCOC(=O)c1cc2c([nH]1)CCC2.O>>CCOC(=O)c1cc2c([nH]1)C(=O)CC2,,C1CCOC1,,,,test
US20100010053A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c(CC=O)cn(C)c34)no2)cc1Cl.O=C(O)[C@@H]1CCCN1>>CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCN5CCC[C@H]5C(=O)O)cn(C)c34)no2)cc1Cl,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04654335,COC(=O)C(=Cc1ccccc1C(F)(F)F)C(C)=O.Nc1ccccc1S>>COC(=O)C1=C(C)Nc2ccccc2SC1c1ccccc1C(F)(F)F,,CCOC(C)=O,CN(C)C=O,,,test
US04962234,CC(=O)c1ccccc1.Nc1ccccc1Cl>>CC(=Nc1ccccc1Cl)c1ccccc1,,O,,c1ccccc1,,test
US05091419,CC(=O)Oc1ccc(NC(=O)N(Cc2cccc(CN(C(=O)Nc3ccc(OC(C)=O)cc3)C3CCCCCC3)c2)C2CCCCCC2)cc1>>O=C(Nc1ccc(O)cc1)N(Cc1cccc(CN(C(=O)Nc2ccc(O)cc2)C2CCCCCC2)c1)C1CCCCCC1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20020151088A1,CC(C)(C)[C@H](N)C(=O)C(CCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)C(=O)O>>NCC(=O)C(CCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US06046195,C=C1CO[C@]2(CCCN(C(=O)OC(C)(C)C)[C@H]2c2ccccc2)C1.CO>>CC(C)(C)OC(=O)N1CCC[C@@]2(CC(=O)CO2)[C@@H]1c1ccccc1,,ClCCl,,,,test
US20030055047A1,CN(Cc1cccnc1)C(=O)OC(C)(C)C.O=C(OO)c1cccc(Cl)c1>>CN(Cc1ccc[n+]([O-])c1)C(=O)OC(C)(C)C,,ClCCl,,,,test
US20140336388A1,CI.O=c1[nH]nc(C2CCN(c3ccc([N+](=O)[O-])cc3)CC2)o1>>Cn1nc(C2CCN(c3ccc([N+](=O)[O-])cc3)CC2)oc1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120101127A1,CC(C)S(=O)(=O)Cl.CC1(C)CC(c2ccccc2N)Nc2ccc(C#N)cc21>>CC(C)S(=O)(=O)Nc1ccccc1C1CC(C)(C)c2cc(C#N)ccc2N1,,O,c1ccncc1,,,test
US20010027196A1,CI.N#Cc1c(-c2ccco2)cc(N)[nH]c1=S>>CSc1nc(N)cc(-c2ccco2)c1C#N,,CO,,C[O-].[Na+],,test
US20090215728A1,COC(OC)N(C)C.Nc1ccc([N+](=O)[O-])cc1F>>CN(C)C=Nc1ccc([N+](=O)[O-])cc1F,,CN(C)C=O,,O,,test
US20030069239A1,COc1ccc(N)cc1.Cc1cc(Cl)nc(-c2ccccn2)n1>>COc1ccc(Nc2cc(C)nc(-c3ccccn3)n2)cc1,,O,,Cl,[Na+].[OH-],test
US20030232808A1,CC(C)(C)OC(=O)NCc1ccc2c(c1)CCC(CO[Si](C)(C)C(C)(C)C)C2>>CC(C)(C)OC(=O)NCc1ccc2c(c1)CCC(CO)C2,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090137549A1,CC(C)(C)OC(=O)NN.O=C1CN(C(c2ccccc2)c2ccccc2)C1>>CC(C)(C)OC(=O)NN=C1CN(C(c2ccccc2)c2ccccc2)C1,,CO,,CC(=O)O,,test
US20160009697A1,COc1ccc(-c2cc(C=C3CCOCC3)nc(N3CCNC(C)(C)C3)c2)cc1>>COc1ccc(-c2cc(CC3CCOCC3)nc(N3CCNC(C)(C)C3)c2)cc1,[Pd],CO,,,,test
US20040048897A1,CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2c(Cl)ccc(N)c2O)CC1.O=c1c(Cl)c(Cl)c1=O>>CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2c(Cl)ccc(Nc3c(Cl)c(=O)c3=O)c2O)CC1,,C1CCOC1,,,,test
US04472412,BrBr.CCCCC(C)(C)c1ccc(CC(C)CCl)cc1>>CCCCC(C)(C)c1ccc(CC(C)CCl)c(Br)c1,[Fe],ClCCl,,,,test
US20160222005A1,CC(C)(C)OC(=O)N1CCN(c2ccc3nc(-c4ccc(SCc5ccccc5)cc4)[nH]c3n2)CC1>>c1ccc(CSc2ccc(-c3nc4ccc(N5CCNCC5)nc4[nH]3)cc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04477447,CCOCC(COCC)OC(=O)C1=CCS[C@@H]2C(NC(=O)C(=NOC)c3csc(NC=O)n3)C(=O)N12>>CCOCC(COCC)OC(=O)C1=CCS[C@@H]2C(NC(=O)C(=NOC)c3csc(N)n3)C(=O)N12,,CO,,Cl,O=C([O-])O.[Na+],test
US04383945,COC(C[C@H]1NC(=O)[C@@H]1N1C(=O)c2ccccc2C1=O)OC>>O=CC[C@H]1NC(=O)[C@@H]1N1C(=O)c2ccccc2C1=O,,CC(=O)O,,,,test
US20160031838A1,CC(=O)c1cccc(N)c1O.O=C(Cl)CCl>>CC(=O)c1cccc2c1OCC(=O)N2,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],O=C([O-])O.[Na+],test
US06034087,CC(C)(C)[Si](C)(C)OCC(COCc1ccccc1)OS(C)(=O)=O.CCOC(=O)CS>>CCOC(=O)CSOC(COCc1ccccc1)CO[Si](C)(C)C(C)(C)C,,CN(C)C=O,,C,C[O-].[Na+],test
US04156791,COC(=O)C(F)(F)C(F)(F)C(F)(F)F.O>>COC(=O)C(F)(F)C(F)(F)C(F)(F)F.O,,O,,,,test
US20060166997A1,Cc1ccc(F)cc1F.O=C1CCC(=O)N1I>>Cc1cc(I)c(F)cc1F,,O=C(O)C(F)(F)F,,,,test
US05281747,CC#N.CC(=O)O.CCO[PH](=O)C(F)F>>CCOP(=O)(CCC#N)C(F)F,,CCO,,[Na],,test
US20030004150A1,CCCCC=O.CC[C@@]1(O)CC(=O)OCc2c1cc1n(c2=O)Cc2cc3cc(F)c(F)cc3nc2-1>>CCCCc1c2c(nc3cc(F)c(F)cc13)-c1cc3c(c(=O)n1C2)COC(=O)C[C@]3(O)CC,,O,O=S(=O)(O)O,OO,,test
US20010051619A1,CN1CC(CO)Oc2ccccc21.CS(=O)(=O)Cl>>CN1CC(COS(C)(=O)=O)Oc2ccccc21,,ClCCl,,CCN(CC)CC,O,test
US20130281451A1,CC1(C)OC(=O)CC(=O)O1.COC(OC)N(C)C.O=C(Cl)Cc1ccccc1>>O=C(O)c1c[nH]cc(-c2ccccc2)c1=O,,ClCCl,,CO,,test
US05284971,CCOC(=O)Cc1cc(Br)c(SC(=O)N(C)C)c(Br)c1>>COC(=O)Cc1cc(Br)c(S)c(Br)c1,,[Na+],[OH-],CCO,,test
US20140343032A1,COC(=O)C1=C(CBr)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl.O=C(O)C12CCC(COC1)N2>>COC(=O)C1=C(CN2[C@@H]3CC[C@@]2(C(=O)O)COC3)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US07390838B2,OC1CCCC1.Oc1cccc(O)c1>>Oc1ccc(C2CCCC2)c(O)c1,,CCOC(C)=O,O,O=P(O)(O)O,,test
US20120010247A1,CC(O)c1cc2cc(Br)ccc2o1.[N-]=[N+]=[N-]>>CC(N=[N+]=[N-])c1cc2cc(Br)ccc2o1,,CN(C)C=O,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20050171358A1,CN(C(=O)Cl)c1ccccc1.NCc1cc(-c2ccccc2)no1>>CN(C(=O)NCc1cc(-c2ccccc2)no1)c1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20060069110A1,CN(c1ccnc(S(C)=O)n1)c1nccc(C(C)(C)C)n1.NCCc1ccccc1>>CN(c1ccnc(NCCc2ccccc2)n1)c1nccc(C(C)(C)C)n1,,CS(C)=O,,,,test
US20110021521A1,CS(=O)(=O)Nc1ccc(B(O)O)cc1.Clc1ccc(Cl)nn1>>CS(=O)(=O)Nc1ccc(-c2ccc(Cl)nn2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US05284853,C#Cc1ccc2[nH]c(CCCC)nc(=O)c2c1.CC(=O)O>>CCCCc1nc(=O)c2cc(C(C)=O)ccc2[nH]1,,CC(=O)O,,O,O=S(=O)(O)O,test
US20090221555A1,COc1cc2c(cc1[N+](=O)[O-])CCNCC2.O=S(=O)(OCC(F)(F)F)C(Cl)(Cl)Cl>>COc1cc2c(cc1[N+](=O)[O-])CCN(CC(F)(F)F)CC2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060189639A1,CN(C)c1ccnc2sc3c(=O)n(-c4cccc(C(=N)NO)c4)cnc3c12.O=C(Cl)c1ccccc1>>CN(C)c1ccnc2sc3c(=O)n(-c4cccc(-c5noc(-c6ccccc6)n5)c4)cnc3c12,,c1ccncc1,,O=C([O-])[O-].[K+].[K+],,test
US20080090855A1,FC(F)(F)Oc1ccc(CBr)cc1.O=c1[nH]c2ccccc2[nH]1>>O=c1[nH]c2ccccc2n1Cc1ccc(OC(F)(F)F)cc1,,CN(C)C=O,O,Cl,[I-].[K+],test
US06174839B1,CCOC(=O)Cl.CCOc1cc(N)c(F)cc1Br>>CCOC(=O)Nc1cc(OCC)c(Br)cc1F,,ClCCl,,c1ccncc1,,test
US20120145959A1,C1CCNC1.O=C1CCC(C2CCC3(CC2)OCCO3)CC1>>C1=C(N2CCCC2)CCC(C2CCC3(CC2)OCCO3)C1,,O,,Cc1ccccc1,,test
US20130165440A1,FC(F)(F)c1cc(Nc2nnc(Cl)c3ccccc23)cc(C(F)(F)F)c1.c1cc2c(cn1)CNC2>>FC(F)(F)c1cc(Nc2nnc(N3Cc4ccncc4C3)c3ccccc23)cc(C(F)(F)F)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100273819A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C(C)(C)Oc1cc(F)c(Cl)cc1/C=C1\C(=O)Nc2cc(Cl)ccc21>>COC(=O)C(C)(C)Oc1cc(F)c(Cl)cc1/C=C1\C(=O)N(C(=O)OC(C)(C)C)c2cc(Cl)ccc21,CN(C)c1ccncc1,ClCCl,,,,test
US20070265225A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1COC[C@@H](c2cc(F)cc(F)c2)N1>>CC(C)(C)OC(=O)N1C(=O)COC[C@H]1c1cc(F)cc(F)c1,CN(C)c1ccncc1,ClCCl,,,,test
US20130287730A1,COC(=O)N[C@H](C(=O)N1C[C@@H](C)C[C@H]1c1nc(-c2ccc(Br)cc2)c[nH]1)C(C)C.O=C1CCC(=O)N1Cl>>COC(=O)N[C@H](C(=O)N1C[C@@H](C)C[C@H]1c1nc(-c2ccc(Br)cc2)c(Cl)[nH]1)C(C)C,,CC#N,,,,test
US20110071129A1,CCO/N=C(\c1ccc(F)c(F)c1)c1ccc(CO)cn1.CS(=O)(=O)Cl>>CCO/N=C(\c1ccc(F)c(F)c1)c1ccc(COS(C)(=O)=O)cn1,,CCN(CC)CC,,CCOC(C)=O,,test
US20120225904A1,Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccn2c(=O)[nH]nc2c1.Clc1ccccc1I>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccn2c(=O)n(-c3ccccc3Cl)nc2c1,[Cu]I,CS(C)=O,,CN[C@@H]1CCCC[C@H]1NC,O=C([O-])[O-].[K+].[K+],test
US20090156603A1,COC(=O)CCC(=O)CBr.NC(=S)Nc1ncc(Br)cc1Oc1ccccc1>>COC(=O)CCc1csc(Nc2ncc(Br)cc2Oc2ccccc2)n1,,CCO,,CCN(CC)CC,,test
US20120088764A1,CC(C)(C)[Si](C)(C)Cl.OCCOc1cccc(Br)c1>>CC(C)(C)[Si](C)(C)OCCOc1cccc(Br)c1,,ClCCl,,c1c[nH]cn1,,test
US20120101100A1,CN1CCNCC1.Nc1cc(Cl)nc(Cl)c1>>CN1CCN(c2cc(N)cc(Cl)n2)CC1,,O,,C1COCCO1,,test
US20100273786A1,COC(=O)c1nc(C(F)(F)F)n2c1CN(C(=O)OC(C)(C)C)CC2>>CC(C)(C)OC(=O)N1CCn2c(C(F)(F)F)nc(C(=O)O)c2C1,,CO,,Cl,[Na+].[OH-],test
US20150274703A1,COC(=O)c1cn[nH]c1C.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1C(=O)O,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20160108039A1,CC(Cl)C(=O)Cl.NC(CO)C1CC(OCc2ccccc2)C1>>CC(Cl)C(=O)NC(CO)C1CC(OCc2ccccc2)C1,,CC(C)O,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20140329799A1,CSc1nc(N[C@@H]2C[C@H](CO)[C@H]3OC(C)(C)O[C@@H]23)c(-c2nc3ccccc3s2)c(=O)[nH]1>>CSc1nc(N[C@@H]2C[C@H](CO)[C@@H](O)[C@H]2O)c(-c2nc3ccccc3s2)c(=O)[nH]1,,CO,,Cl,,test
US06136823,CN.Nc1nc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Cl)c32)c(F)cc1F>>CNc1c(F)cc2c(=O)c(C(=O)O)cn(-c3nc(N)c(F)cc3F)c2c1Cl,,c1ccncc1,,,,test
US20020055631A1,COC(=O)c1ccc(-c2ccc(Cl)nc2)cc1>>O=C(O)c1ccc(-c2ccc(Cl)nc2)cc1,,C1CCOC1,O,[Li]O,,test
US20150099777A1,CCOc1cc(C=O)cc(C2CC2)c1O.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOc1cc(C=O)cc(C2CC2)c1OS(=O)(=O)C(F)(F)F,CN(C)c1ccncc1,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US20150232483A1,Br.BrBr.CC(=O)c1cccnc1>>Br.O=C(CBr)c1cccnc1,,CC(=O)O,CCOCC,,,test
US20110105461A1,C1CCNCC1.Cc1ccc(S(=O)(=O)OC[C@@H]2COc3ccc(S(C)(=O)=O)cc3O2)cc1>>CS(=O)(=O)c1ccc2c(c1)O[C@H](CN1CCCCC1)CO2,,CC#N,,,,test
US20090099185A1,Nc1c(C(=O)c2ccc(F)cc2)ccc(=O)n1-c1c(F)cc(OC2CCC3(CC2)OCCO3)cc1F>>Nc1c(C(=O)c2ccc(F)cc2)ccc(=O)n1-c1c(F)cc(OC2CCC(=O)CC2)cc1F,,C1COCCO1,O,Cl,,test
US20140094512A1,CCOC(=O)c1ccc(N)cc1.Cc1ccc(C2=CC(C)(C)Oc3c(Br)cc(C(=O)O)cc32)cc1>>CCOC(=O)c1ccc(NC(=O)c2cc(Br)c3c(c2)C(c2ccc(C)cc2)=CC(C)(C)O3)cc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20050096256A1,CN(C)C=O.COCCl.O=Cc1cc(O)cc(O)c1>>COCOc1cc(C=O)cc(OCOC)c1,,CN(C)C=O,,CCOCC,[H-].[Na+],test
US20080181866A1,C[C@@H]1NC(C(=O)O)CS1.O=C(Cl)OCc1ccccc1>>C[C@H]1SCC(C(=O)O)N1C(=O)OCc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05246931,C=C1CC(C(=O)O)C1.OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>C=C1CC(N)(C(=O)OCc2ccccc2)C1,,CCOCC,Cc1ccccc1,CCN(CC)CC,,test
US20130289238A1,COc1cc(O)c2cc(-c3cn4nc(OC)sc4n3)oc2c1.OCc1nsc(-c2ccccc2)n1>>COc1cc(OCc2nsc(-c3ccccc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1,,C1CCOC1,CCOC(C)=O,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US05153352,CC(C)(C)[Si](OCC1CC(N=[N+]=[N-])C1O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](OCC1CC(N)C1O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)(c1ccccc1)c1ccccc1,[Pd],CO,,O=C[O-].[NH4+],,test
US20150232460A1,CO.O=C(O)c1ncccc1Br>>COC(=O)c1ncccc1Br,,O=C([O-])O,[Na+],O=S(=O)(O)O,,test
US04410716,CCOCC.O=C(Cl)Cc1ccc(CC(=O)Cl)c(Cc2ccccc2)c1>>O=C(O)Cc1ccc2c(c1)Cc1ccccc1C(=O)C2,,CC(Cl)Cl,,FB(F)F,,test
US20140010783A1,CI.N#CN.S=C=Nc1cc(Cl)c(Cl)c(Cl)c1>>CS/C(=N\C#N)Nc1cc(Cl)c(Cl)c(Cl)c1,,CO,,C[O-].[Na+],,test
US20130331382A1,O=[N+]([O-])c1ccc(F)c(Br)c1.Oc1ccccc1>>O=[N+]([O-])c1ccc(Oc2ccccc2)c(Br)c1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040038987A1,COCOc1cccc2c1C(=O)OC2=O>>COCOc1cccc(CO)c1CO,,C1CCOC1,CCOCC,[Al+3].[H-].[H-].[H-].[H-].[Li+],[Cl-].[NH4+],test
US06416861B1,Brc1ccc(COC2CCCCO2)cn1.C=CC[Si](C)(C)Cl>>C=CCc1ncc(COC2CCCCO2)cc1[SiH](C)C,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20160102071A1,CCOC(=O)CC1(c2ccc(O)cc2)CC(O)C1>>CCOC(=O)CC1(c2ccc(O)cc2)CC(=O)C1,,CS(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20130116249A1,CCOC(=O)c1c[nH]c2ccc(C(=O)c3c(C)c(OC)c4ccccn34)cc2c1=O.CI>>CCOC(=O)c1cn(C)c2ccc(C(=O)c3c(C)c(OC)c4ccccn34)cc2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080167287A1,CC(C)(C)OC(=O)[C@@H](NC(=O)c1ccc(-c2cnc3ncc(Cc4ccc5ncccc5c4)n3n2)cc1F)C(C)(C)C.O=C(O)C(F)(F)F>>CC(C)(C)[C@H](NC(=O)c1ccc(-c2cnc3ncc(Cc4ccc5ncccc5c4)n3n2)cc1F)C(=O)O.O=C(O)C(F)(F)F,,ClCCl,,,,test
US06197978B1,NC(=O)c1ccc(F)c2c1CC([N+](=O)[O-])CO2>>NC(=O)c1ccc(F)c2c1CC(N)CO2,[Ni],C1CCOC1,,CCO,,test
US05866684,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(F)(F)C[C@H](N)C(=O)O>>CC(F)(F)C[C@H](NC(=O)OC(C)(C)C)C(=O)O,,CN(C)C=O,,CCN(CC)CC,Cc1ccc(S(=O)(=O)O)cc1,test
US20090093456A1,COc1cc(N)ccc1O[Si](C(C)C)(C(C)C)C(C)C.Cc1cc(-c2ccc(Cl)cc2)sc1C(=O)O>>COc1cc(NC(=O)c2sc(-c3ccc(Cl)cc3)cc2C)ccc1O[Si](C(C)C)(C(C)C)C(C)C,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20050171087A1,Nc1cc(Cl)ccc1Nc1ccccc1C(=O)O>>O=C1Nc2cc(Cl)ccc2Nc2ccccc21,,Cc1ccccc1C,,,,test
US06046189,COc1ccc(-c2c(Cl)c(CN)nc3sc4c(c23)CCN(Cc2ccccc2)C4)cc1OC.O=C(O)Cn1cncn1>>COc1ccc(-c2c(Cl)c(CNC(=O)Cn3cncn3)nc3sc4c(c23)CCN(Cc2ccccc2)C4)cc1OC,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20120190649A1,CC(C)(C)OC(=O)NCCC(=O)NS(=O)(=O)c1ccccc1>>NCCC(=O)NS(=O)(=O)c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040191879A1,O=C1CC=Cc2ccccc21>>O[C@H]1CCCc2ccccc21,,O,,,,test
US20090186884A1,COC(=O)NCCO[C@@H](c1cccc(Cl)c1)[C@H]1CN(C(=O)OC(C)(C)C)CCO1>>COC(=O)NCCO[C@@H](c1cccc(Cl)c1)[C@H]1CNCCO1,,ClCCl,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],,test
US20120220577A1,O=C(COc1cccc([N+](=O)[O-])c1)N1CCOCC1>>Nc1cccc(OCC(=O)N2CCOCC2)c1,[Pd],,,,,test
US20040043987A1,Cc1ccc(S(N)(=O)=O)c(N)c1.ClI>>Cc1cc(N)c(S(N)(=O)=O)cc1I,,ClC(Cl)Cl,,,,test
US20140275080A1,Cc1nc([N+](=O)[O-])ccc1Oc1ccnc(-c2ccc(C3CCN(C)CC3)cc2)c1>>Cc1nc(N)ccc1Oc1ccnc(-c2ccc(C3CCN(C)CC3)cc2)c1,[Pd],CO,,,,test
US20080312192A1,CN1CCNCC1.O=[N+]([O-])c1ccc(Br)c(C(F)(F)F)c1>>CN1CCN(c2ccc(N)cc2C(F)(F)F)CC1,[Ni],CO,ClCCl,,,test
US20150080369A1,Cc1ccc(N(CC(C)C)S(=O)(=O)c2ccc(OCC3CCOCC3)cc2C(=O)O)c(C)c1>>Cc1ccc(N(CC(C)C)S(=O)(=O)c2ccc(OCC3CCOCC3)cc2CO)c(C)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20160272628A1,CC(C)(C)N1C(CN)c2cc(-c3c[nH]c4cc(F)ccc34)ccc2S1(=O)=O.COC(=O)Cl>>COC(=O)NCC1c2cc(-c3c[nH]c4cc(F)ccc34)ccc2S(=O)(=O)N1C(C)(C)C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US03984398,CCOC(=O)CC(=O)[O-].CNc1ccccc1[N+](=O)[O-]>>CCOC(=O)CC(=O)N(C)c1ccccc1[N+](=O)[O-],,c1ccccc1,,ClP(Cl)(Cl)(Cl)Cl,,test
US20040019033A1,O=C(O)c1cc(Cl)cc(OC(F)(F)F)c1>>OCc1cc(Cl)cc(OC(F)(F)F)c1,,C1CCOC1,,B,,test
US20040110749A1,CCO.FC(F)(F)c1ncnc(Cl)c1Br>>CCOc1ncnc(C(F)(F)F)c1Br,,CCO,,C,C[O-].[Na+],test
US20050250753A1,BrCc1ccccc1Br.CCNCC>>CCN(CC)Cc1ccccc1Br,,Cc1ccccc1,,,,test
US20110166169A1,CC(O)CCN.N#Cc1ccc(-n2c3ccccc3c3c(-c4nc5ccc(F)cc5[nH]4)cccc32)cc1F.OO>>CC(O)CCNc1cc(-n2c3ccccc3c3c(-c4nc5ccc(F)cc5[nH]4)cccc32)ccc1C(N)=O,,CCO,CS(C)=O,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20060128732A1,CCOC(=O)CC(=O)c1cccs1.Nc1ccccc1-c1ncc[nH]1>>O/C(=C\c1nc2ccccc2c2nccn12)c1cccs1,,Cc1ccccc1,,,,test
US05985892,COC(=O)C(C)(C)c1cnc2[nH]c(-c3cc(C)cc(C)c3)c([C@H](C)COCc3ccccc3)c2c1>>Cc1cc(C)cc(-c2[nH]c3ncc(C(C)(C)C(=O)O)cc3c2[C@H](C)COCc2ccccc2)c1,,CO,,Cl,[K+].[OH-],test
US20090264498A1,CC(C)(C)OC(=O)N1CC[C@@H](NS(=O)(=O)c2cc(Br)ccc2Br)C1.CC(C)CBr>>CC(C)CN([C@@H]1CCN(C(=O)OC(C)(C)C)C1)S(=O)(=O)c1cc(Br)ccc1Br,,CN(C)C=O,,[H-].[Na+],,test
US20150361100A1,CC(C)(C)[Si](C)(C)Cl.Nc1ncnc2[nH]nc(-c3cc(O)cc(F)c3)c12>>CC(C)(C)[Si](C)(C)Oc1cc(F)cc(-c2n[nH]c3ncnc(N)c23)c1,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US20090286778A1,Clc1ncc(Cl)c(Cl)n1.Nc1cccc(NS(=O)(=O)c2cccc([N+](=O)[O-])c2)c1>>O=[N+]([O-])c1cccc(S(=O)(=O)Nc2cccc(Nc3nc(Cl)ncc3Cl)c2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04122255,C(=NCCc1ccccc1)c1ccccc1OCCCN1CCCCC1>>c1ccc(CCNCc2ccccc2OCCCN2CCCCC2)cc1,,CO,,[BH4-].[Na+],,test
US04919706,Clc1cscn1.SCc1ccccc1>>c1ccc(CSc2cscn2)cc1,,CCO,,C[O-].[Na+],,test
US04224325,CC(=N)CC#N.NNc1ccc(Cl)nn1>>Cc1cc(N)n(-c2ccc(Cl)nn2)n1,,CCO,,,,test
US20150152096A1,O=C(O)C=CC1CN(C(=O)OCc2ccccc2)CCO1>>O=C(O)CCC1CNCCO1,[Pd],,,,,test
US06239151B1,CC(C)CC(C(=O)NN(CC(C)C)C(=O)CN1CCCC1)[C@H](CC=Cc1ccccc1)C(=O)NOC1CCCCO1.Cc1ccc(S(=O)(=O)O)cc1>>CC(C)C[C@@H](C(=O)NN(CC(C)C)C(=O)CN1CCCC1)[C@H](C/C=C/c1ccccc1)C(=O)NO.Cc1ccc(S(=O)(=O)O)cc1,,CO,,O,,test
US20140374724A1,Brc1ccc2c(c1)oc1ccccc12.N>>Nc1ccc2c(c1)oc1ccccc12,,C1CCOC1,,,,test
US20120277207A1,CC(=O)Cl.CC(C)(C)OC(=O)N1CC(/C(N)=N/O)C1>>Cc1nc(C2CN(C(=O)OC(C)(C)C)C2)no1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20110275797A1,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(CCBr)ccc1OCc1ccccc1.CCN1CCNCC1>>CCN1CCN(CCc2ccc(OCc3ccccc3)c(C(=O)Nc3cc(-c4ccccc4)ccc3C(=O)OC(C)(C)C)c2)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080045543A1,CC(C)(C)OC(=O)N1CCN(c2ccc3c(ccn3[Si](C)(C)C(C)(C)C)c2)C(Cc2ccccc2)C1>>CC(C)(C)OC(=O)N1CCN(c2ccc3[nH]ccc3c2)C(Cc2ccccc2)C1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20070225292A1,CI.COc1ccc(N)c(C(=O)O)n1.Cc1ccc(C(=O)Cl)c2ccccc12>>COC(=O)c1nc(OC)ccc1NC(=O)c1ccc(C)c2ccccc12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,O=C([O-])[O-].[K+].[K+],test
US20110054175A1,CN1CC[C@]23C4=C5O[C@H]2[C@](OC(N)=O)(C(C)(C)C)C=C[C@H]3[C@H]1CC4=CCC5(Br)OO[SiH](C)C.O=S(=O)(c1ccccc1)N(F)S(=O)(=O)c1ccccc1>>CN1CC[C@]23C4=C5O[C@H]2[C@](OC(N)=O)(C(C)(C)C)C=C[C@H]3[C@H]1CC4=CCC5(F)OO[SiH](C)C,,C1CCOC1,,[Li]CCCC,,test
US20150376172A1,COc1ccc(C(NC2=N[C@](C)(c3cc(-c4nc5ccc(Cl)cc5o4)ccc3F)C[C@@H](C(F)(F)F)O2)(c2ccccc2)c2ccc(OC)cc2)cc1>>C[C@@]1(c2cc(-c3nc4ccc(Cl)cc4o3)ccc2F)C[C@@H](C(F)(F)F)OC(N)=N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030092749A1,CCn1c(=O)n(CC)c2cc(CC(=O)c3cccc(C)c3)ccc21.O=C(CBr)c1cccnc1>>CCn1c(=O)n(CC)c2cc(C(CC(=O)c3cccnc3)C(=O)c3cccc(C)c3)ccc21,,CC(=O)N(C)C,,[H-].[Na+],,test
US20040019063A1,C[Si](C)(C)C#N.[O-][n+]1cc(Br)c2ccccc2c1>>N#Cc1ncc(Br)c2ccccc12,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US03954983,CCC(=O)O.NNC(=S)NN>>CCc1nnc(S)n1N,,CCOCC,,,,test
US20060041123A1,CCOC(=O)CS.COC(=O)c1nc(N)c(Br)cc1F>>CCOC(=O)CSc1cc(F)c(C(=O)OC)nc1N,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20040024010A1,O=C1Cc2ccc(Cl)cc2N1.O=Cc1[nH]c2c(c1CCC(=O)O)CCCC2>>O=C(O)CCc1c(C=C2C(=O)Nc3cc(Cl)ccc32)[nH]c2c1CCCC2,,CCO,,C1CCNCC1,CC(=O)O,test
US20070197478A1,CCOC(=O)Nc1cc(Br)nc(Br)c1[N+](=O)[O-].Cc1ccc(CCl)cn1>>CCOC(=O)N(Cc1ccc(C)nc1)c1cc(Br)nc(Br)c1[N+](=O)[O-],,CC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20150152112A1,BrBr.CC(=O)c1ccc2c(c1)C(=O)OC(C)(C)O2>>CC1(C)OC(=O)c2cc(C(=O)CBr)ccc2O1,,CC(=O)O,,ClCCl,,test
US04171361,COc1cc(NC(=O)N2CCCC2)c(S(C)=O)cc1OC.Cc1cc(C)c(S(=O)(=O)ON)c(C)c1>>COc1cc(NC(=O)N2CCCC2)c(S(C)(=N)=O)cc1OC,,CC#N,,,,test
US06069170,COC=C(C(=O)OC)C(=O)OC.COc1ccc(N)cc1>>COC(=O)C(=CNc1ccc(OC)cc1)C(=O)OC,,CCO,,,,test
US20110112151A1,O=C(CSCc1cccnc1)C12CC3CC(CC(C3)C1)C2.O=C(OO)c1cccc(Cl)c1>>O=C(CS(=O)Cc1cccnc1)C12CC3CC(CC(C3)C1)C2,,ClCCl,,,,test
US20150126490A1,Nc1nccnc1-c1ccc(C(=O)N[C@H](CO)c2cccc(Cl)c2)c(F)c1.O=C1CCC(=O)N1Br>>Nc1ncc(Br)nc1-c1ccc(C(=O)N[C@H](CO)c2cccc(Cl)c2)c(F)c1,,CC#N,,,,test
US20050282827A1,Nc1cc(Cl)c(C(F)(F)F)cc1[N+](=O)[O-].OCC(F)(F)F>>Nc1cc(OCC(F)(F)F)c(C(F)(F)F)cc1[N+](=O)[O-],,CS(C)=O,O,Cl,[K+].[OH-],test
US20090286807A1,CC(C)(CNc1ccccc1Cl)NC(=O)OC(C)(C)C.O=C(Br)CBr>>CC(C)(CN(C(=O)CBr)c1ccccc1Cl)NC(=O)OC(C)(C)C,,CC(=O)N(C)C,,O=C([O-])O.[Na+],,test
US04762919,CC(=O)OCC(=O)[C@@]1(OC(C)=O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C>>CC(=O)OCC(=O)C1=CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]12C,,CN(C)C=O,,CC(=O)[O-].[K+],,test
US20050130970A1,COc1ccc(C2(C#N)CCCC2)cc1OC>>COc1ccc(C2(CN)CCCC2)cc1OC,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090181963A1,CC(C)n1nnc2c(N3CCOCC3)nc(-c3ccc(N)cc3)nc21.CN1CCN(C(=O)c2ccc(N)cc2)CC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)n1nnc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(C(=O)N5CCN(C)CC5)cc4)cc3)nc21,,ClCCl,,CCN(CC)CC,,test
US20150148311A1,Clc1ccc(Cl)c(CBr)c1.O=C([C@@H]1CCCN1)N1CCN(C2CC2)c2ccccc21>>O=C([C@@H]1CCCN1Cc1cc(Cl)ccc1Cl)N1CCN(C2CC2)c2ccccc21,,CC#N,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20120015958A1,COC(=O)c1ccc(CN2CCN(C(=O)c3ccc(NC(=O)NCC4CC4)cc3)CC2)s1>>O=C(NCC1CC1)Nc1ccc(C(=O)N2CCN(Cc3ccc(C(=O)O)s3)CC2)cc1,,CO,,[Na+].[OH-],,test
US20040132727A1,COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.O=C(N=C=S)c1ccc([N+](=O)[O-])cc1>>COc1cc2ncnc(Oc3ccc(NC(=S)NC(=O)c4ccc([N+](=O)[O-])cc4)cc3)c2cc1OC,,CCO,,Cc1ccccc1,,test
US20150274733A1,COC(=O)C1c2nc(NC3CCOCC3)ncc2C2(CCC2)N1C(=O)OCc1ccccc1>>c1nc(NC2CCOCC2)nc2c1C1(CCC1)NC2,,Cl,,,,test
US20150376130A1,COc1ccc(N)c(C(=O)O)c1.O=CCCC(F)(F)F>>COc1ccc(NCCCC(F)(F)F)c(C(=O)O)c1,,CC(=O)O,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100069381A1,CCOC(=O)c1ccnc(N)c1.O=C(Cl)CCc1ccccc1>>CCOC(=O)c1ccnc(NC(=O)CCc2ccccc2)c1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20060100246A1,COC(=O)C1CCCC(CO)C1>>COC(=O)C1CCCC(C=O)C1,,CS(C)=O,,CCN(CC)CC,,test
US20150210720A1,CCOc1nc(Cl)ccc1[N+](=O)[O-].COC(=O)CC(=O)OC(C)(C)C>>CCOc1nc(C(C(=O)OC)C(=O)OC(C)(C)C)ccc1[N+](=O)[O-],,CCOCC,CN(C)C=O,[H-].[Na+],,test
US20150065482A1,CC(=O)C#C[Si](C)(C)C.C[Si](C)(C)CCOCn1ccnn1>>CC(O)(C#C[Si](C)(C)C)c1cn(COCC[Si](C)(C)C)nn1,,C1CCOC1,,[Li]CCCC,,test
US20080058335A1,COCCn1c(C)c(C)sc1=N.O=C(Cl)c1c(C(F)(F)F)ccc(Cl)c1F>>COCCn1c(C)c(C)sc1=NC(=O)c1c(C(F)(F)F)ccc(Cl)c1F,,C1CCOC1,,CCN(CC)CC,,test
US20090029965A1,CC(C)(C)CCN1CCNCC1.O=C(Br)CBr>>CC(C)(C)CCN1CCN(C(=O)CBr)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20070037836A1,CC(C)(C)Nc1nc(Cl)nc2ccccc12.CC(C)(C)OC(=O)N[C@H]1CC[C@@H](N)CC1>>CC(C)(C)Nc1nc(NC2CCC(NC(=O)OC(C)(C)C)CC2)nc2ccccc12,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20110105491A1,CC(N)=S.COC(=O)C(=O)CCl>>COC(=O)c1cscn1,,CC#N,,,,test
US20080255147A1,NC(=S)N1CCN(C(=O)OCc2ccccc2)CC1.O=C(CBr)c1ccccc1F>>O=C(OCc1ccccc1)N1CCN(c2nc(-c3ccccc3F)cs2)CC1,,O,,C1CCOC1,CCN(C(C)C)C(C)C,test
US20090270451A1,CCS(=O)(=O)Cl.N#CC1(CC2CCOCC2)CC[NH2+]CC1>>CCS(=O)(=O)N1CCC(C#N)(CC2CCOCC2)CC1,,ClCCl,,CCN(CC)CC,,test
US20030004325A1,COc1ccc(C(Cl)(c2ccccc2)c2ccc(OC)cc2)cc1.C[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1ccc(=O)[nH]c1=S>>COc1ccc(C(OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=S)[C@H](C)[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20090036492A1,CN(C)C=O.FC(F)c1ccc2ccccc2c1Br>>O=Cc1c(C(F)F)ccc2ccccc12,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US05494925,CCCC(NS(N)(=O)=O)C(=O)OC>>CCCC1NS(=O)(=O)NC1=O,,CO,,C[O-].[Na+],,test
US06015774,COc1cc(-c2ncc(C(F)(F)F)n(C)c2=O)c(Cl)cc1Cl>>Cn1c(C(F)(F)F)cnc(-c2cc(O)c(Cl)cc2Cl)c1=O,,CC(=O)O,,Br,O,test
US20020037857A1,CCCCS(=O)(=O)N[C@H](CO)C(=O)O.C[C@H](N)C(=O)NCc1ccc(C#N)cc1.NO>>CCCCS(=O)(=O)N[C@H](CO)C(=O)O.C[C@H](N)C(=O)NCc1ccc(C(=N)NO)cc1,,CO,,CN1CCOCC1,Cl,test
US20070225292A1,O=C(NCC1CCC1)c1ncccc1NC(=O)c1ccc(C(=O)O)c2ccccc12>>O=C(NCC1CCC1)c1ncccc1NC(=O)c1ccc(CO)c2ccccc12,,CCOC(C)=O,,,,test
US20150315157A1,CCCCCCN=C=O.NCc1ccccc1>>CCCCCCNC(=O)NCc1ccccc1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,Cl,test
US20090270350A1,COc1ccc(Cn2c(C)cc(OCc3ccccc3C#N)c(C)c2=O)c(OC)c1>>COc1ccc(Cn2c(C)cc(OCc3ccccc3CN)c(C)c2=O)c(OC)c1,,C1CCOC1,,B,,test
US20070072853A1,NCC1CCCCC1.O=[N+]([O-])c1cc(NS(=O)(=O)c2ccccc2)ccc1F>>O=[N+]([O-])c1cc(NS(=O)(=O)c2ccccc2)ccc1NCC1CCCCC1,,CCO,O,,,test
US20110118221A1,CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N[C@@H]1c1ccc(C#N)cc1.COC(=O)CBr>>CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(CC(=O)OC)[C@@H]1c1ccc(C#N)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160207883A1,COc1cc(Cl)c([N+](=O)[O-])cn1.Oc1ccc(N2CC(OCCOC3CCCCO3)C2)cc1>>COc1cc(Oc2ccc(N3CC(OCCOC4CCCCO4)C3)cc2)c([N+](=O)[O-])cn1,,CN(C)C=O,,[H-].[Na+],,test
US20060106019A1,CCOC(=O)CCc1cnn2c(N(C)c3ccccc3)ncnc12.O>>O=C(O)CCc1cnn2c(=O)[nH]cnc12,,O,,CCO,[Na+].[OH-],test
US05308842,CCNC1CNS(=O)(=O)c2sccc21.CCOC(=O)CBr>>CCNC1CN(CC(=O)OCC)S(=O)(=O)c2sccc21,,CN(C)C=O,,[H-].[Na+],,test
US04626538,CC(=O)c1cccc(N)c1.O=C(Cl)C1CC1>>CC(=O)c1cccc(NC(=O)C2CC2)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20140031364A1,COC(=O)CC#N.ON=C(Cl)c1cccc(C(F)(F)F)c1>>COC(=O)c1c(-c2cccc(C(F)(F)F)c2)noc1N,,CO,,C[O-].[Na+],,test
US20140194437A1,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21.CC(C)(C)OC(N)=O.ClCCl>>CC(C)(C)OC(=O)NC1CC(CC=O)C1,,ClCCl,,,,test
US20150104384A1,N#Cc1ccc(S(=O)(=O)C2CCN(C3CCOCC3)CC2)cc1>>NCc1ccc(S(=O)(=O)C2CCN(C3CCOCC3)CC2)cc1,[Ni],N,,[H][H],,test
US20150274767A1,C#C[C@]1(CO)O[C@@H](c2cnc3c(N)ncnn23)C[C@@H]1O[Si](C)(C)C(C)(C)C>>C#C[C@]1(CO)O[C@@H](c2cnc3c(N)ncnn23)C[C@@H]1O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040087632A1,C[Si](C)(C)C#N.Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1.O=CCc1ccccc1>>N#CC(Cc1ccccc1)Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1,,ClCCl,O,,,test
US20080132519A1,COc1ccc(N(C)C=C2SC(=S)N(Cc3ccccc3)C2=O)cc1>>CN(C=C1SC(=S)N(Cc2ccccc2)C1=O)c1ccc(O)cc1,,ClCCl,,BrB(Br)Br,,test
US20120015941A1,CC(=O)OC1C[C@H](c2csc(NC(=O)NCc3ccc(Cl)c(Cl)c3)n2)N(C(=O)OC(C)(C)C)C1.Cl>>CC(=O)O[C@H]1CNC(c2csc(NC(=O)NCc3ccc(Cl)c(Cl)c3)n2)C1.Cl,,C1COCCO1,Cl,,,test
US20090192138A1,CC#CCn1c(N2CCC[C@@H](NC(=O)OC(C)(C)C)C2)c(C#N)c2ncn(CC(=O)c3ccccc3)c(=O)c21>>CC#CCn1c(N2CCC[C@@H](N)C2)c(C#N)c2ncn(CC(=O)c3ccccc3)c(=O)c21,,ClCCl,O=C(O)C(F)(F)F,,,test
US20070049612A1,CCC1C(=O)C(=CN(C)C)C2CCCC1N2S(=O)(=O)c1ccc(Cl)cc1.NN>>CCC1c2[nH]ncc2C2CCCC1N2S(=O)(=O)c1ccc(Cl)cc1,,CC(=O)O,,O,,test
US04259504,CN(C)C=NC(=O)c1cnccn1.NNc1ccc([N+](=O)[O-])cc1>>O=[N+]([O-])c1ccc(-n2ncnc2-c2cnccn2)cc1,,C1COCCO1,,CC(=O)O,,test
US04533661,CCOC(=O)CN1CCC[C@H](NP(=O)(CC(Cc2ccccc2)N2C(=O)c3ccccc3C2=O)OCC)C1=O>>CCOC(=O)CN1CCC[C@H](NP(=O)(CC(Cc2ccccc2)NC(=O)c2ccccc2)OCC)C1=O,,C1COCCO1,,NN,O,test
US20040186091A1,COC(=O)CBr.Clc1ccc2c(c1)CNCc1nnc(C3CCN(c4ccccn4)CC3)n1-2>>COC(=O)CN1Cc2cc(Cl)ccc2-n2c(nnc2C2CCN(c3ccccn3)CC2)C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05179125,CC(=O)SCC(Cc1ccccc1)C(=O)Cl.Nc1cccc(C(=O)O)c1>>CC(=O)SCC(Cc1ccccc1)C(=O)Nc1cccc(C(=O)O)c1,,ClC(Cl)Cl,O,CCN(CC)CC,Cl,test
US20150225422A1,C=CCBr.Cc1ncc(Br)cc1NS(=O)(=O)/C=C/c1ccccc1>>C=CCN(c1cc(Br)cnc1C)S(=O)(=O)/C=C/c1ccccc1,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US20110269738A1,CCc1c(Br)cccc1C=O>>CCc1c(Br)cccc1CO,,CO,,[BH4-].[Na+],,test
US06080743,CCOC(=O)CNCc1ccccn1.COc1nc2cc([N+](=O)[O-])cc(CBr)c2nc1OC>>CCOC(=O)CN(Cc1ccccn1)Cc1cc([N+](=O)[O-])cc2nc(OC)c(OC)nc12,,CC#N,,CCN(CC)CC,,test
US06395739B1,COc1ccccc1N1CCN(CC[C@H](Oc2ccc(C(=O)c3c[nH]c4ccccc34)cc2)c2ccc(C)cc2)CC1>>COc1ccccc1N1CCN(CC[C@H](Oc2ccc(C(=O)c3c[nH]c4ccccc34)cc2)c2ccc(C)cc2)CC1,,ClCCl,,Cl,,test
US20020107251A1,Nc1cccc(-c2cccc(-n3c(=O)c(Cc4cccnc4)nc4cccnc43)c2)c1.O=C1OC(=O)c2ccccc21>>O=C(O)c1ccccc1C(=O)Nc1cccc(-c2cccc(-n3c(=O)c(Cc4cccnc4)nc4cccnc43)c2)c1,,C1COCCO1,O,,,test
US20130109678A1,CN(C)N.Nc1cc(Cl)ccc1[N+](=O)[O-]>>CN(C)Nc1ccc([N+](=O)[O-])c(N)c1,,CC(=O)N(C)C,,O,O=C([O-])[O-].[K+].[K+],test
US20160218303A1,N#Cc1cccc(Nc2ccc3c(c2)oc2ccccc23)c1[N+](=O)[O-]>>N#Cc1cccc(Nc2ccc3c(c2)oc2ccccc23)c1N,,CCO,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20120208797A1,CCCCCCc1ccc(O)cc1.Cn1c(Cl)nc(-c2ccncn2)cc1=O>>CCCCCCc1ccc(Oc2nc(-c3ccncn3)cc(=O)n2C)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US04734416,O=C1CCc2ccc(OCC(O)CCl)cc2N1.c1ccc(N2CCNCC2)cc1>>O=C1CCc2ccc(OCC(O)CN3CCN(c4ccccc4)CC3)cc2N1,,ClC(Cl)Cl,,CN(C)C=O,,test
US20100331326A1,Cc1ccncc1N1CCNC1=O.Ic1ccc2scnc2c1>>Cc1ccncc1N1CCN(c2ccc3scnc3c2)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20070167488A1,Cc1[nH]c(C=O)c(C)c1Br.O=C1Cc2ccccc2N1O>>Cc1[nH]c(C=C2C(=O)N(O)c3ccccc32)c(C)c1Br,C1CCNCC1,CCO,,,,test
US20150011548A1,CCOC(=O)CN1CCCCC1>>O=C(O)CN1CCCCC1,,Cl,,,,test
US20080261969A1,Nc1ccc(C(F)(F)F)cc1N.S=C(n1ccnc1)n1ccnc1>>FC(F)(F)c1ccc2nc(S)[nH]c2c1,,C1CCOC1,,,,test
US04053601,COS(=O)(=O)OC.Oc1ccc(-c2ccc(Cl)nn2)c(O)c1>>COc1ccc(-c2ccc(Cl)nn2)c(O)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090099187A1,CN[C@H]1CCc2cccc(OC)c2C1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1cccc2c1C[C@@H](N(C)C(=O)C(F)(F)F)CC2,,ClCCl,,c1ccncc1,,test
US04845219,COC(COCCC(C)CCCC(C)CCCC(C)CCCC(C)C)CS(=O)(=O)CCCO.CS(=O)(=O)Cl>>COC(COCCC(C)CCCC(C)CCCC(C)CCCC(C)C)CS(=O)(=O)CCCOS(C)(=O)=O,,CCN(CC)CC,,CCOC(C)=O,,test
US20100034740A1,CC(C)(C)[Si](OCCCCBr)(c1ccccc1)c1ccccc1.CN(O)C(=O)OC(C)(C)C>>CN(OCCCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)C(=O)OC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20140364412A1,CC(C)(C)c1cc(N)n(-c2ccc(Cl)c(O)c2)n1.OCCCOC1CCCCO1>>CC(C)(C)c1cc(N)n(-c2ccc(Cl)c(OCCCOC3CCCCO3)c2)n1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130210768A1,Cc1ccc(C(C)(C)N=[N+]=[N-])cc1-c1ccc2c(n1)n(C)c(=O)n2CC(C)(C)C>>Cc1ccc(C(C)(C)N)cc1-c1ccc2c(n1)n(C)c(=O)n2CC(C)(C)C,[Pd],CCO,,,,test
US20160176850A1,COc1ccnc2[nH]cc(C3CCN(C(=O)OC(C)(C)C)CC3)c12>>COc1ccnc2[nH]cc(C3CCNCC3)c12,,ClCCl,,CCOC(C)=O,Cl,test
US20150291582A1,CC(C)N.Cc1cc(Cn2cc3c(C(=O)O)nccc3n2)cnc1OCC(F)(F)F>>Cc1cc(Cn2cc3c(C(=O)NC(C)C)nccc3n2)cnc1OCC(F)(F)F,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20010027196A1,CCCN.CS(=O)(=O)c1nc(N)nc(-c2ccccc2)c1C#N>>CCCNc1nc(N)nc(-c2ccccc2)c1C#N,,COCCOC,,,,test
US20090264411A1,CCOC(=O)c1c(Nc2ccc(I)cc2F)sc2c1CC(C)(C)CNC2=O>>CC1(C)CNC(=O)c2sc(Nc3ccc(I)cc3F)c(C(=O)O)c2C1,,C1CCOC1,O,[Li+].[OH-],,test
US20150025244A1,COc1ccc2ncc([N+](=O)[O-])c(O)c2n1.O=P(Cl)(Cl)Cl>>COc1ccc2ncc([N+](=O)[O-])c(Cl)c2n1,,CN(C)C=O,,,,test
US20060229343A1,CI.CON=C1C[C@@H](c2nc(C3CCNCC3)no2)N(C(=O)c2ccc(-c3ccccc3)cc2)C1>>CON=C1C[C@@H](c2nc(C3CCN(C)CC3)no2)N(C(=O)c2ccc(-c3ccccc3)cc2)C1,,ClCCl,,CCN(CC)CC,O=C([O-])[O-].[Na+].[Na+],test
US06420418B1,CC1CC(=O)C(C)(C(=O)OC(C)(C)C)O1.COC(=O)CP(=O)(OC)OC>>COC(=O)CC1CC(C)OC1(C)C(=O)O,,CO,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20050107364A1,CC(C)(C)CC[C@@]1(C)C(=O)C(C2=NS(=O)(=O)c3c(CN)csc3N2)=C(O)c2ccccc21.CS(=O)(=O)Cl>>CC(C)(C)CC[C@@]1(C)C(=O)C(C2=NS(=O)(=O)c3c(CNS(C)(=O)=O)csc3N2)=C(O)c2ccccc21,,CN(C)C=O,O,CCN(CC)CC,,test
US20050032786A1,CC(C)(C)OC(=O)c1ccccn1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)OC(=O)c1cccc[n+]1[O-],,CCOC(C)=O,,,,test
US20150111870A1,COc1nc2ccc(C(=O)c3cnc(C)n3C)cc2c(Cl)c1CN1CCC(n2cccn2)CC1.Cn1ccnn1>>COc1nc2ccc(C(O)(c3cnnn3C)c3cnc(C)n3C)cc2c(Cl)c1CN1CCC(n2cccn2)CC1,,C1CCOC1,,[Li]CCCC,,test
US20100249071A1,C=CCBr.COC(=O)c1cnc(NC(C)C)c(Cl)c1>>C=CCN(c1ncc(C(=O)OC)cc1Cl)C(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20130338179A1,CCCc1cc(=O)[nH]c(SC)n1.Nc1ccc(F)c(C(F)(F)F)c1>>CCCc1cc(=O)[nH]c(Nc2ccc(F)c(C(F)(F)F)c2)n1,,CCOC(C)=O,,,,test
US20090298827A1,COc1ccccc1NCc1c(-c2ccc(O)cc2OC)ccc2c1C(C)=CC(C)(C)N2.O=C(Cl)c1ccccc1>>COc1ccccc1NCc1c(-c2ccc(OC(=O)c3ccccc3)cc2OC)ccc2c1C(C)=CC(C)(C)N2,,ClCCl,,CCN(CC)CC,,test
US04929741,C#CC(=O)OCCOCCOC.O=Cc1ccc2c(c1)OCO2>>COCCOCCOC(=O)C#CC(O)c1ccc2c(c1)OCO2,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20100063065A1,COc1ccc(C(=O)c2ccsc2N)cn1.O=C1CCC(=O)N1Cl>>COc1ccc(C(=O)c2cc(Cl)sc2N)cn1,,CCOC(C)=O,CN(C)C=O,,,test
US20130281433A1,COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3cnc(C)c(-c4ccc5c(cnn5C)n4)c3)sc2c1-c1ccc(Cl)cc1>>Cc1cc2nc(-c3cnc(C)c(-c4ccc5c(cnn5C)n4)c3)sc2c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20070021468A1,COC(=O)C(Br)CC(=O)Cl.NN=c1[nH]cccc1Cl>>COC(=O)C1CC(=O)NN1c1ncccc1Cl,,CC#N,,O=C([O-])O.[Na+],,test
US06191124B1,CCOC(=O)c1cnc2sc3c(n12)CCCCC3>>OCc1cnc2sc3c(n12)CCCCC3,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080090856A1,CC1(C)OB(c2ccc3c(c2)CCN(C(=O)OCc2ccccc2)C3)OC1(C)C>>O=C(OCc1ccccc1)N1CCc2cc(B(O)O)ccc2C1,,C1CCOC1,O,Cl,,test
US20130289012A1,O=C(OCC1c2ccccc2-c2ccccc21)ON1C(=O)CCC1=O.O=C1N2C[C@@H](CC[C@H]2c2nc(C3CCNCC3)no2)N1OCc1ccccc1>>O=C(OCC1c2ccccc2-c2ccccc21)N1CCC(c2noc([C@@H]3CC[C@@H]4CN3C(=O)N4OCc3ccccc3)n2)CC1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20080214622A1,CI.O=C(O)c1ccc(Br)cc1O>>COc1cc(Br)ccc1C(=O)O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090281142A1,CC(=O)OCC(COC(C)=O)CC(=O)CBr.NC(N)=S>>CC(=O)OCC(COC(C)=O)Cc1csc(N)n1,,CCO,,,,test
US20160031892A1,COC(=O)C(C)c1ccc(Cl)cc1Cl>>CC(C(=O)O)c1ccc(Cl)cc1Cl,,CO,O,[Na+].[OH-],,test
US20130237571A1,COC(=O)[C@@H]1C[C@H]1c1ccc([N+](=O)[O-])cc1>>COC(=O)[C@@H]1C[C@H]1c1ccc(N)cc1,[Pd],CCOC(C)=O,,CO,,test
US20090048225A1,CON.O=Cc1ccc(Br)s1.c1ccncc1>>CON=Cc1cnc(Br)s1,,ClCCl,,Cl,,test
US20160159794A1,N#Cc1ccc(Nc2ccc(Cl)cc2[N+](=O)[O-])cn1>>N#Cc1ccc(Nc2ccc(Cl)cc2N)cn1,[Ni],CO,,,,test
US20120190666A1,Cc1nc(N)cc(-c2c(Nc3cc[nH]n3)nc3cccnn23)n1.Clc1nc2ccccc2[nH]1>>Cc1nc(N)cc(-c2c(Nc3ccn(-c4nc5ccccc5[nH]4)n3)nc3cccnn23)n1,,CCC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20160115126A1,C=O.Cc1[nH]c2c(C#N)cc(F)c(N[C@H]3CCN(C(=O)OCc4ccccc4)C3)c2c1C>>Cc1[nH]c2c(C#N)cc(F)c(N(C)[C@H]3CCN(C(=O)OCc4ccccc4)C3)c2c1C,,CCOC(C)=O,CO,CC(=O)O,[BH3-]C#N.[Na+],test
US20050176742A1,CCOC(=O)c1c(NC(C)=O)sc2c(O)cc(Cc3ccccc3)cc12>>CCOC(=O)c1c(N)sc2c(O)c(Cc3ccccc3)ccc12,,CO,,O=S(=O)(O)O,,test
US20090298823A1,CC(C)(C)OC(=O)NCC1CCCCN1c1nc(Nc2ccc3cn[nH]c3c2)ncc1F>>NCC1CCCCN1c1nc(Nc2ccc3cn[nH]c3c2)ncc1F,,O=C(O)C(F)(F)F,,,,test
US20130338367A1,C=C(OC)C(=O)OC.CS>>COC(=O)C(CSC)OC,,CC#N,,O,[Na],test
US20040048916A1,CCOC(=O)CC1c2cc(C(F)(F)F)ccc2C(=O)N1CC1CC1>>O=C(O)CC1c2cc(C(F)(F)F)ccc2C(=O)N1CC1CC1,,CCO,,[Na+].[OH-],,test
US04028415,CC(=O)OC(CN(C)C)C(c1ccccc1)c1ccccc1>>CN(C)CC(O)C(c1ccccc1)c1ccccc1,,[K+],[OH-],,,test
US20150191476A1,O=Cc1cnn2ccccc12>>O=Cc1cnn2c1CCCC2,[Pd],CCO,,,,test
US20080004271A1,N#Cc1c(Cl)nc(CC2CC2)nc1-c1ccc(Cl)c(Cl)c1.NC(=O)CS>>N#Cc1c(SCC(N)=O)nc(CC2CC2)nc1-c1ccc(Cl)c(Cl)c1,,CCO,ClCCl,,,test
US04826815,COC(=O)[C@](Cc1ccc(OC)cc1)(N=C=O)N(C)CC(O)CO>>COc1ccc(C[C@](N=C=O)(C(=O)O)N(C)CC(O)CO)cc1,,C1COCCO1,O,Cl,,test
US05728848,O=CC1CCOC2(CCCCC2)OC1>>OCC1CCOC2(CCCCC2)OC1,,CO,,[BH4-].[Na+],,test
US04855298,CCOC(=O)Cl.O=C1Nc2ccc(Cl)cc2C1=O>>CCOC(=O)N1C(=O)C(=O)c2cc(Cl)ccc21,,CCN(CC)CC,,C1CCOC1,,test
US20120040999A1,[N-]=[N+]=NCc1nnc(-c2ccn[nH]2)s1>>NCc1nnc(-c2ccn[nH]2)s1,,CO,,Cl[Sn]Cl,,test
US20020013466A1,CCOC(=O)COc1ccccc1Oc1cc(NC(C)=O)c(F)cc1Cl>>CCOC(=O)COc1ccccc1Oc1cc(N)c(F)cc1Cl,,CO,,,,test
US20120065204A1,CN(C)C=O.CO.O=C(O)C1=Cc2cc(Br)ccc2OC1>>COC(=O)c1ccc2c(c1)C=C(C(=O)O)CO2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,CCN(CC)CC,,test
US20100029589A1,CCOC(=O)CCC(C)(C)c1ccc(F)cc1.CNOC>>CON(C)C(=O)CCC(C)(C)c1ccc(F)cc1,,C1CCOC1,,CC(C)[Mg]Cl,Cl,test
US20140288123A1,CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)cn1.Cc1cc(C)c(CNC(=O)c2ccc(Oc3cccc(Br)c3C#N)c(Cl)c2)c(O)n1>>Cc1cc(C)c(CNC(=O)c2ccc(Oc3cccc(-c4cn[nH]c4)c3C#N)c(Cl)c2)c(O)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US03932416,COc1cc(C(=O)O)nc2ccccc12.Nc1nnn[nH]1>>COc1cc(C(=O)Nc2nnn[nH]2)nc2ccccc12,,CN(C)C=O,,,,test
US04482552,CC(=O)OC(c1ccccc1)c1nc(NCCCOc2cccc(C=O)c2)n(C)n1.NCc1ccco1>>Cn1nc(C(O)c2ccccc2)nc1NCCCOc1cccc(CNCc2ccco2)c1,,CCO,,O,[BH4-].[Na+],test
US20100136136A1,CN1CCNCC1.Nc1ccc(OCCCBr)cc1[N+](=O)[O-]>>CN1CCN(CCCOc2ccc(N)c([N+](=O)[O-])c2)CC1,,O,,,,test
US20040215019A1,CC(C)(C)OC(=O)N1CCC(CCN2Cc3c(N)cccc3C2=O)CC1.O=C(Cl)c1ccc(Cl)s1>>CC(C)(C)OC(=O)N1CCC(CCN2Cc3c(NC(=O)c4ccc(Cl)s4)cccc3C2=O)CC1,CN(C)c1ccncc1,C1CCOC1,,c1ccncc1,,test
US20130137672A1,Cc1ccc(S(=O)(=O)N2CC3CCN(C(=O)OC(C)(C)C)CC32)c(C)c1>>Cc1ccc(S(=O)(=O)N2CC3CCNCC32)c(C)c1,,C1COCCO1,,O=C(O)C(F)(F)F,,test
US20090054435A1,COCOc1ccc(OC)cc1C(=O)c1ccc(OCc2nc(-c3ccccc3)oc2C)cc1>>COc1ccc(O)c(C(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c1,,CC(C)=O,,Cl,,test
US05994378,CCCC(C#N)Oc1ccccc1COc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1.NO>>CCCC(Oc1ccccc1COc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1)C(N)=NO,,CO,CS(C)=O,Cl,C[O-].[Na+],test
US20020028835A1,CCCCc1ccc(S(=O)(=O)Nc2ccc(N3CCC(=O)CC3)cc2)cc1.CCOC(=O)CBr>>CCCCc1ccc(S(=O)(=O)N(CC(=O)OCC)c2ccc(N3CCC(=O)CC3)cc2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US06166074,CC(=O)OC(C)=O.O=Cc1cccs1.O=S(=O)(O)O>>CC(=O)O.CC(=O)O.O=Cc1cccs1,O=S(=O)(O)O,ClC(Cl)Cl,,,,test
US20060094778A1,CCC(CC)(c1ccc(CNCCS(C)(=O)=O)c(C)c1)c1ccc(OCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1>>CCC(CC)(c1ccc(CNCCS(C)(=O)=O)c(C)c1)c1ccc(OCC(O)C(C)(C)C)c(C)c1,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100273767A1,CC(C)(C)OC(=O)N1CCNC(CC(=O)O)C1.O=[N+]([O-])c1cc(Cl)c(Cl)cc1F>>CC(C)(C)OC(=O)N1CCN(c2cc(Cl)c(Cl)cc2[N+](=O)[O-])C(CC(=O)O)C1,,CN(C)C=O,O,CCN(CC)CC,,test
US05534518,Cc1c(Br)ccc(N)c1C#N.OB(O)c1cc(F)cc(C(F)(F)F)c1>>Cc1c(-c2cc(F)cc(C(F)(F)F)c2)ccc(N)c1C#N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,O,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20120071524A1,CON(C)C(=O)c1cc(-c2ccccc2)ncn1.COc1cc([Mg]Br)cc(OC)c1OC>>COc1cc(C(=O)c2cc(-c3ccccc3)ncn2)cc(OC)c1OC,,C1CCOC1,,,,test
US20160002246A1,COC(=O)c1ccc(C)o1.O=C1CCC(=O)N1Br>>COC(=O)c1ccc(CBr)o1,,CCOC(C)=O,,,,test
US20130210795A1,N#Cc1c(N)nc(Sc2ccccc2)c(C#N)c1-c1ccc(OCCO)cc1.O=C(O)c1cccc(CO)c1>>N#Cc1c(N)nc(OCc2cccc(C(=O)O)c2)c(C#N)c1-c1ccc(OCCO)cc1,,COCCOC,O,Cl,CC(C)(C)[O-].[K+],test
US20040186102A1,COc1ccc(CCC2NCCc3cc(OC)c(OC)cc32)cc1OC.O=[N+]([O-])c1ccc(Cl)c(OCCBr)c1>>COc1ccc(CCC2c3cc(OC)c(OC)cc3CCN2CCOc2cc([N+](=O)[O-])ccc2Cl)cc1OC,,C1CCOC1,,c1ccncc1,,test
US20020183361A1,CC[C@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(Cl)s1>>CC[C@H](C)[C@@H](C=O)NS(=O)(=O)c1ccc(Cl)s1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US04332804,BrCCc1c[nH]c2ccccc12.O=C1COC2(CCNCC2)CN1>>O=C1COC2(CCN(CCc3c[nH]c4ccccc34)CC2)CN1,,CCN(CC)CC,CN(C)C=O,O,,test
US04345100,COC(C)(C)C.N#CC(=O)c1ccccc1.O=S(=O)(O)O>>CC(C)(C)NC(=O)C(=O)c1ccccc1,,CC(=O)O,,,,test
US20070238726A1,CC(C)(C)OC(=O)N1CC2CNCC2C1.COc1ccc(Cn2nc(I)c3c(Oc4ccc(N)cc4F)ccnc32)cc1>>COc1ccc(Cn2nc(N3CC4CN(C(=O)OC(C)(C)C)CC4C3)c3c(Oc4ccc(N)cc4F)ccnc32)cc1,[Cu]I,CS(C)=O,,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US20100216814A1,CNC(=O)c1cccc(C(C)=CBr)c1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>CNC(=O)C1(n2c3c(c4cc(C)ccc42)CN(C)CC3)C=CC=CC1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20030149038A1,BrCc1ccccc1.COC(=O)c1ccc(N)c(B2OC(C)(C)C(C)(C)O2)c1>>COC(=O)c1ccc(N)c(Cc2ccccc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20040116480A1,COc1ccnc(F)c1CO.O=S(Cl)Cl>>COc1ccnc(F)c1CCl,,c1ccccc1,,,,test
US20080070893A1,CCOC(=O)c1cccc(Nc2cc(Cl)nc3c(CCCCC#N)cnn23)c1.Nc1cccc(N)c1>>CCOC(=O)c1cccc(Nc2cc(Nc3cccc(N)c3)nc3c(CCCCC#N)cnn23)c1,,CCOC(C)=O,CN1CCCC1=O,,,test
US05464781,CCOC(=O)c1cnc2nc(C=CC(=O)O)c(OCC)cc2c1Nc1ccc(OC)cc1.Cl>>CCOC(=O)c1cnc2nc(CCC(=O)O)c(OCC)cc2c1Nc1ccc(OC)cc1.Cl,[Pd],,,[H][H],,test
US20120004203A1,CC(C)CC(=O)Cl.CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(N)nc2N1c1cccc(C(F)(F)F)c1>>CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(NC(=O)CC(C)C)nc2N1c1cccc(C(F)(F)F)c1,,c1ccncc1,,Cl,,test
US20030199550A1,CCN.CN(CC[C@@H]1CC[C@@H](/C=C/CCl)CC1)S(=O)(=O)c1ccc(C(F)(F)F)cc1>>CCNC/C=C/[C@@H]1CC[C@@H](CCN(C)S(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1,,CC(=O)N(C)C,,,,test
US20140179733A1,CC(C)c1c(N)cnn1-c1ccc(F)cc1.Cc1nc(C(F)(F)F)cn1C(C)C(=O)O>>Cc1nc(C(F)(F)F)cn1C(C)C(=O)Nc1cnn(-c2ccc(F)cc2)c1C(C)C,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160052943A1,B1C2CCCC1CCC2.B1C2CCCC1CCC2>>B1C2CCCC1CCC2.B1C2CCCC1CCC2,,C1CCOC1,,O=C=O,,test
US20100137397A1,CCOC(=O)C(C[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)sc2[nH]1)C(=O)OCC>>CCOC(=O)CC[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)sc2[nH]1,,CS(C)=O,O,[Cl-].[Na+],,test
US20040063707A1,COc1cnc2[nH]ccc2c1.O=S(=O)(Cl)c1ccccc1>>COc1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1,,C1CCOC1,,[H-].[Na+],,test
US20090269301A1,CCOC(=O)C(=O)CC(C)=O.Nc1ccc2[nH]cnc2c1.O=Cc1cc(Br)ccc1F>>CC(=O)C1=C(O)C(=O)N(c2ccc3[nH]cnc3c2)C1c1cc(Br)ccc1F,,CCO,,,,test
US04983600,NC(=O)NC(=O)c1cc(Cl)cc(Cl)c1.NC1CN2CCC1CC2>>O=C(NC(=O)c1cc(Cl)cc(Cl)c1)NC1CN2CCC1CC2,,c1ccncc1,,,,test
US20050020684A1,COC(=O)C(OC)C(O)c1cccc(OCc2ccccc2)c1>>COC(=O)C(=Cc1cccc(OCc2ccccc2)c1)OC,CN(C)c1ccncc1,CCOCC,ClCCl,CS(=O)(=O)Cl,,test
US05880147,CCCCCC(CC(=O)Nc1cc(C(=O)OC)ccc1C(C)(C)C)c1ccc(C)cc1OC>>CCCCCC(CC(=O)Nc1cc(C(=O)O)ccc1C(C)(C)C)c1ccc(C)cc1OC,,CO,,[Na+].[OH-],,test
US20140148468A1,CC(C)CCN.O=C(O)c1ccccc1SCCC(F)(F)c1ccc(F)cc1>>CC(C)CCNC(=O)c1ccccc1SCCC(F)(F)c1ccc(F)cc1,,C1CCOC1,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110009395A1,Brc1cccc(Br)c1.O=c1ccocc1>>OC1(c2cccc(Br)c2)CCOCC1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20040006071A1,CCN1c2ncc(CCO)cc2C(=O)N(C)c2cccnc21.COC(=O)c1ccc(-c2ccc(O)c(C)c2)cc1>>CCN1c2ncc(CCOc3ccc(-c4cccc(C(=O)OC)c4)cc3C)cc2C(=O)N(C)c2cccnc21,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060014777A1,CCNCC.O=C(O)c1ccc(Cl)cc1C(F)(F)F>>CCN(CC)C(=O)c1ccc(Cl)cc1C(F)(F)F,,ClCCl,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20100249396A1,CCOC(=O)CC1Cc2ccc(O)cc2CN(CC(F)(F)F)C1=O.OCCc1cn2nccnc2n1>>CCOC(=O)CC1Cc2ccc(OCCc3cn4nccnc4n3)cc2CN(CC(F)(F)F)C1=O,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080015202A1,CCOC(=O)c1nc(CCl)cs1>>O=C(O)c1nc(CCl)cs1,,CCO,,Cl,[Na+].[OH-],test
US20030119878A1,Cc1occc(=O)c1OC[C@@](N)(C(=O)OC(C)(C)C)c1ccccc1.NCc1c(F)cccc1F>>Cc1c(OC[C@@](N)(C(=O)OC(C)(C)C)c2ccccc2)c(=O)ccn1Cc1c(F)cccc1F,,CCO,,,,test
US05349067,CCCCCCCCCCCCc1ccc(S(=O)(=O)Cl)cc1.CN(C)c1ccccc1.Cc1ccc(CO)cc1>>CCCCCCCCCCCCc1ccc(S(=O)(=O)[O-])cc1.Cc1ccc(C[N+](C)(C)c2ccccc2)cc1,,C1COCCO1,,CC(C)(C)[O-].[K+],,test
US20130023541A1,CCc1ccc(CBr)cc1.CN[C@H]1CCN(c2ncccc2C(=O)OC(C)C)C1>>CCc1ccc(CN(C)[C@H]2CCN(c3ncccc3C(=O)OC(C)C)C2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030207865A1,CC(=O)Cl.Cc1cccc(N)c1C>>CC(=O)Nc1cccc(C)c1C,,ClCCl,,CCN(CC)CC,Cl,test
US20010039348A1,C1=CCCCC1.Cc1cc([N+](=O)[O-])ccc1NC(=O)c1ccccc1F>>Cc1cc(N)ccc1N(C(=O)c1ccccc1F)c1ccccc1,[Pd],O,,CCO,,test
US20090176786A1,CNc1ccc(SC(F)(F)C(F)(F)F)c(C)c1C.O=C=NC(=O)c1c(F)cccc1F>>Cc1c(SC(F)(F)C(F)(F)F)ccc(N(C)C(=O)NC(=O)c2c(F)cccc2F)c1C,,COC(C)(C)C,,,,test
US05087629,CCC1CCCCN1C(=O)C=Cc1c(-c2cccc(N)c2)nn2ccccc12.CS(=O)(=O)Cl>>CCC1CCCCN1C(=O)C=Cc1c(-c2cccc(NS(C)(=O)=O)c2)nn2ccccc12,,ClCCl,,CCN(CC)CC,,test
US20030114311A1,C=C(OCC)c1cc(NC(C)=O)c(Cl)c(C(=O)OC)n1.O=C1CCC(=O)N1Br>>COC(=O)c1nc(C(=O)CBr)cc(NC(C)=O)c1Cl,,C1CCOC1,O,,,test
US20040171655A1,CC(=Cc1ccccc1)CNCCCN1CCCC1C.COc1cc(C(=O)O)cc(OC)c1OC>>COc1cc(C(=O)N(CCCN2CCCC2C)CC(C)=Cc2ccccc2)cc(OC)c1OC,,CCOC(C)=O,CCOCC,CCN(CC)CC,Cl,test
US20080234261A1,CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(NC(=O)c4ccc(=O)[nH]c4)c3)cc21.ClCCN1CCOCC1>>CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN5CCOCC5)nc4)c3)cc21,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20140094474A1,CCOC(=O)C(=O)CBr.Nc1cc[nH]c(=O)n1>>CCOC(=O)c1cn2c(=O)[nH]ccc2n1,,CCO,,,,test
US20150183741A1,CCOC(=O)C1CCNCC1.C[C@H]1CC[C@@H](Oc2ccc3c(C=O)cccc3c2C(F)(F)F)CC1>>CCOC(=O)C1CCN(Cc2cccc3c(C(F)(F)F)c(O[C@@H]4CC[C@H](C)CC4)ccc23)CC1,,ClCCl,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140371449A1,CO.COC(C)(C)OC.O=C[C@H](O)[C@H](O)[C@H](O)CO>>COC1O[C@H](CO)[C@H]2OC(C)(C)O[C@@H]12,,CO,,CC(C)=O,,test
US20160017219A1,CC(C)c1cccc(C(C)C)c1-n1c(=O)c2cc(Br)c3oc4ccccc4c4c(Oc5ccccc5)cc(c1=O)c2c34>>CC(C)c1cccc(C(C)C)c1-n1c(=O)c2ccc3oc4ccccc4c4c(Oc5ccccc5)cc(c1=O)c2c34,[Pd],C1CCOC1,CO,,,test
US20160221972A1,CC(C)OC(=O)c1ccc2c(n1)OCCNC2.COc1ccc(C=O)cc1>>COc1ccc(CN2CCOc3nc(C(=O)OC(C)C)ccc3C2)cc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04227014,O=C(O)c1ccc(NCCCCCCCCC2CCCCC2)cc1.OCC(O)CO>>O=C(OCC(O)CO)c1ccc(NCCCCCCCCC2CCCCC2)cc1,,Cc1ccccc1,,CCOCC,FB(F)F,test
US20040044057A1,O=C(CBr)c1cccs1>>OC(CBr)c1cccs1,,CO,,[BH4-].[Na+],,test
US20070161686A1,Cc1onc(-c2ccccc2)c1-c1nnc(-c2ccc(C(=O)O)cc2)o1.O=C(n1ccnc1)n1ccnc1>>Cc1onc(-c2ccccc2)c1-c1nnc(-c2ccc(C(=O)n3ccnc3)cc2)o1,,C1CCOC1,,,,test
US04435406,CC(=O)Nc1cc2c(cc1[N+](=O)[O-])OCCCO2>>Nc1cc2c(cc1[N+](=O)[O-])OCCCO2,,CO,,Cl,,test
US04098791,CO.N#CN1CCCC1>>COC(=N)N1CCCC1,,CO,,C[O-].[Na+],,test
US20070185143A1,CC(C)(C)OC(=O)N[C@](C)(C(=O)N1CCOCC1)c1ccccc1.Cl>>C[C@@](N)(C(=O)N1CCOCC1)c1ccccc1.Cl,,C1COCCO1,,,,test
US20130150343A1,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1.N[C@H]1CC[C@@H](Oc2ccc3nnc(N4CCCOCC4)n3c2)c2ccccc21>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCCOCC5)n4c3)c3ccccc32)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20150065705A1,O=c1nc(N2CCC(O)(c3ccc(F)cc3)C(O)C2)ncn1Cc1ccc(Cl)cc1>>O=C1CN(c2ncn(Cc3ccc(Cl)cc3)c(=O)n2)CCC1c1ccc(F)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20160185778A1,CCC=Cc1nn(Cc2ccc(OC)cc2)c2c1CN(C(=O)OC(C)(C)C)CC2>>CCC=Cc1n[nH]c2c1CNCC2,,O=C(O)C(F)(F)F,,,,test
US20060094767A1,C[C@@]1(Cn2cc([N+](=O)[O-])nc2Cl)CO1.O=c1[nH]nc(-c2ccc(OC(F)(F)F)cc2)o1>>C[C@@](O)(Cn1cc([N+](=O)[O-])nc1Cl)Cn1nc(-c2ccc(OC(F)(F)F)cc2)oc1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120283238A1,Clc1ccnc2sccc12.OC1CCC(N2CCOCC2)CC1>>c1cc(OC2CCC(N3CCOCC3)CC2)c2ccsc2n1,,CN(C)C=O,,[H-].[Na+],,test
US20070275907A1,CN(C)Cl.Cc1ccc(S(=O)(=O)OC[C@H]2O[C@]3(OCc4cc(Cl)c(Cc5ccc(C(C)C)cc5)cc43)[C@H](O)[C@@H](O)[C@@H]2O)cc1>>CC(C)c1ccc(Cc2cc3c(cc2Cl)CO[C@]32O[C@H](CN(C)C)[C@@H](O)[C@H](O)[C@H]2O)cc1,,CN(C)C=O,O,CCN(CC)CC,,test
US20160122339A1,C1COCCN1.O=C(Cl)c1cnc2ccc(Br)cc2c1Cl>>O=C(c1cnc2ccc(Br)cc2c1Cl)N1CCOCC1,,ClCCl,,CCN(CC)CC,,test
US20120277224A1,CC1(C)OC(=O)C(C(=O)c2ccc(S(C)(=O)=O)cc2)C(=O)O1.CCO>>CCOC(=O)CC(=O)c1ccc(S(C)(=O)=O)cc1,,CCO,,,,test
US20040198786A1,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].Cc1oc(-c2ccc(F)cc2)nc1CO[C@@H]1CCC[C@H](OC(=O)c2cccc(C#N)c2)C1>>Cc1oc(-c2ccc(F)cc2)nc1CO[C@@H]1CCC[C@H](OC(=O)c2cccc(-c3nnn[nH]3)c2)C1,,Cc1ccccc1C,,,,test
US05712267,COc1ccc(CS[C@H]2C[C@@H](C(=O)O)N(C)C2)cc1.OCCN1CCNCC1>>COc1ccc(CS[C@H]2C[C@@H](C(=O)N3CCN(CCO)CC3)N(C)C2)cc1,,CC#N,,,,test
US20110251190A1,CO.NC1=N[C@@]2(CO1)c1cc(-c3cccnc3)ccc1Oc1c2cc(-c2cccnc2)nc1F>>COc1nc(-c2cccnc2)cc2c1Oc1ccc(-c3cccnc3)cc1[C@@]21COC(N)=N1,,CO,,C[O-].[Na+],,test
US04881965,Cc1ccn(-c2ccccn2)n1.O=S(=O)(O)Cl>>Cc1nn(-c2ccccn2)cc1S(=O)(=O)Cl,,ClC(Cl)Cl,,,,test
US20140288081A1,CCOC(=O)c1ccc(NS(=O)(=O)c2ccc(F)c(N)c2N)cc1>>Nc1c(F)ccc(S(=O)(=O)Nc2ccc(C(=O)O)cc2)c1N,,CCO,O,[Li]O,,test
US20140051708A1,CCOC(=O)c1cc(C(C)=O)[nH]n1.CI>>CCOC(=O)c1cc(C(C)=O)nn1C,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4cccc(S(C)(=O)=O)c4)nc(Cl)c3n2)cc1.COc1ccc(N)cc1OC>>COc1ccc(Nc2nc(-c3cccc(S(C)(=O)=O)c3)nc3cn[nH]c23)cc1OC,C1COCCO1,CO,,Cl,,test
US06245742B1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)OCc1ccccc1.CCOP(=O)(Cl)OCC>>CCOP(=O)(OCC)Oc1ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2)cc1,,C1COCCO1,,[H-].[Na+],,test
US06172064B2,CC(C)(C)OC(=O)N[C@H](C(=O)O)C(C)(C)C.NCc1ccccn1>>CC(C)(C)OC(=O)N[C@H](C(=O)NCc1ccccn1)C(C)(C)C,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20110311458A1,Cc1ccccc1C(=O)CBr.O=C(O[C@H]1CN2CCC1CC2)[C@H](Nc1ccccc1)c1ccccc1>>Cc1ccccc1C(=O)C[N+]12CCC(CC1)[C@@H](OC(=O)[C@H](Nc1ccccc1)c1ccccc1)C2.[Br-],,CCOC(C)=O,,,,test
US20140322229A1,CCOC(=O)c1cc2ccccc2n1CC(=O)O.C[NH3+]>>CCOC(=O)c1cc2ccccc2n1CC(=O)NC,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160272588A1,CCc1c(-c2ccc(O)cc2)cnc(N)c1-c1ccc2c(cnn2C(=O)OC(C)(C)C)c1>>CCc1c(-c2ccc(O)cc2)cnc(N)c1-c1ccc2[nH]ncc2c1,,CCOC(C)=O,,Cl,,test
US20150274704A1,CC(C)(C)OC(=O)N1CC(N)C2(CCCC2)C1.Cc1cnc(Cl)nc1Cl>>Cc1cnc(Cl)nc1NC1CN(C(=O)OC(C)(C)C)CC12CCCC2,,CCO,,CCN(CC)CC,,test
US20100081679A1,CC(C)N.O=C(Cl)c1ccc(Nc2ncc(Cl)c(NC3CC3)n2)cc1>>CC(C)NC(=O)c1ccc(Nc2ncc(Cl)c(NC3CC3)n2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04209525,CCOC(=O)CC(=O)OCC=N.NC(=O)C(N)C(N)=O>>CCOC(=O)Cc1nc(C(N)=O)c(O)[nH]1,,CO,,Cl,,test
US20110136763A1,CCOC(=O)CC1OB(O)c2cc(Oc3nnc(C#N)s3)cc(C)c21.NO>>CCOC(=O)CC1OB(O)c2cc(Oc3nnc(C(=N)NO)s3)cc(C)c21,,CO,,CCN(CC)CC,Cl,test
US04126624,COC1=CC(OC)OC1(OC)C(C)O>>Cc1occc(=O)c1O,,O=S(=O)(O)O,,,,test
US07067658B2,CC[C@H](COC)Nc1nccc(Cl)c1[N+](=O)[O-]>>CC[C@H](COC)Nc1nccc(Cl)c1N,,CCOCC,Cl,Cl[Sn]Cl,,test
US20140045862A1,CCn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)N(Cc2ccc(OC)cc2OC)c2ccncn2)cc1F>>CCn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US04507306,C=CC#N.Cl.c1ccc([C@]23CCNC[C@H]2c2ccccc2O3)cc1>>Cl.N#CCCN1CC[C@]2(c3ccccc3)Oc3ccccc3[C@@H]2C1,,CCOCC,,,,test
US20150232465A1,CC(=O)Nc1ccc(Br)nc1N(Cc1ccccc1)C[C@@H](C)O>>CC(=O)N1c2ccc(Br)nc2N(Cc2ccccc2)C[C@@H]1C,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130345120A1,CN(C)C(=O)C1CC=NN1C(=O)[C@@H](CC(=O)OC(C)(C)C)CC1CCCC1>>CN(C)C(=O)C1CC=NN1C(=O)[C@@H](CC(=O)O)CC1CCCC1,,C1COCCO1,,Cl,,test
US20130116248A1,CI.Cn1c(=NC#N)n(-c2ccc(C(C)(C)C#N)cc2)c2c3cc(-c4cnc(N)c(C(F)(F)F)c4)ccc3ncc21>>CNc1ncc(-c2ccc3ncc4c(c3c2)n(-c2ccc(C(C)(C)C#N)cc2)c(=NC#N)n4C)cc1C(F)(F)F,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20150266837A1,CC(C)(C)OC(=O)NCCCN(N)C#N.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)NCCCN(N)c1nnn[nH]1,,CN(C)C=O,,[Cl-].[NH4+],,test
US20100099665A1,Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC(C)(C)CO[Si](C)(C)C(C)(C)C)cc(SC3CCN(C(=O)OC(C)(C)C)CC3)c2c1.O=C(OO)c1cccc(Cl)c1>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC(C)(C)CO[Si](C)(C)C(C)(C)C)cc(S(=O)C3CCN(C(=O)OC(C)(C)C)CC3)c2c1,,ClCCl,,,,test
US20050059668A1,CC(C)(C)OC(=O)N1CCN(c2ccc(C(F)(F)F)cc2F)CC1>>Fc1cc(C(F)(F)F)ccc1N1CCNCC1,,C1COCCO1,,Cl,,test
US20080214594A1,CCOC(=O)Cl.Nc1cc2ccccc2cc1C(=O)O>>CCOc1nc2cc3ccccc3cc2c(=O)o1,,c1ccncc1,,,,test
US20160214971A1,COc1cccc(CS)c1.Cc1cc(C(=O)NS(C)(=O)=O)c(F)cc1-c1cnc(F)c(Cl)c1>>COc1cccc(CSc2ncc(-c3cc(F)c(C(=O)NS(C)(=O)=O)cc3C)cc2Cl)c1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06057369,COc1ccc(S[C@@H](CCCCc2ccccc2)[C@H](C)C(=O)O)cc1OC.C[Si](C)(C)ON>>COc1ccc(S[C@@H](CCCCc2ccccc2)[C@H](C)C(=O)NO)cc1OC,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US04568741,O=CN1CCCCC1.O=S(Cl)Cl>>ClC=[N+]1CCOCC1.[Cl-],,Cc1ccccc1,,ClCCl,,test
US20110124904A1,CC(=O)OCCCC=O>>CC(=O)OCCCCO,,C1CCOC1,,,,test
US20090214441A1,CCCCCCCC/C=C\CCCCCCCCN>>CCCCCCCCCCCCCCCCCCN,[Pd],CCO,,[H][H],,test
US20070142448A1,CO.Cc1nc2c(OCc3ccccc3)cc(C(=O)O)cc2[nH]1>>COC(=O)c1cc(OCc2ccccc2)c2nc(C)[nH]c2c1,,CCOC(C)=O,,O=S(Cl)Cl,,test
US20110312945A1,CC(=O)CC1CCCCC1=O.CCOC(=O)CN>>CCOC(=O)Cn1c(C)cc2c1CCCC2,,ClCCl,,Cl,O=C([O-])O.[Na+],test
US04112095,CC(=O)NN.Clc1ccc(-c2ccc(Cl)c(Cl)c2)nn1>>Cc1nnc2ccc(-c3ccc(Cl)c(Cl)c3)nn12,,CCCCO,,,,test
US04283341,CC(=O)CC(=O)O[C@H](C=C(C)C)C(Cl)(Cl)Cl.Cc1ccc(S(=O)(=O)N=[N+]=[N-])cc1>>CC(C)=C[C@@H](OC(=O)C=[N+]=[N-])C(Cl)(Cl)Cl,,CC#N,,CCN(CC)CC,[Na+].[OH-],test
US20060128734A1,CN(C)Cc1cc(N)cc(C(F)(F)F)c1.O=C=Nc1ccc(Oc2cc(Cl)ncn2)cc1>>CN(C)Cc1cc(NC(=O)Nc2ccc(Oc3cc(Cl)ncn3)cc2)cc(C(F)(F)F)c1,,C1CCOC1,CCOCC,,,test
US20100056566A1,Brc1ccc2cnccc2c1.COC(=O)[C@@H]1C[C@@H](N)CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1C[C@@H](Nc2ccc3cnccc3c2)CN1C(=O)OC(C)(C)C,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20070265272A1,Brc1cnc2nnn(Cc3ccc4c(c3)CCO4)c2n1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cn1cc(-c2cnc3nnn(Cc4ccc5c(c4)CCO5)c3n2)cn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,N#N,O=C([O-])[O-].[Na+].[Na+],test
US05292732,CC(=O)NCCn1ccc2c1-c1cc(Cl)ccc1CC2.O=C(O)/C=C/C(=O)O>>CC1=NCCn2c1cc1c2-c2cc(Cl)ccc2CC1.O=C(O)/C=C/C(=O)O,,CCO,,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US20070135456A1,C=CCn1c(Cl)nc2[nH]c(=O)[nH]c(=O)c21.FCCCCBr>>C=CCn1c(Cl)nc2c1c(=O)[nH]c(=O)n2CCCCF,,CO,CS(C)=O,O=C([O-])O.[Na+],,test
US20140275016A1,CCC(=O)Nc1cc(Oc2ccc([N+](=O)[O-])nc2)ccn1>>CCC(=O)Nc1cc(Oc2ccc(N)nc2)ccn1,[Zn],C1CCOC1,CO,[Cl-].[NH4+],,test
US08350090B1,O=C(O)Cc1cccc(OCc2ccccc2)c1.c1ccoc1>>O=C(Cc1cccc(OCc2ccccc2)c1)c1ccco1,,ClCCl,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US20020065308A1,CCOP(=O)(CC(O)Cc1ccc(F)c(C)c1)OCC>>CCOP(=O)(CC(=O)Cc1ccc(F)c(C)c1)OCC,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20050148631A1,CC(=O)Nc1nc(C)c(S(=O)(=O)Nc2cccc(C)n2)s1>>Cc1cccc(NS(=O)(=O)c2sc(N)nc2C)n1,,CCO,,Cl,,test
US20150239847A1,Nc1ccn(-c2ccccc2Cl)n1.O=C1CCC(=O)N1I>>Nc1nn(-c2ccccc2Cl)cc1I,,C1CCOC1,,,,test
US05811459,BrCc1ccccc1.CC(C)(C)C(=O)Oc1ccc(O)c(CCCc2ccc(C(=O)O)cc2)c1>>O=C(O)c1ccc(CCCc2cc(O)ccc2OCc2ccccc2)cc1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US04587241,C=CCc1ncc(CO)n1OC(C)=O.ClCCl.O=S(Cl)Cl>>C=CCc1ncc(CCl)n1OC(C)=O.Cl,,ClCCl,,,,test
US20150038438A1,COc1ccc(CN)c(OC)c1.Cn1c(CO[Si](C)(C)C(C)(C)C)cc2c3c(ccc21)C(=O)CCCC3>>COc1ccc(CN=C2CCCCc3c2ccc2c3cc(CO[Si](C)(C)C(C)(C)C)n2C)c(OC)c1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,CCN(CC)CC,,test
US20040209895A1,CC(C)(C)NC(=O)c1cnc(Cl)nc1Cl.NCCCNS(=O)(=O)c1cccc([N+](=O)[O-])c1>>CC(C)(C)NC(=O)c1cnc(Cl)nc1NCCCNS(=O)(=O)c1cccc([N+](=O)[O-])c1,,C1CCOC1,,CCN(CC)CC,,test
US04178293,CS(=O)(=O)Cl.N#CC(O)c1cccc(Oc2ccccc2)c1>>CS(=O)(=O)OC(C#N)c1cccc(Oc2ccccc2)c1,,CCOCC,,CCN(CC)CC,O,test
US20060025601A1,COc1ccc2c(c1)CCC2=O.O=C1CCC(=O)N1Br>>COc1ccc2c(c1)C(Br)CC2=O,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US07019019B2,CC(C)(C)OC(=O)C=C[C@@](Cc1cccc(C#N)c1)(NC(=O)OC(C)(C)C)C(=O)O.CN(C)C(On1nnc2cccnc21)=[N+](C)C.CO.ClCCl.N#Cc1ccc(CNC(=O)CN)s1>>COC(=O)C(CCSC)N=Cc1ccc(Cl)cc1,,CC#N,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20020165282A1,CCCCCCCN(CCc1ccc(CC(OCC)C(=O)OC)cc1)C(=O)C1(c2ccc(C)cc2)CC1>>CCCCCCCN(CCc1ccc(CC(OCC)C(=O)O)cc1)C(=O)C1(c2ccc(C)cc2)CC1,,C1CCOC1,,[Li+].[OH-],,test
US05470967,Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O>>Cc1cn([C@H]2C[C@H](N)[C@@H](CO)O2)c(=O)[nH]c1=O,[Pd],CCO,,[H][H],,test
US05236948,CNc1ccc(C)cc1.CS(=O)(=O)Cl>>CNS(=O)(=O)Cc1ccc(C)cc1,,ClCCl,,CCN(CC)CC,,test
US20090281097A1,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C(C(=O)N2CCOCC2)C1>>O=C(C1CNCCN1C(=O)OCc1ccccc1)N1CCOCC1,,CCOC(C)=O,Cl,,,test
US20090247519A1,CC(=O)OC(C)=O.Oc1ccc(O)c(-c2nc(Cl)c3ccccc3n2)c1>>CC(=O)Oc1ccc(O)c(-c2nc(Cl)c3ccccc3n2)c1,,ClCCl,,c1ccncc1,,test
US20150191476A1,c1cc(C2CC2)cc(C2OCCO2)c1>>O=Cc1cccc(C2CC2)c1,,C1CCOC1,,Cl,,test
US20160221972A1,COC(=O)c1ccc2c(c1)OC[C@H](C)NC2.COC1CCNCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COC(=O)c1ccc2c(c1)OC[C@H](C)N(C(=O)N1CCC(OC)CC1)C2,,ClCCl,O,CCN(CC)CC,,test
US20030212170A1,C1CCNCC1.CC(C)(C)c1ccc(O)c(C(C)(C)C)c1.O=Cc1ccc(C(F)(F)F)cc1>>CC(C)(C)c1cc(C(c2ccc(C(F)(F)F)cc2)N2CCCCC2)c(O)c(C(C)(C)C)c1,,Cc1ccccc1,,,,test
US20150011532A1,COC(=O)c1nnc(-c2cnc(Nc3ccc4ncsc4c3)cc2NC(C)C)o1>>CC(C)Nc1cc(Nc2ccc3ncsc3c2)ncc1-c1nnc(CO)o1,,C1CCOC1,CCOC(C)=O,CO,[BH4-].[Li+],test
US05225402,CC(=O)O.COC1CCC(OC)O1.NCCCCOc1ccc(C(=O)N2CCC(N3C(=O)CCc4ccccc43)CC2)cc1>>O=C(c1ccc(OCCCCn2cccc2)cc1)N1CCC(N2C(=O)CCc3ccccc32)CC1,,CC(=O)O,,,,test
US20160200695A1,COc1ccc2nc(NC(=O)c3ccc([C@H](N[S@@](=O)C(C)(C)C)c4ccccc4)cc3)sc2c1>>COc1ccc2nc(NC(=O)c3ccc([C@H](N)c4ccccc4)cc3)sc2c1,,CO,,Cl,,test
US06051732,CC(=O)Oc1cccc(C(=O)Cl)c1C.Nc1cc(S(=O)(=O)O)c2cccc(S(=O)(=O)O)c2c1>>Cc1c(O)cccc1C(=O)O,,O,,,,test
US20080227770A1,CCOC(=O)Cc1cnc(C[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3N(CC(C)(C)COC(C)=O)C2=O)s1>>COc1cccc([C@H]2O[C@H](Cc3ncc(CC(=O)O)s3)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC,,O,,CCO,[Na+].[OH-],test
US20060079504A1,CN1CC2CC1CN2C1CCNCC1.Nc1c(Cl)cc(C[C@@H](CC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)O)cc1C(F)(F)F>>CN1CC2CC1CN2C1CCN(C(=O)[C@H](CC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)Cc2cc(Cl)c(N)c(C(F)(F)F)c2)CC1,,CCN(CC)CC,,,,test
US20080108608A1,Nc1ncc(Br)s1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ncc(Br)s1)Oc1ccccc1,,ClCCl,,c1ccncc1,,test
US20100234312A1,COC(=O)CBr.Cc1n[nH]c(=O)n1C>>COC(=O)Cn1nc(C)n(C)c1=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20020032180A1,CCCCCC.C[C@]12CC[C@@H]3[C@H]4CCC(=O)C=C4C=C[C@H]3[C@@H]1CCC2=O>>CC[C@H]1CC2=CC(=O)CC[C@@H]2[C@H]2CC[C@]3(C)C(=O)CC[C@H]3[C@H]12,,C1CCOC1,,CCOC(C)=O,[Cl-].[NH4+],test
US20080045555A1,CC(C)Cn1c(=O)n2cnnc2c2nc[nH]c21.O=C1CCC(=O)N1Br>>CC(C)Cn1c(=O)n2cnnc2c2nc(Br)[nH]c21,,C1CCOC1,,,,test
US20090325952A1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1ccccc1NC(=O)OC(C)(C)C>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1ccccc1N,,C1COCCO1,CO,Cl,,test
US20150259354A1,N#Cc1c(-c2ccc(Oc3ccccc3)cc2)nn2c(-c3cccc(N)c3)ccnc12>>N#Cc1c(-c2ccc(Oc3ccccc3)cc2)nn2c1NCCC2c1cccc(N)c1,,CCO,,[BH4-].[Na+],,test
US20110311474A1,CC[C@@H]1C[C@@H](Oc2ccc(C#N)cc2)C[C@@H]1c1nnc2cnc3c(ccn3S(=O)(=O)c3ccc(C)cc3)n12>>CC[C@@H]1C[C@@H](Oc2ccc(C#N)cc2)C[C@@H]1c1nnc2cnc3[nH]ccc3n12,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20150344423A1,COC(=O)c1cc(C=C2CCCCC2)n(-c2cc(C)cc(C(C)(C)C)c2)n1>>COC(=O)c1cc(CC2CCCCC2)n(-c2cc(C)cc(C(C)(C)C)c2)n1,[Pd],CO,,,,test
US20080262042A1,CN(Cc1cn(S(=O)(=O)c2ccc(O)cc2)c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C.Cl>>CNCc1cn(S(=O)(=O)c2ccc(O)cc2)c(-c2cccnc2F)c1F.Cl,,CCO,,CCOC(C)=O,,test
US20090221586A1,CCI.COc1ccc(-c2nc(CCC(=O)c3ncccc3C)co2)cc1O>>CCOc1cc(-c2nc(CCC(=O)c3ncccc3C)co2)ccc1OC,,CCO,CCOC(C)=O,C1CCC2=NCCCN2CC1,O,test
US20150274733A1,CC1CC(=O)CN1C(=O)OC(C)(C)C.COC(OC)N(C)C>>CC1/C(=C/N(C)C)C(=O)CN1C(=O)OC(C)(C)C,,CCOC(C)=O,,,,test
US20130018049A1,COC(=O)c1c(C)nc(N)c(CO)c1-c1ccc2c(c1)CCCO2>>COC(=O)c1c(C)nc(N)c(C=O)c1-c1ccc2c(c1)CCCO2,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US04115575,CC(C)NCC(O)COc1ccc(CCN)cn1.COC(=O)Cl>>COC(=O)NCCc1ccc(OCC(O)CNC(C)C)nc1,,CC(C)O,O,,,test
US20090082362A1,CC(C)Cc1ccc(N)cc1.O=C(Cl)Oc1ccccc1>>CCC(C)c1ccc(NC(=O)Oc2ccccc2)cc1,,c1ccncc1,,CCCCCC,CCOC(C)=O,test
US20120196864A1,CCN1C(=N)/C(=C/c2ccc(OCc3ccccc3C(F)(F)F)c(OC)c2)N(C)C1=O.CI>>CCN1C(=O)N(C)C(=C\c2ccc(OCc3ccccc3C(F)(F)F)c(OC)c2)/C1=N\C,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04935442,CC(C)(C)CC(C)(C)c1ccc(OCc2ccccc2)c(OCC2(C)CCC(CO)O2)c1>>CC(C)(C)CC(C)(C)c1ccc(O)c(OCC2(C)CCC(CO)O2)c1,[Pd],CCO,,,,test
US04818270,CCOC(=O)c1oc(Cl)nc1C(F)(F)F.c1ccc2[nH]cnc2c1>>CCOC(=O)c1oc(-n2cnc3ccccc32)nc1C(F)(F)F,,CCOCC,,,,test
US20120271048A1,CS(=O)c1nccc(-n2ccc3ccc(-c4cccc([N+](=O)[O-])c4)cc32)n1.N>>Nc1nccc(-n2ccc3ccc(-c4cccc([N+](=O)[O-])c4)cc32)n1,,CC(C)O,,O,,test
US05387594,CC1(C)CCC(C)(C)c2cc(C(=O)C(=O)Cl)ccc21.COC(=O)c1ccc(N)cc1O>>COC(=O)c1ccc(NC(=O)C(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1O,,C1CCOC1,,O,c1ccncc1,test
US20140018313A1,CC(C)(C)OC(=O)N1CCC[C@H]1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1.COC(=O)N[C@H](C(=O)N1C[C@@H](O)C[C@H]1c1ncc(-c2ccc3cc(Br)ccc3c2)[nH]1)C(C)C>>COC(=O)N[C@H](C(=O)N1C[C@@H](O)C[C@H]1c1ncc(-c2ccc3cc(-c4ccc(-c5cnc([C@@H]6CCCN6C(=O)OC(C)(C)C)[nH]5)cc4)ccc3c2)[nH]1)C(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20130131018A1,CC(C)(C)O.CCOc1ccc2c(Cc3cc(OC)c(OC)c(OC)c3)cncc2c1N.O=C=NS(=O)(=O)Cl>>CCOc1ccc2c(Cc3cc(OC)c(OC)c(OC)c3)cncc2c1NS(=O)(=O)NC(=O)OC(C)(C)C,,C1CCOC1,,,,test
US20090088431A1,Nc1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nc1.O=C(O)CCCc1ccccc1>>O=C(CCCc1ccccc1)Nc1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090099156A1,CCN1CCN(C(=O)OC(C)(C)C)[C@@H](C(=O)N2CCNCC2)C1.O=C=Nc1ccc(Cl)cc1>>CCN1CCN[C@@H](C(=O)N2CCN(C(=O)Nc3ccc(Cl)cc3)CC2)C1,,ClCCl,,CCN(CC)CC,CO,test
US20120129870A1,Cc1cc([N+](=O)[O-])ccc1N1CCN(C(c2ccccc2)c2ncco2)CC1>>Cc1cc(N)ccc1N1CCN(C(c2ccccc2)c2ncco2)CC1,[Pd],CCO,,[H][H],,test
US20130172550A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.O=[N+]([O-])c1c(O)ccc2c1CCC2.O=[N+]([O-])c1cc2c(cc1O)CCC2>>O=[N+]([O-])c1c(OS(=O)(=O)C(F)(F)F)ccc2c1CCC2.O=[N+]([O-])c1cc2c(cc1OS(=O)(=O)C(F)(F)F)CCC2,,ClCCl,,CCN(CC)CC,,test
US20130324576A1,CC(C)(C)OC(=O)N1CCC(C(O)c2ccc(Cl)cc2)CC1.Cl>>Cl.OC(c1ccc(Cl)cc1)C1CCNCC1,,CO,,,,test
US06143764,CCCCN=C=O.COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC>>CCCCNC(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1,,Cc1ccccc1,,,,test
US20160272651A1,Cc1cc(N(CCO)C(=O)c2c(Cl)ncnc2Cl)cc(C)c1-n1c(=O)n(CC(F)(F)F)c2ccccc21>>Cc1cc(N2CCOc3ncnc(Cl)c3C2=O)cc(C)c1-n1c(=O)n(CC(F)(F)F)c2ccccc21,,CC#N,,O=C([O-])O.[Na+],,test
US20090143358A1,C1CCOC1.C=Cc1cc(C(=O)OCC)ccc1F>>O=C(O)c1ccc(F)c(C2CC2)c1,,O,,[Li+].[OH-],,test
US20010047031A1,BrCc1ccccc1.CC(C)(C)OC(=O)N1CC(O)C(Sc2ccc(O)cc2)C1>>CC(C)(C)OC(=O)N1CC(O)C(Sc2ccc(OCc3ccccc3)cc2)C1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050222118A1,COC[C@H](CCN1CC(Oc2ccc(Cl)cc2)C1)NC(=O)OC(C)(C)C>>COC[C@@H](N)CCN1CC(Oc2ccc(Cl)cc2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050267093A1,C[Si](C)(C)C#Cc1ccc(CN2CCCC2)cc1>>C#Cc1ccc(CN2CCCC2)cc1,,CO,ClCCl,[Na+].[OH-],,test
US20060223794A1,Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1.O=C(O)/C=C/C(=O)O>>Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1.O=C([O-])/C=C/C(=O)[O-],,CO,,CC(C)=O,,test
US20150329523A1,COc1cc(N)cc(OCCOCCOCCO)c1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c(Cl)c2Cl)cc1>>COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)nn4-c4ccc(C)cc4)c(Cl)c3Cl)n2)cc(OCCOCCOCCO)c1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US05225414,CCCCc1nc(Cl)c(C=O)n1Cc1ccc(-c2nc3ccccn3c2C(=O)OCC)cc1>>CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2nc3ccccn3c2C(=O)O)cc1,,CCO,,[BH4-].[Na+],,test
US20150299189A1,CC(C)(C)OC(=O)c1cc(C2CC2)cnc1Nc1cccc2c1ccn2CC1CCOCC1>>O=C(O)c1cc(C2CC2)cnc1Nc1cccc2c1ccn2CC1CCOCC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US05665718,CCCBr.CCN(C(C)C)C(C)C.CN(C)C=O.NCc1nc(-c2ncn3c2[C@@H]2CCN2C(=O)c2sccc2-3)no1>>CCCN(CCC)Cc1nc(-c2ncn3c2[C@@H]2CCN2C(=O)c2sccc2-3)no1,,CN(C)C=O,,,,test
US20090149445A1,CC(Cn1c(=O)[nH]c2cc(B3OC(C)(C)C(C)(C)O3)ccc21)N1CCOCC1.Fc1ccc2c(c1)CCc1cc(F)ccc1C2=CBr>>O=c1[nH]c2cc(C=C3c4ccc(F)cc4CCc4cc(F)ccc43)ccc2n1CCCN1CCOCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20150166480A1,CC(C)(C)OC(=O)N1CCC(COc2cnc(I)cn2)CC1.Cl>>Cl.Ic1cnc(OCC2CCNCC2)cn1,,ClCCl,,C1COCCO1,,test
US20100125061A1,CC(=O)Oc1c(C)c(CC(=O)OC(C)(C)C)cc2ccc(F)cc12>>Cc1c(CC(=O)OC(C)(C)C)cc2ccc(F)cc2c1O,,CO,,Cl,C[O-].[Na+],test
US20160090377A1,C1=COCCC1.CC1=C(c2ccc(F)cc2)C(c2ccc(I)cc2)Oc2cc(O)ccc21>>CC1=C(c2ccc(F)cc2)C(c2ccc(I)cc2)Oc2cc(OC3CCCCO3)ccc21,,ClCCl,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20100179148A1,C1COCCO1.CN1CCN(CCCO)CC1.Cl.O=C(Cl)OC(Cl)(Cl)Cl>>CCCN1CCN(C)CC1.CCOC(=O)Cl.Cl.Cl,,C1COCCO1,CC#N,,,test
US20050282812A1,CCC(CO)Nc1ccc(C(F)(F)F)cc1[N+](=O)[O-].CS(=O)(=O)Cl>>CCC(COS(C)(=O)=O)Nc1ccc(C(F)(F)F)cc1[N+](=O)[O-],,ClCCl,,c1ccncc1,,test
US20110028487A1,CC1CCNCC1.O=C(Cl)CCl>>CC1CCN(C(=O)CCl)CC1,,CCOCC,ClCCl,CCN(CC)CC,,test
US06649643B1,COc1cc2ccc(C(O)(c3cn(COCc4ccccc4)cn3)C(C)C)cc2cc1OC>>COc1cc2ccc([C@](O)(c3c[nH]cn3)C(C)C)cc2cc1OC,[Pd],CO,,CC(=O)O,,test
US20090149456A1,CN(C)CCOc1cccc(N)c1.COc1ccc2c(-c3ccnc(Cl)n3)c(-c3cccc(NC(=O)C(F)(F)F)c3)nn2c1>>COc1ccc2c(-c3ccnc(Nc4cccc(OCCN(C)C)c4)n3)c(-c3cccc(NC(=O)C(F)(F)F)c3)nn2c1,,CC(C)O,,Cl,Cl,test
US20060235029A1,Cc1ccc(C(=O)O)cc1-c1nc(N2CCC(N3CCC(C)CC3)CC2)nc2c1ccc(=O)n2-c1c(F)cccc1F.NCC1CC1>>Cc1ccc(C(=O)NCC2CC2)cc1-c1nc(N2CCC(N3CCC(C)CC3)CC2)nc2c1ccc(=O)n2-c1c(F)cccc1F,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100179173A1,CC(C)(C)OC(=O)N1CCc2nc(N)nc(O)c2C1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)Oc2nc(N)nc3c2CN(C(=O)OC(C)(C)C)CC3)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US05179107,BrCc1ccccc1.O=c1[nH]c2ccccc2c(=O)o1>>O=C1NC2C=CC=CC2(Cc2ccccc2)C(=O)O1,,CN(C)C=O,,[H][H],[H-].[Na+],test
US06060508,CCN(CC)C(CO)c1cccc2c(C)c(C)oc12.Cl>>CCN(CC)C(CO)c1cccc2c(C)c(C)oc12.Cl,,CC(C)O,,,,test
US20080227770A1,CCOC(=O)CBr.COc1cccc([C@H]2O[C@H](CC(=O)c3ccc(O)cc3)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC>>COc1cccc([C@H]2O[C@H](CC(=O)c3ccc(OCC(=O)O)cc3)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20130244958A1,CC(Cl)OC(=O)Cl.COCCOCCOCCO>>COCCOCCOCCOC(=O)OC(C)Cl,,ClCCl,,c1ccncc1,,test
US20140288084A1,Fc1cc(Br)ccc1CBr.O=C1NCc2ncccc21>>O=C1c2cccnc2CN1Cc1ccc(Br)cc1F,,CN(C)C=O,,O,[H-].[Na+],test
US20130274255A1,C[Si](C)(C)CCOCn1nc(-c2ccc(Nc3cccc(O)c3)cc2)c2c1-c1ccsc1C2>>Oc1cccc(Nc2ccc(-c3n[nH]c4c3Cc3sccc3-4)cc2)c1,,CO,,Cl,,test
US20060074056A1,Cn1cnc(-c2cc3nccc(Oc4ccc(N)cc4)c3s2)c1.O=C(Cc1ccccc1)N=C=S>>Cn1cnc(-c2cc3nccc(Oc4ccc(NC(=S)NC(=O)Cc5ccccc5)cc4)c3s2)c1,,C1CCOC1,,,,test
US05466698,C#CCCN1CC=C(c2ccccc2)CC1.O=[N+]([O-])c1ccc(Br)nc1>>O=[N+]([O-])c1ccc(C#CCCN2CC=C(c3ccccc3)CC2)nc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,CCN(CC)CC,,,test
US04038311,Cc1ccccc1N=C1CCCCC1.O=C(Cl)Cl>>Cc1ccccc1N(C(=O)Cl)C1=CCCCC1,,CCOCC,,CCN(CC)CC,,test
US20110226999A1,O=C(Cl)c1cc(-c2cccs2)c(C(=O)Cl)cc1-c1cccs1>>O=c1c2cc3c(cc2c2sccc12)c(=O)c1ccsc13,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US06001856,CC(=O)Nc1ccc([C@@H](O)COS(=O)(=O)c2ccc(C)cc2)cn1>>CC(=O)Nc1ccc([C@@H]2CO2)cn1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US07375227B2,CNc1cc(C)nc2ccccc12.NCCN1CCC(Cc2ccccc2)CC1.O=C(n1ccnc1)n1ccnc1>>Cc1cc(N(C)C(=O)NCCN2CCC(Cc3ccccc3)CC2)c2ccccc2n1,,CS(C)=O,O,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20090030195A1,C1CCNCC1.CS(=O)(=O)OC[C@H]1CN(c2ccc3cc(-c4ccccc4C(F)(F)F)[nH]c(=O)c3c2)C(=O)O1>>O=C1O[C@@H](CN2CCCCC2)CN1c1ccc2cc(-c3ccccc3C(F)(F)F)[nH]c(=O)c2c1,,CC#N,,,,test
US20130053365A1,COC(=O)c1cc(F)cc([N+](=O)[O-])c1C(=O)Cc1ncnn1C>>COC(=O)c1cc(F)cc(N)c1C(=O)Cc1ncnn1C,[Zn],CO,,O=C[O-].[NH4+],,test
US04474797,CS(=O)(=O)Cl.Cn1nc(Cl)c(Cl)c1SCCO>>Cn1nc(Cl)c(Cl)c1SCCOS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20130345174A1,O=C(O)c1cccc(-c2ccccc2)n1.O=S(Cl)Cl>>O=C(Cl)c1cccc(-c2ccccc2)n1,,Cc1ccccc1,,,,test
US04863942,CCCc1c(OCCCOc2cccc([N+](=O)[O-])c2)ccc(C(C)=O)c1OC>>CCCc1c(OCCCOc2cccc(N)c2)ccc(C(C)=O)c1OC,[Ni],C1CCOC1,,,,test
US20090043096A1,CC(=O)OC=Cc1ccccc1.Cc1ccccc1.Cc1cccnc1-c1ccccc1>>Cc1cccc(-c2c(C)cccc2/C=C/c2ccccc2)n1,,CCCCCC,CCOC(C)=O,CCN(CC)CC,,test
US04265890,BrBr.COc1cc2c(cc1OC)CCNCC2>>COc1cc2c(c(Br)c1OC)CCNCC2,,CC(=O)O,,[Na+].[OH-],,test
US20130158003A1,Cc1nc2ccccc2nc1CCC(=O)O.Nc1ccccc1N>>Cc1nc2ccccc2nc1CCc1nc2ccccc2[nH]1,,C1COCCO1,Cl,O=C([O-])[O-].[Na+].[Na+],,test
US20100240671A1,CON(C)C(=O)Cc1ccc(-c2ccccc2)cc1.c1cscn1>>O=C(Cc1ccc(-c2ccccc2)cc1)c1nccs1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20060264460A1,COc1ncccc1C=O.N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1>>COc1ncccc1CNc1ccc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1,,CCO,,[BH3-]C#N.[Na+],,test
US20140275087A1,Cn1cnc(S(=O)(=O)N2C[C@@H](O)[C@H](c3ccc(F)cc3)C2)c1>>Cn1cnc(S(=O)(=O)N2CC(=O)C(c3ccc(F)cc3)C2)c1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20040157904A1,BrBr.Cc1ccccc1-n1nc(C(C)(C)C)cc1N>>Cc1ccccc1-n1nc(C(C)(C)C)c(Br)c1N,,CC(=O)O,O,,,test
US20070270385A1,CC(C)(C)OC(=O)NC[C@@H](O)CP(=O)(O)CC1CCCCC1.Oc1ccccc1>>CC(C)(C)OC(=O)NC[C@@H](O)CP(=O)(CC1CCCCC1)Oc1ccccc1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20130203986A1,CC(C)N.CNc1nc(Cl)nc(Cl)c1[N+](=O)[O-]>>CNc1nc(Cl)nc(NC(C)C)c1[N+](=O)[O-],,ClCCl,,CCN(C(C)C)C(C)C,,test
US20130274260A1,COC(=O)c1cccc(Cc2cccc(F)c2)c1>>O=C(O)c1cccc(Cc2cccc(F)c2)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20050107423A1,O=C(OCc1ccccc1)N1CC2CC(F)(F)C(O)C2C1>>OC1C2CNCC2CC1(F)F,[Pd],CCO,CO,[H][H],,test
US20080009530A1,CCOC(=O)/C(=C/c1ccc(OCCOC)cc1Oc1ncc(Cl)cc1Cl)CC>>CC/C(=C\c1ccc(OCCOC)cc1Oc1ncc(Cl)cc1Cl)C(=O)O,,C1CCOC1,CCO,[Na+].[OH-],,test
US20100056515A1,CCC(CC)c1ccc(Cl)c2c1nc(Cl)n2Cc1ccc(OC)cc1.Cc1cc(Cl)cc(Cl)c1O>>CCC(CC)c1ccc(Cl)c2c1nc(Oc1c(C)cc(Cl)cc1Cl)n2Cc1ccc(OC)cc1,,O,,CN1CCCC1=O,O=C([O-])[O-].[K+].[K+],test
US20040242659A1,CSCCc1nccn1CCCCc1ccc(O)cc1.Fc1ccc(/C=C/c2nc(CCl)co2)cc1>>CSCCc1nccn1CCCCc1ccc(OCc2coc(/C=C/c3ccc(F)cc3)n2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20130261125A1,O=NN1CCCC(CO)(Oc2cc(F)ccc2F)C1>>NN1CCCC(CO)(Oc2cc(F)ccc2F)C1,[Zn],CC(=O)O,O,,,test
US20120309966A1,CC(=O)N1CCN([C@@H]2CC[C@@H](c3ncc4c(C)nccn34)CC2)CC1.O=C1CCC(=O)N1Br>>CC(=O)N1CCN([C@@H]2CC[C@@H](c3nc(Br)c4c(C)nccn34)CC2)CC1,,CN(C)C=O,,,,test
US05858275,CCC[C@H]1CC[C@H](CC[C@@H]2CC[C@@H](c3ccccc3)CC2)CC1.O=C(Cl)C(=O)Cl>>CCC[C@H]1CC[C@H](CC[C@@H]2CC[C@@H](c3ccccc3C(=O)Cl)CC2)CC1,,ClCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20110183938A1,N#Cc1ncc2c(c1OC1CCN(CC(F)F)CC1)c1cccnc1n2S(=O)(=O)c1ccccc1>>N#Cc1ncc2[nH]c3ncccc3c2c1OC1CCN(CC(F)F)CC1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20150065522A1,CCOC(=O)C1CCCC1=O.Nc1[nH]ncc1-c1cnn(-c2ccccn2)c1>>O=c1c2c([nH]c3c(-c4cnn(-c5ccccn5)c4)cnn13)CCC2,,CC(=O)O,,,,test
US20150057265A1,CC(C)(C)OC(=O)N1CCCN(c2ccncc2[N+](=O)[O-])CC1>>CC(C)(C)OC(=O)N1CCCN(c2ccncc2N)CC1,[Fe],O,,CCO,[Cl-].[NH4+],test
US20100009970A1,CSc1ccc(O)cc1C.N#Cc1cc(S(=O)(=O)Nc2ccccc2)ccc1F>>CSc1ccc(Oc2ccc(S(=O)(=O)Nc3ccccc3)cc2C#N)cc1C,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20020072533A1,CC(CO)C[C@H]1CC(=O)N([C@@H](C)c2ccccc2)C1.CCN(CC)S(F)(F)F>>CC(CF)C[C@H]1CC(=O)N([C@@H](C)c2ccccc2)C1,,ClCCl,,,,test
US20120184565A1,C=CCCN1C(=O)c2ccccc2C1=O.C[N+]1([O-])CCOCC1.O=[Os](=O)(=O)=O>>O=C1c2ccccc2C(=O)N1CCC(O)CO,O=[Os](=O)(=O)=O,C1CCOC1,,O,,test
US20160207928A1,CN(C)C=O.O=C(O)c1ccc(Br)c(OCC(F)(F)F)c1>>NC(=O)c1ccc(Br)c(OCC(F)(F)F)c1,,C1CCOC1,,O=C(Cl)C(=O)Cl,,test
US04697033,CCC(C)Sc1ccc(O)cc1.O=C1OCCO1>>CCC(C)Sc1ccc(OCCO)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04329556,O=C1C=CC(=O)O1.[N-]=[N+]=NS(=O)(=O)c1ccc(N)cc1>>[N-]=[N+]=NS(=O)(=O)c1ccc(NC(=O)/C=C\C(=O)O)cc1,,ClCCl,,,,test
US20130317231A1,COc1ccc(/C=C\c2cc(OC)c(OC)c(OC)c2)cc1OCC(=O)O.Nc1nc2ccc(C(F)(F)F)cc2s1>>COc1ccc(/C=C\c2cc(OC)c(OC)c(OC)c2)cc1OCC(=O)Nc1nc2ccc(C(F)(F)F)cc2s1,,ClCCl,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20090239845A1,CN1CCNCC1.Cc1cc(NC(=O)c2cnc(Cl)c(Cl)c2)nn1Cc1cc(Cl)ccc1OCC(C)C>>Cc1cc(NC(=O)c2cnc(N3CCN(C)CC3)c(Cl)c2)nn1Cc1cc(Cl)ccc1OCC(C)C.Cl,,CN1CCCC1=O,,,,test
US05206399,CC(C)=CCC/C(C)=C/CO>>CC(C)=CCCC(C)CCO,,CO,,[H][H],,test
US20080300412A1,C1CNC1.O=C(O)c1ccc(O)cc1>>O=C(c1ccc(O)cc1)N1CCC1,,CC#N,,,,test
US20080318950A1,CCN(CC)CCCl.NCc1ccccc1>>CCN(CC)CCNCc1ccccc1,,CC(C)(C)O,,CCN(CC)CC,Cl,test
US20030220348A1,COc1cnc(CO)c(Cl)n1.O=S(Cl)Cl>>COc1cnc(CCl)c(Cl)n1,,ClCCl,,,,test
US05240935,CCOC(=O)C1CC2C(CC)=CC1N(C)C2Cc1ccccc1.Cl>>CCOC(=O)C1CC2C(CC)CC1N(C)C2Cc1ccccc1.Cl,[Pd],CCO,,,,test
US20080171743A1,C[C@H]1COCCN1.O=S(=O)(Cc1cc(Cl)nc(Cl)n1)c1ccc(F)cc1>>C[C@H]1COCCN1c1cc(CS(=O)(=O)c2ccc(F)cc2)nc(Cl)n1,,ClCCl,,CCN(CC)CC,,test
US20040157866A1,CC(=O)[O-].COC(=O)c1ccc(CBr)cc1-c1ccc(C(F)(F)F)cc1>>COC(=O)c1ccc(COC(C)=O)cc1-c1ccc(C(F)(F)F)cc1,,CN(C)C=O,,O,,test
US04939138,Cc1c(Sc2ccccc2)c2cccc3c2n1C(CN1CCOCC1)CO3>>Cc1cc2cccc3c2n1C(CN1CCOCC1)CO3,[Ni],CCO,,,,test
US20090214675A1,CC(N)=CC(=O)OC1CCC1.CC([O-])=CC#N.Cc1cc(=O)c2c(F)ccc(C=O)c2o1>>CC1=C(C#N)C(c2ccc(F)c3c(=O)cc(C)oc23)C(C(=O)OC2CCC2)=C(C)N1,,CC(C)O,,CC(=O)O,,test
US06211242B1,CCOC(=O)CBr.Cc1ccc(-c2ccccc2C(=O)Nc2ccc(C(=O)N(C)c3ccccc3OCC=NO)cc2)cc1>>CCOC(=O)CON=CCOc1ccccc1N(C)C(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C)cc2)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100305145A1,CCOC(=O)[C@H](C)C[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)CCC(=O)NCCC#N.C[Si](C)(C)N=[N+]=[N-]>>CCOC(=O)[C@H](C)C[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)CCc1nnnn1CCC#N,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120070779A1,C=CC(N)=O.C=CP(=O)(O)O>>C=CC(N)=O.C=CP(=O)(O)O,,CCO,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20070299112A1,CCOC(=O)c1cc2sccc2[nH]1.N>>NC(=O)c1cc2sccc2[nH]1,,CO,,[Li+].[OH-],,test
US06340679B1,CC(C)(C)OC(=O)[C@H](Cc1ccc(OCCCC(=O)NC2=NCCCN2)cc1)NS(=O)(=O)c1ccc(Cl)cc1>>O=C(CCCOc1ccc(C[C@H](NS(=O)(=O)c2ccc(Cl)cc2)C(=O)O)cc1)NC1=NCCCN1,,O,O=C(O)C(F)(F)F,,,test
US20100015178A1,NCCCNc1nonc1-c1noc(=O)n1-c1ccc(F)c(Br)c1.NS(N)(=O)=O>>NS(=O)(=O)NCCCNc1nonc1-c1noc(=O)n1-c1ccc(F)c(Br)c1,,c1ccncc1,,I,,test
US20100113440A1,C=CCCCCN(C)C(=O)C1CC(O)CC1C(=O)NC1(C(=O)NS(=O)(=O)C2CC2)CC1C=C.Clc1ccnc(Cl)n1>>C=CCCCCN(C)C(=O)C1CC(Oc2ccnc(Cl)n2)CC1C(=O)NC1(C(=O)NS(=O)(=O)C2CC2)CC1C=C,,CN(C)C=O,,[H-].[Na+],,test
US20070112038A1,COC(=O)c1ccc(=O)n(C)c1Cl.Nc1ccc(Br)cc1F>>COC(=O)c1ccc(=O)n(C)c1Nc1ccc(Br)cc1F,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20100292222A1,CCN1CCNCC1=O.CS(=O)(=O)OCCCOc1ccc(C2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1>>CCN1CCN(CCCOc2ccc(C3CCN(c4ccc5nnc(C(F)(F)F)n5n4)CC3)cc2)CC1=O,,CN(C)C=O,ClCCl,CCOCC,,test
US06472386B1,COC(=O)[C@H](CO[Si](C)(C)C(C)(C)C)NC(=O)c1cc(OC)c(OC)c(OC)c1>>COC(=O)[C@H](CO)NC(=O)c1cc(OC)c(OC)c(OC)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080312286A1,CC1(C2CCCC2)Cc2cc(OCCCCC#N)c(Cl)c(Cl)c2C1=O.C[Si](C)(C)N=[N+]=[N-]>>CC1(C2CCCC2)Cc2cc(OCCCCc3nn[nH]n3)c(Cl)c(Cl)c2C1=O,,Cc1ccccc1,,CCCC[Sn](=O)CCCC,,test
US20010051633A1,CCCC(Br)C(=O)OC.c1ccc(CC2CCNCC2)cc1>>COC(=O)CCCCN1CCC(Cc2ccccc2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130023530A1,CC(=O)c1ccc(Cl)c(Cl)c1.CCOC(=O)C(=O)OCC>>CCOC(=O)C(=O)CC(=O)c1ccc(Cl)c(Cl)c1,,c1ccccc1,,Cl,CC(C)(C)[O-].[K+],test
US20150038528A1,COC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O.N[C@@H](CO)CC(=O)O>>N#Cc1nc(C(=O)N[C@@H](CO)CC(=O)O)c(O)c2ccc(Oc3ccccc3)cc12,,COCCO,,C[O-].[Na+],,test
US07407949B2,CN1CCCNCC1.Cc1cc(C(=O)N2Cc3cnn(C)c3Nc3ccccc32)ccc1CN.O=C(n1ccnc1)n1ccnc1>>Cc1cc(C(=O)N2Cc3cnn(C)c3Nc3ccccc32)ccc1CNC(=O)N1CCCN(C)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20120208842A1,CC(C)(C)OC(=O)NCCCN1C(=O)c2cc([N+](=O)[O-])ccc2CC1c1ccc(C#N)cc1>>CC(C)(C)OC(=O)NCCCN1C(=O)c2cc(N)ccc2CC1c1ccc(C#N)cc1,[Pd],CO,,[H][H],,test
US20160218303A1,Cc1ccccc1N.N#Cc1cccc(F)c1[N+](=O)[O-]>>Cc1ccccc1NC1([N+](=O)[O-])C=CC=CC1C#N,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US08080566B1,CCn1c2ccccc2c2cc(CN3CCCC(C(=N)OC)C3)ccc21.NNC=O>>CCn1c2ccccc2c2cc(CN3CCCC(c4ncn[nH]4)C3)ccc21,,O,c1ccncc1,Cl,,test
US20090286790A1,CCC1CC(N(Cc2cc(Cl)cc(C(F)(F)F)c2)C(=O)OC)CC(CC(=O)C#C[Si](C)(C)C)N1C(=O)OC(C)C.NN>>CCC1CC(N(Cc2cc(Cl)cc(C(F)(F)F)c2)C(=O)OC)CC(Cc2cc[nH]n2)N1C(=O)OC(C)C,,CCO,,O,,test
US04336332,C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>C[C@]12CCC(=O)C=C1C[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12,,CS(C)=O,,,,test
US20030158197A1,Cc1cc(C)c(-n2c(C)nc3c(NC(=O)CCl)cc(C)nc32)c(C)c1>>Cc1cc(C)c(-n2c(C)nc3c(NCCCl)cc(C)nc32)c(C)c1,,C1CCOC1,,,,test
US20140128424A1,CN(C)C=O.Cc1nc2c(OCc3c(F)cccc3F)cccn2c1C(=O)O.ClCCl>>COC(=O)CCNC(=O)c1c(C)nc2c(OCc3c(F)cccc3F)cccn12,,ClCCl,,,,test
US20130225808A1,COC(=O)C1(c2ccc(C(F)(F)F)c([N+](=O)[O-])c2)CC1>>COC(=O)C1(c2ccc(C(F)(F)F)c(N)c2)CC1,[Fe],CC(=O)O,CCOC(C)=O,,,test
US04143159,CCOC(=O)C(C)O.NCCO>>CC(O)C(=O)NCCO,,CCO,,,,test
US20060160838A1,O=C1OCCC1Br.OCc1ccc(S)cc1>>O=C1OCCC1Sc1ccc(CO)cc1,,ClCCl,,CCN(CC)CC,,test
US20070117839A1,COc1cc(/C=C2\CC[C@@H]3C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@@H](c4cc(F)c(F)c(F)c4)N3C2=O)ccc1-n1cnc(C)c1>>COc1cc(/C=C2\CC[C@@H]3C[C@@H](O)C[C@@H](c4cc(F)c(F)c(F)c4)N3C2=O)ccc1-n1cnc(C)c1,,C1CCOC1,,CCOC(C)=O,[Cl-].[NH4+],test
US20020016465A1,CC(C(O)c1ccc(O)cc1)N1CCC(O)(c2ccccc2)CC1.O=C(O)[C@@H](O)[C@H](O)C(=O)O>>C[C@@H]([C@@H](O)c1ccc(O)cc1)N1CCC(O)(c2ccccc2)CC1.O=C([O-])[C@@H](O)[C@H](O)C(=O)[O-],,CO,,,,test
US20090275590A1,CC(C)(C)OC(=O)N1CCc2[nH]c3cc(Br)ccc3c2C1.CI>>Cn1c2c(c3ccc(Br)cc31)CN(C(=O)OC(C)(C)C)CC2,,CN(C)C=O,,[H-].[Na+],,test
US05369110,CCCCN(Cc1ccc(-c2ccccc2C#N)cc1)C(=O)[C@@H](N)C(C)C.CS(=O)(=O)Cl>>CCCCN(Cc1ccc(-c2ccccc2C#N)cc1)C(=O)[C@@H](NS(C)(=O)=O)C(C)C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100158818A1,CC(C)(CC(=O)Cl)N=[N+]=[N-].CCNC>>CCN(C)C(=O)CC(C)(C)N=[N+]=[N-],,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100130556A1,COC(=O)c1ccc(C(=O)c2ccccc2)o1>>O=C(O)c1ccc(C(=O)c2ccccc2)o1,,CO,,[Na+].[OH-],,test
US20140357858A1,Nc1ccc(N2C(=O)CC(=O)Nc3c2ccc2ccccc32)cc1.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=C1CC(=O)N(c2ccc(NS(=O)(=O)c3ccccc3[N+](=O)[O-])cc2)c2ccc3ccccc3c2N1,,c1ccncc1,,,,test
US20050203081A1,COC(=O)c1sc2ncc(Br)cc2c1OCC(=O)OC(C)(C)C>>O=C(O)COc1c(C(=O)O)sc2ncc(Br)cc12,,C1CCOC1,O,[Li+].[OH-],,test
US20090023729A1,CCCNCC1CC1.O=Cc1cc(Cl)cnc1F>>CCCN(CC1CC1)c1ncc(Cl)cc1C=O,,Cc1ccccc1,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20070148566A1,C1=CC2CCC1C2.C1CCOC1.COCC1CO1.Cc1ccccc1>>C1=CC2CCC1C2.CCCCC12C=CC(CC1)C2.COCC1CO1,,Cc1ccccc1,,,,test
US04471117,O=[N+]([O-])c1ccc2c(c1)SC1=NCCCN12>>Nc1ccc2c(c1)SC1=NCCCN12,[Pt],CO,,N,[H][H],test
US20110195954A1,COc1ccc2c(c1)CCN(C1CCN(c3cc(C(=O)O)ncn3)CC1)C(=O)N2.Cc1cc(N)cc2cn[nH]c12>>COc1ccc2c(c1)CCN(C1CCN(c3cc(C(=O)Nc4cc(C)c5[nH]ncc5c4)ncn3)CC1)C(=O)N2,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,test
US05597922,Nc1cc(Cl)c(Cl)cc1N.O=C(O)C(=O)c1ccccc1>>O=c1[nH]c2cc(Cl)c(Cl)cc2nc1-c1ccccc1,,CCO,,,,test
US20040014751A1,O=c1cc(Nc2ccccc2)n(-c2ccccc2)c2nc(CO)c(F)cc12>>O=Cc1nc2c(cc1F)c(=O)cc(Nc1ccccc1)n2-c1ccccc1,O=[Mn]=O,ClC(Cl)Cl,,,,test
US20100087427A1,CCOC(=O)/C=C/CCc1ccccc1.COCN(Cc1ccccc1)[Si](C)(C)C.Cc1ccccc1>>CCOC(=O)[C@H]1CN(Cc2ccccc2)C[C@@H]1CCc1ccccc1,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US07160887B1,CC(C)(C)OC(=O)NCc1cccc(Oc2cc(Cl)ccc2N(Cc2ccc(O)cc2)C(=O)CCC(=O)O)c1.NCc1ccccc1F>>CC(C)(C)OC(=O)NCc1cccc(Oc2cc(Cl)ccc2N(Cc2ccc(O)cc2)C(=O)CCC(=O)NCc2ccccc2F)c1,,CN(C)C=O,O,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20150080412A1,NN.O=C(O)CC1CC1c1ccc(Br)cc1>>NNC(=O)CC1CC1c1ccc(Br)cc1,,C1CCOC1,,O,O=C(n1ccnc1)n1ccnc1,test
US20070167443A1,COC=C(C(=O)OC)C(=O)c1ccc(C)c(C)c1.Cc1ccc(N)c(C)n1>>Cc1cc2c(=O)c(C(=O)c3ccc(C)c(C)c3)c[nH]c2c(C)n1,,CCCCCC,,c1ccc(Oc2ccccc2)cc1,,test
US20040204463A1,CC(=O)NC[C@H]1CN(c2ccc(N3CCN(C(=O)CCCC#Cc4cccc(C#N)c4)CC3)c(F)c2)C(=O)O1.Cl.NO>>CC(=O)NC[C@H]1CN(c2ccc(N3CCN(C(=O)CCCC#Cc4ccc(/C(N)=N/O)cc4)CC3)c(F)c2)C(=O)O1.Cl,,CCO,O,CCN(CC)CC,,test
US20060009472A1,CC(C)(C)[C@@H](N)c1nc(-c2cc(F)ccc2F)cn1Cc1ccccc1.COC[C@H](CC=O)NC(=O)OC(C)(C)C>>COC[C@H](CCN[C@@H](c1nc(-c2cc(F)ccc2F)cn1Cc1ccccc1)C(C)(C)C)NC(=O)OC(C)(C)C,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05276007,FC(F)(F)Oc1cc(Cl)nc(Cl)n1.N>>NC1(Cl)C=CN=C(Cl)N1,,COC(C)(C)C,,,,test
US20100222347A1,CC(=O)OC1CC(C)N(C(C)=O)c2cc(F)ccc21>>CC(=O)N1c2cc(F)ccc2[C@@H](O)C[C@@H]1C,,CCO,,O,[Na+].[OH-],test
US20070185107A1,CN1CCN(c2cc(F)cc3c2OC(C(=O)O)CC3)CC1.CN1CCN(c2ccc(N)cc2)CC1>>CN1CCN(c2ccc(NC(=O)C3CCc4cc(F)cc(N5CCN(C)CC5)c4O3)cc2)CC1,,CO,,Cl,,test
US20090176778A1,CC(=O)OC(C)=O.NC1CCN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)C1>>CC(=O)NC1CCN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)C1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,Cl,test
US20160016908A1,C1CCNC1.CC(=O)N1c2ccc(C(=O)O)cc2[C@H](Nc2cccc(C)n2)[C@@H](C)[C@@H]1C1CC1>>CC(=O)N1c2ccc(C(=O)N3CCCC3)cc2[C@H](Nc2cccc(C)n2)[C@@H](C)[C@@H]1C1CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05874466,CON=Cc1cc(C(=O)O)cc(Cl)c1N.O=S(Cl)Cl>>CON=Cc1cc(C(=O)Cl)cc(Cl)c1N,,CN(C)C=O,,Cc1ccccc1,,test
US20050113400A1,COCCl.Cc1cc(CO)ccc1Br>>COCOCc1ccc(Br)c(C)c1,,ClCCl,O,CCN(C(C)C)C(C)C,Cl,test
US05280015,Nc1cccc(C(=O)O)c1.O=C(Cl)OCc1ccccc1>>O=C(Nc1cccc(C(=O)O)c1)OCc1ccccc1,,CO,,O,,test
US20140243310A1,COCOc1cnc(CO[Si](C)(C)C(C)(C)C)cc1F>>COCOc1cnc(CO)cc1F,,C1CCOC1,,[Cl-].[NH4+],,test
US05866568,COc1nc(C)cnc1NS(=O)(=O)c1cccnc1-c1ccc(COC(C)COC(C)(C)C)cc1>>COc1nc(C)cnc1NS(=O)(=O)c1cccnc1,,O=C(O)C(F)(F)F,,[Cl-].[NH4+],,test
US20100022486A1,BrCc1ccccc1-c1ccccc1.Cc1cc(N2C(=O)c3ccccc3C2=O)n[nH]1>>Cc1cc(N2C(=O)c3ccccc3C2=O)nn1Cc1ccccc1-c1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04935509,CC(=O)Cl.OC[C@@H]1CCCC[C@@H]1CC1SCCS1>>CC(=O)OC[C@@H]1CCCC[C@@H]1CC1SCCS1,,ClCCl,,c1ccncc1,,test
US20100331317A1,CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(O)ccc21.O=c1c2ccccc2ccn1CCN(CCCI)S(=O)(=O)c1ccccc1[N+](=O)[O-]>>CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCn3ccc4ccccc4c3=O)S(=O)(=O)c3ccccc3[N+](=O)[O-])ccc21,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130260402A1,CC(=O)O[C@H]1C(O[C@@H]2[C@@H](COCc3ccccc3)O[C@H](OCCCCCN(Cc3ccccc3)C(=O)OCc3ccccc3)[C@H](N=[N+]=[N-])[C@H]2OCc2ccc3ccccc3c2)O[C@H](COCc2ccccc2)[C@H](OCc2ccccc2)[C@@H]1OCc1ccccc1>>CC(=O)O[C@H]1[C@H](O[C@@H]2[C@@H](COCc3ccccc3)O[C@H](OCCCCCN(Cc3ccccc3)C(=O)OCc3ccccc3)[C@H](N=[N+]=[N-])[C@H]2O)O[C@H](COCc2ccccc2)[C@H](OCc2ccccc2)[C@@H]1OCc1ccccc1,,ClCCl,O,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20090239911A1,CS(=O)(=O)Cl.O=C1[C@H](Cc2c(Cl)cc(OCc3ccccc3)cc2Cl)CCN1[C@@H]1CC[C@@H](O)CC1>>CS(=O)(=O)O[C@@H]1CC[C@@H](N2CC[C@@H](Cc3c(Cl)cc(OCc4ccccc4)cc3Cl)C2=O)CC1,,ClCCl,,CCN(CC)CC,,test
US20060241126A1,N#Cc1cc(CCC(=O)O)ccc1F.O=C(Cl)C(=O)Cl>>N#Cc1cc(CCC(=O)Cl)ccc1F,,ClCCl,,CN(C)C=O,,test
US05110956,BrBr.CC(C)c1ccc2c(c1)OCO2>>CC(C)c1cc2c(cc1Br)OCO2,,ClC(Cl)(Cl)Cl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20090270435A1,COc1ccc2c(c1)OC1(CCN(C(=O)OC(C)(C)C)CC1)CC2=O.Cl>>COc1ccc2c(c1)OC1(CCNCC1)CC2=O.Cl,,C1COCCO1,CO,,,test
US20020161006A1,COC(=O)CC1=C(C(=O)OC)C(c2c(Cl)cccc2Cl)C(C(=O)OC)=C(CCc2ccccc2N)N1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)CC1=C(C(=O)OC)C(c2c(Cl)cccc2Cl)C(C(=O)OC)=C(CCc2ccccc2NS(=O)(=O)C(F)(F)F)N1,,ClCCl,,CCN(CC)CC,,test
US20100273764A1,COc1ccc(Nc2nc(N3CCOCC3)ncc2-c2nc(C)nc(SC)n2)cn1.N>>COc1ccc(Nc2nc(N3CCOCC3)ncc2-c2nc(C)nc(N)n2)cn1,,C1COCCO1,,,,test
US04272533,Cc1c(CCN(C)C)n(-c2ccc(Cl)cc2)c2ccc(Cl)cc12>>CC1c2cc(Cl)ccc2N(c2ccc(Cl)cc2)C1CCN(C)C,,CC(C)=O,,Cl,,test
US20140275179A1,CCOC(=O)CCc1ccc(OC)c(C(F)(F)F)c1F>>CCOC(=O)CCc1ccc(O)c(C(F)(F)F)c1F,,ClCCl,,BrB(Br)Br,,test
US04202894,CCC(C)(C)c1ccc(CC(C)CN2CCCCC2)cc1>>CCC(C)(C)C1CCC(CC(C)CN2CCCCC2)CC1,O=[Pt]=O,CC(=O)O,,[O-][Cl+3]([O-])([O-])O,,test
US20100120860A1,CC(C)(C)OC(=O)N1CCC(Nc2nnc(C#N)s2)CC1>>N#Cc1nnc(NC2CCNCC2)s1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130116243A1,CN(C)C=C1C(=O)c2cc(-c3ccccc3)c(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)nc2CC1(C)C.NN>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)-c3n[nH]cc3C(C)(C)C4)cc2)CCC1,,CCO,,O,,test
US20150361098A1,CC(O)CC(=O)NN.COc1cccc2c(Cl)nc(Cl)nc12>>COc1cccc2c(NNC(=O)CC(C)O)nc(Cl)nc12,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20060004018A1,CCO.CC[C@]1(C(=O)O)C=C[C@@H](NC(=O)OC(C)(C)C)C1>>CC[C@]1(C(=O)OC)C=C[C@@H](NC(=O)OC(C)(C)C)C1,[Pd],,,,,test
US20080058369A1,CC(C)(C)OC(=O)c1ccc(C#CCCO)cc1>>CC(C)(C)OC(=O)c1ccc(CCCCO)cc1,O=[Pt]=O,CCO,CCOC(C)=O,,,test
US20050107619A1,CC(C)C#CC(=O)O.COc1ccc(CCN)cc1OC>>COc1ccc(CCNC(=O)C#CC(C)C)cc1OC,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20080039437A1,CCOC(=O)CC(=O)CF.COC(OC)N(C)C.N#CCC(N)=O>>CCOC(=O)c1cc(C#N)c(=O)[nH]c1CF,,CC(=O)O,CCO,C,C[O-].[Na+],test
US20070167449A1,O=CCc1cccc(Br)c1.Oc1ccc(Nc2ncc(-c3ccsc3)s2)cc1>>Oc1ccc(Nc2ncc(-c3cccc(Br)c3)s2)cc1,,CO,ClCCl,,,test
US20090215778A1,COc1ccc(-c2nc3c(C(=O)O)cnn3c(C(F)(F)F)c2C)cc1.C[C@@H]1CN([C@@H](CO)c2ccccc2)CCN1>>COc1ccc(-c2nc3c(C(=O)N4CCN([C@@H](CO)c5ccccc5)C[C@H]4C)cnn3c(C(F)(F)F)c2C)cc1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05892045,COc1ccc(Cl)cc1-c1c(O)c(=O)[nH]c2cc(Cl)cc(Cl)c12>>O=c1[nH]c2cc(Cl)cc(Cl)c2c(-c2cc(Cl)ccc2O)c1O,,ClCCl,,BrB(Br)Br,O,test
US20150119405A1,C=CC(=O)N[C@H]1CN(C(=O)OC(C)(C)C)C[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)ccc2n1>>C=CC(=O)N[C@H]1CNC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)ccc2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04064266,BrBr.CC(C)(C)c1cc(C=O)ccc1O>>CC(C)(C)c1cc(C=O)cc(Br)c1O,,CC(=O)O,,,,test
US20080269335A1,CCOC(=O)CBr.Oc1ccc(Cl)cc1C1CCCCCC1>>CCOC(=O)COc1ccc(Cl)cc1C1CCCCCC1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20160083403A1,Cc1cc(C)cc(C(=O)N(NC(=O)c2ccc(B3OC(C)(C)C(C)(C)O3)c(NCC#N)c2)C(C)(C)C)c1>>Cc1cc(C)cc(C(=O)N(NC(=O)c2ccc(B(O)O)c(NCC#N)c2)C(C)(C)C)c1,,C1CCOC1,,Cl,O,test
US20160046564A1,Cc1cc([N+](=O)[O-])c(C)cc1OCC1CC1C>>Cc1cc(OCC2CC2C)c(C)cc1N,[Fe],O,,CC(=O)O,,test
US20040209892A1,Nc1cc(Oc2ccnc(C(=O)NCCCCN3CCCC3)c2)ccc1O.S=C=Nc1ccc(Cl)cc1>>O=C(NCCCCN1CCCC1)c1cc(Oc2ccc3oc(Nc4ccc(Cl)cc4)nc3c2)ccn1,,CC#N,CN(C)C=O,ClCCCl,,test
US20110237584A1,C[Si](C)(C)C(F)(F)F.O=Cc1cnc(N2CCOCC2)s1>>OC(c1cnc(N2CCOCC2)s1)C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130303507A1,CO[C@@H]1CC[C@H](NC(=O)OCc2ccccc2)C[C@H]1NC(=O)OC(C)(C)C>>CO[C@@H]1CC[C@H](N)C[C@H]1NC(=O)OC(C)(C)C,[Pd],CO,,,,test
US20110207711A1,COc1cc(-c2cnn(C)c2)cn2ncc(CN3CC4(CCN(C(=O)OC(C)(C)C)CC4)C3)c12>>COc1cc(-c2cnn(C)c2)cn2ncc(CN3CC4(CCNCC4)C3)c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US04866077,CI.N#Cc1cccnc1>>C[n+]1cccc(C#N)c1.[I-],,CC(C)=O,,,,test
US20120157432A1,c1ccc(CN2CC3CCC(C2)C3n2cnnn2)cc1>>c1nnnn1C1C2CCC1CNC2,[Pd],CO,,[H][H],,test
US20100009957A1,COc1ccc(CN2CCOC[C@@H](N)C2)cc1.O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O>>COc1ccc(CN2CCOC[C@@H](NC(=O)ON3C(=O)CCC3=O)C2)cc1,,CC#N,,,,test
US20090221603A1,CC1CN(CC2CCN(C)CC2)CC(C)N1.O=C(O)CS(=O)C(c1ccccc1)c1ccccc1>>CC1CN(CC2CCN(C)CC2)CC(C)N1C(=O)CS(=O)C(c1ccccc1)c1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US05359068,Cc1cc(Cl)ccc1Cl.O=[N+]([O-])O>>Cc1cc(Cl)c([N+](=O)[O-])cc1Cl,,CC(=O)O,,O=S(=O)(O)O,,test
US20070142638A1,O=C(NCCC[C@H]1C(=O)OCN1C(=O)OCC1c2ccccc2-c2ccccc21)OCc1ccccc1>>CN(C(=O)OCC1c2ccccc2-c2ccccc21)[C@@H](CCCNC(=O)OCc1ccccc1)C(=O)O,,ClC(Cl)Cl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20060211709A1,CNC(=O)c1nc(-c2cccc(N)c2)cnc1N.COc1ccc(C(=O)Cl)cc1>>CNC(=O)c1nc(-c2cccc(NC(=O)c3ccc(OC)cc3)c2)cnc1N,,C1CCOC1,,CCN(CC)CC,,test
US20140179662A1,C1COCCN1.NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1>>NS(=O)(=O)Cc1cccc(Nc2ncnc(N3CCOCC3)n2)c1,,C1CCOC1,CC(C)O,CCN(C(C)C)C(C)C,,test
US20090286782A1,CSc1ncc(C(O)c2cn([Si](C(C)C)(C(C)C)C(C)C)c3ncncc23)cn1>>CSc1ncc(Cc2c[nH]c3ncncc23)cn1,,ClCCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US06150373,Cc1cccc(Cl)c1N1Cc2cnc(Nc3ccccc3)nc2N(c2cccc(CCN3C(=O)c4ccccc4C3=O)c2)C1=O>>Cc1cccc(Cl)c1N1Cc2cnc(Nc3ccccc3)nc2N(c2cccc(CCN)c2)C1=O,,CCO,,NN,O,test
US20150315198A1,Cc1nc2ccc(Cl)cn2n1.O=C1CCC(=O)N1Br>>Clc1ccc2nc(CBr)nn2c1,,ClC(Cl)(Cl)Cl,,,,test
US20100298293A1,CCI.COc1cc([N+](=O)[O-])ccc1-c1ccc[nH]c1=O>>CCn1cccc(-c2ccc([N+](=O)[O-])cc2OC)c1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100160369A1,CC(C)(C)OC(=O)CCc1ccc(C#N)c(Cl)c1.NO>>CC(C)(C)OC(=O)CCc1ccc(C(=N)N)c(Cl)c1,,CCO,,CCN(CC)CC,Cl,test
US20110028390A1,CCOC(=O)CCC(=O)OCC.Cc1n[nH]cc1C=O>>CCOC(=O)C(=Cc1c[nH]nc1C)CC(=O)O,,CC(C)(C)O,,CC(C)(C)[O-].[K+],,test
US20160108056A1,COC(=O)CS.O=Cc1cc([N+](=O)[O-])c(Cl)cc1F>>COC(=O)c1cc2cc([N+](=O)[O-])c(Cl)cc2s1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04847289,N.O=S(=O)(Cl)c1cc(S(=O)(=O)c2ccc(CBr)cc2)cs1>>NS(=O)(=O)c1cc(S(=O)(=O)c2ccc(CBr)cc2)cs1,,ClC(Cl)Cl,,,,test
US05166347,CC(C)OC(=NC#N)c1cccnc1.NC(Cc1ccccc1)c1ccccc1>>N#CNC(=NC(Cc1ccccc1)c1ccccc1)c1cccnc1,,CO,,,,test
US03952031,CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@@H]5O[C@@H]5C[C@]4(C)[C@H]3C(=O)C[C@]12C.[Li]C>>CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@@H](C)C[C@]4(C)[C@H]3C(=O)C[C@]12C,,CCOCC,,[Cl-].[NH4+],,test
US20090124616A1,CCOC(=O)c1[nH]c2ccccc2c1CCCO.CS(=O)(=O)Cl>>CCOC(=O)c1[nH]c2ccccc2c1CCCOS(C)(=O)=O,,CC#N,,CCN(CC)CC,,test
US20070082890A1,CCOC(=O)Cn1cccc(OC)c1=O.NN>>COc1cccn(CC(=O)NN)c1=O,,CCO,,O,,test
US20060211698A1,COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccc4nc(-c5sc(C)nc5C)ccc4c3)[nH]c2c1.ClCCN1CCOCC1>>Cc1nc(C)c(-c2ccc3cc(-c4c(C5CCCCC5)c5ccc(C(=O)O)cc5n4CCN4CCOCC4)ccc3n2)s1,,CN(C)C=O,,Cl,[H-].[Na+],test
US04329353,CCOC(=O)N1CCC2(CC1)C(=O)N(C)CN2c1ccc(F)cc1>>CN1CN(c2ccc(F)cc2)C2(CCNCC2)C1=O,,CCCCO,,[Na+].[OH-],,test
US04994569,O=C=Nc1ccccc1.OC1CN=C(c2ccc(Cl)c(Cl)c2)OC1c1ccccc1>>O=C(Nc1ccccc1)OC1CN=C(c2ccc(Cl)c(Cl)c2)OC1c1ccccc1,,ClCCCl,,,,test
US20010027197A1,Clc1ncnc2nc[nH]c12.Nc1cccc(Br)c1>>Brc1cccc(Nc2ncnc3nc[nH]c23)c1,Cl,CC(C)O,,,,test
US20100210706A1,CN1C[C@@H](N(C(=O)[O-])C(C)(C)C)CC1=O.N#Cc1ccc(F)cc1Cl>>CN1C[C@@H](Nc2ccc(C#N)c(Cl)c2)CC1=O,,C1COCCO1,Cl,O=C([O-])O.[Na+],,test
US20090118199A1,Cc1ccc(S(=O)(=O)OCC(F)(F)F)cc1.O=Cc1ccc(O)cc1>>O=Cc1ccc(OCC(F)(F)F)cc1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US04051183,NC1CCCc2ccccc21.O=C=NC(=O)c1ccccc1>>O=C(NC(=O)c1ccccc1)NC1CCCc2ccccc21,,CCOCC,,,,test
US20080319188A1,C1CCOC1.CCN(CC)CC.Nc1cc(Oc2cc(F)c(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ccn1.O.O=C(Cl)Oc1ccccc1>>O=C(Nc1cc(Oc2cc(F)c(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ccn1)N1CC(CO)C1,,C1CCOC1,O,CCOC(C)=O,,test
US20120041012A1,COC(=O)CN1CC2(CCN(C(=O)OC(C)(C)C)CC2)CC1=O.O=C(O)C(F)(F)F>>COC(=O)CN1CC2(CCNCC2)CC1=O.O=C(O)CC(F)(F)F,,ClCCl,,,,test
US20080275038A1,Nc1cc(-c2ccncc2F)c(-c2cccnc2)nc1N.O=C(O)c1ccncc1Cl>>NC1(NC(=O)c2ccncc2Cl)C=CC(c2ccncc2F)=C(c2cccnc2)N1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020013466A1,COc1cccc(Oc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2Br)c1.N#C[Cu]C#N>>COc1cccc(Oc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2C#N)c1,,O,,CN1CCCC1=O,,test
US20080015187A1,CN1CCn2nc(C(=O)N3CCc4ccccc4C3)c(OCc3ccccc3)c2C1=O>>CN1CCn2nc(C(=O)N3CCc4ccccc4C3)c(O)c2C1=O,,Br,CC(=O)O,,,test
US20090221555A1,CC(=O)OCCBr.CN1CCNCc2ccc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4NS(C)(=O)=O)n3)cc21>>CC(=O)OCCN1CCN(C)c2cc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4NS(C)(=O)=O)n3)ccc2C1,,CO,ClCCl,CCN(CC)CC,CN(C)C=O,test
US20080306049A1,ClCCNCCCl.Nc1ccc2[nH]cc3c(=O)n(-c4ccccc4)nc-3c2c1>>O=c1c2c[nH]c3ccc(N4CCNCC4)cc3c-2nn1-c1ccccc1,,Clc1ccccc1,,Cl,,test
US20070276019A1,CC[C@H](N)C(O)c1nc2ccccc2o1.O=C(O)[C@H](Cc1ccccc1Cl)NC(c1ccccc1)C(F)(F)F>>CC[C@H](NC(=O)[C@H](Cc1ccccc1Cl)NC(c1ccccc1)C(F)(F)F)C(O)c1nc2ccccc2o1,,CCOC(C)=O,CN(C)C=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20120178742A1,COC(=O)c1cnn2cc(Br)ccc12>>Brc1ccc2ccnn2c1,,O=S(=O)(O)O,,O=C([O-])O.[Na+],,test
US20080242681A1,CC(C)(C)OC(=O)Nc1ccc(Nc2cc(-c3ccc(F)cc3)ncn2)cc1>>Nc1ccc(Nc2cc(-c3ccc(F)cc3)ncn2)cc1,,C1COCCO1,,Cl,,test
US20140031349A1,CC1=C(N2CC(=O)C3(CCN(C(=O)OC(C)(C)C)CC3)C2=O)COC1=O.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC1=C(N2C=C(OS(=O)(=O)C(F)(F)F)C3(CCN(C(=O)OC(C)(C)C)CC3)C2=O)COC1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20130178505A1,COc1ccccc1OC.Cl.O=C1CCC(=O)O1>>COc1ccc(C(=O)CCC(=O)O)cc1OC.Cl,,O=[N+]([O-])c1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120309750A1,CCCC[Sn](CCCC)(CCCC)c1cnn(C)c1.CCNC(=O)c1noc(-c2cc(C(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)c1I>>CCNC(=O)c1noc(-c2cc(C(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)c1-c1cnn(C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US05627215,C(=C/CN1CCCNC1)\CN1CCCNC1.CCC(=O)OC(=O)CC.c1ccncc1>>CCC(=O)N1CCCN(C/C=C/CN2CCCN(C(=O)CC)C2)C1.N,,c1ccncc1,,,,test
US20020037910A1,CC(C)c1cccc(C(C)C)c1N.O=C(O)CCCCCBr>>CC(C)c1cccc(C(C)C)c1NC(=O)CCCCCBr,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US05589474,O=C1NC2=C(C=CCC2)S(=O)(=O)c2cc(C(F)(F)F)ccc21.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>O=S1(=O)c2ccccc2NC(=S)c2ccc(C(F)(F)F)cc21,,c1ccncc1,,O,,test
US20150087639A1,CCCCCCNCCCCCC.N#Cc1cc([N+](=O)[O-])ccc1F>>CCCCCCN(CCCCCC)c1ccc([N+](=O)[O-])cc1C#N,,CC#N,,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20120214762A1,CC(=O)c1ncc[nH]1.C[Si](C)(C)CCOCCl>>CC(=O)c1nccn1COCC[Si](C)(C)C,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20140018373A1,CCCSc1ccccc1C(=O)O.CNc1ncc(C(F)(F)F)cc1N>>CCCSc1ccccc1-c1nc2cc(C(F)(F)F)cnc2n1C,,O,c1ccncc1,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20070099901A1,CCCc1nc2cnc3cccnc3c2n1CCCC=O.CON>>CCCc1nc2cnc3cccnc3c2n1CCCC=NOC,,CO,,Cl,[Na+].[OH-],test
US20080021217A1,CC(C)(C)OC(=O)NCC(N)=S.O=C(CBr)c1c[nH]c2ncccc12>>CC(C)(C)OC(=O)NCc1nc(-c2c[nH]c3ncccc23)cs1,,CCOC(C)=O,,CCO,,test
US20090182023A1,CC(=O)NCCC1CCc2ccc3nc(S)oc3c21.CI>>CSc1nc2ccc3c(c2o1)C(CCNC(C)=O)CC3,,CCOCC,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20160096827A1,N#Cc1cc(Br)ccc1F.OC1CCC(F)(F)CC1>>N#Cc1cc(Br)ccc1OC1CCC(F)(F)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20090253677A1,CCOC(=O)C=C(C(=O)OCC)N1CC2CC(C1)c1nc(C(=O)OCC)c(O)c(=O)n1C2>>CCOC(=O)c1nc2n(c(=O)c1O)CC1CNCC2C1,,CC#N,,O=C(O)C(F)(F)F,,test
US20090137561A1,C=CC1(c2cc(C(=O)OC)ccc2O)CCCC1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>C=CC1(c2cc(C(=O)OC)ccc2OS(=O)(=O)C(F)(F)F)CCCC1,CN(C)c1ccncc1,c1ccncc1,,CCOC(C)=O,,test
US20110257121A1,COc1ccc(C(Nc2nc(OC)c3ncn([C@@H]4O[C@H](COC(c5ccccc5)(c5ccc(OC)cc5)c5ccc(OC)cc5)[C@@H](OC(=O)OCc5ccccc5)[C@@]4(C)F)c3n2)(c2ccccc2)c2ccc(OC)cc2)cc1>>COc1nc(N)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](OC(=O)OCc2ccccc2)[C@@]1(C)F,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US06265423B1,CC(O)c1cc(Br)cs1>>CC(=O)c1cc(Br)cs1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US04895842,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O.CC1CCC(N)CC1C>>CC1CCC(NC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)NC(=O)OC(C)(C)C)CC1C,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US06093527,Cc1nc2cc(S(=O)(=O)N3CCOCC3)ccc2n1C.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>Cc1n(CC(F)(F)F)c2cc(S(=O)(=O)N3CCOCC3)ccc2[n+]1C.O=S(=O)([O-])C(F)(F)F,,Cc1ccccc1,,,,test
US04703053,COC(=O)c1oc2cc3ccccc3cc2c1O.COS(=O)(=O)OC>>COC(=O)c1oc2cc3ccccc3cc2c1OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06045720,CCBr.CCCCC(O)OCc1ccccc1>>CCCCC(OCC)OCc1ccccc1,,C1CCOC1,,O,[H-].[Na+],test
US20050107364A1,COC1=CCc2ccccc2C1(CO)CCC(C)C>>COC1=CCc2ccccc2C1(C=O)CCC(C)C,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04308277,CCI.S=C1N[C@@H](c2ccccc2)[C@H](c2ccccc2)N1>>CCSC1=N[C@@H](c2ccccc2)[C@H](c2ccccc2)N1.I,,CO,,,,test
US20070244118A1,O=C(Cl)CCl.O=C(OCc1ccccc1)N1CCC(NCCO)CC1>>O=C(OCc1ccccc1)N1CCC(N2CCOCC2=O)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20110311474A1,Cc1ccc(S(=O)(=O)n2ccc3nc(NNC(=O)[C@@H]4CC[C@@H](NC(=O)OC(C)(C)C)C4)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c2ncc2nnc([C@@H]4CC[C@@H](N)C4)n23)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,O=S(Cl)Cl,test
US20130011361A1,CC(C)=O.COc1ccc(Cn2nc(N3CCNC3=O)cc2C(=O)[O-])cc1.Fc1ccc(CBr)cc1>>COC(=O)c1cc(N2CCN(Cc3ccc(F)cc3)C2=O)nn1Cc1ccc(OC)cc1,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050228012A1,COC(=O)[C@H](c1ccccc1Cl)N1CCc2sccc2C1.O=S(=O)(O)c1ccc2ccccc2c1>>COC(=O)[C@H](c1ccccc1Cl)N1CCc2sccc2C1.O=S(=O)([O-])c1ccc2ccccc2c1,,CCOC(C)=O,O,,,test
US20130029987A1,CSc1nc(Cl)ncc1Br.NC12CC(C1)C2>>CSc1nc(NC23CC(C2)C3)ncc1Br,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,Cl,test
US20070287708A1,COCCOc1cc(-c2cn(Cc3ccc(OC)c(OC)c3)cc(C#N)c2=O)ccc1OC.O=P(Cl)(Cl)Cl>>COCCOc1cc(-c2cncc(C#N)c2Cl)ccc1OC,,O=P(Cl)(Cl)Cl,,[Cl-].[Li+],,test
US20060229330A1,COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CN(C(=O)OC(C)(C)C)C2)nc1N>>COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CNC2)nc1N,,ClCCl,O=C(O)C(F)(F)F,,,test
US20050187236A1,N#Cc1cnc(N)cc1Cl.Oc1ccc2[nH]ccc2c1>>N#Cc1cnc(N)cc1Oc1ccc2[nH]ccc2c1,,CS(C)=O,,[H-].[Na+],,test
US03952001,CCCCSc1nc[nH]n1.OO>>CCCCS(=O)c1nc[nH]n1,,CC(=O)O,,,,test
US05047540,CCCCCCCCCCCCCCCCCCNC(=O)OCC(CN=[N+]=[N-])CC(C)OC(=O)c1ccccc1>>CCCCCCCCCCCCCCCCCCNC(=O)OCC(CN)CC(C)OC(=O)c1ccccc1,[Pd],CO,,,,test
US20100172916A1,N#CCc1cccc(OCc2ccccc2)c1>>NCCc1cccc(O)c1,[Ni],CO,,O,[H][H],test
US20120094917A1,CC(C)(C)OC(=O)NC(C(=O)N1CCC2C1C(C(=O)Nc1cccc3ccccc13)CN2C(=O)CNC(=O)OCc1ccccc1)C(C)(C)C>>CC(C)(C)C(N)C(=O)N1CCC2C1C(C(=O)Nc1cccc3ccccc13)CN2C(=O)CNC(=O)OCc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110020278A1,CC(C)(C=O)COC1CCCCO1.COP(=O)(OC)C(=[N+]=[N-])C(C)=O>>C#CC(C)(C)COC1CCCCO1,,CCOCC,CO,O=C([O-])[O-].[K+].[K+],,test
US20080015203A1,COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(C(=O)Nc2ccn(C(=O)OC(C)(C)C)n2)c1>>COC[C@H](C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(C(=O)Nc2cc[nH]n2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100160335A1,Cc1cc(=O)n(C(=O)OC(C)(C)C)nc1-c1ccc(O[Si](C)(C)C(C)(C)C)cc1>>Cc1cc(=O)n(C(=O)OC(C)(C)C)nc1-c1ccc(O)cc1,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US04918074,CCOC(=O)C1=C(C)Nc2c(C(=O)OCC)ncn2C1c1cccc([N+](=O)[O-])c1>>CCOC(=O)C1=C(C)Nc2c(C(=O)O)ncn2C1c1cccc([N+](=O)[O-])c1,,CCO,O,[K+].[OH-],,test
US20100227858A1,Brc1cccc(-c2cn[nH]c2)c1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)n1cc(-c2cccc(Br)c2)cn1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20040097731A1,OC(c1ccc(Nc2ccc(F)cc2F)nc1)c1cc(Br)ccc1Cl>>O=C(c1ccc(Nc2ccc(F)cc2F)nc1)c1cc(Br)ccc1Cl,,CC(C)=O,,O=S(=O)(O)O,O=[Cr](=O)=O,test
US06001341,CCCCCCCCCCC(CO)CCCCCCCC.COCC(C)OCC(COC)OC.O>>CC(O)CO.CC(O)COC(C)CO,,O,,,,test
US05198925,C=C(F)C(=O)Cl.Cc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1C>>C=C(F)C(=O)OC(c1ccc(C)c(C)c1)(C(F)(F)F)C(F)(F)F,,CCOCC,,CCN(CC)CC,,test
US20080132513A1,BrBr.O=C1CCCCC(=O)C1>>O=C1CCCCC(=O)C1Br,,ClCCl,,,,test
US06127414,CC(C)(C)OC(=O)N[C@@H](CCCNC(=O)OCc1ccccc1)C(=O)N[C@@H](CO)c1ccccc1.Cl>>Cl.N[C@@H](CCCNC(=O)OCc1ccccc1)C(=O)N[C@@H](CO)c1ccccc1,,CO,,CCOC(C)=O,,test
US04460584,N#CCCl.NCCCCCc1nccc(NC(N)=NCC(F)(F)F)n1>>N#CCNCCCCCc1nccc(NC(N)=NCC(F)(F)F)n1,,CCO,,CCN(CC)CC,,test
US20070043064A1,CCN(c1cccc(C(=O)C=CN(C)C)c1)S(=O)(=O)c1ccc(OC)cc1.Nc1[nH]ncc1[N+](=O)[O-]>>CCN(c1cccc(-c2ccnc3c([N+](=O)[O-])cnn23)c1)S(=O)(=O)c1ccc(OC)cc1,,CC(=O)O,,CCOC(C)=O,,test
US20030153596A1,Cn1cccc1C#N.O=[N+]([O-])O>>Cn1cc([N+](=O)[O-])cc1C#N,,CC(=O)O,,[Na+].[OH-],,test
US04150153,Br.CC(=O)c1cccc2ccccc12>>O=C(CBr)c1cccc2ccccc12,Br[Cu]Br,CCOC(C)=O,,ClC(Cl)Cl,,test
US20100004217A1,CCO.CNC1(c2ccccc2Cl)CCCCC1=O.C[C@]12CC[C@H]3[C@@H](CC=C4CCCC[C@@]43C)[C@@H]1C[C@@H](F)C2=O.Cc1cccc(C)c1NC1=NCCCS1.FC(F)OC(Cl)C(F)(F)F>>C=C(C)[C@H]1CC=C(C)CC1.CCCCCCCCCCCCCC(=O)OC(C)C,,CCO,,,,test
US05348870,CC(C)O.C[C@@H]1C(=O)O[C@@H](C(Cl)(Cl)Cl)O[C@H]1C>>CC(C)OC(=O)[C@@H](C)[C@H](C)O,,O,,O=S(=O)(O)O,,test
US05196224,CC(C)=CCCc1ccsc1>>CC(C)CCCc1ccsc1,[Pd],CCO,,,,test
US20130116235A1,COc1ncc(-c2ccnc(N3CCn4c(cc5c4CC(C)(C)C5)C3=O)c2CO)cc1Nc1ccc(N2CCN(C(=O)OC(C)(C)C)C[C@@H]2C)cn1>>C[C@H]1CNCCN1c1ccc(Nc2cc(-c3ccnc(N4CCn5c(cc6c5CC(C)(C)C6)C4=O)c3CO)c[nH]c2=O)nc1,,C1COCCO1,Cl,,,test
US20050239802A1,CCC(=O)Cl.COC(=O)c1cc(C2=C(c3cc(Cl)ccc3OCc3ccccc3)CCC2)ccc1N>>CCC(=O)Nc1ccc(C2=C(c3cc(Cl)ccc3OCc3ccccc3)CCC2)cc1C(=O)OC,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20070281918A1,COc1nc2c(cc1[N+](=O)[O-])C(C)CN(C(=O)C(F)(F)F)CC2>>COc1nc2c(cc1[N+](=O)[O-])C(C)CNCC2,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US04963566,C1COCCN1.CCN1CC(C(=O)O)Cc2cccc(CSc3nc4ccccc4[nH]3)c21>>CCN1CC(C(=O)N2CCOCC2)Cc2cccc(CSc3nc4ccccc4[nH]3)c21,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US20140179682A1,O=C1Nc2cc(Br)ccc2C1=O.OO>>Nc1cc(Br)ccc1C(=O)O,,[Na+],[OH-],,,test
US20160016937A1,Clc1ncc(Br)cn1.OB(O)c1ccccc1C(F)(F)F>>FC(F)(F)c1ccccc1-c1cnc(Cl)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090163508A1,Cc1noc(NC(=O)OCC(Cl)(Cl)Cl)c1C.Fc1ccc(-c2nccc(N3CCNCC3)n2)c(F)c1>>Cc1noc(NC(=O)N2CCN(c3ccnc(-c4ccc(F)cc4F)n3)CC2)c1C,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US06342503B1,Brc1nccs1.CCN(c1nc(C)cc(C(=O)OC)n1)c1ccc(C(C)C)cc1Br>>CCN(c1nc(C)cc(C(=O)c2nccs2)n1)c1ccc(C(C)C)cc1Br,,C1CCOC1,CCOC(C)=O,[Li]CCCC,O=C([O-])O.[Na+],test
US20120322785A1,NC(=O)C1CC1.Oc1c(-c2ccccc2Cl)ncc2cc(Cl)ncc12>>O=C(Nc1cc2cnc(-c3ccccc3Cl)c(O)c2cn1)C1CC1,,C1CCOC1,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070135456A1,C=CCn1cnc2[nH]c(=O)[nH]c(=O)c21.CCCCI>>C=CCn1cnc2c1c(=O)[nH]c(=O)n2CCCC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040206933A1,CCCCCCCCOOB(O)c1cccc(F)c1F.OCCCCCCOc1ccc(-c2ccc(Br)cc2)cc1>>CCCCCCCCOc1ccc(-c2ccccc2-c2ccc(OCCCCCCO)cc2)c(F)c1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20160244437A1,Cc1cc(S(=O)(=O)N(C)C)ccc1-c1cccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)c1.Cl>>Cc1cc(S(=O)(=O)N(C)C)ccc1-c1cccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)c1.Cl,,C1COCCO1,,CC#N,,test
US20040176361A1,O=c1[nH]c(C2CCCN(Cc3ccccc3)C2)cc2ccccc12>>CN1CCCC(c2cc3ccccc3c(=O)[nH]2)C1,,ClCCl,,CC(Cl)OC(=O)Cl,,test
US04960897,C=C(C)c1cccc(C(F)(F)F)n1.O=C1CCC(=O)N1Cl>>C=C(CCl)c1cccc(C(F)(F)F)n1,,CCCCCC,,c1ccccc1,,test
US20070082890A1,CCOC(=O)Cn1nccn1.NN>>NNC(=O)Cn1nccn1,,CCO,,O,,test
US20070185155A1,BrCCOCc1ccccc1.Cc1ccc(C(O)(c2ccc(C)cc2)C23CCN(CC2)CC3)cc1>>Cc1ccc(C(O)(c2ccc(C)cc2)C23CC[N+](CCOCc4ccccc4)(CC2)CC3)cc1.[Br-],,CC#N,,,,test
US20100087427A1,CC(C)(C)OC(=O)N1C[C@@H](CN(Cc2ccccc2)c2ccc(Cl)cc2)[C@@H](OCc2ccccc2)C1>>Clc1ccc(N(Cc2ccccc2)C[C@@H]2CNC[C@@H]2OCc2ccccc2)cc1,,O,,CC#N,CC#N,test
US20120040985A1,COc1cc(C(C)(C)c2cnc(SCc3c(F)cc(OCCN)cc3F)n2-c2ccc(F)cc2)ccc1Cl.N#C[N-]C#N>>COc1cc(C(C)(C)c2cnc(SCc3c(F)cc(OCCN/C(N)=N/C#N)cc3F)n2-c2ccc(F)cc2)ccc1Cl,,CC(C)O,,Cl,,test
US20110039889A1,O=C(Cl)C(=O)Cl.O=C(O)c1ccc(OCC2CC2)c(Cl)c1>>O=C(Cl)c1ccc(OCC2CC2)c(Cl)c1,,ClCCl,,CN(C)C=O,,test
US20050182072A1,C=O.C[C@H](Nc1cc(-c2nc(N3CC4CC3CN4)c3ccccc3n2)ccn1)c1ccccc1>>C[C@H](Nc1cc(-c2nc(N3CC4CC3CN4C)c3ccccc3n2)ccn1)c1ccccc1,,CO,ClC(Cl)Cl,[BH3-]C#N.[Na+],,test
US20060128712A1,CC(C)(C)OC(=O)N1CCN(c2nc3ccccc3o2)CC1.Cl>>Cl.c1ccc2oc(N3CCNCC3)nc2c1,,C1COCCO1,,,,test
US06080781,O=Cc1ccc2c(c1)OCO2.O=c1ccoc2cc(O)ccc12>>O=C1C(=Cc2ccc3c(c2)OCO3)COc2cc(O)ccc21,,O,,CO,Cl,test
US20040158067A1,Cc1cccc(C(C)C)c1B(O)O.O=[N+]([O-])O>>Cc1c([N+](=O)[O-])ccc(C(C)C)c1B(O)O,,O,,,,test
US20140179680A1,CC(C)[C@@H]1C[C@@H](O)CN1c1nc2cc(C#N)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1.CI>>CO[C@@H]1C[C@@H](C(C)C)N(c2nc3cc(C#N)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C1,,C1CCOC1,,[H-].[Na+],,test
US20030153604A1,COC(=O)c1ccc(-c2cnc(=O)[nH]c2)cc1>>COC(=O)c1ccc(C2CNC(=O)NC2)cc1,[Pd],CN(C)C=O,CO,,,test
US20100317647A1,CCOC(=O)[C@@H]1CC(=O)C[C@H]1C(=O)NC1(C#N)CC1>>CCOC(=O)[C@@H]1CC(O)C[C@H]1C(=O)NC1(C#N)CC1,,C1CCOC1,,[BH4-].[Na+],,test
US20110144336A1,CCOC(=O)C(C)(Cc1ccccc1)NC(=O)CCl.N>>CC1(Cc2ccccc2)NC(=O)CNC1=O,,CCO,,O,,test
US20130090341A1,COC(=O)c1cc(C)ccc1Br.OB(O)c1ccncc1>>COC(=O)c1cc(C)ccc1-c1ccncc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],test
US20150322076A1,COC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C#N)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)c(F)c1>>CC(C)(C#N)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)cc2F)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12,,C1CCOC1,,Cl,[Li+].[OH-],test
US05216026,CCC(C)S(N)(=O)=O.O=C=Nc1ccc(Br)cc1>>CCC(C)S(=O)(=O)NC(=O)Nc1ccc(Br)cc1,,[Na+],[OH-],Cl,,test
US20110034463A1,O=C1C=CC(=C2NCCN2)C=C1[N+](=O)[O-]>>Nc1cc(C2=NCCN2)ccc1O,[Pd],CO,,O=C[O-].[NH4+],,test
US05665718,N.O=C(O)c1ncn2c1[C@@H]1CCN1C(=O)c1ccccc1-2>>NC(=O)c1ncn2c1[C@@H]1CCN1C(=O)c1ccccc1-2,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US05877199,O=C(O)CC1CCc2c(n(Cc3ccccc3)c3ccccc23)S1.[N-]=[N+]=C(c1ccccc1)c1ccccc1>>O=C(CC1CCc2c(n(Cc3ccccc3)c3ccccc23)S1)OC(c1ccccc1)c1ccccc1,,CCOC(C)=O,,,,test
US04728653,CO.Cc1cn(-c2cc(C#N)c(N)c(C(F)(F)F)c2)c(C)n1>>Cc1cn(-c2cc(C=O)c(N)c(C(F)(F)F)c2)c(C)n1,,C1CCOC1,Cc1ccccc1,CC(C)C[Al+]CC(C)C.[H-],,test
US20040142921A1,BrCCBr.COC(=O)C(Cc1ccc(O)cc1)NC(C)=CC(=O)c1ccccc1>>COC(=O)C(Cc1ccc(OCCBr)cc1)NC(C)=CC(=O)c1ccccc1,,CCO,,[K+].[OH-],,test
US04647558,CCN1CCN(C(=O)NC(C(=O)NC2(S(C)=O)C(=O)NC2C)c2ccccc2)C(=O)C1=O.N>>CCN1CCN(C(=O)NC(C(=O)NC2(N)C(=O)NC2C)c2ccccc2)C(=O)C1=O,,C1COCCO1,,,,test
US20080319188A1,Nc1ccc(Oc2ccnc(NC(=O)N3CCOCC3)c2)cc1.O=C(O)C1(C(=O)Nc2ccc(F)cc2)CC1>>O=C(Nc1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2)ccn1)N1CCOCC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04841067,COCC(O)[C@H](CC(C)C)NC(=O)OCc1ccccc1.Cl>>COCC(O)[C@@H](N)CC(C)C.Cl,[Pd],CO,,,,test
US20090054463A1,Ic1cccnc1.NCCC(c1ccccc1)c1ccccc1>>c1ccc(C(CCNc2cccnc2)c2ccccc2)cc1,[Cu]I,CCOC(C)=O,CS(C)=O,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US20160052923A1,CC(Cl)Br.N#CCc1ccccc1>>N#CC1(c2ccccc2)CC1,,C1CCOC1,CS(C)=O,[H-].[Na+],,test
US20090312338A1,CCOC(=O)C1CC(NC(=O)OC(C)(C)C)CC1CC>>CCC1CC(NC(=O)OC(C)(C)C)CC1C(=O)O,,C1CCOC1,ClCCl,[Na+].[OH-],,test
US20110319378A1,CC(C)[Si](OCCC1(CCN2CCCC2)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O)(C(C)C)C(C)C>>O=C1N(CC2CC2)[C@H](c2ccc(Cl)cc2)[C@@H](c2cccc(Cl)c2)CC1(CCO)CCN1CCCC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080234260A1,Cc1cc(C(=O)N2CCOCC2)sc1Br>>Cc1cc(CN2CCOCC2)sc1Br,,CO,,C1CCOC1,[Na+].[OH-],test
US20050070521A1,CC(=O)N1CC(O)C1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(=O)N1CC(OC(c2ccccc2)(c2ccccc2)c2ccccc2)C1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US06255323B1,O=C1c2ccccc2C(=O)N1CCN1CCC(NC(c2ccccc2)c2ccccc2)CC1>>NCCN1CCC(NC(c2ccccc2)c2ccccc2)CC1,,CCO,,NN,O,test
US20150361065A1,COc1ccc(-c2sc3cc(OC)ccc3c2Oc2ccc(/C=C/C(=O)OC(C)(C)C)cc2)cc1>>COc1ccc(-c2sc3cc(OC)ccc3c2Oc2ccc(C=CC(=O)OC(C)(C)C)cc2)cc1,[Pd],ClCCl,,CO,,test
US20140329799A1,C1COCCN1.COc1cc(N[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)nc(S(C)(=O)=O)n1>>COc1cc(N[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)nc(N2CCOCC2)n1,,CC#N,,,,test
US20080280925A1,CC(C)(C)OC(=O)N1CCC(I)CC1.CCOC(=O)c1cc(C(F)(F)F)n[nH]1>>CCOC(=O)c1cc(C(F)(F)F)nn1C1CCN(C(=O)OC(C)(C)C)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080119466A1,COC(OC)N(C)C.Cl.Nc1ncnc2c1ncn2-c1ccc(NC(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)cc1>>CN(C)C=Nc1ncnc2c1ncn2-c1ccc(NC(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)cc1.Cl,,c1ccncc1,,,,test
US20100016279A1,CC(C)(c1ccc(F)cc1)N1CCNCC1.FC(F)(F)c1nnc2ccc(Cl)nn12>>CC(C)(c1ccc(F)cc1)N1CCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04472435,NO.O=C1CN=C(c2ccccc2F)c2cc([N+](=O)[O-])ccc2N1>>NCC(=O)Nc1ccc([N+](=O)[O-])cc1C(=NO)c1ccccc1F,,ClCCl,c1ccncc1,Cl,,test
US20090281311A1,Brc1ccc(-c2ccccc2)cc1.Brc1ccc(-c2nc(-c3ccc(-c4ccccc4)cc3)nc(-c3ccc(-c4ccccc4)cc3)n2)cc1>>c1ccc(-c2ccc(-c3ccc(-c4nc(-c5ccc(-c6ccccc6)cc5)nc(-c5ccc(-c6ccccc6)cc5)n4)cc3)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,CCCCCC,[Li]CCCC,test
US06013830,Br[Mg]C1CCCCC1.CCOC(=O)C(=O)OCC>>CCOC(=O)C(=O)C1CCCCC1,,C1CCOC1,CCOCC,,,test
US20110118251A1,CCOC(=O)c1c[nH]nc1C.FN1C=CC=CC1Br>>CCOC(=O)c1cn(-c2ncccc2Br)nc1C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130096134A1,CCCc1nc2cc(F)ccc2cc1[C@H](C)N1C(=O)c2ccccc2C1=O>>CCCc1nc2cc(F)ccc2cc1[C@H](C)N,,CCO,,NN,O,test
US20160137636A1,O=C1CCC(=O)N1Br.O=c1[nH]ccc2ccc(SCc3ccccc3)cc12>>O=c1[nH]cc(Br)c2ccc(SCc3ccccc3)cc12,,O,,CC#N,,test
US07179823B1,CCOC(=O)CCc1cn(Cc2ccc(O)cc2)nc1OCC.CCOc1cccc2nc(CCl)cn12>>CCOC(=O)CCc1cn(Cc2ccc(OCc3cn4c(OCC)cccc4n3)cc2)nc1OCC,,CN(C)C=O,,O,[H-].[Na+],test
US04729994,COc1ccc(CCN(C)[C@@H](C)CO)cc1OC.Cl.O=S(Cl)Cl>>COc1ccc(CCN(C)[C@@H](C)CCl)cc1OC.Cl,,ClC(Cl)Cl,,,,test
US20100331293A1,CCCI.Cc1c(N2CCNC(=O)C2)nc2cc(F)cc(F)c2c1Br>>CCCN1CCN(c2nc3cc(F)cc(F)c3c(Br)c2C)CC1=O,,C1CCOC1,,[H-].[Na+],,test
US05310735,C[Si](C)(C)Cl.O=C(O)[C@@H]1C[C@@H](O)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1>>C[Si](C)(C)O[C@@H]1C[C@@H](C(=O)O)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1,,CC#N,,CCN(CC)CC,,test
US05082856,CCCCCCCCCCCCC(=O)c1cc(C2(OCC)OCCSSO2)c[nH]1>>CCCCCCCCCCCCCc1cc(C(=O)OCC)c[nH]1,[Ni],CCO,,,,test
US20070010532A1,CC(=O)Cl.CSC1=N/C(=N\C(=O)c2cnccc2C(F)(F)F)NC1(C)C>>CSC1=N/C(=N\C(=O)c2cnccc2C(F)(F)F)N(C(C)=O)C1(C)C,,ClCCl,O,CCN(CC)CC,CCOC(C)=O,test
US20070112033A1,CC(=O)c1cccc(NS(=O)(=O)c2ccccc2)c1.O=S(=O)(Cl)Cl>>O=C(CCl)c1cccc(NS(=O)(=O)c2ccccc2)c1,,ClCCl,,CO,,test
US20110034450A1,COC(=O)CCC1CCCC(NC(=O)C(c2ccc(CN3N=C(c4ccccc4)OCC3=O)cc2)C(C)C)C1>>CC(C)C(C(=O)NC1CCCC(CCC(=O)O)C1)c1ccc(CN2N=C(c3ccccc3)OCC2=O)cc1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20160157491A1,Cc1cccc(C)c1NC(=S)NN.O=Cc1ccc2c(c1)CCc1c-2cnn1-c1ccc(OC(F)(F)F)cc1>>Cc1cccc(C)c1NC(=S)N/N=C/c1ccc2c(c1)CCc1c-2cnn1-c1ccc(OC(F)(F)F)cc1,,CCO,,,,test
US20110183989A1,O=C1[C@@H]2CNCCN2C(=O)N1[C@H]1C[C@@H]1c1ccccc1.O=C=Nc1cccc(Cl)c1Cl>>O=C(Nc1cccc(Cl)c1Cl)N1CCN2C(=O)N([C@H]3C[C@@H]3c3ccccc3)C(=O)[C@@H]2C1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20030013713A1,COc1ccc(C(=O)OC2CCCC2)nc1OC1CCCC1>>COc1ccc(C(=O)O)nc1OC1CCCC1,,CO,O,[K+].[OH-],,test
US20140296249A1,O=C1c2ccccc2C(=O)N1CCC(O)CN1CCN(c2cccc(Cl)c2Cl)CC1>>NCCC(O)CN1CCN(c2cccc(Cl)c2Cl)CC1,,CCO,,NN,,test
US04362740,NS(=O)(=O)c1ccc2c(c1)C(=O)C1(CCOC1=O)S2>>NS(=O)(=O)c1ccc2c(c1)C(=O)C1(CC1)S2,,CCO,,,,test
US20140088101A1,COC(=O)CN(Cc1c(C(=O)OC)cc(Br)c(=O)n1[C@@H](C)c1ccccc1)S(=O)(=O)c1ccc(C)cc1>>COC(=O)c1ncc2c(cc(Br)c(=O)n2[C@@H](C)c2ccccc2)c1O,,CO,,Cl,C[O-].[Na+],test
US05437812,CCCCCCCCBr.Oc1ccc(-c2ncc(OCc3ccccc3)cn2)cc1>>CCCCCCCCOc1ccc(-c2ncc(O)cn2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20090181934A1,O=C(Nc1cccnc1)N[C@@H]1CCN(c2nc(NCC(c3ccccc3)c3ccccc3)c3ncn([C@@H]4C[C@H](NC(=O)OCc5ccccc5)[C@@H](O)[C@H]4O)c3n2)C1>>N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(N4CC[C@@H](NC(=O)Nc5cccnc5)C4)nc32)[C@H](O)[C@@H]1O,[Pd],CCO,,O=C(O)C(F)(F)F,,test
US20150307522A1,Cc1nc(C=O)cs1.O=C(O)CC(=O)O>>Cc1nc(/C=C/C(=O)O)cs1,,c1ccncc1,,C1CCNCC1,Cl,test
US20120214791A1,CCOC=NNC(=O)OC.COc1ccc(CN)cc1>>COC(=O)NN=CNCc1ccc(OC)cc1,,CCO,,,,test
US20100016279A1,C1CCOC1.CC(C)OC(=O)/N=N/C(=O)OC(C)C.Oc1ccc(C2(O)CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1.Oc1ccc(C2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1>>Cn1nccc1CCOc1ccc(C2(O)CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20030036557A1,CS(=O)(=O)c1ccc(N2CC(O)(C(F)(F)F)N=C2c2ccncc2)cc1>>CS(=O)(=O)c1ccc(-n2cc(C(F)(F)F)nc2-c2ccncc2)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20060142306A1,CC(C)(C)OC(=O)NCCCCc1ccc(OCCN(C[C@@H](O)[C@@H](O)CO)C[C@@H](O)[C@@H](O)CO)cc1>>NCCCCc1ccc(OCCN(C[C@@H](O)[C@@H](O)CO)C[C@@H](O)[C@@H](O)CO)cc1,,CCO,,Cl,,test
US20050209290A1,FC(F)(F)Oc1ccc(C=Cc2nc(CCl)co2)cc1.Oc1ccc(COCCn2ccnn2)c(F)c1>>Fc1cc(OCc2coc(/C=C/c3ccc(OC(F)(F)F)cc3)n2)ccc1COCCn1ccnn1,,CN(C)C=O,,O,[H-].[Na+],test
US20120289551A1,Nc1cc(-c2cc(C(F)(F)F)nn2-c2ccc(F)cc2)ccn1.O=C=NC(=O)c1ccccc1>>NC(=O)Nc1cc(-c2cc(C(F)(F)F)nn2-c2ccc(F)cc2)ccn1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20090023729A1,BrC(Br)(Br)Br.Cc1ccc(OCc2ccccc2)c(CO)n1>>Cc1ccc(OCc2ccccc2)c(CBr)n1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US06673968B1,Cc1cc(S(C)(=O)=O)c(S(C)(=O)=O)cc1C(=O)Cl.N=C(N)N>>Cc1cc(S(C)(=O)=O)c(S(C)(=O)=O)cc1C(=O)NC(=N)N,,CN(C)C=O,,O,,test
US20080207721A1,CSc1ccc([C@@H](Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)[C@H](C)N)cc1.O=S(=O)(Cl)C1CC1>>CSc1ccc([C@@H](Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)[C@H](C)NS(=O)(=O)C2CC2)cc1,,CC#N,,CCN(CC)CC,,test
US05324747,CCCCCCCCCCNCCCCCCCCCC.O=C(Cl)c1cccc([N+](=O)[O-])c1>>CCCCCCCCCCN(CCCCCCCCCC)C(=O)c1cccc([N+](=O)[O-])c1,,ClCCl,,CCN(CC)CC,O,test
US20020037889A1,COC(=O)C1(c2cccnc2)CC1>>OCC1(c2cccnc2)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US08263606B2,CN1C(=O)C2(COc3cc4c(cc32)OCCO4)c2c(C#N)cccc21.OO>>CN1C(=O)C2(COc3cc4c(cc32)OCCO4)c2c(C(N)=O)cccc21,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20150258074A1,O=Cc1nc(Cl)cc2c1c(OCc1ccccc1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>OCc1nc(Cl)cc2c1c(OCc1ccccc1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1,,ClCCl,,CO,[BH4-].[Na+],test
US04859692,COC(=O)c1ccc(CN2CCOc3ccc([N+](=O)[O-])cc32)c(OC)c1>>COC(=O)c1ccc(CN2CCOc3ccc(N)cc32)c(OC)c1,[Pd],CCOC(C)=O,,[H][H],,test
US20080171741A1,COC(=O)c1sc(-c2ccc(Cl)cc2)cc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1cc(-c2ccc(Cl)cc2)sc1C(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20060160794A1,Clc1ccccc1C1CCCNC1.O=C(O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-c1ccncc1>>O=C(c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-c1ccncc1)N1CCCC(c2ccccc2Cl)C1,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20080194618A1,BrCCCCOc1ccccc1.OC(c1ccccc1)(c1ccccc1)C12CCN(CC1)C2>>OC(c1ccccc1)(c1ccccc1)C12CC[N+](CCCCOc3ccccc3)(CC1)C2.[Br-],,CC#N,,,,test
US05346880,CCCCC(Sc1nc(OC)cc(OC)n1)C(=O)OC>>CCCCC(CO)Sc1nc(OC)cc(OC)n1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090259049A1,CC(C)(C)O.COc1nn2ccsc2c1C(=O)O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COc1nn2ccsc2c1NC(=O)OC(C)(C)C,,C1COCCO1,,CCN(CC)CC,,test
US20080255117A1,C#Cc1ccc(C(=O)NC)cc1.COc1ccc(Br)cc1S(=O)(=O)N[C@H](Cc1c[nH]c2ccccc12)C(C)(C)O>>CNC(=O)c1ccc(C#Cc2ccc(OC)c(S(=O)(=O)N[C@H](Cc3c[nH]c4ccccc34)C(C)(C)O)c2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,CCO,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20150126490A1,CC(C)(C)[Si](C)(C)OC1C=C(c2cnc(N)cn2)CCC1>>CC(C)(C)[Si](C)(C)O[C@H]1CCC[C@@H](c2cnc(N)cn2)C1,[Pd],CO,,,,test
US20140275152A1,CCOC(=O)C1=C(c2ccnn2C(C)C)COCC1>>CC(C)n1nccc1C1=C(CO)CCOC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150165063A1,C=CCOC(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)Nc1ccc(COC(=O)Nc2cc(OCCCCCC(=O)N3C[C@@H](CCl)c4c3cc(OC(=O)N3CCN(C)CC3)c3ccccc43)c(OC)cc2C(=O)N2CCC[C@H]2COC(C)=O)cc1>>C=CCOC(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)Nc1ccc(COC(=O)Nc2cc(OCCCCCC(=O)N3C[C@@H](CCl)c4c3cc(OC(=O)N3CCN(C)CC3)c3ccccc43)c(OC)cc2C(=O)N2CCC[C@H]2CO)cc1,,CO,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20100273767A1,CC(C)(C)OC(=O)N1CCN2c3ccccc3NC(=O)CC2C1>>O=C1CC2CNCCN2c2ccccc2N1,,ClCCl,,C1COCCO1,Cl,test
US20010034343A1,COC(=O)c1cc(OC)c2c(c1)OCCO2>>COc1cc(C(=O)O)cc2c1OCCO2,,C1CCOC1,,[Li+].[OH-],,test
US20150329523A1,COCCOCCOCCN(C)c1cc(OC)cc([N+](=O)[O-])c1>>COCCOCCOCCN(C)c1cc(N)cc(OC)c1,[Fe],CC(C)O,O,[Cl-].[NH4+],,test
US20090048295A1,CCc1cccc(CC)c1B(O)O.O=C1CCCc2nc(Cl)ccc21>>CCc1cccc(CC)c1-c1ccc2c(n1)CCCC2=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20150299189A1,Fc1cccc(CBr)c1.O=[N+]([O-])c1ccc2[nH]ccc2c1>>O=[N+]([O-])c1ccc2c(ccn2Cc2cccc(F)c2)c1,,CN(C)C=O,,O,CC(C)(C)[O-].[K+],test
US20110212937A1,C1O[C@@H]2CN[C@H]1C2.Fc1ccc(C2CCc3c(Cl)nc(Cl)nc32)cc1>>Fc1ccc(C2CCc3c2nc(Cl)nc3N2C[C@@H]3C[C@H]2CO3)cc1,,CO,,CCN(C(C)C)C(C)C,Cl,test
US20150038437A1,C=CCc1c(O)c(C(=O)O)c(=O)n(Cc2ccc(OC)cc2OC)c1-c1ccc2[nH]c(CN(C)C)cc2c1>>CCCc1c(O)c(C(=O)O)c(=O)n(Cc2ccc(OC)cc2OC)c1-c1ccc2[nH]c(CN(C)C)cc2c1,[Pd],CCOC(C)=O,,,,test
US20060004069A1,CCOC(=O)c1cnn(-c2ccccc2)c1-c1ccccc1>>OCc1cnn(-c2ccccc2)c1-c1ccccc1,,C1CCOC1,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20020183361A1,BrC1=CCCCC1.CC[C@H](C)[C@@H](C=O)NS(=O)(=O)c1ccc(Cl)s1>>CC[C@H](C)[C@H](NS(=O)(=O)c1ccc(Cl)s1)[C@@H](O)C1C=CCCC1,,C1CCOC1,,[Mg],[Cl-].[NH4+],test
US20140073623A1,CC(C)(C)OC(=O)N1CCC[C@@H]1CO.COC(=O)c1c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)ccc(Br)c1O>>COC(=O)c1c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)ccc(Br)c1OC[C@H]1CCCN1C(=O)OC(C)(C)C,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(Br)cc23)cc1.Cc1cc(N)cc2cn[nH]c12>>Cc1cc(Nc2nc3ccc(Br)cc3c3c[nH]nc23)cc2cn[nH]c12,C1COCCO1,CO,,Cl,,test
US20030216463A1,Brc1ccc(OCCN2CCCCC2)cc1.CC(C)(C)[Si](C)(C)Oc1ccc2c(c1)OCc1c-2c(=O)oc2cc(O[Si](C)(C)C(C)(C)C)ccc12.C[Mg]Br>>CC(O)(C1=C(c2ccc(O[Si](C)(C)C(C)(C)C)cc2O)COc2cc(O[Si](C)(C)C(C)(C)C)ccc21)c1ccc(OCCN2CCCCC2)cc1,,C1CCOC1,,[Li]CCCC,,test
US20160075713A1,CCOC(=O)C(F)(F)Br.Clc1ccc(I)cc1>>CCOC(=O)C(F)(F)c1ccc(Cl)cc1,,CS(C)=O,O,,,test
US20030087908A1,COc1cc(N)cc(OC)c1OC.Clc1ncnc(-c2cccnc2Cl)n1>>COc1cc(Nc2ncnc(-c3cccnc3Cl)n2)cc(OC)c1OC,,CCN(CC)CC,,,,test
US20020151715A1,CC(=O)O.CC(C)(C)c1cccc(N)c1.CCOC(=O)C[N+](=O)[O-].CCOC(OCC)OCC>>CC(C)(C)c1cccc(-n2cnc(CO)c2)c1,[Fe],,,,,test
US20150080438A1,COc1ccc2c(c1)CCCC(c1cccnc1)=C2C#CCCCCO>>COc1ccc2c(c1)CCCC(c1cccnc1)=C2CCCCCCO,[Pd],C1CCOC1,,,,test
US20070049618A1,Cc1ccc(N=C=O)cc1Cl.NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O>>Cc1ccc(NC(=O)NCc2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)cc1Cl,,c1ccncc1,,CCN(C(C)C)C(C)C,Cl,test
US04484993,CCOC(=O)C(F)(F)F.O=C(CBr)C(F)(F)F>>O=C(CC(=O)C(F)(F)F)C(F)(F)F,[Zn],CN(C)C=O,,C1CCOC1,,test
US20070117988A1,BrC(c1ccccc1)c1ccccc1.O[C@H]1CCNC1>>O[C@H]1CCN(C(c2ccccc2)c2ccccc2)C1,,CC#N,,CCN(CC)CC,,test
US20050032873A1,N#Cc1ccc2[nH]cc(CCCBr)c2c1.NC(=O)c1ccc(F)c2c1CC(N)CO2>>N#Cc1ccc2[nH]cc(CCCNC3COc4c(F)ccc(C(N)=O)c4C3)c2c1,,CS(C)=O,O,CCN(C(C)C)C(C)C,,test
US20130109566A1,FC(F)(F)CCBr.O=C(O)CCS>>O=C(O)CCSCCC(F)(F)F,,CO,,[K+].[OH-],,test
US20060074111A1,COC(=O)COc1ccc(CBr)cc1C.CSCCNc1cccc(-c2ccc(C(F)(F)F)cc2)c1>>COC(=O)COc1ccc(CN(CCSC)c2cccc(-c3ccc(C(F)(F)F)cc3)c2)cc1C,,CC#N,,CCN(C(C)C)C(C)C,,test
US20110046108A1,O=C(O)c1cccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)c1.O=S(Cl)Cl>>O=C(Cl)c1cccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)c1,CN(C)C=O,,,,,test
US20130085164A1,CCOC(=O)c1ccc(-c2ccc(C=O)nc2)cc1.CC[Mg]Br>>CCOC(=O)c1ccc(-c2ccc(C(O)CC)nc2)cc1,,C1CCOC1,,CCOCC,,test
US04868099,CCCCCCCCCCCCCCCCS(=O)(=O)Cl>>CCCCCCCCCCCCCCCCS(=O)O,,CO,,NN,O,test
US20040204448A1,C1COCCN1.CCOc1cc(C(CC(=O)O)N2Cc3cccc(NC(C)=O)c3C2=O)ccc1OC(F)F>>CCOc1cc(C(CC(=O)N2CCOCC2)N2Cc3cccc(NC(C)=O)c3C2=O)ccc1OC(F)F,,C1CCOC1,,O,O=C(n1ccnc1)n1ccnc1,test
US20130324758A1,O=C=O.O=O.OCC(O)CO>>C=CC=O.O=C=O.O=O,,O,,,,test
US20090136473A1,Brc1cccc(I)c1.COc1ccc(F)c(B(O)O)c1>>COc1cccc(F)c1-c1cccc(Br)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20110263598A1,COS(=O)(=O)OC.COc1ccc2c(c1)CC(=O)N2>>COc1ccc2c(c1)CC(=O)N2C,,Cc1ccccc1,,[H-].[Na+],,test
US05068356,CC(C)(C)c1cc(CCC(=O)NN)cc(C(C)(C)C)c1O.O=C1C=CC(=O)O1>>CC(C)(C)c1cc(CCC(=O)NN2C(=O)C=CC2=O)cc(C(C)(C)C)c1O,,O,,Cc1ccccc1C,,test
US20120238582A1,CCCCBr.CCOC(=O)Cc1ccc([N+](=O)[O-])cc1>>CCCCC(C(=O)OCC)c1ccc([N+](=O)[O-])cc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20110092479A1,CC(C)(C)[Si](C)(C)OCC#Cc1n[nH]c2ncc([N+](=O)[O-])cc12>>CC(C)(C)[Si](C)(C)OCCCc1n[nH]c2ncc(N)cc12,[Pd],CCO,CCOC(C)=O,,,test
US05502054,O=C(Cl)C(=O)Cl.O=C(O)CCCc1ccc(Cl)cc1Cl>>O=C(Cl)CCCc1ccc(Cl)cc1Cl,CN(C)C=O,CCOCC,,,,test
US20130245254A1,Cc1cc(B2OC(C)(C)C(C)(C)O2)cc(N)c1N.N#CBr>>Cc1cc(B2OC(C)(C)C(C)(C)O2)cc2nc(N)[nH]c12,,CO,,,,test
US20070149570A1,CC(C)[Si](Oc1ccc(Br)cc1C=O)(C(C)C)C(C)C.N#Cc1ccc(B(O)O)cc1>>N#Cc1ccc(-c2ccc(O)c(C=O)c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20060128793A1,CCNCC.COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CC[C@H](O)[C@@]2(C)C[C@H]1OC(C)=O>>CCN(/C=C1/C(=O)O[C@H](COC)[C@@]2(C)C1=C(O)C(=O)C1=C2[C@H](O)C[C@@]2(C)[C@H]1CC[C@@H]2O)CC,,CO,,,,test
US05331084,C1=CCC=C1.C=CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.CC(C)(C)OO>>FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CC1CC2CC1C1OC21,,Cc1ccccc1,,,,test
US20120053173A1,COCc1n[nH]cc1C(=O)OC.FC(F)(F)c1ccnc(Cl)c1>>COCc1nn(-c2cc(C(F)(F)F)ccn2)cc1C(=O)OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110245272A1,O=C(CCl)N1CCCCC1.c1cnc2[nH]c3c(c2c1)C1CCCN1CC3>>O=C(Cn1c2c(c3cccnc31)C1CCCN1CC2)N1CCCCC1,,CN(C)C=O,,[H-].[Na+],,test
US20100311778A1,CC1(C)CC(N)c2ccccc2O1.CCN(CC)CC.COc1ccc2[nH]c(C)c(CC(=O)O)c2c1.Cl>>COc1ccc2[nH]c(C)c(CC(=O)NC3CC4(CCC4)Oc4ccc(Cl)cc43)c2c1,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20150210641A1,COc1cc(F)ccc1-c1ccc(C(O)c2ccncc2)cc1.CS(=O)(=O)Cl>>COc1cc(F)ccc1-c1ccc(C(OS(C)(=O)=O)c2ccncc2)cc1,,ClCCl,,CCN(CC)CC,,test
US20120329877A1,CC(C)COC1=CC(=O)C(Cc2cccc(CCN=[N+]=[N-])c2)C1.O=S(=O)(Cl)c1ccc(Cl)cc1>>CC(C)COC1=CC(=O)C(Cc2cccc(CCNS(=O)(=O)c3ccc(Cl)cc3)c2)C1,[Pd],CCOC(C)=O,CO,[H][H],,test
US20090291917A1,COCOCc1cc(O)ccc1Br.N#Cc1ccc(CBr)cc1>>COCOCc1cc(OCc2ccc(C#N)cc2)ccc1Br,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070032485A1,CC[C@@H]1C[C@H](Nc2ncc(Br)cn2)c2nc(OC)ccc2N1C(=O)OC(C)(C)C.FC(F)(F)c1cc(CBr)cc(C(F)(F)F)c1>>CC[C@@H]1C[C@H](Nc2ncc(Br)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)c2nc(OC)ccc2N1C(=O)OC(C)(C)C,,CN(C)C=O,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20150099730A1,COC(=O)Cl.O=C1NC(c2ccc(Br)cc2)=NC12CCNCC2>>COC(=O)N1CCC2(CC1)N=C(c1ccc(Br)cc1)NC2=O,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US05824802,C=O.CCn1ncc(C(=O)c2ccc(S(C)(=O)=O)c(NCCCO)c2Cl)c1O>>CCn1ncc(C(=O)c2ccc(S(C)(=O)=O)c(N3CCCOC3)c2Cl)c1O,,CCOCC,ClCCl,,,test
US20090018103A1,CN(C(=O)OCC[Si](C)(C)C)C(CN)CC1(O)CCCCC1.C[Si](C)(C)Cl.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CN(C(=O)OCC[Si](C)(C)C)C(CNC(=O)Oc1ccc([N+](=O)[O-])cc1)CC1(O[Si](C)(C)C)CCCCC1,,ClCCl,,CCN(CC)CC,,test
US04686291,BrBr.CC(=O)C(C)(C)Cc1ccccc1>>CC(C)(Cc1ccccc1)C(=O)CBr,,ClC(Cl)Cl,,,,test
US04130649,CCOc1cc2c(=O)cc(C(=O)O)n(CC)c2ccc1=O>>CCOc1cc2c(=O)cc(C(=O)O)[nH]c2ccc1=O,,Cl,,,,test
US20160083365A1,COc1nc(N[C@@H](C)c2cc3cc(Cl)c(Br)cc3[nH]c2=O)ncc1C#N.OB(O)C1CC1>>COc1nc(N[C@@H](C)c2cc3cc(Cl)c(C4CC4)cc3[nH]c2=O)ncc1C#N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20100056512A1,CNC(=O)c1c(C)oc2cc(N)ccc12.Clc1ccnc(Cl)n1>>CNC(=O)c1c(C)oc2cc(Nc3ccnc(Cl)n3)ccc12,,CCO,,CCN(CC)CC,,test
US05070082,O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O.O=P(O)(O)O>>O=C(O)c1cn(C2CC2)c2cc(N3CCN(P(=O)(O)O)CC3)c(F)cc2c1=O,,O=P([O-])([O-])[O-],,,,test
US20010031788A1,CCOC(=O)CC(N)c1cccc(OC)c1.O=S(=O)(Cl)c1ccccc1>>CCOC(=O)CC(NS(=O)(=O)c1ccccc1)c1cccc(OC)c1,,CCN(CC)CC,,Cl,,test
US20080081818A1,CC(=O)C(Br)C(=O)OC(C)(C)C.CC(C)c1ccc(CNC(=O)[C@H]2CN(C(N)=S)CCN2S(=O)(=O)c2ccc(C(F)(F)F)cc2)cc1>>Cc1nc(N2CCN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)[C@@H](C(=O)NCc3ccc(C(C)C)cc3)C2)sc1C(=O)OC(C)(C)C,,CC#N,,,,test
US20140302988A1,CCn1nc(-c2ccc(Cl)cc2)nc1CC(=O)O.O=C(Cl)C(=O)Cl>>CCn1nc(-c2ccc(Cl)cc2)nc1CC(=O)Cl,,ClCCl,,CN(C)C=O,,test
US05157041,CC(C)CCN1CCC[C@]1(C(N)=O)C(=O)OCc1ccccc1>>CC(C)CCN1CCC[C@H]1C(N)=O,[Pd],CCO,,N#N,,test
US20060084645A1,CCOC(=O)c1ccccc1Nc1cc(-c2ccccc2)nc(N)n1>>Nc1nc(Nc2ccccc2C(=O)O)cc(-c2ccccc2)n1,,CO,,[K+].[OH-],,test
US20140080813A1,O=C(C=C1CCC1)Nc1cccc(F)c1>>O=C1CC2(CCC2)c2c(F)cccc2N1,,Cc1ccccc1,,,,test
US05670511,CC(C)(C)OC(=O)N1CCC(Cl)CC1.Fc1ccc2[nH]cc(C3CCNCC3)c2c1.O=C1NC(=O)c2cccc3cccc1c23.O=C1c2cccc3cccc(c23)C(=O)N1CCCl>>O.O.O.O.O=C1c2cccc3cccc(c23)C(=O)N1CCN1CCC(c2c[nH]c3ccc(F)cc23)CC1,,ClCCCl,,,,test
US20060069087A1,COC(=O)c1ccc2[nH]c(CO)cc2c1>>COC(=O)c1ccc2[nH]c(C=O)cc2c1,O=[Mn]=O,ClC(Cl)Cl,,,,test
US20040127527A1,N#CCc1nc(-c2ccc(Cl)cc2)sc1-c1ccccc1.[N-]=[N+]=[N-]>>Clc1ccc(-c2nc(Cc3nnn[nH]3)c(-c3ccccc3)s2)cc1,,CN(C)C=O,,[Cl-].[NH4+],,test
US20160244437A1,CC(C)(C)OC(=O)NCCN.COc1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1-c1ccc(C(=O)O)cc1C>>COc1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1-c1ccc(C(=O)NCCNC(=O)OC(C)(C)C)cc1C,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050143421A1,CC(=O)NC[C@H]1CN(c2ccc(N3CCC(=O)C(C)(C)C3)c(F)c2)C(=O)O1.[Li]C>>CC(=O)NC[C@H]1CN(c2ccc(N3CCC(C)(O)C(C)(C)C3)c(F)c2)C(=O)O1,,C1CCOC1,,,,test
US20040242890A1,CC[Si](CC)(CC)O[C@@H](CNCc1ccccc1)c1ccc2c(c1)COC(C)(C)O2>>CC1(C)OCc2cc([C@@H](O)CNCc3ccccc3)ccc2O1,,C1CCOC1,CCOCC,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20110257151A1,CS(N)(=O)=O.Cc1ccccc1N1CCN(c2cccc(C3Nc4ccc(C(=O)O)cc4CC3(C)C)c2)CC1>>Cc1ccccc1N1CCN(c2cccc(C3Nc4ccc(C(=O)NS(C)(=O)=O)cc4CC3(C)C)c2)CC1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,[H-].[Na+],test
US05350747,CI.O=C1CCCc2cc(CCN3CCN(c4nsc5ccccc45)CC3)ccc2N1>>CN1C(=O)CCCc2cc(CCN3CCN(c4nsc5ccccc45)CC3)ccc21,,CCCCC,,CN(C)C=O,[H-].[Na+],test
US20090203753A1,O=C(CCOCCc1ccccc1)N(CCNC[C@H](O)c1ccc(OCc2ccccc2)c2[nH]c(=O)sc12)CCc1ccccc1>>O=C(CCOCCc1ccccc1)N(CCNC[C@H](O)c1ccc(O)c2[nH]c(=O)sc12)CCc1ccccc1,[Pd],O=CO,,,,test
US20130324536A1,O=C(/N=C(/NCc1ccc(F)cc1Cl)Nc1cc(C(F)(F)F)n[nH]1)c1ccc(F)c(F)c1.O=C(n1ccnc1)n1ccnc1>>O=C(/N=c1\[nH]c2cc(C(F)(F)F)nn2c(=O)n1Cc1ccc(F)cc1Cl)c1ccc(F)c(F)c1,,C1CCOC1,,,,test
US20080194617A1,Cc1nn(C)c(Cl)c1C=O.c1ccc2[nH]ccc2c1>>Cc1nn(C)c(-n2ccc3ccccc32)c1C=O,,CN(C)C=O,,O,[H-].[Na+],test
US20030186976A1,Cc1c(-c2cc3ccccc3o2)oc(=O)c(C)c1O.O=C(O)c1ccccn1>>Cc1c(-c2cc3ccccc3o2)oc(=O)c(C)c1C(=O)Oc1ccccn1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20090221583A1,CC(C)(C)OC(=O)N1CCNCC1.O=C1OC(=O)c2ccccc21>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccccc2C(=O)O)CC1,,Cc1ccccc1,,,,test
US20070249670A1,COC(=O)[C@@H](NC(=O)c1ccc(-c2cc(F)cc(F)c2)cc1N)C1CCCCC1.Cc1cc(C)c(N=C=O)c(C)c1>>COC(=O)[C@@H](NC(=O)c1ccc(-c2cc(F)cc(F)c2)cc1NC(=O)Nc1c(C)cc(C)cc1C)C1CCCCC1,,c1ccncc1,,CCCCCC,CCOC(C)=O,test
US20060100229A1,CCCn1nc2c(N)nc3ncccc3c2c1CC(C)(C)C#N.OO>>CCCn1nc2c(N)nc3ncccc3c2c1CC(C)(C)C(N)=O,,[Na+],[OH-],,,test
US20110183988A1,Cc1ncc(-c2cnc3[nH]cc(C(=O)c4c(F)ccc(N)c4F)c3c2)cn1.O=S(=O)(Cl)c1ccccc1F>>Cc1ncc(-c2cnc3[nH]cc(C(=O)c4c(F)ccc(NS(=O)(=O)c5ccccc5F)c4F)c3c2)cn1,,C1CCOC1,,c1ccncc1,,test
US20080070924A1,O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CC[C@H](N2CCN(Cc3ccccc3)CC2)C[C@@H]1Cc1ccccc1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCC(N2CCNCC2)CC1Cc1ccccc1,[Pd],CO,,,,test
US20110275784A1,CC(=O)N1[C@@H](C)C(=O)OC[C@H]1c1ccccc1.C[C@H](N)C(=O)OC(C)(C)C>>CC(=O)N(C(CO)c1ccccc1)[C@@H](C)C(=O)N[C@@H](C)C(=O)OC(C)(C)C,,ClCCl,,,,test
US20080171771A1,COc1ccc(C2(c3ccc(O)c(-c4cccc(OC)c4)c3)N=C(NC(=O)OC(C)(C)C)c3ccccc32)cc1.O=C1CCC(=O)N1Br>>COc1ccc(C2(c3ccc(O)c(Br)c3)N=C(NC(=O)OC(C)(C)C)c3ccccc32)cc1,,ClC(Cl)Cl,,,,test
US20130034497A1,CC(C)(C)OC(=O)N[C@@H](C[C@H](CCCO)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.Oc1ccc(I)cc1>>CC(C)(C)OC(=O)N[C@@H](C[C@H](CCCOc1ccc(I)cc1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04945091,O=S(Br)Br.O=c1c(Cl)c(OCc2ccc(Cl)cc2)cnn1CCCO>>O=c1c(Cl)c(OCc2ccc(Cl)cc2)cnn1CCCBr,,O,,ClC(Cl)Cl,,test
US20050049245A1,CNC[C@@H](O)c1ccco1.O=C(NCc1ccc(Cl)cc1)c1cn(CCCOC2CCCCO2)c2sc(CCl)cc2c1=O>>CN(Cc1cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(CCCOC3CCCCO3)c2s1)C[C@@H](O)c1ccco1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140249196A1,COC(=O)[C@H](C)Oc1cccc(C)c1.O=C1CCC(=O)N1Br>>COC(=O)[C@H](C)Oc1cccc(CBr)c1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20050054710A1,CN(C)C=O.CNc1ccc(C(=O)O)cc1[N+](=O)[O-]>>Cn1cnc2cc(C(=O)O)ccc21,[Pd],,,[H][H],,test
US20100197655A1,Cl.N#Cc1cc(S(=O)(=O)NCc2ccccc2)ccc1Oc1ccccc1-c1ccccc1>>N#Cc1cc(S(=O)(=O)Cl)ccc1Oc1ccccc1-c1ccccc1,,ClCCl,,[Na+].[O-]Cl,,test
US20120202785A1,C[C@H](Nc1ncnc(N)c1C#N)c1nc2ccc(F)c(Br)c2n1C.OB(O)c1cccc2[nH]ncc12>>C[C@H](Nc1ncnc(N)c1C#N)c1nc2ccc(F)c(-c3cccc4[nH]ncc34)c2n1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080004302A1,COC(=O)c1cc(NC(=O)OC(C)(C)C)cc(OC)c1>>COc1cc(CO)cc(NC(=O)OC(C)(C)C)c1,,C1CCOC1,CO,Cl,[BH4-].[Na+],test
US05541229,CCCCc1nc2ccc(N(CCCC3CCCCC3)C(=O)NC)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc2ccc(N(CCCC3CCCCC3)C(=O)NC)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04507488,Cc1cnn(C)c1NC(=O)CCl.NCc1ccccc1>>Cc1cnn(C)c1NC(=O)CNCc1ccccc1,,CN(C)C=O,O,,,test
US20130217670A1,CC(=O)O.COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(CN)cc2)c(OCCCO)c(OC)c1>>COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(CNC(C)=O)cc2)c(OCCCO)c(OC)c1,,CN(C)C=O,,O,,test
US20160075722A1,NCC[C@@H]1CN(c2ccc3c(c2)NC(=O)CS3)C(=O)O1.O=Cc1cccc(B(O)O)c1>>O=C1CSc2ccc(N3C[C@@H](CCNCc4cccc(B(O)O)c4)OC3=O)cc2N1,,CN(C)C=O,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20030170394A1,C=C(C)C(=O)OCCCC.C=C(C)C(=O)OCCO.C=C(C)CC(C)(C)C.C=CC(=O)OCCCC.C=CC(=O)OCCCO.C=Cc1ccccc1>>C=C(C)C(=O)OCCCC.C=C(C)C(=O)OCCO.C=C(C)CC(C)(C)C.C=CC(=O)OCCCC.C=CC(=O)OCCCO.C=Cc1ccccc1,,Cc1ccccc1C,,,,test
US20070149446A1,COC(=O)C[C@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@H](NC(=O)OCc1ccccc1)C(C)C>>CC(C)[C@@H](NC(=O)OCc1ccccc1)[C@H](CC(=O)O)O[Si](C(C)C)(C(C)C)C(C)C,,C1CCOC1,CO,[Na+].[OH-],,test
US20150011508A1,Cc1ccc(-c2noc(CCC(C)(C)O)n2)cc1NC(=O)OC(C)(C)C>>Cc1ccc(-c2noc(CCC(C)(C)O)n2)cc1N,,O=C(O)C(F)(F)F,,,,test
US20110201604A1,Cn1c(Nc2nc3ccc(Cl)cc3s2)nc2cc(C(=O)NCC=O)ccc21.FC1(F)CCNCC1>>Cn1c(Nc2nc3ccc(Cl)cc3s2)nc2cc(C(=O)NCCN3CCC(F)(F)CC3)ccc21,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05328637,CCC=O.CCCCCc1ccc(-c2ccc(-c3cccc(F)c3F)cc2)cc1>>CCCCCc1ccc(-c2ccc(-c3ccc(C(O)CC)c(F)c3F)cc2)cc1,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US20070054918A1,CC1CNCCN1.O=[N+]([O-])c1ccc(Cl)nc1>>CC1CN(c2ccc([N+](=O)[O-])cn2)CCN1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140315888A1,CN(C(=O)OC(C)(C)C)C1CN(c2nc3ncc(Cl)cc3nc2Cl)C1.NN>>CN(C(=O)OC(C)(C)C)C1CN(c2nc3ncc(Cl)cc3nc2NN)C1,,CCO,,CCOCC,O,test
US20060223843A1,CC(C)Oc1c(C#N)cnc2ccc(C=O)nc12.O=C1CN(C(=O)OCc2ccccc2)C(NCc2ccc(C(F)(F)F)cc2C(F)(F)F)=N1>>CC(C)Oc1c(C#N)cnc2ccc(C=C3NC(NCc4ccc(C(F)(F)F)cc4C(F)(F)F)=NC3=O)nc12,,CC(C)O,,C1CCNCC1,,test
US20100249187A1,CC(C)(C)C(=O)CBr.O=C(OCC(Cl)(Cl)Cl)N1CCCC(C(=O)O)(C(=O)OCc2ccccc2)C1>>CC(C)(C)C(=O)COC(=O)C1(C(=O)OCc2ccccc2)CCCN(C(=O)OCC(Cl)(Cl)Cl)C1,,CN(C)C=O,,CC(=O)O,O=C([O-])[O-].[K+].[K+],test
US20050020652A1,CCOC(=O)C(C)(O)Cc1ccc(OCc2ccccc2)cc1>>CCOC(=O)C(C)(O)Cc1ccc(O)cc1,[Pd],CCO,,,,test
US04957533,NCc1ccc(C(F)(F)F)cc1.O=C(Cl)c1c(Cl)cccc1Cl>>O=C(NCc1ccc(C(F)(F)F)cc1)c1c(Cl)cccc1Cl,,C1CCOC1,CCN(CC)CC,Cl,,test
US05153210,CC(=O)Cc1ccc(OCc2cc(=O)c(OCc3ccccc3)co2)cc1>>CC(=O)Cc1ccc(OCc2cc(=O)c(O)co2)cc1,,CO,,,,test
US20080161366A1,CNC.O=S1(=O)N(CCCCCBr)c2ccccc2N1c1ccc(F)cc1F>>CN(C)CCCCCN1c2ccccc2N(c2ccc(F)cc2F)S1(=O)=O,,CCO,,,,test
US20030004172A1,CCOC(=O)Cl.COc1ccc(CNC(=O)c2cc3c(=O)n(Cc4ccc(C(=N)NO)cc4)c(=O)n(C)c3s2)cc1>>COc1ccc(CNC(=O)c2cc3c(=O)n(Cc4ccc(-c5noc(=O)[nH]5)cc4)c(=O)n(C)c3s2)cc1,,CN(C)C=O,,O,c1ccncc1,test
US20150209323A1,COc1ccc(Br)cc1-c1cc(=O)c2c(OCc3ccccc3)cccc2o1>>COc1ccc(Br)cc1-c1cc(=O)c2c(O)cccc2o1,,CC(=O)O,O,,,test
US20050054683A1,CC(C)(C)OC(=O)N1CC=C(c2ccc(N)cc2F)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccc(N)cc2F)CC1,[Pd],CO,,,,test
US05338855,COc1cc(CCCC=O)c(OC)c2ccccc12>>COc1cc(CCCCO)c(OC)c2ccccc12,,CCO,,[BH4-].[Na+],,test
US20150045377A1,CN(C)C=O.O=C(NCC(F)(F)F)c1ccoc1I>>O=c1c2ccoc2ncn1CC(F)(F)F,[Cu]I,,,O=C([O-])[O-].[K+].[K+],,test
US05206235,CSc1ccc2c(c1)CCC(I)C(=O)N2.N>>CSc1ccc2c(c1)CCC(N)C(=O)N2,,ClC(Cl)Cl,,,,test
US05196547,NCC12CCCN1CCC2.O=C(O)c1cn2ccccc2n1>>O=C(NCC12CCCN1CCC2)c1cn2ccccc2n1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20080214598A1,CCN(CCc1ccc(Cl)c(C(C)(C)O[SiH2]C(C)(C)C)c1)C(=O)OC(C)(C)C>>CCN(CCc1ccc(Cl)c(CO)c1)C(=O)OC(C)(C)C,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US06150373,CCN(CC)CCOc1ccc(C#N)cc1>>CCN(CC)CCOc1ccc(CN)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04997943,CC(C)(C)OC(=O)N1CC2OC2C1.c1ccc(CNCc2ccccc2)cc1>>CC(C)(C)OC(=O)N1CC(O)C(N(Cc2ccccc2)Cc2ccccc2)C1,,CCO,,,,test
US20160083422A1,CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)NCC(=O)N1c2ccccc2C[C@H]1C(=O)NCc1c[nH]nn1.O=C(O)Cc1nn[nH]n1>>CC[C@H](C)[C@H](NC(=O)Cc1nn[nH]n1)C(=O)NCC(=O)N1c2ccccc2C[C@H]1C(=O)NCc1c[nH]nn1,,CN(C)C=O,,,,test
US20130274255A1,C[Si](C)(C)CCOCn1nc(-c2ccc(Br)cc2)c2c1-c1ccsc1C2.OB(O)/C=C/c1ccccc1>>C[Si](C)(C)CCOCn1nc(-c2ccc(C=Cc3ccccc3)cc2)c2c1-c1ccsc1C2,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20080051416A1,Cc1c(F)cc(C(=O)OC(C)(C)C)cc1-c1ccc(C(=O)NCC(C)(C)C)cc1C(=O)O.Nc1nccs1>>Cc1c(F)cc(C(=O)OC(C)(C)C)cc1-c1ccc(C(=O)NCC(C)(C)C)cc1C(=O)Nc1nccs1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20060004078A1,CN(C)CC(C)(C)C=Cc1ccccc1>>CN(C)CC(C)(C)CCc1ccccc1,[Pd],CO,,,,test
US20120214766A1,CC(C)(NC(=O)c1nn(-c2cc(Br)ccn2)c2c1C[C@H]1C[C@@H]21)C(F)(F)F.N#C[Zn]C#N>>CC(C)(NC(=O)c1nn(-c2cc(C#N)ccn2)c2c1C[C@H]1C[C@@H]21)C(F)(F)F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(=O)N(C)C,,,,test
US20050277772A1,C[C@@H](Oc1nnc(-c2c(O)ccc3ccccc23)c2ccccc12)c1ccccc1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>C[C@@H](Oc1nnc(-c2c(OS(=O)(=O)C(F)(F)F)ccc3ccccc23)c2ccccc12)c1ccccc1,,ClCCl,,c1ccncc1,,test
US20100152160A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)CC1CNc2cc(Cl)ccc2O1>>COC(=O)CC1CN(C(=O)OC(C)(C)C)c2cc(Cl)ccc2O1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20120232056A1,CC(C)(C)OC(=O)n1ncc2cc(B3OC(C)(C)C(C)(C)O3)ccc21.COC(=O)c1ccc2nc(OS(=O)(=O)C(F)(F)F)c(N3CCN(c4ccccn4)C[C@@H]3C)nc2c1>>COC(=O)c1ccc2nc(-c3ccc4c(cnn4C(=O)OC(C)(C)C)c3)c(N3CCN(c4ccccn4)C[C@@H]3C)nc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20130022587A1,COC(=O)C(CCCNC(=O)OC(C)(C)C)C(=O)OC>>COC(=O)C(CCCNC(=O)OC(C)(C)C)C(=O)O,,CO,O,[Li+].[OH-],,test
US20150087639A1,CCCCN(CCCC)c1ccc([N+](=O)[O-])cc1F>>CCCCN(CCCC)c1ccc(N)cc1F,[Pd],CO,,ClCCl,,test
US20160264567A1,CC(C)(C)OC(=O)N(Cc1cc(-c2cnc(C(F)(F)F)nc2)ncc1OC(F)(F)F)C(=O)OC(C)(C)C.Cl>>Cl.NCc1cc(-c2cnc(C(F)(F)F)nc2)ncc1OC(F)(F)F,,C1COCCO1,,,,test
US05516774,Cc1ccc(F)cc1C(=O)Nc1ccc(C(=O)Cl)c(Cl)c1.c1ccc2c(c1)Cn1cccc1CN2>>Cc1c(F)cccc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)c(Cl)c1,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20160039811A1,CCOC(=O)C(C(C)C)n1cc(Br)c2[nH]nc(N)c2c1=O>>CC(C)C(C(=O)O)n1cc(Br)c2[nH]nc(N)c2c1=O,,O,,CCO,[Na+].[OH-],test
US20040053956A1,O=C(Cl)OCC(Cl)(Cl)Cl.c1ccc2c(c1)CCNC2>>O=C(OCC(Cl)(Cl)Cl)N1CCc2ccccc2C1,,ClCCl,,CCN(CC)CC,,test
US20060089346A1,CI.C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@@H]1C(=O)Nc2ccccc2S[C@@H]1c1cc(F)cc(F)c1>>C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@@H]1C(=O)N(C)c2ccccc2S[C@@H]1c1cc(F)cc(F)c1,,CN(C)C=O,,[H-].[Na+],,test
US20030181519A1,CI.COc1ccc(-c2ccc3c(Br)c(OC)ccc3c2)cc1>>COc1ccc(-c2ccc3c(C)c(OC)ccc3c2)cc1,,C1CCOC1,O,CN(C)CCN(C)C,[Li]CCCC,test
US04665075,CCOC(=O)c1ccc(OCc2ccccc2)cc1[N+](=O)[O-]>>CCOC(=O)c1ccc(OCc2ccccc2)cc1N,[Ni],CCO,,[H][H],,test
US20160095858A1,Cc1ccccc1N(C)c1nc(C(C)(C)C)ccc1C(=O)NS(=O)(=O)c1cccc([N+](=O)[O-])c1>>Cc1ccccc1N(C)c1nc(C(C)(C)C)ccc1C(=O)NS(=O)(=O)c1cccc(N)c1,[Zn],CC(=O)O,,,,test
US06184249B2,CC1(C(=O)Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)CO1.N>>CC(O)(CN)C(=O)Nc1ccc([N+](=O)[O-])c(C(F)(F)F)c1,,CO,,,,test
US20150119380A1,CC(C)(C)OC(=O)NCCOc1ccc2cc(C(=O)CBr)c(=O)oc2c1.Cc1cnc(N)c(C)n1>>Cc1cn2cc(-c3cc4ccc(OCCNC(=O)OC(C)(C)C)cc4oc3=O)nc2c(C)n1,,CC#N,,,,test
US20060035841A1,CC(C)[Si](Cl)(C(C)C)C(C)C.Oc1cc(Br)ccc1Cl>>CC(C)[Si](Oc1cc(Br)ccc1Cl)(C(C)C)C(C)C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20060183785A1,CC(=O)c1cccc(-c2ccccc2OC(F)(F)F)c1.CCOC(=O)C(=O)OCC>>CCOC(=O)CC(=O)c1cccc(-c2ccccc2OC(F)(F)F)c1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20140371449A1,CC1(C)O[C@@H]2[C@@H](O)C[C@@H](NC(c3ccccc3)(c3ccccc3)c3ccccc3)[C@@H]2O1.Cc1ccc(S(=O)(=O)OCCOCc2ccccc2)cc1>>CC1(C)O[C@H]2[C@H](NC(c3ccccc3)(c3ccccc3)c3ccccc3)C[C@H](OCCOCc3ccccc3)[C@H]2O1,,CN(C)C=O,,[H-].[Na+],,test
US20150329523A1,COc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Oc2ccccc2)cc1.Nc1ccc(Oc2ccnc(Cl)n2)c2ccccc12>>COc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)cc1,,CC(=O)OC(C)C,,CCN(CC)CC,,test
US20080242685A1,Nc1c(Cl)nc(Br)nc1Cl.OB(O)c1ccccc1>>Nc1c(Cl)nc(-c2ccccc2)nc1Cl,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080085890A1,C1CN(CCN2CCOCC2)CCN1.COC=C1C(=O)NC(=O)c2ccc(Br)cc21>>O=C1NC(=O)c2ccc(Br)cc2/C1=C/N1CCN(CCN2CCOCC2)CC1,,CN(C)C=O,,,,test
US20130281438A1,COc1ccc(CN2C(=O)C3(CC3)c3c(Cl)nc(Cl)nc32)cc1>>COc1ccc(CN2CC3(CC3)c3c(Cl)nc(Cl)nc32)cc1,,C1CCOC1,,CO,,test
US06627651B1,CCCOCc1ccc(CO)cc1.COC(=O)C1=Cc2cc(O)ccc2S(=O)(=O)CC1>>CCCOCc1ccc(COc2ccc3c(c2)C=C(C(=O)OC)CCS3(=O)=O)cc1,,C1CCOC1,Cc1ccccc1,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05731432,CCOC(=O)N=NC(=O)OCC.OCCBr.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>COC(=O)c1cccc(OCCBr)c1,,C1CCOC1,,,,test
US20080161559A1,COC(=O)CS.N#Cc1cc(Br)ccc1F>>COC(=O)c1sc2ccc(Br)cc2c1N,,CN(C)C=O,,[Na+].[OH-],,test
US20040186118A1,CSc1ccc(C(=O)O)cc1[N+](=O)[O-].O=S([O-])OO>>CS(=O)(=O)c1ccc(C(=O)O)cc1[N+](=O)[O-],,O,,CO,,test
US04752610,CN(c1ccncc1[N+](=O)[O-])n1cccc1>>CN(c1ccncc1N)n1cccc1,[Pd],CO,,CC(C)O,,test
US20110092505A1,CC(C)(C)OC(=O)N1CCN(c2cc([N+](=O)[O-])cc(-c3ccnc(N(C(=O)OC(C)(C)C)C4CCCCC4)c3)n2)CC1>>CC(C)(C)OC(=O)N1CCN(c2cc(N)cc(-c3ccnc(N(C(=O)OC(C)(C)C)C4CCCCC4)c3)n2)CC1,[Pd],CCO,,O=C[O-].[NH4+],,test
US04303666,Nc1cc([Se]c2ccccc2)ccc1[N+](=O)[O-]>>Nc1ccc([Se]c2ccccc2)cc1N,,Cl,,,,test
US20130143863A1,COc1cncc(N2CCc3nc(OC)ccc3C2=O)c1>>COc1cncc(N2CCc3nc(O)ccc3C2=O)c1,,C1COCCO1,Cl,,,test
US04997847,NCCCCCCC(=O)O.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=C(O)CCCCCCNS(=O)(=O)c1ccc(Cl)cc1,,[Na+],[OH-],,,test
US20030130328A1,CN(C)c1ccc(C(=O)CC#N)cc1.NN>>CN(C)c1ccc(-c2cc(N)[nH]n2)cc1,,CCO,,,,test
US04318913,CSC(=NC#N)N(C)N=Cc1ccccc1.NCCCOc1cccc(CN2CCCCC2)c1>>Cn1nc(N)nc1NCCCOc1cccc(CN2CCCCC2)c1,,CC(C)=O,,Cl,,test
US20150246923A1,CC(C)NN.N#CC1CCCCC1=O>>CC(C)n1nc2c(c1N)CCCC2,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20130190268A1,O=C(O)CCCCNC(=O)NCCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21.O=C1CCC(=O)N1O>>O=C(NCCCCC(=O)ON1C(=O)CCC1=O)NCCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21,,CN(C)C=O,,CCN(CC)CC,CCOC(=O)Cl,test
US20140163002A1,CC(C)(C)OC(=O)CBr.Cc1ccc(F)c(C=O)c1F>>Cc1ccc(F)c(C(O)CC(=O)OC(C)(C)C)c1F,[Zn],C1CCOC1,C1CCOC1,C[Si](C)(C)Cl,,test
US20050215556A1,COc1ccc(OC)c(N)c1.O=C1OC(=O)c2ccccc21>>COc1ccc(OC)c(N2C(=O)c3ccccc3C2=O)c1,,CC(C)=O,,,,test
US05756545,CC(C)[C@H](N)C(=O)OC(C)(C)C.O=S(=O)(Cl)c1ccc(-c2ccc(Br)cc2)cc1>>CC(C)[C@H](NS(=O)(=O)c1ccc(-c2ccc(Br)cc2)cc1)C(=O)OC(C)(C)C,,ClCCl,,CN1CCOCC1,Cl,test
US20100168188A1,BrCc1ccccc1.O=C1CCc2c1ccc1[nH]ncc21>>O=C1CCc2c1ccc1nn(Cc3ccccc3)cc21,,CN(C)C=O,,,,test
US20130116263A1,COC(=O)/C=C/c1cnc(SC)nc1NC1CCCC1>>CSc1ncc2ccc(=O)n(C3CCCC3)c2n1,,CN1CCCC1=O,,C1CCC2=NCCCN2CC1,O,test
US20070032519A1,CC(C)c1ccc(Cc2cn([Si](C(C)C)(C(C)C)C(C)C)c3ncccc23)cn1>>CC(C)c1ccc(Cc2c[nH]c3ncccc23)cn1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20150210698A1,CC(C)(C)OC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.CN1CCN([C@@H]2CC[C@@H](n3cc(I)c4c(N)ncnc43)CC2)CC1>>CN1CCN([C@@H]2CC[C@@H](n3cc(-c4ccc(NC(=O)OC(C)(C)C)cc4)c4c(N)ncnc43)CC2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,ClCCl,O=C([O-])[O-].[Na+].[Na+],test
US20090318408A1,CCOC(=O)C(F)(F)CN(CCCc1ccccc1)c1nc(Cl)ncc1[N+](=O)[O-]>>O=C1Nc2cnc(Cl)nc2N(CCCc2ccccc2)CC1(F)F,[Fe],CC(=O)O,,,,test
US04657855,CC(C)=O.Cc1ccc(S(=O)(=O)N[C@@H](C)C(=O)Oc2c[nH]c(-c3ccc(Cl)cc3)c2)cc1.c1ccc(-c2ccc[nH]2)cc1>>CCCCCCCCCCCCO,,CC(C)=O,,,,test
US20100286181A1,CO/N=C1\CN(c2nc(-c3ncnn3C)c(C(=O)OC)s2)CCC1NC(=O)c1[nH]c(C)c(Cl)c1Cl>>CO/N=C1\CN(c2nc(-c3ncnn3C)c(C(=O)O)s2)CCC1NC(=O)c1[nH]c(C)c(Cl)c1Cl,,C1CCOC1,,[I-].[Li+],,test
US04012499,CCOC(=O)CCBr.O=C1c2ccccc2S(=O)(=O)c2cc(-c3nnn[nH]3)ccc21>>O=C(O)CCn1nnnc1-c1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O,,CC(C)=O,O,[Na+].[OH-],,test
US20090324581A1,CC(C)(C)OC(=O)CCN(CC(=O)N1CCc2cc(CCc3cc(-c4ccccc4)c(C(F)(F)F)s3)ccc21)C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C(O)CCNCC(=O)N1CCc2cc(CCc3cc(-c4ccccc4)c(C(F)(F)F)s3)ccc21,,ClCCl,,,,test
US20140171446A1,Cc1ccncc1C(=O)Nc1cnc(-c2cc(OC3CC3)ccc2Cl)cn1.Cl>>Cc1ccncc1C(=O)Nc1cnc(-c2cc(OC3CC3)ccc2Cl)cn1.Cl,,CCOC(C)=O,CCOCC,,,test
US20080009530A1,CC(C)Oc1cc(CCC(=O)O)n(Cc2ccc(Cl)cc2Cl)n1.CCCCCCS(N)(=O)=O>>CCCCCCS(=O)(=O)NC(=O)CCc1cc(OC(C)C)nn1Cc1ccc(Cl)cc1Cl,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20050261299A1,N#Cc1ccc(CCC2OCCO2)cc1.OO>>NC(=O)c1ccc(CCC2OCCO2)cc1,,CO,,Cl,[Na+].[OH-],test
US20140234254A1,NO.O=Cc1cnn2ccc(Br)cc12>>O/N=C/c1cnn2ccc(Br)cc12,,CCO,O,Cl,,test
US20030207877A1,BrBr.CC(=O)c1cc(C)oc1C>>Cc1cc(C(=O)CBr)c(C)o1,,C1COCCO1,CCOCC,[Cl-].[NH4+],,test
US05532235,CN(C)C=C1CCN(C(=O)c2ccc([N+](=O)[O-])cc2)c2ncccc2C1=O.NN>>O=C(c1ccc([N+](=O)[O-])cc1)N1CCc2cn[nH]c2-c2cccnc21,,CO,,O,,test
US20150232481A1,C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(CO)nn23)CC1.CS(=O)(=O)Cl>>C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(COS(C)(=O)=O)nn23)CC1,CN(C)c1ccncc1,ClCCl,,,,test
US20160068515A1,C[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1ncc(B2OC(C)(C)C(C)(C)O2)cn1.Cn1ncn(-c2ccc(Br)cc2F)c1=O>>C[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1ncc(-c2ccc(-n3cnn(C)c3=O)c(F)c2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US04039577,C=C(C)c1ccccc1.Cc1ccc(NC(N)=O)cc1>>Cc1ccc(NC(=O)NC(C)(C)c2ccccc2)cc1,,CC#N,,Cl,,test
US20110294788A1,BrCc1ccccc1.CCOC(=O)CC(=O)CC(=O)OCC>>CCOC(=O)CC(=O)C(Cc1ccccc1)C(=O)OCC,,CCO,,[Na],,test
US20110046127A1,COc1ccc(CN)cc1.O=C(Nc1ccccc1)c1cnc2cc(C3CCCC3)c(Cl)nn12>>COc1ccc(CNc2nn3c(C(=O)Nc4ccccc4)cnc3cc2C2CCCC2)cc1,,ClCCl,,,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n([C@@H]2CC[C@@H](O[C@@H]3CCC[C@@H]3O)CC2)c2ncnn12>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n([C@@H]2CC[C@@H](OC3CCCC3=O)CC2)c2ncnn12,,CC#N,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20140294805A1,CC(=O)NCc1ccc(S(=O)(=O)Cc2ccccc2)cc1.Cl>>Cl.NCc1ccc(S(=O)(=O)Cc2ccccc2)cc1,,CC(C)O,,,,test
US05733905,Cc1ccccc1C(=O)Cl.Nc1ccc(C(=O)N2CCc3cccn3-c3ccccc32)cc1>>Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCc3cccn3-c3ccccc32)cc1,,ClCCl,,CCN(CC)CC,,test
US04245088,C=C1CC(=O)O1.O=C(Cc1cccs1)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(CO)CS[C@H]12.[Na+]>>CC(=O)CC(=O)OCC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)Cc3cccs3)[C@H]2SC1.[Na+],,CN(C)C=O,,CCN(CC)CC,Cl,test
US20070259910A1,CC(=O)O.O=[N+]([O-])c1cc(C(F)(F)F)ccc1CCl>>CC(=O)OCc1ccc(C(F)(F)F)cc1[N+](=O)[O-],,CC(=O)O,O,CC(=O)[O-].[Na+],,test
US20140323474A1,CO/C=C/[C@H]1C[C@H]2CSC(NC(=O)c3ccccc3)=N[C@@]2(c2cc(Br)ccc2F)CO1.COC(OC)OC>>COC(OC)C(C(OC)OC)[C@H]1C[C@H]2CSC(NC(=O)c3ccccc3)=N[C@@]2(c2cc(Br)ccc2F)CO1,,ClCCl,,O=C([O-])O.[Na+],,test
US20020032189A1,CCN(CC)CCC1CCc2cc(O)ccc2C1.Cl.ClCc1ccc(-c2ccccc2)cc1>>CCN(CC)CCC1CCc2cc(OCc3ccc(-c4ccccc4)cc3)ccc2C1.Cl,,CN(C)C=O,O,[H-].[Na+],,test
US20040116428A1,CS(=O)(=O)Cl.OCCCOc1ccc(OC(F)(F)F)cc1Cl>>CS(=O)(=O)OCCCOc1ccc(OC(F)(F)F)cc1Cl,,ClCCl,,CCN(CC)CC,,test
US20110212053A1,C=CCBr.CC(C)(C#N)c1ccc(-c2n[nH]c3cnc4ccc(Br)cc4c23)cc1>>C=CCn1nc(-c2ccc(C(C)(C)C#N)cc2)c2c3cc(Br)ccc3ncc21,,CCO,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],,test
US20040122050A1,CCOC(=O)CSCC1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1>>O=C(O)CSCC1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1,,CO,O,Cl,[Li+].[OH-],test
US20140288081A1,CS(=O)(=O)N=S=O.Cc1ccccc1N>>c1ccc2sncc2c1,,Cc1ccccc1,,O=S(Cl)Cl,c1ccncc1,test
US20060183762A1,CC1COc2c(F)c(F)cc3c2N1C(=O)C3=O.[OH-]>>CC1COc2c(F)c(F)cc(C(=O)O)c2N1,,[Na+],[OH-],OO,,test
US20010011086A1,CC(=O)Cl.O=Cc1ccc2c(c1)C(=O)c1cccc(O)c1-2>>CC(=O)Oc1cccc2c1-c1ccc(C=O)cc1C2=O,,C1CCOC1,,CCN(CC)CC,,test
US20060223996A1,CN(CCOc1cc(N=[N+]=[N-])nc(N2CCOCC2)n1)C(=O)OC(C)(C)C>>CN(CCOc1cc(N)nc(N2CCOCC2)n1)C(=O)OC(C)(C)C,[Pd],C1CCOC1,CO,,,test
US05204462,CCCCCC(=O)N1CCC[C@H]1C(=O)OCc1ccccc1>>CCCCCC(=O)N1CCC[C@H]1C(=O)O,[Pd],CO,,O,,test
US20050245602A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1ccc(C2=C(c3ccccc3)CCCc3ccccc32)cc1>>O=S(=O)(Oc1ccc(C2=C(c3ccccc3)CCCc3ccccc32)cc1)C(F)(F)F,,ClCCl,O,c1ccncc1,,test
US20080146569A1,CC(C)(C)OC(=O)c1ccc(N2CCC(NC(=O)c3ccc(-c4cccc(F)c4)nc3)CC2)nc1>>O=C(O)c1ccc(N2CCC(NC(=O)c3ccc(-c4cccc(F)c4)nc3)CC2)nc1,,Cc1ccccc1,,ClCCl,O=C(O)C(F)(F)F,test
US20110046130A1,N#Cc1cc2c(nc1I)CCN1C(=O)CCCC21.OC1CCN(C2CCC2)CC1>>N#Cc1cc2c(nc1OC1CCN(C3CCC3)CC1)CCN1C(=O)CCCC21,[Cu]I,Cc1ccccc1,,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US20120220552A1,CCCCCCCCOc1ccc(C2CN(C(=O)CC(=O)OCC)CCO2)cc1>>CCCCCCCCOc1ccc(C2CN(C(=O)CC(=O)O)CCO2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20080312232A1,ClC1(Cl)C=CN=CN1.O=[N+]([O-])c1ccc(O)c(F)c1>>O=[N+]([O-])c1ccc(Oc2cc(Cl)ncn2)c(F)c1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20150133674A1,CC(C)(C)O.CCOC(=O)CN.O=C=NS(=O)(=O)Cl>>CCOC(=O)CNS(=O)(=O)NC(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,Cl,test
US05037986,CC(=O)OCC(C)(C)n1cnc2c(O)nc3ccccc3c21>>Oc1nc2ccccc2c2[nH]cnc12,,Cl,,,,test
US04935437,CC(C)(C#N)c1cc(C(O)c2cccnc2)cc(C(C)(C)C#N)c1>>CC(C)(C#N)c1cc(Cc2cccnc2)cc(C(C)(C)C#N)c1,,ClCCl,O=S(Cl)Cl,,,test
US20070032485A1,CC[C@@H]1C[C@H](Nc2ncc(N(C)C)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)c2nc(OC)ccc2N1C(=O)OCC(C)(C)C(=O)OC>>CC[C@@H]1C[C@H](Nc2ncc(N(C)C)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)c2nc(OC)ccc2N1C(=O)OCC(C)(C)C(=O)O,,CCO,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[Na+].[OH-],test
US20040209892A1,COc1cc2nccc(Oc3ccc([N+](=O)[O-])c([N+](=O)[O-])c3)c2cc1OC>>COc1cc2nccc(Oc3ccc(N)c(N)c3)c2cc1OC,[Zn],C1CCOC1,,CC(=O)O,,test
US20030008890A1,COc1ccc2c(c1)CC1CNCC2C1.Cl>>Cl.Oc1ccc2c(c1)CC1CNCC2C1,,Br,,[NH4+].[OH-],,test
US20090149483A1,C[Mg]Br.Cn1c(=O)c2c(c(C=O)c(N3CCC[C@@H](NC(=O)OC(C)(C)C)C3)n2Cc2ccccc2Cl)n(C)c1=O>>CC(O)c1c(N2CCC[C@@H](NC(=O)OC(C)(C)C)C2)n(Cc2ccccc2Cl)c2c(=O)n(C)c(=O)n(C)c12,,C1CCOC1,,[Cl-].[NH4+],,test
US20060111347A1,O=C1CC(CSc2ccc3ccccc3c2)CO1.O=S([O-])OO>>O=C1CC(CS(=O)(=O)c2ccc3ccccc3c2)CO1,,C1COCCO1,,O,,test
US20020004501A1,C=CCCCN1CCCCCCC1=O.O=[Os](=O)(=O)=O>>O=CCCCN1CCCCCCC1=O,O=[Os](=O)(=O)=O,C1CCOC1,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US06242439B1,CC(C)(C)[Si](C)(C)N1C(=O)C[C@@H]1Cc1ccccc1.CI>>C[C@@H]1C(=O)N([Si](C)(C)C(C)(C)C)[C@H]1Cc1ccccc1,,C1CCOC1,CCOC(C)=O,CC(C)NC(C)C,[Li]CCCC,test
US20130096121A1,CC1(C)CCCC(=O)C1.Cc1c(N)cccc1Br>>Cc1c(Br)cccc1NC1CCCC(C)(C)C1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150336962A1,COC(=O)[C@H](CCn1cc(NC(=O)c2cnn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1)NC(=O)OC(C)(C)C>>COC(=O)[C@@H](N)CCn1cc(NC(=O)c2cnn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20040127527A1,CCOC(=O)Cc1nc(-c2ccc(Cl)cc2)sc1-c1ccccc1.N>>NC(=O)Cc1nc(-c2ccc(Cl)cc2)sc1-c1ccccc1,,CO,,,,test
US20150315198A1,CC(=O)n1c(C#N)c(C)c2cc(Cl)ccc21.O=C1CCC(=O)N1Br>>CC(=O)n1c(C#N)c(CBr)c2cc(Cl)ccc21,,ClC(Cl)(Cl)Cl,,,,test
US04824465,C#CCBr.CC(C)(C)c1nn(-c2cc3[nH]c(=O)sc3cc2Cl)c(=O)o1>>C=CCn1c(=O)sc2cc(Cl)c(-n3nc(C(C)(C)C)oc3=O)cc21,,CN(C)C=O,,O,[H-].[Na+],test
US20140179680A1,CCC1CCC(C(=O)OC)C1>>CCC1CCC(CO)C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120184562A1,CC(C)(C)OC(=O)Nc1nc(Cl)ccc1C=O.CO>>COc1ccc(C=O)c(NC(=O)OC(C)(C)C)n1,,CO,,C[O-].[Na+],,test
US20110306636A1,CC(C)(C)OC(=O)CCN.N#Cc1ccnc(Cl)c1>>CC(C)(C)OC(=O)CCNc1cc(C#N)ccn1,,CCOCC,CS(C)=O,CCN(C(C)C)C(C)C,Cl,test
US05571833,BrCc1ccccc1.Cc1c([N+](=O)[O-])ccc(O)c1Cl>>Cc1c([N+](=O)[O-])ccc(OCc2ccccc2)c1Cl,,CN(C)C=O,,O,[H-].[Na+],test
US20130281434A1,Cc1cc2nc(-c3cnc4cnn(C)c4c3)sc2c(-c2ccc(Cl)cc2)c1[C@@H](COC(=O)C(C)(C)C)OC(C)(C)C>>Cc1cc2nc(-c3cnc4cnn(C)c4c3)sc2c(-c2ccc(Cl)cc2)c1[C@@H](CO)OC(C)(C)C,,C1CCOC1,CO,[Na+].[OH-],,test
US20140275027A1,COc1ccc(F)cc1-c1c(F)cnc2c1cc(C1=CCN(C(=O)OC(C)(C)C)CC1)n2S(=O)(=O)c1ccccc1>>COc1ccc(F)cc1-c1c(F)cnc2[nH]c(C3=CCNCC3)cc12,,C1COCCO1,ClCCl,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20050250825A1,CCOC(=O)C(C)(C)Oc1ccc(OCCc2nc(-c3cccc(Oc4ccccc4C)c3)oc2C)cc1>>CCOC(=O)C(C)(C)Oc1ccc(OCCc2nc(-c3cccc(Oc4ccccc4)c3)oc2C)cc1,,CCOC(C)=O,,,,test
US20070105943A1,C1CCOC1.CO.N#Cc1ccccc1.O>>NCc1ccc(OCc2ccco2)cc1,,O,,[Al+3].[H-].[H-].[H-].[H-].[Li+],[Cl-].[NH4+],test
US20030100554A1,CCc1n[nH]c(CCO)c1Oc1cc(F)cc(C#N)c1.N#Cc1ccc(O)cc1>>CCc1n[nH]c(CCOc2ccc(C#N)cc2)c1Oc1cc(F)cc(C#N)c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120135990A1,CC(C)(C)OC(=O)N1CC(O)C2C1CCN2C(=O)OCc1ccccc1.O=C(O)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N1CC(OC(=O)c2ccc([N+](=O)[O-])cc2)C2C1CCN2C(=O)OCc1ccccc1,,c1ccccc1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04880808,CC1CN(Cc2ccccc2)CCN1C(=O)OC(C)(C)C>>CC1CNCCN1C(=O)OC(C)(C)C,[Pd],CO,,[H][H],,test
US05534481,Cn1nc(S(=O)(=O)NC(C)(C)C)c2c(F)cccc21>>Cn1nc(S(N)(=O)=O)c2c(F)cccc21,,O=C(O)C(F)(F)F,,,,test
US20040142979A1,CC(C)(C)OC(=O)C1(S(=O)(=O)c2ccc(Br)nc2)CCOCC1.CCCCCc1ccc(B(O)O)cc1>>CCCCCc1ccc(-c2ccc(S(=O)(=O)C3(C(=O)OC(C)(C)C)CCOCC3)cn2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20090280083A1,CCOC(=O)c1c(C(C)C)nn(C2CC2)c1C1=Cc2cc(OC)ccc2-c2c(C3CCCCC3)c3ccc(C(=O)OC(C)(C)C)cc3n2C1>>CCOC(=O)c1c(C(C)C)nn(C2CC2)c1C1=Cc2cc(OC)ccc2-c2c(C3CCCCC3)c3ccc(C(=O)O)cc3n2C1,,CC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US03962263,Nc1cc(Cl)cnc1N.O=C(Cl)C(F)(F)F>>Nc1ncc(Cl)c(C(=O)C(F)(F)F)c1N,,C1CCOC1,,CCN(CC)CC,,test
US05530119,C1CCOC1.CC(C)(C)OC(=O)N1CCNCC1.CCN(CC)CC.CCOCC.O>>CC(C)(C)OC(=O)N1CCN(C(=O)N2CCOCC2)CC1,,CCOCC,,,,test
US20100216814A1,CC(=CBr)c1ccncc1.CN1CCc2[nH]c3ccc(C(F)(F)F)cc3c2C1>>C/C(=C\n1c2c(c3cc(C(F)(F)F)ccc31)CN(C)CC2)c1ccncc1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20120028800A1,CC(C)(C)C(=O)Cl.Cc1cc(OCc2ccccc2)cc(C)c1C1C(=O)C2C3C=CC(O3)C2C1=O>>Cc1cc(OCc2ccccc2)cc(C)c1C1=C(OC(=O)C(C)(C)C)C2C3C=CC(O3)C2C1=O,,ClCCl,,CCN(CC)CC,,test
US20090042929A1,NC(=NO)c1ccc(Cl)cc1.O=C(Cl)C12CC3CC(CC(C3)C1)C2>>Clc1ccc(-c2noc(C34CC5CC(CC(C5)C3)C4)n2)cc1,,Cc1ccccc1,,c1ccncc1,,test
US20040127538A1,COC(OC)c1ccc(F)c(C=O)c1.c1ccc2scnc2c1>>COC(OC)c1ccc(F)c(C(O)c2nc3ccccc3s2)c1,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US20160039783A1,CCOC(=O)C(OC(C)(C)C)c1c(-c2ccc3c(c2)CCCO3)csc1C.O=C1CCC(=O)N1Br>>CCOC(=O)C(OC(C)(C)C)c1c(C)sc(Br)c1-c1ccc2c(c1)CCCO2,,CCOC(C)=O,CN(C)C=O,O,,test
US20100016279A1,C[C@@H](N)c1ccc(Br)cc1.Cc1ccc(S(=O)(=O)N(CCCl)CCCl)cc1>>Cc1ccc(S(=O)(=O)N2CCN([C@H](C)c3ccc(Br)cc3)CC2)cc1,,CCN(C(C)C)C(C)C,,CCO,O,test
US20140031355A1,CO.O=C(O)c1ccc2cccnc2c1O>>COC(=O)c1ccc2cccnc2c1O,,O,,O=S(=O)(O)O,,test
US20110245229A1,CCOC(=O)c1cnc(SC)nc1Cl.Cn1ccc(N)n1>>CCOC(=O)c1cnc(SC)nc1Nc1ccn(C)n1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20160031830A1,CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1CBr.NC1CCOCC1>>CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)[C@H]1c1ccc(C#N)cc1CNC1CCOCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100113462A1,CCOC(=O)C1(N)Cc2ccccc2C1.O=C(O)c1cc(F)cc2c1OCOC2>>CCOC(=O)C1(NC(=O)c2cc(F)cc3c2OCOC3)Cc2ccccc2C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04552876,O=C(CCc1ccc(O)c([N+](=O)[O-])c1)CCc1ccc(O)c([N+](=O)[O-])c1>>Nc1cc(CCC(=O)CCc2ccc(O)c(N)c2)ccc1O,[Pd],CCOC(C)=O,CO,,,test
US20060040919A1,CC(=O)N1CCc2ccccc2C1[N+](=O)[O-].Cl>>CC(=O)N1CCc2ccccc2C1N.Cl,[Pd],CO,,,,test
US07556908B2,C=C(C)C(=O)OCC(=O)O.OC1C2CC3CC(C2)CC1(O)C3>>C=C(C)C(=O)OCC(=O)OC12CC3CC(CC(O)(C3)C1)C2,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20140163000A1,CNC.O=C(O)C1CCC(Oc2ccncc2[N+](=O)[O-])CC1>>CN(C)C(=O)C1CCC(Oc2ccncc2[N+](=O)[O-])CC1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20040014962A1,CS(=O)(=O)Cl.NC(=O)c1coc(N2CC(O)C2)n1>>CS(=O)(=O)OC1CN(c2nc(C(N)=O)co2)C1,,ClCCl,c1ccncc1,CCN(CC)CC,CO,test
US20130079321A1,CC(C)(C)OC(=O)N1CCC2(CCNCC2)C1.Cn1ncc([N+](=O)[O-])c1Cl>>Cn1ncc([N+](=O)[O-])c1N1CCC2(CCN(C(=O)OC(C)(C)C)C2)CC1,,CCO,,CCN(C(C)C)C(C)C,,test
US20110212937A1,CC(C)N.Clc1nc(Cl)c2c(n1)C(c1ccccc1)CC2>>CC(C)Nc1nc(Cl)nc2c1CCC2c1ccccc1,,CN1CCCC1=O,,O,,test
US05151431,COc1ccc(NCCC(=O)O)c([N+](=O)[O-])c1>>COc1cc2c(c([N+](=O)[O-])c1)NCCC2=O,,Cc1ccccc1,,O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3,,test
US20110015157A1,COC(=O)Cl.C[C@@H](c1ccc(-c2ccc(F)cc2F)cc1)N1CC[C@](CCN)(c2ccc(F)cc2)OC1=O>>COC(=O)NCC[C@]1(c2ccc(F)cc2)CCN([C@@H](C)c2ccc(-c3ccc(F)cc3F)cc2)C(=O)O1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US05420115,Clc1ncnc2nc[nH]c12.NC1CC1>>c1nc(NC2CC2)c2nc[nH]c2n1,,CO,,,,test
US04224341,COC(=O)C1Cc2ccccc2C1.O=C(Cl)c1ccccc1>>COC(=O)C1Cc2ccc(C(=O)c3ccccc3)cc2C1,,ClCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US05840732,O=c1cc2n(c(=O)n1CCCCCl)CCCS2(=O)=O.Sc1cccc2nccn12>>O=c1cc2n(c(=O)n1CCCCSc1cccc3nccn13)CCCS2(=O)=O,,CN(C)C=O,O,[H-].[Na+],,test
US20120288555A1,CCCCCCCCCCC=CC1CC(=O)OC1=O.O=C1C(=Cc2ccccc2F)CNCC1=Cc1ccccc1F>>CCCCCCCCCCC=CC(CC(=O)O)C(=O)N1CC(=Cc2ccccc2F)C(=O)C(=Cc2ccccc2F)C1,,ClCCl,,CCN(CC)CC,,test
US03947473,CC(=O)Oc1c(C)c(C)c2c(c1C)CCC(C)(C(=O)O)O2.[Cl-]>>CC(=O)Oc1c(C)c(C)c2c(c1C)CCC(C)(C(=O)Cl)O2,,Clc1ccccc1,,,,test
US20120309701A1,CC(=O)OC[C@H]1O[C@H](Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[C@@H](CC(=O)[O-])[C@H](OC(C)=O)[C@H]1OC(C)=O.COC(=O)c1cncc(Br)c1>>COC(=O)c1cncc(-c2ccc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)cc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080167371A1,O=Cc1ccc(O)c(Cl)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=Cc1ccc(OS(=O)(=O)C(F)(F)F)c(Cl)c1,,ClCCl,,c1ccncc1,,test
US20140213586A1,COc1cccc(N)c1.O=C(c1c[nH]c2ccccc12)C(Br)c1ccccc1>>COc1cccc(NC(C(=O)c2c[nH]c3ccccc23)c2ccccc2)c1,,CC#N,,,,test
US20080255113A1,C1CC2(CCO1)CO2.O=C(NCC1CCNCC1)OCc1ccccc1>>O=C(NCC1CCN(CC2(O)CCOCC2)CC1)OCc1ccccc1,,CO,,,,test
US20130245254A1,C1=COCCC1.Cc1cc(Br)cc2[nH]cnc12>>Cc1cc(Br)cc2c1ncn2C1CCCCO1,,C1CCOC1,CCOC(C)=O,CS(=O)(=O)O,,test
US20050148659A1,CC1(C)Oc2ccc(CC(=O)NC3CCCc4ccccc43)cc2C(N)C1O.CCc1ccc(S(=O)(=O)Cl)cc1>>CCc1ccc(S(=O)(=O)NC2c3cc(CC(=O)NC4CCCc5ccccc54)ccc3OC(C)(C)C2O)cc1,,ClCCl,O,CCN(CC)CC,CN(C)C=O,test
US05990105,C1CNCCN1.Nc1ccc(S(=O)(=O)c2cc(Br)nc(Br)c2)cc1>>Nc1ccc(S(=O)(=O)c2cc(Br)nc(N3CCNCC3)c2)cc1,,C1COCCO1,,CCN(CC)CC,,test
US20150284395A1,CCOC(=O)CC(=O)c1ccc2[nH]nnc2c1.CCc1cnc(-c2cn[nH]c2N)o1>>CCc1cnc(-c2cnn3c(=O)cc(-c4ccc5[nH]nnc5c4)[nH]c23)o1,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20140288063A1,COc1ccc(COc2nc(SC)ncc2C(=O)O)cc1Cl.NCc1ncccn1>>COc1ccc(COc2nc(SC)ncc2C(=O)NCc2ncccn2)cc1Cl,,C1CCOC1,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050234109A1,CC(C)(C)[Si](C)(C)OCCCCCC(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1>>O=S(=O)(c1ccc(Cl)cc1)C(CCCCCO)c1cc(F)ccc1F,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100252433A1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.CN(C)C(=O)/C=C/c1c[nH]c(C=O)c1>>CCOC(=O)/C=C/c1cc(/C=C/C(=O)N(C)C)c[nH]1,,c1ccccc1,,,,test
US20070244088A1,C1CNCCN1.CCOC(=O)c1cnc(Cl)c(Cl)c1>>CCOC(=O)c1cnc(N2CCNCC2)c(Cl)c1,,CCO,,CCN(CC)CC,,test
US05141948,CCCCCCCCOc1ccc(C(O)CN)cc1.O=C(Cl)c1c(F)cccc1Cl.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CCCCCCCCOc1ccc(C2CN=C(c3c(F)cccc3Cl)S2)cc1,,C1CCOC1,c1ccccc1,CCN(CC)CC,[Na+].[OH-],test
US06331563B1,CCOC(=O)C1(S(=O)(=O)c2ccccc2OC)CCN(CC)CC1>>CCN1CCC(C(=O)O)(S(=O)(=O)c2ccc(OC)cc2)CC1,,[Na+],[OH-],CO,,test
US20120065195A1,O=C1/C(=C/c2cccnc2)CCc2ccc(Br)cc21>>O=C1c2cc(Br)ccc2CCC1Cc1cccnc1,[Pt],CCO,,,,test
US20120309752A1,Cc1cc(C(F)(F)F)nn1CC(=O)O.Fc1cccc(F)c1C1CC(c2csc(C3CCNNC3)n2)=NO1>>Cc1cc(C(F)(F)F)nn1CC(=O)N1CCC(c2nc(C3=NOC(c4c(F)cccc4F)C3)cs2)CN1,,ClCCl,,,,test
US20040254156A1,CC(C)(C)OC(=O)NCc1ccccc1CC(=O)O.CN[C@H](CN1CCCC1)c1ccccc1>>CN(C(=O)Cc1ccccc1CNC(=O)OC(C)(C)C)[C@H](CN1CCCC1)c1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20100136142A1,CCOc1nccc2c1C(c1ccc(C#N)cc1OC)C(C(=O)n1ccnc1)=C(C)N2.N>>CCOc1nccc2c1C(c1ccc(C#N)cc1OC)C(C(N)=O)=C(C)N2,,CN(C)C=O,,,,test
US05296492,CC1(C)Oc2ccc(C#N)cc2[C@@H](n2cccc(CO[Si](C)(C)C(C)(C)C)c2=O)[C@@H]1O>>CC1(C)C=C(n2cccc(CO[Si](C)(C)C(C)(C)C)c2=O)c2cc(C#N)ccc2O1,,C1CCOC1,,O,[H-].[Na+],test
US20130059834A1,CCC[C@@H](NC(=O)OC(C)(C)C)C(=O)N1CC(F)C1.O=C(O)C(F)(F)F>>CCC[C@@H](N)C(=O)N1CC(F)C1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20090264469A1,CCCCCCCCC(=O)c1ccc(Br)cc1>>CCCCCCCCCc1ccc(Br)cc1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US05518732,O=C1O[C@H]([C@@H](O)CO)C(O)=C1O.[Na]>>O=C1O[C@H]([C@@H](O)CO)C(O)=C1O.[Na],,O,,,,test
US20100093748A1,CC(C)(C)OC(=O)N1CCC(C#N)CC1.CN(C)S(=O)(=O)n1c(Cl)nc2ccccc21>>CN(C)S(=O)(=O)n1c(C2(C#N)CCN(C(=O)OC(C)(C)C)CC2)nc2ccccc21,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US04487929,CC(C)(C)OC(=O)C1CCCN(C(=O)OCc2ccccc2)N1C(=O)C(CBr)CBr>>CC(C)(C)OC(=O)C1CCCN2CC(CBr)C(=O)N12,[Pd],CC(=O)O,CO,,,test
US20090275537A1,CN(C(=O)OCc1ccccc1)[C@H](CO)CCCN1C(=O)c2ccccc2C1=O>>CN[C@H](CO)CCCN1Cc2ccccc2C1,[Pd],CO,,[H][H],,test
US20140336412A1,CC(C)CC=C[N+](=O)[O-].Cc1noc(C)c1[N+](=O)[O-]>>Cc1noc(CC(CC(C)C)C[N+](=O)[O-])c1[N+](=O)[O-],,ClCCl,,,,test
US20140364413A1,CC(C)(C)OC(=O)c1ccc(-c2c(C=O)nc3c(N4CCOCC4)ccnn23)cn1.CCOP(=O)(Cc1ccc2ccccc2n1)OCC>>CC(C)(C)OC(=O)c1ccc(-c2c(/C=C/c3ccc4c(n3)CCCC4)nc3c(N4CCOCC4)ccnn23)cn1,,C1CCOC1,O,[Li]CCCC,[Cl-].[NH4+],test
US05569655,O=CO.[C-]#[N+]CC(=O)OC>>COC(=O)c1cocn1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20100204240A1,C#Cc1ncccc1OC(C)=O>>CCc1ncccc1OC(C)=O,O=[Pt]=O,CCO,,,,test
US05095014,CNC.O=C(Cl)N1CC(Oc2ccc(Cl)cc2Cl)C1>>CN(C)C(=O)N1CC(Oc2ccc(Cl)cc2Cl)C1,,C1CCOC1,O,,,test
US20040014763A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1C=C(CN)C=CC1(C)CN>>CC(C)(C)OC(=O)NCc1ccc(CN)cc1,,ClCCl,O,,,test
US04656167,COc1cccc2c1C[C@@H](N)[C@H](O)C2.O=C(Cl)CCl>>COc1cccc2c1C[C@@H](NC(=O)CCl)[C@H](O)C2,,ClCCl,,CCN(CC)CC,,test
US20090209524A1,CCCC[C@H](N)CCO.Cc1nc(N)nc(Cl)c1C#CCNC(=O)OC(C)(C)C>>CCCC[C@@H](CCO)Nc1nc(N)nc(C)c1C#CCNC(=O)OC(C)(C)C,,CCCCO,,,,test
US20060025433A1,N[C@@H]1CC[C@@H](CNc2nc(NCc3ccccc3OC(F)(F)F)ncc2[N+](=O)[O-])CC1.O=S(=O)(OCC(F)(F)F)C(Cl)(Cl)Cl>>O=[N+]([O-])c1cnc(NCc2ccccc2OC(F)(F)F)nc1NC[C@@H]1CC[C@@H](NCC(F)(F)F)CC1,,CC#N,,,,test
US20150111877A1,Cc1cccc(S(=O)(=O)N2CCCc3ncc(NC(=O)OC(C)(C)C)cc32)c1>>Cc1cccc(S(=O)(=O)N2CCCc3ncc(N)cc32)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150126490A1,CC(C)(C)[S@](=O)/N=C/c1cc(F)cc(Br)c1.C[N+](=O)[O-]>>CC(C)(C)[S@](=O)N[C@H](C[N+](=O)[O-])c1cc(F)cc(Br)c1,,C1CCOC1,,[Li]CCCC,,test
US20110160203A1,Cn1cc(C(=O)c2ccccc2)c2c(Cl)ncnc21.Nc1cccc(N)c1>>Cn1cc(C(=O)c2ccccc2)c2c(Nc3cccc(N)c3)ncnc21,,CCOCC,,O=C(O)C(F)(F)F,,test
US20160122331A1,N.O=C1CCOC(c2ccccc2)C1>>NC1CCOC(c2ccccc2)C1,[Pd],CO,,[H][H],,test
US20090318708A1,CCC(C)(Br)C(=O)OC.O=C1C[C@@H](C=C(F)F)CN1>>CCC(C(=O)OC)N1C[C@H](C=C(F)F)CC1=O,,C1CCOC1,O,[H-].[Na+],,test
US20120225061A1,CC(C)OB1OC(C)(C)C(C)(C)O1.CSc1cc(F)cc(F)c1>>CSc1cc(F)c(B2OC(C)(C)C(C)(C)O2)c(F)c1,,C1CCOC1,,[Li]CCCC,,test
US20160024009A1,N#Cc1cc(-c2ccc(OC(F)(F)F)cc2)nc(-c2ccc(OC(F)(F)F)cc2)c1>>NCc1cc(-c2ccc(OC(F)(F)F)cc2)nc(-c2ccc(OC(F)(F)F)cc2)c1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06093744,CC(C)c1cc(C(C)C)c(CC(=O)O)c(C(C)C)c1.CC(C)c1cc(O[Si](C)(C)C(C)(C)C)cc(C(C)C)c1OS(N)(=O)=O>>CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(C(C)C)cc(O[Si](C)(C)C(C)(C)C)cc2C(C)C)c(C(C)C)c1,CN(C)C=O,Cc1ccccc1,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US06803380B1,CN(C)C=NC(=O)c1ccc(S(C)(=O)=O)cc1.COc1ccc(NN)cc1>>COc1ccc(-n2ncnc2-c2ccc(S(C)(=O)=O)cc2)cc1,,CCO,,CCN(CC)CC,Cl,test
US20140206661A1,COc1cc(I)ccc1-c1nnc(N)s1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>COc1cc(-c2cnn(C)c2)ccc1-c1nnc(N)s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20040116509A1,COC(=O)c1sc(-c2ccccc2)cc1N(C(=O)[C@@H]1CC[C@@H](C)C[C@@H]1OC(C)=O)C(C)C>>CC(C)N(C(=O)[C@@H]1CC[C@@H](C)C[C@@H]1O)c1cc(-c2ccccc2)sc1C(=O)O,,C1COCCO1,O,[Li+].[OH-],,test
US06166006,COC(=O)C1=Cc2cc(-c3ccc(OC)cc3)ccc2SCC1>>COc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCS3)cc1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20070099955A1,COc1c(C)ccc2c1C[C@@H](C1CCNCC1)O[C@H]2CBr.FC(F)(F)c1ccc(CBr)cc1>>COc1c(C)ccc2c1C[C@@H](C1CCN(Cc3ccc(C(F)(F)F)cc3)CC1)O[C@H]2CBr,,CN1CCCC1=O,,,,test
US20150057238A1,BrBr.Nc1c(O)cccc1Cl>>Nc1c(O)cc(Br)cc1Cl,,ClCCl,,,,test
US05817654,O=C1Nc2ccc3ccccc3c2CCC1Cl.[N-]=[N+]=[N-]>>[N-]=[N+]=NC1CCc2c(ccc3ccccc23)NC1=O,,CS(C)=O,,O,,test
US20020013302A1,CC(C)(C)[Si](C)(C)Cl.C[C@@H](CO)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C>>C[C@H](CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)CO[Si](C)(C)C(C)(C)C,,O,,CN(C)C=O,c1c[nH]cn1,test
US20090105210A1,N#CC(C#N)=Cc1ccc(Cl)cc1Cl.Nc1nc[nH]n1>>N#Cc1c(-c2ccc(Cl)cc2Cl)nc2ncnn2c1N,,c1ccncc1,,,,test
US20050107248A1,C1CCOC1.CCCCCC.C[C@H](O)CC[C@H](C)O.Cc1c(P)c(P)c(C)n1-c1ccccc1>>Cc1c(P2C(C)CCC2C)c(P2[C@H](C)CC[C@H]2C)c(C)n1-c1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US20150315182A1,CS(=O)(=O)c1nc(Cl)c(F)c(Cl)n1.Cc1nc2ccc(F)cc2[nH]1>>Cc1nc2ccc(F)cc2n1-c1nc(Cl)c(F)c(Cl)n1,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20040019016A1,CN(C)S(=O)(=O)c1ccc(CO)cc1Br.O=S(Cl)Cl>>CN(C)S(=O)(=O)c1ccc(CCl)cc1Br,,CCCCCC,ClCCl,,,test
US20120088748A1,CC(C)(C)OC(=O)N1CCOC(CCN)C(c2ccc(Cl)c(Cl)c2)C1.COCC(=O)Cl>>COCC(=O)NCCC1OCCN(C(=O)OC(C)(C)C)CC1c1ccc(Cl)c(Cl)c1,,C1CCOC1,,CCN(CC)CC,O,test
US04497650,CNC(=O)N1C2=NC3(CCCC3)N(C)C(=O)N2c2ccccc21>>CN1C(=O)n2c(nc3ccccc32)NC12CCCC2,,C1CCOC1,,[Na+].[OH-],,test
US20030212094A1,BrCCCOC1CCCCO1.O=C1CCc2ccccc2N1>>O=C1CCc2ccccc2N1CCCO,,CN(C)C=O,O,[H-].[Na+],,test
US20030004340A1,CC1CN(Cc2ccccc2)CCC1(C)c1cccc(C#N)c1.C[Si](C)(C)C=[N+]=[N-]>>CC1CN(Cc2ccccc2)CCC1(C)c1cccc(-c2nn[nH]c2[Si](C)(C)C)c1,,C1CCOC1,,[Li]CCCC,,test
US20100222352A1,Brc1ccccn1.Nc1ccc(Cl)c(O)c1>>Oc1cc(Nc2ccccn2)ccc1Cl,,CCO,,,,test
US20040063975A1,Cc1c(O)ccc(OCC(=O)c2ccccc2)c1C>>Cc1c(O)cc2c(-c3ccccc3)coc2c1C,,Cc1ccccc1C,,O,,test
US20120202785A1,C[C@H](NC(=O)OC(C)(C)C)c1nc2ccccc2n1C1CCCOC1>>C[C@H](N)c1nc2ccccc2n1C1CCCOC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US03989749,C=[N+]=[N-].CCCCCC(O)CCCN(CCCCCCC(=O)O)C(N)=S>>CCCCCC(O)CCCN(CCCCCCC(=O)OC)C(N)=S,,CCOCC,,CC(=O)O,,test
US20020120137A1,Cc1ccc(C)c2c1NS(=O)(=O)c1ccccc1-2.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)N2c3c(C)ccc(C)c3-c3ccccc3S2(=O)=O)cc1,,c1ccncc1,,Cl,,test
US20120207679A1,CN1CCN(c2ccc(-c3nc4ccc(N)cc4s3)cn2)CC1.O=C(O)C(F)(F)F>>CN1CCN(c2ccc(-c3nc4ccc(NC(=O)C(F)(F)F)cc4s3)cn2)CC1,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,,test
US20050159469A1,CC(C)CC=O.CC[C@H](C)[C@@H](C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CNNC(=O)[C@@H](NC(=O)OC)C(C)(C)C)N1CCN(Cc2csc(COC)n2)C1=O>>CC[C@H](C)[C@@H](C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(CCC(C)C)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C)N1CCN(Cc2csc(COC)n2)C1=O,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04219510,CCOP1(=O)OCc2ccccc21>>O=P1(O)OCc2ccccc21,,O,,,,test
US20150238558A1,COC[C@H](c1ccccc1)N(Cc1ccc2c(ccn2C(=O)N[C@H]2C[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N(C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(C)(C)C)C2)c1)C(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(C)(C)C>>COC[C@H](c1ccccc1)N(Cc1ccc2c(ccn2C(=O)N[C@H]2C[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N(C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(C)(C)C)C2)c1)C(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)C(C)(C)C,,ClCCl,,C1CCNCC1,,test
US20100041698A1,COc1cccc(OC)c1CNCc1cc(Cl)ccc1[N+](=O)[O-].N#CBr>>COc1cccc(OC)c1CN1Cc2cc(Cl)ccc2N=C1N,,C1COCCO1,,,,test
US20060241302A1,COC(=O)CCc1cc(F)c(S(=O)(=O)c2ccc(Cl)cc2)nc1Cc1cc(F)ccc1F>>O=C(O)CCc1cc(F)c(S(=O)(=O)c2ccc(Cl)cc2)nc1Cc1cc(F)ccc1F,,CCO,,Cl,[Na+].[OH-],test
US20090042852A1,CCOC(=O)c1cc(C#N)c(N2CC3CN(C(=O)OC(C)(C)C)CC3C2)nc1C.O=C=NS(=O)(=O)c1ccccc1>>CCOC(=O)c1cc(C#N)c(N2CC3CN(C(=O)NS(=O)(=O)c4ccccc4)CC3C2)nc1C,,ClCCl,O=C(O)C(F)(F)F,CCN(CC)CC,,test
US20090221645A1,CC(Br)C(=O)c1nsc2ccccc12.S=C1NCCN1>>Br.CC1=C(c2nsc3ccccc23)N2CCN=C2S1,,CCO,,CC(=O)O,,test
US20090286811A1,Cc1cc(=O)n2ccsc2n1.O=Cc1ccc(Cl)cc1>>O=c1cc(/C=C/c2ccc(Cl)cc2)nc2sccn12,,CCO,,C,C[O-].[Na+],test
US20160060273A1,C1CSCCN1.COC(=O)c1ccc(-c2ccc(F)cc2)cc1F>>COC(=O)c1ccc(-c2ccc(F)cc2)cc1N1CCSCC1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20070049603A1,CCOC(=O)c1ccncc1O.OCc1ncccn1>>CCOC(=O)c1ccncc1OCc1ncccn1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140275528A1,BrBr.Cn1c(=O)c2[nH]cnc2n(C)c1=O>>Cn1c(=O)c2[nH]c(Br)nc2n(C)c1=O,,CC(=O)O,O,,,test
US20080207590A1,C1COCCN1.CCOC(=O)c1ccc(-c2ccc3c(c2)C(Cl)=Nc2ccccc2O3)cc1>>CCOC(=O)c1ccc(-c2ccc3c(c2)C(N2CCOCC2)=Nc2ccccc2O3)cc1,,CCOC(C)=O,Cc1ccccc1,,,test
US20070202174A1,CC(=O)N[C@@H](CS)C(=O)O.CC(C)(C)OC(=O)NCC#N.N>>CC(=O)O.N=C(N)CNC(=O)[O-],,CO,,,,test
US20060111375A1,C1CCNCC1.COc1cc2c(Oc3cc4cccnc4nc3C)ccnc2cc1O.ClCCBr>>COc1cc2c(Oc3cc4cccnc4nc3C)ccnc2cc1OCCN1CCCCC1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20070088070A1,CCOC(=O)c1ccc([C@H](C)n2nc(-c3cc(C(F)(F)F)ccc3OCC)cc2-c2ccc3cc(OC)ccc3c2)cc1>>CCOc1ccc(C(F)(F)F)cc1-c1cc(-c2ccc3cc(OC)ccc3c2)n([C@@H](C)c2ccc(C(=O)O)cc2)n1,,C1COCCO1,CO,Cl,[Na+].[OH-],test
US20090239845A1,Cc1cc(C=O)nn1Cc1cc(Cl)ccc1OCC(C)C.Nc1ccccc1N>>Cc1cc(-c2nc3ccccc3[nH]2)nn1Cc1cc(Cl)ccc1OCC(C)C,,CCOC(C)=O,CO,O=S([O-])O.[Na+],,test
US20150232428A1,O=[N+]([O-])c1cc(-c2ccc([C@@H](O)C(F)F)cc2)cc([N+](=O)[O-])c1>>Nc1cc(N)cc(-c2ccc([C@@H](O)C(F)F)cc2)c1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20090149441A1,C#C[Si](C)(C)C.O=C(Nc1ccccc1)c1cn2cc(I)ccc2n1>>C#Cc1ccc2nc(C(=O)Nc3ccccc3)cn2c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,[Cl-],[NH4+],C1CCNCC1,,test
US20040034005A1,BrC(Br)(Br)Br.O=[N+]([O-])c1cc(F)ccc1CCO>>O=[N+]([O-])c1cc(F)ccc1CCBr,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20030130238A1,CC(=O)Cl.COC(=O)C(CO)N(Cc1ccccc1N)S(=O)(=O)c1ccc(OC)cc1>>C=C(C(=O)OC)N(Cc1ccccc1NC(C)=O)S(=O)(=O)c1ccc(OC)cc1,,ClCCl,,CCN(CC)CC,,test
US20080032986A1,CCS.COc1cc(C(Nc2cccc3nc(C)ccc23)C2(C(F)(F)F)CO2)ccc1F>>CCSCC(O)(C(Nc1cccc2nc(C)ccc12)c1ccc(F)c(OC)c1)C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04419352,CCCc1c2nc(C(=O)OCC)ccc2cc2c(=O)cc(C(=O)OCC)oc12>>CCCc1c2nc(C(=O)O)ccc2cc2c(=O)cc(C(=O)O)oc12,,CO,,[Na+].[OH-],,test
US20160159814A1,C[C@H](OC(=O)c1ccccc1)c1cccc2c1C(F)(F)C(=O)N2C(=O)OC(C)(C)C>>C[C@H](OC(=O)c1ccccc1)c1cccc2c1C(F)(F)C(=O)N2,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20140031360A1,CC(C)(C)OC(=O)NC1CCN(c2cncc(-c3nn(C4CCCCO4)c4ccc(-c5cnc6[nH]nc(C(F)(F)F)c6c5)cc34)n2)CC1>>NC1CCN(c2cncc(-c3n[nH]c4ccc(-c5cnc6[nH]nc(C(F)(F)F)c6c5)cc34)n2)CC1,,C1COCCO1,,Cl,,test
US20100056502A1,O=c1ccc2cccc3c2n1CCC31CO1>>O=CC1CCn2c(=O)ccc3cccc1c32,,CC(C)=O,,,,test
US20090012138A1,CC#N.Clc1ccc(OC2CO2)cc1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCCCOc1ccc(Cl)cc1,,O,,[Cl-].[NH4+],,test
US20130225620A1,CC(C)(C)OC(=O)n1ccc2c(Cl)c(CN=C(c3ccccc3)c3ccccc3)ccc21.CI>>CC(N=C(c1ccccc1)c1ccccc1)c1ccc2c(ccn2C(=O)OC(C)(C)C)c1Cl,,C1CCOC1,CCOC(C)=O,CC(C)(C)[O-].[K+],,test
US20050014805A1,CCCCCI.CCOC(=O)c1nc(-c2ccc(SC(C)(C)C(=O)OC(C)(C)C)cc2)n[nH]1>>CCCCCn1nc(-c2ccc(SC(C)(C)C(=O)OC(C)(C)C)cc2)nc1C(=O)OCC,,CN(C)C=O,,[H-].[Na+],,test
US20130096125A1,Cc1ccc(N)c(C)c1.O=C(O)CBr.S=C=S>>Cc1ccc(N2C(=O)CSC2=S)c(C)c1,,CCOC(C)=O,,CCN(CC)CC,Cl,test
US20160200681A1,O=C1CCc2c1c[nH]c2Br.O=S(=O)(Cl)c1cccnc1>>O=C1CCc2c1cn(S(=O)(=O)c1cccnc1)c2Br,,CN(C)C=O,,O,[H-].[Na+],test
US20070299263A1,COc1cccc(CN(C[C@@H](O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)C(=O)OC(C)(C)C)c1>>COc1cccc(CN(C[C@@H](O)[C@@H](N)Cc2ccccc2)C(=O)OC(C)(C)C)c1,[Pd],CO,,[H][H],,test
US04577022,Cc1ccnc2c1CCCC2[Si](C)(C)C.[Li]CCCC>>[Li]C1([Si](C)(C)C)CCCc2c(C)ccnc21,,C1CCOC1,CCCCCC,,,test
US20100173901A1,CC1(C)OB(c2cnn(C3CCOCC3)c2)OC1(C)C.CC1Cc2ccc(Br)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1>>CC1Cc2ccc(-c3cnn(C4CCOCC4)c3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,O,C1COCCO1,O=C([O-])O.[Na+],test
US06355642B1,CI.O=C1Nc2cccc3cccc1c23>>CN1C(=O)c2cccc3cccc1c23,,CN(C)C=O,O,CCOC(C)=O,[H-].[Na+],test
US20130131016A1,C=C(C)B1OC(C)(C)C(C)(C)O1.Clc1cc(Br)cc(Cl)c1Cl>>C=C(C)c1cc(Cl)c(Cl)c(Cl)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20130296317A1,CSc1sc(-c2ccn(COCC[Si](C)(C)C)n2)c2c1C(=O)NCC2.Ic1ccccc1>>CSc1sc(-c2ccn(COCC[Si](C)(C)C)n2)c2c1C(=O)N(c1ccccc1)CC2,[Cu]I,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100048654A1,CC(=O)CCC(=O)N(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)[C@H](C(=O)O)C(C)C>>CC(O)CCC(=O)N(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)[C@H](C(=O)O)C(C)C,,CO,,[BH4-].[Na+],,test
US20090192203A1,BrBr.CCOC(=O)COc1ccc(OCc2nc(-c3ccc(C(F)(F)F)cc3)cs2)cc1C>>CCOC(=O)COc1cc(Br)c(OCc2nc(-c3ccc(C(F)(F)F)cc3)cs2)cc1C,,CC(=O)O,ClCCl,O,,test
US20070060626A1,CS(=O)(=O)Cl.Cc1cccc(-c2nc(C)c(CO)o2)c1>>Cc1cccc(-c2nc(C)c(COS(C)(=O)=O)o2)c1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20120040954A1,COc1cc(OC)c2c(=O)[nH]c(-c3ccc(N4CCNCC4)cc3)nc2c1.OCCBr>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(N4CCN(CCO)CC4)cc3)nc2c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05504244,CCCCCCCCc1ccccc1.N#Cc1cccc(CC(=O)O)c1>>CCCCCCCCc1ccc(C(=O)Cc2cccc(C#N)c2)cc1,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20150258074A1,CC(=O)Cl.OCc1nc(Cl)cc2c1c(OCc1ccccc1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(=O)OCc1nc(Cl)cc2c1c(OCc1ccccc1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160102071A1,CC#C[C@@H](CC(=O)OCC)c1ccc(OCc2ccc3scc(-c4ccc(S(C)(=O)=O)cc4C)c3c2)cc1>>CC#C[C@@H](CC(=O)O)c1ccc(OCc2ccc3scc(-c4ccc(S(C)(=O)=O)cc4C)c3c2)cc1,,CCO,,Cl,[Li+].[OH-],test
US05753660,C1CSCCN1.O=C(Cl)CCl>>O=C(CCl)N1CCSCC1,,ClCCl,,CCN(CC)CC,,test
US05489593,CCCNc1cccnc1N1CCNCC1.COc1ccc2[nH]c(C(=O)O)cc2c1.O=C(n1ccnc1)n1ccnc1>>CCOc1ccccc1N1CCN(C(=O)c2cc3cc(OC)ccc3[nH]2)CC1,,C1CCOC1,CCOCC,O=C([O-])O.[Na+],,test
US20070208064A1,CC(=O)Cl.CCOC(=O)CNc1ccc(C)cc1>>CCOC(=O)CN(C(C)=O)c1ccc(C)cc1,,C1CCOC1,,,,test
US20020001591A1,N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)OCc1ccccc1.O=C(Cl)C1CCCCC1>>O=C(N[C@@H](Cc1ccc(O)cc1)C(=O)O)C1CCCCC1,[Pd],C1CCOC1,CO,c1ccncc1,,test
US04647560,O=C(Cl)OCc1ccccc1.O=C1Nc2ccc(Cl)cc2C(c2ccccc2)=NC12CCN(Cc1ccccc1)CC2>>O=C(OCc1ccccc1)N1CCC2(CC1)N=C(c1ccccc1)c1cc(Cl)ccc1NC2=O,,Cc1ccccc1,ClC(Cl)Cl,O=C([O-])O.[Na+],,test
US20140274695A1,CCOC(COc1ccc(Br)c(F)c1)OCC>>Fc1c(Br)ccc2occc12,,Cc1ccccc1,,,,test
US05167857,CCCCCCOc1ccc(N=Nc2ccc(OC(=O)CCOCCCC)cc2)cc1.OO>>CCCCCCOc1ccc(N=[N+]([O-])c2ccc(OC(=O)CCOCCCC)cc2)cc1,,CC(=O)O,,O,,test
US09018175B2,CCOc1cc2c(cc1OC)C(c1cccc(C(=O)O)c1)=N[C@@H]1CCSC[C@H]21.CCn1nnc(Cn2c(=O)n(C3CCNCC3)c(=O)c3sc(-c4ccccc4)cc32)n1>>CCOc1cc2c(cc1OC)C(c1cccc(C(=O)N3CCC(n4c(=O)c5sc(-c6ccccc6)cc5n(Cc5nnn(CC)n5)c4=O)CC3)c1)=N[C@@H]1CCSC[C@H]21,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040014962A1,CCOC(=O)c1csc(N2CCC(O)CC2)n1.CS(=O)(=O)Cl>>CCOC(=O)c1csc(N2CCC(OS(C)(=O)=O)CC2)n1,,ClCCl,,CCN(CC)CC,CCO,test
US06013663,COC(=O)CCNC(=O)CCCCC1CCSS1>>O=C(O)CCNC(=O)CCCCC1CCSS1,,CO,,[Na+].[OH-],,test
US20070117839A1,C=CCC(=O)N1C(C=CC(=O)OCC)CN(C(=O)OC)CC1c1cc(F)c(F)c(F)c1>>COC(=O)N1C[C@@H]2C=CCC(=O)N2[C@H](c2cc(F)c(F)c(F)c2)C1,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,ClCCl,,CCN(CC)CC,,test
US20050288314A1,C[C@H](O)c1cccc(Cl)c1.N#Cc1c(F)cccc1F>>C[C@H](Oc1ccc(F)c(C#N)c1)c1cccc(Cl)c1,,CN(C)C=O,,[H-].[Na+],,test
US20080312226A1,O=C(Nc1cncnc1)OCC(Cl)(Cl)Cl.c1ccc(-c2csc(N3CCNCC3)n2)cc1>>O=C(Nc1cncnc1)N1CCN(c2nc(-c3ccccc3)cs2)CC1,,O,,CCN(C(C)C)C(C)C,CS(C)=O,test
US04665073,CCOC(=O)CCCSc1nccc(NC(N)=NCC(F)(F)F)n1>>NC(=NCC(F)(F)F)Nc1ccnc(SCCCC(=O)O)n1,,O,,CC(=O)O,[Na+].[OH-],test
US04963590,CCOC(=O)CN=C=O.O=C(C=Cc1cc(O)c(O)c([N+](=O)[O-])c1)c1ccccc1>>CCOC(=O)CNC(=O)Oc1cc(C=CC(=O)c2ccccc2)cc([N+](=O)[O-])c1O,,C1CCOC1,,,,test
US05514680,Nc1cc(F)c(F)cc1[N+](=O)[O-].O=C1CCC(=O)N1Cl>>Nc1c([N+](=O)[O-])cc(F)c(F)c1Cl,,CN(C)C=O,,O,,test
US20080096930A1,II.N#Cc1ccnc(Oc2cccc(CO)c2)c1>>N#Cc1ccnc(Oc2cccc(CI)c2)c1,,CCOC(C)=O,ClCCl,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090126932A1,C=CC(=O)Cl.OCc1ccco1>>C=CC(=O)OCc1ccco1,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US06908914B1,C#CCBr.C1N2CN3CN1CN(C2)C3.Cc1ccccc1>>C#CCN1CCCCCC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05026856,CCOC(=O)c1cn(C2CC2)c2nc(Cl)c(F)cc2c1=O.COc1cccc2c1CNC2>>COc1cccc2c1CN(c1nc3c(cc1F)c(=O)c(C(=O)O)cn3C1CC1)C2,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20060106048A1,CCS(=O)c1cc2c(c3c1OC(C)(C)C3)C(c1cccc(C(=O)NC(C)(C)C(N)=O)c1)=NC(C)(C)C2.O>>CCS(=O)(=O)c1cc2c(c3c1OC(C)(C)C3)C(c1cccc(C(=O)NC(C)(C)C(N)=O)c1)=NC(C)(C)C2,,CO,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20110269738A1,CCc1c(/C=C/OC)cccc1-c1nsc(-c2ccc(OC(C)C)c(Cl)c2)n1>>CCc1c(CC=O)cccc1-c1nsc(-c2ccc(OC(C)C)c(Cl)c2)n1,Cl,C1CCOC1,,,,test
US20110059948A1,CC(=O)c1cc(F)ccc1Oc1nc2ccc([N+](=O)[O-])cc2cc1Cc1ccccc1>>CC(=O)c1cc(F)ccc1Oc1nc2ccc(N)cc2cc1Cc1ccccc1,[Pd],CCOC(C)=O,,,,test
US20040147608A1,CC(C)CC1CC1(CNC(=O)OC(C)(C)C)C(=O)O.Cl>>CC(C)CC1CC1(CN)C(=O)O.Cl,,C1COCCO1,,CCOCC,,test
US20040006141A1,CCOC(=O)C(C)(Cc1ccc(OCc2ccccc2)cc1)Oc1ccc(C(C)C)cc1>>CCOC(=O)C(C)(Cc1ccc(O)cc1)Oc1ccc(C(C)C)cc1,[Pd],,,,,test
US20100105904A1,COc1cc(CN)ccc1-n1cnc(C)c1.C[C@H](NC(=O)Oc1ccccc1)c1ccc(F)cc1>>COc1cc(CNC(=O)N[C@@H](C)c2ccc(F)cc2)ccc1-n1cnc(C)c1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,O,test
US20090299072A1,BrCC1CCC1.COC(=O)Cc1ccc([N+](=O)[O-])c(OCC(F)(F)F)c1>>COC(=O)C(CC1CCC1)c1ccc([N+](=O)[O-])c(OCC(F)(F)F)c1,,CS(C)=O,,O,[K+].[OH-],test
US06627651B1,COC(=O)C1=Cc2cc(OCc3ccccc3OC)ccc2S(=O)(=O)CC1>>COc1ccccc1COc1ccc2c(c1)C=C(C(=O)O)CCS2(=O)=O,,C1CCOC1,CO,Cl,O=C([O-])[O-].[K+].[K+],test
US20060093960A1,C1CCOC1.O=CC1CC2C=CC1C2.OC(C(F)(F)F)C(F)(F)F>>OC(C1CC2C=CC1C2)C(F)(F)C(O)(O)C(F)(F)F,,CCCCCC,,Cl,[Li]CCCC,test
US20050075378A1,BrCc1ccccc1.CC(C)OC(=O)NCc1ccc(O)cc1CCC(=O)OC(C)(C)C>>CC(C)OC(=O)NCc1ccc(OCc2ccccc2)cc1CCC(=O)OC(C)(C)C,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120171229A1,COC(=O)C=C(C)C.COc1ccc(C)cc1O>>Cc1cccc2c1C(C)(C)CC(=O)O2,,CS(=O)(=O)O,,O,,test
US05994368,CC(=O)OC(C)=O.Cc1ccc2cccc(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)CSc4ccc(N)cc4)c3Cl)c2n1>>CC(=O)Nc1ccc(SCC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4ccc(C)nc34)c2Cl)cc1,,ClCCl,,,,test
US20050026968A1,COc1ccccc1CN.O=C(Cl)c1ccc([N+](=O)[O-])o1>>COc1ccccc1CNC(=O)c1ccc([N+](=O)[O-])o1,,CCN(CC)CC,ClCCl,,,test
US20060205715A1,CC(C)CCCN(CC1CCCc2c(Oc3ccc(C#N)cn3)cccc21)C(=O)OC(C)(C)C.OO>>CC(C)CCCN(CC1CCCc2c(Oc3ccc(C(N)=O)cn3)cccc21)C(=O)OC(C)(C)C,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090137557A1,CCC(C(=O)O)C1(C)OCCO1.NCCc1cccc(F)c1>>CCC(C(=O)NCCc1cccc(F)c1)C1(C)OCCO1,,ClCCl,,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20110263598A1,CC1(C)OB(/C=C/c2ccc(CCN3CCOCC3)cc2)OC1(C)C.COc1ccc2c(c1)[C@]1(C[C@H]1c1ccc3c(I)n[nH]c3c1)C(=O)N2>>COc1ccc2c(c1)[C@]1(C[C@H]1c1ccc3c(C=Cc4ccc(CCN5CCOCC5)cc4)n[nH]c3c1)C(=O)N2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20160214997A1,FC1(F)Oc2ccc3c(Cl)nc(Cl)nc3c2O1.NNC(=O)Cc1cccnc1Cl>>O=C(Cc1cccnc1Cl)NNc1nc(Cl)nc2c3c(ccc12)OC(F)(F)O3,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US04282245,CC(C(N)=O)c1ccc2c(c1)C(=O)Cc1cc(C(F)(F)F)ccc1S2.[OH-]>>CC(C(=O)O)c1ccc2c(c1)C(=O)Cc1cc(C(F)(F)F)ccc1S2,,O,,CCO,,test
US07262201B1,COc1cc2c(Cl)ncnc2cc1OCC1CCN(C)CC1.COc1ccc(C2=NN=C(N)C2)cc1.Cl>>COc1ccc(-c2cc(Nc3ncnc4cc(OCC5CCN(C)CC5)c(OC)cc34)n[nH]2)cc1.Cl,,CC(C)O,,,,test
US20160145199A1,N#CC#Cc1ccc(N)cc1.S=C(Cl)Cl>>N#CC#Cc1ccc(N=C=S)cc1,,O,,ClCCl,O=C([O-])O.[Na+],test
US20050113397A1,C1CNCCN1.Cc1c(-c2ccccc2)c(Cl)n2c(nc3ccccc32)c1C#N>>Cc1c(-c2ccccc2)c(N2CCNCC2)n2c(nc3ccccc32)c1C#N,,CS(C)=O,,CCN(CC)CC,O,test
US20130079335A1,CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21>>CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(O)ccc2-n2c(C)nnc21,,ClCCl,,BrB(Br)Br,,test
US20120101100A1,CCNC(=O)Nc1cc(CO)c(Br)cn1.CCOC(=O)c1cncc(B2OC(C)(C)C(C)(C)O2)c1>>CCNC(=O)Nc1cc(CO)c(-c2cncc(C(=O)OCC)c2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120178765A1,COC(=O)c1cc(CO)cc(OCc2ccccc2C)c1.O=P(OBr)(OBr)OBr>>COC(=O)c1cc(CBr)cc(OCc2ccccc2C)c1,,C1CCOC1,,,,test
US05039675,CC1CC(=O)NN=C1c1ccc(NC(=O)CCCN2C(=O)c3ccccc3C2=O)c(N)c1>>CC1CC(=O)NN=C1c1ccc2[nH]c(CCCN3C(=O)c4ccccc4C3=O)nc2c1,,CC(=O)O,,,,test
US06756373B1,CC(C)CO.O=C(O)c1cccnc1Cl>>CC(C)COc1ncccc1C(=O)O,,CC(C)CO,,[Na],,test
US20010021718A1,CCCS(=O)(=O)Cc1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1>>CCCS(=O)(=O)Cc1noc([C@H](CCCC2CCCCC2)CC(=O)O)n1,,C1COCCO1,Cl,,,test
US20060148858A1,CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO.COC(=O)Cc1cccc(OC)c1O>>CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCOc1c(CC(=O)O)cccc1OC,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US04176184,COc1ccc(SC)cc1C1=NC2=C3C=NC(C)(C)C(=O)C3CC(=O)C2=N1.OO>>COc1ccc(S(C)=O)cc1C1=NC2=C3C=NC(C)(C)C(=O)C3CC(=O)C2=N1,,CC(=O)O,O,O=C([O-])[O-].[K+].[K+],,test
US20150025070A1,COc1ccc(-c2nnc(C3CCN(CC(=O)O)CC3)o2)cc1.NCc1nc2c(c(=O)[nH]1)COCC2>>COc1ccc(-c2nnc(C3CCN(CC(=O)NCc4nc5c(c(=O)[nH]4)COCC5)CC3)o2)cc1,,CC#N,,,,test
US20110020460A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Cl.NN>>CC(C)(C)OC(=O)N1CCC(NN)CC1.Cl,[Pt],CO,O,[H][H],,test
US20140243336A1,CC(C)(C)OC(=O)NC(CNC(=O)OCc1ccccc1)C(F)F.O=C(O)C(=O)O>>CC(C)(C)OC(=O)NC(CN)C(F)F.O=C(O)C(=O)O,[Pd],CO,ClCCl,,,test
US20140206663A1,C[C@H]1C(=O)NN=C2COc3cc(C(F)(F)F)c(NC4CN(C(=O)OC(C)(C)C)C4)cc3N21.O=C(O)C(F)(F)F>>C[C@H]1C(=O)NN=C2COc3cc(C(F)(F)F)c(NC4CNC4)cc3N21.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20100035985A1,CC(C#N)=C[C@@H]1[C@@H](C(=O)O)C1(C)C.Cc1c(F)c(F)c(CO)c(F)c1F>>CC(C#N)=C[C@@H]1[C@@H](C(=O)OCc2c(F)c(F)c(C)c(F)c2F)C1(C)C,CN(C)c1ccncc1,ClCCl,,,,test
US20010031778A1,CCOC(=O)c1ccc(Cl)nc1.OCC(F)(F)C(F)F>>CCOC(=O)c1ccc(OCC(F)(F)C(F)F)nc1,,CCCCCC,CN(C)C=O,[H][H],[H-].[Na+],test
US20130317235A1,N[C@H](C(=O)O)C12CC3CC(CC(O)(C3)C1)C2.O=C(Cl)OCc1ccccc1>>O=C(N[C@H](C(=O)O)C12CC3CC(CC(O)(C3)C1)C2)OCc1ccccc1,,O,,Cl,[Na+].[OH-],test
US05593984,Brc1ccn2ccncc12.N#C[Cu]>>N#Cc1ccn2ccncc12,,CN1CCCC1=O,,O,,test
US20120263670A1,C=C(C)C(=O)Cl.C[Si](C)(C)CC#CO>>C=C(C)C(=O)OCC#C[Si](C)(C)C,,CCOCC,,CCN(CC)CC,,test
US20050143422A1,COc1c(Br)ccc2oc(C(=O)O)c(C)c12>>COc1c(Br)ccc2oc(CO)c(C)c12,,C1CCOC1,,B,,test
US05028608,C#CCCC(=O)N[C@@H](CCC(=O)OC)C(=O)OC.CC(C)(C)C(=O)Nc1cc2c(O)n(I)cnc-2n1>>COC(=O)CC[C@H](NC(=O)CCC#Cn1cnc2nc(NC(=O)C(C)(C)C)cc-2c1O)C(=O)OC,[Cu]I,CN(C)C=O,,CCN(CC)CC,O,test
US20140163220A1,CC#N.COc1cc(Br)c(CBr)cc1OC>>COc1cc(Br)c(CCC#N)cc1OC,,C1CCOC1,,O,[Li]CCCC,test
US20010027196A1,CS(=O)(=O)c1nc(N)nc(-c2ccc3c(c2)OCO3)c1C#N.NCCCc1ccccc1>>N#Cc1c(NCCCc2ccccc2)nc(N)nc1-c1ccc2c(c1)OCO2,,COCCOC,,,,test
US20150045378A1,CCOC(=O)C=Cc1cc(OC(=O)OC)ccc1OC>>CCOC(=O)CCc1cc(OC(=O)OC)ccc1OC,[Pd],CO,,,,test
US20140194383A1,CCOC(=O)c1cccc(N2CC(C)=C(C)C2)c1.C[N+]1([O-])CCOCC1.O=[Os](=O)(=O)=O>>CCOC(=O)c1cccc(N2CC(C)(O)C(C)(O)C2)c1,O=[Os](=O)(=O)=O,C1CCOC1,,O,,test
US06248739B1,BrCCBr.O=C(NCc1ccc(Cl)cc1)c1cnc2ccc(C#CCO)cc2c1O>>C=Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(C#CCO)ccc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060287341A1,NNc1nc(Cl)nc(-c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]nc2c(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)nc(-n3ccnc3)n12,,CCOC(C)=O,O,C1CCOC1,,test
US04728355,Nc1ccnnc1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ccnnc1)Oc1ccccc1,,C1CCOC1,,CCN(CC)CC,,test
US04661505,CC(=O)c1ccc(O)cc1O.CCCC(Br)CCCCC(=O)OC>>CCCC(CCCCC(=O)O)Oc1ccc(C(C)=O)c(O)c1,,CCC(C)=O,,,,test
US05284852,CCCCc1nc(=O)c2cc(C=O)ccc2[nH]1.CC[Mg]Br>>CCCCc1nc(=O)c2cc(C(O)CC)ccc2[nH]1,,C1CCOC1,,,,test
US20050065118A1,ClCc1ccc(-c2ccccc2)cc1.Nc1cccc(S)c1>>Nc1cccc(SCc2ccc(-c3ccccc3)cc2)c1,,CCCCCC,CCOC(C)=O,,,test
US05606063,CCCCN=C=O.Nc1ccc(S(N)(=O)=O)c(Cl)c1.O=C(Cl)C(=O)Cl>>O=C=Nc1ccc(S(=O)(=O)N=C=O)c(Cl)c1,,Clc1ccccc1,,,,test
US05998415,CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)C(=S)C1>>S=C1CNCCN1Cc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140155415A1,CSc1ccccc1C(N)c1cc2ccccc2s1.O=S(=O)(Cl)c1ccc2c(c1)OCCO2>>CSc1ccccc1C(NS(=O)(=O)c1ccc2c(c1)OCCO2)c1cc2ccccc2s1,,ClCCCl,,CCN(C(C)C)C(C)C,,test
US20070088040A1,CC#N.CCN(C(C)C)C(C)C.CCOC(=O)c1cn(Cc2ccc(OC)cc2OC)c2nc(Cl)c(F)cc2c1=O.O>>CCOC(=O)c1cn(Cc2ccc(OC)cc2OC)c2nc(N3CC[C@H]3CO)ccc2c1=O,,CC#N,,,,test
US20160137653A1,N#Cc1ccc(C(=O)Cl)cc1.NC[C@H]1CC[C@@H](c2ccccc2)CC1>>N#Cc1ccc(C(=O)NC[C@H]2CC[C@@H](c3ccccc3)CC2)cc1,,ClCCl,,CCN(CC)CC,,test
US20020193269A1,CCCCCCCC(=O)CCC(=O)O.O=S(Cl)Cl>>CCCCCCCC(=O)CCC(=O)Cl,,CCOCC,,c1ccncc1,,test
US20140179743A1,CCOc1ccc(CC2SC(=O)N(CCNC(=O)OC(C)(C)C)C2=O)cc1>>CCOc1ccc(CC2SC(=O)N(CCN)C2=O)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20120196864A1,BrCC1CCCCC1.O=Cc1ccc(OCc2ccc(C(F)(F)F)cc2C(F)(F)F)c(O)c1>>O=Cc1ccc(OCc2ccc(C(F)(F)F)cc2C(F)(F)F)c(OCC2CCCCC2)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130123438A1,C=C(C)C(=O)OCCCCCCCCO.O=C(Cl)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>C=C(C)C(=O)OCCCCCCCCOC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1,,ClCCl,,Cl,c1ccncc1,test
US20160185759A1,NC(=O)c1n[nH]c2ccc(Cl)cc12>>N#Cc1n[nH]c2ccc(Cl)cc12,,c1ccncc1,,ClCCl,O=C(O)C(F)(F)F,test
US04618683,COS(=O)(=O)OC.COc1ccc(Br)c(C=O)c1O>>COc1ccc(Br)c(C=O)c1OC,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20060014663A1,CC(O)C1C=CCCCCC1>>CC(=O)C1C=CCCCCC1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20030158202A1,CN1CCN(c2nc(N)cc3ccccc23)CC1.ClCCl.O=S(=O)(Cl)c1ccccc1>>CN1CCN(c2nc(NS(=O)(=O)c3ccccc3)cc3ccccc23)CC1.Cl,,ClCCl,,c1ccncc1,,test
US06372766B1,Cc1cc(I)cnc1N.ClCl>>Cc1cc(I)cnc1Cl,,O,,Cl,O=N[O-].[Na+],test
US20160152598A1,COC(=O)c1cc(Cc2ccc(-c3cn(C)nc3C)nc2)c(C)cc1O.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1cc(Cc2ccc(-c3cn(C)nc3C)nc2)c(C)cc1OS(=O)(=O)C(F)(F)F,,CN(C)C=O,,Cl,[H-].[Na+],test
US20090181956A1,Cc1cc(Cl)cc(C(=O)O)c1N.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>Cc1cc(Cl)cc2c(=O)oc(=O)[nH]c12,,C1CCOC1,,,,test
US20160096833A1,CC(C)[Si](Cl)(C(C)C)C(C)C.Nc1ncc(Br)cc1CO>>CC(C)[Si](OCc1cc(Br)cnc1N)(C(C)C)C(C)C,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US20080287458A1,CC(C)(O)CN.O=Cc1ccc(S(=O)(=O)Cl)cc1>>CC(C)(O)CNS(=O)(=O)c1ccc(C=O)cc1,,CO,,O=C([O-])O.[Na+],,test
US20150299220A1,CC1(C)CC(C(=O)O)N(C(=O)OC(C)(C)C)C1.O=C1CCC(=O)N1O>>CC1(C)CC(C(=O)ON2C(=O)CCC2=O)N(C(=O)OC(C)(C)C)C1,,C1CCOC1,,CC(C)N=C=NC(C)C,,test
US07642276B2,NC1CC1.ON=C(Cl)c1ccc(Br)cc1F>>ON=C(NC1CC1)c1ccc(Br)cc1F,,CCOCC,,,,test
US20060063759A1,ClC(Cl)(Cl)C(Cl)(Cl)Cl.Nc1cccc(C=C2c3ccc(Cl)cc3CCc3sccc32)c1>>Nc1cccc(C=C2c3ccc(Cl)cc3CCc3sc(Cl)cc32)c1,,C1CCOC1,,[Li]CCCC,,test
US20050010052A1,C=Cc1cc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c(Cl)cn1.CC(=O)O>>O=Cc1cc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c(Cl)cn1,,ClCCl,,,,test
US04018768,CO.Clc1nnnc2c1sc1ccccc12>>COc1nnnc2c1sc1ccccc12,,CO,,C[O-].[Na+],,test
US20160272617A1,COC(=O)c1cc(N)cc2[nH]ncc12.Cc1cc(C(=O)NC2CCC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)O)cc1>>COC(=O)c1cc(NC(=O)[C@H](Cc2ccc(-c3ccc(C(=O)NC(C)C)cc3C)cc2)NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)cc2[nH]ncc12,,CCOC(C)=O,CS(C)=O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20050222261A1,CCNCc1ccc(F)cc1.COC(=O)c1ccccc1OCCc1ccc(OCC(=O)Cl)cc1>>CCN(Cc1ccc(F)cc1)C(=O)COc1ccc(CCOc2ccccc2C(=O)OC)cc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20080004309A1,CCCC[Sn](CCCC)(CCCC)CCCC.CCOC(=O)c1nc(Br)c2nc(C(C)(C)C)sc2c1O>>CCCCc1nc(C(=O)OCC)c(O)c2sc(C(C)(C)C)nc12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,CN(C)C=O,,,test
US20030045540A1,COC(=O)c1cc2cscc2cn1>>O=C(O)c1cc2cscc2cn1,,CO,O,[Na+].[OH-],,test
US04277394,CC(=O)O.NNC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1>>CC(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1,,C1CCOC1,,,,test
US20140371204A1,C=O.O=C(Cn1cnc2c1CCNC2)OCc1ccccc1>>CN1CCc2c(ncn2CC(=O)OCc2ccccc2)C1,,CO,ClCCl,CC(=O)O,[BH3-]C#N.[Na+],test
US20110034334A1,COC(=O)c1cccnc1N.O=C(O)Cc1ccc(Cl)cc1Cl>>COC(=O)c1cccnc1NC(=O)Cc1ccc(Cl)cc1Cl,CN(C)c1ccncc1,ClCCl,c1ccncc1,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20080045532A1,C1CCNC1.O=C(O)c1ccc(-n2nc(C(F)(F)F)c3c2CCCC3)cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>O=C(Nc1ccc(-n2nc(C(F)(F)F)c3c2CCCC3)cc1)N1CCCC1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20080161303A1,CC(C)Nc1nnc2cc(Br)ccn12.Cc1ccc(C(=O)NC2CC2)cc1B1OC(C)(C)C(C)(C)O1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccn2c(NC(C)C)nnc2c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US06069141,CC(=O)NCC1CC(c2ccc(-n3ccc(C=O)c3)c(F)c2)=NO1.NO>>CC(=O)NCC1CC(c2ccc(-n3ccc(C=NO)c3)c(F)c2)=NO1,,CCO,O,Cl,[Na+].[OH-],test
US20100286125A1,CCCC[C@@H](C[C@@H](OC)c1ccc(F)cc1)C(=O)NOC1CCCCO1>>CCCC[C@@H](C[C@@H](OC)c1ccc(F)cc1)C(=O)NO,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040072818A1,Clc1ccc2c(N3CCNCC3)ccnc2c1.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)N1CCN(c2ccnc3cc(Cl)ccc23)CC1,,C1CCOC1,,CCCCCC,CCOC(C)=O,test
US20100273819A1,COC(=O)C(C)(C)Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)c(F)cc2C)C12C(=O)Nc1cc(Cl)ccc12.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>COC(=O)C(C)(C)Oc1ccc(Cl)cc1C1CC(=S)NC(c2cc(F)c(F)cc2C)C12C(=O)Nc1cc(Cl)ccc12,,C1CCOC1,Cc1ccccc1,,,test
US06107458,CCCCCC#Cc1ccc2cc(C(=O)OC)ccc2c1>>CCCCCCCc1ccc2cc(C(=O)OC)ccc2c1,O=[Pt],C1CCOC1,,[H][H],,test
US05942544,COC(=O)C=C(C=Cc1ccc([N+](=O)[O-])cc1)c1cccc(C#N)c1>>COC(=O)CC(CCc1ccc(N)cc1)c1cccc(C#N)c1,,C1CCOC1,,,,test
US20100093694A1,CC(C)(C)OC(=O)NN.CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NC4(C(=O)O)CC4)ccc3C)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NC4(C(=O)NNC(=O)OC(C)(C)C)CC4)ccc3C)cc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20050113580A1,COC(=O)Cc1cccc(OCCCBr)c1.NCc1cccc(C(F)(F)F)c1Cl>>COC(=O)Cc1cccc(OCCCNCc2cccc(C(F)(F)F)c2Cl)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150336949A1,COc1ccc(-c2cc3c(-c4c(C)nn(Cc5cccc(F)c5)c4C)cn(C(=O)OC(C)(C)C)c3nc2C2CC2)cc1N(C(=O)OC(C)(C)C)S(C)(=O)=O>>COc1ccc(-c2cc3c(-c4c(C)nn(Cc5cccc(F)c5)c4C)c[nH]c3nc2C2CC2)cc1NS(C)(=O)=O,,C1COCCO1,Cl,,,test
US20040259911A1,CC(C)(C)C(=O)Cl.CCCCOC(=O)c1ccc2ccc(C)nc2c1O>>CCCCOC(=O)c1ccc2ccc(C)nc2c1OC(=O)C(C)(C)C,,c1ccncc1,,,,test
US03931204,C1COCCN1.CC(C)Nc1nc(Cl)nc2cscc12>>CC(C)Nc1nc(N2CCOCC2)nc2cscc12,,O,,,,test
US20120208819A1,COC(=O)C[C@@H](Nc1ncc(C#N)cc1C(=O)N[C@@H](C)c1ccc(F)cc1)c1ccc(-c2cn(S(=O)(=O)c3ccccc3)c3ncnc(N)c23)cc1>>COC(=O)C[C@@H](Nc1ncc(C#N)cc1C(=O)N[C@@H](C)c1ccc(F)cc1)c1ccc(-c2c[nH]c3ncnc(N)c23)cc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20050282796A1,CI.O=C(c1ccccc1)N1CCC2c3cccc4c3N(CCC4O)C2CC1>>COC1CCN2c3c1cccc3C1CCN(C(=O)c3ccccc3)CCC12,,CN(C)C=O,,[H-].[Na+],,test
US04271164,Cc1ncc(C=O)c(N)n1.N#CCc1c(Cl)cccc1Cl>>Cc1ncc2cc(-c3c(Cl)cccc3Cl)c(N)nc2n1,,CCO,,[Na],,test
US06380215B1,CCOC(=O)[C@H](CN=[N+]=[N-])NC(=O)OC(C)(C)C>>CCOC(=O)[C@H](CN)NC(=O)OC(C)(C)C,[Pd],CCO,,,,test
US20070265265A1,NC1CCCC1.O=C(CBr)c1ccc(S(=O)(=O)Cl)cc1>>O=C(CBr)c1ccc(S(=O)(=O)NC2CCCC2)cc1,,ClCCl,,CCN(CC)CC,,test
US20090136472A1,CI.Cc1ccc(N=C2NC(=O)C(Cc3cccc(C(F)(F)F)c3)S2)cc1>>Cc1ccc(N=C2SC(Cc3cccc(C(F)(F)F)c3)C(=O)N2C)cc1,,CN(C)C=O,ClCCl,O=C([O-])[O-].[Na+].[Na+],,test
US20110071144A1,CNCCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1OC.CS(=O)(=O)Cl>>Cl.c1ccc2ncncc2c1,,ClCCl,,CCN(CC)CC,,test
US20130289049A1,COc1cc(C)c(S(=O)(=O)N(C)CCOCC(=O)N(C)[C@@H]2CCC[C@H](N3CCN(C)CC3)C2)c(C)c1.O=C(O)[C@@H](O)[C@H](O)C(=O)O>>COc1cc(C)c(S(=O)(=O)N(C)CCOCC(=O)N(C)[C@@H]2CCC[C@H](N3CCN(C)CC3)C2)c(C)c1.O=C([O-])[C@@H](O)[C@H](O)C(=O)[O-],,CC(C)=O,,CCO,,test
US20020099007A1,CCOC(=O)CCCCCBr.COc1cccc(C2CCCCC2=O)c1>>CCOC(=O)CCCCC1(c2cccc(OC)c2)CCCCC1=O,,CN(C)C=O,,[H-].[Na+],,test
US20140256715A1,O=P(Cl)(Cl)Cl.Oc1ncnc2cc(C(F)(F)F)cnc12>>FC(F)(F)c1cnc2c(Cl)ncnc2c1,,CCOC(C)=O,Cc1ccccc1,CCN(C(C)C)C(C)C,O,test
US04734418,C1CNCCN1.O=[N+]([O-])c1cnc(Cl)c([N+](=O)[O-])c1>>O=[N+]([O-])c1cnc(N2CCNCC2)c([N+](=O)[O-])c1,,CCCCO,,,,test
US20070185133A1,CC(C)(C)OC(=O)NCCN1C(=O)NCC1(C)C>>CC1(C)CNC(=O)N1CCN,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150025087A1,CC(c1c(F)cccc1F)n1cc(C(=O)O)c2ncccc21.NCCF>>CC(c1c(F)cccc1F)n1cc(C(=O)NCCF)c2ncccc21,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US06350735B1,N.N#Cc1nc(NCc2cccc3ccccc23)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1>>N.NCc1nc(NCc2cccc3ccccc23)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1,[Pd],CCO,,[H][H],,test
US05807892,O=C1C[C@H]2[C@H](C[C@@H](O)[C@@H]2/C=C/[C@H](O)C2CCCCC2)O1>>O=C1C[C@H]2[C@H](C[C@@H](O)[C@@H]2CC[C@H](O)C2CCCCC2)O1,[Pd],ClCCl,,CCOC(C)=O,,test
US20070275090A1,CC1=CC(=C(C#N)C#N)C=C(C)N1CCOCCCl.c1ccncc1>>CC1=CC(=C(C#N)C#N)C=C(C)N1CCOCC[n+]1ccccc1.[Cl-],,O,c1ccncc1,,,test
US20140113901A1,COC(=O)CBr.NC1(c2ccc(-c3nc4ccc(O)nn4c3-c3ccccc3)cc2)CCC1>>COC(=O)COc1ccc2nc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)n2n1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090076280A1,O=C1OCC[C@@H]1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=C1OCC[C@@H]1OS(=O)(=O)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US20130112921A1,O=C(c1cccc(Br)c1)c1cc(-c2ccccc2)cc(-c2ccccc2)c1.OB(O)C=Cc1ccccc1>>C=Cc1ccc(-c2cccc(C(=O)c3cc(-c4ccccc4)cc(-c4ccccc4)c3)c2)cc1,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20110152296A1,CC(O)c1cc2ncc(F)cc2nc1-c1ccccc1S(C)(=O)=O>>CS(=O)(=O)c1ccccc1-c1nc2cc(F)cnc2cc1C=O,,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20150126498A1,COc1cc(N)cnc1C.O=S(=O)(Cl)c1cccnc1Cl>>COc1cc(NS(=O)(=O)c2cccnc2Cl)cnc1C,,ClCCl,,c1ccncc1,,test
US20090042890A1,CCOC(=O)c1nc(Nc2ccc(CO)cc2)nc(Nc2ccccc2OC)c1N.CCOC(=O)c1nc(Nc2ccc(Cn3ccnc3)cc2)nc2c1[nH]c(=O)n2-c1ccccc1OC>>COc1ccccc1-n1c(=O)[nH]c2c(C(N)=O)nc(Nc3ccc(Cn4ccnc4)cc3)nc21,,ClCCl,,,,test
US05338745,BrCBr.O=C(CCc1ccc(O)c(O)c1)N1CCCC1>>O=C(CCc1ccc2c(c1)OCO2)N1CCCC1,,CN(C)C=O,,O,,test
US20130252972A1,CC(O)(c1cccnc1)c1c(-c2ccc(Cl)cc2)noc1-c1ccccc1.CI>>COC(C)(c1cccnc1)c1c(-c2ccc(Cl)cc2)noc1-c1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20160052884A1,CCC1(C=C(C(=O)OC(C)(C)C)n2cc(OC)c(-c3cc(Cl)ccc3C#N)cc2=O)COC1>>CCC1(CC(C(=O)OC(C)(C)C)n2cc(OC)c(-c3cc(Cl)ccc3C#N)cc2=O)COC1,,[Cl-],[NH4+],,,test
US06689922B1,CC(C)(O)CCCCCc1cccc(C#Cc2ccc(CO[Si](C)(C)C(C)(C)C)c(CO[Si](C)(C)C(C)(C)C)c2)c1>>CC(C)(O)CCCCCc1cccc(C#Cc2ccc(CO)c(CO)c2)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20160090381A1,CC(C)[C@@H]1COC(=O)N1C(=O)[C@H](C)C1CCCC1.[Li]O>>C[C@@H](C(=O)O)C1CCCC1,,C1CCOC1,O,OO,,test
US20140187584A1,CC1(N2Cc3c(cccc3[N+](=O)[O-])C2=O)CCC(=O)NC1=O>>CC1(N2Cc3c(N)cccc3C2=O)CCC(=O)NC1=O,[Pd],CO,,[H][H],,test
US20100261736A1,CC(C)(C)OC(=O)CBr.CCc1ccc(-c2c(-c3ccccc3)oc3nccc(OCCCO)c23)cc1>>CCc1ccc(-c2c(-c3ccccc3)oc3nccc(OCCCOCC(=O)OC(C)(C)C)c23)cc1,,CCCCCC,CN(C)C=O,Cl,O,test
US20090181942A1,CCOC(=O)CC(O)CC1OC(c2cccc(OC)c2OC)c2cc(Cl)ccc2-n2cccc21>>COc1cccc(C2OC(CC(O)CC(=O)O)c3cccn3-c3ccc(Cl)cc32)c1OC,,CCO,O,Cl,[Na+].[OH-],test
US20160237067A1,Cc1c(F)cc(C(=O)NC(C)C)cc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1.Cl>>Cc1c(F)cc(C(=O)NC(C)C)cc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1.Cl,,C1COCCO1,,,,test
US20070066618A1,CCc1nc2cc(Cl)c(Cl)cc2n1-c1ccc([C@H]2C[C@H](O)C2)cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CCc1nc2cc(Cl)c(Cl)cc2n1-c1ccc([C@@H]2C[C@H](N=[N+]=[N-])C2)cc1,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040158067A1,CCC[Mg]Cl.CCOc1cc(-c2c(CC)cccc2CC)ncc1C=O>>CCCC(O)c1cnc(-c2c(CC)cccc2CC)cc1OCC,,CCOCC,,[Cl-].[NH4+],,test
US20100216837A1,CN(C)C1(C#N)CCCC1.[Li]c1cccs1>>CN(C)C1(C(N)c2cccs2)CCCC1,,C1CCOC1,CO,[BH4-].[Na+],,test
US05849666,COC(=O)c1ccc(NNC(=O)C(C)C)cc1S(=O)(=O)NC(C)(C)C>>COC(=O)c1ccc(NNC(=O)C(C)C)cc1S(N)(=O)=O,,O=C(O)C(F)(F)F,,,,test
US20110313196A1,NC(=O)/C=C/c1cc(F)cc(C(F)(F)F)c1>>NC(=O)CCc1cc(F)cc(C(F)(F)F)c1,[Ni],CCO,,[H][H],,test
US06469021B1,ClCc1cc2c3ccccc3n(Cc3cc(Cl)ccc3Cl)c2cn1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCc1cc2c3ccccc3n(Cc3cc(Cl)ccc3Cl)c2cn1,,CCO,ClCCl,Cl,,test
US20160024103A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(CC(=O)O)c(-c3ccc(F)c(C(=O)NC45CC(C4)C5)c3)cc12.[NH4+]>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(CC(N)=O)c(-c3ccc(F)c(C(=O)NC45CC(C4)C5)c3)cc12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090192138A1,CN(C)C(=O)c1c(N2CCCN(C(=O)OC(C)(C)C)CC2)n(Cc2ccccc2)c2c(=O)n(C)c(=O)n(C)c12>>CN(C)C(=O)c1c(N2CCCN(C(=O)OC(C)(C)C)CC2)[nH]c2c(=O)n(C)c(=O)n(C)c12,[Pd],,,O=C[O-].[NH4+],,test
US20140378446A1,CI.COc1ccc([N+](=O)[O-])cc1NC(=O)OC(C)(C)C>>COc1ccc([N+](=O)[O-])cc1N(C)C(=O)OC(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20070083045A1,CC(C)(C)OC(=O)NC1(C(N)=O)CCOCC1>>CC(C)(C)OC(=O)NC1(C#N)CCOCC1,,ClCCl,,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US20070244104A1,C#CC1(O)CCCCC1.CI>>C#CC1(OC)CCCCC1,,CN(C)C=O,,[H-].[Na+],,test
US04544657,COc1ccccc1NCCN(Cc1ccccc1)Cc1ccccc1.O=C(Cl)CCl>>COc1ccccc1N1CCN(Cc2ccccc2)CC1=O,,ClCCl,,O,O=C([O-])[O-].[Na+].[Na+],test
US20100063054A1,COC(=O)C1=CN(CC(N)=O)C(NS(=O)(=O)c2ccc(C)cc2)C=C1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1ccc2nc(NC(=O)C(F)(F)F)cn2c1,,ClCCl,,,,test
US20100113502A1,BrCc1ccccc1.CC1CCN(C(=O)c2ccc3[nH]c4c(c3c2)CN(C(C)C)CC4)CC1>>CC1CCN(C(=O)c2ccc3c(c2)c2c(n3Cc3ccccc3)CCN(C(C)C)C2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20150315198A1,Cc1ccc2cc(CO)cnc2c1.O=S(Cl)Cl>>Cc1ccc2cc(CCl)cnc2c1,,ClCCl,,,,test
US20020151550A1,COc1ccc(C(=O)N(CCC(C)C)Cc2nc3ccccc3n2Cc2ccccc2O)c(Cl)c1OC.ClCCCI>>COc1ccc(C(=O)N(CCC(C)C)Cc2nc3ccccc3n2Cc2ccccc2OCCCCl)c(Cl)c1OC,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100144710A1,CCCCc1ccc(NS(C)(=O)=O)cc1.N#Cc1cccnc1N1CCN(C(=O)CCl)CC1>>CCCCc1ccc(N(CC(=O)N2CCN(c3ncccc3C#N)CC2)S(C)(=O)=O)cc1,,CC#N,CCOC(C)=O,[I-].[K+],,test
US04024183,Nc1cccc(N)c1.S=C=Nc1ccc(Cl)cc1>>Nc1cccc(NC(=S)Nc2ccc(Cl)cc2)c1,,ClC(Cl)Cl,,,,test
US20160108059A1,CC(C)NCC(NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C.O=C(O)c1oc(COC2CCCCO2)cc(=O)c1OCc1ccccc1>>CC(C)N(CC(NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)c1oc(COC2CCCCO2)cc(=O)c1OCc1ccccc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100061928A1,CCN(CC)CCNC(=O)c1ccc2cc(I)ccc2c1.COC(=O)c1ccc(I)c2c(=O)c3ccccc3[nH]c12>>CCN(CC)CCNC(=O)c1ccc(I)c2c(=O)c3ccccc3[nH]c12,,CCO,ClCCl,[Br-].[K+],,test
US20100120884A1,NC1(C(F)(F)F)CC1.O=C1CCC(=O)O1>>O=C(O)CCC(=O)NC1(C(F)(F)F)CC1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US04477629,CC(C)(c1ccc(O)cc1)c1ccc(O)cc1.CC(C)=O.N#CBr.N#CBr.O>>CC(C)(c1ccc(O)cc1)c1ccc(O)cc1.N#C[O-].N#C[O-],,CC(C)=O,O,CCN(CC)CC,,test
US20040102450A1,CC(C)(C)OC(=O)n1c(CN2CCN(Cc3ccc(-c4ccc(Cl)s4)cc3)CC2=O)cc2cnccc21>>O=C1CN(Cc2ccc(-c3ccc(Cl)s3)cc2)CCN1Cc1cc2cnccc2[nH]1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20120142625A1,CC1(C)O[C@@H]2[C@H](O1)[C@@H](CN)O[C@H]2n1cnc2c(N)ncnc21.COC(=O)C1CC(=O)C1>>COC(=O)[C@@H]1C[C@@H](NC[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@@H]3OC(C)(C)O[C@@H]32)C1,,CO,,[BH3-]C#N.[Na+],,test
US20100267746A1,C[C@H](CCCCCCCCCCNC(=O)OCc1ccccc1)NCC(O)c1ccc(O)c(NC=O)c1>>CC(CCCCCCCCCCN)NC[C@H](O)c1ccc(O)c(NC=O)c1,[Pd],CO,,[H][H],,test
US20040092582A1,COc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(N)cc1)=NC(C)(C)C2.O=C(Cl)c1cccnc1>>COc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(NC(=O)c3cccnc3)cc1)=NC(C)(C)C2,CN(C)c1ccncc1,CN(C)C=O,,Cl,O,test
US20140288326A1,C=C(C)C1CCCCC1=O.CCCCCC=NOCC>>CCCCCC1CC(C)=CCCCCC(=O)N1OC,,ClCCCl,,Cl[Sn](Cl)(Cl)Cl,,test
US20150353488A1,C[C@@H]1CCCN1CCc1ccc(B(O)O)cc1.OCCc1ccc(Br)cc1>>C[C@@H]1CCCN1CCc1ccc(-c2ccc(CCO)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20120321559A1,COc1cccc(C(CN)c2ccc(Br)cc2)c1.O=C1CCC(=O)O1>>COc1cccc(C(CNC(=O)CCC(=O)O)c2ccc(Br)cc2)c1,,ClCCl,,,,test
US20060004052A1,Cc1ccc(S(=O)(=O)Nc2ccccc2C(=O)O)cc1.Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O>>Cc1ccc(S(=O)(=O)Nc2ccccc2C(=O)Nc2cc3c4c(c(-c5ccccc5)[nH]c4c2)C=NNC3=O)cc1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040171606A1,CC(C)(C)OC(=O)N1CCc2ccc(C#N)cc2CC1>>N#Cc1ccc2c(c1)CCNCC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090247559A1,C=Cc1ccc(OC(=O)OC(C)(C)C)c(C#N)c1.Cl>>CC(Cl)c1ccc(O)c(C#N)c1,,C1COCCO1,,,,test
US20110060011A1,O=[N+]([O-])c1ccc(-c2nc(-c3ccccc3)c(C(F)(F)F)o2)cc1>>Nc1ccc(-c2nc(-c3ccccc3)c(C(F)(F)F)o2)cc1,[Zn],CC(=O)O,,,,test
US20030216406A1,O=[N+]([O-])c1ccc(S(=O)(=O)NCC(O)CN2CCCCC2)cc1>>Nc1ccc(S(=O)(=O)NCC(O)CN2CCCCC2)cc1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20020040040A1,CCCCCC(O)c1cc(-c2ccccc2C)c(C(=O)N(C)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cn1.CS(=O)(=O)Cl>>CCCCCC(Cl)c1cc(-c2ccccc2C)c(C(=O)N(C)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cn1,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US05610161,Cl.Clc1ccc(C2=CCCNC23CCCCC3)cc1>>Cl.Clc1ccc(C2=CCCNC23CCCCC3)cc1,,CCOCC,ClCCl,,,test
US05422358,BrCCOc1ccccc1.N#CC(c1ccccc1)(c1ccccc1)[C@H]1CCCNC1>>N#CC(c1ccccc1)(c1ccccc1)[C@H]1CCCN(CCOc2ccccc2)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120295884A1,COC(=O)c1ccc(C(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)Oc2ccc3c(C(C)=O)c[nH]c3c2)cc1>>CC(=O)c1c[nH]c2cc(OC(CC(=O)N3C[C@H](F)C[C@H]3C(=O)NCc3cccc(Cl)c3F)c3ccc(C(=O)O)cc3)ccc12,,C1CCOC1,O,[Na+].[OH-],,test
US20090270443A1,CCOCc1nc2c(Cl)nc(C)c(C)c2n1NCCCNS(C)(=O)=O.NCc1ccccc1>>CCOCc1nc2c(NCc3ccccc3)nc(C)c(C)c2n1NCCCNS(C)(=O)=O,,CO,,Cl,c1ccncc1,test
US20110224208A1,COCCN.COc1cccc(N)c1.O=C1Cc2ccccc2C(=O)O1.O=Cc1cccs1>>COCCN1C(=O)c2ccccc2C(C(=O)Nc2cccc(OC)c2)C1c1cccs1,,CCOC(C)=O,ClCCl,,,test
US20060173018A1,COc1cccc(Cl)c1-c1nc(Cl)c2ccccc2n1>>Oc1cccc(Cl)c1-c1nc(Cl)c2ccccc2n1,,ClCCl,,BrB(Br)Br,,test
US20090312383A1,COC(=O)c1ccc(Cl)c2[nH]c(=O)n(C)c12.O=P(Cl)(Cl)Cl>>COC(=O)c1ccc(Cl)c2nc(Cl)n(C)c12,,CCOC(C)=O,,,,test
US20080004273A1,O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.O=C1NCCN1c1ccccn1>>O=C(Cl)N1CCN(c2ccccn2)C1=O,,C1CCOC1,,[Li]CCCC,,test
US05739345,Cn1c(COc2ccc(CC3SC(=O)N(C(c4ccccc4)(c4ccccc4)c4ccccc4)C3=O)cc2)nc2cc(Cl)cnc21>>Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2cc(Cl)cnc21,,O,,CC(=O)O,,test
US06355640B1,CCOC(=O)CBr.O=C1NCCC1n1nc(-c2c(-c3ccccc3)nn3ccccc23)ccc1=O>>CCOC(=O)CN1CCC(n2nc(-c3c(-c4ccccc4)nn4ccccc34)ccc2=O)C1=O,,CN(C)C=O,,O,[H-].[Na+],test
US20120035168A1,Cc1ccc2cc(Cn3cc(C(=O)NCc4c(C)cc(NC(=O)OC(C)(C)C)nc4C)nn3)cnc2c1>>Cc1ccc2cc(Cn3cc(C(=O)NCc4c(C)cc(N)nc4C)nn3)cnc2c1,,CO,ClCCl,O=C(O)C(F)(F)F,,test
US20100216788A1,O=[N+]([O-])c1ccc(Oc2cccc(-c3cnco3)c2)c(Cl)c1>>Nc1ccc(Oc2cccc(-c3cnco3)c2)c(Cl)c1,[Pt],CO,,CCOC(C)=O,,test
US20100081692A1,CI.COC(=O)Cc1ccc(F)cc1OC>>COC(=O)C(C)c1ccc(F)cc1OC,,C1CCOC1,CN1CCCN(C)C1=O,CC(C)[N-]C(C)C.[Li+],,test
US20120214803A1,CC(C)(C)OC(=O)N1CCC(OC(=O)c2ccc3c(c2)-c2cc(Cl)c4cccnc4c2NS3(=O)=O)CC1>>O=C(OC1CCNCC1)c1ccc2c(c1)-c1cc(Cl)c3cccnc3c1NS2(=O)=O,,C1COCCO1,Cl,,,test
US20090137595A1,C/C=C/C(=O)O.Cc1ccc(O)cc1N>>C/C=C/C(=O)Nc1cc(O)ccc1C,CN(C)C=O,CC(=O)N(C)C,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US20140187581A1,CCOC(=O)C1C2C(=O)N(Cc3ccccc3)C(=O)C12>>CCOC(=O)C1C2CN(Cc3ccccc3)CC21,,C1CCOC1,,,,test
US20150368228A1,Cn1ncnc1-c1ccc([N+](=O)[O-])cc1Cl>>Cn1ncnc1-c1ccc(N)cc1Cl,[Fe],O,,CO,[Cl-].[NH4+],test
US04822801,O=C(Cl)C(=O)Cl.O=C(O)c1c(F)c(Cl)c(F)c(F)c1[N+](=O)[O-]>>O=C(Cl)c1c(F)c(Cl)c(F)c(F)c1[N+](=O)[O-],CN(C)C=O,ClCCl,,,,test
US20100298306A1,CCOC(=O)c1nn(C2CCCCO2)c2c1COc1cc(N3CC[C@H](OC)C3)ccc1-2>>CO[C@H]1CCN(c2ccc3c(c2)OCc2c(C(=O)O)nn(C4CCCCO4)c2-3)C1,,CCO,O,[Na+].[OH-],,test
US06537948B1,Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3nsnc3OCc3ccccc3)c(Cl)cc2F)c1=O>>Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3nsnc3O)c(Cl)cc2F)c1=O,,O=C(O)C(F)(F)F,,,,test
US04130658,CCCI.COc1cccc(CCNCCc2ccccc2)c1>>CCCN(CCc1ccccc1)CCc1cccc(OC)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080300275A1,CC(C)(C)OC(=O)CCOCCc1ccc(Br)cc1>>O=C(O)CCOCCc1ccc(Br)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04501746,Fc1ccc(NCc2cccnc2)cc1.O=C=Nc1ccc(Cl)cc1>>O=C(Nc1ccc(Cl)cc1)N(Cc1cccnc1)c1ccc(F)cc1,,CCOC(C)=O,,,,test
US20160176861A1,O=C1CCC(=O)N1Cl.ON=CC1CCC(F)(F)CC1>>ON=C(Cl)C1CCC(F)(F)CC1,,CN(C)C=O,O,,,test
US04420480,CC(=O)OC(C)=O.ON=C1CCc2ccccc2C1>>CC(=O)NC1CCc2ccccc2C1=O,[Pd],,,C1CCOC1,,test
US20050245432A1,C[C@@H](O)[C@@H](C(=O)O)N(C)C(=O)OCc1ccccc1>>CN[C@H](C(=O)O)[C@@H](C)O,[Pd],Cl,,,,test
US20100173955A1,O=C(NCCc1ccc(Cl)cc1)c1ccc(O)cc1.O=Cc1ccc(F)c(C2CC2)c1>>O=Cc1ccc(Oc2ccc(C(=O)NCCc3ccc(Cl)cc3)cc2)c(C2CC2)c1,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20150191480A1,CC(C)(C)OC(=O)N1CCC(CCN2C(=O)c3cc4c(cc3C2(C)C)OCO4)CC1.Cl>>CC1(C)c2cc3c(cc2C(=O)N1CCC1CCNCC1)OCO3.Cl,,CCOC(C)=O,,CCO,,test
US20110183954A1,C1COCCN1.Cn1cnc(Nc2nc(Cl)nc(NC(CNC(=O)OC(C)(C)C)c3ccc(F)cc3)n2)c1>>Cn1cnc(Nc2nc(NC(CNC(=O)OC(C)(C)C)c3ccc(F)cc3)nc(N3CCOCC3)n2)c1,,CC#N,,,,test
US20110250237A1,CC[Si](C#Cc1ccc(C)cc1C)(CC)CC>>C#Cc1ccc(C)cc1C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040147503A1,CCCCI.COC(=O)CC(=O)Nc1ccccc1>>CCCCC(C(=O)Nc1ccccc1)C(=O)OC,,CN1CCCC1=O,,,,test
US20050130900A1,C=CCN1C[C@H](C(=O)N(CCCN(C)C)C(=O)NCC)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21.CC(C)C1NC(=O)C(CCCCN)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(NC(=O)C(N)Cc2ccc3ccccc3c2)CSSCC(C(=O)NC(C(N)=O)C(C)O)NC1=O>>C=CCN1C[C@H](C(=O)N(CCCN(C)C)C(=O)NCC)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21.CC(C)C1NC(=O)C(CCCCN)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(NC(=O)C(N)Cc2ccc3ccccc3c2)CSSCC(C(=O)NC(C(N)=O)C(C)O)NC1=O,,O,,,,test
US20050288321A1,BrC(Br)(Br)Br.COc1ccc(C2=C(c3cn(CCCCO)c4ccccc34)C(=O)NC2=O)c2occc12>>COc1ccc(C2=C(c3cn(CCCCBr)c4ccccc34)C(=O)NC2=O)c2occc12,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070149533A1,CC(C)(C)OC(=O)NCc1cc(NC(=O)C2CCc3ccc(Oc4ccnc5[nH]c(=O)ccc45)cc3C2)cc(C(F)(F)F)c1>>CC(C)(C)OC(=O)NCc1cc(NC(=O)C2CCc3ccc(Oc4ccnc5c4CCC(=O)N5)cc3C2)cc(C(F)(F)F)c1,O=[Pt]=O,CC(=O)O,,,,test
US06177423B1,CN(C)C(=S)Cl.O=C1c2cccc3cc(O)cc(c23)C(=O)N1OCc1ccccc1>>CN(C)C(=S)Oc1cc2c3c(cccc3c1)C(=O)N(OCc1ccccc1)C2=O,,CN(C)C=O,O,[Na+].[OH-],,test
US20070129388A1,CCOC(C)=O.CCOCC.O=C(n1ccnc1)n1ccnc1.OCc1ccccc1>>C=C1CC(C(=O)OCc2ccccc2)C1,,CCOC(C)=O,CCOCC,,,test
US20020049239A1,CC(=O)c1cc([N+](=O)[O-])cc2cc[nH]c12>>CC(=O)c1cc(N)cc2cc[nH]c12,[Pd],CO,,,,test
US04262004,CCCCCCBr.CCOC(=O)C(=CNc1ccc2c(c1)SC1=NCCN12)C(=O)OCC.CN(C)P(=O)(N(C)C)N(C)C>>CCCCCCN(C=C(C(=O)OCC)C(=O)OCC)c1ccc2c(c1)SC1=[N+](CCCCCC)CCN12.[Br-],,CN(C)P(=O)(N(C)C)N(C)C,,[H-].[Na+],,test
US20140155597A1,Cc1ccc(C)c(CC#N)c1.O=[N+]([O-])O>>Cc1cc([N+](=O)[O-])c(C)cc1CC#N,,O,,,,test
US20100104659A1,CNC.Fc1ccc2c(c1)C1=NNC(c3cccc(OCc4ccccc4)c3)C1CO2.O=C(Cl)Cl>>CN(C)C(=O)N1N=C2c3cc(F)ccc3OCC2C1c1cccc(OCc2ccccc2)c1,,C1CCOC1,Cc1ccccc1,CCN(CC)CC,,test
US20120238541A1,CN(C)S(=O)(=O)n1ncc2ccc3c(=O)c(I)c(-c4ccccc4)oc3c21>>O=c1c(I)c(-c2ccccc2)oc2c1ccc1cn[nH]c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080280982A1,COC(=O)c1ccc(C(O)CC(C)C)cc1>>COC(=O)c1ccc(C(=O)CC(C)C)cc1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20100105906A1,O=C(O)c1cccnc1Oc1cc(Cl)ccc1Cl.c1ccc2c(c1)NCCN2C1CC1>>O=C(c1cccnc1Oc1cc(Cl)ccc1Cl)N1CCN(C2CC2)c2ccccc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110178063A1,Cc1cc(C(=O)O)n[nH]1.Nc1cc(-c2cccc3[nH]ccc23)cc2nn(C3CCCCO3)cc12>>Cc1cc(C(=O)Nc2cc(-c3cccc4[nH]ccc34)cc3[nH]ncc23)n[nH]1,,CCN(C(C)C)C(C)C,CN(C)C=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20150094297A1,CC(C)(C)[Si](C)(C)Cl.OCc1ncsc1C(F)(F)F>>CC(C)(C)[Si](C)(C)OCc1ncsc1C(F)(F)F,,ClCCl,,c1c[nH]cn1,,test
US20140213578A1,NCCCN1c2ccccc2CCc2ccccc21.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=S(=O)(NCCCN1c2ccccc2CCc2ccccc21)c1ccc(Cl)cc1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20110312908A1,Cc1c(Cl)ncnc1Cl.Nc1ccc(OC(F)(F)F)cc1>>Cc1c(Cl)ncnc1Nc1ccc(OC(F)(F)F)cc1,,CCO,,CCN(C(C)C)C(C)C,,test
US20150307449A1,CNC(=O)C1(COc2ccc(S(=O)(=O)n3cc(CN(C)C(=O)OC(C)(C)C)cc3-c3ccccc3F)cc2)CC1>>CNCc1cc(-c2ccccc2F)n(S(=O)(=O)c2ccc(OCC3(C(=O)NC)CC3)cc2)c1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20050171087A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.O=C(N[C@@H]1CCCN2c3c(Br)cccc3Oc3ccccc3[C@H]12)C(F)(F)F>>CC(=O)c1cccc2c1N1CCC[C@@H](NC(=O)C(F)(F)F)[C@H]1c1ccccc1O2,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,,Cl,O,test
US20150344437A1,Cn1nc(-c2ccc(OC(F)(F)F)cc2)c(C=O)c1O>>Cc1c(-c2ccc(OC(F)(F)F)cc2)nn(C)c1O,,O,,O=C([O-])O.[Na+],,test
US20110046110A1,Nc1cccc2ccc(-c3cc(F)cc(C(F)(F)F)c3)nc12.O=C(O)c1cnccn1>>O=C(Nc1cccc2ccc(-c3cc(F)cc(C(F)(F)F)c3)nc12)c1cnccn1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110237590A1,CCOC(=O)c1cnc(Cl)cc1N.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1cnc(Cl)cc1NC(=O)C(F)(F)F,,ClCCl,,O,c1ccncc1,test
US20130184241A1,CI.O=[N+]([O-])c1cnc(O)c(I)c1>>COc1ncc([N+](=O)[O-])cc1I,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04362728,BrBr.CNC(=NS(C)(=O)=O)NCCCSc1nccc(NC(N)=NCC(F)(F)F)n1>>CNC(=NS(C)(=O)=O)NCCCSc1ncc(Br)c(NC(N)=NCC(F)(F)F)n1,,ClCCl,,c1ccncc1,,test
US20100273744A1,O=C(O)c1c(Br)cccc1OC(F)(F)F>>OCc1c(Br)cccc1OC(F)(F)F,,C1CCOC1,,CO,,test
US20110178131A1,C=C1Oc2ccc(C#N)cc2N1C1CCN(C(=O)OC(C)(C)C)CC1.Cl>>Cl.N#Cc1ccc2oc(=O)n(C3CCNCC3)c2c1,,ClCCl,,CCOCC,,test
US20060041146A1,CC(=O)c1csc(NC(=O)[C@@H](NC(=O)OC(C)(C)C)[C@@H](C)c2ccccc2)n1>>CC(=O)c1csc(NC(=O)[C@@H](N)[C@@H](C)c2ccccc2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150175648A1,O=C(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@@](F)(Cl)[C@@H]1OC(=O)c1ccccc1)c1ccccc1>>O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@]2(F)Cl)c(=O)[nH]1,,N,,CCO,,test
US20020038055A1,O=Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1,[Ni],Cc1ccccc1,,[H][H],,test
US20060293319A1,CCCN(CCC(C)=O)C(=O)OC(C)(C)C.O=C1Cc2ccc(Cl)cc2N1>>CC(C)(C)OC(=O)N1CCCC(=C2C(=O)Nc3cc(Cl)ccc32)CC1,,CC(C)O,,C1CCNC1,,test
US20010027196A1,CS(=O)(=O)c1nc(N)nc(-c2ccco2)c1C#N.O=C(c1ccccc1)N1CCNCC1>>N#Cc1c(-c2ccco2)nc(N)nc1N1CCN(C(=O)c2ccccc2)CC1,,COCCOC,,,,test
US20130317001A1,CC(C)(C)OC(=O)c1cc(C2CC2)c(OC2CN(C(c3ccccc3)c3ccccc3)C2)cc1F>>O=C(O)c1cc(C2CC2)c(OC2CN(C(c3ccccc3)c3ccccc3)C2)cc1F,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110165202A1,CC(C)CN(C[C@@H](OP(=O)([O-])[O-])[C@H](Cc1ccccc1)NC(=O)OC1CCOC1)S(=O)(=O)c1ccc(N)cc1.[Ca+2]>>CC(C)CN(C[C@@H](OP(=O)([O-])[O-])[C@H](Cc1ccccc1)NC(=O)O[C@H]1CCOC1)S(=O)(=O)c1ccc(N)cc1.[Ca+2],,CO,,,,test
US20040002524A1,COc1ccc(-c2nc3ccccc3n2-c2ccsc2)cc1>>Oc1ccc(-c2nc3ccccc3n2-c2ccsc2)cc1,,ClCCl,,BrB(Br)Br,,test
US20080300242A1,C=CS(C)(=O)=O.CCOc1cc(C2CCNCC2)ccc1NC(=O)C(F)(F)F>>CCOc1cc(C2CCN(CCS(C)(=O)=O)CC2)ccc1NC(=O)C(F)(F)F,CO,ClCCl,,CC(=O)O,O=C([O-])[O-].[K+].[K+],test
US20120028961A1,C[Si](C)(C)N=[N+]=[N-].Cc1nc(CCl)cs1>>Cc1nc(CN=[N+]=[N-])cs1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100179109A1,COC(=O)c1ccc(CN(C)C(=O)OC(C)(C)C)cc1C#N>>CN(Cc1ccc(C(=O)O)c(C#N)c1)C(=O)OC(C)(C)C,,CCO,,[Na+].[OH-],,test
US20060128724A1,C[C@@H](Oc1cccnc1[N+](=O)[O-])c1c(Cl)ccc(F)c1Cl>>C[C@@H](Oc1cccnc1N)c1c(Cl)ccc(F)c1Cl,[Fe],CCO,Cl,,,test
US20160272633A1,N#C[C@H]1CCOC[C@@H]1n1nc(N)c2c(OCc3ccccc3)nccc21>>N#C[C@H]1CCOC[C@@H]1n1nc(N)c2c(=O)[nH]ccc21,[Pd],CCOC(C)=O,CO,,,test
US20110144066A1,CCCCCCCCCCCCc1ccc(S(=O)(=O)Cl)cc1.CCOC(=O)c1nnc(N)s1>>CCCCCCCCCCCCc1ccc(S(=O)(=O)Nc2nnc(C(=O)OCC)s2)cc1,,c1ccncc1,,Cl,,test
US20120232056A1,COC(=O)c1ccc2nc(-c3cc4cc(F)ccc4o3)c(N(C)C3CC3)nc2c1>>CN(c1nc2cc(C(=O)O)ccc2nc1-c1cc2cc(F)ccc2o1)C1CC1,,CO,O,Cl,[Na+].[OH-],test
US20020107251A1,CC(=O)Nc1cccc(-n2c(=O)c(C)nc3cccnc32)c1>>Cc1nc2cccnc2n(-c2cccc(N)c2)c1=O,,Cl,,O=C([O-])O.[Na+],,test
US20070004705A1,CCOC(=O)n1nc(N)c2c1C(C)(C)N(C(=O)OC(C)(C)C)C2.O=C=Nc1cccc(F)c1>>CCOC(=O)n1nc(NC(=O)Nc2cccc(F)c2)c2c1C(C)(C)N(C(=O)OC(C)(C)C)C2,,C1CCOC1,,,,test
US20090227570A1,COc1cccc2c1C(N)CC2.O=[N+]([O-])c1ccc2nc(Cl)ccc2c1>>COc1cccc2c1C(Nc1ccc3cc([N+](=O)[O-])ccc3n1)CC2,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US04382944,CC(CF)(CF)C(=O)C(Br)Oc1ccc(Cl)cc1.c1c[nH]nn1>>CC(CF)(CF)C(=O)C(Oc1ccc(Cl)cc1)n1cnnc1,,ClCCl,,CC#N,,test
US20050043395A1,C=O.COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C(=O)OC(C)(C)C)CC1>>COc1nc(Nc2ccc(Br)cc2F)c2ccc(OCC3CCN(C)CC3)cc2n1,,O=CO,,,,test
US20140371201A1,COc1nc(Cl)c(Cl)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21.FC1(F)CNC1>>COc1nc(N2CC(F)(F)C2)c(Cl)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21,,CS(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20020094963A1,CC(=O)O[C@H]1[C@H](OC(C)=O)[C@@H](OC(C)=O)CO[C@H]1n1c(Br)nc2cc(Cl)c(Cl)cc21>>O[C@@H]1[C@@H](n2c(Br)nc3cc(Cl)c(Cl)cc32)OC[C@H](O)[C@H]1O,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20030044845A1,CNCCc1ccc([N+](=O)[O-])cc1.CS(=O)(=O)Nc1ccc(OCCBr)cc1>>CN(CCOc1ccc(NS(C)(=O)=O)cc1)CCc1ccc([N+](=O)[O-])cc1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20160128326A1,C#CCBr.COC1=C(c2c(Cl)cc(-c3ccc(Cl)cc3)cc2OC)C(=O)CC1>>C#CCC1CC(OC)=C(c2c(Cl)cc(-c3ccc(Cl)cc3)cc2OC)C1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20030220341A1,C=CCCOC(C)=O.O=C(OO)c1cccc(Cl)c1>>CC(=O)OCCC1CO1,,ClCCl,,,,test
US20090023709A1,C1CCOC1.CCN(C(C)C)C(C)C.CCN=C=NCCCN(C)C.ClCCl.O=C(O)c1cnn(-c2ccccc2)c1Cl>>O=C(NC1C2CC3CC(C2)CC1C3)c1cnn(-c2ccccc2)c1Cl,,ClCCl,,Cl,,test
US20110015178A1,O=C(O)c1csc(Br)c1.OB(O)c1ccccc1>>O=C(O)c1csc(-c2ccccc2)c1,,CCO,COCCOC,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070021454A1,C=CC1CC(=O)CCN1Cc1cccc(OC(C)C)c1.N#C[O-].Nc1cccc(F)c1.[C-]#[N+]C1CCCCC1>>C=C[C@H]1C[C@]2(CCN1Cc1cccc(OC(C)C)c1)C(NC1CCCCC1)=NC(=O)N2c1cccc(F)c1,,CO,O,Cl,,test
US20120071478A1,CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)cn1.CN(Cc1ccc(F)c(C(F)(F)F)c1)c1cnc2cc(Br)ccc2n1>>CN(Cc1ccc(F)c(C(F)(F)F)c1)c1cnc2cc(-c3cnn(C(=O)OC(C)(C)C)c3)ccc2n1,,C1COCCO1,CCOC(C)=O,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US04992091,CCOC(=O)c1c(S(=O)(=O)Nc2c(F)cccc2F)nn2c(C)cc(C)nc12>>Cc1cc(C)n2nc(S(=O)(=O)Nc3c(F)cccc3F)cc2n1,,CC(=O)O,,Cl,O,test
US20040259874A1,CCCN1CCOC(c2ccc(O)cc2)C1.O=C1CCC(=O)N1Br>>CCCN1CCOC(c2ccc(O)c(Br)c2)C1,,ClCCl,,,,test
US20070208018A1,CC(=O)Cl.CNc1cc(C(=O)OC)c(N)cc1C(F)(F)F>>COC(=O)c1cc(N(C)C(C)=O)c(C(F)(F)F)cc1N,,C1COCCO1,,,,test
US20100125062A1,CC(=O)N1C=C(OS(=O)(=O)C(F)(F)F)CCC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(=O)N1C=C(B2OC(C)(C)C(C)(C)O2)CCC1,,C1COCCO1,,CC(=O)[O-].[K+],,test
US06376491B1,CCCc1c(C(=O)OCC)oc2cccc(OCCCN(C(=O)OC(C)(C)C)C(C)(C)C)c12>>CCCc1c(C(=O)OCC)oc2cccc(OCCCNC(C)(C)C)c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050026973A1,CCOC(=O)C(C)(C)CCCOc1ccc(OCCCl)cc1.O=C(c1ccccc1)c1ccc2c(c1)S(=O)C=N2>>CCOC(=O)C(C)(C)CCCOc1ccc(OCCn2c(=O)sc3cc(C(=O)c4ccccc4)ccc32)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130029987A1,BrC1C=CCCC1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1C1C=CCCC1,,CN(C)C=O,O,[K],,test
US20030134855A1,CNCCOC.COc1ccc(N2CCOCC2)c2sc(NC(=O)c3ccc(CN(C)C(=O)CCl)cc3)nc12>>COCCN(C)CC(=O)N(C)Cc1ccc(C(=O)Nc2nc3c(OC)ccc(N4CCOCC4)c3s2)cc1,,ClCCl,,O=C([O-])O.[Na+],,test
US06734206B1,COC(=O)COCCCCN1C(=O)CC[C@H]1CCC(O)Cc1cccc(Cl)c1>>O=C(O)COCCCCN1C(=O)CC[C@H]1CCC(O)Cc1cccc(Cl)c1,,C1CCOC1,,Cl,[Li+].[OH-],test
US20160264548A1,C=CC(=O)Cl.NC(=O)c1cc(N2CCC3(CCNC3)C2)cnc1Oc1ccc(Oc2cccc(F)c2)cc1>>C=CC(=O)N1CCC2(CCN(c3cnc(Oc4ccc(Oc5cccc(F)c5)cc4)c(C(N)=O)c3)C2)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20030139433A1,CN(C[C@@H](CCN1CCC(NCCCN)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1.ClC(Cl)Cl.ClCCl.O=C(n1ccnc1)n1ccnc1>>CN(C[C@@H](CCN1CCC(N2CCCNC2=O)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1.Cl.Cl,,ClC(Cl)Cl,ClCCl,,,test
US06110933,CCCCCCCCCCCCC[C@@H](CC(N)=O)OC(=O)[C@H](CCCC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C>>CCCCCCCCCCCCC[C@@H](CC(N)=O)OC(=O)[C@H](CCCC(=O)O)NC(=O)OC(C)(C)C,[Pd],CO,,[H][H],,test
US20040082653A1,COC(=O)c1ccc(COS(C)(=O)=O)c(C)c1.Cc1cc(O)c([N+](=O)[O-])cc1C>>COC(=O)c1ccc(COc2cc(C)c(C)cc2[N+](=O)[O-])c(C)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20110288090A1,CC(C)(C)OC(=O)Nc1ccc(Cl)nc1CO>>CC(C)(C)OC(=O)Nc1ccc(Cl)nc1C=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20160200722A1,CC1(Oc2cc3c(I)n[nH]c3cn2)CC1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CC1(Oc2cc3c(I)nn(C(c4ccccc4)(c4ccccc4)c4ccccc4)c3cn2)CC1,,C1CCOC1,,[H-].[Na+],,test
US20120157437A1,CCO[C@H]1[C@@H](CN=[N+]=[N-])OC(OC)[C@@H]1OS(=O)(=O)C(F)(F)F>>CCO[C@H]1[C@H]2CN[C@@H]1C(OC)O2,[Pd],CCOC(C)=O,,,,test
US20040142921A1,CC(=O)CC(=O)c1cccnc1.COC(=O)[C@@H](N)Cc1ccc(O)cc1>>COC(=O)C(Cc1ccc(O)cc1)NC(C)=CC(=O)c1cccnc1,,CO,,,,test
US04739106,CCOC(=O)C#CCO.O=C(Cl)Cl>>CCOC(=O)C#CCOC(=O)Cl,,c1ccccc1,,,,test
US05527819,CC(=O)OC(C)=O.Nc1cccc(CNC(=O)c2[nH]c3ccc(Cl)cc3c2S(=O)(=O)c2ccccc2)c1>>CC(=O)Nc1cccc(CNC(=O)c2[nH]c3ccc(Cl)cc3c2S(=O)(=O)c2ccccc2)c1,,C1CCOC1,O,,,test
US20110178053A1,CCOC1(O[Si](C)(C)C)CC1.c1cncc(-c2cc3c(cn2)[nH]c2ncc(-c4ccc(N5CCNCC5)cc4)cc23)c1>>c1cncc(-c2cc3c(cn2)[nH]c2ncc(-c4ccc(N5CCN(C6CC6)CC5)cc4)cc23)c1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20060135573A1,COc1cc(NC(=O)c2c(F)cccc2F)cc(OC)c1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COc1cc(NC(=S)c2c(F)cccc2F)cc(OC)c1,,Cc1ccccc1,,,,test
US20070197558A1,Nc1ccc(F)c([N+](=O)[O-])c1.O=C(Cl)c1cccc(C(F)(F)F)c1>>O=C(Nc1ccc(F)c([N+](=O)[O-])c1)c1cccc(C(F)(F)F)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,O,test
US20160083362A1,Fc1cccc(C=C2CN3CCC2CC3)c1>>Fc1cccc(CC2CN3CCC2CC3)c1,[Pd],,,,,test
US20120270879A1,COC(=O)c1cccn2ccnc12.O=C1CCC(=O)N1I>>COC(=O)c1cccn2c(I)cnc12,,CC#N,,,,test
US20100160303A1,CC(C)(C)OC(=O)Nc1ncc(Br)s1.CC(C)O>>CC(C)N(C(=O)OC(C)(C)C)c1ncc(Br)s1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040214798A1,CC(=O)Nc1cc([N+](=O)[O-])ccc1CN1C(=O)c2ccccc2C1=O>>NCc1ccc([N+](=O)[O-])cc1N,,Cl,,,,test
US20030232869A1,COC(=O)c1cc([N+](=O)[O-])c(N)c(F)c1F.Nc1ccccc1Cl>>COC(=O)c1cc([N+](=O)[O-])c(N)c(F)c1Nc1ccccc1Cl,,CCOC(C)=O,,,,test
US20140206663A1,CC(=O)c1ccc2c(c1)NC(=O)CO2.CCOC(=O)C(C)Br>>CCOC(=O)C(C)N1C(=O)COc2ccc(C(C)=O)cc21,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070155805A1,CCOC(=O)c1oc2cc(C(F)(F)F)ccc2c1C>>Cc1c(C(=O)O)oc2cc(C(F)(F)F)ccc12,,CO,,[Na+].[OH-],,test
US20140154178A1,CC1=CC(=C(C#N)C#N)C=C(C)O1.COc1cc(C=O)ccc1NC(=O)OC(C)(C)C>>COc1cc(/C=C/C2=CC(=C(C#N)C#N)C=C(C)O2)ccc1N,,CCO,,C1CCNCC1,,test
US20100063038A1,COC[C@@H]1CCCN1.Nc1ncnn2c(CCCBr)cc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)c(F)c3)c12>>COC[C@@H]1CCCN1CCCc1cc(-c2ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)c(F)c2)c2c(N)ncnn12,,CN(C)C=O,,CCN(CC)CC,,test
US03988448,C1CO1.c1ccc(C2(c3ccccc3)CCNCCO2)cc1>>OCCN1CCOC(c2ccccc2)(c2ccccc2)CC1,,CO,,O,,test
US20100297079A1,C[C@@]1(O)C(O)C(CO)O[C@H]1n1cc(I)c2c(N)ncnc21.O=C(O)c1ccc(B(O)O)s1>>C[C@@]1(O)C(O)C(CO)O[C@H]1n1cc(-c2ccc(C(=O)O)s2)c2c(N)ncnc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,CC(=O)[O-].[K+],,test
US20080274892A1,CC1(C)SC(=O)N(Cc2ccccc2[N+](=O)[O-])C1O>>CC1(C)CN(Cc2ccccc2[N+](=O)[O-])C(=O)S1,,ClC(Cl)Cl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20090240052A1,CC(=O)c1ccc(B(O)O)cc1.COC(=O)C1(Br)C=CC=CC1NC(=O)c1ccccc1>>CC(=O)c1ccc(-c2ccc(C(=O)O)c(NC(=O)c3ccccc3)c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,O,Cc1ccccc1,O=C([O-])O.[Na+],test
US20080319188A1,C1CCOC1.CCN(CC)CC.Nc1cc(Oc2cc(F)c(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ccn1.O=C(Cl)Oc1ccccc1>>O=C(Nc1cc(Oc2cc(F)c(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ccn1)N1CC(O)C1,,C1CCOC1,CCOC(C)=O,O=C([O-])O.[Na+],,test
US20150011551A1,COc1ccc(-c2cncc(N)c2)cc1.O=S(=O)(Cl)c1cc(Cl)ccc1OC(F)(F)F>>COc1ccc(-c2cncc(NS(=O)(=O)c3cc(Cl)ccc3OC(F)(F)F)c2)cc1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20080293701A1,CCCCCNC(=S)NC[C@H](O)[C@H](C[C@H](Cc1ccc(OC)c(OCCCOC)c1)C(C)C)NC(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CCCCCNC(=S)NC[C@H](O)[C@@H](N)C[C@H](Cc1ccc(OC)c(OCCCOC)c1)C(C)C.O=C([O-])C(F)(F)F,,ClCCl,,,,test
US20030199550A1,CN(CC[C@@H]1CC[C@@H](CCCO)CC1)C(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CN(CC[C@@H]1CC[C@@H](CCCOS(C)(=O)=O)CC1)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US04250183,CC(c1ccccc1)N(CCCC(=O)O)C(=O)c1ccc(Cl)cc1.CCOC(=O)CCCNCc1ccccc1>>CC(c1ccccc1)N(CCCC(=O)N(CCCC(=O)O)Cc1ccccc1)C(=O)c1ccc(Cl)cc1,,CCO,,[K+].[OH-],,test
US04892872,CC1Oc2c(C(=O)NC3CCN(Cc4ccccc4)CC3)cc(Cl)cc2N(C)C1=O.O=C(OO)c1cccc(Cl)c1>>CC1Oc2c(C(=O)[NH+]([O-])C3CCN(Cc4ccccc4)CC3)cc(Cl)cc2N(C)C1=O,,ClC(Cl)Cl,,,,test
US20150336962A1,CSc1ccc(C=O)cc1.NCCn1cc(NC(=O)c2cnn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1>>CSc1ccc(CNCCn2cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n2)cc1,,CO,,[BH3-]C#N.[Na+],,test
US20100081643A1,COC(=O)c1cc(Oc2nc3cc(-c4ccc(Br)cc4)c(Cl)cc3[nH]2)ccc1C.OB(O)c1cccc(F)c1>>COC(=O)c1cc(Oc2nc3cc(-c4ccc(-c5cccc(F)c5)cc4)c(Cl)cc3[nH]2)ccc1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20140356322A1,CC(C)(C)OC(=O)CBr.COCOc1ccc2c(c1)C[C@@H](CCCCOCCOCCOCCOCCO)[C@H]1[C@@H]3CC[C@H](OCOC)[C@@]3(C)CC[C@H]21>>COCOc1ccc2c(c1)C[C@@H](CCCCOCCOCCOCCOCCOCC(=O)OC(C)(C)C)[C@H]1[C@@H]3CC[C@H](OCOC)[C@@]3(C)CC[C@H]21,,CN(C)C=O,,[H-].[Na+],,test
US20070244131A1,OCC(O)c1nc(Cl)cc(NCCc2ccc(Cl)cc2Cl)n1>>O=Cc1nc(Cl)cc(NCCc2ccc(Cl)cc2Cl)n1,,CO,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20030004340A1,BrCCCc1ccccc1.CC1(c2cccc(-c3nc[nH]n3)c2)CCNCC1.CN(C)C=O>>CC1(c2cccc(-c3nc[nH]n3)c2)CCN(CCCc2ccccc2)CC1.N,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20110046153A1,CCCNC1CCc2ncsc2C1.O=CCCCC(=O)NC1Cc2ccccc2C1>>CCCN(CCCCC(=O)NC1Cc2ccccc2C1)C1CCc2ncsc2C1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20080153810A1,O=[N+]([O-])O.O=[N+]([O-])c1ccc2[nH]ncc2c1>>O=[N+]([O-])c1ccc2nn([N+](=O)[O-])cc2c1,,CC(=O)O,,CC(=O)OC(C)=O,,test
US04203909,C#CCN.CNCc1ccc(CSCCNC(=C[N+](=O)[O-])SC)o1>>C#CCNC(=C[N+](=O)[O-])NCCSCc1ccc(CNC)o1,,CC#N,,,,test
US20030236276A1,CC(C)N=C=O.CCOC(=O)c1c(-c2ccc3c(c2)CCN3)c(C)n2c1-c1cc(OC)c(OC)cc1CC2>>CCOC(=O)c1c(-c2ccc3c(c2)CCN3C(=O)NC(C)C)c(C)n2c1-c1cc(OC)c(OC)cc1CC2,,ClCCl,,,,test
US20050192302A1,CC(=O)OCc1cc(C(F)(F)F)ccn1>>OCc1cc(C(F)(F)F)ccn1,,CO,O,[Na+].[OH-],,test
US20060276465A1,COc1ccc(F)cc1C1CCN(C(=O)OC(C)(C)C)CC1>>Oc1ccc(F)cc1C1CCNCC1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20150368246A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc(N)c(-c4cc5c(F)cccc5[nH]4)n3)cc12.COC(=O)CC(OC)OC>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3C(CC(=O)OC)N4)cc12,,C1COCCO1,,CCN(CC)CC,Cl,test
US20040171634A1,C[Si](C)(C)CCOC(=O)Oc1ccc([N+](=O)[O-])cc1.Cc1cc(F)c(N)cc1N>>Cc1cc(F)c(N)cc1NC(=O)OCC[Si](C)(C)C,CN(C)c1ccncc1,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20130085144A1,CC(C)(C)OC(=O)c1ccc(-c2ccncc2)cc1[N+](=O)[O-].CI>>C[n+]1ccc(-c2ccc(C(=O)OC(C)(C)C)c([N+](=O)[O-])c2)cc1.[I-],,CC(C)=O,,,,test
US20060014816A1,O=Cc1ccc2c(c1)-c1[nH]nc(I)c1C2.OB(O)c1ccsc1>>O=Cc1ccc2c(c1)-c1[nH]nc(-c3ccsc3)c1C2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])O.[Na+],,test
US20060264432A1,N#Cc1c(N)nc(S)c(C#N)c1-c1cc(Cl)c(O)c(Cl)c1.NC(=O)CBr>>N#Cc1c(N)nc(CC(N)=O)c(C#N)c1-c1cc(Cl)c(O)c(Cl)c1,,CN(C)C=O,O,O=C([O-])O.[Na+],,test
US20060052597A1,CC(C)(C)OC(=O)N1CCNCC1.O=C(Cl)c1ccc(OCCCN2CCCCC2)cc1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(OCCCN3CCCCC3)cc2)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20060079572A1,CCOC(C)OC1CCC(C)(OC(C)OCC)C(Oc2ccc([N+](=O)[O-])cc2)C=CC(C)C(/C(C)=C/C=C/C(C)CC2OC2C(C)C(CC)OC(C)OCC)OC(=O)C1C(=O)O.N>>CCOC(C)OC1CCC(C)(OC(C)OCC)C(OC(N)=O)C=CC(C)C(/C(C)=C/C=C/C(C)CC2OC2C(C)C(CC)OC(C)OCC)OC(=O)C1,,C1CCOC1,,CCOC(C)=O,O,test
US20130237525A1,BrC(Br)(Br)Br.OCc1ccc(Oc2ccccc2)nc1>>BrCc1ccc(Oc2ccccc2)nc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150018343A1,Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccccc1CN1CCCC(NC(=O)OC(C)(C)C)C1)C3>>Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccccc1CN1CCCC(N)C1)C3,,O,,C1COCCO1,Cl,test
US20060079533A1,O=C(Nc1ccccn1)OCCOc1ccc(C2CCN(C(=O)OCC(Cl)(Cl)Cl)CC2OCc2ccc3ccccc3c2)cc1>>O=C(Nc1ccccn1)OCCOc1ccc(C2CCNCC2OCc2ccc3ccccc3c2)cc1,[Zn],CC(=O)O,,,,test
US05539112,CC(C)(C)C(=O)Nc1ccc(-c2cc(=O)c3c(NCCCn4ccnc4)c(F)cc(F)c3o2)cc1F>>Nc1ccc(-c2cc(=O)c3c(NCCCn4ccnc4)c(F)cc(F)c3o2)cc1F,,O=S(=O)(O)O,,,,test
US20120316147A1,Cc1nc(C(N)CC(C)C)no1.O=C(O)c1ccc(C2CC2)c(OCC2CC2)n1>>Cc1nc(C(CC(C)C)NC(=O)c2ccc(C3CC3)c(OCC3CC3)n2)no1,,CCCCCCC,,CO,,test
US20150166527A1,Cc1cccc2nc([C@@H]3[C@@H](C)CCN3C(=O)OC(C)(C)C)[nH]c12.Cl>>Cc1cccc2nc([C@H]3NCC[C@@H]3C)[nH]c12.Cl,,CO,,C1COCCO1,,test
US20070129416A1,COc1ccc(C2=NC(C)(c3ccc(Cl)cc3)C(C)(c3ccc(Cl)cc3)N2)c(OC(C)C)c1.O=C(Cl)Cl>>COc1ccc(C2=NC(C)(c3ccc(Cl)cc3)C(C)(c3ccc(Cl)cc3)N2C(=O)Cl)c(OC(C)C)c1,,CCN(CC)CC,,,,test
US20150284408A1,Cc1ccc(CNC2CCN(C(=O)OC(C)(C)C)CC2)cc1C(C)C(F)(F)F>>Cc1ccc(CNC2CCNCC2)cc1C(C)C(F)(F)F,,C1COCCO1,ClCCl,Cl,,test
US20060135488A1,CCOC(=O)COc1c(C(=O)OC)sc2c1sc1cc(C(=O)O)ccc12.NC1CCCCC1>>CCOC(=O)COc1c(C(=O)OC)sc2c1sc1cc(C(=O)NC3CCCCC3)ccc12,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US05554706,C=CCOc1ccc(C(=O)O)cc1.N#Cc1ccc(O)cc1>>C=CCOc1ccc(C(=O)Oc2ccc(C#N)cc2)cc1,,ClC(Cl)Cl,,O,,test
US20080161366A1,COc1ccccc1N.O=[N+]([O-])c1ccccc1F>>COc1ccccc1Nc1ccccc1[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],,test
US20120122846A1,CS(=O)(=O)OS(C)(=O)=O.OCC1(F)CCN(Cc2ccccc2)CC1>>CS(=O)(=O)OCC1(F)CCN(Cc2ccccc2)CC1,CN(C)c1ccncc1,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20090298816A1,CC(C)N.Cc1cc2cn[nH]c2c2c(=O)oc(-c3cc(C(F)F)nn3-c3ncccc3Cl)nc12>>Cc1cc2cn[nH]c2c(C(=O)NC(C)C)c1NC(=O)c1cc(C(F)F)nn1-c1ncccc1Cl,,CC#N,O,,,test
US20080214598A1,CN(CCc1ccc(Cl)c(C(C)(C)O[SiH2]C(C)(C)C)c1)C(=O)OC(C)(C)C>>CN(CCc1ccc(Cl)c(CO)c1)C(=O)OC(C)(C)C,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20140213586A1,CO.COc1cc([N+](=O)[O-])cnc1Cl>>COc1cc([N+](=O)[O-])cnc1OC,,CO,,C[O-].[Na+],,test
US04411839,C=O.N#Cc1cn(Nc2c(Cl)cc(Cl)cc2Cl)c(=O)[nH]c1=O>>N#Cc1cn(N(CO)c2c(Cl)cc(Cl)cc2Cl)c(=O)[nH]c1=O,,O=CO,,O,,test
US20060116383A1,CCOC(=O)CC(c1ccccc1)n1cnc2cc(NC(=O)c3ccc(NC(=N)N)cc3)ccc21>>N=C(N)Nc1ccc(C(=O)Nc2ccc3c(c2)ncn3C(CC(=O)O)c2ccccc2)cc1,,Cl,,,,test
US20120157487A1,O=S(Cl)Cl.OCc1cccnc1F>>Fc1ncccc1CCl,,ClCCl,,,,test
US04301159,CCN(CC)CCNC(=O)c1cc(NS(C)(=O)=O)ccc1OC.COS(=O)(=O)OC>>CCN(CC)CCNC(=O)c1cc(N(C)S(C)(=O)=O)ccc1OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110118248A1,CC(=O)c1cc(S(=O)(=O)Nc2cc(Cl)cnc2Br)ccc1Cl.C[Mg]Br>>CC(C)(O)c1cc(S(=O)(=O)Nc2cc(Cl)cnc2Br)ccc1Cl,,C1CCOC1,CCOCC,,,test
US20120329649A1,CC(=O)c1cc(Cl)cc(Cl)c1.O=Cc1ccc(-n2cncn2)cc1>>O=C(/C=C/c1ccc(-n2cncn2)cc1)c1cc(Cl)cc(Cl)c1,,CCO,O,[Na+].[OH-],,test
US20130018052A1,CC(=O)N1CCn2c1nc(-c1cccc(C)n1)c2-c1ccc2ncc(-n3cccn3)nc2c1.CN(C)CCO>>Cc1cccc(-c2nc3n(c2-c2ccc4ncc(OCCN(C)C)nc4c2)CCN3)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05449686,COc1ccc(C2(C#N)CCC(=O)CC2)cc1OC1CCCC1.NO>>COc1ccc(C2(C#N)CCC(=NO)CC2)cc1OC1CCCC1,,c1ccncc1,,Cl,,test
US06642395B1,CO.O=C(O)[C@H](O)c1ccc(Cl)cc1>>COC(=O)[C@H](O)c1ccc(Cl)cc1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US06194447B1,Cl.N#CNc1ccccc1.Nc1ccc(-n2c(N)nc3ccccc32)cc1>>Cl.N=C(Nc1ccccc1)Nc1ccc(-n2c(N)nc3ccccc32)cc1,,CC#N,,,,test
US06417183B1,CC(C)C(=O)O.c1ccc2c(c1)CCCC2N1CCCNCC1>>CC(C)CN1CCCN(C2CCCc3ccccc32)CC1,,O,,[Na+].[OH-],,test
US20050124577A1,CC(C)(C)OC(=O)N[C@@H](COCc1ccccc1)C(=O)ON1C(=O)CCC1=O>>CC(C)(C)OC(=O)N[C@H](CO)COCc1ccccc1,,C1CCOC1,,O,[BH4-].[Na+],test
US20130266645A1,COc1ccc2c(c1)CC[C@H]1[C@@H]3C[C@H](N=[N+]=[N-])[C@H](O)[C@@]3(C)CC[C@H]21>>COc1ccc2c(c1)CC[C@H]1[C@@H]3C[C@H](N)[C@H](O)[C@@]3(C)CC[C@H]21,[Ni],CO,,NN,O,test
US20140228303A1,Br.CC(=O)Oc1ccc(Cc2cc([C@@H]3OC(OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)ccc2Cl)cc1>>CC(=O)O[C@H]1[C@H](c2ccc(Cl)c(Cc3ccc(O)cc3)c2)OC(Br)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,CC(=O)O,ClCCl,O,,test
US05461049,CCCCCCCCCCCCn1nnc(C(=NOC)C(=O)OCC)n1>>CCCCCCCCCCCCn1nnc(C(=NOC)C(=O)O)n1,,CCO,,[Na+].[OH-],,test
US20060276475A1,Cc1noc(C)c1CCl.Nc1nc(N2CCNCC2)nc2nc(-c3ccco3)nn12>>Cc1noc(C)c1CN1CCN(c2nc(N)n3nc(-c4ccco4)nc3n2)CC1,,CC#N,,CCN(CC)CC,,test
US04005103,CC(=O)Cl.CC1NC(C2CC2)CC1c1cccc(C(F)(F)F)c1>>CC(=O)N1C(C)C(c2cccc(C(F)(F)F)c2)CC1C1CC1,,c1ccccc1,,CCN(CC)CC,,test
US20110071197A1,Fc1ccc(Nc2ccc(OCc3ccccc3)cc2)cc1>>Oc1ccc(Nc2ccc(F)cc2)cc1,[Pd],CCO,,CCOC(C)=O,,test
US20150011552A1,N#Cc1ccccc1-c1ccc(COCc2ccc(Cl)nc2)cc1.NN>>N#Cc1ccccc1-c1ccc(COCc2ccc(NN)nc2)cc1,,CCO,,O,,test
US20110263544A1,CCOC(=O)c1cc(CCOCc2ccccc2)n(-c2ccc(F)cc2C(F)(F)F)c1C.CS(=O)(=O)c1ccc(N)cc1>>Cc1c(C(=O)Nc2ccc(S(C)(=O)=O)cc2)cc(CCOCc2ccccc2)n1-c1ccc(F)cc1C(F)(F)F,,Cc1ccccc1,,C[Al](C)C,,test
US20120294835A1,Cl.Clc1cc(Cl)ncn1.Nc1ccccc1>>Cl.Clc1cc(Nc2ccccc2)ncn1,,CC(C)O,,,,test
US20060074087A1,CCOC(=O)c1cc2c(nc1Cl)CCN(Cc1ccccc1)C2.Cl>>CCOC(=O)c1cc2c(nc1Cl)CCNC2.Cl,,CO,ClCCl,CC(Cl)OC(=O)Cl,,test
US05635510,CC(C)Oc1cccc(C(=O)N2CCC(CCBr)(c3ccc(C(F)(F)F)cc3)C2)c1.NC(=O)C1(c2ccccc2)CCNCC1>>CC(C)Oc1cccc(C(=O)N2CCC(CCN3CCC(C(N)=O)(c4ccccc4)CC3)(c3ccc(C(F)(F)F)cc3)C2)c1,,C1CCOC1,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20080146607A1,CCCC1(C(=O)c2ccc3c(ccn3C(=O)OC(C)(C)C)c2)CCCN1C(=O)OC(C)(C)C>>CCCC1(C(=O)c2ccc3[nH]ccc3c2)CCCN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05462941,C[C@@H](N)c1ccccc1.Clc1nnc(-c2cccs2)c2sccc12>>C[C@@H](Nc1nnc(-c2cccs2)c2sccc12)c1ccccc1,,CN1CCCC1=O,,[K+].[OH-],,test
US20070015802A1,COc1cc(OC)c2c(=O)cc(-c3ccc([N+](=O)[O-])cc3Br)oc2c1[C@@H]1CCN(C)[C@H]1CO>>COc1cc(OC)c2c(=O)cc(-c3ccc(N)cc3Br)oc2c1[C@@H]1CCN(C)[C@H]1CO,[Fe],CC(=O)O,O,O=C([O-])[O-].[Na+].[Na+],,test
US06172228B2,Fc1ccc(C(c2ccc(F)cc2)N2CCNCC2)cc1.O=S(=O)(CCCCCCl)NCCCCO>>O=S(=O)(CCCCCN1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)NCCCCO,,CCN(C(C)C)C(C)C,,,,test
US20090324581A1,C=C(C)OB(O)O.COC(=O)c1ccc(C(F)(F)F)c(OS(=O)(=O)C(F)(F)F)c1>>C=C(C)c1cc(C(=O)OC)ccc1C(F)(F)F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110319378A1,CC[C@@H](C=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1.C[Mg]Cl>>CC[C@@H]([C@@H](C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1,,C1CCOC1,C1CCOC1,,,test
US20110245224A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.C[C@H]1CN(c2c(CO)ccc(F)c2F)C[C@@H](C)O1>>C[C@H]1CN(c2c(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)ccc(F)c2F)C[C@@H](C)O1,,ClCCl,,c1c[nH]cn1,,test
US04803211,CCCc1c(CSc2nnc(S)s2)ccc(C(C)=O)c1O.CCOC(=O)c1ccc(CBr)cc1>>CCCc1c(CSc2nnc(SCc3ccc(C(=O)OCC)cc3)s2)ccc(C(C)=O)c1O,,Cc1ccccc1,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140256782A1,CC1(C)C=CC(=O)CC1.[Li]C>>CC1(C)C=CC(C)(O)CC1,,CCOCC,,,,test
US20100239526A1,COc1ccc(Cn2nccc2N)cc1.CSc1ncc2c(n1)CC/C(=C\N(C)C)C2=O>>COc1ccc(Cn2ncc3c4c(cnc32)CCc2nc(SC)ncc2-4)cc1,,CC(C)O,CO,O=C(O)C(F)(F)F,,test
US20140057899A1,CS(=O)CC[C@@H](CCO)NC(=O)OC(C)(C)C>>C=C[C@@H](CCO)NC(=O)OC(C)(C)C,,Clc1ccccc1Cl,,CC(=O)[O-].[Na+],,test
US20080221063A1,COC(=O)[C@H]1CN(S(=O)(=O)c2ccc3c(Cl)cn(S(=O)(=O)c4ccccc4)c3c2)CC(=O)N1CC1CCN(c2ccc(=O)n(C)n2)CC1>>COC(=O)[C@H]1CN(S(=O)(=O)c2ccc3c(Cl)c[nH]c3c2)CC(=O)N1CC1CCN(c2ccc(=O)n(C)n2)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140206663A1,CCOC(=O)C(C)N1C(=S)COc2ccc(OC3CN(C(=O)OC(C)(C)C)C3)cc21.NN>>CC1C(=O)NN=C2COc3ccc(OC4CN(C(=O)OC(C)(C)C)C4)cc3N21,,CCO,,O,,test
US20050130954A1,CC(C)(C)OC(=O)N1CCNCC1.Clc1ncnc2ccc(Br)cc12>>CC(C)(C)OC(=O)N1CCN(c2ncnc3ccc(Br)cc23)CC1,,CCOC(C)=O,CN1CCCC1=O,CCN(CC)CC,,test
US20080096885A1,C1CCNC1.COC(=O)N(NC(=O)c1c(C)c(Br)nc2ccccc12)c1ccccc1>>COC(=O)N(NC(=O)c1c(C)c(N2CCCC2)nc2ccccc12)c1ccccc1,,CC(=O)N(C)C,,,,test
US05952362,CS(=O)(=O)Cl.Nc1cc([N+](=O)[O-])ccc1Br>>CS(=O)(=O)Nc1cc([N+](=O)[O-])ccc1Br,,ClCCl,,CCN(CC)CC,Cl,test
US20070167413A1,CC(C)(C)c1cc(N)n(-c2nc(C(F)(F)F)nc(-c3ccccc3)c2-c2ccccc2)n1.O=C=Nc1c(Cl)cccc1Cl>>CC(C)(C)c1cc(NC(=O)Nc2c(Cl)cccc2Cl)n(-c2nc(C(F)(F)F)nc(-c3ccccc3)c2-c2ccccc2)n1,,ClCCl,,CCN(CC)CC,O,test
US20150166480A1,CC(C)(C)OC(=O)N1CCC(COc2ccc(Cl)nn2)CC1>>Clc1ccc(OCC2CCNCC2)nn1,,CO,,C1COCCO1,Cl,test
US20140213592A1,CCO.O=C(O)c1cc(Cl)nnc1Cl>>CCOC(=O)c1cc(Cl)nnc1Cl,,O=S(Cl)Cl,,ClCCl,,test
US20150210630A1,NO.O=C(CN1C(=O)c2ccccc2C1=O)c1ncc(Cl)cc1Cl>>O=C1c2ccccc2C(=O)N1CC(=NO)c1ncc(Cl)cc1Cl,,CCO,,Cl,,test
US20100292184A1,C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C#N)[C@H]3C[C@H]3[C@@H]12.NO>>C[C@]12CCC(=NO)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C#N)[C@H]3C[C@H]3[C@@H]12,,c1ccncc1,,Cl,,test
US06291455B1,CCOCCO.COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1O.ClCCl>>CCOCCOc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OC.Cl,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040204397A1,Nc1ccccc1CCNC1CCN(Cc2ccccc2)CC1.O=C(c1ncc[nH]1)c1ncc[nH]1>>O=C1Nc2ccccc2CCN1C1CCN(Cc2ccccc2)CC1,,C1CCOC1,,,,test
US20100016311A1,Cn1cc(NC(=O)c2cc([N+](=O)[O-])cn2C)cc1C(=O)NCCN1CCOCC1>>Cn1cc(NC(=O)c2cc(N)cn2C)cc1C(=O)NCCN1CCOCC1,[Pd],CO,,,,test
US20120283241A1,COc1ccc(CN(c2cc(Cl)nn3c(C#N)cnc23)C2CC2)cc1.COc1ccc(CNc2cccc(C(=O)OC(C)(C)C)c2)cc1>>COc1ccc(CN(c2cccc(C(=O)OC(C)(C)C)c2)c2cc(Cl)nn3c(C#N)cnc23)cc1,,CO,,,,test
US06096907,CC(=O)O.CC(C)=CCC/C(C)=C/CC/C(C)=C/CC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1>>CC(=O)[O-].CC(C)=CCC/C(C)=C/CC/C(C)=C/CC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1,,CCCCCCC,CCOC(C)=O,CC(=O)OC(C)=O,,test
US20070293516A1,CC(C)n1nc(I)c2c(N)ncnc21.OB(O)c1cncnc1>>CC(C)n1nc(-c2cncnc2)c2c(N)ncnc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US20150133432A1,CCC1(C)CNC(C)(C)CN1C(=O)OC(C)(C)C.Cc1nn(C2CCCCO2)c2nc(Br)cc(COS(C)(=O)=O)c12>>CCC1(C)CN(Cc2cc(Br)nc3c2c(C)nn3C2CCCCO2)C(C)(C)CN1C(=O)OC(C)(C)C,,C1CCOC1,O,CCN(C(C)C)C(C)C,[I-].[K+],test
US20100168418A1,CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCNCC1.O=CCn1c(=O)cc(OCc2ccccc2)c2ccccc21>>CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)cc(OCc3ccccc3)c3ccccc32)CC1,,CC(=O)O,ClCCl,O=C([O-])O.[Na+],,test
US05166170,COc1ccc(N)c(C(C)=NNc2ccccc2)c1>>COc1ccc(N)c(-c2cc3ccccc3[nH]2)c1,,O,,[NH4+].[OH-],,test
US20080306096A1,CC(C)(C#N)c1cc(C(=O)O)ccn1.COc1ccc2c(Nc3cc(N)ccc3C)ncnc2c1>>COc1ccc2c(Nc3cc(NC(=O)c4ccnc(C(C)(C)C#N)c4)ccc3C)ncnc2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06124281,CCCNCCC.CCOC(=O)c1n[nH]c2c(=O)[nH]c3cc(Cl)ccc3c(=O)c12>>CCCN(CCC)C(=O)c1n[nH]c2c(=O)[nH]c3cc(Cl)ccc3c(=O)c12,,Cc1ccccc1,,C[Al](C)C,,test
US20110237564A1,CN(CCOCCF)C(=O)OC(C)(C)C.Cl>>CNCCOCCF.Cl,,C1COCCO1,,,,test
US04714492,CCOC(=O)c1c(-c2ccccc2)oc(-c2ccccc2)cc1=O.CN>>CCOC(=O)c1c(-c2ccccc2)n(C)c(-c2ccccc2)cc1=O,,CO,O,CC(=O)O,,test
US20060079533A1,CC(C)(C)OC(=O)N1CCC(c2ncc(OCc3ccccc3)cn2)C(O)C1>>CC(C)(C)OC(=O)N1CCC(c2ncc(O)cn2)C(O)C1,[Pd],CO,,,,test
US20110195948A1,CC(C)(C)OC(=O)N1CCC(C)(C(=O)O)CC1.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12>>CC(C)(C)OC(=O)N1CCC(C)(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4Cl)nc23)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130143870A1,N=CN.O=C(C1=C(Cl)CCN(Cc2ccccc2)CC1)c1ccccc1>>c1ccc(CN2CCc3ncnc(-c4ccccc4)c3CC2)cc1,,CCO,,Cl,[Na],test
US20130090386A1,CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(-c2cccc(Cl)c2)cc1.Cl>>Cl.N[C@@H]1C[C@H]1c1ccc(-c2cccc(Cl)c2)cc1,,CCOCC,,,,test
US20050192302A1,N[C@H]1CCN(C(=O)C2CCN(c3cccc(C(F)(F)F)n3)CC2)C1.O=C1CCC(O)(c2ccc(-c3ncccn3)cn2)CC1>>O=C(C1CCN(c2cccc(C(F)(F)F)n2)CC1)N1CC[C@H](NC2CCC(O)(c3ccc(-c4ncccn4)cn3)CC2)C1,,ClCCl,,CCN(CC)CC,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20150080393A1,CCOC(C)=O.Cc1ccn(-c2cc(Cl)ccc2[C@@H](Oc2cc(N3CCC4(CC3)C[C@@H](C(=O)O)N(C(=O)OCc3ccccc3)C4)nc(N)n2)C(F)(F)F)n1.O=C(Cl)C1CCC1>>CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4ccc(Cl)cc4-n4ccc(C)n4)C(F)(F)F)nc(NC(=O)C4CCC4)n3)CC2)CN1C(=O)OCc1ccccc1,,CCOC(C)=O,,c1ccncc1,,test
US20010051731A1,Nc1nccs1.O=C(Nc1ccc(C(CC2CCCC2)C(=O)O)cc1)c1ccccc1>>O=C(Nc1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1)c1ccccc1,,ClCCl,O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20110053916A1,Brc1cnc(-c2ccccc2)nc1Br.Nc1cc(C2CC2)n[nH]1>>Brc1cnc(-c2ccccc2)nc1Nc1cc(C2CC2)[nH]n1,,CCCCO,,,,test
US06043367,COC(=O)[C@H]1O[C@](O)(c2ccc(C)cc2[N+](=O)[O-])[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.O=C1CCC(=O)N1Br>>COC(=O)[C@H]1O[C@](O)(C2=C([N+](=O)[O-])CC(=CBr)C=C2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20090062274A1,Cc1cc(NCc2ccccc2)nc(N)n1.II>>Cc1nc(N)nc(NCc2ccccc2)c1I,,CO,,,,test
US04857644,Clc1cccc(N2CCNCC2)c1.O=S(=O)(Cl)c1ccc2c(c1)Cc1ccccc1-2>>Cl.O=S(=O)(c1ccc2c(c1)Cc1ccccc1-2)N1CCN(c2cccc(Cl)c2)CC1,,ClCCl,,CCN(CC)CC,,test
US20160115158A1,COc1nc(Cl)ccc1N.O=S(=O)(Cl)Cc1cnc(Cl)c(Cl)c1>>O=S(=O)(Cc1cnc(Cl)c(Cl)c1)Nc1ccc(Cl)nc1O,,CCO,,[Na+].[OH-],,test
US20040106667A1,CC(C)(C)OC(=O)N(c1ccc2c(c1)c(I)nn2C(=O)OC(C)(C)C)S(=O)(=O)c1ccccc1S(C)(=O)=O.CN(C)C=O.c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CS(=O)(=O)c1ccccc1S(=O)(=O)Nc1ccc2[nH]nc(-c3ccc4[nH]ccc4c3)c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O=C([O-])O,[Na+],,,test
US20110201599A1,Nc1nccc(-c2cn(S(=O)(=O)c3ccccc3)c3nccc(N4CC[C@H](NCCC(F)(F)F)C4)c23)n1>>Nc1nccc(-c2c[nH]c3nccc(N4CC[C@H](NCCC(F)(F)F)C4)c23)n1,,CO,,[Li+].[OH-],,test
US20110201650A1,C#CC1(O)CCCCC1.Cc1ccc(C=O)cc1>>Cc1ccc(C(O)C#CC2(O)CCCCC2)cc1,,C1CCOC1,,[Li]CCCC,,test
US20130178478A1,CCCc1nc(N)ccc1OC.CCOC(=O)c1nnc(Cl)cc1Cl>>CCCc1nc(Nc2cc(Cl)nnc2C(=O)OCC)ccc1OC,,CC#N,,,,test
US05294612,CCc1[nH]n(C2CCCC2)c2nc(-c3ccnc4ccccc34)nc(=O)c1-2>>CCc1[nH]n(C2CCCC2)c2nc(C3CCNC4CCCCC43)nc(=O)c1-2,O=[Pt],CC(=O)O,,,,test
US20040010009A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc([N+](=O)[O-])cc2Cl)CC1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(N)cc2Cl)CC1,[Zn],CC(=O)O,,,,test
US20120190675A1,C[C@@H](c1ccc(Br)cc1)N1CCC2(CCC3(CC2)OCC(C)(C)CO3)OC1=O>>C[C@@H](c1ccc(Br)cc1)N1CCC2(CCC(=O)CC2)OC1=O,,CC(C)=O,,Cl,,test
US04952583,CC(C)(C)c1cc(C=O)c(O)cc1Cl.O=C1CCC(=O)N1Br>>CC(C)(C)c1cc(C=O)c(O)c(Br)c1Cl,,ClCCl,,,,test
US20010012901A1,CCOC(=O)CCCOc1cc(C)c(S(=O)(=O)Cl)c(C)c1C.N=C(N)c1ccccc1>>CCOC(=O)CCCOc1cc(C)c(S(=O)(=O)NC(=N)c2ccccc2)c(C)c1C,,CC(C)=O,,Cl,[Na+].[OH-],test
US04983723,CC(=O)C=CC1=C(C)CC(O)CC1(C)C.CC(C)(C)[Si](C)(C)Cl>>CC(=O)C=CC1=C(C)CC(O[Si](C)(C)C(C)(C)C)CC1(C)C,,CCOCC,,CN(C)C=O,c1c[nH]cn1,test
US20070054897A1,CCC(=O)N1CCNCC1.O=Cc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1>>CCC(=O)N1CCN(Cc2cnc(NC(=O)N(C3CCCCC3)C3CCCCC3)s2)CC1,,CC(=O)O,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05047411,CCOC(=S)[S-].Cc1ccn2c(C)c(CCc3ccc(N)c(O)c3)nc2c1.[K+]>>Cc1ccn2c(C)c(CCc3ccc4nc([S-])oc4c3)nc2c1.[K+],,CCO,,,,test
US06440995B1,O=P(Cl)(Cl)Cl.Oc1cc(O)c2ccccc2n1.c1ccc2c(c1)CCNC2>>Clc1cc(N2CCc3ccccc3C2)c2ccccc2n1,,CO,ClCCl,[Na+].[OH-],,test
US20090137561A1,C1CCNCC1.COC(=O)c1ccc(-c2cc(OC)ccc2F)c(CBr)c1>>COC(=O)c1ccc(-c2cc(OC)ccc2F)c(CN2CCCCC2)c1,,CS(C)=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20050080096A1,CC(C)(C)OC(=O)N1CC=C(c2ccc(F)c(F)c2)CC1.Cl>>Cl.Fc1ccc(C2=CCNCC2)cc1F,,CCOC(C)=O,,,,test
US20130252937A1,COC(=O)COc1cc(C)c(-c2ccc(F)c3c2CC[C@H]3Oc2ccc3c(c2)OC[C@H]3CC(=O)O)c(C)c1.N>>Cc1cc(OCC(N)=O)cc(C)c1-c1ccc(F)c2c1CC[C@H]2Oc1ccc2c(c1)OC[C@H]2CC(=O)O,,C1COCCO1,,,,test
US20060194801A1,COC(=O)c1ccc(C#CC(C)(C)C)cn1>>CC(C)(C)C#Cc1ccc(C(=O)O)nc1,,O,,CO,[Li+].[OH-],test
US05834506,Cc1ccc(S(=O)(=O)Sc2cc(C)c(CO)cc2C(C)(C)C)cc1.O=C1C=C(O)C[C@@](CCc2ccccc2)(c2ccccc2)O1>>Cc1cc([SH](C2=C(O)CC(CCc3ccccc3)(c3ccccc3)OC2=O)C(C)(C)C)ccc1CO,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06177440B1,COC(=O)COc1cccc2c1c1c(C(N)=O)cccc1n2Cc1ccccc1C#N>>N#Cc1ccccc1Cn1c2cccc(OCC(=O)O)c2c2c(C(N)=O)cccc21,,CCO,,[Na+].[OH-],,test
US20100016252A1,C=O.CNC.c1ccc2[nH]ccc2c1>>CN(C)Cn1ccc2ccccc21,,ClCCl,,,,test
US04209517,CC(=O)CCC=C(C)C.O=Cc1ccc2c(c1)OCO2>>CC(C)=CCCC(=O)C=Cc1ccc2c(c1)OCO2,,[Na+],[OH-],,,test
US04742063,CCCCCCSc1nnc(N)s1.CCOC(=O)CC(=O)c1ccccc1>>CCCCCCSc1nn2c(=O)cc(-c3ccccc3)nc2s1,,O,,ClC(Cl)Cl,,test
US20070254901A1,COC(=O)Cc1ccccc1.CSc1ncc(C=O)c(N)n1.O=P(Cl)(Cl)Cl>>CSc1ncc2cc(-c3ccccc3)c(Cl)nc2n1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US06479660B1,COc1ccc2[nH]c(=O)cc(C)c2c1Cl.O=[N+]([O-])O>>COc1cc([N+](=O)[O-])c2[nH]c(=O)cc(C)c2c1Cl,,O=S(=O)(O)O,,O,,test
US05463053,C[C@H](c1ccccc1)N1CC(=NO)C(C)(C)C1=O>>C[C@H](c1ccccc1)N1CC(N)C(C)(C)C1=O,[Ni],CO,,,,test
US20120101100A1,CCNC(=O)Nc1cc(C(=O)OC)c(B2OC(C)(C)C(C)(C)O2)cn1.N>>CCNC(=O)Nc1cc(C(N)=O)c(B(O)O)cn1,,CO,,,,test
US20100267666A1,COc1cc(-c2cnc3c(n2)c(C(O)C(C)(C)CC#N)cn3[Si](C(C)C)(C(C)C)C(C)C)cc(OC)c1OC>>COc1cc(-c2cnc3c(n2)c(C(=O)C(C)(C)CC#N)cn3[Si](C(C)C)(C(C)C)C(C)C)cc(OC)c1OC,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20070259877A1,COc1ccc(N2C[C@H](C)N[C@H](C)C2)cc1[N+](=O)[O-]>>COc1ccc(N2C[C@H](C)N[C@H](C)C2)cc1N,[Pd],CCO,,,,test
US20140228343A1,[NH4+].c1ccc2c(c1)CCN(CC1CO1)C2>>NCC(O)CN1CCc2ccccc2C1,,CCO,,,,test
US20160046624A1,Cn1c(=O)n(CCCOC2CCCCO2)c(=O)c2c(C(O)c3ccc(F)cc3)c(Oc3ccc(Cl)cc3)cnc21.O=CO>>Cn1c(=O)n(CCCOC=O)c(=O)c2c(Cc3ccc(F)cc3)c(Oc3ccc(Cl)cc3)cnc21,[Zn],O=CO,,,,test
US20080051404A1,CN(c1cc(Cl)ncn1)[C@@H]1C[C@H](CO)[C@H]2OC(C)(C)O[C@H]21.N[C@H]1CCc2ccccc21>>CN(c1cc(N[C@H]2CCc3ccccc32)ncn1)[C@@H]1C[C@H](CO)[C@H]2OC(C)(C)O[C@H]21,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20150148340A1,CCOC=C(C(=O)NC(=O)OCC)C(=O)OCC.Nc1ccc2ncsc2c1>>CCOC(=O)c1cn(-c2ccc3ncsc3c2)c(=O)[nH]c1=O,,O,,Cl,,test
US20070082907A1,CCOC(=O)COc1ccc(Oc2cccc(C(=O)O)c2)cc1C.O=C(Cl)C(=O)Cl>>CCOC(=O)COc1ccc(Oc2cccc(C(=O)Cl)c2)cc1C,CN(C)C=O,ClCCl,,,,test
US05925656,Cc1c(C)c2c(c(C)c1OCc1ccccc1)CCC(C)(CN(C)CCOc1ccc(C=C3SC(=O)NC3=O)cc1)O2>>Cc1c(C)c2c(c(C)c1O)CCC(C)(CN(C)CCOc1ccc(C=C3SC(=O)NC3=O)cc1)O2,,CC(=O)O,,Cl,,test
US20120309738A1,CNc1cc(N2CCC(C(F)(F)F)CC2)c(C#N)cc1[N+](=O)[O-]>>CNc1cc(N2CCC(C(F)(F)F)CC2)c(C#N)cc1N,[Pd],CCO,,CCOC(C)=O,,test
US20060276508A1,CCOC(=O)C(C)(C)Oc1cc(OC)cc(C(=O)NC2CCNCC2)c1.CCOc1cc(C=O)ccc1OC>>CCOC(=O)C(C)(C)Oc1cc(OC)cc(C(=O)NC2CCN(Cc3ccc(OC)c(OCC)c3)CC2)c1,,CC(=O)O,CCO,CCN(C(C)C)C(C)C,[BH3-]C#N.[Na+],test
US20160137653A1,N[C@@H]1CC[C@@H](c2ccccc2)CC1.O=C=Nc1ccc(Cl)cc1>>O=C(Nc1ccc(Cl)cc1)N[C@@H]1CC[C@@H](c2ccccc2)CC1,,CCOCC,,,,test
US04282242,CCc1cc(C(O)=S)c(C)[nH]1>>CCc1cc(C(O)=S)c[nH]1,,CCO,,[Na+].[OH-],,test
US20060116400A1,O=C(Cl)c1ccc([N+](=O)[O-])cc1.O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(-c2ccc(C3=NOC(CO)C3)nc2)c(F)c1>>O=C(OCC1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1)c1ccc([N+](=O)[O-])cc1,,CO,ClCCl,CCN(CC)CC,CN(C)C=O,test
US20160060273A1,CC(C)(C)[Si](C)(C)Cl.CCOc1cc(CO)cc(OS(=O)(=O)C(F)(F)F)c1-c1ccc(F)cc1>>CCOc1cc(CO[Si](C)(C)C(C)(C)C)cc(OS(=O)(=O)C(F)(F)F)c1-c1ccc(F)cc1,,CCOC(C)=O,O,CN(C)C=O,c1c[nH]cn1,test
US20120059002A1,C=Cc1ccc2nc(-c3cc(C)c(O)c(C)c3)[nH]c(=O)c2c1.O=[Os](=O)(=O)=O>>Cc1cc(-c2nc3ccc(C=O)cc3c(=O)[nH]2)cc(C)c1O,O=[Os](=O)(=O)=O,O,,C1CCOC1,,test
US20040029734A1,CCOC(=O)/C=C(\N)C(F)(F)F.CI.O=C=Nc1ccc(Cl)c2ccccc12>>Cn1c(C(F)(F)F)cc(=O)n(-c2ccc(Cl)c3ccccc23)c1=O,,CN(C)C=O,Cc1ccccc1,[H-].[Na+],,test
US20120178715A1,Clc1ccn2ncc(Br)c2n1.O=C1N[C@@H](c2ccccc2Cl)CO1>>O=C1OC[C@H](c2ccccc2Cl)N1c1ccn2ncc(Br)c2n1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20040110832A1,CC1CNCC(C)C1.N#Cc1cc(Cl)ccc1F>>CC1CC(C)CN(c2ccc(Cl)cc2C#N)C1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],test
US07495007B2,COC(=O)C(C)(C)COc1ccc(Br)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12>>Cc1ccc(F)cc1C1NC(=O)CC(c2cc(Br)ccc2OCC(C)(C)CO)C12C(=O)Nc1cc(Cl)ccc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20160031888A1,CCN(CC)CCNC(=O)c1c(C)[nH]c(C=O)c1C.O=C1Cc2cc(-c3ccc(-c4ccccc4)s3)ccc2N1>>CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(-c4ccc(-c5ccccc5)s4)cc32)c1C,,C1CCOC1,CCO,C1CCNCC1,,test
US20150353499A1,COc1ccc(F)cc1CBr.C[C@@H](C(=O)N[C@H]1CCc2ccccc2NC1=O)N(C)C(=O)OC(C)(C)C>>COc1ccc(F)cc1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)CCc2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050020652A1,CC(C)c1ccc(CCl)cc1.CCOC(=O)C(C)(Cc1ccc(OCCC2CNC(=O)N2C)cc1)Oc1ccccc1>>CC(C)c1ccc(CN2CC(CCOc3ccc(CC(C)(Oc4ccccc4)C(=O)O)cc3)N(C)C2=O)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20140275071A1,Cn1c(=O)n(CCCO)c(=O)c2c1nc(C(=O)c1cccc(OC(F)(F)F)c1)n2Cc1ccc(Cl)cc1>>Cn1c(=O)n(CCCO)c(=O)c2c1nc(C(O)c1cccc(OC(F)(F)F)c1)n2Cc1ccc(Cl)cc1,,CO,,[BH4-].[Na+],,test
US20140038999A1,Cn1c(=O)c2cnccc2c2ccc(Cl)cc21.O=C(OO)c1cccc(Cl)c1>>Cn1c(=O)c2c[n+]([O-])ccc2c2ccc(Cl)cc21,,ClCCl,ClCCl,,,test
US07001904B1,O=c1[nH]cnc2cc(F)ccc12.OCCN1CCOCC1>>O=c1[nH]cnc2cc(OCCN3CCOCC3)ccc12,,CN(C)C=O,,[H-].[Na+],,test
US03950528,CCOC(=O)C=C(N)OCC.NNCc1ccccc1[N+](=O)[O-]>>Nc1cc(=O)n(Cc2ccccc2[N+](=O)[O-])[nH]1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040127482A1,Cl.NN1CCc2ccccc21.O=C1CCCCN1>>Cl.c1cc2c3c(c1)c1c(n3CC2)CCNC1,,CC(C)O,,O,,test
US20100041722A1,NO.O=Cc1cncn1C1Cc2ccccc2C1>>ON=Cc1cncn1C1Cc2ccccc2C1,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US04542142,C#CC(O)c1cccc(Oc2ccccc2)c1.CC1(C)[C@@H](/C=C\C(=O)OCCF)[C@H]1C(=O)O>>C#CC(OC(=O)[C@@H]1[C@H](/C=C\C(=O)OCCF)C1(C)C)c1cccc(Oc2ccccc2)c1,,ClC(Cl)Cl,,,,test
US20120220589A1,COC(=O)c1ccc2nc(-c3ccc(F)cc3)c(N3CCCc4cc(Cl)ccc43)nc2c1>>O=C(O)c1ccc2nc(-c3ccc(F)cc3)c(N3CCCc4cc(Cl)ccc43)nc2c1,,CO,O,[Na+].[OH-],,test
US20010047038A1,CC(=O)O.COC(=O)c1ccc(N)cc1OC>>COC(=O)c1ccc(NC(C)=O)cc1OC,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20160000760A1,CC1(C)OB(c2ccc(S(=O)(=O)N3CC4(COC4)C3)cc2)OC1(C)C.Nc1nc(Nc2cc(Cl)c(Br)c(C(F)(F)F)c2)n[nH]1>>Nc1nc(Nc2cc(Cl)c(-c3ccc(S(=O)(=O)N4CC5(COC5)C4)cc3)c(C(F)(F)F)c2)n[nH]1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20110319378A1,C=CC(=O)OC.O=C(Cc1cccc(Cl)c1)c1ccc(Cl)s1>>COC(=O)CCC(C(=O)c1ccc(Cl)s1)c1cccc(Cl)c1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20110053911A1,Cc1c(C(=O)O)cc(F)cc1[N+](=O)[O-]>>Cc1c(N)cc(F)cc1C(=O)O,[Pd],CO,,,,test
US20120101100A1,CCNC(=O)Nc1cc(-c2nc(-c3ccccc3)cs2)c(B(O)O)cn1.CCOC(=O)c1cncc(B2OC(C)(C)C(C)(C)O2)c1>>CCNC(=O)Nc1cc(-c2nc(-c3ccccc3)cs2)c(-c2cncc(C(=O)OCC)c2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060281932A1,CC[Si](Cl)(CC)CC.C[Si](C)(C)OCC(=O)O[Si](C)(C)C>>CC[Si](CC)(CC)OC(CO[Si](C)(C)C)O[Si](C)(C)C,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20160152609A1,CCOC(=O)c1ncn2c1CCc1cc(OC)c(CC(C)C)cc1-2.O=C1CCC(=O)N1Br>>CCOC(=O)c1nc(Br)n2c1CCc1cc(OC)c(CC(C)C)cc1-2,,CC#N,,O=C([O-])O.[Na+],,test
US20040204397A1,COC(=O)[C@@H](Cc1ccc2[nH]c(=O)oc2c1)NC(=O)OCc1ccccc1.O=C1CCC(=O)N1Br>>COC(=O)[C@@H](Cc1cc(Br)c2[nH]c(=O)oc2c1)NC(=O)OCc1ccccc1,,ClCCl,,,,test
US20100087427A1,CC(=O)Cl.COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2NS(=O)(=O)Cc2cccc(N)c2)C(C)C)ccc1OC>>COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2NS(=O)(=O)Cc2cccc(NC(C)=O)c2)C(C)C)ccc1OC,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20130172551A1,COc1c2n(cc(C(=O)O)c1=O)C[C@H]1OC[C@H](C)N1C2=O.NCc1ccc(F)cc1F>>COc1c2n(cc(C(=O)NCc3ccc(F)cc3F)c1=O)C[C@H]1OC[C@H](C)N1C2=O,,COCCOC,,O=C(n1ccnc1)n1ccnc1,,test
US20140275121A1,CCc1ccc(Br)cc1C(=O)OC.O=C1CCC(=O)N1Br>>COC(=O)c1cc(Br)ccc1C(C)Br,CC(C)(C#N)N=NC(C)(C)C#N,ClC(Cl)(Cl)Cl,,,,test
US20160185777A1,CCOC(=O)c1n[nH]c2c1CN(C(=O)OC(C)(C)C)CC2>>CCOC(=O)c1n[nH]c2c1CNCC2,,C1COCCO1,,,,test
US05643878,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O.[NH-]N1CCOCC1>>CC(C)[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O.[NH-]N1CCOCC1,[Pd],CO,,,,test
US20020013337A1,O=C(N[C@@H](CCO)c1ccccc1)OCc1ccccc1>>O=CC[C@H](NC(=O)OCc1ccccc1)c1ccccc1,,Cc1ccccc1,ClCCl,CCN(CC)CC,CS(C)=O,test
US05510319,O=C(O)c1cccnc1C(=O)O>>O=C1OC(=O)c2ncccc21,,CC(=O)OC(C)=O,,,,test
US20110224188A1,CCOC(CBr)OCC.C[C@H](NC(=O)c1cnc2n1[C@](C)(Cc1ccc(C#N)cc1)C(=O)N2c1cc(Cl)cc(Cl)c1)C(=O)N[C@H](C)C(N)=S>>CC(NC(=O)[C@H](C)NC(=O)c1cnc2n1[C@](C)(Cc1ccc(C#N)cc1)C(=O)N2c1cc(Cl)cc(Cl)c1)c1nccs1,C1COCCO1,CC(C)=O,,Cl,,test
US20090029905A1,C1COCCN1.C[C@@H](CO[Si](C)(C)C(C)(C)C)Oc1cc(Oc2ncc(C(=O)O)cc2Cl)cc(C(=O)Nc2ccn(C)n2)c1>>C[C@@H](CO)Oc1cc(Oc2ncc(C(=O)N3CCOCC3)cc2Cl)cc(C(=O)Nc2ccn(C)n2)c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04788206,CC/C(=C\C=O)c1ccc(OC)cc1.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CC/C(=C\C=C\C(=O)OC)c1ccc(OC)cc1,,ClC(Cl)(Cl)Cl,ClCCl,,,test
US05703087,N#CCCl.NCCOCc1ccccc1>>N#CCNCCOCc1ccccc1,,C1CCOC1,,CCN(CC)CC,,test
US20120029026A1,COC(=O)c1cccc(OCc2nc3ccc(O)cc3n2C)c1.Fc1nc(Br)c(Br)cc1Br>>COC(=O)c1cccc(OCc2nc3ccc(Oc4nc(Br)c(Br)cc4Br)cc3n2C)c1,I[Cu]I,CN(C)C=O,,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US20070173537A1,CCOC(=O)N1CCC(O)(c2ccc(Cl)c(C(F)(F)F)c2)CC1.CI>>COC1(c2ccc(Cl)c(C(F)(F)F)c2)CCNCC1,,CN(C)C=O,,O,[H-].[Na+],test
US04370497,COc1ccc([Te](=O)c2ccc(OC)cc2)cc1.ONc1ccccc1>>COc1ccc([Te]c2ccc(OC)cc2)cc1.O=Nc1ccccc1,,ClC(Cl)Cl,,,,test
US20110319379A1,CCS(=O)(=O)NC.Clc1cnc(Cl)cn1>>CCS(=O)(=O)N(C)c1cnc(Cl)cn1,,CO,,[K+].[OH-],,test
US20160214964A1,C#Cc1cccc(Nc2ncnc3cc(OC)c([N+](=O)[O-])cc23)c1>>C#Cc1cccc(Nc2ncnc3cc(OC)c(N)cc23)c1,[Fe],CCO,,[Cl-].[NH4+],,test
US20040171606A1,CC(=O)c1ccc2c(c1)CCN(C(=O)OC(C)(C)C)CC2.NO>>CC(=NO)c1ccc2c(c1)CCN(C(=O)OC(C)(C)C)CC2,,c1ccncc1,,Cl,,test
US20090186884A1,CC(C)(C)OC(=O)N[C@@H](CC1CCCCC1)[C@H]1CO1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N[C@@H](CC1CCCCC1)[C@H](O)CN=[N+]=[N-],,CO,,[Cl-].[NH4+],,test
US20100234441A1,COC(=O)c1c(F)cccc1OC(F)F>>O=C(O)c1c(F)cccc1OC(F)F,,C1COCCO1,O,[Li+].[OH-],,test
US20040220177A1,CC(C)(C)OC(=O)N1CC=C(c2c[nH]c3ccc([N+](=O)[O-])cc23)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CC=C(c2cn(S(C)(=O)=O)c3ccc([N+](=O)[O-])cc23)CC1,,Cc1ccccc1,,CCOC(C)=O,[Na+].[OH-],test
US05298652,BrCCCCCCCCCCCCOc1ccccc1.CCOC(=O)C(=O)c1ccc(O)cc1>>CCOC(=O)C(=O)c1ccc(OCCCCCCCCCCCCOc2ccccc2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20060252767A1,CCCCCN.COC(=O)c1cnc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)cn1>>CCCCCNC(=O)c1cnc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)cn1,,O,,CC(C)(C)[O-].[K+],,test
US20140315886A1,N=C(N)c1cccnc1.O=c1[nH]c2c(F)c(Cl)ccc2c(=O)o1>>Oc1nc(-c2cccnc2)nc2c(F)c(Cl)ccc12,,CO,c1ccncc1,Cl,Cl,test
US20150133451A1,Cc1nc(C(=O)Nc2cn(C)nc2N2C[C@@H](O[Si](C)(C)C(C)(C)C)CC2=O)co1>>Cc1nc(C(=O)Nc2cn(C)nc2N2C[C@@H](O)CC2=O)co1,,C1CCOC1,O,,,test
US20090131458A1,BrCC[C@@H]1CCOC1.CCCCNc1nc(N)c2nc(OC)nc-2[nH]1>>CCCCNc1nc(N)c2nc(OC)n(CC[C@@H]3CCOC3)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US03947417,CCOC(=O)C(Br)N=Nc1ccc(Cl)cc1C(=O)c1ccccc1.N>>CCOC(=O)C(N)N=Nc1ccc(Cl)cc1C(=O)c1ccccc1,,CCOCC,,,,test
US20020169192A1,CCCCCCCNCCc1cccc(OC(C)(CC)C(=O)OCc2ccccc2)c1.O=C=Nc1ccc(F)cc1F>>CCCCCCCN(CCc1cccc(OC(C)(CC)C(=O)OCc2ccccc2)c1)C(=O)Nc1ccc(F)cc1F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120214848A1,CC(C)Oc1ccc(-c2noc(-c3ccc(C(C)(C)NCCC(=O)O)cc3)n2)cc1Cl.CO>>CC(C)Oc1ccc(-c2noc(-c3ccc(C(C)(C)NCCC(=O)O)cc3)n2)cc1Cl.CO,,CO,,,,test
US04034098,CS(=O)(=O)Cl.NC1CCN(CCCC(=O)c2ccccc2)CC1>>CS(=O)(=O)NC1CCN(CCCC(=O)c2ccccc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20130296290A1,CC(C)(C)OC(=O)NCCc1nnc([C@@H]2CC[C@@H]3CN2C(=O)N3OCc2ccccc2)o1.O=C(O)C(F)(F)F>>NCCc1nnc([C@@H]2CC[C@@H]3CN2C(=O)N3OCc2ccccc2)o1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US05081118,CCOC(=O)Cl.OCCI>>CCOC(=O)OCCI,,c1ccccc1,,c1ccncc1,,test
US05103036,CCOCC.CCOP(=O)(CP(=O)(OCC)OCC)OCC.C[Si](C)(C)C(C(N)=O)[Si](C)(C)C.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCOP(=O)(OCC)C(C/C=C/c1ccc(-c2ccccc2)cc1)P(=O)(OCC)OCC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,CCOCC,,,test
US20060052599A1,CCOC(=O)/C=C/c1ccc(NC2CCN(Cc3ccccc3)C2)nc1>>O=C(O)/C=C/c1ccc(NC2CCN(Cc3ccccc3)C2)nc1,,CO,,[Na+].[OH-],,test
US04472433,CCOC(=O)Cc1cccc(Oc2ccccc2C)c1[N+](=O)[O-]>>Cc1ccccc1Oc1cccc(CC(=O)O)c1[N+](=O)[O-],,CO,,[K+].[OH-],,test
US20140200231A1,O=C(OCCCCl)N1Cc2cnc(NC3Cc4ccccc4C3)nc2C1.c1c[nH]cn1>>O=C(OCCCn1ccnc1)N1Cc2cnc(NC3Cc4ccccc4C3)nc2C1,,CN(C)C=O,ClCCl,[H-].[Na+],,test
US20130210796A1,C=O.C[C@H]1CNC[C@@H](C)O1.C[Si](C)(C)N=[N+]=[N-].[C-]#[N+]c1ccc(C#N)cc1>>C[C@H]1CN(Cc2nnnn2-c2ccc(C#N)cc2)C[C@@H](C)O1,,CO,,,,test
US20060063787A1,CC#CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc(C=O)c1C(=O)OCC.CNN>>CC#CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2cnn(C)c(=O)c21,,CCO,,,,test
US20080096968A1,O=C(O)C1(c2ccc(-c3ccc(O)cc3)c(F)c2)CC1.OC1CCC(C(F)(F)F)CC1>>O=C(O)C1(c2ccc(-c3ccc(OC4CCC(C(F)(F)F)CC4)cc3)c(F)c2)CC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090105253A1,CCNC(=O)c1ccc(-n2nnc(C(=O)O)c2-c2cccs2)cc1.NC1CC1>>CCNC(=O)c1ccc(-n2nnc(C(=O)NC3CC3)c2-c2cccs2)cc1,,CCN(CC)CC,CN(C)C=O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US05143928,CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O.COc1ccc(/C=C2\SC(=N)NC2=O)cc1OC1CCCC1>>CC(C)(C)c1cc(C=C2SC(=N)NC2=O)cc(C(C)(C)C)c1O,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20110312979A1,CON(C)C(=O)c1cc2cccnc2[nH]1.OB(O)c1cccc(F)c1>>CON(C)C(=O)c1cc2cccnc2n1-c1cccc(F)c1,,ClCCl,,c1ccncc1,,test
US20160052920A1,CCOC(=O)C(F)Br.CC[Si](CC)(CC)c1cc(Br)nc(/C(C)=N/[S@](=O)C(C)(C)C)c1F>>CCOC(=O)[C@H](F)[C@](C)(N[S@](=O)C(C)(C)C)c1nc(Br)cc([Si](CC)(CC)CC)c1F,[Zn],C1CCOC1,,,,test
US20150133446A1,CC(C)(C)OC(=O)N1CCC[C@H]1CO.CSc1nn2cc(-c3nc4c(O)cccc4o3)nc2s1>>CSc1nn2cc(-c3nc4c(OC[C@@H]5CCCN5C(=O)OC(C)(C)C)cccc4o3)nc2s1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090054555A1,CCOC(=O)CCCCCCCCCCCO.O=C1CCC(=O)N1Br>>CCOC(=O)CCCCCCCCCCCBr,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140371068A1,CCI.Cc1c(C(=O)Nc2nnnn2C)ccc(C(F)(F)F)c1S(C)(=O)=O>>CCN(C(=O)c1ccc(C(F)(F)F)c(S(C)(=O)=O)c1C)c1nnnn1C,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20160002175A1,Cc1cccc(B(O)O)c1Cl.Nc1nc(Cl)cc(Cl)n1>>Cc1cccc(-c2cc(Cl)nc(N)n2)c1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US05521177,CCCc1nc2c(C)cc(Nc3[nH]ccc3[N+](=O)[O-])cc2n1Cc1ccc(-c2ccccc2C(=O)OC)cc1>>CCCc1nc2c(C)cc(Nc3[nH]ccc3[N+](=O)[O-])cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1,,CCO,,[Na+].[OH-],,test
US20080242661A1,CCOC(=O)C1C=C(C2CCCC2)NN1C>>CN1NC(C2CCCC2)=CC1C(=O)O,,O,,Cl,[Na+].[OH-],test
US20090137530A1,CCCCCCCO.N#Cc1cc(Br)ccc1F>>CCCCCCCOc1ccc(Br)cc1C#N,,CN(C)C=O,,O,[H-].[Na+],test
US05488152,O=C1OC(=O)c2c(F)c(F)c(F)c(F)c21.OCC(F)(F)F>>O=C(O)c1cc(F)c(F)c(OCC(F)(F)F)c1F,,O,,[Li+].[OH-],,test
US20130123289A1,CC(C)(CNc1ncc(-c2ccc(F)c(C#N)c2)cn1)c1ccc(F)cc1.NN>>CC(C)(CNc1ncc(-c2ccc3[nH]nc(N)c3c2)cn1)c1ccc(F)cc1,,CCCO,,,,test
US20060052371A1,CC(=O)Nc1cccc(C#N)c1.COC(=O)c1ccccc1S>>CC(=O)Nc1cccc(-c2nc(=O)c3ccccc3s2)c1,,Cc1ccccc1,,CCN(CC)CC,,test
US05703240,Cc1nnnn1-c1ccc(OCc2ccccc2)c(F)c1>>Cc1nnnn1-c1ccc(O)c(F)c1,[Pd],CCO,,,,test
US20090156571A1,O=C(c1ccc(-c2cc(Cl)c(CC3CCN(C4CCCCC4)C3=O)c(Cl)c2)cc1)N1CCNCC1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>O=C(c1ccc(-c2cc(Cl)c(CC3CCN(C4CCCCC4)C3=O)c(Cl)c2)cc1)N1CCN(CC(F)(F)F)CC1,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20120258952A1,Cc1cc(CCl)nn1C.O=[N+]([O-])c1cccc2[nH]nc(I)c12>>Cc1cc(Cn2nc(I)c3c([N+](=O)[O-])cccc32)nn1C,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080153850A1,C[Si](C)(C)N=[N+]=[N-].N#Cc1nccnc1-c1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1>>O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(-c2nccnc2-c2nnn[nH]2)ccc1Cl,,Cc1ccccc1,,CCCC[Sn](=O)CCCC,,test
US20090054434A1,CCn1cc(Br)c2cc(OC)c(OC)cc2c1=O.Cc1cc(B(O)O)cnc1F>>CCn1cc(-c2cnc(F)c(C)c2)c2cc(OC)c(OC)cc2c1=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20100184739A1,CC(C)c1cc(C(F)(F)F)c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1OCc1ccccc1>>CC(C)c1cc(C(F)(F)F)c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O,[Pd],,,,,test
US05856314,CCOP(=O)(OCC)C(Nc1ccc([N+](=O)[O-])cn1)P(=O)(OCC)OCC>>CCOP(=O)(OCC)C(Nc1ccc(N)cn1)P(=O)(OCC)OCC,[Pd],CCO,,,,test
US05409666,O=Cc1ccc2ccc3cccc4ccc1c2c34>>OCc1ccc2ccc3cccc4ccc1c2c34,,CCO,,O,[BH4-].[Na+],test
US20090069323A1,COC(=O)c1cc(F)cc(Br)c1.N#C[Cu]C#N>>COC(=O)c1cc(F)cc(C#N)c1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20070032485A1,CC[C@@H]1C[C@H](Nc2ncc(N3CCOCC3)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)c2nc(OC)ccc2N1.O=C=NCCCl>>CC[C@@H]1C[C@H](Nc2ncc(N3CCOCC3)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)c2nc(OC)ccc2N1C(=O)NCCCl,,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US05962453,CS(=O)(=O)Cl.Cl.NCC1CCN(c2nc(N)nc(-c3cc(Cl)ccc3Cl)n2)C1>>CS(=O)(=O)NCC1CCN(c2nc(N)nc(-c3cc(Cl)ccc3Cl)n2)C1.Cl,,C1CCOC1,,Cl,O=C([O-])[O-].[K+].[K+],test
US20070066618A1,Cc1cc([N+](=O)[O-])c(Cl)nc1C.Nc1ccc(CCO)cc1>>Cc1cc([N+](=O)[O-])c(Nc2ccc(CCO)cc2)nc1C,,CCOC(C)=O,Cc1ccccc1,Cc1cccc(C)n1,,test
US20040002532A1,CCOC(=O)C(C(=O)c1ccc(S(C)(=O)=O)cc1)c1ccc(OC)cc1.CNNC>>COc1ccc(-c2c(-c3ccc(S(C)(=O)=O)cc3)n(C)n(C)c2=O)cc1,,Cc1ccccc1,O,,,test
US20130217759A1,CCOC(=O)c1c(NS(=O)(=O)c2ccccc2C(F)(F)F)sc2c1CCCC2>>O=C(O)c1c(NS(=O)(=O)c2ccccc2C(F)(F)F)sc2c1CCCC2,,C1COCCO1,O,[Li+].[OH-],,test
US20160052884A1,COc1cc(B(O)O)ccn1.C[Si](C)(C)C#Cc1ccc(Cl)cc1Br>>COc1cc(-c2cc(Cl)ccc2C#C[Si](C)(C)C)ccn1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US05389651,CCC(C)Oc1ccc(OC(C)CO)cc1.Clc1ccccn1>>CCC(C)Oc1ccc(OC(C)COc2ccccn2)cc1,,C1CCOC1,CN(C)P(=O)(N(C)C)N(C)C,[H-].[Na+],,test
US05023341,Cc1cc2c(cc1C#C[Si](C)(C)C)C(C)(C)CCS2>>C#Cc1cc2c(cc1C)SCCC2(C)C,,CC(C)O,,[K+].[OH-],,test
US20100267666A1,C#Cc1ccccc1.COc1cc(-c2cnc3[nH]cc(I)c3n2)cc(OC)c1OC>>COc1cc(-c2cnc3[nH]cc(C#Cc4ccccc4)c3n2)cc(OC)c1OC,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,CCN(CC)CC,,test
US20090047246A1,COC(=O)Cc1c(C(=O)c2ccccc2-c2ccccc2)sc2ccccc12>>O=C(O)Cc1c(C(=O)c2ccccc2-c2ccccc2)sc2ccccc12,,C1CCOC1,CO,O,[K+].[OH-],test
US20090062342A1,COCCCc1cc(C=NC2CC2)c(Cl)cn1>>COCCCc1cc(CNC2CC2)c(Cl)cn1,,CO,,[BH4-].[Na+],,test
US20070051919A1,Fc1cccc(C=Cc2ccc3ccccc3c2)c1>>Fc1cccc(CCc2ccc3ccccc3c2)c1,[Pd],Cc1ccccc1,,,,test
US20140350019A1,Cc1cc(Br)cc(C(=O)O)c1F.OB(O)c1cccc(F)c1>>Cc1cc(-c2cccc(F)c2)cc(C(=O)O)c1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,O,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20140213580A1,CS(=O)(=O)Cl.N#Cc1cc(-c2cn[nH]c2)c(C2CC2)nc1N1CCN(C(=O)C2CC2)[C@H](C2CC2)C1>>CS(=O)(=O)n1cc(-c2cc(C#N)c(N3CCN(C(=O)C4CC4)[C@H](C4CC4)C3)nc2C2CC2)cn1,,ClCCl,,,,test
US20080267887A1,CCI.CCOC(=O)CCc1cn(-c2ccc(C(C)C)cc2)c2cnc(-c3c(CC)cccc3CC)cc12.CCc1ccccc1>>CCOC(=O)C(CC)(CC)Cc1cn(-c2ccc(C(C)C)cc2)c2cnc(-c3c(CC)cccc3CC)cc12,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20160222014A1,CN(C(=O)OC(C)(C)C)C1CCN(c2ccc([N+](=O)[O-])cc2)CC1.Cl>>CNC1CCN(c2ccc([N+](=O)[O-])cc2)CC1.Cl,,C1COCCO1,ClCCl,CCOCC,,test
US20070049593A1,c1ccc(COc2ccccc2OCCOC2CCCCO2)cc1>>OCCOc1ccccc1OCc1ccccc1,,C1CCOC1,CO,Cl,O,test
US04254260,CCOC(=O)Cc1cnc(N)s1.CS(=O)(=O)Cl>>CCOC(=O)Cc1cnc(NS(C)(=O)=O)s1,,ClCCl,,c1ccncc1,,test
US20120015443A1,CCCCCCCCCCC(O)CN[C@@H](CC(=O)O)c1ccccc1>>CCCCCCCCCCC(O)CNC(CC(=O)O)c1ccccc1,,CO,,,,test
US04409229,O=C(Cl)C1CC1.c1ccc(C2SC3(CCNCC3)c3ccccc32)cc1>>O=C(C1CC1)N1CCC2(CC1)SC(c1ccccc1)c1ccccc12,,ClCCl,,O=C([O-])O.[Na+],,test
US04691027,CN(C)CCO.COCOc1c(C)c(C)c2c(c1C)SC(CCCBr)O2>>COCOc1c(C)c(C)c2c(c1C)SC(CCCOCCN(C)C)O2,,CS(C)=O,,[H-].[Na+],,test
US06005116,CC(O)c1c(OCCNC(=O)OC(C)(C)C)noc1-c1ccccc1>>CC(=O)c1c(OCCNC(=O)OC(C)(C)C)noc1-c1ccccc1,,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20150141402A1,O=[N+]([O-])c1c(Cl)nc(Cl)nc1NC1CCC1>>Nc1c(Cl)nc(Cl)nc1NC1CCC1,[Fe],CC(=O)O,,,,test
US20080249301A1,COC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1ccccc1C(F)(F)F.[NH4+]>>NC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1ccccc1C(F)(F)F,,CO,,,,test
US20080119539A1,COC(=O)c1ccc(CCCO)s1.II>>COC(=O)c1ccc(CCCI)s1,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110195948A1,O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC(O)C1.O=S(=O)(O)O>>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC(O)C1.O=S(=O)(O)O,,CO,,,,test
US20040171075A1,O=C(Cc1cccc([N+](=O)[O-])c1)N1CCOCC1>>Nc1cccc(CC(=O)N2CCOCC2)c1,[Pd],CCO,,,,test
US04734418,CCNCC.CCNc1nc(N2CCN(Cc3ccccc3)CC2)ncc1C(=O)O>>CCNc1nc(N2CCN(Cc3ccccc3)CC2)ncc1C(=O)N(CC)CC,,ClC(Cl)Cl,O,CCN(CC)CC,O=S(Cl)Cl,test
US20150005289A1,CC(C)(C)OC(=O)N1CCC(O)(c2ccc3nc(O)cc(=O)n3c2)CC1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCC(O)(c2ccc3nc(OS(=O)(=O)C(F)(F)F)cc(=O)n3c2)CC1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20130029846A1,CCN(C)C=Nc1ccc2c(c1)CC(C)N2.CON=C(CBr)COc1cccc(C(F)(F)F)c1>>CCN(C)C=Nc1ccc2c(c1)CC(C)N2CC(COc1cccc(C(F)(F)F)c1)=NOC,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US06083961,COc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)/C=C/c4ccc(N)nc4)c3Cl)cccc2n1C.Cc1ncccc1C(=O)Cl>>COc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)/C=C/c4ccc(NC(=O)c5cccnc5C)nc4)c3Cl)cccc2n1C,,ClCCl,,CCN(CC)CC,Cl,test
US04596819,CC(C)(C)[C@H](N)C(=O)[O-].CC(C)CC(OC[C@@H]1CCCN1C(=O)OCc1ccccc1)C(=O)O>>CC(C)CC(OC[C@@H]1CCCN1C(=O)OCc1ccccc1)C(=O)NCC(=O)OC(C)(C)C,,CO,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US07659294B2,COCCN(CCOC)S(F)(F)F.O[C@H]1CC[C@@H](c2ccc(Br)cc2)C1>>F[C@@H]1CC[C@@H](c2ccc(Br)cc2)C1,,ClCCl,,O=C([O-])O.[Na+],,test
US05506089,BrCCCCBr.C(=Cc1ccncc1)c1ccccc1>>BrCCCC[n+]1ccc(C=Cc2ccccc2)cc1.[Br-],,CCOC(C)=O,,,,test
US20060025459A1,CCOC(=O)c1cc(N)c2[nH]cc(CC)c2c1.O=S(=O)(Cl)CCCCCl>>CCOC(=O)c1cc(NS(=O)(=O)CCCCCl)c2[nH]cc(CC)c2c1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,c1ccncc1,,test
US20130137691A1,CC(C)(C)OC(=O)CC[C@@H]1CC[C@@H](c2ccc(C(=O)Nc3nc(Cc4ccccc4)no3)cc2)CC1>>O=C(O)CC[C@@H]1CC[C@@H](c2ccc(C(=O)Nc3nc(Cc4ccccc4)no3)cc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070142362A1,CCC(C)(C)C(=O)N(C)OC.Cl[Mg]Cc1ccccc1>>CCC(C)(C)C(=O)Cc1ccccc1,,C1CCOC1,,,,test
US20030105095A1,BrBr.CC(C)(C)C(=O)Oc1ccccc1O>>CC(C)(C)C(=O)Oc1cc(Br)ccc1O,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US05272163,CC(O)(C(=O)O)C(F)(F)F.Nc1ccc(S(=O)(=O)c2ccccc2)c(F)c1>>CC(O)(C(=O)Nc1ccc(S(=O)(=O)c2ccccc2)c(F)c1)C(F)(F)F,,CC(=O)N(C)C,,O,O=S(Cl)Cl,test
US05994345,CC(=O)Cl.OCCc1ccc2ccccc2c1Br>>CC(=O)OCCc1ccc2ccccc2c1Br,,ClCCl,,CCN(CC)CC,,test
US20050261279A1,CCI.O=Cc1ccccc1O>>CCOc1cccc(C=O)c1,,CC(C)=O,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US20130237537A1,Nc1cccc(C(F)(F)F)c1.O=C(O)c1cccc(Br)c1>>O=C(Nc1cccc(C(F)(F)F)c1)c1cccc(Br)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150284408A1,Cc1ccc(CNC2(C(N)=O)CCN(C(=O)OC(C)(C)C)CC2)cc1[N+](=O)[O-]>>Cc1ccc(CNC2(C(N)=O)CCNCC2)cc1[N+](=O)[O-],,C1COCCO1,ClCCl,Cl,,test
US20100234365A1,COc1ccc(I)cc1.O=C1NCC(c2cccc(C(F)(F)F)c2)N1c1ccc(Oc2ccc(Cl)cc2)cc1>>COc1ccc(N2CC(c3cccc(C(F)(F)F)c3)N(c3ccc(Oc4ccc(Cl)cc4)cc3)C2=O)cc1,[Cu]I,,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US04239761,CCN(CC)C(=O)NC.ClCCCN1CCOCC1>>CCN(CC)C(=O)N(C)CCCN1CCOCC1.Cl,,C1COCCO1,,,,test
US05856503,C=CCN(C)CCCCCCOc1ccc2c(c1)CCN=C2c1ccc(Br)cc1>>C=CCN(C)CCCCCCOc1ccc2c(c1)CCNC2c1ccc(Br)cc1,,CCO,,[BH4-].[Na+],,test
US20060135551A1,CCOC(=O)N1c2c(c(C)nn2C)C(NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1CC.COC(=O)Cl>>CCOC(=O)N1c2c(c(C)nn2C)C(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(=O)OC)CC1CC,,O,,C1CCOC1,O=C([O-])[O-].[K+].[K+],test
US20100227858A1,C[C@H]1CNC[C@@H](C)O1.C[C@H]1COCCN1c1cc(CS(C)(=O)=O)nc(Cl)n1>>C[C@H]1CN(c2nc(CS(C)(=O)=O)cc(N3CCOC[C@@H]3C)n2)C[C@@H](C)O1,,CC(=O)N(C)C,,O=C([O-])[O-].[Na+].[Na+],,test
US05652237,CNc1ccccc1I.COC(=O)c1ccccc1N=C=O>>CN(c1nc2ccccc2c(=O)o1)c1ccccc1I,,Cc1ccccc1,,CCN(C(C)C)C(C)C,Cl,test
US20130029962A1,NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1.O=C(Nc1ccc(N2CC[C@H](O)C2)nc1)Oc1ccccc1>>O=C(NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)Nc1ccc(N2CC[C@H](O)C2)nc1,,CS(C)=O,O,CCN(CC)CC,,test
US20120202828A1,CCN1C(=O)[C@@H]2[C@@H](C(F)(F)F)OC[C@]2(c2cc(NC(=O)c3cnc(C(F)F)cn3)ccc2F)N=C1NC(=O)OC(C)(C)C>>CCN1C(=O)[C@@H]2[C@@H](C(F)(F)F)OC[C@]2(c2cc(NC(=O)c3cnc(C(F)F)cn3)ccc2F)N=C1N,,ClCCl,,O=C(O)C(F)(F)F,,test
US05756507,COc1ccc(-c2[nH]c3ccccc3c2CCNC(=O)Cc2ccc([N+](=O)[O-])cc2)cc1OC>>COc1ccc(-c2[nH]c3ccccc3c2CCNCCc2ccc([N+](=O)[O-])cc2)cc1OC,,C1CCOC1,,B,,test
US20120202853A1,COc1ccc(-c2nn(C)c(CCO[Si](C)(C)C(C)(C)C)c2-c2c(C)noc2C)cc1>>Cc1noc(C)c1-c1c(-c2ccc(O)cc2)nn(C)c1CCO,,ClCCl,,FB(F)F,,test
US20060089370A1,COc1ccc(C(C)N)cc1.O=[N+]([O-])c1cc2c(Cl)ncnc2s1>>COc1ccc(C(C)Nc2ncnc3sc([N+](=O)[O-])cc23)cc1,,CN(C)C=O,O,CCN(CC)CC,Cl,test
US06875884B1,CCI.O=C1c2ccccc2C(=O)N1CCCNCCc1ccc(Cl)cc1>>CCN(CCCN1C(=O)c2ccccc2C1=O)CCc1ccc(Cl)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060079526A1,N#CBr.NNC(=O)c1ccc(Oc2cccnc2)cc1>>Br.Nc1nnc(-c2ccc(Oc3cccnc3)cc2)o1,,C1CCOC1,,,,test
US20160221990A1,Clc1cc(/C=C/c2ccc(N3CCNCC3)cc2)cc(Cn2ccnc2)c1.O=S(=O)(Cl)c1cccc(OC(F)(F)F)c1>>O=S(=O)(c1cccc(OC(F)(F)F)c1)N1CCN(c2ccc(/C=C/c3cc(Cl)cc(Cn4ccnc4)c3)cc2)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20110053907A1,CC(C)(C)OC(=O)N1CCC(O)CC1.Clc1nc(Cl)nc(N2CCOCC2)n1>>CC(C)(C)OC(=O)N1CCC(Oc2nc(Cl)nc(N3CCOCC3)n2)CC1,,C1CCOC1,,[H-].[Na+],,test
US20020115826A1,O=C1CCC(=O)N1Br.OCCc1ccc2ccccc2c1>>BrCCc1ccc2ccccc2c1,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090253687A1,CCOC(=O)C(F)(F)F.COc1cc(C(C)=O)cc2c1OCC(=O)N2>>COc1cc(C(=O)CC(=O)C(F)(F)F)cc2c1OCC(=O)N2,,CCOCC,,,,test
US20080261941A1,NC(=O)c1ccccn1.O=C(Cl)Oc1ccccc1>>O=C(NC(=O)c1ccccn1)Oc1ccccc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20150031730A1,Cn1oc(=O)nc1/C(=N\OCc1csc(N)n1)c1ccccc1.O=C(Cl)Cc1ccc(Cl)cc1>>Cn1oc(=O)nc1/C(=N\OCc1csc(NC(=O)Cc2ccc(Cl)cc2)n1)c1ccccc1,,ClCCl,,c1ccncc1,,test
US20090253669A1,COc1cc(C)c(S(=O)(=O)N(C)CCOCC(=O)N2CCC(c3ccncc3)(N(C)C(=O)OC(C)(C)C)CC2)c(C)c1.Cl>>CNC1(c2ccncc2)CCN(C(=O)COCCN(C)S(=O)(=O)c2c(C)cc(OC)cc2C)CC1.Cl,,CCOC(C)=O,,C1COCCO1,,test
US20160168137A1,N#Cc1csc(Br)n1.OB(O)c1cccc2ccccc12>>N#Cc1csc(-c2cccc3ccccc23)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US05216167,CCOC(=O)c1ccc(CC(=O)NC(C(=O)OCC)c2ccccc2N2CCCCC2)cc1OCC>>CCOc1cc(CC(=O)NC(C(=O)O)c2ccccc2N2CCCCC2)ccc1C(=O)O,,CCO,,Cl,[Na+].[OH-],test
US20110251178A1,C#CCCOCc1ccccc1.O=C(Cl)c1ccc(F)cc1>>O=C(C#CCCOCc1ccccc1)c1ccc(F)cc1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20070254865A1,O=C(NC1CC2(CCC1c1cc(F)c(F)cc1F)OCCO2)OCc1ccccc1>>O=C(N[C@H]1CC2(CC[C@@H]1c1cc(F)c(F)cc1F)OCCO2)OCc1ccccc1,,CCCCCCC,,CC(C)O,,test
US20080207891A1,CCCCc1nccn1-c1nc(Cl)nc2nc[nH]c12.Cc1ccc(C(=O)OC[C@H]2O[C@H](Cl)C[C@@H]2OC(=O)c2ccc(C)cc2)cc1>>CCCCc1nccn1-c1nc(Cl)nc2c1ncn2[C@H]1C[C@H](OC(=O)c2ccc(C)cc2)[C@@H](COC(=O)c2ccc(C)cc2)O1,,CC#N,ClCCl,[Na],,test
US05637579,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.C[C@@]1(C=O)S[C@@H]2CC(=O)N2[C@H]1C(=O)OC(c1ccccc1)c1ccccc1>>CCOC(=O)/C=C/[C@]1(C)S[C@@H]2CC(=O)N2[C@H]1C(=O)OC(c1ccccc1)c1ccccc1,,C1CCOC1,,,,test
US20090306133A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CNC(=O)c2cc(-c3ccc(CNC(=O)OCC4c5ccccc5-c5ccccc54)cc3)nc3ccccc23)CC1.CS(C)=O>>CC(=O)O.CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CNC(=O)c2cc(-c3ccc(CN)cc3)nc3ccccc23)CC1,,ClCCl,,C1CCNCC1,,test
US20040266777A1,C=CCN=C=S.Nc1ccc2ncc(-c3ccccc3)nc2n1>>C=CCNC(=S)Nc1ccc2ncc(-c3ccccc3)nc2n1,,CN(C)C=O,,[H-].[Na+],,test
US20150329535A1,C=CCCc1nc2cc(CO)ccc2o1>>C=CCCc1nc2cc(C=O)ccc2o1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20140213554A1,Cc1[nH]nc(C=O)c1Cl.Nc1cnc2[nH]c(-c3ccc(F)cc3)cc2c1>>Cc1[nH]nc(CNc2cnc3[nH]c(-c4ccc(F)cc4)cc3c2)c1Cl,,C1CCOC1,,[BH4-].[Na+],,test
US20160159774A1,CC(C)(C)[Si](C)(C)OCC=O.O=[N+]([O-])c1ccc2c(c1)CNC2>>CC(C)(C)[Si](C)(C)OCCN1Cc2ccc([N+](=O)[O-])cc2C1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US06172066B2,NCCN.O=C1CCC(c2ccccc2)(c2ccccc2)CC1>>NCCNC1CCC(c2ccccc2)(c2ccccc2)CC1,Cc1ccc(S(=O)(=O)O)cc1,c1ccccc1,,,,test
US06118020,CCCCCCCCCCCCO.CCOC(=O)C(C)N(C)C>>CCCCCCCCCCCCOC(=O)C(C)N(C)C,,CCO,,C[O-].[Na+],,test
US20150322056A1,Cc1cc(F)ccn1.Ic1cc[nH]n1>>Cc1cc(-n2ccc(I)n2)ccn1,,CS(C)=O,,[H-].[Na+],,test
US20150119380A1,O=c1ccc2ccc(C#CCCO)cc2o1>>O=c1ccc2ccc(CCCCO)cc2o1,[Pd],CO,,,,test
US20100105700A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@]12CC[C@H]3[C@@H](CC=C4NC(=O)CC[C@@]43C)[C@@H]1CCC2=O>>CC(C)(C)OC(=O)N1C(=O)CC[C@@]2(C)C1=CC[C@H]1[C@@H]3CCC(=O)[C@@]3(C)CC[C@@H]12,CN(C)c1ccncc1,ClCCl,,O,,test
US20080234318A1,CN.CN1CCN(c2cccc3nc(CN(C)[C@H]4CCCc5cccnc54)c(C=O)n23)CC1>>CNCc1c(CN(C)[C@H]2CCCc3cccnc32)nc2cccc(N3CCN(C)CC3)n12,,CC(Cl)Cl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090181967A1,Fc1ccc(N2CCNCC2)c(F)c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCN(c2ccc(F)cc2F)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20080153836A1,COC(=O)c1cc(-c2ccnnc2)c(C(C)C)cc1N.CS(=O)(=O)NN.O=C(Cl)Oc1ccc(Cl)cc1>>CC(C)c1cc2[nH]c(=O)n(NS(C)(=O)=O)c(=O)c2cc1-c1ccnnc1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US04161529,CCOC(=O)CBr.c1ccc(Oc2ccc(C3CCCN3)cc2)cc1>>CCOC(=O)CN1CCCC1c1ccc(Oc2ccccc2)cc1,,c1ccccc1,,,,test
US20140163035A1,CON=C1COc2c[n+]([O-])ccc21.O=P(Cl)(Cl)Cl>>CON=C1COc2c1ccnc2Cl,,ClCCl,,,,test
US20060069110A1,CN(C)C=O.CNc1nc(-c2ccccc2)ncc1C(=O)O>>CNc1nc(-c2ccccc2)ncc1C(N)=O,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US05716905,Cc1c([N+](=O)[O-])ccc2c1C(=O)NS2(=O)=O>>Cc1c(N)ccc2c1C(=O)NS2(=O)=O,[Pd],O,,[H][H],,test
US05278175,CCc1ncnc(Cl)c1F.O=C(Cn1cncn1)c1ccc(F)cc1F>>CC(c1ncnc(Cl)c1F)C(O)(Cn1cncn1)c1ccc(F)cc1F,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US06693137B1,CN(C)CCCl.Cc1ccccc1.Oc1ccc(Br)cc1>>CN(C)CCCOc1ccc(Br)cc1,,[Na+],[OH-],Cl,,test
US20070054903A1,CC1(C)OB(c2ccc3cc(NC(=O)c4ccsc4)ccc3c2)OC1(C)C.Cc1c(Br)cccc1C(N)=O>>Cc1c(C(N)=O)cccc1-c1ccc2cc(NC(=O)c3ccsc3)ccc2c1,[Pd],O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20150376130A1,CC=O.CCOC(=O)c1ccc(C(F)(F)F)nc1N>>CCNc1nc(C(F)(F)F)ccc1C(=O)OCC,,ClCCl,,O=C(O)C(F)(F)F,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20070287725A1,CCOCC(=O)Cl.Nc1c(Cl)nc2ccccc2c1NCc1cc(-c2ccc(F)cc2)no1>>CCOCC(=O)Nc1c(Cl)nc2ccccc2c1NCc1cc(-c2ccc(F)cc2)no1,,ClCCl,,CCN(CC)CC,,test
US05545755,CCCNC1CCc2cccc(OC)c2C1.O=C1c2ccccc2S(=O)(=O)N1CCCI>>CCCN(CCCN1C(=O)c2ccccc2S1(=O)=O)C1CCc2cccc(OC)c2C1,,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20030069419A1,CC(C)(C)Oc1ccc(CCCCI)cc1.c1c[nH]nn1>>CC(C)(C)Oc1ccc(CCCCn2ccnn2)cc1,,CCC(C)(C)O,,[Na+].[OH-],,test
US20150329538A1,CCOC(=O)CC(=O)C(C)(C)NC(=O)OC(C)(C)C.Cc1nc2cccc(C(=O)CBr)c2nc1NC(C)(C)C>>CCOC(=O)C(CC(=O)c1cccc2nc(C)c(NC(C)(C)C)nc12)C(=O)C(C)(C)NC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US04691023,CC(=O)NCCS.CS(SCCN)=C(O)O>>CC(=O)NCCSSCCN,,CO,,CCN(CC)CC,Cl,test
US06355810B1,CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(=O)O>>CC(C)c1c(C(=O)O)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1,,C1CCOC1,O,Cl,[Na+].[OH-],test
US05137905,C#CC(C)N1CCNC1=O.CI>>C#CC(C)N1CCN(C)C1=O,,C1CCOC1,CO,CC(=O)O,[H-].[Na+],test
US07473787B2,CCc1ccc(C(=O)Cl)cc1.O=C(c1cccs1)N(CC1C2CNCC21)c1ccc(N2CCOCC2)c(F)c1>>CCc1ccc(C(=O)N2CC3C(C2)C3CN(C(=O)c2cccs2)c2ccc(N3CCOCC3)c(F)c2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150191465A1,C[C@H](N)c1nc2ccn(C)c2cc1N(C)C1CN(C(=O)OC(C)(C)C)C1.Cc1nc(N)nc(Cl)c1C#N>>Cc1nc(N)nc(N[C@@H](C)c2nc3ccn(C)c3cc2N(C)C2CN(C(=O)OC(C)(C)C)C2)c1C#N,,CS(C)=O,,CCN(CC)CC,,test
US20050014940A1,COC1C2CN(Cc3ccccc3)CC(CN1C(=O)OCc1ccccc1)O2>>c1ccc(CN2CC3CNCC(C2)O3)cc1,[Pd],CO,,,,test
US20150284370A1,C#CCBr.CN1CCCNCC1>>C#CCN1CCCN(C)CC1,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04668703,CC(=O)OC(C)=O.N[C@@H](CCC(=O)O)C(=O)O>>CC(=O)C1CCC(=O)N1C(C)=O,CN(C)c1ccncc1,,,CCN(CC)CC,,test
US05736534,COc1cc2ncnc(Cl)c2cc1OC.Cc1c(F)ccc2c1NCC2.Cl>>COc1cc2ncnc(N3CCc4ccc(F)c(C)c43)c2cc1OC.Cl,,CN1CCCC1=O,,,,test
US05118534,CC#N.CCCCCCCCSCCN.O=C=O>>CCCCCCCCSCCN.NC(=O)O,,CC#N,,,,test
US20100130446A1,O=S(=O)(c1ccc(C(CC2CCOCC2)c2ccc(-c3ccc(O)cn3)[nH]2)cc1)C1CC1.OCC1CC1>>O=S(=O)(c1ccc(C(CC2CCOCC2)c2ccc(-c3ccc(OCC4CC4)cn3)[nH]2)cc1)C1CC1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20070219230A1,CSc1c(C)[nH]c2c(N3CCc4ccccc4C3)nccc12.Cl>>CSc1c(C)[nH]c2c(N3CCc4ccccc4C3)nccc12.Cl,,CCOC(C)=O,,,,test
US05958931,CC(=O)CC(C)=O.COc1ccc(C=O)cc1.NC(N)=S>>COc1ccc(C2NC(=S)NC(C)=C2C(C)=O)cc1,Cl,CCO,,,,test
US05527818,CN(C)S(=O)(=O)Cl.O=S(=O)(Oc1cccc(C(F)(F)F)c1)c1nc[nH]n1>>CN(C)S(=O)(=O)n1cnc(S(=O)(=O)Oc2cccc(C(F)(F)F)c2)n1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20100069630A1,CN1CCC(NC(=O)/C(=C/c2ccc(C(=O)NOC3CCCCO3)cc2)COc2cccc3ccccc23)CC1>>CN1CCC(NC(=O)/C(=C/c2ccc(C(=O)NO)cc2)COc2cccc3ccccc23)CC1,,CO,,O=C(O)C(F)(F)F,,test
US20040157817A1,CCCS(=O)(=O)Cl.NC1CCCCC1O>>CC(C)S(=O)(=O)NC1CCCCC1O,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20150284396A1,CCCCc1nc(N)c2c(n1)c(C#CCCO)c(C)n2COCc1ccccc1>>CCCCc1nc(N)c2c(n1)c(CCCCO)c(C)n2COCc1ccccc1,[Pd],CCO,,,,test
US20160075720A1,CCOCCO.COc1ccc(CNc2cc(Cl)nc(Cl)n2)cc1>>COCCOc1nc(Cl)cc(NCc2ccc(OC)cc2)n1,,C1CCOC1,,[H-].[Na+],,test
US20100240623A1,CCCCOc1nc(N)c2[nH]c(=O)n(CCCN(Cc3cccc(CC(=O)OC)c3)C(=O)CCC(=O)OC(C)(C)C)c2n1>>CCCCOc1nc(N)c2[nH]c(=O)n(CCCN(Cc3cccc(CC(=O)OC)c3)C(=O)CCC(=O)O)c2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060247266A1,c1cc2c3c(cncc3c1)CCN2C1CCC2(CC1)OCCO2>>O=C1CCC(N2CCc3cncc4cccc2c34)CC1,,Cl,,[Na+].[OH-],,test
US20140221333A1,CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)[C@@H](c2nc(Br)c3c(Cl)nccn23)C1.COc1ccc(CN)c(OC)c1>>COc1ccc(CNc2nccn3c([C@H]4CN(C(=O)OC(C)(C)C)CCN4C(=O)OC(C)(C)C)nc(Br)c23)c(OC)c1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20100076203A1,CCOC(=O)C(C#N)(CC(=O)OC1CC(C)CCC1C(C)C)NC(=O)OC(C)(C)C.OO>>CCOC(=O)C(CC(=O)OC1CC(C)CCC1C(C)C)(NC(=O)OC(C)(C)C)C(N)=O,,CC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20150005293A1,CC(C)CC(CN)c1ccc(C(F)(F)F)cc1.O=C(O)c1cn(-c2ncccn2)nc1Cl>>CC(C)CC(CNC(=O)c1cn(-c2ncccn2)nc1Cl)c1ccc(C(F)(F)F)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20070149577A1,CON.COc1cc(C=O)ccc1-c1cc(F)ccc1OC>>CON=Cc1ccc(-c2cc(F)ccc2OC)c(OC)c1,,c1ccncc1,,Cl,,test
US09388133B2,CN(Cc1cc(C2=CCCCC2)n(S(=O)(=O)c2cccc(O)c2)c1)C(=O)OC(C)(C)C.O=C(CBr)NC1CC1>>CN(Cc1cc(C2=CCCCC2)n(S(=O)(=O)c2cccc(OCC(=O)NC3CC3)c2)c1)C(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020178811A1,O=C([O-])C(O)C(O)C(=O)O.O=C([O-])O.[K+].[Na+]>>O=C([O-])C(O)C(O)C(=O)[O-].O=C=O.[K+].[Na+],,O,,,,test
US20100113441A1,CC(C)(C)OC(=O)NCCN.Clc1ccc(-c2cc3nccn3c(Cl)n2)c(Cl)c1>>CC(C)(C)OC(=O)NCCNc1nc(-c2ccc(Cl)cc2Cl)cc2nccn12,,CS(C)=O,O,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20030045581A1,NNC(=S)NC1CC2C=CC1C2.O=Cc1ccccn1>>S=C(NN=Cc1ccccn1)NC1CC2C=CC1C2,,CCO,,CC(=O)O,,test
US20020042427A1,O=C1Cc2cc(-c3ccccc3)ccc2N1.O=Cc1[nH]cc2c1CCNC2=O>>O=C1Nc2ccc(-c3ccccc3)cc2C1=Cc1[nH]cc2c1CCNC2=O,,CCO,,C1CCNCC1,,test
US20040259896A1,C=C(CI)CN(Cc1ccccc1)[C@@H](CC(=O)OC(C)(C)C)C(=O)OCc1ccccc1>>C=C1C[C@H](C(=O)OC(C)(C)C)[C@@H](C(=O)OCc2ccccc2)N(Cc2ccccc2)C1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20020151715A1,CC(=O)O.CCOC(=O)C[N+](=O)[O-].CCOC(OCC)OCC.Nc1ccc(SC(F)(F)F)c(Cl)c1>>OCc1cn(-c2ccc(SC(F)(F)F)c(Cl)c2)cn1,[Fe],,,,,test
US20050137202A1,CSc1cnc(N)c(C#CCO)n1.Fc1ccc(CBr)cc1>>CSc1cnc2c(cc(C=O)n2Cc2ccc(F)cc2)n1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20020013466A1,COC(=O)CBr.Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3ccc(O)cc3)c(Cl)cc2F)c1=O>>COC(=O)COc1ccc(Oc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2Cl)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100240702A1,C=C(C)n1c(=O)n(Cc2cn(C)c3cccc(C)c23)c2cc(C)c(C)cc21>>Cc1cc2[nH]c(=O)n(Cc3cn(C)c4cccc(C)c34)c2cc1C,,CO,ClCCl,Cl,O,test
US20130165440A1,C=Cc1cc(Nc2nnc(-c3ccc(C(=O)OC)cc3)c3ccccc23)cc(C(F)(F)F)c1>>CCc1cc(Nc2nnc(-c3ccc(C(=O)OC)cc3)c3ccccc23)cc(C(F)(F)F)c1,[Pd],CO,,,,test
US20040044201A1,CC(C)C[C@H](NC(=O)c1cc2ccccc2o1)C(=O)N[C@H]1CC[C@@H](C)N(S(=O)(=O)c2ccccn2)C[C@@H]1O>>CC(C)C[C@H](NC(=O)c1cc2ccccc2o1)C(=O)N[C@H]1CC[C@@H](C)N(S(=O)(=O)c2ccccn2)CC1=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20100069381A1,Nc1cc(-c2nnc(CCc3cccc(F)c3)o2)ccn1.O=C(Cl)OCc1ccccc1>>O=C(Nc1cc(-c2nnc(CCc3cccc(F)c3)o2)ccn1)OCc1ccccc1,CN(C)c1ccncc1,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20110021514A1,COC(=O)C1CCc2c(ccc[n+]2[O-])C1.C[Si](C)(C)C#N>>COC(=O)C1CCc2nc(C#N)ccc2C1,,CC#N,ClCCl,CCN(CC)CC,O=C([O-])[O-].[Na+].[Na+],test
US20100130492A1,CC(C)Cn1c(N2CCN[C@H](C)C2)nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc21.CS(=O)(=O)Cl>>CC(C)Cn1c(N2CCN(S(C)(=O)=O)[C@H](C)C2)nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc21,,C1CCOC1,,CCN(CC)CC,,test
US04153721,CCOC(=O)Cc1ccc(-c2ccc3oc(C(=O)OCC)c(C)c3c2)cc1>>Cc1coc2ccc(-c3ccc(CC(=O)O)cc3)cc12,,CC(=O)O,,Br,,test
US20060264464A1,CC[C@H](NC(=O)OC(C)(C)C)C(O)c1nc(-c2ccccc2)no1>>CC[C@H](N)C(O)c1nc(-c2ccccc2)no1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05457128,CC(O)CNCC(C)O.CCCOC(=O)c1ccc(N)cc1.COC(=O)c1ccc(N)cc1>>NC[C@@H]1CC[C@@H](C(=O)Oc2ccc(CCC(=O)O)cc2)CC1,,O,,,,test
US08022075B2,CN(C)/C=C/C(=O)c1ccc(-c2cn3cc(I)ccc3n2)cc1.NN>>Ic1ccc2nc(-c3ccc(-c4cc[nH]n4)cc3)cn2c1,,CCO,,O,,test
US05741781,CC(=O)SC(Cc1ccc(O)cc1)C(=O)NCC(=O)N1C(c2ccccc2)CC[C@H]1C(=O)O>>O=C(NCC(=O)N1C(c2ccccc2)CC[C@H]1C(=O)O)C(S)Cc1ccc(O)cc1,,CO,,[Na+].[OH-],,test
US20070219198A1,C[C@@H]1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc(N2CCCC2C(=O)OC(C)(C)C)s1>>C[C@@H]1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc(N2CCCC2C(=O)O)s1,,ClCCl,,CC#N,O,test
US20080009492A1,CC(=O)Cl.CC(C)OC(=O)Nc1cnc2[nH]c(-c3cccc(N)c3)nc2c1>>CC(=O)Nc1cccc(-c2nc3cc(NC(=O)OC(C)C)cnc3[nH]2)c1,,c1ccncc1,,,,test
US20040132769A1,BrBr.Nc1c(F)c(F)cc(F)c1F>>Nc1c(F)c(F)c(Br)c(F)c1F,,CO,,O=C([O-])O.[Na+],,test
US06242439B1,C[C@@H]1C(=O)N[C@H]1Cc1ccccc1.O=C=NCc1ccccc1>>C[C@@H]1C(=O)N(C(=O)NCc2ccccc2)[C@H]1Cc1ccccc1,,C1CCOC1,CCOC(C)=O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20040110749A1,Cn1nc(-c2ccccc2)c(CSC2=NOC(C)(C)C2)c1Cl.O=C(OO)c1cccc(Cl)c1>>Cn1nc(-c2ccccc2)c(CS(=O)C2=NOC(C)(C)C2)c1Cl,,ClC(Cl)Cl,,O,,test
US20080207654A1,CCCCc1nc(OC)n(-c2ccccc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nc(OC)n(-c2ccccc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20120309739A1,COc1nccc2c(-c3ccccc3)c(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)oc12>>NC1(c2ccc(-c3oc4c(=O)[nH]ccc4c3-c3ccccc3)cc2)CCC1,,CC#N,,C[Si](C)(C)Cl,[I-].[Na+],test
US20110201605A1,CC(C)OC(=O)Cl.Cc1cc(C2=CCNCC2)c2nc(NC3CCN(c4cc(C)ncn4)CC3)nn2c1>>Cc1cc(C2=CCN(C(=O)OC(C)C)CC2)c2nc(NC3CCN(c4cc(C)ncn4)CC3)nn2c1,,ClCCl,,,,test
US20070259891A1,CCOC(=O)C(C)(C)c1ccc([N+](=O)[O-])cc1[N+](=O)[O-]>>CC1(C)C(=O)Nc2cc(N)ccc21,[Pd],CO,,,,test
US20100063078A1,COc1ccc(CCC(=O)O)cc1Cl>>COc1cc2c(cc1Cl)CCC2=O,,O,,,,test
US04954162,Fc1ccc(C2(C3(SC(F)(F)F)CC3)CO2)c(F)c1.c1nc[nH]n1>>OC(Cn1cncn1)(c1ccc(F)cc1F)C1(SC(F)(F)F)CC1,,CCOC(C)=O,CN(C)C=O,,,test
US20150045339A1,CCCNc1nc(Nc2cccc(F)c2)ncc1-c1cc(CCO)no1.O=C1NC(=O)c2ccccc21>>CCCNc1nc(Nc2cccc(F)c2)ncc1-c1cc(CCN2C(=O)c3ccccc3C2=O)no1,,C1CCOC1,Cc1ccccc1,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050234029A1,Brc1cc(-c2c(-c3ccccn3)nc3ccccn23)ccn1.OB(O)c1ccc(Br)cc1>>Brc1ccc(-c2cc(-c3c(-c4ccccn4)nc4ccccn34)ccn2)cc1,,CO,ClCCl,,,test
US20090054407A1,CC(C)(C)OC(=O)n1c(-c2ccc(O)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21.O=S(=O)(Cl)c1ccccc1C(F)(F)F>>CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)c3ccccc3C(F)(F)F)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21,,CC#N,,CCN(CC)CC,,test
US05302720,Cc1cccc(-c2ccccc2)c1N.O=C(N=C=S)c1ccccc1>>Cc1cccc(-c2ccccc2)c1NC(=S)NC(=O)c1ccccc1,,ClCCl,,,,test
US20130005744A1,Clc1nccc(-c2ccccc2)n1.Cn1cc(B(O)O)cc(OCc2ccccc2)c1=O>>Cn1cc(-c2nccc(-c3ccccc3)n2)cc(OCc2ccccc2)c1=O,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,C1COCCO1,,[F-].[K+],,test
US04238494,CSc1[nH]cc(-c2ccccc2)c1[N+](=O)[O-].OO>>CS(=O)c1[nH]cc(-c2ccccc2)c1[N+](=O)[O-],,CC(=O)O,,,,test
US20150307497A1,CC(=O)c1ccc(F)c(O)c1.C[Mg]Br>>CC(C)(O)c1ccc(F)c(O)c1,,C1CCOC1,,CCOC(C)=O,Cl,test
US20050032871A1,Cc1[nH]c(C=O)c(CCC(=O)O)c1S(=O)(=O)c1ccc(Cl)cc1.O=C1Cc2cc(-c3ccccc3)ccc2N1>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(-c4ccccc4)cc32)c(CCC(=O)O)c1S(=O)(=O)c1ccc(Cl)cc1,,CCO,,C1CCNCC1,,test
US04650865,CCCCCCCCOS(=O)(=O)[O-].OCCN(CCO)CCO>>CCCCCCCCOCCNCC(O)O,,O,,CO,C[O-].[Na+],test
US05817691,N#Cc1c(-c2ccc(Cl)cc2)[nH]c(C(F)(F)F)c1Sc1ccc(Cl)c(Cl)c1.O=S(=O)([O-])O[O-]>>N#Cc1c(-c2ccc(Cl)cc2)[nH]c(C(F)(F)F)c1S(=O)(=O)c1ccc(Cl)c(Cl)c1,,CO,,O,,test
US20140045746A1,CCOC(=O)C1Cc2cc(OC)ncc2C1=O>>COc1cc2c(cn1)C(=O)CC2,,CS(C)=O,O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20020193385A1,CC1(C)COB(B2OCC(C)(C)CO2)OC1.Fc1ccc(Br)c(F)c1-c1cccnc1>>OB(O)c1ccc(F)c(-c2cccnc2)c1F,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20100113412A1,CCOC(=O)Cl.N=C(NO)c1ccc2nc(-c3ccc(F)cc3)cn2c1>>CCOC(=O)ONC(=N)c1ccc2nc(-c3ccc(F)cc3)cn2c1,,CN(C)C=O,,CCN(CC)CC,,test
US20070259888A1,CC(C)(C)OC(=O)N1CCCC(CO)C1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCC2CCCN(C(=O)OC(C)(C)C)C2)cc1,,c1ccncc1,,,,test
US20120077828A1,Clc1nc[nH]c2ncc(Br)c1-2.OCCN1CCOCC1>>Clc1ncnc2c1c(Br)cn2CCN1CCOCC1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120258946A1,CCOC(=O)C(C)c1ccc(N)c(F)c1.O=S(=O)(Cl)CCCCl>>CCOC(=O)C(C)c1ccc(NS(=O)(=O)CCCCl)c(F)c1,,ClCCl,,c1ccncc1,,test
US06174874B1,COC(=O)c1ccc(CC(Cc2ccc(C(F)(F)P(=O)(OC(C)(C)C)OC(C)(C)C)cc2)(C(=O)c2ccccc2)c2ccccc2)cc1>>O=C(O)c1ccc(CC(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)(C(=O)c2ccccc2)c2ccccc2)cc1,,C1CCOC1,,[Na+].[OH-],,test
US20070123527A1,N#CC=C(c1ccccc1)c1ccc2[nH]ccc2c1>>N#CCC(c1ccccc1)c1cccc2[nH]ccc12,,CC(C)O,,[BH4-].[Na+],,test
US20060189606A1,CCn1c(-c2ccc(O)c(NC(=O)CCl)c2)c(C#N)c2ccc(OC)cc21>>CCn1c(-c2ccc3c(c2)NC(=O)CO3)c(C#N)c2ccc(OC)cc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130274255A1,NN.O=C(c1ccc(Br)cc1)C1Cc2sccc2C1=O>>Brc1ccc(-c2n[nH]c3c2Cc2sccc2-3)cc1,,CCO,,CC(=O)O,O,test
US20130302679A1,C1CCC2=NCCCN2CC1.NC(=S)NC(N)=S.S=C=Nc1ccccc1N=C=S>>NC(=S)N(C(=S)Nc1ccccc1)c1ccccc1,,CCO,,CN1CCCC1=O,,test
US04594342,COc1ccc([C@@H]2Sc3cc(C)ccc3N(CCN(C)Cc3ccccc3)C(=O)[C@@H]2OC(C)=O)cc1.O=C(Cl)OCc1ccccc1>>COc1ccc([C@@H]2Sc3cc(C)ccc3N(CCN(C)C(=O)OCc3ccccc3)C(=O)[C@@H]2OC(C)=O)cc1,,c1ccccc1,,,,test
US20040009995A1,CC1(C)OBOC1(C)C.Cc1cccc(C(=O)OC(C)(C)C)c1I>>Cc1ccc(C(=O)OC(C)(C)C)c(B2OC(C)(C)C(C)(C)O2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,CCN(CC)CC,,test
US20110003787A1,CC[C@H]1CN=C(c2ccc(-c3cc(Oc4cnc(S(C)(=O)=O)cn4)cc(O[C@@H](C)COC)c3)[nH]2)O1>>CC[C@H]1CN=C(c2ccc(-c3cc(Oc4cnc(S(C)(=O)=O)cn4)cc(O[C@@H](C)CO)c3)[nH]2)O1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US04480100,Cl.Nc1ccccc1C(=O)c1ccccc1.O=[N+]([O-])c1cccnc1Cl>>Cl.O=C(c1ccccc1)c1ccccc1Nc1ncccc1[N+](=O)[O-],,ClCCl,,CCCCCC,,test
US05264605,CC(C)N(C(C)C)P(Cl)N(C(C)C)C(C)C.OCc1ccccc1CO>>CC(C)N(C(C)C)P1OCc2ccccc2CO1,,C1CCOC1,,,,test
US20130059834A1,Cc1nn(-c2cnc3c(n2)c(C(=O)NC(C)(C)CO)cn3COCC[Si](C)(C)C)c2ccc(Cl)cc12>>Cc1nn(-c2cnc3[nH]cc(C(=O)NC(C)(C)CO)c3n2)c2ccc(Cl)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100029687A1,COC(=O)c1cc(F)c(F)c(F)c1.C[C@H](c1cccc2ccccc12)N(CC1CNCCC1c1ccccc1)C(=O)OC(C)(C)C>>COC(=O)c1cc(F)c(N2CCC(c3ccccc3)C(CN(C(=O)OC(C)(C)C)[C@H](C)c3cccc4ccccc34)C2)c(F)c1,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20160016947A1,Cc1ccc([C@H]2C[C@@H]2COc2cc(N(Cc3nnc(C)s3)C(=O)OC(C)(C)C)c(=O)n(C)n2)nc1>>Cc1ccc([C@H]2C[C@@H]2COc2cc(NCc3nnc(C)s3)c(=O)n(C)n2)nc1,,O=C(O)C(F)(F)F,,,,test
US20130210825A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nn4c(/C=C/C(N)=O)cnc4cc3-c3ccccc3)cc2)CCC1>>NC(=O)/C=C/c1cnc2cc(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nn12,,C1COCCO1,Cl,,,test
US20160024103A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(CO)c(OC(C)C)cc12.CS(=O)(=O)Cl>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(COS(C)(=O)=O)c(OC(C)C)cc12,CN(C)c1ccncc1,ClCCl,O,,,test
US04543361,CC(C)(C)OC(=O)OC(C)(C)C.CN(C)C=O.O=C(c1ccc2c(c1)OCO2)c1ccc(CCc2ccccc2)[nH]1>>CC(C)(C)OC(=O)n1c(CCc2ccccc2)ccc1C(=O)c1ccc2c(c1)OCO2.c1cc[nH]c1,,CN(C)C=O,,[H-].[Na+],,test
US20080176309A1,NNc1ccccc1[N+](=O)[O-].O=C1Nc2ccc(S(=O)(=O)NCc3ccco3)cc2C1=O>>O=C1Nc2ccc(S(=O)(=O)NCc3ccco3)cc2C1=NNc1ccccc1[N+](=O)[O-],Cl,CCO,,,,test
US20150111877A1,Cc1cccc(S(=O)(=O)N2CC(NC(=O)OC(C)(C)C)COc3ncc(NC(=O)c4c(Cl)cccc4Cl)cc32)c1>>Cc1cccc(S(=O)(=O)N2CC(N)COc3ncc(NC(=O)c4c(Cl)cccc4Cl)cc32)c1,,C1COCCO1,,Cl,,test
US20100249124A1,COc1ccc(Cl)c(C(C)C(O)(c2ccc3oc(=O)n(C)c3c2)C(F)(F)F)c1>>CC(c1cc(O)ccc1Cl)C(O)(c1ccc2oc(=O)n(C)c2c1)C(F)(F)F,,ClCCl,,O=C([O-])O.[Na+],,test
US04699913,NNC(=S)c1ccc(Cl)cc1.O=Cc1cccnc1>>Clc1ccc(C2=NNC(c3cccnc3)S2)cc1,,CCO,,,,test
US20110053940A1,CC(C)(C)[Si](C)(C)Cl.OCc1cc(Br)cc(Cl)c1Cl>>CC(C)(C)[Si](C)(C)OCc1cc(Br)cc(Cl)c1Cl,,CCOCC,,CN(C)C=O,c1c[nH]cn1,test
US20040053986A1,COc1ccc(OC(CCCN2CC3CN(C(=O)OC(C)(C)C)CC3C2)c2ccc(C#N)cc2)cc1OC>>COc1ccc(OC(CCCN2CC3CNCC3C2)c2ccc(C#N)cc2)cc1OC,,CCOC(C)=O,,Cl,,test
US05763439,COC(=O)c1c(Cl)cnn(C(C)(C)C)c1=O.NCc1ccncc1>>COC(=O)c1c(NCc2ccncc2)cnn(C(C)(C)C)c1=O,,CCN(CC)CC,,CCO,,test
US05972965,CC(C)(C)[Si](Oc1cccc2c1CCC[C@H]2N1CCC[C@@H]1c1nc(-c2ccccc2)c(-c2ccccc2)o1)(c1ccccc1)c1ccccc1.CCOC(C)=O>>CCOC(=O)COc1cccc2c1CCC[C@H]2N1CCC[C@@H]1c1nc(-c2ccccc2)c(-c2ccccc2)o1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06403584B1,COB(OC)OC.COc1cccc(N(C)C)c1>>COc1cccc(N(C)C)c1B(O)O,,C1CCOC1,,[Li]CCCC,,test
US04118561,ClCc1ccccc1.Nc1nc(N)c2c(ccc3[nH]ccc32)n1>>Nc1nc(N)c2c(ccc3c2ccn3Cc2ccccc2)n1,,CC(=O)O,,CN(C)C=O,[H-].[Na+],test
US20100179211A1,CC(C)(C)OC(=O)N1CCC(O)(c2cc(Cl)cc(Cl)c2)C1.CCN(CC)S(F)(F)F>>CC(C)(C)OC(=O)N1CCC(F)(c2cc(Cl)cc(Cl)c2)C1,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20040214798A1,CC(=O)Oc1cc([N+](=O)[O-])ccc1C.O=C1CCC(=O)N1Br>>CC(=O)Oc1cc([N+](=O)[O-])ccc1CBr,,ClC(Cl)(Cl)Cl,ClCCl,,,test
US20150045274A1,C/C=C/C(=O)C1C(C)C=CCC1(C)C.O=C([O-])CS.[NH4+]>>CC(CC(=O)C1C(C)C=CCC1(C)C)SCC(=O)[O-].[NH4+],,O,,,,test
US20090023761A1,C[C@H](N)c1cc2cccc(Cl)c2nc1-c1ccccn1.Nc1ncc(Cl)c(Cl)n1>>C[C@H](Nc1nc(N)ncc1Cl)c1cc2cccc(Cl)c2nc1-c1ccccn1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20050148604A1,CN1CCN(c2ccc(-c3nc4c(c(C5CCCCC5)nn4C)c(=O)[nH]3)c(OC(F)F)c2)CC1.CS(=O)(=O)O>>CN1CCN(c2ccc(-c3nc4c(c(C5CCCCC5)nn4C)c(=O)[nH]3)c(OC(F)F)c2)CC1.CS(=O)(=O)O,,CO,,,,test
US20140038999A1,COC(=O)c1c(I)ccnc1C.OB(O)c1ccc(Br)c(F)c1F>>COC(=O)c1c(-c2ccc(Br)c(F)c2F)ccnc1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US03935314,Cl.Cl.Cl.c1ccc2[nH]c(NC3=NCCN3)nc2c1>>Cl.Clc1cc2nc(N3C=NCC3)[nH]c2cc1Cl,,Cl,,OO,,test
US20140179698A1,Brc1cncc(-c2cnco2)c1.Oc1ccccn1>>O=c1ccccn1-c1cncc(-c2cnco2)c1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US04234517,C=C(C)C.O=C(Cl)CCC(Cl)(Cl)Cl>>CC1(C)CC(=O)C1CC(Cl)(Cl)Cl,,C1CCCCC1,,CCN(CC)CC,,test
US20030144333A1,CCOC(=O)C(=O)c1cc(Cl)sc1Cl>>O=C(O)C(=O)c1cc(Cl)sc1Cl,,O,,Cl,[Na+].[OH-],test
US20100069374A1,COCOc1cc2c(cc1[N+](=O)[O-])C(O)=C(Br)C(C)(C)O2>>COCOc1cc2c(cc1[N+](=O)[O-])C1OC1C(C)(C)O2,,C1COCCO1,,O,[Na+].[OH-],test
US20160016981A1,CCCCCCCCCCCCCCCCNC.CCOP(=O)(CCCBr)OCC>>Br.CCCCCCCCCCCCCCCCN(C)CCCP(=O)(OCC)OCC,,CCOCC,,CCN(C(C)C)C(C)C,,test
US20120010190A1,COc1ccc(C(=O)C[C@@H](c2ccc(Br)cc2)c2ccccc2C)cn1>>Cc1ccccc1[C@@H](CC(=O)c1ccc(=O)[nH]c1)c1ccc(Br)cc1,,C1COCCO1,,Cl,,test
US20110172237A1,O=C(CBr)Nc1cc(F)cc(F)c1.O=C(O[C@H]1CN2CCC1CC2)C1(c2ccccc2)CCCCCC1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C1(c3ccccc3)CCCCCC1)C2)Nc1cc(F)cc(F)c1.[Br-],,CC#N,,,,test
US20160168090A1,O=C(NCC1(O)CCC(F)(F)CC1)c1c[nH]c2nccc(Cl)c12.OCC1COC1>>O=C(NCC1(O)CCC(F)(F)CC1)c1cn(CC2COC2)c2nccc(Cl)c12,,Cc1ccccc1,,CCCCP(=CC#N)(CCCC)CCCC,,test
US20100254916A1,Cc1noc(C)c1Cn1cc(N2C(=O)NC(C)(C)C2=O)cn1.N#Cc1ccc(CCl)cc1>>Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccc(C#N)cc3)C(C)(C)C2=O)cn1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080280876A1,COC(=O)CCN1Cc2ccc(-c3nc(-c4ccc(OC(C)C)c(Cl)c4)no3)cc2C1>>CC(C)Oc1ccc(-c2noc(-c3ccc4c(c3)CN(CCC(=O)O)C4)n2)cc1Cl,,CCO,,Cl,[Na+].[OH-],test
US20030105161A1,Cn1ccnc1[C@H](O)CCCNC(=O)OC(C)(C)C.N#Cc1cc(F)c(Cl)cc1F>>Cn1ccnc1[C@@H](CCCNC(=O)OC(C)(C)C)Oc1cc(Cl)c(F)cc1C#N,,CN(C)C=O,,O,[H-].[Na+],test
US20070105919A1,C1COCCN1.O=C(Nc1nc(-c2ccco2)c(N2CCOCC2)s1)c1ccc(Cl)nc1>>O=C(Nc1nc(-c2ccco2)c(N2CCOCC2)s1)c1ccc(N2CCOCC2)nc1,,C1COCCO1,,,,test
US05102914,CS(=O)(=O)Nc1ccc(C(=O)CBr)cc1.c1ccc(CNCC2CCc3ccccc3C2)cc1>>CS(=O)(=O)Nc1ccc(C(=O)CN(Cc2ccccc2)CC2CCc3ccccc3C2)cc1,,CC(C)=O,,CCN(C(C)C)C(C)C,,test
US04051248,NC(=O)C1(Nc2ccccc2)CCN(CC2CCc3ccccc3C2=O)CC1>>NC(=O)C1(Nc2ccccc2)CCN(CC2CCc3ccccc3C2O)CC1,,CO,O,Cl,[BH4-].[Na+],test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(C(=O)C2C(=O)OC(C)(C)OC2=O)CC1.Nc1n[nH]c2cccc(-c3cccnc3)c12>>CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4c(-c5cccnc5)cccc4nn23)CC1,,CC#N,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20050107381A1,CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1ccc(C=CC(C)=O)cn1>>CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1ccc(CCC(C)=O)cn1,O=[Pt]=O,CCOC(C)=O,,,,test
US20040067998A1,COC(=O)c1cccc([N+](=O)[O-])c1C.COC(OC)N(C)C>>COC(=O)c1cccc([N+](=O)[O-])c1C=CN(C)C,,CN(C)C=O,,O,,test
US20110198988A1,NNC(=O)c1ccc(F)cc1.O=C(Cl)c1ccc(F)cc1>>O=C(NNC(=O)c1ccc(F)cc1)c1ccc(F)cc1,,O,,CN1CCCC1=O,,test
US20160009744A1,Clc1cccc(C2(c3csc(C4OCCO4)c3)CCCN2)c1>>O=Cc1cc(C2(c3cccc(Cl)c3)CCCN2)cs1,,CC(C)=O,O,Cl,O=C([O-])O.[Na+],test
US20060100234A1,CCOC(=O)c1cc(O)c2nc(C)c(C)n2c1.c1ccc2c(c1)CC1OC21>>Cc1nc2c(O[C@@H]3c4ccccc4C[C@H]3O)cc(C(=O)O)cn2c1C,,CO,O,CCN(CC)CC,CCOC(C)=O,test
US20090324581A1,CC(C)(C)OC(=O)CCN(CC(=O)N1CCc2cc(OCc3ccc(C4CCC4)c(C(F)(F)F)c3)ccc21)C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C(O)CCNCC(=O)N1CCc2cc(OCc3ccc(C4CCC4)c(C(F)(F)F)c3)ccc21,,ClCCl,,,,test
US20130065902A1,CCOC(=O)Cn1c2c(c3cc(F)ccc31)C[C@@H](NC(=O)OCc1ccccc1)CC2>>CCOC(=O)Cn1c2c(c3cc(F)ccc31)CC(NC(=O)OCc1ccccc1)CC2,[Pd],CCO,,CC(=O)O,,test
US20020132842A1,Cc1cccc(Cl)c1N.Cl.Clc1nc2ccccc2[nH]1>>Cc1cccc(Cl)c1Nc1nc2ccccc2[nH]1.Cl,,CCO,,,,test
US20110207716A1,CC[C@@H]1C(=O)N(C)c2cnc(-c3ccnc(O)c3)nc2N1C1CCCC1.COP(=O)(OC)OC>>CC[C@@H]1C(=O)N(C)c2cnc(-c3ccn(C)c(=O)c3)nc2N1C1CCCC1,,C1COCCO1,,C1CCC2=NCCCN2CC1,,test
US20090069297A1,CO.COc1cnc2c(Sc3ccc(Nc4nnc(Cl)c5ccccc45)cc3)ccnc2c1>>COc1cnc2c(Sc3ccc(Nc4nnc(OC)c5ccccc45)cc3)ccnc2c1,,CO,,C[O-].[Na+],,test
US05840726,Cl.O=C1[C@H](Cc2c[nH]c3ccccc23)NCCN1CCc1ccccc1>>Cl.O=C1[C@H](Cc2c[nH]c3ccccc23)NCCN1CCc1ccccc1,,ClCCl,,,,test
US05393732,CC(C)C(C(C)C)C1NC1c1ncn(C(c2ccccc2)(c2ccccc2)c2ccccc2)n1.O=[PH](O)O.[N-]=[N+]=[N-]>>CC(C)OP(=O)(CC(N)C(N=[N+]=[N-])c1ncn(C(c2ccccc2)(c2ccccc2)c2ccccc2)n1)OC(C)C,,CO,O,[Cl-].[NH4+],,test
US04945091,ClC=C(Cl)CCl.O=c1[nH]ncc(Cl)c1Cl>>O=c1c(Cl)c(Cl)cnn1CC(Cl)=CCl,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20090306041A1,COC(=O)c1ccc(C2CC2)cc1C>>Cc1cc(C2CC2)ccc1C(=O)O,,CO,,[Na+].[OH-],,test
US20020082426A1,CC(C)(C)OC(=O)N1CC(O)C(SCc2ccccc2)C1.Cl>>Cl.OC1CNCC1SCc1ccccc1,,CCOC(C)=O,,,,test
US20050209291A1,Nc1nc2cc(NC(=S)NC(=O)c3ccccc3)ccc2s1>>NC(=S)Nc1ccc2sc(N)nc2c1,,CO,,C[O-].[Na+],,test
US20010034371A1,CCOC(=O)C(Cc1ccc(OCCc2ccc(OS(C)(=O)=O)cc2)cc1)OCC>>CCOC(Cc1ccc(OCCc2ccc(OS(C)(=O)=O)cc2)cc1)C(=O)O,,C1CCOC1,O,[Li+].[OH-],,test
US20130196998A1,CC(C)(C)OC(=O)CCN1CCC2(CC1)COc1ccc(O)cc12.OCc1ccccc1C(F)(F)F>>CC(C)(C)OC(=O)CCN1CCC2(CC1)COc1ccc(OCc3ccccc3C(F)(F)F)cc12,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160016948A1,C[Si](C)(C)CCOCCl.Cn1c(-c2cn[nH]c2)nc2cnc(Cl)cc21>>Cn1c(-c2cnn(COCC[Si](C)(C)C)c2)nc2cnc(Cl)cc21,,C1CCOC1,,CN(C)C=O,[H-].[Na+],test
US20080021069A1,COc1ccc(-n2c(SCc3ccc(Cl)cc3)nc3cc(Br)ccc32)cc1.Cl>>COc1ccc(-n2c(SCc3ccc(Cl)cc3)nc3cc(Br)ccc32)cc1.Cl,,CCOCC,,CCOC(C)=O,,test
US20100197683A1,COC1CCCCC1=O.Cc1nnc(N)[nH]1>>COC1CCCCC1Nc1nnc(C)[nH]1,,CC(=O)O,,O,[BH3-]C#N.[Na+],test
US20080153812A1,COC(=O)c1cnc(N2CCCN(C(C)C)CC2)nc1.COc1cc(CCc2cc(N)[nH]n2)cc(OC)c1>>COc1cc(CCc2cc(NC(=O)c3cnc(N4CCCN(C(C)C)CC4)nc3)[nH]n2)cc(OC)c1,,Cc1ccccc1,,C[Al](C)C,,test
US20150183791A1,CC(C)C[C@@H](Cn1ccc(-c2ccc3nccn3n2)cc1=O)N1C(=O)c2ccccc2C1=O.O=C1CCC(=O)N1Cl>>CC(C)C[C@H](N)Cn1ccc(-c2ccc3ncc(Cl)n3n2)cc1=O,,CCOC(C)=O,CN(C)C=O,,,test
US04316900,CCOC(=O)Cl.CN1CCN2c3ccccc3Cn3cccc3C2C1>>CCOC(=O)N1CCN2c3ccccc3Cn3cccc3C2C1,,CCOCC,c1ccccc1,,,test
US20100249119A1,C1COCCN1.CN(c1cccc(NC(=O)c2cccc(C(C)(C)C#N)c2)c1)c1ncc2nc(NC(=O)CCl)sc2n1>>CN(c1cccc(NC(=O)c2cccc(C(C)(C)C#N)c2)c1)c1ncc2nc(NC(=O)CN3CCOCC3)sc2n1,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US04764514,COc1ccc(S(=O)(=O)Cl)cc1.O=C1CSCN1>>COc1ccc(S(=O)(=O)N2CSCC2=O)cc1,,C1CCOC1,,[H-].[Na+],,test
US05143919,Nc1cnc2sc3c(c2c1-c1ccccc1Cl)CCC3.O=C(Cl)c1ccc(F)cc1F>>O=C(Nc1cnc2sc3c(c2c1-c1ccccc1Cl)CCC3)c1ccc(F)cc1F,,ClCCl,,CN(C)c1ccccc1,,test
US20020025965A1,Nc1ccc2c(c1)CC(c1cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn1)CC2>>Nc1ccc2c(c1)CC(c1c[nH]cn1)CC2,,CC(C)=O,CCOCC,CO,Cl,test
US20090221555A1,COc1cccc(C(C)(C)C#N)c1.O.[OH-]>>COc1cccc(C(C)(C)C(=O)O)c1,,O,,CO,,test
US20090163512A1,C=C(N=Cc1cc(F)ccc1C)O[Si](C)(C)C.CCCC(CCC)(Oc1ccc(Cl)cc1/C=C1\C(=O)N(C(=O)OC(C)(C)C)c2cc(Cl)ccc21)C(=O)OCC>>CCCC(CCC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)OCC,,Cc1ccccc1,,,,test
US20070249649A1,CC1(C)CC=C(c2cc(C(C)(C)NCCO)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1.Cl>>CC1(C)CC=C(c2cc(C(C)(C)NCCO)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1.Cl,,CCOCC,,,,test
US20040266774A1,Cc1[nH]c2c(C(=O)O)cccc2c1C.Cc1ncn(-c2cccc(N)c2)c1C>>Cc1ncn(-c2cccc(NC(=O)c3cccc4c(C)c(C)[nH]c34)c2)c1C,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20100010007A1,Cc1ccc(S(=O)(=O)OCC[C@H](O)c2ccccc2)cc1.Cc1nnc(C(C)C)n1C1CCNCC1>>Cc1nnc(C(C)C)n1C1CCN(CC[C@H](O)c2ccccc2)CC1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20150031689A1,CC(C)(C)OC(=O)N1CCC(N)CC1.Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(Cl)ncnc32)cc1>>CC(C)(C)OC(=O)N1CCC(Nc2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1,,CCO,,CCN(CC)CC,,test
US20120245136A1,CCI.COc1cc(C(=O)N2CCC3(CC2)CC(CO)c2ccccc2O3)ccc1OC(C)C>>CCOCC1CC2(CCN(C(=O)c3ccc(OC(C)C)c(OC)c3)CC2)Oc2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US06239074B1,Cn1c(C(F)(F)F)cc(=O)n(-c2ccc(Cl)c(C=C(Br)C(=O)O)c2)c1=O.O=S(Cl)Cl>>Cn1c(C(F)(F)F)cc(=O)n(-c2ccc(Cl)c(C=C(Br)C(=O)Cl)c2)c1=O,,Cc1ccccc1,,CN(C)C=O,,test
US20100317659A1,CCOC(=O)c1nc(O)c2cccc(C)c2n1.O=P(Cl)(Cl)Cl>>CCOC(=O)c1nc(Cl)c2cccc(C)c2n1,CN(C)C=O,,,,,test
US04788283,CC(=O)OC1CC(C)(C)NC(C)(C)C1.CCNCC.O=C(Cl)Cl>>CCN(CC)C(=O)N1C(C)(C)CC(OC(C)=O)CC1(C)C,,CCOC(C)=O,,,,test
US04282158,C(=C1CCCCO1)[P+](c1ccccc1)(c1ccccc1)c1ccccc1.O=CC1CCCCC1.[Cl-]>>O=C(C=CC1CCCCC1)CCCCCl,,Cc1ccccc1C,,,,test
US20040014634A1,CC(C)Cn1c(=O)n(C)c(=O)c2c(Sc3cccs3)c(C=O)sc21.CO>>CC(C)Cn1c(=O)n(C)c(=O)c2c(Cc3cccs3)c(CO)sc21,,CO,O,[BH4-].[Na+],,test
US04897490,CCOC(=O)C(=C(c1ccc(F)cc1)c1ccc(F)cc1)c1nnn(C(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>OCC(=C(c1ccc(F)cc1)c1ccc(F)cc1)c1nnn(C(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,ClCCl,,CC(C)C[Al+]CC(C)C.[H-],,test
US04122202,CNC.COc1ccc2c(c1OC)C(=O)OC2>>COc1ccc(CO)c(C(=O)N(C)C)c1OC,,CCO,,,,test
US04510139,C1CCNCC1.COc1ccc(-n2c(=O)oc(=O)c3ccccc32)cc1>>COc1ccc(Nc2ccccc2C(=O)N2CCCCC2)cc1,,CN(C)C=O,,,,test
US20130237535A1,Nc1cnc2cc(Br)ccc2c1.O=C(Cl)C1CC1>>O=C(Nc1cnc2cc(Br)ccc2c1)C1CC1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,,test
US20150225422A1,COC(=O)Cl.Nc1cc(-c2cnc3[nH]ncc3c2)ccn1>>COC(=O)Nc1cc(-c2cnc3[nH]ncc3c2)ccn1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090227622A1,CC1(C)OB(c2ccc(N)c(Cl)c2)OC1(C)C.Ic1cnc2cc(-c3ccncc3)ccn12>>Nc1ccc(-c2cnc3cc(-c4ccncc4)ccn23)cc1Cl,,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20130018049A1,N#CCC#N.NC1CC1.OC12CCCCC1OC1(O)CCCCC1O2>>N#Cc1c2c(n(C3CC3)c1N)CCCC2,,Cc1ccccc1,,,,test
US20080132503A1,COc1ccc(-c2ccc(/C=C/C(=O)Nc3cc(-c4cccs4)ccc3NC(=O)OC(C)(C)C)cn2)cc1OC>>COc1ccc(-c2ccc(/C=C/C(=O)Nc3cc(-c4cccs4)ccc3N)cn2)cc1OC,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070208048A1,CC(=O)Oc1cc(CBr)ccc1C(=O)OC(C)(C)C.CCCCn1c(-c2ccccc2)nc(-c2ccc(OC)cc2)c1CNCC1CCCCC1>>CCCCn1c(-c2ccccc2)nc(-c2ccc(OC)cc2)c1CN(Cc1ccc(C(=O)OC(C)(C)C)c(OC(C)=O)c1)CC1CCCCC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05026856,COC(=O)c1ccc2c(c1)CNC2.O=C(O)c1cn(-c2ccc(F)cc2)c2c(F)c(F)c(F)cc2c1=O>>COC(=O)c1ccc2c(c1)CN(c1c(F)cc3c(=O)c(C(=O)O)cn(-c4ccc(F)cc4)c3c1F)C2,,CN(C)C=O,,C1CCC2=NCCCN2CC1,Cl,test
US20100113502A1,C=CCN1c2ccc(NC(=O)OCC[Si](C)(C)C)cc2C2CN(C(=O)OC(C)(C)C)CCC21.Cl>>C=CCN1c2ccc(NC(=O)OCC[Si](C)(C)C)cc2C2CNCCC21.Cl,,C1COCCO1,,,,test
US05438052,CC(C)(ON)C(=O)NNC(=O)c1ccc(O)c(O)c1.Nc1nc(C(=O)C(=O)N[C@@H]2C(=O)N3C(C(=O)O)=C(CSc4nnc(-c5ccc(O)c(O)c5)o4)CS[C@H]23)cs1>>CC(C)(O/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(CSc3nnc(-c4ccc(O)c(O)c4)o3)CS[C@H]12)c1csc(N)n1)C(=O)NNC(=O)c1ccc(O)c(O)c1,,CC(=O)N(C)C,,Cl,,test
US20080085884A1,COC(=O)C1CCN(c2ccc(-n3ccc(OCc4ccccc4)cc3=O)cn2)C1>>O=C(O)C1CCN(c2ccc(-n3ccc(OCc4ccccc4)cc3=O)cn2)C1,,C1CCOC1,CO,[Na+].[OH-],,test
US20050065140A1,COc1ccc(Br)c(CC2CCN(CC3CO3)CC2)c1.[N-]=[N+]=[N-]>>COc1ccc(Br)c(CC2CCN(CC(O)CN=[N+]=[N-])CC2)c1,C1COCCOCCOCCOCCOCCO1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20100190766A1,COC(=O)C(NC(=O)c1ccc(C#CC#CC2CC2)cc1)C1(O)CC1.NO>>O=C(NC(C(=O)NO)C1(O)CC1)c1ccc(C#CC#CC2CC2)cc1,,CC(C)O,,,,test
US20110034437A1,BrC1=NOCC1.COC(=O)c1cncc(O)c1>>c1cncc(OC2=NOCC2)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20090239847A1,OC(c1cccnc1)c1nccnc1Cl>>O=C(c1cccnc1)c1nccnc1Cl,O=[Mn]=O,Cc1ccccc1,,,,test
US20090170916A1,CCOC(=O)c1cc(CCC(C)C)[nH]n1>>CC(C)CCc1cc(C(=O)O)n[nH]1,,CO,,[Na+].[OH-],,test
US20110065702A1,CC(C)N=C=O.Nc1cccc2c1NC(=O)C2>>CC(C)NC(=O)Nc1cccc2c1NC(=O)C2,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20070123493A1,COc1ccc(C#N)cc1C(=O)Nc1ccc(Cl)cc1.OO>>COc1ccc(C(N)=O)cc1C(=O)Nc1ccc(Cl)cc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090286778A1,COC(=O)c1cc2cc(c1)OCCSc1cccc(c1)Nc1nc(ncc1Cl)N2>>O=C(O)c1cc2cc(c1)OCCSc1cccc(c1)Nc1nc(ncc1Cl)N2,,C1CCOC1,CO,[Na+].[OH-],,test
US06300363B1,CC(=O)Cl.NC(=O)c1cccc(C(=O)c2[nH]c3cc(Cl)ccc3c2N)c1>>CC(=O)Nc1c(C(=O)c2cccc(C(N)=O)c2)[nH]c2cc(Cl)ccc12,,CCCCCC,CCOC(C)=O,,,test
US20120215027A1,CS(=O)(=O)CS(=O)(=O)Oc1ccccc1.CS(=O)(=O)Cl>>CS(=O)(=O)C(S(C)(=O)=O)S(=O)(=O)Oc1ccccc1,,O,,[Na+].[OH-],,test
US20140194469A1,CCOC(=O)/C=C/N(C)C.N#Cc1ccnc(NN)c1>>CCOC(=O)/C=C/NNc1cc(C#N)ccn1,,CCO,,CC(=O)O,,test
US20080146606A1,Cc1cc2c(-c3ccc(N(C)C(=O)OC(C)(C)C)cc3)ccnc2n1S(=O)(=O)c1ccccc1>>CNc1ccc(-c2ccnc3c2cc(C)n3S(=O)(=O)c2ccccc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05340808,CCOC(=O)c1ccc(NC(C)=O)cc1N.COC(=O)c1ccc(Cl)nn1>>COC(=O)c1ccc2nc3cc(NC(C)=O)ccc3c(=O)n2n1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04022769,C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CCC2=O>>C[C@]12CC[C@H]3[C@@H](CC=C4CC(=O)C=C[C@@]43C)[C@@H]1CCC2=O,,CS(C)=O,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US04122260,CCOC(=O)C(C(=O)NC1C(=O)N2C(C(=O)OC(C)(C)C)=C(COC(C)=O)CSC12)n1cccc1C=O>>CC(=O)OCC1=C(C(=O)O)N2C(=O)C(NC(=O)C(C(=O)O)n3cccc3C=O)C2SC1,,O=C(O)C(F)(F)F,,,,test
US20080287457A1,CC(C)(C)OC(=O)N1CCC(n2cnc(-c3ccccn3)c2)CC1.O=C(O)C(F)(F)F.O=Cc1ccc(-c2nc3cc[nH]c(=O)c3cc2-c2ccccc2)cc1>>O=C(O)C(F)(F)F.O=c1[nH]ccc2nc(-c3ccc(CN4CCC(n5cnc(-c6ccccn6)c5)CC4)cc3)ccc12,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20160264548A1,C/C=C/C(=O)Cl.NC(=O)c1cc(N2CCC(N)CC2)cnc1Oc1ccc(Oc2cccc(F)c2)cc1>>C/C=C/C(=O)NC1CCN(c2cnc(Oc3ccc(Oc4cccc(F)c4)cc3)c(C(N)=O)c2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04260755,FC(F)(F)c1cccc(-c2ccc(Cl)nn2)c1.NNC(=O)CO>>OCc1nnc2ccc(-c3cccc(C(F)(F)F)c3)nn12,,CCCCO,,,,test
US20040235822A1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4cccnc4)c(C(F)(F)F)c2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4cccnc4)c(C(F)(F)F)c2)CCN3CC(C)C)cc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US05550117,CCCN.CCN1c2ncccc2N=C(Cl)c2cccnc21>>CCCNC1=Nc2cccnc2N(CC)c2ncccc21,,Cc1ccccc1,,,,test
US20050245432A1,C1CCC(NC2CCCCC2)CC1.O=C1OCN(C(=O)OCc2ccccc2)[C@H]1CSCc1ccccc1>>C1CCC(NC2CCCCC2)CC1.CN[C@@H](CSCc1ccccc1)C(=O)O,,ClC(Cl)Cl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20100292210A1,CC(C)(C)[Si](C)(C)OCCNCC(O)c1ccccc1.O=C(Cl)c1ccc(Cl)nc1Cl>>CC(C)(C)[Si](C)(C)OCCN(CC(O)c1ccccc1)C(=O)c1ccc(Cl)nc1Cl,,C1CCOC1,CCOC(C)=O,,,test
US04788206,COc1ccc(/C(=C\C=C\C(=O)Oc2ccc([N+](=O)[O-])cc2)c2cccnc2)cc1.NCCCCc1cccnc1>>COc1ccc(/C(=C\C=C\C(=O)NCCCCc2cccnc2)c2cccnc2)cc1,,C1CCOC1,,,,test
US20130274227A1,N#Cc1c(Nc2cccnc2)n[nH]c1N.OO>>NC(=O)c1c(Nc2cccnc2)n[nH]c1N,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100216746A1,CSc1ncc(Cl)c(C(=O)O)n1.N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CN)c2F)c1>>CSc1ncc(Cl)c(C(=O)NCc2ccc(Cl)c(Oc3cc(Cl)cc(C#N)c3)c2F)n1,,CN(C)C=O,CO,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120122848A1,COc1cc2c(cc1N)C[C@@H]1[C@@H]3CCCC[C@]23CCN1C(=O)OCc1ccccc1.ClCCOCCCl>>COc1cc2c(cc1N1CCOCC1)C[C@@H]1[C@@H]3CCCC[C@]23CCN1C(=O)OCc1ccccc1,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US05952354,C1CCC2(C1)CCNCC2.O=C(NCCCCCCOC(=O)Oc1ccc([N+](=O)[O-])cc1)OC1CCN(C(=O)Oc2ccc(Oc3ccccc3)cc2)CC1>>O=C(NCCCCCCOC(=O)N1CCC2(CCCC2)CC1)OC1CCN(C(=O)Oc2ccc(Oc3ccccc3)cc2)CC1,,CN(C)C=O,ClCCl,CCN(CC)CC,Cl,test
US20040127538A1,CC(C)(C)OC(=O)n1nc(-c2cccc(F)c2)c2cc(N)ccc21.CS(=O)(=O)Cl>>CS(=O)(=O)Nc1ccc2[nH]nc(-c3cccc(F)c3)c2c1,,C1CCOC1,O,CCN(CC)CC,,test
US20110053955A1,CCOC(=O)c1[nH]c2ccc(OCc3ccccc3)cc2c1CCCNC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCCc1c(C(=O)O)[nH]c2ccc(OCc3ccccc3)cc12,,CCO,O,Cl,[Li+].[OH-],test
US20100190808A1,CCn1c(=O)c2cnc3c(OC)cccc3c2n(Cc2ccc(OC)cc2)c1=O>>CCn1c(=O)[nH]c2c(cnc3c(OC)cccc32)c1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090299072A1,BrCCCCBr.CCOC(=O)Cc1ccc([N+](=O)[O-])c(OCC2CC2)c1>>CCOC(=O)C1(c2ccc([N+](=O)[O-])c(OCC3CC3)c2)CCCC1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20050209241A1,CC(=O)c1ccc(N2CCN(C(=O)c3cc(S(C)(=O)=O)ccc3OC(C)C)CC2)c(F)c1.[Li]C>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2ccc(C(C)(C)O)cc2F)CC1,,C1CCOC1,CCOCC,,,test
US20040132716A1,CCOC(=O)C(CC(=O)N1CCC(N2Cc3ccccc3NC2=O)CC1)(Cc1ccc(C)c(C)c1)C(=O)OCC>>Cc1ccc(CC(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)C(=O)O)cc1C,,CCO,O,[K+].[OH-],,test
US20080108648A1,CN(C)C(OC(C)(C)C)OC(C)(C)C.O=C(O)c1ccc2cncn2c1>>CC(C)(C)OC(=O)c1ccc2cncn2c1,,CN(C)C=O,Cc1ccccc1,,,test
US20150126490A1,CC(O)Cc1cnc(N)c(Br)n1.O=C(NCc1ccccc1)c1ccc(B(O)O)cc1F>>CC(O)Cc1cnc(N)c(-c2ccc(C(=O)NCc3ccccc3)c(F)c2)n1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20090131444A1,COc1ccc2nccc(NC(=O)[C@@H]3CC[C@H](NCc4ccc5c(c4)OCCO5)CN3C(=O)OC(C)(C)C)c2n1>>COc1ccc2nccc(NC(=O)[C@@H]3CC[C@H](NCc4ccc5c(c4)OCCO5)CN3)c2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04508658,N#CC(=Cc1ccccc1)C(=O)O.Oc1c(F)c(F)c(F)c(F)c1F>>N#CC(=Cc1ccccc1)C(=O)Oc1c(F)c(F)c(F)c(F)c1F,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20160244431A1,CC(C)(C)OC(=O)NCCc1ccc(NC(=O)CN(Cc2ccccn2)Cc2ccccn2)cc1>>NCCc1ccc(NC(=O)CN(Cc2ccccn2)Cc2ccccn2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100094000A1,O=C(O)CCCC(F)(F)F>>OCCCCC(F)(F)F,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100266504A1,CCC(C)[Mg]Br.Clc1ccc2c(n1)CCN(Cc1ccccc1)C2>>CCC(C)c1ccc2c(n1)CCNC2.Cl,,C1CCOC1,,,,test
US20020156081A1,Nc1ncnc2[nH]nc(-c3ccc(Oc4ccccc4)cc3)c12.OC1CCC2(CC1)OCCO2>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CCC2(CC1)OCCO2,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100280071A1,CCO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C4CC4)ccc3[N+](=O)[O-])CC2)CC1>>CCO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C4CC4)ccc3N)CC2)CC1,[Ni],CCO,,NN,O,test
US05849911,CC(C)(C)OC(=O)NN(Cc1ccc(-c2cnccn2)cc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)C(F)(F)F>>CC(C)(C)OC(=O)NN(Cc1ccc(-c2cnccn2)cc1)C[C@H](O)[C@@H](N)Cc1ccccc1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20100305070A1,BrBr.COc1cc(C=O)cc(OC)c1>>COc1cc(C=O)c(Br)c(OC)c1,,CC(=O)O,,,,test
US20150291625A1,COc1cc(Oc2nccc3occc23)ccc1-c1nccnc1C>>Cc1nccnc1-c1ccc(Oc2nccc3occc23)cc1O,,ClCCl,,BrB(Br)Br,,test
US20050014941A1,N#CCNC(=O)[C@@H]1CCCC[C@H]1CS(=O)(=O)c1ccc(F)cc1.OCCCS>>N#CCNC(=O)[C@@H]1CCCC[C@H]1CS(=O)(=O)c1ccc(SCCCO)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110237584A1,COCOc1ccc(C=O)cc1.C[Si](C)(C)C(F)(F)F>>COCOc1ccc(C(O)C(F)(F)F)cc1,,C1CCOC1,CCOC(C)=O,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20060142348A1,C1COCCO1.CCOC(C)=O.CN(C)CC(=O)O.Oc1ccc2ccccc2c1>>Cn1ccc2c(Oc3ccc4ccccc4c3)cccc21,[Cu]I,C1COCCO1,CCOC(C)=O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US08980875B2,BrCc1ccccc1.Cn1cnc(-c2ccccc2)c1-c1ccccc1>>C[n+]1cn(Cc2ccccc2)c(-c2ccccc2)c1-c1ccccc1.[Br-],,Cc1ccccc1,,,,test
US20130244958A1,CC(Cl)OC(=O)Cl.O=P(OCCOCCOCCOCCO)(OCc1ccccc1)OCc1ccccc1>>CC(Cl)OC(=O)OCCOCCOCCOCCOP(=O)(OCc1ccccc1)OCc1ccccc1,,ClCCl,,c1ccncc1,,test
US20070219198A1,FC(F)(F)c1cccnc1N1CCNCC1.O=C(O)CC1CCCC1>>O=C(CC1CCCC1)N1CCN(c2ncccc2C(F)(F)F)CC1,,CN(C)C=O,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US20150274720A1,CCCC[Sn](CCCC)(CCCC)c1cccnc1.N#Cc1ccnc2c1cc(I)n2S(=O)(=O)c1ccccc1>>N#Cc1ccnc2c1cc(-c1cccnc1)n2S(=O)(=O)c1ccccc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,,,test
US20110257179A1,COc1ccc(Cn2cc(-c3csc(Nc4nccc(C)n4)n3)c(Br)n2)cc1.OB(O)c1ccccc1>>COc1ccc(Cn2cc(-c3csc(Nc4nccc(C)n4)n3)c(-c3ccccc3)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])O.[Na+],,test
US20090298815A1,CI.COC(=O)c1cccc([N+](=O)[O-])c1O>>COC(=O)c1cccc([N+](=O)[O-])c1OC,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130029987A1,CCOC(=O)c1cnc(SC)nc1NC(C)(C)C>>CSc1ncc(C(=O)O)c(NC(C)(C)C)n1,,CCO,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[Na+].[OH-],test
US20080269210A1,C1COCCN1.Clc1nc(Cl)c2scc(I)c2n1>>Clc1nc(N2CCOCC2)c2scc(I)c2n1,,CO,,,,test
US04110333,O=c1[nH]c2ccccc2n1CCCN1CCC(Nc2ccc(Cl)cc2[N+](=O)[O-])CC1>>Nc1cc(Cl)ccc1NC1CCN(CCCn2c(=O)[nH]c3ccccc32)CC1,[Ni],CO,,[H][H],,test
US20090076002A1,FCCCBr.OC1C[C@@H]2CC[C@H](C1)N2>>OC1CC2CCC(C1)N2CCCF,,CN(C)C=O,,CCN(CC)CC,,test
US20070105831A1,COc1cc(Br)cc(OC)c1>>COc1cc(O)cc(Br)c1,,ClCCl,,BrB(Br)Br,,test
US05247085,CCOP(=O)(COC(CON)COC(C)=O)OCC.O=CNc1c(Cl)ncnc1Cl>>CCOP(=O)(COC(CONc1ncnc(Cl)c1NC=O)COC(C)=O)OCC,,C1COCCO1,,CCN(CC)CC,,test
US20090247746A1,CCOC(=O)c1cc2cc(C)cc(N)c2[nH]1.O=S(=O)(Cl)c1cccs1>>CCOC(=O)c1cc2cc(C)cc(NS(=O)(=O)c3cccs3)c2[nH]1,,c1ccncc1,,,,test
US20100105667A1,CCOC(=O)c1ccc(-c2cc(OC)cc(OC)c2F)c2nccnc12.COc1cc(OC)c(Cl)c(-c2ccc(C(=O)Nc3ccc(CN4CCN(C)CC4)cn3)c3nccnc23)c1Cl>>COc1cc(OC)c(F)c(-c2ccc(C(=O)Nc3ccc(CN4CCN(C)CC4)cn3)c3nccnc23)c1,,CO,ClCCl,,,test
US20060160879A1,CCOC(=O)c1c(NC(=O)c2ccc(OC)cc2)c2ccc(-c3ccc(OC(C)C)cc3)cc2n1Cc1cccc(Cl)c1>>COc1ccc(C(=O)Nc2c(CO)n(Cc3cccc(Cl)c3)c3cc(-c4ccc(OC(C)C)cc4)ccc23)cc1,,C1CCOC1,O,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20060135578A1,COc1cc(C=O)ccc1O.Cc1nn(-c2ccccn2)cc1CO>>COc1cc(C=O)ccc1OCc1cn(-c2ccccn2)nc1C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20050043386A1,C=COC(=O)CCCCC.CC(CO)(CO)NC(=O)OC(C)(C)C>>CCCCCC(=O)OC[C@@](C)(CO)NC(=O)OC(C)(C)C,,CC(C)OC(C)C,,,,test
US04134983,COc1ccc(C(=O)C=O)cc1.N.O=Cc1cccnc1.c1cncc(-c2ncc[nH]2)c1>>COc1ccc(-c2c[nH]c(-c3cccnc3)n2)cc1,,CO,O,CC(=O)[O-].[Na+],,test
US05473041,C=CCCBr.O=[N+]([O-])c1ccc(-c2ccc([N+](=O)[O-])cc2O)cc1>>C=CCCOc1cc([N+](=O)[O-])ccc1-c1ccc([N+](=O)[O-])cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150105404A1,COC(=O)c1cc(Br)ccc1NC(=O)Cc1cccc(C(F)(F)F)c1>>O=c1[nH]c2ccc(Br)cc2c(O)c1-c1cccc(C(F)(F)F)c1,,C1CCOC1,O,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20150238558A1,COC[C@H](c1ccccc1)N(CC1(C(=O)N[C@H]2C[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N(C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(C)(C)C)C2)CC1)C(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(C)(C)C>>COC[C@H](c1ccccc1)N(CC1(C(=O)N[C@H]2C[C@@H](C(=O)N[C@@H]3CCCc4ccccc43)N(C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(C)(C)C)C2)CC1)C(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)C(C)(C)C,,ClCCl,,C1CCNCC1,,test
US20100291437A1,CS(=O)(=O)Cl.Oc1ccc(F)cc1F>>CS(=O)(=O)Oc1ccc(F)cc1F,,O,,CCN(CC)CC,Cc1ccccc1,test
US20150167017A1,Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1.O=C(OC(=O)c1ccccc1)c1ccccc1>>O=C(Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1)c1ccccc1,,CN(C)C=O,c1ccncc1,O,,test
US20130252940A1,CCN(C(C)C)C(C)C.CCOC(C)=O.CN(C)C=O.COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.Nc1ccc(F)cc1.O=C(O)C1(C(=O)O)CN(Cc2ccccc2)C1>>COc1cc2nccc(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CN(Cc5ccccc5)C4)cc3)c2cc1OC.O=C(O)C1(C(=O)O)CN(Cc2ccccc2)C1,,CCOC(C)=O,CN(C)C=O,,,test
US20120157427A1,Cc1c([N+](=O)[O-])cnn1-c1ccc(S(C)(=O)=O)cc1.Cc1nn(-c2ccc(S(C)(=O)=O)cc2)cc1[N+](=O)[O-]>>Cc1c([N+](=O)[O-])cnn1-c1ccc(S(C)(=O)=O)cc1.Cc1nn(-c2ccc(S(C)(=O)=O)cc2)cc1[N+](=O)[O-],[Pd],CCO,,,,test
US04883815,O=C1CCC2=C(CCc3cc(Cl)c(Cl)cc32)N1>>Clc1cc2c(cc1Cl)C1=C(CC2)NCCC1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US05294625,Cl.Cl.O=C(c1ccc(N2CCCC2)cc1)C1CCNCC1>>Cl.Cl.c1cc(N2CCCC2)ccc1CN1CCCCC1,[Pd],O,,CCO,,test
US20100016350A1,CN(C)[C@H]1CCNC1.Fc1ccc(Br)cn1>>CN(C)[C@H]1CCN(c2ccc(Br)cn2)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US06972288B1,CCOC(=O)C=CC(=O)Cl.Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCC1CC1>>CCOC(=O)C=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCC1CC1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20160120850A1,BrCc1cccc(Br)c1.COC(=O)C(C)C>>COC(=O)C(C)(C)Cc1cccc(Br)c1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20130079341A1,CCOC(=O)c1sc2ncc(-c3ccco3)nc2c1N>>Nc1c(C(=O)O)sc2ncc(-c3ccco3)nc12,,CCO,O,[K+].[OH-],,test
US04453010,O=C(Oc1ccccc1)c1ccc(O)cc1>>O=C(c1ccc(O)cc1)c1ccc(O)cc1,,O,,CS(=O)(=O)O,,test
US20150246934A1,CN(C(=O)OC(C)(C)C)c1cc(F)cc2c1[nH]c1nc(S(=O)(=O)Cc3ccccc3)nc(S(=O)(=O)Cc3ccccc3)c12.CS.Cc1ncc(O)cn1>>CNc1cc(F)cc2c1[nH]c1nc(Oc3cnc(C)nc3)nc(SCc3ccc(OC)cc3)c12,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20100094000A1,Cc1n[nH]c(-c2ccc(F)cc2)c1Br.OCC1CCOC1>>Cc1nn(CC2CCCO2)c(-c2ccc(F)cc2)c1Br,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080153850A1,COC(=O)c1cccnc1Cl.O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(B(O)O)ccc1Cl>>COC(=O)c1cccnc1-c1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,O,O=C([O-])[O-].[K+].[K+],test
US20050277671A1,CC(C)n1c(=O)[nH]c2ccccc21.NCC1CCN(CC2(C(=O)O)CCC2)CC1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)n1c(=O)n(C(=O)NCC2CCN(CC3(C(=O)O)CCC3)CC2)c2ccccc21,,ClCCl,,CCN(CC)CC,Cc1ccc(S(=O)(=O)O)cc1,test
US20150291595A1,CNS(=O)(=O)c1ccc(OC)cc1>>CNS(=O)(=O)c1ccc(O)cc1,,CCOC(C)=O,ClCCl,BrB(Br)Br,,test
US04501860,CCOC(=O)NN.O=C(Cl)Oc1ccccc1>>CCOC(=O)NNC(=O)Oc1ccccc1,,ClCCl,,c1ccncc1,,test
US05403823,COC(Cl)Cl.Cc1cc2c(cc1C)C(C)(C)C(C)C2C(C)C>>Cc1cc2c(c(C)c1C=O)C(C)(C)C(C)C2C(C)C,Cl[Ti](Cl)(Cl)Cl,,,ClCCl,,test
US20060252931A1,C1CN(C2CCOCC2)CCN1.Cc1cc(C[C@@H](OC(=O)N2CCC(n3c(=O)[nH]c4c5ccccc5ncc43)CC2)C(=O)O)cc(C)c1O>>Cc1cc(C[C@@H](OC(=O)N2CCC(n3c(=O)[nH]c4c5ccccc5ncc43)CC2)C(=O)N2CCN(C3CCOCC3)CC2)cc(C)c1O,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20020016328A1,CCC(COS(C)(=O)=O)Nc1cc(C)nc(Oc2c(C)cc(Cl)cc2C)c1C(=O)OC.CCN>>CCNCC(CC)Nc1cc(C)nc(Oc2c(C)cc(Cl)cc2C)c1C(=O)OC,,CC#N,,CCN(CC)CC,[I-].[Na+],test
US20110217311A1,CC(=O)C1CCC(F)(F)CC1.O=C(OO)c1cccc(Cl)c1>>OC1CCC(F)(F)CC1,,ClC(Cl)Cl,,,,test
US04018773,COc1ccc(OC)c2c1CC1OC1C2.COc1ccccc1N1CCNCC1>>COc1ccccc1N1CCN([C@@H]2Cc3c(OC)ccc(OC)c3C[C@H]2O)CC1,,Cc1ccccc1C,,CC(C)O,,test
US20100168080A1,COc1cc(OCCCN2CCC(O)(Cc3ccc(Cl)cc3)C(C)(C)C2)c(N)cc1Cl.N#CO[K]>>COc1cc(OCCCN2CCC(O)(Cc3ccc(Cl)cc3)C(C)(C)C2)c(NC(N)=O)cc1Cl,,CN(C)C=O,O,CC(=O)O,,test
US06150359,CCn1c(=O)ccc2cnc(F)cc21.Nc1ccc(N2CCCCC2)cc1>>CCn1c(=O)ccc2cnc(Nc3ccc(N4CCCCC4)cc3)cc21,CC(=O)O,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US05380834,CC(=O)Cl.O=C1C=C[C@H]2CO[C@@H]1O2.[Li]C>>CC(=O)O[C@@]1(C)C=C[C@H]2CO[C@@H]1O2,,C1CCOC1,,,,test
US04939159,Fc1ccc(-c2c[nH]c3ccncc23)cc1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(c1ccccc1)n1cc(-c2ccc(F)cc2)c2cnccc21,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US06002008,CNC.COc1cc2c(Nc3cc(O)c(Cl)cc3F)c(C#N)cnc2cc1OCCCl>>COc1cc2c(Nc3cc(O)c(Cl)cc3F)c(C#N)cnc2cc1OCCN(C)C,,C1CCOC1,,[I-].[Na+],,test
US20130261295A1,CCOCOCl.Cc1cccc(C=O)c1O>>CCOCOc1c(C)cccc1C=O,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20050288340A1,NC(=S)c1ccc(Cl)cc1.O=C(CCl)CCl.[C-]#N>>N#CCc1csc(-c2ccc(Cl)cc2)n1,,CCO,,O,,test
US20040181064A1,COC(=O)[C@@H]1[C@@H](O)CCN1C(=O)Nc1ccc(C#N)c(Cl)c1C>>Cc1c(NC(=O)N2CC[C@H](O)[C@H]2C(=O)O)ccc(C#N)c1Cl,,[Na+],[OH-],Cl,,test
US20030069294A1,COC(=O)C(C)(O)c1ccc(OCC(=O)OC(C)(C)C)cc1.Fc1ccc(CBr)cc1>>COC(=O)C(Cc1ccc(OCC(=O)OC(C)(C)C)cc1)OCc1ccc(F)cc1,O=[Ag],Cc1ccccc1,,,,test
US20070208040A1,CCC(=O)O.CCOC(=O)c1c(C)csc1N.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CCOC(=O)c1c(C)csc1NC(=O)NC,,Cc1ccccc1,,CCN(CC)CC,,test
US20030036655A1,COc1ccc(Cc2ccc(N)cc2)s1.ClC1=NCCN1>>COc1ccc(Cc2ccc(NC3=NCCN3)cc2)s1,,CC#N,ClCCl,O=S(=O)(O)O,,test
US04243609,C=CCCCCCCCCC=CCCCO.CS(=O)(=O)Cl>>C=CCCCCCCCCC=CCCCOS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20150239900A1,CC(C)(C)OC(=O)N1CCN(c2ccnc3cc(Cl)c(I)cc23)CC1.OB(O)c1ccccc1Cl>>CC(C)(C)OC(=O)N1CCN(c2ccnc3cc(Cl)c(-c4ccccc4Cl)cc23)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20100197683A1,CCCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(-c2ccc(OC(C)C)cc2)c2ncnn12.O=C([O-])O.[NH3+]O>>CCCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(-c2ccc(OC(C)C)cc2)c2ncnn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20120010228A1,CN(C)C(OC(C)(C)C)OC(C)(C)C.O=C(O)c1ccccc1N1CN(c2ccccc2)C2(CCN(C(=O)OCc3ccccc3)CC2)C1=O>>CC(C)(C)OC(=O)c1ccccc1N1CN(c2ccccc2)C2(CCN(C(=O)OCc3ccccc3)CC2)C1=O,,CCOC(C)=O,Cc1ccccc1,,,test
US06340694B1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.CS(=O)(=O)c1ccc(-c2oc3ccccc3c(=O)c2-c2ccc(F)cc2)cc1>>CS(=O)(=O)c1ccc(-c2oc3ccccc3c(=S)c2-c2ccc(F)cc2)cc1,,Cc1ccccc1,,,,test
US20110319394A1,C1CCOC1.CCOC(=O)Cn1c(Oc2ccc(-n3c(=O)n(CC)c4cccnc43)cc2)nc2ccccc21.[Mg]CBr>>CCn1c(=O)n(-c2ccc(Oc3nc4ccccc4n3CC(C)(C)O)cc2)c2ncccc21,,C1CCOC1,,[Ca+2].[Cl-].[Cl-],,test
US05387685,COc1cc2c(cc1OC)CNCC2.COc1ccc(C(C#N)(CCCCl)Sc2ccc(C)cc2)cc1OC>>COc1ccc(C(C#N)(CCCN2CCc3cc(OC)c(OC)cc3C2)Sc2ccc(C)cc2)cc1OC,,CN(C)C=O,,Cl,[I-].[K+],test
US04544759,CC(N)=S.COc1ccc(C#N)cc1>>COc1ccc(C(N)=S)cc1,,CN(C)C=O,,Cl,,test
US20150218133A1,COc1cc2cc(-c3c(I)ccnc3OC)[nH]c2cc1NC(=O)OC(C)(C)C>>COc1cc2cc(-c3c(I)ccnc3OC)[nH]c2cc1N,,ClCCl,,O=C(O)C(F)(F)F,,test
US05220026,COc1cccc(Br)c1C(=O)O.Cc1n[nH]c2cc([N+](=O)[O-])ccc12>>COc1cccc(-n2nc(C)c3ccc([N+](=O)[O-])cc32)c1C(=O)O,O=[Cu],O=[N+]([O-])c1ccccc1,,O,O=C([O-])[O-].[K+].[K+],test
US20060264460A1,N#Cc1cccc(C=O)c1.N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1>>N#Cc1cccc(CNc2ccc3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)c1,,CCO,,[BH3-]C#N.[Na+],,test
US04997855,CCCCCCCCC(Cl)CC(F)(Cl)C(F)(F)Cl>>CCCCCCCCC(Cl)CC(F)=C(F)F,[Zn],CC(C)O,,,,test
US05527908,Cl.Cn1nc(N)c2c(=O)n3c(nc21)SCC3>>Cn1nc(Cl)c2c(=O)n3c(nc21)SCC3,,O,,O=N[O-].[Na+],,test
US20040006065A1,CC(C)(C)OC(=O)[C@@H]1CCc2ncc(NC(=O)OCc3ccccc3)c(=O)n21.CI>>CC(C)(C)OC(=O)C1(C)CCc2ncc(NC(=O)OCc3ccccc3)c(=O)n21,,C1CCOC1,,,,test
US20130331378A1,CC(C)(C)OC(=O)C(C#N)c1ccc(C(F)(F)F)cn1>>N#CCc1ccc(C(F)(F)F)cn1,,CC#N,CCOC(C)=O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20060122263A1,COc1ccc(CN)cc1.c1ccc(C(c2ccccc2)[C@H]2C[C@@H]3O[C@@H]3CO2)cc1>>COc1ccc(CN[C@H]2CO[C@@H](C(c3ccccc3)c3ccccc3)C[C@@H]2O)cc1,,CCO,,,,test
US20010034051A1,CCN(C(C)C)C(C)C.NCCNc1ccc([N+](=O)[O-])cn1.O=[N+]([O-])c1ncc(Br)nc1-c1ccc(Cl)cc1Cl>>O=[N+]([O-])c1ccc(NCCNc2cnc([N+](=O)[O-])c(-c3ccc(Cl)cc3Cl)n2)cc1,,CN(C)C=O,,,,test
US05723450,COc1c(NOCc2ccccc2)ccnc1C.Cc1ccc(S(=O)(=O)OC2CCC3(CC2)OCC(C)(C)CO3)cc1>>COc1c(N(OCc2ccccc2)C2CCC3(CC2)OCC(C)(C)CO3)ccnc1C,,C1CCOC1,CS(C)=O,[H][H],[H-].[Na+],test
US20150284409A1,C=CCBr.Oc1cc2ccccc2c(Cl)n1>>C=CCOc1cc2ccccc2c(Cl)n1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20140315857A1,NCc1ccnc2ccccc12.O=S(=O)(Cl)c1ccc(Br)s1>>O=S(=O)(NCc1ccnc2ccccc12)c1ccc(Br)s1,,ClCCl,,CCN(CC)CC,Cl,test
US20150239835A1,BrCCCCCBr.[C-]#[N+]CSc1ccccc1OC>>[C-]#[N+]C1(Sc2ccccc2OC)CCCCC1,,CN(C)C=O,,[H-].[Na+],,test
US05436247,CCOC(=O)c1c(Cn2cncn2)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC(C)C)c1.Cl>>CCOC(=O)c1c(Cn2cncn2)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC(C)C)c1.Cl,,CCO,,ClCCl,,test
US20050197350A1,CCNC.Cc1cnc(Cl)nc1Cl>>CCN(C)c1nc(Cl)ncc1C,,C1CCOC1,,,,test
US20110190278A1,Cc1cc(F)ccc1C(=O)O.O=[N+]([O-])O>>Cc1cc(F)c([N+](=O)[O-])cc1C(=O)O,,O=S(=O)(O)O,,,,test
US20060252779A1,CC1NC(=S)Nc2ccc(Cl)cc21.CI>>CSC1=Nc2ccc(Cl)cc2C(C)N1.I,,CC(C)=O,CCOCC,,,test
US05495023,C/C=C(/C=C/CO)CC.O=C1NC(=O)c2ccccc21>>CC=C(C=CCN1C(=O)c2ccccc2C1=O)CC,,C1CCOC1,ClCCl,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080306082A1,CC(C)(C)OC(=O)NCc1ccc2cc(-c3ccnc(Cl)n3)sc2c1.CN1CCN(CCCN)CC1>>CN1CCN(CCCNc2nccc(-c3cc4ccc(CNC(=O)OC(C)(C)C)cc4s3)n2)CC1,,C1COCCO1,,,,test
US20140275179A1,CCOC(=O)CCc1cc(F)c(O)c(F)c1.CS(=O)(=O)OCc1c(Cl)nsc1-c1ccc(Cl)cc1>>CCOC(=O)CCc1cc(F)c(OCc2c(Cl)nsc2-c2ccc(Cl)cc2)c(F)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150266857A1,CC(C)(C)OC(=O)N1Cc2ccc(-c3cn(C(=O)OC(C)(C)C)c4cc(F)ccc34)cc2C1>>Fc1ccc2c(-c3ccc4c(c3)CNC4)c[nH]c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090227640A1,CCOC(=O)CCCCC(/C=C/c1ccccc1OCc1ccc(C(C)(C)C)cc1)CCc1ccc(C#N)cc1>>CC(C)(C)c1ccc(COc2ccccc2/C=C/C(CCCCC(=O)O)CCc2ccc(C#N)cc2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20090029994A1,COc1cc(O)c([N+](=O)[O-])cc1C(F)(F)F.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1cc(OS(=O)(=O)C(F)(F)F)c([N+](=O)[O-])cc1C(F)(F)F,,ClC(Cl)Cl,ClCCl,c1ccncc1,O=C([O-])O.[Na+],test
US20150368265A1,CNC(=O)c1c(-c2nnc(C)o2)oc2cc(N(C)S(C)(=O)=O)c(Br)cc12.C[Sn](C)(C)c1ccc2c(n1)-c1cc3c(F)cccc3n1CO2>>CNC(=O)c1c(-c2nnc(C)o2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3CO4)cc12,,CC(C)O,,[Cl-].[Li+],,test
US20130165436A1,Brc1cc2c(cn1)OCCN2.O=C(Cl)OCc1ccccc1>>O=C(OCc1ccccc1)N1CCOc2cnc(Br)cc21,,C1CCOC1,,[H-].[Na+],,test
US05321041,N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(=O)O.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O>>CCCCCCCCCCCC=CC=CC(O)=CC=CC(=O)O,,O=P([O-])([O-])[O-],,[Ca+2].[Cl-].[Cl-],,test
US20120214762A1,C#C[Si](C)(C)C.O=C1CCc2cccnc21>>C#CC1(O)CCc2cccnc21,,C1CCOC1,O,[Li]CCCC,,test
US04594342,CN(CCCl)C(=O)OCc1ccccc1.COc1ccc([C@@H]2Sc3cc(OCc4ccccc4)ccc3NC(=O)[C@@H]2O)cc1>>COc1ccc([C@@H]2Sc3cc(OCc4ccccc4)ccc3N(CCN(C)C(=O)OCc3ccccc3)C(=O)[C@@H]2O)cc1,,CS(C)=O,,[K+].[OH-],,test
US04820834,NC1N=C(c2ccccc2F)c2ccccc2NC1=O.O=C(Cl)C=Cc1ccccc1>>O=C(C=Cc1ccccc1)NC1N=C(c2ccccc2F)c2ccccc2NC1=O,,ClCCl,,CCN(CC)CC,,test
US20120190701A1,CS(=O)(=O)Cl.Cc1c(CO)cc(Br)cc1C(F)(F)F>>Cc1c(COS(C)(=O)=O)cc(Br)cc1C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20100249120A1,O=C1CCC(=O)N1Br.O=C1c2cnc3[nH]ncc3c2C(=O)N1CCc1ccccc1>>O=C1c2cnc3[nH]nc(Br)c3c2C(=O)N1CCc1ccccc1,,ClCCl,,O,,test
US20150361060A1,CCOC(=O)C=NO.NCCN1C2CC3CC(C2)CC1C3>>O=C(C=NO)NCCN1C2CC3CC(C2)CC1C3,,CCO,,,,test
US04056621,CN=C(NC#N)SC.Cc1[nH]cnc1CSCCS.Cl>>CN=C(NC#N)SCCSCc1nc[nH]c1C.Cl,,O,c1ccncc1,,,test
US20150057260A1,CC(C)I.Clc1cc2[nH]ncc2c(Cl)n1>>CC(C)n1ncc2c(Cl)nc(Cl)cc21,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100087427A1,CC(C)Oc1ccc(S(=O)(=O)Cl)cc1.COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2N)C(C)C)ccc1OC>>COCCCOc1cc(C(=O)N(C[C@@H]2CNC[C@H]2NS(=O)(=O)c2ccc(OC(C)C)cc2)C(C)C)ccc1OC,,O,,CC#N,CC#N,test
US20030149001A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.Cc1c(Br)c(=O)n(C2CCCC2)c2nc(Nc3ccc(N4CCN(C(=O)OC(C)(C)C)C(C)(C)C4)cn3)ncc12>>C=C(OCC)c1c(C)c2cnc(Nc3ccc(N4CCN(C(=O)OC(C)(C)C)C(C)(C)C4)cn3)nc2n(C2CCCC2)c1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US04323578,CN=C=O.CS/C(=N/O)C(F)(F)F>>CNC(=O)O/N=C(/SC)C(F)(F)F,CCN(CC)CC,,,,,test
US20160090508A1,CCCCCCCCCCCC(=O)O.CCCCCCCCCCCCCCCC(=O)Cl.O=C[C@H](O)[C@@H](O)[C@H](O)CO.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>CCCCCCCCCCCCCCCC(=O)O.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO,,ClCCl,,,,test
US20030109556A1,CC(C)(C)[Si](C)(C)Cl.N[C@@H](CCO)C(=O)O>>CC(C)(C)[Si](C)(C)OCCC(N)C(=O)O,,CN(C)C=O,,O,c1c[nH]cn1,test
US20090281092A1,COC(=O)C(F)(F)CNC1CCCC1.O=[N+]([O-])c1cnc(Cl)nc1Cl>>COC(=O)C(F)(F)CN(c1nc(Cl)ncc1[N+](=O)[O-])C1CCCC1,,CC(C)=O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20090155299A1,CCOC(C)(OCC)OCC.COc1ccc(O[C@@H]2O[C@@H](C)[C@H](OCc3ccccc3)[C@@H](O)[C@H]2O)cc1>>COc1ccc(O[C@@H]2O[C@@H](C)[C@H](OCc3ccccc3)[C@@H](O)[C@H]2OC(C)=O)cc1,,CN(C)C=O,,,,test
US20040110749A1,CCn1nc(Cl)c(CSC2=NOC(C)(C)C2)c1Cl.O=C(OO)c1cccc(Cl)c1>>CCn1nc(Cl)c(CS(=O)(=O)C2=NOC(C)(C)C2)c1Cl,,ClC(Cl)Cl,,O,,test
US20080318960A1,NNC(=O)C(NC(=O)c1ccccc1)c1n[nH]c(=O)c2ccccc12.O=Cc1ccccc1Br>>O=C(NC(C(=O)N/N=C/c1ccccc1Br)c1n[nH]c(=O)c2ccccc12)c1ccccc1,,CCO,,CC(=O)O,,test
US04672067,CN(CCc1c[nH]c2ccc(C#N)cc12)Cc1ccccc1>>CN(CCc1c[nH]c2ccc(CN)cc12)Cc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130281402A1,C1=COCCC1.O=C1c2ccccc2C(=O)N1O>>O=C1c2ccccc2C(=O)N1OC1CCCCO1,Cc1ccc(S(=O)(=O)O)cc1,C1COCCO1,ClCCl,,,test
US05223498,CN=C=S.Cc1ccc(N2CCOCC2)c(N)c1>>CNC(=S)Nc1cc(C)ccc1N1CCOCC1,,ClCCl,,,,test
US20120316161A1,CCCc1nc2c(-c3ccc(C)cc3)c(C(CCC)C(=O)OCC)c(C)nc2n1C>>CCCc1nc2c(-c3ccc(C)cc3)c(C(CCC)C(=O)O)c(C)nc2n1C,,CCO,CO,[Na+].[OH-],,test
US20060194816A1,CCOC(=O)c1c(C(=O)c2ccc(Cl)cc2Cl)oc2cc(OS(=O)(=O)C(F)(F)F)ccc12.Cc1cccc(B(O)O)c1>>CCOC(=O)c1c(C(=O)c2ccc(Cl)cc2Cl)oc2cc(-c3cccc(C)c3)ccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05308840,C=CC(=O)Nc1cc(C)ccc1O.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>Cc1ccc(O)c(NC(=O)CCN2CCN(C(c3ccccc3)c3ccccc3)CC2)c1,,CCO,,,,test
US20070082907A1,COc1ccc(C=O)c(C)c1>>COc1ccc(CO)c(C)c1,,CCO,,[BH4-].[Na+],,test
US20140371201A1,COc1cc(Br)c(F)cc1-n1c(=O)cnc2cc(S(=O)(=O)Cl)ccc21.Nc1cccnn1>>COc1cc(Br)c(F)cc1-n1c(=O)cnc2cc(S(=O)(=O)Nc3cccnn3)ccc21,,CCOC(C)=O,CO,ClCCl,c1ccncc1,test
US20090312323A1,CCO.Cc1ccc(Cl)cc1C(=O)O>>CCOC(=O)c1cc(Cl)ccc1C,,CCOCC,,O=S(Cl)Cl,,test
US20080269192A1,C#CCBr.C[C@H]1COCc2nc3c(N)nc4ccc(O)cc4c3n21>>C#CCOc1ccc2nc(N)c3nc4n(c3c2c1)[C@@H](C)COC4,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20150045378A1,CCOC(=O)CC(c1cc(Cl)ncn1)C1CC1.COc1ccc(F)c(-c2ncc(CO)cc2CC(C)(C)C)c1>>CCOC(=O)CC(c1cc(OCc2cnc(-c3cc(OC)ccc3F)c(CC(C)(C)C)c2)ncn1)C1CC1,,C1CCOC1,,Cl,[H-].[Na+],test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(=O)N(C)OC)CC2)c2ccnn12.C[Mg]Br>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(C)=O)CC2)c2ccnn12,,C1CCOC1,,CCOC(C)=O,,test
US03991071,CCCN(CCOc1ccccc1)C(=O)Cl.c1c[nH]cn1>>CCCN(CCOc1ccccc1)C(=O)n1ccnc1,,C1CCOC1,,,,test
US20110152239A1,CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O.CN(C)C=O.Oc1cccc2[nH]nnc12>>COc1ccccc1[C@H](C)N,,CN(C)C=O,,CC(C)N=C=NC(C)C,,test
US20040116475A1,CNC.COc1ccc(-n2nc(N)cc2-c2ccc(OCc3ccccc3)cc2)cc1.O=C(n1ccnc1)n1ccnc1>>COc1ccc(-n2nc(NC(=O)N(C)C)cc2-c2ccc(OCc3ccccc3)cc2)cc1,,C1CCOC1,CN1CCCC1=O,,,test
US04507498,CCCc1c(O)ccc(C(C)=O)c1O.CCCc1c(OCCCC(=O)OCC)ccc(C(C)=O)c1OCCCOCCCBr>>CCCc1c(OCCCOCCCOc2c(C(C)=O)ccc(OC(CC)C(=O)OCC)c2CCC)ccc(C(C)=O)c1O,,CN(C)C=O,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20100094000A1,CC1(C)OB(c2ccc3c(c2)NC(=O)CO3)OC1(C)C.Cc1nn(CC2CCSCC2)c(-c2ccc(F)cc2)c1Br>>Cc1nn(CC2CCSCC2)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070078135A1,CC(C)(C)OC(=O)N1CCC(O)CC1.Oc1cnc(Br)c(Cl)n1>>CC(C)(C)OC(=O)N1CCC(Oc2cnc(Br)c(Cl)n2)CC1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110071150A1,CCOC(=O)CC(=O)c1ccccn1.CNN>>Cn1nc(-c2ccccn2)cc1O,,CCO,,,,test
US20100305133A1,CCOC(=O)CNC(=O)c1c(O)c(-c2cnccn2)cc2nccnc12>>O=C(O)CNC(=O)c1c(O)c(-c2cnccn2)cc2nccnc12,,CCO,,[Na+].[OH-],,test
US20150259295A1,CC(O)c1cccc(C(F)(F)F)c1.Cn1ncc(-c2ccccc2F)c1N.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(OC(=O)Nc1c(-c2ccccc2F)cnn1C)c1cccc(C(F)(F)F)c1,,Cc1ccccc1,ClCCl,,,test
US20100222355A1,CC(C)(C)OC(=O)N(CCCl)CCCl.N#CCc1cccc(F)c1>>CC(C)(C)OC(=O)N1CCC(C#N)(c2cccc(F)c2)CC1,,CS(C)=O,ClCCl,[H-].[Na+],,test
US20090105275A1,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCNC2)c1.Cn1nnc2cc(CBr)ccc21>>CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCN(Cc3ccc4nnn(C)c4c3)C2)c1,,CC#N,CCOC(C)=O,CCN(C(C)C)C(C)C,CN(C)C=O,test
US04282242,COC(=O)c1cc[nH]c1.Cc1ccccc1C(=O)Cl>>COC(=O)c1c[nH]c(C(=O)c2ccccc2C)c1,,CCOCC,,ClCCl,O,test
US20100249123A1,N#CC1(c2ccc(N)cc2)CCCC1.O=C(Cl)c1ccc2c(c1)OCCO2>>N#CC1(c2ccc(NC(=O)c3ccc4c(c3)OCCO4)cc2)CCCC1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20120322841A1,Cc1ccc(S(=O)(=O)n2cc3c(n2)CCCC3(O)c2ccc(Cl)cc2)cc1>>Cc1ccc(S(=O)(=O)n2cc3c(n2)CCC=C3c2ccc(Cl)cc2)cc1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20150203486A1,Brc1cnc(I)nc1.O=C1CCC1>>OC1(c2ncc(Br)cn2)CCC1,,Cc1ccccc1,O,[Li]CCCC,,test
US20090105219A1,CCOC(=O)CCc1cn(CC(=O)OC(C)(C)C)c2cccc([N+](=O)[O-])c12>>CCOC(=O)CCc1cn(CC(=O)OC(C)(C)C)c2cccc(N)c12,[Pd],CCO,,,,test
US08999970B2,C[C@H]1CNCCc2ccc(Cl)cc21.O=C(O)c1cc(=O)[nH]c(=O)[nH]1>>C[C@H]1CNCCc2ccc(Cl)cc21.O=C(O)c1cc(=O)[nH]c(=O)[nH]1,,CC(C)O,CCOC(C)=O,CC(C)=O,,test
US20150087646A1,CC(C)(C)OC(=O)NNc1ccc(C(F)(F)F)cc1.O=C=NC(=O)c1cc(S(=O)(=O)NC2CC2)ccc1Cl>>O=c1[nH]c(-c2cc(S(=O)(=O)NC3CC3)ccc2Cl)nn1-c1ccc(C(F)(F)F)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04564386,CNC.Cc1ccc(S(=O)(=O)Cl)c(C)c1NS(=O)(=O)C(F)(F)F>>Cc1ccc(S(=O)(=O)N(C)C)c(C)c1NS(=O)(=O)C(F)(F)F,,C1CCOC1,,,,test
US20030171360A1,CCOC(=O)N1CCC(Nc2ccccc2N)CC1.S=C(Cl)Cl>>S=c1[nH]c2ccccc2n1C1CCNCC1,,ClCCl,,CCN(CC)CC,,test
US20130029938A1,CC(C)(C)OC(=O)NCCCC[C@H](N)C(=O)OC(C)(C)C.CCCC[C@]1(CC)CS(=O)(=O)c2cc(C=O)c(OC)cc2[C@@H](c2ccccc2)N1>>CCCC[C@]1(CC)CS(=O)(=O)c2cc(CN[C@@H](CCCCN)C(=O)O)c(OC)cc2[C@@H](c2ccccc2)N1,,ClCCl,,C1COCCO1,Cl,test
US20150080588A1,CC(C)(C)OC(=O)N[C@@H]1C=C[C@](CCO)(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1>>CC(C)(C)OC(=O)N[C@@H]1C=C[C@](CC=O)(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US04788195,CC(=O)c1ccc(Nc2nccc(-c3cccnc3)n2)cc1.NC=O>>CC(NC=O)c1ccc(Nc2nccc(-c3cccnc3)n2)cc1,,O,,O=CO,,test
US20040058918A1,CC(=O)OC(C)=O.O=C(O)Cc1ccc(Cl)c(Cl)c1.O=Cc1ccncc1>>O=C(O)C(=O)C(=Cc1ccncc1)c1ccc(Cl)c(Cl)c1,,CCOC(C)=O,O,c1ccncc1,,test
US20140288072A1,Cc1nn(C(C)(C)C)c2nc(N(CC3CC3)CC3CC3)c(CNCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)cc12.Clc1ncc(Br)cn1>>Cc1nn(C(C)(C)C)c2nc(N(CC3CC3)CC3CC3)c(CN(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)c3ncc(Br)cn3)cc12,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060094761A1,CC(=O)Oc1c(C)nc(C2CC2)c(CO)c1COC(=O)O>>CCCc1nc(C)c(OC(C)=O)c(C)c1CO,[Pd],CO,O,,,test
US20090105275A1,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCNC2)c1.O=S(=O)(Cl)c1ccccc1C(F)(F)F>>CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCN(S(=O)(=O)c3ccccc3C(F)(F)F)C2)c1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20090118314A1,CCOC(=O)C(CCCCl)C(=O)OCC.Oc1ccc2cc(-c3nc4ccccc4o3)ccc2c1>>CCOC(=O)C(CCCOc1ccc2cc(-c3nc4ccccc4o3)ccc2c1)C(=O)OCC,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US05288735,CBr.O=C(CNC(=O)OCc1ccccc1)Nc1nnc(SCc2ccccc2)s1>>Cn1nc(SCc2ccccc2)sc1=NC(=O)CNC(=O)OCc1ccccc1,,CO,O,C[O-].[Na+],,test
US20140080816A1,C=O.NCCN1CC2CCCCCN2c2ccccc21>>c1cc2c3c(c1)N1CCCCCC1CN3CCNC2,,CCO,,O=C(O)C(F)(F)F,,test
US20140235895A1,CCCCCCCCc1ccc(C(=O)CC[N+](=O)[O-])cc1>>CCCCCCCCc1ccc(C(O)CC[N+](=O)[O-])cc1,,CCOC(C)=O,O,CO,[BH4-].[Na+],test
US06248740B1,Clc1ccc2ncnn2n1.NCCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1>>c1ccc(C(OC2CCN(CCCCNc3ccc4ncnn4n3)CC2)c2ccccc2)cc1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20080070928A1,Nc1c([N+](=O)[O-])cc(Oc2cccnc2)c(Cl)c1Oc1cccnc1>>Nc1cc(Oc2cccnc2)c(Cl)c(Oc2cccnc2)c1N,[Fe],CO,O,[Cl-].[NH4+],,test
US20130261086A1,CC(COCc1ccccc1)COS(C)(=O)=O.CC1(C)OB(c2cn[nH]c2)OC1(C)C>>CC(COCc1ccccc1)Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080045528A1,CC(C)N=C=O.CNC(=O)c1cc(Oc2ccc3nc(N[C@H]4CCCNC4)sc3c2)ccn1>>CNC(=O)c1cc(Oc2ccc3nc(N[C@H]4CCCN(C(=O)NC(C)C)C4)sc3c2)ccn1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US04929634,N#Cc1cc[nH]c1-c1ccc(Cl)cc1.O=S(=O)(Cl)Cl>>N#Cc1cc(Cl)[nH]c1-c1ccc(Cl)cc1,,CC(=O)O,,,,test
US04615726,CCOC(=O)c1ccccc1C1=NC(=O)C(C)(C(C)C)N1.COC(=O)Cl>>CCOC(=O)c1ccccc1C1=NC(=O)C(C)(C(C)C)N1C(=O)OC,,c1ccncc1,,,,test
US06303593B1,BrCc1ccccc1.c1ccc(-c2ccncc2)nc1>>C1=C(c2ccccn2)CCN(Cc2ccccc2)C1,,CC#N,CN(C)C=O,[BH4-].[Na+],,test
US20060116383A1,CCOC(=O)CC(c1ccc(-c2ccccc2)cc1)n1cnc2ccccc21>>O=C(O)CC(c1ccc(-c2ccccc2)cc1)n1cnc2ccccc21,,Cl,,CC#N,,test
US20150274733A1,COC(=O)CNC(C)(C)CC(=O)OC.O=C(Cl)OCc1ccccc1>>COC(=O)CN(C(=O)OCc1ccccc1)C(C)(C)CC(=O)OC,,C1CCOC1,,O=C([O-])O.[Na+],,test
US04282242,O=C(CBr)c1ccc(-c2ccccc2)cc1.c1ccn2cncc2c1>>O=C(C[n+]1cc2ccccn2c1)c1ccc(-c2ccccc2)cc1.[Br-],,C1CCOC1,,CCOCC,,test
US20060189606A1,BrC1CCC1.CCOc1ccc2c(C#N)c[nH]c2c1>>CCOc1ccc2c(C#N)cn(C3CCC3)c2c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20010031874A1,COc1ccc(C(=O)Nc2ccccc2)cc1N.Cn1cnc(S(=O)(=O)Cl)c1>>COc1ccc(C(=O)Nc2ccccc2)cc1NS(=O)(=O)c1cn(C)cn1,,c1ccncc1,,,,test
US20160264578A1,CCOC(=O)c1c(N)nn(-c2ccc([N+](=O)[O-])cc2)c1C.COc1ccc(N)nn1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCOC(=O)c1c(NC(=O)Nc2ccc(OC)nn2)nn(-c2ccc([N+](=O)[O-])cc2)c1C,,ClCCl,O,CCN(CC)CC,,test
US20070032494A1,CN(C)C(=S)Cl.O=[N+]([O-])c1cc(Cl)c(O)c(Cl)c1>>CN(C)C(=S)Oc1c(Cl)cc([N+](=O)[O-])cc1Cl,,CCOC(C)=O,CN(C)C=O,C1CN2CCN1CC2,,test
US20140113931A1,CC(C)C[C@@H](Nc1cnc(C#N)c(Nc2cc(-c3ccccc3)no2)c1)C(N)=O.OO>>CC(C)C[C@@H](Nc1cnc(C(N)=O)c(Nc2cc(-c3ccccc3)no2)c1)C(N)=O,,CCO,CS(C)=O,CC(=O)O,[Na+].[OH-],test
US20160264567A1,O=C1c2ccccc2C(=O)N1Cc1cc(N2CCC(OC(F)(F)F)C(F)(F)C2)ncc1F>>NCc1cc(N2CCC(OC(F)(F)F)C(F)(F)C2)ncc1F,,CO,,NN,O,test
US05840952,CO[Si](CCCCl)(OC)OC.S>>CO[Si](CCCS)(OC)OC,,CO,,,,test
US20150246922A1,CCOC(OCC)c1cc2cc(C#N)cc(Br)c2n1C(=O)OC(C)(C)C>>N#Cc1cc(Br)c2[nH]c(C=O)cc2c1,,C1CCOC1,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20090325981A1,CNC(=O)COc1ccccc1C=O.NNC(=S)c1ccc(Cl)cc1.O=C(Cl)c1c(F)cc(F)cc1F>>CNC(=O)COc1ccccc1C1SC(c2ccc(Cl)cc2)=NN1C(=O)c1c(F)cc(F)cc1F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150299198A1,COC(=O)c1ccc([N+](=O)[O-])cc1CBr.Cc1c([C@@H](O)CN2CCC(N)CC2)ccc2c1COC2=O>>Cc1c([C@@H](O)CN2CCC(N3Cc4cc([N+](=O)[O-])ccc4C3=O)CC2)ccc2c1COC2=O,,CO,,CCN(CC)CC,Cl,test
US20060111340A1,N#CCC(N)=S.O=C1c2ccc(Cl)cc2Sc2ccccc2C1Br>>N#CCc1nc2c(s1)-c1ccccc1Sc1cc(Cl)ccc1-2,,CCO,,,,test
US20120028931A1,CC(C)(C)OC(=O)N1CCC(=CC(=O)ON=C(N)c2cccc(Cl)c2)CC1>>CC(C)(C)OC(=O)N1CCC(=Cc2nc(-c3cccc(Cl)c3)no2)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20030055012A1,CCC(=O)OC(=O)CC.CCNS(=O)(=O)c1ccc(-c2c(-c3ccccc3)noc2C)cc1>>CCC(=O)N(CC)S(=O)(=O)c1ccc(-c2c(-c3ccccc3)noc2C)cc1,,O=S(=O)(O)O,,,,test
US20030100567A1,CC(C)(C)[SiH2]OC(C)(C)c1cc(Cl)nc(Nc2ncc(C#N)s2)c1>>N#Cc1cnc(Nc2cc(CO)cc(Cl)n2)s1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20030207926A1,COC(=O)Cc1ccc(O)c(NC(=O)C(F)(F)C(F)(F)C(F)(F)F)c1>>COC(=O)Cc1ccc2oc(C(F)(F)C(F)(F)C(F)(F)F)nc2c1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05589477,COc1ccc(-c2nc(C)cc(Cl)n2)cc1.OCCN1CCN(C(c2ccccc2)c2ccccc2)CC1>>COc1ccc(-c2nc(C)cc(OCCN3CCN(C(c4ccccc4)c4ccccc4)CC3)n2)cc1,,C1CCOC1,,[H-].[Na+],,test
US05393730,BrP(Br)Br.OC1OCOc2ccc1c(F)c2F>>Fc1c2ccc(c1F)C(Br)OCO2,,CCOCC,,CO,O,test
US04169896,CCCCCCCCCCNC(C)=O>>CCCCCCCCCCNCC,,CCOCC,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20060106014A1,BrBr.Cc1c(O)ccc(O)c1C>>Cc1c(O)cc(Br)c(O)c1C,,CCOCC,,,,test
US07732446B1,COc1cc2c(CC(=O)N(C)Cc3ccccc3)cnc(CNC(=O)OC(C)(C)C)c2cc1OC.Cl>>COc1cc2c(CC(=O)N(C)Cc3ccccc3)cnc(CN)c2cc1OC.Cl,,CCOC(C)=O,,,,test
US05294623,CCOC(=O)C=CC1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1>>CCOC(=O)CCC1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1,[Pd],CCO,,[H][H],,test
US05140011,CC(C)[C@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cncn1C(=O)OC(C)(C)C)NC(=O)[C@@H](CC(=O)C(C)(C)C)Cc1ccccc1)C(=O)c1ccccc1>>CC(C)[C@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](CC(=O)C(C)(C)C)Cc1ccccc1)C(=O)c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US07094798B1,COc1ccc2c(c1)c1c3c(c(-c4ccccc4Cl)cc1n2CCCO[Si](C)(C)C(C)(C)C)C(=O)NC3=O>>COc1ccc2c(c1)c1c3c(c(-c4ccccc4Cl)cc1n2CCCO)C(=O)NC3=O,,C1CCOC1,CO,Cl,,test
US20100173933A1,Clc1ccc(-c2csc(COCc3ccccc3)n2)cc1>>OCc1nc(-c2ccc(Cl)cc2)cs1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20150361284A1,CC(C)(c1ccccc1)c1ccccc1O.OCCCl>>CC(C)(c1ccccc1)c1ccc(OCCO)cc1,,ClCCl,,O,[Na+].[OH-],test
US20140274930A1,BrCc1ccccc1.CC1(C)OC[C@H]([C@H]2OC(=O)[C@@]3(CO)OC(C)(C)O[C@@H]23)O1>>CC1(C)OC[C@H]([C@H]2OC(=O)[C@@]3(COCc4ccccc4)OC(C)(C)O[C@@H]23)O1,,CN(C)C=O,,[H-].[Na+],,test
US20140235660A1,COc1ccc(-c2sc3cc(OC)ccc3c2Oc2ccc(/C=C/C(=O)OC(C)(C)C)cc2)cc1>>O=C(O)/C=C/c1ccc(Oc2c(-c3ccc(O)cc3)sc3cc(O)ccc23)cc1,,CO,ClCCl,BrB(Br)Br,,test
US20050014759A1,CNNC.N#Cc1cc(C(=O)c2ccc(F)cc2)n2c1ccc1ccccc12>>CN(C)c1ccc(C(=O)c2cc(C#N)c3ccc4ccccc4n23)cc1,,O,,CN(C)C=O,,test
US20090099207A1,CC(C)(C)OC(=O)N(Cc1cccc(C(C)(C)C)c1)[C@H]1CS(=O)(=O)C[C@@H](Cc2ccc(Br)cc2)[C@H]1O>>CC(C)(C)OC(=O)N(Cc1cccc(C(C)(C)C)c1)[C@H]1CS(=O)(=O)C[C@@H](Cc2ccc(Br)cc2)C1=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US20140128637A1,COc1cc(C)c(-c2cccc3cccc(-c4cc(C=O)c(OC)cc4C)c23)cc1C=O>>Cc1cc(O)c(C=O)cc1-c1cccc2cccc(-c3cc(C=O)c(O)cc3C)c12,,ClCCl,,BrB(Br)Br,,test
US04801706,O=C(c1ccccc1)n1ccn(-c2ccccc2)ccn1C(=O)c1ccccc1>>O=C(c1ccccc1)N1CCNCCN1C(=O)c1ccccc1,[Pd],C1COCCO1,,,,test
US20050239861A1,CCOC(=O)[C@@H]1CC(O)CN1C(C)=O.CS(=O)(=O)Cl>>CCOC(=O)[C@@H]1CC(OS(C)(=O)=O)CN1C(C)=O,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20070232583A1,Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2nc(-c3cccc(S(=O)(=O)NC(C)(C)C)c3)cs2)n1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2nc(-c3cccc(S(N)(=O)=O)c3)cs2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05506242,COC(=O)[C@@H](C1CCC(=O)CC1)N(Cc1ccccc1)S(=O)(=O)c1ccc(OC)cc1.[NH4+]>>COC(=O)[C@@H](C1CCC(N)CC1)N(Cc1ccccc1)S(=O)(=O)c1ccc(OC)cc1,,CC(C)O,ClCCl,[BH3-]C#N.[Na+],,test
US20150175557A1,CC1(C)CC(=O)CCC1O.NO>>CC1(C)C/C(=N/O)CCC1O,,CO,,Cl,O=C([O-])O.[Na+],test
US20070213331A1,C1CCOC1.CCCN(C)C(=O)c1cc(C(=O)O)cc(C(=O)OCC)c1.CCN=C=NCCCN(C)C>>CCCN(C)C(=O)c1cc(C(=O)OCC)cc(-c2nc(C)no2)c1,,ClCCl,,Cl,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05808132,O=C(O)C(c1ccccc1)(C(F)(F)F)C(F)(F)F>>O=C(O)C(c1ccccc1)C(F)(F)F,,CO,,O,[Na+].[OH-],test
US20080051418A1,CCCOc1cc(CCC(=O)OCC)[nH]n1.Fc1ccc(CBr)c(F)c1>>CCCOc1cc(CCC(=O)OCC)n(Cc2ccc(F)cc2F)n1,,CN(C)C=O,,O,[H-].[Na+],test
US20090306041A1,C1CNC1.O=C1CCc2cc(F)ccc21>>O=C1CCc2cc(N3CCC3)ccc21,,CS(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US07034039B2,CC(=O)c1ccc2c(=O)n(CC(C)C)c(CNC(=O)OC(C)(C)C)c(-c3ccccc3)c2c1.Cl>>CC(=O)c1ccc2c(=O)n(CC(C)C)c(CN)c(-c3ccccc3)c2c1.Cl,,CCOC(C)=O,,,,test
US20140135332A1,COc1ccc(-c2coc([C@H](C)O)n2)cc1.O=C(O)c1ccc([N+](=O)[O-])cc1>>COc1ccc(-c2coc([C@@H](C)OC(=O)c3ccc([N+](=O)[O-])cc3)n2)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100041891A1,CCOC(=O)c1cc2cccc(OC)c2s1>>COc1cccc2cc(C(=O)O)sc12,,C1CCOC1,CO,[Na+].[OH-],,test
US20120114765A1,N=C(N)n1nnc2ccccc21.Nc1ccc(NC(=O)c2cc([N+](=O)[O-])c(Sc3c(Cl)cncc3Cl)s2)cc1>>N=C(N)Nc1ccc(NC(=O)c2cc([N+](=O)[O-])c(Sc3c(Cl)cncc3Cl)s2)cc1,,CC#N,,CCN(CC)CC,Cl,test
US20150025070A1,O=C(O)CN1CCC(C(=O)c2ccccn2)CC1.O=c1[nH]c(CNCC2CC2)nc2c1COCC2>>O=C(c1ccccn1)C1CCN(CC(=O)N(Cc2nc3c(c(=O)[nH]2)COCC3)CC2CC2)CC1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20010039285A1,COc1ccc2c(c1)CCNC2c1cccs1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccc2c(c1)CCN(C(=O)C(F)(F)F)C2c1cccs1,,ClCCl,,CCN(CC)CC,,test
US20150119362A1,Clc1cccc(-c2cc(N=C(c3ccccc3)c3ccccc3)c3c(n2)CCC3)c1>>Nc1cc(-c2cccc(Cl)c2)nc2c1CCC2,,C1CCOC1,,Cl,,test
US04702561,NC1CCCCC1.O=C1c2ccccc2C(=O)c2c1cccc2[N+](=O)[O-]>>O=C1c2ccccc2C(=O)c2c(NC3CCCCC3)cccc21,,Clc1ccccc1Cl,,,,test
US04563310,COP(OC)c1ccccc1.O=[N+]([O-])c1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1[N+](=O)[O-]>>COP(=O)(c1ccccc1)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-],,CC#N,,,,test
US20020133021A1,COC(=O)N1CCc2cc(N3C[C@H](CNC(C)=O)OC3=O)ccc2C1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COC(=O)N1CCc2cc(N3C[C@H](CNC(C)=S)OC3=O)ccc2C1,,C1CCOC1,,,,test
US20090054405A1,Brc1csc(Br)n1.Fc1ccc(S)cc1>>Fc1ccc(Sc2nc(Br)cs2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04340595,BrCC1CO1.O=C1CCCc2c(O)cccc2N1>>O=C1CCCc2c(cccc2OCC2CO2)N1,,CC(=O)CC(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20100063106A1,COC(=O)c1nn(CCc2ccccc2)cc1NC(=O)CSc1ccc(Br)cc1>>O=C(CSc1ccc(Br)cc1)NC1CN(CCc2ccccc2)N=C1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090149488A1,COc1cc2c(cc1OCc1ccccc1)C1Cc3c(Cl)cc(OC)c(OCCO)c3CN1CC2>>COc1cc2c(cc1O)C1Cc3c(Cl)cc(OC)c(OCCO)c3CN1CC2,[Ni],,,,,test
US20110172224A1,Cl.Clc1ncnc2sc3c(c12)CCC1(C3)OCCO1.Nc1ccc(OCc2ccccn2)c(Cl)c1>>Cl.Clc1cc(Nc2ncnc3sc4c(c23)CCC2(C4)OCCO2)ccc1OCc1ccccn1,,CCO,,,,test
US06294527B1,CC(=O)c1occc1Br.CI.S=C=S>>CSc1cc(=O)c2occc2s1,,CN(C)C=O,O,CO,[H-].[Na+],test
US20090209532A1,COC(=O)c1cc(OC)c(OC)cc1CBr.Nc1ccc(Cl)cc1>>COc1cc2c(cc1OC)C(=O)N(c1ccc(Cl)cc1)C2,,Cc1ccccc1,,CCN(CC)CC,,test
US04324796,CCOC(=O)C1(CCCc2cccc(C(F)(F)F)c2)CO1.[Na+]>>O=C([O-])C1(CCCc2cccc(C(F)(F)F)c2)CO1.[Na+],,C1CCOC1,,O,,test
US20090156642A1,CCOC(=O)c1cc(Sc2ccc(Cl)nc2)n(-c2cc(F)ccc2Cl)n1.CN>>CNC(=O)c1cc(Sc2ccc(Cl)nc2)n(-c2cc(F)ccc2Cl)n1,,CO,,,,test
US20040058903A1,O=Cc1ccccc1F.Oc1cccc(C(F)(F)F)c1>>O=Cc1ccccc1Oc1cccc(C(F)(F)F)c1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20160184305A1,BrBr.COc1ccc2[nH]c(=O)oc2c1>>COc1cc2oc(=O)[nH]c2cc1Br,,O,,CC(=O)O,,test
US05654322,CCCC(=O)Cl.CCc1nnc(N)s1>>CCCC(=O)Nc1nnc(CC)s1,,CCN(CC)CC,CCOC(C)=O,Cc1ccccc1,O=C([O-])O.[Na+],test
US20050153970A1,C=O.O=C(N[C@@H]1CCCC[C@H]1CNC1CCc2cc(F)ccc2C1)OCc1ccccc1>>CN(C[C@@H]1CCCC[C@H]1NC(=O)OCc1ccccc1)C1CCc2cc(F)ccc2C1,CC(=O)O,CC#N,,[Na+].[OH-],,test
US20150322002A1,CC(C)(C)OC(=O)c1cc(Cl)c(CO[Si](C)(C)C(C)(C)C)cc1F>>CC(C)(C)OC(=O)c1cc(Cl)c(CO)cc1F,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080004300A1,CC(C)c1ccc(N)cc1.O=[N+]([O-])O>>CC(C)c1ccc(N)cc1[N+](=O)[O-],,O=S(=O)(O)O,,,,test
US05192525,CCN(CC)CCOc1ccc(/C(=C(/CCO)c2ccccc2)c2ccccc2)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>CCN(CC)CCOc1ccc(/C(=C(/CCOS(=O)(=O)c2ccc(C)cc2)c2ccccc2)c2ccccc2)cc1,,ClCCl,,c1ccncc1,,test
US20140336383A1,NCCC1CC1.O=C=NC1CCCCC1>>O=C(NCCC1CC1)NC1CCCCC1,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20020165221A1,COC(=O)[C@@H]1C[C@@H](N=[N+]=[N-])CN1C(=O)OC(C)(C)C.Cl>>COC(=O)[C@@H]1C[C@@H]([NH3+])CN1C(=O)OC(C)(C)C.[Cl-],[Pd],CCO,,,,test
US05155108,CCC(CC)(CO)CS(N)(=O)=O.Clc1ccc2nccn2n1>>CCC(CC)(COc1ccc2nccn2n1)CS(N)(=O)=O,,CN(C)C=O,,Cl,[H-].[Na+],test
US20080171765A1,Cc1cc(Cl)c2cc3c(cc2n1)OCO3.O=[N+]([O-])c1ccc(O)cc1>>Cc1cc(Oc2ccc([N+](=O)[O-])cc2)c2cc3c(cc2n1)OCO3,,ClC(Cl)Cl,,,,test
US20160185785A1,CC(C)(C)OC(=O)N1CC=C(c2ccc(-n3ncc4c(=O)n(CC5(O)CCN(C(=O)C6CC6)CC5)cnc43)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccc(-n3ncc4c(=O)n(CC5(O)CCN(C(=O)C6CC6)CC5)cnc43)cc2)CC1,[Pd],CN(C)C=O,,[H][H],,test
US20090221555A1,CNC(=O)CCNC(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CNC(=O)CCN.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20070238726A1,COc1ccc(Cn2ncc3c(N(CCN4CCOCC4)c4ccc([N+](=O)[O-])cc4F)ccnc32)cc1>>COc1ccc(Cn2ncc3c(N(CCN4CCOCC4)c4ccc(N)cc4F)ccnc32)cc1,,CCO,,,,test
US06333431B1,C[Mg]Br.O=C(O)c1c(F)cc(F)c(F)c1F>>Cc1c(F)c(F)cc(F)c1C(=O)O,,CCOCC,,Cl,O,test
US20140349998A1,CCOC(=O)c1c[nH]c2ncnc(Cl)c12.C[Si](C)(C)CCOCCl>>CCOC(=O)c1cn(COCC[Si](C)(C)C)c2ncnc(Cl)c12,,CN(C)C=O,,[H-].[Na+],,test
US20080132503A1,CCOC(=O)/C=C/CP(=O)(OCC)OCC.O=C1CCN(Cc2ccc3c(c2)OCO3)C1>>CCOC(=O)/C=C/C=C1\CCN(Cc2ccc3c(c2)OCO3)C1,,COCCOC,,[H-].[Na+],,test
US20090275606A1,CCCC[Sn](CCCC)(CCCC)COCOC.O=Cc1c(Nc2ccc(Br)cc2F)c(F)c(=O)n2c1CCC2>>COCOCC(O)c1c(Nc2ccc(Br)cc2F)c(F)c(=O)n2c1CCC2,,C1CCOC1,,[Li]CCCC,,test
US20150191452A1,COc1ccc(C2=CCNCC2)cc1.Cl>>COc1ccc(C2CCNCC2)cc1.Cl,[Pd],CO,,[H][H],,test
US06951906B1,CC(C)(C)c1cccc(C(C)(C)C)c1O.[Li]CCCC>>[Li]Oc1c(C(C)(C)C)cccc1C(C)(C)C,,Cc1ccccc1,,,,test
US20030232789A1,CC(=O)Oc1ccccc1C(=O)Cl.N#Cc1ccc(N)cc1>>CC(=O)Oc1ccccc1C(=O)Nc1ccc(C#N)cc1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20030134896A1,C=C[C@@H](OCc1ccc(OC)cc1)[C@@H](OC)[C@@H](C(=O)NCOC)C1=CCCCC1.C=C[Mg]Br>>C=CC(=O)[C@@H](C1=CCCCC1)[C@H](OC)[C@@H](C=C)OCc1ccc(OC)cc1,,C1CCOC1,,O,[Cl-].[NH4+],test
US20150025068A1,Nc1ccc(C(=O)O)c(O)c1.O=S(=O)(Cl)c1ccc(Br)s1>>O=C(O)c1ccc(NS(=O)(=O)c2ccc(Br)s2)cc1O,,C1COCCO1,,CCOC(C)=O,,test
US20110098290A1,COCOc1cc(O)c(C(C)C)cc1C(=O)OC>>COCOc1cc(O)c(C(C)C)cc1C(=O)O,,CO,O,[K+].[OH-],,test
US20040176431A1,CC(=O)Nc1cc(F)c(C(=O)c2sc(Nc3ccc(S(N)(=O)=O)cc3)nc2N)c(F)c1>>Nc1cc(F)c(C(=O)c2sc(Nc3ccc(S(N)(=O)=O)cc3)nc2N)c(F)c1,,CCO,,Cl,,test
US20120283239A1,CN.Cn1nnc2c(C#N)nc(-c3ccc(OCCC4CCNCC4)c(C(F)(F)F)c3)cc21.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CNC(=O)N1CCC(CCOc2ccc(-c3cc4c(nnn4C)c(C#N)n3)cc2C(F)(F)F)CC1,,ClCCl,,,,test
US20110112063A1,CCc1cc(N)n[nH]1.Clc1ncc(Cl)c(Cl)n1>>CCc1cc(Nc2nc(Cl)ncc2Cl)n[nH]1,,CC(C)O,,O,O=C([O-])[O-].[Na+].[Na+],test
US20090093454A1,COc1ccc([C@@H](C)N2CCC[C@@H]3CCc4cccnc4[C@@H]32)cc1>>c1cnc2c(c1)CC[C@H]1CCCN[C@@H]21,,ClCCl,,O=C(O)C(F)(F)F,,test
US04971982,CC(C)(Oc1ccc(C#N)cc1)C(=O)Cc1cnccn1>>CC(C)(Oc1ccc(C#N)cc1)C(O)Cc1cnccn1,,CCO,O,[BH4-].[Na+],,test
US04639442,[N-]=[N+]=NCCCOC12C=CC=CC1CC2C(=O)N1CCCCC1>>NCCCOC12C=CC=CC1CC2CN1CCCCC1,,C1CCOC1,CCOCC,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130102600A1,COC(=O)c1cc(N)ccn1.O=C(Cl)c1ccccc1>>COC(=O)c1cc(NC(=O)c2ccccc2)ccn1,,c1ccncc1,,CN(C)c1ccccn1,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(-c2ccc(OCC(C)(C)O)cc2)c2ccnn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(-c2ccc(OCC(C)(C)O)cc2)c2ccnn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20040138213A1,C1CCOC1.COc1cccc2c1CCCC2=O>>COc1cccc2c1CCCC2=C1CC1,,C1CCOC1,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US20100093757A1,CCOC[C@H](O)C(=O)Nc1cnc(C)cn1.FC(F)(F)c1ccccc1-n1ncc2c(Cl)ncnc21>>CCOC[C@H](Oc1ncnc2c1cnn2-c1ccccc1C(F)(F)F)C(=O)Nc1cnc(C)cn1,,C1CCOC1,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20090118296A1,CC(C)(C)OC(=O)N1CC[C@H](O)C1.Oc1ccccc1C(F)(F)F>>CC(C)(C)OC(=O)N1CC[C@H](Oc2ccccc2C(F)(F)F)C1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150336949A1,CC(C)(C)OC(=O)N1CCC(c2ccc(-c3cnc4[nH]cc(-c5cnn(Cc6cccc(F)c6)c5)c4c3)cc2F)CC1>>Fc1cccc(Cn2cc(-c3c[nH]c4ncc(-c5ccc(C6CCNCC6)c(F)c5)cc34)cn2)c1,,ClCCl,O=C(O)C(F)(F)F,,,test
US08853193B2,CS(N)(=O)=O.Cc1c(C(=O)O)sc2ncnc(Nc3ccc(F)cc3OC(CF)CF)c12>>Cc1c(C(=O)NS(C)(=O)=O)sc2ncnc(Nc3ccc(F)cc3OC(CF)CF)c12,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20110070317A1,CC(C)(C)OC(=O)N[C@@H]1CCCNC1.O=C(Nc1c[nH]c2ncc(Br)c(F)c12)c1ncccn1>>CC(C)(C)OC(=O)N[C@@H]1CCCN(c2c(Br)cnc3[nH]cc(NC(=O)c4ncccn4)c23)C1,,CCCCO,,,,test
US20090143448A1,CCc1sc(N)nc1C.COCCc1sc(S(N)(=O)=O)cc1C.O=C(Cl)Oc1ccccc1>>CCc1sc(NC(=O)NS(=O)(=O)c2cc(C)c(CCOC)s2)nc1C,,CC#N,,CCN(CC)CC,,test
US20100093757A1,CC(C)(C)[Si](OCCOC[C@H](O)C(=O)Nc1ccc(Cl)cn1)(c1ccccc1)c1ccccc1.Clc1ccccc1-n1nnc2c(Cl)ncnc21>>CC(C)(C)[Si](OCCOC[C@H](Oc1ncnc2c1nnn2-c1ccccc1Cl)C(=O)Nc1ccc(Cl)cn1)(c1ccccc1)c1ccccc1,,C1CCOC1,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20050124605A1,CI.COc1ccc2c(c1)NC(=O)CN=C2c1ccccc1>>COc1ccc2c(c1)N(C)C(=O)CN=C2c1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US05281571,CCOC(=O)C(C)Oc1cc(-c2nn(C)c(C(F)(F)F)c2Cl)c(F)cc1Cl>>CC(Oc1cc(-c2nn(C)c(C(F)(F)F)c2Cl)c(F)cc1Cl)C(=O)O,,C1COCCO1,O,Cl,[Na+].[OH-],test
US20160222047A1,COC1(c2ccc(Cl)c(Cc3ccc4c(c3)OCCO4)c2)O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>COC1(c2ccc(Cl)c(Cc3ccc4c(c3)OCCO4)c2)O[C@H](CO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,,CO,,CC(=O)Cl,,test
US05750531,CCc1cc(Cl)nc(N2CCc3ccccc3C2C)n1.Cc1cc(F)ccc1N>>CCc1cc(Nc2ccc(F)cc2C)nc(N2CCc3ccccc3C2C)n1.Cl,,CN(C)C=O,,,,test
US20130018034A1,CC(C)N.O=C(O)c1ccc(Br)cc1>>CC(C)NC(=O)c1ccc(Br)cc1,,ClCCl,,O=S(Cl)Cl,,test
US20150182537A1,CC(C)(C)OC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)O.Cn1nccc1Nc1nccc(-c2cc(F)[nH]c(=NN)c2)n1>>Cn1nccc1Nc1nccc(-c2cc(F)[nH]c(=NNC(=O)[C@@H](Cc3ccc(Cl)cc3)NC(=O)OC(C)(C)C)c2)n1,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20140371199A1,CC(=O)Nc1cc(Br)ccc1C(=O)N1CCC(N(C)C(=O)OC(C)(C)C)CC1.CC1(C)OB(c2ccc3ncc(-c4ccc(C#N)cc4)n3c2)OC1(C)C>>CC(=O)Nc1cc(-c2ccc3ncc(-c4ccc(C#N)cc4)n3c2)ccc1C(=O)N1CCC(N(C)C(=O)OC(C)(C)C)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20090018103A1,CC(C)(C)OC(=O)N[C@H](CO)CC1CCC(O[Si](C)(C)C(C)(C)C)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N[C@H](COS(C)(=O)=O)CC1CCC(O[Si](C)(C)C(C)(C)C)CC1,,ClCCl,,CCN(CC)CC,O,test
US04303660,CC(C)=O.Nc1ccccc1-c1[nH]ncc1[N+](=O)[O-]>>CC1(C)Nc2ccccc2-c2c([N+](=O)[O-])cnn21,,CC(=O)O,,,,test
US20130172353A1,COC(=O)CCNC(=O)Nc1snc(-c2ccc([N+](=O)[O-])cc2)c1C(N)=O>>NC(=O)c1c(-c2ccc([N+](=O)[O-])cc2)nsc1NC(=O)NCCCO,,C1CCOC1,,CO,[BH4-].[Na+],test
US20100152160A1,CC(C)(C)OC(=O)N1CCC(COS(C)(=O)=O)(Cc2ccc(F)cc2)CC1.c1c[nH]cn1>>CC(C)(C)OC(=O)N1CCC(Cc2ccc(F)cc2)(Cn2ccnc2)CC1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110144334A1,CN(C)C=O.COCc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(=O)O>>COCc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(N)=O,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20150291640A1,CO/C=C(\C)C(=O)NC(=O)NC1CCCC(O[Si](C)(C)C(C)(C)C)C1>>Cc1cn(C2CCCC(O[Si](C)(C)C(C)(C)C)C2)c(=O)[nH]c1=O,,CCO,,N,,test
US06140351,Nc1ccc(Cl)cc1.O=C(Cl)c1cc(Cl)ccc1[N+](=O)[O-]>>O=C(Nc1ccc(Cl)cc1)c1cc(Cl)ccc1[N+](=O)[O-],,ClCCl,,CCN(CC)CC,,test
US20100278733A1,CC(=O)c1ccc(I)cc1.O=Cc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]>>O=C(C=Cc1ccc([N+](=O)[O-])cc1[N+](=O)[O-])c1ccc(I)cc1,,CCO,,[K+].[OH-],,test
US20110034464A1,CC(C)(C)OC(=O)NCc1cc(Cl)ccc1N1CCCC1=O.Cl>>Cl.NCc1cc(Cl)ccc1N1CCCC1=O,,CCOC(C)=O,,C1COCCO1,,test
US20090137561A1,CC(C)(C)[Si](C)(C)Oc1cccc(C(=O)CC2CC2)c1F.COC(=O)C[Si](C)(C)C>>COC(=O)C=C(CC1CC1)c1cccc(O[Si](C)(C)C(C)(C)C)c1F,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20090264445A1,Cc1cccc(B(O)O)c1F.OO>>Cc1cccc(O)c1F,,C1CCOC1,,CC(=O)O,,test
US05919431,CCOC(=O)CN1CCNCCN(CC(=O)OCC)CCN(CC(=O)OCC)CC1.CS(=O)(=O)N(Cc1ccccc1)CC1CO1>>CCOC(=O)CN1CCN(CC(=O)OCC)CCN(CC(O)CN(Cc2ccccc2)S(C)(=O)=O)CCN(CC(=O)OCC)CC1,,CCO,,,,test
US20150111910A1,Cc1ccc(Oc2ccc([N+](=O)[O-])cn2)cc1OC(F)(F)F>>Cc1ccc(Oc2ccc(N)cn2)cc1OC(F)(F)F,[Pd],C1CCOC1,,,,test
US20110224202A1,COC(C(=O)N(C)OC)c1ccc(N2CCOCC2)cc1>>COC(C=O)c1ccc(N2CCOCC2)cc1,,Cc1ccccc1,ClCCl,CC(C)C[AlH]CC(C)C,,test
US20120149691A1,NC(=O)c1cnn2cc([N+](=O)[O-])cc2c1NC1CCCC1>>NC(=O)c1cnn2cc(N)cc2c1NC1CCCC1,[Pd],CCO,CCOC(C)=O,,,test
US04181663,O=C(Cl)c1ccccc1.O=C(O)[C@@H]1CCCN1C(=O)CC[SeH]>>O=C([Se]CCC(=O)N1CCC[C@H]1C(=O)O)c1ccccc1,,c1ccncc1,,,,test
US05998433,CS(=O)(=O)OCCc1ccsc1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1CCc1ccsc1,,CN(C)C=O,,O,[K],test
US06232271B1,Cc1ccccc1.Cn1nc(-n2ncc(C#N)c2C=O)c(Cl)c1S(C)(=O)=O.OCCCO>>CCOC(OCC)c1c(C#N)cnn1-c1cc(SC)n(C)n1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20040092582A1,COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(Nc3cccnc3)c1)=NC(C)(C)C2.O=C=NS(=O)(=O)Cl>>COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(N(C(N)=O)c3cccnc3)c1)=NC(C)(C)C2,,C1CCOC1,O,CC(=O)O,[Na+].[OH-],test
US20090088429A1,CC(C)(C)OC(=O)N1CCC(Oc2c(Cl)cc3cnccc3c2Cl)CC1>>Clc1cc2cnccc2c(Cl)c1OC1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090082379A1,CC(=O)N1CC(C)(C)c2ccc(N3C(=O)NC(C)(C)C3=O)cc21.ClCc1ccnc(Cl)c1>>CC(=O)N1CC(C)(C)c2ccc(N3C(=O)N(Cc4ccnc(Cl)c4)C(C)(C)C3=O)cc21,,CN(C)C=O,O,[H-].[Na+],,test
US04289768,O=C(O)CCn1ccnc1.c1ccc2c(c1)Nc1ccccc1S2>>O=C(CCn1ccnc1)N1c2ccccc2Sc2ccccc21,,CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US06265415B1,CC(=O)C(C)Br.Nc1cc(Br)cnc1N>>Cc1nc2c(N)cc(Br)cn2c1C,,CCO,,,,test
US20080176872A1,C[C@H](N)c1ccc(F)cc1.O=[N+]([O-])c1ccc(Cl)nc1Nc1cc(C2CC2)[nH]n1>>C[C@H](Nc1ccc([N+](=O)[O-])c(Nc2cc(C3CC3)[nH]n2)n1)c1ccc(F)cc1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20160264567A1,CC(C)(C)OC(=O)NCc1cc(C(F)(F)F)nc(C2CC2)c1F.Cl>>Cl.NCc1cc(C(F)(F)F)nc(C2CC2)c1F,,C1COCCO1,,,,test
US04317817,C[C@@H](C=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C(C(=O)c5ccccc5)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C>>C[C@@H](CO)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C(C(=O)c5ccccc5)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,CCOCC,CO,[BH4-].[Na+],test
US20120245199A1,COCCn1ccc2ccnc(Cl)c21.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COCCn1cc(C(=O)C(F)(F)F)c2ccnc(Cl)c21,,CN(C)C=O,,,,test
US06180759B2,CCN(CC(=O)O)C(=O)OC(C)(C)C.CCO>>CCOC(=O)CN(CC)C(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US04587340,CCOC(=O)c1nc2cnc(Nc3ccccc3)nc2n(-c2ccccc2)c1=O>>COCC1CNc2nc(N)[nH]c(=O)c2N1,O=[Pt]=O,Cl,,O=C(O)C(F)(F)F,,test
US20070042398A1,CC1=Nc2ccccc2C1(C)C.O=[N+]([O-])O>>CC1=Nc2ccc([N+](=O)[O-])cc2C1(C)C,,O=S(=O)(O)O,,,,test
US06229055B1,C=O.CC#N.Nc1cc(O)ccc1F>>CN(C)c1cc(O)ccc1F,,CC#N,O,CC(=O)O,[BH3-]C#N.[Na+],test
US20140128424A1,CCOC(=O)c1c(C)nc2c(OCc3c(F)cccc3F)cc(C#C[Si](C)(C)C)cn12>>C#Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(C(=O)OCC)n2c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20070093479A1,C[Si](C)(C)CCOCn1nc(NC(=O)Nc2ccccc2)c2cc(-c3ccccc3)c(Cl)cc21>>O=C(Nc1ccccc1)Nc1n[nH]c2cc(Cl)c(-c3ccccc3)cc12,,CO,,Cl,,test
US20130338159A1,CS(=O)c1nccc(-c2cnc(NCC(C)(C)O)nc2CC2CC2)n1.NC1=CCC(=S(=O)=O)C=C1>>CC(C)(O)CNc1ncc(-c2ccnc(Nc3ccc(S(C)(=O)=O)cc3)n2)c(CC2CC2)n1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05445764,CCC[C@@H]1CC[C@@H](C2CC3(CC(=O)C3)C2)CC1.Fc1cc([Mg]Br)cc(F)c1F>>CCC[C@@H]1CC[C@@H](C2CC3(C2)CC(O)(c2cc(F)c(F)c(F)c2)C3)CC1,,CCOCC,,,,test
US20090247507A1,CC(C)(C)OC(=O)N1CCN(CC(=O)Nc2nccs2)CC1.CI>>CN(C(=O)CN1CCN(C(=O)OC(C)(C)C)CC1)c1nccs1,,CN(C)C=O,,[H-].[Na+],,test
US04145419,COC(=O)c1cn2c(n1)COc1ccccc1-2.O=[N+]([O-])O>>COC(=O)c1cn2c(n1)COc1ccc([N+](=O)[O-])cc1-2,,O,,O=S(=O)(O)O,,test
US20140315889A1,COC(=O)c1ccc(Cn2c3c(c4cc(F)ccc42)C(=O)N(CCO)CC3)cc1.OC[C@@H]1CCCN1>>COC(=O)c1ccc(Cn2c3c(c4cc(F)ccc42)C(=O)N(CCN2CCC[C@H]2CO)CC3)cc1,,CC#N,,CCN(C(C)C)C(C)C,CS(=O)(=O)Cl,test
US20140323305A1,CN.CO/N=C(\C=C(\C)COc1ccn(-c2ccc(Cl)cc2)n1)C(=O)OC>>CNC(=O)C(C=C(C)COc1ccn(-c2ccc(Cl)cc2)n1)=NOC,,C1CCOC1,,,,test
US05216026,NS(=O)(=O)C1CCCC1.O=C=Nc1ccc(Cl)cc1>>O=C(Nc1ccc(Cl)cc1)NS(=O)(=O)C1CCCC1,,CC(C)=O,,Cl,[Na+].[OH-],test
US04564694,CCCCCC1CCC(c2cc(CCCBr)ccc2C(=O)c2ccc(CCCBr)cc2C2CCC(CCCCC)CC2)CC1.CO.CO>>CCCCCC1CCC(c2cc(CCCOC)ccc2C(=O)c2ccc(CCCOC)cc2C2CCC(CCCCC)CC2)CC1,,CO,,C[O-].[Na+],,test
US03932461,CC(=O)CCc1ccc2c(c1)OCO2.Cl.NCCc1ccc(O)c(O)c1>>CC(CCc1ccc2c(c1)OCO2)NCCc1ccc(O)c(O)c1.Cl,O=[Pt],CCO,,O=C([O-])O.[Na+],,test
US20030199520A1,COc1cc(C)c(S(=O)(=O)N(Cc2ccc3c(c2)OCO3)[C@H](CNS(C)(=O)=O)C(=O)OC(C)(C)C)c(C)c1>>COc1cc(C)c(S(=O)(=O)N(Cc2ccc3c(c2)OCO3)[C@H](CNS(C)(=O)=O)C(=O)O)c(C)c1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20070043011A1,CC(=O)c1ccc(C(F)(F)F)cn1.Cc1cc(I)ccc1NC(=O)OC(C)(C)C>>Cc1cc(C(C)(O)c2ccc(C(F)(F)F)cn2)ccc1NC(=O)OC(C)(C)C,,COC(C)(C)C,,[Li]CCCC,[Cl-].[NH4+],test
US04810636,Cc1ccc(S(=O)(=O)N[C@@H](C)C(=O)O)cc1.O=S(Cl)Cl>>Cc1ccc(S(=O)(=O)N[C@@H](C)C(=O)Cl)cc1,,CCCCCC,,,,test
US20120010190A1,CNCCO.Cc1cc(/C(C[C@H](c2ccc(C(=O)O)cc2)c2ccccc2C)=N/O)ccn1>>Cc1cc(/C(C[C@H](c2ccc(C(=O)N(C)CCO)cc2)c2ccccc2C)=N/O)ccn1,,C1CCOC1,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US20100056518A1,CCOC(=O)CN[C@@H]1CC[C@H](Oc2cc3cc[nH]c(=O)c3cc2Cl)CC1>>O=C(O)CN[C@@H]1CC[C@H](Oc2cc3cc[nH]c(=O)c3cc2Cl)CC1,,CO,,,,test
US20070032515A1,BrCCBr.COC(=O)c1cccc(OC(=O)c2ccccc2)c1O>>COC(=O)c1cccc(OC(=O)c2ccccc2)c1OCCBr,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110152287A1,Brc1nc2ccccc2s1.CC(C)(C)OC(=O)NCCN>>CC(C)(C)OC(=O)NCCNc1nc2ccccc2s1,,ClC(Cl)Cl,,,,test
US06235789B1,CCOP(=O)(CC#N)OCC.COc1ccc2c(c1)C(=O)CC2>>COc1ccc2c(c1)C(=CC#N)CC2,,C1CCOC1,,O,[H-].[Na+],test
US20130143870A1,COc1cc(C2=CCN(C(=O)OC(C)(C)C)CC2)ncn1>>COc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ncn1,[Pd],CO,,[H][H],,test
US20090131402A1,O=C1c2ccnc(Cl)c2OCCN1Cc1ccccc1>>Clc1nccc2c1OCCN(Cc1ccccc1)C2,,C1CCOC1,,CO,,test
US20050075516A1,COC(=O)c1cc(OC)c2c(c1)OCO2>>COc1cc(CO)cc2c1OCO2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080194549A1,CC(=O)OC(C)=O.CC(C)(N)CC(=O)O>>CC(=O)NC(C)(C)CC(=O)O,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,CCOC(C)=O,test
US20150225449A1,COc1ccc2c(Br)cccc2c1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)[C@H](C)N(C(=O)CS(C)(=O)=O)c2cc(C#N)ccc21.O=C(O)C(F)(F)F>>CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3c(Br)cccc23)c2ccc(C#N)cc2N(C(=O)CS(C)(=O)=O)[C@H]1C.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20120059028A1,CCN(CC)C(=O)Cl.Oc1cccc(Cl)c1>>CCN(CC)C(=O)Oc1cccc(Cl)c1,,C1CCOC1,,[H-].[Na+],,test
US20140329876A1,Cc1c(C2=NN3CC[C@H](O[Si](C)(C)C(C)(C)C)[C@H]3[C@@H]2OCC2CC2)ccc(C#N)c1Cl>>Cc1c(C2=NN3CC[C@H](O)[C@H]3[C@@H]2OCC2CC2)ccc(C#N)c1Cl,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20030166637A1,CC1CN(C(=O)OC(C)(C)C)CCN1c1ccc2ccccc2n1>>CC1CNCCN1c1ccc2ccccc2n1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20090018103A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)NC(CN)CC2(O)CCCCC2)cc1>>Cc1ccc(S(=O)(=O)NC(CNC(=O)OC(C)(C)C)CC2(O)CCCCC2)cc1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20050277630A1,CCCC(=O)OCC1CN(c2ccc3c(c2)OCCCC3=O)C(=O)O1>>O=C1CCCOc2cc(N3CC(CO)OC3=O)ccc21,,CCCCCCC,CCOC(C)=O,CO,[K+].[OH-],test
US20100173933A1,CC(=O)Cl.Nc1ccc(Oc2ccccc2)cc1>>CC(=O)Nc1ccc(Oc2ccccc2)cc1,,ClCCl,,CCN(CC)CC,O,test
US20040097526A1,C[Si](C)(C)CCOCn1nccc1-c1nc(N)nc2c1nnn2Cc1cccc([N+](=O)[O-])c1.Cl>>Cl.Nc1nc(-c2cc[nH]n2)c2nnn(Cc3cccc([N+](=O)[O-])c3)c2n1,,C1COCCO1,CO,,,test
US06593300B1,COC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccccc1)C(C)C>>COC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C,[Pd],CN(C)C=O,,,,test
US20120264749A1,CCc1cnc(C2CN(CC(F)F)CC3(CCN(C(=O)OC(C)(C)C)CC3)O2)o1.Cl>>CCc1cnc(C2CN(CC(F)F)CC3(CCNCC3)O2)o1.Cl,,ClCCl,,,,test
US05641789,COc1ccc2c(c1)C(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(C)(C)O2>>COc1ccc2c(c1)C(=O)C(Cc1cccc(N)c1)C(C)(C)O2,[Pd],C1CCOC1,CCOC(C)=O,[H][H],,test
US20050197350A1,CN(C)c1cc(Cl)nc2ccccc12.N[C@H]1CC[C@@H](CNC(=O)OCc2ccccc2)CC1>>CN(C)c1cc(N[C@@H]2CC[C@H](CNC(=O)OCc3ccccc3)CC2)nc2ccccc12,,CCCCO,,O=C([O-])O.[Na+],,test
US20100168182A1,O=C1Cc2ccc(Nc3cccc(NC(=O)Nc4cc(F)c(F)cc4F)c3)cc2N1.O=Cc1ccc[nH]1>>O=C(Nc1cccc(Nc2ccc3c(c2)NC(=O)C3=Cc2ccc[nH]2)c1)Nc1cc(F)c(F)cc1F,,CCO,,C1CCNCC1,,test
US20080275046A1,CCOC(=O)Cc1sc(-c2ccc(OCCCCl)cc2)nc1C>>Cc1nc(-c2ccc(OCCCCl)cc2)sc1CC(=O)O,,CCO,,Cl,[Na+].[OH-],test
US06608072B1,CC(C)(C)OC(=O)N1CCN(c2ccc3[nH]c(-c4ccc(F)cc4)nc3n2)CC1.CSc1nccc(I)n1>>CSc1nccc(-n2c(-c3ccc(F)cc3)nc3nc(N4CCN(C(=O)OC(C)(C)C)CC4)ccc32)n1,,CN(C)C=O,Cc1ccccc1,,,test
US20090131659A1,COC(=O)c1ccc(C(=O)NN2CCOCC2)s1.NN>>NNC(=O)c1ccc(C(=O)NN2CCOCC2)s1,,CCO,,O,,test
US04800207,CC(=O)c1ccc(C)cc1.O=Cc1ccc[nH]1>>Cc1ccc(C(=O)C=Cc2ccc[nH]2)cc1,,O,,[K+].[OH-],,test
US20110020278A1,CC(C)(C)C#Cc1cc(I)c(C(=O)O)s1.ClCCl>>COC(=O)c1sc(C#CC(C)(C)C)cc1I,,ClCCl,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20110301197A1,CCOC(=O)c1csc(C2(F)CCN(C(=O)Cn3nc(C(F)F)cc3C(F)F)CC2)n1>>O=C(O)c1csc(C2(F)CCN(C(=O)Cn3nc(C(F)F)cc3C(F)F)CC2)n1,,C1CCOC1,O,[Li+].[OH-],,test
US20130109672A1,Cc1ccc(N)cc1C.O=C1CCc2cc(C(=O)O)ccc2N1>>Cc1ccc(NC(=O)c2ccc3c(c2)CCC(=O)N3)cc1C,,CN(C)C=O,,ClCCCl,,test
US20130317026A1,Cc1cc(C)c(CNC(=O)c2cc(Br)nc3c2cnn3C(C)C)c(=O)[nH]1.OB(O)c1cnn(CCN2CCOCC2)c1>>Cc1cc(C)c(CNC(=O)c2cc(-c3cnn(CCN4CCOCC4)c3)nc3c2cnn3C(C)C)c(=O)[nH]1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US20060135447A1,N#Cc1cc([N+](=O)[O-])ccc1F.c1nc[nH]n1>>N#Cc1cc([N+](=O)[O-])ccc1-n1cncn1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20030165623A1,CCCCCCBr.CCc1nc(C)c[nH]1>>CCCCCCn1cc(C)nc1CC,,C1CCOC1,,[H-].[Na+],,test
US20120083514A1,CC1(C)NC(=O)N(c2ccc([N+](=O)[O-])c(C(F)(F)F)c2)C1=O.CS(=O)(=O)OCCCCCCCCCSCCCC(F)(F)C(F)(F)F>>CC1(C)C(=O)N(c2ccc([N+](=O)[O-])c(C(F)(F)F)c2)C(=O)N1CCCCCCCCCSCCCC(F)(F)C(F)(F)F,,CN(C)C=O,,O,[H-].[Na+],test
US20020115711A1,COC(=O)c1cc(C(C)=O)ccc1OS(=O)(=O)C(F)(F)F.COc1ccc(B(O)O)c(OC)c1>>COC(=O)c1cc(C(C)=O)ccc1-c1ccc(OC)cc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20070225308A1,C=CC[Sn](CCCC)(CCCC)CCCC.COc1c(Br)cc(-c2cccc(Cl)c2)c2cnc(N(C)C)nc12>>C=CCc1cc(-c2cccc(Cl)c2)c2cnc(N(C)C)nc2c1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,,test
US05629293,COC1=N[C@H](C(C)C)C(OC)=NC1.COCBr>>COC[C@@H]1N=C(OC)[C@@H](C(C)C)N=C1OC,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20160272595A1,CCS(=O)(=O)n1cccc1CNC(=O)OC(C)(C)C.Cl>>CCS(=O)(=O)n1cccc1CN.Cl,,CCOC(C)=O,,,,test
US20090054431A1,CC(=O)Nc1ccc(F)cc1C(F)(F)F.O=[N+]([O-])O>>CC(=O)Nc1c([N+](=O)[O-])cc(F)cc1C(F)(F)F,,O=S(=O)(O)O,,,,test
US05441984,COCOc1c(-c2sccc2C)cc(CN)cc1C(C)(C)C.CSc1ccc(N(C(=O)[O-])c2ccc([N+](=O)[O-])cc2)cc1>>CSc1ccc(NC(=O)NCc2cc(-c3sccc3C)c(O)c(C(C)(C)C)c2)cc1,,Cc1ccccc1,,,,test
US20160152624A1,COc1ccc(B(O)O)cc1Cl.Cc1nc(Cl)nc2c1C(C)CN2c1ccc(CC(=O)OC(C)(C)C)cc1>>COc1ccc(-c2nc(C)c3c(n2)N(c2ccc(CC(=O)OC(C)(C)C)cc2)CC3C)cc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US20030109706A1,CN(CC1CCN(C(=O)OC(C)(C)C)CC1)C(=O)OCc1ccccc1>>CNCC1CCN(C(=O)OC(C)(C)C)CC1,,CCO,CCOC(C)=O,,,test
US20090192176A1,Nc1nc(-c2cccc(O)c2)nc(C(=O)C2CCC=CO2)c1[N+](=O)[O-]>>Nc1nc(-c2cccc(O)c2)nc(C(=O)C2CCC=CO2)c1N,[Ni],CO,,NN,,test
US20050282808A1,CC(C)(C)OC(=O)CBr.N#Cc1ccccc1O>>CC(C)(C)OC(=O)COc1ccccc1C#N,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04587256,O=C1NC(=O)C2(CCOc3c([N+](=O)[O-])cc(F)cc32)S1>>Nc1cc(F)cc2c1OCCC21SC(=O)NC1=O,O=[Pt],CCO,,ClC(Cl)Cl,,test
US20080318929A1,Cc1c(CNc2ncc([N+](=O)[O-])c(N3CCc4nc[nH]c4CC3)n2)cccc1-c1cccc(CNC(=O)OC(C)(C)C)c1>>Cc1c(CNc2ncc([N+](=O)[O-])c(N3CCc4nc[nH]c4CC3)n2)cccc1-c1cccc(CN)c1,,ClCCl,,C1COCCO1,Cl,test
US20080021069A1,CCOC(=O)c1ccc(-n2c(SCc3ccc(Cl)cc3)nc3ccc(Cl)cc32)cc1>>O=C(O)c1ccc(-n2c(SCc3ccc(Cl)cc3)nc3ccc(Cl)cc32)cc1,,CCO,,C1CCOC1,[Na+].[OH-],test
US20120034660A1,CCOC(=O)C(NC(=O)OCc1ccccc1)C(=O)OCC.O=C(CBr)OCc1ccccc1>>CCOC(=O)C(CC(=O)OCc1ccccc1)(NC(=O)OCc1ccccc1)C(=O)OCC,,CN(C)C=O,,Cl,[H-].[Na+],test
US20140336377A1,COc1nc(OCC(F)(F)F)ccc1CN1C(=O)c2ccccc2C1=O>>COc1nc(OCC(F)(F)F)ccc1CN,,CO,,NN,O,test
US06187802B1,O=C(CBr)C1(c2ccc3ccccc3c2)CCC1.S=C1NCCN1>>Br.C1=C(C2(c3ccc4ccccc4c3)CCC2)N2CCN=C2S1,,CC(=O)O,,CCO,,test
US20110071150A1,Cn1nc(C(F)(F)F)cc1-c1ccc2[nH]c(Br)cc2c1.OB(O)c1cccc(Cl)c1Cl>>Cn1nc(C(F)(F)F)cc1-c1ccc2[nH]c(-c3cccc(Cl)c3Cl)cc2c1,,C1COCCO1,,,,test
US20060019985A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1cncc(C2CCNC2)c1>>CC(C)(C)OC(=O)N1CCC(c2cccnc2)C1,,CCO,O,[Na+].[OH-],,test
US20130090323A1,COc1cc(B(O)O)ccc1C#N.Nc1cc(N2CCOCC2)ncc1Br>>COc1cc(-c2cnc(N3CCOCC3)cc2N)ccc1C#N,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20160185785A1,COC(=O)c1ccc2c(c1)CCN(c1ccccc1)C2>>O=C(O)c1ccc2c(c1)CCN(c1ccccc1)C2,,C1CCOC1,,Cl,[Na+].[OH-],test
US20030134838A1,CNc1nc(Nc2ccc3c(c2)CCN(C(=O)C(F)(F)F)CC3)ncc1[N+](=O)[O-]>>CNc1nc(Nc2ccc3c(c2)CCNCC3)ncc1[N+](=O)[O-],,O,,C1CCOC1,[Na+].[OH-],test
US04691027,CN(C)CCO.COCOc1c(C)c(C)c2c(c1C)SC(CCCI)O2>>COCOc1c(C)c(C)c2c(c1C)SC(CCCOCCN(C)C)O2,,CN(C)C=O,,O,[H-].[Na+],test
US20110092504A1,CC1(C)OB(c2ccc3ncccc3c2)OC1(C)C.COc1ccc(S(=O)(=O)Nc2cc(Br)cnc2Cl)cc1>>COc1ccc(S(=O)(=O)Nc2cc(-c3ccc4ncccc4c3)cnc2Cl)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20070244136A1,CNCCO.O=c1[nH]cnc2cccc(F)c12>>CNCCOc1cccc2nc[nH]c(=O)c12,,CC(=O)N(C)C,,CO,[H-].[Na+],test
US20080008682A1,CCOP(=O)(COC(COc1ccccc1)Cn1cnc2c(N)nc(OCCOC)nc21)OCC.O=C1CCC(=O)N1Br>>CCOP(=O)(COC(COc1ccccc1)Cn1c(Br)nc2c(N)nc(OCCOC)nc21)OCC,,CC#N,,,,test
US05541324,CCOC(=O)CN.O=[N+]([O-])c1ccc(F)cc1F>>CCOC(=O)CNc1cc(F)ccc1[N+](=O)[O-],,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20050153978A1,CCNc1ccc(F)cc1NC(=O)OC(C)(C)C.Cc1nc(O)c2nonc2n1>>CCn1c(-c2nonc2N)nc2cc(F)ccc21,,CC(=O)O,,,,test
US20120258973A1,CNN.N#CCC(=O)c1ccccc1>>Cn1nc(-c2ccccc2)cc1N,,CO,,,,test
US03976653,COc1ccc(C[C@@H]2NCCC[C@@H]2C(=O)O)cc1.ClCc1ccccc1>>COc1ccc(C[C@H]2[C@@H](C(=O)O)CCCN2Cc2ccccc2)cc1.Cl,,CN(C)C=O,,Br,O=C([O-])O.[Na+],test
US20160272621A1,CC(=O)c1cc(Cl)ncc1N.CC(O)C(C)O>>CC1OC(C)(c2cc(Cl)ncc2N)OC1C,,CCOC(C)=O,Cc1ccccc1,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20060128635A1,Br[Mg]c1ccccc1.CC(C)c1c(C=O)c(OCc2ccccc2)nn1C(C)C>>CC(C)c1c(C(O)c2ccccc2)c(OCc2ccccc2)nn1C(C)C,,C1CCOC1,,O,[Cl-].[NH4+],test
US04921939,CC(C)(C)OC(=O)CN.N#Cc1ccc(N=C=S)cc1>>CC(C)(C)OC(=O)CNC(=S)Nc1ccc(C#N)cc1,,CC#N,,,,test
US06147088,Cc1cc(C)cc(CC(=O)O)c1.O=C(Cl)C(=O)Cl>>Cc1cc(C)cc(CC(=O)Cl)c1,,CN(C)C=O,,,,test
US20130165426A1,CCOC(=O)c1ccc([N+](=O)[O-])c(NCCCN2CCCCC2)n1>>O=C(O)c1ccc([N+](=O)[O-])c(NCCCN2CCCCC2)n1,,CO,,C1CCOC1,[Li+].[OH-],test
US20130217666A1,C#C[Si](CC)(CC)CC.CC(=O)CF>>CC[Si](C#CC(C)(O)CF)(CC)CC,,C1CCOC1,,[Li]CCCC,,test
US04310538,CC(C)(C)[Si](C)(C)N1C(=O)CC1CC(O)CC(=O)OCc1ccccc1>>CC(C)(C)[Si](C)(C)N1C(=O)CC1CC(O)CC(=O)O,[Pd],CCO,,,,test
US20160185785A1,O=Cc1cccc(-n2ncc3c(=O)[nH]cnc32)c1>>O=c1[nH]cnc2c1cnn2-c1cccc(CO)c1,,CO,,[BH4-].[Na+],,test
US20130210811A1,OC1(C(F)(F)F)CCC2(CC1)OCCO2>>O=C1CCC(O)(C(F)(F)F)CC1,,C1CCOC1,,Cl,,test
US20100215579A1,C=O.Nc1ccc(-c2ccc3cc(OCCOCCOCCF)ccc3c2)cc1.[BH3-]C#N>>CN(C)c1ccc(-c2ccc3cc(OCCOCCOCCF)ccc3c2)cc1,,CC(=O)O,,[Na+].[OH-],,test
US20150152095A1,Cc1ccc(C2CCCN2)cc1.Cl.N=C(N)n1cccn1>>Cc1ccc(C2CCCN2C(=N)N)cc1.Cl,,CC#N,,CCN(C(C)C)C(C)C,,test
US20110160198A1,COC(=O)[C@H](Cc1ccc(-c2ccnc(C)c2C)cc1)NC(=O)[C@@H]1Cc2cc3c(cc2CN1C(=O)OC(C)(C)C)O[C@@H](c1ccc(O)cc1)CO3.C[C@@H](N=C=O)c1ccccc1.OCCc1ccc(Cl)cc1>>Cc1nccc(-c2ccc(C[C@H](NC(=O)[C@@H]3Cc4cc5c(cc4CN3C(=O)N[C@H](C)c3ccccc3)O[C@@H](c3ccc(OCCc4ccc(Cl)cc4)cc3)CO5)C(=O)O)cc2)c1C,,ClCCl,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06528223B1,CCCCN(CCCC)C(=S)NC(=O)c1cccc(OC)c1.O=C(O)CCl>>CCCCN(CCCC)c1nc(-c2cccc(OC)c2)cs1,,O,,[Na+].[OH-],,test
US20070197533A1,O=C(OCc1ccccc1)c1ccc(OCc2ccccc2)cc1OCc1ccccc1>>O=C(O)c1ccc(OCc2ccccc2)cc1OCc1ccccc1,,CO,,Cl,[Na+].[OH-],test
US20110136764A1,CCOP(=O)(Cc1ccc(Nc2ncc(C(F)(F)F)c(Nc3cccc4c3C(=O)N(C)C4)n2)c(OC)c1)OCC>>CCOP(=O)(O)Cc1ccc(Nc2ncc(C(F)(F)F)c(Nc3cccc4c3C(=O)N(C)C4)n2)c(OC)c1,,Cl,,,,test
US20080171743A1,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.Nc1ccon1.O=C(Cl)Oc1ccccc1>>CC1(C)OB(c2ccc(NC(=O)Nc3ccon3)cc2)OC1(C)C,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20080286607A1,ClC(=NN=C(Cl)c1ccccc1)c1ccccc1.Nc1ccc(Br)cc1>>Brc1ccc(-n2c(-c3ccccc3)nnc2-c2ccccc2)cc1,,Cc1ccccc1,,CN(C)c1ccccc1,,test
US20150175567A1,O=C1CCc2ccc(Br)cc21.OB(O)c1cccc(F)c1>>O=C1CCc2ccc(-c3cccc(F)c3)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,Cc1ccccc1,O=C([O-])[O-].[Cs+].[Cs+],test
US20100216788A1,CC(C)(C)NC(=O)c1cccc(Cn2ccc3cc(N)ccc32)c1.O=C(OCCn1ccc2ncnc(Cl)c21)c1ccccc1>>CC(C)(C)NC(=O)c1cccc(Cn2ccc3cc(Nc4ncnc5ccn(CCO)c45)ccc32)c1,,CC(C)O,,O=C([O-])O.[Na+],,test
US04963566,COc1ccc2nc(SCc3cccc4c3N(C)CCC4)[nH]c2c1.O=C(OO)c1cccc(Cl)c1>>COc1ccc2nc(S(=O)Cc3cccc4c3N(C)CCC4)[nH]c2c1,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US04144341,C=CCBr.O=c1[nH]c2ccc(F)nc2n1-c1ccc2c(c1)OCO2>>C=CCn1c(=O)n(-c2ccc3c(c2)OCO3)c2nc(F)ccc21,,CC(C)=O,,[K+].[OH-],,test
US20140121206A1,COc1ccc(CN2C[C@@]3(CCC[C@](C)(Cn4cnc5ccc(C#N)cc54)C3)OC2=O)cc1>>C[C@]1(Cn2cnc3ccc(C#N)cc32)CCC[C@@]2(CNC(=O)O2)C1,,O=C(O)C(F)(F)F,,,,test
US20110224188A1,CC(C)(C)OC(=O)CN.C[C@@]1(Cc2ccc(OC(F)(F)F)cc2)C(=O)N(c2cc(Cl)cc(Cl)c2)c2ncc(C(=O)O)n21>>CC(C)(C)OC(=O)CNC(=O)c1cnc2n1[C@](C)(Cc1ccc(OC(F)(F)F)cc1)C(=O)N2c1cc(Cl)cc(Cl)c1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US05252538,CCOC(=O)c1cc2c(ccn2OC)nc1C(=O)OCC.O=C1CCC(=O)N1Cl>>CCOC(=O)c1cc2c(nc1C(=O)OCC)c(Cl)cn2OC,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20140065103A1,COC(=O)c1sc(C#CC(C)(C)C)cc1N.Cn1cc(C=O)cn1>>COC(=O)c1sc(C#CC(C)(C)C)cc1NCc1cnn(C)c1,,ClCCCl,,CC(=O)O,O=C([O-])O.[Na+],test
US20100210680A1,C[C@]12CN(Cc3ccccc3)C(=O)[C@@H]1c1cccc(Cl)c1CO2>>C[C@]12CN(Cc3ccccc3)C[C@@H]1c1cccc(Cl)c1CO2,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US05039685,ClCCBr.ON=C(c1ccccc1)c1ccccc1>>ClCCON=C(c1ccccc1)c1ccccc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04013582,O=C(O)c1ccc(O)cc1>>O=C(O)C1CCC(O)CC1,O=[Pt],CCO,,[K+].[OH-],,test
US04364956,CCOC(=O)c1cc(=O)c(Sc2ccc(Cl)cc2)co1>>O=C(O)c1cc(=O)c(Sc2ccc(Cl)cc2)co1,,C1COCCO1,Cl,,,test
US20160115158A1,COc1cc(Cl)nnc1N.O=S(=O)(Cl)c1cc(Cl)sc1Cl>>COc1cc(Cl)nnc1NS(=O)(=O)c1cc(Cl)sc1Cl,,ClCCl,,O,c1ccncc1,test
US05550251,CC(=O)OC(C)=O.NCCCCCO>>CC(=O)NCCCCCO,,CO,,CCN(CC)CC,,test
US20100048636A1,CC(C)(C)OC(=O)N[C@H](CO)CC1CCCCO1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N[C@H](COS(C)(=O)=O)CC1CCCCO1,,ClCCl,,CCN(CC)CC,,test
US20150264932A1,O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OCCN(CCO)Cc1ccccc1>>O=C1OCCN(Cc2ccccc2)CCO1,,C1CCOC1,,CCN(CC)CC,,test
US06395718B1,C=C(CCC(=O)OCc1ccccc1)C(=O)OCc1ccccc1.CC(C)=O.SCc1ccccc1>>O=C(CCC(CS(=O)Cc1ccccc1)C(=O)OCc1ccccc1)OCc1ccccc1,CN(C)c1ccncc1,,,,,test
US20120309724A1,CCOC(=O)[C@H](O)[C@H](N)Cc1ccccc1.O=C(O)c1ccc(Cl)nn1>>CCOC(=O)[C@H](O)[C@@H](Cc1ccccc1)NC(=O)c1ccc(Cl)nn1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05180734,O=[N+]([O-])C(Br)C(Br)c1ccc(Cl)cc1>>O=[N+]([O-])C(Br)=Cc1ccccc1,,C1CCCCC1,,c1ccncc1,,test
US20130022665A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCCCNCCCO>>CC(C)(C)OC(=O)N(CCCO)CCCO,,ClCCl,,,,test
US20160002175A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cccc(-c2cc(NC3CCCCC3N)nc(N)n2)c1C>>Cc1cccc(-c2cc(NC3CCCCC3NC(=O)OC(C)(C)C)nc(N)n2)c1C,,C1CCOC1,,CCN(CC)CC,,test
US20120220552A1,CCCCCCCCOc1ccc(C2CNCCO2)cc1.ClCCOC1CCCCO1>>CCCCCCCCOc1ccc(C2CN(CCOC3CCCCO3)CCO2)cc1,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20070060577A1,CN1CCNCC1.O=[N+]([O-])c1ccc(CCBr)cc1>>CN1CCN(CCc2ccc([N+](=O)[O-])cc2)CC1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04208202,Cc1cc(C)c(N2CCCCC2=O)cc1N.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1cc(C)c(N2CCCCC2=O)cc1NS(=O)(=O)C(F)(F)F,,ClC(Cl)Cl,,CCN(CC)CC,,test
US04868194,COc1ccc(CCN2CCC(C(=O)c3ccc(-n4ccnc4)cc3)CC2)cc1OC>>COc1ccc(CCN2CCC(C(O)c3ccc(-n4ccnc4)cc3)CC2)cc1OC,,CO,,O,[BH4-].[Na+],test
US20120196864A1,C=O.CNC1=NC(=O)S/C1=C\c1ccc(OCc2ccc(C(F)(F)F)cc2C(F)(F)F)c(N)c1>>CNC1=NC(=O)S/C1=C\c1ccc(OCc2ccc(C(F)(F)F)cc2C(F)(F)F)c(NC)c1,CC(=O)O,C1CCOC1,CC#N,[BH3-]C#N.[Na+],,test
US20080182851A1,O=C(O)C(F)(F)F.O=C(c1ccccc1C(F)(F)F)N1CCN(c2ccc(I)nn2)CC1>>Fc1ccccc1O[C@H]1CCNC1,,ClCCl,,,,test
US05360802,CC(C)C(=O)NS(=O)(=O)c1cccc([N+](=O)[O-])c1>>CC(C)C(=O)NS(=O)(=O)c1cccc(N)c1,[Pd],CCO,O,,,test
US20060003990A1,CCOC(=O)N1CCc2sc(C(F)(F)F)c(Cl)c2CC1>>FC(F)(F)c1sc2c(c1Cl)CCNCC2,,ClCCl,,C[Si](C)(C)I,,test
US20040122244A1,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)Nc3ccccc3C(F)(F)F)c2)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2ccc(O)c(C(=O)Nc3ccccc3C(F)(F)F)c2)=C(C)C1=O,,CO,O,O=C([O-])O.[Na+],,test
US20080227983A1,CC(C)(C(=O)O)c1ccc(C(=O)CCCC2CCN(C(O)(c3ccccc3)c3ccccc3)CC2)cc1>>CC(C)(C(=O)O)c1ccccc1,,CO,,[BH4-].[Na+],,test
US20120041030A1,CCCOc1cc[nH]c(=O)c1C.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCCOc1cc[nH]c(=S)c1C,,Cc1ccccc1,,,,test
US20040077605A1,N#Cc1ccc([N+](=O)[O-])c2nccnc12>>N#Cc1ccc(N)c2c1NCCN2,[Pd],CCO,CCOC(C)=O,[H][H],,test
US06093732,CCOC=C(C(=O)OCC)C(=O)OCC.Nc1ccc(I)cc1>>CCOC(=O)c1cnc2ccc(I)cc2c1O,,CCO,,c1ccc(Oc2ccccc2)cc1,,test
US20100056521A1,CCOC(=O)c1ccc(-n2cc(C#N)c3cc(O)c(Cl)cc32)cc1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1ccc(-n2cc(C#N)c3cc(OS(=O)(=O)C(F)(F)F)c(Cl)cc32)cc1,,ClCCl,O,Cl,c1ccncc1,test
US20130324404A1,COCON1C(=O)C(c2cc(C)ccc2C)C(=O)C12CCN(OC)CC2.O=S(=O)(Cl)Cl>>COCON1C(=O)C(Cl)(c2cc(C)ccc2C)C(=O)C12CCN(OC)CC2,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20100298343A1,BrCc1ccccc1.CCOC(=O)Cc1[nH]c2ccc(OC)cc2c1SC(C)(C)C>>CCOC(=O)C(Cc1ccccc1)c1[nH]c2ccc(OC)cc2c1SC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US06201121B1,CCO.O=C(O)Cn1c(=O)[nH]c(=O)c2ccc(Cl)cc21>>CCOC(=O)Cn1c(=O)[nH]c(=O)c2ccc(Cl)cc21,O=S(=O)(O)O,,,O=S(Cl)Cl,,test
US05492921,CC1CCCN(CCOc2ccc(C(=O)c3c(-c4ccc(O)cc4)sc4cc(O)ccc34)cc2)C1>>CC1CCCN(CCOc2ccc(C(O)c3c(-c4ccc(O)cc4)sc4cc(O)ccc34)cc2)C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060019940A1,CC1Cc2ccc(Br)cc2N(c2ccccc2)CCO1.Cc1noc(C)c1B(O)O>>Cc1noc(C)c1-c1ccc2c(c1)N(c1ccccc1)CCOC(C)C2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US05807899,ClCCCCCBr.O=C(CCCO)c1ccccc1-c1ccccc1>>CCC(C(=O)c1ccc(OCCCCCCl)cc1)c1ccccc1,,CCOC(C)=O,O,CC#N,O=C([O-])[O-].[K+].[K+],test
US20030119054A1,CCCCCc1cc(O)ccc1O>>CCCCCC1=CC(=O)C=CC1=O,,CO,,CCCCCC,CCOC(C)=O,test
US20060287286A1,CC1(C)OCc2cc(C(=O)CN=[N+]=[N-])ccc2O1>>CC1(C)OCc2cc([C@@H](O)CN=[N+]=[N-])ccc2O1,,C1CCOC1,Cc1ccccc1,B,Cl,test
US20060111353A1,NCCc1ccccn1.O=S(=O)(Cl)c1ccc(Br)cc1>>O=S(=O)(NCCc1ccccn1)c1ccc(Br)cc1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US06376426B1,CI.O=c1cc(C(F)(F)F)[nH]c(=O)n1-n1ccc2c(Cl)cccc21>>Cn1c(C(F)(F)F)cc(=O)n(-n2ccc3c(Cl)cccc32)c1=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080132551A1,CCCC[Sn](CCCC)(CCCC)c1ccco1.Nc1ccccc1I>>Nc1ccccc1-c1ccco1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20150072980A1,COc1cc2c(cc1N1CCOCC1)C/C(=C\c1cc(Br)cc(OC(F)(F)F)c1)C2=O>>COc1cc2c(cc1N1CCOCC1)CC(Cc1cccc(OC(F)(F)F)c1)C2=O,[Pd],CO,,,,test
US20140161729A1,COC(=O)c1cc(C)c(O)c(C=O)c1.O=C(Cl)c1ccccc1>>COC(=O)c1cc(C)c(OC(=O)c2ccccc2)c(C=O)c1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20110034507A1,CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CCl.COC(=O)c1cccc(C2Cc3ccc(O)cc3C2)c1>>COC(=O)c1cccc(C2Cc3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3C2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150291563A1,CC(C)(C)OC(=O)N1CC=C(c2cccc(C3CC(C(F)(F)C(F)(F)F)=NN3c3ccccc3Cl)c2)CC1.O=C(O)C(F)(F)F>>FC(F)(F)C(F)(F)C1=NN(c2ccccc2Cl)C(c2cccc(C3=CCNCC3)c2)C1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20090137561A1,COC(=O)c1cc(CO[Si](C)(C)C(C)(C)C)ccc1-c1cc(OC)ccc1F>>COc1ccc(F)c(-c2ccc(CO[Si](C)(C)C(C)(C)C)cc2CO)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04049693,C=CC#N.Cl.O=S(=O)(Cl)c1ccc(OC(F)(F)C(Cl)Cl)cc1>>N#CC(Cl)CS(=O)(=O)c1ccc(OC(F)(F)C(Cl)Cl)cc1,,CC#N,,CCN(CC)CC,,test
US20140206663A1,CC1C(=O)NN=C2COc3ccc(C4=CCN(C(=O)OC(C)(C)C)CC4)cc3N21>>CC1C(=O)NN=C2COc3ccc(C4CCN(C(=O)OC(C)(C)C)CC4)cc3N21,[Pd],CO,,,,test
US20120277212A1,C=C[Sn](CCCC)(CCCC)CCCC.CC(C)(C)ON=c1cc(-c2cc3ccccc3cn2)oc2ccc(Br)cc12>>C=Cc1ccc2oc(-c3cc4ccccc4cn3)cc(=NOC(C)(C)C)c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20080227834A1,Cc1ccc(C#N)c(C(F)(F)F)c1.O=C1CCC(=O)N1Br>>N#Cc1ccc(CBr)cc1C(F)(F)F,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20020193402A1,O=O.O=S(=O)(c1ccccc1)C1CC2(c3ccccc3)C(OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)CCC1N2Cc1ccccc1>>O=C1C[C@@]2(c3ccccc3)[C@H](OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC[C@H]1N2Cc1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US20140349993A1,Cc1cc([N+](=O)[O-])cc(Br)[n+]1[O-]>>Cc1cc(N)cc(Br)n1,[Fe],CC(=O)O,,,,test
US04381393,CNC.COc1ccc(C(=O)c2[nH]c(=O)[nH]c2CBr)cc1>>COc1ccc(C(=O)c2[nH]c(=O)[nH]c2CN(C)C)cc1,,CCO,,,,test
US20150232481A1,CCN(C(C)C)C(C)C.CCOC(=O)c1cc2nc(C)c([C@H](OC(C)(C)C)C(=O)OCC)c(Cl)n2n1.CCOC(C)=O.CCOCC.CN(C)C=O>>C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(C(=O)OCC)nn23)CC1,,CCOCC,,,,test
US20150133432A1,CNOC.Cc1nn(C2CCCCO2)c2nc(-c3ccc(OCc4ccccc4)cc3F)cc(C(=O)O)c12>>CON(C)C(=O)c1cc(-c2ccc(OCc3ccccc3)cc2F)nc2c1c(C)nn2C1CCCCO1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20020010334A1,CCOC(=O)C=C(N)C(F)(F)F.CCOC(=O)Nc1ccc(OC)cc1.CN(C)C=O>>COc1ccc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06831080B2,NO.O=C(c1cccc([N+](=O)[O-])c1)C(F)(F)F>>O=[N+]([O-])c1cccc(C(=NO)C(F)(F)F)c1,,CCO,,CCN(CC)CC,Cl,test
US20060188663A1,CCCCCc1ccc(O)cc1.Cc1cc(C(=O)O)ccc1[N+](=O)[O-]>>CCCCCc1ccc(OC(=O)c2ccc([N+](=O)[O-])c(C)c2)cc1,CN(C)c1ccncc1,C1CCOC1,CCN(CC)CC,,,test
US20060211603A1,CCOC(=O)CC(=O)CCl.NC(=O)C1CCCCC1>>CCOC(=O)Cc1coc(C2CCCCC2)n1,,C1COCCO1,Cc1ccccc1,,,test
US20020052498A1,CCCCCCCCCCCCCCCCCCOc1ccccc1CCC(=O)NCCCN(C)C.Cl>>CCCCCCCCCCCCCCCCCCOc1ccccc1CCC(=O)NCCCN(C)C.Cl,,CCOC(C)=O,,,,test
US20050009804A1,COC(=O)c1sc(-c2ccccc2)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)[C@@H]1CC[C@@H](O)CC1>>C[C@H]1CC[C@H](C(=O)N(c2cc(-c3ccccc3)sc2C(=O)O)[C@@H]2CC[C@@H](O)CC2)CC1,,C1COCCO1,,O,[Li+].[OH-],test
US20110152297A1,COC(=O)[C@@H]1C[C@H](O)CCN1C(=O)OC(C)(C)C.COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1O>>COC(=O)[C@@H]1C[C@@H](Oc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC)CCN1C(=O)OC(C)(C)C,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US05219876,CCC(C#N)(CBr)c1ccc(Br)cc1.c1nc[nH]n1>>CCC(C#N)(Cn1cncn1)c1ccc(Br)cc1,,CS(C)=O,,O,[Na+].[OH-],test
US04288624,CC(=O)C(=CN(C)C)c1cccc(C(F)(F)F)c1.FC(F)(F)SCl>>CN(C)C=C(C(=O)CSC(F)(F)F)c1cccc(C(F)(F)F)c1,,C1CCOC1,CCCCCC,CC(C)NC(C)C,[Li]CCCC,test
US04399131,CCCON=C(C(=O)CBr)C(=O)OCC.NC(N)=S>>CCCON=C(C(=O)OCC)c1csc(N)n1,,CCO,,O,,test
US20050267180A1,CCO[C@H](C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1)[C@H](O)c1ccc(OCc2ccccc2)cc1C>>CCO[C@@H](Cc1ccc(OCc2ccccc2)cc1C)C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20060069110A1,CN(c1ccnc(F)n1)c1ccnc(-c2ccccc2)n1.C[C@H](NC(=O)OC(C)(C)C)c1cccc(CCN)c1>>C[C@H](NC(=O)OC(C)(C)C)c1cccc(CCNc2nccc(N(C)c3ccnc(-c4ccccc4)n3)n2)c1,,C1COCCO1,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],,test
US20090054304A1,CC(C)n1ncc2cc(C=O)c(Cl)nc21.OB(O)c1ccsc1>>CC(C)n1ncc2cc(C=O)c(-c3ccsc3)nc21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20080242661A1,CCCc1nn(C)c2c(Cl)nc(Cl)nc12.[OH-]>>CCCc1nn(C)c2c(=O)[nH]c(Cl)nc12,,C1COCCO1,O,Cl,,test
US20060241127A1,Clc1ccnc2[nH]ccc12.Nc1ccc(O)cc1F>>Nc1ccc(Oc2ccnc3[nH]ccc23)cc1F,,O,,[K+].[OH-],,test
US20090209553A1,CCOC(=O)C1(Br)CCC1.Nc1ccc2[nH]ncc2c1>>CCOC(=O)C1(Nc2ccc3[nH]ncc3c2)CCC1,,CCO,ClCCl,CCN(CC)CC,,test
US20140249104A1,CC(C)(C)[S@@](=O)N[C@@](CF)(C[C@H](O)C(F)(F)F)c1cc(Br)cnc1F>>N[C@@](CF)(C[C@H](O)C(F)(F)F)c1cc(Br)cnc1F,,CO,ClCCl,C1COCCO1,Cl,test
US20130045942A1,C[C@H](N)c1ccc([N+](=O)[O-])cc1.OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O>>C[C@H](Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)c1ccc([N+](=O)[O-])cc1,,CCCO,,,,test
US20100105642A1,Cn1nnc(-c2cccc(CCOCCC(=O)OC(C)(C)C)c2)n1>>Cn1nnc(-c2cccc(CCOCCC(=O)O)c2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110212918A1,COC(=O)c1cc(NC(=O)C(F)(F)F)cnc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2>>Nc1cnc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(C(=O)O)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20120101080A1,CCCCCC(=O)Cl.c1ccc(C2CCNC2)cc1>>CCCCCC(=O)N1CCC(c2ccccc2)C1,,ClCCl,,CCN(CC)CC,,test
US20100152450A1,COC(=O)CCc1cc(-c2cncc(OC[C@@H]3CCN3C(=O)OC(C)(C)C)c2)on1.Cl>>COC(=O)CCc1cc(-c2cncc(OC[C@@H]3CCN3)c2)on1.Cl,,CCOCC,CO,,,test
US20150368265A1,CNC(=O)c1c(C(=O)NNC(C)=O)oc2cc(N(C)S(C)(=O)=O)c(Br)cc12>>CNC(=O)c1c(-c2nnc(C)o2)oc2cc(N(C)S(C)(=O)=O)c(Br)cc12,,ClCCl,,CCN(CC)CC,,test
US04028393,CC(C)O.N#CCl.Oc1cccc(O)c1>>N#C[O-].Oc1cccc(O)c1,,CC(C)O,,CCN(CC)CC,,test
US04454134,CC(=NO)SC(C)C(N)=O.CN=C=O>>CNC(=O)ON=C(C)SC(C)C(N)=O,CCN(CC)CC,CC(C)=O,,,,test
US20050215645A1,CC(=O)Oc1cccc2cc(S(=O)(=O)NCc3ccccc3)ccc12>>O=S(=O)(NCc1ccccc1)c1ccc2c(O)cccc2c1,,CCO,,Cl,[Na+].[OH-],test
US20090163586A1,NS(=O)(=O)c1sccc1[N+](=O)[O-]>>Nc1ccsc1S(N)(=O)=O,,CCOC(C)=O,,I,,test
US20060167248A1,COc1cccc(C)c1N.O=C1CCC(=O)N1Br>>COc1cc(Br)cc(C)c1N,,CC#N,,,,test
US20080287475A1,CC(C)Oc1cc(Nc2nc(Cl)ncc2Br)n[nH]1.C[C@H](N)c1ncc(F)cn1>>CC(C)Oc1cc(Nc2nc(N[C@@H](C)c3ncc(F)cn3)ncc2Br)n[nH]1,,CCCCO,,CCN(C(C)C)C(C)C,Cl,test
US20090018132A1,CC(C)(C)OC(=O)N1CCC(COCc2cc(C(F)(F)F)cc3cc[nH]c23)(c2ccccc2)CC1>>CN1CCC(COCc2cc(C(F)(F)F)cc3cc[nH]c23)(c2ccccc2)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070197512A1,CCOC(=O)/C=C/C(=O)Cl.Cc1cccc2c1OC(C(C)C)CN2>>CCOC(=O)/C=C/C(=O)N1CC(C(C)C)Oc2c(C)cccc21,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20070213311A1,CC1(C)CC2CC(C)(CN2C(=O)C(=O)c2ccc(Br)cc2F)C1.C[Mg]Br>>CC1(C)CC2CC(C)(CN2C(=O)C(C)(O)c2ccc(Br)cc2F)C1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US04226867,CN(C)C1CCC(=O)CC1.Nc1cc(Cl)c(S(N)(=O)=O)cc1S(N)(=O)=O>>CN(C)C1CCC2(CC1)Nc1cc(Cl)c(S(N)(=O)=O)cc1S(=O)(=O)N2,,Cl,,,,test
US04684220,Brc1ccccc1.CCCCC(=O)Cl>>CCCCC(=O)c1ccc(Br)cc1,,S=C=S,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20110077273A1,BrCC1CCCCC1.COc1cc(Cl)ccc1-c1nc2cc(F)c(F)cc2[nH]1>>COc1cc(Cl)ccc1-c1nc2cc(F)c(F)cc2n1CC1CCCCC1,,CN(C)C=O,,[H-].[Na+],,test
US20110230483A1,CCCC[Sn](CCCC)(CCCC)c1ncco1.COC(=O)c1nc(Br)c(C(F)(F)F)cc1N>>COC(=O)c1nc(-c2ncco2)c(C(F)(F)F)cc1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20090111809A1,CC(C)[Si](OS(=O)(=O)C(F)(F)F)(C(C)C)C(C)C.N#Cc1ccc(Oc2cc(Cl)c(C[C@@H]3CCN(N4CCC(O)CC4)C3=O)c(Cl)c2)cc1>>CC(C)[Si](OC1CCN(N2CC[C@@H](Cc3c(Cl)cc(Oc4ccc(C#N)cc4)cc3Cl)C2=O)CC1)(C(C)C)C(C)C,,ClCCl,,c1ccncc1,,test
US20090203582A1,CC(C)(C)OC(=O)NC[C@H](NC(=O)OCc1ccccc1)C(=O)O.CC(O)[Si](C)(C)C>>CC(C)(C)OC(=O)NC[C@H](NC(=O)OCc1ccccc1)C(=O)OCC[Si](C)(C)C,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20050256313A1,CC(O)C(=O)O.CCCCC(C=O)CC>>CCCCC(CC)C1OCC(=O)O1,,O,,ClC(Cl)Cl,,test
US20140031338A1,COC(=O)C(OC(C)(C)C)c1cc([N+](=O)[O-])c(F)cc1Cl.Oc1ccccc1>>COC(=O)C(OC(C)(C)C)c1cc([N+](=O)[O-])c(Oc2ccccc2)cc1Cl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130059863A1,C=CCI.COC(=O)C1CCCCC1>>C=CCC1(C(=O)OC)CCCCC1,,C1CCOC1,CN(C)P(=O)(N(C)C)N(C)C,CC(C)NC(C)C,[Li]CCCC,test
US20090209475A1,C=CCO[C@H]1O[C@H](COS(=O)(=O)c2ccc(C)cc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1.OO>>Cc1ccc(S(=O)(=O)OC[C@H]2O[C@H](OCCCO)[C@H](OCc3ccccc3)[C@@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)cc1,,C1CCOC1,O,B1C2CCCC1CCC2,[Na+].[OH-],test
US20090286984A1,Brc1ccc(C2OCCCO2)cn1>>Brc1ccc(C2OCCO2)cn1,,OCCO,,,,test
US20150198876A1,C1=CCC=C1.C=C(C(=O)O)C(F)(F)F>>O=C(O)C1(C(F)(F)F)CC2C=CC1C2,,c1ccccc1,,CCCCCC,,test
US20120264737A1,CCC(=O)Cl.COC(=O)c1cc(C(C)=O)c(C2CCC2)cc1C>>CCC(=O)CC(=O)c1cc(C(=O)OC)c(C)cc1C1CCC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20110021494A1,CCOC(=O)c1cc2c(n1C)CCN(C(=O)OC(C)(C)C)C2>>Cn1c(C(=O)O)cc2c1CCN(C(=O)OC(C)(C)C)C2,,CCO,,[Na+].[OH-],,test
US20160102107A1,CNc1cc(Br)cc(OC)c1[N+](=O)[O-]>>CNc1cc(Br)cc(OC)c1N,[Ni],C1CCOC1,CO,,,test
US20110086841A1,CCN(CC)S(F)(F)F.C[C@H]1COCCN1c1nc(Cl)nc2c1nc(C1(O)COC1)n2C>>C[C@H]1COCCN1c1nc(Cl)nc2c1nc(C1(F)COC1)n2C,,ClCCl,,,,test
US20080200471A1,O=C(OCc1ccccc1)N1CCN2CCCCC2C1>>C1CCN2CCNCC2C1,[Pd],CO,ClCCl,[H][H],,test
US20110224155A1,CC(=O)Cl.N#Cc1c(OCCCCCCCCO)cccc1[N+](=O)[O-]>>CC(=O)OCCCCCCCCOc1cccc([N+](=O)[O-])c1C#N,,ClCCl,,c1ccncc1,,test
US20050107377A1,Fc1ccc2c(-c3ccc(OC[C@@H]4CO4)cc3)noc2c1.c1ccc(C2CCNCC2)cc1>>O[C@H](COc1ccc(-c2noc3cc(F)ccc23)cc1)CN1CCC(c2ccccc2)CC1,,CCO,CN(C)C=O,,,test
US20100261755A1,CCOC(=O)C1CCN(C(=O)OCc2ccccc2)C(c2nnnn2C)C1>>Cn1nnnc1C1CC(C(=O)O)CCN1C(=O)OCc1ccccc1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20150366252A1,N.N#Cc1c(F)cccc1OCC1(C(=O)NC2CCCCC2)CCCNC1=O>>N#Cc1c(N)cccc1OCC1(C(=O)NC2CCCCC2)CCCNC1=O,,CC(C)O,,,,test
US20140256756A1,CC(C)c1nsc(N2CCC(N)CC2)n1.O=C(Cl)C(Br)CCBr>>CC(C)c1nsc(N2CCC(NC(=O)C(Br)CCBr)CC2)n1,,C1CCOC1,,CCN(CC)CC,Cl,test
US04857558,Br[Mg]C1CCCCC1.CC(C)(C)c1cc(SCCC=O)cc(C(C)(C)C)c1O>>CC(C)(C)c1cc(SCCC(O)C2CCCCC2)cc(C(C)(C)C)c1O,,C1CCOC1,,,,test
US20070265301A1,BrCc1ccccc1.CC(C)(C)OC(=O)N1c2ccccc2CC1CO>>CC(C)(C)OC(=O)N1c2ccccc2CC1COCc1ccccc1,,C1CCOC1,CCOC(C)=O,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US05142048,C1COCCN1.CN(CCC(=O)O)C(=O)OC(C)(C)C>>CN(CCC(=O)N1CCOCC1)C(=O)OC(C)(C)C,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20040254205A1,C=CCc1c(O)c(OC)cc2ncnc(Nc3ccc(F)c(Cl)c3)c12.CI>>C=CCc1c(OC)c(OC)cc2ncnc(Nc3ccc(F)c(Cl)c3)c12,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040092507A1,CC(C)(C)OC(=O)N1CCN(c2ccccc2O)CC1.Cn1ccnc1CO>>Cn1ccnc1COc1ccccc1N1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140142083A1,CCN(c1cc(F)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1C[C@@H](C)N(Cc2ccccc2)[C@H](C)C1>>CCN(c1cc(F)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1C[C@@H](C)N[C@H](C)C1,[Pd],CO,,,,test
US20150175619A1,CCOC(=O)C1C2CC(O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)CC21>>CC(C)(C)[Si](OC1CC2C(C1)C2C(=O)O)(c1ccccc1)c1ccccc1,,CCO,O,[Na+].[OH-],,test
US20070093484A1,CCOC(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1Cn1ncnn1.NC1CCC(F)(F)CC1>>O=C(NC1CCC(F)(F)CC1)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1Cn1ncnn1,,ClCCl,,C[Al](C)C,,test
US04432972,CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)OCc1ccccc1.O=P(Cl)(Cl)c1ccccc1.OCc1ccccc1>>CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NP(=O)(OCc1ccccc1)c1ccccc1)C(=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
US20070185184A1,Clc1ccc2cc[nH]c2c1.O=[N+]([O-])c1ccc(F)c(Cl)c1>>O=[N+]([O-])c1ccc(-n2ccc3ccc(Cl)cc32)c(Cl)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20050171164A1,C=O.CC(C)O.CCOC(C)=O.N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1SC(F)(F)F>>CCCOCNc1c(SC(F)(F)F)c(C#N)nn1-c1c(Cl)cc(C(F)(F)F)cc1Cl,,CCOC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20140243532A1,CC(C)(C)OC(=O)[C@@H](CCCO)C[C@H](NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1C(F)(F)F>>CC(C)(C)OC(=O)[C@@H](CCCOS(=O)(=O)c1ccc([N+](=O)[O-])c(C(F)(F)F)c1)C[C@H](NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,O,test
US20080269193A1,CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3cc(F)c(C#N)c(N[C@H]4CCC[C@@H]4O)c3)c2C1.OO>>CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3cc(F)c(C(N)=O)c(N[C@H]4CCC[C@@H]4O)c3)c2C1,,CCO,CS(C)=O,[Na+].[OH-],,test
US04881967,C=CCOc1cc([N+](=O)[O-])ccc1Cl>>C=CCOc1cc(N)ccc1Cl,,CCO,,[Na+].[OH-],,test
US03969463,COc1ccc2nc(C)ccc2c1>>COc1ccc2c(c1)CCC(C)N2,[Rh],,,,,test
US20140088101A1,CCOC(=O)C(C=CN(C)C)=C(C(=O)OC)C(=O)OC.COc1ccc(CN)c(OC)c1>>CCOC(=O)c1ccn(Cc2ccc(OC)cc2OC)c(=O)c1C(=O)OC,,CCO,,,,test
US20040192728A1,COC(=O)c1ccc2c(c1)CCN2C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCc2cc(C(=O)O)ccc21,,CO,,[Na+].[OH-],,test
US20120171245A1,CCN.O=C(O)[C@]1(O)CCC[C@H](Nc2nc(-c3c[nH]c4ncc(Cl)cc34)ncc2F)C1>>CCNC(=O)[C@]1(O)CCC[C@H](Nc2nc(-c3c[nH]c4ncc(Cl)cc34)ncc2F)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100261725A1,CC(C)(C)OC(=O)c1c(-c2ccc(Cl)cc2)csc1NC(=O)c1nc2cc(Br)ccc2o1>>O=C(Nc1scc(-c2ccc(Cl)cc2)c1C(=O)O)c1nc2cc(Br)ccc2o1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090170894A1,Cl.O=C(N1CCCc2ccccc21)N1C2CCC1CC(c1cccnc1)C2>>Cl.O=C(N1CCCc2ccccc21)N1C2CCC1CC(c1cccnc1)C2,,C1COCCO1,ClCCl,,,test
US20100120801A1,BrP(Br)Br.OC[C@H]1CCCCN1Cc1ccccc1>>BrC[C@H]1CCCCN1Cc1ccccc1,,c1ccccc1,,Cl,,test
US05238949,Cc1cc(C)c(C=O)c(C)c1.NCc1ccc(Cl)nc1>>Cc1cc(C)c(C=NCc2ccc(Cl)nc2)c(C)c1,,O,,Cc1ccccc1,,test
US20090318445A1,O=C(OCc1ccccc1)N1CCCC1c1nc2ncccc2o1>>c1cnc2nc(C3CCCN3)oc2c1,[Pd],CCOC(C)=O,CO,,,test
US20100063038A1,CCCCOC(=O)c1cc(-c2ccc(NC(=O)Nc3cccc(C(F)(F)F)n3)cc2)c2c(N)ncnn12>>Nc1ncnn2c(C(=O)O)cc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)n4)cc3)c12,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US06258976B1,N.N#CCCCCCN=C=S>>N#CCCCCCNC(N)=S,,C1COCCO1,,,,test
US20160106754A1,CC1(C)CC(=O)CC(=O)N1.COc1cc(SSc2cc(OC)c(Cl)cc2N)c(N)cc1Cl>>COc1cc2c(cc1Cl)NC1=C(S2)C(=O)NC(C)(C)C1,CCN(CC)CC,CCO,,,,test
US20110039889A1,N=C(NO)c1cccc2cnccc12.O=C(O)c1ccc(OCC(F)(F)F)nc1>>FC(F)(F)COc1ccc(-c2nc(-c3cccc4cnccc34)no2)cn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160152621A1,CC(=O)Cl.COC(=O)c1ccc(N)cc1OC>>COC(=O)c1ccc(NC(C)=O)cc1OC,,ClCCl,,CCN(CC)CC,,test
US20040132727A1,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.COc1ccc(C(C)O)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc(C(C)OC(=O)Nc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2)cc1,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20150191461A1,NC(N)=O.O=C(O)CC(Cn1cc(I)cn1)C(=O)O>>O=C1CC(Cn2cc(I)cn2)C(=O)N1,,O,,,,test
US20100121052A1,NC(N)=O.Nc1ccc(Br)cc1C=O>>Oc1ncc2cc(Br)ccc2n1,,O,,,,test
US20140309208A1,CN1Cc2cccc(O)c2C1=O.O=[N+]([O-])O>>CN1Cc2ccc([N+](=O)[O-])c(O)c2C1=O,,O=S(=O)(O)O,,O,[Cl-].[Na+],test
US20100035918A1,CC(C(O)c1ccc2ncnn2c1)[N+](=O)[O-].CC(C)(C)[Si](C)(C)Cl>>CC(C(O[Si](C)(C)C(C)(C)C)c1ccc2ncnn2c1)[N+](=O)[O-],,CN(C)C=O,,c1c[nH]cn1,,test
US20120295885A1,CC(C)(C)c1cc(F)c2c(=O)[nH]ncc2c1.N#Cc1cn(-c2cccc(I)c2C=O)nc1Nc1ccc(C(=O)N2CCOCC2)cc1>>CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C#N)c(Nc5ccc(C(=O)N6CCOCC6)cc5)n4)c3C=O)ncc2c1,,CS(C)=O,,O=C([O-])O.[Na+],,test
US20020068729A1,Cc1ncsc1C.O=C(CBr)c1ccc(O)cc1>>Cc1sc[n+](CC(=O)c2ccc(O)cc2)c1C.[Br-],,CC#N,,COC(C)(C)C,,test
US20140287916A1,Cc1cnc(CO)nc1.O=C1CCC(=O)N1Br>>Cc1cnc(CBr)nc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070010542A1,Cc1c(OCC2(C)OCC3(CO2)OCCO3)ccnc1CSc1nc2ccccc2[nH]1.O=C(OO)c1cccc(Cl)c1>>Cc1c(OCC2(C)OCC3(CO2)OCCO3)ccnc1CS(=O)c1nc2ccccc2[nH]1,,CO,,Cc1ccccc1,,test
US20070161654A1,BrBr.CC(=O)c1conc1-c1ccccc1>>O=C(CBr)c1conc1-c1ccccc1,,CC(=O)O,ClC(Cl)Cl,,,test
US20060009439A1,O=C(OCc1ccccc1)N1CCNCC1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>O=C(OCc1ccccc1)N1CCN(CC(F)(F)F)CC1,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20040147525A1,Cc1ccc(S(=O)(=O)CCC(=O)CC2CCCN2C(=O)OC(C)(C)C)cc1>>O=C1CCN2CCCC2C1,,CO,,C1COCCO1,Cl,test
US05387685,COc1cc2c(cc1OC)CNC2.COc1ccc(C(CCCCC(C)Br)Sc2ccc(C)cc2)cc1OC>>COc1ccc(C(CCCCCCN2Cc3cc(OC)c(OC)cc3C2)Sc2ccc(C)cc2)cc1OC,,CC#N,,CCN(C(C)C)C(C)C,,test
US20080300232A1,NC1CCN(Cc2ccccc2)CC1.O=C(Cl)CCl>>O=C(CCl)NC1CCN(Cc2ccccc2)CC1,,ClCCl,,,,test
US20030055055A1,COS(=O)(=O)OC.O=[N+]([O-])c1cccc(-c2ccncc2)c1>>COS(=O)(=O)[O-].C[n+]1ccc(-c2cccc([N+](=O)[O-])c2)cc1,,CCOCC,,,,test
US20100261708A1,CC(C)(C)OC(=O)N1CCCNCC1.O=C(O)C1CCOCC1>>CC(C)(C)OC(=O)N1CCCN(C(=O)C2CCOCC2)CC1,,C1CCOC1,ClCCl,CCN(CC)CC,O=S(Cl)Cl,test
US20160102105A1,CC[Si](CC)(CC)c1cc(Br)nc([C@]2(C)C[S@@](=O)(=NCCCO)C(C)(C)C(NC(=O)OC(C)(C)C)=N2)c1F.Cc1ccc(S(=O)(=O)Cl)cc1>>CC[Si](CC)(CC)c1cc(Br)nc([C@]2(C)C[S@@](=O)(=NCCCOS(=O)(=O)c3ccc(C)cc3)C(C)(C)C(NC(=O)OC(C)(C)C)=N2)c1F,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,[Cl-].[NH4+],test
US20030191113A1,[N-]=[N+]=Nc1ccnc(C(=O)Nc2ccc(Oc3ccccc3)cc2)c1O>>Nc1ccnc(C(=O)Nc2ccc(Oc3ccccc3)cc2)c1O,[Pd],CCO,CCOC(C)=O,,,test
US20160145245A1,COCCOCCOCCO[C@H]1CCNC1.O=C(N[C@H](C(=O)O)c1ccccc1)OCc1ccccc1>>COCCOCCOCCO[C@H]1CCN(C(=O)[C@@H](NC(=O)OCc2ccccc2)c2ccccc2)C1,,CC#N,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US04562294,C=CC=C.Cc1cc(CN(C)C)cc(C(C)(C)C)c1O>>CC1=CC2(C=C(C(C)(C)C)C1=O)CC=CCC2,,Cc1ccccc1,,,,test
US20040152751A1,CCCCC(C(=O)OCC)C(=O)OCC.COc1ccc(NNc2ccccc2)cc1>>CCCCC1C(=O)N(c2ccccc2)N(c2ccc(OC)cc2)C1=O,,CCO,,[Na],,test
US20100004239A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCNCCN1CCc2[nH]cc(C)c2C1=O>>CCN(CCN1CCc2[nH]cc(C)c2C1=O)C(=O)OC(C)(C)C,,CC(C)O,O,O=C([O-])[O-].[K+].[K+],,test
US20120295884A1,CC(=O)c1c[nH]c2ccc(OC(F)(F)F)cc12.CC(C)(C)OC(=O)CBr>>CC(=O)c1cn(CC(=O)OC(C)(C)C)c2ccc(OC(F)(F)F)cc12,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100056532A1,CCOC(=O)c1c(C2CCCN(C(=O)OCc3ccccc3)C2)csc1N.O=C(Cl)c1cccc(F)c1>>CCOC(=O)c1c(C2CCCN(C(=O)OCc3ccccc3)C2)csc1NC(=O)c1cccc(F)c1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20060229309A1,CCCN(CCC)C(=O)c1cccc(C(=O)OC)c1>>CCCN(CCC)C(=O)c1cccc(C(=O)O)c1,,C1CCOC1,O,[Li+].[OH-],,test
US05412144,COc1ccc(CCCCCCC(=O)O)cc1>>O=C(O)CCCCCCc1ccc(O)cc1,,O,,Br,CC(=O)O,test
US20160068559A1,CC(C)(C)c1ccc(NC(=O)NCCC(=O)O)cc1.CCNC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21>>CCN(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21)C(=O)CCNC(=O)Nc1ccc(C(C)(C)C)cc1,,CN(C)C=O,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US04470973,CC(C)(C)OC(=O)C1Cc2ccccc2CN1C(=O)CBr.CNCC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1>>CN(CC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1)CC(=O)N1Cc2ccccc2C[C@H]1C(=O)OC(C)(C)C,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US06136823,CN.Cc1c(F)c(F)c(O)c2c(=O)c(C(=O)O)cn(-c3cc(N)c(F)cc3F)c12>>CNc1c(F)c(O)c2c(=O)c(C(=O)O)cn(-c3cc(N)c(F)cc3F)c2c1C,CC(=O)O,CCO,,c1ccncc1,,test
US20110281843A1,N#Cc1cc(Oc2cc(F)cc(F)c2)ccc1[N+](=O)[O-]>>N#Cc1cc(Oc2cc(F)cc(F)c2)ccc1N,[Pd],C1COCCO1,,,,test
US05017724,BrBr.COc1c(C)cc(C)cc1C(=O)C1CCCCC1>>COc1c(C)cc(C)cc1C(=O)C1(Br)CCCCC1,,CC(=O)O,,Br,,test
US20070232591A1,C#CC(N)=O.C1=C(N2CCCC2)CCN(Cc2ccccc2)C1>>O=c1ccc2c([nH]1)CCN(Cc1ccccc1)C2,,Cc1ccccc1,,,,test
US20100152450A1,Cl.O[C@@H](Cc1ccccc1)Cc1cccc(-c2cncc(OC[C@@H]3CCN3)c2)c1>>Cl.O[C@@H](Cc1ccccc1)Cc1cccc(-c2cncc(OC[C@@H]3CCN3)c2)c1,,CO,,,,test
US05519133,COC(=O)Cn1c(=O)[nH]c(=O)n(-c2cc(F)ccc2[N+](=O)[O-])c1=O.Oc1ccc(Cl)cc1Cl>>COC(=O)Cn1c(=O)[nH]c(=O)n(-c2cc(Oc3ccc(Cl)cc3Cl)ccc2[N+](=O)[O-])c1=O,,CCOC(C)=O,CN(C)C=O,Cl,O=C([O-])[O-].[K+].[K+],test
US20060122399A1,CC(=O)c1ccc(O)cc1O.CI>>COc1ccc(C(C)=O)c(O)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150376169A1,CCOC(CN)OCC.CN(c1ccccc1)c1cccc(CCO)c1>>CN(c1ccccc1)c1ccc2c(c1)CCOC2CN,,C1COCCO1,Cl,,,test
US04963553,CC1=C(c2cccc(C(F)(F)F)c2)n2ncc(C#N)c2N(C(=O)CCl)C1.c1ccc(N2CCNCC2)nc1>>CC1=C(c2cccc(C(F)(F)F)c2)n2ncc(C#N)c2N(C(=O)CN2CCN(c3ccccn3)CC2)C1,,CC(C)=O,,,,test
US20100056510A1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.NCC1(CN)COC1>>NCC1(CNC(c2ccccc2)(c2ccccc2)c2ccccc2)COC1,,O,,ClCCl,O=C([O-])O.[Na+],test
US06703468B1,C=C(C)C(N)=O.N=C(N)NCCC[C@H](N)C(=O)O>>C=C(C)C(N)=O.N=C(N)NCCC[C@H](N)C(=O)O,,O,,Cl,,test
US07473698B2,CC(C)(C)OC(=O)CCCN.COC(=O)C1=C(C)N=C(OC)N(C(=O)Oc2ccc([N+](=O)[O-])cc2)C1c1ccc(F)cc1>>COC(=O)C1=C(C)N=C(OC)N(C(=O)NCCCC(=O)OC(C)(C)C)C1c1ccc(F)cc1,,CO,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20130029954A1,C=C(C)[C@@H]1CC[C@]2(CN(CCN(C)C)C(=O)CCC(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC(C)(C)C)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(CN(CCN(C)C)C(=O)CCC(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060100283A1,CCCCS(=O)c1cc(OC[C@@H](O)CN[C@@H]2CC[C@@H](c3ccc(OC(C)(C)C(=O)OCC)cc3)CC2)ccc1OCc1ccccc1>>CCCCS(=O)c1cc(OC[C@@H](O)CN[C@@H]2CC[C@@H](c3ccc(OC(C)(C)C(=O)OCC)cc3)CC2)ccc1O,,O=C(O)C(F)(F)F,,,,test
US20140094459A1,O=[N+]([O-])c1ccc(F)cc1.Oc1c(F)cccc1F>>O=[N+]([O-])c1ccc(Oc2c(F)cccc2F)cc1,,CN(C)C=O,O,[H-].[Na+],,test
US20130225552A1,CC(C)(C)OC(=O)N[C@H]1C[C@H](O)C1.Cn1c(Cl)nc2ccccc21>>Cn1c(O[C@@H]2C[C@@H](NC(=O)OC(C)(C)C)C2)nc2ccccc21,,CN(C)C=O,O,[H-].[Na+],,test
US20120252792A1,Nc1ccc(Cl)cc1.O.O=C(O)CNCc1cc(C(F)(F)F)cc(C(F)(F)F)c1.On1nnc2ccccc21>>O=C(CONC(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)Nc1ccc(Cl)cc1,,CCOC(C)=O,,C1CCOC1,CCN(C(C)C)C(C)C,test
US20110060011A1,O=[N+]([O-])c1ccc(-c2nc(-c3ccncc3)c(C(F)(F)F)o2)cc1>>Nc1ccc(-c2nc(-c3ccncc3)c(C(F)(F)F)o2)cc1,[Pd],CCOC(C)=O,,[H][H],,test
US20140205537A1,CCc1nnc(C=O)n1S(=O)(=O)N(C)C.COc1ccc2c(c1)CC(=O)N2>>CCc1nnc(/C=C2\C(=O)Nc3ccc(OC)cc32)[nH]1,,CCO,,C1CCNCC1,,test
US05847122,CN(C)CCNc1ccccc1S.COc1ccc([C@@H]2O[C@H]2C(N)=O)cc1>>COc1ccc([C@H](Sc2ccccc2NCCN(C)C)[C@@H](O)C(N)=O)cc1,,CO,,Cc1ccccc1C,,test
US05124324,CI.CN1CCCCC1COC(=O)c1c[nH]c2ccccc12>>CN1CCCCC1COC(=O)c1cn(C)c2ccccc12,,C1CCOC1,,CN(C)C=O,[H-].[Na+],test
US20110183938A1,N#Cc1ncc2c(c1OC1CCNCC1)c1cc(Br)cnc1n2S(=O)(=O)c1ccccc1.O=S(=O)(OCC(F)F)C(F)(F)F>>N#Cc1ncc2c(c1OC1CCN(CC(F)F)CC1)c1cc(Br)cnc1n2S(=O)(=O)c1ccccc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20070032525A1,ClCc1ccc(Cl)c(Cl)c1.NCC1CCNCC1>>NCC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070149592A1,CO.Cl.NCCCCC(=O)O>>COC(=O)CCCCN.Cl,,CO,,CC(=O)Cl,,test
US06294573B1,C=CC(=O)OCC.CC(=O)N1CCNCC1>>CCOC(=O)CCN1CCN(C(C)=O)CC1,,C1CCOC1,,,,test
US04186135,CC(=O)OC(C)=O.Nc1ccc(C(=O)O)c2c1OCCO2>>CC(=O)Nc1ccc(C(=O)O)c2c1OCCO2,,CC(=O)O,,,,test
US20070078121A1,O=[N+]([O-])c1ccc2c(O)ncnc2c1>>Nc1ccc2c(O)ncnc2c1,[Pd],CN(C)C=O,,,,test
US20050107616A1,CC(C)(C)[C@@H](O)Cc1nnc(-c2ccc(C(F)(F)F)cc2)o1.CCCC[C@H](N=C=O)C(=O)OC>>CCCC[C@H](NC(=O)O[C@@H](Cc1nnc(-c2ccc(C(F)(F)F)cc2)o1)C(C)(C)C)C(=O)OC,,Cc1ccccc1,,,,test
US20160168156A1,CC(=O)NN.O=C(O)c1cnn2ccc(N3CCCC3c3cncc(F)c3)nc12>>CC(=O)NNC(=O)c1cnn2ccc(N3CCCC3c3cncc(F)c3)nc12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04083983,COc1ccnc(CSCCN)c1.CSC(=C[N+](=O)[O-])S(C)=O>>COc1ccnc(CSCCNC(=C[N+](=O)[O-])SC)c1.O,,CO,,,,test
US20100113465A1,Cc1noc(NC(=O)Oc2ccccc2)c1C.FC(F)(F)c1ccc(-c2nc(C3CC4(CCNCC4)C3)no2)cc1>>Cc1noc(NC(=O)N2CCC3(CC2)CC(c2noc(-c4ccc(C(F)(F)F)cc4)n2)C3)c1C,,CC#N,,CCN(C(C)C)C(C)C,,test
US20120196869A1,CC(C)(C)OC(=O)N1CCC2(CC1)NCCn1c(C(F)(F)F)ccc12.CN=C=O>>CNC(=O)N1CCn2c(C(F)(F)F)ccc2C12CCN(C(=O)OC(C)(C)C)CC2,,C1CCOC1,,CCN(CC)CC,,test
US20120184543A1,CC(C)(C)OC(=O)N1CCN(CC2CC2)CC1.ClC[C@H]1CO1>>C1CC1CN1CCN(C[C@@H]2CO2)CC1,,C1COCCO1,ClCCl,Cl,[Na+].[OH-],test
US05750767,OC1CCc2cc3ccccc3cc21>>C1=Cc2cc3ccccc3cc2C1,,O=S(=O)(O)O,,,,test
US20040242572A1,C1=CCNC1.CS(=O)(=O)OCc1ccc(CCNC(=O)c2ccc(-c3ccc(Cl)cc3)cc2)cc1>>O=C(NCCc1ccc(CN2CC=CC2)cc1)c1ccc(-c2ccc(Cl)cc2)cc1,,CCN(CC)CC,,,,test
US20140375943A1,O=C(OCCOCc1ccccc1)c1cc(C(=O)OCCOCc2ccccc2)cc(-c2ccc(OCc3ccccc3)cc2)c1>>O=C(OCCO)c1cc(C(=O)OCCO)cc(-c2ccc(O)cc2)c1,[Pd],C1CCOC1,,C,,test
US20120277208A1,COC(=O)c1cc(O)cc(Oc2ccc([N+](=O)[O-])cc2)c1.OCC1(COCc2ccccc2)CCC1>>COC(=O)c1cc(OCC2(COCc3ccccc3)CCC2)cc(Oc2ccc([N+](=O)[O-])cc2)c1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US05411980,CCCCc1nn(-c2cc(C(=O)OC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1>>CCCCc1nn(-c2cc(C(=O)OC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(N)(=O)=O)cc1,,CO,,ClCCl,,test
US20150087663A1,CC[C@H](N)c1nc2cccc(Cl)c2c(=O)n1C1CC1.Cn1nc(-c2c(N)ncnc2Cl)nc1C(N)=O>>CC[C@H](Nc1ncnc(N)c1-c1nc(C(N)=O)n(C)n1)c1nc2cccc(Cl)c2c(=O)n1C1CC1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20150164974A1,COC(=O)c1ccc(-c2ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)N3C[Si](C)(C)C[C@H]3C(=O)N[C@@H]3CCCc4ccccc43)cc2)cc1.Cl>>COC(=O)c1ccc(-c2ccc(C[C@H](N)C(=O)N3C[Si](C)(C)C[C@H]3C(=O)N[C@@H]3CCCc4ccccc43)cc2)cc1.Cl,,ClCCl,,,,test
US20100311730A1,CC(C)(C)OC(=O)N1CCC(CNc2cc(Cl)ncc2I)CC1.COC/C=C/B1OC(C)(C)C(C)(C)O1>>COC/C=C/c1cnc(Cl)cc1NCC1CCN(C(=O)OC(C)(C)C)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20100004238A1,O=C1NCc2c(Br)ccc(O)c21>>O=C1NCc2cccc(O)c21,[Pd],CO,,,,test
US20100034773A1,O=C(NS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)[C@@H]3[C@H]4CC[C@H](C4)[C@@H]3N(Cc3ccc(F)cc3)C1=O)N2)OCc1ccccc1>>NS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)[C@@H]3[C@H]4CC[C@H](C4)[C@@H]3N(Cc3ccc(F)cc3)C1=O)N2,,CO,,,,test
US20150166513A1,N#Cc1cc(F)c(C=NO)c(F)c1>>N#Cc1cc(F)c(CN)c(F)c1,[Zn],CC(=O)O,,N,,test
US20110021516A1,C[C@@]1(c2cc(F)cc(F)c2)CNC2(CCCC2)C(=O)N1C/C=C/c1ccc2c(c1)CC1(C2)C(=O)Nc2ncccc21>>C[C@@]1(c2cc(F)cc(F)c2)CNC2(CCCC2)C(=O)N1CCCc1ccc2c(c1)C[C@@]1(C2)C(=O)Nc2ncccc21,[Pd],CO,,,,test
US20120010207A1,Cc1ccc(-c2c(F)c(Cl)cc(C(=O)[O-])c2F)cc1.Oc1ccc(C(F)(F)F)c(Cl)c1>>Cc1ccc(OC(=O)c2cc(Cl)c(Oc3ccc(C(F)(F)F)c(Cl)c3)cc2F)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140045862A1,COc1ccc(CN(c2ccncn2)S(=O)(=O)c2cc(Cl)c(O[C@@H]3CCC[C@H]3c3ccn(C4CCCCO4)n3)cc2F)c(OC)c1>>O=S(=O)(Nc1ccncn1)c1cc(Cl)c(O[C@@H]2CCC[C@H]2c2ccn[nH]2)cc1F,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20030166639A1,CC(C)(C)OC(=O)Nc1ccc(OCC(F)(F)F)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1ccc(OCC(F)(F)F)cc1N,[Pd],,,,,test
US20150291527A1,CCOC(=O)c1cccc(O)n1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)c1cccc(S)n1,,C1CCOC1,,O,,test
US20100093724A1,CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(C#N)c1.[N-]=[N+]=[N-]>>CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(-c2nnn[nH]2)c1,,CC#N,O,CN(C)C=O,,test
US05965539,CC(C)(C)OC(=O)N[C@H](C=O)CSC(c1ccccc1)(c1ccccc1)c1ccccc1.COC(=O)[C@H](CCSC)NC(=O)c1ccc(N)cc1-c1ccccc1>>COC(=O)[C@H](CCSC)NC(=O)c1ccc(NC[C@H](CSC(c2ccccc2)(c2ccccc2)c2ccccc2)NC(=O)OC(C)(C)C)cc1-c1ccccc1,,CO,,Cl,[BH3-]C#N.[Na+],test
US20050154028A1,COC(C=O)OC.COc1ccc(N)cc1OCCN1CCCCC1>>COc1ccc(NCC(OC)OC)cc1OCCN1CCCCC1,[Pd],CCO,,,,test
US20110077235A1,Nc1cc(N2CCOCC2)n2nccc2n1.O=C(O)C1CC1>>O=C(Nc1cc(N2CCOCC2)n2nccc2n1)C1CC1,,c1ccncc1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080234255A1,CC(C)(C)OC(=O)CCN(c1nc(Cl)ncc1[N+](=O)[O-])C1CCCCC1>>O=C1CCN(C2CCCCC2)c2nc(Cl)ncc2N1,,CCOC(C)=O,O,CCO,Cl,test
US04091211,C=C1CC(=O)O1.CCNC(N)=S>>CCn1c(C)cc(=O)nc1S,,CC(=O)O,,,,test
US20010039293A1,CCOC(=O)c1c(F)cc(NC(=O)c2cc3c(cc2O)C(C)(C)CCC3(C)C)cc1F.O=S(=O)(Cl)Cl>>CCOC(=O)c1c(F)cc(NC(=O)c2cc3c(c(Cl)c2O)C(C)(C)CCC3(C)C)cc1F,,ClCCl,,CCOCC,,test
US20060235033A1,COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1N.Cc1csc(C(C)N)n1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NC(C)c1nc(C)cs1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US04007276,O=[N+]([O-])c1cccc(-c2nc3n(n2)Cc2ccccc2-3)c1>>Nc1cccc(-c2nc3n(n2)Cc2ccccc2-3)c1,[Pd],,,Cl,,test
US20040127492A1,COC(=O)C(=O)OC.COc1ccc2c(c1)CC(C)CC2=O>>COC(=O)/C(O)=C1/C(=O)c2ccc(OC)cc2CC1C,,CCOCC,CO,Cl,C[O-].[Na+],test
US20040127574A1,Brc1ccccn1.O=C(OCc1ccccc1)c1ccc(O)cc1>>O=C(OCc1ccccc1)c1ccc(Oc2ccccn2)cc1,[Cu],CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20090298807A1,CC(C)(C)[Si](C)(C)OCCc1csc(CN2CCC3(CC2)CN(C(=O)C(F)(F)F)CCO3)c1>>O=C(N1CCOC2(CCN(Cc3cc(CCO)cs3)CC2)C1)C(F)(F)F,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04695569,Fc1ccc(Cn2c(NC3CCN(CCCl)CC3)nc3ccccc32)cc1.Sc1nc2cccnc2s1>>Fc1ccc(Cn2c(NC3CCN(CCSc4nc5cccnc5s4)CC3)nc3ccccc32)cc1,,O,,CN(C)C=O,[H-].[Na+],test
US20050059607A1,C1CCOC1.CC(=O)N1CC(O)CC1C(=O)O.N=C(N)NCCCC(N)C(=O)c1nc2ccccc2s1>>CC(C)N=C=NC(C)C,,C1CCOC1,O,,,test
US20120238541A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccccc4)oc4c(Cl)nccc4c3=O)cc2)CCC1.c1nc[nH]n1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccccc4)oc4c(-n5cnnc5)nccc4c3=O)cc2)CCC1,[Cu]I,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150284343A1,CCOC(=O)c1nnn(Cc2ccc(OC)cc2)c1Cl.Oc1cccc(OC(F)(F)F)c1>>CCOC(=O)c1nnn(Cc2ccc(OC)cc2)c1Oc1cccc(OC(F)(F)F)c1,,CN(C)C=O,,[H-].[Na+],,test
US20060223761A1,CN(C)CCCO.COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C.C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O>>COC(=O)[C@H](Cc1ccc(OCCCN(C)C)cc1)NC(=O)[C@H](C)NC(=O)Cc1cc(F)cc(F)c1,,CO,ClCCl,,,test
US20040082643A1,CC(C)(C)[Si](C)(C)Cl.Cc1ccc(Br)c2c(CCO)c[nH]c12>>Cc1ccc(Br)c2c(CCO[Si](C)(C)C(C)(C)C)c[nH]c12,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US20090131468A1,COC(=O)c1ccc(-c2nc3cccnc3o2)cc1>>O=C(O)c1ccc(-c2nc3cccnc3o2)cc1,,C1CCOC1,CO,[Li+].[OH-],,test
US20020049210A1,O=C(C=CC1CCN(Cc2ccccc2)CC1)c1cc2ccccc2o1>>O=C(CCC1CCN(Cc2ccccc2)CC1)c1cc2ccccc2o1,O=[Pt],CCO,CCOC(C)=O,,,test
US20080009515A1,CCOC(=O)c1cnc(Cl)c2c(CBr)csc12.COc1ccc(Cn2nnc(-c3cccc(O)c3)n2)cc1>>CCOC(=O)c1cnc(Cl)c2c(COc3cccc(-c4nnn(Cc5ccc(OC)cc5)n4)c3)csc12,,C1CCOC1,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110098302A1,COC(=O)Cc1cccc(Oc2ccc(Br)cc2C=O)c1.N[C@H](CO)Cc1ccccc1>>COC(=O)Cc1cccc(Oc2ccc(Br)cc2CN[C@H](CO)Cc2ccccc2)c1,CC(=O)O,ClCCl,,[BH3-]C#N.[Na+],,test
US20140213586A1,COc1cccc(NC(C(=O)c2nn(CCOC3CCCCO3)c3ccccc23)c2ccccc2)c1>>COc1cccc(NC(C(=O)c2nn(CCO)c3ccccc23)c2ccccc2)c1,,CC#N,,Cl,,test
US20150099771A1,COC(=O)C1=C(O)c2ncccc2CC(c2ccccc2)O1>>O=C1COC(c2ccccc2)Cc2cccnc21,,CS(C)=O,O,[Cl-].[Na+],,test
US20120122907A1,COc1ccc(Cn2cc(-c3csc(O)n3)c(C)n2)cc1.Clc1ncccn1>>COc1ccc(Cn2cc(-c3csc(Oc4ncccn4)n3)c(C)n2)cc1,[Cu],CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080132546A1,CCNC(=O)Nc1ccc(-c2nc(C(=O)N(C)C)c(C(=O)OCC)s2)cn1>>CCNC(=O)Nc1ccc(-c2nc(C(=O)N(C)C)c(C(=O)O)s2)cn1,,CO,,[Li+].[OH-],,test
US20080312270A1,CC(=O)CC(C)=O.Nc1ccc(F)cc1N>>Cc1nc2cc(F)ccc2[nH]1,,CCO,,Cl,O=C([O-])O.[Na+],test
US07179823B1,O=Cc1cccc(OCCBr)c1.O=c1[nH]ncc2ccccc12>>O=Cc1cccc(OCCn2ncc3ccccc3c2=O)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20060106048A1,CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)OC)c(NC(=O)C(F)(F)F)c1)=NC(C)(C)C2.N#Cc1ccc(CBr)cc1>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)OC)c(N(Cc3ccc(C#N)cc3)C(=O)C(F)(F)F)c1)=NC(C)(C)C2,,CN(C)C=O,,[I-].[K+],,test
US04803206,NCCN.Nc1nc(N)c(C(=O)O)nc1Cl>>NCCNC(=O)c1nc(Cl)c(N)nc1N,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20080221114A1,C1CCNC1.O=C(O)C1Cc2ccccc2N1c1ncccn1>>O=C(C1Cc2ccccc2N1c1ncccn1)N1CCCC1,,C1CCOC1,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20090186879A1,C=CCn1c(=O)[nH]c2c(Cl)ccc(C(CC)CC)c21.O=P(Cl)(Cl)Cl>>C=CCn1c(Cl)nc2c(Cl)ccc(C(CC)CC)c21,,CCOC(C)=O,,,,test
US20100076029A1,CC(=O)OC(C)=O.CC(C)(CO)c1cc(NC(=O)C(C)(C)S(=O)(=O)C2CCOCC2)on1>>CC(=O)OCC(C)(C)c1cc(NC(=O)C(C)(C)S(=O)(=O)C2CCOCC2)on1,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20070259854A1,COC1=NCCCCC1.Cc1csc(C2(C(=O)NN)CCCC2)c1Cl>>Cc1csc(C2(c3nnc4n3CCCCC4)CCCC2)c1Cl,,Cc1ccccc1,,C1COCCO1,,test
US20030114456A1,CS(=O)(=O)c1ccc(-n2cncc2-c2ccc(F)cc2)cc1.O=C1CCC(=O)N1Cl>>CS(=O)(=O)c1ccc(-n2cnc(Cl)c2-c2ccc(F)cc2)cc1,,ClC(Cl)Cl,,,,test
US20080234384A1,COC(=O)c1ccccc1Sc1ccccc1C(=O)OC>>OCc1ccccc1Sc1ccccc1CO,,C1CCOC1,CCOCC,[H-].[Na+],,test
US20130029971A1,CCOC(=O)CC1CCN(c2ncc(C#N)cc2NC(=O)c2cccc(Cl)c2)CC1>>N#Cc1cnc(N2CCC(CC(=O)O)CC2)c(NC(=O)c2cccc(Cl)c2)c1,,C1CCOC1,CO,O,[Li+].[OH-],test
US20070249649A1,CC1(C)CC=C(B(O)O)CC1.Nc1ccc(CC(=O)NCCCO)cc1Br>>CC1(C)CC=C(c2cc(CC(=O)NCCCO)ccc2N)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20110086834A1,C#C[Mg]Br.CC(=O)c1ccn(C)n1>>C#CC(C)(O)c1ccn(C)n1,,C1CCOC1,,,,test
US20050032786A1,CC(C)(C)OC(=O)CCc1ccc(C#N)nc1.COC(=O)c1ccccc1S>>CC(C)(C)OC(=O)CCc1ccc(-c2nc(=O)c3ccccc3s2)nc1,,Cc1ccccc1,,CCN(CC)CC,,test
US05308857,CN.CSC(=NC#N)SC.NCc1ccc(-c2csc(N=C(N)N)n2)o1>>CNC(=NC#N)NCc1ccc(-c2csc(N=C(N)N)n2)o1,,CN(C)C=O,,,,test
US20040102436A1,CN.[O-][n+]1cc(Cl)nc(-c2ccccc2)c1-c1ccccc1>>CNc1c[n+]([O-])c(-c2ccccc2)c(-c2ccccc2)n1,,CO,,,,test
US06124323,CO.O=C(O)c1cc(OCCOCc2ccccc2)ccc1[N+](=O)[O-].[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COC(=O)Nc1cc(OCCOCc2ccccc2)ccc1[N+](=O)[O-],,C1CCOC1,c1ccccc1,CCN(CC)CC,,test
US20140023611A1,O=[N+]([O-])c1ccc(N2CCCCC2)cc1-c1cc(Cl)ncn1.Oc1cccc(C(F)(F)F)c1>>O=[N+]([O-])c1ccc(N2CCCCC2)cc1-c1cc(Oc2cccc(C(F)(F)F)c2)ncn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120035157A1,Cc1c(C(=O)N(N)C(=O)C(C)C)cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n1-c1cccc(C(F)(F)F)c1>>Cc1c(-c2nnc(C(C)C)o2)cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n1-c1cccc(C(F)(F)F)c1,,ClCCl,,,,test
US20110021351A1,COC(=O)c1nccnc1N.O=C(O)Cc1ncc(Cl)cc1Cl>>COC(=O)c1nccnc1NC(=O)Cc1ncc(Cl)cc1Cl,,ClCCl,,CCN(CC)CC,O=C1OCCN1P(=O)(Cl)N1CCOC1=O,test
US20060003995A1,CC(NC(=O)OC(C)(C)C)C(=O)Nc1ccc(Br)cc1C(=O)c1ccccc1F>>CC1N=C(c2ccccc2F)c2cc(Br)ccc2NC1=O,,ClC(Cl)Cl,,Cl,,test
US20090181928A1,O=C1CN(c2ccc(CC3CCCC3)cc2OCc2ccccc2)S(=O)(=O)N1>>O=C1CN(c2ccc(CC3CCCC3)cc2O)S(=O)(=O)N1,[Pd],CCO,,O,,test
US20130165464A1,COc1ccc(CNc2cc(-n3cc(-c4ccccc4Cl)c(-c4nccn4COCC[Si](C)(C)C)c3)c(C)cn2)c(OC)c1.O=C(Cl)C1CC1>>COc1ccc(CN(C(=O)C2CC2)c2cc(-n3cc(-c4ccccc4Cl)c(-c4nccn4COCC[Si](C)(C)C)c3)c(C)cn2)c(OC)c1,,ClCCl,O,CCN(C(C)C)C(C)C,,test
US20160075713A1,Cc1ccc(C(F)(F)C(=O)N2CCC(N)CC2)cn1>>Cc1ccc(C(F)(F)CN2CCC(N)CC2)cn1,,C1CCOC1,,B,Cl,test
US20140288045A1,C=Cc1ccc(OC)cc1Cl.C[Si](C)(C)C(F)(F)F>>COc1ccc(C2CC2(F)F)c(Cl)c1,,C1CCOC1,CCCCCC,[I-].[Na+],,test
US07960377B2,CC(C)(C)NC(=O)c1cnc2c(c1)N(C(=O)OC(C)(C)C)CCO2>>CC(C)(C)NC(=O)c1cnc2c(c1)NCCO2,,CN(C)C=O,ClCCl,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US04178460,BrBr.Cc1ccc(SC(F)(F)F)cc1>>FC(F)(F)Sc1ccc(CBr)cc1,,ClC(Cl)(Cl)Cl,,,,test
US20030125266A1,CCOC(=O)C(C)(C)Br.c1cncc(-c2c[nH]cn2)c1>>CCOC(=O)C(C)(C)n1cnc(-c2cccnc2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050101615A1,COC(=O)CC(=O)OC.COc1ccc(CNc2nc(SC)ncc2C=O)cc1Cl>>COC(=O)c1cc2cnc(SC)nc2n(Cc2ccc(OC)c(Cl)c2)c1=O,,CCOC(C)=O,,C1CCNCC1,CC(=O)O,test
US20130029961A1,CN(C)c1ncc([N+](=O)[O-])cc1C(F)(F)F>>CN(C)c1ncc(N)cc1C(F)(F)F,[Pd],CO,,,,test
US06610697B1,CCOC(=O)c1ccccc1.CSc1nccc(C)n1>>CSc1nccc(CC(=O)c2ccccc2)n1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20140179668A1,CC(C)c1cc(Nc2nc(Cl)nc3c2CCC3)n[nH]1.O=C(O)[C@@H]1CCCN1>>CC(C)c1cc(Nc2nc(N3CCCC3C(=O)O)nc3c2CCC3)n[nH]1,,C1COCCO1,,CCN(C(C)C)C(C)C,[Na+].[OH-],test
US04788186,CNCC(C)O.Clc1ccc2c(c1)c(-c1ccccc1)nn1c(Cl)nnc21>>CC(O)CN(C)c1nnc2c3ccc(Cl)cc3c(-c3ccccc3)nn12,,CCO,ClC(Cl)Cl,,,test
US05521167,CC(C)(C)[Si](C)(C)Cl.C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](SCCO)CC[C@@]43C)[C@@H]1CCC2=O>>CC(C)(C)[Si](C)(C)OCCS[C@H]1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CCC(=O)[C@@]4(C)CC[C@@H]32)C1,,CN(C)C=O,,O,c1c[nH]cn1,test
US20090240052A1,Cc1cccc(C(=O)Nc2cc(-c3cccc(Cl)c3)ccc2C(=O)OC(C)(C)C)c1C>>Cc1cccc(C(=O)Nc2cc(-c3cccc(Cl)c3)ccc2C(=O)O)c1C,,O=C(O)C(F)(F)F,,,,test
US20150087646A1,CC(C)C(=O)Cl.NCc1cc(-c2nn(-c3ccc(C(F)(F)F)cc3)c(=O)[nH]2)c(Cl)cc1F>>CC(C)C(=O)NCc1cc(-c2nn(-c3ccc(C(F)(F)F)cc3)c(=O)[nH]2)c(Cl)cc1F,,C1CCOC1,,,,test
US06271264B1,C1CCCNCC1.C=CCBr>>C=CCN1CCCCCC1,,CCOCC,,,,test
US20110275637A1,Cc1ccnc(C)c1CO.O=C(Oc1ccc([N+](=O)[O-])cc1)Oc1ccc([N+](=O)[O-])cc1>>Cc1ccnc(C)c1COC(=O)Oc1ccc([N+](=O)[O-])cc1,,ClCCl,,CN1CCOCC1,,test
US20100286145A1,COC(OC)c1cncc(C(C)=O)c1>>CC(=O)c1cncc(C=O)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100204250A1,CC(C)=CCn1c(N2CCCC(NC(=O)OC(C)(C)C)C2)nc2c1c(=O)n(CC(=O)c1cccc(O)c1)c(=O)n2C.OB(O)Oc1ccccc1>>CC(C)=CCn1c(N2CCCC(NC(=O)OC(C)(C)C)C2)nc2c1c(=O)n(CC(=O)c1cccc(Oc3ccccc3)c1)c(=O)n2C,,ClCCl,,c1ccncc1,,test
US20080207654A1,CCCc1nc(CC)n(-c2cccc(C(C)=O)c2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.[Li]C>>CCCc1nc(CC)n(-c2cccc(C(C)(C)O)c2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1,,C1CCOC1,,[Cl-].[NH4+],,test
US20060111351A1,CC(C)(C)OC(=O)n1c(B(O)O)cc2ccccc21.O=C(c1ccncc1)c1cc(Cl)ccc1NS(=O)(=O)c1ccc(Br)cc1>>CC(C)(C)OC(=O)n1c(-c2ccc(S(=O)(=O)Nc3ccc(Cl)cc3C(=O)c3ccncc3)cc2)cc2ccccc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20160068512A1,O=C(O)c1ccc(S(=O)(=O)Cl)cc1.OCCOc1nc(NC2CCNCC2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2n1>>O=C(O)c1ccc(S(=O)(=O)N2CCC(Nc3nc(OCCO)nc4ccc(C(c5ccc(Cl)cc5)c5ccc(Cl)cc5)cc34)CC2)cc1,,ClCCl,,CCN(CC)CC,,test
US20140163000A1,CN1CCNCC1.O=[N+]([O-])c1cncc(Br)c1Cl>>CN1CCN(c2c(N)cncc2Br)CC1,[Fe],CC(=O)O,ClCCl,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20150218187A1,COC(=O)CC1CCC2(CC=C(c3ccc([N+](=O)[O-])cn3)CC2)CC1>>COC(=O)CC1CCC2(CC1)CCC(c1ccc(N)cn1)CC2,[Pd],CCOC(C)=O,,,,test
US20020028807A1,CCN1c2ncc(CCOc3ccnc4ccccc34)cc2C(=O)N(C)c2ccc(F)nc21.O=C(OO)c1cccc(Cl)c1>>CCN1c2ncc(CCOc3cc[n+]([O-])c4ccccc34)cc2C(=O)N(C)c2ccc(F)nc21,,ClCCl,,,,test
US20130225620A1,Clc1nccc(Nc2cc(C3CC3)n[nH]2)n1.NCc1cccc2c1cnn2C1CCCCO1>>c1cc(CNc2nccc(Nc3cc(C4CC4)[nH]n3)n2)c2cnn(C3CCCCO3)c2c1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20150141400A1,CCOC(=O)[C@@H]1CCCNC1.CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(C=O)c(C(F)(F)F)cc2c1=O>>CCOC(=O)[C@@H]1CCCN(Cc2c(C(F)(F)F)cc3c(=O)n(Cc4cc(Cl)ccc4S(=O)(=O)CC)c(=O)[nH]c3c2Cl)C1,,ClC(Cl)Cl,,,,test
US20160251339A1,COc1c(N2CCN(C(=O)C(Cl)(Cl)Cl)CC2)cc(S(=O)(=O)n2cc(C)c3ccc(Cl)cc32)c2ccccc12>>COc1c(N2CCNCC2)cc(S(=O)(=O)n2cc(C)c3ccc(Cl)cc32)c2ccccc12,,C1CCOC1,,[K+].[OH-],,test
US07179823B1,CCOC(=O)c1c[nH]nc1-c1cccs1.Cc1oc(-c2ccccc2)nc1COc1ccc(CCl)cc1>>CCOC(=O)c1cn(Cc2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)nc1-c1cccs1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150018363A1,CCOC(=O)c1nc2ccc(I)cn2c1C>>Cc1c(C(=O)O)nc2ccc(I)cn12,,C1CCOC1,O,[Li+].[OH-],,test
US04985419,CC(C)N(C)CC(C)N1c2ccccc2Sc2ccc(C(N)=S)cc21.CCCN.Cl>>CCCNC(=S)c1ccc2c(c1)N(C(C)CN(C)C(C)C)c1ccccc1S2.Cl,,CCO,,,,test
US06476038B1,COc1ccc(-c2c(C)nn3c(O)cc(C)nc23)c(OC)c1.O=P(Cl)(Cl)Cl>>COc1ccc(-c2c(C)nn3c(Cl)cc(C)nc23)c(OC)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20120329830A1,COc1ccc(CNc2nc3ccc(-n4ccnc4C)cc3cc2CCC(=O)NCC2CCCCC2)cc1>>Cc1nccn1-c1ccc2nc(N)c(CCC(=O)NCC3CCCCC3)cc2c1,,O=C(O)C(F)(F)F,,,,test
US04797401,CC(=O)N1CCN(c2ccc([N+](=O)[O-])c(C)c2)CC1>>CC(=O)N1CCN(c2ccc(N)c(C)c2)CC1,[Pd],CCO,,,,test
US20080175794A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.COc1ncc(C(F)(F)F)c(Cl)n1>>COc1ncc(C(F)(F)F)c(C(C)=O)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20010056123A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(C(=O)O)cc2)CC1.N#Cc1ccc(OCc2ccccc2)c(OCCN)c1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(C(=O)NCCOc3cc(C#N)ccc3OCc3ccccc3)cc2)CC1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20140121231A1,CC1(C(=O)O)CC1.O=c1[nH]c2c(c3ccccc13)COC(C1CC[NH2+]CC1)C2>>CC1(C(=O)N2CCC(C3Cc4[nH]c(=O)c5ccccc5c4CO3)CC2)CC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US04666907,CC(=O)OC(C)=O.Oc1ccc2c(c1Cl)Sc1ccccc1N2>>CC(=O)Oc1ccc2c(c1Cl)Sc1ccccc1N2,,O,,c1ccncc1,,test
US20110086843A1,CC(=O)Nc1nc(C)c(-c2cc(S(=O)(=O)N3CCC(O)CC3)sc2Br)s1>>CC(=O)Nc1nc(C)c(-c2csc(S(=O)(=O)N3CCC(O)CC3)c2)s1,,C1CCOC1,,[Li]CCCC,,test
US20040077896A1,CC1(C)OC(=O)CC(=O)O1.O=C(Cl)Cc1ccc(OCc2c(F)cccc2F)cc1.c1ccncc1>>CCOC(=O)CC(=O)Cc1ccc(OCc2c(F)cccc2F)cc1,,ClCCl,,Cl,,test
USRE028865,O=c1cc[nH]c(=O)[nH]1.OC(c1ccccc1)c1ccc(Cl)cc1Cl>>Oc1ncc(C(c2ccccc2)c2ccc(Cl)cc2Cl)c(O)n1,,CC(=O)O,,FB(F)F,,test
US04530841,CI.O=C(OCc1ccccc1)C1=C(Cl)CC2CC(=O)N12>>CC1C(=O)N2C(C(=O)OCc3ccccc3)=C(Cl)CC12,,C1CCOC1,CCOC(C)=O,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20100330700A1,CCOC(=O)CNC(=O)[C@@H](NC(=O)OC(C)(C)C)[C@@H](C)O>>C[C@@H](O)[C@H](NC(=O)OC(C)(C)C)C(=O)NCC(=O)O,,CO,,Cl,[Na+].[OH-],test
US20120058288A1,CC(C)C[Al](CC(C)C)CC(C)C.CCO>>CC(C)C[Al+]CC(C)C.CC[O-],,CCCCCC,,,,test
US06100260,CC(C)(c1cccc(C2(c3ccccc3)OCCO2)c1)c1cc(N=C(N)N2CCOCC2)on1>>CC(C)(c1cccc(C(=O)c2ccccc2)c1)c1cc(N=C(N)N2CCOCC2)on1,,CC(=O)O,,,,test
US20140094445A1,CC1CCNCC1.O=C(O)c1cccc(S(=O)(=O)Cl)c1>>CC1CCN(S(=O)(=O)c2cccc(C(=O)O)c2)CC1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US04845110,C[Si](C)(C)Cl.N#Cc1cccc(CCC=O)c1>>C[Si](C)(C)OC=CCc1cccc(C#N)c1,,CN(C)C=O,,CCN(CC)CC,,test
US20070021454A1,COc1cccc([C@H]2CCC[C@H]2N2C(=O)c3ccccc3C2=O)c1>>COc1cccc([C@H]2CCC[C@H]2N)c1,,Cc1ccccc1,,NN,,test
US05177106,CC(=O)O.COC(=O)C(C)(C)CCCOc1cc(C)c([N+](=O)[O-])cc1C>>COC(=O)C(C)(C)CCCOc1cc(C)c(NC(C)=O)cc1C,[Fe],,,,,test
US20020037888A1,BrCc1ccccc1.CCC1(c2cccc(O)c2)CCCCNC1=O>>CCC1(c2cccc(OCc3ccccc3)c2)CCCCNC1=O,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150112067A1,CC#N.C[C@@H]1[C@H](c2ccccc2)C[C@H](NC(=O)c2cnc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C(=O)N1CC(F)(F)F.O>>CC#N.C[C@@H]1[C@H](c2ccccc2)C[C@H](NC(=O)c2cnc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C(=O)N1CC(F)(F)F.O,,O,,CC#N,,test
US20050009799A1,CC1(CO)CC=C(c2ccc(OCc3ccccc3)cc2)CC1>>CC1(CO)CC=C(c2ccc(O)cc2)CC1,,ClCCl,,ClB(Cl)Cl,,test
US05635571,COC(=O)c1ccc(C(=O)Cl)cc1.NCCO>>COC(=O)c1ccc(C(=O)NCCO)cc1,,ClCCl,,,,test
US20060004078A1,COC(=O)C(C(=O)OC)c1ccc([N+](=O)[O-])cc1.COCCOCCO>>COCCOCCC(C(=O)OC)(C(=O)OC)c1ccc([N+](=O)[O-])cc1,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090124663A1,CI.O=C(NC1CCN(c2ccc(Cl)c(Cl)c2)CC1)C(F)(F)F>>CN(C(=O)C(F)(F)F)C1CCN(c2ccc(Cl)c(Cl)c2)CC1,,C1CCOC1,,O,[H-].[Na+],test
US05556860,Nc1ccc(Cl)cc1C(=O)c1ccccc1.O=C(Cl)C(Cl)(Cl)Cl>>O=C(c1ccccc1)c1cc(Cl)ccc1NC(=O)C(Cl)(Cl)Cl,,C1CCOC1,,CCN(CC)CC,O,test
US20040147561A1,CN(C)C=C(C=O)OCc1ccccc1.NC(=O)Cc1csc(-c2ccncc2)n1>>O=c1[nH]cc(OCc2ccccc2)cc1-c1csc(-c2ccncc2)n1,,CN(C)C=O,CO,[H-].[Na+],,test
US20120136000A1,CN1CCNCC1.Fc1ccc(F)c(-c2n[nH]c3ncccc23)n1>>CN1CCN(c2ccc(F)c(-c3n[nH]c4ncccc34)n2)CC1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US20100125089A1,CC(N)(C#N)Cn1cc2c(Cl)cc(Cl)c(Cl)c2n1.O=C(Cl)c1cccc(Br)c1>>CC(C#N)(Cn1cc2c(Cl)cc(Cl)c(Cl)c2n1)NC(=O)c1cccc(Br)c1,,C1CCOC1,,,,test
US20070287725A1,CCOCc1nc2c(N)nc3cccnc3c2n1Cc1cc(-c2ccc(F)cc2)no1>>Nc1nc2cccnc2c2c1nc(CO)n2Cc1cc(-c2ccc(F)cc2)no1,,ClCCl,,BrB(Br)Br,CO,test
US20020143035A1,COC(=O)[C@@H]1C[C@H](Oc2ccc(Br)cc2)CN1.O=C=Nc1cc(Cl)cc(Cl)c1>>O=C1[C@@H]2C[C@H](Oc3ccc(Br)cc3)CN2C(=O)N1c1cc(Cl)cc(Cl)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080188473A1,CCOC(=O)c1c(NCCCc2ccccc2)c2cc(-c3ccc(OC(C)C)cc3)ccc2n1-c1ccc(OC(C)C)cc1.O=C(Cl)c1ccc(OC(F)(F)F)cc1>>CCOC(=O)c1c(N(CCCc2ccccc2)C(=O)c2ccc(OC(F)(F)F)cc2)c2cc(-c3ccc(OC(C)C)cc3)ccc2n1-c1ccc(OC(C)C)cc1,,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US20070066588A1,CI.c1cc2nc([C@@H]3C[C@@H](N4CCCCC4)C3)sc2cc1-c1cn[nH]c1>>Cn1cc(-c2ccc3nc([C@@H]4C[C@@H](N5CCCCC5)C4)sc3c2)cn1,,CN(C)C=O,,[H-].[Na+],,test
US20020132796A1,COC(=O)Cc1ccc(C#Cc2ccc(C(C)(C)O[SiH2]C(C)(C)C)c(C(C)C)c2)cc1>>COC(=O)Cc1ccc(C#Cc2ccc(CO)c(C(C)C)c2)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090066231A1,CCN(CC)CC.N=C([O-])c1ccc(Br)cc1.O=C(Cl)c1cccc2ccccc12>>CCOC(=NC(=O)c1cccc2ccccc12)c1ccc(Br)cc1,,Cc1ccccc1,,,,test
US20030232863A1,COC(=O)[C@H](CCC(F)(F)F)NC(=O)OCc1ccccc1>>O=C(N[C@H](CO)CCC(F)(F)F)OCc1ccccc1,,C1CCOC1,,[BH4-].[Li+],,test
US20160272637A1,CCOC(=O)c1cn2ccc([N+](=O)[O-])cc2n1.N>>NC(=O)c1cn2ccc([N+](=O)[O-])cc2n1,,CCOC(C)=O,O,Cl,,test
US20090286791A1,COC(OC)OC.NC(=NO)c1ccc(C(=O)NCCNC(=O)c2cn(-c3ccccc3)nc2C(F)(F)F)cn1>>O=C(NCCNC(=O)c1cn(-c2ccccc2)nc1C(F)(F)F)c1ccc(-c2ncon2)nc1,,CCOC(C)=O,,,,test
US20140349994A1,COCCN1CCC(Br)C(=O)c2cn(Cc3ccc(OC)cc3)nc21.NC(N)=S>>COCCN1CCc2sc(N)nc2-c2cn(Cc3ccc(OC)cc3)nc21,,CC(C)=O,CCO,,,test
US20130072467A1,C#CCNC1=NC(=O)SC1.CC(c1ccc(C(F)(F)F)cc1C(F)(F)F)N1CCC(C=O)CC1>>C#CCNC1=NC(=O)S/C1=C\C1CCN(C(C)c2ccc(C(F)(F)F)cc2C(F)(F)F)CC1,,CC(C)O,CCOC(C)=O,C1CC[NH2+]CC1.CC(=O)[O-],,test
US20120225854A1,CCOC(=O)[C@H](Cc1cccnc1OC)NC(=O)CN>>COc1ncccc1CC1NC(=O)CNC1=O,,CO,,CCN(C(C)C)C(C)C,,test
US20020137736A1,CO.O=C(NCCF)c1cc([N+](=O)[O-])ccc1Cl>>COc1ccc([N+](=O)[O-])cc1C(=O)NCCF,,CO,,C[O-].[Na+],,test
US20140228386A1,Brc1ccc2sccc2c1.O=C1NCCN1c1cnccc1C1CC1>>O=C1N(c2ccc3sccc3c2)CCN1c1cnccc1C1CC1,I[Cu]I,,,CN[C@@H]1CCCC[C@H]1NC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20090076078A1,CCOC(=O)N1CCC(C)(N2CCC(=O)CC2)CC1.N[C@H]1CCCC[C@@H]1N>>CCOC(=O)N1CCC(C)(N2CCC(N[C@H]3CCCC[C@@H]3N)CC2)CC1,,ClCCl,,O=C([O-])O.[Na+],,test
US20130190316A1,CN(C)C=O.O=C1Cc2ccccc2CN1.O=P(Cl)(Cl)Cl>>O=Cc1c(Cl)ncc2ccccc12,,C1CCOC1,Cc1ccccc1,[Na+].[OH-],,test
US04639521,CC(=O)c1ncc[nH]1.O=C1CCC(c2ccncc2)CC1>>CC(=O)C1CC(c2ccncc2)CCC1=O,,C1CCOC1,CCCCCC,CC(C)NC(C)C,[Li]CCCC,test
US20140343277A1,Cc1cc2c(=O)n(CC(O)O)ccc2o1.Nc1ccccc1N>>Cc1cc2c(=O)n(Cc3nc4ccccc4[nH]3)ccc2o1,,CCO,,O,,test
US20130225561A1,COC(=O)CC(=O)OC(C)(C)C.N#Cc1ccc(F)c(Cl)c1F>>COC(=O)C(C(=O)OC(C)(C)C)c1ccc(C#N)c(F)c1Cl,,CN(C)C=O,,[H][H],[H-].[Na+],test
US05059609,COc1cccc(O[C@@H]2COc3ccc(O)cc3[C@@H]2O)c1.ClCc1ccccn1>>COc1cccc(O[C@@H]2COc3ccc(OCc4ccccn4)cc3[C@@H]2O)c1,,ClCCl,,,,test
US20150307522A1,Brc1cnsc1.COC(=O)C#N>>COC(=O)c1sncc1Br,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20090130165A1,O=C(Cl)CCl.O=c1[nH]c2ccc(Cl)cc2[nH]1>>O=C(CCl)c1cc2[nH]c(=O)[nH]c2cc1Cl,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20050171103A1,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(Br)c(F)c1.OB(O)c1cccnc1>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(-c2cccnc2)c(F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])O.[Na+],,test
US20070244119A1,CCN(C(C)C)C(C)C.CN(c1cc(C(=O)O)cc(-c2nnc(C(C)(Cc3ccccc3)NC(=O)OC(C)(C)C)o2)c1)S(C)(=O)=O.On1nnc2cccnc21>>CON(C)C(=O)c1cc(-c2nnc(C(C)(Cc3ccccc3)NC(=O)OC(C)(C)C)o2)cc(N(C)S(C)(=O)=O)c1,,ClC(Cl)Cl,,ClCCCl,,test
US20050165042A1,Clc1cc(Cl)cc(Cl)c1.O=C(Br)CBr>>O=C(CBr)c1c(Cl)cc(Cl)cc1Cl,,CCOC(C)=O,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US06657031B1,O=C(O)C1CC=CCC1.O=S(Cl)Cl>>O=C(Cl)C1CC=CCC1,CN(C)C=O,Cc1ccccc1,,,,test
US20070003539A1,C1CCNC1.CC(C)S(=O)(=O)c1ccc(N)cc1C#N.O=C(Cl)Cl>>CC(C)S(=O)(=O)c1ccc(NC(=O)N2CCCC2)cc1C#N,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20090088322A1,CCOC(=O)c1nc(C2CC2)nc(N)c1Br.C[Sn](C)(C)C>>CCOC(=O)c1nc(C2CC2)nc(N)c1C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,ClCCCl,,,,test
US20080176830A1,CCSC(=O)C1Cc2cc(-c3ccc(C(F)(F)F)cc3)ccc2N(C(=O)OC(C)(C)C)C1=O>>CCSC(=O)C1Cc2cc(-c3ccc(C(F)(F)F)cc3)ccc2NC1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030216325A1,C=CCC1(C)C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1>>CCCC1(C)C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1,[Pd],CO,,,,test
US04703130,COCCOCCOCCCCCCCCO.Cc1ccc(S(=O)(=O)Cl)cc1>>COCCOCCOCCCCCCCCS(=O)(=O)c1ccc(C)cc1,,O,,c1ccncc1,,test
US20030013718A1,Cl.O=c1[nH]nc(CCc2cccnc2)c2ccccc12>>Clc1nnc(CCc2cccnc2)c2ccccc12,,C1COCCO1,CC#N,O=P(Cl)(Cl)Cl,,test
US20140179670A1,CC(=O)c1cnn(-c2ccc(C#N)cc2)c1-c1cn(-c2cccc(C(F)(F)F)c2)c(=O)n(C(C)C)c1=O.C[Mg]Cl>>CC(C)n1c(=O)c(-c2c(C(C)(C)O)cnn2-c2ccc(C#N)cc2)cn(-c2cccc(C(F)(F)F)c2)c1=O,,C1CCOC1,,CCOC(C)=O,O,test
US20100273770A1,CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CN(C(=O)OC(C)(C)C)C(C(=O)O)CO4)no2)cc1Cl.Cl>>CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CNC(C(=O)O)CO4)no2)cc1Cl.Cl,,C1COCCO1,,,,test
US20120135990A1,CC(C)(C)OC(=O)N1CC(Oc2ccc(F)c(F)c2)C2C1CCN2C(=O)C(NC(=O)OCc1ccccc1)C(C)(C)C>>CC(C)(C)C(NC(=O)OCc1ccccc1)C(=O)N1CCC2NCC(Oc3ccc(F)c(F)c3)C21,,ClCCl,,CO,O=C(O)C(F)(F)F,test
US20070249591A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccc(-c2ccc(N)cc2)o1>>CC(C)(C)OC(=O)Nc1ccc(-c2ccc(C(=O)O)o2)cc1,[Pd],CCOC(C)=O,CO,[Na+].[OH-],,test
US20100209340A1,CCCC[Sn](CCCC)(CCCC)c1nccs1.Cc1nc(N)nc2c1cc(Br)c(=O)n2C1CCOC1>>Cc1nc(N)nc2c1cc(-c1nccs1)c(=O)n2C1CCOC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,[F-].[K+],,test
US20030149107A1,Cc1cccc(C)c1COc1cccc(C(=O)CCC(=O)O)c1.N>>Cc1cccc(C)c1COc1cccc(C(=O)CCC(N)=O)c1,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20040259912A1,CC(C)(C)OC(=O)c1cc(N)ccc1OC(c1ccc(F)cc1)c1ccc(F)cc1.COc1ccc(N=C=O)cc1OC>>COc1ccc(NC(=O)Nc2ccc(OC(c3ccc(F)cc3)c3ccc(F)cc3)c(C(=O)OC(C)(C)C)c2)cc1OC,,C1CCOC1,,,,test
US04044138,CC(N)=S.Cc1cnc2c(c1)CCCC2C#N>>Cc1cnc2c(c1)CCCC2CC(N)=S,,CN(C)C=O,,Cl,,test
US05145858,CCOC(=O)Cl.Sc1ccc(-c2nc3n(c2-c2ccncc2)CCC3)cc1>>CCOC(=O)Sc1ccc(-c2nc3n(c2-c2ccncc2)CCC3)cc1,,ClCCl,,CCN(CC)CC,,test
US04785010,CC(=O)CCC(=O)CN1C(=O)c2ccccc2C1=O.CCOC(=O)CCN>>CCOC(=O)CCn1c(C)ccc1CN1C(=O)c2ccccc2C1=O,,CC(=O)O,,CCN(CC)CC,Cl,test
US20060135554A1,CCOc1ccc(CC(=O)O)cc1.O=S(Cl)Cl>>CCOc1ccc(CC(=O)Cl)cc1,,c1ccccc1,,,,test
US20110118236A1,C=C(C)CCl.Oc1ccc(Cl)cc1Br>>C=C(C)COc1ccc(Cl)cc1Br,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040220193A1,CC(C)Br.N#CCc1cccs1>>CC(C)C(C#N)c1cccs1,,CS(C)=O,,O,[K+].[OH-],test
US20020019397A1,C#CCO.O=C(NCc1ccc(Cl)cc1)c1cnc2cnc(Br)nc2c1O>>O=C(NCc1ccc(Cl)cc1)c1cnc2cnc(C#CCO)nc2c1O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,CCN(CC)CC,[Cl-].[NH4+],test
US20120058994A1,CCOC(=O)CN1CCC(N2CCN(C(=O)[C@@H](Cc3cc(Cl)c(N)c(C(F)(F)F)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1.Cl>>CCOC(=O)CN1CCC(N2CCN(C(=O)[C@@H](Cc3cc(Cl)c(N)c(C(F)(F)F)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1.Cl,,C1CCOC1,,,,test
US06476053B1,CCCCCCCCCN1C(=O)C=CC1=O.CCCCCCCCN>>CCCCCCCCCN1C(=O)CC(NCCCCCCCC)C1=O,,CC#N,,CCN(CC)CC,,test
US20080319019A1,COc1ccc(-n2c(-c3ccc(Cl)cc3Cl)nc(C(=O)NN3CCCCC3)c2CO)cc1>>O=C(NN1CCCCC1)c1nc(-c2ccc(Cl)cc2Cl)n(-c2ccc(O)cc2)c1CO,,ClCCl,,BrB(Br)Br,,test
US20060293299A1,BrB(Br)Br.OC(c1ccc(Cl)cc1)c1ccc(Cl)cc1>>Clc1ccc(C(Br)c2ccc(Cl)cc2)cc1,,ClCCl,,O,,test
US05521147,CC1(C)Oc2c(cccc2[N+](=O)[O-])C1=O>>CC1(C)Oc2c(N)cccc2C1=O,[Fe],CC(=O)O,O,,,test
US20080039457A1,CSc1ncc(-c2ccc(Br)c(F)c2)nn1.NN>>NNc1ncc(-c2ccc(Br)c(F)c2)nn1,,CCO,,O,,test
US20140228343A1,BrCC1CO1.CC(C)(C)OC(=O)Nc1cccc(O)c1>>CC(C)(C)OC(=O)Nc1cccc(OCC2CO2)c1,,CN(C)C=O,,[H-].[Na+],,test
US05670493,CCOP(=O)(C=Cc1ccc([N+](=O)[O-])cc1)OCC>>CCOP(=O)(C=Cc1ccc(N)cc1)OCC,[Fe],,,[Cl-].[NH4+],,test
US20150218124A1,COc1cc(C#N)c(Br)c(C#N)c1O.O=C(O)c1cccc(B(O)O)c1>>COc1cc(C#N)c(-c2cccc(C(=O)O)c2)c(C#N)c1O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,CCO,[Na+].[OH-],,test
US20150111877A1,CS(=O)(=O)OS(C)(=O)=O.Cc1nn(C(F)F)cc1S(=O)(=O)N1C[C@H](CO)Cc2ncc(NC(=O)OC(C)(C)C)cc21>>Cc1nn(C(F)F)cc1S(=O)(=O)N1C[C@H](COS(C)(=O)=O)Cc2ncc(NC(=O)OC(C)(C)C)cc21,,ClCCl,,CCN(CC)CC,,test
US20060074084A1,CC(=O)NCCN.CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc3[nH]c(C(=O)O)c(-c4ccccc4)c3c2)cc1>>CC(=O)NCCNC(=O)c1[nH]c2ccc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)cc2c1-c1ccccc1,,CO,ClCCl,,,test
US20100273764A1,C=Cc1cnc(F)c(-c2nc(C)nc3c2ncn3C2CCCCO2)c1.COc1ccc(N)cn1>>C=Cc1cnc(Nc2ccc(OC)nc2)c(-c2nc(C)nc3c2ncn3C2CCCCO2)c1,,C1CCOC1,,O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20150011773A1,CC(C)(C)OC(=O)N[C@@H](CCC(Cc1ccc(O)cc1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.FCCI>>CC(C)(C)OC(=O)N[C@@H](CCC(Cc1ccc(OCCF)cc1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090281081A1,CC(C)(C)OC(=O)N(CCCl)CCCl.N#CC(=O)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)N1CCC(C#N)(c2ccc(Cl)cc2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20050054715A1,COC(=O)c1ccc(/C=C/c2cc(SC)ccc2OC(C)=O)nc1>>COC(=O)c1ccc(/C=C/c2cc(SC)ccc2O)nc1,,CO,,C[O-].[Na+],,test
US20100029697A1,CC(C)(C)c1nc(NN)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2n1.CCOC(OCC)OCC>>CC(C)(C)c1nc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c2nncn12,,CN1CCCC1=O,,,,test
US20160175289A1,C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(NC3CNC3)cc2F)N1CC(F)(F)CO.FCCCI>>C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(NC3CN(CCCF)C3)cc2F)N1CC(F)(F)CO,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20040162314A1,NN.O=C(c1ccc(Cl)cc1)c1ccc(Cl)cc1>>NN=C(c1ccc(Cl)cc1)c1ccc(Cl)cc1,,CCO,,O,,test
US04602032,CCC[C@H]1c2cc(C)cc3c2[C@@H](Cc2ccc(OC)c(OC)c2-3)N1CC>>CCC[C@H]1c2cc(C)cc3c2[C@@H](Cc2ccc(O)c(O)c2-3)N1CC,,CO,,Cl,,test
US20090012093A1,CC(C)CCNc1nc(C(C)C)cs1.COC(=O)CCc1ccc(OCc2ccc(CCl)cc2)cc1>>COC(=O)CCc1ccc(OCc2ccc(CN(CCC(C)C)c3nc(C(C)C)cs3)cc2)cc1,,CN(C)C=O,O,Cl,[H-].[Na+],test
US05952354,NCCCCCCO.O=C(Oc1ccc([N+](=O)[O-])cc1)OC1CCN(C(=O)OCc2ccccc2)CC1>>O=C(NCCCCCCO)OC1CCN(C(=O)OCc2ccccc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20090253669A1,COC(=O)NC1(c2ccncc2)CCN(Cc2ccccc2)CC1>>NC1(c2ccncc2)CCN(Cc2ccccc2)CC1,,CO,,[K+].[OH-],,test
US20090130097A1,C#CC[C@@H](NC(=O)OC(C)(C)C)c1nc2cccnc2c(=O)n1Nc1ccccc1>>C#CC[C@@H](N)c1nc2cccnc2c(=O)n1Nc1ccccc1,,CO,,Cl,,test
US20160229815A1,O=CNCCc1ccccc1>>CNCCc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US03957850,CC(C(=O)[O-])c1ccc(N)cc1.CC(C)Br.CCO>>COC(=O)C(C)c1ccc(NC(C)C)cc1,,CCO,,c1ccncc1,,test
US20080318960A1,NNC(=O)C(NC(=O)c1ccccc1)c1n[nH]c(=O)c2ccccc12.O=Cc1ccccc1O>>O=C(NC(C(=O)N/N=C/c1ccccc1O)c1n[nH]c(=O)c2ccccc12)c1ccccc1,,CCO,,CC(=O)O,,test
US20030220524A1,CI.Sc1ccccc1Cl>>CSc1ccccc1Cl,,CO,,O,[Na],test
US05580883,CC(=O)N1CCC(Oc2ccc(N)cc2)CC1.ClCCOCCCl>>CC(=O)N1CCC(Oc2ccc(N3CCOCC3)cc2)CC1,,CN(C)C=O,,[I-].[K+],,test
US04152511,COC(=O)c1ccc(O)cc1.COCCO.ClCc1c(Br)c(Br)c(CCl)c(Br)c1Br.[O-]c1ccccc1>>COC(=O)c1ccc(OCc2c(Br)c(Br)c(COc3ccc(C(=O)OC)cc3)c(Br)c2Br)cc1,,O,,[Na+].[OH-],,test
US05597823,CCOC(=O)CS.N#Cc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]>>COC(=O)c1sc2cc([N+](=O)[O-])ccc2c1N,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20120115850A1,CC(C)(C)OC(=O)N1CCNCC1.O=[N+]([O-])c1ccc(F)cc1NCc1cccc(Br)c1>>CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)[O-])c(NCc3cccc(Br)c3)c2)CC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20130150340A1,CC(C)C1CN(C(=O)c2cc(-c3ccc(O)cc3F)nc3c2cnn3C2CCCCO2)C(C)(C)CN1C(=O)OC(C)(C)C>>CC(C)C1CN(C(=O)c2cc(-c3ccc(O)cc3F)nc3[nH]ncc23)C(C)(C)CN1,,C1CCOC1,,Cl,,test
US20080045528A1,O=C(O)c1cc(Oc2ccc3nc(NCC4CCCCC4)oc3c2)ccn1>>OCc1cc(Oc2ccc3nc(NCC4CCCCC4)oc3c2)ccn1,,C1CCOC1,,,,test
US20080027077A1,CCOC(=O)CCc1ccc(-c2cc(NCC(=O)OC(C)(C)C)ccn2)cc1>>CCOC(=O)CCc1ccc(-c2cc(NC)ccn2)cc1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20140023611A1,CC(C)(C)OC(=O)CCSCc1cccc(C(=O)O)c1.CCCN(CCC)c1ccc(N)c(-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1>>CCCN(CCC)c1ccc(NC(=O)c2cccc(CSCCC(=O)OC(C)(C)C)c2)c(-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20080096877A1,CC(C)N(c1cccc2cc(C(N)=O)[nH]c12)S(=O)(=O)c1cccs1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)N(c1cccc2cc(C(N)=S)[nH]c12)S(=O)(=O)c1cccs1,,C1CCOC1,,,,test
US20070124152A1,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(-c2ccc(F)cc2)c1=O.COCCN>>COCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(-c2ccc(F)cc2)c1=O,,CCO,,,,test
US20140163002A1,C=C[Mg]Br.O=Cc1c(C(F)(F)F)ccc(Cl)c1F>>C=CC(O)c1c(C(F)(F)F)ccc(Cl)c1F,,C1CCOC1,,,,test
US20020193361A1,C=CC[C@H](C)[C@H](OC(=O)OCC(Cl)(Cl)Cl)[C@@H](C)C(=O)C(C)(C)C(OC(C)C)OC(C)C>>C=CC[C@H](C)[C@H](OC(=O)OCC(Cl)(Cl)Cl)[C@@H](C)C(=O)C(C)(C)C=O,,C1CCOC1,O,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20120053173A1,CO.COC(=O)c1oc2ccc(F)cc2c1CBr>>COCc1c(C(=O)OC)oc2ccc(F)cc12,,CO,,Cl,C[O-].[Na+],test
US20150148340A1,CCOC(=O)c1cn(-c2ccc3c(c2)NC(=O)C3(C)C)c(=O)[nH]c1=O.FC(F)(F)c1cccc(CBr)c1Cl>>CCOC(=O)c1cn(-c2ccc3c(c2)NC(=O)C3(C)C)c(=O)n(Cc2cccc(C(F)(F)F)c2Cl)c1=O,,CN(C)C=O,O,[I-].[K+],,test
US20080039459A1,CC(=O)Nc1cccc(C2(I)Cc3nc(Cl)nc(N4CCOCC4)c3S2)c1.CI>>CC(=O)N(C)c1cccc(C2(I)Cc3nc(Cl)nc(N4CCOCC4)c3S2)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05116862,C=CCCC(CO)(CO)CO.CC(C)=O>>C=CCCC1(CO)COC(C)(C)OC1,,CC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040192914A1,c1ccc(COc2ccccc2-c2c[nH]nn2)cc1>>Oc1ccccc1-c1c[nH]nn1,[Pd],CCOC(C)=O,,CO,[H][H],test
US20050250836A1,CCOC(=O)c1ccc(C=O)[nH]1.COCCCBr>>CCOC(=O)c1ccc(C=O)n1CCCOC,,CN(C)C=O,,C1CCOC1,[H-].[Na+],test
US20090281092A1,CC(C)=O.COc1cc(C(=O)NC2CNC2)c(F)cc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C>>COc1cc(C(=O)NC2CN(C(C)C)C2)c(F)cc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C,,CC(=O)O,,CO,ClCCl,test
US20050171109A1,CCOC(=O)CCC(C)(C)c1cccc(OC)c1.O=S(=O)(c1ccccc1)N1OC1c1ccccc1>>CCOC(=O)C(O)CC(C)(C)c1cccc(OC)c1,,C1CCOC1,Cc1ccccc1,[Cl-].[NH4+],,test
US09428503B2,O=C(O)c1cnc2ccc(Br)cc2c1NC1CCOCC1.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>O=c1[nH]c2cnc3ccc(Br)cc3c2n1C1CCOCC1,,CN(C)C=O,,CCN(CC)CC,,test
US20040248854A1,COC(=O)CCCC#CCN1C(=O)CCC[C@@H]1CO>>COC(=O)CCCCCCN1C(=O)CCC[C@@H]1CO,[Pd],CO,,[H][H],,test
US20060252935A1,CC(C)(C)Cl.PC12CC3CC(CC(C3)C1)C2>>CC(C)(C)PC12CC3CC(CC(C3)C1)C2,,C1CCOC1,,[Li]CCCC,,test
US06114390,NC(=O)NC(=O)N[N+](=O)[O-].NCc1ccc(CNC(=O)[C@@H](CCCNC(N)=N[N+](=O)[O-])NC(=O)C(c2ccccc2)c2ccccc2)cc1>>NC(=O)NC(=O)NCc1ccc(CNC(=O)[C@@H](CCCNC(N)=N[N+](=O)[O-])NC(=O)C(c2ccccc2)c2ccccc2)cc1,,CO,,CCN(C(C)C)C(C)C,,test
US04515975,COC(OC)C1(C)CC(=O)c2c(C)c(O)c(C)c(C)c2O1>>COC(OC)C1(C)CCc2c(C)c(O)c(C)c(C)c2O1,,CO,,Cl,[Na+].[OH-],test
US20070099925A1,CO.Fc1ccc(-c2cn3cc(Br)ncc3n2)cc1>>COc1cn2cc(-c3ccc(F)cc3)nc2cn1,,O,,[Na+].[OH-],,test
US04631343,CCOC(=O)c1cnn(-c2ccc(Br)cc2)c1C#N>>N#Cc1c(C(=O)O)cnn1-c1ccc(Br)cc1,,CCO,,[K+].[OH-],,test
US20100048940A1,CC(C)C=O.OCC(O)CO>>CC(C)C=O.OCC(O)CO,[Pd],,,,,test
US05900486,CC(=O)N1CCN(c2ccc(OC[C@@H]3CO[C@@](Cn4ccnc4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1.CC(=O)Oc1ccc(CBr)cc1>>CC(=O)Oc1ccc(C[n+]2ccn(C[C@]3(c4ccc(Cl)cc4Cl)OC[C@H](COc4ccc(N5CCN(C(C)=O)CC5)cc4)O3)c2)cc1.[Br-],,ClC(Cl)Cl,,,,test
US20120232076A1,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.O=C(N[C@H]1CCCC[C@@H]1O)c1cc(Cc2ccc(Br)cn2)c2ccccn2c1=O>>Cn1cc(-c2ccc(Cc3cc(C(=O)N[C@H]4CCCC[C@@H]4O)c(=O)n4ccccc34)nc2)cn1,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130079306A1,COc1cc(Cl)ccc1-c1nc(C)c(C(=O)O)s1.OCc1ccc2c(c1)nc1n2CCCC1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COc1cc(Cl)ccc1-c1nc(C)c(NC(=O)OCc2ccc3c(c2)nc2n3CCCC2)s1,,Cc1ccccc1,ClC(Cl)Cl,CCN(CC)CC,,test
US20080139605A1,CN1CCCC(=O)C1.Cn1cc([N+](=O)[O-])cc([N+](=O)[O-])c1=O>>CN1CCc2cc([N+](=O)[O-])cnc2C1,,CO,,N,,test
US20020087004A1,COC(CC#N)OC.NC=CC(=O)C(F)(F)F>>N#CC=CC=CC(=O)C(F)(F)F,,COCCOC,,Cl,CC(C)(C)[O-].[K+],test
US05037824,Cc1nc(-c2ccccc2)cc(-c2cccc(C#N)c2)c1C(=O)O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cc1nc(-c2ccccc2)cc(-c2cccc(C#N)c2)c1N,,CC(C)(C)O,,CCN(CC)CC,,test
US20120142700A1,CC(C(=O)O)c1ccccc1.Cc1ccc(C)c(CC(=O)N2CCC(c3nc(N)cs3)CC2)c1>>Cc1ccc(C)c(CC(=O)N2CCC(c3nc(NC(=O)C(C)c4ccccc4)cs3)CC2)c1,,CC#N,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20130203776A1,COc1ncc(F)cc1[C@H]1CCCN1c1ccn2ncc(C(=O)O)c2n1.NCC(O)CO>>COc1ncc(F)cc1[C@H]1CCCN1c1ccn2ncc(C(=O)NCC(O)CO)c2n1,,CN(C)C=O,CS(C)=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030186872A1,C=CCN1C[C@@H](C)N([C@H](c2ccc(S(=O)(=O)N(C)C)cc2)c2cccc(O[Si](C)(C)C(C)(C)C)c2)C[C@@H]1C>>C=CCN1C[C@@H](C)N([C@H](c2ccc(S(=O)(=O)N(C)C)cc2)c2cccc(O)c2)C[C@@H]1C,,C1CCOC1,,Cl,O,test
US20090181964A1,COc1c(C(=O)O)cccc1S(=O)(=O)Cl.O=S(Cl)Cl>>COc1c(C(=O)Cl)cccc1S(=O)(=O)Cl,CN(C)C=O,,,,,test
US04242344,Clc1cn2ccnc2cn1.FC(F)(F)SCl>>FC(F)(F)Sc1cnc2cnc(Cl)cn12,,CC#N,,CCN(CC)CC,,test
US20140045862A1,COc1ccc(CN(c2nncs2)S(=O)(=O)c2cc(Cl)c(O[C@H]3CC(F)(F)CC[C@@H]3c3ccnn3C)cc2F)c(OC)c1>>Cn1nccc1[C@H]1CCC(F)(F)C[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2nncs2)cc1Cl,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US06018046,ClCc1cccnc1.O=c1ccn2c3ccc(Br)cc3c3cc(O)cc1c32>>O=c1ccn2c3ccc(Br)cc3c3cc(OCc4cccnc4)cc1c32,,CS(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20070185175A1,Nc1nc2ccc(CO)cc2s1>>Nc1nc2ccc(C=O)cc2s1,O=[Mn]=O,C1CCOC1,,,,test
US20080146631A1,CCC=Cc1ccc(OCc2ccccc2)cc1O.Cc1ccc(S(=O)(=O)OCCc2nc(-c3ccccc3)oc2C)cc1>>CCC=Cc1ccc(OCc2ccccc2)cc1OCCc1nc(-c2ccccc2)oc1C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04213984,C1CN(CCN2CCOCC2)CCN1.O=C1Nc2cccnc2N(C(=O)CCl)c2ccccc21>>O=C1Nc2cccnc2N(C(=O)CN2CCN(CCN3CCOCC3)CC2)c2ccccc21,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20090048343A1,COS(=O)(=O)OC.O=C(O)C(O)=Cc1cccc([N+](=O)[O-])c1>>COC(=O)C(=Cc1cccc([N+](=O)[O-])c1)OC,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140336190A1,COC(OC)(OC)OC.Cc1n[nH]c(C)c1-c1cc(-c2c(C)noc2C)cc(N)c1N>>COc1nc2c(-c3c(C)n[nH]c3C)cc(-c3c(C)noc3C)cc2[nH]1,,CC(=O)O,,,,test
US20090274632A1,CCOc1ccc(CNCc2ccco2)cc1.N#Cc1ccc(S(=O)(=O)Cl)cc1>>CCOc1ccc(CN(Cc2ccco2)S(=O)(=O)c2ccc(C#N)cc2)cc1,,ClCCl,O,CCN(CC)CC,,test
US20110224304A1,CO.O=C(O)C(O)c1ccccc1Br>>COC(=O)C(O)c1ccccc1Br,,CO,Cc1ccccc1,C[Si](C)(C)C=[N+]=[N-],,test
US20060100262A1,COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccccc3C=NO)n(CC3OCCO3)c2c1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccccc3CN)n(CC3OCCO3)c2c1,O=[Pt]=O,CC(=O)O,,,,test
US20060014777A1,CCOC(=O)c1ccccc1/C=C/C(=O)OCc1ccccc1.COCN(Cc1ccccc1)C[Si](C)(C)C>>CCOC(=O)c1ccccc1[C@@H]1CN(Cc2ccccc2)C[C@H]1C(=O)OCc1ccccc1,O=C(O)C(F)(F)F,ClCCl,,,,test
US04002647,CCC1(C)OC1CCC(C)=CCOc1ccc2c(c1)OCC2>>CCC1(C)OC1CCC(C)CCOc1ccc2c(c1)OCC2,O=[Pt],CCOC(C)=O,,[H][H],,test
US08889732B2,COC(=O)c1ccc(C(=O)N(Cc2ccccc2)C(=O)NCCO)s1.NN>>NNC(=O)c1ccc(C(=O)NCc2ccc(C(=O)NCCO)cc2)s1,,CCO,,O,,test
US20100016315A1,Cc1cc(F)cc(CBr)c1.NC(=O)c1cc(Cl)cnc1N>>Br.Cc1cc(F)cc(Cn2cc(Cl)cc(C(N)=O)c2=N)c1,,CN(C)C=O,,CCOC(C)=O,,test
US20150080412A1,CCn1c(CCCc2ccc(-c3ncc(OC)c(COC(C)=O)n3)cc2)nn(Cc2ccc(C(C)(C)C)cc2)c1=O>>CCn1c(CCCc2ccc(-c3ncc(OC)c(CO)n3)cc2)nn(Cc2ccc(C(C)(C)C)cc2)c1=O,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20100029633A1,COCCOc1ccnc(N)c1.O=CCCl>>COCCOc1ccn2ccnc2c1,,C1CCOC1,,,,test
US20070015773A1,BrBr.CCOC(=O)CC(=O)CC.Nc1ccccn1>>CCc1nc2ccccn2c(=O)c1Br,,O,,CC(=O)O,,test
US20060160851A1,O=C(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)N1CCC(O)CC1.Oc1ccc(N2CCN(C3CCCC3)CC2)cc1>>O=C(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)N1CCC(Oc2ccc(N3CCN(C4CCCC4)CC3)cc2)CC1,,CCOC(C)=O,,,,test
US05980780,CCCCCCCCCBr.O=C(O)c1ccc(O)cc1>>CCCCCCCCCOc1ccc(C(=O)O)cc1,,CCO,O,Cl,[K+].[OH-],test
US20090270460A1,C=CCc1ccc(OC)cc1C(=O)OC>>CCCc1ccc(OC)cc1C(=O)OC,[Pd],CO,,,,test
US20150274704A1,Cn1cc(Nc2ncc(Cl)c(NC3CC4CN(C(=O)C(F)(F)F)CC4C3)n2)cn1>>Cn1cc(Nc2ncc(Cl)c(NC3CC4CN(CC(F)(F)F)CC4C3)n2)cn1,,C1CCOC1,,B,CSC,test
US20080020989A1,CC(C)OC(=O)OC1C(O)C(CO)OC1n1c(=O)sc2cnc(N=CN(C)C)nc21>>CC(C)OC(=O)OC1C(O)C(CO)OC1n1c(=O)sc2cnc(N)nc21,,CO,,CC(=O)O,,test
US20120142640A1,Cc1ccc(CC(C#Cc2ccc(CNCCC(=O)OC(C)(C)C)cc2)c2cccc(Cl)c2)cc1C>>Cc1ccc(CC(C#Cc2ccc(CNCCC(=O)O)cc2)c2cccc(Cl)c2)cc1C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050075342A1,CCOC(=O)CCCc1c(CO)nn2c(CC)ccc2c1-c1cncc(Br)c1.O=C1NCCO1>>CCOC(=O)CCCc1c(CN2CCOC2=O)nn2c(CC)ccc2c1-c1cncc(Br)c1,,CCCCCC,Cc1ccccc1,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20020177606A1,COC(=O)C1CN(CCSc2cccs2)CCC1CCC(O)c1c(F)cnc2ccc(OC)cc12>>COc1ccc2ncc(F)c(C(O)CCC3CCN(CCSc4cccs4)CC3C(=O)O)c2c1,,CCOCC,O,C1COCCO1,[Na+].[OH-],test
US20030100772A1,CCOC(=O)c1ccc(C#CC2(c3ccc(OC)c4c3OCCO4)CCC(=O)CC2)cc1>>COc1ccc(C2(C#Cc3ccc(C(=O)O)cc3)CCC(=O)CC2)c2c1OCCO2,,CCO,,[Na+].[OH-],,test
US20120035134A1,N#CCc1ccccc1Br.OB(O)c1ccc(Cl)cc1>>N#CCc1ccccc1-c1ccc(Cl)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20100210628A1,CCOC(=O)C1CCN(c2nc(Cl)nc(Cl)n2)CC1.CN>>CCOC(=O)C1CCN(c2nc(Cl)nc(NC)n2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20030050477A1,BrBr.Cn1nc(-c2cc(N)c(Cl)cc2Cl)c(Br)c1OC(F)F>>Cn1nc(-c2c(Cl)cc(Cl)c(N)c2Br)c(Br)c1OC(F)F,,ClCCl,,CO,O,test
US20160081334A1,CCc1cc(C#C[Si](C)(C)C)cc(C)c1C1=C(OC)CC(CCNC(=O)c2ccccn2)C1=O>>C#Cc1cc(C)c(C2=C(OC)CC(CCNC(=O)c3ccccn3)C2=O)c(CC)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110224304A1,CCOC(=O)C(F)c1ccccc1Br.OB(O)c1cccc(Cl)c1>>O=C(O)C(F)c1ccccc1-c1cccc(Cl)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US20040254198A1,CC(C)N=C=S.CCOC(=O)C(=O)CBr.CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)c1csc(NC(C)C)c1C(=O)OCC,,C1CCOC1,,O,,test
US20160122356A1,CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@H]1O[C@@](C#N)(c2ccc3c(N)ncnn23)[C@@H]2OC(C)(C)O[C@@H]21)Oc1ccccc1>>CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@H]1O[C@@](C#N)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O)Oc1ccccc1,,O=CO,,,,test
US04510141,Cc1cccc(N)c1C.O=[N+]([O-])c1ccccc1F>>Cc1cccc(Nc2ccccc2[N+](=O)[O-])c1C,,CS(C)=O,,,,test
US20070010670A1,O=C(Cl)c1cc(Cl)c(O)c(Cl)c1O.c1ccc2c(c1)NCCO2>>O=C(c1cc(Cl)c(O)c(Cl)c1O)N1CCOc2ccccc21,,CCOC(C)=O,,,,test
US20090197959A1,Cc1cc(C(C)(C)O)ccc1Br.O=C1CCC(=O)N1Br>>CC(C)(O)c1ccc(Br)c(CBr)c1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20030097000A1,CCC(=O)c1ccccc1.COc1cccc(C=O)c1N>>COc1cccc2cc(C)c(-c3ccccc3)nc12,,CCO,,[K+].[OH-],,test
US20120040949A1,C=O.CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2>>CN1C[C@@H]2C[C@H]1CN2C(=O)OC(C)(C)C,,CO,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20040092546A1,C[C@H](NC(=O)c1ccc(C(=O)c2cccnc2Cl)[nH]1)c1ccccc1.NN>>C[C@H](NC(=O)c1ccc(-c2n[nH]c3ncccc23)[nH]1)c1ccccc1,,CCO,,O,,test
US20110130415A1,O=[N+]([O-])c1cc([N+](=O)[O-])c(C2CC2)c(C(F)(F)F)c1>>Nc1cc([N+](=O)[O-])c(C2CC2)c(C(F)(F)F)c1,,CO,O,CCOC(C)=O,O=C([O-])O.[Na+],test
US20100210633A1,CC(C)(C)OC(=O)N1CCC(C)(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1.O=C(O)C(F)(F)F>>CC1(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CCNCC1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20080262042A1,CCC(O)c1cccnc1F>>CCC(=O)c1cccnc1F,,O,,CCN(CC)CC,CS(C)=O,test
US20030158164A1,CC(C)(C)[Si](C)(C)O[C@H]1CC[C@H]2[C@H]3[C@H](CC[C@]12C)[C@@]1(C)CCC(=O)C[C@@H]1C[C@H]3CC=Cc1cc(OCc2ccccc2)cc(OCc2ccccc2)c1>>CC(C)(C)[Si](C)(C)O[C@H]1CC[C@H]2[C@H]3[C@H](CC[C@]12C)[C@@]1(C)CCC(=O)C[C@@H]1C[C@H]3CCCc1cc(O)cc(O)c1,[Pd],CCOC(C)=O,,,,test
US20090023801A1,COC(=O)C(N)C(c1ccccc1)C(F)(F)F.O=S(=O)(Cl)c1ccc(Cl)s1>>COC(=O)C(NS(=O)(=O)c1ccc(Cl)s1)C(c1ccccc1)C(F)(F)F,,ClCCl,ClCCl,c1ccncc1,,test
US20070197551A1,Cc1c(C(=O)O)sc2nc(SCCCN3CCN(c4ccccn4)CC3)[nH]c(=O)c12.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cc1c(N)sc2nc(SCCCN3CCN(c4ccccn4)CC3)[nH]c(=O)c12,,CC(C)(C)O,,CCN(CC)CC,,test
US20100137308A1,CCOP(OCC)OCC.COc1ccc(CBr)c([N+](=O)[O-])c1>>CCOP(=O)(Cc1ccc(OC)cc1[N+](=O)[O-])OCC,,C1CCCCC1,CCOC(C)=O,,,test
US03939273,ClCC=Cc1ccccc1.Oc1ccc2c(c1)OCO2>>C(=Cc1ccccc1)COc1ccc2c(c1)OCO2,,CC(C)=O,,[I-].[K+],,test
US20130129753A1,COC1=N[C@H](C(C)C)C(OC)=N[C@H]1Cc1ccc2ncccc2c1.O=C(O)C(F)(F)F>>COC(=O)[C@@H](N)Cc1ccc2ncccc2c1,,CC#N,O,,,test
US20110312936A1,CC(C)[Mg]Br.O=CC1CCC2(CC1)OCCO2>>CC(C)C(O)C1CCC2(CC1)OCCO2,,C1CCOC1,,,,test
US20070142672A1,C=C[C@H](C)[C@@H](NNC(=O)c1ccccc1)C(=O)OCC>>CCOC(=O)[C@H](NNC(=O)c1ccccc1)[C@@H](C)CC,[Pd],CCO,,,,test
US20070249665A1,Cc1nc(Cl)c2ccccc2c1C=O.O=S(Cl)Cl>>Cc1nc(Cl)c2ccccc2c1CCl,,C1CCOC1,ClCCl,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100280001A1,CC(C)(C)[Si](C)(C)OCCCNc1c(N)cnc2ccccc12.CCCCC(=O)Cl.CN1CCCC1=O>>CCCCC(=O)OCCCn1c(CCCC)nc2cnc3ccccc3c21,,CN1CCCC1=O,,,,test
US20040192686A1,CN(C)CCN.COc1ccc2nc(Cl)n[n+]([O-])c2c1>>COc1ccc2nc(NCCN(C)C)n[n+]([O-])c2c1,,COCCOC,,,,test
US20140323501A1,CC(C)C(=O)O.CCOC(=O)C(CC(=O)c1ccc(Oc2ccc(C(=O)CCl)cc2)cc1)(NC(C)=O)C(=O)OCC>>CCOC(=O)C(CC(=O)c1ccc(Oc2ccc(C(=O)COC(=O)C(C)C)cc2)cc1)(NC(C)=O)C(=O)OCC,,CC#N,,CCN(CC)CC,,test
US20140155381A1,Br[Mg]c1ccccc1.Cc1cnccc1C#N>>Cc1cnccc1C(N)c1ccccc1,,C1CCOC1,,[BH4-].[Na+],,test
US20070213549A1,C=COC(C)=O.C=C[Si](CC)(CC)CC.CC[SiH](CC)CC>>CC[Si](CC)(CC)CC.CC[Si](O)(CC)CC,,Cc1ccccc1,,,,test
US20050124692A1,COc1cc(CC(O)CO)c(OCc2ccccc2)c2c1C1CCC2CC1.Cc1ccc(S(=O)(=O)OCC2Cc3cc(C)c4c(c3O2)CCC4)cc1>>COc1cc(CC(O)COS(=O)(=O)c2ccc(C)cc2)c(OCc2ccccc2)c2c1C1CCC2CC1,,c1ccncc1,,Cc1ccc(S(=O)(=O)Cl)cc1,,test
US20120178751A1,O=[N+]([O-])c1cc(-c2cn3cc(Cl)ncc3n2)ccc1C(F)(F)F>>Nc1cc(-c2cn3cc(Cl)ncc3n2)ccc1C(F)(F)F,[Fe],CCO,O,CC(=O)O,,test
US20070066618A1,CO.O=[N+]([O-])c1cc(CCl)c(Cl)cc1Cl>>COCc1cc([N+](=O)[O-])c(Cl)cc1Cl,,CO,,C[O-].[Na+],,test
US20020099212A1,CC(=O)N(Cc1ccc(Cl)cc1Cl)c1cc(C(N)=O)ccc1C(N)=O>>Cc1nc(=O)c2ccc(C(N)=O)cc2n1Cc1ccc(Cl)cc1Cl,,CO,,Cl,,test
US20070049618A1,Cc1cccc(C(=O)Cl)c1.NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O>>Cc1cccc(C(=O)NCc2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)c1,,C1CCOC1,,CCN(CC)CC,Cl,test
US20100112090A1,CCOC(=O)CBr.O=C1c2ccccc2C(=O)N1c1cc(S(=O)(=O)N2CCCCc3ccccc32)c(O)cc1Cl>>CCOC(=O)COc1cc(Cl)c(N2C(=O)c3ccccc3C2=O)cc1S(=O)(=O)N1CCCCc2ccccc21,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20110305729A1,CCOC(=O)CCCCCCN(c1ccccn1)c1cc(OCc2ccccc2)ccn1.NO>>O=C(CCCCCCN(c1ccccn1)c1cc(OCc2ccccc2)ccn1)NO,,CN(C)C=O,CO,,,test
US20150011546A1,COC(=O)c1c(C)n(C(C)c2ccccc2)c2cccnc12>>Cc1c(C(=O)O)c2ncccc2n1C(C)c1ccccc1,,CO,O,Cl,[Li+].[OH-],test
US20090270393A1,Cl.N#CC(C(N)=O)C1OC(=O)C(Cl)=C1Cl.NCc1ccccc1S(=O)(=O)c1ccccc1>>Cl.N=c1c(C(N)=O)cc(Cl)cn1Cc1ccccc1S(=O)(=O)c1ccccc1,,CCO,,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20010005757A1,CC(=O)O[C@H]1CC[C@]2(C)C3=C(C[C@H](O)[C@H]2C1)[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC3>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](O)C[C@H]1[C@H](O)C3,,CCO,,[K],,test
US20090275602A1,CC(C)(C)OC(=O)N[C@@H](Cc1cccc(C#C[Si](C)(C)C)c1)[C@@H](CO)O[Si](C)(C)C(C)(C)C>>CC(C)(C)OC(=O)N[C@@H](Cc1cccc(C#C[Si](C)(C)C)c1)[C@@H](C=O)O[Si](C)(C)C(C)(C)C,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US20060264460A1,N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1.O=Cc1cc2ccccc2[nH]1>>N#Cc1cnc2ccc(NCc3cc4ccccc4[nH]3)cc2c1Nc1ccc(F)c(Cl)c1,,CCO,,[BH3-]C#N.[Na+],,test
US20130018034A1,CCOC(=O)c1ccc(F)cc1.OC1CNC1>>CCOC(=O)c1ccc(N2CC(O)C2)cc1,,CCOC(C)=O,CS(C)=O,Cl,O=C([O-])[O-].[K+].[K+],test
US04514416,CCOCC.CS(=O)(=O)Oc1ccc(C(=N)N)cc1Cl.O=C(Cl)c1ccccc1>>CS(=O)(=O)O.N=C(N)c1ccc(OC(=O)c2ccccc2)c(Cl)c1,,CCOCC,,c1ccncc1,,test
US20140094453A1,NC1=NS(=O)(=O)Nc2cccc(OC[C@H]3CCCC[NH2+]3)c21.O=C(Nc1ccncc1)Oc1ccc([N+](=O)[O-])cc1>>NC1=NS(=O)(=O)Nc2cccc(OC[C@H]3CCCCN3C(=O)Nc3ccncc3)c21,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US05032598,CN1CCC(C2(C(N)=O)Cc3ccc([N+](=O)[O-])cc3C2=O)CC1>>CN1CCC(C2Cc3ccc([N+](=O)[O-])cc3C2=O)CC1,,Cl,,[Na+].[OH-],,test
US20100210619A1,CCCN(CC1CC1)c1cc(C(=O)Nc2ccc3[nH]ncc3c2)ncn1.CCOC(=O)CBr>>CCCN(CC1CC1)c1cc(C(=O)Nc2ccc3c(cnn3CC(=O)OCC)c2)ncn1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090118500A1,COC(=O)c1ccc(C(=O)NCc2cccnc2)s1.NN>>NNC(=O)c1ccc(C(=O)NCc2cccnc2)s1,,CCO,,O,,test
US05607956,CC(=O)c1cccs1.Cc1ncsc1C>>Cc1nc(C(C)(O)c2cccs2)sc1C,,CCOCC,,[Li]CCCC,,test
US20080176862A1,CN1C(=O)C(c2ccc(OS(C)(=O)=O)cc2)(c2cncc(Br)c2)N=C1N.COc1ccc(F)c(B(O)O)c1>>COc1ccc(F)c(-c2cncc(C3(c4ccc(OS(C)(=O)=O)cc4)N=C(N)N(C)C3=O)c2)c1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20140336190A1,C=C(c1ccccc1)c1cc(-c2c(C)noc2C)cc2[nH]c(C3CC3)nc12>>Cc1noc(C)c1-c1cc(C(C)c2ccccc2)c2nc(C3CC3)[nH]c2c1,[Pd],CCO,,,,test
US05773448,ClCCBr.O=C1Nc2ccc(F)cc2C1=O>>O=C1C(=O)N(CCCl)c2ccc(F)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20140194403A1,Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12.O=C(n1ccnc1)n1ccnc1.OC1CNC1>>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3Cl)nc12)N1CC(O)C1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20100216802A1,CC(C)(C)OC(=O)N[C@@H](CC1CCNCC1)C(=O)OC1CCCC1.O=CCNC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](CC1CCN(CCNC(=O)OCc2ccccc2)CC1)C(=O)OC1CCCC1,,ClCCCl,,,,test
US20040116689A1,COC(=O)CN(CCNC(c1ccccc1)(c1ccccc1)c1ccc(OC)cc1)C(=O)Cc1n[nH]c2ncnc(NC(=O)c3ccc(OC)cc3)c12>>COc1ccc(C(=O)Nc2ncnc3[nH]nc(CC(=O)N(CCNC(c4ccccc4)(c4ccccc4)c4ccc(OC)cc4)CC(=O)O)c23)cc1,,C1COCCO1,,[Na+].[OH-],,test
US06538152B1,BrCc1ccccc1.CCOC(=O)COc1ccc(CCBr)cc1O>>CCOC(=O)COc1ccc(CCBr)cc1OCc1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080319005A1,COc1ccc(B(O)O)cc1.Nc1cc(Br)cc(C(F)(F)F)c1>>COc1ccc(-c2cc(N)cc(C(F)(F)F)c2)cc1,,CCCCCC,CCOC(C)=O,,,test
US20100249119A1,CN(c1cccc(NC(=O)c2cccc(C(F)(F)F)c2)c1)c1ncc([N+](=O)[O-])c(SC#N)n1>>CN(c1cccc(NC(=O)c2cccc(C(F)(F)F)c2)c1)c1ncc2nc(N)sc2n1,,CC(=O)O,,,,test
US04433152,Cl.N=C(N)N1CCC(C(=O)O)CC1.O=S(Oc1ccc(Cl)cc1)Oc1ccc(Cl)cc1>>Cl.N=C(N)N1CCC(C(=O)Oc2ccc(Cl)cc2)CC1,,c1ccncc1,,CN(C)C=O,,test
US20100035865A1,O=C(O)[C@@H]1CCOC[C@H]1c1ccc(-c2ccccc2)cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>N[C@@H]1CCOC[C@H]1c1ccc(-c2ccccc2)cc1,,C1CCOC1,Cc1ccccc1,CCN(C(C)C)C(C)C,[Na+].[OH-],test
US20090209523A1,CC(=O)OC(C)=O.O=C([O-])C(F)(F)F.[NH3+]CCN1CCCN(C(=O)c2cc(Cc3c[nH]c(=O)c4cc(Cl)c(Cl)n34)ccc2F)CC1>>CC(=O)NCC[NH+]1CCCN(C(=O)c2cc(Cc3c[nH]c(=O)c4cc(Cl)c(Cl)n34)ccc2F)CC1.O=C([O-])C(F)(F)F,,c1ccncc1,,,,test
US20100286112A1,CC(C)c1noc(N2CCC(CCCOc3ccc([C@H](NC(=O)OC(C)(C)C)C(=O)N4CCC[C@H]4C#N)cc3)CC2)n1>>CC(C)c1noc(N2CCC(CCCOc3ccc([C@H](N)C(=O)N4CCC[C@H]4C#N)cc3)CC2)n1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20080081822A1,CC(C)(Br)C(=O)Nc1cc(C(C)(C)C)on1.CC(C)CS>>CC(C)CSC(C)(C)C(=O)Nc1cc(C(C)(C)C)on1,,CCO,,[K+].[OH-],,test
US09145354B2,C[C@@H](CC(=O)NCCNC(=O)OC(C)(C)C)NCc1ccc(Cl)c(C(=O)c2ccccc2)c1F>>C[C@@H](CC(=O)NCCN)NCc1ccc(Cl)c(C(=O)c2ccccc2)c1F,,CCOC(C)=O,,Cl,,test
US04966835,CCCCC(CC)Cn1c(=O)cc(Cl)[nH]c1=O.CI>>CCCCC(CC)Cn1c(=O)cc(Cl)n(C)c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100137394A1,COc1cc(Cl)c(CC(=O)N2CCC(c3ccc(NC(=O)Oc4ccc([N+](=O)[O-])cc4)cc3)=N2)cc1OC.N>>COc1cc(Cl)c(CC(=O)N2CCC(c3ccc(NC(N)=O)cc3)=N2)cc1OC,,CN1CCCC1=O,O,CO,ClCCl,test
US20150191463A1,Br[Mg]C1CC1.O=Cc1ccc(Br)cc1F>>OC(c1ccc(Br)cc1F)C1CC1,,CCOCC,,C1CCOC1,,test
US20060030613A1,Fc1cc2[nH]ccc2cc1Cl.O=C=O>>O=C(O)c1c(F)c(Cl)cc2cc[nH]c12,,C1CCOC1,CCCCCC,O,[Li]CCCC,test
US20060069077A1,COC(=O)CBr.COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1O>>COC(=O)COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3)c2cc1OC,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20110257196A1,Clc1nccc2ccc(Br)cc12.OB(O)c1ccc2[nH]ccc2c1>>Clc1nccc2ccc(-c3ccc4[nH]ccc4c3)cc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040248949A1,N#CCCNC(=O)[C@@H]1CCCC[C@@H]1N.N#CCNC(=O)[C@@H]1CCCC[C@@H]1NC(=O)c1ccc(F)cc1.NCc1ccncc1.O=C(Cl)c1ccc(S(=O)(=O)F)cc1>>N#CCNC(=O)[C@@H]1CCCC[C@@H]1NC(=O)c1ccc(S(=O)(=O)NCc2ccncc2)cc1,,CO,ClCCl,CCN(CC)CC,c1ccncc1,test
US20020040146A1,BrCc1ccccc1.CC(C)(C)O[C@@H]1C[C@@H](CO)N(S(=O)(=O)c2ccc3ccccc3c2)C1>>CC(C)(C)O[C@@H]1C[C@@H](COCc2ccccc2)N(S(=O)(=O)c2ccc3ccccc3c2)C1,,CS(C)=O,,[H-].[Na+],,test
US20120046267A1,CC(C)(C)Sc1c(Br)cc([N+](=O)[O-])cc1C=O.NO>>CC(C)(C)Sc1c(Br)cc([N+](=O)[O-])cc1C=NO,,CC(C)O,O,Cl,,test
US20070244131A1,COc1ccc(CCNc2cc(-c3cccc(C(=O)N=C(C)N(C)C)c3)nc(OC)n2)cc1.NN>>COc1ccc(CCNc2cc(-c3cccc(-c4nc(C)n[nH]4)c3)nc(OC)n2)cc1,,CC(=O)O,,O,,test
US20120029026A1,CNc1cc(Oc2ccnc(OC)c2)ccc1NC(=O)COc1cccc(C(=O)OC)c1>>COC(=O)c1cccc(OCc2nc3ccc(Oc4ccnc(OC)c4)cc3n2C)c1,,CC(=O)O,,,,test
US20050222225A1,CCOC(=O)C=Cc1coc2ccc(C=C3SC(=O)NC3=O)cc12>>O=C(O)C=Cc1coc2ccc(C=C3SC(=O)NC3=O)cc12,,C1CCOC1,O,[Li]O,,test
US20050192300A1,C1COCCN1.COc1cccc(Nc2nccc(-c3sc(NC(=O)CCBr)nc3C)n2)c1>>COc1cccc(Nc2nccc(-c3sc(NC(=O)CCN4CCOCC4)nc3C)n2)c1,,CC#N,,,,test
US20130045963A1,O=Cc1cc(OC2CCC3(CC2)OCCO3)nc(C(F)(F)F)n1>>OCc1cc(OC2CCC3(CC2)OCCO3)nc(C(F)(F)F)n1,,CC(C)O,,[BH4-].[Na+],,test
US20130274258A1,Cc1ccccc1Nc1ccc(Br)cc1.OB(O)c1ccc2c(c1)CCO2>>Cc1ccccc1Nc1ccc(-c2ccc3c(c2)CCO3)cc1,,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20100240713A1,O=C(O)c1sc(C(=O)O)c(-c2ccccc2)c1-c1ccccc1>>OCc1sc(CO)c(-c2ccccc2)c1-c1ccccc1,,C1CCOC1,,CO,Cl,test
US05210092,CCCc1nc2c(C)ccnc2n1Cc1ccc(-n2cc(Cl)cc2-c2nnn[nH]2)cc1.Cl>>CCCc1nc2c(C)ccnc2n1Cc1ccc(-n2cc(Cl)cc2-c2nnn[nH]2)cc1.Cl,,CCO,,,,test
US04559345,CCOC(=O)CNc1nc(Cl)cc(Nc2cccc(C)c2C)n1>>Cc1cccc(Nc2cc(Cl)nc(NCC(=O)O)n2)c1C,,CCO,O,[Na+].[OH-],,test
US20100022613A1,Fc1ccc(CBr)cc1.Sc1cccc(Br)c1>>Fc1ccc(CSc2cccc(Br)c2)cc1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140235622A1,Cn1ncc(Br)c1-c1cc(N)ccc1ON(C(=O)OC(C)(C)C)C(C)(C)C.O=C(Cl)c1ccc(F)cc1>>Cn1ncc(Br)c1-c1cc(NC(=O)c2ccc(F)cc2)ccc1OCC(C)(C)N,,ClCCl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20010031763A1,COc1ccc2nc3cc(Cl)ccc3c(NCCNc3c4ccc(Cl)cc4nc4ccc(OC)cc34)c2c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccc2nc3cc(Cl)ccc3c(NCCN(C(=O)C(F)(F)F)c3c4ccc(Cl)cc4nc4ccc(OC)cc34)c2c1,,ClCCl,,CCN(CC)CC,,test
US20020103240A1,CCCNC1CCc2nc(N)sc2C1.Cl>>CCCNC1CCc2nc(N)sc2C1.Cl,,CO,,,,test
US20030008907A1,COS(=O)(=O)OC.COc1ccc([N+](=O)[O-])c(NC(=O)OC(C)(C)C)c1>>COc1ccc([N+](=O)[O-])c(N(C)C(=O)OC(C)(C)C)c1,,CN(C)C=O,,O,[H-].[Na+],test
US04946771,O=C(NC1=NN(c2c(Cl)cc(Cl)cc2Cl)C(=O)C1Br)c1cccc([N+](=O)[O-])c1.c1cn[nH]c1>>O=C(NC1=NN(c2c(Cl)cc(Cl)cc2Cl)C(=O)C1c1cc[nH]n1)c1cccc([N+](=O)[O-])c1,,CC#N,,,,test
US20150119380A1,CCOC(=O)CC(C)=O.O=Cc1ccc(O)cc1O>>CC(=O)c1cc2ccc(O)cc2oc1=O,,CC#N,,C1CCNCC1,CC(=O)O,test
US07060721B1,CCCCCOc1ccc(Cn2c(C)nc(Cl)c2CCl)c(Cl)c1.N>>CCCCCOc1ccc(Cn2c(C)nc(Cl)c2CN)c(Cl)c1,,CC#N,,O=C([O-])O.[Na+],,test
US20040142921A1,COC(=O)[C@@H](N)Cc1ccc(O)cc1.Cc1ccc(C(=O)C2CCCCC2=O)cc1>>COC(=O)C(Cc1ccc(O)cc1)Nc1ccccc1C(=O)c1ccc(C)cc1,[Pd],COc1ccccc1,,CO,O,test
US20150246894A1,CCOC=N.NNC(=O)CN1C(=O)OC(c2ccc(F)cc2)(c2ccc(F)cc2)[C@@H]1c1ccccc1F>>O=C1OC(c2ccc(F)cc2)(c2ccc(F)cc2)[C@H](c2ccccc2F)N1Cc1nnc[nH]1,,CCOC(C)=O,CN1CCCC1=O,Cl,,test
US20150045346A1,O=C1N[C@@H]2[C@H](F)[C@H](O)[C@@H](CO)C[C@@H]2O1>>N[C@@H]1[C@H](F)[C@H](O)[C@@H](CO)C[C@@H]1O,,CO,O,[Li+].[OH-],,test
US20040133011A1,CCCCCC12CCC(C(=O)O)(CC1)CC2.CO>>CCCCCC12CCC(C(=O)OC)(CC1)CC2,,CO,ClCCl,C[Si](C)(C)C=[N+]=[N-],,test
US04275160,CCOC(=O)CCCC1C(=O)c2ccccc2N(CCCN(C)C)c2ccccc21>>CCOC(=O)CCCC1Cc2ccccc2N(CCCN(C)C)c2ccccc21,[Pd],CC(=O)O,,,,test
US04764610,C=CC(=O)O.c1ccc2[nH]ccc2c1>>O=C(O)CCc1c[nH]c2ccccc12,,CC(=O)O,,,,test
US04539579,CCCCn1c(C)c(C2(c3c(C)n(CCCC)c4ccccc34)OC(=O)c3ccccc32)c2ccccc21.NN>>CCCCn1c(C)c(C2(c3c(C)n(CCCC)c4ccccc34)NNC(=O)c3ccccc32)c2ccccc21,,O,,CCO,,test
US20110059954A1,COc1ccc2c(c1)CCN(C1CCNCC1)C(=O)N2.Cc1cnc(Cl)cc1C(=O)c1cc(C)c2[nH]c(=O)oc2c1>>COc1ccc2c(c1)CCN(C1CCN(c3cc(C(=O)c4cc(C)c5[nH]c(=O)oc5c4)c(C)cn3)CC1)C(=O)N2,,CN(C)C=O,,,,test
US20160108027A1,C1COCCN1.COc1cc(C(=O)N2CCC[C@@]2(C)C(=O)O)cc2nc(NCc3cc(Cl)ccn3)oc12>>COc1cc(C(=O)N2CCCC2(C)C(=O)N2CCOCC2)cc2nc(NCc3cc(Cl)ccn3)oc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080039457A1,CCN.O=C(O)c1ccc(-c2cnc3nnc(C4(c5ccc6ncccc6c5)CC4)n3n2)cc1F>>CCNC(=O)c1ccc(-c2cnc3nnc(C4(c5ccc6ncccc6c5)CC4)n3n2)cc1F,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US04107201,Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>Nc1cc(N)cc(N)c1,[Pd],CCOC(C)=O,,,,test
US06395733B1,C#Cc1cccc(N)c1.O=C(O)c1c[nH]c2ncnc(Cl)c12>>C#Cc1cccc(Nc2ncnc3[nH]cc(C(=O)O)c23)c1,,CO,,,,test
US06200784B1,CCCCCCCCCCCC(=O)O.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>CCCCCCCCCCCC(=O)OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O,,CC(C)=O,,,,test
US20110152237A1,CCOC(=O)C1CC2(CCC(O[Si](C)(C)C(C)(C)C)CC2)CN1.O=C(Cl)OCc1ccccc1>>CCOC(=O)C1CC2(CCC(O[Si](C)(C)C(C)(C)C)CC2)CN1C(=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US04069382,CC(=O)Cl.Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O>>CC(=O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H](O)[C@@H]1O,,CN(C)C=O,c1ccncc1,,,test
US20080255160A1,Cn1c(=O)cc(Nc2ccc(I)cc2F)c2c(=O)[nH]cnc21.O=[N+]([O-])c1ccc(Cl)c([N+](=O)[O-])c1>>Cn1c(=O)cc(Nc2ccc(I)cc2F)c2c(=O)n(-c3ccc([N+](=O)[O-])cc3[N+](=O)[O-])cnc21,,CN(C)C=O,,[I-].[K+],,test
US20130089512A1,CCOC(=O)c1cnc(-c2cnn3cccnc23)cc1NC1CCOCC1>>O=C(O)c1cnc(-c2cnn3cccnc23)cc1NC1CCOCC1,,CCO,,[Na+].[OH-],,test
US04080455,CC(C)=CCCC(C)=CCO.O=c1[nH]c(Cl)ncc1F>>CC(C)=CCCC(C)=CCOc1ncc(F)c(=O)[nH]1,,Cc1ccccc1,,[Na],,test
US20110172442A1,CC(C)(C)OC(=O)N[C@@H](Cc1cn(Cc2ccccc2)c2ccccc12)C(=O)OCc1ccccc1.Cl>>Cl.N[C@@H](Cc1cn(Cc2ccccc2)c2ccccc12)C(=O)OCc1ccccc1,,ClCCl,,C1COCCO1,,test
US20150232435A1,NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1.O=C(n1ccnc1)n1ccnc1.c1ccc(N2CCNCC2)cc1>>O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)N1CCN(c2ccccc2)CC1,,C1CCOC1,,,,test
US20160244410A1,COc1ccc(Cn2c(=O)c3c(OS(=O)(=O)C(F)(F)F)cc(=O)n(C)c3n(-c3ccc(I)cc3F)c2=O)cc1.Cc1ccc(O)c(C)c1>>COc1ccc(Cn2c(=O)c3c(Oc4ccc(C)cc4C)cc(=O)n(C)c3n(-c3ccc(I)cc3F)c2=O)cc1,,C1CCOC1,,[H-].[Na+],,test
US20060100429A1,CC(C)(O)C#Cc1nc2c(Cl)ncnc2n1C1CCCCO1>>C#Cc1nc2c(Cl)ncnc2n1C1CCCCO1,,Cc1ccccc1,,[K+].[OH-],,test
US20110251186A1,CC(C)(C)OC(=O)NC1=N[C@]2(COC1)c1cc(OS(=O)(=O)C(F)(F)F)ccc1Oc1ccc(-c3cccnc3F)cc12.CC1(C)OB(C2=CCOCC2)OC1(C)C>>NC1=N[C@]2(COC1)c1cc(C3=CCOCC3)ccc1Oc1ccc(-c3cccnc3F)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20010021775A1,CCOC(=O)CN(C(=O)OC(C)(C)C)c1cc(C#N)ccc1N>>N#Cc1ccc2c(c1)NCC(=O)N2,,C1COCCO1,CO,CCOCC,Cl,test
US20050215577A1,COC(=O)C(F)(C1CCCC(=O)C1)S(=O)(=O)c1ccccc1.NNc1ccc(Cl)cc1>>COC(=O)C(F)(C1CCc2c([nH]c3ccc(Cl)cc23)C1)S(=O)(=O)c1ccccc1,,CC(=O)O,,Cl,O=C([O-])O.[Na+],test
US04299821,CCC[C@H](NC(=O)[C@@H]1CCC(=O)N1C(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(N)=O>>CCC[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)N1CCC[C@H]1C(N)=O,[Pd],CO,,[H][H],,test
US04405780,C#CCc1c(Cl)nc(N)nc1-c1ccccc1.NNC=O>>C#CCc1c(-c2ccccc2)nc(N)n2cnnc12,,O,,CN(C)C=O,,test
US20090247538A1,CCOC(=O)c1cnc2[nH]ncc2c1N1CCC(N)(Cc2ccc(Cl)cc2)CC1>>NC1(Cc2ccc(Cl)cc2)CCN(c2ccnc3[nH]ncc23)CC1,,[K+],[OH-],O,,test
US20140315888A1,CN1CCNCC1.Cc1nc2c3cc(Cl)cnc3nc(Cl)n2n1>>Cc1nc2c3cc(Cl)cnc3nc(N3CCN(C)CC3)n2n1,,CN(C)C=O,,,,test
US07521461B2,CCCCCCN(Cc1ccccc1)C(=O)Cc1ccc(O)c(F)c1.COC(=O)c1ccccc1CBr>>CCCCCCN(Cc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2C(=O)OC)c(F)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130109662A1,C=C1CC(=O)O1.CNCCO>>CC(=O)CC(=O)N(C)CCO,,C1CCOC1,,,,test
US20090149457A1,CCOC(=O)n1nc(NC(=O)c2ccccc2[N+](=O)[O-])c2cc(C(=O)OC(C)(C)C)sc21>>CCOC(=O)n1nc(NC(=O)c2ccccc2N)c2cc(C(=O)OC(C)(C)C)sc21,[Pd],CCOC(C)=O,,,,test
US20120053174A1,Cc1cc(Nc2nc(C(=O)c3ccc(F)cn3)nc3ccccc23)n[nH]1.OCCO>>Cc1cc(Nc2nc(C3(c4ccc(F)cn4)OCCO3)nc3ccccc23)n[nH]1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04690931,O=C(CBr)c1ccc(Cl)cc1.c1ccc(CC2CCNCC2)cc1>>O=C(CN1CCC(Cc2ccccc2)CC1)c1ccc(Cl)cc1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20050026916A1,ClCc1ccccc1.S=C1N[C@@H](c2ccccc2)[C@@H](c2ccccc2)N1>>Cl.c1ccc(CSC2=N[C@@H](c3ccccc3)[C@@H](c3ccccc3)N2)cc1,,CCO,,,,test
US20130165464A1,N.O=C(O)c1cn(-c2cc(Cl)ncc2Cl)cc1-c1ccccc1Cl>>NC(=O)c1cn(-c2cc(Cl)ncc2Cl)cc1-c1ccccc1Cl,,ClCCl,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20050256333A1,CC(=O)c1ccc(O)cc1.CN(C)C=O.CN(CCCl)Cc1ccccc1F>>CN(CCOCC(=O)c1ccccc1)Cc1ccccc1F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090318690A1,CC#CCBr.OCc1c(OCC2CC2)ccc2c(CCC3CCNCC3)noc12>>CC#CCN1CCC(CCc2noc3c(CO)c(OCC4CC4)ccc23)CC1,,O,,CCN(CC)CC,CN(C)C=O,test
US20060211689A1,CN(C)c1ccc(N)c(C(=O)O)c1.O=C(Cl)OC(Cl)(Cl)Cl>>CN(C)c1ccc2[nH]c(=O)oc(=O)c2c1,,C1COCCO1,,O,,test
US20150111887A1,CC(C)(C)OC(=O)N1CCN(c2ncc(C(CO)c3ccc(F)cc3)cn2)CC1>>OCC(c1ccc(F)cc1)c1cnc(N2CCNCC2)nc1,,C1COCCO1,,Cl,,test
US20120208817A1,CCOc1cc(C=O)cc([N+](=O)[O-])c1O.NC(N)=O.O=C(Cc1ccccc1)c1ccc2cnccc2c1>>CCOc1cc(C2NC(=O)NC(c3ccc4cnccc4c3)=C2c2ccccc2)cc([N+](=O)[O-])c1O,,CCO,,Cl,,test
US05866589,CCN(c1ncccc1[N+](=O)[O-])C1CCN(Cc2ccccc2)CC1>>CCN(c1ncccc1N)C1CCN(Cc2ccccc2)CC1,O=[Pt],CCO,,,,test
US04990531,O=C1CCCN1.O=S(=O)(Cl)c1ccc2ccccc2c1>>O=C1CCCN1S(=O)(=O)c1ccc2ccccc2c1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20090247746A1,COCn1c(C(N)=O)cc2c(F)ccc(N(C)S(=O)(=O)c3cccs3)c21.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COCn1c(C(N)=S)cc2c(F)ccc(N(C)S(=O)(=O)c3cccs3)c21,,C1CCOC1,,,,test
US20130005707A1,Brc1nc2cccc(Br)n2n1.CC1(O)CNC1>>CC1(O)CN(c2cccc3nc(Br)nn23)C1,,CS(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20050059677A1,CCOC(OCC)(OCC)c1ccc2c(-c3ccnc(NC4CCCC4)n3)c(-c3ccc(F)cc3)nn2c1Cl>>CCOC(=O)c1ccc2c(-c3ccnc(NC4CCCC4)n3)c(-c3ccc(F)cc3)nn2c1Cl,,CC(C)=O,O,Cc1ccc(S(=O)(=O)O)cc1,,test
US08076500B2,Cc1ccccc1.Nc1ccccc1.O=[N+]([O-])c1ccccc1>>O=C(Nc1ccccc1)Nc1ccccc1,,O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20060205739A1,Cc1cc(C#N)c(S)nc1C.O=C(CBr)c1cc(F)ccc1F>>Cc1cc2c(N)c(C(=O)c3cc(F)ccc3F)sc2nc1C,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20160222005A1,Cc1nnc2n1CCNC2.Nc1nc(Cl)ccc1[N+](=O)[O-]>>Cc1nnc2n1CCN(c1ccc([N+](=O)[O-])c(N)n1)C2,,O,,CCN(C(C)C)C(C)C,CN(C)C=O,test
US04064261,NNc1nc2ccccc2s1.S=C=S>>Sc1nnc2sc3ccccc3n12,,CCO,,[K+].[OH-],,test
US20160222014A1,C[Si](C)(C)C#Cc1cnc(Cl)cc1N>>Clc1cc2[nH]ccc2cn1,,CN(C)C=O,O,CC(C)(C)[O-].[K+],,test
US20060128685A1,CCOC(=O)C(=O)CC(=O)c1cccc(C)c1.COc1ccc(NN)cn1>>CCOC(=O)c1cc(-c2cccc(C)c2)n(-c2ccc(OC)nc2)n1,,CCO,,CCN(CC)CC,Cl,test
US20050014744A1,COc1ccc(N)c(S(N)(=O)=O)c1.N=CN>>COc1ccc2c(c1)S(=O)(=O)N=CN2,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US20050032786A1,CC(C)(C)OC(=O)CCCCCBr.O=c1nc(-c2ccccn2)sc2ccc(O)cc12>>CC(C)(C)OC(=O)CCCCCOc1ccc2sc(-c3ccccn3)nc(=O)c2c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140011824A1,CN(C)C=Nc1nc(O)ncc1F.O=C=NCc1ccccc1>>CN(C)/C=N/c1nc(=O)n(C(=O)NCc2ccccc2)cc1F,,ClCCl,,,,test
US05089504,CCCC(=O)c1cnc2c(C=O)cccc2c1Nc1ccccc1C.C[Mg]I>>CCCC(=O)c1cnc2c(C(C)O)cccc2c1Nc1ccccc1C,,CCOCC,ClCCl,CO,,test
US20040236114A1,C[C@H](O)[C@@H](CCOc1cccc(Br)c1)n1cnc(C(N)=O)c1.OB(O)c1cc2ccccc2s1>>C[C@H](O)[C@@H](CCOc1cccc(-c2cc3ccccc3s2)c1)n1cnc(C(N)=O)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20070185160A1,COC(OC)OC.Nc1ccc2cc(-c3ccccc3C(F)(F)F)[nH]c(=O)c2c1.[N-]=[N+]=[N-]>>O=c1[nH]c(-c2ccccc2C(F)(F)F)cc2ccc(-n3cnnn3)cc12,,O,,CC(=O)O,,test
US06083961,CCN(C(C)=O)c1cccc(OCc2ccccc2)c1[N+](=O)[O-]>>CCn1c(C)nc2c(OCc3ccccc3)cccc21,[Fe],CC(=O)O,CCO,,,test
US05064833,C1CCNC1.Cc1ccccc1Nc1nc(Cl)nc2ccccc12>>Cc1ccccc1Nc1nc(N2CCCC2)nc2ccccc12,,CCO,,,,test
US20100105740A1,COc1cc(CNC(C)=O)c(Br)cc1OC(C)=O>>COc1cc(CNC(C)=O)c(Br)cc1O,,C1COCCO1,,Cl,,test
US20110294793A1,CC(C)CNCc1cc(Cl)cc(CN(CC(C)C)S(=O)(=O)c2cc(Cl)cc(Cl)c2O)c1.O=S(=O)(Cl)c1cccnc1>>CC(C)CN(Cc1cc(Cl)cc(CN(CC(C)C)S(=O)(=O)c2cc(Cl)cc(Cl)c2O)c1)S(=O)(=O)c1cccnc1,,C1CCOC1,,CCN(CC)CC,,test
US20040006060A1,Nc1ccccc1C(O)(C(F)(F)F)C(F)(F)F.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=C1Nc2ccccc2C(C(F)(F)F)(C(F)(F)F)O1,,C1CCOC1,,,,test
US20110245315A1,COC(=O)C=Cc1ccc2c(c1)CCN2S(=O)(=O)c1ccccc1>>O=C(O)C=Cc1ccc2c(c1)CCN2S(=O)(=O)c1ccccc1,,C1COCCO1,,[Li+].[OH-],,test
US06518282B1,CCCOCCO.O=S(=O)(Cl)c1ccc(Br)cc1>>CCCOCCOS(=O)(=O)c1ccc(Br)cc1,,ClCCl,O,CCN(CC)CC,Cl,test
US20110021537A1,CC(C)(C)OC(=O)CC[C@H](NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1)C(=O)O.CCOC(=O)N1CCNC[C@H]1C>>CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)O)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)NC3CCC3)n(-c3ccccc3)n2)C[C@H]1C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040102635A1,O=C(O)c1ccc(Cl)c(Cn2nnn(C3CC3)c2=O)c1Cl.O=S(Cl)Cl>>O=C(Cl)c1ccc(Cl)c(Cn2nnn(C3CC3)c2=O)c1Cl,CN(C)C=O,ClCCCl,,,,test
US20050234244A1,CC=NNc1ccc(OC)c(F)c1.O=C(Cl)c1ccccc1>>CC=NN(C(=O)c1ccccc1)c1ccc(OC)c(F)c1,,c1ccncc1,,,,test
US20100086506A1,CCCCC[C@@H]1CC[C@@H](C(=O)O)CC1.O=S(Cl)Cl>>CCCCC[C@@H]1CC[C@@H](C(=O)Cl)CC1,,Cc1ccccc1,,c1ccncc1,,test
US20060237368A1,CCCCCC(CCC)COS(=O)(=O)C(F)(F)F.Cc1cncc(C)c1-c1c(C)cc(C(C#N)C#N)cc1C>>CCCCCC(CCC)CN1C=C(C)C(=c2c(C)cc(=C(C#N)C#N)cc2C)C(C)=C1,,CO,ClCCl,C[O-].[Na+],,test
US20030092910A1,COc1nc2ccccc2nc1NC(=O)Oc1ccccc1.c1ccc(N2CCNCC2)cc1>>COc1nc2ccccc2nc1NC(=O)N1CCN(c2ccccc2)CC1,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20150361031A1,CC(C)(C)OC(=O)NCCOCCO.O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1cc(Cl)ccc1O>>CC(C)(C)OC(=O)NCCOCCOc1ccc(Cl)cc1C(=O)Nc1ccc([N+](=O)[O-])cc1Cl,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05576321,Clc1ccc2c(C3CCNCC3)c[nH]c2c1Cl.c1cc(OC[C@@H]2CO2)c2cc[nH]c2c1>>O[C@H](COc1cccc2[nH]ccc12)CN1CCC(c2c[nH]c3c(Cl)c(Cl)ccc23)CC1,,CO,CS(C)=O,,,test
US20160000760A1,O=[N+]([O-])c1cc(Cl)c(-c2ccccc2)c(Cl)c1>>Nc1cc(Cl)c(-c2ccccc2)c(Cl)c1,[Fe],CO,,O,[Cl-].[NH4+],test
US05753665,CC(Br)c1ccnc2ncnn12.Oc1ccc(F)cc1>>CC(Oc1ccc(F)cc1)c1ccnc2ncnn12,,COCCOC,,[H-].[Na+],,test
US20130274218A1,CNC(=O)c1c2cc(C3CC3)c(NS(C)(=O)=O)cc2nn1-c1ccc(Cl)cc1.Cc1ccc(N)nc1.O=Cc1cc(C2CC2)c([N+](=O)[O-])cc1[N+](=O)[O-]>>Cc1ccc(-n2cc3cc(C4CC4)c([N+](=O)[O-])cc3n2)nc1,,CCO,ClCCl,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140200223A1,C[Si](C)(C)N=C=N[Si](C)(C)C.O=C1c2cc(Br)ccc2CC12CCc1c(ccc(F)c1F)C2>>N#C/N=C1\c2cc(Br)ccc2CC12CCc1c(ccc(F)c1F)C2,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20160068496A1,O=C(O)CO.[2H]c1c([2H])c([2H])c(N)c(N)c1[2H]>>OCc1nc2ccccc2[nH]1,,Cl,,O=C([O-])O.[Na+],,test
US20120172351A1,COC(=O)c1cccc(Nc2ccc(C(F)(F)F)cc2NC(=O)[C@H]2CCCO2)c1C>>COC(=O)c1cccc(-n2c([C@H]3CCCO3)nc3cc(C(F)(F)F)ccc32)c1C,,O,,,,test
US20150087585A1,CN(C)C(=O)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1.Cl>>CN(C)C(=O)[C@@H]1CCCNC1.Cl,,CO,,,,test
US20050245438A1,Br.C=Cc1ccc2ccccc2c1>>CC(Br)c1ccc2ccccc2c1,,c1ccccc1,,,,test
US20140343032A1,CC(=O)O.CC(C)(C)OC(=O)N1C2COCC1[C@H](CC#N)C2>>O=C(O)C[C@@H]1CC2COCC1N2,,Cl,,,,test
US04490392,COc1ccc(CC(C)N)cc1OC.O=CC(=O)c1ccccc1OCc1ccccc1>>COc1ccc(CC(C)N=C(OCc2ccccc2)C(=O)c2ccccc2)cc1OC,,CS(C)=O,,O,,test
US05146002,C1CCOC1.CC(=O)C(C)(C)C.COC(=O)c1ccc(OC)c(C(=O)OC)c1>>COc1ccc(C(=O)CC(=O)C(C)(C)C)cc1C(=O)CC(=O)C(C)(C)C,,C1CCOC1,,Cl,[H-].[Na+],test
US20040116415A1,CC(=O)Cl.FC(F)(F)c1cccc(Oc2cccc(CNCCN3CCCCC3)c2)c1>>CC(=O)N(CCN1CCCCC1)Cc1cccc(Oc2cccc(C(F)(F)F)c2)c1,,ClCCl,,c1ccncc1,,test
US04197302,C=CCBr.COC(=O)c1ccc(O)cn1>>C=CCOc1ccc(C(=O)OC)nc1,,CN(C)C=O,,[H-].[Na+],,test
US05221606,COc1cc(C=O)ccc1O[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O.Cc1cccc[n+]1C.[I-]>>COc1cc(C=Cc2cccc[n+]2C)ccc1O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O.[I-],,CO,,C[O-].[Na+],,test
US20150031708A1,COc1cccc(C2(C(=O)O)CC2)c1.COc1ncc(-c2nc(N)ccc2C)cc1C>>COc1cccc(C2(C(=O)Nc3ccc(C)c(-c4cnc(OC)c(C)c4)n3)CC2)c1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=S(Cl)Cl,test
US20090023720A1,CC(C)(CNc1c(N)c(Cl)nc2ccccc12)NS(C)(=O)=O.N#CBr>>Br.CC(C)(Cn1c(N)nc2c(Cl)nc3ccccc3c21)NS(C)(=O)=O,,CCO,,O,,test
US05814653,CCC1CC(C(=O)O)Cc2c1[nH]c1c2CC(OCc2ccccc2)(OCc2ccccc2)C=C1>>CCC1CC(C(=O)O)Cc2c1[nH]c1ccc(OCc3ccccc3)cc21,,[Na+],[OH-],CO,,test
US20090137595A1,CC(C)=CC(=O)Cl.Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1N>>CC(C)=CC(=O)Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)ccc1C,,CC(=O)N(C)C,,,,test
US20090099175A1,CC(=O)c1ccc(F)c(O)c1.CI>>COc1cc(C(C)=O)ccc1F,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20150051211A1,CC(C)(C)OC(=O)N1CCNCC1.ClCC1CC1>>CC(C)(C)OC(=O)N1CCN(CC2CC2)CC1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US06511670B1,CCCCCCCCCCCCCCS.COC(=O)CSCC#CCCl>>CCCCCCCCCCCCCCSCC#CCSCC(=O)OC,,CO,,O,C[O-].[Na+],test
US20070197617A1,C[C@@H](c1ccccc1)[C@@H](C(=O)Nc1ccc(I)cc1Cl)N1C(=O)N[C@H](c2ccc(OCCO)cc2)C1=O>>C[C@@H](c1ccccc1)[C@@H](C(=O)Nc1ccc(I)cc1Cl)N1C(=O)N[C@@H](c2ccc(OCCO)cc2)C1=O,,CO,,,,test
US20080051418A1,CCOC(=O)CBr.CCOc1n[nH]cc1C(=O)NCc1ccc(Cl)cc1Cl>>CCOC(=O)Cn1cc(C(=O)NCc2ccc(Cl)cc2Cl)c(OCC)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110105459A1,CNC(=O)c1ccc(Cl)cn1.O=C(N1CCN(C2CCC2)CC1)N1CC(O)C1>>CNC(=O)c1ccc(OC2CN(C(=O)N3CCN(C4CCC4)CC3)C2)cn1,,CN(C)C=O,,,,test
US20130005743A1,COc1ccc(-n2nc(C)c3c(Br)ccnc32)cc1.N#C[Cu]>>COc1ccc(-n2nc(C)c3c(C#N)ccnc32)cc1,,CN(C)C=O,O,,,test
US20120226035A1,CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)C1CCN(CCn2c(=O)ccc3ncc(Br)cc32)CC1.CCCC[Sn](CCCC)(CCCC)c1ncco1>>CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)C1CCN(CCn2c(=O)ccc3ncc(-c4ncco4)cc32)CC1,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,C1COCCO1,,,,test
US20140249139A1,CN1CCNCC1.O=C(O)c1cccc(-c2ncnc3ccc(Br)cc23)c1>>CN1CCN(C(=O)c2cccc(-c3ncnc4ccc(Br)cc34)c2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04780452,Clc1ccnc2[nH]cnc12.Nc1ccccc1>>c1ccc(Nc2ccnc3[nH]cnc23)cc1,,c1ccccc1,,,,test
US20120157460A1,CC(C)(C)OC(=O)NCC(=O)O.Nc1cc(Br)ccc1NCCO>>CC(C)(C)OC(=O)NCC(=O)Nc1cc(Br)ccc1NCCO,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05047411,C1CCNCC1.C=O.CCNc1nc2ccc(CCc3ccco3)cc2o1>>CCNc1nc2ccc(CCc3ccc(CN4CCCCC4)o3)cc2o1,,CC(=O)O,,Cl,,test
US20120316147A1,CCOC(=O)C(CC)(CC)NC(=O)c1ccc(C(F)(F)F)c(OCC2CC2)n1>>CCC(CC)(NC(=O)c1ccc(C(F)(F)F)c(OCC2CC2)n1)C(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20150166512A1,CCOC(=O)c1cc[nH]c1-c1ccccc1.O=S(=O)(Cl)c1ccccc1>>CCOC(=O)c1ccn(S(=O)(=O)c2ccccc2)c1-c1ccccc1,,CCOC(C)=O,,CN(C)C=O,O,test
US20050222247A1,COC(=O)c1ccc(N(C)c2ccc3c(c2)CC[C@H](CNC[C@H](O)COc2ccccc2)O3)cc1.Cl>>CN(c1ccc(C(=O)O)cc1)c1ccc2c(c1)CC[C@H](CNC[C@H](O)COc1ccccc1)O2.Cl,,C1COCCO1,CO,[Na+].[OH-],,test
US20110144068A1,C[Si](C)(C)C#Cc1c[nH]nc1-c1cccc([N+](=O)[O-])c1>>C#Cc1c[nH]nc1-c1cccc([N+](=O)[O-])c1,,CO,,[F-].[K+],,test
US20140066432A1,CCOC(=O)Nc1ccc(-c2ccc(N)c(/C=C(\CC#N)C(=O)OCC)c2)cc1>>CCOC(=O)Nc1ccc(-c2ccc3c(c2)C=C(C(=O)OCC)CC(N)=N3)cc1,,CC(=O)O,,,,test
US20080200448A1,CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccccc3)CC2)nc1CCl.O=C1CCC(=O)N1>>CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccccc3)CC2)nc1CN1C(=O)CCC1=O,,CCO,,[I-].[Na+],,test
US06197748B1,Cc1ccc(S(=O)(=O)NC(=N)NCCC[C@@H](NC(=O)OC(C)(C)C)C(=O)O)cc1.NCC(=O)OCc1ccccc1>>Cc1ccc(S(=O)(=O)NC(=N)NCCC[C@@H](NC(=O)OC(C)(C)C)C(=O)NCC(=O)OCc2ccccc2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20080269214A1,COC(=O)c1cc(-c2ccc([N+](=O)[O-])cc2)cnc1Cl.NCCN1CCOCC1>>COC(=O)c1cc(-c2ccc([N+](=O)[O-])cc2)cnc1NCCN1CCOCC1,,CCOC(C)=O,COCCOC,CCN(C(C)C)C(C)C,,test
US20040138223A1,COc1ccc2c(c1)C(C(=O)N(Cc1ccc(N(C)C)cc1)c1ccc(C(C)C)cc1)CCC2>>CC(C)c1ccc(N(Cc2ccc(N(C)C)cc2)C(=O)C2CCCc3ccc(O)cc32)cc1,,ClCCl,,BrB(Br)Br,,test
US20080280876A1,CC(C)(C)OC(=O)COc1ccc(C(=O)OCc2ccccc2)cc1>>CC(C)(C)OC(=O)COc1ccc(C(=O)O)cc1,[Pd],CO,,,,test
US20050261331A1,CN1CCNCC1.ClCCNc1ccc(-c2[nH]c3ncc(Cl)cc3c2-c2cncnc2)cc1>>CN1CCN(CCNc2ccc(-c3[nH]c4ncc(Cl)cc4c3-c3cncnc3)cc2)CC1,,CN1CCCC1=O,,,,test
US03966713,C#C[C@]1(O)CC[C@H]2[C@@H]3[C@@H]4O[C@@H]4C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](F)C[C@@]21C.Cl>>C#C[C@]1(O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](F)C[C@@]21C,,CC(=O)O,,,,test
US20070298501A1,O=[N+]([O-])c1c(Cl)c(Cl)c(Cl)c2c1oc1cc(Cl)c(Cl)c(Cl)c12>>Nc1c(Cl)c(Cl)c(Cl)c2c1oc1cc(Cl)c(Cl)c(Cl)c12,,CCO,,,,test
US20040235926A1,CI.O=C(NC1CC2CCC1C2)c1nn(-c2ccccc2Cl)c(Oc2ccc3ccccc3c2)c1CO>>COCc1c(C(=O)NC2CC3CCC2C3)nn(-c2ccccc2Cl)c1Oc1ccc2ccccc2c1,,C1CCOC1,,[H-].[Na+],,test
US05707991,COC(=O)C1CC(C(=O)OC(C)(C)C)N(C(=O)CNC(=O)Nc2cccc(C)c2)C1c1ccccc1>>Cc1cccc(NC(=O)NCC(=O)N2C(C(=O)OC(C)(C)C)CC(C(=O)O)C2c2ccccc2)c1,,CO,O,[K+].[OH-],,test
US20100093811A1,CC(C)CCN(C(CCCC=N[S+]([O-])C(C)(C)C)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)S(=O)(=O)c1ccc(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1.CC[Mg]Br>>CC[C@@H](CCC[C@@H](CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)N(CCC(C)C)S(=O)(=O)c1ccc(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1)N[S+]([O-])C(C)(C)C,,ClCCl,,,,test
US04442109,CCOC(=O)c1cnc2cc(CC)ccc2c1O>>CCc1ccc2c(O)c(C(=O)O)cnc2c1,,CC(=O)O,,[Na+].[OH-],,test
US20160257682A1,C1CNCCN1.CC(C)n1nc(I)c2cnc(Cl)cc21>>CC(C)n1nc(N2CCNCC2)c2cnc(Cl)cc21,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US20080300245A1,CN(C)S(=O)(=O)c1ccc2c(C(=O)Cl)cnn2c1.Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1N>>Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1NC(=O)c1cnn2cc(S(=O)(=O)N(C)C)ccc12,,c1ccncc1,,,,test
US20150299230A1,CC(C)(C)OC(=O)c1cc(N(CCOS(C)(=O)=O)CCOS(C)(=O)=O)c(S(C)(=O)=O)cc1[N+](=O)[O-]>>CS(=O)(=O)OCCN(CCOS(C)(=O)=O)c1cc(C(=O)O)c([N+](=O)[O-])cc1S(C)(=O)=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030191013A1,C[Si](C)(C)OCCC1=CCc2ccccc21.[Li]CCCC>>C[Si](C)(C)OCC[c-]1ccc2ccccc21.[Li+],,CCCCCC,CCOCC,,,test
US20150111887A1,CC(C)(C)OC(=O)N1CCN(c2ncc(C(C)(CO)c3ccc(F)cc3)cn2)CC1>>C[C@@](CO)(c1ccc(F)cc1)c1cnc(N2CCNCC2)nc1,,ClCCl,,C1COCCO1,Cl,test
US20050165057A1,C=O.COc1cccc(C2(CNC(=O)Nc3c(C(C)C)cccc3C(C)C)CCNCC2)c1>>COc1cccc(C2(CNC(=O)Nc3c(C(C)C)cccc3C(C)C)CCN(C)CC2)c1,,CO,,O,[BH3-]C#N.[Na+],test
US20150050325A1,CC(C)(C)OC(=O)N1CCN(c2cc(=O)n3nc(-c4cc(N)cc(Br)c4)sc3n2)CC1.CC(C)(C)OC(=O)NCC(=O)O>>NCC(=O)Nc1cc(Br)cc(-c2nn3c(=O)cc(N4CCNCC4)nc3s2)c1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070276000A1,CCCCC#Cc1ccccc1C(=O)N(C)OC.COc1ccc(C[Mg]Cl)cc1>>CCCCC#Cc1ccccc1C(=O)Cc1ccc(OC)cc1,,C1CCOC1,,,,test
US06156774,C1CCOC1.CCOC(C)=O.O=Cc1ccccc1.[Li]CCCC>>OC(c1ccccc1)c1cccc(C2OCCO2)c1,,C1CCOC1,,CCCCCC,,test
US07034015B2,Brc1ccccc1COCCOCCOC1CCCCO1.C1=COCCC1>>Brc1ccccc1COCCOCCOCCOC1CCCCO1,,C1CCOC1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05786353,O=C(Cl)c1ccc(NC(=O)c2cc(Cl)ccc2Cl)cc1.c1ccc2c(c1)NCCc1cncnc1-2>>NC(=O)c1cc(Cl)cc(-c2ccc(C(=O)N3CCc4cncnc4-c4ccccc43)cc2)c1Cl,,c1ccncc1,,,,test
US20140135374A1,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21.C[C@H]1CCCC(C)(C)[C@@H]1[C@@H](O)c1ccsc1>>C[C@H]1CCCC(C)(C)[C@@H]1C(=O)C1CCCCC1,,ClCCl,,O=C([O-])O.[Na+],,test
US20140364466A1,Cc1cc(C2=NSC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(=O)OC(C)(C)C.O=S(=O)(c1ccccc1)N(F)S(=O)(=O)c1ccccc1>>Cc1cc(C2=NSC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2F)ccc1C(=O)OC(C)(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20060258666A1,C[Si](C)(C)CCOCn1cc(C#N)nc1C(=O)Nc1ccc(-c2ccc(NS(C)(=O)=O)cc2)cc1C1=CCCCC1>>CS(=O)(=O)Nc1ccc(-c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)cc1,,CCOC(C)=O,ClCCl,,,test
US20150038528A1,CCOC(=O)C(C)(C)CN.CCc1ccccc1Oc1ccc2c(O)c(C(=O)OC)nc(C#N)c2c1>>CCOC(=O)C(C)(C)CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3CC)ccc2c1O,,CCO,,,,test
US20100105617A1,C#CCOc1cccc(C(=O)ON2C(=O)CCC2=O)c1.CC(=O)NCCOCCOCCOCCOCCOCCOCCOCCN>>C#CCOc1cccc(C(=O)NCCOCCOCCOCCOCCOCCOCCOCCNC(C)=O)c1,,ClCCl,,CCN(CC)CC,,test
US20020161022A1,Cl[Cu].Nc1ccc2[nH]ncc2c1>>Clc1ccc2[nH]ncc2c1,Cl[Cu],O,,Cl,O=N[O-].[Na+],test
US05244908,CC(=O)OC(C)=O.OCCCSc1cccc2nccn12>>CC(=O)OCCCSc1cccc2nccn12,,ClCCl,,CCN(CC)CC,,test
US20040122005A1,CI.COC(=O)CC(SC(C)=O)C1CC(c2ccc(OCc3cc(C)nc4ccccc34)cc2)=NO1>>COC(=O)CC(SC)C1CC(c2ccc(OCc3cc(C)nc4ccccc34)cc2)=NO1,,CO,,C[O-].[Na+],,test
US05741796,CCOC(=O)Cc1cn(Cc2ccccc2)cn1>>OCCc1cn(Cc2ccccc2)cn1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04988689,CCOC(=O)N1CCC(N=C=S)C1.Cc1ccc(CNc2ccccc2N)o1>>CCOC(=O)N1CCC(NC(=S)Nc2ccccc2NCc2ccc(C)o2)C1,,C1CCOC1,,,,test
US05521147,CC1(C)Oc2c(N)cccc2C1=S.O=C1CCC(=O)N1Cl>>CC1(C)Oc2c(N)ccc(Cl)c2C1=S,,CN(C)C=O,,,,test
US20080161302A1,CN(Cc1ccccc1)C(=O)c1cccc([N+](=O)[O-])c1>>CN(Cc1ccccc1)C(=O)c1cccc(N)c1,,CCOC(C)=O,,,,test
US20060293394A1,COc1cc(C2(O)CCCc3c(ccc(OC)c3OC(C)C)C2)cc(OC)c1OC>>COc1cc(C2=Cc3ccc(OC)c(OC(C)C)c3CCC2)cc(OC)c1OC,,CC(=O)O,O,,,test
US04876343,COC(=O)[C@@H](N)Cc1ccccc1.Cl>>COC(=O)[C@@H](N)CC1CCCCC1.Cl,[Rh],CO,,[H][H],,test
US20030211421A1,CC(=O)Cl.Oc1ccc(OCc2ccccc2)cc1>>CC(=O)Oc1ccc(OCc2ccccc2)cc1,,O,,C1CCOC1,CCN(CC)CC,test
US20060128710A1,CC(C)(C)c1ccc(Nc2nc(-c3ccccc3)nc3c2CCN(Cc2ccccc2)C3)cc1>>CC(C)(C)c1ccc(Nc2nc(-c3ccccc3)nc3c2CCNC3)cc1,,CCOC(C)=O,CO,CC(=O)O,,test
US20070060607A1,CCOC(=O)c1cnc(Cl)c2c(COc3cccc(OCc4ccc(Cl)cc4)c3)csc12.N>>CCOC(=O)c1cnc(N)c2c(COc3cccc(OCc4ccc(Cl)cc4)c3)csc12,,C1COCCO1,,,,test
US20110294853A1,COC(=O)c1cc(C)ccc1NC(=O)c1cccc(Cl)c1.O=C1CCC(=O)N1Br>>COC(=O)c1cc(CBr)ccc1NC(=O)c1cccc(Cl)c1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20070054935A1,CSc1ccc([Mg]Br)cc1.N#Cc1cccc(-c2ccncc2C=O)c1>>CSc1ccc(C(O)c2cnccc2-c2cccc(C#N)c2)cc1,,C1CCOC1,,,,test
US20140249131A1,CCc1cc2cnc(SC)nc2n(-c2cccc(NC(=O)OC(C)(C)C)c2)c1=O.O=C(OO)c1cccc(Cl)c1>>CCc1cc2cnc(S(C)=O)nc2n(-c2cccc(NC(=O)OC(C)(C)C)c2)c1=O,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20040122244A1,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)O)c2)=C(C)C1=O.Nc1ccncc1>>COC1=C(OC)C(=O)C(Cc2ccc(O)c(C(=O)Nc3ccncc3)c2)=C(C)C1=O,,ClCCl,,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US05077402,C1COCCN1.CCC(Cc1ccccc1)(C(=O)c1ccc(F)cc1)N(C)C>>CCC(Cc1ccccc1)(C(=O)c1ccc(N2CCOCC2)cc1)N(C)C,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05185448,C=CCBr.CCCCCCCCCCCCCCCCCC(=O)OC1CCN(O)CC1>>C=CCON1CCC(OC(=O)CCCCCCCCCCCCCCCCC)CC1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20150065705A1,COCOCC1(COCOC)CN(C(=O)OC(C)(C)C)CC=C1c1ccc(F)cc1.O=C(O)C(F)(F)F>>COCOCC1(COCOC)CNCC=C1c1ccc(F)cc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US09248117B2,CC(=O)SCCN1CC(C)(C)NC1=O>>CC1(C)CN(CCS)C(=O)N1,,CO,O,[Na+].[OH-],,test
US20070004725A1,CN(C)C(=O)C(Cc1ccc(Oc2ccccc2CCC(=O)NOCc2ccccc2)cc1)NC(=O)OC(C)(C)C>>CN(C)C(=O)C(Cc1ccc(Oc2ccccc2CCC(=O)NO)cc1)NC(=O)OC(C)(C)C,[Pd],CO,,[H][H],,test
US20080261969A1,Fc1cc2[nH]c(=S)[nH]c2cc1F.O=Cc1ccc([N+](=O)[O-])o1>>O=Cc1ccc(Sc2nc3cc(F)c(F)cc3[nH]2)o1,,C1CCOC1,,[H-].[Na+],,test
US20140242028A1,FC(F)(F)c1ccc(S)cc1.O=[N+]([O-])c1cc(Cl)c(F)c(Cl)c1>>O=[N+]([O-])c1cc(Cl)c(Sc2ccc(C(F)(F)F)cc2)c(Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120015980A1,CCOC(=O)c1cc(N2CCN(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)C2=O)nn1-c1ncccc1Cl>>O=C(O)c1cc(N2CCN(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)C2=O)nn1-c1ncccc1Cl,,CCO,,[Na+].[OH-],,test
US20100113458A1,CNC1CCN(C)C1.COc1ccc(CN(c2cccc(C(=O)O)c2)c2cc(Cl)nn3c(C#N)cnc23)cc1>>COc1ccc(CN(c2cccc(C(=O)N(C)C3CCN(C)C3)c2)c2cc(Cl)nn3c(C#N)cnc23)cc1,,CN(C)C=O,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US05576335,CCCCCCCNC.O=C(Nc1ccc(F)cc1[N+](=O)[O-])Oc1ccccc1>>CCCCCCCN(C)C(=O)Nc1ccc(F)cc1[N+](=O)[O-],,Cc1ccccc1C,,,,test
US20060148858A1,CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO.COC(=O)CCc1cn(C)nc1O>>CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCOc1nn(C)cc1CCC(=O)O,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US06127579,C=COCC.O[C@@H]1c2ccccc2C[C@H]1Cl>>CCOC(C)O[C@@H]1c2ccccc2C[C@H]1Cl,,Clc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US06384065B1,CC(C)c1ccc(OC2CCC3(CC2)SC[C@@H](C(=O)O)N3C(=O)c2ccccc2)cc1.CCO>>CCOC(=O)[C@@H]1CSC2(CCC(Oc3ccc(C(C)C)cc3)CC2)N1C(=O)c1ccccc1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20040158067A1,CCOC(=O)c1c(C#CC(C)(C)O[Si](C)(C)C(C)(C)C)cc(-c2c(CC)cccc2CC)nc1C>>CCOC(=O)c1c(CCC(C)(C)O[Si](C)(C)C(C)(C)C)cc(-c2c(CC)cccc2CC)nc1C,[Pd],CO,,,,test
US20040110945A1,COC(=O)Cc1ccc(N)c(O)c1.Cc1ccc(F)cc1N=C=S>>COC(=O)Cc1ccc2nc(Nc3cc(F)ccc3C)oc2c1,,CO,,,,test
US20110112161A1,CCOC(=O)C(C)Br.COc1cc(F)c(F)cc1-c1ccc(OCc2cccc3[nH]ncc23)cc1>>CCOC(=O)CCn1ncc2c(COc3ccc(-c4cc(F)c(F)cc4OC)cc3)cccc21,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US04777281,CCCC12CCC(=O)C=C1c1c(cc(O)c(Cl)c1Cl)CC2.N#CCCl>>CCCC12CCC(=O)C=C1c1c(cc(OCC#N)c(Cl)c1Cl)CC2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160264554A1,C=CC(=O)Cl.Nc1ccc(C(=O)N[C@H]2CCC[C@@H](Nc3ncc(Cl)c(-c4n[nH]c5ccccc45)n3)C2)cc1>>C=CC(=O)Nc1ccc(C(=O)N[C@H]2CCC[C@@H](Nc3ncc(Cl)c(-c4n[nH]c5ccccc45)n3)C2)cc1,,CN(C)C=O,,CCN(CC)CC,CO,test
US20150148340A1,Cn1c(=O)[nH]c2cc([N+](=O)[O-])ccc21.O=S(=O)(OCC(F)(F)F)C(Cl)(Cl)Cl>>Cn1c(=O)n(CC(F)(F)F)c2cc([N+](=O)[O-])ccc21,,CC#N,CN(C)C=O,Cl,O=C([O-])[O-].[K+].[K+],test
US20150126522A1,COC(=O)c1cc(Br)cc(OC(C)C)c1C>>Cc1c(OC(C)C)cc(Br)cc1C(=O)O,,CO,,Cl,[Na+].[OH-],test
US20130079321A1,Cc1ccc(S(=O)(=O)Cl)cc1.Cn1ncc([N+](=O)[O-])c1N1CCC(O)C(N=[N+]=[N-])CC1>>Cc1ccc(S(=O)(=O)OC2CCN(c3c([N+](=O)[O-])cnn3C)CCC2N=[N+]=[N-])cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US20070276030A1,Cc1ccc(Br)cc1SCC(=O)Cl>>Cc1ccc(Br)c2c1SCC2=O,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US05426226,CC(C)=NO.CCCN(CCC)C1CCc2cccc(C(=O)c3ccccc3F)c2C1>>CCCN(CCC)C1CCc2cccc(C(=O)c3ccccc3ON=C(C)C)c2C1,,C1CCOC1,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US05518653,CCCCCCCC[C@H]1CO[C@H](c2ccc(O)cc2)O[C@@H]1C.CCCC[C@H](F)C(=O)O>>CCCCCCCC[C@H]1CO[C@H](c2ccc(OC(=O)[C@@H](F)CCCC)cc2)O[C@@H]1C,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05057614,Cn1cc(C2=C(c3cn(CCCOS(C)(=O)=O)c4ccccc34)C(=O)NC2=O)c2ccccc21.NC(N)=S>>CS(=O)(=O)O.Cn1cc(C2=C(c3cn(CCCSC(=N)N)c4ccccc34)C(=O)NC2=O)c2ccccc21,,CCO,,,,test
US20080188488A1,N#Cc1ccc(N2CCNCC2)cc1.O=C(Cl)c1ccccc1C(F)(F)F>>N#Cc1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)cc1,,ClCCl,O,CCN(CC)CC,Cl,test
US20110053916A1,C#Cc1cnc(-c2ccc(S(=O)(=O)NCCO[Si](C)(C)C(C)(C)C)s2)nc1Nc1cc(C2CC2)[nH]n1>>C#Cc1cnc(-c2ccc(S(=O)(=O)NCCO)s2)nc1Nc1cc(C2CC2)n[nH]1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100063128A1,C1CCOC1.CCOC(=O)c1cc2ccc(OC)cc2n1CC#N>>CCOC(=O)c1cc2ccc(OC)cc2n1CCNC(C)=O,[Ni],,,,,test
US20160251339A1,O=Cc1c[nH]c2ccc(F)cc12>>Cc1c[nH]c2ccc(F)cc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04818766,COC(=O)C1=C(C)NC(C)=C(C(=O)OCCOc2ccc(OCCNC(=O)OC(C)(C)C)cc2)C1c1cccc([N+](=O)[O-])c1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OCCOc2ccc(OCCN)cc2)C1c1cccc([N+](=O)[O-])c1,,O=CO,,,,test
US03941828,CCC#CCC1(Cl)C(=O)CCCC1=O>>CCC#CCC1=CCCC1=O,,Cc1ccccc1C,,O=C([O-])[O-].[Na+].[Na+],,test
US20090137557A1,Cc1nc(-c2cccc(F)c2O)n(CCc2ccccc2)c(=O)c1-c1ccc2ncccc2c1>>Cc1nc(-c2cccc(F)c2O)n(CCc2ccccc2)c(=O)c1-c1ccc2c(c1)CCCN2,[Pd],CCO,,,,test
US20040236109A1,COc1ccccc1C(=O)Nc1ccc2c(c1)C(C)(c1ccccc1)CC(C)(C)N2C(C)=O>>CC(=O)N1c2ccc(NC(=O)c3ccccc3O)cc2C(C)(c2ccccc2)CC1(C)C,,ClCCl,,BrB(Br)Br,O,test
US20140256729A1,Cc1cccc(CNc2ccc([C@@H]3C[C@H]3N(C(=O)OC(C)(C)C)C3CCC(NC(=O)OC(C)(C)C)CC3)cn2)c1>>Cc1cccc(CNc2ccc([C@@H]3C[C@H]3NC3CCC(N)CC3)cn2)c1,,C1COCCO1,,Cl,,test
US20090036492A1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.Cc1c(C)c(C=O)c2ccccc2c1C>>COc1cc(O)c2c(c1C(=O)NCc1c(C)c(C)c(C)c3ccccc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20030027849A1,C1CCOC1.O=C(O)CC(F)(F)C(=O)O>>COC(=O)C(F)(F)CC(=O)O,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US06756388B1,CC(=O)Nc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(O)cc3)sc2c1>>Nc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(O)cc3)sc2c1,,CCO,,[Na+].[OH-],,test
US03937713,CC(=O)NN.Cc1ccc(Cl)c(N=C=S)c1>>CC(=O)NNC(=S)Nc1cc(C)ccc1Cl,,C1CCOC1,,,,test
US20160272655A1,CO.O=C(O)c1ncc(Cl)cc1F>>COC(=O)c1ncc(Cl)cc1F,,CCOCC,CO,C[Si](C)(C)C=[N+]=[N-],,test
US20060025474A1,CCC(CC)(c1ccc(/C=C/C(OCOC)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(OS(=O)(=O)C(F)(F)F)c(C)c1>>CCC(CC)(c1ccc(/C=C/C(O)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(OS(=O)(=O)C(F)(F)F)c(C)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110201593A1,O=C(O)[C@@H]1CCCN1.O=C1CCC1>>O=C(O)[C@@H]1CCCN1C1CCC1,[Pd],CO,,,,test
US20150065482A1,CC1(C)CCc2c(c(C(=O)O)nn2COCC[Si](C)(C)C)C1>>CC1(C)CCc2[nH]nc(C(=O)O)c2C1,,CCO,,C1COCCO1,Cl,test
US20140080808A1,CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(C3(c4ccc(B5OC(C)(C)C(C)(C)O5)cc4)CC3)n2CCS1.Cc1cccc(Br)n1>>Cc1cccc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO[Si](C)(C)C(C)(C)C)C5)CC3)cc2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20020193614A1,C=O.O=C(NCc1ccc2c(c1)OCO2)c1cc([N+](=O)[O-])ccc1NC1CCNCC1>>CN1CCC(Nc2ccc([N+](=O)[O-])cc2C(=O)NCc2ccc3c(c2)OCO3)CC1,CC(=O)O,CO,,[BH3-]C#N.[Na+],,test
US20120095064A1,Fc1c(Cl)cccc1CBr.O=C1c2ccccc2C(=O)N1c1cc[nH]n1>>O=C1c2ccccc2C(=O)N1c1ccn(Cc2cccc(Cl)c2F)n1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060084654A1,COC(=O)c1cccc(COc2cccc(-c3nc(C4CCC4)n4ccnc(N)c34)c2)c1.N>>NC(=O)c1cccc(COc2cccc(-c3nc(C4CCC4)n4ccnc(N)c34)c2)c1,,CO,,,,test
US20140187542A1,O=c1cnc2cc(F)c(F)cc2n1CCC1OCCO1>>O=CCCn1c(=O)cnc2cc(F)c(F)cc21,,C1COCCO1,,Cl,O=C([O-])O.[Na+],test
US05162349,Cc1nnc(-c2nnc(S)o2)o1.FC(F)=C(F)CCBr>>Cc1nnc(-c2nnc(SCCC(F)=C(F)F)o2)o1,,CN(C)C=O,,C1COCCO1,,test
US20020143186A1,COC(=O)c1ccc(CNc2ccc(C3=CCCCC3)cc2)cc1.O=C(O)c1cccc(Br)c1.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>COC(=O)c1ccc(CN(C(=O)Nc2cccc(Br)c2)c2ccc(C3=CCCCC3)cc2)cc1,,CCOC(C)=O,Cc1ccccc1,CCN(CC)CC,,test
US20100305123A1,CC(=O)c1ccc(N2CCN(C)CC2)cc1.CC(C)(C)OC(=O)/C=C/c1cccc(C=O)n1>>CN1CCN(c2ccc(C(=O)CC(O)c3cccc(/C=C/C(=O)OC(C)(C)C)n3)cc2)CC1,,CCO,O,[K+].[OH-],,test
US20140094453A1,CC(C)CC(=O)N1CCC[C@H](COc2cccc(N)c2C#N)C1.NS(=O)(=O)Cl>>CC(C)CC(=O)N1CCC[C@H](COc2cccc(NS(N)(=O)=O)c2C#N)C1,,CC(=O)N(C)C,,O,,test
US20090111798A1,COC(=O)[C@H]1CCCC[C@H]1N(Cc1ccc(F)cc1)C(=O)CC1=NS(=O)(=O)c2cc(NS(C)(=O)=O)ccc2N1>>CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)[C@H]3CCCC[C@H]3N(Cc3ccc(F)cc3)C1=O)N2,,CCO,,C,C[O-].[Na+],test
US20110237573A1,Brc1ccnnc1.CCOC(=O)Cc1ccc(B(O)O)cc1>>CCOC(=O)Cc1ccc(-c2ccnnc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US04436748,CCOC(=O)COc1cc2cc(C(O)CC)sc2c(Cl)c1Cl>>CCC(O)c1cc2cc(OCC(=O)O)c(Cl)c(Cl)c2s1,,CCO,CCOCC,Cl,[Na+].[OH-],test
US20100267774A1,Cc1ccc(S(=O)(=O)O)cc1.N[C@H](C(=O)O)c1ccccc1.OC1CCCC1>>Cc1ccc(S(=O)(=O)[O-])cc1.[NH3+][C@H](C(=O)OC1CCCC1)c1ccccc1,,C1CCCCC1,,,,test
US20040259912A1,CCC(=O)c1cc(N)ccc1OCc1ccc(C(C)C)cc1.COc1ccc(N=C=O)cc1OC>>CCC(=O)c1cc(NC(=O)Nc2ccc(OC)c(OC)c2)ccc1OCc1ccc(C(C)C)cc1,,C1CCOC1,,,,test
US20050245515A1,OC(c1ccc2c(c1)CCN2Cc1ccccc1)(C(F)(F)F)C(F)(F)F>>OC(c1ccc2c(ccn2Cc2ccccc2)c1)(C(F)(F)F)C(F)(F)F,O=[Mn]=O,Cc1ccccc1,,,,test
US04720495,CCOC(=O)c1cn2c3c(c(Cl)c(F)cc3c1=O)C(=O)CC2CC>>CCC1CC(=O)c2c(Cl)c(F)cc3c(=O)c(C(=O)O)cn1c23,,CC(=O)O,Cl,,,test
US20060217372A1,CCC[Mg]Cl.COc1ccc(CN2CCCC(C(=O)N(C)OC)C2)cc1>>CCCC(=O)C1CCCN(Cc2ccc(OC)cc2)C1,,C1CCOC1,,,,test
US20160137653A1,CC1(C)OB(C2=CCC3(CC2)OCCO3)OC1(C)C.Fc1ccc2nccc(Cl)c2c1>>Fc1ccc2nccc(C3=CCC4(CC3)OCCO4)c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20060172994A1,COc1ccc2nc[nH]c(=O)c2c1.ClP(Cl)(Cl)(Cl)Cl>>COc1ccc2ncnc(Cl)c2c1,,ClCCl,,ClCCCl,,test
US20060094767A1,Cc1ccc(S(=O)(=O)OC[C@H]2CO2)cc1.O=[N+]([O-])c1c[nH]c(Cl)n1>>Cc1ccc(S(=O)(=O)OC[C@H](O)Cn2cc([N+](=O)[O-])nc2Cl)cc1,,CC#N,,O=C([O-])O.[Na+],,test
US05232948,CCOC(=O)Cc1cc(OC)cc(OC)c1>>CCOC(=O)Cc1cc(O)cc(O)c1,,ClCCl,,BrB(Br)Br,,test
US20100029611A1,COC(=O)[C@@H]1C[C@H](Nc2ccc(-c3nc4ccc(C5(c6ccccc6)CC5)nc4s3)c(F)c2)C1>>O=C(O)[C@@H]1C[C@H](Nc2ccc(-c3nc4ccc(C5(c6ccccc6)CC5)nc4s3)c(F)c2)C1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20030055085A1,CCN(CC)CC.CN(C)C=O.O=C(Cl)c1cncc(Br)c1.O=C(O)c1cncc(Br)c1>>Brc1cncc(-c2nc(-c3ccccn3)no2)c1,,ClCCl,,O,,test
US20100184764A1,CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@@H](N2CCCCC2=O)CC1.Clc1cc(Br)ccc1CBr>>CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@@H](N2CCCC(Cc3ccc(Br)cc3Cl)C2=O)CC1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US05874431,Nc1ccc(C(=O)O)cc1.Nc1ccccc1O>>Nc1ccc(-c2nc3ccccc3o2)cc1,,O=C([O-])O,[Na+],,,test
US20140349989A1,CCOC(=O)c1cn(CCCCCN)c2ccccc12.NCc1cccnc1.O=C(Cl)OC(Cl)(Cl)Cl>>CCOC(=O)c1cn(CCCCCNC(=O)NCc2cccnc2)c2ccccc12,,ClCCl,,CCN(CC)CC,,test
US20070259898A1,COC(OC)N(C)C.Cc1cc(-c2ccccc2F)ncc1[N+](=O)[O-]>>CN(C)C=Cc1cc(-c2ccccc2F)ncc1[N+](=O)[O-],,CN(C)C=O,,,,test
US20040082619A1,Cc1ccc(O)cn1.Cl>>Cc1ccc(O)c(Cl)n1,,CO,,C,,test
US20160251320A1,COc1cccc2c1n(O)c1cccc(=O)c-1[n+]2[O-].OCC1CO1>>COc1cccc2c1[n+]([O-])c1cccc(OCC(O)CO)c1[n+]2[O-],,CN(C)C=O,,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US20030083333A1,CC(C)(C)O.Nc1ccc(C(=O)O)c2ccccc12>>CC(C)(C)OC(=O)c1ccc(N)c2ccccc12,,CCN(CC)CC,CCOC(C)=O,Cl,O=C(n1ccnc1)n1ccnc1,test
US20110312935A1,N#Cc1ccc(NC(=O)c2ccc([N+](=O)[O-])c([N+](=O)[O-])c2)nc1>>N#Cc1ccc(NC(=O)c2ccc(N)c(N)c2)nc1,[Fe],CCO,,CC(=O)O,,test
US05556864,BrCC1CO1.Oc1ccccc1CCCCc1cccc(Cl)c1>>Clc1cccc(CCCCc2ccccc2OCC2CO2)c1,,CC(=O)N(C)C,,CC(C)(C)[O-].[K+],,test
US20110028447A1,CC(C)(C)OC(=O)N[C@H](c1nnc(NC(=O)C2CC2)o1)C(C)(C)C.Cl>>CC(C)(C)[C@H](N)c1nnc(NC(=O)C2CC2)o1.Cl,,C1COCCO1,,,,test
US20110274638A1,CC(C)(C)OC(=O)N1CC(=O)C1.Fc1ccccc1Br>>CC(C)(C)OC(=O)N1CC(O)(c2ccccc2F)C1,,C1CCOC1,,CC(C)[Mg]Cl,[Cl-].[NH4+],test
US20150315198A1,O=Cc1cc2ccc(Cl)nc2s1>>OCc1cc2ccc(Cl)nc2s1,,CO,,[BH4-].[Na+],,test
US04918074,CCOC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(C)=O.Nc1nnn[nH]1>>CCOC(=O)C1=C(C)Nc2nnnn2C1c1cccc([N+](=O)[O-])c1,,CCO,,,,test
US05608056,C=CCOC(=O)N1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)C[C@H]1CC#N.OO>>C=CCOC(=O)N1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)C[C@H]1CC(N)=O,,CS(C)=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20110065702A1,C[Si](C)(C)CCOCn1nc(CCc2ccncc2)c2ccc(C=C3C(=O)Nc4ccccc43)cc21>>O=C1Nc2ccccc2C1=Cc1ccc2c(CCc3ccncc3)n[nH]c2c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100286145A1,C=C(C)c1cc(CCl)cc(N(C)S(C)(=O)=O)c1.[N-]=[N+]=[N-]>>C=C(C)c1cc(CN=[N+]=[N-])cc(N(C)S(C)(=O)=O)c1,,CN(C)C=O,,CCOC(C)=O,O,test
US05086065,COc1ccc(OC)c(C=O)c1.O=C(O)CC(=O)O>>COc1ccc(OC)c(/C=C/C(=O)O)c1,,O,c1ccncc1,C1CCNCC1,Cl,test
US06432993B1,CN(C)c1cccc(Oc2ccc(N)c(N(C)C(=O)OC(C)(C)C)c2)c1.O=C(O)COc1ccc(CC2SC(=O)NC2=O)cc1>>CN(C)c1cccc(Oc2ccc(NC(=O)COc3ccc(CC4SC(=O)NC4=O)cc3)c(N(C)C(=O)OC(C)(C)C)c2)c1,,C1CCOC1,,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20080181923A1,Cl.NCCCc1c[nH]c(N)n1.O=C(c1ccc[nH]1)C(Cl)(Cl)Cl>>Cl.Nc1nc(CCCNC(=O)c2ccc[nH]2)c[nH]1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US05324735,CCOC(=O)c1cn(C(C)CO)c2c(F)c(F)c(F)cc2c1=O.O=S(Cl)Cl>>CCOC(=O)c1cn(C(C)CCl)c2c(F)c(F)c(F)cc2c1=O,,ClC(Cl)Cl,,,,test
US05919779,Brc1cscc1Br.CCCC[Sn](CCCC)(CCCC)c1cccnc1F>>Fc1ncccc1-c1cscc1Br,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,CN1CCCC1=O,[F-].[K+],,test
US04600429,NCCCCN.O.O=P(O)(O)CCl>>NCCCCNCP(=O)(O)O.O,,O,,,,test
US06414145B1,COC(=O)c1cc(CBr)cc(-c2ccccc2)c1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>COC(=O)c1cc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc(-c2ccccc2)c1.[Br-],,Cc1ccccc1,,,,test
US20120190649A1,CCOC(=O)CNCc1ccc2cc(OC3CCC(C(C)(C)C)CC3)ccc2c1>>CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3cc(CNCC(=O)O)ccc3c2)CC1,,CO,,Cl,[Li+].[OH-],test
US20080015203A1,COC[C@H](C)Oc1cc(Oc2ccc(-c3ncon3)cc2)cc(C(=O)Nc2ccn(C)n2)c1>>C[C@@H](CO)Oc1cc(Oc2ccc(-c3ncon3)cc2)cc(C(=O)Nc2ccn(C)n2)c1,,CC#N,CCOC(C)=O,C[Si](C)(C)I,,test
US20100210622A1,CC(C)(C)OC(=O)c1nc(N2CCc3cccc(C(=O)/N=c4\sc5ccccc5n4COCC[Si](C)(C)C)c3C2)ccc1CCC=O>>CC(C)(C)OC(=O)c1nc(N2CCc3cccc(C(=O)/N=c4\sc5ccccc5n4COCC[Si](C)(C)C)c3C2)ccc1CCCO,,C1CCOC1,CO,[BH4-].[Na+],,test
US05840732,O=C1COC(=O)N1CCCCOc1cccn2ccnc12.O=CCCc1ccccc1>>O=C1OC(=CCCc2ccccc2)C(=O)N1CCCCOc1cccn2ccnc12,,CCO,,C1CCNC1,,test
US05371080,FC(F)(F)c1cccc2nc(Cl)nc(N3CCOCC3)c12.[C-]#[N+]Cc1nc(C2CC2)no1>>FC(F)(F)c1cccc2c1c(N1CCOCC1)nc1c(-c3nc(C4CC4)no3)ncn12,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20110144105A1,CCSC(=O)C(C(=O)SCC)C1CCC(=O)C1.OCCO>>CCSC(=O)C(C(=O)SCC)C1CCC2(C1)OCCO2,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20140155391A1,COC(=O)c1ccc([N+](=O)[O-])cc1OCC1CC1>>COC(=O)c1ccc(N)cc1OCC1CC1,[Pd],CO,,,,test
US20050080124A1,CCN(C=CC(=O)c1cc(NC(=O)Nc2ccc(F)cc2F)ccc1OC)CC.NN>>COc1ccc(NC(=O)Nc2ccc(F)cc2F)cc1-c1ccn[nH]1,,CC(=O)O,CO,,,test
US20080262056A1,CN1C(=O)Cc2cc(NC[C@@H](O)CNC(=O)OC(C)(C)C)cc(F)c21.O=C(Cl)Cl>>CN1C(=O)Cc2cc(N3C[C@H](CNC(=O)OC(C)(C)C)OC3=O)cc(F)c21,,ClCCl,,CCN(CC)CC,,test
US20120142717A1,COC(=O)C(C=O)Cc1cnc(OC)nc1.Cc1ccc(Oc2ccc(CCOC(=N)N)cc2)cc1F>>COc1ncc(Cc2c[nH]c(OCCc3ccc(Oc4ccc(C)c(F)c4)cc3)nc2=O)cn1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20040122063A1,CN(C)C(=O)[C@@H]1CC[C@H](NC(=O)OCc2ccccc2)[C@@H](NC(=O)OC(C)(C)C)C1>>CN(C)C(=O)[C@H]1CC[C@H](N)[C@H](NC(=O)OC(C)(C)C)C1,[Pd],C1CCOC1,,[H][H],,test
US20040204397A1,COC(=O)C(NC(=O)OCc1ccccc1)P(=O)(OC)OC.C[Si](C)(C)CCS(=O)(=O)n1ccc2cc(C=O)ccc21>>COC(=O)C(=Cc1ccc2c(ccn2S(=O)(=O)CC[Si](C)(C)C)c1)NC(=O)OCc1ccccc1,,C1CCOC1,,CN(C)C(=N)N(C)C,,test
US20020025965A1,O=[N+]([O-])c1ccc2c(c1)CC(c1c[nH]cn1)C2>>Nc1ccc2c(c1)CC(c1c[nH]cn1)C2,[Pd],CCO,,Cl,,test
US20060094707A1,COC(=O)c1cccc(Cl)c1N>>Nc1c(Cl)cccc1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20160221945A1,COc1cnc(C#N)cc1-c1ccc(C(F)(F)F)nc1.Cl>>COc1cnc(CN)cc1-c1ccc(C(F)(F)F)nc1.Cl,[Pd],CO,,,,test
US05316755,CCCCCCCCC(C)O.CS(=O)(=O)Cl>>CCCCCCCCC(C)OS(C)(=O)=O,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20100130447A1,COC(=O)c1cccc(C(C)Nc2cncc(Cl)n2)c1>>CC(Nc1cncc(Cl)n1)c1cccc(C(=O)O)c1,,CO,ClCCl,[Na+].[OH-],,test
US20120071474A1,COc1cc(-c2cnc3ccc(Br)cn23)cnc1OC.O=C1NCCO1>>COc1cc(-c2cnc3ccc(N4CCOC4=O)cn23)cnc1OC,[Cu]I,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=C([O-])[O-].[K+].[K+],test
US20140018345A1,CC(=O)Nc1nc2c(-c3cccc(C(F)(F)F)c3)c(C)c(C(N)=O)cn2n1.COC(OC)N(C)C>>CC(=O)Nc1nc2c(-c3cccc(C(F)(F)F)c3)c(C)c(C(=O)/N=C/N(C)C)cn2n1,,C1CCOC1,,,,test
US20090186917A1,CC(C)C[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C.Nc1ccc2ccncc2c1>>CC(C)C[C@@H](C(=O)Nc1ccc2ccncc2c1)N(C)C(=O)OC(C)(C)C,CN(C)c1ccncc1,CN(C)C=O,,ClCCCl,,test
US20050043537A1,CCOC(OCC)OCC.CCOc1ccc(N)cc1I.COc1cc(NC(=O)CC#N)c(Cl)cc1Cl>>CCOc1ccc(NC=C(C#N)C(=O)Nc2cc(OC)c(Cl)cc2Cl)cc1I,,CC(C)O,,,,test
US20110086839A1,CC(C)(C)OC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.N#Cc1ccc2c(C=O)c[nH]c2c1>>CC(C)(C)OC(=O)/C=C/c1c[nH]c2cc(C#N)ccc12,,CC#N,,,,test
US20100317651A1,CC(C)N(C)c1cnc2c(n1)OCCN(Cc1ccccc1)C2.O=C1CCC(=O)N1Cl>>CC(C)N(C)c1nc2c(nc1Cl)CN(Cc1ccccc1)CCO2,,O,,CC#N,,test
US04643990,CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)OC(C)(C)C>>CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)O,,O=C(O)C(F)(F)F,,,,test
US20080121870A1,CC1(COCCCCCCBr)COC1.O=Cc1ccc(O)cc1>>CC1(COCCCCCCOc2ccc(C=O)cc2)COC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090030082A1,COC(=O)Cc1cccc(OCCCN(Cc2cccc(F)c2F)CC(c2ccccc2)c2ccccc2)c1>>O=C(O)Cc1cccc(OCCCN(Cc2cccc(F)c2F)CC(c2ccccc2)c2ccccc2)c1,,CO,,[Na+].[OH-],,test
US20090203697A1,CCN(C(C)C)C(C)C.CN(C)C=O.ClCCCl.NC1c2ccccc2-c2ccccc21.O=C(O)C=Cc1ccccc1.On1nnc2ccccc21>>COc1cc(/C=C/C(=O)NC2c3ccccc3-c3ccccc32)ccc1-n1cnc(C)n1,,ClCCCl,,Cl,,test
US05716964,CCOC(=O)C(=O)CBr.CCOP(=O)(Cc1nc(N)ccc1Cl)OCC>>CCOC(=O)c1cn2c(CP(=O)(OCC)OCC)c(Cl)ccc2n1,,CCO,COCCOC,,,test
US20090054456A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Nc1cccc(C(F)(F)F)c1>>CC(C)(C)OC(=O)N1CCC(Nc2cccc(C(F)(F)F)c2)CC1,,ClCCCl,,O=C([O-])O.[Na+],,test
US20020147343A1,NCCNc1cc(-c2ccc[nH]2)c2c3c(ccc(F)c13)NC2=O.O=C(n1ccnc1)n1ccnc1>>O=C1Nc2ccc(F)c3c(N4CCNC4=O)cc(-c4ccc[nH]4)c1c23,,ClCCCl,,,,test
US05449778,Cl.[N-]=[N+]=N[C@@H](C(=O)O)C1c2ccccc2CCc2ccccc21>>Cl.NC(C(=O)O)C1c2ccccc2CCc2ccccc21,[Pd],C1CCOC1,O,[H][H],,test
US06511974B1,Cc1c[nH]cn1.O=C(c1ccc(F)cc1Cl)N1Cc2cccn2Cc2ccccc21>>Cc1cn(-c2ccc(C(=O)N3Cc4cccn4Cc4ccccc43)c(Cl)c2)cn1,,CN(C)C=O,,CCCCCC,[H-].[Na+],test
US20160145247A1,COC(=O)Cc1ccccc1CN(C)c1cccc(-c2cccc([C@@H](C)N)c2F)c1>>C[C@@H](N)c1cccc(-c2cccc(N(C)Cc3ccccc3CC(=O)O)c2)c1F,,CC#N,,[Li+].[OH-],,test
US20020156276A1,COc1cc(CN2CCc3ccc(N4CCN(CCC(c5ccccc5)c5ccccc5)CC4)cc3C2=O)cc(OC)c1>>O=C1c2cc(N3CCN(CCC(c4ccccc4)c4ccccc4)CC3)ccc2CCN1Cc1cc(O)cc(O)c1,,ClCCl,,BrB(Br)Br,,test
US20090312338A1,CC(C)[Si](C(C)C)(C(C)C)n1ccc2c(I)c(Cl)cnc21.O=CC1CCCN(Cc2ccccc2)C1>>CC(C)[Si](C(C)C)(C(C)C)n1ccc2c(C(O)C3CCCN(Cc4ccccc4)C3)c(Cl)cnc21,,C1CCOC1,,[Li]CCCC,,test
US20080280925A1,N#Cc1cc(NN)cs1.O=C(CC(=O)C(F)(F)F)c1ccco1>>N#Cc1cc(-n2nc(C(F)(F)F)cc2-c2ccco2)cs1,,CC(=O)O,,Cc1ccccc1,Cl,test
US20100105740A1,COc1cc(CNC(C)=O)c(Br)cc1OCC(O)CO.Cl>>COc1cc(CN)c(Br)cc1OCC(O)CO.Cl,,CCO,,,,test
US20140336165A1,CC1(C)OB(/C=C/c2cc(F)cc(F)c2)OC1(C)C.Clc1cc2c(nn1)Oc1ccccc1O2>>Fc1cc(F)cc(/C=C/c2cc3c(nn2)Oc2ccccc2O3)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20040082590A1,CC(C)(C)OC(=O)N1CCN(c2ccccc2O)CC1.O=C(OCc1ccccc1)N1CCC[C@H](O)C1>>CC(C)(C)OC(=O)N1CCN(c2ccccc2OC2CCCN(C(=O)OCc3ccccc3)C2)CC1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130085131A1,Cc1nc2cccc(F)c2cc1Br.O=C1CCC(=O)N1Br>>Fc1cccc2nc(CBr)c(Br)cc12,,CC(=O)O,O,,,test
US20130005574A1,COC(=O)c1nc(-c2ccc([Si](C)(C)C)cc2)c(F)c(N)c1OC.ClI>>COC(=O)c1nc(-c2ccc(I)cc2)c(F)c(N)c1OC,,ClCCCl,,,,test
US05286905,BrC(Br)(Br)Br.Cc1cc(C)cc(OCC(C)O)c1>>Cc1cc(C)cc(OCC(C)Br)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150108402A1,CCOc1ccc(-c2ccc(CCC=O)cc2)c(F)c1F>>CCOc1ccc(-c2ccc(CCCO)cc2)c(F)c1F,,O,,CCO,[BH4-].[Na+],test
US20130012485A1,N#CC1(c2cc(F)ccc2F)CCC(=O)CC1>>N#CC1(c2cc(F)ccc2F)CCC(O)CC1,,C1CCOC1,,[BH4-].[Na+],,test
US20040034015A1,CCOC(=O)N1CCc2c(c3cccc4c3n2C(C)(C)CN4C)C1>>CCOC(=O)N1CCC2C(C1)c1cccc3c1N2C(C)(C)CN3C,,O=C(O)C(F)(F)F,,[BH3-]C#N.[Na+],,test
US20150119390A1,OCc1cccc(C2=CCOCC2)c1>>OCc1cccc(C2CCOCC2)c1,[Pd],CCO,,,,test
US20120302540A1,CN1C(=O)C2(CCCN(C(=O)OC(C)(C)C)C2)C1c1ccc(F)cc1>>CN1C(=O)C2(CCCNC2)C1c1ccc(F)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040010037A1,CC1CN(C(=O)OC(C)(C)C)CCN1.N#Cc1ccc(F)cc1C(F)(F)F>>CC1CN(C(=O)OC(C)(C)C)CCN1c1ccc(C#N)c(C(F)(F)F)c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,,test
US04591636,COc1ccc(OC)c2c1C[C@@](O)(COC(C)=O)CC21SCCS1.O>>COc1ccc(OC)c2c1C[C@@](O)(COC(C)=O)CC2=O,,C1CCOC1,CO,CCOCC,,test
US20100249139A1,CCOC(=O)c1ccc(COc2ccc(C(C)C(O)(c3cnc(C)cn3)C(F)(F)F)c(Cl)c2)cc1>>Cc1cnc(C(O)(C(C)c2ccc(OCc3ccc(C(=O)O)cc3)cc2Cl)C(F)(F)F)cn1,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20040092582A1,COc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)Cl)cc1)=NC(C)(C)C2.Cl.Nc1ccncc1>>COc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)Nc3ccncc3)cc1)=NC(C)(C)C2.Cl.Cl,,CN(C)C=O,,CCN(CC)CC,O=C([O-])O.[Na+],test
US04081477,CC1C(C(=O)O)CC2CC1C2(C)C.O=S(Cl)Cl>>CC1C(C(=O)Cl)CC2CC1C2(C)C,,CO,,,,test
US20030208079A1,CC(=O)Cl.COc1ccc2c(c1)COC2(C)C(F)(F)F>>COc1cc2c(cc1C(C)=O)C(C)(C(F)(F)F)OC2,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120270875A1,COC(=O)c1cnc(Cl)nc1C(F)(F)F.COc1ccccc1CCCN>>COC(=O)c1cnc(NCCCc2cccc(OC)c2)nc1C(F)(F)F,,CO,,CC(=O)[O-].[K+],,test
US04439425,CCCCCCCCCCCCCCCCC(CSC[C@H](NC(=O)CCCCCCCCCCCCCCC)C(=O)OC(c1ccccc1)c1ccccc1)OC(=O)CCCCCCCCCCCCCCC.O=C(O)C(F)(F)F>>CCCCCCCCCCCCCCCCC(CSC[C@H](NOC(=O)CCCCCCCCCCCCCCC)C(=O)O)OC(=O)CCCCCCCCCCCCCCC,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110144056A1,CC(C)(C)OC(=O)C1CC1c1ccc(-c2nn(C3CC3)cc2I)cn1.Sc1ccc(Cl)cc1>>CC(C)(C)OC(=O)C1CC1c1ccc(-c2nn(C3CC3)cc2Sc2ccc(Cl)cc2)cn1,[Cu]I,CCOC(C)=O,CN1CCCC1=O,[H-].[Na+],,test
US06388146B1,CCCCCC[C@@H](C)Oc1ccc(-c2ccc(O)cc2)cc1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCCCCC[C@@H](C)Oc1ccc(-c2ccc(OS(=O)(=O)C(F)(F)F)cc2)cc1,,O,,c1ccncc1,,test
US06277858B1,CCCCC(=Nc1sccc1C(=O)NCCC)OC.O=C1CCC(=O)N1Cl>>CCCCC(=Nc1sc(Cl)cc1C(=O)NCCC)OC,,c1ccncc1,,,,test
US20050282842A1,CSc1cccc2c(-c3ccnc(NC4CCCC4)n3)c(CC(C)C)nn12.O=C(OO)c1cccc(Cl)c1>>CC(C)Cc1nn2c(S(C)=O)cccc2c1-c1ccnc(NC2CCCC2)n1,,ClCCl,,O=C([O-])O.[Na+],,test
US05962462,C=CC[C@H](C(=O)N(C)OC)c1ccc(Cl)c(Cl)c1.[Li]C>>C=CC[C@H](C(C)=O)c1ccc(Cl)c(Cl)c1,,C1CCOC1,,,,test
US20110319380A1,CC1Cn2c(nc3cc(Br)ccc3c2=O)CN1C(=O)OCC1c2ccccc2-c2ccccc21>>CC1Cn2c(nc3cc(Br)ccc3c2=O)CN1,,ClCCl,O,C1CCNCC1,,test
US06204277B1,COC(=O)CC(=O)OC(C)(C)C.Cc1oc(-c2ccccc2)nc1CCOc1ccccc1C=O>>COC(=O)C(=Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)OC(C)(C)C,,Cc1ccccc1,,C1CCNCC1,CC(=O)O,test
US20150291531A1,COc1cc2cc(Br)ccc2[nH]c1=O.OB(O)c1ccc(F)cc1>>COc1cc2cc(-c3ccc(F)cc3)ccc2[nH]c1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20140275083A1,CC(F)(F)c1ccc(/C=N/[S@](=O)C(C)(C)C)c(F)c1.C[Mg]Br>>C[C@H](NS(=O)C(C)(C)C)c1ccc(C(C)(F)F)cc1F,,ClCCl,,,,test
US05756510,BrCCCCCBr.NC(=O)c1cccc(O)c1>>NC(=O)c1cccc(OCCCCCBr)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060287298A1,CCOC(=O)N=NC(=O)OCC.COC(=O)C1CCCCN1CCC(O)c1ccccc1.Oc1ccc(Cl)cc1>>CCOC(=O)C1CCCCN1CCC(Oc1ccc(Cl)cc1)c1ccccc1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04851539,CC[C@H]1CN2CC[C@H]1C[C@H]2[C@H](O)c1ccnc2ccc(OC)cc12.Fc1cc(Cl)cnc1F.O>>Oc1ccc(Oc2ncc(Cl)cc2F)cc1,,CS(C)=O,,[Na+].[OH-],,test
US20080200669A1,Nc1ccccc1.O=Cc1ccc(Br)cc1O>>Oc1cc(Br)ccc1/C=N/c1ccccc1,,CC(C)O,,,,test
US05723497,CCCCCCCCCCC(O)C1CO1.NCc1ccccc1>>CCCCCCCCCCC(O)C(O)CNCc1ccccc1,,C1COCCO1,,,,test
US20100029650A1,CSCc1ccc(-c2ccc(OCC3CCN(C(=O)OC(C)C)CC3)cn2)cc1.O=S([O-])OO>>CC(C)OC(=O)N1CCC(COc2ccc(-c3ccc(CS(C)(=O)=O)cc3)nc2)CC1,,CC(C)=O,,O,,test
US04382143,CCCCCCCCCCCCCCCC(=O)Cl.CCOC(=O)c1ccc(N)o1>>CCCCCCCCCCCCCCCC(=O)Nc1ccc(C(=O)OCC)o1,,ClCCl,,CCN(CC)CC,,test
US20120252801A1,CC1(C)OC1(C)C.CCN>>CCNC(C)(C)C(C)(C)O,,CO,O,,,test
US20130281433A1,COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccc4c(n3)c(N3CCN(C)CC3)nn4C)sc2c1-c1ccc(Cl)cc1>>Cc1cc2nc(-c3ccc4c(n3)c(N3CCN(C)CC3)nn4C)sc2c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US05457099,O=C(O)/C=C\C(=O)O.O=c1cc(CCN2CCC(c3c[nH]c4ccccc34)CC2)c2ccccc2[nH]1>>O=C(O)/C=C\C(=O)O.O=c1cc(CCN2CCC(c3c[nH]c4ccccc34)CC2)c2ccccc2[nH]1,,C1CCOC1,CO,,,test
US08895691B2,CC(=O)Oc1cc(C(=O)Cl)cc(C(=O)Cl)c1.CC(O)/C=C/C(C)O.O=C(Cl)c1cccc(C(=O)Cl)c1>>CC(O)/C=C/C(C)O.O=C(Cl)c1cc(O)cc(C(=O)Cl)c1.O=C(Cl)c1cccc(C(=O)Cl)c1,,C1CCOC1,,N,,test
US20060135554A1,N#Cc1ccc(NCC2CC2)c(N)c1.O=C(O)Cc1ccc(OCc2ccccc2)cn1>>N#Cc1ccc2c(c1)nc(Cc1ccc(OCc3ccccc3)cn1)n2CC1CC1,,CC(=O)O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20160207926A1,CC(C)(C)OC(=O)N[C@H]1CCN(C(=O)C2CC2)C1.Cl>>Cl.N[C@H]1CCN(C(=O)C2CC2)C1,,C1COCCO1,Cl,ClCCl,,test
US20160016908A1,COc1cccnc1N[C@H]1c2ccccc2N(C(C)=O)[C@@H](C2CC2)[C@@H]1C>>CC(=O)N1c2ccccc2[C@H](Nc2ncccc2O)[C@@H](C)[C@@H]1C1CC1,,CO,ClCCl,BrB(Br)Br,,test
US20070161638A1,CC(C)S(=O)(=O)N[C@H]1Cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C1.Cc1cncc(OS(=O)(=O)C(F)(F)F)c1>>Cc1cncc(-c2ccc3c(c2)C[C@@H](NS(=O)(=O)C(C)C)C3)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20140099283A1,CC(C)(CCN)C(=O)O.CCOC(=O)Cl>>CCOC(=O)NCCC(C)(C)C(=O)O,,O,,Cl,[Na+].[OH-],test
US05854277,O=C(O)CCBr.OCc1ccccc1>>O=C(CCBr)OCc1ccccc1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05215972,CC(C)CCC[C@@H](C)[C@H]1CCC2C3CC=C4CC(OC(=O)Cl)CC[C@]4(C)C3CC[C@@]21C.NC(CO)CO>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(=O)NC(CO)CO)CC[C@]4(C)[C@H]3CC[C@]12C,,CO,ClCCl,CCN(CC)CC,Cl,test
US05324747,CCCCCCCCCCN(CCCCCCCCCC)C(=O)c1cccc([N+](=O)[O-])c1>>CCCCCCCCCCN(CCCCCCCCCC)C(=O)c1cccc(N)c1,[Pd],C1CCOC1,CCOC(C)=O,[H][H],,test
US05610158,O=C(OC1Oc2ccccc2-n2cnc(-c3noc(C4CC4)n3)c21)c1ccccc1>>OC1Oc2ccccc2-n2cnc(-c3noc(C4CC4)n3)c21,,CO,,C[O-].[Na+],,test
US20060094749A1,Cc1ncc(CNC(=O)c2ccc(-c3ccc(NO)nc3)cc2)c2c1OC(C)(C)OC2>>Cc1ncc(CNC(=O)c2ccc(-c3ccc(N)nc3)cc2)c2c1OC(C)(C)OC2,[Pd],CCOC(C)=O,,,,test
US20040110757A1,COC(=O)c1ccc(COc2cc(-c3ccc(N4C(=O)c5ccc(C(=O)O)cc5C4=O)cc3)nc(-c3ccccc3)n2)cc1>>O=C(O)c1ccc(COc2cc(-c3ccc(N4C(=O)c5ccc(C(=O)O)cc5C4=O)cc3)nc(-c3ccccc3)n2)cc1,,C1CCOC1,,Cl,[K+].[OH-],test
US20040106667A1,Nc1ccc2[nH]nc(N)c2c1.O=S(=O)(Cl)c1cc(F)cc(F)c1>>Nc1n[nH]c2ccc(NS(=O)(=O)c3cc(F)cc(F)c3)cc12,,C1CCOC1,,c1ccncc1,,test
US06018046,CC(C)(C)OC(=O)CBr.O=c1c(Cc2cccnc2)cn2c3cc(Br)ccc3c3cc(O)cc1c32>>CC(C)(C)OC(=O)COc1cc2c(=O)c(Cc3cccnc3)cn3c4cc(Br)ccc4c(c1)c23,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130053556A1,CN(CCC(O)c1ccccc1[N+](=O)[O-])C(c1ccccc1)(c1ccccc1)c1ccccc1.O=C(n1ccnc1)n1ccnc1>>CN(CCC(OC(=O)n1ccnc1)c1ccccc1[N+](=O)[O-])C(c1ccccc1)(c1ccccc1)c1ccccc1,,ClCCl,,,,test
US20020132796A1,CCCNC1(c2ccc(C#Cc3ccc(C(=O)OCC)cc3)cc2)CC1>>CCCNC1(c2ccc(C#Cc3ccc(C(=O)O)cc3)cc2)CC1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20030073841A1,CCCC(=O)O[C@@H]1[C@H](O)c2c(cc(OC)c3c(=O)c4cc5ccccc5cc4n(C)c23)OC1(C)C>>CCCC(=O)OC1=Cc2c(cc(OC)c3c(=O)c4cc5ccccc5cc4n(C)c23)OC1(C)C,Cl,ClCCl,,,,test
US06114358,CCOC(=O)c1cc(CCl)on1>>O=C(O)c1cc(CCl)on1,,CCO,,[K+].[OH-],,test
US20100311713A1,CCC(=O)Cl.c1ccc(C(c2ccccc2)N2CC(N3CCNCC3)C2)cc1>>CCC(=O)N1CCN(C2CN(C(c3ccccc3)c3ccccc3)C2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140288040A1,CC[C@@H](N[S@](=O)C(C)(C)C)c1ccc(Cl)c(Oc2ccncn2)c1F.Cl>>CC[C@@H](N)c1ccc(Cl)c(Oc2ccncn2)c1F.Cl,,CCOC(C)=O,,,,test
US20120115845A1,CCBr.NC(=O)c1cc(O)ccc1Cl>>CCOc1ccc(Cl)c(C(N)=O)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120202804A1,C[C@H]1OC[C@@](N)(c2ccccc2F)[C@@H]1C(O)C(F)(F)F.O=C(N=C=S)c1ccccc1>>C[C@H]1OC[C@@](NC(=S)NC(=O)c2ccccc2)(c2ccccc2F)[C@@H]1C(O)C(F)(F)F,,CCOC(C)=O,ClCCl,,,test
US20090198063A1,BrCC1OCCO1.O=c1ccc2ccncc2[nH]1>>O=c1ccc2ccncc2n1CC1OCCO1,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20150080549A1,CC(C)(C)OC(=O)CBr.CN(CC(=O)O)C(=O)OCC1c2ccccc2-c2ccccc21>>CN(CC(=O)OCC(=O)OC(C)(C)C)C(=O)OCC1c2ccccc2-c2ccccc21,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160221946A1,CN(C(=O)OC(C)(C)C)c1c[nH]c2cc(Br)ccc12.O=S(=O)(Cl)c1cccnc1>>CN(C(=O)OC(C)(C)C)c1cn(S(=O)(=O)c2cccnc2)c2cc(Br)ccc12,,C1CCOC1,,O,[H-].[Na+],test
US20140163002A1,CC(C)(C)[S@@](N)=O.O=Cc1c(F)ccc(Cl)c1F>>CC(C)(C)[S@](=O)/N=C/c1c(F)ccc(Cl)c1F,,CCOC(C)=O,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cccnc3Nc3cncc(C)c3)n2)cc1>>Cc1cncc(Nc2ncccc2-c2nc(C)nc(N)n2)c1,,O=C(O)C(F)(F)F,,,,test
US20070287686A1,Cc1cc(C)n(C)c(=O)n1.OCCCBr>>CC1=CC(C)N(C)C(=O)[NH+]1CCCO.[Br-],,CC#N,,,,test
US20030199440A1,CC(C)(C)OC(=O)CCNC(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1>>N=C(N)Nc1ncc(Cl)c2ccc(C(=O)NCCC(=O)O)cc12,,O=C(O)C(F)(F)F,,Cc1ccccc1,,test
US06054470,COc1ccc(CCl)cc1.Cc1cn[nH]c(=O)c1C#N>>COc1ccc(Cn2ncc(C)c(C#N)c2=O)cc1,,CN(C)C=O,O,CCOC(C)=O,[H-].[Na+],test
US04939159,CC(=O)OC(C)=O.Cc1ccnc(-c2ccc(F)cc2)c1N>>CC(=O)Nc1c(C)ccnc1-c1ccc(F)cc1,,O,,,,test
US20130005689A1,CCOC(C)=O.CN(C)C=O.O=Cc1c(Cl)cc(O)cc1Cl>>COCCOc1cc(Cl)c(C=O)c(Cl)c1,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20160200686A1,COc1ccc(CC(NC(=O)OC(C)(C)C)C(=O)O)cc1.Cl>>COc1ccc(CC(N)C(=O)O)cc1.Cl,,C1COCCO1,,N#N,,test
US20110009391A1,Brc1ccc(N2CCNCC2)cc1.O=C(Cl)OCc1ccccc1>>O=C(OCc1ccccc1)N1CCN(c2ccc(Br)cc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20140364432A1,C[C@@H]1CCCN[C@@H]1CNc1ncc(Cl)cn1.O=C(Cl)c1ccccc1OC(F)(F)F>>C[C@@H]1CCCN(C(=O)c2ccccc2OC(F)(F)F)[C@@H]1CNc1ncc(Cl)cn1,,ClCCl,,CC(C)NC(C)C,,test
US20150119385A1,COC(OC)c1ccc2c(n1)N(C(=O)Nc1ccc(C#N)cn1)CCCC2>>N#Cc1ccc(NC(=O)N2CCCCc3ccc(C=O)nc32)nc1,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20130102617A1,CCOC(=O)C(=CC1CCOCC1)c1ccc(S(=O)(=O)C2CC2)c(Br)c1.OB(O)C1CC1>>CCOC(=O)C(=CC1CCOCC1)c1ccc(S(=O)(=O)C2CC2)c(C2CC2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,Cc1ccccc1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20100240669A1,CC(C)(C)OC(=O)NC1(C(=O)NCc2ccc(Nc3ccc(Br)cc3C(F)(F)F)cn2)CC1.O=C(O)C(F)(F)F>>NC1(C(=O)NCc2ccc(Nc3ccc(Br)cc3C(F)(F)F)cn2)CC1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US06998415B2,CCOC(N)=O.O=C(c1ccccc1)C(O)c1ccccc1>>O=c1[nH]c(-c2ccccc2)c(-c2ccccc2)o1,,CC(C)=O,,O,,test
US20160068532A1,O=[N+]([O-])c1cc2c(cc1Br)c(Cl)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>Nc1cc2c(cc1Br)c(Cl)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1,[Pt],CO,ClCCl,,,test
US20130345218A1,Cc1ccc(S(=O)(=O)n2cc(-c3nc(N[C@@H]4CCC[C@H](NC(=O)OC(C)(C)C)C4)c(F)cc3C(F)(F)F)c3cc(F)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3nc(N[C@H]4CCC[C@@H](N)C4)c(F)cc3C(F)(F)F)c3cc(F)cnc32)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150344423A1,COC(=O)c1nn(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)c(CP(=O)(OC)OC)c1C.O=C1CCCCC1>>COC(=O)c1nn(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)c(CC2CCCCC2)c1C,,C1CCOC1,,[H-].[Na+],,test
US05493030,CCOC(=O)CC(O)/C(C)=C/Cc1c(OC)c(C)c2c(c1O[Si](C)(C)C(C)(C)C)C(=O)OC2.CI>>CCOC(=O)CC(OC)/C(C)=C/Cc1c(OC)c(C)c2c(c1O[Si](C)(C)C(C)(C)C)C(=O)OC2,O=[Ag],CC#N,,,,test
US20150210697A1,COc1ccc(CN(c2nc(Nc3cc(C#N)cc(N4CCOC(CO)C4)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1.CS(=O)(=O)Cl>>COc1ccc(CN(c2nc(Nc3cc(C#N)cc(N4CCOC(COS(C)(=O)=O)C4)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,O=C([O-])O.[Na+],test
US04288436,C=CCON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3CCC(=O)O)CS[C@H]12)c1csc(NC=O)n1>>C=CCON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3CCC(=O)O)CS[C@H]12)c1csc(N)n1,,CO,,Cl,,test
US03956315,CCC(C)c1csc(N)c1C#N.CN=C=O>>CCC(C)c1csc(NC(=O)NC)c1C#N,,COCCOC,,,,test
US20090118289A1,COC(=O)Cc1cc(O)cc(OCc2ccc(F)cc2)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)Cc1cc(OCc2ccc(F)cc2)cc(OS(=O)(=O)C(F)(F)F)c1,,ClCCl,,c1ccncc1,,test
US20070249580A1,BrCc1ccccc1.CC(C)(C)OC(=O)N1CCCC(C(=O)O)C1>>CC(C)(C)OC(=O)N1CCCC(C(=O)OCc2ccccc2)C1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150218170A1,Cc1nsc(Nc2cnc3c(n2)c(C(=O)NC(C)(C)C)cn3COCC[Si](C)(C)C)n1>>Cc1nsc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110183960A1,COC(=O)C1CNC1.O=C(Cl)OCc1ccccc1>>COC(=O)C1CN(C(=O)OCc2ccccc2)C1,,ClCCl,,CCN(CC)CC,Cl,test
US20050020660A1,CO[C@]1(C#CC(O)(c2ccccc2)C2CCN(C(=O)OC(C)(C)C)CC2)CN2CCC1CC2>>CO[C@]1(C#CC(O)(c2ccccc2)C2CCNCC2)CN2CCC1CC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070197537A1,Cn1c(Cl)ncc(Br)c1=O.Nc1ccccc1>>Cn1c(Nc2ccccc2)ncc(Br)c1=O,,CCCCO,CCOC(C)=O,O=C([O-])O.[Na+],,test
US20070232603A1,CC1CCC(C(C)C)C(C(=O)Cl)C1.COc1ccc(N)c([N+](=O)[O-])c1>>COc1ccc(NC(=O)C2CC(C)CCC2C(C)C)c([N+](=O)[O-])c1,,c1ccncc1,,Cl,ClCCl,test
US20050209274A1,CC(=O)c1ccc2[nH]c(=O)oc2c1.CCI>>CCn1c(=O)oc2cc(C(C)=O)ccc21,,CN(C)C=O,CO,O=C([O-])[O-].[K+].[K+],,test
US20110003786A1,COCOc1ccc(C(C)(OS(C)(=O)=O)C(F)(F)F)nc1.C[Al](C)C>>COCOc1ccc(C(C)(C)C(F)(F)F)nc1,,ClCCl,,O,,test
US05494925,CCCC1C(=O)N(CSc2ccccc2)S(=O)(=O)N1C.O=S(=O)(Cl)Cl>>CCCC1C(=O)N(CCl)S(=O)(=O)N1C,,ClCCl,,,,test
US20020187978A1,CI.O=C1Cc2c(cccc2C2CCNCC2)N1>>CN1CCC(c2cccc3c2CC(=O)N3)CC1,,CC#N,CO,,,test
US20080293708A1,CO.COC(=O)c1c([N+](=O)[O-])ccc(F)c1CCC(=O)O.O=C([O-])O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COC(=O)c1c([N+](=O)[O-])ccc(F)c1CC(N=C=O)OC,Cl[Cu]Cl,CO,O,CCN(CC)CC,,test
US20060116515A1,Cc1cc(C(C)NCCN(Cc2ccc3c(c2)OCO3)C(=O)OC(C)(C)C)nc(-n2ccnc2)n1>>Cc1cc(C(C)NCCNCc2ccc3c(c2)OCO3)nc(-n2ccnc2)n1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20140349991A1,CI.COCOc1ccc2c(O)c(C)c(=S)oc2c1C>>COCOc1ccc2c(=O)c(C)c(SC)oc2c1C,,CC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US06087364,CI.O=C(O)CC1NC(=O)c2ccccc21>>COC(=O)CC1NC(=O)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20090163488A1,CCn1nc(C)cc1C(=O)O.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)c1>>CCn1nc(C)cc1C(=O)Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)c1,CN(C)C=O,CC(=O)N(C)C,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US20070244125A1,BrCC1CC1.CC(C)N1CCN(C(=O)c2ccc3[nH]c(C(=O)N4CCS(=O)(=O)CC4)cc3c2)CC1>>CC(C)N1CCN(C(=O)c2ccc3c(c2)cc(C(=O)N2CCS(=O)(=O)CC2)n3CC2CC2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20080293771A1,COC(=O)c1ccc(F)cc1.Cc1nc2ccccc2[nH]1>>COC(=O)c1ccc(-n2c(C)nc3ccccc32)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050256201A1,CC(C)(C)[Si](C)(C)OCCCCc1cccc(N)c1.O=C=NC(=O)C(Cl)(Cl)Cl>>CC(C)(C)[Si](C)(C)OCCCCc1cccc(NC(N)=O)c1,,ClCCl,,[Na+].[OH-],,test
US20090163512A1,C=C(N=Cc1cc(F)ccc1C)O[Si](C)(C)C.CC(C)(C)OC(=O)N1CCN(c2ccc(Cl)cc2/C=C2\C(=O)N(C(=O)OC(C)(C)C)c3cc(Cl)ccc32)CC1>>Cc1ccc(F)cc1C1NC(=O)CC(c2cc(Cl)ccc2N2CCN(C(=O)OC(C)(C)C)CC2)C12C(=O)Nc1cc(Cl)ccc12,,Cc1ccccc1,,,,test
US20130052281A1,COC1CC=C(C#Cc2cc(OCc3ccccc3)c(OCc3ccccc3)nn2)CC1>>COC1CCC(CCc2cc(O)c(=O)[nH]n2)CC1,,CO,,,,test
US20040132727A1,CCCCN(CCN)CCCC.COc1cc2nccc(Oc3cc(C)c(N)cc3C)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCCCN(CCCC)CCNC(=O)Nc1cc(C)c(Oc2ccnc3cc(OC)c(OC)cc23)cc1C,,ClC(Cl)Cl,O,CCN(CC)CC,,test
US20130274258A1,Cc1nccc2c1[nH]c1ccc(Br)cc12.N#Cc1cccc(B(O)O)c1>>Cc1nccc2c1[nH]c1ccc(-c3cccc(C#N)c3)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20070078165A1,Cc1ccc(Br)cn1.OO>>Cc1ccc(Br)c[n+]1[O-],,CC(=O)O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20160166571A1,C=CC(=O)Cl.CN(C)CC1CN(c2ncnc3cc(Cl)c(-c4ccc(Cl)cc4)cc23)CCN1>>C=CC(=O)N1CCN(c2ncnc3cc(Cl)c(-c4ccc(Cl)cc4)cc23)CC1CN(C)C,,ClCCl,,CCN(CC)CC,,test
US20150152069A1,CC(=O)N1CCNCC1.CC(C)Oc1cc(F)ccc1[N+](=O)[O-]>>CC(=O)N1CCN(c2ccc([N+](=O)[O-])c(OC(C)C)c2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130035326A1,CS(=O)(=O)O.Cc1cc(-c2ccc(CC(=O)Nc3cc(C(C)(C)C)on3)cc2)cnc1N>>CS(=O)(=O)[O-].Cc1cc(-c2ccc(CC(=O)Nc3cc(C(C)(C)C)on3)cc2)cnc1[NH3+],,CCO,,,,test
US06936602B1,CCCOCCOc1ccc(OB([O-])[O-])cc1.COC(=O)C1=Cc2cc(Br)ccc2N(c2ccccc2)CC1>>CCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3c2ccccc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[K+].[K+],test
US20020099212A1,O=C(O)c1ccc(OCc2ccccc2)cc1Cl>>OCc1ccc(OCc2ccccc2)cc1Cl,,C1CCOC1,,Cl,O,test
US20100087424A1,O=c1ccc2ncc(F)c3c2n1C(CO)CC3>>O=CC1CCc2c(F)cnc3ccc(=O)n1c23,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20090042890A1,CCN(c1ccccc1O)N1CN=C(Nc2ccccc2OC)C=C1C(=O)[O-].CCOC(=O)c1nc(Nc2cccc(CO)c2)nc(Nc2ccccc2OC)c1N>>COc1ccccc1-n1c(=O)[nH]c2c(C(N)=O)nc(Nc3cccc(CO)c3)nc21,[Pd],,,CCO,,test
US20090198056A1,COC(=O)c1cc(N2CC(c3ccccc3)CC2=O)cc(N(C)S(C)(=O)=O)c1>>CN(c1cc(C(=O)O)cc(N2CCC(c3ccccc3)C2)c1)S(C)(=O)=O,,C1CCOC1,,CO,,test
US20120226036A1,CC(C)(C)OC(=O)CN(C(=O)OC(C)(C)C)c1cccc(C(NCc2ccc(-c3nccs3)cc2)S(=O)(=O)c2ccccn2)n1>>O=C(O)CNc1cccc(C(NCc2ccc(-c3nccs3)cc2)S(=O)(=O)c2ccccn2)n1,,ClCCl,,C1COCCO1,Cl,test
US20060264486A1,CCCc1cc(-c2nc3c(s2)CCCC3)ccc1OCCCOc1ccc2c(ccn2CC(=O)OC)c1>>CCCc1cc(-c2nc3c(s2)CCCC3)ccc1OCCCOc1ccc2c(ccn2CC(=O)O)c1,,C1CCOC1,O,[Li]O,,test
US20060079522A1,CC(=O)N(CCNC(=O)Nc1ccc(C)c(C2CCN(Cc3ccc(Oc4cc(F)c(F)cc4F)cc3)CC2)c1)OC(C)(C)C.Cl.ClCCl>>CNCCNC(=O)Nc1ccc(C)c(C2CCN(Cc3ccc(Oc4cc(F)c(F)cc4F)cc3)CC2)c1.Cl.Cl,,CO,ClCCl,O=C(O)C(F)(F)F,,test
US20060183939A1,O=C(O)c1ccccc1.Oc1ccccc1>>O=C(O)c1ccccc1O,,O,,O=C=O,,test
US20100069384A1,CC(C)(N)CF.CCOc1ccc2c(c1)C(C)(c1ccccc1Cl)C(=O)N2S(=O)(=O)c1ccc(C(=O)O)cc1>>CCOc1ccc2c(c1)C(C)(c1ccccc1Cl)C(=O)N2S(=O)(=O)c1ccc(C(=O)NC(C)(C)CF)cc1,,ClCCl,O,CCN(CC)CC,O=C1OCCN1P(=O)(Cl)N1CCOC1=O,test
US06184208B2,C[C@@H](N)C(=O)O.O=C(N[C@@H](Cc1ccccc1)C(=O)Oc1c(F)c(F)c(F)c(F)c1F)OCc1ccccc1>>C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)O,,C1CCOC1,O,,,test
US05194622,CI.COC(=O)C(=CO)c1ccccc1C>>CO/C=C(\C(=O)OC)c1ccccc1C,,C1CCOC1,,O,[H-].[Na+],test
US20110212945A1,COC(=O)c1cc(C2CC2)ccc1Nc1cnc(OCc2ccccc2)c(-c2ccccc2)c1>>O=C(O)c1cc(C2CC2)ccc1Nc1cnc(O)c(-c2ccccc2)c1,,O=C(O)C(F)(F)F,,,,test
US20080096874A1,COC(=O)C1(C)CCN(c2ccc([N+](=O)[O-])cn2)CC1>>COC(=O)C1(C)CCN(c2ccc(N)cn2)CC1,[Pd],C1CCOC1,,CCO,,test
US20160264548A1,CSc1ncc(C(N)=O)c(Cl)n1.Oc1ccc(Oc2ccccc2)cc1>>CSc1ncc(C(N)=O)c(Oc2ccc(Oc3ccccc3)cc2)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04237136,CCOC(=O)C#CC(=O)OCC.Cc1cnc(N)s1>>CCOC(=O)c1cc(=O)nc2sc(C)cn12,,CCO,,,,test
US20010053779A1,CC(C)(C)OC(=O)NCCBr.COc1ccccc1O>>COc1ccccc1OCCNC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US03987158,CC(CN)Oc1ccccc1.Cc1ccc(S(=O)(=O)O)cc1.N=C(N)Cc1ccccc1>>CC(CNC(=N)Cc1ccccc1)Oc1ccccc1.Cc1ccc(S(=O)(=O)O)cc1,,CCO,CCOCC,N,,test
US20090253687A1,CON(C)C(=O)Cc1ccc2c(c1)NC(=O)CO2.Cc1cc(F)ccc1[Mg]Br>>Cc1cc(F)ccc1C(=O)Cc1ccc2c(c1)NC(=O)CO2,,C1CCOC1,O,,,test
US20090143448A1,C#C[Si](C)(C)C.Cc1nc(NC(=O)OC(C)(C)C)sc1I>>Cc1nc(NC(=O)OC(C)(C)C)sc1C#C[Si](C)(C)C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,,CCN(CC)CC,[Cl-].[NH4+],test
US20070037881A1,COc1cc(C#N)ccc1F.Oc1ccc(Cl)cc1Cl>>COc1cc(C#N)ccc1Oc1ccc(Cl)cc1Cl,,CCOCC,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080114049A1,Cl.Clc1ccc([C@@]23CCNC[C@@H]2C3)cc1Cl>>Cl.Clc1ccc([C@@]23CCNC[C@@H]2C3)cc1Cl,,ClCCl,,,,test
US20160214943A1,CCOC(=O)c1cc(-c2ccc(Br)cc2)n(CC(C)C)n1.CS(=O)(=O)c1cccc(B(O)O)c1>>CCOC(=O)c1cc(-c2ccc(-c3cccc(S(C)(=O)=O)c3)cc2)n(CC(C)C)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US05100762,C=C(C)C(=O)O.CCCC[Sn](O)(CCCC)CCCC>>C=C(C)C(=O)O[Sn](CCCC)(CCCC)CCCC,,Cc1ccccc1C,,O,,test
US06235786B1,CC(CCS(=O)(=O)c1ccc(Oc2ccccc2)cc1)N(OC(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>CC(CCS(=O)(=O)c1ccc(Oc2ccccc2)cc1)NO,,ClCCl,,,,test
US20140336190A1,Cc1noc(C)c1-c1cc(C(=O)c2ccccn2)c2c(c1)nc(C1CC1)n2C.c1ccnnc1>>Cc1noc(C)c1-c1cc(C(O)(c2ccccn2)c2cccnn2)c2c(c1)nc(C1CC1)n2C,,C1CCOC1,,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US20110190297A1,Clc1cncc(Cl)c1Cl.O=C([O-])N1CCN(C(=O)c2ccccc2)CC1>>O=C(c1ccccc1)N1CCN(c2c(Cl)cncc2Cl)CC1,,CN1CCCC1=O,,CCN(CC)CC,,test
US20070281933A1,NC(=O)c1cc(-c2cccc(F)c2)cc2c(C3CCNCC3)n[nH]c12.O=S(=O)(Cl)CCCl.OC1CCNCC1>>NC(=O)c1cc(-c2cccc(F)c2)cc2c(C3CCN(S(=O)(=O)CCN4CCC(O)CC4)CC3)n[nH]c12,,CN(C)C=O,,CCN(CC)CC,O=C([O-])[O-].[K+].[K+],test
US05284951,O=[Se]=O.OCC(CO)c1nc2ccccc2c2ccccc12>>O=Cc1nc2ccccc2c2ccccc12,,CCOC(C)=O,,,,test
US20160009662A1,CC1(C)CC([O-])CC(C)(C)C1.COC(=O)C[C@H](c1cccc(OCc2cnc(-c3cc(OC)ccc3F)c(Cl)n2)c1)C1CC1>>COc1ccc(F)c(-c2ncc(COc3cccc([C@@H](CC(=O)O)C4CC4)c3)nc2OC2CC(C)(C)CC(C)(C)C2)c1,,C1CCOC1,,Cl,,test
US04051248,COc1ccc2c(c1)CC[C@H](CN1CCC3(CC1)C(=O)NCN3c1ccccc1)[C@@H]2O.Cl>>COc1ccc2c(c1)CC[C@H](CN1CCC3(CC1)C(=O)NCN3c1ccccc1)[C@@H]2O.Cl,,CCOCC,,,,test
US20090221583A1,CI.O=C(NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1)c1ccc(-c2ccccc2)cc1O>>COc1cc(-c2ccccc2)ccc1C(=O)NCC(=O)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090137804A1,CN1CCN(CCCCl)CC1.Nc1ccc(O)cc1>>CN1CCN(CCCOc2ccc(N)cc2)CC1,,CN(C)C=O,,Cl,[Na+].[OH-],test
US04579845,CCC(C)N.CSC(=N)N(C#N)CC1CCN(CC2COc3ccccc3O2)CC1>>CCC(C)NC(=N)N(C#N)CC1CCN(CC2COc3ccccc3O2)CC1,,c1ccncc1,,,,test
US20150158857A1,COc1ccc([C@@H](O)Cc2c(Cl)c[n+]([O-])cc2Cl)cc1OC.O=C(N[C@@H](c1ccccc1)c1cccc(OCc2ccc(C(=O)O)cc2)c1)O[C@H]1CN2CCC1CC2>>COc1ccc([C@H](Cc2c(Cl)c[n+]([O-])cc2Cl)OC(=O)c2ccc(COc3cccc([C@@H](NC(=O)O[C@H]4CN5CCC4CC5)c4ccccc4)c3)cc2)cc1OC,CN(C)c1ccncc1,CN(C)C=O,,CCN=C=NCCCN(C)C,Cl,test
US20100113465A1,CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)C2.Fc1ccc(Br)cc1Cl>>CC(C)(C)OC(=O)N1CCC2(CC1)CC(O)(c1ccc(F)c(Cl)c1)C2,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20070054923A1,CCOC(=O)CC(=O)OCC.Cc1ccc2c(c1)c(=O)oc(=O)n2Cc1ccccc1>>CCOC(=O)c1c(O)c2cc(C)ccc2n(Cc2ccccc2)c1=O,,CC(=O)N(C)C,,[H][H],[H-].[Na+],test
US20030212111A1,CC(C)(C)OC(=O)c1ccc(Cl)c([N+](=O)[O-])c1.CCN>>CCNc1ccc(C(=O)OC(C)(C)C)cc1[N+](=O)[O-],,C1CCOC1,,,,test
US20120149691A1,C[C@@H]1CCCC[C@@H]1Nc1c(C#N)cnn2cccc12.OO>>C[C@@H]1CCCC[C@@H]1Nc1c(C(N)=O)cnn2cccc12,,CCO,,[NH4+].[OH-],,test
US20030120069A1,C=CCOC(=O)N1C[C@H](O)C[C@H]1CO.CC(C)(C)[Si](C)(C)Cl>>C=CCOC(=O)N1C[C@H](O)C[C@H]1CO[Si](C)(C)C(C)(C)C,,CCOC(C)=O,ClCCl,C1CCC2=NCCCN2CC1,,test
US20050059687A1,CC(Br)c1nc2ccccc2c(=O)[nH]1.COc1ccc(S(=O)(=O)N2CCNCC2)cc1>>COc1ccc(S(=O)(=O)N2CCN(C(C)c3nc4ccccc4c(=O)[nH]3)CC2)cc1,,CC#N,,,,test
US20110263559A1,CSc1nn(-c2ccccc2)c2cc(N3CCN(C(=O)OC(C)(C)C)CC3)ccc12.Cl>>CSc1nn(-c2ccccc2)c2cc(N3CCNCC3)ccc12.Cl,,ClCCl,,,,test
US20140315886A1,COc1ccc(NC(=O)c2cccnc2)c(C(N)=O)c1>>COc1ccc2nc(-c3cccnc3)nc(O)c2c1,,CCO,,[Na+].[OH-],,test
US20140051672A1,CC(C)(C)OC(=O)N1CCC(O)CC1.COc1cc(-n2cccn2)ccc1-c1ccc(Cl)nn1>>COc1cc(-n2cccn2)ccc1-c1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)nn1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20030073707A1,COC(C)(OC)OC.Nc1ccc(C(=O)O)cc1O>>Cc1nc2ccc(C(=O)O)cc2o1,,CO,,,,test
US20040102481A1,COc1cc(C)c2[nH]cc(C3CCN(C)CC3)c2c1>>Cc1cc(O)cc2c(C3CCN(C)CC3)c[nH]c12,,O,,Cl,c1ccncc1,test
US06855715B1,COc1ccc(C(=O)N[C@@H](CNC(=O)C2CCN(C(=O)OC(C)(C)C)CC2)c2ccccc2)cc1.O=C(O)C(F)(F)F>>COc1ccc(C(=O)N[C@@H](CNC(=O)C2CCNCC2)c2ccccc2)cc1.O=C(O)C(F)(F)F,,ClCCl,,COc1ccccc1,,test
US20050070441A1,CC(C)N=C=O.Cc1[nH]nc(Oc2ncc(C(F)(F)F)cc2Cl)c1C>>Cc1c(Oc2ncc(C(F)(F)F)cc2Cl)nn(C(=O)NC(C)C)c1C,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US06573260B1,CCOC(=O)CC(=O)[C@@H](NC(=O)OCc1ccccc1)C1CC1>>CCOC(=O)CC(O)[C@@H](NC(=O)OCc1ccccc1)C1CC1,,CCO,,O,[BH4-].[Na+],test
US20090291917A1,CCOC(=O)COc1cc(C#N)ccc1Oc1ccc2c(c1)COB2O>>N#Cc1ccc(Oc2ccc3c(c2)COB3O)c(OCC(=O)O)c1,,CO,,Cl,[Na+].[OH-],test
US20080269294A1,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(C2CCNCC2)cc1.CCc1n[nH]cc1C=O>>CCc1n[nH]cc1CN1CCC(c2ccc(C(=O)Nc3ccccc3N)cc2)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20040167176A1,Brc1ccc(Cn2ccnc2)cc1.CCCCc1cc(B(O)O)c(S(=O)(=O)NC(C)(C)C)s1>>CCCCc1cc(-c2ccc(Cn3ccnc3)cc2)c(S(=O)(=O)NC(C)(C)C)s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,CCOC(C)=O,Cc1ccccc1,[Na+].[OH-],test
US20110237517A1,COC(=O)N1CC(c2c[nH]c3cc(F)ccc23)C2C1CCN2C(=O)C(NC(=O)OC(C)(C)C)C1CCCCC1.O=C(Cl)c1ccccc1>>CC(C)(C)OC(=O)NC(C(=O)N1CCC2C1C(c1c[nH]c3cc(F)ccc13)CN2C(=O)c1ccccc1)C1CCCCC1,,ClCCl,,,,test
US20020019401A1,Nc1ccc(F)cc1NC1CC2CC(=O)CC2C1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=C1CC2CC(n3c(=O)[nH]c4ccccc43)CC2C1,,ClCCl,,CCN(CC)CC,,test
US20070259888A1,CC(C)(C)OC(=O)N1CCCC(CO)C1.CCI>>CCOCC1CCCN(C(=O)OC(C)(C)C)C1,,CN(C)C=O,,[H-].[Na+],,test
US20070032478A1,CCN(CC)CC(O)COc1ccc([N+](=O)[O-])cc1>>CCN(CC)CC(O)COc1ccc(N)cc1,[Ni],CCO,,NN,O,test
US20090088459A1,NCc1ccc(Br)s1.O=S(=O)(Cl)c1cccc(Cl)c1>>O=S(=O)(NCc1ccc(Br)s1)c1cccc(Cl)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04727180,COc1cc(C(O)(C(F)(F)F)C(F)(F)F)ccc1C=O.O=C(O)CC(=O)O>>COc1cc(C(O)(C(F)(F)F)C(F)(F)F)ccc1C=CC(=O)O,,c1ccncc1,,C1CCNCC1,,test
US20070225267A1,CN(C)C=O.Fc1cc(Br)cc(OCc2ccccc2)c1>>O=Cc1cc(F)cc(OCc2ccccc2)c1,,C1CCOC1,,[Li]CCCC,,test
US20090088463A1,Cc1cc(Cl)ccc1N.O=c1c2ccnn2c(=O)c2ccnn12>>Cc1cc(Cl)ccc1NC(=O)c1cc[nH]n1,,c1ccncc1,,CN(C)C=O,,test
US20080033002A1,CC(C)(C)OC(=O)N1CCC2(CCC(=O)c3ccccc32)CC1.O=S(=O)(N(c1ccccn1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCC2(CC=C(OS(=O)(=O)C(F)(F)F)c3ccccc32)CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04440788,CCN.CCSC[C@H](NC(=O)OC(C)(C)C)C(=O)O>>CCNC(=O)[C@H](CSCC)NC(=O)OC(C)(C)C,,C1CCOC1,CCOC(C)=O,CC(C)COC(=O)Cl,CCN(CC)CC,test
US20100261719A1,C[C@H]1CNC[C@@H](C)O1.O=C(O)c1ccc(F)c(F)c1F>>C[C@H]1CN(c2c(C(=O)O)ccc(F)c2F)C[C@@H](C)O1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05539112,Cc1c(F)c(NC(=O)C(C)(C)C)c2c(=O)cc(-c3ccc(NC(=O)C(C)(C)C)c(F)c3)oc2c1F>>Cc1c(F)c(N)c2c(=O)cc(-c3ccc(N)c(F)c3)oc2c1F,,C1COCCO1,,Cl,,test
US20100273770A1,CCOC(=O)CC1c2cccc(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)c2OCCN1C>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3OCCN(C)C4CC(=O)O)no2)cc1Cl,,CCO,,[Na+].[OH-],,test
US05164383,CCCSP(=O)(Cl)Cl.N.OC1CC(F)(F)C(F)(F)C1(F)F>>CCCSP(N)(=O)OC1CC(F)(F)C(F)(F)C1(F)F,,CCCCCC,ClCCl,CCN(CC)CC,,test
US06087304,COC(=O)c1ccc2cc(O)ccc2c1.ClCCN1CCOCC1>>COC(=O)c1ccc2cc(OCCN3CCOCC3)ccc2c1,,CN(C)C=O,,C[O-].[Na+],,test
US20100256387A1,CCCCCc1ccc(C(=O)NN)cc1.CCSc1ccccc1C(=O)Cl>>CCCCCc1ccc(C(=O)NNC(=O)c2ccccc2SCC)cc1,,ClCCl,,CCN(CC)CC,,test
US20150099719A1,COC(=O)[C@@H]1CCCC[C@H]1c1oc(N2CCC(F)(F)CC2)nc1-c1ccc(N2CCS(=O)(=O)CC2)cc1>>O=C(O)[C@@H]1CCCC[C@H]1c1oc(N2CCC(F)(F)CC2)nc1-c1ccc(N2CCS(=O)(=O)CC2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20110245308A1,COC(=O)c1ccc(CBr)cc1.O=c1[nH]nc(-c2ccc(Cl)cc2)n1CC(O)C(F)(F)F>>COC(=O)c1ccc(Cn2nc(-c3ccc(Cl)cc3)n(CC(O)C(F)(F)F)c2=O)cc1,,CC(C)=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04283532,CN(C)C(=O)Cc1ccccc1Br.Nc1c(Cl)cccc1Cl>>CN(C)C(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl,[Cu],Cc1ccccc1C,O,[I-].[K+],O=C([O-])O.[Na+],test
US20160229843A1,COc1cncc(-c2ccc(N)c(O)c2)c1.FC(F)(F)c1cnc(C2CC2)[nH]1>>COc1cncc(-c2ccc3nc(-c4cnc(C5CC5)[nH]4)oc3c2)c1,,CO,,[Na+].[OH-],,test
US05041673,Cl.N[C@@H]1Cc2ccc3ccccc3c2[C@@H](Cl)[C@H]1O>>Cl.N[C@@H]1Cc2ccc3ccccc3c2C[C@H]1O,[Pd],CO,,,,test
US05258529,C=C(Cl)CCl.CCCCCCCO>>C=C(Cl)CC(O)CCCCCC,[Zn],O,,Cc1ccccc1,,test
US20090054475A1,CC(C)(C)OC(=O)N1CCC(F)(c2ncc(COc3ccc(S(C)(=O)=O)cc3)s2)CC1.Cl>>CS(=O)(=O)c1ccc(OCc2cnc(C3(F)CCNCC3)s2)cc1.Cl,,C1COCCO1,CO,,,test
US20100216794A1,COCCOc1cc(Oc2cccnc2)cnc1NC(N)=S.O=CCCl>>COCCOc1cc(Oc2cccnc2)cnc1Nc1nccs1,,CN(C)C=O,,,,test
US20110144105A1,CC(C)C=C(c1cccc(-n2cccn2)c1)c1cc2cccnc2n1S(=O)(=O)c1ccccc1>>CC(C)C=C(c1cccc(-n2cccn2)c1)c1cc2cccnc2[nH]1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20140187545A1,CCOC(=O)CC(=O)c1ccncc1.COc1[nH]nc(N)c1Cc1cccc(Cl)c1Cl>>COc1nn2c(O)cc(-c3ccncc3)nc2c1Cc1cccc(Cl)c1Cl,,CC(=O)O,,,,test
US03991076,C1=C(N2CCCC2)CCSC1.O.O=C(CBr)c1cccc(C(F)(F)F)c1>>O=C(CC1CSCCC1=O)c1cccc(C(F)(F)F)c1,,O,,CN(C)C=O,,test
US08796474B1,CCCCC(O)(CCCC)C(=O)C(Br)CC(C)C>>CCCCC1(CCCC)OC(CC(C)C)C1=O,,CS(C)=O,O,[K+].[OH-],,test
US20130090442A1,C=C(C)C(=O)Cl.C=C(C)C(=O)O>>C=C(C)C(=O)OC(=O)C(=C)C,,C1CCOC1,,CCN(CC)CC,,test
US20100105659A1,CC(C)(C)OC(=O)N1CCC(c2nsc(Nc3ncc(Oc4ccc(C=O)cc4)cc3Sc3ccccc3Cl)n2)CC1>>O=Cc1ccc(Oc2cnc(Nc3nc(C4CCNCC4)ns3)c(Sc3ccccc3Cl)c2)cc1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US05071859,CCO.Cl.ClCCl.O=C(O)C1=CCCN(CCOC=C(c2cccc(F)c2)c2cccc(F)c2)C1>>COc1cccc(C(=COCCN2CCC=C(C(=O)O)C2)c2ccccc2C)c1.Cl,,O,,Cl,[Na+].[OH-],test
US20060041137A1,CCC(=O)Cl.CCCC1=NNC(=O)/C1=C1/C=C(Sc2ccc(N)cc2)c2ccccc2N1>>CCCC1=NNC(=O)/C1=C1/C=C(Sc2ccc(NC(=O)CC)cc2)c2ccccc2N1,,C1CCOC1,,,,test
US04920120,C1CNCCN1.CCn1cc(C(=O)O)c(=O)c2c(C)c(F)c(F)c(F)c21>>CCn1cc(C(=O)O)c(=O)c2c(C)c(F)c(N3CCNCC3)c(F)c21,,CC#N,,,,test
US20080255122A1,CCCCN1C(=O)C(Cl)=C(c2ccc(Cl)cc2)S1(=O)=O.Nc1ccc(OC(F)F)cc1>>CCCCN1C(=O)C(Nc2ccc(OC(F)F)cc2)=C(c2ccc(Cl)cc2)S1(=O)=O,,CC#N,,,,test
US20100105655A1,CC(=O)OC(C)=O.COc1cc(OC[C@H]2CCCN2)ccc1Nc1ncc(OC)c(-c2cnc3ccccn23)n1>>COc1cc(OC[C@H]2CCCN2C(C)=O)ccc1Nc1ncc(OC)c(-c2cnc3ccccn23)n1,,ClCCl,,,,test
US20100160373A1,CN1C(=O)COc2ccc([N+](=O)[O-])cc21>>CN1C(=O)COc2ccc(N)cc21,[Fe],CCO,O,,,test
US20100099712A1,CCOC(=O)C1=NN(c2ccc(Cl)cc2Cl)[C@@H](C)[C@@H]1c1ccccc1>>C[C@H]1[C@H](c2ccccc2)C(C(=O)O)=NN1c1ccc(Cl)cc1Cl,,CO,,[Na+].[OH-],,test
US20120101100A1,CCNC(=O)Nc1cc(-c2nc(-c3ccccn3)cs2)c(Br)cn1.CCOC(=O)c1cncc(B2OC(C)(C)C(C)(C)O2)c1>>CCNC(=O)Nc1cc(-c2nc(-c3ccccn3)cs2)c(-c2cncc(C(=O)OCC)c2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060287287A1,COc1ccc(-c2noc(C)c2C(=O)O)cc1.CSC(=N)NC(=O)OC(C)(C)C>>COc1ccc(-c2noc(C)c2C(=O)N(C(=N)SC)C(=O)OC(C)(C)C)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CCN=C=NCCCN(C)C,test
US05244908,CS(=O)(=O)NCCCOS(C)(=O)=O.Sc1cccc2nccn12>>CS(=O)(=O)NCCCSc1cccc2nccn12,,CCO,,C[O-].[Na+],,test
US20160137649A1,BrCc1ccccc1.Cn1cc(CN2CC3CN(C(=O)OC(C)(C)C)CC3C2)c(-c2ccncc2)n1>>Cn1cc(CN2CC3CN(C(=O)OC(C)(C)C)CC3C2)c(-c2cc[n+](Cc3ccccc3)cc2)n1.[Br-],,CC(C)=O,,,,test
US20040082619A1,CCCCn1cc2c(c(C#N)c1=O)CCCC2O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCCCn1cc2c(c(C#N)c1=S)CCCC2,,Cc1ccccc1,,CO,,test
US20030212113A1,CCCBr.O=C(O)c1ccc2[nH]c(C(=O)O)cc2c1>>CCCn1c(C(=O)O)cc2cc(C(=O)O)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20090004396A1,CCO.O=C1C=CC(=O)O1.OCCO.Oc1ccc(O)cc1>>C=CCOCC(CC)(CO)CO.CC(O)CO,,CCO,,,,test
US20030125371A1,CCOC(=O)C(=O)c1cn(Cc2ccccc2)c2cccc(-c3ccc(C(F)(F)F)cc3)c12>>O=C(O)C(=O)c1cn(Cc2ccccc2)c2cccc(-c3ccc(C(F)(F)F)cc3)c12,,C1CCOC1,O,[K+].[OH-],,test
US03956260,COC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](COC(C)(C)C)NC(=O)OCc1ccccc1>>COC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)COC(C)(C)C,[Pd],CO,,,,test
US20080085890A1,COCC(C)=O.O=C1NC(=O)c2ccc(I)cc2/C1=C/Nc1ccc(N2CCNCC2)cc1>>COCC(C)N1CCN(c2ccc(N/C=C3\C(=O)NC(=O)c4ccc(I)cc43)cc2)CC1,,CN1CCCC1=O,ClCCl,CC(=O)O,O=C([O-])O.[Na+],test
US06511974B1,O=C(Cl)c1ccc(-n2cccn2)cc1.c1ccc2c(c1)Cn1cccc1CN2>>O=C(c1ccc(-n2cccn2)cc1)N1Cc2cccn2Cc2ccccc21,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040087621A1,CC(C)(C)OC(=O)NC[C@H](CN1CCC(Oc2ccc(F)cc2)CC1)NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NC[C@@H](N)CN1CCC(Oc2ccc(F)cc2)CC1,[Pd],CO,,O=C[O-].[NH4+],,test
US20120122888A1,Cc1cc(C(C#N)C#N)ccc1Cl.NN>>Cc1cc(-c2c(N)n[nH]c2N)ccc1Cl,,ClC(Cl)Cl,,O,,test
US20080207654A1,CCCCc1nc(C)n(-c2ccc(F)c(C)c2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nc(C)n(-c2ccc(F)c(C)c2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US05087638,C=CCBr.COc1ccc(Cc2oc3c(Cl)ccc(O)c3c2C)cc1>>C=CCOc1ccc(Cl)c2oc(Cc3ccc(OC)cc3)c(C)c12,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120071505A1,CC1OCCC1Sc1c(I)cnc2ccccc12.COc1ccc(B(O)O)cc1>>COc1ccc(-c2cnc3ccccc3c2SC2CCOC2C)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US04847289,COCCOCOC(CCS(=O)(=O)c1ccc(S(N)(=O)=O)s1)c1ccccc1>>NS(=O)(=O)c1ccc(S(=O)(=O)CCC(O)c2ccccc2)s1,,CO,O,O=S(=O)(O)O,,test
US20110224241A1,CC(C)(C)OC(=O)c1c(-c2ccc(Cl)cc2)nsc1-c1ccccc1>>O=C(O)c1c(-c2ccc(Cl)cc2)nsc1-c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070155808A1,COC(=O)CCc1ccc(O)cc1.OCc1ccc(CN(CCc2ccccc2)c2nc(-c3ccccc3)cs2)cc1>>COC(=O)CCc1ccc(OCc2ccc(CN(CCc3ccccc3)c3nc(-c4ccccc4)cs3)cc2)cc1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20050119320A1,CC(=O)C(Br)c1ccc(F)c(S(C)(=O)=O)c1.CC(=O)NC(N)=S>>CC(=O)Nc1nc(C)c(-c2ccc(F)c(S(C)(=O)=O)c2)s1,,CCO,,CCOC(C)=O,O,test
US05686424,COc1cc(C(=O)CC(NC(=O)[C@@H]2CCCN2)(c2ccccc2)c2ccccc2)cc(OC)c1OC.Cl>>COc1cc(C(=O)CC(NC(=O)[C@@H]2CCCN2)(c2ccccc2)c2ccccc2)cc(OC)c1OC.Cl,,CCOCC,,,,test
US05155099,CC(C)c1ccc(S(=O)(=O)Cl)c(C(C)C)c1C(C)C.N[C@@H](CO)C(=O)O.O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3.c1ccncc1>>CCCCCCCCCCCCCCCCOP(=O)(O)OC[C@H](N)C(=O)O,,c1ccncc1,,,,test
US20120264735A1,Cn1cc(-n2ccc(=O)c(Cc3cccc(-c4ncc(NC(=O)OC(C)(C)C)cn4)c3)n2)cn1>>Cn1cc(-n2ccc(=O)c(Cc3cccc(-c4ncc(N)cn4)c3)n2)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04073921,CCCCC(C#N)(CO)c1ccc(Cl)cc1Cl.CS(=O)(=O)Cl>>CCCCC(C#N)(COS(C)(=O)=O)c1ccc(Cl)cc1Cl,,CCN(CC)CC,,c1ccccc1,,test
US04868061,C=CCOC(=O)NCC(=O)O.CO>>C=CCOC(=O)NCC(=O)OC,,CO,,Cl,O=C([O-])O.[Na+],test
US05607943,CCOC(=O)CC(=O)OC(C)(C)C.COc1ccc(CCN)cc1OC>>CCOC(=O)CC(=O)OC(C)(C)C.COc1ccc(CC[NH-])cc1OC,,ClCCl,,,,test
US04146646,NC(NC(=O)c1ccccc1)C(Cl)(Cl)Cl.O=C(Cl)CCl>>O=C(CCl)NC(NC(=O)c1ccccc1)C(Cl)(Cl)Cl,,CC(C)=O,,CCN(CC)CC,O,test
US20060105458A1,CCc1cc(=O)oc2cc(OC)ccc12.O=[Se]=O>>COc1ccc2c(C(C)O)cc(=O)oc2c1,,COCCOCCOC,,,,test
US04367234,CCOC(=N)C(O)c1ccccc1OC.O=C(Cl)Cl>>COc1ccccc1C1OC(=O)NC1=O,,C1CCOC1,,CCN(CC)CC,Cl,test
US20090082358A1,O=C(c1ccc(C(F)(F)F)cc1)c1cnccc1CCN1C(=O)c2ccccc2C1=O>>FC(F)(F)c1ccc(C2=NCCc3ccncc32)cc1,,CCO,,NN,O,test
US20030119670A1,CS(=O)(=O)Cl.Cc1ccc(-c2ccccc2)cc1CO>>Cc1ccc(-c2ccccc2)cc1COS(C)(=O)=O,,CCOC(C)=O,,CCN(CC)CC,Cl,test
US04940710,FCC1CNCCN1.O=C(O)c1cn(C2CC2)c2cc(F)c(F)cc2c1=O>>O=C(O)c1cn(C2CC2)c2cc(N3CCNC(CF)C3)c(F)cc2c1=O,,c1ccncc1,,,,test
US20140148474A1,CCOC(=O)C1CCC(Cc2ncc(-c3cc(C)cc(Nc4nccc(C)n4)c3)s2)CC1>>Cc1cc(Nc2nccc(C)n2)cc(-c2cnc(CC3CCC(C(=O)O)CC3)s2)c1,,CO,,Cl,[Na+].[OH-],test
US20130190293A1,Brc1ccc2ccccc2c1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>Cc1ccc2c(c1)c1c(n2-c2ccc3ccccc3c2)CCN(C)C1,[Cu]I,CN(C)C=O,O,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US04032527,CCN(CC)c1cccc(C)c1.O=C1OC(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c21>>CCN(CC)c1ccc(C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2C(=O)O)c(C)c1,,Clc1ccccc1Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US04046898,Br.O=[N+]([O-])c1ccc(Cl)c(C2CC3=NCCN3C2)c1Cl>>Br.Nc1ccc(Cl)c(C2CC3=NCCN3C2)c1Cl,[Ni],O,,[H][H],,test
US20140349991A1,CCOC(=O)Cl.Cc1c(C2CCNCC2)oc2c(C)c(O)ccc2c1=O>>CCOC(=O)N1CCC(c2oc3c(C)c(O)ccc3c(=O)c2C)CC1,,CN(C)C=O,,c1ccncc1,,test
US05051413,CCC/C(=C\C(NC=O)C(=O)OCC)CP(=O)(OC)OC>>CCC/C(=C\C(N)C(=O)O)CP(=O)(O)O,,O,,,,test
US20130324576A1,CCOC(c1ccc(Cl)cc1)C1CCN(C(=O)OC(C)(C)C)CC1.Cl>>CCOC(c1ccc(Cl)cc1)C1CCNCC1.Cl,,CO,,,,test
US05616599,BrCc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1.CCCc1nc(C(C)(C)O)c(C(=O)OCC)[nH]1>>CCCc1nc(C(C)(C)O)c(C(=O)OCC)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20080114005A1,CCCc1nn(C)c2c(=O)[nH]c(C)nc12.CCOC(=O)C(C)(C)Oc1ccc(CCCOS(C)(=O)=O)cc1>>CCCc1nn(C)c2c(=O)n(CCCc3ccc(OC(C)(C)C(=O)OCC)cc3)c(C)nc12,,CCOC(C)=O,CN(C)C=O,,,test
US04544657,COc1ccc(Cc2ncc(CCl)c3cc(OC)c(OC)cc23)cc1OC.COc1ccccc1C1CCNCC1>>COc1ccc(Cc2ncc(CN3CCC(c4ccccc4OC)CC3)c3cc(OC)c(OC)cc23)cc1OC,,CS(C)=O,O,CCN(CC)CC,,test
US20060035908A1,Nc1ncc(CCN2C(=O)c3ccccc3C2=O)s1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ncc(CCN2C(=O)c3ccccc3C2=O)s1)Oc1ccccc1,,CCOC(C)=O,ClCCl,Br,,test
US20090270351A1,CC(C)(C)OC(=O)c1ccc(C[PH](=O)O)cc1.CCOP(C)(=O)c1ccc(C(=O)OC(C)(C)C)cc1>>COP(=O)(c1ccccc1)c1ccc(C(=O)O)cc1,,C1COCCO1,,Cl,[K+].[OH-],test
US20140011845A1,CCOC(=O)Cl.CON1CCC(CC2NC(=O)C(c3cc(C)ccc3C)=C2O)CC1>>CCOC(=O)OC1=C(c2cc(C)ccc2C)C(=O)NC1CC1CCN(OC)CC1,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20110136801A1,CC(C)(C)[Si](C)(C)Cl.Oc1cc(F)cc(Br)c1>>CC(C)(C)[Si](C)(C)Oc1cc(F)cc(Br)c1,,C1CCOC1,,c1c[nH]cn1,,test
US20110086854A1,COC(=O)CN1C[C@H](c2cccc(Cl)c2F)[C@@](C#N)(c2ccc(Cl)cc2F)[C@@H]1CC(C)(C)C>>CC(C)(C)C[C@@H]1N(CC(=O)O)C[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F,,C1CCOC1,CO,[K+].[OH-],,test
US20100305096A1,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C3CN(C(=O)OC(C)(C)C)C3)n(C)c2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C3CNC3)n(C)c2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080090834A1,Cc1ccc(-n2cc(-c3nc(C)cs3)nc2-c2ccc(Nc3ncccc3[N+](=O)[O-])cc2)cn1>>Cc1ccc(-n2cc(-c3nc(C)cs3)nc2-c2ccc(Nc3ncccc3N)cc2)cn1,[Pd],CO,,[H][H],,test
US20150037280A1,Cc1c(C(=O)Nc2ccc(Oc3ccnc(N)c3)c(F)c2)c(=O)n(-c2ccccc2)n1C.O=C(Cl)C1CC1>>Cc1c(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c(=O)n(-c2ccccc2)n1C,,ClCCl,O,CCN(CC)CC,O=C([O-])[O-].[Na+].[Na+],test
US20070184302A1,CC1(C)c2ccccc2-c2ccc(I)cc21.Cc1ccccc1>>C=Cc1ccc2c(c1)C(C)(C)c1ccccc1-2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US06143764,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.O=C=Nc1cccc2ccccc12>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4cccc5ccccc45)cc3)c2cc1OC,,Cc1ccccc1,,,,test
USRE039606E1,CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)C(=O)O.O=C(CNC(=O)OCC1c2ccccc2-c2ccccc21)Oc1c(F)c(F)c(F)c(F)c1F>>CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)O,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20150158843A1,CCOC(=O)[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1N.O=C(Cl)CCCCBr>>CCOC(=O)[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1NC(=O)CCCCBr,,ClCCl,,CCN(CC)CC,,test
US20080255167A1,CN(C)C=O.ClCCl.O=C(O)CCc1cccc(Br)c1>>CCOC(=O)CCc1cccc(Br)c1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20150057238A1,COS(=O)(=O)OC.O=C(O)C=CC(=O)c1ccc(Cl)c(Cl)c1>>COC(=O)C=CC(=O)c1ccc(Cl)c(Cl)c1,,CC(C)=O,,O=C([O-])O.[Na+],,test
US20140329867A1,O=[N+]([O-])c1ccc(Cl)nc1.Oc1ccc(C2CCCCC2)cc1>>O=[N+]([O-])c1ccc(Oc2ccc(C3CCCCC3)cc2)nc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05563280,COc1ccc2oc(=O)cc(Cl)c2c1.Oc1c(Cl)cccc1Cl>>COc1ccc2oc(=O)cc(Oc3c(Cl)cccc3Cl)c2c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100216810A1,N#Cc1c(Oc2ccc(F)c(NC(=O)C(F)(F)F)c2)ccc2nc(N)sc12.O=C(Cl)C1CC1>>N#Cc1c(Oc2ccc(F)c(NC(=O)C(F)(F)F)c2)ccc2nc(NC(=O)C3CC3)sc12,,C1CCOC1,CCOC(C)=O,c1ccncc1,,test
US20060040999A1,CC(C)(C)[Si](C)(C)OCc1cscn1.II>>CC(C)(C)[Si](C)(C)OCc1csc(I)n1,,C1CCOC1,,[Li]CCCC,,test
US04450169,CC1(C)[C@@H](C=C2CCSC2=O)[C@H]1C(=O)Cl.OCc1cnc(Oc2ccccc2)s1>>CC1(C)[C@@H](C=C2CCSC2=O)[C@H]1C(=O)OCc1cnc(Oc2ccccc2)s1,,c1ccccc1,,Cl,c1ccncc1,test
US20150148313A1,Cc1cc(C(Nc2cc3ccnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c3cc2F)C(=O)N(C)Cc2cc(N)ccc2S(=O)(=O)C2CC2)ccc1[C@@H](C)CO.O=C(Cl)Cl>>Cc1cc2ccc1[C@@H](C)COC(=O)Nc1ccc(S(=O)(=O)C3CC3)c(c1)CN(C)C(=O)[C@@H]2Nc1cc2ccnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c2cc1F,,CC#N,ClCCl,,,test
US20130310362A1,CC(C)(C)OC(=O)N1CC(C(=O)O)C1.Cc1cccc(C(N)=NN)n1>>Cc1cccc(C(N)=NNC(=O)C2CN(C(=O)OC(C)(C)C)C2)n1,,ClCCl,,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US04704156,BrCc1ccccc1.O=C(O)C1(Cl)CC1(Cl)Cl>>O=C(OCc1ccccc1)C1(Cl)CC1(Cl)Cl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06008230,Cc1ccnc2c([N+](=O)[O-])cccc12>>Cc1ccnc2c(N)cccc12,,CO,,NN,O,test
US20120122842A1,COC(=O)c1cnc(N)s1.O=Cc1ccc(-c2cccnc2)cc1>>COC(=O)c1cnc(NCc2ccc(-c3cccnc3)cc2)s1,,Cc1ccccc1,,CC(=O)O,[BH4-].[Na+],test
US20090163552A1,N#Cc1ccc(N)cc1.O=C(O)C(C1CCCCC1)n1c(-c2ccc(Cl)cc2)nc2cc(F)c(F)cc21>>N#Cc1ccc(NC(=O)C(C2CCCCC2)n2c(-c3ccc(Cl)cc3)nc3cc(F)c(F)cc32)cc1,,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20100215772A1,FC1(C2CC2)CNC1.O=C(CC(F)(F)F)Nc1ccc(Sc2nc(Cl)cc(Nc3ncns3)n2)cc1>>O=C(CC(F)(F)F)Nc1ccc(Sc2nc(Nc3ncns3)cc(N3CC(F)(C4CC4)C3)n2)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,Cl,test
US20120196813A1,CCOc1ccc(Cc2cc([C@@H]3OC4(CC4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)ccc2Cl)cc1>>CCOc1ccc(Cc2cc([C@@H]3OC4(CC4)[C@@H](O)[C@H](O)[C@H]3O)ccc2Cl)cc1,[Pd],CO,,Cl,,test
US04956465,CCOC(=O)CC#N.CCOC(=O)c1cn(C2CC2)c2cc(F)c(F)cc2c1=O>>CCOC(=O)c1cn(C2CC2)c2cc(C(C#N)C(=O)OCC)c(F)cc2c1=O,,C1COCCO1,O,Cl,[H-].[Na+],test
US20090221837A1,CC(C)(C#N)c1cc(CBr)cc(C(C)(C)C#N)c1.Nn1cnnc1>>CC(C)(C#N)c1cc(C[NH+]2CN(N)C=N2)cc(C(C)(C)C#N)c1.[Br-],,CC(C)O,,,,test
US20060235033A1,COc1cc2nccc(Oc3ccc(N)cc3OC)c2cc1OC.C[C@H](N)c1ccc(F)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)N[C@@H](C)c4ccc(F)cc4)cc3OC)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20110201604A1,C[C@@H](O)CN1CC[C@@H](N)C1.Cn1c(Nc2nc3ccc(Cl)cc3s2)nc2cc(C(=O)O)ccc21>>C[C@@H](O)CN1CC[C@@H](NC(=O)c2ccc3c(c2)nc(Nc2nc4ccc(Cl)cc4s2)n3C)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100004239A1,CC(=O)C(=NO)C(=O)OC(C)(C)C.CCOC(=O)CC(=O)CC(=O)OCC>>CCOC(=O)Cc1[nH]c(C(=O)OC(C)(C)C)c(C)c1C(=O)OCC,[Zn],CC(=O)O,,O,,test
US20150361059A1,COc1ccc2cc(Br)ccc2c1CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)COc2ccccc21.Cl>>COc1ccc2cc(Br)ccc2c1CN1C(=O)[C@@H](N)COc2ccccc21.Cl,,C1COCCO1,,,,test
US20060122400A1,C[N+](=O)[O-].O=Cc1ccco1>>O=[N+]([O-])C=Cc1ccco1,,CO,O,Cl,[Na+].[OH-],test
US20090036443A1,COC(=O)c1cc(-c2ccccc2)n(Cc2ccccc2)c1Cl>>OCc1cc(-c2ccccc2)n(Cc2ccccc2)c1Cl,,ClCCl,,CC(C)C[Al+]CC(C)C.[H-],,test
US04369312,CC(C)(C)OC(=O)NN.CC1=C(C(=O)OCC(Cl)(Cl)Cl)N2C(=O)C(=O)[C@H]2SC1>>CC1=C(C(=O)OCC(Cl)(Cl)Cl)N2C(=O)/C(=N\NC(=O)OC(C)(C)C)[C@H]2SC1,,ClC(Cl)Cl,,Cl,c1ccncc1,test
US20130090298A1,CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)O.OC[C@H]1O[C@@H](c2ccc(Cl)c(Cc3ncc(-c4ccco4)s3)c2)[C@H](O)[C@@H](O)[C@@H]1O>>CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)OC[C@H]1O[C@@H](c2ccc(Cl)c(Cc3ncc(-c4ccco4)s3)c2)[C@H](O)[C@@H](O)[C@@H]1O,CN(C)c1ccncc1,CN(C)C=O,,CCN=C=NCCCN(C)C,Cl,test
US20060183921A1,CCOC(=O)c1c(-c2ccc(Cl)cc2)csc1N.O=C1OC(=O)c2ccccc21>>CCOC(=O)c1c(-c2ccc(Cl)cc2)csc1N1C(=O)c2ccccc2C1=O,,CC(=O)O,,,,test
US20070082880A1,N#Cc1cnc2sc(I)cc2c1Cl.Nc1ccc2[nH]ccc2c1>>Cl.N#Cc1cnc2sc(I)cc2c1Nc1ccc2[nH]ccc2c1,,CCO,,,,test
US20140178374A1,O=Cc1cn(Cc2ccc(Cl)cc2)c2ccccc12.O=[N+]([O-])c1ccc2c(c1)Cc1ccccc1-2>>O=[N+]([O-])c1ccc2c(c1)C(=Cc1cn(Cc3ccc(Cl)cc3)c3ccccc13)c1ccccc1-2,,CO,,,,test
US20140315888A1,COC(OC)OC.NNc1nc2cc(I)cnc2nc1N1CCN2CCCC2C1>>Ic1cnc2nc(N3CCN4CCCC4C3)c3nncn3c2c1,,CCOCC,,,,test
US20040023947A1,CCOC(=O)C1=CNC(C(=O)OCC)Cc2c1[nH]c1ccccc21>>CCOC(=O)C1=CNC(C(=O)O)Cc2c1[nH]c1ccccc21,,CO,,[Li+].[OH-],,test
US20140038919A1,CC(C)(C)OC(=O)NN.CS(=O)(=O)N(CCCC(=O)Cl)c1cc2oc(-c3ccc(F)cc3)c(-c3ncc[nH]3)c2cc1C1CC1>>CC(C)(C)OC(=O)NNC(=O)CCCN(c1cc2oc(-c3ccc(F)cc3)c(-c3ncc[nH]3)c2cc1C1CC1)S(C)(=O)=O,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,ClCCl,test
US20110118245A1,CC(C)(C)c1cc(NC(=O)Oc2ccccc2)n(-c2ccccc2)n1.COCCOc1cc2ncnc(Oc3cccc(N)c3)c2cc1OC>>COCCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C)nn4-c4ccccc4)c3)c2cc1OC,CN(C)c1ccncc1,,,CCN(C(C)C)C(C)C,,test
US20050176956A1,CC(=O)N(C(C)=O)c1nc2nc[nH]c2c(=O)[nH]1.CC(=O)OCOC(COC(C)=O)COC(C)=O>>CC(=O)Nc1nc2ncn(COC(COC(C)=O)COC(C)=O)c2c(=O)[nH]1,,CN(C)C=O,CO,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20140206618A1,CC(C)(C)OC(=O)N1CCN[C@@H](CO)C1.Cc1c(C#N)cccc1C(=O)CCl>>Cc1c(C#N)cccc1C(=O)CN1CCN(C(=O)OC(C)(C)C)C[C@@H]1CO,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20110105461A1,BrCC1CO1.CC(=O)c1cc(Br)cc(F)c1O>>CC(=O)c1cc(Br)cc(F)c1OCC1CO1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20050197361A1,C1CCNCC1.CSc1nc2c(cc1C#N)C(=O)CC(C)(C)C2>>CC1(C)CC(=O)c2cc(C#N)c(N3CCCCC3)nc2C1,,CCO,,,,test
US06756380B1,CCN(CC)CC.CCN=C=NCCCN(C)C.CSc1ncc(-c2ccccc2C)c(C(=O)O)n1.ClCCl.On1nnc2ccccc21>>CSc1ncc(-c2ccccc2C)c(C(=O)N(C)Cc2cc(C)cc(C)c2)n1,,ClCCl,,Cl,,test
US20110269700A1,CCN=C=O.CCOc1ccc(Cc2cc([C@@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3O)ccc2Cl)cc1>>CCNC(=O)NC[C@H]1O[C@@H](c2ccc(Cl)c(Cc3ccc(OCC)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O,,ClC(Cl)Cl,O,,,test
US20150191474A1,CCS.O=Cc1ccc(Cl)cc1F>>CCSc1cc(Cl)ccc1C=O,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080188506A1,O=C1CC(c2ccc(Cl)cc2)C2(C(=O)Nc3cc(Cl)ccc32)C(c2cccc(F)c2)N1>>O=C1Nc2cc(Cl)ccc2C12C(c1ccc(Cl)cc1)CCNC2c1cccc(F)c1,,CO,,[BH4-].[Na+],,test
US20150018335A1,Clc1cccc(N2CCOCC2)c1CN1CCNCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OC(C(F)(F)F)C(F)(F)F>>O=C(OC(C(F)(F)F)C(F)(F)F)N1CCN(Cc2c(Cl)cccc2N2CCOCC2)CC1,,ClCCl,O,CCN(C(C)C)C(C)C,,test
US20140296208A1,C#Cc1cc(Nc2cc(Oc3ccc(NC(=O)OC(C)(C)C)c4ccccc34)ccn2)cc(C(=O)O)c1.COCCOCCOC[C@H](C)N>>C#Cc1cc(Nc2cc(Oc3ccc(NC(=O)OC(C)(C)C)c4ccccc34)ccn2)cc(C(=O)N[C@@H](C)COCCOCCOC)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05506227,CC(=O)OCc1ccccn1.CS(=O)(=O)Cl>>CS(=O)(=O)OCc1ccccn1,,CCN(CC)CC,,,,test
US20020156064A1,Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)C>>Cc1c(N)cccc1S(=O)(=O)N(C)C,[Pd],,,CCO,,test
US20120040954A1,CN(C)C=O.Cc1cc(Br)ccn1>>Cc1cc(C=O)ccn1,,C1CCOC1,,[Li]CCCC,,test
US20130053366A1,CCOC(=O)CBr.Cc1ccc2c(c1)c1c(n2CC(O)c2ccncc2)CCNC1>>CCOC(=O)CN1CCc2c(c3cc(C)ccc3n2CC(O)c2ccncc2)C1,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20050222261A1,CCN(Cc1ccc(C(C)(C)C)cc1)C(=O)COc1ccc(CCOc2ccccc2C(=O)OC)cc1>>CCN(Cc1ccc(C(C)(C)C)cc1)C(=O)COc1ccc(CCOc2ccccc2C(=O)O)cc1,,C1CCOC1,,O,,test
US20090137530A1,CCCCCCCOc1ccc(CCC2(NC(=O)OC(C)(C)C)COC(C)(C)OC2)cc1C#N.Cl>>CCCCCCCOc1ccc(CCC(N)(CO)CO)cc1C#N.Cl,,C1COCCO1,CCO,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20020040016A1,O=C(CCCCl)Oc1cccc(F)c1>>CC1CC(=O)c2c(O)cc(F)cc21,,CCOC(C)=O,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20020160996A1,CC(Cl)OC(=O)Cl.Cc1cc(C)c2c(c1C)OC1(CCN(Cc3ccccc3)CC1)C2c1ccc(C(C)C)cc1>>Cc1cc(C)c2c(c1C)OC1(CCNCC1)C2c1ccc(C(C)C)cc1.Cl,,C1CCOC1,,,,test
US20080032973A1,N#Cc1cc(Br)ccc1F.Nc1ccccc1Cl>>N#Cc1cc(Br)ccc1Nc1ccccc1Cl,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20060142211A1,COc1cc2oc(-c3ccc([N+](=O)[O-])cc3)cc(=O)c2c(OC)c1OC>>COc1cc(O)c(C(C)=O)c(OC)c1OC,,ClCCl,,BrB(Br)Br,,test
US20110092479A1,CCCS(=O)(=O)Nc1ccc(F)c(C(=O)O)c1Cl.COc1n[nH]c2ncc(N)cc12>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]nc(OC)c3c2)c1Cl,,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20030187014A1,C/C=C(\N)C#N.Cc1cccc(NN)n1>>Cc1cccc(-n2nc(C)cc2N)n1,,CCO,,CC(=O)O,,test
US20100056565A1,ClC1CN2CCC1CC2.SCc1ccccc1>>c1ccc(CSC2CN3CCC2CC3)cc1,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20120202691A1,COC1=CC(=O)C(=CC2CCOCC2)C1>>COC1=CC(=O)C(CC2CCOCC2)C1,[Pd],CCO,,[H][H],,test
US04420631,CC(C)=CCc1ccc(C(C)C(=O)O)cc1.CCOS(=O)(=O)OCC>>CCOC(=O)C(C)c1ccc(CC=C(C)C)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090153041A1,Nc1ccccc1O.O=C(Cl)c1ccc(Br)cc1>>O=C(Nc1ccccc1O)c1ccc(Br)cc1,,O,,C1CCOC1,CCN(CC)CC,test
US20060074075A1,CCOC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1C.COC(OC)N(C)C>>CCOC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1C=CN(C)C,,CN(C)C=O,,,,test
US20060194783A1,CC(C)(C)OC(=O)N1CC(Br)C(=O)N(CC2CC2)CC1c1ccccc1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1C[C@@H](N=[N+]=[N-])C(=O)N(CC2CC2)C[C@@H]1c1ccccc1,,CN(C)C=O,,O,,test
US05030641,CC(C)(N=[N+]=[N-])C(=O)N1CCC(O)CC1.O=C([O-])C(=O)[O-]>>CC(C)(N)C(=O)N1CCC(O)CC1.O=C(O)C(=O)O,[Ni],CO,,[H][H],,test
US20150197509A1,CC1(C)OB(c2ccc(C(F)(F)F)cc2)OC1(C)C.N#Cc1cncc(Br)c1>>N#Cc1cncc(-c2ccc(C(F)(F)F)cc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160221972A1,COC(=O)CN(Cc1ccc(C(=O)OC)cc1N)C(=O)OC(C)(C)C>>COC(=O)c1ccc2c(c1)NC(=O)CN(C(=O)OC(C)(C)C)C2,,Cc1ccccc1,,,,test
US05463011,CCN(CC)CC.COC(=O)COc1ccc(C(=O)NC(=O)Nc2ccc(C(=N)SC)cc2)cc1>>N=C(N)c1ccc(NC(=O)NC(=O)c2ccc(OCC(=O)O)cc2)cc1,,CO,O,I,,test
US20130217668A1,CC(C)CBr.O=C(/N=c1\[nH]c2cnc(OCCN3CCCCC3)cc2n1C1CCNCC1)c1ccccc1>>CC(C)CN1CCC(n2/c(=N/C(=O)c3ccccc3)[nH]c3cnc(OCCN4CCCCC4)cc32)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050277630A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCSCC3=O)C(=O)O1.COC(OC)N(C)C>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCSC(=CN(C)C)C3=O)C(=O)O1,,CCCO,,,,test
US20160083354A1,COC(=O)c1ccc(CBr)cc1.Nc1cccc(F)c1F>>COC(=O)c1ccc(CNc2cccc(F)c2F)cc1,,CC#N,,CCN(C(C)C)C(C)C,O,test
US20100063091A1,COCCCc1cc(CCCOC)cc(C(=O)NC2CC2)c1>>COCCCc1cc(CCCOC)cc(CNC2CC2)c1,,C1CCOC1,,B,CSC,test
US04806549,COc1cccc2c(=O)c(C(=O)C(C)C)c[nH]c12.O=P(Cl)(Cl)Cl>>COc1cccc2c(Cl)c(C(=O)C(C)C)cnc12,,ClC(Cl)Cl,,,,test
US20100113462A1,CCOC(=O)C1(N)Cc2ccccc2C1.O=C(O)C1CC2CCC1C2>>CCOC(=O)C1(NC(=O)C2CC3CCC2C3)Cc2ccccc2C1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160024078A1,c1ccc(-n2nnc3ccccc32)nc1>>c1ccc2c(c1)[nH]c1ncccc12,,O,,[Na+].[OH-],,test
US20040054172A1,C=COCCONC(=O)c1cc(F)c(F)c(F)c1Nc1ccc(I)cc1C>>Cc1cc(I)ccc1Nc1c(C(=O)NOCCO)cc(F)c(F)c1F,,CCO,,Cl,O,test
US20060025414A1,COC(=O)c1ccc(CN(C)C)cc1.NN>>CN(C)Cc1ccc(C(=O)NN)cc1,,CO,,O,,test
US20060084643A1,N#Cc1c(N)sc2ccccc12.O=[N+]([O-])c1cc(F)ccc1F>>N#Cc1c(Nc2ccc(F)cc2[N+](=O)[O-])sc2ccccc12,,CS(C)=O,,[Li+].[OH-],,test
US20140256710A1,CI.COc1nccc2c(I)c[nH]c12>>COc1nccc2c(I)cn(C)c12,,CN(C)C=O,,[H-].[Na+],,test
US05872138,BrCC1CCCCC1.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OCC2CCCCC2)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140275011A1,N#Cc1c[nH]c2cc(Br)ccc12.OCc1ccccc1>>N#Cc1cn(Cc2ccccc2)c2cc(Br)ccc12,,Cc1ccccc1,,CCCCP(=CC#N)(CCCC)CCCC,,test
US05135955,BrCC1CCCCC1.COc1ccc(C=O)cc1O>>COc1ccc(C=O)cc1OCC1CCCCC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20140011799A1,COC(=O)C[C@@](C)(O)C(=O)OC.O=C=NC(=O)C(Cl)(Cl)Cl>>C[C@]1(CC(=O)O)OC(=O)NC1=O,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20130064770A1,COc1ccccc1N1CCNCC1.O=c1cnn(CCCCCl)c(=O)n1CCF>>COc1ccccc1N1CCN(CCCCn2ncc(=O)n(CCF)c2=O)CC1,,CCCCO,,CCN(CC)CC,,test
US05254718,CC(O)C(=O)O.OCCCl>>CC(O)C(=O)OCCCl,,Cc1ccccc1,,O,O=S(=O)(O)O,test
US05455258,COC(=O)C1(N(Cc2ccccc2)S(=O)(=O)c2ccc(OC)cc2)CCSCC1>>COc1ccc(S(=O)(=O)N(Cc2ccccc2)C2(C(=O)O)CCSCC2)cc1,,CO,,[Na+].[OH-],,test
US20140051679A1,Fc1ccc(I)cc1.OC1CCN(CCF)CC1>>FCCN1CCC(Oc2ccc(I)cc2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20130281434A1,Cc1cc2nc(-c3ccnc(Cl)c3)sc2c(-c2ccc(Cl)cc2)c1[C@@H](COC(=O)C(C)(C)C)OC(C)(C)C.Cc1cc2nc(Br)sc2c(-c2ccc(Cl)cc2)c1[C@@H](COC(=O)C(C)(C)C)OC(C)(C)C.OB(O)c1ccnc(Cl)c1>>Cc1cc2nc(-c3ccnc(-c4ccc5cnn(C)c5c4)c3)sc2c(-c2ccc(Cl)cc2)c1[C@@H](CO)OC(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20090253687A1,O=C(Cl)C(=O)Cl.O=C(O)Cc1cccc(Cl)c1>>O=C(Cl)Cc1cccc(Cl)c1,CN(C)C=O,C1CCOC1,,,,test
US20150152113A1,NNc1nncc(N2CCC(c3ncccc3C(F)(F)F)CC2)c1Cl.O=C(Cl)CC1CC1>>O=C(CC1CC1)NNc1nncc(N2CCC(c3ncccc3C(F)(F)F)CC2)c1Cl,,CCOC(C)=O,O,C1CCOC1,O=C([O-])O.[Na+],test
US20090054405A1,CC(=O)OC(C)=O.Nc1nc2cccc(Br)c2s1>>CC(=O)Nc1nc2cccc(Br)c2s1,CN(C)c1ccncc1,ClCCl,,,,test
US20040157836A1,CCc1ccc(NS(=O)(=O)c2ccc(F)cc2CCCCO)c(C(=O)OC)c1OC.CS(=O)(=O)Cl>>CCc1ccc(NS(=O)(=O)c2ccc(F)cc2CCCCOS(C)(=O)=O)c(C(=O)OC)c1OC,,ClCCl,,c1ccncc1,,test
US05248447,CCCCBr.CCCCC[C@@H]1CC[C@@H](COc2ccc(O)c(F)c2F)CC1>>CCCCC[C@@H]1CC[C@@H](COc2ccc(OCCCC)c(F)c2F)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060121545A1,CCCCNCC(=O)C(CCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)C(=O)O>>NCC(=O)C(CCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US04535183,CCCOc1ccc(OC(C)=O)cc1OC>>CCCOc1ccc(O)cc1OC,,CO,,[Na+].[OH-],,test
US20140371203A1,Brc1csc2ncnc(N3C4CCC3CC(NC3CCC3)C4)c12.C=O>>CN(C1CCC1)C1CC2CCC(C1)N2c1ncnc2scc(Br)c12,,O=CO,,,,test
US20140179667A1,CC(C)I.CCOC(C)=O.CN(C)C=O.Cc1c(O)cccc1C(=O)O>>Cc1c(OC(C)C)cccc1C(=O)OC(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090118263A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCCNC.COC(=O)Cc1cccc(OCCBr)c1>>COC(=O)Cc1cccc(OCCN(C)CCN(C)C(=O)OC(C)(C)C)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130079313A1,COc1ccc(NC(=O)CC(=O)O)cc1OC.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>COc1ccc(NC(=O)CC(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1OC,CN(C)c1ccncc1,CN(C)C=O,O,ClCCCl,,test
US20160221972A1,COC(=O)c1ccc2c(c1)OCCNC2.O=C1CCCCC1>>COC(=O)c1ccc2c(c1)OCCN(C1CCCCC1)C2,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20110077252A1,COC(=O)C#CC(=O)OC.N=C(NO)c1ccc(N)cn1>>COC(=O)c1nc(-c2ccc(N)cn2)nc(O)c1O,,[Na+],[OH-],CO,,test
US20070135477A1,COc1ccc(C(C)(C)C)cc1C(=O)Nc1c[nH]nc1C(=O)O.Nc1ccccc1N>>COc1ccc(C(C)(C)C)cc1C(=O)Nc1c[nH]nc1C(=O)Nc1ccccc1N,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US06001997,CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)OCc3ccc(OC)cc3)=C([C@@H]3CCCO3)CS[C@H]12)c1csc(N)n1.O=C(OO)c1cccc(Cl)c1>>CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)OCc3ccc(OC)cc3)=C([C@@H]3CCCO3)C[S@](=O)[C@H]12)c1csc(N)n1,,CCOC(C)=O,,,,test
US20160060255A1,COC(=O)C1CCC(O)(c2ncc(-c3cc(Nc4nccc(OC(C)C)n4)cc(C)n3)s2)CC1(C)C>>Cc1cc(Nc2nccc(OC(C)C)n2)cc(-c2cnc(C3(O)CCC(C(=O)O)C(C)(C)C3)s2)n1,,CCOC(C)=O,,CCO,[K+].[OH-],test
US05376684,CC(NC[C@H](O)CP(=O)(O)CC1CC=CCC1)c1ccc(Cl)c(Cl)c1>>CC(NC[C@H](O)CP(=O)(O)CC1CCCCC1)c1ccc(Cl)c(Cl)c1,[Pd],CCO,,,,test
US05017573,CC(=O)NC1CN(C)CCN(Cc2ccccc2)C1.CC(=O)O>>CC(=O)NC1CNCCN(C)C1.CC(=O)[O-],[Pd],CC(=O)O,,CCO,,test
US20140018309A1,CCN(C(=O)OC(C)(C)C)C1=N[C@H]2[C@H](O[C@H](CO)[C@@H](OCc3ccc(OC)cc3)[C@@H]2OCc2ccc(OC)cc2)S1.CS(=O)(=O)Cl>>CCN(C(=O)OC(C)(C)C)C1=N[C@H]2[C@H](O[C@H](COS(C)(=O)=O)[C@@H](OCc3ccc(OC)cc3)[C@@H]2OCc2ccc(OC)cc2)S1,,ClCCl,c1ccncc1,,,test
US05411980,CCC(=O)Br.CCCCc1nn(-c2cc(N)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Oc2ccccc2)cc1>>CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Oc2ccccc2)cc1,CN(C)c1ccncc1,Cc1ccccc1,,,,test
US20150038437A1,CI.Cc1c(-c2ccc3c(c2)cc2n3CC(NC(=O)OC(C)(C)C)C2)nc(OCc2ccccc2)c(C(=O)OCc2ccccc2)c1OCc1ccccc1>>Cc1c(-c2ccc3c(c2)cc2n3CC(N(C)C(=O)OC(C)(C)C)C2)nc(OCc2ccccc2)c(C(=O)OCc2ccccc2)c1OCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20160222033A1,CCN(Cc1cc(=O)n2c(CO)c(C)sc2n1)c1ccc(F)cc1.CI>>CCN(Cc1cc(=O)n2c(COC)c(C)sc2n1)c1ccc(F)cc1,,C1CCOC1,,[H-].[Na+],,test
US20110306609A1,COCCN1CCN(Cc2cnc3sc(-c4ccccc4N)nc3c2)CC1.O=C(O)c1csc(-c2ccccc2)n1>>COCCN1CCN(Cc2cnc3sc(-c4ccccc4NC(=O)c4csc(-c5ccccc5)n4)nc3c2)CC1,,O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050209278A1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.Oc1ccc(SC(F)(F)F)cc1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(SC(F)(F)F)cc2)CC1,,COCCOCCOC,,Cl,[Na+].[OH-],test
US20020169316A1,BrCCOC1CCCCO1.O=C1C(=NO)Oc2ccccc21>>O=C1C(=NOCCOC2CCCCO2)Oc2ccccc21,,CO,,O,C[O-].[Na+],test
US04975437,CC(=O)CC(=O)OCCC#N.N>>CC(N)=CC(=O)OCCC#N,,CO,,,,test
US20080096877A1,CN(c1cccc2cc(-c3ncc(CCl)s3)[nH]c12)S(=O)(=O)c1cccs1.O=C1NCC2(CCNCC2)O1>>CN(c1cccc2cc(-c3ncc(CN4CCC5(CC4)CNC(=O)O5)s3)[nH]c12)S(=O)(=O)c1cccs1,,O,,CCN(CC)CC,CN(C)C=O,test
US20160039846A1,CN(C)S(C)(=O)=Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.C[Si](C)(C)CCOCn1c(O[C@@H]2CO[C@@H]3[C@H](O)CO[C@H]23)nc2cc(Cl)c(I)nc21>>CN(C)S(C)(=O)=Nc1ccc(-c2nc3c(cc2Cl)nc(O[C@@H]2CO[C@@H]4[C@H](O)CO[C@H]24)n3COCC[Si](C)(C)C)cc1,,C1COCCO1,,,,test
US20140171405A1,COc1cc(OC)c(Cl)c(-c2cc3[nH]ncc3cn2)c1Cl.O=C1CCC(=O)N1I>>COc1cc(OC)c(Cl)c(-c2cc3[nH]nc(I)c3cn2)c1Cl,,ClCCl,,,,test
US20110190300A1,CC(C)(C)OC(=O)N1CCC(=NOC(=O)Nc2ccc(F)cc2)CC1>>O=C(Nc1ccc(F)cc1)ON=C1CCNCC1,,C1COCCO1,,Cl,,test
US20140094462A1,C=CCCC(=O)N[C@@H](COC(=O)N(CC=C)CC(=O)OC(C)(C)C)c1ccccc1>>CC(C)(C)OC(=O)CN1CC=CCCC(=O)N[C@H](c2ccccc2)COC1=O,,Cc1ccccc1,,,,test
US20120316195A1,C=CCC(O)c1ccncc1-c1ccc(C#N)c(OC)c1>>CCCC(O)c1ccncc1-c1ccc(C#N)c(OC)c1,[Pd],CO,,,,test
US20090118335A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=Cc1c[nH]c(-c2ccccc2)n1>>Cc1ccc(S(=O)(=O)n2cc(C=O)nc2-c2ccccc2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20140140928A1,CC(C)(C)OC(=O)N1CCN(c2ccccc2O)CC1.COCCOCCl>>COCCOCOc1ccccc1N1CCN(C(=O)OC(C)(C)C)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20020160986A1,COc1ccc2c(c1)C(C)(C)CC2=O.[N-]=[N+]=[N-]>>COc1ccc2c(c1)C(C)(C)CNC2=O,,O,c1ccccc1,O=S(=O)(O)O,,test
US05093353,CCCc1c(OCCCOc2cccc3c2CCCC3)ccc2c1OC(CCC(=O)OCC)(CCC(=O)OCC)CC2=O>>CCCc1c(OCCCOc2cccc3c2CCCC3)ccc2c1OC(CCCO)(CCCO)CC2O,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05532235,COC(=O)c1ccc(NC(=O)c2ccccc2-c2ccccc2)nc1>>O=C(O)c1ccc(NC(=O)c2ccccc2-c2ccccc2)nc1,,C1CCOC1,,CO,[Na+].[OH-],test
US20040058970A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc2c(c1)C(=O)NC2>>CC(C)(C)OC(=O)Nc1ccc2c(c1)C(=O)NC2,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20150284384A1,CCCCCCC.CCOC(=O)c1nc2cc(C#N)cc(C)n2c1CC1CCC(F)(F)CC1.C[Mg]Br>>Cc1cc(C#N)cc2nc(C(C)(C)O)c(CC3CCC(F)(F)CC3)n12,,CCCCCCC,CCOC(C)=O,C1CCOC1,[Cl-].[NH4+],test
US20070238726A1,COc1ccc(Cn2nc(N3CCCN(C(=O)OC(C)(C)C)CC3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1>>COc1ccc(Cn2nc(N3CCCNCC3)c3c(Oc4ccc(NC(=O)c5ccnn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080119461A1,CC[C@H]1C[C@@]1(NC(=O)OCC[Si](C)(C)C)C(=O)OC(C)(C)C>>CC[C@H]1C[C@@]1(N)C(=O)OC(C)(C)C,,CCOC(C)=O,,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US06265349B1,Cn1c(C(F)(F)F)ccc(-c2c(F)cc(Cl)c3oc(C=O)cc23)c1=O.O=[Cr](=O)=O>>Cn1c(C(F)(F)F)ccc(-c2c(F)cc(Cl)c3oc(C(=O)O)cc23)c1=O,,CC(C)=O,,O,O=S(=O)(O)O,test
US04775497,CC(C)(C)c1cc(Sc2cc(C(C)(C)C)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1.Cl[Si](Cl)(c1ccccc1)c1ccccc1>>CC(C)(C)c1cc2c(c(C(C)(C)C)c1)O[Si](c1ccccc1)(c1ccccc1)Oc1c(cc(C(C)(C)C)cc1C(C)(C)C)S2,,Cc1ccccc1,,CCN(CC)CC,,test
US20110112065A1,COC(CBr)OC.OCc1cc(F)c(Br)cc1O>>Fc1cc2c(cc1Br)OC(CBr)OC2,,C1CCOC1,,O=S(=O)(O)O,,test
US20100004280A1,CN(C)S(=O)(=O)n1cc(CC(C)(C)C)nc1C(C)(O)Cc1ccc(-c2ccc(F)cn2)cc1>>CC(C)(C)Cc1c[nH]c(C(C)(O)Cc2ccc(-c3ccc(F)cn3)cc2)n1,,CO,,Cl,,test
US20120157438A1,CI.O=Cc1ccnc2[nH]ccc12>>Cn1ccc2c(C=O)ccnc21,,CN(C)C=O,O,[H-].[Na+],[Cl-].[NH4+],test
US20050009831A1,COc1ccc(N=C=S)cc1.NC(=O)c1c(Cl)c(-c2ccccc2)n2c1CNCC2>>COc1ccc(NC(=S)N2CCn3c(c(C(N)=O)c(Cl)c3-c3ccccc3)C2)cc1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20120184587A1,COC(=O)c1cc(I)c(O)c(C(C)(C)C)c1.COS(=O)(=O)OC>>COC(=O)c1cc(I)c(OC)c(C(C)(C)C)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110190365A1,CCOC(=O)c1ccc(-n2cc(-c3cc(Cl)cc(Cl)c3)c(C(F)(F)F)n2)cc1C(F)(F)F>>O=C(O)c1ccc(-n2cc(-c3cc(Cl)cc(Cl)c3)c(C(F)(F)F)n2)cc1C(F)(F)F,,CCO,O,[Na+].[OH-],,test
US20050288287A1,C=CS(C)(=O)=O.CC(C)(C)OC(=O)NCCN>>CC(C)(C)OC(=O)N(CCN)CCS(C)(=O)=O,,CO,,CCN(CC)CC,Cl,test
US07618961B2,BrC(Br)(Br)Br.Cc1c(Cl)cccc1S(=O)(=O)Nc1nc(CCO)cs1>>Cc1c(Cl)cccc1S(=O)(=O)Nc1nc(CCBr)cs1,,CN(C)C=O,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130123235A1,COC(=O)c1c(N)ccc2c1ncc1occc12.O=S(=O)(Cl)c1ccc(F)cc1Br>>COC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2Br)ccc2c1ncc1occc12,,c1ccncc1,,,,test
US20120142671A1,CC(C)(C)OC(=O)N[C@H](Cc1cccs1)C(N)=O>>NC(=O)[C@H](N)Cc1cccs1,,ClCCl,O=C(O)C(F)(F)F,,,test
US04898867,CCOC(=O)Cn1c(=O)n(Cc2ccc(Cl)c(Cl)c2)c(=O)c2c(C)csc21.O=C1CCC(=O)N1Br>>CCOC(=O)Cn1c(=O)n(Cc2ccc(Cl)c(Cl)c2)c(=O)c2c(C)c(Br)sc21,,ClC(Cl)(Cl)Cl,,,,test
US20120245137A1,CI.O=C1c2ccccc2C(=O)N1[C@@H]1C[C@@H](CS(=O)(=O)c2cccc(C(F)(F)F)c2)C1>>CC([C@@H]1C[C@@H](N2C(=O)c3ccccc3C2=O)C1)S(=O)(=O)c1cccc(C(F)(F)F)c1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US03939173,NC(=O)c1ccc2c(c1)C(=O)c1ccc(C(N)=O)cc1C2=O>>N#Cc1ccc2c(c1)C(=O)c1ccc(C#N)cc1C2=O,,O,,CN(C)C=O,O=S(Cl)Cl,test
US05362915,COc1ccc(Br)cc1C=O.OO>>COc1ccc(Br)cc1O,,CO,,O=S(=O)(O)O,,test
US04540814,BrBr.COc1ccc(OC)c2ccccc12>>COc1cc(Br)c(OC)c2ccccc12,,CC(=O)O,,,,test
US06329389B1,CN(C)C(=O)C1Cc2ccccc2NC1=O>>CN(C)CC1CNc2ccccc2C1,,O,,Cl,,test
US05716971,CC(C)(C)O/N=C(/c1cc(F)c(Cl)cc1O)c1ncccc1O.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)O/N=C(/c1cc(F)c(Cl)cc1O)c1c(O)ccc[n+]1[O-],,ClC(Cl)Cl,,O=S([O-])O.[Na+],,test
US20100286126A1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.C[C@@H](OCc1ccccc1)C(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O>>C[C@@H](OCc1ccccc1)C(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(N4CC[C@@H](NC(=O)OC(C)(C)C)C4)nc32)[C@H](O)[C@@H]1O,,CC#N,,[I-].[Na+],,test
US20030149016A1,CN(C)C=O.Cc1ncc2sccn12>>Cc1nc(C=O)c2sccn12,,ClCCl,O,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US20160272637A1,CCC(OC)(OC)OC.NNc1ccc([N+](=O)[O-])cn1>>CCc1nnc2ccc([N+](=O)[O-])cn12,,CCO,,,,test
US20020094989A1,CC(=O)O.OCCc1ccncc1>>CC(=O)O.OCCC1CCNCC1,O=[Pt],,,[H][H],,test
US03984397,CC12CC1(C(=O)OCC(Cl)(Cl)Cl)N1C(=O)C(NC(=O)Cc3ccccc3)[C@H]1S2>>CC12CC1(C(=O)O)N1C(=O)C(NC(=O)Cc3ccccc3)[C@H]1S2,[Zn],CC(=O)O,CN(C)C=O,,,test
US20060040918A1,CCOC(=O)CCCBr.Oc1ccc2c(c1)CCN(C1CCC1)CC2>>CCOC(=O)CCCOc1ccc2c(c1)CCN(C1CCC1)CC2,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04803301,C[C@H](O)C(=O)OC(C)(C)C.Oc1ccc(Cl)cc1>>C[C@@H](Oc1ccc(Cl)cc1)C(=O)OC(C)(C)C,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100160308A1,CCOC(=O)c1sc(Nc2cc(C(OC)OC)ccc2[N+](=O)[O-])nc1-c1ccccc1>>CCOC(=O)c1sc(Nc2cc(C=O)ccc2[N+](=O)[O-])nc1-c1ccccc1,,CC#N,,Cl,,test
US20160158207A1,Cn1cc(-c2ccc3c(c2)CCN3C(=O)OC(C)(C)C)c(C#N)n1>>Cn1cc(-c2ccc3c(c2)CCN3)c(C#N)n1,,CCOC(C)=O,,Cl,,test
US20100174065A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Oc1cccc2c1OCCNC2>>CC(C)(C)OC(=O)N1CCOc2c(O)cccc2C1,,ClCCl,,Br,CCN(CC)CC,test
US20150336991A1,O=[N+]([O-])c1ccc(F)c(F)c1.Oc1ccccc1F>>O=[N+]([O-])c1ccc(Oc2ccccc2F)c(F)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05334720,BrCCC=C(c1ccccc1)c1ccccc1.[C-]#N>>N#CCCC=C(c1ccccc1)c1ccccc1,,CN(C)P(=O)(N(C)C)N(C)C,,O,,test
US20110263562A1,C[Mg]Br.O=C(CO[C@@H]1CC[C@@H](c2cc3ccc(OCC4CC4)cc3o2)CC1)N1CCOCC1>>CC(=O)CO[C@@H]1CC[C@@H](c2cc3ccc(OCC4CC4)cc3o2)CC1,,C1CCOC1,,Cc1ccccc1,,test
US04975460,CC(=O)NC1Cc2ccc(O)cc2C1.COC(=O)CBr>>COC(=O)COc1ccc2c(c1)CC(NC(C)=O)C2,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130116235A1,CC1CN(C2COC2)C(C)CN1c1ccc(Nc2cc(-c3ccnc(-n4ncc5c6c(sc5c4=O)CCCC6)c3C=O)cn(C)c2=O)nc1>>C[C@H]1CN(C2COC2)[C@H](C)CN1c1ccc(Nc2cc(-c3ccnc(-n4ncc5c6c(sc5c4=O)CCCC6)c3CO)cn(C)c2=O)nc1,,CO,,[BH4-].[Na+],,test
US20110070317A1,CC(C)(C)OC(=O)N[C@@H]1CCCNC1.O=C(Nc1c[nH]c2ncc(Br)c(F)c12)C1CCC1>>CC(C)(C)OC(=O)N[C@@H]1CCCN(c2c(Br)cnc3[nH]cc(NC(=O)C4CCC4)c23)C1,,CCCCO,CCOC(C)=O,CCN(CC)CC,,test
US20050130941A1,COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(CC1CCCCC1)NC(=O)[C@@H](NC(=O)OC)C(C)C)C(C)C>>COC(=O)N[C@H](C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CN(CC1CCCCC1)NC(=O)[C@@H](NC(=O)OC)C(C)C)C(C)C,,CO,,,,test
US20070004786A1,CI.CN1C(=O)C(c2cccc(Br)c2)(c2c[nH]c(C#N)c2)N=C1N>>CN1C(=O)C(c2cccc(Br)c2)(c2cc(C#N)n(C)c2)N=C1N,,CN(C)C=O,ClC(Cl)Cl,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060014945A1,COC(=O)CCc1ccc(CN([C@@H]2CC(C)(C)CCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)cc1>>CC1(C)CCNC(=O)[C@H](N(Cc2ccc(CCC(=O)O)cc2)S(=O)(=O)c2ccc(Cl)cc2)C1,,CO,O,[Na+].[OH-],,test
US20100222324A1,COS(=O)(=O)OC.Cc1cccc(C)c1C(=O)O>>COC(=O)c1c(C)cccc1C,,CCOC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20010051623A1,CC(C)(C)OC(=O)N1CCN(c2ccc(Br)c3c2C[C@H](N)CC3)CC1.O=C(O)c1ccc(N2CCOCC2)cc1>>CC(C)(C)OC(=O)N1CCN(c2ccc(Br)c3c2C[C@H](NC(=O)c2ccc(N4CCOCC4)cc2)CC3)CC1,,ClCCl,O=S(Cl)Cl,CCN(CC)CC,,test
US20130231328A1,CN(C(=O)OC(C)(C)C)C1CCC(Oc2ncnc3sc4c(c23)[C@@H](C[C@@H](O)c2ccn(COCC[Si](C)(C)C)n2)CC4)CC1.Cl>>CNC1CCC(Oc2ncnc3sc4c(c23)[C@@H](C[C@@H](O)c2cc[nH]n2)CC4)CC1.Cl,,ClCCl,,,,test
US20160060273A1,CCn1ccc2c(OCC(F)(F)F)cc(C=O)cc21.O=C1CCC(=O)N1Cl>>CCn1cc(Cl)c2c(OCC(F)(F)F)cc(C=O)cc21,,CC#N,,,,test
US20070003539A1,CN(C)C(=O)Nc1cccc(C#N)c1>>CN(C)C(=O)Nc1cccc(CN)c1,[Pd],CO,,,,test
US20110077252A1,CC(Cl)C(=O)Cl.N#Cc1ccc(N)nc1>>CC(Cl)C(=O)Nc1ccc(C#N)cn1,,ClCCl,,CCN(CC)CC,,test
US20160208027A1,CCCc1ccc(C(=O)OC(C)CC(C)OC(=O)N(CC)CC)cc1>>CCN(CC)C(=O)OC(C)CC(C)O,,Cc1ccccc1,,C[O-].[Na+],,test
US04371537,CCS(=O)(=O)c1ccc(S(=O)(=O)CC)nc1.Oc1ccc(Cl)c(Cl)c1>>CCS(=O)(=O)c1ccc(Oc2ccc(Cl)c(Cl)c2)nc1,,C1CCOC1,CS(C)=O,CC(C)(C)[O-].[K+],,test
US20110218177A1,COc1cc(OCCOP(=O)(OCc2ccccc2)OCc2ccccc2)ccc1OC(C)=O>>COc1cc(OCCOP(=O)(OCc2ccccc2)OCc2ccccc2)ccc1O,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04589910,CN=C=O.Nc1ccc(Oc2ccc3sncc3c2)cc1>>CNC(=O)Nc1ccc(Oc2ccc3sncc3c2)cc1,,CCN(CC)CC,,Cc1ccccc1,,test
US20050215794A1,CCOC(=O)c1ccc(I)cc1.c1ccc2[nH]ccc2c1>>CCOC(=O)c1ccc(-n2ccc3ccccc32)cc1,[Cu]I,Cc1ccccc1,,CN[C@@H]1CCCC[C@H]1NC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20090124610A1,NC1(Cc2ccc(Cl)cc2)CCNCC1.O=C1COc2c(Cl)ccnc2N1>>NC1(Cc2ccc(Cl)cc2)CCN(c2ccnc3c2OCC(=O)N3)CC1,,CCCCO,,CCN(CC)CC,Cl,test
US20090048269A1,Cc1ccc(Oc2ccnc(Nc3cccc(C(=O)O)c3)c2)c(C)n1.NC1CC1>>Cc1ccc(Oc2ccnc(Nc3cccc(C(=O)NC4CC4)c3)c2)c(C)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030045712A1,C#CCBr.N#Cc1cccc(N)c1>>C#CCNc1cccc(C#N)c1,,CCOC(C)=O,Cc1ccccc1,CCN(C(C)C)C(C)C,,test
US05424431,COc1ccccc1N.O=C(N=C=S)c1ccccc1>>COc1ccccc1NC(N)=S,,CC(C)=O,,,,test
US20120184539A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)c1ncc(Br)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)c1ncc(Br)cc1[N+](=O)[O-],CN(C)c1ccncc1,C1CCOC1,,O=C([O-])O.[Na+],,test
US20040132772A1,Clc1ccnc2ccccc12.NC1CC1>>c1ccc2c(NC3CC3)ccnc2c1,,[Na+],[OH-],,,test
US20090005379A1,CC(C)N1CCC(O)CC1.CCOC(=O)c1cc2cc(O)cnc2n1C(=O)OC(C)(C)C>>CCOC(=O)c1cc2cc(OC3CCN(C(C)C)CC3)cnc2n1C(=O)OC(C)(C)C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20060276515A1,CN1CCNCC1.O=C(NCCC(c1ccc(F)cc1)c1ccc(F)cc1)c1ccc(F)nc1>>CN1CCN(c2ccc(C(=O)NCCC(c3ccc(F)cc3)c3ccc(F)cc3)cn2)CC1,,C1CCOC1,,,,test
US20080076924A1,CCCCC1C=NCCN1>>CCCCC1CNCCN1,[Pd],CCO,,,,test
US20030092720A1,CCc1csc(CCc2ccnc(NC(=O)OC(C)(C)C)c2)c1Br>>CCc1csc(CCc2ccnc(N)c2)c1Br,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110110889A1,CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]cc(C(O)c4ccc(Cl)cc4)c3c2)c1F>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]cc(Cc4ccc(Cl)cc4)c3c2)c1F,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20040132720A1,C[C@H]1CN(c2ccc3occ(C(=O)N(C)C)c3c2)C[C@@H](C)N1Cc1ccccc1>>C[C@H]1CN(c2ccc3occ(C(=O)N(C)C)c3c2)C[C@@H](C)N1,[Pd],CCO,,C1=CCCCC1,,test
US20080293776A1,Nc1cc2ccccc2cc1C(=O)O>>Nc1cc2ccccc2cc1CO,,C1CCOC1,,,,test
US03974212,C=O.COc1ccc(C(=O)CC2CCCC2)c(Cl)c1Cl>>C=C(C(=O)c1ccc(OC)c(Cl)c1Cl)C1CCCC1,,C1COCCO1,,O=S(=O)(O)O,,test
US20060183745A1,CC(=O)OC(C)=O.Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)nc4NCC4CN(Cc5ccccc5)CCO4)ncn3)cccc2s1>>CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)nc4NCC4CN(Cc5ccccc5)CCO4)ncn3)cccc2s1,CN(C)c1ccncc1,ClCCl,,,,test
US20130274256A1,CC1(C)CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]2C1>>CC1(C)CC[C@]2(C(=O)O)CC[C@]3(C)C(=CCC4[C@@]5(C)CCC(=O)C(C)(C)C5CC[C@]43C)C2C1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04997840,CC(=O)c1ccc(Cl)cc1N(C)C=O.O=S(=O)(Cl)Cl>>CN(C=O)c1cc(Cl)ccc1C(=O)CCl,,ClCCl,,O,,test
US04215134,CC(C)(C)C(=O)OC(=O)C(C)(C)C.Cc1cc(OCC(O)CNC(C)(C)C)c2[nH]c(=S)[nH]c2c1.Cl>>Cc1cc(OCC(CNC(C)(C)C)OC(=O)C(C)(C)C)c2[nH]c(=S)[nH]c2c1.Cl,,CN(C)C=O,,Cl,C[O-].[Na+],test
US20120252778A1,CCc1nn2c(C)cc(C)nc2c1Cc1ccc([N+]#N)cc1>>CCc1nn2c(C)cc(C)nc2c1Cc1ccc(NN)cc1,,Cl,,Cl[Sn]Cl,,test
US20140088097A1,CC(C)(C)OC(=O)[C@@H](N)Cc1ccccc1.O=C(Cl)CCl>>CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)CCl,,ClCCl,O,CCN(CC)CC,Cl,test
US20060160840A1,CNCCN.N#Cc1ccc(N)cc1>>CN1CCN=C1c1ccc(N)cc1,,CO,,Cl,,test
US20160264554A1,CC(C)(C)OC(=O)N(Cc1ccc([N+](=O)[O-])cc1)[C@H]1CCC[C@@H](Nc2ncc(Cl)c(-c3n[nH]c4ccccc34)n2)C1>>CC(C)(C)OC(=O)N(Cc1ccc(N)cc1)[C@H]1CCC[C@@H](Nc2ncc(Cl)c(-c3n[nH]c4ccccc34)n2)C1,[Fe],CCO,O,[Cl-].[NH4+],,test
US05344845,COc1cc(C=CC(=O)N[C@@H]2CC[C@@H](C)CC2)ccc1O.ClCCCBr>>COc1cc(C=CC(=O)N[C@@H]2CC[C@@H](C)CC2)ccc1OCCCCl,,CC(=O)CC(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20050020619A1,CNC(=O)/C=C/c1cnc(N)c2c(-c3ccccc3)csc12>>CNC(=O)CCc1cnc(N)c2c(-c3ccccc3)csc12,[Pd],CN(C)C=O,CO,,,test
US20140065136A1,CC1(C)COc2c(nc(Cl)nc2N2CCOCC2)O1.COc1ncc(B(O)O)cn1>>COc1ncc(-c2nc3c(c(N4CCOCC4)n2)OCC(C)(C)O3)cn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US06884868B1,CCOC(=O)c1ccc(F)cc1.COCCCCCCOc1ccc(N2CCNCC2)cc1>>CCOC(=O)c1ccc(N2CCN(c3ccc(OCCCCCCOC)cc3)CC2)cc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100267775A1,CC(C)(C)[Si](C)(C)Cl.Cc1c(O)cccc1Br>>Cc1c(Br)cccc1O[Si](C)(C)C(C)(C)C,,CCCCCC,O,CN(C)C=O,c1c[nH]cn1,test
US20100331326A1,Cc1ccncc1N1CCNC1=O.Fc1cc(Br)ccc1Cl>>Cc1ccncc1N1CCN(c2ccc(Cl)c(F)c2)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US06107481,CC=CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)Cc3ccccc3)[C@H]2SC1.CC=CC1=C(C(=O)OC(C)(C)C)N2C(=O)[C@@H](NC(=O)Cc3ccccc3)[C@H]2SC1>>CC=CC1=C(C(=O)OC(C)(C)C)N2C(=O)[C@@H](c3ccccc3)[C@H]2SC1NC(C)=O,,ClCCl,,,,test
US20060293319A1,COc1cccc([Mg]Br)c1.O=C1Nc2cc(Cl)ccc2C1=O>>COc1cccc(C2(O)C(=O)Nc3cc(Cl)ccc32)c1,,C1CCOC1,,,,test
US20160008326A1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4cncn4CCC)cc2)CCCN3CCC)cc1>>CCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc([S@@](=O)Cc4cncn4CCC)cc2)CCCN3CCC)cc1,,CCOC(C)=O,,CS(=O)(=O)O,,test
US20050131039A1,COC(=O)Cl.COC(=O)c1cccc(N)c1NCc1ccc(-c2ccccc2C#N)cc1>>COC(=O)Nc1cccc(C(=O)OC)c1NCc1ccc(-c2ccccc2C#N)cc1,,c1ccncc1,,,,test
US20070149570A1,N#Cc1ccc(B(O)O)cc1.O=Cc1cc(Br)ccc1OC(F)(F)F>>N#Cc1ccc(-c2ccc(OC(F)(F)F)c(C=O)c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20130023545A1,Cc1cc(-c2nc3cnc(Oc4ccccc4F)nc3o2)cc(C)c1O.O=C(OCc1ccccc1)C1CC(O)C1>>Cc1cc(-c2nc3cnc(Oc4ccccc4F)nc3o2)cc(C)c1OC1CC(C(=O)OCc2ccccc2)C1,,C1CCOC1,CCN(CC)CC,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100056511A1,CC(C)(C)C(=O)N1CCN(c2ccc([N+](=O)[O-])nc2)CC1>>CC(C)(C)CN1CCN(c2ccc([N+](=O)[O-])nc2)CC1,,C1CCOC1,,CSC,,test
US20070099990A1,Cc1c2c(c3ccccc3c1O)OCC2c1ccc(C(C)C)cc1.O=S(=O)([O-])C(F)(F)F>>Cc1c2c(c3ccccc3c1OS(=O)(=O)C(F)(F)F)OCC2c1ccc(C(C)C)cc1,CN(C)c1ccncc1,c1ccncc1,,O,,test
US20150238558A1,COC[C@@H](c1ccccc1)N(Cc1ccc(C(=O)OC)cc1)C(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C>>COC[C@@H](c1ccccc1)N(Cc1ccc(C(=O)OC)cc1)C(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)C(C)(C)C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060004017A1,COCC=O.COc1cc2c(Oc3ccc4[nH]c(C)cc4c3)ncnc2cc1OCC1CCNCC1>>COCCN1CCC(COc2cc3ncnc(Oc4ccc5[nH]c(C)cc5c4)c3cc2OC)CC1,,CO,ClCCl,O=C([O-])O.[Na+],,test
US04466980,CC(=O)OC(C)=O.CC(C)(C)[Si](C)(C)OC1C=C(SCCCCCCO)C(=O)C1>>CC(=O)OCCCCCCSC1=CC(O[Si](C)(C)C(C)(C)C)CC1=O,,CO,,c1ccncc1,,test
US20090137609A1,CCC(CC)(c1ccc(C#CC2(O[Si](C)(C)C)CCSCC2)c(C)c1)c1ccc(-c2cncc(CC(=O)OC)c2)c(C)c1>>CCC(CC)(c1ccc(C#CC2(O)CCSCC2)c(C)c1)c1ccc(-c2cncc(CC(=O)OC)c2)c(C)c1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20050282858A1,C=CC(C)(C)C1(O)CCN(C(=O)OCc2ccccc2)C1>>CCC(C)(C)C1(O)CCNC1,[Pd],CO,,,,test
US20110046151A1,CCN(CC)C(=O)C(O)c1ccccc1.CS(=O)(=O)Cl>>CCN(CC)C(=O)[C@@H](OS(C)(=O)=O)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20070293490A1,COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(C)C1(C(N)=O)CNC1.ClCCl.O=S(=O)(Cl)Cl>>COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(C)C1(C(N)=O)CN(S(C)(=O)=O)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150023913A1,C=CCC(CO[C@](C)(C=C)COC(=O)c1ccccc1)OCc1ccccc1>>C[C@]1(COC(=O)c2ccccc2)C=CCC(OCc2ccccc2)CO1,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,ClCCl,,,,test
US20050277652A1,CN(C)C(=O)Nc1cc(Oc2ccc(N)cc2F)ccn1.NC(=O)Cc1ccccc1.O=C(Cl)C(=O)Cl>>CN(C)C(=O)Nc1cc(Oc2ccc(NC(=O)NC(=O)Cc3ccccc3)cc2F)ccn1,,CN(C)C=O,ClCCCl,CCOC(C)=O,,test
US20010027194A1,C=CCBr.Cc1cccc(O)c1>>C=CCOc1cccc(C)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140350019A1,COc1c(C)cc(-c2cccc(F)c2)cc1C(=O)O.Nc1c(F)ccc(O)c1F>>COc1c(C)cc(-c2cccc(F)c2)cc1C(=O)Nc1c(F)ccc(O)c1F,,C1CCOC1,,O=S(Cl)Cl,O=C([O-])O.[Na+],test
US20100249096A1,C[C@@H](N(C(=O)[O-])C(C)(C)C)C1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1.Cl>>C[C@@H](N)C1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1.Cl,,CO,,,,test
US20100158863A1,CN(C)C=Nc1ccc(-c2ccc(F)c(F)c2)cc1C#N.Nc1ccc(-c2c[nH]nn2)cc1>>Fc1ccc(-c2ccc3ncnc(Nc4ccc(-n5cncn5)cc4)c3c2)cc1F,,CC(=O)O,,,,test
US20060264429A1,COC=Cc1cccc2c1OCC(=O)N2C>>CN1C(=O)COc2c(CC=O)cccc21,,C1CCOC1,Cl,,,test
US20140011799A1,NC1CC1.O=C(OCc1ccccc1)[C@H](Cc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1)NS(=O)(=O)N1CCOC1=O>>O=C(OCc1ccccc1)[C@H](Cc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1)NS(=O)(=O)NC1CC1,,CC#N,,,,test
US20080070935A1,CC(=O)c1cnc(N)c2ccc(F)cc12.NO>>CC(=NO)c1cnc(N)c2ccc(F)cc12,,CO,O,Cl,CC(=O)[O-].[Na+],test
US04484942,CC(C)(N)c1ccc(F)cc1.Cc1ccccc1CC(=O)Cl>>Cc1ccccc1CC(=O)NC(C)(C)c1ccc(F)cc1,,CCN(CC)CC,,c1ccccc1,,test
US20040014742A1,CC(=O)Cl.CCOC(=O)C[C@H](N)c1cccc(F)c1>>CCOC(=O)C[C@H](NC(C)=O)c1cccc(F)c1,,ClCCl,,Cl,O,test
US20070254910A1,CN1CCN(c2cccc3nc(CN(C)[C@H]4CCCc5cccnc54)c(C=O)n23)CC1.C[Mg]Br>>CC(O)c1c(CN(C)[C@H]2CCCc3cccnc32)nc2cccc(N3CCN(C)CC3)n12,,C1CCOC1,ClCCl,,,test
US04965284,O=[N+]([O-])c1ccc2c(c1)S(=O)(=O)c1cc(F)ccc1-2>>Nc1ccc2c(c1)S(=O)(=O)c1cc(F)ccc1-2,[Pd],CC(=O)O,,C1COCCO1,,test
US20090156612A1,CCOC(=O)Cl.N[C@H]1CCCC[C@@H]1n1cnc(C(=O)N2CCN(Cc3ccccc3)C[C@H]2Cc2ccccc2)c1-c1ccccc1>>CCOC(=O)N[C@H]1CCCC[C@@H]1n1cnc(C(=O)N2CCN(Cc3ccccc3)C[C@H]2Cc2ccccc2)c1-c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US04567267,O=C(O)[C@@H]1CCCN1.O=C1C(c2ccccc2)SC2Sc3ccccc3N12>>O=C(O)[C@@H]1CCCN1C(=O)C(Sc1nc2ccccc2s1)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US06432980B1,CC(=O)O.O=C(OCc1ccccc1)N1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1>>CC(=O)O.Fc1ccc(-c2[nH]c(C3CCNCC3)cc2-c2ccncc2)cc1,[Pd],,,,,test
US20070117800A1,COc1ccc(CNCc2ccc(-c3ccnc(Cl)n3)s2)cc1.O=C(Cl)c1ccccc1>>COc1ccc(CN(Cc2ccc(-c3ccnc(Cl)n3)s2)C(=O)c2ccccc2)cc1,,ClCCl,,CCN(CC)CC,c1ccncc1,test
US20120283297A1,CC(C)Oc1ccc(C(=O)O)cc1C#N.CCOC(=O)CCCn1ncc2cc(C(=N)NO)c(OC)cc21>>CCOC(=O)CCCn1ncc2cc(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)c(OC)cc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160229853A1,NC1CSC1.O=[N+]([O-])c1cc(Cl)ccc1F>>O=[N+]([O-])c1cc(Cl)ccc1NC1CSC1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20140148433A1,Fc1ccccc1Cn1nc(-c2ccc3nccnc3n2)c2cccnc21>>Fc1ccccc1Cn1nc(-c2ccc3c(n2)NCCN3)c2cccnc21,O=[Pt]=O,CO,,,,test
US20130324528A1,CC1CO1.Cc1ccc(F)c(-c2cc(Nc3ccnc4cn[nH]c34)c(C)cn2)n1>>Cc1ccc(F)c(-c2cc(Nc3ccnc4cn(C[C@H](C)O)nc34)c(C)cn2)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04537616,CC(C)C1CC(=O)CC(=O)C1.CCOC1=NCCC1>>CC(C)C1CC(=O)C(=C2CCCN2)C(=O)C1,,CC(C)O,,,,test
US04383945,CC(C)(OC(=O)OCc1ccc([N+](=O)[O-])cc1)[C@@H]1C(=O)N2[C@@H]1CCOC2(C)C>>CC(C)(OC(=O)OCc1ccc([N+](=O)[O-])cc1)[C@@H]1C(=O)N[C@@H]1CCO,,CC(=O)O,O,,,test
US20030092677A1,CC(C)(C)OC(=O)Nc1ccc(-c2cccc(F)c2F)cc1NC(=O)CC(=O)c1cccc(-n2ccnn2)c1>>O=C1CC(c2cccc(-n3ccnn3)c2)=Nc2ccc(-c3cccc(F)c3F)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090036431A1,CC(O)=S.OCc1cc(CO)cc(CO)c1>>CC(=O)SCc1cc(CO)cc(CO)c1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05654316,O=C1CC(c2ccc(Cl)c(Cl)c2)CC(=O)O1.c1ccc2c(c1)CCNC2>>O=C(O)CC(CC(=O)C1NCCc2ccccc21)c1ccc(Cl)c(Cl)c1,,ClCCl,,CCN(CC)CC,,test
US20100041698A1,COc1ccc2nc(Cl)c(C=O)cc2c1.COc1ccccc1[Mg]Br>>COc1ccc2nc(Cl)c(C(O)c3ccccc3OC)cc2c1,,C1CCOC1,,O,,test
US20140249129A1,N#Cc1ccc(C2NC(=O)N(c3cccc(C(F)(F)F)c3)C3=C2C(=O)CCC3)cc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>N#Cc1ccc(C2C3=C(CCCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C(=O)Oc2ccc([N+](=O)[O-])cc2)cc1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20160102104A1,CC(C)(C)OC(=O)N(CCO)CCOCCOc1ccccc1NC(=O)c1nc(Br)cnc1N.Cc1cc(B(O)O)ccc1S(N)(=O)=O>>CNS(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3OCCOCCN(CCO)C(=O)OC(C)(C)C)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20150203483A1,CC1(C)OC(=O)C(C)(Cc2ccc(OC(F)(F)F)cc2)C(=O)O1>>CC(Cc1ccc(OC(F)(F)F)cc1)C(=O)O,,C1COCCO1,,Cl,,test
US20160024021A1,COC(=O)c1cc(CCc2cnc(Nc3ccnc(C)c3)nc2)c(F)c(OC)c1>>COc1cc(C(=O)O)cc(CCc2cnc(Nc3ccnc(C)c3)nc2)c1F,,CO,,[Na+].[OH-],,test
US20030199552A1,O=C(O)c1cc2cc3oc(=O)[nH]c3cc2o1.c1ccc(COC2CCNCC2)cc1>>O=C(c1cc2cc3oc(=O)[nH]c3cc2o1)N1CCC(OCc2ccccc2)CC1,,CCOCC,,,,test
US04271170,CCOC(=O)C(C)Br.O=Cc1cccnc1.Sc1ccc(Br)cc1>>CCOC(=O)C(C)Sc1ccc(C(O)c2cccnc2)cc1,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US04699647,CI.O=c1[nH]nc(-c2ccccc2SCc2ccccc2)o1>>Cn1nc(-c2ccccc2SCc2ccccc2)oc1=O,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20040014754A1,CC(C)(C)OC(=O)NCCCCn1c(-c2ccccc2)nc2c(N)nc3ccccc3c21>>NCCCCn1c(-c2ccccc2)nc2c(N)nc3ccccc3c21,,CO,,Cl,,test
US04529721,COC(=O)C1SC(=CC(=O)OC(C)(C)C)S1.ClSc1ccccc1>>COC(=O)C1SC(=C(Sc2ccccc2)C(=O)OC(C)(C)C)S1,,ClCCl,,c1ccncc1,,test
US20120184539A1,CC(C)=C(Cl)N(C)C.C[C@@]1(c2cccc(NC(=O)c3ccc(Br)cn3)n2)COCC(N)=N1.O=C(O)c1ccc(Br)cn1>>CC(C)(C)OC(=O)NC1=N[C@](C)(c2cccc(NC(=O)c3ccc(Br)cn3)n2)COC1,,ClCCl,,CCN(CC)CC,,test
US04486428,CCCCCCC(C)(C)c1ccc2c(c1)N(O)C(C)(C)C(CCN)C2.COc1cc(CNCCCNCCCCNCCCN)ccc1O.Cc1ccc(S(=O)(=O)Cl)cc1>>CCCCCCC(C)(C)c1cc(O)c2c(c1)NC(C)(C)C(CCNS(=O)(=O)c1ccc(C)cc1)C2,,ClCCl,,CCN(CC)CC,,test
US20050197331A1,N#Cc1cc([N+](=O)[O-])ccc1N.O=C(Cl)c1ccccc1>>Nc1ccc([N+](=O)[O-])cc1CNC(=O)c1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US06756378B2,CC#N.CCN(CC)CC.CCN=C=NCCCN(C)C.COC(=O)c1ccc(OC[C@@H]2C[C@H](N(C)C)CN2C(=O)OC(C)(C)C)cc1.Cl.ClCCl.O=C(O)C(F)(F)F.On1nnc2ccccc21>>COC(=O)c1ccc(OC[C@@H]2C[C@H](N(C)C)CN2C(=O)Cc2ccc(NC(=O)Nc3ccccc3Cl)c(OC)c2)cc1,,CC#N,ClCCl,C1CCOC1,,test
US20080207654A1,CCC(C)Br.CCCc1nc(C)n(-c2ccc(O)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1>>CCCc1nc(C)n(-c2ccc(OC(C)CC)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20040087552A1,COc1nn(C)c(C(F)(F)F)c1C1CCN(C(=O)OC(C)(C)C)CC1>>COc1nn(C)c(C(F)(F)F)c1C1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090197862A1,COC(=O)C(OC)OC.Cc1ccccc1CN>>COC(OC)C(=O)NCc1ccccc1C,,CCOC(C)=O,,,,test
US20040192698A1,COC(=O)c1ccc2nc(NC(C)C)c3n[nH]c(=O)n3c2c1>>CC(C)Nc1nc2ccc(CO)cc2n2c(=O)[nH]nc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140275084A1,CC(=O)OCBr.Fc1ccc(-c2c(-c3cc(-c4nn[nH]n4)ccn3)ncn2Cc2ccccc2Cl)cc1>>CC(=O)OCn1nnc(-c2ccnc(-c3ncn(Cc4ccccc4Cl)c3-c3ccc(F)cc3)c2)n1,,CN(C)C=O,,O,CC(C)(C)[O-].[K+],test
US20110306589A1,CC(C)OCCN.O=C(O)c1ccncc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1>>CC(C)OCCNC(=O)c1ccncc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1,,C1CCOC1,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060074111A1,CCCCNCc1ccc(OCC(=O)OCC)c(C)c1.COc1ccc(-c2ncnc(Cl)c2C)cc1>>CCCCN(Cc1ccc(OCC(=O)OCC)c(C)c1)c1ncnc(-c2ccc(OC)cc2)c1C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080200365A1,C=C1C(=O)CC(C)C12CC(C)CC(C)(C)C2.O=C(OO)c1cccc(Cl)c1>>CC1CC(C)(C)CC2(C1)C(C)CC(=O)C21CO1,,ClCCl,,,,test
US20110046378A1,COCCl.COCOc1ccc2c(=O)c(O)c(-c3ccc(OCc4ccccc4)c(OCOC)c3)oc2c1>>COCOc1ccc2c(=O)c(OCOC)c(-c3ccc(OCc4ccccc4)c(OCOC)c3)oc2c1,,CCOCC,ClCCl,CCN(C(C)C)C(C)C,,test
US20120065231A1,CCCN(CC1OCCO1)c1cc(Br)c(C#N)s1>>CCCN(CC=O)c1cc(Br)c(C#N)s1,,CO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20110053912A1,O=C(c1cnc(Cl)nc1C(F)(F)F)N1CCOCC1.Sc1cccc(Cl)c1>>O=C(c1cnc(Sc2cccc(Cl)c2)nc1C(F)(F)F)N1CCOCC1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20130085141A1,CC(C)(C)OC(=O)N1CCN2CC[C@@H](O)[C@H]2C1.Clc1ccc(Cl)nc1>>CC(C)(C)OC(=O)N1CCN2CC[C@@H](Oc3ccc(Cl)cn3)[C@H]2C1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20040110793A1,CCc1ccc(CCNC(=O)C2(Cc3ccccc3F)CCNCC2)cc1.O=C(O)CCc1ccc(F)cc1>>CCc1ccc(CCNC(=O)C2(Cc3ccccc3F)CCN(C(=O)CCc3ccc(F)cc3)CC2)cc1,,C1CCOC1,CCOCC,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20120309746A1,COC(OC)N(C)C.NO.Nc1ncc(Cl)cc1I>>ON/C=N\c1ncc(Cl)cc1I,,CC(C)O,,Cl,O=C([O-])O.[Na+],test
US05550134,CN1C(=O)CC[C@]2(C)c3ccc(S)cc3CC[C@@H]12.O=[N+]([O-])c1ccc(Br)nc1>>CN1C(=O)CC[C@]2(C)c3ccc(Sc4ccc([N+](=O)[O-])cn4)cc3CC[C@@H]12,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05028606,CCCC(O)c1ccc(NC(C)=O)cc1.O=C(n1ccnc1)n1ccnc1>>CCCC(c1ccc(NC(C)=O)cc1)n1ccnc1,,C1CCOC1,,,,test
US20100022515A1,CC(C)(C)OC(=O)N1CCc2cc(N)ccc2C1.CC(C)OC(=O)N1CCC(CCCOS(C)(=O)=O)CC1>>CC(C)OC(=O)N1CCC(CCCNc2ccc3c(c2)CCN(C(=O)OC(C)(C)C)C3)CC1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040122063A1,CCOC(=O)C1(NC2CC[C@@H](N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)[C@@H](N)C2)CC1.Cl>>CCOC(=O)C1(NC2CC[C@@H](N)[C@@H](N)C2)CC1.Cl,,ClCCl,,CCO,,test
US05144081,CC1(C)[C@@H]2CC[C@@]1(C)C(=O)C2.COc1ccc(OC)c(C=O)c1>>COc1ccc(OC)c(C=C2C(=O)C3(C)CCC2C3(C)C)c1,,C1CCCCC1,,O,C[O-].[Na+],test
US05144045,CCCCCCCCCCCCCCCCOCC(CSCCCCCCCCCCCCCCCC)C(=O)OCC>>CCCCCCCCCCCCCCCCOCC(CO)CSCCCCCCCCCCCCCCCC,,C1CCOC1,,O,[BH4-].[Li+],test
US20090286812A1,Cc1nn(C2CCN(C(=O)OC(C)C)CC2)c2ncnc(Cl)c12.Oc1cc(F)c(F)cc1F>>Cc1nn(C2CCN(C(=O)OC(C)C)CC2)c2ncnc(Oc3cc(F)c(F)cc3F)c12,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20070112037A1,CO.COc1ccc(-n2nc(N)cc2-c2ccc(OCc3ccccc3)cc2)cc1.NC=O>>COc1ccc(-n2nc(N(C)C)cc2-c2ccc(OCc3ccccc3)cc2)cc1,,CO,,[BH3-]C#N.[Na+],,test
US20080175814A1,Cc1cc(Nc2cccc(NC(=O)c3ccc(N)cc3)c2)nc(N)n1.Cl.Clc1ccnc2ccccc12>>Cc1cc(Nc2cccc(NC(=O)c3ccc(Nc4ccnc5ccccc45)cc3)c2)nc(N)n1.Cl,,O,,CCO,,test
US20050131001A1,CSc1cc(C)nc(SC)c1NC(=O)CCCBr.Sc1nc2ccccc2o1>>CSc1cc(C)nc(SC)c1NC(=O)CCCSc1nc2ccccc2o1,,CN(C)C=O,O,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US20120316161A1,CCCC(C(=O)OC)c1c(C)nc2nc(C(C)C)nn2c1Cl.Cc1ccc(B(O)O)cc1>>CCCC(C(=O)OC)c1c(C)nc2nc(C(C)C)nn2c1-c1ccc(C)cc1,,COCCOC,O,CCN(C(C)C)C(C)C,Cl,test
US20140088078A1,CCN1CCC[C@H]1CCc1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1C(=O)OC)OC[C@@H]1C[C@H]21>>CCN1CCC[C@H]1CCc1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)OC[C@@H]1C[C@H]21,,C1COCCO1,O,[Li+].[OH-],,test
US20070049618A1,NCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C(Cl)c1ccc(OC(F)(F)F)cc1>>O=C1CCC(N2C(=O)c3cccc(CNC(=O)c4ccc(OC(F)(F)F)cc4)c3C2=O)C(=O)N1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20090042852A1,CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)NS(=O)(=O)c3ccc(Cl)s3)C(CCC(=O)OC(C)(C)C)C2)nc1C(F)(F)F>>CCOC(O)c1cc(C#N)c(N2CCN(C(=O)NS(=O)(=O)c3ccc(Cl)s3)C(CCC(=O)O)C2)nc1C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US05153203,CC(C)(C)OC(=O)N1CCC(Oc2c(F)c(N)c3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1.Cl>>Cl.Nc1c(F)c(OC2CCNC2)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1,,CC(=O)O,,,,test
US20150252029A1,CN(C)C=O.CN1CCN(CCc2ccc(Br)cc2)CC1>>CN1CCN(CCc2ccc(C=O)cc2)CC1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20070185097A1,COc1cc(N2CCn3cc(Br)cc3C2=O)ccc1OCC(C)(C)O.c1ccc(SSc2ccccc2)cc1>>COc1cc(N2CCn3cc(Sc4ccccc4)cc3C2=O)ccc1OCC(C)(C)O,,C1CCOC1,,[Li]CCCC,,test
US20100261720A1,CC(=O)OC(C)=O.CCOC(=O)c1cc2ccc(Oc3ccc(N)cn3)cc2[nH]1>>CCOC(=O)c1cc2ccc(Oc3ccc(NC(C)=O)cn3)cc2[nH]1,,c1ccncc1,,O,,test
US20100278733A1,CC(=O)c1ccc([N+](=O)[O-])cc1.O=Cc1ccc(Br)cc1>>O=C(C=Cc1ccc(Br)cc1)c1ccc([N+](=O)[O-])cc1,,CCO,,[K+].[OH-],,test
US20080004271A1,COc1cc(-c2nc(NC3CC3)nc(O)c2C#N)ccc1C(F)(F)F.O=P(Cl)(Cl)Cl>>COc1cc(-c2nc(NC3CC3)nc(Cl)c2C#N)ccc1C(F)(F)F,CN(C)C=O,C1COCCO1,,,,test
US20080300242A1,COc1cc(N2CCC(N3CCN(CCS(C)(=O)=O)CC3)CC2)ccc1N.O=C(Nc1c(F)cccc1F)c1cccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)c1>>COc1cc(N2CCC(N3CCN(CCS(C)(=O)=O)CC3)CC2)ccc1Nc1nccc(-c2c(-c3cccc(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090075979A1,BrC(Br)(Br)Br.CCC(O)c1ccc(C(F)(F)F)cc1CN1C(=O)O[C@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H]1C>>CCC(Br)c1ccc(C(F)(F)F)cc1CN1C(=O)O[C@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H]1C,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110172223A1,C=CC(C)(C)S(=O)(=O)c1cccc(C(F)(F)F)c1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C1CO1)S(=O)(=O)c1cccc(C(F)(F)F)c1,,ClCCCl,,,,test
US20150259343A1,C=O.NCCN1CCC(C2CCC2)c2ccccc21>>c1cc2c3c(c1)C(C1CCC1)CCN3CCNC2,,CCO,,O=C(O)C(F)(F)F,,test
US20040138251A1,C1COCCN1.COc1cc(Nc2c(C#N)cnc3sc(-c4ccc(C=O)cc4)cc23)c(Cl)cc1Cl>>COc1cc(Nc2c(C#N)cnc3sc(-c4ccc(CN5CCOCC5)cc4)cc23)c(Cl)cc1Cl,,CN(C)C=O,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090163512A1,CC(C)(C)OC(=O)N1CCN(c2ccc(Cl)cc2C=O)CC1.O=C1Cc2ccc(Cl)cc2N1>>CC(C)(C)OC(=O)N1CCN(c2ccc(Cl)cc2/C=C2\C(=O)Nc3cc(Cl)ccc32)CC1,,CO,,C1CCNC1,,test
US20160237071A1,CSc1ncn(Cc2ccc(C(F)(F)F)s2)c(=O)n1.FC(F)Oc1ccc2c(c1)CCNC2>>O=c1nc(N2CCc3cc(OC(F)F)ccc3C2)ncn1Cc1ccc(C(F)(F)F)s1,,C1COCCO1,,CCN(C(C)C)C(C)C,Cl,test
US20030069223A1,O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1.O=S(Cl)Cl>>O=C(Cl)[C@@H]1CCCN1C(=O)OCc1ccccc1,,ClCCl,,,,test
US20130150360A1,O=[N+]([O-])c1cc(Br)c2ncccc2c1>>Nc1cc(Br)c2ncccc2c1,[Fe],O,,CCO,[Cl-].[NH4+],test
US06048910,CC(=O)O.CO.CO[Si](C)(CCCOCC1CO1)OC.CO[Si](C)(OC)OC.O>>C=C(C)C(=O)OC.C=CC(=O)OCCCC,,CO,,,,test
US20150175621A1,CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc(CNC(=O)c3cc4ccncc4o3)nc2)CC1>>O=C(NCc1ccc(S(=O)(=O)C2CCNCC2)cn1)c1cc2ccncc2o1,,O=C(O)C(F)(F)F,,,,test
US20160206616A1,COC(=O)C1=C(CBr)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl.O=C(O)CC[C@H]1CC(F)(F)CN1>>COC(=O)C1=C(CN2CC(F)(F)C[C@@H]2CCC(=O)O)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20120142705A1,COc1ccc2c(c1)C(=O)C(=O)N2C(CC1CCCC1)C(=O)O.Cn1ccc(N)n1>>COc1ccc2c(c1)C(=O)C(=O)N2C(CC1CCCC1)C(=O)Nc1ccn(C)n1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20100120760A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc3c(c12)CC(C)O3.O=[N+]([O-])O>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc([N+](=O)[O-])c3c(c12)CC(C)O3,,ClC(Cl)Cl,,,,test
US20030176454A1,Cc1ncc(-c2cccc(NC(=S)NC(=O)c3ccccc3)c2)n1C>>Cc1ncc(-c2cccc(NC(N)=S)c2)n1C,,CO,,Cl,[Na+].[OH-],test
US20030078251A1,CCCOc1c(C(=O)OCC)oc2ccc(NC(=O)C[C@H]3O[C@H](c4cccc(OC)c4OC)c4cc(Cl)ccc4N(CC(C)(C)COC(C)=O)C3=O)cc12>>CCCOc1c(C(=O)O)oc2ccc(NC(=O)C[C@H]3O[C@H](c4cccc(OC)c4OC)c4cc(Cl)ccc4N(CC(C)(C)CO)C3=O)cc12,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US04233302,CN(C)Cc1ccc(CSCCN)o1.CSC(=C[N+](=O)[O-])SC.O=C(O)C(=O)O>>CSC(=C[N+](=O)[O-])NCCSCc1ccc(CN(C)C)o1.O=C(O)C(=O)O,,C1COCCO1,,,,test
US20100041635A1,COC(=O)c1ccc(F)c(B(O)O)c1.O=C1Nc2ccc(Cl)cc2C1=Cc1ccc(Br)o1>>COC(=O)c1ccc(F)c(-c2ccc(C=C3C(=O)Nc4ccc(Cl)cc43)o2)c1,,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130217668A1,CC(C)(O)CN1CCN(C(=O)OCc2ccccc2)CC1.Cl>>CC(C)(O)CN1CCNCC1.Cl,[Pd],CCO,CCOC(C)=O,C1COCCO1,,test
US20130196998A1,Fc1ncccc1I.OCC1=CCN(Cc2ccccc2)CC1>>Ic1cccnc1OCC1=CCN(Cc2ccccc2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20150038528A1,CC(C)(C)OC(=O)C(C)(C)CN.CCOC(=O)c1ncc2cc(Oc3ccc(Cl)c(F)c3)ccc2c1O>>CC(C)(C)OC(=O)C(C)(C)CNC(=O)c1ncc2cc(Oc3ccc(Cl)c(F)c3)ccc2c1O,,CCO,,,,test
US20120077993A1,CC(=O)OC1=C(Br)C(C)OC1(C)C>>CC1OC(C)(C)C(=O)C1Br,,ClC(Cl)Cl,,BrBr,,test
US20130137675A1,CC(=O)C(=NNc1ccccc1OC(C)(C)C)C(=O)CC(=O)COCc1ccccc1>>CC(=O)c1nn(-c2ccccc2OC(C)(C)C)c(COCc2ccccc2)cc1=O,,CC#N,,CCN(CC)CC,,test
US20100273755A1,COC(=O)Cc1ccc(NCC(=O)CCN2CCC(OC(=O)Nc3ccccc3-c3ccccc3)CC2)cc1>>O=C(O)Cc1ccc(NCC(=O)CCN2CCC(OC(=O)Nc3ccccc3-c3ccccc3)CC2)cc1,,CC#N,O,Cl,[Li+].[OH-],test
US20080139564A1,CN(C)CCC(=O)c1ccc(OCCCN2CCCCC2)cc1>>CN(C)CCC(O)c1ccc(OCCCN2CCCCC2)cc1,,CCO,O,[BH4-].[Na+],,test
US20110230461A1,CC(=O)OCc1ccc2c(n1)OCCO2>>OCc1ccc2c(n1)OCCO2,,CO,,[Na+].[OH-],,test
US04335127,CC(=O)OC(C)=O.Nc1ccccc1C(=O)NCCN1CCC(C(=O)c2ccc(F)cc2)CC1>>Cc1nc2ccccc2c(=O)n1CCN1CCC(C(=O)c2ccc(F)cc2)CC1,,Cc1ccccc1,,,,test
US20090143372A1,CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(CN)c4)cc23)CC1.O=S(=O)(Cl)C1CC1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4cccc(CNS(=O)(=O)C5CC5)c4)cc23)CC1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,,test
US06130229,CSC(=NC#N)N1CCN(C2c3ccc(Cl)cc3SCc3cccnc32)CC1.NCc1ccc2c(c1)OCO2>>N#CN=C(NCc1ccc2c(c1)OCO2)N1CCN(C2c3ccc(Cl)cc3SCc3cccnc32)CC1,,ClCCl,O,,,test
US20120202785A1,CC(C)(C)OC(=O)N[C@@H](COCc1ccccc1)c1nc2ccc(F)cc2n1-c1ccccn1>>N[C@@H](COCc1ccccc1)c1nc2ccc(F)cc2n1-c1ccccn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140056849A1,CC(C)C(=O)OCCl.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(Cl)cc4)cc23)c1F>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2cn(COC(=O)C(C)C)c3ncc(-c4ccc(Cl)cc4)cc23)c1F,,CN(C)C=O,,CCN(CC)CC,,test
US05616586,BrBr.CCOC(=O)C(=O)N1CCc2ccccc21>>CCOC(=O)C(=O)N1CCc2cc(Br)ccc21,[Fe],ClCCl,,,,test
US20040110767A1,COc1ccc(S(=O)(=O)N(Cc2ccc(OC3CCCCO3)cc2)c2ccc(OCCN3CCCC3)cc2)cc1.Cl>>COc1ccc(S(=O)(=O)N(Cc2ccc(O)cc2)c2ccc(OCCN3CCCC3)cc2)cc1.Cl,,CCO,,C1COCCO1,,test
US04086219,COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)OCc1ccccc1.Cl>>COC(=O)[C@H](CC(C)C)NC(=O)[C@H](N)Cc1ccccc1.Cl,[Pd],CO,,[H][H],,test
US20090005426A1,CC(=O)Oc1cccc(C(=O)O)c1.NCc1cccs1>>CC(=O)Oc1cccc(C(N)=O)c1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US04956462,CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](N)[C@H]2SC1.O=C(O)c1cc(S)n2nc(CO)nc2n1>>NC1C(=O)N2C(C(=O)O)=C(CSc3cc(C(=O)O)nc4nc(CO)nn34)CS[C@H]12,,CC#N,,N,O,test
US20040229900A1,CCN(CC)CC.CCNC(=O)N1CC2CC(CN(CC(N)COc3ccc(C#N)cc3)C2)C1.O=C(Cl)N1CCOCC1>>CCNC(=O)N1CC2CC(CN(CC(COc3ccc(C#N)cc3)NC(=O)N3CCOCC3)C2)C1.N,,ClCCl,,O=C([O-])O.[Na+],,test
US20140121198A1,CO[C@@H]1C[C@@H](N)CC[C@@H]1CC#N.O=[N+]([O-])c1cnc2ccsc2c1Cl>>CO[C@@H]1C[C@@H](Nc2c([N+](=O)[O-])cnc3ccsc23)CC[C@@H]1CC#N,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US05108486,BrCCBr.Nc1ccc([N+](=O)[O-])cc1O>>O=[N+]([O-])c1ccc2c(c1)OCCN2,,CN(C)C=O,,[H-].[Na+],,test
US20160068494A1,CC(C)(C)[Si](OCC1CC(=O)C1)(c1ccccc1)c1ccccc1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)[Si](OCC1C=C(OS(=O)(=O)C(F)(F)F)C1)(c1ccccc1)c1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20080300242A1,CC(C)[C@H]1CN(Cc2ccccc2)C(=O)C(=O)N1>>CC(C)[C@H]1CN(Cc2ccccc2)CCN1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100173933A1,NC(=O)c1c(F)ccc(OCC2=Cc3cc(C4=CCCCC4)ccc3C2)c1F>>NC(=O)c1c(F)ccc(OCC2=Cc3cc(C4CCCCC4)ccc3C2)c1F,[Pd],CO,,,,test
US20110207738A1,N#Cc1ccc(S(=O)(=O)N2CCc3cc(-c4ccc(C(F)(F)F)nc4)ccc32)cc1.NO>>N=C(NO)c1ccc(S(=O)(=O)N2CCc3cc(-c4ccc(C(F)(F)F)nc4)ccc32)cc1,,C1CCOC1,CO,CCN(CC)CC,Cl,test
US20070123527A1,Brc1cccc2[nH]ccc12.O=C=NS(=O)(=O)Cl>>N#Cc1c[nH]c2cccc(Br)c12,,CC#N,,,,test
US20100184815A1,COC(c1ccc(Cn2cc(COC(=O)c3ccc(SC(C)(C)C(=O)OC(C)(C)C)cc3)nn2)cc1)(C(F)(F)F)C(F)(F)F>>COC(c1ccc(Cn2cc(COC(=O)c3ccc(SC(C)(C)C(=O)O)cc3)nn2)cc1)(C(F)(F)F)C(F)(F)F,,C1COCCO1,,Cl,,test
US20070149561A1,CCn1cc(-c2ccnc3[nH]ccc23)c(-c2ccc(N)cc2)n1.O=C=Nc1ccccc1>>CCn1cc(-c2ccnc3[nH]ccc23)c(-c2ccc(NC(=O)Nc3ccccc3)cc2)n1,,c1ccncc1,,,,test
US20020094989A1,O=C1OC[C@H](Cc2ccccc2)N1C(=O)[C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccccc1>>OC[C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05391537,COC(=O)c1nc(N(C)C)ccc1Oc1nc(OC)cc(OC)n1.[K+]>>COc1cc(OC)nc(Oc2ccc(N(C)C)nc2C(=O)[O-])n1.[K+],,CO,,O,,test
US20120108582A1,C1=C(CNC(c2ccccc2)(c2ccccc2)c2ccccc2)OCCC1.OO>>OC1CCCOC1CNC(c1ccccc1)(c1ccccc1)c1ccccc1,,C1CCOC1,,[Na+].[OH-],,test
US20120053299A1,COc1cccc(CCc2cccc(OC)c2)c1>>Oc1cccc(CCc2cccc(O)c2)c1,,ClCCl,,BrB(Br)Br,,test
US20150291595A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=S(=O)(NC1(Br)C=CC=NC1)c1ccc(F)cc1F>>CC1(C)OB(C2=CC(O)(NS(=O)(=O)c3ccc(F)cc3F)CN=C2)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20120015958A1,COC(=O)c1coc(CN2CCNCC2)n1.O=C(Nc1ccc(C(=O)O)cc1)NC1CCC1>>COC(=O)c1coc(CN2CCN(C(=O)c3ccc(NC(=O)NC4CCC4)cc3)CC2)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20090130076A1,COC(=O)Cl.Nc1nc2c(-c3cccc(Cl)c3)cc(CO)cc2o1>>COC(=O)OCc1cc(-c2cccc(Cl)c2)c2nc(N)oc2c1,,C1CCOC1,O,c1ccncc1,,test
US04268510,COc1ccc([N+](=O)[O-])c(CO)c1>>COc1ccc(N)c(CO)c1,O=[Pt],CCO,,[H][H],,test
US20160145276A1,Brc1ccccc1CC#Cc1ccccc1.C#Cc1ccccc1>>C(#Cc1ccccc1)Cc1ccccc1C#Cc1ccccc1,[Cu]I,CCN(CC)CC,,,,test
US20160000760A1,CC(C)=O.CC1(NS(=O)(=O)c2ccc(-c3c(Cl)cc(Nc4n[nH]c(N)n4)cc3C(F)(F)F)cc2)CNC1.Cl>>CC(C)N1CC(C)(NS(=O)(=O)c2ccc(-c3c(Cl)cc(Nc4n[nH]c(N)n4)cc3C(F)(F)F)cc2)C1.Cl,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20100152160A1,CC(C)(C)OC(=O)N(CC/C=C/c1ccc(F)cc1)Cc1ccccc1>>Fc1ccc(/C=C/CCNCc2ccccc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070032485A1,CCOC(=O)N1c2ccc(OC)nc2[C@@H](Nc2ncc(COCCOC3CCCCO3)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC>>CCOC(=O)N1c2ccc(OC)nc2[C@@H](Nc2ncc(COCCO)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC,,CO,,Cl,O=C([O-])O.[Na+],test
US05703052,CCOCO[C@H]1CC[C@@]2(C)[C@H](C1)C(=O)C[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1C[C@@H]1O[C@]3(CC[C@@H](C)CO3)[C@@H](C)[C@@H]12>>CC1CC[C@@]2(OC1)O[C@H]1C[C@H]3[C@@H]4CC(=O)C5CCCC[C@]5(C)[C@H]4CC[C@]3(C)[C@H]1[C@@H]2C,Cl,C1CCOC1,CO,[Na+].[OH-],,test
US06150373,O=C1c2ccccc2C(=O)N1CCc1ccc(N2C(=O)N(c3ccc(Cl)cc3Cl)Cc3cnc(Nc4ccccc4)nc32)cc1>>NCCc1ccc(N2C(=O)N(c3ccc(Cl)cc3Cl)Cc3cnc(Nc4ccccc4)nc32)cc1,,CO,ClCCl,NN,O,test
US20060009493A1,CN1CCNCC1.O=C1Cc2cc(S(=O)(=O)Cl)ccc2N1>>CN1CCN(S(=O)(=O)c2ccc3c(c2)CC(=O)N3)CC1,,O,,,,test
US20150232469A1,CN(C)C=O.Nc1cnncc1N.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2cnncc2[nH]c1=O,,CN(C)C=O,,C1CCOC1,,test
US20120230951A1,Brc1ccc(-c2ncc([C@@H]3CCCN3)[nH]2)cc1.COC(=O)N[C@H](C(=O)O)C(C)C>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1cnc(-c2ccc(Br)cc2)[nH]1)C(C)C,,CCOC(C)=O,CN(C)C=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US06028116,COc1ccc2c(c1)C(CC(=O)O)=C(C)/C2=C/c1ccc(SC)cc1.O=C(Cl)C(=O)Cl>>COc1ccc2c(c1)C(CC(=O)Cl)=C(C)/C2=C/c1ccc(SC)cc1,,C1CCOC1,,,,test
US20060142336A1,CC(C)(C)[Si](C)(C)OC1CCNCC1.CS(=O)(=O)Cl>>CC(C)(C)[Si](C)(C)OC1CCN(S(C)(=O)=O)CC1,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20050234044A1,C1CCNCC1.O=Cc1ccc2c(c1)OCC[C@H]2NC(=O)CC1CCCCN1S(=O)(=O)c1cccc(C(F)(F)F)c1>>O=C(CC1CCCCN1S(=O)(=O)c1cccc(C(F)(F)F)c1)N[C@@H]1CCOc2cc(CN3CCCCC3)ccc21,,CC(=O)N(C)C,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04367238,C=CCc1cccc(Sc2ccccc2C)c1O>>CC=Cc1cccc(Sc2ccccc2C)c1O,,CO,,[K+].[OH-],,test
US20150018335A1,CC(C)(C)OC(=O)N1CCN(Cc2ccc(N3CCOCC3)cc2F)CC1>>Fc1cc(N2CCOCC2)ccc1CN1CCNCC1,,ClCCl,,Cl,,test
US20040097498A1,CCOc1ccc(N)cc1-c1nn2c(C3CCCC3)nc(C)c2c(=O)[nH]1.COc1ccc(CC(=O)Cl)cc1OC>>CCOc1ccc(NC(=O)Cc2ccc(OC)c(OC)c2)cc1-c1nn2c(C3CCCC3)nc(C)c2c(=O)[nH]1,,C1CCOC1,,c1ccncc1,,test
US20070197512A1,COC(=O)CCN1C(=O)C(C(C)C)Oc2ccc(C(F)(F)F)cc21>>CC(C)C1Oc2ccc(C(F)(F)F)cc2N(CCC(=O)O)C1=O,,CO,,[Na+].[OH-],,test
US20040209886A1,COC(=O)c1cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4OC)cc3)c2c1C>>COc1ccccc1Oc1ccc(Nc2c(C#N)cnn3cc(C(=O)O)c(C)c23)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20110201628A1,Clc1nc(Cl)c2cccnc2n1.Cn1cnc(N)c1>>Cn1cnc(Nc2nc(Cl)nc3ncccc23)c1,,CCO,,Cl,,test
US07074801B1,COCOc1ccc(Br)cc1F.CSC>>COCOc1ccc(SC)cc1F,,C1CCOC1,O,[Li]CCCC,[Cl-].[NH4+],test
US05326905,Cc1ccc(OCC2(C)CCCCC2)cc1.O=C1CCC(=O)N1Br>>CC1(COc2ccc(CBr)cc2)CCCCC1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20090069326A1,CI.O=Cc1c(Cl)cc(O)cc1Cl>>COc1cc(Cl)c(C=O)c(Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(C2CCC(=O)CC2)c2ncnn12.CCOC(=O)CP(=O)(OCC)OCC>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(C2CCC(=CC(=O)OCC)CC2)c2ncnn12,,C1CCOC1,,[H-].[Na+],,test
US20100197683A1,CCCCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(C2CCOCC2)c2ncnn12.O=C([O-])O.[NH3+]O>>CCCCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(C2CCOCC2)c2ncnn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20110046147A1,COc1ccc(B(O)O)cc1.COc1cccc(-c2ccc(Br)cc2)c1>>COc1ccc(-c2ccc(-c3cccc(OC)c3)cc2)cc1,,CCCCCC,CCOC(C)=O,,,test
US20080312226A1,CC(C)(C)OC(=O)N1CCN(c2nc(-c3cccc(C(F)(F)F)c3)cs2)CC1>>FC(F)(F)c1cccc(-c2csc(N3CCNCC3)n2)c1,,CCOC(C)=O,,Cl,,test
US20060258860A1,CCN1CCN(C)C(c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2C)C1>>CN1CCNCC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C,,ClCCl,O=C(O)C(F)(F)F,,,test
US20080234237A1,CC(C)(C)OC(=O)N1CCC(N2CCCCc3cc(NC(=N)c4cccs4)ccc32)C1>>N=C(Nc1ccc2c(c1)CCCCN2C1CCNC1)c1cccs1,,CO,,Cl,,test
US20080214511A1,Nc1ccc2c(c1)CC1(C2)C(=O)Nc2ncccc21.OCn1nnc2ccccc21>>CNc1ccc2c(c1)CC1(C2)C(=O)Nc2ncccc21,,CCO,CN(C)C=O,[BH4-].[Na+],,test
US20030176477A1,COC(=O)c1snc(Cl)c1Cl.NCC(O)CO>>O=C(NCC(O)CO)c1snc(Cl)c1Cl,,CO,,CCOC(C)=O,,test
US05108994,CCOP(=O)(CSC(CO)COn1cnc2c(N)ncnc21)OCC>>Nc1ncnc2c1ncn2OCC(CO)SCP(=O)(O)O,,ClCCl,,C[Si](C)(C)Br,,test
US07250410B2,COc1cc2c(cc1OC)N(C)C(=O)CN=C2Cl.OB(O)c1ccccc1>>CCCN1C(=O)CN=C(Cl)c2cc(OC)c(OC)cc21,,CN(C)C=O,,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20050245592A1,COc1c(N2CCOCC2)cc(C(C)=O)cc1C(C)(C)C.O=C1CCC(=O)N1Br>>COc1c(N2CCOCC2)cc(C(=O)CBr)cc1C(C)(C)C,,C1CCOC1,CCN(CC)CC,CCOCC,,test
US20050272699A1,Cc1cc(C(F)(F)F)n(-c2ccc(C=O)cc2)n1.N#CCc1cc(F)ccc1F>>Cc1cc(C(F)(F)F)n(-c2ccc(C=C(C#N)c3cc(F)ccc3F)cc2)n1,,CCO,,[K+].[OH-],,test
US20010012857A1,N#CCBr.NCCC(c1ccccc1)c1ccccc1>>N#CCNCCC(c1ccccc1)c1ccccc1,,CC#N,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20090324569A1,CI.O=[N+]([O-])c1cccc(O)c1Br>>COc1cccc([N+](=O)[O-])c1Br,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20120190649A1,CC(C)(C)[C@H]1CC[C@@H](O)CC1.N#Cc1ccc2cc(O)ccc2c1>>CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3cc(C#N)ccc3c2)CC1,,Cc1ccccc1,O,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050148624A1,COC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1CC1CCNCC1.O=C1CCC(=O)O1>>COC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1CC1CCN(C(=O)CCC(=O)O)CC1,,C1CCOC1,,CCN(CC)CC,Cl,test
US20060030613A1,C=CC[Si](C)(C)C.COC(=O)c1ccc(C(C)(C)OC)cc1>>C=CCC(C)(C)c1ccc(C(=O)OC)cc1,Cl[Ti](Cl)(Cl)Cl,,,ClCCl,,test
US04820821,CCN=C=S.N=c1ccn(-c2ccccc2)nc1>>CCNC(=S)C1C=CN(c2ccccc2)NC1=N,,CC(C)=O,,CCN(CC)CC,Cl,test
US20020165251A1,CC(C)(C)OC(=O)N1CCN(c2cccc3c2cc(I)n3S(=O)(=O)c2ccccc2)CC1.OB(O)c1ccccc1>>CC(C)(C)OC(=O)N1CCN(c2cccc3c2cc(-c2ccccc2)n3S(=O)(=O)c2ccccc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20050070718A1,COc1ccc(S(=O)(=O)N2C(=O)C(O)(c3sccc3C)c3cc(Cl)ccc32)c(OC)c1.O=C=Nc1ccc(Cl)cc1>>COc1ccc(S(=O)(=O)N2C(=O)C(OC(=O)Nc3ccc(Cl)cc3)(c3sccc3C)c3cc(Cl)ccc32)c(OC)c1,CN(C)c1ccncc1,Cc1ccccc1,,,,test
US04039676,Cc1ccc(S(=O)(=O)OCCC2Cc3ccccc3O2)cc1.OC1(c2ccccc2)CCNCC1>>OC1(c2ccccc2)CCN(CCC2Cc3ccccc3O2)CC1,,CC(=O)CC(C)C,,O=C([O-])[O-].[Na+].[Na+],,test
US20160152561A1,NS(=O)(=O)c1cccc(NC(=O)c2cc(C(F)(F)F)ccc2F)c1.Oc1ccc(F)cc1>>NS(=O)(=O)c1cccc(NC(=O)c2cc(C(F)(F)F)ccc2Oc2ccc(F)cc2)c1,,CCCCCC,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20130303551A1,Cn1ncc(C(=O)Nc2ccc(Br)cc2)c1NC(=O)C[C@@H]1CCN(C(=O)C2CC2)C1>>Cn1ncc2c(=O)n(-c3ccc(Br)cc3)c(C[C@@H]3CCN(C(=O)C4CC4)C3)nc21,Cl[Ti](Cl)(Cl)Cl,ClCCCl,,,,test
US20100144806A1,COC(=O)C1CC1c1ccc(O)cc1.Cc1cc(OCC2(C)COC2)cc(C)c1-c1cccc(CO)c1>>COC(=O)C1CC1c1ccc(OCc2cccc(-c3c(C)cc(OCC4(C)COC4)cc3C)c2)cc1,,CCCCCC,Cc1ccccc1,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20090134384A1,BrBr.Cc1ccc(-c2c3ccccc3cc3ccccc23)c2ccccc12>>Cc1ccc(-c2c3ccccc3c(Br)c3ccccc23)c2ccccc12,,CCO,ClCCl,,,test
US20110275627A1,COC(=O)CCN(C(=O)c1c(C)c(C(=O)C(C)(C)C)c2cc(C(C)C)ccn12)c1ccccc1>>Cc1c(C(=O)C(C)(C)C)c2cc(C(C)C)ccn2c1C(=O)N(CCC(=O)O)c1ccccc1,,C1COCCO1,O,CC(=O)O,[Na+].[OH-],test
US03983111,CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)CN5CCOCC5)[C@@]4(C)CC(=O)[C@@H]32)C[C@@H]1O.O=C(O)CC(O)(CC(=O)O)C(=O)O>>CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)CN5CCOCC5)[C@@]4(C)CC(=O)[C@@H]32)C[C@@H]1O.O=C(O)CC(O)(CC(=O)O)C(=O)O,,CCO,,,,test
US20110190263A1,CCOC(OCC)c1ncc2c(n1)CCN(S(C)(=O)=O)C2.Cc1ccc(S(=O)(=O)O)cc1>>CS(=O)(=O)N1CCc2nc(C=O)ncc2C1.Cc1ccc(S(=O)(=O)O)cc1,,CC(C)=O,O,,,test
US20140309193A1,CC(C)(C)O.COc1ccc(-n2cc(OCc3ccccc3)c(OCc3ccccc3)c2C(=O)N(C)C)cc1.O=C=NS(=O)(=O)Cl>>COc1ccc(-n2c(C(=O)N(C)C)c(OCc3ccccc3)c(OCc3ccccc3)c2S(=O)(=O)NC(=O)OC(C)(C)C)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160009719A1,COC(=O)C1CCCN1C(=O)OC(C)(C)C.O=C1CCC(=O)N1Br>>COC(=O)c1c(Br)ccn1C(=O)OC(C)(C)C,,ClC(Cl)(Cl)Cl,,,,test
US20080096935A1,BrCc1ccc(-n2cccn2)cc1.CC1(C2CCCC2)Cc2cc(O)c(Cl)c(Cl)c2C1=O>>CC1(C2CCCC2)Cc2cc(OCc3ccc(-n4cccn4)cc3)c(Cl)c(Cl)c2C1=O,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140296208A1,COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Oc4ccccc4)c4ccccc34)n2)cc(OC)c1.Cc1nc2cc(C(C)(C)C)cc(N)c2o1>>COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)cc5nc(C)oc45)c4ccccc34)n2)cc(OC)c1,,C1CCOC1,,,,test
US20120270838A1,Cc1cc2[nH]c(=O)n(C(C)(C)C)c(=O)c2c(C)c1CCS(=O)(=O)N1CCC2(CC1)N=C(C1CCC(C)CC1)NC2=O>>Cc1cc2[nH]c(=O)[nH]c(=O)c2c(C)c1CCS(=O)(=O)N1CCC2(CC1)N=C(C1CCC(C)CC1)NC2=O,,CC(=O)O,,Br,,test
US20110015173A1,O=S(=O)(c1ccccc1)n1cc(-c2cc(Cl)nc(NC3CCCCC3)c2)c2cc(O)cnc21>>Oc1cnc2[nH]cc(-c3cc(Cl)nc(NC4CCCCC4)c3)c2c1,,C1COCCO1,,[Na+].[OH-],,test
US20040010009A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc([N+](=O)[O-])cc2C(=O)O)CC1.N>>CC(C)(C)OC(=O)N1CCC(Oc2ccc([N+](=O)[O-])cc2C(N)=O)CC1,,ClCCl,,CC(C)COC(=O)Cl,CCN(CC)CC,test
US20150203483A1,BrCCOCCBr.CNC(=O)N1N=C(c2ccc(N)cc2)c2cc(OC)ccc2C[C@@H]1C>>CNC(=O)N1N=C(c2ccc(N3CCOCC3)cc2)c2cc(OC)ccc2C[C@@H]1C,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,O,test
US05200412,COS(=O)(=O)OC.O=C(N[C@@H](Cc1ccc(O)cc1)C(=O)O)OCc1ccccc1>>COc1ccc(C[C@H](NC(=O)OCc2ccccc2)C(=O)O)cc1,,[Na+],[OH-],Cl,,test
US20150266864A1,CC1CCN(CCC(=CO)C(=O)c2ccc(F)cc2)CC1.Cl.NO>>CC1CCN(CCc2conc2-c2ccc(F)cc2)CC1.Cl,,CCO,,,,test
US20070185132A1,COCCl.O=[N+]([O-])c1cc(F)c(O)c(F)c1>>COCOc1c(F)cc([N+](=O)[O-])cc1F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20060074056A1,CC(C)(C)OC(=O)N1CCC(N)C1.O=C(Cl)c1cc2nccc(Oc3ccc([N+](=O)[O-])cc3F)c2s1>>CC(C)(C)OC(=O)N1CCC(NC(=O)c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)C1,,ClCCl,,,,test
US20130336920A1,CN(CC=O)C(=O)OCc1ccccc1.CNCCOCCOCCOCCN=[N+]=[N-]>>CN(CCOCCOCCOCCN=[N+]=[N-])CCN(C)C(=O)OCc1ccccc1,,C1CCOC1,CCOC(C)=O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130303492A1,CCOC(=O)c1cccc(N)c1.CSC(SC)=C(C#N)C(N)=O.NN>>CCOC(=O)c1cccc(Nc2n[nH]c(N)c2C(N)=O)c1,,CCO,,O,,test
US20140113931A1,N#Cc1ncc(N[C@@H]2CCCC[C@@H]2N)cc1Nc1ccc2cccnc2c1.OO>>NC(=O)c1ncc(N[C@@H]2CCCC[C@@H]2N)cc1Nc1ccc2cccnc2c1,,CCO,CS(C)=O,CC(=O)O,[Na+].[OH-],test
US20080031852A1,CI.CS(=O)(=O)Nc1ccc2ncsc2c1>>CN(c1ccc2ncsc2c1)S(C)(=O)=O,,C1CCOC1,,[H-].[Na+],,test
US20040138277A1,CCOC(=O)C(C)(Cc1ccc(OCc2ccccc2)cc1)Oc1ccc(C2CCCCC2)cc1>>CCOC(=O)C(C)(Cc1ccc(O)cc1)Oc1ccc(C2CCCCC2)cc1,[Pd],CCOC(C)=O,,,,test
US06242600B1,COC(=O)C[C@@H]1NCCN(CC(=O)OC(C)(C)C)C1=O.O=C(O)CCC(=O)N1CCN(c2ccccn2)CC1>>COC(=O)C[C@H]1C(=O)N(CC(=O)O)CCN1C(=O)CCC(=O)N1CCN(c2ccccn2)CC1,,CC#N,,CCN=C=NCCCN(C)C,Cl,test
US04251443,BrBr.CCC1N=C(c2ccccc2Cl)c2cc(N)ccc2N(C)C1=O>>CCC1N=C(c2ccccc2Cl)c2c(ccc(N)c2Br)N(C)C1=O,,Br,,O=C([O-])[O-].[Na+].[Na+],,test
US05134142,CI.CS(=O)(=O)c1ccc(-c2cc(C#N)nn2-c2ccc(N)cc2)cc1>>CNc1ccc(-n2nc(C#N)cc2-c2ccc(S(C)(=O)=O)cc2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160264554A1,Cc1[nH]c2ccccc2c1I.O=S(=O)(Cl)c1ccccc1>>Cc1c(I)c2ccccc2n1S(=O)(=O)c1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US20140187554A1,CC(C)(C)OC(=O)N1CCNCC1.CS(=O)(=O)OCCc1ccc(Br)cc1>>Brc1ccc(CCN2CCNCC2)cc1,,CC#N,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150353497A1,CC1CCCC(O)(CNC(=O)c2c(Cl)ccc3nc(C4=CC(=O)CC4)ccc23)C1>>CC1CCCC(O)(CNC(=O)c2c(Cl)ccc3nc(C4CCC(=O)C4)ccc23)C1,[Pd],,,CC[SiH](CC)CC,,test
US20130079324A1,CCOC(=O)CP(=O)(OCC)OCC.O=CC1CC1>>CCOC(=O)/C=C/C1CC1,,C1CCOC1,,[H-].[Na+],,test
US06825200B1,CC(C)(C)OC(=O)N1CCNCC1.FC(F)(F)CCBr>>CC(C)(C)OC(=O)N1CCN(CCC(F)(F)F)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20140011807A1,COCCCn1nc(C)c2ccc([C@@H](C)N(C(=O)[C@H]3CN(C(=O)OC(C)(C)C)CCO3)C3CC3)cc21.Cl>>COCCCn1nc(C)c2ccc([C@@H](C)N(C(=O)[C@H]3CNCCO3)C3CC3)cc21.Cl,,ClC(Cl)Cl,,C1COCCO1,,test
US20040097581A1,CC1(C)CC(=O)CC(=O)C1.COc1ccc(C=O)cc1.N#CCC#N>>COc1ccc(C2C(C#N)=C(N)OC3=C2C(=O)CC(C)(C)C3)cc1,C1CCNCC1,CCO,,,,test
US20130331372A1,OCCCc1ccc(OCCCl)c(I)c1>>C=COc1ccc(CCCO)cc1I,,C1CCOC1,,Cl,CC(C)(C)[O-].[K+],test
US20060025589A1,CCOC(=O)C(C)Br.Nc1ccc(Oc2ccc(F)cc2)cc1>>CCOC(=O)[C@H](C)Nc1ccc(Oc2ccc(F)cc2)cc1,,CCO,,CC(=O)[O-].[Na+],,test
US20110301142A1,O=C(Cl)C(=O)Cl.O=C(O)c1cccc(Br)c1>>O=C(Cl)c1cccc(Br)c1,,ClCCl,,CN(C)C=O,,test
US20110003865A1,CCN(CC)c1nc(NCc2ccc(F)cc2)ccc1[N+](=O)[O-]>>CCN(CC)c1nc(NCc2ccc(F)cc2)ccc1N,[Ni],CCO,O,,,test
US20160046649A1,CNCCOc1ccccc1C(C)C.COC(=O)c1ccccc1N=C=O>>COC(=O)c1ccccc1NC(=O)N(C)CCOc1ccccc1C(C)C,,ClCCl,O,CCN(CC)CC,Cl,test
US04771046,Cl.N#CCCl.ON=C1CCNCC1>>Cl.N=C(CCl)N1CCC(=NO)CC1,,CO,,[Na],,test
US20120010241A1,Cc1nn(-c2ccc(C#N)c(NCCC3(O)CCN(C)CC3)c2)c2cccc(-c3cnc4ccccc4c3)c12.OO>>Cc1nn(-c2ccc(C(N)=O)c(NCCC3(O)CCN(C)CC3)c2)c2cccc(-c3cnc4ccccc4c3)c12,,CS(C)=O,O,CCO,[Na+].[OH-],test
US06664256B1,CS(=O)(=O)c1ccc(-c2nnccc2-c2ccc(Cl)cc2)cc1.OO>>CS(=O)(=O)c1ccc(-c2n[n+]([O-])ccc2-c2ccc(Cl)cc2)cc1,,CC(=O)O,,,,test
US20060258862A1,CC(=O)O.Nc1ncc([N+](=O)[O-])c(NCCO)n1>>Nc1ncc2ncn(CCO)c2n1,[Fe],CC(=O)O,,CCOCC,,test
US20130274260A1,COC(=O)c1ccc(Cc2cccc(F)c2)c(F)c1>>O=C(O)c1ccc(Cc2cccc(F)c2)c(F)c1,,CCO,,Cl,[Na+].[OH-],test
US20150284391A1,C=CCCC(C)C[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)O.C=C[C@@H]1C[C@]1(N)C(=O)NS(=O)(=O)C1(CF)CC1.CCN(C(C)C)C(C)C>>C=CCCC(C)C[C@@H](C)[C@H](NC(=O)OCCCC)C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@]1(C(=O)NS(=O)(=O)C2(CF)CC2)C[C@H]1C=C,,ClCCl,,Cl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110015181A1,CCOC(=O)c1cc(OS(=O)(=O)C(F)(F)F)cc(COC2CCCCO2)n1.FC1(F)CCNCC1>>CCOC(=O)c1cc(N2CCC(F)(F)CC2)cc(COC2CCCCO2)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20040132960A1,CC(=O)CCCO.COCCl>>COCOCCCC(C)=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120208815A1,CC(C)(C)OC(=O)Nc1cc(-c2ccncc2N)nc(C(F)(F)F)n1.Nc1ccc(Br)nc1C(=O)O>>CC(C)(C)OC(=O)Nc1cc(-c2ccncc2NC(=O)c2nc(Br)ccc2N)nc(C(F)(F)F)n1,,CN(C)C=O,O,ClCCCl,On1nnc2cccnc21,test
US20050137184A1,O=[N+]([O-])c1ccc(-c2ccc(O)cc2)cc1.OC1CN2CCC1CC2>>O=[N+]([O-])c1ccc(-c2ccc(OC3CN4CCC3CC4)cc2)cc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100249182A1,O=C(Nc1ccc(Oc2ccnc3c([N+](=O)[O-])cccc23)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1>>Nc1cccc2c(Oc3ccc(NC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)cc3)ccnc12,,CCO,,Cl[Sn]Cl,,test
US20050153978A1,CN1CCN(CCCNc2ccccc2N)CC1.Cc1nc(O)c2nonc2n1>>CN1CCN(CCCn2c(-c3nonc3N)nc3ccccc32)CC1,,CC(=O)O,,,,test
US04327032,O.O=C(O)CCCCC(=O)O.O[Al](O)O>>O=C([O-])CCCCC(=O)[O-].[Al+3].[OH-],,O,,,,test
US04937388,CCOc1ccc(C2(C(F)(F)F)CO2)cc1.SCc1cccc(Oc2ccccc2)c1>>CCOc1ccc(C(O)(CSCc2cccc(Oc3ccccc3)c2)C(F)(F)F)cc1,,CC(=O)O,CN(C)C=O,O,[H-].[Na+],test
US20090023720A1,CC(C)(C)OC(=O)NCCCCNc1c(N)c(Cl)nc2ccccc12.N#CBr>>CC(C)(C)OC(=O)NCCCCn1c(N)nc2c(Cl)nc3ccccc3c21,,CCO,,,,test
US20100240703A1,O=C1c2ccccc2C(=O)N1O.O=S(=O)(c1ccc(OC(F)(F)F)cc1)N1CCC(O)CC1>>O=C1c2ccccc2C(=O)N1OC1CCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)CC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160237090A1,C[C@H]1Cn2ncc(N3CC(Nc4ncccn4)CC3=O)c2CN1C(=O)OC(C)(C)C.O=C(Nc1cc(F)c(F)c(F)c1)Oc1ccccc1>>C[C@H]1Cn2ncc(N3CC(Nc4ncccn4)CC3=O)c2CN1C(=O)Nc1cc(F)c(F)c(F)c1,,ClCCl,O=C(O)C(F)(F)F,CCN(C(C)C)C(C)C,,test
US20030236297A1,CCCCCC(=O)OC(NC(=O)OC(C)(C)C)[C@H](C)C=Cc1ccc2ccsc2c1>>CCCCCC(=O)OC(NC(=O)OC(C)(C)C)[C@H](C)CCc1ccc2ccsc2c1,[Pd],CO,,,,test
US20100093694A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(OS(=O)(=O)C(F)(F)F)cc12.O=C(O)c1cc(Cl)cc(B(O)O)c1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(Cl)cc(C(=O)O)c3)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cl,O,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US20070281920A1,O=C1CC(c2ccc3[nH]ccc3c2)c2ccccc2CN1>>c1ccc2c(c1)CNCCC2c1ccc2[nH]ccc2c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120208814A1,CC(=O)N1c2ccc(-c3cn(CCO)nn3)cc2[C@H](N)C[C@@H]1C.CC(C)(C)[Si](C)(C)Cl>>CC(=O)N1c2ccc(-c3cn(CCO[Si](C)(C)C(C)(C)C)nn3)cc2[C@H](N)C[C@@H]1C,,CN(C)C=O,,c1c[nH]cn1,,test
US04258044,O=S(=O)(Cl)c1cc2nc(Cl)c(Cl)nc2cc1Cl.OCC(F)(F)F>>O=S(=O)(OCC(F)(F)F)c1cc2nc(Cl)c(Cl)nc2cc1Cl,,C1CCOC1,CCOCC,CCN(C(C)C)C(C)C,,test
US20030078251A1,CC(=O)Cl.COc1cccc([C@H]2O[C@H](CC(=O)NCCCOc3cccc(C(=O)O)c3)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC>>COc1cccc([C@H]2O[C@H](CC(=O)NCCCOc3cccc(C(=O)O)c3)C(=O)N(CC(C)(C)COC(C)=O)c3ccc(Cl)cc32)c1OC,,O,,CCOC(C)=O,c1ccncc1,test
US05990142,C=CCOc1ccc(C(=O)OCC)cc1>>C=CCc1cc(C(=O)OCC)ccc1O,,CCOC(C)=O,,CN(C)c1ccccc1,,test
US20030187026A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.NC(=O)c1cncc(Br)c1>>CC(=O)c1cncc(C(N)=O)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,,Cl,,test
US20040044043A1,CCS(=O)(=O)O.CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1>>CCS(=O)(=O)O.CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1,,CC(C)O,,,,test
US20120178765A1,COC(=O)c1cc(OCc2ccccc2C)cc(C(=O)O)c1>>COC(=O)c1cc(CO)cc(OCc2ccccc2C)c1,,C1CCOC1,,O,,test
US06235785B1,CCCc1c(O)cccc1O.COC(=O)c1ccc(F)cc1Br>>CCCc1c(O)cccc1Oc1cc(F)ccc1C(=O)OC,[Cu]I,c1ccncc1,,CC(C)(C)[O-].[K+],,test
US04851418,O=C1NC(=O)c2ccccc21.O[C@H]1CCN(Cc2ccccc2)C1>>O=C1c2ccccc2C(=O)N1[C@@H]1CCN(Cc2ccccc2)C1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110269738A1,CCOC(=O)C1CCN(CCc2cccc(-c3nsc(-c4cnc(OC(C)C)c(Cl)c4)n3)c2CC)CC1>>CCc1c(CCN2CCC(C(=O)O)CC2)cccc1-c1nsc(-c2cnc(OC(C)C)c(Cl)c2)n1,,CC(C)O,O,[Na+].[OH-],,test
US04938791,Clc1ccc(OCC2(C3(Cl)CC3)CO2)cc1.c1nc[nH]n1>>OC(COc1ccc(Cl)cc1)(Cn1cncn1)C1(Cl)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04822793,CC(C)=NO.O=[N+]([O-])c1ccc(F)cc1>>CC(C)=NOc1ccc([N+](=O)[O-])cc1,,C1CCOC1,O,CS(C)=O,[H-].[Na+],test
US20090239854A1,CN1CCC(=O)CC1.Cc1ccc(NN)cc1.O=C(O)C1CCN(C(=O)CCBr)CC1>>Cc1ccc2c(c1)c1c(n2CCC(=O)N2CCC(C(=O)O)CC2)CCN(C)C1,,CCN(CC)CC,,Cl,,test
US20140275172A1,CCc1cc2cc(Cl)cc(C=O)c2o1>>CCc1cc2cc(Cl)cc(CO)c2o1,,CO,,[BH4-].[Na+],,test
US20110294780A1,CC1(C)OCC(CN2C(=O)S/C(=C\c3ccc4c(cnn4Cc4ccc(Cl)cc4C(F)(F)F)c3)C2=O)O1>>O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(Cl)cc3C(F)(F)F)c2)C(=O)N1CC(O)CO,,C1COCCO1,,Cl,,test
US20030130213A1,COC(=O)c1nccn([C@@H]2O[C@H](CO)[C@H]3OC(C)(C)O[C@H]32)c1=O.O=P([O-])(OCc1ccccc1)OCc1ccccc1>>COC(=O)c1nccn([C@@H]2O[C@H](COP(=O)(OCc3ccccc3)OCc3ccccc3)[C@H]3OC(C)(C)O[C@H]32)c1=O,,c1ccncc1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090312369A1,CN[C@@H](C)[C@@H](O)c1ccccc1.O=C(Cl)CCCCCl>>C[C@@H]([C@@H](O)c1ccccc1)N(C)C(=O)CCCCCl,,C1CCOC1,,CCN(CC)CC,O,test
US20040242884A1,CNCC(O)c1ccc2c(c1)OCO2.Cc1c(CCl)sc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12>>Cc1c(CN(C)CC(O)c2ccc3c(c2)OCO3)sc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,,test
US20120245345A1,COc1ccc2ncc(Cl)c(C#N)c2n1.OCc1ccccc1>>COc1ccc2ncc(OCc3ccccc3)c(C#N)c2n1,,C1CCOC1,,CCOC(C)=O,[H-].[Na+],test
US05196408,CC(C)N.CCOC(=O)Cl>>CCOC(=O)NC(C)C,,CCOCC,,,,test
US20100010010A1,NCC1CCC(C(=O)O)CC1>>NCC1CCC(CO)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110034542A1,CCCCCCCCCCCCCCBr.NC(O)CCO>>CCCCCCCCCCCCCCNC(CO)CO,,CCO,,CCN(C(C)C)C(C)C,,test
US20130029971A1,CN1CCCN(C(=O)CC2CCN(c3ncc(Br)cc3NC(=O)c3cccc(Cl)c3)CC2)CC1.OB(O)c1cccnc1>>CN1CCCN(C(=O)CC2CCN(c3ncc(-c4cccnc4)cc3NC(=O)c3cccc(Cl)c3)CC2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04067723,CO.Cc1ccccc1CC(=O)CCC(=O)O>>COC(=O)CCC(=O)Cc1ccccc1C,,CCOCC,,Cl,,test
US20100137299A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1Nc2cccc(Br)c2C12COc1cc3c(cc12)OCO3>>CC(C)(C)OC(=O)N1C(=O)C2(COc3cc4c(cc32)OCO4)c2c(Br)cccc21,,C1CCOC1,O,[Na+].[OH-],,test
US20130059834A1,ClCCCBr.OC1CNC1>>OC1CN(CCCCl)C1,,CC#N,CCOC(C)=O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20100048564A1,CC(C)(C)OC(=O)NCc1cc(Cl)ccc1[N+](=O)[O-].CCc1ccc(O)cc1>>CCc1ccc(Oc2ccc([N+](=O)[O-])c(CNC(=O)OC(C)(C)C)c2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20100029637A1,O=C1CN2C=CC=CC2=N1.O=Cc1cccc2ccccc12>>O=C1N=C2C=CC=CN2C1=Cc1cccc2ccccc12,,CCO,,Br,,test
US20020049204A1,CC1(C)OC(=O)Nc2ccc(-c3coc(C=O)c3)cc21.NO>>CC1(C)OC(=O)Nc2ccc(-c3coc(C=NO)c3)cc21,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20060276496A1,CCOC(=O)c1ccc(NN=C2CCCNC2=O)cc1>>CCOC(=O)c1ccc2[nH]c3c(c2c1)CCNC3=O,,O,,O=CO,,test
US20090030038A1,CC(C)(O)C(=O)Nc1cccc2c1CC[C@H](N(Cc1ccccc1)Cc1ccccc1)C2>>CC(C)(O)C(=O)Nc1cccc2c1CC[C@H](N)C2,,CO,,O=C[O-].[NH4+],,test
US20110135668A1,C1CCNCC1.Cc1cc(Nc2nc(Nc3ccccc3S(=O)(=O)C(C)C)c3c(C)n[nH]c3n2)c(OC(C)C)cc1C1CCN(C(=O)CBr)CC1>>Cc1cc(Nc2nc(Nc3ccccc3S(=O)(=O)C(C)C)c3c(C)n[nH]c3n2)c(OC(C)C)cc1C1CCN(C(=O)CN2CCCCC2)CC1,,CN(C)C=O,,,,test
US20110112135A1,CCC(=O)CBr.Nc1ncccc1Cl>>CCc1cn2cccc(Cl)c2n1,,CCO,,O=C([O-])O.[Na+],,test
US20110144105A1,CC(C)CC=O.O=S(=O)(c1ccccc1)n1ccc2cccnc21>>CC(C)CC(O)c1cc2cccnc2n1S(=O)(=O)c1ccccc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20090215743A1,COc1cccc(C2OC(CC(=O)N3CCC(C(=O)OC(C)(C)C)C3)c3nnc(C(C)C)n3-c3ccc(Cl)cc32)c1OC>>COc1cccc(C2OC(CC(=O)N3CCC(C(=O)O)C3)c3nnc(C(C)C)n3-c3ccc(Cl)cc32)c1OC,,ClCCl,,O=C(O)C(F)(F)F,,test
US04605434,CP(C)(=O)CN.O=[N+]([O-])c1ccc(Oc2ccc(C(F)(F)F)cn2)cc1[N+](=O)[O-]>>CP(C)(=O)CNc1cc(Oc2ccc(C(F)(F)F)cn2)ccc1[N+](=O)[O-],,Cc1ccccc1,,,,test
US20050245563A1,CC(C)(C)OC(=O)NCCCn1c(=O)c2cnn(C3CCCCO3)c2c2cc(Cl)ccc21>>NCCCn1c(=O)c2c[nH]nc2c2cc(Cl)ccc21,,O,,O=C(O)C(F)(F)F,,test
US20080312286A1,C1CCOC1.CC1(C2CCCC2)Cc2cc(OCc3ccc(C(N)=O)cc3)c(Cl)c(Cl)c2C1=O.CN(C)C=O>>CC(=O)NC(=O)c1ccc(COc2cc3c(c(Cl)c2Cl)C(=O)C(C)(C2CCCC2)C3)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20100222349A1,CC(C)(C)OC(=O)N1CCC(C=O)CC1.CCCCc1cc(OC2CCNCC2)c2ncccc2c1>>CCCCc1cc(OC2CCN(CC3CCN(C(=O)OC(C)(C)C)CC3)CC2)c2ncccc2c1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20150274740A1,CCOC(=O)CC(=O)c1ccc2[nH]nnc2c1.Nc1nc(-c2ccc(Cl)c(Cl)c2)n[nH]1>>O=c1cc(-c2ccc3[nH]nnc3c2)[nH]c2nc(-c3ccc(Cl)c(Cl)c3)nn12,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040092512A1,O=[N+]([O-])c1cc(F)cc(Br)c1O>>Nc1cc(F)cc(Br)c1O,,CCO,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US04076709,COC(=O)C1=C(O)c2sccc2S(=O)(=O)N1C.Nc1nccs1>>CN1C(C(=O)Nc2nccs2)=C(O)c2sccc2S1(=O)=O,,Cc1ccccc1C,,,,test
US20100137612A1,CSc1ccc(C(=O)CC(O)(c2cc(Cl)cc(Cl)c2)C(F)(F)F)cc1>>CSc1ccc(C(=O)C=C(c2cc(Cl)cc(Cl)c2)C(F)(F)F)cc1,,Cc1ccccc1,,O=S(Cl)Cl,c1ccncc1,test
US20040209932A1,Cc1cccc(-c2nc(CO[C@H]3CCC[C@@H](OCCOc4ccccc4B4OC(C)(C)C(C)(C)O4)C3)c(C)o2)c1>>Cc1cccc(-c2nc(CO[C@H]3CCC[C@@H](OCCOc4ccccc4B(O)O)C3)c(C)o2)c1,,C1CCOC1,,Cl,,test
US20120010188A1,NC(=O)c1ccc(N)nc1.O=C(CBr)c1ccc(F)cc1F>>NC(=O)c1ccc2nc(-c3ccc(F)cc3F)cn2c1,,CCO,,ClCCl,[Na+].[OH-],test
US20120178765A1,C1CCOC1.CC(C)OC(=O)/N=N/C(=O)OC(C)C.COC(=O)c1cc(O)cc(/C=C/c2ccc(F)cc2)c1>>CCC(COC)Oc1cc(/C=C/c2ccc(F)cc2)cc(C(=O)OC)c1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20080194535A1,C=CCBr.COc1ccc2c(c1)C(N=[N+]=[N-])C(O)C2>>C=CCO[C@@H]1Cc2ccc(OC)cc2[C@H]1N=[N+]=[N-],,CN(C)C=O,,O,[H-].[Na+],test
US20160002188A1,Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCN(C(=O)C3(NC(=O)OC(C)(C)C)CC3)CC2)c(F)c1>>Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCN(C(=O)C3(N)CC3)CC2)c(F)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080153812A1,COC(=O)c1ccc(OCCO)cc1.COc1cc(CCc2cc(N)n(C(=O)OC(C)(C)C)n2)cc(OC)c1>>COc1cc(CCc2cc(NC(=O)c3ccc(OCCO)cc3)n[nH]2)cc(OC)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20050131019A1,CN(C)C(OC(C)(C)C)OC(C)(C)C.O=C(O)c1ncccc1O>>CC(C)(C)OC(=O)c1ncccc1O,,Cc1ccccc1,,,,test
US20020103211A1,CC(=O)O[C@H](C)CCCCn1c(=O)c2[nH]c(Br)nc2n(C)c1=O.CC(C)(C)OC(=O)NCCCO>>CC(=O)O[C@H](C)CCCCn1c(=O)c2c(nc(Br)n2CCNC(=O)OC(C)(C)C)n(C)c1=O,,ClCCCl,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160046583A1,NCc1ccccc1.O=C(O)c1ccc2cncc(Br)c2c1>>O=C(NCc1ccccc1)c1ccc2cncc(Br)c2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06187777B1,CNCc1ccco1.Cc1nc(Cl)c2nc(-c3ccccc3)cc-2[nH]1>>Cc1nc(N(C)Cc2ccco2)c2nc(-c3ccccc3)cc-2[nH]1,,O,,O=C([O-])[O-].[K+].[K+],,test
US06376491B1,Cc1c(C(=O)NCCC2CCCCC2)oc2cccc(OCCCBr)c12.NCc1cccnc1>>Cc1c(C(=O)NCCC2CCCCC2)oc2cccc(OCCCNCc3cccnc3)c12,,CCOC(C)=O,CN1CCCC1=O,,,test
US20080255060A1,C#CCBr.OCCOCc1ccccc1>>C#CCOCCOCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20130087772A1,Brc1ccccn1.CC(C)(C)c1ccc(B(O)O)cc1>>CC(C)(C)c1ccc(-c2ccccn2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[K+].[K+],test
US20100174065A1,CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)OCCNC4)no2)cc1Cl.CCOC(=O)CCBr>>CCOC(=O)CCN1CCOc2cc(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)ccc2C1,,CCOC(C)=O,O,CCN(C(C)C)C(C)C,,test
US20090069288A1,C=CC(=O)OC.CC(C)Nc1ccc(-c2cc(C(=O)Nc3ccc(C(C)(C)N)cc3)no2)cc1Cl>>COC(=O)CCNC(C)(C)c1ccc(NC(=O)c2cc(-c3ccc(NC(C)C)c(Cl)c3)on2)cc1,,CO,,,,test
US06200995B1,O=[N+]([O-])c1cc(C(F)(F)F)ccc1F.Oc1cncc(Cl)c1>>O=[N+]([O-])c1cc(C(F)(F)F)ccc1Oc1cncc(Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04791139,O=C(O)CC(=O)O.O=Cc1cccc(Oc2ccccc2)c1>>O=C(O)/C=C/c1cccc(Oc2ccccc2)c1,,O,c1ccncc1,C1CCNCC1,Cl,test
US20160016908A1,CC(=O)N1c2ccc(Br)cc2[C@H](NC(=O)OCc2ccccc2)[C@@H](C)[C@@H]1C.CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1>>CC(=O)N1c2ccc(C3=CCN(C(=O)OC(C)(C)C)CC3)cc2[C@H](NC(=O)OCc2ccccc2)[C@@H](C)[C@@H]1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020035266A1,Cc1nnnn1-c1ccc(Br)cc1[N+](=O)[O-]>>Cc1nnnn1-c1ccc(Br)cc1N,[Zn],CO,,O,[Cl-].[NH4+],test
US20040132752A1,C1CCNC1.O=c1n(-c2ccc(Oc3ccccc3)cc2)ccn1-c1ccc(OCCBr)c(Cc2ccccc2)c1>>O=c1n(-c2ccc(Oc3ccccc3)cc2)ccn1-c1ccc(OCCN2CCCC2)c(Cc2ccccc2)c1,,CC#N,,[I-].[Na+],,test
US20150005232A1,Cc1nc(Cl)ncc1Br.O[C@@H]1CCNC1>>Cc1nc(N2CC[C@@H](O)C2)ncc1Br,,CCO,,CCN(C(C)C)C(C)C,Cl,test
US20080262050A1,OCc1ccc(OCc2ccccc2)cc1O>>O=Cc1ccc(OCc2ccccc2)cc1O,O=[Mn]=O,CO,ClCCl,,,test
US06350749B1,Cc1cc(=O)n(C)c2c1C(=O)CC(c1ccsc1)C2.Cl.N=C(N)NN>>Cc1cc(=O)n(C)c2c1C(=NNC(=N)N)CC(c1ccsc1)C2.Cl,,CCO,,Cl,,test
US20130131039A1,Cc1n[nH]cc1-c1nc(-c2ccc(N3CCOCC3)cc2)cc2nccn12.N#CC=CC1CCCC1>>Cc1nn(C(CC#N)C2CCCC2)cc1-c1nc(-c2ccc(N3CCOCC3)cc2)cc2nccn12,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20100105679A1,Cl.O=c1cc(OCc2ccccc2)ccn1-c1ccc2c(cnn2CCN2CCCC2)c1>>Cl.O=c1cc(OCc2ccccc2)ccn1-c1ccc2c(cnn2CCN2CCCC2)c1,,CCOC(C)=O,CCOCC,,,test
US20110144131A1,CC(C)N1CCC(c2nc3cc(-c4ccc(F)cc4F)nc(Cl)n3n2)CC1.Nc1nc(NC2CCCNC2)ccc1C(=O)C(F)(F)F>>CC(C)N1CCC(c2nc3cc(-c4ccc(F)cc4F)nc(N4CCCC(Nc5ccc(C(=O)C(F)(F)F)c(N)n5)C4)n3n2)CC1,,CS(C)=O,,CCN(C(C)C)C(C)C,Cl,test
US20100075973A1,CCOC(=O)c1ncn2c1[C@@H](C)N(C1CCCC1)c1nc(Cl)ncc1-2.COc1cc(C(=O)O)ccc1N>>CCOC(=O)c1ncn2c1[C@@H](C)N(C1CCCC1)c1nc(Nc3ccc(C(=O)O)cc3OC)ncc1-2,Cl,CC(C)O,,,,test
US20080207654A1,CCCc1nc(C)c(-c2ccc3c(c2)CCC(C)(C)O3)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCc1nc(C)c(-c2ccc3c(c2)CCC(C)(C)O3)c(=O)n1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,O,,CS(C)=O,[Cl-].[Na+],test
US20160237095A1,COc1cccc2c1CN(C(=O)OC(C)(C)C)C2>>COc1cccc2c1CNC2,,CCOC(C)=O,Cl,,,test
US20110053936A1,COC(=O)c1ccc(C)c(-c2ccc3c(c2)NC(=O)C32CCCC2)c1.NN>>Cc1ccc(C(=O)NN)cc1-c1ccc2c(c1)NC(=O)C21CCCC1,,CCO,,O,,test
US20100256363A1,C=CC[Mg]Br.O=C(CCCl)c1ccc(F)cc1>>C=CCC(O)(CCCl)c1ccc(F)cc1,,C1CCOC1,,,,test
US06013658,CC(C)(C)OC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](Cc1ccc2ccccc2c1)c1nnnn1CCc1ccccc1>>N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](Cc1ccc2ccccc2c1)c1nnnn1CCc1ccccc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US05436350,CCBr.CC[C@@H](C(=O)[O-])[C@H](CO)Cc1cncn1C>>CCOC(=O)[C@@H](CC)[C@H](CO)Cc1cncn1C,,CS(C)=O,,O,,test
US20100197609A1,CN.N#Cc1c(Cl)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1ccc(OCCO)cc1>>CNc1nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c(-c2ccc(OCCO)cc2)c1C#N,,C1CCOC1,,O,,test
US07151075B2,CC1=NOC(c2c(S(C)(=O)=O)ccc(C(=O)Cl)c2Cl)C1.Cn1nccc1O>>CC1=NOC(c2c(S(C)(=O)=O)ccc(C(=O)c3cnn(C)c3O)c2Cl)C1,,COCCOC,,O,O=C([O-])[O-].[K+].[K+],test
US20070149577A1,COc1ncc(C#N)cc1-c1ccc(CNC(=O)OC(C)(C)C)cc1>>COc1ncc(C#N)cc1-c1ccc(CN)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06194410B1,COCCc1cc(Cl)n2nc(SC)c(S(=O)(=O)c3ccccc3)c2n1.N>>COCCc1cc(N)n2nc(SC)c(S(=O)(=O)c3ccccc3)c2n1,,CN(C)C=O,CO,,,test
US20140073627A1,CNCc1ccc(CN2CCC(OC)CC2)cc1.COC(=O)c1nnc(CN(C)S(=O)(=O)c2c(C)cc(OC)cc2C)o1>>COc1cc(C)c(S(=O)(=O)N(C)Cc2nnc(C(=O)N(C)Cc3ccc(CN4CCC(OC)CC4)cc3)o2)c(C)c1,,ClCCCl,,C[Al](C)C,,test
US05658491,CCCCCCCCc1cnc(-c2ccc(OCCCOCC(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)OC(F)(F)F)cc2)nc1.CCCCCCCOc1cnc(-c2ccc(O)cc2)nc1>>CCCCCCCOc1cnc(-c2ccc(OCCCOCC(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)OC(F)(F)F)cc2)nc1,,CN(C)C=O,,,,test
US20140066424A1,C1COCCN1.Cc1nc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1ccnc(Cl)c1>>Cc1nc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1ccnc(N2CCOCC2)c1,,CS(C)=O,,,,test
US20100292212A1,CC(C)(C)CS(=O)(=O)Cl.CCOC(=O)C1(CCOC)CCNCC1>>CCOC(=O)C1(CCOC)CCN(S(=O)(=O)CC(C)(C)C)CC1,CN(C)c1ccncc1,ClCCl,,,,test
US20100331326A1,CC(C)(C)OC(=O)N1C(=O)CCc2ccc(Br)cc21.Cc1ccncc1N1CCNC1=O>>Cc1ccncc1N1CCN(c2ccc3c(c2)N(C(=O)OC(C)(C)C)C(=O)CC3)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20050171144A1,Cc1ccc(-c2nc3ccc(C)cn3c2CC(=O)O)cc1>>Cc1ccc(-c2nc3ccc(C)cn3c2CCO)cc1,,C1CCOC1,,,,test
US20050182045A1,CC(C)(C)OC(=O)N1CCC(O)CC1.Cc1nc2ccccc2c(=O)n1-c1ccc(O)cc1>>Cc1nc2ccccc2c(=O)n1-c1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100217000A1,C1=COCCC1.O=c1[nH]c2nc(SCc3cccc(F)c3F)nc(Cl)c2s1>>Fc1cccc(CSc2nc(Cl)c3c(n2)N(C2CCCCO2)CS3)c1F,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US04840963,COc1ccc2c(c1)cc(S(N)(=O)=O)n2S(=O)(=O)c1ccccc1>>COc1ccc2[nH]c(S(N)(=O)=O)cc2c1,,[Na+],[OH-],,,test
US20040010004A1,Cn1cc(CNc2ccccc2[N+](=O)[O-])c2ccccc21>>Cn1cc(CNc2ccccc2N)c2ccccc21,[Pd],CCO,,[H][H],,test
US05064833,CN.Cc1ccccc1Nc1nc(Cl)c2ccccc2n1>>CNc1nc(Nc2ccccc2C)nc2ccccc12.Cl,,CCO,,,,test
US20120083489A1,C/C=C/C(=O)OC.NCc1ccccc1>>COC(=O)CC(C)NCc1ccccc1,,CO,,,,test
US20110021489A1,CCO.O=C(N1CCOCC1)N1CC(c2ccc(C(F)(F)F)cc2)CC(c2nc(Cl)no2)C1>>CCOc1noc(C2CC(c3ccc(C(F)(F)F)cc3)CN(C(=O)N3CCOCC3)C2)n1,,CCO,,C,C[O-].[Na+],test
US20160194290A1,CC(C)C(CO)[C@@](C)(N[S@@](=O)C(C)(C)C)c1ccc(Br)c(Cl)c1>>CC(C)[C@@H](CO)C(C)(N)c1ccc(Br)c(Cl)c1,,CO,,Cl,,test
US20070197558A1,Nc1ccc(Cl)c([N+](=O)[O-])c1.Oc1ccc(S)cc1>>Nc1ccc(Sc2ccc(O)cc2)c([N+](=O)[O-])c1,,CS(C)=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20080262229A1,CCN(CC)C(=O)c1ccc(C(c2ccc(C(=O)OC)cc2)N2CCN(C(=O)OC(C)(C)C)CC2)cc1>>CCN(CC)C(=O)c1ccc(C(c2ccc(C(=O)O)cc2)N2CCN(C(=O)OC(C)(C)C)CC2)cc1,,CCO,O,[K+].[OH-],,test
US20090076046A1,CC(C)(C)OC(=O)N(Cc1ccc(Cl)cc1)c1ccc(C(O)c2c[nH]c3ncccc23)c(Cl)n1>>Clc1ccc(CNc2ccc(Cc3c[nH]c4ncccc34)c(Cl)n2)cc1,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20100292190A1,C#Cc1cnn(Cc2ccccc2)c1.CCOC(C)=O.COc1cc(I)cc(OC)c1OC.COc1ccc(I)c(O)c1OCc1ccccc1>>COc1cc(C(=O)c2c(-c3cnn(Cc4ccccc4)c3)oc3c(O)c(OC)ccc23)cc(OC)c1OC,,CCCCCC,,,,test
US20130267494A1,CC(C)(C)OC(=O)N1CCOC(c2ccc(Cl)c(Cl)c2)C(CNS(C)(=O)=O)C1.Cl>>CS(=O)(=O)NCC1CNCCOC1c1ccc(Cl)c(Cl)c1.Cl,,CCOC(C)=O,,,,test
US04213998,CC(=O)Oc1ccc(-c2ccc3oc(C(=O)O)cc3c2)cc1>>O=C(O)c1cc2cc(-c3ccc(O)cc3)ccc2o1,,CCO,,[K+].[OH-],,test
US20110028492A1,CC(C)(C)[Si](C)(C)OCCN[C@@H]1CC[C@@H](Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)CC1>>OCCN[C@@H]1CC[C@@H](Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20050131014A1,CCCC[Sn](C#C[Si](C)(C)C)(CCCC)CCCC.FC(F)(F)c1cccc2c(-c3cccc(Br)c3)c(Cc3ccccc3)cnc12>>C[Si](C)(C)C#Cc1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20090099156A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCC1CCCN(Cc2ccccc2)C1>>Cc1ccc(S(=O)(=O)OCC2CCCN(Cc3ccccc3)C2)cc1,,ClCCl,,CCN(CC)CC,,test
US20080255197A1,Cc1cccnc1CN(Cc1ncccc1C)C1CCNCC1.Nc1ccccc1O.O=C(Cl)Cl>>Cc1cccnc1CN(Cc1ncccc1C)C1CCN(C(=O)Nc2ccccc2O)CC1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20110275611A1,COc1ccc2[nH]c(C3CNCCO3)nc2c1.Nc1nc(Cl)cc(Cl)n1>>COc1ccc2[nH]c(C3CN(c4cc(Cl)nc(N)n4)CCO3)nc2c1,,CCO,,CCN(C(C)C)C(C)C,,test
US20120101086A1,Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(Cl)c3)s1)CCN(CCC(=O)OC(C)(C)C)C2.Cl>>Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(Cl)c3)s1)CCN(CCC(=O)O)C2.Cl,,C1CCOC1,Cl,,,test
US20050203078A1,Cc1cc(C(=O)O)ccc1N1CCOCC1=O.Cn1ccc(C(N)c2nc3cc(Cl)ccc3[nH]2)n1>>Cc1cc(C(=O)NC(c2ccn(C)n2)c2nc3cc(Cl)ccc3[nH]2)ccc1N1CCOCC1=O,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20100008881A1,CCCCCCC/C=C\CCC=O.NO>>CCCCCCC/C=C\C=CC=NO,,C1CCCCC1,,,,test
US20070197588A1,C/C=C1\C[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc2C1=O.N>>CC(N)C1C[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc2C1O,,C1CCOC1,,[BH4-].[Na+],,test
US04610982,CC(C)Cc1ccc(C(C)C(=O)O)cc1.O=C(Cl)C(=O)Cl>>CC(C)Cc1ccc(C(C)C(=O)Cl)cc1,,ClCCl,,,,test
US06218431B1,CCCCCC=Cc1c(C(C)C)nc(C(C)C)c(CO)c1-c1ccc(F)cc1>>CCCCCCCc1c(C(C)C)nc(C(C)C)c(CO)c1-c1ccc(F)cc1,,CCCCCC,CCOC(C)=O,,,test
US20040122029A1,COC(=O)C(Cc1cnc(Nc2ccccc2)nc1Nc1ccccc1)c1cc(OC)cc(OC)c1>>COc1cc(OC)cc(C2Cc3cnc(Nc4ccccc4)nc3N(c3ccccc3)C2=O)c1,,CCOC(C)=O,,CC(=O)O,O=S(=O)(O)O,test
US05470849,CC(C)(C)[Si](OCCC1=CCC(=O)N(c2ccccc2)CC1)(c1ccccc1)c1ccccc1.O=C(CBr)OCc1ccccc1>>CC(C)(C)[Si](OCCC1=CC(CC(=O)OCc2ccccc2)C(=O)N(c2ccccc2)CC1)(c1ccccc1)c1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20100210636A1,O=C1Nc2ccc(N3CCOC3=O)cc2C(CNC(=O)c2ccc(F)cc2)(C(F)(F)F)O1>>O=C1Nc2ccc(N3CCOC3=O)cc2[C@](CNC(=O)c2ccc(F)cc2)(C(F)(F)F)O1,,CCO,,CCCCCC,,test
US20120316161A1,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1Cl.Cc1ccc(B(O)O)cc1C>>CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc(C)c(C)c1,,COCCOC,O,CCN(C(C)C)C(C)C,,test
US20080242699A1,CC(=O)N[C@@H]1CC[C@@H](Oc2ccc3c(OCc4ccccc4)nccc3c2)CC1>>N[C@@H]1CC[C@@H](Oc2ccc3c(=O)[nH]ccc3c2)CC1,,Cl,,,,test
US20030092712A1,COc1ccc(CN)cc1.O=[N+]([O-])c1cc(Br)c(CBr)c(Br)c1>>COc1ccc(CNCc2c(Br)cc([N+](=O)[O-])cc2Br)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US03970704,COC(=O)C=C(C)/C=C\CC(C)CCC=C(C)C>>CC(C)=CCCC(C)C/C=C\C(C)=CC(=O)O,,O,,CO,[K+].[OH-],test
US20090227588A1,CCOC(=O)Cn1cc(C(=O)Cl)ccc1=O.Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)nc1>>CCOC(=O)Cn1cc(C(=O)Nc2ccc(-n3nc(-c4cccnc4)cc3C(F)(F)F)nc2)ccc1=O,,c1ccncc1,,,,test
US04011321,C=CCc1cc(C2=NNC(=O)CC2)ccc1OCC1CO1.CC(C)N>>C=CCc1cc(C2=NNC(=O)CC2)ccc1OCC(O)CNC(C)C,,CO,,,,test
US20060166985A1,CC(C)(C)OC(=O)NC(CC=O)C(=O)OCc1ccccc1.N[C@@H](Cc1ccncc1)C(=O)N1CCOCC1>>CC(C)(C)OC(=O)N[C@H]1CCN([C@@H](Cc2ccncc2)C(=O)N2CCOCC2)C1=O,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160229810A1,C#CCCCCOc1ccc(-c2nc3ccc(C=O)cc3[nH]2)cc1.CN1CCN(c2ccc([N+](=O)[O-])c(N)c2)CC1>>C#CCCCCOc1ccc(-c2nc3ccc(-c4nc5ccc(N6CCN(C)CC6)cc5[nH]4)cc3[nH]2)cc1,[Pd],CCO,O,,,test
US20100286132A1,CCOC(=O)c1ccc(O)cn1.OCc1c(-c2ccc(F)cc2)noc1/C=C/c1ccccc1>>CCOC(=O)c1ccc(OCc2c(-c3ccc(F)cc3)noc2/C=C/c2ccccc2)cn1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06030975,CO.CSc1nc(Cl)c2c(n1)CCC2>>COc1nc(SC)nc2c1CCC2,,CO,,C[O-].[Na+],,test
US05444057,O=C(O)c1cc([N+](=O)[O-])cc[n+]1[O-]>>Nc1ccnc(C(=O)O)c1,[Pd],CC(=O)O,,,,test
US20100173886A1,NC(=O)c1ccc(O)cc1.NCc1cccc2c(Cl)ccnc12>>NCc1cccc2c(Oc3ccc(C(N)=O)cc3)ccnc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120115841A1,CC1(c2cnc(CN=[N+]=[N-])s2)OCCO1>>CC1(c2cnc(CN)s2)OCCO1,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US03962320,CCOC(=O)C(Cc1ccc(C(=O)C(C)(C)C)cc1)(Cc1ccc(C(=O)C(C)(C)C)cc1)C(=O)OCC>>CC(C)(C)C(=O)c1ccc(CC(Cc2ccc(C(=O)C(C)(C)C)cc2)C(=O)O)cc1,,CCO,O,[K+].[OH-],,test
US05143912,NC1c2ccsc2-c2c(C(=O)O)cc(-c3ccccc3)c(=O)n21>>O=C(O)c1cc(-c2ccccc2)c(=O)n2c1-c1sccc1C2,[Zn],CC(=O)O,,O,,test
US20100105890A1,CO.OC[C@@H]1OC(O)[C@@H](O)[C@H]1O>>COC1O[C@@H](CO)[C@H](O)[C@@H]1O,O=S(=O)(O)O,CO,,CC(=O)[O-].[Na+],,test
US20030040482A1,BrCc1ccccc1.CC(C)(C)OC(=O)N[C@H](Cc1cccnc1)C(=O)O>>Br.CC(C)(C)OC(=O)N[C@H](CC1=CN(Cc2ccccc2)CC=C1)C(=O)O,,CC#N,,,,test
US05556977,CN.COC(=O)COc1ccc(C(=O)CN2CCN(c3ccncc3)CC2)cc1>>CNC(=O)COc1ccc(C(=O)CN2CCN(c3ccncc3)CC2)cc1,,CCO,,,,test
US05093356,CSc1ccc(/C=C2/C(C)=C(C=O)c3cc(F)ccc32)cc1.[Li]C>>CSc1ccc(/C=C2/C(C)=C(C(C)O)c3cc(F)ccc32)cc1,,C1CCOC1,,CCOCC,,test
US04640703,COC(=O)C(C)Oc1ccc(Oc2ncc(Cl)cc2F)cc1>>CC(Oc1ccc(Oc2ncc(Cl)cc2F)cc1)C(=O)O,,C1COCCO1,,Cl,[Na+].[OH-],test
US20160024017A1,CC(=O)N1CCC(Oc2ccc3[nH]nc(CN(C)CCN(C)C(=O)OC(C)(C)C)c3c2)CC1.O=C(O)C(F)(F)F>>CNCCN(C)Cc1n[nH]c2ccc(OC3CCN(C(C)=O)CC3)cc12.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20050277661A1,CCCC[Sn](C=COCC)(CCCC)CCCC.COC(=O)c1ncc2c(ccn2Cc2ccc(F)cc2)c1OS(=O)(=O)C(F)(F)F>>CCOC=Cc1c(C(=O)OC)ncc2c1ccn2Cc1ccc(F)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,[Cl-].[Li+],,test
US04375475,CC(=O)Cl.O=C1CC(O)CC(CCc2c(O)cc(Cl)cc2Cl)O1>>CC(=O)Oc1cc(Cl)cc(Cl)c1CCC1CC(O)CC(=O)O1,,CCOCC,,c1ccncc1,,test
US20120264790A1,COC(=O)c1ccc(/C=C/S(C)(=O)=O)c(OCCc2cccc(C)c2)c1>>COC(=O)c1ccc(CCS(C)(=O)=O)c(OCCc2cccc(C)c2)c1,[Pd],CO,,[H][H],,test
US05914328,CN1CCC[C@H]1COc1cc(Br)c[n+]([O-])c1.CO>>COc1cc(OC[C@@H]2CCCN2C)c[n+]([O-])c1,,CO,,C[O-].[Na+],,test
US20110201643A1,O=C(NOC1CCCCO1)c1ccc2c(c1)CNCC2.O=C(O)Cc1c[nH]c2ccccc12>>O=C(NOC1CCCCO1)c1ccc2c(c1)CN(C(=O)Cc1c[nH]c3ccccc13)CC2,,CCN(CC)CC,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
US20060025414A1,CC(C)(C)OC(=O)N1CCCC1C=O.CCOCC.CN(C)C=O.NO.O=C1CCC(=O)N1Cl.c1ccncc1>>CC(C)(C)OC(=O)N1CCCC1c1cc(-c2cccc(Cl)c2)on1,,CCOCC,CN(C)C=O,Cl,O,test
US05681958,Nc1ccccc1.O=C(CBr)Nc1ccccc1C(=O)O>>O=C(CNc1ccccc1)Nc1ccccc1C(=O)O,,CN(C)C=O,,[K+].[OH-],,test
US20070232631A1,O=C(NC(=O)c1ccccc1[N+](=O)[O-])Nc1ccc(Sc2ncc(Br)cn2)cc1.O=C(OO)c1cccc(Cl)c1>>O=C(NC(=O)c1ccccc1[N+](=O)[O-])Nc1ccc(S(=O)c2ncc(Br)cn2)cc1,,ClCCl,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090318475A1,COc1ccc(-c2c(-c3ccccc3F)oc3ncnc(O[C@H](C)CCCCC(=O)OC(C)(C)C)c23)cc1>>COc1ccc(-c2c(-c3ccccc3F)oc3ncnc(O[C@H](C)CCCCC(=O)O)c23)cc1,,C1COCCO1,Cl,,,test
US04789396,CCCC(=O)C1C(=O)CC(CCSc2ccc(C(F)(F)F)cn2)CC1=O.CCON>>CCCC(NOCC)=C1C(=O)CC(CCSc2ccc(C(F)(F)F)cn2)CC1=O,,CCO,O,Cl,[Na+].[OH-],test
US20060229326A1,COC(=O)c1cnc(OCc2nccn2C)c(Br)c1.OB(O)c1ccc(Cl)cc1>>COC(=O)c1cnc(OCc2nccn2C)c(-c2ccc(Cl)cc2)c1,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20080015187A1,COC(=O)c1nn2c(C)cn(C)c(=O)c2c1OCc1ccccc1>>COC(=O)c1nn2c(C)cn(C)c(=O)c2c1O,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20030207868A1,CC(=O)OCc1nc2cc(C#N)ccc2n1CCCCCCOC(=O)C(C)(C)C>>CC(=O)OCCCCCCn1c(CO)nc2cc(C#N)ccc21,,CCOC(C)=O,CO,O=C([O-])[O-].[K+].[K+],,test
US05159114,COC(=O)c1ccc(SC)c([N+](=O)[O-])c1>>CSc1ccc(C(=O)O)cc1[N+](=O)[O-],,CCO,O,CC(=O)O,[Na+].[OH-],test
US20090299008A1,C=CC(=O)OCCCC.CC(C)(C#N)N=NC(C)(C)C#N.CCCCCC.CN(C)C=O>>C=CC(=O)OC(C)CC.C=Cc1ccccc1,,ClC(Cl)Cl,,,,test
US20030036655A1,O=C(Nc1ccccc1)Nc1ccc(Cc2ccc(NC(=O)OCc3ccccc3)cc2)cc1>>Nc1ccc(Cc2ccc(NC(=O)Nc3ccccc3)cc2)cc1,[Pd],CCO,,,,test
US05985909,COC(=O)c1cc2ccc(C(=O)NCCc3ccccn3)cc2[nH]1>>O=C(NCCc1ccccn1)c1ccc2cc(C(=O)O)[nH]c2c1,,C1CCOC1,O,Cl,[K+].[OH-],test
US20120172291A1,CCOC(=O)[C@@]12C[C@H]1CC(F)(F)CCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@@H](OC(=O)c3ccccc3)C[C@H]1C(=O)N2>>CCOC(=O)[C@@]12C[C@H]1CC(F)(F)CCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@@H](O)C[C@H]1C(=O)N2,,CCO,,[K+].[OH-],,test
US20100048636A1,BrC(Br)(Br)Br.CC(C)(C)OC(=O)N1CCC[C@@H]([C@@H](O)c2cccc(F)c2)C1>>CC(C)(C)OC(=O)N1CCC[C@@H](C(Br)c2cccc(F)c2)C1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060287287A1,[N-]=[N+]=NCc1cc(Cl)cc(CN=[N+]=[N-])c1>>NCc1cc(Cl)cc(CN)c1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20100234357A1,C=C(C)CBr.Cc1cc(C)c(C)c(O)c1>>C=C(C)COc1cc(C)cc(C)c1C,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100179116A1,CCOP(=O)(Cl)OCC.N#CCCCNCCCC#N>>CCOP(=O)(OCC)N(CCCC#N)CCCC#N,,ClCCl,,CCN(CC)CC,,test
US20130059834A1,CN(C)C(=O)CCn1nc(-c2cnc3c(n2)c(C(=O)NC(C)(C)C)cn3COCC[Si](C)(C)C)c2cc(OC(F)F)ccc21>>CN(C)C(=O)CCn1nc(-c2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)c2cc(OC(F)F)ccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040082611A1,CCOC(=O)c1cnc(-c2ccncc2)nn1>>O=C(O)c1cnc(-c2ccncc2)nn1,,C1CCOC1,CO,[Na+].[OH-],,test
US20090137454A1,CC(C)(C)OC(=O)[C@@H](N)CCC(=O)O.CC(C)(C)OC(=O)c1cc(OCCCCCCCCCC(=O)ON2C(=O)CCC2=O)cc(C(=O)OC(C)(C)C)c1>>CC(C)(C)OC(=O)c1cc(OCCCCCCCCCC(=O)N[C@@H](CCC(=O)O)C(=O)OC(C)(C)C)cc(C(=O)OC(C)(C)C)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20130225574A1,CCN(CC)CC.CO.ClCCl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COC[C@H]1COC(=O)N1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05534518,CCCC[Sn](CCCC)(CCCC)c1ccc(Cl)s1.Cc1c(I)ccc(N)c1C#N>>Cc1c(-c2ccc(Cl)s2)ccc(N)c1C#N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US04724237,CN1c2ccccc2C(c2ccccc2F)=NCC1CN.O=C(O)Cc1c[nH]c2ccccc12>>CN1c2ccccc2C(c2ccccc2F)=NCC1CNC(=O)Cc1c[nH]c2ccccc12.O,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20160243125A1,O=P(Cl)(Cl)Cl.O=c1[nH]cnn2cccc12>>Clc1ncnn2cccc12,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US04410534,Cc1cc2n(c1C(=O)c1cccs1)CCCC2C(=O)OC(C)C>>Cc1cc2n(c1C(=O)c1cccs1)CCCC2C(=O)O,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(F)cc23)cc1.Nc1ccc2c(c1)NC(=O)CO2>>O=C1COc2ccc(Nc3nc4ccc(F)cc4c4cn[nH]c34)cc2N1,C1COCCO1,CO,,Cl,,test
US20010038824A1,CCCCCCCOc1ccc(-c2ccc(CCC(=O)OCC)cc2)cc1>>CCCCCCCOc1ccc(-c2ccc(CCCO)cc2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06756388B1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1ccc2ncsc2c1>>O=S(=O)(Oc1ccc2ncsc2c1)C(F)(F)F,CN(C)c1ccncc1,,,CCN(CC)CC,,test
US20150011548A1,CCOC(=O)Cn1cc(-c2cnc3c(c2)ncn3-c2cc(NC(C)=O)cc(-c3ccc(F)cc3F)c2)nn1.N>>CC(=O)Nc1cc(-c2ccc(F)cc2F)cc(-n2cnc3cc(-c4cn(CC(N)=O)nn4)cnc32)c1,,CO,,,,test
US20060025592A1,COC(=O)NC(C(=O)NCCCC[C@@H](COC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1)C(c1ccccc1)c1ccccc1>>COC(=O)NC(C(=O)NCCCC[C@@H](COC(=O)[C@@H](N)C(C)C)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1)C(c1ccccc1)c1ccccc1,[Pd],C1CCOC1,,,,test
US20090312309A1,CC(C)N1CCNCC1.Clc1cnccn1>>CC(C)N1CCN(c2cnccn2)CC1,,CC(C)=O,,CCN(CC)CC,,test
US20050136357A1,CCCCOC(=O)c1ccc(I)cc1.OB(O)c1ccc(C(F)(F)F)cc1>>CCCCOC(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20090054451A1,CI.O=C(Cc1nn[nH]n1)NC1CCN(CCC(c2ccccc2)c2ccccc2)CC1>>Cn1nnnc1CC(=O)NC1CCN(CCC(c2ccccc2)c2ccccc2)CC1,,C1CCOC1,,[Na+].[OH-],,test
US06015774,CCOC(=O)C(C)Br.Cn1c(C(F)(F)F)cnc(-c2cc(N)c(Cl)cc2F)c1=O>>CCOC(=O)C(C)Nc1cc(-c2ncc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl,,O,,,,test
US04245102,COCCN1CC(c2ccccc2)NC1=S>>c1ccc([C@H]2CN3CCSC3=N2)cc1,,Cl,O,,,test
US20110212939A1,COC(=O)Cc1ccc(O)cc1.OCCCC1CCN(c2ncc(Cl)cn2)CC1>>COC(=O)Cc1ccc(OCCCC2CCN(c3ncc(Cl)cn3)CC2)cc1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20070287725A1,C#CCCCn1c(COCC)nc2c(Cl)nc3ccccc3c21.ON=C(Cl)c1ccccc1>>CCOCc1nc2c(Cl)nc3ccccc3c2n1CCCc1cc(-c2ccccc2)no1,,ClCCl,,CCN(CC)CC,,test
US20050277685A1,COC(=O)[C@@H](C)Oc1ccc(Cl)c(Cn2c(C)c(-c3noc4cc(OC)ccc34)c3ccc(OC(F)(F)F)cc32)c1>>COc1ccc2c(-c3c(C)n(Cc4cc(O[C@H](C)C(=O)O)ccc4Cl)c4cc(OC(F)(F)F)ccc34)noc2c1,,CO,,[Na+].[OH-],,test
US20120184562A1,CO.COc1cc(NCc2ccccc2)c(C(=O)O)cn1>>COC(=O)c1cnc(OC)cc1N,,O=S(=O)(O)O,,O=C([O-])O.[Na+],,test
US05338853,CC1(C)CC(N)CC(C)(C)N1.CCC(CCCC(=O)Cl)C(=O)Cl.NN>>CC1(C)CC(NC(=O)CCCCC(=O)NN)CC(C)(C)N1,,CO,,O,,test
US20060173043A1,C=CCN(Cc1ccc(OC)cc1OC)C(=O)C(=C)CCC(=O)OC>>COC(=O)CCC1=CCN(Cc2ccc(OC)cc2OC)C1=O,[Ru],ClCCl,,,,test
US20070197448A1,COC(=O)C1C2C(CN1C(=O)C(NC(=O)NC1(CS(=O)(=O)N(C)C)CCCCC1)C(C)(C)C)C2(C)C>>CN(C)S(=O)(=O)CC1(NC(=O)NC(C(=O)N2CC3C(C2C(=O)O)C3(C)C)C(C)(C)C)CCCCC1,,C1CCOC1,O,[Li+].[OH-],,test
US20020091135A1,O=Cc1ccc(Br)s1.Sc1ccc(Cl)cc1>>O=Cc1ccc(Sc2ccc(Cl)cc2)s1,,C1CCOC1,,[H-].[Na+],,test
US20110059954A1,COc1ccc2c(c1)CCN(C1CCNCC1)C(=O)N2.Cc1cc(C(=O)c2cc(F)cc(F)c2)cc2oc(=O)n(C)c12>>COc1ccc2c(c1)CCN(C1CCN(c3cc(F)cc(C(=O)c4cc(C)c5c(c4)oc(=O)n5C)c3)CC1)C(=O)N2,,CN(C)C=O,,,,test
US20150166716A1,CNC.O=C(c1ccccc1)c1ccc(OCC(CO)(CO)CBr)cc1>>CN(C)CC(CO)(CO)COc1ccc(C(=O)c2ccccc2)cc1,,CCO,,,,test
US20160244444A1,CC(=O)Nc1ncc(S(=O)(=O)N2CCCOCC2)s1>>Nc1ncc(S(=O)(=O)N2CCCOCC2)s1,,CCO,,Cl,,test
US20100130545A1,COc1ccc(OC)c([N+](=O)[O-])c1[N+](=O)[O-]>>COc1ccc(OC)c(N)c1N,,CCO,,,,test
US05037834,CC(=O)N1CCc2nc(NC(=N)N)sc2C1>>N=C(N)Nc1nc2c(s1)CNCC2,,CCO,,[Na+].[OH-],,test
US20100168082A1,CC1(C(=O)CC#N)CC1.CNN>>Cn1nc(N)cc1C1(C)CC1,,C1COCCO1,CCO,Cl,,test
US04346225,CC(C)=O.CNC(=S)NN.O=C(Cl)c1cccc(C(F)(F)F)c1>>CNC1=NN(C(=O)c2cccc(C(F)(F)F)c2)C(C)(C)S1,,c1ccncc1,,,,test
US08664217B2,CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCNCCc3cccnc3)ccc21.O=Cc1ccncc1>>CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCc3cccnc3)Cc3ccncc3)ccc21,,ClCCCl,ClCCl,CC(=O)O,[Na],test
US20120157436A1,CC(C)(C)OC(=O)N1CCn2c(nnc2C(N)=O)C1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)OC(=O)N1CCn2c(nnc2C(N)=S)C1,,c1ccccc1,,,,test
US20140364432A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1ccc(F)cn1>>CC(C)(C)OC(=O)NCc1ccc(F)cn1,,ClCCl,,,,test
US20130065877A1,CS(=O)(=O)O[C@H]1CCC(c2ccc(NC(=O)OCc3ccccc3)cc2)C1.C[C@H]1CCCN1>>C[C@H]1CCCN1C1CC[C@H](c2ccc(NC(=O)OCc3ccccc3)cc2)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04324796,CCOC(=O)C(CCCCc1ccccc1)C(=O)OCC>>CCOC(=O)C(CCCCc1ccccc1)C(=O)O,,CCO,,[K+].[OH-],,test
US06048884,NCCc1ccc(NC(=O)Cc2csc(NCc3ccccc3)n2)cc1.c1ccc(OC[C@@H]2CO2)cc1>>O=C(Cc1csc(NCc2ccccc2)n1)Nc1ccc(CCNC[C@H](O)COc2ccccc2)cc1,,CC(C)O,,,,test
US20010047031A1,O=S(=O)(c1ccc(O)cc1)C1CCN(CCCCc2cccc(OCc3ccccc3)c2)C1>>O=S(=O)(c1ccc(O)cc1)C1CCN(CCCCc2cccc(O)c2)C1,[Pd],CO,,[H][H],,test
US06410580B1,CC(C)(C)OC(=O)[C@@H](CCI)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(-c2ccc(Cl)cc2)cc1.CN1C(=O)NC(=O)C1(C)C>>CN1C(=O)N(CC[C@H](C(=O)OC(C)(C)C)N(C(=O)OC(C)(C)C)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C(=O)C1(C)C,C1COCCOCCOCCOCCOCCO1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160016947A1,COc1ccc(Cn2[nH]c(=O)cc(Br)c2=O)cc1.COc1ccc([C@H]2C[C@@H]2CO)nc1>>COc1ccc(Cn2nc(OC[C@H]3C[C@@H]3c3ccc(OC)cn3)cc(Br)c2=O)cc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140142102A1,CC(C)N1CCN(c2cc(OC(F)(F)F)cc(C3OCCO3)c2)CC1>>CC(C)N1CCN(c2cc(C=O)cc(OC(F)(F)F)c2)CC1,,O,,O=CO,,test
US20040142981A1,N#Cc1cc(Br)ccc1N.O=C(Cl)c1ccc(S(=O)(=O)N2CCc3cc(Cl)ccc32)cc1>>N#Cc1cc(Br)ccc1NC(=O)c1ccc(S(=O)(=O)N2CCc3cc(Cl)ccc32)cc1,,ClCCl,c1ccncc1,,,test
US20130172325A1,BrCc1ccccc1.CC(C)(C)OC(=O)N1CCNC(=O)CC1>>CC(C)(C)OC(=O)N1CCC(=O)N(Cc2ccccc2)CC1,,C1CCOC1,O,[H-].[Na+],,test
US20080146636A1,CC(=O)Cl.CC(C)(O)c1nc2cc(Cl)ccc2n1[C@H]1CC[C@@H](NC[C@H]2Cc3ccc(C#N)cc3C2)CC1>>CC(=O)N(C[C@H]1Cc2ccc(C#N)cc2C1)[C@@H]1CC[C@H](n2c(C(C)(C)O)nc3cc(Cl)ccc32)CC1,CN(C)c1ccncc1,ClCCl,ClCCl,CCN(CC)CC,,test
US20120258957A1,COc1cc2c(cc1OC)C(CO)NCC2.O=C(Oc1c(F)c(F)c(F)c(F)c1F)[C@@H]1Cc2ccccc2CN1Cc1ccccc1F>>COc1cc2c(cc1OC)[C@@H](CO)N(C(=O)C1Cc3ccccc3CN1Cc1ccccc1F)CC2,,CC#N,,CCN(C(C)C)C(C)C,,test
US20040092742A1,COC(c1ccccc1)(c1ccccc1)C(O)C#N.COc1cc(OC)nc(S(C)(=O)=O)n1>>COc1cc(OC)nc(OC(C#N)C(OC)(c2ccccc2)c2ccccc2)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US06350749B1,CC(=O)CCl.O=C1CC(=O)CC(c2ccccc2Br)C1>>Cc1coc2c1C(=O)CC(c1ccccc1Br)C2,,CN(C)C=O,,[H-].[Na+],,test
US20130150339A1,COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(-c4ccc(C(F)(F)F)cc4OC)nc(Cl)cc3c2)cc1>>COc1cc(C(F)(F)F)ccc1-c1nc(Cl)cc2cc(S(=O)(=O)Nc3nccs3)ccc12,,CO,,ClCCl,O=C(O)C(F)(F)F,test
US07495007B2,COC(=O)C(C)(C)COc1ccc(Br)cc1C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12>>CC(C)(CO)COc1ccc(Br)cc1C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150315198A1,OCc1cc(-c2ccc(Cl)s2)on1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>[N-]=[N+]=NCc1cc(-c2ccc(Cl)s2)on1,,C1CCOC1,CCOC(C)=O,C1CCC2=NCCCN2CC1,,test
US20150368182A1,CCN(CC)CC.CCO.O=S(=O)(F)F>>CC[N+](CC)(CC)CC.O=S(=O)([O-])F,,CC#N,,N,,test
US20150344408A1,COC(=O)Cc1ccc(O[C@H](CCN(C)C(=O)OC(C)(C)C)c2ccccc2)cc1>>CN(CC[C@@H](Oc1ccc(CCO)cc1)c1ccccc1)C(=O)OC(C)(C)C,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150065705A1,CC(C)(C)OC(=O)NC1CCN(c2ccc(F)cc2)C1.CI>>CN(C(=O)OC(C)(C)C)C1CCN(c2ccc(F)cc2)C1,,CCOC(C)=O,,CN(C)C=O,[H-].[Na+],test
US20040058978A1,CS(=O)(=O)N(CC#N)c1ccc([N+](=O)[O-])cc1>>CS(=O)(=O)N(CC#N)c1ccc(N)cc1,,CN(C)C=O,,,,test
US04851526,CN(C)C1CCCCC1O.CS(=O)(=O)OS(C)(=O)=O>>CN(C)C1CCCCC1OS(C)(=O)=O,,CC#N,,,,test
US20060160814A1,CC(C)NCCN.CCOC(=N)CC#N>>CC(C)N1CCN=C1CC#N,,ClCCl,,Cl,O=C([O-])O.[Na+],test
US05665718,CN1Cc2c(-c3noc(CN4CCCCC4)n3)ncn2-c2ccc(F)c(Cl)c2C1=O.Cl>>CN1Cc2c(-c3noc(CN4CCCCC4)n3)ncn2-c2ccc(F)c(Cl)c2C1=O.Cl,,CCO,,,,test
US20040023999A1,COc1ccc(F)cc1C(C)(C)CC(=O)C(F)(F)F.Cc1cc(C)nc(C)c1>>COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc(C)cc(C)n1)C(F)(F)F,,C1CCOC1,,[Li]C(C)(C)C,,test
US20060052600A1,COc1ccc(C(C)(C)C#N)c(Cl)c1.O=C1CCC(=O)N1Br>>COc1cc(Cl)c(C(C)(C)C#N)cc1Br,,O=C(O)C(F)(F)F,,,,test
US20140256729A1,CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1cncs1.Cl>>Cl.N[C@@H]1C[C@H]1c1cncs1,,C1COCCO1,,,,test
US04362728,CSc1nccc(N)n1.FC(F)(F)CN=C=S>>CSc1nccc(NC(=S)NCC(F)(F)F)n1,,CC#N,,,,test
US20160221998A1,C=NC(C)(C)C(=O)OCc1ccc([N+](=O)[O-])cc1.CC1=C(c2cncnc2)C(=O)OC(C)(C)O1>>CC1=C(c2cncnc2)C(=O)N(C(C)(C)C(=O)OCc2ccc([N+](=O)[O-])cc2)CO1,,Cc1ccccc1C,,,,test
US07396844B1,CC(C)(C)OC(=O)N1CCNCC1.COC(=O)c1ccc(C(=O)[O-])cc1>>COC(=O)c1ccc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cc1,,CN(C)C=O,Cl,CCN(CC)CC,,test
US20050124656A1,CCCCCCCCCCCCNS(=O)(=O)c1ccc(CN)s1.O=C1CCCC1>>CCCCCCCCCCCCNS(=O)(=O)c1ccc(CNC2CCCC2)s1,,CN(C)C=O,,[BH3-]C#N.[Na+],,test
US20150218116A1,C=CS(=O)(=O)Cc1ccc(Br)cc1.CC[C@@H](C)N>>CC[C@@H](C)NCCS(=O)(=O)Cc1ccc(Br)cc1,,ClCCl,,,,test
US20140243526A1,C=CCCCCCCCCC=O>>C=CCCCCCCCCCO,,CCCCCCC,,,,test
US20100331326A1,Brc1cnn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c1.Cc1ccncc1N1CCNC1=O>>Cc1ccncc1N1CCN(c2cnn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c2)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=C([O-])[O-].[K+].[K+],test
US20100022515A1,CS(=O)(=O)N1CCc2cc(O)ccc2C1.CS(=O)(=O)OCCCc1ccc(Br)cc1>>CS(=O)(=O)N1CCc2cc(OCCCc3ccc(Br)cc3)ccc2C1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04031221,FC(F)(F)c1ccc(OC2CCN(Cc3ccccc3)CC2)cc1>>FC(F)(F)c1ccc(OC2CCNCC2)cc1,[Pd],CCO,,[H][H],,test
US20110039847A1,NC(=S)c1ccccc1.O=C(CBr)c1ccccc1[N+](=O)[O-]>>O=[N+]([O-])c1ccccc1-c1csc(-c2ccccc2)n1,,CCO,,,,test
US20150266881A1,Cc1nnc(NC(=O)c2cccc([C@@H]3C[C@H]3N)c2)s1.Cl.O=C1CCC1>>Cc1nnc(NC(=O)c2cccc([C@@H]3C[C@H]3NC3CCC3)c2)s1.Cl,,CC(=O)O,CO,Cl,O=C([O-])O.[Na+],test
US20140128374A1,COc1ccc(CC(C)=O)c(C)c1.O=[Se]=O>>COc1ccc(C(=O)C(C)=O)c(C)c1,,C1COCCO1,,,,test
US20100292215A1,CC(C)(C)ON1CCC(O)CC1=C=O.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120088770A1,CCOC(=O)CBr.CNN>>CCOC(=O)CN(C)N,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20140349972A1,CCOP(=O)(OCC)c1cccc(CC(=O)O)c1.Nc1cnc(-c2cccnn2)nc1O>>CCOP(=O)(OCC)c1cccc(CC(=O)Nc2cnc(-c3cccnn3)nc2O)c1,,CC#N,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090023720A1,CC(C)(O)CNc1c(N)c(Cl)nc2ccccc12.N#CBr>>Br.CC(C)(O)Cn1c(N)nc2c(Cl)nc3ccccc3c21,,CCO,,,,test
US20120142717A1,COC(=O)/C(=C/O)Cc1cnc(OC)nc1.N=C(N)OCCc1ccc(Oc2cccc(C(F)(F)F)n2)c(F)c1>>COc1ncc(Cc2c[nH]c(OCCc3ccc(Oc4cccc(C(F)(F)F)n4)c(F)c3)nc2=O)cn1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20150232481A1,C=CC[C@H](C)Oc1cc(C)ccc1C=O.C[Mg]I>>C=CC[C@H](C)Oc1cc(C)ccc1C(C)O,,CCOCC,O,,,test
US20140081017A1,COC(=O)Cc1ccc(CCCCc2ccc(N)cc2)cc1.O=S(=O)(Cl)CCCl>>C=CS(=O)(=O)Nc1ccc(CCCCc2ccc(CC(=O)OC)cc2)cc1,,ClCCl,,CCN(CC)CC,,test
US20130274253A1,CC1CN(c2cc(=O)[nH]c(CC(=O)O)n2)CCO1.CCN=C=NCCCN(C)C.CN(C)C=O.c1ccncc1>>CC1CN(c2cc(=O)[nH]c(CC(=O)N3c4ccccc4C[C@@H]3C)n2)CCO1,,O,,Cl,[Na],test
US20120202777A1,CC(CCc1ccc(Sc2ccccc2)cc1)(C(=O)NOC1CCCCO1)S(C)(=O)=O>>CC(CCc1ccc(Sc2ccccc2)cc1)(C(=O)NO)S(C)(=O)=O,,ClCCl,,CO,Cl,test
US20090048264A1,Cc1cc(F)ccc1N1CCN(C(=O)OC(C)(C)C)CC1C(=O)O.Cc1ccc(C)c(N2CCNCC2)c1>>Cc1ccc(C)c(N2CCN(C(=O)C3CN(C(=O)OC(C)(C)C)CCN3c3ccc(F)cc3C)CC2)c1,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030036651A1,CCOC(=O)CCCCc1ccccn1.O=Cc1cccnc1Nc1cccc([N+](=O)[O-])c1>>O=c1c(CCCc2ccccn2)cc2cccnc2n1-c1cccc([N+](=O)[O-])c1,,CN(C)C=O,,CC(C)[N-]C(C)C.[Li+],,test
US20060052396A1,CC(C)(C)OC(=O)N1CCN(CCOc2ccc(-c3cnc(N)c(C(=O)Nc4cccnc4)n3)cc2)CC1.Cl>>Cl.Nc1ncc(-c2ccc(OCCN3CCNCC3)cc2)nc1C(=O)Nc1cccnc1,,CO,,,,test
US20160031840A1,COc1ccccc1CCC1CCNCC1.Fc1ccc(CCBr)cc1>>COc1ccccc1CCC1CCN(CCc2ccc(F)cc2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05763450,C#Cc1ccc2ccccc2c1.COc1cc(Cc2cnc(N)nc2N)cc(I)c1OC>>COc1cc(Cc2cnc(N)nc2N)cc(C#Cc2ccc3ccccc3c2)c1OC,[Cu]I,CN(C)C=O,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,O=C([O-])[O-].[K+].[K+],test
US20100093733A1,CC(=O)OC(C)=O.CC(C)OC(=O)[C@@H]1CC[C@@H](c2ccc(N)cc2)CC1>>CC(=O)Nc1ccc([C@@H]2CC[C@@H](C(=O)OC(C)C)CC2)cc1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20090029962A1,CC(C)(C)OC(=O)N1CC[C@H]1C=O.Nc1ccc(Cl)cc1>>CC(C)(C)OC(=O)N1CC[C@H]1CNc1ccc(Cl)cc1,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US04058611,O=c1cc(-c2cnccn2)ss1.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>S=c1cc(-c2cnccn2)ss1,,C1COCCO1,CC#N,,,test
US04442109,C=O.CS(=O)[O-].Cc1ccc2c(O)ccnc2c1>>Cc1ccc2c(O)c(CS(C)(=O)=O)cnc2c1,,O,,CCN(CC)CC,,test
US20060063805A1,NC1CC1c1ccc(F)cc1.O=C1CSC(=S)N1>>O=C1CSC(NC2CC2c2ccc(F)cc2)=N1,Cl[Hg]Cl,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20120245144A1,CC(C)(O)C1CCNCC1.Cc1cn(C(C)C)c(-c2cn3c(n2)-c2cc(C(C)OS(C)(=O)=O)ccc2OCC3)n1>>Cc1cn(C(C)C)c(-c2cn3c(n2)-c2cc(C(C)N4CCC(C(C)(C)O)CC4)ccc2OCC3)n1,,C1COCCO1,,,,test
US20050288317A1,O=C(O)[C@@H]1CCCN(S(=O)(=O)c2ccccc2[N+](=O)[O-])C1.c1cncc(C2CCNC2)c1>>O=C([C@@H]1CCCN(S(=O)(=O)c2ccccc2[N+](=O)[O-])C1)N1CCC(c2cccnc2)C1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20120271046A1,CC(C)(Br)C(=O)NOCc1ccccc1>>C=C(C)C(=O)NOCc1ccccc1,,CCOCC,,,,test
US20090075869A1,C=CCCCS(=O)(=O)Cl.C=Cc1ccc2nc(-c3ccccc3)cc(O[C@@H]3C[C@@H](C(=O)OC)N(C(=O)[C@H](CCCC)NC(=O)OC(C)(C)C)C3)c2c1>>C=CCCCS(=O)(=O)N[C@@H](CCCC)C(=O)N1C[C@H](Oc2cc(-c3ccccc3)nc3ccc(C=C)cc23)C[C@H]1C(=O)OC,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,Cl,test
US20080045550A1,CC(C)(C)OC(=O)N1CCC(N)CC1.Clc1cc(Cl)nc(Cl)n1>>CC(C)(C)OC(=O)N1CCC(Nc2cc(Cl)nc(Cl)n2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US05994378,CC(C)(C)c1csc(-c2cc3cc(O)ccc3o2)n1.CCOC(=O)C(C)Oc1c(CO)cccc1OC>>CCOC(=O)C(C)Oc1c(COc2ccc3oc(-c4nc(C(C)(C)C)cs4)cc3c2)cccc1OC,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04968710,CC(C)(C)c1cc(S)cc(C(C)(C)C)c1O.N#Cc1ccc(CBr)cc1>>CC(C)(C)c1cc(SCc2ccc(C#N)cc2)cc(C(C)(C)C)c1O,,O,,CCO,[Na+].[OH-],test
US03997535,CN.O=C(Nc1nnn[nH]1)c1nc2ccccc2nc1Cl>>CNc1nc2ccccc2nc1C(=O)Nc1nnn[nH]1,,CCO,,,,test
US20030100554A1,CCc1n[nH]c(CCOCc2ccccc2)c1Oc1cc(F)cc(C#N)c1>>CCc1n[nH]c(CCO)c1Oc1cc(F)cc(C#N)c1,Cl[Fe](Cl)Cl,ClCCl,,,,test
US20100105655A1,COc1cc(OC2CCNCC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1.CS(=O)(=O)Cl>>COc1cc(OC2CCN(S(C)(=O)=O)CC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1,,ClCCl,,CCN(CC)CC,,test
US20140221343A1,CC(C)(C)c1ccc(O)c(O)c1.ICI>>CC(C)(C)c1ccc2c(c1)OCO2,,CS(C)=O,,[Na+].[OH-],,test
US20140343092A1,COC(=O)C(OC(C)(C)C)c1c(-c2ccc(C)cc2)c2ccn(Cc3ccc4nonc4c3)c2c(=O)n1C>>Cc1ccc(-c2c(C(OC(C)(C)C)C(=O)O)n(C)c(=O)c3c2ccn3Cc2ccc3nonc3c2)cc1,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20080085890A1,CN(C)/C=C1/C(=O)NCc2ccccc21.Nc1ccc(CN2CCCCC2)cc1>>O=C1NCc2ccccc2C1=CNc1ccc(CN2CCCCC2)cc1,,CN(C)C=O,,,,test
US20030004181A1,CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)N)cc1)n2C)c1ccccn1.O=C(Cl)OCc1ccccc1>>CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)NC(=O)OCc3ccccc3)cc1)n2C)c1ccccn1,,CO,ClCCl,Cl,,test
US05360814,CCOC(=O)C(CBr)=NO.Clc1cc(Cl)c2cc[nH]c2c1>>N[C@@H](Cc1c[nH]c2cc(Cl)cc(Cl)c12)C(=O)O,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20080090818A1,CC(C)N1CCN(c2ccc(Nc3ncc(Br)n4ncnc34)cn2)CC1.CC1(C)OB(c2csc(C(N)=O)c2)OC1(C)C.CN1CCN(c2ccc(Nc3ncc(-c4csc(C(N)=O)c4)n4ncnc34)cc2)CC1>>CC(C)N1CCN(c2ccc(Nc3ncc(-c4csc(C(N)=O)c4)n4ncnc34)cc2)CC1.N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20160039834A1,CN(CC(COc1cccc(-c2nc(-c3cn(S(C)(=O)=O)c4ncncc34)cc(N(C)C3CCOCC3)n2)c1)O[Si](C)(C)C(C)(C)C)C(=O)OC(C)(C)C>>CNCC(O)COc1cccc(-c2nc(-c3cn(S(C)(=O)=O)c4ncncc34)cc(N(C)C3CCOCC3)n2)c1.O=CO,,C1COCCO1,Cl,,,test
US20100297079A1,CC(=O)O[C@@H]1[C@@H]2O[Si](C(C)C)(C(C)C)O[Si](C(C)C)(C(C)C)OC[C@H]2O[C@H]1n1cc(C(=N)N)c2c(N)ncnc21>>CC(C)[Si]1(C(C)C)OC[C@H]2O[C@@H](n3cc(C(=N)N)c4c(N)ncnc43)[C@H](O)[C@@H]2O[Si](C(C)C)(C(C)C)O1,,CO,N,,,test
US04302607,CI.O=C1C=CCCCCCCCCCCC=C1>>CC1CCCCCCCCCCC=CC(=O)C1,,CCOCC,,[Mg],[Cl-].[NH4+],test
US20050005370A1,COCc1ccc([N+](=O)[O-])c(O)c1>>COCc1ccc(N)c(O)c1,O=[Pt]=O,CCO,,[H][H],,test
US04962103,CC(O)=S.COc1ccc(COC(=O)C[C@@H]2C[C@@H](O)CN2C(=O)OCc2ccc([N+](=O)[O-])cc2)cc1>>COc1ccc(COC(=O)C[C@@H]2C[C@H](SC(C)=O)CN2C(=O)OCc2ccc([N+](=O)[O-])cc2)cc1,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080269244A1,CC(C)(C)OC(=O)N1CCN(c2ccc(N)cn2)CC1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)nc2)cc1,,CS(C)=O,O,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20020132796A1,COC(=O)Cc1ccc(C#Cc2ccc(C3(OC(C)C)CC3)c(C)c2)cc1>>Cc1cc(C#Cc2ccc(CC(=O)O)cc2)ccc1C1(OC(C)C)CC1,,C1CCOC1,CCO,[Na+].[OH-],,test
US04203980,C=C(C)c1c(OC)cc(Cc2cnc(N)nc2N)cc1OC.Cl>>C=C(C)c1c(OC)cc(Cc2cnc(N)nc2N)cc1OC.Cl,,CO,,,,test
US20020052376A1,COC(=O)c1cc(O)ccc1CCc1ccc(F)cc1.Cn1cncc1CC(O)c1nccs1>>COC(=O)c1cc(OC(Cc2cncn2C)c2nccs2)ccc1CCc1ccc(F)cc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05177089,O=Cc1cccc(Br)c1.c1c[nH]cn1>>O=Cc1cccc(-n2ccnc2)c1,[Cu],O,,N,,test
US20040235905A1,CC(=O)O.CC(=O)OO.CC(=O)c1cc(OCc2ccccc2)ccc1OCc1ccccc1>>CC(=O)Oc1cc(OCc2ccccc2)ccc1OCc1ccccc1,,CC(=O)O,,,,test
US20040053826A1,Cc1ccc(B(O)O)cc1.Nc1c2c(nc3ccc(Br)cc13)N(Cc1ccccc1)CC2>>Cc1ccc(-c2ccc3nc4c(c(N)c3c2)CCN4Cc2ccccc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US04983607,COC(=O)CC1CC(=O)Nc2ccccc21>>O=C1CC(CCO)c2ccccc2N1,,C1COCCO1,CCOCC,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20150291573A1,CS(=O)(=O)OC1CCOC(c2cc(Br)ccc2Br)C1.FC(F)(F)c1cccc(S)c1>>FC(F)(F)c1cccc(SC2CCOC(c3cc(Br)ccc3Br)C2)c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20060100425A1,CN1C(=O)c2ccccc2C1=O>>CN1C(=O)c2ccccc2C1O,,CO,,[BH4-].[Na+],,test
US04788206,COc1cccc(C(=CC=Cc2ccccc2)C(=O)O)c1.NCCCCc1cccnc1>>COc1ccccc1/C(=C/C=C/C(=O)NCCCCc1cccnc1)c1ccccc1,,C1CCOC1,,,,test
US20120058984A1,CCOC(OCC)c1cc(Nc2nc3ccc(Br)cc3s2)nc(N[C@@H]2CC[C@@H](O)CC2)n1>>O=Cc1cc(Nc2nc3ccc(Br)cc3s2)nc(N[C@@H]2CC[C@@H](O)CC2)n1,,C1CCOC1,,Cl,,test
US20030100576A1,CC(=O)OCCBr.CNc1ccccc1>>CCOC(=O)CN(C)c1ccccc1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US05475106,COc1cccc(N(CC(=O)OC(C)(C)C)C(=O)CCl)c1.O=C1NC(=O)c2ccccc21>>COc1cccc(N(CC(=O)OC(C)(C)C)C(=O)CN2C(=O)c3ccccc3C2=O)c1,,CN(C)C=O,,O,[K],test
US04880784,Nc1ncn([C@@H]2O[C@H](COC(=O)c3ccccc3)[C@@H](OC(=O)c3ccccc3)[C@H]2OC(=O)c2ccccc2)c2nc(=O)sc1-2>>Nc1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2nc(=O)sc1-2,,CO,,C[O-].[Na+],,test
US04436748,COc1cc2cc(-c3ccccc3)sc2c(Cl)c1Cl>>Oc1cc2cc(-c3ccccc3)sc2c(Cl)c1Cl,,Cl,,c1ccncc1,,test
US20160159773A1,COc1ccc(COC(C)(C)c2cc(N3C(=O)c4ccccc4C3=O)n[nH]2)cc1.FC(F)Cl>>COc1ccc(COC(C)(C)c2cc(N3C(=O)c4ccccc4C3=O)nn2C(F)F)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04857517,CCOCC.C[Mg]Br.O=C1CC=Cc2ccccc2O1>>CC(C)(O)CCCc1ccccc1O,,O,,Cl,,test
US06022884,CNc1ccc(Oc2ccc(Cl)cc2C)nc1.O=C(Cl)c1c(Cl)cccc1Cl>>Cc1cc(Cl)ccc1Oc1ccc(N(C)C(=O)c2c(Cl)cccc2Cl)cn1,,ClCCl,,CCN(CC)CC,,test
US20020193269A1,CCCCCCC(O)CCC(=O)OCCC(C)CCC=C(C)C.O=C(Cl)OCCc1ccccc1>>CCCCCCC(CCC(=O)OCCC(C)CCC=C(C)C)OC(=O)OCCc1ccccc1,,C1CCOC1,,O,c1ccncc1,test
US20160185785A1,COC(=O)C(=CN(C)C)c1ccc(C(=O)OC)cc1.NN>>COC(=O)c1ccc(-c2c[nH][nH]c2=O)cc1,,CCO,,CCN(CC)CC,Cl,test
US05856529,O=C(O)c1cccc2c1CCO2>>OCc1cccc2c1CCO2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150150868A1,O=C(O)c1ccccc1O.O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1>>O=C(O)c1ccccc1O.O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1,,CS(C)=O,,CO,,test
US20070197478A1,NCc1ccccc1.O=[N+]([O-])c1c(Cl)cc(C2CC2)nc1Cl>>O=[N+]([O-])c1c(NCc2ccccc2)cc(C2CC2)nc1Cl,,C1CCOC1,,CCN(CC)CC,,test
US20100075953A1,CC(C)(C)OC(=O)N1CCNCC1.O=C(Cl)Cl.c1cc(N2CCNCC2)ccc1OCCCN1CCCCC1>>CC(C)(C)OC(=O)N1CCN(C(=O)N2CCN(c3ccc(OCCCN4CCCCC4)cc3)CC2)CC1,,Cc1ccccc1,ClCCl,CCN(CC)CC,,test
US20120190701A1,CS(=O)(=O)Cl.Cc1ncccc1CO>>Cc1ncccc1COS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20040132994A1,CC(C)(C)OC(=O)NCCC(=O)Nc1cnn(CCF)c1N.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)NCCC(=O)Nc1cnn(CCF)c1NC(c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)c1ccncc1,CN(C)C=O,,CCN(CC)CC,O,test
US20050239827A1,O=C(O)c1cccnc1Cl.OCc1ccccc1>>O=C(O)c1cccnc1OCc1ccccc1,,C1CCOC1,O,Cl,[H-].[Na+],test
US20110201635A1,CC(C)(C/C=C1\C(=O)N(C(=O)OC(C)(C)C)c2cc(Cl)ccc21)CO[Si](C)(C)C(C)(C)C.C[Si](C)(C)C/N=C/c1cccc(Cl)c1F>>CC(C)(CO)CC1CNC(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12,,CN(C)P(=O)(N(C)C)N(C)C,,CC(=O)O,O,test
US20150094306A1,COC(=O)c1cnc(F)c(C)c1.Clc1cn[nH]c1>>COC(=O)c1cnc(-n2cc(Cl)cn2)c(C)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050176689A1,COC(=O)Cc1ccc(C#Cc2cc(OC)c3c(c2)C(C)(C)CCC3N(C)C2CC2)cc1>>COc1cc(C#Cc2ccc(CC(=O)O)cc2)cc2c1C(N(C)C1CC1)CCC2(C)C,,C1CCOC1,CO,[Li+].[OH-],,test
US20090299072A1,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)c(OCC2CC2)c([N+](=O)[O-])c1>>CCOC(=O)C(CC(C)C)c1cc(N)c(OCC2CC2)c(-c2ccc(C(F)(F)F)cc2)c1,[Fe],Cc1ccccc1,O,O=C[O-].[NH4+],,test
US20080039440A1,CNc1cc(Oc2ccc3ncccc3c2)ncn1>>CNc1cc(Oc2ccc3c(c2)CCCN3)ncn1,O=[Pt]=O,C1CCOC1,CC(=O)O,,,test
US20150210720A1,CS(=O)(=O)Cl.O=[N+]([O-])c1ccc2nn(CCO)cc2c1>>CS(=O)(=O)OCCn1cc2cc([N+](=O)[O-])ccc2n1,,ClCCl,,CCN(CC)CC,,test
US20090275550A1,CC(C)(C)S(=O)N[C@H](CCO)c1ccc(OCC(F)(F)F)cn1>>N[C@H](CCO)c1ccc(OCC(F)(F)F)cn1,,CO,,CCOCC,Cl,test
US20130131043A1,CC1CCCC1O.CS(=O)(=O)Cl>>CC1CCCC1OS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20110028512A1,COc1ccc(C2(O)c3cncn3CCC2(C)C)cc1>>COc1ccc(C2c3cncn3CCC2(C)C)cc1,[Pd],CCO,,O=S(=O)(O)O,,test
US20100267697A1,O=S(=O)(Cl)Cl.OCc1cccc(Br)n1>>ClCc1cccc(Br)n1,,ClC(Cl)Cl,,,,test
US04595690,COC(=O)Cc1ccc(S(=O)(=O)CC2COC(C)(C)O2)cc1.O>>CC1(C)OCC(COc2ccc(CCO)cc2)O1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20130059834A1,NCc1ccc(Cl)cn1.O=CO>>O=CNCc1ccc(Cl)cn1,,O,,Cl,[NH4+].[OH-],test
US03994898,CN.O=c1[nH]nc2ccc(Cl)nn12>>CNc1ccc2n[nH]c(=O)n2n1,,c1ccccc1,,,,test
US20150087585A1,BrCCBr.N#CCn1cccn1>>N#CC1(n2cccn2)CC1,,CS(C)=O,,[H-].[Na+],[Cl-].[NH4+],test
US20040006081A1,CCN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)C1CCN(Cc2ccccc2)CC1>>CCN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)C1CCNCC1,,CCO,,O=C[O-].[NH4+],,test
US04341792,O=C(CCl)NC(O)C(=O)O.c1ccc2c(c1)CCS2>>O=C(CCl)NC(C(=O)O)c1ccc2c(c1)CCS2,,O,,CC(=O)O,O=S(=O)(O)O,test
US20070208018A1,Brc1c[nH]cn1.COC(=O)c1cc(F)c(C(F)(F)F)cc1[N+](=O)[O-]>>COC(=O)c1cc(-n2cnc(Br)c2)c(C(F)(F)F)cc1[N+](=O)[O-],,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20060228387A1,CC1=CNC(=O)C2C(C)CCC12.CCCCCCI>>CCCCCCN1C[C@@H](C)[C@H]2CC[C@H](C)[C@H]2C1=O,,C1CCOC1,,,,test
US04517002,O=P(Cl)(Cl)Cl.OCC(F)(F)F>>O=P(Cl)(Cl)OCC(F)(F)F,,Cc1ccccc1,,c1ccncc1,,test
US20020013460A1,CCN1CCNCC1.Clc1cc2ccccc2c(Cl)n1>>CCN1CCN(c2nc(Cl)cc3ccccc23)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100305145A1,COC(=O)C/C=C/c1ccc2nc(C)sc2c1>>COC(=O)CCCc1ccc2nc(C)sc2c1,[Pd],C1CCOC1,,,,test
US20060079536A1,CI.Cc1ccc(CS(=O)(=O)c2cnn3c2N(Cc2ccccc2)C(c2ccccc2)CC3(C)C)cc1>>Cc1ccc(C(C)S(=O)(=O)c2cnn3c2N(Cc2ccccc2)C(c2ccccc2)CC3(C)C)cc1,,C1CCOC1,,[Li]CCCC,,test
US20090186879A1,Nc1cccc(N)c1NCCCCCO.S=C=Nc1ccc(Cl)cc1Cl>>Nc1cccc(NC(=S)Nc2ccc(Cl)cc2Cl)c1NCCCCCO,,C1CCOC1,,,,test
US20090156607A1,O=C1CC(C=C(F)F)CN1.OCc1c(C2CC2)nc2ccc(Cl)nn12>>O=C1CC(C=C(F)F)CN1Cc1c(C2CC2)nc2ccc(Cl)nn12,,Cc1ccccc1,,,,test
US20120316151A1,O=C(C[C@@H]1CCN(C(=O)C2CC2)C1)NNC(=O)Nc1ccc(Br)cc1C(F)(F)F>>O=C(C1CC1)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(Br)cc2C(F)(F)F)C1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20140323470A1,CC(C)(C)OC(=O)CCN1CCC[C@H]1c1nnc2ccc(F)cn12>>OCCCN1CCC[C@H]1c1nnc2ccc(F)cn12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100298288A1,C=C(C)c1cc(C#N)cc([N+](=O)[O-])c1O>>CC(C)c1cc(C#N)cc(N)c1O,[Pd],CCOC(C)=O,,,,test
US20070066647A1,Br[Mg]c1ccc(OC2CCCCO2)cc1.O=Cc1cc(F)cc(F)c1>>OC(c1ccc(OC2CCCCO2)cc1)c1cc(F)cc(F)c1,,C1CCOC1,,,,test
US20160159774A1,C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CNC4)ncc2F)C1.Cc1ccc(S(=O)(=O)OCC2COC2)cc1>>C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(CC3COC3)C4)ncc2F)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20160152604A1,CCC(C)n1cc(C)c2c(C(=O)NCc3c(OC)nn(C)c3C)cc(-c3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)nc3)cc21>>CCC(C)n1cc(C)c2c(C(=O)NCc3c(C)n(C)[nH]c3=O)cc(-c3ccc(N4CCNCC4)nc3)cc21,,ClCCl,,,,test
US20080255124A1,Cc1ccc(O)nc1.N#Cc1ccc(N(CCO)CC(F)(F)F)cc1C(F)(F)F>>Cc1ccc(OCCN(CC(F)(F)F)c2ccc(C#N)c(C(F)(F)F)c2)nc1,,COCCOC,,,,test
US20160068489A1,Cc1nc(N)c(C)c(C)c1OCc1ccccc1.O=C(Cl)Cc1ccccc1>>Cc1nc(NC(=O)Cc2ccccc2)c(C)c(C)c1OCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US04525356,CCN(CC)CCN.Cc1c(-c2cccc(Cl)c2)oc2c(C(=O)Cl)cccc2c1=O>>CCN(CC)CCNC(=O)c1cccc2c(=O)c(C)c(-c3cccc(Cl)c3)oc12,,c1ccccc1,,Cl,,test
US20120177681A1,CCOC(=O)N(Cc1ccc(CP(=O)(OCC)OCC)cc1)c1cc(OCCOC)nc(N)c1N>>CCOP(=O)(Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(OCCOC)cc32)cc1)OCC,,CC(=O)O,,,,test
US20130225552A1,CC(C)(C)OC(=O)N[C@@H]1C[C@@H](N2C(=O)C(F)(F)c3cc(Br)cnc32)C1>>Br.N[C@H]1C[C@H](N2C(=O)C(F)(F)c3cccnc32)C1,[Pd],CCO,,,,test
US20150266874A1,CC(=O)OCC(C)(C)C(=O)Nc1c[nH]nc1-c1nc2ccccc2[nH]1>>CC(C)(CO)C(=O)Nc1c[nH]nc1-c1nc2ccccc2[nH]1,,CCOC(C)=O,CO,O=C([O-])[O-].[K+].[K+],,test
US20100056516A1,CCOC(=O)CC(=O)N(OCc1ccccc1)c1nccc(-c2cccc(Br)c2)c1C(=O)OC>>CCOC(=O)c1c(O)c2c(-c3cccc(Br)c3)ccnc2n(OCc2ccccc2)c1=O,,CCO,,CC(C)(C)[O-].[K+],,test
US20050267093A1,CN(C)C(OC(C)(C)C)N(C)C.Cc1ccc([N+](=O)[O-])cc1Cl>>CN(C)/C=C/c1ccc([N+](=O)[O-])cc1Cl,,C1CCOC1,,,,test
US05180418,Nc1cc(SC2(C(=O)O)CC2)c(Cl)cc1F.O=C1OC(=O)C2=C1CCCC2>>O=C1C2=CCCCC2C(=O)N1c1cc(SC2(C(=O)O)CC2)c(Cl)cc1F,,CC(=O)O,,,,test
US20100331366A1,CCOC(=O)c1cccc(O)c1.OCC1CCCCC1>>CCOC(=O)c1cccc(OCC2CCCCC2)c1,,C1CCOC1,O,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20040266789A1,CC(C)(C)OC(=O)NC(Cc1ccc(I)cc1)C(=O)O.CI>>COC(=O)C(Cc1ccc(I)cc1)NC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150105394A1,ClCCc1c(Cl)ncnc1-c1ccccc1.NN>>c1ccc(-c2ncnc3c2CCNN3)cc1,,C1CCOC1,,,,test
US20110245224A1,C[C@H]1CN(c2c(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)cc(C(=O)C(F)(F)F)c(F)c2F)C[C@@H](C)O1.NO>>C[C@H]1CN(c2c(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)cc(C(=NO)C(F)(F)F)c(F)c2F)C[C@@H](C)O1,,CCO,,Cl,c1ccncc1,test
US20080312231A1,CNCCC#N.COc1cc(C)c(S(=O)(=O)Cl)c(C)c1C>>COc1cc(C)c(S(=O)(=O)N(C)CCC#N)c(C)c1C,,C1CCOC1,,CCN(CC)CC,CCOC(C)=O,test
US20080292548A1,COC(=O)c1ccc([N+](C)(C)C)c(F)c1.O=S(=O)([O-])C(F)(F)F>>C[N+](C)(C)c1ccc(C(=O)O)cc1F.O=S(=O)([O-])C(F)(F)F,,O,,O=C(O)C(F)(F)F,,test
US20020107251A1,CCC(=O)OC(=O)CC.Nc1cccc(-n2c(=O)c(Cc3ccccc3)nc3cccnc32)c1>>CCC(=O)Nc1cccc(-n2c(=O)c(Cc3ccccc3)nc3cccnc32)c1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,c1ccncc1,O=C([O-])O.[Na+],test
US20070173498A1,COC(=O)CC1=Cc2ccc(NC(C)=O)cc2CC1>>CC(=O)Nc1ccc2c(c1)CCC(CCO)=C2,,CCOC(C)=O,,C1CCOC1,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US06972297B2,CN.O=C(O)c1ccc(Cl)nn1>>CNC1(C(=O)O)C=CC=NN1,,CCO,,Cl,,test
US04997847,O=C(O)CCCC#CCN1C(=O)c2ccccc2C1=O>>NCC#CCCCC(=O)O,,CCO,,NN,O,test
US20020193367A1,COCCN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3ccnn3)c2)cc1Cl>>COCCN(C)c1cc2c(cc1Cl)NC(=O)CC(c1cccc(-n3ccnn3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050227990A1,Cc1ccccc1-c1ccc(O)c(C=O)c1.OCCCO>>Cc1ccccc1-c1ccc(O)c(C2OCCCO2)c1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080058320A1,COCCCI.COc1c(O)cc(I)nc1I>>COCCCOc1cc(I)nc(I)c1OC,,CCOC(C)=O,CN(C)C=O,O,[Na+].[OH-],test
US20140364432A1,C=CCOC(=O)N1CCC[C@@H](C)[C@H]1CN.Clc1ccc2oc(Cl)nc2c1>>C=CCOC(=O)N1CCC[C@@H](C)[C@H]1CNc1nc2cc(Cl)ccc2o1,,CC#N,,CCN(C(C)C)C(C)C,,test
US04510141,CNC.COC(=O)c1nc2n(n1)-c1ccccc1N(c1ccccc1)C2>>CN(C)C(=O)c1nc2n(n1)-c1ccccc1N(c1ccccc1)C2,,CO,,,,test
US06265421B1,CCOC(=O)C(Cc1cccc2ccccc12)C(C)=O.Oc1cc(O)cc(O)c1>>Cc1c(Cc2cccc3ccccc23)c(=O)oc2cc(O)cc(O)c12,,CCO,,Cl,,test
US20080318975A1,CNC.COC(=O)Cc1c(Cl)ccc2cnc(CBr)cc12>>COC(=O)Cc1c(Cl)ccc2cnc(CN(C)C)cc12,,C1CCOC1,,,,test
US20060058295A1,CCOC(=O)C=CC(OC)OC.Nc1ccc(Br)cn1>>CCOC(=O)Cc1cnc2ccc(Br)cn12,Cc1ccc(S(=O)(=O)O)cc1,O,,CC#N,,test
US20110172431A1,CC(C)(C)OC(=O)NC1CCN(Cc2ccccc2)CC1O>>CC(C)(C)OC(=O)NC1CCNCC1O,[Pd],CCO,,[H][H],,test
US20080039444A1,COC(=O)CCCCc1ccc(OCCCN2CCCCCC2)cc1>>OCCCCCc1ccc(OCCCN2CCCCCC2)cc1,,C1CCOC1,CCOCC,[H-].[Na+],,test
US20140221374A1,CC1(C)OB(c2cccc(N)c2)OC1(C)C.CS(=O)(=O)c1cccc(N)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC1(C)OB(c2cccc(NC(=O)Nc3cccc(S(C)(=O)=O)c3)c2)OC1(C)C,,CO,ClCCl,CCN(C(C)C)C(C)C,,test
US20160122344A1,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(O)cc1CC2C(C)(C)COC.OCCCI>>CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCCCO)cc1CC2C(C)(C)COC,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110230458A1,CCCCc1nnc(OC[C@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2O)cc1-c1ccc(OC2CCCCC2)cc1.CI>>CCCCc1nnc(OC[C@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2OC)cc1-c1ccc(OC2CCCCC2)cc1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20160214971A1,Cc1cc(C(=O)NS(C)(=O)=O)ccc1-c1cnc(F)c(Cl)c1.Cc1cc(Cl)cc(Cl)c1O>>Cc1cc(C(=O)NS(C)(=O)=O)ccc1-c1cnc(Oc2c(C)cc(Cl)cc2Cl)c(Cl)c1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080171789A1,CC(=O)OC[C@@H](C)OC(=O)[C@H](Cc1ccc(O)c(O)c1)NC(=O)OC(C)(C)C.CCOC(=O)Cl.CCOC(C)=O>>CCOC(=O)Oc1ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)O[C@H](C)COC(C)=O)cc1OC(=O)OCC,,CCCCCC,ClCCl,CCN(CC)CC,,test
US04748186,Cc1nc(N)oc1C.FC(F)=C(F)CCBr.S=C=S>>Cc1nc(NC(=S)SCCC(F)=C(F)F)oc1C,,CS(C)=O,,CCN(CC)CC,,test
US20070225292A1,COC(=O)c1nccnc1N.Cc1ccc(C(=O)Cl)c2ccccc12>>COC(=O)c1nccnc1NC(=O)c1ccc(C)c2ccccc12,CN(C)c1ccncc1,c1ccncc1,,,,test
US20040077721A1,CCOC(=O)c1cc(C#N)c2c(c1)C(C)(C)CC(C)(C)O2>>CC1(C)CC(C)(C)c2cc(C(=O)O)cc(C#N)c2O1,,CCO,,Cl,[Na+].[OH-],test
US04247551,COC1CCC(OC)O1.NNc1ccc(N2CCOCC2)nn1>>c1ccn(Nc2ccc(N3CCOCC3)nn2)c1,,CCO,CCOCC,Cl,,test
US20050288305A1,COC(=O)c1c(F)cccc1-c1cnc(C#N)nc1.Cl>>COC(=O)c1c(F)cccc1-c1cnc(CN)nc1.Cl,[Pd],CO,,[H][H],,test
US20100317568A1,CC(C)(C)OC(=O)N1CCC[C@H]1c1nc(-c2ccc(C3CCC(c4ccc([N+](=O)[O-])cc4)N3c3ccc(F)cc3)cc2)c[nH]1>>CC(C)(C)OC(=O)N1CCC[C@H]1c1nc(-c2ccc(C3CCC(c4ccc(N)cc4)N3c3ccc(F)cc3)cc2)c[nH]1,O=[Pt]=O,C1CCOC1,CCO,[H][H],,test
US20040058964A1,CCOC(=O)COc1cc(F)ccc1C.O=C1CCC(=O)N1Br>>CCOC(=O)COc1cc(F)ccc1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20100222352A1,CC(C)=CCBr.Cc1ccc(Nc2nccc(OCN)n2)cc1O>>COc1ccnc(Nc2ccc(C)c(OCC=C(C)C)c2)n1,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160168139A1,CC(=O)OC(C)=O.Nc1ccc(CCN2CCC(Nc3ccc4c(c3)Cc3cccc(-c5cc(N6CCOCC6)cc(=O)[nH]5)c3O4)CC2)cc1>>CC(=O)Nc1ccc(CCN2CCC(Nc3ccc4c(c3)Cc3cccc(-c5cc(N6CCOCC6)cc(=O)[nH]5)c3O4)CC2)cc1,,CO,,Cl,O=C([O-])O.[Na+],test
US20150299121A1,Cc1ccc(C(=O)Nc2cc(F)cc(CN3CCN[C@@H](C)C3)c2C)cn1.O=C(O)CC1CC1>>Cc1ccc(C(=O)Nc2cc(F)cc(CN3CCN(C(=O)CC4CC4)[C@@H](C)C3)c2C)cn1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090023725A1,Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(F)c(C=O)c1.NNc1ccc(Br)cc1>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc2c(cnn2-c2ccc(Br)cc2)c1,,CC#N,,,,test
US05041455,CI.Clc1nonc1-c1cccnc1>>C[n+]1cccc(-c2nonc2Cl)c1.[I-],,CC(C)=O,,,,test
US20060040965A1,COc1ccc(CN)c(OC)c1.N#CCC#N.O=C(c1ccccc1)C(O)c1ccccc1>>COc1ccc(Cn2c(N)c(C#N)c(-c3ccccc3)c2-c2ccccc2)c(OC)c1,,CCOC(C)=O,Cc1ccccc1,,,test
US20110224190A1,CCN(C)Cc1cc(C(=O)O)nc(C(F)(F)F)n1.C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C4(CC#N)CN(C5CCNCC5)C4)c3)ncnc21>>CCN(C)Cc1cc(C(=O)N2CCC(N3CC(CC#N)(n4cc(-c5ncnc6[nH]ccc56)cn4)C3)CC2)nc(C(F)(F)F)n1,,C1CCOC1,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US08026257B2,C[Mg]Br.C[Si](C)(C)CCOCn1cc2cc(C(F)(F)F)cc(C=O)c2n1>>CC(O)c1cc(C(F)(F)F)cc2cn(COCC[Si](C)(C)C)nc12,,C1CCOC1,,,,test
US20090186869A1,CCOC(=O)Cl.COc1cccc(C=CC(=O)O)c1.[N-]=[N+]=[N-]>>COc1ccc2c(Cl)nccc2c1,,C1CCOC1,O,CCN(CC)CC,,test
US20100234219A1,COC(=O)c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2ccccc12>>O=C(O)c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2ccccc12,,C1CCOC1,O,CO,[Li+].[OH-],test
US20120270857A1,COC(=O)c1cccc2ccn(CC(OC)OC)c12>>COC(=O)c1cccc2ccn(CC=O)c12,,C1CCOC1,,Cl,,test
US20050250792A1,CC(C)(C)OC(=O)NCCN.CI>>CNCCNC(=O)OC(C)(C)C,,C1CCOC1,,CCN(CC)CC,,test
US20100111862A1,C[C@H](Oc1ccccc1C(=O)O)C(F)(F)F.c1cc2c(cc1C1CCOCC1)CNC2>>C[C@H](Oc1ccccc1C(=O)N1Cc2ccc(C3CCOCC3)cc2C1)C(F)(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US05690909,FC(F)(F)C1CO1.O=C(O)CN1CCNCCN(CC(=O)O)CCN(CC(=O)O)CC1>>O=C(O)CN1CCN(CC(=O)O)CCN(CC(O)C(F)(F)F)CCN(CC(=O)O)CC1,,C1COCCO1,O,[K+].[OH-],,test
US20060063814A1,COC(=O)c1csc(NC(=O)[C@H](Cc2cn(C(=O)OC(C)(C)C)c3ccccc23)N2C(=O)NC(c3ccc4c(c3)OCCO4)C2=O)n1>>COC(=O)c1csc(NC(=O)[C@H](Cc2c[nH]c3ccccc23)N2C(=O)NC(c3ccc4c(c3)OCCO4)C2=O)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05821239,CCN(CC)C(OC)OC.Nc1ccncc1O>>CCN(C=Nc1ccncc1O)CC,,Cc1ccccc1,,,,test
US05308848,CCO.Cn1c(N2CCNCC2)cc(=O)n(C)c1=O.O=C(O)C(CBr)c1ccccc1>>CCOC(=O)C(CN1CCN(c2cc(=O)n(C)c(=O)n2C)CC1)c1ccccc1,,C1COCCO1,,CCN(CC)CC,,test
US20060235015A1,COCCN1C(=O)C(Cl)=C(c2ccccc2)C1=O.Nc1ccc(OC(F)F)cc1>>COCCN1C(=O)C(Nc2ccc(OC(F)F)cc2)=C(c2ccccc2)C1=O,,CN(C)C=O,,,,test
US20020165274A1,CC(C)(C)NO.COCOc1c(C(C)(C)C)cc(C=O)cc1C(C)(C)C>>COCOc1c(C(C)(C)C)cc(C=[N+]([O-])C(C)(C)C)cc1C(C)(C)C,,c1ccccc1,,,,test
US20150018422A1,COCOCc1cccc(Br)c1.CON(C)C(=O)C(F)(F)C(F)(F)F>>COCOCc1cccc(C(=O)C(F)(F)C(F)(F)F)c1,,C1CCOC1,,Cl,[Mg],test
US20090093465A1,ClCCl.O=C(O)c1ncncc1Br>>COC(=O)c1ncncc1Br,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US05798354,COC(=O)c1ccc(C#Cc2ccc(OCC3COC(C)(C)O3)c(C34CC5CC(CC(C5)C3)C4)c2)cc1>>COC(=O)c1ccc(C#Cc2ccc(OCC(O)CO)c(C34CC5CC(CC(C5)C3)C4)c2)cc1,,O=CO,,O,,test
US05129942,CCOC(=O)c1ccc(NN2C(=O)C(C)=C(C)C2=O)cc1S(N)(=O)=O.COc1cc(OC)nc(NC(=O)Oc2ccccc2)n1>>CCOC(=O)c1ccc(NN2C(=O)C(C)=C(C)C2=O)cc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1,,CC(=O)N(C)C,,C1CCC2=NCCCN2CC1,Cl,test
US20040242608A1,COC(=O)c1ccc(Cn2c(C)nc(OCc3ccc(F)cc3F)cc2=O)cc1>>Cc1nc(OCc2ccc(F)cc2F)cc(=O)n1Cc1ccc(C(=O)O)cc1,,C1COCCO1,O,CC(=O)O,[Na+].[OH-],test
US20050277670A1,CC(=O)c1ccc(N(Cc2ccsc2)C2CCN([C@H](C)CCNC(=O)c3c(C)ncnc3C)CC2)cc1.CON>>CON=C(C)c1ccc(N(Cc2ccsc2)C2CCN([C@H](C)CCNC(=O)c3c(C)ncnc3C)CC2)cc1,,CO,,Cl,CC(=O)[O-].[Na+],test
US20140148440A1,CC(C)(C)OC(=O)NC1CCc2nc(Br)sc2C1>>NC1CCc2nc(Br)sc2C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030232783A1,COC(C)(C)OC.OC[C@H]1O[C@@H](n2cnc3c(NC4CCOC4)ncnc32)[C@@H](O)[C@H]1O>>OC[C@H]1O[C@@H](n2cnc3c(NC4CCOC4)ncnc32)[C@@H](O)[C@H]1O.[CH2-]C(C)=O,,CN(C)C=O,CO,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040048880A1,CC(=O)Oc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OC1CCN(C(=O)C(F)(F)F)CC1>>O=C(N1CCC(Oc2cc3c(Nc4ccc(F)c(Cl)c4)ncnc3cc2O)CC1)C(F)(F)F,,CO,,Cl,O=C([O-])O.[Na+],test
US20110312905A1,BrCc1ccccc1.[O-][n+]1ccccc1O>>O=c1ccccn1OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080153870A1,CN1[C@H]2CC[C@@H]1C(c1nnc(-c3ccccc3)o1)[C@@H](c1ccc(Cl)cc1)C2.ClC(Cl)Cl>>CN1[C@H]2CC[C@@H]1[C@@H](c1nnc(-c3ccccc3)o1)[C@@H](c1ccc(Cl)cc1)C2.Cl,,ClC(Cl)Cl,,,,test
US04361563,CC1CC(=O)NN=C1c1ccc(NC2CC2)c([N+](=O)[O-])c1>>CC1CC(=O)NN=C1c1ccc(NC2CC2)c(N)c1,[Pd],CC(=O)O,,CCO,[H][H],test
US20130190289A1,CC(C)(C)OC(=O)N[C@H]1CCCNC1=O.CC(C)I>>CC(C)N1CCC[C@H](NC(=O)OC(C)(C)C)C1=O,,CS(C)=O,,[K+].[OH-],,test
US06391827B1,CC#COS(C)(=O)=O.Cn1c(Cl)c(-c2cc(O)c(Cl)cc2F)c(Br)c1C(F)(F)F>>C#CCOc1cc(-c2c(Br)c(C(F)(F)F)n(C)c2Cl)c(F)cc1Cl,,CC(=O)CC(C)C,,O,O=C([O-])[O-].[K+].[K+],test
US20110144095A1,CC(C)=CCn1c(C2CCN(N=O)CC2)nc2c1c(=O)n(C)c(=O)n2C>>CC(C)=CCn1c(C2CCN(N)CC2)nc2c1c(=O)n(C)c(=O)n2C,[Zn],CC(=O)O,O,,,test
US04499089,CC(C)SC1=C(C#N)C(c2ccccc2)(c2ccccc2)C(=O)N1.CN(C)CCCCl>>CC(C)SC1=C(C#N)C(c2ccccc2)(c2ccccc2)C(=O)N1CCCN(C)C,,C1COCCO1,,Cl,[H-].[Na+],test
US20120302563A1,CO/N=C/c1ccc2c(c1Cn1ccnc1)OCO2.COc1ccc(CNCC(OC)OC)cc1OC>>COc1cc2cnc3c(c2cc1OC)Cc1c-3cc2c(c1Cn1ccnc1)OCO2,,O,,Cl,[NH4+].[OH-],test
US06307056B1,O=C1Nc2cccc(I)c2/C1=C/c1ccc[nH]1.OB(O)c1ccc(O)cc1>>O=C1Nc2cccc(-c3ccc(O)cc3)c2/C1=C/c1ccc[nH]1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20160152624A1,BrCCBr.COc1ccc(-c2nc(C)c3c(n2)N(c2cccc(OCc4ccccc4)c2)C(=O)C3)cc1F>>COc1ccc(-c2nc(C)c3c(n2)N(c2cccc(OCc4ccccc4)c2)C(=O)C32CC2)cc1F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080027067A1,COC(=O)CBr.Oc1ccc(F)c(Cl)c1>>O=C(O)COc1ccc(F)c(Cl)c1,,CO,CS(C)=O,O,[K+].[OH-],test
US20090099156A1,CN1CCCC(CN2CCNCC2)C1.O=C(Cl)Oc1ccc(Cl)c(Cl)c1>>CN1CCCC(CN2CCN(C(=O)Oc3ccc(Cl)c(Cl)c3)CC2)C1,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US04087432,Nc1nc(Cl)c(Cl)cc1[N+](=O)[O-].Nc1ncc(Cl)cc1[N+](=O)[O-].O=C(Cl)C(F)(F)C(F)F>>Nc1nc(Cl)c(Cl)cc1[N+](=O)[O-].O=C(Nc1nc(Cl)c(Cl)cc1[N+](=O)[O-])C(F)(F)C(F)F,,C1CCOC1,,CCN(CC)CC,,test
US20020156081A1,Clc1ncnc2[nH]nc(Br)c12.OC1CCN(Cc2ccccc2)CC1>>Clc1ncnc2c1c(Br)nn2C1CCN(Cc2ccccc2)CC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130046000A1,CCOC(=O)C1=CCOC[C@H]1SC(C)=O>>CCOC(=O)C1=CCOC[C@H]1S,,CCO,,Cl,O=C([O-])O.[Na+],test
US20130274244A1,CC1(C)OCC(COc2ccn3c(C(=O)O)cnc3c2)O1.Cc1cccc(Cn2nc(C)c3c(N)cccc32)n1>>Cc1cccc(Cn2nc(C)c3c(NC(=O)c4cnc5cc(OCC6COC(C)(C)O6)ccn45)cccc32)n1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US04186205,BrB(Br)Br.COc1ccc(-c2nc3n(c2-c2ccc(OC)cc2)CCC3)cc1>>Br.Oc1ccc(-c2nc3n(c2-c2ccc(O)cc2)CCC3)cc1,,ClCCl,,,,test
US20080318981A1,C[C@H](O)c1nc(Br)ccc1F>>C[C@H](O)c1ncccc1F,[Pd],ClCCl,,CCN(CC)CC,[H][H],test
US20100144710A1,CCCCOc1ccc(C)nc1.O=C(OO)c1cccc(Cl)c1>>CCCCOc1ccc(C)[n+]([O-])c1,,ClCCl,,,,test
US20100029636A1,CCBr.CCCCOC(=O)Nc1ccc(-c2cnc3c(-c4cccc(N5CCNCC5)c4)cnn3c2N)cc1>>CCCCOC(=O)Nc1ccc(-c2cnc3c(-c4cccc(N5CCN(CC)CC5)c4)cnn3c2N)cc1,CCN(CC)CC,CN(C)C=O,,O,,test
US06114334,C=O.COc1ccccc1N1CCNCC1.Cn1c(N)cc(=O)n1-c1ccccc1>>COc1ccccc1N1CCN(Cc2c(N)n(C)n(-c3ccccc3)c2=O)CC1.O,,,,,,test
US20040082780A1,CC(C)(C)c1ccc(-c2cc(Cl)ncn2)cc1.COc1cccc(S)c1>>COc1cccc(Sc2cc(-c3ccc(C(C)(C)C)cc3)ncn2)c1,,CN(C)C=O,,[H-].[Na+],,test
US20020150936A1,CC(=O)OC(C)=O.Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1>>CC(=O)Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1,,CN(C)C=O,,CO,ClCCl,test
US05149357,CCOC(=O)CC(C)=O.O=C/C=C/c1ccccc1>>CCOC(=O)C1C(=O)C=CCC1c1ccccc1,,CCO,,Cl,[Na],test
US20110213061A1,CCCCOP(=O)(CC)CCCN>>CCP(=O)(O)CCCN,,CCCCO,O,,,test
US05389687,CCCN(CCC)C1CCc2cccc(Br)c2C1.CN(C)C=O>>CCCN(CCC)C1CCc2cccc(C=O)c2C1,,C1CCOC1,O,CCCCCC,[Li]CCCC,test
US20080090801A1,Cc1nc(NCC(C)(C)O)nc2c1cc(Br)c(=O)n2C1CCCC1.OB(O)c1cccc(O)c1>>Cc1nc(NCC(C)(C)O)nc2c1cc(-c1cccc(O)c1)c(=O)n2C1CCCC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030073836A1,Cn1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1C(=O)O.NCc1ccc(N2CCC3(CCCCC3)CC2)cc1>>Cn1cc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1C(=O)NCc1ccc(N2CCC3(CCCCC3)CC2)cc1,,C1CCOC1,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US05142056,C=O.OC(CCc1ccccc1)C(O)CCc1ccccc1>>c1ccc(CCC2OCOC2CCc2ccccc2)cc1,,CC(=O)O,,O=S(=O)(O)O,,test
US08877747B2,CS(=O)(=O)Cl.O=C1C(c2cnc3ccccc3c2)=C(c2cc(F)cc(F)c2)c2ccc(OCCCN3CCNCC3)cc21>>CS(=O)(=O)N1CCN(CCCOc2ccc3c(c2)C(=O)C(c2cnc4ccccc4c2)=C3c2cc(F)cc(F)c2)CC1,,ClCCl,,CCN(CC)CC,,test
US20140103319A1,Brc1ccc(I)cc1.Cc1ccccc1.OB(O)c1ccc2c(ccc3ccccc32)c1>>Brc1cccc(-c2ccc3c(ccc4ccc5ccccc5c43)c2)c1,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20040063170A1,COC(=O)c1ccc(Cc2ccccc2O[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)cc1>>O=C(O)c1ccc(Cc2ccccc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1,,CO,,[Na+].[OH-],,test
US20150191483A1,O=C(O)C1CCS(=O)(=O)CC1.O=S(=O)(c1ccc2c(c1)CCC2)C1(c2ccc(C(F)(C(F)(F)F)C(F)(F)F)cc2)CCNC1>>O=C(C1CCS(=O)(=O)CC1)N1CCC(c2ccc(C(F)(C(F)(F)F)C(F)(F)F)cc2)(S(=O)(=O)c2ccc3c(c2)CCC3)C1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100249123A1,CC(C)(C#N)c1cccc(N)c1.COc1ccc(C(=O)Cl)cc1OC>>COc1ccc(C(=O)Nc2cccc(C(C)(C)C#N)c2)cc1OC,,ClCCl,,CCN(CC)CC,,test
US20130143906A1,COC(=O)c1ccc(C)c(-n2c(C)nc(O)cc2=O)c1.COc1cccc(CBr)c1>>COC(=O)c1ccc(C)c(-n2c(C)nc(OCc3cccc(OC)c3)cc2=O)c1,,CN(C)C=O,,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US20080039452A1,CCOC(=O)CP(=O)(OCC)OCC.O=Cc1nccn1C(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)/C=C/c1nccn1C(c1ccccc1)(c1ccccc1)c1ccccc1,,C1CCOC1,,O,[H-].[Na+],test
US20120115852A1,COC(=O)C1CN(C(=O)OC(C)(C)C)CCN1Cc1cc(-c2ccc(Cl)cc2)ccc1[N+](=O)[O-]>>COC(=O)C1CN(C(=O)OC(C)(C)C)CCN1Cc1cc(-c2ccc(Cl)cc2)ccc1N,[Ni],C1CCOC1,,[H][H],,test
US05258513,C1CSCN1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCSC1,,C1COCCO1,O,,,test
US06329370B1,CC(=O)O.CCN(CC)C(=O)c1ccc(OC)c(OCc2ccccc2)c1C=O>>COc1ccc2c(c1O)C(O)OC2=O,,Cl,,,,test
US06169107A,CCOC(=O)c1cc2c(Cl)cc(O)cc2n1C.O=Cc1ccc(F)cc1>>CCOC(=O)c1cc2c(Cl)cc(Oc3ccc(C=O)cc3)cc2n1C,,CN(C)C=O,,[H-].[Na+],,test
US04925838,CS(=O)(=O)OC[C@@H]1C[C@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1.NC(=O)[C@@H]1CCCN1>>NC(=O)[C@@H]1CCCN1C[C@@H]1C[C@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1,,CN(C)C=O,,,,test
US20130338139A1,COc1ccc(Cn2c(=O)n3ncnc3c3cc(C(C)=O)cnc32)cc1.C[C@H]1CNC[C@@H](C)O1>>COc1ccc(Cn2c(=O)n3ncnc3c3cc(C(C)N4C[C@H](C)O[C@H](C)C4)cnc32)cc1,,CC#N,,CC(=O)O,[BH3-]C#N.[Na+],test
US20160184318A1,COc1ccc(Cn2cc(CCCC=O)nn2)cc1.Cc1nnn(Cc2cc(C(F)(F)F)ccc2/C=C/C(=O)N2CCC(N)CC2)n1>>COc1ccc(Cn2cc(CCCCNC3CCN(C(=O)/C=C/c4ccc(C(F)(F)F)cc4Cn4nnc(C)n4)CC3)nn2)cc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05945438,CSC(F)(F)C(O)(Cn1cncn1)c1ccc(F)cc1F.O=C(OO)c1cccc(Cl)c1>>CS(=O)C(F)(F)C(O)(Cn1cncn1)c1ccc(F)cc1F,,ClCCl,,O,,test
US20040242604A1,Cc1cc(N)ccc1Oc1cccc(C(=O)OC(C)(C)C)c1.O=c1[nH]cnc2cnc(F)cc12>>Cc1cc(Nc2ncnc3cnc(F)cc23)ccc1Oc1cccc(C(=O)OC(C)(C)C)c1,,CN(C)C=O,ClCCCl,CCN(CC)CC,O=S(Cl)Cl,test
US20130281299A1,CCCI.CCc1cc(C)cc(CC)c1-c1c(OCc2ccccc2)c(O)nn(C)c1=O>>CCc1cc(C)cc(CC)c1-c1c(OCc2ccccc2)c(OC)nn(C)c1=O,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030181726A1,COC(=O)Nc1ccc(C(CCNCc2ccccc2)c2ccc(NC(=O)OC)cc2)cc1.O=[N+]([O-])c1cc([C@@H]2CO2)ccc1OCc1ccccc1>>COC(=O)Nc1ccc(C(CCN(Cc2ccccc2)C[C@H](O)c2ccc(OCc3ccccc3)c(N)c2)c2ccc(NC(=O)OC)cc2)cc1,[Fe],O,,CCO,[Cl-].[NH4+],test
US05262390,Cc1nn(-c2ccc([N+](=O)[O-])cc2F)c(=O)n1C(F)F>>Cc1nn(-c2ccc(N)cc2F)c(=O)n1C(F)F,O=[Pt],CCO,,[H][H],,test
US20070106077A1,COC(=O)NCC=CC1=CNC(N)N1>>Nc1nc2ncccc2[nH]1,,[Na+],[OH-],,,test
US20100305070A1,CCOC(COc1c(C=O)cc(OC)cc1OC)OCC>>COc1cc(OC)c2oc(CO)cc2c1,,C1CCOC1,CCO,[BH4-].[Na+],,test
US04556655,C=C(C)C.Cc1ccc(S(=O)(=O)O[C@@H](C)C(=O)O)cc1>>Cc1ccc(S(=O)(=O)O[C@@H](C)C(=O)OC(C)(C)C)cc1,,ClCCl,,O=S(=O)(O)O,O=C([O-])[O-].[Na+].[Na+],test
US20040127574A1,CCOC(=O)CC(=O)c1ccc(Cl)nc1.FC(F)(F)c1ccc(CBr)cc1>>CCOC(=O)C(Cc1ccc(C(F)(F)F)cc1)C(=O)c1ccc(Cl)nc1,,COCCOC,O,[H-].[Na+],,test
US20030114668A1,CC1(C)COCCN1.Cl.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCN(CC#CCCl)C[C@H]1Cc1ccc2ccccc2c1>>CC1(C)COCCN1CC#CCN1CCN(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](Cc2ccc3ccccc3c2)C1.Cl.Cl,,CN(C)C=O,,[I-].[K+],,test
US20120252777A1,COC(=O)c1ccc(CBr)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>COC(=O)c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.[Br-],,Cc1ccccc1,,,,test
US20090186840A1,CC(=O)Cl.Oc1ccc(Br)cn1>>CC(=O)Oc1ccc(Br)cn1,,CCOCC,,CCN(CC)CC,,test
US05472966,CN.OCCCN1CC=C(c2cccc3ccccc23)CC1>>CNCCCN1CC=C(c2cccc3ccccc23)CC1,,CC#N,ClC(Cl)Cl,CCN(CC)CC,CS(=O)(=O)Cl,test
US05750720,Cc1cscc1C(O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>Cc1cscc1C(=O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1,O=[Mn]=O,ClCCl,,,,test
US20040167155A1,CC1c2ccccc2-c2ccccc2N1S(=O)(=O)c1ccc(O)c(C(=O)O)c1>>CC1c2ccccc2-c2ccccc2N1S(=O)(=O)c1ccc(O)c(CO)c1,,C1CCOC1,,,,test
US20060122394A1,CC1CCCN1.CCOC(=O)c1cnc(N2CCN(c3cc(-c4ccc(F)cc4)nc(Cl)n3)CC2)c(Cl)c1>>CCOC(=O)c1cnc(N2CCN(c3cc(-c4ccc(F)cc4)nc(N4CCCC4C)n3)CC2)c(Cl)c1,,CC(=O)N(C)C,,,,test
US20120302599A1,BrC(Br)(Br)Br.O=[N+]([O-])c1nn(Cc2ccccc2)cc1CO>>O=[N+]([O-])c1nn(Cc2ccccc2)cc1CBr,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US06087380,CCCCCCCCCOC(=O)Cl.COC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)N)cc1)n2C)c1ccccn1>>CCCCCCCCCOC(=O)NC(=N)c1ccc(NCc2nc3cc(C(=O)N(CCC(=O)OC)c4ccccn4)ccc3n2C)cc1,,CO,ClCCl,Cl,,test
US20120220586A1,[N-]=[N+]=NCc1cc2cccc(Cl)c2nc1-c1cc(F)ccc1C(F)(F)F>>NCc1cc2cccc(Cl)c2nc1-c1cc(F)ccc1C(F)(F)F,[Pd],,,CO,,test
US20130005771A1,COc1ccc(C=O)cc1[N+](=O)[O-].O=C(O)CC(=O)O>>COc1ccc(C=CC(=O)O)cc1[N+](=O)[O-],,c1ccncc1,,C1CCNCC1,,test
US20070124152A1,O=C1CCCN1CCO>>O=CCN1CCCC1=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US09416102B2,CC[Si](CC)(CC)OC(C)(C)C(=O)CBr.COP(OC)OC>>CC[Si](CC)(CC)OC(C)(C)C(=O)CP(=O)(OC)OC,,Cc1ccccc1,,,,test
US20020169155A1,CC(C)(C)OC(=O)N1CCC(=O)C(C)(C)C1.Clc1ccc([Mg]Br)cc1>>CC(C)(C)OC(=O)N1CCC(O)(c2ccc(Cl)cc2)C(C)(C)C1,,C1CCOC1,,,,test
US20020006943A1,CNOC.O=C(Cl)CCC(F)(F)F>>CON(C)C(=O)CCC(F)(F)F,,ClCCl,,Cl,c1ccncc1,test
US20110257100A1,CC(C)(C)OC(=O)N[C@@H](CCN)C(=O)O.O=Cc1ccc(-c2cc3nccc(Oc4ccc(NC(=O)NC5CC5)cc4F)c3s2)nc1>>CC(C)(C)OC(=O)N[C@H]1CCN(Cc2ccc(-c3cc4nccc(Oc5ccc(NC(=O)NC6CC6)cc5F)c4s3)nc2)C1=O,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04596816,CCOC(=O)CC(=O)OCC.Cc1nc(-c2ccc(Cl)cc2)c(CBr)o1>>Cc1nc(-c2ccc(Cl)cc2)c(CCC(=O)O)o1,,CN(C)C=O,O,[H-].[Na+],,test
US20040122057A1,CCOC(=O)CBr.COc1ccc(C(OC)C(=O)NCc2ccc(C#N)cc2)cc1O>>CCOC(=O)COc1cc(C(OC)C(=O)NCc2ccc(C#N)cc2)ccc1OC,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20130252937A1,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(B5OC(C)(C)C(C)(C)O5)ccc(F)c43)ccc21.Cc1cc(OCC(C)(C)CO)cc(C)c1Br>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(OCC(C)(C)CO)cc5C)ccc(F)c43)ccc21,,Cc1ccccc1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US04182758,CCOC(=O)N(O)CC(O)CP(=O)(O)O>>O=P(O)(O)CC(O)CNO,,CO,Cl,N,O,test
US05736487,CCC(=O)Cl.COC(=O)N(CO)c1ccc(OCc2nc3ccccc3s2)cc1C>>CCC(=O)OCN(C(=O)OC)c1ccc(OCc2nc3ccccc3s2)cc1C,,ClCCl,,O,c1ccncc1,test
US20160039788A1,C#CCCCCNC1CCC(=O)NC1=O.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C#CCCCCN(C(=O)OC(C)(C)C)C1CCC(=O)NC1=O,CN(C)c1ccncc1,CC#N,,,,test
US04293557,CC(Br)C(=O)NCCCOc1cccc(C(C)N2CCCC2)c1.NCCO>>CC(c1cccc(OCCCNC(=O)CCNCCO)c1)N1CCCC1,,CCO,,,,test
US20030232853A1,COC(=O)c1ccc2oc(C#N)cc2c1.O>>NC(=O)c1cc2cc(C(=O)O)ccc2o1,,O,,CO,,test
US20150031674A1,CSc1ncc2cc(-c3ccc(-c4cccc(C)n4)cc3C)c(=O)n(CC(=O)N3CCN(C(=O)OC(C)(C)C)CC3)c2n1.O=C(OO)c1cccc(Cl)c1>>Cc1cccc(-c2ccc(-c3cc4cnc(S(C)=O)nc4n(CC(=O)N4CCN(C(=O)OC(C)(C)C)CC4)c3=O)c(C)c2)n1,,ClCCl,,CC(=O)O,,test
US05380742,Cc1ccc(S(N)(=O)=O)cc1.Cc1sc(C)c(CCl)c1CCl>>Cc1ccc(S(=O)(=O)N2Cc3c(C)sc(C)c3C2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140309225A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.COc1ncc([N+](=O)[O-])cc1Br>>COc1ncc([N+](=O)[O-])cc1C(C)=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(=O)N(C)C,,O=C([O-])O.[Na+],,test
US20080319005A1,COC(=O)Cc1ccc(Nc2ccncc2[N+](=O)[O-])cc1>>COC(=O)Cc1ccc(Nc2ccncc2N)cc1,[Ni],CO,,,,test
US05312951,C(#Cc1ccccc1)c1ccccc1.Cc1cp(-c2ccccc2)cc1C>>CC1=C(c2ccccc2)P2CC1(C)C(c1ccccc1)=C2c1ccccc1,,Cc1ccccc1,,,,test
US20110144099A1,CC(C)(CNc1c([N+](=O)[O-])cnc2cc(OCc3ccccc3)ccc12)NC(=O)OC(C)(C)C>>CC(C)(CNc1c(N)cnc2cc(OCc3ccccc3)ccc12)NC(=O)OC(C)(C)C,[Pt],CC#N,,[H][H],,test
US20120258948A1,BrCCCOc1ccc(Br)cc1.FC1(F)CCNCC1>>FC1(F)CCN(CCCOc2ccc(Br)cc2)CC1,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US04638067,CCN(CC(N)=S)C(C)=O.CCOC(=O)c1cn(CC)c2cc(C(=O)CBr)c(F)cc2c1=O>>CCOC(=O)c1cn(CC)c2cc(-c3csc(CN(CC)C(C)=O)n3)c(F)cc2c1=O,,CCO,,,,test
US20080019915A1,C=C[Sn](CCCC)(CCCC)CCCC.CC(C)(C)C(=O)Nc1ccc(Br)cn1>>C=Cc1ccc(NC(=O)C(C)(C)C)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20080096874A1,CCO.COC(=O)C(C)=C1CCN(C(=O)OC(C)(C)C)CC1.Cl>>CCOC(=O)C(C)=C1CCNCC1.Cl,,CCO,,C1COCCO1,,test
US20140051672A1,CC(C)(C)[Si](C)(C)Cl.C[C@H](O)[C@@H]1CC(=O)CC(C)(C)N1>>C[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1CC(=O)CC(C)(C)N1,,CN(C)C=O,O,c1c[nH]cn1,,test
US20060270690A1,CCN(c1cccc(C(=O)C=CN(C)C)c1)S(=O)(=O)c1ccccc1.N#Cc1cn[nH]c1N>>CCN(c1cccc(-c2ccnc3c(C#N)cnn23)c1)S(=O)(=O)c1ccccc1,,CC(=O)O,,CCOC(C)=O,,test
US04909829,O=c1n(CCCF)nnn1-c1ccc([N+](=O)[O-])cc1F>>Nc1ccc(-n2nnn(CCCF)c2=O)c(F)c1,[Fe],CC(=O)O,O,,,test
US20140371278A1,COC(=O)c1cc2scnc2c(F)c1Nc1ccc(I)cc1F>>O=C(O)c1cc2scnc2c(F)c1Nc1ccc(I)cc1F,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20040082571A1,C[C@@H]1CN(c2ccc(Cl)cc2)CCN1.O=C(Cl)CCl>>C[C@@H]1CN(c2ccc(Cl)cc2)CCN1C(=O)CCl,,ClCCl,,CCN(CC)CC,,test
US20060173053A1,CCCCCCCC/C=C\CCCCCCCCO.O=C(Cl)c1cccnc1>>O=C(O)c1cccnc1,,CCCCCC,,Cl,c1ccncc1,test
US06008230,CCOC(=O)c1cnc2c(NC(=O)c3c(Cl)cccc3Cl)cccc2c1CBr.Sc1ncc[nH]1>>CCOC(=O)c1cnc2c(NC(=O)c3c(Cl)cccc3Cl)cccc2c1CSc1ncc[nH]1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090111860A1,CCC(C(=O)OC(C)C)C(=O)C(C)NC(=O)OC(C)(C)C.NN>>CCc1c(C(C)NC(=O)OC(C)(C)C)[nH][nH]c1=O,,CO,,O,,test
US20050032786A1,CC(C)(C)OC(=O)NCc1cccc(C#N)n1.COC(=O)c1ccccc1S>>CC(C)(C)OC(=O)NCc1cccc(-c2nc(=O)c3ccccc3s2)n1,,Cc1ccccc1,,CCN(CC)CC,,test
US20130172292A1,Brc1c[nH]c2cccnc12.CI>>Cn1cc(Br)c2ncccc21,,CN(C)C=O,O,[H-].[Na+],,test
US20030092677A1,Cc1nccn1-c1cccc(C(=O)CC(=O)Nc2cc(-c3ccc(F)cc3F)ccc2NC(=O)OC(C)(C)C)c1>>Cc1nccn1-c1cccc(C2=Nc3ccc(-c4ccc(F)cc4F)cc3NC(=O)C2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090275592A1,CC(C)(C)OC(=O)N[C@H](CCn1cc(-c2ccc3c(c2)CC(=O)N3)cn1)Cc1ccc(Cl)cc1.O=C(O)C(F)(F)F>>N[C@H](CCn1cc(-c2ccc3[nH]c(=O)oc3c2)cn1)Cc1ccc(Cl)cc1,,ClCCl,,,,test
US20050059687A1,COc1ccc(S(=O)(=O)N2CCN(CC(=O)O)CC2)cc1.NC(=O)c1ccccc1N>>COc1ccc(S(=O)(=O)N2CCN(CC(=O)Nc3ccccc3C(N)=O)CC2)cc1,,CC#N,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060148858A1,COC(=O)Cc1cccc(C)c1O.OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1C1CCCCC1>>Cc1cccc(CC(=O)O)c1OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1C1CCCCC1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US04692449,O=C1C=CC(=O)c2nccnc21.c1ccc(CN2CCNCC2)cc1>>O=C1C=C(N2CCN(Cc3ccccc3)CC2)C(=O)c2nccnc21,,C1COCCO1,,,,test
US04806549,CCCC(=O)c1cnc2c(OC)cccc2c1Cl.Cc1ccccc1N>>CCCC(=O)c1cnc2c(OC)cccc2c1Nc1ccccc1C,,C1COCCO1,,,,test
US20080182868A1,CC1(C)OB(c2cccc(S(N)(=O)=O)c2)OC1(C)C.Nc1ncc(Br)c2scc(-c3ccc(F)c(Cl)c3)c12>>Nc1ncc(-c2cccc(S(N)(=O)=O)c2)c2scc(-c3ccc(F)c(Cl)c3)c12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20140073626A1,CN(C)C(=O)C(C#N)=Cc1ccc(Nc2cnc3c(n2)c(C(=O)NC(C)(C)C)cn3COCC[Si](C)(C)C)cc1>>CN(C)C(=O)C(C#N)=Cc1ccc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)cc1,,CCO,ClCCl,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US04145432,CCOC(=O)C1=C(C)NC(CO)=C(C(=O)OCC)C1c1ccccc1Cl>>CCOC(=O)C1=C(C)NC(C=O)=C(C(=O)OCC)C1c1ccccc1Cl,,c1ccncc1,,Cc1ccc(S(=O)(=O)Cl)cc1,,test
US20130327251A1,CCCCCCCCCCCCCCCCCCOc1cc(OCCCCCCCCCCCCCCCCCC)cc(C(C(=O)OC)C(=O)OC)c1.CCCCCCCCCCCCCCCCCCOc1ccc(C(CO)CO)cc1>>CCCCCCCCCCCCCCCCCCOc1cc(OCCCCCCCCCCCCCCCCCC)cc(C(CO)CO)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04004912,C=CCN1CCC(O)N(c2nnc(C3CCCCC3)s2)C1=O.O=C(OC(=O)C1CCCCC1)C1CCCCC1>>C=CCN1CCC(OC(=O)C2CCCCC2)N(c2nnc(C3CCCCC3)s2)C1=O,,c1ccccc1,,Cc1ccccc1S(=O)(=O)O,,test
US04035376,CCOC(=O)C(C)(C(=O)OCC)c1ccc(C(=O)c2ccc3ccccc3c2)cc1>>CC(C(=O)O)c1ccc(C(=O)c2ccc3ccccc3c2)cc1,,O,,[Na+].[OH-],,test
US20130225552A1,CC(C)(C#N)c1nccnc1N[C@@H]1C[C@@H](Nc2nc3ccccc3s2)C1.O=S(=O)(O)O>>CC1(C)C(=O)N([C@@H]2C[C@@H](Nc3nc4ccccc4s3)C2)c2nccnc21,,O,O=S(=O)(O)O,CCOC(C)=O,[Na+].[OH-],test
US20100273744A1,COC(=O)c1ccc(Oc2ccccc2)cc1C(F)(F)F>>O=C(O)c1ccc(Oc2ccccc2)cc1C(F)(F)F,,CCO,,[Na+].[OH-],,test
US20070054897A1,O=C(OCc1ccccc1)[C@H]1CCCN1Cc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1>>O=C(O)[C@H]1CCCN1Cc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1,[Pd],CO,,,,test
US20050009846A1,CC[C@@H](NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(O)C(C)C>>CC[C@@H](N)C(O)C(C)C,,ClCCl,,O=C(O)C(F)(F)F,,test
US05219871,BrP(Br)Br.OCCc1ccc(Cl)cc1>>Clc1ccc(CCBr)cc1,,ClC(Cl)(Cl)Cl,,,,test
US20140228368A1,Cc1ccc(C2C(COc3cc(N(Cc4nnc(C)s4)C(=O)OC(C)(C)C)nc(C)n3)C2OC(C)(C)C)nc1>>Cc1ccc(C2C(COc3cc(NCc4nnc(C)s4)nc(C)n3)C2OC(C)(C)C)nc1,,O=C(O)C(F)(F)F,,,,test
US20150158851A1,N#Cc1cccc(CBr)c1.O=[N+]([O-])c1cn[nH]c1>>N#Cc1cccc(Cn2cc(N)cn2)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20050131012A1,Clc1cccc(SSc2cccc(Cl)c2Cl)c1Cl.NC(=O)c1cc2ncccc2[nH]1>>NC(=O)c1[nH]c2cccnc2c1Sc1cccc(Cl)c1Cl,,CN(C)C=O,,,,test
US20150119362A1,CCc1cc(Cl)nc(-c2cccc(Cl)c2)n1.NC(=O)Cc1ccc(N)cc1>>CCc1cc(Nc2ccc(CC(N)=O)cc2)nc(-c2cccc(Cl)c2)n1,C1COCCO1,CC(=O)O,,Cl,O=C([O-])O.[Na+],test
US20120071481A1,N[C@H]1CCC[C@@H](O)C1.O=C(Cl)c1noc(-c2ccc(C(F)(F)F)c(F)c2)c1CCl>>O=C(N[C@H]1CCC[C@@H](O)C1)c1noc(-c2ccc(C(F)(F)F)c(F)c2)c1CCl,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20080306115A1,Cc1c(C(=O)Nc2ccc(OC(F)(F)F)cc2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(O)cc1.O=S(=O)(Cl)CCC(F)(F)F>>Cc1c(C(=O)Nc2ccc(OC(F)(F)F)cc2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1,,ClCCl,,,,test
US06028032,COCC1=C(c2ccccc2)C(=O)N(C(C)(C)C(=O)OC(C)(C)C)CO1>>COCC1=C(c2ccccc2)C(=O)N(C(C)(C)C(=O)O)CO1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080242687A1,CCOC(=O)C(Cl)C(=O)OCC.COc1ccccc1O>>CCOC(=O)C(Oc1ccccc1OC)C(=O)OCC,,CCO,,[Na],,test
US20110046132A1,CCOC(=O)c1cnn(-c2nc3cc(SC(C)(C)C)c(Cl)cc3n2COCCOC)c1.O=[N+]([O-])c1ccccc1SCl>>CCOC(=O)c1cnn(-c2nc3cc(SSc4ccccc4[N+](=O)[O-])c(Cl)cc3n2COCCOC)c1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20140309208A1,COc1c(Nc2cccc3nn[nH]c23)c(=O)c1=O.Cc1ccc(C(N)C2(C)COC2)o1>>Cc1ccc(C(Nc2c(Nc3cccc4nn[nH]c34)c(=O)c2=O)C2(C)COC2)o1,,CO,,,,test
US20020006937A1,O=C(NCc1ccc(Cl)cc1)c1cnc2sc(CN3CCOCC3)cc2c1O.OCc1cccnc1>>O=C(NCc1ccc(Cl)cc1)c1cn(Cc2cccnc2)c2sc(CN3CCOCC3)cc2c1=O,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110319378A1,CC[C@@H](CCC#N)N1C(=O)[C@@H](CC(=O)OC(C)(C)C)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1>>CC[C@@H](CCC#N)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150183799A1,COc1cc(C)c2[nH]c(=O)c3sccc3c2c1-c1ccc(C(C)CN(C)C(=O)OC(C)(C)C)c(F)c1.Cl>>CNCC(C)c1ccc(-c2c(OC)cc(C)c3[nH]c(=O)c4sccc4c23)cc1F.Cl,,CCOCC,,,,test
US20100174065A1,C=CC(=O)OC(C)(C)C.CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCNCC4)no2)cc1Cl>>CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CCN(CCC(=O)O)CC4)no2)cc1Cl,,CO,,CCN(C(C)C)C(C)C,Cl,test
US20090036448A1,Cc1nc(N[C@@H]2CC[C@H](N)CC2)cc(N(C)C)n1.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(O)C(F)(F)F>>Cc1nc(N[C@@H]2CC[C@H](NC(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC2)cc(N(C)C)n1.O=C(O)C(F)(F)F,,CN(C)C=O,CS(C)=O,c1ccncc1,,test
US06348583B1,COC1(OC)C=CC(C(Cl)(c2ccccc2)c2ccccc2)=CC1.OCCOCCOCCOCCOCCOCCO>>COC1(OC)C=CC(C(c2ccccc2)(c2ccccc2)C(O)COCCOCCOCCOCCOCCO)=CC1,,c1ccncc1,,,,test
US20070032530A1,Cc1nc(-c2ccc(F)cc2)ccc1CCl.Oc1ccc(CCCCn2ccnn2)cc1>>Cc1nc(-c2ccc(F)cc2)ccc1COc1ccc(CCCCn2ccnn2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20130150343A1,CC(C)(C)c1cc(NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCCCC5)n4c3)c3ccccc32)n(-c2cnn(CCCO)c2)n1.CS(=O)(=O)Cl>>CC(C)(C)c1cc(NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCCCC5)n4c3)c3ccccc32)n(-c2cnn(CCCOS(C)(=O)=O)c2)n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070093488A1,CC(C)(C)OC(=O)N1CCC(CC(=O)O)CC1.CC(C)CNc1ccc(S(=O)(=O)Oc2ccc3nc(N)sc3c2)cc1>>CC(C)CNc1ccc(S(=O)(=O)Oc2ccc3nc(NC(=O)CC4CCN(C(=O)OC(C)(C)C)CC4)sc3c2)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130225620A1,Nc1cc(F)c(Br)cc1[N+](=O)[O-]>>Nc1cc(F)c(Br)cc1N,,CCO,,Cl[Sn]Cl,,test
US20150087646A1,Cc1ccc(CNC(=O)C(F)(F)F)c(C)c1-c1nn(-c2ccc(C(F)(F)F)cc2)c(=O)[nH]1>>Cc1ccc(CN)c(C)c1-c1nn(-c2ccc(C(F)(F)F)cc2)c(=O)[nH]1,,C1CCOC1,,[K+].[OH-],,test
US20050014754A1,O=C(c1ccc(F)cc1)c1ccn2ccccc12>>Fc1ccc(Cc2ccn3ccccc23)cc1,,C1CCOC1,,B,,test
US20110105461A1,COc1cc(SC)ccc1C(C)=O>>CSc1ccc(C(C)=O)c(O)c1,,ClCCl,,BrB(Br)Br,,test
US20160257668A1,CC(C)(C)OC(=O)c1ccc(NC(=O)C2C(OC3CCN(C(=O)OC(C)(C)C)CC3)CC(c3ccccc3)CN2C(=O)/C=C/c2cc(Cl)ccc2-n2cnnn2)cc1>>O=C(O)c1ccc(NC(=O)C2C(OC3CCNCC3)CC(c3ccccc3)CN2C(=O)/C=C/c2cc(Cl)ccc2-n2cnnn2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140206663A1,C=O.CC1C(=O)NN=C2COc3cc(-c4ccccc4F)c(NC4(C)CNC4)cc3N21>>CC1C(=O)NN=C2COc3cc(-c4ccccc4F)c(NC4(C)CN(C)C4)cc3N21,,CC(=O)O,CO,O,[BH3-]C#N.[Na+],test
US20070078184A1,CCOC(=O)c1ccc(-c2ccc(OC[C@@H](C)NC(=O)OC(C)(C)C)cc2)cc1>>CCOC(=O)c1ccc(-c2ccc(OC[C@@H](C)N)cc2)cc1,,CCO,,Cl,,test
US20050119279A1,CC(=O)Cl.CCOC(=O)[C@@H]1CSC2(CN3C(=O)N(c4cc(Cl)cc(Cl)c4)C(=O)[C@@]3(c3ccc(C#N)cc3)C2)N1>>CCOC(=O)[C@H]1CSC2(CN3C(=O)N(C)C(=O)[C@]3(CC)C2)N1C(C)=O,,CC#N,,,,test
US20120196863A1,CC1(c2cccc(Br)c2)COCC(N)=N1.OB(O)c1ccc(F)cc1F>>CC1(c2cccc(-c3ccc(F)cc3F)c2)COCC(N)=N1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])O.[Na+],,test
US20100137250A1,O=Cc1ccc(S(=O)(=O)c2ccccc2)cc1>>O=S(=O)(c1ccccc1)c1ccc(CO)cc1,,CCOC(C)=O,,C1CCOC1,[BH4-].[Na+],test
US20140357661A1,COC(=O)/C=C/c1cc(F)c(C2NC(C)(C)Cc3c2[nH]c2ccccc32)c(F)c1.C[C@H](CF)COS(=O)(=O)C(F)(F)F>>COC(=O)/C=C/c1cc(F)c(C2c3[nH]c4ccccc4c3CC(C)(C)N2C[C@H](C)CF)c(F)c1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20100022761A1,N#CCC(O)c1ccc2ccc(OS(=O)(=O)c3ccccc3)c(Br)c2n1>>NCCC(O)c1ccc2ccc(OS(=O)(=O)c3ccccc3)c(Br)c2n1,,C1CCOC1,,,,test
US04500343,CC(C)(C)c1cc(N)no1.CC(CCCl)C(=O)Cl>>CC(CCCl)C(=O)Nc1cc(C(C)(C)C)on1,,CCOC(C)=O,,CCN(CC)CC,,test
US20100266714A1,Cc1ccc(-c2cc(C(=O)OC(C)(C)C)cc(-c3nnc(C4CC4)n3C)c2)nc1>>Cc1ccc(-c2cc(C(=O)O)cc(-c3nnc(C4CC4)n3C)c2)nc1,,CO,,Cl,O=C(O)C(F)(F)F,test
US20160229816A1,CC(=O)Cl.CNc1ccc(C=O)cc1-c1cccc(C(F)(F)F)c1>>CC(=O)N(C)c1ccc(C=O)cc1-c1cccc(C(F)(F)F)c1,,ClCCl,,O,c1ccncc1,test
US04282388,CO[C@H]1CCCC[C@H]1O.Fc1ccccc1CCl>>CO[C@H]1CCCC[C@H]1OCc1ccccc1F,,CS(C)=O,,O,[Na+].[OH-],test
US06323199B1,COc1ccc(F)cc1C1(CC(O)(C(=O)Nc2ccc3c(c2)COC3=O)C(F)(F)F)CC1>>O=C1OCc2cc(NC(=O)C(O)(CC3(c4cc(F)ccc4O)CC3)C(F)(F)F)ccc21,,ClCCl,,BrB(Br)Br,O,test
US20100144801A1,O=C(Oc1ccc([N+](=O)[O-])cc1)N(Cc1ccccc1)c1ccccc1.OCc1nccn1Cc1ccccc1>>O=C(OCc1nccn1Cc1ccccc1)N(Cc1ccccc1)c1ccccc1,,CN(C)C=O,O,[H-].[Na+],,test
US20130317004A1,C1COCCN1.OC[C@H]1CO1>>OC[C@H](O)CN1CCOCC1,,CCO,,,,test
US20020052504A1,Nc1ccc(OC2CC2)c(CO)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1ccc(OC2CC2)c(CO)c1)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20150274747A1,[N-]=[N+]=NC1COC2C(OCCOCc3ccccc3)COC12>>NC1COC2C(OCCO)COC12,[Pd],CO,,,,test
US20100298290A1,CC(C)(C)OC(=O)N1CCOc2ccc(-c3cnc(N)c([N+](=O)[O-])c3)cc2C1>>CC(C)(C)OC(=O)N1CCOc2ccc(-c3cnc(N)c(N)c3)cc2C1,[Pd],CO,,,,test
US20080214860A1,CCOC(=O)CBr.OCCOc1ccc(C(=C(CCCl)c2ccccc2)c2ccccc2)cc1>>CCOC(=O)COCCOc1ccc(C(=C(CCCl)c2ccccc2)c2ccccc2)cc1,,C1CCOC1,C1CCOC1,[H-].[Na+],,test
US20100016319A1,O=C(CCl)NCO.Oc1ccc(F)cc1F>>O=C(CCl)NCc1cc(F)cc(F)c1O,,CC(=O)O,,O=S(=O)(O)O,,test
US04857527,C/C(N)=C/C(=O)NCCN1CCOCC1.O=C(C=Cc1cccc([N+](=O)[O-])c1)c1ccccc1>>Cc1nc(-c2ccccc2)cc(-c2cccc([N+](=O)[O-])c2)c1C(=O)NCCN1CCOCC1,,Cc1ccccc1,,,,test
US20020147181A1,N#Cc1ccc(Nc2nc(Cl)nc(Cc3c(Cl)cccc3Cl)n2)cc1.NCC(N)=O>>N#Cc1ccc(Nc2nc(Cc3c(Cl)cccc3Cl)nc(NCC(N)=O)n2)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20050288346A1,CCCc1c(OCCCCNc2ccc(-c3nn[nH]n3)cc2)ccc(C(C)=O)c1O.Cl>>CCCc1c(OCCCCNc2ccc(-c3nn[nH]n3)cc2)ccc(C(C)=O)c1O.Cl,,CCOCC,ClCCl,,,test
US20150376130A1,COC(=O)c1cccnc1F.Nc1ccccc1F>>COC(=O)c1cccnc1Nc1ccccc1F,,ClCCl,,,,test
US20060014761A1,CC(C)(C)OC(=O)N1CCNCC1.CS(=O)(=O)OCc1ccc(F)c([N+](=O)[O-])c1>>CC(C)(C)OC(=O)N1CCN(Cc2ccc(F)c([N+](=O)[O-])c2)CC1,,CCOC(C)=O,,,,test
US20100173886A1,CC(C)CCN.NC(=O)c1ccc(Oc2ncc(C=O)c3ccccc23)cc1>>CC(C)CCNCc1cnc(Oc2ccc(C(N)=O)cc2)c2ccccc12,,CN(C)C=O,,O,[BH4-].[Na+],test
US20050119320A1,CCOC(=O)CN=C=O.Cc1nc(N)sc1-c1ccc(S(=O)(=O)N(C)C)cc1>>CCOC(=O)CNC(=O)Nc1nc(C)c(-c2ccc(S(=O)(=O)N(C)C)cc2)s1,,CN(C)C=O,,,,test
US20060183791A1,Cc1cc(N)ccc1NC(=O)C(C)(C)C.Cc1nn(C)c(Oc2ccc(Cl)cc2)c1C=O>>Cc1cc(NCc2c(C)nn(C)c2Oc2ccc(Cl)cc2)ccc1NC(=O)C(C)(C)C,,CC#N,CO,CC(=O)O,[BH3-]C#N.[Na+],test
US20080058356A1,CCOC(=O)CC(=O)c1ccco1.N=C(N)c1ccccn1>>Oc1ccnc(-c2ccccn2)n1,,CCCCO,,CC(C)(C)[O-].[K+],,test
US20150210688A1,C=O.COC(=O)c1cc(-c2nc3c([nH]2)CCNCC3)c(C2CCC2)cc1C>>COC(=O)c1cc(-c2nc3c([nH]2)CCN(C)CC3)c(C2CCC2)cc1C,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20030096826A1,CCOC(OCC)[C@H](CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccc(NC(=O)CCCN(C)C)cc1OCc1ccccc1>>CCOC(OCC)[C@H](CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccc(NC(=O)CCCN(C)C)cc1O,[Pd],C1CCOC1,CCO,,,test
US20100286112A1,CC(C)(C)[Si](C)(C)Cl.COc1ccc(NCc2ccc(O)cc2F)cc1>>COc1ccc(NCc2ccc(O[Si](C)(C)C(C)(C)C)cc2F)cc1,,CN(C)C=O,,c1c[nH]cn1,,test
US06576787B1,C1CCOC1.C=CC(=O)Cl.CCN(CC)CC>>CCCCCCCCCC,,C1CCOC1,,,,test
US20150344471A1,CC(C)(C)OC(=O)NCCOc1ccc(Br)nc1.CN>>CNc1ccc(OCCNC(=O)OC(C)(C)C)cn1,,O,,,,test
US20140206618A1,Cc1c([C@H]2CN3CCN(C(=O)OC(C)(C)C)C[C@@H]3CO2)ccc(F)c1C#N>>Cc1c([C@H]2CN3CCNC[C@@H]3CO2)ccc(F)c1C#N,,O=C(O)C(F)(F)F,,,,test
US05219863,CCOCC.CCc1cc(OCc2ccc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc2)c2nc(OCCO)ccc2n1>>CCOC(=O)COc1ccc2nc(CC)cc(OCc3ccc(-c4ccccc4-c4nnn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc3)c2n1,,C1CCOC1,,[H][H],[H-].[Na+],test
US20080153887A1,CC(C)(C)[Si](C)(C)OCC#CC(=O)c1ccccc1>>CC(C)(C)[Si](C)(C)OCCCC(=O)c1ccccc1,[Pd],CCOC(C)=O,,,,test
US20070259881A1,C=CCn1c(COCC)nc2c(Cl)nc3ccccc3c21.C=O.CNO>>CCOCc1nc2c(Cl)nc3ccccc3c2n1CC1CCN(C)O1,,Cc1ccccc1,,Cl,O=C([O-])O.[Na+],test
US05852014,COC(=O)c1c(Cl)[nH]c2ccccc12.NCCCBr>>COC(=O)c1c2n(c3ccccc13)CCCN2,,C1CCOC1,Cc1ccccc1,[H-].[Na+],,test
US20050085465A1,Clc1ncnc2cc3c(cc12)OCO3.Oc1cnc2[nH]ccc2c1>>c1nc(Oc2cnc3[nH]ccc3c2)c2cc3c(cc2n1)OCO3,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20070093496A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)CNCc1ccc(F)cc1>>COC(=O)CN(Cc1ccc(F)cc1)C(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,C1CCOC1,CCN(CC)CC,test
US05817766,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.CCCCCc1cc(O)c2c(c1)OC(C)(C)C(CCCO)C2C>>CCCCCc1cc2c(c(O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)c1)C(C)C(CCCO)C(C)(C)O2,,CCOC(C)=O,,CN(C)C=O,[H-].[Na+],test
US20120028961A1,NC(=O)c1ccc2ncccc2c1>>N#Cc1ccc2ncccc2c1,,ClCCl,,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US20110129463A1,CC(=O)O.Nc1ccccc1C(=O)O>>CC(=O)Nc1ccccc1C(=O)O,,CC(=O)O,,CC(=O)OC(C)=O,,test
US06458830B1,C=Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1.CC[C@@H]1CN2CC[C@@H]1C[C@@H]2[C@H](Oc1nnc(O[C@H](c2ccnc3ccc(OC)cc23)[C@H]2C[C@@H]3CCN2C[C@@H]3CC)c2ccccc12)c1ccnc2ccc(OC)cc12.O>>OC[C@@H](O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,CC(C)(C)O,,O=S([O-])[O-].[Na+].[Na+],,test
US04665203,CCCc1c(OCc2ccccc2)ccc2c(=O)cc(C=CC(=O)OCC)oc12>>CCCc1c(O)ccc2c1OC(CCC(=O)OCC)CC2,[Pd],CC(=O)O,,,,test
US20080318989A1,Fc1cnc(Cl)nc1Cl.Nc1ccccc1NC(=O)C1CC1>>O=C(Nc1ccccc1Nc1nc(Cl)ncc1F)C1CC1,,CCO,,CCN(C(C)C)C(C)C,,test
US20060052378A1,CI.Oc1cccc2ccc(Br)cc12>>COc1cccc2ccc(Br)cc12,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05144045,C=C(CCCCCCCCCCCCCCCC)CC(CO)CO.CCCCCCCCCCCCCCCCBr>>C=C(CCCCCCCCCCCCCCCC)CC(CO)COCCCCCCCCCCCCCCCC,,CN(C)C=O,,[H-].[Na+],,test
US05344958,COc1cccc(C(=O)NNC(C)(C)C)c1C.Cc1cc(C)cc(C(=O)Cl)c1>>COc1cccc(C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C)c1C,,ClCCl,O,[Na+].[OH-],,test
US04710585,CCC(C)CCCCCOc1ccc(OCc2ccccc2)cc1>>CCC(C)CCCCCOc1ccc(O)cc1,[Pd],CCO,,[H][H],,test
US20110294776A1,CCOC(=O)c1cc(Br)c[nH]1.O=C=NS(=O)(=O)Cl>>CCOC(=O)c1cc(Br)c(C#N)[nH]1,,CC#N,,,,test
US04859684,CC(=O)Cl.Nc1cc(C(=O)c2ccccc2)ccc1[N+](=O)[O-]>>CC(=O)Nc1cc(C(=O)c2ccccc2)ccc1[N+](=O)[O-],,ClCCl,,,,test
US20070043040A1,C1COCCN1.C=O.CCO.Oc1ccccc1>>CCCCCC.CCOC(C)=O,,CCO,,,,test
US20070244131A1,O=C(OCc1ccccc1)N1CCCC(c2nnn[nH]2)C1>>C1CNCC(c2nnn[nH]2)C1,[Pd],CO,,[H][H],,test
US20100197655A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.N#Cc1cc(S(=O)(=O)Nc2ncc(Cl)s2)ccc1Oc1ccc(F)cc1I>>N#Cc1cc(S(=O)(=O)Nc2ncc(Cl)s2)ccc1Oc1ccc(F)cc1-c1cn[nH]c1,,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US05958970,CC1CCCCC1=O.O=C1CCC(=O)N1Br>>CC1(Br)CCCCC1=O,,ClC(Cl)(Cl)Cl,,,,test
US20070287711A1,COC(=O)c1cc(C(=O)N(C)C)cc(-c2cnc3c(c2)c(-c2ccccc2OC)nn3COCC[Si](C)(C)C)c1>>COc1ccccc1-c1nn(COCC[Si](C)(C)C)c2ncc(-c3cc(C(=O)O)cc(C(=O)N(C)C)c3)cc12,,CO,O,[Li+].[OH-],,test
US04362740,O=C1OCCC12Sc1ccc(S(=O)(=O)N3CCOCC3)cc1C2=O>>O=C1c2cc(S(=O)(=O)N3CCOCC3)ccc2SC12CC2,,O,,CC(C)=O,,test
US20140303121A1,Cc1noc(C)c1-c1cnc2c(-c3cnn(C(F)F)c3)cn(CC3(F)CCC4(CC3)OCCO4)c2c1>>Cc1noc(C)c1-c1cnc2c(-c3cnn(C(F)F)c3)cn(CC3(F)CCC(=O)CC3)c2c1,,C1CCOC1,,Cl,O=C([O-])[O-].[K+].[K+],test
US20040198982A1,Brc1ccc(Br)cc1.C[C@@H]1CN[C@H](C(=O)O)C1>>C[C@H]1C[C@@H](C(=O)O)N(c2cccc(Br)c2)C1,I[Cu]I,CN(C)C=O,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20140309207A1,CC(=O)N1CCC2(C1)CN(C(=O)C(F)(F)F)c1ccccc12.CN1CCNCC1.O=S(=O)(O)Cl>>CC(=O)N1CCC2(CNc3ccc(S(=O)(=O)N4CCN(C)CC4)cc32)C1,,ClCCl,O,CCN(C(C)C)C(C)C,,test
US20100105653A1,CN(C)C(=O)c1cc2cnc(Nc3ccc(CO)cn3)nc2n1C1CCCC1>>CN(C)C(=O)c1cc2cnc(Nc3ccc(C=O)cn3)nc2n1C1CCCC1,O=[Mn]=O,CO,ClCCl,,,test
US20030078260A1,COC(=O)c1ccc(-c2ccc3c(c2)CC[C@H](CNC[C@H](O)c2ccc(N)nc2)O3)cc1>>Nc1ccc([C@@H](O)CNC[C@H]2CCc3cc(-c4ccc(C(=O)O)cc4)ccc3O2)cn1,,C1CCOC1,CO,[Li+].[OH-],,test
US20140155398A1,COC(=O)c1cc(Cl)c(C(=O)OC)c(Cl)c1>>COC(=O)c1c(Cl)cc(CO)cc1Cl,,C1CCOC1,,CO,[BH4-].[Na+],test
US20090203657A1,COC(=O)c1cccc(C(=O)OC)n1>>COC(=O)c1cccc(C(=O)O)n1,,CO,,[K+].[OH-],,test
US04859662,Cc1[nH]cnc1C=C1CCc2[nH]c3c(F)cccc3c2C1=O>>Cc1[nH]cnc1CC1CCc2[nH]c3c(F)cccc3c2C1=O,[Pd],CCO,,[H][H],,test
US20060014953A1,CC(C)(C)OC(=O)N1CCn2nc(C(F)(F)F)nc2C1.O=CC1CC1>>CC(C)(C)OC(=O)N1CCn2nc(C(F)(F)F)nc2C1C(O)C1CC1,,Cc1ccccc1,,[Li]C(C)CC,,test
US20140315888A1,CN(C(=O)OC(C)(C)C)C1CNC1.Cc1nc2c3cc(Cl)cnc3nc(Cl)n2n1>>Cc1nc2c3cc(Cl)cnc3nc(N3CC(N(C)C(=O)OC(C)(C)C)C3)n2n1,,CN(C)C=O,,,,test
US06518282B1,CC(C)OCCO.O=S(=O)(Cl)c1ccc(Br)cc1>>CC(C)OCCOS(=O)(=O)c1ccc(Br)cc1,,ClCCl,O,CCN(CC)CC,Cl,test
US20030078260A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc2c(c1)CC[C@H](CNC[C@H](O)c1cccnc1)O2>>CC(C)(C)OC(=O)N(C[C@H]1CCc2cc([N+](=O)[O-])ccc2O1)C[C@H](O)c1cccnc1,,C1CCOC1,,,,test
US06649627B1,BrCc1ccccc1.CC(=O)c1cc(OCC2CO2)ccc1O>>CC(=O)c1cc(OCC2CO2)ccc1OCc1ccccc1,,CC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150210688A1,COC(=O)c1cc(I)c(C2CC2)cc1C>>Cc1cc(C2CC2)c(I)cc1C(=O)O,,CO,O,[Na+].[OH-],,test
US20130040930A1,C[C@@H]1CCS(=O)(=O)N1.Cc1cnc(N2CCN(C(=O)c3ccc(I)cc3)CC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(N4[C@H](C)CCS4(=O)=O)cc3)CC2)c(C)c1,[Cu]I,Cc1ccccc1,O,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US20130150344A1,CC1(C)C(=O)Nc2cccc(F)c21.O=[N+]([O-])O>>CC1(C)C(=O)Nc2ccc([N+](=O)[O-])c(F)c21,,O=S(=O)(O)O,,,,test
US20110136802A1,COc1cc(O)c2c(c1)S(=O)(=O)C[C@H]1[C@@]2(C)CC[C@H]2C(C)(C)CCC[C@@]21C.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1cc(OS(=O)(=O)C(F)(F)F)c2c(c1)S(=O)(=O)C[C@H]1[C@H]2CC[C@H]2C(C)(C)CCC[C@]12C,,ClCCl,,CCN(CC)CC,,test
US20140005397A1,Brc1ccccn1.COc1ccc(B(O)O)c(OC)n1>>COc1ccc(-c2ccccn2)c(OC)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20050032786A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCc1ccncc1>>CC(C)(C)OC(=O)NCCc1ccncc1,,C1CCOC1,,,,test
US20110269738A1,CC(C)Oc1ccc(-c2nnc(Br)s2)cc1C(F)(F)F.CCc1c(/C=C/OC)cccc1B1OC(C)(C)C(C)(C)O1>>CCc1c(/C=C/OC)cccc1-c1nnc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20060205802A1,COC(=O)Nc1ccc(F)c([N+](=O)[O-])c1.NCC1CCCCC1>>COC(=O)Nc1ccc(NCC2CCCCC2)c([N+](=O)[O-])c1,,CCO,,,,test
US20100087495A1,Cc1cc(C(=O)O)ccc1OC(C)C.O=S(Cl)Cl>>Cc1cc(C(=O)Cl)ccc1OC(C)C,,ClC(Cl)Cl,,,,test
US05912246,ClCc1cn2cc(Cl)ccc2n1.FC(F)(F)c1cccc(N2CCNCC2)c1>>FC(F)(F)c1cccc(N2CCN(Cc3cn4cc(Cl)ccc4n3)CC2)c1,,CO,ClCCl,,,test
US20100029615A1,CI.O=C(N[C@@H]1CCC[C@H](c2nc3ccccc3[nH]2)C1)c1ccc2c(c1)OCCO2>>Cn1c([C@H]2CCC[C@@H](NC(=O)c3ccc4c(c3)OCCO4)C2)nc2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150266857A1,CN1CCNCC1.O=S(=O)(c1ccccc1)n1cc(-c2ccc3oc(CCl)nc3c2)c2ccc(F)cc21>>CN1CCN(Cc2nc3cc(-c4cn(S(=O)(=O)c5ccccc5)c5cc(F)ccc45)ccc3o2)CC1,,CCOC(C)=O,CN(C)C=O,,,test
US04057556,COc1ccc(Sc2ccccc2C(=O)O)ccc1=O.N>>Nc1ccc(Sc2ccccc2C(=O)O)ccc1=O,,CO,,,,test
US04820719,FC(F)(F)c1cccc(S)c1.O=Cc1ccccc1CCCCCCCBr>>O=Cc1ccccc1CCCCCCCSc1cccc(C(F)(F)F)c1,,CN(C)C=O,Cc1ccccc1,CCN(CC)CC,,test
US20020120139A1,C1COCCO1.O=C(O)C=Cc1cncnc1>>COC(=O)C=Cc1cncnc1,,C1COCCO1,,Cl,O=C([O-])[O-].[K+].[K+],test
US20150376181A1,CC(C)(C)OC(=O)Nc1cc(/C=C/C2CC2)ncn1>>Nc1cc(/C=C/C2CC2)ncn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160194307A1,COc1cc(O)cc(OC)c1C=O.Cc1c(Br)cccc1CO>>COc1cc(OCc2cccc(Br)c2C)cc(OC)c1C=O,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110190266A1,Cn1ncnc1C1C(=O)C2=C(C(=O)O)CCCC2NC1c1ccc(F)cc1.NN>>Cn1ncnc1C1c2n[nH]c(=O)c3c2C(CCC3)NC1c1ccc(F)cc1,,CO,,O,O,test
US20160060267A1,N#Cc1cnn2c(=O)cc(-c3ccccc3)[nH]c12.O=C1CCC(=O)N1Br>>N#Cc1cnn2c(=O)c(Br)c(-c3ccccc3)[nH]c12,,CN(C)C=O,O,,,test
US20060173034A1,COc1cc2ncc(C(N)=O)c(Cl)c2cc1OC.Cc1c(N)cccc1C(=O)O>>COc1cc2ncc(C(N)=O)c(Nc3ccc(C(=O)O)cc3C)c2cc1OC,,CS(C)=O,,CC(=O)O,,test
US20010044539A1,C=CCBr.O=C1CCCCC1>>C=CCC1CCCCC1=O,,Cc1ccccc1,,CCOC(C)=O,CC(C)(C)[O-].[K+],test
US20130331452A1,CCOC(=O)c1ccc(F)c(OCc2c(C)cccc2C)c1>>Cc1cccc(C)c1COc1cc(C(=O)O)ccc1F,,CCO,,[Na+].[OH-],,test
US20080306086A1,COC(=O)C1CC(N)CN1C(=O)OC(C)(C)C.O=Cc1ccccc1>>COC(=O)C1CC(NCc2ccccc2)CN1C(=O)OC(C)(C)C,CC(=O)O,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US06008245,CI.CN(C1c2cc(OCc3ccccc3)ccc2OC(C)(C)C1O)S(C)(=O)=O>>COC1C(N(C)S(C)(=O)=O)c2cc(OCc3ccccc3)ccc2OC1(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20110105566A1,BrCCC1CCCCC1.Cn1nnnc1C(=NOCc1cccc(NC(=O)OC(C)(C)C)n1)c1ccccc1>>Cn1nnnc1C(=NOCc1cccc(N(CCC2CCCCC2)C(=O)OC(C)(C)C)n1)c1ccccc1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US05556854,COC(=O)C1CN(Cc2ccccc2)CCC1=O.N>>COC(=O)C1=C(N)CCN(Cc2ccccc2)C1,,CCO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20120302539A1,CC(C)(C)OC(=O)NC1CCNCC1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>CC(C)(C)OC(=O)NC1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100022761A1,COC(=O)CCCCC(=O)N(C)CCC(O)c1cc(OC)c(OC)cc1[N+](=O)[O-].O=C(n1ccnc1)n1ccnc1>>NC(=O)O.c1c[nH]cn1,,ClCCl,,,,test
US20090105244A1,COc1nc(Cl)c(C#N)c(C)c1Cl.O=C(CS)NC1CC1>>COc1nc2sc(C(=O)NC3CC3)c(N)c2c(C)c1Cl,,CO,,O,C[O-].[Na+],test
US20090054425A1,CC(=O)N1CCN(c2ccc(Nc3nc(Nc4ccc5cnn(C)c5c4)c4cc[nH]c4n3)cc2)CC1>>Cn1ncc2ccc(Nc3nc(Nc4ccc(N5CCNCC5)cc4)nc4[nH]ccc34)cc21,,C1COCCO1,,CC(=O)O,[K+].[OH-],test
US20040209865A1,BrCCCCBr.NCCc1ccc(Br)cc1>>Brc1ccc(CCN2CCCC2)cc1,,CC#N,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20090048295A1,CCc1cccc(CC)c1-c1ccc2c(n1)CCCC2O.O=S(Cl)Cl>>CCc1cccc(CC)c1-c1ccc2c(n1)CCCC2Cl,,ClCCl,,,,test
US20090325956A1,CCOC(=O)c1cccc(CBr)c1.Nc1ccccc1Cl>>CCOC(=O)c1cccc(CNc2ccccc2Cl)c1,,CC#N,,CC(C)NC(C)C,,test
US20030073849A1,CNC.O=CC1CC1c1ccc2cc[nH]c2c1>>CN(C)CC1CC1c1ccc2cc[nH]c2c1,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04734418,CCN1CCC(=O)CC1=O.COC([O-])[O-]>>CCN1CCC(=O)C(=COC)C1=O,,CC(=O)OC(C)=O,,,,test
US20070078129A1,CC(C)(Br)C(=O)Br.Cc1ccc(N)c(O)c1>>Cc1ccc2c(c1)OC(C)(C)C(=O)N2,,CC(Cl)Cl,,,,test
US06323309B1,CCCC[Sn](CCCC)(CCCC)c1scc2c1OCCO2.O=Cc1cc(Br)ccc1O>>O=Cc1cc(-c2scc3c2OCCO3)ccc1O,,CN(C)C=O,,,,test
US20050256308A1,Cl.Oc1ccc2c(c1)CCC21C=C(c2ccc(OCCN3CCCCC3)cc2)c2cc(O)ccc21>>Cl.Oc1ccc2c(c1)CCC21CC(c2ccc(OCCN3CCCCC3)cc2)c2cc(O)ccc21,[Pd],CC(=O)O,CCO,,,test
US20100168122A1,CCCCCn1c(=O)n(CCCC(=O)OCC)c(=O)c2[nH]c(Cl)nc21.N=C(Cc1ccsc1)NO>>CCCCCn1c(=O)n(CCCc2nc(Cc3ccsc3)no2)c(=O)c2[nH]c(Cl)nc21,,CCO,,C,C[O-].[Na+],test
US20080153828A1,BrBr.COC(=O)c1cccc2cc(C)oc12>>COC(=O)c1cccc2c(Br)c(C)oc12,,CCOC(C)=O,ClCCl,,,test
US04851413,COc1c(C)c(C)c(OC)c(C(CCCCCC(=O)O)c2cccnc2)c1C>>COc1c(C)c(C)c(OC)c(C(CCCCCCO)c2cccnc2)c1C,,O,,C1CCOC1,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20080015202A1,CC(=O)Nc1nc(CCc2ccc(CCCN)s2)cs1.CC(C)(C)OC(=O)N=C(NC(=O)OC(C)(C)C)n1cccn1>>CC(=O)Nc1nc(CCc2ccc(CCCNC(NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)s2)cs1,,C1CCOC1,,,,test
US20160024056A1,CS(=O)(=O)Cl.c1cc2c(ccn2CC2CCNCC2)cc1-c1cnn(C2CCCCO2)c1>>CS(=O)(=O)N1CCC(Cn2ccc3cc(-c4cnn(C5CCCCO5)c4)ccc32)CC1,,ClCCl,O,CCN(CC)CC,CO,test
US20120115811A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)Nc1cc(-c2ccncc2)no1.O=C(O)C(F)(F)F>>N[C@@H](Cc1ccc(Cl)cc1)C(=O)Nc1cc(-c2ccncc2)no1.O=C(O)C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080287453A1,CC(C)(C)OC(=O)N1CCN(c2nc3cc(Cl)ccc3[nH]2)CC1>>Clc1ccc2[nH]c(N3CCNCC3)nc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100261708A1,CC(C)(C)OC(=O)N1CCCN(c2nc3ccccc3[nH]2)CC1>>c1ccc2[nH]c(N3CCCNCC3)nc2c1,,CO,,Cl,,test
US20100160335A1,CCC(=O)Cl.COc1cccc2nc(C(F)(F)F)oc12>>CCC(=O)c1ccc(OC)c2oc(C(F)(F)F)nc12,Cl[Ti](Cl)(Cl)Cl,ClCCl,,Cl,,test
US20080274892A1,CC1CN(Cc2ccccc2[N+](=O)[O-])C(=S)O1>>CC1CN(Cc2ccccc2N)C(=S)O1,[Fe],CCO,O,[Cl-].[NH4+],,test
US04767768,CCC(=CC(C=O)=NO)C(C)[N+](=O)[O-]>>CCC(=CC(CO)=NO)C(C)[N+](=O)[O-],,CCO,,Cl,[BH4-].[Na+],test
US20100184815A1,CC(C)(C)OC(=O)C(C)(C)Oc1ccc(C(=O)O)cc1.COC(c1ccc(Cn2cc(CO)nn2)cc1)(C(F)(F)F)C(F)(F)F>>COC(c1ccc(Cn2cc(COC(=O)c3ccc(OC(C)(C)C(=O)OC(C)(C)C)cc3)nn2)cc1)(C(F)(F)F)C(F)(F)F,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05534518,C=C(C)CCl.Cc1cccc(O)c1[N+](=O)[O-]>>C=C(C)COc1cccc(C)c1[N+](=O)[O-],,CS(C)=O,O,[I-].[K+],,test
US20070299077A1,CC(=O)Cl.CCCCOc1ccc(C(=O)Nc2ccc(N3CCC(=O)C3)cc2)cc1.NCCO>>CCCCOc1ccc(C(=O)Nc2ccc(N3CCC4(C3)OCCN4C(C)=O)cc2)cc1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20090281073A1,Cc1cc(N)[nH]n1.Clc1nc(Cl)c2sccc2n1>>Cc1cc(Nc2nc(Cl)nc3ccsc23)[nH]n1,,CN1CCCC1=O,,CCN(CC)CC,O,test
US20090215778A1,COc1ccc(-c2nc3c(C(=O)O)cnn3c(C(F)(F)F)c2C)cc1.C[C@H]1CN([C@H](C)c2ccccc2)CCN1>>COc1ccc(-c2nc3c(C(=O)N4CCN([C@@H](C)c5ccccc5)C[C@H]4C)cnn3c(C(F)(F)F)c2C)cc1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080085890A1,CCN(CC)CCCCN.COC=C1C(=O)NC(=O)c2ccc(Br)cc21>>CCN(CC)CCCCN/C=C1\C(=O)NC(=O)c2ccc(Br)cc21,,CCOCC,,CN(C)C=O,,test
US20160016903A1,CN(C)C1(c2ccc(Cl)s2)CCC2(CC1)CC(=O)N(C(=O)OC(C)(C)C)C2>>CN(C)C1(c2ccc(Cl)s2)CCC2(CC1)CNC(=O)C2,,ClCCl,,O=C(O)C(F)(F)F,,test
US07851473B2,O=C(OCC(Cl)(Cl)Cl)N(C(=O)OCC(Cl)(Cl)Cl)c1noc2ccccc12.c1ccc(-c2csc(N3CCNCC3)c2)cc1>>O=C(Nc1noc2ccccc12)N1CCN(c2cc(-c3ccccc3)cs2)CC1,,O,,CCN(C(C)C)C(C)C,CS(C)=O,test
US05108486,CCN(CC)c1c(Cl)cc(NC(=S)N(C)N)cc1Cl.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCN(CC)c1c(Cl)cc(-n2c(C(F)(F)F)nn(C)c2=S)cc1Cl,,Cc1ccccc1,,,,test
US20030018067A1,CCCCC(=O)c1c(-c2ccc3c(Br)c(OC(Cc4ccccc4)C(=O)OCC)ccc3c2)oc2ccccc12>>CCCCC(=O)c1c(-c2ccc3c(Br)c(OC(Cc4ccccc4)C(=O)O)ccc3c2)oc2ccccc12,,C1CCOC1,O,[K+].[OH-],,test
US20160184305A1,CCI.COc1cc2ccnc(O)c2cc1Br>>CCn1ccc2cc(OC)c(Br)cc2c1=O,,C1COCCO1,CCOC(C)=O,O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20130102611A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1ccc(-c2nc3c(nc2-c2ccccc2)NCCC3)cc1>>CC(C)(C)OC(=O)N1CCCc2nc(-c3ccccc3)c(-c3ccccc3)nc21,CN(C)c1ccncc1,C1CCOC1,,O,,test
US20100010035A1,COCCOCN(c1noc(C)c1C)S(=O)(=O)c1sc(C)cc1-c1ccc(Cn2nc(-c3cccs3)c3c(C)nc(C)cc32)cc1COC>>COCc1cc(Cn2nc(-c3cccs3)c3c(C)nc(C)cc32)ccc1-c1cc(C)sc1S(=O)(=O)Nc1noc(C)c1C,,CCO,,Cl,,test
US20010020310A1,CC(C)(C)C(=O)CC(=O)C(C)(C)C.Nc1[nH]ncc1[N+](=O)[O-]>>CC(C)(C)c1cc(C(C)(C)C)n2ncc([N+](=O)[O-])c2n1,,CC(=O)O,,Cl,,test
US20110144105A1,COC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1F.Cc1ccc(S(=O)(=O)OC(=CC2CCCC2)c2cc3cc(C)cnc3n2S(=O)(=O)c2ccccc2)cc1>>COC(=O)c1ccc(C(=CC2CCCC2)c2cc3cc(C)cnc3n2S(=O)(=O)c2ccccc2)cc1F,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US20090163488A1,CC(C)(C)OC(=O)Nc1cc(O)ccc1F.O=[N+]([O-])c1ccc(Br)cn1>>CC(C)(C)OC(=O)Nc1cc(Oc2ccc([N+](=O)[O-])nc2)ccc1F,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US08895613B2,CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(=O)C(F)F)[C@@H](N/C(=N/C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)C1>>CCC(CC)O[C@@H]1C=C(C(=O)O)C[C@H](N/C(=N/C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)[C@H]1NC(=O)C(F)F,,C1COCCO1,,CC(=O)O,[Li+].[OH-],test
US20050080087A1,CCC(COCc1ccccc1)NC(=O)c1cnn(-c2ccc(Cl)cc2Cl)c1-c1cccc(Br)c1.OB(O)c1ccsc1>>CCC(COCc1ccccc1)NC(=O)c1cnn(-c2ccc(Cl)cc2Cl)c1-c1cccc(-c2cccs2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20090137561A1,CC1(C)CCC=C1c1cc(CO)ccc1-c1cc(C(F)(F)F)ccc1F.O=S(Cl)Cl>>CC1(C)CCC=C1c1cc(CCl)ccc1-c1cc(C(F)(F)F)ccc1F,,CN(C)C=O,ClCCl,,,test
US20090264445A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.OCC1(F)CCCC1>>O=S(=O)(OCC1(F)CCCC1)C(F)(F)F,,ClCCl,,CCN(CC)CC,Cl,test
US20100184741A1,CN(c1ccccn1)S(=O)(=O)c1cc(B2OC(C)(C)C(C)(C)O2)c(Cl)cc1OCCCCO.N#Cc1cc(C(F)(F)F)ncc1Br>>CN(c1ccccn1)S(=O)(=O)c1cc(-c2cnc(C(F)(F)F)cc2C#N)c(Cl)cc1OCCCCO,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20020193614A1,COc1ccc(CNC(=O)c2cc(C#N)ccc2N[C@@H]2CCN(C(=O)OC(C)(C)C)C2)cc1OC>>COc1ccc(CNC(=O)c2cc(C#N)ccc2N[C@@H]2CCNC2)cc1OC,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20060041123A1,COc1c(F)ccc2[nH]ccc(=O)c12.O=C1CCC(=O)N1Cl>>COc1c(F)ccc2[nH]cc(Cl)c(=O)c12,,CC(=O)O,,,,test
US07374583B2,CC(=O)O.CCn1cc(N)c(O)n1.COc1ccc(C=CC(=O)c2ccccn2)cc1>>CC(=O)[O-].CCn1ncc(/N=C2\C=C(c3ccc(OC)cc3)[n+]3ccccc32)c1O,,CC(=O)O,,O,O=S(=O)(O)O,test
US20020160931A1,CC(=O)Cl.CC1=CC(C)(C)c2ccccc21>>CC(=O)C1=C(C)c2ccccc2C1(C)C,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20040209929A1,CC(C)OC(=O)CN=NCC(=O)OC(C)C.Cc1oc(-c2ccccc2)nc1CCO.Nc1c(O)cccc1[N+](=O)[O-]>>Cc1oc(-c2ccccc2)cc1CCOc1cccc([N+](=O)[O-])c1N,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20080207611A1,c1cc(-c2nc(N3CCOCC3)c3sc(CN4CCNCC4)cc3n2)c2cn[nH]c2c1.c1ccc(OCC2CO2)cc1>>OC(COc1ccccc1)CN1CCN(Cc2cc3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3s2)CC1,,CN(C)C=O,ClCCl,,,test
US20020161231A1,O=C(O)[C@H]1Cc2ccccc2CN1.O=S(=O)(Cl)c1ccc(-c2ccccc2)cc1>>O=C(O)[C@H]1Cc2ccccc2CN1S(=O)(=O)c1ccc(-c2ccccc2)cc1,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20100184794A1,Cc1sc(C=O)cc1Br.OCCO>>Cc1sc(C2OCCO2)cc1Br,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080064712A1,O=C1CC[C@@]2(OCCCc3ccccc3)[C@H]3Cc4cccc5c4[C@@]2(CCN3CC2CC2)[C@H]1O5>>O=C1CC[C@@]2(OCCCc3ccccc3)[C@H]3Cc4cccc(O)c4[C@@]2(CCN3CC2CC2)C1,[Zn],CO,,Cl,[Cl-].[NH4+],test
US20090131399A1,NCC1CCCO1.O=S(=O)(Cl)c1ccc(Br)cc1>>O=S(=O)(NCC1CCCO1)c1ccc(Br)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160096839A1,C=CC[C@H](NC(=O)OC(C)(C)C)c1cccc(-c2c([N+](=O)[O-])cnn2C(F)F)c1>>C=CC[C@H](NC(=O)OC(C)(C)C)c1cccc(-c2c(N)cnn2C(F)F)c1,[Zn],CC(C)=O,O,[Cl-].[NH4+],,test
US20050222152A1,N#Cc1nc(Nc2ccc(Cl)cc2)c([N+](=O)[O-])c(N2CCOCC2)n1>>N#Cc1nc(Nc2ccc(Cl)cc2)c(N)c(N2CCOCC2)n1,[Pd],CCOC(C)=O,,,,test
US04925859,CC(C(=O)O)=C(NC(=O)C(F)(F)F)c1ccccc1>>Cc1c(-c2ccccc2)nc(C(F)(F)F)oc1=O,,CC(=O)OC(C)=O,,O,,test
US20040176367A1,CCCCc1nc2cnc3ccccc3c2n1NCc1ccccc1.O=C(OO)c1cccc(Cl)c1>>CCCCc1nc2c[n+]([O-])c3ccccc3c2n1NCc1ccccc1,,ClCCl,,,,test
US20060100246A1,COC(=O)C1CN(C(=O)OC(C)(C)C)CCC1O>>COC(=O)C1=CCCN(C(=O)OC(C)(C)C)C1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US06521754B2,COc1ccc(-c2csc(NC(c3ccccc3)(c3ccccc3)c3ccccc3)n2)c2sc(NC(=O)O)nc12>>COc1ccc(-c2csc(N)n2)c2sc(NC(=O)O)nc12,,CO,Cl,O=C([O-])O.[Na+],,test
US20030032671A1,Cc1cc(C)c(NC(=O)CN(Cc2ccc(SC(C)(C)C(=O)OC(C)(C)C)cc2)Cc2ccco2)c(C)c1>>Cc1cc(C)c(NC(=O)CN(Cc2ccc(SC(C)(C)C(=O)O)cc2)Cc2ccco2)c(C)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080139639A1,CN(Cc1cc(-c2ccccc2)n(S(=O)(=O)c2ccc(Cl)nc2)c1)C(=O)OC(C)(C)C>>CNCc1cc(-c2ccccc2)n(S(=O)(=O)c2ccc(O)nc2)c1.Cl,,C1CCOC1,,O,[Na+].[OH-],test
US04710507,C=C1CC(=O)O1.Cc1cc(Br)ccc1N>>CC(=O)CC(=O)Nc1ccc(Br)cc1C,,Cc1ccccc1,,,,test
US05786356,CC(C)(C)[Si](C)(C)Cl.Nc1cccc(OC[C@@H](O)CN(Cc2ccccc2)Cc2ccccc2)c1N.c1c[nH]cn1>>CC(C)(C)[Si](C)(C)O[C@H](COc1cccc2nc[nH]c12)CN(Cc1ccccc1)Cc1ccccc1,,CN(C)C=O,,,,test
US20080261921A1,CCOC(=O)C(=O)N(C)C.Fc1ccc(Br)cn1>>CN(C)C(=O)C(=O)c1cc(Br)cnc1F,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20070060577A1,CCN.CCOC(=O)c1cn(C2CC3CCC2C3)c2nc(Nc3ccc(N4CCN(C)CC4)cc3)ncc2c1=O>>CCNC(=O)c1cn(C2CC3CCC2C3)c2nc(Nc3ccc(N4CCN(C)CC4)cc3)ncc2c1=O,,CO,,,,test
US20100240656A1,CC(=O)Cl.CC(C)N(CCCn1c(Sc2nc3cccc(Cl)c3s2)nc(C(N)=O)c1N)C(=O)OC(C)(C)C>>CC(=O)Nc1c(C(N)=O)nc(Sc2nc3cccc(Cl)c3s2)n1CCCN(C(=O)OC(C)(C)C)C(C)C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160137637A1,Nc1ncns1.O=C(O)c1csc(-c2ccc3c(c2)CCO3)n1>>O=C(Nc1ncns1)c1csc(-c2ccc3c(c2)CCO3)n1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040242890A1,CCOC(=O)NN.O=C=Nc1cccc(I)c1>>CCOC(=O)NNC(=O)Nc1cccc(I)c1,,ClCCl,,CCO,,test
US20090163552A1,CCOC(=O)C(C1CCCCC1)n1c(-c2ccc(Cl)cc2)nc2cc(F)c(F)cc21>>O=C(O)C(C1CCCCC1)n1c(-c2ccc(Cl)cc2)nc2cc(F)c(F)cc21,,C1COCCO1,O,[Li+].[OH-],,test
US20020169166A1,CC(C)COC(=O)Cl.c1ccc(N2CCN(Cc3nc4ccccc4[nH]3)CC2)nc1>>CC(C)COC(=O)n1c(CN2CCN(c3ccccn3)CC2)nc2ccccc21,,ClCCl,,,,test
US20140061538A1,BrC(Br)(Br)Br.CCCCC(C=O)CC>>CCCCC(C=C(Br)Br)CC,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070185160A1,Cc1ccc(Cl)cc1C(=O)N(C)C.N#Cc1ccccc1N1CCOCC1>>O=c1[nH]c(-c2ccccc2N2CCOCC2)cc2ccc(Cl)cc12,,C1CCOC1,,[Cl-].[NH4+],,test
US20100179216A1,O=C1CCC(=O)N1Br.O=[N+]([O-])c1cccc(CCCO)c1>>O=[N+]([O-])c1cccc(CCCBr)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100190775A1,CSc1ncc2c(n1)N1CCC[C@H]1CN(c1cccc(C(N)=NO)c1)C2=O.S=C(n1ccnc1)n1ccnc1>>CSc1ncc2c(n1)N1CCC[C@H]1CN(c1cccc(-c3nsc(=O)[nH]3)c1)C2=O,,CCOC(C)=O,,C1CCOC1,,test
US20110177950A1,CC(C)(C)C(=O)Cn1cncn1.Fc1ccc(/C=C/CCBr)cc1>>CC(C)(C)C(=O)C(CC/C=C/c1ccc(F)cc1)n1cncn1,,CC#N,,[K+].[OH-],,test
US20140315886A1,CCCC[Sn](CCCC)(CCCC)c1cscn1.Fc1ccc(-c2ccc3nc(-c4cccnc4)nc(Br)c3c2)c(F)c1>>Fc1ccc(-c2ccc3nc(-c4cccnc4)nc(-c4cscn4)c3c2)c(F)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,,,test
US20140171403A1,Cc1cc(C(=O)O)cc(C(F)(F)F)c1>>Cc1cc(CO)cc(C(F)(F)F)c1,,C1CCOC1,,,,test
US20020091131A1,CC(=O)OC(C)=O.CCOC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](CC(C)C)[C@H](O)c1ccccc1>>CCOC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](CC(C)C)[C@H](OC(C)=O)c1ccccc1,,c1ccncc1,,,,test
US20090066245A1,Cc1ccc(-c2ccc3ccc4c(-c5ccc(C)cc5)ccc5ccc2c3c54)cc1.O=C1CCC(=O)N1Br>>Cc1ccc(-c2ccc3ccc4c(-c5ccc(C)cc5)cc(Br)c5ccc2c3c54)cc1,,O,,CN(C)C=O,,test
US20110059941A1,CN(C)C=O.O=C(O)c1cnc(Cl)c(Cl)c1>>CN(C)C(=O)c1cnc(Cl)c(Cl)c1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20120295884A1,CC(=O)Cl.O=C(Nc1cccc(OC(F)(F)F)c1)[C@@H]1CCCN1C(=O)Cc1c[nH]c2ccccc12>>CC(=O)n1cc(CC(=O)N2CCC[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2)c2ccccc21,CN(C)c1ccncc1,CN(C)C=O,,O=C(O)CC(O)(CC(=O)O)C(=O)O,,test
US04062973,CC(Cl)c1ccc(C2CCCCC2)c(Cl)c1>>CC(Cl)c1ccc(C2CCCCC2)cc1,,C1CCCCC1,CCOC(C)=O,,,test
US20100286123A1,CCOC(=O)C(OCC)OCC.OCCc1ccccc1Br>>COC(=O)C1OCCc2c(Br)cccc21,Cl[Ti](Cl)(Cl)Cl,C[N+](=O)[O-],,,,test
US05661150,COc1cc2c(CO)nn(Cc3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)c2cc1OC.O=S(Cl)Cl>>COc1cc2c(CCl)nn(Cc3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)c2cc1OC,,ClCCl,,O=C([O-])O.[Na+],,test
US20150166564A1,C[N+](=O)[O-].O=Cc1nccs1>>O=[N+]([O-])/C=C/c1nccs1,CN(C)c1ccncc1,CC#N,,CC(=O)OC(C)=O,,test
US20140066432A1,CCOC(=O)C1=Cc2cc(Br)ccc2N=C(N)C1.CN(C)S(=O)(=O)c1ccc(B(O)O)cc1>>CCOC(=O)C1=Cc2cc(-c3ccc(S(=O)(=O)N(C)C)cc3)ccc2N=C(N)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04171375,C1=COCCC1.COC(=O)CCCCCCC1=CCC(O)C1=O>>COC(=O)CCCCCCC1=CCC(OC2CCCCO2)C1=O,Cc1ccc(S(=O)(=O)O)cc1,ClCCl,,c1ccncc1,,test
US20080280950A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(OCc3ccccc3)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(O)CC1,[Pd],CCO,,,,test
US05510360,Cc1oc(-c2ccc(C(F)(F)F)cc2)[n+]([O-])c1C.Cl>>Cc1oc(-c2ccc(C(F)(F)F)cc2)nc1CCl,,ClC(Cl)Cl,,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US05328637,CCCCCc1ccc(-c2ccc(-c3ccc(C(Br)C(C)Br)c(F)c3F)cc2)cc1>>CC#Cc1ccc(-c2ccc(-c3ccc(CCCCC)cc3)cc2)c(F)c1F,,COC(C)(C)C,,O,,test
US04607030,N.O=C(CCl)NCc1cc2c(c(S(=O)(=O)Cl)c1O)CCC2>>NS(=O)(=O)c1c(O)c(CNC(=O)CCl)cc2c1CCC2,,CC(C)=O,O,,,test
US20160264518A1,OCc1nc(Cl)c(Cl)[nH]1>>O=Cc1nc(Cl)c(Cl)[nH]1,O=[Mn]=O,CC#N,,,,test
US20110207715A1,CCCC[Sn](CCCC)(CCCC)c1nccs1.Cc1ccc(I)c(C(=O)N2CC(COc3ccc(F)c(C)c3)CCCC2C)c1>>Cc1ccc(-c2nccs2)c(C(=O)N2CC(COc3ccc(F)c(C)c3)CCCC2C)c1,,Cc1ccccc1,,,,test
US04769366,COc1ccc(C2=CC(N3CCN(Cc4ccccc4)CC3)=NC23C=CC(=O)C=C3)cc1>>O=C1C=CC2(C=C1)N=C(N1CCN(Cc3ccccc3)CC1)C=C2c1ccc(O)cc1,,CC(=O)O,ClC(Cl)Cl,Br,,test
US20100041696A1,CC(C)(C)OC(=O)N1CCc2cc(NC(=O)c3cnn(Cc4ccc(Cl)c(Cl)c4)c3)ccc2C1.Cl>>Cl.O=C(Nc1ccc2c(c1)CCNC2)c1cnn(Cc2ccc(Cl)c(Cl)c2)c1,,CCOC(C)=O,,,,test
US20150376134A1,CC(C)(C)c1cc(C(C)(C)C)c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O.CN(C)C=O>>CC(C)(C)c1cc(C(C)(C)C)c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O.CN(C)C=O,,CCOC(C)=O,,CCN(C(C)C)C(C)C,,test
US20040072843A1,O=c1n(CCCC2CCCC2)ccn1-c1ccc([N+](=O)[O-])cc1>>Nc1ccc(N2CCN(CCCC3CCCC3)C2=O)cc1,[Pd],CCOC(C)=O,,,,test
US20100305145A1,CCOC(=O)[C@H](C)C[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)c1cnc(OC)s1>>CCOC(=O)[C@H](C)C[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)c1c[nH]c(=O)s1,,C1COCCO1,,Cl,,test
US20030149054A1,CN(CCOc1ccc(C=O)cc1)c1nc2ccccc2o1.O=C1CSC(=O)N1>>CN(CCOc1ccc(C=C2SC(=O)NC2=O)cc1)c1nc2ccccc2o1,,Cc1ccccc1,,C1CC[NH2+]CC1.CC(=O)[O-],,test
US20100010014A1,Fc1ccc(SC(=S)Sc2ccc(F)cc2)cc1.N#CCC(=O)c1ccc(F)cc1>>N#CC(C(=O)c1ccc(F)cc1)C(=S)Sc1ccc(F)cc1,,c1ccccc1,,CN(C)C=O,[H-].[Na+],test
US20070066583A1,COc1cc(N2CCN(C(=O)Cn3c(=O)oc4cc(O)ccc43)CC2)ccc1Cl.OCCOC1CCCCO1>>COc1cc(N2CCN(C(=O)Cn3c(=O)oc4cc(OCCOC5CCCCO5)ccc43)CC2)ccc1Cl,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140213586A1,CCOC(=O)Cl.O=Cc1c[nH]c2ccccc12>>CCOC(=O)n1cc(C=O)c2ccccc21,,CS(C)=O,,[H-].[Na+],,test
US20100298336A1,O=Cc1cncc(F)c1>>OCc1cncc(F)c1,,CO,,[BH4-].[Na+],[Cl-].[NH4+],test
US20120115850A1,CC(Nc1cc(N2CCNCC2)ccc1S(C)(=O)=O)c1cc(Cl)cc2c1OCO2.Cl>>CC(Nc1cc(N2CCNCC2)ccc1S(C)(=O)=O)c1cc(Cl)cc2c1OCO2.Cl,,CCOCC,ClCCl,,,test
US20050277619A1,COC(=O)c1nc2c(N)ncnc2n1CCc1ccccc1>>Nc1ncnc2c1nc(CO)n2CCc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20050197340A1,C[C@H](O)CN.Fc1ccc(Oc2nc3[nH]nc(-c4ccccc4Cl)c3nc2Cl)c(F)c1>>C[C@@H](O)CNc1nc2c(-c3ccccc3Cl)n[nH]c2nc1Oc1ccc(F)cc1F,,CCO,,,,test
US20140107194A1,CC[C@H](C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O.O=C(O)c1ccc(C[C@@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@H]2O)cc1>>CC[C@H](C)[C@H](N)C(=O)O[C@@H]1c2ccccc2C[C@@]1(Cc1ccc(C(=O)O)cc1)C1=Cc2ccccc2C1,CN(C)c1ccncc1,CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20090105307A1,COc1ccc(CN(C[C@H]2COC(N)=N2)c2cccc(Cl)c2)cc1>>NC1=N[C@@H](CNc2cccc(Cl)c2)CO1,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US06100258,C=C(C)COc1ccc(Cl)cc1CNCC.NS(=O)(=O)c1ccc(Cl)nn1>>C=C(C)COc1ccc(Cl)cc1CN(CC)c1ccc(S(N)(=O)=O)nn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20020137766A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN(CCCNc1ccc(C#N)cc1)C1C2CCC1CNC2>>CN(CCCNc1ccc(C#N)cc1)C1C2CCC1CN(C(=O)OC(C)(C)C)C2,,ClCCl,,,,test
US20020091261A1,Cl.Clc1nnc(Cc2ccncc2)c2ccccc12.Nc1ccc(Cl)cc1>>Cl.Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1,,CCO,,,,test
US04269788,CC(COS(C)(=O)=O)C1(c2ccccc2)C=CCC=C1.CCNCC>>CCN(CC)CC(C)C1(c2ccccc2)C=CCC=C1,,Cc1ccccc1,,,,test
US20050282858A1,C#Cc1ccc(C2(C#N)CC2)cc1.CCN(CC)CC.CCOC(C)=O.O=C1CCC(=O)N1Cl>>Cc1nocc1-c1ccc(C2(C#N)CC2)cc1,,CCOC(C)=O,,C1CCOC1,,test
US20040204584A1,COC(=O)Nc1nc2c(OC)ccc(C3=COCCO3)c2s1>>COC(=O)Nc1nc2c(OC)ccc(C3COCCO3)c2s1,[Pd],C1COCCO1,CC(=O)O,[H][H],,test
US20150239908A1,CC(C)=C[C@H]1C[C@H]2CSC(NC(=O)c3ccccc3)=N[C@@]2(c2ccc(F)cc2F)CO1>>CC(C)C[C@H]1C[C@H]2CSC(NC(=O)c3ccccc3)=N[C@@]2(c2ccc(F)cc2F)CO1,[Pd],CO,,[H][H],,test
US20080306045A1,CC(C)(C)OC(=O)N1CCCc2cc(N3CC[C@H](NS(=O)(=O)/C=C/c4ccc(Cl)s4)C3=O)ccc2C1.CI>>CN([C@H]1CCN(c2ccc3c(c2)CCCN(C(=O)OC(C)(C)C)C3)C1=O)S(=O)(=O)/C=C/c1ccc(Cl)s1,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20130079306A1,CCn1ncc2cc(CO)ccc21>>CCn1ncc2cc(C=O)ccc21,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04550105,COC(=O)/C(=N\O)c1csc(N)n1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)/C(=N\O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,CN(C)C=O,,CCN(CC)CC,O,test
US04600025,Cc1ncc(C(=O)N2CCCC2)s1>>Cc1ncc(CN2CCCC2)s1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100267697A1,CCOC(=O)c1ccc(N(CC)C2CC2)nc1.Nc1ccc(F)cc1>>CCN(c1ccc(C(=O)Nc2ccc(F)cc2)cn1)C1CC1,,Cc1ccccc1,,C[Al](C)C,,test
US20030220341A1,C=COC(=O)OCC1CCN(C(=O)OC=C)C1.Cl>>C=COC(=O)OCC1CCNC1.Cl,,ClCCl,,,,test
US20150266874A1,CCOC(=O)c1c[nH]nc1I.C[Si](C)(C)CCOCCl>>CCOC(=O)c1cn(COCC[Si](C)(C)C)nc1I,,C1CCOC1,,[H-].[Na+],,test
US20050065204A1,CCOC(=O)C1CC(=O)N(c2ccc(O)cc2)C1>>COC(=O)C1CC(=O)N(c2ccc(O)cc2)C1,,CCO,,,,test
US20080255111A1,CCOC(=O)C(=O)OCC.Cc1ccc(F)cc1[N+](=O)[O-]>>CCOC(=O)C(=O)Cc1ccc(F)cc1[N+](=O)[O-],,C1CCOC1,,O,[H-].[Na+],test
US20110065699A1,O=C1CCCc2c1cccc2-c1ccc2nc(-c3ccc(Cl)cc3)cn2c1>>OC1CCCc2c(-c3ccc4nc(-c5ccc(Cl)cc5)cn4c3)cccc21,,CO,,[BH4-].[Na+],,test
US20050054639A1,Nc1ccccc1Cl.O=C(O)CSc1nnnn1-c1cccc2ccccc12>>O=C(CSc1nnnn1-c1cccc2ccccc12)Nc1ccccc1Cl,,c1ccncc1,,O=P(Cl)(Cl)Cl,,test
US06159967,CC(C)(C)OC(=O)N1CCC2(CC1)SCc1ccccc12.Cl>>Cl.c1ccc2c(c1)CSC21CCNCC1,,C1COCCO1,ClCCl,,,test
US05227544,CC(C)C=O.CCCC=O>>CCC(C=O)=CC(C)C,,O,,,,test
US20080027059A1,Cc1ccc(C)n1-c1ccc(C(=O)CC(=O)C(F)(F)F)cc1.NO>>Nc1ccc(C2=NOC(O)(C(F)(F)F)C2)cc1,,CCO,O,Cl,[Na+].[OH-],test
US20140235643A1,CC(=O)c1nc2cccc(C)c2nc1-c1ccccc1>>Cc1cccc2nc(C(C)O)c(-c3ccccc3)nc12,,CO,,[BH4-].[Na+],,test
US05747498,COc1cc2ncnc(Cl)c2cc1OC.Cl.[N-]=[N+]=Nc1ccc(N)cc1>>COc1cc2ncnc(Nc3ccc(N=[N+]=[N-])cc3)c2cc1OC.Cl,,CC(C)O,,,,test
US20110212945A1,O=P(Cl)(Cl)Cl.O=[N+]([O-])c1cnc(O)c(I)c1>>O=[N+]([O-])c1cnc(Cl)c(I)c1,,O,,ClP(Cl)(Cl)(Cl)Cl,,test
US20140206681A1,COC(=O)[C@H]1CC[C@H](CO)N(C(=O)OCc2ccccc2)C1>>COC(=O)[C@H]1CC[C@@H](CO)N(C(=O)OCc2ccccc2)C1,,CO,,O=C=O,,test
US20040157804A1,O=C1c2c(c(OS(=O)(=O)C(F)(F)F)c3cccnc3c2OC(c2ccccc2)c2ccccc2)CN1Cc1ccc(F)cc1>>O=C1c2c(c(OS(=O)(=O)C(F)(F)F)c3cccnc3c2O)CN1Cc1ccc(F)cc1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20130158025A1,Cc1nn2c(-c3cccc(Cl)c3)cc(Cl)nc2c1I.OC[C@@H]1CCCN1>>Cc1nn2c(-c3cccc(Cl)c3)cc(N3CCC[C@H]3CO)nc2c1I,,CC#N,,CCN(C(C)C)C(C)C,,test
US09108973B2,C#Cc1cc(OC)cc(OC)c1.CC(C)(C)OC(=O)N1C[C@@H](n2nc(I)c3c(N)ncnc32)C[C@H]1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>COc1cc(C#Cc2nn([C@H]3C[C@@H](CO[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)N(C(=O)OC(C)(C)C)C3)c3ncnc(N)c23)cc(OC)c1,[Cu]I,C1CCOC1,O,CCN(CC)CC,CCOC(C)=O,test
US20090215778A1,CC(c1ccccc1)N1CCNCC1.COc1ccc(-c2cc(C(F)(F)F)n3ncc(C(=O)O)c3n2)cc1>>COc1ccc(-c2cc(C(F)(F)F)n3ncc(C(=O)N4CCN(Cc5ccccc5)CC4)c3n2)cc1,,CN(C)C=O,,O=C(Cl)C(=O)Cl,,test
US04518685,CNC(=O)NC.O=C(O)CC(=O)O>>CN1C(=O)CC(=O)N(C)C1=O,,CC(=O)O,,CC(=O)OC(C)=O,,test
US05232922,Cn1cnc(S(=O)(=O)Cl)c1.NCCc1ccc(OCC(=O)O)cc1>>Cn1cnc(S(=O)(=O)NCCc2ccc(OCC(=O)O)cc2)c1,,O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20110070595A1,CCn1c(-c2nonc2N)nc2c(Cl)ncc(OCC3CCN(C(=O)OC(C)(C)C)CC3)c21>>CCn1c(-c2nonc2N)nc2c(Cl)ncc(OCC3CCNCC3)c21.O=CO,,C1COCCO1,CO,Cl,,test
US20100113462A1,CC(C)Br.COC(=O)C1(NC(=O)c2cccc(C)c2O)CCSCC1>>COC(=O)C1(NC(=O)c2cccc(C)c2OC(C)C)CCSCC1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040102450A1,CSCC[C@H]1C(=O)N(Cc2ccc(C#N)c(N=C(c3ccccc3)c3ccccc3)c2)CCN1C(=O)OCc1ccccc1.c1ncncn1>>CSCC[C@@H]1NCCN(Cc2ccc3c(N)ncnc3c2)C1=O,,CCO,,CC(=O)O,,test
US20060194859A1,CC(C)(C)OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(Br)cc1.COC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(-c2ccc(Nc3nc4ccc(OC(F)(F)F)cc4s3)c(F)c2)cc1.Fc1ccc2nc(Nc3ccc(Br)cc3F)sc2c1>>CC(C)(C)OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(-c2ccc(Nc3nc4ccc(F)cc4s3)c(F)c2)cc1.O=C(c1ccc(-c2ccc(Nc3nc4ccc(F)cc4s3)c(F)c2)cc1)[C@@H]1CCC[C@H]1C(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US05631280,COC(=O)c1cccc(I)c1.O=[N+]([O-])c1cccc(O)c1>>COC(=O)c1cccc(Oc2cccc([N+](=O)[O-])c2)c1,[Cu],O,c1ccncc1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US04160032,O=C(O)Cc1cc(F)ccc1[N+](=O)[O-]>>O=C1Cc2cc(F)ccc2N1,O=[Pt],,,[H][H],,test
US20090181942A1,CCOC(=O)[C@H]1CCCN(C(=O)C[C@@H]2O[C@@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3c2nnc3C(F)(F)Cl)C1>>COc1cccc([C@@H]2O[C@@H](CC(=O)N3CCC[C@H](C(=O)O)C3)c3nnc(C(F)(F)Cl)n3-c3ccc(Cl)cc32)c1OC,,C1COCCO1,CCOC(C)=O,Cl,,test
US20110136792A1,CCOC(=O)[C@@H]1CCC(=O)N1Cc1cccc(COc2ccc(-c3cc(F)c(F)cc3OC)cc2)c1>>COc1cc(F)c(F)cc1-c1ccc(OCc2cccc(CN3C(=O)CC[C@H]3C(=O)O)c2)cc1,,C1CCOC1,,CO,[Li+].[OH-],test
US20070208046A1,Clc1ccnc(Cl)n1.OCc1ccc(F)cc1>>Fc1ccc(COc2ccnc(Cl)n2)cc1,,O,,C1CCOC1,[Li]CCCC,test
US20030083238A1,CS(=O)(=O)Cl.C[C@H]1CC[C@H](O)CC1>>C[C@@H]1CC[C@@H](OS(C)(=O)=O)CC1,,CCOC(C)=O,O,CCN(CC)CC,Cl,test
US20060281771A1,CC#N.COc1cc2ncnc(Cl)c2cc1OC.ClC(Cl)Cl.O=C(Nc1ccc(OC2CCCC2)cc1)Oc1ccc([N+](=O)[O-])cc1.O=C([O-])N(c1ccccc1)[N+](=O)[O-]>>COc1cc2ncnc(N3CCC(NC(=O)Nc4ccc(OC5CCCC5)cc4)C3)c2cc1OC,,ClC(Cl)Cl,,,,test
US20070197621A1,CCc1cc(OC)cc(CC)c1C=O>>CCc1cc(O)cc(CC)c1C=O,,ClCCl,,BrB(Br)Br,,test
US20070049620A1,CCOC(CBr)OCC.N#CCc1ccc(Br)cc1>>CCOC(CC(C#N)c1ccc(Br)cc1)OCC,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20070129372A1,COC(=O)c1ccc(OC)c(-c2c(=O)ccn3nc(Cl)ccc23)c1.Oc1ccc(F)cc1F>>COC(=O)c1ccc(OC)c(-c2c(=O)ccn3nc(Oc4ccc(F)cc4F)ccc23)c1,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050234244A1,COc1ccc(NN)cc1Cl.O=C(Cl)c1ccc(F)cc1.c1ccncc1>>CC=NN(C(=O)c1ccc(F)cc1)c1ccc(OC)cc1,,CCOCC,,,,test
US20050192302A1,CC(=O)OC(C)=O.Cc1cc(C(F)(F)F)cc[n+]1[O-]>>CC(=O)OCc1cc(C(F)(F)F)ccn1,,CCO,,O=C([O-])O.[Na+],,test
US20090023725A1,Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc2[nH]ncc2c1.FC(F)(F)c1ccc(CBr)cc1>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc2c(cnn2Cc2ccc(C(F)(F)F)cc2)c1,,CN(C)C=O,,[H-].[Na+],,test
US06046213,CC(C(=O)c1ccc(O[Si](C(C)C)(C(C)C)C(C)C)c(F)c1)N1CCC(O)(c2ccc(C(F)(F)F)cc2)CC1>>CC(C)[Si](Oc1ccc([C@@H](O)[C@@H](C)N2CCC(O)(c3ccc(C(F)(F)F)cc3)CC2)cc1F)(C(C)C)C(C)C,,CCO,,[BH4-].[Na+],,test
US20110046127A1,Cc1nc2ccc(Cl)nn2c1[N+](=O)[O-].NCc1ccc(Cl)c(Cl)c1>>Cc1nc2ccc(NCc3ccc(Cl)c(Cl)c3)nn2c1[N+](=O)[O-],,C1COCCO1,,,,test
US20160096827A1,N#Cc1cc(-c2ncnc(Cl)n2)ccc1OC1CCOCC1.Nc1ccc(Cn2ccnc2)cc1>>N#Cc1cc(-c2ncnc(Nc3ccc(Cn4ccnc4)cc3)n2)ccc1OC1CCOCC1,,CC#N,,CN(C)C=O,,test
US20040048908A1,COC(=O)CCc1cnoc1-c1ccc(Cl)c(F)c1>>OCCCc1cnoc1-c1ccc(Cl)c(F)c1,,C1CCOC1,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US04626535,C/C=C(\C(=O)O)c1nsc(NC(=O)OC(C)(C)C)n1>>C/C=C(\C(=O)O)c1nsc(N)n1,,O=C(O)C(F)(F)F,,,,test
US07319104B2,Brc1ccc(Br)nc1.CCOC(=O)C(C)(C)Oc1ccc(CCNCc2ccc(C(F)(F)F)cc2)cc1>>CCOC(=O)C(C)(C)Oc1ccc(CCN(Cc2ccc(C(F)(F)F)cc2)c2ccc(Br)cn2)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20150158855A1,CCOC(=O)C(Cc1cc(I)ccc1F)(NC(=O)OC(C)(C)C)C(=O)OCC>>CC(C)(C)OC(=O)NC(Cc1cc(I)ccc1F)C(=O)O,,CCO,,O,[Na+].[OH-],test
US06245761B1,CC(C)(C)OC(=O)N1CCC(C)(C)C1=O>>CC(C)(CO)CCNC(=O)OC(C)(C)C,,CCO,,[BH4-].[Na+],,test
US20110082210A1,CC(C)(C)OC(=O)NCCOCCN.CC(C)(Oc1ccc(C(=O)c2ccc(Cl)cc2)cc1)C(=O)O>>CC(C)(C)OC(=O)NCCOCCNC(=O)C(C)(C)Oc1ccc(C(=O)c2ccc(Cl)cc2)cc1,,ClCCl,,CCN=C=NCCCN(C)C,,test
US04963553,FC(F)(F)c1cccc(-c2ccnc3c(Cl)cnn23)c1>>FC(F)(F)c1cccc(C2=CCNc3c(Cl)cnn32)c1,,CC(=O)O,,[BH3-]C#N.[Na+],,test
US20040058918A1,O=C1NNC(c2ccncc2)C1c1ccc(Cl)c(Cl)c1.O=Cc1cccnc1>>O=C1NN(Cc2cccnc2)C(c2ccncc2)C1c1ccc(Cl)c(Cl)c1,,ClC(Cl)Cl,,,,test
US05910506,C=CCn1c(COCc2ccccc2)nc(C(C)C)c1Sc1cccc(Cl)c1.ClB(Cl)Cl>>C=CCn1c(CCl)nc(C(C)C)c1Sc1cccc(Cl)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20030186348A1,CC1=Nc2ccc(CC(=O)O)cc2C1(C)C.O=[N+]([O-])c1cc(CCl)cc([N+](=O)[O-])c1.[Br-]>>O=C(O)Cc1ccc2c(c1)CC=[N+]2Cc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1.[Br-],,O=S1(=O)CCCC1,,CCOC(C)=O,,test
US20100063054A1,CCn1cc(-c2ccc(Cl)nc2)ccc1=O.NN>>CCn1cc(-c2ccc(NN)nc2)ccc1=O,,CC(C)O,O,CO,,test
US20150031679A1,CC1CCCN1.COC(=O)c1ccc2nc(-c3ccccc3)c(Br)nc2c1>>COC(=O)c1ccc2nc(-c3ccccc3)c(N3CCCC3C)nc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140302523A1,CC(C)(C)OC(=O)NCCOCCOCCOCCn1cc(CCC(=O)NCCOCCOCCOCC(=O)NCCOCCOCCCCCCCl)nn1>>NCCOCCOCCOCCn1cc(CCC(=O)NCCOCCOCCOCC(=O)NCCOCCOCCCCCCCl)nn1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20070259849A1,C1COCCN1.COC(=S)c1cnc(C)nc1C.O=C(OO)c1cccc(Cl)c1>>COC(=O)c1cnc(N2CCOCC2)nc1C,,ClCCl,,,,test
US20150018422A1,C=O.CCOC(=O)CC(c1cccc(CNc2ccc(-c3cc(OC)ccc3F)c(CC(C)(C)C)c2)c1)C1CC1>>CCOC(=O)CC(c1cccc(CN(C)c2ccc(-c3cc(OC)ccc3F)c(CC(C)(C)C)c2)c1)C1CC1,,CC#N,CC(=O)O,O=C([O-])O.[Na+],,test
US20110183954A1,COCn1cnc([N+](=O)[O-])c1.Clc1nc(Cl)nc(Cl)n1>>COCn1cnc(Nc2nc(Cl)nc(Cl)n2)c1,[Pd],CCO,,[H][H],,test
US20150322075A1,CCOC(=O)CBr.O=c1nc(Cl)cc2n1CCCN2.OCc1ccc(F)c(F)c1>>O=C(O)CN1CCCn2c1cc(OCc1ccc(F)c(F)c1)nc2=O,,C1CCOC1,,[H-].[Na+],,test
US20140274703A1,COC(=O)c1nc(-c2ccc(C(F)(F)F)nc2)c(C)c(N)c1Cl>>Cc1c(-c2ccc(C(F)(F)F)nc2)nc(C(=O)O)c(Cl)c1N,,CO,,Cl,[Na+].[OH-],test
US20130217680A1,CCOC(=O)C(C)(C(=O)OC(C)(C)C)c1ccc([N+](=O)[O-])nc1C>>CCOC(=O)C(C)c1ccc([N+](=O)[O-])nc1C,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110039831A1,C1CNCCN1.C[C@@H](c1c(F)cc2ncccc2c1F)c1cnc2ccc(Cl)nn12>>C[C@@H](c1c(F)cc2ncccc2c1F)c1cnc2ccc(N3CCNCC3)nn12,,CCOC(C)=O,CN1CCCC1=O,[F-].[K+],,test
US20110046097A1,Cc1ccnc(Cl)c1I.NN>>Cc1ccnc(NN)c1I,,c1ccncc1,,O,,test
US20070185109A1,CC(C)[NH-].O=C([O-])C1=C(c2ccccc2)c2ccc(O)cc2C1=O.OCCN1CCOCC1>>CC(C)[NH-].O=C([O-])C1=C(c2ccccc2)c2ccc(OCCN3CCOCC3)cc2C1=O,,C1CCOC1,c1ccccc1,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070123521A1,CC(=O)c1c(O)c2ccccc2oc1=O.O=Cc1ccc(OC(F)(F)F)c(Cl)c1>>O=C(C=Cc1ccc(OC(F)(F)F)c(Cl)c1)c1c(O)c2ccccc2oc1=O,,ClC(Cl)Cl,,C1CCNCC1,,test
US04910204,CC(=O)OC(C)=O.Cc1nc(N)[nH]c(=O)c1O>>CC(=O)Oc1c(C)nc(N)[nH]c1=O,,c1ccncc1,,,,test
US20070185143A1,CCOC(=O)c1nn(C)c2c1CCc1cnc(I)nc1-2.[NH4+]>>Cn1nc(C(N)=O)c2c1-c1nc(I)ncc1CC2,,CO,,O,,test
US20080070867A1,CCOC(=O)n1cc(-c2ccc(S(C)(=O)=O)cc2)n(Cc2ccc(C(F)(F)P(=O)(OCC)OCC)c(Br)c2)c1=O.CNC>>CCOP(=O)(OCC)C(F)(F)c1ccc(Cn2c(-c3ccc(S(C)(=O)=O)cc3)cn(C)c2=O)cc1Br,,C1CCOC1,,,,test
US20070117842A1,CC1(C)OC(=O)CC(=O)O1.CCOC(=O)c1ccc(N)cc1OC.CCOC([O-])[O-]>>CCOC(=O)c1ccc(NC=C2C(=O)OC(C)(C)OC2=O)cc1OC,,CC(C)O,,,,test
US20100190766A1,C#CC(C)(C)O.COC(=O)c1ccc(C=C(Br)Br)cc1>>COC(=O)c1ccc(C#CC#CC(C)O)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,,test
US20090137804A1,CN(C)c1cccc(Nc2cc(N)ncn2)c1.O=C=Nc1c(F)cccc1F>>CN(C)c1cccc(Nc2cc(NC(=O)Nc3c(F)cccc3F)ncn2)c1,,C1COCCO1,,CCOC(C)=O,,test
US04551534,COC(=O)C1=C(C)NC2=C(C(=O)CNC2)C1c1c(F)ccc(Cl)c1Cl.Cc1cccc(OCC2CO2)c1C>>COC(=O)C1=C(C)NC2=C(C(=O)CN(CC(O)COc3cccc(C)c3C)C2)C1c1c(F)ccc(Cl)c1Cl,,CO,Cl,,,test
US20080015203A1,C[C@@H](CO[Si](C)(C)C(C)(C)C)Oc1cc(OCc2ccccc2)cc(C(=O)O)c1.Cn1ccc(N)n1>>C[C@@H](CO[Si](C)(C)C(C)(C)C)Oc1cc(OCc2ccccc2)cc(C(=O)Nc2ccn(C)n2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050197350A1,Cc1cc(N[C@H]2CC[C@@H](NC(=O)OCc3ccccc3)CC2)nc2ccccc12>>Cc1cc(N[C@@H]2CC[C@H](N)CC2)nc2ccccc12,[Pd],CCO,,,,test
US20130059834A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](C(N)=O)C1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](C#N)C1,,C1CCOC1,,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US04172943,CC(Cl)C(=O)NC(N)=O.CCCCCC(C)C(C)c1cc(O)c2c(c1)OC(C)(C)C1=C2CNCC1>>CCCCCC(C)C(C)c1cc(O)c2c(c1)OC(C)(C)C1=C2CN(C(C)C(=O)NC(N)=O)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US20070155805A1,CCCCC(CCBr)c1sc2cc(F)ccc2c1C.CCOC(=O)COc1ccc(S)cc1C>>CCCCC(CCSc1ccc(OCC(=O)OCC)c(C)c1)c1sc2cc(F)ccc2c1C,,CC#N,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100009974A1,NC1CC1.NS(=O)(=O)c1cc(Cl)c(Cl)cc1F>>NS(=O)(=O)c1cc(Cl)c(Cl)cc1NC1CC1,,C1COCCO1,,,,test
US20060252931A1,COc1cc(C[C@@H](CC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)O)cc(C)c1OCc1ccccc1>>COc1cc(C[C@@H](CC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)O)cc(C)c1O,[Pd],CCN(CC)CC,CO,[H][H],,test
US20160075711A1,CC(C)(C)[Si](C)(C)OC1CCC(C(=O)CC2c3ccccc3-c3cncn32)CC1>>CC(C)(C)[Si](C)(C)OC1CCC(C(O)CC2c3ccccc3-c3cncn32)CC1,,CO,,[BH4-].[Na+],,test
US20050171110A1,Cc1ccccc1.O=c1c(Cl)c(Cl)c(OCc2ccccc2)nn1Cc1ccccc1.OB(O)c1ccc(Cl)cc1>>O=c1c(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)c(OCc2ccccc2)nn1Cc1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US04496734,CC(=O)OC(C)=O.COc1cccc(C#N)n1>>COc1cccc(CNC(C)=O)n1,[Ni],,,CC(=O)[O-].[Na+],,test
US20070191372A1,CN(CCNC(=O)C(F)(F)F)CCNc1n[n+]([O-])c2ccccc2[n+]1[O-].O=C(c1cccc2ccc(-c3ccncc3)nc12)n1ccnc1>>CN(CCNC(=O)c1cccc2ccc(-c3ccncc3)nc12)CCNc1n[n+]([O-])c2ccccc2[n+]1[O-],,CO,,N,,test
US20040044000A1,COC(=O)c1cccc(CBr)c1.Oc1nccc2ccc(Br)cc12>>COC(=O)c1cccc(Cn2ccc3ccc(Br)cc3c2=O)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05866612,CC(=N)NCc1cccc(CNC(=O)OC(C)(C)C)c1>>CC(=N)NCc1cccc(CN)c1,,C1COCCO1,CCOCC,Cl,,test
US20150307497A1,COC(=O)c1c(Cl)ncnc1Cl.OCc1ccc(F)cc1F>>COC(=O)c1c(Cl)ncnc1OCc1ccc(F)cc1F,,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US20110294807A1,CC(C)c1ccc(NC(=O)c2ccccc2N)cc1.Cc1cc(C=O)cc(C)c1OCCO>>Cc1cc(-c2nc3ccccc3c(=O)n2-c2ccc(C(C)C)cc2)cc(C)c1OCCO,Cl[Cu]Cl,CCO,,,,test
US20060094716A1,CC(C)(C)OC(=O)N[C@H]1CCNC1.O=CC(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N[C@H]1CCN(CC(c2ccccc2)c2ccccc2)C1,,C1CCOC1,ClCCl,,,test
US20060122173A1,COc1cc([N+](=O)[O-])cc2c1NC(Nc1ccccc1Cl)=NS2(=O)=O>>O=[N+]([O-])c1cc(O)c2c(c1)S(=O)(=O)N=C(Nc1ccccc1Cl)N2,,CS(C)=O,,[Cl-].[Li+],,test
US20150126498A1,Cc1cc(F)cc(Cl)c1.O=CN1CCOCC1>>Cc1cc(F)c(C=O)c(Cl)c1,,C1CCOC1,,[Li]CCCC,,test
US20030102459A1,C#CCO.CCC(CC)C[C@@H](C)OC(=O)c1ccc(I)cc1>>CCC(CC)C[C@@H](C)OC(=O)c1ccc(C#CCO)cc1,[Cu]I,CCN(CC)CC,,,,test
US20040058903A1,NCCc1ccccn1.O=[N+]([O-])c1ccc(F)c(Cl)c1>>O=[N+]([O-])c1ccc(NCCc2ccccn2)c(Cl)c1,,CN(C)C=O,,CCN(CC)CC,O,test
US20100048849A1,CCCCC1CCC(C(=O)Oc2ccc(/C=C/C(=O)O)cc2)CC1.O=[N+]([O-])c1ccc(CCO)c([N+](=O)[O-])c1>>CCCCC1CCC(C(=O)Oc2ccc(/C=C/C(=O)OCCc3ccc([N+](=O)[O-])cc3[N+](=O)[O-])cc2)CC1,CN(C)c1ccncc1,CCCCCC,Cc1ccccc1,O=S(Cl)Cl,c1ccncc1,test
US04115565,C1CSCCN1.COc1cc2nc(Cl)nc(N)c2cc1OC>>COc1cc2nc(N3CCSCC3)nc(N)c2cc1OC,,Clc1ccccc1,,,,test
US20080255150A1,COC(=O)Cc1ccc(Cl)cc1CO.C[C@H]1CN(C(=O)OC(C)(C)C)CCN1C(=O)Cc1ccc(Cl)cc1>>C[C@H]1CN(Cc2cc(Cl)ccc2CC(=O)O)CCN1C(=O)Cc1ccc(Cl)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030199562A1,C=C(C)c1cc(O)cc2nc(-c3ccc(O)cc3)oc12>>CC(C)c1cc(O)cc2nc(-c3ccc(O)cc3)oc12,[Pd],CCO,CCOC(C)=O,,,test
US05714479,COC(=O)c1nc(COCOCC[Si](C)(C)C)ccc1C(=O)c1ccc2c(c1)OCO2>>C[Si](C)(C)CCOCOCc1ccc(C(=O)c2ccc3c(c2)OCO3)c(C(=O)O)n1,,CO,,,,test
US20090186879A1,CCOC(=O)CCCn1c(Cl)nc2c(Cl)ccc(C(CC)CC)c21.Cc1cc(N2CCCC2)ncc1N>>CCOC(=O)CCCn1c(Nc2cnc(N3CCCC3)cc2C)nc2c(Cl)ccc(C(CC)CC)c21,,CCOC(C)=O,CN1CCCC1=O,Cc1ccc(S(=O)(=O)O)cc1,O,test
US07037929B1,CCCC(=O)Nc1ncc(CCC(C)=NN(C)C)s1.O>>CCCC(=O)Nc1ncc(CCC(C)=O)s1,,C1CCOC1,,,,test
US20040242580A1,CCC#CCCl.O=c1cnc(-c2ccc(Cl)cc2)n[nH]1>>CCC#CCn1nc(-c2ccc(Cl)cc2)ncc1=O,,CN(C)C=O,,[H-].[Na+],,test
US20090030003A1,COc1ccccc1-n1ncc(C#N)c1N.OO>>COc1ccccc1-n1ncc(C(N)=O)c1N,,[NH4+],[OH-],,,test
US20150291595A1,COc1ccc(B(O)O)c(OC)c1.Cc1ccn2nc([C@H](C)Nc3ncnc4c3c(Br)cn4COCC[Si](C)(C)C)n(-c3ccccc3)c(=O)c12>>COc1ccc(-c2cn(COCC[Si](C)(C)C)c3ncnc(N[C@@H](C)c4nn5ccc(C)c5c(=O)n4-c4ccccc4)c23)c(OC)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US20160083387A1,C=C1CC[C@H]2[C@H](OC(C)=O)[C@@H]([C@@]3(C)CC[C@H](O[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)C[C@@H]3CCO)CC[C@]12C.Clc1cnccn1>>C=C1CC[C@H]2[C@H](OC(C)=O)[C@@H]([C@@]3(C)CC[C@H](O[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)C[C@@H]3CCOc3cnccn3)CC[C@]12C,,CN(C)C=O,,[H-].[Na+],,test
US20120010241A1,CN1C(C)(C)CC(N)CC1(C)C.N#Cc1ncc(F)cc1F>>CN1C(C)(C)CC(Nc2cc(F)cnc2C#N)CC1(C)C,,CCOC(C)=O,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US20140357653A1,CC(C)(C)OC(=O)N1CC2(CC2)C[C@H]1CN1C(=O)c2ccccc2C1=O>>CC(C)(C)OC(=O)N1CC2(CC2)C[C@H]1CN,,CCO,,NN,O,test
US20100184815A1,CCCNC(=O)NNC(=O)[C@@H](C)OCc1ccccc1>>CCCn1c([C@@H](C)OCc2ccccc2)n[nH]c1=O,,CCO,,[K+].[OH-],,test
US07202221B2,NCCN.O=C(O)c1cn(C2CC2)c2cc(Cl)ccc2c1=O>>NCCNc1ccc2c(=O)c(C(=O)O)cn(C3CC3)c2c1,,CN1CCCC1=O,CO,ClCCl,,test
US20100087433A1,COc1ccc(C=O)cc1OC1CCCC1.Nc1ccc(I)cn1>>COc1ccc(CNc2ccc(I)cn2)cc1OC1CCCC1,,CC(Cl)Cl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100113511A1,CCCCc1ccc(C#CCCBr)cc1.CCc1cccnc1>>CCCCc1ccc(C#CCC[n+]2cccc(CC)c2)cc1.[Br-],,CC#N,,,,test
US05688796,COc1ccc(-c2sc3cc(OC)ccc3c2C(=O)c2ccc(OCCN3CCCCC3)nc2)cc1>>O=C(c1ccc(OCCN2CCCCC2)nc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12,,CC(Cl)Cl,,ClB(Cl)Cl,,test
US20080319074A1,C=CCC(CC=C)(COc1ccc(-c2ccc(C(F)(F)F)cc2)cc1)c1ccc(C(=O)NCCC(=O)OC)cc1>>C=CCC(CC=C)(COc1ccc(-c2ccc(C(F)(F)F)cc2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1,,C1CCOC1,,Cl,[Li+].[OH-],test
US04401660,O=C(O)COc1ccccc1.O=C1CCC(=O)N1O>>O=C(COc1ccccc1)ON1C(=O)CCC1=O,,CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20130281438A1,CC(=O)OC(C)=O.Nc1ccccc1N>>CC(=O)Nc1ccccc1N,,ClCCl,,,,test
US20060004003A1,CCOC(=O)c1c(C)nc2c(cnn2CC)c1-c1cncc(Br)c1>>CCn1ncc2c(-c3cncc(Br)c3)c(CO)c(C)nc21,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110056508A1,C1=NCCc2ccccc21.COS(=O)(=O)c1ccc(C)cc1>>CN1CCc2ccccc2C1.Cc1ccc(S(=O)(=O)O)cc1,,Cc1ccccc1,,,,test
US20090221555A1,COc1cccc(F)c1Nc1nc(Cl)ncc1Cl>>Oc1cccc(F)c1Nc1nc(Cl)ncc1Cl,,ClCCl,,BrB(Br)Br,,test
US20070060589A1,COC(=O)c1cncn1-c1cccc(CNC(=O)[C@H](C)C(=O)OC(C)(C)C)c1.NN>>C[C@@H](C(=O)NCc1cccc(-n2cncc2C(=O)NN)c1)C(=O)OC(C)(C)C,,CCO,,O,,test
US20150119373A1,CC1(C)CC(=O)OC1=O.CCN1CCN(C(=O)[C@]23CC[C@@H](C4(C)CC4)[C@@H]2[C@H]2CC[C@H]4[C@@](C)(CC[C@H]5C(C)(C)[C@@H](O)CC[C@@]54C)[C@]2(C)CC3)CC1>>CCN1CCN(C(=O)[C@]23CC[C@@H](C4(C)CC4)[C@@H]2[C@H]2CC[C@H]4[C@@](C)(CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(=O)O)CC[C@@]54C)[C@]2(C)CC3)CC1,CN(C)c1ccncc1,Cc1ccccc1,ClCCl,,,test
US20130289238A1,C[C@H](F)C(=O)O.NNC(N)=S>>C[C@H](F)c1nnc(N)s1,,C1COCCO1,,O=P(Cl)(Cl)Cl,,test
US20130079321A1,Cn1ncc([N+](=O)[O-])c1N1CCC(O)C(C)(NC(=O)C(F)(F)F)CC1>>Cn1ncc(N)c1N1CCC(O)C(C)(NC(=O)C(F)(F)F)CC1,[Pd],CO,,O=C[O-].[NH4+],,test
US20080242665A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.OCc1ccc(Br)cn1>>CC(C)(C)[Si](OCc1ccc(Br)cn1)(c1ccccc1)c1ccccc1,,ClCCl,,c1c[nH]cn1,,test
US03957783,CC(=O)Nc1scc(C)c1C(=O)c1ccccc1Cl.CI>>CCC(=O)Nc1scc(C)c1C(=O)c1ccccc1Cl,,CN(C)C=O,,O,[H-].[Na+],test
US20110152243A1,O=Cc1ccncc1.c1ccc2[nH]ccc2c1>>OC(c1ccncc1)c1c[nH]c2ccccc12,,CO,O,[Na+].[OH-],,test
US05866576,C=CCCCCBr.CCC(C)(C)C(=O)n1cnc2c1c(=O)[nH]c(=O)n2C>>C=CCCCCn1c(=O)c2c(ncn2C(=O)C(C)(C)CC)n(C)c1=O,,CCOC(C)=O,CS(C)=O,O,[H-].[Na+],test
US20130338141A1,COC(=O)c1nc(C(CCC(C)(CO[Si](C)(C)C(C)(C)C)OC)N(C)C(=O)OC(C)(C)C)[nH]c(=O)c1O.Cc1cc(CN)ccc1F>>COC(C)(CO)CCC(c1nc(C(=O)NCc2ccc(F)c(C)c2)c(O)c(=O)[nH]1)N(C)C(=O)OC(C)(C)C,,CC(C)O,,,,test
US20070249599A1,O=C1NC(=Nc2ccccc2Br)SC1=Cc1ccc2nsnc2c1>>Nc1ccc(C=C2SC(Nc3ccccc3Br)=NC2=O)cc1N,,CCO,,[Cl-].[NH4+],,test
US20060019965A1,Cc1ccc(N)c(N)n1.O=CC=O>>Cc1ccc2nccnc2n1,,CO,,,,test
US20130029846A1,CN(C)C=Nc1ccc2[nH]ccc2c1.CON=C(CCl)CCl>>CON=C(CCl)Cn1ccc2cc(N=CN(C)C)ccc21,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20110212945A1,COC(=O)c1cc(C2CC2)ccc1Nc1cnc(-c2ccccc2Cl)nc1>>O=C(O)c1cc(C2CC2)ccc1Nc1cnc(-c2ccccc2Cl)nc1,,CO,O,[Na+].[OH-],,test
US20100094000A1,CC1(C)OB(c2ccc3c(c2)NC(=O)CO3)OC1(C)C.Cc1nn(C[C@@H]2CCC(=O)O2)c(-c2ccc(F)cc2)c1Br>>Cc1nn(C[C@@H]2CCC(=O)O2)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2,,C1CCOC1,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US03976653,C=O.Oc1ccc2c(c1)C[C@H]1CCCN[C@H]1C2>>CN1CCC[C@@H]2Cc3cc(O)ccc3C[C@@H]21,[Pd],CCO,,[H][H],,test
US20030171370A1,CCN(CC)C(=O)c1ccc(C=O)cc1.COc1ccccc1Br>>CCN(CC)C(=O)c1ccc(C(O)c2ccccc2OC)cc1,,C1CCOC1,,[Mg],[Cl-].[NH4+],test
US20110039832A1,CI.COc1cc2c(cc1OC(C)C)-c1c(-c3cccs3)c(CO)c(C(=O)N(C)C(C)(C)C)n1CC2>>COCc1c(-c2cccs2)c2n(c1C(=O)N(C)C(C)(C)C)CCc1cc(OC)c(OC(C)C)cc1-2,,C1CCOC1,,O,[H-].[Na+],test
US20150252032A1,C[C@@]1(C(=O)O)CCCN1.Cc1ccc(-n2nccn2)c(C(=O)Cl)c1>>Cc1ccc(-n2nccn2)c(C(=O)N2CCC[C@@]2(C)C(=O)O)c1,,ClCCl,c1ccncc1,Cl,,test
US20090099184A1,N#Cc1cccc(O)c1.O=C(NCc1ccc(Cl)cc1Cl)c1ccnc(F)c1>>N#Cc1cccc(Oc2cc(C(=O)NCc3ccc(Cl)cc3Cl)ccn2)c1,,CC(=O)N(C)C,,[H-].[Na+],,test
US05495046,CCOC(=O)C=Cc1cc(Cl)ccc1OCCc1ccccc1>>CCOC(=O)CCc1cc(Cl)ccc1OCCc1ccccc1,O=[Pt]=O,CCOC(C)=O,,[H][H],,test
US20070010511A1,CN.COCCCOc1cc(COC2CN(C(=O)OCc3ccccc3)CCC2c2ccc(OCCCOCc3ccccc3OC)cc2)ccc1C(=O)Cl>>CNC(=O)c1ccc(COC2CN(C(=O)OCc3ccccc3)CCC2c2ccc(OCCCOCc3ccccc3OC)cc2)cc1OCCCOC,,Cc1ccccc1,,,,test
US05166198,Nc1ncnc2c1ncn2OCc1ccccc1.O=C(Cl)c1ccccc1C(=O)Cl>>O=C1c2ccccc2C(=O)N1c1ncnc2c1ncn2OCc1ccccc1,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20150073019A1,CCOC(=O)CC(=O)c1cccc(OC)c1.NNc1nc2ccccc2s1>>COc1cccc(-c2cc(=O)n(-c3nc4ccccc4s3)[nH]2)c1,,CCO,,,,test
US20140094474A1,C#CC(=O)OCC.NC(CC(F)(F)F)=NO>>CCOC(=O)C=CON=C(N)CC(F)(F)F,,CC#N,,CCN(CC)CC,,test
US20120115811A1,O=[N+]([O-])c1cccc(Br)c1.OB(O)c1ccncc1>>O=[N+]([O-])c1cccc(-c2ccncc2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],O=C([O-])O.[Na+],test
US20130123500A1,Cn1nccc1N.O=C(Cl)c1ccc(C(F)(F)F)cc1>>Cn1nccc1NC(=O)c1ccc(C(F)(F)F)cc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US05589473,C=CCBr.COc1cc(O)c2c(c1C)C(=O)OC2O>>C=CCOC(=O)c1c(C)c(OC)cc(O)c1C=O,,CN(C)C=O,,CN(C)C(=N)N(C)C,,test
US05746840,CC(C)(C)OC(=O)NN.Cn1nnc2ccc(C(=O)c3ccc(Cl)cc3)cc21>>Cn1nnc2ccc(C(=NNC(=O)OC(C)(C)C)c3ccc(Cl)cc3)cc21,,CCO,,,,test
US04933333,COc1ccc(COC(=O)[C@H]2C[C@H](OC=O)CN2C(=O)OCc2ccc([N+](=O)[O-])cc2)cc1>>COc1ccc(COC(=O)[C@H]2C[C@H](O)CN2C(=O)OCc2ccc([N+](=O)[O-])cc2)cc1,,C1CCOC1,CCOC(C)=O,[Na+].[OH-],,test
US04420487,Nc1cc(Cl)c(S(N)(=O)=O)cc1N.S=C=S>>NS(=O)(=O)c1cc2[nH]c(S)nc2cc1Cl,,CCO,CO,O,[K+].[OH-],test
US05350748,CC(C)S.COC(=O)c1sc2cccc(Cl)c2c1Br>>COC(=O)c1sc2cccc(Cl)c2c1SC(C)C,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20100093788A1,CC(C)(C)OC(=O)Nc1ccc(-c2ccccc2OC(F)(F)F)cc1NC(=O)OC(C)(C)C.COC(=N)C(Cl)(Cl)Cl>>FC(F)(F)Oc1ccccc1-c1ccc2[nH]c(C(Cl)(Cl)Cl)nc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130121994A1,Clc1ncccc1Br.OCC(F)(F)F>>FC(F)(F)COc1ncccc1Br,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US04554280,NNC(N)=O.O=Cc1c(O)c(O)cc2ccccc12>>NC(=O)NN=Cc1c(O)c(O)cc2ccccc12,,CO,O,Cl,CC(=O)[O-].[Na+],test
US20120178955A1,C=C[Si](C)(C)N[Si](C)(C)C1(C#CO[Si](C)(C)C)CCCCC1.C=Cc1ccc(Cl)cc1>>C[Si](C)(/C=C/c1ccc(Cl)cc1)N[Si](C)(C)C1(C#CO[Si](C)(C)C)CCCCC1,,Cc1ccccc1,,,,test
US04252814,N#CCS.O=C(Cl)c1ccco1>>N#CCSC(=O)c1ccco1,,CCOCC,,c1ccncc1,,test
US04988689,Fc1ccc(Cn2c(NC3CCN(CCN=C=S)C3)nc3ccccc32)cc1.Nc1ccncc1N>>Nc1ccncc1NC(=S)NCCN1CCC(Nc2nc3ccccc3n2Cc2ccc(F)cc2)C1,,C1CCOC1,,,,test
US20090029905A1,Cc1cc(NC(=O)c2cc(O)cc(OC(CF)CF)c2)nn1C.O=C(c1cnc(Cl)c(Cl)c1)N1CCC1>>Cc1cc(NC(=O)c2cc(Oc3ncc(C(=O)N4CCC4)cc3Cl)cc(OC(CF)CF)c2)nn1C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05292766,CCCN(CCC)C1CCc2cccc(C(C)=O)c2C1.CN(C)C(N(C)C)N(C)C>>CCCN(CCC)C1CCc2cccc(C(=O)C=CN(C)C)c2C1,,Cc1ccccc1,,,,test
US20070259877A1,COc1ccc(N2C[C@H](C)N[C@H](C)C2)cc1NS(=O)(=O)c1ccc(Br)cc1.OB(O)c1ccco1>>COc1ccc(N2C[C@H](C)N[C@H](C)C2)cc1NS(=O)(=O)c1ccc(-c2ccco2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,CC(C)(C)[O-].[K+],,test
US03993683,CCSCC(=O)c1ccc(-c2ccccc2F)cc1.OO>>CCS(=O)CC(=O)c1ccc(-c2ccccc2F)cc1,,CC(=O)O,,,,test
US04559339,CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)N1CC(CC2NC(=O)c3ccccc3-n3c2nc2ccccc2c3=O)c2ccccc21.O>>CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)N1CC(CC2NC(=O)c3ccccc3-n3c2nc2ccccc2c3=O)c2ccccc21.O,,CC(=O)O,,[BH3-]C#N.[Na+],,test
US05194442,C1=Cc2cc(Sc3ccccc3)ccc2OCC1.OO>>O=S(c1ccccc1)c1ccc2c(c1)C=CCCO2,,CC(=O)O,,,,test
US20110112127A1,CC(C)[Si](Cl)(C(C)C)C(C)C.Cc1ncnc2[nH]cc(I)c12>>Cc1ncnc2c1c(I)cn2[Si](C(C)C)(C(C)C)C(C)C,,C1CCOC1,,O,[H-].[Na+],test
US20120184587A1,COC(=O)c1cc(SC)c(O)c(C(C)(C)C)c1.COS(=O)(=O)OC>>COC(=O)c1cc(SC)c(OC)c(C(C)(C)C)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040186060A1,COC(=O)C(N)(CCSC)Cc1cccc(C#N)c1.COC(=O)Cl>>COC(=O)NC(CCSC)(Cc1cccc(C#N)c1)C(=O)OC,,CC#N,CCOC(C)=O,CCN(CC)CC,Cl,test
US20150057265A1,CC(C)(C)OC(=O)N[C@@H]1CN(c2ccncc2[N+](=O)[O-])C[C@H](C2CC2)[C@H]1O[Si](C)(C)C(C)(C)C>>CC(C)(C)OC(=O)N[C@@H]1CN(c2ccncc2N)C[C@H](C2CC2)[C@H]1O[Si](C)(C)C(C)(C)C,[Pd],,,,,test
US20150307451A1,CI.Cc1c(Br)cc(C(=O)O)c(N)c1C>>COC(=O)c1cc(Br)c(C)c(C)c1N,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20150336894A1,CCN(C(=O)OC(C)(C)C)c1cnccc1C#Cc1ccc(C(C)(C)C)cc1>>CCNc1cnccc1C#Cc1ccc(C(C)(C)C)cc1,,CCOC(C)=O,,Cl,[Na+].[OH-],test
US20090264406A1,C[Mg]Br.Cn1cc(-c2ccc3ncc(C(=O)c4c(F)cc5ncccc5c4F)n3n2)cn1>>Cn1cc(-c2ccc3ncc(C(C)(O)c4c(F)cc5ncccc5c4F)n3n2)cn1,,C1CCOC1,,,,test
US05998433,CN(C)Cc1cc2c(o1)CN(S(=O)(=O)c1ccc(C(=O)c3ccccc3)cc1)CC2.Cl>>CN(C)Cc1cc2c(o1)CN(S(=O)(=O)c1ccc(C(=O)c3ccccc3)cc1)CC2.Cl,,CO,,,,test
US04486432,Nc1cccc(F)c1.Oc1ccc(O)c2nccnc12>>O=C1C=C(Nc2cccc(F)c2)C(=O)c2nccnc21,O=[Ag-],CCO,,,,test
US20080255180A1,O=C1c2ccccc2C(=O)N1Oc1ccc(Cl)cc1>>NOc1ccc(Cl)cc1,,CO,ClC(Cl)Cl,NN,O,test
US20100168418A1,CNC(=O)c1cc(OC)cc2c1ccc(=O)n2CCN1CCC(N(Cc2ccc3c(c2)OCCO3)C(=O)OC(C)(C)C)CC1.Cl>>CNC(=O)c1cc(OC)cc2c1ccc(=O)n2CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1.Cl,,CCOC(C)=O,,,,test
US20130274269A1,C[C@H](O)CN(Cc1ccccc1)C(=O)OC(C)(C)C.O=C1NC(=O)c2ccccc21>>C[C@H](CN(Cc1ccccc1)C(=O)OC(C)(C)C)N1C(=O)c2ccccc2C1=O,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140206703A1,CC(C)(C)OC(=O)N1CCC[C@H](C(=O)O)C1.NCCO>>CC(C)(C)OC(=O)N1CCC[C@H](C(=O)NCCO)C1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090143427A1,CC(C)[C@H](N)CO.CCOC(=O)/C(=C\N(C)C)C(=O)c1cc(I)c(F)cc1F>>CCOC(=O)/C(=C\N[C@H](CO)C(C)C)C(=O)c1cc(I)c(F)cc1F,,C1CCOC1,,,,test
US06214873B1,CCOC(=O)C(CCc1ccc(C2(CCCCc3ccccc3)OCCO2)cc1)(NC(C)=O)C(=O)OCC>>CC(=O)NC(CO)(CO)CCc1ccc(C2(CCCCc3ccccc3)OCCO2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20140171408A1,Nc1ccnc(Cl)c1F.O=C(Cl)c1c(Cl)cccc1Cl>>O=C(Nc1ccnc(Cl)c1F)c1c(Cl)cccc1Cl,,C1COCCO1,,CCN(CC)CC,,test
US20090048239A1,C=CCc1cccc(-c2[nH]c3cc(C(=O)OC)ccc3c2C2CCCCC2)c1O>>CCCc1cccc(-c2[nH]c3cc(C(=O)OC)ccc3c2C2CCCCC2)c1O,[Pd],CCOC(C)=O,,,,test
US04663347,CCOC(=O)c1oc2cc(O)ccc2c1C.O=[N+]([O-])O>>CCOC(=O)c1oc2c([N+](=O)[O-])c(O)ccc2c1C,,CC(=O)O,,,,test
US20060155121A1,Cc1cc([N+](=O)[O-])cc(C)c1NC(=O)CC1CCCC1>>Cc1cc(N)cc(C)c1NC(=O)CC1CCCC1,[Zn],C1CCOC1,CC(=O)O,O=C([O-])[O-].[Na+].[Na+],,test
US20090270402A1,CC(C)c1nnc2ccc(Cl)nn12.CCOC(=O)CC#N>>CCOC(=O)C(C#N)c1ccc2nnc(C(C)C)n2n1,,CN(C)C=O,,[H-].[Na+],,test
US20040006096A1,CCOc1cc([C@@H](CC(=O)O)N2Cc3ccccc3C2=O)ccc1OC.NO>>CCOc1cc([C@@H](CC(=O)NO)N2Cc3ccccc3C2=O)ccc1OC,,C1CCOC1,,Cl,O=C(n1ccnc1)n1ccnc1,test
US20110190334A1,CSC(=C[N+](=O)[O-])SC.NCCS>>O=[N+]([O-])C=C1NCCS1,,CCCCCC,CCO,CCOC(C)=O,,test
US20100273770A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c3OCCN(C(=O)OC(C)(C)C)C4CCCC(=O)O)no2)cc1C#N.Cl>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3OCCNC4CCCC(=O)O)no2)cc1C#N.Cl,,C1COCCO1,,,,test
US20090082434A1,Cc1ccc(S(=O)(=O)OCC2Cc3cccc(Br)c3O2)cc1.OB(O)c1cccc(C(F)(F)F)c1>>Cc1ccc(S(=O)(=O)OCC2Cc3cccc(-c4cccc(C(F)(F)F)c4)c3O2)cc1,Cc1ccccc1[P](c1ccccc1C)(c1ccccc1C)[Pd](Cl)(Cl)[P](c1ccccc1C)(c1ccccc1C)c1ccccc1C,,,O=C([O-])[O-].[K+].[K+],,test
US20020119992A1,CC(C)[Si](OCc1cc(Cl)ccc1C1CC(=O)N1)(C(C)C)C(C)C.Cl>>Cl.OCc1cc(Cl)ccc1C1CCN1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100048637A1,CC(C)(C)OC(=O)NC1CCC(NCc2cccc(-c3ccncc3)c2)CC1.O=C(Cl)c1sc2ccccc2c1Cl>>CC(C)(C)OC(=O)NC1CCC(N(Cc2cccc(-c3ccncc3)c2)C(=O)c2sc3ccccc3c2Cl)CC1,,ClCCl,,CCN(CC)CC,,test
US20070244159A1,CCOC(=O)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc2[nH]1>>O=C(O)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc2[nH]1,,C1COCCO1,O,Cl,[Li+].[OH-],test
US20160016938A1,COC(=O)c1ccc2c(SC)n[nH]c2c1.Clc1ncc(Br)cn1>>COC(=O)c1ccc2c(SC)nn(-c3ncc(Br)cn3)c2c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070003539A1,Cc1ccccc1Br.N#Cc1ccccc1B(O)O>>Cc1ccccc1-c1ccccc1C#N,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20130196974A1,CC(=O)OC(C)=O.Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)nc(N)c2c1>>CC(=O)Nc1nc(N2CCS(=O)(=O)c3ccccc3C2)nc2ccc(C)cc12,,CCOC(C)=O,,,,test
US20090175794A1,CC(C)(C)OC(=O)Nc1ccc(O)cc1.Cc1ccc(S(=O)(=O)OCCOCCOCCN=[N+]=[N-])cc1>>CC(C)(C)OC(=O)Nc1ccc(OCCOCCOCCN=[N+]=[N-])cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110028487A1,COc1ccc(F)cc1S(=O)(=O)N1CCOCC1>>O=S(=O)(c1cc(F)ccc1O)N1CCOCC1,,ClCCl,,BrB(Br)Br,CO,test
US20160145270A1,CO.COC(=O)c1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)nc1F>>COC(=O)c1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)nc1OC,,CO,ClCCl,CC(C)(C)[O-].[K+],,test
US20050119295A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.NCc1ccccc1.O=[N+]([O-])C=Cc1ccc(OC(F)(F)F)cc1>>FC(F)(F)Oc1ccc(-c2cn(Cc3ccccc3)c3c2CNCC3)cc1,,ClCCl,,,,test
US04391808,N#CBr.S=C1Nc2ccccc2Sc2nccn21>>N#CSC1=Nc2ccccc2Sc2nccn21,,C1CCOC1,,[H-].[Na+],,test
US20150148342A1,CCI.Cc1ccc(S(=O)(=O)n2ccc3c(-c4ccc5c(ncn5C)c4Oc4ccc(F)cc4F)c[nH]c(=O)c32)cc1>>CCn1cc(-c2ccc3c(ncn3C)c2Oc2ccc(F)cc2F)c2ccn(S(=O)(=O)c3ccc(C)cc3)c2c1=O,,C1CCOC1,C1CCOC1,CC(C)(C)[O-].[K+],,test
US05959107,Cc1nc2cc(F)c([N+](=O)[O-])cc2s1.Sc1cccc2cnccc12>>Cc1nc2cc(Sc3cccc4cnccc34)c([N+](=O)[O-])cc2s1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US07867990B2,OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O>>OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)OC(O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O,,O,,,,test
US05401848,CC1(C)CC(NC(=O)Nc2ccccc2)c2cc(C#N)ccc21.O=C=NCc1ccccc1>>CC1(C)CC(NC(=O)NCc2ccccc2)c2cc(C#N)ccc21,,CCO,,,,test
US20160257682A1,Brc1cc2[nH]nc(I)c2cn1.CC(C)I>>CC(C)n1nc(I)c2cnc(Br)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20060293352A1,CC(C)(C)OC(=O)CBr.CCS(=O)(=O)c1ccc(Sc2cc(Cl)ccc2O)cc1>>CCS(=O)(=O)c1ccc(Sc2cc(Cl)ccc2OCC(=O)OC(C)(C)C)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120028952A1,COC(=O)c1ccc(-c2ncnc(C)c2C#Cc2ccc(N)nc2)cc1>>Cc1ncnc(-c2ccc(C(=O)O)cc2)c1C#Cc1ccc(N)nc1,,C1CCOC1,O,[Li+].[OH-],,test
US03948944,BrP(Br)Br.OCC1CSC(c2ccccc2)S1>>BrCC1CSC(c2ccccc2)S1,,CCOCC,,O=C([O-])O.[Na+],,test
US20130336920A1,CC(C)(C)OC(=O)CCSCc1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)NCc3ccc(N4CCOCC4)cc3)ccn2)c1>>O=C(O)CCSCc1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)NCc3ccc(N4CCOCC4)cc3)ccn2)c1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20020068734A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)c1cccc(N)c1.COc1cc2ncnc(N3CCNCC3)c2cc1OC>>COc1cc2ncnc(N3CCN(C(=O)Nc4cccc(C(C)C)c4)CC3)c2cc1OC,CN(C)c1ccncc1,ClCCl,,,,test
US20150065705A1,BrC(Br)(Br)Br.Cc1cc(CO)sc1Br>>Cc1cc(CBr)sc1Br,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090048258A1,C[Si](C)(C)CCO.O=C(O)c1cn(Cc2ccccc2)nc1-c1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>C[Si](C)(C)CCOC(=O)Nc1cn(Cc2ccccc2)nc1-c1ccccc1,,C1CCOC1,CCN(CC)CC,O=C([O-])O.[Na+],,test
US20100120801A1,CC(C)(C)OC(=O)N1CCC(c2nc(-c3ccc(F)c(Cl)c3)c[nH]2)CC1.CN(C)CCCl>>CN(C)CCn1cc(-c2ccc(F)c(Cl)c2)nc1C1CCN(C(=O)OC(C)(C)C)CC1,,CS(C)=O,ClCCl,Cl,[K+].[OH-],test
US20150051209A1,CC(C)(C)OC(=O)N1CCC(N=[N+]=[N-])C(F)C1>>CC(C)(C)OC(=O)N1CCC(N)C(F)C1,[Pd],CCO,,,,test
US04332820,CN(C)S(=O)(=O)c1ccc(O)cc1.N#Cc1cc([N+](=O)[O-])ccc1Cl>>CN(C)S(=O)(=O)c1ccc(Oc2ccc([N+](=O)[O-])cc2C#N)cc1,,CS(C)=O,,O,[Na+].[OH-],test
US20050288367A1,CNC(=O)COc1ccc(O)cc1.N#Cc1ccc(CBr)cc1>>CNC(=O)COc1ccc(OCc2ccc(C#N)cc2)cc1,,CCC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050267105A1,Cc1ccc(F)cc1C(=O)N1CCOCC1.O=C1CCC(=O)N1Br>>O=C(c1cc(F)ccc1CBr)N1CCOCC1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20110144105A1,O=S(=O)(CCO)c1ccc(C(CC2CCCC2)c2cc3cccnc3[nH]2)cc1>>C=CS(=O)(=O)c1ccc(C(CC2CCCC2)c2cc3cccnc3[nH]2)cc1,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20060094747A1,CCOC(=O)/C=C/c1ccc(Br)cc1.OB(O)c1ccc(-c2cccc3c2oc2ccccc23)cc1>>CCOC(=O)C=Cc1ccc(-c2ccc(-c3cccc4c3oc3ccccc34)cc2)cc1,,CO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20040242572A1,CCOC(=O)c1ccc(-c2ccc(Cl)cc2)cc1CBr.NCCc1ccc(CN2CCCC2)cc1>>O=C1c2ccc(-c3ccc(Cl)cc3)cc2CN1CCc1ccc(CN2CCCC2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080214529A1,CCOC(=O)C1CCCCN1N(CCC(C)(C)C)C(=O)CC1=NS(=O)(=O)c2cc(NS(C)(=O)=O)ccc2N1>>CC(C)(C)CCN1C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)C2CCCCN21,,CCO,,C,C[O-].[Na+],test
US20140349972A1,CCOP(=O)(OCC)c1ccc(C(C(=O)O)c2ccccc2)cc1.Nc1cnc(-n2cccn2)nc1O>>CCOP(=O)(OCC)c1ccc(C(C(=O)Nc2cnc(-n3cccn3)nc2O)c2ccccc2)cc1,,CC#N,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090036443A1,CN.O=C(O)c1cc2c(s1)c(C1CCCCC1)c(-c1ccc(Cl)cc1)n2CC(=O)N1CCOCC1>>CNC(=O)c1cc2c(s1)c(C1CCCCC1)c(-c1ccc(Cl)cc1)n2CC(=O)N1CCOCC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090291951A1,CSc1nccc(COS(C)(=O)=O)n1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1nccc(COS(C)(=O)=O)n1,,CCOC(C)=O,ClCCl,,,test
US20110257151A1,COC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(N)c1)N2.Cl.O=S=O>>COC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(S(=O)(=O)Cl)c1)=N2,,CC(=O)O,O,O=N[O-].[Na+],,test
US20030171583A1,Fc1nc(Cl)c2[nH]cnc2n1.Sc1ccccc1>>Fc1nc(Sc2ccccc2)c2[nH]cnc2n1,,CO,,CCN(C(C)C)C(C)C,,test
US20120142681A1,N#Cc1cnc2nnn(Cc3ccc4ncccc4c3)c2n1.NN>>NN=C(N)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1,,CCO,,O,,test
USRE037556E1,C=CCC1(O)C=CC(c2csc(-c3ccc(OCC)c(OCC)c3)n2)=CC1C(=O)OC.CO.O=[Os](=O)(=O)=O>>CCOc1ccc(-c2nc(-c3cc(CC(O)CO)c(O)c(C(=O)OC)c3)cs2)cc1OCC,O=[Os](=O)(=O)=O,C1CCOC1,CO,,,test
US20160244409A1,CC1(C)CC(=O)OC(=O)C1.CCON>>CCONC(=O)CC(C)(C)CC(=O)O,,ClCCl,,CCN(CC)CC,Cl,test
US06316444B1,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C(CO)C1.CCN(C(C)C)C(C)C>>CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C(CN)C1,,CCOC(C)=O,ClCCl,CS(=O)(=O)Cl,,test
US20090105211A1,Cc1ccc(C#N)cc1N.O=C(O)c1ccc(Nc2nc(-c3ccccc3)c3ccccc3n2)cc1>>Cc1ccc(C#N)cc1NC(=O)c1ccc(Nc2nc(-c3ccccc3)c3ccccc3n2)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110217311A1,CO[C@H]1CCC[C@H](Oc2ncccc2Nc2ncnc3sc(C(=O)O)c(C)c23)C1.N>>CO[C@H]1CCC[C@H](Oc2ncccc2Nc2ncnc3sc(C(N)=O)c(C)c23)C1,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,test
US20040097571A1,CSc1ccccc1CC[C@H]([C@H](C)O)n1cnc(C(N)=O)c1.O=C(OO)c1cccc(Cl)c1>>C[C@H](O)[C@@H](CCc1ccccc1S(C)=O)n1cnc(C(N)=O)c1,,ClCCl,,,,test
US20030158413A1,O=C(N[C@H]1CCSc2cc(C(=O)Nc3ccnc4c3ccn4CO)ccc21)OCc1ccccc1>>O=C(N[C@H]1CCSc2cc(C(=O)Nc3ccnc4[nH]ccc34)ccc21)OCc1ccccc1,,C1CCOC1,CO,O,CC(=O)[O-].[Na+],test
US20040138269A1,Cc1ccc(S(=O)(=O)n2cc(-c3cccc(C(=O)Nc4cccc(C(F)(F)F)c4)c3)cc2C(=O)NCCN2CCOCC2)cc1>>O=C(Nc1cccc(C(F)(F)F)c1)c1cccc(-c2c[nH]c(C(=O)NCCN3CCOCC3)c2)c1,,CO,,[Na+].[OH-],,test
US20090192156A1,C=CC(=O)OC.[C-]#[N+]C(C)S(=O)(=O)c1ccc(C)cc1>>COC(=O)c1c[nH]c(C)c1,,CCOCC,CS(C)=O,[H-].[Na+],,test
US04517185,CC(C)Br.N#CC1=C(c2ccccc2)C(O)(c2ccccc2)NC1=S>>CC(C)SC1=C(C#N)C(c2ccccc2)(c2ccccc2)C(=O)N1,,CCO,,[Na],,test
US20080004271A1,CS(=O)c1nc(-c2ccc(Cl)c(Cl)c2)c2c(N)c(C(N)=O)sc2n1.C[C@H](O)CN>>C[C@H](O)CNc1nc(-c2ccc(Cl)c(Cl)c2)c2c(N)c(C(N)=O)sc2n1,,CS(C)=O,,,,test
US20100063037A1,NCc1ccc2c(c1)COC(N[C@@H]1CCc3ccccc31)=N2.O=C(Cl)c1ccc(F)cc1>>O=C(NCc1ccc2c(c1)COC(N[C@@H]1CCc3ccccc31)=N2)c1ccc(F)cc1,,C1CCOC1,,CCN(CC)CC,O,test
US20100069381A1,C1COCCN1.Cc1nnc(-c2ccc3occ(C(=O)O)c3c2)o1>>Cc1nnc(-c2ccc3occ(C(=O)N4CCOCC4)c3c2)o1,CN(C)C=O,C1CCOC1,CCOC(C)=O,O=C(Cl)C(=O)Cl,O=C([O-])O.[Na+],test
US20080293771A1,CC(C)(C)OC(=O)N1CC[C@@H](N)C1.O=C(O)c1ccc(-n2cc3ccccc3n2)cc1>>CC(C)(C)OC(=O)N1CC[C@@H](NC(=O)c2ccc(-n3cc4ccccc4n3)cc2)C1,,CO,,,,test
US20130150339A1,CC(C)CO.COc1nc(F)ccc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12>>COc1nc(OCC(C)C)ccc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12,,CN(C)C=O,,[H-].[Na+],,test
US20020193596A1,COC(=O)[C@H](CCSC)NC(=O)c1ccc(C=Cn2ccnc2)cc1-c1ccccc1C>>COC(=O)[C@H](CCSC)NC(=O)c1ccc(CCn2ccnc2)cc1-c1ccccc1C,[Pd],CO,,,,test
US20140205566A1,CC(C)OC(=O)[C@H](C)N.O=P(Cl)(Cl)Oc1ccc(Cl)cc1.Oc1c(F)c(F)c(F)c(F)c1F>>CC(C)OC(=O)[C@H](C)NP(=O)(Oc1ccc(Cl)cc1)Oc1c(F)c(F)c(F)c(F)c1F,,ClCCl,,CCN(CC)CC,Cl,test
US20130116289A1,C[C@@H](NC(CO[Si](C)(C)C(C)(C)C)c1ccc(C#N)cc1)C(=O)OC(C)(C)C.NO>>C[C@@H](NC(CO[Si](C)(C)C(C)(C)C)c1ccc(/C(N)=N/O)cc1)C(=O)OC(C)(C)C,,CCO,,,,test
US20160145252A1,C[C@@H](N[C@@H]1CCCC(F)(F)[C@H]1O)c1ccccc1>>N[C@@H]1CCCC(F)(F)[C@H]1O,[Pd],CO,,,,test
US20070167443A1,CCOC(=O)C(=CNc1ccccc1)C(=O)c1cnc(C)c(C)c1>>Cc1cc(C(=O)c2c[nH]c3ccccc3c2=O)cnc1C,,c1ccc(Oc2ccccc2)cc1,,,,test
US20040009995A1,CS(=O)(=O)CCCCN1C(=O)c2ccccc2C1=O>>CS(=O)(=O)CCCCN,,CCO,,NN,,test
US20080207708A1,CC(C)CI.CCOC(=O)c1csc(Cc2cc(Cl)ccc2O)n1>>CCOC(=O)c1csc(Cc2cc(Cl)ccc2OCC(C)C)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080019915A1,COC(=O)C1(c2ccc(OC)cc2)CC1.COCCl>>COC(=O)C1(c2ccc(OC)c(CCl)c2)CC1,Cl[Ti](Cl)(Cl)Cl,S=C=S,,,,test
US20130165436A1,Cc1cc(N2CCOc3ccc(NCc4ccccc4)c(C)c32)cnc1S(C)(=O)=O>>Cc1cc(N2CCOc3ccc(N)c(C)c32)cnc1S(C)(=O)=O,[Pd],C1CCOC1,CO,CC(=O)O,,test
US20080125468A1,CCC([Mg]Br)C(F)(F)F.CON(C)C(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)nc1>>O=C(CCC(F)(F)F)c1ccc(-c2ccc(C(F)(F)F)cc2)nc1,,C1CCOC1,,,,test
US20140128360A1,CCNCC.CS(=O)(=O)c1cc(F)cc(OCCBr)c1>>CCN(CC)CCOc1cc(F)cc(S(C)(=O)=O)c1,,CCO,,,,test
US20140296272A1,CCCC(C(=O)OC)c1c(C)nc2sc3c(c2c1-c1cccnc1)CCCC3>>CCCC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1cccnc1)CCCC3,,CO,,[Na+].[OH-],,test
US20100210704A1,Cc1cc(F)c(-n2nc(OCC(F)(F)C(F)(F)F)cc2C)cc1SCC(F)(F)F.O=C(OO)c1cccc(Cl)c1>>Cc1cc(F)c(-n2nc(OCC(F)(F)C(F)(F)F)cc2C)cc1S(=O)CC(F)(F)F,,ClC(Cl)Cl,,,,test
US05686424,CC[C@H](C)[C@H](N)C(=O)NCc1ccc(OC)cc1.O=C(O)[C@@H]1CCCN1CC(=O)C12CC3CC(CC(C3)C1)C2>>CC[C@H](C)[C@H](N)C(=O)N(Cc1ccc(OC)cc1)C(=O)[C@@H]1CCCN1CC(=O)C12CC3CC(CC(C3)C1)C2,,ClCCl,,CCN(CC)CC,,test
US20130059849A1,C/C(N)=C/C#N.NNC1CCOCC1>>Cc1cc(N)n(C2CCOCC2)n1,,CCO,,CCN(CC)CC,,test
US20080167307A1,CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCOc2ccc(N3CCN(c4ccccc4)CC3)cc2)cs1>>CC(C)(Sc1nc(CCOc2ccc(N3CCN(c4ccccc4)CC3)cc2)cs1)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060025474A1,CCCCCCCCC(O)(/C=C/c1ccc(C(CC)(CC)c2ccc(O)c(C)c2)cc1C)CC.Cc1ccc(S(=O)(=O)C[C@@H]2CCC(=O)O2)cc1>>CCCC(O)(/C=C/c1ccc(C(CC)(CC)c2ccc(OC[C@@H]3CCC(=O)O3)c(C)c2)cc1C)CC,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120115868A1,COC(=O)c1cc(OCc2c(-c3ccc(F)cc3)nnn2C)no1>>Cn1nnc(-c2ccc(F)cc2)c1COc1cc(C(=O)O)on1,,C1COCCO1,,[Na+].[OH-],,test
US20040077669A1,C#CCOc1cc(Cl)ncn1.Oc1c(F)cccc1F>>C#CCOc1cc(Oc2c(F)cccc2F)ncn1,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20140275016A1,CN(C)C(=O)Nc1cc(Oc2ccc([N+](=O)[O-])nc2)ccn1>>CN(C)C(=O)Nc1cc(Oc2ccc(N)nc2)ccn1,[Zn],CO,,[Cl-].[NH4+],,test
US04479962,Cc1cccc(C)c1NCCNCC(O)COc1cccc(N)c1N.Cl.O=C(Cl)Cl>>Cc1cccc(C)c1NCCNCC(O)COc1cccc2nc[nH]c12.Cl,,O,,Cl,Cl,test
US20130131106A1,Cc1ccc(C=O)cc1OCCI.O=C(O)CCC/C=C\C[C@@H]1[C@@H](CC[C@@H](O)CCc2ccccc2)[C@H](O)C[C@@H]1O>>Cc1ccc(C=O)cc1OCCOC(=O)CCC/C=C\C[C@@H]1[C@@H](CC[C@@H](O)CCc2ccccc2)[C@H](O)C[C@@H]1O,,CCOCC,CN(C)C=O,C1CCC2=NCCCN2CC1,,test
US20070129351A1,CC(C)N1CCN(C(=O)c2ccc(C(O)S(=O)(=O)[O-])cc2)CC1>>CC(C)N1CCN(C(=O)c2ccc(C=O)cc2)CC1,,O,,[Na+].[OH-],,test
US05798442,C=CCO.CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)O>>C=CCOC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C,,ClC(Cl)Cl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20080319005A1,CCOC(=O)C(=O)c1ccc(-n2cnc3cccnc32)cc1>>O=C(O)C(=O)c1ccc(-n2cnc3cccnc32)cc1,,C1CCOC1,,Cl,[Li+].[OH-],test
US20090054435A1,CC(C)[Si](OS(=O)(=O)C(F)(F)F)(C(C)C)C(C)C.Oc1cccc(Br)c1>>CC(C)[Si](Oc1cccc(Br)c1)(C(C)C)C(C)C,,ClCCl,,Cc1cccc(C)n1,,test
US20130310405A1,CC(C)(C)OC(=O)NC1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CCC1.N#Cc1cccc(-c2ccc3c(c2)nn2cc(-c4ccccc4)c(-c4cccc(C#N)c4)nc32)c1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c5ccc(-c6cccc(C#N)c6)cc5nn4cc3-c3ccccc3)cc2)CCC1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20110105544A1,BrCC#Cc1cccc2ccccc12.COC(=O)CCCc1ccc(OCc2ccccc2)cc1>>COC(=O)C(CC#Cc1cccc2ccccc12)CCc1ccc(OCc2ccccc2)cc1,,C1CCOC1,O,Cl,CC(C)[N-]C(C)C.[Li+],test
US20030191118A1,COC(=O)[C@H](Cc1ccc(-c2c(OC)cccc2OC)cc1)NC(=O)c1c(Cl)cc(Br)cc1Cl.C[Si](C)(C)CCOCn1nccc1B(O)O>>COC(=O)[C@H](Cc1ccc(-c2c(OC)cccc2OC)cc1)NC(=O)c1c(Cl)cc(-c2ccnn2COCC[Si](C)(C)C)cc1Cl,,C1CCOC1,,,,test
US20040087798A1,Cc1ncn(-c2ccc(F)c([N+](=O)[O-])c2)c1C>>Cc1ncn(-c2ccc(F)c(N)c2)c1C,[Pd],CO,,,,test
US20080004325A1,COC(=O)CBr.Nc1csc(-c2ccccc2)c1Br>>COC(=O)CNc1csc(-c2ccccc2)c1Br,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20150005311A1,CCOC(=O)CCCCCOC(=O)CCCCCN1CCCc2nc(-c3ccc(C)cc3)c(-c3ccc(C)cc3)nc21>>Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)N(CCCCCC(=O)O)CCC3)cc1,,CO,,[Na+].[OH-],,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(=O)N(C)OC)CC2)c2nc(C)nn12.C[Mg]Br>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(C)=O)CC2)c2nc(C)nn12,,C1CCOC1,,Cl,,test
US03953601,BrBr.c1ccc2c(c1)sc1ccccc12>>Brc1ccc2sc3ccccc3c2c1,,ClC(Cl)Cl,,,,test
US20100137587A1,COCCCCn1c(C(=O)N(CC(C)C)[C@H]2C[C@@H](C(=O)O)CN(C(=O)OC(C)(C)C)C2)nc2ccccc21.Cc1ccccc1S(=O)(=O)Cl.Cc1oc(=O)oc1CO.Cl>>COCCCCn1c(C(=O)N(CC(C)C)[C@@H]2CNC[C@H](C(=O)OCc3oc(=O)oc3C)C2)nc2ccccc21.Cl.Cl,CN(C)c1ccncc1,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20140378431A1,O=[N+]([O-])c1cnc(Cl)nc1Nc1ccc(F)cc1>>Nc1cnc(Cl)nc1Nc1ccc(F)cc1,[Ni],C1CCOC1,,,,test
US20040192686A1,NCCO.[O-][n+]1nc(Cl)nc2ccccc21>>[O-][n+]1nc(NCCO)nc2ccccc21,,COCCOC,,,,test
US20050176761A1,CCOC(=O)C1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccccc2)c1>>O=C(O)C1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccccc2)c1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20110218193A1,COCn1c(=O)c2c(c3cc(OCCN(C)C)ccc31)NCCC2.Cl>>CN(C)CCOc1ccc2[nH]c(=O)c3c(c2c1)NCCC3.Cl,,CCO,,,,test
US20050228004A1,Nc1ncccc1OCc1ccccc1.O=C(CBr)c1ccc(F)cc1>>Fc1ccc(-c2cn3cccc(OCc4ccccc4)c3n2)cc1,,CCO,,,,test
US07067683B2,C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=O.O=C=NS(=O)(=O)Cl>>C[C@]12CC[C@@H]3c4ccc(OS(N)(=O)=O)cc4CC[C@H]3[C@@H]1CCC2=O,,CC(=O)N(C)C,ClCCl,O=CO,,test
US20130116285A1,COc1ncccc1-c1cc(C(N)=O)ccc1Oc1ccccc1.CS(=O)(=O)Cl>>COc1ncccc1-c1cc(C(=O)NS(C)(=O)=O)ccc1Oc1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20090325912A1,CC(=O)O.CCc1cc2c(cc1CC)CC(NC[C@H](O)c1ccc(O)c3[nH]c(=O)ccc13)C2>>CC(=O)O.CCc1cc2c(cc1CC)CC(NC[C@H](O)c1ccc(O)c3[nH]c(=O)ccc13)C2,,CC(C)O,,,,test
US04806549,CC(C)C(=O)Cl.CCOC(=O)C=CNc1ccccc1OC>>CCOC(=O)C(=CNc1ccccc1OC)C(=O)C(C)C,,C1CCOC1,,[H-].[Na+],,test
US20110312903A1,COc1ccc([Mg]Br)cc1.C[Sn](C)(C)Cl>>COc1ccc([Sn](C)(C)C)cc1,,C1CCOC1,,,,test
US06166006,CI.O=C(Nc1ccc(CN2CCCCC2)cc1)C1=Cc2cc(C3CCCCC3)ccc2CC1>>C[N+]1(Cc2ccc(NC(=O)C3=Cc4cc(C5CCCCC5)ccc4CC3)cc2)CCCCC1.[I-],,CN(C)C=O,,,,test
US20060074075A1,Cl.Nc1cccc([N+](=O)[O-])c1.O=N[O-]>>Cl.NNc1cccc([N+](=O)[O-])c1,,Cl,O,Cl[Sn]Cl,,test
US20030158197A1,Cc1cc(C)c(-c2cccc3c(Br)cc(C)nc23)c(C)c1.NCCN>>Cc1cc(C)c(-c2cccc3c(NCCN)cc(C)nc23)c(C)c1,,OCCO,,,,test
US06235900B1,FC(F)(F)c1cc[nH]n1.O=C(c1ccc(F)cc1C(F)(F)F)N1Cc2cccnc2Nc2ccccc21>>O=C(c1ccc(-n2ccc(C(F)(F)F)n2)cc1C(F)(F)F)N1Cc2cccnc2Nc2ccccc21,,CCCCCC,,[H-].[Na+],,test
US05693637,COC(=O)CCNC(=O)c1cc(I)ccc1N.O=C(Br)CBr>>COC(=O)CCNC(=O)c1cc(I)ccc1NC(=O)CBr,,ClCCl,,CCN(CC)CC,,test
US07049312B1,O=C1COc2ccccc2N1.O=Cc1c[nH]c2ccccc12>>O=C1Nc2ccccc2OC1=Cc1c[nH]c2ccccc12,,CN(C)C=O,,C[O-].[Na+],,test
US20130142754A1,C=CC(C)CCC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)OC>>C=CC(C)CCC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)O,,C1CCOC1,O,CO,[Li+].[OH-],test
US20080275054A1,COc1ccc(-n2ncc3c(Cl)ncnc32)cc1.COc1ccc(NC(=O)c2ccc(C)c(N)c2)cc1C(F)(F)F>>COc1ccc(-n2ncc3c(Nc4cc(C(=O)Nc5ccc(OC)c(C(F)(F)F)c5)ccc4C)ncnc32)cc1,,CC(C)(C)O,,,,test
US05506239,COCOC1CCN(CCNCCCCOc2ccc3[nH]c(=O)ccc3c2)CC1.O=S(=O)(Cl)CC1CCCCC1>>COCOC1CCN(CCN(CCCCOc2ccc3[nH]c(=O)ccc3c2)S(=O)(=O)CC2CCCCC2)CC1,,ClCCl,,CCN(CC)CC,,test
US20030045560A1,CCc1oc2ccccc2c1C(=O)N(C)Cc1ccc2c(Br)c(O)ccc2c1.N#CCBr>>CCc1oc2ccccc2c1C(=O)N(C)Cc1ccc2c(Br)c(OCC#N)ccc2c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20110021597A1,CC(C)(C)OC(=O)N1CC[C@H]([C@@H]2CO2)C1.CCO>>CCOC[C@H](O)[C@H]1CCN(C(=O)OC(C)(C)C)C1,,ClCCl,,C,C[O-].[Na+],test
US20050222410A1,C1COCCO1.CC(C)(C)OC(=O)Nc1ccccc1N.CN1CCOCC1.COC1=NN(OC)NC(Cl)=C1>>Nc1ccccc1NC(=O)c1ccc(N2CCOCC2)nc1,,C1COCCO1,O,CN(C)C=O,Cl,test
US20040034017A1,C[Si](C)(C)OC1(C(F)(F)F)c2ccc(O)cc2OC(c2ccc(OCCCCCl)cc2)C1c1ccc(O)cc1>>Oc1ccc(C2C(c3ccc(OCCCCCl)cc3)Oc3cc(O)ccc3C2(O)C(F)(F)F)cc1,,CO,,Cl,,test
US20050080110A1,CCOC(=O)Cl.Nc1c(F)cc(F)cc1Br>>CCOC(=O)Nc1c(F)cc(F)cc1Br,,c1ccncc1,,CCCCCC,CCOC(C)=O,test
US20120321559A1,c1cc(OCCCN2CCCCC2)cc(C2CCCN2)c1.c1ccc(C2CO2)cc1>>OC(CN1CCCC1c1cccc(OCCCN2CCCCC2)c1)c1ccccc1,,CCO,,,,test
US20100069362A1,CN(Cc1ccc(CCN)cc1)C(=O)OC(C)(C)C.COC(=O)c1sc(-c2ccc(Cl)cc2)cc1N=CN(C)C>>CN(Cc1ccc(CCn2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)cc1)C(=O)OC(C)(C)C,,CCOC(C)=O,,CCO,,test
US20150094467A1,CC(=O)NCc1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)cc1NC(C)=O>>CC(C)(C)OC(=O)N1CCN(c2ccc(CN)c(N)c2)CC1,,CCO,,[K+].[OH-],,test
US20070203181A1,O=[N+]([O-])c1ccc(Cl)c(Cl)c1.Sc1ccc(Cl)cc1>>O=[N+]([O-])c1ccc(Sc2ccc(Cl)cc2)c(Cl)c1,,O,,CC(=O)N(C)C,O=C([O-])[O-].[K+].[K+],test
US04900653,CCOC(OCC)OC(C)=O.CS(=O)(=O)Nc1ccc(C(=O)CC#N)cc1>>CCOC=C(C#N)C(=O)c1ccc(NS(C)(=O)=O)cc1,,CC#N,,,,test
US20100197682A1,CCO.Oc1cncc(Br)c1>>CCOc1cncc(Br)c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100168418A1,CCOC(=O)C1(CCCn2c(=O)cnc3ccccc32)CCN(CCSc2cccs2)CC1>>O=C(O)C1(CCCn2c(=O)cnc3ccccc32)CCN(CCSc2cccs2)CC1,,O,,CCO,[Na+].[OH-],test
US20040029859A1,C1CCOC1.CN(C)C=O.[Li]CCCC.c1cnc2[nH]cnc2n1>>O=Cc1ncc2n1CCN(Cc1ccccc1)C2,,O,,O=C([O-])O.[Na+],,test
US04987132,CCOC(=O)N1CCC(C=Cc2ccccc2)CC1>>CCOC(=O)N1CCC(CCc2ccccc2)CC1,[Pd],CCOC(C)=O,,,,test
US20160083400A1,CSC1=N[C@@H](c2ccc(Cl)cc2)CN1.Nn1c(C(=O)O)cnc1C1CCOC1>>O=C1c2cnc(C3CCOC3)n2NC2=N[C@@H](c3ccc(Cl)cc3)CN12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US05208240,CCCn1c(N)c(NC(=O)C(C)Cc2ccc(OCC(=O)OC(C)(C)C)cc2)c(=O)n(CCC)c1=O>>CCCn1c(=O)c2nc(C(C)Cc3ccc(OCC(=O)OCC)cc3)[nH]c2n(CCC)c1=O,,c1ccccc1,,,,test
US20050143422A1,Cc1c(C(=O)OC(C)(C)C)oc2ccc(C=O)c(O)c12>>Cc1c(C(=O)OC(C)(C)C)oc2ccc(CO)c(O)c12,,C1CCOC1,,[BH3-]C#N.[Na+],,test
US20070135477A1,CC(C)(C)N=C=O.Nc1c[nH]nc1-c1nc2ccccc2[nH]1>>CC(C)(C)NC(=O)Nc1c[nH]nc1-c1nc2ccccc2[nH]1,,CN(C)C=O,,,,test
US05075299,O=c1cc(CO)oc(CO)c1O>>Cc1oc(CO)cc(=O)c1O,[Zn],O,,Cl,,test
US20070155729A1,NS(=O)(=O)c1cc(C(=O)OCCCOC(=O)CCC(=O)O)c(NCc2ccco2)cc1Cl.O=C(Cl)C(=O)Cl>>NS(=O)(=O)c1cc(C(=O)OCCCOC(=O)CCC(=O)Cl)c(NCc2ccco2)cc1Cl,,ClCCl,,,,test
US03974161,CCOC(=O)C(=O)OCC.NC(=O)c1cc2c(Cl)cccc2nc1N>>CCOC(=O)c1nc2nc3cccc(Cl)c3cc2c(=O)[nH]1,,CCCCCC,,,,test
US05733914,CN.CSc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1>>CNc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1,,CN(C)C=O,,,,test
US04690951,CC(C)(CCc1ccc(F)cc1)NCC(O)c1cccc(O)c1>>CC(C)(CCc1ccc(F)cc1)NCC(O)c1cccc(O)c1,[Ni],CCO,,Cl,,test
US20100249123A1,CC(C)(C#N)c1ccc(N)cc1-c1cccs1.COc1ccc(C(=O)Cl)cc1OC>>COc1ccc(C(=O)Nc2ccc(C(C)(C)C#N)c(-c3cccs3)c2)cc1OC,,ClCCl,,,,test
US05877193,CC(C)c1ccccc1.O=S(=O)(O)Cl>>CC(C)c1ccc(S(=O)(=O)Cl)cc1,,ClCCl,,[Cl-].[NH4+],,test
US04157399,Cc1ccc(SC(C(=O)N(C)C)c2ccccc2)cc1>>Cc1ccc2sc(-c3ccccc3)c(N(C)C)c2c1,,CCO,,,,test
US20160152626A1,COc1cc2c(cc1Br)-c1c(c(C(=O)N(C)C(C)(C)C)nn1-c1ccsc1)CO2.OB(O)c1cccnc1>>COc1cc2c(cc1-c1cccnc1)-c1c(c(C(=O)N(C)C(C)(C)C)nn1-c1ccsc1)CO2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,CCOCC,O=C([O-])[O-].[K+].[K+],test
US20050070562A1,CCc1c(Cl)ncnc1OC1CCN(C(=O)OC(C)C)CC1.CS(=O)(=O)c1ccc(O)c(F)c1>>CCc1c(Oc2ccc(S(C)(=O)=O)cc2F)ncnc1OC1CCN(C(=O)OC(C)C)CC1,,CS(C)=O,,[H-].[Na+],,test
US20140142126A1,C=O.CC(C)(C)OC(=O)Nc1ncnc2c1c(-c1ccc(Cl)cc1)c(Cl)n2-c1cccc(N)c1>>CNc1cccc(-n2c(Cl)c(-c3ccc(Cl)cc3)c3c(NC(=O)OC(C)(C)C)ncnc32)c1,,C1CCOC1,,[BH3-]C#N.[Na+],,test
US20130217664A1,CI.CN(c1cc2c(cn1)ncn2C)c1ccc(CNS(C)(=O)=O)cc1F>>CN(c1cc2c(cn1)ncn2C)c1ccc(CN(C)S(C)(=O)=O)cc1F,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20150266837A1,CCN(NC(=O)OC(C)(C)C)C(N)=S.CI>>CCN(NC(=O)OC(C)(C)C)C(=N)SC,,CC#N,,,,test
US20070225275A1,COC(=O)C(C)(C)c1ccc(Nc2nc(C(C)C)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1>>CC(C)c1nc2c(c(Nc3ccc(C(C)(C)C(=O)O)cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2,,O,,C1CCOC1,[Li+].[OH-],test
US20090281062A1,O=C(O)c1ccc(Cl)cc1Cl.ON=C1CCCCC1>>O=NC1(OC(=O)c2ccc(Cl)cc2Cl)CCCCC1,,ClCCl,,,,test
US20060205942A1,CC(C)(C)OC(=O)C(N)CCCCNC(=O)OCc1ccccc1.CC(C)(C)OC(=O)ON1C(=O)CCC1=O>>CC(C)(C)OC(=O)NC(CCCCNC(=O)OCc1ccccc1)C(=O)OC(C)(C)C,,CN(C)C=O,,CCN(CC)CC,,test
US20090264416A1,CC(C)(NC(=O)c1cccc(CN2CCNCC2)c1)C(F)(F)F.Nc1ccc(C(=O)O)cc1F>>CC(C)(NC(=O)c1cccc(CN2CCN(C(=O)c3ccc(N)c(F)c3)CC2)c1)C(F)(F)F,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US04441910,CS(=O)(=O)c1sccc1S(N)(=O)=O.O=C(Cl)Cl>>CS(=O)(=O)c1sccc1S(=O)(=O)N=C=O,,Cc1ccccc1C,,C1CN2CCN1CC2,,test
US20080242655A1,CC(C)[Si](OCCCBr)(C(C)C)C(C)C.CCOC(=O)c1[nH]c2ccncc2c1Nc1ccc(I)cc1F>>CCOC(=O)c1c(Nc2ccc(I)cc2F)c2cnccc2n1CCCO[Si](C(C)C)(C(C)C)C(C)C,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04016209,C1COC1.CNCCC[N+](C)(C)C.[Br-]>>CN(CCCO)CCC[N+](C)(C)C.[Br-],,O,,,,test
US06096743,CCOC(=O)CBr.O=c1[nH]c2cc([N+](=O)[O-])c(F)cc2n(O)c1=O>>CCOC(=O)COn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(F)cc21,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US05519139,CCCCOc1ccc(CCNc2ncnc(CC)c2C(=O)O)cc1.CI>>CCCCOc1ccc(CCNc2ncnc(CC)c2C(=O)OC)cc1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150299156A1,CC(=O)Cl.COC(=O)Cc1c(C)cc(C)cc1C>>COC(=O)C(C(C)=O)c1c(C)cc(C)cc1C,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20150105373A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCC(N)c1ccc(O)cc1>>CCC(NC(=O)OC(C)(C)C)c1ccc(O)cc1,,C1CCOC1,,CCN(CC)CC,O,test
US04395406,CSc1nc(=O)[nH]cc1F.O=C(O)CCl>>CSc1nc(=O)n(CC(=O)O)cc1F,,[K+],[OH-],,,test
US20160039811A1,CCOC(=O)C(C)n1ccc(OC)c(C#N)c1=O.O=C1CCC(=O)N1Br>>CCOC(=O)C(C)n1cc(Br)c(OC)c(C#N)c1=O,,CN(C)C=O,,,,test
US20130196974A1,COc1ccc2c(c1)S(=O)(=O)CCN(c1cc(NC(=O)OC(C)(C)C)c3cc(C)ccc3n1)C2>>COc1ccc2c(c1)S(=O)(=O)CCN(c1cc(N)c3cc(C)ccc3n1)C2,,ClCCl,,O=C(O)C(F)(F)F,,test
US04618683,CC(=O)OC(C)=O.COc1ccc2c(c1OC)CC[C@@H]1CNC[C@@H]21>>COc1ccc2c(c1OC)CC[C@@H]1CN(C(C)=O)C[C@@H]21,,c1ccncc1,,Cl,,test
US20130109696A1,COc1ccc(CN(c2nncs2)S(=O)(=O)c2cc(Cl)c(F)cc2F)c(OC)c1.COc1ccc(S)cc1>>COc1ccc(Sc2cc(F)c(S(=O)(=O)N(Cc3ccc(OC)cc3OC)c3nncs3)cc2Cl)cc1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20120283219A1,Cc1ncc(CN)c(N)n1.O=C1CCC(=O)O1>>Cc1ncc(CNC(=O)CCC(=O)O)c(N)n1,,c1ccncc1,,,,test
US20140114068A1,CCCc1ccc(O)cc1.O=C1c2ccccc2C(=O)C1(O)O>>CCCc1ccc2c(c1)C1(O)C(=O)c3ccccc3C1(O)O2,,CC(=O)O,,,,test
US20090137609A1,CC(C)(O[Si](C)(C)C)c1cccc(Br)c1.CCC(CC)(c1ccc(OC[C@H]2CCC(=O)O2)c(C)c1)c1ccc(B2OC(C)(C)C(C)(C)O2)c(C)c1>>CCC(CC)(c1ccc(OC[C@H]2CCC(=O)O2)c(C)c1)c1ccc(-c2cccc(C(C)(C)O[Si](C)(C)C)c2)c(C)c1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US04849450,CCOc1ccc(C2(C(=O)Cl)CC(F)(F)C2(F)F)cc1.OCc1cccc(Oc2ccccc2)n1>>CCOc1ccc(C2(C(=O)OCc3cccc(Oc4ccccc4)n3)CC(F)(F)C2(F)F)cc1,,CCOCC,c1ccccc1,c1ccncc1,,test
US20020042430A1,N#CCCl.Nc1c(Cl)cc(C(=O)OCC2CCNCC2)c2c1OCCO2>>N#CCN1CCC(COC(=O)c2cc(Cl)c(N)c3c2OCCO3)CC1,,CCN(CC)CC,CN(C)C=O,,,test
US20130331372A1,COc1ccc(C2CCC(=O)C(I)C2)cc1.C[O-]>>COC(=O)[C@H]1CC[C@H](c2ccc(OC)cc2)C1,,CCOCC,,O,,test
US20110212945A1,O=[N+]([O-])c1cnc(O)c(I)c1.OB(O)c1ccccc1>>O=[N+]([O-])c1cnc(O)c(-c2ccccc2)c1,,C1COCCO1,O,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],test
US20080255197A1,CC(C)(c1ccc(Cl)cc1)c1cccnc1C=O.Cc1cnc(CNC2CCN(C(=O)OC(C)(C)C)CC2)c(C)c1>>Cc1cnc(CN(Cc2ncccc2C(C)(C)c2ccc(Cl)cc2)C2CCN(C(=O)OC(C)(C)C)CC2)c(C)c1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150274740A1,CCOC(=O)CC(=O)c1ccc2nn[nH]c2c1.COC(=O)c1n[nH]c(N)n1>>COC(=O)c1nc2[nH]c(-c3ccc4nn[nH]c4c3)cc(=O)n2n1,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080188467A1,Cc1cc(C)c(Cl)c([N+](=O)[O-])c1.N#C[Cu]>>Cc1cc(C)c(C#N)c([N+](=O)[O-])c1,,CC(=O)N(C)C,,,,test
US05250547,CC1C(=O)c2cc([N+](=O)[O-])ccc2OC1(C)C>>CC1C(=O)c2cc(N)ccc2OC1(C)C,[Pd],CO,,,,test
US20030130270A1,COC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)O)C1CCCCC1.NCc1ccc2c(N)nccc2c1>>COC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)NCc1ccc2c(N)nccc2c1)C1CCCCC1,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US05200412,CC(=O)NC(C(C)=O)C(C)C.Cl>>CC(=O)C(N)C(C)C.Cl,,CCO,,,,test
US20100256113A1,CO.Cc1c(CO)nc2ccccc2c1OCc1ccccc1.O=C=Nc1ccc2c(c1)CCC2>>Cc1c(OC(=O)N(C)c2ccc3c(c2)CCC3)[nH]c2ccccc2c1=O,[Pd],C1CCOC1,,CCO,,test
US05786367,C=CCOc1ccc2[nH]c(=O)ccc2c1.CC(C)=CCBr>>C=CCOc1ccc2nc(OCC=C(C)C)ccc2c1,,CN(C)C=O,,[H-].[Na+],,test
US05420275,CCOC(=O)c1cc(C)[nH]c(=O)c1C(=O)OCC.O=[N+]([O-])O>>CCOC(=O)c1c([N+](=O)[O-])c(C)[nH]c(=O)c1C(=O)OCC,,CC(=O)OC(C)=O,,O,,test
US03954754,CC(C)=O.NNc1cc2c(nn1)CCN(C(=O)C1CCC1)C2>>CC(C)=NNc1cc2c(nn1)CCN(C(=O)C1CCC1)C2,CC(=O)O,,,,,test
US20030119791A1,COc1ccc(C(=O)Cl)c(OC)c1.Nc1nc2ccccc2s1>>COc1ccc(C(=O)Nc2nc3ccccc3s2)c(OC)c1,,ClCCl,c1ccncc1,Cl,,test
US20090062366A1,CCOC(=O)C1C(=O)NCC1c1ccccc1>>O=C(O)C1C(=O)NCC1c1ccccc1,,CO,,Cl,[Na+].[OH-],test
US20040157814A1,CC(C)[C@@H]1CC(O)OC([C@@H](C)[C@H]2CC(=O)[C@H]3[C@@H]4CCC5CC(O)CC[C@]5(C)[C@H]4CC[C@]23C)C1>>CC(C)[C@@H]1CC(O)OC([C@@H](C)[C@H]2CC(=O)[C@@H]3[C@@H]4CCC5CC(O)CC[C@]5(C)[C@H]4CC[C@]23C)C1,,CO,,[K+].[OH-],,test
US20020156053A1,CCOC(C)(OCC)P(=O)(OCC)C(F)C(O)CNC(=O)OC(C)(C)C>>NCC(O)C(F)[PH](=O)O,,CO,,Cl,,test
US20100137299A1,COCCOCCBr.COc1ccc(OC)c2c1NC(=O)C2=O>>COCCOCCN1C(=O)C(=O)c2c(OC)ccc(OC)c21,,C1CCOC1,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120178715A1,C[Si](C)(C)CCOCn1cnc(-c2ccc(-c3cnn4ccc(N5C(=O)OC[C@@H]5c5ccccc5)nc34)cc2F)n1>>O=C1OC[C@H](c2ccccc2)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1,,O=C(O)C(F)(F)F,,,,test
US20030195193A1,CCOC(=O)c1ccc(CBr)c([N+](=O)[O-])c1.C[N+]1([O-])CCOCC1>>CCOC(=O)c1ccc(C=O)c([N+](=O)[O-])c1,,CC#N,,,,test
US03944675,Nc1ccc(F)c(F)c1.O=C(Cl)C12CC3CC(CC(C3)C1)C2>>O=C(Nc1ccc(F)c(F)c1)C12CC3CC(CC(C3)C1)C2,,CCOCC,,CCN(CC)CC,,test
US20060142265A1,OCc1ccc2[nH]cnc2c1>>O=Cc1ccc2[nH]cnc2c1,O=[Mn]=O,c1ccccc1,,,,test
US04031226,O=C(c1ccc(F)cc1[N+](=O)[O-])N1CC1.OC1(c2ccc(Cl)cc2)CCNCC1>>O=C(NCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1[N+](=O)[O-],,CO,,c1ccccc1,,test
US20100197683A1,CCC(C)=O.COCc1nnc(N)[nH]1>>CCC(C)Nc1nnc(COC)[nH]1,,CC(=O)O,,O,[BH3-]C#N.[Na+],test
US06500853B1,COC(=O)c1ccc(S(=O)(=O)CCc2c(CO[Si](C)(C)C(C)(C)C)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1>>COC(=O)c1ccc(S(=O)(=O)CCc2c(CO)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130310331A1,CCOC(=O)/C(=C/c1ccccc1F)O[C@H]1O[C@@H](COC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>O=C(O)/C(=C/c1ccccc1F)O[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O,,C1CCOC1,O,[Li]O,,test
US04692447,CC(=O)Cl.c1ccc2c(c1)CCC2>>CC(=O)c1ccc2c(c1)CCC2,,c1ccccc1,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20150065522A1,C#Cc1ccccn1.CCc1c(C)[nH]c2c(/C(Cl)=N/O)cnn2c1=O>>CCc1c(C)[nH]c2c(-c3cc(-c4ccccn4)on3)cnn2c1=O,,CCOC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150158873A1,BrCC1CC1.CCOc1cc(=O)n(C)cc1-c1cc(NS(=O)(=O)CC)ccc1Oc1ccc(F)cc1F>>CCOc1cc(=O)n(C)cc1-c1cc(N(CC2CC2)S(=O)(=O)CC)ccc1Oc1ccc(F)cc1F,,CN(C)C=O,,O,[H-].[Na+],test
US05387685,BrCCCCCBr.COc1ccc(CSc2ccc(C)cc2)cc1OC>>COc1ccc(C(CCCCCBr)Sc2ccc(C)cc2)cc1OC,,C1CCOC1,,[Li]C(C)(C)C,,test
US20030144297A1,COC(=O)c1nc(N[C@@H]2c3ccccc3C[C@@H]2O)cnc1Br.OB(O)c1ccc(Cl)cc1Cl>>COC(=O)c1nc(N[C@@H]2c3ccccc3C[C@@H]2O)cnc1-c1ccc(Cl)cc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20040063775A1,CCOC(=O)Cc1cn(Cc2ccccc2)nc1O.Cc1oc(-c2ccccc2)nc1COc1ccc(CCl)cn1>>CCOC(=O)Cc1cn(Cc2ccccc2)nc1OCc1ccc(OCc2nc(-c3ccccc3)oc2C)nc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20060258714A1,[N-]=[N+]=NC[C@H]1CCc2cc(F)cc(-c3c(Cl)cccc3Cl)c2O1>>NC[C@H]1CCc2cc(F)cc(-c3c(Cl)cccc3Cl)c2O1,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20160075710A1,BrCc1ccccc1.O=c1cc(I)cn[nH]1>>O=c1cc(I)cnn1Cc1ccccc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20120220566A1,COC=C(C(=O)OC)c1ccc(CN(CCCNC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc1.Nc1ncc(-c2ccc(Br)cc2)[nH]1>>CC(C)(C)OC(=O)NCCCN(Cc1ccc(-c2cn3cc(-c4ccc(Br)cc4)[nH]c3nc2=O)cc1)C(=O)OC(C)(C)C,,CCO,,C[O-].[Na+],,test
US04036986,CCC(C)NCc1ccc(Cl)cc1.S=C=Nc1ccccc1>>CCC(C)N(Cc1ccc(Cl)cc1)C(=S)Nc1ccccc1,,CCOCC,,,,test
US20110311474A1,CC1CC(NS(=O)(=O)C2CC2)CC1N=C=O>>CC1CC(NS(=O)(=O)C2CC2)CC1N,,C1CCOC1,,[Li+].[OH-],,test
US04226876,CN=C=S.Cc1cccc(OCC2=NCCN2)c1C>>CNC(=S)N1CCN=C1COc1cccc(C)c1C,,ClC(Cl)Cl,,,,test
US20070197614A1,Cc1cccc(CBr)c1C(=O)Br.OCc1ccccc1>>Cc1cccc(CBr)c1C(=O)OCc1ccccc1,,COC(C)(C)C,,,,test
US04402729,CC(Oc1cc(Oc2ccc(Br)cc2[N+](=O)[O-])ccc1[N+](=O)[O-])C(=O)Cl.CCNCC1OC(C)C(C)O1>>CCN(CC1OC(C)C(C)O1)C(=O)C(C)Oc1cc(Oc2ccc(Br)cc2[N+](=O)[O-])ccc1[N+](=O)[O-],,ClCCl,,,,test
US04420424,CC(=O)O.COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CCCCN)NC(=O)OCc1ccccc1)C(C)C>>CC(=O)O.COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](N)CCCCN)C(C)C,,CC(=O)O,,,,test
US20140113915A1,Nc1cncc(-c2ccc3ncnc(OC4CCOCC4)c3n2)c1.O=S(=O)(Cl)c1ccc(F)cc1Br>>O=S(=O)(Nc1cncc(-c2ccc3ncnc(OC4CCOCC4)c3n2)c1)c1ccc(F)cc1Br,,ClCCl,c1ccncc1,,,test
US20070244131A1,COc1cccc(-c2cc(Cl)nc(OC)n2)c1.NCCc1ccc([N+](=O)[O-])cc1>>COc1cccc(-c2cc(NCCc3ccc([N+](=O)[O-])cc3)nc(OC)n2)c1,,CCO,,CCN(C(C)C)C(C)C,Cl,test
US20100311749A1,Cc1ccc(Br)cc1NC(=O)CN(CCOS(C)(=O)=O)C(=O)OC(C)(C)C.Cc1ccccc1N1CCN(C(=O)OC(C)(C)C)CC1=O>>Cc1ccc(Br)cc1N1CCN(C(=O)OC(C)(C)C)CC1=O,,CN(C)C=O,,CO,[H-].[Na+],test
US20060205794A1,CC(=O)O.CC1(C)OCc2cc([C@@H](O)CNCCCCCCOCCCCc3cccc(S(=O)(=O)C4CCCC4)c3)ccc2O1>>CC(=O)Oc1ccc([C@@H](O)CNCCCCCCOCCCCc2cccc(S(=O)(=O)C3CCCC3)c2)cc1CO,,O,,,,test
US20100305131A1,CCOC(=O)C[C@H](N)Cc1ccc(-c2cc(Cl)ccc2F)cc1.O=C1CCC(=O)O1>>CCOC(=O)C[C@@H](Cc1ccc(-c2cc(Cl)ccc2F)cc1)NC(=O)CCC(=O)O,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20040157909A1,C1CNC[C@H](CN2CCCC2)C1.Cc1c(C(=O)O)c[nH]c1/C=C1\C(=O)Nc2cccc(-c3c(F)cccc3F)c21>>Cc1c(C(=O)N2CCC[C@@H](CN3CCCC3)C2)c[nH]c1/C=C1\C(=O)Nc2cccc(-c3c(F)cccc3F)c21,,C1CCOC1,,ClCCCl,On1nnc2ccccc21,test
US20110263593A1,Brc1cnc2nccn2c1.OB(O)c1cccc(F)c1>>Fc1cccc(-c2cnc3nccn3c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20060084680A1,CCOC(=O)C[C@@H]1CCc2cc(OCCCOc3ccc(C#N)cn3)ccc21.S>>CCOC(=O)C[C@@H]1CCc2cc(OCCCOc3ccc(C(N)=S)cn3)ccc21,,CN(C)C=O,,CCNCC,,test
US04509970,CCP(=O)(Cl)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].COC(=O)C(=NO)c1ccccc1>>CCP(=O)(ON=C(C(=O)OC)c1ccccc1)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-],,ClCCl,,,,test
US20150065705A1,Cc1ccc(S(=O)(=O)OS(=O)(=O)c2ccc(C)cc2)cc1.O=c1nc(N2CCN(c3ccc(F)cc3)CC2)ncn1CO>>Cc1ccc(S(=O)(=O)OCn2cnc(N3CCN(c4ccc(F)cc4)CC3)nc2=O)cc1,,ClCCl,,CCN(CC)CC,,test
US20090298807A1,CCOC(CBr)OCC.OCc1cccc(O)c1>>CCOC(COc1cccc(CO)c1)OCC,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080305977A1,CCC/C=C\CC(C)CCOC(C)=O>>CCC/C=C\CC(C)CCO,,CCO,O,[Na+].[OH-],,test
US20120309966A1,NCc1nccnc1Cl.O=C(Cl)C1CN(C(=O)OCc2ccccc2)C1>>O=C(NCc1nccnc1Cl)C1CN(C(=O)OCc2ccccc2)C1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20030073847A1,COCOc1c(C)cc(O)cc1Cl.ClCC=C(Cl)Cl>>COCOc1c(C)cc(OCC=C(Cl)Cl)cc1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030069297A1,COc1cccc(-c2cccc3c2CC(=O)N3)c1.Cc1[nH]c(C=O)c(C)c1C(=O)NCCN(C(C)C)C(C)C>>COc1cccc(-c2cccc3c2C(=Cc2[nH]c(C)c(C(=O)NCCN(C(C)C)C(C)C)c2C)C(=O)N3)c1,C1CCNCC1,CCO,,,,test
US20080139561A1,CC(C)Oc1cc(N)n[nH]1.O=[N+]([O-])c1cc(Cl)c(Cl)nc1Cl>>CC(C)Oc1cc(Nc2nc(Cl)c([N+](=O)[O-])cc2Cl)n[nH]1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090176786A1,CN(C(=O)c1c(F)cccc1F)C(=O)N(C)c1ccc(SC(F)(F)C(F)F)cc1F.O=C(OO)c1cccc(Cl)c1>>CN(C(=O)c1c(F)cccc1F)C(=O)N(C)c1ccc(S(=O)C(F)(F)C(F)F)cc1F,,ClC(Cl)Cl,,,,test
US20080312248A1,CC(=O)OC(C)=O.COc1cc(N)cc(C(F)(F)F)c1>>COc1cc(NC(C)=O)cc(C(F)(F)F)c1,,Cc1ccccc1,,CCCCCC,,test
US20100298140A1,CCc1ccsc1.CN(C)C=O>>CCc1csc(C=O)c1,,CCOCC,,CCCCCC,[Li]CCCC,test
US04735959,CCCC(c1ccccc1N1CCCCC1)C(C(N)=O)c1ccc(C(=O)OCC)cc1>>CCCC(c1ccccc1N1CCCCC1)C(C(N)=O)c1ccc(CO)cc1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20130315825A1,CC(=O)Nc1ccccc1Sc1ccc([N+](=O)[O-])cc1[N+](=O)[O-].ClI>>CC(=O)Nc1cc(I)ccc1Sc1ccc([N+](=O)[O-])cc1[N+](=O)[O-],,CC(=O)O,,,,test
US20040220191A1,CCCCBr.COC(=O)c1ccc2[nH]ccc2c1>>CCCCn1ccc2cc(C(=O)O)ccc21,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20030220348A1,COc1cnc(CCl)c(Cl)n1.Fc1cccc(-c2ncc[nH]2)n1>>COc1cnc(Cn2ccnc2-c2cccc(F)n2)c(Cl)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050131014A1,CCOC(=O)C(=O)c1ccc(C#N)cc1.O=CO>>CCOC(=O)C(O)c1ccc(C=O)cc1,[Ni],,,,,test
US20090124596A1,O=C(O)c1cn2c(n1)CCCC2>>OCc1cn2c(n1)CCCC2,,C1CCOC1,,CO,,test
US20120040998A1,C[C@@H]1CC[C@@H](C(N)=O)CN1C(=O)OC(C)(C)C>>C[C@@H]1CC[C@H](C#N)CN1C(=O)OC(C)(C)C,,ClCCl,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US20040024021A1,CCCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C.Cl>>CCCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C.Cl,,CC(C)O,,,,test
US05169852,CC(=O)OC(C)=O.c1ccc2c3c([nH]c2c1)CNCC3>>CC(=O)N1CCc2c([nH]c3ccccc23)C1,,CCOC(C)=O,c1ccncc1,,,test
US20050043354A1,Cc1cc(F)ccc1C1CC(=O)C=CN1C(=O)OCc1ccccc1>>Cc1cc(F)ccc1C1CC(=O)CCN1C(=O)OCc1ccccc1,[Zn],CC(=O)O,,,,test
US20130059846A1,COCCBr.Cc1nc(-c2ccc3ncc(C(=O)Nc4cc(-c5noc(C6CC(F)(F)C6)n5)ccc4C)n3c2)n[nH]1>>COCCn1nc(-c2ccc3ncc(C(=O)Nc4cc(-c5noc(C6CC(F)(F)C6)n5)ccc4C)n3c2)nc1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04456716,Cc1cc(S)cc(C(C)(C)C)c1O.O=C1C=CC(=O)N1c1ccccc1>>Cc1cc(SC2CC(=O)N(c3ccccc3)C2=O)cc(C(C)(C)C)c1O,,CCN(CC)CC,,,,test
US20060160803A1,CC(=O)OC(C)=O.COC(=O)CCc1cccc(Oc2ccnc(N)c2)c1>>COC(=O)CCc1cccc(Oc2ccnc(NC(C)=O)c2)c1,,c1ccncc1,,,,test
US05958954,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2ccc(CC)cc2)=CC(C)(C)S3)nc1>>CCc1ccc(C2=CC(C)(C)Sc3ccc(CCc4ccc(C(=O)O)cn4)cc32)cc1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US04476307,CC(=O)Nc1ccc(F)cc1.Fc1ccc(Br)cc1>>Fc1ccc(Nc2ccc(F)cc2)cc1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20100056553A1,O=C(NC1CCC2CC1CCC21OCCO1)OCc1ccccc1>>O=C(NC1CCC2CC1CCC2=O)OCc1ccccc1,,CC(C)=O,,Cl,,test
US09365557B2,CN(C)C(=O)c1ccc(-c2cnc(N)c(C(=O)NN)n2)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CN(C)C(=O)c1ccc(-c2cnc(N)c(-c3n[nH]c(=O)o3)n2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100120761A1,COCCBr.Oc1cccc(Br)c1>>COCCOc1cccc(Br)c1,,CCOCC,CO,O=C([O-])[O-].[K+].[K+],,test
US20020188009A1,CCOC(=O)CCCCCCn1c(C)nc(-c2ccc(F)cc2)c1-c1ccc(F)cc1>>Cc1nc(-c2ccc(F)cc2)c(-c2ccc(F)cc2)n1CCCCCCC(=O)O,,CCO,CCOC(C)=O,[Na+].[OH-],,test
US04718934,CC(=O)OC(C)=O.Clc1ccc(CNc2cncnc2)c(Cl)c1>>CC(=O)N(Cc1ccc(Cl)cc1Cl)c1cncnc1,O=S(=O)(O)O,CC(=O)O,,ClC(Cl)Cl,,test
US20150065507A1,Cc1nc(C2CCN(Cc3ccccc3)C2)ccc1N.Cc1noc(C)c1COc1ccc(S(=O)(=O)Cl)cc1>>Cc1nc(C2CCN(Cc3ccccc3)C2)ccc1NS(=O)(=O)c1ccc(OCc2c(C)noc2C)cc1,,ClCCl,,c1ccncc1,,test
US20100323994A1,CC(C)n1ccc(Nc2cc(Cl)nn3c(C(=O)Nc4ccncc4F)cnc23)n1.N[C@H]1CC[C@H](O)CC1>>CC(C)n1ccc(Nc2cc(N[C@@H]3CC[C@@H](O)CC3)nn3c(C(=O)Nc4ccncc4F)cnc23)n1,,CO,,,,test
US04804661,CN(C)c1ccc(C(=O)Cl)cc1.Clc1ccc(CCN2CCNCC2)cc1>>CN(C)c1ccc(C(=O)N2CCN(CCc3ccc(Cl)cc3)CC2)cc1,,ClCCl,,CCN(CC)CC,[Na+].[OH-],test
US20110021573A1,COC(=O)Cc1ccc(OS(=O)(=O)C(F)(F)F)c(-c2ccc(C(F)(F)F)cc2CN2C(=O)O[C@H](c3ccccc3)[C@@H]2C)c1.OB(O)c1ccccc1>>C[C@H]1[C@@H](c2ccccc2)OC(=O)N1Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1-c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20080015255A1,CCCCCCCCSC#N.O=S(=O)(Cl)Cl>>CCCCCCCCS(=O)(=O)Cl,,O,,CC(=O)O,,test
US20050250836A1,Cn1cccc1C=CC(=O)OCc1ccccc1.O=C1C=CC(=O)N1>>Cn1ccc2c1CC(C(=O)OCc1ccccc1)C1C(=O)NC(=O)C21,,CCOCC,,,,test
US20040127574A1,O=C1NC(Cc2cccc(OC(F)(F)F)c2)C(c2ccc(F)cc2)O1>>NC(Cc1cccc(OC(F)(F)F)c1)C(O)c1ccc(F)cc1,,CCO,O,[Na+].[OH-],,test
US20100256092A1,COC(=O)c1cccc(Oc2ccc3c(c2)B(O)OC3)c1>>OCc1cccc(Oc2ccc3c(c2)B(O)OC3)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20160060273A1,CCOc1cc(CO)cc(C2CC2)c1I>>CCOc1cc(C=O)cc(C2CC2)c1I,,O,,CCN(CC)CC,CS(C)=O,test
US20140031360A1,CC(C)(C)OC(=O)N1CCC[C@@H](Nc2cncc(-c3nn(C4CCCCO4)c4ccc(-c5cncc(C6CC6)n5)cc34)n2)C1>>c1cc2[nH]nc(-c3cncc(N[C@@H]4CCCNC4)n3)c2cc1-c1cncc(C2CC2)n1,,CO,,Cl,,test
US20070105904A1,Nc1ncccc1-c1cnn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c1>>Nc1ncccc1-c1cn[nH]c1,,C1CCOC1,,CO,Cl,test
US20060135578A1,CCOC(=O)c1cn(Cc2ccccc2)nc1O.COc1cc(CCl)ccc1OCc1nc(-c2ccco2)oc1C>>CCOC(=O)c1cn(Cc2ccccc2)nc1OCc1ccc(OCc2nc(-c3ccco3)oc2C)c(OC)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20070249722A1,NC(CO)C(C(F)(F)F)C(F)(F)F.O=S(=O)(Cl)c1ccc(F)cc1>>O=S(=O)(NC(CO)C(C(F)(F)F)C(F)(F)F)c1ccc(F)cc1,,ClCCl,,CCN(CC)CC,,test
US20020111274A1,COS(=O)(=O)OC.COc1ccccc1-n1nnc2cc(F)c(-n3c(=O)cc(C(F)(F)F)[nH]c3=O)cc21>>COc1ccccc1-n1nnc2cc(F)c(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)cc21,,C1CCOC1,,O,O=C([O-])[O-].[K+].[K+],test
US20100216746A1,C[Si](C)(C)CCOCn1cnc(Cl)c1C(=O)NCc1ccc(Cl)c(Oc2cc(C#N)cc(C(F)F)c2)c1F>>N#Cc1cc(Oc2c(Cl)ccc(CNC(=O)c3[nH]cnc3Cl)c2F)cc(C(F)F)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160272651A1,CCOC(=O)CN1CCN(c2ccc(N(CCO[Si](C)(C)C(C)(C)C)C(=O)c3c(Cl)ncnc3Cl)cc2Cl)C1=O>>CCOC(=O)CN1CCN(c2ccc(N(CCO)C(=O)c3c(Cl)ncnc3Cl)cc2Cl)C1=O,,CCO,,Cl,O,test
US20030059397A1,CCCC(C)C1(CC)C(=O)[N-]C(=O)NC1=O>>CCCC(C)C1(CC)C(=O)NC(=O)NC1=O,,O,,[Cl-].[Na+],,test
US20100190787A1,C1CCNCC1.O=[N+]([O-])c1ccc(C2CO2)cc1>>O=[N+]([O-])c1ccc(C(O)CN2CCCCC2)cc1,,CCO,ClCCl,CO,,test
US04733002,NCc1ccccc1.O=C(O)/C=C/c1ccc(O)c(O)c1>>O=C(/C=C/c1ccc(O)c(O)c1)NCc1ccccc1,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20040254212A1,CCOC(=O)C1CCC(c2cc3cccnc3c(-c3cccc(OC(F)(F)F)c3)n2)CC1>>O=C(O)C1CCC(c2cc3cccnc3c(-c3cccc(OC(F)(F)F)c3)n2)CC1,,CCO,O,Cl,[K+].[OH-],test
US20160244409A1,CC(C)CN1C=CC(C)(C)CC1.O=C1CCC(=O)O1>>CC(C)CN1C=C(C(=O)CCC(=O)O)C(C)(C)CC1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100216746A1,CCCC(=O)C(=O)OCC.NNc1ccccc1>>CCOC(=O)c1[nH]c2ccccc2c1CC,,CCO,,,,test
US20130210831A1,CC(C)(C)OC(=O)N[C@@H]1CCN(c2ncnc3c2ccn3COCC[Si](C)(C)C)C1.N#Cc1ccc(Cl)nc1>>C[Si](C)(C)CCOCn1ccc2c(N3CC[C@@H](Nc4ccc(C#N)cn4)C3)ncnc21,,Cl,O,CCN(C(C)C)C(C)C,,test
US05596097,COC(=O)c1cncc(O)c1C(=O)c1cc(Cl)ccc1F>>O=C(O)c1cncc(O)c1C(=O)c1cc(Cl)ccc1F,,CO,O,Cl,[Na+].[OH-],test
US20090036445A1,CC(C)(C)Cn1c(N)nc2ccc(-c3nc(C(C)(C)C)[nH]c3-c3ccc(F)cc3F)nc21.CS(=O)(=O)O>>CC(C)(C)Cn1c(N)nc2ccc(-c3nc(C(C)(C)C)[nH]c3-c3ccc(F)cc3F)nc21.CS(=O)(=O)O,,CO,,,,test
US20030083333A1,CNC(=O)c1cc(C(C)(C)C)cc(N)c1OC.Nc1ccc(Oc2ccncc2)c2ccccc12.O=C(Cl)Cl>>CNC(=O)c1cc(C(C)(C)C)cc(NC(=O)Nc2ccc(Oc3ccncc3)c3ccccc23)c1OC,,ClCCl,,O=C([O-])O.[Na+],,test
US20020119985A1,CC(=O)OC(C)=O.CC(C)[C@H](NC(=O)OCc1ccccc1)C(O)C(=O)O>>CC(=O)OC(C(=O)O)[C@@H](NC(=O)OCc1ccccc1)C(C)C,,CCOC(C)=O,,c1ccncc1,,test
US20160009744A1,Cc1sc(CO[Si](C)(C)C(C)(C)C)cc1Cc1cccc(Cl)c1>>Cc1sc(CO)cc1Cc1cccc(Cl)c1,,CCO,,Cl,O=C([O-])O.[Na+],test
US06534546B1,CC(C)(C)OC(=O)NC(C)(C)c1cccc(NC(N)=S)c1.CI>>CSC(=N)Nc1cccc(C(C)(C)NC(=O)OC(C)(C)C)c1.I,,CC#N,,,,test
US20140073625A1,BrCc1ccccc1.CC(C)(C)OC(=O)N1CC(O)C1>>CC(C)(C)OC(=O)N1CC(OCc2ccccc2)C1,,CN(C)C=O,,[H-].[Na+],,test
US20100130492A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNc1ncc(-c2nc(N3CCOCC3)c3ncn(CC4CCOC4)c3n2)cn1>>CN(C(=O)OC(C)(C)C)c1ncc(-c2nc(N3CCOCC3)c3ncn(CC4CCOC4)c3n2)cn1,CN(C)c1ccncc1,CN(C)C=O,,,,test
US20130079324A1,CC(C)(C)OC(=O)N[C@@H]1CCCNC1.Cn1cc(Nc2nc(Cl)c3c(Cl)c[nH]c3n2)cn1>>Cn1cc(Nc2nc(N3CCCC(NC(=O)OC(C)(C)C)C3)c3c(Cl)c[nH]c3n2)cn1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20100204265A1,N[C@@H]1CCN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)C1.O=C(O)CCCl>>O=C(CCCl)N[C@@H]1CCN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)C1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05824691,CCOC=C(C#N)C(=O)OCC.NNc1cccc(C(=O)O)c1>>CCOC(=O)c1cnn(-c2cccc(C(=O)O)c2)c1N,,CCO,,,,test
US20090042929A1,CC1(C(=O)O)CCCCC1.CNCc1cccs1>>CN(Cc1cccs1)C(=O)C1(C)CCCCC1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US04009273,BrBr.O=C1Cc2ccccc2Cc2ccccc21>>O=C1c2ccccc2Cc2ccccc2C1Br,,ClC(Cl)(Cl)Cl,,,,test
US05344837,CN(C)C=O.N#Cc1ccc(CCCCC(=O)O)cc1>>N#Cc1ccc(CCCCCN)cc1,,ClCCCl,,O=C(Cl)C(=O)Cl,,test
US07074801B1,CCOC(=O)c1ccc(-c2ncnc3ccc(-c4cnn(C(c5ccccc5)(c5ccccc5)c5ccccc5)c4)cc23)cc1F>>O=C(O)c1ccc(-c2ncnc3ccc(-c4cnn(C(c5ccccc5)(c5ccccc5)c5ccccc5)c4)cc23)cc1F,,CCO,O,[Li+].[OH-],,test
US03954794,CC(=O)CCC1C(=O)C(C(C)C)CCC1C.NO>>Cc1ccc2c(n1)C(C(C)C)CCC2C,,CCO,,Cl,,test
US20130109678A1,CN(C)C(=O)Cl.Nc1cc(N2CCNCC2)ccc1[N+](=O)[O-]>>CN(C)C(=O)N1CCN(c2ccc([N+](=O)[O-])c(N)c2)CC1,,CN(C)C=O,,CCN(CC)CC,O,test
US04816452,CCOC(=O)/C(=N\O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1.O[C@H]1CC[C@H](Cl)CC1>>CCOC(=O)/C(=N\O[C@@H]1CC[C@H](Cl)CC1)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,c1ccccc1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090163508A1,CC(C)(C)OC(=O)N1CCN(c2cncc(-c3ccc(F)cc3F)c2)CC1>>Fc1ccc(-c2cncc(N3CCNCC3)c2)c(F)c1,,CCOC(C)=O,,Cl,,test
US20130296554A1,C1C[C@H]2COC[C@@H](C1)N2.C=C(C)[C@@H]1CC[C@]2(NCCCl)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NCCN3[C@H]4CCC[C@@H]3COC4)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US20150307450A1,CN(C)c1ccncc1/C=C(\C#N)c1c[nH]c2ccc(Cl)cc12.Cl>>CN(C)c1ccncc1/C=C(\C#N)c1c[nH]c2ccc(Cl)cc12.Cl,,CCO,,ClCCl,O,test
US04082751,CCCOc1ccccc1C(N)=O.CCOC=C(C#N)C(=O)OCC.[N-]=[N+]=[N-].[NH4+]>>CCCOc1ccccc1-c1ncc(-c2nnn[nH]2)c(=O)[nH]1,,CN(C)C=O,,[Cl-].[Na+],,test
US20120129856A1,CCOC(=O)C(C)(C)CCCCCC(c1ccccc1Cl)N1CCc2occc2C1>>CC(C)(CCCCCC(c1ccccc1Cl)N1CCc2occc2C1)C(=O)O,,O,,CCO,[Na+].[OH-],test
US20160122344A1,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(C#N)cc1CC2C(C)(C)COC>>COCC(C)(C)C1Cc2cc(C#N)c(OC)cc2-c2cc(=O)c(C(=O)O)cn21,,C1CCOC1,,[Li+].[OH-],,test
US20150031685A1,CI.COC(=O)Cc1ccc2oc(=O)[nH]c2c1>>COC(=O)Cc1ccc2oc(=O)n(C)c2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05455260,Cc1ccc(C#CCOCCNCCOCc2ccc(-c3nc4ccccc4o3)cc2)cc1.Cl>>Cc1ccc(CCCOCCNCCOCc2ccc(-c3nc4ccccc4o3)cc2)cc1.Cl,[Pd],CO,,,,test
US06011028,COC1=NC(Cc2ccco2)CCCC1.[Cl-].[NH4+]>>Cl.N=C1CCCCC(Cc2ccco2)N1,,CO,,,,test
US20110053959A1,CCN(CC)S(F)(F)F.C[C@@H]1C[C@@H](O)c2ncnc(N3CC4(CCN(C(=O)OC(C)(C)C)CC4)c4cc(Cl)ccc43)c21>>C[C@@H]1C[C@H](F)c2ncnc(N3CC4(CCN(C(=O)OC(C)(C)C)CC4)c4cc(Cl)ccc43)c21,,ClCCl,,,,test
US20060148806A1,CCOC(=O)CC(=O)c1cc(F)c(F)cc1F.COC1=NCCC1>>CCOC(=O)C(C(=O)c1cc(F)c(F)cc1F)=C1CCCN1,,CCN(CC)CC,,,,test
US20100137613A1,CCCCc1ncc(C=O)n1Cc1ccc(C(=O)OC)cc1.CCOC(=O)C(Cc1cccs1)C(=O)O>>CCCCc1ncc(C=C(Cc2cccs2)C(=O)O)n1Cc1ccc(C(=O)O)cc1,,C1CCCCC1,,,,test
US20100233116A1,Cc1cc(N2CCN(CC(=O)c3ccccc3)C2=O)sc1C(=O)NCc1cccnc1>>Cc1cc(N2CCN(CC(O)c3ccccc3)C2=O)sc1C(=O)NCc1cccnc1,,CO,ClC(Cl)Cl,[BH4-].[Na+],,test
US20160200708A1,CN=CC(OC)OC.C[Si](C)(C)C(F)(F)F>>CNC(C(OC)OC)C(F)(F)F,,CC#N,CN(C)C=O,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20090143228A1,COC(=O)c1cc(Cl)cc(Cl)c1N.NOCCO>>Nc1c(Cl)cc(Cl)cc1C(=O)NOCCO,,CO,O,Cl,C[O-].[Na+],test
US20060041123A1,COc1ccc2ncc(F)c(CCN3CC[C@H](NC(=O)OC(C)(C)C)[C@H](O)C3)c2n1>>COc1ccc2ncc(F)c(CCN3CC[C@H](N)[C@H](O)C3)c2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05006522,BrCCCCCCN1CCCCC1.O=C1c2ccccc2Nc2ncccc2N1Cc1ccccc1>>O=C1Nc2cccnc2N(CCCCCCN2CCCCC2)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20090023707A1,ClCc1coc(-c2ccc(Cn3cnc4ccccc43)cc2)n1.O=C1CCC(=O)N1Br>>ClCc1nc(-c2ccc(Cn3cnc4ccccc43)cc2)oc1Br,,ClC(Cl)Cl,,,,test
US20160145247A1,COC(=O)c1cc(Br)cc(OC[C@H]2CCCO2)c1>>OCc1cc(Br)cc(OC[C@H]2CCCO2)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080207891A1,CC(=O)OC[C@H]1O[C@@H](n2cnc3c(-n4ccnc4C(C)C)nc(Cl)nc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O>>CC(C)c1nccn1-c1nc(Cl)nc2nc[nH]c12,,CC(=O)O,,CC(=O)Cl,,test
US20110166121A1,COC(CC#N)OC.NO>>COC(CC(=N)NO)OC,,CO,,Cl,O=C([O-])O.[Na+],test
US20150065550A1,CC[C@@H]1CO1.CCc1ccccc1Br.[Li]CCCC>>CCC[C@@H](O)c1ccccc1CC,,C1CCOC1,,,,test
US20110105578A1,CCCCc1nc(-c2ccc(OC[C@@H]3CO3)cc2)cn1-c1ccc(Oc2ccc(Cl)cc2)cc1.CNC>>CCCCc1nc(-c2ccc(OC[C@@H](O)CN(C)C)cc2)cn1-c1ccc(Oc2ccc(Cl)cc2)cc1,,C1CCOC1,,,,test
US04923872,CCOC(=O)C(C#N)(Cc1ccccc1)c1nc(N)[nH]c(=O)c1[N+](=O)[O-]>>N#CC(Cc1ccccc1)c1nc(N)[nH]c(=O)c1[N+](=O)[O-],,[Na+],[OH-],Cl,,test
US20100076197A1,Cc1c(C(=O)O)n[nH]c1-c1ccc(Cl)cc1Cl.O=S(Cl)Cl>>Cc1c(C(=O)Cl)n[nH]c1-c1ccc(Cl)cc1Cl,,Cc1ccccc1,,CN(C)C=O,,test
US20100063294A1,O=C1OCc2ccccc21>>OCc1ccccc1CO,,C1CCOC1,,[H][H],,test
US20120101083A1,CCOc1ccc(-c2nc(-c3ccc4c(c3)CCN(C(=O)CNC(=O)OC(C)(C)C)CC4)no2)cc1C#N>>CCOc1ccc(-c2nc(-c3ccc4c(c3)CCN(C(=O)CN)CC4)no2)cc1C#N,,ClCCl,,O=C(O)C(F)(F)F,,test
US04007203,C1CCNC1.O=C1CCS(=O)(=O)c2ccccc21>>O=S1(=O)CC=C(N2CCCC2)c2ccccc21,,O,,c1ccccc1,,test
US20050215556A1,C=CCBr.Nc1cc(Cl)c([N+](=O)[O-])cc1O>>C=CCOc1cc([N+](=O)[O-])c(Cl)cc1N,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150111870A1,COc1nc2ccc(C(O)(c3cnc(C)n3C)c3cnc(C)n3C)cc2c(Cl)c1CO[Si](C)(C)C(C)(C)C.O=S(Cl)Cl>>COc1nc2ccc(C(O)(c3cnc(C)n3C)c3cnc(C)n3C)cc2c(Cl)c1CCl,,C1CCOC1,,,,test
US05258544,C1OCOCO1.Cc1cc(C2=CC(C)(C)CC(C)(C)C2)ccc1F>>Cc1cc(C2=C(C=O)C(C)(C)CC(C)(C)C2)ccc1F,,CC(=O)O,,O=S(=O)(O)O,,test
US20040097507A1,C[Si](C)(C)I.Cc1onc2c1c(=O)n(C1CCCC(CNC(=O)OCc3ccccc3)C1)c1ncccc21>>Cc1onc2c1c(=O)n(C1CCCC(CN)C1)c1ncccc21.I,,ClCCl,,,,test
US20080255086A1,CC(=O)C(C)(C)C.NNC(N)=O>>CC(=NNC(N)=O)C(C)(C)C,,O,,Cl,CC(=O)[O-].[Na+],test
US20040048916A1,CC(C)CN1C(=O)c2cc(Cl)ccc2C1O.CC(C)CN1C(=O)c2ccc(Cl)cc2C1O.CCOC(C)=O.COCCOC>>CCOC(=O)CC1c2cc(Cl)ccc2C(=O)N1CC(C)C.CCOC(=O)CC1c2ccc(Cl)cc2C(=O)N1CC(C)C,,CCOC(C)=O,,O,[H-].[Na+],test
US20150307451A1,Cc1c(Cc2ccc(C#N)cc2F)cc2c(c1C)CN([C@@H]1COCC[C@H]1O)C2=O.OO>>Cc1c(Cc2ccc(C(N)=O)cc2F)cc2c(c1C)CN([C@@H]1COCC[C@H]1O)C2=O,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20080114044A1,COC(=O)CBr.Cc1cc(C=O)ccc1O>>COC(=O)COc1ccc(C=O)cc1C,,CC#N,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20100029657A1,CCN1C2CCC1CC(c1ccnc3c(-c4ccc(N)cc4)c(-c4ccncc4)nn13)C2.CO.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCN1C2CCC1CC(c1ccnc3c(-c4ccc(NC(=O)OC)cc4)c(-c4ccncc4)nn13)C2,,ClCCl,,CCN(CC)CC,,test
US20130331378A1,CNc1ccc2c(Cc3cccc(C(=O)OC)n3)c(-c3ccccc3)nn2c1>>CNc1ccc2c(Cc3cccc(C(=O)O)n3)c(-c3ccccc3)nn2c1,,CO,,Cl,[K+].[OH-],test
US20060252810A1,CCOC(=O)CCSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC(C)=O)c2)n1C>>Cn1c(SCCC(=O)O)nc(-c2ccc(F)cc2)c1-c1ccnc(N)c1,,Cl,,[Na+].[OH-],,test
US20100144745A1,C=C(C)c1cn(COCC[Si](C)(C)C)c2ncc(NC(=O)NC3CCCCC3)nc12>>CC(C)c1cn(COCC[Si](C)(C)C)c2ncc(NC(=O)NC3CCCCC3)nc12,[Pd],CO,,,,test
US20050080074A1,CON(C)C(=O)[C@H]1Cc2ccccc2CN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1Cc2ccccc2C[C@@H]1C=O,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090181942A1,CCOC(=O)/C(Cl)=C/C(=O)[O-].COc1ccc(CNc2ccc(C)cc2C(O)c2cccc(OC)c2Cl)c(OC)c1>>CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2Cl)c2cc(C)ccc2N(Cc2ccc(OC)cc2OC)C1=O,,CCCCCC,,CCOC(C)=O,O=C([O-])O.[Na+],test
US05426187,CCOC(CBr)OCC.Nc1cc(O)nc(N)n1>>Nc1nc(O)c2cc[nH]c2n1,,O,,Cl,CC(=O)[O-].[Na+],test
US20080227797A1,CC(C)(C)OC(=O)N1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3ccc(F)c(F)c3)c2=O)C1.Cl>>Cl.O=c1c2cc(F)cnc2n(-c2ccc(F)c(F)c2)c(=O)n1[C@H]1CCNC1,,C1COCCO1,,,,test
US20090156599A1,CCOc1nc(SC)nc2sc(Cc3c(Cl)cccc3Cl)nc12>>CSc1nc(O)c2nc(Cc3c(Cl)cccc3Cl)sc2n1,,O,,C1COCCO1,Cl,test
US20140315886A1,CN.COc1cc(Br)cc2c(Cl)nc(-c3cccnc3)nc12>>CNc1nc(-c2cccnc2)nc2c(OC)cc(Br)cc12,,C1CCOC1,,,,test
US20050059831A1,CC(=O)OC(C)=O.O=C/C(Cl)=C(/Cl)C(=O)O>>CC(=O)OC1OC(=O)C(Cl)=C1Cl,,ClCCl,,,,test
US20020094989A1,CCOc1ccc(S(=O)(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)cc1.Cl>>CCOc1ccc(S(=O)(=O)CCC2CCNCC2)cc1.Cl,,CCO,,,,test
US20080312307A1,CCOC(=O)c1c(Nc2ccc(I)cc2F)[nH]c2c1CCC2=O.COS(=O)(=O)OC>>CCOC(=O)c1c2c(n(C)c1Nc1ccc(I)cc1F)C(=O)CC2,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120184745A1,CC(C)(C)OC(=O)NCc1ccc(F)c(B(O)O)c1.Clc1ccncc1>>CC(C)(C)OC(=O)NCc1ccc(F)c(-c2ccncc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20090253687A1,CCC(=O)CBr.NC1=NC=C(c2ccc3c(c2)NC(=O)CO3)C(c2ccccc2)S1>>CCc1cn2c(n1)SC(c1ccccc1)C(c1ccc3c(c1)NC(=O)CO3)=C2,,CCO,COCCOC,CCOC(C)=O,O=C([O-])O.[Na+],test
US20160229871A1,CC(C)(C)OC(=O)NCCCOc1ccc(=O)[nH]n1.COC(=O)c1cccc(CBr)c1>>COC(=O)c1cccc(Cn2nc(OCCCNC(=O)OC(C)(C)C)ccc2=O)c1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100160258A1,CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3cc(C(CCC(=O)O)[N+](=O)[O-])ccc3c2C(F)(F)F)CC1>>CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3cc(C(N)CCC(=O)O)ccc3c2C(F)(F)F)CC1,[Zn],,,CC(=O)O,,test
US04895860,COC(=O)CBr.COC(=O)c1cccc(Cl)c1O>>COC(=O)C=Cc1cccc(Cl)c1OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160002255A1,CC1(C)OC(=O)CC(=O)O1.O=C(Cl)C1CCC1>>COC(=O)CC(=O)C1CCC1,,ClC(Cl)Cl,,Cl,c1ccncc1,test
US20120040020A1,CN(C)S(=O)(=O)Cl.Cc1ccc2nc(-c3nc(C4=CCNCC4)cnc3N)[nH]c2c1>>Cc1ccc2nc(-c3nc(C4=CCN(S(=O)(=O)N(C)C)CC4)cnc3N)[nH]c2c1,,CS(C)=O,,CCN(CC)CC,,test
US20130310555A1,CC(C)(C)OC(=O)CN(CCN(CC(=O)OC(C)(C)C)CC(Cc1ccc([N+](=O)[O-])cc1)N(CC(=O)OC(C)(C)C)CC(=O)OC(C)(C)C)CC(=O)OC(C)(C)C>>O=C(O)CN(CCN(CC(=O)O)CC(Cc1ccc([N+](=O)[O-])cc1)N(CC(=O)O)CC(=O)O)CC(=O)O,,C1COCCO1,,CCOCC,Cl,test
US04066651,O=c1cc(CCOCc2ccccc2)c2cc(F)ccc2n1Cc1cc(Br)c(Br)c(Br)c1>>O=c1cc(CCO)c2cc(F)ccc2n1Cc1cc(Br)c(Br)c(Br)c1,[Pd],C1COCCO1,,CCO,Cl,test
US20100152155A1,C1CCOC1.CCN(CC)CC.CCN=C=NCCCN(C)C.O=C(O)c1cnc(N2CC3C(C2)C3NS(=O)(=O)c2ccc3ccccc3c2)nc1.On1nnc2ccccc21>>CC(C)COC(C)ONC(=O)c1cnc(N2CC3C(C2)C3NS(=O)(=O)c2ccc3ccccc3c2)nc1,,ClCCl,,Cl,,test
US04226780,CC(=O)OCC(C)OC(C)=O.CO.COC(C)=O>>CC(O)CO.CO.COC(C)=O,,CO,,,,test
US20040259874A1,CCCN1CCOC(c2ccc(OCc3ccccc3)c(C(=O)OC)c2)C1>>CCCN1CCOC(c2ccc(OCc3ccccc3)c(C(=O)O)c2)C1,,CO,,Cl,[Na+].[OH-],test
US05026856,CCOC(=O)Cl.OCc1cccc2c1CN(Cc1ccccc1)C2>>CCOC(=O)N1Cc2cccc(CO)c2C1,,ClC(Cl)Cl,,O=C([O-])[O-].[Na+].[Na+],,test
US05234935,CCOC(=O)CC(C)=O.COC(=O)C(=Cc1ccc(C(F)(F)F)cc1)C(C)=O.NC1CC1>>CCOC(=O)C1=C(C)N(C2CC2)C(C)=C(C(=O)OC)C1c1ccc(C(F)(F)F)cc1,,c1ccncc1,,Cl,,test
US20100087466A1,CC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)O.CC(C)(C)OC(=O)NCCCCN>>CC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)NCCCCNC(=O)OC(C)(C)C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US04376771,Nc1ccc(C(=O)CCC(=O)O)cc1.O=C(Cl)CCl>>O=C(O)CCC(=O)c1ccc(NC(=O)CCl)cc1,,Cc1ccccc1,,,,test
US05494928,C[C@H](Cn1ccc2cc(F)ccc21)N=[N+]=[N-].O=C(O)/C=C/C(=O)O>>C[C@@H](N)Cn1ccc2cc(F)ccc21.O=C(O)/C=C/C(=O)O,O=[Pt],CCO,,,,test
US20080021028A1,CC(C)OC(=O)C[C@@H](O)C(=O)OC(C)C.CI>>CC(C)OC(=O)[C@@H](O)[C@@H](C)C(=O)OC(C)C,,C1CCOC1,O,[Cl-].[NH4+],C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20090030041A1,CCC(=O)N(c1cccc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)c1)C1(C(=O)OC)CCN(C(=O)OC(C)(C)C)CC1>>CCC(=O)N(c1cccc(N)c1)C1(C(=O)OC)CCNCC1,,O=C(O)C(F)(F)F,,,,test
US20030036655A1,O=[N+]([O-])c1ccc(Cc2ccc(CS(=O)(=O)NCc3ccccc3)cc2)cc1>>Nc1ccc(Cc2ccc(CS(=O)(=O)NCc3ccccc3)cc2)cc1,[Pd],CCOC(C)=O,,,,test
US05075319,CCOC(=O)c1cn(C2CC2)c2c(F)c(-c3cc(C)nc(C)c3)c(F)cc2c1=O>>Cc1cc(-c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)cc(C)n1,,Cl,,CC(=O)[O-].[Na+],,test
US20150353497A1,BrBr.Clc1ccc2nc(Cl)ccc2c1>>Clc1ccc2c(Br)c(Cl)ccc2n1,,CO,O,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20090253669A1,COc1cc(C)c(S(=O)(=O)N2CCCC[C@H]2COCC(=O)OC(C)(C)C)c(C)c1>>COc1cc(C)c(S(=O)(=O)N2CCCC[C@H]2COCC(=O)O)c(C)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050032829A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1nc(Cl)c([N+](=O)[O-])c(NCC(C)(C)N)c1C>>Cc1nc(Cl)c([N+](=O)[O-])c(NCC(C)(C)NC(=O)OC(C)(C)C)c1C,,C1CCOC1,CCCCCC,[Na+].[OH-],,test
US06258833B1,CCOC(=O)/C(C)=C/c1ccc(OC)c(OC2CCCC2)c1.COCN(Cc1ccccc1)C[Si](C)(C)C>>CCOC(=O)C1(C)CN(Cc2ccccc2)CC1c1ccc(OC)c(OC2CCCC2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140364412A1,CC(C)[Si](OCc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCCC[C@@H]5C)n4c3)c3ccccc32)cc1OCCOS(C)(=O)=O)(C(C)C)C(C)C.CNC>>CC(C)[Si](OCc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCCC[C@@H]5C)n4c3)c3ccccc32)cc1OCCN(C)C)(C(C)C)C(C)C,,C1CCOC1,,,,test
US20050222159A1,CC(C)n1nc(-c2nc(S(C)(=O)=O)c(N)nc2-c2ccccc2)ccc1=O.CCCCO>>CCCCOc1nc(-c2ccc(=O)n(C(C)C)n2)c(-c2ccccc2)nc1N,,CCCCCC,,Cl,[H-].[Na+],test
US05616579,CCOC(=O)c1nocc1O.NC/C=C\COc1cc(CN2CCCCC2)ccn1>>O=C(NC/C=C\COc1cc(CN2CCCCC2)ccn1)c1nocc1O,,Cc1ccccc1,,,,test
US20080242663A1,COS(=O)(=O)OC.Oc1c(Br)cc(F)cc1Br>>COc1c(Br)cc(F)cc1Br,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110053972A1,Cn1nccc1-c1cc(C(=O)O)c(Cl)n1C.N[C@@H](Cc1ccccc1C(F)(F)F)CN1C(=O)c2ccccc2C1=O>>Cn1nccc1-c1cc(C(=O)N[C@@H](Cc2ccccc2C(F)(F)F)CN2C(=O)c3ccccc3C2=O)c(Cl)n1C,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20050277645A1,CC(C)(C)[Si](C)(C)OCCC1Cc2cc(F)ccc2C1=O.Cc1cccnn1>>OCCC1=C(Cc2cccnn2)c2ccc(F)cc2C1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US05612373,CN(NC(=O)c1ccc(C#N)cc1)C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CNNC(=O)c1ccc(C#N)cc1.O=C(O)C(F)(F)F,,ClCCl,,COc1ccccc1,,test
US20100197716A1,CC(C)(C)CN1CCC2(CC1)CN(c1ccccc1NC(=S)NC(=O)c1ccccc1)c1ccccc12>>CC(C)(C)CN1CCC2(CC1)CN(c1ccccc1NC(N)=S)c1ccccc12,,C1CCOC1,CO,[Li+].[OH-],,test
US20090291938A1,CC(C)(C)[Si](C)(C)Cl.CC1(O)CN(C2CCCC2)c2nc(Cl)ncc2NC1=O>>CC1(O[Si](C)(C)C(C)(C)C)CN(C2CCCC2)c2nc(Cl)ncc2NC1=O,,C1CCOC1,CN(C)C=O,c1c[nH]cn1,,test
US20060235029A1,CCCN.CCN(CC)CCCNc1nc(-c2cc(C(=O)O)cc(F)c2C)c2ccc(=O)n(-c3c(F)cccc3F)c2n1>>CCCNC(=O)c1cc(F)c(C)c(-c2nc(NCCCN(CC)CC)nc3c2ccc(=O)n3-c2c(F)cccc2F)c1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090181950A1,COC(=O)CCc1ccc2cccc(N3CCN(C(=O)OC(C)(C)C)CC3)c2n1>>COC(=O)CCc1ccc2cccc(N3CCNCC3)c2n1,,CO,ClCCl,O=C(O)C(F)(F)F,,test
US20160264567A1,CC(C)(C)[Si](C)(C)Cl.OCc1cc(Br)ncc1F>>CC(C)(C)[Si](C)(C)OCc1cc(Br)ncc1F,,O,,CN(C)C=O,c1c[nH]cn1,test
US20060194986A1,CC(C)OC(=O)N=NC(=O)OC(C)C.CCOC(=O)C(C#N)c1ccccc1>>CCOC(=O)[C@@](C#N)(c1ccccc1)N(NC(=O)OC(C)C)C(=O)OC(C)C,,Cc1ccccc1,,,,test
US20070149519A1,COc1cc2ncn(-c3cc(OCC4CCCCC4)c(C(N)=O)s3)c2cc1OC>>COc1cc2ncn(-c3cc(OCC4CCCCC4)c(C#N)s3)c2cc1OC,,CO,CS(C)=O,,,test
US20130217699A1,C1CCOC1.CC(=O)c1sc(C(=O)[O-])c2c1CCCC2.O=C(c1cc(Cl)cc(Cl)c1)C(F)(F)F>>COC(=O)c1sc(C(=O)CC(O)(c2cc(Cl)cc(Cl)c2)C(F)(F)F)c2c1CCCC2,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20030134993A1,Cc1ccc(C)c2c1C=CC2.[Li]CCCC>>[Li]C1C=Cc2c(C)ccc(C)c21,,C1CCOC1,,,,test
US20030220364A1,Cc1cccc(C)c1CNc1cccn2c(C)c(C)nc12.O=[N+]([O-])O>>Cc1cccc(C)c1CNc1c([N+](=O)[O-])ccn2c(C)c(C)nc12,,CC(=O)O,,,,test
US20100311966A1,C=O.CC(C)(C)OC(=O)N1CC[C@H](NC(=O)OCc2ccccc2)[C@H](N)C1.CO>>CN(C)[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1NC(=O)OCc1ccccc1,,C1CCOC1,CO,CC(=O)O,[BH3-]C#N.[Na+],test
US20090247534A1,Fc1ccc(Br)cn1.Nc1ccc(C(F)(F)F)nc1>>FC(F)(F)c1ccc(Nc2ccc(Br)cn2)cn1,,CCCCO,,Cl,,test
US20090286984A1,COCCN(Cc1ccc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)nc1)C(=O)OC(C)(C)C.O=C(Cc1ccc(F)cc1)N=C=S>>COCCN(Cc1ccc(-c2cc3nccc(Oc4ccc(NC(=S)NC(=O)Cc5ccc(F)cc5)cc4F)c3s2)nc1)C(=O)OC(C)(C)C,,Cc1ccccc1,,CCO,,test
US20090306139A1,CC(C)(C)OC(=O)N1CC(c2ccc(C(F)(F)F)cc2)CC(c2nc(-c3cccc(F)c3)no2)C1>>Fc1cccc(-c2noc(C3CNCC(c4ccc(C(F)(F)F)cc4)C3)n2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04616086,CCOC(=O)c1ccc(N2CCNCC2)cc1.O=C(CBr)c1ccc(Cl)cc1>>CCOC(=O)c1ccc(N2CCN(CC(=O)c3ccc(Cl)cc3)CC2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US03984573,CCO.O=C(O)c1ccccc1S>>CCOC(=O)c1ccccc1S,,c1ccccc1,,O=S(=O)(O)O,,test
US20020006635A1,Nc1nc(NC2CC2)c2ncn(C3CO[C@@H](COC(=O)c4ccccc4)O3)c2n1>>Nc1nc(NC2CC2)c2ncn(C3CO[C@@H](CO)O3)c2n1,,CO,,N,,test
US20160002188A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(Br)cc2F)CC1.OB(O)c1ccc(Cl)cc1F>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(-c3ccc(Cl)cc3F)cc2F)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20110059034A1,CCCCCCCCCCCCCCCCBr.CCCCCCCCOC1=C(O)C(=O)O[C@]1(CC(O)CO)[C@@H](O)CO>>CCCCCCCCCCCCCCCCOC1=C(OCCCCCCCC)[C@@](CC(O)CO)([C@@H](O)CO)OC1=O,,CS(C)=O,,O=C([O-])O.[Na+],,test
US20100152168A1,Br.NC(Cc1ccccc1)C(=O)O>>O=C(O)C(Br)Cc1ccccc1,,O,,O=N[O-].[Na+],,test
US05510326,CC1=C(C2COC(C)(C)C2)CCC1(C)C>>CC1C(C2COC(C)(C)C2)CCC1(C)C,[Pd],CCO,,,,test
US20140128383A1,CCOC(=O)C(=O)c1sc(Br)cc1Br>>CCOC(=O)C(O)c1sc(Br)cc1Br,Cl,C1CCOC1,,[BH4-].[Na+],,test
US20080090822A1,CC(=O)c1c(Cl)cc(N2CCN(C(=O)OC(C)(C)C)CC2)cc1Cl>>CC(=O)c1c(Cl)cc(N2CCNCC2)cc1Cl,,O,,O=C(O)C(F)(F)F,,test
US20040006067A1,CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(c2ccccc2NS(=O)(=O)c2ccccc2C#N)CC1>>N#Cc1ccccc1S(=O)(=O)Nc1ccccc1C1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@@H]2Cc3ccccc3CN2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100087427A1,CC(C)c1cccc([C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN(Cc2ccccc2)c2ccc(Cl)cc2)c1>>CC(C)c1cccc([C@@H]2CNC[C@@H]2CN(Cc2ccccc2)c2ccc(Cl)cc2)c1,,C1COCCO1,Cl,,,test
US20070043080A1,CC(C)C(=O)Nc1cccc(C2CCN(CCN)CC2)c1.O=C(Cl)c1ccc2ccccc2c1>>CC(C)C(=O)Nc1cccc(C2CCN(CCNC(=O)c3ccc4ccccc4c3)CC2)c1,,C1CCOC1,,,,test
US20110142796A1,COc1ccc2c3cnc(N)nc3n(C3CCCC3)c2n1>>Nc1ncc2c3ccc(O)nc3n(C3CCCC3)c2n1,,Cl,,O=C([O-])O.[Na+],,test
US20090137609A1,CCC(CC)(c1ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1ccc(-c2ccc(CC(=O)OC)c(Cl)c2)c(C)c1>>CCC(CC)(c1ccc(CCC(O)C(C)(C)C)c(C)c1)c1ccc(-c2ccc(CC(=O)OC)c(Cl)c2)c(C)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060189606A1,CCn1c(-c2cccc(NC(=S)NC(=O)c3ccccc3)c2)c(C#N)c2ccc(OC)cc21>>CCn1c(-c2cccc(NC(N)=S)c2)c(C#N)c2ccc(OC)cc21,,CO,O,[Na+].[OH-],,test
US20150133400A1,CC1(C)OBOC1(C)C.Cc1noc(C)c1-c1cnc2c(I)cn(CC3CCC(F)(F)CC3)c2c1>>Cc1noc(C)c1-c1cnc2c(B(O)O)cn(CC3CCC(F)(F)CC3)c2c1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20050080124A1,CN(C)CCO.Cn1ncc(Cl)c1-c1cc(NC(=O)Nc2ccc(F)cc2F)ccc1O>>CN(C)CCOc1ccc(NC(=O)Nc2ccc(F)cc2F)cc1-c1c(Cl)cnn1C,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05763450,CCOC(=O)C(=CN(C)C)C(=O)c1ccc(Br)cc1Cl.NC1CCCCC1>>CCOC(=O)c1cn(C2CCCCC2)c2cc(Br)ccc2c1=O,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US05270309,Br.CC(C)N(CCOC(=O)c1cc(OCc2ccccc2)c2c(Cl)cc(Cl)cc2n1)C(C)C>>Br.CC(C)N(CCOC(=O)c1cc(=O)c2c(Cl)cc(Cl)cc2[nH]1)C(C)C,,CC(=O)O,,,,test
US04640703,CC(Br)C(=O)Br.CCCCNC#N>>CCCCN(C#N)C(=O)C(C)Br,,CCOCC,,CCN(CC)CC,,test
US20120053173A1,CC(=O)c1nc(Br)ccc1O.O=C(CBr)C1CCCCC1>>Cc1c(C(=O)C2CCCCC2)oc2ccc(Br)nc12,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20060167053A1,COCOc1cc(O)cc(C(=O)OC)c1.Fc1cc(I)ccc1Br>>COCOc1cc(Oc2ccc(Br)c(F)c2)cc(C(=O)OC)c1,O=[Cu],c1ccncc1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040147608A1,CC(C)(C)OC(=O)NCC1(C(=O)O)CC12CCCCC2.Cl>>Cl.NCC1(C(=O)O)CC12CCCCC2,,C1COCCO1,,CCOCC,,test
US20100048561A1,Clc1ncc2ccc(Br)cc2n1.Nc1ccc(S(=O)(=O)NCCCN2CCCC2)cc1>>O=S(=O)(NCCCN1CCCC1)c1ccc(Nc2ncc3ccc(Br)cc3n2)cc1,,CC(C)O,CCOC(C)=O,C1COCCO1,Cl,test
US20130072487A1,CCCCCCN=C=O.NCc1ccccc1>>CCCCCCN(Cc1ccccc1)C(N)=O,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,Cl,test
US20060234997A1,COc1ccc2c(c1)C(=O)C(C)(C)CC2.NO>>COc1ccc2c(c1)NC(=O)C(C)(C)CC2,,c1ccncc1,,Cl,,test
US20100233116A1,CS(=O)(=O)Cl.Cc1nc(-n2cnn(CCO)c2=O)sc1C(=O)NCc1cccnc1>>Cc1nc(-n2cnn(CCOS(C)(=O)=O)c2=O)sc1C(=O)NCc1cccnc1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20060058325A1,COc1cc2c(Nc3cnc(NC(=O)c4ccc(F)c(Cl)c4)nc3)ncnc2cc1OCc1ccccc1>>COc1cc2c(Nc3cnc(NC(=O)c4ccc(F)c(Cl)c4)nc3)ncnc2cc1O,,O=C(O)C(F)(F)F,,,,test
US04279992,CCOC(=O)C(C(=O)OCC)c1ccccc1.N#CCCCBr>>CCOC(=O)C(CCCC#N)(C(=O)OCC)c1ccccc1,,CN(C)C=O,,[H][H],[H-].[Na+],test
US20100292279A1,CC(C)(C)N.COc1ccc(Br)c(S(=O)(=O)Cl)c1>>COc1ccc(Br)c(S(=O)(=O)NC(C)(C)C)c1,,ClCCl,,CCN(CC)CC,,test
US04066773,COCCNCC(=O)OC(C)(C)C.Cc1ccccc1S(=O)(=O)O.OCc1ccccc1>>COCCNCC(=O)OCc1ccccc1.Cc1ccc(S(=O)(=O)O)cc1,,c1ccccc1,,O,O,test
US05858995,Cc1oc2c(NC(=O)c3c(Cl)cccc3Cl)cc(NC(=O)OC(C)(C)C)cc2c1C.Cl>>Cc1oc2c(NC(=O)c3c(Cl)cccc3Cl)cc(N)cc2c1C.Cl,,CCOC(C)=O,,CCOCC,,test
US20120142717A1,COC(=O)/C=C/c1cncnc1>>COC(=O)CCc1cncnc1,[Pd],CO,,,,test
US05210193,FC(F)(F)C1CNCCN1.O=C(O)c1cn(C2CC2)c2cc(F)c(F)cc2c1=O>>O=C(O)c1cn(C2CC2)c2cc(N3CCNC(C(F)(F)F)C3)c(F)cc2c1=O,,c1ccncc1,,,,test
US20060264490A1,CCS(=O)(=O)Nc1ccc(NCC2CCC(F)(F)CC2)c([N+](=O)[O-])c1>>CCS(=O)(=O)Nc1ccc(NCC2CCC(F)(F)CC2)c(N)c1,[Pd],CCOC(C)=O,CO,,,test
US04410539,COC(=O)c1sc2cc(OC)ccc2c1C>>COC(=O)c1sc2cc(O)ccc2c1C,,ClCCl,,BrB(Br)Br,CO,test
US20060183756A1,CC(=O)Nc1nc(C)c(S(=O)(=O)Cl)s1.NCCO>>CC(=O)Nc1nc(C)c(S(=O)(=O)NCCO)s1,,C1COCCO1,,CCN(CC)CC,,test
US20090012077A1,ClCCN1CCCC1.N#CC1(NC(=O)[C@@H]2CCCC[C@H]2C(=O)N2CCc3[nH]c4c(O)cccc4c3C2)CC1>>N#CC1(NC(=O)[C@@H]2CCCC[C@H]2C(=O)N2CCc3[nH]c4c(OCCN5CCCC5)cccc4c3C2)CC1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20040023806A1,CO/N=C(C)/C=N/OC(C)c1ccccc1NC(=O)OC.COCCl>>COCN(C(=O)OC)c1ccccc1C(C)O/N=C/C(C)=N/OC,,CN(C)C=O,,[H][H],[H-].[Na+],test
US04312869,Brc1nc(Cc2ccc(Sc3ccccc3)cc2)cs1.O=C(OO)c1cccc(Cl)c1>>O=S(c1ccccc1)c1ccc(Cc2csc(Br)n2)cc1,,ClC(Cl)Cl,,,,test
US20020047103A1,CCCC[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](CCl)CC2)CC1.CO[Si](OC)(OC)OC>>CCCC[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](C[Si](OC)(OC)OC)CC2)CC1,,C1CCOC1,,[Mg],,test
US20100261755A1,CCOC(=O)C1CCN(C(=O)OCc2ccccc2)C(C#N)C1.[N-]=[N+]=[N-]>>CCOC(=O)C1CCN(C(=O)OCc2ccccc2)C(c2nnn[nH]2)C1,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US20100209462A1,CCCCCC(CCC)C(=O)O.CCCCCCCCO>>CCCCCCCCOC(=O)C(CCC)CCCCC,,O,,,,test
US20030220341A1,O=C1c2ccccc2C(=O)N1CCCCN(Cc1nc2c([nH]1)CCCC2)C1CCCc2cccnc21>>NCCCCN(Cc1nc2c([nH]1)CCCC2)C1CCCc2cccnc21,,CCO,,NN,O,test
US20120071460A1,COCC(=O)CC(=O)OC.NC(=NO)c1cc(F)ccc1F>>COCC(=O)Cc1nc(-c2cc(F)ccc2F)no1,,CC#N,Cc1ccccc1,ClCCl,O,test
US04192888,Br.C=CC(=O)OC.Nc1ccccc1Cl>>COC(=O)C(Br)Cc1ccccc1Cl,,CC(C)=O,O,O=N[O-].[Na+],,test
US20110178091A1,CC(C)(C)OC(=O)N1CCN(c2cccc3cccnc23)CC1.O=S(Cl)Cl>>Cl.c1cnc2c(N3CCNCC3)cccc2c1,,CO,,,,test
US20100168063A1,COC(=O)c1nc2ccc(C)cn2c(=O)c1OCc1ccccc1.NN>>Cc1ccc2nc(C(=O)NN)c(OCc3ccccc3)c(=O)n2c1,,CO,,,,test
US06723727B1,CC(C)(C)OC(=O)NCCCCNc1nc2ccccc2[nH]1>>NCCCCNc1nc2ccccc2[nH]1,,O=C(O)C(F)(F)F,,,,test
US20130102776A1,CC(C)(C)OC(=O)N1CCN(Cc2c(O)ccc3c2OCC3=O)CC1.O=Cc1cn(S(=O)(=O)c2ccc(C(F)(F)F)cc2)c2ccccc12>>CC(C)(C)OC(=O)N1CCN(Cc2c(O)ccc3c2O/C(=C\c2cn(S(=O)(=O)c4ccc(C(F)(F)F)cc4)c4ccccc24)C3=O)CC1,,CO,,C1CCNCC1,,test
US20040147612A1,CC(C)S(=O)(=O)Cl.CC(C)S(=O)(=O)N[C@@H]1CCC[C@@H]1c1ccc(N(CCN)Cc2ccccc2)cc1>>CC(C)S(=O)(=O)N[C@H]1CCC[C@H]1c1ccc(NCCNS(C)(=O)=O)cc1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20060264631A1,CC(C)(C)c1ccc(C(=O)O)cc1.Nc1cccc([N+](=O)[O-])c1O>>CC(C)(C)c1ccc(C(=O)Nc2cccc([N+](=O)[O-])c2O)cc1,,ClCCl,,O,O=C(n1ccnc1)n1ccnc1,test
US20050009829A1,O=c1ccn(-c2ccc([N+](=O)[O-])cc2)cc1>>Nc1ccc(-n2ccc(=O)cc2)cc1,,CCO,CCOC(C)=O,,,test
US20140155389A1,COC(=O)c1c(/C=N/NC(=O)OC(C)(C)C)cc(Cl)nc1Cl>>O=c1[nH]ncc2cc(Cl)nc(Cl)c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040097563A1,CCNc1ccc(-c2cc(-c3c(OCc4ccc(OC)cc4)cccc3OCC3CC3)nc(N)c2CO)cc1O>>CCNc1ccc(-c2cc(-c3c(O)cccc3OCC3CC3)nc(N)c2CO)cc1O,,C1COCCO1,CCOCC,Cl,,test
US20080001120A1,O=C(Oc1ccc([N+](=O)[O-])cc1)c1ccc([N+](=O)[O-])cc1>>Nc1ccc(OC(=O)c2ccc(N)cc2)cc1,[Pd],CCOC(C)=O,,[H][H],,test
US20090124625A1,BrCCCCC#Cc1ccccn1.c1ccc2[nH]ncc2c1>>C(#Cc1ccccn1)CCCCn1cc2ccccc2n1,,C1CCCCC1,CCOC(C)=O,,,test
US20140148400A1,CC(O)Cl.O=c1ccc2ccc(O)cc2o1>>O=c1ccc2ccc(OCCO)cc2o1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100081653A1,CC(C)(C)OC(=O)C(C#N)=C1N=C(C(F)(F)F)C=CN1>>N#CCc1nccc(C(F)(F)F)n1,,Cl,,C1COCCO1,,test
US20110144131A1,CCOC(=O)CN1CCC(c2nc3cc(-c4ccc(Cl)cc4Cl)nc(NCCNc4ccc(C#N)cn4)n3n2)CC1>>N#Cc1ccc(NCCNc2nc(-c3ccc(Cl)cc3Cl)cc3nc(C4CCN(CC(=O)O)CC4)nn23)nc1,,COCCOC,,O,[Na+].[OH-],test
US20110237620A1,Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)sc3n2)ccc1Cl.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)sc3n2)ccc1Cl,,CCOC(C)=O,CN(C)C=O,,,test
US20120270838A1,CC(C)(C)OC(=O)N1CCC(N)(C(N)=O)CC1.O=C(O)c1ccc(C(F)(F)F)cc1F>>CC(C)(C)OC(=O)N1CCC(NC(=O)c2ccc(C(F)(F)F)cc2F)(C(N)=O)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120157430A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1c(C(C)N)cc(Cl)c(C)c1Br>>COc1c(C(C)NC(=O)OC(C)(C)C)cc(Cl)c(C)c1Br,,C1CCOC1,,CCN(CC)CC,,test
US20040058903A1,CC(=O)Nc1cccc(CCc2ccc(N)cc2)n1.COc1ccc(-c2ccccc2C(=O)Cl)cc1>>COc1ccc(-c2ccccc2C(=O)Nc2ccc(CCc3cccc(NC(C)=O)n3)cc2)cc1,,C1CCOC1,O,CCN(CC)CC,CCOC(C)=O,test
US20100249189A1,O=C(Oc1ccc([N+](=O)[O-])cc1)O[C@@H]1CO[C@@H]2[C@H](O)CO[C@H]12.OCCCCCCCl>>O=C(OCCCCCCCl)O[C@@H]1CO[C@@H]2[C@H](O)CO[C@H]12,CN(C)c1ccncc1,ClCCl,,,,test
US04803280,CCOC(=O)CCSC(CC(C)(C)C)=NNC(=O)OC.O=S(Cl)Cl>>CCOC(=O)CCSc1nnsc1C(C)(C)C,,ClCCl,,,,test
US20120142714A1,CCOC(C)=O.C[C@@H](COc1cnc(-c2nc3ccc(OCC4CC(F)(F)C4)cc3o2)c(F)c1)NC(=O)OC(C)(C)C>>CC(=O)N[C@@H](C)COc1cnc(-c2nc3ccc(OCC4CC(F)(F)C4)cc3o2)c(F)c1,,CCOC(C)=O,,Cl,,test
US20060004017A1,CNC.COc1cc2c(Oc3ccc4[nH]cc(C)c4c3)ncnc2cc1OC[C@H]1CO1>>COc1cc2c(Oc3ccc4[nH]cc(C)c4c3)ncnc2cc1OC[C@H](O)CN(C)C,,CN(C)C=O,,CCO,,test
US06511974B1,O=C(Cl)c1ccccc1-c1ccccc1.O=C(c1ccc(-c2cc[nH]n2)cc1)N1Cc2cccn2Cc2ccccc21>>O=C(c1ccc(-c2ccn(C(=O)c3ccccc3-c3ccccc3)n2)cc1)N1Cc2cccn2Cc2ccccc21,,c1ccncc1,,,,test
US20130079338A1,FC(F)Oc1ccc(Nc2ccc(CCc3ccc4c(cnn4C4CCCCO4)c3)nn2)cc1>>FC(F)Oc1ccc(Nc2ccc(CCc3ccc4[nH]ncc4c3)nn2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04349684,COC(=O)CCCCCCCn1c(-c2ccccc2)c(-c2ccccc2)n(C)c1=O>>Cn1c(-c2ccccc2)c(-c2ccccc2)n(CCCCCCCC(=O)O)c1=O,,CO,,[Na+].[OH-],,test
US20150353553A1,CC(C)c1ccnc(-c2nc3nc(CN)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)c1.CS(=O)(=O)Cl>>CC(C)c1ccnc(-c2nc3nc(CNS(C)(=O)=O)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20140088046A1,CS(=O)(=O)Cc1ccc(Br)cn1.O=S(=O)(c1ccccc1)N(F)S(=O)(=O)c1ccccc1>>CS(=O)(=O)C(F)c1ccc(Br)cn1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20110178060A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCCNc1ccccc1>>CC(C)(C)OC(=O)N(CCO)c1ccccc1,,C1CCOC1,,,,test
US06350907B1,C[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C/C=C/c1ccc(-c2ccccc2)c(Cl)c1)CC(=O)OC(C)(C)C)C(C)(C)C)c1ccccc1>>C[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCc1ccc(-c2ccccc2)c(Cl)c1)CC(=O)OC(C)(C)C)C(C)(C)C)c1ccccc1,,CCOCC,Cc1ccccc1,,,test
US20160222022A1,COC(=O)c1ccc(CNC(CO)c2cccnc2)c(Br)c1>>COC(=O)c1ccc2c(c1)OCC(c1cccnc1)NC2,[Cu]I,CC(C)O,,O=C([O-])[O-].[K+].[K+],,test
US20050130997A1,O=C1CCC(=O)N1Cl.ON=Cc1cccs1>>ON=C(Cl)c1cccs1,,CN(C)C=O,Cl,,,test
US20120115813A1,C=Cc1ccc(OCC)c2c1C(C[N+](=O)[O-])OB2O>>C=Cc1ccc(OCC)c2c1C(CN)OB2O,[Ni],CCO,,N,,test
US20040242596A1,CCC(NCCCNC(=O)OC(C)(C)C)c1nc2snc(C)c2c(=O)n1Cc1ccccc1.O=C(Cl)c1ccc(Cl)cc1>>CCC(c1nc2snc(C)c2c(=O)n1Cc1ccccc1)N(CCCNC(=O)OC(C)(C)C)C(=O)c1ccc(Cl)cc1,,ClCCl,,CCN(CC)CC,,test
US20060287363A1,C=O.CN1CCC(Nc2cccc(NC(=O)OC(C)(C)C)c2)CC1>>CN1CCC(N(C)c2cccc(NC(=O)OC(C)(C)C)c2)CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US04438143,CC(C)N.CCCCCC(=O)Nc1ccc(OCC2CO2)c(C#N)c1>>CCCCCC(=O)Nc1ccc(OCC(O)CNC(C)C)c(C#N)c1,,CCO,,,,test
US20020019558A1,O=C(C=Cc1ccccc1)OC(COc1ccc([N+](=O)[O-])cc1)COc1ccc([N+](=O)[O-])cc1>>Nc1ccc(OCC(COc2ccc(N)cc2)OC(=O)C=Cc2ccccc2)cc1,[Fe],C1COCCO1,,C,,test
US20090181319A1,N#Cc1ccc(S(=O)(=O)Cl)cc1.O=C([O-])[O-].[Ag+2]>>N#Cc1ccc(S(=O)(=O)[O-])cc1.[Ag+],,CC#N,O,CCCCCC,CCOC(C)=O,test
US20050239786A1,CC(C)(C)OC(=O)NCCN.O=Cc1ccc(F)cc1Cl>>CC(C)(C)OC(=O)NCCNCc1ccc(F)cc1Cl,,CO,,[BH4-].[Na+],,test
US20150232463A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc(C)c(-c2ccc(O)cc2)c1N1CCC(C)(C)CC1.Cc1noc(C)c1CCO>>Cc1noc(C)c1CCOc1ccc(-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(=O)O)c2N2CCC(C)(C)CC2)cc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080176839A1,COC(=O)Cc1ccc(Cl)c(Cl)c1.COC(CBr)OC>>COC(=O)C(CC=O)c1ccc(Cl)c(Cl)c1,,CN(C)C=O,,[H-].[Na+],,test
US04633277,BrCCOc1ccccc1.Oc1ccc(O)cc1>>Oc1ccc(OCCOc2ccccc2)cc1,,O,,[K+].[OH-],,test
US20100010053A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c(C(=O)NCC(=O)[O-])c[nH]c34)no2)cc1Cl>>CC(C)Oc1ccc(-c2nc(-c3cccc4c(C(=O)NCC(=O)O)c[nH]c34)no2)cc1Cl,,C1CCOC1,,Cl,[Na+].[OH-],test
US20110224225A1,O=S(Cl)Cl.OCc1cccnc1>>Cl.ClCc1cccnc1,,ClC(Cl)Cl,,,,test
US20110195948A1,CC(C)(C)C(=O)OC(=O)C(C)(C)C.Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12>>CC(C)(C)C(=O)Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12,,ClCCl,,c1ccncc1,,test
US20100137587A1,C1CCOC1.CC(C)CN(C(=O)OCc1ccccc1)[C@H]1C[C@@H](CO)CN(C(=O)OC(C)(C)C)C1.O=C1NC(=O)c2ccccc21>>CC(C)CN[C@H]1C[C@@H](CN2CCCC2=O)CN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050272036A1,CNc1ccc(Cl)cc1.CS(=O)(=O)Cl>>CN(c1ccc(Cl)cc1)S(C)(=O)=O,,c1ccncc1,,,,test
US20080194576A1,O=C(O)c1cc(Cl)nc(-c2ccccc2)n1.OCCO>>O=C(O)c1cc(OCCO)nc(-c2ccccc2)n1,,C1CCOC1,,Cl,[H-].[Na+],test
US20160096839A1,COc1cc(-c2c(-n3cc([Si](C)(C)C)nn3)ccc(Cl)c2F)ncn1.O=C1CCC(=O)N1Cl>>COc1cc(-c2c(-n3cc(Cl)nn3)ccc(Cl)c2F)ncn1,,CC#N,,,,test
US20080015202A1,CC(=O)Nc1nc(-c2ccc(CCC(=O)CN)cc2)cs1.N#CN>>CC(=O)Nc1nc(-c2ccc(CCc3cnc(N)[nH]3)cc2)cs1,,O,,Cl,[Na+].[OH-],test
US20100305145A1,CCOC(=O)CCNS(=O)(=O)c1ccccc1>>O=C(O)CCNS(=O)(=O)c1ccccc1,,CCO,,O,[Na+].[OH-],test
US20090209607A1,CCc1sc(C(=O)O)cc1-c1c(Br)cnn1C.N[C@@H](Cc1ccccc1C(F)(F)F)CN1C(=O)c2ccccc2C1=O>>CCc1sc(C(=O)N[C@@H](Cc2ccccc2C(F)(F)F)CN2C(=O)c3ccccc3C2=O)cc1-c1c(Br)cnn1C,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20040058907A1,CC(C)(C)OC(=O)N1CCOC(CNC(=O)Nc2ccc(Cl)cc2)C1>>O=C(NCC1CNCCO1)Nc1ccc(Cl)cc1,,C1COCCO1,Cl,,,test
US20060142339A1,CI.Cc1ccc(S(=O)(=O)OC[C@@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2O)cc1>>CO[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@H]1COS(=O)(=O)c1ccc(C)cc1,,C1CCOC1,,O,[H-].[Na+],test
US20120114739A1,Clc1cc(C2CCC3(CC2)OCCO3)nc2ccnn12.N>>Nc1cc(C2CCC3(CC2)OCCO3)nc2ccnn12,,CO,ClCCl,,,test
US20040122244A1,C1CCNCC1.COC1=C(OC)C(=O)C(Cc2cccc(C(=O)O)c2OCc2ccccc2)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2cccc(C(=O)N3CCCCC3)c2OCc2ccccc2)=C(C)C1=O,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20050009799A1,C=C(c1ccc(OCc2ccccc2)cc1)[Sn](CCCC)(CCCC)CCCC.CCOC(C)=O.CN(C)C=O>>C=C(C(=C)c1ccc(OCc2ccccc2)cc1)c1ccc(OCc2ccccc2)cc1,Cl[Cu],CCOC(C)=O,CN(C)C=O,,,test
US20030153752A1,N#Cc1ccccc1F.Oc1ccc(Br)cc1>>N#Cc1ccccc1Oc1ccc(Br)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030087901A1,CC(=O)Cl.COc1ccc2c(c1)CCN(c1ccc(N)cc1)C2Cc1ccc(OCc2ccccc2)cc1>>COc1ccc2c(c1)CCN(c1ccc(NC(C)=O)cc1)C2Cc1ccc(OCc2ccccc2)cc1,,ClCCl,,,,test
US20070105819A1,CCCCC1=Nc2cc(C(=O)N(C)OC)ccc2Sc2ccccc21.Cl[Mg]C1CCCCC1>>CCCCC1=Nc2cc(C(=O)C3CCCCC3)ccc2Sc2ccccc21,,C1CCOC1,CCOCC,,,test
US05098701,C=C(C)C(=O)OC(=O)C(=C)C.OCCCc1cccnc1>>C=C(C)C(=O)OCCCc1cccnc1,,COC(C)(C)C,,O,,test
US20090233928A1,O=[N+]([O-])c1cnc(N2CCOCC2)c(Cl)c1>>Nc1cnc(N2CCOCC2)c(Cl)c1,[Pd],CCO,,[H][H],,test
US20140235855A1,COC(=O)C[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CO1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CC(=O)O)OC1,,CO,O,[Li+].[OH-],,test
US04536503,ClCCCCCCCCOc1cccc2ccccc12.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1CCCCCCCCOc1cccc2ccccc12,,CN(C)C=O,,O,[K],test
US04012380,CC(=O)OC(C)=O.CC(O)C1=CS[C@@H]2C(NC(=O)Cc3cccs3)C(=O)N2C1C(=O)OC(c1ccccc1)c1ccccc1>>CC(=O)OC(C)C1=CS[C@@H]2C(NC(=O)Cc3cccs3)C(=O)N2C1C(=O)OC(c1ccccc1)c1ccccc1,,ClCCl,,c1ccncc1,,test
US20060116410A1,CNC(=O)CCl.CS(=O)(=O)Nc1cc(Cl)cc(C(=O)NCc2ccc(C#N)cc2O)c1>>CNC(=O)COc1cc(C#N)ccc1CNC(=O)c1cc(Cl)cc(NS(C)(=O)=O)c1,,CC#N,,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US04038280,CC1(C)CC(c2ccc(O)cc2)CC(C)(C)N1.Cl>>CC1(C)CC(c2ccc(O)cc2)CC(C)(C)N1.Cl,,CO,,,,test
US20100113510A1,CC(C(=O)O[C@H]1CN2CCC1CC2)(c1cccs1)N1CCCCC1.CN(C(=O)CBr)c1cccc(F)c1>>CN(C(=O)C[N+]12CCC(CC1)[C@@H](OC(=O)C(C)(c1cccs1)N1CCCCC1)C2)c1cccc(F)c1.[Br-],,CC#N,,CCOCC,,test
US20160009712A1,CI.O=c1[nH]c2ncc(Br)cc2o1>>Cn1c(=O)oc2cc(Br)cnc21,,CN(C)C=O,,[H-].[Na+],,test
US20130217664A1,CN(c1cc2c(cn1)ncn2C)c1ccc(CNS(C)(=O)=O)cc1F.N#CCBr>>CN(c1cc2c(cn1)ncn2C)c1ccc(CN(CC#N)S(C)(=O)=O)cc1F,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US05262420,CCc1ccncc1.Clc1ccccc1CCBr>>CC(CCc1ccccc1Cl)c1ccncc1,,C1CCOC1,O,CC(C)NC(C)C,[Li]CCCC,test
US05344843,COC(=O)C(=O)c1ccc(N(C=O)CCOc2ccc3ccccc3c2)cc1>>O=CN(CCOc1ccc2ccccc2c1)c1ccc(C(=O)C(=O)O)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20070117845A1,Cl.N#CC(N=C(c1ccccc1)c1ccccc1)c1ncc(C(F)(F)F)cc1Cl>>Cl.N#CC(N)c1ncc(C(F)(F)F)cc1Cl,,Cl,ClCCl,,,test
US05124330,COc1cccc(C(O)c2ccc(Br)cc2)c1.O=S(Cl)Cl>>COc1cccc(C(Cl)c2ccc(Br)cc2)c1,,ClCCl,,,,test
US20100234365A1,N#Cc1ccccc1F.O=C1OC[C@H](c2cccc(O)c2)N1c1ccc(Cl)cc1>>N#Cc1ccccc1Oc1cccc([C@H]2COC(=O)N2c2ccc(Cl)cc2)c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070249659A1,CCOC(=O)c1ccc(O)cc1.ClCc1ccc(Cl)nc1>>CCOC(=O)c1ccc(OCc2ccc(Cl)nc2)cc1,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20050049260A1,COc1ccc(-c2nn3c(NCCCCN)cccc3c2-c2ccnc(NC3CCCC3)n2)cc1.O=C1N[C@H]2CS[C@@H](CCCCC(=O)ON3C(=O)CCC3=O)[C@H]2N1>>COc1ccc(-c2nn3c(NCCCCNC(=O)CCCC[C@@H]4SC[C@@H]5NC(=O)N[C@@H]54)cccc3c2-c2ccnc(NC3CCCC3)n2)cc1,,CN(C)C=O,,CCN(CC)CC,O,test
US05886014,CNc1ccc(OC)cc1N.COC(=O)COc1ccc(CC2SC(=O)NC2=O)cc1>>COc1ccc2c(c1)nc(COc1ccc(CC3SC(=O)NC3=O)cc1)n2C,,C1COCCO1,,Cl,O=C([O-])O.[Na+],test
US20080293782A1,CS(=O)(=O)Oc1cccc(-c2ccc(OCc3ccccc3)c(N3CC(=O)NS3(=O)=O)c2)c1>>CS(=O)(=O)Oc1cccc(-c2ccc(O)c(N3CC(=O)NS3(=O)=O)c2)c1,[Pd],CCO,CCOC(C)=O,,,test
US20060204985A1,CC(=O)O.CCN(C(C)C)C(C)C>>CC(=O)[O-].CC[NH+](C(C)C)C(C)C,,O,,,,test
US20130261178A1,CC(C)(C)OC(=O)NCCNC(=O)Oc1ccccc1.Cl>>Cl.NCCNC(=O)Oc1ccccc1,,CCOCC,,C1COCCO1,,test
US20040122001A1,Nc1cccc2cc(OS(=O)(=O)C(F)(F)F)ccc12.[I-]>>O=S(=O)(Oc1ccc2c(I)cccc2c1)C(F)(F)F,,Cl,O,O=N[O-].[Na+],,test
US20160168139A1,C=CC(=O)c1cccc(C)n1.COCCN>>COCCNCCC(=O)c1cccc(C)n1,,C1CCOC1,,[Cl-].[NH4+],,test
US20100152165A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)CCc1ccc(N)cc1F>>CCOC(=O)CCc1ccc(NC(=O)OC(C)(C)C)cc1F,,C1COCCO1,,,,test
US05650510,BrBr.CCOP(=O)(COCCn1cnc2c(=O)[nH]c(N)nc21)OCC>>CCOP(=O)(COCCn1c(Br)nc2c(=O)[nH]c(N)nc21)OCC,,O,,,,test
US03953449,O=c1[nH]c2ccccc2c(=O)o1.OCCN1CCN(c2cccc(Cl)c2)CC1>>Nc1ccccc1C(=O)OCCN1CCN(c2cccc(Cl)c2)CC1,,CCOCC,,Cc1ccccc1,,test
US20090131502A1,O=C(c1ccccc1)N1C[C@H](O)[C@@H]2[C@H]1CCN2C(=O)OC1(Cc2ccccc2)CCC1>>O=C1CN(C(=O)c2ccccc2)[C@@H]2CCN(C(=O)OC3(Cc4ccccc4)CCC3)[C@H]12,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20120065214A1,CN.Cc1c(F)cc(C(=O)NC2CC2)cc1-n1ccnc(NC(C)(C)c2ccccc2SCCO)c1=O>>CNCCSc1ccccc1C(C)(C)Nc1nccn(-c2cc(C(=O)NC3CC3)cc(F)c2C)c1=O,,CCO,ClCCl,CCN(CC)CC,CS(=O)(=O)Cl,test
US05677293,CC(C)(C)[Si](C)(C)OC1CC[C@@]2(C)C(=CC[C@@H]3[C@@H]2CC[C@@]2(C)[C@H]3CCC2(O)c2ccoc2)C1>>C[C@]12CC[C@H](O)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3ccoc3)=CC[C@@H]12,,C1COCCO1,,Cl,ClCCl,test
US06350749B1,CC(=O)CCl.Cc1ccc(C2CC(=O)CC(=O)C2)cc1>>Cc1ccc(C2CC(=O)c3c(C)coc3C2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04786649,CC(=O)NCC1CNCC1Cl.O=C(O)c1cn(-c2cccs2)c2cc(F)c(F)cc2c1=O>>CC(=O)NCC1CN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3-c2cccs2)CC1Cl,,CN1CCCC1=O,,,,test
US03989841,C=[N+]=[N-].O=C(O)Cc1ccc2c(c1)Cc1cc(O)ccc1-2>>Cc1c(CC(=O)O)ccc2c1Cc1cc(O)ccc1-2,CC(=O)O,CCOCC,,CO,,test
US20130172556A1,CCc1cc(C)cc(CC)c1-c1c(S(C)(=O)=O)c(C)nn(C)c1=O.[OH-]>>CCc1cc(C)cc(CC)c1-c1c(O)c(C)nn(C)c1=O,,CS(C)=O,,Cl,,test
US04600429,NCCCCCCN.O.O=P(O)(O)CCl>>NCCCCCCNCP(=O)(O)O.O,,O,,,,test
US20090044345A1,CNCc1cc(N(C)C)ccn1.Oc1cc(CCl)nc(-c2cc(Cl)ccn2)c1>>CN(Cc1cc(N(C)C)ccn1)Cc1cc(O)cc(-c2cc(Cl)ccn2)n1,,C1CCOC1,,CCN(CC)CC,,test
US20100048881A1,C1CCOC1.CCCCCCC(C)O.CNS(=O)(=O)c1ccc(C)cc1.COCCOC(=O)N=NC(=O)OCCOC.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CCCCCCC(C)N(C)S(=O)(=O)c1ccc(C)cc1.CCCCCCC(C)O,,C1CCOC1,,,,test
US08618107B2,CN1CCN(c2ccc(N)cn2)CC1.Cn1cc(Br)nc(Br)c1=O>>CN1CCN(c2ccc(Nc3nc(Br)cn(C)c3=O)cn2)CC1,,CC(C)O,,,,test
US20100076046A1,COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)C[C@H](OCCN(C)Cc1ccccc1)COc1ccccc1-3>>CNCCO[C@@H]1COc2ccccc2-c2c(C3CCCCC3)c3ccc(C(=O)OC)cc3n2C1,[Pd],CO,,,,test
US05034417,CC1(c2ccc([N+](=O)[O-])c(Nc3ccc(F)cc3F)c2)OCCO1.CI>>CN(c1ccc(F)cc1F)c1cc(C2(C)OCCO2)ccc1[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],,test
US04922008,Cc1ccc([N+](=O)[O-])cc1.O=S(=O)=O>>Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)O,,O,,O=S(=O)(O)O,,test
US20110195954A1,O=C1Cc2ccccc2N1.O=CC1CC1>>O=C1Nc2ccccc2C1=CC1CC1,,CO,,C1CCNCC1,,test
US20060166985A1,O=S(Cl)Cl.OCc1cc(Cl)ccc1I>>ClCc1cc(Cl)ccc1I,c1ccncc1,O=S(Cl)Cl,,ClCCl,,test
US20080312248A1,ClCCN1CCOCC1.Nc1ccc(O)cc1>>Nc1ccc(OCCN2CCOCC2)cc1,,CN(C)C=O,,Cl,[Na+].[OH-],test
US20120077799A1,CC(C)(C)[Si](C)(C)Oc1ccc(-c2cccnc2N)cc1.O=S(=O)(Cl)CCCl>>CC(C)(C)[Si](C)(C)Oc1ccc(C2=CC=CN3CCS(=O)(=O)N=C23)cc1,,C1CCOC1,,[H-].[Na+],,test
US20140030221A1,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)N1CCC[C@@H](C(=O)OCC(Cl)(Cl)Cl)N1>>CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)N1CCC[C@@H](C(=O)O)N1,[Zn],C1CCOC1,O,C,O=C[O-].[NH4+],test
US20090029994A1,CCNc1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(OCCCC(=O)OCC)cn1.CCOC(=O)Cl>>CCOC(=O)CCCOc1cnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)Cc2cc(C(F)(F)F)ccc2N(CC)C(=O)OCC)nc1,,ClCCl,,c1ccncc1,,test
US20040186160A1,C1COCCN1.O=C(O)CCc1c(/C=C2\C(=O)Nc3ccc(F)cc32)[nH]c2c1CCCCC2>>O=C1Nc2ccc(F)cc2/C1=C/c1[nH]c2c(c1CCC(=O)N1CCOCC1)CCCCC2,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20140142029A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)N(C)C.Cl>>C[C@H](N)C(=O)N(C)C.Cl,,CCOC(C)=O,,,,test
US20110237628A1,CCOC(C)=O.CS(=O)(=O)OCC(c1c2c(nn1-c1ccc(Cl)cc1)CCC2)C1CCCCC1.O=C(NC1CCCCC1)C(c1c2c(nn1-c1ccc(Cl)cc1)CCC2)C1CCCCC1.O=C(O)CC(O)(CC(=O)O)C(=O)O>>COC(=O)c1ccc(OCC(c2c3c(nn2-c2ccc(Cl)cc2)CCC3)C2CCCCC2)nc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20060079555A1,CCN(CC)C(=O)c1ccc(C(Br)=C2CCN(C(=O)OC(C)(C)C)CC2)cc1.O=C(O)c1cccc(B(O)O)c1>>CCN(CC)C(=O)c1ccc(C(=C2CCN(C(=O)OC(C)(C)C)CC2)c2cccc(C(=O)O)c2)cc1,,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20100093757A1,COC(=O)[C@H](CCCO[Si](C)(C)C(C)(C)C)Oc1ncnc2c1cnn2-c1ncccc1Cl.N#Cc1ccc(N)nc1>>CC(C)(C)[Si](C)(C)OCCC[C@H](Oc1ncnc2c1cnn2-c1ncccc1Cl)C(=O)Nc1ccc(C#N)cn1,,Cc1ccccc1,,C[Al](C)C,,test
US20050165028A1,O=C(Nc1ccc2c(c1)OCCO2)c1ccc(Br)cc1.OB(O)c1cccs1>>O=C(Nc1ccc2c(c1)OCCO2)c1ccc(-c2cccs2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20040048865A1,Clc1nc(Cl)c2cccnc2n1.NCc1ccc(Cl)cc1Cl>>Clc1ccc(CNc2nc(Cl)nc3ncccc23)c(Cl)c1,,ClCCCl,O,CCN(C(C)C)C(C)C,,test
US05935953,CN1C2CC=C(C(=O)O)C1CC2.ClC(Cl)Cl.Sc1ccccc1>>COC(=O)[C@@H]1[C@H](Sc2ccccc2)C[C@@H]2CC[C@H]1N2C,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20110306607A1,CC(C)(C)S[Na].CCOC(=O)c1ccc(F)cc1>>CC(C)(C)Sc1ccc(C(=O)O)cc1,,CN(C)C=O,,,,test
US20120208995A1,CCOC(=O)[C@@]12C[C@H]1C=CCCOCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)N2.Fc1cccc2c1CNC2.O=C(n1ccnc1)n1ccnc1>>CCOC(=O)[C@@]12C[C@H]1C=CCCOCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](OC(=O)N3Cc4cccc(F)c4C3)C[C@H]1C(=O)N2,,Cc1ccccc1,,CCN(C(C)C)C(C)C,Cl,test
US20070155839A1,C=CC(=O)OCC.Oc1ccc(C(=C2CCCCCC2)c2ccc(Br)cc2)cc1F>>CCOC(=O)/C=C/c1ccc(C(=C2CCCCCC2)c2ccc(O)c(F)c2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,O,CCN(CC)CC,CN(C)C=O,test
US20020091135A1,CCOC(=O)c1nnc(Cl)s1.Sc1ccccc1>>CCOC(=O)c1nnc(Sc2ccccc2)s1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120245161A1,CC(C)(C)OC(=O)NCc1ccc(OCC(N)=O)c(-c2ccncc2)c1>>CC(C)(C)OC(=O)NCc1ccc(OCC(N)=O)c(C2CCNCC2)c1,O=[Pt]=O,CC(=O)O,CO,,,test
US20150259366A1,COC(=O)c1ccc(N)cc1O.O=Cc1ccc(C2CCCCC2)cc1>>COC(=O)c1ccc(NCc2ccc(C3CCCCC3)cc2)cc1O,,CC(=O)O,O,O=C([O-])O.[Na+],,test
US20120101083A1,CC(C)(C)OC(=O)N1CCc2ccc(-c3noc(-c4ccc(N5CC(F)C5)c(C#N)c4)n3)cc2CC1>>N#Cc1cc(-c2nc(-c3ccc4c(c3)CCNCC4)no2)ccc1N1CC(F)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140296208A1,COc1cc(N)cc(OC)c1Cl>>COc1cc(N)cc(O)c1Cl,,ClCCl,,BrB(Br)Br,,test
US20030114666A1,C[C@@H](c1ccccc1)N1CC(C(=NOCc2ccccc2)c2cocn2)CC1=O>>C[C@@H](c1ccccc1)N1CCC(C(N)c2cocn2)C1,,C1CCOC1,,,,test
US20120196864A1,CN1CCCC1CCN.COc1cc(/C=C2\NC(=O)N=C2N)ccc1Oc1ccc(C#N)cc1C(F)(F)F>>COc1cc(/C=C2\NC(=O)N=C2NCCC2CCCN2C)ccc1Oc1ccc(C#N)cc1C(F)(F)F,,CO,,,,test
US20130217664A1,CCc1cc(O)ccc1Nc1cc2c(cn1)ncn2C.N#CCCl>>CCc1cc(OCC#N)ccc1Nc1cc2c(cn1)ncn2C,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110009519A1,C=C(C)C(=O)OCCC[Si](C)(C)Cl.O>>C=C(C)C(=O)OCCC[Si](C)(C)O,,C1CCOC1,,CCOCC,,test
US04794186,CCOC(=O)C(=NO)C(C)=O.O=C1NCCC1Br>>CCOC(=O)/C(=N\OC1CCNC1=O)C(C)=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04339267,COC(=O)c1ccccc1S(N)(=O)=O.COc1nc(N=C=S)nc2c1CCC2>>COC(=O)c1ccccc1S(=O)(=O)NC(=S)Nc1nc2c(c(OC)n1)CCC2,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100028257A1,CCC(=O)N1C2CCCC1CN(C(=O)OC(C)(C)C)CC2>>CCC(=O)N1C2CCCC1CNCC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080293780A1,COC(=O)c1ccc(OC(F)(F)F)cc1OC>>COc1cc(OC(F)(F)F)ccc1C(=O)O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US04350801,C=CC(N)=O.CC(C)=O.CC(C)=O.NO>>C=CC(N)=NO.CC(C)=O.CC(C)=O,,O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20150368210A1,CC(C)(C)OC(=O)N(Cc1c(Cl)cccc1Cl)c1nc(-c2cccc(CCNC3CCN(C(=O)OC(C)(C)C)[C@@H](C(=O)OC4CCCC4)C3)c2)cnc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>Nc1ncc(-c2cccc(CCNC3CCN[C@@H](C(=O)OC4CCCC4)C3)c2)nc1NCc1c(Cl)cccc1Cl,,C1COCCO1,,Cl,,test
US05686486,O=c1cc(O)c2ccccc2o1.c1ccc([C@H]2O[C@@H]2c2ccccc2)cc1>>O=c1oc2ccccc2c(O)c1C(=Cc1ccccc1)c1ccccc1,,C1COCCO1,,CCOCC,FB(F)F,test
US20150336944A1,CC(C)(C)OC(=O)N(c1cscn1)S(=O)(=O)c1ccc(Oc2cnc(Cl)cc2-c2cncnc2)c(C#N)c1.OB(O)c1cccc(F)c1>>N#Cc1cc(S(=O)(=O)Nc2cscn2)ccc1Oc1cnc(-c2cccc(F)c2)cc1-c1cncnc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,O=C([O-])[O-].[Na+].[Na+],test
US20080318957A1,NCCN.O=C(OCc1ccccc1)C1CC(=O)N(O)C1=O>>NCCNC(=O)OCc1ccccc1,,ClC(Cl)Cl,O,,,test
US05516774,Cc1ccccc1C(=O)Nc1ccc(C(=O)Cl)cc1.c1ccc2c(c1)Cn1cccc1CN2>>Cc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1,,ClCCl,,CCN(CC)CC,,test
US20130324528A1,CCN=C=O.Fc1ccc(F)c(-c2cc(Nc3ccnc4cn[nH]c34)ccn2)c1>>CCNC(=O)n1ncc2nccc(Nc3ccnc(-c4cc(F)ccc4F)c3)c21,,CC#N,,,,test
US20110152299A1,N#Cc1cc(F)cc(F)c1.Oc1cncnc1>>N#Cc1cc(F)cc(Oc2cncnc2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050107334A1,CCSC(=O)OOC(OC(=O)C(C)(C)C)C(C)C.O=S(=O)(Cl)Cl>>CC(C)C(OOC(=O)Cl)OC(=O)C(C)(C)C,,ClCCl,,,,test
US20100160323A1,C1CCNC1.CCOC(=O)c1ccc(Cl)nc1>>CCOC(=O)c1ccc(N2CCCC2)nc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05616712,C#Cc1ccc2c(c1)C(C)(C)CC(=O)N2.CC1(C)CC(=O)Nc2cc(C#C[Si](C)(C)C)ccc21>>C#Cc1ccc2c(c1)NC(=O)CC2(C)C,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20010056094A1,COc1ccc(B(O)O)cc1.O=[N+]([O-])c1cc(Br)ccc1F>>COc1ccc(-c2ccc(F)c([N+](=O)[O-])c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20080194660A1,CCCCc1nc(Cl)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCc1nc(Cl)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nnn(C(c3ccccc3)(c3ccccc3)c3ccccc3)n2)cc1,,ClCCl,,CCN(CC)CC,,test
US20030158245A1,CCOC(=O)c1sc(S(C)(=O)=O)c2c1CCCC2=O.Oc1ccccc1>>CCOC(=O)c1sc(Oc2ccccc2)c2c1CCCC2=O,,C1CCOC1,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20150307464A1,CS(=O)(=O)OCc1nc(C(F)(F)F)ccc1Cl.C[C@@H]1NC(=O)S[C@@H]1c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)SC(=O)N1Cc1nc(C(F)(F)F)ccc1Cl,,C1CCOC1,,[H-].[Na+],,test
US20140080808A1,COc1cccc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO[Si](C)(C)C(C)(C)C)C5)CC3)cc2)n1>>COc1cccc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO)C5)CC3)cc2)n1,,CO,,Cl,,test
US20130065906A1,CCc1cnc(Cl)nc1.O=C(c1ccc(-c2cnco2)cc1)N(C1CCNCC1)C1CC1>>CCc1cnc(N2CCC(N(C(=O)c3ccc(-c4cnco4)cc3)C3CC3)CC2)nc1,,C1COCCO1,CN(C)C=O,CCN(C(C)C)C(C)C,Cl,test
US05356862,CC(C)(C)NS(=O)(=O)c1c(C(=O)O)n(CCOC2CCCCO2)c2ccccc12>>NS(=O)(=O)c1c(C(=O)O)n(CCO)c2ccccc12,,CC(C)=O,,Cl,,test
US05221671,CCOC(C)=O.CCOCCO.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOCCc1cc(S(=O)(=O)O)ccc1C,,c1ccncc1,,,,test
US03968117,CCN(CC)CCCl.CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1cc(N)ccc1Cl>>CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1cc(NCCN(CC)CC)ccc1Cl,,O,,,,test
US04642308,COc1ccc(C(=O)Nc2ccc3ccc(C=O)nc3n2)cc1>>COc1ccc(C(=O)Nc2ccc3ccc(CO)nc3n2)cc1,,CO,,[BH4-].[Na+],,test
US20090143352A1,CN(C)C(=O)c1cc(Cl)nnc1Cl.N>>CN(C)C(=O)c1cc(Cl)nnc1N,,CCO,,,,test
US20100125062A1,OC1CC=C(c2cccnc2F)CC1>>OC1CCC(c2cccnc2F)CC1,[Pd],C1CCOC1,,CCO,,test
US20020004501A1,CCOC(CCN)OCC.O=C=NCCCCl>>CCOC(CCN1CCCNC1=O)OCC,,CCOCC,,[H-].[Na+],,test
US20070099990A1,Brc1ccccc1.Cc1c(C=O)c2c(c(C)c1NC(=O)CC(C)(C)C)C(c1ccc(C(C)C)cc1)CO2>>Cc1c(NC(=O)CC(C)(C)C)c(C)c2c(c1C(O)c1ccccc1)OCC2c1ccc(C(C)C)cc1,,C1CCOC1,,II,[Mg],test
US20130035326A1,Nc1ccc(-c2cnc(NCCN3CCOCC3)nc2)cc1.O=C=Nc1cccc(C(F)(F)F)c1>>O=C(Nc1ccc(-c2cnc(NCCN3CCOCC3)nc2)cc1)Nc1cccc(C(F)(F)F)c1,CN(C)c1ccncc1,CN(C)C=O,,,,test
US20080182868A1,O=C(O)CC(=O)O.O=Cc1ccco1>>O=C(O)C=Cc1ccco1,,O,c1ccncc1,C1CCNCC1,Cl,test
US20040082609A1,CCC(=O)N(c1ccccc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(N)cc2)c2ccccc21.COC(=O)C(C)Br>>COC(=O)C(C)Nc1ccc(C(=O)N2c3ccccc3[C@H](N(C(C)=O)c3ccccc3)C[C@@H]2C)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080269210A1,C[C@@H](O)CSc1cccc(-c2cc3nc(Cl)nc(N4CCOCC4)c3s2)c1.O=S([O-])OO>>C[C@@H](O)CS(=O)(=O)c1cccc(-c2cc3nc(Cl)nc(N4CCOCC4)c3s2)c1,,CO,,O,,test
US20090005558A1,N#Cc1ccc(S(=O)(=O)Cl)cc1.NCCBr>>N#Cc1ccc(S(=O)(=O)NCCBr)cc1,,ClCCl,,Br,CCN(CC)CC,test
US20120238545A1,CCOC(=O)c1nn(-c2ccc[n+]([O-])c2)c2c1CS(=O)(=O)c1ccccc1-2>>CCOC(=O)c1nn(-c2cccnc2)c2c1CS(=O)(=O)c1ccccc1-2,[Fe],CC(=O)O,O,,,test
US20090306076A1,O=C1CCCCc2ccc(Br)cc21>>OC1CCCCc2ccc(Br)cc21,,CCO,,[BH4-].[Na+],,test
US20120168730A1,Brc1ccc2c(c1)Cc1cc(-c3ccccc3)ccc1N2c1ccc(-c2ccccc2)cc1.CC1(C)OB(c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccccc4)cc3)cc2)OC1(C)C>>c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccc5c(c4)Cc4cc(-c6ccccc6)ccc4N5c4ccc(-c5ccccc5)cc4)cc3)cc2)cc1,,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20050070583A1,CCc1cc(SCC=C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)ccc1OCC(=O)OC>>CCc1cc(SCC=C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)ccc1OCC(=O)O,,CCO,,Cl,[Na+].[OH-],test
US20150045356A1,CCCCCCOC(=O)Cl.O=c1ccc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc2[nH]1>>CCCCCCOC(=O)Oc1ccc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc2n1,,ClCCl,,CCN(CC)CC,O,test
US20150119405A1,COC(=O)C1C[C@@H](N)[C@H](O)C1.COc1cc(OC)c(Cl)c(-c2ccc3nc(Cl)ncc3c2)c1Cl>>COC(=O)[C@H]1C[C@@H](Nc2ncc3cc(-c4c(Cl)c(OC)cc(OC)c4Cl)ccc3n2)[C@H](O)C1,,CC#N,CCOC(C)=O,C1CCC2=NCCCN2CC1,,test
US20060149062A1,CC(C)Sc1ccc([N+](=O)[O-])cc1C(=O)O.FC(F)(F)c1ccc(N2CCNCC2)cc1>>CC(C)Sc1ccc([N+](=O)[O-])cc1C(=O)N1CCN(c2ccc(C(F)(F)F)cc2)CC1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20150031730A1,CN(O)C(=N)/C(=N\OCc1csc(N)n1)c1ccccc1.O=C(Cl)Oc1ccc(F)cc1>>Cn1oc(=O)nc1/C(=N\OCc1csc(N)n1)c1ccccc1,,CN(C)C=O,,CCN(CC)CC,,test
US20130059833A1,BrC(Br)(Br)Br.Cc1cn(-c2ccccc2)nc1CO>>Cc1cn(-c2ccccc2)nc1CBr,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US05610144,CC(C)(C)OC(=O)[C@@H]1CC[C@H](c2c[nH]c3ccccc23)N1C(=O)CNC(=O)Nc1cccc(C(=O)OCC[Si](C)(C)C)c1>>CC(C)(C)OC(=O)[C@@H]1CC[C@H](c2c[nH]c3ccccc23)N1C(=O)CNC(=O)Nc1cccc(C(=O)O)c1,,CCOC(C)=O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05559127,CC(C)(C)OC(=O)N1CCC(CCCC=C(Br)Br)CC1>>C#CCCCC1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,[Li]CCCC,,test
US20140031360A1,CC(C)(C)OC(=O)N1CCC[C@@H](Oc2cncc(-c3c[nH]c4ccc(-c5c(F)cccc5F)cc34)n2)C1>>Fc1cccc(F)c1-c1ccc2[nH]cc(-c3cncc(O[C@@H]4CCCNC4)n3)c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070208001A1,O=C(NC1CCCCC1)[C@H]1CCC[C@@H](O)C1.Oc1ccc(Cl)cc1>>O=C(NC1CCCCC1)C1CCCC(Oc2ccc(Cl)cc2)C1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080312272A1,CC(C#N)(Cn1nc2cc(Cl)cc(C=O)c2n1)NC(=O)c1ccc(OC(F)(F)F)cc1>>CC(C#N)(Cn1nc2cc(Cl)cc(CO)c2n1)NC(=O)c1ccc(OC(F)(F)F)cc1,,CCO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20080182854A1,C1COCCN1.Cc1cccc(C(=O)O)n1>>Cc1cccc(C(=O)N2CCOCC2)n1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20150105404A1,Cn1ccnn1.Cn1cncc1C=O>>Cn1cncc1C(O)c1cnnn1C,,C1CCOC1,,[Li]CCCC,,test
US20100010053A1,N#Cc1ccc2[nH]c(CO)cc2c1>>N#Cc1ccc2[nH]c(C=O)cc2c1,O=[Mn]=O,ClCCl,,,,test
US20040259877A1,Nc1ccccc1O.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>O=C(Nc1ccccc1O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,ClCCl,c1ccncc1,Cl,[Na+].[OH-],test
US20080153868A1,CC(C)[Si](Oc1cccc2c1CN(C(=O)OC(C)(C)C)C([C@@H](O)[C@H](Cc1cc(F)cc(F)c1)C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1)C2)(C(C)C)C(C)C.OO>>CC(C)[Si](Oc1cccc2c1CN(C(=O)OC(C)(C)C)C([C@@H](O)[C@H](Cc1cc(F)cc(F)c1)C(=O)O)C2)(C(C)C)C(C)C,,C1CCOC1,O,[Li+].[OH-],,test
US20100093694A1,CC(C)CN.CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)O)ccc3OC)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NCC(C)C)ccc3OC)cc12,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060252812A1,CCCCCCN1C(=O)C(c2cc3c(cc2O)OCO3)c2ccccc21.CCOC(=O)CBr>>CCCCCCN1C(=O)C(CC(=O)OCC)(c2cc3c(cc2O)OCO3)c2ccccc21,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20140200216A1,C[C@H]1CN(c2ccncc2NC(=O)c2nc3cc(C4=CCN(C)CC4)ccc3cc2NC(=O)OCc2ccccc2)C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C>>C[C@H]1CN(c2ccncc2NC(=O)c2nc3cc(C4CCN(C)CC4)ccc3cc2N)C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C,[Pd],CO,,[H][H],,test
US20100137245A1,CC(C)(C)OC(=O)N1CCC(c2nc(C=O)cs2)CC1.COP(=O)(OC)C(=[N+]=[N-])C(C)=O>>C#Cc1csc(C2CCN(C(=O)OC(C)(C)C)CC2)n1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20100069448A1,CCCCOC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc([N+](=O)[O-])cc1)c1nc(CC)cs1.COC(=O)Cl>>CCc1csc([C@H](Cc2ccc([N+](=O)[O-])cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)OC)n1,,C1COCCO1,Cl,O,,test
US20060052378A1,CC(=O)Cl.O=C(O)c1cc2ccccc2[nH]1>>O=C(Cl)c1cc2ccccc2[nH]1,,CCOCC,,ClP(Cl)(Cl)(Cl)Cl,,test
US20070244159A1,COC(=O)C1(c2ccc(O)c([N+](=O)[O-])c2)CC1>>COC(=O)C1(c2ccc(O)c(N)c2)CC1,[Ni],CO,,,,test
US20110020278A1,CC1CCC(C(=O)N(c2cc(C#CC(C)(C)C)sc2C(=O)O)C2CCC(Oc3nccc(OCC[Si](C)(C)C)n3)CC2)CC1>>CC1CCC(C(=O)N(c2cc(C#CC(C)(C)C)sc2C(=O)O)C2CCC(Oc3nccc(=O)[nH]3)CC2)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110269956A1,CC(C)(C)OC(=O)N1CCC[C@H]1c1nc2ccc(-c3ccc4cc(-c5ccc(-c6cnc([C@@H]7CCCN7C(=O)OCc7ccccc7)[nH]6)cc5)ccc4c3)cc2[nH]1.CC(C)(C)OC(=O)N1CCC[C@H]1c1nc2ccc(-c3ccc4ccc(-c5ccc(-c6cnc([C@@H]7CCCN7C(=O)OCc7ccccc7)[nH]6)cc5)cc4c3)cc2[nH]1.O=C(OCc1ccccc1)N1CCC[C@H]1c1ncc(-c2ccc(-c3ccc4cc(-c5ccc6nc([C@@H]7CCCN7)[nH]c6c5)ccc4c3)cc2)[nH]1>>O=C(OCc1ccccc1)N1CCC[C@H]1c1ncc(-c2ccc(-c3ccc4ccc(-c5ccc6nc([C@@H]7CCCN7)[nH]c6c5)cc4c3)cc2)[nH]1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04479949,CC(=O)N1c2ccccc2SC1c1ccccc1O.CCOC(=O)CCCCl>>CCOC(=O)CCCOc1ccccc1C1Sc2ccccc2N1C(C)=O,,CN(C)C=O,,[H-].[Na+],,test
US20160200703A1,CC(C)(C)OC(=O)Nc1ccc(/C=C/C(=O)OCc2ccccc2)cc1>>Nc1ccc(/C=C/C(=O)OCc2ccccc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100113512A1,CCOC(CNC(=N)c1cccc(Br)c1)OCC>>Brc1cccc(-c2ncc[nH]2)c1,,O=CO,,,,test
US07423037B2,COc1ccc(F)cc1CC(O)(C1CCOCC1)C1CN(Cc2ccccc2)CCO1.Cl>>COc1ccc(F)cc1CC(O)(C1CCOCC1)C1CNCCO1.Cl,,CC(C)O,,O,,test
US05770595,C=CCCCCCCCCCCn1c(=O)c2c(ncn2C)n(C)c1=O.C[N+]1([O-])CCOCC1.O>>Cn1cnc2c1c(=O)n(CCCCCCCCCCC(O)CO)c(=O)n2C,,CC(C)=O,O,O=S([O-])[O-].[Na+].[Na+],,test
US05206235,BrCc1ccccc1.C=CC(C)(C)O>>C=CC(C)(C)OCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20130338137A1,CC1(C)C(=O)Nc2nc(-c3nc(Cc4ccccc4F)c4ncccn34)nc(I)c21.NCCC(F)(F)F>>CC1(C)C(=O)Nc2nc(-c3nc(Cc4ccccc4F)c4ncccn34)nc(NCCC(F)(F)F)c21,,CN1CCCC1=O,,,,test
US05591762,CCCc1nc2c(C)cc(-c3coc(C)n3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1.CNC=O.O>>CCCc1nc2c(C)cc(-c3cn(C)c(C)n3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1.O,,CC(=O)O,,CN,,test
US20120010228A1,CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(CCCN4C(=O)COc5ccccc54)CC3)C2=O)c1>>O=C(O)c1cccc(CN2CN(c3ccccc3)C3(CCN(CCCN4C(=O)COc5ccccc54)CC3)C2=O)c1,,C1COCCO1,,Cl,,test
US20080176832A1,CS(=O)(=O)Nc1ccc(-n2cc3c(n2)CCNCC3)cc1.O=C1CCC1>>CS(=O)(=O)Nc1ccc(-n2cc3c(n2)CCN(C2CCC2)CC3)cc1,CC(=O)O,CO,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20050059650A1,CC(C)(C)OC(=O)N1CCC(Oc2ncnc(Nc3ccc(S(C)(=O)=O)cc3)c2N)CC1.CCOC(OCC)OCC>>CC(C)(C)OC(=O)N1CCC(Oc2ncnc3c2ncn3-c2ccc(S(C)(=O)=O)cc2)CC1,,CC(=O)OC(C)=O,,,,test
US20040006119A1,Nc1ccc(F)cc1N.S=C=Nc1cscc1Cl>>Nc1cc(F)ccc1NC(=S)Nc1cscc1Cl,,C1CCOC1,,,,test
US20070191333A1,CS(=O)(=O)Cl.OC1CCN(Cc2ccccc2)C1>>CS(=O)(=O)O[C@H]1CCN(Cc2ccccc2)C1,,ClCCl,,CCN(CC)CC,,test
US20100310512A1,CON(C)C(=O)C1=CC2SC=CC2S1.C[Mg]Br>>CC(=O)C1=CC2SC=CC2S1,,C1CCOC1,,,,test
US20110003787A1,COC[C@H](C)Oc1cc(O)cc(-c2ccc(-c3nccs3)n2C(=O)OC(C)(C)C)c1.O=S(=O)(c1ccc(F)cc1)N1CCC1>>COC[C@H](C)Oc1cc(Oc2ccc(S(=O)(=O)N3CCC3)cc2)cc(-c2ccc(-c3nccs3)[nH]2)c1,,CN1CCCC1=O,,O,[H-].[Na+],test
US20140031355A1,CC(C)(C)S(=O)/N=C/c1ccc2cccnc2c1-c1cc(F)cc(F)c1.C[Mg]Br>>CC(NS(=O)C(C)(C)C)c1ccc2cccnc2c1-c1cc(F)cc(F)c1,,C1CCOC1,O,CCOCC,[Cl-].[NH4+],test
US20150336962A1,CCOC(=O)CN(CCn1cc(NC(=O)c2cnn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1)Cc1cccnc1>>O=C(O)CN(CCn1cc(NC(=O)c2cnn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1)Cc1cccnc1,,CCO,,Cl,[Na+].[OH-],test
US20100285145A1,CC(C)(C)OC(=O)N1CCc2cc(SCCO)ccc21>>OCCSc1ccc2c(c1)CCN2,,C1COCCO1,,Cl,,test
US20130203727A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2ccccc2c1C1=CCCCC1>>Cc1cc2ccccc2c(C2=CCCCC2)c1[C@H](OC(C)(C)C)C(=O)O,,CCO,CCOC(C)=O,[Na+].[OH-],,test
US06492416B1,CC1(C)OC(c2ccc(S(N)(=O)=O)cc2)=C(I)C1=O.OB(O)c1cccc(C(F)(F)F)c1>>CC1(C)OC(c2ccc(S(N)(=O)=O)cc2)=C(c2cccc(C(F)(F)F)c2)C1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20080146569A1,COC(=O)c1ccc(-c2ccccc2O)nc1>>O=C(O)c1ccc(-c2ccccc2O)nc1,,C1COCCO1,,CC(=O)O,[Na+].[OH-],test
US04728355,CC(C)N.O=C(Nc1cnnc(Cl)c1Cl)Oc1ccccc1>>CC(C)NC(=O)Nc1cnnc(Cl)c1Cl,,C1CCOC1,,,,test
US20110028450A1,CS(=O)(=O)Cl.OCCSCC#Cc1cccs1>>CS(=O)(=O)OCCSCC#Cc1cccs1,,CCOCC,,CCN(CC)CC,,test
US20100305166A1,COC(=O)c1ccc(CNC(=O)c2cc(OCc3ccccc3Cl)ccc2Cl)cc1>>O=C(O)c1ccc(CNC(=O)c2cc(OCc3ccccc3Cl)ccc2Cl)cc1,,CC(=O)O,Cl,,,test
US20070249580A1,COC(=O)c1ccccc1F.Cc1nc(-c2ccc(Cl)cc2)sc1C(=O)NCC1CCCNC1>>COC(=O)c1ccccc1N1CCCC(CNC(=O)c2sc(-c3ccc(Cl)cc3)nc2C)C1,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20060094767A1,CC(O)(CO)Cn1cc([N+](=O)[O-])nc1Cl.O=C(Cl)N1CC=C(c2ccc(C(F)(F)F)cc2)CC1>>CC(O)(COC(=O)N1CC=C(c2ccc(C(F)(F)F)cc2)CC1)Cn1cc([N+](=O)[O-])nc1Cl,CN(C)c1ccncc1,CCOC(C)=O,Cc1ccccc1,CCN(C(C)C)C(C)C,,test
US20160221973A1,COC(=O)c1ccc(CN[C@H](CO)c2cccc(Cl)c2)c(Br)c1>>COC(=O)c1ccc2c(c1)OC[C@H](c1cccc(Cl)c1)NC2,[Cu]I,CC(C)O,,Cl,O=C([O-])[O-].[K+].[K+],test
US05298627,CC1(C)O[C@H](CC#N)C[C@H](CC(=O)N(Cc2ccccc2)Cc2ccccc2)O1>>CC1(C)O[C@H](CCN)C[C@H](CC(=O)N(Cc2ccccc2)Cc2ccccc2)O1,[Ni],CO,,N,[H][H],test
US20070299051A1,Cc1cc(C(=O)O)cc2c1Oc1c(Cl)cc(N)cc1CS2(=O)=O.ClCCl.O=C(Cl)CCl>>COC(=O)c1cc(C)c2c(c1)S(=O)(=O)Cc1cc(NC(=O)CCl)cc(Cl)c1O2,,ClCCl,,c1ccncc1,,test
US20120202776A1,CN1CCN(N)CC1.CP(C)(=O)c1ccc(Nc2ncc(C(F)(F)F)c(Cl)n2)cc1>>CN1CCN(Nc2nc(Nc3ccc(P(C)(C)=O)cc3)ncc2C(F)(F)F)CC1,,CCO,,CCN(CC)CC,,test
US20140088071A1,Fc1ccccc1Cn1nc(-c2ccccn2)nc1Br.c1cn[nH]c1>>Fc1ccccc1Cn1nc(-c2ccccn2)nc1-n1cccn1,,CN(C)C=O,,O,[H-].[Na+],test
US20130143843A1,CCCCOc1ccc(C(C)(CC(=O)OC)NS(=O)C(C)(C)C)cc1>>CCCCOc1ccc(C(C)(N)CC(=O)OC)cc1,,CO,,Cl,,test
US20110281969A1,C1CCNCC1.O=C=NC1CCCCC1>>O=C(NC1CCCCC1)N1CCCCC1,,CCCCCC,,,,test
US04002640,Nc1ccc(S(=O)Cc2ccccc2)cc1[N+](=O)[O-]>>Nc1ccc(S(=O)Cc2ccccc2)cc1N,[Fe],O,,CO,,test
US20100278833A1,CC(Oc1cc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)sc1C(N)=O)c1ccc(C#N)cc1Cl>>CC(Oc1cc(-n2cnc3cnc(CO)cc32)sc1C(N)=O)c1ccc(C#N)cc1Cl,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05030270,CCS(=O)(=O)CCCl.CN>>CCS(=O)(=O)CCNC,,Cc1ccccc1,,,,test
US20130158025A1,CCCCc1n[nH]c(N)c1-c1ccc(C)cc1.CCOC(=O)CC(=O)c1ccc(F)cc1>>CCCCc1nn2c(-c3ccc(F)cc3)cc(=O)[nH]c2c1-c1ccc(C)cc1,,c1ccncc1,,,,test
US20150111887A1,CC(C)(C)OC(=O)N1CCN(c2ncc(Br)cn2)CC1.CC(C)(C)[S@@](=O)/N=C(/c1ccc(F)cc1)C(F)(F)F>>CC(C)(C)OC(=O)N1CCN(c2ncc([C@@](N[S@](=O)C(C)(C)C)(c3ccc(F)cc3)C(F)(F)F)cn2)CC1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20060229341A1,CCCCCC(CO)C(=O)NOCc1ccccc1>>CCCCCC1CN(OCc2ccccc2)C1=O,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04939137,COC(=O)c1cscc1N.O=C=NCCCCCBr>>COC(=O)c1cscc1NC(=O)NCCCCCBr,,Cc1ccccc1,,,,test
US20100113421A1,Cc1[nH]c(C(=O)OC(C)(C)C)c(C(C)C)c1C(=O)OCc1ccccc1>>Cc1[nH]c(C(=O)OC(C)(C)C)c(C(C)C)c1C(=O)O,[Pd],CO,,[H][H],,test
US20040132727A1,CC1CCCCN1CCCN.COc1cc2nccc(Oc3ccc(N)c(C)c3C)c2cc1OC.S=C(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=S)NCCCN4CCCCC4C)c(C)c3C)c2cc1OC,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,,test
US20130165483A1,BrCC1CC1.COC(=O)c1cc(Br)c[nH]1>>O=C(O)c1cc(Br)cn1CC1CC1,,C1CCOC1,CN(C)C=O,CC(C)(C)[O-].[K+],,test
US06486155B1,CCOC(=O)C(Br)C(=O)OCC.COc1cc(C(=O)O)c(C(=O)c2cc(OC)c(OC)c(OC)c2)cc1OC>>COc1cc2c(-c3cc(OC)c(OC)c(OC)c3)c(C(=O)O)oc(=O)c2cc1OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04695582,CC(C)(C)OC(=O)[C@@H]1CCCN1C(=O)CCSC(=O)[C@@H](N)Cc1cccc(C(=O)c2ccccc2)c1>>N[C@@H](Cc1cccc(C(=O)c2ccccc2)c1)C(=O)SCCC(=O)N1CCC[C@H]1C(=O)O,,COc1ccccc1,,O=C(O)C(F)(F)F,,test
US20040127465A1,CCOP(N)(=O)Cc1cc(Cl)ccc1O.C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](C)CN1C(=O)CO>>CCOP(N)(=O)Cc1cc(Cl)ccc1OCC(=O)N1CC(C)N(Cc2ccc(F)cc2)CC1C,,Cc1ccccc1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070259854A1,BrCCCCBr.N#CCC1=CCCCC1>>N#CC1(C2=CCCCC2)CCCC1,,CN(C)C=O,,[H-].[Na+],,test
US20040214832A1,COc1ccccc1COCCCOc1ccc(N2C(=O)CN(C(=O)OC(C)(C)C)C[C@@H]2COC(=O)c2ccc3ccccc3c2)cc1>>COc1ccccc1COCCCOc1ccc(N2C(=O)CNC[C@@H]2COC(=O)c2ccc3ccccc3c2)cc1,,CO,,CC(=O)Cl,,test
US20130217668A1,CC(C)NC(=O)[C@H]1CC[C@@H](Nc2cc(F)ccc2[N+](=O)[O-])CC1>>CC(C)NC(=O)[C@@H]1CC[C@H](Nc2cc(F)ccc2N)CC1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20120094986A1,CCNc1nc(Cl)ccc1C(=O)O.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCn1c(=O)oc(=O)c2ccc(Cl)nc21,,C1COCCO1,,,,test
US07396844B1,BrCc1ccccc1.N#Cc1cccc(OCCNC(=O)CC2CCNCC2)c1>>N#Cc1cccc(OCCNC(=O)CC2CCN(Cc3ccccc3)CC2)c1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20070093521A1,CCOc1cc(C=O)cc(OCC)c1-c1ccc(F)cc1.OCc1nccc2nc(NC3CCNCC3)oc12>>CCOc1cc(CN2CCC(Nc3nc4ccnc(CO)c4o3)CC2)cc(OCC)c1-c1ccc(F)cc1,,CC(=O)O,CCO,CCN(C(C)C)C(C)C,[BH3-]C#N.[Na+],test
US20090197871A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CN>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100137394A1,CC(C)(C)OC(=O)N1CCC(c2ccc(NS(C)(=O)=O)cc2)=N1.O=C(O)C(F)(F)F>>CS(=O)(=O)Nc1ccc(C2=NNCC2)cc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US05977125,CC1(C)CCC(C)(C)C(=O)C1=O.NC1CCCCC1N>>CC1(C)CCC(C)(C)c2nc3c(nc21)CCCC3,,CC(=O)O,,O,,test
US20030166639A1,CNCC(C)C.Cc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3ccnc(CO)c3)c1)=N2>>Cc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3ccnc(CN(C)CC(C)C)c3)c1)=N2,,ClCCl,,O=S(Cl)Cl,,test
US20040126812A1,CC(C)(C)[Si](C)(C)Cl.O=C(CCCC(O)c1ccccc1)N1C(=O)OCC1c1ccccc1>>CC(C)(C)[Si](C)(C)OC(CCCC(=O)N1C(=O)OCC1c1ccccc1)c1ccccc1,,CN(C)C=O,,c1c[nH]cn1,,test
US20150126761A1,CC(=O)[O-].CCCCCC.CCOC(C)=O.CO.[OH-]>>O=C(O)COc1ccccc1,,CCOC(C)=O,CO,Cl,,test
US20150291582A1,Cc1cc(Cn2cc3c(C(=O)NCCNC(=O)OC(C)(C)C)nccc3n2)cnc1OCC(F)(F)F.Cl>>Cc1cc(Cn2cc3c(C(=O)NCCN)nccc3n2)cnc1OCC(F)(F)F.Cl,,C1COCCO1,,,,test
US06479531B1,C1COCCO1.CC(C)(C)C=O.CN(C)c1ccccc1C=O.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Cc1ccc(N)cc1C(=O)OCc1ccccc1.Nc1cccc(C(=O)OCc2ccccc2)c1>>Cc1ccc(NC(=O)c2nc(C(C)(C)C)[nH]c2CCC23CC4CC(CC(C4)C2)C3)cc1C(=O)O,,O,,,,test
US20080167353A1,NO.O=C1OC(=O)c2c1cc1ccc3c(c1c2-c1ccc2c(c1)OCO2)OCO3>>O=C1c2cc3ccc4c(c3c(-c3ccc5c(c3)OCO5)c2C(=O)N1O)OCO4,,CCO,,CCN(CC)CC,Cl,test
US20100010037A1,ON=Cc1c[nH]c2ncccc12>>N#Cc1c[nH]c2ncccc12,,CC(=O)OC(C)=O,,O,,test
US20100087429A1,CC(C)(C)CI.NC1=N[C@@]2(CO1)c1cc(-c3cccnc3)ccc1Oc1ccc(O)c(Br)c12>>CC(C)(C)COc1ccc2c(c1Br)[C@]1(COC(N)=N1)c1cc(-c3cccnc3)ccc1O2,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05180419,CC(C)C1(C)N=C(c2c(C(=O)O)ccc3c2OCO3)NC1=O>>CC(C)C1(C)C(=O)N=C2c3c(ccc4c3OCO4)C(=O)N21,,Cc1ccccc1,,CC(=O)OC(C)=O,,test
US20110124634A1,CCOC(=O)Cc1c(Cl)nc(N)nc1Cl.COc1cc(CN)c(Cl)c(OC)c1OC>>CCOC(=O)Cc1c(Cl)nc(N)nc1NCc1cc(OC)c(OC)c(OC)c1Cl,,CCO,,CCN(CC)CC,,test
US20130158003A1,Cn1cc(-c2ccccc2)nc1C=Cc1cccc(Br)n1.c1c[nH]cn1>>Cn1cc(-c2ccccc2)nc1C=Cc1cccc(-n2ccnc2)n1,[Cu]I,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150057238A1,COC(=O)C1C(C)C1C(=O)O.O=C(Cl)C(=O)Cl>>COC(=O)C1C(C)C1C(=O)Cl,CN(C)C=O,ClCCl,,,,test
US20110160198A1,COC(=O)[C@H](Cc1ccc(-c2ccnc(C)c2C)cc1)NC(=O)[C@@H]1Cc2cc3c(cc2CN1)O[C@@H](c1ccc(OCC2CCCCC2)cc1)CO3.C[C@@H](N=C=O)c1ccccc1>>Cc1nccc(-c2ccc(C[C@H](NC(=O)[C@@H]3Cc4cc5c(cc4CN3C(=O)N[C@H](C)c3ccccc3)O[C@@H](c3ccc(OCC4CCCCC4)cc3)CO5)C(=O)O)cc2)c1C,,ClCCl,,,,test
US04009208,C=CCOc1ccc(C(=O)OCC)cc1>>C=CCOc1ccc(C(=O)O)cc1,,O,,[K+].[OH-],,test
US05013841,CCOC(=O)c1cn(C2CC2)c2cc(F)c(F)c(F)c2c1=O>>O=C(O)c1cn(C2CC2)c2cc(F)c(F)c(F)c2c1=O,,O,,CC(=O)O,O=S(=O)(O)O,test
US06255496B1,COc1ccc(CCC(=O)O)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccc(CCC(=O)C(F)(F)F)cc1,,ClCCl,,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20010053853A1,CCOC(=O)CC(CCCCCCCNC(=O)OC(C)(C)C)c1cnc(C)nc1>>CCOC(=O)CC(CCCCCCCN)c1cnc(C)nc1,,CCOC(C)=O,,Cl,,test
US20120046292A1,CC(C)(C)OC(=O)CC1CCC(c2ccc(C(=O)NCCNC(=O)c3ccc(Cl)cc3)cc2)CC1>>O=C(O)CC1CCC(c2ccc(C(=O)NCCNC(=O)c3ccc(Cl)cc3)cc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090275570A1,CC(C)(C)[Si](C)(C)OCc1ncccc1O>>CC(C)(C)[Si](C)(C)OCC1NCCCC1O,O=[Pt]=O,O,,CCO,,test
US04105762,CCCCC(COS(C)(=O)=O)c1ccc(Cl)cc1Cl.O=[N+]([O-])c1c[nH]cn1>>CCCCC(Cn1cnc([N+](=O)[O-])c1)c1ccc(Cl)cc1Cl,,CO,,O,[Na+].[OH-],test
US20120142625A1,COC(=O)CC1CC(=O)C1.COc1ccc(CNc2ncnc3c2ccn3[C@@H]2O[C@H](CN)[C@H]3OC(C)(C)O[C@H]32)c(OC)c1>>COC(=O)CC1CC(NC[C@H]2O[C@@H](n3ccc4c(NCc5ccc(OC)cc5OC)ncnc43)[C@@H]3OC(C)(C)O[C@@H]32)C1,,ClCCCl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20050234057A1,CC(=O)OC/C=C\COC(C)=O.CCN(CC)CC.Nc1ccccc1N1CCC(NC(=O)C2(NC(=O)c3cc4ccccc4o3)CCCCC2)C(O)C1>>O=C(NC1(C(=O)NC2CCN(c3ccccc3NN3CC=CC3)CC2O)CCCCC1)c1cc2ccccc2o1,,CN(C)C=O,ClCCl,,,test
US04473393,O=C(O)CNc1ccccc1.S=C=NCc1ccccc1>>O=C1CN(c2ccccc2)C(=S)N1Cc1ccccc1,,Cc1ccccc1,,,,test
US20100305093A1,CCN(C(C)C)C(C)C.CCOC(=O)c1ccc(-c2ccc3c(c2)CNCCO3)cc1.Cc1c(C(=O)O)ccc(S(C)(=O)=O)c1F>>CCOC(=O)c1ccc(-c2ccc3c(c2)CN(C(=O)c2ccc(S(C)(=O)=O)c(F)c2CC)CCO3)cc1,,CN(C)C=O,,Cl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110217245A1,COC(COCCC(C)(C)OC)OC>>COC(C)(C)CCOCC=O,,O,,O=CO,,test
US20100184758A1,CC(C)(C)OC(=O)NC(Cc1c[nH]c2cc(F)ccc12)c1nc(-c2cc(F)ccn2)c[nH]1.O=CC1CCOCC1>>Fc1ccc(-c2c[nH]c(C3Cc4c([nH]c5cc(F)ccc45)C(C4CCOCC4)N3)n2)nc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080004295A1,CCCN(C)C(=O)c1ccc([N+](=O)[O-])cc1>>CCCN(C)C(=O)c1ccc(N)cc1,[Pd],CCO,,,,test
US20090215770A1,CC(C)(C)OC(=O)N1CCC[C@@H]1CO.COc1cc(C#N)c(N=CN(C)C)cc1O>>COc1cc(C#N)c(/N=C/N(C)C)cc1OC[C@H]1CCCN1C(=O)OC(C)(C)C,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05158950,CCOC(=O)OC(=O)C(C(=O)OC(C)C)=C1SC=CS1.N>>CC(C)OC(=O)C(C(N)=O)=C1SC=CS1,,CC#N,,,,test
US20120294835A1,Cl.Clc1cc(Cl)ncn1.Nc1cccc([N+](=O)[O-])c1>>Cl.O=[N+]([O-])c1cccc(Nc2cc(Cl)ncn2)c1,,CC(C)O,,,,test
US20110059943A1,CCc1nc(Nc2nc3c(cc(C(=O)N(C4CC4)C4CC4)n3CC)c3c2ncn3C)sc1C(=O)OC>>CCc1nc(Nc2nc3c(cc(C(=O)N(C4CC4)C4CC4)n3CC)c3c2ncn3C)sc1C(=O)O,,CO,O,Cl,[Na+].[OH-],test
US06251890B1,NS(=O)(=O)c1ccc2c3c(ccc([N+](=O)[O-])c13)CNC2>>O=S1(=O)Nc2ccc3c4c(ccc1c24)CNC3,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150210647A1,CN(C)C=O.FC(F)(F)[C@@H]1CC[C@H](Oc2ccc3ccc(Br)cc3c2)CC1>>O=Cc1ccc2ccc(O[C@H]3CC[C@@H](C(F)(F)F)CC3)cc2c1,,C1CCOC1,,[Li]CCCC,,test
US05668161,CC(C)(C)NC(N)=S.CS(=O)(=O)c1ccc(C(Br)C(=O)c2ccc(F)cc2)cc1>>CC(C)(C)Nc1nc(-c2ccc(F)cc2)c(-c2ccc(S(C)(=O)=O)cc2)s1,,CCO,,,,test
US06689806B1,CC(C)c1ccc(O)cc1.O=C1Cc2c(CCO)cccc2N1>>CC(C)c1ccc(OCCc2cccc3c2CC(=O)N3)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150065510A1,COC(=O)c1ncccc1C(=O)c1cccnc1.NN>>O=c1[nH]nc(-c2ccccn2)c2ncccc12,,CCO,,O,,test
US20060142265A1,CCCOc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)CNC(C)(C)C(=O)N3)cccc1OC.Cl>>CCCOc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)CNC(C)(C)C(=O)N3)cccc1OC.Cl,,CCOCC,ClCCl,,,test
US20130116213A1,C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)cc3)nc3ccsc23)c1>>C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCNCC4)cc3)nc3ccsc23)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100331320A1,CC(N)=O.C[C@@H](c1ccc(-c2ccc(=O)n(C)c2)cc1)N1CC[C@](CC(C)(C)C#N)(c2ccccc2)OC1=O>>C[C@@H](c1ccc(-c2ccc(=O)n(C)c2)cc1)N1CC[C@](CC(C)(C)C(N)=O)(c2ccccc2)OC1=O,Cl[Pd]Cl,O,,C1CCOC1,,test
US20120088755A1,COCCC(=O)O.Cc1cc(O)cc(N)c1N>>COCCc1nc2c(C)cc(O)cc2[nH]1,,CO,,[Na+].[OH-],,test
US20090181928A1,C[Si](C)(C)CCN1C(=O)CN(c2ccc(CCNC(=O)c3ccccc3)cc2OCc2ccccc2)S1(=O)=O>>O=C1CN(c2ccc(CCNC(=O)c3ccccc3)cc2OCc2ccccc2)S(=O)(=O)N1,,C1CCOC1,,Cl,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US04837242,CC1=CC(C)(C(=O)Nc2cccc3c2C(C)CC3(C)C)NN1C.CSP1(=S)SP(=S)(SC)S1>>CC1=CC(C)(C(=S)Nc2cccc3c2C(C)CC3(C)C)NN1C,,COCCOC,,,,test
US20150291573A1,CI.O=S(=O)(c1cccc(C(F)(F)F)c1)C1CCOC(c2cc(Br)ccc2Br)C1>>CC1(S(=O)(=O)c2cccc(C(F)(F)F)c2)CCOC(c2cc(Br)ccc2Br)C1,,C1CCOC1,CCOC(C)=O,CC(C)(C)[O-].[K+],,test
US06015897,CCN(CC)CC.CNCC(=O)OC.O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21>>COC(=O)CN(C)NC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21,,CN(C)C=O,,,,test
US20110294807A1,Nc1ccc(Br)cc1.O=c1[nH]c2c(Cl)cccc2c(=O)o1>>Nc1c(Cl)cccc1C(=O)Nc1ccc(Br)cc1,,O,,CN(C)C=O,,test
US20080312231A1,COC(=O)CC1CCCN1.O=S(=O)(Cl)c1ccc(Cl)c(Cl)c1>>COC(=O)CC1CCCN1S(=O)(=O)c1ccc(Cl)c(Cl)c1,,CCN(CC)CC,ClCCl,Cl,,test
US20110269765A1,Clc1ccc(Oc2ccccc2)nn1.O=CO>>O=c1ccc(Oc2ccccc2)n[nH]1,,O=CO,,O,[Na+].[OH-],test
US20160272633A1,BrCc1ccccc1.COc1ccnc(O)c1C#N>>COc1ccnc(OCc2ccccc2)c1C#N,,Cc1ccccc1,,,,test
US20040082590A1,CC(C)(C)OC(=O)N1CCN(c2ccccc2O)CC1.OCCN1CCOCC1>>CC(C)(C)OC(=O)N1CCN(c2ccccc2OCCN2CCOCC2)CC1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160039811A1,COc1c(Br)cn(C(C(C)C)C2CC2)c(=O)c1C#N.NN>>CC(C)C(C1CC1)n1cc(Br)c2[nH]nc(N)c2c1=O,,CCO,,O,,test
US20130029995A1,Nc1nccc2ccccc12.O=C(Cl)Oc1ccccc1>>O=C(Nc1nccc2ccccc12)Oc1ccccc1,,CC#N,O,c1ccncc1,,test
US20090093530A1,C[C@@H](C(N)=O)c1ccc([N+](=O)[O-])cc1>>C[C@@H](C(N)=O)c1ccc(N)cc1,[Pd],C1CCOC1,CO,O=C[O-].[NH4+],,test
US20120053147A1,CSCC(=O)Cl.Cc1c(Cl)cccc1CNc1nc(N2CCOCC2)sc1C(N)=O>>CSCc1nc(=O)c2sc(N3CCOCC3)nc2n1Cc1cccc(Cl)c1C,,COCCOC,,,,test
US20110144334A1,CI.Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(=O)Nc1cccc(Br)n1>>Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(=O)N(C)c1cccc(Br)n1,,CN(C)C=O,,[H][H],[H-].[Na+],test
US05563141,O=C(COc1ccc(C(=O)CBr)cc1)NCc1ccccc1.c1cc(N2CCNCC2)ccn1>>O=C(COc1ccc(C(=O)CN2CCN(c3ccncc3)CC2)cc1)NCc1ccccc1,,CC#N,,CCOCC,,test
US20100152160A1,CC(C)(C)OC(=O)N1CC(C(=O)N2CCC(C#N)(Cc3ccc(F)cc3)CC2)Oc2cc(Br)c(Cl)cc21.c1cc[nH]c1>>N#CC1(Cc2ccc(F)cc2)CCN(C(=O)C2CNc3cc(Cl)c(-n4cccc4)cc3O2)CC1,I[Cu]I,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04752648,ClP(Cl)(Cl)(Cl)Cl.PC1CCCCC1>>ClP(Cl)C1CCCCC1,,Cc1ccccc1,,,,test
US20020119995A1,CCOC(=O)C(C(=O)OCC)=C1NC(C)=C(S(N)(=O)=O)S1.Nc1ccc(-c2ccccc2)cc1>>CCOC(=O)C(C(=O)Nc1ccc(-c2ccccc2)cc1)=C1NC(C)=C(S(N)(=O)=O)S1,,Cc1ccccc1C,,,,test
US20090012010A1,CC(C)(C#N)c1cccc(C(=O)O)c1.OO>>CC(C)(C(N)=O)c1cccc(C(=O)O)c1,,CCO,,O,[Li]O,test
US20150322043A1,Cc1n[nH]c(C)c1N.O=C(O)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1>>Cc1n[nH]c(C)c1NC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(N(C)C)=[N+]1N=[N+]([O-])c2ncccc21.F[P-](F)(F)(F)(F)F,test
US20090029994A1,CCNc1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(N2CCOCC2)cn1.CCOC(=O)CCCCCC(=O)Cl>>CCOC(=O)CCCCCC(=O)N(CC)c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(N2CCOCC2)cn1,,CCOC(C)=O,ClCCl,CCN(CC)CC,Cl,test
US20140309210A1,C[Si](C)(C)CCOCn1nc(C(=O)O)c2ccc(Br)cc21.Nc1cn[nH]c1>>C[Si](C)(C)CCOCn1nc(C(=O)Nc2cn[nH]c2)c2ccc(Br)cc21,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130252944A1,C=C[Mg]Br.COc1ccc(Cn2cc(I)c(C=O)n2)cc1>>C=CC(O)c1nn(Cc2ccc(OC)cc2)cc1I,,C1CCOC1,,[Cl-].[NH4+],,test
US06136823,CN.Nc1nc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(F)c32)c(F)cc1F>>CNc1c(F)cc2c(=O)c(C(=O)O)cn(-c3nc(N)c(F)cc3F)c2c1F,,c1ccncc1,,,,test
US20150315198A1,COc1ccc(Cl)c(CN)c1F.COc1ncccc1Cc1ccc(Cn2cc3c(Cl)ncnc3n2)cc1>>COc1ccc(Cl)c(CNc2ncnc3nn(Cc4ccc(Cc5cccnc5OC)cc4)cc23)c1F,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US05286723,CCOC(=O)CNC(=O)C1(NC(=O)OC(C)(C)C)CC1>>CCOC(=O)CNC(=O)C1(N)CC1,,O=C(O)C(F)(F)F,,COc1ccccc1,,test
US20130116243A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)NC(=S)CO4)cc2)CCC1.NNC(=O)c1cccnc1>>NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)-n3c(nnc3-c3cccnc3)CO4)cc2)CCC1,,Cc1ccc(C)cc1,,,,test
US20080146623A1,C=Cc1ccc(C(=O)O)cc1.Sc1ccccc1>>CCc1cc(-c2cccs2)ccc1C(=O)O,,c1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20090298823A1,C1CCNC1.Clc1nc(Cl)c2cc[nH]c2n1>>Clc1nc(N2CCCC2)c2cc[nH]c2n1,,C1COCCO1,CCOC(C)=O,CCN(CC)CC,O,test
US20070010670A1,BrCCBr.O=C(Nc1cc(S(=O)(=O)N2CCCC2)ccc1O)c1cc(Cl)c(OCc2ccccc2)c(Cl)c1>>O=C(c1cc(Cl)c(OCc2ccccc2)c(Cl)c1)N1CCOc2ccc(S(=O)(=O)N3CCCC3)cc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060135526A1,CCOC(=O)CC(=O)c1ccccc1.Cc1cc(N)[nH]n1>>Cc1cc2[nH]c(-c3ccccc3)cc(=O)n2n1,,CC(=O)O,,,,test
US20150259346A1,CCOC(=O)C(C)Br.FC(F)C1CCNc2ccccc21>>CCOC(=O)C(C)N1CCC(C(F)F)c2ccccc21,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20040077638A1,CCN(C(C)C)C(C)C.CCN=C=NCCCN(C)C.COC(=O)CC1c2ccccc2C(=O)N(C)c2cc(C(=O)O)ccc21.NCc1nc2ccccc2[nH]1>>COC(=O)CC1c2ccccc2C(=O)N(C)c2cc(C(=O)NCCCCCNc3nc4ccccc4[nH]3)ccc21,,CN(C)C=O,ClCCl,O=C(O)C(F)(F)F,,test
US06143773,CCOC=O.CSc1sc(-c2ccccn2)c2c1C(=O)CC(C)(C)C2>>CSc1sc(-c2ccccn2)c2c1C(=O)C(=CO)C(C)(C)C2,,C1CCOC1,,CO,[H-].[Na+],test
US20140206663A1,CC1C(=O)NN=C2COc3cc(C4CC4)c(OC4CN(C(=O)OC(C)(C)C)C4)cc3N21.O=C(O)C(F)(F)F>>CC1C(=O)NN=C2COc3cc(C4CC4)c(OC4CNC4)cc3N21.O=C(O)C(F)(F)F,,ClCCl,,,,test
US07183290B2,CC(C)(C)OC(=O)NC1CCNCC1.N#Cc1ccc(F)cc1F>>CC(C)(C)OC(=O)NC1CCN(c2ccc(C#N)c(F)c2)CC1,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20020165241A1,O=C(OCc1ccccc1)N1CCC(CNc2c(Cl)c(Cl)nc(Cl)c2Cl)C(O)C1>>OC1CNCCC1CNc1ccncc1,[Pd],CCO,,O=C([O-])[O-].[K+].[K+],,test
US06974869B2,N[C@@H]1CCCC[C@@H]1CN1CC(=O)O[C@@H](Cc2ccccc2)C1.O=C1OCCN(C(=O)OCc2ccccc2)C1C1CCCCC1>>NC1C(=O)OCCN1C1CCCCC1,[Pd],CO,,[H][H],,test
US20070015744A1,CC(C)(C)OC(=O)N1CCN(c2cccc3c2CC(=O)N3Cc2cccc(F)c2)CC1>>O=C1Cc2c(N3CCNCC3)cccc2N1Cc1cccc(F)c1,,CCO,,CCOCC,Cl,test
US20130072493A1,Cc1ccc(F)c(S(=O)(=O)Cl)c1.Nc1ccc(-c2cnc3c(N)n[nH]c3n2)cc1>>Cc1ccc(F)c(S(=O)(=O)Nc2ccc(-c3cnc4c(N)n[nH]c4n3)cc2)c1,,ClCCl,c1ccncc1,Cl,,test
US20130338138A1,O=P(Cl)(Cl)Cl.Oc1ncc2ccc(Cl)cc2n1>>Clc1ccc2cnc(Cl)nc2c1,,CCOC(C)=O,O,,,test
US20140213586A1,COc1cccc(NC(C(=O)c2c[nH]c3ccccc23)c2ccccc2)c1.O=C(Cl)CCl>>COc1cccc(N(C(=O)CCl)C(C(=O)c2c[nH]c3ccccc23)c2ccccc2)c1,,ClCCl,,CCN(CC)CC,,test
US20130085142A1,COC(=O)[C@@H]1C[C@@H](O)CN1CC#N>>O=C1NCCN2C[C@H](O)C[C@@H]12,[Ni],CO,,,,test
US04881965,CN(C)S(=O)(=O)c1cccc(Cl)n1.NN>>CN(C)S(=O)(=O)c1cccc(NN)n1,,CCCCO,,O,,test
US20120040984A1,CC(C)(C)OC(=O)c1ccc(O)cc1.COC(=O)[C@@H]1CC[C@H](O)CC1>>COC(=O)[C@@H]1CC[C@@H](Oc2ccc(C(=O)OC(C)(C)C)cc2)CC1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030199550A1,CN(C[C@@H]1CC[C@@H](CCOS(C)(=O)=O)CC1)S(=O)(=O)c1ccc(C(F)(F)F)cc1.c1c[nH]cn1>>CN(C[C@@H]1CC[C@@H](CCn2ccnc2)CC1)S(=O)(=O)c1ccc(C(F)(F)F)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20150080549A1,C[C@H](NC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](CC(=O)OCc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O>>C[C@H](NC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](CC(=O)O)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O,[Pd],CO,,[H][H],,test
US20120264923A1,CC(=CCCCOS(=O)(=O)c1ccc(C)cc1)CCCC(C)CCCC(C)CCCC(C)C.OCC(CO)(CO)COCC(CO)(CO)CO>>CC(=CCCCOCC(CO)(CO)COCC(CO)(CO)CO)CCCC(C)CCCC(C)CCCC(C)C,,CN(C)C=O,,O,[H-].[Na+],test
US20150344466A1,CCOC(=O)c1cc(CCCc2ccc3ccccc3c2)on1>>O=C(O)c1cc(CCCc2ccc3ccccc3c2)on1,,CCO,,O,[K+].[OH-],test
US20160029630A1,CC(C)C(O)(Cn1cncn1)c1ccc(Br)cc1.Oc1cccc(Cl)c1>>CC(C)C(O)(Cn1cncn1)c1ccc(Oc2cccc(Cl)c2)cc1,[Cu]I,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060041003A1,CCC1(CC(C)=O)CCc2cc(OC)ccc2C1=O>>CCC12CCc3cc(OC)ccc3C1=CC(=O)C2,,CCO,CCOC(C)=O,[K+].[OH-],,test
US05726192,CNCC(=O)OCc1ccccc1.O=C1CCC(=O)O1>>CN(CC(=O)OCc1ccccc1)C(=O)CCC(=O)O,,Cc1ccccc1,,,,test
US20040063680A1,CC(C)S(=O)(=O)NCC(C)(F)c1ccc(I)cc1.OB(O)Oc1ccccc1>>CC(C)S(=O)(=O)NCC(C)(F)c1ccc(-c2ccccc2)cc1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US04522828,CCOCC.N#CC1(c2ccccc2)CCC1>>O=CC1(c2ccccc2)CCC1,,CCCCCC,,Cl,,test
US20070032478A1,CCn1cc(Cl)c(C(=O)O)n1.Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3)c1>>CCn1cc(Cl)c(C(=O)Nc2cccc(C(=O)c3ccc4c(c3)NC(=O)C4)c2)n1,,C1CCOC1,,O=S(Cl)Cl,,test
US05350748,CC(C)Oc1c(C(=O)O)oc2ccc(Cl)cc12.Nc1ccccc1>>CC(C)Oc1c(C(=O)Nc2ccccc2)oc2ccc(Cl)cc12,,C1CCOC1,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20090098086A1,C1CC2COCC1N2.Oc1cccc(-c2nc(Br)c3cnn(-c4ccccc4)c3n2)c1>>Oc1cccc(-c2nc(N3C4CCC3COC4)c3cnn(-c4ccccc4)c3n2)c1,,CCO,,CCN(CC)CC,Cl,test
US20130172330A1,CCOC(=O)c1nccc2c1[nH]c1ccccc12>>O=Cc1nccc2c1[nH]c1ccccc12,,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US04629784,C=C(NC(=O)OC(C)(C)C)C(=O)OCc1ccc([N+](=O)[O-])cc1.CC(C)C=[N+]=[N-]>>CC(C)C1CC(NC(=O)OC(C)(C)C)(C(=O)OCc2ccc([N+](=O)[O-])cc2)NN1,,ClCCl,,,,test
US20070099925A1,CC(C)(CN)CO.CC(C)Oc1nccn2c(-c3ccnc(S(C)(=O)=O)n3)c(-c3ccc(F)cc3)nc12>>CC(C)Oc1nccn2c(-c3ccnc(NCC(C)(C)CO)n3)c(-c3ccc(F)cc3)nc12,,CC#N,,,,test
US05175162,Cc1cc2c(s1)SCC(CC(=O)O)C2=O.NNc1ccc(Cl)cc1>>Cc1cc2c(s1)SCC1CC(=O)N(c3ccc(Cl)cc3)N=C21,,CCO,,,,test
US20070208018A1,COC(=O)c1cc(-n2cnc(Br)c2)c(C(F)(F)F)cc1[N+](=O)[O-]>>COC(=O)c1cc(-n2cnc(Br)c2)c(C(F)(F)F)cc1N,[Pd],CO,,,,test
US20140275026A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.COc1nc(Br)cc2c(-c3cc([N+](=O)[O-])ccc3Oc3ccc(F)cc3F)cn(C)c12>>COc1nc(C2=CCN(C(=O)OC(C)(C)C)CC2)cc2c(-c3cc([N+](=O)[O-])ccc3Oc3ccc(F)cc3F)cn(C)c12,,C1CCOC1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20160130254A1,CC(C)(C)OC(=O)NC1CC=C(C=O)C1.COC(C)(C)CN.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>COC(C)(C)Cn1cncc1C1=CCC(NC(=O)OC(C)(C)C)C1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US06610692B1,CS(=O)(=O)Cl.OCCCCC1CC1>>CS(=O)(=O)OCCCCC1CC1,,ClCCl,,CCN(CC)CC,,test
US20130237571A1,CC(=O)c1ccc(OCc2ccccc2)cc1.COC(=O)OC>>COC(=O)CC(=O)c1ccc(OCc2ccccc2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US05491144,COC(=O)c1cc(NC2CCCCC2)c(NC2CCCCC2)cc1C(=O)OC.N>>O=C1NC(=O)c2cc(NC3CCCCC3)c(NC3CCCCC3)cc21,,OCCO,,[Cl-].[Na+],,test
US04192888,COC(=O)CCc1ccccc1Cl>>O=C(O)CCc1ccccc1Cl,,[Na+],[OH-],,,test
US20150038510A1,CC(C)(C)OC(=O)Nc1cccc(Cl)c1Br>>Nc1cccc(Cl)c1Br,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100152163A1,CC(=CBr)c1cccnc1.Cc1ccc2[nH]c3c(c2c1)CCN(C)CC3>>C/C(=C\n1c2c(c3cc(C)ccc31)CCN(C)CC2)c1cccnc1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20070106095A1,CCC(O)(CC)c1cc2cc(OCc3ccccc3)ccc2o1.Cc1ccccc1O>>CCC(CC)(c1ccc(O)c(C)c1)c1cc2cc(OCc3ccccc3)ccc2o1,,ClCCl,,CCOCC,FB(F)F,test
US20160046618A1,COC(=O)[C@]12C[C@H]1[C@@](CF)(c1cc(N)ccc1F)N=C(N)S2>>NC1=N[C@](CF)(c2cc(N)ccc2F)[C@@H]2C[C@]2(CO)S1,,C1CCOC1,,CO,[BH4-].[Li+],test
US20130079313A1,BrCC1CC1.COC(=O)Cc1ccc(O)c([N+](=O)[O-])c1>>COC(=O)Cc1ccc(OCC2CC2)c([N+](=O)[O-])c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040023961A1,O=[N+]([O-])c1ccc(OCCN2CCOCC2)c2ccccc12>>Nc1ccc(OCCN2CCOCC2)c2ccccc12,[Pd],CO,,,,test
US06124283,CC(=O)Cl.CCCCCN1CCN(c2cccc3c2C[C@H](N)CC3)CC1>>CCCCCN1CCN(c2cccc3c2C[C@H](NC(C)=O)CC3)CC1,,ClCCl,,CCN(CC)CC,,test
US20100048564A1,CC(C)(C)OC(=O)NCc1cc(Cl)ccc1[N+](=O)[O-].Oc1ccc2c(c1)OCO2>>CC(C)(C)OC(=O)NCc1cc(Oc2ccc3c(c2)OCO3)ccc1[N+](=O)[O-],,CN1CCCC1=O,,[H-].[Na+],,test
US04761413,Fc1ccccc1Br.c1coc(C2OCCO2)c1>>C1=CC2(C3OCCO3)OC1c1ccccc12,,C1CCOC1,,[Mg],[Cl-].[NH4+],test
US20100179126A1,C1COCCN1.Cc1nc(F)ccc1[N+](=O)[O-]>>Cc1nc(N2CCOCC2)ccc1[N+](=O)[O-],,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150210682A1,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OC)cc1CC2CC(F)(F)F>>COc1cc2c(cc1OC)-c1cc(=O)c(C(=O)O)cn1C(CC(F)(F)F)C2,,CO,O,Cl,[Li]O,test
US20150018309A1,Cc1ccc(S(=O)(=O)CF)cc1.O=C1CCC(=O)N1Br>>O=S(=O)(CF)c1ccc(CBr)cc1,,CC#N,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20100080772A1,C=Cc1cccnc1C(=O)OC>>CCc1cccnc1C(=O)OC,[Pd],CCO,,,,test
US20120041009A1,NC(=NO)c1cc(C(F)(F)C(F)(F)C(F)(F)F)ncn1.O=C(n1ccnc1)n1ccnc1>>O=c1nc(-c2cc(C(F)(F)C(F)(F)C(F)(F)F)ncn2)[nH]o1,,C1CCOC1,O,C1CCC2=NCCCN2CC1,Cl,test
US20130023541A1,CC1(C)C(C(=O)O)C1(C)C.CCN(Cc1ccc(CN2CCN(c3ncccc3CO)CC2)cc1)Cc1c(F)cccc1Cl>>CCN(Cc1ccc(CN2CCN(c3ncccc3COC(=O)C3C(C)(C)C3(C)C)CC2)cc1)Cc1c(F)cccc1Cl,,CO,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20150038488A1,CC[Mg]Br.COc1ccc([C@@H](C)N2C[C@H](C(=O)N(C)OC)CC2=O)cc1>>CCC(=O)[C@@H]1CC(=O)N([C@H](C)c2ccc(OC)cc2)C1,,C1CCOC1,C1CCOC1,,,test
US20140357713A1,CC(C)(Br)C(=O)Br.CCCCCCCCCCCC(C)O>>CCCCCCCCCCCC(C)OC(=O)C(C)Br,,Cc1ccccc1,,CCN(CC)CC,,test
US20160052884A1,COc1cn(C(C[C@@H]2CC[C@H](OC)CC2)C(=O)OC(C)(C)C)c(=O)cc1-c1cc(Cl)ccc1C#N>>COc1cn(C(C[C@@H]2CC[C@H](OC)CC2)C(=O)O)c(=O)cc1-c1cc(Cl)ccc1C#N,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070066624A1,CI.COC(=O)c1ccc2c(c1)CNC2=O>>COC(=O)c1ccc2c(c1)CN(C)C2=O,,CN(C)C=O,,[H-].[Na+],,test
US20080207608A1,CN1CCNCC1.NCCBr>>CN1CCN(CCN)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20030176481A1,CSc1ccc(N)cc1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1ccc(N)cc1,,ClCCl,,ClC(Cl)Cl,,test
US04663341,CCOC(=O)Cl.O=C(Nc1ccc(Cl)cc1)N1CCC(c2ccc(Cl)cc2)=N1>>CCOC(=O)C1CN(C(=O)Nc2ccc(Cl)cc2)N=C1c1ccc(Cl)cc1,,C1CCOC1,CCCCCC,CC(C)NC(C)C,[Li]CCCC,test
US05690858,C=CCCCCCCCCCOS(=O)(=O)c1ccc(C)cc1.CCOC(=O)c1cc(O)ccc1-c1ccccc1>>C=CCCCCCCCCCOc1ccc(-c2ccccc2)c(C(=O)OCC)c1,,O,,CN(C)C=O,[H-].[Na+],test
US20100286115A1,COC(=O)/C=C(/NN)C(=O)OC>>COC(=O)c1cc(O)n[nH]1,,Cc1ccccc1C,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040092556A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccc(CCNCc2ccccn2)cc1>>COC(=O)c1ccc(CCN(Cc2ccccn2)C(=O)OC(C)(C)C)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20050075378A1,CCI.COC(=O)CCc1ccc(OCCc2nc(-c3ccc(-c4ccccc4)cc3)oc2C)cc1CNC(=O)OC(C)C>>CCN(Cc1cc(OCCc2nc(-c3ccc(-c4ccccc4)cc3)oc2C)ccc1CCC(=O)O)C(=O)OC(C)C,,CCOC(C)=O,CN(C)C=O,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20100069381A1,CCOC(=O)CCc1cccc(C(F)(F)F)c1.NN>>NNC(=O)CCc1cccc(C(F)(F)F)c1,,CCO,,O,,test
US20120329785A1,COc1cc(C(=O)N2CCC(N3CCN(C)CC3)CC2)ccc1N.COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1>>COc1ccc2nc(Nc3ccc(C(=O)N4CCC(N5CCN(C)CC5)CC4)cc3OC)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US20150133428A1,NC(=O)c1c(-c2ccc(F)c(Cl)c2)nn2c1CNCC2.O=C(O)C1(C(F)F)CC(F)(F)C1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>NC(=O)c1c(-c2ccc(F)c(Cl)c2)nn2c1CN(C(=O)NC1(C(F)F)CC(F)(F)C1)CC2,,Cc1ccccc1,,CN(C)C=O,,test
US05080905,CI.Nc1cccc2c(=O)[nH]c3ccccc3c(=O)c12>>Cn1c(=O)c2cccc(N)c2c(=O)c2ccccc21,,CN(C)C=O,,O,[H-].[Na+],test
US20070111926A1,CC(C)(C)OC(=O)NCc1cccc(CO)c1>>NCc1cccc(CO)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100240708A1,CCOC(=O)[C@@H]1CCC[C@@H]1NS(=O)(=O)c1ccc(Cl)cc1>>O=S(=O)(N[C@@H]1CCC[C@@H]1CO)c1ccc(Cl)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060252812A1,Nc1ccc(F)cc1N.O=C(O)CN1C(=O)C2(COc3cc4c(cc32)OCO4)c2ccccc21>>O=C1N(Cc2nc3cc(F)ccc3[nH]2)c2ccccc2C12COc1cc3c(cc12)OCO3,,Cc1ccccc1,O,,,test
US20150203483A1,CNC(=O)N1N=C(c2ccc(NC(=O)COCCCl)cc2)c2cc(OC)ccc2C[C@@H]1C>>CNC(=O)N1N=C(c2ccc(N3CCOCC3=O)cc2)c2cc(OC)ccc2C[C@@H]1C,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US20090005353A1,CC(C)(C)N1C(=O)C(Cl)=C(c2ccccc2)S1(=O)=O.COC(=O)CN>>COC(=O)CNC1=C(c2ccccc2)S(=O)(=O)N(C(C)(C)C)C1=O,,CC#N,CN(C)C=O,Cl,,test
US20040186301A1,CC(C)(C)OC(=O)CC(CC(=O)OC(C)(C)C)(C(=O)O)C(=O)O>>CC(C)(C)OC(=O)CC(CC(=O)OC(C)(C)C)C(=O)O,,CCOC(C)=O,,O=CO,,test
US20080167287A1,CC(C)(C)OC(=O)CBr.Nc1ncc(Br)cn1.OB(O)c1ccn[nH]1>>CC(C)(C)OC(=O)Cn1ccc(-c2cnc(N)nc2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030092749A1,CN(C)C=O.ClCCl.O=C(O)c1ccc(F)c([N+](=O)[O-])c1>>CON(C)C(=O)c1ccc(F)c([N+](=O)[O-])c1,,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20110301167A1,CC(C)(C)OC(=O)NN.O=C1CCCOC1>>CC(C)(C)OC(=O)NNC1CCCOC1,,ClCCCl,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130225633A1,FCBr.O=C(O)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1cccc(N3CC[C@@H](F)C3)c1)C2>>O=C(OCF)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1cccc(N3CC[C@@H](F)C3)c1)C2,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],,test
US20100216802A1,CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(CC[C@H](NC(=O)OC(C)(C)C)C(=O)OC5CCCC5)C4)cc3OC)nc2N1C1CCCC1>>CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(CC[C@H](N)C(=O)OC5CCCC5)C4)cc3OC)nc2N1C1CCCC1,,C1COCCO1,Cl,,,test
US20090156600A1,COC(=O)C(Cl)C(C)=O.Sc1ccc(Cl)cc1>>COC(=O)C(Sc1ccc(Cl)cc1)C(C)=O,,ClCCl,,CCN(CC)CC,,test
US20160002175A1,Cc1cccc(-c2cc(Cl)nc(N)n2)c1C.NCCc1cccnc1>>Cc1cccc(-c2cc(NCCc3cccnc3)nc(N)n2)c1C,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20100311966A1,CCOC(=O)c1sc(Br)nc1C.Oc1cc(Cl)ccn1>>CCOC(=O)c1sc(-n2ccc(Cl)cc2=O)nc1C,[Cu]I,CCOC(C)=O,CN(C)C=O,CN[C@@H]1CCCC[C@H]1NC,O=C([O-])[O-].[K+].[K+],test
US05403842,Cc1c(-c2ccccc2)oc2c(CO)cccc2c1=O.O=S(Cl)Cl>>Cc1c(-c2ccccc2)oc2c(CCl)cccc2c1=O,,ClC(Cl)Cl,O,CCN(CC)CC,,test
US04005208,CCN1CCCC(NC2c3ccccc3Oc3ccccc32)C1.O=C(O)[C@@H](O)[C@H](O)C(=O)O>>CCN1CCCC(NC2c3ccccc3Oc3ccccc32)C1.O=C([O-])C(O)C(O)C(=O)[O-],,C1CCOC1,,CCOCC,,test
US20050222139A1,CC(=O)Cl.Nc1cnc2ccccc2c1>>CC(=O)Nc1cnc2ccccc2c1,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,Cl,test
US20110166163A1,COC(=O)CCCCCNc1ncnc2oc(-c3ccccc3)c(B3OC(C)(C)C(C)(C)O3)c12.Cc1ccc(Br)nc1>>COC(=O)CCCCCNc1ncnc2oc(-c3ccccc3)c(-c3ccc(C)cn3)c12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CS(C)=O,,CO,O=C([O-])[O-].[K+].[K+],test
US20070179185A1,C=O.Clc1cccc(C2CCNCC2)c1Cl>>CN1CCC(c2cccc(Cl)c2Cl)CC1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04374133,CC1CCC2=CC=NC=Cc3ccccc3OC2C1.O=C(O)/C=C\C(=O)O>>CC1CCC2=CC=NC=Cc3ccccc3OC2C1.O=C(O)/C=C\C(=O)O,,CCO,,,,test
US04685961,C=O.COc1cc(C)nc(N)n1.c1nc[nH]n1>>COc1cc(C)nc(NCn2cncn2)n1,,CO,,CC(=O)O,,test
US20100216986A1,C=Cc1ccc(-c2ccc(-c3ccc(OCCC)c(F)c3F)cc2)[se]1>>CCCOc1ccc(-c2ccc(-c3ccc(CC)[se]3)cc2)c(F)c1F,[Pd],CCOC(C)=O,Cc1ccccc1,,,test
US20100022522A1,O=C(O)C(F)(F)F.c1nc(-c2cnn(C(CC3CC3)C3CCCC3)c2)c2cc[nH]c2n1>>CCCC(C1CCCC1)n1cc(-c2ncnc3[nH]ccc23)cn1.O=C(O)C(F)(F)F,[Pd],CO,,[H][H],,test
US20070106095A1,CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc2cc(O)ccc2o1.CS(=O)(=O)Cl>>CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc2cc(OS(C)(=O)=O)ccc2o1,,ClCCl,,CCN(CC)CC,,test
US20120208817A1,NC(N)=O.O=C(Cc1ccccc1)c1ccccc1.O=Cc1ccc(O)c(C(=O)O)c1>>O=C1NC(c2ccccc2)=C(c2ccccc2)C(c2ccc(O)c(C(=O)O)c2)N1,,CCO,,Cl,,test
US04622318,C=CSCC1=C(C(=O)O)N2C(=O)C(NC(=O)C(=NOC)c3csc(NC(=O)C(F)(F)F)n3)[C@H]2SC1.Cl>>C=CSCC1=C(C(=O)O)N2C(=O)C(NC(=O)C(=NOC)c3csc(N)n3)[C@H]2SC1.Cl,,O,,CC(=O)[O-].[Na+],,test
US20070219196A1,CCCc1nc2c(N)nc3ccccc3c2n1CCCCC(=O)N1CCOCC1>>CCCc1nc2c(N)nc3c(c2n1CCCCC(=O)N1CCOCC1)CCCC3,O=[Pt]=O,,,O=C(O)C(F)(F)F,,test
US20160039821A1,CCS(=O)(=O)c1ccc(F)c(Br)c1.C[C@@H](N)c1ccccc1>>CCS(=O)(=O)c1ccc(N[C@H](C)c2ccccc2)c(Br)c1,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US05037822,O=C(O)CCCCN(C1CCNCC1)S(=O)(=O)c1ccccc1>>O=C1CCCCN1S(=O)(=O)c1ccc(N2CCCCC2)cc1,,CC(=O)OC(C)=O,,CC(=O)[O-].[Na+],,test
US04049717,CC(=O)NC1CCC(=O)c2ccccc21>>NC1CCC(=O)c2ccccc21,,O,,Cl,,test
US20160159808A1,Cc1c[nH]nn1.Cc1cn2ncc(C(=O)OC(C)(C)C)c2nc1Cl>>Cc1cn(-c2nc3c(C(=O)OC(C)(C)C)cnn3cc2C)nn1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20030236298A1,COc1cc(C=CC(=O)c2cc(OC)c(OC)c(OC)c2)cc(Br)c1OC.OB(O)c1cccs1>>COc1cc(C(=O)C=Cc2cc(OC)c(OC)c(-c3cccs3)c2)cc(OC)c1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US20050038040A1,COc1ccc(N)c(C(F)(F)F)n1.[I-]>>COc1ccc(I)c(C(F)(F)F)n1,,O,O=S(=O)(O)O,O=N[O-].[Na+],,test
US20100317645A1,CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3ccc(-c4noc(CO)n4)cc32)cc1.O=C1CCC(=O)N1I>>CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3c(I)cc(-c4noc(CO)n4)cc32)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060009456A1,CC(=O)Cl.COc1cc(N2CCN3C(CCCC3c3ccc(OCCCN)c(C)c3C)C2)ccc1Cl>>COc1cc(N2CCN3[C@@H](CCC[C@@H]3c3ccc(OCCCNC(C)=O)c(C)c3C)C2)ccc1Cl,,ClCCl,,CCN(CC)CC,,test
US03934022,Clc1cccc(C(Cl)(c2ccccc2)c2ccccc2)c1.c1c[nH]cn1>>Clc1cccc(C(c2ccccc2)(c2ccccc2)n2ccnc2)c1,,CC#N,CN(C)C=O,O,,test
US05912246,C1CNCCN1.NC(=O)c1ccc(F)cc1>>NC(=O)c1ccc(N2CCNCC2)cc1,,O,,,,test
US20160102064A1,O[C@@H](CCl)CNc1ccc(N2CCOCC2)c(F)c1>>Fc1cc(NC[C@@H]2CO2)ccc1N1CCOCC1,,ClCCl,,O,[Na+].[OH-],test
US20130072467A1,CCN(CC)CC#CCNC1=NC(=O)SC1.O=CC1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1>>CCN(CC)CC#CCNC1=NC(=O)S/C1=C\C1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1,,CC(C)O,,C1CC[NH2+]CC1.CC(=O)[O-],,test
US06777406B2,C1CCCCC1.CC(C)(C)OC(=O)N1CCCOc2ccccc21.CCOCC.CN(C)C=O.CN(C)CCN(C)C>>O=C1[C@@H]2CN(Cc3ccccc3)C[C@@H]2c2cccc3c2N1CCCO3,,C1CCCCC1,,[Li]C(C)CC,,test
US20090281324A1,CC(C)(C)O.NC(=O)CBr.O=C(Cl)C(=O)Cl>>CC(C)(C)OC(=O)NC(=O)CBr,,ClCCCl,ClCCl,CCCCCCC,,test
US20150148340A1,Cn1c(=O)n(CC(F)(F)F)c2cc([N+](=O)[O-])ccc21>>Cn1c(=O)n(CC(F)(F)F)c2cc(N)ccc21,[Pd],CO,,O=C[O-].[NH4+],,test
US05106871,CC(C)=CCc1c(OCc2ccccc2)ccc(C(=O)C=Cc2ccc(OCc3ccccc3)cc2)c1O>>CC(C)CCc1c(O)ccc(C(=O)CCc2ccc(O)cc2)c1O,[Pd],CCOC(C)=O,,[H][H],,test
US20070032489A1,CCc1cc(-c2ccc(S(=O)(=O)Cl)s2)c(C)[nH]c1=O.c1ccc(N2CCNCC2)cc1>>CCc1cc(-c2ccc(S(=O)(=O)N3CCN(c4ccccc4)CC3)s2)c(C)[nH]c1=O,,ClCCl,,CCOC(C)=O,,test
US20100197675A1,O=C(NCC12CC3CC(CC(C3)C1)C2)[C@@H](O)c1ccccc1>>O[C@H](CNCC12CC3CC(CC(C3)C1)C2)c1ccccc1,,C1CCOC1,,CSC,,test
US20130172595A1,CC(C)C[Mg]Br.CCO[Si](Cl)(OCC)C1CCCC1>>CCO[Si](CC(C)C)(OCC)C1CCCC1,,CCOCC,,[Cl-].[NH4+],,test
US05216148,CCOC(=O)c1ccc(C(=O)Nc2ccc3c(c2)C(C)(C)CCC(=O)N3C)cc1>>CN1C(=O)CCC(C)(C)c2cc(NC(=O)c3ccc(C(=O)O)cc3)ccc21,,CCO,O,[Na+].[OH-],,test
US20070099915A1,COC(=O)c1ncc2c(ccn2Cc2ccc(F)cc2)c1/C=C\CN(OC(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>COC(=O)c1ncc2c(ccn2Cc2ccc(F)cc2)c1/C=C\CNO,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060084680A1,CC(=O)C(C)Br.CCOC(=O)C[C@@H]1CCc2cc(OCCCOc3ccc(C(N)=S)cn3)ccc21>>CCOC(=O)C[C@@H]1CCc2cc(OCCCOc3ccc(-c4nc(C)c(C)s4)cn3)ccc21,,CCO,,,,test
US20080021028A1,CC(C)OC(=O)[C@H](CCCc1ccc(OC(F)(F)F)cc1)[C@H](O)C(=O)OC(C)C>>O=C(O)[C@H](CCCc1ccc(OC(F)(F)F)cc1)[C@H](O)C(=O)O,,C1CCOC1,O,Cl,[K+].[OH-],test
US20020120141A1,O=[N+]([O-])c1cnc2ccccc2c1NCCO>>Nc1cnc2ccccc2c1NCCO,[Pt],CCO,,,,test
US20110071175A1,COC(=O)Cn1c(C)c(Cc2cccnc2S(=O)(=O)N(C)c2ccccc2)c2cc(F)ccc21>>Cc1c(Cc2cccnc2S(=O)(=O)N(C)c2ccccc2)c2cc(F)ccc2n1CC(=O)O,,Cl,,CO,[Na+].[OH-],test
US20100280005A1,BrCCBr.COC(=O)CC(O)CNS(=O)(=O)c1ccccc1[N+](=O)[O-]>>COC(=O)CC(O)CN(CCBr)S(=O)(=O)c1ccccc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060079554A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.NCC1CC1>>CC(C)(C)OC(=O)N1CCC(NCC2CC2)CC1,,ClCCCl,,CC(=O)O,[Na+].[OH-],test
US07074801B1,CCOC(=O)c1ccc(Nc2ccccc2[N+](=O)[O-])cc1F>>CCOC(=O)c1ccc(Nc2ccccc2N)cc1F,[Fe],O,,CO,[Cl-].[NH4+],test
US06174458B1,CCCCCC1CCC(O)(c2cc(F)cc(F)c2)CC1>>CCCCCC1CC=C(c2cc(F)cc(F)c2)CC1,,Cc1ccccc1,,,,test
US05539112,CC(C)(C)C(=O)Nc1ccc(-c2cc(=O)c3c(NC(=O)C(C)(C)C)c(F)c(O)c(F)c3o2)cc1F.CI>>COc1c(F)c(NC(=O)C(C)(C)C)c2c(=O)cc(-c3ccc(NC(=O)C(C)(C)C)c(F)c3)oc2c1F,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110269737A1,COC(=O)c1cc(C(C)(C)C)cc([N+](=O)[O-])c1OC>>COC(=O)c1cc(C(C)(C)C)cc(N)c1OC,[Pd],CO,,[H][H],,test
US05290477,CCCCC[C@H](COS(=O)(=O)c1ccc(C)cc1)OC1CCCCO1.Oc1cnc(-c2ccc(OCc3ccccc3)cc2)nc1>>CCCCC[C@H](COc1cnc(-c2ccc(OCc3ccccc3)cc2)nc1)OC1CCCCO1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120165339A1,ClC[C@H]1CO1.N#CCc1cccc(F)c1.O>>O=C1OC[C@@H]2C[C@]12c1cccc(F)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20120142705A1,CC(C)CC(C(=O)O)N1C(=O)C(=O)c2cc(Br)ccc21.Nc1ccccn1>>CC(C)CC(C(=O)Nc1ccccn1)N1C(=O)C(=O)c2cc(Br)ccc21,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US04414216,Fc1ccc([C@H]2C[C@H](CI)CO2)cc1.O=c1[nH]c2ccccc2n1C1CCNCC1>>O=c1[nH]c2ccccc2n1C1CCN(C[C@@H]2CO[C@@H](c3ccc(F)cc3)C2)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20140200207A1,CNC(=O)c1ccc([N+](=O)[O-])c(OC)n1>>CNC(=O)c1ccc(N)c(OC)n1,[Pd],CO,,,,test
US05834463,ClCc1ccccn1.O=C1Nc2ccccc2N(C(=O)CN2C(=O)c3ccccc3C2=O)[C@@H]2CCC[C@H]12>>O=C1c2ccccc2C(=O)N1CC(=O)N1c2ccccc2N(Cc2ccccn2)C(=O)[C@H]2CCC[C@H]21,,CN(C)C=O,,O,[H-].[Na+],test
US20100261750A1,N#CC1(c2ccc(OC(F)(F)F)cc2)CCCC1>>NCC1(c2ccc(OC(F)(F)F)cc2)CCCC1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04282031,NN.S=C=Nc1ccc2ccccc2c1>>NNC(=S)Nc1ccc2ccccc2c1,,CCOCC,,,,test
US20040009967A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCCCCC1CCNCC1>>CC(C)(C)OC(=O)N1CCC(CCCCO)CC1,,C1CCOC1,O,Cl,,test
US20160168156A1,C1CNCCNC1.Fc1ccc(F)c([C@H]2CCCN2c2ccn3ncc(-c4nnc(Br)s4)c3n2)c1>>Fc1ccc(F)c([C@H]2CCCN2c2ccn3ncc(-c4nnc(N5CCCNCC5)s4)c3n2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20160222028A1,COC(=O)c1ccc(CN[C@@H](CO)C(C)C)c(Br)c1>>COC(=O)c1ccc2c(c1)OC[C@@H](C(C)C)NC2,[Cu]I,CC(C)O,,O=C([O-])[O-].[K+].[K+],,test
US20080207666A1,CC(=O)NC1CC(C)(COCc2ccccc2)Oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc21>>CC(=O)NC1CC(C)(CO)Oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc21,,ClCCl,,,,test
US20030004169A1,ClCCCl.FC(F)(F)c1cc(C2CCN(Cc3ccccc3)CC2)ccc1Cl>>Cl.FC(F)(F)c1cc(C2CCNCC2)ccc1Cl,,ClCCCl,,CC(Cl)OC(=O)Cl,,test
US04904669,CC(=O)Nc1cnc2cc(Cl)ccc2c1S>>Cc1nc2cnc3cc(Cl)ccc3c2s1,,O,,[Na+].[OH-],,test
US20160024044A1,CN(C[C@H](c1ccc2ccccc2c1)[C@H](O)c1ccccc1)C(=O)OC(C)(C)C.O=C(O)c1ccc(Cl)cc1>>CN(C[C@H](c1ccc2ccccc2c1)[C@@H](OC(=O)c1ccc(Cl)cc1)c1ccccc1)C(=O)OC(C)(C)C,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060009456A1,COc1cc(N2CCN3C(CCCC3c3ccc(OCCCN4C(=O)c5ccccc5C4=O)c(C)c3C)C2)ccc1Cl>>COc1cc(N2CCN3C(CCCC3c3ccc(OCCCN)c(C)c3C)C2)ccc1Cl,,CCO,ClCCl,,,test
US20110144336A1,BrCc1ccccc1.CCOC(=O)C(C)N=Cc1ccccc1>>CCOC(=O)C(C)(N)Cc1ccccc1,,C1CCOC1,COC(C)(C)C,Cl,CC(C)[N-]C(C)C.[Li+],test
US20090298807A1,CC(C)c1nc(C(=O)N2CCOC3(CCN(Cc4csc(CCO[Si](C)(C)C(C)(C)C)c4)CC3)C2)cs1>>CC(C)c1nc(C(=O)N2CCOC3(CCN(Cc4csc(CCO)c4)CC3)C2)cs1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04772600,CC(C)N.O=C(O)Cn1c(-c2ccc(Cl)cc2)nc2cccnc21>>CC(C)NC(=O)Cn1c(-c2ccc(Cl)cc2)nc2cccnc21,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US06169107A,Cl.N=C(N)N.O=C(OCc1ccccc1)c1ccc2c(ccn2Cc2ccccc2)c1>>Cl.N=C(N)NC(=O)c1ccc2c(ccn2Cc2ccccc2)c1,,CO,,C[O-].[Na+],,test
US20100286181A1,Cc1[nH]c(C(=O)N[C@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2N=[N+]=[N-])c(Cl)c1Cl.Cl>>Cc1[nH]c(C(=O)N[C@H]2CCNC[C@H]2N=[N+]=[N-])c(Cl)c1Cl.Cl,,CO,Cl,,,test
US20100105667A1,Cc1ccc(NC(=O)OC(C)(C)C)nc1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)Nc1ccc(CBr)cn1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US05668137,CC(C)COC(=O)Cl.COc1nc(C)cnc1NS(=O)(=O)c1ccccc1I>>COc1nc(C)cnc1N(C(=O)OCC(C)C)S(=O)(=O)c1ccccc1I,,ClCCl,c1ccncc1,CCN(CC)CC,Cl,test
US04157399,CCCN(C)c1c(-c2ccccc2)sc2ccccc12.O=CO>>O=CNc1c(-c2ccccc2)sc2ccccc12,,O,,,,test
US20120118832A1,C=C1CCOC1=O.C=CC(=O)O.CS(C)=O>>C=C1CC(C)OC1=O.C=CC(=O)O,,CS(C)=O,,,,test
US20080103123A1,CC(C)N(Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1)C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)N(Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1)C1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160214971A1,CS(=O)(=O)NC(=O)c1ccc(-c2cnc(F)c(Cl)c2)c(OC2COC2)c1.Cc1ccc(Cl)c(O)c1>>Cc1ccc(Cl)c(Oc2ncc(-c3ccc(C(=O)NS(C)(=O)=O)cc3OC3COC3)cc2Cl)c1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100041663A1,Brc1ccc(I)cn1.CC(C)=O>>CC(C)(O)c1ccc(Br)nc1,,C1CCOC1,CCOCC,[Li]CCCC,,test
US20040092507A1,C1CCNCC1.CC(C)(C)OC(=O)N1CCN(c2ccccc2C(=O)O)CC1>>O=C(c1ccccc1N1CCNCC1)N1CCCCC1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20060058325A1,COc1cc2c(Nc3ccc(NC(=O)c4cccc(Cl)c4)nc3)ncnc2cc1O.O=C([O-])COCCCCBr>>COc1cc2c(Nc3ccc(NC(=O)c4cccc(Cl)c4)nc3)ncnc2cc1OCCCCOC(C)=O,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20040058978A1,CC(=O)OC(C)=O.Nc1cccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)c1>>CC(=O)Nc1cccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)c1,,CC(=O)O,,,,test
US20160046617A1,COC(=O)CCNC(=O)c1cc(-c2cc(Cl)ccc2O)ccn1.COc1ccc(CN(c2ncns2)S(=O)(=O)c2cc(Cl)c(F)cc2F)c(OC)c1>>COC(=O)CCNC(=O)c1cc(-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)N(Cc3ccc(OC)cc3OC)c3ncns3)cc2Cl)ccn1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100197683A1,BrCC1CC1.CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)[nH]c2ncnn12>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(CC2CC2)c2ncnn12,,CCOC(C)=O,,CC(=O)N(C)C,O=C([O-])[O-].[K+].[K+],test
US20070142328A1,CCN.CCOC(=O)C(C#N)=NNc1ccccc1Br>>CCNC(=O)C(C#N)=NNc1ccccc1Br,,CO,,CCN(CC)CC,O,test
US20120108567A1,CC(=O)Nc1ccc(Br)c(Cl)c1.CI>>CC(=O)N(C)c1ccc(Br)c(Cl)c1,,C1CCOC1,,[H-].[Na+],,test
US06323173B1,Cc1ccc2c(c1)C(=O)C(C)C2.Cc1ccccc1>>Cc1ccc2c(c1)CC(C)(CO)C2,,O,,O=C([O-])[O-].[K+].[K+],,test
US20160016908A1,CC(=O)N1c2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc2[C@H](Nc2cnc(C)cn2)[C@@H](C)[C@@H]1C.Cl>>CC(=O)N1c2ccc(C3CCNCC3)cc2[C@H](Nc2cnc(C)cn2)[C@@H](C)[C@@H]1C.Cl,,C1COCCO1,,,,test
US20160028021A1,Clc1cccc(-c2nc(Cl)nc(-c3cccc(Cl)c3)n2)c1.OB(O)c1ccc(-c2ccccc2)cc1>>Clc1cccc(-c2nc(-c3ccc(-c4ccccc4)cc3)nc(-c3cccc(Cl)c3)n2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20090047246A1,Clc1ccc2scc(CBr)c2c1.N#CCc1c[nH]c2ccccc12>>N#CCc1cn(Cc2csc3ccc(Cl)cc23)c2ccccc12,,C1CCOC1,CCOC(C)=O,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20110224204A1,O=S(=O)(Oc1ccc(F)cc1-c1ccc(OCc2ccc3ccccc3n2)cc1)C(F)(F)F.OB(O)c1ccncc1>>Fc1ccc(-c2ccncc2)c(-c2ccc(OCc3ccc4ccccc4n3)cc2)c1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20050107364A1,CCCCC1(CCCC)C(=O)C(=C(SC)SC)C(=O)c2ccccc21.COCOCc1csc(N)c1S(N)(=O)=O>>CCCCC1(CCCC)C(=O)C(C2=NS(=O)(=O)c3c(COCOC)csc3N2)=C(O)c2ccccc21,,Cc1ccccc1,,,,test
US04727180,CI.CN(C)C(=O)CCc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1[N+](=O)[O-]>>COC(c1ccc(CCC(=O)N(C)C)c([N+](=O)[O-])c1)(C(F)(F)F)C(F)(F)F,,CN(C)C=O,O,CCO,[H-].[Na+],test
US04652563,NCC(O)COc1ccc(CCOCC2CC2)cc1.O=C(O)[C@@H](O)c1ccccc1>>NCC(O)COc1ccc(CCOCC2CC2)cc1.O=C([O-])C(O)c1ccccc1,,CO,O,,,test
US20130045964A1,CN1CCOCC1.O=C(O)CCNC(=O)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1>>O=C(NCCC(=O)N1CC(O)C1)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20110152273A1,Cn1cc(-c2nc(N[C@@H]3CCCC[C@@H]3NC(=O)OC(C)(C)C)c(F)c3c2C(=O)N(C(=O)OC(C)(C)C)C3)cn1>>Cn1cc(-c2nc(N[C@@H]3CCCC[C@@H]3N)c(F)c3c2C(=O)NC3)cn1,,CC(C)O,,Cl,,test
US20130150394A1,COCON1C(=O)C(c2c(C)cc(Br)cc2C)=C(O)C12CCN(OC)CC2.OB(O)c1ccc(Cl)cc1>>COCON1C(=O)C(c2c(C)cc(-c3ccc(Cl)cc3)cc2C)=C(O)C12CCN(OC)CC2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US05025031,O=C=NS(=O)(=O)Cl.Oc1ccccc1F>>NS(=O)(=O)Oc1ccccc1F,,Cc1ccccc1,,c1ccccc1,,test
US20070032515A1,CCOC(=O)C(C)C.COc1ccc(CC#N)cc1OC>>COc1ccc(C(C#N)C(=O)C(C)C)cc1OC,,CCO,,C,C[O-].[Na+],test
US20160152596A1,CC(C)OC(=O)/C(=C/n1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)c1cccnc1>>O=C(O)/C(=C/n1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)c1cccnc1,,C1CCOC1,O,Cl,[Li]O,test
US20050203296A1,FC(F)(F)c1ccccc1CC[C@H]1CN(Cc2ccccc2)CCN1Cc1ccccc1>>FC(F)(F)c1ccccc1CC[C@H]1CNCCN1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20060030613A1,CC(C)(C)c1ccc(CN(CCO)C(=O)c2cccc3cc[nH]c23)cc1.Oc1ccccc1Cl>>CC(C)(C)c1ccc(CN(CCOc2ccccc2Cl)C(=O)c2cccc3cc[nH]c23)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140343294A1,O=C(CCCl)c1cccs1>>C=CC(=O)c1cccs1,,CCOCC,,CCN(CC)CC,,test
US20050032786A1,COC(=O)c1ccccc1S.N#Cc1ccnc(C#N)c1>>N#Cc1ccnc(-c2nc(=O)c3ccccc3s2)c1,,Cc1ccccc1,,CCN(CC)CC,,test
US06479531B1,O=C(COC12CC3CC(CC(C3)C1)C2)CC(=O)Nc1cccc(C(=O)OCc2ccccc2)c1.O=N[O-]>>O=C(COC12CC3CC(CC(C3)C1)C2)C(=NO)C(=O)Nc1cccc(C(=O)OCc2ccccc2)c1,,C1CCOC1,CC(=O)O,O,,test
US20100048610A1,CCCc1ncccc1O.II>>CCCc1nc(I)ccc1O,,CCO,O,,,test
US20120010183A1,CC(C)(C)OC(=O)OC(C)(C)C.O=C(O)c1c(F)cc(F)c(F)c1F>>CC(C)(C)OC(=O)c1c(F)cc(F)c(F)c1F,CN(C)c1ccncc1,CC(C)(C)O,,,,test
US20010056094A1,CCOc1cccc(-c2ccc(F)c([N+](=O)[O-])c2)c1.COC(=O)CC(=O)OC>>CCOc1cccc(-c2ccc(C(C(=O)OC)C(=O)OC)c([N+](=O)[O-])c2)c1,,CS(C)=O,,[H-].[Na+],,test
US20090018132A1,C[C@@H](OCC1(c2ccc(F)cc2)CCN(C(=O)OC(C)(C)C)CC1)c1cc(Cl)cc2c(Cl)n[nH]c12>>C[C@@H](OCC1(c2ccc(F)cc2)CCNCC1)c1cc(Cl)cc2c(Cl)n[nH]c12,,O=C(O)C(F)(F)F,,,,test
US03976643,N=C(N)Nc1c(Cl)cccc1Cl>>N=C(N)Nc1c(Cl)cccc1Cl,,[Na+],[OH-],Cl,,test
US06872718B1,C=C(C)CCl.Cc1cc(O)c(C)c2c1N(C=O)CC2>>C=C(C)COc1cc(C)c2c(c1C)CCN2C=O,,CN(C)C=O,O,[I-].[K+],,test
US20090111819A1,CCn1nc(-c2ccccc2)c(C(C)=O)c([N+](=O)[O-])c1=O.Nc1cccc2cnccc12>>CCn1nc(-c2ccccc2)c(C(C)=O)c(Nc2cccc3cnccc23)c1=O,,CCO,,,,test
US20040142999A1,COC(=O)[C@@H](O)CCc1ccccc1.O=C(CCl)N1CCOCC1>>COC(=O)[C@H](CCc1ccccc1)OCC(=O)N1CCOCC1,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20160214956A1,BrCCCOC1CCCCO1.CCOC(=O)c1cnn(-c2cccc(-c3ccccc3CCc3ccc(O)cc3C)n2)c1C(F)(F)F>>CCOC(=O)c1cnn(-c2cccc(-c3ccccc3CCc3ccc(OCCCOC4CCCCO4)cc3C)n2)c1C(F)(F)F,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4ccsc4)nc(Cl)c3n2)cc1.Nc1ccc(N2CCSCC2)cc1>>c1cc(-c2nc(Nc3ccc(N4CCSCC4)cc3)c3[nH]ncc3n2)cs1,C1COCCO1,CO,,Cl,,test
US20120283216A1,C#Cc1ccc2ccc(OC(OC)C(=O)O)cc2c1.COCC(C)(C)N>>C#Cc1ccc2ccc(OC(OC)C(=O)NC(C)(C)COC)cc2c1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US04564609,C(=NC1CCCCC1)=NC1CCCCC1.CO.N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1.O>>O=C1C[C@@H](C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N2CCC[C@H]2C(=O)OCc2ccccc2)N1,,ClCCl,,On1nnc2ccccc21,,test
US20110172187A1,CCO/C=C/c1cc(NC(=O)C(F)(F)F)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2>>CCOCCc1cc(N)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2,[Pd],CO,N,,,test
US20070027318A1,COc1cc2nccc(Oc3ccc(N)c(C)c3C)c2cc1OC.Cc1ccccc1N=C=O>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccccc4C)c(C)c3C)c2cc1OC,,ClC(Cl)Cl,,CO,,test
US20120269766A1,C#CCOCCOCCOCCOCCN.O=[N+]([O-])c1ccc(Cl)c([N+](=O)[O-])c1>>C#CCOCCOCCOCCOCCNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-],,CCO,,CCN(CC)CC,,test
US20130338141A1,COC(=O)c1nc(C(CCC(C)(C)CO)N(C)C(=O)OC(C)(C)C)[nH]c(=O)c1O.Cc1cc(CN)ccc1F>>Cc1cc(CNC(=O)c2nc(C(CCC(C)(C)CO)N(C)C(=O)OC(C)(C)C)[nH]c(=O)c2O)ccc1F,,CC(C)O,,,,test
US20050282808A1,COC(=O)c1ccc2oc(C(=O)Nc3ccc(Cl)cn3)c(NC(=O)[C@@H]3CC[C@@H](NC(C)C)CC3)c2c1>>CC(C)N[C@@H]1CC[C@@H](C(=O)Nc2c(C(=O)Nc3ccc(Cl)cn3)oc3ccc(C(=O)O)cc23)CC1,,C1CCOC1,CO,[Na+].[OH-],,test
US06028213,CCCO.Cc1ccccc1.O=C1OC(=O)[C@H]2CCC[C@@H]1C2>>CCCOC(=O)[C@@H]1CCC[C@H](C(=O)OCCC)C1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US06265381B1,C1COCCN1.CCOC(=O)c1ccc(N=C=O)cc1>>CCOC(=O)c1ccc(NC(=O)N2CCOCC2)cc1,,Cc1ccccc1,,,,test
US20090111789A1,CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)OC(C)(C)C)CC1.Cl>>CCOc1cc(C(C)(C)C)ncc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)O)CC1.Cl,,C1CCOC1,CO,[Li+].[OH-],,test
US20150158858A1,CC(C)(C)[Si](C)(C)OCc1ccc(CC(=O)O)s1.COc1ccc([C@@H](O)Cc2c(Cl)c[n+]([O-])cc2Cl)cc1OC>>COc1ccc([C@H](Cc2c(Cl)c[n+]([O-])cc2Cl)OC(=O)Cc2ccc(CO[Si](C)(C)C(C)(C)C)s2)cc1OC,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20020151595A1,CO.N#Cc1ccc(OCc2ccccc2)c(CC(=O)O)c1>>COC(=O)Cc1cc(C#N)ccc1OCc1ccccc1,,ClCCl,,O=S(Cl)Cl,,test
US05952511,Cc1cccc2c1NC(=O)C2=O.NOCc1ccccc1>>Cc1cccc2c1NC(=O)C2=NOCc1ccccc1,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20030232832A1,CC(C)(C)OC(=O)NCCCNC(c1nn2c(Cl)ccc2c(=O)n1Cc1ccccc1)C1CC1.Cc1ccc(C(=O)Cl)cc1>>Cc1ccc(C(=O)N(CCCNC(=O)OC(C)(C)C)C(c2nn3c(Cl)ccc3c(=O)n2Cc2ccccc2)C2CC2)cc1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US04423047,CSc1ncc(Cl)cn1.O=S(=O)(Cl)Cl>>ClCSc1ncc(Cl)cn1,,ClCCl,,,,test
US04868061,C=CCOC(=O)N(CC(=O)OC)C(=O)Nc1ccc(C(C)=NO)cc1>>C=CCOC(=O)N1CC(=O)N(c2ccc(C(C)=NO)cc2)C1=O,,CO,,CO[Na],,test
US20090035323A1,CC(C)(C)OC(=O)NCCO.CCOCc1nc2cnc3ccccc3c2n1O>>CCOCc1nc2cnc3ccccc3c2n1OCCNC(=O)OC(C)(C)C,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140163219A1,COc1ccc2oc(C(C)=O)c(N)c2c1Cl.O=Cc1ccccc1>>COc1ccc2oc(C(=O)C=Cc3ccccc3)c(N)c2c1Cl,,CO,,O,[Na+].[OH-],test
US05354549,COc1ccc(C(=O)O)cc1C.ClCSc1ccccc1>>COc1ccc(C(=O)OCSc2ccccc2)cc1C,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20160231635A1,COC(=O)c1cccc(C(=O)OC)n1>>OCc1cccc(CO)n1,,CCO,,[BH4-].[Na+],,test
US20130338367A1,CC(C)(C)O.O=C(O)c1cn(-c2cccnc2)nc1Br.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)Nc1cn(-c2cccnc2)nc1Br,,Cc1ccccc1,,CCN(CC)CC,,test
US05194446,NS(=O)(=O)Cl.OCCCc1ccccc1>>NS(=O)(=O)OCCCc1ccccc1,,CC#N,,CCN(CC)CC,,test
US20160005546A1,CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O.CI>>COc1c(C(C)(C)C)cc(C=O)cc1C(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20160185778A1,C1CC2CC2(c2n[nH]c3c2CNCC3)C1.O=C=Nc1cccc(Cl)c1>>O=C(Nc1cccc(Cl)c1)N1CCc2[nH]nc(C34CCCC3C4)c2C1,,ClCCl,,O,,test
US20040132727A1,COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.O=C(N=C=S)c1ccc(Cl)cc1>>COc1cc2ncnc(Oc3ccc(NC(=S)NC(=O)c4ccc(Cl)cc4)cc3)c2cc1OC,,Cc1ccccc1,,CCO,,test
US20050113580A1,BrCCCCBr.COc1cccc(N)c1>>COc1cccc(N2CCCC2)c1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20070082907A1,CSc1ccc(C(F)(F)F)cc1C(C)=O.O=C(O)CBr>>Cc1c(C(=O)O)sc2ccc(C(F)(F)F)cc12,,CC(=O)O,,O,,test
US06043242,Cc1c(SCCCSc2ccc3ncc([N+](=O)[O-])n3n2)ccnc1CCl.Sc1ncccn1>>Cc1c(SCCCSc2ccc3ncc([N+](=O)[O-])n3n2)ccnc1CSc1ncccn1,,CC(C)O,,CCN(CC)CC,,test
US06191124B1,OCc1cnc2sc3c(n12)CCCCCC3>>O=Cc1cnc2sc3c(n12)CCCCCC3,O=[Mn]=O,Cc1ccccc1,,,,test
US04548932,CCOC(=O)[C@H](CCC1CCCCC1)N[C@H]1COc2ccccc2N(CC(=O)OC(C)(C)C)C1=O>>CC(C)(C)OC(=O)CN1C(=O)[C@@H](N[C@@H](CCC2CCCCC2)C(=O)O)COc2ccccc21,,CCO,O,[Na+].[OH-],,test
US20040181064A1,CC(=O)Nc1ccc(Br)c(F)c1C.N#C[Cu]>>CC(=O)Nc1ccc(C#N)c(F)c1C,,CN(C)C=O,,,,test
US20030087902A1,COc1ccc(-c2c(C(=O)O)n(Cc3cccc(C(F)(F)F)c3)c3ccccc23)cc1.NS(=O)(=O)c1ccccc1>>COc1ccc(-c2c(C(=O)NS(=O)(=O)c3ccccc3)n(Cc3cccc(C(F)(F)F)c3)c3ccccc23)cc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20070185179A1,C=CCBr.O=C1Nc2ccccc2C1=O>>C=CCN1C(=O)C(=O)c2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150291554A1,NC(=O)c1c(-c2ccc(Oc3ccc(Cl)cc3)cc2)nn([C@@H]2CCCNC2)c1N.O=C(O)/C=C/CF>>NC(=O)c1c(-c2ccc(Oc3ccc(Cl)cc3)cc2)nn([C@@H]2CCCN(C(=O)/C=C/CF)C2)c1N,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04873244,CNC.Cn1c(=O)c2c(Cl)cccc2n2cnc(-c3noc(C4CC4)n3)c12>>CN(C)c1cccc2c1c(=O)n(C)c1c(-c3noc(C4CC4)n3)ncn21,,CN(C)C=O,,,,test
US20130338196A1,CC(C)(C)[Si](C)(C)Cl.COC(=O)C(O)C1CCc2cc(Oc3ccccc3)ccc2C1>>COC(=O)C(O[Si](C)(C)C(C)(C)C)C1CCc2cc(Oc3ccccc3)ccc2C1,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US20110021489A1,CCOC(=O)C1CNCC(c2ccc(CC)cc2)C1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCOC(=O)C1CC(c2ccc(CC)cc2)CN(C(=O)Oc2ccc([N+](=O)[O-])cc2)C1,,ClCCl,,CCN(CC)CC,,test
US20080293771A1,CC(C)(C)OC(=O)N1CC[C@@H](N)C1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)N1CC[C@@H](NC(=O)OCc2ccccc2)C1,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,,test
US20060264403A1,CC(C)(C)OC(=O)N1C(C)(C)OC[C@@]1(CO)CCc1ccc(O)cc1.Fc1cccc(OCCBr)c1>>CC(C)(C)OC(=O)N1C(C)(C)OC[C@@]1(CO)CCc1ccc(OCCOc2cccc(F)c2)cc1,,CN(C)C=O,,CCOC(C)=O,O,test
US20140343079A1,CC(=O)OC(C)=O.O=Cc1ccc(O)c(Br)c1>>CC(=O)Oc1ccc(C=O)cc1Br,CN(C)c1ccncc1,,,,,test
US20090105227A1,COC(=O)c1cc2c(s1)c(C1CCCCC1)c(Br)n2C(=O)OC(C)(C)C>>COC(=O)c1cc2[nH]c(Br)c(C3CCCCC3)c2s1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120258946A1,Nc1ccc(N2CC(O)C2)c(F)c1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ccc(N2CC(O)C2)c(F)c1)Oc1ccccc1,,CC(C)=O,,c1ccncc1,,test
US20140179666A1,C[C@@H]1CN(Cc2ccccc2)[C@@H](CCl)CN1C(=O)OC(C)(C)C.O=C1NCCO1>>C[C@@H]1CN(Cc2ccccc2)[C@@H](CN2CCOC2=O)CN1C(=O)OC(C)(C)C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150329549A1,CI.Cc1cc(=O)n(-c2ccccc2F)[nH]1>>Cc1cc(=O)n(-c2ccccc2F)n1C,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20120214762A1,Nc1nccc(-n2c(C(Cl)(Cl)Cl)nc3ccc(Br)cc32)n1.OCC(F)(F)F>>Nc1nccc(-n2c(OCC(F)(F)F)nc3ccc(Br)cc32)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120277229A1,CC1CCN(c2ccc([N+](=O)[O-])c(N)c2)CC1>>CC1CCN(c2ccc(N)c(N)c2)CC1,[Pd],CCO,,[H][H],,test
US20020045122A1,CC(C)(C)C(=O)CBr.CC(C)=O.Oc1sc(O)c(O)c1O>>CC(C)(C)C(=O)C[S+]1CCCC1.[Br-],,CC(C)=O,,,,test
US20100317659A1,COc1cc(C(=O)c2nc(Cl)c3ccccc3n2)ccc1F.Cc1cc(N)n[nH]1>>COc1cc(C(=O)c2nc(Nc3cc(C)[nH]n3)c3ccccc3n2)ccc1F,,CN(C)C=O,O,CCN(C(C)C)C(C)C,[I-].[K+],test
US20100240634A1,CI.Cc1cc(C(=O)O)cc2c1-c1ccccc1C2=O>>COC(=O)c1cc(C)c2c(c1)C(=O)c1ccccc1-2,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20120010188A1,COc1cccc(C(=O)CBr)c1.Nc1ccc(Br)cn1>>COc1cccc(-c2cn3cc(Br)ccc3n2)c1,,CCO,,[Na+].[OH-],,test
US20060084663A1,CCOC(=O)COc1ccc(SCc2sc(-c3ccc(C(F)(F)F)cc3)nc2CCc2ccccc2)cc1C>>Cc1cc(SCc2sc(-c3ccc(C(F)(F)F)cc3)nc2CCc2ccccc2)ccc1OCC(=O)O,,C1CCOC1,,Cl,[Li+].[OH-],test
US05098462,CC(=O)c1ncccc1C(=O)O.NNC(=O)Nc1ccccc1>>CC(=O)c1ncccc1C(O)=NNC(=O)Nc1ccccc1,,CO,,,,test
US05266570,C[C@@H]1CNC[C@@H](C)O1.O=C1CCN(CC23CC(c4ccccc42)c2ccc(Cl)cc23)CC1>>C[C@@H]1CN(C2CCN(CC34CC(c5ccccc53)c3ccc(Cl)cc34)CC2)C[C@@H](C)O1,,Cc1ccccc1,,,,test
US20110190255A1,CCOC(=O)c1onc(-c2ccccn2)c1C(F)(F)F>>O=C(O)c1onc(-c2ccccn2)c1C(F)(F)F,,CO,O,Cl,[Li+].[OH-],test
US20120309701A1,CN.CNC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)cc(C(=O)NC)c1.COC(=O)c1cc(Br)cc(C(=O)OC)c1>>CN(C)C(=O)c1cc(Br)cc(C(N)=O)c1,,CCO,,,,test
US20080269219A1,CCOC(=O)CCCc1oc(-n2ccnc2C)nc1-c1ccc(Cl)s1>>Cc1nccn1-c1nc(-c2ccc(Cl)s2)c(CCCCO)o1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050143381A1,C[Mg]Br.O=c1n(Cc2ccc(C(F)(F)F)cc2)nc2c(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)cnn12>>CC1Nn2c(nn(Cc3ccc(C(F)(F)F)cc3)c2=O)C(c2ccc(Cl)cc2)=C1c1ccc(Cl)cc1,,C1CCOC1,,CO,,test
US20060199829A1,CI.COC(=O)c1cnc(N2CCc3c([nH]c4ccccc34)C2)nc1>>COC(=O)c1cnc(N2CCc3c(n(C)c4ccccc34)C2)nc1,,CCOC(C)=O,CN(C)C=O,CC(C)(C)[O-].[K+],,test
US20160009667A1,CS(=O)(=O)Cl.Nc1noc2cc(OCC3CCC(F)(F)CC3)c(C3CC3)cc12>>CS(=O)(=O)Nc1noc2cc(OCC3CCC(F)(F)CC3)c(C3CC3)cc12,,ClCCl,,CCN(CC)CC,,test
US20150329523A1,COCCOCCOCCOCCOCCOCCOCCOc1cc(N)cc(OC)c1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)cc1>>COCCOCCOCCOCCOCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)nn4-c4ccc(C)cc4)c4ccccc34)n2)cc(OC)c1,,C1CCOC1,,CN(C)C=O,O=C([O-])O.[Na+],test
US20150175599A1,COc1ccc2[nH]c(C)cc2c1.FC(F)(F)c1cnc(CCl)c(Cl)c1>>COc1ccc2c(c1)cc(C)n2Cc1ncc(C(F)(F)F)cc1Cl,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US04057647,C=[N+]=[N-].CC(=CC(=O)O)c1ccc(-c2ccc(F)cc2F)cc1>>COC(=O)C=C(C)c1ccc(-c2ccc(F)cc2F)cc1,,C1CCOC1,,,,test
US06881736B1,CCO.COc1ccc(C[C@@H](CC(=O)N2C(=O)N(C)C(C)C2c2ccccc2)c2cccnc2)cc1>>CCOC(=O)C[C@H](Cc1ccc(OC)cc1)c1cccnc1,,C1CCOC1,,C,C[O-].[Na+],test
US20120010228A1,CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)N(Cc1cccc(C(=O)OCC(=O)N3CCCCC3)c1)CN2c1ccccc1>>O=C(OCC(=O)N1CCCCC1)c1cccc(CN2CN(c3ccccc3)C3(CCNCC3)C2=O)c1,,C1COCCO1,,Cl,,test
US20050191238A1,CC(C)(C)[Si](C)(C)Cl.CCC(O)CO>>CCC(O)CO[Si](C)(C)C(C)(C)C,,ClCCl,,CN(C)C=O,c1c[nH]cn1,test
US20100234344A1,Cc1cc(Cl)c2cccc(O)c2n1.c1c[nH]cn1>>Cc1cc(-n2ccnc2)c2cccc(O)c2n1,,C1COCCO1,,,,test
US20030073839A1,O=C(O)CC1CC2CCC1C2>>OCCC1CC2CCC1C2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04663347,CCOC(=O)c1oc2cccc(OCC(C)=O)c2c1C>>CCOC(=O)c1oc2cccc(OCC(C)O)c2c1C,,CCO,,[BH4-].[Na+],,test
US20060025474A1,CCC(CC)(c1ccc(O)c(C)c1)c1ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1.O=C1CCC[C@H](CO)O1>>CCC(CC)(c1ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1ccc(OC[C@H]2CCCC(=O)O2)c(C)c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150045339A1,COCCC(CCOC)(CNC(=O)OCC1c2ccccc2-c2ccccc21)NC(=O)OC(C)(C)C>>COCCC(N)(CCOC)CNC(=O)OCC1c2ccccc2-c2ccccc21,,ClCCl,O=C(O)C(F)(F)F,,,test
US05877190,C=CC[Sn](CCCC)(CCCC)CCCC.COc1cc(Br)cc2ccoc12>>C=CCc1cc(OC)c2occc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US20120252801A1,CCN1CC(C)(C)OC(=O)C1CC(=O)O.NCC(F)(F)F>>CCN1CC(C)(C)OC(=O)C1CC(=O)NCC(F)(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120040020A1,CCC(=O)NC1CC=C(c2cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(-c3nnc(-c4ccc(CN(C)C(=O)OC(C)(C)C)cc4)o3)n2)CC1>>CCC(=O)NC1CC=C(c2cnc(N)c(-c3nnc(-c4ccc(CNC)cc4)o3)n2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150099777A1,COc1c(C=O)ccc(-c2ccc(F)cc2)c1F>>O=Cc1ccc(-c2ccc(F)cc2)c(F)c1O,,CC(=O)O,,Br,,test
US20070197604A1,CC1CCCCN1.Cc1oc(-c2ccc(Br)cc2)nc1CCOS(C)(=O)=O>>Cc1oc(-c2ccc(Br)cc2)nc1CCN1CCCCC1,,C1CCOC1,,ClCCl,,test
US20040053913A1,O=C(O)C1CCCCN1.O=N[O-]>>O=NN1CCCCC1C(=O)O,,O,,Cl,,test
US20130274287A1,CCN=C=O.N#Cc1ccc(-c2cncc3c2CCCC3O)cc1>>CCNC(=O)OC1CCCc2c(-c3ccc(C#N)cc3)cncc21,CN(C)c1ccncc1,CO,ClCCl,CCN(CC)CC,O=C([O-])O.[Na+],test
US20070244164A1,CC(C)(C)[Si](C)(C)OCCC1(S(=O)(=O)Cl)CC1.Cc1c(=O)n(C)cc2[nH]c(=O)n(-c3ccc(I)cc3F)c12>>Cc1c(Nc2ccc(I)cc2F)c(NS(=O)(=O)C2(CCO)CC2)cn(C)c1=O,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20080280911A1,CCn1nccc1N.Cc1cc(I)cc2c(Cl)c(C(N)=O)nnc12>>CCn1nccc1Nc1c(C(N)=O)nnc2c(C)cc(I)cc12,,CC#N,,Cl,c1ccncc1,test
US20040242573A1,II.c1ccc(N2CCCC2)cc1>>Ic1ccc(N2CCCC2)cc1,,CCO,O,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20030171411A1,CC(C)S.COC(=O)C(Br)c1ccc(Cl)c(Cl)c1.Nc1nccs1>>CC(C)SC(C(=O)Nc1nccs1)c1ccc(Cl)c(Cl)c1,,C1CCOC1,,,,test
US20100216764A1,CCOC(=O)c1cnn(-c2cccc(-c3cccc(F)c3OCc3ccc(C4CCN(C(=O)OC(C)(C)C)CC4)cc3)n2)c1C(F)(F)F>>CCOC(=O)c1cnn(-c2cccc(-c3cccc(F)c3OCc3ccc(C4CCNCC4)cc3)n2)c1C(F)(F)F,,CC(=O)O,O,,,test
US20120115856A1,Cc1nc2cc(-c3nc4ccc([N+](=O)[O-])cc4o3)ccc2n1C1CCOCC1>>Cc1nc2cc(-c3nc4ccc(N)cc4o3)ccc2n1C1CCOCC1,[Pd],CO,,[H][H],,test
US04665075,CC(=O)OC(C)=O.Nc1ccc2c(=O)n(CCCCN3CCC(C(=O)c4ccc(F)cc4)CC3)c(=O)[nH]c2c1>>CC(=O)Nc1ccc2c(=O)n(CCCCN3CCC(C(=O)c4ccc(F)cc4)CC3)c(=O)[nH]c2c1,,CC(=O)O,,,,test
US20100152445A1,CC(C)(C)OC(=O)N1CC[C@H](Oc2ccc(N)cc2)C1.O=C(O)c1nc(-c2ccccc2)oc1C(F)(F)F>>CC(C)(C)OC(=O)N1CC[C@H](Oc2ccc(NC(=O)c3nc(-c4ccccc4)oc3C(F)(F)F)cc2)C1,,CN(C)C=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20020061537A1,BrC(Br)(Br)Br.CCCCCCCCCCCCCCCCC(O)C(O)C(O)CCCCCCCCCCCCCCCC>>CCCCCCCCCCCCCCCCOC(CBr)C(O)CCCCCCCCCCCCCCCC,,Cc1ccccc1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060293319A1,O=C1Nc2cc(Cl)ccc2/C1=C/c1cccc(Cl)c1>>O=C1Nc2cc(Cl)ccc2C1Cc1cccc(Cl)c1,,CO,,[BH4-].[Na+],,test
US20030195199A1,CCCCCCCCNC(=O)Nc1sc(C(=O)OC(C)CCCCCC)c(C)c1C(=O)OC(C)(C)C>>CCCCCCCCCCCCCCN=C=O,,CCOC(C)=O,,,,test
US04349684,COC(=O)CCCCCCCBr.COc1ccc(-n2c(-c3ccccc3)c[nH]c2=O)cc1>>COC(=O)CCCCCCCn1cc(-c2ccccc2)n(-c2ccc(OC)cc2)c1=O,,CN(C)C=O,,[H-].[Na+],,test
US06265411B1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCOCC1.NC(=O)c1ccc2c(c1)CC(=O)N2>>COc1cc2c(C3C(=O)Nc4ccc(C(N)=O)cc43)ncnc2cc1OCCCN1CCOCC1.Cl,,CN(C)C=O,,[H-].[Na+],,test
US06479512B1,CCOC(=O)c1cc2cc(Cl)ccc2[nH]c1=O.Nc1ccccc1N>>O=c1[nH]c2ccc(Cl)cc2cc1-c1nc2ccccc2[nH]1,,,,O=C([O-])O.[Na+],,test
US20100222303A1,CCOC(CN(Cc1cccc(OC)c1OC)C(=O)C(Cc1ccc(OC(C)(C)C)cc1)NC(=O)CC(C)NC(=O)NCc1ccccc1)OCC>>COc1cccc(CN2CC3N(C(=O)NCc4ccccc4)C(C)CC(=O)N3C(Cc3ccc(O)cc3)C2=O)c1OC,,O=CO,,,,test
US20060142333A1,O=C(Nc1ccc2cccnc2c1)c1ccc(Cl)nc1.OB(O)c1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc2cccnc2c1)c1ccc(-c2ccc(C(F)(F)F)cc2)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US20020052513A1,COc1ccc(N2CCN(CC(C)(C)[N+](=O)[O-])CC2)cc1>>COc1ccc(N2CCN(CC(C)(C)N)CC2)cc1,[Pd],CCO,,,,test
US20060025614A1,CCOC(Cc1ccccc1C)=NC#N.C[C@@H](N)c1ccccc1>>Cc1ccccc1CC(=NC#N)N[C@H](C)c1ccccc1,,CCO,,,,test
US20130142739A1,C1CCNCC1.C[S+]([O-])CCCCN=C=S>>NC(=S)N1CCCCC1,,ClCCl,,,,test
US05912245,O=c1[nH]c2cc([N+](=O)[O-])c(S(=O)(=O)Cl)cc2[nH]c1=O.[NH4+]>>NS(=O)(=O)c1cc2[nH]c(=O)c(=O)[nH]c2cc1[N+](=O)[O-],,O,,CC(=O)O,,test
US07396844B1,CCOC(=O)c1ccc(C2=NCCN2)cc1>>CCOC(=O)c1ccc(-c2ncc[nH]2)cc1,[Pd],CCOC(C)=O,Cc1ccccc1,,,test
US20030069434A1,CN.Cc1ccc(S(=O)(=O)[O-])c(CCCCCCC(F)(F)C(F)(F)F)c1>>CNCCCCCCC(F)(F)C(F)(F)F,,C1CCOC1,,,,test
US05998412,CCOC(=O)CNCc1ccccc1.O=S(=O)(Cl)Cl>>CCOC(=O)CN(Cc1ccccc1)S(=O)(=O)Cl,,ClCCl,,CCN(CC)CC,,test
US20070161640A1,CCOCC.N[C@@H](CC(=O)O)C(=O)O.OCc1ccccc1.c1ccccc1>>N[C@@H](CC(=O)OCc1ccccc1)C(=O)OCc1ccccc1,,CCOCC,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05324747,CCCCCCCCCCNC(=O)c1cc(C(=O)NCCCCCCCCCC)cc([N+](=O)[O-])c1>>CCCCCCCCCCNC(=O)c1cc(N)cc(C(=O)NCCCCCCCCCC)c1,[Pd],C1CCOC1,,,,test
US20060122064A1,CCCOc1ccc(CCC(=O)OCC)cc1OC>>CCCOc1ccc(CCC(=O)O)cc1OC,,CCO,,[Na+].[OH-],,test
US20100190763A1,CCOC(=O)c1ccc(N2CCN(Cc3cnc4c(c3)NC(=O)[C@@H]3CCCN43)CC2)nc1>>O=C(O)c1ccc(N2CCN(Cc3cnc4c(c3)NC(=O)[C@@H]3CCCN43)CC2)nc1,,C1COCCO1,,[Li+].[OH-],,test
US20130004420A1,CCCC[Sn](CCCC)(CCCC)c1ccc(CNC)cc1C(OCOC)(C(F)(F)F)C(F)(F)F.O=C(CCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O>>CCCC[Sn](CCCC)(CCCC)c1ccc(CN(C)C(=O)CCN2C(=O)C=CC2=O)cc1C(OCOC)(C(F)(F)F)C(F)(F)F,,CC#N,,,,test
US20130123522A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@H](CO)C(=O)NCc1ccccc1>>CC(C)(C)OC(=O)N[C@H](CO)C(=O)NCc1ccccc1,,CCOC(C)=O,,CCN(CC)CC,,test
US20150005289A1,CC(C)(C)OC(=O)N1CCC(c2ccc3nc(O)cc(=O)n3c2)CC1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCC(c2ccc3nc(OS(=O)(=O)C(F)(F)F)cc(=O)n3c2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20030045728A1,CCOC(=O)CC(c1ccccc1)c1c[nH]c2cc(OCC(=O)OC(C)(C)C)ccc12.O=C(O)C(F)(F)F>>CCOC(=O)CC(c1ccccc1)c1c[nH]c2cc(OCC(=O)O)ccc12.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20150336895A1,CCSc1ccccc1C(=O)Nc1ccc(C(F)(F)F)cn1.CI>>CCSc1ccccc1C(=O)N(C)c1ccc(C(F)(F)F)cn1,,C1CCOC1,,[H-].[Na+],,test
US20140323470A1,CN1CCC[C@@H]1c1nnc2ccc(O[C@@H]3CC[C@H](N)c4ccccc43)cn12.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc([C@H]5CCCN5C)n4c3)c3ccccc32)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20020137946A1,O=C(O)[C@H]1C[C@H](F)CN1C(=O)Nc1cc(NS(=O)(=O)CCl)c(Cl)cc1F>>O=C1[C@H]2C[C@H](F)CN2C(=O)N1c1cc(NS(=O)(=O)CCl)c(Cl)cc1F,CN(C)C=O,ClCCl,,O=S(Cl)Cl,,test
US20120232051A1,COc1cc(F)ccc1-c1ccncc1N(CC(F)F)C(=O)c1cc(C(F)(F)F)nc(C(F)(F)F)c1.Cc1ccccc1B(O)O>>Cc1ccccc1-c1ccncc1NCC(F)F,,CCCCCCC,CCOC(C)=O,,,test
US20110112103A1,CC(C)(C)OC(=O)c1nc(CC2CCN(C(=O)OC(C)(C)C)CC2)nc(O)c1OCc1ccccc1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)c1nc(CC2CCN(C(=O)OC(C)(C)C)CC2)nc(OS(=O)(=O)C(F)(F)F)c1OCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US04275001,Cc1ccc(S(=O)(=O)Cl)cc1.N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O>>Cc1ccc(S(=O)(=O)n2cnc(C[C@H](NC(=O)[C@@H](N)CCC(=O)O)C(=O)O)c2)cc1,,C1COCCO1,O,O=C([O-])O.[Na+],,test
US20110301167A1,C1COCCN1.Cc1ccccc1-n1nc2c3ccccc3n(Cc3ccc(Br)nc3)nc-2c1=O>>Cc1ccccc1-n1nc2c3ccccc3n(Cc3ccc(N4CCOCC4)nc3)nc-2c1=O,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070021403A1,CC(C)(C)OC(=O)N1CCC(N)CC1.CCOC(=O)COC(=O)Oc1ccccc1>>CCOC(=O)COC(=O)NC1CCN(C(=O)OC(C)(C)C)CC1,,Cc1ccccc1,,,,test
US20020107278A1,COc1ccccc1-c1cccc2[nH]c3c(c12)CCN(C(=O)c1ccccc1)CC3>>O=C(c1ccccc1)N1CCc2[nH]c3cccc(-c4ccccc4O)c3c2CC1,,ClCCl,,BrB(Br)Br,,test
US20080032967A1,C1COCCN1.O=C(Nc1ccc(OCCN2CCOCC2)c2ccccc12)c1ccnc(Cl)c1>>O=C(Nc1ccc(OCCN2CCOCC2)c2ccccc12)c1ccnc(N2CCOCC2)c1,,CCO,,,,test
US05834463,O=C1C2CCCC2=Nc2ccccc2N1Cc1cccc2ccccc12>>O=C1[C@H]2CCC[C@H]2Nc2ccccc2N1Cc1cccc2ccccc12,,CCCCCC,CCOC(C)=O,,,test
US20110015190A1,Fc1ccc(CBr)cc1.O=C1Nc2cccc(Br)c2C1=O>>O=C1C(=O)N(Cc2ccc(F)cc2)c2cccc(Br)c21,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20060058259A1,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)OCC(COC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)OC(=O)CCC(=O)O.Nc1nc2c(ncn2[C@H]2C[C@H](F)[C@@H](CO)O2)c(=O)[nH]1>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)OCC(COC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)OC(=O)CCC(=O)OC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)C[C@@H]1F,CN(C)c1ccncc1,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20110288066A1,C=Cc1ccc(S(C)(=O)=O)cc1[N+](=O)[O-]>>CCc1ccc(S(C)(=O)=O)cc1N,[Fe],CC(=O)O,,CCOC(C)=O,,test
US20050187220A1,CN(C)C1(c2ccccc2)CCC(O)CC1.Fc1cccc(CCl)c1>>CN(C)C1(c2ccccc2)CCC(OCc2ccc(F)cc2)CC1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20070149525A1,CC(C)(C)Cc1csc(C2(N)CC2)n1.CC(C)(C)OC(=O)NC(Cc1cc(F)cc(F)c1)C1CO1>>CC(C)(C)Cc1csc(C2(NC[C@@H](O)[C@H](Cc3cc(F)cc(F)c3)NC(=O)OC(C)(C)C)CC2)n1,,CC(C)O,,,,test
US04820834,CC(C)CC(NC(=O)OC(C)(C)C)C(=O)N1CC(CC2N=C(c3ccccc3)c3ccccc3NC2=O)c2ccccc21.Cl>>CC(C)CC(N)C(=O)N1CC(CC2N=C(c3ccccc3)c3ccccc3NC2=O)c2ccccc21.Cl,,CCOC(C)=O,,,,test
US20110053972A1,CC(C)(C)OC(=O)NCC(N)c1cccc2ccccc12.Cn1nccc1-c1cc(C(=O)O)cs1>>Cn1nccc1-c1cc(C(=O)NC(CNC(=O)OC(C)(C)C)c2cccc3ccccc23)cs1,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US04247715,CCOC(=O)COc1cc2c(c(Cl)c1Cl)C(=O)C(CC#C[Si](C)(C)C)(c1ccc(Cl)cc1)C2>>C#CCC1(c2ccc(Cl)cc2)Cc2cc(OCC(=O)O)c(Cl)c(Cl)c2C1=O,,CCO,,[Na+].[OH-],,test
US20080227784A1,COCCOCCl.O=C(O)c1cc(Cl)ccc1O>>COCCOCOc1ccc(Cl)cc1C(=O)O,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20090203703A1,CCOC(=O)c1sc2nc(CN3CCN(C(=O)OC(C)(C)C)CC3)[nH]c(=O)c2c1C>>Cc1c(C(=O)O)sc2nc(CN3CCN(C(=O)OC(C)(C)C)CC3)[nH]c(=O)c12,,[Na+],[OH-],Cl,,test
US20160068531A1,CCOC(=O)c1cc2cc(Cl)ccc2n1CCCSC>>CSCCCn1c(CO)cc2cc(Cl)ccc21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05114960,COC(=O)C1CCCCc2c(-c3ccc(Cl)cc3)noc2C1>>O=C(O)C1CCCCc2c(-c3ccc(Cl)cc3)noc2C1,,CO,,O,[K+].[OH-],test
US20110230537A1,CC(Cc1ccc(Cl)cc1Cl)=NO>>CC(Cc1ccc(Cl)cc1Cl)NO,,CC(=O)O,,[BH3-]C#N.[Na+],,test
US20160002188A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(-c3nc4ccccc4[nH]3)cc2)CC1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C(c1ccc(-c2nc3ccccc3[nH]2)cc1)N1CCNCC1,,ClCCl,,,,test
US20040122001A1,CS(=O)(=O)Cl.NC(=O)c1ccc2c(c1)CCOC2CCO>>CS(=O)(=O)OCCC1OCCc2cc(C(N)=O)ccc21,,C1CCOC1,CN(C)C=O,CCN(CC)CC,,test
US20070049603A1,CCOC(=O)c1sc2cnccc2c1Nc1ccc(Cl)cc1.N>>NC(=O)c1sc2cnccc2c1Nc1ccc(Cl)cc1,,CO,,,,test
US20150376225A1,CC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4CC5(CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C)OCCO5>>C[C@@H](O)[C@H]1CC[C@H]2[C@@H]3CC=C4CC5(CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C)OCCO5,,C1CCOC1,,[BH4-].[Na+],,test
US20080125468A1,CCCCCCC(COc1ccc(C(=O)NCCC(=O)OC(C)(C)C)cc1)c1ccc(Cl)nc1.OB(O)c1ccc(C(F)(F)F)cc1>>CCCCCCC(COc1ccc(C(=O)NCCC(=O)OC(C)(C)C)cc1)c1ccc(-c2ccc(C(F)(F)F)cc2)nc1,,Cc1ccccc1,,[F-].[K+],,test
US05576437,Cc1c(N=C=S)cc(C#N)c2cccnc12.NCCN>>Cc1c(NC(=S)NCCN)cc(C#N)c2cccnc12,,Cc1ccccc1,,,,test
US20150073019A1,COc1ccc2nc(N3N=C(c4cccc(C(F)(F)F)c4)C(=CN(C)C)C3=O)sc2c1>>COc1ccc2nc(N3N=C(c4cccc(C(F)(F)F)c4)C(=CN)C3=O)sc2c1,,CO,N,,,test
US20160009701A1,Cc1noc(C)c1-c1cc(C(N)=O)c2[nH]c3cc(C(C)(C)O)ccc3c2c1.O=S(=O)(Cl)C1CC1>>Cc1noc(C)c1-c1cc(C(N)=O)c2c(c1)c1ccc(C(C)(C)O)cc1n2S(=O)(=O)C1CC1,,CC#N,O,C,O=C[O-].[NH4+],test
US20100197619A1,C=O.COc1c(O)cc(O)c2c(=O)cc(-c3ccccc3)oc12.OCCNCCO>>COc1c(O)c(CN(CCO)CCO)c(O)c2c(=O)cc(-c3ccccc3)oc12,,CO,,,,test
US20110183947A1,N#Cc1ccco1.NO>>N=C(NO)c1ccco1,,CCO,,,,test
US05622983,C1CCOC1.CC(C)COC(=O)Cl.CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)O.NCCc1ccc2ccccc2n1>>CCCCCCCCC(C)OC(=O)NC(C)(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccc2ccccc2n1,,C1CCOC1,,CN1CCOCC1,,test
US20150126488A1,Clc1nc(Cl)c2cc[nH]c2n1.OCC1CCOC1>>Clc1nc(Cl)c2ccn(CC3CCOC3)c2n1,,ClCCl,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20050277661A1,O=C1c2ncc3c(ccn3Cc3ccc(F)cc3)c2CCCN1OC1CCCCO1>>O=C1c2ncc3c(ccn3Cc3ccc(F)cc3)c2CCCN1O,,CC(=O)O,,C1CCOC1,O,test
US20080293696A1,CC1(C)OCC(CNC(=O)c2cc(CNc3ccccc3C(=O)Nc3ccc4c(c3)OC(F)(F)O4)ccn2)O1>>O=C(NCC(O)CO)c1cc(CNc2ccccc2C(=O)Nc2ccc3c(c2)OC(F)(F)O3)ccn1,,CC(C)=O,,Cl,,test
US20140128429A1,CC(C)n1ccnc1.CC1(C)C(=O)N(Br)C(=O)N1Br>>CC(C)n1cncc1Br,,ClCCl,,O=S([O-])[O-].[Na+].[Na+],,test
US20080287409A1,COc1cc(OCc2sc(-c3ccc(C(F)(F)F)cc3)nc2CCCO)ccc1-c1noc(=O)[nH]1.CS(=O)(=O)OS(C)(=O)=O>>COc1cc(OCc2sc(-c3ccc(C(F)(F)F)cc3)nc2CCCOS(C)(=O)=O)ccc1-c1noc(=O)[nH]1,,ClCCl,,CCN(CC)CC,[Cl-].[NH4+],test
US20070299056A1,Ic1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1.O=C1CCCN1>>O=C1CCCN1c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1,[Cu],,,O=C([O-])[O-].[K+].[K+],,test
US20110288067A1,CCn1cc(-c2cnc3c(n2)c(C(=O)N[C@H](C)C(C)(C)O)cn3COCC[Si](C)(C)C)cn1>>CCn1cc(-c2cnc3[nH]cc(C(=O)N[C@H](C)C(C)(C)O)c3n2)cn1,,ClCCl,,NCCN,O=C(O)C(F)(F)F,test
US20080194816A1,Brc1ccccc1Br.C[SiH](C)Cl>>C[SiH](C)c1ccccc1Br,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US05025036,COC(=O)c1cccc(O)c1.ICCCCCCc1cccc(OCc2ccccc2)c1OCc1ccccc1>>COC(=O)c1cccc(OCCCCCCc2cccc(OCc3ccccc3)c2OCc2ccccc2)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140088075A1,CCn1c(=O)c(-c2cc(N)c(F)cc2Cl)cc2cnc(Cl)cc21.NC1CCOC1>>CCn1c(=O)c(-c2cc(N)c(F)cc2Cl)cc2cnc(NC3CCOC3)cc21,,CN1CCCC1=O,,C1CCC2=NCCCN2CC1,,test
US20110257210A1,COC(=O)c1ccc(Nc2ccc(F)c(Br)c2)c([N+](=O)[O-])c1>>COC(=O)c1ccc(Nc2ccc(F)c(Br)c2)c(N)c1,[Ni],CO,,NN,O,test
US20100210633A1,COc1cc(C=O)ccc1O.O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1(CC2CC2)CCNCC1>>COc1cc(CN2CCC(CC3CC3)(C(=O)NCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC2)ccc1O,,CCOC(C)=O,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070032515A1,CC1(C)OCc2cc(F)cc(OCc3ccccc3)c2O1>>OCc1cc(F)cc(OCc2ccccc2)c1O,,CCO,,Cl,,test
US20150094330A1,COC(=O)c1ccc(CCc2cccc3c2N(Cc2cccc(F)c2)CC3)cc1>>O=C(O)c1ccc(CCc2cccc3c2N(Cc2cccc(F)c2)CC3)cc1,,C1COCCO1,,Cl,[Li+].[OH-],test
US20050272763A1,CC(C)(C)C(=O)c1oc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc2c1N.O=C(Cl)CCCCl>>CC(C)(C)C(=O)c1oc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc2c1NC(=O)CCCCl,,ClCCl,,CCN(CC)CC,,test
US20150119404A1,CN1CCC(N)C1=O.N=C(c1ccccc1)c1ccccc1>>CN1CCC(N=C(c2ccccc2)c2ccccc2)C1=O,,ClCCCl,,,,test
US05210211,CCCc1nc(-n2c(C)ccc2C)c(CO)[nH]1>>CCCc1nc(-n2c(C)ccc2C)c(C=O)[nH]1,O=[Mn]=O,C1CCOC1,,,,test
US20090105257A1,O=C(O)[C@@H]1C[C@H]1c1ccc([N+](=O)[O-])cc1>>Nc1ccc([C@@H]2C[C@H]2C(=O)O)cc1,O=[Pt]=O,CO,,CCOC(C)=O,,test
US20110071150A1,COc1ccc(B(O)O)c(OC)c1.Fc1cccc(Cl)c1-c1cc2cc(Br)ccc2[nH]1>>COc1ccc(-c2ccc3[nH]c(-c4c(F)cccc4Cl)cc3c2)c(OC)c1,,C1COCCO1,,,,test
US04088775,C1=COCCC1.O=C1C[C@H]2[C@H](C[C@@H](O)[C@@H]2/C=C/C2(COc3ccc4ccccc4c3)OCCO2)O1>>O=C1C[C@H]2[C@H](C[C@@H](OC3CCCCO3)[C@@H]2/C=C/C2(COc3ccc4ccccc4c3)OCCO2)O1,,ClCCl,O,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20140274696A1,CCCC[Sn](C#C[Si](C)(C)C)(CCCC)CCCC.COC(=O)c1nc(-c2ccc(I)cc2)c(F)c(N)c1Cl>>COC(=O)c1nc(-c2ccc(C#C[Si](C)(C)C)cc2)c(F)c(N)c1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,,,test
US20140303127A1,CC(C)(C)[Si](OCc1ccc2[nH]c(=O)oc2c1)(c1ccccc1)c1ccccc1.OCCBr>>CC(C)(C)[Si](OCc1ccc2c(c1)oc(=O)n2CCO)(c1ccccc1)c1ccccc1,,CCOCC,CN(C)C=O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US05773428,CC(C)CC(CC(=O)NOCc1ccccc1)C(=O)N[C@H]1Cc2cn(c3ccccc23)CCCCCCCNC1=O>>CC(C)CC(CC(=O)NO)C(=O)N[C@H]1Cc2cn(c3ccccc23)CCCCCCCNC1=O,[Pd],C1CCOC1,CCO,[H][H],,test
US20050038072A1,O=C1CCNCC1C(c1ccc(F)cc1)c1ccc(F)cc1.O=[N+]([O-])c1ccc(O)c(CCl)c1>>O=C1CCN(Cc2cc([N+](=O)[O-])ccc2O)CC1C(c1ccc(F)cc1)c1ccc(F)cc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100075965A1,Cc1ccc(S(=O)(=O)Nc2ccc(Br)c(C)n2)cc1.NC(=O)CI>>Cc1ccc(S(=O)(=O)/N=c2/ccc(Br)c(C)n2CC(N)=O)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20110230485A1,O=[N+]([O-])c1c(Nc2ccc3[nH]ccc3c2)ncnc1-c1ccc(C(F)(F)F)cc1F>>Nc1c(Nc2ccc3[nH]ccc3c2)ncnc1-c1ccc(C(F)(F)F)cc1F,[Ni],CO,ClC(Cl)Cl,,,test
US20120309746A1,O=C1C[C@H]2CCC[C@]23OC[C@@H](c2ccccc2)N13>>OC[C@@H](c1ccccc1)N1CC[C@H]2CCC[C@H]21,,C1CCOC1,,,,test
US04931083,CCOC(=O)C(C)Oc1ncn(-c2ccc(Br)cc2)n1>>CC(Oc1ncn(-c2ccc(Br)cc2)n1)C(=O)O,,CCO,,[K+].[OH-],,test
US03932410,CCN1CCC(O)N(c2nnc(OC)s2)C1=O.CCO>>CCOC1CCN(CC)C(=O)N1c1nnc(OC)s1,,CCO,,Cc1ccccc1S(=O)(=O)O,,test
US20100210660A1,CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CO.COC(=O)c1ccc(Oc2ncc(O)cc2C)cc1>>COC(=O)c1ccc(Oc2ncc(OCc3c(-c4c(Cl)cccc4Cl)noc3C(C)C)cc2C)cc1,,c1ccccc1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110200586A1,CCOC(=O)C(F)(F)F.COC(=O)C1CC(N)CN1C(=O)OC(C)(C)C>>COC(=O)C1CC(NC(=O)C(F)(F)F)CN1C(=O)OC(C)(C)C,,CCOC(C)=O,CO,CCN(C(C)C)C(C)C,,test
US04276304,COc1ccc(C(O)C(C)(C)[N+](=O)[O-])c(OC)c1OC.O=S(Cl)Cl>>COc1ccc(C(Cl)C(C)(C)[N+](=O)[O-])c(OC)c1OC,,c1ccccc1,,,,test
US06054260,CCOC(=O)CN(C)c1ccc(N=O)cc1.S=C(n1ccnc1)n1ccnc1>>CCOC(=O)CN(C)c1ccc(N=C=S)cc1,[Pd],CCOC(C)=O,ClCCl,,,test
US20100278833A1,CS(=O)(=O)Cl.C[C@@H](Oc1cc(-n2cnc3cnc(CO)cc32)sc1C(N)=O)c1ccccc1F>>C[C@@H](Oc1cc(-n2cnc3cnc(COS(C)(=O)=O)cc32)sc1C(N)=O)c1ccccc1F,,ClCCl,,CCN(CC)CC,,test
US05608069,CC(C)CC=C(C=NO)c1ccccc1.CCOC(=O)[C@@H]1CCCN(CCBr)C1>>CCOC(=O)[C@@H]1CCCN(CCON=CC(=CCC(C)C)c2ccccc2)C1,,CC(C)=O,,Br,O=C([O-])[O-].[K+].[K+],test
US20120058976A1,CCCCCCCCCCCCCCCCOS(C)(=O)=O.CN1CCCC1=O>>CCCCCCCCCCCCCCCCOCCCO,,CN1CCCC1=O,,,,test
US20130123252A1,CC1(C)[C@@H]2CC[C@]13CS(=O)(=O)N1OC13C2.COC(=O)c1sc(C#CC(C)(C)C)cc1N1C(=O)CCC[C@H]1C1CCCCC1>>COC(=O)c1sc(C#CC(C)(C)C)cc1N1C(=O)[C@@H](O)CC[C@H]1C1CCCCC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20100068771A1,NC[C@@H](O)c1ccccc1Cl>>NC[C@H](O)c1ccccc1Cl,,CCO,,,,test
US20120028961A1,CS(=O)(=O)Cl.N#Cc1ccc(C(O)C2CCCCC2)cc1>>CS(=O)(=O)OC(c1ccc(C#N)cc1)C1CCCCC1,,ClCCl,O,CCN(CC)CC,O=C([O-])O.[Na+],test
US20030181449A1,COC(=O)c1ccc(-n2nc(O)c3[nH]c4cc(Cl)ccc4c(=O)c3c2=O)c(C)c1>>Cc1cc(C(=O)O)ccc1-n1nc(O)c2[nH]c3cc(Cl)ccc3c(=O)c2c1=O,,O,,Cl,[Na+].[OH-],test
US20160024097A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nn(C(=O)OC(C)(C)C)c2nc(-c3ccc(N)cc3)ncc12.N#Cc1ccc(Cl)cc1S(=O)(=O)Cl>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nn(C(=O)OC(C)(C)C)c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4C#N)cc3)ncc12,,ClCCl,c1ccncc1,,,test
US20090312381A1,COc1ccccc1C(=O)NNC(=O)NC1CC1>>COc1ccccc1-c1n[nH]c(=O)n1C1CC1,,[Na+],[OH-],Cl,,test
US04678502,CC(=O)OCCc1ccccc1S(=O)(=O)N=C=O.COc1cc(OC)nc(N)n1>>COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ccccc2CCOC(C)=O)n1,,CC#N,,,,test
US05883102,N.N#Cc1c(F)ccc(Cl)c1F>>N#Cc1c(F)ccc(Cl)c1N,,CC#N,,,,test
US06599917B1,C#CC1(O)CN2CCC1CC2.CC(O)CCc1cc(Cc2ccccc2)c(Br)cn1>>CC(O)CCc1cc(Cc2ccccc2)c(C#CC2(O)CN3CCC2CC3)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN1CCCC1=O,,CCN(CC)CC,,test
US20050234265A1,COc1cc(C(C)(C)C)ccc1CC(=O)O.ClCCl>>COc1cc(C(C)(C)C)ccc1CC(=O)Cl,,CCN(CC)CC,,,,test
US20030187026A1,Brc1cncc(Br)c1.Oc1cccc2cnccc12>>Brc1cncc(Oc2cccc3cnccc23)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05254548,CC(C)[C@H](N)C(=O)O.O=C(Cl)c1ccccc1>>CC(C)[C@H](NC(=O)c1ccccc1)C(=O)O,,O,,[Na+].[OH-],,test
US06121260,N=C(N)c1ccc(F)cc1.O=C(CBr)c1ccc(Cl)cc1>>Fc1ccc(-c2nc(-c3ccc(Cl)cc3)c[nH]2)cc1,,ClC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US20080085910A1,Cc1cc(C)nc(O)n1.O=P(Cl)(Cl)Cl>>Cc1cc(C)nc(Cl)n1,,O,,O=C([O-])O.[Na+],,test
US20110021529A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCCOCCOCCOCCOCCOCCO>>O=S(=O)(OCCOCCOCCOCCOCCOCCO)c1ccccc1,O=[Ag],ClCCl,,[I-].[K+],,test
US04439609,CN(C)Cc1ccnc(CO)c1.O=S(Cl)Cl>>CN(C)Cc1ccnc(CCl)c1.Cl,,ClCCl,,,,test
US20140179680A1,COC(=O)C1C(=O)C2C=CC1N2C(=O)OC(C)(C)C>>COC(=O)C1C(=O)C2CCC1N2C(=O)OC(C)(C)C,[Pd],CO,,,,test
US05298518,COc1nc2c(C)ccnc2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1>>Cc1ccnc2c1[nH]c(=O)n2Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,O,,Br,,test
US20130324579A1,Cc1cccc(-c2ocnc2C(=O)Nc2cnn(CCNC(=O)OC(C)(C)C)c2)c1>>Cc1cccc(-c2ocnc2C(=O)Nc2cnn(CCN)c2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04613676,CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)OC>>CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)OC,,O=C(O)C(F)(F)F,,,,test
US20090298807A1,CC(C)(C)OC(=O)N1CCC(O)(CC#N)CC1>>CC(C)(C)OC(=O)N1CCC(O)(CCN)CC1,O=[Pt]=O,CC(=O)O,CCO,[H][H],,test
US04544759,CI.NC(=S)c1ccc(Cl)cc1>>CSC(=N)c1ccc(Cl)cc1.I,,CC(C)=O,,,,test
US20020151547A1,Clc1ncccn1.O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CC[C@H](N2CCNCC2)[C@H](c2ccccc2)C1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CC[C@H](N2CCN(c3ncccn3)CC2)[C@H](c2ccccc2)C1,,ClCCl,,,,test
US20130296557A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.Cc1ccc(C(=O)O)cc1C#Cc1cnc2ccccc2c1>>Cc1ccc(C(O)=S)cc1C#Cc1cnc2ccccc2c1,,C1CCOC1,,,,test
US03991045,CCCCCCCCCCC(=O)OC(=O)CCCCCCCCCC.Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1>>CCCCCCCCCCC(=O)Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1,,O,,C1COCCO1,,test
US05932599,CC(=O)Nc1ccc(S(=O)(=O)Nc2cc(N)cc(N)c2)cc1>>Nc1ccc(S(=O)(=O)Nc2cc(N)cc(N)c2)cc1,,[Na+],[OH-],[Cl-].[NH4+],,test
US06300363B1,Nc1c(C(=O)c2ccccc2)[nH]c2cc(Cl)ccc12.O=C(Cl)c1ccccc1Cl>>O=C(Nc1c(C(=O)c2ccccc2)[nH]c2cc(Cl)ccc12)c1ccccc1Cl,,CCCCCC,ClCCl,,,test
US04451463,NC(=NCC(F)(F)F)Nc1ccnc(CCCOCc2ccccc2)n1>>NC(=NCC(F)(F)F)Nc1ccnc(CCCO)n1,[Pd],CCO,,Cl,,test
US20120258950A1,C1CNC1.CC(=O)O.CC(=O)O[BH-](OC(C)=O)OC(C)=O.CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3cccc(C=O)c3)c2)c2cncnc21.ClCCl.O>>CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3cccc(CN4CCC4)c3)c2)c2cncnc21.O=CO.O=C[O-],,ClCCl,O,Cl,,test
US20140057896A1,CC(C)(C)OC(=O)NCCn1ccc([N+](=O)[O-])n1.CI>>CN(CCn1ccc([N+](=O)[O-])n1)C(=O)OC(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20100298288A1,CC(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)N4CCC5(CCNCC5)C4)cc3)oc12.FC(F)(F)c1ccnc(Cl)n1>>CC(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)N4CCC5(CCN(c6nccc(C(F)(F)F)n6)CC5)C4)cc3)oc12,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20090124619A1,CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)NCC1CN(Cc2ccccc2)CCO1>>CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)NCC1CNCCO1,[Pd],CO,,N#N,,test
US05236902,O=C1c2ccccc2C(=O)N1CCSC[C@H]1O[C@@H](n2cnc3c(NCc4ccc([N+](=O)[O-])cc4)ncnc32)[C@H](O)[C@@H]1O>>NCCSC[C@H]1O[C@@H](n2cnc3c(NCc4ccc([N+](=O)[O-])cc4)ncnc32)[C@H](O)[C@@H]1O,,CCO,,NN,,test
US20130296355A1,COC(=O)C=CNC(=O)c1ccc(C(Oc2cc(C)c(-n3cc(C(F)(F)F)cn3)c(C)c2)C2CCC2)cc1.Cc1cc(OC(c2ccc(C(=O)NCCC(=O)O)cc2)C2CCC2)cc(C)c1-n1cc(C(F)(F)F)cn1>>Cc1cc(OC(c2ccc(C(=O)NC=CC(=O)O)cc2)C2CCC2)cc(C)c1-n1cc(C(F)(F)F)cn1.Cc1cc(OC(c2ccc(C(=O)NCCC(=O)O)cc2)C2CCC2)cc(C)c1-n1cc(C(F)(F)F)cn1,,C1CCOC1,,[Li+].[OH-],,test
US20050049286A1,CO.Cc1cc(C)c([N+](=O)[O-])c(C)c1Br>>COc1c(C)cc(C)c([N+](=O)[O-])c1C,,CO,c1ccncc1,C[O-].[Na+],,test
US20100249149A1,COc1ccccc1-c1cc(NC(=O)C2CCCNC2)ncn1.CS(=O)(=O)Cl>>COc1ccccc1-c1cc(NC(=O)C2CCCN(S(C)(=O)=O)C2)ncn1,,ClCCl,,CCN(CC)CC,,test
US20050148624A1,NCc1ccccc1.O=C(O)c1oc(=O)c2ccc(Br)cc2c1-c1ccccc1>>O=C(O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccccc1,,CO,,,,test
US20150299121A1,Cc1c([N+](=O)[O-])ccc(F)c1CN1CCN(C(=O)C2CCCC2)[C@@H](C)C1>>Cc1c(N)ccc(F)c1CN1CCN(C(=O)C2CCCC2)[C@@H](C)C1,[Pd],CCO,,,,test
US04337270,COc1cc(C(=O)Cl)cc(OC)c1OC.Nc1ccc(Cl)cc1C(=O)O>>COc1cc(C(=O)Nc2ccc(Cl)cc2C(=O)O)cc(OC)c1OC,,C1CCOC1,c1ccncc1,,,test
US20150166558A1,N#CCCCBr.N[C@@H](Cn1c(=O)c2c(n(Cc3c(F)cccc3C(F)(F)F)c1=O)COC21CCN(Cc2ccc(C(F)(F)F)o2)CC1)c1ccccc1>>N#CCCCN[C@@H](Cn1c(=O)c2c(n(Cc3c(F)cccc3C(F)(F)F)c1=O)COC21CCN(Cc2ccc(C(F)(F)F)o2)CC1)c1ccccc1,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US06602825B1,CC(=O)Nc1c(F)cc(Cl)cc1F.O=[N+]([O-])O>>CC(=O)Nc1c(F)cc(Cl)c([N+](=O)[O-])c1F,,O=S(=O)(O)O,,,,test
US20150284395A1,CCC(C=O)NC(=O)CCl>>CCc1coc(CCl)n1,,ClCCl,,O=P(Cl)(Cl)Cl,,test
US20140243336A1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1cnc(C#N)c(Nc2cccc(CN3CCN(C(=O)OC(C)(C)C)CC3)n2)c1>>N#Cc1ncc(N[C@@H]2CCCC[C@@H]2N)cc1Nc1cccc(CN2CCNCC2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080096922A1,COC(=O)C(c1cccc(OC)c1)C1CCNCC1.Clc1ncccn1>>COC(=O)C(c1cccc(OC)c1)C1CCN(c2ncccn2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160176816A1,CCOC(=O)c1ccccc1-c1ccc(F)cc1>>O=C(O)c1ccccc1-c1ccc(F)cc1,,CCO,,[Na+].[OH-],,test
US04260747,CCNCC.COC(C)(C)ON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CS[C@H]12)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>CCNCC.COC(C)(C)ON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CS[C@H]12)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,CCOC(C)=O,,CCOCC,,test
US20050197338A1,CI.NC(=O)Nc1cn(-c2ccc(-c3ccccc3O)c(F)c2)nc1C(N)=O>>COc1ccccc1-c1ccc(-n2cc(NC(N)=O)c(C(N)=O)n2)cc1F,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130330762A1,CCN(CC)c1ccc2cc(C=O)ccc2c1.O=S(=O)(c1ccccc1)N(F)S(=O)(=O)c1ccccc1>>CCN(CC)c1ccc2cc(C=O)ccc2c1F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04419352,CCCc1c(O)c(C(C)=O)cc2c(SCC)cc(C(=O)OC)nc12>>CCCc1c(O)c(C(C)=O)cc2ccc(C(=O)OC)nc12,[Ni],,,,,test
US20120094995A1,COC(=O)C12CCC(CC1)N2C(=O)OC(C)(C)C.[Li]c1ccccc1>>CC(C)(C)OC(=O)N1C2CCC1(C(=O)c1ccccc1)CC2,,C1CCOC1,,,,test
US20080139561A1,CC(C)Oc1cc(Nc2nc(F)c(C#N)cc2F)n[nH]1.C[C@H](N)c1ccc(F)cn1>>CC(C)Oc1cc(Nc2nc(N[C@@H](C)c3ccc(F)cn3)c(C#N)cc2F)n[nH]1,,CCCCO,O,CCN(C(C)C)C(C)C,,test
US20080076917A1,Brc1cn2cncc2s1.CN(C)C=O>>O=Cc1ncn2cc(Br)sc12,,ClCCl,O,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US20070249637A1,COC(=O)c1sccc1N.N#Cc1ncco1>>Oc1nc(-c2ncco2)nc2ccsc12,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20040043978A1,CCOC(=O)c1cn2c(n1)sc1cc(C)ccc12>>Cc1ccc2c(c1)sc1nc(C=O)cn12,,C1CCOC1,,CC(C)C[AlH]CC(C)C,,test
US20160024095A1,Cc1cnc(-c2cc(C3NCC4=CN(S(C)=O)CN=C4C3=O)ncc2Cl)c(C)c1.OC1CCNCC1>>Cc1cnc(-c2cc(C3NCC4=CN(N5CCC(O)CC5)CN=C4C3=O)ncc2Cl)c(C)c1,,CC(C)(C)O,,,,test
US20150252011A1,Brc1cnc2c(c1)CCC/C2=C\c1ccccc1.CO>>O=C1CCCc2cc(Br)cnc21,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100075965A1,Nc1ncc(Br)cc1S(=O)(=O)Cl.c1ccc(CC2CCNCC2)cc1>>Nc1ncc(Br)cc1S(=O)(=O)N1CCC(Cc2ccccc2)CC1,,CCOC(C)=O,c1ccncc1,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20110218200A1,O=C(Nc1cc([N+](=O)[O-])ccc1Br)c1ccccc1.O=C(c1ccccc1)N1CCNCC1>>O=C(Nc1cc([N+](=O)[O-])ccc1N1CCN(C(=O)c2ccccc2)CC1)c1ccccc1,,CN1CCCC1=O,,,,test
US05861510,COc1ccc(S(=O)(=O)N2CC=C[C@H](c3ccccc3)[C@@H]2C(=O)NOCc2ccccc2)cc1>>COc1ccc(S(=O)(=O)N2CCC[C@H](c3ccccc3)[C@@H]2C(=O)NO)cc1,[Pd],CCO,,,,test
US20050215792A1,CC(=O)c1cccc(C(C)=Nc2c(C)cc(C)cc2C)n1.CCCOc1c(-c2ccccc2)cc(N)cc1-c1ccccc1>>CCCOc1c(-c2ccccc2)cc(N=C(C)c2cccc(C(C)=Nc3c(C)cc(C)cc3C)n2)cc1-c1ccccc1,,Cc1ccccc1,,,,test
US20140213554A1,Cc1n[nH]cc1B1OC(C)(C)C(C)(C)O1.IC1COC1>>Cc1nn(C2COC2)cc1B1OC(C)(C)C(C)(C)O1,,CN(C)C=O,,[H-].[Na+],,test
US20150284380A1,Brc1nccs1.CCCC[Sn](CCCC)(CCCC)c1cncs1>>c1csc(-c2cncs2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,Cc1ccccc1,,,test
US20030144288A1,COc1ccc(C2=CCN(C(=O)OC(C)(C)C)CC2)c2sc(N)nc12.O=C(Cl)c1ccnc(Cl)c1>>COc1ccc(C2=CCN(C(=O)OC(C)(C)C)CC2)c2sc(NC(=O)c3ccnc(Cl)c3)nc12,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,CO,test
US20120010182A1,COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc(Oc3ccc(Br)cc3-c3ccnn3C)c(C#N)c2)c(OC)c1.COc1cccc(B(O)O)c1>>COc1cccc(-c2ccc(Oc3ccc(S(=O)(=O)Nc4nccs4)cc3C#N)c(-c3ccnn3C)c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,ClCCl,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20040058959A1,CN1CCCN(c2ccc(CN)cc2)CC1.O=C(Nc1ccc(Cl)cn1)c1cccnc1Cl>>CN1CCCN(c2ccc(CNc3ncccc3C(=O)Nc3ccc(Cl)cn3)cc2)CC1,,CS(C)=O,O,[Na+].[OH-],,test
US20150133457A1,COCCBr.O=[N+]([O-])c1cccc2[nH]ccc12>>COCCn1ccc2c([N+](=O)[O-])cccc21,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20050137184A1,O=C(O)/C=C/C(=O)O.c1cc2cc(-c3ccc(O[C@H]4CN5CCC4CC5)cc3)ccc2[nH]1>>O=C(O)/C=C/C(=O)O.c1cc2cc(-c3ccc(O[C@H]4CN5CCC4CC5)cc3)ccc2[nH]1,,CCO,CCOC(C)=O,,,test
US20120196851A1,CI.COC(=O)[C@@H]1CC[C@@H](Cn2c(=O)[nH]c3ccc(C(F)(F)F)cc32)CC1>>COC(=O)[C@@H]1CC[C@@H](Cn2c(=O)n(C)c3ccc(C(F)(F)F)cc32)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US04119710,CC(C)(C)N(Cc1ccccc1)CC(O)c1ccc(N)c(C(F)(F)F)c1>>CC(C)(C)NCC(O)c1ccc(N)c(C(F)(F)F)c1,[Pd],CO,Cl,[H][H],,test
US20030181519A1,O=C1CCC(=O)N1Cl.Oc1ccc2cc(Br)ccc2c1>>Oc1ccc2cc(Br)ccc2c1Cl,,C1CCOC1,,,,test
US06329392B1,COC(=O)c1ccc(Cn2c(C(=O)C3CCN(CCC4(c5ccccc5)CCN(C(=O)c5cc(OC)c(OC)c(OC)c5)C4)CC3)nc3ccccc32)cc1>>COc1cc(C(=O)N2CCC(CCN3CCC(C(=O)c4nc5ccccc5n4Cc4ccc(C(=O)O)cc4)CC3)(c3ccccc3)C2)cc(OC)c1OC,,O,,C1CCOC1,[Li+].[OH-],test
US20150361059A1,Cc1ccc([N+](=O)[O-])c(OC[C@H](NC(=O)OC(C)(C)C)C(=O)O)c1>>Cc1ccc(N)c(OC[C@H](NC(=O)OC(C)(C)C)C(=O)O)c1,[Pd],CO,,,,test
US20100010035A1,CCOCN(c1cc(C)on1)S(=O)(=O)c1cc(C)sc1Br.O=Cc1ccc(B(O)O)cc1>>CCOCN(c1cc(C)on1)S(=O)(=O)c1cc(C)sc1-c1ccc(C=O)cc1,,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20060094767A1,Cc1ccc(S(=O)(=O)OC[C@H]2CO2)cc1.O=[N+]([O-])c1c[nH]c(Cl)n1>>O=[N+]([O-])c1cn(C[C@@H]2CO2)c(Cl)n1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US03950427,CC(=O)/C=C/c1ccc(-c2ccccc2)c(Cl)c1>>CC(O)/C=C/c1ccc(-c2ccccc2)c(Cl)c1,,CCO,,[BH4-].[Na+],,test
US20080221136A1,CCOC(=O)c1[nH]ccc1N.O=Cc1cccc(=O)[nH]1>>CCOC(=O)c1[nH]ccc1NCc1cccc(=O)[nH]1,,CCO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20130336920A1,CC(C)(C)OC(=O)CCSCc1cccc(C(=O)O)c1.Nc1ccc(F)cc1-c1cc(C(=O)NCc2cccc(C(F)(F)F)c2)ccn1>>CC(C)(C)OC(=O)CCSCc1cccc(C(=O)Nc2ccc(F)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1,CN(C)c1ccncc1,CN(C)C=O,,CCN=C=NCCCN(C)C,Cl,test
US04267176,CCOC(=O)c1nccc(N)n1.O=CO>>CCOC(=O)c1nccc(NC=O)n1,,O=CO,,CC(=O)OC(C)=O,,test
US20100152168A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=c1[nH]c2cc(Cl)c(Cl)cc2[nH]1>>CC(C)(C)OC(=O)n1c(=O)n(C(=O)OC(C)(C)C)c2cc(Cl)c(Cl)cc21,CN(C)c1ccncc1,C1CCOC1,,,,test
US04248911,C1CO1.CC(=O)Nc1ccc(O)cc1.CC1CO1.O>>CC(O)CO.CC1CO1,,O,,,,test
US05300509,COc1ccc(CCNc2nc(Cl)c3nc(-c4ccco4)oc3n2)cc1.N>>COc1ccc(CCNc2nc(N)c3nc(-c4ccco4)oc3n2)cc1,,CCO,,O,[Cl-].[NH4+],test
US20030166579A1,COc1ccc2c(N)nc(C)cc2c1>>Cc1cc2cc(O)ccc2c(N)n1,,ClCCl,,BrB(Br)Br,,test
US05138069,CC(C)(C)[Si](C)(C)Cl.CCC=Cc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2C(=O)OC)cc1>>CCC=Cc1nc(Cl)c(CO[Si](C)(C)C(C)(C)C)n1Cc1ccc(-c2ccccc2C(=O)OC)cc1,,CN(C)C=O,,c1c[nH]cn1,,test
US04636521,BrP(Br)Br.CS(=O)(=O)NCc1ccc2[nH]cc(CCO)c2c1>>CS(=O)(=O)NCc1ccc2[nH]cc(CCBr)c2c1,,C1CCOC1,O,,,test
US20090018103A1,O=[N+]([O-])c1ccccc1Oc1ccccc1I>>Nc1ccccc1Oc1ccccc1I,,CCO,O,,,test
US20020022605A1,CCCCOc1ccc(S(=O)(=O)N2CCC(O)C2)cc1.CS(=O)(=O)Cl>>CCCCOc1ccc(S(=O)(=O)N2CCC(OS(C)(=O)=O)C2)cc1,,ClCCl,,CCN(CC)CC,,test
US20070054898A1,N#Cc1c(N2CCN(C(=O)c3cccs3)CC2)c2ccccc2[nH]c1=O.OB(O)c1ccccc1>>N#Cc1c(N2CCN(C(=O)c3cccs3)CC2)c2ccccc2n(-c2ccccc2)c1=O,,ClCCl,,CCN(CC)CC,,test
US20080114022A1,COC(=O)Cc1c(C)n(S(=O)(=O)c2ccc(C)c(Cl)c2)c2ncccc12>>Cc1ccc(S(=O)(=O)n2c(C)c(CC(=O)O)c3cccnc32)cc1Cl,,C1COCCO1,O,Cl,[Na+].[OH-],test
US20080171754A1,Brc1ccc2c(c1)CCNC2.Brc1cccc2c1CNCC2.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCc2cc(Br)ccc2C1.CC(C)(C)OC(=O)N1CCc2cccc(Br)c2C1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20080051404A1,CO[C@@H]1Cc2ccccc2[C@@H]1Nc1cc(N[C@H]2C[C@H](CO)[C@H](O[Si](C)(C)C(C)(C)C)C2)ncn1.NS(=O)(=O)Cl>>CO[C@@H]1Cc2ccccc2[C@@H]1Nc1cc(N[C@H]2C[C@H](COS(N)(=O)=O)[C@H](O)C2)ncn1,,CC#N,,c1ccncc1,,test
US05070089,COc1ccc(OC)c(CCl)c1.CSC(=S)N1CCNCC1>>COc1ccc(OC)c(CN2CCN(C(=S)SC)CC2)c1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20090111789A1,CNC1CCN(C(=O)OC(C)(C)C)CC1.CS(=O)(=O)Cl>>CN(C1CCNCC1)S(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20150225388A1,CC(C)CCCC(N)=S.O=C(CBr)c1ccc(C(=O)NCCC(F)(F)F)cc1>>CC(C)CCCc1nc(-c2ccc(C(=O)NCCC(F)(F)F)cc2)cs1,,C1CCOC1,,,,test
US20090111790A1,CC#N.Cn1ccc(NC(=O)c2cc(O)cc(OC3CCOCC3)c2)n1.O=C(c1ccc(Br)cn1)N1CCC1>>Cn1ccc(NC(=O)c2cc(OCc3ccccc3)cc(O[C@@H]3CCOC3)c2)n1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06107524,CCCCCCCCCO>>CCCCCCCCC=O,[Rh],,,,,test
US20040242573A1,BrCc1ccc(Br)cc1.FC1(F)CCNCC1>>FC1(F)CCN(Cc2ccc(Br)cc2)CC1,,CN(C)C=O,,,,test
US20070093521A1,CCOc1cc(C=O)cc(OCC)c1F.NC(=O)COc1ccc2oc(NC3CCNCC3)nc2c1>>CCOc1cc(CN2CCC(Nc3nc4cc(OCC(N)=O)ccc4o3)CC2)cc(OCC)c1F,,CC(=O)O,CCO,CCN(C(C)C)C(C)C,[BH3-]C#N.[Na+],test
US20020013328A1,CN(C)C=O.COc1cccc(Cc2nc3n(-c4c(Cl)cc(Br)cc4Cl)[nH]c(C(C)C)c-3c(=O)n2)c1>>COc1cccc(Cc2nc3n(-c4c(Cl)cc(C=O)cc4Cl)[nH]c(C(C)C)c-3c(=O)n2)c1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20080300232A1,O=C(CSc1cccc(Cl)c1)NC1CCN(Cc2ccccc2)CC1>>O=C(CSc1cccc(Cl)c1)NC1CCNCC1,,CC(Cl)Cl,,CC(Cl)OC(=O)Cl,,test
US20150246934A1,CC(C)(C)OC(=O)N1CC(C#N)C1.ClCCCBr>>CC(C)(C)OC(=O)N1CC(C#N)(CCCCl)C1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20130059853A1,CC(C)(CO)CBr.COc1c(OC(F)F)ccc(-c2ccc3c(c2)COC3=O)c1O>>COc1c(OC(F)F)ccc(-c2ccc3c(c2)COC3=O)c1OCC(C)(C)CO,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090286790A1,CCC1CC(N(Cc2cc(Cl)cc(C(F)(F)F)c2)c2ncc(O)cn2)CC(Cc2ccccc2)N1C(=O)OC(C)C.COCCBr>>CCC1CC(N(Cc2cc(Cl)cc(C(F)(F)F)c2)c2ncc(OCCOC)cn2)CC(Cc2ccccc2)N1C(=O)OC(C)C,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20040102324A1,Clc1cc[nH]n1.Clc1cccnc1Cl>>Clc1ccn(-c2ncccc2Cl)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090093444A1,CS(=O)(=O)c1ccc(-c2cn(CC(F)(F)F)nc2[C@@H]2CCC(F)(F)C[C@H]2CO)cc1.O=[Cr](=O)=O>>CS(=O)(=O)c1ccc(-c2cn(CC(F)(F)F)nc2[C@@H]2CCC(F)(F)C[C@H]2C(=O)O)cc1,,CC(C)=O,,O,O=S(=O)(O)O,test
US20020197333A1,O=C([O-])O.OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.[Na+]>>O=C([O-])O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO.[Na+],,O,,,,test
US20160244475A1,CCN(CC)S(F)(F)F.Cc1ncnc2c1ccn2[C@@H]1O[C@H]([C@@H](O)c2ccc(F)c(F)c2)[C@H]2OC(C)(C)O[C@H]21>>Cc1ncnc2c1ccn2[C@@H]1O[C@H](C(F)c2ccc(F)c(F)c2)[C@H]2OC(C)(C)O[C@H]21,,ClCCl,,,,test
US04672128,Cc1c[nH]c(C)n1.O=C=O>>Cc1nc(C(=O)O)c(C)[nH]1,,O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20060264460A1,N#Cc1cnc2c(Cl)cc(N)cc2c1Nc1ccc(F)c(Cl)c1.O=Cc1cc2n(n1)CCO2>>N#Cc1cnc2c(Cl)cc(NCc3cc4n(n3)CCO4)cc2c1Nc1ccc(F)c(Cl)c1,,CCO,,[BH3-]C#N.[Na+],,test
US20070197619A1,CN(CC#N)c1ccc(F)cc1.Nc1ccc(Cl)cc1>>CN(CC(=N)Nc1ccc(Cl)cc1)c1ccc(F)cc1,,Cc1ccccc1,,C[Al](C)C,,test
US05597845,C=CCN(C(=O)OC(C)(C)C)C(Cc1ccccc1)C(=O)O.CNCc1ccccc1>>C=CCN(C(=O)OC(C)(C)C)[C@@H](Cc1ccccc1)C(=O)N(C)Cc1ccccc1,,C1CCOC1,CCOC(C)=O,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20150119439A1,CC(C)(C)CC(=O)NC(=S)Nc1cc(-c2ccc(F)cc2)[nH]n1.CC(C)(C)N>>CC(C)(C)CC(=O)/N=C(\Nc1cc(-c2ccc(F)cc2)[nH]n1)NC(C)(C)C,,C1CCOC1,,CCN=C=NCCCN(C)C,,test
US20120083469A1,CON(C)C(=O)[C@@H]1CC[C@H](NC(=O)OCc2ccccc2)CC1.Clc1ccc(CBr)cc1>>CON(C)C(=O)[C@@H]1CC[C@H](N(Cc2ccc(Cl)cc2)C(=O)OCc2ccccc2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20070172385A1,CC(=O)O.CC1(C)OCc2cc([C@@H](O)CNCCCCCCOCCCCc3ccc4c(c3)S(=O)(=O)CCC4)ccc2O1>>O=COc1ccc([C@@H](O)CNCCCCCCOCCCCc2ccc3c(c2)S(=O)(=O)CCC3)cc1CO,,O,,,,test
US20160122345A1,CC[C@H]1c2ncc(C(=O)N[C@@H](CO)c3ccc(S(=O)(=O)CC)cc3)cc2CN1C(=O)OC(C)(C)C>>CC[C@@H]1NCc2cc(C(=O)N[C@@H](CO)c3ccc(S(=O)(=O)CC)cc3)cnc21,,ClCCl,,CCOC(C)=O,Cl,test
US20090215743A1,CCOC(=O)CC1OC(c2cccc(OC)c2OC)c2cc(Cl)ccc2-n2c(CC)nnc21>>CCc1nnc2n1-c1ccc(Cl)cc1C(c1cccc(OC)c1OC)OC2CC(=O)O,,C1COCCO1,,Cl,,test
US20160168156A1,CCOC=CC(=O)OCC.N#Cc1cn[nH]c1N>>N#Cc1cnn2ccc(=O)[nH]c12,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US03953492,CC(Cl)=NS(=O)(=O)c1cc(Br)c(N)c(Br)c1.CCNCC>>CCN(CC)C(C)=NS(=O)(=O)c1cc(Br)c(N)c(Br)c1,,ClCCl,,O,,test
US20030013713A1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CC(CO)=NC=C1OCc1ccccc1>>O=C1CC(COC(c2ccccc2)(c2ccccc2)c2ccccc2)=NC=C1OCc1ccccc1,CN(C)c1ccncc1,CN(C)C=O,,O,,test
US04230707,N#Cc1ccc2nc3cscc3c(=O)n2c1.[N-]=[N+]=[N-]>>O=c1c2cscc2nc2ccc(-c3nnn[nH]3)cn12,,CN(C)C=O,,[Cl-].[NH4+],,test
US20050032846A1,CCC(O)CC.Cc1cc(C)c(Oc2nc(C)nc(Cl)c2C)c(C)c1>>CCC(CC)Oc1nc(C)nc(Oc2c(C)cc(C)cc2C)c1C,,CS(C)=O,,[H-].[Na+],,test
US20060014803A1,CCOC(=O)c1ccc([Se]c2cc3c(cc2O)C(C)(C)CCC3(C)C)cc1.COC(=O)CCCCCCCBr>>CCOC(=O)c1ccc([Se]c2cc3c(cc2OCCCCCCCC(=O)OC)C(C)(C)CCC3(C)C)cc1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050209227A1,CC(C)(Cc1ccc(F)c(C(F)(F)F)c1)NC=O>>CC(C)(N)Cc1ccc(F)c(C(F)(F)F)c1,,O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20090181928A1,C=CC(=O)OC(C)(C)C.C[Si](C)(C)CCN1C(=O)CN(c2ccc(I)cc2OCc2ccccc2)S1(=O)=O>>CC(C)(C)OC(=O)/C=C/c1ccc(N2CC(=O)N(CC[Si](C)(C)C)S2(=O)=O)c(OCc2ccccc2)c1,,CC#N,,CCN(CC)CC,,test
US04826866,CCOC(=O)C(Cl)C(C)=O.Cl.NNC(=S)NC1CCCCC1>>CCOC(=O)c1c(NC2CCCCC2)n[nH]c1C.Cl,,CCO,,,,test
US20140171430A1,Cc1noc(-c2c(F)cccc2C(=O)N2CC3CN(C(=O)OC(C)(C)C)CC3C2)n1>>Cc1noc(-c2c(F)cccc2C(=O)N2CC3CNCC3C2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110136763A1,CCOC(=O)CC1OB(O)c2cc(O)cc(F)c21.Clc1cnccn1>>CCOC(=O)CC1OB(O)c2cc(Oc3cnccn3)cc(F)c21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140023611A1,CC(C)(C)OC(=O)CCSCc1cccc(C(=O)Nc2ccc(N3CCCC3)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1>>O=C(O)CCSCc1cccc(C(=O)Nc2ccc(N3CCCC3)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04648995,CC1=C2[C@@H]3CC[C@H]([C@H](C)CCC(=O)O)[C@@]3(C)[C@@H](O)C[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@H]2C1>>CC1=C[C@@H]2C[C@H](O)CC[C@]2(C)[C@H]2C[C@H](O)[C@]3(C)[C@@H]([C@H](C)CCC(=O)O)CC[C@H]3[C@H]12,,CCOC(C)=O,,,,test
US20070244331A1,CC(C)C(=O)O.CC(Cl)OC(=O)Sc1ccccc1>>CC(OC(=O)Sc1ccccc1)OC(=O)C(C)C,,CCOCC,,CCN(CC)CC,[I-].[Na+],test
US20130317001A1,C[C@@H]1CC[C@@H](COc2cc(F)c(C(=O)OC(C)(C)C)cc2C2CC2)CC1>>C[C@@H]1CC[C@@H](COc2cc(F)c(C(=O)O)cc2C2CC2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05891902,CC(=O)OC(c1ccccc1)c1ccccc1.CCOC(=O)c1cc2ccccc2[nH]1>>CCOC(=O)c1[nH]c2ccccc2c1C(c1ccccc1)c1ccccc1,,ClCCl,,O=C([O-])O.[Na+],,test
US20090318479A1,CC(C)OB(OC(C)C)OC(C)C.COc1ccc2ccoc2c1>>COc1ccc2cc(B(O)O)oc2c1,,C1CCOC1,,[Li]CCCC,,test
US20100298339A1,C1CCNC1.C=CC(=O)Nc1ccc(Br)cc1>>O=C(CCN1CCCC1)Nc1ccc(Br)cc1,,CCO,,,,test
US20160039838A1,C1CCC2SCCNC2C1.COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)/C=C/CBr>>COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)/C=C/CN1CCSC2CCCCC21,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,O,test
US06593314B1,C=CC[C@H]1CC(C(=O)OC)=C[C@H]2O[C@@H]12.[N-]=[N+]=[N-]>>C=CC[C@H]1CC(C(=O)OC)=C[C@H](N=[N+]=[N-])[C@H]1O,,CO,O,[Cl-].[NH4+],,test
US20120122863A1,COC(=O)[C@@H](C1CCCCC1)n1c(=O)[nH]c2ccccc2c1=O.Cc1cccc2c1c(C[N+](C)(C)C)cn2C>>COC(=O)[C@@H](C1CCCCC1)n1c(=O)c2ccccc2n(Cc2cn(C)c3cccc(C)c23)c1=O,,CCOC(C)=O,CN(C)C=O,[I-].[K+],,test
US20030225068A1,CSc1ccc2c(c1)CN(C(C)C)S(=O)(=O)N2.ClCCBr>>CSc1ccc2c(c1)CN(C(C)C)S(=O)(=O)N2CCCl,,CCCCCC,CN(C)C=O,[H][H],[H-].[Na+],test
US20100093757A1,CC(C)(C)[Si](OCCOC[C@H](Oc1ncnc2c1cnn2-c1ncccc1Cl)C(=O)Nc1ccc(C#N)cn1)(c1ccccc1)c1ccccc1>>N#Cc1ccc(NC(=O)[C@H](COCCO)Oc2ncnc3c2cnn3-c2ncccc2Cl)nc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130324506A1,CN1CCCC1=O.CO.CO[Na].c1ccc(-c2c[nH]cn2)cc1.c1ccccc1>>CC(C)(Cc1ccccc1)n1cnc(-c2ccccc2)c1,,CO,,,,test
US05192749,Cc1cn([C@@]2(C(=O)c3ccccc3)C[C@H](O[Si](C)(C)C(C)(C)C)C(CO)(CO)O2)c(=O)[nH]c1=O>>Cc1cn([C@@]2(C(=O)c3ccccc3)C[C@H](O)C(CO)(CO)O2)c(=O)[nH]c1=O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150218096A1,COC(=O)c1ccc(B(O)O)cc1.O=Cc1cccc2c1c(I)nn2C(=O)c1c(Cl)cccc1C(F)(F)F>>COC(=O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccc(C=O)c23)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20120258952A1,CCO/C=C\c1ccn2c(C(=O)Nc3cccc4c3c(CC)nn4Cc3cccc(C)n3)cnc2c1>>CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4cc(CC=O)ccn34)c12,O,C1COCCO1,,O=C([O-])O.[Na+],,test
US05319133,CCCCC(CC)CC(N)=O.OCl>>CCCCC(CC)CC(=O)NCl,,CCOC(C)=O,,,,test
US20040010009A1,CC(C)(C)OC(=O)N1CCC(O)CC1.Cc1cc([N+](=O)[O-])ccc1O>>Cc1cc([N+](=O)[O-])ccc1OC1CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040034015A1,CC(C)(C)OC(=O)N1CCc2[nH]c3c(N)cccc3c2C1.O=C(Cl)CCCl>>CC(C)(C)OC(=O)N1CCc2[nH]c3c(NC(=O)CCCl)cccc3c2C1,CN(C)c1ccncc1,c1ccccc1,,O=C([O-])O.[Na+],,test
US20060030600A1,Cc1cc(F)ccc1-c1cc(-c2ccncc2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1cc(F)ccc1-c1cc(C2CCNCC2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,O=[Pt]=O,CO,,O=S(=O)(O)O,,test
US05541197,CC(=O)c1cccnc1.Cl.O=C1CCC(=O)N1Cl>>Cl.O=C(CCl)c1cccnc1,,CCOCC,,,,test
US20040102494A1,O=C1CNCN1.O=[N+]([O-])c1ccccc1>>O=C1CN(c2ccc([N+](=O)[O-])cc2)CN1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20120208788A1,BrCc1ccccc1.Cc1c(C(F)(F)F)ccc(O)c1C(=O)Oc1ccccc1>>Cc1c(C(F)(F)F)ccc(OCc2ccccc2)c1C(=O)Oc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20050020684A1,CCOC(=O)/N=N/C(=O)OCC.CCOC(=O)[C@H](Cc1ccc(C#CCCCO)cc1)OC.Oc1ccc(-c2ccccc2)cc1>>CO[C@@H](Cc1ccc(C(=O)CCCCOc2ccc(-c3ccccc3)cc2)cc1)C(=O)O,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100029611A1,Nc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1.O=C1CC(C(=O)O)C1>>O=C(O)C1CC(Nc2ccc(-c3nc4ccc(C5(c6ccccc6)CC5)nc4s3)c(F)c2)C1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,CCN(CC)CC,,test
US20020103280A1,C1COCCO1.CC(C)CC(C)O.Cc1ccc(S(=O)(=O)O)cc1.O=C(O)CC(O)C(=O)O>>CC(C)CC(C)OC(=O)CC(O)C(=O)OC(C)CC(C)C,,C1COCCO1,,,,test
US20110076292A1,COC(=O)c1ccc2c(c1)OCCn1cc(C(N)=O)nc1-2.COC(OC)N(C)C.NNCC(F)(F)F>>COC(=O)c1ccc2c(c1)OCCn1cc(-c3ncnn3CC(F)(F)F)nc1-2,,CC(=O)O,,Cl,,test
US20060270686A1,COc1ccc(COc2cc(Br)cc(Nc3cccnc3)c2)cc1.N#Cc1ccc2[nH]ccc2c1>>N#Cc1ccc2c(ccn2-c2cc(O)cc(Nc3cccnc3)c2)c1,[Cu]I,Cc1ccccc1,,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20080081822A1,BrCC1CCCCO1.CC(=O)SC(C)(C)C(=O)Nc1cc(C(C)(C)C)on1>>CC(C)(SCC1CCCCO1)C(=O)Nc1cc(C(C)(C)C)on1,,CCO,,C[O-].[Na+],,test
US20120232051A1,CC1CCCCN1c1ccncc1N(C)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.COc1cnccc1B(O)O>>CNc1cnccc1-c1ccncc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020103229A1,COc1ccc(-c2n[nH]c3ccc(C#N)cc23)cc1OC.OO>>COc1ccc(-c2n[nH]c3ccc(C(N)=O)cc23)cc1OC,,CCO,O,Cl,[Na+].[OH-],test
US20100210466A1,CC(=O)OO.CCc1ccc(-c2ccc(Cl)cc2Cl)cc1C1C(=O)C(C)(C)SC(C)(C)C1=O>>CCc1ccc(-c2ccc(Cl)cc2Cl)cc1C1C(=O)C(C)(C)S(=O)C(C)(C)C1=O,,ClCCl,,,,test
US20100029633A1,COCCOc1ccn2c(-c3ccc4cccc(OCC5(F)CCN(C(=O)OC(C)(C)C)CC5)c4n3)cnc2c1>>COCCOc1ccn2c(-c3ccc4cccc(OCC5(F)CCNCC5)c4n3)cnc2c1,,C1COCCO1,,Cl,,test
US20100173933A1,N=C(NO)c1nccs1.O=C(Cl)CCl>>ClCc1nc(-c2nccs2)no1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20140024644A1,Brc1cn[nH]c1.FCCBr>>FCCn1cc(Br)cn1,,CN(C)C=O,,[H-].[Na+],,test
US20100075976A1,CN(CCN1CCN(c2nccnc2Cl)CC1)S(=O)(=O)c1ccccc1.OCc1ccc(B(O)O)cc1>>CN(CCN1CCN(c2nccnc2-c2ccc(CO)cc2)CC1)S(=O)(=O)c1ccccc1.Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(=O)N(C)C,,O,O=C([O-])[O-].[K+].[K+],test
US20030134867A1,CN(C)C1Cn2c(-c3ccnc(S(C)(=O)=O)n3)c(-c3ccc(F)cc3)c(=O)n2C1.C[C@H](N)c1ccccc1>>C[C@H](Nc1nccc(-c2c(-c3ccc(F)cc3)c(=O)n3n2CC(N(C)C)C3)n1)c1ccccc1,,Cc1ccccc1,,,,test
US04070176,COc1ccc(S(=O)(=O)Cl)cc1.O=C(O)CNCC(=O)O>>COc1ccc(S(=O)(=O)N(CC(=O)O)CC(=O)O)cc1,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20130225524A1,Cc1noc(C)c1-c1ccc2c(Cl)c(C(N)=O)cnc2c1.Nc1cc(C(=O)O)cc([N+](=O)[O-])c1>>Cc1noc(C)c1-c1ccc2c(Nc3cc(C(=O)O)cc([N+](=O)[O-])c3)c(C(N)=O)cnc2c1,,CC(=O)O,,,,test
US05679282,CCCCCC[C@H](C)O.CCC[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](c3cc(F)c(O)c(F)c3)CC2)CC1>>CCCCCC[C@@H](C)Oc1c(F)cc([C@@H]2CC[C@@H]([C@@H]3CC[C@@H](CCC)CC3)CC2)cc1F,,C1CCOC1,ClCCl,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080261977A1,COC(=O)c1cnc(Nc2cccc(Cl)c2)nc1C(F)(F)F>>O=C(O)c1cnc(Nc2cccc(Cl)c2)nc1C(F)(F)F,,CO,,[K+].[OH-],,test
US20040058907A1,CC(C)(C)OC(=O)NCCCBr.CCS>>CCSCCCNC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150366977A1,CC(=O)c1ccccc1OCC(=O)O>>Cc1coc2ccccc12,,CC(=O)OC(C)=O,,CC(=O)[O-].[Na+],,test
US04711889,CCN(CC)CCn1c2ccccc2c(=O)c2ccccc21.O=C(Cl)C(=O)Cl>>CCN(CC)CC[n+]1c2ccccc2c(Cl)c2ccccc21.[Cl-],,ClCCl,,,,test
US05525711,Nc1nc(N)c(N=O)c(OCc2ccccc2)n1>>Nc1nc(N)c(N)c(OCc2ccccc2)n1,,O,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20110237573A1,Cc1cc(B(O)O)ccn1.Cc1cc(N)c(F)cc1Br>>Cc1cc(-c2cc(F)c(N)cc2C)ccn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20070043048A1,CSc1nccc(-c2ccc(Br)cc2)n1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1nccc(-c2ccc(Br)cc2)n1,,ClCCl,,,,test
US20120329791A1,CC(C)(C)OC(=O)NC1(c2ccc(-n3c(-c4cccnc4N)nc4ccc(Cl)nc43)cc2)CCC1.CC1(C)OB(c2cccc(NC(=O)C3CCOCC3)c2)OC1(C)C>>CC(C)(C)OC(=O)NC1(c2ccc(-n3c(-c4cccnc4N)nc4ccc(-c5cccc(NC(=O)C6CCOCC6)c5)nc43)cc2)CCC1,,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20070244133A1,COC(=O)Cl.CSc1ncnc2sccc12>>COC(=O)c1cc2c(SC)ncnc2s1,,C1CCOC1,,[Li]CCCC,,test
US20070032494A1,CC(=O)OCCc1cc(Br)c(Oc2ccc(=O)n(C(C)C)n2)c(Br)c1>>CC(C)n1nc(Oc2c(Br)cc(CCO)cc2Br)ccc1=O,,CO,,[K+].[OH-],,test
US20090209522A1,COc1nc(N2CCN(C(=O)OC(C)(C)C)CC2)nc(OC)c1[N+](=O)[O-]>>COc1nc(N2CCN(C(=O)OC(C)(C)C)CC2)nc(OC)c1N,,CCO,,,,test
US20140046069A1,BrBr.Cc1cccc(N2CCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)n1>>Cc1nc(N2CCC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)ccc1Br,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20070219210A1,COc1ccc(C(=O)N(C)OC)cn1.[Li]C>>COc1ccc(C(C)=O)cn1,,C1CCOC1,CCOC(C)=O,O,[Cl-].[NH4+],test
US05292627,CCCCCCSCCSCCSc1nc(N)n[nH]1.CCOC(=O)CC(C)=O>>CCCCCCSCCSCCSc1nc2nc(C)cc(O)n2n1,,CC(=O)O,,,,test
US20070032485A1,CCOC(=O)N1c2ccc(OC)nc2[C@@H](Nc2ncc(C(=O)O)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC>>CCOC(=O)N1c2ccc(OC)nc2[C@@H](Nc2ncc(CO)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US20150057265A1,C[C@@H]1C[C@H](NC(=O)OC(C)(C)C)CN(c2ccncc2N)C1.Cc1cnc2c(C(=O)O)c(NC(=O)OC(C)(C)C)oc2c1>>Cc1cnc2c(C(=O)Nc3cnccc3N3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](C)C3)c(NC(=O)OC(C)(C)C)oc2c1,,ClCCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05643893,Cc1c[nH]c(=O)[nH]c1=O.OB(O)CCCCBr>>Cc1cn(CCCCB(O)O)c(=O)[nH]c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060094843A1,CCCCCBr.CCOC(=O)C1CCCC1=O>>CCCCCC1(C(=O)OCC)CCCC1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040229876A1,COc1cc2nccc(Oc3ccc(N)c(Cl)c3)c2cc1OC.Cc1csc(N)n1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4nc(C)cs4)c(Cl)c3)c2cc1OC,,ClC(Cl)Cl,O,c1ccncc1,,test
US20080009530A1,CC(C)OCCNS(=O)(=O)NC(=O)OCCCc1ccc(OCCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1Oc1ncc(C(F)(F)F)cc1Cl>>CC(C)OCCNS(=O)(=O)NC(=O)OCCCc1ccc(OCCO)cc1Oc1ncc(C(F)(F)F)cc1Cl,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20040006143A1,COC(=O)c1ccc(-c2ccc(CCN)cc2)cc1.O=Cc1ccccc1>>COC(=O)c1ccc(-c2ccc(CCNCc3ccccc3)cc2)cc1,,ClCCl,,Cl,,test
US20040266782A1,CC(C)C(N)c1ccnc(Cc2ccc(Cl)c(Cl)c2)c1.COc1cccc(N=C=O)c1>>COc1cccc(NC(N)=O)c1,,CCOC(C)=O,ClCCl,,,test
US20120071478A1,C[C@@H](N)c1ccccc1.Clc1cnc2cc(Br)ccc2n1>>C[C@@H](Nc1cnc2cc(Br)ccc2n1)c1ccccc1,,CS(C)=O,,O,,test
US20050075378A1,CCOP(=O)(CC(C)=NNS(=O)(=O)c1ccc(C)cc1)OCC.O=Cc1ccc(-c2ccccc2)cc1>>Cc1cc(-c2ccc(-c3ccccc3)cc2)[nH]n1,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20120270938A1,COCOc1c(C)cc(/C=C/c2cccc(C(=O)O)c2)cc1C.Sc1ccccc1>>COCOc1c(C)cc(/C=C/c2cccc(C(=O)Sc3ccccc3)c2)cc1C,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20100152190A1,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.CC1(N)CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2(C)CCN(C(=O)OC(C)(C)C)CC2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F,,ClCCl,ClCCl,CCN(C(C)C)C(C)C,,test
US20150038438A1,CC1=CCCC(=O)c2cc3cc(CO[Si](C)(C)C(C)(C)C)n(C)c3cc21>>CC1CCCC(=O)c2cc3cc(CO[Si](C)(C)C(C)(C)C)n(C)c3cc21,[Pd],CCOC(C)=O,ClCCl,,,test
US05439925,C=CCO.CCOC(=O)c1ccc(N)cc1>>C=CCOC(=O)c1ccc(N)cc1,,CCCCCC,,[Na],,test
US20090298826A1,COc1cc(O)ccc1-c1ccc2c(c1COC(=O)c1ccc(C)s1)C(C)=CC(C)(C)N2.O=S(=O)(Cl)CCC(F)(F)F>>COc1cc(OS(=O)(=O)CCC(F)(F)F)ccc1-c1ccc2c(c1COC(=O)c1ccc(C)s1)C(C)=CC(C)(C)N2,,ClCCl,,CCN(CC)CC,,test
US20070213339A1,CCOC=C(C(=O)OCC)C(=O)c1cc(F)c(F)c(OC(F)(F)Cl)c1F.Nc1ccc(CN2CCCC2)cc1>>CCOC(=O)/C(=C\Nc1ccc(CN2CCCC2)cc1)C(=O)c1cc(F)c(F)c(OC(F)(F)Cl)c1F,,CCO,,,,test
US20140309210A1,BrCc1cccc(Br)c1.C[Si](C)(C)CCOCn1nc(C(=O)Nc2cn[nH]c2)c2ccc(-c3cnn(C4CCCCO4)c3)cc21>>C[Si](C)(C)CCOCn1nc(C(=O)Nc2cnn(Cc3cccc(Br)c3)c2)c2ccc(-c3cnn(C4CCCCO4)c3)cc21,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050020623A1,CC(C)(CNC(=O)OC(C)(C)C)CNS(=O)(=O)c1cccc2cnccc12>>CC(C)(CN)CNS(=O)(=O)c1cccc2cnccc12,,CO,,Cl,,test
US20140113898A1,N#Cc1ccc(S(=O)(=O)c2cccc(C(F)(F)F)c2)cc1>>NCc1ccc(S(=O)(=O)c2cccc(C(F)(F)F)c2)cc1,,CO,,N,,test
US20080249093A1,COC(=O)CC1CCc2cc(O)c(C)cc21.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)CC1CCc2cc(OS(=O)(=O)C(F)(F)F)c(C)cc21,,ClCCl,,c1ccncc1,,test
US05089504,CCC(=O)C(=CNc1ccccc1OC)C(=O)OC>>CCC(=O)c1c[nH]c2c(OC)cccc2c1=O,,c1ccc(Oc2ccccc2)cc1,,,,test
US20160031871A1,O=C1CN(c2ncc(CO)s2)CCN1.O=S(Cl)Cl>>O=C1CN(c2ncc(CCl)s2)CCN1,,ClCCl,,,,test
US20110263598A1,C1COCCN1.CC1(C)OB(/C=C/c2ccc(C=O)c(F)c2)OC1(C)C>>CC1(C)OB(/C=C/c2ccc(CN3CCOCC3)c(F)c2)OC1(C)C,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160185780A1,CN1CCC(N(C)C(=O)c2ccc(Nc3nc4c(Br)cccn4n3)cc2)CC1.CSc1ccc(C2(CO)CCNCC2)cc1>>CSc1ccc(C2(CO)CCN(c3cccn4nc(Nc5ccc(C(=O)N(C)C6CCN(C)CC6)cc5)nc34)CC2)cc1,,CC#N,,O,,test
US20150329533A1,CCOC(=O)c1cc(CC(C)C)n(-c2ccc(F)cc2)n1>>CC(C)Cc1cc(C=O)nn1-c1ccc(F)cc1,,ClCCl,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20100286120A1,O=C1c2ccc(F)nc2OCCN1Cc1ccccc1.Oc1cccc(Cl)c1>>O=C1c2ccc(Oc3cccc(Cl)c3)nc2OCCN1Cc1ccccc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140275172A1,COC(Cl)Cl.COc1ccc(OC(F)(F)F)cc1.O>>COc1ccc(OC(F)(F)F)cc1C=O,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US06187805B1,CCOC(=O)C=Cc1cccc2c1ccn2S(=O)(=O)c1ccccc1>>CCOC(=O)CCc1cccc2c1ccn2S(=O)(=O)c1ccccc1,[Pd],CCO,CCOC(C)=O,,,test
US20150315198A1,Clc1ncnc2[nH]ncc12.OCC1CCC(Cn2cccn2)CC1>>Clc1ncnc2nn(CC3CCC(Cn4cccn4)CC3)cc12,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05872136,Cl.Clc1nc(CBr)ccc1-c1ccccc1.N#Cc1ccc(Cc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)cc1>>Cl.N#Cc1ccc(Cc2cncn2Cc2ccc(-c3ccccc3)c(Cl)n2)cc1,,CC#N,CO,,,test
US20110166123A1,CO.O=C(O)c1ccc(Cl)nc1Cl>>COc1ccc(C(=O)O)c(Cl)n1,,CO,,CC(C)(C)[O-].[K+],,test
US06413938B1,CC(C)N.C[C@H]1O[C@@H](n2c(Br)nc3cc(Cl)c(Cl)cc32)[C@H](O)[C@@H]1O>>CC(C)Nc1nc2cc(Cl)c(Cl)cc2n1[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O,,ClCCl,,,,test
US20100113454A1,NC(=O)c1cccn1N.O=C(O)[C@H]1CCCN1C(=O)OCc1ccccc1>>NC(=O)c1cccn1NC(=O)[C@H]1CCCN1C(=O)OCc1ccccc1,,C1CCOC1,,CCN=C=NCCCN(C)C,Cl,test
US05672597,CCOC(=O)NCCSCC(=O)O.NCCCOc1cccc(CN2CCCCC2)c1>>CCOC(=O)NCCSCC(=O)NCCCOc1cccc(CN2CCCCC2)c1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US06548494B1,O=Cc1ccc2c3c1ccn3C(=O)CNC2>>O=C1CNCc2ccc(CO)c3ccn1c23,,CCO,,[BH4-].[Na+],,test
US05550134,CN1C(=O)CC[C@]2(C)c3ccc(S)cc3CC[C@@H]12.Fc1cccc2sc(Cl)nc12>>CN1C(=O)CC[C@]2(C)c3ccc(Sc4nc5c(F)cccc5s4)cc3CC[C@@H]12,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20120101134A1,CCOC(=O)CCCc1cccc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)c1C(F)(F)F>>CC(C)Oc1ccc(-c2nc(-c3cccc(CCCC(=O)O)c3C(F)(F)F)no2)cc1C#N,,CC(C)O,O,Cl,[Na+].[OH-],test
US04935432,O=C1c2ccccc2C(=O)N1CCBr.c1ccc2c(C3CCNCC3)c[nH]c2c1>>O=C1c2ccccc2C(=O)N1CCN1CCC(c2c[nH]c3ccccc23)CC1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20150307449A1,CN(C)C(=O)COc1cccc(S(=O)(=O)n2cc(CN(C)C(=O)OC(C)(C)C)cc2C2=CCCCC2)c1>>CNCc1cc(C2=CCCCC2)n(S(=O)(=O)c2cccc(OCC(=O)N(C)C)c2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040198784A1,CSc1csc(S(N)(=O)=O)c1.O=C1CCC(=O)N1Br>>CSc1cc(S(N)(=O)=O)sc1Br,,CC(=O)O,ClC(Cl)Cl,[Na+].[OH-],,test
US20120040948A1,CC(CCl)CBr.Cn1cnc(S(=O)(=O)NCCOc2cc3c(cc2F)CC(N)C3Cc2ccccc2)c1>>CC1CN(C2Cc3cc(F)c(OCCNS(=O)(=O)c4cn(C)cn4)cc3C2Cc2ccccc2)C1,O,ClCCl,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20090186895A1,CC(C)(COS(C)(=O)=O)[N+](=O)[O-].Cn1ncc(Cl)c1-c1cc(NC(=O)c2cccc(C(F)(F)F)c2)ccc1O>>Cn1ncc(Cl)c1-c1cc(NC(=O)c2cccc(C(F)(F)F)c2)ccc1OCC(C)(C)[N+](=O)[O-],,CC(=O)N(C)C,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20070219374A1,CNc1ccccc1.O=C1CCC(=O)CC1>>CN(c1ccccc1)c1ccc(O)cc1,,CCO,,CCN(CC)CC,,test
US20040082607A1,CC(C)Cn1c(CNC(=O)OC(C)(C)C)c(-c2ccccc2)c2cc(-c3nsc(=O)[nH]3)ccc2c1=O.Cl>>CC(C)Cn1c(CN)c(-c2ccccc2)c2cc(-c3nsc(=O)[nH]3)ccc2c1=O.Cl,,C1CCOC1,CCOC(C)=O,,,test
US05686486,CCC(O)c1cccc2ccccc12.O=c1cc(O)c2ccccc2o1>>CCC(c1c(O)c2ccccc2oc1=O)c1cccc2ccccc12,,C1COCCO1,,CCOCC,FB(F)F,test
US20100227864A1,CCOC(=O)c1ccc(-n2cc(C#N)c(-c3cccc(COCc4ccccc4)c3)c2)cc1>>CCOC(=O)c1ccc(-n2cc(C#N)c(-c3cccc(CO)c3)c2)cc1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20100168080A1,COC(=O)c1cc(Cl)ccc1OCCCN1CCC(O)(Cc2ccc(Cl)cc2)C(C)(C)C1>>CC1(C)CN(CCCOc2ccc(Cl)cc2C(=O)O)CCC1(O)Cc1ccc(Cl)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20090291917A1,CC(C)(C)[Si](C)(C)Oc1ccc(Br)c(CO)c1.COCCl>>COCOCc1cc(O[Si](C)(C)C(C)(C)C)ccc1Br,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US06541647B2,C#C[C@H](CC[C@H](O)CO)OC(C)=O.Cc1ccc(S(=O)(=O)Cl)cc1>>C#C[C@H](CC[C@H](O)COS(=O)(=O)c1ccc(C)cc1)OC(C)=O,,ClCCl,,c1ccncc1,,test
US05527816,BrCBr.N#CC(CCOc1ccccc1)c1ccc(Cl)cc1>>N#CC(CBr)(CCOc1ccccc1)c1ccc(Cl)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20090030195A1,NCCO.O=C(CCl)Nc1ccc2cc(-c3ccccc3C(F)(F)F)[nH]c(=O)c2c1>>O=C(CNCCO)Nc1ccc2cc(-c3ccccc3C(F)(F)F)[nH]c(=O)c2c1,,O,,CCN(CC)CC,CCO,test
US20110082173A1,CCN(CC)C(=O)c1ccc(C(Br)=C2CCN(C(=O)OC(C)(C)C)CC2)cc1.O=[N+]([O-])c1ccccc1B(O)O>>CCN(CC)C(=O)c1ccc(C(=C2CCNCC2)c2ccccc2[N+](=O)[O-])cc1,,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US05994368,COCOc1ccc(Cl)c(COS(C)(=O)=O)c1Cl.Cc1ccc2cccc(O)c2n1>>COCOc1ccc(Cl)c(COc2cccc3ccc(C)nc23)c1Cl,,CN(C)C=O,,O,[H-].[Na+],test
US05596104,CN.O=C(O)c1c(Cl)cc(Cl)c(Cl)c1C(=O)O>>CN1C(=O)c2c(Cl)cc(Cl)c(Cl)c2C1=O,,CC(=O)O,,,,test
US06150351,CC(C)(C)C(=O)OCI.Cc1nnc(C2=C(C(O)=S)N3C(=O)[C@@H](NC(=O)Cc4ccccc4)[C@H]3SC2)s1>>Cc1nnc(C2=C(C(=S)OCOC(=O)C(C)(C)C)N3C(=O)[C@@H](NC(=O)Cc4ccccc4)[C@H]3SC2)s1,,CC(=O)N(C)C,CCOC(C)=O,O,O=C([O-])[O-].[Cs+].[Cs+],test
US04631274,COC(=O)CON=C(C(=O)CCl)C(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(/C=C/Cl)CS[C@H]12.NC(N)=S>>COC(=O)CON=C(C(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(/C=C/Cl)CS[C@H]12)c1csc(N)n1,,C1CCOC1,O,CC(=O)[O-].[Na+],,test
US20060166997A1,COC(=O)C(O)c1cc(OC)c(OC)cc1F.CS(=O)(=O)Cl>>COC(=O)C(Cl)c1cc(OC)c(OC)cc1F,,ClCCl,,CCN(CC)CC,,test
US20100204196A1,COc1cc(OCCN2CCN(C)CC2)ccc1[N+](=O)[O-]>>COc1cc(OCCN2CCN(C)CC2)ccc1N,[Pd],CO,,,,test
US20110245249A1,FC(F)(F)c1cnc(Cl)nc1Cl.NC1CCC1>>FC(F)(F)c1cnc(Cl)nc1NC1CCC1,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US20140275241A1,CC(=O)OC(C)=O.C[C@@]12CC[C@H]3C[C@H]4C[C@H](O)CC[C@@H]4C[C@@H]3[C@H]1C/C(=C\c1ccccc1)[C@H]2O>>CC(=O)O[C@@H]1CC[C@@H]2C[C@H]3[C@@H](CC[C@@]4(C)[C@H](OC(C)=O)/C(=C/c5ccccc5)C[C@H]34)C[C@H]2C1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US20120238574A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc([N+](=O)[O-])cc2)C1>>O=[N+]([O-])c1ccc(OC2CCNC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140371278A1,C=CCC1(S(=O)(=O)Cl)CC1.O=c1[nH]c2cc3ocnc3c(F)c2n1-c1ccc(Br)cc1Cl>>C=CCC1(S(=O)(=O)n2c(=O)n(-c3ccc(Br)cc3Cl)c3c(F)c4ncoc4cc32)CC1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US03954752,C[Si](C)(C)Cl.C[Si](C)(C)N[Si](C)(C)C.O=c1cn[nH]c(=O)[nH]1>>C[Si](C)(C)Oc1cnnc(O[Si](C)(C)C)n1,,c1ccccc1,,CCN(CC)CC,,test
US20030055047A1,COc1cc(C=O)ccc1OS(=O)(=O)C(F)(F)F.OB(O)c1ccccc1C(F)(F)F>>COc1cc(C=O)ccc1-c1ccccc1C(F)(F)F,,CN(C)C=O,,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20100286126A1,CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccc(O)cc4)c4ccc(O)cc4)nc(N4CC[C@@H](NC(=O)OC(C)(C)C)C4)nc32)[C@H](O)[C@@H]1O>>CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccc(O)cc4)c4ccc(O)cc4)nc(N4CC[C@@H](N)C4)nc32)[C@H](O)[C@@H]1O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110287353A1,COc1ccc(-c2ccc(N(c3ccc(-c4ccc(OC)cc4)cc3)c3ccc(-c4ccc(N(c5ccc(C)cc5)c5ccc(C)cc5)cc4)cc3)cc2)cc1>>Cc1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccc(N(c4ccc(-c5ccc(O)cc5)cc4)c4ccc(-c5ccc(O)cc5)cc4)cc3)cc2)cc1,,ClCCl,,BrB(Br)Br,,test
US20070135385A1,BrCc1ccccc1.CCOC(C)=O.CN(C)C=O.Cc1cc2c(O)cccc2[nH]1>>Cc1cc2c(OCc3ccccc3)cccc2n1Cc1ccccc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US05998433,COc1ccc(C(=O)c2ccc(C(=O)N3CCc4oc(CN(C)C)cc4C3)cc2)cc1.Cl>>COc1ccc(C(=O)c2ccc(C(=O)N3CCc4oc(CN(C)C)cc4C3)cc2)cc1.Cl,,CCOC(C)=O,CO,,,test
US20150031727A1,CCC(CC)N(Cc1cccc(-c2nc3sc4c(c3c(=O)o2)CCCC4)c1)C(=O)CCC(C)(C)C(=O)OC.Nc1ccc(CCN2CCOCC2)cc1>>CCC(CC)N(Cc1cccc(C(=O)Nc2sc3c(c2C(=O)Nc2ccc(CCN4CCOCC4)cc2)CCCC3)c1)C(=O)CCC(C)(C)C(=O)OC,,C1CCOC1,,[Cl-].[NH4+],C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US05344835,CC(=O)OC(C)=O.Nc1ccc(CCN2CCC(COC(c3ccccc3)c3ccccc3)CC2)cc1>>CC(=O)Nc1ccc(CCN2CCC(COC(c3ccccc3)c3ccccc3)CC2)cc1,,CC#N,,CCN(CC)CC,,test
US20150094281A1,COc1ccc(CO[C@@H](C)[C@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@H](CCC[C@H](NC(=O)OC(C)(C)C)C(=O)O)CCC(C)C)cc1>>CC(C)CC[C@@H](CCC[C@H](NC(=O)OC(C)(C)C)C(=O)O)[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@H](C)O,[Pd],C1CCOC1,,,,test
US20090099182A1,COc1cc(Cl)c(CN2CCC(C3CCCCC3)C2=O)c(Cl)c1>>O=C1C(C2CCCCC2)CCN1Cc1c(Cl)cc(O)cc1Cl,,CC(Cl)Cl,,BrB(Br)Br,,test
US20090118501A1,C1CCNCC1.CC(=O)N1CCC(N(C(=O)Nc2ncc(SCC(=O)O)s2)[C@@H]2CC[C@@H](C)CC2)CC1.CC(=O)N1CCC(N[C@@H]2CC[C@@H](C)CC2)CC1.CCOC(=O)CSc1cnc(N)s1.O=c1c2ccccc2nnn1O>>CC(=O)N1CCC(N(C(=O)Nc2ncc(SCC(=O)N3CCCCC3)s2)[C@@H]2CC[C@@H](C)CC2)CC1.CC(=O)N1CCC(N(C(=O)Nc2ncc(SCC(=O)O)s2)[C@@H]2CC[C@@H](C)CC2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CCN=C=NCCCN(C)C,test
US06391880B1,O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1.c1cc(C2CCN(CC3CCNCC3)CC2)ccn1>>O=S(=O)(c1ccc(C(F)(F)F)cc1)N1CCC(CN2CCC(c3ccncc3)CC2)CC1,,ClCCl,ClCCl,CCN(CC)CC,Cl,test
US20060100262A1,COC(=O)c1ccc2c(C3CCCCC3)c(Br)[nH]c2c1.COC(CBr)OC>>COC(=O)c1ccc2c(C3CCCCC3)c(Br)n(CC(OC)OC)c2c1,,CN(C)C=O,,[H-].[Na+],,test
US20070232645A1,CCCc1ccc2c(Cl)ccnc2n1.CN(C)C(=O)c1cccc(Oc2ccc(Cl)cc2N)c1>>CCCc1ccc2c(Nc3cc(Cl)ccc3Oc3cccc(C(=O)N(C)C)c3)ccnc2n1,,CCO,,,,test
US20130261107A1,O=C(c1ccc(F)cc1)N1CCc2nc(CO)oc2CC1.Oc1ccccc1>>O=C(c1ccc(F)cc1)N1CCc2nc(COc3ccccc3)oc2CC1,,ClCCl,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060148858A1,CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO.CCOC(=O)CCc1cc(O)nn1C1CCCCC1>>CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCOc1cc(CCC(=O)O)n(C2CCCCC2)n1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20110251194A1,CCn1c(=O)oc(=O)c2ccc(Br)cc21.N#CCC(N)=O>>CCn1c(N)c(C(N)=O)c(=O)c2ccc(Br)cc21,,CN(C)C=O,,Cl,[H-].[Na+],test
US20100305091A1,CC(C)(O)CN.Fc1ccc(-c2cnc3c(Br)cnn3c2)cn1>>CC(C)(O)CNc1ccc(-c2cnc3c(Br)cnn3c2)cn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05451686,CCCCCCCCCCCC(=O)OCC1=C(c2ccccc2)C(=O)OC1(C)O>>CC1(O)OC(=O)C(c2ccccc2)=C1CO,,C1CCOC1,,CC(=O)O,[Li+].[OH-],test
US20080153905A1,N#CC(C=O)c1cccc(Oc2ccccc2)c1>>N#CC(CO)c1cccc(Oc2ccccc2)c1,,CC(=O)O,CCO,[BH3-]C#N.[Na+],,test
US20070244159A1,COc1cc(C=O)cc(F)c1O>>O=Cc1cc(O)c(O)c(F)c1,,ClCCl,,BrB(Br)Br,,test
US06828315B1,COC1CCC(OC)O1.Nc1nnc2n(Cc3ccccc3)c(=O)c3cc(Br)ccc3n12>>O=c1c2cc(Br)ccc2n2c(-n3cccc3)nnc2n1Cc1ccccc1,,CC(=O)O,,,,test
US06429212B1,C[C@H](N)c1ccccc1.O=C1OC(=O)c2c1cccc2[N+](=O)[O-]>>C[C@@H](c1ccccc1)N1C(=O)c2cccc([N+](=O)[O-])c2C1=O,,ClC(Cl)Cl,,,,test
US20160251321A1,CCO/C=C/C(=O)NC(=O)Nc1cc(SCC(F)(F)F)c(C)cc1F>>Cc1cc(F)c(-n2ccc(=O)[nH]c2=O)cc1SCC(F)(F)F,,CCO,,O=S(=O)(O)O,,test
US20090311176A1,CCN(CC)C(=O)CC(C#N)C(=O)c1ccc(OC)cc1.NN>>CCN(CC)C(=O)Cc1c(N)n[nH]c1-c1ccc(OC)cc1,,CCO,,CC(=O)O,O,test
US20160075692A1,CC(C)COC(=O)Cl.O=C1NCCN1c1cccc2c1cnn2-c1ccccc1F>>CC(C)COC(=O)N1CCN(c2cccc3c2cnn3-c2ccccc2F)C1=O,,CC#N,,CCN(CC)CC,,test
US20110245241A1,CNC(=O)c1nc2n(c(=O)c1OCc1ccccc1)CCOC2(C)C.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CNC(=S)c1nc2n(c(=O)c1OCc1ccccc1)CCOC2(C)C,,C1CCOC1,,,,test
US05859011,CC(N)=CC(=O)OC(C)(C)C.COC(=O)CC(=O)CC(=O)OC.O=Cc1c(Cl)cccc1Cl>>COC(=O)CC1=C(C(=O)OC)C(c2c(Cl)cccc2Cl)C(C(=O)OC(C)(C)C)=C(C)N1,,CO,,,,test
US20110275611A1,Cl.c1ccc(CN2CCOC(c3nc(-c4ccccc4)c[nH]3)C2)cc1>>Cl.c1ccc(-c2c[nH]c(C3CNCCO3)n2)cc1,[Pd],CO,,,,test
US20120214803A1,COc1ccnc2c(N)c(Cl)ccc12>>COc1ccnc2c(N)cccc12,[Pd],CC(=O)O,,O=C[O-].[NH4+],,test
US05824691,C1CCNCC1.CS(=O)(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1Cl>>CS(=O)(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1N1CCCCC1,,O,,CCOC(C)=O,Cl,test
US20060199804A1,C1COCCN1.Clc1nccc(-c2nc(Br)cs2)n1>>Brc1csc(-c2ccnc(N3CCOCC3)n2)n1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20070054916A1,Brc1ccc2nc(NCCc3ccccn3)ncc2c1.OB(O)c1ccccc1>>c1ccc(-c2ccc3nc(NCCc4ccccn4)ncc3c2)cc1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20100029657A1,CCOC(=O)N1C2CCC1CC(c1ccnc3c(-c4cccc5[nH]ncc45)c(-c4ccncc4)nn13)C2>>c1cc(-c2c(-c3ccncc3)nn3c(C4CC5CCC(C4)N5)ccnc23)c2cn[nH]c2c1,,ClC(Cl)Cl,,C[Si](C)(C)I,,test
US04704464,COC(=O)[C@@H](N)Cc1ccc(Cl)cc1.N>>NC(=O)[C@@H](N)Cc1ccc(Cl)cc1,,CO,,Cl,,test
US20030060498A1,CI.Cc1c(CCNC(=O)OC(C)(C)C)c2cc(S(=O)(=O)c3ccccc3)ccc2n1C>>Cc1c(CCN(C)C(=O)OC(C)(C)C)c2cc(S(=O)(=O)c3ccccc3)ccc2n1C,,CN(C)C=O,,[H-].[Na+],,test
US20160137653A1,CCOC(=O)CC1CC=C(c2cnc3ccccc3c2)CC1>>CCOC(=O)CC1CCC(c2cnc3ccccc3c2)CC1,[Pd],CO,,O=C[O-].[NH4+],,test
US20160272621A1,CC(=O)c1cc(Cl)ncc1NC(=O)OC(C)(C)C.OCCO>>CC1(c2cc(Cl)ncc2N)OCCO1,,CCOC(C)=O,Cc1ccccc1,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20130131124A1,Nc1ccccc1C1CC1C1CC1>>NC1CCCCC1C1CC1C1CC1,[Ru],C1CCOC1,,[H][H],,test
US20110003793A1,CCCCOC(=O)N1CCc2c(n(C)c3cc(-n4ccc(CCc5ccccc5)nc4=O)ccc23)CC1.Cl>>Cl.Cn1c2c(c3ccc(-n4ccc(CCc5ccccc5)nc4=O)cc31)CCNCC2,,ClCCl,,,,test
US20150072976A1,CC(C)(C)OC(=O)N1CCC(S)CC1.COC(=O)c1ccc(-c2nc(CCl)c(C)o2)cc1>>COC(=O)c1ccc(-c2nc(CSC3CCN(C(=O)OC(C)(C)C)CC3)c(C)o2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120295884A1,CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)Nc1cccc(OC(F)(F)F)c1.O=C(O)C(F)(F)F>>O=C(Nc1cccc(OC(F)(F)F)c1)[C@@H]1CCCN1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20160045505A1,Nc1cnc2nc(-c3cc(NC(=O)N4CCCC4)ccc3F)cn2c1.O=CN1C(=O)c2ccccc2S1(=O)=O>>O=CNc1cnc2nc(-c3cc(NC(=O)N4CCCC4)ccc3F)cn2c1,,CN(C)C=O,,,,test
US03932433,CCOC(N)=S.COC(=O)C1CCCC(Br)C1=O>>COC(=O)C1CCCc2sc(=O)[nH]c21,,C1COCCO1,,,,test
US20060135614A1,COC(=O)Cc1cc(Br)c(Oc2cc(Br)c(O)c(Br)c2)c(Br)c1>>O=C(O)Cc1cc(Br)c(Oc2cc(Br)c(O)c(Br)c2)c(Br)c1,,C1CCOC1,,Cl,[Li+].[OH-],test
US20120295874A1,COC(=O)c1cccc2ccc(B3OC(C)(C)C(C)(C)O3)cc12>>CC1(C)OB(c2ccc3cccc(C(=O)O)c3c2)OC1(C)C,,C1CCOC1,,O,[Li+].[OH-],test
US20050277583A1,CC[C@H](C)[C@H](NC(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)OC(C)(C)C)C(=O)N1CCCCC1C(=O)OCc1ccccc1>>CC[C@H](C)[C@H](NC(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)OC(C)(C)C)C(=O)N1CCCCC1C(=O)O,[Pd],CO,,,,test
US20010027196A1,Cc1ccc(-c2nc(N)nc(S(C)=O)c2C#N)o1.NCc1ccccc1>>Cc1ccc(-c2nc(N)nc(NCc3ccccc3)c2C#N)o1,,COCCOC,,,,test
US20150045368A1,CC1(C)OC(=O)N(c2ccc(-c3cnc(F)c(-c4ccc5nncn5n4)c3)cc2)[C@H]1c1ccccc1.N>>CC1(C)OC(=O)N(c2ccc(-c3cnc(N)c(-c4ccc5nncn5n4)c3)cc2)[C@H]1c1ccccc1,,CS(C)=O,,,,test
US05550122,Cc1ccc(NC(=O)c2cc([N+](=O)[O-])cnc2Cl)c(O)c1>>Cc1ccc2c(c1)Oc1ncc([N+](=O)[O-])cc1C(=O)N2,,O,,c1ccncc1,,test
US20040220189A1,Brc1cncc2ncc(Br)n12.CC(C)N>>CC(C)Nc1nccn2c(Br)cnc12,,C1CCOC1,ClCCl,,,test
US20140275179A1,O=C(O)c1snc(-c2ccc(Cl)cc2)c1C(=O)O>>O=C(O)c1csnc1-c1ccc(Cl)cc1,,Clc1ccccc1Cl,,,,test
US05102890,CC(C)CCCC(=O)Cl.Cc1ccc2ccc(N3C(=O)c4ccccc4C3O)nc2n1>>Cc1ccc2ccc(N3C(=O)c4ccccc4C3OC(=O)CCCC(C)C)nc2n1,,CCN(CC)CC,,,,test
US04290971,CC(=O)NC(=S)Nc1cccc(I)c1.CI>>CSC(=NC(C)=O)Nc1cccc(I)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140275111A1,CCOc1cc(OCc2ccccc2)ncc1-c1ccc(CC(=O)Nc2ccc(OCCOCc3ccccc3)c(C(F)(F)F)c2)c(F)c1>>CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2ccc(OCCO)c(C(F)(F)F)c2)c(F)c1,[Pd],CO,,,,test
US20120225881A1,CCN(CC)CC.COC(=O)C(Br)CBr.COC(=O)C1C[N@@]1[C@@H](C)c1ccccc1>>COC(=O)C1C[N@@]1[C@@H](C)c1ccccc1.O=C([O-])C1CN1,,Cc1ccccc1,,,,test
US20110201616A1,COCOc1cc2c(cc1N(C[C@H](C)F)S(=O)(=O)c1nc(C)cs1)CCC2>>Cc1csc(S(=O)(=O)N(C[C@H](C)F)c2cc3c(cc2O)CCC3)n1,,CO,,C1COCCO1,Cl,test
US20100317647A1,CO[C@H]1C[C@@H](S(=O)(=O)c2ccc(F)cc2Cl)C[C@@H]1C(=O)NC1(C#N)CC1.Oc1ccc(F)cc1>>CO[C@H]1C[C@@H](S(=O)(=O)c2ccc(Oc3ccc(F)cc3)cc2Cl)C[C@@H]1C(=O)NC1(C#N)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100310512A1,CCOC(=O)c1ccc(-n2ccc(C(=O)O)cc2=O)cc1>>O=C(O)c1ccc(-n2ccc(C(=O)O)cc2=O)cc1,,C1CCOC1,,Cl,[Na+].[OH-],test
US04339575,COCOC(=O)C1=C(Cl)CS[C@@H]2[C@H](N3C(=O)C(c4ccccc4)NC3(C)C)C(=O)N12>>CC1(C)NC(c2ccccc2)C(=O)N1[C@@H]1C(=O)N2C(C(=O)O)=C(Cl)CS[C@H]12,,CO,,,,test
US20050032786A1,COC(=O)c1ccc(C#N)nc1.COC(=O)c1ccccc1S>>COC(=O)c1ccc(-c2nc(=O)c3ccccc3s2)nc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20090042925A1,CC(C)Cn1c(CCl)nc2c(N)nc3cc(Br)ccc3c21.O=C1c2ccccc2C(=O)N1O>>CC(C)Cn1c(CON2C(=O)c3ccccc3C2=O)nc2c(N)nc3cc(Br)ccc3c21,,CN(C)C=O,,CCN(CC)CC,CCOCC,test
US05399703,COC(=O)COc1ccc(C(=O)Nc2ccccc2Sc2ccccc2-c2nnn[nH]2)cc1>>O=C(O)COc1ccc(C(=O)Nc2ccccc2Sc2ccccc2-c2nnn[nH]2)cc1,,CCO,,[Na+].[OH-],,test
US20100222398A1,COc1ccc(CC#N)cc1.[N-]=[N+]=Nc1ccc(C(F)(F)F)cc1Cl>>COc1ccc(-c2nnn(-c3ccc(C(F)(F)F)cc3Cl)c2N)cc1,,CCO,CCOC(C)=O,C[O-].[Na+],,test
US20080207598A1,CNC(=O)CCl.OC[C@@H]1CN(Cc2nc(-c3cn(CC4CCOCC4)c4c(Cl)cccc34)no2)CCN1>>CNC(=O)CN1CCN(Cc2nc(-c3cn(CC4CCOCC4)c4c(Cl)cccc34)no2)C[C@H]1CO,,CN(C)C=O,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20070254872A1,C=Cc1ccnc2ccc(OC)nc12.CN(Cc1ccc2c(n1)NC(=O)CS2)C(=O)C1CNCCO1>>COc1ccc2nccc(CCN3CCOC(C(=O)N(C)Cc4ccc5c(n4)NC(=O)CS5)C3)c2n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccccc23)cc1.Nc1ccc2[nH]cnc2c1>>c1ccc2c(c1)nc(Nc1ccc3[nH]cnc3c1)c1n[nH]cc12,C1COCCO1,CO,,Cl,,test
US20070244159A1,CC(C)(C)C#Cc1cc([N+](=O)[O-])c(F)cc1N.CCCC(=O)Cl>>CCCC(=O)Nc1cc(F)c([N+](=O)[O-])cc1C#CC(C)(C)C,,ClCCl,,CCN(CC)CC,O,test
US20110275611A1,C[C@@H]1CO[C@H](CNS(=O)(=O)c2ccccc2)CN1c1cc(-c2ccc(C#N)c(F)c2)nc(N)n1.NN>>C[C@@H]1CO[C@H](CNS(=O)(=O)c2ccccc2)CN1c1cc(-c2ccc3c(N)n[nH]c3c2)nc(N)n1,,CCO,,O,,test
US20110046132A1,COCCOCCl.O=[N+]([O-])c1cc2nc(Cl)[nH]c2cc1Cl>>COCCOCn1c(Cl)nc2cc([N+](=O)[O-])c(Cl)cc21,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20080292585A1,CN(C)CCN1C(=O)c2cccc3cc4cccc(N)c4c(c23)C1=O.COc1ccccc1N=C=S>>COc1ccccc1NC(=S)Nc1cccc2cc3cccc4c3c(c12)C(=O)N(CCN(C)C)C4=O,,CC#N,,,,test
US20150361284A1,OCCCl.Oc1ccc(-c2ccccc2)cc1>>OCCOc1ccc(-c2ccccc2)cc1,,ClCCl,,O,[Na+].[OH-],test
US20070049593A1,CC1(C)OB(c2cc(F)ccc2N)OC1(C)C.COC(=O)c1ccc2c(C3CCCCC3)c(Br)[nH]c2c1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3cc(F)ccc3N)[nH]c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])O.[Na+],,test
US20120071482A1,COc1ccc(C2OC[C@@H]3C[C@@H](N)C[C@@H]3O2)cc1.Clc1cc(Cl)ncn1>>COc1ccc(C2OC[C@@H]3C[C@@H](Nc4cc(Cl)ncn4)C[C@@H]3O2)cc1,,CCO,,CCN(C(C)C)C(C)C,,test
US20030078251A1,CC(=O)Cl.COc1cccc([C@H]2O[C@H](CC(=O)Nc3cc(CCC(=O)O)ccc3F)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC>>COc1cccc([C@H]2O[C@H](CC(=O)Nc3cc(CCC(=O)O)ccc3F)C(=O)N(CC(C)(C)COC(C)=O)c3ccc(Cl)cc32)c1OC,,CCOC(C)=O,,O,c1ccncc1,test
US20080009530A1,CCOC(=O)/C(C)=C/c1ccc(OC(C)C)cc1Oc1ncc(C(F)(F)F)cc1Cl>>C/C(=C\c1ccc(OC(C)C)cc1Oc1ncc(C(F)(F)F)cc1Cl)C(=O)O,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20080269268A1,Nc1ccc(Cc2ccnc3[nH]ccc23)c(F)c1.Nc1nc(Cl)cc(C(F)(F)F)n1>>Nc1nc(Nc2ccc(Cc3ccnc4[nH]ccc34)c(F)c2)cc(C(F)(F)F)n1,,Cl,O,CO,[Na+].[OH-],test
US20090318441A1,CCC(CC)N1C(=O)C(Br)(Br)c2cnc(Cl)nc21>>CCC(CC)N1C(=O)Cc2cnc(Cl)nc21,[Zn],C1CCOC1,CC(=O)O,,,test
US20140296246A1,CN(C)C=O.Cc1noc(C)c1-c1cc(I)c(N)c([N+](=O)[O-])c1>>CNc1c(I)cc(-c2c(C)noc2C)cc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04171356,BrCc1ccccc1.[N-]=[N+]=NC[C@@H]1C[C@H](O)C(O)=C(O)O1>>[N-]=[N+]=NC[C@@H]1C[C@H](OCc2ccccc2)C(O)=C(O)O1,,CCOCC,CO,CN(C)C=O,[H-].[Na+],test
US20090149448A1,CC(C)(C)OC(=O)COc1ccc(Cl)cc1C=O>>CC(C)(C)OC(=O)COc1ccc(Cl)cc1CO,,CCO,,[BH4-].[Na+],,test
US20100179168A1,Cc1ccc(-c2ccc(S(=O)(=O)Nc3cccc(NC(=O)C(C)(C)NC(=O)OC(C)(C)C)c3)cc2F)o1.Cl>>Cc1ccc(-c2ccc(S(=O)(=O)Nc3cccc(NC(=O)C(C)(C)N)c3)cc2F)o1.Cl,,C1COCCO1,,,,test
US20090105275A1,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCN(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)C2)c1>>CC(C)CC(C(=O)O)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCN(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)C2)c1,,CCO,,[K+].[OH-],,test
US20080207708A1,O=C(O)c1cc(C(F)(F)F)ccc1OCc1ccccc1.[Li]C>>CC(=O)c1cc(C(F)(F)F)ccc1OCc1ccccc1,,CCOCC,CCOCC,Cl,,test
US20070060754A1,CCOCc1nc2c(N)nc3cc(OCCCCCCN)ccc3c2n1CC(C)(C)NS(C)(=O)=O.CS(=O)(=O)OS(C)(=O)=O>>CCOCc1nc2c(N)nc3cc(OCCCCCCNS(C)(=O)=O)ccc3c2n1CC(C)(C)NS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20050119320A1,CCNC(=O)Nc1nc(C)c(-c2cccc([N+](=O)[O-])c2)s1>>CCNC(=O)Nc1nc(C)c(-c2cccc(N)c2)s1,[Pd],C1CCOC1,CCOC(C)=O,,,test
US20050107402A1,COC(=O)[C@@H]1C[C@@H]1c1ccc(Br)cc1>>O=C(O)C1CC1c1ccc(Br)cc1,,C1CCOC1,CO,[Li+].[OH-],,test
US20150038503A1,CCI.O=c1ccc(-c2ccc(C(F)(F)F)cc2Oc2ccc3nnc(Cl)n3n2)c[nH]1>>CCOc1ccc(-c2ccc(C(F)(F)F)cc2Oc2ccc3nnc(Cl)n3n2)cn1,O=[Ag],Cc1ccccc1,ClCCl,,,test
US20130303492A1,NC(=O)c1c(Nc2cccnc2)n[nH]c1N.O=Cc1cccc(O)c1>>NC(=O)c1c(Nc2cccnc2)n[nH]c1N=Cc1cccc(O)c1,C1CCNCC1,CCO,,,,test
US05102877,COC[C@@H]1C[C@@H](OS(C)(=O)=O)CN1C(=O)OC(C)(C)C.[C-]#N>>COC[C@@H]1C[C@H](C#N)CN1C(=O)OC(C)(C)C,,CS(C)=O,,CCOC(C)=O,O,test
US05728724,Br[Mg]c1ccc2ccccc2c1.COc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(N(C)C)sc2c1>>COc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(-c3ccc4ccccc4c3)sc2c1,,C1CCOC1,ClCCl,CO,,test
US20160157491A1,CNN.CS/C(=C1/Cc2cc(Br)ccc2C1=O)c1ccc(OC(F)(F)F)cc1>>Cn1nc2c(c1-c1ccc(OC(F)(F)F)cc1)Cc1cc(Br)ccc1-2,,CCCO,,,,test
US20150038528A1,CC(C)(N)CC(=O)O.CCOC(=O)c1nc(C#N)c2cc(OCc3ccccc3)ccc2c1O>>CC(C)(CC(=O)O)NC(=O)c1nc(C#N)c2cc(OCc3ccccc3)ccc2c1O,,CN(C)C=O,O,C[O-].[Na+],,test
US20120165298A1,Clc1ccc(-c2ccccc2CI)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>Clc1ccc(-c2ccccc2C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.[I-],,Cc1ccccc1,,,,test
US05156763,COc1cc(F)c(C(=O)Cl)c(F)c1.N>>COc1cc(F)c(C(N)=O)c(F)c1,,COCCOCCOC,,,,test
US20090156604A1,CC(C)(C)OC(=O)N1CCC(C(=O)N/N=C(\N)c2ccccn2)CC1>>CC(C)(C)OC(=O)N1CCC(c2n[nH]c(-c3ccccn3)n2)CC1,,CCO,,,,test
US04894386,CCCn1cc(Cc2ccc(C(=O)OC)cc2OC)c2cc(CC(C)C(=O)O)ccc21.O=C(Cl)C(=O)Cl>>CCCn1cc(Cc2ccc(C(=O)OC)cc2OC)c2cc(CC(C)C(=O)Cl)ccc21,,ClCCl,,,,test
US20130210810A1,CN1CCNCC1.O=[N+]([O-])C1(F)C=C(C(F)(F)F)C=CC1>>CN1CCN(c2ccc([N+](=O)[O-])cc2C(F)(F)F)CC1,,CO,O,,,test
US20140275179A1,Cc1ccccc1-c1snc(Cl)c1C(=O)O>>Cc1ccccc1-c1snc(Cl)c1CO,,C1CCOC1,,,,test
US20100197675A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.N[C@H](CO)CNCC12CC3CC(CC(C3)C1)C2>>CC(C)(C)[Si](OC[C@@H](N)CNCC12CC3CC(CC(C3)C1)C2)(c1ccccc1)c1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20130203746A1,Cc1ccc(C2CO2)cc1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>Cc1ccc(C(O)Cn2c3c(c4cc(C)ccc42)CN(C)CC3)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20060205741A1,COc1ccc2c(C)c(-c3cnc(OC)nc3OC)c(=O)oc2c1.O=C1CCC(=O)N1Br>>COc1ccc2c(CBr)c(-c3cnc(OC)nc3OC)c(=O)oc2c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20120035214A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cn1ccc([C@@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2c2ccc(Br)cc2Cl)cc1=O>>Cn1ccc([C@@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2c2ccc(B3OC(C)(C)C(C)(C)O3)cc2Cl)cc1=O,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20140315879A1,CC(C)Oc1ncc(OCc2cc(F)c(C(=O)O)cc2F)cc1Cl.NS(=O)(=O)N1CCC1>>CC(C)Oc1ncc(OCc2cc(F)c(C(=O)NS(=O)(=O)N3CCC3)cc2F)cc1Cl,CN(C)c1ccncc1,CS(C)=O,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US20080176872A1,Nc1cc(C2CC2)[nH]n1.O=[N+]([O-])c1ccc(F)c(F)c1F>>O=[N+]([O-])c1ccc(F)c(F)c1Nc1cc(C2CC2)[nH]n1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20120015941A1,CC(C)(C)OC(=O)NC(N)=S.O=C(CCl)CCl>>CC(C)(C)OC(=O)Nc1nc(CCl)cs1,,CC(C)=O,,O=C([O-])O.[Na+],,test
US05330996,CC(C)[Si](OC(CO)C(Cc1ccccc1)NC(=O)OC(C)(C)C)(C(C)C)C(C)C>>CC(C)[Si](O[C@@H](CO)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C)(C(C)C)C(C)C,,CO,,,,test
US20030078249A1,C=CCC[C@@H](COCc1ccccc1)N1C(=O)c2ccccc2C1=O>>C=CCC[C@H](N)COCc1ccccc1,,CCO,,NN,O,test
US20080293776A1,CC#N.CC(=O)O.N#Cc1c(Cc2ccc(N)c(OCc3ccccc3)c2)cccc1OCc1ccccc1>>CCOC(=O)CNc1ccc(Cc2cccc(OCc3ccccc3)c2C#N)cc1OCc1ccccc1,,CC#N,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150191483A1,C=CC1(C(=O)O)CCS(=O)(=O)CC1.O=S(=O)(c1ccc(F)cc1)[C@@]1(c2ccc(C(F)(C(F)(F)F)C(F)(F)F)cc2)CCNC1>>C=CC1(C(=O)N2CC[C@](c3ccc(C(F)(C(F)(F)F)C(F)(F)F)cc3)(S(=O)(=O)c3ccc(F)cc3)C2)CCS(=O)(=O)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060155121A1,C=O.CC(=O)Nc1c(C)cc(NCc2ccc(C(F)(F)F)cc2)cc1C>>CC(=O)Nc1c(C)cc(N(C)Cc2ccc(C(F)(F)F)cc2)cc1C,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US20130178459A1,COc1cc(C)c2c(c1-c1ccc([C@@H](C)CNC(=O)OC(C)(C)C)cc1)c1cc(Cl)sc1c(=O)n2COCC[Si](C)(C)C.ClCCl>>COc1cc(C)c2[nH]c(=O)c3sc(Cl)cc3c2c1-c1ccc([C@@H](C)CN)cc1.Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120302578A1,N#Cc1ccc(-c2cnc(Cl)o2)cc1.Nc1cccc(-c2nnn[nH]2)c1>>N#Cc1ccc(-c2cnc(Nc3cccc(-c4nnn[nH]4)c3)o2)cc1,,CC(C)O,,,,test
US20040034017A1,ClCCCCBr.O=C1c2ccc(OC3CCCCO3)cc2OC(c2ccc(O)cc2)C1c1ccc(OC2CCCCO2)cc1>>O=C1c2ccc(OC3CCCCO3)cc2OC(c2ccc(OCCCCCl)cc2)C1c1ccc(OC2CCCCO2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100249146A1,Cn1ccc(Nc2ncnc3ccc(O)cc23)n1.O=[N+]([O-])c1ccc(Br)cn1>>Cn1ccc(Nc2ncnc3ccc(Oc4ccc([N+](=O)[O-])nc4)cc23)n1,,CN(C)C=O,,[H-].[Na+],,test
US20070066624A1,NCc1ccc(CN2CCC(N3C(=O)N(C4CCOCC4)C[C@H]3c3ccccc3)CC2)cc1.O=C=Nc1ccccc1>>O=C(NCc1ccc(CN2CCC(N3C(=O)N(C4CCOCC4)C[C@H]3c3ccccc3)CC2)cc1)Nc1ccccc1,,CC(C)O,,,,test
US20100297113A1,COc1cc(CO)c(OC)c2ccccc12.CSSC>>COc1c(CO)c(SC)c(OC)c2ccccc12,,C1CCOC1,O,Cl,[Li]CCCC,test
US20140274960A1,N#Cc1cccc2c1CCNC2>>N#Cc1cccc2c1CCN=C2,O=[Mn]=O,ClCCl,,,,test
US20100009969A1,CC1(C)CNC(=O)C(Br)C(=O)C1.NC(=S)c1ccc(OCCCCl)cc1>>CC1(C)CNC(=O)c2sc(-c3ccc(OCCCCl)cc3)nc2C1,,CN(C)C=O,,,,test
US20110015199A1,CCOC(=O)C1CCNCC1.O=C(O)C1(C(F)(F)F)CC1>>CCOC(=O)C1CCN(C(=O)C2(C(F)(F)F)CC2)CC1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20150005282A1,Cc1cc(O[C@@H]2CCOC2)cc(C)c1Br.O=C1CCC(=O)N1Br>>Cc1cc(O[C@@H]2CCOC2)cc(CBr)c1Br,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20040023807A1,BrC(Br)(Br)Br.COc1cc(CO)c(F)cc1Cl>>COc1cc(CBr)c(F)cc1Cl,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US06492416B1,CCC1(CC)OC(c2ccc(SC)cc2)=CC1=O.O=S([O-])OO>>CCC1(CC)OC(c2ccc(S(C)(=O)=O)cc2)=CC1=O,,O,,CO,,test
US20070088018A1,Fc1cccc(F)n1.NCC1CN(C(=O)c2ccc(S(=O)(=O)n3cc(-c4ccccc4)c4ccccc43)cc2)C1>>O=C(c1ccc(S(=O)(=O)n2cc(-c3ccccc3)c3ccccc32)cc1)N1CC(CNc2cccc(F)n2)C1,,C1COCCO1,,CCN(CC)CC,,test
US20090054463A1,CCOC(=O)CP(=O)(OCC)OCC.O=C(c1ccc(F)cc1)c1ccc(F)cc1>>CCOC(=O)C=C(c1ccc(F)cc1)c1ccc(F)cc1,,CCOCC,Cc1ccccc1,[H-].[Na+],,test
US20140171390A1,COc1c(CC(NC(=O)CC2CCC(CNC(=O)OCc3ccccc3)CC2)B2OC3CC4CC(C4(C)C)C3(C)O2)cccc1C(=O)OC(C)(C)C>>COc1c(CC(NC(=O)CC2CCC(CN)CC2)B2OC3CC4CC(C4(C)C)C3(C)O2)cccc1C(=O)OC(C)(C)C,[Pd],CO,,,,test
US04232028,COc1ccc2c3c1O[C@H]1C(=O)C[C@@H](C)[C@@]4(OC)[C@@H](C2)N(C)CC[C@]314.N#CBr>>COc1ccc2c3c1O[C@H]1C(=O)C[C@@H](C)[C@@]4(OC)[C@@H](C2)N(C#N)CC[C@]314,,ClC(Cl)Cl,,O=C([O-])[O-].[Na+].[Na+],,test
US20100216814A1,CC(=CBr)c1cccnc1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>C/C(=C\n1c2c(c3cc(C)ccc31)CN(C)CC2)c1cccnc1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20140087949A1,CCOC(=O)/C=C(\C#CC1(O)C(C)=CC(=O)CC1(C)C)C(F)(F)F>>CC1=CC(=O)CC(C)(C)C1(O)C#C/C(=C\C(=O)O)C(F)(F)F,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20150197509A1,CC(C)(C)OC(=O)NCc1ccc(F)c(-c2cnc(C(F)(F)F)nc2)c1>>NCc1ccc(F)c(-c2cnc(C(F)(F)F)nc2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070281936A1,Cc1ccc(C)c(C#N)n1>>Cc1ccc(C)c(CN)n1,[Ni],CCO,,,,test
US20140315885A1,CCOc1c(OCC)c(=O)c1=O.NC1CC1>>CCOc1c(NC2CC2)c(=O)c1=O,,CCO,,CCN(CC)CC,,test
US20040018994A1,O=C/C=C/c1ccc(-c2cnccn2)cc1>>OCC=Cc1ccc(-c2cnccn2)cc1,,CCO,,[BH4-].[Na+],,test
US20130040981A1,CC1(C)CC(=O)C2=C(C1)Nc1[nH]nc(C(=O)OC(C)(C)C)c1C2/C=C/c1ccc(-c2cccc(F)c2)cn1>>CC1(C)CC(=O)C2=C(C1)Nc1[nH]nc(C(=O)O)c1C2/C=C/c1ccc(-c2cccc(F)c2)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100056516A1,O=c1c(-c2ccccc2)c(O)c2cc(S(=O)(=O)Nc3ccccc3)cnc2n1OCc1ccccc1>>O=c1c(-c2ccccc2)c(O)c2cc(S(=O)(=O)Nc3ccccc3)cnc2n1O,[Pd],CCO,,,,test
US04616014,CI.Cc1nc(=O)[nH]nc1-c1ccccc1>>Cc1nc(=O)n(C)nc1-c1ccccc1,,CO,,[K],,test
US20060211577A1,CNC(C)C.Cn1c(C(F)(F)F)cc(=O)n(-c2cc(S(=O)(=O)N=C=O)c(Cl)cc2F)c1=O>>CC(C)N(C)C(=O)NS(=O)(=O)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl,,ClCCCl,,,,test
US20090275588A1,CCN.O=Cc1ccccn1>>CCNCc1ccccn1,,C1CCOC1,,,,test
US04846882,CCOCc1ccc(F)cc1Br.O=[N+]([O-])O>>CCOCc1cc([N+](=O)[O-])c(F)cc1Br,,ClCCCl,,O=S(=O)(O)O,,test
US20080132495A1,NCc1c(F)cccc1F.Nc1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1.O=C(n1ccnc1)n1ccnc1>>NC(=O)N(Cc1c(F)cccc1F)c1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1,,C1CCOC1,,,,test
US04642308,COc1ccc2ccc(N)nc2n1.O=C(O)c1cccs1>>COc1ccc2ccc(NC(=O)c3cccs3)nc2n1,,O,,CCO,,test
US04789683,BrB(Br)Br.CCN1CCCC1CNC(=O)c1c(OC)cccc1OC>>CCN1CCCC1CNC(=O)c1c(O)ccc(Br)c1OC,,ClCCl,,Cl,O,test
US20100069416A1,Cc1cccc(-c2cc[nH]c(=O)n2)n1.ClCCCCBr>>Cc1cccc(-c2ccn(CCCCCl)c(=O)n2)n1,,CN(C)C=O,,O,[H-].[Na+],test
US20150336986A1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.N[C@H](CS)C(=O)O>>N[C@@H](CO)CSC(c1ccccc1)(c1ccccc1)c1ccccc1,,C1CCOC1,,B,,test
US20020156087A1,N#Cc1ccc(-c2nc(NCCN)ncc2-c2ncc[nH]2)cc1.O=C(O)c1cccc([N+](=O)[O-])c1>>N#Cc1ccc(-c2nc(NCCNC(=O)c3cccc([N+](=O)[O-])c3)ncc2-c2ncc[nH]2)cc1,CN(C)c1ccncc1,CC(=O)N(C)C,CCOC(C)=O,CCN=C=NCCCN(C)C,Cl,test
US20060241115A1,CN1CC=C(c2cc(N)cc(C(F)(F)F)c2)CC1>>CN1CCC(c2cc(N)cc(C(F)(F)F)c2)CC1,,CCO,,,,test
US20100305052A1,COc1cc(C#N)ccc1C=O.N#CC=C([O-])C(F)(F)F.Nc1cc[nH]c(=O)c1>>COc1cc(C#N)ccc1C1C(C#N)=C(C(F)(F)F)Nc2cc[nH]c(=O)c21,,CC(C)O,,CC(=O)O,,test
US05318966,COc1cccc2c1CC[C@H]1[C@@H]2CCN1CC1CCCCC1>>Oc1cccc2c1CC[C@H]1[C@@H]2CCN1CC1CCCCC1,,Br,,[Na+].[OH-],,test
US20040158067A1,CCc1cccc(CC)c1-c1cc(OC)c(C(=O)OC)c(C(F)(F)F)n1>>CCc1cccc(CC)c1-c1cc(OC)c(CO)c(C(F)(F)F)n1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20020107278A1,CC(C)(C)OC(=O)N1CCc2c(n(CCS(=O)(=O)c3ccccc3)c3ccccc23)CC1>>O=S(=O)(CCn1c2c(c3ccccc31)CCNCC2)c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05168103,CCOP(=O)(CCNCCCCNC(=O)OC(C)(C)C)OCC.CCOc1c(OCC)c(=O)c1=O>>CCOc1c(N(CCCCNC(=O)OC(C)(C)C)CCP(=O)(OCC)OCC)c(=O)c1=O,,CCO,,,,test
US20090306066A1,CN(Cc1ccncc1)c1nc(Cl)nc(NNC(=O)[C@H](CC2CCCC2)CN(C=O)OC2CCCCO2)c1F>>CN(Cc1ccncc1)c1nc(Cl)nc(NNC(=O)[C@H](CC2CCCC2)CN(O)C=O)c1F,,CC(=O)O,O,,,test
US20120202785A1,CC(N=[N+]=[N-])c1sc2ccccc2c1-c1ccccc1>>CC(N)c1sc2ccccc2c1-c1ccccc1,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20020099212A1,COC(=O)c1ccc2nc(C)n(Cc3ccc(N)cc3Cl)c2n1.O=C=Nc1ccccc1>>COC(=O)c1ccc2nc(C)n(Cc3ccc(NC(=O)Nc4ccccc4)cc3Cl)c2n1,,Cc1ccccc1,,,,test
US20080182802A1,CCc1ccc(Cc2cc(Br)c(OC)cc2Cl)cc1.O=C1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>CCc1ccc(Cc2cc([C@]3(O)O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)c(OC)cc2Cl)cc1,,C1CCOC1,,[Li]CCCC,,test
US20060035912A1,CC(C)n1cc(C(=O)c2cncc(N)c2)c2c(N)ncnc21.O=S(=O)(Cl)c1cc(F)cc(F)c1>>CC(C)n1cc(C(=O)c2cncc(NS(=O)(=O)c3cc(F)cc(F)c3)c2)c2c(N)ncnc21,,c1ccncc1,,,,test
US20110207711A1,CON(C)C(=O)C1CN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CC(C=O)C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120157425A1,CC(=O)N[C@@H](C)c1ccc(C2CCNCC2)cc1.O=C(Br)CBr>>CC(=O)N[C@@H](C)c1ccc(C2CCN(C(=O)CBr)CC2)cc1,,ClCCl,,,,test
US06001867,COC(=O)COc1ccc(-c2cccc3sc4ccccc4c23)cc1>>O=C(O)COc1ccc(-c2cccc3sc4ccccc4c23)cc1,,C1CCOC1,CO,[K+].[OH-],,test
US20130157998A1,CCO.O=C(O)Cc1cccc(Br)c1>>CCOC(=O)Cc1cccc(Br)c1,O=S(=O)(O)O,,,,,test
US20070191372A1,CN(CCNC(=O)C(F)(F)F)CCNc1n[n+]([O-])c2ccccc2[n+]1[O-].O=C(c1cccc2nc3ccccc3nc12)n1ccnc1>>CN(CCNC(=O)c1cccc2nc3ccccc3nc12)CCNc1n[n+]([O-])c2ccccc2[n+]1[O-],,CO,,N,,test
US20160024021A1,CCS(=O)(=O)Cl.CNC(=O)c1cc(CCc2cnc(Nc3cn[nH]c3)nc2)c(F)c(OC)c1>>CCS(=O)(=O)n1cc(Nc2ncc(CCc3cc(C(=O)NC)cc(OC)c3F)cn2)cn1,,C1CCOC1,CN(C)C=O,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20100152160A1,CC(C)(C)OC(=O)N1CCC(Cc2ccc(F)cc2)(Cn2ccnc2)CC1>>Fc1ccc(CC2(Cn3ccnc3)CCNCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050176701A1,CC(O)c1cc(Br)ccc1Cl>>CC(=O)c1cc(Br)ccc1Cl,,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20140030221A1,COC(=O)C1(C)CCCN(C(=O)[C@H](C)NC(=O)[C@@H](NC(=O)C(C)(C)/C=C/c2ccc3ccc([C@@H](C)OC(C)=O)nc3c2)C(C)C)N1>>CC(C)[C@H](NC(=O)C(C)(C)/C=C/c1ccc2ccc([C@@H](C)O)nc2c1)C(=O)N[C@@H](C)C(=O)N1CCCC(C)(C(=O)O)N1,,C1CCOC1,O,[Li+].[OH-],,test
US20150320702A1,CCN.O=C1C=C(Br)C(=O)c2ccccc21>>CCNC1=CC(=O)c2ccccc2C1=O,,CCO,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20120232056A1,COC(=O)c1ccc2nc(-c3ccc4scnc4c3)c(N(C)C(C)C)nc2c1>>CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1ccc2scnc2c1,,CO,,O,[Na+].[OH-],test
US20040171606A1,NO.O=Cc1ccc2c(c1)CCN(C(=O)C(F)(F)F)CC2>>O=C(N1CCc2ccc(C=NO)cc2CC1)C(F)(F)F,,c1ccncc1,,Cl,,test
US20050159599A1,O=C(OO)c1cccc(Cl)c1.O=C(c1c(F)cccc1F)N1COCN(c2ccc(SC(F)(F)F)cc2F)C1=O>>O=C(c1c(F)cccc1F)N1COCN(c2ccc(S(=O)C(F)(F)F)cc2F)C1=O,,ClC(Cl)Cl,,,,test
US20030130278A1,C#CCc1ccccc1.COC(=O)c1ccc(Cn2c(=O)c3cc(I)ccc3n(C)c2=O)cc1>>COC(=O)c1ccc(Cn2c(=O)c3cc(C#CCc4ccccc4)ccc3n(C)c2=O)cc1,[Cu]I,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20040116698A1,CSCCC(N)CO.Cn1c(=O)c(Oc2ccccc2F)cc2cnc(S(C)(=O)=O)nc21>>CSCCC(CO)Nc1ncc2cc(Oc3ccccc3F)c(=O)n(C)c2n1,,CN1CCCC1=O,,CO,O,test
US20110005947A1,CC(=O)Nc1cccc(Nc2ncc(C(N)=O)c(NCC3CCCNC3)n2)c1.O=C=Nc1ccc(F)cc1>>CC(=O)Nc1cccc(Nc2ncc(C(N)=O)c(NCC3CCCN(C(=O)Nc4ccc(F)cc4)C3)n2)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040157881A1,COC(=O)c1ccc(-c2cc(-c3ccccc3)on2)cc1>>O=C(O)c1ccc(-c2cc(-c3ccccc3)on2)cc1,,O,,CC(=O)O,Cl,test
US06255305B1,CCCn1cnc(CO[Si](C)(C)C(C)(C)C)n1>>CCCn1cnc(CO)n1,,CCO,,CO,[Na+].[OH-],test
US20050209226A1,C1CC(OCC2CC2)CCN1.O=C1COc2ccc(F)cc2N1CCCCl>>O=C1COc2ccc(F)cc2N1CCCN1CCC(OCC2CC2)CC1,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US05534515,BrBr.Cc1cc2cnnc(OCc3ccc(F)cc3)c2n1Cc1ccccc1>>Cc1c(Br)c2cnnc(OCc3ccc(F)cc3)c2n1Cc1ccccc1,,ClCCl,,,,test
US20110039893A1,CCOC(=O)C=Cc1ccc(OC)cc1.C[N+](=O)[O-]>>CCOC(=O)CC(C[N+](=O)[O-])c1ccc(OC)cc1,,O,,C1CCC2=NCCCN2CC1,,test
US20040106645A1,BrP(Br)Br.CC(O)c1ccc2ncccc2c1>>CC(Br)c1ccc2ncccc2c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20020115680A1,CC(C(=O)O)(c1ccccc1)c1ccccc1.O=C(Cl)C(=O)Cl>>CC(C(=O)Cl)(c1ccccc1)c1ccccc1,CN(C)C=O,ClCCl,,,,test
US20150018547A1,COC(=O)Cc1csc2c(F)c(O)cc(C)c12.Cc1nc(C(F)(F)F)ccc1CO>>COC(=O)Cc1csc2c(F)c(OCc3ccc(C(F)(F)F)nc3C)cc(C)c12,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US05679683,CCOC(=O)c1c(N)[nH]c2ccccc12.Cl.N#CN>>CCOC(=O)c1c(NC(=N)N)[nH]c2ccccc12.Cl,,C1COCCO1,,,,test
US20140275083A1,C[C@H](NC(=O)OC(C)(C)C)c1nnc(-c2ccc(Cl)cc2)s1>>C[C@H](N)c1nnc(-c2ccc(Cl)cc2)s1,,C1COCCO1,,Cl,,test
US20120108619A1,NN.O=C(c1ccc(Br)cc1F)C(F)(F)F>>FC(F)(F)c1n[nH]c2cc(Br)ccc12,,CCCCO,O,,,test
US20150038528A1,CC(C)(N)CC(=O)O.COC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O>>CC(C)(CC(=O)O)NC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O,,CN(C)C=O,O,Cl,C[O-].[Na+],test
US20160257670A1,CC(C)(C)OC(=O)N1CC2C(C1)C2C(=O)Nc1ccns1.Cl>>Cl.O=C(Nc1ccns1)C1C2CNCC21,,C1COCCO1,,,,test
US20120083476A1,Clc1ccc(Oc2cccc(CN3CCC4(CCNCC4)C3)c2)cc1.O=C(Nc1ccc(-n2nccn2)nc1)Oc1ccccc1>>O=C(Nc1ccc(-n2nccn2)nc1)N1CCC2(CCN(Cc3cccc(Oc4ccc(Cl)cc4)c3)C2)CC1,,CCOC(C)=O,CS(C)=O,Cl,,test
US06174913B1,CC(=O)Cl.CC(O)c1cc2c(s1)C(=O)c1ccsc1C2=O>>CC(=O)OC(C)c1cc2c(s1)C(=O)c1ccsc1C2=O,,ClCCCl,,,,test
US04182874,CC(C)Nc1nc(Cl)nc(Cl)n1.CCN>>CCNc1nc(Cl)nc(NC(C)C)n1,,Cc1ccccc1,,[Na+].[OH-],,test
US04248622,CCOC(=O)c1c(F)ccc2c1C(=O)c1ccccc1-2>>O=C(O)c1c(F)ccc2c1C(=O)c1ccccc1-2,,O,,Cl,[Na+].[OH-],test
US20150111870A1,COc1nc2ccc(C(=O)C3CCN(C(=O)OC(C)(C)C)CC3)cc2c(Cl)c1CC1CCOCC1.Cc1ncc(Br)n1C>>COc1nc2ccc(C(O)(c3cncn3C)C3CCN(C(=O)OC(C)(C)C)CC3)cc2c(Cl)c1CC1CCOCC1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20080058340A1,COCCO.O=[N+]([O-])c1c(O)cc(F)c(F)c1F>>COCCOc1cc(F)c(F)c(F)c1[N+](=O)[O-],,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080161328A1,Cc1nc2cccc(CN)c2c(=O)n1C1CCC(=O)NC1=O.O=C(Cl)c1ccc(OC(F)(F)F)cc1>>Cc1nc2cccc(CNC(=O)c3ccc(OC(F)(F)F)cc3)c2c(=O)n1C1CCC(=O)NC1=O,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US05741926,O=C(CNc1ccccc1F)Nc1ccccc1C(=O)O>>O=C(O)c1ccccc1NCCNc1ccccc1F,,C1CCOC1,,B,,test
US20060094767A1,C=C(CC)COCOC.O=C(OO)c1cccc(Cl)c1>>CCC1(COCOC)CO1,,ClCCl,,,,test
US20130029962A1,Nc1ccccc1.O=C(O)c1ccc(Br)cn1>>NC(=O)c1ccccn1,,C1CCOC1,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20020086871A1,BrBr.c1cnc2nc(N3CCN4CCC3CC4)oc2c1>>Brc1cnc2nc(N3CCN4CCC3CC4)oc2c1,,CC(=O)O,O,CC(=O)[O-].[Na+],,test
US04229464,CCOC(=O)c1cc2c(O)cc(C)cc2[nH]1.ClCC1CO1>>CCOC(=O)c1cc2c(OCC3CO3)cc(C)cc2[nH]1,C1CCNCC1,,,,,test
US20070191293A1,CC(C)(C)OC(=O)N[C@H]1CCc2ccccc21.CI>>CN(C(=O)OC(C)(C)C)[C@H]1CCc2ccccc21,,C1CCOC1,,[H-].[Na+],,test
US20150353533A1,CC(C)(C)OC(=O)N[C@H]1CNc2ccccc2NC1=O.CI.CN(C)C=O>>CN1C[C@H](NC(=O)OC(C)(C)C)C(=O)N(C)c2ccccc21,,CCOC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140045822A1,CC(C)(C)OC(=O)Nc1ccc2c(c1)C1(CC1c1ccc3c(I)n[nH]c3c1)C(=O)N2.CN1CCN(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1>>CN1CCN(c2ccc(-c3n[nH]c4cc(C5CC56C(=O)Nc5ccc(N)cc56)ccc34)cc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040158067A1,CCc1cccc(CC)c1-c1cc(OC)c(C(=O)OC)cn1.O=P(Cl)(Cl)Cl>>CCc1cccc(CC)c1-c1cc(Cl)c(C(=O)OC)cn1,,CN(C)C=O,,,,test
US20120010241A1,Cc1nn(-c2ccc(C#N)c(NCC(C)(C)O)c2)c2cccc(-c3nc4ccc(F)cc4[nH]3)c12.OO>>Cc1nn(-c2ccc(C(N)=O)c(NCC(C)(C)O)c2)c2cccc(-c3nc4ccc(F)cc4[nH]3)c12,,CS(C)=O,O,CCO,[Na+].[OH-],test
US20090176786A1,CI.CN(C(=O)NC(=O)c1c(F)cccc1Cl)c1ccc(SC(F)(F)C(F)F)cc1F>>CN(C(=O)c1c(F)cccc1Cl)C(=O)N(C)c1ccc(SC(F)(F)C(F)F)cc1F,,CN1CCCC1=O,O,[H-].[Na+],[Cl-].[NH4+],test
US20020091273A1,COc1cc2cc3c(Cl)ncnc3cc2cc1OCCN1CCOCC1.Cl.Nc1cccc(Br)c1>>COc1cc2cc3c(Nc4cccc(Br)c4)ncnc3cc2cc1OCCN1CCOCC1.Cl.Cl,,CC(C)O,,c1ccncc1,,test
US20160229865A1,C#CC(=O)O.Cc1cc(Nc2nc(N[C@@H]3CCCNC3)c3cccn3n2)sn1>>C#CC(=O)N1CCC[C@@H](Nc2nc(Nc3cc(C)ns3)nn3cccc23)C1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US08580710B2,CC(=O)OCCN=C=S.Cc1cc(C)cc(CC(N)c2cccc3c2CCCC3)c1>>CC(=O)OCCNC(=S)NC(Cc1cc(C)cc(C)c1)c1cccc2c1CCCC2,,ClC(Cl)Cl,,,,test
US20070049574A1,COC(=O)CC(C)=O.NNc1ccc(F)cc1>>CC1=NN(c2ccc(F)cc2)C(=O)C1,,CC(=O)O,,,,test
US20030078249A1,COC(=O)c1cc(Cl)c(OCC2CCCN2C(=O)OC(C)(C)C)c(Cl)c1>>COC(=O)c1cc(Cl)c(OCC2CCCN2)c(Cl)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05410630,CN(C)c1ccc(C=O)cc1.CS(=O)(=O)CC#N>>CN(C)c1ccc(C=C(C#N)S(C)(=O)=O)cc1,,CCO,,C,O=C[O-].[NH4+],test
US20160193218A1,COc1ccc(-c2nc3cc(OC)cc(OC)c3c(=O)[nH]2)c(SC2CCN(C)CC2)c1.O>>COc1ccc(-c2nc3cc(OC)cc(OC)c3c(=O)[nH]2)c(S(=O)C2CCN(C)CC2)c1,,CO,,,,test
US20120270838A1,CSC1=NC2(CCN(C(=O)OC(C)(C)C)CC2)C(=O)N1.Nc1cccc(C(F)(F)F)c1>>CC(C)(C)OC(=O)N1CCC2(CC1)N=C(Nc1cccc(C(F)(F)F)c1)NC2=O,,CC(=O)N(C)C,,CC(=O)O,O=C([O-])O.[Na+],test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(C2CCOCC2)c2nc(C)nn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(C2CCOCC2)c2nc(C)nn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20070112068A1,C#CCBr.N#CC(C#N)CC(F)(F)C(F)(F)C(F)(F)C(F)F>>C#CCC(C#N)(C#N)CC(F)(F)C(F)(F)C(F)(F)C(F)F,,COCCOC,,Cl,O=C([O-])[O-].[K+].[K+],test
US20120214784A1,CCOC(=O)c1nn(-c2ccccc2F)cc1CN1CCC2(CC1)OCC(F)(F)c1cc(Cl)sc12>>OCc1nn(-c2ccccc2F)cc1CN1CCC2(CC1)OCC(F)(F)c1cc(Cl)sc12,,C1CCOC1,CCO,[BH4-].[Li+],,test
US20020103229A1,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].N#Cc1ccc2c(c1)c(CCc1ccccc1)nn2C1CCCCO1>>c1ccc(CCc2n[nH]c3ccc(-c4nn[nH]n4)cc23)cc1,,Cc1ccccc1,,,,test
US20160243100A1,COc1ccc(S(=O)(=O)C(C)(F)C2CCN(C(=O)OC(C)(C)C)CC2)cn1.Cl>>COc1ccc(S(=O)(=O)C(C)(F)C2CCNCC2)cn1.Cl,,C1COCCO1,,,,test
US05587392,Cn1nnc2ccc(Cc3ccc(Cl)cc3CO)cc21.O=S(Cl)Cl>>Cn1nnc2ccc(Cc3ccc(Cl)cc3CCl)cc21,,ClCCl,,c1ccncc1,,test
US20150099730A1,COC(=O)N1CCC2(CC1)N=C(c1ccc(Br)cc1)N(C[C@@H]1CCN(C(=O)C3CC3)C1)C2=O.OB(O)c1ccc2occc2c1>>COC(=O)N1CCC2(CC1)N=C(c1ccc(-c3ccc4occc4c3)cc1)N(C[C@@H]1CCN(C(=O)C3CC3)C1)C2=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,,,test
US20090232747A1,CC(C)S.CCOC(=O)C(C)(C)Br>>CCOC(=O)C(C)(C)SC(C)C,,CCO,,[K+].[OH-],,test
US04273782,CC(C)c1c(Cc2ncc[nH]2)c2ccccc2n1CCC#N.[OH-]>>CC(C)c1c(Cc2ncc[nH]2)c2ccccc2n1CCC(N)=O,,Cl,,CCO,,test
US20130116229A1,CCOC(=O)CC(=O)OCC.COc1cc(C(=O)O)c(Br)cc1[N+](=O)[O-]>>CCOC(=O)C(C(=O)OCC)c1cc([N+](=O)[O-])c(OC)cc1C(=O)O,[Cu]Br,O,,[Na],,test
US04311787,NC(=O)C1=NN(CC(F)(F)F)C(=O)C1.O=Cc1ccc(O)cc1>>NC(=O)C1=NN(CC(F)(F)F)C(=O)C1=Cc1ccc(O)cc1,,COCCO,,,,test
US05858995,Cc1oc2c(N3C(=O)c4c(Cl)ccc(Cl)c4C3=O)cccc2c1C.[OH-]>>Cc1oc2c(NC(=O)c3c(Cl)ccc(Cl)c3C(=O)O)cccc2c1C,,CO,,Cl,,test
US20140107139A1,O=[N+]([O-])c1ccc(F)cc1.Oc1ccc2c(c1)COC2>>O=[N+]([O-])c1ccc(Oc2ccc3c(c2)COC3)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05276039,CC(=O)OC(C)=O.O=C1CCCc2sccc21>>C=C1CCc2sccc2C1=O,,O,,,,test
US20100311748A1,Cc1ccc(-c2ncc[nH]2)cc1NC(=O)c1ccc(O)cc1.Cc1ccc(S(=O)(=O)OCc2cccc(Br)n2)cc1>>Cc1ccc(-c2ncc[nH]2)cc1NC(=O)c1ccc(OCc2cccc(Br)n2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04810805,CCCCCC(=O)CP(=O)(OC)OC.O=C1CCC(=O)N1Cl>>CCCCCC(=O)C(Cl)P(=O)(OC)OC,,COCCOC,,[H-].[Na+],[Cl-].[NH4+],test
US20080269294A1,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(C2CCNCC2)cc1.O=Cc1cc[nH]n1>>Nc1ccccc1NC(=O)c1ccc(C2CCN(Cc3cc[nH]n3)CC2)cc1,,C1COCCO1,ClCCl,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20150166716A1,Br.O=C(c1ccccc1)c1ccc(OCC2(CO)COC2)cc1>>O=C(c1ccccc1)c1ccc(OCC(CO)(CO)CBr)cc1,,O,,,,test
US20160002251A1,CCOC(=O)C(C)(C)Br.CNN.O=Cc1cccc(F)c1F>>CCOC(=O)C(C)(C)N(C)N=Cc1cccc(F)c1F,,C1CCOC1,CO,CCN(C(C)C)C(C)C,,test
US20140302539A1,CCOC(=O)C(OCC)OCC.Fc1ccc(C[Mg]Cl)cc1>>CCOC(OCC)C(=O)Cc1ccc(F)cc1,,C1CCOC1,,CCOCC,[Cl-].[NH4+],test
US20070078135A1,C1CSCCN1.Clc1cncc(Cl)n1>>Clc1cncc(N2CCSCC2)n1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080045562A1,CCOC(=O)c1cncc2c(COc3cccc(N)c3)csc12.O=C(Cl)c1ccccc1>>CCOC(=O)c1cncc2c(COc3cccc(NC(=O)c4ccccc4)c3)csc12,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US04824968,CC1Sc2sc(S(N)(=O)=O)cc2C(=O)C1C.CCN>>CCNC1CC(C)(C)Sc2sc(S(N)(=O)=O)cc21,Cl[Ti](Cl)(Cl)Cl,c1ccccc1,,C1CCOC1,[BH4-].[Na+],test
US04920219,C=CCc1c(N)c(Cl)cc(C(=O)OC)c1O.CI>>C=CCc1c(N)c(Cl)cc(C(=O)OC)c1OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150344473A1,Nc1ncnc(Cl)c1N.O=C(O)c1ccc(C2CCN(CC(F)(F)F)CC2)cc1>>FC(F)(F)CN1CCC(c2ccc(-c3nc4c(Cl)ncnc4[nH]3)cc2)CC1,,O=P(Cl)(Cl)Cl,,,,test
US20130310405A1,CC(C)(C)OC(=O)NC1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CCC1.Clc1nc2c3cc(Br)ccc3nn2cc1-c1ccccc1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c5cc(Br)ccc5nn4cc3-c3ccccc3)cc2)CCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20050033081A1,CON(C)C(=O)C=Cc1ccccc1C(F)(F)F.[Li]C>>CC(=O)C=Cc1ccccc1C(F)(F)F,,C1CCOC1,CCOCC,CCOC(C)=O,O,test
US20110028466A1,CCOCCl.Oc1cnc(Cl)nc1>>CCOCOc1cnc(Cl)nc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100273806A1,COC(=O)c1cc(O)cc(C#N)c1.OCCF>>COC(=O)c1cc(C#N)cc(OCCF)c1,,ClCCl,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110319393A1,CC(C)(C)OC(=O)N1CCC(Nc2ccc(C(F)(F)F)cn2)CC1.Cl.ClCCl>>Cl.Cl.FC(F)(F)c1ccc(NC2CCNCC2)nc1,,C1COCCO1,ClCCl,O=C(O)C(F)(F)F,,test
US20040082542A1,CCCCNc1cc(OCCN2CCCC2)ccc1N.O=Cc1ccc(OCCc2ccc(Cl)cc2)cc1>>CCCCn1c(-c2ccc(OCCc3ccc(Cl)cc3)cc2)nc2ccc(OCCN3CCCC3)cc21,,CCO,,,,test
US20040006099A1,CI.NC(=S)N1CCc2ccc(OCC3CCN(c4ccncc4)CC3)cc2C1>>CSC(=N)N1CCc2ccc(OCC3CCN(c4ccncc4)CC3)cc2C1,,CO,,CCO,Cl,test
US20150322024A1,NCCc1c[nH]cn1.O=C(/C=C/c1ccccc1F)ON1C(=O)CCC1=O>>O=C(/C=C/c1ccccc1F)NCCc1c[nH]cn1,,C1COCCO1,,O=C([O-])O.[Na+],,test
US20060111338A1,O=C(NC1Cc2cccnc2C(O)C1)OCc1ccccc1>>O=C(NC1CC(=O)c2ncccc2C1)OCc1ccccc1,,CCOC(C)=O,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20130158009A1,Cc1nnc(-c2ccc(O[C@H]3CCN(C4CCN(C(=O)OC(C)(C)C)CC4)C3=O)c(F)c2)o1.O=C(O)C(F)(F)F>>Cc1nnc(-c2ccc(O[C@H]3CCN(C4CCNCC4)C3=O)c(F)c2)o1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20090030082A1,COC(=O)Cc1cccc(OCCCNCC(c2ccccc2)c2ccccc2)c1.Fc1c(CBr)cccc1C(F)(F)F>>COC(=O)Cc1cccc(OCCCN(Cc2cccc(C(F)(F)F)c2F)CC(c2ccccc2)c2ccccc2)c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20140296245A1,COC(=O)C1=C(c2ccc(Cl)cc2)CCC2(C1)OCCO2>>COC(=O)[C@@H]1CC2(CC[C@H]1c1ccc(Cl)cc1)OCCO2,,CO,ClCCl,[Mg],,test
US05138090,CC(C)c1cc(C(C)C)c(CO)cc1CO.CI>>COCc1cc(CO)c(C(C)C)cc1C(C)C,,C1CCOC1,,Cl,[H-].[Na+],test
US20140378483A1,C=c1nc(-c2ccccc2)oc(=O)/c1=C/C(=C\C)C(=O)c1c(C)c(Br)c2ccccn12>>Cc1c(Br)c2ccccn2c1C(=O)c1ccc(N)c(C(=O)O)c1,,CN1CCCC1=O,O,Cl,[K+].[OH-],test
US20130267495A1,NCc1cncc(Br)c1.O=CC1CCCC1>>Brc1cncc(CNCC2CCCC2)c1,,CO,,[BH3-]C#N.[Na+],,test
US20160075713A1,Cc1ccc(S(=O)(=O)n2ccc3c(NC4CCN(CC(F)(F)c5ncc(C(F)(F)F)cc5F)CC4)ncnc32)cc1>>Fc1cc(C(F)(F)F)cnc1C(F)(F)CN1CCC(Nc2ncnc3[nH]ccc23)CC1,,C1CCOC1,,[Na+].[OH-],,test
US20130281414A1,O=C1CSC(=O)N1.O=Cc1ccc(OCC(O)c2ccccc2)cc1>>O=C1NC(=O)C(=Cc2ccc(OCC(O)c3ccccc3)cc2)S1,CC(=O)O,CCO,,C1CCNCC1,,test
US06919328B1,O=C1Nc2ccccc2Oc2ccc([N+](=O)[O-])cc21>>Nc1ccc2c(c1)C(=O)Nc1ccccc1O2,,CCO,,Cl[Sn]Cl,,test
US20130184284A1,N.N#Cc1ccc(N2CCC[C@H](N[C@@H]3CCCC[C@H]3Nc3cc(/C=C\C(=O)O)ccn3)C2)cc1>>N#Cc1ccc(N2CCC[C@H](N[C@@H]3CCCC[C@H]3Nc3cc(/C=C\C(N)=O)ccn3)C2)cc1,,C1CCOC1,CO,CC(C)COC(=O)Cl,CCN(CC)CC,test
US20110077235A1,Cc1cc2nc(N)cc(-c3ccccc3)n2n1.O=C(Cl)C1CC1c1ccncc1>>Cc1cc2nc(NC(=O)C3CC3c3ccncc3)cc(-c3ccccc3)n2n1,,c1ccncc1,,,,test
US20040162435A1,CN1C(=S)CC[C@@H]1CC#N>>CN1CCC[C@@H]1CC#N,[Ni],CCO,,,,test
US04511568,CCC(C(=O)Cl)C(=O)Cl.CCCNCC(=O)OCC.CCOCC>>CCCN(CC(=O)OCC)C(=O)CC(=O)OCC,,O,,O=C([O-])[O-].[K+].[K+],,test
US20110003988A1,Cc1noc(-c2ccc([C@H]3CN(C(=O)OC(C)(C)C)CCO3)cc2)n1.Cl>>Cc1noc(-c2ccc([C@H]3CNCCO3)cc2)n1.Cl,,CCOC(C)=O,,,,test
US05075301,C=O.N#CC(C#N)=C1NCCN1CCNCc1ccc(CN2CCCCC2)o1>>CN(CCN1CCNC1=C(C#N)C#N)Cc1ccc(CN2CCCCC2)o1,,CC#N,,CC(=O)O,[BH3-]C#N.[Na+],test
US20100105904A1,COc1cc(NC(=O)OC(C)(C)C)ccc1-n1ccnc1>>COc1cc(N)ccc1-n1ccnc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020052322A1,CCOC(=O)[C@@H](N)Cc1ccc(O)cc1.C[C@H](NC(=O)Cc1cccc([N+](=O)[O-])c1)C(=O)O>>CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)Cc1cccc([N+](=O)[O-])c1,,CCOC(C)=O,,,,test
US20160016908A1,COc1cccc(N[C@H]2c3cc(N4CCN(C(=O)OC(C)(C)C)[C@@H](C)C4)ccc3N(C(C)=O)[C@@H](C3CC3)[C@@H]2C)n1>>COc1cccc(N[C@H]2c3cc(N4CCN[C@@H](C)C4)ccc3N(C(C)=O)[C@@H](C3CC3)[C@@H]2C)n1,,CC#N,,[I-].[Na+],,test
US04273704,CSCC[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)NCC(=O)O.N[C@@H](Cc1ccccc1)C(=O)C1C2CC3CC(C2)CC1(N)C3>>CSCC[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)C1C2CC3CC(C2)CC1(N)C3,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20040138461A1,CCC(=O)N(c1ccccc1)C1(COC)CCN(CCn2nnn(CC)c2=O)CC1>>CCC(=O)N(c1ccccc1)C1(COC)CCN(CCn2nnn(CC)c2=O)CC1,,O,,Cl,,test
US20110009454A1,Cc1ccc(C(=O)O)c(N)n1.NCc1cccc(Oc2cccc(OC(F)(F)F)c2)c1>>Cc1ccc(C(=O)NCc2cccc(Oc3cccc(OC(F)(F)F)c3)c2)c(N)n1,,CN(C)C=O,O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20020165236A1,O=[N+]([O-])c1ccc(S(=O)(=O)NCc2ccccc2)cc1>>Nc1ccc(S(=O)(=O)NCc2ccccc2)cc1,[Pd],CCO,,,,test
US20020161006A1,COC(=O)CCc1ccccc1O.OCCNC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)CCc1ccccc1OCCNC(c1ccccc1)(c1ccccc1)c1ccccc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090163524A1,CC(C)(C)OC(=O)NC1(C(=O)NC(CCCO)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1>>NC1(C(=O)NC(CCCO)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1,,CO,,O=C(O)C(F)(F)F,,test
US20100063038A1,CC(C)(C)OC(=O)N1CCOC(C(=O)c2cc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)c(F)c3)c3c(N)ncnn23)C1>>Nc1ncnn2c(C(=O)C3CNCCO3)cc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)c(F)c3)c12,,C1COCCO1,,Cl,,test
US04385062,CC(=O)SC1CCCC1C(=O)N1CCC[C@H]1C(=O)O>>O=C(O)[C@@H]1CCCN1C(=O)C1CCCC1S,,CO,,N,,test
US20130231328A1,CC(C)(C)OC(=O)NC1CCC(O)CC1.CCOC(=O)C[C@@H]1CCCc2sc3ncnc(Cl)c3c21>>CCOC(=O)C[C@@H]1CCCc2sc3ncnc(OC4CCC(NC(=O)OC(C)(C)C)CC4)c3c21,,C1CCOC1,,[H-].[Na+],,test
US20030065174A1,C=CC(O)CCN(C)C(=O)OC(C)(C)C.N#Cc1cc(F)c(Cl)cc1F>>C=CC(CCN(C)C(=O)OC(C)(C)C)Oc1cc(Cl)c(F)cc1C#N,,CN(C)C=O,,,,test
US20130059832A1,Cc1ccc(-c2noc(N3CCC3)n2)cc1[N+](=O)[O-].O=C(O)c1cnc2ccccn12>>Cc1ccc(-c2noc(N3CCC3)n2)cc1NC(=O)c1cnc2ccccn12,,ClCCl,c1ccncc1,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20120316147A1,CC(C)(C)OC(=O)N[C@@H](CC1CC1)C(N)=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)OC(=O)N[C@@H](CC1CC1)C(N)=S,,Cc1ccccc1,,,,test
US04906634,CCN(CC)CCN.Cl.O=[N+]([O-])c1ccc(F)cc1>>CCN(CC)CCNc1ccc([N+](=O)[O-])cc1.Cl,,ClCCl,,,,test
US20090093485A1,Cc1cc(C)c(S(=O)(=O)N[C@@H](C)COS(=O)(=O)c2c(C)cc(C)cc2C)c(C)c1.NC(=O)c1cc(F)ccc1O>>Cc1cc(C)c(S(=O)(=O)N[C@@H](C)COc2ccc(F)cc2C(N)=O)c(C)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080081910A1,CCOC(=O)C1CCC(Br)C(O)C1>>CCOC(=O)C1CCC(Br)C(=O)C1,,CC(C)=O,O,CC(C)O,,test
US05202344,C=CC(=O)OC(C)(C)C.Nc1ccccc1>>CC(C)(C)OC(=O)CCNc1ccccc1,,c1ccccc1,,Cl[Sn](Cl)(Cl)Cl,,test
US20160016948A1,CC(C)(CCOC1CCCCO1)n1c(=O)[nH]c2cnc(Br)cc21>>CC(C)(CCO)n1c(=O)[nH]c2cnc(Br)cc21,,CO,Cl,O=C([O-])O.[Na+],,test
US20110009454A1,Cc1ccc(C(=O)O)c(N)n1.NCc1cccc(Oc2ccc(OC(F)(F)F)cc2)c1>>Cc1ccc(C(=O)NCc2cccc(Oc3ccc(OC(F)(F)F)cc3)c2)c(N)n1,,CN(C)C=O,O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20050107325A1,COc1ccc(C(OC(c2ccccc2)C2CN(C(=O)CCCCCNC(=O)OCc3ccccc3)CC2O)c2ccc(OC)cc2)cc1>>COc1ccc(C(OC(c2ccccc2)C2CN(C(=O)CCCCCN)CC2O)c2ccc(OC)cc2)cc1,,CO,,,,test
US05037961,CC(=O)c1cccc(N)c1>>C=Cc1cccc(N)c1,,CC(C)O,,Cl,[BH4-].[Na+],test
US20090197871A1,COc1c(Br)cccc1CN1C(=O)c2ccccc2C1=O>>COc1c(Br)cccc1CN,,CCO,,NN,O,test
US20040048916A1,CC(C)(C)c1ccc2c(c1)C(=O)OC2=O.CC(C)CN>>CC(C)CN1C(=O)c2ccc(C(C)(C)C)cc2C1=O,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120010188A1,Nc1ccc(Br)cn1.O=C(CBr)c1ccc(Br)cc1>>Br.Brc1ccc(-c2cn3cc(Br)ccc3n2)cc1,,CCO,,,,test
US20070197617A1,C[C@@H](c1ccccc1)[C@H](NC(=O)OC(C)(C)C)C(=O)O.Fc1nc(F)nc(F)n1>>CC(c1ccccc1)C(NC(=O)OC(C)(C)C)C(=O)F,,ClCCl,,c1ccncc1,,test
US20140206680A1,CCCC[Sn](Cl)(CCCC)CCCC.Ic1cc2n(c1)CCOC2>>CCCC[Sn](CCCC)(CCCC)c1cc2n(c1)CCOC2,,C1CCOC1,,[Li]CCCC,,test
US20080214448A1,CCOC(=O)CCCCc1cc(-c2cc(Cl)ccc2OC)on1>>CCOC(=O)CCCCc1cc(-c2cc(Cl)ccc2O)on1,,ClCCl,,BrB(Br)Br,,test
US20020086886A1,COC1CCOC(c2cccc(O)c2)C1.NS(=O)(=O)c1ccc(-c2oc(Cl)nc2-c2ccccc2)cc1>>COC1(c2cccc(Oc3nc(-c4ccccc4)c(-c4ccc(S(N)(=O)=O)cc4)o3)c2)CCOCC1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150266879A1,CC(C)(C)OC(=O)N[C@H](C(=O)N1c2ncccc2C[C@H]1C(=O)Nc1ccccc1)C1CCCCC1>>N[C@H](C(=O)N1c2ncccc2C[C@H]1C(=O)Nc1ccccc1)C1CCCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140163002A1,C=CC(C)C(=O)O.OCc1ccccc1>>C=CC(C)C(=O)OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05563162,CNC(=O)c1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4ccc(C)nc34)c2Cl)cc1.O=S(=O)(O)O>>CNC(=O)c1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4ccc(C)nc34)c2Cl)cc1.O=S(=O)(O)O,,CCO,,,,test
US20110152285A1,CCOC(=O)CN.COC1CC(c2ccccc2)C(OC)O1>>CCOC(=O)Cn1ccc(-c2ccccc2)c1,,CC(=O)O,O,Cl,CC(=O)[O-].[Na+],test
US20030096908A1,C=C(C)C(=O)OCCO.O=C(O)CCCc1c[nH]c2ccccc12>>C=C(C)C(=O)OCCO.O=C(O)CCCc1c[nH]c2ccccc12,,CCOC(C)=O,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20070197537A1,COC(=O)C1(C)CCN(c2ccc(F)cc2)C1=O>>CC1(C(=O)O)CCN(c2ccc(F)cc2)C1=O,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20060276505A1,NNc1cccc2ncccc12.O=C(Cl)C12CC3CC(CC(C3)C1)C2>>O=C(NNc1cccc2ncccc12)C12CC3CC(CC(C3)C1)C2,,C1CCOC1,,CCN(CC)CC,,test
US06326369B1,COc1c2c(c(OC)c(OC)c1OC)CC(CCCCCCCCI)C2.Oc1ccc(Cl)cc1>>COc1c2c(c(OC)c(OC)c1OC)CC(CCCCCCCCOc1ccc(Cl)cc1)C2,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04698093,CN.COC(=O)c1c(C(F)F)nc(C(F)(F)F)c(C(=O)n2cccn2)c1NC(C)C>>CNC(=O)c1c(C(F)(F)F)nc(C(F)F)c(C(=O)OC)c1NC(C)C,,CCOCC,,,,test
US20050148627A1,O=C(O)C1=Cc2cc(OC(F)(F)F)cc(C#Cc3ccccn3)c2OC1C(F)(F)F>>O=C(O)C1=Cc2cc(OC(F)(F)F)cc(CCc3ccccn3)c2OC1C(F)(F)F,[Pd],CC(=O)O,,,,test
US20100152183A1,CC(C)(C)OC(=O)N1CCNCC1.Fc1cc(-c2ccc(Cl)cc2)c(CBr)cn1>>CC(C)(C)OC(=O)N1CCN(Cc2cnc(F)cc2-c2ccc(Cl)cc2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070213331A1,CCCN(C)C(=O)c1cc(C=C(F)F)cc(C(=O)OCC)c1>>CCCN(C)C(=O)c1cc(C=C(F)F)cc(C(=O)O)c1,,C1CCOC1,,Cl,[Li+].[OH-],test
US20030055246A1,C=Cc1ccncc1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(CCc2ccncc2)CC1,,CCO,,CC(=O)O,,test
US20080004271A1,CCOC(=O)CC#N.N=C(N)NC1CC1.O=Cc1ccccc1Cl>>N#Cc1c(-c2ccccc2Cl)nc(NC2CC2)[nH]c1=O,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20040063944A1,O=C(c1ccc(Cl)cc1)c1ccc2ncc(C(=O)O)c(O)c2c1>>O=C(c1ccc(Cl)cc1)c1ccc2nccc(O)c2c1,,ClCCl,,c1ccc2ncccc2c1,,test
US20100152257A1,CO.Cc1noc(-c2ccc(-c3ccc(CC(=O)O)cc3)cc2)c1NC(=O)OC(C)c1ccccc1Cl>>COC(=O)Cc1ccc(-c2ccc(-c3onc(C)c3NC(=O)OC(C)c3ccccc3Cl)cc2)cc1,,CO,c1ccccc1,C[Si](C)(C)C=[N+]=[N-],,test
US04250096,Nc1ccc(C(=O)O)cc1.[N-]=[N+]=Nc1cccc2c1C(=O)OC2=O>>[N-]=[N+]=Nc1cccc2c1C(=O)N(c1ccc(C(=O)O)cc1)C2=O,,C1COCCO1,,CC(=O)OC(C)=O,,test
US20120058893A1,COC(=O)c1scnc1NS(=O)(=O)Cc1ccccc1I.O=S(=O)(OCC(F)F)C(F)(F)F>>COC(=O)c1scnc1N(CC(F)F)S(=O)(=O)Cc1ccccc1I,,CC#N,,CCN(C(C)C)C(C)C,,test
US20120157448A1,C1=C(N2CCOCC2)CCOC1.O=Cc1cc(Br)ccc1O>>OC1c2cc(Br)ccc2OC2(N3CCOCC3)CCOCC12,,Cc1ccccc1,,,,test
US20110028509A1,N#Cc1ccc(CNS(=O)(=O)c2ccc(Cl)cc2)cc1.O=C(Cl)c1ccccn1>>N#Cc1ccc(CN(C(=O)c2ccccn2)S(=O)(=O)c2ccc(Cl)cc2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20150166480A1,CCN(CC)S(F)(F)F.OC1(CN2CCC(COc3ccc(Br)cc3)CC2)CCC1>>FC1(CN2CCC(COc3ccc(Br)cc3)CC2)CCC1,,ClCCl,,O=C([O-])O.[Na+],,test
US04471119,CCCc1c2nc(C(=O)OC)cc(NC(=O)C(Cl)(Cl)Cl)c2cc2c(=O)cc(C(=O)OCC)oc12>>CCCc1c2nc(C(=O)OC)cc(N)c2cc2c(=O)cc(C(=O)OCC)oc12,,O=S(=O)(O)O,,N,,test
US20070254881A1,COc1ccc(-n2nc(C(=O)N3CCCN3)cc2-c2cc[nH]c2)cn1.C[Si](C)(C)N=C=O>>COc1ccc(-n2nc(C(=O)N3CCCN3C(N)=O)cc2-c2cc[nH]c2)cn1,,C1COCCO1,,CO,,test
US20090318439A1,Cc1cc(F)ccc1[N+](=O)[O-].O=c1[nH]ccc2occc12>>Cc1cc(-n2ccc3occc3c2=O)ccc1[N+](=O)[O-],,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100184740A1,COc1cccn(-c2c(C)cc(N3C[C@H](CNC(=O)c4ccc(Cl)s4)OC3=O)cc2C)c1=O>>Cc1cc(N2C[C@H](CNC(=O)c3ccc(Cl)s3)OC2=O)cc(C)c1-n1cccc(O)c1=O,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US05354839,O=[N+]([O-])c1cc(Oc2ccc(-c3ccc(Oc4cc([N+](=O)[O-])cc(C(F)(F)F)c4)cc3)cc2)cc(C(F)(F)F)c1>>Nc1cc(Oc2ccc(-c3ccc(Oc4cc(N)cc(C(F)(F)F)c4)cc3)cc2)cc(C(F)(F)F)c1,[Pd],COCCO,,[H][H],,test
US20130331374A1,CC1(C)C[C@H](Nc2nc(Cl)ncc2F)C[C@@H]2CCCN21.COc1cc(F)c(N)cc1-n1nnn(C)c1=O>>COc1cc(F)c(Nc2ncc(F)c(N[C@@H]3C[C@@H]4CCCN4C(C)(C)C3)n2)cc1-n1nnn(C)c1=O,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05849758,CSSC.Fc1cccc(-c2ccc(C(F)(F)F)cc2)n1>>CSc1ccc(-c2ccc(C(F)(F)F)cc2)nc1F,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20050026970A1,C=C[Sn](CCCC)(CCCC)CCCC.COC(=O)C1(F)C=C2C(=NCN2C)C=C1Nc1ccc(I)cc1F>>C=Cc1ccc(NC2=CC3=NCN(C)C3=CC2(F)C(=O)OC)c(F)c1,,C1COCCO1,,,,test
US05145857,CCOC(=N)CC(=O)OCC.CNC.Cl>>CCOC(=O)CC(=N)N(C)C.Cl,,CCO,,,,test
US20160009688A1,COC(=O)c1ccc(C)c(N)c1.O=C(Cl)c1ccc(Cl)nc1>>COC(=O)c1ccc(C)c(NC(=O)c2ccc(Cl)nc2)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150057443A1,O=C(CBr)C1(c2ccc(Cl)c(Cl)c2)CCC1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1CC(=O)C1(c2ccc(Cl)c(Cl)c2)CCC1,,CN(C)C=O,,[K],,test
US20080207897A1,NCc1ccc(B(O)O)cc1.O=C(Cl)C1CCCC1>>O=C(NCc1ccc(B(O)O)cc1)C1CCCC1,,ClCCl,,CCN(CC)CC,Cl,test
US05985896,ClCC#CCCl.Cn1nncc1-c1cc(CO[C@H]2CCCN[C@H]2c2ccccc2)c2occc2c1>>Cn1nncc1-c1cc(CO[C@H]2CCCN(CC#CCCl)[C@H]2c2ccccc2)c2occc2c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20130123338A1,CCOC(=O)CCCCCO.CS(=O)(=O)Cl>>CCOC(=O)CCCCCS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US06124283,CN1CCN(c2cccc3c2C[C@H](N)CC3)CC1.COc1ccc(C(=O)Cl)cc1>>COc1ccc(C(=O)N[C@@H]2CCc3cccc(N4CCN(C)CC4)c3C2)cc1,,ClCCl,,CCN(CC)CC,,test
US04474777,CI.C[C@@H]1N=C(c2ccccc2Cl)c2cc([N+](=O)[O-])ccc2NC1=O>>C[C@@H]1N=C(c2ccccc2Cl)c2cc([N+](=O)[O-])ccc2N(C)C1=O,,CC(C)=O,,CC(=O)O,O=C([O-])[O-].[K+].[K+],test
US20090023917A1,COc1ccc2c(Cc3ccc(OCCN4CCCCC4)cc3)c(OS(=O)(=O)C(F)(F)F)ccc2c1.OB(O)c1c(F)cccc1F>>COc1ccc2c(Cc3ccc(OCCN4CCCCC4)cc3)c(-c3c(F)cccc3F)ccc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20050131022A1,CC(=O)Cl.Nc1ccc([N+](=O)[O-])c(N2CCCCC2)c1>>CC(=O)Nc1ccc([N+](=O)[O-])c(N2CCCCC2)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
USRE036562,CCNC(=O)c1cccc([Si](C)(C)C)c1Cl.CSCCl>>CCN(CSC)C(=O)c1c(Cl)cccc1[Si](C)(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20120225867A1,C[C@H](N)Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1.O=C(O)c1nc2ccccc2[nH]1>>C[C@@H](Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1nc2ccccc2[nH]1,,CN(C)C=O,,,,test
US20050137395A1,C1CCNC1.COC(=O)c1c(C)oc2cc(Oc3ccnc4cc(OCCBr)ccc34)ccc12>>Cc1oc2cc(Oc3ccnc4cc(OCCN5CCCC5)ccc34)ccc2c1C(=O)O,,CN(C)C=O,,,,test
US20160046583A1,COc1ccccc1CN.O=C(O)c1ccc2cncc(-c3ccc(Cl)cc3)c2c1>>COc1ccccc1CNC(=O)c1ccc2cncc(-c3ccc(Cl)cc3)c2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20120232051A1,COC(OC)OC.Nc1cnccc1Br>>CNc1cnccc1Br,O=C(O)C(F)(F)F,,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20020077357A1,C1CCOC1.CCOC(C)=O.CSCCNCCC1CCCCC1.Cl.NCCN1CCCCC1.O=C(n1ccnc1)n1ccnc1>>CSCCN(CCC1CCCCC1)C(=O)NCCN1CCCCC1.Cl.NCC1CCN(C(=O)OCc2ccccc2)CC1,,C1CCOC1,,,,test
US20110009454A1,Cl.NO.O=Cc1cccc(Oc2ccccc2)c1>>Cl.NCc1cccc(Oc2ccccc2)c1,[Pd],CCO,O,Cl,[H][H],test
US20110086858A1,C=CCCBr.COC(=O)c1ccc(Nc2nc(NCc3ccc(O)cc3)nc(OCC(F)(F)F)n2)cc1>>C=CCCOc1ccc(CNc2nc(Nc3ccc(C(=O)OC)cc3)nc(OCC(F)(F)F)n2)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US05556977,COc1ccc(N2CCNCC2)cc1.Clc1ccncc1>>COc1ccc(N2CCN(c3ccncc3)CC2)cc1,,O,,Cl,N,test
US20060135552A1,CC(=O)CC(=O)C1CC1.COC(=O)c1ccc(C(=O)c2c(N)sc3c2CCCCC3)cc1>>COC(=O)c1ccc(-c2c(C(=O)C3CC3)c(C)nc3sc4c(c23)CCCCC4)cc1,O=S(=O)(O)O,CC(=O)O,,,,test
US20160024057A1,C[C@@H]1C[C@H](Cn2ncc3cc(-c4cnn(C5CCCCO5)c4)ccc32)CN1.O=C(Cl)CCc1ccccc1>>C[C@H]1C[C@@H](Cn2ncc3cc(-c4cnn(C5CCCCO5)c4)ccc32)CN1C(=O)CCc1ccccc1,,CCOC(C)=O,ClCCl,CCN(CC)CC,O=C([O-])O.[Na+],test
US05169862,CCCCCCCCCCCCCCC(CCC(=O)OCc1ccccc1)(C(=O)O)C(=O)O>>CCCCCCCCCCCCCCC(CCC(=O)OCc1ccccc1)C(=O)O,,CN(C)C=O,,,,test
US04230628,CCOC(=O)C=COC(=O)c1ccc(NCCCCCCCCCCCCCCCC(=O)OC)cc1>>CCOC(=O)CCOC(=O)c1ccc(NCCCCCCCCCCCCCCCC(=O)OC)cc1,[Pd],C1CCOC1,,[H][H],,test
US20120214735A1,COC(=O)Cc1ccc(S(=O)(=O)Cl)cc1.O=C1CCC(=O)N1Br>>COC(=O)C(Br)c1ccc(S(=O)(=O)Cl)cc1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US05658920,Cc1ccc(S(=O)(=O)Cl)cc1.OCCCc1ccccc1F>>Cc1ccc(S(=O)(=O)OCCCc2ccccc2F)cc1,,CCOCC,,c1ccncc1,,test
US20080167310A1,BrC(Br)(Br)Br.CC(C)(C)OC(=O)CCc1ccc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1CO>>CC(C)(C)OC(=O)CCc1ccc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1CBr,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20030087920A1,COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(-c2ccncc2)nc1OCC#CCO.O=C=Nc1ccccc1>>COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(-c2ccncc2)nc1OCC#CCOC(=O)Nc1ccccc1,CN(C)c1ccncc1,CCOC(C)=O,ClC(Cl)Cl,CN(C)C=O,,test
US20140303360A1,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21>>O=C(O)c1ccc(O)cc1,,ClCCl,,CCOC(C)=O,,test
US04594098,CP(C)(=O)C(O)C(=O)O.N>>CP(C)(=O)C(O)C(=O)[O-].[NH4+],,O,,,,test
US04749729,CO.O=C(O)c1ccc(O)cc1>>COC(=O)c1ccc(O)cc1,,O,,O=S(=O)(O)O,,test
US20040053908A1,COCCOc1cc2nccc(Oc3ccc(N)cc3)c2cc1C#N.Cc1cc(NC(=O)Oc2ccccc2)on1>>COCCOc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)no4)cc3)c2cc1C#N,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20060135483A1,CCOP(=O)(OCC)C(F)(F)c1ccc(CBr)cc1Br.CCOP(=O)(OCC)C(F)(F)c1ccc(CN(c2ccc(F)cc2)c2ncc(-c3ccc(C#N)cc3)o2)cc1Br.N#Cc1ccc(-c2cnc(Nc3ccc(F)cc3)o2)cc1.OO>>CCOP(=O)(OCC)C(F)(F)c1ccc(CN(c2ccc(F)cc2)c2ncc(-c3ccc(C#N)cc3)o2)cc1Br.CCOP(=O)(OCC)C(F)(F)c1ccc(CN(c2ccc(F)cc2)c2ncc(-c3ccc(C(N)=O)cc3)o2)cc1Br,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US04521430,COc1ccc([C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2O)cc1.O=C(O)c1ccc([N+](=O)[O-])c([N+](=O)[O-])c1>>COc1ccc([C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(=O)c2ccc([N+](=O)[O-])c([N+](=O)[O-])c2)cc1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20150166543A1,CC(C)(C)OC(=O)NCCN.CCc1cc(N)ccc1Cc1c[nH]c2ccccc12.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCc1cc(NC(=O)NCCNC(=O)OC(C)(C)C)ccc1Cc1c[nH]c2ccccc12,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20050075378A1,CC(C)(C)OC(=O)C=Cc1ccc(O)cc1C=NO>>CC(C)(C)OC(=O)CCc1ccc(O)cc1CN,[Pd],CCO,,[H][H],,test
US20090209765A1,Fc1cncc2ccccc12.O=S(=O)(O)O>>Fc1cncc2ccccc12.O=S(=O)(O)O,,CC(C)=O,,,,test
US20140221333A1,COC(=O)c1ccc(C(F)F)nc1.Cl>>COC(=O)C1CCC(C(F)F)NC1.Cl,O=[Pt]=O,CO,,[H][H],,test
US20160229853A1,CC(C)OC(=O)C1(C(=O)OC(C)C)CC(N)C1.O=C(Cl)OCc1ccccc1>>CC(C)OC(=O)C1(C(=O)OC(C)C)CC(NC(=O)OCc2ccccc2)C1,,ClCCl,,CCN(CC)CC,,test
US20050182040A1,Nc1cccc(OC(F)(F)F)c1.O=C1CCC(=O)N1Br>>Nc1ccc(Br)c(OC(F)(F)F)c1,,CN(C)C=O,,O,,test
US20160221972A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)CNCc1cc(C(=O)OC)ccc1[N+](=O)[O-]>>COC(=O)CN(Cc1cc(C(=O)OC)ccc1[N+](=O)[O-])C(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,,,test
US04579848,CC(=O)OC(C)=O.Cc1cnc(-c2cccc([N+](=O)[O-])c2)n2nc(N)nc12>>CC(=O)Nc1nc2c(C)cnc(-c3cccc([N+](=O)[O-])c3)n2n1,CN(C)c1ccncc1,,,c1ccncc1,,test
US20140221665A1,COc1ccc2nc(C#N)sc2c1>>N#Cc1nc2ccc(O)cc2s1,,Cl,,c1ccncc1,,test
US20060160794A1,Clc1ccccc1C1CCCN1.O=C(O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-n1cccc1>>O=C(c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-n1cccc1)N1CCCC1c1ccccc1Cl,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20060189650A1,COC(=O)COc1ccc(S(=O)(=O)CCC2CCN(CC[C@H](c3ccc(S(C)(=O)=O)cc3)c3cc(F)cc(F)c3)CC2)cc1>>CS(=O)(=O)c1ccc([C@@H](CCN2CCC(CCS(=O)(=O)c3ccc(OCC(=O)O)cc3)CC2)c2cc(F)cc(F)c2)cc1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20060264431A1,CNC.COC1=N[C@](CCBr)(CC2CC2)C(OC)=N[C@@H]1C(C)C>>COC1=N[C@](CCN(C)C)(CC2CC2)C(OC)=N[C@@H]1C(C)C,CN(C)c1ccncc1,,,C1CCOC1,,test
US20140142082A1,CCCCOC(=O)NS(=O)(=O)c1cc(-c2cn(S(=O)(=O)c3ccccc3Cl)c3ccccc23)n(CC2CCCCC2)c1C>>Cc1c(S(N)(=O)=O)cc(-c2cn(S(=O)(=O)c3ccccc3Cl)c3ccccc23)n1CC1CCCCC1,,CO,Cl,,,test
US05616601,CS(=O)(=O)c1ccc(N)cc1.N#Cc1ccc(F)cc1>>CS(=O)(=O)c1ccc(NC(=N)c2ccc(F)cc2)cc1,,Cc1ccccc1,ClC(Cl)Cl,C[Al](C)C,,test
US20100048648A1,CCI.O=C(O)c1cccs1>>CCc1ccc(C(=O)O)s1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US04927565,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C(=C[C@H](O)[C@@H](N)CC(C)C)CCOC1CCCCO1>>CCOC(=O)C(=C[C@H](O)[C@H](CC(C)C)NC(=O)OC(C)(C)C)CCOC1CCCCO1,,CN(C)C=O,,CCN(CC)CC,O,test
US20160002175A1,Cc1c(Cl)cccc1-c1cc(Cl)nc(N)n1.NCCc1ccc(S(N)(=O)=O)cc1>>Cc1c(Cl)cccc1-c1cc(NCCc2ccc(S(N)(=O)=O)cc2)nc(N)n1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US05571845,NS(=O)(=O)c1cc(Cl)c([N+](=O)[O-])cc1[N+](=O)[O-].OCCNCCO>>NS(=O)(=O)c1cc(N(CCO)CCO)c([N+](=O)[O-])cc1[N+](=O)[O-],,C1COCCO1,,,,test
US04666510,CC(=O)Cl.CCC(=O)C1=C(O)CC(c2c(C)cc(C)c(N)c2C)CC1=O>>CCC(=O)C1=C(O)CC(c2c(C)cc(C)c(NC(C)=O)c2C)CC1=O,,ClCCl,,O,c1ccncc1,test
US04410537,CCOC(=O)CCCCBr.O=Cc1c(O)cccc1OCc1ccccc1>>CCOC(=O)CCCCOc1cccc(OCc2ccccc2)c1C=O,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US05994378,CC(C)(C)c1csc(-c2cc3cc(O)ccc3o2)n1.CCCC(Oc1ccccc1CO)C(=O)OC(c1ccccc1)c1ccccc1>>CCCC(Oc1ccccc1COc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1)C(=O)OC(c1ccccc1)c1ccccc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160108036A1,CCOC(=O)c1cn(Cc2ccc(F)nc2)nc1C(F)(F)F>>O=C(O)c1cn(Cc2ccc(F)nc2)nc1C(F)(F)F,,C1CCOC1,,O,[Li+].[OH-],test
US20150087639A1,O=[N+]([O-])c1cc(F)c2c(c1)OCC1CCCN21>>Nc1cc(F)c2c(c1)OCC1CCCN21,[Pd],C1CCOC1,,,,test
US20030176454A1,Nc1cccc([N+](=O)[O-])c1.O=C(Cl)c1cccc(Br)c1F>>O=C(Nc1cccc([N+](=O)[O-])c1)c1cccc(Br)c1F,,ClCCl,,c1ccncc1,,test
US20150238601A1,C1COCCN1.CC1(C)OB(c2cccc(N)c2)OC1(C)C.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC1(C)OB(c2cccc(NC(=O)N3CCOCC3)c2)OC1(C)C,,C1CCOC1,,CCN(CC)CC,,test
US20070281932A1,CCOc1cc2ncc(C#N)c(O)c2cc1NC(C)=O.O=P(Cl)(Cl)Cl>>CCOc1cc2ncc(C#N)c(Cl)c2cc1NC(C)=O,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20100068783A1,C=CCBr.O=C(c1ccccc1)c1ccc(CBr)cc1.O=C(c1ccccc1)c1ccc(CO)cc1>>C=CCOCc1ccc(C(=O)c2ccccc2)cc1.O=C(c1ccccc1)c1ccc(CBr)cc1,,C1CCOC1,,[H-].[Na+],,test
US20150344480A1,Cn1nc(-c2ccc(F)cc2)cc1C1CCOCC1.O=C1CCC(=O)N1Br>>Cn1nc(-c2ccc(F)cc2)c(Br)c1C1CCOCC1,,ClCCl,,,,test
US20150104384A1,CCOC(=O)c1cnc2c(cnn2Cc2ccc(OC)cc2)c1>>O=C(O)c1cnc2[nH]ncc2c1,,O=C(O)C(F)(F)F,,,,test
US20130053382A1,CC(C)(C)OC(=O)NCC1CC=C(c2cc(F)ccc2NC(=O)c2csc(-c3cnn(COCC[Si](C)(C)C)c3)n2)CC1.Cl>>Cl.NCC1CC=C(c2cc(F)ccc2NC(=O)c2csc(-c3cn[nH]c3)n2)CC1,,C1COCCO1,,,,test
US20140057916A1,BrCc1ccccc1.Cc1[nH]cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)c1-c1cccc(C(F)(F)F)c1>>Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cn1Cc1ccccc1,,CN(C)C=O,CO,O=C([O-])[O-].[K+].[K+],,test
US05444067,CCCCI.CCCCc1ccc(S(=O)(=O)NC(C)(C)C)s1>>CC(C)Cc1ccc(S(=O)(=O)NC(C)(C)C)s1,,CCOC(C)=O,,,,test
US20120128686A1,CCN(C(C)C)C(C)C.CN(C)C=O.Cc1c(C(=O)O)sc2ncnc(Nc3cccnc3OC3CCOCC3)c12>>Cc1c(C(=O)NCCN)sc2ncnc(Nc3cccnc3OC3CCOCC3)c12,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20130237502A1,CC1(C)O[C@H](c2ccc(-c3ccc(C(NCc4ccccc4)C(F)(F)F)nc3)cc2)[C@H](CF)N1C(=O)C(F)F>>CC1(C)O[C@H](c2ccc(-c3ccc(C(N)C(F)(F)F)nc3)cc2)[C@H](CF)N1C(=O)C(F)F,[Pd],CO,,,,test
US20070032489A1,CCc1ccc(C)[nH]c1=O.O=C1CCC(=O)N1Br>>CCc1cc(Br)c(C)[nH]c1=O,,CO,,,,test
US20090215829A1,CS(=O)(=O)OC1CCN(Cc2ccc(F)cc2)C1.Oc1ccccc1Br>>Fc1ccc(CN2CCCC2Oc2ccccc2Br)cc1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20130281433A1,Cn1ncc2cc(-c3ccc(N)c(Br)n3)ccc21.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>Cn1ncc2cc(-c3ccc(NC(=O)C(F)(F)F)c(Br)n3)ccc21,CN(C)c1ccncc1,ClCCl,,,,test
US20150291595A1,Cc1ccn2nc([C@H](C)Nc3ncnc4c3c(Br)cn4COCC[Si](C)(C)C)n(-c3ccccc3)c(=O)c12.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cc1ccn2nc([C@H](C)Nc3ncnc4c3c(-c3cnn(C)c3)cn4COCC[Si](C)(C)C)n(-c3ccccc3)c(=O)c12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US20070265303A1,C=CCCCCCCBr.CC(C)(C)OC(=O)NNNC(=O)OC(C)(C)C>>C=CCCCCCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US04202824,CCCCCC=CCC=CCC(CC1OC(=O)C1CCCCCC)OC(=O)C(CC(N)=O)NC(C)=O>>CCCCCCCCCCC[C@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(N)=O)NC(C)=O,O=[Pt],CO,,[H][H],,test
US20100273739A1,Cl.NCCOc1ccc2c(c1)C(Cc1ccc(Cl)c(Cl)c1)C(N1CCCC1)CC2.O=S(=O)(Cl)C1CCC1>>Cl.O=S(=O)(NCCOc1ccc2c(c1)C(Cc1ccc(Cl)c(Cl)c1)C(N1CCCC1)CC2)C1CCC1,CN(C)c1ccncc1,ClCCl,,,,test
US20140057895A1,CCc1nn(C(=N)NOC(=O)C2CC(=O)C2)c2cc(F)ccc12>>CCc1nn(-c2noc(C3CC(=O)C3)n2)c2cc(F)ccc12,,CC(=O)O,,,,test
US05547962,Cc1c(F)c(F)cc(C(=O)O)c1F.O=[N+]([O-])O>>Cc1c(F)c(F)c([N+](=O)[O-])c(C(=O)O)c1F,,O=S(=O)(O)O,,,,test
US20140066424A1,CN1CCNCC1.Cc1nc(-c2ncc(-c3ccc(OC(F)(F)F)cc3)o2)nn1Cc1ccnc(Cl)c1>>Cc1nc(-c2ncc(-c3ccc(OC(F)(F)F)cc3)o2)nn1Cc1ccnc(N2CCN(C)CC2)c1,,CS(C)=O,,,,test
US04536588,CC(CO)(CO)CO.Cc1ccc(S(=O)(=O)O)cc1.Cc1ccccc1.O>>CC(C)(C=O)CO.CC(CO)(CO)CO,,O,,,,test
US20040147543A1,CC(C)Cn1cnc2c(N)nc3ccc(C=Cc4ccccc4)cc3c21>>CC(C)Cn1cnc2c(N)nc3ccc(CCc4ccccc4)cc3c21,[Pd],CCO,,,,test
US20100204272A1,CC(C)(C)OC(=O)N1CCC(Nc2cc(C#N)ccc2O)CC1.ClCCl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>C=C1Oc2ccc(C#N)cc2N1C1CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20130345127A1,CC1(C)OC(NC23CC4CC2CC(C(N)=O)(C4)C3)=NS(=O)(=O)[C@@H]1c1ccc(C2CCNCC2)cc1.FC(F)(F)CCBr>>CC1(C)OC(NC23CC4CC2CC(C(N)=O)(C4)C3)=NS(=O)(=O)[C@@H]1c1ccc(C2CCN(CCC(F)(F)F)CC2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20110166103A1,COc1nc(N(C(=O)OC(C)(C)C)c2ccc(B3OC(C)(C)C(C)(C)O3)c(COC(C)=O)c2)ccc1C#N>>COc1nc(N(C(=O)OC(C)(C)C)c2ccc3c(c2)COB3O)ccc1C#N,,CO,,Cl,[Na+].[OH-],test
US20070249670A1,Cc1cccc(C)c1N=C=O.Nc1cc2ccccc2cc1C(=O)N(CC(=O)OCc1ccccc1)CC1CCCCC1>>Cc1cccc(C)c1NC(=O)Nc1cc2ccccc2cc1C(=O)N(CC(=O)OCc1ccccc1)CC1CCCCC1,,CN(C)C=O,,CCN(CC)CC,,test
US20140057931A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.O=[N+]([O-])c1ccc(O)cc1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.O=[N+]([O-])c1ccc(O)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100160303A1,NC(=O)c1ccc(C2=CCCCC2)c2c3c([nH]c12)CC(C(=O)NC1CCOCC1)CC3>>NC(=O)c1ccc(C2CCCCC2)c2c3c([nH]c12)CC(C(=O)NC1CCOCC1)CC3,[Pd],CO,,,,test
US20090088425A1,CCOC(=O)c1ccc(B(O)O)cc1.COc1ccc(C(C)C(O)(c2ccnc(I)c2)C(F)(F)F)c(Cl)c1>>CCOC(=O)c1ccc(-c2cc(C(O)(C(C)c3ccc(OC)cc3Cl)C(F)(F)F)ccn2)cc1,,C1COCCO1,CCOC(C)=O,O,O=C([O-])[O-].[Na+].[Na+],test
US20090082311A1,CC(=O)NC1(CCc2ccc(-c3ccc(Br)cc3F)cc2)COC(C)(C)OC1>>NC(CO)(CO)CCc1ccc(-c2ccc(Br)cc2F)cc1,,CCO,,Cl,,test
US20020193367A1,CC(C)(C)OC(=O)Nc1cc(N2CCCC2)c(F)cc1NC(=O)CC(=O)c1cccc(-n2nncc2COC2CCCCO2)c1>>O=C1CC(c2cccc(-n3nncc3CO)c2)=Nc2cc(N3CCCC3)c(F)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080214673A1,N[C@@H]1CCC[C@](O)(C#Cc2cccc(Cl)c2)C1.O=C(O)c1ccoc1>>O=C(N[C@@H]1CCC[C@](O)(C#Cc2cccc(Cl)c2)C1)c1ccoc1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,ClCCCl,test
US20080064704A1,CC1=C(C(=O)C2CC2)C(c2ccc(C#N)cc2)NC(=O)N1c1cccc(C(F)(F)F)c1.COC(=O)c1ccc(CCl)o1>>COC(=O)c1ccc(CN2C(=O)N(c3cccc(C(F)(F)F)c3)C(C)=C(C(=O)C3CC3)C2c2ccc(C#N)cc2)o1,,CN(C)C=O,CO,O=C([O-])[O-].[K+].[K+],,test
US20060211697A1,Cc1ccc(Oc2ccc(Br)cc2O)c(O)c1.OB(O)c1cccs1>>Cc1ccc(Oc2ccc(-c3cccs3)cc2O)c(O)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,O,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20160207949A1,CC(=S)OCCP(=O)(CCO)CCO.CSS(C)(=O)=O>>CS(=S)CCP(=O)(CCO)CCO,,CO,O,Cl,[Na+].[OH-],test
US20140364412A1,CC(C)(C)c1cc(N)n(-c2ccc(Cl)c(OCCCOC3CCCCO3)c2)n1.O=C(Cl)OCC(Cl)(Cl)Cl>>CC(C)(C)c1cc(NC(=O)OCC(Cl)(Cl)Cl)n(-c2ccc(Cl)c(OCCCOC3CCCCO3)c2)n1,,CCOC(C)=O,,[Na+].[OH-],,test
US20100048950A1,CC(C)C1CN1S(=O)(=O)c1c(Cl)cc(Cl)cc1Cl.CNc1ccccc1>>CC(C)C(CN(C)c1ccccc1)NS(=O)(=O)c1c(Cl)cc(Cl)cc1Cl,,C1CCOC1,,,,test
US20110294776A1,CS(=O)(=O)Cl.Nc1ncnn2c(C3CCCNC3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12>>CS(=O)(=O)N1CCCC(c2cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c3c(N)ncnn23)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20060205715A1,COc1ccc2c(c1C)CCC2=O>>Cc1c(O)ccc2c1CCC2=O,,ClCCl,,BrB(Br)Br,,test
US05939439,COC(=O)c1ccc(C#N)c(OCCCCc2ccccc2)c1>>N#Cc1ccc(CO)cc1OCCCCc1ccccc1,,C1CCOC1,,[BH4-].[Li+],,test
US20120230951A1,CCOC(=O)[C@H]1CC(=O)C2c3c(ccn3C1)CC[C@@H]2NC(=O)OC.O=C1CCC(=O)N1Br>>CCOC(=O)[C@H]1CC(=O)C2c3c(cc(Br)n3C1)CC[C@@H]2NC(=O)OC,,CN(C)C=O,,,,test
US05212195,CCCCC(=O)N(C)OC.Cc1cccnc1NC(=O)OC(C)(C)C>>CCCCC(=O)Cc1cccnc1NC(=O)OC(C)(C)C,,C1CCOC1,CCOCC,[Li]C(C)CC,,test
US20090275578A1,COC(=O)c1ccccc1CBr.NCc1cccc(Oc2ccccc2)c1>>O=C1c2ccccc2CN1Cc1cccc(Oc2ccccc2)c1,,CCCCCC,Cc1ccccc1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20040171881A1,COC(=O)c1ccc(O)c([N+](=O)[O-])c1.ClI>>COC(=O)c1cc(I)c(O)c([N+](=O)[O-])c1,,CC(=O)O,,O,,test
US20020028832A1,CCCCCCCCNC(=O)N1CCC(Nc2ccc(CCNC[C@H](O)COc3ccnc(/N=N/c4ccc([N+](=O)[O-])cc4)c3)cc2)CC1>>CCCCCCCCNC(=O)N1CCC(Nc2ccc(CCNC[C@H](O)COc3ccc(N)nc3)cc2)CC1,[Pd],,,CCO,[H][H],test
US20020045759A1,CC(C)(C)OC(=O)NCCS(=O)(=O)c1ccccc1.Cl>>Cl.NCCS(=O)(=O)c1ccccc1,,CCOC(C)=O,,,,test
US20020037888A1,C=CC[Si](C)(C)C.COc1cccc(C2(O)OCCN(C)C2=O)c1>>C=CCC1(c2cccc(OC)c2)OCCN(C)C1=O,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20030166717A1,CCCC(CCC)S(=O)(=O)CC(NC(=O)c1ccc(OC)cc1)C(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CN(Cc1cccc(CC)c1)C(=O)OC(C)(C)C.Cl>>CCCC(CCC)S(=O)(=O)CC(NC(=O)c1ccc(OC)cc1)C(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNCc1cccc(CC)c1.Cl,,C1COCCO1,,,,test
US20140206680A1,CCOC(=O)/C=C/CBr.O=Cc1cc(Br)c[nH]1>>CCOC(=O)c1ccn2cc(Br)cc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04761420,C1=COCCC1.O=C(O)C(=O)O.OCCc1ccc(O)cc1>>O=C(O)C(=O)O.Oc1ccc(CCOC2CCCCO2)cc1,,CC(C)=O,,O=S(=O)([O-])[O-].[Na+].[Na+],,test
US20120058989A1,CCOC(=O)c1cn(C2CC2)c2c(C#CC[C@H](CCC(=O)OC(C)(C)C)NC(=O)OCc3ccccc3)c(F)c(F)cc2c1=O>>CCOC(=O)c1cn(C2CC2)c2c(/C=C\C[C@@H](N)CCC(=O)OC(C)(C)C)c(F)c(F)cc2c1=O,CCN(CC)CC,CCO,,,,test
US20030207868A1,CC(=O)OCC(=O)Cl.N#Cc1ccc(NCCCCF)c(N)c1>>CC(=O)OCC(=O)Nc1cc(C#N)ccc1NCCCCF,,ClCCl,,CCN(CC)CC,,test
US20130004420A1,COCOC(c1cc(C)ccc1I)(C(F)(F)F)C(F)(F)F.O=C1CCC(=O)N1Br>>COCOC(c1cc(CBr)ccc1I)(C(F)(F)F)C(F)(F)F,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20040180925A1,CC(C)(C)OC(=O)NCCN.O=C(Cl)c1cnc2ccccc2n1>>NCCNC(=O)c1cnc2ccccc2n1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20130143892A1,CS(=O)(=O)c1ccc(F)c(F)c1.O=C(O)c1c[nH]cn1>>CS(=O)(=O)c1ccc(-n2cnc(C(=O)O)c2)c(F)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20160039811A1,CC(C)C(n1ccc(O)c(C#N)c1=O)C(F)(F)F.CI>>COc1ccn(C(C(C)C)C(F)(F)F)c(=O)c1C#N,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04550107,CN(C)CC1CCCCN1.O=C1Nc2ccccc2N(C(=O)CCl)c2cscc21>>CN(C)CC1CCCCN1CC(=O)N1c2ccccc2NC(=O)c2cscc21,,CC#N,,,,test
US06982260B1,BrC1CCCC1.COC1=CCC=C(OC)C1>>COC1=CCC=C(OC)C1C1CCCC1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20140142081A1,CNC(N)=S.COC(=O)CC(=O)CCl>>CNc1nc(CC(=O)OC)cs1,,CO,,,,test
US20130336965A1,CS[C@H]1[C@@H](C)C[C@@H](c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)C[C@H]1NC(=O)OC(C)(C)C>>CS[C@H]1[C@@H](C)C[C@@H](c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)C[C@H]1N,,C1COCCO1,,Cl,,test
US20120016014A1,NCCc1ccccc1.O=C(O)c1sc2ccccc2c1Br>>O=C(NCCc1ccccc1)c1sc2ccccc2c1Br,,CCOC(C)=O,CN(C)C=O,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20050239841A1,CN.COc1ccc([C@@]23CCC(=O)C[C@@H]2N(C)CC3)cc1OC.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>COc1ccc([C@@]23CC[C@H](N(C)C(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)C[C@@H]2N(C)CC3)cc1OC,,ClCCl,,[BH3-]C#N.[Na+],,test
US20160264579A1,O=C(O)c1cccn(-c2ccccc2)c1=O.O=C1CCC(=O)N1I>>O=C(O)c1cc(I)cn(-c2ccccc2)c1=O,,ClCCl,O=C(O)C(F)(F)F,O,,test
US04699992,CCOC(=O)C=CN(CC)CC.O=C(Cl)c1cc(F)c(Cl)cc1Cl>>CCOC(=O)C(=CN(CC)CC)C(=O)c1cc(F)c(Cl)cc1Cl,,C1COCCO1,,CCN(CC)CC,,test
US20100137299A1,CC(C)=NO.N#Cc1cc2c(cc1F)OCC21C(=O)N(C[C@H]2CCCO2)c2ccccc21>>Nc1noc2cc3c(cc12)C1(CO3)C(=O)N(C[C@H]2CCCO2)c2ccccc21,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20140315901A1,Cc1cncc(B(O)O)c1.N#Cc1c[nH]c2nc(Cl)cc(I)c12>>Cc1cncc(-c2cc(Cl)nc3[nH]cc(C#N)c23)c1,,C1COCCO1,O,[F-].[K+],,test
US20110287937A1,CCOC(=O)c1cc2cccnc2n(Cc2ccccc2OC)c1=O>>COc1ccccc1Cn1c(=O)c(C(=O)O)cc2cccnc21,,C1COCCO1,,Cl,,test
US20160075692A1,CCOC(=O)CI.O=C1NCCCN1c1cccc2c1cnn2-c1ccccc1F>>CCOC(=O)CN1CCCN(c2cccc3c2cnn3-c2ccccc2F)C1=O,,CN(C)C=O,,[H-].[Na+],,test
US20120088755A1,COc1ccc2[nH]c(C)nc2c1.O=S(=O)(Cl)Cl>>COc1ccc2[nH]c(C)nc2c1Cl,,CC(=O)O,,O,,test
US20070078136A1,BrBr.CCc1c(Cl)cnnc1N.CCc1cc(N)nnc1Cl>>CCc1c(Cl)nnc(N)c1Br,,CCOC(C)=O,CO,O=C([O-])O.[Na+],,test
US20130331460A1,Br.COc1cc(CO)c(OC)cc1Cl>>COc1cc(CBr)c(OC)cc1Cl,,ClCCl,,,,test
US04599357,CC(Br)C(=O)Cl.CCOC(=O)C1Cc2ccccc2N1>>CCOC(=O)C1Cc2ccccc2N1C(=O)C(C)Br,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20100081825A1,COC(=O)c1ccc2ccc(CO)cc2c1>>COC(=O)c1ccc2ccc(C=O)cc2c1,O=[Mn]=O,Cc1ccccc1,,,,test
US20100273795A1,CC(C)N=C=O.Cc1cc(C)cc(Oc2ccc(C#N)cc2S(=O)(=O)N2CCNCC2)c1>>Cc1cc(C)cc(Oc2ccc(C#N)cc2S(=O)(=O)N2CCN(C(=O)NC(C)C)CC2)c1,,ClCCl,,CCN(CC)CC,,test
US20120015962A1,CC(C)(C)[Si](C)(C)Cl.O=[N+]([O-])c1cc(Cl)ccc1-c1cccc(O)c1>>CC(C)(C)[Si](C)(C)Oc1cccc(-c2ccc(Cl)cc2[N+](=O)[O-])c1,,CN(C)C=O,,c1c[nH]cn1,,test
US20030134867A1,O=C(Cc1ccc(F)cc1)N1CC(N2CCOCC2)CN1C(=O)OCc1ccccc1>>O=C(Cc1ccc(F)cc1)N1CC(N2CCOCC2)CN1,[Pd],CO,,Cl,,test
US20110002855A1,COc1ccc2[nH]c3c(c2c1)CNCC3.O=C(CCl)N1CCN(C2CCC2)CC1>>COc1ccc2c3c([nH]c2c1)CCN(CC(=O)N1CCN(C2CCC2)CC1)C3,,CC#N,ClCCl,[I-].[K+],O=C([O-])O.[Na+],test
US20160024110A1,CCCOC(=O)CC(=O)CCl.CCOC(OCC)OCC>>CCCOC(=O)/C=C(\CCl)OCC,O=S(=O)(O)O,ClC(Cl)Cl,,O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3,,test
US04469698,C=CCn1c(=O)c2[nH]c(C)nc2n(CCCC)c1=O>>CCCCn1c(=O)n(CCC)c(=O)c2[nH]c(C)nc21,[Pd],CCO,,,,test
US20050148624A1,NCc1ccccc1.O=C(O)c1oc(=O)c2ccc(F)cc2c1-c1ccccc1>>O=C(O)c1c(-c2ccccc2)c2cc(F)ccc2c(=O)n1Cc1ccccc1,,CO,,CCN(CC)CC,,test
US20070088018A1,N#Cc1cnccc1C(F)(F)F>>NCc1cnccc1C(F)(F)F,[Ni],CCO,,N,,test
US20110178115A1,COC(=O)Cc1cn(C[C@@H](CCO[Si](C)(C)C(C)(C)C)NS(=O)(=O)c2ccc(F)cc2)c2ncccc12>>COC(=O)Cc1cn(C[C@@H](CCO)NS(=O)(=O)c2ccc(F)cc2)c2ncccc12,,ClCCl,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100120721A1,COCC1(OP(=O)(O)O)CCN(c2c(F)cc(N3C[C@H](CNC(C)=O)OC3=O)cc2F)CC1.NCCCC[C@H](N)C(=O)O>>COCC1(OP(=O)(O)O)CCN(c2c(F)cc(N3C[C@H](CNC(C)=O)OC3=O)cc2F)CC1.NCCCC[C@H](N)C(=O)O,,O,,,,test
US20060270874A1,NS(=O)(=O)/C=C/c1ccccc1Cl.O=C(Cl)c1ccc(Br)cc1Cl>>O=C(NS(=O)(=O)/C=C/c1ccccc1Cl)c1ccc(Br)cc1Cl,,C1COCCO1,,O,[H-].[Na+],test
US20120123120A1,CCOC(=O)[C@H](Cc1cc(OC(=O)OC(C)(C)C)c(OC(=O)OC(C)(C)C)cc1I)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H](Cc1cc(OC(=O)OC(C)(C)C)c(OC(=O)OC(C)(C)C)cc1I)C(=O)O,,C1CCOC1,O,CC(=O)O,[Li+].[OH-],test
US20020198195A1,CC(C)(C)OC(=O)NCC1CCN(C#N)CC1.NO>>CC(C)(C)OC(=O)NCC1CCN(C(=N)NO)CC1,,CC(C)O,,CCN(CC)CC,Cl,test
US20040138211A1,COC(=O)C(=Cc1ccc(OCCOc2ccc3ncccc3c2)cc1)C(=O)OC>>COC(=O)C(Cc1ccc(OCCOc2ccc3ncccc3c2)cc1)C(=O)OC,[Pd],C1COCCO1,CO,[H][H],,test
US20130252944A1,COc1ccc(Cn2cc3c(n2)C(C)OC(C)(C)c2sc(Nc4nccc(C)n4)nc2-3)cc1>>Cc1ccnc(Nc2nc3c(s2)C(C)(C)OC(C)c2n[nH]cc2-3)n1,,O=C(O)C(F)(F)F,,,,test
US20110028467A1,COc1c(Br)cc(C(=O)Cl)cc1Br.FC(F)(F)Oc1ccc(-c2cnc3c(c2)NCCO3)cc1>>COc1c(Br)cc(C(=O)N2CCOc3ncc(-c4ccc(OC(F)(F)F)cc4)cc32)cc1Br,,ClCCl,,CCN(CC)CC,,test
US20120040985A1,COc1ccc(C(C)(C)c2c[nH]c(=S)n2-c2ccc(F)cc2)cc1Cl.N#Cc1cc(CBr)ccc1Cl>>COc1ccc(C(C)(C)c2cnc(SCc3ccc(Cl)c(C#N)c3)n2-c2ccc(F)cc2)cc1Cl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04578378,C=CC(N)=O.CCOC(=O)CC(=O)OCC>>CCOC(=O)C1CCC(=O)NC1=O,,C1CCOC1,CCOC(C)=O,CC(=O)O,[H-].[Na+],test
US20160272596A1,COC(=O)c1ccc(C(=O)N2C[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)N(Cc3c(C)ccc4ccccc34)c3ccccc32)cc1>>Cc1ccc2ccccc2c1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)CN(C(=O)c2ccc(C(=O)O)cc2)c2ccccc21,,C1CCOC1,O,[Li+].[OH-],,test
US20120083488A1,CC1(C)O[C@H](COc2ccc3c(c2)C(=O)c2c([nH]c4cc(Br)ccc24)C3(C)C)[C@H](C(C)(C)O[SiH2]C(C)(C)C)O1>>CC1(C)c2ccc(OC[C@@H](O)[C@H](O)CO)cc2C(=O)c2c1[nH]c1cc(Br)ccc21,,C1CCOC1,CO,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US20060211724A1,CC(C)OC(=O)c1ncccc1C1(C)OCCO1.O=C1CCC(=O)N1Cc1ccc2c(c1)OCO2>>CC1(c2cccnc2C(O)=C2CC(=O)N(Cc3ccc4c(c3)OCO4)C2=O)OCCO1,CO,C1CCOC1,,[H-].[Na+],,test
US20140213599A1,CC(CO)N(C)c1cc(Cl)nc(=O)[nH]1.CS(=O)(=O)Cl>>CC(COS(C)(=O)=O)N(C)c1cc(Cl)nc(=O)[nH]1,,C1CCOC1,,CCN(CC)CC,,test
US05952266,Brc1ccc2c(c1)C1(CCS2)OCCO1.O=C=O>>O=C(O)c1ccc2c(c1)C1(CCS2)OCCO1,,CCCCCC,,C1CCOC1,[Li]CCCC,test
US20080125469A1,CCc1ccc(N)cc1.NO.OC(O)C(Cl)(Cl)Cl>>CCc1ccc(NC(=O)/C=N/O)cc1,,Cl,O,O=S(=O)([O-])[O-].[Na+].[Na+],,test
US05981533,COc1cccc(Nc2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)c1>>Oc1cccc(Nc2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)c1,,c1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2cccc(F)c23)cc1.CS(=O)(=O)c1cccc(N)c1>>CS(=O)(=O)c1cccc(Nc2nc3cccc(F)c3c3cn[nH]c23)c1,C1COCCO1,CO,,Cl,,test
US20100048537A1,CCOC(=O)N1CCC(=O)c2ccoc2C1>>CN1CCC(O)c2ccoc2C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04416821,C1CCOC1.COC1=CC2=CC[C@@H]3C(=CC[C@]4(C)C(=O)CC[C@@H]34)[C@@]2(C)CC1>>C=C1C[C@H]2[C@@H]3CC=C4C=C(OC)CC[C@]4(C)C3=CC[C@]2(C)C1=O,,C1CCOC1,,C[O-].[Na+],,test
US04177291,BrBr.CC(N)C(=O)CC(C)(C)Cc1ccc(Cl)cc1>>CC(Br)C(=O)CC(C)(C)Cc1ccc(Cl)cc1,,ClC(Cl)(Cl)Cl,,,,test
US20050032786A1,CC(C)(C)OC(=O)CCc1ccnc(-c2nc(=O)c3ccc(Br)cc3s2)c1>>O=C(O)CCc1ccnc(-c2nc(=O)c3ccc(Br)cc3s2)c1,,O=C(O)C(F)(F)F,,,,test
US20090042852A1,CCc1cnc(-c2cnc(N3CCC(C(=O)OC)CC3)c(Cl)c2OC)o1>>CCc1cnc(-c2cnc(N3CCC(C(=O)O)CC3)c(Cl)c2OC)o1,,C1CCOC1,,[Li+].[OH-],,test
US20080161341A1,CC(=O)Cl.Fc1ccc(-c2nc3occn3c2-c2ccc3nnc(C4CCNC4)n3c2)cc1>>CC(=O)N1CCC(c2nnc3ccc(-c4c(-c5ccc(F)cc5)nc5occn45)cn23)C1,,ClCCl,,,,test
US20090186831A1,Cc1ccc(S(=O)(=O)O[C@@H]2CN(C(=O)OCc3ccccc3)[C@@H]3[C@@H](O)CO[C@H]23)cc1>>Cc1ccc(S(=O)(=O)O[C@@H]2CN[C@@H]3[C@@H](O)CO[C@H]23)cc1,[Pd],CCO,,[H][H],,test
US20130267510A1,CC[C@@](C)(N)C(=O)Nc1ccc(Oc2cccc3c2C2(CC2)COC3)nc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC[C@@]1(C)NC(=O)N(c2ccc(Oc3cccc4c3C3(CC3)COC4)nc2)C1=O,,ClCCl,,,,test
US20030095958A1,CCOC(=O)c1cc(Br)cc([N+](=O)[O-])c1N1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCN(c2c(CO)cc(Br)cc2[N+](=O)[O-])CC1,,C1CCOC1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20100184815A1,CCCn1nc(Cc2ccc(C)cc2)cc1COC(=O)c1ccc(SC(C)(C)C(=O)OC(C)(C)C)cc1>>CCCn1nc(Cc2ccc(C)cc2)cc1COC(=O)c1ccc(SC(C)(C)C(=O)O)cc1,,CO,,C1COCCO1,,test
US20130040931A1,Brc1ccccc1I.CC(C)(C)CO>>CC(C)(C)COc1ccccc1Br,[Cu]I,,,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US20080039452A1,C=O.CC(C)(C)OC(=O)N1C=CCC1.Nc1ccccc1>>CC(C)(C)OC(=O)N1CC[C@@H]2CNC3C=CC=CC3[C@@H]21,,CO,,[Na],,test
US20090326059A1,CC(C)(C)CC(=O)Cl.Cc1cc(OCc2ccc(F)cc2)cc(C)c1N>>Cc1cc(OCc2ccc(F)cc2)cc(C)c1NC(=O)CC(C)(C)C,,ClCCl,,CCN(CC)CC,O,test
US20100216788A1,CN(C(=O)c1cccc(Oc2ccc(N)cc2Cl)c1)C(C)(C)C.O=C(OCCn1ccc2ncnc(Cl)c21)c1ccccc1>>CN(C(=O)c1cccc(Oc2ccc(Nc3ncnc4ccn(CCO)c34)cc2Cl)c1)C(C)(C)C,,CC(C)O,,O=C([O-])O.[Na+],,test
US20140213554A1,CC(C)(C)OC(=O)Nc1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1.ClC(Cl)(Br)C(Cl)(Cl)Br>>CC(C)(C)OC(=O)Nc1cnc2c(c1)cc(Br)n2S(=O)(=O)c1ccccc1,,C1CCOC1,,[Li]C(C)(C)C,,test
US20070208062A1,C=CCOC[C@@H]1CC(c2ccc(Br)cn2)=NO1.CC1(C)OB(c2ccc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)OC1(C)C>>C=CCOC[C@@H]1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100273853A1,CCOC(=O)C(C(=O)OCC)c1ccc(N)c(F)c1>>CCOC(=O)Cc1ccc(N)c(F)c1,,CCO,O,[Na+].[OH-],,test
US05039686,CSC(=C[N+](=O)[O-])SC.NCCNc1ccc(Cl)nc1>>O=[N+]([O-])C=C1NCCN1c1ccc(Cl)nc1,,CO,ClCCl,CCO,,test
US05756735,CCCn1c(N)c(N)c(=O)[nH]c1=O.COc1cc(C=CC(=O)O)cc(OC)c1OC>>CCCn1c(=O)[nH]c(=O)c2[nH]c(/C=C/c3cc(OC)c(OC)c(OC)c3)nc21,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US04804400,CC1=C(C)C(=O)N(c2cc(C(=O)O)c(Cl)cc2F)C1=O.ClC=CCCl>>CC1=C(C)C(=O)N(c2cc(C(=O)OCC=CCl)c(Cl)cc2F)C1=O,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070255062A1,COC[C@H](C)Oc1cc(OCc2ccccc2)cc(C(=O)OC)c1>>COC[C@H](C)Oc1ccc(OCc2ccccc2)cc1C(=O)O,,CO,O,C1CCOC1,[Na+].[OH-],test
US20100216844A1,CCOC(=O)C(O)C(Cc1ccccc1)NC(=O)c1cccnc1-c1csc(-c2ccccc2)n1>>O=C(NC(Cc1ccccc1)C(O)C(=O)O)c1cccnc1-c1csc(-c2ccccc2)n1,,O,,C1CCOC1,,test
US20150045359A1,CCOc1ccc(-c2nc3ccc([C@@H]4CN(C(=O)OC(C)(C)C)CCO4)cc3o2)cn1.Cl>>CCOc1ccc(-c2nc3ccc([C@@H]4CNCCO4)cc3o2)cn1.Cl,,C1COCCO1,,,,test
US20140221339A1,COC(=O)c1cc(OCCCC(F)(F)F)ccc1Cl>>O=C(O)c1cc(OCCCC(F)(F)F)ccc1Cl,,CO,,Cl,[Li+].[OH-],test
US20030232848A1,BrCC1CC1.Cn1nc(O)c(-c2ccc3c(c2)OCO3)c1N>>Cn1nc(OCC2CC2)c(-c2ccc3c(c2)OCO3)c1N,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150045349A1,Cc1ccccc1-n1ccc(Cl)c(C#N)c1=O.O=C1CCC(=O)N1Br>>Cc1ccccc1-n1cc(Br)c(Cl)c(C#N)c1=O,,CN(C)C=O,O,,,test
US20120115856A1,COC(=N)C(Cl)(Cl)Cl.Nc1cc(-c2nc3ccccc3o2)ccc1NC1CCOCC1>>ClC(Cl)(Cl)c1nc2cc(-c3nc4ccccc4o3)ccc2n1C1CCOCC1,,CC(=O)O,,Cl,O,test
US20070259864A1,CS(=O)(=O)NCCN1CC2CN(Cc3ccc(C#N)cc3)CC(C1)O2.N#Cc1ccc(CBr)cc1>>CS(=O)(=O)N(CCN1CC2CN(Cc3ccc(C#N)cc3)CC(C1)O2)Cc1ccc(C#N)cc1,,O,,[H-].[Na+],,test
US20140225069A1,CC(C)c1ccccc1Nc1ccc(-c2ccccc2)cc1N.O=Cc1ccccc1>>CC(C)c1ccccc1-n1c(-c2ccccc2)nc2cc(-c3ccccc3)ccc21,,CN(C)C=O,,O=S([O-])[O-].[Na+].[Na+],,test
US20080221096A1,CC1(C)CCc2c(c3c([nH]c2=O)oc2c(NCCCN4CCCC4=O)ncnc23)C1.CNCc1ccccc1>>CN(Cc1ccccc1)c1nc2oc3c(NCCCN4CCCC4=O)ncnc3c2c2c1CCC(C)(C)C2,,C1CCOC1,,[H-].[Na+],,test
US20030236297A1,CC(N)(CO)CCc1cc(C#CCCCc2ccccc2)cs1.Cl.[OH-]>>CC(N)(CO)CCc1cc(C(=O)CCCCc2ccccc2)cs1.Cl,,CO,,O=S(=O)(O)O,,test
US20030153596A1,CC(C)(C)OC(=O)NCc1ccc(N)cc1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NCc1ccc(NS(C)(=O)=O)cc1,,ClCCl,O,CCN(CC)CC,Cl,test
US20100280013A1,C/C=C\c1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1N1C[C@@H](C)N(C(=O)CBr)C[C@@H]1C.CC(C)Oc1ccc(C2(C)NC(=O)NC2=O)cc1>>C/C=C\c1cc(C(O)(C(F)(F)F)C(F)(F)F)ccc1N1C[C@@H](C)N(C(=O)CN2C(=O)N[C@@](C)(c3ccc(OC(C)C)cc3)C2=O)CC1C,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04710508,C#CC(C[Si](C)(C)C)c1ncccc1CO>>CCC#CC1(CO)C=CC=NC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05151436,COC[C@@H]1CCCN1N.O=C1CCCCC1c1cnc2ccccc2c1>>COC[C@@H]1CCCN1N=C1CCCCC1c1cnc2ccccc2c1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080269305A1,CC(C)(C)OC(=O)c1ccccc1-c1ccc(CBr)cc1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3C2=O)cc1,,CN(C)C=O,,[K],,test
US20080293716A1,COc1ccc(CN)cc1.Nc1nccc(-c2ccc(C(=O)O)s2)n1>>COc1ccc(CNC(=O)c2ccc(-c3ccnc(N)n3)s2)cc1,,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20150148341A1,Brc1ccccn1.COC(=O)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C[C@@H]1CCN(S(=O)(=O)c1ccc(C(F)(F)F)cc1)C2>>O=C(c1ccccn1)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C[C@@H]1CCN(S(=O)(=O)c1ccc(C(F)(F)F)cc1)C2,,C1CCOC1,,[Li]CCCC,,test
US20040229861A1,CC(C)(C)OC(=O)N1CCC(Nc2cc(F)cnc2N)CC1.O=C(n1ccnc1)n1ccnc1>>CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3ncc(F)cc32)CC1,,CC#N,,,,test
US20020037891A1,Fc1ccc(N2CCNCC2)cc1.O=C(O)c1cn(-c2ccc(F)cc2F)c2nc3cc(F)c(F)cc3cc2c1=O>>O=C(O)c1cn(-c2ccc(F)cc2F)c2nc3cc(N4CCN(c5ccc(F)cc5)CC4)c(F)cc3cc2c1=O,,CS(C)=O,,,,test
US20100004238A1,CC(C)(C)OC(=O)NCCn1ccc2ncnc(Cl)c21.Nc1ccc(Oc2ccc3ccsc3c2)c(Cl)c1>>CC(C)(C)OC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4ccc5ccsc5c4)c(Cl)c3)c21.Cl,,CCOC(C)=O,,CC(C)O,,test
US20020045615A1,CC(N)=S.COC(=O)Nc1nc2c(OC)ccc(C(=O)CBr)c2s1>>COC(=O)Nc1nc2c(OC)ccc(-c3csc(C)n3)c2s1,,C1COCCO1,CCOC(C)=O,,,test
US20160075663A1,CC(C)(C)CC(=O)Nc1nc2ccc(CO)cc2n1C1CCC1>>CC(C)(C)CC(=O)Nc1nc2ccc(C=O)cc2n1C1CCC1,,CCOC(C)=O,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US05336778,CCCCc1nnc(S(=O)(=O)Cc2ccc(Cl)cc2)n1Cc1ccc(-c2ccccc2C#N)cc1.C[Sn](C)(C)N=[N+]=[N-]>>CCCCc1nnc(S(=O)(=O)Cc2ccc(Cl)cc2)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,CO,,,,test
US20090048203A1,COc1ccc(CBr)cc1.OC1CCCC(O)C1>>COc1ccc(COC2CCCC(O)C2)cc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US04886814,BrBr.CC(=O)c1nc(C(F)(F)F)oc1C>>Cc1oc(C(F)(F)F)nc1C(=O)CBr,,CC(=O)O,,Br,,test
US06156783,CI.Cc1cc(N2CCCC2=O)ccc1-c1ccc(C(=O)O)cc1>>COC(=O)c1ccc(-c2ccc(N3CCCC3=O)cc2C)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140073623A1,COC(=O)c1c(N)ccc2c1nc1n2CCC1.O=S(=O)(Cl)c1ccc(F)cc1Br>>COC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2Br)ccc2c1nc1n2CCC1,,ClCCl,c1ccncc1,,,test
US20140296260A1,CC[C@H](N)c1nc2cccc(F)c2c(=O)n1-c1cccc(CC(F)(F)F)c1.Clc1ccnc2[nH]cnc12>>CC[C@H](Nc1ccnc2[nH]cnc12)c1nc2cccc(F)c2c(=O)n1-c1cccc(CC(F)(F)F)c1,,CC(C)(C)O,,CCN(C(C)C)C(C)C,,test
US05703052,CC(=O)O[C@@H]1C[C@@]2(C)[C@@H](C[C@@H]3O[C@]4(CC[C@@H](C)CO4)[C@@H](C)[C@@H]32)[C@@H]2CC[C@H]3C[C@@H](OC(C)=O)C(=O)C[C@]3(C)[C@@H]12>>C[C@@H]1CC[C@@]2(OC1)O[C@H]1C[C@H]3[C@@H]4CC[C@H]5C[C@@H](O)CC[C@]5(C)[C@H]4[C@H](O)C(=O)[C@]3(C)[C@H]1[C@@H]2C,,C1CCOC1,CO,C[O-].[Na+],,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4ccc(OC)cc4)nc(Cl)c3n2)cc1.Nc1ccc2c(c1)NC(=O)CCC2>>COc1ccc(-c2nc(Nc3ccc4c(c3)NC(=O)CCC4)c3[nH]ncc3n2)cc1,C1COCCO1,CO,,Cl,,test
US20090137609A1,CCC(CC)(c1ccc(C#CC2(O)CCCC2)c(C)c1)c1ccc(-c2ccc(CC(=O)OC)cc2)c(C)c1>>CCC(CC)(c1ccc(C#CC2(O)CCCC2)c(C)c1)c1ccc(-c2ccc(CC(=O)O)cc2)c(C)c1,,C1CCOC1,CO,[Na+].[OH-],[Cl-].[NH4+],test
US20150353498A1,CC(C)(C)OC(=O)CCCCc1cc2cc(-c3cc(Cc4ccc(F)cc4)on3)ccc2c(=O)n1-c1ccc(F)cc1>>O=C(O)CCCCc1cc2cc(-c3cc(Cc4ccc(F)cc4)on3)ccc2c(=O)n1-c1ccc(F)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100143341A1,CO.COC(=O)c1ccc([N+](=O)[O-])c(F)c1>>COc1cc(C(=O)O)ccc1[N+](=O)[O-],,C1CCOC1,O,[H-].[Na+],,test
US20150291632A1,C[S+](C)(C)=O.O=C(CCc1ccc(F)cc1F)c1ccc(Oc2ccc(Cl)cn2)cn1>>Fc1ccc(CCC2(c3ccc(Oc4ccc(Cl)cn4)cn3)CO2)c(F)c1,,C1CCOC1,,[H-].[Na+],,test
US20090247559A1,CC(C)(C)OC(=O)N1CCOC(CCl)C1.COC(=O)c1ccc(O)cc1>>COC(=O)c1ccc(OCC2CN(C(=O)OC(C)(C)C)CCO2)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130116235A1,CN1CCn2nc(Nc3cc(-c4ccnc(N5CCn6c(cc7c6[C@H]6CC[C@@H]7C6)C5=O)c4C=O)cn(C)c3=O)cc2C1>>CN1CCn2nc(Nc3cc(-c4ccnc(N5CCn6c(cc7c6C6CCC7C6)C5=O)c4CO)cn(C)c3=O)cc2C1,,CO,,[BH4-].[Na+],,test
US20150291655A1,C=C(C)[C@@H]1CC[C@]2(NC(CN)C(F)(F)F)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(C(=O)OCc7ccccc7)CC6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.C=CS(=O)(=O)C=C>>C=C(C)[C@@H]1CC[C@]2(NC(CN3CCS(=O)(=O)CC3)C(F)(F)F)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(C(=O)OCc7ccccc7)CC6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,CC(C)O,,,,test
US20100197744A1,BrCc1ccccc1.CC(=O)Nc1cc2ccccc2cc1O>>CC(=O)Nc1cc2ccccc2cc1OCc1ccccc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150057265A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1c(N)oc2cc(Br)cnc12>>CCOC(=O)c1c(NC(=O)OC(C)(C)C)oc2cc(Br)cnc12,CN(C)c1ccncc1,CC#N,,,,test
US04167628,CC(=O)OC(C)=O.COc1ccc(-c2nc3ccc(C=O)cc3o2)cc1.Cc1cc(N)c(O)cc1C>>COc1ccccc1-c1nc2ccc(C=Cc3nc4cc(C)c(C)cc4o3)cc2o1,,Cc1ccccc1C,O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20140323475A1,CCO.N#Cc1cncc2c1ccn2Cc1cc(Cl)ccc1OCc1ccc(F)cc1F.O.[Na+]>>O=C([O-])c1cncc2c1ccn2Cc1cc(Cl)ccc1OCc1ccc(F)cc1F.[Na+],,O,,Cl,,test
US07214673B2,NC1C(=O)Nc2ccccc2NC1=O.O=C(Cl)C1CCCC1>>O=C(NC1C(=O)Nc2ccccc2NC1=O)C1CCCC1,,CN(C)C=O,,CCN(CC)CC,,test
US05112998,COCO[C@H]1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@]2(O)C=C[C@H]3[C@@H]4CC[C@H](C(C)C5OCC(C)(C)CO5)[C@@]4(C)CC[C@@H]3[C@@]12C>>COCO[C@H]1C[C@H](O[Si](C)(C)C(C)(C)C)CC2=CC=C3[C@@H]4CC[C@H](C(C)C5OCC(C)(C)CO5)[C@@]4(C)CC[C@@H]3[C@]21C,,CCOC(C)=O,,CC(=O)O,,test
US20130217671A1,CCCC(=O)c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1N[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1>>CCCC(=O)c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1N[C@@H]1CC[C@@H](N)CC1,,C1CCOC1,,Cl,O,test
US20110313003A1,CC(=O)OC(C)=O.CC1(CO)Cc2cc(F)ccc2O1>>CC(=O)OCC1Cc2cc(F)ccc2O1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20130237501A1,CCOC(=O)c1c(-c2ccc(F)cc2)oc2cc(Nc3cccc(Br)c3)c(C3CC3)cc12.CS(=O)(=O)Cl>>CCOC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(c3cccc(Br)c3)S(C)(=O)=O)c(C3CC3)cc12,,C1CCOC1,CCOC(C)=O,O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20030191308A1,CC(=O)OC(C)=O.COc1cc2c(=O)[nH]cnc2cc1OCC(O)CN1CCN(C)CC1>>COc1cc2c(=O)[nH]cnc2cc1OCC(CN1CCN(C)CC1)OC(C)=O,,CCOCC,,O,,test
US20080004271A1,COCCCN.CS(=O)c1nc(-c2ccc(Cl)c(Cl)c2)c2c(N)c(C(N)=O)sc2n1>>COCCCNc1nc(-c2ccc(Cl)c(Cl)c2)c2c(N)c(C(N)=O)sc2n1,,CS(C)=O,,,,test
US20160000785A1,CC(C)(C)OC(=O)N1CCC(n2cc(-c3ccc(F)c(C(F)(F)F)c3)nc2C2CCN(c3ncnc(N)c3C(N)=O)CC2)C1>>NC(=O)c1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2C2CCNC2)CC1,,C1COCCO1,CO,Cl,,test
US20020132812A1,N#CC=C(c1ccccn1)c1cc([N+](=O)[O-])cc2c1OCC2>>N#CCC(c1ccccn1)c1cc(N)cc2c1OCC2,[Pd],CCO,,,,test
US03931188,CCOC(=O)CCl.COc1ccc(C=O)cc1>>CCOC(=O)C1OC1c1ccc(OC)cc1,,Cc1ccccc1,,CCO,,test
US20110112134A1,CC(C)(C)OC(=O)C1C(=O)CCc2cc3ncccc3n21>>O=C1CCc2cc3ncccc3n2C1,,Cc1ccccc1,,,,test
US05217976,CCc1cc2c(ccc(=O)n2Cc2ccc(-c3ccccc3S(=O)(=O)NC(C)(C)C)cc2)c(CC)n1>>CCc1cc2c(ccc(=O)n2Cc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c(CC)n1,,O=C(O)C(F)(F)F,,,,test
US20160009714A1,C[C@@H]1C[C@H](NC(=O)OC(C)(C)C)CN(c2ccncc2N)C1.O=C(O)c1ccc2ccc(N3CCC4(CCOCC4)CC3)cc2n1>>C[C@@H]1C[C@H](N)CN(c2ccncc2NC(=O)c2ccc3ccc(N4CCC5(CCOCC5)CC4)cc3n2)C1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04983627,CCOCC.ON=C1CC2C=CCCC12Cl.[Li]C>>CC=CCCCC(C)=NO,,CCOCC,CCOCC,[Cl-].[NH4+],,test
US05071844,COc1ccc(CCBr)cc1.O=S1Cc2ccccc2N(C[C@@H]2CCCN2)c2ccccc21>>COc1ccc(CCN2CCC[C@H]2CN2c3ccccc3CS(=O)c3ccccc32)cc1,,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20110003789A1,CC(C)(C)OC(=O)NC1CNC1.O=C(NC[C@H]1CO1)OCc1ccccc1>>CC(C)(C)OC(=O)NC1CN(CC(O)CNC(=O)OCc2ccccc2)C1,,CO,,O=S(=O)([O-])[O-].[Mg+2],,test
US20080145944A1,Cc1cccc(C)c1B(O)O.O=C1CCC(=O)N1Br>>Cc1cccc(CBr)c1B(O)O,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US05055572,Cc1cc(SCC2=C(C(=O)O)N3C(=O)[C@@H](NC(=O)C(=O)c4csc(N)n4)[C@H]3SC2)n2nc(C(N)=O)nc2n1.NOCc1nc(=O)c(O)c[nH]1>>Cc1cc(SCC2=C(C(=O)O)N3C(=O)[C@@H](NC(=O)/C(=N\OCc4nc(=O)c(O)c[nH]4)c4csc(N)n4)[C@H]3SC2)n2nc(C(N)=O)nc2n1,,CC(=O)N(C)C,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20090233920A1,CC(C)(C)C(=O)Cl.COCCCn1cc(CN(C(=O)[C@@H]2C[C@H](N)CN(C(=O)OCC3c4ccccc4-c4ccccc43)C2)C2CC2)c2ccccc21>>COCCCn1cc(CN(C(=O)[C@H]2CNC[C@@H](NC(=O)C(C)(C)C)C2)C2CC2)c2ccccc21,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100256156A1,Br[Mg]C1CCC1.C1CCOC1.CC1C=CC(C=O)(c2ccccc2)O1>>Cc1oc(-c2ccccc2)cc1C(O)CC(C)C,,C1CCOC1,,Cl,O,test
US20140221311A1,N#CCCl.Sc1ccccc1Br>>N#CCSc1ccccc1Br,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04920130,O=C(O)c1ccc(C=Cc2ccc(S(=O)Cc3ccc4ccccc4n3)cc2)cc1.OO>>O=C(O)c1ccc(C=Cc2ccc(S(=O)(=O)Cc3ccc4ccccc4n3)cc2)cc1,,ClCCl,,CC(=O)O,,test
US20130281474A1,N#CC1CCC2(SCCS2)C1=O.Nc1[nH]ncc1-c1ccc(-c2ccccc2)nc1>>Nc1c2c(nc3c(-c4ccc(-c5ccccc5)nc4)cnn13)C1(CC2)SCCS1,,Cc1ccccc1,,,,test
US20100256156A1,COC(=O)c1cc(Br)oc1C.OB(O)c1cccc(F)c1>>COC(=O)c1cc(-c2cccc(F)c2)oc1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US05728835,Nc1ccc(C(=O)N(CCN2CCC(C(=O)c3ccccc3)CC2)c2cccnc2)cc1.O=C(O)/C=C\C(=O)O>>Nc1ccc(C(=O)N(CCN2CCC(C(=O)c3ccccc3)CC2)c2cccnc2)cc1.O=C(O)/C=C\C(=O)O,,CCO,,,,test
US20100190747A1,N#CCCN.O=S(=O)(Cl)CCCCl>>N#CCCNS(=O)(=O)CCCCl,,C1CCOC1,,CCN(CC)CC,CCOCC,test
US20020091148A1,CCOC(=O)c1[nH]c2ccccc2c1-c1ccncc1.NN>>NNC(=O)c1[nH]c2ccccc2c1-c1ccncc1,,CCO,,O,,test
US20040192708A1,Cc1nn(C)c(Cl)c1S(=O)(=O)Nc1ccc(Cc2nc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1>>Cc1nn(C)cc1S(=O)(=O)Nc1ccc(Cc2nc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1,,CO,,,,test
US20120053171A1,COc1ccc(C2(O)CC2)cc1Br.C[Si](C)(C)Cl>>COc1ccc(C2(O[Si](C)(C)C)CC2)cc1Br,,C1CCOC1,O,CCN(CC)CC,,test
US20130261106A1,CC(C)Oc1cc(N2CCC[C@@H](NC3COC3)C2)ccc1[N+](=O)[O-].CI>>CC(C)Oc1cc(N2CCC[C@@H](N(C)C3COC3)C2)ccc1[N+](=O)[O-],,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20160222028A1,COC(=O)c1ccc(Br)c(CBr)c1.NCCO>>COC(=O)c1ccc(Br)c(CNCCO)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05705516,FC(CCBr)C(F)(F)Br.Sc1nccs1>>FC(CCSc1nccs1)C(F)(F)Br,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US07396844B1,CCNC.N#Cc1cccc(OCCNC(=O)c2ccc(C(=O)O)cc2)c1>>CCN(C)C(=O)c1ccc(C(=O)NCCOc2cccc(C#N)c2)cc1,,Cl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20110237628A1,CCOC(=O)C(c1c2c(nn1-c1ccc(Cl)cc1)CCCCC2)C1CCCCC1>>O=C(O)C(c1c2c(nn1-c1ccc(Cl)cc1)CCCCC2)C1CCCCC1,,CO,,[Na+].[OH-],,test
US20160221945A1,CCN(CC)S(F)(F)F.C[C@H]1[C@@H](O)C[C@@H](C(=O)NCc2ccnc(-c3cnc(C(F)(F)F)nc3)c2)N1C(=O)OC(C)(C)C>>C[C@H]1[C@H](F)C[C@@H](C(=O)NCc2ccnc(-c3cnc(C(F)(F)F)nc3)c2)N1C(=O)OC(C)(C)C,,ClCCl,,,,test
US20100204119A1,COC(=O)C[C@@H]1CC[C@@H](c2ccc(NCCO[Si](C)(C)C(C)(C)C)cc2)CC1.O=C(Cl)c1c(Cl)ncnc1Cl>>COC(=O)C[C@@H]1CC[C@@H](c2ccc(N(CCO[Si](C)(C)C(C)(C)C)C(=O)c3c(Cl)ncnc3Cl)cc2)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20080242665A1,CNC1CCN(C)CC1.O=Cc1cc2c(N3CCOCC3)nc(Cl)nc2s1>>CN1CCC(N(C)Cc2cc3c(N4CCOCC4)nc(Cl)nc3s2)CC1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US06514964B1,Fc1ccc(Br)c(CBr)c1.NCCCO>>OCCCNCc1cc(F)ccc1Br,,CC#N,,CCN(C(C)C)C(C)C,,test
US20030203926A1,CC(C)(C)OC(=O)NC1CCN(C(=O)c2ccc(Nc3nccc(-c4ccc(Cl)cc4)n3)cc2)CC1.Cl>>Cl.NC1CCN(C(=O)c2ccc(Nc3nccc(-c4ccc(Cl)cc4)n3)cc2)CC1,,CCO,,,,test
US05231181,COc1ccc2c(c1)CCN1C(=O)[C@H]3CCCN[C@H]3C[C@@H]21.CS(=O)(=O)Cl>>COc1ccc2c(c1)CCN1C(=O)[C@H]3CCCN(S(C)(=O)=O)[C@H]3C[C@@H]21,,CCCCCC,ClCCl,CCN(CC)CC,,test
US20120214767A1,NO.O=Cc1onc(-c2ccccc2)c1C(F)(F)F>>ON=Cc1onc(-c2ccccc2)c1C(F)(F)F,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20150094297A1,COc1cc(O)c2cc(-c3cn4nc(OC)sc4n3)oc2c1.COc1ccc(CN(C(=O)OC(C)(C)C)c2nc(CO)c(C)s2)c(OC)c1>>COc1ccc(CN(C(=O)OC(C)(C)C)c2nc(COc3cc(OC)cc4oc(-c5cn6nc(OC)sc6n5)cc34)c(C)s2)c(OC)c1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US04797417,CCI.COC(=O)CCC1OC(=O)C(O)=C1c1ccccc1>>CCOC1=C(c2ccccc2)C(CCC(=O)OC)OC1=O,,CN(C)C=O,O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20060194803A1,CC#N.Cc1ccc(N)cc1.Fc1ccc(N2CN=C(Cl)N=C2Cl)cc1>>Cc1ccc(Nc2nc(Cl)nc(Nc3ccc(F)cc3)n2)cc1,,CC#N,,CCN(C(C)C)C(C)C,O,test
US20100324041A1,CC(C)(C)OC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(c2c(Br)cnc3[nH]ccc23)CC1.OB(O)c1ccccc1>>CC(C)(C)OC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(c2c(-c3ccccc3)cnc3[nH]ccc23)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US04288435,CC(C)(C)OC(=O)c1ccccc1N.O=C(Br)CBr>>CC(C)(C)OC(=O)c1ccccc1NC(=O)CBr,,ClCCl,,CCN(CC)CC,,test
US20130090328A1,CC(=O)N1CCSc2ccccc2C1.O=C(OO)c1cccc(Cl)c1>>CC(=O)N1CCS(=O)c2ccccc2C1,,ClCCl,,,,test
US20130012499A1,CCC(=O)c1cccc(C(F)(F)F)c1.COc1cc2c(cc1Br)C(=O)C(=O)N2>>COc1cc2nc(-c3cccc(C(F)(F)F)c3)c(C)c(C(=O)O)c2cc1Br,,CCO,O,[K+].[OH-],,test
US06124323,O=[N+]([O-])c1cc(OCCBr)ccc1OCc1ccccc1.c1ccc(CC2CCNCC2)cc1>>O=[N+]([O-])c1cc(OCCN2CCC(Cc3ccccc3)CC2)ccc1OCc1ccccc1,,Cc1ccccc1,,,,test
US20020086898A1,CCCc1cc(=O)oc2c3c(c4c(c12)OC(C)(C)C=C4)OC(C)C(C)C3O.CCCc1cc(=O)oc2c3c(c4c(c12)OC(C)(C)CC4)O[C@@H](C)[C@H](C)[C@@H]3O>>C[C@@H]1Oc2c3c(c4c(-c5ccccc5)cc(=O)oc4c2[C@@H](O)[C@H]1C)OC(C)(C)C=C3,O=[Pt]=O,CO,,,,test
US04065467,C1CCNCC1.CCO.COC(=O)c1ccc(C(C)=O)c(O)c1.O=Cc1ccccc1O>>CC(C)Oc1ccccc1-c1cc(=O)c2ccc(C(=O)O)cc2o1,,CCO,O,,,test
US04676989,C=C1CCCC1.COC(=O)[C@H](CO)NC(=O)OCc1ccccc1>>COC(=O)[C@H](COC1(C)CCCC1)NC(=O)OCc1ccccc1,O=S(=O)(O)O,ClCCl,,O=C([O-])O.[Na+],,test
US20100256097A1,CC(C)(O)c1cc(F)c(-c2cc(C(N)=O)c(Nc3ccc(=O)[nH]n3)s2)c(F)c1.CI>>Cn1nc(Nc2sc(-c3c(F)cc(C(C)(C)O)cc3F)cc2C(N)=O)ccc1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100168080A1,COC(=O)c1cc(Cl)c(OC)cc1OCCCBr.OC1(c2ccc(Cl)cc2)CCNC1>>COC(=O)c1cc(Cl)c(OC)cc1OCCCN1CCC(O)(c2ccc(Cl)cc2)C1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20150376181A1,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21.CC1(c2cccc(F)c2)NC(=O)c2c(Cl)cc(Nc3cc(NC(=O)C4CC4)ncn3)c(=O)n21.Ic1cccnc1>>O=C1c2c(Cl)cc(Nc3ccncn3)c(=O)n2C2(CCCCC2)N1c1cccnc1,[Cu]I,CN(C)C=O,,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US20040167128A1,CCN(CC)CC/C=C/c1ccccc1S(=O)(=O)Nc1ccc2c(c1C(=O)OC)CCCC2>>CCN(CC)CC/C=C/c1ccccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2,,c1ccncc1,,[I-].[Li+],,test
US20060111375A1,CC(=O)Cl.COc1cc2nccc(Oc3ccc4[nH]ccc4c3)c2cc1OC>>COc1cc2nccc(Oc3ccc4c(ccn4C(C)=O)c3)c2cc1OC,,CN(C)C=O,,O,[H-].[Na+],test
US20090306041A1,C1CCOC1.COc1ccc(CN2CCc3cc(C4(C#N)CC4)ccc3C2=O)cc1>>COc1ccc(CN2CCc3cc(C4(C=O)CC4)ccc3C2=O)cc1,,Cc1ccccc1,ClCCl,CC(C)C[AlH]CC(C)C,,test
US20110105509A1,CC#Cc1cc(Cl)cc(F)c1N>>Cc1cc2cc(Cl)cc(F)c2[nH]1,[Cu]I,CN(C)C=O,,CCOC(C)=O,,test
US20070099927A1,CC(=O)OCCn1c(Cl)cnc(NCCc2ccccn2)c1=O>>O=c1c(NCCc2ccccn2)ncc(Cl)n1CCO,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20040229900A1,CC(C)(C)OC(=O)N1CC2CNCC(C2)C1.COc1ccc(OC(CCCOS(C)(=O)=O)c2ccc(C#N)cc2)cc1OC>>COc1ccc(OC(CCCN2CC3CC(C2)CN(C(=O)OC(C)(C)C)C3)c2ccc(C#N)cc2)cc1OC,,ClC(Cl)Cl,,CC#N,O=C([O-])[O-].[K+].[K+],test
US05053543,Brc1ccc(OCc2ccccc2)cc1.CON(C)C(=O)c1ccccc1N>>Nc1ccccc1C(=O)c1ccc(OCc2ccccc2)cc1,,C1CCOC1,,Cl,[Li]CCCC,test
US20150259330A1,CCOC(OCC)OCC.NNc1ncnc2scc(Br)c12>>Brc1csc2ncn3cnnc3c12,,CCO,,CCOC(C)=O,,test
US20090170791A1,C=CCc1ccc2c(c1)c(=O)c(C(=O)OCC)cn2CC>>C=CCc1ccc2c(c1)c(=O)c(C(=O)O)cn2CC,,C1CCOC1,,[Na+].[OH-],,test
US20160083400A1,CCOC(=O)c1noc(C2CCCC2)c1NC(=O)NC(=O)c1ccccc1>>O=c1[nH]c(=O)c2noc(C3CCCC3)c2[nH]1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20070135405A1,COC(=O)C1=C(c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)CC2CCC1N2C(=O)OC(C)(C)C>>Cc1cc(Cl)c(OCCOc2ccc(C3=C(C(=O)O)C4CCC(C3)N4C(=O)OC(C)(C)C)cc2)c(Cl)c1,,CCO,,[Na+].[OH-],,test
US07226925B2,CC(C)N(C)CCO.Clc1ncccc1OCCOC1CCCCO1>>CC(C)N(C)CCOc1ncccc1OCCO,,Cc1ccccc1,,CC(C)(C)O,CC(C)(C)[O-].[K+],test
US20040102450A1,N#CCN1CCN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CC1.S>>NC(=S)CN1CCN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CC1,,CCO,,CCN(C(C)C)C(C)C,,test
US07351743B1,CCC(C)c1ccc(N(C)C#N)cc1.CCC(C)c1ccc(NC)cc1.Cl>>CCC(C)c1ccc(N(C)C(=N)N(C)c2ccc(C(C)CC)cc2)cc1.Cl,,Clc1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100179211A1,CC(C)(C)OC(=O)N1CCC(O)(c2cc(F)cc(F)c2)C1>>OC1(c2cc(F)cc(F)c2)CCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050203091A1,C[Si](C)(C)CCOCn1nc(C=Cc2ccccc2)c2cnc(Oc3ccc(F)cc3F)nc21>>Fc1ccc(Oc2ncc3c(C=Cc4ccccc4)n[nH]c3n2)c(F)c1,,CCOCC,CO,Cl,,test
US20060052599A1,Cl.O=C(/C=C/c1ccc(N[C@@H]2CCN(C(=O)c3ccc(Cl)cc3)C2)nc1)NOC1CCCCO1>>Cl.O=C(/C=C/c1ccc(N[C@@H]2CCN(C(=O)c3ccc(Cl)cc3)C2)nc1)NO,,CCOC(C)=O,CO,,,test
US20160024095A1,Cc1cnc(-c2cc(Cl)ncc2Cl)c(C)c1.O=C(Nc1cn2c(n1)CNCC2)C(F)(F)F>>Cc1cnc(-c2cc(N3CCn4cc(NC(=O)C(F)(F)F)nc4C3)ncc2Cl)c(C)c1,,CS(C)=O,,[Cs+].[F-],,test
US20060154975A1,CCOCc1csc(NC(C)=O)n1>>CCOCc1csc(N)n1,,C1CCOC1,,Cl,,test
US20120088750A1,CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)OCC)CC4)nc3)cc(C(=O)NCC)c2s1>>CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)O)CC4)nc3)cc(C(=O)NCC)c2s1,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20020193407A1,CC#CC(=O)CC.CCNN>>CCc1cc(C)n(CC)n1,,CCCCO,O,,,test
US20100022527A1,C=CS(=O)(=O)Nc1cccc(-c2cc(C)c(C3=C(O)C4(CCCCC4)OC3=O)cc2Cl)c1.CNC>>Cc1cc(-c2cccc(NS(=O)(=O)CCN(C)C)c2)c(Cl)cc1C1=C(O)C2(CCCCC2)OC1=O,,CCO,,,,test
US20070254908A1,CC(C)(C)OC(=O)CBr.CCCCc1nc(-c2ccc(C(F)(F)F)cc2)sc1Cn1ccc2cc(O)cnc21>>CCCCc1nc(-c2ccc(C(F)(F)F)cc2)sc1Cn1ccc2cc(OCC(=O)O)cnc21,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US08304419B2,CC(C)(C)N(Cc1ccc(Cl)c(Oc2cc(C#N)cc(C(F)F)c2)c1F)C(=O)[O-].O=C(O)C(F)(F)F>>N#Cc1cc(Oc2c(Cl)ccc(CN)c2F)cc(C(F)F)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20070197598A1,C[C@H](NC1=NC(=O)C(C)(CCCNC2CC2)S1)c1ccccc1C(F)(F)F.O=C(O)c1ccoc1>>C[C@H](NC1=NC(=O)C(C)(CCCN(C(=O)c2ccoc2)C2CC2)S1)c1ccccc1C(F)(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20140213592A1,CCOC(=O)c1ccn2cnnc2c1.O=C1CCC(=O)N1Br>>CCOC(=O)c1ccn2c(Br)nnc2c1,,ClC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US20060041128A1,CC(C)(C)OC(=O)NCCC=O.Cc1noc2nc(C(N)C(C)C)n(Cc3cccc(F)c3)c(=O)c12>>Cc1noc2nc(C(NCCCNC(=O)OC(C)(C)C)C(C)C)n(Cc3cccc(F)c3)c(=O)c12,CC(=O)O,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05705662,C/C(=C\[C@H]1CC[C@]2(O)[C@@H]3CC[C@@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)CO>>C/C(C=O)=C\[C@H]1CC[C@]2(O)[C@@H]3CC[C@@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,O=[Mn]=O,ClC(Cl)Cl,,,,test
US20020169317A1,N#CCBr.Oc1c(Cl)ccc2c1c1cccc3c1n2C(c1ccccc1)CO3>>N#CCOc1c(Cl)ccc2c1c1cccc3c1n2C(c1ccccc1)CO3,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020016506A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COS(=O)(=O)OC.Nc1ccccc1[N+](=O)[O-]>>CN(C(=O)OC(C)(C)C)c1ccccc1[N+](=O)[O-],,C1CCOC1,Cc1ccccc1,[H-].[Na+],,test
US20050038035A1,CC(=O)Nc1cccc(CCCc2ccc(NC(=O)c3ccc(C)cc3-c3ccc(C(F)(F)F)cc3)cc2)n1>>Cc1ccc(C(=O)Nc2ccc(CCCc3cccc(N)n3)cc2)c(-c2ccc(C(F)(F)F)cc2)c1,,CO,,Cl,,test
US20090036443A1,COC(=O)c1cc2[nH]c(-c3ccc(Cl)cc3)c(C3=CCCCC3)c2s1>>COC(=O)c1cc2[nH]c(-c3ccc(Cl)cc3)c(C3CCCCC3)c2s1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20110218192A1,CC(=O)N1CCC2(CC1)CC(=O)c1cc(-c3cccc(C#N)c3)ccc1O2.C[Si](C)(C)N=C=N[Si](C)(C)C>>CC(=O)N1CCC2(CC1)CC(=NC#N)c1cc(-c3cccc(C#N)c3)ccc1O2,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20060293340A1,Cc1ccc(N)cc1Nc1nccc(-c2cnccn2)n1.O=C(O)c1cccc(OCC(F)(F)F)c1>>Cc1ccc(NC(=O)c2cccc(OCC(F)(F)F)c2)cc1Nc1nccc(-c2cnccn2)n1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20090029947A1,COc1ccc([C@@H]2CC[C@]3(COC(=O)N3)C2)cc1>>O=C1N[C@@]2(CC[C@@H](c3ccc(O)cc3)C2)CO1,,ClCCl,,BrB(Br)Br,,test
US06544984B1,CC#CCO.COC(=O)C1CN(C(=O)c2ccccc2)c2ccccc2CN1S(=O)(=O)c1ccc(O)cc1>>CC#CCOc1ccc(S(=O)(=O)N2Cc3ccccc3N(C(=O)c3ccccc3)CC2C(=O)OC)cc1,,C1CCOC1,Cc1ccccc1,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090306063A1,CC[C@@H](c1ccccc1)N1Cc2cc3c(cc2C[C@H]1C(=O)N[C@@H](Cc1ccc(-c2ccc(C#N)cc2)cc1)C(=O)OC)N(C)C(=O)[C@@H](c1ccc(O)cc1)O3.Clc1ccc(CBr)cc1Cl>>CC[C@@H](c1ccccc1)N1Cc2cc3c(cc2C[C@H]1C(=O)N[C@@H](Cc1ccc(-c2ccc(C#N)cc2)cc1)C(=O)OC)N(C)C(=O)[C@@H](c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1)O3,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20130317001A1,CC(C)(C)OC(=O)c1cc(Cl)c(F)cc1F.OC1CCC2(CC1)OCCO2>>CC(C)(C)OC(=O)c1cc(Cl)c(OC2CCC3(CC2)OCCO3)cc1F,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20130116235A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cn1cc(Br)nc(Nc2cccnc2)c1=O>>Cn1cc(B(O)O)nc(Nc2cccnc2)c1=O,[Pd],C1COCCO1,,CC(=O)[O-].[K+],,test
US20060084663A1,CS(=O)(=O)Cl.Cc1nc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)sc1CO>>Cc1nc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)sc1CCl,,ClCCl,,CCN(CC)CC,,test
US05789409,C1CN(C2CNCCN2)CCN1.C1COCCO1.COC(=O)Cc1ccc(CBr)cc1.Cl>>Cl.O=C(O)Cc1ccc(CN2CCN(c3ccccn3)CC2)cc1,,C1COCCO1,,CCN(CC)CC,,test
US20020103253A1,CC(C)C(Cl)=CC#N.COC(=O)CS>>COC(=O)c1sc(C(C)C)cc1N,,CO,,C[O-].[Na+],,test
US20140155391A1,C1COCCN1.C=CS(=O)(=O)Nc1cc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)ccc1OC>>COc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1NS(=O)(=O)CCN1CCOCC1,,C1CCOC1,O,,,test
US20140135332A1,CCOC(=O)CC(N)=S.O=C(CBr)c1ccc(Cl)cc1>>CCOC(=O)Cc1nc(-c2ccc(Cl)cc2)cs1,,CCO,,,,test
US20130072535A1,CONC(CF)Cc1c(Cl)cc(Cl)cc1Cl.Cn1cc(C(=O)Cl)c(C(F)(F)F)n1>>CON(C(=O)c1cn(C)nc1C(F)(F)F)C(CF)Cc1c(Cl)cc(Cl)cc1Cl,,ClCCl,,CCN(CC)CC,,test
US05444080,CCCCc1ncc(CO)n1Cc1ccccc1Cl>>CCCCc1ncc(C=O)n1Cc1ccccc1Cl,,ClCCl,,,,test
US20050004134A1,CC(C)N.CCOC(=O)c1nc(-c2ccccc2)c(-c2ccc(=O)n(Cc3ccccc3)n2)s1>>CC(C)NC(=O)c1nc(-c2ccccc2)c(-c2ccc(=O)n(Cc3ccccc3)n2)s1,,C1CCOC1,,,,test
US20100222303A1,CCOC(CN(Cc1cccc2scnc12)C(=O)C(Cc1ccc(OC(C)(C)C)cc1)NC(=O)CC(C)NC(=O)NCc1ccccc1)OCC>>CC1CC(=O)N2C(Cc3ccc(O)cc3)C(=O)N(Cc3cccc4scnc34)CC2N1C(=O)NCc1ccccc1,,O=CO,,,,test
US20050234065A1,CC(C)(C)OC(=O)N[C@H](C(=O)N1CCCC1)[C@@H]1CC[C@@H](N)CC1.O=C(Cl)c1nccnc1Cl>>CC(C)(C)OC(=O)N[C@H](C(=O)N1CCCC1)[C@@H]1CC[C@@H](NC(=O)c2nccnc2Cl)CC1,,CCOC(C)=O,ClCCl,,,test
US20050176751A1,CCOCCn1cc(C2CCN(C(=O)OCC)CC2)c2cccnc21>>CCOCCn1cc(N2CCCCC2)c2cccnc21,,CC(C)O,,[K+].[OH-],,test
US20100120798A1,CC1(C)CCN(c2cccc(NC(=O)C3(NC(=O)OCC4c5ccccc5-c5ccccc54)CCN(C(=O)OCC4c5ccccc5-c5ccccc54)CC3)c2)CC1>>CC1(C)CCN(c2cccc(NC(=O)C3(N)CCNCC3)c2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20160145247A1,Nc1cc(CO)cc(Br)c1F.O=CC1CCCO1>>OCc1cc(Br)c(F)c(NCC2CCCO2)c1,,ClCCCl,,[Cl-].[NH4+],,test
US20110144105A1,COCCBr.CS(=O)(=O)c1ccc(C(=CC2CCCC2)c2cc3cc(O)cnc3n2S(=O)(=O)c2ccccc2)cc1>>COCCOc1cnc2c(c1)cc(C(=CC1CCCC1)c1ccc(S(C)(=O)=O)cc1)n2S(=O)(=O)c1ccccc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20150266895A1,CCN(C(=O)OC(C)(C)C)c1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(N)ncc12.CC[SiH](CC)CC.O=C(n1ccnc1)n1ccnc1.c1c[nH]cn1>>CCNc1n[nH]c2cc(NC(=O)NC(CC)c3ccccn3)ncc12,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20070290199A1,CC(=O)c1ccc(Br)cc1.CCOC(=O)c1ccc(Br)cc1>>O=C(CC(=O)c1ccc(Br)cc1)c1ccc(Br)cc1,,CCOCC,,C[O-].[Na+],,test
US20040058888A1,CC(=O)N[C@H]1[C@@H](OCc2ccccc2)O[C@H](CO)[C@@H](O)[C@@H]1OCc1ccccc1.O=C(Cl)c1ccccc1>>CC(=O)N[C@H]1[C@@H](OCc2ccccc2)O[C@H](COC(=O)c2ccccc2)[C@@H](O)[C@@H]1OCc1ccccc1,,ClCCCl,,c1c[nH]cn1,,test
US05556874,CN(C)CCCCl.CSc1[nH]c2ccccc2c1C(=O)NCc1ccccc1>>CSc1c(C(=O)Nc2ccccc2)c2ccccc2n1CCCN(C)C,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US05045552,COCCCCOc1ccnc(CCl)c1.Sc1nc2ccccc2[nH]1>>COCCCCOc1ccnc(CSc2nc3ccccc3[nH]2)c1,,CCO,,[Na+].[OH-],,test
US20060252795A1,CC(C)(C)OC(=O)n1c(CNC2CCCc3cccnc32)nc2ccccc21.N#Cc1ccccc1-c1ccc(CBr)cc1>>NCc1ccccc1-c1ccc(CN(Cc2nc3ccccc3[nH]2)C2CCCc3cccnc32)cc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20160039834A1,Brc1c[nH]c2ncncc12.CS(=O)(=O)Cl>>CS(=O)(=O)n1cc(Br)c2cncnc21,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20060122064A1,CCOC(=O)CCc1ccc(OCC)c(OC)c1>>CCOc1ccc(CCC(=O)O)cc1OC,,CCO,,[Na+].[OH-],,test
US20040037791A1,C=C(C)COc1ccc(C=O)cc1.N#CCS(=O)(=O)c1ccccc1>>C=C(C)COc1ccc(C=C(C#N)S(=O)(=O)c2ccccc2)cc1,,CCO,,C1CCNCC1,,test
US20150031685A1,CN[C@H](CN1CC[C@H](O[Si](C)(C)C(C)(C)C)C1)c1cccc(C(=O)NCC(F)(F)F)c1.O=C(O)Cc1ccc2c(c1)NC(=O)C2>>CN(C(=O)Cc1ccc2c(c1)NC(=O)C2)[C@H](CN1CC[C@H](O[Si](C)(C)C(C)(C)C)C1)c1cccc(C(=O)NCC(F)(F)F)c1,,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20060004084A1,O=C(O)CCc1ccc2c(c1)COC2=C1C(=O)Nc2ccc(F)cc21.c1ccc(SSc2ccccn2)nc1>>O=C(CCc1ccc2c(c1)COC2=C1C(=O)Nc2ccc(F)cc21)Sc1ccccn1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20020107273A1,Cc1cc(C)c([N+](=O)[O-])c(Nc2ccc(CCNC(=O)Oc3ccccc3)cc2)n1.Cc1ccc(S(N)(=O)=O)cc1>>Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(Nc3nc(C)cc(C)c3[N+](=O)[O-])cc2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US04818807,BrCCCCCCCCCCCCBr.O=C(OCc1ccccc1)c1ccc(O)cc1>>O=C(OCc1ccccc1)c1ccc(OCCCCCCCCCCCCBr)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04614614,C=CCN1CN(CC=C)CN(CC=C)C1.Cl.Sc1ccccc1>>C=CC[NH2+]CSc1ccccc1.[Cl-],,CCOCC,,,,test
US20020022631A1,CC[C@H](O)[C@@H](Cc1ccncc1)NC(=S)NC(C)(C)C>>CCNC1=NC(Cc2ccncc2)CS1,,Cl,,,,test
US04524148,C1CCCCC1.CC1CCc2c(Br)c(F)cc3c(=O)c(C(=O)O)cn1c23.CN(C)C=O>>CC1CCc2c(Br)c(F)cc3c(=O)c(C(=O)OCCN(C)C)cn1c23,CN(C)C=O,C1CCCCC1,,O=S(Cl)Cl,,test
US20140221361A1,C=C(CN(C)C(=O)CCC(=O)OC)[C@@H]1CC[C@]2(C(=O)NCCC(=O)OCC)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC(C)(C)C)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(CN(C)C(=O)CCC(=O)OC)[C@@H]1CC[C@]2(C(=O)NCCC(=O)OCC)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140296313A1,CCOC(=O)C(C)C1(NC(=O)OCc2ccccc2)COC1>>CC(C(=O)O)C1(NC(=O)OCc2ccccc2)COC1,,CO,,[Na+].[OH-],,test
US20050065150A1,CCOC(=O)CCC(C)(OC)OC.Cc1c(OCc2ccccc2)cc(CO)c(O)c1C>>CCOC(=O)CCC1(C)OCc2cc(O)c(C)c(C)c2O1,,CN(C)C=O,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20040006123A1,CCOC(=O)c1c(N)c2ccc(Cl)cc2n1C(C)=O>>CCOC(=O)c1[nH]c2cc(Cl)ccc2c1N,,O,,[K+].[OH-],,test
US20150210699A1,CC(C)(C)OC(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1.Cl>>Cl.Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2[C@@H]1CCCNC1,,C1COCCO1,CCOCC,,,test
US20040058903A1,CC(=O)N(CCc1ccccn1)c1ccc([N+](=O)[O-])cc1>>CC(=O)N(CCc1ccccn1)c1ccc(N)cc1,[Pd],C1CCOC1,CO,,,test
US20040102626A1,N#Cc1c(N)nc(S)c(C#N)c1-c1ccc2c(c1)OCC(CO)O2.OCCBr>>N#Cc1c(N)nc(SCCO)c(C#N)c1-c1ccc2c(c1)OCC(CO)O2,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20100298168A1,O=C(O)c1ccc(C(OCCCc2ccccc2)(c2ccccc2)c2cccc(OCCO)c2)cc1.O=C1CCC(=O)N1O>>O=C(ON1C(=O)CCC1=O)c1ccc(C(OCCCc2ccccc2)(c2ccccc2)c2cccc(OCCO)c2)cc1,CN(C)c1ccncc1,C1CCOC1,CCOCC,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05776983,COc1ccc(CC(=O)Cl)cc1.c1ccccc1>>COc1ccc(CC(=O)c2ccccc2)cc1,,c1ccccc1,,,,test
US20120015052A1,COC(=O)c1ccc2c(-c3ccccc3Cl)nn(-c3ccc(C)cc3)c2c1>>Cc1ccc(-n2nc(-c3ccccc3Cl)c3ccc(C(=O)O)cc32)cc1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20070054887A1,CC(C)(O)CCC[C@@H](CO)[C@H]1CC[C@H]2[C@@H](O[Si](C)(C)C(C)(C)C)CCC[C@]12C.c1ccc(Sc2ccccc2)cc1>>CC(C)(O)CCC[C@@H](CSc1ccccc1)[C@H]1CC[C@H]2[C@@H](O[Si](C)(C)C(C)(C)C)CCC[C@]12C,,Cc1ccccc1,c1ccncc1,CCCCP(CCCC)CCCC,,test
US20080096877A1,CC(=O)OC(C)=O.CN(c1cccc2cc(C3=NCC(CN)S3)[nH]c12)S(=O)(=O)c1cccs1>>CC(=O)NCC1CN=C(c2cc3cccc(N(C)S(=O)(=O)c4cccs4)c3[nH]2)S1,,CC(=O)N(C)C,,O,,test
US20010007031A1,COc1cc(NC(C)CCCN2C(=O)c3ccccc3C2=O)c2nccc(C)c2c1Oc1ccc(Cl)c(Cl)c1>>COc1cc(NC(C)CCCN)c2nccc(C)c2c1Oc1ccc(Cl)c(Cl)c1,,CCO,,,,test
US06121285,CCOC(=O)C1([C@H]2CN([C@@H](C)c3ccccc3)C(=O)[C@H]2F)CC1>>C[C@@H](c1ccccc1)N1C[C@H](C2(C(=O)O)CC2)[C@H](F)C1=O,,CCO,,[Na+].[OH-],,test
US20040138273A1,NCCNc1ccc([N+](=O)[O-])c(N)n1.O=[N+]([O-])c1ccc(F)cc1-c1ccc(Cl)cc1Cl>>Nc1nc(NCCNc2ccc([N+](=O)[O-])c(-c3ccc(Cl)cc3Cl)c2)ccc1[N+](=O)[O-],,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US06258775B1,C=C(c1cccc(C(=O)OC)c1)c1cc2c(cc1C)C(C)(C)CCC2(C)C>>COC(=O)c1cccc(C(C)c2cc3c(cc2C)C(C)(C)CCC3(C)C)c1,[Pd],CCOC(C)=O,,[H][H],,test
US20100286118A1,COCCCOS(C)(=O)=O.O=c1[nH]c2cc(Br)ccc2o1>>COCCCn1c(=O)oc2ccc(Br)cc21,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20050130958A1,Cc1ccc(S(=O)(=O)N2CCSC[C@H]2C(=O)O)cc1.OCCCc1cccnc1>>Cc1ccc(S(=O)(=O)N2CCSC[C@H]2C(=O)OCCCc2cccnc2)cc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20160222047A1,C=O.COC1(c2ccc(C)c(Cc3ccc4c(c3)OCCO4)c2)O[C@H](C=O)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>COC1(c2ccc(C)c(Cc3ccc4c(c3)OCCO4)c2)OC(CO)(CO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,,C1COCCO1,,[K+].[OH-],,test
US20090247530A1,CN(C)CC1(Cc2ccccc2)CCC(=O)CC1.CNC.[C-]#N>>CN(C)CC1(Cc2ccccc2)CCC(C#N)(N(C)C)CC1,,CO,O,Cl,,test
US20110311474A1,CC1CC(N(Cc2ccccc2)Cc2ccccc2)CC1c1cnc2cnc3[nH]ccc3n12.C[Si](C)(C)CCOCCl>>CC1CC(N(Cc2ccccc2)Cc2ccccc2)CC1c1cnc2cnc3c(ccn3COCC[Si](C)(C)C)n12,,CN(C)C=O,,[H-].[Na+],,test
US20040176416A1,O=C1NC2CCC1C(O)C2>>OC1CC2CCC1CN2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150291577A1,CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1csc(C(=O)NC2CCC(F)(F)CC2)c1.Cl>>Cl.N[C@@H]1C[C@H]1c1csc(C(=O)NC2CCC(F)(F)CC2)c1,,CCOC(C)=O,,,,test
US20090239864A1,C1COCCN1.C[C@H](c1ccccc1)N1CCO[C@@H](c2ccc(C(=O)O)cc2)C1>>C[C@H](c1ccccc1)N1CCO[C@@H](c2ccc(C(=O)N3CCOCC3)cc2)C1,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20100021423A1,COc1c([N+](=O)[O-])cc(Br)cc1C(C)(C)C.COc1ncccc1B(O)O>>COc1ncccc1-c1cc([N+](=O)[O-])c(OC)c(C(C)(C)C)c1,,CO,ClCCl,O=C([O-])[O-].[Na+].[Na+],,test
US20160046653A1,CCCCCc1ccco1.CC[SiH](CC)CC>>CCCCCc1ccc([Si](CC)(CC)CC)o1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US04218479,COc1ccc(CCN)c(OC)c1OC.O=CC(=O)c1ccccc1OCc1ccccc1>>COc1ccc(CCN=C(OCc2ccccc2)C(=O)c2ccccc2)c(OC)c1OC,,CS(C)=O,,O,,test
US20070105896A1,C1=C(n2ccnc2)C2CCN1CC2>>c1cn(C2CN3CCC2CC3)cn1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20140010783A1,N#Cc1c(Cl)cc([N+](=O)[O-])cc1Cl>>N#Cc1c(Cl)cc(N)cc1Cl,[Fe],CO,,O,[Cl-].[NH4+],test
US20100143978A1,CCOC(CBr)OCC.O=C([O-])c1ccccc1>>CCOC(COCc1ccccc1)OCC,,O,,CN(C)C=O,,test
US20110190316A1,COC(=O)c1ccc(-c2ccc(Cl)cc2Cl)nc1Cl.Cl.Nc1nc(NC2CCCNC2)ccc1C(=O)C(F)(F)F>>COC(=O)c1ccc(-c2ccc(Cl)cc2Cl)nc1N1CCCC(Nc2ccc(C(=O)C(F)(F)F)c(N)n2)C1.Cl,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US20040116438A1,CC(C)(C)OC(=O)NCCC=O.CC(C)C(N)c1nc2nccnc2c(=O)n1Cc1ccccc1>>CC(C)C(NCCCNC(=O)OC(C)(C)C)c1nc2nccnc2c(=O)n1Cc1ccccc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05051361,Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)n(CCCN2C(=O)c3ccccc3C2=O)c1=O>>Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)n(CCCN)c1=O,,CO,,NN,O,test
US20130102576A1,O=C(CBr)OCc1ccccc1.O=[N+]([O-])c1ccc2c(c1)CCN2>>O=C(CN1CCc2cc([N+](=O)[O-])ccc21)OCc1ccccc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US03954834,CCCCCCC1C(=O)CCC1C(=O)O.CCO>>CCCCCCC1C(=O)CCC1C(=O)OCC,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20060074102A1,N#Cc1c(Br)cncc1Br.NN>>Nc1n[nH]c2cncc(Br)c12,,CO,,O,,test
US04309211,CCOC(=O)C(C)Br.Oc1ccc(Sc2nnc3cc(Cl)ccc3n2)cc1>>CCOC(=O)C(C)Oc1ccc(Sc2nnc3cc(Cl)ccc3n2)cc1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05624937,Clc1ccc2ccccc2n1.O=[N+]([O-])c1ccc(S)cc1>>O=[N+]([O-])c1ccc(Sc2ccc3ccccc3n2)cc1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20150087663A1,CC[C@H](NC(=O)OC(C)(C)C)C(=O)O.O=C1CCC(=O)N1O>>CC[C@H](NC(=O)OC(C)(C)C)C(=O)ON1C(=O)CCC1=O,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20160257670A1,CC(C)(C)OC(=O)N1CCC(O)(C(=O)O)CC1.N#Cc1ccc(N)nc1>>CC(C)(C)OC(=O)N1CCC(O)(C(=O)Nc2ccc(C#N)cn2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150175601A1,CC(C)(C)OC(=O)Nc1c(C(=O)O)ccnc1-c1cccc([N+](=O)[O-])c1>>Nc1c(C(=O)O)ccnc1-c1cccc([N+](=O)[O-])c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150322002A1,CS(=O)(=O)Cl.OCc1cc(F)c(Br)cc1Cl>>CS(=O)OCc1cc(F)c(Br)cc1Cl,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20080306125A1,COC(=O)c1c(C)n(C(C)C)c2cc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3C)ccc12>>Cc1cc(OCc2c(-c3c(Cl)cccc3Cl)noc2C(C)C)ccc1-c1ccc2c(C(=O)O)c(C)n(C(C)C)c2c1,,CO,,Cl,[Na+].[OH-],test
US20130303515A1,Cc1cc(C)cc(CC(=O)N2CCC2(C)C(=O)N(CC(=O)O)Cc2ccc(Cl)cc2)c1.NS(=O)(=O)C(F)(F)F>>Cc1cc(C)cc(CC(=O)N2CCC2(C)C(=O)N(CC(=O)NS(=O)(=O)C(F)(F)F)Cc2ccc(Cl)cc2)c1,CN(C)c1ccncc1,CN(C)C=O,,CCN=C=NCCCN(C)C,Cl,test
US20030166639A1,Cc1cc(NC(=O)CC(=O)c2cccc(-c3cncnc3)c2)c(NC(=O)OC(C)(C)C)cc1C(F)(F)F>>Cc1cc2c(cc1C(F)(F)F)N=C(c1cccc(-c3cncnc3)c1)CC(=O)N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050124617A1,CC(C)c1ccccc1N=C1NCCS1.CI.S=C=S>>CSC(=S)N1CCSC1=Nc1ccccc1C(C)C,,CN(C)C=O,O,[H-].[Na+],,test
US04868165,CSC(SC)SC.C[C@H](CCC=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C>>CSC(SC)(SC)C(O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,C1CCOC1,CCCCCC,[Li]CCCC,test
US20070244092A1,CC(C)(C)c1nc2cc(S(=O)(=O)N3CC(O)C3)ccc2n1CC1CCC(F)(F)CC1.CCN=C=O>>CCNC(=O)OC1CN(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCC(F)(F)CC2)C1,,ClCCl,,CCN(CC)CC,,test
US04259504,COC(OC)N(C)C.Nc1ccc(-n2ncnc2-c2ccccc2)cc1>>CN(C)C=Nc1ccc(-n2ncnc2-c2ccccc2)cc1,,CN(C)C=O,,,,test
US20120322837A1,Cc1ccc(NC(=O)CC(CC(=O)OC(C)(C)C)c2nnn(C3CC(CC(C)C)C3)c2C2CC2)c(C)c1>>Cc1ccc(NC(=O)CC(CC(=O)O)c2nnn(C3CC(CC(C)C)C3)c2C2CC2)c(C)c1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20110046171A1,CCNC(=NS(=O)(=O)c1cccc(OC)c1)N1CC(C)(C)C=N1>>CCNC(=NS(=O)(=O)c1cccc(O)c1)N1CC(C)(C)C=N1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US05420131,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](C(=O)O)c1ccccc1>>CC(C)(C)OC(=O)N[C@@H](C(=O)O)c1ccccc1,,C1CCOC1,O,[Na+].[OH-],,test
US20120165347A1,CCOC(=O)CC(=O)OCC.Clc1cc(Br)cnc1Cl>>CCOC(=O)C(C(=O)OCC)c1ncc(Br)cc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20030144532A1,CCCC(=O)Cl.OCCO>>CCCC(=O)OCCO,,CCN(CC)CC,,,,test
US20020016322A1,COc1cc(OC)c(CSC(C)(C)CC(=O)O)c(OC)c1.O=C(CCl)CCl>>COc1cc(OC)c(CSC(C)(C)CC(=O)OCC(=O)CCl)c(OC)c1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20120122853A1,CCOC(=O)CCc1nc(-c2ccc(C(F)(F)F)cc2)ccc1N>>O=C1CCc2nc(-c3ccc(C(F)(F)F)cc3)ccc2N1,,CCO,,C,C[O-].[Na+],test
US20070105904A1,C#Cc1ccc(N)nc1N.ON=C(Cl)Cc1ccc(OCc2ccccc2)cc1>>Nc1ccc(-c2cc(Cc3ccc(OCc4ccccc4)cc3)no2)c(N)n1,,C1CCOC1,,CCN(CC)CC,,test
US20140275087A1,COC(=O)CCCN(C(=O)OC(C)(C)C)[C@H]1CN(S(=O)(=O)c2cn(C)cn2)C[C@@H]1c1ccccc1>>Cn1cnc(S(=O)(=O)N2C[C@H](c3ccccc3)[C@@H](N(CCCCO)C(=O)OC(C)(C)C)C2)c1,,ClCCl,,CC(C)C[Al+]CC(C)C.[H-],,test
US20120053173A1,COc1ccc2oc(C(O)C3CCCCC3)c(Br)c2c1.O=S(Cl)Cl>>COc1ccc2oc(C(Cl)C3CCCCC3)c(Br)c2c1,,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US20130079328A1,CC(C)(C)OC(=O)N1CCN(c2ccc(C(=O)O)cn2)CC1.NCc1cnc(-c2ccnc(C(F)(F)F)c2)c(F)c1>>CC(C)(C)OC(=O)N1CCN(c2ccc(C(=O)NCc3cnc(-c4ccnc(C(F)(F)F)c4)c(F)c3)cn2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060235033A1,CC(N)c1ccc(F)cc1.COc1cc2nccc(Oc3ccc(N)cc3OC)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)NC(C)c4ccc(F)cc4)cc3OC)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20140349991A1,CCN=C=O.Cc1c(C2CCNCC2)oc2c(C)c(O)ccc2c1=O>>CCNC(=O)N1CCC(c2oc3c(C)c(O)ccc3c(=O)c2C)CC1,,CN(C)C=O,,,,test
US20050090498A1,CC(=O)OC(=O)c1ccc2c(c1)C(=C1C=Cc3ccccc3N1)C(=O)N2>>O=C1Nc2ccc(C(=O)O)cc2C1=C1C=Cc2ccccc2N1,,CO,,Cl,[Na+].[OH-],test
US20160222028A1,COC(=O)C1CC2(CN(C(=O)OC(C)(C)C)C2)S(=O)(=O)C1>>CC(C)(C)OC(=O)N1CC2(CC(C(=O)O)CS2(=O)=O)C1,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20160096841A1,Cc1ccc(F)c(C(=O)O)c1Cl.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cc1ccc(F)c(N)c1Cl,,C1CCOC1,,O,,test
US04962115,COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(CCCOc2ccc(F)cc2)C[C@H]1OC>>COc1ccccc1C(N)=O,,CO,,O,,test
US20150087585A1,BrCCBr.COC(=O)Cc1cc(C)no1>>COC(=O)C1(c2cc(C)no2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20120028938A1,COC(=O)Cc1c(C)nn(Cc2ccc([N+](=O)[O-])cc2)c1C>>COC(=O)Cc1c(C)nn(Cc2ccc(N)cc2)c1C,[Pd],CO,,,,test
US20070249670A1,CCOC(=O)C[C@H](NC(=O)c1ccc(-c2ccc(OC)cc2)cc1N)C(=O)OCc1ccccc1.Cc1cc(C)c(N=C=O)c(C)c1>>CCOC(=O)C[C@H](NC(=O)c1ccc(-c2ccc(OC)cc2)cc1NC(=O)Nc1c(C)cc(C)cc1C)C(=O)OCc1ccccc1,,c1ccncc1,,,,test
US20090247746A1,N#Cc1cc2cccc(NS(=O)(=O)c3cccs3)c2[nH]1.NCCS>>O=S(=O)(Nc1cccc2cc(C3=NCCS3)[nH]c12)c1cccs1,,O,,CCO,,test
US06723716B1,CC(C)(C)OC(=O)NCCS.O=C(CCl)CCl>>CC(C)(C)OC(=O)NCCSCC(=O)CCl,,C1CCOC1,,CCN(CC)CC,,test
US20040132769A1,Nc1cc(F)cc(F)c1.O=C1CCC(=O)N1Br>>Nc1cc(F)c(Br)c(F)c1,,CCOCC,CN(C)C=O,,,test
US20020038025A1,C=CCN(C)CCCCCCOc1ccc(N(C)C(=O)OC(C)(C)C)cc1>>C=CCN(C)CCCCCCOc1ccc(NC)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090042929A1,O=C(CBr)C12CC3CC(CC(C3)C1)C2.SCc1ccc(Cl)cc1>>O=C(CSCc1ccc(Cl)cc1)C12CC3CC(CC(C3)C1)C2,,CC#N,CCN(CC)CC,,,test
US20110071126A1,BrCCc1ccccc1CCBr.O=C1CCc2ccc(Br)cc21>>O=C1c2cc(Br)ccc2CC12CCc1ccccc1CC2,,C1CCOC1,,[H-].[Na+],,test
US20030013875A1,CC(=O)c1cccc([N+](=O)[O-])c1.NN>>CC(=NN)c1cccc([N+](=O)[O-])c1,,O,,,,test
US20060229447A1,CCOC(=O)C[C@H](Cc1cc(Br)c2[nH]ncc2c1COC(C)=O)C(=O)OCC.O=C1CCC(=O)N1Br>>CCOC(=O)C[C@H](Cc1cc(Br)c2[nH]nc(Br)c2c1COC(C)=O)C(=O)OCC,,ClCCl,,,,test
US20100240638A1,C=C[C@@H]1C[C@]1(NC(=O)OC(C)(C)C)C(=O)NS(=O)(=O)c1ccccc1NCCOCCOCCC(=O)OC>>C=C[C@@H]1C[C@]1(N)C(=O)NS(=O)(=O)c1ccccc1NCCOCCOCCC(=O)OC,,ClCCl,,O=C(O)C(F)(F)F,,test
US05576322,NO.O=Cc1nc(NCc2ccc3c(c2)OCO3)c2cc(Cl)ccc2n1>>ON=Cc1nc(NCc2ccc3c(c2)OCO3)c2cc(Cl)ccc2n1,,CCO,,Cl,[Na+].[OH-],test
US20060025383A1,CN.COC(=O)CN(C(=O)CCl)[C@@H]1CC[C@H](n2cc(I)c3c(Cl)ncnc32)CC1>>CN1CC(=O)N([C@@H]2CC[C@H](n3cc(I)c4c(Cl)ncnc43)CC2)CC1=O,,C1CCOC1,,,,test
US20160083357A1,CCOC(=O)C(C)(C)Br.O=c1[nH]nnn1-c1cccc(F)c1>>CCOC(=O)C(C)(C)n1nnn(-c2cccc(F)c2)c1=O,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04150131,CCOC(=O)Nc1cc(N2CCCCC2)nc(NC(=O)OCC)[n+]1[O-]>>CCOC(=O)Nc1cc(N2CCCCC2)nc2nc(=O)on12,,Cc1ccccc1,,,,test
US05585385,CI.CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(-c2ccc(F)cc2)c2c(c(=O)n1C)CCCN2>>CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(-c2ccc(F)cc2)c2c(c(=O)n1C)CCCN2C,,C1CCOC1,,CCOC(C)=O,[H-].[Na+],test
US20090227584A1,O=[N+]([O-])c1cccc2nc(N[C@@H]3CCc4ccccc43)ccc12>>Nc1cccc2nc(N[C@@H]3CCc4ccccc43)ccc12,[Pd],CCO,,[H][H],,test
US20100286152A1,CC[Al](C#N)CC.CN1CCNCC1.O=Cc1cccnc1>>CN1CCN(C(C#N)c2cccnc2)CC1,,CC(Cl)Cl,O,Cc1ccccc1,,test
US20080167287A1,COC(=O)c1ccc(Br)cc1CBr.NC1CC1>>O=C1c2ccc(Br)cc2CN1C1CC1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20140091283A1,Brc1ccc(Br)cc1.CCCCC(C)=O>>CCCCC(C)(O)c1ccc(Br)cc1,,C1CCOC1,,[Li]CCCC,,test
US05160365,CC(C)OC(=O)c1ccccc1S(=O)(=O)N=C=O.COc1nc(N)nc(C(F)(F)F)n1>>COc1nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)OC(C)C)nc(C(F)(F)F)n1,,ClCCCl,,,,test
US06613942B1,CCOC(=O)C=Cc1ccc(C2OCCO2)c2ccccc12>>CCOC(=O)CCc1ccc(C2OCCO2)c2ccccc12,[Pd],CCOC(C)=O,,,,test
US20050107616A1,CC(C)(C)[C@@H](O)Cc1nnc(-c2ccccc2)o1.CCCC[C@H](N=C=O)C(=O)OC>>CCCC[C@H](NC(=O)O[C@@H](Cc1nnc(-c2ccccc2)o1)C(C)(C)C)C(=O)OC,,Cc1ccccc1,,,,test
US20120238599A1,CCOC(=O)c1c(O)c(C)c(=O)n(C)c1Nc1ccc(I)cc1F.COS(=O)(=O)OC>>CCOC(=O)c1c(OC)c(C)c(=O)n(C)c1Nc1ccc(I)cc1F,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150038574A1,CC1=C(C=O)C(C)(C)CCC1.FC(F)(F)c1cccc(CBr)c1>>CC1=C(C(O)Cc2cccc(C(F)(F)F)c2)C(C)(C)CCC1,,CCOCC,,[Mg],,test
US20030225106A1,CCN(C(C)C)C(C)C.ClCCl.Nc1ccc(Cl)cc1.O=C(O)c1cccs1.On1nnc2ccccc21>>O=C(Nc1ccc(Cl)cc1)c1sccc1NCc1ccncc1,,ClCCl,,ClCCCl,,test
US20140323468A1,COc1ccncc1-c1cnc2c(c1)CCCN2C(=O)OC(C)(C)C>>COc1ccncc1-c1cnc2c(c1)CCCN2,,ClCCl,O=C(O)C(F)(F)F,,,test
US20070054916A1,CC(C)(C)OC(=O)NC1CCNC1.Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2nc(Cl)ncc2c1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2nc(N3CCC(NC(=O)OC(C)(C)C)C3)ncc2c1,,CC(Cl)Cl,ClCCl,CCN(C(C)C)C(C)C,,test
US04654348,CCOC(=O)C(C)(C)Br.Oc1c2ncnc(S)c2nn1-c1ccccc1>>CCOC(=O)C(C)(C)Sc1ncnc2c(O)n(-c3ccccc3)nc12,,O,,CCO,O=C([O-])[O-].[K+].[K+],test
US20150322041A1,CSc1ccnc(Cl)c1C#N.C[C@@H]1CC[C@@H](O)CN1C(=O)c1ccccc1-n1nccn1>>CSc1ccnc(O[C@@H]2CC[C@@H](C)N(C(=O)c3ccccc3-n3nccn3)C2)c1C#N,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20130178500A1,CC(C)(C[C@@H](CC(=C=O)N1CC[C@H]2CN(C(=O)C3(C#N)CC3)C[C@H]21)Cc1cc(F)c(F)cc1F)OC(N)=O.OO>>CC(C)(C[C@@H](CC(=C=O)N1CC[C@H]2CN(C(=O)C3(C(N)=O)CC3)C[C@H]21)Cc1cc(F)c(F)cc1F)OC(N)=O,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160264552A1,CC(C)(C)OC(=O)NC/C=C/C(=O)Nc1ccc(CN2CCC(Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)CC2)cc1.O=C(O)C(F)(F)F>>O=C(/C=C/CNC(=O)C(F)(F)F)Nc1ccc(CN2CCC(Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)CC2)cc1,,ClCCl,,Cl,,test
US20130131018A1,CC(C)(C)CBr.COc1cc(C=O)cc(OC)c1O>>COc1cc(C=O)cc(OC)c1OCC(C)(C)C,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20040126812A1,COc1ccc(C2C(CCC(O)c3ccccc3)C(=O)N2c2ccc(NC(=O)CCCCN(C(=O)OCC3c4ccccc4-c4ccccc43)c3ccccc3)cc2)cc1>>COc1ccc(C2C(CCC(O)c3ccccc3)C(=O)N2c2ccc(NC(=O)CCCCN)cc2)cc1,,CN(C)C=O,,CCNCC,,test
US20110275637A1,Cc1cccc(CO)n1.O=C(Cl)N1CCOCC1>>Cc1cccc(COC(=O)N2CCOCC2)n1.Cl,,C1CCOC1,,[H-].[Na+],,test
US20050096322A1,CN(C)c1cccc(C(=O)O)c1.NNc1ccc(Cl)nn1>>CN(C)c1cccc(C(=O)NNc2ccc(Cl)nn2)c1,,O,,C1CCOC1,Cl,test
US20080176829A1,CC(C)(C)OC(=O)N1CCOc2ccc3[nH]ccc3c2C1.O=S(=O)(Cl)c1ccc(Cl)cc1Cl>>O=S(=O)(c1ccc(Cl)cc1Cl)n1ccc2c3c(ccc21)OCCNC3,,CO,N,CN(C)C=O,[H-].[Na+],test
US20130096118A1,Brc1ccc(Br)c2c3c([nH]c12)CCNC3.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>Brc1ccc(Br)c2c3c([nH]c12)CCN(C(c1ccccc1)(c1ccccc1)c1ccccc1)C3,CN(C)c1ccncc1,ClCCl,,,,test
US20150119362A1,COC(=O)C1SCCC1=O.N=C(N)c1cccc(Cl)c1>>Oc1nc(-c2cccc(Cl)c2)nc2c1SCC2,,CCO,,C[O-].[Na+],,test
US20040157804A1,COC(=O)c1c2c(c(OC(c3ccccc3)c3ccccc3)c3ncccc13)C(=O)N(Cc1ccc(F)cc1)C2>>O=C(O)c1c2c(c(OC(c3ccccc3)c3ccccc3)c3ncccc13)C(=O)N(Cc1ccc(F)cc1)C2,,C1CCOC1,,O,[Li+].[OH-],test
US05981529,CC(CBr)c1ccc(F)cc1.CCN(CC)CC>>c1ccc2[nH]ccc2c1,,CN(C)C=O,,[I-].[Na+],,test
US20110152326A1,BrBr.COc1ccc(C)c(C(C)=O)c1>>COc1ccc(C)c(C(=O)CBr)c1,,CC(=O)O,,Br,,test
US20060135714A1,CC(C)(Br)C(=O)Br.CCOC(CCCN)OCC>>CC(C)(Br)C[NH-].CCCC=O,,C1CCOC1,,CCN(CC)CC,,test
US20100075965A1,O=C(Nc1cn2cc(Br)ccc2n1)C(F)(F)F>>Nc1cn2cc(Br)ccc2n1,,COCCOC,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20150351401A1,CO/C=C/c1ccc(-c2ccc(Cl)cc2)cc1Cl>>O=CCc1ccc(-c2ccc(Cl)cc2)cc1Cl,,ClCCl,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],,test
US20050143452A1,Cc1ccc(-c2cccc3c2CC(CN=[N+]=[N-])O3)cc1>>Cc1ccc(-c2cccc3c2CC(CN)O3)cc1,[Pd],,,,,test
US05654326,BrCc1ccccc1.CCc1cc2c([N+](=O)[O-])cccc2[nH]1>>CCc1cc2c([N+](=O)[O-])cccc2n1Cc1ccccc1,,CN(C)C=O,O,CCCCCC,[H-].[Na+],test
US20100173895A1,C[Si](C)(C)CCOCn1c(C(O)Cc2ccccc2)nc(Br)c1Br>>C[Si](C)(C)CCOCn1c(C(=O)Cc2ccccc2)nc(Br)c1Br,,CCOCC,ClCCl,,,test
US20120142676A1,CI.S=C=S.c1ccc2sccc2c1>>CSC(=S)c1cc2ccccc2s1,,CCOCC,O,[Li]CCCC,,test
US20150099719A1,COC(=O)[C@@H]1CCCC[C@H]1C(=O)C(NC(=O)c1cccc(Cl)c1F)c1ccc(Br)cc1>>COC(=O)[C@@H]1CCCC[C@H]1c1oc(-c2cccc(Cl)c2F)nc1-c1ccc(Br)cc1,,Cc1ccccc1,,O=P(Cl)(Cl)Cl,,test
US20010047020A1,CCOC(=O)c1cccc2nc(SCC)n(Cc3ccc(-c4ccccc4-c4nnn[nH]4)cc3)c12>>CCSc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,CO,,[Na+].[OH-],,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.NCc1cccs1>>COc1ccc2nc(NCc3cccs3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US20140336377A1,CC(C)C(=O)Cl.CC(NC(=O)c1ccnc(N)c1)c1ccc(OCC(F)(F)F)nc1>>CC(C)C(=O)Nc1cc(C(=O)NC(C)c2ccc(OCC(F)(F)F)nc2)ccn1,,CC(=O)N(C)C,,c1ccncc1,,test
US20080200535A1,COC(=O)c1ccc(Br)c(C)c1.OB(O)C1=CCCC1>>COC(=O)c1ccc(C2=CCCC2)c(C)c1,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160272584A1,CC(C)(C)OC(=O)Nc1ccc(-c2ccc(O)cc2[N+](=O)[O-])cc1.CN1CCC(O)CC1>>CN1CCC(Oc2ccc(-c3ccc(NC(=O)OC(C)(C)C)cc3)c([N+](=O)[O-])c2)CC1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070225271A1,CC(C)(C)OC(=O)N1CCC(N)CC1.FC(F)(F)c1ccnc(Cl)n1>>CC(C)(C)OC(=O)N1CCC(Nc2nccc(C(F)(F)F)n2)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US05393775,CC(=O)Oc1c(C)c(C)c2c(c1C)CCC(C)(C(=O)Nc1ccccc1)O2>>Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)Nc1ccccc1)O2,,CCO,O,CC(=O)O,[Na+].[OH-],test
US20030008849A1,CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCN1S(=O)(=O)c1ccc(F)cc1>>CCOC(=O)C1CNCCN1S(=O)(=O)c1ccc(F)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110257157A1,CN(C)CC#Cc1cc2c(cc1Cl)NC(=O)Cc1cnc(N)nc1-2>>CN(C)CCCc1cc2c(cc1Cl)NC(=O)Cc1cnc(N)nc1-2,[Ni],C1CCOC1,O,,,test
US20080153812A1,CCN1CCCN(c2ncc(C(=O)OC)cn2)CC1.COc1cc(CCc2cc(N)[nH]n2)cc(OC)c1>>CCN1CCCN(c2ncc(C(=O)Nc3cc(CCc4cc(OC)cc(OC)c4)n[nH]3)cn2)CC1,,Cc1ccccc1,,C[Al](C)C,,test
US20030087916A1,COc1ccc(C=O)c(OC)c1C.O=C(OO)c1cccc(Cl)c1>>COc1ccc(O)c(OC)c1C,,ClCCl,O,Cl,[K+].[OH-],test
US04663344,COc1ccc(CS)cc1.N#Cc1cc(C(F)(F)F)ccc1Cl>>COc1ccc(CSc2ccc(C(F)(F)F)cc2C#N)cc1,,CN(C)C=O,,C[O-].[Na+],,test
US20160060260A1,COC(=O)CCCOc1cccc(Oc2cc3c(cc2NC(=O)C(F)(F)F)n(C)c(=O)n3C)c1>>Cn1c(=O)n(C)c2cc(Oc3cccc(OCCCC(=O)O)c3)c(N)cc21,,O,,[Na+].[OH-],,test
US20050085541A1,Cc1cc([N+](=O)[O-])c2c(c1Oc1ccc(OCc3ccccc3)c(C=C3CCOCC3)c1)CCC2>>Cc1cc(N)c2c(c1Oc1ccc(O)c(CC3CCOCC3)c1)CCC2,[Pd],CCO,CCOC(C)=O,[H][H],,test
US05902803,CNC(=O)Oc1ccc([N+](=O)[O-])cc1.NCc1cccc2c1Cc1c-2[nH]c(=O)c2nccn12>>CNC(=O)NCc1cccc2c1Cc1c-2[nH]c(=O)c2nccn12,,CN(C)C=O,,,,test
US20160159838A1,COc1cc(C)cc(-c2c(O)ccc3ccccc23)c1O.ClP(Cl)Oc1c(-c2ccccc2)cccc1-c1ccccc1>>COc1cc(C)cc2c1op(Oc1c(-c3ccccc3)cccc1-c1ccccc1)oc1ccc3ccccc3c12,,Cc1ccccc1,,CCN(CC)CC,,test
US20090137580A1,COc1cc(N)ncn1.Cn1ccc2ncnc(Oc3ccc(NC(=O)Oc4ccccc4)c(Cl)c3)c21>>COc1cc(NC(=O)Nc2ccc(Oc3ncnc4ccn(C)c34)cc2Cl)ncn1,,CN1CCCC1=O,,c1ccncc1,,test
US20160176864A1,Cc1cc(C(C2CCOCC2)n2c3cc(C(C)(C)O)ccc3c3ncc(-c4c(C)nnn4C)cc32)no1.O=Cc1ccncc1F>>OC(c1ccncc1F)C1CCOCC1,,CC#N,O,O=C(O)C(F)(F)F,,test
US20150336962A1,C[Si](C)(C)CCOCn1ncc(NC(=O)c2cnn3cccnc23)c1-c1cc(Cl)ccc1OC(F)F>>O=C(Nc1c[nH]nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12,,CO,,Cl,,test
US05374638,BrP(Br)Br.COC(=O)C(Oc1c(C)cc(CO)cc1C)c1cccc(Cl)c1>>COC(=O)C(Oc1c(C)cc(CBr)cc1C)c1cccc(Cl)c1,,ClC(Cl)(Cl)Cl,,,,test
US20120157430A1,COc1c(C(C)NC(=O)OC(C)(C)C)cc(Cl)c(C)c1Br>>COc1c(C(C)N)cc(Cl)c(C)c1Br,,O=C([O-])O,[Na+],C1COCCO1,Cl,test
US05364881,CC(C)(C)OC(=O)OC(=O)[O-].CC(C)(C)OC(=O)[C@H](CCCN)NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](CCCNC(=O)OCc1ccccc1)C(=O)OC(C)(C)C,,ClCCl,,,,test
US20070299077A1,CN1CC2CN(Cc3ccccc3)CC2C1>>CN1CC2CNCC2C1,[Pd],CO,,O=C[O-].[NH4+],,test
US04416985,CC(C)(C)C(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@]4(C)C(=O)[C@H]5C[C@H]5[C@H]4[C@@H]3[C@H](Cl)[C@H]3O[C@]32C1>>CC(C)(C)C(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@]4(C)C(=O)[C@H]5C[C@H]5[C@H]4[C@@H]3C=C[C@]2(O)C1,[Zn],C1CCOC1,CC(=O)O,,,test
US04331670,Cc1nc(N)c(Cl)cc1Cl.O=[N+]([O-])c1cc(C(F)(F)F)c(Cl)c([N+](=O)[O-])c1Cl>>Cc1nc(Nc2c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c2[N+](=O)[O-])c(Cl)cc1Cl,,CN(C)C=O,O,Cl,[K+].[OH-],test
US20070078169A1,CN(C)C1CC=C(c2cc(N)cc(F)c2)CC1.O=C(Cl)c1ccc(F)cc1Cl>>CN(C)C1CC=C(c2cc(F)cc(NC(=O)c3ccc(F)cc3Cl)c2)CC1.Cl,,C1COCCO1,,,,test
US05378714,Cl.O=C=Nc1ccccc1.OCCCN1CCC(c2noc3cc(F)ccc23)CC1>>Cl.O=C(Nc1ccccc1)OCCCN1CCC(c2noc3cc(F)ccc23)CC1,,CCOCC,Cc1ccccc1,,,test
US20010051631A1,Cl.O=c1c2cccc3ncc(c(=O)n1CCc1ccc(NS(=O)(=O)C(F)(F)F)cc1)n32>>Cl.O=c1c2cccc3ncc(c(=O)n1CCc1ccc(NS(=O)(=O)C(F)(F)F)cc1)n32,,CO,,,,test
US20070088163A1,CC(C)[C@H]1NC(=O)CC1=O.CCOC(=O)C=C(N)CCc1ccc(F)cc1.O=Cc1ccc(C(=O)NCc2ccco2)cc1>>CCOC(=O)C1=C(CCc2ccc(F)cc2)NC2=C(C(=O)NC2C(C)C)C1c1ccc(C(=O)NCc2ccco2)cc1,,CCO,,N,,test
US06878705B2,CC(O)c1ccccn1.CCN(C(C)C)C(C)C.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CCl)oc21>>CN(Cc1cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c2o1)CC(O)c1ccccn1,,CN(C)C=O,,O,,test
US20100292215A1,CCOC(=O)C1CCC(O)CC1.O=C(OCc1ccccc1)c1ccc(O)cc1>>CCOC(=O)C1CCC(Oc2ccc(C(=O)OCc3ccccc3)cc2)CC1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110301181A1,CCOC(=O)c1c(C(F)(F)F)c(C(F)F)nn1C>>Cn1nc(C(F)F)c(C(F)(F)F)c1C(=O)O,,CO,,[Na+].[OH-],,test
US09115158B2,CS(C)(=O)=O.O=C1Nc2ccccc2C1(c1c[nH]c2ccccc12)C1CNc2ccccc21>>S=C1Nc2ccccc2C1(c1c[nH]c2ccccc12)C1CNc2ccccc21,,O,,,,test
US20130109682A1,CCOC(=O)CC[C@]1(O)C(=O)C[C@H](c2ccncc2[N+](=O)[O-])O[C@@H]1C.NCc1ccccc1>>C[C@H]1O[C@@H](c2ccncc2[N+](=O)[O-])C[C@H]2N(Cc3ccccc3)C(=O)CC[C@@]12O,,ClCCCl,,CC(=O)O,[BH4-].[Na+],test
US04940703,BrCC1CC1.O=C(O)c1c[nH]c2ccccc12>>O=C(O)c1cn(CC2CC2)c2ccccc12,,CC(C)=O,O,[Na+].[OH-],,test
US07442808B2,Fc1ccc(C(F)(F)F)cc1Cl.Oc1ccc2ccoc2c1>>FC(F)(F)c1ccc(Oc2ccc3ccoc3c2)c(Cl)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04772600,CCOC(=O)CCN.Cl.O=[N+]([O-])c1cccnc1Cl>>CCOC(=O)CCNc1ncccc1[N+](=O)[O-].Cl,,CCO,,CCN(CC)CC,,test
US20030134885A1,COCCOCOc1ccc2cc(C(=O)N(C)Cc3cccc(-c4ccc(CC5SC(=O)NC5=O)cc4)c3)ccc2c1>>CN(Cc1cccc(-c2ccc(CC3SC(=O)NC3=O)cc2)c1)C(=O)c1ccc2cc(O)ccc2c1,,C1CCOC1,CO,O,O=S(=O)(O)O,test
US20040014745A1,COC(=O)Cl.O=C(NC1CCNCC1)c1ccc(F)cc1>>COC(=O)N1CCC(NC(=O)c2ccc(F)cc2)CC1,,CCOC(C)=O,ClCCl,O,c1ccncc1,test
US20110269652A1,CCCCCCCCCCCCOCC(CO)(CO)COCCCCCCCCCCCC>>CCCCCCCCCCCCOCC(C=O)(C=O)COCCCCCCCCCCCC,,ClCCl,,CS(C)=O,O=C(Cl)C(=O)Cl,test
US04826862,COC(=O)Nc1nc2cc(C(O)C3CC3)ccc2[nH]1.O=C(n1ccnc1)n1ccnc1>>COC(=O)Nc1nc2cc(C(C3CC3)n3ccnc3)ccc2[nH]1,,C1CCOC1,,,,test
US20100200054A1,O=C(Cl)c1cccc(Br)c1.c1cncc(-c2nn[nH]n2)c1>>Brc1cccc(-c2nnc(-c3cccnc3)o2)c1,,Cc1ccccc1C,,,,test
US20060246551A1,CC(=O)OC(C)=O.CNC1Cc2cccc(-c3c(Cl)cccc3Cl)c2O1>>CC(=O)NCC1Cc2cccc(-c3c(Cl)cccc3Cl)c2O1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US05910504,O=C(Cl)C(Cl)Cl.[N-]=[N+]=NC[C@H]1CN(c2ccc(-n3ccnn3)c(F)c2)C(=O)O1>>O=C(NC[C@H]1CN(c2ccc(-n3ccnn3)c(F)c2)C(=O)O1)C(Cl)Cl,[Ni],C1CCOC1,ClCCl,CCN(CC)CC,,test
US20110052578A1,CC1(c2nc(Br)c(Br)[nH]2)CC1.C[Si](C)(C)CCOCCl>>CC1(c2nc(Br)c(Br)n2COCC[Si](C)(C)C)CC1,,C1CCOC1,,[H-].[Na+],,test
US20150218086A1,CC(C)(C)OC(=O)C[C@@H](Cc1cc(CO)ccc1[N+](=O)[O-])NC(=O)OC(C)(C)C.O=C(Cl)N(CCCl)CCCl>>CC(C)(C)OC(=O)C[C@@H](Cc1cc(COC(=O)N(CCCl)CCCl)ccc1[N+](=O)[O-])NC(=O)OC(C)(C)C,,c1ccncc1,,,,test
US20130281299A1,CC(=O)OCC(=O)CCl.Cc1ccc(S)cc1>>CC(=O)OCC(=O)CSc1ccc(C)cc1,,COC(C)(C)C,,CCN(CC)CC,,test
US20120289551A1,CCCCCC.Cc1ccnc(NC(=O)OC(C)(C)C)c1.O.[Li]CCCC>>Cc1ccc(C(O)Cc2ccnc(NC(=O)OC(C)(C)C)c2)cc1,,CCOC(C)=O,O,C1CCOC1,[Cl-].[NH4+],test
US20140080806A1,Cn1nc(I)c2c(Cl)ncnc21.FC1CNC1>>Cn1nc(I)c2c(N3CC(F)C3)ncnc21,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20160052951A1,C[C@H](CO)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C.II>>C[C@H](CI)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100119726A1,CC(=O)CC(C)=O.COC(CN)OC>>COC(CNC(C)=CC(C)=O)OC,,O,,C1CCOC1,,test
US04661438,COc1ccc2c(c1)[NH+]=C(C)O[TeH]2(Cl)(Cl)Cl.Cl>>COc1ccc2c(c1)[NH2+]C(C)[Te]2.[Cl-],,CO,O,[Na+].[OH-],,test
US20070213331A1,CCOC(=O)c1cc(N[C@@H](C)CC)nc(OC)c1>>CCOC(=O)c1cc(O)nc(N[C@@H](C)CC)c1,,CC#N,,C[Si](C)(C)Cl,[I-].[Na+],test
US05624950,COc1ccccc1CC(=O)N1CC2C(=O)CCC(O)(c3ccccc3OC)C2C1.[Li]C>>COc1ccccc1CC(=O)N1CC2C(C1)C(O)(c1ccccc1OC)CCC2(C)O,,CCOCC,,CCOC(C)=O,[Cl-].[NH4+],test
US20070066821A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(CN3CCOCC3)cc2)CC1.ClCCl.O=C(c1ccc(CN2CCOCC2)cc1)N1CCNCC1>>O=C(c1ccc(CN2CCOCC2)cc1)N1CCN(C2CC2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04093624,CC(=O)Nc1nc(=O)n([C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]2OC(C)=O)s1>>CC(=O)Nc1nc(=O)n([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)s1,,CO,,O,C[O-].[Na+],test
US20100267780A1,N#Cc1ccc(Cl)c(-c2ccc(CNCCC3CCCCC3)cn2)c1.OO>>NC(=O)c1ccc(Cl)c(-c2ccc(CNCCC3CCCCC3)cn2)c1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US05015651,CCCc1ccc(C(=O)OCC)n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCc1ccc(C(=O)OCC)n1Cc1ccc(-c2ccccc2C(=O)O)cc1,,O,,O=CO,,test
US20120232225A1,C#CCBr.COC(=O)CCc1ccc(O)cc1>>C#CCOc1ccc(CCC(=O)O)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04537886,CCOC(=O)c1cn(-c2ccc(C)cc2)[nH]c1=O>>Cc1ccc(-n2cc(C(=O)O)c(=O)[nH]2)cc1,,[Na+],[OH-],CCO,,test
US20150087663A1,C[C@H](N)c1nc2cccc(F)c2c(=O)n1-c1ccccc1.Cc1noc(-c2c(N)ncnc2Cl)n1>>Cc1noc(-c2c(N)ncnc2N[C@@H](C)c2nc3cccc(F)c3c(=O)n2-c2ccccc2)n1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20030036651A1,CCOC(=O)CCCCc1ccco1.O=Cc1cccnc1Nc1cccc([N+](=O)[O-])c1>>O=c1c(CCCc2ccco2)cc2cccnc2n1-c1cccc([N+](=O)[O-])c1,,CN(C)C=O,,CC(C)[N-]C(C)C.[Li+],,test
US20040254077A1,CSC(Cl)C(N)=O.Cn1c(C(F)(F)F)cc(=O)n(-c2cc(O)c(Cl)cc2F)c1=O>>CSC(Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl)C(N)=O,,COCCOC,O,[H-].[Na+],,test
US04431589,Cn1nc(N)c(C#N)n1.O=[N+]([O-])c1cc(Cl)c(Cl)cc1Cl>>Cn1nc(C#N)c(Nc2cc(Cl)c(Cl)cc2[N+](=O)[O-])n1,,C1CCOC1,,[H-].[Na+],,test
US20140206681A1,CC1(C)OC(=O)N2C[C@H](c3ncc4c(Cl)nccn34)CC[C@H]21.O=C1CCC(=O)N1Br>>CC1(C)OC(=O)N2C[C@H](c3nc(Br)c4c(Cl)nccn34)CC[C@H]21,,CC#N,,,,test
US20140275181A1,O=S(Cl)Cl.OCc1cccnc1N1CC[C@@H](F)C1>>F[C@@H]1CCN(c2ncccc2CCl)C1,,ClCCl,,,,test
US20130079341A1,Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1NC(=O)c1cc2ncc(NCCN3CCOCC3)nc2s1.Cl>>Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1NC(=O)c1cc2ncc(NCCN3CCOCC3)nc2s1.Cl,,C1COCCO1,,,,test
US05166214,CCCCCCCNCCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1.CN=C=O>>CCCCCCCN(CCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)C(=O)NC,,CCCCCC,,,,test
US20120101127A1,C=C(C)C.N#Cc1ccc(N)cc1.O=Cc1ccccc1Br>>CC1(C)CC(c2ccccc2Br)Nc2ccc(C#N)cc21,,CC#N,CCOC(C)=O,O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3],,test
US20150152108A1,CC1CN(C(=O)OC(C)(C)C)CCN1Cc1ccccc1.O=C(O)C(F)(F)F>>CC1CNCCN1Cc1ccccc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20050009863A1,CN1Cc2c(Cl)cc(Cl)cc2C(c2cccc(NC(=O)NC(CO)CO)c2)C1.Cl>>CN1Cc2c(Cl)cc(Cl)cc2C(c2cccc(NC(=O)NC(CO)CO)c2)C1.Cl,,Cl,,,,test
US20100216846A1,CC[C@H](O)CNN.COc1cc(N=C(NC(=O)c2cc(C)nc(Cl)c2)SC)cc(C(F)(F)F)c1>>CC[C@H](O)Cn1nc(Nc2cc(OC)cc(C(F)(F)F)c2)nc1-c1cc(C)nc(Cl)c1,,CCO,,,,test
US20080085890A1,N#Cc1cc(O)ccc1I>>NCc1cc(O)ccc1I,,C1CCOC1,,B,,test
US20110300165A1,Cc1cc(C#N)ccc1I.NO>>Cc1cc(C(N)=NO)ccc1I,,CO,,Cl,O=C([O-])O.[Na+],test
US04242345,CC(=O)CCCCBr.CCCCn1c(=O)c2[nH]cnc2n(CCCC)c1=O>>CCCCn1c(=O)c2c(ncn2CCCCC(C)=O)n(CCCC)c1=O,,CCO,,[Na],,test
US20120095046A1,COC(=O)c1cnsc1-c1ccccc1>>O=C(O)c1cnsc1-c1ccccc1,,C1CCOC1,O,[Li+].[OH-],,test
US20100216844A1,NC(=O)C(O)C(Cc1ccccc1)NC(=O)c1cccnc1-c1ncc(-c2ccccc2)[nH]1>>NC(=O)C(=O)C(Cc1ccccc1)NC(=O)c1cccnc1-c1ncc(-c2ccccc2)[nH]1,,CS(C)=O,,,,test
US20040157804A1,CCOP(=O)(CNC(=O)c1c2c(c(OC(c3ccccc3)c3ccccc3)c3ncccc13)C(=O)N(Cc1ccc(F)cc1)C2)OCC>>CCOP(=O)(CNC(=O)c1c2c(c(O)c3ncccc13)C(=O)N(Cc1ccc(F)cc1)C2)OCC,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120053209A1,CCNc1nc(CCCCNC(=O)/C=C/c2ccc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nc2)ccc1C(=O)NC>>CCNc1nc(CCCCNC(=O)/C=C/c2ccc(N)nc2)ccc1C(=O)NC,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080153852A1,Brc1ccoc1.O=Cc1ccccc1B(O)O>>O=Cc1ccccc1-c1ccoc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20060257987A1,BrCC1CCCCC1.COc1ccc(C(F)(F)F)cc1>>COc1ccc(C(F)(F)F)cc1CC1CCCCC1,,C1CCOC1,,CN(C)CCN(C)C,[Li]CCCC,test
US20090324581A1,COC(=O)c1ccc(CC(C)C)cc1C(F)(F)F>>CC(C)Cc1ccc(CO)c(C(F)(F)F)c1,,C1CCOC1,,Cl,[BH4-].[Li+],test
US05811540,CN(C)C=O.COc1ccnc(Cl)c1.OC[C@@H]1CCC(Sc2ccccc2)O1>>COc1ccnc(OC[C@@H]2CCC(Sc3ccccc3)O2)n1,,CCOCC,,O,,test
US20060040968A1,Clc1ccnc(Cl)n1.NCCc1ccc(O)cc1>>Oc1ccc(CCNc2nccc(Cl)n2)cc1,,CN(C)C=O,,,,test
US20070244092A1,CC(C)(C)c1nc2cc(S(=O)(=O)Cl)ccc2n1CC1CCOCC1.COC(=O)C1CCNCC1>>COC(=O)C1CCN(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCOCC2)CC1,CN(C)c1ccncc1,CC#N,,,,test
US05374729,CC1(C)CC(O)CC(C)(C)N1O.CS(C)=O>>CON1C(C)(C)CC(O)CC1(C)C,,CCCCCCC,CCOC(C)=O,OO,,test
US05576324,Cc1cc2c(c3c1NC(=O)CC3)OC(C(N)=O)C2>>Cc1cc2c(c3c1NC(=O)CC3)OC(C#N)C2,,ClCCl,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,c1ccncc1,test
US20090192138A1,CC(C)(C)OC(=O)N[C@H]1CCCNC1.COc1cccc(C(=O)Cn2cnc3c(C#N)c(Cl)n(-c4ccccc4)c3c2=O)c1>>COc1cccc(C(=O)Cn2cnc3c(C#N)c(N4CCC[C@H](N)C4)n(-c4ccccc4)c3c2=O)c1,,CC(=O)N(C)C,,,,test
US05104892,CN.CS(=O)(=O)Nc1ccc(SCCCI)cc1>>CNCCCSc1ccc(NS(C)(=O)=O)cc1.I,,O,,C1CCOC1,,test
US06403561B1,CCCCNC(=O)C1Nc2ccccc2C1(C)C.CC[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CCCCNC(=O)C1N(C(=O)[C@H](CC)NC(=O)OCc2ccccc2)c2ccccc2C1(C)C,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,O=C1OCCN1P(=O)(Cl)N1CCOC1=O,test
US20100093730A1,O=C1CN(C(c2ccccc2)c2ccccc2)CCN1.O=C1N(CCBr)CCC1(c1ccccc1)c1ccccc1>>O=C1CN(C(c2ccccc2)c2ccccc2)CCN1CCN1CCC(c2ccccc2)(c2ccccc2)C1=O,,CN(C)C=O,,[H-].[Na+],,test
US20090264431A1,CC(C)(C)OC(=O)N1C[C@H](N)C[C@@H]1COC(=O)C(C)(C)C.O=S(=O)(Cl)c1cc(Cl)ccc1Cl>>CC(C)(C)OC(=O)N1C[C@H](NS(=O)(=O)c2cc(Cl)ccc2Cl)C[C@@H]1COC(=O)C(C)(C)C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20030186970A1,CC(C)Oc1cc(C(F)(F)F)c2cc3c(cc2n1)OCC(CO)N3CC(F)(F)F.CCCI>>CCCOCC1COc2cc3nc(OC(C)C)cc(C(F)(F)F)c3cc2N1CC(F)(F)F,,C1CCOC1,,[H-].[Na+],,test
US20090286778A1,Clc1nc2ccccc2s1.O=C(CC1CCNCC1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F>>O=C(CC1CCN(c2nc3ccccc3s2)CC1)Nc1ccc2cc1CCc1cncc(c1)Nc1ncc(Cl)c(n1)N2.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,,CO,,,,test
US20120149681A1,CC(C)(C)OC(=O)N1CCC(O)CC1.CN(C)Cc1cc(Cl)nc(Cl)c1>>CN(C)Cc1cc(Cl)nc(OC2CCN(C(=O)OC(C)(C)C)CC2)c1,,CN(C)C=O,CO,[H-].[Na+],,test
US05190959,ClC(c1ccccc1)c1cccs1.O=[N+]([O-])c1ccccc1OC/C=C/CN1CCC(O)CC1>>O=[N+]([O-])c1ccccc1OC/C=C/CN1CCC(OC(c2ccccc2)c2cccs2)CC1,,CC(=O)CC(C)C,,CCN(C(C)C)C(C)C,,test
US20150025070A1,COC(=O)C1CCN(CC(=O)OC(C)(C)C)CC1>>COC(=O)C1CCN(CC(=O)O)CC1,,C1COCCO1,ClCCl,Cl,,test
US20070032478A1,CN1CCN(c2ccc(N)cc2)CC1.Cc1cc(C(=O)Nc2cccc(Cc3ccc4c(c3)NC(=O)C4=CO)c2)n(C)n1>>Cc1cc(C(=O)Nc2cccc(Cc3ccc4c(c3)NC(=O)C4=CNc3ccc(N4CCN(C)CC4)cc3)c2)n(C)n1,,C1CCOC1,,,,test
US20120142717A1,Clc1ccc(Cl)nn1.OCCc1ccc(O)cc1>>OCCc1ccc(Oc2ccc(Cl)nn2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090143371A1,Cc1onc(-c2ccccc2)c1CO.N#Cc1ccc(Cl)nc1>>Cc1onc(-c2ccccc2)c1COc1ccc(C#N)cn1,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20050222261A1,CC(C)(C)OC(=O)COc1ccc(CCO)cc1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)COc1ccc(CCOS(C)(=O)=O)cc1,,ClCCl,,CCN(CC)CC,,test
US20120196869A1,COC(=O)c1ccc(OCC(C)(C)O)c(OC)c1.COCCN(CCOC)S(F)(F)F>>COC(=O)c1ccc(OCC(C)(C)F)c(OC)c1,,ClCCl,,,,test
US20030087926A1,C=Cc1cccc(Br)c1.CCC(=O)C(=O)[O-].Nc1cc(Cl)cc(Cl)c1>>O=C(O)C1CC(c2cccc(Br)c2)c2c(Cl)cc(Cl)cc2N1,,CC#N,CCO,O=C(O)C(F)(F)F,[Na+].[OH-],test
US04144341,C=CCn1c(=O)n(-c2ccc3c(c2)OCO3)c2nc(N)ccc21.CCOC(=O)Cl>>C=CCn1c(=O)n(-c2ccc3c(c2)OCO3)c2nc(C(=O)OCC)ccc21,,c1ccncc1,,,,test
US20020087002A1,C=O.COc1ccc(F)c(F)c1.Cl>>COc1cc(F)c(F)cc1CCl,,CC(=O)O,CCOCC,O=C([O-])O.[Na+],,test
US20150291533A1,COC(=O)C1=Cc2ccccc2N(C(=O)OC(C)(C)C)C[C@H]1C>>COC(=O)C1Cc2ccccc2N(C(=O)OC(C)(C)C)C[C@H]1C,[Pd],CCO,,[H][H],,test
US06140318,[N-]=[N+]=NCCc1cccc([N+](=O)[O-])c1>>NCCc1cccc([N+](=O)[O-])c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140296205A1,CN(C(=O)OC(C)(C)C)C1=N[C@H]2[C@H](O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](O)[C@@H]2F)S1>>CN(C(=O)OC(C)(C)C)C1=N[C@H]2[C@H](O[C@H](CO[Si](C)(C)C(C)(C)C)C(=O)[C@@H]2F)S1,,CCOCC,ClCCl,,,test
US20110166123A1,CC(C)[C@H](N)CO.CCOC(=O)C(=CN(C)C)C(=O)c1cc(OCc2ccc(F)cc2)ccc1Br>>CCOC(=O)C(=CN[C@H](CO)C(C)C)C(=O)c1cc(OCc2ccc(F)cc2)ccc1Br,,C1CCOC1,CCOC(C)=O,,,test
US04999356,Fc1ccc(-n2nc(N3CCNCC3)c3ccccc32)cc1.NC(=O)N[N+](=O)[O-]>>NC(=O)N1CCN(c2nn(-c3ccc(F)cc3)c3ccccc23)CC1,,O,,CN(C)C=O,,test
US20150011532A1,CC#N.CCOC(=O)c1cnc(Nc2ccc3ncsc3c2)cc1NC(C)C>>CC(C)Nc1cc(Nc2ccc3ncsc3c2)ncc1-c1cnco1,,O,,CO,O=C(O)C(F)(F)F,test
US20040106653A1,CCOC(=O)c1ccc(S(=O)(=O)c2ccc(C[C@@H](C)N)cc2)cc1.c1ccc([C@@H]2CO2)cc1>>CCOC(=O)c1ccc(S(=O)(=O)c2ccc(C[C@@H](C)NC[C@H](O)c3ccccc3)cc2)cc1,,CCO,ClC(Cl)Cl,,,test
US20090281088A1,C1CNCCNC1.Clc1ncc(Br)cn1>>Brc1cnc(N2CCCNCC2)nc1,,CC#N,,,,test
US20090306041A1,CN(C)c1ccc2c(c1)CCNC2=O.Cc1c(Br)cccc1Br>>Cc1c(Br)cccc1N1CCc2cc(N(C)C)ccc2C1=O,,ClCCl,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US05831072,Cl.[N-]=[N+]=CC(=O)c1ncn([C@@H]2O[C@H](COC(=O)c3ccccc3)[C@@H](OC(=O)c3ccccc3)[C@@H]2F)c1N1C(=O)c2ccccc2C1=O>>O=C(OC[C@H]1O[C@@H](n2cnc(C(=O)CCl)c2N2C(=O)c3ccccc3C2=O)[C@@H](F)[C@@H]1OC(=O)c1ccccc1)c1ccccc1,,ClCCl,,CCOCC,,test
US20120302566A1,CI.COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(O)cc5C)cccc43)ccc21>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(OC)cc5C)cccc43)ccc21,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130045964A1,CC(C)(O)CN.O=C(O)CCNC(=O)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1>>CC(C)(O)CNC(=O)CCNC(=O)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150376160A1,CCOC(=O)C1(c2ccc(-c3ccc(-c4sc(Cl)cc4NC(=O)O[C@H](C)c4ccccc4)cc3OC)cc2)CC1>>COc1cc(-c2sc(Cl)cc2NC(=O)O[C@H](C)c2ccccc2)ccc1-c1ccc(C2(C(=O)O)CC2)cc1,,CC(C)O,,Cl,[Na+].[OH-],test
US20160039815A1,COC(=O)CCC(=O)O.Nc1cnc(Cl)cc1C(=O)O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COC(=O)CCNC(=O)Nc1cnc(Cl)cc1C(=O)O,,Cc1ccccc1,,CCOC(C)=O,,test
US20120029190A1,Brc1ccccn1.N#Cc1cccc(C(=O)O)c1.N#Cc1cccc(N2Cc3nc(-c4ccccn4)oc3C2)c1>>N#Cc1cccc(-c2nc3c(o2)CN(c2ccccn2)C3)c1,,CO,,ClCCl,,test
US20160009740A1,C=CCBr.CCCCCC(O)C=CB1OC(C)(C)C(C)(C)O1>>C=CCOC(/C=C/B1OC(C)(C)C(C)(C)O1)CCCCC,,C1CCOC1,,[H-].[Na+],,test
US20110105462A1,Cc1ccc(S(=O)(=O)OCC2COc3ccc(OS(=O)(=O)C(F)(F)F)cc3O2)cc1.NCCO>>O=S(=O)(Oc1ccc2c(c1)OC(CNCCO)CO2)C(F)(F)F,,CC#N,,,,test
US20050250810A1,CNC(=O)c1nn(C)c2ccccc12>>CNCc1nn(C)c2ccccc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140206673A1,CC1(C)Cc2c(C#N)c(O)nc(C3CC3)c2CO1.O=P(Cl)(Cl)Cl>>CC1(C)Cc2c(C#N)c(Cl)nc(C3CC3)c2CO1,CN(C)C=O,,,,,test
US20080300242A1,COc1cc(N2CCC(CN3CCCCC3)CC2)ccc1N.O=C(Nc1c(F)cccc1F)c1cccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)c1>>COc1cc(N2CCC(CN3CCCCC3)CC2)ccc1Nc1nccc(-c2c(-c3cccc(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1,,OCC(F)(F)F,,Cl,,test
US20090239845A1,Cc1cc(C(=O)NCc2ccccn2)nn1Cc1cc(Cl)ccc1O.Fc1ccccc1CBr>>Cc1cc(C(=O)NCc2ccccn2)nn1Cc1cc(Cl)ccc1OCc1ccccc1F,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080280875A1,CCOC(=O)c1cc(Oc2ccc(C(F)F)cc2)c2cc(C)oc2c1.O=C1CCC(=O)N1Br>>CCOC(=O)c1cc(Oc2ccc(C(F)F)cc2)c2cc(CBr)oc2c1,,ClC(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20110118230A1,Brc1ccc(Br)cc1.Fc1ccccn1>>Brc1ccc(-c2ccccn2)cc1,,CCOCC,,[Li]CCCC,,test
US20110319394A1,CCn1c(=O)n(-c2ccc(O)cc2)c2ncc(C)cc21.Cn1c(S(C)(=O)=O)nc2cccnc21>>CCn1c(=O)n(-c2ccc(Oc3nc4cccnc4n3C)cc2)c2ncc(C)cc21,,CN(C)C=O,,[H-].[Na+],,test
US05536701,CN.Cn1nc(C(F)(F)F)cc1Oc1cnnc(Oc2cc(C(F)(F)F)nn2C)c1>>CNc1cnnc(Oc2cc(C(F)(F)F)nn2C)c1,,C1CCOC1,,,,test
US20070043040A1,O=S(=O)(NCCNCCSc1ccc(Br)cc1)c1cccc2cnccc12.O=S([O-])OO>>O=S(=O)(CCNCCNS(=O)(=O)c1cccc2cnccc12)c1ccc(Br)cc1,,CO,,O,,test
US05117057,Cc1ccccc1[PH](=O)NNC(C)(C)C.O=C(Cl)c1ccccc1>>CN(N(C(=O)c1ccccc1)C(C)(C)C)[PH](=O)c1ccccc1,,CCCCCC,CCOCC,CCN(CC)CC,,test
US20080090804A1,Fc1cc2c(cc1Br)N=Cc1ccccc1O2.O=C1CCCC(=O)O1>>O=C(O)[C@@H]1CCC(=O)N2c3cc(Br)c(F)cc3Oc3ccccc3[C@@H]12,,Cc1ccccc1C,,CCOCC,,test
US20030195353A1,C=CCO.CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H]1CC=CC(=O)O1>>CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1,,Cc1ccccc1,,Cl,[Li+].[OH-],test
US20110118230A1,Cn1cc(-c2cnc3c(c2)c2c(SC4CCN(C(=O)OC(C)(C)C)CC4)c(C#N)ncc2n3COCC[Si](C)(C)C)cn1>>Cn1cc(-c2cnc3[nH]c4cnc(C#N)c(SC5CCNCC5)c4c3c2)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04233309,CC(=O)O.Cc1ccc(C)n1C(C)C(C)O>>CC(=O)CCC(C)=O.CC(N)C(C)O,,CC(=O)O,ClCCl,CS(C)=O,O=C(Cl)C(=O)Cl,test
US20080064871A1,O=C(Cl)c1ccc(O)c(Cl)c1.c1ccc2c(c1)NCCO2>>O=C(c1ccc(O)c(Cl)c1)N1CCOc2ccccc21,,CCOC(C)=O,COCCOC,CCO,,test
US20160009720A1,Cc1ccc(-c2c(-c3ccc(C#N)cc3)nc(C=O)c3nccn23)cc1>>Cc1ccc(-c2c(-c3ccc(C#N)cc3)nc(CO)c3nccn23)cc1,,CO,ClCCl,[BH4-].[Na+],,test
US20080108651A1,CCOC(CCNc1cc(OC(=O)c2ccccc2)c2sccc2n1)OCC.Cl>>Cl.O=CCCNc1cc(OC(=O)c2ccccc2)c2sccc2n1,,C1CCOC1,,,,test
US20090291977A1,COC(=O)c1cc(NC2CCOc3cccc(C)c32)c2nc(C)c(C)n2c1>>Cc1cccc2c1C(Nc1cc(C(=O)O)cn3c(C)c(C)nc13)CCO2,,CO,,C1CCOC1,[Na+].[OH-],test
US20120177681A1,CCOC(=O)N(Cc1ccc(CP(=O)(OCC)OCC)cc1)c1cc(Br)nc(N)c1[N+](=O)[O-].COCCO>>CCOC(=O)N(Cc1ccc(CP(=O)(OCC)OCC)cc1)c1cc(OCCOC)nc(N)c1[N+](=O)[O-],,C1CCOC1,,[H-].[Na+],,test
US20050113397A1,CCOC(=O)C(C(C)=O)C1C=CCCC1.N#CCc1nc2ccccc2[nH]1>>Cc1c(C2C=CCCC2)c(=O)n2c([nH]c3ccccc32)c1C#N,,O,,C,O=C[O-].[NH4+],test
US20140275020A1,Cc1c([C@@H](O)CN2CCCC2CNC(=O)OC(C)(C)C)ccc2c1COC2=O.Cl>>Cc1c([C@@H](O)CN2CCCC2CN)ccc2c1COC2=O.Cl,,C1COCCO1,,,,test
US20150291549A1,Cc1c(COc2cc(OCc3cncc(C#N)c3)c(C=O)cc2Cl)cccc1-c1ccc2c(c1)OCCO2.NC(=O)C[C@H](N)C(=O)O>>Cc1c(COc2cc(OCc3cncc(C#N)c3)c(CN[C@@H](CC(N)=O)C(=O)O)cc2Cl)cccc1-c1ccc2c(c1)OCCO2,,CN(C)C=O,,CC(=O)O,[BH3-]C#N.[Na+],test
US20060276465A1,CC1(C)C=C(c2ccccc2O)CC(C)(C)C1>>CC1(C)CC(c2ccccc2O)CC(C)(C)C1,[Pd],CO,,,,test
US20070197512A1,C=CC(=O)OC.CC(C)c1cccc2c1OC(C(C)C)C(=O)N2>>COC(=O)CCN1C(=O)C(C(C)C)Oc2c(C(C)C)cccc21,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US04945186,BrBr.O=Cc1ccccc1>>O=Cc1cccc(Br)c1,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100273770A1,NC(=O)CCc1cccc(OCc2ccccc2)c1>>NCCCc1cccc(OCc2ccccc2)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080262028A1,CCOC(C)=O.CS(=O)(=O)OCc1cc(-c2ccc(Cl)s2)on1.Nc1ccc(CC(C(=O)O)c2c[nH]cn2)cn1>>CCOC(=O)[C@@H](Cc1ccc(N)nc1)c1cn(Cc2cc(-c3ccc(Cl)s3)on2)cn1,,CN(C)C=O,,[H-].[Na+],,test
US20100197675A1,NCC12CC3CC(CC(C3)C1)C2.c1ccc(COc2ccc(C3CO3)cc2)cc1>>OC(CNCC12CC3CC(CC(C3)C1)C2)c1ccc(OCc2ccccc2)cc1,,CC(C)O,,,,test
US20090192203A1,NC(=S)CCCO.O=C(CBr)c1ccc(C(F)(F)F)cc1>>OCCCc1nc(-c2ccc(C(F)(F)F)cc2)cs1,,CCO,,,,test
US05670505,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)N1CCN(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](Cc2ccccc2)C1.Cl>>Cl.O=C([C@@H]1C[C@@H](O)CN1)N1CCN(C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](Cc2ccccc2)C1,,C1COCCO1,ClCCl,,,test
US20150291514A1,COc1cccc(O)c1.N#Cc1ccc(F)cc1>>COc1cccc(Oc2ccc(C#N)cc2)c1,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20060030595A1,N#Cc1cccc(C(O)c2cccc(Br)n2)c1.O=S(Cl)Cl>>N#Cc1cccc(C(Cl)c2cccc(Br)n2)c1,,ClCCl,,,,test
US20030181726A1,CC(CC(c1ccc(O)cc1)c1ccc(O)cc1)NCc1ccccc1.CS(=O)(=O)Nc1cc(OC[C@@H]2CO2)ccc1OCc1ccccc1>>CC(CC(c1ccc(O)cc1)c1ccc(O)cc1)N(Cc1ccccc1)C[C@H](O)COc1ccc(OCc2ccccc2)c(NS(C)(=O)=O)c1,,CO,,O=C([O-])O.[Na+],,test
US20080318922A1,CCOC(=O)c1c(N)c(C#N)c(N2CCC[C@@H](NC(=O)OC(C)(C)C)C2)n1Cc1cc(F)ccc1Cl.COC(=O)C#N>>COC(=O)c1nc2c(C#N)c(N3CCC[C@@H](N)C3)n(Cc3cc(F)ccc3Cl)c2c(=O)[nH]1,,CO,Cl,,,test
US20090220514A1,COC(=O)[C@H](CCCc1ccccc1)[C@@H](C)O>>C[C@@H](O)[C@@H](CCCc1ccccc1)C(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20130336921A1,CN(CCN1CCOCC1)C(=O)c1cccc(C(=O)Cl)c1.Nc1ccc(N2CCCCC2)cc1C(=O)Nc1nc(-c2cccc(C(F)(F)F)c2)cs1>>CN(CCN1CCOCC1)C(=O)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2C(=O)Nc2nc(-c3cccc(C(F)(F)F)c3)cs2)c1,,CCOC(C)=O,ClCCl,c1ccncc1,,test
US20060166964A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccncc1Br>>CC(C)(C)OC(=O)Nc1ccncc1Br,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090270436A1,CC(C)(C)OC(=O)N1CCC2(CC1)CC(O[Si](C)(C)C(C)(C)C)c1cc(C#N)ccc1O2.NO>>CC(C)(C)OC(=O)N1CCC2(CC1)CC(O[Si](C)(C)C(C)(C)C)c1cc(C(N)=NO)ccc1O2,,CCO,,CCN(CC)CC,Cl,test
US20040204406A1,C#CCBr.COCCOCCO>>C#CCOCCOCCOC,,C1CCOC1,,O,,test
US20150307532A1,CCOP(=O)(CN)OCC.Clc1ncnc2sc(Br)cc12>>CCOP(=O)(CNc1ncnc2sc(Br)cc12)OCC,,C1COCCO1,CCOC(C)=O,CCN(CC)CC,,test
US05025025,COC(=O)CCCCC(CCN)Cc1cccnc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>COC(=O)CCCCC(CCNS(=O)(=O)c1ccc(Cl)cc1)Cc1cccnc1,,ClCCl,,CCN(CC)CC,,test
US05284841,ClCOc1ccc(Cl)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>Clc1ccc(OC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.[Cl-],,Cc1ccccc1,,,,test
US20080300288A1,Cc1cc(I)cc(C(=O)NO)c1O>>Cc1cc(I)cc2c(=O)[nH]oc12,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20130059834A1,CNC(=O)Cn1nc(-c2cnc3c(n2)c(C(=O)NC(C)(C)C)cn3COCC[Si](C)(C)C)c2cc(OC(F)F)ccc21>>CNC(=O)Cn1nc(-c2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)c2cc(OC(F)F)ccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140343092A1,COC(=O)CN(C)C(=O)c1c(C(=O)OC)c2ccccc2n1Cc1ccc(F)cc1>>COC(=O)c1c(O)c2c3ccccc3n(Cc3ccc(F)cc3)c2c(=O)n1C,,CN(C)C=O,,[H-].[Na+],,test
US05770180,C=C(C=C(OC)O[Si](C)(C)C)O[Si](C)(C)C.COC1CCC(OC)O1>>COC(=O)C1C(=O)CC2CCC1O2,Cl[Ti](Cl)(Cl)Cl,ClCCl,,O=C([O-])O.[Na+],,test
US20100068301A1,CCOC(=O)C(C)(C)Cc1c(SC(C)(C)C)c2cc(OCc3ccccn3)ccc2n1Cc1ccc(-c2ccc(OC)nc2)cc1>>COc1ccc(-c2ccc(Cn3c(CC(C)(C)C(=O)O)c(SC(C)(C)C)c4cc(OCc5ccccn5)ccc43)cc2)cn1,,C1CCOC1,,CO,[Li+].[OH-],test
US20020183353A1,C=C(Cl)CCl.OC[C@H]1COc2ccc(O)cc2O1>>C=C(Cl)COc1ccc2c(c1)OC(CO)CO2,,CN(C)C=O,,[H-].[Na+],,test
US20100093703A1,CC(C)(C)OC(=O)CN(c1ccc2[nH]ccc2c1)S(=O)(=O)c1cc(Cl)cc(Cl)c1.Clc1cc(Cl)nc(Cl)n1>>CC(C)(C)OC(=O)CN(c1ccc2c(ccn2-c2cc(Cl)nc(Cl)n2)c1)S(=O)(=O)c1cc(Cl)cc(Cl)c1,,CCOC(C)=O,,,,test
US05153210,CC(=O)Cc1ccc(OCCCCCCCCCCBr)cc1.O=C1CCNN1>>CC(=O)Cc1ccc(OCCCCCCCCCCN2CCC(=O)N2)cc1,,CC#N,O,Cl,[I-].[K+],test
US20090082367A1,CC(C)(C)OC(=O)NC1(c2nnc(C3CC3)n2C2CC2)CCC1>>NC1(c2nnc(C3CC3)n2C2CC2)CCC1,,CCO,,CCOC(C)=O,Cl,test
US04381395,Cc1[nH]cnc1CSCCN=C=S.N#CN>>Cc1[nH]cnc1CSCCNC(=S)NC#N,,ClC(Cl)Cl,,C1CCC2=NCCCN2CC1,,test
US05491144,COc1ccc(Nc2cc3c(cc2Nc2ccccc2)C(=O)NC3=O)cc1OC>>O=C1NC(=O)c2cc(Nc3ccc(O)c(O)c3)c(Nc3ccccc3)cc21,,ClCCl,,BrB(Br)Br,,test
US20080177095A1,COCOc1cc2c(c(F)c1F)OCCC2.II>>COCOc1c(F)c(F)c2c(c1I)CCCO2,,C1CCOC1,COC(C)(C)C,[Li]CCCC,,test
US20090247578A1,BrCc1ccccc1.O=C(O)c1cn(C2CC2)c2cc(N3CCC(COc4ccc(N5C[C@H](CO)OC5=O)cc4F)CC3)c(F)cc2c1=O>>O=C(OCc1ccccc1)c1cn(C2CC2)c2cc(N3CCC(COc4ccc(N5C[C@H](CO)OC5=O)cc4F)CC3)c(F)cc2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06008230,O=C(Nc1cccc2c(N=P(c3ccccc3)(c3ccccc3)c3ccccc3)ccnc12)c1c(Cl)cccc1Cl>>Nc1ccnc2c(NC(=O)c3c(Cl)cccc3Cl)cccc12,,CC(=O)O,,Cl,[Na+].[OH-],test
US06515011B2,N#Cc1cc(Cl)ccc1CBr.OC1CNC1>>N#Cc1cc(Cl)ccc1CN1CC(O)C1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20100016315A1,COc1ccc(S(C)(=O)=O)cc1CBr.NC(=O)c1cc(Cl)cnc1N>>Br.COc1ccc(S(C)(=O)=O)cc1Cn1cc(Cl)cc(C(N)=O)c1=N,,CCOC(C)=O,CN(C)C=O,,,test
US20090253687A1,NNc1ccccc1.O=C1COc2ccc(C(=O)C=C(O)C(F)(F)F)cc2N1>>O=C1COc2ccc(-c3cc(C(F)(F)F)nn3-c3ccccc3)cc2N1,,CCO,,,,test
US20050070583A1,CCc1cc(SCC=C(c2ccc(Br)cc2)c2ccc(Br)cc2)ccc1OCC(=O)OC>>CCc1cc(SCC=C(c2ccc(Br)cc2)c2ccc(Br)cc2)ccc1OCC(=O)O,,CCO,,Cl,[Na+].[OH-],test
US20090286778A1,COC(=O)CBr.O=c1[nH]c2cc([N+](=O)[O-])cc(I)c2o1>>COC(=O)Cn1c(=O)oc2c(I)cc([N+](=O)[O-])cc21,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20050282824A1,COC(=O)[C@H](CSCc1ccccc1)NC(=O)c1cc(C)nc(N2CCC(c3ccccc3)CC2)n1>>Cc1cc(C(=O)N[C@@H](CSCc2ccccc2)C(=O)O)nc(N2CCC(c3ccccc3)CC2)n1,,C1CCOC1,,CO,[Li+].[OH-],test
US20150239838A1,O=C(O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(-c3ccccc3Cl)c2F)c2c1CCCC2.[NH4+]>>NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(-c3ccccc3Cl)c2F)c2c1CCCC2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150284409A1,C=CCO[C@@H](C)C[C@@H](C)C(N)C(=O)OCC.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=CCO[C@@H](C)C[C@@H](C)C(NC(=O)OC(C)(C)C)C(=O)OCC,,ClCCl,,CCN(CC)CC,,test
US20120135990A1,CC(C)(C)OC(=O)N1CC(Oc2ccc(F)c(F)c2)C2C1CCN2C(=O)C(NC(=O)OCc1ccccc1)C(C)(C)C>>CC(C)(C)OC(=O)N1CC(Oc2ccc(F)c(F)c2)C2C1CCN2C(=O)C(N)C(C)(C)C,,CCOC(C)=O,CO,,,test
US20080009530A1,CCOC(=O)CBr.COCOc1ccc(C=O)c(Oc2ncc(C(F)(F)F)cc2Cl)c1>>COCOc1ccc(CC=O)c(Oc2ncc(C(F)(F)F)cc2Cl)c1,,C1CCOC1,,CC(C)(C)O,CC(C)(C)[O-].[K+],test
US20070167433A1,COCCCN1CCOc2ccc(CO[C@H]3CN(C(=O)OCc4ccccc4)C[C@@H](OCCOS(=O)(=O)c4ccc(C)cc4)[C@@H]3c3ccc(COCCOC)cc3)cc21.c1nc[nH]n1>>COCCCN1CCOc2ccc(CO[C@H]3CN(C(=O)OCc4ccccc4)C[C@@H](OCCn4cncn4)[C@@H]3c3ccc(COCCOC)cc3)cc21,,CN(C)C=O,,[Na],,test
US04374836,COc1cccc(Cc2nnc(SC)[nH]c2=O)c1.N=C(N)Nc1nc(CSCCN)cs1>>COc1cccc(Cc2nnc(NCCSCc3csc(NC(=N)N)n3)[nH]c2=O)c1,,CN(C)C=O,,,,test
US20130079373A1,CC(C)(C)OC(=O)NS(=O)(=O)NCc1ccc(NC(=O)NCc2ccc(C(F)(F)F)nc2OC2CCCC2)cc1F>>NS(=O)(=O)NCc1ccc(NC(=O)NCc2ccc(C(F)(F)F)nc2OC2CCCC2)cc1F,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20140371199A1,CCOC(=O)c1ccc(-c2ccc3ncc(I)n3c2)cc1F.N#Cc1ccc(B(O)O)cc1>>CCOC(=O)c1ccc(-c2ccc3ncc(-c4ccc(C#N)cc4)n3c2)cc1F,,C1COCCO1,,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US04960776,CN(C)CCNC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1.Cl>>CN(C)CCNC(=O)N1CCN(c2ccc(N)cc2)CC1.Cl,[Pd],CO,,,,test
US20130095193A1,C#Cc1nc(Br)cnc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.CC(C)(C)OC(=O)NC(CF)c1ccc(C(Cl)=NO)cc1>>CC(C)(C)OC(=O)NC(CF)c1ccc(-c2cc(-c3nc(Br)cnc3N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)on2)cc1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20060270692A1,O=C(Cn1cc(Nc2ncnc3cc(OCc4ccccc4)ccc23)cn1)Nc1cccc(F)c1F>>O=C(Cn1cc(Nc2ncnc3cc(O)ccc23)cn1)Nc1cccc(F)c1F,,O=C(O)C(F)(F)F,,,,test
US08450332B2,C=CCC1(C(=O)Nc2cccc(Cl)c2)CCN(C(=O)OC(C)(C)C)CC1.C=CCC1(C(=O)O)CCN(C(=O)OC(C)(C)C)CC1.CN(C)C=O.Nc1cccc(Cl)c1.c1ccncc1>>C=CCC1(C(=O)Nc2cccc(Cl)c2)CCN(c2ncnc3[nH]cc(C)c23)CC1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20090093476A1,COC(=O)c1cc(Br)c[nH]1.O=[N+]([O-])c1ccccc1F>>COC(=O)c1c(Br)ccn1-c1ccccc1[N+](=O)[O-],,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20070161686A1,COc1cc(N2CCOCC2)ccc1-c1nnc(-c2c(-c3ccccc3)noc2Cl)o1.[C-]#N>>COc1cc(N2CCOCC2)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C#N)o1,,CN(C)C=O,,O,,test
US04430498,O=C(Cc1ccccc1)N[C@@H]1C(=O)N2C(C(=O)O)=CCS[C@H]12.[N-]=[N+]=C(c1ccccc1)c1ccccc1>>O=C(Cc1ccccc1)N[C@@H]1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=CCS[C@H]12,,C1COCCO1,CO,CC(=O)O,,test
US20160176868A1,CC(C)NC(N)=O.COC(=O)C(CCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)C(=O)OC>>CC(C)N1C(=O)NC(=O)C(CCCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C1=O,,CO,,C[O-].[Na+],,test
US20040242583A1,O=C1CC(=O)NC(=O)N1.O=P(Cl)(Cl)Cl>>O=c1cc[nH]c(=O)n1Cl,,O,,,,test
US04145430,C=CC1=CN2C(=O)C[C@H]2O1>>CC=C1CN2C(=O)C[C@H]2O1,[Pt],C1CCOC1,,[H][H],,test
US06251911B1,Nc1n[nH]c2ncnc(Nc3cccc(Cl)c3)c12.O=Cc1cccc(-c2nnn[nH]2)c1>>Clc1cccc(Nc2ncnc3[nH]nc(N=Cc4cccc(-c5nnn[nH]5)c4)c23)c1,,CO,,CC(=O)O,,test
US20150126751A1,CCCCCCCCCCCCCCBr.c1ccsc1>>CCCCCCCCCCCCCCc1cccs1,,C1CCOC1,,[Li]CCCC,,test
US20060287342A1,Cc1ccccc1.O=c1c(Br)c(Cl)n(Cc2ccccc2)c(=O)n1Cc1ccccc1.OB(O)c1ccc(Cl)cc1>>O=c1c(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)n(Cc2ccccc2)c(=O)n1Cc1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20080312208A1,Cc1nc(Cl)c(C#N)cc1C(=O)O.O=C(Cl)C(=O)Cl>>Cc1nc(Cl)c(C#N)cc1C(=O)Cl,,ClCCl,,,,test
US20080139631A1,CCCc1cc2c(C(F)(F)F)c(C#N)ccc2n1CC(=N)NO.O=C(Cl)c1cc(C(F)(F)F)cc(Cl)c1F>>CCCc1cc2c(C(F)(F)F)c(C#N)ccc2n1Cc1noc(-c2cc(C(F)(F)F)cc(Cl)c2F)n1,,CC#N,,CCN(C(C)C)C(C)C,,test
US06960586B2,O=Cc1c(O)ccc2cc(Br)ccc12.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>O=Cc1c(OS(=O)(=O)C(F)(F)F)ccc2cc(Br)ccc12,,ClCCl,,CCN(CC)CC,,test
US05081238,CC(O)C1C(=O)NC1C#C[Si](C)(C)C>>C#CC1NC(=O)C1C(C)O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04229461,CCOC(=O)C1SCCN1C(=S)Nc1cc(Cl)cc(Cl)c1>>O=C1C2SCCN2C(=S)N1c1cc(Cl)cc(Cl)c1,,Cl,,,,test
US20140155381A1,Cc1nc(C(O)CCC(C)C)c(C)o1>>Cc1nc(C(=O)CCC(C)C)c(C)o1,O=[Mn]=O,ClCCl,,,,test
US20150223461A1,OCc1cncc(Cl)c1>>O=Cc1cncc(Cl)c1,,CS(C)=O,,CCN(CC)CC,Cl,test
US05387603,CC(=O)N1CCc2cc(CC(C)Br)ccc21.O=[N+]([O-])O>>CC(=O)N1CCc2cc(CC(C)Br)cc([N+](=O)[O-])c21,,CC(=O)O,,,,test
US20060270652A1,CC(C)c1nc2c(C(=O)NCC3CCN(CC4CCNCC4)CC3)cccc2[nH]1.O=C(Cl)Oc1ccccc1>>CC(C)c1nc2c(C(=O)NCC3CCN(CC4CCN(C(=O)Oc5ccccc5)CC4)CC3)cccc2[nH]1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040014770A1,CC(=O)CCl.CC(C)(C)OC(=O)N1CCNCC1.ClCCl>>CC(C)C(=O)N1CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20040167174A1,CC(=O)OC(C)=O.CCOc1cc(C(CC(=O)NO)N2C(=O)c3ccc(NC(C)=O)cc3C2=O)ccc1OC>>CCOc1cc(C(CC(=O)NOC(C)=O)N2C(=O)c3ccc(NC(C)=O)cc3C2=O)ccc1OC,,CC#N,,,,test
US20160184318A1,O=C(O)CCCCCc1cn(Cc2ccccc2)nn1>>O=C(O)CCCCCc1c[nH]nn1,[Pd],O,,CC(=O)O,,test
US20070225269A1,CCOC(=O)/C=C1\CCCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CCC/C(=C\CO)C1,,Cc1ccccc1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20150239866A1,Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cn(C[C@H](O)CC#N)nn2)c1.OO>>Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cn(C[C@H](O)CC(N)=O)nn2)c1,,CC#N,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090264445A1,CCCc1ccccc1O/C(=C/C(=O)OCC)CBr.COC(=O)[C@@H](N)CC1CCCCC1>>CCCc1ccccc1OC1=CC(=O)N([C@@H](CC2CCCCC2)C(=O)OC)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04734338,CCCCCCCCCCCCCCCCCCCC(=O)O>>CCCCCCCCCCCCCCCCCC(=O)O,,ClC(Cl)Cl,,,,test
US20130245021A1,CC(=O)c1ccc(-c2cnc3ccc(F)nn23)s1.CN(CCCN)C(=O)OC(C)(C)C>>CC(=O)c1ccc(-c2cnc3ccc(NCCCN(C)C(=O)OC(C)(C)C)nn23)s1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090318474A1,Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)Cl)c3)n2)n1.NCCOCCO>>Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)NCCOCCO)c3)n2)n1,,C1CCOC1,CCOC(C)=O,,,test
US20090270363A1,COCCOCOC1CCCc2nc(-c3ccc(N(C)C)cc3CN3CCC3)sc21>>CN(C)c1ccc(-c2nc3c(s2)C(O)CCC3)c(CN2CCC2)c1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20050026914A1,COc1ccc([N+](=O)[O-])c(C=O)c1.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>COc1ccc([N+](=O)[O-])c(-c2cnco2)c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04590270,Cl.Nc1ncc(C2CCN(c3ccc([N+](=O)[O-])cc3)CC2)c(N)n1>>Nc1ncc(C2CCN(c3ccc(Cl)cc3)CC2)c(N)n1,[Fe],O,,,,test
US20110200549A1,CC(=O)NCCc1ccccc1.CCCCCI>>CCCCCN(CCc1ccccc1)C(C)=O,,C1CCOC1,,[H-].[Na+],,test
US20150342909A1,CCCCCCN.N#C[N-]C#N>>CCCCCCNC(=N)NC#N,,CCCCO,,Cl,,test
US06187769B1,BrCCCCBr.COc1ccc2c(c1)OC=CNC2=O>>COc1ccc2c(c1)OC=CN(CCCCBr)C2=O,,CN(C)C=O,,[H-].[Na+],,test
US20120252801A1,CC(C)=O.CC(C)c1ccc(NC(=O)CC2NCC(C)(C)OC2=O)cc1>>CC(C)c1ccc(NC(=O)CC2C(=O)OC(C)(C)CN2C(C)C)cc1,,C1CCOC1,CC#N,CC(=O)O,[BH3-]C#N.[Na+],test
US20110092505A1,CC(C)(C)OC(=O)N1CCN(c2cc(CN=[N+]=[N-])cc(-c3ccnc(NC4CCCCC4)c3)n2)CC1>>CC(C)(C)OC(=O)N1CCN(c2cc(CN)cc(-c3ccnc(NC4CCCCC4)c3)n2)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120157438A1,O=C(OCc1ccccc1)N1CCC(n2cnc3c(cc(Cc4ccc(Cl)nc4)c4ccccc43)c2=O)CC1>>O=c1c2cc(Cc3ccc(Cl)nc3)c3ccccc3c2ncn1C1CCNCC1,,Br,CC(=O)O,,,test
US20080171772A1,CCOC(=O)c1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3ccccn3)c2c1>>CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(C(=O)O)cc2n1Cc1ccccn1,,CCO,,O,[Na+].[OH-],test
US20140213586A1,COc1cc(N)cc(CO)c1.O=Cc1cccnc1>>COc1cc(CO)cc(N=Cc2cccnc2)c1,,CCO,,,,test
US20160145269A1,CCOC(=O)c1cn(CC(OC)OC)c(C(=O)OC)c(OCc2ccccc2)c1=O>>CCOC(=O)c1cn(CC=O)c(C(=O)OC)c(OCc2ccccc2)c1=O,,O=CO,,O=S(=O)(O)O,,test
US20140135359A1,C=C/C=C/C=C/c1c(O)ccc2c1OCCC2=O.CN(C)C(=S)Cl>>C=C/C=C/C=C/c1c(S)ccc2c1OCCC2=O,,C1COCCO1,,CCN(CC)CC,CN(C)c1ccccn1,test
US20070004725A1,Cc1ccc(S(=O)(=O)NC(Cc2ccc(Oc3ccc(CCC(=O)NOCc4ccccc4)cc3)cc2)C(=O)N(C)C)cc1>>Cc1ccc(S(=O)(=O)NC(Cc2ccc(Oc3ccc(CCC(=O)NO)cc3)cc2)C(=O)N(C)C)cc1,[Pd],CO,,[H][H],,test
US20080051404A1,CC(C)(C)[Si](C)(C)O[C@H]1C[C@@H](O)C[C@H]1COCc1ccccc1.CS(=O)(=O)Cl>>CC(C)(C)[Si](C)(C)O[C@H]1C[C@@H](OS(C)(=O)=O)C[C@H]1COCc1ccccc1,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20160194304A1,Cc1c(C(=O)N(C)c2ccc(OCc3ccccc3)cc2)cc(-c2cc3c(cc2C(=O)N2Cc4ccccc4C[C@H]2CN2CCOCC2)CN(C(=O)Cl)CC3)n1C.O=C(OCc1ccccc1)c1cccc(O)c1>>Cc1c(C(=O)N(C)c2ccc(OCc3ccccc3)cc2)cc(-c2cc3c(cc2C(=O)N2Cc4ccccc4C[C@H]2CN2CCOCC2)CN(C(=O)Oc2cccc(C(=O)OCc4ccccc4)c2)CC3)n1C,CN(C)c1ccncc1,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20160244434A1,Nc1cccc(Nc2ccc3ccccc3c2[N+](=O)[O-])c1.O=C(O)CCc1ccccn1>>O=C(CCc1ccccn1)Nc1cccc(Nc2ccc3ccccc3c2[N+](=O)[O-])c1,,CC#N,,CCN=C=NCCCN(C)C,Cl,test
US20030092712A1,O=c1ccc2c(-c3ccc(F)cc3Cl)nc(C3=CC4CCC(C3)N4)cc2n1-c1c(Cl)cccc1Cl>>O=c1ccc2c(-c3ccc(F)cc3Cl)nc(C3CC4CCC(C3)N4)cc2n1-c1c(Cl)cccc1Cl,O=[Pt]=O,CCOC(C)=O,,,,test
US09206126B2,CC1(C)OB(c2ccc(CCC#N)nc2)OC1(C)C.O=C(N[C@H](CF)[C@H](O)c1ccc(I)cc1)C(Cl)Cl>>N#CCCc1ccc(-c2ccc([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)cc2)cn1,,CN(C)C=O,,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],test
US20050148627A1,CCOC(=O)C1=Cc2cc(Cl)c(F)cc2OC1C(F)(F)F.Oc1ccc(Br)cc1Cl>>CCOC(=O)C1=Cc2cc(Cl)c(Oc3ccc(Br)cc3Cl)cc2OC1C(F)(F)F,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20120245144A1,CC(C)n1ncnc1-c1cn2c(n1)-c1cnc(Cl)cc1OCC2.CN1CCC(C2CCCN2)CC1>>CC(C)n1ncnc1-c1cn2c(n1)-c1cnc(N3CCCC3C3CCN(C)CC3)cc1OCC2,,CN1CCCC1=O,,,,test
US20080262050A1,CCC1=Cc2ccc(OC)cc2CC1>>CCC1CCc2cc(OC)ccc2C1,[Pd],CO,,,,test
US04564386,CC(C)(C)N.O=S(=O)(Cl)c1ccc(NS(=O)(=O)C(F)(F)F)c(Cl)c1>>CC(C)(C)NS(=O)(=O)c1ccc(NS(=O)(=O)C(F)(F)F)c(Cl)c1,,C1CCOC1,,,,test
US20100087418A1,CC(C)(C)OC(=O)N1CCOc2c(cccc2-c2cccc(F)c2)C1.Cl>>Cl.Fc1cccc(-c2cccc3c2OCCNC3)c1,,CCOC(C)=O,,,,test
US20070213348A1,COC(=O)c1ccc(C(=C2CC(C)(C)CC(C)(C)C2)c2ccc(O)cc2)cc1.Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1.OB(O)c1ccoc1>>Oc1ccc(C(=C2CCCCCCC2)c2ccc(-c3ccoc3)cc2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20050239767A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCC1Cn2c(nc3ccccc32)-c2ccccc2O1>>Cc1ccc(S(=O)(=O)OCC2Cn3c(nc4ccccc43)-c3ccccc3O2)cc1,,c1ccncc1,,,,test
US05747517,O=C1CSC(=S)N1.O=Cc1cccc(OCc2ccc(C(=O)c3ccccc3)cc2)c1>>O=C1NC(=S)SC1=Cc1cccc(OCc2ccc(C(=O)c3ccccc3)cc2)c1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US05453533,COC(=O)c1ccc(NC(C)=O)c([N+](=O)[O-])c1.Cl>>COC(=O)c1ccc(NC(C)=O)c(N)c1.Cl,[Pd],CCO,,NN,O,test
US20030171370A1,COc1ccccc1C(OC(C)=O)c1ccc(C2=NC(C)(C)CO2)cc1>>COc1ccccc1Cc1ccc(C2=NC(C)(C)CO2)cc1,[Pd],CO,,O=C[O-].[NH4+],,test
US20100081644A1,CC(C)(CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)c1cc(NC(=O)C(C)(C)S(=O)(=O)CC2CCC(O)CC2)on1>>CC(C)(CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)c1cc(NC(=O)C(C)(C)S(=O)(=O)CC2CCC(=O)CC2)on1,,CCOCC,ClCCl,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20050010031A1,CNC(=O)C(Cc1ccc2ccccc2c1)N1CCN(C(=O)C(Cc2ccc(F)cc2)NC(=O)OC(C)(C)C)C(COC)C1.Cl>>CNC(=O)C(Cc1ccc2ccccc2c1)N1CCN(C(=O)C(N)Cc2ccc(F)cc2)C(COC)C1.Cl,,C1COCCO1,Cl,ClCCCl,,test
US20050054679A1,CCOC(=O)C(=O)C(C)Br.COc1ccc(NC(=N)c2ccc(Cl)cc2Cl)cc1>>CCOC(=O)c1nc(-c2ccc(Cl)cc2Cl)n(-c2ccc(OC)cc2)c1C,,CC(C)O,,O=C([O-])O.[Na+],,test
US20040220179A1,C[C@H](c1ccc(Cl)cc1)N1C(=O)C([Se]c2ccccc2)C(c2ccccc2)NC(=O)[C@@H]1c1ccc(Cl)cc1>>C[C@H](c1ccc(Cl)cc1)N1C(=O)C=C(c2ccccc2)NC(=O)[C@@H]1c1ccc(Cl)cc1,,C1CCOC1,,OO,,test
US04655816,CCOC(=O)C(F)(F)F.COC(=O)C(C(C)=O)=C(N)C(F)(F)F>>COC(=O)c1c(O)cc(C(F)(F)F)nc1C(F)(F)F,,C1CCOC1,CCCCCC,O,[Li]CCCC,test
US20140249133A1,CCOc1cc(F)c(Cn2nc(-c3ncc(OCCO[Si](C)(C)C(C)(C)C)c(Nc4ccncc4)n3)c3ccccc32)c(F)c1>>CCOc1cc(F)c(Cn2nc(-c3ncc(OCCO)c(Nc4ccncc4)n3)c3ccccc32)c(F)c1,,C1COCCO1,,Cl,O=C([O-])O.[Na+],test
US04665174,C=CCN.CCC1C(=O)C=CC1O>>C=CCNC1C=C(CC)C(=O)C1,,Cc1ccccc1,,,,test
US04299614,CCI.O=c1c(-c2cccc(C(F)(F)F)c2)c[nH]n1-c1ccc(F)cc1>>CCn1cc(-c2cccc(C(F)(F)F)c2)c(=O)n1-c1ccc(F)cc1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20150110809A1,CN1CCC(C=O)CC1.COC(=O)CC#N.NC(N)=S>>CN1CCC(c2nc(S)[nH]c(=O)c2C#N)CC1,,CCO,,C1CCNCC1,,test
US20080119466A1,Nc1ccc(-n2cnc3ccncc32)cc1.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>O=C(Nc1ccc(-n2cnc3ccncc32)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1,,ClCCl,,,,test
US20130053364A1,CCN(CC)C/C=C\c1cc(F)ccc1S(=O)(=O)Cc1ccc(Br)c(OC)c1C(=O)OC.OB(O)c1ccoc1>>CCN(CC)C/C=C\c1cc(F)ccc1S(=O)(=O)Cc1ccc(-c2ccoc2)c(OC)c1C(=O)OC,,C1COCCO1,O,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],test
US20080214580A1,CCOC(=O)c1nc(-n2cnc3ccc(F)cc32)nc(NC2CCOCC2)c1[N+](=O)[O-]>>CCOC(=O)c1nc(-n2cnc3ccc(F)cc32)nc(NC2CCOCC2)c1N,[Pd],CCO,,[H][H],,test
US20100105656A1,c1cnc2ccc(Cn3nnc4ncc(-c5cnn(CCOC6CCCCO6)c5)nc43)cc2c1>>OCCn1cc(-c2cnc3nnn(Cc4ccc5ncccc5c4)c3n2)cn1,,ClCCl,,C1COCCO1,Cl,test
US20100120615A1,COc1ccc(B(O)O)cc1.Cc1cc(Oc2ccc(Br)cc2)c(C)cc1N>>COc1ccc(-c2ccc(Oc3cc(C)c(N)cc3C)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCCCO,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20040019042A1,CC(=O)Nc1cccc(N)c1.Nc1cccc(O)c1.O=C1c2cc(S(=O)(=O)Cl)ccc2-c2ccc(S(=O)(=O)Cl)cc21>>CC(=O)Nc1cccc(NS(=O)(=O)c2ccc3c(c2)C(=O)c2cc(S(=O)(=O)Nc4cccc(O)c4)ccc2-3)c1,,c1ccncc1,,,,test
US20020019529A1,Cc1c(-c2ccccc2)sc2c1c(=O)c(C(=O)C(C)C)cn2Cc1c(F)cccc1F.O=C1CCC(=O)N1Br>>CC(C)C(=O)c1cn(Cc2c(F)cccc2F)c2sc(-c3ccccc3)c(CBr)c2c1=O,,CCOC(C)=O,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20110098296A1,COC(=O)c1cc(N)ccc1F.O=C(Cl)c1c(F)cccc1F>>COC(=O)c1cc(NC(=O)c2c(F)cccc2F)ccc1F,,ClCCl,,,,test
US20120289500A1,CN1CCCC1=O.N#[N+]C=C([O-])C12CC3CC(CC1C3)C2.Nn1nc(N2CCOCC2)c2ccccc2c1=O>>O=C(CC12CC3CC(CC1C3)C2)Nn1nc(N2CCOCC2)c2ccccc2c1=O,,CCOC(C)=O,ClCCCl,,,test
US20100261698A1,COC(=O)OC.CS(=O)(=O)NCc1cncc(-c2cc3ccc(Cl)cc3[nH]2)c1>>CN(Cc1cncc(-c2cc3ccc(Cl)cc3[nH]2)c1)S(C)(=O)=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070225292A1,CC(C)(C)OC(=O)N1CCCCC1CN.Nc1cccnc1C(=O)O>>CC(C)(C)OC(=O)N1CCCCC1CNC(=O)c1ncccc1N,,C1CCOC1,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040116689A1,COC(=O)Cc1n[nH]c2nc(NC(=O)C(C)C)nc(O)c12>>CC(C)C(=O)Nc1nc(O)c2c(CC(=O)O)n[nH]c2n1,,O,,[Na+].[OH-],,test
US05616599,CCCCc1nc(CO)c(C(=O)ON2C(=O)CCC2=O)n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1.COC(=O)[C@@H]1CCCN1>>CCCCc1nc(CO)c(C(=O)N2CCC[C@H]2C(=O)OC)n1Cc1ccc(-c2ccccc2C(=O)O)cc1,,CCN(CC)CC,,Cl,Cl,test
US20080051395A1,CN1CCc2ccc(N)cc2C1.O=C(Nc1cccc(-c2nn3ccccc3c2-c2ccnc(Cl)n2)c1)C(F)(F)F>>CN1CCc2ccc(Nc3nccc(-c4c(-c5cccc(NC(=O)C(F)(F)F)c5)nn5ccccc45)n3)cc2C1,Cl,CC(C)O,,,,test
US20110281842A1,C1CCNC1.CC1(C)OB(/C=C/CCl)OC1(C)C>>CC1(C)OB(/C=C/CN2CCCC2)OC1(C)C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05185351,CCCCc1ncc(/C=C(\Cc2cccs2)C(=O)OC)n1Cc1ccc(C(=O)OC)c2ccccc12>>CCCCc1ncc(C=C(Cc2cccs2)C(=O)O)n1Cc1ccc(C(=O)O)c2ccccc12,,CCO,O,[K+].[OH-],,test
US04782156,C#C.ClCCCl.O=C(Cl)c1cc(F)c(Cl)cc1Cl>>O=C(C=CCl)c1cc(F)c(Cl)cc1Cl,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20160159774A1,CC(C)(C)OC(=O)N1CC2(CC(N)C2)C1.Fc1cnc(Cl)nc1Cl>>CC(C)(C)OC(=O)N1CC2(CC(Nc3nc(Cl)ncc3F)C2)C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05824691,CC(C)(C)O.COC(=O)c1cc(CCC(=O)O)cc(-n2cccc2)c1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)NCCOC(=O)c1cccc(-n2cccc2)c1,,O,,CCN(CC)CC,CCOC(C)=O,test
US20090130117A1,CC(C)(C)OC(=O)N1CCC(N)CC1.COc1ccc(C(C)C)cc1-c1cc(C(=O)O)c(OCc2ccccc2)cc1OCc1ccccc1>>COc1ccc(C(C)C)cc1-c1cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)c(OCc2ccccc2)cc1OCc1ccccc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090233896A1,N#Cc1ccc(-c2cnc(Cl)s2)cn1.Nc1cccc(Cl)n1>>Cc1ccc(-c2cnc(Nc3cccc(Cl)n3)s2)cn1,,C1COCCO1,,[H-].[Na+],,test
US20100310512A1,Brc1ccc2c(c1)COCc1cc(Br)ccc1-2.CCCC[Sn](C=COCC)(CCCC)CCCC.O=C1CCC(=O)N1Br>>O=C(CBr)c1ccc2c(c1)COCc1cc(Br)ccc1-2,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O,,test
US20100120880A1,CCI.Cc1csc2nc3ccccc3n12>>CC[n+]1c2ccccc2n2c(C)csc21.[I-],,CC(C)=O,,,,test
US20040235867A1,Clc1nccc2c1CCN2>>Clc1nccc2[nH]ccc12,O=[Mn]=O,C1CCOC1,,,,test
US20070287725A1,CCOCc1nc2c(Cl)nc3ccccc3c2n1CCN1C(C)=NOC12CCCC2.N>>CCOCc1nc2c(N)nc3ccccc3c2n1CCN1C(C)=NOC12CCCC2,,CO,,,,test
US20090042892A1,BrC(Br)(Br)Br.CSc1ncc(Br)c(CO)n1>>CSc1ncc(Br)c(CBr)n1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150045368A1,CC1(C)OC(=O)N(C2CCC(Nc3ccc(C#N)cc3[N+](=O)[O-])CC2)[C@H]1c1ccc(F)cc1>>CC1(C)OC(=O)N(C2CCC(Nc3ccc(C#N)cc3N)CC2)[C@H]1c1ccc(F)cc1,,CCO,,Cl[Sn]Cl,,test
US20020119260A1,CCCCCc1ccc(-c2cc(F)cc(F)c2)cc1.O=CN1CCCCC1>>CCCCCc1ccc(-c2cc(F)c(C=O)c(F)c2)cc1,,C1CCOC1,,O,[Li]CCCC,test
US20030220304A1,COc1ccc(Br)c(C=O)c1OC(C)=O>>COc1ccc(Br)c(C=O)c1O,,CO,,O=C([O-])O.[Na+],,test
US20140038926A1,Brc1nccs1.COC(=O)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1cccc(C(F)(F)F)c1)C2>>O=C(c1nccs1)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1cccc(C(F)(F)F)c1)C2,,CCOCC,,O,[Li]CCCC,test
US20100166699A1,C[C@H](c1ccccc1)N(C)C([PH2]=O)(c1ccccc1)c1ccccc1.Cc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1-c1ccc(C(=O)c2ccc(Cl)cc2)cn1>>Cc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1-c1ccc(C(=CN(C)C(C)c2ccccc2)c2ccc(Cl)cc2)cn1,,C1CCOC1,,[Li]CCCC,,test
US20070054892A1,C=CCn1c(C#N)c(-c2ccccc2)c2cc(OC)ccc2c1=O>>COc1ccc2c(=O)[nH]c(C#N)c(-c3ccccc3)c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,CCN(CC)CC,O=CO,test
US20090062363A1,CCOC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccccc1>>CCOC(=O)c1ccc2c(c1)C(C)C(C)N2Cc1ccccc1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20090181941A1,CC(C)(N)c1ccc(-c2cncc(Br)c2)cc1.ClCCOCCCl>>CC(C)(c1ccc(-c2cncc(Br)c2)cc1)N1CCOCC1,,CN(C)C=O,,,,test
US20010001799A1,CCOc1ccc(C=O)cc1OCC.O=[N+]([O-])O>>CCOc1cc(C=O)c([N+](=O)[O-])cc1OCC,,ClCCCl,,,,test
US20120115811A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)O.Cn1nc(-c2ccncc2)cc1N>>Cn1nc(-c2ccncc2)cc1NC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)OC(C)(C)C,,c1ccncc1,,ClCCCl,,test
US20070276000A1,CCOC(=O)CC(Cc1cccc(OC)c1)C(C)C>>COc1cccc(CC(CC(=O)O)C(C)C)c1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20090097096A1,C=CCBr.CCOP(OCC)OCC>>C=CCP(=O)(OCC)OCC,,ClC(Cl)Cl,,,,test
US07728014B2,CCOC(=O)/C(=C/C=C/c1ccc(C)cc1)N=[N+]=[N-].c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CCOC(=O)C(=CC=Cc1ccc(C)cc1)N=P(c1ccccc1)(c1ccccc1)c1ccccc1,,CCOCC,,,,test
US20070244119A1,CCOC(=O)c1cc(-c2nnc([C@@](C)(Cc3ccccc3)NC(=O)OC(C)(C)C)o2)cc(C2(C#N)CCCC2)c1>>CC(C)(C)OC(=O)N[C@](C)(Cc1ccccc1)c1nnc(-c2cc(C(=O)O)cc(C3(C#N)CCCC3)c2)o1,,C1CCOC1,O,[Li]O,,test
US20040014763A1,O=C(O)/C=C/C=C/C1CCNCC1.O=C(OCC1c2ccccc2-c2ccccc21)ON1C(=O)CCC1=O>>O=C(O)/C=C/C=C/C1CCN(C(=O)OCC2c3ccccc3-c3ccccc32)CC1,,O=C([O-])O,[Na+],C1CCOC1,,test
US20050137226A1,Ic1ccc(Oc2ccccc2)cc1.OC1CN2CCC1CC2>>c1ccc(Oc2ccc(OC3CN4CCC3CC4)cc2)cc1,,CCOC(C)=O,Cc1ccccc1,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US20010039348A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)Nc1cc(Cl)c(OCCO)c(Cl)c1>>CC(=O)OCCOc1c(Cl)cc(NC(=O)OC(C)(C)C)cc1Cl,,c1ccncc1,,,,test
US20080306112A1,CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3ccc(OC(F)F)cc32)CC1.Cl>>Cl.O=c1[nH]c2ccc(OC(F)F)cc2n1C1CCNCC1,,CCO,CO,,,test
US20070179173A1,Clc1ccc(CBr)cc1.O=Cc1cc2ccccc2[nH]c1=O>>O=Cc1cc2ccccc2n(Cc2ccc(Cl)cc2)c1=O,,CCOC(C)=O,O,CN(C)C=O,[H-].[Na+],test
US20100056568A1,BrCc1ccccc1.O=c1[nH]ccc2cc(Br)ccc12>>Brc1ccc2c(OCc3ccccc3)nccc2c1,,Cc1ccccc1,,,,test
US20110152245A1,CC(C)(C)OC(=O)N1CCC(c2ccc(N)cc2)C1.O=C=Nc1ccccc1>>CC(C)(C)OC(=O)N1CCC(c2ccc(NC(=O)Nc3ccccc3)cc2)C1,,ClCCl,,,,test
US20090181950A1,COC(=O)/C=C/c1ccc2cc(Cc3ccccc3)cc(N3CCN(C(=O)OC(C)(C)C)CC3)c2n1>>COC(=O)/C=C/c1ccc2cc(Cc3ccccc3)cc(N3CCNCC3)c2n1,,ClCCl,,Cc1ccccc1,O=C(O)C(F)(F)F,test
US20100120741A1,COC(OC)N(C)C.Cc1ccc(Cl)cc1[N+](=O)[O-]>>CN(C)/C=C/c1ccc(Cl)cc1[N+](=O)[O-],,CN(C)C=O,,,,test
US20080119457A1,N#Cc1ccc(F)cc1NC1CCOCC1.NN>>N#Cc1ccc(NN)cc1NC1CCOCC1,,C1COCCO1,,O=C([O-])O.[Na+],,test
US20030144297A1,CCc1nc(-c2ccc(Cl)cc2Cl)c(CC)nc1N[C@H]1c2ccccc2C[C@H]1O.O=C(O)c1ccc([N+](=O)[O-])cc1>>CCc1nc(-c2ccc(Cl)cc2Cl)c(CC)nc1N[C@H]1c2ccccc2C[C@@H]1OC(=O)c1ccc([N+](=O)[O-])cc1,,c1ccccc1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030153599A1,CCOC(=O)C1CCc2ccc(O)cc2O1.O=C1CCC(=O)N1Cl>>CCOC(=O)C1CCc2cc(Cl)c(O)cc2O1,,C1CCOC1,,,,test
US20090306066A1,CCc1nc(NNC(=O)[C@H](CC2CCCC2)CN(C=O)OCc2ccccc2)c(F)c(N2CCC2)n1>>CCc1nc(NNC(=O)[C@H](CC2CCCC2)CN(O)C=O)c(F)c(N2CCC2)n1,,CO,,,,test
US20110244531A1,CCOC(CC(C(=O)OC)C(C)C)OCC>>COC(=O)C(CC=O)C(C)C,,Cl,,,,test
US20160229814A1,C#CCn1c(=O)n(CC)c(=O)c2cc([N+](=O)[O-])ccc21>>C#CCn1c(=O)n(CC)c(=O)c2cc(N)ccc21,,CCO,,Cl[Sn]Cl,,test
US05925768,CCC(=O)Cl.Cc1ccccc1Cl>>CCC(=O)c1ccc(Cl)c(C)c1,,Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20110172245A1,CC(=O)OCC(=O)Cl.Cc1ccc(Oc2ccc3nc(N)sc3c2)cc1NC(=O)c1cccc(C(C)(C)C#N)c1>>Cc1ccc(Oc2ccc3nc(NC(=O)CO)sc3c2)cc1NC(=O)c1cccc(C(C)(C)C#N)c1,,c1ccncc1,,,,test
US20010034343A1,COC(=O)c1cc(Cn2cnnn2)ccc1OC>>COc1ccc(Cn2cnnn2)cc1C(=O)O,,CCCCCC,CCOC(C)=O,[Li+].[OH-],,test
US03944675,COc1ccc(N)cc1.O=C(Cl)C12CC3CC(CC(C3)C1)C2>>COc1ccc(NC(=O)C23CC4CC(CC(C4)C2)C3)cc1,,ClC(Cl)Cl,,,,test
US20120295863A1,C#CCCCC.COc1ccc(CNc2ncnc3c2ncn3[C@@H]2O[C@H](CN=[N+]=[N-])[C@@H](O)[C@H]2O)cc1>>CCCCc1cn(C[C@H]2O[C@@H](n3cnc4c(NCc5ccc(OC)cc5)ncnc43)[C@H](O)[C@@H]2O)nn1,,CC(C)(C)O,O,O=C(CO)O[CH][C@@H](O)CO,C[O-].[Na+],test
US20110201647A1,Cl.O=C(NCc1ccc(F)c(-c2ccncc2)c1)C(F)(F)F>>Cl.O=C(NCc1ccc(F)c(C2CCNCC2)c1)C(F)(F)F,[Pt],CO,,,,test
US20120157430A1,CC1(C)OB(c2ccc(C=O)nc2)OC1(C)C.COc1c(C(C)NC(=O)OC(C)(C)C)cc(Cl)c(C)c1Br>>COc1c(C(C)NC(=O)OC(C)(C)C)cc(Cl)c(C)c1-c1ccc(C=O)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,N#N,O=C([O-])[O-].[K+].[K+],test
US20030166946A1,CC(C)n1cc(-c2ccc(F)cc2)c2ccccc21.CN(C)C=O>>CC(C)n1c(C=O)c(-c2ccc(F)cc2)c2ccccc21,,O,,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US20160272584A1,CN1CCC(O)CC1.COc1ccc(C(=O)Nc2ccc(-c3ccc(O)cc3)cn2)cc1-c1cccc(OC(C)=O)c1>>COc1cccc(-c2cc(C(=O)Nc3ccc(-c4ccc(OC5CCN(C)CC5)cc4)cn3)ccc2OC)c1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070173486A1,CCN(CC)CC.CCOC(C)=O.Clc1ccc(C(OC2CNC2)c2ccccc2Cl)cc1>>O=C(c1ccncc1)N1CC(OC(c2ccc(Cl)cc2)c2ccccc2Cl)C1,,ClCCl,,Cl,,test
US20090298807A1,CC(C)(C)[Si](C)(C)Cl.OCC(F)c1cccc(Br)c1>>CC(C)(C)[Si](C)(C)OCC(F)c1cccc(Br)c1,,CN(C)C=O,,c1c[nH]cn1,,test
US20020119963A1,NC1CCC1.O=[N+]([O-])c1cn([N+](=O)[O-])cn1>>O=[N+]([O-])c1cn(C2CCC2)cn1,,CO,,,,test
US20150297587A1,Cc1ccc(S(=O)(=O)n2cc(-c3ccc(CN4CCN(C)CC4)cc3)c3cc(Br)cnc32)cc1.O=Cc1ccc(B(O)O)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3ccc4[nH]ccc4c3)c3cc(-c4ccc(C=O)cc4)cnc32)cc1,,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20150299230A1,CS(=O)(=O)c1cc([N+](=O)[O-])c(C(=O)O)cc1F.OCCNCCO>>CS(=O)(=O)c1cc([N+](=O)[O-])c(C(=O)O)cc1N(CCO)CCO,,CS(C)=O,,,,test
US20060281753A1,CC(C)(C)OC(=O)N1CC[C@@H](CN(Cc2ccccc2)Cc2ccccc2)[C@H](O)C1>>O[C@@H]1CNCC[C@H]1CN(Cc1ccccc1)Cc1ccccc1,,CC(C)O,,,,test
US20110275797A1,COC(=O)c1ccc(-c2ccco2)cc1NC(=O)c1cncc(-c2ccccc2)c1>>O=C(Nc1cc(-c2ccco2)ccc1C(=O)O)c1cncc(-c2ccccc2)c1,,C1COCCO1,,[Na+].[OH-],,test
US20100311790A1,C=CCCCCCCBr.O=C(NCc1cccc(O)c1F)c1ccc2ncccc2c1>>C=CCCCCCCOc1cccc(CNC(=O)c2ccc3ncccc3c2)c1F,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20070004675A1,O=[N+]([O-])c1ccc(Oc2ccnc3cc(Br)sc23)c(F)c1>>Nc1ccc(Oc2ccnc3cc(Br)sc23)c(F)c1,[Fe],CCO,,O,[Cl-].[NH4+],test
US20120035053A1,COC1=CC(CC2OCCO2)C=C(OC)C1>>O=C1CC(=O)CC(CC2OCCO2)C1,,C1CCOC1,Cl,O=C([O-])[O-].[K+].[K+],,test
US06262199B1,C1CCOC1.CCCCCC.[Li]CCCC>>CC1=Cc2ccccc2C1,,C1CCOC1,,,,test
US20100267666A1,CC(O)CN.COc1cc(-c2cnc3[nH]cc(C(=O)O)c3n2)cc(OC)c1OC>>COc1cc(-c2cnc3[nH]cc(C(=O)NCC(C)O)c3n2)cc(OC)c1OC,,CN(C)C=O,,,,test
US20090082329A1,CC1(C)C(=O)N(c2ccc(SC(F)(F)F)cc2)C(=O)N1Cc1ccnc(N)n1.O=C(Cl)Oc1ccccc1>>CC1(C)C(=O)N(c2ccc(SC(F)(F)F)cc2)C(=O)N1Cc1ccnc(NC(=O)Oc2ccccc2)n1,,C1CCOC1,CCOC(C)=O,c1ccncc1,,test
US20120230951A1,COC(=O)N[C@H](C(=O)N1CC(F)(F)C[C@H]1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1)C(C)C.COC(=O)N[C@H]1CCc2ccn3c2C1C(=O)C[C@H](c1ncc(-c2cnc(Cl)nc2)[nH]1)C3>>COC(=O)N[C@H]1CCc2ccn3c2C1C(=O)C[C@H](c1ncc(-c2cnc(-c4ccc(-c5cnc([C@@H]6CCCN6C(=O)[C@@H](NC(=O)OC)C(C)C)[nH]5)cc4)nc2)[nH]1)C3,,CCO,O,Cc1ccccc1,O=C([O-])O.[Na+],test
US20150210652A1,CC(C)(C)OC(=O)N1CC2CCC1CN2c1nc(-c2ccc(N3CCCC3)cc2)nc(C(Cl)(Cl)Cl)n1.Cl>>Cl.ClC(Cl)(Cl)c1nc(-c2ccc(N3CCCC3)cc2)nc(N2CC3CCC2CN3)n1,,ClC(Cl)Cl,,C1COCCO1,,test
US04555263,CCCCS.O=Cc1ccc([N+](=O)[O-])cc1>>CCCCSc1ccc(C=O)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100240658A1,COCC#Cc1cc(C(=O)O)ccc1-c1ccccc1C>>COCCCc1cc(C(=O)O)ccc1-c1ccccc1C,[Pd],CO,,,,test
US20080113984A1,COc1cc(-c2nnc(S)n2N)cc(OC)c1OC.Cc1ccc(C(=O)Cl)cc1[N+](=O)[O-]>>COc1cc(-c2nnc3sc(-c4ccc(C)c([N+](=O)[O-])c4)nn23)cc(OC)c1OC,,O=P(Cl)(Cl)Cl,,,,test
US20110245205A1,CC(C)(C)[Si](C)(C)Cl.O=[N+]([O-])c1cc(Br)cc(CO)c1>>CC(C)(C)[Si](C)(C)OCc1cc(Br)cc([N+](=O)[O-])c1,,CN(C)C=O,,c1c[nH]cn1,,test
US20090023753A1,CC(C)(C)OC(=O)Nc1ncsc1C(=O)Nc1ccc2c(c1)OC(F)(F)O2>>Nc1ncsc1C(=O)Nc1ccc2c(c1)OC(F)(F)O2,,ClCCl,O=C(O)C(F)(F)F,,,test
US20120208799A1,C#CCCN.O=C(Cl)N1CCOCC1>>C#CCCNC(=O)N1CCOCC1,,ClCCl,,CCN(CC)CC,Cl,test
US20160096827A1,COc1cc(Nc2ncnc(Cl)n2)ccc1N1CCN(C2COC2)CC1.C[C@H](O)C(=O)N1CC[C@H](Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C#N)[C@H](F)C1>>COc1cc(Nc2ncnc(-c3ccc(O[C@H]4CCN(C(=O)[C@H](C)O)C[C@H]4F)c(C#N)c3)n2)ccc1N1CCN(C2COC2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20150141400A1,C=O.CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2cc(CN3CCNCC3)c(C(F)(F)F)cc2c1=O>>CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2cc(CN3CCN(C)CC3)c(C(F)(F)F)cc2c1=O,,C1CCOC1,CCOC(C)=O,O=C([O-])O.[Na+],,test
US04520134,CC(=O)Nc1ccc(OC(C)=O)cc1>>CCNc1ccc(O)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],[Cl-].[NH4+],test
US20120214837A1,COc1ccc2ncc(CO)cc2c1.O=S(Cl)Cl>>COc1ccc2ncc(CCl)cc2c1.Cl,,ClCCl,,,,test
US20070249670A1,CCCCc1ccc(N=C=O)cc1.COC(=O)[C@@H](NC(=O)c1cc2ccccc2cc1N)C1CCCCC1>>CCCCc1ccc(NC(=O)Nc2cc3ccccc3cc2C(=O)N[C@H](C(=O)OC)C2CCCCC2)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20140121223A1,CC(=O)OC(C)C(Nc1cccc(C)c1C(=O)Nc1ccccc1)N1CCCCC1>>CC(=O)OC(C)c1nc2cccc(C)c2c(=O)n1-c1ccccc1,,CC#N,,,,test
US04942245,CCCc1c(OCCSc2nc3ccc(C(=O)OCC)cc3[nH]2)ccc(C(C)=O)c1O>>CCCc1c(OCCSc2nc3ccc(C(=O)O)cc3[nH]2)ccc(C(C)=O)c1O,,[Na+],[OH-],Cl,,test
US20020119983A1,O=CCCc1cc(-c2ccccc2)no1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>c1ccc(-c2cc(CCCN3CCN(C(c4ccccc4)c4ccccc4)CC3)on2)cc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20060235015A1,Nc1ccc(OC(F)(F)F)cc1.O=C1C(Cl)=C(c2ccccc2)C(=O)N1Cc1cccnc1>>O=C1C(Nc2ccc(OC(F)(F)F)cc2)=C(c2ccccc2)C(=O)N1Cc1cccnc1,,CC#N,,O,,test
US20060035905A1,CC(=O)[O-].CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12>>CC(=O)[O-].CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12,,CC(=O)O,,[Cl-].[Na+],,test
US20160046596A1,COc1cc(C=Nc2ccc(F)c(Cl)c2)c(O)c(C)n1.C[Si](C)(C)C#N>>COc1cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc2c(C)n1,,ClCCl,,,,test
US04956382,CN(CCc1ccc([N+](=O)[O-])cc1)Cc1cc2cc([N+](=O)[O-])ccc2s1>>CN(CCc1ccc(N)cc1)Cc1cc2cc(N)ccc2s1,,CCO,,,,test
US20020198195A1,COC(=O)c1cccc(O)c1.OCCc1ccc(Cl)cc1Cl>>COC(=O)c1cccc(OCCc2ccc(Cl)cc2Cl)c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04229471,CCCCC(CC)CNC(=O)CC(C)O>>C/C=C/C(=O)NCC(CC)CCCC,,CCCCCC,,,,test
US20030199525A1,COc1cc(-n2nc(C3=CCN(C(=O)OC(C)(C)C)CC3)c3ncnc(N)c32)ccc1[N+](=O)[O-]>>COc1cc(-n2nc(C3CCN(C(=O)OC(C)(C)C)CC3)c3ncnc(N)c32)ccc1N,[Pd],CO,,,,test
US05216047,Nc1ccccc1.O=C1C=CC(=O)O1>>O=C1C=CC(=O)N1c1ccccc1,,c1ccccc1,,,,test
US20100311730A1,COc1ccc(-c2cnc(Nc3cnc(C#N)cn3)cc2NC[C@@H]2CN(C(=O)OC(C)(C)C)CCO2)cc1>>COc1ccc(-c2cnc(Nc3cnc(C#N)cn3)cc2NC[C@@H]2CNCCO2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160122323A1,CN(C)C/C=C/C(=O)Nc1ccc(C(=O)Nc2cccc(Nc3ncc(C#N)c(-c4cn(S(=O)(=O)c5ccccc5)c5ccccc45)n3)c2)cc1>>CN(C)C/C=C/C(=O)Nc1ccc(C(=O)Nc2cccc(Nc3ncc(C#N)c(-c4c[nH]c5ccccc45)n3)c2)cc1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20120165305A1,N#CCC1(n2cc(-c3cnn4c(-c5cccc(NC(=O)NCC(F)(F)F)c5)cnc4c3)cn2)CNC1.O=C=Nc1ccccc1>>N#CCC1(n2cc(-c3cnn4c(-c5cccc(NC(=O)NCC(F)(F)F)c5)cnc4c3)cn2)CN(C(=O)Nc2ccccc2)C1,,CN(C)C=O,CO,CCN(CC)CC,,test
US05141945,CC(=O)OC(C)=O.Cc1c2n(c3ccc(Cl)cc13)C(=O)C(C(O)c1ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c1C)CC2>>CC(=O)OC(c1ncn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c1C)C1CCc2c(C)c3cc(Cl)ccc3n2C1=O,,ClCCl,,c1ccncc1,,test
US20070015766A1,CC(C)(C)OC(=O)NCCC(=O)O.CC[C@H](NC(=O)c1c(CN2CCNCC2)c(-c2ccccc2)nc2ccccc12)c1ccccc1>>CC[C@H](NC(=O)c1c(CN2CCN(C(=O)CCNC(=O)OC(C)(C)C)CC2)c(-c2ccccc2)nc2ccccc12)c1ccccc1,,ClCCl,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20090227622A1,Nc1cc(C(=O)N2CCOCC2)cc(C(F)(F)F)c1>>Nc1cc(CN2CCOCC2)cc(C(F)(F)F)c1,,C1CCOC1,,,,test
US20050192325A1,[N-]=[N+]=CC(=O)OC/C=C/c1ccc(NC(=O)OCc2ccccc2)cc1F>>O=C(Nc1ccc([C@@H]2[C@H]3COC(=O)[C@H]32)c(F)c1)OCc1ccccc1,,Cc1ccccc1,,,,test
US20100184739A1,COc1ccc2c(=O)c(C(=O)Nc3cc(O)c(C(C)(C)C)cc3C(C)(C)C)c[nH]c2c1>>CC(C)(C)c1cc(C(C)(C)C)c(NC(=O)c2c[nH]c3cc(O)ccc3c2=O)cc1O,,ClCCl,,BrB(Br)Br,,test
US20040077640A1,BrCc1ccccc1.c1ccc(-c2ccc(-c3c[nH]c(C4CCNCC4)n3)cc2)cc1>>c1ccc(CN2CCC(c3nc(-c4ccc(-c5ccccc5)cc4)c[nH]3)CC2)cc1,,CC#N,,CCN(CC)CC,Cl,test
US05998433,CC(c1ccccc1)c1ccc(C(=O)N2CCc3cc(CN(C)C)oc3C2)cc1.Cl>>CC(c1ccccc1)c1ccc(C(=O)N2CCc3cc(CN(C)C)oc3C2)cc1.Cl,,CCOC(C)=O,CO,,,test
US20120291159A1,C=C(c1cc(Cl)cc(Cl)c1)C(F)(F)F.O=[N+]([O-])c1cccc(C(Cl)=NO)c1>>O=[N+]([O-])c1cccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20100331335A1,COC(=O)Cc1ccc(OCCCN2CCCCC2)cc1>>O=C(O)Cc1ccc(OCCCN2CCCCC2)cc1,,CC(=O)O,,Cl,,test
US05403842,BrBr.CC(=O)c1cccc2c(=O)c(C)c(-c3ccccc3)oc12>>Cc1c(-c2ccccc2)oc2c(C(=O)CBr)cccc2c1=O,,ClC(Cl)Cl,,,,test
US20130203593A1,CC(C)c1cccc(F)c1NC(=S)NN.O=Cc1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1>>CC(C)c1cccc(F)c1NC(=S)N/N=C/c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1,,CO,,,,test
US20070020244A1,NNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21.O=S(=O)(O)CCN1CCOCC1>>O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21,,CS(C)=O,,CCN=C=NCCCN(C)C,,test
US20120022045A1,C1CCOC1.C=CCOCC1CO1.C=C[Mg]Br>>C=CCCC(O)COCC=C,[Cu]I,,,,,test
US20090270351A1,COC(=O)c1ccc(C(C)=O)cc1.COP([O-])OC>>COC(=O)c1ccc(C(C)(O)P(=O)(OC)OC)cc1,,C1CCOC1,CCOC(C)=O,,,test
US20100041713A1,CC(C)c1cccc(-c2ccc(Cl)nc2)c1.SCc1ccccc1>>CC(C)c1cccc(-c2ccc(SCc3ccccc3)nc2)c1,,CN(C)C=O,,[H-].[Na+],,test
US20120077781A1,Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCOCCCC(=O)OC(C)(C)C)c2cc1C>>COC(=O)CCCOCCn1c2nc(=O)[nH]c(=O)c-2nc2cc(C)c(C)cc21,,CO,,CC(=O)Cl,,test
US20110098292A1,Cc1ccnc(N)c1.O=S(=O)(Cl)c1cc(-c2nc3ccccc3s2)cs1>>Cc1ccnc(NS(=O)(=O)c2cc(-c3nc4ccccc4s3)cs2)c1,,c1ccncc1,,,,test
US20070105784A1,CN(CCCN)CCCNC(=O)OC(C)(C)C.Cn1c2c3ccccc3nc-2c(Cl)c2ccccc21>>CN(CCCNC(=O)OC(C)(C)C)CCCNc1c2nc3ccccc3c-2n(C)c2ccccc12,,CCOCCO,,,,test
US04772600,CNc1ccc(N(C)C)cc1.O=C(O)Cn1c(-c2ccc(Cl)cc2)nc2cccnc21>>CN(C)c1ccc(N(C)C(=O)Cn2c(-c3ccc(Cl)cc3)nc3cccnc32)cc1,,CN(C)C=O,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US05885986,CCCN(CCC)Cc1cnc(-c2ncn3c2CN(C)C(=O)c2ccccc2-3)o1.Cl>>CCCN(CCC)Cc1cnc(-c2ncn3c2CN(C)C(=O)c2ccccc2-3)o1.Cl,,CCOC(C)=O,,,,test
US20110003836A1,O=C1OC(Cn2c3ccc(Br)cc3c3cc(Br)ccc32)CN1c1cccnc1>>OC(CNc1cccnc1)Cn1c2ccc(Br)cc2c2cc(Br)ccc21,,C1CCOC1,O,[Li]O,,test
US05674886,Fc1ccc2nonc2c1.Nn1cnnc1>>c1cc2nonc2cc1Nn1cnnc1,,CS(C)=O,,O,CC(C)(C)[O-].[K+],test
US20020065296A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(Cc2ccc(N)cc2)cc1.c1ccc(NCNc2ccccc2)cc1>>CC(C)(C)ONC(=O)c1ccc(Cc2ccc(N)cc2)cc1,,CCOCC,,C1CCOC1,,test
US04415572,COC=CC(=O)Cl.COc1ccc(C(=O)N2CCN(c3ccc(N)cc3)CC2)cc1OC>>COC=CC(=O)Nc1ccc(N2CCN(C(=O)c3ccc(OC)c(OC)c3)CC2)cc1,,c1ccccc1,,CCN(CC)CC,,test
US04479962,Cc1cccc(C)c1NCCNCC(O)COc1cccc2nn(Cc3ccccc3)cc12>>Cc1cccc(C)c1NCCNCC(O)COc1cccc2[nH]ncc12,[Pd],CO,,Cl,,test
US20080262036A1,Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(C)O.N#Cc1ccc(O)cc1Cl>>Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(C)Oc1ccc(C#N)c(Cl)c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080009515A1,CCOC(=O)c1cnc(N)c2c(COc3cc(-c4nnc(C)n4Cc4ccc(OC)cc4)ccc3C)csc12.NCCO>>COc1ccc(Cn2c(C)nnc2-c2ccc(C)c(OCc3csc4c(C(=O)NCCO)cnc(N)c34)c2)cc1,,CS(C)=O,O,,,test
US20080207616A1,CC(C)(C#N)c1cccc(C(=O)O)c1.Nc1ccc(Cl)c(N)c1>>CC(C)(C#N)c1cccc(C(=O)Nc2ccc(Cl)c(N)c2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040082583A1,COC(=O)Nc1nc2ccc(Oc3ccc([N+](=O)[O-])cc3)cc2s1>>COC(=O)Nc1nc2ccc(Oc3ccc(N)cc3)cc2s1,,CN(C)C=O,,Cl[Sn]Cl,,test
US20060258714A1,C=CCc1ccc(Cl)c(-c2ccccc2Cl)c1O>>CC=Cc1ccc(Cl)c(-c2ccccc2Cl)c1O,Cc1ccccc1[P](c1ccccc1C)(c1ccccc1C)[Pd](Cl)(Cl)[P](c1ccccc1C)(c1ccccc1C)c1ccccc1C,ClCCl,,,,test
US20140121199A1,COC(=O)C(C)(C)CN1CCN(C2=Nc3ccc(C)cc3Oc3sc(Cl)cc32)CC1>>Cc1ccc2c(c1)Oc1sc(Cl)cc1C(N1CCN(CC(C)(C)C(=O)O)CC1)=N2,,CC(C)O,O,Cl,[Na+].[OH-],test
US20070043061A1,O=C(C=P(c1ccccc1)(c1ccccc1)c1ccccc1)CCl.O=Cc1ccccc1>>O=C(C=Cc1ccccc1)CCl,,Cc1ccccc1,,,,test
US05726165,COC(=O)COc1ccc(CC(C)NCC(O)COc2ccc(O)c(O)c2)cc1.Cl>>CC(Cc1ccc(OCC(=O)O)cc1)NCC(O)COc1ccc(O)c(O)c1.Cl,,O,,Cl,,test
US04536391,N#Cc1ccc(CCCN2C(=O)c3ccccc3C2=O)cc1>>N#Cc1ccc(CCCN)cc1,,CO,,NN,O,test
US05750735,CC(=O)S[C@@H]1CO[C@@H](CO)C1.O=C(NOCc1ccccc1)OCC(Cl)(Cl)Cl>>CC(=O)S[C@@H]1CO[C@@H](CN(OCc2ccccc2)C(=O)OCC(Cl)(Cl)Cl)C1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030009056A1,O=C(O)[C@@H]1CCCN1.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=C(O)[C@@H]1CCCN1S(=O)(=O)c1ccccc1[N+](=O)[O-],,C1CCOC1,O,[Na+].[OH-],,test
US20040024034A1,CCCc1cc(OCCc2nc(-c3ccccc3)oc2C)ccc1OC(C)(C)C(=O)OCC>>CCCc1cc(OCCc2nc(-c3ccccc3)oc2C)ccc1OCC(=O)O,,CO,,[Na+].[OH-],,test
US20090192190A1,CCOC(C)=O.CI.O=C(O)c1cc(Br)cc(Br)c1O>>COC(=O)c1cc(Br)cc(Br)c1OC,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100009986A1,CC(=O)OC(C)=O.NCCc1c[nH]c2ccccc12>>CC(=O)NCCc1c[nH]c2ccccc12,,C1CCOC1,,CCN(CC)CC,,test
US20060106051A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(N)c1cccc(B2OC(C)(C)C(C)(C)O2)c1>>CC(C)(C)OC(=O)NC(C)(C)c1cccc(B2OC(C)(C)C(C)(C)O2)c1,,ClC(Cl)Cl,,CC#N,,test
US04960784,CC(C)(CC(=O)O)Sc1cccc(Cl)c1>>CC1(C)CC(=O)c2ccc(Cl)cc2S1,,CCOCC,O,,,test
US20050107435A1,CS(=O)(=O)Cl.OCC1CC(c2ccc(Br)s2)=NO1>>CS(=O)(=O)OCC1CC(c2ccc(Br)s2)=NO1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20060135537A1,Cc1cnc2c(-c3cc(S(C)=O)ncn3)c(N)nn2c1.NC(=O)C1CCCNC1>>Cc1cnc2c(-c3cc(N4CCCC(C(N)=O)C4)ncn3)c(N)nn2c1,,CN1CCCC1=O,,,,test
US20150252032A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@@]1(C(=O)O)CCCN1.Cl>>CC(C)(C)OC(=O)N1CCC[C@@]1(C)C(=O)O.Cl,,CC#N,,O,,test
US20060189621A1,CN1CCNCC1.CS(=O)(=O)OCc1cc(-c2ccc3c(c2)CCO3)nn(CC2CC2)c1=O>>CN1CCN(Cc2cc(-c3ccc4c(c3)CCO4)nn(CC3CC3)c2=O)CC1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20150291595A1,BrBr.CC(C)(C)OC(=O)N[C@@H](CCO)c1nn2cccc2c(=O)n1-c1ccccc1>>CC(C)(C)OC(=O)N[C@@H](CCBr)c1nn2cccc2c(=O)n1-c1ccccc1,,ClCCl,O,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050164235A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.OCCOCCOCCOCCO>>CC(C)(C)[Si](OCCOCCOCCOCCO)(c1ccccc1)c1ccccc1,,CN(C)C=O,,c1c[nH]cn1,,test
US20040077619A1,CCOC(=O)c1ccc2nn(CC)nc2c1>>CCn1nc2ccc(CO)cc2n1,,Cc1ccccc1,,CC(C)C[AlH]CC(C)C,,test
US20110230464A1,C1NCC2COCC1N2.CCn1c(C=O)nc2c(N3CCOCC3)nc(Cl)nc21>>CCn1c(CN2CC3COCC(C2)N3)nc2c(N3CCOCC3)nc(Cl)nc21,,ClCCCl,,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140024650A1,CC(C)(C)OC(=O)N[C@H]1CCOC[C@@H]1COc1cc(F)c(-n2cc(Cl)cn2)c(F)c1.Cl>>Cl.N[C@H]1CCOC[C@@H]1COc1cc(F)c(-n2cc(Cl)cn2)c(F)c1,,CO,,CCO,,test
US20050233253A1,CCc1cc(CC)c2sc3ccccc3c(=O)c2c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.O=S(c1ccccc1)c1ccccc1>>CCc1cc(CC)c2sc3ccc([S+](c4ccccc4)c4ccccc4)cc3c(=O)c2c1.O=S(=O)([O-])C(F)(F)F,,ClCCl,,,,test
US20110118238A1,CN1CCC(N)CC1.Nc1ccc(C(=O)O)cc1Cl>>CN1CCC(NC(=O)c2ccc(N)c(Cl)c2)CC1,,CCOCC,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100048636A1,CCOC(CBr)OCC.O=C1NC(=O)c2ccccc21>>CCOC(CN1C(=O)c2ccccc2C1=O)OCC,,CN(C)C=O,,[K],,test
US20080312286A1,CC(C)C1Cc2cc(O)c(Cl)c(Cl)c2C1=O.N#Cc1ccc(CBr)cc1>>CC(C)C1Cc2cc(OC(=O)c3ccc(C#N)cc3)c(Cl)c(Cl)c2C1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160257645A1,CN(C(=O)[C@@H](N)Cc1ccccc1)c1ccc(OCC(N)=O)cc1.Cc1ccccc1S(=O)(=O)N=C=O>>Cc1ccccc1S(=O)(=O)NC(=O)N[C@@H](Cc1ccccc1)C(=O)N(C)c1ccc(OCC(N)=O)cc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US06358972B1,CN1CCC(c2c[nH]c3ccc(C=O)cc23)CC1.Nc1ccc(Cl)cc1N>>CN1CCC(c2c[nH]c3ccc(-c4nc5ccc(Cl)cc5[nH]4)cc23)CC1,,O=[N+]([O-])c1ccccc1,,,,test
US09324949B2,COc1ccc(Cl)cc1-c1cnccc1N>>Clc1ccc2oc3ccncc3c2c1,,CC(=O)O,,C1CCOC1,O,test
US05498774,CCOC(=O)c1cccn2cc(-c3ccccc3)nc12.O=C=NS(=O)(=O)Cl>>CCOC(=O)c1cccn2c(C#N)c(-c3ccccc3)nc12,,CC#N,,Br,CCN(CC)CC,test
US20160016951A1,CCCC[Sn](CCCC)(CCCC)c1nccn1C.Cn1cc(-c2ccc(-c3cncc4ccc(Cl)nc34)cc2)cn1>>Cn1cc(-c2ccc(-c3cncc4ccc(-c5nccn5C)nc34)cc2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20160115158A1,COc1cc(SC)ncc1[N+](=O)[O-].O=S([O-])OO>>COc1cc(S(C)(=O)=O)ncc1[N+](=O)[O-],,O,,CO,,test
US20100305096A1,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CNC3)n(C)c2n1.C[C@H](O)C(=O)O>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CN(C(=O)[C@H](C)O)C3)n(C)c2n1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020147334A1,CCOC(=O)CC(Cc1ccc(OCCc2cccc(NC)n2)cc1)c1nc(C)cs1>>CNc1cccc(CCOc2ccc(CC(CC(=O)O)c3nc(C)cs3)cc2)n1,,C1CCOC1,O,[Li+].[OH-],,test
US20160002248A1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.CN(C)C=O.O=C(O)c1cn(CCCCc2cc3cc(-c4ccccc4F)[nH]c3nn2)nn1>>O=C(NCc1ccccn1)c1cn(CCCCc2cc3cc(-c4ccccc4F)[nH]c3nn2)nn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04410534,CC(C)CCO.Cc1ccc(C(=O)c2ccc3n2CCCC3C(=O)O)cc1>>Cc1ccc(C(=O)c2ccc3n2CCCC3C(=O)OCCC(C)C)cc1,,CC(C)CCO,,Cl,,test
US04254127,O=C(CC1CCNCC1)c1ccc(F)cc1.O=c1[nH]c2ccccc2n1CCCCl>>O=C(CC1CCN(CCCn2c(=O)[nH]c3ccccc32)CC1)c1ccc(F)cc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20090156582A1,COC(=O)c1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1N.O=C(O)c1cnccn1>>COC(=O)c1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1NC(=O)c1cnccn1,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20120022056A1,Cc1ccc2c(N3CCN(CCc4cccc(Br)c4OC(C)C(N)=O)CC3)cccc2n1>>Cc1ccc2c(N3CCN(CCc4cccc5c4OC(C)C(=O)N5)CC3)cccc2n1,[Cu]I,CN1CCCC1=O,,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US20020052408A1,Oc1ccccc1.c1ccc(C2CO2)cc1>>OCC(Oc1ccccc1)c1ccccc1,,O,,[Na+].[OH-],,test
US20100256143A1,CC(C)(C)OC(=O)NCCc1nc(-c2cccc3c2ccn3S(=O)(=O)c2ccccc2)cc(N2CCOCC2)n1>>NCCc1nc(C2C=CC=C3C2=CCN3S(=O)(=O)c2ccccc2)cc(N2CCOCC2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100210680A1,BrBr.COc1ccc(CCC#N)c(C)c1>>COc1cc(C)c(CCC#N)cc1Br,,ClC(Cl)Cl,,CC(=O)[O-].[Na+],,test
US20080153810A1,CC(C)(C)OC(=O)N1CCN(S(C)(=O)=O)CC1.O=C(O)C(F)(F)F>>CS(=O)(=O)N1CCN(C(=O)C(F)(F)F)CC1,,ClCCl,,,,test
US20140094473A1,CC(C)(C)[C@@H](COS(C)(=O)=O)Nc1nc(Cl)ncc1F.CC([O-])=S>>CC(=O)SC[C@@H](Nc1nc(Cl)ncc1F)C(C)(C)C,,CN(C)C=O,,O,,test
US20100048564A1,CCOc1ccc2nc(COc3cccc(C(=O)OC)c3)n(C)c2c1.Cl>>CCOc1ccc2nc(COc3cccc(C(=O)O)c3)n(C)c2c1.Cl,,C1COCCO1,,Cl,[Na+].[OH-],test
US20040249159A1,COc1cccc(C2(CCCN(C)C)C(=O)NC(=O)CC2(C)C)c1.O=S(=O)(O)O>>COc1cccc(C2(CCCN(C)C)C(=O)NC(=O)CC2(C)C)c1.O=S(=O)(O)O,,CCO,,,,test
US20070197795A1,COC(=O)C(Cc1ccccc1)NC(N)=O>>O=C1NCC(Cc2ccccc2)N1,,Cl,ClCCl,CC(C)C[Al+]CC(C)C.[H-],,test
US20090048259A1,C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1c1nnc(Cl)c2ccccc12>>C[C@@H]1CNCCN1c1nnc(Cl)c2ccccc12,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20130029986A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C(=O)c1c[nH]c2ccc(Br)cc12>>CCOC(=O)C(=O)c1cn(C(=O)OC(C)(C)C)c2ccc(Br)cc12,CN(C)c1ccncc1,ClCCl,,,,test
US05432182,C=Cc1cccc2cc(C(=O)CCC)c(=O)[nH]c12.ClC(Cl)Cl.O=P(Cl)(Cl)Cl>>C=Cc1cccc2c(Cl)c(C(=O)CCC)cnc12.CCl,,O=P(Cl)(Cl)Cl,,,,test
US05952511,CCOC(CBr)OCC.O=C1Nc2ccccc2C1=O>>CCOC(CN1C(=O)C(=O)c2ccccc21)OCC,,CS(C)=O,,Cl,CC(C)(C)[O-].[K+],test
US20100152185A1,NNC(=O)c1ccc(OCc2ccc3ccccc3n2)cc1C1(c2ccccc2)CC2CCC1C2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>FC(F)(F)c1nnc(-c2ccc(OCc3ccc4ccccc4n3)cc2C2(c3ccccc3)CC3CCC2C3)o1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20060264429A1,CN1C(=O)COc2ccc(CCCl)cc21.Cc1ccc2c(N3CCNCC3)cc(F)cc2n1.Cl>>Cc1ccc2c(N3CCN(CCc4ccc5c(c4)N(C)C(=O)CO5)CC3)cc(F)cc2n1.Cl,,ClCCl,,,,test
US20110086854A1,CC(C)(C)CC1CNC(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.O=C(O)c1ccc(S(=O)(=O)Cl)cc1>>CC(C)(C)C[C@@H]1CN(S(=O)(=O)c2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US05559266,CC(Cl)OC(=O)Cl.COCCO>>COCCC(C)Cl.O=C(O)O,,ClC(Cl)Cl,,c1ccncc1,,test
US20060160815A1,CCC1c2cccn2-c2ccc(F)cc2N1S(=O)(=O)c1ccc(O)c(C)c1.O=C1CCC(=O)N1Br>>CCC1c2ccc(Br)n2-c2ccc(F)cc2N1S(=O)(=O)c1ccc(O)c(C)c1,,ClCCl,,,,test
US20080306040A1,CC(C)(C)OC(=O)NCCC[C@@H](CCC(=O)O)NC(=O)OCc1ccccc1.CC(C)(C)OC(=O)NCCC[C@@H](CN)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCC[C@@H](CC(=O)NC[C@H](CCCNC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20110207711A1,BrCc1ccccc1.Oc1cc(Br)c2ccnn2c1>>Brc1cc(OCc2ccccc2)cn2nccc12,,CN(C)C=O,,[H-].[Na+],,test
US20040063705A1,COc1ccc([N+](=O)[O-])cc1CCN(C)C>>COc1ccc(N)cc1CCN(C)C,[Pd],CCO,,,,test
US05215983,C=CCOC(=O)N1C[C@@H](C(C)(C)C)C[C@@]1(Cn1ccn2nccc12)O[SiH](C)C>>C=CCOC(=O)N1C[C@H](O)C[C@H]1Cn1ccn2nccc12,,CO,,Cl,C[O-].[Na+],test
US20120009151A1,CS(=O)(=O)N1CCC(Nc2nc(Nc3ccc(F)c(C(=O)N4CCOCC4)c3)nc(OCC(F)(F)F)n2)CC1>>CS(=O)(=O)N1CCC(Nc2nc(Nc3ccc(F)c(CN4CCOCC4)c3)nc(OCC(F)(F)F)n2)CC1,,CCOC(C)=O,O,C1CCOC1,,test
US20120225863A1,COC(=O)c1ccc2nc(-c3ccc4[nH]c(C)cc4c3)c(N(C)C(C)C)nc2c1>>Cc1cc2cc(-c3nc4ccc(C(=O)O)cc4nc3N(C)C(C)C)ccc2[nH]1,,CO,O,[Na+].[OH-],,test
US20050065099A1,C=O.Cc1cc(O)ccc1OCc1ccccc1.Cc1ccccc1>>Cc1c(OCc2ccccc2)cc(CO)c(O)c1C,,Cc1ccccc1,,COCCOC,,test
US20100056515A1,CCOc1ccc(C(CC)CC)c2c1nc(Cl)n2C.Cc1cc(Cl)cc(Cl)c1O>>CCOc1ccc(C(CC)CC)c2c1nc(Oc1c(C)cc(Cl)cc1Cl)n2C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20120108583A1,COC(=O)c1cc2nc(Nc3c(C)cccc3Cl)[nH]c2c2c1OC(C)(C)C2.Nc1cccc(C(F)(F)F)c1F>>Cc1cccc(Cl)c1Nc1nc2cc(C(=O)Nc3cccc(C(F)(F)F)c3F)c3c(c2[nH]1)CC(C)(C)O3,,Cc1ccccc1,,C[Al](C)C,,test
US20080132480A1,CC(C)OB(OC(C)C)OC(C)C.CSc1ccc(Br)cc1Cl>>CSc1ccc(B(O)O)cc1Cl,,C1CCOC1,,Cl,[Li]CCCC,test
US20050222128A1,COC(=O)c1cccc(CC(C)(C)NC(=O)OC(C)(C)C)c1>>COC(=O)c1cccc(CC(C)(C)N)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100256097A1,CC(C)c1noc(CCl)n1.O=C1NC(=O)c2ccccc21>>CC(C)c1noc(CN2C(=O)c3ccccc3C2=O)n1,,CN(C)C=O,,O,[K],test
US20150218186A1,N#Cc1ccc2c(-c3cncc4cnc(N[C@@H]5CN(C(=O)OCc6ccccc6)CC(F)(F)C5)nc34)c[nH]c2c1>>N#Cc1ccc2c(-c3cncc4cnc(N[C@@H]5CNCC(F)(F)C5)nc34)c[nH]c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150038438A1,CC1CCc2cc3c(cc2C(=O)C1)cc(CO[Si](C)(C)C(C)(C)C)n3C.COc1ccc(CN)c(OC)c1>>COc1ccc(CN=C2CC(C)CCc3cc4c(cc32)cc(CO[Si](C)(C)C(C)(C)C)n4C)c(OC)c1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,CCN(CC)CC,,test
US20140187545A1,C[Si](C)(C)C=[N+]=[N-].Cc1ccccc1Cc1c(C)nn2c(=O)cc(-c3ccncc3)[nH]c12>>Cc1ccccc1Cc1c(C)n(C)n2c(=O)cc(-c3ccncc3)nc12,,CO,ClCCl,CC(=O)O,,test
US20030225133A1,ClC(c1ccccc1)c1ccccc1.O=C1c2ccccc2C(=O)N1O>>O=C1c2ccccc2C(=O)N1OC(c1ccccc1)c1ccccc1,,CN(C)C=O,,CCN(CC)CC,O,test
US20120058997A1,Cn1ccc(=O)n(C)c1=O.Nc1[nH]ncc1-c1cccc(C(F)(F)F)c1>>O=c1ccn2ncc(-c3cccc(C(F)(F)F)c3)c2[nH]1,,CCO,,C,C[O-].[Na+],test
US20020103245A1,N#CC(=CNc1ccccc1)C(=O)c1cccc([N+](=O)[O-])c1.NNc1ccc(F)cc1>>Nc1c(C(=O)c2cccc([N+](=O)[O-])c2)cnn1-c1ccc(F)cc1,,CCO,,,,test
US20130131017A1,CC1(C)OB(O)c2cc(C=O)ccc21.CN>>CNCc1ccc2c(c1)B(O)OC2(C)C,CC(=O)O,C1CCOC1,,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04140713,NS(=O)(=O)c1cc(C(=O)CBr)ccc1N1CCCCC1.c1ccc(CNCc2ccccc2)cc1>>NS(=O)(=O)c1cc(C(O)CN(Cc2ccccc2)Cc2ccccc2)ccc1N1CCCCC1,,CCC(C)=O,,Br,,test
US20130035326A1,CC#N.COC(=O)C(C)(C)F>>CC(C)(F)C(=O)CC#N,,C1CCOC1,O,Cl,[H-].[Na+],test
US20150011546A1,Cc1[nH]c2ccccc2c1C(=O)OC(C)(C)C.O=C(Cl)c1ccccc1>>Cc1c(C(=O)OC(C)(C)C)c2ccccc2n1C(=O)c1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US05374727,OCC1=Cc2cc3ccccc3n2CC1>>OC[C@@H]1CCn2c(cc3ccccc32)C1,,Cc1ccccc1,,O=O,,test
US20050197337A1,CCCCCCCCC#N.NO>>CCCCCCCCC(=N)NO,,CCO,,CCN(CC)CC,Cl,test
US20020160996A1,COc1ccc(C(=O)Nc2c(C)c(C)c3c(c2C)C(c2ccc(C(C)C)cc2)C(C)(C)O3)cc1>>COc1ccc(CNc2c(C)c(C)c3c(c2C)C(c2ccc(C(C)C)cc2)C(C)(C)O3)cc1,,CCCCCC,,,,test
US20150191461A1,CC1(C)OB(c2cnn(C3C=CCCC3)c2)OC1(C)C.Cc1cc(Br)cc(Nc2nccc(C(F)F)n2)c1>>Cc1cc(Nc2nccc(C(F)F)n2)cc(-c2cnn(C3C=CCCC3)c2)c1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20080214654A1,COc1cc(CN(CCNC(=O)OC(C)(C)C)C(=O)c2cccs2)ccc1OCc1ccccc1.Cl>>COc1cc(CN(CCN)C(=O)c2cccs2)ccc1OCc1ccccc1.Cl,,C1COCCO1,,Cl,,test
US20080139610A1,COc1cc(Br)cc(OC)c1.O=[N+]([O-])O>>COc1cc(Br)cc(OC)c1[N+](=O)[O-],,CC(=O)OC(C)=O,,,,test
US20090137822A1,CCCCC(=O)C=CN(C)C.OC1CSC(O)CS1>>CCCCC(=O)c1ccsc1,Cl[Ti](Cl)(Cl)Cl,ClCCCl,,,,test
US20070032478A1,CC(=O)Cl.Nc1ccc(C(=O)c2ccc3c(c2)NC(=O)C3)cc1>>CC(=O)Nc1ccc(C(=O)c2ccc3c(c2)NC(=O)C3)cc1,,C1CCOC1,,,,test
US20070179151A1,COCCOc1cc2c(OC(C)C)nc(Nc3cc(C)[nH]n3)cc2cc1OCC1COC(C)(C)O1>>COCCOc1cc2c(OC(C)C)nc(Nc3cc(C)[nH]n3)cc2cc1OCC(O)CO,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20160060233A1,CC(C)c1ccccc1NC(=S)NC(=O)NC1Cc2ccc(-c3ncn(-c4ccc(OC(F)(F)F)cc4)n3)cc2C1.COC(=O)C(C)Br>>CC1S/C(=N\C(=O)NC2Cc3ccc(-c4ncn(-c5ccc(OC(F)(F)F)cc5)n4)cc3C2)N(c2ccccc2C(C)C)C1=O,,CCO,O,CC(=O)[O-].[Na+],,test
US20160002204A1,CC(C)(C)OC(=O)Nc1cc[nH]c(=O)n1.FC(CBr)CCBr>>CC(C)(C)OC(=O)Nc1ccn(CCC(F)CBr)c(=O)n1,,CS(C)=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20020040048A1,COc1ccc(S(=O)(=O)N(Cc2ccccc2)NC(=O)[C@@H]2C[C@@H](SC(c3ccccc3)(c3ccccc3)c3ccccc3)CN2S(=O)(=O)c2ccc3ccccc3c2)cc1>>COc1ccc(S(=O)(=O)N(Cc2ccccc2)NC(=O)[C@@H]2C[C@@H](S)CN2S(=O)(=O)c2ccc3ccccc3c2)cc1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20100022555A1,C1CNC1.C[C@H]1CN(S(=O)(=O)c2ccc(C(F)(F)F)cc2)CCN1C(=O)c1ccc(Cl)nc1>>C[C@H]1CN(S(=O)(=O)c2ccc(C(F)(F)F)cc2)CCN1C(=O)c1ccc(N2CCC2)nc1.Cl,,CC(C)O,,,,test
US20100179139A1,O=S(=O)(Cl)c1ccc(Br)s1.c1c[nH]cn1>>O=S(=O)(c1ccc(Br)s1)n1ccnc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US07160901B2,CC(=O)N1C(=O)Cc2cc(N)ccc21.O=S(=O)(Cl)c1ccccc1>>CC(=O)N1C(=O)Cc2cc(NS(=O)(=O)c3ccccc3)ccc21,,c1ccncc1,,O,,test
US20100069347A1,BrCc1ccccc1.O=Cc1ccc(I)cc1O>>O=Cc1ccc(I)cc1OCc1ccccc1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20100298331A1,COc1ccc(COc2cc(OCc3ccc(OC)cc3)c(C(C)C)cc2C(=O)O)cc1.Cn1ccc2cc(NCC(=O)OC(C)(C)C)ccc21>>COc1ccc(COc2cc(OCc3ccc(OC)cc3)c(C(C)C)cc2C(=O)N(CC(=O)OC(C)(C)C)c2ccc3c(ccn3C)c2)cc1,,ClCCl,,CCN=C=NCCCN(C)C,,test
US20130225561A1,CNc1cc(CCN2CCNCC2)ccc1C#N.O=CCc1ccc2c(c1)COC2=O>>CNc1cc(CCN2CCN(CCc3ccc4c(c3)COC4=O)CC2)ccc1C#N,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20080085890A1,O=C1NC(=O)c2ccc(Br)cc2C1=CNc1ccc(CN2CCCC2)cc1.OB(O)c1ccco1>>O=C1NC(=O)c2ccc(-c3ccco3)cc2C1=CNc1ccc(CN2CCCC2)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090209755A1,COC(=O)c1cnc(O)cn1.O=C(NC1=N[C@@]2(c3ccccc3F)COC[C@H]2CS1)c1ccccc1>>COC(=O)c1cnc(OCF)cn1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20150280144A1,C=C(C)c1cccnc1F.c1ccc2[nH]cnc2c1>>C=C(C)c1cccnc1-n1cnc2ccccc21,,O,,CN(C)C=O,,test
US20030225057A1,CC1CN(C(=O)C(F)(F)F)CCc2cc(F)c(Cl)cc21>>CC1CNCCc2cc(F)c(Cl)cc21,,CO,,[Na+].[OH-],,test
US20130131039A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.Cn1cc(-c2cc3nccn3c(Cl)n2)cn1>>Cn1cc(-c2cc3nccn3c(-c3cn[nH]c3)n2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20060063779A1,CO.O=C(O)c1ccc(-c2cc([N+](=O)[O-])ccc2Cl)nc1>>COC(=O)c1ccc(-c2cc([N+](=O)[O-])ccc2Cl)nc1,,CO,,C1COCCO1,Cl,test
US20120004197A1,CCOC(=O)c1ccc2c(c1)[C@@H](Oc1ccc(N3CCOCC3)cc1)C[C@H](C)N2C(C)=O>>CC(=O)N1c2ccc(C(=O)O)cc2C(Oc2ccc(N3CCOCC3)cc2)CC1C,,CCO,,Cl,[Na+].[OH-],test
US20100331293A1,Cc1c(N2CCC[C@@H]2C(=O)OC(C)(C)C)nc2cc(F)cc(F)c2c1Cl.Nc1cncc(N2CCOCC2)c1>>Cc1c(N2CCC[C@@H]2C(=O)OC(C)(C)C)nc2cc(F)cc(F)c2c1Nc1cncc(N2CCOCC2)c1,,Cc1ccccc1,,,,test
US20160031865A1,COc1ncccc1C1=C(CBr)COC1.O=Cc1c(O)cccc1O>>COc1ncccc1C1=C(COc2cccc(O)c2C=O)COC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US07465806B2,CCOC(=O)c1[nH]c(C)c(Br)c1C.O=C(CBr)Nc1ccc(Cl)cn1>>CCOC(=O)c1c(C)c(Br)c(C)n1CC(=O)Nc1ccc(Cl)cn1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120065214A1,Cc1cc(F)c(Br)cc1N.N#CCBr>>Cc1cc(F)c(Br)cc1NCC#N,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20130096134A1,C[C@H](N)c1cc2ccc(F)cc2nc1CN1CCN(C(=O)OC(C)(C)C)CC1.N#Cc1c(N)ncnc1Cl>>C[C@H](Nc1ncnc(N)c1C#N)c1cc2ccc(F)cc2nc1CN1CCN(C(=O)OC(C)(C)C)CC1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20090088431A1,CO.FC(F)(F)c1ccccc1OC1CCN(c2ccc(Cl)nn2)CC1>>COc1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1,,CO,,C[O-].[Na+],,test
US20070232645A1,C=C(C)CBr.CC(=O)Nc1ccc(Sc2ccc(O)cc2N)cc1>>CCCOc1ccc(Sc2ccc(NC(C)=O)cc2)c(N)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050075342A1,CC1(C)OC(=O)CC(=O)O1.COCC(=O)Cl>>COCC(=O)C1C(=O)OC(C)(C)OC1=O,,ClCCl,,c1ccncc1,,test
US20110144105A1,CC(C)(C)NC(=O)c1ccc(C(=CC2CCCC2)c2cc3cc(F)cnc3[nH]2)cc1>>CC(C)(C)NC(=O)c1ccc(C(CC2CCCC2)c2cc3cc(F)cnc3[nH]2)cc1,[Pd],CO,,,,test
US20030003049A1,CCCc1c(OCCCOc2cc(OCc3ccccc3)c(-c3ccc(F)cc3)cc2CC)ccc2c1OC(C(=O)NCCCOC(=O)C(C)NC(=O)OCc1ccccc1)CC2>>CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)ccc2c1OC(C(=O)NCCCOC(=O)C(C)N)CC2,[Pd],CO,ClC(Cl)Cl,,,test
US04082774,ClCCl.Oc1ccccc1O>>c1ccc2c(c1)OCO2,,CS(C)=O,,[Na+].[OH-],,test
US20110160203A1,Nc1ccccc1.O=C(O)c1cccc(Nc2ncnc3[nH]cc(C(=O)c4ccccc4)c23)c1>>O=C(Nc1ccccc1)c1ccccc1Nc1ncnc2[nH]cc(C(=O)c3ccccc3)c12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US09029392B2,OCc1cc2cccc(Cl)c2nc1-c1cccnc1>>O=Cc1cc2cccc(Cl)c2nc1-c1cccnc1,O=[Mn]=O,Clc1ccccc1,,,,test
US20120328691A1,C1CSCCN1.O=[N+]([O-])c1ccccc1F>>O=[N+]([O-])c1ccccc1N1CCSCC1,,C1COCCO1,,CCN(CC)CC,,test
US20090131461A1,CC(C)C=O.COc1cc2c(Oc3ccc(NC(=O)c4ccccc4)cc3)ccnc2cc1OCC[C@H](N)C(=O)OC1CCCC1>>COc1cc2c(Oc3ccc(NC(=O)c4ccccc4)cc3)ccnc2cc1OCC[C@H](NCC(C)C)C(=O)OC1CCCC1,CC(=O)O,CO,,[BH3-]C#N.[Na+],,test
US20080027049A1,COc1cccc(OC)c1C(=O)Cl.Nc1ccc2oc3c(c2c1)CCCCCC3>>COc1cccc(OC)c1C(=O)Nc1ccc2oc3c(c2c1)CCCCCC3,,CC(Cl)Cl,,,,test
US20100249246A1,C=C(C)B1OC(C)(C)C(C)(C)O1.CCC(C)c1cccc(Br)c1N>>CCC(C)c1cccc(C(C)C)c1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20090137590A1,COC(=O)[C@H]1C[C@@H](O)CCN1C(=O)OC(C)(C)C.c1cc(-n2cnnn2)ncc1OCc1cn[nH]n1>>COC(=O)[C@H]1C[C@H](n2ncc(COc3ccc(-n4cnnn4)nc3)n2)CCN1C(=O)OC(C)(C)C,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140023611A1,CNCCN1CCN(C(=O)OC(C)(C)C)CC1.O=C(O)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1>>CN(CCN1CCN(C(=O)OC(C)(C)C)CC1)C(=O)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1,CN(C)c1ccncc1,ClCCl,O,CCN=C=NCCCN(C)C,Cl,test
US20160137649A1,Cc1cc(CO)n(C2CCCCC2)n1>>Cc1cc(C=O)n(C2CCCCC2)n1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20060276515A1,Nc1cccnc1.O=C(Cl)CCC(c1ccccc1)c1ccccc1>>O=C(CCC(c1ccccc1)c1ccccc1)Nc1cccnc1,,ClCCl,,CCN(CC)CC,,test
US20120238105A1,Brc1cccc(-c2ccccc2)c1.C1CCOC1.CCCCCC.Clc1nc(Cl)nc(Cl)n1.[Li]CCCC>>Clc1nc(-c2cccc(-c3ccccc3)c2)nc(-c2cccc(-c3ccccc3)c2)n1,,CCCCCC,,,,test
US20100081701A1,CCN(CC)CC.COc1cccc(C(=O)Cl)c1.O=C(OCc1ccccc1)[C@@H]1CCCN1>>COc1cccc(C(=O)NN2CCC[C@H]2C(=O)OCc2ccccc2)c1,,ClCCl,,Cl,,test
US20100298356A1,COc1cc(C)c2ccsc2c1>>Cc1cc(O)cc2sccc12,,O,,Cl,c1ccncc1,test
US20100286129A1,CC1SC(=O)NN=C1c1ccc(N)c([N+](=O)[O-])c1>>CC1SC(=O)NN=C1c1ccc(N)c(N)c1,[Ni],CO,,,,test
US20070128764A1,CCCCCCCCCCc1cccs1.O=C1CCC(=O)N1Br>>CCCCCCCCCCc1ccc(Br)s1,,CN(C)C=O,,O,,test
US20070293525A1,CI.O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=S)[nH]1>>CSc1nccc(=O)[nH]1,,C1CCOC1,O,CC(=O)O,[Na+].[OH-],test
US04299821,CCCCCCCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCC(=O)N1C(=O)OCc1ccccc1>>CCCCCCCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCC(=O)N1,[Pd],CO,,,,test
US20140315888A1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2c1nc2ncc(Cl)cc2n2cnnc12>>Clc1cnc2nc(N3C[C@@H]4C[C@H]3CN4)c3nncn3c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070004736A1,CC(C)(C)OC(=O)N1CCC(/C=C\c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)CC1>>CC(C)(C)OC(=O)N1CCC(CCc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)CC1,O=[Pt],CO,,,,test
US04588732,CCOC(=O)/C=C/CP(=O)(OCC)OCC.O=CCCCCCc1cccc2cncn12>>CCOC(=O)C=CC=CCCCCCc1cccc2cncn12,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20160009744A1,CC(C)(C)[Si](C)(C)OCCCC(O)(c1ccccc1)c1csc(C2OCCO2)c1>>OCCCC(O)(c1ccccc1)c1csc(C2OCCO2)c1,,C1CCOC1,,O,,test
US20080167287A1,CCN=C=O.Nc1cccc(Cc2cnc3ncc(-c4ccc(Br)c(F)c4)nn23)c1>>CCNC(=O)Nc1cccc(Cc2cnc3ncc(-c4ccc(Br)c(F)c4)nn23)c1,,CC#N,,CCN(CC)CC,,test
US20040029874A1,CC(=O)c1ccc(NC(=O)C2CCN(C(C)C)CC2)c(C(=O)Nc2ccc(Cl)cn2)c1.NO>>CC(NO)c1ccc(NC(=O)C2CCN(C(C)C)CC2)c(C(=O)Nc2ccc(Cl)cn2)c1,,CO,,Cl,CC(=O)[O-].[Na+],test
US05585394,CC(C)(C)CC(C)(C)N.O=[N+]([O-])c1ccc(Cl)cc1[N+](=O)[O-]>>CC(C)(C)CC(C)(C)Nc1cc(Cl)ccc1[N+](=O)[O-],,CCO,,,,test
US20140329876A1,Cc1c(C2=NN3CC[C@H](O[Si](C)(C)C(C)(C)C)[C@H]3[C@@H]2OCCOC2CCCCO2)ccc(C#N)c1Cl>>Cc1c(C2=NN3CC[C@H](O[Si](C)(C)C(C)(C)C)[C@H]3[C@@H]2OCCO)ccc(C#N)c1Cl,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05665718,CCNCc1nc(-c2ncn3c2CN(C)C(=O)c2cc(F)ccc2-3)no1.Cl>>CCNCc1nc(-c2ncn3c2CN(C)C(=O)c2cc(F)ccc2-3)no1.Cl,,CCO,,,,test
US20090258883A1,CC(=O)N1CCc2ccccc21.ClC(Cl)(Cl)Cl>>Clc1ccc2c(c1)CCN2,,ClCCl,O,,,test
US20150210715A1,NO.O=Cc1ccc(Oc2ccc(Cl)cc2)cc1>>ON=Cc1ccc(Oc2ccc(Cl)cc2)cc1,,CCO,,Cl,O=C([O-])O.[Na+],test
US04334912,Cc1ccc(CCOc2ccc([N+](=O)[O-])cn2)cc1>>Cc1ccc(CCOc2ccc(N)cn2)cc1,[Pd],CCO,,[H][H],,test
US20130324547A1,CCn1cc(-c2cc(C(F)(F)F)n3nc(Br)cc3n2)c(C)n1>>Cc1nn(C)cc1C1CC(C(F)(F)F)n2nc(Br)cc2N1,,CCO,,Cl,[BH4-].[Na+],test
US20060122263A1,C=CC(c1ccccc1)c1ccccc1.O=C(OO)c1cccc(Cl)c1>>c1ccc(C(c2ccccc2)C2CO2)cc1,,ClCCl,,,,test
US04154947,CSC(=N)NN.I.NCc1cnccn1>>I.N=C(NN)NCc1cnccn1,,CCO,,,,test
US04535073,CC(=O)C(=Cc1cccc([N+](=O)[O-])c1)P(=O)(OC(C)C)OC(C)C.CCCOCCOC(=O)/C=C(/C)N>>CCCOCCOC(=O)C1=C(C)NC(C)=C(P(=O)(OC(C)C)OC(C)C)C1c1cccc([N+](=O)[O-])c1,,CC(C)O,,,,test
US05006548,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccccc1N.O=C(O)/C=C/c1cnc[nH]1>>COC(=O)c1ccccc1NC(=O)C=Cc1cn(C(=O)OC(C)(C)C)cn1,,ClCCl,,CCN(CC)CC,C[n+]1ccccc1Cl.[I-],test
US20110257151A1,COC(=O)c1ccc2c(c1)CC(C)(C)C(c1ccc(F)c([N+](=O)[O-])c1)N2.O=C(Cl)c1ccccc1>>COC(=O)c1ccc2c(c1)CC(C)(C)C(c1ccc(F)c(NC(=O)c3ccccc3)c1)N2,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100130468A1,CCOC(=O)c1cccc2c1N(C(=O)OC(C)(C)C)CC2.O=C1CCC(=O)N1Br>>CCOC(=O)c1cc(Br)cc2c1NCC2,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US04273785,CCCCCCCCCCCCCCCCBr.Nc1ccc(C(=O)c2ccccc2)cc1>>CCCCCCCCCCCCCCCCNc1ccc(C(=O)c2ccccc2)cc1,,CN(C)P(=O)(N(C)C)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20070135595A1,CC1Cc2c(Br)ccc(Br)c2C1=O>>CC1=Cc2c(Br)ccc(Br)c2C1,,C1CCOC1,CO,Cl,[BH4-].[Na+],test
US20040186102A1,CC(C)(N)C(=O)N1CCc2ccccc2C1>>CC(C)(N)CN1CCc2ccccc2C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100160302A1,CC1(C23CC4CC2CC(COCc2ccccc2)(C4)C3)OCCO1>>CC(=O)C12CC3CC1CC(COCc1ccccc1)(C3)C2,,CC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20150018547A1,COC(=O)Cc1csc2c(C)c(O)cc(C)c12.Cc1nc(C(F)(F)F)ccc1CO>>COC(=O)Cc1csc2c(C)c(OCc3ccc(C(F)(F)F)nc3C)cc(C)c12,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20120196894A1,C1=C2CCCCC2COC1.O=C(OO)c1cccc(Cl)c1>>C1CCC23OC2COCC3C1,,ClCCl,,,,test
US20080194640A1,CCn1cc(C(=O)O)cn1.O=S(Cl)Cl>>CCn1cc(C(=O)Cl)cn1,,CN(C)C=O,,Cc1ccccc1,,test
US20050192300A1,Cc1nc(N)sc1-c1ccnc(Nc2cccc([N+](=O)[O-])c2)n1.O=C(Cl)CCl>>Cc1nc(NC(=O)CCl)sc1-c1ccnc(Nc2cccc([N+](=O)[O-])c2)n1,,CN(C)C=O,,c1ccncc1,,test
US20100069381A1,COc1ccc(Nc2cc(-c3nnc(CCc4cccc(F)c4)o3)ccc2N)cc1.N#CBr>>COc1ccc(-n2c(N)nc3ccc(-c4nnc(CCc5cccc(F)c5)o4)cc32)cc1,,CCO,,O=C([O-])O.[Na+],,test
US20050037925A1,Clc1cc(Cl)c(Cl)nn1.Oc1ccccc1O>>Clc1cc2c(nn1)Oc1ccccc1O2,,C1COCCO1,,[H-].[Na+],,test
US20120108582A1,C[C@H](c1ccccc1)N1C[C@]2(C(=O)O)CC=CC[C@H]2C1=O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>C[C@H](c1ccccc1)N1C[C@]2(N)CC=CC[C@H]2C1=O,,Cc1ccccc1,,CCN(CC)CC,,test
US20150031687A1,COC(=O)[C@@H]1[C@@H](C(C)C)OCCN1S(=O)(=O)c1ccc(C)cc1>>COC(=O)[C@H]1NCCO[C@@H]1C(C)C,,CO,,[Mg],,test
US20020111367A1,CC(C)(N)CO.O=C(O)c1ccc(Cl)nc1.O=S(Cl)Cl>>CC1(C)COC(c2ccc(Cl)nc2)=N1.Cl,,CCOC(C)=O,ClCCl,O,,test
US20040023938A1,CCOS(=O)(=O)OCC.Cc1ccc(S(=O)(=O)Nc2ccc(C#N)cc2Cl)cc1>>CCN(c1ccc(C#N)cc1Cl)S(=O)(=O)c1ccc(C)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20090221555A1,CC(C)(C)[Si](C)(C)Cl.O=[N+]([O-])c1ccccc1S(=O)(=O)N1CCC(O)C1>>CC(C)(C)[Si](C)(C)OC1CCN(S(=O)(=O)c2ccccc2[N+](=O)[O-])C1,,CN(C)C=O,,c1c[nH]cn1,,test
US05789623,CC(C)[Mg]Br.Cc1ccccc1C.ClP1Oc2ccccc2-c2ccccc21>>CC(C)P(c1ccccc1-c1ccccc1O)C(C)C,,C1CCOC1,,,,test
US20110071150A1,CCOC(=O)n1c(OS(=O)(=O)C(F)(F)F)cc2cc(-c3nc(-c4ccccn4)sc3C)ccc21.OB(O)c1ccncc1F>>CCOC(=O)n1c(-c2ccncc2F)cc2cc(-c3nc(-c4ccccn4)sc3C)ccc21,,CCO,Cc1ccccc1,O=C([O-])O.[Na+],,test
US20010027196A1,CS(=O)c1nc(N)nc(-c2cccc(F)c2)c1C#N.NCc1ccccn1>>N#Cc1c(NCc2ccccn2)nc(N)nc1-c1cccc(F)c1,,COCCOC,,,,test
US20110009425A1,CC(C)(C)OC(=O)CNC(=O)c1c(O)c2c(n(Cc3ccc(Br)cc3)c1=O)CSC2>>O=C(O)CNC(=O)c1c(O)c2c(n(Cc3ccc(Br)cc3)c1=O)CSC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US04388469,C1COCCN1.ClCCCOC(CCCc1ccccc1)c1ccccc1>>c1ccc(CCCC(OCCCN2CCOCC2)c2ccccc2)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04230705,CC(C(=O)O)C(C)C(=O)c1ccccc1.NN>>CC1C(=O)NN=C(c2ccccc2)C1C,,CCO,,O,,test
US20130029987A1,CC(C)(C)OC(=O)NC1CCCCC(=O)C1>>CC(C)(C)OC(=O)NC1CCCCC(O)C1,,CO,O,[BH4-].[Na+],,test
US20060116363A1,N.O=C(O)CCSC1c2cc(OCc3ccc4cc(F)c(F)cc4n3)ccc2OCc2ncccc21>>NC(=O)CCSC1c2cc(OCc3ccc4cc(F)c(F)cc4n3)ccc2OCc2ncccc21,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US05994321,Nc1nc2c(sc(=S)n2[C@@H]2O[C@H](COC(=O)c3ccccc3)[C@@H](OC(=O)c3ccccc3)[C@@H]2F)c(=O)[nH]1>>Nc1nc2c(sc(=S)n2[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2F)c(=O)[nH]1,,CO,,CO[Na],,test
US04024255,Cc1ccc2c(=O)c(C(=O)O)cn(CCN(C)C)c2n1.Nc1nnn[nH]1>>Cc1ccc2c(=O)c(C(=O)Nc3nnn[nH]3)cn(CCN(C)C)c2n1,,CN(C)C=O,,Cl,,test
US04935509,O=C(OO)c1ccccc1Cl.O=C1CC2CCCCC2C1>>O=C1CC2CCCCC2CO1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US05725798,CCCCCCCCCCOc1ccc2cc(C(=O)O)ccc2c1>>O=C(O)C1CCc2cc(O)ccc2C1,,CC(=O)O,,Br,,test
US20110201593A1,COC(=O)N[C@H]1CC[C@H](n2nnc3cnc4c(ccn4S(=O)(=O)c4ccccc4)c32)C1>>COC(=O)N[C@H]1CC[C@H](n2nnc3cnc4[nH]ccc4c32)C1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20090203667A1,C1CSCCN1.O=C(O)/C=C/C=C(c1ccc(C(F)(F)F)cc1)c1ccc(C(F)(F)F)cc1>>O=C(/C=C/C=C(c1ccc(C(F)(F)F)cc1)c1ccc(C(F)(F)F)cc1)N1CCSCC1,,O=S(Cl)Cl,,CCN(CC)CC,O,test
US20100249119A1,CC(C)(C)OC(=O)NCc1ccc(F)c(N)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)NCc1ccc(F)c(NC(=O)C(F)(F)F)c1,,C1CCOC1,CCOC(C)=O,,,test
US20020042409A1,C=O.CC#N.NC1C2CN(C(=O)c3cc4nccc(Cl)c4s3)CC12>>CN(C)C1C2CN(C(=O)c3cc4nccc(Cl)c4s3)CC21,,CC#N,,CC(=O)O,[BH3-]C#N.[Na+],test
US20150166558A1,CCOC(=O)C1C(=O)COC12CCN(Cc1ccccc1)CC2.NCc1c(F)cccc1C(F)(F)F>>CCOC(=O)C1=C(NCc2c(F)cccc2C(F)(F)F)COC12CCN(Cc1ccccc1)CC2,,Cc1ccccc1,ClCCl,CC(=O)O,,test
US20080090856A1,C=C(C)OC(=O)Cl.CC(C)(C)c1cc(N)n(-c2ccc3ncccc3c2)n1>>C=C(C)OC(=O)Nc1cc(C(C)(C)C)nn1-c1ccc2ncccc2c1,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20040127574A1,CCOC(=O)CC(=O)c1ccnc(F)c1.FC(F)C(F)(F)Oc1cccc(CBr)c1>>CCOC(=O)C(Cc1cccc(OC(F)(F)C(F)F)c1)C(=O)c1ccnc(F)c1,,COCCOC,,O,[H-].[Na+],test
US20090075869A1,C=C[Sn](CCCC)(CCCC)CCCC.COC(=O)[C@@H]1C[C@@H](Oc2cc(-c3ccccc3)nc3ccc(Br)cc23)CN1C(=O)OC(C)(C)C>>C=Cc1ccc2nc(-c3ccccc3)cc(O[C@@H]3C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C3)c2c1,,Cc1ccccc1,,,,test
US05688795,Cc1ccc([N+](=O)[O-])c(C(=O)N(C)C)c1>>Cc1ccc(N)c(C(=O)N(C)C)c1,[Pd],CCO,,,,test
US05591762,CCCc1nc2c(Cl)cc(N3Cc4ccccc4C3=O)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCc1nc2c(Cl)cc(N3Cc4ccccc4C3=O)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110319393A1,Cc1nc(NC2CCN(C(=O)OC(C)(C)C)CC2)ccc1[N+](=O)[O-].Cl.ClCCl>>Cc1nc(NC2CCNCC2)ccc1[N+](=O)[O-].Cl.Cl,,C1COCCO1,ClCCl,O=C(O)C(F)(F)F,,test
US20100108934A1,O=S(=O)(F)C(F)(F)F.OCC(F)(F)C(F)F>>O=S(=O)(OCC(F)(F)C(F)F)C(F)(F)F,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20150057265A1,O=C1C=C(c2ccncc2[N+](=O)[O-])CC(C(F)(F)F)C1>>O=[N+]([O-])c1cnccc1C1=C[C@@H](O)C[C@@H](C(F)(F)F)C1,,CCO,CCOC(C)=O,[BH4-].[Na+],,test
US20140349993A1,CC(C)(C)OC(=O)N1CC(=O)C1.O=CC=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1CC(=CC=O)C1,,ClCCl,,,,test
US20040067955A1,CC(C)n1nc(-c2cc(C#N)c(=O)[nH]c2-c2ccccc2)ccc1=O.OCCO.[OH-]>>CC(C)n1nc(-c2cc(C(=O)O)c(=O)[nH]c2-c2ccccc2)ccc1=O,,O,,Cl,,test
US20060111445A1,CCOC(=O)CCc1ccc(OC)c(Br)c1>>COc1ccc(CCC(=O)O)cc1Br,,O,,CO,[K+].[OH-],test
US06022492,CCCCCCCCOc1ccc(-c2cnc(-c3ccc(OCc4ccccc4)c(F)c3F)nc2)cn1>>CCCCCCCCOc1ccc(-c2cnc(-c3ccc(O)c(F)c3F)nc2)cn1,,C1CCOC1,,,,test
US20100056576A1,C[C@@H]1CN(c2ccncc2[N+](=O)[O-])C[C@@H]2[C@H]1OC(=O)N2C(=O)OC(C)(C)C>>C[C@@H]1CN(c2ccncc2N)C[C@@H]2[C@H]1OC(=O)N2C(=O)OC(C)(C)C,[Pd],CO,,,,test
US20100324047A1,Cc1ccc2c(=O)[nH]ccc2c1N.Fc1ncccc1-c1ncnc2[nH]ccc12>>Cc1ccc2c(=O)[nH]ccc2c1Nc1ncccc1-c1ncnc2[nH]ccc12,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20120184508A1,CC(C)(C)OC(=O)N1CCN(CCN)CC1.CSc1nccc(-c2n[nH]c3nc(Cl)ncc23)n1>>CSc1nccc(-c2n[nH]c3nc(NCCN4CCN(C(=O)OC(C)(C)C)CC4)ncc23)n1,,CC(C)O,,CCN(CC)CC,,test
US20130131018A1,CCOC(C/N=C/c1cccc(O)c1O)OCC>>CCOC(CNCc1cccc(O)c1O)OCC,,CCO,,O,[BH4-].[Na+],test
US05215972,CC(C)(CO)C(=O)O.CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(=O)C(C)(C)CO)CC[C@]4(C)[C@H]3CC[C@]12C,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05855812,CCCCCCCOc1cnc(-c2ccc(O)cc2)nc1.FC(OC(F)(F)C(F)(F)OC(F)(F)COCCCBr)C(F)(F)F>>CCCCCCCOc1cnc(-c2ccc(OCCCOCC(F)(F)OC(F)(F)C(F)(F)OC(F)C(F)(F)F)cc2)nc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060106027A1,CN1CCNCC1.O=[N+]([O-])c1ccc(Br)cc1>>CN1CCN(c2ccc([N+](=O)[O-])cc2)CC1,,O,,,,test
US20100168418A1,CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)ccc3c(Cl)cccc32)CC1.Cl>>Cl.O=c1ccc2c(Cl)cccc2n1CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1,,C1COCCO1,,,,test
US20090156582A1,O=C(Nc1cn(C2CCCCO2)nc1C(=O)NCCC(F)(F)F)c1ccccn1>>O=C(Nc1c[nH]nc1C(=O)NCCC(F)(F)F)c1ccccn1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04471139,COC(CSC=CC(C)=O)OC>>CC(=O)C=CSCC=O,,CCOCC,,O,O=C(O)C(F)(F)F,test
US20010041802A1,COC1Oc2cccc(OC(F)F)c2-c2ccc(NC(=O)OCc3ccccc3)c(Br)c21>>COC1Oc2cccc(OC(F)F)c2-c2ccc(N)cc21,[Pd],C1CCOC1,CO,,,test
US20110257151A1,CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc([N+](=O)[O-])c1)N2>>CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(N)c1)N2,[Fe],CCO,Cl,,,test
US20150080549A1,CC(C)(C)OC(=O)N[C@H](CCCCNC(=O)C(F)(F)F)C(=O)O[C@@H]1[C@H](COP(=O)(O)O[C@H]2C[C@H](n3ccc(N)nc3=O)O[C@@H]2COP(=O)(O)O)O[C@@H](n2cnc3c(N)ncnc32)[C@@H]1O>>Nc1ccn([C@H]2C[C@H](OP(=O)(O)OC[C@@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3OC(=O)[C@H](N)CCCCNC(=O)C(F)(F)F)[C@@H](COP(=O)(O)O)O2)c(=O)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100311748A1,CCOC(=O)c1ccc(OCc2ccccn2)cc1>>O=C(O)c1ccc(OCc2ccccn2)cc1,,CCO,,[Na+].[OH-],,test
US20150368265A1,CCOC(=O)c1c(C2(O)CCCC2)oc2cc(N)c(Br)cc12>>CCOC(=O)c1c(C2=CCCC2)oc2cc(N)c(Br)cc12,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20160052888A1,NC1CCc2cc([C@H]3CC[C@]4(COC(=O)N4)C3)ccc2C1>>NC1CCc2cc([C@H]3CC[C@](N)(CO)C3)ccc2C1,,C1COCCO1,,[Na+].[OH-],,test
US20150299178A1,COC(=O)C1CCCC1=O.Clc1ccc(-c2csc(CBr)n2)cc1>>COC(=O)C1(Cc2nc(-c3ccc(Cl)cc3)cs2)CCCC1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04954600,C=CCOCCCCCCCCBr.Oc1ccc(-c2ccc(O)cc2)cc1>>C=CCOCCCCCCCCOc1ccc(-c2ccc(O)cc2)cc1,,CO,,[K+].[OH-],,test
US04590201,Cc1cc(Cl)cc(Cl)c1.O=C(Cl)c1ccc(Cl)cc1>>Cc1cc(Cl)c(C(=O)c2ccc(Cl)cc2)c(Cl)c1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20140107194A1,CCI.O=C(O)c1ccc(C[C@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@@H]2O)cc1>>CCOC(=O)c1ccc(C[C@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@@H]2O)cc1,,CN(C)C=O,Cl,O=C([O-])[O-].[K+].[K+],,test
US06204264B1,CN(C)C(=O)c1ccc(Cl)c([N+](=O)[O-])c1.CN(C)CCCN>>CN(C)CCCNc1ccc(C(=O)N(C)C)cc1[N+](=O)[O-],,CCOC(C)=O,,,,test
US20130345419A1,CC1(C)CC(C)(C)CC(O)(C(F)(F)C(=O)N2CCC[C@H]2c2cc(COS(C)(=O)=O)on2)C1.COc1cc(O)cc(OC)c1OC>>COc1cc(OCc2cc([C@@H]3CCCN3C(=O)C(F)(F)C3(O)CC(C)(C)CC(C)(C)C3)no2)cc(OC)c1OC,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20090076068A1,Cc1ccccc1CN=C=O.Cn1c(=O)[nH]c2ncccc21>>Cc1ccccc1CNC(=O)n1c(=O)n(C)c2cccnc21,,C1COCCO1,,,,test
US20140018319A1,O=S(=O)(C=C1COC1)c1ccccc1.OC1CCNCC1>>O=S(=O)(CC1(N2CCC(O)CC2)COC1)c1ccccc1,,CO,,,,test
US20160145212A1,NC(=O)CCl.Oc1ccc(-c2cc(-c3ccccc3)c3ccccc3n2)cc1>>NC(=O)COc1ccc(-c2cc(-c3ccccc3)c3ccccc3n2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130190249A1,CCOC(=O)CBr.O=C(OCc1ccccc1)[C@@H]1CNC(=O)N1C(=O)OCc1ccccc1>>CCOC(=O)CN1C[C@@H](C(=O)OCc2ccccc2)N(C(=O)OCc2ccccc2)C1=O,,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20160022626A1,O=C(O)CCOCCOCCOCCOCCOCCOCCNC(=O)CBr.O=C(Oc1c(F)c(F)c(F)c(F)c1F)C(F)(F)F>>O=C(CBr)NCCOCCOCCOCCOCCOCCOCCC(=O)Oc1c(F)c(F)c(F)c(F)c1F,,ClCCl,,c1ccncc1,,test
US20150353489A1,CCCCI.COC(=O)Cc1c[nH]c2ccc(O)cc12>>CCCCOc1ccc2[nH]cc(CC(=O)OC)c2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20120184587A1,COC(=O)c1ccc(O)c(C#N)c1.O=C1CCC(=O)N1I>>COC(=O)c1cc(I)c(O)c(C#N)c1,,CO,ClC(Cl)Cl,O=S(=O)(O)C(F)(F)F,,test
US04245088,O=C(Cc1cccs1)N[C@@H]1C(=O)N2C(C(=O)O)=C(CO)CS[C@H]12.O=C1CCC(=O)O1>>O=C(O)CCC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)Cc3cccs3)[C@H]2SC1,,ClCCl,,CCN(CC)CC,,test
US20150344466A1,BrCc1ccccc1.CCOC(=O)c1cc(CCCO)on1>>CCOC(=O)c1cc(CCCOCc2ccccc2)on1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20080175814A1,Cc1cc(Nc2ccc(NC(=O)c3ccc([N+](=O)[O-])cc3)cn2)nc(N)n1>>Cc1cc(Nc2ccc(NC(=O)c3ccc(N)cc3)cn2)nc(N)n1,[Pd],C1CCOC1,CO,,,test
US05489591,C1COCCN1.CN(C)c1nc(Cl)nc(Cl)n1>>CN(C)c1nc(Cl)nc(N2CCOCC2)n1,,CN(C)C=O,O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20070155839A1,CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(/C=C/C(=O)O)cc2)CC(C)(C)C1.N>>CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(/C=C/C(N)=O)cc2)CC(C)(C)C1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20150018363A1,CCOC(=O)c1nc(C(=O)O)cs1>>CCOC(=O)c1nc(CO)cs1,,CO,,C1CCOC1,,test
US05481034,CC1=CC(=O)CC(C)(C(F)(F)F)C1=O.OCCO>>CC1=CC2(CC(C)(C(F)(F)F)C1=O)OCCO2,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090124616A1,CCOC(=O)c1c(/C=C/CCCCN2C(=O)c3ccccc3C2=O)c2cc(F)ccc2n1CCCOc1cccc2ccccc12.CO>>O=C(O)c1ccccc1C(=O)NCCCC/C=C/c1c(C(=O)O)n(CCCOc2cccc3ccccc23)c2ccc(F)cc12,,C1CCOC1,CO,[Na+].[OH-],,test
US20100261771A1,COC(=O)Cn1nc(-c2ccc(Cl)cc2)n(CCC(F)(F)F)c1=O>>O=C(O)Cn1nc(-c2ccc(Cl)cc2)n(CCC(F)(F)F)c1=O,,CO,O,[Li+].[OH-],,test
US20160083365A1,CC(C)NS(=O)(=O)c1cccnc1.Clc1ccnc(Cl)n1>>CC(C)N(c1ccnc(Cl)n1)S(=O)(=O)c1cccnc1,,CN(C)C=O,O,[H-].[Na+],[Cl-].[NH4+],test
US20080171743A1,C1COCCN1.C[C@H]1COCCN1c1cc(CO)nc(-c2ccc(NC(=O)Nc3ccccc3)cc2)n1>>C[C@H]1COCCN1c1cc(CN2CCOCC2)nc(-c2ccc(NC(=O)Nc3ccccc3)cc2)n1,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20160068513A1,COC(=O)[C@@H]1CCCN1c1nc2c(c(Nc3cc(C(C)C)[nH]n3)n1)CCC2.Nc1cccnc1>>CC(C)c1cc(Nc2nc(N3CCC[C@H]3C(=O)Nc3cccnc3)nc3c2CCC3)n[nH]1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20050209249A1,CC(C)(C)OC(=O)N1C[C@@H](CNC(=O)c2cccc(C(=O)NS(C)(=O)=O)c2)C[C@H]1C(=O)N1CCSC1>>CS(=O)(=O)NC(=O)c1cccc(C(=O)NC[C@@H]2CN[C@H](C(=O)N3CCSC3)C2)c1,,CO,,C1COCCO1,Cl,test
US20060100229A1,CCCCn1nc(C(=O)OCC)cc1CC(C)(C)O.N>>CCCCn1nc(C(N)=O)cc1CC(C)(C)O,,CO,,,,test
US05977110,N=C(NC(=O)OCc1ccccc1)N(C(=O)OCc1ccccc1)C1CCC(CCN2CCN(c3ccccc3)CC2)CC1>>N=C(N)NC1CCC(CCN2CCN(c3ccccc3)CC2)CC1,[Pd],CO,,[H][H],,test
US04565568,CC(Oc1ccc(O)cc1)C(=O)O.Fc1cc(Br)cnc1F>>CC(Oc1ccc(Oc2ncc(Br)cc2F)cc1)C(=O)O,,CS(C)=O,O,Cl,[Na+].[OH-],test
US20100004245A1,Clc1cnc(Cl)cn1.OC1CCNCC1>>OC1CCN(c2cnc(Cl)cn2)CC1,,CC(C)O,,,,test
US04080335,CN(C)CCOc1ccc2c(c1)OC(C)(C)C=C2c1cccc(C(F)(F)F)c1.Cl>>CN(C)CCOc1ccc2c(c1)OC(C)(C)CC2c1cccc(C(F)(F)F)c1.Cl,[Pd],CCO,,[H][H],,test
US20130237571A1,CON=C(COc1ccc(CO)cc1)c1ccccc1.N#CC(CC(=O)OCc1ccccc1)c1ccc(O)cc1>>CO/N=C(\COc1ccc(COc2ccc(C(C#N)CC(=O)OCc3ccccc3)cc2)cc1)c1ccccc1,,Cc1ccccc1,,CCCCP(CCCC)CCCC,,test
US20070093501A1,COC(=O)C(O)c1ccccc1.O=C=Nc1ccc(Cl)cc1>>COC(=O)C(OC(=O)Nc1ccc(Cl)cc1)c1ccccc1,,C1CCOC1,,CCN(CC)CC,,test
US20090143372A1,CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4ccc(CO)s4)cc23)CC1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4ccc(C=O)s4)cc23)CC1,O=[Mn]=O,C1CCOC1,,,,test
US20060241115A1,COc1cc2[nH]cc(I)c(=O)c2cc1OC.O=P(Cl)(Cl)Cl>>COc1cc2ncc(I)c(Cl)c2cc1OC,,CN(C)C=O,,,,test
US20120058999A1,CCOC(=O)C1=NCCn2c(C)ccc21>>Cc1ccc2n1CCNC2CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150361078A1,CNC(=O)c1ccc(C#N)c(C)c1.O=CO>>CNC(=O)c1ccc(C=O)c(C)c1,[Ni],,,,,test
US20060004052A1,CC(C)(C)OC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)Nc1cc2c3c(c[nH]c3c1)C=NNC2=O.Cl>>Cl.N[C@H](Cc1ccc2ccccc2c1)C(=O)Nc1cc2c3c(c[nH]c3c1)C=NNC2=O,,C1COCCO1,,,,test
US20080139631A1,N#Cc1ccc2c(ccn2CC(=N)NO)c1C(F)(F)F.O=C(Cl)c1cc(C(F)(F)F)ccc1Cl>>N#Cc1ccc2c(ccn2Cc2noc(-c3cc(C(F)(F)F)ccc3Cl)n2)c1C(F)(F)F,,CC#N,,CCN(CC)CC,,test
US06300352B1,C[C@H](Oc1ccc(-c2ccccc2)cc1)C(O)C#Cc1cccnc1>>C[C@H](Oc1ccc(-c2ccccc2)cc1)C(O)CCc1cccnc1,[Pd],CCOC(C)=O,,,,test
US04925944,CCOC(=O)/C=C(/C)Nc1ccccc1.CN(C)C=O>>CCOC(=O)c1cc2ccccc2nc1C,,CCOC(C)=O,ClCCl,O=P(Cl)(Cl)Cl,,test
US20060009511A9,FCCBr.O=Cc1cccc(O)c1>>O=Cc1cccc(OCCF)c1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04863958,C=CCc1ccc2oc(C(=O)c3ccc(OC)cc3)c(C)c2c1O>>CCCc1ccc2oc(Cc3ccc(OC)cc3)c(C)c2c1O,[Pd],CCO,,,,test
US04475944,COc1cc(OC)nc(N)n1.O=C=NS(=O)(=O)Oc1ccccc1-c1nnco1>>COc1cc(OC)nc(NC(=O)NS(=O)(=O)Oc2ccccc2-c2nnco2)n1,,C1CCOC1,,,,test
US05977116,C=CCC(F)(F)C(=O)NN1CCN(C(=O)OC(C)(C)C)CC1>>C=CCC(F)(F)C(=O)NN1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160130299A1,CCCN(C(=O)[C@@H](NC(=O)[C@@H](C(C)C)N(C)C(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(C)C)cc1)[C@@H](C)CC)[C@H](C[C@@H](OC(=O)NC)c1nc(C(=O)N[C@@H](Cc2ccccc2)CC(C)(C)C(=O)O)cs1)C(C)C>>CCCN(C(=O)[C@@H](NC(=O)[C@@H](C(C)C)N(C)C(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](N)C(C)C)cc1)[C@@H](C)CC)[C@H](C[C@@H](OC(=O)NC)c1nc(C(=O)N[C@@H](Cc2ccccc2)CC(C)(C)C(=O)O)cs1)C(C)C,,CN(C)C=O,,C1CCNCC1,,test
US20150368249A1,BrCc1ccc(Br)nc1.CSc1nc2nccc(O)n2n1>>CSc1nc2n(Cc3ccc(Br)nc3)ccc(=O)n2n1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US04927822,NN.O=C(O)CSC(=S)c1ccc(C(F)(F)F)cc1>>NNC(=S)c1ccc(C(F)(F)F)cc1,,CO,O,CC(=O)O,[K+].[OH-],test
US04003904,CC(=O)OC(C)=O.c1ccc(C(CCN2CC3CCC2CC3)(c2cccnc2)c2nnn[nH]2)cc1>>Cc1nnc(C(CCN2CC3CCC2CC3)(c2ccccc2)c2cccnc2)o1,,c1ccncc1,,,,test
US04812461,O=C(c1ccc(F)cc1)C1CCNCC1.O=C1C2CCCCC2C(=O)N1CCC1CO1>>O=C(c1ccc(F)cc1)C1CCN(CC(O)CCN2C(=O)C3CCCCC3C2=O)CC1,,CCCCO,,,,test
US20120202776A1,Clc1nnc(Cl)c(Cl)n1.Fc1cc(S)cc(C(F)(F)F)c1>>Fc1cc(Sc2nc(Cl)nnc2Cl)cc(C(F)(F)F)c1,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20120232112A1,CCOC(=O)c1cc(NCC(=O)C(C)(C)C)n(-c2ccccc2)n1>>CC(C)(C)C(=O)CNc1cc(C(=O)O)nn1-c1ccccc1,,CCO,,[Na+].[OH-],,test
US20090143361A1,BrB(Br)Br.COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)cc(Cl)c4)n3c2n1>>Cc1nc(Br)n2c1c(C)nc1ccc(=O)[nH]c12,,CC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US20150210688A1,C[Si](C)(C)CCOCCl.N#Cc1c[nH]nc1I>>C[Si](C)(C)CCOCn1cc(C#N)c(I)n1,,C1CCOC1,,[H-].[Na+],,test
US20140303127A1,N#Cc1ccc(COC2CCCCO2)cc1.NO>>NC(=NO)c1ccc(COC2CCCCO2)cc1,,CCO,,CCN(CC)CC,Cl,test
US05516774,Cc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3-c3ccccc32)cc1.O=C1CCC(=O)N1Cl>>Cc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3ccc(Cl)n3-c3ccccc32)cc1,,C1CCOC1,,,,test
US20110034507A1,COC(=O)c1cccc(-c2ccc3cc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)ccc3c2)n1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2cc(-c3cccc(C(=O)O)n3)ccc2c1,,C1CCOC1,CO,[Na+].[OH-],,test
US20060009427A1,C1CCC2OC2C1.N#Cc1ccc(F)cc1C(F)(F)F.O=C([O-])[O-]>>N#Cc1ccc(OC2CCCCC2O)cc1C(F)(F)F,,CN(C)C=O,,O,,test
US20110009378A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Clc1ccc(C2(C3NCCc4c3[nH]c3ccccc43)CCC2)cc1>>CC(C)(C)OC(=O)N1CCc2c([nH]c3ccccc23)C1C1(c2ccc(Cl)cc2)CCC1,,C1CCOC1,,CCN(CC)CC,,test
US08906135B1,CCCc1cn(C[Si](C)(C)C)n[n+]1C.O=S(=O)([N-]S(=O)(=O)C(F)(F)F)C(F)(F)F>>CCCc1cn(C[Si](C)(C)C)n[n+]1C.O=S(=O)([N-]S(=O)(=O)C(F)(F)F)C(F)(F)F,,CC#N,,[I-].[Li+],,test
US20140024650A1,Fc1ccc(Br)nc1.OB(O)c1ccc(O)cc1>>Oc1ccc(-c2ccc(F)cn2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20130165446A1,CCOC(=O)c1c(C(C)Sc2ccc(Oc3ccc([N+](=O)[O-])c(N(C)C(=O)OC(C)(C)C)c3)cc2)ncn1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCOC(=O)c1c(C(C)Sc2ccc(Oc3ccc(N)c(N(C)C(=O)OC(C)(C)C)c3)cc2)ncn1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1,[Pd],C1CCOC1,,CO,[H][H],test
US20070293516A1,CC(C)n1nc(I)c2c(N)ncnc21.OB(O)c1ccc(O)c(F)c1>>CC(C)n1nc(-c2ccc(O)c(F)c2)c2c(N)ncnc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US20100256127A1,NN1CCOCC1.O=C(O)c1ccc(OCc2c(-c3ccccn3)noc2CO)nc1>>O=C(NN1CCOCC1)c1ccc(OCc2c(-c3ccccn3)noc2CO)nc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US04011238,CC(CO)N1C(=O)N(c2ccc(Cl)cc2)CC1C.O=S(Cl)Cl>>CC(CCl)N1C(=O)N(c2ccc(Cl)cc2)CC1C,,ClC(Cl)Cl,,,,test
US20070249659A1,CCOP(=O)(Cc1ccc(C(=O)O)cc1)OCC.O=Cc1nccs1>>O=C(O)c1ccc(/C=C/c2nccs2)cc1,,O,,C1CCOC1,CC(C)(C)[O-].[K+],test
US20020002161A1,OCCc1c2n(c3ccccc13)CCN(Cc1ccccc1)CC2.Oc1ccccc1>>c1ccc(CN2CCc3c(CCOc4ccccc4)c4ccccc4n3CC2)cc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110230458A1,COCO[C@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1C(=O)OC>>COCO[C@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1CO,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20020165264A1,CCOc1c(OCC)c(=O)c1=O.Nc1ccc(Cl)nc1>>CCOc1c(Nc2ccc(Cl)nc2)c(=O)c1=O,,CCO,,,,test
US20100204265A1,CC(C)(C)OC(=O)N1CC=C(c2ccccc2F)CC1.OO>>CC(C)(C)OC(=O)N1CCC(c2ccccc2F)C(O)C1,,C1CCOC1,,O,[Na+].[OH-],test
US05854265,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.N#Cc1ccc(Cn2cncc2CC(N)=O)cc1>>N#Cc1ccc(Cn2cncc2CC(N)=S)cc1,,C1COCCO1,,,,test
US20100016164A1,CC1(C)COC(=S)N(Cc2ccccc2NS(=O)(=O)C(F)(F)F)C1.COC(=O)Cl>>COC(=O)N(c1ccccc1CN1CC(C)(C)COC1=S)S(=O)(=O)C(F)(F)F,,CC#N,,O,O=C([O-])O.[Na+],test
US20110294781A1,Cc1cc2nc(NN)cc(N3CCOCC3)n2n1.O=Cc1c[nH]c2ccccc12>>Cc1cc2nc(NN=Cc3c[nH]c4ccccc34)cc(N3CCOCC3)n2n1,,CCO,,CC(=O)O,,test
US20060258740A1,CC(C)N(NC(=O)c1ccccc1)C(=O)CCc1ccccc1Br.O=[N+]([O-])c1cccc(B(O)O)c1>>CC(C)N(NC(=O)c1ccccc1)C(=O)CCc1ccccc1-c1cccc([N+](=O)[O-])c1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US04675316,N#CC(Cl)Sc1ccc(Cl)cc1.c1c[nH]cn1>>N#CC(Sc1ccc(Cl)cc1)n1ccnc1,,O,,,,test
US20120270838A1,C=CCCOC(=O)c1cc(OCCC=C)cc(C(F)(F)F)c1>>C=CCCOc1cc(C(=O)O)cc(C(F)(F)F)c1,,CO,,Cl,[Na+].[OH-],test
US04234598,CN(SC(Cl)(Cl)Cl)C(=O)Cl.Oc1cccc2c1OC=CCO2>>CN(SC(Cl)(Cl)Cl)C(=O)Oc1cccc2c1OCCCO2,,c1ccccc1,,,,test
US05696276,C1CCOC1.COc1ccc(OC)c2c(OC)c(C=O)cc(OC)c12>>CCCCC(O)c1cc(OC)c2c(OC)ccc(OC)c2c1OC,,C1CCOC1,,[Cl-].[NH4+],,test
US08748627B2,CC(=O)C#N.CC(C)Oc1ccc(Oc2ncc(-c3nsc(=O)o3)s2)cc1>>CC(=O)c1nc(-c2cnc(Oc3ccc(OC(C)C)cc3)s2)ns1,,Cc1ccccc1C,,,,test
US20130225588A1,COC(=O)Cc1cc2ccc(F)cc2c(-c2ccc(S(=O)(=O)c3ccccc3Cl)cc2)c1C>>Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2ccccc2Cl)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20030139475A1,Cl.NC(=O)Nc1cc(C(O)CNCCOc2ccc3c(c2)[nH]c2ccccc23)ccc1OCc1ccccc1>>Cl.NC(=O)Nc1cc(C(O)CNCCOc2ccc3c(c2)[nH]c2ccccc23)ccc1O,[Pd],CO,,ClC(Cl)Cl,,test
US04293695,CCOc1ccc([N+](=O)[O-])nc1C>>CCOc1ccc(N)nc1C,[Pd],CCO,,,,test
US20080021028A1,C=CCBr.CC(C)OC(=O)C[C@H](O)C(=O)OC(C)C>>C=CC[C@@H](C(=O)OC(C)C)[C@H](O)C(=O)OC(C)C,,C1CCOC1,,,,test
US05610174,COc1cccc2c1CC1NC(=O)COC1C2>>COc1cccc2c1CC1NCCOC1C2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20030119842A1,CC(=O)Cl.Nc1ccccn1.O=Cc1ccccn1.[C-]#[N+]C1CCCCC1>>CC(=O)[n+]1c(-c2ccccn2)c(NC2CCCCC2)n2ccccc21.[Cl-],,[O-][Cl+3]([O-])([O-])O,,,,test
US20020156105A1,C[Si](C)(C)CCOCCl.OC1(c2nccs2)CCCCC1>>C[Si](C)(C)CCOCOC1(c2nccs2)CCCCC1,,ClCCl,,CCN(C(C)C)C(C)C,[Cl-].[NH4+],test
US20090143353A1,Cc1c(C=O)c(N2CC[C@H](N(C)C)C2)c2oc(C3CC3)nc2c1C#N>>Cc1c(CO)c(N2CC[C@H](N(C)C)C2)c2oc(C3CC3)nc2c1C#N,,CO,ClCCl,[BH4-].[Na+],,test
US20090093483A1,CC(C)(C)OC(=O)CNC(=O)C1=C(O)C(C)(C)c2c(ccc(OCc3ccccc3)c2F)C1=O>>CC1(C)C(=O)C(C(=O)NCC(=O)O)=C(O)c2ccc(OCc3ccccc3)c(F)c21,,O=C(O)C(F)(F)F,,,,test
US20130029971A1,Nc1cccnc1N1CCC(CCN2CCCCC2)CC1.O=C(Cl)c1cccc(Cl)c1>>O=C(Nc1cccnc1N1CCC(CCN2CCCCC2)CC1)c1cccc(Cl)c1,,CN(C)C=O,,,,test
US20060287522A1,Brc1ncccn1.O=C(O)c1ccc(B(O)O)cc1>>O=C(O)c1ccc(-c2ncccn2)cc1,,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20060148801A1,CCOC(=O)C(Cl)C(C)=O.COc1ccnc(N)c1>>CCOC(=O)c1c(C)nc2cc(OC)ccn12,,CCO,,,,test
US20160083376A1,CCOC(=O)C(C)C(=O)OCC.N#CCC#N>>CCOC(=O)C(C)C(=O)C(C#N)C#N,,C1CCOC1,CCOC(C)=O,C1CCC2=NCCCN2CC1,,test
US20090196912A1,COc1cc(C(=O)Nc2cncc(-c3cccc(O)c3)c2)ccc1C>>COc1cc(CNc2cncc(-c3cccc(O)c3)c2)ccc1C,,C1CCOC1,,,,test
US06002008,COc1cc2ncc(C#N)c(Nc3ccc(Cl)cc3F)c2cc1OC>>N#Cc1cnc2cc(O)c(O)cc2c1Nc1ccc(Cl)cc1F,,[NH4+],[OH-],Cl,c1ccncc1,test
US04985557,CCOC(=O)c1cn2c3c(c(F)c(F)cc3c1=O)OCC2CO.O=C(Cl)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>CCOC(=O)c1cn2c3c(c(F)c(F)cc3c1=O)OCC2COC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1,,C1CCOC1,,c1ccncc1,,test
US05250504,Cc1c(C(=O)O)cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl.NS(N)(=O)=O>>Cc1c(C#N)cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl,,O=S1(=O)CCCC1,,O=S(Cl)Cl,,test
US20150257385A1,CC(C)(C)OC(=O)NCCc1ccc(Oc2c(Cl)cc([N+](=O)[O-])cc2Cl)cc1>>NCCc1ccc(Oc2c(Cl)cc([N+](=O)[O-])cc2Cl)cc1,,CCOC(C)=O,,O=C(O)C(F)(F)F,,test
US20150353539A1,CC(=O)c1cc2cc(C=Cc3cc([N+](=O)[O-])ccc3C)cnc2[nH]1>>CC(=O)c1cc2cc(CCc3cc(N)ccc3C)cnc2[nH]1,[Pd],CN(C)C=O,,[H][H],,test
US04474963,C=CCc1ccc(OCC2CO2)c(OC)c1.O>>C=CCc1ccc(OCC(O)CO)c(OC)c1,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US04339386,COc1ccc(-c2ccc(C=O)o2)cc1OC.NO>>COc1ccc(-c2ccc(C=NO)o2)cc1OC,,O,,Cl,CC(=O)[O-].[Na+],test
US20040127574A1,O=C(O)C(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccccc1F.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>O=C1NC(Cc2ccc(C(F)(F)F)cc2)C(c2ccccc2F)O1,,C1CCOC1,,CCN(CC)CC,O,test
US20140275049A1,CC(C)Oc1cc(B2OC(C)(C)C(C)(C)O2)cc(C(C)(C)C)c1.COC(=O)c1ccc(-c2cc(I)n(-c3ccc(C(N)=O)cc3)n2)cc1>>COC(=O)c1ccc(-c2cc(-c3cc(OC(C)C)cc(C(C)(C)C)c3)n(-c3ccc(C(N)=O)cc3)n2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20100216779A1,C=CS(C)(=O)=O.COc1cc(N2CCCN(C(=O)[O-])C(C(C)(C)C)C2)c(C)cc1[N+](=O)[O-]>>COc1cc(N2CCCN(CCS(C)(=O)=O)CC2)c(C)cc1[N+](=O)[O-],,C1COCCO1,ClCCl,O=C(O)C(F)(F)F,,test
US20080234237A1,CN1CCC(N2C(=O)CCc3cc([N+](=O)[O-])ccc32)CC1>>CN1CCC(N2C(=O)CCc3cc(N)ccc32)CC1,[Pd],CCO,,[H][H],,test
US20090054392A1,FC(F)(F)CN[C@H]1CCN(c2nccc(-c3ccc4ccccc4c3)n2)C1>>N[C@H]1CCN(c2nccc(-c3ccc4ccccc4c3)n2)C1,,C1CCOC1,,B,,test
US20070037816A1,CCOC(=O)[C@@H]1CC[C@H](C#N)N1C(=O)OC(C)(C)C.[N-]=[N+]=[N-].[NH4+]>>CCOC(=O)[C@@H]1CC[C@H](c2nn[nH]n2)N1C(=O)OC(C)(C)C,,CN(C)C=O,,[Cl-].[Na+],,test
US20040143007A1,BrCC1CCC1.N#CC(C#N)Cc1ccc(SC(F)(F)F)cc1>>N#CC(C#N)(Cc1ccc(SC(F)(F)F)cc1)CC1CCC1,,CN(C)C=O,,[H-].[Na+],,test
US06166006,Cc1ccc(-c2cccc(/C=C/C(=O)Nc3ccc(-c4cccnc4)cc3)c2)cc1.O=C(OO)c1cccc(Cl)c1>>Cc1ccc(-c2cccc(/C=C/C(=O)Nc3ccc(-c4ccc[n+]([O-])c4)cc3)c2)cc1,,C1CCOC1,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20070149542A1,C=CCBr.O=C(c1cccc(C2CCNCC2)c1F)C(F)(F)F>>C=CCN1CCC(c2cccc(C(=O)C(F)(F)F)c2F)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20050288346A1,CCCC(=O)Cl.Cc1c(O)cccc1O>>CCCC(=O)c1ccc(O)c(C)c1O,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120082702A1,CCOC(=O)CCCBr.NC(=O)c1ccc(N2CCC[C@@H](N)C2)nc1Nc1ccc(C(=O)N2CCOCC2)cc1>>NC(=O)c1ccc(N2CCC[C@@H](N3CCCC3=O)C2)nc1Nc1ccc(C(=O)N2CCOCC2)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030219880A1,CCOC(=O)[C@@H](C)[C@H](C)OC1CCCCO1>>C[C@H](CO)[C@H](C)OC1CCCCO1,,C1CCOC1,Cc1ccccc1,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20120184542A1,COc1ncc2cc(C(=O)Nc3cc(C(=O)O)ccc3Cl)c(=O)[nH]c2n1.Clc1ccccc1CBr>>COc1ncc2cc(C(=O)Nc3cc(C(=O)OCc4ccccc4Cl)ccc3Cl)c(=O)[nH]c2n1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20030225057A1,COc1ccc2c(c1)CCN(C(=O)C(F)(F)F)CC2C.O=C1CCC(=O)N1Cl>>COc1cc2c(cc1Cl)C(C)CN(C(=O)C(F)(F)F)CC2,,CC#N,O,,,test
US04873234,COCOc1cccc(ON=C(C)C)c1C#N>>Nc1noc2cccc(O)c12,,CO,,,,test
US20100137313A1,COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)cnc1OC.Cc1cc(C)cc(Nc2ncc(Br)c(-n3nc(C(F)(F)F)cc3C)n2)c1>>COC(=O)c1cc(-c2cnc(Nc3cc(C)cc(C)c3)nc2-n2nc(C(F)(F)F)cc2C)cnc1OC,,CC#N,O,ClCCl,O=C([O-])[O-].[Na+].[Na+],test
US20060211720A1,CCOc1cc(O[Si](C)(C)C(C)(C)C)c(F)c(C(Nc2ccc3c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc3c2)c2nc(-c3ccccc3)cn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1>>CCOc1cc(O)c(F)c(C(Nc2ccc3c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc3c2)c2nc(-c3ccccc3)cn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150011546A1,COC(=O)c1c(Br)[nH]c2ccccc12.OB(O)c1ccccc1>>COC(=O)c1c(-c2ccccc2)[nH]c2ccccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120022041A1,Fc1nc(F)nc(F)n1.O=C(O)c1noc(-c2ccccn2)c1C(F)(F)F>>O=C(F)c1noc(-c2ccccn2)c1C(F)(F)F,,ClCCl,,c1ccncc1,,test
US05965745,COc1cc(C(=O)O)ccc1Cc1c[nH]c2ccc(C(=O)NCC(C)CC(F)(F)F)cc12.OCc1ccccc1>>COc1cc(C(=O)OCc2ccccc2)ccc1Cc1c[nH]c2ccc(C(=O)NCC(C)CC(F)(F)F)cc12,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030220341A1,O=Cc1cc2ccccc2[nH]1.c1cnc2c(c1)CCCC2NC1CCC(NCc2nc3ccccc3[nH]2)CC1>>c1cnc2c(c1)CCCC2N(Cc1cc2ccccc2[nH]1)C1CCC(NCc2nc3ccccc3[nH]2)CC1,,CO,,[BH4-].[Na+],,test
US20060138453A1,C1CCOC1.Cc1ccccc1.[Li]C(C)(C)C.c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)ccnc23)cc1>>Cc1cccc(-c2cc(-c3ccccc3)c3ccc4c(-c5ccccc5)cc(-c5cccc(C)c5)nc4c3n2)c1,,C1CCOC1,Cc1ccccc1,O,,test
US04999381,CC(C)C(=O)Cl.Nc1ccc(C(=O)O)c(Cl)c1>>CC(C)C(=O)Nc1ccc(C(=O)O)c(Cl)c1,,COCCOC,O,Cl,O=C([O-])O.[Na+],test
US20140323468A1,C[C@H](O)c1c(F)cncc1-c1cnc2c(c1)CCCN2C(N)=O>>CC(=O)c1c(F)cncc1-c1cnc2c(c1)CCCN2C(N)=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20080045554A1,CCCCCn1/c(=N/N=C/CCC(=O)O)[nH]c(=O)c2[nH]cnc21>>CCCCCn1c2nc[nH]c2c(=O)n2c(CCC(=O)O)nnc12,,CC(=O)O,,,,test
US20130158072A1,COc1ccc2c(c1)CN(C(=O)OC(C)(C)C)[C@@](C)(C(=O)O)C2>>COc1ccc2c(c1)CN(C)[C@@](C)(C(=O)O)C2,,C1CCOC1,Cl,CCN(CC)CC,,test
US04014920,CC(=O)NC(=Cc1ccc(OC(C)=O)cc1)C(=O)O>>CC(=O)NC=Cc1ccc(OC(C)=O)cc1,[Cu],c1ccc2ncccc2c1,,O=C=O,,test
US05534529,CSc1cccc(COCCCOS(C)(=O)=O)c1NC(=O)CC1c2ccccc2Oc2ccccc21.c1c[nH]cn1>>CSc1cccc(COCCCn2ccnc2)c1NC(=O)CC1c2ccccc2Oc2ccccc21,,CCOC(C)=O,CN(C)C=O,,,test
US04380643,CCc1ccc2nn(-c3cc(C)ccc3OC(C)=O)nc2c1>>CCc1ccc2nn(-c3cc(C)ccc3O)nc2c1,,CCO,,Cl,[Na+].[OH-],test
US20100184739A1,CC(C)(C)c1cc(C(C)(C)C)c(NC(=O)c2c[nH]c3c(Br)ccc([N+](=O)[O-])c3c2=O)cc1O>>CC(C)(C)c1cc(C(C)(C)C)c(NC(=O)c2c[nH]c3cccc(N)c3c2=O)cc1O,[Pd],CCOC(C)=O,,Cl,,test
US20110098320A1,CCOC(=O)CBr.C[C@@H](c1ccc(Br)cc1)N(CCC(=O)c1ccc(F)cc1)C(=O)OC(C)(C)C>>CCOC(=O)CC(O)(CCN(C(=O)OC(C)(C)C)[C@@H](C)c1ccc(Br)cc1)c1ccc(F)cc1,[Zn],C1CCOC1,,II,,test
US20020198200A1,COC(=O)C(SC1CCCC1)c1ccc(Cl)c(Cl)c1>>O=C(O)C(SC1CCCC1)c1ccc(Cl)c(Cl)c1,,CCO,O,[K+].[OH-],,test
US04743602,CC(C)(C)c1ccc(C2CC2C(=O)O)o1.O=C(Cl)C(=O)Cl>>CC(C)(C)c1ccc(C2CC2C(=O)Cl)o1,,CCCCCC,,,,test
US20100029687A1,COC(=O)c1cccc(O)c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>COC(=O)c1cccc(OC(=O)Oc2ccc([N+](=O)[O-])cc2)c1,,CCN(CC)CC,,Cc1ccccc1,,test
US05011849,COC(=O)c1cccc(OCc2cccc(Cl)c2)c1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COC(=S)c1cccc(OCc2cccc(Cl)c2)c1,,Cc1ccccc1C,,,,test
US20110218192A1,CC(=O)c1cc(Br)ccc1O.CC1CCC(=O)CC1>>CC1CCC2(CC1)CC(=O)c1cc(Br)ccc1O2,,CO,,C1CCNC1,,test
US04685958,CSC(=NC#N)SC.NS(=O)(=O)c1cc(Cl)ccc1Cl>>CSC(=NC#N)NS(=O)(=O)c1cc(Cl)ccc1Cl,,CCO,O,Cl,[Na+].[OH-],test
US20130172384A1,Cn1nc(-c2ccc(Br)cc2)n(C[C@@H]2CCN(C(=O)C3CC3)C2)c1=O.OB(O)c1ccc(F)cc1>>Cn1nc(-c2ccc(-c3ccc(F)cc3)cc2)n(C[C@@H]2CCN(C(=O)C3CC3)C2)c1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20060004197A1,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1cc(F)c([N+](=O)[O-])cc1N>>Cc1ccc(S(=O)(=O)Nc2cc([N+](=O)[O-])c(F)cc2N)cc1,,c1ccncc1,,Cl,,test
US20140315889A1,C=C1CCc2c(c3ccccc3n2Cc2ccc(C(=O)OC)cc2)C1=O.FC1(F)CNC1>>COC(=O)c1ccc(Cn2c3c(c4ccccc42)C(=O)C(CN2CC(F)(F)C2)CC3)cc1,,Cc1ccccc1,,Cl,O=C([O-])[O-].[K+].[K+],test
US04028356,NNC1=Nc2ccc(Cl)cc2C(c2c(F)cccc2F)=NC1.O=C(CCl)CCCCO>>OCCCCC(CCl)=NNC1=Nc2ccc(Cl)cc2C(c2c(F)cccc2F)=NC1,,C1CCOC1,,,,test
US04435401,Clc1nc(Cl)nc(Cl)n1.O=CN1CCNCC1>>O=CN1CCN(c2nc(Cl)nc(Cl)n2)CC1,,CC(C)=O,,O=C([O-])O.[Na+],,test
US20110275656A1,COC(=O)c1cc(N)c([N+](=O)[O-])cn1>>COC(=O)c1cc(N)c(N)cn1,[Pd],C1CCOC1,,,,test
US20110028493A1,CCOC(=O)c1cnn(CC(=O)O)c1.O=C(Cl)C(=O)Cl>>CCOC(=O)c1cnn(CC(=O)Cl)c1,CN(C)C=O,ClCCl,,,,test
US20130225638A1,CS(=O)(=O)c1ccc(-n2cncc2-c2ccccc2)nc1.O=C1CCC(=O)N1Cl>>CS(=O)(=O)c1ccc(-n2cnc(Cl)c2-c2ccccc2)nc1,CC(C)(C#N)N=NC(C)(C)C#N,ClC(Cl)(Cl)Cl,,,,test
US05288748,CCCN(C(=O)CC)C1COc2ccc(N)cc2C1>>CCCN(CCC)C1COc2ccc(N)cc2C1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060189650A1,CC(C)OC(=O)CC(c1cc(F)cc(F)c1)C1CCN(C(=O)OCc2ccccc2)CC1.CS(=O)(=O)Cl>>CC(C)OC(=O)CC(c1cc(F)cc(F)c1)C1CCN(S(C)(=O)=O)CC1,,ClCCl,,CCN(CC)CC,,test
US05939439,Cc1ccc(-n2cc(Cl)ccc2=O)nc1.O=C1CCC(=O)N1Cl>>Cc1ccc(-n2cc(Cl)cc(Cl)c2=O)nc1,,CC#N,,,,test
US04154941,CC(C)=O.O=S(=O)(OCC(F)(F)F)C(F)(F)F.O=[N+]([O-])c1ccc(O)c(O)c1>>O=[N+]([O-])c1ccc(OCC(F)(F)F)c(OCC(F)(F)F)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160168156A1,COc1ncc(F)cc1C#CCCN1C(=O)c2ccccc2C1=O>>COc1ncc(F)cc1C#CCCN,,CO,ClCCl,NN,,test
US20110224247A1,COC(=O)c1cnccc1C>>Cc1ccncc1C(=O)O,,C1COCCO1,,[Na+].[OH-],,test
US20160176882A1,CC1CCCN1.Fc1ccc(Br)cn1>>CC1CCCN1c1ccc(Br)cn1,,CO,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20120064181A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(-c2cc(C(=O)O)cc(NCc3ccccc3)n2)cc1>>Cc1ccc(-c2cc(C(=O)OC(C)(C)C)cc(NCc3ccccc3)n2)cc1,,C1CCOC1,,CN(C)c1ccccn1,,test
US20130022587A1,CCOC(=O)/C(=C/c1cn([C@H]2CC[C@@H](O)CC2)cn1)CCCNC(=O)OC(C)(C)C.Oc1ccncc1>>CCOC(=O)/C(=C/c1cn([C@@H]2CC[C@@H](Oc3ccncc3)CC2)cn1)CCCNC(=O)OC(C)(C)C,,C1CCOC1,Cc1ccccc1,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050288273A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCC(Br)C3=O)C(=O)O1.NNC(=S)NCc1ccccc1>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCc2c(NCc4ccccc4)n[nH]c2-3)C(=O)O1,,CCO,,Cl,,test
US20060069088A1,CC(C)(C)OC(=O)N1CCC(c2ccc3onc(O)c3c2)CC1.Cc1ccccc1S(=O)(=O)Cl>>Cc1ccc(S(=O)(=O)Oc2noc3ccc(C4CCN(C(=O)OC(C)(C)C)CC4)cc23)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20080188502A1,NCC(F)(F)F.O=S(=O)(Cl)c1ccc(Br)cn1>>O=S(=O)(NCC(F)(F)F)c1ccc(Br)cn1,,ClCCl,,O=C([O-])O.[Na+],,test
US06002008,CN(C)c1ccc(Nc2c(C#N)cnc3ccc([N+](=O)[O-])cc23)cc1>>CN(C)c1ccc(Nc2c(C#N)cnc3ccc(N)cc23)cc1,[Pd],,,NN,,test
US20140296225A1,CC(C)(C)OC(=O)N1CCN(C2CCc3cc(C#N)ccc3C2)C(=O)C1>>N#Cc1ccc2c(c1)CCC(N1CCNCC1=O)C2,,C1COCCO1,,Cl,,test
US20150239873A1,CS(=O)(=O)Cl.OCC(CN1CCOC(c2cccc(C(F)(F)F)c2)C1)C(F)(F)F>>CS(=O)(=O)OCC(CN1CCOC(c2cccc(C(F)(F)F)c2)C1)C(F)(F)F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120270875A1,Cc1nc(NCCCc2cccc3[nH]ncc23)nc(C)c1C(=O)N[C@@H](CNC(=O)c1cccs1)C(=O)O.ClCCCN1CCOCC1>>Cc1nc(NCCCc2cccc3[nH]ncc23)nc(C)c1C(=O)N[C@@H](CNC(=O)c1cccs1)C(=O)OCCCN1CCOCC1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,[I-].[Na+],test
US20100311798A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H](N)CCc1ccc(Cl)cc1>>COC(=O)[C@H](CCc1ccc(Cl)cc1)NC(=O)OC(C)(C)C,,CC#N,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20030083443A1,CC1CO1.CNc1ccc(C)cc1>>Cc1ccc(N(C)CC(C)O)cc1,,CO,,,,test
US20110092703A1,CC(C)c1ccc(N2CCN(Cc3ccccc3)CC2CO)cc1.CS(=O)(=O)Cl>>CC(C)c1ccc(N2CCN(Cc3ccccc3)CC2COS(C)(=O)=O)cc1,,c1ccncc1,,O,,test
US20100305102A1,C1CNCCN1.Clc1cc(Cl)c(Cl)nn1>>Clc1cc(N2CCNCC2)c(Cl)nn1,,CCO,,,,test
US20070129379A1,CCN(CC)CC.Fc1cc(Br)c(CBr)cc1Br>>NCc1cc(Br)c(F)cc1Br,,ClCCl,,CO,,test
US20080188528A1,Br.Cc1cc(C)cc(C(O)c2cc(C)cc(C)c2)c1>>Cc1cc(C)cc(C(Br)c2cc(C)cc(C)c2)c1,,CC(=O)O,,,,test
US20120252828A1,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.O=c1c2cc(Cc3ccc(Cl)nc3)c3cnccc3c2ncn1[C@H]1CCCC[C@@H]1O>>Cn1cc(-c2ccc(Cc3cc4c(=O)n([C@H]5CCCC[C@@H]5O)cnc4c4ccncc34)cn2)cn1,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,C1CCOC1,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140135518A1,COC(=O)c1ccc(OC(F)(F)C(F)OC(F)(F)C(F)(OC(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F)cc1>>O=C(O)c1ccc(OC(F)(F)C(F)OC(F)(F)C(F)(OC(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F)cc1,,O,,Cl,[K+].[OH-],test
US20030149001A1,CC(C)(C)OC(=O)N1CCN(c2ccc(N)nc2)CC1.CCc1cc2cnc(S(C)=O)nc2n(C2CCCC2)c1=O>>CCc1cc2cnc(Nc3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)cn3)nc2n(C2CCCC2)c1=O,,Cc1ccccc1,,,,test
US20030225142A1,CCCCC/C=C/CCCBr.CN1CCC[C@H]1c1cccnc1>>CCCCC/C=C/CCC[n+]1cccc([C@@H]2CCCN2C)c1.[Br-],,CC(=O)O,,,,test
US20050277652A1,CN1CCC(N2CCN(C(=O)Nc3cc(Oc4ccc(N)cc4)ccn3)CC2)CC1.O=C(Cc1ccccc1)N=C=S>>CN1CCC(N2CCN(C(=O)Nc3cc(Oc4ccc(NC(=S)NC(=O)Cc5ccccc5)cc4)ccn3)CC2)CC1,,CCO,Cc1ccccc1,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US05122523,CC1(C)OC(C(O)CNCCO)[C@H](CC2CCCCC2)N1C(=O)OCc1ccccc1>>N[C@@H](CC1CCCCC1)C(O)C(O)CNCCO,[Pd],CCO,,,,test
US05371088,N#CC1(c2ccccc2)CCC(=O)CC1.c1ccc(CN2CCNCC2)cc1>>N#CC1(c2ccccc2)CCC(N2CCN(Cc3ccccc3)CC2)CC1,,CCO,O,CC(=O)O,[BH3-]C#N.[Na+],test
US05405865,CCOC(=O)CC(C)=O.O=C(CBr)C(F)(F)F>>CCOC(=O)C1=C(C)OCC1(O)C(F)(F)F,,CCO,Cc1ccccc1,[H-].[Na+],,test
US20110183985A1,CC(=O)c1cc(Cl)c2cccnc2c1N1CCNCC1.Cc1noc(C)c1C(=O)Cl>>CC(=O)c1cc(Cl)c2cccnc2c1N1CCN(C(=O)c2c(C)noc2C)CC1,,ClCCl,ClCCl,CCN(CC)CC,,test
US20160002175A1,NCC1CC1.Nc1nc(Cl)cc(Cl)n1>>Nc1nc(Cl)cc(NCC2CC2)n1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20160221994A1,CCOC(=O)CC(=O)OCC.ClCc1cccnc1>>CCOC(=O)C(Cc1cccnc1)C(=O)OCC,,CCO,,Cl,[Na],test
US20110172442A1,COC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)C=Cc1ccccc1F>>CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)C=Cc1ccccc1F)C(=O)O,,CO,,[Na+].[OH-],,test
US04041048,CC1NOCCc2ccccc21.CN=C=O>>CNC(=O)N1OCCc2ccccc2C1C,,CCOCC,,,,test
US20090029988A1,COCCc1nc2c(N)nc3ccccc3c2n1CCCNS(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)NCCCn2c(CCO)nc3c(N)nc4ccccc4c32)cc1,,CC#N,ClCCl,BrB(Br)Br,,test
US20050222408A1,COc1ccc(C=O)c(OC)c1.O=C(c1ccc([N+](=O)[O-])o1)N1CCNCC1>>COc1ccc(CN2CCN(C(=O)c3ccc([N+](=O)[O-])o3)CC2)c(OC)c1,,C1CCOC1,,CC(=O)O,,test
US20040029874A1,O=C(Nc1ccc(Cl)cn1)c1ccccc1[N+](=O)[O-]>>Nc1ccccc1C(=O)Nc1ccc(Cl)cn1,[Ni],C1CCOC1,CCOC(C)=O,,,test
US06121182,Cc1ccc(C(C)C)c2c1C(=O)C(C)C2>>Cc1ccc(C(C)C)c2c1C(O)C(C)C2,,CCOCC,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20090286807A1,CC[C@@H]1C[C@@H](C2C[N@@]2S(=O)(=O)c2ccccc2[N+](=O)[O-])OC1=O.Cc1ccccc1N1CC(C)(C)NCC1=O>>CC[C@@H]1C[C@@H]([C@H](CN2CC(=O)N(c3ccccc3C)CC2(C)C)NS(=O)(=O)c2ccccc2[N+](=O)[O-])OC1=O,,Cc1ccccc1,,,,test
US04588722,CSC(=NC#N)SC.NCCN1CCC(Nc2nc3cccnc3n2Cc2ccc(F)cc2)CC1>>CSC(=NC#N)NCCN1CCC(Nc2nc3cccnc3n2Cc2ccc(F)cc2)CC1,,CO,,,,test
US20130018034A1,NC1(C(F)(F)F)CC1.O=C(O)c1ccc(Br)cn1>>O=C(NC1(C(F)(F)F)CC1)c1ccc(Br)cn1,,ClCCl,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20160168139A1,CON(C)C(=O)c1cc(COC(C)=O)ncn1>>CON(C)C(=O)c1cc(CO)ncn1,,CO,,C[O-].[Na+],,test
US20080045556A1,N#Cc1ccc(C(=O)CBr)cc1.NC=O>>N#Cc1ccc(-c2cocn2)cc1,,O,,,,test
US04963590,N#CCC(N)=O.O=Cc1cc(O)c(O)c([N+](=O)[O-])c1>>N#CC(=Cc1cc(O)c(O)c([N+](=O)[O-])c1)C(N)=O,,CCO,,C1CCNCC1,CC(=O)O,test
US20090239854A1,CC1CCN(CCBr)C1C.CN1CCC(=O)CC1.NNc1ccc(Cl)cc1>>CC1CCN(CCn2c3c(c4cc(Cl)ccc42)CN(C)CC3)C1C,,CCN(CC)CC,,Cl,,test
US05910498,CC(C)[C@H](N)C(=O)N[C@H]1CCN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3-c2cc(N)c(F)cc2F)C1.CS(=O)(=O)O>>CC(C)[C@H](N)C(=O)N[C@H]1CCN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3-c2cc(N)c(F)cc2F)C1.CS(=O)(=O)O,,CCO,,,,test
US05393788,COc1ccc(C=C[N+](=O)[O-])cc1OC1CCCC1>>COc1ccc(CCN)cc1OC1CCCC1,,C1CCOC1,CCOCC,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100069629A1,CN(C)CCO.Nc1ccnc(Cl)c1>>CN(C)CCOc1cc(N)ccn1,,Cc1ccccc1,,[H-].[Na+],,test
US20120015950A1,O=C1c2ccccc2C(=O)N1CCC1CCN(c2ccc(-c3ccc(F)cc3)cn2)CC1>>NCCC1CCN(c2ccc(-c3ccc(F)cc3)cn2)CC1,,CCO,,NN,O,test
US20130157977A1,BrCCOCCBr.Cc1c(Cn2c(C)nc3c(Br)cc(N)cc32)cccc1C(F)(F)F>>Cc1c(Cn2c(C)nc3c(Br)cc(N4CCOCC4)cc32)cccc1C(F)(F)F,,O,OCCO,CCN(C(C)C)C(C)C,,test
US20150119380A1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1c(O)cc(F)cc1F>>CC(C)(C)OC(=O)N1CCN(c2cc(O)c(C=O)c(F)c2)CC1,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US20110046122A1,CC1(c2cccc(N)c2)COCC(=O)N1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC1(c2cccc(N)c2)COCC(=S)N1,,COCCOC,,,,test
US20100004222A1,CC(=O)N1CCCc2ccc([N+](=O)[O-])cc21>>CC(=O)N1CCCc2ccc(N)cc21,[Pd],CO,,,,test
US20160002221A1,CC(C)(O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.CO>>COC(C)(C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1,,CO,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20020035127A1,COC(=O)[C@@H](N)Cc1ccc(OCc2c(Cl)cccc2Cl)cc1.O=C(O)c1cccnc1S>>COC(=O)[C@H](Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)NC(=O)c1cccnc1S,,CN(C)C=O,,CN1CCOCC1,Cl,test
US20070043066A1,COC(=O)CCC(CO)NC(=O)c1ccc(-c2ccccc2)cc1>>O=C(O)CCC(CO)NC(=O)c1ccc(-c2ccccc2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20100121048A1,COC(=O)c1ncn(C2CCc3ccccc3C2)c1-c1ccccc1>>O=C(O)c1ncn(C2CCc3ccccc3C2)c1-c1ccccc1,,C1CCOC1,CO,[Na+].[OH-],,test
US04475944,O=C=NS(=O)(=O)Cl.Oc1ccccc1-c1ccon1>>O=C=NS(=O)(=O)Oc1ccccc1-c1ccon1,,Cc1ccccc1,,,,test
US20060111375A1,CC(=O)c1ccc(B(O)O)cc1.COc1cc2nccc(Oc3ccc(C)nc3I)c2cc1OC>>COc1cc2nccc(Oc3ccc(C)nc3-c3ccc(C(C)=O)cc3)c2cc1OC,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100075965A1,CC(=O)Nc1cn2cc(-c3cnc(N)c(OC4CCN(C(=O)OC(C)(C)C)CC4)n3)ccc2n1>>CC(=O)Nc1cn2cc(-c3cnc(N)c(OC4CCNCC4)n3)ccc2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100105659A1,CC(=O)OC(C)=O.Cc1ncccc1Oc1cc(Sc2ccccn2)cnc1Nc1nc(C2CC3CCC(C2)N3)ns1.Cl>>CC(=O)N1C2CCC1CC(c1nsc(Nc3ncc(Sc4ccccn4)cc3Oc3cccnc3C)n1)C2.Cl,,ClCCl,,CCN(CC)CC,,test
US20130217680A1,COC(=O)c1cccc2c(CN3CCN(C(=O)OC(C)(C)C)CC3)coc12>>COC(=O)c1cccc2c1OCC2CN1CCN(C(=O)OC(C)(C)C)CC1,[Pd],CC(=O)O,,O=C([O-])[O-].[Na+].[Na+],,test
US04812573,CCOC(=O)CCN1CCc2ccc(S(=O)(=O)Nc3cccc(Cl)c3)cc2C1>>O=C(O)CCN1CCc2ccc(S(=O)(=O)Nc3cccc(Cl)c3)cc2C1,,CCO,,[Na+].[OH-],,test
US20160229872A1,CCOC(=O)c1[nH]nc(Br)c1N.COc1ccc(B(O)O)cc1>>CCOC(=O)c1[nH]nc(-c2ccc(OC)cc2)c1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20120208817A1,CCOc1cc(C=O)cc([N+](=O)[O-])c1O.NC(N)=O.O=C(Cc1ccccc1)c1ccc(Br)cc1>>CCOc1cc(C2NC(=O)NC(c3ccc(Br)cc3)=C2c2ccccc2)cc([N+](=O)[O-])c1O,,CCO,,Cl,,test
US20050176796A1,COc1ccc(-n2nc(C(N)=O)c3c2-c2cn[nH]c2CC3)cc1>>COc1ccc(-n2nc(C(N)=O)c3ccc4[nH]ncc4c32)cc1,,C1COCCO1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20130190307A1,CC(=O)O[C@@H](C)C(=O)N1CCC(n2nnc3cnc4ccc(Cl)nc4c32)CC1>>C[C@H](O)C(=O)N1CCC(n2nnc3cnc4ccc(Cl)nc4c32)CC1,,C1CCOC1,CO,[Li+].[OH-],,test
US04579865,O=C(O)C(=O)Cc1cccc(OCc2ccccc2)c1[N+](=O)[O-]>>Oc1cccc2cc[nH]c12,[Pd],CC(=O)O,,,,test
US20100305093A1,CC(=O)c1ccc(C(=O)N2CCOc3ccc(-c4ccc5cn[nH]c5c4)cc3C2)cc1.CI>>CC(=O)c1ccc(C(=O)N2CCOc3ccc(-c4ccc5cnn(C)c5c4)cc3C2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080161317A1,CCOC(=O)C(=O)c1ccccc1.Nc1ccc(Cl)nc1N>>Oc1nc2ccc(Cl)nc2nc1-c1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20110263571A1,Cc1ccc(N2CCCN(C(=O)OC(C)(C)C)CC2)c(C)c1.Cl>>Cc1ccc(N2CCCNCC2)c(C)c1.Cl,,ClC(Cl)Cl,,CCOC(C)=O,,test
US20150284362A1,O=C1C(C2C=CCCC2)CCCN1Cc1ccccc1>>O=C1C(C2CCCCC2)CCCN1Cc1ccccc1,[Pd],CCO,,,,test
US20120220622A1,COC(=O)CBr.C[C@@H](N)c1ccc(Br)cc1>>COC(=O)CN[C@H](C)c1ccc(Br)cc1,,ClCCl,,CCN(CC)CC,,test
US20070049581A1,CC(C)(C)OC(=O)N1CCN(C2(C)CCN(Cc3ccccc3)CC2)CC1>>CC(C)(C)OC(=O)N1CCN(C2(C)CCNCC2)CC1,[Pd],CO,,Cl,[H][H],test
US20130310362A1,Brc1ncnc(Br)c1-c1ccccc1.N>>Nc1ncnc(Br)c1-c1ccccc1,,CCO,CO,,,test
US20150018422A1,CCOC(=O)CC(c1cccc(CNc2ccc(-c3cc(OC)ccc3F)c(CC(C)(C)C)c2)c1)C1CC1>>COc1ccc(F)c(-c2ccc(NCc3cccc(C(CC(=O)O)C4CC4)c3)cc2CC(C)(C)C)c1,,CCO,,Cl,[Na+].[OH-],test
US20120122817A1,CCOC(=O)C(=CN(C)C)C(=O)c1cc(Br)ncc1F.COCC(N)COC>>CCOC(=O)c1cn(C(COC)COC)c2cnc(Br)cc2c1=O,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US05849920,COc1nc(F)c(C(F)(F)F)cc1Cl.N>>COc1nc(N)c(C(F)(F)F)cc1Cl,,CCO,,,,test
US20110136802A1,CC(C)(C)OC(=O)N1CCNCC1.CC1(C)CCC[C@@]2(C)[C@H]1CC[C@@]1(C)c3c(C(=O)O)cc(O)cc3S(=O)(=O)C[C@@H]12>>CC(C)(C)OC(=O)N1CCN(C(=O)c2cc(O)cc3c2[C@]2(C)CC[C@H]4C(C)(C)CCC[C@]4(C)[C@H]2CS3(=O)=O)CC1,,C1CCOC1,CN(C)C=O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090137541A1,O=C1CCc2ccccc21.O=Cc1cccc(OCCCCl)c1>>O=C1C(=Cc2cccc(OCCCCl)c2)Cc2ccccc21,,CO,,[Na+].[OH-],,test
US20130116243A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)NC(=O)CO4)cc2)CCC1.CI>>CN1C(=O)COc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)cc21,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20100280243A1,CC(C)(C)OC(=O)N1[C@@H](CCCC(=O)O)COC[C@H]1c1cc(F)c(F)c(F)c1.Cl>>Cl.O=C(O)CCC[C@H]1COC[C@@H](c2cc(F)c(F)c(F)c2)N1,,COCCOC,,,,test
US20120202853A1,COC(=O)c1oc(C)c(-c2c(-c3ccc(OC)cc3)nn(C)c2C=O)c1C>>Cc1oc(C(=O)O)c(C)c1-c1c(-c2ccc(O)cc2)nn(C)c1C=O,,ClCCl,,BrB(Br)Br,,test
US20060014768A1,CSc1nc(=O)n(C)c2c1c(=O)n(-c1ccccc1)c(=O)n2-c1ccccc1.Nc1ccc(Cl)cc1>>Cn1c(=O)nc(Nc2ccc(Cl)cc2)c2c(=O)n(-c3ccccc3)c(=O)n(-c3ccccc3)c21,,CCOCC,,Cc1ccccc1,,test
US04119726,CCCCCCC(C)(O)CC(=O)OCC>>CCCCCCC(C)(O)CC(=O)O,,CCO,,[K+].[OH-],,test
US20090247746A1,Nc1c(C#Cc2nccs2)cccc1C(=O)OCc1ccccc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(OCc1ccccc1)c1cccc(C#Cc2nccs2)c1NC(=O)C(F)(F)F,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20080032955A1,CC1(C)[C@H](C(=O)O)CC[C@]1(C)C(=O)O>>CC1(CO)CCC(CO)C1(C)C,,C1CCOC1,CCOCC,,,test
US20100249118A1,CC(C)[Si](C(C)C)(C(C)C)n1cc(C(=O)c2c(F)ccc(N)c2F)c2cc(-c3cccnc3)cnc21.CCN(CC)CC.CS(=O)(=O)Cl>>CCS(=O)(=O)Nc1ccc(F)c(C(=O)c2cn([Si](C(C)C)(C(C)C)C(C)C)c3ncc(-c4cccnc4)cc23)c1F,,ClCCl,,O,,test
US20050222177A1,CN.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-n1c(=O)c2cnc(S(C)=O)nc2n(C)c1=O>>CNc1ncc2c(=O)n(-c3cc(NC(=O)c4cccc(C(F)(F)F)c4)ccc3C)c(=O)n(C)c2n1,,C1CCOC1,,,,test
US20080004302A1,COc1cc(C)cc(COc2cc(Nc3ccnc(Cl)n3)[nH]n2)c1.Cc1cc(CN)on1>>COc1cc(C)cc(COc2cc(Nc3ccnc(NCc4cc(C)no4)n3)n[nH]2)c1,,CCO,,CCN(C(C)C)C(C)C,Cl,test
US20150366197A1,COc1cc(O)c(Cl)cc1C(=O)c1[nH]c(Cl)c(Cl)c1-n1c(C(=O)c2cc(Cl)c(O)cc2OC)cc(Cl)c1Cl>>O=C(c1cc(Cl)c(O)cc1O)c1[nH]c(Cl)c(Cl)c1-n1c(C(=O)c2cc(Cl)c(O)cc2O)cc(Cl)c1Cl,,ClCCl,,BrB(Br)Br,,test
US04180394,CC(C)O.CCOC(=O)CN(CP(=O)(OCl)OCl)C(=O)C(F)(F)F.Sc1ccccc1>>CCOC(=O)CN(C(=O)C(F)(F)F)C(OC(C)C)P(=O)(O)OSc1ccccc1,,CCOCC,,CCN(CC)CC,,test
US20020111513A1,C1CCOC1.CC(CO)(C(=O)O)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1.CCOC(=O)C(C)(CO)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1.CO>>CCCCC(CO)(C(=O)OC)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US06306818B1,C#CC(=O)OCC.C=CCCCCCCCCO>>C=CCCCCCCCCO/C=C/C(=O)OCC,,CCOCC,,CN1CCOCC1,,test
US20100249099A1,COc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)c2ncn(C3CCNCC3)c2n1.CS(=O)(=O)Cl>>COc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)c2ncn(C3CCN(S(C)(=O)=O)CC3)c2n1,,ClCCl,,O,O=C([O-])[O-].[K+].[K+],test
US20050272036A1,C=O.CC(C)NC(C)C.O=C(c1ccccc1)C(O)c1ccccc1>>CC(C)N(CC(O)(C(=O)c1ccccc1)c1ccccc1)C(C)C,,CCO,,,,test
US05750526,CCOP(=O)(OCC)C1CCc2c([N+](=O)[O-])c(C(F)(F)F)cc3[nH]c(=O)c(=O)n1c23>>CCOP(=O)(OCC)C1CCc2c(N)c(C(F)(F)F)cc3[nH]c(=O)c(=O)n1c23,[Pd],CCO,,,,test
US20100137381A1,N#Cc1cc(Br)ccc1N.OB(O)c1ccc(Cl)cc1>>N#Cc1cc(-c2ccc(Cl)cc2)ccc1N,,O,,COCCOC,O=C([O-])[O-].[K+].[K+],test
US05623073,O=C(Cn1c(NCCO)nc2ccccc21)c1ccccc1.O=S(Cl)Cl>>Cl.O=C(Cn1c(NCCCl)nc2ccccc21)c1ccccc1,,ClC(Cl)Cl,,,,test
US20140275172A1,CN(C)C=O.Cc1oc2c(Br)cc(F)cc2c1C>>Cc1oc2c(C=O)cc(F)cc2c1C,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20110059957A1,CC(C)(C)OC(=O)NN.CCS(=O)(=O)Nc1nc(CCc2ccc(CC(=O)O)cc2)cs1>>CCS(=O)(=O)Nc1nc(CCc2ccc(CC(=O)NNC(=O)OC(C)(C)C)cc2)cs1,,C1CCOC1,,O,O=C(n1ccnc1)n1ccnc1,test
US20100273779A1,CCOC(=O)CC(C)(C)C(=O)c1ccc(OCc2ccccc2)cc1>>CCOC(=O)CC(C)(C)C(=O)c1ccc(O)cc1,[Pd],CO,,,,test
US04795751,CN1CCN(c2c(F)c(F)c3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1.NCc1ccccc1>>CN1CCN(c2c(F)c(NCc3ccccc3)c3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1,,c1ccncc1,,,,test
US20140323468A1,CCOC(=O)Cc1cncc(-c2cnc3c(c2)CCCN3C(N)=O)c1>>NC(=O)N1CCCc2cc(-c3cncc(CC(=O)O)c3)cnc21,,CCO,O,[Li+].[OH-],,test
US04684640,C=CCSC1CC(=O)N1C(C(=S)OCc1ccc([N+](=O)[O-])cc1)=C(Oc1ccc(Cl)cc1)C(=O)C(C)(C)C.ClCl>>CC(C)(C)C(=O)C(Oc1ccc(Cl)cc1)=C(C(=S)OCc1ccc([N+](=O)[O-])cc1)N1C(=O)CC1Cl,,ClC(Cl)(Cl)Cl,ClCCl,,,test
US20160068559A1,CC(C)(C)OC(=O)N(CCCN)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21.CC(C)(C)c1ccc2[nH]c(Cl)nc2c1>>CC(C)(C)OC(=O)N(CCCNc1nc2cc(C(C)(C)C)ccc2[nH]1)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21,,CCCCO,,,,test
US20070105891A1,Cc1nc(C(N)=O)c(Br)s1>>Cc1nc(C#N)c(Br)s1,,ClCCl,,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US05591855,C=Cc1ccccn1.O=C1NCc2c3c(c4[nH]c5ccccc5c4c21)Cc1ccc(Br)cc1-3>>O=C1NCc2c3c(c4[nH]c5ccccc5c4c21)Cc1ccc(C=Cc2ccccn2)cc1-3,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,CCN(CC)CC,,test
US04564610,C1CCCCCC(N2CCCCCCCCCN2)CCCC1.C=CCBr.CCO.CCOC(=O)c1ncc2[nH]c3ccc(N)cc3c2n1>>C=CCN(CC=C)c1ccc2[nH]c3cnc(C(=O)OCC)nc3c2c1,,CCO,,,,test
US20100069391A1,CNc1nc(Cl)nc(Cl)n1.N[C@H]1CC[C@@H](C(=O)O)CC1>>CNc1nc(Cl)nc(N[C@H]2CC[C@@H](C(=O)O)CC2)n1,,CC#N,O,[Na+].[OH-],,test
US20120178765A1,CI.Cc1ccccc1COc1cc(/C=C/c2ccc(F)cc2)cc(C(=O)O)c1>>COC(=O)c1cc(/C=C/c2ccc(F)cc2)cc(OCc2ccccc2C)c1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20130303515A1,CC(=O)Cl.CC(C)(C)OC(=O)NCCN>>CC(=O)NCCNC(=O)OC(C)(C)C,,ClCCl,,,,test
US20150274750A1,CCN(C(C)C)C(C)C.Clc1ccnc2c1CCCN2.O=[N+]([O-])c1ccc(S(=O)(=O)NCC(c2ccc(C(F)(F)F)cc2)C2CCNCC2)cc1>>O=[N+]([O-])c1ccc(S(=O)(=O)NCC(c2ccc(C(F)(F)F)cc2)C2CCN(c3ncnc4c3CCCN4)CC2)cc1,,CN1CCCC1=O,,,,test
US20110118230A1,CCc1c(C#N)ncc2[nH]c3ncccc3c12.O=C1CCC(=O)N1Br>>CCc1c(C#N)ncc2[nH]c3ncc(Br)cc3c12,,CCOC(C)=O,CN(C)C=O,,,test
US05045228,CCCCCCCCCCCCOc1ccc(OC(=O)c2ccc(OC(C)=O)cc2)cc1Cl>>CCCCCCCCCCCCOc1ccc(OC(=O)c2ccc(O)cc2)cc1Cl,,C1CCOC1,CO,[Li+].[OH-],,test
US05888941,COC(=O)C(Cl)C(C)=O.NC(=S)c1ccccc1>>COC(=O)c1sc(-c2ccccc2)nc1C,,CCO,,,,test
US04487783,Fc1ccc(CNC2CCCC2)cc1.S=C=Nc1ccccc1>>Fc1ccc(CN(C(=S)Nc2ccccc2)C2CCCC2)cc1,,Cc1ccccc1,,,,test
US05041573,CCOC(=O)CBr.N[C@@H](c1ccccc1)[C@H](O)c1ccccc1>>CCOC(=O)CN[C@@H](c1ccccc1)[C@H](O)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US06245761B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)NCCCCO>>CC(C)N(CCCCO)C(=O)OC(C)(C)C,,C1COCCO1,,O,[Na+].[OH-],test
US20160221945A1,CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)O.NCc1cc(-c2cnc(C(F)(F)F)nc2)c(Cl)cn1>>CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)NCc1cc(-c2cnc(C(F)(F)F)nc2)c(Cl)cn1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030105323A1,CCCCC(C(C)=O)C(=O)OCC.N=C(N)N>>CCCCc1c(C)nc(N)nc1O,,CCO,,O=C(O)O,,test
US20100152455A1,OB(O)c1ccc(Br)cc1.Oc1ccc(Br)cc1-c1nc2ccccc2s1>>Oc1ccc(-c2ccc(Br)cc2)cc1-c1nc2ccccc2s1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[K+].[K+],test
US20070280928A1,CC1(O)CC(c2nc(I)c3c(Cl)nccn23)C1.N>>CC1(O)CC(c2nc(I)c3c(N)nccn23)C1,,C1CCOC1,CC(C)O,,,test
US04210749,COc1cccc(CC(C)N)c1.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1cccc(CC(C)NS(=O)(=O)c2ccc(C)cc2)c1,,c1ccccc1,,CCN(CC)CC,,test
US20020147344A1,CCOC(=O)N1CCC(c2cn(CC3CC3)c3ccccc23)CC1>>c1ccc2c(c1)c(C1CCNCC1)cn2CC1CC1,,CC(C)O,,[K+].[OH-],,test
US20100292276A1,Nc1cc(Br)ccc1NC(=O)C=CC1CCC2(CC1)OCCO2>>O=C1CCC(C=Cc2nc3cc(Br)ccc3[nH]2)CC1,,C1COCCO1,,Cl,O=C([O-])O.[Na+],test
US20080306060A1,BrBr.O=C1CC(=O)CC2(CCCCC2)C1>>O=C1CC2(CCCCC2)CC(=O)C1Br,,CC(=O)O,,,,test
US20110137068A1,COC(=O)c1cccc(N)c1F.O=C(Cl)c1ccccc1>>COC(=O)c1cccc(NC(=O)c2ccccc2)c1F,,ClCCl,,Cl,c1ccncc1,test
US20080039444A1,CCOC(CCCc1ccc(OCCCN2CCCCCC2)cc1)OCC.CO>>COC(CCCc1ccc(OCCCN2CCCCCC2)cc1)OC,,CO,,,,test
US20100160255A1,CCOC(=O)C1CCN(c2cc(C(=O)N3CCC(N4CCCC5(C4)CC(C)(C)OC5=O)CC3)c3ccccc3n2)CC1>>COC(=O)C1CCN(c2cc(C(=O)N3CCC(N4CCCC5(C4)CC(C)(C)OC5=O)CC3)c3ccccc3n2)CC1,,CO,,[Na+].[OH-],,test
US04096146,CCC1CN2CCC1CC2[C@@H](O)c1ccnc2ccc(OC)cc12>>CC[C@H]1CN2CC[C@H]1C[C@H]2[C@H](O)c1ccnc2ccc(OC)cc12,,CO,,c1ccccc1,,test
US20140024650A1,CCOC(=O)[C@@H]1COCC[C@@H]1N[C@@H](C)c1ccccc1>>CCOC(=O)[C@@H]1COCC[C@@H]1N,[Pd],CCO,,,,test
US20140350019A1,COC=O.Fc1ccc(Br)cc1>>O=Cc1cc(Br)ccc1F,,C1CCOC1,O,CC(C)NC(C)C,[Li]CCCC,test
US05972975,CC(=O)OC(C)=O.Cc1cc(N)nc(CCCCN)c1>>CC(=O)NCCCCc1cc(C)cc(N)n1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20130216498A1,CCS(=O)(=O)N1CCC(C)C(N(C)C(=O)OC(C)(C)C)C1>>CCS(=O)(=O)N1CCC(C)C(NC)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04630896,BrC(Br)(Br)Br.CCCCC[C@@H]1CC[C@@H](CCO)CC1>>CCCCC[C@@H]1CC[C@@H](CCBr)CC1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070037974A1,CCOC(=O)CC(=O)c1ccccc1F.CNN>>Cn1nc(-c2ccccc2F)cc1O,,CCO,,,,test
US20100137317A1,C#CC(C)(C)O[Si](C)(C)C.CON(C)C(=O)c1ccncc1>>CC(C)(C#CC(=O)c1ccncc1)O[Si](C)(C)C,,C1CCOC1,,[Li]CCCC,,test
US05547983,COC(=O)c1ccc(/C=C(/C)c2ccc(OC)c(C34CC5CC(CC(C5)C3)C4)c2)cc1>>COc1ccc(/C(C)=C/c2ccc(C(=O)O)cc2)cc1C12CC3CC(CC(C3)C1)C2,,CO,,[Na+].[OH-],,test
US20160039772A1,CCI.Cn1c(=O)n(CCCO)c(=O)c2c(Cc3ccc(Cl)cc3)c(O)ccc21>>CCOc1ccc2c(c1Cc1ccc(Cl)cc1)c(=O)n(CCCO)c(=O)n2C,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20030114311A1,Nc1ccccc1O.O=C(Cl)c1cc(Cl)c(Cl)c(Cl)n1>>O=C(Nc1ccccc1O)c1cc(Cl)c(Cl)c(Cl)n1,,ClCCl,,CCN(CC)CC,,test
US20120071489A1,CC(C)(C)c1ccccc1N1CCN(C(=O)c2c[nH]cn2)CC1.COC(=O)CBr>>COC(=O)Cn1cnc(C(=O)N2CCN(c3ccccc3C(C)(C)C)CC2)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120225854A1,CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)CC2COCc2ccccc2)cc1)C(F)(F)F.CS(=O)(=O)Cl>>CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)CC2COS(C)(=O)=O)cc1)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20080063602A1,COc1c(OC)c2c(c(OC)c1C(=O)O)C1C=CC2C1.O=C1CCC(=O)N1O>>COc1c(OC)c2c(c(OC)c1C(=O)ON1C(=O)CCC1=O)C1C=CC2C1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US06506901B2,CS(=O)(=O)Nc1cc([C@@H](O)CN)ccc1O.O=CC1CCN(c2ccc(C(=O)N[C@H](CC(=O)OCc3ccccc3)C(=O)OCc3ccccc3)cc2)CC1>>CS(=O)(=O)Nc1cc([C@@H](O)CNCC2CCN(c3ccc(C(=O)N[C@H](CC(=O)OCc4ccccc4)C(=O)OCc4ccccc4)cc3)CC2)ccc1O,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US06936602B1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3)cc1.O=Cc1ccccc1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3Cc2ccccc2)cc1,,ClCCCl,O,O=C([O-])O.[Na+],,test
US20140179648A1,BrCc1ccccc1.O=c1[nH]cc(I)c2cnccc12>>O=c1c2ccncc2c(I)cn1Cc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110034696A1,Br.CC(NC(=O)c1cc(Cl)ccc1NC(=O)C1CC(OS(=O)(=O)c2ccccc2[N+](=O)[O-])=NN1c1ncccc1Cl)C1CC1>>CC(NC(=O)c1cc(Cl)ccc1NC(=O)C1CC(Br)=NN1c1ncccc1Cl)C1CC1,,CC(=O)O,O,CCOC(C)=O,[Na+].[OH-],test
US05455262,C[C@H](SC(C)(C)C)C(=O)O>>C[C@@H](CO)SC(C)(C)C,,C1CCOC1,,B,,test
US20120225854A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Nc1ccc(S(=O)(=O)c2ccc(Br)cn2)cn1>>CC1(C)OB(c2ccc(S(=O)(=O)c3ccc(N)nc3)nc2)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20150291572A1,C=CCBr.O=Cc1ncc(Br)cc1Cl>>C=CCC(O)c1ncc(Br)cc1Cl,[Zn],C1CCOC1,O,[Cl-].[NH4+],,test
US20110015173A1,COc1cnc2c(c1)c(-c1cc(Cl)nc(NC3CCCCC3)c1)cn2S(=O)(=O)c1ccccc1>>O=S(=O)(c1ccccc1)n1cc(-c2cc(Cl)nc(NC3CCCCC3)c2)c2cc(O)cnc21,,ClCCl,ClCCl,BrB(Br)Br,,test
US20150274733A1,COC(=O)CBr.COC(=O)CC(C)(C)N>>COC(=O)CNC(C)(C)CC(=O)OC,,C1CCOC1,CC#N,CCN(C(C)C)C(C)C,Cl,test
US20020099073A1,C[C@@H](c1ccccc1)N1Cc2sc(N)c(C(=O)OC(C)(C)C)c2C[C@H]1CN.O=C=Nc1ccc(Oc2ccccc2)cc1>>C[C@H](c1ccccc1)N1Cc2sc(N)c(C(=O)OC(C)(C)C)c2C[C@H]1CNC(=O)Nc1ccc(Oc2ccccc2)cc1,,ClCCl,,,,test
US05852023,CSC(C)c1ncnc(N[C@H]2CC[C@@H](C(C)(C)C)CC2)c1Cl.O=C(OO)c1cccc(Cl)c1>>CC(c1ncnc(N[C@H]2CC[C@@H](C(C)(C)C)CC2)c1Cl)S(C)=O,,CC(Cl)Cl,ClCCl,,,test
US20080188521A1,C[Si](C)(C)C#CC1(O)CCOCC1>>C#CC1(O)CCOCC1,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20020028807A1,CCN1c2nc(C(F)(F)F)ccc2NC(=O)c2cc(Br)cnc21.CI>>CCN1c2ncc(Br)cc2C(=O)N(C)c2ccc(C(F)(F)F)nc21,,CN(C)C=O,O,[H-].[Na+],,test
US06355642B1,COc1ccccc1C1CNCCN1CCCCC12CCCc3c(OC(C)=O)ccc(c31)NC2=O>>COc1ccccc1C1CNCCN1CCCCC12CCCc3c(O)ccc(c31)NC2=O,,CO,,C[O-].[Na+],,test
US20120230951A1,COC(=O)N[C@@H](C(=O)O)c1ccccc1.COC(=O)N[C@H]1CCc2ccn3c2C1C(=O)C[C@H](c1ncc(-c2ccc(-c4ccc(-c5cnc([C@@H]6COCCN6)[nH]5)cc4)cc2)[nH]1)C3>>COC(=O)N[C@@H](C(=O)N1CCOC[C@H]1c1ncc(-c2ccc(-c3ccc(-c4cnc([C@H]5CC(=O)C6c7c(ccn7C5)CC[C@@H]6NC(=O)OC)[nH]4)cc3)cc2)[nH]1)c1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04082912,CC(C)(C)OC(=O)N=[N+]=[N-].NCc1ccsc1CC(=O)O>>CC(C)(C)OC(=O)NCc1ccsc1CC(=O)O,,CC(C)=O,,CCN(CC)CC,,test
US20130310391A1,NCCO.[O-][n+]1ccc2c(Br)cccc2c1>>Nc1nccc2c(Br)cccc12,,c1ccncc1,,CS(=O)(=O)Cl,,test
US04666923,CC(=O)Nc1cc2c(cc1[N+](=O)[O-])C(CC(C)C)C(=O)N2>>CC(C)CC1C(=O)Nc2cc(N)c([N+](=O)[O-])cc21,,CCO,,,,test
US06211215B1,Cl.O=Cc1ccc(OCc2coc(/C=C/c3ccccc3)n2)cc1>>ClCc1ccc(OCc2coc(/C=C/c3ccccc3)n2)cc1,,CCO,O,C1CCOC1,[BH4-].[Na+],test
US20140235647A1,C1COCCN1.Cc1ccncc1-c1ccnc2c(Cl)noc12>>Cc1ccncc1-c1ccnc2c(N3CCOCC3)noc12,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04417050,C=CCBr.OCc1cccc2c(-c3ncccn3)cccc12>>C=CCOCc1cccc2c(-c3ncccn3)cccc12,,O,,C1CCOC1,[H-].[Na+],test
US20060122399A1,CI.CN(C)C=O.N#CCc1ccc(Br)cc1Cl>>CC(C)(C#N)c1ccc(Br)cc1Cl,,C1CCOC1,,[H-].[Na+],,test
US20100222345A1,Nc1cc(C(F)(F)F)ccc1[N+](=O)[O-].O=C1CCC(=O)N1Br>>Nc1cc(C(F)(F)F)c(Br)cc1[N+](=O)[O-],,CC(=O)O,,O,,test
US20010003747A1,COc1ccc2c(c1)N(CCNC(=O)c1ccccc1)CC(c1ccccc1)O2.O=C=Nc1ccccc1>>COc1ccc2c(c1)N(CCNC(=O)Nc1ccccc1)CC(c1ccccc1)O2,,c1ccncc1,,Cl,O,test
US06613760B1,CCOC(=O)c1cc2c(COC3CCCCO3)cccc2n1Cc1ccc(Cl)c(Cl)c1>>CCOC(=O)c1cc2c(CO)cccc2n1Cc1ccc(Cl)c(Cl)c1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20010007873A1,COc1ccc(C=O)c(OCc2ccccc2)c1.O=C1CCC(=O)N1Br>>COc1cc(OCc2ccccc2)c(C=O)cc1Br,,ClC(Cl)(Cl)Cl,,,,test
US20070066639A1,CCOCC(=O)Nc1c(NCCCOC(C)=O)c(C)c(C)n2nnnc12>>CCOCc1nc2c(c(C)c(C)n3nnnc23)n1CCCO,,CCO,O,O=C([O-])[O-].[K+].[K+],,test
US20100137250A1,CS(=O)(=O)c1ccc(C(=O)c2cc(CC(=O)O)cc3ccc(F)cc23)c(Cl)c1>>CS(=O)(=O)c1ccc(C(O)c2cc(CC(=O)O)cc3ccc(F)cc23)c(Cl)c1,,CO,,[BH4-].[Na+],,test
US20090131472A1,C[Si](C)(C)C#CC(=O)C(c1cccc(-c2ccc(F)cc2F)n1)c1cc(C#N)ccc1F>>C#CC(=O)C(c1cccc(-c2ccc(F)cc2F)n1)c1cc(C#N)ccc1F,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20150183799A1,CC[C@@H](CNC(=O)OC(C)(C)C)c1ccc(-c2c(OC)cc(C)c3[nH]c(=O)c4sccc4c23)cc1>>CC[C@@H](CN)c1ccc(-c2c(OC)cc(C)c3[nH]c(=O)c4sccc4c23)cc1,,CCOCC,,Cl,,test
US20090264401A1,CC(=O)N1CCNCC1.CCCSc1nc(Cl)ncc1C(=O)NC1C2CC3CC(C2)CC1C3>>CCCSc1nc(N2CCN(C(C)=O)CC2)ncc1C(=O)NC1C2CC3CC(C2)CC1C3,,C1CCOC1,CCOC(C)=O,,,test
US20110281842A1,Brc1cn[nH]c1.Cn1cc(-c2cc3c(Cl)c(Cl)cnc3n2COCC[Si](C)(C)C)cn1>>Cn1cc(-c2cc3c(-n4cc(Br)cn4)c(Cl)cnc3n2COCC[Si](C)(C)C)cn1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US07005440B1,O=Cc1c(F)cccc1C(F)(F)F.OCc1cccc(OCc2ccc3ccccc3n2)c1>>O=Cc1c(OCc2cccc(OCc3ccc4ccccc4n3)c2)cccc1C(F)(F)F,,CN(C)C=O,,[H-].[Na+],,test
US05281614,CCCCC(=O)Cl.CCCCc1nn(-c2cc(N)ccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1>>CCCCC(=O)Nc1ccc(Cl)c(-n2nc(CCCC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)OC(C)(C)C)cc3)c2=O)c1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20120202785A1,Cc1c(F)ccc([N+](=O)[O-])c1Nc1ccccc1>>Cc1c(F)ccc(N)c1Nc1ccccc1,[Fe],O,,CO,[Cl-].[NH4+],test
US20020107418A1,CCOc1ccc(C[C@H](N)C(=O)O)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCOc1ccc2c(c1)C(=O)[C@@H](NC(=O)C(F)(F)F)C2,,ClCCl,,,,test
US20110218200A1,O=C(O)c1ccc(N2CCN(C(=O)c3ccccc3)CC2)cc1[N+](=O)[O-]>>Nc1cc(N2CCN(C(=O)c3ccccc3)CC2)ccc1C(=O)O,O=[Pt],C1CCOC1,CCO,,,test
US05824691,COC(=O)c1cc(C=O)cc(-n2cccc2)c1.NCCO>>COC(=O)c1cc(CNCCO)cc(-n2cccc2)c1,,CO,,[BH4-].[Na+],,test
US06380218B1,COc1ccc(CNC(=O)c2cccnc2Oc2ccc(F)cc2)cc1>>O=C(NCc1ccc(O)cc1)c1cccnc1Oc1ccc(F)cc1,,CCOCC,,,,test
US20110034440A1,CC(=O)N1CCC(N(C)C(=O)CN(CC(=O)NCCNC(C)C)c2cc(-c3noc(C)n3)ccc2C)CC1.Cl>>CC(=O)N1CCC(N(C)C(=O)CN(CC(=O)NCCNC(C)C)c2cc(-c3noc(C)n3)ccc2C)CC1.Cl,,CCOC(C)=O,,CCOCC,,test
US20090181943A1,COc1ccc(/C=N/C(c2ccccc2)c2ccccc2)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(C2ON2C(c2ccccc2)c2ccccc2)cc1,,ClCCl,,,,test
US20110065681A1,Cc1ccc(-c2cc(Oc3nccs3)cc(C(=O)O)c2)cc1.Cc1ncc([C@@H](C)N)cn1>>Cc1ccc(-c2cc(Oc3nccs3)cc(C(=O)N[C@H](C)c3cnc(C)nc3)c2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160222033A1,CC[Mg]Br.CON(C)C(=O)c1csc(NC(=O)OC(C)(C)C)n1>>CCC(=O)c1csc(NC(=O)OC(C)(C)C)n1,,[Cl-],[NH4+],C1CCOC1,,test
US20150087646A1,NCc1ccc(Cl)c(-c2nn(-c3ccc(C(F)(F)F)cc3)c(=O)[nH]2)c1.O=C(Cl)c1ccno1>>O=C(NCc1ccc(Cl)c(-c2nn(-c3ccc(C(F)(F)F)cc3)c(=O)[nH]2)c1)c1ccno1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20100168080A1,C[C@H]1CO[C@H](Cc2ccc(F)cc2)CN1Cc1ccccc1>>C[C@H]1CO[C@H](Cc2ccc(F)cc2)CN1,[Pd],CCO,,,,test
US20160168156A1,C1CNCCN1.Fc1ccc(F)c([C@H]2CCCN2c2ccn3ncc(-c4nnc(Br)s4)c3n2)c1>>Fc1ccc(F)c([C@H]2CCCN2c2ccn3ncc(-c4nnc(N5CCNCC5)s4)c3n2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20070185184A1,CC(=O)c1c[nH]c2ccccc12.N#Cc1ccc(F)c(Cl)c1>>CC(=O)c1cn(-c2ccc(C#N)cc2Cl)c2ccccc12,,CN(C)C=O,O,CCCCCC,[H-].[Na+],test
US20100160424A1,COC(=O)Cl.COC(=O)c1cccc(C(OCCN)c2cc(F)cc(Cl)c2)c1>>COC(=O)NCCOC(c1cc(F)cc(Cl)c1)c1cccc(C(=O)OC)c1,,ClCCl,,CCN(CC)CC,,test
US20050037977A1,CN[C@H](C(=O)N[C@H](C(=O)N(C)[C@H](/C=C(\C)C(=O)N(C)OC)C(C)C)C(C)(C)C)C(C)(C)c1ccccc1.c1cscn1>>CN[C@H](C(=O)N[C@H](C(=O)N(C)[C@H](/C=C(\C)C(=O)c1nccs1)C(C)C)C(C)(C)C)C(C)(C)c1ccccc1,,C1CCOC1,,CN(C)CCN(C)C,[Li]CCCC,test
US20060128793A1,COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CC[C@H](O)[C@@]2(C)C[C@H]1OC(C)=O.c1ccc(CNCC23CCCN(CCC2)C3)cc1>>COCC1OC(=O)C(=CN(Cc2ccccc2)CC23CCCN(CCC2)C3)C2=C(O)C(=O)C3=C(C(OC(C)=O)CC4(C)C(O)CCC34)C21C,,ClCCl,,CCN(CC)CC,Cl,test
US20120128761A1,CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OCCCCCCCCCC(O)CC=O)CC[C@]4(C)[C@H]3CC[C@]12C>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OCCCCCCCCCC(O)CCO)CC[C@]4(C)[C@H]3CC[C@]12C,,C1COCCO1,,CO,[BH4-].[Na+],test
US20150266881A1,CC(C)(C)OC(=O)N(CC1CC1)[C@@H]1C[C@H]1c1cccc(C(=O)NC2CCC(F)(F)CC2)c1.Cl>>Cl.O=C(NC1CCC(F)(F)CC1)c1cccc([C@@H]2C[C@H]2NCC2CC2)c1,,C1CCOC1,CO,CCOC(C)=O,,test
US20090143381A1,CC(=O)Cl.NCc1cccc(-c2nc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)cc3ccccc23)c1>>CC(=O)NCc1cccc(-c2nc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)cc3ccccc23)c1,,CN(C)C=O,,CCN(CC)CC,,test
US20150225404A1,CC(C)(C)[Si](C)(C)OCc1cncc(-c2cc(OCc3cccc(C#N)c3)nc3c2CCC3)n1>>N#Cc1cccc(COc2cc(-c3cncc(CO)n3)c3c(n2)CCC3)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20060004013A1,COc1cc(/C=C(\CCNCc2cccc(F)c2)C(=O)OC(C)(C)C)ccc1-n1cnc(C)c1>>COc1cc(/C=C2\CCN(Cc3cccc(F)c3)C2=O)ccc1-n1cnc(C)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130065890A1,CO.Nc1ccnc(Cl)n1>>COc1nccc(N)n1,,CO,,C[O-].[Na+],,test
US20040063707A1,CC(=O)Cl.CCOC(=O)c1cn2nc[nH]c(=O)c2c1C(C)C.NN>>Cc1nnc(-c2cn3nc[nH]c(=O)c3c2C(C)C)o1,,O,,,,test
US05541335,CNC(=C[N+](=O)[O-])SC.NCCSCc1csc(CO)n1>>CNC(=C[N+](=O)[O-])NCCSCc1csc(CO)n1,,CN(C)C=O,,,,test
US20090163488A1,O=C(O)c1cc(Oc2cccc([N+](=O)[O-])c2)ccn1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Nc1cc(Oc2cccc([N+](=O)[O-])c2)ccn1,,O,,CCN(CC)CC,CN(C)C=O,test
US06031107,COC(=O)C(=COCF)c1ccccc1OC1CCCCO1>>COC(=O)C(=COCF)c1ccccc1O,,CO,,,,test
US20030232812A1,CC(=O)NC[C@H]1CN(c2ccc(C3=CCS(=O)(=O)CC3)c(F)c2)C(=O)O1.CS(N)(=O)=O>>CC(=O)NC[C@H]1CN(c2ccc(C3(O)C=CS(=O)(=O)CC3)c(F)c2)C(=O)O1,,CC(C)(C)O,O,O=S([O-])[O-].[Na+].[Na+],,test
US20080176870A1,Cc1cc(C(=O)NC2c3ccccc3CC2O)nc2cc(C(=O)O)nn12.OCc1cc2ccccc2o1>>Cc1cc(C(=O)N[C@@H]2c3ccccc3C[C@@H]2O)nc2cc(C(=O)OCc3cc4ccccc4o3)nn12,CN(C)c1ccncc1,C1CCOC1,,CCN=C=NCCCN(C)C,Cl,test
US20030008360A1,CC(=O)Cl.O=C1NC2C=CC1C2>>CC(=O)N1C(=O)C2C=CC1C2,,CC#N,,O,c1ccncc1,test
US20060155128A1,CS(=O)(=O)Cl.Cc1nc(CO)ccc1[N+](=O)[O-]>>Cc1nc(COS(C)(=O)=O)ccc1[N+](=O)[O-],,C1CCOC1,,CCN(CC)CC,,test
US20150337004A1,C=C(C)[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(C)=O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CC1(C)[C@H](C(=O)OCc2ccccc2)C[C@@H]1C(=O)OC(=O)c1c(Cl)cc(Cl)cc1Cl>>C=C(C)[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(=O)C6CC(C(=O)OCc7ccccc7)C6(C)C)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,CN(C)c1ccncc1,c1ccncc1,,,,test
US20080076745A1,CC(C)(C)OC(=O)NCCC[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H](CO)CNC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCC[C@H](N)C(=O)N[C@H](CO)CNC(=O)OC(C)(C)C,[Pd],CCO,,,,test
US20140221330A1,CC(C)(C)[Si](C)(C)Cl.O=C(CCc1ccc(O)cc1)OCc1ccccc1>>CC(C)(C)[Si](C)(C)Oc1ccc(CCC(=O)OCc2ccccc2)cc1,,ClCCl,O,c1c[nH]cn1,,test
US20100256126A1,CCOC(=O)C1CCN(C(=O)OC(C)(C)C)CC1.IC1CCCC1>>CCOC(=O)C1(C2CCCC2)CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,,,test
US20060223849A1,COC(=O)c1cccc(NC(=O)c2cc3ccccc3cn2)c1N>>O=C(O)c1cccc2[nH]c(-c3cc4ccccc4cn3)nc12,,CC(=O)O,,C,O=C[O-].[NH4+],test
US20150175604A1,CCCC[Sn](CCCC)(CCCC)c1ccccn1.Clc1ccc2c(cc(Br)n2Cc2ccccc2)n1>>Clc1ccc2c(cc(-c3ccccn3)n2Cc2ccccc2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US08785655B2,COC(=O)[C@H](O)c1ccccc1.O=C(Br)CBr>>COC(=O)[C@H](OC(=O)CBr)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20080242658A1,CC1C(=NOCc2ccccc2)CCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C1CCCCC1>>N[C@H](C(=O)N1CCCC1C=NOCc1ccccc1)C1CCCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04491628,C1CCOC1.CC(=O)c1ccc(O)cc1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=C(C)c1ccc(OC(=O)OC(C)(C)C)cc1,,C1CCOC1,,O,CC(C)(C)[O-].[K+],test
US06326359B1,COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CC#N)nc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C>>COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CCN)nc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C,[Ni],CCO,,N,[H][H],test
US05952369,C1=COCCC1.O[C@@H]1CCN(Cc2ccccc2)C1>>c1ccc(CN2CC[C@@H](OC3CCCCO3)C2)cc1,,ClCCl,,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US20110183953A1,C=CS(=O)(=O)N[C@@H]1CCc2c(-c3cnc(-c4ccc(OC(C)C)c(C#N)c4)s3)cccc21.O[C@@H]1CCCNC1>>CC(C)Oc1ccc(-c2ncc(-c3cccc4c3CC[C@H]4NS(=O)(=O)CCN3CCC[C@@H](O)C3)s2)cc1C#N,,CN(C)C=O,,Cl,,test
US05442115,CC(=O)CC(=O)Nc1ccccc1.ClCl>>CC(=O)C(Cl)C(=O)Nc1ccccc1,,Cc1ccccc1,O,,,test
US20150225390A1,CC1CC(=O)CCN1C(=O)OC(C)(C)C.NC1CC1>>CC1CC(NC2CC2)CCN1C(=O)OC(C)(C)C,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130150391A1,COc1nc(N2CCC(OC)CC2)nc(OC)c1[N+](=O)[O-]>>COc1nc(N2CCC(OC)CC2)nc(OC)c1N,[Pd],CO,,,,test
US20120115845A1,NC(=O)c1cc(O)ccc1Cl.OCCBr>>NC(=O)c1cc(OCCBr)ccc1Cl,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04885022,CCS.COC(=O)c1ccc(S(C)(=O)=O)c(CBr)c1Cl>>CCSCc1c(S(C)(=O)=O)ccc(C(=O)OC)c1Cl,,ClC(Cl)Cl,,C1CCOC1,O=C([O-])[O-].[K+].[K+],test
US05654472,CC(=O)OC(C)=O.OCC1(O)COC(O)(CO)CO1>>CC(=O)OCC(=O)COC(C)=O,CN(C)c1ccncc1,c1ccncc1,,CO,,test
US20140275071A1,CI.Cn1c(=O)n(CS(N)(=O)=O)c(=O)c2c1nc(Oc1cccc(OC(F)(F)F)c1)n2Cc1ccc(Cl)cc1>>CNS(=O)(=O)Cn1c(=O)c2c(nc(Oc3cccc(OC(F)(F)F)c3)n2Cc2ccc(Cl)cc2)n(C)c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090270355A1,CC(C)S(=O)(=O)Cl.CCCCc1cc(OC2CCN(CCCCN)CC2)c2ncccc2c1.ClCCl>>CCCCc1cc(OC2CCN(CCCCNS(=O)(=O)C(C)C)CC2)c2ncccc2c1.Cl.Cl,,ClCCl,,CCN(CC)CC,,test
US20060142265A1,COC(=O)[C@@H]1CCCN1Cc1cc(Br)cnc1N>>O=C1Nc2ncc(Br)cc2CN2CCC[C@@H]12,,CS(C)=O,O,[H-].[Na+],,test
US20020151561A1,CC(=O)Cl.COc1ccc(CN2CCc3c(sc(N)c3C(=O)OC(C)(C)C)C2CN)cc1>>COc1ccc(CN2CCc3c(sc(N)c3C(=O)OC(C)(C)C)C2CNC(C)=O)cc1,,ClCCl,,,,test
US20110190257A1,C=COCCONC(=O)c1ccc2cnsc2c1Nc1ccc(Br)cc1F>>O=C(NOCCO)c1ccc2cnsc2c1Nc1ccc(Br)cc1F,,CO,,Cl,,test
US05512562,COc1ccc2c(c1OC)CCN(C)CC2c1cccc2ccoc12>>CN1CCc2c(ccc(O)c2O)C(c2cccc3ccoc23)C1,,ClCCl,,BrB(Br)Br,,test
US06472386B1,CC(C)(C)[Si](C)(C)Cl.COC(=O)[C@@H](N)CO>>COC(=O)[C@@H](N)CO[Si](C)(C)C(C)(C)C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,Cl,test
US20100004233A1,CCO.CCOC(=O)CS(=O)(=O)Nc1cccc(NC(C)=O)c1.O=Cc1ccc(O)cc1O>>CC(=O)Nc1cccc(NS(=O)(=O)c2c(C)c3ccc(O)cc3oc2=O)c1,,CCO,,C1CCNCC1,,test
US20090118282A1,CC(C)(C)OC(=O)Nc1cc(CN2CCCCC2)ccc1O.FC(F)(F)c1ccc2c(SCCCCCBr)ccnc2c1>>CC(C)(C)OC(=O)Nc1cc(CN2CCCCC2)ccc1OCCCCCSc1ccnc2cc(C(F)(F)F)ccc12,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04923984,COC(=O)C=CC(=O)c1ccccc1N>>COC(=O)CCC(=O)c1ccccc1N,[Pd],CO,O,,,test
US20090170790A1,Clc1ncc(-c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)cn1>>Clc1ncc(-c2c[nH]cn2)cn1,,CCO,,Cl,,test
US20110275608A1,CC(C)(C)OC(=O)N1CCC(Cn2ccc3c(Cl)c(Cl)ccc3c2=O)CC1.Cl>>Cl.O=c1c2ccc(Cl)c(Cl)c2ccn1CC1CCNCC1,,C1COCCO1,,,,test
US20070032540A1,CCCN(CCC)CCc1cccc2[nH]ccc12.O=C1CCC(=O)N1Cl>>CCCN(CCC)CCc1cccc2c1=CC(=O)N=2,,Cc1ccccc1,,,,test
US20040242580A1,CCCCN1N=C(c2ccc(Cl)c(Cl)c2)NCC1=O.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CCCCN1N=C(c2ccc(Cl)c(Cl)c2)NCC1=S,,Cc1ccccc1,,,,test
US05097061,C=Cc1ccccc1CC(C)C>>CCc1ccccc1CC(C)C,[Pd],,,,,test
US20040110763A1,C=O.CC(=O)O.CC(C)n1nc(-c2c(-c3ccccc3)nn3ccc(N)cc23)ccc1=O.CCOC(C)=O.CO>>COCN(COC)c1ccn2nc(-c3ccccc3)c(-c3ccc(=O)n(C(C)C)n3)c2c1,,CO,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05208228,CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(=O)C(OC)C3)C(C)C(O)CC1=O)C(C)CC2OC.NCc1ccccc1>>CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(NCc4ccccc4)C(OC)C3)C(C)C(O)CC1=O)C(C)CC2OC,,CC(C)O,,[BH3-]C#N.[Na+],,test
US20140155395A1,Cn1nc(C(C)(C)C)c(Cl)c1C(=O)Nc1nc(Br)ccc1[N+](=O)[O-].OB(O)c1ccccc1Cl>>Cn1nc(C(C)(C)C)c(Cl)c1C(=O)Nc1nc(-c2ccccc2Cl)ccc1[N+](=O)[O-],,COCCOC,O,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],test
US06008243,CNC(=O)[C@@H](NC(=O)[C@@H](CC(=O)OCc1ccccc1)n1ccc(-c2ccc(C#N)cc2)c1)C(C)(C)C>>CNC(=O)[C@@H](NC(=O)[C@@H](CC(=O)O)n1ccc(-c2ccc(C#N)cc2)c1)C(C)(C)C,,CCOC(C)=O,CO,,,test
US20120309757A1,COC(=O)c1ccc2[nH]cc(C=O)c2c1>>COC(=O)c1ccc2[nH]cc(C)c2c1,,CCOC(C)=O,CN(C)C=O,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20040009995A1,CN1CCOCC1.CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2CO)c1>>CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2CN2CCOCC2)c1,,ClCCl,,CCN(C(C)C)C(C)C,CS(=O)(=O)Cl,test
US04861769,CCOC(=O)C(=NOC1CC1(F)Br)C1(C)OCCO1>>CCOC(=O)C(=NOC1CC1F)C1(C)OCCO1,,c1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,CCCC[SnH](CCCC)CCCC,test
US05525723,CCOC(=O)N1C(=O)c2ccccc2C1=O.N[C@@H](Cc1ccsc1)C(=O)O>>O=C(O)[C@H](Cc1ccsc1)NN1C(=O)c2ccccc2C1=O,,C1COCCO1,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20120157482A1,Cc1cc(N)cc(C)c1Oc1cc(Cl)ncn1.O=C=Nc1cccc(C(F)(F)F)c1>>Cc1cc(NC(=O)Nc2cccc(C(F)(F)F)c2)cc(C)c1Oc1cc(Cl)ncn1,,C1CCOC1,,CO,,test
US20080039426A1,CCOC(=O)C(C)(C(C)=O)c1ccc(N)c(NC)c1C#N.Cc1cc(F)ccc1N=C=S>>CCOC(=O)C(C)(C(C)=O)c1ccc2nc(Nc3ccc(F)cc3C)n(C)c2c1C#N,,C1CCOC1,,,,test
US20040019033A1,CS(=O)(=O)Cl.OCc1cc(Cl)cc(OC(F)(F)F)c1>>CS(=O)(=O)OCc1cc(Cl)cc(OC(F)(F)F)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20060142333A1,O=C(Nc1ccc2c(c1)N(C(=O)C(F)(F)F)CCC2)c1ccc(-c2ccccc2)nc1>>O=C(Nc1ccc2c(c1)NCCC2)c1ccc(-c2ccccc2)nc1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20150315209A1,O=C(CCl)c1ccccc1.O=C(OCc1ccccc1)N1CCNCC1>>O=C(CN1CCN(C(=O)OCc2ccccc2)CC1)c1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110172187A1,O=C(O)Cc1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(CCO)c1,,C1CCOC1,,B,,test
US20130137848A1,Nc1cc(Cl)c([N+](=O)[O-])cc1N.O=S(Cl)Cl>>O=[N+]([O-])c1cc2nsnc2cc1Cl,,ClCCl,,O=C([O-])O.[Na+],,test
US20060003998A1,CC(Cl)OC(=O)Cl.OC(Cc1ccccc1SC(F)(F)F)(c1ccccc1)C1CN(Cc2ccccc2)CCO1>>CC(=O)O[C@@](Cc1ccccc1SC(F)(F)F)(c1ccccc1)[C@H]1CNCCO1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20020188125A1,C=COC(C)=O.CC(=O)[O-].CCCCCC.CCOC(C)=O.ClCCl>>CCOC(C[C@H](CO)COC(C)=O)OCC,,ClCCl,,,,test
US20020013328A1,CC(C)c1[nH]n(-c2c(Cl)cc(Cl)cc2Cl)c2nc(Cc3ccc(N)cc3)nc(=O)c1-2.O=C(Cl)CCl>>CC(C)c1[nH]n(-c2c(Cl)cc(Cl)cc2Cl)c2nc(Cc3ccc(NC(=O)CCl)cc3)nc(=O)c1-2,,C1CCOC1,CN(C)C=O,CCN(CC)CC,,test
US20100069365A1,C1CCC(NC2CC2)CC1.O=C(Br)CBr>>O=C(CBr)N(C1CCCCC1)C1CC1,,ClCCl,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20080274944A1,C1CCOC1.O=C(Oc1ccccc1)c1ccccc1O>>C/C=C/C=C/COC(=O)c1ccccc1O,,C1CCOC1,,,,test
US04659708,COc1cc(NC(=O)CCCCCBr)c2nccc(C)c2c1.c1ccc(N2CCNCC2)nc1>>COc1cc(NC(=O)CCCCCN2CCN(c3ccccn3)CC2)c2nccc(C)c2c1,,Cc1ccccc1,ClCCl,CCN(CC)CC,,test
US20120308588A1,CCCCOC(=O)[C@H](O)[C@H](N)Cc1ccccc1Cl.O=C(O)CCCc1ccccc1C(=O)O>>CCCCOC(=O)[C@H](O)[C@@H](Cc1ccccc1Cl)NC(=O)CCCc1ccccc1C(=O)O,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050234077A1,Fc1cccc(CBr)c1F.Nc1nc(S)nc2c1CC(=O)N2>>Nc1nc(SCc2cccc(F)c2F)nc2c1CC(=O)N2,,CN(C)C=O,,O,[H-].[Na+],test
US20090042725A1,Nc1ccccc1Br.OB(O)c1cc(Cl)cc(Cl)c1>>Nc1ccccc1-c1cc(Cl)cc(Cl)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US04772600,CCCNCCC.O=C(O)Cn1c(-c2ccc([N+](=O)[O-])cc2)nc2cccnc21>>CCCN(CCC)C(=O)Cn1c(-c2ccc([N+](=O)[O-])cc2)nc2cccnc21,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US04851413,COc1c(C)c(C)c(OC)c(C=O)c1C>>COc1c(C)c(C)c(OC)c(CO)c1C,,CCO,,[Na],,test
US20140179672A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCCC(C)(N)C#N>>CCCC(C)(C#N)NC(=O)OC(C)(C)C,,ClCCl,,,,test
US20100093757A1,CCOC[C@H](O)C(=O)Nc1ccc(Cl)cn1.Cn1ccnc1-n1ncc2c(Oc3ccccc3)ncnc21>>CCOC[C@H](Oc1ncnc2c1cnn2-c1nccn1C)C(=O)Nc1ccc(Cl)cn1,,C1CCOC1,,[H-].[Na+],,test
US06399629B1,CCOC(=O)c1cnc2ccc(Cc3ccccc3)cc2c1>>O=C(O)c1cnc2ccc(Cc3ccccc3)cc2c1,,CCO,,[Na+].[OH-],,test
US20110110889A1,C1CCNCC1.CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]cc(C(=O)CCl)c3c2)c1F>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]cc(C(=O)CN4CCCCC4)c3c2)c1F,,CCO,,,,test
US20090012131A1,CC(C)c1nnc(N)s1.COc1ccc(-c2nc(COc3ccc(S(=O)(=O)Cl)cc3)co2)cc1>>COc1ccc(-c2nc(COc3ccc(S(=O)(=O)Nc4nnc(C(C)C)s4)cc3)co2)cc1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20090082329A1,CC(=O)Nc1cc(CN2C(=O)N(c3ccc(S(=O)(=O)C(F)(F)F)cc3)C(=O)C2(C)C)ccn1>>CC1(C)C(=O)N(c2ccc(S(=O)(=O)C(F)(F)F)cc2)C(=O)N1Cc1ccnc(N)c1,,CO,O,[Na+].[OH-],,test
US20040087577A1,C[C@@H]1CCCC(=O)C1.Nn1c(=O)c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2sccc21>>C[C@@H]1CCCC(=Nn2c(=O)c(C3=NS(=O)(=O)c4ccccc4N3)c(O)c3sccc32)C1,,CC(=O)N(C)C,,,,test
US06403818B1,C1CCOC1.CCCCN.Cc1ccc(C=O)cc1>>CCCCNC(=O)C(O)c1ccc(C)cc1,,CC#N,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20050124666A1,CS(=O)(=O)O.Cc1cc(S(F)(F)(F)(F)F)c(S(C)(=O)=O)cc1C(=O)NC(=N)N>>CS(=O)(=O)O.Cc1cc(S(F)(F)(F)(F)F)c(S(C)(=O)=O)cc1C(=O)NC(=N)N,,O,,,,test
US20120264735A1,O=c1ccn(-c2ccc(Cl)cc2)nc1C(O)c1cccc(OCc2ccccc2)c1>>O=c1ccn(-c2ccccc2)nc1Cc1cccc(O)c1,[Pd],CO,,,,test
US20150057268A1,CCCCC1(c2ccccc2)OC(=O)C2=C1CNCC2.O=C=NCc1ccccc1>>CCCCC1(c2ccccc2)OC(=O)C2=C1CN(C(=O)NCc1ccccc1)CC2,,ClCCl,,,,test
US05821241,BrCCBr.COC(=O)c1cc(C(=O)OC)[nH]n1>>COC(=O)c1cc(C(=O)OC)n(CCBr)n1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060211678A1,O=S(=O)(c1ccccc1)n1c(I)cc2c(Cl)ncnc21>>Clc1ncnc2[nH]c(I)cc12,,C1CCOC1,,[Na+].[OH-],,test
US20150218116A1,C1CCNC1.Cc1ccc(CS(=O)(=O)CCCOS(C)(=O)=O)cc1>>Cc1ccc(CS(=O)(=O)CCCN2CCCC2)cc1,,ClCCl,,,,test
US04009175,O=C1c2ccccc2C(=O)N1OCc1nnc2n1-c1ccc(C(F)(F)F)cc1C(c1ccccc1Cl)=NC2>>NOCc1nnc2n1-c1ccc(C(F)(F)F)cc1C(c1ccccc1Cl)=NC2,,CCO,,NN,O,test
US20060074075A1,CCOC(=O)c1c[nH]c2cccc(O)c2c1=O>>O=C(O)c1c[nH]c2cccc(O)c2c1=O,,[Na+],[OH-],,,test
US20090105259A1,COC[C@H]1CO1.NCCCCNS(=O)(=O)c1ccc(Cl)cc1Cl>>COC[C@H](O)CNCCCCNS(=O)(=O)c1ccc(Cl)cc1Cl,,CC(C)O,,,,test
US20080096882A1,Clc1nc(Cl)c2c(n1)CCS2.Nc1cccc(CN2CCOCC2)c1>>Clc1nc2c(c(Nc3cccc(CN4CCOCC4)c3)n1)SCC2,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05643908,BrCc1ccccc1.CCCCC[C@H](CC(=O)OC(C)(C)C)C(=O)O>>CCCCC[C@H](CC(=O)OC(C)(C)C)C(=O)OCc1ccccc1,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US04645765,NC(=O)OCC1c2c(O)cc(C=O)cc2N2CC3NC3C1(O)O2>>C=C1c2c(O)cc(C=O)cc2N2CC3NC3C1(O)O2,,[Na+],[OH-],Cl,,test
US20030087907A1,COc1cc2nccc(Oc3ccc(N)cc3F)c2cc1OC.Cc1cc(N)on1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)no4)cc3F)c2cc1OC,,ClC(Cl)Cl,O,CCN(CC)CC,,test
US20090137806A1,CS(=O)(=O)Cl.Cc1cc(F)ccc1-c1cc(N2CCC(CO)CC2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1cc(F)ccc1-c1cc(N2CCC(COS(C)(=O)=O)CC2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,ClCCl,O,CCN(CC)CC,,test
US20100016396A1,C#Cc1c(C)nn(C)c1Oc1cc(OCc2ccc(OC)cc2)c(Cl)cc1Cl.O=S(=O)(O)O>>CC(=O)c1c(C)nn(C)c1Oc1cc(O)c(Cl)cc1Cl,,C1CCOC1,,,,test
US20140343035A1,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1C[C@@H](OS(C)(=O)=O)C[C@H]1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,ClC(Cl)Cl,,CCN(CC)CC,O,test
US20090253687A1,O=C(O)c1cccnc1S>>OCc1cccnc1S,,C1CCOC1,,,,test
US20070049613A1,Cc1cc(Br)cc2c1C(=O)[C@@H]1CCN(Cc3ccccc3)C[C@H]21>>Cc1cc(Br)cc2c1CC1=C2CN(Cc2ccccc2)CC1,,OCCO,,NN,O,test
US20130237518A1,COC(=O)c1cncc(OC)c1>>COC(=O)C1CNCC(OC)C1,O=[Pt]=O,CO,Cl,,,test
US20140303143A1,COc1ccc(CN(c2ncns2)S(=O)(=O)c2cc3oc(=O)n([C@H](C)c4cccc5c4CN(C(=O)OC(C)(C)C)CC5)c3cc2Br)c(OC)c1>>C[C@H](c1cccc2c1CNCC2)n1c(=O)oc2cc(S(=O)(=O)Nc3ncns3)c(Br)cc21,,CO,,ClCCl,O=C(O)C(F)(F)F,test
US20030216570A1,CCOC(=O)/C=C(C)/C=C/[C@@H]1C[C@]1(C)c1cc(-c2c(C)cccc2C)c2c(c1)C(C)(C)CO2>>CC(/C=C/[C@@H]1C[C@]1(C)c1cc(-c2c(C)cccc2C)c2c(c1)C(C)(C)CO2)=C\C(=O)O,,CCCCCC,,CCO,[Na+].[OH-],test
US20150284408A1,CCOC(=O)CC#N.COc1ccc2c(c1)c(=O)oc(=O)n2C>>COc1ccc2c(c1)c(O)c(C#N)c(=O)n2C,,CN(C)C=O,,[H-].[Na+],,test
US20080300276A1,Cc1ccc(C=C2CCNCC2)cc1.O=C(O)c1nc2ccc(O)cc2[nH]1>>Cc1ccc(C=C2CCN(C(=O)c3nc4ccc(O)cc4[nH]3)CC2)cc1,,CC(C)O,,Cl,,test
US20070060570A1,Br.COc1ccc(S(=O)(=O)NCC#CC(=O)c2cc(OC)c(OC)c(OC)c2)cc1>>COc1ccc(S(=O)(=O)n2cc(Br)cc2-c2cc(OC)c(OC)c(OC)c2)cc1,,ClCCl,,CCOC(C)=O,O=C([O-])O.[Na+],test
US20140296562A1,CCCCCCCCCCCCCCCC(=O)C(NC(C)=O)C(=O)OC>>CCCCCCCCCCCCCCC[C@@H](O)[C@@H](NC(C)=O)C(=O)OC,,C1CCOC1,,O=CO,,test
US20150344468A1,CC(c1ccc2c(c1)sc(=O)n2COCC[Si](C)(C)C)c1ccn(-c2ccc(I)cn2)n1.OCC1CNCCO1>>CC(c1ccc2c(c1)sc(=O)n2COCC[Si](C)(C)C)c1ccn(-c2ccc(N3CCOC(CO)C3)cn2)n1,[Cu]Br,CN(C)C=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140221346A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CSc1ncc(Br)c([C@@H](N)Cc2cc(F)cc(F)c2)n1>>CSc1ncc(Br)c([C@H](Cc2cc(F)cc(F)c2)NC(=O)OC(C)(C)C)n1,,ClCCl,,CCN(CC)CC,Cl,test
US20040157836A1,BrBr.COC(=O)c1c(N)ccc2ccccc12>>COC(=O)c1c(N)c(Br)cc2c1CCCC2,,CN(C)C=O,ClC(Cl)Cl,,,test
US20100120793A1,CCOC(=O)C1(COc2ccc(-c3ccc(F)cc3)cc2)CCNC1.O=C=Nc1ccccc1Cl>>CCOC(=O)C1(COc2ccc(-c3ccc(F)cc3)cc2)CCN(C(=O)Nc2ccccc2Cl)C1,,ClCCl,,CCN(CC)CC,,test
US20020091148A1,NNC(=O)c1[nH]c2ccccc2c1-c1ccccc1Cl.O=Cc1ccc(Cl)cc1>>O=C(NN=Cc1ccc(Cl)cc1)c1[nH]c2ccccc2c1-c1ccccc1Cl,,CCO,,,,test
US20140349972A1,CCOP(C)(=O)c1ccc(-c2cc(-c3cnc(-c4ccccn4)nc3OCc3ccc(OC)cc3)on2)cc1>>CCOP(C)(=O)c1ccc(-c2cc(-c3cnc(-c4ccccn4)nc3O)on2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06911451B1,COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C.Clc1cncc(Cl)c1CCBr>>COC(=O)[C@H](Cc1ccc(OCc2c(Cl)cncc2Cl)cc1)NC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05866684,C#CC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1C)NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)CCC(=O)OC(C)(C)C)C(C)(C)C)C(OC)OC>>C#CCC(C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)CCC(=O)O)C(C)(C)C,,O=C(O)C(F)(F)F,,ClCCl,O,test
US20090137637A1,COC(=O)c1cc(-c2nn[nH]n2)cc(C)n1.NCc1ccc(F)cc1>>Cc1cc(-c2nn[nH]n2)cc(C(=O)NCc2ccc(F)cc2)n1,,C1CCOC1,Cc1ccccc1,C[Al](C)C,,test
US20100016164A1,Nc1ccccc1CN1CCCOC1=O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=C1OCCCN1Cc1ccccc1NS(=O)(=O)C(F)(F)F,,ClC(Cl)Cl,O,CCN(CC)CC,Cl,test
US05578620,[N-]=[N+]=NCC(O)COCCCc1ccccc1>>NCC(O)COCCCc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05475106,CC(O)c1cccc(N)c1.COc1cccc(N(CC(=O)N(C)c2ccccc2)C(=O)CN=C=O)c1>>COc1cccc(N(CC(=O)N(C)c2ccccc2)C(=O)CNC(=O)Nc2cccc(C(C)O)c2)c1,,C1CCOC1,,,,test
US20090214675A1,C/C(N)=C/C#N.CC(=O)CC(=O)OC(C)C(F)(F)F.Cc1cc(=O)c2cccc(C=O)c2o1>>CC1=C(C#N)C(c2cccc3c(=O)cc(C)oc23)C(C(=O)OC(C)C(F)(F)F)=C(C)N1,,CC(C)O,,CC(=O)O,,test
US20130237525A1,COC(=O)c1ccnc(-c2nc(C)cs2)c1>>Cc1csc(-c2cc(CO)ccn2)n1,,CO,,[BH4-].[Na+],,test
US20060025474A1,C#Cc1ccc(C(CC)(CC)c2ccc(O[Si](C)(C)C(C)(C)C)c(C)c2)cc1C.CCC1(C(=O)N(C)OC)CC1>>CCC1(C(=O)C#Cc2ccc(C(CC)(CC)c3ccc(O[Si](C)(C)C(C)(C)C)c(C)c3)cc2C)CC1,,C1CCOC1,,[Li]CCCC,,test
US20150368240A1,O=C(O)c1cnn(Cc2c[nH]nn2)c1.c1ccc2c(c1)CC(Nc1ncc3c(n1)CCNC3)C2>>O=C(c1cnn(Cc2c[nH]nn2)c1)N1CCc2nc(NC3Cc4ccccc4C3)ncc2C1,,CS(C)=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US05550134,C=CC[Sn](CCCC)(CCCC)CCCC.CN1C(=O)CC[C@]2(C)c3ccc(Br)cc3CC[C@@H]12>>C=CCc1ccc2c(c1)CC[C@H]1N(C)C(=O)CC[C@]21C,,CC#N,,,,test
US20160200725A1,BrC(Br)(Br)Br.CCN(CCO)C1CCN(C(=O)OC(C)(C)C)CC1>>CCN(CCBr)C1CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,,,test
US20060264415A1,CO.NCCc1ccc(C(=O)O)cc1>>COC(=O)c1ccc(CCN)cc1,O=S(=O)(O)O,,,Cl,,test
US03953415,CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC(C)(C)C>>CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)[C@@H](N)CC(=O)OC(C)(C)C)C(=O)N[C@@H](CCC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC(C)(C)C,[Pd],CC(=O)O,,,,test
US20020158255A1,CSC(=N)NC(=O)c1nc(Cl)c(N)nc1N.O=C(OCc1ccccc1)ON1C(=O)CCC1=O>>CSC(=N)N(C(=O)OCc1ccccc1)C(=O)c1nc(Cl)c(N)nc1N,,CCN(CC)CC,CN(C)C=O,I,,test
US20140350005A1,CN(C)C(=O)COC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(C(=O)OC(C)(C)C)CC3)C2=O)c1>>CN(C)C(=O)COC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCNCC3)C2=O)c1,,C1COCCO1,,Cl,,test
US20150105373A1,CCOC(=O)C(Cc1ccc(OC(F)(F)F)cc1)C(=O)OCC>>OCC(CO)Cc1ccc(OC(F)(F)F)cc1,,C1CCOC1,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20140206663A1,CCOC(=O)C(C)Br.O=C1COc2cc(F)c(Br)cc2N1>>CCOC(=O)C(C)N1C(=O)COc2cc(F)c(Br)cc21,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20060264435A1,CC1(C)OB(c2cc(C(F)(F)F)ccc2OCc2ccccc2)OC1(C)C>>CC1(C)OB(c2cc(C(F)(F)F)ccc2O)OC1(C)C,[Pd],CCOC(C)=O,,,,test
US20140329807A1,CCOC=O.N[C@@H]1CC[C@@H](Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1>>O=CN[C@@H]1CC[C@@H](Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1,,CN(C)C=O,,,,test
US20110212962A1,COCC(=O)Cl.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCc3ccncc3N)c3ccccc23)cc1>>COCC(=O)Nc1cnccc1COc1ccc(NC(=O)Nc2cc(C(C)(C)C)nn2-c2ccc(C)cc2)c2ccccc12,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,,test
US05912246,ClCc1cn2ccccc2n1.NC(=O)c1ccc(N2CCNCC2)cc1>>NC(=O)c1ccc(N2CCN(Cc3cn4ccccc4n3)CC2)cc1,,OCCO,,CCN(C(C)C)C(C)C,,test
US20030144338A1,CCCCCCCCCCOc1ccc(-n2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)OCC)cc2)cc1>>CCCCCCCCCCOc1ccc(-n2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)O)cc2)cc1,,C1CCOC1,CO,Cl,[K+].[OH-],test
US20090286882A1,CCOC(=O)CC1(CCC(CO)CCc2ccc(C(=O)OC)cc2)CC1>>CCOC(=O)CC1(CCC(C=O)CCc2ccc(C(=O)OC)cc2)CC1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US05491144,COC(=O)c1cc(Nc2ccccc2)c(Nc2ccccc2)cc1C(=O)OC.N>>O=C1NC(=O)c2cc(Nc3ccccc3)c(Nc3ccccc3)cc21,,OCCO,,,,test
US20150073011A1,CN.COC[C@@H]1C=C(C(=O)OC)[C@H](O)CN1C(=O)OC(C)(C)C>>CNC(=O)C1=C[C@@H](COC)N(C(=O)OC(C)(C)C)C[C@H]1O,,Cc1ccccc1,,C[Al](C)C,,test
US20110105459A1,COC(CCl)OC.Nc1cccc(Cl)n1>>Clc1cccc2nccn12,,CCO,O,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20120196894A1,CCOC(=O)CCC1=CCCCC1=O>>C1=C2CCCOC2CCC1,,C1CCOC1,CCOCC,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20080171748A1,CC(C)(C)OC(=O)N1C(=O)CC(=O)C[C@H]1C(=O)OCc1ccccc1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC2=CC(=O)N(C(=O)OC(C)(C)C)[C@H](C(=O)OCc3ccccc3)C2)cc1,,CCCCCCC,CCOC(C)=O,,,test
US05292732,COc1ccc2c(c1)CCc1ccn(CCNC(C)=O)c1-2.O=C(O)/C=C/C(=O)O>>COc1ccc2c(c1)CCc1cc3n(c1-2)CCN=C3C.O=C(O)/C=C/C(=O)O,,CCO,,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US20120157428A1,C[Mg]Cl.Cc1onc(C=O)c1-c1ccccc1C(=O)c1ccc(Cl)cc1>>Cc1onc(C(C)O)c1-c1ccccc1C(=O)c1ccc(Cl)cc1,,O,,C1CCOC1,[Cl-].[NH4+],test
US04508909,C=COCC(C)C.CSC(=S)NCCO>>CSC(=S)NCCC(C)OCC(C)C,,CCN(CC)CC,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04558043,Clc1cc2c(cc1N1CCCCC1)OCC2>>Clc1cc2ccoc2cc1N1CCCCC1,,C1COCCO1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US04174317,CN(C)CCCN.COc1cc(C=O)cc(OC)c1OC>>COc1cc(C=NCCCN(C)C)cc(OC)c1OC,,c1ccccc1,,,,test
US20110021514A1,CC(C)(c1ccc2c(n1)CC[C@@H](C(=O)O)C2)C(F)(F)F.Nc1ccc(Br)cc1>>CC(C)(c1ccc2c(n1)CC[C@@H](C(=O)Nc1ccc(Br)cc1)C2)C(F)(F)F,,C1COCCO1,,CCN(CC)CC,,test
US04483868,COc1ccc(OC)c(C(C)=O)c1.O=CC(=O)O>>COc1ccc(OC)c(C(=O)CC(O)C(=O)O)c1,,O,,,,test
US04973592,CI.O=C(OC1CNC(=N[N+](=O)[O-])NC1)C(c1ccccc1)c1ccccc1>>CN1CC(OC(=O)C(c2ccccc2)c2ccccc2)CNC1=N[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],,test
US05484763,COC(=O)Cc1nsc2ccc([N+](=O)[O-])cc12>>COC(=O)Cc1nsc2ccc(N)cc12,[Fe],CC(=O)O,,,,test
US04873236,CCN(CC)CCC1CCN(CCN)CC1.O=C1Nc2cccnc2N(C(=O)Cl)c2ccccc21>>CCN(CC)CCC1CCN(CCNC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1,,CCOC(C)=O,,,,test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4c(-c5ccccc5C(F)(F)F)cccc4nn23)CC1.Cl>>Cl.O=c1cc(C2CCNCC2)n2nc3cccc(-c4ccccc4C(F)(F)F)c3c2[nH]1,,C1COCCO1,,,,test
US20140329850A1,CC(C)(C)OC(=O)c1cc2c(ccn2CC2CC2)cn1>>O=C(O)c1cc2c(ccn2CC2CC2)cn1,,ClCCl,O=C(O)C(F)(F)F,,,test
US05856529,CC1(C)Cc2c(CO)cccc2O1>>CC1(C)Cc2c(C=O)cccc2O1,,CCN(CC)CC,,CS(C)=O,O=C(Cl)C(=O)Cl,test
US20140057902A1,CCC(O)c1cccc2c1CCN1C(=O)CNC(=O)C=C21>>CCC(=O)c1cccc2c1CCN1C(=O)CNC(=O)C=C21,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US20090181950A1,CC(C)(C)OC(=O)N1CCN(CCc2ccc(O[Si](C)(C)C(C)(C)C)cc2)CC1>>CC(C)(C)OC(=O)N1CCN(CCc2ccc(O)cc2)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140057895A1,NN.O=C(c1cccc(F)c1F)C(F)(F)F>>Fc1cccc2c(C(F)(F)F)n[nH]c12,,O,,C1COCCO1,,test
US20090029976A1,CCOC(=O)c1oc2cc(OC)ccc2c1C(C)C>>CCOC(=O)c1oc2cc(O)ccc2c1C(C)C,,ClCCl,,BrB(Br)Br,,test
US05514680,CC(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1[N+](=O)[O-]>>Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1[N+](=O)[O-],,CCO,Cl,,,test
US20040176367A1,CCOCc1nc2cnc3ccccc3c2n1NC(C)C.O=C(OO)c1cccc(Cl)c1>>CCOCc1nc2c[n+]([O-])c3ccccc3c2n1NC(C)C,,ClCCl,,,,test
US20150210688A1,COC(=O)c1cc(-c2[nH]c(COCc3ccccc3)nc2C(F)(F)F)c(C)cc1C>>COC(=O)c1cc(-c2[nH]c(CO)nc2C(F)(F)F)c(C)cc1C,[Pd],CO,,Cl,[H][H],test
US05770615,COc1ccc([C@H](NCC(O[Si](C)(C)C(C)(C)C)c2ccc(OCc3ccccc3)c(NS(C)(=O)=O)c2)C(=O)O)cc1>>COc1ccc([C@H](NCC(O[Si](C)(C)C(C)(C)C)c2ccc(O)c(NS(C)(=O)=O)c2)C(=O)O)cc1,[Pd],CO,,,,test
US20090036492A1,COC(Cl)Cl.Cc1cc(C)c(Br)cc1C.O>>Cc1cc(C)c(Br)c(C=O)c1C,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20050054024A1,BrCc1ccccc1.CC(C)(C)OC(=O)CN(CC(=O)OC(C)(C)C)c1ccccc1O>>CC(C)(C)OC(=O)CN(CC(=O)OC(C)(C)C)c1ccccc1OCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20060089367A1,Fc1cc2nc(COc3ccccc3)n(Cc3ccc(Cl)cc3)c2cc1N1CCNCC1.O=C(Cl)Cc1ccccc1>>O=C(Cc1ccccc1)N1CCN(c2cc3c(cc2F)nc(COc2ccccc2)n3Cc2ccc(Cl)cc2)CC1,,ClCCl,,,,test
US20130059834A1,Cn1nc(-c2cnc3[nH]cc(C(=O)NC4CCCC(NC(=O)OC(C)(C)C)C4)c3n2)c2ccc(Cl)cc21>>Cn1nc(-c2cnc3[nH]cc(C(=O)NC4CCCC(N)C4)c3n2)c2ccc(Cl)cc21,,CO,ClCCl,O=C(O)C(F)(F)F,,test
US05760246,Cc1ncc([N+](=O)[O-])[nH]1.O=C(Nc1cn(CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)cn1)c1ccccc1>>Cc1nc(NC(=O)c2ccccc2)cn1CCCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100016396A1,C=Cc1c(C(C)C)nn(C)c1Oc1cc(O[C@@H](C)C(=O)OC)c(Cl)cc1Cl>>C=Cc1c(C(C)C)nn(C)c1Oc1cc(O[C@@H](C)C(=O)O)c(Cl)cc1Cl,,C1CCOC1,O,Cl,[Li+].[OH-],test
US04970229,BrBr.CCCC[Sn](/C=C/[Sn](CCCC)(CCCC)CCCC)(CCCC)CCCC.COC(=O)CCCC(=O)c1ccccc1Br>>COC(=O)CCCC(=O)c1ccccc1/C=C/Br,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,ClC(Cl)(Cl)Cl,,Cc1ccccc1,,test
US20080292548A1,COC(=O)c1cc(N(C)C)ccc1Cl.COS(=O)(=O)C(F)(F)F>>COC(=O)c1cc([N+](C)(C)C)ccc1Cl.O=S(=O)([O-])C(F)(F)F,,CCOCC,,ClCCl,,test
US20080167286A1,N#Cc1cccc(C(N)=NO)c1.O=C(Cl)c1ccc(F)nc1>>N#Cc1cccc(-c2noc(-c3ccc(F)nc3)n2)c1,,c1ccncc1,,,,test
US05025036,BrCCCCCCc1cccc(OCc2ccccc2)c1OCc1ccccc1.O=C(OCc1ccccc1)c1ccc([N+](=O)[O-])c(O)c1>>O=C(OCc1ccccc1)c1ccc([N+](=O)[O-])c(OCCCCCCc2cccc(OCc3ccccc3)c2OCc2ccccc2)c1,,CC(C)=O,CN(C)C=O,[I-].[K+],O=C([O-])O.[Na+],test
US20050282819A1,CC1(C)c2ccc(C(Cl)CN3CCN(c4noc5ccccc45)CC3)cc2C(C)(C)C1O>>CC1(C)c2ccc(CCN3CCN(c4noc5ccccc45)CC3)cc2C(C)(C)C1O,,Cc1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,CCCC[SnH](CCCC)CCCC,test
US20150210682A1,CCOc1ccc(C=C(C)[N+](=O)[O-])cc1OCC>>CCOc1ccc(CC(C)N)cc1OCC,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20100286215A1,COC(=O)c1cc(I)ccc1F.O=C(Cl)c1ccc(Br)cc1>>COC(=O)c1cc(C(=O)c2ccc(Br)cc2)ccc1F,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20050070580A1,CCC(=O)OC(=O)CC.NCC1CN(c2ccc(N3C=CC(=O)CC3)c(F)c2)C(=O)O1>>CCC(=O)NCC1CN(c2ccc(N3C=CC(=O)CC3)c(F)c2)C(=O)O1,,CN(C)C=O,ClCCl,Cl,c1ccncc1,test
US20060287341A1,BrC(Br)(Br)Br.Cc1c(CO)ccc(C(F)(F)F)[n+]1[O-]>>Cc1c(CBr)ccc(C(F)(F)F)[n+]1[O-],,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20160207906A1,Cl.Cn1cc(Nc2nc(N)cc(-c3cccc(-n4ccc5cc(C6CC6)cc(F)c5c4=O)c3CO)n2)cn1>>Cl.Cn1cc(Nc2nc(N)cc(-c3cccc(-n4ccc5cc(C6CC6)cc(F)c5c4=O)c3CO)n2)cn1,,CCO,,CCOC(C)=O,,test
US20120040991A1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H]2C[C@H]1COc1ccc(C(F)(F)F)cn1>>FC(F)(F)c1ccc(OC[C@@H]2C[C@H]3C[C@H]3CN2)nc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060211603A1,COC(=O)CN.O=S(=O)(Cl)Cc1ccccc1>>COC(=O)CNS(=O)(=O)Cc1ccccc1,,ClCCl,,Cl,c1ccncc1,test
US20140296261A1,CCCS(=O)(=O)Nc1ccc(F)c(I)c1F.Nc1ccccc1-c1ncnc2c1ncn2C1CCCCO1>>CCCS(=O)(=O)Nc1ccc(F)c(Nc2ccccc2-c2ncnc3c2ncn3C2CCCCO2)c1F,,C1CCOC1,O,N#N,O=C([O-])[O-].[K+].[K+],test
US06262045B1,COC(=O)c1c(C(C)=O)c2c(Br)cccc2n1C.NNc1ccccc1>>Cc1nn(-c2ccccc2)c(=O)c2c1c1c(Br)cccc1n2C,,CC(=O)O,,,,test
US20160096834A1,COc1ccc(-c2nc3c(-c4ccc(CN)c(F)c4)ccnc3[nH]2)cc1.O=C(Cl)c1ccc(C2CC2)cc1>>COc1ccc(-c2nc3c(-c4ccc(CNC(=O)c5ccc(C6CC6)cc5)c(F)c4)ccnc3[nH]2)cc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US04214890,COC(=O)COc1cc(C)nc(N)n1.O=C=NS(=O)(=O)c1cccs1>>COC(=O)COc1cc(C)nc(NC(=O)NS(=O)(=O)c2cccs2)n1,,ClCCl,,[Na+].[OH-],,test
US20070082952A1,COC(=O)[C@@H](N)Cc1ccc(-c2ccccc2)cc1.O=C(O)c1ccc(Br)cc1>>COC(=O)[C@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)c1cccc(Br)c1,,O,,CCN(C(C)C)C(C)C,CN(C)C=O,test
US20140080798A1,C=O.NC(=O)Cc1ccccc1CCc1nc(Nc2cnn(C3CCNCC3)c2)ncc1C(F)(F)F>>CN1CCC(n2cc(Nc3ncc(C(F)(F)F)c(CCc4ccccc4CC(N)=O)n3)cn2)CC1,,CO,,,,test
US20060022176A1,COc1ccccc1.O=C(Cl)c1ccc(F)cc1>>COc1ccc(C(=O)c2ccc(F)cc2)cc1,,ClCCl,O,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20060035869A1,NC1CCCCCCC1.O=C=NC1CCCCC1>>O=C(NC1CCCCCCC1)NC1CCCCC1,,CCCCCC,,,,test
US20060154930A1,O=C1NN=CCC1C(F)(F)F>>O=c1[nH]nccc1C(F)(F)F,,CC(=O)O,,BrBr,,test
US20110190341A1,CC(C)(C)[Si](C)(C)OC1C[C@@H]2C[C@H]1C[C@@]2(C#N)c1ccccc1.CC[Mg]Br>>CCC(N)[C@@]1(c2ccccc2)C[C@@H]2C[C@H]1CC2O,,C1CCOC1,Cc1ccccc1,CCO,[BH4-].[Na+],test
US20070219235A1,CN1CCN(c2cc(N)c(N)cc2C(=O)Nc2ccc3cn[nH]c3c2)CC1.N#CBr>>CN1CCN(c2cc3[nH]c(N)nc3cc2C(=O)Nc2ccc3cn[nH]c3c2)CC1,,CCO,CCOCC,,,test
US20100184766A1,CC1(C)CCC(=O)CC1.COC(=O)OC>>COC(=O)C1CC(C)(C)CCC1=O,,C1CCOC1,CCCCCC,Cl,[H-].[Na+],test
US20120258963A1,CCOC(=O)C1CCc2sc(F)nc21>>O=C(O)C1CCc2sc(F)nc21,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20120252805A1,COc1cccc(-c2c(C)sc3nc(C)cc(N)c23)c1.O=S(=O)(Cl)c1ccccc1>>COc1cccc(-c2c(C)sc3nc(C)cc(NS(=O)(=O)c4ccccc4)c23)c1,,C1CCOC1,O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US06030983,CC(=O)NC1=CC(=O)c2ccc(C=O)nc2C1=O.CN[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCCN(C)C>>COC(=O)c1cc2c([nH]c3ccccc32)c(-c2ccc3c(n2)C(=O)C(NC(C)=O)=CC3=O)n1,,COc1ccccc1,,,,test
US05510366,C=CCI.Cc1ccc(O)c2c1NC(=O)C2(C)C>>C=CCOc1ccc(C)c2c1C(C)(C)C(=O)N2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080312282A1,CCN1CCC(O)(c2ncc(-c3ccc(NC(=O)OC(C)(C)C)c(F)c3)s2)CC1>>CCN1CCC(O)(c2ncc(-c3ccc(N)c(F)c3)s2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080132480A1,CC(C)(C)OC(=O)CBr.O=C(c1ccc(-c2cc(Cl)ccc2O)cc1Cl)N1CCCC1>>O=C(O)COc1ccc(Cl)cc1-c1ccc(C(=O)N2CCCC2)c(Cl)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130296320A1,CC1(C)OB(c2ccc(C#N)c(NC3CCC(O)CC3)c2)OC1(C)C.Clc1nccc2c(Br)cccc12>>N#Cc1ccc(-c2nccc3c(Br)cccc23)cc1NC1CCC(O)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20090203750A1,CCOC(=O)[C@@H]1C[C@H]1c1cccc(-c2ccc(Cl)cc2)c1>>O=C(O)[C@@H]1C[C@H]1c1cccc(-c2ccc(Cl)cc2)c1,,CO,,O,[K+].[OH-],test
US20050043388A1,COC(=O)c1ccc(C(=O)Nc2cccc(S(=O)(=O)C(F)(F)F)c2)cc1.NN>>NNC(=O)c1ccc(C(=O)Nc2cccc(S(=O)(=O)C(F)(F)F)c2)cc1,,CCO,,O,,test
US20150361123A1,C=Cc1ccc(F)cc1.Oc1ccc(I)cc1>>Oc1ccc(/C=C/c2ccc(F)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20130041007A1,Cc1ccc(S(=O)(=O)n2c3c(c4cc(Cl)c(Cl)cc42)CCCC3=O)cc1.O=S(=O)(NF)c1ccccc1>>Cc1ccc(S(=O)(=O)n2c3c(c4cc(Cl)c(Cl)cc42)CCC(F)C3=O)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US06380387B1,CC(=O)OC(C)OC(=O)[C@H](Cc1ccc(-c2c(C)n(C)c(=O)n(C)c2=O)cc1)NC(=O)OC(C)(C)C.Cl>>CC(=O)OC(C)OC(=O)[C@@H](N)Cc1ccc(-c2c(C)n(C)c(=O)n(C)c2=O)cc1.Cl,,CCOCC,ClCCl,C1COCCO1,,test
US04025528,CCOC(=O)c1cnc(Br)s1.Oc1ccccc1>>CCOC(=O)c1cnc(Oc2ccccc2)s1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160168119A1,CCOC(=O)/C=C/c1ccc(Cl)cc1Cn1nnc(C)n1>>Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)O)n1,,CCO,,[Na+].[OH-],,test
US04428955,Cc1cc(=O)c2ccc(O)cc2o1.O=C(NC1CCN(CCCCl)CC1)c1ccccc1>>Cc1cc(=O)c2ccc(OCCCN3CCC(NC(=O)c4ccccc4)CC3)cc2o1,,CC(C)O,,[Na],,test
US20100249385A1,CCO.Fc1c(F)c(F)c2c(F)c(F)c(F)c(F)c2c1F.NN>>NNC1=C(F)c2c(F)c(F)c(F)c(F)c2CC(F)=C1F,,O,,,,test
US20010003782A1,Cc1ccccc1S(=O)(=O)OCCC[C@@H](C)[C@H]1CC=C2C3=C(CC[C@@]21C)[C@@]1(C)CCC(O)C(C)(C)[C@@H]1CC3>>CCC[C@@H](C)[C@H]1CC=C2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](O)C(C)(C)C1CC3,,CCOCC,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US04587341,CC(=O)CC(=O)Nc1cccc(Br)c1>>Cc1cc(O)nc2cc(Br)ccc12,,O=S(=O)(O)O,,,,test
US20120035214A1,CC(=O)NCCc1ccccc1-c1onc([C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(O)c2ccc(COCC(F)(F)COC(C)C)cc2)c1Br.Cl>>CC(=O)NCCc1ccccc1-c1onc([C@H]2C[NH2+]CC[C@]2(O)c2ccc(COCC(F)(F)COC(C)C)cc2)c1Br.[Cl-],,ClCCl,,C1COCCO1,,test
US04473395,CCOC(=O)c1cc(-c2ccc([N+](=O)[O-])cc2)cnc1C>>CCOC(=O)c1cc(-c2ccc(N)cc2)cnc1C,[Fe],CCO,,Cl,O,test
US20040077877A1,CC(=O)N1CCN(CC(=O)NN)CC1.CCOC(N)c1ccc2[nH]nc(-c3ccc(F)cc3)c2c1>>CC(=O)N1CCN(Cc2nnc(-c3ccc4[nH]nc(-c5ccc(F)cc5)c4c3)[nH]2)CC1,,CO,,Cl,C[O-].[Na+],test
US07566712B2,CC1CCCN1.C[C@@H]1CN(c2ncccc2Cl)CCN1c1cc(-c2ccc(F)c(Cl)c2)nc(S(=O)(=O)Cc2ccccc2)n1>>CC1CCCN1c1nc(-c2ccc(F)c(Cl)c2)cc(N2CCN(c3ncccc3Cl)C[C@H]2C)n1,,C1COCCO1,,,,test
US04187303,CN1C(=O)Cc2cscc2S1(=O)=O.O=C=Nc1ccc(Br)cc1>>CN1C(O)=C(C(=O)Nc2ccc(Br)cc2)c2cscc2S1(=O)=O,,CS(C)=O,,CCN(CC)CC,Cl,test
US05665747,Brc1nccs1.CC(=O)c1nccs1>>CC(O)(c1nccs1)c1nccs1,,CCOCC,,[Li]CCCC,O=C([O-])O.[Na+],test
US20150174103A1,CN(C(=O)n1cnc(-c2cccc([N+](=O)[O-])c2)c1)C1CCCC1>>CN(C(=O)n1cnc(-c2cccc(N)c2)c1)C1CCCC1,[Pd],CCO,,CCOC(C)=O,,test
US20040048908A1,COC(=O)CCc1cnoc1-c1ccc(SC)cc1>>CSc1ccc(-c2oncc2CCCO)cc1,,C1CCOC1,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US04419352,CCOC(=O)c1cc(=O)c2c(OC)cc3c(Cl)cc(C(=O)OC)nc3c2o1>>COc1cc2c(Cl)cc(C(=O)O)nc2c2oc(C(=O)O)cc(=O)c12,,CC(=O)O,,Cl,,test
US20110263567A1,COc1cccc(C=O)c1C.NO>>COc1cccc(C=NO)c1C,,CCO,O,Cl,,test
US20160257668A1,CC(C)(C)OC(=O)c1ccc(N)cc1.O=C(O)c1ncc(F)cc1Br>>CC(C)(C)OC(=O)c1ccc(NC(=O)c2ncc(F)cc2Br)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06969776B2,CC(C)OC(=O)C(F)(OC(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F.O=C(OC(C(F)(F)F)C(F)(F)F)C(F)(OC(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F>>O=C(OC(F)(C(F)(F)F)C(F)(F)F)C(F)(OC(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F,,c1ccccc1,,,,test
US20110118245A1,COc1cc(O)c2c(=O)n(COC(=O)C(C)(C)C)cnc2c1.OC1CCOCC1>>COc1cc(OC2CCOCC2)c2c(=O)[nH]cnc2c1,,ClCCl,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160024060A1,COCc1ccc(C(C)=O)c2sc(C(=O)Nc3cc(CN4CC[C@@H](O)C4)c4ccccc4n3)c(C)c12.Cc1ccc(S(=O)(=O)O)cc1>>COCc1ccc(C(C)=O)c2sc(C(=O)Nc3cc(CN4CC[C@@H](O)C4)c4ccccc4n3)c(C)c12.Cc1ccc(S(=O)(=O)O)cc1,,O,,CO,,test
US20040034050A1,CCOC(=O)CBr.Oc1ccnc2ccccc12>>O=C(O)COc1ccnc2ccccc12,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040229874A1,CC(C)(C)OC(=O)N1CCN(c2ccccc2Br)CC1.O=Cc1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)N1CCN(c2ccccc2-c2ccc(C=O)cc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US20120202785A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.C[C@H](Nc1ncnc(N)c1C#N)c1nc2ccc(F)c(Br)c2n1C>>C[C@H](Nc1ncnc(N)c1C#N)c1nc2ccc(F)c(-c3cn[nH]c3)c2n1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100273806A1,CCOC(=O)CC1CCc2c1[nH]c1ccc(C(=N)NO)cc21.N#Cc1cc(C(=O)O)ccc1OC1CCCC1>>CCOC(=O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4ccc(OC5CCCC5)c(C#N)c4)n3)cc21,CN(C)C=O,O,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US06277862B1,CC[C@H](NC(=O)c1c(O)c(-c2ccccc2)nc2ccccc12)c1ccccc1.O=C1c2ccccc2C(=O)N1CCBr>>CC[C@H](NC(=O)c1c(OCCN2C(=O)c3ccccc3C2=O)c(-c2ccccc2)nc2ccccc12)c1ccccc1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20020065401A1,CC(C)(C)c1ccc(O)c(C(C)(C)C)c1>>CC(C)(C)C1CCC(=O)C(C(C)(C)C)C1,[Rh],CCO,,,,test
US06037362,O=C(NCCBr)OCc1ccccc1.Oc1ccc2c(c1)sc1ccccc12>>O=C(NCCOc1ccc2c(c1)sc1ccccc12)OCc1ccccc1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090275578A1,Cc1cc(F)ccc1C(=O)O.ClCCl>>COC(=O)c1ccc(F)cc1C,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20090280416A1,C=COCCCCCBr.CCOC(=O)c1ccc(O)cc1>>C=COCCCCCOc1ccc(C(=O)O)cc1,,O,,CC(=O)N(C)C,O=C([O-])[O-].[K+].[K+],test
US20060205737A1,CC(Nc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1C(=O)C(F)(F)F)c1cc(Cl)cc(Cl)c1.Cl>>CC(Nc1cc(N2CCNCC2)ccc1C(=O)C(F)(F)F)c1cc(Cl)cc(Cl)c1.Cl,,CCOCC,ClCCl,,,test
US20130274260A1,CI.COC(=O)c1ccc(Nc2cccc(F)c2)cc1>>CN(c1ccc(C(=O)O)cc1)c1cccc(F)c1,,C1CCOC1,O,Cl,[H-].[Na+],test
US20160145206A1,N#Cc1cc(Cl)ccc1Br.OB(O)c1ccccc1>>N#Cc1cc(Cl)ccc1-c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US05631257,Clc1nc2ccccc2o1.OCCN1CCCNCC1>>OCCN1CCCN(c2nc3ccccc3o2)CC1,,CN(C)C=O,,,,test
US20100056511A1,CC(C)(C)[Si](C)(C)OCCN(CCO[Si](C)(C)C(C)(C)C)c1cccc(N2CCN(c3ccc(NC(=O)C(=O)c4c(-c5ccccc5)cc5ccccn45)cc3)CC2)n1>>O=C(Nc1ccc(N2CCN(c3cccc(N(CCO)CCO)n3)CC2)cc1)C(=O)c1c(-c2ccccc2)cc2ccccn12,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120184542A1,CC(C)(C)OC(=O)NCCC(NC(=O)c1ccc(Cl)c(NC(=O)c2cc3cnc(S(C)(=O)=O)nc3[nH]c2=O)c1)c1ccccc1.CN1CCN(CCCN)CC1>>CN1CCN(CCCNc2ncc3cc(C(=O)Nc4cc(C(=O)NC(CCNC(=O)OC(C)(C)C)c5ccccc5)ccc4Cl)c(=O)[nH]c3n2)CC1,,O,,CN(C)C=O,,test
US03980788,CN(C)C1CCCN(Cc2ccccc2)C1>>CN(C)C1CCCNC1,[Pd],CO,,[H][H],,test
US06410592B1,COc1cc2c(cc1OC)C(=O)CCC2>>O=C1CCCc2cc(O)c(O)cc21,,O,,Br,,test
US20090163512A1,CC(=O)OC(C)=O.CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(Cl)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)NS(C)(=O)=O>>CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(Cl)ccc2C)C12C(=O)N(C(C)=O)c1cc(Cl)ccc12)C(=O)NS(C)(=O)=O,CN(C)c1ccncc1,ClCCl,,,,test
US20150266857A1,C1CNCCN1.C=CS(=O)(=O)NCc1nc2ccc(-c3c[nH]c4cc(F)ccc34)cc2o1>>O=S(=O)(CCN1CCNCC1)NCc1nc2ccc(-c3c[nH]c4cc(F)ccc34)cc2o1,,C1CCOC1,CC#N,[Cl-].[NH4+],,test
US20090012118A1,Cc1ccc(CC2CCNCC2)cc1.O=C(O)c1cc(=O)c2cc(O)ccc2[nH]1>>Cc1ccc(CC2CCN(C(=O)c3cc(=O)c4cc(O)ccc4[nH]3)CC2)cc1,,CCOCC,,,,test
US20070112068A1,CC(Br)CCBr.N#CC(C#N)CC(F)(F)C(F)(F)C(F)(F)C(F)F>>CC(Br)CCC(C#N)(C#N)CC(F)(F)C(F)(F)C(F)(F)C(F)F,,CS(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20020193382A1,CC(C)(C)OC(=O)N1C=CN(Cc2ccc(-n3ccnc3)cc2)C(=O)[C@@H]1COCc1ccccc1>>CC(C)(C)OC(=O)N1CCN(Cc2ccc(-n3ccnc3)cc2)C(=O)[C@@H]1COCc1ccccc1,[Pd],CCO,,,,test
US20080039457A1,CI.NNC(N)=S.O=C(O)C(=O)c1ccccc1>>CSc1nnc(-c2ccccc2)c(=O)[nH]1,,CO,O,[K+].[OH-],,test
US20100137278A1,CC1(C)OB(C2=CCC(F)(F)CC2)OC1(C)C.O=C(c1ccc(Oc2nccnc2Cl)cc1)c1nc2ccccc2[nH]1>>O=C(c1ccc(Oc2nccnc2C2=CCC(F)(F)CC2)cc1)c1nc2ccccc2[nH]1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20110053931A1,COc1cc2c(Oc3ccc([N+](=O)[O-])cn3)ccnc2cc1OCc1ccccc1>>COc1cc2c(Oc3ccc([N+](=O)[O-])cn3)ccnc2cc1O,,CC(=O)O,CCOCC,Br,,test
US20110190278A1,CC(C)N(C(=O)c1ccc2c(c1)N(CCN)C(=O)C2(C)C)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1.O=C(O)C(F)F>>CC(C)N(C(=O)c1ccc2c(c1)N(CCNC(=O)C(F)F)C(=O)C2(C)C)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1,,CCN(CC)CC,ClC(Cl)Cl,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20090247551A1,CNCc1cnc(Cl)c(F)c1.O=C1COC(=O)C1>>CN(Cc1cnc(Cl)c(F)c1)C1=CC(=O)OC1,,CC(=O)O,,,,test
US20080255123A1,CC(C)=O.COc1ccc(Cl)cc1C(=O)/C=C1\SC=C(C)N1CC1CCC1>>COc1ccc(Cl)cc1C(=O)/C=C1\SC(C(C)(C)O)=C(C)N1CC1CCC1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US05922404,COP([O-])OC.O=CC(Cl)(Cl)Cl>>COP(=O)(OC)C(O)C(Cl)(Cl)Cl,,c1ccccc1,,,,test
US20070197542A1,CS(=O)(=O)Cl.c1ccc(COc2ccc(N3CCNCC3)nc2)cc1>>CS(=O)(=O)N1CCN(c2ccc(OCc3ccccc3)cn2)CC1,,ClCCl,,CCN(CC)CC,,test
US20080319074A1,CCCCCCC(C=O)c1ccc(C(=O)OC)cc1>>CCCCCCC(CO)c1ccc(C(=O)OC)cc1,,CCO,,[BH4-].[Na+],,test
US20090149475A1,NCc1ccccn1.O=C(N=C=S)c1ccccc1>>NC(=S)NCc1ccccn1,,ClCCl,,,,test
US20160185775A1,COc1ccc(F)c(CO)c1F.O=S(Cl)Cl>>COc1ccc(F)c(CCl)c1F,,O=S(Cl)Cl,,ClCCl,,test
US20050090472A1,COC(=O)c1ccc(OCC(C)C)c([N+](=O)[O-])c1>>CC(C)COc1ccc(C(=O)O)cc1[N+](=O)[O-],,C1CCOC1,CO,[Na+].[OH-],,test
US20080021217A1,Br.CC(C)(C)OC(=O)NCc1nc(-c2ccncc2)n[nH]1>>Br.NCc1nc(-c2ccncc2)n[nH]1,,CC(=O)O,,,,test
US20070099990A1,CC[Mg]Br.Cc1c(C=O)c2c(c(C)c1NC(=O)CC(C)(C)C)C(c1ccc(C(C)C)cc1)CS2>>CCCc1c(C)c(NC(=O)CC(C)(C)C)c(C)c2c1SCC2c1ccc(C(C)C)cc1,,CCCCCC,CCOC(C)=O,,,test
US20150297586A1,ClCCCCn1nnc2ccccc21.c1coc(N2CCNCC2)c1>>c1coc(N2CCN(CCCCn3nnc4ccccc43)CC2)c1,,CC#N,,CCN(C(C)C)C(C)C,[I-].[K+],test
US20070124152A1,CCOC(=O)CC(=O)Cl.CCOC(=O)c1ncc(Cc2ccc(F)cc2)cc1NC=C(C)C>>CCOC(=O)CC(=O)N(CC(C)C)c1cc(Cc2ccc(F)cc2)cnc1C(=O)OCC,,ClCCCl,,ClCCl,O=C([O-])O.[Na+],test
US20160257652A1,CC1(C)CO1.Cc1cc(-c2nc[nH]n2)cc(C)c1Br>>Cc1cc(-c2ncn(CC(C)(C)O)n2)cc(C)c1Br,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20140309210A1,C1CCOC1.CC(=O)c1cccc(C#N)c1>>C=C(C)c1cccc(C#N)c1,,C1CCOC1,,O,[Li]CCCC,test
US20140107340A1,CCOC(=O)CP(=O)(OCC)OCC.O=C(c1ccccc1)c1ccnnc1>>CCOC(=O)/C=C(\c1ccccc1)c1ccnnc1,,C1CCOC1,,[H-].[Na+],,test
US20040102450A1,COCC1C(=O)N(Cc2ccc3c(N)ncnc3c2)CCN1C(=O)OCc1ccccc1.O=C(O)c1nc2ccc(Cl)cc2[nH]1>>COC[C@H]1C(=O)N(Cc2ccc3c(N)ncnc3c2)CCN1C(=O)c1nc2ccc(Cl)cc2[nH]1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20100137299A1,O=S(Cl)Cl.OCc1ncc(F)cc1F>>Cl.Fc1cnc(CCl)c(F)c1,CN(C)C=O,ClCCl,,,,test
US20100075948A1,CC(C)(C)C[C@@H]1N[C@@H](C(=O)N[C@@H]2CC[C@@H](N)CC2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F.NS(N)(=O)=O>>CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCN(S(N)(=O)=O)CC2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F,,C1CCOC1,,O=C(O)C(F)(F)F,,test
US20100310512A1,COC(=O)NC(C(=O)N1CCCC1c1nc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)c[nH]1)C(C)C.COC(=O)NC(C(=O)N1CN(CC(F)(F)F)CC1c1nc(-c2ccc(Br)cc2)c[nH]1)C(C)C>>COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(-c3ccc(-c4cnc(C5CN(CC(F)(F)F)CN5C(=O)C(NC(=O)OC)C(C)C)[nH]4)cc3)cc2)[nH]1)C(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US05064839,C=C1CC(=O)O1.OCCOCCN1CCC(c2ccccc2)(c2ccccc2)CC1>>CC(=O)CC(=O)OCCOCCN1CCC(c2ccccc2)(c2ccccc2)CC1,,CC(C)=O,ClCCl,,,test
US04474754,CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)NNC(=O)OC(C)(C)C>>CC(C)C[C@H](N)C(=O)N[C@@H](CCC(N)=O)C(=O)NNC(=O)OC(C)(C)C,[Pd],CO,,[H][H],,test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)[nH]c1=O.O=P(Cl)(Cl)Cl>>CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1Cl,,Cc1ccccc1,,CN(C)c1ccccc1,,test
US20030207914A1,CC(C)(C)c1ccnc(N)c1.O=C=Nc1cccc(Cl)c1Cl>>CC(C)(C)c1ccnc(NC(=O)Nc2cccc(Cl)c2Cl)c1,,CCOC(C)=O,Cc1ccccc1,,,test
US20130274244A1,O=[N+]([O-])c1cccc2c1cnn2Cc1ccc(F)cc1F>>Nc1cccc2c1cnn2Cc1ccc(F)cc1F,[Fe],CCO,O,[Cl-].[NH4+],,test
US06515011B2,CS(=O)(=O)Cl.C[C@](O)(C(=O)N1CCC[C@H]1C(=O)NCc1cc(Cl)ccc1CCN)c1ccccc1>>C[C@](O)(C(=O)N1CCC[C@H]1C(=O)NCc1cc(Cl)ccc1CCNS(C)(=O)=O)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20040077726A1,CNc1ccccc1.COC(=O)C=Cc1cccc(S(=O)(=O)Cl)c1>>COC(=O)C=Cc1cccc(S(=O)(=O)N(C)c2ccccc2)c1,,ClCCl,,c1ccncc1,,test
US20060014948A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.Cc1ccc(C[C@@H]2CNCCN2C(=O)OC(C)(C)C)cc1O>>Cc1ccc(C[C@@H]2CNCCN2C(=O)OC(C)(C)C)cc1O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US20130344030A1,C=CC1(C(=O)OCc2ccccc2)COC(C)(C)CO1>>C=CC1(C(=O)O)COC(C)(C)CO1,,C1CCOC1,O,[Li+].[OH-],,test
US20100216836A1,CS(=O)(=O)OC[C@H]1COc2ccc(F)cc2O1.C[C@]1(COCCOC2CCCCO2)CCCNC1>>CC1(COCCO[C@H]2CCCCO2)CCCN(C[C@H]2COc3ccc(F)cc3O2)C1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050026916A1,FC(F)(F)Oc1ccc(CCl)cc1.S=C1N[C@@H](c2ccccc2)[C@@H](c2ccccc2)N1>>Cl.FC(F)(F)Oc1ccc(CSC2=N[C@@H](c3ccccc3)[C@@H](c3ccccc3)N2)cc1,,CCO,,,,test
US20060025438A1,CC(C)(C)OC(=O)NCC(=O)NCc1cccnc1>>NCC(=O)NCc1cccnc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20140018319A1,CCNc1nc(Nc2cc(C#N)cc(C3CNC3)c2Cl)nn2c(C#N)cnc12.C[C@H]1CO1>>CCNc1nc(Nc2cc(C#N)cc(C3CN(C[C@H](C)O)C3)c2Cl)nn2c(C#N)cnc12,,CN1CCCC1=O,CO,,,test
US20100137317A1,COc1ccc(C2=C(c3ccc(O)cc3)OC(C)(C)C2=O)cc1.ClCc1ccc2ccccc2n1>>COc1ccc(C2=C(c3ccc(OCc4ccc5ccccc5n4)cc3)OC(C)(C)C2=O)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090156582A1,COC(=O)c1n[nH]cc1[N+](=O)[O-].ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)c1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1[N+](=O)[O-],,CN(C)C=O,O,CCN(CC)CC,,test
US20080275067A1,Cc1cccc2nc(CN)n(-c3ccccc3)c(=O)c12.N=C(c1ccccc1)c1ccccc1>>Cc1cccc2nc(CN=C(c3ccccc3)c3ccccc3)n(-c3ccccc3)c(=O)c12,,ClCCCl,,,,test
US20130079306A1,CCO.Cc1cc(C(=O)O)ccc1N>>CCOC(=O)c1ccc(N)c(C)c1,,O=S(=O)(O)O,,,,test
US20080114005A1,CCCc1nn(C)c2c(=O)[nH]c(C(=O)OCC)nc12>>CCCc1nn(C)c2c(=O)[nH]cnc12,,CO,O,[Li+].[OH-],,test
US20050049245A1,CN.Cc1cc(C(=O)CBr)c(C)o1>>CNCC(O)c1cc(C)oc1C,,CO,O,[BH4-].[Na+],,test
US04539422,CCOC(=O)Cn1nnnc1C(=O)OCC(C)C>>O=C(O)Cn1cnnn1,,O,,Cl,,test
US20030109523A1,CCOC(=O)CCC1Cc2cc(OC)ccc2NC1=O>>CCOC(=O)CCC1Cc2cc(O)ccc2NC1=O,,CCO,,,,test
US03979390,O=C(c1ccccc1)C(F)CC(F)N1CCC(O)(c2ccc(Cl)cc2)CC1.OC1(c2ccc(Cl)cc2)CCNCC1>>O=C(c1ccccc1)C(F)CC(N1CCC(O)(c2ccc(Cl)cc2)CC1)N1CCC(O)(c2ccc(Cl)cc2)CC1,,O,,CS(C)=O,,test
US20080058521A1,COc1ccc(B(O)O)cc1C=O.Cc1cc(Cl)ccn1>>COc1ccc(-c2ccnc(C)c2)cc1C=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US04703046,CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(COC(=O)NC(=O)C(Cl)(Cl)Cl)CS[C@H]12)c1nc(NC=O)sc1Br>>CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(COC(N)=O)CS[C@H]12)c1nc(NC=O)sc1Br,,CO,,O=C([O-])O.[Na+],,test
US04694004,Nc1ccncn1.O=C(NN1CC=CCC1)Oc1ccccc1>>O=C(Nc1ccncn1)NN1CC=CCC1,CN(C)c1ccncc1,ClCCCl,,,,test
US20150175604A1,BrCCc1ccccc1.Cc1nnc2ccc3[nH]ccc3n12>>Cc1nnc2ccc3c(ccn3C(C)c3ccccc3)n12,,CC#N,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100130738A1,CI.COC(=O)C(C)C(=O)c1ccc(OC)c2nc(C(F)(F)F)sc12>>COC(=O)C(C)(C)C(=O)c1ccc(OC)c2nc(C(F)(F)F)sc12,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20120165324A1,O=C(CCl)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1.Oc1ccc(F)cc1F>>O=C(COc1ccc(F)cc1F)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20130230542A1,CO.O=C(O)CCCc1ccc(N(CCCl)CCCl)cc1>>COC(=O)CCCc1ccc(N(CCCl)CCCl)cc1,,CO,,CCN(C(C)C)C(C)C,,test
US20140249143A1,BrCc1ccccc1.FC(F)(F)c1cc(C(F)(F)F)c2ccc3cc(-c4nnco4)[nH]c3c2n1>>FC(F)(F)c1cc(C(F)(F)F)c2ccc3cc(-c4nnco4)n(Cc4ccccc4)c3c2n1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US06464731B1,CNc1ccc(N(C)CC[n+]2ccn(C)c2)cc1[N+](=O)[O-].[Cl-]>>CNc1ccc(N(C)CCCl)cc1[N+](=O)[O-].Cn1ccnc1,,Cc1ccccc1,,O,,test
US20030013769A1,CBr.CN(C)C(C)(C)CC(C)(C)C>>CC(C)(C)CC(C)(C)[N+](C)(C)C.[Br-],,ClCCl,,,,test
US20060035951A1,O=C(O)c1ccc(Nc2cccc(F)c2)c([N+](=O)[O-])c1>>Nc1cc(C(=O)O)ccc1Nc1cccc(F)c1,[Pd],C1CCOC1,,,,test
US20150112063A1,CI.Cn1ncc(-c2nn[nH]n2)c1Br>>Cn1nnc(-c2cnn(C)c2Br)n1,,CC#N,,[K+].[OH-],,test
US07196104B2,CCOC(=O)c1csc(Oc2ccccc2)n1>>O=C(O)c1csc(Oc2ccccc2)n1,,CO,O,C1CCOC1,,test
US20150322056A1,COc1cc(-n2ccc(N3CCO[C@H]([C@@](C)(O)C(=O)Nc4cnc5c(N6C(=O)c7ccccc7C6=O)noc5c4)C3=O)n2)ccn1>>COc1cc(-n2ccc(N3CCO[C@H]([C@@](C)(O)C(=O)Nc4cnc5c(N)noc5c4)C3=O)n2)ccn1,,CO,ClCCl,NN,,test
US05296495,COc1ccc(OCC#N)c(C=O)c1.S>>COc1ccc2oc(C(N)=S)cc2c1,,CN(C)C=O,,Cl,[Na],test
US20020006937A1,O=C(NCc1ccc(Cl)cc1)c1cnc2sc(C#CCO)cc2c1O.O=C(O)CBr>>O=C(O)Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(C#CCO)sc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020132796A1,CC1(C)CC(C)(C)c2cc(Br)ccc2O1.CCOCC>>CC1(C)CC(C)(C)c2cc(Br)cc(C=O)c2O1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20140024650A1,CC(=O)O.CCS(=O)(=O)N[C@@H]1CCN(Cc2ccccc2)C[C@H]1COc1ccc(CCC#N)cc1>>CCS(=O)(=O)N[C@@H]1CCN(C(C)=O)C[C@H]1COc1ccc(CCC#N)cc1,[Pd],,,,,test
US05391817,CCCCCOc1ccc(C=O)cc1OC(C)=O>>CCCCCOc1ccc(CO)cc1OC(C)=O,,CO,,Cl,[BH4-].[Na+],test
US20130156732A1,C[C@H]1CC[C@@H](C(=O)O)N1C(=O)OC(C)(C)C.C[C@H]1CC[C@@H](C(=O)OCC(=O)c2ccc3c(c2)COc2cc4c(cc2-3)CCC(Br)C4=O)N1C(=O)OC(C)(C)C>>C[C@H]1CC[C@@H](C(=O)OCC(=O)c2ccc3c(c2)COc2cc4c(cc2-3)CCC(OC(=O)[C@@H]2CC[C@H](C)N2C(=O)OC(C)(C)C)C4=O)N1C(=O)OC(C)(C)C,,CC(C)=O,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110098296A1,COC(=O)c1ccc(F)c(N)c1.O=C(Cl)c1c(F)cccc1F>>COC(=O)c1ccc(F)c(NC(=O)c2c(F)cccc2F)c1,,ClCCl,,,,test
US20080255060A1,CCCOCCNC(=O)OC(C)(C)C.CCOC(=O)c1cn(CC)c2ccc(I)cc2c1=O>>CCOC(=O)c1cn(CC)c2ccc(C#CCOCCNC(=O)OC(C)(C)C)cc2c1=O,I[Cu]I,CC#N,CCN(CC)CC,,,test
US20020055631A1,BrCc1ccccc1.O=C(O)c1ccc(F)cc1>>O=C(OCc1ccccc1)c1ccc(F)cc1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070049603A1,CCOC(=O)c1oc2cnccc2c1Nc1ccc2c(O[Si](C)(C)C(C)(C)C)cccc2c1.NCCN>>CC(C)(C)[Si](C)(C)Oc1cccc2cc(Nc3c(C(=O)NCCN)oc4cnccc34)ccc12,,ClCCl,,N#N,,test
US20110092495A1,COc1ccc2c(c1)N(CCN1CCC(NC(=O)OC(C)(C)C)CC1)C(=O)OC2>>COc1ccc2c(c1)N(CCN1CCC(N)CC1)C(=O)OC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100249139A1,COC(=O)c1ccc(Oc2ccc(Cl)c(C(C)C(O)(c3ccnc(Cl)c3)C(F)(F)F)c2)cc1OC>>COc1cc(Oc2ccc(Cl)c(C(C)C(O)(c3ccnc(Cl)c3)C(F)(F)F)c2)ccc1C(=O)O,,C1CCOC1,CO,[Li+].[OH-],,test
US20110166146A1,Cn1ccnc1C(O)c1c(-c2ccc(F)cc2)nc2ccc(F)cn12>>Cn1ccnc1Cc1c(-c2ccc(F)cc2)nc2ccc(F)cn12,,ClCCl,,,,test
US20040058903A1,CC(=O)OC(C)=O.Nc1cccc(C(=O)NCc2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2)n1>>CC(=O)Nc1cccc(C(=O)NCc2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2)n1,,CCOC(C)=O,,O,,test
US20160222014A1,CC(C)(C)OC(=O)NC1CCN(c2ccc([N+](=O)[O-])cc2)CC1.CI>>CN(C(=O)OC(C)(C)C)C1CCN(c2ccc([N+](=O)[O-])cc2)CC1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20020137152A1,C#CCC(O)C=Cc1ccccc1.CC(=O)OC(C)=O>>C#CCC(C=Cc1ccccc1)OC(C)=O,CN(C)c1ccncc1,CCOCC,,c1ccncc1,,test
US05070086,Clc1ccccc1CC1=NCCN1.O=C(Cl)c1cccnc1Cl>>O=C(c1cccnc1Cl)N1CCN=C1Cc1ccccc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05547967,CC(=O)OC(C)=O.CN(CCOc1cc(-c2ccc(O)cc2)nn1C)CCc1ccc(Cl)cc1>>CC(=O)Oc1ccc(-c2cc(OCCN(C)CCc3ccc(Cl)cc3)n(C)n2)cc1,,CC(C)O,ClCCl,Cl,c1ccncc1,test
US20100273837A1,CCOC(=O)C#N.O=c1oc(-c2ccc(OCc3ccccc3)cc2)ns1>>CCOC(=O)c1nc(-c2ccc(OCc3ccccc3)cc2)ns1,,Clc1ccccc1Cl,,,,test
US20110269956A1,C[C@H]1C[C@@H](c2nc(-c3ccc(-c4ccc5cc(-c6c[nH]c([C@@H]7C[C@H](C)CN7C(=O)OC(C)(C)C)n6)ccc5c4)cc3)c[nH]2)N(C(=O)OC(C)(C)C)C1>>C[C@@H]1CN[C@H](c2nc(-c3ccc(-c4ccc5cc(-c6c[nH]c([C@@H]7C[C@H](C)CN7)n6)ccc5c4)cc3)c[nH]2)C1,,C1COCCO1,CO,Cl,,test
US20040110742A1,CS(=O)(=O)Cl.OC[C@H]1CCCN1CCc1ccc(N2CCCC2)cc1>>Cl[C@@H]1CCCN(CCc2ccc(N3CCCC3)cc2)C1,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US03992441,COS(=O)(=O)OC.O=C(O)c1cc(S(=O)(=O)N2CCC(O)C(O)C2)ccc1Cl>>COC1CN(S(=O)(=O)c2ccc(Cl)c(C(=O)O)c2)CCC1O,,O,,[Na+].[OH-],,test
US20120028961A1,NC1CCCCC1.O=C(Cl)c1ccc(Br)cc1F>>O=C(NC1CCCCC1)c1ccc(Br)cc1F,,ClCCl,,CCN(CC)CC,,test
US20030225288A1,Brc1cccc(-c2nnn[nH]2)c1.Clc1ccccc1C(Cl)(c1ccccc1)c1ccccc1>>Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1nnnc1-c1cccc(Br)c1,,C1CCOC1,,CCN(CC)CC,,test
US20120029190A1,CCOC(=O)Cn1nc(-c2ccccn2)nc1CNC(=O)OCc1ccccc1>>O=C1Cn2nc(-c3ccccn3)nc2CN1,[Pd],CO,,,,test
US06376488B1,COC(=O)c1sc2cccnc2c1N.O=C(Cl)Cl>>COC(=O)c1sc2cccnc2c1N=C=O,,C1CCOC1,,CCN(CC)CC,Cc1ccccc1,test
US20070078184A1,CC[Si](Cl)(CC)CC.CS(=O)(=O)Nc1cc([C@@H](O)CN=[N+]=[N-])ccc1OCc1ccccc1>>CC[Si](CC)(CC)O[C@@H](CN=[N+]=[N-])c1ccc(OCc2ccccc2)c(NS(C)(=O)=O)c1,,CN(C)C=O,,O,c1c[nH]cn1,test
US05095014,CN.O=C(Cl)N1CC(Oc2ccc(Cl)cc2Cl)C1>>CNC(=O)N1CC(Oc2ccc(Cl)cc2Cl)C1,,C1CCOC1,O,,,test
US20050143443A1,CCOC(=O)c1ccc(C)[nH]1.COc1ccc(CC(=O)Cl)cc1>>CCOC(=O)c1cc(C(=O)Cc2ccc(OC)cc2)c(C)[nH]1,,ClCCCl,,,,test
US04634551,CCCCCCCCCC(=O)NCCCCCC(=O)OO.CCCCCCCCCCNC(=O)CCCCC(=O)O>>CCCCCCCCCCNC(=O)CCCCC(=O)OO,,CS(=O)(=O)O,,OO,,test
US20070191364A1,C[C@@H]1CN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC2CCC(O)(c3ccccc3)CC2)CC[C@H]1N(C(=O)N(C)C)C1CCCCC1.Cl>>C[C@@H]1CN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC2CCC(O)(c3ccccc3)CC2)CC[C@H]1N(C(=O)N(C)C)C1CCCCC1.Cl,,CCOC(C)=O,CCOCC,,,test
US20150239908A1,BrC(Br)(Br)Br.C[C@H]1SC(NC(=O)c2ccccc2)=N[C@@]2(c3ccc(F)cc3F)CO[C@@H](CO)C[C@@H]12>>C[C@H]1SC(NC(=O)c2ccccc2)=N[C@@]2(c3ccc(F)cc3F)CO[C@@H](CBr)C[C@@H]12,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04626535,CCCCC=O.CCOC(=O)Cc1nsc(NC(=O)OC(C)(C)C)n1>>CCCCC(O)C(C(=O)OCC)c1nsc(NC(=O)OC(C)(C)C)n1,,CCOC(C)=O,,,,test
US04992433,N#CCCCCCOc1ccc(C2=NCCO2)cc1>>NCCCCCCOc1ccc(C2=NCCO2)cc1,[Ni],CO,,N,[H][H],test
US05563162,COCCN.O=C(Cl)c1cccc([N+](=O)[O-])c1>>COCCNC(=O)c1cccc([N+](=O)[O-])c1,,ClCCl,,CCN(CC)CC,,test
US20080249318A1,Cc1ccc2c(c1)CC(=O)N2c1c(F)cc(F)c(F)c1F.O>>Cc1ccc(Nc2c(F)cc(F)c(F)c2F)c(CC(=O)O)c1,,O,,CCO,,test
US06399627B1,CCOC(=O)C1=C(OS(=O)(=O)C(F)(F)F)CCC1.N#Cc1cccc(B(O)O)c1>>CCOC(=O)C1=C(c2cccc(C#N)c2)CCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US04962110,CCOC(=O)CC(C)C(=O)c1ccc(N)cc1.CSc1nccc(=O)[nH]1>>CCOC(=O)CC(C)C(=O)c1ccc(Nc2nc(=O)cc[nH]2)cc1,,c1ccncc1,,,,test
US03939159,O=[N+]([O-])c1cc(Cl)c(Cl)cc1-n1cccc1>>Nc1cc(Cl)c(Cl)cc1-n1cccc1,,O,,C1CCOC1,,test
US20110195948A1,CC1(c2cccc(F)c2)CCCN1c1ccn2ncc(N)c2n1.O=C(n1ccnc1)n1ccnc1.OC1CNC1>>CC1(c2cccc(F)c2)CCCN1c1ccn2ncc(NC(=O)N3CC(O)C3)c2n1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20040122223A1,N#C[Cu].O=C(O)c1ccccc1.O=C(O)c1ccccc1.O=C(O)c1ccccc1.O=c1c2cc(Br)ccc2ccn1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>N#Cc1ccc2ccn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(=O)c2c1.O=C(O)c1ccccc1.O=C(O)c1ccccc1.O=C(O)c1ccccc1,,CN(C)C=O,,,,test
US20150376130A1,Nc1ccc(F)cc1C(=O)O.O=CCCC(F)(F)F>>O=C(O)c1cc(F)ccc1NCCCC(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05741796,CC(C)OC(=O)/N=N/C(=O)OC(C)C.OCCc1cn(Cc2ccccc2)cn1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>COC(=O)c1ccc(OCCc2cn(Cc3ccccc3)cn2)cc1,,C1CCOC1,,,,test
US20150118258A1,CC(C)(C)OC(=O)N1C[C@@H](N=[N+]=[N-])[C@H](F)C1>>CC(C)(C)OC(=O)N1C[C@@H](N)[C@H](F)C1,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140349987A1,CC(=O)c1ccc(O)cc1C(F)(F)F.CCOC=O>>O=CCC(=O)c1ccc(O)cc1C(F)(F)F,,C1CCOC1,,C[O-].[Na+],,test
US20130059853A1,BrCC1CC1.COCOc1c(Br)ccc(OC)c1O>>COCOc1c(Br)ccc(OC)c1OCC1CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110130398A1,CC(C)(C)CC1NC(C(=O)Nc2ccc(C#N)cc2)C(c2cccc(Br)c2F)C12C(=O)Nc1cc(Cl)ccc12.OO>>CC(C)(C)CC1NC(C(=O)Nc2ccc(C(N)=O)cc2)C(c2cccc(Br)c2F)C12C(=O)Nc1cc(Cl)ccc12,,CS(C)=O,,[Na+].[OH-],,test
US05459138,CC(C)N.NS(=O)(=O)c1cnccc1Cl>>CC(C)Nc1ccncc1S(N)(=O)=O,,CO,,,,test
US20080318975A1,CN(C)Cc1cnc2ccc(Cl)c(CC(N)=O)c2c1.COC(=O)C(=O)c1c[nH]c2ccccc12>>CN(C)Cc1cnc2ccc(Cl)c(C3=C(c4c[nH]c5ccccc45)C(=O)NC3=O)c2c1,,C1CCOC1,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US06287749B1,BrBr.O=C1CC=CC2=C1CCCCC2>>O=C1C2=C(C=CC1Br)CCCCC2,,CC(=O)O,,,,test
US20120264735A1,COC(=O)COC(=O)Nc1cccc(Cc2nn(-c3cnn(C)c3)ccc2=O)c1>>Cn1cc(-n2ccc(=O)c(Cc3cccc(NC(=O)OCC(=O)O)c3)n2)cn1,,C1CCOC1,,Cl,[Li+].[OH-],test
US20150368230A1,O=c1[nH]cnc2cc(O[C@H]3CCOC3)c([N+](=O)[O-])cc12>>Nc1cc2c(=O)[nH]cnc2cc1O[C@H]1CCOC1,[Fe],CCO,O,CC(=O)O,,test
US20140275152A1,BrP(Br)(c1ccccc1)(c1ccccc1)c1ccccc1.CC(C)n1nccc1C1=C(CO)CCOC1>>CC(C)n1nccc1C1=C(CBr)CCOC1,,ClCCl,,,,test
US20140256733A1,Clc1ccc2ncc(I)n2n1.OB(O)c1ccc2[nH]ccc2c1>>Clc1ccc2ncc(-c3ccc4[nH]ccc4c3)n2n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20080249093A1,COC(=O)C[C@H]1CCc2c1ccc(C#N)c2C.O>>COC(=O)C[C@H]1CCc2c1ccc(C=O)c2C,[Ni],O,c1ccncc1,CC(=O)O,,test
US20090156571A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(-c3cc(Cl)c(CC4CCN(C5CCCCC5)C4=O)c(Cl)c3)cc2)CC1>>O=C(c1ccc(-c2cc(Cl)c(CC3CCN(C4CCCCC4)C3=O)c(Cl)c2)cc1)N1CCNCC1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20090048264A1,Cc1ccc(C)c(N2CCN(C(=O)C3CN(S(=O)(=O)c4cccc(Cl)c4)CCN3C(=O)OC(C)(C)C)CC2)c1>>Cc1ccc(C)c(N2CCN(C(=O)C3CN(S(=O)(=O)c4cccc(Cl)c4)CCN3)CC2)c1,,CCO,,Cl,,test
US20100222339A1,CCC(CC)c1cc(C)nc2c(-c3cnc(COC)s3)c(C)nn12.O=C1CCC(=O)N1Cl>>CCC(CC)c1cc(C)nc2c(-c3sc(COC)nc3Cl)c(C)nn12,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20130116235A1,Cn1cc(-c2cncc(-n3ccn4c5c(cc4c3=O)CCCC5)c2C=O)cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c1=O>>Cn1cc(-c2cncc(-n3ccn4c5c(cc4c3=O)CCCC5)c2CO)cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c1=O,,CO,,[BH4-].[Na+],,test
US20160038504A1,O=C([O-])C(F)(F)Cl.Oc1ncc(Br)cc1N1CCOCC1>>FC(F)Oc1ncc(Br)cc1N1CCOCC1,,CN(C)C=O,,[Na+].[OH-],,test
US20130267534A1,CCOC(=O)C1CCC2(CC1)Oc1ccccc1O2.O=S(=O)(c1ccccc1)N(F)S(=O)(=O)c1ccccc1>>CCOC(=O)C1(F)CCC2(CC1)Oc1ccccc1O2,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20100024683A1,C=C(C)C(=O)Cl.Nc1cccc(O)c1>>C=C(C)C(=O)Nc1cccc(O)c1,,CC(=O)N(C)C,,,,test
US20110021537A1,CCO.CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)O)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)NC3CCC3)n(-c3ccccc3)n2)CC1>>CCOC(=O)CC[C@H](NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1)C(=O)N1CCN(C(=O)OCC)CC1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20090233967A1,CC(=O)N[C@@H](C)c1cc(Cl)ccc1C1CCN(C(=O)[C@@H]2CN(C(C)(C)C)C[C@H]2c2ccc(F)cc2F)CC1.CC(=O)OC(C)C.CC(C)O.Cl>>CC(=O)N[C@@H](C)c1cc(Cl)ccc1C1CCN(C(=O)[C@@H]2CN(C(C)(C)C)C[C@H]2c2ccc(F)cc2F)CC1.CC(=O)OC(C)C.CC(C)O.Cl,,CC(C)O,,,,test
US20140275096A1,C[C@H]1CNC(=S)CN1C(=O)OC(C)(C)C.NNC(=O)c1cnccn1>>C[C@H]1Cn2c(nnc2-c2cnccn2)CN1C(=O)OC(C)(C)C,,CCCCO,,,,test
US07442833B2,CC/C(=C(/c1ccc(O)cc1)c1ccc(/C=C/C(=O)O[Si](C)(C)C(C)(C)C)cc1)c1ccccc1.CCC(=O)Cl>>CCC(=O)Oc1ccc(/C(=C(/CC)c2ccccc2)c2ccc(/C=C/C(=O)O)cc2)cc1,,C1CCOC1,ClCCl,CCN(CC)CC,O,test
US04366154,NCCCC1(c2ccc(F)cc2)OCCO1.O=C1C=CCCC=C1>>O=C1CC2CCC(C1)N2CCCC1(c2ccc(F)cc2)OCCO1,,CO,,,,test
US20090318412A1,CC(C)(C)OC(=O)N1CCNC(CO)C1.O=C(Cl)c1cc(Cl)ccc1F>>CC(C)(C)OC(=O)N1CCN(C(=O)c2cc(Cl)ccc2F)C(CO)C1,,C1CCOC1,,CCN(CC)CC,O,test
US20070149519A1,COc1cc2ncn(-c3cc(OCc4ccc(CO)cc4)c(C(N)=O)s3)c2cc1OC>>COc1cc2ncn(-c3cc(OCc4ccc(CO)cc4)c(C#N)s3)c2cc1OC,,ClCCl,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,c1ccncc1,test
US05135945,BrBr.Cc1c(C)c2c(c(C)c1O)CCC(C)(CCO)O2>>Cc1c(C)c2c(c(C)c1O)CCC(C)(CCBr)O2,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100266504A1,CC1(C)CN(Cc2ccccc2)Cc2ccc(Cl)nc21.CCC(C)[Mg]Br>>CCC(C)c1ccc2c(n1)C(C)(C)CNC2.Cl,,C1CCOC1,,,,test
US20140356415A1,CCCCCCCCCCCC(=O)O.O=C1CCC(=O)N1O>>CCCCCCCCCCCC(=O)N1C(=O)CCC1=O,,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,Cl,test
US20120149632A1,CN(C)CCN(C)C(=O)COCc1ccccc1.Cl>>CN(C)CCN(C)C(=O)CO.Cl,[Pd],CO,,[H][H],,test
US05891889,Cc1cccc(Cl)[n+]1[O-].OCc1ccccc1>>Cc1cccc(OCc2ccccc2)[n+]1[O-],,CS(C)=O,,[H-].[Na+],,test
US04049669,CN=C(NC#N)SC.Cc1ncsc1CSCCN>>CNC(=NCCSCc1scnc1C)NC#N,,CC#N,,,,test
US20120253043A1,Brc1cc(C=Cc2scc3c2OCCO3)ccn1.COC(=O)c1ccnc([Sn](C)(C)C)c1>>COC(=O)c1ccnc(-c2cc(C=Cc3scc4c3OCCO4)ccn2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US04931463,CCCCCCCCCCCC(CC(O)[C@@H](CCCCCC)C(=O)O)OC1CCCCO1>>CCCCCCCCCCCC1CC(O)[C@@H](CCCCCC)C(=O)O1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05114952,CNCC(O)c1ccc(NS(C)(=O)=O)cc1.O=c1cc(-c2ccccc2)cnn1CCBr>>CN(CCn1ncc(-c2ccccc2)cc1=O)CC(O)c1ccc(NS(C)(=O)=O)cc1,,CCO,,CCN(CC)CC,,test
US20080125427A1,COC(=O)CC(C)=O.COc1ccc(C(=N)N)cc1.O=Cc1ccc(Cl)cc1F>>COC(=O)C1=C(C)NC(c2ccc(OC)cc2)=NC1c1ccc(Cl)cc1F,,CCOC(C)=O,CS(C)=O,CC(=O)[O-].[K+],,test
US20070244132A1,Clc1ncnc2cc[nH]c12.Nc1ccc(OCc2ccccc2)c(CO)c1>>OCc1cc(Nc2ncnc3cc[nH]c23)ccc1OCc1ccccc1,,CN(C)C=O,,,,test
US03932479,O=C(O)CCCCCCC1=CCCC1=O.O=C1CCC(=O)N1Br>>O=C(O)CCCCCCC1=CC(Br)CC1=O,,ClC(Cl)(Cl)Cl,,,,test
US20120214803A1,Brc1nccs1.SCc1ccccc1>>c1ccc(CSc2nccs2)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100113774A1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.COc1cc(OC)c(NC(=O)Cn2c(=O)n(CC(=O)O)c(=O)c3ccccc32)cc1Cl>>COc1cc(OC)c(NC(=O)Cn2c(=O)n(CC(=O)N3CC[C@H](NC(=O)OC(C)(C)C)C3)c(=O)c3ccccc32)cc1Cl,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05294626,CC(C)(C)OC(=O)NC1CCc2cc(Br)ccc2C1.O=Cc1cccnc1>>CC(C)(C)OC(=O)NC1CCC2=C(C=CC(Br)(C(O)c3cccnc3)C2)C1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20160264518A1,CCOC(=O)/C=C/c1ccccc1N1CCN(C(=O)OC(C)(C)C)CC1=O.Cl>>CCOC(=O)/C=C/c1ccccc1N1CCNCC1=O.Cl,,CCOC(C)=O,,C1COCCO1,,test
US20150104384A1,N#Cc1ccc(S(=O)(=O)N2CCNCC2)cc1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>N#Cc1ccc(S(=O)(=O)N2CCN(CC(F)(F)F)CC2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20140171422A1,COS(=O)(=O)c1ccc(C)cc1.O=c1[nH]ccc2occ(Br)c12>>Cn1ccc2occ(Br)c2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20100056550A1,CC(C)(C)OC(=O)N1Cc2nn3nccnc3c2C1>>c1cnn2nc3c(c2n1)CNC3,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020086890A1,CC#CCBr.O=S(=O)([O-])c1ccc(O)cc1.[Na+]>>CC#CCOc1ccc(S(=O)(=O)[O-])cc1.[Na+],,CC(C)O,,[Na+].[OH-],,test
US20150141427A1,O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(C2=CCOCC2)c(-c2cncnc2)c1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(C2CCOCC2)c(-c2cncnc2)c1,O=[Pt]=O,CC(=O)O,,,,test
US20030018067A1,CCCCC(=O)c1c(-c2ccc3cc(OCC(=O)OCC)ccc3c2)oc2ccc(Cl)cc12>>CCCCC(=O)c1c(-c2ccc3cc(OCC(=O)O)ccc3c2)oc2ccc(Cl)cc12,,C1CCOC1,O,[K+].[OH-],,test
US05780437,CCCCC(=O)Cl.Cc1cc(C)cc(-c2[nH]c3ccc(N)cc3c2CCN(Cc2ccccc2)C(=O)OC(C)(C)C)c1>>CCCCC(=O)Nc1ccc2[nH]c(-c3cc(C)cc(C)c3)c(CCN(Cc3ccccc3)C(=O)OC(C)(C)C)c2c1,,CCN(CC)CC,,,,test
US20070111995A1,CC(C)(C)OC(=O)NC1CCC(F)(F)CC1.Cl>>Cl.NC1CCC(F)(F)CC1,,C1COCCO1,,,,test
US05344991,CSc1ccc(C2=C(Br)CCC2)cc1.OB(O)c1ccc(F)cc1>>CSc1ccc(C2=C(c3ccc(F)cc3)CCC2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20080286265A1,COc1cc(C=O)ccc1O.N#Cc1ccc(F)c(C(F)(F)F)c1>>COc1cc(C=O)ccc1Oc1ccc(C#N)cc1C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080039426A1,C=CP(C)(=O)C=C.NCc1ccccc1>>CP1(=O)CCN(Cc2ccccc2)CC1,,C1CCOC1,O,,,test
US05260298,Clc1nc2ccccc2c2nncn12.[C-]#[N+]Cc1noc(C2CC2)n1>>c1ccc2c(c1)c1nncn1c1c(-c3noc(C4CC4)n3)ncn21,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US04451471,C=CCBr.COc1ccc(C2=NC(=S)SC2c2ccc(OC)cc2)cc1>>C=CCSc1nc(-c2ccc(OC)cc2)c(-c2ccc(OC)cc2)s1,,[Na+],[OH-],,,test
US20110312908A1,CCOC(=O)CCn1ccc2c(Nc3ccc(OC(F)(F)F)cc3)ncnc21>>O=C(O)CCn1ccc2c(Nc3ccc(OC(F)(F)F)cc3)ncnc21,,C1CCOC1,O,,,test
US20150105373A1,CC(C)(C)OC(=O)NC(CC(N)=O)c1ccc(OC(F)(F)F)c(F)c1>>CC(C)(C)OC(=O)NC(CC#N)c1ccc(OC(F)(F)F)c(F)c1,,C1CCOC1,Cc1ccccc1,O=S(Cl)Cl,,test
US20060122248A1,Cc1c(NC=O)cc(C(N)=O)c2nc[nH]c12>>Cc1c(N)cc(C(N)=O)c2nc[nH]c12,,CO,,Cl,,test
US20050261358A1,CN(C)C1(c2ccccc2)CCC(CCN)CC1.NCCc1c[nH]c2ccccc12.S=C(Cl)Cl>>CN(C)C1(c2ccccc2)CCC(CCNC(=S)NCCc2c[nH]c3ccccc23)CC1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US06011044,CN.COc1ccccc1N1CCc2c(Cl)nc3c(OCC(F)(F)F)cccc3c21>>CNc1nc2c(OCC(F)(F)F)cccc2c2c1CCN2c1ccccc1OC,,O,,,,test
US20090270374A1,C1COCCO1.Cc1ccc2ccc(=O)oc2n1>>O=Cc1ccc2ccc(=O)oc2n1,,ClCCl,,,,test
US06545000B1,CSc1nc(Cl)cc(Cl)n1.NNC(=O)c1ccco1>>CSc1nc(Cl)cc(NNC(=O)c2ccco2)n1,,CN(C)C=O,,C1CCC2=NCCCN2CC1,Cl,test
US20100168082A1,COC(OC)N(C)C.Cc1c([N+](=O)[O-])ccc(OCc2ccccc2)c1F>>Oc1ccc2[nH]ccc2c1F,[Pd],,,,,test
US20120202785A1,COc1cccc(Nc2cc(F)ccc2[N+](=O)[O-])c1>>COc1cccc(Nc2cc(F)ccc2N)c1,,CCOC(C)=O,,,,test
US20090093483A1,CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2ccccc2C(C)(C#N)C1=O>>CC1(C#N)C(=O)C(C(=O)NCC(=O)O)=C(O)c2ccccc21,,O=C(O)C(F)(F)F,,,,test
US20090105318A1,NC1CCC1.O=CCOCc1ccccc1>>c1ccc(COCCNC2CCC2)cc1,,CO,,[BH4-].[Na+],,test
US04197296,C/C=C1/CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C.NO>>C/C=C1/CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=NO)C[C@]12C,,O,,Cl,[Na+].[OH-],test
US20130116249A1,CI.COc1c(C)c(C(=O)c2ccc(N)c(C(=O)O)c2)n2ccccc12>>COC(=O)c1cc(C(=O)c2c(C)c(OC)c3ccccn23)ccc1N,,CN(C)C=O,,O,[Na],test
US20100137587A1,BrCCc1ccccc1.CC(C)CN(C(=O)c1nc2ccccc2[nH]1)[C@H]1C[C@@H](C(=O)N2CCOCC2)CN(C(=O)OC(C)(C)C)C1>>CC(C)CN(C(=O)c1nc2ccccc2n1CCc1ccccc1)[C@H]1C[C@@H](C(=O)N2CCOCC2)CN(C(=O)OC(C)(C)C)C1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110306618A1,CCOC(=O)C1CCC(N)CC1.Clc1nccc(-c2cnc3c(OCc4ccccc4)cccn23)n1>>CCOC(=O)C1CCC(Nc2nccc(-c3cnc4c(OCc5ccccc5)cccn34)n2)CC1,,CN1CCCC1=O,O,,,test
US20030229066A1,CC(=O)Cl.COC(=O)c1sc2c(C(F)(F)F)cccc2c1C1CCNCC1>>COC(=O)c1sc2c(C(F)(F)F)cccc2c1C1CCN(C(C)=O)CC1,,CCOC(C)=O,,C1CCOC1,CCN(CC)CC,test
US20050054638A1,N#Cc1cc(-c2ccccn2)ccn1>>NCc1cc(-c2ccccn2)ccn1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04642347,ClCc1ccc2ccccc2n1.Oc1cccc(O)c1>>Oc1cccc(OCc2ccc3ccccc3n2)c1,,CCO,,Cl,[K+].[OH-],test
US06756378B2,COC(=O)c1ccc(OC[C@@H]2CCCN2)cc1C(=O)OC.COc1cc(CC(=O)O)ccc1NC(=O)Nc1ccccc1C>>COC(=O)c1ccc(OC[C@@H]2CCCN2C(=O)C(NC(=O)Nc2ccccc2C)c2cccc(OC)c2)cc1C(=O)OC,,CN(C)C=O,,CCN(CC)CC,CCOC(C)=O,test
US20140155597A1,BrBr.CC(=O)C(=O)c1ccc(C(F)(F)F)cc1>>O=C(CBr)C(=O)c1ccc(C(F)(F)F)cc1,,ClC(Cl)Cl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20140057909A1,COC(=O)COc1cccc(C(=O)NN(C(=O)/C=C/c2cn(C(=O)OC(C)(C)C)c3ccccc23)C(C)C)c1>>CC(C)N(NC(=O)c1cccc(OCC(=O)O)c1)C(=O)/C=C/c1cn(C(=O)OC(C)(C)C)c2ccccc12,,C1CCOC1,O,[Li+].[OH-],,test
US20060166993A1,COc1cc(Oc2nc(-c3cccc([N+](=O)[O-])c3)nn3c(C)nc(C)c23)cc(OC)c1OC>>COc1cc(Oc2nc(-c3cccc(N)c3)nn3c(C)nc(C)c23)cc(OC)c1OC,[Pd],,,,,test
US20140200227A1,C[C@H]1CN(c2c(N)cnc3c2CCO3)C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C.O=C(O)c1ccc(F)c(-c2c(F)cccc2F)n1>>C[C@H]1CN(c2c(NC(=O)c3ccc(F)c(-c4c(F)cccc4F)n3)cnc3c2CCO3)C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04657842,O=C1c2ccccc2C(=O)c2cc(CCl)ccc21.[N-]=[N+]=[N-]>>[N-]=[N+]=NCc1ccc2c(c1)C(=O)c1ccccc1C2=O,,CN(C)C=O,,O,,test
US20160015690A1,Cc1nn(C)c2c1CN(C(=O)OC(C)(C)C)CC2.O=C(O)C(F)(F)F>>Cc1nn(C)c2c1CNCC2.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20140179689A1,BrCCc1ccccc1.Oc1cccc2[nH]ccc12>>c1ccc(CCOc2cccc3[nH]ccc23)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05811428,O=C(Cl)C(=O)Cl.O=C(O)c1cnc(Cl)nc1C(F)(F)F>>O=C(Cl)c1cnc(Cl)nc1C(F)(F)F,,ClCCl,,,,test
US20030181726A1,COc1ccc(C(O)(CCNC[C@H](O)COc2ccccc2)c2ccc(OC)cc2)cc1.O=C(O)C(F)(F)F>>COc1ccc(C(CCNC[C@H](O)COc2ccccc2)c2ccc(OC)cc2)cc1.O=C(O)C(F)(F)F,,ClCCl,,CC[SiH](CC)CC,,test
US20090176786A1,CI.CN(C(=O)NC(=O)c1c(Cl)cccc1Cl)c1ccc(SC(F)(F)F)cc1F>>CN(C(=O)c1c(Cl)cccc1Cl)C(=O)N(C)c1ccc(SC(F)(F)F)cc1F,,CN1CCCC1=O,O,[H-].[Na+],[Cl-].[NH4+],test
US06049006,CC(=O)NCC(=O)c1ccccc1.NNC(N)=S>>CC(=O)NCC(=NNC(N)=S)c1ccccc1,,CO,,Cl,O,test
US20060166985A1,CC(C)(C)OC(=O)N[C@@H](Cc1cccs1)C(=O)N1CCOCC1>>N[C@@H](Cc1cccs1)C(=O)N1CCOCC1,,C1COCCO1,ClCCl,Cl,,test
US20040122016A1,CCOC(=O)c1c(-c2ccncc2)csc1N>>Nc1cc(-c2ccncc2)cs1,,O,,CCO,[K+].[OH-],test
US20060235031A1,CCOC(=O)[C@H]1CC[C@@H](n2cc(I)c3c(Cl)ncnc32)CC1.N>>CCOC(=O)[C@@H]1CC[C@H](n2cc(I)c3c(N)ncnc32)CC1,,CC(C)O,,,,test
US06359134B1,Cl.O=CN1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1>>Cl.O=S(=O)(c1ccc2ccccc2c1)N1CCNCC1,,CCO,,,,test
US20150191483A1,Fc1cccc(F)c1CBr.O=S(=O)(Cc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)c1ccc(F)c(Br)c1>>O=S(=O)(Cc1ccc(C(OCc2c(F)cccc2F)(C(F)(F)F)C(F)(F)F)cc1)c1ccc(F)c(Br)c1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20060110743A1,CCOC(=O)c1ccc(N)cc1.O=C1CCC(=O)N1Br>>CCOC(=O)c1ccc(N)c(Br)c1,,CC#N,,,,test
US20080114056A1,CC(=O)c1ccc(O)cc1O.COc1ccc(CCl)cc1>>COc1ccc(COc2ccc(C(C)=O)c(O)c2)cc1,,CC(C)=O,O,[I-].[K+],,test
US20090131468A1,NS(=O)(=O)c1ccccc1S(N)(=O)=O.O=C(O)c1ccc(Br)cc1>>NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(Br)cc1,CN(C)c1ccncc1,CN(C)C=O,O,ClCCCl,,test
US20130317001A1,CS(N)(=O)=O.O=C(O)c1cc(C2CC2)c(OC2CN(C(c3ccccc3)c3ccccc3)C2)cc1F>>CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OC2CN(C(c3ccccc3)c3ccccc3)C2)cc1F,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20100174065A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c3OCCNC4)no2)cc1C#N.CCOC(=O)CBr>>CCOC(=O)CN1CCOc2c(cccc2-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)C1,,CC#N,,CCN(C(C)C)C(C)C,,test
US05744627,CC(C)(C)OC(=O)NCCCCCC(=O)ON1C(=O)CCC1=O.COC(=O)c1ccc(CN)cc1O>>COC(=O)c1cccc(C(=O)CCCCCNC(=O)OC(C)(C)C)c1OCN,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20040102479A1,CCOC(C)=O.O=C(Cl)CCC(F)(F)C(F)(F)F>>CCOC(=O)CC(=O)CCC(F)(F)C(F)(F)F,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20030207858A1,CC(C)(C)OC(=O)N1CC(O)C1.Oc1cccnc1>>CC(C)(C)OC(=O)N1CC(Oc2cccnc2)C1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090275523A1,COC(=O)[C@@H](N)CC(C)(F)F.O=C(Cl)Cl>>COC(=O)[C@H](CC(C)(F)F)N=C=O,,Cc1ccccc1,ClCCl,Cl,c1ccncc1,test
US04596870,ClCOc1ccc(Cl)cc1.O=c1ncc(C(F)(F)F)c[nH]1>>O=c1ncc(C(F)(F)F)cn1COc1ccc(Cl)cc1,,ClCCl,,CCN(CC)CC,,test
US20090137609A1,C#CC1(O)CCCCC1.CCC(CC)(c1ccc(O)c(C)c1)c1ccc(OS(=O)(=O)C(F)(F)F)c(C)c1>>CCC(CC)(c1ccc(O)c(C)c1)c1ccc(C#CC2(O)CCCCC2)c(C)c1,,CC#N,,CCN(CC)CC,,test
US20130190290A1,CC(C)(O)c1cc(C(=O)O)cc(S(F)(F)(F)(F)F)c1.Cc1ccc(N)cc1-n1ccn2nc(-c3cccnc3)c(F)c12>>Cc1ccc(NC(=O)c2cc(C(C)(C)O)cc(S(F)(F)(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)c(F)c12,,CC#N,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110034450A1,CC(C)(C)OC(=O)C(c1ccc(CN2Cc3cc(F)c(F)cc3C2=O)cc1)C1CCCC1>>O=C(O)C(c1ccc(CN2Cc3cc(F)c(F)cc3C2=O)cc1)C1CCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04420424,COC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1)C(C)C)C(C)C.Cl>>COC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(=O)OC(C)(C)C)C(C)C)C(C)C.Cl,,CO,,,,test
US04904690,O=c1cc(C2(Br)CCCCC2)oc2c(CBr)cccc12.[C-]#N>>N#CCc1cccc2c(=O)cc(C3(Br)CCCCC3)oc12,,CN(C)C=O,,O,,test
US05281747,CC(C)COP(C)(=O)C[C@@H](O)CN=[N+]=[N-]>>CC(C)COP(C)(=O)C[C@@H](O)CN,[Pd],CCO,,[H][H],,test
US05212180,C=C[Mg]Br.O=Cc1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1>>C=CC(O)c1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1,,Cc1ccccc1,,C1CCOC1,,test
US20160237045A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2ccc(-c3ccccc3CO)cc2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)CC1.Cl>>Cl.NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2ccc(-c3ccccc3CO)cc2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)CC1,,C1CCOC1,C1COCCO1,,,test
US20150087646A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N#Cc1cnc(C2CC2)c(-c2nn(-c3ccc(C(F)(F)F)cc3)c(=O)[nH]2)c1>>CC(C)(C)OC(=O)NCc1cnc(C2CC2)c(-c2nn(-c3ccc(C(F)(F)F)cc3)c(=O)[nH]2)c1,[Pd],CCO,,,,test
US05798375,CC(=O)Oc1c(C)cc(N(C)C(=O)OC(C)(C)C)c(C)c1C.Cl>>CNc1cc(C)c(OC(C)=O)c(C)c1C.Cl,,C1COCCO1,,,,test
US20060004013A1,CCOP(=O)(CC(=O)NC1CCc2ccccc21)OCC.COc1cc(C=O)ccc1-n1cnc(C)c1>>COc1cc(/C=C/C(=O)NC2CCc3ccccc32)ccc1-n1cnc(C)c1,,C1CCOC1,,O,[Li+].[OH-],test
US04640913,C1COCO1.CCCCCCCCCCCCCCc1ccc(O)cc1.CN(C)C=O>>CCCCCCCCCCCCCCc1ccc(OCC(O)CO)cc1,,CCCCCC,CCOCC,[H-].[Na+],,test
US20150065482A1,CCOC(=O)c1cnc(SC)nc1Cl.NN>>CSc1ncc2c(=O)[nH][nH]c2n1,,CCO,O,CC(=O)O,[Na+].[OH-],test
US20160038504A1,CC(F)(F)c1cc(C(=O)O)ccn1.Cc1ncc(N)cc1-c1cc(N2CCOCC2)c(OC2CCOCC2)nn1>>Cc1ncc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOCC2)c(OC2CCOCC2)nn1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05412137,OCCCCCCCCBr.Oc1ccc(OC(F)(F)F)cc1>>OCCCCCCCCOc1ccc(OC(F)(F)F)cc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20130338196A1,CC(C)(C)[Si](C)(C)Cl.O=C(c1ncco1)C1Cc2ccc(OCc3ccccc3)cc2C1>>CC(C)(C)[Si](C)(C)OC(c1ncco1)C1Cc2ccc(OCc3ccccc3)cc2C1,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US20080280872A1,COC[C@H](C)Oc1cc(Oc2ccc(C(=O)N3CCC3)cc2F)cc(C(=O)OC)c1>>COC[C@H](C)Oc1cc(Oc2ccc(C(=O)N3CCC3)cc2F)cc(C(=O)O)c1,,C1CCOC1,O,[Na+].[OH-],,test
US05472978,NC(Cc1csc2ccccc12)C(=O)O>>NC(CO)Cc1csc2ccccc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060040965A1,CO[C@H]1CC[C@H]1CNc1ncnc2[nH]c(-c3ccc(OCCN(C)C)cc3)c(-c3ccccc3)c12>>CN(C)CCOc1ccc(-c2[nH]c3ncnc(NC[C@H]4CC[C@H]4O)c3c2-c2ccccc2)cc1,,ClCCl,,BrB(Br)Br,,test
US20090005376A1,CCCCC(=O)Cl.Nc1cnc2cccnc2c1O>>CCCCC(=O)Nc1cnc2cccnc2c1O,,ClCCl,,CCN(CC)CC,,test
US20030109459A1,COC(=O)C1(CCBr)CCCC1.C[S-]>>COC(=O)C1(CCSC)CCCC1,,CN(C)C=O,,O,,test
US20090325967A1,CCC(=O)Cl.CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(N4CC[C@@H](Nc5nc(Cl)nc6c5ncn6[C@@H]5C[C@H](N)[C@@H](O)[C@H]5O)C4)nc32)[C@H](O)[C@@H]1O>>CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(N4CC[C@@H](Nc5nc(Cl)nc6c5ncn6[C@@H]5C[C@H](NC(=O)CC)[C@@H](O)[C@H]5O)C4)nc32)[C@H](O)[C@@H]1O,,C1CCOC1,,CO,,test
US20160264553A1,COC(=O)c1ccnc(-c2cccc(C)n2)c1-c1ccc2ncc(C#N)n2c1>>Cc1cccc(-c2nccc(CO)c2-c2ccc3ncc(C#N)n3c2)n1,,CO,O,[BH4-].[Na+],,test
US20160122302A1,Cc1cc(C#Cc2cccc(C(Cc3cc(C)cc(-n4c(C)ccc4C)n3)C[N+](=O)[O-])n2)nc(-n2c(C)ccc2C)c1>>Cc1cc(CCc2cccc(C(CN)Cc3cc(C)cc(-n4c(C)ccc4C)n3)n2)nc(-n2c(C)ccc2C)c1,[Ni],CCO,CO,,,test
US20050288273A1,CC(=N)N.CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCC(Br)C3=O)C(=O)O1>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCc2[nH]c(C)nc2-3)C(=O)O1,,CN(C)C=O,ClC(Cl)Cl,,,test
US20060004017A1,COc1cc2c(=O)[nH]cnc2cc1OCCN1CCCCC1.O=S(Cl)Cl>>COc1cc2c(Cl)ncnc2cc1OCCN1CCCCC1.Cl,CN(C)C=O,,,,,test
US20020147229A1,COC(=O)[C@H](Cc1c[nH]cn1)NC(=O)OC(C)(C)C.FC(F)(F)CCCBr>>COC(=O)[C@H](Cc1cn(CCCC(F)(F)F)cn1)NC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160068559A1,CC(C)N(CCCNC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21>>CC(C)N(CCCNC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O,,O=C(O)C(F)(F)F,,O,O=C([O-])[O-].[K+].[K+],test
US20060257987A1,CCCC(Br)CCO.CCOC(=O)COc1ccc(S)cc1C>>CCCC(CCO)Sc1ccc(OCC(=O)OCC)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080194556A1,CCOc1cc(OC)c2c(Nc3cnn(CC(=O)Nc4cccc(F)c4F)c3)ncnc2c1>>CCOc1cc(O)c2c(Nc3cnn(CC(=O)Nc4cccc(F)c4F)c3)ncnc2c1,,c1ccncc1,,Cl,,test
US20150299194A1,CC(C)(O)CN.CCOCC(OCC)(OCC)OCC.N#CC(N)C#N>>CCOCc1nc(C#N)c(N)n1CC(C)(C)O,,C1CCOC1,,CCN(CC)CC,Cc1ccc(S(=O)(=O)O)cc1,test
US03971819,CN(C)CCCNc1c([N+](=O)[O-])cc(C(=O)O)cc1S(N)(=O)=O>>CN(C)CCCNc1c(N)cc(C(=O)O)cc1S(N)(=O)=O,[Pd],[Na+],[OH-],[H][H],,test
US20030069424A1,CC(=O)Oc1cc(Br)c2c(c1)CCCC2>>Oc1cc(Br)c2c(c1)CCCC2,,CO,,C[O-].[Na+],,test
US20060148858A1,CCOc1cc(O)ccc1CCC(=O)OC.CCOc1nn(-c2ccccn2)cc1CCCO>>CCOc1cc(OCCCc2cn(-c3ccccn3)nc2OCC)ccc1CCC(=O)O,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20160264548A1,CC(C)(C)OC(=O)NCCN1CCNCC1.NC(=O)c1ccc(C2CCN(C(=O)/C=C/COn3nnc4cccnc43)CC2)nc1Oc1ccc(Oc2ccccc2)cc1>>CC(C)(C)OC(=O)NCCN1CCN(C/C=C/C(=O)N2CCC(c3ccc(C(N)=O)c(Oc4ccc(Oc5ccccc5)cc4)n3)CC2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20160237090A1,C=C(C(=O)OC)c1cnn2c1CN(C(=O)OC(C)(C)C)[C@@H](C)C2.C[N+](=O)[O-]>>COC(=O)C(CC[N+](=O)[O-])c1cnn2c1CN(C(=O)OC(C)(C)C)[C@@H](C)C2,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20120259123A1,CCCCC1(c2ccc(CC(NS(=O)(=O)c3cn(C)cn3)c3cccc(N(CC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n3)cc2)CC1>>CCCCC1(c2ccc(CC(NS(=O)(=O)c3cn(C)cn3)c3cccc(NCC(=O)O)n3)cc2)CC1,,O,,C1CCOC1,Cl,test
US20070142432A1,COC(=O)CCN1CCC(Oc2ccc(Oc3ccccc3)cc2)CC1>>O=C(O)CCN1CCC(Oc2ccc(Oc3ccccc3)cc2)CC1,,CO,O,[Na+].[OH-],,test
US20160200674A1,O=[N+]([O-])c1cc(Br)ccc1N(CCC(F)(F)F)Cc1ccccc1>>Nc1cc(Br)ccc1N(CCC(F)(F)F)Cc1ccccc1,[Zn],CCO,ClCCl,O,[Cl-].[NH4+],test
US20150218102A1,COC(=O)c1ccc2cc(O)ccc2n1.Fc1ccc(C(F)(F)F)nc1>>COC(=O)c1ccc2cc(Oc3ccc(C(F)(F)F)nc3)ccc2n1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100298336A1,BrP(Br)Br.CCc1ncsc1CO>>CCc1ncsc1CBr,,ClCCl,,,,test
US20110263603A1,Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1/C=N/OCC(=O)O.NCC(F)(F)F>>Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1/C=N/OCC(=O)NCC(F)(F)F,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20030078260A1,CC(C)(C)OC(=O)N(C[C@H](O[Si](C)(C)C(C)(C)C)c1cccnc1)C[C@H]1CCc2cc(-c3ccnc(C(=O)O)c3)ccc2O1>>O=C(O)c1cc(-c2ccc3c(c2)CC[C@H](CNC[C@H](O)c2cccnc2)O3)ccn1,,C1COCCO1,,Cl,,test
US20160168139A1,O=c1cc(N2CCOCC2)cc(-c2cccc3c2Oc2ccc(CCl)cc2C3)[nH]1.c1cn[nH]c1>>O=c1cc(N2CCOCC2)cc(-c2cccc3c2Oc2ccc(Cn4cccn4)cc2C3)[nH]1,,CC(=O)N(C)C,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20060009453A1,Cc1ccc(S(=O)(=O)OCCCl)cc1.O=[N+]([O-])c1cc(O)cc(C(F)(F)F)c1>>O=[N+]([O-])c1cc(OCCCl)cc(C(F)(F)F)c1,,O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110092547A1,CC(C)(C)OC(=O)C1CCC(Oc2ccc(NC(=O)C(=O)NN)cn2)CC1.Fc1cc(F)c(N=C=S)cc1F>>CC(C)(C)OC(=O)C1CCC(Oc2ccc(NC(=O)c3nnc(Nc4cc(F)c(F)cc4F)o3)cn2)CC1,,CN(C)C=O,,CCN=C=NCCCN(C)C,Cl,test
US20060223863A1,CCn1cc(C(C)=NO)c2ccc(OC)cc21.CN(C)C=O>>CCn1cc(-c2ccon2)c2ccc(OC)cc21,,C1CCOC1,,O,[Li]CCCC,test
US20090181928A1,O=C(CCc1ccccc1)c1ccccc1.O=[N+]([O-])c1ccc(CBr)cc1OCc1ccccc1>>O=C(c1ccccc1)C(Cc1ccccc1)Cc1ccc([N+](=O)[O-])c(OCc2ccccc2)c1,,C1CCOC1,CCOC(C)=O,[Cl-].[NH4+],C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20040122050A1,O=C(CC1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1)c1cccc(C2OCCO2)c1>>O=Cc1cccc(C(=O)CC2CCC(c3cc(F)ccc3F)(S(=O)(=O)c3ccc(Cl)cc3)CC2)c1,,CC(C)=O,O,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20040142949A1,Cc1ccc(CN2C(=O)NCCC2C(=O)Nc2cc(Cl)ccc2C(=O)NCc2ccccc2)cc1>>Cc1ccc(CN2C(=O)NCCC2c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)cc1,,OCCO,,[Na+].[OH-],,test
US20150368246A1,CCOC(OCC)OCC.Nc1ccc(Cl)nc1-c1cc2c(F)cccc2[nH]1>>Fc1cccc2c1cc1c3nc(Cl)ccc3ncn21,,C1COCCO1,,Cl,,test
US20080045537A1,CC(=O)OC(C)=O.CN(Cc1nc2c(N3CCNCC3)cccc2[nH]1)C1CCCc2cccnc21>>CC(=O)N1CCN(c2cccc3[nH]c(CN(C)C4CCCc5cccnc54)nc23)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20020161036A1,CC=CCOc1ccc2c(C)cc(=O)oc2c1C(C)=O.COc1cccc(C=O)c1>>C=C(C)COc1ccc2c(C)cc(=O)oc2c1C(=O)C=Cc1cccc(OC)c1,,O,,CCO,[K+].[OH-],test
US20090221583A1,O=C(NCC(=O)N1CCNCC1)c1ccc(Oc2ccccc2)cc1.O=S(=O)(Cl)c1ccccc1>>O=C(NCC(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1)c1ccc(Oc2ccccc2)cc1,,ClCCl,,Cl,O,test
US06310095B1,BrC(Br)(Br)Br.COC(=O)[C@H](CCSC)NC(=O)c1ccc(CO)cc1-c1ccccc1C>>COC(=O)[C@H](CCSC)NC(=O)c1cccc(CBr)c1-c1ccccc1C,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US05948775,C1CCNCC1.O=c1c2ccc(O)cc2nc(-c2ccc(O)cc2)n1-c1ccc(OCCCl)cc1>>O=c1c2ccc(O)cc2nc(-c2ccc(O)cc2)n1-c1ccc(OCCN2CCCCC2)cc1,,C1CCNCC1,,CCOC(C)=O,,test
US05709820,COC(=O)[C@@H]1CC[C@@H]([C@@H]2CC[C@@H]([C@@H]3CC[C@@H](CCC4OCCCO4)CC3)CC2)CC1>>COC(=O)[C@@H]1CC[C@@H]([C@@H]2CC[C@@H]([C@@H]3CC[C@@H](CCC=O)CC3)CC2)CC1,,Cc1ccccc1,,O=CO,,test
US20100168418A1,CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCNCC1.O=CCn1c(=O)ccc2c([N+](=O)[O-])cccc21>>CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)ccc3c([N+](=O)[O-])cccc32)CC1,,CC(=O)O,ClC(Cl)Cl,O=C([O-])O.[Na+],,test
US05623081,CS(=O)(=O)Cl.C[C@H]1C[C@H](O)[C@@H](CN=[N+]=[N-])O1>>C[C@H]1C[C@H](OS(C)(=O)=O)[C@@H](CN=[N+]=[N-])O1,,CCCCCC,CCOC(C)=O,CCN(C(C)C)C(C)C,ClCCl,test
US20120129902A1,CC(C)(C)OC(=O)ON=C(C#N)c1ccccc1.N[C@]1(C(=O)O)[C@H]2[C@H]([C@@H]2C(=O)O)[C@H](O)[C@H]1CSc1ccc(F)c(F)c1>>CC(C)(C)OC(=O)N[C@]1(C(=O)O)[C@H]2[C@H]([C@@H]2C(=O)O)[C@H](O)[C@H]1CSc1ccc(F)c(F)c1,,C1COCCO1,O,CCN(CC)CC,,test
US05047540,CCCCCCCCCCCCCCCCCCNC(=O)SCC(CN)OC.O=S(=O)(Cl)CCCCl>>CCCCCCCCCCCCCCCCCCNC(=O)SCC(CNS(=O)(=O)CCCCl)OC,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US05262540,CCOC(=O)C=Cc1cccc(CCc2nc(-c3ccccc3)c(-c3ccccc3)o2)c1>>O=C(O)C=Cc1cccc(CCc2nc(-c3ccccc3)c(-c3ccccc3)o2)c1,,CO,,[Na+].[OH-],,test
US20060276450A1,C=CCn1c(C#N)c(-c2cccc(F)c2)c2cc(O)ccc2c1=O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>C=CCn1c(C#N)c(-c2cccc(F)c2)c2cc(OS(=O)(=O)C(F)(F)F)ccc2c1=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070173519A1,CC(C)(C)[Si](C)(C)Cl.OCCc1c(Cl)nc2ccnn2c1Cl>>CC(C)(C)[Si](C)(C)OCCc1c(Cl)nc2ccnn2c1Cl,,ClCCl,,CCN(CC)CC,[Cl-].[NH4+],test
US05705497,CCN(CC)CCOC(=O)Cl.COc1ccc(C(=O)N2CCCc3cc(C4=NNC(=O)SC4C)ccc32)cc1OC>>CCN(CC)CCOC(=O)N1N=C(c2ccc3c(c2)CCCN3C(=O)c2ccc(OC)c(OC)c2)C(C)SC1=O,,ClCCl,,CCN(CC)CC,,test
US20120015978A1,CCCCCCB(O)O.COC(=O)c1cccc2cc(OS(=O)(=O)C(F)(F)F)cnc12>>CCCCCCc1cnc2c(C(=O)OC)cccc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150210682A1,COCCCOc1cc(CC(NC=O)C(C)(C)C)ccc1OC>>COCCCOc1cc2c(cc1OC)C=NC(C(C)(C)C)C2,,CC#N,,O=P(Cl)(Cl)Cl,,test
US20030130278A1,Cn1c(=O)n(Cc2ccc(F)cc2)c(=O)c2cc(C#C[Si](C)(C)C)ccc21>>C#Cc1ccc2c(c1)c(=O)n(Cc1ccc(F)cc1)c(=O)n2C,,CO,,[Na+].[OH-],,test
US20080167303A1,NC1CC1.O=S1(=O)N(CCOCCBr)c2ccccc2N1c1c(F)cccc1F>>O=S1(=O)N(CCOCCNC2CC2)c2ccccc2N1c1c(F)cccc1F,,CO,,,,test
US20040029888A1,OCc1ncccc1OCCOC1CCCCO1>>O=Cc1ncccc1OCCOC1CCCCO1,,Cc1ccccc1,ClCCl,CS(C)=O,O=C(Cl)C(=O)Cl,test
US20060040968A1,N#CCc1cc(F)cc(F)c1>>NCCc1cc(F)cc(F)c1,,C1CCOC1,,,,test
US20100152068A1,CCCCCCCCCCCCCCCCCC(=O)[O-].NCCO.O=C([O-])[O-].O=C([O-])[O-].[K+].[K+].[Na+].[Na+].[Na+]>>CCCCCCCCCCCCCCCCCC(=O)[O-].NCCO.O=C([O-])[O-].O=C([O-])[O-].[K+].[K+].[Na+].[Na+].[Na+],,O,,,,test
US04766125,CC(O)C1CN(Cc2ccccc2)CCN1.Cc1cccc(C)c1NC(=O)CCl>>Cc1cccc(C)c1NC(=O)CN1CCN(Cc2ccccc2)CC1C(C)O,,CN(C)C=O,,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US20100105714A1,Cc1cccc(C2=C(c3ccc4ncnn4c3)OC3(CCC4(CC3)OCCO4)C2=O)n1>>Cc1cccc(C2=C(c3ccc4ncnn4c3)OC3(CCC(=O)CC3)C2=O)n1,,Cl,O,C1CCOC1,,test
US20060105997A1,CN(C)C(=O)Cl.Fc1ccc(F)c(C2=CC(c3ccccc3)NC2)c1>>CN(C)C(=O)N1CC(c2cc(F)ccc2F)=CC1c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20040121965A1,CCOC(=O)/C(=C/[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)CC.Cl>>CCOC(=O)/C(=C/[C@H](CC(C)C)N(C)C(=O)[C@@H](N)C(C)(C)C)CC.Cl,,C1COCCO1,,,,test
US20070225267A1,O=[N+]([O-])/C=C/c1cc(F)cc(Cl)c1>>O=[N+]([O-])CCc1cc(F)cc(Cl)c1,,C1COCCO1,,CCO,[BH4-].[Na+],test
US20070249670A1,COc1ccc(-c2cc(C(=O)OC(C)(C)C)c(NC(=O)Nc3c(C)cc(C)cc3C)s2)cc1>>COc1ccc(-c2cc(C(=O)O)c(NC(=O)Nc3c(C)cc(C)cc3C)s2)cc1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20100035919A1,C1=C(c2c[nH]c3ncccc23)CCNC1.Cc1nc(Cl)oc1-c1cccc(C(F)(F)F)c1>>Cc1nc(N2CC=C(c3c[nH]c4ncccc34)CC2)oc1-c1cccc(C(F)(F)F)c1,,CCCCO,CCOC(C)=O,Cl,,test
US20150239866A1,C#Cc1cc(C)cc(Nc2nccc(C(F)F)n2)c1.CC(C)(C)OC(=O)N1CCOC(CN=[N+]=[N-])C1>>Cc1cc(Nc2nccc(C(F)F)n2)cc(-c2cn(CC3CN(C(=O)OC(C)(C)C)CCO3)nn2)c1,,CC(C)(C)O,O,O=C(CO)O[CH][C@@H](O)CO,C[O-].[Na+],test
US20130018033A1,N.Nc1c(F)ccc(NS(=O)(=O)c2ccccc2)c1F.O=C(Cl)c1cccc2c(Cl)ncnc12>>Nc1ncnc2c(C(=O)Nc3c(F)ccc(NS(=O)(=O)c4ccccc4)c3F)cccc12,,C1COCCO1,ClC(Cl)Cl,,,test
US20070299064A1,CC(C)(C)C(=O)Cl.COc1ccc(NN)cc1>>COc1ccc(NNC(=O)C(C)(C)C)cc1,,O,,CCN(CC)CC,ClCCl,test
US20080275043A1,Cc1ccc(S(=O)(=O)OC2C(=O)N(C3CCCCC3)CC2(C)C)cc1.Sc1ccc(Cl)cc1Cl>>CC1(C)CN(C2CCCCC2)C(=O)C1Sc1ccc(Cl)cc1Cl,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US07553969B1,COC(=O)[C@@H](N)Cc1ccc(O)c(C(C)(C)C)c1.N>>CC(C)(C)c1cc(C[C@H](N)C(N)=O)ccc1O,,CO,,,,test
US20060217372A1,NC(=O)c1ccc(Oc2ccc(C=O)cc2F)cn1.NCCc1ccccc1F>>NC(=O)c1ccc(Oc2ccc(CNCCc3ccccc3F)cc2F)cn1,,CO,,[BH4-].[Na+],,test
US20090118263A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)Cc1cccc(CBr)c1.NCCCO>>CC(C)(C)OC(=O)N(CCCO)Cc1cccc(CC(=O)O)c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130131050A1,CS(=O)c1nc2c(c(=O)n1-c1ccc(OCC(F)(F)F)cc1)CCC(=O)N2.OCC(F)(F)F>>O=C1CCc2c(nc(OCC(F)(F)F)n(-c3ccc(OCC(F)(F)F)cc3)c2=O)N1,,C1CCOC1,,O,[H-].[Na+],test
US20160095858A1,C[C@H]1CC[C@@H](C)N1.Nc1cccc(S(=O)(=O)NC(=O)c2ccc(Cl)nc2Cl)n1>>C[C@H]1CC[C@@H](C)N1c1nc(Cl)ccc1C(=O)NS(=O)(=O)c1cccc(N)n1,,CS(C)=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20140080798A1,CN(C)C=O.Cc1cnc(Nc2cnn(C)c2)nc1C#Cc1ccccc1CC(=O)[O-]>>COC(=O)Cc1ccccc1CCc1nc(Nc2cnn(C)c2)ncc1C,[Pd],CCN(CC)CC,,,,test
US20080214529A1,CI.COC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1>>COC(=O)C1(C)CCCN1C(=O)OCc1ccccc1,,C1CCOC1,,Cl,CC(C)[N-]C(C)C.[Li+],test
US20100324086A1,Nc1cccc(C(=O)Nc2ccc(Br)cn2)c1.O=C(Cl)c1ccccc1C(F)(F)F>>O=C(Nc1ccc(Br)cn1)c1cccc(NCc2ccccc2C(F)(F)F)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20130053386A1,CC(C)(C)OC(=O)NC1(c2cccc(-c3cc(Oc4ccc(C(F)(F)F)cc4)n(Cc4cocn4)n3)c2)COC1>>NC1(c2cccc(-c3cc(Oc4ccc(C(F)(F)F)cc4)n(Cc4cocn4)n3)c2)COC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140309220A1,COC(=O)c1ccc(OC(C)C)c(Cl)n1.C[O-]>>COc1nc(C(=O)O)ccc1OC(C)C,,C1COCCO1,Cl,O,,test
US05449686,O=Cc1ccc(OC(F)F)c(OC(F)F)c1>>OCc1ccc(OC(F)F)c(OC(F)F)c1,,CCO,,[Na+].[OH-],,test
US05151550,CC1CC(C)(C)C=CC1=O.ClCc1ccc(Cl)cc1>>CC1CC(C)(C)C=CC1(O)Cc1ccc(Cl)cc1,,CCOCC,,[Mg],[Cl-].[NH4+],test
US20120081482A1,N.O=C1NC(=O)c2c(Cl)ccc(Cl)c21>>NC(=O)c1c(Cl)ccc(Cl)c1C(N)=O,,c1ccncc1,,,,test
US20070161615A1,CC(C)(C)OC(=O)/N=C(/NC(=O)OC(C)(C)C)n1cccn1.Nc1ccc(N2CCC[C@@H]2C(=O)NC2CC2)cc1>>CC(C)(C)OC(=O)/N=C(/NC(=O)OC(C)(C)C)Nc1ccc(N2CCC[C@@H]2C(=O)NC2CC2)cc1,,ClCCl,,,,test
US20140248263A1,C#CCOC[C@@H](O)COc1ccc(C(C)(C)c2ccc(O)cc2)cc1.Cc1ccc(S(=O)(=O)OC[C@@H]2CO2)cc1>>C#CCOC[C@@H](O)COc1ccc(C(C)(C)c2ccc(OC[C@@H]3CO3)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090286812A1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.CN(C)C=O.Cc1nc(-n2cncn2)ccc1N>>Cc1nc(-n2cncn2)ccc1Oc1ncnc2c1cnn2C1CCN(C(=O)OC(C)(C)C)CC1,,CN(C)C=O,O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20110065681A1,Cc1ccc(S(=O)(=O)Cl)cc1.OC[C@H](O)c1ccc(C(F)(F)F)nc1>>Cc1ccc(S(=O)(=O)OC[C@H](O)c2ccc(C(F)(F)F)nc2)cc1,,ClCCl,,c1ccncc1,,test
US20040224997A1,COC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(-c2ccc(N)cc2)cc1.Fc1ccc2sc(Cl)nc2c1>>O=C(c1ccc(-c2ccc(Nc3nc4cc(F)ccc4s3)cc2)cc1)[C@@H]1CCC[C@H]1C(=O)O,,CCCCO,,C1COCCO1,Cl,test
US20130035414A1,C=CC(=O)Cl.OC(CCc1ccccc1)CCc1ccccc1>>C=CC(=O)OC(CCc1ccccc1)CCc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,CO,test
US06689922B1,CC(C)(O)CCCCCc1ccc(C=Cc2cc(O)cc(O)c2)cc1>>CC(C)(O)CCCCCc1ccc(CCc2cc(O)cc(O)c2)cc1,[Pd],,,,,test
US20090093483A1,CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2ccc(Br)cc2C(C)(C)C1=O.OB(O)c1cccnc1>>CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2ccc(-c3cccnc3)cc2C(C)(C)C1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20140163012A1,CC(C)(C)OC(=O)N1CCCc2oc3cc(N4CCN(CCc5ccc(F)cn5)CC4=O)ccc3c2C1>>O=C1CN(CCc2ccc(F)cn2)CCN1c1ccc2c3c(oc2c1)CCCNC3,,CCOCC,CO,Cl,O=C([O-])O.[Na+],test
US05436140,C=[N+]=[N-].COCOc1ccc(C(O)[C@@H](C(=O)O)N(C)Sc2ccccc2[N+](=O)[O-])cc1>>COCOc1ccc(C(O)[C@@H](C(=O)OC)N(C)Sc2ccccc2[N+](=O)[O-])cc1,,CCOC(C)=O,CCOCC,,,test
US20140155389A1,CC(C)(C)OC(=O)N1CCNCC1.N#Cc1cc(Br)ccc1[N+](=O)[O-]>>CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)[O-])c(C#N)c2)CC1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20040147588A1,CCOc1cc(C(CS(C)(=O)=O)N2C(=O)c3cccc(C#N)c3C2=O)ccc1OC.Cl>>CCOc1cc(C(CS(C)(=O)=O)N2C(=O)c3cccc(CN)c3C2=O)ccc1OC.Cl,[Pd],CCO,CO,O,[H][H],test
US20120190635A1,CC(=O)OC1C(F)OC(C)CC1N(C)C.OC1CCCCCCCCCCCCC1>>CC(=O)OC1C(OC2CCCCCCCCCCCCC2)OC(C)CC1N(C)C,,CCOC(C)=O,,CCOCC,FB(F)F,test
US20140221417A1,CCOC(=O)Cc1c(CBr)n(C(C)=O)c2ccccc12.COc1ccc(N(C)C(=O)[C@H](Cc2cccc(SC(C)=O)c2)NC(=O)OC(C)(C)C)cc1>>CCOC(=O)Cc1c(CSc2cccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)N(C)c3ccc(OC)cc3)c2)[nH]c2ccccc12,,CCO,,Cl,[K+].[OH-],test
US20110166143A1,CN(C)/C=C/C(=O)c1cnn(-c2cccnc2)c1.NN>>c1cncc(-n2cc(-c3cc[nH]n3)cn2)c1,,CCO,,,,test
US05541229,CCC(C)Cc1nc2cc3ccccc3cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCC(C)Cc1nc2cc3ccccc3cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04785019,Cc1ccccc1C(=O)NCC#N.ClSC(Cl)(Cl)Cl>>Cc1ccccc1C(=O)N(CC#N)SC(Cl)(Cl)Cl,,ClCCl,,CCN(CC)CC,,test
US20110105483A1,CC(C)c1cc(-c2nnc(Cn3ccnc3)n2-c2ccc3c(ccn3C)c2)c(OCc2ccccc2)cc1OCc1ccccc1>>CC(C)c1cc(-c2nnc(Cn3ccnc3)n2-c2ccc3c(ccn3C)c2)c(O)cc1O,[Pd],CCO,,,,test
US20060135609A1,CC(C)(C)[Si](C)(C)OC(O)[C@@](O)(O[Si](C)(C)C(C)(C)C)[C@](O)(O[Si](C)(C)C(C)(C)C)C(O)OCc1ccccc1>>CC(C)(C)[Si](C)(C)OC(O)[C@@](O)(O[Si](C)(C)C(C)(C)C)[C@@](O)(CO)O[Si](C)(C)C(C)(C)C,[Pd],CCOC(C)=O,,,,test
US20110190263A1,CCc1cnc(N2CCC(CCCOc3ccc(COS(C)(=O)=O)c(CCOS(C)(=O)=O)n3)CC2)nc1.N>>CCc1cnc(N2CCC(CCCOc3ccc4c(n3)CCNC4)CC2)nc1,,CC(C)O,,,,test
US20160244450A1,COc1cc(OC)c(F)c(N2Cc3cnc(C4=CCCN(C(=O)OC(C)(C)C)C4)cc3CC2=O)c1F>>COc1cc(OC)c(F)c(N2Cc3cnc(C4CCCN(C(=O)OC(C)(C)C)C4)cc3CC2=O)c1F,[Pd],CO,,,,test
US04308384,CCCC(=O)NC(C)C(=O)C(=O)OCC.N=C(N)NN>>CCCC(=O)NC(C)c1n[nH]c(N)nc1=O,,CCO,,O=C(O)O,,test
US04681883,Clc1nc2ccccc2s1.NCCCCCOc1cccc(CN2CCCCC2)c1>>c1cc(CN2CCCCC2)cc(OCCCCCNc2nc3ccccc3s2)c1,,CCOC(C)=O,,,,test
US20130018030A1,C[C@@]1(C2CCNCC2)Cc2cc(C3=CCN(S(C)(=O)=O)CC3)ncc2O1.Clc1cnc(Cl)nc1>>C[C@@]1(C2CCN(c3ncc(Cl)cn3)CC2)Cc2cc(C3=CCN(S(C)(=O)=O)CC3)ncc2O1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100261699A1,COCCl.Cn1ccc(NC(=O)c2nc(Cl)ccc2Sc2ccc(O)cc2)n1>>COCOc1ccc(Sc2ccc(Cl)nc2C(=O)Nc2ccn(C)n2)cc1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,,test
US20060135578A1,CCOC(=O)Cc1cccc(-c2nc(COc3ccc(COc4nn(-c5ccccc5)cc4C=O)cc3OCC)c(C)o2)c1.CCOP(=O)(CP(=O)(OCC)OCC)OCC>>CCOC(=O)Cc1cccc(-c2nc(COc3ccc(COc4nn(-c5ccccc5)cc4/C=C/P(=O)(OCC)OCC)cc3OC)c(C)o2)c1,,O,,CN(C)C=O,[H-].[Na+],test
US05015740,Cc1nc2n(c(=O)c1CCBr)CCS2.ON=C(c1ccc(F)cc1F)N1CCNCC1>>Cc1nc2n(c(=O)c1CCN1CCN(C(=NO)c3ccc(F)cc3F)CC1)CCS2,,CC(=O)CC(C)C,,Br,O=C([O-])O.[Na+],test
US05013744,CC(C)(C)c1ccc(C#C[Si](C)(C)C)cc1>>C#Cc1ccc(C(C)(C)C)cc1,,CC(C)O,,[K+].[OH-],,test
US20120214791A1,BrBr.CC(=O)c1cnn(C)c1-c1ccc(C)cc1>>Cc1ccc(-c2c(C(=O)CBr)cnn2C)cc1,,CC(=O)O,,,,test
US20130053397A1,COC(=O)c1cc(-c2nnn[nH]2)cc2c1c(C)cn2C(C)C>>Cc1cn(C(C)C)c2cc(-c3nnn[nH]3)cc(C(=O)O)c12,,C1CCOC1,CO,[Na+].[OH-],,test
US07320993B1,O=C1c2ccccc2C(=O)N1CCCCBr.c1ccc(C2CNCCc3ccccc32)cc1>>O=C1c2ccccc2C(=O)N1CCCCN1CCc2ccccc2C(c2ccccc2)C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06166016,CCCCC(=O)Cl.COC(=O)c1sccc1N>>CCCCC(=O)Nc1ccsc1C(=O)OC,,c1ccncc1,,,,test
US20070265472A1,CC(C)c1ccccc1O.COCCl>>COCOc1ccccc1C(C)C,,C1CCOC1,O,CO,[H-].[Na+],test
US20090264403A1,CC(=O)OC1Cc2cc(OC[C@H]3CCCO3)ccc2C1=O>>O=C1c2ccc(OC[C@H]3CCCO3)cc2CC1O,,CO,,O,O=C([O-])[O-].[K+].[K+],test
US20040152690A1,FC(F)(F)c1cc(Br)cnc1N1CCNCC1.O=C(Cl)OCc1ccccc1>>O=C(OCc1ccccc1)N1CCN(c2ncc(Br)cc2C(F)(F)F)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20020183319A1,Cc1c(C(=O)N2CCN(C)CC2)c[nH]c1C=O.O=C1Cc2c(ncnc2Nc2ccc(F)c(Cl)c2)N1>>Cc1c(C(=O)N2CCN(C)CC2)c[nH]c1C=C1C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c21,C1CCNCC1,CCO,,,,test
US04937373,BrCCCCCCc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1.CCOC(=O)[C@@H](C)c1ccc2cc(O)ccc2c1>>CCOC(=O)[C@@H](C)c1ccc2cc(OCCCCCCc3ccc(OCc4ccccc4)c(OCc4ccccc4)c3)ccc2c1,,CC(C)=O,CN(C)C=O,[I-].[K+],O=C([O-])O.[Na+],test
US20100076027A1,CCOC(=O)c1ccc(NC(=O)C(c2c3ccccc3nn2-c2ccc(Cl)cc2)C2CCCCC2)c(F)c1>>O=C(O)c1ccc(NC(=O)C(c2c3ccccc3nn2-c2ccc(Cl)cc2)C2CCCCC2)c(F)c1,,C1CCOC1,CO,[Li+].[OH-],,test
US20040229861A1,CCN1C[C@H](c2cccc(F)c2F)CC[C@@H](N)C1=O.N#CN=C(Oc1ccccc1)Oc1ccccc1>>CCN1C[C@H](c2cccc(F)c2F)CC[C@@H](NC(=NC#N)Oc2ccccc2)C1=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04859684,CCOC(C)=N.Nc1ccc(C(=O)c2cccc(F)c2)cc1N>>Cc1nc2cc(C=O)ccc2[nH]1,,CO,,Cl,,test
US20150011546A1,CI.Cc1cc2ccccc2n1C(C)(C)CO>>COCC(C)(C)n1c(C)cc2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US05273974,CC(=O)N1CCC(CCC(=O)c2ccc3c(c2)CCN3)CC1.CCI>>CCN1CCc2cc(C(=O)CCC3CCN(C(C)=O)CC3)ccc21,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20030170858A1,Cc1nc(-c2ccccc2)oc1-c1cc(CNC(=O)OC(C)(C)C)[nH]n1>>Cc1nc(-c2ccccc2)oc1-c1cc(CN)[nH]n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04822805,CC(=NO)C(=O)c1ccncc1.COc1ccc(C=O)c(OC)c1.N>>COc1ccc(-c2nc(-c3ccncc3)c(C)n2O)c(OC)c1,,C1COCCO1,CCO,O,,test
US20030225283A1,COC(=O)C(CC1CCC(=O)C1)c1ccc(S(C)(=O)=O)c(Cl)c1>>CS(=O)(=O)c1ccc(C(CC2CCC(=O)C2)C(=O)O)cc1Cl,,CO,,[Na+].[OH-],,test
US20080293767A1,C1CCC2(CC1)CO2.Cc1c(Cl)cc(C(=O)NCC2CCNCC2)c(=O)n1C(C)C>>Cc1c(Cl)cc(C(=O)NCC2CCN(CC3(O)CCCCC3)CC2)c(=O)n1C(C)C,,CO,,,,test
US20060293352A1,BrCc1ccccc1.Oc1cc(C(F)(F)F)ccc1F>>Fc1ccc(C(F)(F)F)cc1OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100267712A1,CN(C)/C=N/c1ccc2c(ccn2C)n1>>Cn1ccc2nc(N)ccc21,,CO,,[Na+].[OH-],,test
US20130197026A1,Cc1ccc(S(=O)(=O)c2cc3ccccc3n2CCCCBr)cc1>>c1ccc2c(c1)cc1n2CCCC1,,Cc1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,CCCC[SnH](CCCC)CCCC,test
US20140256736A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1noc2ccc(O)cc12.COc1ccc(CN(c2ncns2)S(=O)(=O)c2cc(F)c(F)cc2F)c(OC)c1>>COc1ccc(CN(c2ncns2)S(=O)(=O)c2cc(F)c(Oc3ccc4onc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c4c3)cc2F)c(OC)c1,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20130029969A1,ClCCBr.N#CCc1cccs1>>N#CC1(c2cccs2)CC1,,CS(C)=O,,O,[H-].[Na+],test
US20140228343A1,CC(C)(C)OC(=O)N1CC(Nc2cc(Br)ccc2[N+](=O)[O-])C1>>CC(C)(C)OC(=O)N1CC(Nc2cc(Br)ccc2N)C1,[Fe],CCO,,[Cl-].[NH4+],,test
US04055663,CNCC(=O)O.O=C(Cl)CCl>>CN(CC(=O)O)C(=O)CCl,,CCOC(C)=O,,,,test
US05068325,Fc1ccccc1C=CCCl.Nc1nc2c(s1)CCNCC2>>Nc1nc2c(s1)CCN(CC=Cc1ccccc1F)CC2,,ClC(Cl)Cl,,CCOCC,,test
US06245746B1,C=CC#N.NCCCc1ccccc1>>N#CCCNCCCc1ccccc1,,CCO,,,,test
US20040248887A1,C[C@@H](CO)NC(=O)Cc1ccccc1>>C[C@@H](C=O)NC(=O)Cc1ccccc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US06458830B1,FC(F)(F)c1cc(C2CO2)cc(C(F)(F)F)c1.OCc1ccccc1>>OC(COCc1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,C1CCOC1,,[H-].[Na+],,test
US20060293307A1,CC(=O)NC[C@H]1CN(c2ccc(N3CCNCC3)c(F)c2)C(=O)O1.O=[N+]([O-])c1ccc(Br)s1>>CC(=O)NC[C@H]1CN(c2ccc(N3CCN(c4ccc([N+](=O)[O-])s4)CC3)c(F)c2)C(=O)O1,,CC#N,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US05330987,CCCC(=O)Nc1ccc(Cl)nc1C#N>>CCCc1nc2ccc(Cl)nc2c(=O)[nH]1,,CO,O,CC(=O)O,[Na+].[OH-],test
US20090062277A1,CC(C)(O)C1CCNCC1.Fc1ncc(Cl)cc1C(F)F>>CC(C)(O)C1CCN(c2ncc(Cl)cc2C(F)F)CC1,,CS(C)=O,ClCCl,,,test
US20120010189A1,Cc1cc(OC2CN(C(=O)OC(C)(C)C)C2)ccc1CN(C)C>>Cc1cc(OC2CNC2)ccc1CN(C)C,,CO,,Cl,,test
US09309263B2,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc([N+](=O)[O-])ccc2F)[C@H](CCO)S(=O)(=O)C1(C)C>>CC(C)(C)OC(=O)NC1=N[C@]2(C)c3cc([N+](=O)[O-])ccc3OCCC2S(=O)(=O)C1(C)C,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US05491173,N.OCC/C(=C(\c1ccccc1)c1ccc(OCCBr)cc1)c1ccccc1>>NCCOc1ccc(/C(=C(/CCO)c2ccccc2)c2ccccc2)cc1,,CCO,,,,test
US20070004704A1,BrC(Br)(Br)Br.Cc1oc(-c2ccccc2)nc1COc1ccc(CO)cc1>>Cc1oc(-c2ccccc2)nc1COc1ccc(CBr)cc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20120277208A1,CC(C)Oc1cc(O)cc(C(=O)Nc2ccn(C)n2)c1.N#Cc1cnc(Cl)cn1>>CC(C)Oc1cc(Oc2cnc(C#N)cn2)cc(C(=O)Nc2ccn(C)n2)c1,,CN1CCCC1=O,O,CCOCC,O=C([O-])[O-].[K+].[K+],test
US20100256188A1,CCOC(=O)c1cc2[nH]c(Nc3cc(CNC(=O)C(C)(C)C)ccc3Cl)nc2cc1Cl>>CC(C)(C)C(=O)NCc1ccc(Cl)c(Nc2nc3cc(Cl)c(C(=O)O)cc3[nH]2)c1,,CCO,,[Na+].[OH-],,test
US06217793B1,CCCCCCCC[C@H](C)C(=O)Oc1ccc(OC(=O)c2ccc(OCc3ccccc3)cc2)cc1>>CCCCCCCC[C@H](C)C(=O)Oc1ccc(OC(=O)c2ccc(O)cc2)cc1,[Pd],CCOC(C)=O,,,,test
US20100137273A1,CC(C)(C)OC(=O)COc1ccc([C@@H]2[C@@H](SSc3ncccc3[N+](=O)[O-])C(=O)N2c2ccc(F)cc2)cc1.O=C(CCl)c1ccc2c(c1)CCO2>>O=C(O)COc1ccc([C@@H]2[C@@H](SCC(=O)c3ccc4c(c3)CCO4)C(=O)N2c2ccc(F)cc2)cc1,,CC(C)=O,O,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140336190A1,Br[Mg]C1CC1.Cc1noc(C)c1-c1cc(C(=O)c2ccccn2)c2nc(C3CC3)[nH]c2c1>>Cc1noc(C)c1-c1cc(C(O)(c2ccccn2)C2CC2)c2nc(C3CC3)[nH]c2c1,,C1CCOC1,,,,test
US20150322008A1,COC(=O)c1cc(Cl)c(NC(C)=O)cc1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1cc(Cl)c(NC(C)=O)cc1OS(=O)(=O)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US05185446,CCOC(=O)C1CCc2[nH]c(=O)n3cc(-c4ccccc4F)nc3c2C1>>O=C(O)C1CCc2[nH]c(=O)n3cc(-c4ccccc4F)nc3c2C1,,[Na+],[OH-],Cl,,test
US20040082611A1,O=C=O.[Li]CCCC.c1cncc(-c2cncs2)c1>>O=C([O-])c1ncc(-c2cccnc2)s1.[Li+],,CCOCC,,CCCCCC,,test
US20070244132A1,CN(C(=O)C(F)(F)F)c1c(I)ncnc1I.N#Cc1cccc(Oc2ccc(N)cc2Cl)c1>>CN(C(=O)C(F)(F)F)c1c(I)ncnc1Nc1ccc(Oc2cccc(C#N)c2)c(Cl)c1,,CN1CCCC1=O,,O=C([O-])O.[Na+],,test
US20140051676A1,CCOC(=O)c1ccc(Cl)nc1.OC1CCOCC1>>CCOC(=O)c1ccc(OC2CCOCC2)nc1,,C1CCOC1,,O,CC(C)(C)[O-].[K+],test
US20040122244A1,COC1=C(OC)C(=O)C(Cc2ccc(OCc3cccnc3)c(C(=O)O)c2)=C(C)C1=O.Nc1ccncc1>>COC1=C(OC)C(=O)C(Cc2ccc(OCc3cccnc3)c(C(=O)Nc3ccncc3)c2)=C(C)C1=O,,ClCCl,,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US04728650,COc1c(C)c(C)c2c(c1C)CCC(C)(CCN1CCN(CC=C(C)C)CC1)O2>>COc1c(C)c(C)c2c(c1C)CCC(C)(CCN1CCN(CCC(C)C)CC1)O2,[Pd],CCO,,,,test
US20120034270A1,Ic1ccc2c(c1)CN(C(c1ccccc1)(c1ccccc1)c1ccccc1)C2.O=C(O)C(F)(F)F>>Ic1ccc2c(c1)CNC2.O=C(O)C(F)(F)F,,CCO,,ClCCl,,test
US20100168418A1,BrCCOc1ccccc1.CCOC(=O)C1(CCCn2c(=O)ccc3ccc(OC)cc32)CCNCC1>>CCOC(=O)C1(CCCn2c(=O)ccc3ccc(OC)cc32)CCN(CCOc2ccccc2)CC1,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080021022A1,COc1ccc(-c2nocc2C(=O)O)cc1Cl.Cc1ccccc1C1(O)CNC(C)C1>>COc1ccc(-c2nocc2C(=O)N2CC(O)(c3ccccc3C)CC2C)cc1Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20150133451A1,CC(=O)c1cccc(C(=O)Nc2cn(C)nc2N2CCC(C)(C)C2=O)n1.CCOC(C)=O>>Cn1cc(NC(=O)c2cccc(C(C)(C)O)n2)c(N2CCC(C)(C)C2=O)n1,,CCOC(C)=O,O,C1CCOC1,,test
US05409943,CCOC(=N)Cc1ccccc1C.COc1ccc(COc2cccnc2N)cc1>>COc1ccc(COc2cccnc2NC(=N)Cc2ccccc2C)cc1,,CCO,ClC(Cl)Cl,Cl,,test
US20110269751A1,O=CCCCC=O.O=[N+]([O-])C=C1NCCN1CC1CCOC1>>O=[N+]([O-])C1=C2N(CC3CCOC3)CCN2C2CCCC1O2,,CC#N,,Cl,,test
US20090093417A1,BrCc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1.CCCCCN>>CCCCCNCc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US05260310,COC(=O)C(OC)C(=O)[O-].N>>COC(C(N)=O)C(=O)O,,ClCCl,,,,test
US20100016343A1,COc1ccc(B(O)O)cc1.O=C(NCCCCN1CCCCC1)Nc1ccc(Br)nc1>>COc1ccc(-c2ccc(NC(=O)NCCCCN3CCCCC3)cn2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20080146637A1,CC(C)(C)N.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1Br>>CC(C)(C)NS(=O)(=O)c1ccc(C(F)(F)F)cc1Br,,ClCCl,,,,test
US20090042852A1,CCOC(=O)c1cc(C#N)c(N2CCCNCC2)nc1C.O=C(NS(=O)(=O)c1ccc(Cl)s1)OCC(Cl)(Cl)Cl>>CCOC(=O)c1cc(C#N)c(N2CCCN(C(=O)NS(=O)(=O)c3ccc(Cl)s3)CC2)nc1C,CN(C)c1ccncc1,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,,test
US20060178377A1,C1CSCCN1.COC(=O)c1c(C)nc2nc(Br)nn2c1-c1ccc(Cl)cc1Cl>>COC(=O)c1c(C)nc2nc(N3CCSCC3)nn2c1-c1ccc(Cl)cc1Cl,,C1COCCO1,,,,test
US20150018363A1,Clc1ccc(CBr)cc1.O=c1cc(O)cnn1C1CCCCO1>>O=c1cc(OCc2ccc(Cl)cc2)cnn1C1CCCCO1,,CN(C)C=O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20150266821A1,C[Si](C)(C)OC1(C(F)(F)F)CCCc2c1[nH]c1c(Cl)cc(Cl)cc21>>OC1(C(F)(F)F)CCCc2c1[nH]c1c(Cl)cc(Cl)cc21,,C1CCOC1,O,[K+].[OH-],,test
US20030186969A1,CC(C)O.O=C(c1ccc(CN2C(=O)CN(C(=O)c3ccc(Cl)cc3)Cc3ccc(O)cc32)cc1)N1CC=CC1>>CC(C)Oc1ccc2c(c1)N(Cc1ccc(C(=O)N3CC=CC3)cc1)C(=O)CN(C(=O)c1ccc(Cl)cc1)C2,,C1CCOC1,CCOC(C)=O,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04081452,NN.O=C1c2ccccc2C(=O)N1OCc1nnc2n1-c1ccc(C(F)(F)F)cc1C(c1ccccc1Cl)=NC2>>C1=Cc2ccccc2NN=C1,,CCO,,O,,test
US05272171,O=C(c1ncc[nH]1)c1ncc[nH]1.O=P(OCCCCO)(OCc1ccccc1)OCc1ccccc1>>O=C(OCCCCOP(=O)(OCc1ccccc1)OCc1ccccc1)n1ccnc1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20120040949A1,CC(=O)OCc1c(-c2cc(Nc3ccc(C(=O)N4CCC(C)(O)CC4)cn3)c(=O)n(C)n2)cccc1-n1ncc2cc(C(C)(C)C)cc(F)c2c1=O>>Cn1nc(-c2cccc(-n3ncc4cc(C(C)(C)C)cc(F)c4c3=O)c2CO)cc(Nc2ccc(C(=O)N3CCC(C)(O)CC3)cn2)c1=O,,C1COCCO1,,[Li+].[OH-],,test
US20160068513A1,CC(C)c1cc(Nc2nc(Cl)nc3c2CCC3)n[nH]1.COC(=O)[C@@H]1C=CCN1>>COC(=O)[C@@H]1C=CCN1c1nc2c(c(Nc3cc(C(C)C)[nH]n3)n1)CCC2,,CO,,Cl,O=C(O)C(F)(F)F,test
US20080009488A1,Nc1ccc(C(=O)c2ccccc2C(=O)OCc2ccccc2)cc1[N+](=O)[O-]>>Nc1ccc(C(=O)c2ccccc2C(=O)OCc2ccccc2)cc1N,[Fe],C1CCOC1,O,O=C[O-].[NH4+],,test
US20030199562A1,COc1ccc(OC)c(NC(=O)c2cc(OC)ccc2OC)c1>>Oc1ccc(O)c(-c2nc3cc(O)ccc3o2)c1,,Cl,,c1ccncc1,,test
US20100280062A1,CCC(=C1c2ccc(F)cc2OCc2ncccc21)c1cccc([N+](=O)[O-])c1>>CCC(=C1C2=CC=CNC2=COc2cc(F)ccc21)c1cccc(N)c1,,CCO,,,,test
US20090298815A1,CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3cc(F)ccc3F)c2F)c(-c2ccnc(Cl)n2)s1>>CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3cc(F)ccc3F)c2F)c(-c2ccncn2)s1,[Pd],CCO,CO,,,test
US20120288492A1,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.CSc1cnc(Cl)nc1N1CCOCC1>>CSc1cnc(-c2ccc(N)cc2)nc1N1CCOCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,O,C1COCCO1,O=C([O-])O.[Na+],test
US20160102071A1,CCOC(=O)CCc1ccc(COc2ccc3scc(-c4ccccc4C)c3c2)cc1>>Cc1ccccc1-c1csc2ccc(OCc3ccc(CCC(=O)O)cc3)cc12,,CCO,,Cl,[Li+].[OH-],test
US20100069381A1,CI.Cc1nnc(-c2ccc3occ(-c4ccc(CO)cc4)c3c2)o1>>COCc1ccc(-c2coc3ccc(-c4nnc(C)o4)cc23)cc1,,CCOC(C)=O,CN(C)C=O,C1CCOC1,[H-].[Na+],test
US06908915B1,O=C(Cl)CCCl.O=C1Nc2ccccc2Nc2ccccc21>>O=C1Nc2ccccc2N(C(=O)CCCl)c2ccccc21,,C1CCOC1,,,,test
US20020191824A1,CC(=O)Oc1ccc2c(c1)Oc1cc(OC(C)=O)ccc1C21OC(=O)c2ccccc21>>O=C(O)c1ccccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12,,CS(C)=O,,,,test
US20070117854A1,BrBr.FC(F)(F)C(F)(F)c1cc[nH]n1>>FC(F)(F)C(F)(F)c1n[nH]cc1Br,,O,,[Na+].[OH-],,test
US20080132477A1,C=CCOc1cc(C(=O)NCC(OC)OC)cc(C(=O)OC)c1>>C=CCOc1cc(C(=O)NCC=O)cc(C(=O)OC)c1,,C1CCOC1,Cl,,,test
US20040132769A1,CCOC(=O)Nc1cc2ccccc2cc1Cl>>Nc1cc2ccccc2cc1Cl,,CCO,,[K+].[OH-],,test
US04367238,COS(=O)(=O)OC.Cc1ccccc1Sc1cccc(CO)c1O>>COc1c(CO)cccc1Sc1ccccc1C,,O,,[K+].[OH-],,test
US04665169,CC(=O)SC1CC[S+](C)CC1.O=S(=O)([O-])C(F)(F)F>>C[S+]1CCC(S)CC1.O=S(=O)([O-])C(F)(F)F,,O,,Cl,[Na+].[OH-],test
US20060173018A1,Cc1ccc2c(N3CC[C@@H](NC(=O)OCc4ccccc4)C3)nc(-c3ccccc3O)nc2c1.Cl>>Cc1ccc2c(N3CC[C@@H](NC(=O)OCc4ccccc4)C3)nc(-c3ccccc3O)nc2c1.Cl,,ClCCl,,CCOCC,,test
US20090306139A1,CCOC(=O)C1CNCC(c2ccc(C(C)C)cc2)C1.O=C(Cl)C1CCCC1>>CCOC(=O)C1CC(c2ccc(C(C)C)cc2)CN(C(=O)C2CCCC2)C1,,ClCCl,,CCN(CC)CC,,test
US09333205B2,CCOC(=O)C1=NOC2(O)C(OCC)=CCCC12>>CCOC(=O)c1noc2c1CCCC2=O,,CCO,Cl,,,test
US20120157494A1,COCC(C)N1Cc2c(cccc2[N+](=O)[O-])C1=O>>COCC(C)N1Cc2c(N)cccc2C1=O,[Pd],CO,,[H][H],,test
US20120245144A1,COC(=O)C1(Oc2ccc3c(c2)OCCn2cc(-c4nc(C)nn4C(C)C)nc2-3)CC1>>Cc1nc(-c2cn3c(n2)-c2ccc(OC4(C(=O)O)CC4)cc2OCC3)n(C(C)C)n1,,CO,O,[Li+].[OH-],,test
US04374843,Br.N=C(N)Nc1nc(C(=O)CBr)cs1.NC=S>>Br.Br.N=C(N)Nc1nc(-c2cscn2)cs1,,CN(C)C=O,,,,test
US20140045936A1,C=C/C=C/c1ccccc1.COC(=O)C(=[N+]=[N-])c1ccc(-c2ccccc2)cc1>>COC(=O)C1(c2ccc(-c3ccccc3)cc2)CC1/C=C/c1ccccc1,,Cc1ccccc1,,,,test
US20110152273A1,COC(=O)c1c(C#N)nc(N2CCCCC2CNC(=O)OC(C)(C)C)nc1Nc1cccc(C)c1>>Cc1cccc(Nc2nc(N3CCCCC3CNC(=O)OC(C)(C)C)nc3c2C(=O)NC3)c1,[Pd],CCO,,Cl,,test
US20030065179A1,CC(=O)O[C@H](C)c1nccc(Cl)n1.c1ccc2nc(N3CCNCC3)cnc2c1>>CC(=O)O[C@H](C)c1nccc(N2CCN(c3cnc4ccccc4n3)CC2)n1,,CC(C)O,,CCN(CC)CC,,test
US20100197682A1,O=C(Cl)C(=O)Cl.O=C(O)c1cncc(Br)c1>>O=C(Cl)c1cncc(Br)c1,,CN(C)C=O,,[H-].[Na+],,test
USRE036187,CO.N#Cc1cn(COCCO)c2ncnc(N)c12>>COC(=N)c1cn(COCCO)c2ncnc(N)c12,,CO,,C[O-].[Na+],,test
US20150152065A1,Cc1ccc(C)c(Cn2c(S(=O)c3ccccc3)nc3ccccc32)c1.O=C(OO)c1cccc(Cl)c1>>Cc1ccc(C)c(Cn2c(S(=O)(=O)c3ccccc3)nc3ccccc32)c1,,ClCCl,,,,test
US20040132727A1,COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OCc1ccc(F)cc1>>COc1cc2ncnc(Oc3ccc(NC(=O)OCc4ccc(F)cc4)cc3)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US03984407,NCCCC1CCC2=C1CC=CC2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NCCCC1CCC2=C1CC=CC2)C(F)(F)F,,CCOCC,,O=C([O-])[O-].[Na+].[Na+],,test
US20070105891A1,CC(C)OB(OC(C)C)OC(C)C.Cc1nc2c(Cl)ncc(I)c2s1>>Cc1nc2c(Cl)ncc(B(O)O)c2s1,,C1CCOC1,,Cl,[Li]CCCC,test
US20080234237A1,CN(C)CCCl.O=C1CCc2cc([N+](=O)[O-])ccc2N1>>CN(C)CCN1C(=O)CCc2cc([N+](=O)[O-])ccc21,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US05739129,COc1ccc(N(C(=O)CN2C(=O)C(N=[N+]=[N-])C(=O)N(c3cccnc3)c3cc(F)ccc32)C(C)C)cc1>>COc1ccc(N(C(=O)CN2C(=O)C(N)C(=O)N(c3cccnc3)c3cc(F)ccc32)C(C)C)cc1,[Pd],CCOC(C)=O,,[H][H],,test
US20100135999A1,CCCCOC(=O)N1CCN(C(=O)[C@H](CCc2nn[nH]n2)NC(=O)OC(C)(C)C)CC1>>CCCCOC(=O)N1CCN(C(=O)[C@@H](N)CCc2nn[nH]n2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04169720,COC(=O)C(C)Oc1ccc(COc2ccc(Cl)cc2)cc1.OCCOc1cc(Cl)c(Cl)cc1Cl>>CC(Oc1ccc(COc2ccc(Cl)cc2)cc1)C(=O)OCCOc1cc(Cl)c(Cl)cc1Cl,,CC(C)=O,,[Na],,test
US20030236287A1,CC[C@@H](C)O.O=[N+]([O-])c1ccc(F)cc1>>CC[C@@H](C)Oc1ccc([N+](=O)[O-])cc1,,CN(C)C=O,O,[H-].[Na+],,test
US20160194290A1,COC(=O)C(C)c1ccc(O)cc1.O=C1CCC(=O)N1Cl>>COC(=O)C(C)c1ccc(O)c(Cl)c1,,CN(C)C=O,,O,,test
US06294532B1,COc1cc2c(=O)n(COC(=O)C(C)(C)C)cnc2cc1OCCn1ccnn1>>COc1cc2cncnc2cc1OCCn1ccnn1,,CO,,N,,test
US20150327551A1,CCOC(=O)CN1CCc2nn(-c3cccnc3)cc2C1=O>>O=C(O)CN1CCc2nn(-c3cccnc3)cc2C1=O,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20150291563A1,O=S(=O)(Cl)C1CC1.OC(C1=NN(c2cccc(C3=CCNCC3)c2)C(c2ccccc2Cl)C1)(C(F)(F)F)C(F)(F)F>>O=S(=O)(C1CC1)N1CC=C(c2cccc(N3N=C(C(O)(C(F)(F)F)C(F)(F)F)CC3c3ccccc3Cl)c2)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US04175127,COc1ccc(-c2nc(SC(C)C)[nH]c2-c2ccncc2)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(-c2nc(S(=O)C(C)C)[nH]c2-c2ccncc2)cc1,,ClCCl,,,,test
US04243678,CCOC(=O)CCCCCNc1ccccc1-c1ccccc1.COc1ccc(Cl)cc1C(=O)Cl>>CCOC(=O)CCCCCN(C(=O)c1cc(Cl)ccc1OC)c1ccccc1-c1ccccc1,,c1ccccc1,,CCN(C(C)C)C(C)C,,test
US20080096935A1,BrCc1cccnc1.CC1(C2CCCC2)Cc2cc(O)c(Cl)c(Cl)c2C1=O>>CC1(C2CCCC2)Cc2cc(OCc3cccnc3)c(Cl)c(Cl)c2C1=O,,CC(C)=O,,Br,O=C([O-])[O-].[K+].[K+],test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1-c1ccc2ccccc2c1>>CCCC(C(=O)O)c1c(C)nc(-c2ccccc2)nc1-c1ccc2ccccc2c1,,CO,,[Na+].[OH-],,test
US20040082607A1,CCCCOc1c(CNC(=O)OC(C)(C)C)n(CC(C)C)c(=O)c2ccc(-c3noc(=O)[nH]3)cc12.Cl>>CCCCOc1c(CN)n(CC(C)C)c(=O)c2ccc(-c3noc(=O)[nH]3)cc12.Cl,,CCOC(C)=O,,,,test
US20150299123A1,CCOC(=O)CCN.O=Cc1nc(Br)cs1>>CCOC(=O)CCNCc1nc(Br)cs1,,CCOC(C)=O,ClCCCl,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04018922,CC1(OCCO)CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1.CCCCCCCCCCCCCCCC(=O)Cl>>CCCCCCCCCCCCCCCC(=O)OCCOC1(C)CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1,,c1ccccc1,,CCN(CC)CC,,test
US20110288066A1,C/C=C/c1ccc(S(C)(=O)=O)cc1N>>CCCc1ccc(S(C)(=O)=O)cc1N,[Pd],CO,,[H][H],,test
US20090270402A1,CN=Cc1ccc2nnc(C(C)C)n2n1.[C-]#[N+]C(c1ccc(F)cc1F)S(=O)(=O)c1ccc(C)cc1>>CC(C)c1nnc2ccc(-c3c(-c4ccc(F)cc4F)ncn3C)nn12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06011174,C[C@H]([C@H](CCc1ccccc1)c1ccc(Oc2ccccc2)cc1)N(CC(=O)OC(C)(C)C)C(=O)[C@@H]1COC(C(=O)OCOC(=O)C(C)(C)C)(C(=O)OCOC(=O)C(C)(C)C)O1>>C[C@H]([C@H](CCc1ccccc1)c1ccc(Oc2ccccc2)cc1)N(CC(=O)O)C(=O)[C@@H]1COC(C(=O)OCOC(=O)C(C)(C)C)(C(=O)OCOC(=O)C(C)(C)C)O1,,O=CO,,,,test
US20150148327A1,CI.COc1ccc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)cn1>>Cn1cc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)ccc1=O,,CC#N,,[I-].[Na+],,test
US20140228343A1,CC(=O)Cl.NCc1ccc(Br)cn1>>CC(=O)NCc1ccc(Br)cn1,,ClCCl,,CCN(CC)CC,,test
US20120053168A1,CC(C)(C)OC(=O)N1CCc2cc(N)c(N)cc2CC1.OC1OCCOC1O>>CC(C)(C)OC(=O)N1CCc2cc3nccnc3cc2CC1,,O,,CC(C)O,,test
US20160237067A1,Cc1c(F)cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)cc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1.Cl>>Cc1c(F)cc(C(=O)NC2CCNCC2)cc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1.Cl,,C1COCCO1,,,,test
US04929637,COCCOCOC(C)c1sc(S(N)(=O)=O)cc1S(C)(=O)=O>>CC(O)c1sc(S(N)(=O)=O)cc1S(C)(=O)=O,,CO,O,O=S(=O)(O)O,,test
US20150246934A1,CN(C(=O)OC(C)(C)C)c1cc(F)cc2c1[nH]c1nc(S(=O)(=O)Cc3ccccc3)nc(S(=O)(=O)Cc3ccccc3)c12.CSc1ncc(O)cn1.SCc1ccccc1>>CSc1ncc(Oc2nc(SCc3ccccc3)c3c(n2)[nH]c2c(N(C)C(=O)OC(C)(C)C)cc(F)cc23)cn1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20150148311A1,O=C(Cl)C1(CCl)CC1.c1ccc2c(c1)NCCN2C1CC1>>O=C(N1CCN(C2CC2)c2ccccc21)C1(CCl)CC1,,ClCCl,,CCN(CC)CC,,test
US05665768,NO.O=C1C=C(c2ccc(Sc3ccc(F)cc3)o2)CC1>>ON=C1C=C(c2ccc(Sc3ccc(F)cc3)o2)CC1,,CCO,c1ccncc1,Cl,,test
US05658491,CCCCCCCCOc1cnc(-c2ccc(O)cc2)nc1.CCCCCCCCc1cnc(-c2ccc(OCCCOCC(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)OC(F)(F)F)cc2)nc1>>CCCCCCCCOc1cnc(-c2ccc(OCCCOCC(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)OC(F)(F)F)cc2)nc1,,CN(C)C=O,,,,test
US20140045906A1,CCCc1cc(C(=O)O)on1.C[C@@](CO)(C[C@H](N)Cc1ccc(-c2cc(Cl)ccc2F)cc1)C(=O)O>>CCCc1cc(C(=O)N[C@H](Cc2ccc(-c3cc(Cl)ccc3F)cc2)C[C@@](C)(CO)C(=O)O)on1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150087682A1,CCOc1ccc(O)cc1.ClCC1CO1>>CCOc1ccc(OCC2CO2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030036651A1,CCOC(=O)CCCc1cccs1.O=Cc1cccnc1Nc1cccc([N+](=O)[O-])c1>>O=c1c(CCc2cccs2)cc2cccnc2n1-c1cccc([N+](=O)[O-])c1,,CN(C)C=O,,CC(C)[N-]C(C)C.[Li+],,test
US20090181965A1,Cc1nc(C)c(-c2ccc(NC(N)=S)cc2)o1.O=C1C(Br)CCCC1c1ccccc1>>Cc1nc(C)c(-c2ccc(Nc3nc4c(s3)CCCC4c3ccccc3)cc2)o1,,CCO,,,,test
US20100216808A1,CC(=O)c1ccccc1N.Cn1nc(C(N)=O)c2c1-c1nc(I)ncc1CC2>>CC(=O)c1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130217579A1,C=C(CC(=O)OC)C(=O)OC.CC(C)CN>>COC(=O)C1CC(=O)N(CC(C)C)C1,,CO,,,,test
US04551455,Cc1nccn1-c1ccc(C2=NNC(=O)CC2C)cc1.O=C(O)/C=C/C(=O)O>>Cc1nccn1-c1ccc(C2=NNC(=O)CC2C)cc1.O=C(O)/C=C/C(=O)O,,CCO,,,,test
US20070225282A1,CC(C)(C)OC(=O)Nc1noc2ccc(CNC(=O)Cc3c(C#N)ccc(Cl)[n+]3[O-])cc12.NCC(F)(F)c1ccccn1>>N#Cc1ccc(NCC(F)(F)c2ccccn2)[n+]([O-])c1CC(=O)NCc1ccc2onc(N)c2c1,,CS(C)=O,,,,test
US05057517,CCc1nc(Cl)c([N+](=O)[O-])c(Cl)n1.NC1CC1>>CCc1nc(Cl)c(N)c(NC2CC2)n1,[Ni],CC(C)O,CCOC(C)=O,CO,[H][H],test
US05618811,Cc1ccccc1C1CCC(=O)CC1.O=S(=O)(Cl)Cl>>Cc1ccccc1C1CCC(=O)C(Cl)C1,,ClCCl,,O=C([O-])O.[Na+],,test
US20090143371A1,CCCCS(N)(=O)=O.Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)cn1>>CCCCS(=O)(=O)NC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1,CN(C)c1ccncc1,ClCCl,,,,test
US20070043064A1,CCN(C(C)=O)c1cccc(C(=O)C=CN(C)C)c1.Nc1[nH]ncc1[N+](=O)[O-]>>CCN(C(C)=O)c1cccc(-c2ccnc3c([N+](=O)[O-])cnn23)c1,,CC(=O)O,,CCOC(C)=O,,test
US20110076292A1,COC(=O)C(O)C(C)C.Oc1ccc2c(c1)OCCn1cc(-c3ncnn3CC(F)(F)F)nc1-2>>COC(=O)C(Oc1ccc2c(c1)OCCn1cc(-c3ncnn3CC(F)(F)F)nc1-2)C(C)C,,CCOC(C)=O,,CO,,test
US20130095193A1,CC(C)(C(=O)O)c1cc(I)ccn1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(C(=O)C(C)(C)c2cc(I)ccn2)CC1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20070287711A1,CN(C)C(=O)c1cc(-c2cnc3c(c2)c(Cc2ccc(N(C)C)cc2)nn3COC(=O)C(C)(C)C)ccc1N>>CN(C)C(=O)c1cc(-c2cnc3[nH]nc(Cc4ccc(N(C)C)cc4)c3c2)ccc1N,,C1CCOC1,CO,[Na+].[OH-],,test
US20120101136A1,BrCCCCBr.CC(C)Oc1ccc(-c2nc(-c3ccc(O)cc3Cl)no2)cc1C#N>>CC(C)Oc1ccc(-c2nc(-c3ccc(OCCCCBr)cc3Cl)no2)cc1C#N,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20150344727A1,CCCCCCCCCCCCCCCCN(C)C.CO.COC(=O)OC>>CCCCCCCCCCCCCCCC[N+](C)(C)C.COC(=O)[O-],,CO,,,,test
US20090247547A1,CCOC(=O)c1c(CC)nn2ccccc12>>CCc1nn2ccccc2c1CO,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US06326386B1,CC(C)(C)NC(=O)CCN(C(=O)c1cc(Cl)cc(OCCN(C(=O)OC(C)(C)C)c2ccncc2)c1)C1CCC1.O=C(O)C(F)(F)F>>CC(C)(C)NC(=O)CCN(C(=O)c1cc(Cl)cc(OCCNc2ccncc2)c1)C1CCC1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20100267696A1,CCOC(=O)c1csc(C2CCN(C(=O)OC(C)(C)C)CC2)c1>>CC(C)(C)OC(=O)N1CCC(c2cc(C(=O)O)cs2)CC1,,[Na+],[OH-],,,test
US05539112,CCOC(=O)Oc1cc([N+](=O)[O-])c(F)c(F)c1F>>CCOC(=O)Oc1cc(N)c(F)c(F)c1F,[Pd],CCOC(C)=O,,[H][H],,test
US20130143863A1,COC(=O)c1ccc(C#N)cc1CBr.COc1ccc(CN)cc1>>COc1ccc(CN2Cc3cc(C#N)ccc3C2=O)cc1,,C1CCOC1,CCOC(C)=O,,,test
US05821384,CC(=O)O.CC(=O)OC(C)=O>>C=COC(C)=O.CC=O,,CC(=O)O,,,,test
US20090247746A1,COC(=O)c1sccc1S(=O)(=O)N(C)c1cccc2cc(-c3nccs3)[nH]c12>>CN(c1cccc2cc(-c3nccs3)[nH]c12)S(=O)(=O)c1ccsc1C(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20020193402A1,O=S(=O)(c1ccccc1)C1CC2(c3ccccc3)C(OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)CCC1N2Cc1ccccc1>>O=S(=O)(c1ccccc1)C1CC2(c3ccccc3)NC1CCC2OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1,[Pd],CCO,,,,test
US04547516,CCS.COC=C1C(=O)OC(C)(C)OC1=O>>CCSC=C1C(=O)OC(C)(C)OC1=O,,CCO,,,,test
US20140255381A1,CC(C)CO.Nc1cccc(O)c1>>CC(C)COc1cccc(N)c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05216026,NS(=O)(=O)Cc1ccccc1.O=C=Nc1ccc(Cl)cc1>>O=C(Nc1ccc(Cl)cc1)NS(=O)(=O)Cc1ccccc1,,CC(C)=O,,[Na+].[OH-],,test
US04034088,CC(=O)OCC1=C(C(=O)OC(C)(C)C)N2C(=O)C(N)C2SC1.CSc1nccn1CC(=O)O>>CSc1nccn1CC(=O)NC1C(=O)N2C(C(=O)OC(C)(C)C)=C(COC(C)=O)CSC12,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05475013,NC(=O)CC(NC(=O)NCc1ccccc1)C(N)=O.O=C([O-])c1ccc2ccccc2n1>>NC(=O)CC(NC(=O)c1ccc2ccccc2n1)C(N)=O,[Pd],ClCCl,,CCO,,test
US20110263626A1,NCc1ccc(Oc2ccccc2Cl)cc1Cl.O=C(NC1(C(=O)O)CC1)c1cncnc1>>O=C(NC1(C(=O)NCc2ccc(Oc3ccccc3Cl)cc2Cl)CC1)c1cncnc1,,C1CCOC1,CN(C)C=O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US07071201B2,Brc1ccccn1.O=Cc1ccc2c(c1)N(C1CCN(CCc3ccc(F)cc3)CC1)CC2>>OC(c1ccc2c(c1)N(C1CCN(CCc3ccc(F)cc3)CC1)CC2)c1ccccn1,,CCOCC,,,,test
US20100278833A1,Cc1ccccc1C(C)Oc1cc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)sc1C(N)=O>>Cc1ccccc1C(C)Oc1cc(-n2cnc3cnc(CO)cc32)sc1C(N)=O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130217680A1,COC(=O)Cc1cccc(F)c1[N+](=O)[O-]>>COC(=O)Cc1cccc(F)c1N,[Pd],CCOC(C)=O,,,,test
US20120035132A1,CC(C)OB(OC(C)C)OC(C)C.CC(OC1CCCCO1)c1cc(OC2CCCCO2)ccc1Br>>CC1OB(O)c2ccc(O)cc21,,C1CCOC1,,Cl,[Li]CCCC,test
US20110311474A1,COC1CCC(OC)O1.Cc1ccc(S(=O)(=O)n2ccc3c2ncc2nnc([C@@H]4CC[C@H](N)C4)n23)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c2ncc2nnc([C@@H]4CC[C@H](n5cccc5)C4)n23)cc1,,ClCCl,O,Cl,CC(=O)[O-].[Na+],test
US06127414,CC(C)(C)OC(=O)N[C@H](CCCNC(=O)OCc1ccccc1)C(=O)Oc1ccccc1[N+](=O)[O-].N[C@@H](CO)c1ccccc1>>CC(C)(C)OC(=O)N[C@H](CCCNC(=O)OCc1ccccc1)C(=O)N[C@@H](CO)c1ccccc1,,ClCCl,,,,test
US20140249177A1,C[C@H]1CCC[C@@H](C)N1CCNC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(-c4ccnn4C)ccn23)c1.O=C(O)/C=C\C(=O)O>>C[C@H]1CCC[C@@H](C)N1CCNC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(-c4ccnn4C)ccn23)c1.O=C(O)/C=C\C(=O)O,,CCOC(C)=O,,,,test
US20140221393A1,CCCn1ncn(-c2ccc(N3CCN(c4ccc(OC)cc4)CC3)cc2)c1=O>>CCCn1ncn(-c2ccc(N3CCN(c4ccc(O)cc4)CC3)cc2)c1=O,,Br,,,,test
US06479524B1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cc(Br)ccc1C(=O)N1CCCC1>>CCOC(=O)/C=C/c1cc(Br)ccc1C(=O)N1CCCC1,,Cc1ccccc1,,,,test
US20140094462A1,C=CC[C@@H](CC(=O)OC(C)(C)C)C(=O)NC[C@H](O)c1ccccc1.C=CC[C@H](O[Si](C)(C)C(C)(C)C)C(=O)O>>C=CC[C@@H](CC(=O)OC(C)(C)C)C(=O)NC[C@H](OC(=O)[C@H](CC=C)O[Si](C)(C)C(C)(C)C)c1ccccc1,,CCOC(C)=O,ClCCl,,,test
US20090023758A1,COc1ccc(C(N)=O)c([N+](=O)[O-])c1>>COc1ccc(C(N)=O)c(N)c1,[Ni],CCO,,,,test
US20080207891A1,CCCc1nccn1-c1ncnc2nc[nH]c12.Cc1ccc(C(=O)OC[C@H]2O[C@H](Cl)C[C@@H]2OC(=O)c2ccc(C)cc2)cc1>>CCCc1nccn1-c1ncnc2c1ncn2[C@H]1C[C@H](OC(=O)c2ccc(C)cc2)[C@@H](COC(=O)c2ccc(C)cc2)O1,,CC#N,Cc1ccccc1,[Na],,test
US20080287479A1,O=C(O)C1CCC(C(F)(F)F)CC1.O=S(Cl)Cl>>O=C(Cl)C1CCC(C(F)(F)F)CC1,,ClCCl,,,,test
US20150119241A1,CC1c2cccc(N)c2CC12CCCC2.Cn1nc(C(F)F)c(C(=O)Cl)c1Cl>>CC1c2cccc(NC(=O)c3c(C(F)F)nn(C)c3Cl)c2CC12CCCC2,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US04147869,Nc1ccc(O)c2c1NC(=O)CC2.O=C(Cl)C1CCCCC1>>O=C1CCc2c(O)ccc(NC(=O)C3CCCCC3)c2N1,,c1ccncc1,,,,test
US20050277670A1,Cc1cccc(C)c1C(=O)NCCC(C)N1CCC(N(Cc2cccc(C#N)c2)c2ccc(OCC(=O)OC(C)(C)C)cc2)CC1>>Cc1cccc(C)c1C(=O)NCCC(C)N1CCC(N(Cc2cccc(C#N)c2)c2ccc(OCC(=O)O)cc2)CC1,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US20130109854A1,CCN1CC[C@@H](O)C1.Cc1ccc(S(=O)(=O)Cl)cc1>>CCN1CC[C@@H](OS(=O)(=O)c2ccc(C)cc2)C1,,Cc1ccccc1,,CCN(CC)CC,,test
US20110282100A1,CC12CC3CC(C)(C1)CC(Br)(C3)C2.NC=O>>CC12CC3CC(C)(C1)CC(NC=O)(C3)C2,,ClCCl,,,,test
US20130296436A1,Cc1cc([N+](=O)[O-])c(C)cc1OCC(F)(F)CC(C)(C)C>>CCCC(F)(F)COc1cc(C)c(N)cc1C,,CCO,,[H][H],,test
US20130252941A1,N#Cc1cc(Cl)c(/N=C/c2cnccc2N=[N+]=[N-])c(Cl)c1>>N#Cc1cc(Cl)c(-n2cc3cnccc3n2)c(Cl)c1,,Cc1ccccc1,,,,test
US05283335,C1CCOC1.COC(=O)c1ccc(N)c(N)c1C(=O)OC.O=CC=O>>COC(=O)c1ccc2ncccc2c1C(=O)OC,,O,,,,test
US20040132726A1,CCOC(=O)N1CCN(Cc2noc(-c3cccc(I)c3)n2)CC1.OB(O)c1ccoc1>>CCOC(=O)N1CCN(Cc2noc(-c3cccc(-c4ccoc4)c3)n2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20150353473A1,CN1CCNCC1.c1ccc2c(OCC3CO3)cccc2c1>>CN1CCN(CC(O)COc2cccc3ccccc23)CC1,,CCO,,,,test
US20050096380A1,CCOC(=O)/C=C(C)/C=C/C(F)=C(/C)c1cc2c(cc1OCC)OC(C)(C)C=C2CC>>CCOc1cc2c(cc1/C(C)=C(F)\C=C\C(C)=C\C(=O)O)C(CC)=CC(C)(C)O2,,C1CCOC1,CCO,[Na+].[OH-],,test
US20150266890A1,NC1CCCC1.O=C(O)c1cccc(S(=O)(=O)Cl)c1>>O=C(O)c1cccc(S(=O)(=O)NC2CCCC2)c1,,C1CCOC1,O,[Na+].[OH-],,test
US04663347,C=CC(=O)OCC.Cc1coc2cccc(O)c12>>CCOC(=O)/C=C/c1oc2cccc(O)c2c1C,,C1COCCO1,,CC(=O)O,,test
US20130296301A1,O=C1c2ccccc2C(=O)N1CCOCc1ccccc1>>NCCOCc1ccccc1,,CCO,,NN,,test
US20050113400A1,CCOC(C)=O.CO.Cc1ccc2c(c1)C(=O)OC2=O>>COC(=O)c1ccc(C)cc1C(=O)OC,,CO,,O=S(=O)(O)O,,test
US04885397,C1CCCCCC2OC2CCCC1>>O=C1CCCCCCCCCCC1,,CN1CCCC1=O,,[Cl-].[Li+],,test
US04064135,CC(C)(C)NCC(O)COc1ncc(C(=O)NCCC2C3CCC2CC3)s1.Cl>>CC(C)(C)NCC(O)COc1ncc(C(=O)NCCC2C3CCC2CC3)s1.Cl,,CCOCC,,,,test
US20090163469A1,Cc1nccc(-c2sc(N)nc2C)n1.O=C(c1ncc[nH]1)c1ncc[nH]1>>Cc1nccc(-c2sc(NC(=O)n3ccnc3)nc2C)n1,,ClCCl,,CN(C)C=O,,test
US20060094768A1,C=C(C)Br.O=Cc1sc(-c2ccc(C(F)(F)F)cc2)cc1B(O)O>>C=C(C)c1cc(-c2ccc(C(F)(F)F)cc2)sc1C=O,,C1COCCO1,,[Cs+].[F-],,test
US20130085143A1,Cc1cc(C)cc(CC(=O)O)c1.Cc1ccc(CC(N)C(=O)Nc2ccc(-c3cn4c(n3)sc3ccccc34)cc2)cc1>>Cc1ccc(C[C@H](NC(=O)Cc2cc(C)cc(C)c2)C(=O)Nc2ccc(-c3cn4c(n3)sc3ccccc34)cc2)cc1,CN(C)c1ccncc1,ClCCl,,CC(C)N=C=NC(C)C,,test
US20120184553A1,C[Mg]Br.O=Cc1ccc(OCc2ccc(F)c(F)c2)c(C(=O)Nc2cccnc2)c1>>CC(O)c1ccc(OCc2ccc(F)c(F)c2)c(C(=O)Nc2cccnc2)c1,,C1CCOC1,,O=S(=O)(O)O,,test
US20090143439A1,Cc1cc(S(N)(=O)=O)cs1.NC(=O)Nc1cc(Br)cc(N)n1.O=C(Cl)Oc1ccccc1>>Cc1cc(S(=O)(=O)NC(=O)Nc2cc(Br)cc(NC(N)=O)n2)cs1,,CC#N,,CCN(CC)CC,,test
US20160221972A1,COC(=O)c1ccc2c(c1)NC(=O)CN(CCc1ccc(OC)cc1)C2.NO>>COc1ccc(CCN2CC(=O)Nc3cc(C(=O)NO)ccc3C2)cc1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20120101083A1,CCCOc1ccc(-c2nc(-c3ccc4c(c3)CCN(C(=O)OC(C)(C)C)CC4)no2)cc1C#N>>CCCOc1ccc(-c2nc(-c3ccc4c(c3)CCNCC4)no2)cc1C#N,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140213571A1,O=Cc1c(-c2cc(Br)cnc2Cl)nc2ccccn12>>OCc1c(-c2cc(Br)cnc2Cl)nc2ccccn12,,CO,,O,[BH4-].[Na+],test
US04818765,CCCCCCCCO.O=C(O)Cc1cccc(C(F)(F)F)c1>>CCCCCCCCOC(=O)Cc1cccc(C(F)(F)F)c1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20150291557A1,CC(C)(C)C(O)(c1cncnc1)c1ccc(Br)cc1F.CI>>COC(c1cncnc1)(c1ccc(Br)cc1F)C(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US06011028,COC(=O)C=CCC1CCCCC(=O)N1C(=O)OC(C)(C)C.[Li]CC=C>>C=CCC(CC(=O)OC)CC1CCCCC(=O)N1C(=O)OC(C)(C)C,[Cu]I,C1CCOC1,,[Cl-].[NH4+],,test
US20100216794A1,NC(=S)Nc1ccc(Oc2ccccc2)cn1.O=CCCl>>c1ccc(Oc2ccc(Nc3nccs3)nc2)cc1,,CN(C)C=O,,,,test
US05409946,CC(C)(C)OC(=O)N1CCC1C(=O)O.CC(C)COC(=O)Cl.CN1CCOCC1>>Cc1cc([C@@H]2CCN2)on1.Cl,,C1CCOC1,,CO,,test
US20130317064A1,Cc1cc(C(F)(F)F)nn1CC(=O)N1CCC(c2nc(C(=O)O)cs2)CC1.NO>>Cc1cc(C(F)(F)F)nn1CC(=O)N1CCC(c2nc(C(=O)NO)cs2)CC1,,CC#N,,Cl,,test
US20140288063A1,CCOC(=O)c1cnc(SC)nc1Cl.COc1ccc(CO)cc1Cl>>CCOC(=O)c1cnc(SC)nc1OCc1ccc(OC)c(Cl)c1,,CN(C)C=O,,O,[H-].[Na+],test
US04764239,CC(C)(C)N.O=S(=O)(Cl)c1ccc(C2CCCCC2)cc1>>CC(C)(C)NS(=O)(=O)c1ccc(C2CCCCC2)cc1,,C1COCCO1,,,,test
US20110034507A1,COC(=O)c1cccc(C(=O)n2ccc3cc(OC)ccc32)c1>>COC(=O)c1cccc(C(=O)n2ccc3cc(O)ccc32)c1,,ClCCl,,BrB(Br)Br,,test
US20040224970A1,CC(=O)CNc1ccc(Cl)cc1Cl.Cc1ccccc1.O=C1CCN(N2CCCCC2)C(=O)C1>>Cc1cn(-c2ccc(Cl)cc2Cl)c2c1C(=O)N(C1CCCCC1)CC2,,O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20070167501A1,COC(=O)C12CCC(NC(=O)OCc3ccccc3)(CC1)CC2>>O=C(NC12CCC(C(=O)O)(CC1)CC2)OCc1ccccc1,,CCO,,[Na+].[OH-],,test
US20030232848A1,CC(C)(C)c1ccc(S(=O)(=O)Nc2c(-c3ccc4c(c3)OCO4)c(OCCO)nn2Cc2ccccc2)cc1>>CC(C)(C)c1ccc(S(=O)(=O)Nc2[nH]nc(OCCO)c2-c2ccc3c(c2)OCO3)cc1,,CC(=O)O,,[H][H],,test
US20140080798A1,Cc1cc([N+](=O)[O-])ccc1C1=CCN(C(=O)OC(C)(C)C)CC1>>Cc1cc(N)ccc1C1CCN(C(=O)OC(C)(C)C)CC1,[Pd],CN(C)C=O,,,,test
US20020161014A1,Nc1cc([N+](=O)[O-])ccc1C(=O)Nc1ccccc1Cl.O=C(Cl)CCl>>O=c1c2ccc([N+](=O)[O-])cc2nc(CCl)n1-c1ccccc1Cl,,CC(=O)O,,,,test
US20070142454A1,COC(=O)c1cc2ccccc2[nH]1>>O=C(O)c1cc2ccccc2[nH]1,,CO,O,[Na+].[OH-],,test
US20140275080A1,O=[N+]([O-])c1ccc(Oc2ccnc(-c3cncs3)c2)cn1>>Nc1ccc(Oc2ccnc(-c3cncs3)c2)cn1,[Pd],CCOC(C)=O,CO,,,test
US06271225B1,O=C(Nc1ccccc1S)c1c(Br)sc2c1CCCC2>>O=C1Nc2ccccc2Sc2sc3c(c21)CCCC3,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150376208A1,NC(=O)CCC(=O)NCl.Nc1c(O)cccc1[N+](=O)[O-]>>Nc1c(O)cc(Cl)cc1[N+](=O)[O-],,CC#N,,,,test
US20130090347A1,CC(C)(C)C(=O)Cl.Nc1ccc(C#Cc2ccccc2)cn1>>CC(C)(C)C(=O)Nc1ccc(C#Cc2ccccc2)cn1,,ClCCl,,c1ccncc1,,test
US20120208827A1,CNC(=O)c1ccc2nc(-c3ccc(-c4ccccc4)cc3)n(CC3CCN(C(=O)OC(C)(C)C)C3)c2c1>>CNC(=O)c1ccc2nc(-c3ccc(-c4ccccc4)cc3)n(CC3CCNC3)c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040229861A1,Nc1ccncc1NC1CCN(Cc2ccccc2)CC1.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2ccncc2n1C1CCN(Cc2ccccc2)CC1,,C1CCOC1,,,,test
US04762843,C#CC=O.CN(C)C=O.NC1=CC(=O)CCC1>>O=C1CCCc2ncccc21,,CN(C)C=O,,,,test
US20120122992A1,NC1CCC(N)CC1.O=C1NC2CSC(CCCCC(=O)ON3C(=O)CCC3=O)C2N1>>NC1CCC(NC(=O)CCCCC2SCC3NC(=O)NC32)CC1,,CN(C)C=O,,CCOCC,,test
US20140275016A1,CN1CCC(C(=O)Nc2cc(Oc3ccc([N+](=O)[O-])nc3)ccn2)CC1>>CN1CCC(C(=O)Nc2cc(Oc3ccc(N)nc3)ccn2)CC1,[Pd],CCOC(C)=O,CO,,,test
US20150104384A1,C#CCN(Cc1cncnc1)C(=O)OCC>>CCOC(=O)N1Cc2ccncc2C1,,Cc1ccccc1C,,,,test
US20110136780A1,CC[C@@H](NCc1ccnc2c1c(C(=O)OC)cn2C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CC[C@@H](NCc1ccnc2[nH]cc(C(=O)OC)c12)C(=O)O.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20090005436A1,BrCc1ccccc1.CC(C)(C)OC(=O)NNC(=O)Cc1cc(=O)oc2cc(O)ccc12>>CC(C)(C)OC(=O)NNC(=O)Cc1cc(=O)oc2cc(OCc3ccccc3)ccc12,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US06288061B1,CC(C)(C)OC(=O)C(=NO)C(=O)c1ccc(Cl)cc1.NCc1ccc(CCO)cc1>>CC(C)(C)OC(=O)c1nc(-c2ccc(CCO)cc2)[nH]c1-c1ccc(Cl)cc1,,c1ccncc1,,,,test
US20110166163A1,CCC1CC=C(c2c(-c3ccccc3)oc3ncnc(O[C@H](C)CCCCC(=O)O)c23)CC1>>CCC1CCC(c2c(-c3ccccc3)oc3ncnc(O[C@H](C)CCCCC(=O)O)c23)CC1,[Pd],CC(=O)O,,,,test
US20080261979A1,CS(=O)(=O)Cl.Cc1nc(Br)sc1CO>>Cc1nc(Br)sc1COS(C)(=O)=O,,ClCCl,,CCN(CC)CC,O,test
US20150284367A1,COc1nc(Nc2cc(Cl)nnc2C(N)=O)ccc1C(C)C.NCCN>>COc1nc(Nc2cc(NCCN)nnc2C(N)=O)ccc1C(C)C,,CN1CCCC1=O,,[NH4+].[OH-],,test
US20150232435A1,C(=Cc1ccccc1)CN1CCNCC1.CC(C)(C)c1nc(N2CCN(CCCCN)CC2)cc(C(F)(F)F)n1.O=C(n1ccnc1)n1ccnc1>>CC(C)(C)c1nc(N2CCN(CCCCNC(=O)N3CCN(CC=Cc4ccccc4)CC3)CC2)cc(C(F)(F)F)n1,,CO,ClC(Cl)Cl,,,test
US20070191340A1,CN=C=O.FC(F)(F)c1ccccc1-c1ccc(CN2CCNC(Cc3ccccc3)C2)cc1>>CNC(=O)N1CCN(Cc2ccc(-c3ccccc3C(F)(F)F)cc2)CC1Cc1ccccc1,,ClCCl,,,,test
US20160016948A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.Cc1nc2cnc(N(C(=O)OC(C)(C)C)c3ccnc(Cl)n3)cc2n1C(C)C>>Cc1nc2cnc(N(C(=O)OC(C)(C)C)c3ccnc(-c4cn[nH]c4)n3)cc2n1C(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20140296136A1,O=C1CCC(=O)N1Br.Oc1cc(O)c2ccccc2n1>>O=c1[nH]c2ccccc2c(O)c1Br,,ClCCl,,,,test
US20090137499A1,CC(=O)OCc1ccc(Cc2ccc(F)cc2)c(O[C@@H]2O[C@H]([C@@H](C)OC(=O)c3ccccc3)[C@@H](OC(=O)c3ccccc3)[C@H](OC(=O)c3ccccc3)[C@H]2OC(=O)c2ccccc2)c1>>C[C@@H](O)[C@H]1O[C@@H](Oc2cc(CO)ccc2Cc2ccc(F)cc2)[C@H](O)[C@@H](O)[C@@H]1O,,C1CCOC1,CO,O=C([O-])[O-].[K+].[K+],,test
US20030153596A1,Cn1cccc1C=O.O=[N+]([O-])O>>Cn1cc([N+](=O)[O-])cc1C=O,,CC(=O)O,,[Na+].[OH-],,test
US20100113782A1,Cc1ccc(NC(=O)c2ccc(Cl)nc2)cc1I.OC1(c2ccccc2)CCNCC1>>Cc1ccc(NC(=O)c2ccc(N3CCC(O)(c4ccccc4)CC3)nc2)cc1I,CN(C)c1ccncc1,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US06245770B1,CCCN=C=S.Nc1cc2ccccc2cc1C(=O)O>>CCCn1c(=S)[nH]c2cc3ccccc3cc2c1=O,,CC(C)O,,CCN(CC)CC,,test
US20130261101A1,CC(=O)c1cc(Cl)c(C)c2c1OCCN=C2>>Cc1c(Cl)cc(C(C)O)c2c1CNCCO2,,CO,,[BH4-].[Na+],,test
US20110124668A1,CC(=O)O.NC(=O)Nc1[nH]c2cc(Oc3ccc(N)cc3)ccc2c1C(N)=O>>CC(=O)Nc1ccc(Oc2ccc3c(C(N)=O)c(NC(N)=O)[nH]c3c2)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130338066A1,CC(C)(C)[Si](C)(C)Cl.N[C@@H](CCO)c1ccccc1>>CC(C)(C)[Si](C)(C)OCC[C@H](N)c1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
US20090170841A1,CCc1cccc(C)c1CBr.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CCc1cccc(C)c1C[PH3+].[Br-],,Cc1ccccc1,,,,test
US05250540,C=CCC(Cl)c1cccnc1OC>>C=CCCc1cccnc1OC,[Zn],CO,,,,test
US20120122846A1,NC[C@@H]1CCN(Cc2ccccc2)C[C@H]1O.O=C(n1ccnc1)n1ccnc1>>O=C1NC[C@@H]2CCN(Cc3ccccc3)C[C@H]2O1,,CCOC(C)=O,,CN(C)C=O,,test
US20020165241A1,CCc1cnc(Cl)nc1.NCC1CCN(C(=O)[C@@H]2C[C@H]2c2ccccc2)CC1>>CCc1cnc(NCC2CCN(C(=O)[C@@H]3C[C@H]3c3ccccc3)CC2)nc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090156600A1,COC(=O)COc1ccc(Cl)c2nc(OC(C)C)c(Cc3ccc(F)cc3)c(C)c12>>Cc1c(Cc2ccc(F)cc2)c(OC(C)C)nc2c(Cl)ccc(OCC(=O)O)c12,,O=CO,,CO,[Na+].[OH-],test
US20160068532A1,COC(=O)c1cc2cn[nH]c2cc1Cl.O=C1CCC(=O)N1I>>COC(=O)c1cc2c(I)n[nH]c2cc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20040157891A1,COc1ccc(-c2nc(OC)oc2-c2ccc(OCCN)cc2)cc1.C[Si](C)(C)N=C=O>>COc1ccc(-c2nc(OC)oc2-c2ccc(OCCNC(N)=O)cc2)cc1,,ClCCl,,CCN(CC)CC,,test
US20080171403A1,CCOC(=O)c1[nH]cc(CC)c1CC>>CCc1c[nH]cc1CC,,OCCO,,[K+].[OH-],,test
US06740662B1,CCOC(=O)CBr.CCn1c(=O)c(C2CCNCC2)c(-c2cccc(Br)c2)c2ccc(C)nc21>>CCOC(=O)CN1CCC(c2c(-c3cccc(Br)c3)c3ccc(C)nc3n(CC)c2=O)CC1,,CCOC(C)=O,,CC#N,CCN(CC)CC,test
US20110144105A1,CC(C)(C)[Si](OCCOc1cnc2c(c1)cc(C(=CC1CCCC1)c1ccc(S(C)(=O)=O)cc1)n2S(=O)(=O)c1ccccc1)(c1ccccc1)c1ccccc1>>CS(=O)(=O)c1ccc(C(=CC2CCCC2)c2cc3cc(OCCO)cnc3[nH]2)cc1,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04619787,CC(C)(C)[Si](C)(C)Cl.CC1(C)OC[C@@H]([C@@H]2CC(=O)N2)O1>>CC1(C)OC[C@@H]([C@@H]2CC(=O)N2[Si](C)(C)C(C)(C)C)O1,,CCOCC,CN(C)C=O,CCN(CC)CC,,test
US20060084699A1,CN.Cc1c(Cl)ccc(S(=O)(=O)Cl)c1Cl>>CNS(=O)(=O)c1ccc(Cl)c(C)c1Cl,,ClCCl,,CCN(CC)CC,Cl,test
US20130252952A1,CC(=O)c1cc(Br)ccc1F.C[Si](C)(C)C#N.N>>CC(N)(C#N)c1cc(Br)ccc1F,,N,,[Cl-].[NH4+],,test
US20030100779A1,CC(CCc1ccc(C(=O)c2cc(C(=O)O)c(C(=O)c3ccc(CCC(C)CC(C)(C)C)cc3)cc2C(=O)O)cc1)CC(C)(C)C>>CC(CCc1ccc(Cc2cc(C(=O)O)c(Cc3ccc(CCC(C)CC(C)(C)C)cc3)cc2C(=O)O)cc1)CC(C)(C)C,[Pd],C1CCOC1,,[H][H],,test
US20120108592A1,CC(=O)Cl.O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1cc(Cl)ccc1O>>CC(=O)Oc1ccc(Cl)cc1C(=O)Nc1ccc([N+](=O)[O-])cc1Cl,,C1CCOC1,,ClCCl,c1ccncc1,test
US20110144105A1,CCC(O)(CC)c1ccc(C(=CC2CCCC2)c2cc3cccnc3[nH]2)cc1>>CCC(O)(CC)c1ccc(C(CC2CCCC2)c2cc3cccnc3[nH]2)cc1,[Pd],CO,,,,test
US20090275537A1,NNC(=O)c1nc2ccccc2s1.O=N[O-]>>[N-]=[N+]=NC(=O)c1nc2ccccc2s1,,O,,Cl,,test
US20110201643A1,CN(C)CCCC(=O)N1CCc2cc(C(=O)NOC3CCCCO3)ccc2C1.Cl>>CN(C)CCCC(=O)N1CCc2cc(C(=O)NO)ccc2C1.Cl,,CO,,,,test
US20050065210A1,CN(C)CCN(C)C(=O)CO[C@@H]1CC[C@@H](N(C)C(=O)OCc2ccccc2)CC1>>CN[C@@H]1CC[C@@H](OCC(=O)N(C)CCN(C)C)CC1,[Pd],CCOC(C)=O,,,,test
US20050131052A1,CC(=O)OCC(=O)N(CC(=O)OC(C)(C)C)[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1>>CC(=O)OCC(=O)N(CC(=O)O)[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1,,ClCCl,,O=C(O)C(F)(F)F,,test
US09006451B1,COc1ccc(C(C)=O)cc1OC.O=Cc1cccnc1Nc1ccccc1>>COc1ccc(C(=O)C=Cc2cccnc2Nc2ccccc2)cc1OC,,CO,,Cl,,test
US20060183762A1,CC(C)(C)OC(=O)N[C@H]1CCN(c2c(F)c(F)c(C(=O)OCc3ccccc3)c(F)c2F)C1.NC1CC1>>CC(C)(C)OC(=O)N[C@H]1CCN(c2c(F)c(F)c(C(=O)OCc3ccccc3)c(NC3CC3)c2F)C1,,CS(C)=O,,,,test
US20160272595A1,CCS(=O)(=O)c1ccc(Cl)cc1Cn1cnc2c(Cl)c(CN3CCC[C@H](N)C3)c(C(F)(F)F)cc2c1=O.OCCBr>>CCS(=O)(=O)c1ccc(Cl)cc1Cn1cnc2c(Cl)c(CN3CCC[C@H](NCCO)C3)c(C(F)(F)F)cc2c1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US06884801B1,CN(C)C=CC(=O)c1ccccc1[N+](=O)[O-].N=C(N)N>>Nc1nccc(-c2ccccc2[N+](=O)[O-])n1,,CCO,,Cl,[Na+].[OH-],test
US20060079533A1,Br.CC(C)(C)C1C(O)C(c2ccc(O)cc2)C(CO)CN1Cc1ccccc1>>Br.OCC1CNCC(O)C1c1ccc(O)cc1,[Pd],CO,,,,test
US20140221340A1,CC(C)(C)OC(=O)N1CC2(C1)CN(c1ccc(F)cc1)C2>>Fc1ccc(N2CC3(CNC3)C2)cc1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20050026989A1,COC(=O)c1cn(-c2cnc3ccccc3c2)c2ccccc12>>O=C(O)c1cn(-c2cnc3ccccc3c2)c2ccccc12,,C1CCOC1,O,[Li+].[OH-],,test
US04311694,CCCCCCCCCCCCCCCCNc1ccc(C(=O)[O-])cc1.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.[Na+]>>CCCCCCCCCCCCCCCCNc1ccc(C(=O)[O-])cc1.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.[Na+],,O,,,,test
US20070287726A1,CCc1cccc(C)c1CNc1cc(C(=O)N(C)C)nc2c(CO)c(C)[nH]c12>>CCc1cccc(C)c1CNc1cc(C(=O)N(C)C)nc2c(C)c(C)[nH]c12,[Pd],CC(=O)O,,[H][H],,test
US20070155839A1,CC(C)(C)OC(=O)n1cccc1B(O)O.CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(Br)cc2)CC(C)(C)C1>>CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(-c3cccn3C(=O)OC(C)(C)C)cc2)CC(C)(C)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20160145247A1,CS(=O)(=O)Cl.OCc1cccc(Br)c1Cl>>CS(=O)(=O)OCc1cccc(Br)c1Cl,,ClCCl,,,,test
US06187777B1,CC1CC(c2ncc3nc(-c4cc5ccccc5o4)cc-3[nH]2)CCN1.CO.Cl>>CC1CC(c2ncc3nc(-c4cc5ccccc5o4)cc-3[nH]2)CCN1.Cl.O,,CO,,CCOC(C)=O,,test
US06468979B1,OCc1csc(-n2cncn2)n1>>O=Cc1csc(-n2cncn2)n1,O=[Mn]=O,CO,ClC(Cl)Cl,,,test
US20100305096A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Cn1cnc2c(N3CCOCC3)nc(Cl)nc21>>Cn1c(C2(O)CCN(C(=O)OC(C)(C)C)CC2)nc2c(N3CCOCC3)nc(Cl)nc21,,C1CCOC1,,CN(C)CCN(C)C,[Li]CCCC,test
US04315009,CN=C=S.N=C(N)Nc1nc(-c2cccc(N)c2)co1>>CNC(=S)Nc1cccc(-c2coc(NC(=N)N)n2)c1,,CN(C)C=O,,,,test
US20120302756A1,CC(C)(C)[S@](=O)/N=C(\CCCCl)C1CCCCC1>>CC(C)(C)[S@](=O)N1CCC[C@@H]1C1CCCCC1,,CO,,,,test
US20140135330A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.COc1ccc([C@@H]2OC(=O)N[C@H]2CO)cc1>>COc1ccc([C@@H]2OC(=O)N[C@H]2CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1,,CN(C)C=O,,c1c[nH]cn1,,test
US20030158197A1,Cc1cc(C)c(-c2cccn3c2cc2nc(C)cc(Cl)c23)c(C)c1.NCCN>>Cc1cc(C)c(-c2cccn3c2cc2nc(C)cc(NCCN)c23)c(C)c1,,CN1CCCC1=O,,,,test
US20160095844A1,CCOC(=O)c1nnc(-c2ccc3c(c2)NC(=O)C3(C)C)o1>>CC1(C)C(=O)Nc2cc(-c3nnc(CO)o3)ccc21,,C1CCOC1,,[BH4-].[Li+],,test
US20160264567A1,O=C(OCc1ccccc1)N1CC(OC(F)(F)F)C1>>FC(F)(F)OC1CNC1,[Pd],CO,,Cl,,test
US20070191364A1,CCN(CC)C(=O)N(C1CCCCCC1)C1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)N[C@H]2CC[C@@H](NC(=O)OC(C)(C)C)CC2)CC1>>CCN(CC)C(=O)N(C1CCCCCC1)C1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)N[C@@H]2CC[C@H](N)CC2)CC1,,C1COCCO1,Cl,,,test
US20060217417A1,CN(C)C=O.O=C(O)c1cnc(Cl)cc1Cl>>NC(=O)c1cnc(Cl)cc1Cl,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20150315198A1,COc1ccc(CNc2ncnc3nn(Cc4ccc(Cn5cccn5)cc4)cc23)c(OCC2(C(C)(C)C)OCCO2)c1>>COc1ccc(CNc2ncnc3nn(Cc4ccc(Cn5cccn5)cc4)cc23)c(OCC(=O)C(C)(C)C)c1,,C1CCOC1,Cl,,,test
US20100068197A1,COC(=O)Cl.COc1ccc(N(C)c2nc(NCCN)nc3ccc(C)cc23)cc1>>COC(=O)NCCNc1nc(N(C)c2ccc(OC)cc2)c2cc(C)ccc2n1,,C1CCOC1,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20120212125A1,CC(=O)CCl.Cc1ccccc1N.S=C=S>>Cc1ccccc1-n1c(C)csc1=S,,CS(C)=O,O,[Na+].[OH-],,test
US20080121870A1,C1CCOC1.CN1CCN(C)C(=O)C1=O.Cc1cccc([Mg]Cl)c1>>Cc1cccc(C(=O)C(=O)c2cccc(C)c2)c1,,C1CCOC1,,,,test
US06028080,COC(=O)c1ccc(Cl)c(-c2cccc(C(c3ccccc3)N(C)C)c2)c1NC(C)=O.Cl>>Cl.O=c1cc(O)c2ccccc2[nH]1,,C1CCOC1,,CCO,,test
US20100029737A1,COC(=O)c1cc2c([nH]1)C(Cc1cccc(OC)c1)CC2>>COc1cccc(CC2CCc3cc(C(=O)O)[nH]c32)c1,,C1CCOC1,,CO,[Li+].[OH-],test
US20090221583A1,NS(=O)(=O)O.O=Cc1ccc(Sc2ccccc2)cc1.[O-][Cl+][O-]>>O=C(O)c1ccc(S(=O)c2ccccc2)cc1,,CC(C)=O,,O,,test
US20080045532A1,CI.O=C(Nc1ccc(-n2nc(C(F)(F)F)c3c2CCCC3)cc1)N1CCCC1>>CN(C(=O)N1CCCC1)c1ccc(-n2nc(C(F)(F)F)c3c2CCCC3)cc1,,CN(C)C=O,,[H-].[Na+],,test
US05910498,CCOC(=O)c1cn(-c2c(F)cc(F)cc2F)c2c(Cl)c(F)c(F)cc2c1=O>>O=C(O)c1cn(-c2c(F)cc(F)cc2F)c2c(Cl)c(F)c(F)cc2c1=O,,CC(=O)O,,Cl,,test
US20110319380A1,C#CCCN1CCCCC1.O=C(OO)c1cccc(Cl)c1>>O=C1CCN2CCCCC2C1,,ClCCl,,,,test
US20020045654A1,CSc1ccc([N+](=O)[O-])cc1CO.O=C(OO)c1cccc(Cl)c1>>CS(=O)(=O)c1ccc([N+](=O)[O-])cc1CO,,CO,ClCCl,O=S([O-])[O-].[Na+].[Na+],,test
US03962281,BrCc1ccc(Br)cc1.CSCS(C)=O>>CSC(Cc1ccc(Br)cc1)S(C)=O,,ClCCl,,C1CCOC1,[H-].[Na+],test
US04537619,O=[N+]([O-])c1ccccc1OC(F)(F)C(F)(F)F>>Nc1ccccc1OC(F)(F)C(F)(F)F,[Ni],C1COCCO1,,[H][H],,test
US20100210655A1,CNc1nc(N2CCN(C)CC2)nc(N2Cc3ccc(C(=O)OC)cc3C2)n1>>CNc1nc(N2CCN(C)CC2)nc(N2Cc3ccc(C(=O)O)cc3C2)n1,,CO,,[Na+].[OH-],,test
US05233035,CC(C)(C)OC(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CO)CS[C@H]12.COc1ccc(O)cc1>>COc1ccc(OCC2=C(C(=O)OC(c3ccccc3)c3ccccc3)N3C(=O)C(NC(=O)OC(C)(C)C)[C@H]3SC2)cc1,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05807859,COC1CCC(OC)O1.NC1c2ccccc2-c2[nH]c(=O)c3nccn3c21>>O=c1[nH]c2c(n3ccnc13)C(n1cccc1)c1ccccc1-2,,CC(=O)O,CO,Cl,CC(=O)[O-].[Na+],test
US20160060257A1,CC(C)(C)OC(=O)NCCO.Oc1ccc(F)cc1Br>>CC(C)(C)OC(=O)NCCOc1ccc(F)cc1Br,,CCOCC,Cc1ccccc1,CCCCP(=CC#N)(CCCC)CCCC,,test
US20110288065A1,CC(C)[Si](C(C)C)(C(C)C)n1ccc(-c2cc(Nc3cnccn3)nc(N[C@@H](C)c3ccc(F)cc3)n2)c1>>C[C@H](Nc1nc(Nc2cnccn2)cc(-c2cc[nH]c2)n1)c1ccc(F)cc1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20130184263A1,CC(C)C1=C2[C@H]3CC[C@H]4[C@@](C)(CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)CC(=O)O)CC[C@@]54C)[C@]3(C)CC[C@@]2(C(=O)CN(Cc2ccc(Cl)cc2)C(=O)OC(C)(C)C)CC1=O>>CC(C)C1=C2[C@H]3CC[C@H]4[C@@](C)(CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)CC(=O)O)CC[C@@]54C)[C@]3(C)CC[C@@]2(C(=O)CNCc2ccc(Cl)cc2)CC1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120258952A1,CCc1nn(Cc2ccccc2)c2cccc(N)c12.COCCOc1ccn2c(C(=O)O)cnc2c1>>CCc1nn(Cc2ccccc2)c2cccc(NC(=O)c3cnc4cc(OCCOC)ccn34)c12,,CN(C)C=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20080262042A1,CN(Cc1cn(S(=O)(=O)c2ccc(C=O)o2)c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C.C[Mg]Br>>CC(O)c1ccc(S(=O)(=O)n2cc(CN(C)C(=O)OC(C)(C)C)c(F)c2-c2cccnc2F)o1,,C1CCOC1,,Cl,,test
US20110152334A1,CCOC(=O)[C@H]1[C@H]2[C@@H]1[C@](NC(=O)CNC(=O)OC(C)(C)C)(C(=O)OCC)C[C@H]2Sc1nnc[nH]1>>CC(C)(C)OC(=O)NCC(=O)N[C@@]1(C(=O)O)C[C@@H](Sc2nnc[nH]2)[C@@H]2[C@H]1[C@H]2C(=O)O,,C1CCOC1,O,[Na+].[OH-],,test
US20140275071A1,Cn1c(=O)n(CCCOC2CCCCO2)c(=O)c2c1nc(OC1CCCC1)n2Cc1ccc(Cl)cc1>>Cn1c(=O)n(CCCOC2CCCCO2)c(=O)c2[nH]c(OC3CCCC3)nc21,[Pd],CO,,O=C[O-].[NH4+],,test
US20140155596A1,COC(=O)c1ccccc1SCC(O)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1>>COC(=O)c1ccccc1SCC(=O)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20070032494A1,COC(=O)c1cc(Cl)c(Cc2cc(C(C)C)c(=O)[nH]n2)c(Cl)c1>>CC(C)c1cc(Cc2c(Cl)cc(CO)cc2Cl)n[nH]c1=O,,C1CCOC1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20080004271A1,CCOC(=O)CC#N.N=C(N)CC1CC1.O=Cc1ccc(Cl)c(Cl)c1>>N#Cc1c(O)nc(CC2CC2)nc1-c1ccc(Cl)c(Cl)c1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20130150326A1,CC(=O)CSc1cccc(CC(=O)O)c1.NNc1ccccc1>>Cc1[nH]c2ccccc2c1Sc1cccc(CC(=O)O)c1,,CC(C)(C)O,,Cl,,test
US20080269196A1,CC(C)N(C)Cc1ccc(CN)cc1.O=C(N1CCc2ccc(Cl)c(OS(=O)(=O)C(F)(F)F)c2CC1)C(F)(F)F>>CC(C)N(C)Cc1ccc(CNc2c(Cl)ccc3c2CCN(C(=O)C(F)(F)F)CC3)cc1,,Cc1ccccc1,,,,test
US05539112,CCCCCCNc1c(F)cc(F)c2oc(-c3ccc(N(CCCN4C(=O)c5ccccc5C4=O)C(C)=O)c(F)c3)cc(=O)c12>>CCCCCCNc1c(F)cc(F)c2oc(-c3ccc(NCCCN4C(=O)c5ccccc5C4=O)c(F)c3)cc(=O)c12,,CCO,,Cl,[Na+].[OH-],test
US05585376,CN(C)C(OC(C)(C)C)OC(C)(C)C.O=C(O)c1cccc([N+](=O)[O-])c1>>CC(C)(C)OC(=O)c1cccc([N+](=O)[O-])c1,,CCOC(C)=O,Cc1ccccc1,,,test
US06002008,CCNCC.N#Cc1cnc2ccc(NC(=O)C=CCBr)cc2c1Nc1cccc(Br)c1>>CCN(CC)CC=CC(=O)Nc1ccc2ncc(C#N)c(Nc3cccc(Br)c3)c2c1,,C1CCOC1,CN(C)C=O,CCOC(C)=O,O,test
US20070259854A1,CCOC(=O)C(C)(C)Br.Nc1ccccc1>>CCOC(=O)C(C)(C)Nc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090291917A1,CC(C)(C)[Si](C)(C)Cl.CN(CCO)c1ccc(C#N)c(Oc2ccc(Br)c(C=O)c2)n1>>CN(CCO[Si](C)(C)C(C)(C)C)c1nc(Oc2ccc(Br)c(C=O)c2)ccc1C#N,,C1CCOC1,,CCN(CC)CC,,test
US05356966,Cc1ccc(O)cc1.O=C(O)COc1ccc(C(O)C(=O)O)cc1>>Cc1ccc2c(c1)C(c1ccc(OCC(=O)O)cc1)C(=O)O2,,O,,,,test
US20120071479A1,CC(C)(C)OC(=O)C1(CNS(=O)(=O)c2cccc(C(=O)O)c2)CCC1.Nc1nc(N)c(C(=O)/N=C2\NCC3(CCNCC3)N2)nc1Cl>>CC(C)(C)OC(=O)C1(CNS(=O)(=O)c2cccc(C(=O)N3CCC4(CC3)CN/C(=N\C(=O)c3nc(Cl)c(N)nc3N)N4)c2)CCC1,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150210688A1,CC(C)(C)OC(=O)N1CCC(c2ccc(C#C[Si](C)(C)C)cc2)CC1>>C#Cc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2)cc1,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090143581A1,CC1(C)C=CC(=O)CC1.CI>>CC1CC(C)(C)C=CC1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20060148790A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.NCCc1ccccc1[N+](=O)[O-]>>CC(C)(C)OC(=O)N1CCC(NCCc2ccccc2[N+](=O)[O-])CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20140045825A1,CNCCN(C)c1nc2c(C)cccc2cc1CNc1ncnc2[nH]cnc12.O=C(O)Cn1ccnn1>>CNC(=O)C(CC(NC)c1nc2c(C)cccc2cc1CNc1ncnc2[nH]cnc12)n1ccnn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160214993A1,CC(C)(C)OC(=O)C1CNC1.CCCCCCCOc1ccc(-c2cnc(-c3ccc(C[C@H](NC(=O)OCc4ccccc4)C(=O)O)cc3)nc2)cc1>>CCCCCCCOc1ccc(-c2cnc(-c3ccc(C[C@H](NC(=O)OCc4ccccc4)C(=O)N4CC(C(=O)OC(C)(C)C)C4)cc3)nc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040082615A1,Nc1cccc(C(F)(F)F)c1.O=C1C(=O)N(c2ccccc2)c2cc(O)ccc21>>O=C1C(=Nc2cccc(C(F)(F)F)c2)c2ccc(O)cc2N1c1ccccc1,CC(=O)O,ClCCl,,,,test
US20090324581A1,CC(C)Cc1ccc(COc2ccc3c(c2)CCN3C(=O)CN(CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc1OC(F)(F)F.O=C(O)C(F)(F)F>>CC(C)Cc1ccc(COc2ccc3c(c2)CCN3C(=O)CNCCC(=O)O)cc1OC(F)(F)F.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20150266895A1,Cc1nc(Cl)cc2c1c(I)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1.O=[Se]=O>>O=Cc1nc(Cl)cc2c1c(I)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1,,C1COCCO1,,,,test
US20070197512A1,CCOC(=O)/C=C/C(=O)N1CC(c2ccccc2)Oc2c(C)cccc21>>Cc1cccc2c1OC(c1ccccc1)CN2C(=O)/C=C/C(=O)O,,CO,,[Na+].[OH-],,test
US20120295884A1,CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(O)ccc12.ClCc1nnn[nH]1>>CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCc3nnn[nH]3)ccc12,,CS(C)=O,O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20110039843A1,CC(C)N.Fc1cnccc1-c1nc2cc(C(F)(F)F)ccc2o1>>CC(C)Nc1cnccc1-c1nc2cc(C(F)(F)F)ccc2o1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05037853,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=CCCc1ccccc1>>CCOC(=O)/C=C/CCc1ccccc1,,Cc1ccccc1,,,,test
US20060194778A1,COC(=O)c1ccc(CNC2CCN(C)CC2)cc1.O=C(Cl)Cc1ccccc1>>COC(=O)c1ccc(CN(C(=O)Cc2ccccc2)C2CCN(C)CC2)cc1,,CO,ClCCl,,,test
US20050090490A1,O=C(Cl)OCCl.O=C(c1ccccc1)C1CN(Cc2ccccc2)CCO1>>Cl.O=C(c1ccccc1)C1CNCCO1,,ClCCCl,,,,test
US20030100770A1,CCN(CCC(=O)N1CCC[C@@H]1C(=O)OC(C)(C)C)CCC(=O)N1CCC[C@@H]1C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CCN(CCC(=O)N1CCC[C@@H]1C(=O)O)CCC(=O)N1CCC[C@@H]1C(=O)O.O=C(O)C(F)(F)F,,ClCCl,O,,,test
US05139564,O=C(O)CCl.Oc1c(Cl)cc(Cl)cc1Cl>>O=C(O)COc1c(Cl)cc(Cl)cc1Cl,,O,,Cl,[Na+].[OH-],test
US04330291,CC(=O)Nc1ccc(Cl)c(O)c1.O=[N+]([O-])O>>CC(=O)Nc1ccc(Cl)c(O)c1[N+](=O)[O-],,O=S(=O)(O)O,,O=P(O)(O)O,,test
US20100029643A1,CCNc1cc(C2CC2)ncc1NC(=O)C(C)NC(=O)OC(C)(C)C>>CCn1c(C(C)N)nc2cnc(C3CC3)cc21,,C1COCCO1,,Cl,,test
US20140057893A1,CC(C)OC(=O)Cl.OCC[C@@H]1C[C@@H]1C1CCNCC1>>CC(C)OC(=O)N1CCC([C@H]2C[C@H]2CCO)CC1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06660744B1,CCOC(=O)CBr.Nc1ncnc2[nH]nc(I)c12>>CCOC(=O)Cn1nc(I)c2c(N)ncnc21,,CN(C)C=O,,[H-].[Na+],,test
US20100261679A1,CNC(=O)c1cc(Oc2ccc3nc(SC)ncc3c2)ccn1.O=C(OO)c1cccc(Cl)c1>>CNC(=O)c1cc(Oc2ccc3nc(S(C)=O)ncc3c2)ccn1,,ClCCl,,,,test
US20030176454A1,Cc1ncccc1Oc1ccc(N)cn1.Clc1nccc2c(-c3ccsc3)cccc12>>Cc1ncccc1Oc1ccc(Nc2nccc3c(-c4ccsc4)cccc23)cn1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20110130361A1,COC(=O)[C@@H]1C[Si](C)(C)CN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1C[Si](C)(C)C[C@H]1CO,,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US06514968B1,BrCCOc1cccc2c1c1ccccc1n2Cc1ccccc1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(CCOc2cccc3c2c2ccccc2n3Cc2ccccc2)CC1,,CC#N,,CCN(CC)CC,,test
US04451463,COC(=O)CCCC(=O)CCl.N=C(NCC(F)(F)F)NC(N)=S>>COC(=O)CCCc1csc(NC(N)=NCC(F)(F)F)n1,,CCO,,,,test
US20150368202A1,O=c1cc(-c2ccccc2)cc(-c2ccccc2)n1O.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>On1c(-c2ccccc2)cc(-c2ccccc2)cc1=S,,Cc1ccccc1,,,,test
US20140206663A1,CC1(OS(C)(=O)=O)CN(C(c2ccccc2)c2ccccc2)C1.C[C@@H]1C(=O)NN=C2COc3ccc(N)cc3N21>>C[C@@H]1C(=O)NN=C2COc3ccc(NC4(C)CN(C(c5ccccc5)c5ccccc5)C4)cc3N21,,CC(C)O,,O=C([O-])[O-].[K+].[K+],,test
US20030232883A1,CCOP(OCC)OCC.O=[N+]([O-])c1ccc(CBr)cc1>>CCOP(=O)(Cc1ccc([N+](=O)[O-])cc1)OCC,,CN(C)C=O,O,,,test
US20070105904A1,C#Cc1cccnc1N.ON=C(Cl)Cc1ccc(OCc2ccc(F)cc2)nc1>>Nc1ncccc1-c1cc(Cc2ccc(OCc3ccc(F)cc3)nc2)no1,,O,,C1CCOC1,CCN(CC)CC,test
US20120165310A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CC12CCC(COc3cccc(Br)c3)(CC1)O2>>CC12CCC(COc3cccc(B4OC(C)(C)C(C)(C)O4)c3)(CC1)O2,,CN(C)C=O,,CC(=O)[O-].[K+],,test
US20160060273A1,CCOC(=O)C1(C)CCN(C2=NOC3(C2)CN(Cc2cc(CC)c(-c4ccc(F)cc4)c(OCC)c2)C3)CC1>>CCOc1cc(CN2CC3(CC(N4CCC(C)(C(=O)O)CC4)=NO3)C2)cc(CC)c1-c1ccc(F)cc1,,CCO,,Cl,[Na+].[OH-],test
US20160272596A1,CC(=O)c1ccc(C(=O)N2C[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)N(Cc3c(OCC(F)(F)F)ccc4ccccc34)c3ccccc32)cc1.Cl>>CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(C)=O)cc2)c2ccccc2N(Cc2c(OCC(F)(F)F)ccc3ccccc23)C1=O.Cl,,C1COCCO1,,,,test
US20080051399A1,O=P(Cl)(Cl)Cl.Oc1ncnc2c1CCC2>>Clc1ncnc2c1CCC2,,ClCCCl,,CCN(C(C)C)C(C)C,,test
US20090137609A1,CCC(O)(C#Cc1ccc(C(CC)(CC)c2ccc(O)c(C)c2)cc1C)CC>>CCC(O)(C=Cc1ccc(C(CC)(CC)c2ccc(O)c(C)c2)cc1C)CC,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US05798354,COC(=O)c1ccc(C#Cc2ccc(OC)c(C34CC5CC(CC(C5)C3)C4)c2)cc1>>COc1ccc(C#Cc2ccc(C(=O)O)cc2)cc1C12CC3CC(CC(C3)C1)C2,,[Na+],[OH-],,,test
US20010047038A1,Cc1ccc(N)c(N)c1.S=C=S>>Cc1ccc2nc(S)[nH]c2c1,,CCO,,[Na+].[OH-],,test
US20110039847A1,CCCc1nnc(-c2ccccc2NC(=O)c2cc(Cl)nc(-c3ccccc3)n2)s1.CN(C)CCN>>CCCc1nnc(-c2ccccc2NC(=O)c2cc(NCCN(C)C)nc(-c3ccccc3)n2)s1,,C1CCOC1,O,,,test
US20060069128A1,C[C@@H](N)[C@@H](O)CN1CCC[C@@H](Cc2ccc(F)cc2)C1.Cn1nnnc1-c1cccc(NC(=O)Oc2ccccc2)c1>>C[C@@H](NC(=O)Nc1cccc(-c2nnnn2C)c1)[C@@H](O)CN1CCC[C@@H](Cc2ccc(F)cc2)C1,,CC#N,,,,test
US20060025459A1,CCOC(=O)c1cc(Br)c(N)c([N+](=O)[O-])c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1cc(Br)c(NC(=O)C(F)(F)F)c([N+](=O)[O-])c1,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20090029981A1,CNC.COCCCOc1ccc([C@H]2[C@H](OCCC=O)CN(C(=O)OCc3ccccc3)C[C@@H]2OCc2ccc3c(c2)N(CCCOC)CCO3)cc1>>COCCCOc1ccc([C@H]2[C@H](OCCCN(C)C)CN(C(=O)OCc3ccccc3)C[C@@H]2OCc2ccc3c(c2)N(CCCOC)CCO3)cc1,,CC(=O)O,CCOC(C)=O,O=C([O-])O.[Na+],,test
US20070032517A1,CC(=O)OC(C)=O.Cn1c(=O)cc(N)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc21>>CC(=O)Nc1cc(=O)n(C)c2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc12,CN(C)c1ccncc1,c1ccncc1,,,,test
US05565577,CCCCC(=N)OC.NCc1ccc(C(=O)O)cc1>>CCCCC(=N)NCc1ccc(C(=O)O)cc1,,CCN(CC)CC,,CN(C)C=O,Cl,test
US20050250810A1,CC(=O)OC(C)=O.CC1=C(CN(C)C(=O)/C=C/c2ccc(N)nc2)Cc2ccccc21>>CC(=O)Nc1ccc(/C=C/C(=O)N(C)CC2=C(C)c3ccccc3C2)cn1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US06500846B1,O=c1c(O)c(-c2ccc3c(c2)OCO3)oc2ccc(Cl)cc12>>O=c1c(O)c(-c2ccc(O)c(O)c2)oc2ccc(Cl)cc12,,ClCCl,,BrB(Br)Br,CO,test
US20040235826A1,C1COCCN1.CC(=O)c1ccc2[nH]c(-c3cc4ccccc4[nH]c3=O)cc2c1>>CC(c1ccc2[nH]c(-c3cc4ccccc4[nH]c3=O)cc2c1)N1CCOCC1,,C1COCCO1,CO,CC(=O)O,[BH3-]C#N.[Na+],test
US05556969,CC(C)CN1C(=O)C(N)N=C(C2CCCCCC2)c2ccccc21.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)CN1C(=O)C(NC(=O)Oc2ccc([N+](=O)[O-])cc2)N=C(C2CCCCCC2)c2ccccc21,,C1CCOC1,,CCN(CC)CC,,test
US05821241,Cc1ccc(S(=O)(=O)N[C@@H](CNC(=O)c2cc3n(n2)CCCN(CCC2CCN(C(=O)OC(C)(C)C)CC2)C3=O)C(=O)O)cc1>>Cc1ccc(S(=O)(=O)N[C@@H](CNC(=O)c2cc3n(n2)CCCN(CCC2CCNCC2)C3=O)C(=O)O)cc1,,ClCCl,,,,test
US20040110945A1,COC(=O)Cc1ccc2nc(Nc3cc(F)ccc3C)oc2c1F>>Cc1ccc(F)cc1Nc1nc2ccc(CC(=O)O)c(F)c2o1,,C1CCOC1,CO,[Na+].[OH-],,test
US06229011B1,CC(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)O.COC(=O)[C@H](Cc1ccc(N)cc1)NC(=O)c1c(C)cccc1Cl>>COC(=O)[C@H](Cc1ccc(NC(=O)[C@@H](CC(C)C)NC(=O)OC(C)(C)C)cc1)NC(=O)c1c(C)cccc1Cl,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05231103,COc1ccc(C(=O)C2CCCC2)cc1>>O=C(c1ccc(O)cc1)C1CCCC1,,ClCCl,,BrB(Br)Br,,test
US20060089371A1,COC(=O)[C@@H](N)Cc1ccccc1.O=Cc1c(Cl)ncnc1Cl>>COC(=O)[C@H](Cc1ccccc1)Nc1ncnc(Cl)c1C=O,,CO,,CCN(C(C)C)C(C)C,Cl,test
US06265597B1,CN(C)CCCN.C[Si](C)(C)Cl>>CN(C)CCCN[Si](C)(C)C,,CCOCC,,,,test
US20160046618A1,COc1cnc2c(Cl)nccc2c1>>Oc1cnc2c(Cl)nccc2c1,,ClCCCl,,BrB(Br)Br,,test
US07056932B2,BrCCCCCBr.Nc1ccc2c(c1)C(=O)NC2>>O=C1NCc2ccc(N3CCCCC3)cc21,,CC#N,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20120053188A1,Cc1ccccc1.Nc1ccc(-c2ccccc2)cc1NC(=O)CCCCCCC(=O)[O-]>>COC(=O)CCCCCCc1nc2ccc(-c3ccccc3)cc2[nH]1,,Cc1ccccc1,,CC(=O)O,,test
US20110190280A1,CS(=O)(=O)N1CCN(c2ccc([N+](=O)[O-])cn2)CC1>>CS(=O)(=O)N1CCN(c2ccc(N)cn2)CC1,[Pt],CCO,,,,test
US20040058904A1,COc1ccc(C(CC(=O)Nc2ccc(NC(=O)Nc3ccccc3C)cc2)NC(=O)c2ccc(C(=O)OC(C)(C)C)cc2)cc1OC>>COc1ccc(C(CC(=O)Nc2ccc(NC(=O)Nc3ccccc3C)cc2)NC(=O)c2ccc(C(=O)O)cc2)cc1OC,,ClCCl,,O=C(O)C(F)(F)F,,test
US04011335,CC(=CCOc1ccc2c(c1)OCO2)CCC=C(C)CC(C)C.O=C(OO)c1cccc(Cl)c1>>CC(=CCOc1ccc2c(c1)OCO2)CCC1OC1(C)CC(C)C,,ClCCl,,,,test
US20090048448A1,COc1cc(/C=C2\CCCN([C@@H](C)c3ccc(F)cc3)C2=O)ccc1-n1cnc(C)c1.CS(=O)(=O)O>>COc1cc(/C=C2\CCCN([C@@H](C)c3ccc(F)cc3)C2=O)ccc1-n1cnc(C)c1.CS(=O)(=O)O,,CCOC(C)=O,,O,,test
US20140249146A1,CS(=O)(=O)Cl.O=C1NCC(CCO)n2cc(I)cc21>>CS(=O)(=O)OCCC1CNC(=O)c2cc(I)cn21,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20090093486A1,Nc1nc(OCC(F)(F)F)cc(OCC(F)(F)F)n1.S=C(Cl)Cl>>FC(F)(F)COc1cc(OCC(F)(F)F)nc(N=C=S)n1,,C1COCCO1,,,,test
US05013736,CCOC(=O)CN.N#Cc1c2cccccc-2nc1Cl>>CCOC(=O)CNc1nc2cccccc-2c1C#N,,CCO,CN(C)C=O,CCN(CC)CC,Cl,test
US20120071460A1,CCOC(=O)CC(=O)c1ccccc1.NC(=NO)c1cc(F)ccc1F>>O=C(Cc1nc(-c2cc(F)ccc2F)no1)c1ccccc1,,Cc1ccccc1,,,,test
US04906624,COC(=O)/C=C/c1c(-c2ccccc2)ccnc1C>>COC(=O)CCc1c(-c2ccccc2)ccnc1C,[Pd],CCO,,,,test
US20110105476A1,CC(=O)Nc1ccc(C(=O)CCCl)cc1.O=C1NC(=O)c2ccccc21>>CC(=O)Nc1ccc(C(=O)CCN2C(=O)c3ccccc3C2=O)cc1,,CN(C)C=O,,[K],,test
US05712294,CCOC(=O)c1noc(C)c1C(=O)Nc1cc(C)cc(C)n1>>Cc1cc(C)nc(NC(=O)c2c(C(=O)O)noc2C)c1,,CO,O,Cl,[Li+].[OH-],test
US20070111984A1,COC(C)(OC)N(C)C.NC(=O)c1cc(F)ccc1Br>>CC(=NC(=O)c1cc(F)ccc1Br)N(C)C,,CO,,,,test
US06300352B1,C[C@H](Oc1ccc(B(O)O)cc1)[C@H](O)CCc1cccnc1.Cc1ccc(Br)cc1S(N)(=O)=O>>Cc1ccc(-c2ccc(O[C@@H](C)[C@H](O)CCc3cccnc3)cc2)cc1S(N)(=O)=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20100144757A1,Br[Mg]C1CC1.COCC(=O)C#C[Si](C)(C)C>>COCC(O)(C#C[Si](C)(C)C)C1CC1,,CCOCC,,CCOC(C)=O,,test
US04518597,CC1(C)OC(=O)Nc2ccc(OCCCCCl)cc21.Sc1ccc(Br)cc1>>CC1(C)OC(=O)Nc2ccc(OCCCCSc3ccc(Br)cc3)cc21,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20060019975A1,CCOS(=O)(=O)OCC.COc1cc2ncnc(N3CC(O)CC(c4ccc5ccccc5c4)C3)c2cc1OC>>CCOC1CC(c2ccc3ccccc3c2)CN(c2ncnc3cc(OC)c(OC)cc23)C1,,CN(C)C=O,,[H-].[Na+],,test
US07582626B2,CCOC(=O)C1CCCC1N(C(=O)CC1=NS(=O)(=O)c2cc(NS(C)(=O)=O)ccc2N1)C(C)C>>CC(C)N1C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)[C@@H]2CCC[C@@H]21,,CCO,,C,C[O-].[Na+],test
US20050043309A1,O=C1CCc2cccc(N3CCN(CCCCOc4ccc5ccc(=O)[nH]c5n4)CC3)c2C1>>O=c1ccc2ccc(OCCCCN3CCN(c4cccc5c4CC(O)CC5)CC3)nc2[nH]1,,CO,,[BH4-].[Na+],,test
US20130040978A1,CC(C)I.COC(=O)c1n[nH]c2cccc(Br)c12>>COC(=O)c1nn(C(C)C)c2cccc(Br)c12,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110237588A1,CN(C)C=CC(=O)c1cccs1.NN>>c1csc(-c2cc[nH]n2)c1,,CCO,,O,,test
US06326359B1,COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(COS(C)(=O)=O)nc32)[C@H](O)[C@@H]1O.Sc1ccccc1>>COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CSc4ccccc4)nc32)[C@H](O)[C@@H]1O,,C1CCOC1,,CCN(CC)CC,,test
US20150299156A1,CS(=O)(=O)Cl.Cc1cc(C)c(C2=C(OC(=O)C(C)(C)C)CC(C(C)CO)OC2=O)c(C)c1>>Cc1cc(C)c(C2=C(OC(=O)C(C)(C)C)CC(C(C)COS(C)(=O)=O)OC2=O)c(C)c1,,C1CCOC1,,CCN(CC)CC,,test
US04113943,CCOC(=O)C(=O)NC(C(=O)OC(c1ccccc1)c1ccccc1)c1ccccc1.N>>NC(=O)C(=O)NC(C(=O)OC(c1ccccc1)c1ccccc1)c1ccccc1,,CCO,,,,test
US20150291598A1,CNc1ccc(C#N)cc1.O=C(O)c1cn2c(Br)cnc2cn1>>CN(C(=O)c1cn2c(Br)cnc2cn1)c1ccc(C#N)cc1,CN(C)C=O,Cc1ccccc1,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20160237044A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2ccc(-c3ccc(S(N)(=O)=O)cc3)cc2)C(=O)Nc2ccc(-c3nnc(Cl)[nH]3)cc2)CC1.Cl>>Cl.NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2ccc(-c3ccc(S(N)(=O)=O)cc3)cc2)C(=O)Nc2ccc(-c3nnc(Cl)[nH]3)cc2)CC1,,C1COCCO1,,CC#N,,test
US20120302586A1,CCO.Cc1cc(Nc2ccc(C(F)(F)F)cc2)n2nc(S(C)(=O)=O)nc2n1>>CCOc1nc2nc(C)cc(Nc3ccc(C(F)(F)F)cc3)n2n1,,CCO,,C,C[O-].[Na+],test
US20110257151A1,CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc(N2CCOCC2)c1.CS(N)(=O)=O>>CC1(C)Cc2cc(C(=O)NS(C)(=O)=O)ccc2NC1c1cccc(N2CCOCC2)c1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,[H-].[Na+],test
US05155122,CC(C)(C)c1cc(C(=O)NN(C(=O)O)C(C)(C)C)cc(C(C)(C)C)c1O>>CC(C)(C)c1cc(C(=O)NN)cc(C(C)(C)C)c1O,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20060089392A1,CCOC(=O)C1CCNCC1.CN(C)C(=O)c1cc(Cl)ccc1[N+](=O)[O-]>>CCOC(=O)C1CCN(c2ccc([N+](=O)[O-])c(C(=O)N(C)C)c2)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110015157A1,C[C@@H](c1ccc(-c2ccc(F)cc2F)cc1)N1CC[C@](CCC#N)(c2ccc(F)cc2)OC1=O.C[Sn](C)(C)N=[N+]=[N-]>>C[C@@H](c1ccc(-c2ccc(F)cc2F)cc1)N1CC[C@](CCc2nnn[nH]2)(c2ccc(F)cc2)OC1=O,,Cc1ccccc1,,,,test
US20130005750A1,CC1c2c(ncnc2Oc2ccc3c(ccn3C(=O)Nc3cccc(C(F)(F)F)c3)c2)CN1C(=O)OC(C)(C)C>>CC1NCc2ncnc(Oc3ccc4c(ccn4C(=O)Nc4cccc(C(F)(F)F)c4)c3)c21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040171838A1,BrCc1ccccc1.COc1ccnc(C(=O)N[C@H]2COC(=O)[C@H](Cc3ccccc3)[C@@H](OC(=O)C(C)C)[C@H](C)OC2=O)c1O>>COc1ccnc(C(=O)N[C@H]2COC(=O)[C@H](Cc3ccccc3)[C@@H](OC(=O)C(C)C)[C@H](C)OC2=O)c1OCc1ccccc1,,CC(C)=O,ClCCl,[I-].[K+],O=C([O-])O.[Na+],test
US05808062,Cc1cc(-c2cc(O)c(SCc3ccccc3)c(=O)o2)cc(C)c1O[Si](C)(C)C(C)(C)C>>Cc1cc(-c2cc(O)c(SCc3ccccc3)c(=O)o2)cc(C)c1O,,C1CCOC1,,Cl,,test
US04344959,COC(C)(C)CCCC(C)CC(O)CC(=O)C1COC(=O)C1>>COC(C)(C)CCCC(C)C/C=C/C(=O)C1COC(=O)C1,,CO,,Cl,O,test
US20120178744A1,CC(C)(C)OC(=O)N1CCC(c2cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n3ncc(I)c3n2)CC1.CC1(C)OB(c2ccc(-c3ccccc3)nc2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC(c2cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n3ncc(-c4ccc(-c5ccccc5)nc4)c3n2)CC1,,COCCOC,O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20090215728A1,COC(OC)N(C)C.NS(=O)(=O)c1ccc(Br)cc1>>CN(C)C=NS(=O)(=O)c1ccc(Br)cc1,,CN(C)C=O,,O,,test
US04618359,O=C(Cl)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].OC1CCOC1>>O=C(OC1CCOC1)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-],,Cc1ccccc1,,CCN(CC)CC,,test
US20160024091A1,C=C(C)CC1(C(=O)OCC)CCN(C(=O)OC(C)(C)C)CC1.O=[Os](=O)(=O)=O>>CCOC(=O)C1(CC(C)=O)CCN(C(=O)OC(C)(C)C)CC1,O=[Os](=O)(=O)=O,C1COCCO1,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US06759547B1,CCC(=O)c1cc2c(cc1OC)C(C)(C)CCC2(C)C>>CCC(=O)c1cc2c(cc1O)C(C)(C)CCC2(C)C,,ClCCl,,BrB(Br)Br,,test
US20120059028A1,CCCI.COC(=O)Cc1c(C)nc2sc3c(c2c1Cc1cccc(OC)c1)CCCC3>>CCCC(C(=O)OC)c1c(C)nc2sc3c(c2c1Cc1cccc(OC)c1)CCCC3,,CN(C)C=O,,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US04230628,CO.COC(=O)CCCCCCCCCCCCCCCNc1ccc(C(=O)O)cc1>>COC(=O)CCCCCCCCCCCCCCCNc1ccc(C(=O)OC)cc1,,CO,,CCOCC,FB(F)F,test
US06262095B1,NC1=C(Cl)C(=O)c2ccccc2C1=O.O=C(Cl)c1ccc(Cl)cc1>>O=C1c2ccccc2C(=O)c2oc(-c3ccc(Cl)cc3)nc21,,C1COCCO1,,O=S(=O)(O)O,,test
US04716159,O=P(Cl)(Cl)Cl.O=c1[nH]c2cc(-c3ccccc3)nnc2c2ccccc12>>Clc1nc2cc(-c3ccccc3)nnc2c2ccccc12,,O=P(Cl)(Cl)Cl,,ClP(Cl)(Cl)(Cl)Cl,,test
US04956359,C#CCN.Cc1cccc(OC2CN(C(=O)Cl)C2)c1>>C#CCNC(=O)N1CC(Oc2cccc(C)c2)C1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20100274003A1,CCN(CC)CC.CS(=O)(=O)Cl.OC1CN(Cc2ccc(F)cc2)C1>>CC(=O)SC1CN(Cc2ccc(F)cc2)C1,,ClCCl,,Cl,O,test
US20090023724A1,CC(Nc1nc(-c2cccc3ncccc23)ccc1N)c1ccccc1.CC(Nc1nc(-c2cccc3ncccc23)ccc1[N+](=O)[O-])c1ccccc1>>CC(c1ccccc1)n1c(=O)[nH]c2ccc(-c3cccc4ncccc34)nc21,[Pd],,,CCO,,test
US05084085,Cc1nn(-c2cc(O)c(Cl)cc2F)c(=O)n1C(F)F.N#Cc1ccc(F)cc1>>Cc1nn(-c2cc(Oc3ccc(C#N)cc3)c(Cl)cc2F)c(=O)n1C(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04393221,CC(=O)OC1(C(C)=O)CC2=C(C(=O)C=CC2=O)C2(C1)OCCO2.CC(=O)O[C@@H]1c2ccccc2[C@H]1OC(C)=O>>CC(=O)OC1c2ccccc2C(OC(C)=O)C2C(=O)C3=C(CC(OC(C)=O)(C(C)=O)CC34OCCO4)C(=O)C12,,Cc1ccccc1,,,,test
US20020052397A1,CC1(C)OC[C@@H](COc2cccc(CC(=O)O)c2)O1.Cn1ccc2ccccc21.O=C(Cl)C(=O)Cl>>Cn1cc(C2=C(c3cccc(OC[C@@H]4COC(C)(C)O4)c3)C(=O)OC2=O)c2ccccc21,,CCOCC,ClCCl,CCN(CC)CC,,test
US20040127574A1,CCOC(=O)C(Cc1cccc(OC(F)(F)C(F)F)c1)C(=O)c1ccc(Br)cc1>>CCOC(=O)C(Cc1cccc(OC(F)(F)C(F)F)c1)C(O)c1ccc(Br)cc1,,CCOCC,,Cl,[BH4-].[Na+],test
US05462944,CC(C)(C)C1CCC2(CC1)OCC(CN1C(=O)c3ccccc3C1=O)O2>>CC(C)(C)C1CCC2(CC1)OCC(CN)O2,,CCO,,NN,O,test
US05639914,Cc1cc(-c2ccc(I)c(C)c2)ccc1I.c1ccc(Nc2ccccc2)cc1>>Cc1cc(-c2ccc(N(c3ccccc3)c3ccccc3)c(C)c2)ccc1I,[Cu],O=[N+]([O-])c1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20090247591A1,CN(C)Cc1c[nH]c2ccccc12.O=Cc1ccccc1>>O=C(Cc1c[nH]c2ccccc12)c1ccccc1,,CN(C)C=O,O,Cl,,test
US20160046581A1,CC(C)(C)OC(=O)c1ccc(NC(=O)C(Cc2ccccc2)n2ccc(-c3cc(Cl)ccc3[N+](=O)[O-])cc2=O)c(N)c1>>CC(C)(C)OC(=O)c1ccc2[nH]c(C(Cc3ccccc3)n3ccc(-c4cc(Cl)ccc4[N+](=O)[O-])cc3=O)nc2c1,,CC(=O)O,,,,test
US06462036B1,CCOC(=O)c1cccc(OC)c1.NN=C1CCc2ccccc21>>COc1cccc(-c2n[nH]c3c2Cc2ccccc2-3)c1,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US03956297,COC(CN)OC.FC(F)(F)c1ccc2c(c1)NC(=S)c1ccccc1N2>>COC(CNC1=Nc2cc(C(F)(F)F)ccc2Nc2ccccc21)OC,,CCCCO,,,,test
US20110190257A1,O=Cc1c(F)cccc1F.O=[N+]([O-])O>>O=Cc1c(F)ccc([N+](=O)[O-])c1F,,O=S(=O)(O)O,,,,test
US20030027840A1,CCCCC12CCC(=O)C(c3ccc(O)cc3)=C1c1ccc(OC)cc1C2.ClCCN1CCCCC1>>CCCCC12CCC(=O)C(c3ccc(OCCN4CCCCC4)cc3)=C1c1ccc(OC)cc1C2,,CC(C)=O,CCOC(C)=O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20080064753A1,C=C[C@@]1(C)CC=C2C(CCC3[C@](C)(C(=O)O)CCC[C@@]23C)C1.NC1CCCCC1>>C=C[C@@]1(C)CC=C2C(CCC3[C@](C)(C(=O)O)CCC[C@@]23C)C1.[NH-]C1CCCCC1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20070124152A1,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(C2CC2)c1=O.NCCO>>O=C(NCCO)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(C2CC2)c1=O,,CCO,,,,test
US20140221374A1,CCC(C)(CC)C(N)=S.O=C(CBr)c1ccnc(Cl)n1>>CC(C)(C)c1nc(-c2ccnc(Cl)n2)cs1,,CCO,,,,test
US20110212918A1,CS(=O)(=O)Cl.Nc1cc(NC(=O)OCc2ccccc2)cnc1SCc1ccccc1>>CS(=O)(=O)Nc1cc(NC(=O)OCc2ccccc2)cnc1SCc1ccccc1,,c1ccncc1,,,,test
US20090253689A1,COC(=O)c1ccnc(N)c1.O=C1CCC(=O)N1Br>>COC(=O)c1cc(N)ncc1Br,,CCOC(C)=O,CN(C)C=O,,,test
US20040092582A1,CCOc1cc(C(O)C(C)C)cc2c1OC(C)(C)C2.COC(=O)c1cccc(C#N)c1>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(C(=O)OC)c1)=NC(C)(C)C2,,Cc1ccccc1,O,CC(=O)O,O=S(=O)(O)O,test
US20160237090A1,CC1Cn2ncc(-c3ccc(F)cc3)c2CN1C(=O)OC(C)(C)C>>CC1Cn2ncc(-c3ccc(F)cc3)c2CN1,,CO,Cl,,,test
US20110098324A1,CCOC(=O)CNC(=O)c1c(O)c(C(=O)OC)c(O)n(Cc2ccc(Cl)cc2Cl)c1=O.Nc1ccccc1C(F)(F)F>>O=C(O)CNC(=O)c1c(O)c(C(=O)Nc2ccccc2C(F)(F)F)c(O)n(Cc2ccc(Cl)cc2Cl)c1=O,,ClC(Cl)Cl,,,,test
US20150175623A1,CN(C)CCCl.c1cn[nH]c1>>CN(C)CCn1cccn1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20150322076A1,COC(=O)c1ccc(NC(=O)CNC(=O)OC(C)(C)C)c(F)c1.O=C(O)C(F)(F)F>>COC(=O)c1ccc(NC(=O)CN)c(F)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20130029980A1,CCOC(=O)C(C(=O)OCC)(C(=O)OCC)[C@@H](C)c1ccc(Cl)cc1>>C[C@H](CC(=O)O)c1ccc(Cl)cc1,,CO,,[Na+].[OH-],,test
US20060004007A1,CC(=O)N1CCc2ccc(N)cc21.Cc1cc2c(Nc3ccc(C)c(O)c3)ncnn2c1>>CC(=O)N1CCc2ccc(Nc3ncnn4cccc34)cc21,,CC(C)O,ClCCl,,,test
US20070197536A1,CCBr.O=c1ccc(-c2cccc(Cl)c2)n[nH]1>>CCn1nc(-c2cccc(Cl)c2)ccc1=O,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US04808572,CCCCCCCCCc1ccccc1/C=C/CCCCO.CCN(CC)S(F)(F)F>>CCCCCCCCCc1ccccc1/C=C/CCCCF,,ClCCl,,O,,test
US05624923,CCOc1ccccc1C(=O)Cl.Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1>>CCOc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1,,ClCCl,,CCN(CC)CC,,test
US05005572,Cc1cc(C2(c3ccc(O)c(C)c3)OS(=O)(=O)c3ccccc32)ccc1O.O=C1CCC(=O)N1Br.[OH-]>>CCCC[N+](CCCC)(CCCC)CCCC.[OH-],,[Na+],[OH-],Cl,,test
US05929097,COC(=O)c1cc(C)cc(Br)c1NS(=O)(=O)c1ccc(OC)cc1.ClCc1cccnc1>>COC(=O)c1cc(C)cc(Br)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20160145267A1,CC(C)(C)[Si](C)(C)OC(C#N)C#N.CCOc1cc(F)c(Cn2nc(C(=N)N)c(C)c2C2CC2)c(F)c1>>CCOc1cc(F)c(Cn2nc(-c3nc(N)c(O)c(N)n3)c(C)c2C2CC2)c(F)c1,,CC(C)(C)O,O,Cl,CC(C)(C)[O-].[K+],test
US20130137675A1,CC(=O)C(=NNc1cccc(C(F)(F)F)c1)C(=O)c1occc1Br>>CC(=O)c1nn(-c2cccc(C(F)(F)F)c2)c2ccoc2c1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070037888A1,CN.COC(=O)c1cc(Nc2cc(C)[nH]n2)nc(N2CCCC2c2cc(-c3ccccn3)no2)n1>>CNC(=O)c1cc(Nc2cc(C)[nH]n2)nc(N2CCCC2c2cc(-c3ccccn3)no2)n1,,CO,,,,test
US04317823,Cc1nn(C)c(C(=O)Oc2ccccc2)c1Nc1ccccc1[N+](=O)[O-]>>Cc1nn(C)c2c1Nc1ccccc1NC2=O,[Pd],Cc1ccccc1,,CC(=O)O,,test
US20040006069A1,Cc1ccccc1C(=O)NC[C@H](C)c1ccccc1>>Cc1ccccc1C1=NC[C@H](C)c2ccccc21,,ClCCl,,[NH4+].[OH-],,test
US20090137580A1,Cn1ccc2ncnc(O)c21.O=[N+]([O-])c1ccc(CBr)cc1>>Cn1ccc2ncnc(OCc3ccc([N+](=O)[O-])cc3)c21,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20060235030A1,C1CCN(C2CCNCC2)CC1.CS(=O)c1nc(Cl)c2c(n1)N(c1c(F)cccc1F)C(=O)NC2>>O=C1NCc2c(Cl)nc(N3CCC(N4CCCCC4)CC3)nc2N1c1c(F)cccc1F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150175601A1,CC(=O)OCc1ccc2cnc(Cl)nc2c1Br.CN1CCN(c2ccc(N)cc2)CC1>>CC(=O)OCc1ccc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2c1Br,,CCCCO,,O=C(O)C(F)(F)F,,test
US20060258721A1,CN(C(=O)OC(C)(C)C)C1CC=C(c2c[nH]c3ccc(NC(=N)c4cccs4)cc23)CC1>>CNC1CC=C(c2c[nH]c3ccc(NC(=N)c4cccs4)cc23)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160068531A1,CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(=O)CCSC>>CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(O)CCSC,,CO,,[BH4-].[Na+],,test
US20120028971A1,CC(N)CCCC1(C(=O)OC(C)(C)C)CC1.O=C(O)C(c1ccc(CN2N=C(c3ccccc3)OCC2=O)cc1)C1CCCC1>>CC(CCCC1(C(=O)OC(C)(C)C)CC1)NC(=O)C(c1ccc(CN2N=C(c3ccccc3)OCC2=O)cc1)C1CCCC1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160024097A1,Cc1ccc(C#N)c(S(=O)(=O)Cl)c1.Nc1ccc(-c2cc3[nH]nc(N)c3cn2)cc1>>Cc1ccc(C#N)c(S(=O)(=O)Nc2ccc(-c3cc4[nH]nc(N)c4cn3)cc2)c1,,ClCCl,c1ccncc1,Cl,,test
US06099593,Cc1cc(Cl)n2ncc([N+](=O)[O-])c2n1.NCCO>>Cc1cc(NCCO)n2ncc([N+](=O)[O-])c2n1,,CCO,,,,test
US20130018033A1,CCCS(=O)(=O)Nc1ccc(Cl)c(N)c1Cl.O=C(Cl)c1cccc2c(Cl)ncnc12>>CCCS(=O)(=O)Nc1ccc(Cl)c(NC(=O)c2cccc3c(Cl)ncnc23)c1Cl,,ClC(Cl)Cl,,c1ccncc1,,test
US20120264737A1,CO.O=C(O)CC1CCOC1>>COC(=O)CC1CCOC1,,CCOCC,,O=S(=O)(O)O,,test
US20130053308A1,Nc1cc(Cl)nc(Cl)n1.O=C1CCC(=O)N1Br>>Nc1nc(Cl)nc(Cl)c1Br,,CN(C)C=O,,O,,test
US20110118330A1,COC(=O)CC[C@H](O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)C(=O)OC>>CC(C)(C)[Si](O[C@H](CO)CCCO)(c1ccccc1)c1ccccc1,Cl,CCOCC,,CO,[BH4-].[Li+],test
US05604253,COC(=O)C(C)(C)Cc1c(C)n(Cc2ccc(Br)cc2)c2ccc(OC)cc12>>COc1ccc2c(c1)c(CC(C)(C)C(=O)O)c(C)n2Cc1ccc(Br)cc1,,CCO,,[K+].[OH-],,test
US05559140,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)[C@H](N)CO>>CC(C)[C@@H](CO)NC(=O)OC(C)(C)C,,CO,,,,test
US20040157904A1,Cc1cc(F)ccc1C(=O)CC#N.Cc1ccccc1NN>>Cc1cc(F)ccc1-c1cc(N)n(-c2ccccc2C)n1,,Cc1ccccc1,,Cl,,test
US20100152190A1,COC(=O)CCCc1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)cc1>>CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(CCCC(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20030130270A1,COC(=O)[C@H](N)Cc1ccccc1.CS(=O)(=O)OS(C)(=O)=O>>COC(=O)[C@@H](Cc1ccccc1)NS(C)(=O)=O,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20090233903A1,C[Si](C)(C)CCOCn1ccc2c(-c3cn[nH]c3)ncnc21.N#CC=C1CC(CC#N)(CC#N)C1>>C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C4(CC#N)CC(CC#N)(CC#N)C4)c3)ncnc21,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20090202483A1,BrCCCBr.Brc1ccc2c(c1)Cc1cc(Br)ccc1-2>>Brc1ccc2c(c1)C1(CCC1)c1cc(Br)ccc1-2,,CS(C)=O,O,[K+].[OH-],,test
US20090053597A1,CCCCP(CCCC)CCCC.COCBr>>CCCC[P+](CCCC)(CCCC)COC.[Br-],,CCCCCC,,,,test
US20100197674A1,CCOC(=O)C(=O)C(=O)OCC.Nc1cccnc1Nc1ccccc1>>CCOC(=O)c1nc2cccnc2n(-c2ccccc2)c1=O,,CCO,,,,test
US20110306587A1,Clc1ncc(Br)c(C2CNC2)n1.O=C(O)c1nc2ccccc2[nH]1>>O=C(c1nc2ccccc2[nH]1)N1CC(c2nc(Cl)ncc2Br)C1,,ClCCl,,Cl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070281918A1,C=C1CN(C(=O)C(F)(F)F)CCc2nc(OC)ccc21>>COc1ccc2c(n1)CCN(C(=O)C(F)(F)F)CC2C,[Pd],CO,,,,test
US20100240638A1,COC(=O)CCCN(C)CCCCO>>COC(=O)CCCN(C)CCCC=O,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US06136848,CCI.O=C(O)c1ccc2oc(-c3ccc(OCc4ccccc4)cc3)cc(=O)c2c1>>CCOC(=O)c1ccc2oc(-c3ccc(OCc4ccccc4)cc3)cc(=O)c2c1,,CN(C)P(=O)(N(C)C)N(C)C,,O,[H-].[Na+],test
US05686478,COC(=O)c1ccc(O[Si](C)(C)C(C)(C)C)cc1>>CC(C)(C)[Si](C)(C)Oc1ccc(CO)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080027049A1,NC1CCc2oc3ccccc3c2C1.O=C(Cl)Cc1ccccc1>>O=C(Cc1ccccc1)Nc1ccc2oc3c(c2c1)CCCC3,,C1CCOC1,,CCN(CC)CC,,test
US06521643B1,CC(=O)N(C)C.Cc1cc(N(C)C)ccn1>>CC(=O)Cc1cc(N(C)C)ccn1,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US20150291563A1,CSc1cccc(B(O)O)c1.Fc1ccc(N2N=C(C(F)(F)C(F)(F)F)CC2c2ccc(Br)s2)c(F)c1>>CSc1cccc(-c2ccc(C3CC(C(F)(F)C(F)(F)F)=NN3c3ccc(F)cc3F)s2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20120010187A1,COC(=O)c1ccc(Br)o1.OB(O)c1cccs1>>COC(=O)c1ccc(-c2cccs2)o1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US20160115125A1,COC(=O)c1c(Cl)c(S(=O)(=O)Cl)cn1C.NC1(C(F)(F)F)CCC1>>COC(=O)c1c(Cl)c(S(=O)(=O)NC2(C(F)(F)F)CCC2)cn1C,,CC#N,,CCN(C(C)C)C(C)C,,test
US20090275578A1,CC(N)c1ccc(OC(F)(F)F)cc1.COC(=O)c1c(Cl)cc(Br)cc1CBr>>CC(c1ccc(OC(F)(F)F)cc1)N1Cc2cc(Br)cc(Cl)c2C1=O,,CCCCCC,Cc1ccccc1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20140088124A1,CCOC(=O)C1CCC(O)CC1.Oc1ccncc1>>CCOC(=O)[C@@H]1CC[C@H](Oc2ccncc2)CC1,,C1CCOC1,CCO,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120053173A1,CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3ccc(NC(C)=O)cc3c2C)C2CCCCC2)cc1>>CC(=O)Nc1ccc2oc(C(Nc3ccc(C(=O)N(C)CCC(=O)O)cc3)C3CCCCC3)c(C)c2c1,,CCO,,C1CCOC1,[Li+].[OH-],test
US04471116,CS(=O)(=O)Cl.OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1>>ClCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1,,ClCCl,,CCN(CC)CC,,test
US20100120706A1,C#Cc1cccnc1.Nc1ncnc2c1nc(Br)n2CCO>>Nc1ncnc2c1nc(C#Cc1cccnc1)n2CCO,[Cu]I,CCN(CC)CC,CN(C)C=O,,,test
US20140213580A1,COCCC(=O)N1CCN(c2nc(C3CC3)c(-c3ccc(C(=O)O)cc3)cc2C#N)C[C@H]1C.C[NH2+]OC>>COCCC(=O)N1CCN(c2nc(C3CC3)c(-c3ccc(C(=O)N(C)OC)cc3)cc2C#N)C[C@H]1C,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100286430A1,CCCCOc1cc(/C=C(\OC)C(=O)OC)ccc1OS(=O)(=O)C(F)(F)F>>CCCCOc1cc(/C=C(\OC)C(=O)O)ccc1OS(=O)(=O)C(F)(F)F,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20080076760A1,CC(C)=CC(=O)O.Nc1ccccc1N>>CC1(C)CC(=O)Nc2ccccc2N1,,ClC(Cl)Cl,,,,test
US20150368182A1,CCCCCCO.CN1CCCC1=O.O=S(=O)(F)F>>CCCCCC[N+]1(C)CCCC1.O=S(=O)([O-])F,,CC#N,,N,,test
US20020028810A1,O=C(O)c1cc2cc(Cl)ccc2[nH]1.[F-]>>O=C(F)c1cc2cc(Cl)ccc2[nH]1,,CC#N,,c1ccncc1,,test
US20140094459A1,O=[N+]([O-])c1ccc(Oc2cccc(F)c2F)cc1>>Nc1ccc(Oc2cccc(F)c2F)cc1,[Ni],CO,,NN,O,test
US20100075944A1,CNC1CCN(C)CC1.O=C(Oc1ccccc1)N(C(=O)Oc1ccccc1)c1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2)ccn1>>CN1CCC(N(C)C(=O)Nc2cc(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3)ccn2)CC1,,CN(C)C=O,,,,test
US05962457,CC(=O)Nc1ccsc1C(=O)O.Nc1cccnc1Cl>>Cc1nc2ccsc2c(=O)n1-c1cccnc1Cl,,c1ccncc1,,ClP(Cl)Cl,,test
US20140107122A1,CCN(c1cc(C#CC2CCN(C(=O)OC(C)(C)C)CC2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1>>CCN(c1cc(C#CC2CCNCC2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1,,ClCCl,,C1COCCO1,Cl,test
US20150051395A1,COC(=O)[C@H](Cc1ccc(-n2c(=O)[nH]c3cnccc3c2=O)cn1)NC(=O)OC(C)(C)C.COS(=O)(=O)c1ccc(C)cc1>>COC(=O)[C@H](Cc1ccc(-n2c(=O)c3ccncc3n(C)c2=O)cn1)NC(=O)OC(C)(C)C,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05032588,COc1ccc2cc(C(C)C(Br)C(=O)Br)ccc2c1.NC(=S)c1ccccc1>>COc1ccc2cc(C(C)c3sc(-c4ccccc4)nc3O)ccc2c1,,Cc1ccccc1,,c1ccncc1,,test
US20080139639A1,CCOC(=O)c1cn(S(=O)(=O)c2ccccc2)c(-c2ccccc2)c1F>>O=S(=O)(c1ccccc1)n1cc(CO)c(F)c1-c1ccccc1,,C1CCOC1,Cc1ccccc1,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20070161574A1,CC(C)(C)OC(=O)NC(C(=O)O)C(C)(C)C.COC(=O)C(N)C1CCCCC1>>COC(=O)C(NC(=O)C(NC(=O)OC(C)(C)C)C(C)(C)C)C1CCCCC1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050032829A1,CCCCc1nc2c(c(C)c(C)n3nnnc23)n1CC(C)(C)NC(=O)OC(C)(C)C>>CCCCc1nc2c(c(C)c(C)n3nnnc23)n1CC(C)(C)N,,CCO,,Cl,,test
US20150072969A1,CCOC(=O)C=C1COC1.OB(O)c1ccc(O)c(F)c1>>CCOC(=O)CC1(c2ccc(O)c(F)c2)COC1,,C1COCCO1,,[K+].[OH-],,test
US07576074B2,COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1O>>Cl.Nc1ncnc2ccccc12,,CC(=O)N(C)C,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US03957819,NCCCO.O=C1Nc2ccccc2C1(O)c1ccccc1>>OCCCNC1=Nc2ccccc2C1(O)c1ccccc1,,Cc1ccccc1C,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20080009513A1,COC(=O)C1C(=O)CCN(N2CCCCC2)C1=O>>O=C1CCN(N2CCCCC2)C(=O)C1,,CC(=O)O,,,,test
US20060160876A1,CCOC(=O)CC1(CC)OCCc2c1[nH]c1c(Br)cccc21>>CCC1(CCO)OCCc2c1[nH]c1c(Br)cccc21,,C1CCOC1,,[BH4-].[Li+],,test
US20050288305A1,CCOC(=O)C1(NC(=O)c2cncnc2)CCC1>>O=C(NC1(C(=O)O)CCC1)c1cncnc1,,C1CCOC1,O,[Na+].[OH-],,test
US20030055263A1,COC(=O)c1ccccc1C(=O)Nc1nc(-c2ccc3ccccc3c2)cs1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COC(=O)c1ccccc1C(=S)Nc1nc(-c2ccc3ccccc3c2)cs1,,Cc1ccccc1C,,,,test
US20150274777A1,CC(C)(O)C#N.CCCC[C@@H](C=O)NC(=O)OC(C)(C)C>>CCCC[C@H](NC(=O)OC(C)(C)C)C(O)C#N,,CCOCC,ClCCl,CCN(CC)CC,,test
US20140323501A1,CC(=O)NC(CO)(CO)CCc1ccc(Oc2ccc(-c3coc(C(C)C)n3)cc2)cc1>>CC(C)c1nc(-c2ccc(Oc3ccc(CCC(N)(CO)CO)cc3)cc2)co1,,CO,,[Na+].[OH-],,test
US20150258074A1,CC(=O)OCc1nc(Cl)cc2c1c(OCCO)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>OCCOc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(Cl)nc(CO)c12,,CO,ClCCl,C[O-].[Na+],,test
US20120202776A1,COc1cc(P(C)(C)=O)ccc1N.Cc1cnc(Cl)nc1Nc1ccccc1S(=O)(=O)C(C)C>>COc1cc(P(C)(C)=O)ccc1Nc1ncc(C)c(Nc2ccccc2S(=O)(=O)C(C)C)n1,,COCCO,,Cl,,test
US06858739B2,COc1ccc(-c2cc3cc(F)c(F)cc3[nH]2)cc1N.O=C(O)c1cccc(N=C=S)c1>>COc1ccc(-c2cc3cc(F)c(F)cc3[nH]2)cc1NC(=S)Nc1cccc(C(=O)O)c1,,C1CCOC1,,CCOC(C)=O,,test
US05244863,CCOC(=O)N=C1SC(CBr)CN1c1cccc(C(F)(F)F)c1>>C=C1CN(c2cccc(C(F)(F)F)c2)C(=NC(=O)OCC)S1,,CC(C)(C)O,,CC(C)(C)[O-].[K+],,test
US20160175289A1,C[C@H](Cc1c[nH]c2ccccc12)NCC(F)F.O=Cc1c(F)cc(I)cc1F>>C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(I)cc2F)N1CC(F)F,,Cc1ccccc1,,CC(=O)O,,test
US20090111848A1,CC(=O)c1ccc(F)c(N(C)S(C)(=O)=O)c1.COC(OC)N(C)C>>CN(C)C=CC(=O)c1ccc(F)c(N(C)S(C)(=O)=O)c1,,CCCCCC,,,,test
US20110021537A1,CCCCOC(=O)NC1CCN(C(=O)OCc2ccccc2)CC1>>CCCCOC(=O)NC1CCNCC1,[Pd],CCO,,,,test
US20080200675A1,CC(=O)O.CCO.CCOC(=O)C(=C(Cl)Cl)c1c(F)cc(F)cc1F>>CCOC(=O)C(C(=O)OCC)c1c(F)cc(F)cc1F,,CCO,,C,C[O-].[Na+],test
US05198434,CCc1cc(OCc2ccc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc2)c2c(n1)CCCN2C(=O)C(F)(F)F>>CCc1cc(OCc2ccc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc2)c2c(n1)CCCN2,,CO,,[K+].[OH-],,test
US20070185136A1,Fc1ccc(F)cc1.O=Cc1cc(Cl)ccc1[N+](=O)[O-]>>O=[N+]([O-])c1ccc(Cl)cc1C(O)c1cc(F)ccc1F,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20140315917A1,CC1CNC(=O)N1C1CCOCC1.Cn1cc(-c2cc(Oc3ccc(N)nc3)ccn2)cn1.O=C(Cl)Cl>>CC1CN(C(=O)Nc2ccc(Oc3ccnc(-c4cnn(C)c4)c3)cn2)C(=O)N1C1CCOCC1,,ClCCl,,c1ccncc1,,test
US20020045644A1,CS(=O)(=O)c1ccc(-c2oc(C=O)cc(=O)c2-c2ccc(Cl)cc2)cc1>>CS(=O)(=O)c1ccc(-c2cc(=O)cc(CO)o2)cc1,,CO,,[BH4-].[Na+],,test
US06103737,CCN(c1nc(C)nc(Cl)n1)c1ccc(C(C)C)cc1Br.OB(O)c1ccc(Cl)cc1Cl>>CCN(c1nc(C)nc(-c2ccc(Cl)cc2Cl)n1)c1ccc(C(C)C)cc1Br,,CCOC(C)=O,c1ccccc1,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20100137386A1,Fc1ccc(N=C=S)cc1.N#CC(N)C(N)=O>>NC(=O)c1nc(Nc2ccc(F)cc2)sc1N,,CCOC(C)=O,,,,test
US07375227B2,CCOC(=O)C1(Cc2ccccc2)CCN(Cc2ccccc2)CC1>>CCOC(=O)C1(Cc2ccccc2)CCNCC1,[Pd],CO,,Cl,,test
US20050131001A1,CCSc1cc(C)nc(SCC)c1NC(=O)CBr.Sc1nc2ccccc2o1>>CCSc1cc(C)nc(SCC)c1NC(=O)CSc1nc2ccccc2o1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060025445A1,NCc1ccc(C(F)(F)F)cc1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(NCc1ccc(C(F)(F)F)cc1)c1ccccc1,,CC#N,,CCN(CC)CC,,test
US20160039838A1,C1CO[C@H]2CNC[C@H]2O1.COc1cc2ncnc(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)c2cc1NC(=O)/C=C/CBr>>COc1cc2ncnc(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)c2cc1NC(=O)/C=C/CN1C[C@H]2OCCO[C@H]2C1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,O,test
US05239121,C=O.COC(=O)Cc1ccccc1>>COC(=O)C(CO)c1ccccc1,,CS(C)=O,,O=C([O-])O.[Na+],,test
US05210092,CCCC(=O)Nc1nc(C)cc(C)c1[N+](=O)[O-].Cc1ccc(C#N)n1-c1ccc(COS(C)(=O)=O)cc1>>CCCC(=O)N(Cc1ccc(-n2c(C)ccc2C#N)cc1)c1nc(C)cc(C)c1[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],,test
US04069332,CCOC(=O)C(N)=S.NO>>CCOC(=O)/C(N)=N/O,,CCO,,Cl,[Na],test
USH0002007H1,CCOC(=O)N1CCN(C(c2ccc(Cl)cc2)c2ccccc2Cl)CC1>>Clc1ccc(C(c2ccccc2Cl)N2CCNCC2)cc1,,C1CCOC1,,CO,[Na+].[OH-],test
US04478749,O=C(N[C@H]1CNC1=O)OCc1ccccc1.[O-]Cl>>O=C(N[C@H]1CN(Cl)C1=O)OCc1ccccc1,,ClCCl,O,[Na+].[O-]Cl,,test
US20040102450A1,CC1CN(Cc2ccc(C#N)c(NC(c3ccccc3)c3ccccc3)c2)C(=O)[C@H](C)N1C(=O)OCc1ccccc1>>CC1CNC(=O)C(C)N1C(=O)OCc1ccccc1,,CCOC(C)=O,,Cl,,test
US20040209897A1,CCOC(=O)C(C#N)c1ccccc1>>CCOC(=O)C(CN)c1ccccc1,,CCO,,Cl,,test
US20130053375A1,Clc1ccnc2ccc(I)cc12.SC1CCOCC1>>Clc1ccnc2ccc(SC3CCOCC3)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US05686458,COc1cccc2c(N3CCc4ccccc4C3C(F)(F)F)nc(Cl)nc12.Cc1cc(F)ccc1N>>COc1cccc2c(N3CCc4ccccc4C3C(F)(F)F)nc(Nc3ccc(F)cc3C)nc12.Cl,,CN(C)C=O,,,,test
US05807868,COc1ccc(CCN)cc1C.O=C(Cl)C1CCC1>>COc1ccc(CCNC(=O)C2CCC2)cc1C,,C1CCOC1,O,CCN(CC)CC,Cl,test
US05464857,CC(C)(NO)C(C)(C)NO.O=Cc1ccc(C(=O)O)cc1>>CC1(C)N(O)C(c2ccc(C(=O)O)cc2)N(O)C1(C)C,,O,,O=S(=O)(O)O,,test
US20090018122A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(N)CNc1c([N+](=O)[O-])cnc2ccc(OCc3ccccc3)cc12>>CC(C)(CNc1c([N+](=O)[O-])cnc2ccc(OCc3ccccc3)cc12)NC(=O)OC(C)(C)C,,C1CCOC1,,[Na+].[OH-],,test
US06320078B1,CCOC(=O)COc1ccc(C(=O)OCC)cc1.NCc1cccnc1>>CCOC(=O)c1ccc(OCC(=O)NCc2cccnc2)cc1,,CCO,,C1CCC2=NCCCN2CC1,,test
US04504490,COC(=O)N=C(NC(=O)OC)SC.NC(=O)Nc1ccc(S(=O)(=O)Oc2ccccc2)cc1N>>COC(=O)NC(=Nc1cc(S(=O)(=O)Oc2ccccc2)ccc1NC(N)=O)NC(=O)OC,,CCOC(C)=O,CO,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040204584A1,COc1ccc(C2COCCO2)c2sc(N)nc12.COc1cccc(C(=O)O)n1>>COc1cccc(C(=O)Nc2nc3c(OC)ccc(C4COCCO4)c3s2)n1,,C1CCOC1,ClC(Cl)Cl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120053206A1,CCOC(=O)c1c(C)c2ccc(C(F)(F)F)cc2n(C2CCOCC2)c1=O>>Cc1c(C(=O)O)c(=O)n(C2CCOCC2)c2cc(C(F)(F)F)ccc12,,CCO,O,[Na+].[OH-],,test
US20150299220A1,C[C@@H]1CCCN1.O=C(O)c1cnc(C2CC2)c(OCC2CC2)n1>>C[C@@H]1CCCN1C(=O)c1cnc(C2CC2)c(OCC2CC2)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20050020459A1,CC(=O)OC(C)=O.NC(=O)COc1cccc(C(O)C(c2ccccc2)C2SCCCS2)c1>>CC(=O)OC(c1cccc(OCC(N)=O)c1)C(c1ccccc1)C1SCCCS1,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20090191177A1,CC(=O)c1cc(C)cn2c(=O)cc(N3CCOCC3)nc12>>Cc1cc(C(C)O)c2nc(N3CCOCC3)cc(=O)n2c1,,CO,,O,[BH4-].[Na+],test
US20070142413A1,N#CCC(=O)C(F)(F)F.NN>>Nc1cc(C(F)(F)F)n[nH]1,,CCO,,O,,test
US20100190745A1,CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(B2OC(C)(C)C(C)(C)O2)cn1.CCOC(=O)c1cn(CC2CCNC2)c2ccc(I)cc2c1=O>>CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2ccc3c(c2)c(=O)c(C(=O)OCC)cn3CC2CCNC2)cn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,Cl,O=C([O-])O.[Na+],test
US04029679,CC(=O)OC(C)=O.CCOP(=O)(CCCN)OCC>>CCOP(=O)(CCCNC(C)=O)OCC,,c1ccncc1,,,,test
US08916599B2,CCOC(=O)c1cc(NC(=S)Nc2c(Cl)cccc2Cl)c(NC)cc1F>>Cn1c(Nc2c(Cl)cccc2Cl)nc2cc(C(=O)O)c(F)cc21,,CC#N,,CC(C)N=C=NC(C)C,,test
US20140088306A1,CC(C)(C)[Si](C)(C)OCCBr.O=[N+]([O-])c1ccc(-c2cnc3ccc(O)cc3n2)cc1>>CC(C)(C)[Si](C)(C)OCCOc1ccc2ncc(-c3ccc([N+](=O)[O-])cc3)nc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080051395A1,O=C(CBr)c1c(-c2cccc(Br)c2)nn2cc(C(F)(F)F)ccc12.[F-]>>O=C(CF)c1c(-c2cccc(Br)c2)nn2cc(C(F)(F)F)ccc12,,CC(=O)N(C)C,,O,,test
US07312225B2,O=C(NCCCCNc1nc(Cl)ncc1Br)c1cccc([N+](=O)[O-])c1>>Nc1cccc(C(=O)NCCCCNc2nc(Cl)ncc2Br)c1,,C1CCOC1,Cl,CCOC(C)=O,[Na+].[OH-],test
US06002008,N#Cc1cnc2ccc([N+](=O)[O-])cc2c1Cl.Nc1ccc(F)c(Br)c1>>N#Cc1cnc2ccc([N+](=O)[O-])cc2c1Nc1ccc(F)c(Br)c1,,CCO,,,,test
US20040014962A1,CC(C)C[C@H](N)CO.O=C(Cl)OCc1ccccc1>>CC(C)C[C@@H](CO)NC(=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20050054819A1,CCCC[C@H](NC(=O)OCc1ccccc1)C(OC(=O)c1ccccc1)C(=O)N[C@H](C)c1ccccc1>>CCCC[C@H](N)C(O)C(=O)N[C@H](C)c1ccccc1,,C1COCCO1,O,[Na+].[OH-],,test
US20050153970A1,CCN(CCCc1ccc(F)cc1)C[C@H](O)[C@@H](C)N.Cn1nnnc1-c1cccc(NC(=O)Oc2ccccc2)c1>>CCN(CCCc1ccc(F)cc1)C[C@H](O)[C@@H](C)NC(=O)Nc1cccc(-c2nnnn2C)c1,,CC#N,,,,test
US04609670,Cc1ccc(C(=O)CBr)cc1.Cn1ccnc1>>Cc1ccc(C(=O)CN2C=C[NH+](C)C2)cc1.[Br-],,CCOCC,,,,test
US04320125,CCCCN.N#CC(C(=O)c1ccccc1Cl)=C1NC(c2ccccc2)=CS1>>CCCC[NH3+].N#CC(=C([O-])c1ccccc1Cl)c1nc(-c2ccccc2)cs1,,C1COCCO1,,,,test
US20050256172A1,CCCI.NCCc1ccccc1>>CCCNCCc1ccccc1,,C1CCOC1,,CCN(CC)CC,,test
US20050261291A1,CCC=O.Cc1cccc(N2CCNCC2)c1C1=CC(C)(C)CC(C)(C)C1>>CCCN1CCN(c2cccc(C)c2C2=CC(C)(C)CC(C)(C)C2)CC1,,C1CCOC1,CCOC(C)=O,O=C([O-])O.[Na+],,test
US20100048606A1,CCCC[Sn](CCCC)(CCCC)c1cncc(C(=O)OC)c1.COCOCc1cc(Cl)nc(OC)c1>>COCOCc1cc(OC)nc(-c2cncc(C(=O)OC)c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US20150266837A1,CCN(NC(=O)OC(C)(C)C)C(=O)Nc1nnn[nH]1>>CCN(N)C(=O)Nc1nnn[nH]1,,CCOC(C)=O,Cl,,,test
US20120214803A1,Nc1cc(C(F)(F)F)ccc1S(=O)(=O)Nc1cccc2cccnc12>>O=S1(=O)Nc2c(ccc3cccnc23)-c2cc(C(F)(F)F)ccc21,,C1CCOC1,CC(=O)O,CC(C)(C)ON=O,,test
US20100210452A1,CCOC(=O)/C=C/C=O.COc1ccc(/C=C/C=NS(=O)(=O)c2ccc(OC)cc2)cc1>>CCOC(=O)C[C@@H]1C(=O)N(S(=O)(=O)c2ccc(OC)cc2)C=C[C@@H]1c1ccc(OC)cc1,,ClC(Cl)Cl,,,,test
US20120065231A1,CCCNCC1CC1.N#Cc1cc(Br)sc1Br>>CCCN(CC1CC1)c1cc(C#N)c(Br)s1,,O,,CCN(CC)CC,,test
US20070066583A1,COc1cc(N2CCN(C(=O)Cn3c(=O)oc4cc(C#N)ccc43)CC2)ccc1Cl.NO>>COc1cc(N2CCN(C(=O)Cn3c(=O)oc4cc(C(=N)NO)ccc43)CC2)ccc1Cl,,CCO,,Cl,,test
US20090270394A1,CC(C)(C)OC(=O)NC1(C(=O)NCc2ccccc2)CCCCC1>>NC1(C(=O)NCc2ccccc2)CCCCC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20030065193A1,COC(=O)[C@@H](N)Cc1ccc2ccccc2c1.Cc1ccc(S(=O)(=O)N2CCC[C@H]2C(=O)O)cc1>>Cc1ccc(S(=O)(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)O)cc1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20090203676A1,CC(C)(C)OC(=O)N1CCC(CC=O)CC1.C[C@H]1CN(c2ccc(S(C)(=O)=O)cc2)CCN1>>C[C@H]1CN(c2ccc(S(C)(=O)=O)cc2)CCN1CCC1CCN(C(=O)OC(C)(C)C)CC1,,CO,,[BH4-].[Na+],,test
US20100331295A1,CC(C)(N=[N+]=[N-])c1cc(-c2ccc(-c3cccc(S(C)(=O)=O)c3)s2)n(-c2ccccc2Cl)n1>>CC(C)(N)c1cc(-c2ccc(-c3cccc(S(C)(=O)=O)c3)s2)n(-c2ccccc2Cl)n1,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060094767A1,CC(C)(C)OC(=O)NN1CCN(CC2(C)Cn3cc([N+](=O)[O-])nc3O2)CC1.O=Cc1ccc(OC(F)(F)F)cc1>>CC1(CN2CCN(N=Cc3ccc(OC(F)(F)F)cc3)CC2)Cn2cc([N+](=O)[O-])nc2O1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20150225412A1,CC(C)(C)CN.N#CCC(=O)N1CCC[C@@H]1Cn1c(NC(=O)c2ccc(C(F)F)s2)nc2cc(C=O)ccc21>>CC(C)(C)CNCc1ccc2c(c1)nc(NC(=O)c1ccc(C(F)F)s1)n2C[C@H]1CCCN1C(=O)CC#N,,ClCCl,,[BH3-]C#N.[Na+],,test
US20160158207A1,COC(=O)c1cccc(Nc2n[nH]c3c2CN(C(=O)OC(C)(C)C)CC3)c1.Cl>>COC(=O)c1cccc(Nc2n[nH]c3c2CNCC3)c1.Cl,,CCOC(C)=O,,,,test
US20080280925A1,CN(CC=O)C(=O)OC(C)(C)C.COc1ccccc1CCOc1cc(C(F)(F)F)nn1-c1cccc(C#N)c1>>COc1ccccc1CCOc1cc(C(F)(F)F)nn1-c1cccc(CNCCN(C)C(=O)OC(C)(C)C)c1,,C1CCOC1,CO,CC(=O)O,[BH3-]C#N.[Na+],test
US20160009704A1,CC(C)(C)OC(=O)c1cn(CCC(F)Cn2cc(N)nn2)nn1.O=C(O)Cc1ccccn1>>CC(C)(C)OC(=O)c1cn(CCC(F)Cn2cc(NC(=O)Cc3ccccn3)nn2)nn1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100105744A1,Cc1cc(F)ccc1[N+](=O)[O-].O=C1CCC(=O)N1Br>>O=[N+]([O-])c1ccc(F)cc1CBr,,ClC(Cl)Cl,,,,test
US05378849,CC(=O)N1Cc2c(ccc(O)c2O)[C@@H](c2ccc(O)c(O)c2)C1.CCO.Cl>>Cl.O.Oc1ccc([C@H]2CNCc3c2ccc(O)c3O)cc1O,,CCO,,,,test
US20060235030A1,CN1CCC(N)CC1.Cc1ccc(C(=O)NC(C)C)cc1-c1nc(S(C)=O)nc2c1CNC(=O)N2c1c(F)cccc1F>>Cc1ccc(C(=O)NC(C)C)cc1-c1nc(NC2CCN(C)CC2)nc2c1CNC(=O)N2c1c(F)cccc1F,,C1CCOC1,,,,test
US20050038068A1,C=C[Sn](CCCC)(CCCC)CCCC.COCC#Cc1sc(-c2csc3[nH]c(=O)c(C#N)c(O)c23)cc1Br>>C=Cc1cc(-c2csc3[nH]c(=O)c(C#N)c(O)c23)sc1C#CCOC,,CN(C)C=O,,COCCOC,,test
US20130345419A1,CC1(C)CC(C)(C)CC(O)(C(F)(F)C(=O)N2CCC[C@H]2c2cc(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)on2)C1>>CC1(C)CC(C)(C)CC(O)(C(F)(F)C(=O)N2CCC[C@H]2c2cc(CO)on2)C1,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05885985,CCCC(=O)Nc1cccc(N)c1.Cl.N#CN1CCCC1>>CCCC(=O)Nc1cccc(NC(=N)N2CCCC2)c1.Cl,CN(C)c1ccncc1,Clc1ccccc1,,,,test
US06982259B2,COc1ccc(C=O)c2ccccc12.c1cn(-c2ccc(OC3CCCNC3)cc2)cn1>>COc1ccc(CN2CCCCC2)c2ccccc12,,ClCCl,,CO,,test
US20120329785A1,CN1CCN(C(=O)c2ccc(N)cc2)CC1.COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1>>COc1ccc2nc(Nc3ccc(C(=O)N4CCN(C)CC4)cc3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US05051515,Cc1cc(CCCCCCCBr)on1.Cn1nnnc1S>>Cc1cc(CCCCCCCSc2nnnn2C)on1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130184429A1,COC(=O)C(Br)COC(C)=O.[I-]>>COC(=O)C(I)COC(C)=O,,CC(C)=O,,O,,test
US20080064740A1,COc1cc(OCCF)ccc1CNC(=O)OC(C)(C)C.Cl>>COc1cc(OCCF)ccc1CN.Cl,,CC(=O)O,,,,test
US20090239918A1,NC(Cc1ccccc1)c1ccccc1.O=C=NCCCl>>O=C(NCCCl)NC(Cc1ccccc1)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20080004267A1,N[C@@H](Cc1ccc([N+](=O)[O-])cc1)c1csc(-c2cccs2)n1.O=C=NCc1ccccc1>>O=C(NCc1ccccc1)N[C@@H](Cc1ccc([N+](=O)[O-])cc1)c1csc(-c2cccs2)n1,,ClCCl,,Br,CCN(CC)CC,test
US20100120739A1,NNc1ccc(Cl)nn1.O=C(O)Cc1ccc2ncccc2c1>>Clc1ccc2nnc(Cc3ccc4ncccc4c3)n2n1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20090227539A1,CC(C)(C)OC(=O)N(CCCC12BBBBBBBC(BB1)B2)C(=O)OC(C)(C)C>>NCCCC12BBBBBBBC(BB1)B2,,CCOC(C)=O,Cl,,,test
US20130303533A1,CCn1ccc2c(Cl)nc(S(=O)(=O)c3ccc(F)cc3)nc21.Nc1cc[nH]n1>>CCn1ccc2c(Nc3cc[nH]n3)nc(S(=O)(=O)c3ccc(F)cc3)nc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20150183797A1,C=O.COc1ccc(CC(=O)c2ccc3c(c2OC)C=CC(C)(C)O3)cc1OC>>C=C(C(=O)c1ccc2c(c1OC)C=CC(C)(C)O2)c1ccc(OC)c(OC)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030073688A1,CCOC(=O)CC(Sc1ccc2c(c1)OCC(=O)N2CCCN(C(=O)OCc1ccccc1)c1cccc[n+]1[O-])c1ccccc1>>CCOC(=O)CC(Sc1ccc2c(c1)OCC(=O)N2CCCN(C(=O)OCc1ccccc1)c1ccccn1)c1ccccc1,Cl[Ti](Cl)(Cl)Cl,C1CCOC1,,,,test
US20080221322A1,C1CC[N+]2(C1)CCC2.F[P-](F)(F)(F)(F)F>>C1CC[N+]2(C1)CCC2.F[P-](F)(F)(F)(F)F,,O,,[Cl-].[Na+],,test
US20060247210A1,CN.Nc1[nH]nc(CCCBr)c1-c1nc2ccccc2s1>>CNCCCc1n[nH]c(N)c1-c1nc2ccccc2s1,,C1CCOC1,,,,test
US20040067955A1,CCI.Nc1nc(-c2ccccc2)c(-c2ccc(=O)[nH]n2)cc1Cl>>CCn1nc(-c2cc(Cl)c(N)nc2-c2ccccc2)ccc1=O,,CN(C)C=O,,O,[H-].[Na+],test
US20050176679A1,C#C[C@]1(O)CC[C@H]2[C@H]3[C@H](CC[C@@]21C)C1=C(CC(=O)CC1)C[C@H]3C.OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)OC(O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O>>C#C[C@]1(O)CC[C@H]2[C@H]3[C@H](CC[C@@]21C)C1=C(CC(=O)CC1)C[C@H]3C.OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)OC(O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O,,CC(C)O,,,,test
US20110212937A1,C=C[Sn](CCCC)(CCCC)CCCC.CNc1nc(Cl)nc(C(=O)N(C)OC)c1Br>>C=Cc1c(NC)nc(Cl)nc1C(=O)N(C)OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20120010228A1,CS(=O)(=O)Nc1cccc(CN2CN(c3ccccc3)C3(CCNCC3)C2=O)c1.O=C1Cc2ccccc2N1CCCCl>>CS(=O)(=O)Nc1cccc(CN2CN(c3ccccc3)C3(CCN(CCCN4C(=O)Cc5ccccc54)CC3)C2=O)c1,,CCC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20070111992A1,N#Cc1nc(NCCO)cc(-c2cccc(C(F)(F)F)c2)n1>>N#Cc1nc(NCC=O)cc(-c2cccc(C(F)(F)F)c2)n1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20120022057A1,CC(C)(C)OC(=O)N1CCc2c(cccc2C(=O)O)C1.Nc1ccccc1>>CC(C)(C)OC(=O)N1CCc2c(cccc2C(=O)Nc2ccccc2)C1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160214943A1,C=C(C)B1OC(C)(C)C(C)(C)O1.CCOC(=O)Cn1nc(OS(=O)(=O)C(F)(F)F)cc1-c1ccc(-c2cccc(S(C)(=O)=O)c2)cc1>>C=C(C)c1cc(-c2ccc(-c3cccc(S(C)(=O)=O)c3)cc2)n(CC(=O)OCC)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20070037802A1,C1COCCN1.Cc1ccc(S(=O)(=O)OCCOc2ccc3[nH]nc(S(=O)(=O)c4ccccc4)c3c2)cc1>>O=S(=O)(c1ccccc1)c1n[nH]c2ccc(OCCN3CCOCC3)cc12,,C1CCOC1,,,,test
US20130102576A1,COC(=O)CBr.O=c1[nH]c2ccc([N+](=O)[O-])cc2o1>>COC(=O)Cn1c(=O)oc2cc([N+](=O)[O-])ccc21,,CN(C)C=O,,[H-].[Na+],,test
US07368437B1,C1CCOC1.CCCCON=O.Nc1ncnc2c([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)[nH]nc12>>CC(=O)OC[C@H]1O[C@@H](c2n[nH]c3cncnc23)[C@H](OC(C)=O)[C@@H]1OC(C)=O,,C1CCOC1,,,,test
US20160015712A1,O=C(O)CCOc1ccc(-n2nnc3cnc(NCCCn4cc([N+](=O)[O-])cn4)nc32)cc1>>Nc1cnn(CCCNc2ncc3nnn(-c4ccc(OCCC(=O)O)cc4)c3n2)c1,[Pd],C1CCOC1,,,,test
US20050153959A1,COCn1cc2cc(CC(OC(=O)N3CCC(c4cc5ccccc5[nH]c4=O)CC3)c3nccn3Cc3cc(F)cc(F)c3)cc(C)c2n1>>Cc1cc(C[C@@H](OC(=O)N2CCC(c3cc4ccccc4[nH]c3=O)CC2)c2nccn2Cc2cc(F)cc(F)c2)cc2cn[nH]c12,,CO,,CC(=O)Cl,,test
US20140275656A1,CC/C=C/C=C\CC/C=C\CCCCCC(OCC)OCC>>CC/C=C/C=C\CC/C=C\CCCCCC=O,,Cc1ccccc1,,Cl,,test
US20090036492A1,CCCOc1cc(OC)c(C(=O)OCc2ccccc2)c2c1[C@]1(C)C(=O)C(C(C)=O)=C(O)C=C1O2>>CCCOc1cc(OC)c(C(=O)O)c2c1[C@]1(C)C(=O)C(C(C)=O)=C(O)C=C1O2,[Pd],CCOC(C)=O,,[H][H],,test
US20040106653A1,COCOc1cccc(S(=O)(=O)c2ccc(C[C@@H](C)N(C[C@H](O)c3cccc(Cl)c3)C(=O)OC(C)(C)C)cc2)c1C(=O)O.Cl>>C[C@H](Cc1ccc(S(=O)(=O)c2cccc(O)c2C(=O)O)cc1)NC[C@H](O)c1cccc(Cl)c1.Cl,,C1COCCO1,,,,test
US20080194577A1,CN1CCNCC1.Nc1nc(Cl)cc(C2CCCC2)n1>>CN1CCN(c2cc(C3CCCC3)nc(N)n2)CC1,,CCO,,,,test
US20090156571A1,CN(C)CCN(C)C(=O)c1ccc(-c2cc(Cl)c(CC3CCN(C4CCCCC4)C3=O)c(Cl)c2)cc1.O=C(OO)c1cccc(Cl)c1>>CN(C)CC[NH+]([O-])C(=O)c1ccc(-c2cc(Cl)c(CC3CCN(C4CCCCC4)C3=O)c(Cl)c2)cc1,,ClCCl,,,,test
US20110224208A1,COCCN1C(=O)c2ccccc2C(C(=O)Nc2ccc(C(=O)OC)cc2)C1c1cccs1>>COCCN1C(=O)c2ccccc2C(C(=O)Nc2ccc(C(=O)O)cc2)C1c1cccs1,,CO,,[Na+].[OH-],,test
US20080176872A1,Cc1nc(N[C@@H](CO)c2ccc(F)cc2)nc(Nc2cc(C3CC3)[nH]n2)c1N.N=CN>>Cc1nc(N[C@@H](CO)c2ccc(F)cc2)nc2c1ncn2-c1cc(C2CC2)[nH]n1,,CCO,,CC(=O)O,,test
US20110021568A1,C=O.CCOC(=O)c1csc([C@H](O)C[C@@H](N[S@@](=O)C(C)(C)C)C(C)C)n1>>CCOC(=O)c1csc([C@H]2CC(C(C)C)N(S(=O)C(C)(C)C)CO2)n1,,Cc1ccccc1,,,,test
US20150307531A1,COc1cccc(-n2c3ccccc3c3ccccc32)c1.ClP(c1ccccc1)c1ccccc1>>COc1cccc(-n2c3ccccc3c3ccccc32)c1P(c1ccccc1)c1ccccc1,,Cc1ccccc1,,,,test
US06107495,CCCBr.COC(=O)CCCC(=O)Cl>>CCCC(=O)CCCC(=O)OC,,C1CCOC1,,[Mg],[Cl-].[NH4+],test
US09212190B2,N#CC[C@H]1CCc2sc3ncnc(NC4CCC(N5CCOCC5)CC4)c3c21.OO>>NC(=O)C[C@H]1CCc2sc3ncnc(NC4CCC(N5CCOCC5)CC4)c3c21,,CO,ClCCl,,,test
US20150094297A1,CCN(CC)S(F)(F)F.COc1cc(OCc2csc(C3(O)CCC(F)(F)CC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1>>COc1cc(OCc2csc(C3(F)CCC(F)(F)CC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1,,ClCCl,,,,test
US20130317045A1,NC(=O)c1ccsc1N.O=C(O)C(F)(F)c1ccc(F)cc1>>NC(=O)c1ccsc1NC(=O)C(F)(F)c1ccc(F)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070167449A1,BrBr.COc1ccc(Nc2nccs2)cc1>>COc1ccc(Nc2ncc(Br)s2)cc1,,CN(C)C=O,,,,test
US20110172245A1,Cn1c(NC(=O)C2CC2)nc2ccc(Oc3cccc(NC(=O)OC(C)(C)C)c3)cc21>>Cn1c(NC(=O)C2CC2)nc2ccc(Oc3cccc(N)c3)cc21,,O=C(O)C(F)(F)F,,,,test
US20050137226A1,Cl.Ic1ccc(NC2CN3CCC2CC3)cc1>>Cl.Ic1ccc(NC2CN3CCC2CC3)cc1,,C1COCCO1,CCOC(C)=O,,,test
US20070287697A1,CN.O=C(N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(CC(F)(F)F)C1=S)N1CCC(n2c(=O)[nH]c3ncccc32)CC1>>CN=C1[C@H](NC(=O)N2CCC(n3c(=O)[nH]c4ncccc43)CC2)CC[C@@H](c2cccc(F)c2F)CN1CC(F)(F)F,Cl[Hg]Cl,CCO,,,,test
US07223759B2,COc1ccc(CN2C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H](O)C2)cc1>>CC(C)(C)[Si](C)(C)O[C@H]1CNC[C@H](O)C1,[Pd],CO,,[H][H],,test
US20160159809A1,Clc1nc(NCC(c2ccccc2)c2ccccc2)c2ccccc2n1.c1ccc2c(c1)CCNC2>>c1ccc(C(CNc2nc(N3CCc4ccccc4C3)nc3ccccc23)c2ccccc2)cc1,,CCO,,CO,ClC(Cl)Cl,test
US04016209,CNCCC[N+](C)(C)C.ClCCCBr.[Br-]>>Br.CN(CCCCl)CCC[N+](C)(C)C.[Br-],,CC#N,,,,test
US04777279,CC(C)COP(C)(=O)CCCl.COC1=N[C@H](C(C)C)C(OC)=NC1.[Li]CCCC>>CCCCOC[P+]([O-])=CC[C@@H]1N=C(OC)[C@@H](C(C)C)N=C1OC,,CCCCCC,,C1CCOC1,,test
US04180669,CCCCCC(C)C(C)c1cc(O)c(C2=CCN(Cc3ccccc3)CC2)c(OC)c1.Cl>>CCCCCC(C)C(C)c1cc(O)c(C2C=CNCC2)c(OC)c1.Cl,[Pd],COCCO,,,,test
US20130338367A1,CC(C)(C)OC(=O)Nc1cn(-c2cccnc2)nc1Cl.CI>>CN(C(=O)OC(C)(C)C)c1cn(-c2cccnc2)nc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20160000760A1,CC(C)(C)OC(=O)N1CCCC(Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)C1.Nc1cc(Cl)c(Br)c(C(F)(F)F)c1>>CC(C)(C)OC(=O)N1CCCC(Oc2ccc(-c3c(Cl)cc(N)cc3C(F)(F)F)cc2)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20020028823A1,CC(=O)OC(C)CCCCn1c(=O)c2c(ncn2C)n(CCCCCCNC(=O)CCCC[C@H]2SC[C@@H]3NC(=O)N[C@@H]32)c1=O>>C[C@@H](O)CCCCn1c(=O)c2c(ncn2C)n(CCCCCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@@H]32)c1=O,Cl,CO,,N,,test
US20020082452A1,COc1cc(CO)ccc1O.Fc1ccc(OCCBr)cc1.[C-]#N>>COc1cc(CC#N)ccc1OCCOc1ccc(F)cc1,,CN(C)C=O,,O,,test
US04916152,COC(=O)CCC/C=C\[C@@H]1C[C@@H](NS(=O)(=O)c2ccc(Cl)cc2)CN1S(=O)(=O)c1ccc(Cl)cc1>>O=S(=O)(N[C@@H]1C[C@@H](/C=C\CCCCO)N(S(=O)(=O)c2ccc(Cl)cc2)C1)c1ccc(Cl)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070060569A1,BrCc1ccccc1.CCOc1ccc(-c2ccc(S(=O)(=O)N[C@@H](C(=O)O)C3CCN(C(=O)OC(C)(C)C)CC3)s2)cc1>>CCOc1ccc(-c2ccc(S(=O)(=O)N[C@@H](C(=O)OCc3ccccc3)C3CCN(C(=O)OC(C)(C)C)CC3)s2)cc1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060205718A1,CC(=O)Cl.CCOc1cc(CN2CCC(Nc3nc4cc(N)ccc4o3)CC2)ccc1OC>>CCOc1cc(CN2CCC(Nc3nc4cc(NC(C)=O)ccc4o3)CC2)ccc1OC,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20050158863A1,CCCCCCN1C=CN(C)C1.O=C(O)c1cc(O)ccc1O>>CCCCCCN1C=CN(C)C1.O=C(O)c1cc(O)ccc1O,,CCO,,,,test
US20050131017A1,CC(C)(S)[C@H](N)C(=O)O.CI.COC(=O)Cl>>COC(=O)N[C@H](C(=O)O)C(C)(C)SC,,CO,,[Na+].[OH-],,test
US20120059028A1,COC(=O)CCC(C)=O.Nc1sc2c(c1C(=O)c1cc3ccccc3o1)CCCC2>>COC(=O)Cc1c(C)nc2sc3c(c2c1-c1cc2ccccc2o1)CCCC3,,CN(C)C=O,,C[Si](C)(C)Cl,,test
US20100292455A1,COc1ccc(C(OC(c2ccccc2)C2CN(C(=O)CCCCCNC(=O)OC3CCC4(C)C(=CCC5C4CCC4(C)C(C(C)CCCC(C)C)CCC54)C3)CC2O)c2ccc(OC)cc2)cc1.O=C1CCC(=O)O1>>COc1ccc(C(OC(c2ccccc2)C2CN(C(=O)CCCCCNC(=O)OC3CCC4(C)C(=CCC5C4CCC4(C)C(C(C)CCCC(C)C)CCC54)C3)CC2OC(=O)CCC(=O)O)c2ccc(OC)cc2)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20110263647A1,COC(=O)[C@H](Cc1ccc2c(c1)OCCO2)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@H](CO)Cc1ccc2c(c1)OCCO2,,C1CCOC1,CCO,Cl,[BH4-].[Li+],test
US03987047,CCOC(=O)Cl.COc1c2c(nc3ccccc13)CCN(Cc1ccccc1)CC2>>CCOC(=O)N1CCc2nc3ccccc3c(OC)c2CC1,,ClC(Cl)Cl,,,,test
US05219868,ClCc1ccc(Cl)nc1.O=[N+]([O-])N=C1NCCN1C=Nc1ccc(F)cc1>>O=[N+]([O-])N=C1N(C=Nc2ccc(F)cc2)CCN1Cc1ccc(Cl)nc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040110767A1,Cc1ccc(S(=O)(=O)Oc2ccc(C=O)cc2)cc1.Nc1ccc(OCCN2CCCC2)cc1>>Cc1ccc(S(=O)(=O)Oc2ccc(CNc3ccc(OCCN4CCCC4)cc3)cc2)cc1,,CCO,CO,[BH4-].[Na+],,test
US05710275,CC(C)(C)C(=O)Cl.C[C@H]1CC2N(C)C(=O)CC[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@H]3O)[C@H]12>>C[C@H]1CC2N(C)C(=O)CC[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@H]3OC(=O)C(C)(C)C)[C@H]12,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,c1ccncc1,,test
US04266014,CCOC(=O)CC(=O)C(=O)OCC.NNCC(F)(F)F>>CCOC(=O)C1=NN(CC(F)(F)F)C(=O)C1,,CC(=O)O,,O,[Na],test
US05155113,O=C(Br)c1ccccc1.O=c1[nH]c(=O)n([C@H]2C[C@H](OCc3ccccc3)[C@@H](CO)O2)cc1F>>O=C(c1ccccc1)n1c(=O)c(F)cn([C@H]2C[C@H](OCc3ccccc3)[C@@H](CO)O2)c1=O,,C1COCCO1,,CCN(CC)CC,C[Si](C)(C)Cl,test
US20100036150A1,COC(=O)C(O)c1ccc(O)cc1.Clc1ccc(CBr)cc1Cl>>COC(=O)C(O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120302756A1,CC(C)(C)[S@](=O)/N=C(\CCCCCl)c1ccccc1>>CC(C)(C)[S@](=O)N1CCCC[C@@H]1c1ccccc1,,CO,,,,test
US20140135320A1,COCCOCOc1ccc(-c2cccc(F)c2)cc1-c1ccc(C(F)(F)F)nc1>>Oc1ccc(-c2cccc(F)c2)cc1-c1ccc(C(F)(F)F)nc1,,CO,Cl,,,test
US20040077669A1,CCC#CCO.Fc1ccccc1-c1cc(Cl)ncn1>>CCC#CCOc1cc(-c2ccccc2F)ncn1,,CN(C)C=O,,O,[H-].[Na+],test
US20130116216A1,O=[N+]([O-])c1ccc(S(=O)(=O)NCCN2CCOCC2)cc1>>Nc1ccc(S(=O)(=O)NCCN2CCOCC2)cc1,[Fe],O,,CCO,[Cl-].[NH4+],test
US20090005356A1,OCc1ccccc1-c1c[nH]c2ncc(Br)c(Cl)c12>>Brc1cnc2[nH]cc3c2c1OCc1ccccc1-3,,CN(C)C=O,,[H-].[Na+],,test
US20060111375A1,COc1cc2c(Oc3cc(C)c(C)nc3-c3ccc(C)cn3)ccnc2cc1OCCCl.NCCO>>COc1cc2c(Oc3cc(C)c(C)nc3-c3ccc(C)cn3)ccnc2cc1OCCNCCO,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04588732,C=C(Cc1ccc(-c2cccc3cncn23)cc1)C(=O)OC>>C=C(Cc1ccc(-c2cccc3cncn23)cc1)C(=O)O,,O,,CO,C[O-].[Na+],test
US20020035113A1,O=C(O)Cc1coc2ccc(F)cc12>>OCCc1coc2ccc(F)cc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090324581A1,COC(=O)c1ccc(C(F)(F)F)c(OS(=O)(=O)C(F)(F)F)c1.OB(O)OC1=CCCC1>>COC(=O)c1ccc(C(F)(F)F)c(C2=CCCC2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150111891A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2cc(Cl)ccc2c1OS(=O)(=O)C(F)(F)F>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2cc(Cl)ccc2c1O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080039452A1,CC(C)(C)C(=O)OCCl.O=Cc1c[nH]cn1>>CC(C)(C)C(=O)OCn1cnc(C=O)c1,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20140094462A1,C=CC[C@@H](C)C(=O)O.C=CC[C@H](C)C(=O)N[C@@H](CO)c1ccccn1>>C=CC[C@H](C)C(=O)N[C@@H](COC(=O)[C@H](C)CC=C)c1ccccn1,,ClCCl,,CCCCCC,CCOC(C)=O,test
US20160120841A1,COc1ccc(C(=O)CC(=O)C2CCCO2)c(O)c1>>COc1ccc2c(=O)cc(C3CCCO3)oc2c1,Cl[Fe](Cl)Cl,ClCCl,,,,test
US20070219186A1,O=C(Nc1cccc(-c2ccnc3cc(-c4ccncc4)nn23)c1)c1cc([N+](=O)[O-])cc(C(F)(F)F)c1>>Nc1cc(C(=O)Nc2cccc(-c3ccnc4cc(-c5ccncc5)nn34)c2)cc(C(F)(F)F)c1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20160211456A1,BrC1=C2C=c3cc4c5ccccc5c5ccccc5c4cc3=C2C2(C=C1)c1ccccc1-c1ccccc12.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(C2=C3C=c4cc5c6ccccc6c6ccccc6c5cc4=C3C3(C=C2)c2ccccc2-c2ccccc23)OC1(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,CC(=O)[O-].[K+],,test
US20120077806A1,CCCC(N)c1ccc(OCOC)cc1.N#CCC(=O)O>>CCCC(NC(=O)CC#N)c1ccc(OCOC)cc1,CN(C)C=O,C1CCOC1,C1CCOC1,O=C(Cl)C(=O)Cl,O=C([O-])O.[Na+],test
US20020016322A1,CC(C)(S)CN1CCC2(CC1)OCCO2>>CC(C)(S)CN1CCC(=O)CC1,,C1CCOC1,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20090181941A1,CO.O=C(O)Cc1cccc(-c2cncc(Br)c2)c1>>COC(=O)Cc1cccc(-c2cncc(Br)c2)c1,,C1CCOC1,,O=S(Cl)Cl,O=C([O-])O.[Na+],test
US20100029619A1,CC(C)(C#N)c1ccc(C(=O)Nc2cn3cc(Cl)ccc3n2)cc1>>CC(C)(CN)c1ccc(C(=O)Nc2cn3cc(Cl)ccc3n2)cc1,,N,,CO,,test
US05624600,CCCCCC(=O)O.O=C1O[C@H](c2ccccc2)CN1c1ccc(O)cc1>>CCCCCC(=O)Oc1ccc(N2C[C@@H](c3ccccc3)OC2=O)cc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20110009454A1,CCOCCBr.Nc1ncccc1C(=O)NCc1ccc(O)cc1>>CCOCCOc1ccc(CNC(=O)c2cccnc2N)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20070185155A1,BrCCCBr.OC(c1ccccc1)(c1ccccc1)C12CCN(CC1)CC2>>OC(c1ccccc1)(c1ccccc1)C12CC[N+](CCCBr)(CC1)CC2.[Br-],,CC#N,,,,test
US20140288094A1,C=CC(=O)OCC.Cc1c(-c2cccnc2)n[nH]c1N>>Cc1c(-c2cccnc2)nn2c1NC(=O)CC2,,O,c1ccncc1,,,test
US06903087B2,COC(=O)c1cc(Cl)c(I)cc1OC>>COc1cc(I)c(Cl)cc1C(=O)O,,CO,,[Na+].[OH-],,test
US04886817,C(=C/c1ccccc1)\CNCCNc1cccnc1.S=C(Cl)Cl>>S=C1N(C/C=C/c2ccccc2)CCN1c1cccnc1,,C1CCOC1,,CCN(CC)CC,,test
US20110046369A1,CCCCOc1nc(N)c2nc(OC)n(CCCO)c2n1.CS(=O)(=O)Cl>>CCCCOc1nc(N)c2nc(OC)n(CCCOS(C)(=O)=O)c2n1,,CN1CCCC1=O,,CCN(CC)CC,O,test
US20120309757A1,COC(=O)c1ccc2c(ccn2Cc2ccc(Br)cc2)c1>>O=C(O)c1ccc2c(ccn2Cc2ccc(Br)cc2)c1,,CO,,[Na+].[OH-],,test
US20140163001A1,BrCc1ccccc1.CCOC(=O)Cc1csc(-c2cnn(C(C)(C)C)c2-c2ccc(F)cc2)n1>>CCOC(=O)C(Cc1ccccc1)c1csc(-c2cnn(C(C)(C)C)c2-c2ccc(F)cc2)n1,,CN(C)C=O,,O,[H-].[Na+],test
US05753664,Cc1cccc2nc(SCc3ccc(C(=O)c4ccc(O)cc4)cc3)n(C)c(=O)c12.ClCc1ccc(OCc2ccccc2)cc1>>Cc1cccc2nc(SCc3ccc(C(=O)c4ccc(OCc5ccc(OCc6ccccc6)cc5)cc4)cc3)n(C)c(=O)c12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140213580A1,COCCC(=O)N1CCN(c2nc(C3CC3)c(Br)cc2C#N)C[C@H]1C.OB(O)c1cccs1>>COCCC(=O)N1CCN(c2nc(C3CC3)c(-c3cccs3)cc2C#N)C[C@H]1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090082358A1,FC(F)(F)c1ccc([C@H]2NCCc3cccnc32)cc1.O=C=Nc1cccnc1>>O=C(Nc1cccnc1)N1CCc2cccnc2[C@H]1c1ccc(C(F)(F)F)cc1,,ClCCl,,,,test
US20140296315A1,CCOC(=O)C(C)(C)n1cc(-c2cc(OCCC(C)(C)O)cc3c2-c2ccccc2[C@]3(O)C(F)(F)F)cn1>>CC(C)(O)CCOc1cc(-c2cnn(C(C)(C)C(=O)O)c2)c2c(c1)[C@@](O)(C(F)(F)F)c1ccccc1-2,,CCO,,Cl,[Na+].[OH-],test
US20160083400A1,CCOC(=O)c1cc(C(C)C)on1.O=[N+]([O-])O>>CCOC(=O)c1noc(C(C)C)c1[N+](=O)[O-],,O=S(=O)(O)O,,,,test
US20080012473A1,C=C(C)C(=O)OCCCC.C=Cc1ccccc1>>C=C(C)C(=O)OCCCC.C=Cc1ccccc1,,CN(C)C=O,,,,test
US20110311461A1,O=C(CCl)Nc1ccccn1.O=C(O[C@H]1CN2CCC1CC2)C(Nc1ccccc1)c1csc2ccccc12>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C(Nc1ccccc1)c1csc3ccccc13)C2)Nc1ccccn1.[Cl-],,CCOC(C)=O,,,,test
US04294960,CON=C(C(=O)CBr)C(=O)NC1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=CCS[C@H]12.NC(N)=S>>CON=C(C(=O)NC1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=CCS[C@H]12)c1csc(N)n1,,CCO,O,,,test
US20080081818A1,CCOC(=O)CC#N.N=C(N)C1CC1>>Nc1cc(O)nc(C2CC2)n1,,CO,,Cl,C[O-].[Na+],test
US20040209920A1,C=CCBr.Cc1oc(-c2ccc(F)cc2)nc1COC1CCCC(O)C1>>C=CCOC1CCCC(OCc2nc(-c3ccc(F)cc3)oc2C)C1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20120157430A1,CC(=O)c1cc(Cl)c(C)c(Br)c1OS(=O)(=O)C(F)(F)F.OB(O)c1cc(F)cc(F)c1>>CC(=O)c1cc(Cl)c(C)c(Br)c1-c1cc(F)cc(F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,[Na],,test
US20050187298A1,CC(C)(C)c1cccc(O)c1.O=S(=O)(N(c1ccc(Cl)cn1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)c1cccc(OS(=O)(=O)C(F)(F)F)c1,CN(C)c1ccncc1,ClCCl,,,,test
US20100120778A1,O=P(Cl)(Cl)Cl.Oc1nc2ccccc2nc1C(F)(F)F>>FC(F)(F)c1nc2ccccc2nc1Cl,,O=P(Cl)(Cl)Cl,,ClP(Cl)(Cl)(Cl)Cl,,test
US20110009401A1,Nc1nc(C(=O)N2[C@@H]3CC[C@@H](C3)[C@H]2CNC(=O)C(F)(F)F)c(-c2cccc(F)c2)s1>>NC[C@@H]1[C@H]2CC[C@H](C2)N1C(=O)c1nc(N)sc1-c1cccc(F)c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20130252941A1,CC(O)c1cc(NC(=O)OC(C)(C)C)ncn1>>CC(O)c1cc(N)ncn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070179165A1,Cn1cc(I)c2c(=O)[nH]c(NC(=O)C(C)(C)C)nc21>>Cn1cc(I)c2c(=O)[nH]c(N)nc21,,C1CCOC1,,[Na+].[OH-],,test
US20070213341A1,C=C(N=Cc1cccc(Cl)c1)O[Si](C)(C)C.CCOC(=O)N1C(=O)/C(=C\c2ccc(Cl)cc2)c2ccc(Cl)cc21>>CCOC(=O)N1C(=O)C2(c3ccc(Cl)cc31)C(c1ccc(Cl)cc1)CC(=O)NC2c1cccc(Cl)c1,,Cc1ccccc1,,,,test
US20120232051A1,CC(C)(C)OC(=O)N(CC(F)(F)F)c1cnccc1I.COc1cc(F)c(F)cc1B(O)O>>COc1cc(F)c(F)cc1-c1ccncc1N(CC(F)(F)F)C(=O)OC(C)(C)C,,CCCCCCC,CCOC(C)=O,,,test
US20050184287A1,O=C(O)C=Cc1ccc(N(c2ccccc2)c2ccccc2)cc1.O=S(Cl)Cl>>O=C(Cl)C=Cc1ccc(N(c2ccccc2)c2ccccc2)cc1,,ClCCl,,CN(C)C=O,Cl,test
US20120190649A1,CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3cc(C=O)ccc3c2C(F)(F)F)CC1.COC(=O)C1CNC1>>COC(=O)C1CN(Cc2ccc3c(C(F)(F)F)c(O[C@@H]4CC[C@@H](C(C)(C)C)CC4)ccc3c2)C1,,CCO,,[BH3-]C#N.[Na+],,test
US20100331400A1,COC(=O)c1c(O)c2c(OCc3ccc(F)cc3)cccc2oc1=O.C[C@H](N)C(=O)O>>C[C@H](NC(=O)c1c(O)c2c(OCc3ccc(F)cc3)cccc2oc1=O)C(=O)O,,COCCO,,C[O-].[Na+],,test
US20160039838A1,Nc1ccc(F)c(Cl)c1.O=[N+]([O-])c1cc2c(Cl)ncnc2cc1Br>>O=[N+]([O-])c1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1Br,,CC(C)O,,,,test
US06350907B1,Cc1cc(/C=C/C[C@H](CC(=O)OC(C)(C)C)C(=O)N[C@H](C(=O)N[C@H](C)c2ccccc2)C(C)(C)C)ccc1Oc1ccccc1>>Cc1cc(CCC[C@H](CC(=O)OC(C)(C)C)C(=O)N[C@H](C(=O)N[C@H](C)c2ccccc2)C(C)(C)C)ccc1Oc1ccccc1,[Pd],CO,,O=C[O-].[NH4+],,test
US20100240671A1,O=C(O)C1(C(F)(F)F)CC1.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>O=C=NC1(C(F)(F)F)CC1,,Cc1ccccc1,,CCN(CC)CC,,test
US20090163512A1,COC(=O)c1ccc(Oc2ccc(Br)cc2C=O)cc1.O=C1Cc2ccc(Cl)cc2N1>>COC(=O)c1ccc(Oc2ccc(Br)cc2/C=C2\C(=O)Nc3cc(Cl)ccc32)cc1,,CO,,C1CCNC1,,test
US20130109678A1,CC(C)N1CCN(c2ccc3[nH]c(-c4ccc(N)c([N+](=O)[O-])c4)nc3c2)CC1>>CC(C)N1CCN(c2ccc3[nH]c(-c4ccc(N)c(N)c4)nc3c2)CC1,[Pd],CCOC(C)=O,CO,,,test
US20100137281A1,CCc1cc2c(=O)n(CC(=O)c3ccc(OC)cc3)c(=O)n(Cc3ccc(-c4ccccc4C#N)cc3)c2s1.O=C([O-])O.[NH3+]O>>CCc1cc2c(=O)n(CC(=O)c3ccc(OC)cc3)c(=O)n(Cc3ccc(-c4ccccc4-c4noc(=O)[nH]4)cc3)c2s1,,ClC(Cl)Cl,,CS(C)=O,[Cl-].[Na+],test
US20120225061A1,COC(=O)c1ccc(F)c(-c2c(F)cc(O)cc2F)n1.OC1CCOCC1>>COC(=O)c1ccc(F)c(-c2c(F)cc(OC3CCOCC3)cc2F)n1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160214935A1,C=C[Mg]Br.O=[N+]([O-])c1cccc(Cl)c1F>>Fc1c(Cl)ccc2cc[nH]c12,,C1CCOC1,,,,test
US20070225280A1,CCOC(=O)c1cnn(C)c1-n1cccn1>>Cn1ncc(C(=O)O)c1-n1cccn1,,CO,O,[Li+].[OH-],,test
US04537962,O=S(=O)(Cl)Cl.O=c1cc(CCl)nc2scnn12>>O=c1c(Cl)c(CCl)nc2scnn12,,CC(Cl)Cl,,,,test
US08697726B2,O=[N+]([O-])c1cc(F)c(OCc2ccccc2)cc1OCc1ccccc1>>Nc1cc(F)c(OCc2ccccc2)cc1OCc1ccccc1,[Zn],O,,[Cl-].[NH4+],,test
US20080139595A1,BrBr.CC(=O)Nc1ccc(Oc2ccnc3c2ccn3S(=O)(=O)c2ccc(C)cc2)c(F)c1>>CC(=O)Nc1ccc(Oc2ccnc3c2c(Br)cn3S(=O)(=O)c2ccc(C)cc2)c(F)c1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20090099190A1,CSc1ncc(CNc2cc(C#N)cc([N+](=O)[O-])c2)c(NC(C)C)n1.O=C(Cl)OC(Cl)(Cl)Cl>>CSc1ncc2c(n1)N(C(C)C)C(=O)N(c1cc(C#N)cc([N+](=O)[O-])c1)C2,,CCN(CC)CC,,,,test
US06020345,CCOCC.C[Mg]Br.N#CC1(C2OCCO2)C=CC=CN1>>CC(=O)c1cccc(C2OCCO2)n1,,CCOCC,,C1CCOC1,[Cl-].[NH4+],test
US20030100550A1,COC(=O)[C@@H]1CCCN2C(=O)CC[C@H](NC(=O)c3ccccc3)C(=O)N12>>O=C(N[C@H]1CCC(=O)N2CCC[C@@H](C(=O)O)N2C1=O)c1ccccc1,,CO,,[Li+].[OH-],,test
US20160016880A1,OCC12CCC(OCc3cccc(Oc4ccccc4)c3)(CC1)C2>>O=CC12CCC(OCc3cccc(Oc4ccccc4)c3)(CC1)C2,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20150376174A1,CCOC(=O)c1sc(-c2ccc(Oc3ccccc3)c([N+](=O)[O-])c2)nc1C>>CCOC(=O)c1sc(-c2ccc(Oc3ccccc3)c(N)c2)nc1C,[Pd],CCO,,,,test
US20120149681A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.OCc1cc(Cl)nc(C(F)(F)F)c1>>CC(C)(C)[Si](OCc1cc(Cl)nc(C(F)(F)F)c1)(c1ccccc1)c1ccccc1,CN(C)c1ccncc1,CCOCC,ClCCl,c1c[nH]cn1,,test
US20090012117A1,O=C(Cl)CCl.O=S(=O)(Nc1nccs1)c1ccc2c(c1)CCCN2>>O=C(CCl)N1CCCc2cc(S(=O)(=O)Nc3nccs3)ccc21,,ClCCl,,CCN(CC)CC,,test
US04025524,ClCCN1CC2CC3CC(C2)CC1C3.N#CC(c1ccccc1)c1ccccc1>>N#CC(CCN1CC2CC3CC(C2)CC1C3)(c1ccccc1)c1ccccc1,,Cc1ccccc1,O,Cl,[H-].[Na+],test
US20060217374A1,CCOC(=O)Cc1csc2cc(OCC(C)c3nc(-c4ccc(C(F)(F)F)cc4)sc3C)ccc12>>Cc1sc(-c2ccc(C(F)(F)F)cc2)nc1C(C)COc1ccc2c(CC(=O)O)csc2c1,,CCO,,Cl,[Na+].[OH-],test
US20060046977A1,C[Si](C)(C)C#Cc1ccccc1.O=c1c(I)c(OCc2ccccc2)ccn1Cc1ccccc1>>C[Si](C)(C)c1oc2c(c1-c1ccccc1)c(=O)ccn2Cc1ccccc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,,CCN(CC)CC,,test
US20130059834A1,Cc1ccc2c(-c3cnc4c(n3)c(C(=O)NC(C)(C)CO[Si](C)(C)C(C)(C)C)cn4C(c3ccccc3)(c3ccccc3)c3ccccc3)nn(CC(=O)N3CCOCC3)c2c1.Cl>>Cc1ccc2c(-c3cnc4[nH]cc(C(=O)NC(C)(C)CO)c4n3)nn(CC(=O)N3CCOCC3)c2c1.Cl,,C1COCCO1,,,,test
US20150119435A1,CS(=O)(=O)OCCOCCOCCN=[N+]=[N-].Oc1ccc2ccccc2n1>>[N-]=[N+]=NCCOCCOCCOc1cccc2cccnc12,,O,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20030013719A1,COc1ccc(CC(=O)Cl)cc1.COc1ccc(NC(=O)c2cccc(-c3ccccc3CN)n2)cc1>>COc1ccc(CC(=O)NCc2ccccc2-c2cccc(C(=O)Nc3ccc(OC)cc3)n2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080287394A1,Cc1cn(C)c(=O)cn1>>CC1CN(C)C(=O)CN1,O=[Pt],CCOC(C)=O,,,,test
US20030130277A1,COc1ccc(-c2cccc3[nH]c4cnn(C)c4c(=O)c23)cc1>>Cn1ncc2[nH]c3cccc(-c4ccc(O)cc4)c3c(=O)c21,,Br,CC(=O)O,O,,test
US20070225201A1,CC1(C)CCCC2(C1)CC2(C)C(=O)O.CCOC(=O)CO>>CCOC(=O)COC(=O)C1(C)CC12CCCC(C)(C)C2,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20100160322A1,COC(=O)c1ccc(F)cc1Oc1cccc(NC(c2ccc(OC)cc2)c2ccc(OC)cc2)c1N.O=C(Cl)Cl>>COC(=O)c1ccc(F)cc1Oc1cccc2c1[nH]c(=O)n2C(c1ccc(OC)cc1)c1ccc(OC)cc1,,Cc1ccccc1,ClCCl,CCN(C(C)C)C(C)C,,test
US20100298391A1,C[C@H](N)C1CCCCC1.Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)O>>Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)N[C@@H](C)C1CCCCC1,,CN(C)C=O,,CCN=C=NCCCN(C)C,,test
US20030229079A1,Brc1cc(Br)cc(Cc2ccccc2)c1.CN(C)C=O>>O=Cc1cc(Br)cc(Cc2ccccc2)c1,,C1CCOC1,CCOC(C)=O,[Li]CCCC,,test
US06177423B1,C1CCNC1.C=CCON1C(=O)c2ccc([N+](=O)[O-])c3cc(C)cc(c23)C1=O>>C=CCON1C(=O)c2ccc(N3CCCC3)c3cc(C)cc(c23)C1=O,,CN(C)C=O,,CCN(CC)CC,,test
US04771058,COC1=NS(=O)N=C1OC.Cc1cc(Br)cnc1NCCCCN.N>>Cc1cc(Br)cnc1NCCCCNC1=NS(=O)N=C1N,,CO,,,,test
US20080058320A1,CI.COCCCCc1cc(I)nc(I)c1O>>COCCCCc1cc(I)nc(I)c1OC,,CCOC(C)=O,CN(C)C=O,O,[Na+].[OH-],test
US05459137,CC(=O)OC(C)=O.CC1Cc2cc3c(cc2C(c2ccc(N)cc2)=NN1)OCO3>>CC(=O)N1N=C(c2ccc(N)cc2)c2cc3c(cc2CC1C)OCO3,,CCN(CC)CC,,ClC(Cl)Cl,,test
US20030199512A1,CCC(C)=O.CO.NNc1nncc2ccccc12>>CCCCCCC.CCO,,CO,O,Cl,,test
US20070043040A1,CC(C)(C)OC(=O)N(CCNS(=O)(=O)c1cccc2cnccc12)CCOc1ccccc1Cc1ccccc1.CI>>CN(CCN(CCOc1ccccc1Cc1ccccc1)C(=O)OC(C)(C)C)S(=O)(=O)c1cccc2cnccc12,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20070244140A1,NS(=O)(=O)c1ccc(Nc2nccc(Cl)n2)cc1.OB(O)c1ccc(O)cc1>>NS(=O)(=O)c1ccc(Nc2nccc(-c3ccc(O)cc3)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20150014649A1,Brc1cccc(-n2c3ccccc3c3ccccc32)c1.CC1(C)OB(c2cccc3c2oc2c(-c4ccc5c6ccccc6c6ccccc6c5c4)cccc23)OC1(C)C>>c1cc(-c2cccc3c2oc2c(-c4ccc5c6ccccc6c6ccccc6c5c4)cccc23)cc(-n2c3ccccc3c3ccccc32)c1,,Cc1ccccc1,O,COc1cccc(OC)c1-c1ccccc1P(C1CCCCC1)C1CCCCC1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US05599993,Nc1cccc(O)c1.O=C(c1ccc(F)cc1)c1ccc(C#Cc2ccccc2)cc1>>Nc1cccc(Oc2ccc(C(=O)c3ccc(C#Cc4ccccc4)cc3)cc2)c1,,CC(=O)N(C)C,O,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20160184318A1,Cc1nnn[nH]1.FC(F)Oc1ccc(Br)c(CBr)c1>>Cc1nnn(Cc2cc(OC(F)F)ccc2Br)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04962109,CCOC(=O)C(O)(c1cnc(C(C)(C)C)nc1)C(C)(C)C.O=S(Cl)Cl>>CCOC(=O)C(Cl)(c1cnc(C(C)(C)C)nc1)C(C)(C)C,,CC#N,,O,c1c[nH]cn1,test
US04742067,CCCCC1N=C(c2ccccc2)OC1=O.CN(CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1>>CCCCC(NC(=O)c1ccccc1)C(=O)CN(C)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1,CN(C)C=O,CCN(CC)CC,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US04395549,N#Cc1ccc(NN=C2CCCn3c2nc2ccccc2c3=O)cc1>>N#Cc1ccc2[nH]c3c(c2c1)CCn1c-3nc2ccccc2c1=O,,O,,[NH4+].[OH-],,test
US20090275578A1,COc1ccc(COc2cc(Cl)c3c(c2)CN(Cc2ccc(OC(F)(F)F)cc2)C3=O)cc1>>O=C1c2c(Cl)cc(O)cc2CN1Cc1ccc(OC(F)(F)F)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20090163488A1,ClCc1ccccc1CCl.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3c2)c1>>O=C(Nc1cn2cc(Oc3cccc(N4Cc5ccccc5C4)c3)ccc2n1)C1CC1,,CCOC(C)=O,,CN(C)C=O,,test
US20060128790A1,CC(=O)Oc1c(C(C)C)cc(O)c(C(C)=O)c1C.O=C1CCC1>>CC(=O)Oc1c(C(C)C)cc2c(c1C)C(=O)CC1(CCC1)O2,,Cc1ccccc1,,C1CCNC1,,test
US20120172599A1,CCCCN(CCCC)c1ccc(C=Cc2cccs2)c(OC)c1.CN(C)C=O>>CCCCN(CCCC)c1ccc(C=Cc2ccc(C=O)s2)c(OC)c1,,C1CCOC1,,[Li]CCCC,,test
US20040014967A1,CC(C)COC(=O)Nc1ccc(I)c(F)c1.CCCC(=O)OC[C@H]1CO1>>O=C1O[C@@H](CO)CN1c1ccc(I)c(F)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04853386,C=CCN(c1ncnc2c1ncn2CC(C)O)C1CCCCC1.CC(=O)OC(C)=O>>C=CCN(c1ncnc2c1ncn2CC(C)OC(C)=O)C1CCCCC1,,O,,c1ccncc1,,test
US20040038987A1,C1N2CN3CN1CN(C2)C3.CC(=O)O.CC(C)c1cccc(C(C)C)c1N>>CC(C)c1cc(C=O)cc(C(C)C)c1N,,O,,,,test
US06083986,CC(=O)O[C@@H]1Cc2ccc([N+](=O)[O-])cc2[C@H]1NC(=O)c1ccccc1>>CC(=O)O[C@@H]1Cc2ccc(N)cc2[C@H]1NC(=O)c1ccccc1,O=[Pt]=O,CCOC(C)=O,,,,test
US05302593,BrCCCCCCBr.O=C1NC(=O)c2ccccc21>>O=C1NC(=O)c2c(CCCCCCBr)cccc21,,CN(C)C=O,,[K],,test
US20030013720A1,CN(CCCl)CCCl.N#CCc1ccc(I)cc1>>CN1CCC(C#N)(c2ccc(I)cc2)CC1,,CS(C)=O,,Cl,,test
US20070155839A1,CCOC(=O)/C=C/c1ccc(C(=C2CCCCCC2)c2ccc(O)c(Cl)c2)cc1>>O=C(O)/C=C/c1ccc(C(=C2CCCCCC2)c2ccc(O)c(Cl)c2)cc1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20030096826A1,CON(C)C(=O)[C@H](CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccccc1OCCc1cncc2ccccc12>>CC(C)(C)OC(=O)C[C@@H](C=O)NS(=O)(=O)c1ccccc1OCCc1cncc2ccccc12,,CCOCC,,C1CCOC1,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050032786A1,CCS(=O)(=O)Cl.NCc1cccc(-c2nc(=O)c3ccccc3s2)n1>>CCS(=O)(=O)NCc1cccc(-c2nc(=O)c3ccccc3s2)n1,,CCOC(C)=O,O,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20030130270A1,COc1ccc2ccnc(Cl)c2c1.N>>COc1ccc2ccnc(N)c2c1,,CCO,,,,test
US20070270587A1,CC1(C)CN=C2N(C1)c1ccc(S(=O)(=O)N3CCC[C@H]3COCc3ccccc3)cc1C21OCCCO1>>CC1(C)CN=C2N(C1)c1ccc(S(=O)(=O)N3CCC[C@H]3CO)cc1C21OCCCO1,[Pd],CCO,,,,test
US20140073620A1,CCC(C(N)=O)c1ccccc1C#C[Si](C)(C)C>>C#Cc1ccccc1C(CC)C(N)=O,,ClCCl,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20070155805A1,CCCCC(CCOc1ccc(OCC(=O)OCC)c(C)c1)c1cc2ccc(F)cc2s1>>CCCCC(CCOc1ccc(OCC(=O)O)c(C)c1)c1cc2ccc(F)cc2s1,,CO,,[Na+].[OH-],,test
US20070232627A1,COC(=O)c1ccc(Sc2ccc(NC(=O)OC(C)(C)C)cc2)c(Nc2ncnc3cc(C(C)C)ccc23)c1>>CC(C)c1ccc2c(Nc3cc(C(=O)O)ccc3Sc3ccc(NC(=O)OC(C)(C)C)cc3)ncnc2c1,,C1COCCO1,O,Cl,[Li+].[OH-],test
US20130131051A1,COC(=O)C1=C(C)c2cc(N)ccc2CCC1>>CC1=C(CO)CCCc2ccc(N)cc21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070254937A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Ic1n[nH]c2cc(-c3ccccc3)sc12>>CC(C)(C)OC(=O)n1nc(I)c2sc(-c3ccccc3)cc21,CN(C)c1ccncc1,ClCCl,,,,test
US20120142671A1,CC(C)(C)OC(=O)N[C@@H](C(N)=O)C1CC1.Cl>>Cl.NC(=O)[C@H](N)C1CC1,,C1COCCO1,,,,test
US20110044899A1,CCN(CC)CCN.O=C(O)c1cc(=O)[nH]c2ccc(I)cc12.O=S(Cl)Cl>>CCN(CC)CCNC(=O)c1cc(Cl)nc2ccc(I)cc12,CN(C)C=O,C1CCOC1,ClCCl,,,test
US20150018422A1,CCOC(=O)CC(c1cccc(COc2cnc(O)c(CC(C)(C)C)c2)c1)C1CC1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)CC(c1cccc(COc2cnc(OS(=O)(=O)C(F)(F)F)c(CC(C)(C)C)c2)c1)C1CC1,,c1ccncc1,,O,,test
US20150225394A1,CC(C)(C)OC(=O)N1CCC(CC#N)(N2CC(CN(C(=O)C(F)(F)F)[C@@H]3C[C@H]3c3ccccc3)C2)CC1>>N#CCC1(N2CC(CN(C(=O)C(F)(F)F)[C@@H]3C[C@H]3c3ccccc3)C2)CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080249093A1,CCOC(=O)c1cnc(OC(C)C)c(I)c1>>CC(C)Oc1ncc(C(=O)O)cc1I,,CC(C)O,,[Na+].[OH-],,test
US20140142137A1,BrCc1ccccc1.O=C(O)c1cccc(C(=O)O)n1>>O=C(O)c1cccc(C(=O)OCc2ccccc2)n1,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US20140088079A1,CCc1ccc([Mg]Br)cc1.OC1OCc2ccc(Br)cc21>>CCc1ccc(C(O)c2cc(Br)ccc2CO)cc1,,C1CCOC1,,,,test
US20160176867A1,CO.O=[N+]([O-])c1cc(S(=O)(=O)N2CCOCC2)ccc1Cl>>COc1ccc(S(=O)(=O)N2CCOCC2)cc1[N+](=O)[O-],,CO,,C[O-].[Na+],,test
US06004988,CCOC(=O)CC(C)(c1ccccc1)c1ccccc1>>CC(CC(=O)O)(c1ccccc1)c1ccccc1,,C1COCCO1,,[K+].[OH-],,test
US06544981B2,COC(=O)c1ccc(C(=O)C(C#N)=C(Nc2ccc3oc(C)cc3c2)N[C@H]2CCCCN(CC(=O)N3CCCC3)C2=O)cc1>>Cc1cc2cc(NC(N[C@H]3CCCCN(CC(=O)N4CCCC4)C3=O)=C(C#N)C(=O)c3ccc(C(=O)O)cc3)ccc2o1,,O,,C1CCOC1,,test
US20090137530A1,CCCCCCCCO.N#Cc1cc(Br)ccc1F>>CCCCCCCCOc1ccc(Br)cc1C#N,,CN(C)C=O,,O,[H-].[Na+],test
US04004912,CC(=O)OC(C)=O.CN1CCC(O)N(c2nnc(C3CC3)s2)C1=O>>CC(=O)OC1CCN(C)C(=O)N1c1nnc(C2CC2)s1,,c1ccccc1,,Cc1ccccc1S(=O)(=O)O,,test
US20070010576A1,C=C=C1CC(c2ccccc2)OC1CCO.CCOC(C)=O>>C=C(C(=O)OCC)C12CC(c3ccccc3)OC1CCO2,Cl[Pd]Cl,CO,,O,,test
US20090264399A1,C[C@@H]1CCCC[C@@H]1n1c(=O)[nH]c2cnc3c(ccn3COCC[Si](C)(C)C)c21.N#Cc1ccc(CBr)cc1>>C[C@@H]1CCCC[C@@H]1n1c(=O)n(Cc2ccc(C#N)cc2)c2cnc3c(ccn3COCC[Si](C)(C)C)c21,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20090253659A1,CC(C)=O.CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(-c3ccc[nH]3)cc2)CC(C)(C)C1.CCOC(=O)C(C)(C)Br>>CCOC(=O)C(C)(C)Oc1ccc(C(=C2CC(C)(C)CC(C)(C)C2)c2ccc(O)cc2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120108596A1,Fc1nc(NC2=NC[C@@]3(CN4CCC3CC4)O2)cc2ccccc12.O=C(OO)c1cccc(Cl)c1>>[O-][N+]12CCC(CC1)[C@]1(CN=C(Nc3cc4ccccc4c(F)n3)O1)C2,,ClC(Cl)Cl,,,,test
US20040106795A1,CCCCOc1c(O)cc(C=O)cc1Cl.CCOC(=O)CBr>>CCCCOc1c(Cl)cc(C=O)cc1OCC(=O)OCC,,CN(C)C=O,,[H-].[Na+],,test
US20140221310A1,CC(C)(C)[Si](C)(C)Oc1c(C2CCCCC2)ccc(-c2cnc(N)cn2)c1F>>Nc1cnc(-c2ccc(C3CCCCC3)c(O)c2F)cn1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110053897A1,CC1(C)OB(c2c[nH]nc2C(F)(F)F)OC1(C)C.Nc1cc(Cl)ncn1>>Nc1cc(-c2c[nH]nc2C(F)(F)F)ncn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20110046122A1,CC(CO)(NC(=O)CCl)c1cccc(Br)c1>>C[C@](CO)(NC(=O)CCl)c1cccc(Br)c1,,ClCCl,,,,test
US20140194432A1,CCOC(=O)/C(=C\N(C)C)C(=O)c1ncccc1Cl.NCc1ccccc1Br>>CCOC(=O)c1cn(Cc2ccccc2Br)c2cccnc2c1=O,,CC(=O)N(C)C,,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20100009206A1,O=[N+]([O-])c1ccc(Oc2cc(Oc3ccc([N+](=O)[O-])cc3)cc(Oc3ccc([N+](=O)[O-])cc3)c2)cc1>>Nc1ccc(Oc2cc(Oc3ccc(N)cc3)cc(Oc3ccc(N)cc3)c2)cc1,[Pd],C1CCOC1,,CCO,[H][H],test
US20090042964A1,O=C(O)C(F)(F)Cl.Oc1ccc(Br)cc1Cl>>FC(F)Oc1ccc(Br)cc1Cl,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20160145247A1,C[C@H](NC(=O)OC(C)(C)C)c1cccc(-c2cc(C=Cc3ccncc3)cc(COc3ccccc3CC(=O)OC(C)(C)C)c2)c1F>>C[C@H](NC(=O)OC(C)(C)C)c1cccc(-c2cc(CCc3ccncc3)cc(COc3ccccc3CC(=O)OC(C)(C)C)c2)c1F,[Pd],CCOC(C)=O,,,,test
US04423066,CC1(C)C(C=C(Cl)c2ccc(Cl)cc2)C1C(=O)O.Fc1c(F)c(F)c(CBr)c(F)c1F>>CC1(C)C(C=C(Cl)c2ccc(Cl)cc2)C1C(=O)OCc1c(F)c(F)c(F)c(F)c1F,,CN(C)C=O,,[K],,test
US20060154955A1,COC(=O)/C(=C/c1nc(-c2ccccc2)ccc1NC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1>>COC(=O)C(Cc1nc(-c2ccccc2)ccc1NC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1,[Pt],C1CCOC1,CO,,,test
US20100035865A1,COC(=O)[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1c1ccccc1.II>>COC(=O)[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1c1ccc(I)cc1,,ClCCl,,,,test
US20060287300A1,C1COCCN1.CC(C)CC[C@@]1(N)C(=O)C(C2=NS(=O)(=O)c3cc(NC(=O)OC(C)(C)C)ccc3N2)=C(O)c2ccccc21.CS(=O)(=O)Cl.O=S(=O)(Cl)CCCl>>CC(C)CC[C@@]1(NS(=O)(=O)CCN2CCOCC2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21,,ClCCl,,CCN(CC)CC,c1ccncc1,test
US20040082780A1,CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4O)ncn3)cccc2s1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4OS(=O)(=O)C(F)(F)F)ncn3)cccc2s1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,O,test
US20050203095A1,CC(C)(C)OC(=O)NN.O=Cc1ccc2ccccc2n1>>CC(C)(C)OC(=O)NN=Cc1ccc2ccccc2n1,,CCO,,,,test
US20110190278A1,COC(=O)C1(O)CC1.COC(=O)c1cc([N+](=O)[O-])c(F)cc1C>>COC(=O)c1cc([N+](=O)[O-])c(OC2(C(=O)OC)CC2)cc1C,,C1CCOC1,O,Cl,[H-].[Na+],test
US20020055631A1,CC(C)(C)OC(=O)N1CCC(C#N)CC1.c1ccc(SSc2ccccc2)cc1>>CC(C)(C)OC(=O)N1CCC(C#N)(Sc2ccccc2)CC1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US05166437,CN1CCCC1=O.Cc1ccccc1.FC(F)(F)c1ccc(Cl)cc1.O>>CNCCC(Oc1ccc(C(F)(F)F)cc1)c1ccccc1,,O,,CC(C)(C)[O-].[K+],,test
US20030170831A1,C=CC[C@@H]1C=C(C)C[C@H](C)C[C@H](OC)[C@H]2O[C@@](O)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@H](/C(C)=C/[C@@H]3CC[C@@H](O)[C@H](OC)C3)[C@H](C)[C@@H](O)CC1=O)[C@H](C)C[C@@H]2OC.C[Si](C)(C)CCOC(=O)CCCN=C=O>>C=CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(OC(=O)NCCCC(=O)OCC[Si](C)(C)C)C(OC)C3)C(C)C(O)CC1=O)C(C)CC2OC,CCN(CC)CC,c1ccccc1,,,,test
US20110105462A1,CCCN.Cc1ccc(S(=O)(=O)OC[C@H]2COc3ccc(C(F)(F)F)cc3O2)cc1>>CCCNC[C@H]1COc2ccc(C(F)(F)F)cc2O1,,CC#N,,,,test
US20080132546A1,CCNC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cn1.CCOC(=O)c1sc(Cl)nc1C(=O)N(C)C>>CCNC(=O)Nc1ccc(-c2nc(C(=O)N(C)C)c(C(=O)OCC)s2)cn1,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20070270438A1,N#Cc1ccc(C(=O)O)cc1>>N#Cc1ccc(CO)cc1,,C1CCOC1,,CCOCC,FB(F)F,test
US20110105535A1,CCC(=N)NO.CCOC(=O)CCNC(=O)OC(C)(C)C>>CCc1noc(CCNC(=O)OC(C)(C)C)n1,,CN(C)C=O,,O,[H-].[Na+],test
US20130085135A1,C[C@@H]1CCc2ncnc(-c3ccc(C(=O)N[C@H](CN=[N+]=[N-])Cc4ccc(Cl)cc4Cl)s3)c21>>C[C@@H]1CCc2ncnc(-c3ccc(C(=O)N[C@H](CN)Cc4ccc(Cl)cc4Cl)s3)c21,[Pd],CO,,,,test
US20040116475A1,CC(C)CBr.COc1ccc(-n2nc(O)cc2-c2ccc(OCc3ccccc3)cc2)cc1>>COc1ccc(-n2nc(OCC(C)C)cc2-c2ccc(OCc3ccccc3)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100298324A1,COC(=O)c1ccc(C(=O)OC)c(N=C=S)c1.COc1cc(OC)nc(N)n1>>COc1cc(OC)nc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)n1,,CN(C)C=O,,Cl,[Na+].[OH-],test
US20120114739A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Fc1ccc2ncc(Br)cc2c1>>CC1(C)OB(c2cnc3ccc(F)cc3c2)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20110070190A1,Nc1ccc(-c2cc3c(s2)c(=O)ncn3Cc2ccc(Cl)cc2)cc1Cl.O=C(Cl)c1ccccn1>>O=C(Nc1ccc(-c2cc3c(s2)c(=O)ncn3Cc2ccc(Cl)cc2)cc1Cl)c1ccccn1,,ClCCl,,Cl,,test
US04634710,CO.Cc1c([N+](=O)[O-])cc[n+]([O-])c1C>>COc1cc[n+]([O-])c(C)c1C,,CO,,C[O-].[Na+],,test
US20070060629A1,Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccccc2)cc1.O=S(=O)(O)Cl>>Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccccc2)cc1S(=O)(=O)Cl,,ClC(Cl)Cl,,,,test
US20110230483A1,C1CCNC1.Cc1ccc(C)n1-c1cc(C(F)(F)F)c(Br)nc1C(=O)O>>Cc1ccc(C)n1-c1cc(C(F)(F)F)c(N2CCCC2)nc1C(=O)O,,C1CCOC1,,,,test
US20040087798A1,O=C(Cc1ccccc1)Nc1cccc([N+](=O)[O-])c1>>Nc1cccc(NC(=O)Cc2ccccc2)c1,[Fe],O,,CCO,[Cl-].[NH4+],test
US20120328691A1,O=[N+]([O-])c1ccccc1F.c1cn(C2CCNCC2)cn1>>O=[N+]([O-])c1ccccc1N1CCC(n2ccnc2)CC1,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20100081675A1,CC#N.COC(=O)c1sccc1N=CN(C)C>>N#Cc1c[nH]c2ccsc2c1=O,,C1CCOC1,CC(=O)O,CCCCCC,[Li]CCCC,test
US20140294966A1,CS(C)=O.Cl.ClCCCl.Nc1nc2ncc(CNc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)nc2c(=O)[nH]1>>CCN=C=NCCCN(C)C.Cl,,Cl,,[Na+].[OH-],,test
US05527919,CCCCC(=O)N(Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCCC)cc1)C(C#N)C(=O)OCC.CS>>CCCCC(=O)N(Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCCC)cc1)C(C(=O)OCC)=C(N)SC,,ClCCl,,CCN(CC)CC,,test
US20150329552A1,CCOC(=O)c1cc2n(c1)CCc1c(N)n[nH]c1-2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1cc2n(c1)CCc1c(NC(=O)C(F)(F)F)n[nH]c1-2,,ClCCl,,,,test
US20050197346A1,Cc1ccccc1OCCBr.Cc1nc2cc(OC[C@H](O)CN3CCNCC3)ccc2s1>>Cc1nc2cc(OC[C@H](O)CN3CCN(CCOc4ccccc4C)CC3)ccc2s1,,CCO,,CCN(C(C)C)C(C)C,,test
US20050277674A1,COc1ccc2[nH]cc(C3CCN(C(=O)NCC4CCC(c5ccccc5)(N(C)C)CC4)CC3)c2c1.O=C(O)CC(O)(CC(=O)O)C(=O)O>>COc1ccc2[nH]cc(C3CCN(C(=O)NCC4CCC(c5ccccc5)(N(C)C)CC4)CC3)c2c1.O=C(O)CC(O)(CC(=O)O)C(=O)O,,ClCCl,,CCO,,test
US20100298324A1,COC(=O)c1ccc(C(=O)OC)c(N=C=S)c1.COc1cc(N)nc(OC)n1>>COc1cc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)nc(OC)n1,,CS(C)=O,O,Cl,[Na+].[OH-],test
US20080045556A1,Brc1ccc(-c2csc(Br)n2)cc1.C[C@H](N)CO>>C[C@@H](CO)Nc1nc(-c2ccc(Br)cc2)cs1,,ClCCl,,,,test
US20150158863A1,COC(=O)CN.Cc1ccc([N+](=O)[O-])c(Cl)n1>>COC(=O)CNc1nc(C)ccc1[N+](=O)[O-],,CN(C)C=O,,CCN(CC)CC,Cl,test
US20160024016A1,CN(CCN(C)C(=O)OC(C)(C)C)Cc1cn(C2CCCCO2)nc1C1=CC(O[Si](C)(C)C(C)(C)C)C(C)(C)CC1>>CN(CCN(C)C(=O)OC(C)(C)C)Cc1cn(C2CCCCO2)nc1C1CCC(C)(C)C(O[Si](C)(C)C(C)(C)C)C1,[Pd],CCO,,,,test
US20090318412A1,CC(C)(C)OC(=O)N1CCN2C(=O)c3c(Br)cccc3OCC2C1.OB(O)c1ccoc1>>CC(C)(C)OC(=O)N1CCN2C(=O)c3c(cccc3-c3ccoc3)OCC2C1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20060094750A1,O=P(Cl)(Cl)Cl.O=c1[nH]cc(Br)cc1[N+](=O)[O-]>>O=[N+]([O-])c1cc(Br)cnc1Cl,,CN(C)C=O,,,,test
US20150099758A1,O=C(O)c1cc(Cl)nnc1NCc1ccccc1>>O=C(O)c1ccnnc1NCc1ccccc1,,CO,,O=C[O-].[NH4+],,test
US20040110807A1,CCOC(=O)C(Cc1ccc(O)cc1OCC)OCC.Cc1sc(-c2ccccc2)nc1CCO>>CCOC(=O)C(Cc1ccc(OCCc2nc(-c3ccccc3)sc2C)cc1OCC)OCC,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150119373A1,C=C(C)[C@@H]1CC[C@]2(C(=O)N[C@@H]3C[C@H](C(=O)N4CCCCC4)C3(C)C)CC[C@]3(C)[C@H](CC[C@H]4[C@@]3(C)CC[C@H]3C(C)(C)[C@@H](OC(=O)CC(C)(C)C(=O)O)CC[C@@]34C)[C@@H]12.O=C(OO)c1cccc(Cl)c1>>CC(C)(CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC[C@@H]2[C@H]4[C@H](C5(C)CO5)CC[C@]4(C(=O)N[C@@H]4C[C@H](C(=O)N5CCCCC5)C4(C)C)CC[C@]23C)C1(C)C)C(=O)O,,ClCCl,ClCCl,,,test
US20130345261A1,COc1ccc2nc(S)[nH]c2c1.Cc1ccc(CBr)cc1>>COc1ccc2[nH]c(SCc3ccc(C)cc3)nc2c1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US06344468B1,Brc1cccnc1.COc1cccc(CCN2C(=O)c3ccccc3C2=O)c1>>COc1cccc(CCN2C(=O)c3ccccc3C2(O)c2cccnc2)c1,,C1CCOC1,CCOCC,[Li]CCCC,[Cl-].[NH4+],test
US20120238488A1,CC(C)(C)OC(=O)N1CC[C@H](OS(C)(=O)=O)C1.ON=C(c1ccccc1)c1ccccc1>>c1ccc(C(=NO[C@@H]2CCNC2)c2ccccc2)cc1,,CS(C)=O,,O,[K+].[OH-],test
US05925674,Nc1ccc(O)c(Cl)c1Cl.O=C(Cl)C1(Br)CCCCC1>>Nc1cc(O)c(Cl)c(Cl)c1C(=O)C1(Br)CCCCC1,,C1CCOC1,,CCN(CC)CC,,test
US20050245518A1,COC(=O)c1ccc(CBr)cc1.N#Cc1c[nH]nc1N>>COC(=O)c1ccc(Cn2cc(C#N)c(N)n2)cc1,,CC(C)=O,CCOCC,CN(C)C=O,,test
US20110230414A1,C[C@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(C3CC3)nc12)C(=O)OC(C)(C)C>>C[C@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(C3CC3)nc12)C(=O)O,,OCC(F)(F)F,,,,test
US20130150357A1,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.CCC(=O)c1cccc(Cl)c1>>C/C=C(\O[Si](C)(C)C(C)(C)C)c1cccc(Cl)c1,,ClCCl,,CCN(CC)CC,,test
US20140194418A1,CC(C)(C)OC(=O)N1CC=C(c2ccc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(Cl)c2)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(Cl)c2)CC1,[Pd],CO,,,,test
US20150057260A1,COC(=O)c1nc(Cl)c(N)nc1N.COC(CBr)OC>>COC(=O)c1nc(Cl)c2nccn2c1N,,CC#N,,,,test
US20020082271A1,CC(=O)Oc1cc2ncnc(O)c2cc1OCC1CCCC1.O=S(Cl)Cl>>CC(=O)Oc1cc2ncnc(Cl)c2cc1OCC1CCCC1,CN(C)C=O,,,,,test
US20020193402A1,O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O[C@@H]1CC[C@H]2CC[C@]1(c1ccc(F)cc1)N2Cc1ccccc1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@@H]1CC[C@@H]2CC[C@@]1(c1ccc(F)cc1)N2Cc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US20080176833A1,C[Si](C)(C)C#N.C[Si](C)(C)CCOC[NH+]1NC=C2C1=CC=CN2O>>N#Cc1ccc2[nH]ncc2n1,,ClCCl,,,,test
US20140038941A1,BrBr.CC[Si](CC)(CC)OC(=CCC1CCC(F)(F)CC1)C1(C(F)(F)F)CC1>>O=C(C(Br)CC1CCC(F)(F)CC1)C1(C(F)(F)F)CC1,,ClCCl,,,,test
US20040063707A1,CC(C)[Si](Cl)(C(C)C)C(C)C.Cc1cc2c(F)ccnc2[nH]1>>Cc1cc2c(F)ccnc2n1[Si](C(C)C)(C(C)C)C(C)C,,C1CCOC1,CCOC(C)=O,[H-].[Na+],[Cl-].[NH4+],test
US20040152704A1,C1CCNC1.O=CCc1cnc2cc(Br)cnc2c1>>Brc1cnc2cc(CCN3CCCC3)cnc2c1,,C1CCOC1,ClCCl,CC(=O)O,,test
US20130231328A1,CC(C)(C)OC(=O)NC1CCC(O)CC1.CC(C)(C)[Si](C)(C)OCC[C@H]1CCc2sc3ncnc(Cl)c3c2C1>>CC(C)(C)OC(=O)NC1CCC(Oc2ncnc3sc4c(c23)C[C@@H](CCO[Si](C)(C)C(C)(C)C)CC4)CC1,,C1CCOC1,,[H-].[Na+],,test
US20130109668A1,CC(C)(C)OC(=O)N1CC2(CN(C(=O)NCc3ccc(Cl)cc3Cl)C2)C1>>O=C(NCc1ccc(Cl)cc1Cl)N1CC2(CNC2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050020660A1,Br[Mg]c1ccccc1.C1CCOC1.CCOCC.C[N-]OC>>O=C(c1ccccc1)C1CCC=CCC1,,C1CCOC1,,Cl,,test
US20100022613A1,CCOC(=O)Cn1c(C)c(Cc2ccccc2S(=O)(=O)Cc2ccccc2)c2cc(F)ccc21>>Cc1c(Cc2ccccc2S(=O)(=O)Cc2ccccc2)c2cc(F)ccc2n1CC(=O)O,,C1CCOC1,,[K+].[OH-],,test
US20060211694A1,O=C1CCC(=O)N1Br.O=c1cc(O)ccn1Cc1cccc(F)c1>>O=c1c(Br)c(O)ccn1Cc1cccc(F)c1,,ClCCl,,,,test
US20090088439A1,CCCI.O=c1[nH]c2nc3c(nc2c(=O)n1Cc1ccc(Cl)cc1)CCCC3>>CCCn1c(=O)n(Cc2ccc(Cl)cc2)c(=O)c2nc3c(nc21)CCCC3,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120190724A1,ClCC1CS1.O=c1c2c(O)cc(O)cc2oc2ccc3ccccc3c12>>O=c1c2c(O)cc(OCC3CS3)cc2oc2ccc3ccccc3c12,,CC(C)=O,,,,test
US04898455,COC=Cc1ccc(-c2ccc(Br)cc2)nc1>>O=CCc1ccc(-c2ccc(Br)cc2)nc1,,C1CCOC1,,,,test
US20070219234A1,CC(C)(C)OC(=O)N1CCCNCC1.Fc1nc(F)c(F)c(F)c1F>>CC(C)(C)OC(=O)N1CCCN(c2c(F)c(F)nc(F)c2F)CC1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20160264548A1,C/C=C/C(=O)Cl.NC(=O)c1cc(N2CCCC(N)C2)cnc1Oc1ccc(Oc2ccccc2)cc1>>C/C=C/C(=O)NC1CCCN(c2cnc(Oc3ccc(Oc4ccccc4)cc3)c(C(N)=O)c2)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040214832A1,COc1ccccc1COCCCOc1ccc(N2CCN(C(=O)OC(C)(C)C)C[C@@H]2COc2ccc3ccccc3c2)cc1>>COc1ccccc1COCCCOc1ccc(N2CCNC[C@@H]2COc2ccc3ccccc3c2)cc1,,CO,,CC(=O)Cl,,test
US20060128695A1,COc1cc2c(cc1OC)N(C)C(=O)CN=C2c1cccc(C#N)c1.OO>>COc1cc2c(cc1OC)N(C)C(=O)CN=C2c1cccc(C(N)=O)c1,,CCO,O,[Na+].[OH-],,test
US20110312963A1,CN(C)[C@@H]1CCN(C(=O)Nc2cc(Oc3ccc(N)c4ccccc34)ccn2)C1.Cc1ccc(-n2nc(C(C)(C)C)cc2N)cc1.O=C(n1ccnc1)n1ccnc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(NC(=O)N4CC[C@@H](N(C)C)C4)c3)c3ccccc23)cc1,,ClCCl,,,,test
US20040186186A1,O.OC1CCCC1.Oc1cccc(O)c1>>O.Oc1ccc(C2CCCC2)c(O)c1,,Cc1ccccc1,O,O=P(O)(O)O,,test
US20040132720A1,Cc1cc([N+](=O)[O-])ccc1-n1ccnc1>>Cc1cc(N)ccc1-n1ccnc1,[Pd],,,C1=CCCCC1,,test
US06054591,C[Si](C)(C)CCOC(=O)CCCCCCCCC(=O)[O-].Cc1cc(C)cc(Sc2c(C(C)C)nc(C)n2COCCO)c1>>Cc1cc(C)cc(Sc2c(C(C)C)nc(C)n2COCCOC(=O)CCCCCCCCC(=O)OCC[Si](C)(C)C)c1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04321381,CCCN1C[C@H](C(=O)OC)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21>>CCCN1C[C@H](CO)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21,,CO,O,[BH4-].[Na+],,test
US20160166560A1,COc1ccc(N2CCC(N(C)C(=O)n3cnc(-c4cccc(NS(C)(=O)=O)c4)c3)CC2)cc1>>CN(C(=O)n1cnc(-c2cccc(NS(C)(=O)=O)c2)c1)C1CCN(c2ccc(O)cc2)CC1,,ClCCl,,BrB(Br)Br,,test
US20040006834A1,COc1cc2c(cc1OC)N(c1ccc([N+](=O)[O-])cc1)CC2.Cl>>COc1cc2c(cc1OC)N(c1ccc(N)cc1)CC2.Cl,[Pd],CCO,O,[H][H],,test
US04144343,CC(=O)OC(C)=O.N[NH+]([O-])C(=O)c1cccnc1>>CC(=O)[N+](N)([O-])C(=O)c1cccnc1,,CCOCC,,CC(=O)O,,test
US20030232869A1,COC(=O)c1cc2nc[nH]c2c(F)c1Nc1ccc(Br)cc1C.NN>>Cc1cc(Br)ccc1Nc1c(C(=O)NN)cc2[nH]cnc2c1F,,CCO,,O,,test
US20150126490A1,COC(=O)c1ccc(-c2cccnc2N)cc1F.O=C1CCC(=O)N1Br>>COC(=O)c1ccc(-c2cc(Br)cnc2N)cc1F,,CC#N,,,,test
US20030199440A1,CCOC(=O)C1(N)CCC1.O=S(=O)(Cl)c1ccc2c(Cl)cnc(Cl)c2c1>>CCOC(=O)C1(NS(=O)(=O)c2ccc3c(Cl)cnc(Cl)c3c2)CCC1,,ClCCl,,CCN(CC)CC,Cl,test
US20040106667A1,CS(=O)(=O)c1ccccc1S(=O)(=O)Cl.C[Si](C)(C)CCOCn1nc(CCc2ccccc2)c2cc(N)ccc21>>C[Si](C)(C)CCOCn1nc(CCc2ccccc2)c2cc(NS(=O)(=O)c3ccccc3S(C)(=O)=O)ccc21,,O,c1ccncc1,,,test
US20150051199A1,CC[C@@H](NCC(C)(C)C(=O)O)c1ccc(Cl)c(C(=O)c2cccnc2)c1F.[NH4+]>>CC[C@@H](NCC(C)(C)C(N)=O)c1ccc(Cl)c(C(=O)c2cccnc2)c1F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04990495,CC(C)(C)C1OC2CCC=CCCC=CCCC2O1>>CC(C)(C)COC1CCC=CCCC=CCCC1O,,Cc1ccccc1,,CC(C)C[AlH]CC(C)C,,test
US20110092505A1,CC(C)(C)OC(=O)N1CCNCC1.CCOC(=O)c1ccc(Cl)nc1Cl>>CCOC(=O)c1ccc(Cl)nc1N1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20080269210A1,CC(=O)OCC(=O)Cl.CNCc1cc2nc(Cl)nc(N3CCOCC3)c2s1>>CC(=O)OCC(=O)N(C)Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1,,ClCCl,,CCN(CC)CC,,test
US20020049239A1,C[Sn](C)(C)C.O=[N+]([O-])c1cc(Br)c2c(c1)CCN2>>Cc1cc([N+](=O)[O-])cc2cc[nH]c12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,ClC(Cl)Cl,,test
US20100240669A1,COC(=O)c1ccc(Nc2ccc(CNC(=O)C3(NC(=O)c4cncnc4)CC3)nc2)c(C(F)(F)F)c1>>O=C(O)c1ccc(Nc2ccc(CNC(=O)C3(NC(=O)c4cncnc4)CC3)nc2)c(C(F)(F)F)c1,,[Na+],[OH-],CCO,Cl,test
US20110021351A1,CCOC(=O)CC1(Cl)NC(C)=CS1>>CC1=CSC(Cl)(CC(=O)O)N1,,CO,,[Na+].[OH-],,test
US20080070960A1,CCc1cc(-c2noc3ccccc23)c(OC)cc1OC>>CCc1cc(-c2noc3ccccc23)c(O)cc1O,,ClCCl,,BrB(Br)Br,,test
US20130102776A1,CCOc1ccc2c(c1CN1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1c[nH]c3ccccc13)C2=O>>CCOc1ccc2c(c1CN1CCNCC1)O/C(=C\c1c[nH]c3ccccc13)C2=O,,C1COCCO1,ClCCl,Cl,,test
US20130165433A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COc1ncc(Br)cc1NS(C)(=O)=O>>COc1ncc(B2OC(C)(C)C(C)(C)O2)cc1NS(C)(=O)=O,,Cc1ccccc1,,CC(=O)[O-].[K+],,test
US20060135554A1,CCOc1ccc(Cc2nc3cc(C#N)ccc3n2CC2CC2)cc1.O=CO>>CCOc1ccc(Cc2nc3cc(C=O)ccc3n2CC2CC2)cc1,[Ni],,,,,test
US20060089362A1,CCOC(=O)c1cc(Cl)n2nccc2n1>>CCOC(=O)c1ccn2nccc2n1,[Pd],CCO,CCOC(C)=O,CC(=O)[O-].[Na+],,test
US08293735B2,CC(C)(C)OC(=O)N1CCC(N2CCC2)C(C(N)=O)C1>>NC(=O)[C@@H]1CNCC[C@H]1N1CCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140213571A1,BrCBr.Oc1ccc(Cl)cc1-c1cc2c(F)cccc2[nH]1>>Fc1cccc2c1cc1n2COc2ccc(Cl)cc2-1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090099231A1,CC(C)(C)OC(=O)N1CCc2cc(N)ccc2C1.CSCC[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CSCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccc2c(c1)CCN(C(=O)OC(C)(C)C)C2,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04948809,O=S(=O)(NCCc1ccc(CCCO)cc1)c1ccc(Cl)cc1>>O=Cc1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20040121964A1,COC(=O)[C@@H]1CC[C@H](C#C[Si](C)(C)C)N1.O=C(Cl)CCl>>COC(=O)[C@@H]1CC[C@H](C#C[Si](C)(C)C)N1C(=O)CCl,,C1CCOC1,,CCN(CC)CC,,test
US20060089404A1,CC(C)C(C)(Oc1ccc(OCc2ccccc2)cc1)C(=O)[O-].CO>>CCC(C)(Oc1ccc(O)cc1)C(=O)OC,[Pd],,,,,test
US20100160323A1,COC(=O)c1cccc(C(=O)O)c1.NN>>NNC(=O)c1cccc(C(=O)O)c1,,CO,,O,,test
US20110150834A1,CC(=O)CC(C(=O)c1ccccc1)c1ccc(F)cc1.CCOC(=O)CN>>CCOC(=O)Cn1c(C)cc(-c2ccc(F)cc2)c1-c1ccccc1,,CCO,ClCCl,CCN(CC)CC,Cl,test
US20140142083A1,CC=O.COC(=O)c1cc(C(F)(F)F)cc(NC2CCN(C(=O)OC(C)(C)C)CC2)c1C>>CCN(c1cc(C(F)(F)F)cc(C(=O)OC)c1C)C1CCN(C(=O)OC(C)(C)C)CC1,,CC(=O)O,ClCCl,O=C([O-])O.[Na+],,test
US20150072969A1,CCOC(=O)CC1(c2ccc(OCc3cccc(-c4ccc(OCC5CCOCC5)cc4Cl)c3)cc2)COC1>>O=C(O)CC1(c2ccc(OCc3cccc(-c4ccc(OCC5CCOCC5)cc4Cl)c3)cc2)COC1,,C1CCOC1,CO,O,[Li+].[OH-],test
US06245761B1,CN(C)CCCCOCc1cc(Br)ccc1F>>CNCCCCOCc1cc(Br)ccc1F,,CC(Cl)Cl,,,,test
US20040180922A1,CCOC(=O)c1cc(C)nc(Cl)c1C#N.NC(N)=S>>CCOC(=O)c1cc(C)nc(S)c1C#N,,CCO,,,,test
US20070037809A1,Cc1cnc2sc(-c3ccccc3[N+](=O)[O-])nc2c1.O=C1CCC(=O)N1Br>>O=[N+]([O-])c1ccccc1-c1nc2cc(CBr)cnc2s1,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US04036971,CCOC(=N)c1ccc(S)cc1.Cc1nc[nH]c1CSCCN>>Cc1[nH]cnc1CSCCNC(=N)c1ccc(S)cc1,,CCO,,,,test
US20080085886A1,ClC(Cl)(Br)C(Cl)(Cl)Br.O=C(O)c1cncc(Br)c1>>O=C(O)c1cncc(Br)c1Br,,C1CCOC1,,O,CC(C)[N-]C(C)C.[Li+],test
US08940900B2,CCOC(=O)C(C)(C)Oc1cccc(N)c1.FC(F)(F)c1ccc(CCI)cc1>>CCOC(=O)C(C)(C)Oc1cccc(NCCc2ccc(C(F)(F)F)cc2)c1,,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20110319380A1,CCOC(=O)CNC(C)(C)CN>>CC1(C)CNC(=O)CN1,,CN(C)C=O,,,,test
US04348264,CC(C)OC(C)C.O=C(O)C(C(=O)O)c1ccccc1.O=S(Cl)Cl.OC(c1ccccc1)c1ccccc1>>CC(C)OC(C)C.O=C(Cl)C(C(=O)OC(c1ccccc1)c1ccccc1)c1ccccc1,,CC(C)OC(C)C,,CN(C)C=O,,test
US20050080262A1,C1COCCN1.COc1cc2c(=O)[nH]cnc2cc1OCCCCl>>COc1cc2c(=O)[nH]cnc2cc1OCCCN1CCOCC1,,CO,,,,test
US20080015208A1,CC(=O)OC(C)=O.NCC1CCCc2cc(NS(=O)(=O)c3cccc(F)c3)ccc21>>CC(=O)NCC1CCCc2cc(NS(=O)(=O)c3cccc(F)c3)ccc21,,O,c1ccncc1,,,test
US20160015690A1,Cc1cc2nc(N3CCOC(c4ccc5c(cnn5C)c4)C3)sc2c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O.Cc1cc2nc(N3CCO[C@@H](c4ccc5c(cnn5C)c4)C3)sc2c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O>>Cc1cc2nc(N3CCO[C@@H](c4ccc5c(cnn5C)c4)C3)sc2c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O.Cc1cc2nc(N3CCO[C@H](c4ccc5c(cnn5C)c4)C3)sc2c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O,,CC(=O)O,,,,test
US04680303,Cc1cccc(C(CCCO)OC(CCCO)c2cccc(C)n2)n1.O=S(Cl)Cl>>Cc1cccc(C(CCCCl)OC(CCCCl)c2cccc(C)n2)n1,,O,,ClC(Cl)Cl,,test
US20110104075A1,C#CCOc1cc(C=O)ccc1OCCBr>>C#CCOc1cc(CO)ccc1OCCBr,,C1CCOC1,CO,[BH4-].[Na+],,test
US20110034433A1,C=CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)NC1c1ccc(C#N)cc1SC>>CSc1cc(C#N)ccc1C1NC(=O)N(c2cccc(C(F)(F)F)c2)C(C)=C1C(=O)O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,C1COCCN1,,test
US03996216,N[C@@H](C(=O)O)c1ccccc1.O=CO>>O=CNC(C(=O)O)c1ccccc1,,O=CO,,CC(=O)OC(C)=O,,test
US20120136013A1,CC(C)Cn1c(=O)n(C)c(=O)c2c[nH]cc21.Fc1cccc(-c2ccc(CCl)cc2)n1>>CC(C)Cn1c(=O)n(C)c(=O)c2cn(Cc3ccc(-c4cccc(F)n4)cc3)cc21,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110124665A1,COC(=O)CCc1cccc(Nc2ncnc3oc(-c4ccccc4)c(-c4ccc(OC)cc4)c23)c1>>COc1ccc(-c2c(-c3ccccc3)oc3ncnc(Nc4cccc(CCC(=O)O)c4)c23)cc1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20160199875A1,Nc1ccc(OCCCCCCCCCCCCBr)cc1[N+](=O)[O-].O=CO>>BrCCCCCCCCCCCCOc1ccc2[nH]cnc2c1,[Fe],CC(C)O,,[Cl-].[NH4+],,test
US20070173487A1,Brc1ccc2occc2c1.O=c1ccocc1>>OC1(c2ccc3occc3c2)CCOCC1,,C1CCOC1,,II,,test
US20050032786A1,CN(C)CCS.N#Cc1cccc(Cl)n1>>CN(C)CCSc1cccc(C#N)n1,,C1CCOC1,,[H-].[Na+],,test
US20120040942A1,C[Mg]Br.Cc1nc2ncccc2cc1C(=O)NCc1ccc(C(C)(C)C)cc1>>Cc1nc2ncccc2c(C)c1C(=O)NCc1ccc(C(C)(C)C)cc1,,C1CCOC1,,,,test
US20120196851A1,COC(=O)[C@@H]1CC[C@@H](CNCCc2ccccc2[N+](=O)[O-])CC1>>COC(=O)[C@@H]1CC[C@@H](CNCCc2ccccc2N)CC1,[Pd],CO,,CC(=O)O,[H][H],test
US04543361,O=S(=O)(O)O.OC(c1ccc2c(c1)OCO2)C1CCC(CCc2ccccc2)N1>>O=S(=O)(O)O.OC(c1ccc2c(c1)OCO2)C1CCC(CCc2ccccc2)N1,,CCO,,CC(=O)O,,test
US20110166123A1,CCOC(=O)C(=CN[C@H](CO)C(C)C)C(=O)c1nc(Cl)ccc1Cl>>CCOC(=O)c1cn(C(CO)C(C)C)c2ccc(Cl)nc2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070004758A1,NN.O=c1cc(O)cc[nH]1>>NNc1cc[nH]c(=O)c1,,CCOCCO,,,,test
US05506190,CNC.O=C1C2=C(CCCC2)C(=O)N1c1cc(OC2CCCC2)c(Cl)cc1F>>CN(C)C(=O)C1=C(C(=O)Nc2cc(OC3CCCC3)c(Cl)cc2F)CCCC1,,ClC(Cl)(Cl)Cl,,,,test
US20040014754A1,NCCCCn1c(-c2ccccc2)nc2c(N)nc3ccccc3c21.S=C=Nc1cccnc1>>Nc1nc2ccccc2c2c1nc(-c1ccccc1)n2CCCCNC(=S)Nc1cccnc1,,ClC(Cl)Cl,c1ccncc1,,,test
US20110130398A1,CC(=O)OCC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C#N)cc2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12.OO>>NC(=O)c1ccc(NC(=O)C2CC3(CN2)C(=O)Nc2ccccc23)cc1,,CS(C)=O,,[Na+].[OH-],,test
US05919793,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.CCOc1cc(C=O)ccc1C#CC1(O)CN2CCC1CC2>>CCOC(=O)C=Cc1ccc(C#CC2(O)CN3CCC2CC3)c(OCC)c1,,Cc1ccccc1,,,,test
US20030162806A1,CC(C)C(=O)Cl.Cc1nc(N)c2nc(C)n(CCCN)c2c1C>>Cc1nc(N)c2nc(C)n(CCCNC(=O)C(C)C)c2c1C,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20100239525A1,COCCN.CS(=O)(=O)OCCc1ccc(Nc2ncc3c(n2)-c2ccccc2C(c2ccccc2C(F)(F)F)C3)cc1>>COCCNCCc1ccc(Nc2ncc3c(n2)-c2ccccc2C(c2ccccc2C(F)(F)F)C3)cc1,,CCN(CC)CC,,,,test
US20100317693A1,CC(C)(C)OC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)O.CI>>Cn1cc(C[C@@H](NC(=O)OC(C)(C)C)C(=O)O)c2ccccc21,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20120308588A1,CCOC(=O)[C@H](O)[C@@H](Cc1ccccc1C(F)(F)F)NC(=O)CCCc1ccccc1C(=O)O>>O=C(CCCc1ccccc1C(=O)O)N[C@H](Cc1ccccc1C(F)(F)F)[C@@H](O)C(=O)O,,CC(=O)O,,C1CCOC1,[Na+].[OH-],test
US20110086834A1,COCCO.O=[N+]([O-])c1cc(I)ccc1F>>COCCOc1ccc(I)cc1[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],,test
US20060173199A1,C=CCOC(C(=O)OCC)=C(O)CC>>C=CCOC(CO)C(O)C=C,,C1CCOC1,CCOC(C)=O,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20110015200A1,CS(=O)(=O)Cl.O=C1CC[C@@H](CN(CCO)Cc2ccccc2)N1>>CS(=O)(=O)OCCN(Cc1ccccc1)C[C@@H]1CCC(=O)N1,,CCO,ClCCl,,,test
US04472381,O=P(O)(CCc1ccccc1)CCc1ccccc1.O=S(=O)(Cl)Cl>>O=P(Cl)(CCc1ccccc1)CCc1ccccc1,,ClC(Cl)(Cl)Cl,,,,test
US20080293776A1,CS(=O)[O-].ClCc1ccccc1CCl>>CS(=O)(=O)Cc1ccccc1CCl,,CN(C)C=O,,CCOC(C)=O,,test
US05037827,ClCc1ccccn1.O=C1CNC(=O)N1>>O=C1CNC(=O)N1Cc1ccccn1,,CN(C)C=O,,,,test
US04772633,COc1ccc(C(C)(C=C(Br)Br)CCCc2cccc(Oc3ccccc3)n2)cc1>>CC(C=C(Br)Br)(CCCc1cccc(Oc2ccccc2)n1)c1ccc(O)cc1,,CC#N,,C[Si](C)(C)Cl,[I-].[Na+],test
US20070219212A1,CCC[C@]1(CC(=O)OC)OCCc2c1[nH]c1c(C)c(OCc3nnc(C)s3)cc(C#N)c21>>CCC[C@]1(CC(=O)O)OCCc2c1[nH]c1c(C)c(OCc3nnc(C)s3)cc(C#N)c21,,O,,CCO,[Na+].[OH-],test
US20060019997A1,CS(=O)(=O)c1nnc(-c2ccncc2)n1C1CC1.OCc1cn(-c2cccc(Cl)c2)nn1>>Clc1cccc(-n2cc(COc3nnc(-c4ccncc4)n3C3CC3)nn2)c1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20160060233A1,COc1ccc(N)c(C)c1.O=C(N=C=S)c1ccccc1>>COc1ccc(NC(=S)NC(=O)c2ccccc2)c(C)c1,,CC(C)=O,,,,test
US06562827B1,COC(=O)c1cccnc1Cl.c1cc(N2CCNCC2)ccn1>>COC(=O)c1cccnc1N1CCN(c2ccncc2)CC1,,CN(C)C=O,,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US20080275043A1,CC1(N)CCC2(CC1)OCCO2.O=CCCC(=O)N1CCOC1=O>>CC1(N2CCCC2=O)CCC2(CC1)OCCO2,,ClCCCl,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20030004181A1,CNc1ccc(C)nc1N.N#Cc1ccc(OCC(=O)O)cc1>>Cc1ccc2c(n1)nc(COc1ccc(C#N)cc1)n2C,,C1CCOC1,,,,test
US20060111375A1,COc1cc2c(Cl)ccnc2cc1OCc1ccccc1.Cc1cc(O)c(-c2cccnc2)nc1C>>COc1cc2c(Oc3cc(C)c(C)nc3-c3cccnc3)ccnc2cc1OCc1ccccc1,CN(C)c1ccncc1,Clc1ccccc1Cl,,O,,test
US20100112090A1,COc1cc(Cl)c(-n2c(=O)[nH]c3c(OC)nc(CC(=O)O)nc32)cc1OCc1c(F)cccc1OC>>COc1cc(Cl)c(-n2c(=O)[nH]c3c(OC)nc(CCO)nc32)cc1OCc1c(F)cccc1OC,,C1CCOC1,,B,Cl,test
US20150183788A1,CC#CCn1c(N2CCC[C@@H](N)C2)nc2c1c(=O)n(Cc1nc3cc(F)ccc3s1)c(=O)n2C.Cl>>CC#CCn1c(N2CCC[C@@H](N)C2)nc2c1c(=O)n(Cc1nc3cc(F)ccc3s1)c(=O)n2C.Cl,,ClCCl,,,,test
US20030073707A1,CCOC(=O)C(=O)OCC.Nc1ccc(F)cc1S>>CCOC(=O)c1nc2ccc(F)cc2s1,,CCO,,Cl,O,test
US04358406,CC(=O)O.CC(=O)O.CC(=O)O.C[C@H](CCCC(O)(C(F)(F)F)C(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@@]21C>>CC(=O)O[C@@H]1CC2=CC=C3[C@@H]4CC[C@H]([C@H](C)CCCC(OC(C)=O)(C(F)(F)F)C(F)(F)F)[C@@]4(C)CC[C@@H]3[C@@]2(C)[C@@H](OC(C)=O)C1,,ClC(Cl)(Cl)Cl,,O=C1CCC(=O)N1Br,,test
US20050049245A1,CNCC(O)C1=CNC2C=CC=CC12.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CCl)sc21>>CN(Cc1cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c2s1)CC(O)c1c[nH]c2ccccc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20050261350A1,CCC1(CC)C(=O)N(C)c2cc([N+](=O)[O-])c(NC(=O)c3ccc(OC)cc3)cc21>>CCC1(CC)C(=O)N(C)c2cc3nc(-c4ccc(OC)cc4)[nH]c3cc21,[Ni],,,,,test
US20150065495A1,Nc1cc(Cl)ccc1O.O=S(=O)(c1ccc2[nH]c(Cl)nc2c1)N1CCOCC1>>O=S(=O)(c1ccc2[nH]c(Nc3cc(Cl)ccc3O)nc2c1)N1CCOCC1,,C1CCOC1,,Cl,,test
US20120225854A1,CC(C)(C)OC(=O)NCC(=O)O.CCOC(=O)[C@@H](N)Cc1ccnc(OC)c1>>CCOC(=O)[C@H](Cc1ccnc(OC)c1)NC(=O)CNC(=O)OC(C)(C)C,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160046618A1,CC(C)(C)OC(=O)C[C@](CF)(N[S@](=O)C(C)(C)C)c1cccc(F)c1F>>CC(C)(C)[S@@](=O)N[C@@](CF)(CCO)c1cccc(F)c1F,,C1CCOC1,,CO,[BH4-].[Li+],test
US05500442,CC1(C)Oc2ccc(I)cc2[C@@H](N2Cc3ccccc3C2=O)[C@@H]1O.CCCC[Sn](CCCC)(CCCC)c1c(OC(C)C)c(=O)c1=O>>CC(C)Oc1c(-c2ccc3c(c2)[C@@H](N2Cc4ccccc4C2=O)[C@H](O)C(C)(C)O3)c(=O)c1=O,Cl[Cu],CC#N,CN(C)C=O,,,test
US20030181726A1,CC(=O)Oc1ccc(OCc2ccccc2)c([N+](=O)[O-])c1.CO>>O=[N+]([O-])c1cc(OC[C@@H]2CO2)ccc1OCc1ccccc1,,CO,,C[O-].[Na+],,test
US20100256092A1,CCO.O=C(O)CCC1OB(O)c2cc(Oc3cccc(OCc4ccccc4)c3)ccc21>>CCOC(=O)CCC1OB(O)c2cc(Oc3cccc(OCc4ccccc4)c3)ccc21,O=S(=O)(O)O,,,,,test
US20070043040A1,O=S(=O)(O)c1cccc2cnccc12.O=S(Cl)Cl>>Cl.O=S(=O)(Cl)c1cccc2cnccc12,,ClCCl,,CN(C)C=O,,test
US03954789,Cn1c(C=O)cnc1[N+](=O)[O-].NNC(N)=S>>Cn1c(C=NNC(N)=S)cnc1[N+](=O)[O-],,CO,O,,,test
US20120289501A1,O=C(NC1CC(COC(=O)c2ccccc2)C1)OCc1ccccc1>>O=C(N[C@@H]1C[C@H](CO)C1)OCc1ccccc1,,C1CCOC1,,[Li+].[OH-],,test
US20030114666A1,CONC(=O)c1cc(F)c(F)cc1N.O=C(Cl)Cl>>COn1c(=O)[nH]c2cc(F)c(F)cc2c1=O,,C1COCCO1,,Cc1ccccc1,O,test
US20030229051A1,C/C=C/C(=O)O.Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1>>C/C=C/C(=O)Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1,,c1ccncc1,,CCN=C=NCCCN(C)C,Cl,test
US20150266857A1,NC(=O)CBr.O=c1[nH]c2ccc(-c3cn(S(=O)(=O)c4ccccc4)c4cc(F)ccc34)cc2o1>>NC(=O)Cn1c(=O)oc2cc(-c3cn(S(=O)(=O)c4ccccc4)c4cc(F)ccc34)ccc21,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20160102071A1,CC#C[C@@H](CC(=O)OCC)c1ccc(O)nc1.Cc1ccccc1-c1csc2ccc(CBr)cc12>>CC#C[C@@H](CC(=O)OCC)c1ccc(OCc2ccc3scc(-c4ccccc4C)c3c2)nc1,,Cc1ccccc1,,O,,test
US20150087639A1,CC(C)(C)OC(=O)Nc1cc(N)ccc1F.ClCCOCCCl>>CC(C)(C)OC(=O)Nc1cc(N2CCOCC2)ccc1F,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20160039842A1,COc1cc2c(cc1-c1c(C)noc1C)nc(C=O)c1oc(=O)n(Cc3ccccc3)c12>>COc1cc2c(cc1-c1c(C)noc1C)nc(CO)c1oc(=O)n(Cc3ccccc3)c12,,CO,,[BH4-].[Na+],,test
US20160166548A1,C#CCCC(C)(C)O.C[Si](C)(C)C#CBr>>CC(C)(O)CCC#CC#C[Si](C)(C)C,[Cu]I,C1CCNCC1,,,,test
US04048198,COC(=O)CCCCCCCC1CCC(C(OC)OC)O1>>COC(=O)CCCCCCCC1CCC(C=O)O1,,CC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20150051160A1,C=CCOC(=O)[C@H](Cc1ccc(OC(=O)NCC[C@H](NC(=O)OC(C)(C)C)C(=O)NCC(=O)N[C@@H](CSC(c2ccccc2)(c2ccccc2)c2ccccc2)C(N)=O)cc1)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OC(=O)NCC[C@H](NC(=O)OC(C)(C)C)C(=O)NCC(=O)N[C@@H](CSC(c2ccccc2)(c2ccccc2)c2ccccc2)C(N)=O)cc1)C(=O)O,,C1CCOC1,O,CCN(CC)CC,O=CO,test
US20130053365A1,COC(=O)c1cc(F)cc(F)c1C(=O)C(c1ncnn1C)C(C[N+](=O)[O-])c1ccc(F)cc1.NN>>Cn1ncnc1C(c1n[nH]c(=O)c2cc(F)cc(F)c12)C(C[N+](=O)[O-])c1ccc(F)cc1,,CO,,O,,test
US20120214837A1,CCc1nc(O)cc2cc(OC)c(OC)cc12.ClCc1ccc2oc3ccccc3c2c1>>CCc1nc(O)c(Cc2ccc3oc4ccccc4c3c2)c2cc(OC)c(OC)cc12,,Cc1ccccc1,ClCCl,[K+].[OH-],,test
US04916149,NNc1ccc(C(F)(F)F)cc1[N+](=O)[O-].O=CO>>NN(C=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-],,O,,,,test
US05134151,CCCCCCCCCCCCCCCN=C=O.OCCSCCO>>CCCCCCCCCCCCCCCCCN=C=O,,OCCOCCO,,,,test
US20150133511A1,CCOC(=O)c1nnn(C[Si](C)(C)C)c1-c1ccc(Br)cc1>>CCOC(=O)c1nnn(C)c1-c1ccc(Br)cc1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20160168165A1,NCCCN1C(=O)S/C(=C\c2ccc(Sc3nc4ccccc4[nH]3)o2)C1=O.O=C=Nc1ccccc1>>O=C(NCCCN1C(=O)S/C(=C\c2ccc(Sc3nc4ccccc4[nH]3)o2)C1=O)Nc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20070004700A1,CC(=O)OC(C)=O.CC[Si](CC)(CC)O[C@H](C)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(S/C=C\c3scnc3CO)[C@H](C)[C@H]12>>CC[Si](CC)(CC)O[C@H](C)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(S/C=C\c3scnc3COC(C)=O)[C@H](C)[C@H]12,,C1CCOC1,,CCOC(C)=O,c1ccncc1,test
US04032661,CCC1CCCCC1(O)CC.CCCCCCS>>CCCCCCSC1(CC)CCCCC1CC,,O,,O=S(=O)(O)O,,test
US05639780,BrBr.COc1ccc2c(c1)c(C1(CCO)CC1)c(C)n2Cc1ccc(Br)cc1>>COc1ccc2c(c1)c(C1(CCBr)CC1)c(C)n2Cc1ccc(Br)cc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04906633,CNCCN.Nc1nc(N)c(C(=O)n2ccnc2)nc1Cl>>CNCCNC(=O)c1nc(Cl)c(N)nc1N,,C1CCOC1,,,,test
US20130131035A1,Clc1ccc(-c2nnc3cnccn23)cc1>>Clc1ccc(-c2nnc3n2CCNC3)cc1,[Pd],CCO,,,,test
US20030232828A1,BrCc1ccccc1.Sc1c[nH]c2ccccc12>>c1ccc(CSc2c[nH]c3ccccc23)cc1,,C1COCCO1,,O,[H-].[Na+],test
US20100063066A1,CC(C)(C)OC(=O)n1nc(C#CCO[Si](C)(C)C(C)(C)C)c2c([N+](=O)[O-])cccc21>>CC(C)(C)OC(=O)n1nc(CCCO[Si](C)(C)C(C)(C)C)c2c(N)cccc21,[Pd],CCOC(C)=O,CO,,,test
US20040127570A1,CO.COc1ccc2cc(C(=O)O)ccc2c1>>COC(=O)c1ccc2cc(OC)ccc2c1,,CO,c1ccccc1,C[Si](C)(C)C=[N+]=[N-],,test
US20100210647A1,N=C(NO)C1CCCC1.O=C(O)CC1CSC(c2cc3cccc(NC4CCCC4)c3[nH]2)=N1>>c1cc(NC2CCCC2)c2[nH]c(C3=N[C@H](Cc4nc(C5CCCC5)no4)CS3)cc2c1,,CN(C)C=O,,O,,test
US05763437,C[C@H](NC(=O)c1cccc([N+](=O)[O-])c1)C(=O)OCc1ccccc1>>C[C@H](NC(=O)c1cccc(N)c1)C(=O)OCc1ccccc1,[Fe],CCO,,[Cl-].[NH4+],,test
US06498172B1,COC(=O)c1ccc(CCCNCCCc2cccc(Cl)c2)s1.O=S(=O)(Cl)C1CC1>>COC(=O)c1ccc(CCCN(CCCc2cccc(Cl)c2)S(=O)(=O)C2CC2)s1,,ClCCl,,CCN(CC)CC,,test
US05877193,Cc1ccc(S(=O)(=O)NC(N)=S)cc1.O=C(CBr)c1cc(O)c(O)c([N+](=O)[O-])c1>>Cc1ccc(S(=O)(=O)Nc2nc(-c3cc(O)c(O)c([N+](=O)[O-])c3)cs2)cc1,,CCO,,,,test
US06057358,COc1ccc(CCN(C)CCO)cc1OC.O=[N+]([O-])c1ccc(Cl)cc1[N+](=O)[O-]>>COc1ccc(CCN(C)CCOc2ccc([N+](=O)[O-])c([N+](=O)[O-])c2)cc1OC.Cl,,CS(C)=O,,[H-].[Na+],,test
US20160159752A1,COC(=O)N[C@H](C(=O)Nc1cccc(F)c1CC[C@H]1CN(C(=O)OC(C)(C)C)CCN1S(=O)(=O)c1ccccc1)[C@@H](c1ccc(Cl)cc1)c1ccc(OC)nc1>>COC(=O)N[C@H](C(=O)Nc1cccc(F)c1CC[C@H]1CNCCN1S(=O)(=O)c1ccccc1)[C@@H](c1ccc(Cl)cc1)c1ccc(OC)nc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06582351B1,CC(C)(N)CO.O=[N+]([O-])c1cc(C(F)(F)F)cnc1Cl>>CC(C)(CO)Nc1ncc(C(F)(F)F)cc1[N+](=O)[O-],,CCOC(C)=O,CN(C)C=O,,,test
US04539321,CC(=O)OC(C)=O.Nc1cc(-c2ccncn2)c[nH]c1=O>>CC(=O)Nc1cc(-c2ccncn2)c[nH]c1=O,,c1ccncc1,,,,test
US20090299072A1,COC(=O)C(CC1CCC1)c1ccc([N+](=O)[O-])c(OCC(F)(F)F)c1>>COC(=O)C(CC1CCC1)c1ccc(N)c(OCC(F)(F)F)c1,[Pd],CCO,,,,test
US20150183728A1,CC(=O)OC(C)=O.O=C(Oc1ccccc1C(=O)O)c1ccccc1O>>CC(=O)Oc1ccccc1C(=O)Oc1ccccc1C(=O)O,O=S(=O)(O)O,,,,,test
US20040157741A1,Cc1ccc(C(=N)N)cc1F.O=S(=O)(Cl)c1ccc(F)c(Cl)c1>>Cc1ccc(C(=N)NS(=O)(=O)c2ccc(F)c(Cl)c2)cc1F,,C1CCOC1,,CN1CCOCC1,Cl,test
US20090036448A1,Cc1nc(N[C@@H]2CC[C@H](CN)CC2)cc(N(C)C)n1.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(O)C(F)(F)F>>Cc1nc(N[C@@H]2CC[C@H](CNC(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC2)cc(N(C)C)n1.O=C(O)C(F)(F)F,,CN(C)C=O,CS(C)=O,c1ccncc1,,test
US20100022585A1,CC(C)(C)OC(=O)NC(C(=O)O)c1ccsc1>>CC(C)(C)OC(=O)NC(CO)c1ccsc1,,C1CCOC1,,B,,test
US20040214822A1,Cl[Mg]Cc1ccccc1.N#CC1(N2CCCC2)CCC2(CC1)OCCO2>>c1ccc(CC2(N3CCCC3)CCC3(CC2)OCCO3)cc1,,C1CCOC1,C1CCOC1,[Cl-].[NH4+],,test
US04474776,CCOP(=O)(Cl)OCC.Cc1ccc(O)c2cc3ccccc3cc12>>CCOP(=O)(OCC)Oc1ccc(C)c2cc3ccccc3cc12,,Cc1ccccc1,,CCN(CC)CC,CCOC(C)=O,test
US20010034343A1,CCOCCn1c(O)nc2ccccc21.O=P(Cl)(Cl)Cl>>CCOCCn1c(Cl)nc2ccccc21,,CCOC(C)=O,,[Na+].[OH-],,test
US06498251B1,O=C1CCCCN1Cc1ccccc1.c1ccc2c(c1)CCNC2>>c1ccc(CN2CCC(N3CCc4ccccc4C3)CC2)cc1,,CC(Cl)Cl,,CC(=O)O,[Na+].[OH-],test
US20150126485A1,O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(Cl)c(Br)c1.O[C@H]1CNC[C@@H]1O>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2C[C@H](O)[C@@H](O)C2)c(Br)c1,,CC(C)O,,CCN(C(C)C)C(C)C,Cl,test
US04914226,CC(C)(C)OC(=O)OC(C)(C)C.NCCCCl>>CC(C)(C)OC(=O)NCCCCl,,C1COCCO1,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20120196833A1,CC(C)[Si](C#Cc1cc(N)ccc1OCc1cccc(F)c1)(C(C)C)C(C)C.Clc1ncnc2ccc(I)cc12>>CC(C)[Si](C#Cc1cc(Nc2ncnc3ccc(I)cc23)ccc1OCc1cccc(F)c1)(C(C)C)C(C)C,,CC(C)O,,,,test
US20050032838A1,CSc1ccc(O)cc1C.O=C(N[C@@H]1CC[C@@H](O)CC1)c1cc(F)cnc1Cl>>CSc1ccc(Oc2ncc(F)cc2C(=O)N[C@@H]2CC[C@@H](O)CC2)cc1C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130053345A1,CC(C)(C)OC(=O)N1CC=C(c2ccc3nc(OC4CCNCC4)sc3c2)CC1.C[Si](C)(C)CCOC(=O)ON1C(=O)CCC1=O>>CC(C)(C)OC(=O)N1CC=C(c2ccc3nc(OC4CCN(C(=O)OCC[Si](C)(C)C)CC4)sc3c2)CC1,,C1COCCO1,ClCCl,CCN(CC)CC,,test
US03993683,CC(c1ccc(-c2ccccc2F)cc1)S(=O)CC(=O)O.CO>>COC(=O)CS(=O)C(C)c1ccc(-c2ccccc2F)cc1,,c1ccccc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20100029611A1,Cc1cc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)cc(C)c1OCc1ccccc1>>Cc1cc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)cc(C)c1O,,ClCCl,,BrB(Br)Br,,test
US20080045526A1,Cc1ccc2c(n1)COC2=O.O=[Se]=O>>O=Cc1ccc2c(n1)COC2=O,,C1COCCO1,,,,test
US20080269284A1,CC(=O)N[C@@H]1C[C@H](C2CC2)N(C(=O)OC(C)C)c2ccc(C(F)(F)F)cc21>>CC(C)OC(=O)N1c2ccc(C(F)(F)F)cc2[C@H](N)C[C@@H]1C1CC1,,CCO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20150038574A1,CC(C)Oc1cccc(N)c1.CC1=C(C=O)C(C)(C)CCC1>>CC1=C(CNc2cccc(OC(C)C)c2)C(C)(C)CCC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US04772310,N#CCC(=O)Nc1ccnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl.O=[N+]([O-])O>>N#CCC(=O)Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20050176706A1,BrBr.Cc1cc(N)cc(C)n1>>Cc1cc(N)c(Br)c(C)n1,,CC(=O)O,,[Na+].[OH-],,test
US05929097,COC(=O)c1cc(C)cc(C)c1N(Cc1ccccc1)S(=O)(=O)c1ccc(F)cc1.OCc1ccccc1>>Cc1cc(C)c(N(Cc2ccccc2)S(=O)(=O)c2ccc(OCc3ccccc3)cc2)c(C(=O)O)c1,,CN(C)C=O,,[H-].[Na+],,test
US20120283297A1,CC(C)Oc1ccc(C(=O)O)cc1C#N.CCOC(=O)CCCn1ncc2cc(C(=N)NO)c(CC)cc21>>CCOC(=O)CCCn1ncc2cc(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)c(CC)cc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040044203A1,Cc1cc(Br)cc2[nH]c(-c3c(N[C@H](CO)Cc4ccccc4)cc[nH]c3=O)nc12.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1cc(Br)cc2[nH]c(-c3c(N[C@H](COC(c4ccccc4)(c4ccccc4)c4ccccc4)Cc4ccccc4)cc[nH]c3=O)nc12,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04250176,C=C(C)n1c(=O)[nH]c2ccccc21.ClCCCCCCl>>C=C(C)n1c(=O)n(CCCCCCl)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20140315801A1,COCCN(Cc1ccc(-c2cc3nccc(Oc4ccc(NC(=O)NC5CC5)cc4F)c3s2)nc1)C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C>>COCCN(Cc1ccc(-c2cc3nccc(Oc4ccc(NC(=O)NC5CC5)cc4F)c3s2)nc1)C(=O)[C@@H](N)C(C)(C)C,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20120253042A1,CC(C)O.CC(O)c1ccccc1.CCCCCCOC(=O)CCCCC>>CCCCCC(=O)OC(C)C.CCCCCCOC(=O)CCCCC,,CC(C)O,,CC(C)=O,,test
US05182303,CCOC(=O)NN.O=C1c2ccc(F)cc2CC1c1ccc(F)cc1>>CCOC(=O)NN=C1c2ccc(F)cc2CC1c1ccc(F)cc1,O=S(=O)(O)O,CO,,,,test
US20110076292A1,CC(C)n1ncnc1-c1cn2c(n1)-c1cnc(OS(=O)(=O)C(F)(F)F)cc1OCC2.CN>>CNc1cc2c(cn1)-c1nc(-c3ncnn3C(C)C)cn1CCO2,,CN1CCCC1=O,O,C1CCOC1,,test
US20080194653A1,CC(C)(C)OC(=O)NCCC1(c2ccccc2)SC(NC(=O)C(C)(C)C)=NN1C(=O)C(C)(C)C.O=C(O)C(F)(F)F>>CC(C)(C)C(=O)NC1=NN(C(=O)C(C)(C)C)C(CCN)(c2ccccc2)S1.O=C([O-])C(F)(F)F,,ClCCl,,,,test
US20070161787A1,CC(=O)OC[C@H]1O[C@@H](c2cc(Cc3cc4ccccc4s3)ccc2O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.CC(C)O>>CC(=O)OC[C@H]1O[C@@H](c2cc(Cc3cc4ccccc4s3)ccc2OC(C)C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140080860A1,CC(=O)OC12CCN(C(C)=O)C1N(C(C)=O)c1ccc(O)cc12.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(=O)OC12CCN(C(C)=O)C1N(C(C)=O)c1ccc(OC(=O)Oc3ccc([N+](=O)[O-])cc3)cc12,,C1CCOC1,,CN1CCOCC1,,test
US20080039494A1,C[C@@H](O[C@H]1CCc2cccnc2[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(OO)c1cccc(Cl)c1>>C[C@@H](O[C@H]1CCc2ccc[n+]([O-])c2[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,ClCCl,,[Na+].[OH-],,test
US20080234237A1,CC(C)N.O=C(CCl)N1CCCc2cc(Br)ccc21>>CC(C)NCCN1CCCc2cc(Br)ccc21,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20100076046A1,CC(C)(C)OC(=O)N(Cc1ccccc1)S(=O)(=O)CCCCl.CN(C)CCN>>CNCCN(C)CCCS(=O)(=O)N(Cc1ccccc1)C(=O)OC(C)(C)C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090042876A1,CCC(=O)O.O=c1[nH]c2ccc(S(=O)(=O)NC3CC4CCC(C3)N4Cc3ccccc3)cc2c2cc[nH]c12>>CCC(=O)[O-].O=c1[nH]c2ccc(S(=O)(=O)NC3CC4CCC(C3)N4)cc2c2cc[nH]c12,[Pd],CCO,,,,test
US20040127574A1,CCOC(=O)C(Cc1cccc(OC(F)(F)C(F)F)c1)C(O)c1ccc(Oc2ccccc2)cc1>>O=C(O)C(Cc1cccc(OC(F)(F)C(F)F)c1)C(O)c1ccc(Oc2ccccc2)cc1,,CO,,Cl,[Na+].[OH-],test
US20150291595A1,CN(C)C1CCNCC1.Fc1cc(Br)ccn1>>CN(C)C1CCN(c2cc(Br)ccn2)CC1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20140315888A1,CN(C(=O)OC(C)(C)C)C1CN(c2nc3ncc(Cl)cc3n3nnnc23)C1>>CNC1CN(c2nc3ncc(Cl)cc3n3nnnc23)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050171130A1,CC#CCO.CC(Oc1cc(Cl)ncn1)C1(C)CC1>>CC#CCOc1cc(OC(C)C2(C)CC2)ncn1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US06121285,CCOC(=O)C1([C@@H]2CN(C(=O)OCc3ccccc3)C[C@H]2O[Si](C)(C)C(C)(C)C)CC1>>CCOC(=O)C1([C@@H]2CN(C(=O)OCc3ccccc3)C[C@H]2O)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150105373A1,CCC(=NO)c1ccc(Cl)cc1>>CCC(N)c1ccc(Cl)cc1,,C1CCOC1,,Cl,,test
US20050261177A1,CCOC(=O)c1ccc(N2CCC(=O)/C(=C/N(C)C)C2)cc1.NN.NNc1ccccc1>>NNC(=O)c1ccc(N2CCc3nn(-c4ccccc4)cc3C2)cc1,,CCO,,O,,test
US20080306046A1,CC(C)(C)OC(=O)N1CCC(O)CC1.Oc1cccc(Cl)n1>>CC(C)(C)OC(=O)N1CCC(Oc2cccc(Cl)n2)CC1,,C1CCOC1,O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06432993B1,CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(-n3ccnc3)cc2)ccc1[N+](=O)[O-]>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(-n3ccnc3)cc2)ccc1N,[Pd],CN(C)C=O,,,,test
US20050277655A1,COc1ccc(F)cc1C(=O)c1cnc(Cl)nc1Cl.NN>>COc1ccc(F)cc1-c1n[nH]c2nc(Cl)ncc12,,C1CCOC1,,,,test
US20110135671A1,CCCCNc1nc(N)c2nc(OC)n(CCCCl)c2n1.CN1CCNCC1>>CCCCNc1nc(N)c2nc(OC)n(CCCN3CCN(C)CC3)c2n1,,CC#N,,CCN(C(C)C)C(C)C,,test
US05248684,CCCCOC(=O)c1cc(=O)n(CCCC)c2ccccc12>>CCCCn1c(=O)cc(C(=O)O)c2ccccc21,,C1COCCO1,,O,[Na+].[OH-],test
US20120122863A1,CCCC[C@H](N)C(=O)OC.COc1ccc2[nH]c(=O)oc(=O)c2c1>>CCCC[C@H](NC(=O)c1cc(OC)ccc1N)C(=O)OC,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,Cl,test
US20150274628A1,CCCCCCCCCCCCCC1=C(O)C(=O)C=C(NCCCC(=O)OCc2ccccc2)C1=O.COS(=O)(=O)OC>>CCCCCCCCCCCCCC1=C(OC)C(=O)C=C(NCCCC(=O)OCc2ccccc2)C1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140206706A1,O=C(CNC(=O)[C@H](Cc1ccccc1)N1C(=O)c2ccccc2C1=O)c1ccccc1>>O=C1c2ccccc2C(=O)N1[C@@H](Cc1ccccc1)c1ncc(-c2ccccc2)o1,,CN(C)C=O,,O=P(Cl)(Cl)Cl,,test
US20120165310A1,Cc1ccc(S(=O)(=O)OCC2(O)CC(n3cc(-c4cccc(OCC56CCC(CC5)O6)c4)c4c(N)ncnc43)C2)cc1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCC1(O)CC(n2cc(-c3cccc(OCC45CCC(CC4)O5)c3)c3c(N)ncnc32)C1,,CN(C)C=O,,O,,test
US20100152491A1,COc1ccc(C=O)cc1OS(=O)(=O)c1ccc(C)cc1>>COc1ccc(CO)cc1OS(=O)(=O)c1ccc(C)cc1,,CO,,O,[BH4-].[Na+],test
US06235707B1,CCOC(=O)NC(CC1CCC1)C(=O)OC>>CCOC(=O)N[C@@H](CC1CCC1)C(=O)O,,c1ccccc1,,O,[Na+].[OH-],test
US20120208741A1,CC/C(C=O)=C\c1ccc(C)cc1>>CC/C(=C\c1ccc(C)cc1)CO,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130237573A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@]1(C(=O)O)[C@H](OCc2ccc(Cl)c(Cl)c2)[C@@H](O)[C@@H]2[C@H]1[C@H]2C(=O)O>>CC(C)(C)OC(=O)N[C@@]1(C(=O)O)[C@H](OCc2ccc(Cl)c(Cl)c2)[C@@H](O)[C@@H]2[C@H]1[C@H]2C(=O)O,,C1COCCO1,,O=C([O-])O.[Na+],,test
US04296128,O=C(OCc1ccccc1)C(CCSc1ccccc1)C(=O)OCc1ccccc1>>O=C(O)C(CCSc1ccccc1)C(=O)OCc1ccccc1,,C1COCCO1,,[Na+].[OH-],,test
US20050165042A1,N#Cc1cc2c(cc1O)CCC=C2.O=C(CCl)c1ccc(Cl)cc1Cl>>Nc1c(C(=O)c2ccc(Cl)cc2Cl)oc2cc3c(cc12)C=CCC3,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090170898A1,CC(C)(C)OC(=O)N[C@H]1CCN(c2cccc3ncccc23)C1>>N[C@H]1CCN(c2cccc3ncccc23)C1,,O=C(O)C(F)(F)F,,,,test
US05294734,CC(=O)Cl.CCOC(CCCN)OCC>>CCOC(CCCNC(C)=O)OCC,,ClCCl,,O=C([O-])O.[Na+],,test
US20020128270A1,C[C@@H]([C@H](COCc1ccccc1)NC(=O)OC(C)(C)C)N(CCOS(C)(=O)=O)S(C)(=O)=O>>C[C@H]1[C@H](COCc2ccccc2)N(C(=O)OC(C)(C)C)CCN1S(C)(=O)=O,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20100048561A1,CN1CCC(N)CC1.COc1cc(C(=O)O)ccc1Nc1ncc2c(Br)ccc(OC3CCNCC3)c2n1>>COc1cc(C(=O)NC2CCCCN2C)ccc1Nc1ncc2c(Br)ccc(OC3CCNCC3)c2n1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130158025A1,CCOC(=O)CC(=O)c1ccc(F)cc1.Nc1[nH]nc(C2CC2)c1-c1ccc(Cl)cc1>>O=c1cc(-c2ccc(F)cc2)n2nc(C3CC3)c(-c3ccc(Cl)cc3)c2[nH]1,,c1ccncc1,,,,test
US20110059957A1,C#Cc1csc(C2CCN(C(=O)OC(C)(C)C)CC2)n1>>C#Cc1csc(C2CCNCC2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040082559A1,CC(C)(C)OC(=O)N(CCCOC1NCc2ccccc2CC1CC(=O)O)c1ccccn1.CC(C)(C)OC(=O)N(CCCOc1ccc2c(c1)CN(Cc1ccc(C(F)(F)F)cc1)C(=O)C(CC(=O)O)C2)c1ccccn1>>Nc1ccc(CN2Cc3cc(OCCCNc4ccccn4)ccc3CC(CC(=O)O)C2=O)cc1,,O,,O=C(O)C(F)(F)F,,test
US20040167198A1,Nc1ccccc1-c1cc2ccccc2[nH]1.O=C(O)Cc1ccc(O)cc1>>O=C(Cc1ccc(O)cc1)Nc1ccccc1-c1cc2ccccc2[nH]1,,CC#N,,CCN=C=NCCCN(C)C,Cl,test
US20100075948A1,CC(C)(C)CC1NC(C(=O)OC(C)(C)C)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(F)cc1.O=C(O)C(F)(F)F>>CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(F)cc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20080269214A1,CN.COC(=O)c1cc(-c2ccc(NC(=O)OC(C)(C)C)cn2)cnc1Cl>>CNc1ncc(-c2ccc(N)cn2)cc1C(=O)OC,,C1CCOC1,,,,test
US20090227602A1,CC(C)C(N)=O.Cc1ccc(S(=O)O)cc1.O=Cc1ccc(F)cc1>>Cc1ccc(S(=O)(=O)C(NC(=O)C(C)C)c2ccc(F)cc2)cc1,,CC#N,Cc1ccccc1,C[Si](C)(C)Cl,,test
US20140037538A1,C#CCNC.O=C(Cl)c1ccc(C(F)(F)F)nc1>>C#CCN(C)C(=O)c1ccc(C(F)(F)F)nc1,,ClCCl,,c1ccncc1,,test
US20090012084A1,COc1cc2nnc(C(N)=O)c(Nc3ccc(C)cc3F)c2cc1C1=CCN(C(=O)OC(C)(C)C)CC1>>COc1cc2nnc(C(N)=O)c(Nc3ccc(C)cc3F)c2cc1C1=CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040077605A1,CC(=O)Nc1cccc2c(Cl)cccc12.O=[N+]([O-])O>>Nc1ccc([N+](=O)[O-])c2c(Cl)cccc12,,CC(=O)O,CCO,[Na+].[OH-],,test
US04255351,C=C(C)C.O=C(Cl)C(Cl)CC(Cl)(Cl)Cl>>CC1(C)CC(=O)C1(Cl)CC(Cl)(Cl)Cl,,C1CCCCC1,,CCN(CC)CC,,test
US20100137587A1,CCOC(=O)c1ccc(-c2ccccc2)[nH]1.COCCCCOS(C)(=O)=O>>CCOC(=O)c1ccc(-c2ccccc2)n1CCCCOC,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US08877747B2,CC(=O)Oc1ccc2c(c1)C(=O)CC2c1ccccc1.O=C1CCC(=O)N1Br>>CC(=O)Oc1ccc2c(c1)C(=O)C(Br)=C2c1ccccc1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20130029963A1,CC=O.Cc1cccc(N)n1>>CCNc1cccc(C)n1,CC(=O)O,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090131379A1,C=C1[C@H](O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C/C(=C\C(=O)OC)C[C@@H]1F>>C=C1[C@H](O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C/C(=C\CO)C[C@@H]1F,,Cc1ccccc1,ClCCl,CC(C)C[Al+]CC(C)C.[H-],,test
US04730008,CCNCC.O=C(Cl)Cc1ccc(I)cc1>>CCN(CC)C(=O)Cc1ccc(I)cc1,,CCN(CC)CC,,,,test
US20150252038A1,C[C@@H](c1cc(Cl)cc(Cl)c1)N1CCC[C@@H](Oc2cc(F)c(C(=O)[O-])cc2C2CC2)C1>>C[C@@H](c1cc(Cl)cc(Cl)c1)N1CCC[C@@H](Oc2cc(F)c(C(=O)O)cc2C2CC2)C1,,O,,Cl,[Li+].[OH-],test
US20140005132A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43C)[C@@H]1CCC2=O>>CC(C)(C)[Si](O[C@H]1CC[C@@]2(C)C(=CCC3C4CCC(=O)[C@@]4(C)CCC32)C1)(c1ccccc1)c1ccccc1,,ClCCl,,c1c[nH]cn1,,test
US07094798B1,COc1ccc2c(c1)c1c3c(c(-c4ccccc4Cl)cc1n2CCC#N)C(=O)NC3=O>>N#CCCn1c2ccc(O)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O,,CO,,,,test
US20150315188A1,Clc1ccc2[nH]c3c(c2c1)[C@H]1CCCN1CC3.c1cc(C2CO2)ccn1>>OC(Cn1c2c(c3cc(Cl)ccc31)[C@H]1CCCN1CC2)c1ccncc1,,CN(C)C=O,,[H-].[Na+],,test
US20040192728A1,CCOC(=O)C(=CNc1ccc(F)cc1)C(=O)OCC>>CCOC(=O)c1c[nH]c2ccc(F)cc2c1=O,,c1ccc(Oc2ccccc2)cc1,,,,test
US20130237519A1,COC(=O)c1ccc(-c2ccn3c(C(=O)Nc4cc(C(=O)NCCN5CCCC5(C)C)ccc4F)cnc3c2)cc1F>>CC1(C)CCCN1CCNC(=O)c1ccc(F)c(NC(=O)c2cnc3cc(-c4ccc(C(=O)O)c(F)c4)ccn23)c1,,CO,,[Na+].[OH-],,test
US20130045964A1,CCOC(=O)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1>>O=C(O)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1,,C1CCOC1,,CO,[Li+].[OH-],test
US20090253758A1,CC(C)(C)[Si](C)(C)Cl.C[C@H](O)[C@@H](Nc1ccc(C#N)c(Cl)c1)C(=O)NNC(=O)c1ccc(S(C)(=O)=O)cc1>>C[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](Nc1ccc(C#N)c(Cl)c1)C(=O)NNC(=O)c1ccc(S(C)(=O)=O)cc1,,CN(C)C=O,,O,c1c[nH]cn1,test
US20090286812A1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.Oc1cccnc1>>CC(C)(C)OC(=O)N1CCC(n2ncc3c(Oc4cccnc4)ncnc32)CC1,,CN(C)C=O,O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20060229335A1,BrBr.Cn1nccc1-c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>Cn1ncc(Br)c1-c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1,,CCOC(C)=O,ClCCl,,,test
US04696763,O=C(O)CC(C(O)=S)c1nc2ccccc2s1>>O=C1CC(c2nc3ccccc3s2)C(=S)O1,,COCCOC,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20090192156A1,COC1CCNCC1.O=C(O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F>>COC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccccc34)ccc2F)CC1,,CC(=O)N(C)C,O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150126522A1,CC(C)I.COC(=O)c1cc(Cl)cc(O)c1C>>COC(=O)c1cc(Cl)cc(OC(C)C)c1C,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US04363808,N#CCCCCl.c1ccc2[nH]cnc2c1>>N#CCCCn1cnc2ccccc21,,C1COCCO1,,[H-].[Na+],,test
US20090054411A1,CCOC(=O)c1cnc2cc(OCCOC)c(Cl)cc2c1O.O=S(Cl)Cl>>CCOC(=O)c1cnc2cc(OCCOC)c(Cl)cc2c1Cl,CN(C)C=O,CC#N,,O=C([O-])O.[Na+],,test
US20120122838A1,CC(C)N1CCC(O)CC1.C[C@H](Nc1ncnc2[nH]cnc12)c1cc2cccc(Cl)c2c(Cl)n1>>CC(C)N1CCC(Oc2nc([C@H](C)Nc3ncnc4[nH]cnc34)cc3cccc(Cl)c23)CC1,,C1CCOC1,,O,[H-].[Na+],test
US06274588B1,CC(C)(C(=O)Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.CNc1cnc(SC)nc1-c1ccccc1C>>CSc1ncc(N(C)C(=O)C(C)(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c(-c2ccccc2C)n1,,ClCCl,,CCN(C(C)C)C(C)C,[Na+].[OH-],test
US20030149034A1,CC(=S)Nc1n[nH]c2ccc(N3CCCS3(=O)=O)cc12.NO>>CC(=NO)Nc1n[nH]c2ccc(N3CCCS3(=O)=O)cc12,,CO,,Cl,O=C([O-])O.[Na+],test
US20140256805A1,C[C@@]12C[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3C[C@H]1CC[C@H]2O>>C[C@@]12C[C@@H]3CC[C@@H]4CC(=O)CC[C@@H]4[C@H]3C[C@H]1CC[C@H]2O,[Pd],c1ccncc1,,,,test
US20090291917A1,IC1CCCC1.N#Cc1ccc(Oc2ccc3c(c2)COB3O)cc1O>>N#Cc1ccc(Oc2ccc3c(c2)COB3O)cc1OC1CCCC1,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US05273999,CC(=O)Cl.COC(=O)CCc1ccccc1OCCCCCOC(C)=O>>COC(=O)CCc1cc(C(C)=O)ccc1OCCCCCOC(C)=O,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20110312945A1,CCOC(=O)CBr.Cc1[nH]c2c(c1Cc1ccccc1S(=O)(=O)N1CCCC1)C(=O)C(C)(C)C(C)(C)C2>>CCOC(=O)Cn1c(C)c(Cc2ccccc2S(=O)(=O)N2CCCC2)c2c1CC(C)(C)C(C)(C)C2=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140094473A1,CCOC(=O)C1CCC1.CI>>CCOC(=O)C1(C)CCC1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20140163025A1,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5cc(OC6CCOCC6)ccc5F)ccc(F)c43)ccc21>>O=C(O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5cc(OC6CCOCC6)ccc5F)ccc(F)c43)ccc21,,CCO,,[K+].[OH-],,test
US20110275610A1,N#Cc1ccc(C2OCCO2)cc1.NO>>N/C(=N\O)c1ccc(C2OCCO2)cc1,,CO,,Cl,O=C([O-])O.[Na+],test
US06153793,CN(C)CC(=O)O.CNO>>CN(C)CC(=O)N(C)O,,ClC(Cl)Cl,,,,test
US20110166169A1,CN(C)CCN.N#Cc1ccc(-n2c3ccccc3c3c(-c4nc5ccc(F)cc5[nH]4)cccc32)cc1F.OO>>CN(C)CCNc1cc(-n2c3ccccc3c3c(-c4nc5ccc(F)cc5[nH]4)cccc32)ccc1C(N)=O,,CCO,CS(C)=O,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US04017497,COc1ccc2c(c1)[C@@]13CCCC4O[C@@]41[C@@H](C2)NCC3>>COc1ccc2c(c1)[C@@]13CCCC[C@@]1(O)[C@@H](C2)NCC3,,CCOCC,,C1CCOC1,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20100197692A1,CCOC(=O)CBr.Fc1ccc(Br)c(OC2CCN(c3ncc4nc(S)[nH]c4n3)CC2)c1>>CCOC(=O)CSc1nc2cnc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2[nH]1,,C1CCOC1,,CCN(CC)CC,,test
US20100273739A1,CC(C)(C)OC(=O)NC1CCc2ccc(OC(F)F)cc2C1Cc1ccc(Cl)cc1.Cl>>Cl.NC1CCc2ccc(OC(F)F)cc2C1Cc1ccc(Cl)cc1,,ClCCl,,,,test
US20120010244A1,COCCS(=O)(=O)Cl.NC(=O)c1cc(Br)cc2c(C3CCNCC3)c[nH]c12>>COCCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(Br)cc23)CC1,,CCN(CC)CC,CN(C)C=O,Cl,O,test
US20130190293A1,Cc1ccc2c(c1)c1c(n2-c2cccc(Br)c2)CCN(C)C1.OB(O)c1cn[nH]c1>>Cc1ccc2c(c1)c1c(n2-c2cccc(-c3cn[nH]c3)c2)CCN(C)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])[O-].[K+].[K+],test
US20050197350A1,CI.Oc1cc(Cl)nc2ccccc12>>COc1cc(Cl)nc2ccccc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130045942A1,COc1ccc(C=O)cc1O.NO>>COc1ccc(C=NO)cc1O,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20030105118A1,CC(C)(C)[Si](C)(C)Cl.OCC1CCc2ccccc2N1>>CC(C)(C)[Si](C)(C)OCC1CCc2ccccc2N1,,CN(C)C=O,,c1c[nH]cn1,,test
US20150087646A1,CCn1c(-c2c(Cl)cccc2Cl)nn(-c2ccc(C(=O)OC)c(OC)c2)c1=O.Nc1cccc(C(F)(F)F)c1>>CCn1c(-c2c(Cl)cccc2Cl)nn(-c2ccc(C(=O)Nc3cccc(C(F)(F)F)c3)c(OC)c2)c1=O,,Cc1ccccc1,,C[Al](C)C,,test
US05874448,C=CC(=O)OC(C)(C)C.CCOC(=O)C(F)N1C(=O)c2ccccc2C1=O>>CCOC(=O)C(F)(CCC(=O)OC(C)(C)C)N1C(=O)c2ccccc2C1=O,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US04310547,C=O.CCCCCCCCCCCCNCCC(C)C>>CCCCCCCCCCCCN(C)CCC(C)C,,O=CO,,,,test
US20120282218A1,O=C(O)C(O)=CC(=O)c1cc(Cc2ccc(F)cc2F)cn(Cc2ccccc2F)c1=O.Oc1cccc2[nH]nnc12>>O=C(N[C@H]1CCC[C@@H]1O)C(O)=CC(=O)c1cc(Cc2ccc(F)cc2F)cn(Cc2ccccc2F)c1=O,,CN(C)C=O,ClC(Cl)Cl,O,O=C([O-])O.[Na+],test
US20010021718A1,BrCC1CCC1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>[Br-].c1ccc([P+](CC2CCC2)(c2ccccc2)c2ccccc2)cc1,,Cc1ccccc1,,CCCCCC,,test
US20100197651A1,CN(C)C=CC(=O)c1nn(-c2ccc(N3CCOCC3)cc2)ccc1=O.NNC1CCCC1>>O=c1ccn(-c2ccc(N3CCOCC3)cc2)nc1-c1ccnn1C1CCCC1,,CO,,,,test
US20090286833A1,CN(C)C(c1cccc(F)c1)C1CCC(C=O)CC1.NO>>CN(C)C(c1cccc(F)c1)C1CCC(C=NO)CC1,,CCO,,Cl,,test
US20130059834A1,CC(C)(C)OC(=O)NC1COCC(O)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NC1COCC(OS(C)(=O)=O)C1,CN(C)c1ccncc1,ClCCl,,,,test
US20100041891A1,CCOC(=O)c1cccc(-c2cccc3c(C)c(Cc4ccc(F)c(Cl)c4)sc23)c1>>Cc1c(Cc2ccc(F)c(Cl)c2)sc2c(-c3cccc(C(=O)O)c3)cccc12,,C1CCOC1,,CCO,[Na+].[OH-],test
US20100256092A1,COc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)cn1>>O=S(=O)(Nc1ccc2c(c1)B(O)OC2)c1ccc(O)nc1,,Cl,,O=C([O-])O.[Na+],,test
US04725688,CCC(C)C(=O)O.CCCCCCCCCCCOc1cnc(-c2ccc(O)cc2)nc1>>CCCCCCCCCCCOc1cnc(-c2ccc(OC(=O)[C@@H](C)CC)cc2)nc1,CN(C)c1ccncc1,ClC(Cl)Cl,,,,test
US20040152690A1,COC(=O)c1cnc(N2CCN(c3nc4c(-c5cc(F)c(F)c(F)c5)cc(C(F)(F)F)cc4[nH]3)[C@H](C)C2)c(Cl)c1>>C[C@@H]1CN(c2ncc(C(=O)O)cc2Cl)CCN1c1nc2cc(C(F)(F)F)cc(-c3cc(F)c(F)c(F)c3)c2[nH]1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20150329523A1,CS(=O)(=O)Oc1cccc([N+](=O)[O-])c1>>CS(=O)(=O)Oc1cccc(N)c1,[Pd],CCO,,[H][H],,test
US20030087930A1,CCOC(=O)C(NC(=O)c1ccc(Cl)cc1)C(=O)OCC.O=c1cc(CBr)c2ccccc2[nH]1>>CCOC(=O)C(Cc1cc(=O)[nH]c2ccccc12)(NC(=O)c1ccc(Cl)cc1)C(=O)OCC,,CCO,,C,C[O-].[Na+],test
US20110076292A1,CC(C)(C)NC(=O)CCl.CC(C)n1ncnc1-c1cn2c(n1)-c1ccc(C3CCNCC3)cc1OCC2>>CC(C)n1ncnc1-c1cn2c(n1)-c1ccc(C3CCN(CC(=O)NC(C)(C)C)CC3)cc1OCC2,,C1CCOC1,ClCCl,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20140005164A1,C#Cc1ccc2c(c1)n(C[C@@H]1CC[C@@H](C(=O)O)CC1)c(=O)n2C.CC(=O)N1CCNCC1>>C#Cc1ccc2c(c1)n(C[C@@H]1CC[C@@H](C(=O)N3CCN(C(C)=O)CC3)CC1)c(=O)n2C,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20090312327A1,C=C(F)CCl.COc1ccc(C(=O)N(C)C2CN(C(=O)C3CCNCC3)CC2c2ccc(Cl)c(Cl)c2)cc1C(F)(F)F>>C=C(F)CN1CCC(C(=O)N2CC(c3ccc(Cl)c(Cl)c3)C(N(C)C(=O)c3ccc(OC)c(C(F)(F)F)c3)C2)CC1,,C1CCOC1,CCOC(C)=O,,,test
US20020156081A1,CCOC(=O)[C@H]1CC[C@@H](n2nc(-c3ccc(Nc4nc5cc(C)cc(C)c5o4)cc3)c3c(N)ncnc32)CC1>>Cc1cc(C)c2oc(Nc3ccc(-c4nn([C@@H]5CC[C@H](C(=O)O)CC5)c5ncnc(N)c45)cc3)nc2c1,,CO,,Cl,[Na+].[OH-],test
US20110059951A1,CC(C)(C)OC(=O)N1CCCN(CC(CC#N)OS(C)(=O)=O)CC1.C[Si](C)(C)CCOCn1ccc2c(-c3cn[nH]c3)ncnc21>>CC(C)(C)OC(=O)N1CCCN(CC(CC#N)n2cc(-c3ncnc4c3ccn4COCC[Si](C)(C)C)cn2)CC1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US05833885,CC(=O)C(C)C.CN(N)c1ccc(C(F)(F)F)cn1>>CC(=NN(C)c1ccc(C(F)(F)F)cn1)C(C)C,,Cc1ccccc1C,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04971967,O=C(CCl)CSC(=S)Nc1ccc(F)c(F)c1F>>Fc1ccc(-n2c(CCl)csc2=S)c(F)c1F,,CO,,Cl,,test
US05629325,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cnc(Cl)c(Br)c1.OB(O)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cnc(Cl)c(-c2ccc(Cl)cc2)c1,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20160257676A1,NN.O=Cc1c(Cl)ncc2cc(Br)ccc12>>Brc1ccc2c(cnc3[nH]ncc32)c1,,COCCOC,,,,test
US20140243286A1,COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCN)c1nnc(C)n1-2.C[Si](C)(O)c1cccc(C(=O)O)c1>>COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCNC(=O)c1cccc([Si](C)(C)O)c1)c1nnc(C)n1-2,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20090137580A1,CC(C)(C)OC(=O)N1CCCC(N)C1.Cn1ccc2ncnc(Oc3ccc(N)c(Cl)c3)c21.O=C(Cl)Oc1ccccc1>>Cn1ccc2ncnc(Oc3ccc(NC(=O)NC4CCCN(C(=O)OC(C)(C)C)C4)c(Cl)c3)c21,,CN1CCCC1=O,,c1ccncc1,,test
US08293729B2,CS(=O)(=O)c1ccc(N2CCC(=NOC3CCNCC3)CC2)c(F)c1.O=C(Oc1ccc([N+](=O)[O-])cc1)OC1CCC1>>CS(=O)(=O)c1ccc(N2CCC(=NOC3CCN(C(=O)OC4CCC4)CC3)CC2)c(F)c1,,ClCCl,,,,test
US20140011800A1,CCOC(=O)c1cc2c(N[C@@H]3CCN(C(=O)OC(C)(C)C)CC3(C)C)c(C(N)=O)cnn2c1>>CC(C)(C)OC(=O)N1CC[C@@H](Nc2c(C(N)=O)cnn3cc(C(=O)O)cc23)C(C)(C)C1,,C1CCOC1,CO,[Na+].[OH-],,test
US05130119,Nc1ccc(F)cc1C(F)(F)F.O=C(O)c1ccc(S(=O)(=O)Cl)cc1>>O=C(O)c1ccc(S(=O)(=O)Nc2ccc(F)cc2C(F)(F)F)cc1,,ClCCl,,c1ccncc1,,test
US20090324581A1,COC(=O)c1ccc(CC(C)C)c(C(F)(F)F)c1>>CC(C)Cc1ccc(CO)cc1C(F)(F)F,,C1CCOC1,,Cl,[BH4-].[Li+],test
US20140080822A1,CI.COC(=O)c1c(N)ccc2c1OCC(=S)N2>>COC(=O)c1c(N)ccc2c1OCC(SC)=N2,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090029905A1,CC(C)(C)OC(=O)n1ccc(N)n1.COC[C@H](C)Oc1cc(OCc2ccccc2)cc(C(=O)O)c1>>COC[C@H](C)Oc1cc(OCc2ccccc2)cc(C(=O)Nc2ccn(C(=O)OC(C)(C)C)n2)c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090029994A1,CCNC(=O)N(CC)c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(OCCCC(=O)OCC)cn1>>CCNC(=O)N(CC)c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(OCCCC(=O)O)cn1,,CCO,,CCOC(C)=O,[Na+].[OH-],test
US05262565,CI.COCOc1c(O)ccc2cccc(Cc3ccccc3)c12>>COc1ccc2cccc(Cc3ccccc3)c2c1O,,CN(C)C=O,,[H-].[Na+],,test
US20080318935A1,CCOC(=O)c1nc(-c2ccccc2)n2c1CN(C(=O)OC(C)(C)C)CCC2>>CC(C)(C)OC(=O)N1CCCn2c(-c3ccccc3)nc(C(=O)O)c2C1,,CO,,O,[Li+].[OH-],test
US20090197891A1,COc1ccc(C(=O)O)c(OC)c1OC.O=C(Cl)C(=O)Cl>>COc1ccc(C(=O)Cl)c(OC)c1OC,CN(C)C=O,Cc1ccccc1,,,,test
US20120142706A1,COc1ccc(Cn2nc(C)c3cc([N+](=O)[O-])ccc32)cc1>>COc1ccc(Cn2nc(C)c3cc(N)ccc32)cc1,[Pd],CO,,CCOC(C)=O,,test
US20060270612A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.Cc1ccc(=O)n(-c2ccccc2)c1>>Cc1ccc(=S)n(-c2ccccc2)c1,,Cc1ccccc1,,,,test
US20100009969A1,CC1CCCN1CCCOc1ccc(-c2nc3c(s2)CCC3NC(=O)OCc2ccccc2)cc1>>CC1CCCN1CCCOc1ccc(-c2nc3c(s2)CCC3N)cc1,,Cl,,,,test
US03931302,COC(=O)C(C)=CCc1cccc(C(=O)c2ccccc2)c1>>CC(=CCc1cccc(C(=O)c2ccccc2)c1)C(=O)O,,O,,CCO,[K+].[OH-],test
US20140323475A1,CC(C)(C)O[Na].CCc1cc(Cl)ccc1COc1ccc(Cl)cc1Cn1ccc2c(C(=O)O)cccc21>>CCc1cc(Cl)ccc1COc1ccc(Cl)cc1Cn1ccc2c(C(=O)[O-])cccc21.[Na+],,CO,,,,test
US20050245741A1,CNC(=O)c1ccccc1O.O=[N+]([O-])c1cccc(S(=O)(=O)OC[C@@H]2CO2)c1>>CNC(=O)c1ccccc1OC[C@@H]1CO1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05736568,CN(CCCl)Cc1ccccc1.COc1ccc(O)c(C=O)c1>>COc1ccc(OCCN(C)Cc2ccccc2)c(C=O)c1,,CN(C)C=O,Cc1ccccc1,[H-].[Na+],,test
US20140088117A1,Cn1ncc([N+](=O)[O-])c1C1CCC(O)COC1>>Cn1ncc([N+](=O)[O-])c1C1CCC(=O)COC1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US20160039783A1,O=C1CCC(=O)N1I.O=Cc1csc(Cl)c1Br>>O=Cc1c(I)sc(Cl)c1Br,,O=C(O)C(F)(F)F,,CCOC(C)=O,,test
US04045433,CN=C=O.O=C1CNC(c2ccccc2)c2cc([N+](=O)[O-])ccc2N1>>CNC(=O)N1CC(=O)Nc2ccc([N+](=O)[O-])cc2C1c1ccccc1,,CCOCC,,,,test
US05166214,CCCCCCC(=O)Cl.NCCCCCNc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1>>CCCCCCC(=O)NCCCCCNc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1,,ClCCl,,CCN(CC)CC,O,test
US05591762,CCCCc1nc2c(C)cc(NC(=O)N3CCOCC3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc2c(C)cc(NC(=O)N3CCOCC3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110034440A1,CCN(CCNC(=O)CN(CC(=O)N(C)N1Cc2ccccc2C1)c1cc(C(N)=NO)ccc1C)C(=O)OC(C)(C)C.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCN(CCNC(=O)CN(CC(=O)N(C)N1Cc2ccccc2C1)c1cc(-c2noc(C(F)(F)F)n2)ccc1C)C(=O)OC(C)(C)C,,CCCCCC,CCOC(C)=O,CCN(CC)CC,CN(C)C=O,test
US06894062B1,C=C(C=O)CC.Nc1ccccc1Br.O=[N+]([O-])c1cccc(S(=O)(=O)[O-])c1>>CCc1cnc2c(C3CCCNC3)cccc2c1,,O,,O=S(=O)(O)O,,test
US20120115893A1,CO/N=C1/CCc2cc(C(C)(C)C)ccc21>>CC(C)(C)c1ccc2c(c1)CCC2N,[Pd],CO,,N,,test
US06388092B2,COc1cccc(-c2cc(OC)nc3ccc(C(O)(c4ccc(Cl)s4)c4cncn4C)cc23)c1>>COc1cccc(C2CC(=O)Nc3ccc(C(O)(c4ccc(Cl)s4)c4cncn4C)cc32)c1,,C1CCOC1,,Cl,,test
US04283341,CC(C)=CCOC(=O)C=[N+]=[N-]>>CC1(C)C2COC(=O)C21,[Cu],C1COCCO1,,,,test
US20110105461A1,CS(=O)(=O)c1ccc2c(c1)O[C@@H](CN)CO2.FC(F)(F)CCI>>CS(=O)(=O)c1ccc2c(c1)O[C@@H](CNCCC(F)(F)F)CO2,,CC#N,,,,test
US04772600,Nc1ccccc1Cl.O=C(O)Cn1c(-c2ccc(Br)cc2)nc2cccnc21>>O=C(Cn1c(-c2ccc(Br)cc2)nc2cccnc21)Nc1ccccc1Cl,,CN(C)C=O,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20100160327A1,Nc1ccccc1N.O=C(O)c1ccc(C(O)(C(=O)Nc2ccccc2)C(=O)Nc2ccccc2)cc1>>Nc1ccccc1NC(=O)c1ccc(C(O)(C(=O)Nc2ccccc2)C(=O)Nc2ccccc2)cc1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20150157997A1,O=[N+]([O-])C(c1ccccc1)([N+](=O)[O-])[N+](=O)[O-].O=[N+]([O-])N1CN([N+](=O)[O-])CN([N+](=O)[O-])C1>>O=[N+]([O-])C(c1ccccc1)([N+](=O)[O-])[N+](=O)[O-].O=[N+]([O-])N1CN([N+](=O)[O-])CN([N+](=O)[O-])C1,,CC(C)=O,,,,test
US05750550,COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(CBr)C2=O.Oc1cc(C(F)(F)F)nn1-c1ccc2ccccc2n1>>COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(COc1cc(C(F)(F)F)nn1-c1ccc3ccccc3n1)C2=O,,CN(C)C=O,,[F-].[K+],,test
US20120065233A1,COc1nccc(Cl)c1-c1nc2c(C)c3c(cc2[nH]1)C(=O)N(CCN(C)C)C3=O>>Cc1c2c(cc3[nH]c(-c4c(Cl)cc[nH]c4=O)nc13)C(=O)N(CCN(C)C)C2=O,,C1COCCO1,,Cl,,test
US03973033,O=S(Cl)Cl.OCc1cccc2c1CCCC2>>ClCc1cccc2c1CCCC2,,ClC(Cl)Cl,,c1ccncc1,,test
US06218431B1,CCOC(=O)c1c(C(C)C)nc(C(C)C)c(C=O)c1-c1ccc(F)cc1.[Li]CCCC>>CCCCC(O)c1c(C(C)C)nc(C(C)C)c(CO)c1-c1ccc(F)cc1,,CCCCCC,CCOC(C)=O,,,test
US20130302416A1,CCc1cccc(CC)c1NC(=O)c1nn(C)c2c1CCCc1cnc(Nc3ccc(C(=O)O)cc3OC)nc1-2.CN1CCC(N)CC1>>CCc1cccc(CC)c1NC(=O)c1nn(C)c2c1CCCc1cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc1-2,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20040142922A1,CCOC(=O)c1ccc(O)c(O)c1.Fc1cc(F)cc(C(Cl)(Cl)c2cc(F)cc(F)c2)c1>>CCOC(=O)c1ccc2c(c1)OC(c1cc(F)cc(F)c1)(c1cc(F)cc(F)c1)O2,,ClCCl,,,,test
US20040077877A1,C#Cc1ccccc1.Fc1ccc(-c2nn(C3CCCCO3)c3ccc(Br)cc23)cc1>>Fc1ccc(-c2n[nH]c3ccc(C#Cc4ccccc4)cc23)cc1,,CC#N,,CCN(CC)CC,Cc1ccccc1P(c1ccccc1C)c1ccccc1C,test
US20130178505A1,CO.O=C(O)c1cc(=O)c2ccccc2[nH]1>>COC(=O)c1cc(O)c2ccccc2n1,O=S(=O)(O)O,,,,,test
US20110152519A1,O=N[O-].c1ccc(N2CCN(c3nc(N4CCOCC4)cc(N4CCOCC4)n3)CC2)cc1>>Nc1c(N2CCOCC2)nc(N2CCN(c3ccccc3)CC2)nc1N1CCOCC1,,CC(=O)O,,O,,test
US20140243310A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.Oc1cnc(Cl)c(F)c1>>CC(C)(C)[Si](Oc1cnc(Cl)c(F)c1)(c1ccccc1)c1ccccc1,,O,,CN(C)C=O,c1c[nH]cn1,test
US04617301,CCOC(=O)C(CCc1ccccc1)NC1CCCC2SCC(C(=O)O)N2C1=O.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)C(CCc1ccccc1)NC1CCCC2N(C1=O)C(C(=O)O)CS2=O,,CCO,,Cl,,test
US20020010182A1,CC(=O)Cl.Nc1ccc(CN2CCN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](Cc3ccc(Cl)c(Cl)c3)C2)cc1>>CC(=O)Nc1ccc(CN2CCN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](Cc3ccc(Cl)c(Cl)c3)C2)cc1,,O,,,,test
US05571810,CN.CS(=O)(=O)c1ccc(-c2ccsc2-c2ccc(F)cc2)cc1.O=S(=O)(O)Cl>>CNS(=O)(=O)c1cc(-c2ccc(S(C)(=O)=O)cc2)c(-c2ccc(F)cc2)s1,,C1CCOC1,,,,test
US20100158818A1,CCCCN(CCCC)C(=O)CC(C)(C)N=[N+]=[N-]>>CCCCN(CCCC)CCC(C)(C)N,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150299189A1,COC(=O)c1cc(C2CC2)cnc1Nc1ccc2c(ccn2C(=O)OC(C)(C)C)c1>>COC(=O)c1cc(C2CC2)cnc1Nc1ccc2[nH]ccc2c1,,CC(=O)N(C)C,,,,test
US20060063785A1,CCCCN=C=O.Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1>>CCCCNC(=O)Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1,,C1CCOC1,,CCN(CC)CC,,test
US20120101099A1,C#Cc1ccc(C=O)cc1>>C#Cc1ccc(CO)cc1,,CO,,[BH4-].[Na+],,test
US20070179167A1,Cc1cc(C=O)cc(C)c1OC(C)C.NO>>Cc1cc(C=NO)cc(C)c1OC(C)C,,CCO,CCOC(C)=O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20070043023A1,c1ccc(CN2CCC3(CCCc4ccccc43)CC2)cc1>>c1ccc2c(c1)CCCC21CCNCC1,[Pd],CO,,O=C[O-].[NH4+],,test
US04041071,CCN.O=C(Cl)/C=C/c1cccc(Cl)c1>>CCNC(=O)/C=C/c1cccc(Cl)c1,,CCOCC,c1ccccc1,,,test
US20050009843A1,CC(=O)OCC(=O)N[C@H]1CCCN(c2nc3cc(C(=O)Nc4nc(C(C)(C)C)cs4)ccn3c(=O)c2/C=C/C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)/C=C/c1c(N2CCC[C@H](NC(=O)CO)C2)nc2cc(C(=O)Nc3nc(C(C)(C)C)cs3)ccn2c1=O,,C1CCOC1,,[Na+].[OH-],,test
US20130116234A1,C[Sn](C)(C)N=[N+]=[N-].N#Cc1c(N2CCCC2)nc2ccc(Cl)cc2c1-c1ccccc1>>Clc1ccc2nc(N3CCCC3)c(-c3nnn[nH]3)c(-c3ccccc3)c2c1,,Cc1ccccc1C,,,,test
US20160122336A1,C[Si](C)(C)C(F)(F)F.O=C(c1ccc(Br)c(F)c1Cl)C(F)(F)F>>OC(c1ccc(Br)c(F)c1Cl)(C(F)(F)F)C(F)(F)F,,O,,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20050215595A1,CC(C)(C)OC(=O)n1nc(-c2ccccc2Cl)c2ccc(Oc3ccccc3F)cc21>>Fc1ccccc1Oc1ccc2c(-c3ccccc3Cl)n[nH]c2c1,,CO,,C[O-].[Na+],,test
US20160016948A1,C1=COCCC1.CC(O)c1nc2cnc(Br)cc2n1C(C)C>>CC(OC1CCCCO1)c1nc2cnc(Br)cc2n1C(C)C,,C1CCOC1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05534518,Cc1c([N+](=O)[O-])ccc(Cl)c1C#N.N=C(N)N>>Cc1c([N+](=O)[O-])ccc2nc(N)nc(N)c12,,CCOCCO,,O=C(O)O,,test
US20100317657A1,CN(C)C(=O)CBr.Cc1n[nH]cc1[N+](=O)[O-]>>Cc1nn(CC(=O)N(C)C)cc1[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],,test
US04064259,C=CCCCCNC(=O)c1cnc(OCC(O)CNC(C)(C)C)s1.Cl>>C=CCCCCNC(=O)c1cnc(OCC(O)CNC(C)(C)C)s1.Cl,,CCOCC,,,,test
US20110118275A1,Nc1cnccc1O.Nc1nccnc1C(=O)O>>Nc1nccnc1C(=O)Nc1cnccc1O,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20120208828A1,Cc1ccc(-c2nnc(CCl)o2)cc1.Fc1ccc(-c2nnc(S)n2-c2ccccc2Cl)cc1>>Cc1ccc(-c2nnc(CSc3nnc(-c4ccc(F)cc4)n3-c3ccccc3Cl)o2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150133422A1,NC(=O)CCBr.O=S(=O)(c1ccccc1)n1cc(-c2cn[nH]c2)c2ccc(F)cc21>>NC(=O)CCn1cc(-c2cn(S(=O)(=O)c3ccccc3)c3cc(F)ccc23)cn1,,CC#N,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US06297196B1,Cc1cc(Br)c(C)c2c1SCCC21OCCO1.O=C=O>>Cc1cc(C(=O)O)c(C)c2c1SCCC2=O,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20100197715A1,CI.O=C(O)c1ccc(C(F)(F)F)cc1Br>>COC(=O)c1ccc(C(F)(F)F)cc1Br,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05308860,CC(C)(C)S(=O)(=O)CC#N.CS(=O)(=O)OCCc1ccc(Cl)cc1>>CC(C)(C)S(=O)(=O)C(C#N)CCc1ccc(Cl)cc1,,CN(C)C=O,,,,test
US20030092677A1,CC(C)(C)OC(=O)Nc1ccc(-c2cccc(F)c2F)cc1NC(=O)CC(=O)c1cccc(C#N)c1>>N#Cc1cccc(C2=Nc3ccc(-c4cccc(F)c4F)cc3NC(=O)C2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120004203A1,CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(N)nc2N1c1cccc(C(F)(F)F)c1.O=C(Cl)C1(F)CC1>>CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(NC(=O)C3(F)CC3)nc2N1c1cccc(C(F)(F)F)c1,,C1CCOC1,,Cl,c1ccncc1,test
US20020052397A1,CC1(C)OCC(=O)CO1.Cn1cc(C2=C(c3cccc(N)c3)C(=O)NC2=O)c2ccccc21>>Cn1cc(C2=C(c3cccc(NC4COC(C)(C)OC4)c3)C(=O)NC2=O)c2ccccc21,,CO,,[BH3-]C#N.[Na+],,test
US20040248854A1,CCOC(=O)COCCCCN1C(=O)CCC[C@@H]1C=O.COP(=O)(CC(=O)Cc1cccc(Cl)c1)OC>>CCOC(=O)COCCCCN1C(=O)CCC[C@@H]1/C=C/C(=O)Cc1cccc(Cl)c1,,C1CCOC1,,[H-].[Na+],,test
US20150141406A1,CC1(C)OB(c2ccc(S(N)(=O)=O)cc2)OC1(C)C.COc1nccc2c1c(I)cn2CC1COC(C)(C)O1>>COc1nccc2c1c(-c1ccc(S(N)(=O)=O)cc1)cn2CC1COC(C)(C)O1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04210659,BrCCBr.N=c1[nH]ccn1-c1c(Cl)cccc1Cl>>Clc1cccc(Cl)c1N1C=CN2CCN=C21,,Cl,,,,test
US20140336106A1,COc1ccc([C@@H](O)[C@H](NC(=O)[C@H](CO)NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2)cc1>>COc1ccc([C@@H](O)[C@H](NC(=O)[C@@H](N)CO)C(=O)OCc2ccccc2)cc1,,ClCCl,,CCOC(C)=O,Cl,test
US20110130415A1,CC1(CO)COC1.Cn1nnn(-c2cc([N+](=O)[O-])ccc2F)c1=O>>Cn1nnn(-c2cc([N+](=O)[O-])ccc2OCC2(C)COC2)c1=O,,CN(C)C=O,O,CCOC(C)=O,[H-].[Na+],test
US20090143366A1,NCC(=O)Nc1ccc(Br)cc1C(=O)c1ccccc1F>>O=C1CN=C(c2ccccc2F)c2cc(Br)ccc2N1,,CC(=O)O,,CCO,,test
US03931277,CCNS(C)(=O)=O.O=C=NS(=O)(=O)Cl>>CCN(S(C)(=O)=O)S(=O)(=O)N=C=O,,Clc1ccccc1,,,,test
US20100227880A1,CCOC(=O)c1c(CN(C)C2CCCc3cccnc32)nc2ccccn12>>CN(Cc1nc2ccccn2c1C(=O)O)C1CCCc2cccnc21,,CO,,[Na+].[OH-],,test
US20140031360A1,CCC(=O)Nc1ccc2c(c1)c(-c1cncc(N3CCC(NC(=O)OC(C)(C)C)CC3)n1)cn2C(=O)OC(C)(C)C>>CCC(=O)Nc1ccc2[nH]cc(-c3cncc(N4CCC(N)CC4)n3)c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04144263,CCOC(=O)C(C#N)(Cc1cc(OC)c(OC)c(OC)c1)C(OCC)OCC.N=C(N)N>>COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC,,CCO,,[K+].[OH-],,test
US04873255,CCOC(=O)C(Cl)Cc1ccc(OCC2(C)CCc3c(C)cc(C)cc3O2)cc1.NC(N)=S.O=S1(=O)CCCC1>>Cc1cc(C)c2c(c1)OC(C)(COc1ccc(CC3SC(=O)NC3=O)cc1)CC2,,COCCO,,Cl,,test
US07368458B2,CC(C)(C)OC(=O)Nc1ccc(-c2ccccc2)nc1.O=CN1CCCCC1>>CC(C)(C)OC(=O)Nc1cnc(-c2ccccc2)cc1C=O,,C1CCOC1,,CN(C)CCN(C)C,[Li]CCCC,test
US20060041164A1,CC(C)(C)OC(=O)NCCCO.COC(=O)Cc1cccc(O)c1>>COC(=O)Cc1cccc(OCCCNC(=O)OC(C)(C)C)c1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150252036A1,BrBr.CC(C)c1ccccc1O>>CC(C)c1cc(Br)ccc1O,,ClCCl,,O=C([O-])O.[Na+],,test
US20090264399A1,CN(C)S(=O)(=O)Cl.C[C@@H]1CCNC[C@@H]1n1c(=O)[nH]c2cnc3[nH]ccc3c21>>C[C@@H]1CCN(S(=O)(=O)N(C)C)C[C@@H]1n1c(=O)[nH]c2cnc3[nH]ccc3c21,,ClC(Cl)Cl,,C1COCCO1,O=C([O-])O.[Na+],test
US20080108580A1,CC(=O)c1ccc(F)cc1.COc1ccccc1O>>COc1ccccc1Oc1ccc(C(C)=O)cc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100099077A1,C=CCc1cc(C(=O)OC)cc(C)c1O.CC(C)(C)[Si](C)(C)Cl>>C=CCc1cc(C(=O)OC)cc(C)c1O[Si](C)(C)C(C)(C)C,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20060252797A1,CC1CC2(CCN1Cc1ccccc1)OCCO2>>CC1CC(=O)CCN1Cc1ccccc1,,c1ccccc1,,Cl,,test
US08680114B2,CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)O.c1cnc2ncnc(N3CCNCC3)c2c1>>CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)N1CCN(c2ncnc3ncccc23)CC1,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130175481A1,BrC(Br)(Br)Br.CCCCCCCCC(C=O)CCCCCC>>CCCCCCCCC(C=C(Br)Br)CCCCCC,,ClCCl,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090297685A1,CN(CC(=O)N1C[C@H](O)[C@@H](O)[C@@H](O)C1CO)C(=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C>>CN(CC(=O)N1C[C@H](O)[C@@H](O)[C@@H](O)C1CO)C(=N)N,,O,O=C(O)C(F)(F)F,,,test
US20090326229A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1cccc2[nH]c3ncc(Cl)cc3c12>>O=S(=O)(Oc1cccc2[nH]c3ncc(Cl)cc3c12)C(F)(F)F,,c1ccncc1,,[Cl-].[NH4+],,test
US20040176433A1,O=CNCc1[nH]nc(-c2ccc(F)cc2)c1-c1ccncc1>>CNCc1[nH]nc(-c2ccc(F)cc2)c1-c1ccncc1,,C1CCOC1,,B,Cl,test
US20110065734A1,CCOC(=O)C=Cc1cc[nH]c1.O=c1[nH]cnc2ccc(S(=O)(=O)Cl)cc12>>CCOC(=O)C=Cc1ccn(S(=O)(=O)c2ccc3nc[nH]c(=O)c3c2)c1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20100331293A1,O=[N+]([O-])c1cc(N2CCSCC2)cnc1N1CCOCC1>>Nc1cc(N2CCSCC2)cnc1N1CCOCC1,[Pd],CO,,,,test
US20040210080A1,CC(C)(C)C(=O)Cl.Nc1ccc(Br)cc1F>>CC(C)(C)C(=O)Nc1ccc(Br)cc1F,,c1ccncc1,,,,test
US05661183,Cc1c(C)c(C(=O)O)c(N)c(OCc2ccccc2)c1Cl>>Cc1c(C)c(C(=O)O)c(N)c(O)c1Cl,[Pd],CCO,,,,test
US20100303928A1,CCOC(=O)c1nc(C#C[Si](C)(C)C)c2c(-c3ccccc3)noc2c1O>>C#Cc1nc(C(=O)OCC)c(O)c2onc(-c3ccccc3)c12,,CCO,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130064770A1,Cn1c(=O)cnn(CCCCCl)c1=O.Fc1cccc(C2=CCNCC2)n1>>Cn1c(=O)cnn(CCCCN2CC=C(c3cccc(F)n3)CC2)c1=O,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US20100184815A1,CCCCCCN=C=O.NC(=O)NNC(=O)COC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCCCn1c(COC(c2ccccc2)(c2ccccc2)c2ccccc2)n[nH]c1=O,,C1CCOC1,,,,test
US20150232435A1,NCCCCN1CCN(c2cc(C(F)(F)F)nc3ccccc23)CC1.O=C(O)c1cn2ccccc2n1>>O=C(NCCCCN1CCN(c2cc(C(F)(F)F)nc3ccccc23)CC1)c1cn2ccccc2n1,,CO,ClC(Cl)Cl,,,test
US20010031760A1,CCOC(=O)C1CCNCC1.N#Cc1ccc2nc(Cl)nc(NCc3ccc4c(c3)OCO4)c2c1>>CCOC(=O)C1CCN(c2nc(NCc3ccc4c(c3)OCO4)c3cc(C#N)ccc3n2)CC1,,CC(C)O,,CCN(CC)CC,,test
US20110059948A1,COc1ccccc1N=C=O.COc1nc2ccc(Br)cc2c2c1C(C)(OCC(O)CN=[N+]=[N-])c1ccccc1-2.ClCCl>>COc1ccccc1N=C=NCC(COC1(C)c2ccccc2-c2c1c(OC)nc1ccc(Br)cc21)OC,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100324030A1,COc1cnc2cccc(O)c2c1.CS(=O)(=O)OCCN1CCN(C(=O)OCc2ccccc2)CC1>>COc1cnc2cccc(OCCN3CCN(C(=O)OCc4ccccc4)CC3)c2c1,,CN(C)C=O,,[H-].[Na+],,test
US20100273739A1,CC(C)(C)OC(=O)NC1CCc2ccc(CNS(=O)(=O)CCCF)cc2C1Cc1ccccc1.O=C(O)C(F)(F)F>>NC1CCc2ccc(CNS(=O)(=O)CCCF)cc2C1Cc1ccccc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20020002161A1,CC(C)(C)OC(=O)N1CCc2c(C=O)c3ccccc3n2CC1.NO>>N#Cc1c2n(c3ccccc13)CCNCC2,,O=CO,,Cl,,test
US20050065066A1,O=C(O)c1ccc(-c2ccc(CBr)cc2)cc1.c1ccc(C(c2ccccc2)(c2ccccc2)n2nnc(-c3ccc4[nH]ccc4c3)n2)cc1>>O=C(O)c1ccc(-c2ccc(Cn3ccc4cc(-c5nn[nH]n5)ccc43)cc2)cc1,,C1CCOC1,CN(C)C=O,O,[H-].[Na+],test
US20140171423A1,CC[Si](Cl)(CC)CC.COC(=O)[C@@H]1C[C@@H](O)CN1CCC#N>>CC[Si](CC)(CC)O[C@@H]1C[C@H]2C(=O)NCCCN2C1,,CN(C)C=O,,c1c[nH]cn1,,test
US20070265286A1,COc1cc2c(Cl)ncnc2cc1OCC1CCN(C)CC1.Cc1ccc(N)c(F)c1>>COc1cc2c(Nc3ccc(C)cc3F)ncnc2cc1OCC1CCN(C)CC1,,CC(C)O,,Cl,,test
US04757081,CC(C(=O)CC(=O)c1ccccc1F)C(=O)c1ccccc1Cl.Nc1ccccc1>>Cc1c(-c2ccccc2Cl)n(-c2ccccc2)c(-c2ccccc2F)cc1=O,,Cc1ccccc1C,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20030007927A1,CCOC(=O)Cn1nnnc1C(C)(C)CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1>>CC(C)(CCCCOc1cc(-c2ccccc2)cc(-c2ccccc2)n1)c1nnnn1CC(=O)O,,C1CCOC1,,[Li+].[OH-],,test
US20120238569A1,COC(=O)c1sc(C)cc1C#N.O=C1CCC(=O)N1Br>>COC(=O)c1sc(CBr)cc1C#N,,ClC(Cl)(Cl)Cl,,,,test
US20150239900A1,COC(=O)c1cc(Br)c(Cl)cc1N.OB(O)c1ccccc1Cl>>COC(=O)c1cc(-c2ccccc2Cl)c(Cl)cc1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20040010009A1,CC(C)(C)OC(=O)N1CCC(O)CC1.O=[N+]([O-])c1ccc(O)c(F)c1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc([N+](=O)[O-])cc2F)CC1,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100035918A1,CC[N+](=O)[O-].O=Cc1ccc2ncnn2c1>>CC(C(O)c1ccc2ncnn2c1)[N+](=O)[O-],,CO,,C[O-].[Na+],,test
US20160185785A1,CNC(=O)Cl.O=C(c1ccc(F)cc1)N1CCC(O)(Cn2cnc3c(ccn3C3CCNCC3)c2=O)CC1>>CNC(=O)N1CCC(n2ccc3c(=O)n(CC4(O)CCN(C(=O)c5ccc(F)cc5)CC4)cnc32)CC1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20080214833A1,COc1ccccc1OCCN.O=C(O)c1ccccc1O.c1ccc2c(c1)[nH]c1cccc(OCC3CO3)c12>>COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12.O=C([O-])c1ccccc1O,,CC(C)O,,,,test
US20120022109A1,CNCC(=O)OC(C)(C)C.N#Cc1ccc(CBr)c(F)c1>>CN(CC(=O)OC(C)(C)C)Cc1ccc(C#N)cc1F,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US05708008,CN1CCC(=O)CC1.Nc1ccc2[nH]ccc2c1>>CN1CC=C(c2c[nH]c3ccc(N)cc23)CC1,,CO,O,[K+].[OH-],,test
US20060030585A1,N#C[Cu].O=C(N1C2CCC1CC(=C1c3ccccc3Oc3cc(Br)ccc31)C2)C(F)(F)F>>N#Cc1ccc2c(c1)Oc1ccccc1C2=C1CC2CCC(C1)N2C(=O)C(F)(F)F,,CN(C)C=O,,O,,test
US20050282891A1,C[C@@H](O)CO[Si](C)(C)C(C)(C)C.O=C(O)c1ccccc1OCc1ccccc1>>C[C@H](CO[Si](C)(C)C(C)(C)C)OC(=O)c1ccccc1OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20160068489A1,CCCCCCCCCCCC(=O)Nc1nc(C)c(OCc2ccccc2)c(C)c1C>>CCCCCCCCCCCC(=O)Nc1nc(C)c(O)c(C)c1C,[Pd],,,CO,,test
US06235736B1,COc1ccc(N)cc1O.O=C1CCCC(=O)C1>>COc1ccc(NC2=CC(=O)CCC2)cc1O,Cc1ccc(S(=O)(=O)O)cc1,c1ccccc1,,,,test
US20060178350A1,O=C1CCCC2(C=CCCC2)C1.OCCO>>C1=CC2(CCC1)CCCC1(C2)OCCO1,,Cc1ccccc1,,,,test
US20130196974A1,Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(NC3CCNC3)c2c1.O=C1COC1>>Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(NC3CCN(C4COC4)C3)c2c1,,C1CCOC1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160068559A1,CC(C)NC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21.O=CCCCC(=O)OCc1ccccc1>>CC(C)N(CCCCC(=O)OCc1ccccc1)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21,,CO,ClCCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070238718A1,CC(=O)Nc1nc2c(s1)-c1c(c(C3CC3)nn1-c1ccc([N+](=O)[O-])cc1Cl)CC2>>CC(=O)Nc1nc2c(s1)-c1c(c(C3CC3)nn1-c1ccc(N)cc1Cl)CC2,[Fe],CC(=O)O,,,,test
US04849327,O=[N+]([O-])O.O=[N+]([O-])c1ccc(Cl)cc1Cl>>O=[N+]([O-])c1cc([N+](=O)[O-])c(Cl)cc1Cl,,O=S(=O)(O)O,,,,test
US20120035208A1,CC(=O)Nc1cccc(B2OC(C)(C)C(C)(C)O2)c1.Cn1ncc2c(Cl)cc(-c3cccc4[nH]ncc34)nc21>>CC(=O)Nc1cccc(-c2cc(-c3cccc4[nH]ncc34)nc3c2cnn3C)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,O,O=C([O-])[O-].[Na+].[Na+],,test
US20080096906A1,CC(C)Nc1ccccc1F.O=C(O)c1nccn1Cc1ccccc1>>CC(C)N(C(=O)c1nccn1Cc1ccccc1)c1ccccc1F,,ClCCl,,O,O=C([O-])O.[Na+],test
US04431793,CC(C)(c1ccc(O)cc1)c1ccc(O)cc1.O.O=C(Cl)Cl.[OH-]>>CC(C)(c1ccc(O)cc1)c1ccc(O)cc1.O=C(O)O,,ClCCl,O,CCN(CC)CC,,test
US20130296329A1,COCc1cc(-n2ccnc2C2CCOC2)c(N)cc1C(=O)OC.O=C(n1ccnc1)n1ccnc1>>COCc1cc2c(cc1C(=O)OC)[nH]c(=O)c1cnc(C3CCOC3)n12,,Clc1ccccc1Cl,,,,test
US04792551,Cc1ccc(S(=O)(=O)OCCCl)cc1.O=C1c2ccccc2Cc2ccccc21>>ClCCOc1c2ccccc2cc2ccccc12,,CN(C)C=O,,CCOCC,O=C([O-])[O-].[K+].[K+],test
US05221799,CCCC(F)(F)C(CCC[C@H]1[C@H](OC2CCCCO2)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)OC)O[Si](C)(C)C(C)(C)C>>CCCC(F)(F)C(O)CCC[C@H]1[C@H](OC2CCCCO2)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)OC,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110245477A1,C=CCCC(=O)O.Oc1ccccc1>>C=CCCC(=O)Oc1ccccc1,,ClCCl,,CCN(CC)CC,O=S(Cl)Cl,test
US20080194549A1,c1ccc(CNCC2CC2)cc1>>c1ccc(CNC2CC2)cc1,,CO,ClCCl,,,test
US20040122016A1,COC(=O)Cc1cccc(OCCCl)c1>>O=C(O)Cc1cccc(OCCCl)c1,,CO,,Cl,[Na+].[OH-],test
US20070179161A1,CC(C)(C)OC(=O)N(c1ccc(F)cc1)c1cc(-c2ccccc2)nc2ccnn12.Cl>>Cl.Fc1ccc(Nc2cc(-c3ccccc3)nc3ccnn23)cc1,,CO,,,,test
US06114325,CCCCCCCCCCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCN(C(C)C)C(C)C.Cl>>CCCCCCCCCCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCN(C(C)C)C(C)C.Cl,,CCOC(C)=O,,,,test
US20070135623A1,BrBr.CC1C(=O)c2sccc2C1C>>CC1C(=O)c2scc(Br)c2C1C,,ClC(Cl)Cl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20150051409A1,CCOC(=O)C1(C(=O)OCC)c2ccsc2C(C(=O)OCC)(C(=O)OCC)c2ccsc21>>O=C(O)c1c2c(c(C(=O)O)c3sccc13)CCS2,,CO,,Cl,[K+].[OH-],test
US20140275172A1,CCCc1cc2cc(C(C)(F)F)cc(COc3ccc(CCC(=O)OCC)c(C)c3C)c2o1>>CCCc1cc2cc(C(C)(F)F)cc(COc3ccc(CCC(=O)O)c(C)c3C)c2o1,,O,,C1CCOC1,[Li+].[OH-],test
US20110263598A1,COCCBr.O=C1Nc2ccccc2C1=O>>COCCN1C(=O)Cc2ccccc21,,CN(C)C=O,CS(C)=O,Cl,[H-].[Na+],test
US20120101064A1,CNC.O=C(O)c1cccc2[nH]cnc12>>CN(C)C(=O)c1cccc2[nH]cnc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20120101123A1,COC(OC)N(C)C.Cc1c(Br)cncc1[N+](=O)[O-]>>CN(C)/C=C/c1c(Br)cncc1[N+](=O)[O-],,CCOC(C)=O,CN(C)C=O,,,test
US20130303515A1,Cc1cc(C)cc(CC(=O)N2CCC2(C)C(=O)N(CCC(=N)NO)Cc2ccc(Cl)cc2)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>Cc1cc(C)cc(CC(=O)N2CCC2(C)C(=O)N(CCc2noc(O)n2)Cc2ccc(Cl)cc2)c1,,C1COCCO1,,,,test
US20150315126A1,NC(=O)c1ccc(N2CCOCC2)c(N)c1.O=C(Cl)OCc1ccccc1>>NC(=O)c1ccc(N2CCOCC2)c(NC(=O)OCc2ccccc2)c1,,C1CCOC1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150175623A1,COCCl.O=Cc1ccc(F)cc1O>>COCOc1cc(F)ccc1C=O,,CCOC(C)=O,,CC(C)=O,,test
US20070161615A1,CC(=O)N[C@H]1CCN(c2ccc([N+](=O)[O-])cc2)C1>>CC(=O)N[C@H]1CCN(c2ccc(N)cc2)C1,,CCO,,,,test
US20110159019A1,CC(C)(C)OC(=O)N[C@@H]1C[C@@H](CO)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N[C@@H]1C[C@@H](COS(C)(=O)=O)C1,,CCOC(C)=O,ClCCl,,,test
US04374980,COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1.ICCOCCI>>COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N2CCOCC2)[C@H](O)[C@H](C)O1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20070021489A1,CC(=O)OC(C)=O.CC(=O)c1ccc(O)c([N+](=O)[O-])c1>>CC(=O)Nc1cc(C(C)=O)ccc1O,[Pd],CN(C)C=O,CO,,,test
US20110190353A1,COCc1cccc(C(=O)N(C)OC)c1.Cn1cnnn1>>COCc1cccc(C(=O)c2nnnn2C)c1,,C1CCOC1,,CC(C)[Mg]Cl,Cl,test
US20070265269A1,C#CCO.O=C(O)c1ccccc1>>C#CCOC(=O)c1ccccc1,,Cc1ccccc1,,O=S(=O)(O)O,,test
US20150299188A1,COC(=O)c1ccc(O[Si](C)(C)C(C)(C)C)cc1N1Cc2ccccc2NC1=O>>COC(=O)c1ccc(O)cc1N1Cc2ccccc2NC1=O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20060252750A1,CCOC(=O)CN1CCC(C2CCNCC2)CC1.O=C(O)[C@@H](Cc1cc(Br)c(O)c(Br)c1)OC(=O)N1CCC(N2CCc3ccccc3NC2=O)CC1>>CCOC(=O)CN1CCC(C2CCN(C(=O)[C@@H](Cc3cc(Br)c(O)c(Br)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US05922717,O=C(O)C=Cc1ccncc1>>O=C(O)CCC1CCNCC1,O=[Pt]=O,CC(=O)O,,[H][H],,test
US03935182,CN(C)CCCNC=O.O=[N+]([O-])c1cccc2c(CCl)cccc12>>C[N+](C)(CCCNC=O)Cc1cccc2c([N+](=O)[O-])cccc12.[Cl-],,O,,,,test
US20110178064A1,CC(C)(C)[Si](OCc1ccc(F)nc1F)(c1ccccc1)c1ccccc1.O=C=O>>CC(C)(C)[Si](OCc1cc(C(=O)O)c(F)nc1F)(c1ccccc1)c1ccccc1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20160244441A1,CNc1ccn2cc(-c3ccc(O)cc3)nc2c1.FCCBr>>CNc1ccn2cc(-c3ccc(OCCF)cc3)nc2c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US03931281,CC(C)COC(=O)Cl.CCCCC[C@H](O)/C=C/[C@H]1C=CC(=O)[C@@H]1C/C=C\CCCC(=O)O>>Oc1ccc(-c2ccccc2)cc1,,CCN(CC)CC,,,,test
US20150232460A1,COc1ccc(COC2CC=CC2)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(COC2CC3OC3C2)cc1,,ClCCl,,,,test
US04874769,N#CCCCl.Oc1ccc(O)cc1>>N#CCCOc1ccc(O)cc1,,CN(C)C=O,O,C1CCOC1,[Na+].[OH-],test
US20140275064A1,CN(C)/C=N/c1ccc2nc(C#N)sc2c1C#N.Nc1ccc2[nH]cnc2c1>>N#Cc1nc2ccc3ncnc(Nc4ccc5nc[nH]c5c4)c3c2s1,,CO,ClCCl,[Br-].[K+],,test
US20100087484A1,CN1CCC(Cl)CC1.O=S(=O)(c1cccc(O)c1)n1ccc2ccccc21>>CN1CCC(Oc2cccc(S(=O)(=O)n3ccc4ccccc43)c2)CC1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05755994,CCCOC[C@@H]1CC[C@@H](c2ccc(C(=O)O)cc2)CC1.O=S(Cl)Cl>>CCCOC[C@@H]1CC[C@@H](c2ccc(C(=O)Cl)cc2)CC1,,Cc1ccccc1,,c1ccncc1,,test
US20150175557A1,CC1(C)C(N)CCCC1O.CSc1ncc(C#N)c(Cl)n1>>CSc1ncc(C#N)c(NC2CCCC(O)C2(C)C)n1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20110077240A1,COCCOCCOCCN(Cc1ccc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)cc1)C(C)=O.Cc1cc(N)no1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COCCOCCOCCN(Cc1ccc(-c2cc3nccc(Oc4ccc(NC(=O)Nc5cc(C)on5)cc4F)c3s2)cc1)C(C)=O,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20110319449A1,CCS.COc1cc(-n2ccc(-c3ccc(C(F)(F)F)cc3)cc2=O)ccc1OC[C@H]1CO1>>CCSC[C@@H](O)COc1ccc(-n2ccc(-c3ccc(C(F)(F)F)cc3)cc2=O)cc1OC,,C1CCOC1,CCOC(C)=O,[K+].[OH-],,test
US06391916B1,C#CCCCCC#CC(O)/C(Br)=C/c1ccccc1.CI>>C#CCCCCC#CC(OC)/C(Br)=C/c1ccccc1,,CS(C)=O,,[K+].[OH-],,test
US20060111375A1,COc1cc2c(Oc3cc4ccccc4nc3C)ccnc2cc1OCCCCl.c1c[nH]cn1>>COc1cc2c(Oc3cc4ccccc4nc3C)ccnc2cc1OCCCn1ccnc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US06936602B1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3Cc2nnn(C)n2)cc1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3Cc2nnn(C)n2)cc1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20100168145A1,COC(OC)N(C)C.COc1ccc2c(c1)CCC21CCCC(CN)N1>>COc1ccc2c(c1)CCC21CCCC2CN=CN21,,ClCCl,,,,test
US20120329826A1,C[C@@H](Oc1c([N+](=O)[O-])nc(Cl)c2c1ccn2S(=O)(=O)c1ccccc1)c1c(Cl)ccc(F)c1Cl>>C[C@@H](Oc1c(N)ncc2c1ccn2S(=O)(=O)c1ccccc1)c1c(Cl)ccc(F)c1Cl,[Zn],C1COCCO1,CCOC(C)=O,Cl,O=C([O-])O.[Na+],test
US06143764,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.Nc1ccc(F)c(F)c1F.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccc(F)c(F)c4F)cc3)c2cc1OC,,CCN(CC)CC,Cc1ccccc1,O=C([O-])O.[Na+],,test
US20160107997A1,CN(C)CCN(Cc1ccccc1)C(=O)CNc1cccc2c1CN(C(=O)OC(C)(C)C)C2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CN(C)CCN(Cc1ccccc1)C(=O)CN(C(=O)C(F)(F)F)c1cccc2c1CN(C(=O)OC(C)(C)C)C2,,ClCCl,,,,test
US20060293303A1,O=C(Cl)OCc1ccccc1.c1cc(C2CCNCC2)ccn1>>O=C(OCc1ccccc1)N1CCC(c2ccncc2)CC1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US05385692,CCCCCCCCCCc1ccc(-c2ccc(O)cc2)cc1.O=S(=O)(O)C(F)(F)F>>CCCCCCCCCCc1ccc(-c2ccc(OS(=O)(=O)C(F)(F)F)cc2)cc1,,c1ccncc1,,,,test
US20120058984A1,CSc1nc(Cl)cc(Cc2ccccc2)n1.N>>CSc1nc(N)cc(Cc2ccccc2)n1,,CC(C)O,,,,test
US05686459,CC1C2C(=O)N(Cc3ccccc3)C(=O)C2C(c2ccc(C#N)cc2)N1C.NO>>CC1C2C(=O)N(Cc3ccccc3)C(=O)C2C(c2ccc(C(N)=NO)cc2)N1C,,CN(C)C=O,,Cl,[H-].[Na+],test
US20040162279A1,CC1OC(C)C2N(C1=O)c1ccc(NC(=O)OC(C)(C)C)cc1CC21C(=O)NC(=O)NC1=O.Cl>>CC1OC(C)C2N(C1=O)c1ccc(N)cc1CC21C(=O)NC(=O)NC1=O.Cl,,ClCCl,,C1COCCO1,,test
US20150291563A1,COC(=O)C(=O)C=Cc1ccc(Br)s1.NNc1ccc(F)cc1F>>COC(=O)C1=NN(c2ccc(F)cc2F)C(c2ccc(Br)s2)C1,,CC(=O)O,,Cl,,test
US04687775,Nc1ncccc1CO.O=C(CBr)c1ccccc1>>OCc1cccn2cc(-c3ccccc3)nc12,,CCO,,,,test
US20080253965A1,BrCCCBr.CN(C)C=O.Nc1nc(F)nc2nc(Cc3cc4c(cc3I)OCO4)[nH]c12>>CC(C)NCCCn1c(Cc2cc3c(cc2I)OCO3)nc2c(N)nc(F)nc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140005183A1,CCOC=O.C[Si](C)(C)CCOCn1cc(I)c2c(Cl)ncnc21>>C[Si](C)(C)CCOCn1c(C=O)c(I)c2c(Cl)ncnc21,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20050085508A1,C=CCCCBr.COC(=O)C(CCC1(CCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)CCCCC1)C(=O)OC>>C=CCCCC(CCC1(CCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)CCCCC1)(C(=O)OC)C(=O)OC,,CN(C)C=O,O,Cl,CC(C)(C)[O-].[K+],test
US04246429,Cc1ccccc1N.O=C(Cl)c1c(Cl)cccc1Cl>>Cc1ccccc1NC(=O)c1c(Cl)cccc1Cl,CN(C)c1ccncc1,ClC(Cl)Cl,,,,test
US04451476,Cc1cc(CCCCCCCOc2ccc(C#N)cc2)on1.OO>>Cc1cc(CCCCCCCOc2ccc(C(N)=O)cc2)on1,,CCO,,O=S(=O)(O)O,[Na+].[OH-],test
US20070060754A1,CCCNc1c(NC(=O)COCC)cnc2ccc(OCc3ccccc3)cc12>>CCCn1c(COCC)nc2cnc3ccc(OCc4ccccc4)cc3c21,,CCO,,CCN(CC)CC,Cl,test
US20160165886A1,COC(=O)c1ccc(Cl)c2c1C=CC(C)(C)O2>>CC1(C)C=Cc2c(CO)ccc(Cl)c2O1,,CCOCC,,,,test
US20100210680A1,CC(C)(C)OC(=O)N1C[C@H]2c3cccc(O)c3CO[C@@]2(C)C1.ICC1CC1>>CC(C)(C)OC(=O)N1C[C@H]2c3cccc(OCC4CC4)c3CO[C@@]2(C)C1,,CN(C)C=O,,[H-].[Na+],,test
US04212796,COc1cc(OC)cc(C(C)(C)OC(=O)N[C@@H](CSC(c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)N[C@H](C(=O)N[C@@H](COC(C)(C)C)C(=O)O)[C@@H](C)OC(C)(C)C)c1.O=C(O)C(F)(F)F>>C[C@@H](OC(C)(C)C)[C@H](NC(=O)[C@@H](N)CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N[C@@H](COC(C)(C)C)C(=O)O.O=C(O)C(F)(F)F,,ClCCl,O,c1ccncc1,,test
US20140309193A1,COc1ccc(-n2c(C(=O)OC(C)C)c(OCc3ccccc3)c(OCc3ccccc3)c2C(=O)N(C)C)cc1>>COc1ccc(-n2c(C(=O)OC(C)C)c(O)c(O)c2C(=O)N(C)C)cc1,[Pd],CO,,,,test
US04060603,CCOC(=O)C1(C(=O)OCC)NC=CC1CC>>CC[C@@H]1CCN[C@H]1C(=O)O,,CCO,,Cl,[Na+].[OH-],test
US20080255083A1,O=c1cc(OCc2ccccc2)cc[nH]1.OCc1ccc(CCI)cc1>>O=c1cc(OCc2ccccc2)ccn1CCc1ccc(CO)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05624935,O=C1SC(Cc2ccc(O)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1.OCc1cn2ccccc2n1>>O=C1SC(Cc2ccc(OCc3cn4ccccc4n3)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1,,c1ccccc1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20110034455A1,CCOC(=O)C(C)C1CC2(CCN(C(=O)OC(C)(C)C)CC2)c2c(Br)cccc21>>CCOC(=O)C(C)C1CC2(CCNCC2)c2c(Br)cccc21,,O=C(O)C(F)(F)F,,,,test
US06342498B1,COc1ccccc1N1CCNCC1.O=C1c2ccccc2C(=O)N1CCBr>>COc1ccccc1N1CCN(CCN2C(=O)c3ccccc3C2=O)CC1,,CC#N,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100317568A1,CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)Nc1ccc(C2CCC(c3ccc(-c4c[nH]c([C@@H]5CCCN5C(=O)OC(C)(C)C)n4)cc3)N2c2ccc(C(C)(C)C)cc2)cc1.Cl>>CC(C)(C)c1ccc(N2C(c3ccc(NC(=O)[C@H]4CCCN4)cc3)CCC2c2ccc(-c3c[nH]c([C@@H]4CCCN4)n3)cc2)cc1.Cl,,C1COCCO1,,,,test
US20130336920A1,CC(C)(C)OC(=O)CCSCc1cccc(C(=O)O)c1.Nc1ccc(Cl)cc1-c1cc(C(=O)NCc2cccc(C(F)(F)F)c2)ccn1>>CC(C)(C)OC(=O)CCSCc1cccc(C(=O)Nc2ccc(Cl)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US09044478B2,CC(C)CN(CCCN1CCN(CCCNc2nc3ccccc3[nH]2)CC1)CC(C)C.Cc1ccc(N=C=S)c([N+](=O)[O-])c1>>Cc1ccc(NC(=S)NCCCN2CCN(CCCN(CC(C)C)CC(C)C)CC2)c([N+](=O)[O-])c1,,ClCCl,,[Na+].[OH-],,test
US20090306103A1,COc1cc2nccc(O)c2cc1OC.O=[N+]([O-])c1ccc(F)cc1>>COc1cc2nccc(Oc3ccc([N+](=O)[O-])cc3)c2cc1OC,,CC#N,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080207654A1,CCCc1nc(CC)n(-c2ccc(C(C)(C)O)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.CI>>CCCc1nc(CC)n(-c2ccc(C(C)(C)OC)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20120035132A1,CC(C)OCCOc1nc(Cl)c(C2CC2)cc1C#N.OB1OCc2cc(O)ccc21>>CC(C)OCCOc1nc(Oc2ccc3c(c2)COB3O)c(C2CC2)cc1C#N,,CS(C)=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20160051529A1,CCOC(=O)[C@@H](Cc1ccc(OCC(=O)c2cccc(OC)c2)cc1)OCC>>CCO[C@H](Cc1ccc(OCC(=O)c2cccc(OC)c2)cc1)C(=O)O,,CO,,Cl,[Li+].[OH-],test
US20070244155A1,COC(=O)CC1COCc2cc(OCc3ccc(OC)cc3)ccc21>>COC(=O)CC1COCc2cc(O)ccc21,[Pd],CO,,,,test
US06399612B1,COC(=O)CCC(=O)c1ccc(Br)cc1.OB(O)c1ccc(Cl)s1>>COC(=O)CCC(=O)c1ccc(-c2ccc(Cl)s2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20060128695A1,COc1cc2c(cc1OC)C(c1cccc(C#N)c1)=NCC(=O)N2.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>COc1cc2c(cc1OC)C(c1cccc(C#N)c1)=NCC(=S)N2,,c1ccncc1,,[Cl-].[Na+],,test
US20090264445A1,CC(C)C[C@@H](C(=O)O)N1CC(Oc2cccc(C(C)(C)O)c2F)=CC1=O.Cn1ccc(N)n1>>CC(C)C[C@@H](C(=O)Nc1ccn(C)n1)N1CC(Oc2cccc(C(C)(C)O)c2F)=CC1=O,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20040209905A1,CCCNC(=O)Nc1ccc(Oc2ncnc3cc(OCCCBr)c(OC)cc23)cc1Cl.Sc1ccncc1>>CCCNC(=O)Nc1ccc(Oc2ncnc3cc(OCCCSc4ccncc4)c(OC)cc23)cc1Cl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110263598A1,C#Cc1ccc(C=O)cc1.C1CCNC1>>C#Cc1ccc(N2CCCC2)cc1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04002757,NC1CCN(C2CCCCC2)C1.O=C(Cl)c1cccc2ccccc12>>O=C(NC1CCN(C2CCCCC2)C1)c1cccc2ccccc12,,ClC(Cl)Cl,,,,test
US05000775,CC(C)(C)Nc1nc(C(F)(F)F)c(C(=O)Cl)o1.NCCO>>CC(C)(C)Nc1nc(C(F)(F)F)c(C(=O)NCCO)o1,,ClCCl,,CCN(CC)CC,,test
US20030055085A1,Fc1ccc(-c2c[nH]cn2)nc1.N#Cc1cccc(F)c1>>N#Cc1cccc(-n2cnc(-c3ccc(F)cn3)c2)c1,,ClC(Cl)Cl,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20010044435A1,O=C1CC2(CCO1)CCN(C(=O)OCc1ccccc1)CC2>>O=C1CC2(CCNCC2)CCO1,[Pd],CCO,,,,test
US20030119844A1,CO.COc1cc(OC(F)(F)F)ccc1-c1nc(Cl)c([N+](=O)[O-])cc1C>>COc1cc(OC(F)(F)F)ccc1-c1nc(OC)c([N+](=O)[O-])cc1C,,CO,,C[O-].[Na+],,test
US20110213143A1,CC(C)(C)OC(=O)NCCC[C@@H](Cc1ncn2c1CCc1ccccc1-2)C(=O)O.CC(I)OC(=O)OC1CCCCC1>>CC(OC(=O)OC1CCCCC1)OC(=O)[C@@H](CCCNC(=O)OC(C)(C)C)Cc1ncn2c1CCc1ccccc1-2,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20090054648A1,CC(C)(C)OC(=O)NC1(C)CN(Cc2ccccc2)C(=O)C12CC2>>CC1(N)CN(Cc2ccccc2)C(=O)C12CC2,,Cc1ccccc1,,Cl,O,test
US04282365,COC(=O)c1ccc2c(c1)Cc1ccccc1CO2>>O=C(O)c1ccc2c(c1)Cc1ccccc1CO2,,CCO,O,Cl,[Na+].[OH-],test
US20090069288A1,CC1(C)OCC(COc2ccc(NC(=O)c3nc(C(Cl)(Cl)Cl)n(-c4ccccc4)n3)c(Cl)c2)O1>>O=C(Nc1ccc(OCC(O)CO)cc1Cl)c1nc(C(Cl)(Cl)Cl)n(-c2ccccc2)n1,,CO,O,Cl,,test
US20040009979A1,C[C@@](O)(C(=O)Nc1ccc(S(=O)(=O)c2ccccc2F)cc1Cl)C(F)(F)F.C[S-]>>CSc1ccccc1S(=O)(=O)c1ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c(Cl)c1,,CN1CCCC1=O,,[Cl-].[NH4+],,test
US20030069312A1,C[N+](=O)[O-].Cc1ccccc1CC(=O)Nc1ccc(C(=O)O)c(Cl)c1>>Cc1ccccc1CC(=O)Nc1ccc(C(=O)C[N+](=O)[O-])c(Cl)c1,,CN(C)C=O,,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US06593326B1,CC(C)N.O=C(Cl)c1cnc(Cl)nc1Cl>>CC(C)NC(=O)c1cnc(Cl)nc1Cl,,C1CCOC1,,CCN(CC)CC,,test
US06537948B1,COC(=O)COc1ccc(OC(C)=O)cn1>>COC(=O)COc1ccc(O)cn1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20150376160A1,CCOC(=O)C1(c2ccc(-c3ccc(-c4sc(F)cc4C(=O)O)cc3)cc2)CC1.C[C@@H](O)c1ccc(F)cc1F.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4sc(F)cc4NC(=O)O[C@H](C)c4ccc(F)cc4F)cc3)cc2)CC1,,Cc1ccccc1,,CCN(CC)CC,[Cl-].[NH4+],test
US20020128290A1,COC(=O)c1ccc(OC)c(O)c1.O=C1CCCCC1Cl>>COC(=O)c1ccc(OC)c(OC2CCCCC2=O)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05629406,CCOC(=O)CBr.O=C(Nc1ccc(O)cc1)OCc1ccccc1>>CCOC(=O)COc1ccc(NC(=O)OCc2ccccc2)cc1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20070037794A1,CC(C)(C)c1ccc(S(=O)(=O)Nc2cc(Cl)cnc2C(=O)c2cccc(N)n2)cc1.CS(=O)(=O)Cl>>CC(C)(C)c1ccc(S(=O)(=O)Nc2cc(Cl)cnc2C(=O)c2cccc(NS(C)(=O)=O)n2)cc1,,c1ccncc1,,,,test
US20040157859A1,COc1ccc(C2CC(=O)N(c3cccc(C(N)=O)c3)C2)cc1OCc1ccccc1>>COc1ccc(C2CC(=O)N(c3cccc(C(N)=O)c3)C2)cc1O,[Pd],CCO,,,,test
US04778931,CCCCCC(O)c1cccc(O)c1.ICC1CCc2ccccc2C1>>CCCCCC(O)c1cccc(OCC2CCc3ccccc3C2)c1,,C1CCOC1,CS(C)=O,O,[Na+].[OH-],test
US05496834,COC(=O)[C@H](CCCO)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1>>O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCOC1=O)OCc1ccccc1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20150005304A1,Cc1cc(C(=O)Cl)ccc1OC(C)C.O=C1C=COC2(CCNCC2)C1>>Cc1cc(C(=O)N2CCC3(CC2)CC(=O)C=CO3)ccc1OC(C)C,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20160108036A1,CCOC(=O)c1cn(Cc2ccc(Cn3cccn3)cc2)nc1N>>Nc1nn(Cc2ccc(Cn3cccn3)cc2)cc1C(=O)O,,CCO,,[Na+].[OH-],,test
US20100234346A1,Cc1cc(C(N)=O)nc(NC(C)C)n1>>Cc1cc(C#N)nc(NC(C)C)n1,,ClCCl,,c1ccncc1,,test
US20120035196A1,COCOc1cc(C)c(-c2cccc(COc3ccc4c(c3)OC3(CC3)C4CC(=O)OC)c2C)c(C)c1>>COC(=O)CC1c2ccc(OCc3cccc(-c4c(C)cc(O)cc4C)c3C)cc2OC12CC2,,C1CCOC1,CO,Cl,O,test
US08653089B2,C[Mg]Br.O=Cc1nc2cnccc2n1-c1ccccc1>>CC(O)c1nc2cnccc2n1-c1ccccc1,,C1CCOC1,,[Cl-].[NH4+],,test
US07592362B2,CC(C)COC(=O)Cl.Cc1cccc([C@H](C)c2ncc[nH]2)c1C>>Cc1cccc([C@H](C)c2nccn2C(=O)OCC(C)C)c1C,,ClCCl,,CCN(CC)CC,,test
US09150557B1,OC1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>OC[C@H](OCc1ccccc1)[C@@H](OCc1ccccc1)[C@H](OCc1ccccc1)[C@H](O)COCc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100210680A1,CCOC(=O)Cl.C[C@]12CNC[C@H]1c1cccc(Cl)c1CO2>>CCOC(=O)N1C[C@H]2c3cccc(Cl)c3CO[C@@]2(C)C1,,C1CCOC1,O,O=C([O-])O.[Na+],,test
US20100261710A1,O=C(O)c1cn2c3c(cccc13)CCC2.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>O=C=Nc1cn2c3c(cccc13)CCC2,,Cc1ccccc1,,CCN(CC)CC,,test
US04900727,COc1cc(OC)c(C2CCN(C)CC2=O)c(OC)c1>>COc1cc(OC)c([C@H]2CCN(C)C[C@H]2O)c(OC)c1,,CCO,O,[BH4-].[Na+],,test
US04200588,CSCc1cc(OC23CC4CC(CC(C4)C2)C3)cc(C)c1N>>Cc1cc(OC23CC4CC(CC(C4)C2)C3)cc(C)c1N,[Ni],,,,,test
US20130165464A1,COc1ccc(CN(C(=O)C2CC2)c2cc(-n3cc(-c4ccccc4Cl)c(-c4nccn4COCC[Si](C)(C)C)c3)c(C)cn2)c(OC)c1>>Cc1cnc(NC(=O)C2CC2)cc1-n1cc(-c2ncc[nH]2)c(-c2ccccc2Cl)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050119345A1,CCOC(=O)[C@]1(N)[C@H](OCc2cccc([N+](=O)[O-])c2)C[C@@H]2[C@H]1[C@@]2(F)C(=O)OCC>>CCOC(=O)[C@]1(N)[C@H](OCc2cccc(N)c2)C[C@@H]2[C@H]1[C@@]2(F)C(=O)OCC,[Zn],CC(=O)O,,,,test
US20110217311A1,COC(=O)c1sc2ncnc(Nc3ccc(F)cc3OC3CCC(F)(F)CC3)c2c1C>>Cc1c(C(=O)O)sc2ncnc(Nc3ccc(F)cc3OC3CCC(F)(F)CC3)c12,,C1CCOC1,CO,[Na+].[OH-],,test
US20160039865A1,C[C@]12CC[C@H](O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](c3ccc(=O)oc3)CC[C@]12O>>C[C@]12CCC(=O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](c3ccc(=O)oc3)CC[C@]12O,,CC(C)=O,,O=S([O-])O.[Na+],,test
US20070191603A1,COC(=O)c1ccc(N)c(C)c1.COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccc(C(=O)O)cc3C)cc21>>COC(=O)c1ccc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cc(Cl)ccc2OC)CCO3)c(C)c1,,CN(C)C=O,Cc1ccccc1,O=S(Cl)Cl,,test
US20070254931A1,CC(=O)Nc1nc(-c2ccc(CCC(=O)O)cc2)c(Cc2ccc(S(C)(=O)=O)cc2)s1.CC(C)(C)O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(=O)Nc1nc(-c2ccc(CCNC(=O)OC(C)(C)C)cc2)c(Cc2ccc(S(C)(=O)=O)cc2)s1,,CCOC(C)=O,,CCN(CC)CC,,test
US20120122780A1,CCOC(=O)C(C)(C)Sc1ccnn1-c1cccc2ccccc12>>CC(C)(Sc1ccnn1-c1cccc2ccccc12)C(=O)O,,CO,,[Na+].[OH-],,test
US20080021026A1,COc1nccc(Nc2ccc3sc(-c4ccnc(N)n4)c(C)c3c2)n1>>Cc1c(-c2ccnc(N)n2)sc2ccc(Nc3ccnc(O)n3)cc12,,ClCCl,,BrB(Br)Br,,test
US20160108016A1,CCOC(=O)C(C)(C)c1cc(O)c(-c2cc(C)cc(C)c2)c(OC)c1.CCOC(=O)C(C)(C)c1cc(OC)c(-c2cc(C)cc(C)c2)c(OC)c1>>CCOC(=O)C(C)(C)c1cc(O)c(-c2cc(C)cc(C)c2)c(O)c1.CCOC(=O)C(C)(C)c1cc(O)c(-c2cc(C)cc(C)c2)c(OC)c1,,ClCCl,,BrB(Br)Br,,test
US20070021454A1,CCCC[Sn](CCCC)CCCC.COC(=O)c1cccc(Br)c1>>C=CCc1cccc(C(=O)OC)c1,,CN(C)C=O,,O,,test
US04555513,CI.COC(=O)C(C)c1ccc2c(c1)C=CC(C)(C)N2>>COC(=O)C(C)c1ccc2c(c1)C=CC(C)(C)N2C,,CCOCC,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20160272621A1,CC1(COc2ccncc2[N+](=O)[O-])CC1>>CC1(COc2ccncc2N)CC1,[Pd],CCO,,,,test
US20070043065A1,CCOC(OCC)OCC.Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccccc1N>>Cc1ccc(C(=O)NC2CC2)cc1-n1cnc2ccccc2c1=O,,CCO,,CC(=O)O,,test
US20070066588A1,C[C@@H]1CCCN1[C@@H]1C[C@@H](c2nc3ccc(Br)cc3s2)C1.O=c1cccn[nH]1>>C[C@@H]1CCCN1[C@@H]1C[C@@H](c2nc3ccc(-n4ncccc4=O)cc3s2)C1,[Cu],c1ccncc1,,O=C([O-])[O-].[K+].[K+],,test
US20130267499A1,COc1ccc(CN(c2ncc(F)cn2)c2nc3c(s2)CCN(CC2CCCC2)c2nn(Cc4ccc(OC)cc4)cc2-3)cc1>>Fc1cnc(Nc2nc3c(s2)CCN(CC2CCCC2)c2n[nH]cc2-3)nc1,,O=C(O)C(F)(F)F,,,,test
US20070249612A1,CC(C)N.COC(=O)C(C)(C)c1cn2c(=O)n(C(C)(C)C)nc2c(Cl)n1>>COC(=O)C(C)(C)c1cn2c(=O)n(C(C)(C)C)nc2c(NC(C)C)n1,,C1CCOC1,O,,,test
US06924391B2,CC(Oc1ccc(C(=O)OC(C)(C)C)cc1)C(=O)COc1ccc(CCCO)cc1.CS(=O)(=O)Cl>>CC(Oc1ccc(C(=O)OC(C)(C)C)cc1)C(=O)COc1ccc(CCCOS(C)(=O)=O)cc1,,ClCCl,,CCN(CC)CC,,test
US20160115125A1,CC(C)(C)N.COC(=O)c1c(Cl)c(S(=O)(=O)Cl)cn1C>>COC(=O)c1c(Cl)c(S(=O)(=O)NC(C)(C)C)cn1C,,CC#N,,,,test
US20100099681A1,COC(=O)c1ccccc1Nc1cc(C)nn1-c1ccccc1C.COc1c(B2OC(C)(C)C(C)(C)O2)cc2nccnc2c1F>>COC(=O)c1ccccc1Nc1c(-c2cc3nccnc3c(F)c2OC)c(C)nn1-c1ccccc1,,C1COCCO1,,C1CCC(P(C2CCCCC2)C2CCCCC2)CC1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20090252687A1,CC(=O)C(C)CCCCCC(=O)O.NNc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC1=Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2C1(C)CCCCCC(=O)O,,CC(=O)O,,Cl,,test
US20140213786A1,CCOC(=O)C(Cc1ccnc(NC(C)=O)c1F)C(C)=O.CS(=O)(=O)O.Oc1cccc(O)c1>>CS(=O)(=O)O.Cc1c(Cc2ccnc(N)c2F)c(=O)oc2cc(O)ccc12,,CCO,CCOC(C)=O,O,,test
US20100130446A1,CON(C)C(=O)Cc1ccc(C(=O)OC(C)(C)C)cc1.ICC1CCOCC1>>CON(C)C(=O)C(CC1CCOCC1)c1ccc(C(=O)OC(C)(C)C)cc1,,C1CCOC1,CN1CCCN(C)C1=O,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US05968982,CCO.O=C(O)C(Cl)(Cl)CCCCCCCCCCCCBr>>CCOC(=O)C(Cl)(Cl)CCCCCCCCCCCCBr,CN(C)C=O,ClCCl,O,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20070219186A1,CN1CCNCC1.O=C(Nc1cccc(-c2ccnc3c(-c4ccnc(Cl)c4)cnn23)c1)c1cccc(C(F)(F)F)c1>>CN1CCN(c2cc(-c3cnn4c(-c5cccc(NC(=O)c6cccc(C(F)(F)F)c6)c5)ccnc34)ccn2)CC1,,CN1CCCC1=O,,,,test
US20090274632A1,CS(=O)(=O)c1csc(C(=O)Cl)c1Cl.Cc1noc(C)c1Cn1cc(N)cn1>>Cc1noc(C)c1Cn1cc(NC(=O)c2scc(S(C)(=O)=O)c2Cl)cn1,,CC#N,ClCCl,CCN(CC)CC,Cl,test
US20090312370A1,CI.O=C(O)c1cc(Cl)nc(CO)c1>>COCc1cc(C(=O)O)cc(Cl)n1,,CN(C)C=O,,[H-].[Na+],,test
US20140228386A1,O=C1N(c2cc(Cl)nc(Cl)c2)CCN1c1cnccc1C1CC1.OB(O)C1CC1>>O=C1N(c2cc(Cl)nc(C3CC3)c2)CCN1c1cnccc1C1CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20040072829A1,BrB(Br)Br.CNCCc1ccc(OC)cc1>>Br.CNCCc1ccc(O)cc1,,ClCCl,,,,test
US04699928,CCOC(=O)C(C)(C(=O)OC(C)(C)C)C(F)F>>CCOC(=O)/C(C)=C/F,,O=C(O)C(F)(F)F,,,,test
US04798893,CC(=O)Cc1cc(OC(C)=O)ccc1C#Cc1ccccc1>>CC(=O)Cc1cc(O)ccc1C#Cc1ccccc1,,CO,,Cl,[Na+].[OH-],test
US20020133007A1,Cc1c(Cl)cc(F)c(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c1N.O=C(Cl)c1ccc2ccccc2c1>>Cc1c(Cl)cc(F)c(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c1NC(=O)c1ccc2ccccc2c1,,C1COCCO1,,CCN(CC)CC,,test
US20040259912A1,CCC(=O)c1cc(N)ccc1OCc1ccc(CC)cc1.COc1ccc(N=C=O)cc1OC>>CCC(=O)c1cc(NC(=O)Nc2ccc(OC)c(OC)c2)ccc1OCc1ccc(CC)cc1,,C1CCOC1,,,,test
US20060052348A1,COC(=O)CBr.Cn1cc(-c2ncc(-c3ccc4cc(O)ccc4c3)o2)c2ccccc21>>COC(=O)COc1ccc2cc(-c3cnc(-c4cn(C)c5ccccc45)o3)ccc2c1,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06207678B1,CS(=O)(=O)Cl.OCC(CCOC1CCCCO1)c1ccc(Cl)c(Cl)c1>>CS(=O)(=O)OCC(CCOC1CCCCO1)c1ccc(Cl)c(Cl)c1,,ClCCl,,CCN(CC)CC,,test
US20070078184A1,Cc1cc(Br)cc(C)c1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1cc(Br)cc(C)c1OS(=O)(=O)C(F)(F)F,,CCOC(C)=O,ClCCl,Cl,c1ccncc1,test
US20080249110A1,CCOC(=O)CBr.Cc1cc2cc([N+](=O)[O-])ccc2[nH]1>>CCOC(=O)Cn1c(C)cc2cc([N+](=O)[O-])ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20150080549A1,CC(C)(OC(=N)C(Cl)(Cl)Cl)c1ccc(C(F)(F)F)cc1.O=C(N[C@@H](CO)C(=O)O)OCC1c2ccccc2-c2ccccc21>>CC(C)(OC(=O)[C@H](CO)NC(=O)OCC1c2ccccc2-c2ccccc21)c1ccc(C(F)(F)F)cc1,,C1CCOC1,,,,test
US20150094328A1,Cc1cc(CBr)ccn1.O=C(N[C@H]1CCCC[C@@H]1O)c1c[nH]c2c(Cl)ccnc12>>Cc1cc(Cn2cc(C(=O)N[C@H]3CCCC[C@@H]3O)c3nccc(Cl)c32)ccn1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050059650A1,CNC.CS(=O)(=O)c1ccc(-n2ncc3c(O)ncnc32)c(F)c1>>CN(C)c1cc(S(C)(=O)=O)ccc1-n1ncc2c(O)ncnc21,,CS(C)=O,,,,test
US04125732,COC(=O)C(Br)c1ccc(OCC(C)Oc2ccc(C(F)(F)F)cc2)cc1.Oc1cccc(C(F)(F)F)c1>>COC(=O)C(Oc1cccc(C(F)(F)F)c1)c1ccc(OCC(C)Oc2ccc(C(F)(F)F)cc2)cc1,,C1CCOC1,,,,test
US20150080393A1,CS(=O)(=O)c1ccc(C(O)C(F)(F)F)c(-c2ccccc2)c1>>CS(=O)(=O)c1ccc(C(=O)C(F)(F)F)c(-c2ccccc2)c1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20150232469A1,CC(C)Nc1nc2cc(Br)ncc2nc1Cl.Fc1ccc(OC2CCNCC2)c(F)c1>>CC(C)Nc1nc2cc(Br)ncc2nc1N1CCC(Oc2ccc(F)cc2F)CC1,,C1COCCO1,,CCN(C(C)C)C(C)C,Cl,test
US20100267699A1,CC(C)(C)OC(=O)N1CCN(C2=Nn3c(nnc3C(F)(F)F)CC2)CC1>>FC(F)(F)c1nnc2n1N=C(N1CCNCC1)CC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040077669A1,CC#CCOc1cc(Cl)ncn1.NCC(F)(F)F>>CC#CCOc1cc(NCC(F)(F)F)ncn1,,CCOC(C)=O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20150266867A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc(CN2C(=O)[C@@H](NC(=O)OCc3ccccc3)[C@H]2CN2C(=O)CNC2=O)c(OC)c1>>COc1ccc(CN2C(=O)[C@@H](NC(=O)OCc3ccccc3)[C@H]2CN2C(=O)CN(C(=O)OC(C)(C)C)C2=O)c(OC)c1,CN(C)c1ccncc1,ClCCl,,O,,test
US20100048502A1,COCc1ccc2ccc(C=O)nc2c1Cl>>COCc1ccc2ccc(CO)nc2c1Cl,,CCO,,[BH4-].[Na+],,test
US06008230,CC(=O)O.Cc1cnc2c(NC(=O)c3c(Cl)cccc3Cl)cccc2c1Cl>>Cc1c[nH]c2c(NC(=O)c3c(Cl)cccc3Cl)cccc2c1=O,,CC(=O)O,Cl,CCO,,test
US20160137653A1,CC1(CNC(=O)c2ccc(Cl)cc2)CCN(C(=O)OC(C)(C)C)CC1>>CC1(CNC(=O)c2ccc(Cl)cc2)CCNCC1,,C1COCCO1,,Cl,,test
US06627651B1,CCOc1ccc(COc2ccc3c(c2)C=C(C(=O)OC)CCC3)cc1>>CCOc1ccc(COc2ccc3c(c2)C=C(C(=O)O)CCC3)cc1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US05714487,OC[C@H]1C[C@H]2CN(c3ncc(F)cn3)CCN2C1.Oc1ccc(F)cc1>>Fc1ccc(OC[C@H]2C[C@H]3CN(c4ncc(F)cn4)CCN3C2)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US07407968B2,CCN(CC)CC.CCO.O=C(c1ccc(F)c([N+](=O)[O-])c1)N(CC(F)(F)F)CC(F)(F)F>>O=C(c1ccc(NCC2CCCCO2)c([N+](=O)[O-])c1)N(CC(F)(F)F)CC(F)(F)F,,CCO,,,,test
US20100305104A1,CC1CCCCN1.COC(=O)c1ccc(F)c(C#N)c1>>CC1CCCCN1c1ccc(C(=O)O)cc1C#N,,CN(C)C=O,O,[Li+].[OH-],,test
US20080194576A1,O=C(Cl)c1ccccc1.O=C(OCc1ccccc1)N1CCNCC1>>O=C(OCc1ccccc1)N1CCN(C(=O)c2ccccc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20100160322A1,COC(=O)c1ccc(N2CCN(CC3=C(c4ccc(Cl)cc4)CCC4(CCN(C(=O)OCc5ccccc5)CC4)C3)CC2)cc1Oc1cnc(N)c(Cl)c1>>COC(=O)c1ccc(N2CCN(CC3=C(c4ccc(Cl)cc4)CCC4(CCNCC4)C3)CC2)cc1Oc1cnc(N)c(Cl)c1,[Pd],CCO,,,,test
US20100204196A1,COc1cc(C)c(NC(=O)CN(C)C)cc1[N+](=O)[O-]>>COc1cc(C)c(NC(=O)CN(C)C)cc1N,[Pd],CO,,,,test
US20080300288A1,COS(=O)(=O)OC.Cc1cc(Br)cc(C(=O)O)c1O>>COC(=O)c1cc(Br)cc(C)c1OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080045541A1,CC(=O)C(=Cc1ccc(C#N)cc1)C(C)=O.O=C(CC(=O)OCc1ccccc1)Nc1cccc(C(F)(F)F)c1>>CC(=O)C(C(C)=O)C(c1ccc(C#N)cc1)C(C(=O)Nc1cccc(C(F)(F)F)c1)C(=O)OCc1ccccc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05068393,CC1(C)CCC(C)(C)c2cc(C(=O)CCC(=O)O)ccc21.NCCOCCO>>CC1(C)CCC(C)(C)c2cc(C(=O)CCC(=O)NCCOCCO)ccc21,,ClCCl,,,,test
US05723619,CN(C)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)OC(C)(C)C.OO>>CN(C)NCCCC[C@@H](C(=O)OC(C)(C)C)[NH+]([O-])C(=O)OCc1ccccc1,,CO,,,,test
US20110172187A1,CCCS(=O)(=O)Cc1cc(NC(=O)C(F)(F)F)ccc1S(=O)(=O)Cl.Nc1ccc2c(c1)B(O)OC2>>CCCS(=O)(=O)Cc1cc(N)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2,,CC#N,,c1ccncc1,,test
US20140343092A1,COCCBr.Cc1c(-c2c(C(OC(C)(C)C)C(=O)O)n(C)c(=O)c3[nH]ccc23)ccc2c1CCCO2>>COCCn1ccc2c(-c3ccc4c(c3C)CCCO4)c(C(OC(C)(C)C)C(=O)O)n(C)c(=O)c21,,CC#N,O,,,test
US20110263584A1,Brc1cncs1.C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O>>C[C@@H](c1ccc(-c2cncs2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20130178460A1,CCc1cc([N+](=O)[O-])cc2cccnc12>>CCc1cc(N)cc2cccnc12,[Pd],CCO,,,,test
US20100234364A1,Nc1cc(Cl)ccc1C(=O)N1CCCCC1.O=S(=O)(Cl)c1ccc(Cl)c(C(F)(F)F)c1>>O=C(c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1)N1CCCC1,,CCOC(C)=O,c1ccncc1,,,test
US20080139600A1,Brc1cnc2c(c1)C[C@@]1(CN3CCC1CC3)O2.O=Cc1ccc(B(O)O)o1>>O=Cc1ccc(-c2cnc3c(c2)C[C@@]2(CN4CCC2CC4)O3)o1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],test
US20020019388A1,CC(N)c1ccccc1.CCOC(=O)CBr>>CCOC(=O)CN[C@H](C)c1ccccc1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20090105253A1,BrCCCc1ccccc1.CCNC(=O)c1ccc(-n2nnc(C(=O)OC)c2O)cc1>>CCNC(=O)c1ccc(-n2nnc(C(=O)OC)c2OCCCc2ccccc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120040985A1,BrC(Br)(Br)Br.CN(C)C=NS(=O)(=O)c1cc(F)c(CO)c(Cl)c1>>CN(C)C=NS(=O)(=O)c1cc(F)c(CBr)c(Cl)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100093757A1,CCOC=C(C#N)C#N.Cc1cnccc1NN>>Cc1cnccc1-n1ncc(C#N)c1N,,CO,,,,test
US04623662,CCCCNCc1ccccc1.O=C(Nc1cccc(Cl)c1)Oc1ccccc1>>CCCCN(Cc1ccccc1)C(=O)Nc1cccc(Cl)c1,,C1CCOC1,CCCCCC,,,test
US05693720,BrCc1ccc(-c2ccccc2)cc1.OCCS>>SCc1ccc(-c2ccccc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20160016968A1,CC(C)(C)c1nc(-c2cc(OCc3ccc(F)cc3)c(C3CC3)cn2)no1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)c1nc(-c2cc(OCc3ccc(F)cc3)c(C3CC3)c[n+]2[O-])no1,,ClCCl,,,,test
US20160207926A1,CC(C)(C)OC(=O)N1CC[C@H](N)C1.CCn1c(C(F)F)nc2c(Cl)ncnc21>>CCn1c(C(F)F)nc2c(N[C@H]3CCN(C(=O)OC(C)(C)C)C3)ncnc21,,CC(C)(C)O,,CCN(C(C)C)C(C)C,,test
US20070185155A1,BrCCCBr.Cc1ccccc1O>>Cc1ccccc1OCCCBr,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050176706A1,Cc1cc(C#N)cc([N+](=O)[O-])c1C#CCC(O)(CC(C)(C)c1cc(S(C)(=O)=O)cc2c1OCC2)C(F)(F)F>>Cc1cc(C#N)cc(N)c1C#CCC(O)(CC(C)(C)c1cc(S(C)(=O)=O)cc2c1OCC2)C(F)(F)F,[Fe],CCO,ClCCl,CC(=O)O,,test
US20090156572A1,CC(=O)N1CCC(C(=O)N2CC[C@@H](N(C)C(=O)C(F)(F)F)[C@H](c3ccc(Cl)c(Cl)c3)C2)CC1>>CN[C@@H]1CCN(C(=O)C2CCN(C(C)=O)CC2)C[C@H]1c1ccc(Cl)c(Cl)c1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20150175625A1,C=CCC1CCCC1O.CC(=O)Cl>>C=CCC1CC1OC(C)=O,,CC1CCCO1,,CCN(CC)CC,O,test
US20150344466A1,CCOC(=O)c1cc(Cc2ccc(OC(F)(F)F)cc2)on1>>O=C(O)c1cc(Cc2ccc(OC(F)(F)F)cc2)on1,,O,,CCO,[Na+].[OH-],test
US20060063769A1,CI.COc1ccccc1CCN(CCCCC(=O)c1ccc2c(c1)CCN2)C(=O)OC(C)(C)C>>COc1ccccc1CCN(CCCCC(=O)c1ccc2c(c1)CCN2C)C(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130005709A1,COc1ccc(S(=O)(=O)c2cc(Br)ccc2OC)cc1NC(=O)C(F)(F)F>>COc1ccc(S(=O)(=O)c2cc(Br)ccc2OC)cc1N,,CO,,[Na+].[OH-],,test
US05808062,O=CC1CCCCC1.O=c1oc(-c2ccccc2)cc(O)c1SSc1c(O)cc(-c2ccccc2)oc1=O.Sc1ccccc1>>O=c1oc(-c2ccccc2)cc(O)c1C(Sc1ccccc1)C1CCCCC1,,CC(=O)O,CCO,C1CCNCC1,,test
US20150232443A1,CCOC(=O)C1CCN(C2CC3CCC(C2)N3C(=O)OCC)CC1>>CCOC(=O)N1C2CCC1CC(N1CCC(C(=O)O)CC1)C2,,C1CCOC1,,Cl,[Li+].[OH-],test
US04258187,CCN1C(=O)Nc2ccc(Cl)cc2C1(O)c1ccccc1.NO>>O=c1[nH]c2ccc(Cl)cc2c(-c2ccccc2)[n+]1[O-],,CCO,,Cl,,test
US20050277652A1,CNC1CCN(C)CC1.O=C(Nc1cc(Oc2ccc([N+](=O)[O-])cc2)ccn1)Oc1ccccc1>>CN1CCC(N(C)C(=O)Nc2cc(Oc3ccc([N+](=O)[O-])cc3)ccn2)CC1,,CN(C)C=O,,,,test
US20120083513A1,N#Cc1ccc(/C=C/c2nc[nH]c2[N+](=O)[O-])cc1>>N#Cc1ccc(/C=C/c2nc[nH]c2N)cc1,[Pd],CO,,,,test
US20120283238A1,CC1(C)CCc2sc3ncnc(N[C@@H]4CC[C@@H](NC(=O)OC(C)(C)C)CC4)c3c2C1>>CN[C@@H]1CC[C@@H](Nc2ncnc3sc4c(c23)CC(C)(C)CC4)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120202785A1,CC(C)(C)OC(=O)N[C@@H](COCc1ccccc1)C(=O)O.N>>CC(C)(C)OC(=O)N[C@@H](COCc1ccccc1)C(N)=O,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20110021534A1,CCOC(=O)[C@H](Cc1ccc(O)cc1)OCC.Cc1ccccc1>>CCO[C@@H](Cc1ccc(O)cc1)C(=O)OCc1ccccc1,,Cc1ccccc1,,[H-].[Na+],,test
US20070110816A1,C1CCCCC1.CCCCCCCCCc1ccc(OCCOCCOCCOCCOCCO)cc1>>C1CCCCC1.CCCCCCCCCc1ccc(OCCOCCOCCOCCOCCO)cc1,,C1CCCCC1,,,,test
US20120225854A1,CC(=O)Cl.CC(C)NC[C@H]1CN(S(=O)(=O)c2cccs2)CCN1c1ccc(C(C)(O)C(F)(F)F)cc1>>CC(=O)N(C[C@H]1CN(S(=O)(=O)c2cccs2)CCN1c1ccc(C(C)(O)C(F)(F)F)cc1)C(C)C,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150246902A1,COc1ccc(N)cc1.O=[N+]([O-])c1ccc(Br)cc1F>>COc1ccc(Nc2cc(Br)ccc2[N+](=O)[O-])cc1,,C1CCOC1,,[H-].[Na+],,test
US05574044,CCOC(=O)N1CCC(N[C@@H]2CC[C@@H](n3c(=O)[nH]c4ccccc43)CC2)CC1>>O=c1[nH]c2ccccc2n1[C@@H]1CC[C@@H](NC2CCNCC2)CC1,,Cl,,[Na+].[OH-],,test
US20140187553A1,CC(C)Nc1cncc(Cl)n1.CCCC[SnH](CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)c1cncc(NC(C)C)n1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US06166006,COC(=O)C1=Cc2cc(-c3ccc(F)cc3)ccc2OCC1>>O=C(O)C1=Cc2cc(-c3ccc(F)cc3)ccc2OCC1,,CCO,,C1CCOC1,[Na+].[OH-],test
US20150158865A1,CSc1nnc(C(N)=O)c(Nc2ccc(C(=O)N3CCOCC3)cc2)n1.O=C(OO)c1cccc(Cl)c1.c1ccc2c(O[C@@H]3CCCNC3)nccc2c1>>Cl.NC(=O)c1nnc(N2CCC[C@@H](Oc3nccc4ccccc34)C2)nc1Nc1ccc(C(=O)N2CCOCC2)cc1,,CCOC(C)=O,CN1CCCC1=O,CCN(C(C)C)C(C)C,,test
US20070179164A1,CCOC(=O)c1cncnc1NC(C)=O.Nc1ccccc1>>Nc1ncncc1C(=O)Nc1ccccc1,,ClCCl,,C[Al](C)C,,test
US04028376,BrBr.CN(C)C(=O)Nc1cc(C(C)(C)C)no1>>CN(C)C(=O)Nc1onc(C(C)(C)C)c1Br,,ClCCl,,CC(=O)O,CC(=O)[O-].[Na+],test
US20160145247A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCC[C@@H](N)c1cccc(Br)c1F>>CCC[C@@H](NC(=O)OC(C)(C)C)c1cccc(Br)c1F,,CO,,CCN(CC)CC,Cl,test
US20080280925A1,COc1ccccc1CNC(=O)c1cc(C(F)(F)F)nn1-c1cccc(CN)c1.C[C@@H](NC(=O)OC(C)(C)C)C(=S)n1c(=O)[nH]c2ccc(F)cc21>>COc1ccccc1CNC(=O)c1cc(C(F)(F)F)nn1-c1cccc(CNC(=S)[C@H](C)NC(=O)OC(C)(C)C)c1,,CN(C)C=O,O,,,test
US20030114666A1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.NC1CCc2sccc21>>c1ccc(C(NC2CCc3sccc32)(c2ccccc2)c2ccccc2)cc1,,ClCCl,,CCN(CC)CC,,test
US20010039344A1,COc1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1F>>O=C(Nc1nccs1)C(CC1CCCC1)c1ccc(O)c(F)c1,,ClCCl,,BrB(Br)Br,,test
US20080009619A1,CC(=O)Oc1ccc(Cl)cc1/C=C/c1ccccc1Br.COCN(C)[Si](C)(C)C>>CN1CC[C@@H](c2cc(Cl)ccc2O)[C@@H]1c1ccccc1Br,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US20150353553A1,CC(=O)NNC(=O)[C@@H]1COCCN1C(=O)OC(C)(C)C>>Cc1nnc([C@@H]2COCCN2C(=O)OC(C)(C)C)o1,,ClCCl,O,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US04592857,CCCc1ccc(C(=O)C=O)cc1.N#C/C(N)=C(/N)C#N>>CCCc1ccc(-c2cnc(C#N)c(C#N)n2)cc1,Cc1ccc(S(=O)(=O)O)cc1,c1ccccc1,,O,,test
US05464840,CN1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1>>CN1CCC(=C2c3ccccc3CCc3ccccc32)CC1,O=[Pt],CC(=O)O,CCO,[H][H],,test
US20090209522A1,CC(C)(C)OCCO.COc1nc(Cl)nc(OC)c1[N+](=O)[O-]>>COc1nc(OCCOC(C)(C)C)nc(OC)c1[N+](=O)[O-],,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US20070032494A1,CCOC(=O)NC(=O)C(C#N)=NNc1cc(Cl)c(Cc2cc(C(C)C)c(=O)n(C)n2)c(Cl)c1>>CC(C)c1cc(Cc2c(Cl)cc(-n3nc(C#N)c(=O)[nH]c3=O)cc2Cl)nn(C)c1=O,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20040082630A1,COC(=O)CNS(=O)(=O)c1ccc(OCC2CC2)cc1.ClCc1ccc(-n2nccn2)cc1>>COC(=O)CN(Cc1ccc(-n2nccn2)cc1)S(=O)(=O)c1ccc(OCC2CC2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04664694,C=O.Nc1ccc(Cl)c(Cl)c1.O=C(O)CC(S)C(=O)O>>O=C(O)CC1SCN(c2ccc(Cl)c(Cl)c2)C1=O,,Cc1ccccc1C,,O,,test
US20080275037A1,Cc1ncc([C@H](N)CO[Si](C)(C)C(C)(C)C)cn1.N#Cc1cc(Cl)ccc1N1CCc2ncnc(Cl)c2C1>>Cc1ncc([C@@H](CO[Si](C)(C)C(C)(C)C)Nc2ncnc3c2CN(c2ccc(Cl)cc2C#N)CC3)cn1,,CC#N,,CCN(C(C)C)C(C)C,,test
US04182881,ClP(Cl)(Cl)(Cl)Cl.NC(=O)c1cccc(Oc2ccccc2)c1.O=CO>>O=C(NP(=O)(Cl)Cl)c1cccc(Oc2ccccc2)c1,,ClC(Cl)(Cl)Cl,,,,test
US20130029846A1,CCNC.Cc1cc2cc(N)ccc2[nH]1.ClCCl>>CCN(C)C=Nc1ccc2[nH]c(C)cc2c1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05629295,CC(=O)O[C@@H]1[C@H](O[Si](C)(C)C)[C@H]2[C@@H](CC[C@H]3C[C@@H](O[Si](C)(C)C(C)(C)C)CC[C@@]32C)[C@@H]2C[C@@H]3O[C@]4(CC[C@@H](C)CO4)[C@@H](C)[C@@H]3[C@]21C>>C[C@@H]1CC[C@@]2(OC1)O[C@H]1C[C@H]3[C@@H]4CC[C@H]5C[C@@H](O[Si](C)(C)C(C)(C)C)CC[C@]5(C)[C@H]4[C@@H](O[Si](C)(C)C)[C@@H](O)[C@]3(C)[C@H]1[C@@H]2C,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],[Cl-].[NH4+],test
US20150315126A1,CN1CCN(c2ccc(C(=O)OC(C)(C)C)cc2N)CC1.O=C(Cl)OCc1ccccc1>>CN1CCN(c2ccc(C(=O)OC(C)(C)C)cc2NC(=O)OCc2ccccc2)CC1,,C1CCOC1,,,,test
US20130045994A1,CO.COC(=O)c1cccc(OCc2nc3ccc(Oc4ncc(Br)c(Cl)c4Br)cc3n2C)c1>>COC(=O)c1cccc(OCc2nc3ccc(Oc4ncc(Br)c(OC)c4Br)cc3n2C)c1,,CO,,O,C[O-].[Na+],test
US20050054681A1,CC(=O)OC(C)=O.CNCCCOc1cc(=O)oc2ccc(Cl)cc12>>CC(=O)NCCCOc1cc(=O)oc2ccc(Cl)cc12,,ClCCl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20150005281A1,CC(=O)N1CCCC[C@@H]1CNc1nc(Nc2cnn(C)c2)ncc1Cl.CNC(=O)Cn1cc(N)cn1>>CNC(=O)Cn1cc(Nc2ncc(Cl)c(NC[C@H]3CCCN3)n2)cn1,,CC(C)O,,C1COCCO1,Cl,test
US06008245,CC1(C)Oc2ccc(OCc3ccccc3)cc2C(O)C1Br>>CC1(C)Oc2ccc(OCc3ccccc3)cc2C2OC21,,C1CCOC1,,[K+].[OH-],,test
US20050014812A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)CCCOc1cc(C)c(N)c([N+](=O)[O-])c1>>CCOC(=O)CCCOc1cc(C)c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c([N+](=O)[O-])c1,,CN(C)C=O,,[H-].[Na+],,test
US05985905,CCOC(=O)c1cc2cc(Cl)c(Cl)cc2[nH]1>>O=Cc1cc2cc(Cl)c(Cl)cc2[nH]1,O=[Mn]=O,C1CCOC1,ClCCl,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110142796A1,O=C(OCC1c2ccccc2-c2ccccc21)N1CCOC2(CCNCC2)C1>>CN1CCOC2(CCNCC2)C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140315902A1,CCO.COc1cc(OC)c(F)c(N2Cc3cnc(N)c(Br)c3N(C)C2=O)c1F>>CCOc1c(N)ncc2c1N(C)C(=O)N(c1c(F)c(OC)cc(OC)c1F)C2,[Cu],CO,,[K+].[OH-],,test
US20080015353A1,COC=CC(=O)C(C)(OC)OC.CONC(=N)O>>COc1nccc(C(C)(OC)OC)n1,,CCOC(C)=O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20100099695A1,C=CCCC[C@@H]1CCC[C@H]1O.C=COC(C)=O>>C=CCCC[C@@H]1CCC[C@H]1OC(C)=O,,CCOCC,,,,test
US20020040020A1,C[Si](C)(C)N=C=O.N#Cc1ccccc1N1CCN(CC(O)Cn2nc(-c3ccc(I)cc3)c3c2CCNC3)CC1>>N#Cc1ccccc1N1CCN(CC(O)Cn2nc(-c3ccc(I)cc3)c3c2CCN(C(N)=O)C3)CC1,CN(C)c1ccncc1,ClCCl,c1ccncc1,CCN(C(C)C)C(C)C,,test
US20080312226A1,Cc1nc2ccc(NC(=O)OCC(Cl)(Cl)Cl)cc2o1.c1ccc(-c2csc(N3CCNCC3)n2)cc1>>Cc1nc2ccc(NC(=O)N3CCN(c4nc(-c5ccccc5)cs4)CC3)cc2o1,,O,,CCN(C(C)C)C(C)C,CS(C)=O,test
US05436247,CCOC(=O)CC(=O)O.O=C(O)CCCn1ccnc1>>CCOC(=O)CC(=O)CCCn1ccnc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20090076070A1,N#Cc1cccc2[nH]ccc12.NC(=O)CBr>>N#Cc1cccc2c1ccn2CC(N)=O,,CN(C)C=O,,O,[H-].[Na+],test
US20160248021A1,COC(CC#N)(OC)OC.N#Cc1ccc(O)c(N)c1>>N#CCc1nc2cc(C#N)ccc2o1,,CC#N,,,,test
US20090227788A1,C=O.COC(=O)NCCSc1ccc(OC)cc1>>COC(=O)N(CO)CCSc1ccc(OC)cc1,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05374653,CC(=O)OC(C)=O.CCOC(C)O[C@@H]1OC=C(CO)[C@H]2CC[C@H](C)[C@H]21>>CCOC(C)O[C@@H]1OC=C(COC(C)=O)[C@H]2CC[C@H](C)[C@H]21,,ClCCl,,CCOC(C)=O,c1ccncc1,test
US20100256092A1,CC(C)(C)OC(=O)N1CCC(O)CC1.O=Cc1ccc(O)cc1O>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(C=O)c(O)c2)CC1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110184188A1,CSC[C@H](C)N=C1OC(=O)c2cccc(OC(F)(F)F)c21.Cc1ccc(S(=O)(=O)O)cc1.Nc1ccc(Cn2nc(C(F)(F)F)cc2C(F)(F)F)cc1>>CSC[C@H](C)NC(=O)c1c(OC(F)(F)F)cccc1C(=O)Nc1ccc(Cn2nc(C(F)(F)F)cc2C(F)(F)F)cc1C,,CC#N,,O,,test
US06180627B2,CC(C)(C)OC(=O)NCCO.N#CCc1cccc(O)c1>>CC(C)(C)OC(=O)NCCOc1ccccc1CC#N,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04439448,CCOC(=O)Cc1ccc(N[C@@H](CCC(N)=O)C(=O)O)cc1.Cl>>CCOC(=O)Cc1ccc(N[C@@H](CCC(N)=O)C(=O)O)cc1.Cl,,CCO,O,,,test
US05344845,CCOC(=O)COc1ccc(C=CC(=O)N[C@H]2CC[C@H](C)CC2)cc1OC>>COc1cccc(C=CC(N)=O)c1,,CO,,[K+].[OH-],,test
US20080234277A1,CCOC(=O)C(N=CN(C)C)C(=O)OCC.NN>>CCOC(=O)C1NC=NNC1=O,,CCO,,,,test
US20070249642A1,CCC(Cl)Br.O=C(c1ccccc1)n1c(=O)[nH]cc(I)c1=O>>O=C(c1ccccc1)n1c(=O)c(I)cn(CCCCl)c1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150225342A1,C=C(OCC)c1cnc(OCc2ccccc2)cn1.O=C1CCC(=O)N1Br>>O=C(CBr)c1cnc(OCc2ccccc2)cn1,,C1CCOC1,O,,,test
US04227014,ClC(Cl)Cl.O=C(Cl)OCc1ccccc1.O=C(O)c1ccc(NCCCCCCCCC2CCCCC2)cc1>>O=C(Cl)c1ccc(N(CCCCCCCCC2CCCCC2)C(=O)OCc2ccccc2)cc1,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US04409238,CC(C)C(C=C(Cl)Cl)C(=O)O.O=S(Cl)Cl>>CC(C)C(C=C(Cl)Cl)C(=O)Cl,,c1ccccc1,,,,test
US20120245136A1,CC(C)Br.Cc1cc(C(=O)N2CCC3(CC2)CC(O)c2cccnc2O3)ccc1OC(C)C>>Cc1cc(C(=O)N2CCC3(CC2)CC(OC(C)C)c2cccnc2O3)ccc1OC(C)C,CN(C)c1ccncc1,CO,,CN(C)C=O,[H-].[Na+],test
US20150094474A1,CNC(=O)c1cc(C#N)cc(C)c1N.O=Cc1cc(Br)nn1-c1ncccc1Cl>>CNC(=O)c1cc(C#N)cc(C)c1N=Cc1cc(Br)nn1-c1ncccc1Cl,,Cc1ccccc1,,,,test
US20060258691A1,CCOC(=O)c1cn(C(C)(C)C)c2nc(NC(=O)c3ccc(C)cc3)ccc12>>Cc1ccc(C(=O)Nc2ccc3c(C(=O)O)cn(C(C)(C)C)c3n2)cc1,,CCO,CCOC(C)=O,[Na+].[OH-],,test
US04859684,CCOC(=O)c1ccccc1Cl.Nc1ccc(Cn2ccnc2)cc1N>>Clc1ccccc1-c1nc2cc(Cn3ccnc3)ccc2[nH]1,,O,,[NH4+].[OH-],,test
US20140135332A1,CC(=O)OCCc1nc(-c2ccc(C(F)(F)F)cc2)c(Br)o1>>OCCc1nc(-c2ccc(C(F)(F)F)cc2)c(Br)o1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20160272633A1,Brc1ccc2c(c1)CNC2.CC(C)C=O>>CC(C)CN1Cc2ccc(Br)cc2C1,,CO,,Cl,[BH4-].[Na+],test
US05521196,CN(C)C1CCC2(CC1)OCCO2>>CN(C)C1CCC(=O)CC1,,O=CO,,,,test
US07618996B2,CC1(C)OC(=O)c2ccc(O)cc2O1.O=Cc1cc(F)c(F)c(F)c1>>CC1(C)OC(=O)c2ccc(Oc3c(F)cc(C=O)cc3F)cc2O1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040186160A1,CNC.O=C(O)CCc1c(/C=C2\C(=O)Nc3ccc(Br)cc32)[nH]c2c1CCCCC2>>CN(C)C(=O)CCc1c(/C=C2\C(=O)Nc3ccc(Br)cc32)[nH]c2c1CCCCC2,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US04740228,CCOC(=O)C(C#N)(CC)c1ccccc1.N>>CCC(C#N)(C(N)=O)c1ccccc1,,CCO,,,,test
US20160009744A1,CC(C)(C)OC(=O)NC(c1cc(C2OCCO2)sc1Cl)c1nc(Cl)ccc1CCO[Si](C)(C)C(C)(C)C>>CC(C)(C)OC(=O)NC(c1cc(C2OCCO2)sc1Cl)c1nc(Cl)ccc1CCO,,C1CCOC1,,,,test
US20100144825A1,CN(CC(=O)O)C(=O)OC(C)(C)C.N#CCCNc1cccc(Cl)c1>>CN(CC(=O)N(CCC#N)c1cccc(Cl)c1)C(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05932707,CC(=O)NCCNC(=O)CCSC(C)=O.ClCCSC1CCCCO1>>CC(=O)NCCNC(=O)CCSCCSC1CCCCO1,,O,,CO,[K+].[OH-],test
US20080108638A1,CC(C)(C)OC(=O)Cn1c(SCCC2CCCCC2)nc2ccccc21>>O=C(O)Cn1c(SCCC2CCCCC2)nc2ccccc21,,ClCCl,O=C(O)C(F)(F)F,,,test
US20150329538A1,CCOC(=O)CN.O=[N+]([O-])c1c(F)cccc1Br>>CCOC(=O)CNc1cccc(Br)c1[N+](=O)[O-],,CC(=O)N(C)C,ClCCl,CCN(C(C)C)C(C)C,Cl,test
US20070298104A1,CCOC(=O)c1cccc(Oc2ccc(F)cc2)c1CBr.COC(=O)CNS(=O)(=O)c1ccc(C)cc1>>CCOC(=O)c1cccc(Oc2ccc(F)cc2)c1CN(CC(=O)OC)S(=O)(=O)c1ccc(C)cc1,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20030195193A1,O=C(OCc1ccccc1)c1cccc(OCc2ccccc2)c1[N+](=O)[O-]>>O=C(O)c1cccc(OCc2ccccc2)c1[N+](=O)[O-],,CCO,,[Na+].[OH-],,test
US20130059843A1,CCOC(=O)c1sc(I)nc1-c1ccccc1>>O=C(O)c1sc(I)nc1-c1ccccc1,,CCO,,Cl,[Na+].[OH-],test
US20090198063A1,COc1cnc2ccc(=O)n(CCN3CCC(N(Cc4cc5c(cn4)OCCO5)C(=O)OC(C)(C)C)CC3)c2c1.Cl>>COc1cnc2ccc(=O)n(CCN3CCC(NCc4cc5c(cn4)OCCO5)CC3)c2c1.Cl,,CCOC(C)=O,,,,test
US06326369B1,COc1c2c(c(OC)c(OC)c1OC)CC(CCCCCCCCO)C2.CS(=O)(=O)Cl>>COc1c2c(c(OC)c(OC)c1OC)CC(CCCCCCCCOS(C)(=O)=O)C2,,CC#N,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20070105904A1,Fc1ccc(CBr)cc1.Nc1ncccc1-c1cc(Cc2ccc(O)cc2)no1>>Nc1ncccc1-c1cc(Cc2ccc(OCc3ccc(F)cc3)cc2)no1,,CO,,[Na+].[OH-],,test
US20160024082A1,Cc1nc(Cl)c2c(n1)CN(C(=O)OC(C)(C)C)CC2.OB(O)c1ccccc1>>Cc1nc2c(c(-c3ccccc3)n1)CCNC2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20090012084A1,CC(C)=O.CC(Cl)Cl.COc1cc2nnc(C#N)c(Nc3ccc(C)cc3F)c2cc1C1=CCNCC1>>COc1cc2nnc(C#N)c(Nc3ccc(C)cc3F)c2cc1C1=CCN(C(C)C)CC1,,CC(Cl)Cl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140206681A1,CCOC(=O)C1CCN(C(=O)OCc2ccccc2)C(C(N)=O)C1>>CCOC(=O)C1CCN(C(=O)OCc2ccccc2)C(C#N)C1,,c1ccncc1,,O=S(Cl)Cl,,test
US20120184542A1,CC(C)(C)OC(=O)NCC(N)c1ccccc1.COc1ncc2cc(C(=O)Nc3cc(C(=O)O)ccc3Cl)c(=O)[nH]c2n1>>COc1ncc2cc(C(=O)Nc3cc(C(=O)NC(CNC(=O)OC(C)(C)C)c4ccccc4)ccc3Cl)c(=O)[nH]c2n1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140038990A1,CN.COC(=O)c1nc(Cc2ccccc2-c2ccccc2)n(C)c(=O)c1O>>CNC(=O)c1nc(Cc2ccccc2-c2ccccc2)n(C)c(=O)c1O,,C1CCOC1,,,,test
US05719141,CN=C=O.Nc1cnc2ccccc2c1>>CNC(=O)Nc1cnc2ccccc2c1,,ClCCl,,,,test
US04574126,CN.CSC(=C[N+](=O)[O-])NCCSCc1cc(CN(C)C)ccn1>>CNC(=C[N+](=O)[O-])NCCSCc1cc(CN(C)C)ccn1,,CCO,,,,test
US20150284373A1,CC(C)(C)OC(=O)N1CCC(CO)CC1.Nc1cncnc1Cl>>CC(C)(C)OC(=O)N1CCC(COc2ncncc2N)CC1,,C1CCOC1,,[H-].[Na+],,test
US20050080074A1,C=CCc1cc2c(c(C(F)(F)F)c1)C(=O)N1CCN(C(=O)OC(C)(C)C)C[C@@H]21>>CCCc1cc2c(c(C(F)(F)F)c1)C(=O)N1CCN(C(=O)OC(C)(C)C)C[C@@H]21,[Pd],CO,,[H][H],,test
US05110815,CC1(O)CCCc2nc(OCc3ccccc3)ccc21.NOCc1ccccc1>>CC1(NOCc2ccccc2)CCCc2nc(OCc3ccccc3)ccc21,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US20160235734A1,CCOC(CCN)OCC.O=C(Cl)c1ccc(CCl)cc1>>CCOC(CCNC(=O)c1ccc(CCl)cc1)OCC,,ClCCl,,CCN(CC)CC,,test
US20100310512A1,CC(C)(C)OC(=O)N1C2CCC(C2)C1C(=O)O.NCC(=O)c1ccc(Br)cc1>>CC(C)(C)OC(=O)N1C2CCC(C2)C1C(=O)NCC(=O)c1ccc(Br)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020091163A1,COc1cc(O)ccc1O.COc1ccc(OC)c2cc3ccccc3cc12>>COC1=CC(=O)C2C3c4ccccc4C(c4c(OC)ccc(OC)c43)C2C1=O,,Cc1ccccc1,,,,test
US04665179,CC(O)CS(=O)(=O)c1cc([N+](=O)[O-])ccc1Cl.NCCN>>CC(O)CS(=O)(=O)c1cc([N+](=O)[O-])ccc1NCCN,,CC(C)O,O,,,test
US04186135,CCOS(=O)(=O)[O-].O=C(O)c1cc(S)cc2c1OCCO2>>CCSc1cc2c(c(C(=O)O)c1)OCCO2,,O,,,,test
US20140343093A1,CCOC(=O)c1cc(C)n(-c2ccc(Br)cc2C(=O)N2Cc3ccccc3C[C@H]2CO)n1>>Cc1cc(C(=O)O)nn1-c1ccc(Br)cc1C(=O)N1Cc2ccccc2C[C@H]1CO,,C1CCOC1,O,[Li+].[OH-],,test
US20060264429A1,Cc1ccc2c(N3CCN(CC(=O)c4ccc5c(c4)NC(=O)CO5)CC3)cc(Cl)cc2n1>>Cc1ccc2c(N3CCN(CC(O)c4ccc5c(c4)NC(=O)CO5)CC3)cc(Cl)cc2n1,,CO,ClCCl,[BH4-].[Na+],,test
US04785017,BrCCCCCBr.COC(=O)[C@]1(C)CCc2c(C)c(O)c(C)c(C)c2O1>>COC(=O)[C@]1(C)CCc2c(C)c(OCCCCCBr)c(C)c(C)c2O1,,ClC(Cl)Cl,,,,test
US20090143413A1,CC#N.CCN=C=NCCCN(C)C.COc1c(C(C)(C)C)cc(-c2nc(C3CCN(C(=O)Cn4c(=O)[nH]c5ccccc54)CC3)sc2Cl)cc1C(C)(C)C.[Br-]>>CC(C)(C)c1cc(-c2nc(C3CCN(C(=O)Cn4c(=O)[nH]c5ccccc54)CC3)sc2Br)nc(C(C)(C)C)n1,,CC#N,CN(C)C=O,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US04073795,COC(=O)C(=Cc1c[nH]c2cc(Cl)ccc12)[N+](=O)[O-].Cl>>COC(=O)C(N)=Cc1c[nH]c2cc(Cl)ccc12.Cl,,CCOCC,,CO,,test
US20140134133A1,COc1ncc(-c2ccc3nccn3c2)cc1NS(=O)(=O)C1CC1.O=C1CCC(=O)N1I>>COc1ncc(-c2ccc3ncc(I)n3c2)cc1NS(=O)(=O)C1CC1,,CC#N,,,,test
US20090247526A1,CCOC(=O)Cc1cc(NC(N)=S)ncc1Br.O=C(CBr)CCc1ccccc1>>CCOC(=O)Cc1cc(Nc2nc(CCc3ccccc3)cs2)ncc1Br,,CCO,,CCN(C(C)C)C(C)C,,test
US20110190489A1,Cn1ncc2cnc3[nH]c(-c4cccn4CC(=O)O)cc3c21.O=C(Cl)C(=O)Cl>>Cn1ncc2cnc3[nH]c(-c4cccn4CC(=O)Cl)cc3c21,,ClCCl,,CN(C)C=O,,test
US20040024066A1,Br.Cc1cc(C(=O)C=[N+]=[N-])nn1C(C)(C)C>>Cc1cc(C(=O)CBr)nn1C(C)(C)C,,CC(=O)O,,,,test
US20120122817A1,C1CCOC1.CCOC(=O)N=NC(=O)OCC.CCn1cc(C(=O)O)c(=O)c2cc(Br)cnc21>>CCn1cc(C(=O)OCCCO)c(=O)c2cc(Br)cnc21,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070010511A1,COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CCC3c3ccc(OCCN)cc3)cc21.O=C(O)c1cccc(F)c1>>COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CCC3c3ccc(OCCNC(=O)c4cccc(F)c4)cc3)cc21,CN(C)c1ccncc1,CN(C)C=O,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US20130296298A1,Fc1ccccc1-c1nnc2ccc(Cl)nn12.[SH-]>>Fc1ccccc1-c1nnc2ccc(S)nn12,,CCO,,O,,test
US20110207704A1,NC(=NO)c1ccc(N2CCC(F)(F)CC2)c(C(F)(F)F)c1.O=C(Cl)c1ccc(F)cc1>>Fc1ccc(-c2nc(-c3ccc(N4CCC(F)(F)CC4)c(C(F)(F)F)c3)no2)cc1,,Cc1ccccc1,,c1ccncc1,,test
US20160031899A1,CC(=O)OC[C@H]1C[C@@H](OC(C)=O)CC[C@]1(C)[C@H]1CC[C@@]2(C)[C@@H](CC[C@@]2(O)c2ccccn2)[C@@H]1CN>>C[C@]1([C@H]2CC[C@@]3(C)[C@@H](CC[C@@]3(O)c3ccccn3)[C@@H]2CN)CC[C@H](O)C[C@@H]1CO,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20100113462A1,CC1(C)OB(C2=CCCCC2)OC1(C)C.CCOC(=O)C1(NC(=O)c2cccc(C)c2I)Cc2ccccc2C1>>CCOC(=O)C1(NC(=O)c2cccc(C)c2C2=CCCCC2)Cc2ccccc2C1,[Pd],C1COCCO1,CCO,O=C([O-])[O-].[K+].[K+],,test
US20100137308A1,C=O.COc1ccc(C=C2CC(C)(C)NC(C)(C)C2)c([N+](=O)[O-])c1>>COc1ccc(C=C2CC(C)(C)N(C)C(C)(C)C2)c([N+](=O)[O-])c1,,CCOC(C)=O,CO,[BH3-]C#N.[Na+],,test
US05162322,CN1CC(CCCCCl)OC1=O.c1ccc(N2CCNCC2)cc1>>CN1CC(CCCCN2CCN(c3ccccc3)CC2)OC1=O,,CCCCO,,Cl,[I-].[K+],test
US20050197338A1,NC(=O)Nc1cn(-c2ccc(SC3CCCC3)cc2)nc1C(N)=O.OO>>NC(=O)Nc1cn(-c2ccc(S(=O)C3CCCC3)cc2)nc1C(N)=O,,O,,CC(=O)O,,test
US20080058340A1,O=S(=O)(Cl)C1CC1.O=c1[nH]c2c(F)cc(F)c(F)c2n1-c1ccc(I)cc1F>>O=c1n(-c2ccc(I)cc2F)c2c(F)c(F)cc(F)c2n1S(=O)(=O)C1CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20100130738A1,BrBr.COc1cccc2ccc(C(C)C)nc12>>COc1ccc(Br)c2ccc(C(C)C)nc12,,CO,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20120232054A1,Nc1ncnn2cc(C#CCN3CCCC3)cc12>>Nc1ncnn2cc(CCCN3CCCC3)cc12,[Pd],CO,,[H][H],,test
US06878712B1,CN(C)C(=O)c1ccc(C(=O)Cl)cc1.C[C@H]1CN[C@H](C)CN1C(=O)[C@@](C)(O)C(F)(F)F>>C[C@H]1CN(C(=O)c2ccc(C(=O)N(C)C)cc2)[C@H](C)CN1C(=O)[C@@](C)(O)C(F)(F)F,,CCOC(C)=O,,CCN(CC)CC,,test
US04563310,CCP(=O)(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].COC(=O)CBr>>CCP(=O)(OCC(=O)OC)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-],,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05030640,CC(C)(N)Cc1c[nH]c2ccccc12.c1cc2nnnn2cc1[C@@H]1CO1>>CC(C)(Cc1c[nH]c2ccccc12)NC[C@H](O)c1ccc2nnnn2c1,,CCO,,,,test
US20100308311A1,CCO.O=Cc1ccc(N(c2ccccc2)c2ccccc2)cc1>>O=C1CC(=O)c2cc3ccccc3cc21,,CCO,,,,test
US20090054465A1,COC(=O)/C=C/c1cnc(N[C@@H]2CCN(Cc3ccccc3N(C)C)C2)cn1>>CN(C)c1ccccc1CN1CC[C@@H](Nc2cnc(/C=C/C(=O)O)cn2)C1,,CO,,Cl,[Na+].[OH-],test
US20070275987A1,O=C(O)CCl.OCCc1cccc(F)c1>>O=C(O)COCCc1cccc(F)c1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20110105544A1,BrCc1ccccc1.COC(=O)CCCc1ccc(O)cc1>>COC(=O)CCCc1ccc(OCc2ccccc2)cc1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20020013464A1,CCOc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1C(N)=O>>CCOc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1C#N,,ClCCl,,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US20040082607A1,CC(C)Cn1c(CNC(=O)OC(C)(C)C)c(-c2ccccc2)c2cc(C(N)=O)ccc2c1=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)Cn1c(CNC(=O)OC(C)(C)C)c(-c2ccccc2)c2cc(C(N)=S)ccc2c1=O,,Cc1ccccc1,,,,test
US05494928,CC1CO1.Clc1ccc2[nH]ccc2c1>>CC(O)Cn1ccc2cc(Cl)ccc21,,C1CCOC1,CCOCC,O,[H-].[Na+],test
US20130130997A1,FC(F)COc1ccccc1.O=C(Cl)c1cc(Br)ccc1Cl>>O=C(c1ccc(OCC(F)F)cc1)c1cc(Br)ccc1Cl,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US05883106,Cc1nccn1-c1ccc(COc2cccc(C3(C#N)CCC3)c2)cc1.OO>>Cc1nccn1-c1ccc(COc2cccc(C3(C(N)=O)CCC3)c2)cc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090186831A1,CN.Cc1ccc(S(=O)(=O)O[C@@H]2CN(C(=O)OCc3ccccc3)[C@@H]3[C@@H](O)CO[C@H]23)cc1>>CN[C@H]1CN(C(=O)OCc2ccccc2)[C@@H]2[C@@H](O)CO[C@H]12,,CCO,,,,test
US04686232,CCOc1cc(N)cc2c1OCOC2.O=C(Cl)Cl.OCCF>>CCOc1cc(NC(=O)OCCF)cc2c1OCOC2,,Cc1ccccc1,,CCN(CC)CC,,test
US05614531,N#Cc1ccnc(N)c1.O=C(O)c1ccc(C(=O)CBr)cc1>>Br.N#Cc1ccn2cc(-c3ccc(C(=O)O)cc3)nc2c1,,CCO,,,,test
US20120184525A1,N#Cc1c(Cl)ccn2c(CC3CC3)nnc12.c1ccc(C2CCNCC2)cc1>>N#Cc1c(N2CCC(c3ccccc3)CC2)ccn2c(CC3CC3)nnc12,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040224939A1,CC(=O)NCC1CN(c2ccc3c(c2)CCCCC3=O)C(=O)O1>>CC(=O)NCC1CN(c2ccc3c(c2)CCCCC3O)C(=O)O1,,CCO,,[BH4-].[Na+],,test
US20100331312A1,COc1cccc(C(C)C[N+](=O)[O-])c1>>COc1cccc(C(C)CN)c1,[Pd],CO,,O=C[O-].[NH4+],,test
US04857645,CSC#N.O.c1ccc(Nc2ccccc2)cc1>>CSC(=O)c1ccccc1Nc1ccccc1,,Cc1ccccc1,,ClB(Cl)Cl,,test
US20090306057A1,Cl.N#Cc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)[C@@H]3[C@H]4CC[C@H](C4)[C@@H]3N(Cc3ccc(F)cc3)C1=O)N2>>Cl.NCc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)[C@@H]3[C@H]4CC[C@H](C4)[C@@H]3N(Cc3ccc(F)cc3)C1=O)N2,[Pd],CO,,,,test
US04751295,CC(C)(C)OC(=O)NCc1cccnc1.CON=C(C(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(C=CCI)CS[C@H]12)c1nsc(N)n1>>CON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=C(C=CC[n+]3cccc(CN)c3)CS[C@H]12)c1nsc(N)n1,,CS(C)=O,,CCOC(C)=O,,test
US20100069499A1,C#CCOc1c(C)cc(C(=O)O)cc1OC.O=S(Cl)Cl>>C#CCOc1c(C)cc(C(=O)Cl)cc1OC,,CN(C)C=O,,Cc1ccccc1,,test
US20150094297A1,CCN(CC)S(F)(F)F.COc1cc(OCc2nc(C3(O)CCOCC3)sc2C)c2cc(-c3cn4nc(OC)sc4n3)oc2c1>>COc1cc(OCc2nc(C3(F)CCOCC3)sc2C)c2cc(-c3cn4nc(OC)sc4n3)oc2c1,,ClCCl,,,,test
US07728152B2,COC(COC(=O)c1ccccc1)OC.Cc1ccc(S(=O)(=O)O)cc1>>O=C(OCC1OCCS1)c1ccccc1,,Cc1ccccc1,,O,,test
US20140256704A1,CCCS(=O)(=O)Cl.COc1c(F)cc(F)cc1-c1c[nH]c2ncc(-c3cnn(C4CCNCC4)c3)cc12>>CCCS(=O)(=O)N1CCC(n2cc(-c3cnc4[nH]cc(-c5cc(F)cc(F)c5OC)c4c3)cn2)CC1,,ClCCl,ClCCl,CCN(CC)CC,,test
US20130102776A1,COc1ccc2c(c1CN1CCN(C(=O)OC(C)(C)C)CC1)OCC2=O.Cc1ccc(S(=O)(=O)n2cc(C=O)c3ccccc32)cc1>>COc1ccc2c(c1CN1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1cn(S(=O)(=O)c3ccc(C)cc3)c3ccccc13)C2=O,,CO,,C1CCNCC1,,test
US20050214649A1,O=C1OCC(Sc2ccccc2)O1.O=S([O-])OO>>O=C1OCC(S(=O)(=O)c2ccccc2)O1,,CO,,O,,test
US06607867B1,C=C(C)C(=O)OC(C)(C)[Si](C)(C)C.CC(C)(C(=O)OC1CC2C=CC1C2)[Si](C)(C)C.O=C1C=CC(=O)O1>>C=C(C)C(=O)OC(C)(C)[Si](C)(C)C.CC(C)(C(=O)OC1=CC2CC1CC2C1=CC(=O)OC1=O)[Si](C)(C)C,,C1CCOC1,,,,test
US20160068512A1,CC(C)(C)OC(=O)N1CCC(Nc2nc(OCCO)nc3ccc(C(O)(c4ccc(Cl)cc4)c4ccc(Cl)cc4)cc23)CC1>>OCCOc1nc(NC2CCNCC2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2n1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20040224996A1,Cc1c(Cl)cccc1S(=O)(=O)Nc1nc(CCCNCCO)cs1.O=C(Cl)CCl>>Cc1c(Cl)cccc1S(=O)(=O)Nc1nc(CCCN2CCOCC2=O)cs1,,C1CCOC1,O,Cl,[K+].[OH-],test
US20120129840A1,CC(C)c1ccc(B(O)O)cc1.CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1Cl>>CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1-c1ccc(C(C)C)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,CCN(C(C)C)C(C)C,,test
US20140275096A1,CC[C@@H](COS(C)(=O)=O)NC(=O)OC(C)(C)C.[N-]=[N+]=[N-]>>CC[C@@H](CN=[N+]=[N-])NC(=O)OC(C)(C)C,,CN(C)C=O,,O,,test
US05981521,CCOC(=O)C=CC(CCC#N)(c1ccccc1)c1ccccc1>>CCOC(=O)CCC(CCC#N)(c1ccccc1)c1ccccc1,[Pd],CCO,,,,test
US04105663,CI.COc1ccc(CCNCC(O)c2ccc(C)s2)cc1OC>>COc1ccc(CCN(C)CC(O)c2ccc(C)s2)cc1OC,,c1ccccc1,,,,test
US20040058916A1,COC(=O)c1cc(C2CCN(C(=O)OCc3ccccc3)CC2)c(F)cc1SC>>CSc1cc(F)c(C2CCN(C(=O)OCc3ccccc3)CC2)cc1C(=O)O,,C1CCOC1,,O,[Li+].[OH-],test
US05405851,CCOC(=O)CC[C@H](NC(=O)c1ccc(S(=O)(=O)Nc2ccc3ccc4nc(N)[nH]c(=O)c4c3c2)cc1)C(=O)OCC>>Nc1nc2ccc3ccc(NS(=O)(=O)c4ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc4)cc3c2c(=O)[nH]1,,[Na+],[OH-],Cl,,test
US20070191309A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cc(C(=O)N2C[C@H](O)C[C@H]2CO)c(N)cc1OCc1ccccc1>>COc1cc(C(=O)N2C[C@H](O)C[C@H]2CO)c(NC(=O)OC(C)(C)C)cc1OCc1ccccc1,,C1CCOC1,,CCCCCC,CCOC(C)=O,test
US20060135763A1,COC(=O)c1ccc(NC2CC3CCC(C2)N3C)c(O)c1.O=[N+]([O-])c1ccccc1F>>COC(=O)c1ccc2c(c1)Oc1ccccc1N2C1CC2CCC(C1)N2C,,CN(C)C=O,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20120264749A1,COCC1CN(C(C)(C)C)CC2(CCN(C(=O)OC(C)(C)C)CC2)O1>>COCC1CN(C(C)(C)C)CC2(CCNCC2)O1,,ClCCl,,C1COCCO1,Cl,test
US20030187014A1,CCOC(=O)c1cnc2c(c(C)nn2-c2ccccn2)c1O.NCc1ccccc1>>Cc1nn(-c2ccccn2)c2ncc(C(=O)NCc3ccccc3)c(O)c12,,CCOC(C)=O,,,,test
US20040224958A1,CCC(Br)CC.O=c1ccc2cnc(Nc3ccccc3)nc2[nH]1>>CCC(CC)n1c(=O)ccc2cnc(Nc3ccccc3)nc21,,CN(C)C=O,,[H-].[Na+],,test
US03979444,COC(=O)C1CC(C#N)(c2ccc(OC)c(OC)c2)CCC1=O>>COc1ccc(C2(C#N)CCC(=O)CC2)cc1OC,,O,,CC(=O)O,O=S(=O)(O)O,test
US05763439,CC(C)(C)n1ncc([N+](=O)[O-])c(Cl)c1=O.CS>>CSc1c([N+](=O)[O-])cnn(C(C)(C)C)c1=O,,C1COCCO1,,[Na],,test
US20160221945A1,O=C(OCc1ccccc1)N1CCC(OC(F)(F)F)CC1>>FC(F)(F)OC1CCNCC1,[Pd],CO,,,,test
US20050288273A1,CC(=O)NC[C@H]1CN(c2cc(F)c3c(c2)CCCCC3=O)C(=O)O1.O=C(Cl)c1ccno1>>CC(=O)NC[C@H]1CN(c2cc(F)c3c(c2)CCCC(C(=O)c2ccno2)C3=O)C(=O)O1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04845219,CCCCCCCCCCCCCCCCCCOCC(CS(=O)(=O)CCN(C)C)OC.CI>>CCCCCCCCCCCCCCCCCCOCC(CS(=O)(=O)CC[N+](C)(C)C)OC.[I-],,CCOCC,,,,test
US20100239520A1,Cc1nc(Br)sc1C(=O)O.NCc1ccc(F)cc1>>Cc1nc(Br)sc1C(=O)NCc1ccc(F)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20100016371A1,C=CNc1cc(C)ccc1CCC(C)C.CCOC(=O)c1csc(Br)n1>>C=CN(c1nc(C(=O)OCC)cs1)c1cc(C)ccc1CCC(C)C,I[Cu]I,Cc1ccccc1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140275070A1,FC(F)(F)Cc1cc2c(N3CCNCC3)ncnc2s1.NS(=O)(=O)Cc1ccc(CC(=O)O)cc1>>NS(=O)(=O)Cc1ccc(CC(=O)N2CCN(c3ncnc4sc(CC(F)(F)F)cc34)CC2)cc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20130023671A1,CC(C)O.CC[Al+]CC.CC[Al].[C-]#N>>CC(C)O.CC[Al](C#N)CC,,C1CCOC1,,,,test
US20070173526A1,Nc1ccsc1C(=O)[O-]>>Nc1ccsc1C(=O)O,,CO,,Cl,[Na+].[OH-],test
US20020022638A1,CC(C)(C)[Si](Oc1ccc(OCc2ccccc2)cc1)(c1ccccc1)c1ccccc1.CCO>>CC(C)(C)[Si](Oc1ccc(OCC2CO2)cc1)(c1ccccc1)c1ccccc1,[Pd],,,C1=CCCCC1,,test
US20140288025A1,CCC=CCC=CCC=CCC=CCC=CCC=CCCC(=O)NCCN.CO.O=[N+]([O-])c1ccc(OP(=O)(Cl)Cl)cc1>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)NCCNP(=O)(OC)Oc1ccc([N+](=O)[O-])cc1,,ClCCl,,CCN(CC)CC,,test
US20100093730A1,CC(C)(C)OC(=O)NC1CCN(C(=O)CN2CCCC(c3ccccc3)(c3ccccc3)C2=O)CC1>>NC1CCN(C(=O)CN2CCCC(c3ccccc3)(c3ccccc3)C2=O)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US07071201B2,CC(=O)Cl.NCc1ccc(CCN2CCC(N3CCc4ccccc43)CC2)cc1>>CC(=O)NCc1ccc(CCN2CCC(N3CCc4ccccc43)CC2)cc1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20150197509A1,COC(=O)CN(CC1COC1)S(=O)(=O)c1ccc(F)cc1>>O=C(O)CN(CC1COC1)S(=O)(=O)c1ccc(F)cc1,,C1COCCO1,O,[K+].[OH-],,test
US20100305131A1,COC(=O)[C@H](O)C(Cc1ccc(-c2cccc(Cl)c2)cc1)NC(=O)OC(C)(C)C.Cl>>COC(=O)[C@H](O)C(N)Cc1ccc(-c2cccc(Cl)c2)cc1.Cl,,C1COCCO1,,,,test
US20040033988A1,CC(C)(C)[Si](C)(C)OC1CCC(CC(=O)O)CC1.NO>>CC(C)(C)[Si](C)(C)OC1CCC(CC(=O)NO)CC1,,CN(C)C=O,,On1nnc2ccccc21,,test
US20100016319A1,C1COCCN1.CCc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2Oc2ccnc(Cl)n2)cc1>>CCc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2Oc2ccnc(N3CCOCC3)n2)cc1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20070225332A1,CC(C)Oc1ccc(Oc2ccc(Br)cc2)nc1.O=CN1CCOCC1>>CC(C)Oc1ccc(Oc2ccc(C=O)cc2)nc1,,C1CCOC1,,[Li]CCCC,,test
US20110015157A1,CC(=O)OC(C)=O.C[C@@H](c1ccc(C2CCNCC2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O>>CC(=O)N1CCC(c2ccc([C@H](C)N3CC[C@](CC(C)(C)O)(c4ccccc4)OC3=O)cc2)CC1,CN(C)c1ccncc1,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20080171759A1,C=CCOC(=O)Cl.CCOC(=O)CNC(c1ccccc1)c1ccc(Cl)cc1>>C=CCOC(=O)N(CC(=O)OCC)C(c1ccccc1)c1ccc(Cl)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120178770A1,CC(C)(C)OC(=O)N1CCc2[nH]c(-c3ccnc(N)n3)c(-c3cccc(N)c3)c2C1=O.ClCCl.O=S(=O)(Cl)c1cccc(F)c1>>Cn1c2c(c(-c3cccc(NS(=O)(=O)c4cccc(F)c4)c3)c1-c1ccnc(N)n1)C(=O)N(C(=O)OC(C)(C)C)CC2,,ClCCl,,CCN(CC)CC,,test
US20110015240A1,CC(=O)Nc1nc(C(=O)O)cs1.CC(C)(C)OC(=O)NNC(=O)NCCc1ccc(O)cc1>>CC(=O)Nc1nc(C(=O)Oc2ccc(CCNC(=O)NNC(=O)OC(C)(C)C)cc2)cs1,,CCOC(C)=O,,O,O=C(n1ccnc1)n1ccnc1,test
US20040029290A1,O=C(O)CCc1ccc(O)c(C=Nc2ccccc2O)c1.O=C1CCC(=O)N1O>>O=C(CCc1ccc(O)c(C=Nc2ccccc2O)c1)ON1C(=O)CCC1=O,,C1COCCO1,,,,test
US20150057277A1,Nc1cccc(Oc2ccc3ncc(N4CCOCC4)nc3c2)c1.O=C=Nc1cccc(F)c1>>O=C(Nc1cccc(F)c1)Nc1cccc(Oc2ccc3ncc(N4CCOCC4)nc3c2)c1,,ClCCl,,,,test
US20050222408A1,COc1ccc(N2CCNCC2)cc1.O=C(Cl)c1ccc([N+](=O)[O-])o1>>COc1ccc(N2CCN(C(=O)c3ccc([N+](=O)[O-])o3)CC2)cc1,,CCN(CC)CC,ClCCl,,,test
US20160176875A1,CC(C)(C)OC(=O)N1CC2(CCNCC2)C1.O=C(O)C#Cc1ccc2c(c1)OCO2>>CC(C)(C)OC(=O)N1CC2(CCN(C(=O)C#Cc3ccc4c(c3)OCO4)CC2)C1,,CCOC(C)=O,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20100298336A1,CCn1nccc1CSc1nc(C)cc(O)n1.Cl>>CCn1nccc1CSc1nc(C)cc(O)n1.Cl,,CO,,C1COCCO1,,test
US20100173901A1,CC1(C)OB(c2cnn(CC3CC3)c2)OC1(C)C.CC1Cc2ccc(Br)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1>>CC1Cc2ccc(-c3cnn(CC4CC4)c3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,O,C1COCCO1,O=C([O-])O.[Na+],test
US20160152659A1,C#CCBr.CC(=O)O[C@H]1[C@H](C)O[C@@H](SC(N)=[NH2+])[C@H](OC(C)=O)[C@@H]1OC(C)=O>>C#CCS[C@@H]1O[C@@H](C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O,,Cc1ccccc1,,CC#N,CCN(CC)CC,test
US20110092517A1,CCOC(=O)COc1cc2onc(CCc3sc4cc(C(F)(F)F)ccc4c3C(C)C)c2cc1C>>Cc1cc2c(CCc3sc4cc(C(F)(F)F)ccc4c3C(C)C)noc2cc1OCC(=O)O,,CCO,,Cl,[Na+].[OH-],test
US20150258074A1,COc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(Cl)nc(C(C)=O)c12.C[Mg]Br>>COc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(Cl)nc(C(C)(C)O)c12,,C1CCOC1,,,,test
US04963563,CS(=O)(=O)Cl.Nc1ccc2c(c1)CCN(C(=O)CCc1ccccc1)C2>>CS(=O)(=O)Nc1ccc2c(c1)CCN(C(=O)CCc1ccccc1)C2,,c1ccncc1,,,,test
US06800648B2,CC=Cc1c(N)ccc2c1O[C@@H](COS(=O)(=O)c1ccc(C)cc1)CO2.COC(=O)Cl>>CC=Cc1c(NC(=O)OC)ccc2c1OC(COS(=O)(=O)c1ccc(C)cc1)CO2,,CCOC(C)=O,,CCN(C(C)C)C(C)C,,test
US20110257151A1,COC(=O)c1cc(F)ccc1N.O=Cc1cccc(Br)c1>>COC(=O)c1cc(F)ccc1N=Cc1cccc(Br)c1,,CCO,,,,test
US20110224188A1,C[C@H](NC(=O)c1cnc2n1[C@](C)(Cc1ccc(-c3ccc(F)cc3)cc1)C(=O)N2c1cc(Cl)cc(Cl)c1)C(=O)OC(C)(C)C>>C[C@H](NC(=O)c1cnc2n1[C@](C)(Cc1ccc(-c3ccc(F)cc3)cc1)C(=O)N2c1cc(Cl)cc(Cl)c1)C(=O)O,,ClCCl,O,O=C(O)C(F)(F)F,,test
US20130345120A1,C=CCOC(=O)N1CCC(C(=O)Nc2ncc(OC)cn2)N1C(=O)[C@H](CC1CCCC1)CN(C=O)OC1CCCCO1>>COc1cnc(NC(=O)[C@@H]2CCNN2C(=O)[C@H](CC2CCCC2)CN(C=O)OC2CCCCO2)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,ClCCl,,C1COCCN1,,test
US20110046133A1,Cc1cccc(C)c1C#C[Si](C)(C)C>>C#Cc1c(C)cccc1C,,C1CCOC1,CCCCCC,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090281072A1,CI.NC(=O)c1cnc(Nc2ccc(OC3CCNCC3)cc2)nc1NCc1c(F)ccc(F)c1F>>CN1CCC(Oc2ccc(Nc3ncc(C(N)=O)c(NCc4c(F)ccc(F)c4F)n3)cc2)CC1,,O,,CN1CCCC1=O,O=C([O-])[O-].[K+].[K+],test
US20160024056A1,CC1(C)CC(Cn2ccc3cc(-c4cnn(C5CCCCO5)c4)ccc32)CN1.O=S(=O)(Cl)c1ccccc1>>CC1(C)CC(Cn2ccc3cc(-c4cnn(C5CCCCO5)c4)ccc32)CN1S(=O)(=O)c1ccccc1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20060069077A1,CO[C@H]1O[C@H]2[C@@H](OC(=O)c3ccccc3)CO[C@H]2[C@@H]1OC>>CO[C@H]1O[C@H]2[C@H](O)CO[C@H]2[C@@H]1OC,,CCOC(C)=O,CO,[Na+].[OH-],,test
US04837238,C=CCNc1c(C(=O)OCC)cnc2cn[nH]c12.COC(C)(C)OC>>C=CCNc1c(C(=O)OCC)cnc2cn(C(C)(C)OC)nc12,Cc1ccc(S(=O)(=O)O)cc1,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150225367A1,CC(=O)NCCN.O=S(=O)(Cl)c1ccc(Br)cn1>>CC(=O)NCCNS(=O)(=O)c1ccc(Br)cn1,,ClCCl,,CCN(CC)CC,,test
US20140336185A1,COC(=O)CN(Cc1ccc(-c2noc(-c3ccc(-c4ccc(C)cc4)cc3)n2)cc1)C(=O)OC(C)(C)C>>COC(=O)CNCc1ccc(-c2noc(-c3ccc(-c4ccc(C)cc4)cc3)n2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080200540A1,CNOC.O=C(O)C1Cc2ccccc2O1>>CON(C)C(=O)C1Cc2ccccc2O1,,ClCCl,,Cl,O=C(n1ccnc1)n1ccnc1,test
US05089654,CC(=O)c1ccc(OCC=C(C)C)cc1OCC(=O)O.CCCCCCCc1ccc(C=O)cc1>>CCCCCCCc1ccc(C=CC(=O)c2ccc(OCC=C(C)C)cc2OCC(=O)O)cc1,,CCO,,[K+].[OH-],,test
US20070082912A1,CCOC(=O)c1cncc(N)c1.CCOC(C)=O.COc1ccc(COc2ccc(Br)cc2C(=O)CCC(C)=O)cc1.Cc1ccccc1>>CCCC(C)C.CCOC(=O)c1cncc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(OC)cc2)c1,,CCOC(C)=O,Cc1ccccc1,,,test
US04281008,CCCc1c(OCc2ccccc2)ccc2c(=O)cc(C=O)oc12.O=C(O)CC(=O)O>>CCCc1c(OCc2ccccc2)ccc2c(=O)cc(C=CC(=O)O)oc12,,c1ccncc1,,,,test
US20050009831A1,NC(=O)c1c(Cl)c(-c2ccccc2)n2c1CNCC2.O=S(=O)(Cl)Nc1ccccc1>>NC(=O)c1c(Cl)c(-c2ccccc2)n2c1CN(S(=O)(=O)Nc1ccccc1)CC2,,CC#N,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20040006056A1,CC(C)(C)OC(=O)CC1(c2ccc(NCn3nnc4ccccc43)cc2)CCCC1>>CNc1ccc(C2(CC(=O)OC(C)(C)C)CCCC2)cc1,,CCO,,[BH4-].[Na+],,test
US05106871,COCOc1ccc(C(=O)C=Cc2ccc(OCOC)c(OCOC)c2)c(OCOC)c1>>O=C(C=Cc1ccc(O)c(O)c1)c1ccc(O)cc1O,,CO,Cl,,,test
US05034394,NC1CCCCCCC1.Nc1nc(Cl)c2ncn([C@H]3C=C[C@@H](CO)C3)c2n1>>Nc1nc(NC2CCCCCCC2)c2ncn([C@H]3C=C[C@@H](CO)C3)c2n1,,CCO,,[Na+].[OH-],,test
US20110275586A1,O=C(Cl)c1ccccc1.O=C(NCC[C@H](O)C(=O)O)OCc1ccccc1>>O=C(NCC[C@H](OC(=O)c1ccccc1)C(=O)O)OCc1ccccc1,CN(C)c1ccncc1,C1CCOC1,,c1ccncc1,,test
US04456464,CCOP(C)(=O)C(C)Oc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]>>CC(Oc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-])P(C)(=O)O,,CCO,O,[K+].[OH-],,test
US20120088748A1,CCOC(=O)CBr.CCOC(=O)CN(CCO)C(=O)OC(C)(C)C>>CCOC(=O)COCCN(CC(=O)OCC)C(=O)OC(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20060046978A1,COC(=O)C(C)NC(=O)C(Cc1ccccc1)CP(=O)(O)C(C)NC(=O)CCC(NC(=O)OC(C)(C)C)C(=O)N1CCCC1C#N>>CC(NC(=O)C(Cc1ccccc1)CP(=O)(O)C(C)NC(=O)CCC(NC(=O)OC(C)(C)C)C(=O)N1CCCC1C#N)C(=O)O,,CCO,,[Na+].[OH-],,test
US20090270433A1,CS(=O)(=O)Cl.O=[N+]([O-])c1ccc(Br)c(CO)c1>>O=[N+]([O-])c1ccc(Br)c(CCl)c1,,CCOC(C)=O,O,C1CCOC1,CCN(C(C)C)C(C)C,test
US20120101039A1,CC(C(=O)O)c1ccc(Br)cc1F.CI>>COC(=O)C(C)c1ccc(Br)cc1F,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US06069156,CC(=O)O.CCC(Br)c1[nH]c2cc(C(=O)OC)ccc2c1C(=O)C(C)C>>CCC(OC(C)=O)c1[nH]c2cc(C(=O)OC)ccc2c1C(=O)C(C)C,,CC(=O)O,,CC(=O)[O-].[K+],,test
US20090298815A1,Cc1nccc(-c2sc(C3(C)CCN(C(=O)OC(C)(C)C)CC3)nc2-c2cccc(NS(=O)(=O)c3ccoc3)c2F)n1>>Cc1nccc(-c2sc(C3(C)CCNCC3)nc2-c2cccc(NS(=O)(=O)c3ccoc3)c2F)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130065861A1,CCCCCCCCCCNC(=O)OC[C@H](CSC[C@H](NC(=O)OCc1ccccc1)C(=O)OC(C)(C)C)OC(=O)NCCCCCCCCCC>>CCCCCCCCCCNC(=O)OC[C@H](CSC[C@H](NC(=O)OCc1ccccc1)C(=O)O)OC(=O)NCCCCCCCCCC,,ClCCl,O=C(O)C(F)(F)F,,,test
US05318966,COc1cccc2c1CC[C@H]1[C@@H]2CCN1CCC1CCCC1>>Oc1cccc2c1CC[C@H]1[C@@H]2CCN1CCC1CCCC1,,Br,,Cl,[Na+].[OH-],test
US20100160335A1,CC[Mg]Br.CCc1nc2c(C(=O)NCOC)cccn2n1>>CCC(=O)c1cccn2nc(CC)nc12,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20060122278A1,C1=CCC(c2ccccc2)(c2ccc(OCc3ccccc3)cc2)OC1>>Oc1ccc(C2(c3ccccc3)CCCCO2)cc1,[Pd],CCOC(C)=O,CO,,,test
US20070232583A1,CC(C)(C)OC(=O)NS(=O)(=O)Cl.Nc1cccc(-c2cccc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)(F)F)n3)c2)c1>>NS(=O)(=O)Nc1cccc(-c2cccc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)(F)F)n3)c2)c1,,ClCCl,,CCN(CC)CC,,test
US04806685,Cc1ccc(S(=O)(=O)O)cc1.NCCOc1ccc(/C(=C(\c2ccccc2)C(F)(F)F)c2ccccc2)cc1>>Cc1ccc(S(=O)(=O)O)cc1.NCCOc1ccc(/C(=C(\c2ccccc2)C(F)(F)F)c2ccccc2)cc1,,CC(C)O,,,,test
US20120232056A1,CI.COC(=O)c1ccc2nc(-c3ccc(F)cc3)c(NC(C)(C)C)nc2c1>>CN(c1nc2cc(C(=O)O)ccc2nc1-c1ccc(F)cc1)C(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20120004240A1,Cc1cc2ncc3cc(-c4ccccc4)c(-c4ccc(C5(NC(=O)OC(C)(C)C)CCC5)cc4)nc3n2n1>>Cc1cc2ncc3cc(-c4ccccc4)c(-c4ccc(C5(N)CCC5)cc4)nc3n2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06313153B1,CC(=O)OC(C)=O.O=C(/C=C/c1cccnc1)NCCc1cccc(O)c1>>CC(=O)Oc1cccc(CCNC(=O)/C=C/c2cccnc2)c1,,c1ccncc1,,CCOC(C)=O,,test
US05057537,CON=C(C(=O)OC)c1ccc2ccccc2c1O.Fc1ccccc1CCl>>CON=C(C(=O)OC)c1ccc2ccccc2c1OCc1ccccc1F,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20120046278A1,Nc1nc(N2CCNCC2)c2nc(CCc3ccc(F)cc3)sc2n1.O=C(Cl)COc1ccccc1>>Nc1nc(N2CCN(C(=O)COc3ccccc3)CC2)c2nc(CCc3ccc(F)cc3)sc2n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150299186A1,O=[N+]([O-])c1cccc(N2CCC2)c1>>Nc1cccc(N2CCC2)c1,[Pd],CCOC(C)=O,,,,test
US04824866,C1COCCN1.NS(=O)(=O)C(F)(F)F>>C1COCC[NH2+]1.NS(=O)(=O)C(F)(F)F,,CC(C)=O,,,,test
US20100087460A1,Cn1c(CI)nc(-c2ccncn2)cc1=O.O=C1NC(=O)c2ccccc21>>Cn1c(CN2C(=O)c3ccccc3C2=O)nc(-c2ccncn2)cc1=O,,CN(C)C=O,,O,[K],test
US06809097B1,COc1cc2nccc(Cl)c2cc1OC>>COc1cc2nccc(Cl)c2cc1OC,,CCOC(C)=O,,Cl,,test
US20150152108A1,CC(C)(C)OC(=O)N1CCCN(c2ccc3c(n2)N(C(=O)Nc2ccncn2)[C@H]2CCCN3C2)CC1>>O=C(Nc1ccncn1)N1c2nc(N3CCCNCC3)ccc2N2CCC[C@H]1C2,,CO,Cl,O,O=C([O-])[O-].[K+].[K+],test
US20160145270A1,Cc1cn2cc(NC(=O)c3ccc(C4=CCNCC4)nc3)cc(F)c2n1.Cl.Cl>>Cc1cn2cc(NC(=O)c3ccc(C4CCNCC4)nc3)cc(F)c2n1.Cl.Cl,[Pd],C1CCOC1,CO,,,test
US20080194585A1,CC(C)Cn1c(-c2c(F)cccc2F)c(Cl)nc(Cl)c1=O.Cn1cnc(I)c1>>CC(C)Cn1c(-c2c(F)cccc2F)c(Cl)nc(-c2cn(C)cn2)c1=O,,ClCCl,,CC[Mg]Br,,test
US04933355,CCOC(=O)C(=O)c1csc(N)n1.O=C=Nc1ccccc1>>CCOC(=O)C(=O)c1csc(NC(=O)Nc2ccccc2)n1,,CN(C)C=O,,,,test
US20050075360A1,BrCCC(c1ccccc1)c1ccccc1.Cl.O=C1NC2(CCNCC2)C(=O)N1Cc1ccc(Br)cc1>>Cl.O=C1NC2(CCN(CCC(c3ccccc3)c3ccccc3)CC2)C(=O)N1Cc1ccc(Br)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04435566,C1CNCCN1.Clc1nc2c(c(N3CCCC3)n1)SCCC2>>C1CSc2c(nc(N3CCNCC3)nc2N2CCCC2)C1,,c1ccccc1,,,,test
US20020082421A1,CC(C)Oc1ccccc1N1CCN(CCNC(=O)CN2CCCCC2=O)CC1.Cl>>CC(C)Oc1ccccc1N1CCN(CCNC(=O)CN2CCCCC2=O)CC1.Cl,,Cc1ccccc1C,,O,O,test
US20120015978A1,CC(C)OC(=O)COc1cccc(N)c1.CCCCCCc1cnc2c(C(=O)O)cccc2c1>>CCCCCCc1cnc2c(C(=O)Nc3cccc(OCC(=O)OC(C)C)c3)cccc2c1,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100298339A1,CC(C)(C)OC(=O)NCC(=O)Nc1ccc(-c2cccc3nc(NC(=O)C4CC4)nn23)cc1>>NCC(=O)Nc1ccc(-c2cccc3nc(NC(=O)C4CC4)nn23)cc1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120142665A1,COc1cccc(-c2nc3cc(NC(=O)OC(C)(C)C)ccn3n2)c1>>COc1cccc(-c2nc3cc(N)ccn3n2)c1,,C1COCCO1,ClCCl,Cl,,test
US20120252801A1,CCNC(C)C(C)(C)O.O=CC=O>>CCN1CC(=O)OC(C)(C)C1C,,Cc1ccccc1,,,,test
US20070037976A1,CC(C[N+](=O)[O-])c1ccccc1>>CC(CN)c1ccccc1,[Pd],,,CO,,test
US20090306059A1,CCOC(=O)Cc1cn[nH]c1.Cc1ccc(S(=O)(=O)OC/C=C2/CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)CCC2O[Si](C)(C)C(C)(C)C)cc1>>CCOC(=O)Cc1cnn(C/C=C2/CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)CCC2O[Si](C)(C)C(C)(C)C)c1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20070015802A1,COc1cc(OC)c2c(=O)cc(-c3ccccc3Cl)oc2c1[C@@H]1CCN(C)[C@H]1C(=O)O>>CN1CC[C@@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@@H]1C(=O)O,,O,,Cl,c1ccncc1,test
US05753657,O=CNC1c2ccccc2-c2[nH]c(=O)c3nccn3c21>>CNC1c2ccccc2-c2[nH]c(=O)c3nccn3c21,,C1CCOC1,,CO,,test
US05731463,ClCC1CC1.OCCc1ccc(O)cc1>>Oc1ccc(CCOCC2CC2)cc1,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20160152610A1,CC(C)(C)OC(=O)N1CCN(CCCCl)CC1.c1ccc2c3c([nH]c2c1)CNCC3>>CC(C)(C)OC(=O)N1CCN(CCCN2CCc3c([nH]c4ccccc34)C2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120245344A1,CC(C)(C)OC(=O)N1CCC(c2ccc(Cn3ccc4cc(S(C)(=O)=O)cc([N+](=O)[O-])c43)nc2)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccc(Cn3ccc4cc(S(C)(=O)=O)cc(N)c43)nc2)CC1,O=[Pt],CO,,,,test
US20140171446A1,COc1ccc(C(=C(C)C)c2ccc(N)nc2)cc1.Cc1c(F)cncc1C(=O)O>>COc1ccc(C(=C(C)C)c2ccc(NC(=O)c3cncc(F)c3C)nc2)cc1,,CCOC(C)=O,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US20100029678A1,COC(=O)C1C[C@H]2O[C@H]2C1>>COC(=O)[C@H]1CC[C@H](O)C1,,COC(C)(C)C,,,,test
US20090062280A1,COC(=O)Cn1c(=O)c(C(C)(C)C)nc2ccc(OC)nc21>>COc1ccc2nc(C(C)(C)C)c(=O)n(CC(=O)O)c2n1,,CO,O,[Na+].[OH-],,test
US20130184284A1,COC(=O)Cl.Nc1cccc(-c2cnco2)c1>>COC(=O)Nc1cccc(-c2cnco2)c1,,C1CCOC1,,,,test
US20070124152A1,CC(C)OCCN.CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN2C(=O)c3ccccc3C2=O)c1=O>>CC(C)OCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN)c1=O,,CCO,O,NN,,test
US20050250769A1,CCOC(=O)C(=NO)C(C)=O.NCc1ccc(OC(F)(F)F)cc1>>CCOC(=O)c1nc(-c2ccc(OC(F)(F)F)cc2)[nH]c1C,,CC#N,,,,test
US04125615,CCn1cc(C(=O)O)c(=O)c2cnc(N3CCN(Cc4ccc(N)cc4)CC3)nc21.Cl>>CCn1cc(C(=O)O)c(=O)c2cnc(N3CCN(Cc4ccc(N)cc4)CC3)nc21.Cl,,CCO,,,,test
US20110190395A1,CC/C=C\C/C=C\C/C=C\C/C=C\CCSC(CC)C(=O)O.O=C(OO)c1cccc(Cl)c1>>CC/C=C\C/C=C\C/C=C\C/C=C\CCS(=O)C(CC)C(=O)O,,ClC(Cl)Cl,,,,test
US20110092459A1,C=CCN(N)CC(=O)OCC.O=C=NCc1ccccc1>>C=CCN(CC(=O)OCC)NC(=O)NCc1ccccc1,,C1CCOC1,CCOC(C)=O,,,test
US20080194549A1,CNC[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1CN(C(=O)c1ccc(OC)c(OCCCOC)c1)C(C)C.O=C(Cl)C1CC1>>COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN(C)C(=O)C2CC2)C(C)C)ccc1OC,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US05284847,N#Cc1csc2[nH]c(=O)c(=O)[nH]c12.O=S(=O)(Cl)Cl>>N#Cc1c(Cl)sc2[nH]c(=O)c(=O)[nH]c12,,CC(=O)O,,,,test
US05183897,CON=Cc1c(C(C)C)nc(C(C)C)c(CO)c1-c1ccc(F)cc1>>CON=Cc1c(C(C)C)nc(C(C)C)c(C=O)c1-c1ccc(F)cc1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20140249154A1,C=O.c1ccc(-c2csc(Nc3ncccn3)n2)nc1>>OCc1sc(Nc2ncccn2)nc1-c1ccccn1,,C1CCOC1,,CCN(CC)CC,,test
US06121480,Cc1cc(Br)ccc1C#N.Cc1ccc(C)c([Mg]Br)c1>>Cc1ccc(C)c(-c2ccc(C#N)c(C)c2)c1,Cl[Pd]Cl,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060058295A1,CN(C)CC(=O)O.Nc1ccc2cc(Br)cnc2n1>>CN(C)CC(=O)Nc1ccc2cc(Br)cnc2n1,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20110086834A1,Nc1cc(I)ccc1F.Nc1ncc(Cl)c(Cl)n1>>Nc1ncc(Cl)c(Nc2cc(I)ccc2F)n1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20060025414A1,CI.CNC(=S)N1CCOCC1c1nnn(-c2cccc(Cl)c2)n1>>CN=C(SC)N1CCOCC1c1nnn(-c2cccc(Cl)c2)n1,,CO,ClCCl,,,test
US20050148624A1,COC(=O)c1ccc(Cn2c(C(=O)OC)c(-c3ccccc3)c3cc(Cl)ccc3c2=O)cc1>>COC(=O)c1c(-c2ccccc2)c2cc(Cl)ccc2c(=O)n1Cc1ccc(C(=O)O)cc1,,C1CCOC1,,CO,[Na+].[OH-],test
US20080020148A1,CCCC1CCC(c2cc(C=CC(C)=O)c(OCOCCOC)c(F)c2F)CC1>>CCCC1CCC(c2cc(CCC(C)O)c(O)c(F)c2F)CC1,,C1CCOC1,,,,test
US20150175530A1,COC(=O)[C@@H](NC(=O)c1ccc(C#CC#CC(CO)OC)cc1)C(C)(C)N.NO>>COC(C#CC#Cc1ccc(C(=O)N[C@H](C(=O)NO)C(C)(C)N)cc1)CO,,CC(C)O,,O,,test
US20100027192A1,CC(C)(Br)C(=O)Br.CCOP(=O)(CCCCCCCCCCCO)OCC>>CCOP(=O)(CCCCCCCCCCCOC(=O)C(C)(C)Br)OCC,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20100267722A1,O=S(=O)(Cl)c1ccc(F)cc1C(F)(F)F>>Fc1ccc(S)c(C(F)(F)F)c1,,C1COCCO1,,O,,test
US20030109536A1,CCCc1c(C(=O)OCC)n[nH]c1N.CCOC(=O)CC(C)=O>>CCCc1c(C(=O)OCC)nn2c(=O)cc(C)[nH]c12,,CC(=O)O,,,,test
US20110105436A1,Cc1cccc(Nc2nc(-c3ccnc(C#CCO)c3)cs2)c1>>Cc1cccc(Nc2nc(-c3ccnc(CCCO)c3)cs2)c1,[Pd],CCO,,,,test
US20050203146A1,CC(C)(C)c1ccccc1Oc1ccccc1[N+](=O)[O-]>>CC(C)(C)c1ccccc1Oc1ccccc1N,[Pd],C1CCOC1,CO,,,test
US20060052396A1,COC(=O)c1nc(-c2ccc(S(=O)(=O)N(C)C)cc2)cnc1N>>CN(C)S(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)O)n2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20090023773A1,N#Cc1ccccc1CBr.OC1CCNCC1>>N#Cc1ccccc1CN1CCC(O)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150374687A1,Clc1nc2ccccc2nc1-c1ccccc1.OC1CCNCC1>>OC1CCN(c2nc3ccccc3nc2-c2ccccc2)CC1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,,test
US04622418,CC1(C)CCC(C)(C)C1OCC(C)(C)[N+](=O)[O-]>>CC(C)(N)COC1C(C)(C)CCC1(C)C,[Ni],CO,,,,test
US07045545B1,CCOC(=O)Cc1cc(F)cc2ccoc12.CI>>CCOC(=O)C(C)c1cc(F)cc2ccoc12,,C1CCOC1,CCOC(C)=O,CC(C)[N-]C(C)C.[Li+],,test
US20090124596A1,CC(=O)Cl.N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccccc4)c3)c2=O)CC1>>CC(=O)N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccccc4)c3)c2=O)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20140288040A1,CC(C)(C)[S@@](=O)N[C@@H](CC(=O)O)c1ccc(Cl)c(Oc2ccccc2)c1F>>CC(C)(C)[S@@](=O)N[C@@H](CCO)c1ccc(Cl)c(Oc2ccccc2)c1F,,C1CCOC1,,B,,test
US20140128360A1,CC(C)N.CS(=O)(=O)c1cc(F)cc(OCCBr)c1>>CC(C)NCCOc1cc(F)cc(S(C)(=O)=O)c1,,CCO,,,,test
US03947473,CC(C)CCCC(C)CCCC(C)C=O>>CC(C)CCCC(C)CCCC(C)CO,,CCOCC,CCOCC,Cc1ccccc1,[Na+].[OH-],test
US04584290,O=C(OO)c1cccc(Cl)c1.O=CNC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)C(C=C(Br)Br)=CS[C@H]12>>O=CNC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(C=C(Br)Br)CS(=O)[C@H]12,,CCOC(C)=O,,,,test
US06759420B1,CO.N=C(NO)c1ccc(CC(C(=O)O)c2cccc(C(F)(F)F)c2)cc1>>COC(=O)C(Cc1ccc(C(=N)NO)cc1)c1cccc(C(F)(F)F)c1,,CO,,O=C(Cl)C(=O)Cl,,test
US05914339,CCOC(=O)C1(C(=O)OCC)Oc2ccc(CC(C)N(CC(O)c3cccc(Cl)c3)C(=O)OC(C)(C)C)cc2O1>>CC(Cc1ccc2c(c1)OC(C(=O)O)(C(=O)O)O2)N(CC(O)c1cccc(Cl)c1)C(=O)OC(C)(C)C,,O,,CO,[Na+].[OH-],test
US20040147529A1,CCOC(=O)CN1CCN(C(=O)CC(c2ccccc2)c2ccccc2)CC1>>O=C(O)CN1CCN(C(=O)CC(c2ccccc2)c2ccccc2)CC1,,CO,O,[Li+].[OH-],,test
US20030125370A1,Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1C(=O)O.O[C@H]1CN[C@@H](CNC2CC2)C1>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1C(=O)N1C[C@H](O)C[C@@H]1CNC1CC1,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20150133446A1,COc1cc(O)c(NC(=O)c2cn3nc(Br)sc3n2)c(O)c1>>COc1cc(O)c2nc(-c3cn4nc(Br)sc4n3)oc2c1,,CC(=O)O,,O=C(O)C(F)(F)F,,test
US20160031892A1,CC(C)(O)CCO.CS(=O)(=O)Cl>>CC(C)(O)CCOS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20060135484A1,CC(=O)OC(C)(C)C.CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc(C)c(S(N)(=O)=O)s1>>CC(=O)O.CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc(C)c(S(N)(=O)=O)s1,,C1COCCO1,Cl,,,test
US20080070935A1,O=P(Cl)(Cl)Cl.[O-][n+]1ccc2cc(F)ccc2c1>>Fc1ccc2c(Cl)nccc2c1,,ClC(Cl)Cl,,[Na+].[OH-],,test
US20070049632A1,Cc1noc(C)c1CCl.Cn1[nH]c(=O)c2c1[C@]1(C)CC[C@H]2C1(C)C>>Cc1noc(C)c1Cn1c(=O)c2c(n1C)[C@]1(C)CC[C@H]2C1(C)C,,CN(C)C=O,,,,test
US04552703,C=CCC1=C(C)[C@@H](O)CC1=O.O=[N+]([O-])O>>C=CCC1=C(C)[C@@H](O[N+](=O)[O-])CC1=O,,ClC(Cl)Cl,,CC(=O)OC(C)=O,,test
US20130210803A1,CC(C)=O.Cc1ccc2c(c1)CC(c1ccc(C)nc1)CN2N=O>>CC(C)=NN1CC(c2ccc(C)nc2)Cc2cc(C)ccc21,[Zn],,,O,[Cl-].[NH4+],test
US20060211693A1,CCOc1cc(C#N)ccc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)Cl.Cl.O=C(CN1CCNCC1)N1CCOCC1>>CCOc1cc(C#N)ccc1C1=N[C@@H](c2ccc(Cl)cc2)[C@@H](c2ccc(Cl)cc2)N1C(=O)N1CCN(CC(=O)N2CCOCC2)CC1.Cl,,ClCCl,O,CCN(C(C)C)C(C)C,,test
US04861785,O=C(c1ccc(F)cc1)N1CC1.c1ccc2oc(NC3CCNCC3)nc2c1>>O=C(NCCN1CCC(Nc2nc3ccccc3o2)CC1)c1ccc(F)cc1,,Cc1ccccc1,,,,test
US20110312936A1,C[Si](C)(C)C(F)(F)F.Clc1nccc2ccc(I)cc12>>FC(F)(F)c1ccc2ccnc(Cl)c2c1,[Cu]I,CCOC(C)=O,CN1CCCC1=O,[F-].[K+],,test
US20090018180A1,CCOC(=O)CSc1cc(Cl)cc(Cl)c1.NCCN>>Clc1cc(Cl)cc(SCC2=NCCN2)c1,,Cc1ccccc1,,C[Al](C)C,,test
US05494666,COc1ccc(CN2C(=O)[C@@H]3[C@H]2[C@H](CC(=O)COCC[Si](C)(C)C)CN3C(=O)OC(C)(C)C)cc1OC>>CC(C)(C)OC(=O)N1C[C@@H](CC(=O)COCC[Si](C)(C)C)[C@H]2NC(=O)[C@H]21,,CCOC(C)=O,,,,test
US20070244103A1,COc1ccc2ncc(Cl)c(C(O)CN3C4CCC3CC(NC(=O)OC(C)(C)C)C4)c2n1>>COc1ccc2ncc(Cl)c(C(O)CN3C4CCC3CC(N)C4)c2n1,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US04133889,CCOC(=O)c1cc(=O)c2c(OCC(O)COc3cccc(O)c3C(C)=O)cccc2o1.COC(OC)N(C)C>>CCOC(=O)c1cc(=O)c2c(OCC(O)COc3cccc(O)c3C(=O)C=CN(C)C)cccc2o1,,CO,,Cc1ccccc1C,,test
US20100022468A1,CCCC(CCC)C(=O)Cl.CCOC(=O)[C@H](CC)NP1(=O)OC[C@H]2O[C@@H](n3ccc(N)nc3=O)[C@](C)(O)[C@@H]2O1>>CCCC(CCC)C(=O)Nc1ccn([C@@H]2O[C@@H]3COP(=O)(N[C@@H](CC)C(=O)OCC)O[C@H]3[C@@]2(C)O)c(=O)n1,CN(C)c1ccncc1,C1CCOC1,CN(C)C=O,CCN(CC)CC,,test
US20160152626A1,CNC(C)(C)C.COc1cc2c(cc1CC(C)C)-c1c(c(C(=O)O)nn1-c1ccsc1)CO2>>COc1cc2c(cc1CC(C)C)-c1c(c(C(=O)N(C)C(C)(C)C)nn1-c1ccsc1)CO2,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100121048A1,CC#N.CC(C)(Br)Br.O=C1CN(Cc2ccccc2)C(=O)C(Cc2ccc(O)cc2)N1>>O=C1CN(Cc2ccccc2)C(=O)C(Cc2ccc(OCCCBr)cc2)N1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070010511A1,CNCCOC.COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2OCc2ccc(C)c(C(=O)Cl)c2)cc1>>COCCN(C)C(=O)c1cc(COC2CN(C(=O)OC(C)(C)C)CCC2c2ccc(OCCCOCc3ccccc3OC)cc2)ccc1C,,Cc1ccccc1,,,,test
US20100076026A1,Fc1ccc2c(Cl)n(-c3ccc(Cl)cc3)nc2c1.Nc1cccc(Cl)c1>>Fc1ccc2c(Nc3cccc(Cl)c3)n(-c3ccc(Cl)cc3)nc2c1,,CN1CCCC1=O,,,,test
US20020156081A1,Nc1ccc(Br)cc1.c1ccc(CC2CO2)cc1>>OC(CNc1ccc(Br)cc1)Cc1ccccc1,,CO,,,,test
US20100331334A1,Cn1cnc2c(Cl)c(Br)c(C(=O)O)nc21.Nc1ccc(I)cc1F>>Cn1cnc2c(Cl)c(Nc3ccc(I)cc3F)c(C(=O)O)nc21,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20040122063A1,COC(=O)[C@@H]1CC[C@H](NC(=O)OC(C)(C)C)[C@H](NC(=O)c2nc3c(s2)CN(C)CC3)C1.Cl.O=C(O)c1cc2cc(Cl)ccc2[nH]1>>COC(=O)[C@@H]1CC[C@H](NC(=O)c2cc3cc(Cl)ccc3[nH]2)[C@H](NC(=O)c2nc3c(s2)CN(C)CC3)C1.Cl,,C1COCCO1,,,,test
US20060178532A1,CC(C)=O.NNC(=O)c1ccccc1>>CC(C)NNC(=O)c1ccccc1,,CCCCCC,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20020016463A1,CC1CNCC(C)N1.Cc1cccc(C)c1NC(=O)CCl>>Cc1cccc(C)c1NC(=O)CN1CC(C)NC(C)C1,,CCO,,CC(C)NC(C)C,,test
US04375475,CC(=O)CC(O)C=Cc1ccc(Cl)cc1Cl.O=C(Br)CBr>>CC(=O)CC(C=Cc1ccc(Cl)cc1Cl)OC(=O)CBr,,CCOCC,,c1ccncc1,,test
US20100305122A1,N#CCCNC1CC1.NS(=O)(=O)c1ccc(OCC2(F)CCC(=O)CC2)c([N+](=O)[O-])c1>>N#CCCN(C1CC1)C1CCC(F)(COc2ccc(S(N)(=O)=O)cc2[N+](=O)[O-])CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090105227A1,COCn1c(-c2ccccc2OCc2ccccc2)c(C2CCCCC2)c2sc(C(=O)OC)c(C=O)c21>>COCn1c(-c2ccccc2O)c(C2CCCCC2)c2sc(C(=O)OC)c(C)c21,,CCOC(C)=O,,,,test
US20090239810A1,COc1ccccc1SC.O=C(OO)c1cccc(Cl)c1>>COc1ccccc1S(C)(=O)=O,,ClCCl,,O,,test
US20070106095A1,CC=C(CC)c1ccc(O)c(C=O)c1.C[Mg]Br>>CC=C(CC)c1ccc(O)c(C(C)O)c1,,C1CCOC1,,,,test
US20070054896A1,O=C(Cl)OCc1ccccc1.O=[N+]([O-])c1ccc(OC2CCN(Cc3ccccc3)C2)cc1CS(=O)(=O)c1cccc2ccccc12>>O=C(OCc1ccccc1)N1CCC(Oc2ccc([N+](=O)[O-])c(CS(=O)(=O)c3cccc4ccccc34)c2)C1,,c1ccccc1,,[Na+].[OH-],,test
US20110021521A1,FC(F)(F)c1nnc2ccc(Br)cn12.OB(O)c1ccc(C2CC2)cc1>>FC(F)(F)c1nnc2ccc(-c3ccc(C4CC4)cc3)cn12,,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20160096839A1,C=CC[C@H](NC(=O)OC(C)(C)C)c1cccc(-c2c(N)cnn2C)c1.C=C[C@@H](C)C(=O)O>>C=CC[C@H](NC(=O)OC(C)(C)C)c1cccc(-c2c(NC(=O)[C@H](C)C=C)cnn2C)c1,,CCOC(C)=O,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20040157891A1,COc1ccc(-c2oc(C(=O)C(C)C)nc2-c2ccc(OCCO[Si](C)(C)C(C)(C)C)cc2)cc1>>COc1ccc(-c2oc(C(=O)C(C)C)nc2-c2ccc(OCCO)cc2)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100152175A1,OCC12CCCN1CCN(Cc1ccccc1)C2>>OCC12CCCN1CCNC2,[Pd],CO,,O=C[O-].[NH4+],,test
US20090042929A1,NCc1ccccc1.O=C(O)c1ccc(OCC(=O)C23CC4CC(CC(C4)C2)C3)cc1>>O=C(NCc1ccccc1)c1ccc(OCC(=O)C23CC4CC(CC(C4)C2)C3)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US20040024214A1,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CCO)Cn1cnc2c(=O)[nH]c(N)nc21>>CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CCOC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)Cn1cnc2c(=O)[nH]c(N)nc21,CN(C)c1ccncc1,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05494928,CC(C)c1cc2[nH]ccc2cc1F.C[C@@H]1CO1>>CC(C)c1cc2c(ccn2C[C@@H](C)O)cc1F,,C1CCOC1,CCOCC,O,[H-].[Na+],test
US20120058989A1,COc1ccc(CO[C@@H]2C[C@@H](CO)N(C(=O)OCc3ccccc3)C2)cc1>>COc1ccc(CO[C@@H]2C[C@@H](C=O)N(C(=O)OCc3ccccc3)C2)cc1,,O,,CC(=O)O,[Na+].[OH-],test
US05962462,C=CCBr.N#CCc1cccc(Cl)c1>>C=CCC(C#N)c1cccc(Cl)c1,,C1CCOC1,,[H-].[Na+],,test
US05393459,CCCCCC[C@H](F)CO.COC(=O)c1ccc(O)cc1>>CCCCCC[C@H](F)COc1ccc(C(=O)O)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140162985A1,C=C1CCCc2cc(OC)ncc21.Cc1ccc(S(=O)(=O)OI(O)c2ccccc2)cc1>>COc1cc2c(cn1)CC(=O)CCC2,,CO,O,,,test
US20020058665A1,COC(=O)c1cccnc1-c1ccc(F)cc1.O=C(OO)c1cccc(Cl)c1>>COC(=O)c1ccc[n+]([O-])c1-c1ccc(F)cc1,,ClCCl,,,,test
US20010046975A1,CCN.C[Si](C)(C)c1cccc(Cl)c1N=C=O>>CCNC(=O)Nc1c(Cl)cccc1[Si](C)(C)C,,Cc1ccccc1,,CCOC(C)=O,,test
US20080039440A1,Clc1cc(Cl)ncn1.Oc1ccc2[nH]ccc2c1>>Clc1cc(Oc2ccc3[nH]ccc3c2)ncn1,,CC(C)=O,O,[Na+].[OH-],,test
US07396844B1,COC(=O)CCOc1cccc(C#N)c1>>N#Cc1cccc(OCCC(=O)O)c1,,Cl,,,,test
US05616610,CCC=O.COc1ccc(F)c2c1C[C@@H](NC1CCCCC1)CO2>>CCCN(C1CCCCC1)[C@H]1COc2c(F)ccc(OC)c2C1,,CO,,[BH3-]C#N.[Na+],,test
US20110251184A1,BrCCCBr.CCOC(=O)c1c[nH]c(C(=O)OCC)c1>>CCOC(=O)c1cc(C(=O)OCC)n(CCCBr)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060167266A1,CC#CCO.CS(=O)(=O)c1nsc(-c2cccc(Cl)c2)n1>>CC#CCOc1nsc(-c2cccc(Cl)c2)n1,,CN(C)C=O,,[H-].[Na+],,test
US20150284411A1,COc1c(F)cc(F)cc1-c1ccc(-c2nc3nc(OC4COC5C4OC[C@@H]5O)[nH]c3cc2Cl)cc1>>Oc1c(F)cc(F)cc1-c1ccc(-c2nc3nc(OC4COC5C4OC[C@@H]5O)[nH]c3cc2Cl)cc1,,CN(C)C=O,,[Cl-].[Li+],,test
US20100072887A1,COB(OC)OC.c1ccc2c(c1)[se]c1ccccc12>>OB(O)c1cccc2c1[se]c1ccccc12,,CCOCC,,Cl,[Li]CCCC,test
US20130165483A1,N.O=C(O)c1cc(-c2ccnc(Cl)c2)nn1-c1ccccc1Cl>>NC(=O)c1cc(-c2ccnc(Cl)c2)nn1-c1ccccc1Cl,,ClCCl,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US04096336,COC(=O)CCCc1ccccc1CC1(Cl)C(=O)CCCC1=O>>COC(=O)CCCc1ccccc1CC1=CCCC1=O,,Cc1ccccc1C,,O=C([O-])[O-].[Na+].[Na+],,test
US20110166133A1,NC(CO)c1cccc(F)c1.O=C(Cl)CCl>>O=C(CCl)NC(CO)c1cccc(F)c1,,C1CCOC1,,CCN(CC)CC,,test
US20090176804A1,Cc1cccc2c1cc(-c1ccc(Cl)c(S(=O)(=O)NC3CCCCC3)c1)n2C(=O)OC(C)(C)C>>Cc1cccc2[nH]c(-c3ccc(Cl)c(S(=O)(=O)NC4CCCCC4)c3)cc12,,ClCCl,,,,test
US20120208817A1,NC(N)=O.O=C(Cc1ccccc1)c1ccccc1.O=Cc1ccc(C(=O)O)cc1>>O=C1NC(c2ccccc2)=C(c2ccccc2)C(c2ccc(C(=O)O)cc2)N1,,CCO,,Cl,,test
US20120101083A1,CC1(C)OCC(=O)CO1.Cc1c(-c2noc(-c3cnc(NC(C)C)c(C#N)c3)n2)ccc2c1CCNC2.Cl>>Cc1c(-c2noc(-c3cnc(NC(C)C)c(C#N)c3)n2)ccc2c1CCN(C(CO)CO)C2.Cl,,ClCCl,,O=C([O-])O.[Na+],,test
US20120077781A1,Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCCCCCC(=O)O)c2cc1N[C@H]1CCN(C(=O)OC(C)(C)C)C1.O=C(O)C(F)(F)F>>Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCCCCCC(=O)O)c2cc1N[C@H]1CCNC1.O=C(O)C(F)(F)F,,O,,,,test
US20090233907A1,CN1CCCC1c1ccc2nc(C(=O)O)cn2c1.NC1CCC(n2c(=O)c3cc(F)cnc3n(C3CCSCC3)c2=O)CC1>>CN1CCCC1c1ccc2nc(C(=O)N[C@@H]3CC[C@H](n4c(=O)c5cc(F)cnc5n(C5CCSCC5)c4=O)CC3)cn2c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100204196A1,CN.COc1cc2c(cc1Nc1nc(Nc3cccc(F)c3C(N)=O)c3ccnc-3[nH]1)NCC2.O=C(Cl)CBr>>CNCC(=O)N1CCc2cc(OC)c(Nc3nc(Nc4cccc(F)c4C(N)=O)c4ccnc-4[nH]3)cc21,,C1CCOC1,,,,test
US20040167335A1,COc1ccc(-c2nn3ccc(NC4CCCC4)cc3c2-c2ccnc(NC3CCCC3)n2)cc1>>Oc1ccc(-c2nn3ccc(NC4CCCC4)cc3c2-c2ccnc(NC3CCCC3)n2)cc1,,ClCCl,,BrB(Br)Br,,test
US20150111866A1,C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1nc(N2CC(F)C2)ncc1B1OC(C)(C)C(C)(C)O1.Cc1cc(C(=O)OC(C)(C)C)ccc1-c1cnc(C)c(Cl)c1>>Cc1cc(C(=O)OC(C)(C)C)ccc1-c1cnc(C)c(-c2cnc(N3CC(F)C3)nc2CN2C(=O)O[C@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H]2C)c1,Cl[Pd]Cl,O,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20120316147A1,CC(C)(C)OC(=O)NC(C)(C)C(N)=S.COC(C)(OC)N(C)C>>CC(=NC(=S)C(C)(C)NC(=O)OC(C)(C)C)N(C)C,,ClCCl,,,,test
US20060100229A1,CCCn1nc2c(N)nc3ccccc3c2c1CCc1ccccc1>>CCCn1nc2c(N)nc3c(c2c1CCC1CCCCC1)CCCC3,O=[Pt]=O,O=C(O)C(F)(F)F,,,,test
US20020007066A1,C#CCO.Cc1nc2ncc(C(=O)NCc3ccc(Cl)cc3)c(O)c2cc1Br>>Cc1nc2ncc(C(=O)NCc3ccc(Cl)cc3)c(O)c2cc1C#CCO,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,CCN(CC)CC,,test
US20070213339A1,CCOC=C(C(=O)OCC)C(=O)c1cc(F)c(F)c(OC(F)(F)F)c1F.Nc1cccc(CN2CCCCC2)c1>>CCOC(=O)C(=CNc1cccc(CN2CCCCC2)c1)C(=O)c1cc(F)c(F)c(OC(F)(F)F)c1F,,CCO,,,,test
US20150119373A1,CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC[C@@H]2[C@H]4[C@H](C5(C)CC5)CC[C@]4(C(=O)O)CC[C@]23C)C1(C)C.O=S(Cl)Cl>>CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC[C@@H]2[C@H]4[C@H](C5(C)CC5)CC[C@]4(C(=O)Cl)CC[C@]23C)C1(C)C,,Cc1ccccc1,,,,test
US06194461B1,CC(C)(N)CO[Si](C)(C)C(C)(C)C.O=Cc1ccc(F)cc1F>>CC(C)(CO[Si](C)(C)C(C)(C)C)NCc1ccc(F)cc1F,,Cc1ccccc1,,,,test
US20090318431A1,NCc1c(F)cc([N+](=O)[O-])cc1CO.O=C(n1ccnc1)n1ccnc1>>CN1C(=O)OCc2cc([N+](=O)[O-])cc(F)c21,,CC#N,O,,,test
US20080200501A1,NC(=S)c1nn(-c2ccc(F)cc2F)c2c1C1CCC2C1.O=C(CBr)c1ccccc1>>Fc1ccc(-n2nc(-c3nc(-c4ccccc4)cs3)c3c2C2CCC3C2)c(F)c1,,C1CCOC1,,,,test
US04797496,CC(C)COC(=O)CC1CO1.O=C1CNC(c2ccccc2)N1>>CC(C)CN1CC(=O)NC1c1ccccc1.CC(O)CC(=O)[O-],,CC(C)=O,O,,,test
US20120136176A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.Nc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)Nc1ccccc1,,C1CCOC1,,CCN=C=NCCCN(C)C,Cl,test
US20130178629A1,COC(=O)c1c(C(=O)OC)c(-c2ccc(Cl)cc2)n2c1Cc1c(n(C)c3ccccc13)C2>>Cn1c2c(c3ccccc31)Cc1c(CO)c(CO)c(-c3ccc(Cl)cc3)n1C2,,CCOCC,ClCCl,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040072818A1,COc1ccc2c(N3CCNCC3)ccnc2c1C.O=C=Nc1ccc(F)cc1>>COc1ccc2c(N3CCN(C(=O)Nc4ccc(F)cc4)CC3)cc(C)nc2c1,,C1CCOC1,,CCCCCC,CCOC(C)=O,test
US20080194616A1,CCCCc1nc2ccccn2c(=O)c1-c1ccc(NC2CCN(C(=O)OC(C)(C)C)C2)cc1.Cl>>CCCCc1nc2ccccn2c(=O)c1-c1ccc(NC2CCNC2)cc1.Cl,,C1COCCO1,,,,test
US20100144694A1,CC1(C)NN(C2C3CC4CC(C3)CC2C4)C1=O.CCOC(=O)CBr>>CCOC(=O)CN1N(C2C3CC4CC(C3)CC2C4)C(=O)C1(C)C,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120122863A1,CCCC[C@@H](C(=O)OC)n1c(=O)c2ccc(OC)cc2n(Cc2cn(C)c3cccc(C)c23)c1=O>>CCCC[C@@H](C(=O)O)n1c(=O)c2ccc(OC)cc2n(Cc2cn(C)c3cccc(C)c23)c1=O,,C1COCCO1,O,,,test
US20160143277A1,CC#Cc1cc(F)c(C2C(=O)C3CCC(C3)C2=O)c(OC)c1.O=C(Cl)c1ccccc1>>CC#Cc1cc(F)c(C2=C(OC(=O)c3ccccc3)C3CCC(C3)C2=O)c(OC)c1,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20060223789A1,CI.CN=C(NN)N1CCN(C=O)CC1>>CN=C(N(C)N)N1CCN(C=O)CC1,,CC#N,,,,test
US20070179151A1,COc1ccc(C(=O)O)c(CC#N)c1.Nc1cc[nH]n1>>COc1ccc2c(=O)[nH]c(Nc3cc[nH]n3)cc2c1,,CC(=O)O,,,,test
US20090099169A1,C#CC(C)(C)Oc1ccc(Cl)cc1C(=O)OC.CCN(CC)c1ccccc1>>COC(=O)c1cc(Cl)cc2cc(C(C)C)oc12,,CCOCC,,[Cs+].[F-],,test
US20130029938A1,CCCCC1(CCCC)CSc2cc(C(=O)OC)c(OC)cc2C(c2ccccc2)=N1>>CCCCC1(CCCC)CSc2cc(CO)c(OC)cc2C(c2ccccc2)=N1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100292210A1,COc1cc([N+](=O)[O-])ccc1-n1cncc1C>>COc1cc(N)ccc1-n1cncc1C,[Pd],CCOC(C)=O,,,,test
US20150307453A1,Nc1cc(Cl)cc(Cl)c1.S=C(Cl)Cl>>S=C=Nc1cc(Cl)cc(Cl)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20060094750A1,CC(C)(C)CC(=O)Cl.CCS(=O)(=O)c1ccc(NCC2CCOCC2)c(N)c1>>CCS(=O)(=O)c1ccc2c(c1)nc(CC(C)(C)C)n2CC1CCOCC1,,CCOC(C)=O,,,,test
US20100094000A1,CC(=O)c1ccc(C)cc1.CCOC(C)=O>>CC(=O)CC(=O)c1ccc(C)cc1,,C1CCOC1,,Cl,[H-].[Na+],test
US20060135561A1,C=CC(=O)OCC.NCCc1ccccc1>>CCOC(=O)CCNCCc1ccccc1,,CCO,,,,test
US20070015764A1,O=[N+]([O-])O.[O-][n+]1c(CC(F)(F)F)cccc1CC(F)(F)F>>O=[N+]([O-])c1cc(CC(F)(F)F)[n+]([O-])c(CC(F)(F)F)c1,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20030199440A1,CC(C)(C)OC(=O)CNS(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1.Cl.N=C(N)N>>CC(C)(C)OC(=O)CNS(=O)(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1.Cl,,CS(C)=O,O,[H-].[Na+],,test
US20030139409A1,BrCc1ccccc1.O=C(O)c1cccc2nc3ccc4c(O)cccc4c3nc12>>O=C(O)c1cccc2nc3ccc4c(OCc5ccccc5)cccc4c3nc12,,CCO,CCOC(C)=O,[Na+].[OH-],,test
US20120322784A1,O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.OC1CCC1>>O=C(Oc1ccc([N+](=O)[O-])cc1)OC1CCC1,,ClCCl,,O,c1ccncc1,test
US05541324,C1CCNC1.Fc1cccc2c1NCc1c(-c3noc(C4CC4)n3)ncn1-2.O=C(Cl)Cl>>O=C(N1CCCC1)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2cccc(F)c21,,C1CCOC1,O,CCN(C(C)C)C(C)C,,test
US05053500,CC(C)(C)OC(=O)NC1C=C(C(=O)O)N2C(=O)C[C@H]2S1.CC=O.CCN(CC)CC>>CCNCC1=C(C(=O)O)N2C(=O)C(N)[C@H]2SC1,,CO,,[BH3-]C#N.[Na+],,test
US20100094000A1,CCOC(=O)Cn1nc(C)cc1-c1ccc(F)cc1.O=C1CCC(=O)N1Br>>CCOC(=O)Cn1nc(C)c(Br)c1-c1ccc(F)cc1,,CN(C)C=O,,,,test
US05189054,CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1NCC(=O)OCCCC(=O)c1ccccc1>>O=C(O)CN(CC(=O)c1ccccc1)c1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12,,C1CCOC1,O,[Li+].[OH-],,test
US20110118265A1,CC(C)=CCC/C(C)=C/CC/C(C)=C/CSC[C@H](N)C(=O)O.O=C(Cl)N1CCOCC1>>CC(C)=CCC/C(C)=C/CC/C(C)=C/CSC[C@H](NC(=O)N1CCOCC1)C(=O)O,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20010051657A1,COC(=O)CC(=O)Nc1cc(C)c(Oc2ccc(O)c(C(C)C)c2)c(C)c1>>Cc1cc(NC(=O)CC(=O)O)cc(C)c1Oc1ccc(O)c(C(C)C)c1,,CO,O,[K+].[OH-],,test
US04052514,NO.O=C(Cl)Cc1ccc(-c2ccc(F)cc2F)c(F)c1>>O=C(Cc1ccc(-c2ccc(F)cc2F)c(F)c1)NO,,CCOCC,O,,,test
US20100190764A1,COC(=O)C1=CCN(C2CCC3(Cc4ccccc4Oc4ccccc43)C2)CC1>>O=C(O)C1=CCN(C2CCC3(Cc4ccccc4Oc4ccccc43)C2)CC1,,CO,,O,[Li+].[OH-],test
US20020160996A1,COc1c(C)c(C)c(NC(=O)OC(C)(C)C)c(C)c1Br.Cc1ccc(C(=O)C(C)C)cc1>>COc1c(C)c(C)c(NC(=O)OC(C)(C)C)c(C)c1C(O)(c1ccc(C)cc1)C(C)C,,C1CCOC1,,O,[Li]CCCC,test
US20110082133A1,CCCCN(C)Cc1c(Cl)cc(Cl)c(=O)n1CCc1ccc(C(=O)OC(C)(C)C)cc1>>CCCCN(C)Cc1c(Cl)cc(Cl)c(=O)n1CCc1ccc(C(=O)O)cc1,,CCOC(C)=O,,Cl,,test
US20080081817A1,NN.O=Cc1c[n+]([O-])ccc1[N+](=O)[O-]>>[O-][n+]1ccc2[nH]ncc2c1,,CCO,,O,,test
US20150282482A1,COC(=O)CS.COC(=O)c1ccc([N+](=O)[O-])c(C=O)c1>>COC(=O)c1ccc2sc(C(=O)OC)cc2c1,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20070265225A1,N[C@@H]1c2ccccc2C[C@@H]1O.O=C(Cl)CCl>>O=C(CCl)N[C@@H]1c2ccccc2C[C@@H]1O,,ClCCl,,CCN(CC)CC,,test
US06262103B1,CC(C)C[Mg]Cl.CC1(C)CC(=O)c2c(S(C)(=O)=O)sc(C#N)c2C1>>CC(C)Cc1sc(C#N)c2c1C(=O)CC(C)(C)C2,,C1CCOC1,,,,test
US20070219186A1,O=C(Cl)C(=O)Cl.O=C(O)c1cccc(C(F)F)c1>>O=C(Cl)c1cccc(C(F)F)c1,CN(C)C=O,C1COCCO1,,,,test
US05998624,CNC(C)C(C)F.O=C(O)c1cc2ccccc2c(-c2ccccc2I)n1>>CC(CCF)N(C)C(=O)c1cc2ccccc2c(-c2ccccc2I)n1,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20060040988A1,CS(=O)(=O)c1ccc(B(O)O)cc1.Cc1ccnc(Cl)c1>>Cc1ccnc(-c2ccc(S(C)(=O)=O)cc2)c1,,CN(C)C=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20050101063A1,CN(C)C=O.Ic1ccc(I)cc1>>O=Cc1ccc(I)cc1,,CCOCC,,[Li]CCCC,,test
US20020132319A1,O=C(OC1CCCCC1)C(c1ccccc1)n1cnc2[nH]ncc2c1=S>>O=C(O)C(c1ccccc1)n1cnc2[nH]ncc2c1=S,,CO,,[K+].[OH-],,test
US20030195176A1,CCC(O)(CC)CCOC(C)(C)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>CCC(O)(CC)CCOC(C)(C)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150353553A1,CC(C)c1ccnc(-c2nc3nc(C#N)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1.[N-]=[N+]=[N-]>>CC(C)c1ccnc(-c2nc3nc(-c4nnn[nH]4)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1,,CN(C)C=O,,[Cl-].[NH4+],,test
US20120108574A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3c(/C=C/c4ccccc4)nc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1>>NC1(c2ccc(-c3c(CCc4ccccc4)nc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1,[Pd],C1CCOC1,CO,,,test
US20070259849A1,Cc1cc(C(=O)Nc2cc(NC(=O)c3cccc(C(C)(C)C#N)c3)ccc2C)nc(N2CCN(C(=O)OC(C)(C)C)CC2)n1>>Cc1cc(C(=O)Nc2cc(NC(=O)c3cccc(C(C)(C)C#N)c3)ccc2C)nc(N2CCNCC2)n1,,C1COCCO1,Cl,,,test
US20120208800A1,CC(=O)N1c2ccc(-c3ccc(C=O)cc3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C.CN>>CNCc1ccc(-c2ccc3c(c2)[C@H](NC(=O)OC(C)C)C[C@H](C)N3C(C)=O)cc1,,CO,,C1CCOC1,[BH4-].[Na+],test
US03991106,CCO.CCOC(=O)CCCCCCN(CCCC1CO1)S(C)(=O)=O>>CCOCC(O)CCCN(CCCCCCC(=O)O)S(C)(=O)=O,,O,,[Na+].[OH-],,test
US04859692,COC(=O)c1cccc(CN2CCOc3ccc([N+](=O)[O-])cc32)c1>>COC(=O)c1cccc(CN2CCOc3ccc(N)cc32)c1,[Pd],CCOC(C)=O,,,,test
US05880130,Cc1cccc(N)c1.OCCOc1ccc(Nc2cc(Cl)ncn2)cc1>>Cc1cccc(Nc2cc(Nc3ccc(OCCO)cc3)ncn2)c1,,CN1CCCC1=O,,,,test
US20140031360A1,Fc1cccc(F)c1-c1ccc2[nH]ncc2c1.II>>Fc1cccc(F)c1-c1ccc2[nH]nc(I)c2c1,,CN(C)C=O,,O,[K+].[OH-],test
US04426538,Cc1c([N+](=O)[O-])cc(Cl)c(Cl)c1[N+](=O)[O-]>>Cc1c(N)cc(Cl)c(Cl)c1N,[Pt],,,C1COCCN1,,test
US20040254156A1,COC(=O)Cc1ccccc1CNC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCc1ccccc1CC(=O)O,,C1CCOC1,O,[Li+].[OH-],,test
US20100048610A1,C=CCBr.O=C(CO)c1ccccc1>>C=CCOc1ccc(C(C)=O)cc1,,CC(C)=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20130217671A1,CCCC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1N[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1>>CCCC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1N[C@@H]1CC[C@@H](N)CC1,,C1CCOC1,,Cl,O,test
US20030018196A1,COC(=O)C(C)(C)c1ccc(C(=O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1>>COC(=O)C(C)(C)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1,,CO,,[BH4-].[Na+],,test
US20130274243A1,CCC(C)(C)c1ccc(NC(C)=O)c([N+](=O)[O-])c1>>CCC(C)(C)c1ccc(N)c([N+](=O)[O-])c1,,CO,,O,[Na+].[OH-],test
US20100197723A1,CC(C)n1ccc2ccccc21.NCCCN1CCCCC1.O=C(Cl)C(=O)Cl>>CC(C)n1cc(C(=O)C(=O)NCCCN2CCCCC2)c2ccccc21.Cl,,C1CCOC1,CCOCC,CCN(CC)CC,,test
US20160016968A1,CC(C)(C)c1nc(-c2cc(Cl)c(C3CC3)cn2)no1.FC1(F)CNCC1(F)F>>CC(C)(C)c1nc(-c2cc(N3CC(F)(F)C(F)(F)C3)c(C3CC3)cn2)no1,,O=S1(=O)CCCC1,,Cl,O=C([O-])[O-].[K+].[K+],test
US04709069,O=C1OCCO1.OCCOCCO>>O=C1OCCO1.O=C=O,,OCCOCCO,,,,test
US06080781,O=C1CCCc2cc(O)ccc21.O=Cc1ccccc1>>O=C1C(=Cc2ccccc2)CCc2cc(O)ccc21,,O,,CO,Cl,test
US20110076291A1,CC(C)n1ncnc1-c1nc2c(s1)CCOc1cc(C3CN(C(=O)O)C3)ccc1-2>>CC(C)n1ncnc1-c1nc2c(s1)CCOc1cc(C3CNC3)ccc1-2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030232850A1,FC(F)(F)c1ccc(CBr)cc1.O=C(OCc1ccccc1)N1CCc2c([nH]c3ccccc23)C1>>O=C(OCc1ccccc1)N1CCc2c(n(Cc3ccc(C(F)(F)F)cc3)c3ccccc23)C1,,CN(C)C=O,,O,[H-].[Na+],test
US20080004309A1,CCOC(=O)C1C(=O)c2sc(-c3ccc(C(C)(C)C)cc3)nc2CN1Cc1ccc(OC)cc1OC>>CCOC(=O)c1ncc2nc(-c3ccc(C(C)(C)C)cc3)sc2c1O,,ClCCl,,O=S(Cl)Cl,,test
US04255432,CNCC1(O)CCN(Cc2ccccc2)CC1.O=C(Cl)Cl>>CN1CC2(CCN(Cc3ccccc3)CC2)OC1=O,,Cc1ccccc1,,ClCCl,O=C([O-])O.[Na+],test
US20150119241A1,CC(C)C1Cc2c(NC(=O)c3c(C(F)F)nn(C)c3Cl)cccc2C1(C)C.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CC(C)C1Cc2c(NC(=S)c3c(C(F)F)nn(C)c3Cl)cccc2C1(C)C,,C1COCCO1,,,,test
US20030171410A1,Cl.FC(F)(F)c1cnc(C(Cc2ccccc2)N=C(c2ccccc2)c2ccccc2)c(Cl)c1>>Cl.NC(Cc1ccccc1)c1ncc(C(F)(F)F)cc1Cl,,CCOCC,,,,test
US20120068170A1,CC1(C)c2ccccc2-c2cc3c(cc21)[nH]c1ccc(-c2cccc4c2oc2ccccc24)cc13.Clc1nc(-c2ccccc2)nc(-c2ccccc2)n1>>CC1(C)c2ccccc2-c2cc3c4cc(-c5cccc6c5oc5ccccc56)ccc4n(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3cc21,,CN(C)C=O,,[H-].[Na+],,test
US20110319394A1,CCn1c(=O)n(-c2ccc(O)cc2)c2ncccc21.C[Si](C)(C)CCOCn1c(Cl)nc2ccccc21>>CCn1c(=O)n(-c2ccc(Oc3nc4ccccc4n3COCC[Si](C)(C)C)cc2)c2ncccc21,,CN(C)C=O,,[H-].[Na+],,test
US20030224298A1,CCCCC1CCC(S(=O)(=O)CS(=O)(=O)C2CCC(CCCC)CC2)CC1.Cc1ccc(S(=O)(=O)N=[N+]=[N-])cc1>>CCCCC1CCC(S(=O)(=O)C(=[N+]=[N-])S(=O)(=O)C2CCC(CCCC)CC2)CC1,,ClCCl,,Cl,O,test
US20020165365A1,CCOC(=O)CNC(=O)CN1CCN(C(=O)OCc2ccccc2)CCN(C(=O)OCc2ccccc2)CCN(C(=O)OCc2ccccc2)CC1>>O=C(O)CNC(=O)CN1CCN(C(=O)OCc2ccccc2)CCN(C(=O)OCc2ccccc2)CCN(C(=O)OCc2ccccc2)CC1,,CO,,[Na+].[OH-],,test
US06630281B2,C1=CC2CCC1C2.O=C(O)C1CC2C=CC1C2.O=C1C=CC(=O)O1.OCC1CC2C=CC1C2>>C1=CC2CCC1C2.O=C(O)C1CC2C=CC1C2.O=C1C=CC(=O)O1.OCC1CC2C=CC1C2,,C1CCOC1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20130143870A1,Cl.c1ccc(CN2CCc3ncnc(-c4ccccc4)c3CC2)cc1>>Cl.c1ccc(-c2ncnc3c2CCNCC3)cc1,[Pd],CCO,,[H][H],,test
US20040254159A1,CC(=N)NO.COc1cc(-c2ccc3c(c2)Nc2ccc(CCC(=O)O)cc2NC3=O)ccc1[N+](=O)[O-]>>COc1cc(-c2ccc3c(c2)Nc2ccc(CCC(=O)ONC(C)=N)cc2NC3=O)ccc1[N+](=O)[O-],,CN(C)C=O,ClCCl,CC(C)N=C=NC(C)C,,test
US20140235628A1,CC(C)(C)OC(=O)Cc1ccc2c(c1)COC2=O>>O=C(O)Cc1ccc2c(c1)COC2=O,,O=C(O)C(F)(F)F,,,,test
US04083852,CCC(=O)CSCC(=O)OC>>CC1C(=O)CSCC1=O,,C1CCOC1,,[H-].[Na+],,test
US20050043301A1,CNC(=O)CN(OC)c1nc(-c2ccncc2)c(-c2ccc3ccccc3c2)c(=O)n1C.COc1cccc(C[Mg]Cl)c1>>COc1cccc(CC(=O)CNc2nc(-c3ccncc3)c(-c3ccc4ccccc4c3)c(=O)n2C)c1,,C1CCOC1,,CCOC(C)=O,O,test
US06288082B1,CCOc1cc2c(Cl)c(C#N)cnc2cc1OC.Nc1ccc2cn[nH]c2c1>>CCOc1cc2c(Nc3ccc4cn[nH]c4c3)c(C#N)cnc2cc1OC,,CCO,,O=C([O-])O.[Na+],,test
US20140171408A1,CC(C)(C)C(=O)Nc1ccncc1.CC(C)N(C(=S)SSC(=S)N(C(C)C)C(C)C)C(C)C>>CC(C)N(C(=S)Sc1cnccc1NC(=O)C(C)(C)C)C(C)C,,C1CCOC1,CCOC(C)=O,O,[Li]CCCC,test
US04802906,NC1CC1.NS(=O)(=O)c1ccccc1S(=O)(=O)Cl>>NS(=O)(=O)c1ccccc1S(=O)(=O)NC1CC1,,C1CCOC1,,,,test
US20100234395A1,CC(C)(C)OC(=O)N1CCC(c2nc(-c3ccc(F)cc3)c(-c3ccccc3)o2)CC1>>Fc1ccc(-c2nc(C3CCNCC3)oc2-c2ccccc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140336211A1,COC(=O)C(CN(c1ccccc1)c1ncccn1)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>COC(=O)C(N)CN(c1ccccc1)c1ncccn1,,CC(=O)OC(C)C,,Cl,,test
US20090131452A1,CC(C)(C)OC(=O)N1CCN(c2cc([N+](=O)[O-])ccc2OC(F)(F)F)CC1>>CC(C)(C)OC(=O)N1CCN(c2cc(N)ccc2OC(F)(F)F)CC1,[Pd],CC(=O)O,CCOC(C)=O,,,test
US04046900,CC(=O)N1CCC(C(=O)Cl)CC1.CC(C)(C)c1ccccc1>>CC(=O)N1CCC(C(=O)c2ccc(C(C)(C)C)cc2)CC1,,CC(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20150353477A1,CN(NC(=O)c1ccc(/C=C/C(c2cc(Cl)c(Cl)c(Cl)c2)C(F)(F)F)cc1C(F)(F)F)C(=O)OC(C)(C)C.Cl>>CNNC(=O)c1ccc(/C=C/C(c2cc(Cl)c(Cl)c(Cl)c2)C(F)(F)F)cc1C(F)(F)F.Cl,,C1COCCO1,,,,test
US05234936,FC(F)(F)c1nc(Cl)c2c(n1)CCCC2.O=C1CCC(=O)N1Br>>FC(F)(F)c1nc(Cl)c2c(n1)CCCC2Br,,ClC(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US05472964,Cc1ccc2sc(Cl)cc2n1.O=C1CCC(=O)N1Br>>Clc1cc2nc(CBr)ccc2s1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20090186913A1,CN1C(=O)NC(=O)C(C)(N)C1=O.O=C1OC(=O)c2c(F)c(F)c(F)c(F)c21>>CN1C(=O)NC(=O)C(C)(N2C(=O)c3c(F)c(F)c(F)c(F)c3C2=O)C1=O,,CC(=O)O,,CCN(CC)CC,Cl,test
US04547514,CCNCCN(CC)CC.O=C(Cl)N1CCC(Oc2cc(Cl)cc(Cl)c2)C1>>CCN(CC)CCN(CC)C(=O)N1CCC(Oc2cc(Cl)cc(Cl)c2)C1,,C1CCOC1,CC(C)=O,O=C(O)C(=O)O,,test
US20140128425A1,CCOC(=O)C(Cl)C(C)=O.Nc1ncc(Cl)cc1OCc1c(F)cccc1F>>CCOC(=O)c1c(C)nc2c(OCc3c(F)cccc3F)cc(Cl)cn12,,CCO,,,,test
US20110212943A1,COC(=O)c1ccc(CNC23CC4CC(CC(C4)C2)C3)cc1>>O=C(O)c1ccc(CNC23CC4CC(CC(C4)C2)C3)cc1,,CO,O,CC(=O)O,[Na+].[OH-],test
US04504584,CCCCCCCCCCCCCCCC(=O)N[C@@H](C)C(=O)N[C@H](CCC(=O)O)C(=O)OCc1ccccc1.O=C1CCC(=O)N1O>>CCCCCCCCCCCCCCCC(=O)N[C@@H](C)C(=O)N[C@H](CCC(=O)ON1C(=O)CCC1=O)C(=O)OCc1ccccc1,,C1CCOC1,ClC(Cl)Cl,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20060040917A1,COS(=O)(=O)OC.COc1cccc(-c2coc3cc(O)ccc3c2=O)c1>>COc1cccc(-c2coc3cc(OC)ccc3c2=O)c1,,CC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20070249642A1,CC(C)(C)[Si](C)(C)OCCCn1cc(C(F)(F)F)c(=O)[nH]c1=O>>O=c1[nH]c(=O)n(CCCO)cc1C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090093483A1,CC(C)(C)OC(=O)CN.CCOC(=O)C1=C(O)c2cc(OC)c(Br)cc2C2(CCOCC2)C1=O>>COc1cc2c(cc1Br)C1(CCOCC1)C(=O)C(C(=O)NCC(=O)OC(C)(C)C)=C2O,,C1COCCO1,,CCN(C(C)C)C(C)C,Cl,test
US04778796,Cc1ccc(C=CC(=O)NCCCCl)cn1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>Cc1ccc(C=CC(=O)NCCCN2CCN(C(c3ccccc3)c3ccccc3)CC2)cn1,,CCC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US05545644,CCI.CCS(=O)(=O)CCc1ccc2[nH]cc(C[C@H]3CCCN3)c2c1>>CCN1CCC[C@@H]1Cc1c[nH]c2ccc(CCS(=O)(=O)CC)cc12,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20090181965A1,BrBr.N#CCC1(c2ccc(Cl)cc2)CCCCC1=O>>N#CCC1(c2ccc(Cl)cc2)CCCC(Br)C1=O,,ClC(Cl)Cl,,,,test
US05075313,COc1ccc2[nH]c(C)c(C3C(=O)OC(C)(C)OC3=O)c2c1.COc1ccc2[nH]cc(CCC(=O)Nc3ccccc3C(=O)O)c2c1.Nc1ccccc1C(=O)O>>COc1ccc2[nH]c(CCc3nc4ccccc4c(=O)n3-c3ccccc3)cc2c1,,c1ccncc1,,,,test
US04695575,NC(N)=O.Nc1c(Cl)ncnc1NCCN1CCC(Cc2nc3ccccc3n2Cc2ccc(F)cc2)CC1>>Oc1nc2c(Cl)ncnc2n1CCN1CCC(Cc2nc3ccccc3n2Cc2ccc(F)cc2)CC1,,O,,,,test
US20030114508A1,CNC.COCCNC1=C(N(C)C(=O)CCl)C(=O)c2ccccc2C1=O>>COCCNC1=C(N(C)C(=O)CN(C)C)C(=O)c2ccccc2C1=O,,C1CCOC1,,O,,test
US20140303139A1,C[C@H](Nc1cc(C(N)=O)nc(Cl)n1)C(N)=O.OC1CCNCC1>>C[C@H](Nc1cc(C(N)=O)nc(N2CCC(O)CC2)n1)C(N)=O,,CC#N,,,,test
US04775675,CC(=O)N[C@@H](C(=O)O)C(C)(C)S.O=Cc1ccc(Cl)cc1>>CC(=O)N1[C@@H](c2ccc(Cl)cc2)SC(C)(C)[C@@H]1C(=O)O,,Cl,,,,test
US20090062366A1,C[C@H](c1cccc2ccccc12)N(CC1CCNC1)C(=O)OC(C)(C)C.O=C(Cl)c1ccccc1>>C[C@@H](NCC1CCN(C(=O)c2ccccc2)C1)c1cccc2ccccc12.Cl,,C1CCOC1,,O=C([O-])O.[Na+],,test
US05278316,CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)O.NCCc1nc2ccccc2[nH]1>>CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NCCc1nc2ccccc2[nH]1,,CCN(CC)CC,,Cl,Cl,test
US20020160907A1,O=C(Cl)C=Cc1cccc2ccccc12>>O=CC=Cc1cccc2ccccc12,,CC(C)=O,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US05463129,COc1cc(O)c([N+](=O)[O-])cc1[N+](=O)[O-]>>O=[N+]([O-])c1cc([N+](=O)[O-])c(O)cc1O,,CN(C)C=O,,Cl,Cl,test
US20140107100A1,COC(=O)OC.C[C@H]1CCCC(=O)C1>>COC(=O)C1CC[C@H](C)CC1=O,,CCOCC,,CO,[H-].[Na+],test
US20100323994A1,COc1ccc(CN(c2cc(Cl)nn3c(C(=O)Nc4ccncn4)cnc23)C2CC2)cc1.N[C@H]1CC[C@H](N)CC1.O=C=Nc1cccnc1>>O=C(Nc1cccnc1)N[C@@H]1CC[C@@H](Nc2cc(NC3CC3)c3ncc(C(=O)Nc4ccncn4)n3n2)CC1,,ClCCl,O,O=C(O)C(F)(F)F,,test
US04999350,CC(=O)Oc1c(C)c(C)c2c(c1C)CC(CC(=O)O)O2.O=C(Cl)C(=O)Cl>>CC(=O)Oc1c(C)c(C)c2c(c1C)CC(CC(=O)Cl)O2,,c1ccccc1,,,,test
US20040043987A1,COc1cccc(B(O)O)c1.COc1ccccc1-c1cccc2c1S(=O)(=O)NC(C1CCCCC1)N2>>COc1cccc(-c2cccc3c2S(=O)(=O)NC(C2CCCCC2)N3)c1,[Pd],,,,,test
US06136848,CCOC(=O)c1cccc2c(=O)cc(-c3ccc(O)cc3)oc12.ClCc1ccc2ccccc2n1>>CCOC(=O)c1cccc2c(=O)cc(-c3ccc(OCc4ccc5ccccc5n4)cc3)oc12,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130090323A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.Nc1cc(N2CCOCC2)ncc1I>>CC(C)(C)OC(=O)N1CC=C(c2cnc(N3CCOCC3)cc2N)CC1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US06723724B2,FC(F)(F)c1ccccc1CN1CCNCC1.O=CCCc1cc(-c2cccs2)no1>>FC(F)(F)c1ccccc1CN1CCN(CCCc2cc(-c3cccs3)no2)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20110124619A1,C1CCOC1.CCOC(=O)[C@@H](C)Oc1cc(NS(=O)(=O)N2CCCC2)nc(SCc2cccc(F)c2F)n1>>CCCC(C)C.CCOCC,,C1CCOC1,,[BH4-].[Li+],,test
US20100249119A1,Nc1cc(O)c(Cl)cc1F.O=[N+]([O-])c1ccc(Cl)nc1>>Nc1cc(Oc2ccc([N+](=O)[O-])cn2)c(Cl)cc1F,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US05929067,CCOC(=O)CCCC(Cc1c[nH]c2ccccc12)NC.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CCOC(=O)CCCC(Cc1c[nH]c2ccccc12)N(C)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,C1CCOC1,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US04861839,C=C1CC(=O)O1.C=CCO>>C=CCOC(=O)CC(C)=O,,C1COCCO1,,CC(=O)[O-].[Na+],,test
US05558971,COS(=O)(=O)C(F)(F)F.CSc1ccccc1>>C[S+](C)c1ccccc1.O=S(=O)([O-])C(F)(F)F,,ClCCl,,CCCCCC,,test
US20040132716A1,CCOC(=O)[C@@H](Cc1ccc(CC)c(CC)c1)NC(C)=O>>CCc1ccc(C[C@@H](N)C(=O)O)cc1CC,,Cl,,,,test
US03948937,CC(=O)OC(C)=O.COC(=O)c1ccccc1-c1cc(-c2ccc(OC)cc2)[nH]n1>>COC(=O)c1ccccc1-c1cc(-c2ccc(OC)cc2)n(C(C)=O)n1,,c1ccncc1,,,,test
US05733914,COC(=O)Cc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1>>Cn1c(=O)c(-c2c(Cl)cccc2Cl)cc2cnc(Nc3ccc(CC(=O)O)cc3)nc21,,CO,,CC(=O)O,[Na+].[OH-],test
US20040006071A1,CCN1c2ncc(CCOc3ccc(C(=O)OC)cc3C)cc2C(=O)N(C)c2cccnc21>>CCN1c2ncc(CCOc3ccc(C(=O)O)cc3C)cc2C(=O)N(C)c2cccnc21,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20130274255A1,O=C(Oc1ccccc1)c1ccc(Br)cc1.O=C1CCc2sccc21>>O=C(c1ccc(Br)cc1)C1Cc2sccc2C1=O,,C1CCOC1,O,Cl,[H-].[Na+],test
US20110207711A1,BrCc1ccccc1.Oc1cc(Br)cn2nccc12>>Brc1cc(OCc2ccccc2)c2ccnn2c1,,CCOCC,CN(C)C=O,[H-].[Na+],,test
US20130065859A1,COc1ccc2c(c1)CCC(O)O2.c1cnccn1>>COc1ccc(O)c(CCC(O)c2cnccn2)c1,,C1CCOC1,CCCCCC,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US20150329523A1,COc1cc(N)cc(S(=O)(=O)C2CC2)c1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)cc1>>COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)nn4-c4ccc(C)cc4)c4ccccc34)n2)cc(S(=O)(=O)C2CC2)c1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20080167361A1,Cc1cc(Br)ccc1C(CCOS(C)(=O)=O)CNC(=O)OC(C)(C)C>>Cc1cc(Br)ccc1C1CCN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US07091227B2,CCOC(=O)CCCNC(=O)Nc1nc2ccc(Br)cc2s1>>O=C(O)CCCNC(=O)Nc1nc2ccc(Br)cc2s1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20030187052A1,CC(=O)Nc1cccc2c1C(=O)OC2=O.CCOc1cc(C(N)CS(C)(=O)=O)ccc1OC>>CCOc1cc(C(CS(C)(=O)=O)N2C(=O)c3cccc(NC(C)=O)c3C2=O)ccc1OC,,CC(=O)O,,,,test
US20150225394A1,CC(C)(C)OC(=O)N1CC(CC#N)(N2CCC(=O)CC2)C1.N[C@@H]1C[C@H]1c1ccccc1>>CC(C)(C)OC(=O)N1CC(CC#N)(N2CCC(N[C@@H]3C[C@H]3c3ccccc3)CC2)C1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130072679A1,Brc1cncc(Br)c1.O=C1CC[C@@H](CO)N1>>O=C1CC[C@@H](CO)N1c1cncc(Br)c1,[Cu]I,C1COCCO1,,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US20120202804A1,C[C@H]1OC[C@@](NC(=O)OC(C)(C)C)(c2ccccc2F)[C@@H]1C(O)C(F)(F)F>>C[C@H]1OC[C@@](N)(c2ccccc2F)[C@@H]1C(O)C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130150359A1,COc1cc2ncc(N)c(C(=O)c3ccc(C#N)cc3)c2cc1OCc1ccccc1.O=N[O-]>>COc1cc2ncc3[nH]nc(-c4ccc(C#N)cc4)c3c2cc1OCc1ccccc1,,Cl,O,Cl[Sn]Cl,,test
US06506901B2,O=C(OO)c1cccc(Cl)c1.c1ccc2c(c1)[nH]c1cccc(OC[C@@H]3CO3)c12>>Oc1ccc2[nH]c3ccccc3c2c1OC[C@@H]1CO1,,ClCCl,,,,test
US20090291937A1,CI.N#CCc1cccc(Br)c1>>CC(C#N)c1cccc(Br)c1,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20040167131A1,CC(O)C(O)(NC(=O)OC(C)(C)C)C(=O)Nc1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1.O=C=Nc1ccc(Cl)cc1>>CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C(CO)(CO)NC(=O)Nc2ccc(Cl)cc2)cc1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20090247757A1,O=S(=O)(Oc1ccc2ccccc2c1C1N[C@@H](c2ccccc2)Cc2ccccc21)C(F)(F)F>>O=S(=O)(Oc1ccc2ccccc2c1C1=N[C@@H](c2ccccc2)Cc2ccccc21)C(F)(F)F,,ClCCl,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20130184460A1,Cn1cnc(C(=O)N(CC(=O)ON=C(N)c2ccc(OC(F)(F)F)cc2)C2CCC2)c1>>Cn1cnc(C(=O)N(Cc2nc(-c3ccc(OC(F)(F)F)cc3)no2)C2CCC2)c1,,CN(C)C=O,,CC(=O)O,,test
US05360811,CC#CO[Si](C)(C)C.CCCCCCCCCCCCC[N+](=O)[O-].O=C=Nc1ccccc1>>CCCCCCCCCCCCc1cc(CO)on1,,c1ccccc1,,CCN(CC)CC,,test
US05089485,CCCCCCCCCCCCC(N)c1coc([Si](C)(C)C)c1.CS(=O)(=O)Cl>>CCCCCCCCCCCCC(NS(C)(=O)=O)c1coc([Si](C)(C)C)c1,,ClCCl,,CCN(CC)CC,,test
US20030220361A1,CC(C)(C)OC(=O)N1CCC(N)CC1.O=C(O)c1cc(F)cnc1Cl>>CC(C)(C)OC(=O)N1CCC(NC(=O)c2cc(F)cnc2Cl)CC1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20100093694A1,CC(C)Oc1cc2c(C(=O)O)c(-c3ccc(F)cc3)oc2cc1NS(C)(=O)=O.N>>CC(C)Oc1cc2c(C(N)=O)c(-c3ccc(F)cc3)oc2cc1NS(C)(=O)=O,,CCOC(C)=O,CN(C)C=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20040209921A1,Cc1ccc(S(=O)(=O)n2cnc(CCN(Cc3ncc(C)cc3C)Cc3ncccc3C(C)(C)c3ccc(F)cc3)c2)cc1>>Cc1cnc(CN(CCc2c[nH]cn2)Cc2ncccc2C(C)(C)c2ccc(F)cc2)c(C)c1,,CO,,On1nnc2ccccc21,,test
US20140142114A1,Clc1ccc2c(c1)CC(CN1CCNCC1)O2.O=C(Cl)CCl>>O=C(CCl)N1CCN(CC2Cc3cc(Cl)ccc3O2)CC1,,ClCCl,,CCN(CC)CC,,test
US20100324041A1,CC(C)(C)OC(=O)NCCC(=O)N1CCN(c2c(-c3ccccc3)cnc3[nH]cc(NC(=O)c4cccnc4)c23)CC1>>NCCC(=O)N1CCN(c2c(-c3ccccc3)cnc3[nH]cc(NC(=O)c4cccnc4)c23)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120270838A1,Cc1cc(N(CCO)C(=O)CBr)cc(C)c1Br>>Cc1cc(N2CCOCC2=O)cc(C)c1Br,,CC(C)(C)O,,O,CC(C)(C)[O-].[K+],test
US20140018319A1,COc1ccc(CCl)cc1.CSc1nc(Nc2nc(C)n(C)n2)c2ncc(C#N)n2n1>>COc1ccc(CN(c2nc(C)n(C)n2)c2nc(SC)nn3c(C#N)cnc23)cc1,,CN(C)C=O,,[H-].[Na+],,test
US06258833B1,COc1ccc(C=O)cc1O.OC1Cc2ccccc2C1>>COc1ccc(C=O)cc1OC1Cc2ccccc2C1,,C1CCOC1,CCOCC,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120022080A1,CC(C)(C)OC(=O)Nc1ccc(C23CC4CC(CC(C4)C2)C3)cc1>>Nc1ccc(C23CC4CC(CC(C4)C2)C3)cc1,,CCOC(C)=O,,Cl,,test
US20150133511A1,C#Cc1ccc(Br)cc1.CCOC(=O)Cl>>CCOC(=O)C#Cc1ccc(Br)cc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20150376611A1,CC(C)[Si](Cl)(O[Si](Cl)(C(C)C)C(C)C)C(C)C.OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O>>CC(C)[Si]1(C(C)C)OC[C@H]2O[C@@H](n3cnc4c(Cl)ncnc43)[C@H](O)[C@@H]2O[Si](C(C)C)(C(C)C)O1,,c1ccncc1,,O,,test
US05138090,CC(=O)OCc1cc(COC(C)=O)c(C(C)C)cc1C(C)C>>CC(C)c1cc(C(C)C)c(CO)cc1CO,,CO,,[K+].[OH-],,test
US20050143579A1,CC(C)(C)OC(=O)N1CCN(CCc2ccccn2)CC1.O=C1CCCCC1>>CC(C)(C)OC(=O)N1CCN(CC(c2ccccn2)C2(O)CCCCC2)CC1,,C1CCOC1,,[Li]CCCC,,test
US06368814B1,CN(C)CCCC1c2ccccc2CCc2cc(OCCCC(=O)O)ccc21.O=C1CCC(=O)N1O>>CN(C)CCCC1c2ccccc2CCc2cc(OCCCC(=O)ON3C(=O)CCC3=O)ccc21,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20080103141A1,CC(C)(C)OC(=O)N1CCC(COc2ncc(-c3ccc(S(C)(=O)=O)cc3)cn2)CC1.O=C(Cl)OCc1ccccc1>>CS(=O)(=O)c1ccc(-c2cnc(OCC3CCN(C(=O)OCc4ccccc4)CC3)nc2)cc1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20050222213A1,C[O-].O=[N+]([O-])c1ccc(F)c(C(F)(F)F)c1>>COc1ccc([N+](=O)[O-])cc1C(F)(F)F,,C1CCOC1,,CCOC(C)=O,O,test
US04863948,CNCC(Cc1ccccc1)n1ncc2ccccc2c1=O.Cl>>CNCCn1ncc2ccccc2c1=O.Cl,[Pd],CCO,,,,test
US20020193367A1,CC(C)(C)OC(=O)Nc1cc(Cl)c(Cl)cc1[N+](=O)[O-].CCNC>>CCN(C)c1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1Cl,,CS(C)=O,,,,test
US20070082912A1,CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2c(F)cc(F)cc2F)c1>>Cc1ccc(-c2cc(Br)ccc2OCc2c(F)cc(F)cc2F)n1-c1cccc(C(=O)O)c1,,CCO,,[Na+].[OH-],,test
US20100280070A1,CC(=O)c1ccccc1N.N#Cc1ccc(C=O)cc1>>N#Cc1ccc(C=CC(=O)c2ccccc2N)cc1,,CCO,,[Na+].[OH-],,test
US20040220186A1,CC(C)c1[nH]nc(C(N)=O)c1NC(=O)C[C@@H]1CCCC[C@H]1N=[N+]=[N-]>>CC(C)c1n[nH]c2c(=O)[nH]c(C[C@@H]3CCCC[C@H]3N=[N+]=[N-])nc12,,CC(C)O,,CC(C)(C)[O-].[K+],,test
US20140309222A1,COc1ccc(N=C=O)cc1.Cc1sc2nc(N)nc(N3CCNCC3)c2c1-c1ccccc1>>COc1ccc(NC(=O)N2CCN(c3nc(N)nc4sc(C)c(-c5ccccc5)c34)CC2)cc1,,CC#N,ClCCl,,,test
US20070213300A1,COC(=O)Cc1ccc(OP(=O)(OCc2ccccc2)OCc2ccccc2)cc1>>O=C(O)Cc1ccc(OP(=O)(OCc2ccccc2)OCc2ccccc2)cc1,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US04618607,CC(=O)CC(=O)OC(CN1CCCCC1)c1ccccc1.COC(=O)/C=C(/C)N.O=Cc1cccc([N+](=O)[O-])c1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OC(CN2CCCCC2)c2ccccc2)C1c1cccc([N+](=O)[O-])c1,,CC(C)O,,,,test
US20120101039A1,II.Oc1ccccc1F>>Oc1ccc(I)cc1F,,CO,O,CCOC(C)=O,[Na+].[OH-],test
US05889012,Brc1ccc(OCc2ccccc2)cc1.COC(=O)C(F)(F)F>>O=C(c1ccc(OCc2ccccc2)cc1)C(F)(F)F,,C1CCOC1,Cc1ccccc1,Cl,[Li]CCCC,test
US20110015240A1,CC(=O)Nc1nc(COc2ccc(CCOC(=O)NNC(=O)OC(C)(C)C)cc2)cs1>>CC(=O)Nc1nc(COc2ccc(CCOC(=O)NN)cc2)cs1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140142085A1,N#Cc1cccc(-c2cccnc2[C@H](Cc2cc(F)cc(Cl)c2)NC(=O)Cc2c[nH]c3ccc(O)cc23)c1.OO>>NC(=O)c1cccc(-c2cccnc2[C@H](Cc2cc(F)cc(Cl)c2)NC(=O)Cc2c[nH]c3ccc(O)cc23)c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130289033A1,NCCc1c[nH]c2ccc(Cl)cc12.O=C(Cl)c1ccccc1I>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccccc1I,,ClCCl,,CCN(CC)CC,Cl,test
US20100249085A1,C1N2CN3CN1CN(C2)C3.Cc1ccc(Cn2nc(-c3nc(-c4ccc(NC(=O)CBr)cc4)no3)cc2C)cc1>>Cc1ccc(Cn2nc(-c3nc(-c4ccc(N5CNCC5=O)cc4)no3)cc2C)cc1,,CCO,,CCOC(C)=O,O=C([O-])O.[Na+],test
US20100256376A1,CN1CCN(Cc2ccc([N+](=O)[O-])c(Cl)c2)CC1.COC(=O)c1sc(N)cc1O[C@H](C)c1ccccc1C(F)(F)F>>COC(=O)c1sc(Nc2cc(CN3CCN(C)CC3)ccc2[N+](=O)[O-])cc1O[C@H](C)c1ccccc1C(F)(F)F,,CC(C)(C)O,,CC(C)c1cc(C(C)C)c(-c2ccccc2P(C2CCCCC2)C2CCCCC2)c(C(C)C)c1,O=C([O-])[O-].[K+].[K+],test
US04110101,CCO.CCOC(CN(C(=O)CCl)C(C)C)OCC.Cc1ccccc1S(=O)(=O)O>>CC1COC(CN(C(=O)CCl)C(C)C)OCC1C,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20120059028A1,OCCCc1c(O)cccc1Cl>>Clc1cccc2c1CCCO2,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20040082784A1,CCCC(CCC)Nc1ncnc(-c2ccc(OC)cc2Cl)c1N.CCOC(=O)C(C)=O>>CCCC(CCC)n1c(=O)c(C)nc2c(-c3ccc(OC)cc3Cl)ncnc21,,CCO,,,,test
US20140275172A1,FC(F)(F)c1cccc(Cl)n1.II>>FC(F)(F)c1nc(Cl)ccc1I,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20160200716A1,COC(=O)[C@H](CCN1CCOCC1)NC(=O)N(C)Cc1csc(C(C)C)n1.O=C(O)C(=O)O>>COC(=O)[C@H](CCN1CCOCC1)NC(=O)N(C)Cc1csc(C(C)C)n1.O=C(O)C(=O)O,,CC(=O)CC(C)C,,,,test
US20050209253A1,Cc1cc(Br)cc(C)c1NC(=O)C(C)Br.N#CCC#N>>Cc1cc(Br)cc(C)c1N1C(=O)C(C)C(C#N)=C1N,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20050038101A1,CCOC(=O)c1cc2cc(NC(=O)CC(C)(C)C)ccc2n1-c1ccccc1>>CC(C)(C)CC(=O)Nc1ccc2c(c1)cc(C(=O)O)n2-c1ccccc1,,C1CCOC1,CO,[Li+].[OH-],,test
US20070161653A1,C#C[Mg]Br.O=Cc1c(-c2ccco2)nn2c(Cl)cccc12>>C#CC(O)c1c(-c2ccco2)nn2c(Cl)cccc12,,C1CCOC1,,O,,test
US20080009524A1,CC(C)(C)OC(=O)Nc1cccc(Br)c1.N#Cc1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)Nc1cccc(-c2ccc(C#N)cc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20140349998A1,COc1ncccc1B(O)O.Ic1c[nH]c2ncnc(-c3ccccc3)c12>>COc1ncccc1-c1c[nH]c2ncnc(-c3ccccc3)c12,[Pd],C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090186879A1,NC(=O)c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl>>N#Cc1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl,,CN(C)C=O,,O=S(Cl)Cl,O=C([O-])O.[Na+],test
US20040224948A1,CCOC(=O)CC(Sc1ccc2c(c1)OCC(=O)N2CCCN(C(=O)OCc1ccccc1)c1ccccn1)c1ccccc1>>CCOC(=O)CC(Sc1ccc2c(c1)OCC(=O)N2CCCNc1ccccn1)c1ccccc1,,CC(=O)O,,Br,,test
US20140275065A1,Cc1ccc(N(C)C)c(C(N)=O)n1.[OH-]>>Cc1ccc(N(C)C)c(C(=O)O)n1,,CCO,,Cl,,test
US20120149899A1,CCCCI.CCN1C(=O)C(C)C(=O)N(C)c2cc(OCc3ccccc3)ccc21>>CCCCC1(C)C(=O)N(C)c2cc(OCc3ccccc3)ccc2N(CC)C1=O,,CCOC(C)=O,,CN(C)C=O,[H-].[Na+],test
US20110118245A1,CC(C)(C(=O)O)C(F)(F)F.C[Si](C)(C)C=[N+]=[N-]>>COC(=O)C(C)(C)C(F)(F)F,,CCOCC,ClCCl,,,test
US20110076292A1,CC(C)(C)OC(=O)N1C2CCC1C(=O)NC2>>O=C1NCC2CCC1N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070099986A1,O=C(CCCCCl)c1ccc2c(c1)CCO2.O=[N+]([O-])O>>O=C(CCCCCl)c1cc2c(c([N+](=O)[O-])c1)OCC2,,CCOC(C)=O,,O=S(=O)(O)O,,test
US20070142431A1,[N-]=[N+]=NC(c1ccccc1F)C1CC1>>NC(c1ccccc1F)C1CC1,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090318467A1,C1CCN(C2CCNCC2)C1.Cc1cc(-c2cccc(C(F)(F)F)c2)cnc1C(=O)O>>Cc1cc(-c2cccc(C(F)(F)F)c2)cnc1C(=O)N1CCC(N2CCCC2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060241148A1,COC(=O)Cc1nc(Cl)c(F)cc1C#N>>N#Cc1cc(F)c(Cl)nc1CC(=O)O,,C1COCCO1,,Cl,,test
US20110034451A1,CCCO.Cc1c(Cl)nn2c(N)nnc2c1C>>CCCOc1nn2c(N)nnc2c(C)c1C,,CN(C)C=O,,[H-].[Na+],,test
US06228859B1,COc1ccc(CO)cc1OCc1ccccc1.O=S(Cl)Cl>>COc1ccc(CCl)cc1OCc1ccccc1,,ClCCl,,,,test
US20090137561A1,CC(C)(C)[Si](C)(C)Oc1cc(F)cc(C=O)c1F.CC[Mg]Br>>CCC(O)c1cc(F)cc(O[Si](C)(C)C(C)(C)C)c1F,,C1CCOC1,,,,test
US04241058,CC(=CN1CCCCC1)Cc1ccc(C(C)(C)C)cc1>>CC(Cc1ccc(C(C)(C)C)cc1)CN1CCCCC1,[Pd],Cc1ccccc1,,[H][H],,test
US07351858B2,CCNCc1ccccc1F.COC(=O)c1ccccc1OCCc1ccc(OCC(=O)O)cc1>>CCN(Cc1ccccc1F)C(=O)COc1ccc(CCOc2ccccc2C(=O)OC)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20130059833A1,COC(=O)c1nc(C)n(C)c1C(=O)OC>>COC(=O)c1nc(C)n(C)c1C(=O)O,,C1CCOC1,CO,[Li+].[OH-],,test
US20110251181A1,C[C@@H]1C[C@@H](OC(=O)c2ccc([N+](=O)[O-])cc2)c2ncnc(-c3ccc4c(C(CNC(=O)OC(C)(C)C)c5ccc(Cl)cc5)nsc4c3)c21>>C[C@@H]1C[C@@H](O)c2ncnc(-c3ccc4c(C(CNC(=O)OC(C)(C)C)c5ccc(Cl)cc5)nsc4c3)c21,,C1CCOC1,,[Li+].[OH-],,test
US03944675,NCc1ccccc1.O=C(Cl)C12CC3CC(CC(C3)C1)C2>>O=C(NCc1ccccc1)C12CC3CC(CC(C3)C1)C2,,CCOCC,,,,test
US05420151,C=CCNC1COc2cccc(OC)c2C1.CCCI>>C=CCN(CCC)C1COc2cccc(OC)c2C1,,CCOCC,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20140051672A1,CN(c1ccc(-c2cc3ccc(O)cc3cc2OCc2ccccc2)nn1)C1CC(C)(C)NC(C)(C)C1.O=C1CCC(=O)N1Br>>CN(c1ccc(-c2cc3ccc(O)c(Br)c3cc2OCc2ccccc2)nn1)C1CC(C)(C)NC(C)(C)C1,,CN(C)C=O,,,,test
US20030083315A1,CCOC(=O)CCCBr.Fc1cc2nc(S)[nH]c2cc1F>>CCOC(=O)CCCSc1nc2cc(F)c(F)cc2[nH]1,,CN(C)C=O,,CCN(CC)CC,O,test
US20090048203A1,ClC1CCCC1.Nc1nc(SCc2ccccc2)nc2[nH]cnc12>>Nc1nc(SCc2ccccc2)nc2c1ncn2C1CCCC1,,CN(C)C=O,O,[H-].[Na+],,test
US20100022518A1,COC(=O)C(CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)N1CCN(c2cccc(OC(F)(F)F)c2)C(C)C1=O>>COC(=O)C(CCO)N1CCN(c2cccc(OC(F)(F)F)c2)C(C)C1=O,,ClCCl,,ClB(Cl)Cl,,test
US20020010199A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)OC(C)(C)C.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OS(=O)(=O)C(F)(F)F)cc1)C(=O)OC(C)(C)C,,ClCCl,,c1ccncc1,,test
US20160102071A1,CC#C[C@@H](CC(=O)OCC)c1ccc(COc2ccc3scc(-c4ccc(OC5CCOCC5)cc4C)c3c2)cc1>>CC#C[C@@H](CC(=O)O)c1ccc(COc2ccc3scc(-c4ccc(OC5CCOCC5)cc4C)c3c2)cc1,,CCO,,Cl,[Li+].[OH-],test
US20160039794A1,CN1CCN(C2CCNCC2)CC1.CS(=O)(=O)OCc1ccc([N+](=O)[O-])c([N+](=O)[O-])c1>>CN1CCN(C2CCN(Cc3ccc([N+](=O)[O-])c([N+](=O)[O-])c3)CC2)CC1,,ClCCl,,CCN(CC)CC,,test
US04775692,C=[N+]=[N-].O=C(O)C1CCCCC1>>COC(=O)C1CCCCC1,,CCOCC,,,,test
US20050222410A1,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1cnc(N2CCN(Cc3ccccc3)CC2)cn1>>Nc1ccccc1NC(=O)c1cnc(N2CCN(Cc3ccccc3)CC2)cn1,,C1COCCO1,CCOCC,Cl,,test
US04007202,C=C(C)C(C(=O)OCc1ccc([N+](=O)[O-])cc1)N1C(=O)C(NC(=O)COc2ccccc2)C1SN1C(=O)c2ccccc2C1=O.O=C1CCC(=O)N1Br>>C=C(CBr)C(C(=O)OCc1ccc([N+](=O)[O-])cc1)N1C(=O)C(NC(=O)COc2ccccc2)C1SN1C(=O)c2ccccc2C1=O,,ClCCCl,,,,test
US20120046285A1,CNC(=O)c1ccc(CCC(=O)OC(C)(C)C)nc1.Cl>>CNC(=O)c1ccc(CCC(=O)O)nc1.Cl,,C1COCCO1,,,,test
US05389653,COc1cc(C(=O)Cl)cc([N+](=O)[O-])c1OC.Cn1ccnc1>>COc1cc(C(=O)c2nccn2C)cc([N+](=O)[O-])c1OC,,c1ccncc1,,CCN(CC)CC,[Na+].[OH-],test
US20120295915A1,O=C(Cl)C1CC1.O=[N+]([O-])c1cc(Cl)cnc1NC[C@@H]1CCNC1>>O=C(C1CC1)N1CC[C@@H](CNc2ncc(Cl)cc2[N+](=O)[O-])C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100240706A1,CCCCn1ccc(-c2ccc(C3(COC4CCCCO4)CCOCC3)cc2)c(Cl)c1=O>>CCCCn1ccc(-c2ccc(C3(CO)CCOCC3)cc2)c(Cl)c1=O,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100137281A1,CCc1cc2c(=O)[nH]c(=O)n(Cc3ccc(-c4ccccc4C#N)cc3)c2s1.COc1ccc(C(=O)CBr)cc1OC>>CCc1cc2c(=O)n(CC(=O)c3ccc(OC)c(OC)c3)c(=O)n(Cc3ccc(-c4ccccc4C#N)cc3)c2s1,,CCOC(C)=O,,CN(C)C=O,[H-].[Na+],test
US20070167433A1,COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CC(O)C3c3ccc(OCCCOc4ccccc4Cl)cc3)cc21>>COCCCN1CCOc2ccc(COC3CNCC(O)C3c3ccc(OCCCOc4ccccc4Cl)cc3)cc21,,C1COCCO1,O,CO,[K+].[OH-],test
US04699914,C=C(C)C(N)=O.CC(=O)Cc1ccc(-n2ccnc2)cc1>>CC1=C(c2ccc(-n3ccnc3)cc2)CC(C)C(=O)N1,,C1COCCO1,,CC(C)(C)[O-].[K+],,test
US20130085127A1,COC(=O)c1ccc(CCl)o1.c1ccc(C(OC2CCNCC2)c2ccccc2)cc1>>COC(=O)c1ccc(CN2CCC(OC(c3ccccc3)c3ccccc3)CC2)o1,,CCOC(C)=O,O,CC#N,O=C([O-])[O-].[K+].[K+],test
US05576324,C=CCc1cc(C)c2[nH]c(=O)ccc2c1O.O=C1CCC(=O)N1Br>>Cc1cc2c(c3ccc(=O)[nH]c13)OC(CBr)C2,,ClC(Cl)Cl,,CCCCCC,,test
US20100317643A1,CN(C)C=O.Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1.O=C(O)c1ccc(Br)s1>>O=C(Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1)c1cnc(Br)s1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04024156,O=C=O.c1ccc(-c2cccs2)cc1>>O=C(O)c1ccc(-c2ccccc2)s1,,C1CCOC1,CCCCCC,CCOCC,[Li]CCCC,test
US20140249133A1,COc1cnc(-c2nn(Cc3ccccc3F)c3ccccc23)nc1Nc1ccncc1C#N.OO>>COc1cnc(-c2nn(Cc3ccccc3F)c3ccccc23)nc1Nc1ccncc1C(N)=O,,CS(C)=O,,[Na+].[OH-],,test
US20100160303A1,BrCc1ccccc1.O=C1NCCN1>>O=C1NCCN1Cc1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US20020037915A1,CSc1sc(N=CNC(=O)OC(C)(C)C)cc1-c1csc(Nc2ccc(O)cc2)n1.NC(=O)CBr>>CSc1sc(N=CNC(=O)OC(C)(C)C)cc1-c1csc(Nc2cccc(OCC(N)=O)c2)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020025960A1,COC(=O)c1ccc2sccc2c1O.NCc1ccc(Cl)cc1>>O=C(NCc1ccc(Cl)cc1)c1ccc2sccc2c1O,,CCOC(C)=O,CO,,,test
US05919748,CC(C)O.CCCCCCCCCCCCOCC1CO1.Cl.N=C(N)NCCC[C@H](N)C(=O)O>>CCCCCCCCCC(OCCCN[C@@H](CCCNC(=N)N)C(=O)O)C(C)O.Cl,,O,,,,test
US20090209607A1,CCn1ncc(Cl)c1-c1csc(C(=O)OC)c1>>CCn1ncc(Cl)c1-c1csc(C(=O)O)c1,,C1CCOC1,O,[K+].[OH-],,test
US20090312310A1,CS(=O)(=O)O[C@@H]1CN(Cc2ccccc2)C[C@H]1OS(C)(=O)=O.O=C(Cl)OCc1ccccc1>>CS(=O)(=O)O[C@@H]1CN(C(=O)OCc2ccccc2)C[C@H]1OS(C)(=O)=O,,ClCCl,,,,test
US20110251181A1,C[C@@H]1C[C@@H](O)c2ncnc(-c3ccc4c(C(CNC(=O)OC(C)(C)C)c5ccc(Cl)cc5)nsc4c3)c21.Cl.ClCCl>>C[C@@H]1C[C@@H](O)c2ncnc(-c3ccc4c(C(CN)c5ccc(Cl)cc5)nsc4c3)c21.Cl.Cl.Cl,,C1COCCO1,ClCCl,,,test
US20150361125A1,CI.COCO[C@H]1CC[C@@]2(C)[C@@H]3CC[C@@]4(C)C[C@H](O)C[C@@H]4[C@H]3CC[C@@H]2C1>>COCO[C@H]1CC[C@@]2(C)[C@@H]3CC[C@@]4(C)C[C@H](OC)C[C@@H]4[C@H]3CC[C@@H]2C1,,C1CCOC1,,,,test
US20150329548A1,C[C@@H]1CC[C@@H](Cn2ccc3nc(Cl)nc(Cl)c32)CC1.O=Cc1ccccc1F>>C[C@@H]1CC[C@@H](Cn2c(C(O)c3ccccc3F)cc3nc(Cl)nc(Cl)c32)CC1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20160214997A1,CCOC(=O)CC(C)(C)N.ClCC1CO1>>CCOC(=O)CC(C)(C)N1CC(O)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20030045558A1,CCOC(=O)C(C)(C)Oc1ccc(OCCc2nc(-c3cccc(-c4ccccc4)c3)oc2C)cc1CC1CCCCC1>>Cc1oc(-c2cccc(-c3ccccc3)c2)nc1CCOc1ccc(OC(C)(C)C(=O)O)c(CC2CCCCC2)c1,,CCO,,[Na+].[OH-],,test
US06380239B1,NC(=O)C[C@H](N)C(=O)O.O=C1OC(=O)c2c1cccc2[N+](=O)[O-]>>NC(=O)CC(C(=O)O)N1C(=O)c2cccc([N+](=O)[O-])c2C1=O,,CC(=O)O,,,,test
US20130045169A1,O=C(NC(c1ccccc1)c1cc(Br)cc(OCCCCCCCCC2OCCO2)c1)O[C@H]1CN2CCC1CC2.OB(O)c1ccccc1>>O=C(NC(c1ccccc1)c1cc(OCCCCCCCCC2OCCO2)cc(-c2ccccc2)c1)O[C@H]1CN2CCC1CC2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20010039333A1,CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O.CS(=O)(=O)O>>CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O.CS(=O)(=O)[O-],,CC(C)=O,,,,test
US05241064,C=C(C(=O)[O-])C(C)O[Si](C)(C)C(C)(C)C.COc1ccc(CN)cc1>>COc1ccc(CN2C[C@@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)C2=O)cc1,,CO,,,,test
US20110230458A1,CCCCc1nnc(OC2CCN(C)CC2)cc1-c1ccc(OCc2ccccc2)cc1>>CCCCc1nnc(OC2CCN(C)CC2)cc1-c1ccc(O)cc1,[Pd],CCOC(C)=O,CO,,,test
US20060173020A1,Nc1nc(Nc2ccc(S(N)(=O)=O)cc2)nn1C(=O)c1c(F)cccc1F.O=C1CCCC(=O)O1>>Nc1nc(Nc2ccc(S(=O)(=O)NC(=O)CCCC(=O)O)cc2)nn1C(=O)c1c(F)cccc1F,CC(=O)O,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20100298315A1,C1COCCN1.Clc1ccc2nnc(Cl)n2n1>>Clc1nnc2ccc(N3CCOCC3)nn12,,CN(C)C=O,,CCN(CC)CC,O,test
US03996352,CCOc1cc([N+](=O)[O-])cc(N)n1.O=C(Cl)CCl>>CCOc1cc([N+](=O)[O-])cc(NC(=O)CCl)n1,,CCOCC,,c1ccncc1,,test
US20060100262A1,COC(=O)CCn1c(Br)c(C2CCCCC2)c2ccc(C(=O)OC)cc21.O=Cc1ccccc1B(O)O>>COC(=O)CCn1c(-c2ccccc2C=O)c(C2CCCCC2)c2ccc(C(=O)OC)cc21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20140011795A1,CC1(C)[C@H](NC(=O)OCc2ccccc2)CC[C@@]1(C)O>>CC1(C)[C@H](N)CC[C@@]1(C)O,[Pd],CO,,,,test
US20070213331A1,CC(=O)N1[C@@H](Cc2cc(F)cc(F)c2)[C@@H]([C@H]2C[C@H](O)CN2C(=O)OC(C)(C)C)OC1(C)C.COc1ccccc1O>>COc1ccccc1O[C@@H]1C[C@H]([C@H]2OC(C)(C)N(C(C)=O)[C@H]2Cc2cc(F)cc(F)c2)N(C(=O)OC(C)(C)C)C1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04431647,CSCOc1cccc2c1CC(NC(C)=O)C2=O>>CCN[C@@H]1Cc2c(OCSC)cccc2[C@H]1O,,C1CCOC1,,[H-].[Na+],,test
US20090131458A1,CC1(C)CC(C=CCCOCc2ccccc2)CCO1>>CC1(C)CC(CCCCO)CCO1,[Pd],CCOC(C)=O,,,,test
US20070123504A1,COC1CCN(c2ccc([N+](=O)[O-])cn2)C1>>COC1CCN(c2ccc(N)cn2)C1,[Pd],CCOC(C)=O,,,,test
US05246952,CC1(C)c2ccccc2S(=O)(=O)N1F.N#Cc1ccc2c(c1)CCCC2c1ccns1>>N#Cc1ccc2c(c1)CCCC2(F)c1ccns1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US05166397,CC(=O)N(CC(=O)O)c1ccccc1.NC1CC(CO)C1CO>>CC(=O)N(CC(=O)O)c1ccccc1.N[C@@H]1C[C@H](CO)[C@H]1CO,,CO,,,,test
US05861421,CC(=O)OC(C)=O.COc1ccc(C2(C#Cc3cccc(N)c3)CCC(=O)CC2)cc1OC1CCCC1>>COc1ccc(C2(C#Cc3cccc(NC(C)=O)c3)CCC(=O)CC2)cc1OC1CCCC1,c1ccncc1,ClCCl,,Cl,,test
US20120157425A1,CC(=O)N[C@@H](C)c1ccc(C2CCN(C#N)CC2)cc1.NO>>CC(=O)N[C@@H](C)c1ccc(C2CCN(C(=N)NO)CC2)cc1,,CCO,,CCN(C(C)C)C(C)C,Cl,test
US20080039504A1,COC(OC)OC.NNC(=O)c1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1.Nc1cn[nH]c1>>O=S(=O)(Nc1cc(Cl)cnc1-c1nncn1-c1cn[nH]c1)c1ccc(Cl)c(C(F)(F)F)c1,,CC(=O)O,,CC#N,,test
US20040038993A1,COC(=O)Cc1ccc(OCc2ccccc2)cc1.COC(N(C)C)N(C)C>>COC(=O)C(=CN(C)C)c1ccc(OCc2ccccc2)cc1,,Cc1ccccc1,,,,test
US20020111369A1,COCCCl.O=C(O)c1ccc(O)cc1>>COCCOc1ccc(C(=O)O)cc1,,CCO,O,Cl,[K+].[OH-],test
US06143764,CC(C)c1ccccc1N=C=O.COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccccc4C(C)C)cc3)c2cc1OC,,Cc1ccccc1,,,,test
US20120202785A1,C[C@H](N)c1nc2ccccc2n1C1CCCOC1.Clc1ncnc2c1ncn2C1CCCCO1>>C[C@H](Nc1ncnc2[nH]cnc12)c1nc2ccccc2n1C1CCCOC1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20040058978A1,CCOC(=C1C(=O)N(C(C)=O)c2ccc([N+](=O)[O-])cc21)c1ccccc1.CS(=O)(=O)N(CCN1CCOCC1)c1ccc(N)cc1>>CS(=O)(=O)N(CCN1CCOCC1)c1ccc(N/C(=C2\C(=O)Nc3ccc([N+](=O)[O-])cc32)c2ccccc2)cc1,,CN(C)C=O,CO,C1CCNCC1,,test
US20100029949A1,CCOC(=O)CBr.Cc1cc2c(CCc3cc(-c4ccc(C(F)(F)F)cc4)nn3C(C)C)noc2cc1O>>CCOC(=O)COc1cc2onc(CCc3cc(-c4ccc(C(F)(F)F)cc4)nn3C(C)C)c2cc1C,,CC(C)=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20140112945A1,COc1ccc(C2=NN(C3CCN(C(=O)[C@H](Cc4ccccc4Cl)NC(=O)OC(C)(C)C)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](N)Cc4ccccc4Cl)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC,,C1COCCO1,Cl,,,test
US20080009530A1,CCOC(=O)/C=C/c1ccc(OCCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1Oc1ncc(C(F)(F)F)cc1Cl>>CC(C)(C)[Si](OCCOc1ccc(/C=C/C(=O)O)c(Oc2ncc(C(F)(F)F)cc2Cl)c1)(c1ccccc1)c1ccccc1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20020064681A1,Brc1ccc2c(c1)CCCC2.[O-]B([O-])[O-]>>OB(O)c1ccc2c(c1)CCCC2,,C1CCOC1,CCCCCC,Cl,O,test
US05064861,O=C(O)COc1ccc(Cl)cc1Cl.O=S(Cl)Cl>>O=C(Cl)COc1ccc(Cl)cc1Cl,,c1ccccc1,,,,test
US05916889,C1CNCCN1.N#Cc1ccccc1F>>N#Cc1ccccc1N1CCNCC1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US04036984,CC(=O)Cl.OCCSc1ccccc1>>CC(=O)OCCSc1ccccc1,,c1ccncc1,,,,test
US20140094462A1,C=CC[C@@H](CC(=O)OC(C)(C)C)C(=O)O.CN[C@H](C)[C@H](O)c1ccccc1>>C=CC[C@@H](CC(=O)OC(C)(C)C)C(=O)N(C)[C@H](C)[C@H](O)c1ccccc1,,ClCCl,,,,test
US05998433,C=O.CNC.c1ccc(CC2Cc3occc3CN2)cc1>>CN(C)Cc1cc2c(o1)CC(Cc1ccccc1)NC2,,CC(=O)O,,,,test
US20090137561A1,CCCCOc1cc(C(=O)O)ccc1Br>>CCCCOc1cc(CO)ccc1Br,,C1CCOC1,,,,test
US05889178,CCNC(=O)[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O.Nc1ccccc1O>>CCNC(=O)[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(Nc4ccccc4O)nc32)[C@H](O)[C@@H]1O,,CS(C)=O,,C1CCC2=NCCCN2CC1,,test
US20090082358A1,FC(F)(F)c1ccc(C2NCCc3cnccc32)cc1.O=C=Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)N1CCc2cnccc2C1c1ccc(C(F)(F)F)cc1,,ClCCCl,,,,test
US20130178540A1,CCCCCCCCCCNC(=O)C(CCS(C)=O)OC(C)=O>>CCCCCCCCCCNC(=O)C(O)CCS(C)=O,,CO,ClCCl,[Na+].[OH-],,test
US20060041128A1,CC(C)(C)OC(=O)NCC=O.Cc1nsc2nc(C(N)C(C)C)n(Cc3ccccc3)c(=O)c12>>Cc1nsc2nc(C(NCCNC(=O)OC(C)(C)C)C(C)C)n(Cc3ccccc3)c(=O)c12,CC(=O)O,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070203229A1,CC(=O)Nc1ccc(OC(C)=O)cc1OC[C@@H]1CO1.NC1CCC2(CC1)Cc1cc(Cl)ccc1O2>>CC(=O)Nc1ccc(O)cc1OC[C@@H](O)CNC1CCC2(CC1)Cc1cc(Cl)ccc1O2,,CCO,,,,test
US20080221180A1,CC(=O)Nc1nc(C)c(-c2cc(S(=O)(=O)Cl)sc2Br)s1.CN1CCC(N)CC1>>CC(=O)Nc1nc(C)c(-c2cc(S(=O)(=O)NC3CCN(C)CC3)sc2Br)s1,,ClCCl,,CCN(CC)CC,,test
US20020099212A1,CCOC(C)(OCC)OCC.Nc1ccc(Br)nc1N>>Cc1nc2nc(Br)ccc2[nH]1,,CC(=O)O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20130005744A1,BrCc1ccccc1.O=c1[nH]cc(-c2cccc(-c3ccccc3)c2)c(F)c1O>>O=c1[nH]cc(-c2cccc(-c3ccccc3)c2)c(F)c1OCc1ccccc1,,CO,,[Na+].[OH-],,test
US20150072980A1,COc1cc2c(cc1N1CCOCC1)CCC2=O.O=Cc1cc(C(F)(F)F)ccc1Cl>>COc1cc2c(cc1N1CCOCC1)C/C(=C\c1cc(C(F)(F)F)ccc1Cl)C2=O,,CCOC(C)=O,Cc1ccccc1,Cc1ccc(S(=O)(=O)O)cc1,,test
US20030032645A1,CC(C)(C)OC(=O)N1C2CCC1CC(O)(c1ccc3ccccc3c1)C2>>C1=C(c2ccc3ccccc3c2)CC2CCC1N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US04014916,CC(=O)OCCN1C(=O)CN2CCOC2(c2ccccc2F)c2cc(Cl)ccc21>>O=C1CN2CCOC2(c2ccccc2F)c2cc(Cl)ccc2N1CCO,,CO,,O,[Na+].[OH-],test
US20080214553A1,COc1cccc(-c2nc3ccc(OC[C@@H](C)CO)cc3c(=O)n2CC(=O)NC(C)C)c1.CS(=O)(=O)Cl>>COc1cccc(-c2nc3ccc(OC[C@@H](C)COS(C)(=O)=O)cc3c(=O)n2CC(=O)NC(C)C)c1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20150210687A1,COc1cc(-c2nn(Cc3c(Cl)cccc3C3CC3)c3cccc(F)c23)c(F)cc1C(=O)O>>O=C(O)c1cc(F)c(-c2nn(Cc3c(Cl)cccc3C3CC3)c3cccc(F)c23)cc1O,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20060241115A1,COc1cc2ncc(C#N)c(Cl)c2cc1OC.O=C(O)c1cccc2cc(O)ccc12>>COc1cc2ncc(C#N)c(Oc3ccc4c(C(=O)O)cccc4c3)c2cc1OC,,CN(C)C=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04616011,ClCCCBr.O=C1Cc2ccccc2CC(=O)N1>>O=C1Cc2ccccc2CC(=O)N1CCCCl,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20090099176A1,CC(C)(C)[Si](C)(C)OCCN1C(=O)C(NC(=O)c2cc3cc(Cl)ncc3[nH]2)Cc2ncccc21>>O=C(NC1Cc2ncccc2N(CCO)C1=O)c1cc2cc(Cl)ncc2[nH]1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140135316A1,CC(=O)NN.Fc1cccc2c1NC(=S)CCN2>>Cc1nnc2n1-c1c(F)cccc1NCC2,,CCCCO,,,,test
US20050288273A1,COC(=O)CCC#Cc1cccc([N+](=O)[O-])c1F>>COC(=O)CCCCc1cccc([N+](=O)[O-])c1F,[Pd],CO,,,,test
US20050153902A1,CCOC(=O)CC(NC(=O)C(COCc1ccccc1)NC(=O)OCCNc1cccc(C)n1)c1cc(Cl)cc(Cl)c1>>Cc1cccc(NCCOC(=O)NC(COCc2ccccc2)C(=O)NC(CC(=O)O)c2cc(Cl)cc(Cl)c2)n1,,CC(=O)O,,CCO,[Na+].[OH-],test
US20080194650A1,COc1c(C)cccc1Cl.O=C1CCC(=O)N1Br>>COc1c(Cl)cccc1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20090156612A1,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C[C@H]1CCO.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C[C@H]1CCOS(C)(=O)=O,,C1CCOC1,,CCN(CC)CC,O,test
US20060004046A1,CC(C)(C)Sc1c(C#N)cnc2ccc(C=O)cc12.COc1ccc(/C=C2\SC(=N)NC2=O)cc1OC1CCCC1>>CC(C)(C)Sc1c(C#N)cnc2ccc(/C=C3\SC(N)=NC3=O)cc12,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20130053382A1,CC(C)(C)OC(=O)NCc1ccc(-c2cc(F)ccc2[N+](=O)[O-])cc1>>CC(C)(C)OC(=O)NCc1ccc(-c2cc(F)ccc2N)cc1,[Pd],CCOC(C)=O,,,,test
US04703106,C[C@@H](OCc1ccccc1)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1>>C[C@@H](OCc1ccccc1)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N1CCC[C@H]1C(=O)O,,C1CCOC1,,Cl,[Na+].[OH-],test
US20110306587A1,Clc1cc(Cl)c(Cl)nn1.OCC1CCNCC1>>OCC1CCN(c2cc(Cl)nnc2Cl)CC1,,CS(C)=O,O,CCN(CC)CC,,test
US20120059034A1,O=C(Nc1ccc2[nH]c(=O)oc2c1)C(=O)N1CCC(Cc2ccc(F)cc2)CC1>>O=C(Nc1ccc2[nH]c(=O)oc2c1)C(=O)N1CCC(Cc2ccc(F)cc2)CC1,,CC(C)=O,O,,,test
US20160137584A1,BrCCCCBr.CC(C)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)C(C)(C)CCCCBr,,C1CCOC1,CCOC(C)=O,O,CC(C)[N-]C(C)C.[Li+],test
US05147863,N#CCl.c1ccc(Cn2ccnc2)cc1>>N#Cc1nccn1Cc1ccccc1,,CC#N,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20040235822A1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(C(O)c4cccc[n+]4[O-])c(Cl)c2)CCN3C(=O)C(F)(F)F)cc1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(C(O)c4cccc[n+]4[O-])c(Cl)c2)CCN3)cc1,,CCO,,[BH4-].[Na+],,test
US20100249124A1,CCN1C(=O)COc2ccc(C(O)(C(C)c3ccc(OS(=O)(=O)C(F)(F)F)cc3Cl)C(F)(F)F)cc21.COC(=O)c1ccc(B(O)O)cc1Cl>>CCN1C(=O)COc2ccc(C(O)(C(C)c3ccc(-c4ccc(C(=O)OC)c(Cl)c4)cc3Cl)C(F)(F)F)cc21,,C1COCCO1,CCOC(C)=O,O,O=C([O-])[O-].[Na+].[Na+],test
US20150210666A1,COC(=O)CCCCCCN.C[Si](C)(C)CCOC(=O)ON1C(=O)CCC1=O>>COC(=O)CCCCCCNC(=O)OCC[Si](C)(C)C,,ClCCl,,CCN(CC)CC,Cl,test
US20040157904A1,Cc1cccc(C)c1N.Cl.O=N[O-]>>Cc1cccc(C)c1NN.Cl,,Cl,O,Cl[Sn]Cl,,test
US20100256156A1,CCOCc1oc(-c2ccc(C(F)(F)F)cc2)cc1C(O)C1CCCCC1.O=C(Cl)C(=O)Cl>>CCOCc1oc(-c2ccc(C(F)(F)F)cc2)cc1C(Cl)C1CCCCC1,,C1CCOC1,,CCN(CC)CC,O,test
US20050208582A1,Fc1cccc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3ccncc23)c1>>Fc1cccc(-c2n[nH]c3ccncc23)c1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20110311474A1,Cc1ccc(S(=O)(=O)n2ccc3c2ncc2nnc(C[C@@H]4CCNC4)n23)cc1.N#Cc1cnc(Cl)cn1>>Cc1ccc(S(=O)(=O)n2ccc3c2ncc2nnc(C[C@@H]4CCN(c5cnc(C#N)cn5)C4)n23)cc1,,CCCO,,CCN(C(C)C)C(C)C,ClCCl,test
US20120308920A1,C=C(C)C(=O)OC1C2CC3C1OC(=O)C3C2C(=O)O.O=C(Cl)C(=O)Cl>>C=C(C)C(=O)OC1C2CC3C1OC(=O)C3C2C(=O)Cl,,Cc1ccccc1,,,,test
US20150218144A1,COc1cccc(C(=O)CBr)c1.NCc1ccccc1>>COc1cccc(C(O)CNCc2ccccc2)c1,,ClC(Cl)Cl,,CCO,[BH4-].[Na+],test
US20030176449A1,Cc1ccn2c(-c3cccc(B4OC(C)(C)C(C)(C)O4)c3)cnc2n1.Cc1nc(-c2cccc(Br)c2)no1>>Cc1ccn2c(-c3cccc(-c4cccc(-c5noc(C)n5)c4)c3)cnc2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US05459137,CC1=NN=C(c2ccc(N)cc2)c2cc3c(cc2C1)OCO3.O=C(Cl)c1ccccc1>>CC1=NN=C(c2ccc(NC(=O)c3ccccc3)cc2)c2cc3c(cc2C1)OCO3,,ClCCl,,CCN(CC)CC,CCO,test
US20140113882A1,COc1cncc2nc(-c3ccncc3)nc(N3CCC(NC(=O)OC(C)(C)C)(C(=O)N[C@@H](CCO)c4ccc(Cl)cc4)CC3)c12>>COc1cncc2nc(-c3ccncc3)nc(N3CCC(N)(C(=O)N[C@@H](CCO)c4ccc(Cl)cc4)CC3)c12,,CS(C)=O,ClCCl,O=C(O)C(F)(F)F,,test
US20100324030A1,O=[N+]([O-])c1cc(C2OCCCO2)ccc1O>>Nc1cc(C2OCCCO2)ccc1O,[Ni],C1CCOC1,,,,test
US20060199817A1,COC(=O)c1ccc(C)c(-c2ccc3c(C#N)nncc3c2)c1.NC1CC1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(C#N)nncc2c1,,CCOC(C)=O,CN(C)C=O,Cl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050245503A1,CN1CC[C@@H](NC(=O)c2cnc(Cl)c(Cl)c2)C1=O.NN>>CN1CC[C@@H](NC(=O)c2cnc(NN)c(Cl)c2)C1=O,,CCO,,,,test
US20090131444A1,CC(C)(C)OC(=O)OC(C)(C)C.COC(=O)[C@@H]1CCC(=O)N1>>COC(=O)[C@@H]1CCC(=O)N1C(=O)OC(C)(C)C,CN(C)c1ccccn1,CCN(CC)CC,ClCCl,,,test
US20080262050A1,NO.O=C(Cl)c1cc([N+](=O)[O-])c(O)cc1O>>O=C(NO)c1cc([N+](=O)[O-])c(O)cc1O,,C1COCCO1,,O,,test
US04263324,CCCCCCCCCCCC(C)=O.ONCl>>CCCCCCCCCCCC(C)=NO,,CCO,O,[Na+].[OH-],,test
US20090099169A1,C#CC(C)C.COC(=O)c1cc(C#N)cc(I)c1O>>COC(=O)c1cc(C#N)cc2cc(C(C)C)oc12,[Cu]I,CN(C)C=O,O,,,test
US20150073019A1,COC(OC)N(C)C.O=c1cc(-c2cc3ccccc3s2)[nH]n1-c1nc2ccccc2s1>>CN(C)C=C1C(=O)N(c2nc3ccccc3s2)N=C1c1cc2ccccc2s1,,C1CCOC1,,,,test
US05106871,CO.COCOc1cc(OCOC)c(C(C)=O)c(O)c1CC=C(C)C>>COCOc1ccc(C=O)cc1,,CO,,,,test
US20020183337A1,CC(C)Cn1c(=O)n(C)c(=O)c2c(Sc3cccc(N)c3)c(Cc3cccc4ccccc34)sc21.CCN(CC)CC.COC(=O)Cl>>CCCC(C)C.COC(=O)Nc1cccc(Sc2c(Cc3cccc4ccccc34)sc3c2c(=O)n(C)c(=O)n3CC(C)C)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US05665719,CC(C)(C)ON1CCC(O)CC1.CCOC(=O)/N=N/C(=O)OCC.COC(=O)c1ccc(O)cc1O>>COC(=O)c1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1O,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20120214803A1,COc1cc(NS(=O)(=O)c2ccc(C)cc2[N+](=O)[O-])c2ncccc2c1>>COc1cc(NS(=O)(=O)c2ccc(C)cc2N)c2ncccc2c1,[Ni],,,NN,O,test
US04058539,CC(=O)OC(C)=O.C[C@]12CC[C@H]3C(=C1CC[C@@H]2O)C=CC1=C[C@@H](O)CC[C@@]13CO.c1ccncc1>>CC(=O)OC[C@]12CC[C@H](OC(C)=O)C=C1C=CC1=C3CC[C@H](OC(C)=O)[C@@]3(C)CC[C@@H]12,,c1ccncc1,,,,test
US05134154,CCOC(=O)C(Br)c1ccccc1.COc1ccccc1O>>CCOC(=O)C(Oc1ccccc1OC)c1ccccc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140343029A1,CCc1c(N)ncnc1Cl.Cl.FC(F)(F)c1cc(-c2cn(CCN3CCC3)c(C3CCNCC3)n2)ccn1>>CCc1c(N)ncnc1N1CCC(c2nc(-c3cccc(Cl)n3)cn2CCN2CCC2)CC1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050020616A1,COC(=O)C(C)(C)Br.N#CCc1ccccc1>>COC(=O)C(C)(C)C(C#N)c1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20090275571A1,CN(C(=O)CN1C(=O)COc2cc(Cl)c(Cl)cc21)C(CN1CCOCC1)c1ccc(-c2cccc(N(C(=O)[O-])C(C)(C)C)c2)cc1>>CN(C(=O)CN1C(=O)COc2cc(Cl)c(Cl)cc21)C(CN1CCOCC1)c1ccc(-c2cccc(N)c2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060293519A1,COCCOc1nc(C)cc(OCC(F)(F)F)c1[N+](=O)[O-]>>COCCOc1nc(C)cc(OCC(F)(F)F)c1N,[Ni],C1COCCO1,CO,[H][H],,test
US20040014940A1,CC(C)C(=O)O.CC(C)CC(CNC(=O)OC(C)Cl)CC(=O)OCc1ccccc1>>CC(C)CC(CNC(=O)OC(C)OC(=O)C(C)C)CC(=O)OCc1ccccc1,,ClCCl,,CN1CCOCC1,,test
US05128350,CO/C=C(/C(=O)OC)c1c(OCc2ccccc2)c(C)nn1C>>CO/C=C(/C(=O)OC)c1c(O)c(C)nn1C,[Pd],CO,,,,test
US20120157448A1,C=CC1(O)c2cc(Br)ccc2O[C@H]2CCCC[C@@H]21.NC(N)=S>>N=C(N)SC/C=C1/c2cc(Br)ccc2OC2CCCCC12,,ClCCl,,O=S(Cl)Cl,,test
US20100144695A1,CC(C)(C)OC(=O)NCC(=O)O.COc1ccc(C2(O)CCC(N3CC(N)C3)CC2)cn1.O=C(O)C(F)(F)F.On1nnc2ccccc21>>COc1ccc(C2(O)CCC(N3CC(NC(=O)CNC(=O)c4ccc(C(F)(F)F)cc4)C3)CC2)cn1,,ClCCl,,CCN=C=NCCCN(C)C,,test
US04346088,CCN(CC)c1ccc(N=c2scc(-c3ccc(Cl)c(S(=O)(=O)N(C)C)c3)n2C)cc1>>CCN(CC)c1ccc(N=c2scc(-c3ccc(Cl)c(S(=O)(=O)N(C)C)c3)n2C)cc1,,CO,,Br,CCN(CC)CC,test
US04133809,CC(C)(C)OC(=O)NN.CSC1=Nc2ccc(Cl)cc2N(c2ccccc2)C(=O)C1>>CC(C)(C)OC(=O)NNC1=Nc2ccc(Cl)cc2N(c2ccccc2)C(=O)C1,,CN(C)C=O,,,,test
US20020128306A1,CC(C)[C@H](NC(=O)c1cc2cc(F)ccc2n1C)C(=O)NC(CC(=O)OC(C)(C)C)C(O)CF.O=C(Cl)C(=O)Cl>>CC(C)[C@H](NC(=O)c1c(Cl)c2cc(F)ccc2n1C)C(=O)NC(CC(=O)OC(C)(C)C)C(=O)CF,,CS(C)=O,,ClCCl,,test
US20160207905A1,Clc1ncc(Cl)c(Cl)n1.Nc1cc([N+](=O)[O-])ccc1F>>O=[N+]([O-])c1ccc(F)c(Nc2nc(Cl)ncc2Cl)c1,,C1CCOC1,,[H-].[Na+],,test
US20100331346A1,COC(=O)CC(NS(=O)C(C)(C)C)c1ccccc1.Cl>>COC(=O)CC(N)c1ccccc1.Cl,,C1COCCO1,CO,,,test
US20030220324A1,CC(C)(C)OC(=O)N[C@H](Cc1ccc(Cl)c(Cl)c1)C(=O)N1CCN(c2ccccc2NS(C)(=O)=O)CC1>>CS(=O)(=O)Nc1ccccc1N1CCN(C(=O)[C@H](N)Cc2ccc(Cl)c(Cl)c2)CC1,,CCOC(C)=O,,,,test
US20080255192A1,Cc1ccc2c(c1)NC(=O)C2=O.Cc1cccc2c1C(=O)C(=O)N2>>Cc1ccc2c(c1)NC(=O)C2=O.Cc1cccc2c1C(=O)C(=O)N2,,O=S(=O)(O)O,,,,test
US20040260047A1,CCCCCCCCCC(Br)Br.c1ccc2c(c1)[nH]c1ccccc12>>BrCCCCCCCCCCn1c2ccccc2c2ccccc21,,C1CCOC1,,[H-].[Na+],,test
US20030083374A1,O=C(O)CCC(CCCSC(c1ccccc1)(c1ccccc1)c1ccccc1)(C(=O)O)C(=O)O>>O=C(O)CCC(CCCSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O,,CS(C)=O,,,,test
US20130203768A1,C1CNCCN1.CNC(=O)c1c(Cl)cc(C)nc1C>>CNC(=O)c1c(N2CCNCC2)cc(C)nc1C,,c1ccncc1,,,,test
US20020198197A1,CCOc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2ccnc(C#N)c2)cc1C(F)(F)F>>CCOc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1ccnc(C#N)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050137224A1,CC(C)(C)OC(=O)N1[C@H]2CC[C@H]([C@H](O)C2)[C@H]1C(=O)N1CCC[C@H]1C#N.Cl>>Cl.N#C[C@@H]1CCCN1C(=O)[C@H]1N[C@H]2CC[C@@H]1[C@H](O)C2,,C1COCCO1,,,,test
US20120289501A1,O=C1CC(c2ccccc2)Oc2cc(Br)ccc21>>OC1CC(c2ccccc2)Oc2cc(Br)ccc21,,CO,,[BH4-].[Na+],,test
US20080312226A1,CC(=O)Nc1ccc(NC(=O)OCC(Cl)(Cl)Cl)cn1.Fc1ccccc1-c1csc(N2CCNCC2)n1>>CC(=O)Nc1ccc(NC(=O)N2CCN(c3nc(-c4ccccc4F)cs3)CC2)cn1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20150119405A1,COc1cc(OC)c(Cl)c(-c2ccc3nc(Cl)ncc3c2)c1Cl.C[Si](C)(C)CCOC(=O)N[C@H]1C[C@@H]2C[C@@H]2[C@H]1N>>COc1cc(OC)c(Cl)c(-c2ccc3nc(N[C@@H]4[C@H]5C[C@H]5C[C@@H]4NC(=O)OCC[Si](C)(C)C)ncc3c2)c1Cl,,CCOC(C)=O,CN1CCCC1=O,O=C([O-])O.[Na+],,test
US20160168090A1,COC(=O)c1cn(CCO)c2cccc(Cl)c12.O=C(O)C(F)(F)S(=O)(=O)F>>COC(=O)c1cn(CCOC(F)F)c2cccc(Cl)c12,[Cu]I,,,,,test
US03984562,O=C(Oc1ccc2c(c1)CN1CCCC1CN2C(=O)CCN1CCCC1)c1ccccc1>>O=C(CCN1CCCC1)N1CC2CCCN2Cc2cc(O)ccc21,[Pd],CCO,,[H][H],,test
US06310056B1,C=Cc1ncn2ccsc12>>CCc1ncn2ccsc12,[Pd],CCO,O,[H][H],,test
US05116941,CC(C)(C)OC(=O)CC[C@@H](NC(=O)OCc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)O>>CC(C)(C)OC(=O)CC[C@@H](N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)O,[Pd],CO,,,,test
US20150291595A1,CN(C)S(=O)(=O)Cl.COc1cc(N)ccc1-c1cn(COCC[Si](C)(C)C)c2ncnc(N[C@@H](C)c3nn4ccc(C)c4c(=O)n3-c3ccccc3)c12>>COc1cc(NS(=O)(=O)N(C)C)ccc1-c1cn(COCC[Si](C)(C)C)c2ncnc(N[C@@H](C)c3nn4ccc(C)c4c(=O)n3-c3ccccc3)c12,,C1CCOC1,,c1ccncc1,,test
US20100075948A1,CC(C)(C)[Si](C)(C)OCC(=O)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)[Si](C)(C)OCC(=O)c1ccc(N)cc1,[Zn],CO,,[Cl-].[NH4+],,test
US20090105250A1,CCN1CCN(c2cc(C(=O)Nc3ccc(C)c(N)c3)cc(C(F)(F)F)c2)CC1.O=C(O)c1cnc(Br)s1>>CCN1CCN(c2cc(C(=O)Nc3ccc(C)c(NC(=O)c4cnc(Br)s4)c3)cc(C(F)(F)F)c2)CC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05075299,BrC(c1ccccc1)c1ccccc1.COc1ccc(COc2cn(O)c(CO)c(C)c2=O)cc1>>COc1ccc(COc2c(C)n(OC(c3ccccc3)c3ccccc3)c(CO)cc2=O)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06613850B1,COc1c(C(C)(C)C)cc(C)cc1[Si](C)(C)Cl.[Li]C1C(C)=C(C)C(C)=C1C>>COc1c(C(C)(C)C)cc(C)cc1[Si](C)(C)C1(C)C=C(C)C(C)=C1C,,C1CCOC1,,,,test
US06002008,COc1cc2ncc(C#N)c(Cl)c2cc1OC.Nc1ccc(Oc2ccccc2)cc1>>COc1cc2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c2cc1OC,,CCOCCO,,Cl,c1ccncc1,test
US20130217664A1,CCc1cc(-c2cnc(N3CCOCC3)nc2)ccc1Nc1cc2c(cn1)ncn2C.CI>>CCc1cc(-c2cnc(N3CCOCC3)nc2)ccc1N(C)c1cc2c(cn1)ncn2C,,CN(C)C=O,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20130237501A1,C=C[Mg]Br.CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(c3ccc(C=O)c(Cl)c3)S(C)(=O)=O)c(C3CC3)cc12>>C=CC(O)c1ccc(N(c2cc3oc(-c4ccc(F)cc4)c(C(=O)NC)c3cc2C2CC2)S(C)(=O)=O)cc1Cl,,C1CCOC1,,[Cl-].[NH4+],,test
US20030125334A1,CC(C)(C)OC(=O)N1CCN(c2nc(OCc3cccc(Cl)c3)cnc2Cl)CC1.Cl>>Cl.Clc1cccc(COc2cnc(Cl)c(N3CCNCC3)n2)c1,,C1COCCO1,,CCOCC,,test
US05004739,O=C(O)c1cc2ccc(Br)cc2c2ccccc12>>OCc1cc2ccc(Br)cc2c2ccccc12,,C1CCOC1,,B,,test
US20140088121A1,CS(=O)(=O)NCCCBr.Nc1ncnc2[nH]c(Sc3cc4c(cc3I)OCO4)nc12>>CS(=O)(=O)NCCCn1c(Sc2cc3c(cc2I)OCO3)nc2c(N)ncnc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150141465A1,CCn1nccc1N(C(=O)COc1cccc(OCOC)c1C=O)C(C)C>>CCn1nccc1N(C(=O)COc1cccc(O)c1C=O)C(C)C,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20110160243A1,CC(C)Oc1ccc(COc2ccc3c(c2)cc2n3CCC2CC(=O)O)cc1C(F)(F)F.O=C1CCC(=O)N1Cl>>CC(C)Oc1ccc(COc2ccc3c(c2)c(Cl)c2n3CCC2CC(=O)O)cc1C(F)(F)F,,ClCCl,,,,test
US05866583,N#Cc1ccc(C2=NCCc3ccccc32)cc1>>N#Cc1ccc(C2NCCc3ccccc32)cc1,,CO,O,[BH4-].[Na+],,test
US20120277217A1,Nc1ccccc1-c1cnc[nH]1.O=Cc1ccccc1>>C(=N/c1ccccc1-c1cnc[nH]1)\c1ccccc1,,CC(=O)O,CCOC(C)=O,,,test
US20110039889A1,CC(C)(C)OC(=O)CCc1nccc2c(-c3noc(-c4ccc(F)c(C#N)c4)n3)cccc12.FC1CCNC1>>CC(C)(C)OC(=O)CCc1nccc2c(-c3noc(-c4ccc(N5CCC(F)C5)c(C#N)c4)n3)cccc12,,CN(C)C=O,,[H-].[Na+],,test
US20040132727A1,CC(O)c1cc(F)c(F)cc1F.COc1cc2nccc(Oc3cc(C)c(N)cc3C)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3cc(C)c(NC(=O)OC(C)c4cc(F)c(F)cc4F)cc3C)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20060160800A1,CN(C)C=O.Fc1cc(Br)ccc1-c1ccccc1>>O=Cc1ccc(-c2ccccc2)c(F)c1,,C1CCOC1,C1CCOC1,[Li]CCCC,,test
US20150239889A1,CC(C)(C)[Si](C)(C)O[C@H]1CC[C@@H](CO)CC1.CCOC(=O)c1cnn(-c2nc(OC)c3[nH]ncc3n2)c1>>CCOC(=O)c1cnn(-c2nc(OC)c3c(cnn3C[C@@H]3CC[C@H](O[Si](C)(C)C(C)(C)C)CC3)n2)c1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05563143,BrC1CCCC1.COc1ccc(-n2cnc3cnccc32)cc1O>>COc1ccc(-n2cnc3cnccc32)cc1OC1CCCC1,,CN(C)C=O,,O,[H-].[Na+],test
US06197759B1,CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COC(c1ccccc1)(c1ccccc1)c1ccccc1)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>CCCCCCCC/C=C\CCCCCCCC(=O)OCC(CO)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140329794A1,CC(C)(C)OC(=O)N(Cc1cccc(C(=O)NCC(O)CN2CCc3ccccc3C2)c1)C1CCOCC1>>O=C(NCC(O)CN1CCc2ccccc2C1)c1cccc(CNC2CCOCC2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04734415,NCCBr.O=C1CCC(c2ccc(N=C=S)cc2)=NN1>>O=C1CCC(c2ccc(NC3=NCCS3)cc2)=NN1,,CN(C)C=O,,Br,O=C([O-])[O-].[K+].[K+],test
US04277394,CC(=O)OC(C)=O.NNC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1>>CC(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1,,C1CCOC1,,,,test
US20030004162A1,CC(=O)c1ccc2c(c1)CC(=O)N2CC(F)(F)F.OCCO>>CC1(c2ccc3c(c2)CC(=O)N3CC(F)(F)F)OCCO1,,CCOC(C)=O,c1ccccc1,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080242661A1,CCCc1nn(C)c(C(N)=O)c1N.O=C(n1ccnc1)n1ccnc1>>CCCc1nn(C)c2c(=O)[nH]c(=O)[nH]c12,,CC#N,,,,test
US20090264434A1,COC(=O)C(CC1CCCC1)n1ncc(Oc2ccccc2C(C)=O)cc1=O>>CC(=O)c1ccccc1Oc1cnn(C(CC2CCCC2)C(=O)O)c(=O)c1,,C1COCCO1,Cl,,,test
US20140206606A1,COC(=O)c1ccc(C=O)cc1[N+](=O)[O-].NO>>COC(=O)C1=C([N+](=O)[O-])CC(=NO)C=C1,,CC(C)O,O,Cl,CC(=O)[O-].[Na+],test
US20110015230A1,CCCCNc1cc(F)ccc1C(=O)N(C)OC.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCNc1cc(F)ccc1C=CC(=O)OC,,C1CCOC1,Cc1ccccc1,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110230461A1,COC(=O)C1(CCl)CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(CO)(CCl)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110275611A1,CNc1nc(Cl)cc(N2C[C@@H](C(=O)NCc3ccccc3)CC[C@H]2C)n1.N#Cc1c(F)cc(B(O)O)cc1F>>CNc1nc(-c2cc(F)c(C#N)c(F)c2)cc(N2C[C@@H](C(=O)NCc3ccccc3)CC[C@H]2C)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])O.[Na+],,test
US20100075948A1,CCN(C(C)C)C(C)C.ClCCl.N#CC1(c2ccc(Cl)cc2F)C(CC2(CO)CC=CCC2)NC(C(=O)O)C1c1cccc(Cl)c1F.O=C(O)C(F)(F)F>>CC1(C)OC[C@H](CCNC(=O)C2NC(CC3(CO)CC=CCC3)C(C#N)(c3ccc(Cl)cc3F)C2c2cccc(Cl)c2F)O1,,ClCCl,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20100035918A1,Cc1cccc(NC(=O)NC(C)C(O[Si](C)(C)C(C)(C)C)c2ccc3ncnn3c2)c1>>Cc1cccc(NC(=O)NC(C)C(O)c2ccc3ncnn3c2)c1,,O,,CCO,Cl,test
US04342692,COc1ccc(CC[N+](=O)[O-])cc1OC.O=C(CCI)CCc1ccc(F)cc1>>COc1ccc(CC(CCC(=O)CCc2ccc(F)cc2)[N+](=O)[O-])cc1OC,,C1CCOC1,,,,test
US20120223276A1,O=S(=O)(c1ccccc1)n1c2ccc(-n3c4ccccc4c4cc(-c5ccccc5)ccc43)cc2c2cc(-n3c4ccccc4c4cc(-c5ccccc5)ccc43)ccc21>>c1ccc(-c2ccc3c(c2)c2ccccc2n3-c2ccc3[nH]c4ccc(-n5c6ccccc6c6cc(-c7ccccc7)ccc65)cc4c3c2)cc1,,CS(C)=O,O,Cl,[K+].[OH-],test
US20060052599A1,CC(C)(C)OC(=O)N1CC[C@@H](Nc2ccc(/C=C/C(=O)O)cn2)C1.CCN=C=NCCCN(C)C.CCOC(C)=O.CN(C)C=O.On1nnc2ccccc21>>CC(C)(C)OC(=O)N1CC[C@@H](Nc2ccc(/C=C/C(=O)NOC3CCCCO3)cn2)C1,,CN(C)C=O,,O,,test
US20130046004A1,COC(=O)c1cc(OCC2CC2)n(-c2ccccc2F)n1>>O=C(O)c1cc(OCC2CC2)n(-c2ccccc2F)n1,,CO,,[Na+].[OH-],,test
US05492905,COc1cc(=O)c2ccc(Cl)cc2[nH]c1=O.ClI>>COc1c(I)c(=O)c2ccc(Cl)cc2[nH]c1=O,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20020016460A1,CC1(C)c2ccc3nc(Nc4c(Cl)cccc4Cl)[nH]c3c2C(=O)NC1O>>Cc1[nH]c(=O)c2c(ccc3nc(Nc4c(Cl)cccc4Cl)[nH]c32)c1C,,O=S(=O)(O)O,,O=C([O-])O.[Na+],,test
US20080300216A1,N#Cc1ccc(C(Cl)(c2ccccc2)c2ccccc2)cc1.NC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C[C@@H]1O>>N#Cc1ccc(C(NC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)C[C@@H]2O)(c2ccccc2)c2ccccc2)cc1,,c1ccncc1,,,,test
US20040186160A1,O=C1Cc2cc(Cl)ccc2N1.O=Cc1[nH]c2c(c1CCCO)CCCCC2>>O=C1Nc2ccc(Cl)cc2/C1=C/c1[nH]c2c(c1CCCO)CCCCC2,,CCO,,C1CCNCC1,,test
US20070265278A1,COc1ccc(NN)cc1.O=C(O)CCC(=O)c1ccc(Cl)c(S(=O)(=O)NC2CCCCC2)c1>>COc1ccc2[nH]c(-c3ccc(Cl)c(S(=O)(=O)NC4CCCCC4)c3)c(CC(=O)O)c2c1.N,,O,,Cl,[K+].[OH-],test
US20120095002A1,COC(=O)C#CC(=O)OC.ON=C(Cl)c1ccc(C(F)(F)F)c(F)c1>>COC(=O)c1onc(-c2ccc(C(F)(F)F)c(F)c2)c1C(=O)OC,,Cc1ccccc1,,CCN(CC)CC,,test
US20070066583A1,COc1cc(N2CCN(C(=O)CCl)CC2)ccc1Cl.Cn1c(=O)[nH]c2cc(Cl)ccc21>>COc1cc(N2CCN(C(=O)Cn3c(=O)n(C)c4ccc(Cl)cc43)CC2)ccc1Cl,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20080085886A1,O=C1c2ccccc2C(=O)N1O.OC1COC(c2ccccc2)OC1>>O=C1c2ccccc2C(=O)N1OC1COC(c2ccccc2)OC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100331293A1,CN(C)C1CCNC1.Cc1c(-c2ccc(F)nc2)nc2cc(F)cc(F)c2c1Cl>>Cc1c(-c2ccc(N3CCC(N(C)C)C3)nc2)nc2cc(F)cc(F)c2c1Cl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080146566A1,Cc1ccc(C(=O)NC2CC2)cc1-n1ccc2ccc(O)cc2c1=O.ClCCBr>>Cc1ccc(C(=O)NC2CC2)cc1-n1ccc2ccc(OCCCl)cc2c1=O,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20080121870A1,C1COCCO1.CCCCCCCCCCCCOc1ccc(C=O)cc1OCCCCCCCCCCCC>>C=Cc1ccc(OCCCCCCCCCCCC)c(OCCCCCCCCCCCC)c1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20070225296A1,C[C@H](c1cccc2ccccc12)N(C(=O)Cl)[C@@H]1CCCN(C(=O)OCc2ccccc2)C1>>C[C@@H](N[C@@H]1CCCN(C(=O)OCc2ccccc2)C1)c1cccc2ccccc12,,C1CCOC1,,O,,test
US20120028919A1,CSc1ncc2cc3ccccc3n2n1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1ncc2cc3ccccc3n2n1,,ClCCl,O,O=C([O-])O.[Na+],,test
US20050014727A1,CCOP(=O)(CC#N)OCC.COc1cc(OC)cc(C(=O)c2ccc3c(c2)OCCO3)c1>>COc1cc(OC)cc(C(=CC#N)c2ccc3c(c2)OCCO3)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20100168418A1,Cc1cc(=O)n(CCN2CCC(N(Cc3ccc4c(c3)OCCO4)C(=O)OC(C)(C)C)CC2)c2cc(C3CCCCC3)ccc12.Cl>>Cc1cc(=O)n(CCN2CCC(NCc3ccc4c(c3)OCCO4)CC2)c2cc(C3CCCCC3)ccc12.Cl,,CCOC(C)=O,,CO,,test
US20080064715A1,O=C(c1ccccc1)c1cc2cc(N(Cc3ccccc3)Cc3ccccc3)ncc2[nH]1>>Nc1cc2cc(C(O)c3ccccc3)[nH]c2cn1,[Pd],CCO,CO,O=C[O-].[NH4+],,test
US20100317659A1,COc1cc(C(=O)c2nc(Nc3cc(C)[nH]n3)c3ccccc3n2)ccc1F>>Cc1cc(Nc2nc(C(=O)c3ccc(F)c(O)c3)nc3ccccc23)n[nH]1,,ClCCl,,BrB(Br)Br,O,test
US20080287478A1,CC(C)[C@H]1CC[C@@H](N2CCC3(CC2)C(=O)N(CCCCCCCCCBr)CN3c2ccccc2)CC1.CNC.O=C(O)C(F)(F)F>>CC(C)[C@@H]1CC[C@H](N2CCC3(CC2)C(=O)N(CCCCCCCCCN(C)C)CN3c2ccccc2)CC1.O=C(O)C(F)(F)F,,CCO,,,,test
US20110275801A1,CCOC(=O)[C@@H]1CC[C@@H](c2nc(C)c(Cl)s2)CC1>>Cc1nc([C@@H]2CC[C@@H](C(=O)O)CC2)sc1Cl,,C1COCCO1,,[Na+].[OH-],,test
US05446189,CCCCCCCCCCCCCCCCCCOc1cc(OCCCOc2ccc(S(C)=O)cc2)cc(N(CC(=O)OC)CC(=O)OC)c1>>CCCCCCCCCCCCCCCCCCOc1cc(NCC(=O)O)cc(OCCCOc2ccc(S(C)=O)cc2)c1,,CO,,[Na+].[OH-],,test
US20060258690A1,COC(=O)C(C(=O)OC)c1cc(OC)ccc1[N+](=O)[O-]>>COC(=O)C1C(=O)Nc2ccc(OC)cc21,[Pd],CO,,,,test
US20130053409A1,COc1cc(N2CC(N(C)C)C2)c([N+](=O)[O-])cc1Nc1nccc(-c2cn(C)c3ccccc23)n1>>COc1cc(N2CC(N(C)C)C2)c(N)cc1Nc1nccc(-c2cn(C)c3ccccc23)n1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20070275968A1,CC(C)(O)c1ccc(Br)nc1.CI>>COC(C)(C)c1ccc(Br)nc1,,CN(C)C=O,,O,[H-].[Na+],test
US20120059028A1,COC(=O)CCC(C)=O.Nc1sc2c(c1C(=O)c1ccc3c(c1)OCO3)CCCC2>>COC(=O)Cc1c(C)nc2sc3c(c2c1-c1ccc2c(c1)OCO2)CCCC3,,CN(C)C=O,,C[Si](C)(C)Cl,,test
US20140128424A1,CCCC[C@H](C=O)NC(=O)c1c(C)nc2c(OCc3c(F)cccc3F)cccn12.C[Si](C)(C)C(F)(F)F>>CCCC[C@@H](NC(=O)c1c(C)nc2c(OCc3c(F)cccc3F)cccn12)C(O)C(F)(F)F,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120101083A1,Cc1cc2c(cc1-c1noc(-c3ccc(OC(C)C)c(C#N)c3)n1)CCNCC2.O=C(Br)CBr>>Cc1cc2c(cc1-c1noc(-c3ccc(OC(C)C)c(C#N)c3)n1)CCN(C(=O)CBr)CC2,,ClCCl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20110086834A1,CNCCO.COC(=O)C1(c2ccc(Br)cc2[N+](=O)[O-])CO1>>COC(=O)C(O)(CN(C)CCO)c1ccc(Br)cc1[N+](=O)[O-],,C1CCOC1,,,,test
US20140213586A1,COc1cncc(NC(C(=O)c2c[nH]c3c(CCOC(C)=O)cccc23)c2cncc(F)c2)c1>>COc1cncc(NC(C(=O)c2c[nH]c3c(CCO)cccc23)c2cncc(F)c2)c1,,C1CCOC1,CO,O=C([O-])[O-].[K+].[K+],,test
US20130029995A1,CC1CCN(c2nc(C(F)(F)F)ccc2CN)CC1.Nc1cnc2ccccc2c1.O=C(n1ccnc1)n1ccnc1>>CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cnc3ccccc3c2)CC1,,ClCCl,,,,test
US20080039459A1,CC(=O)n1ncc2c(Br)cccc21>>Brc1cccc2[nH]ncc12,,CO,,Cl,,test
US05576343,COc1cc(C=O)ccc1O[C@H]1CCN(C(=O)OC(C)(C)C)C1.O=CO>>COc1cc(C=O)ccc1O[C@H]1CCN(C(C)=O)C1,,ClC(Cl)Cl,ClCCl,,,test
US20010051631A1,Cl.O=C1c2cnc3cccc(n23)CN1CCCNS(=O)(=O)C(F)(F)F>>Cl.O=C1c2cnc3cccc(n23)CN1CCCNS(=O)(=O)C(F)(F)F,,CCO,,,,test
US20010047001A1,BrCC1CO1.OC1Cc2ccccc2C1>>c1ccc2c(c1)CC(OCC1CO1)C2,,CN(C)C=O,,[H-].[Na+],,test
US04863904,CCOC(=O)C(C#N)=Cc1ccccc1>>CCOC(=O)C(C#N)Cc1ccccc1,[Pd],c1ccccc1,,,,test
US04670438,C#CCBr.COc1cc(O)ccc1C1=NC2=CCNC(=O)C2=N1>>C#CCOc1ccc(C2=NC3=CCNC(=O)C3=N2)c(OC)c1,,O=S1(=O)CCCC1,,O=C([O-])[O-].[K+].[K+],,test
US04137236,CC(C)(C)OC(=O)C(C1NC(C(=O)OCc2ccccc2)C2(CCSCC2)S1)N1C(=O)c2ccccc2C1=O.Cl>>CC(C)(C)OC(=O)C(N)C1NC(C(=O)OCc2ccccc2)C2(CCSCC2)S1.Cl,,CN(C)C=O,,NN,O,test
US04032652,CC(=O)c1c(O)oc(=O)c(C(C)=O)c1O.Nc1ccc(O)cc1>>CC(=O)C1=C(O)C(=C(C)Nc2ccc(O)cc2)C(=O)OC1=O,,CO,,,,test
US05559129,C1CCOC1.CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=CC1CCCCN1C(=O)OCc1ccccc1.O=CC1CCCN1C(=O)OCc1ccccc1>>CCOC(=O)C=CC1=CCCN1C(=O)OCc1ccccc1.CCOC(=O)C=CC1CCCCN1C(=O)OCc1ccccc1,,C1CCOC1,,,,test
US20160052920A1,COc1ccc(C(Cl)(c2ccccc2)c2ccc(OC)cc2)cc1.C[C@@]1(c2nc(Cl)ccc2F)C[C@@H](C(F)(F)F)OC(N)=N1>>COc1ccc(C(NC2=N[C@](C)(c3nc(Cl)ccc3F)C[C@@H](C(F)(F)F)O2)(c2ccccc2)c2ccc(OC)cc2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20020049212A1,CC(C)(C)OC(=O)N1C2CCC1CN(c1nc3ccccc3n1C1CCN(C3(c4ccccc4)CCCCCC3)CC1)C2>>c1ccc(C2(N3CCC(n4c(N5CC6CCC(C5)N6)nc5ccccc54)CC3)CCCCCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070054916A1,CN(C)CCCN(C)c1ccc(C(F)(F)F)cc1N.CNc1ncc2cc(-c3cc(C(=O)O)ccc3C)cnc2n1>>CNc1ncc2cc(-c3cc(C(=O)Nc4cc(C(F)(F)F)ccc4N(C)CCCN(C)C)ccc3C)cnc2n1,,ClC(Cl)Cl,,O=S(Cl)Cl,O=C([O-])O.[Na+],test
US20090143372A1,CC(C)C(=O)c1cc(Br)cs1.CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(B4OC(C)(C)C(C)(C)O4)cc23)CC1>>CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4csc(C(=O)C(C)C)c4)cc23)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US05627270,O=C(OO)c1cccc(Cl)c1.c1ccc(COC[C@H]2OC(Sc3ccccc3)[C@H](OCc3ccccc3)[C@@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)cc1>>O=S(c1ccccc1)C1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,,ClCCl,,,,test
US20090156607A1,CCSC(=O)c1c(C#N)ncn1C>>Cn1cnc(C#N)c1C=O,[Pd],CC(C)=O,,CC[SiH](CC)CC,,test
US20130109661A1,BrBr.COC(=O)c1ccc(-c2ccc(N)nn2)cc1>>COC(=O)c1ccc(-c2cc(Br)c(N)nn2)cc1,,CO,,O=C([O-])O.[Na+],,test
US05929085,COC(=O)C1Cc2ccc([N+](=O)[O-])cc2CN1.O=C(Cl)CCl>>COC(=O)C1Cc2ccc([N+](=O)[O-])cc2C(C(=O)CCl)N1,,CCN(CC)CC,,ClCCl,,test
US20110144091A1,COC(CN)OC.O=C(N[C@@H]1CCc2ccccc2NC1=S)OCc1ccccc1>>COC(CNC1=Nc2ccccc2CC[C@H]1NC(=O)OCc1ccccc1)OC,Cl[Hg]Cl,C1CCOC1,,,,test
US06518265B1,CCBr.O=C(O)CC1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CC1>>CCOC(=O)CC1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CC1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20100029656A1,Cc1nc(C(F)(F)F)ccc1Cn1nc(NNC(=O)[C@H](C)OCc2ccccc2)c(-c2ccc(Cl)cc2)c(-c2ccc(C#N)cc2)c1=O>>Cc1nc(C(F)(F)F)ccc1Cn1c(=O)c(-c2ccc(C#N)cc2)c(-c2ccc(Cl)cc2)c2nnc([C@H](C)OCc3ccccc3)n21,,Cc1ccccc1,,O=P(Cl)(Cl)Cl,,test
US20060116364A1,COc1ccc([C@@H]2CCc3cc(OC(=O)C(C)(C)C)ccc3C2)c(NCCCc2ccc(CC(=O)O)cc2)c1.N>>COc1ccc([C@@H]2CCc3cc(O)ccc3C2)c(NCCCc2ccc(CCN)cc2)c1,,ClC(Cl)Cl,,,,test
US20100286148A1,O=C(OCCl)c1cc(F)cc(F)c1.O=c1nc(-c2cc(C(F)(F)F)ccn2)[nH]o1>>O=C(OCn1c(-c2cc(C(F)(F)F)ccn2)noc1=O)c1cc(F)cc(F)c1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20080319188A1,CN(C)C1CN(C2CCN(Cc3ccccc3)CC2)C1.Cl.Cl.Cl>>CN(C)C1CN(C2CCNCC2)C1.Cl.Cl.Cl,[Pd],CC(C)O,,O,,test
US20050288273A1,CCOC(=O)Cl.NC[C@H]1CN(c2ccc3c(c2)CCCc2cnoc2-3)C(=O)O1>>CCOC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCc2cnoc2-3)C(=O)O1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20120238517A1,CCN1CC(CN2C(=O)c3ccccc3C2=O)CS1(=O)=O>>CCN1CC(CN)CS1(=O)=O,,CCO,,NN,O,test
US20030232883A1,CCOC(=O)C(C)(C)C(=O)O.Nc1ccc(OCc2cccc(F)c2)cc1>>CCOC(=O)C(C)(C)C(=O)Nc1ccc(OCc2cccc(F)c2)cc1,,C1CCCCC1,CCOC(C)=O,,,test
US20150329538A1,NCc1cc(Br)c[nH]1.O=C(n1ccnc1)n1ccnc1>>O=C1NCc2cc(Br)cn21,,C1CCOC1,,[H-].[Na+],,test
US20140113882A1,COc1cncc(N)c1C(=O)O.N#Cc1ccncc1F>>COc1cncc2nc(-c3ccncc3F)nc(O)c12,,CO,,C[O-].[Na+],,test
US20040116438A1,CC(C)CC(=O)Cl.Nc1ncccc1C(=O)O>>CC(C)Cc1nc2ncccc2c(=O)o1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20080194647A1,COC(=O)c1cncc(C#Cc2ccccc2)c1.Cl>>COC(=O)c1cncc(C#Cc2ccccc2)c1.Cl,,CCOCC,,,,test
US20160244410A1,COc1ccc(Cn2c(=O)c3c(Oc4cccc(O[C@H]5CCOC5)c4C)cc(=O)n(C)c3n(-c3ccc(I)cc3F)c2=O)cc1>>COc1ccc(CNC(=O)c2c(Oc3cccc(O[C@H]4CCOC4)c3C)cc(=O)n(C)c2Nc2ccc(I)cc2F)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20100256363A1,CC1(c2ccccc2)CCN(c2cccc(Br)c2)C(=O)O1.OB(O)c1ccccc1>>CC1(c2ccccc2)CCN(c2cccc(-c3ccccc3)c2)C(=O)O1,,C1CCOC1,O,O=C([O-])O.[Na+],,test
US20130190307A1,CCOC(OCC)OCC.NNc1cnc2ccc(Br)cc2n1>>Brc1ccc2ncc3nncn3c2c1,,CCOCC,,,,test
US20100137194A1,C=CCOC(=O)c1cccc(O)c1.O=C(O)c1cc(OCc2ccccc2)c(OCc2ccccc2)c(OCc2ccccc2)c1>>C=CCOC(=O)c1cccc(OC(=O)c2cc(OCc3ccccc3)c(OCc3ccccc3)c(OCc3ccccc3)c2)c1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20100120801A1,CC(=O)c1ccccc1.O>>O=CC(=O)c1ccccc1,,C1COCCO1,,CC(=O)O,,test
US05688798,Cc1ncc(CCl)c(N)n1.Cl.c1cc2c(cn1)CCCC2>>Cc1ncc(C[n+]2ccc3c(c2)CCCC3)c(N)n1.Cl.[Cl-],,CN(C)C=O,,,,test
US20150126492A1,CC1(C=O)COC1.COC(=O)C[C@@H](N)c1ccc(C#N)cc1>>COC(=O)C[C@@H](NCC1(C)COC1)c1ccc(C#N)cc1,,CC#N,,CC(=O)O,[BH3-]C#N.[Na+],test
US20160039783A1,BrBr.Cc1ccc(F)c2c1CCCO2>>Cc1c(Br)cc(F)c2c1CCCO2,,CC(=O)O,Cc1ccccc1,,,test
US20090105258A1,CC(NC(=O)OC(C)(C)C)c1ccc(NS(C)(=O)=O)c(C#Cc2ccccc2)c1>>CC(N)c1ccc(NS(C)(=O)=O)c(C#Cc2ccccc2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070003539A1,COC(=O)c1ccccc1SCC(F)(F)F>>O=C(O)c1ccccc1SCC(F)(F)F,,C1CCOC1,,[Li+].[OH-],,test
US05986105,NC12C=CC(CC1)C1C(=O)NC(=O)C12>>NC12C=CC(CC1)C1CNCC12,,C1COCCO1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120316161A1,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc2c(c1)CCN2C>>CCCC(C(=O)O)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc2c(c1)CCN2C,,CO,,[Na+].[OH-],,test
US20150284321A1,Nc1ccccc1NC(=O)Nc1ccc(Cl)cc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=C(Nc1ccc(Cl)cc1)Nc1ccccc1NS(=O)(=O)c1ccc(Cl)cc1,,CCOC(C)=O,,CCN(CC)CC,,test
US20140148433A1,CC(C)(C)[Si](C)(C)Oc1c(N)nc(-c2nn(Cc3ccccc3F)c3ncccc23)nc1N>>Nc1nc(-c2nn(Cc3ccccc3F)c3ncccc23)nc(N)c1O,,C1CCOC1,,Cl,,test
US20060235057A1,CC(C)OB(OC(C)C)OC(C)C.Clc1ccc(Br)c(OCc2ccccc2)c1>>OB(O)c1ccc(Cl)cc1OCc1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US20090221555A1,CC1(C)CCCNc2ccc([N+](=O)[O-])cc21>>CC1(C)CCCNc2ccc(N)cc21,[Pd],CCO,,NN,O,test
US20100210674A1,O=C1Cc2ccc(Cl)cc2N1.O=Cc1cccnc1>>O=C1Nc2cc(Cl)ccc2/C1=C/c1cccnc1,,CO,,C1CCNCC1,,test
US20100105659A1,CC(=O)OCC(=O)Cl.Cc1ncccc1Oc1cc(Sc2ccccn2)cnc1Nc1nc(C2CC3CCC(C2)N3)ns1>>CC(=O)OCC(=O)N1C2CCC1CC(c1nsc(Nc3ncc(Sc4ccccn4)cc3Oc3cccnc3C)n1)C2,,ClCCl,,CCN(CC)CC,,test
US20160002252A1,CS(=O)(=O)Cl.FC(F)(F)c1cn(CC2CCNCC2)c2ncnc(Cl)c12>>CS(=O)(=O)N1CCC(Cn2cc(C(F)(F)F)c3c(Cl)ncnc32)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140275154A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2nc(NCC(F)(F)F)c(-c3cccc(C(=O)OC(C)(C)C)c3)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2nc(NCC(F)(F)F)c(-c3cccc(C(=O)O)c3)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040082629A1,Nc1nc(C(F)(F)F)c(I)s1.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>O=C(Nc1nc(C(F)(F)F)c(I)s1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,c1ccncc1,,Cl,,test
US20120264790A1,COC(=O)C1(NC(=O)c2ccc(OC)c(OCCc3cccc(C)c3)c2)CCCC(=O)CC1>>COC(=O)C1(NC(=O)c2ccc(OC)c(OCCc3cccc(C)c3)c2)CCCC(O)CC1,,C1CCOC1,,CO,[BH4-].[Na+],test
US20070066618A1,CCc1nc2c(C)cc(C)nc2n1-c1ccc(CCCl)cc1.CN>>CCc1nc2c(C)cc(C)nc2n1-c1ccc(CCNC)cc1,,O,,,,test
US05356893,COc1cc(C(C)=O)ccc1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1cc(C(C)=O)ccc1OS(=O)(=O)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US05041455,CCOCCOc1nsnc1-c1cccnc1.CI>>CCOCCOc1nsnc1-c1ccc[n+](C)c1.[I-],,CC(C)=O,,,,test
US20160039745A1,COC(=O)[C@@]1(c2cccc(F)c2C)CCC(=O)C1>>Cc1c(F)cccc1[C@]1(C(=O)O)CCC(=O)C1,,CO,,[Na+].[OH-],,test
US20050014786A1,O=S(=O)(Cl)c1ccccc1.O=S(=O)(NC1CNc2ccc(Br)cc2C1)c1ccccc1>>O=S(=O)(NC1Cc2cc(Br)ccc2N(S(=O)(=O)c2ccccc2)C1)c1ccccc1,,c1ccncc1,,,,test
US05763437,O=C1C(N2C(=O)c3ccccc3C2=O)N=C(C2CCCCC2)c2ccccc2N1Cc1ccccn1>>NC1N=C(C2CCCCC2)c2ccccc2N(Cc2ccccn2)C1=O,,C1CCOC1,,NN,O,test
US08138168B1,CC(C)(C)OC(=O)N[C@@H](CC(=O)O)Cc1ccc2ccccc2c1.Cc1nc2ccccc2n1C1CCCNC1>>Cc1nc2ccccc2n1C1CCCN(C(=O)C[C@@H](Cc2ccc3ccccc3c2)NC(=O)OC(C)(C)C)C1,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040082571A1,CSc1[nH]nc(-c2ccc(F)cc2)c1Cl.O=C(CCl)N1CCN(c2ccc(F)cc2)CC1>>CSc1c(Cl)c(-c2ccc(F)cc2)nn1CC(=O)N1CCN(c2ccc(F)cc2)CC1,,CCCCCC,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04613676,CC(C)(C)OC(=O)CCCCCCC[NH-].CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O.CC(C)C[C@H](N)C(=O)N[C@H](C(=O)O)C(C)C>>CC(C)(C)OC(=O)CCCCCCC[NH-].CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@H](C(=O)O)C(C)C,,CO,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20060135575A1,CC(=O)OC(C)=O.CCCCc1ccc(O)cc1>>CCCCc1ccc(OC(C)=O)cc1,,ClCCl,,c1ccncc1,,test
US20100137313A1,CCOC(=O)c1cc(-c2cnc(Nc3cc(C)cc(OC)c3)nc2-n2nc(C(F)(F)F)cc2C)cn(CC)c1=O>>CCn1cc(-c2cnc(Nc3cc(C)cc(OC)c3)nc2-n2nc(C(F)(F)F)cc2C)cc(C(=O)O)c1=O,,C1CCOC1,,O,[Na+].[OH-],test
US20130345181A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Clc1c(-c2cnco2)[nH]c2cc(Br)ncc12>>CC(C)(C)OC(=O)n1c(-c2cnco2)c(Cl)c2cnc(Br)cc21,CN(C)c1ccncc1,CCOC(C)=O,,CCN(CC)CC,,test
US05073565,CC(C)c1cccc(C(C)C)c1N=C=O.Nc1nnn(Cc2ccccc2)n1>>CC(C)c1cccc(C(C)C)c1NC(=O)Nc1nnn(Cc2ccccc2)n1,,ClCCl,,CCN(CC)CC,,test
US20120101137A1,Cc1sc([C@@H]2C[C@@H](F)CN2C(=O)CNCC(=O)OC(C)(C)C)cc1C(=O)Nc1ncc(F)s1.O=C(O)C(F)(F)F>>Cc1sc([C@@H]2C[C@@H](F)CN2C(=O)CNCC(=O)O)cc1C(=O)Nc1ncc(F)s1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20110070192A1,O=C(Cl)c1ccc(Cl)cc1.O=c1cc[nH]c(=O)[nH]1>>O=C(c1ccc(Cl)cc1)n1ccc(=O)[nH]c1=O,,CN(C)C=O,,c1ccncc1,,test
US20080132503A1,CC(=O)Oc1cccc(C(=O)Nc2cc(-c3cccs3)ccc2N)c1>>Nc1ccc(-c2cccs2)cc1NC(=O)c1cccc(O)c1,,CO,,CCN(CC)CC,,test
US20150274696A1,CC(C)(O)C(F)CNC(=O)c1cnc(Cl)cc1N[C@H]1CCCC(F)C1.Nc1ccc2ncsc2c1>>CC(C)(O)C(F)CNC(=O)c1cnc(Nc2ccc3ncsc3c2)cc1NC1CCCC(F)C1,,CC#N,O,O=C(O)C(F)(F)F,,test
US20100063068A1,CN(C(=O)OC(C)(C)C)C(=O)c1c(-c2ccc(F)cc2)nn2c(F)cc(Cl)cc12.Cc1ccc(C(=O)O)cc1B1OC(C)(C)C(C)(C)O1>>Cc1ccc(C(=O)O)cc1-c1cc(F)n2nc(-c3ccc(F)cc3)c(C(=O)N(C)C(=O)OC(C)(C)C)c2c1,,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20040171881A1,CN(C)Cc1cc(C#N)ccn1>>CN(C)Cc1cc(CN)ccn1,[Pd],CO,,Cl,[H][H],test
US04855314,CS(=O)(=O)Cl.Nc1ccc(CS(=O)(=O)Oc2ccccc2)cc1>>CS(=O)(=O)Nc1ccc(CS(=O)(=O)Oc2ccccc2)cc1,,CCOC(C)=O,c1ccncc1,Cl,,test
US20020111333A1,CCCn1c(=O)[nH]c(=S)c2[nH]c(C34CCC(O)(CC3)CC4)nc21.CI>>CCCn1c(=O)nc(SC)c2[nH]c(C34CCC(O)(CC3)CC4)nc21,,CCO,O,Cl,[Na+].[OH-],test
US05712299,Cc1ncsc1C(N=[N+]=[N-])c1ccoc1>>Cc1ncsc1C(N)c1ccoc1,[Pd],CCO,,,,test
US20120283256A1,Cc1cc(N)cc(CN2CCCC2)c1N1CCOCC1.Clc1ccc2c(Cl)ccnc2c1>>Cc1cc(Nc2ccnc3cc(Cl)ccc23)cc(CN2CCCC2)c1N1CCOCC1,,CC#N,,Cl,,test
US20080242665A1,BrBr.Cc1cccnc1C>>Cc1cc(Br)cnc1C,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20150282482A1,COC(=O)c1cc2cccc(Br)c2s1.COc1ccccc1B(O)O>>COC(=O)c1cc2cccc(-c3ccccc3OC)c2s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US20090253908A1,C[C@H]1CN(Cc2cccc(-c3ccc(F)c(CN)c3)c2)CCN1C(=O)OC(C)(C)C.O=C(O)c1ccc2c(c1)OCO2>>C[C@H]1CN(Cc2cccc(-c3ccc(F)c(CNC(=O)c4ccc5c(c4)OCO5)c3)c2)CCN1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160155949A1,CI.c1ccc2c(c1)c1cccnc1c1ncccc21>>C[n+]1cccc2c3ccccc3c3cccnc3c21.[I-],,CC#N,,,,test
US04866196,C1N2CN3CN1CN(C2)C3.O=C(CCl)c1ccc(OCc2ccccc2)cc1>>NCC(=O)c1ccc(OCc2ccccc2)cc1,,ClC(Cl)Cl,,CCO,Cl,test
US20160031875A1,COC(=O)C[C@@H]1C[C@@H]2CC[C@H]1O2>>O=C(O)C[C@@H]1C[C@@H]2CC[C@H]1O2,,C1CCOC1,O,[Li]O,,test
US05556864,CN(C)CC(O)COc1ccccc1CCCc1ccccc1.Cl>>CN(C)CC(O)COc1ccccc1CCCc1ccccc1.Cl,,C1COCCO1,CCOC(C)=O,,,test
US20160158207A1,CC(=O)N1CCc2c(c(N3CC(CC(F)F)Cc4ccccc43)nn2[C@H]2CCOC2)C1.O=C1CCC(=O)N1Br>>CC(=O)N1CCc2c(c(N3CC(CC(F)F)Cc4cc(Br)ccc43)nn2[C@H]2CCOC2)C1,,ClCCl,,,,test
US20120010235A1,CC1NC(C(=O)OC(C)(C)C)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.O=C(O)C(F)(F)F>>CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20040133008A1,CC1CCNCC1.COc1ccc(C(=O)OCc2ccccc2)c(OS(=O)(=O)C(F)(F)F)c1>>COc1ccc(C(=O)OCc2ccccc2)c(N2CCC(C)CC2)c1,,CC#N,,,,test
US20090209585A1,CC(=O)OCC(=O)Cl.CCOC(=O)C1=CCCCC1S(=O)(=O)Nc1ccc(F)cc1Cl>>CCOC(=O)C1=CCCCC1S(=O)(=O)N(C(=O)COC(C)=O)c1ccc(F)cc1Cl,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20030114432A1,CCOC(=O)c1nn(-c2ccc3c(c2)OCO3)c2c1COc1ccc([N+](=O)[O-])cc1-2>>CCOC(=O)c1nn(-c2ccc3c(c2)OCO3)c2c1COc1ccc(N)cc1-2,[Ni],CN(C)C=O,,,,test
US20160050924A1,COC(=O)c1cnn(-c2c(C)ccc[n+]2[O-])c1C.O=P(Cl)(Cl)Cl>>Cc1ccc(Cl)nc1-n1ncc(C(=O)O)c1C,,Cc1ccccc1,,,,test
US20030228469A1,C=CCCCCCCCCCCCCCCCCCCCC(=O)O>>C=CCCCCCCCCCCCCCCCCCCCCO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150210682A1,COc1ccc(C(=O)CC(=O)C(F)(F)F)cc1OC.NO>>COc1ccc(C2=NOC(O)(C(F)(F)F)C2)cc1OC,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20150336949A1,CC(C)(C)OC(=O)N1CC=C(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2F)CC1.Cc1ccc(S(=O)(=O)n2cc(-c3cn(Cc4cccc(F)c4)nc3C)c3cc(Br)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3cn(Cc4cccc(F)c4)nc3C)c3cc(-c4ccc(C5=CCN(C(=O)OC(C)(C)C)CC5)c(F)c4)cnc32)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US04689330,CCOC(=O)N1CCC(O)(C[N+](=O)[O-])CC1>>CCOC(=O)N1CCC(O)(CN)CC1,[Pd],CC(=O)O,,CO,[H][H],test
US20100048658A1,CNc1c(N)cccc1N.Cc1cc(C)c(CC(=O)O)c(C)c1>>Cc1cc(C)c(Cc2nc3cccc(N)c3n2C)c(C)c1,,C1CCOC1,,,,test
US20130324404A1,COCCON1C(=O)C(c2cc(C)c(C)cc2Cl)=C(O)C12CCN(OC)CC2.O=S(=O)(Cl)Cl>>COCCON1C(=O)C(Cl)(c2cc(C)c(C)cc2Cl)C(=O)C12CCN(OC)CC2,,ClC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20110178063A1,CCn1nc(C)cc1C(=O)O.Nc1cc(-c2cccc3[nH]ccc23)cc2[nH]ncc12>>CCn1nc(C)cc1C(=O)Nc1cc(-c2cccc3[nH]ccc23)cc2[nH]ncc12,,CCN(C(C)C)C(C)C,CN(C)C=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20060199853A1,COC(=O)[C@@H]1CC(O)CN1>>O=C(O)[C@@H]1CC(O)CN1,,CCN(CC)CC,,C[Si](C)(C)Cl,,test
US20120245210A1,Br.Cc1nccn1-c1ccc(N)cc1>>Cc1nccn1-c1ccc(Br)cc1,,O,,O=N[O-].[Na+],,test
US20050148604A1,COc1cc(N)ccc1-c1nc2c(c(C3CCCCC3)nn2C)c(=O)[nH]1.O=S(=O)(Cl)CCCCl>>COc1cc(N2CCCS2(=O)=O)ccc1-c1nc2c(c(C3CCCCC3)nn2C)c(=O)[nH]1,,c1ccncc1,,O=C([O-])O.[Na+],,test
US20090291917A1,CN(C)CCO.O=C(O)c1ccc(Oc2ccc3c(c2)COB3O)cc1>>CN(C)CCOC(=O)c1ccc(Oc2ccc3c(c2)COB3O)cc1,,CN(C)C=O,,CCN=C=NCCCN(C)C,,test
US03994871,CC(=O)NCSC[C@H](NC(=O)[C@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O.COC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](N)[C@@H](C)OC(C)(C)C>>COC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](NC(=O)[C@H](CSCNC(C)=O)NC(=O)[C@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(c1ccccc1)(c1ccccc1)c1ccccc1)[C@@H](C)OC(C)(C)C,,CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20110207709A1,COc1ccccc1C1CCN(C(=O)C(F)(F)F)C1>>O=C(N1CCC(c2ccccc2O)C1)C(F)(F)F,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20160158207A1,CNC(=O)n1ccnc1.Cc1ccc(-c2cc3c(cc2C(F)F)N(c2nn(C4CCOCC4)c4c2CNCC4)CCC3)s1>>CNC(=O)N1CCc2c(c(N3CCCc4cc(-c5ccc(C)s5)c(C(F)F)cc43)nn2C2CCOCC2)C1,,ClCCl,,,,test
US20060189627A1,NOCc1ccccc1.O=C1CCc2cc(Br)ccc21>>Brc1ccc2c(c1)CC/C2=N\OCc1ccccc1,,CCO,,Cl,c1ccncc1,test
US20080004273A1,CCOC(=O)C(C(=O)OCC)C(Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)c(F)c1)C(F)(F)F>>COc1cc2nccc(Oc3ccc(NC(CC(=O)O)C(F)(F)F)cc3F)c2cc1OC,,CCO,O,[Na+].[OH-],,test
US20140155407A1,Cc1cccnc1Br.O=C1CCC(=O)N1Br>>BrCc1cccnc1Br,,ClC(Cl)(Cl)Cl,,,,test
US20090239854A1,CC1(C)CCCCN1C(=O)CBr.CN1CCC(=O)CC1.NNc1ccc(Cl)cc1>>CN1CCc2c(c3cc(Cl)ccc3n2CC(=O)N2CCCCC2(C)C)C1,,CCN(CC)CC,,Cl,,test
US20090233936A1,COc1ccc(C(c2ccc(OC)cc2)N2C[C@@H](C(=O)O)[C@H](c3cc(F)c(F)cc3F)CC2=O)cc1.OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COc1ccc(C(c2ccc(OC)cc2)N2C[C@@H](NC(=O)OCc3ccccc3)[C@H](c3cc(F)c(F)cc3F)CC2=O)cc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20110274657A1,CC(C)(C)OC(=O)CCN.N#Cc1ccc(S(=O)(=O)Cl)c(Cl)c1>>CC(C)(C)OC(=O)CCNS(=O)(=O)c1ccc(C#N)cc1Cl,,CCOC(C)=O,ClCCl,CCN(CC)CC,Cl,test
US06531502B1,CCOC(=O)CCc1c(C=O)[nH]c(C(=O)OCC)c1CC.CCOc1cccc(-c2ccc3c(c2)NC(=O)C3)c1>>CCOc1cccc(-c2ccc3c(c2)NC(=O)C3=Cc2[nH]c(C(=O)O)c(C)c2CCC(=O)O)c1,C1CCNCC1,CCO,,,,test
US20080004312A1,NCCN1CCc2ccccc2C1.O=C=Nc1cccc([N+](=O)[O-])c1>>O=C(NCCN1CCc2ccccc2C1)Nc1cccc([N+](=O)[O-])c1,,ClCCl,,,,test
US20060084640A1,C1CNCCN1.C[Si](C)(C)CCOCn1c(Br)nc(Cl)c1Cl>>C[Si](C)(C)CCOCn1c(N2CCNCC2)nc(Cl)c1Cl,,ClCCl,,,,test
US20140323477A1,CN(CCCO)C(=O)OC1c2ccccc2-c2ccccc21>>CN(CCC=O)C(=O)OC1c2ccccc2-c2ccccc21,,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20110190272A1,CC(=O)O.NC(=O)c1nnc2cc(Br)ccc2c1N.O>>O=C(O)c1nnc2cc(Br)ccc2c1O,,C1COCCO1,O,[K+].[OH-],,test
US20070078263A1,COC(=O)CCCN1CCC[C@H]1COc1ccc(Cc2ccccc2)cc1>>O=C(O)CCCN1CCC[C@H]1COc1ccc(Cc2ccccc2)cc1,,CO,O,[Na+].[OH-],,test
US20120129856A1,COCCN.O=C(CCl)Nc1ccc2c(c1)OCCO2>>COCCNCC(=O)Nc1ccc2c(c1)OCCO2,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04954498,COc1ccc(C(=O)Nc2cc3c(cc2[N+](=O)[O-])NC(=O)CC3(C)C)cc1>>COc1ccc(-c2nc3cc4c(cc3[nH]2)C(C)(C)CC(=O)N4)cc1,[Pd],CCO,,,,test
US20110190269A1,CCOC(=O)C(=O)CC(=O)c1ccc(F)c(Cl)c1.COc1cc(Nc2nnc(N)[nH]2)ccc1-n1cnc(C)c1>>CCOC(=O)c1cc(-c2ccc(F)c(Cl)c2)n2nc(Nc3ccc(-n4cnc(C)c4)c(OC)c3)nc2n1,,CC(=O)O,,,,test
US20120004203A1,CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(N(CC3CC3)C(=O)OCc3ccccc3)nc2N1c1cccc(C(F)(F)F)c1>>CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(NCC3CC3)nc2N1c1cccc(C(F)(F)F)c1,[Pd],CO,,,,test
US20110207770A1,Cc1ccc(O[C@H]2CN3CCC2CC3)cc1F.OC(c1ccccc1)(c1ccccc1)c1cc(CBr)on1>>Cc1ccc(O[C@H]2C[N+]3(Cc4cc(C(O)(c5ccccc5)c5ccccc5)no4)CCC2CC3)cc1F.[Br-],,CC#N,,,,test
US20110207704A1,CCOC(=O)/C(C)=C/[C@@H](C)Oc1ccc(-c2nc(-c3ccc(OC(C)C)c(C(F)(F)F)c3)no2)cc1>>CCOC(=O)C(C)C[C@@H](C)Oc1ccc(-c2nc(-c3ccc(OC(C)C)c(C(F)(F)F)c3)no2)cc1,[Pd],CCOC(C)=O,,,,test
US20150322076A1,COC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C#N)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)s1>>CC(C)(C#N)C[C@@H]1N[C@@H](C(=O)Nc2ccc(C(=O)O)s2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12,,C1CCOC1,CO,[Na+].[OH-],,test
US20150152113A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccccc1[C@@H]1C[C@H]1CNc1cn[nH]c(=O)c1Br>>COc1ccccc1[C@@H]1C[C@H]1CNc1cnn(C(=O)OC(C)(C)C)c(=O)c1Br,,ClCCl,,CCN(CC)CC,,test
US20080262042A1,CN(Cc1cc(-c2cccnc2F)n(S(=O)(=O)c2cccc(F)c2)c1)C(=O)OC(C)(C)C.Cl>>CNCc1cc(-c2cccnc2F)n(S(=O)(=O)c2cccc(F)c2)c1.Cl,,CCO,,CCOC(C)=O,,test
US20050152858A1,O=C(Cl)c1ccccc1.OCCc1ccccc1>>O=C(OCCc1ccccc1)c1ccccc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20100273764A1,CSc1ccc(C(O)c2ccc(F)nc2)cc1>>CSc1ccc(Cc2ccc(F)nc2)cc1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20110301142A1,Cc1noc(-c2ccc(CCl)cc2)c1NC(=O)OC(C)c1ccccc1Cl.O=C(O)Cc1ccc(S)cc1>>Cc1noc(-c2ccc(CSc3ccc(CC(=O)O)cc3)cc2)c1NC(=O)OC(C)c1ccccc1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04105664,C#CCBr.Clc1ccc2c(c1)CC(N1CCNCC1)c1cc(Cl)ccc1O2>>C#CCN1CCN(C2Cc3cc(Cl)ccc3Oc3ccc(Cl)cc32)CC1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US04694105,CCOCCOCCO.O=S(Cl)Cl>>CCOCCOCCO.[Cl-],,c1ccncc1,,,,test
US20110071126A1,C=C(OCC)C1(NS(=O)(=O)CC[Si](C)(C)C)c2cc(Br)ccc2CC12CCC(OC)CC2.O>>CCOC(=O)C1(NS(=O)(=O)CC[Si](C)(C)C)c2cc(Br)ccc2CC12CCC(OC)CC2,,CCOC(C)=O,,,,test
US04677129,CCCCCCCN1C(=O)C2CC(c3ccc([N+](=O)[O-])cc3)(C2)C1=O>>CCCCCCCN1C(=O)C2CC(c3ccc(N)cc3)(C2)C1=O,[Pd],CCO,,,,test
US20090012077A1,CC(C)(C)OC(=O)N1CCc2[nH]c3c(I)cccc3c2C1.OCCN1CCCCC1>>CC(C)(C)OC(=O)N1CCc2[nH]c3c(OCCN4CCCCC4)cccc3c2C1,[Cu]I,ClCCl,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20110184028A1,Cc1ncc(C(O)c2ccc(F)cc2)c2c1OC(C)(C)OC2.ClC(Cl)Cl>>Cc1ncc(C(=O)c2ccc(F)c(Cl)c2)c2c1OC(C)(C)OC2,O=[Mn]=O,,,,,test
US20110028455A1,CI.Cc1ncc(C#N)c(Cl)c1Br>>CCc1ncc(C#N)c(Cl)c1Br,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20130065906A1,CCc1cnc(Br)cn1.OC1CCNCC1>>CCc1cnc(N2CCC(O)CC2)cn1,,CC(C)O,,,,test
US05739336,COc1ccc(C(=O)N(C)OC)c(OC)c1.O=C1CCC(=O)N1Cl>>COc1cc(OC)c(C(=O)N(C)OC)cc1Cl,,CC#N,,,,test
US20060004043A1,C[C@H]1CCC[C@@H](C)N1C(=O)CCl.Oc1ccc2cc(Br)ccc2c1>>C[C@H]1CCC[C@@H](C)N1C(=O)COc1ccc2cc(Br)ccc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120322785A1,C[Mg]Cl.Cc1ccc(F)cc1C#Cc1cnc(Cl)cc1C=O>>CC(=O)c1cc(Cl)ncc1C#Cc1cc(F)ccc1C,,C1CCOC1,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US03994954,CCCCCC.Cc1ccc(S(=O)(=O)O)cc1.NC(=O)OCc1ccccc1.O=CC(=O)O>>CCCCOC(=O)C(NC(=O)OCc1ccccc1)OCCCC,,CCCCCC,,O,,test
US07012144B2,N#CC(CCOC1CCCCO1)(CN=[N+]=[N-])c1ccccn1>>N#CC(CCO)(CN=[N+]=[N-])c1ccccn1,,CO,Cl,O=C([O-])O.[Na+],,test
US20090011994A1,Cc1cc(Br)ccc1OCC(C)(C)O.O=c1[nH]ccnc1Sc1ccc(OC(F)(F)F)cc1>>Cc1cc(-n2ccnc(Sc3ccc(OC(F)(F)F)cc3)c2=O)ccc1OCC(C)(C)O,[Cu]I,C1COCCO1,,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20100094000A1,CC1(C)OB(c2ccc3c(c2)NC(=O)CO3)OC1(C)C.Cc1nn(C2CCSCC2)c(-c2ccc(F)cc2)c1Br>>Cc1nn(C2CCSCC2)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110034450A1,CC(CC(F)(F)F)C(=O)Cl.Cc1ccccc1>>Cc1ccc(C(=O)C(C)CC(F)(F)F)cc1,,ClCCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20040132772A1,COc1ccc(N(C(C)=O)[C@@H]2C[C@H](C)N(C(=O)c3ccccc3)c3ccccc32)cc1>>CC(=O)N(c1ccc(O)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccccc2)c2ccccc21,,ClCCl,,BrB(Br)Br,,test
US08129371B2,CCn1ncc2c(N3CC4CCC(C3)O4)nc(-c3ccc([N+](=O)[O-])cc3)nc21.O=C1CCC(=O)N1Br>>CCn1nc(Br)c2c(N3CC4CCC(C3)O4)nc(-c3ccc([N+](=O)[O-])cc3)nc21,,CN(C)C=O,,O,,test
US06531471B2,N.O=Cc1ccc(F)c(F)c1.[C-]#N>>N#CC(N)c1ccc(F)c(F)c1,,CO,,CCCCCC,CCOC(C)=O,test
US04933333,COc1ccc(COC(=O)N2C[C@@H](SC(C)=O)C[C@H]2C(=O)NCc2ccccc2)cc1>>CC(=O)S[C@@H]1CN[C@H](C(=O)NCc2ccccc2)C1,,O=C(O)C(F)(F)F,,COc1ccccc1,,test
US20020010186A1,CCC1=C(C(=O)OCc2ccccc2)C(c2ccc(F)c(F)c2)N(C(=O)OC)C(OC)=N1>>CCC1=C(C(=O)O)C(c2ccc(F)c(F)c2)N(C(=O)OC)C(=O)N1,[Pd],CO,,,,test
US20120214762A1,Nc1nccc(=O)[nH]1.O=[N+]([O-])O>>Nc1ncc([N+](=O)[O-])c(=O)[nH]1,,O,,O=S(=O)(O)O,,test
US20140142126A1,Nc1ncnc2c1c(I)cn2-c1cccc([N+](=O)[O-])c1.O=C1CCC(=O)N1Cl>>Nc1ncnc2c1c(I)c(Cl)n2-c1cccc([N+](=O)[O-])c1,,CN(C)C=O,,,,test
US20140228360A1,CCOC(=O)COc1cccc2cccnc12.NC[C@H](O)CN1Cc2ccccc2C1>>O=C(COc1ccccc1)NC[C@H](O)CN1Cc2ccccc2C1,,CCO,,,,test
US20090209571A1,COc1cccc(-c2nc(Cl)ccc2CC(=O)n2nnc3ccccc32)c1>>COc1ccc2c(O)cc3ccc(Cl)nc3c2c1,,CC(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US04366320,O=c1[nH][nH]c(=O)n1-c1c(F)c(F)c(F)c(F)c1F>>O=C1N=NC(=O)N1c1c(F)c(F)c(F)c(F)c1F,,CCOC(C)=O,,O=S(=O)([O-])[O-].[Na+].[Na+],,test
US20130331372A1,Cc1nc(N)ccc1Br.Cl>>Cc1nc(Cl)ccc1Br,,O,,O=N[O-].[Na+],,test
US20070072906A1,CCOC(=O)c1cccc(-n2c(Cl)ccc2-c2cc(Cl)ccc2OCc2ccccc2)n1>>O=C(O)c1cccc(-n2c(Cl)ccc2-c2cc(Cl)ccc2OCc2ccccc2)n1,,CCO,,[Na+].[OH-],,test
US20100168113A1,COc1cc(-c2nnc(-c3cccnc3C(F)(F)F)n2C)cc([N+](=O)[O-])c1OC>>Cn1c(-c2cc(O)c(O)c([N+](=O)[O-])c2)nnc1-c1cccnc1C(F)(F)F,,ClCCl,,BrB(Br)Br,,test
US05643923,CN1CCC(Oc2noc3ccc(Cl)cc23)CC1.Cl>>CN1CCC(Oc2noc3ccc(Cl)cc23)CC1.Cl,,C1COCCO1,CCO,,,test
US20080021217A1,CC(C)C(=O)Cl.O=C(NCc1nc(-c2ccncc2)n[nH]1)c1ccc(O)cc1O>>CC(C)C(=O)Oc1ccc(C(=O)NCc2nc(-c3ccncc3)n[nH]2)c(O)c1,,c1ccncc1,,,,test
US04892576,COC(=S)c1c(Cc2ccccc2)n[nH]c1NC(C)=O.O.O=S(=O)(Cl)Cl>>COC(=O)c1c(S(=O)(=O)Cl)n[nH]c1NC(C)=O,,ClCCl,,,,test
US05070087,CCOC(=O)C(=O)c1ccc(O)c(OC)c1.ClCCCBr>>CCOC(=O)C(=O)c1ccc(OCCCCl)c(OC)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06627629B2,CCOC(=O)C1=C(N[C@H](C)c2ccccc2)COCC1>>CCOC(=O)[C@@H]1CCOC[C@H]1N[C@H](C)c1ccccc1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20130310379A1,COC(=O)c1ccc(CBr)cc1.Cc1cccc(O)n1>>COC(=O)c1ccc(COc2cccc(C)n2)cc1,,CCCCCC,,,,test
US20160068496A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Nc1cc(C(F)(F)F)c(Br)cn1>>CC1(C)OB(c2cnc(N)cc2C(F)(F)F)OC1(C)C,,C1COCCO1,,ClCCl,CC(=O)[O-].[K+],test
US20160024103A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(CS(C)(=O)=O)c(OC(C)C)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(CS(C)(=O)=O)c(O)cc12,,ClCCl,,ClB(Cl)Cl,,test
US20140364414A1,CC(C)(C)OC(=O)c1ccc(-c2cnc(N3CCOCC3)c3nc(C#Cc4nc5ccccc5s4)cn23)cc1>>O=C(O)c1ccc(-c2cnc(N3CCOCC3)c3nc(C#Cc4nc5ccccc5s4)cn23)cc1,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20020165253A1,CCOC(=O)c1ccc(N)cc1.O=C1CCC(=O)N1I>>CCOC(=O)c1ccc(N)c(I)c1,,CN(C)C=O,,O,,test
US20120202788A1,Nc1cc(Nc2ncc(F)c3nc(-c4c(F)cccc4Cl)sc23)ncn1>>Nc1cc(Nc2ncc(F)c3nc(-c4c(F)cccc4Cl)sc23)ncn1,,ClCCl,,Cl,O=C(O)C(F)(F)F,test
US20120040985A1,CC(C)(c1ccc(Cl)c(Cl)c1)c1cncn1-c1ccc(F)cc1.CN(C)C=O>>CC(C)(c1ccc(Cl)c(Cl)c1)c1cnc(C=O)n1-c1ccc(F)cc1,,CN(C)C=O,,C1CCOC1,[Li]CCCC,test
US04775692,C=[N+]=[N-].O=C(O)c1ccccc1Cl>>COC(=O)c1ccccc1Cl,,CCOCC,,,,test
US20100003597A1,CCCCCCP(CCCCCC)CCCCCC.CI>>CCCCCC[P+](C)(CCCCCC)CCCCCC.[I-],,CCCCCC,,,,test
US20060154899A1,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].N#CCCCCCCN1C(=O)SC[C@@H]1/C=C/C(O)Cc1ccccc1>>O=C1SC[C@H](/C=C/C(O)Cc2ccccc2)N1CCCCCCc1nnn[nH]1,,Cc1ccccc1,,CCOC(C)=O,,test
US20010039279A1,C=O.CC(C)(C)OC(=O)NC[C@@H]1CNC[C@H]1CNC(=O)OC(C)(C)C>>CN1C[C@@H](CNC(=O)OC(C)(C)C)[C@H](CNC(=O)OC(C)(C)C)C1,,CC#N,CC(=O)O,[Na+].[OH-],,test
US04083980,CCOC(=O)c1ccc2nc3ccc4ccccc4n3c(=O)c2c1>>O=C(O)c1ccc2nc3ccc4ccccc4n3c(=O)c2c1,,O,,Cl,[Na+].[OH-],test
US20050227987A1,CCCc1ccc(C(=O)Cl)cc1.Nc1ccc2c(c1)CCC2=O>>CCCc1ccc(C(=O)Nc2ccc3c(c2)CCC3=O)cc1,,C1CCOC1,,CCN(CC)CC,,test
US08318757B2,O=C1c2ccccc2C(=O)N1Cc1ccc(C2=NOC(c3cc(Br)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1Cl>>NCc1ccc(C2=NOC(c3cc(Br)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1Cl,,CCO,,NN,O,test
US20150315198A1,COc1cc(C)c(Br)c(C)n1.N#C[Cu]>>COc1cc(C)c(C#N)c(C)n1,,O,,CN(C)C=O,,test
US20100278833A1,COC(=O)c1sc(-n2cnc3cc(CO[Si](C)(C)C(C)(C)C)ncc32)cc1O.C[C@H](O)c1ccccc1C(F)(F)F>>COC(=O)c1sc(-n2cnc3cc(CO[Si](C)(C)C(C)(C)C)ncc32)cc1O[C@H](C)c1ccccc1C(F)(F)F,,ClCCl,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100160280A1,CC(=O)N1CC=C(c2cccnc2Oc2ccc(N)cc2)CC1>>CC(=O)N1CCC(c2cccnc2Oc2ccc(N)cc2)CC1,[Pd],CCO,,,,test
US20160222012A1,CC(C)(C)OC(=O)N1CCCC1c1cc2ccc(F)cc2nc1-c1ccccn1.O=C(O)C(F)(F)F>>Fc1ccc2cc(C3CCCN3)c(-c3ccccn3)nc2c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20030139435A1,Cc1ccc(-c2nnc[nH]2)cc1Nc1ncnc(N(C)CC(C)(C)C)c1[N+](=O)[O-]>>Cc1ccc(-c2nnc[nH]2)cc1Nc1ncnc(N(C)CC(C)(C)C)c1N,[Pd],CO,,,,test
US20050256311A1,CC(C)(C)NS(=O)(=O)c1ccc(I)cc1.COCCBr>>COCCN(C(C)(C)C)S(=O)(=O)c1ccc(I)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20060178507A1,COC(=O)C(C#N)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>COC(=O)C(CN)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F,[Ni],CO,,N,,test
US20160222028A1,COC(=O)c1ccc2c(c1)OC[C@H](C(F)(F)F)NC2.O=C(Cl)C1CCOCC1>>COC(=O)c1ccc2c(c1)OC[C@H](C(F)(F)F)N(C(=O)C1CCOCC1)C2,,ClCCl,,CCN(CC)CC,,test
US20080234261A1,CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(N)c3)cc21.O=C(Cl)c1ccc(=O)[nH]c1>>CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(NC(=O)c4ccc(=O)[nH]c4)c3)cc21,,c1ccncc1,,O,,test
US20100261698A1,CCC(=O)c1cccnc1.Cl.NNc1ccc(Br)cc1>>Cc1c(-c2cccnc2)[nH]c2ccc(Br)cc12.Cl,,C1COCCO1,CCO,Cl,,test
US20100137305A1,CC(C)(C)OC(=O)N1CC[C@H](O)C1.CC(C)I>>CC(C)O[C@H]1CCN(C(=O)OC(C)(C)C)C1,O=[Ag-],,,,,test
US04742069,CC(N)=CC(=O)CS(=O)(=O)NC(C)C.C[C@H](OC(=O)CC(=O)C=Cc1cccc([N+](=O)[O-])c1)c1ccccc1>>CC1=C(C(=O)CS(=O)(=O)NC(C)C)[C@@H](c2cccc([N+](=O)[O-])c2)C(C(=O)O[C@@H](C)c2ccccc2)=C(C)N1,,CCOCC,CN(C)C=O,CC(C)O,,test
US20070254869A1,CC(=O)OC(C)=O.CC(C)OC(=O)N1CCCC(NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccc3c(c21)CCC3>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2c1ccc1c2CCC1,,ClCCl,,Cl,c1ccncc1,test
US20040224952A1,O=[N+]([O-])c1cc(Br)ccc1S>>Nc1cc(Br)ccc1S,[Ni],C1CCOC1,,[H][H],,test
US20120108582A1,CCOC(=O)C1C(=O)N([C@@H](C)c2ccccc2)C[C@H]1C1(CO)CC1.II>>CCOC(=O)C1C(=O)N([C@@H](C)c2ccccc2)C[C@H]1C1(CI)CC1,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050238909A1,Brc1ccccc1-c1ccccc1.O=C1C=CC=C2C1=Cc1ccccc12>>c1ccc2c(c1)-c1ccccc1C21c2ccccc2-c2ccccc21,,CCOCC,,,,test
US20060211734A1,CC(C)(C)OC(=O)N1CCC(Oc2cccc(NC(=O)c3ccc(F)cc3Cl)c2)CC1.Cl>>Cl.O=C(Nc1cccc(OC2CCNCC2)c1)c1ccc(F)cc1Cl,,C1COCCO1,,,,test
US20020025963A1,O=[N+]([O-])c1ccc(N2CCOCC2)cc1F>>Nc1ccc(N2CCOCC2)cc1F,[Pd],CO,,,,test
US05514680,O=c1[nH]c2c(Cl)cc(C(F)(F)F)c([N+](=O)[O-])c2[nH]c1=O>>Nc1c(C(F)(F)F)cc(Cl)c2[nH]c(=O)c(=O)[nH]c12,,CCO,,Cl[Sn]Cl,,test
US20100286123A1,Cc1c(C(C)(C(=O)[O-])C(C)(C)C)ccc2c1COC2=O>>Cc1c(C(C)C(=O)O)ccc2c1COC2=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060106032A1,COc1ccc(CNN)cc1.Cc1ccc(C(=O)c2ccccc2)cc1>>COc1ccc(CN/N=C(/c2ccccc2)c2ccc(C)cc2)cc1,,CO,,CC(=O)O,,test
US20050209225A1,CCOC(=O)C1CC1c1cc2cc(OCCCNc3ccccn3)ccc2[nH]1.CO>>O=C(O)C[C@@H]1C[C@H]1c1cc2cc(OCCCNc3ccccn3)ccc2[nH]1,,O,,Cl,[Na+].[OH-],test
US20120071503A1,COC(=O)c1cc(-c2cccc(COc3ccc4c(c3)CN(C3CCCC3)C4=O)c2)ccc1Cl>>O=C(O)c1cc(-c2cccc(COc3ccc4c(c3)CN(C3CCCC3)C4=O)c2)ccc1Cl,,C1CCOC1,,[Li+].[OH-],,test
US20140163012A1,CC(C)(C)OC(=O)N1CCc2oc3cc(-n4ccc(OCc5ccc(Cl)cn5)cc4=O)ccc3c2CC1>>O=c1cc(OCc2ccc(Cl)cn2)ccn1-c1ccc2c3c(oc2c1)CCNCC3,,CCOCC,CO,Cl,O=C([O-])O.[Na+],test
US20050261294A1,CC(C)c1ccc(-c2csc(N)n2)cc1.O=C(Cl)C1CCCCC1>>CC(C)c1ccc(-c2csc(NC(=O)C3CCCCC3)n2)cc1,,ClCCl,,c1ccncc1,,test
US06828317B2,CC(C)(C)OC(=O)NN.[N-]=[N+]=NC[C@H]1CN(c2ccc(C(=O)O)c(F)c2)C(=O)O1>>CC(C)(C)OC(=O)NNC(=O)c1ccc(N2C[C@H](CN=[N+]=[N-])OC2=O)cc1F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04576746,CCC1C(=O)NC1CCOCc1ccccc1>>CCC1C(=O)NC1CCO,[Pd],CC(=O)O,,,,test
US20150133428A1,CC1(C(=O)O)CC(F)(F)C1>>CC1(CO)CC(F)(F)C1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090240052A1,CC(C)(C)OC(=O)c1ccc(-c2ccc(O)c(Cl)c2)cc1NC(=O)c1ccccc1>>O=C(Nc1cc(-c2ccc(O)c(Cl)c2)ccc1C(=O)O)c1ccccc1,,O=C(O)C(F)(F)F,,,,test
US04252739,CCOC(=O)CC(=O)OCC.ClC/C=C/CCl>>C=CC1CC1(C(=O)OCC)C(=O)OCC,,ClCCl,,[K+].[OH-],,test
US20060292079A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.OC(COC(COCc1ccccc1)COCc1ccccc1)COC(COCc1ccccc1)COCc1ccccc1>>O=S(=O)(OC(COC(COCc1ccccc1)COCc1ccccc1)COC(COCc1ccccc1)COCc1ccccc1)C(F)(F)F,,ClCCl,,Cc1cccc(C)n1,,test
US20040180934A1,COC(=O)CC1CCn2c1cc1c(C3=CCCC3)cc(F)cc12>>COC(=O)CC1CCn2c1cc1c(C3CCCC3)cc(F)cc12,[Pd],CCO,,,,test
US20120264737A1,CCc1cc(C)c(I)cc1C(=O)O.CN(C)C=O>>CCc1cc(C)c(C=O)cc1C(=O)O,,C1CCOC1,,[Li]CCCC,,test
US20090291079A1,CN1CCNCC1.O=C(Nc1ccc(C(=O)O)cc1)Nc1ccc(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)cc1>>CN1CCN(C(=O)c2ccc(NC(=O)Nc3ccc(-c4nc(N5CCOCC5)nc(N5CCOCC5)n4)cc3)cc2)CC1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050065151A1,COc1cnc(N2CCOCC2)c2sc(N)nc12.O=C(O)c1ccc(N2CCOCC2)cc1>>COc1cnc(N2CCOCC2)c2sc(NC(=O)c3ccc(N4CCOCC4)cc3)nc12,,C1CCOC1,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06303790B1,CN1CCNCC1.CNC(=O)c1ccc(Cl)nc1.Cc1ccccc1[Mg]Cl>>CNC(=O)C1=CN=C(N2CCN(C)CC2)CC1c1ccccc1C,,C1CCOC1,,[Na+].[OH-],[Cl-].[NH4+],test
US20080103129A1,C[Mg]Br.O=Cc1cccnc1Br>>CC(O)c1cccnc1Br,,C1CCOC1,,,,test
US20090182023A1,CC(=O)NCCC1CCc2ccc(N)c(O)c21.O=C(Cl)Cc1ccccc1>>CC(=O)NCCC1CCc2ccc(NC(=O)Cc3ccccc3)c(O)c21,,c1ccncc1,,Cl,O,test
US20110306588A1,CC1(C=C(Br)Br)COC1.C[Si](C)(C)Cl>>CC1(C#C[Si](C)(C)C)COC1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20090291940A1,Cc1cc(N(C)C)nc(Cl)n1.N[C@H]1CCN(C(=O)Cc2ccc(OC(F)(F)F)cc2)C1>>Cc1cc(N(C)C)nc(N[C@H]2CCN(C(=O)Cc3ccc(OC(F)(F)F)cc3)C2)n1,,CC(C)O,,CCN(CC)CC,Cl,test
US04088695,O=C(C=CC1CCC2(OCCO2)C1CCCCCCCO)C1CCCCC1>>O=C(CCC1CCC2(OCCO2)C1CCCCCCCO)C1CCCCC1,[Pd],CCO,,[H][H],,test
US20130096130A1,COC(=O)CC1=CC[C@@H](c2cccc(F)c2F)[C@H](NC(=O)OC(C)(C)C)c2nccnc21>>CC(C)(C)OC(=O)N[C@@H]1c2nccnc2C(CC(=O)O)=CC[C@H]1c1cccc(F)c1F,,C1CCOC1,CO,[Li+].[OH-],,test
US04309426,CCNC(=S)NN.O=C(CCl)c1ccc(F)cc1>>CCNC1=NN=C(c2ccc(F)cc2)CS1.Cl,,CO,,,,test
US20060276465A1,CCC1(CC)CC=C(B2OC(C)(C)C(C)(C)O2)CC1.COc1ccc(Br)c([N+](=O)[O-])c1>>CCC1(CC)CC=C(c2ccc(OC)cc2[N+](=O)[O-])CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20130224659A1,Cc1ccc(S(=O)(=O)OCC(F)(F)F)cc1.Oc1cccc2ccccc12>>FC(F)(F)COc1cccc2ccccc12,,Cc1ccccc1,O,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US05036075,O=S1(=O)c2cccc3cccc(c23)N1CCCCl.c1ccc(N2CCNCC2)nc1>>O=S1(=O)c2cccc3cccc(c23)N1CCCN1CCN(c2ccccn2)CC1,,Cc1ccccc1,,CCN(CC)CC,,test
US20060199826A1,O=C1OC[C@@H]2[C@H](c3ccccc3)[C@]12NS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)on2)s1.[Li]O>>O=C(O)C1(NS(=O)(=O)c2ccc(-c3cc(C(F)(F)F)on3)s2)C(CO)C1c1ccccc1,,O,,C1CCOC1,,test
US20150166480A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)cc2F)cc1>>O=S(=O)(Oc1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)cc2F)cc1)C(F)(F)F,,ClCCl,,O,c1ccncc1,test
US20130217666A1,C#C[C@]1(O)CCN(C)C1=O.Cc1nc2ccccc2n1Cc1c(C(N)=O)nc2n1CCOc1ccc(Br)cc1-2>>Cc1nc2ccccc2n1Cc1c(C(N)=O)nc2n1CCOc1ccc(C#C[C@]3(O)CCN(C)C3=O)cc1-2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CS(C)=O,,,,test
US20080085895A1,CC(C)C(=O)Cl.NCCC[C@H]1COCc2nc3c(N)nc4ccccc4c3n21>>CC(C)C(=O)NCCC[C@H]1COCc2nc3c(N)nc4ccccc4c3n21,,ClCCl,,CCN(CC)CC,,test
US20140296208A1,CC(C)[Si](C#Cc1cc(Nc2cc(Oc3ccc(N)c4ccccc34)ccn2)cc(C(=O)NCCN2CCOCC2)c1)(C(C)C)C(C)C.CNC(=O)c1cc(C(C)(C)C)cc(NC(=O)Oc2ccccc2)c1OC>>CNC(=O)c1cc(C(C)(C)C)cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(C#C[Si](C(C)C)(C(C)C)C(C)C)cc(C(=O)NCCN5CCOCC5)c4)c3)c3ccccc23)c1OC,,C1CCOC1,,CCN(CC)CC,,test
US20150005257A1,Clc1ncnc(Cl)c1C1OCCO1.OCc1ccc(C(F)(F)F)cc1>>FC(F)(F)c1ccc(COc2ncnc(Cl)c2C2OCCO2)cc1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20110015202A1,CI.Cc1nc(C#Cc2cccc(Cl)c2)cn1-c1cc[nH]c(=O)c1>>Cc1nc(C#Cc2cccc(Cl)c2)cn1-c1ccn(C)c(=O)c1,,CCOC(C)=O,COCCOC,O=C([O-])[O-].[K+].[K+],,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(-c2ccc(O)cc2)c2ccnn12.C[C@@H]1O[C@H]1C>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(-c2ccc(O[C@H](C)[C@H](C)O)cc2)c2ccnn12,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20160039745A1,Cc1c(F)cccc1[C@@]1(C(=O)NO)C=C(c2cc(F)cnc2C2CC2)CC1>>Cc1c(F)cccc1[C@]1(C(=O)NO)CC[C@@H](c2cc(F)cnc2C2CC2)C1,[Pd],CO,,,,test
US20060247263A1,CC(C)(C)OC(=O)N1CCC(N)CC1.CN(c1cc(-c2ccccc2)c2ncn(C)c2c1)c1ccnc(S(C)=O)n1>>CN(c1cc(-c2ccccc2)c2ncn(C)c2c1)c1ccnc(NC2CCN(C(=O)OC(C)(C)C)CC2)n1,,C1COCCO1,,,,test
US20130115190A1,COc1ccc2c(c1)NC(c1ccc(OC(C)C)cc1)N=C2O>>COc1ccc2c(O)nc(-c3ccc(OC(C)C)cc3)nc2c1,,ClCCl,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20050032871A1,Cc1[nH]c(C=O)c(CCC(=O)O)c1S(C)(=O)=O.O=C1Cc2ccc(Br)cc2N1>>Cc1[nH]c(/C=C2\C(=O)Nc3cc(Br)ccc32)c(CCC(=O)O)c1S(C)(=O)=O,,CCO,,C1CCNCC1,,test
US20030114666A1,CC(C)(C)OC(=O)N[C@H]1CCN(c2nc3c(cc2F)c(=O)[nH]c(=O)n3C2CC2)C1.Cl>>Cl.N[C@H]1CCN(c2nc3c(cc2F)c(=O)[nH]c(=O)n3C2CC2)C1,,CCO,,,,test
US20050148656A1,CC(C)c1ccc(CNCc2ccc(Cl)cc2)cc1.CCOC(=O)[C@H](Cc1ccc(OCC(=O)O)cc1)OCC>>CCOC(=O)[C@H](Cc1ccc(OCC(=O)N(Cc2ccc(Cl)cc2)Cc2ccc(C(C)C)cc2)cc1)OCC,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20040110741A1,C1CNCCN1.NC(=O)c1nn(-c2ccc3c(c2)OCO3)c2c1CCc1ccc(NC(=O)c3cc(Cl)ncc3Cl)cc1-2>>NC(=O)c1nn(-c2ccc3c(c2)OCO3)c2c1CCc1ccc(NC(=O)c3cc(N4CCNCC4)ncc3Cl)cc1-2,,CCO,,,,test
US20040254158A1,CC(C)(CN1CCOCC1)c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1>>CC(C)(CN1CCOCC1)c1ccc(-c2nc3ccc(Cl)cc3c(=O)n2-c2ccc(Cl)cn2)cc1,,C1COCCO1,Cl,C1CCOC1,,test
US20140005146A1,CO.NC(=O)c1cnn2cc(Br)cc2c1Cl>>COc1c(C(N)=O)cnn2cc(Br)cc12,,CO,,C[O-].[Na+],,test
US20020072518A1,CCOC(=O)CN1CCc2cc(OC)ccc2C1=O>>CCOC(=O)CN1CCc2cc(O)ccc2C1=O,,ClCCl,,BrB(Br)Br,,test
US20130053370A1,Cc1ccc(C(=O)O)cc1/C=C/c1csc2c(N)ncnc12.Nc1cccc(C(F)(F)F)c1>>Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1/C=C/c1csc2c(N)ncnc12,,CCOC(C)=O,CN(C)C=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US04007202,C=C(C)C(C(=O)OC(c1ccccc1)c1ccccc1)N1C(=O)C(NC(=O)COc2ccccc2)C1SN1C(=O)c2ccccc2C1=O.O=C1CCC(=O)N1Br>>C=C(CBr)C(C(=O)OC(c1ccccc1)c1ccccc1)N1C(=O)C(NC(=O)COc2ccccc2)C1SN1C(=O)c2ccccc2C1=O,,ClCCCl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20100009975A1,CN(CCN1CCSc2ccc([N+](=O)[O-])cc21)C(=O)OC(C)(C)C.CSC(=N)c1cccs1>>CN(CCN1CCSc2ccc(NC(=N)c3cccs3)cc21)C(=O)OC(C)(C)C,[Pd],CCO,,I,,test
US20070203139A1,CI.COc1c(C#N)cc2ccccc2c1CN(C)C(=O)C(c1ccc(F)cc1)N1CC[C@@H](NC(=O)OC(C)(C)C)C1>>COc1c(C#N)cc2ccccc2c1CN(C)C(=O)C(c1ccc(F)cc1)N1CC[C@@H](N(C)C(=O)OC(C)(C)C)C1,,CN(C)C=O,,[H-].[Na+],,test
US20070129346A1,CC(=O)OCC(C)(C)C(=O)Cl.O=C(OCc1ccccc1)N1CC[C@H](NC2CCCCC2)C1>>CC(=O)OCC(C)(C)C(=O)N(C1CCCCC1)[C@H]1CCN(C(=O)OCc2ccccc2)C1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20070049612A1,O=S(=O)(c1ccc(Cl)cc1)N1C2CCCC1c1nnn(S(=O)(=O)c3ccc(Cl)cc3)c1C2>>O=S(=O)(c1ccc(Cl)cc1)N1C2CCCC1c1nn[nH]c1C2,,C1CCOC1,O,[Na+].[OH-],,test
US20080312316A1,BrCCCBr.CC(C)c1oc2c(O)c(NC=O)ccc2c(=O)c1-c1ccc(Cl)cc1>>CC(C)c1oc2c3c(ccc2c(=O)c1-c1ccc(Cl)cc1)N(C=O)CCCO3,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110263604A1,O=[N+]([O-])[C@H]1C[C@@H]1c1ccc(OCc2ccccc2)cc1>>N[C@@H]1C[C@H]1c1ccc(OCc2ccccc2)cc1,[Zn],CC(C)O,,Cl,,test
US20100240678A1,CCOC(=O)CCCOc1cccc(CCCCCCOc2cc(Br)cc(COC)c2)c1CCC(=O)OCC>>COCc1cc(Br)cc(OCCCCCCc2cccc(OCCCC(=O)O)c2CCC(=O)O)c1,,CCO,CCOC(C)=O,[Na+].[OH-],,test
US06177424B1,Cc1cc(=O)oc2c(C)c(O)ccc12.O=[N+]([O-])O>>Cc1cc(=O)oc2c(C)c(O)c([N+](=O)[O-])cc12,,O=S(=O)(O)O,,,,test
US20140364414A1,COCCOCCBr.Oc1ccc(Br)cc1>>COCCOCCOc1ccc(Br)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20100210694A1,CC(=O)Oc1ccccc1C(=O)OCCl.O=C(O)c1ccc(CC(CO[N+](=O)[O-])O[N+](=O)[O-])cc1>>CC(=O)Oc1ccccc1C(=O)OCOC(=O)c1ccc(CC(CO[N+](=O)[O-])O[N+](=O)[O-])cc1,,CN(C)C=O,O,CCN(CC)CC,,test
US06420362B1,CON=C(C)C(C)=NN.CON=C(C1=NOCCO1)c1ccccc1C=O>>CON=C(C)C(C)=NN=Cc1ccccc1C(=NOC)C1=NOCCO1,,CCO,,,,test
US20030105099A1,O=C(CC(CC1CCCCC1)C(=O)N1C(=O)OCC1Cc1ccccc1)N1CCOCC1.OO>>O=C(O)C(CC(=O)N1CCOCC1)CC1CCCCC1,,C1CCOC1,O,[Li+].[OH-],,test
US20150274704A1,CS(=O)(=O)Cl.Cn1cc(Nc2ncc(Cl)c(NC3CCC4(CCNCC4)CC3)n2)cn1>>Cn1cc(Nc2ncc(Cl)c(NC3CCC4(CC3)CCN(S(C)(=O)=O)CC4)n2)cn1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20110105447A1,CN(C)C=O.Cc1ncsc1C(=O)O.ClCCl>>CCOC(=O)c1scnc1C,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20020193599A1,C=C1CC(=O)O1.NCCCBr>>CC(=O)CC(=O)NCCCBr,,C1CCOC1,,Br,CCN(CC)CC,test
US20150164974A1,CC(C)(C)OC(=O)N1C[Si](C)(C)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21.O=C(O)C(F)(F)F>>C[Si]1(C)CN[C@H](C(=O)N[C@@H]2CCCc3ccccc32)C1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20030208079A1,COC(Cl)Cl.COc1ccc2c(c1)COC2C(F)(F)F>>COc1cc2c(cc1C=O)C(C(F)(F)F)OC2,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20030119803A1,CO.C[Si](C)(C)Cl.Cl.NCCCC[C@H](N)C(=O)O>>CO.COC(=O)[C@@H](N)CCCCN.Cl.Cl,,CO,,,,test
US20090111800A1,Nc1ccc2cn[nH]c2c1>>NC1CCc2cn[nH]c2C1,[Rh],CCO,,,,test
US20160060241A1,COc1cc2c(c(OC)c1OC)CCC(=O)O2.COc1ccc(C=O)cc1O>>COc1ccc(/C=C2\COc3cc(OC)c(OC)c(OC)c3C2=O)cc1O,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20070244132A1,CC(C)(O)CC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(C(F)(F)F)c4)c(Cl)c3)c21.CS(=O)(=O)O>>CC(C)(O)CC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(C(F)(F)F)c4)c(Cl)c3)c21.CS(=O)(=O)O,,CCOC(C)=O,,,,test
US20050250836A1,C=O.CNC.Cn1ccc2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O>>CN(C)Cc1cn(C)c2cc(-c3ccccc3Cl)c3c(c12)C(=O)NC3=O,,C1CCOC1,CC(=O)O,,,test
US20120142625A1,COCC(C)(C)c1ccc(N=[N+]=[N-])c([N+](=O)[O-])c1>>COCC(C)(C)c1ccc(N)c(N)c1,[Pd],CCO,,,,test
US20090186912A1,CS(=O)(=O)Cl.Nc1ccc(Cl)c([N+](=O)[O-])c1>>CS(=O)(=O)Nc1ccc(Cl)c([N+](=O)[O-])c1,,C1CCOC1,Cl,c1ccncc1,,test
US20070244169A1,CC(C)Cc1ccc2[nH]nc(NC(N)=S)c2c1.CCOC(CBr)OCC>>CC(C)Cc1ccc2[nH]nc(Nc3nccs3)c2c1,,CCO,Cl,,,test
US20140275111A1,CCOc1cc(-c2ccc(CC(=O)Nc3cnc(C(C)(C)O)c(C(F)(F)F)c3)c(F)c2)cnc1OCc1ccc(OC)cc1>>CCOc1cc(-c2ccc(CC(=O)Nc3cnc(C(C)(C)O)c(C(F)(F)F)c3)c(F)c2)c[nH]c1=O,[Pd],CO,,,,test
US20090240058A1,CCOC(=O)C(C)(C)Oc1ccc(C(=O)CCc2cc(-c3ccc(C(F)(F)F)cc3)nn2C(C)C)cc1C>>Cc1cc(C(=O)CCc2cc(-c3ccc(C(F)(F)F)cc3)nn2C(C)C)ccc1OC(C)(C)C(=O)O,,C1CCOC1,CCO,[Na+].[OH-],,test
US20080096861A1,CC(C)(C)OC(=O)N1CCC(CCl)CC1.CC(C)(C)OC(=O)N1CCCCC1CCO>>CC(C)(C)OC(=O)N1CCCCC1CCCl,,ClC(Cl)(Cl)Cl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070043028A1,CCOC(=O)C1CCN(C(=O)c2cccc([C@H](c3cccc(O)c3)N3C[C@@H](C)NC[C@@H]3C)c2)CC1.O=Cc1cccc(F)c1>>CCOC(=O)C1CCN(C(=O)c2cccc([C@H](c3cccc(O)c3)N3C[C@@H](C)N(Cc4cccc(F)c4)C[C@@H]3C)c2)CC1,,CN(C)C=O,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160214932A1,Fc1cc(Cl)c(SCC(F)(F)F)cc1OCCCCCSC(F)(F)F.O=C(OO)c1cccc(Cl)c1>>O=S(CC(F)(F)F)c1cc(OCCCCCSC(F)(F)F)c(F)cc1Cl,,ClC(Cl)Cl,,CCCCCC,CCOC(C)=O,test
US20100130470A1,CC(=O)OC(C)=O.Cc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)CNCCN3)oc2ccccc12>>CC(=O)N1CCNc2ncc(/C=C/C(=O)N(C)Cc3oc4ccccc4c3C)cc2C1,,ClCCl,,CCN(CC)CC,,test
US04271163,O=C1OC(=O)C2CC12.c1ccc(-c2ccccc2)cc1>>O=C(O)[C@@H]1C[C@@H]1C(=O)c1ccccc1-c1ccccc1,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20110212053A1,CC(C)(C#N)c1ccc(C(=NO)c2c(O)cnc3ccc(Br)cc23)cc1>>CC(C)(C#N)c1ccc(-c2noc3cnc4ccc(Br)cc4c23)cc1,,CC(=O)O,,O,,test
US20100130496A1,Nc1ccc2c(c1)CNCC2.O=C(Cl)OCc1ccccc1>>Nc1ccc2c(c1)CN(C(=O)OCc1ccccc1)CC2,,ClCCl,,CCN(CC)CC,,test
US03983111,BrBr.CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4[C@@H](Br)[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C>>C[C@]12CC[C@@H](O)[C@H](Br)[C@@H]1CC[C@@H]1[C@@H]2C(=O)C[C@]2(C)[C@@H](C(=O)CBr)CC[C@@H]12,,CO,O,,,test
US20010021718A1,CC(C)(C)OC(=O)N1CC(NC(=O)c2noc([C@H](CCCC3CCCCC3)CC(=O)O)n2)C1.C[Si](C)(C)ON>>CC(C)(C)OC(=O)N1CC(NC(=O)c2noc([C@H](CCCC3CCCCC3)CC(=O)NO)n2)C1,,C1CCOC1,CO,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20050187223A1,CS(=O)(=O)c1nccc(N2CCCn3c2nc(-c2ccccc2)c([N+](=O)[O-])c3=O)n1.NCCc1ccccc1>>O=c1c([N+](=O)[O-])c(-c2ccccc2)nc2n1CCCN2c1ccnc(NCCc2ccccc2)n1,,ClCCl,,,,test
US20150252038A1,CC(C)(C)OC(=O)c1cc(C2CC2)c(OCC2CN(C(=O)OC(C)(C)C)C2)cc1F>>CC(C)(C)OC(=O)N1CC(COc2cc(F)c(C(=O)O)cc2C2CC2)C1,,CO,O,Cl,[K+].[OH-],test
US20090291937A1,C1CCOC1.O=CC1(c2cccc(Br)c2)CCN(C(=O)OCc2ccccc2)C1>>C=CC1(c2cccc(Br)c2)CCN(C(=O)OCc2ccccc2)C1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20080207654A1,CCCCc1nc(C)c(C(O)c2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nc(C)c(C(O)c2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,O,,CS(C)=O,[Cl-].[Na+],test
US05744426,CCOC(=O)CC(=O)c1cc(C)c(Cl)cc1Cl.CNN>>Cc1cc(C2=NN(C)C(=O)C2)c(Cl)cc1Cl,,CCOCC,,,,test
US20110251169A1,CC(C)(C)C(=O)CN(Cc1ccccc1)Cc1ccccc1.C[Mg]Br>>CC(C)(C)C(C)(O)CN(Cc1ccccc1)Cc1ccccc1,,CCOCC,,,,test
US20150225396A1,CC(C)(C)OC(=O)CCBr.O=c1[nH]c(S)nc2ccccc12>>CC(C)(C)OC(=O)CCSc1nc2ccccc2c(=O)[nH]1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05840912,Cn1nc(N2CC(C#N)(C=O)C=N2)c(Cl)c1OC(F)F.OCCO>>Cn1nc(-n2ncc(C#N)c2C2OCCO2)c(Cl)c1OC(F)F,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100136142A1,CC1=C(C(=O)OCCC#N)C(c2cccc3c(=O)cc(C)oc23)c2c(c(C)c[nH]c2=O)N1.CCOC(OCC)OCC>>CCOc1ncc(C)c2c1C(c1cccc3c(=O)cc(C)oc13)C(C(=O)OCCC#N)=C(C)N2,O=S(=O)(O)O,CN(C)C=O,,,,test
US20090176823A1,CC1(C)OB(c2ccc(OCc3cc(-c4c(F)ccc(F)c4Cl)no3)nc2)OC1(C)C.COC(=O)C1=C(OS(=O)(=O)C(F)(F)F)CCN(C(=O)OC(C)(C)C)C1>>COC(=O)C1=C(c2ccc(OCc3cc(-c4c(F)ccc(F)c4Cl)no3)nc2)CCN(C(=O)OC(C)(C)C)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US20080090822A1,CS(=O)(=O)c1ccc(N2CCCCC2)c(C(=O)N2CCN(c3ccc([N+](=O)[O-])cn3)CC2)c1>>CS(=O)(=O)c1ccc(N2CCCCC2)c(C(=O)N2CCN(c3ccc(N)cn3)CC2)c1,[Pd],CCO,ClCCl,,,test
US20140336377A1,COC(=O)c1cc(C)nc(NC(C)=O)c1>>CC(=O)Nc1cc(C(=O)O)cc(C)n1,,C1CCOC1,,Cl,[Na+].[OH-],test
US04006145,FC(F)(F)c1ccc(Sc2ccccc2)c(CCl)c1.[C-]#N>>N#CCc1cc(C(F)(F)F)ccc1Sc1ccccc1,,CS(C)=O,,O,,test
US06420381B1,CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cc(CBr)cc2C(C)C)c(-c2cccc(OC)c2)c2cccnc21.O=C1NC(=O)c2ccccc21>>CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cc(CN)cc2C(C)C)c(-c2cccc(OC)c2)c2cccnc21,,CN(C)C=O,,O,[K],test
US20130253204A1,CC(C)(C)OC(=O)N1OC1C(Cl)(Cl)Cl.NC1(Cc2ccccc2)CC1>>CC(C)(C)OC(=O)NNC1(Cc2ccccc2)CC1,,ClCCl,,,,test
US20070105904A1,N#Cc1cccc(CBr)c1.Nc1ccc(-c2cc(Cc3ccc(O)cc3)no2)c(N)n1>>N#Cc1cccc(COc2ccc(Cc3cc(-c4ccc(N)nc4N)on3)cc2)c1,,CN(C)C=O,,CO,[Na+].[OH-],test
US20130261123A1,O=C(O)c1ccc(B(O)O)c(Cl)c1.Oc1ccc2nc(Cl)ccc2c1F>>O=C(O)c1ccc(-c2ccc3c(F)c(O)ccc3n2)c(Cl)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])O.[Na+],,test
US05646173,CC=CCC1Cc2ccc(C(=O)OC)cc2C1=O.O=[O+][O-]>>COC(=O)c1ccc2c(c1)C(=O)C(CC=O)C2,,ClCCl,,,,test
US05229519,C=CC#N.O=CC1CC2C=CC1C2>>N#CCCC12C=CC(CC1C=O)C2,,Cc1ccccc1,,[K+].[OH-],,test
US20160257657A1,COC(=O)CSc1ccccc1>>O=C(O)CSc1ccccc1,,CO,,[Li+].[OH-],,test
US20150315146A1,C1CCOC1.CC12CCC(C1)C(C)(C)C2=O>>C#CC1(O)C2(C)CCC(C2)C1(C)C,,O,,,,test
US20150105369A1,Br[Mg]C1CC1.Cn1cncc1C(=O)c1ccc2nc(Cl)c(-c3ccccc3)c(Cl)c2c1>>Cn1cncc1C(O)(c1ccc2nc(Cl)c(-c3ccccc3)c(Cl)c2c1)C1CC1,,C1CCOC1,,,,test
US20140080816A1,O=C1Nc2ccccc2N2CCCCCC12>>c1ccc2c(c1)NCC1CCCCCN21,,C1CCOC1,,Cl,,test
US04568741,O=C(Cl)Cl.O=CN1CCCCC1>>ClC=[N+]1CCCCC1.[Cl-],,CCOCC,,,,test
US20110230490A1,Nc1cnc2cccnn12.O=C(Cl)Oc1ccccc1>>O=C(Nc1cnc2cccnn12)Oc1ccccc1,,CCOC(C)=O,CN(C)C=O,c1ccncc1,,test
US20100227864A1,C[Si](C)(C)c1[nH]nc(C#N)c1-c1cccs1>>N#Cc1n[nH]cc1-c1cccs1,,CO,,Cl,[Na+].[OH-],test
US20060046990A1,COc1cc(N2CCC(N3CCCC3)CC2)ccc1[N+](=O)[O-]>>COc1cc(N2CCC(N3CCCC3)CC2)ccc1N,[Ni],C1CCOC1,,[H][H],,test
US05925631,CS(=O)(=O)c1ccc(C2=C(Oc3ccccc3)C(=O)CC2)cc1>>CSc1ccc(C2=C(Oc3ccccc3)C(=O)CC2)cc1,,CO,,C1CCC2=NCCCN2CC1,,test
US05455258,COc1ccc(S(=O)(=O)N(Cc2ccccc2)C2(C(=O)NOC(C)(C)C)CCN(Cc3ccccc3)CC2)cc1>>COc1ccc(S(=O)(=O)N(Cc2ccccc2)C2(C(=O)NO)CCN(Cc3ccccc3)CC2)cc1,,CC(Cl)Cl,,CCO,,test
US20150051201A1,O=C(O)[C@@H]1CCCN1.O=C(OC(=O)C(F)(F)F)C(F)(F)F.O=N[O-]>>O=C([O-])N1OC(O)C2=[N+]1CCC2,,O,,Cl,,test
US20030139393A1,O=[N+]([O-])O.O=c1ccc2c([nH]1)CCCC2>>O=c1[nH]c2c(cc1[N+](=O)[O-])CCCC2,,O=S(=O)(O)O,,,,test
US04826990,Nc1cccc(OCc2csc(-c3ccccc3)n2)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=S(=O)(Nc1cccc(OCc2csc(-c3ccccc3)n2)c1)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20090209522A1,BrBr.CC(C)(C)c1cccc(O)c1>>CC(C)(C)c1ccc(Br)c(O)c1,,ClC(Cl)(Cl)Cl,,ClCCl,O,test
US20110034441A1,CN(C)C=O.O=C(O)c1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1>>CN(C)C(=O)c1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20090023707A1,CCOC(=O)c1coc(-c2ccc(CO)cc2)n1.O=S(Cl)Cl>>CCOC(=O)c1coc(-c2ccc(CCl)cc2)n1,,ClCCl,,,,test
US20020128232A1,C=CCN=C=O.Oc1nc2ccccc2[nH]1>>C=CCNC(=O)n1c(=O)[nH]c2ccccc21,,CN(C)C=O,,,,test
US20090286801A1,CCOC(=O)Cl.Nc1cccc(N2CCN(CCC3CCC4(CC3)OCCO4)CC2)c1>>CCOC(=O)Nc1cccc(N2CCN(CCC3CCC4(CC3)OCCO4)CC2)c1,,ClCCl,,CCN(CC)CC,,test
US20150299178A1,CC(=O)N(c1nc(Br)cs1)C1CC1.OB(O)c1ccc(Cl)cc1>>CC(=O)N(c1nc(-c2ccc(Cl)cc2)cs1)C1CC1,,Cc1ccccc1,,CCO,O=C([O-])[O-].[K+].[K+],test
US20100256097A1,Brc1cccc(Cn2ccnn2)n1.OCn1nnc2ccccc21>>OCC(c1cccc(Br)n1)n1ccnn1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20110028448A1,CC(C)O.Cc1cc(C(=O)O)cnc1Cl>>Cc1cc(C(=O)OC(C)C)cnc1Cl,,CCOCC,,C[Si](C)(C)Cl,,test
US20150166565A1,CCOC(=O)Cc1nc(N(C)C2CC2)c2c3c(sc2n1)CCCCC3>>CN(c1nc(CC(=O)O)nc2sc3c(c12)CCCCC3)C1CC1,,C1CCOC1,Cl,O,[Li+].[OH-],test
US20110311474A1,CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCC1=O.CCOP(=O)(Cl)OCC>>CCOC(=O)C1=C(OP(=O)(OCC)OCC)CCN(C(=O)OC(C)(C)C)C1,,COC(C)(C)C,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20060106034A1,CC(C)c1csc(CCc2ccn3c(=O)c(/C=C/C(=O)OC(C)(C)C)c(O)nc3c2)n1>>C=C(C(=O)O)c1c(O)nc2cc(CCc3nc(C(C)C)cs3)ccn2c1=O,,Cc1ccccc1,,O=CO,,test
US20060160877A1,COC(=O)c1cc2cccc(-c3ccc(N4CCOCC4)cc3)c2s1>>O=C(O)c1cc2cccc(-c3ccc(N4CCOCC4)cc3)c2s1,,CO,,[K+].[OH-],,test
US05885990,CN(C)C=O.COC(=O)Cc1c(O)ccc2cc(Br)ccc12>>N#Cc1ccc2c(CC(=O)O)c(O)ccc2c1,,O,,,,test
US20040044052A1,CCCCOC(=O)[C@H]1CN(c2ccc3c(c2)sc(=O)n3C)C(=O)O1.NCCO>>Cn1c(=O)sc2cc(N3C[C@H](C(=O)NCCO)OC3=O)ccc21,,CC#N,,,,test
US20070037836A1,CN(C)c1nc(Nc2ccc(NC(=O)OC(C)(C)C)cc2)nc2ccccc12.O=S(=O)(Cl)c1ccc(Br)cc1OC(F)(F)F>>CN(C)c1nc(Nc2ccc(NS(=O)(=O)c3ccc(Br)cc3OC(F)(F)F)cc2)nc2ccccc12,,CCOC(C)=O,ClCCl,Cl,O=C([O-])O.[Na+],test
US05589478,C=C(OCC)c1cnc(OCCOc2ncnc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)c2Oc2cccc(OC)c2)nc1>>COc1cccc(Oc2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)ncnc2OCCOc2ncc(C(C)=O)cn2)c1,,CC(C)=O,,Cl,O=C([O-])O.[Na+],test
US20150353570A1,Nc1nccn2c([C@@H]3CC[C@@H]4COCC(=O)N4C3)nc(Br)c12.O=C=O>>O=C(O)[C@H]1CC[C@@H]2CCC(=O)N2C1,,CO,,,,test
US20140171403A1,CC(C)(C)C(=O)OCn1cc(CCCC(=O)NC2CCN(C(=O)/C=C/c3cc(Cl)cc(Cl)c3)CC2)nn1>>O=C(CCCc1c[nH]nn1)NC1CCN(C(=O)/C=C/c2cc(Cl)cc(Cl)c2)CC1,,CO,,Cl,[Na+].[OH-],test
US06656737B1,C1CNCCN1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.OCc1c2ccccc2cc2ccccc12>>O=C(OCc1c2ccccc2cc2ccccc12)N1CCNCC1,,O,,c1ccncc1,,test
US20100286191A1,COC(=O)c1cc(C(C)(C)C)c2c(c1)C(C)(C)CCO2>>CC(C)(C)c1cc(C(=O)O)cc2c1OCCC2(C)C,,CO,,C1CCOC1,[Na+].[OH-],test
US20160235716A1,CC(C)(C)OC(=O)CBr.N#Cc1cccc2c1CCC21NC(=O)NC1=O>>CC(C)(C)OC(=O)CN1C(=O)NC2(CCc3c(C#N)cccc32)C1=O,,O,,O=C([O-])[O-].[K+].[K+],,test
US20160024056A1,O=S(=O)(c1ccc(Cl)cc1)N1CCC(Cn2ccc3cc(-c4cnn(C5CCCCO5)c4)ccc32)CC1>>O=S(=O)(c1ccc(Cl)cc1)N1CCC(Cn2ccc3cc(-c4cn[nH]c4)ccc32)CC1,,CO,ClCCl,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20030004172A1,Cn1c(=O)[nH]c(=O)c2sc(C(=O)O)cc21.NCc1ccccc1>>Cn1c(=O)[nH]c(=O)c2sc(C(=O)NCc3ccccc3)cc21,,CCO,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US07071201B2,O=C1C(=O)N(C2CCN(CCc3ccc(F)cc3)CC2)c2cc(Br)ccc21>>Fc1ccc(CCN2CCC(Nc3cccc(Br)c3)CC2)cc1,,C1CCOC1,,CCOC(C)=O,O=C([O-])O.[Na+],test
US20130131094A1,NCC(=O)O.O=C(Cl)c1cccs1>>O=C(O)CNC(=O)c1cccs1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20140227444A1,CC(C)(C)N=CC(=O)C(C)(C)C.[Li]C(C)(C)C>>CC(C)(C)N=CC(O)(C(C)(C)C)C(C)(C)C,,CCOCC,,,,test
US06399603B1,Nc1ccc(Cl)c(Cl)c1.Oc1nc(Cl)nc2c(Br)cccc12>>Oc1nc(Nc2ccc(Cl)c(Cl)c2)nc2c(Br)cccc12,,CN1CCCC1=O,,,,test
US20080132459A1,COc1ccc(NCc2ccc(C(=O)O)cc2)cc1OC.Nc1cccc(-c2cccs2)c1>>COc1ccc(NCc2ccc(C(=O)Nc3cccc(-c4cccs4)c3)cc2)cc1OC,,CN(C)C=O,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US20040048882A1,CSc1nnc(C(N)(c2ccc(Cl)cc2)c2ccc3c(c2)c(-c2cccc(Cl)c2)nc2nnnn23)n1C>>Cn1cnnc1C(N)(c1ccc(Cl)cc1)c1ccc2c(c1)c(-c1cccc(Cl)c1)nc1nnnn12,[Ni],CC(C)=O,,,,test
US20110166132A1,Cc1cc(-c2ccc(NC(=O)C(C)c3cccc(Cl)n3)cc2)ccn1.OB(O)c1ccc(N2CCOCC2)cc1>>Cc1cc(-c2ccc(NC(=O)C(C)c3cccc(-c4ccc(N5CCOCC5)cc4)n3)cc2)ccn1,,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20090318456A1,CI.Oc1nc(S)nc2ncc(-c3ccc(F)cc3)nc12>>CSc1nc(O)c2nc(-c3ccc(F)cc3)cnc2n1,,CN(C)C=O,,O,,test
US20090264416A1,CC(C)(C)NC(=O)c1cccc(CN2CCN(C(=O)c3ccc(N)cc3)CC2)c1.Nc1ccon1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)(C)NC(=O)c1cccc(CN2CCN(C(=O)c3ccc(NC(=O)Nc4ccon4)cc3)CC2)c1,,ClCCl,,,,test
US06218405B1,CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1.CC(C)(C)OC(=O)N1CCC(CN)CC1>>CC(=O)NC1(CNS(=O)(=O)c2ccccc2)CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,CCN(CC)CC,O,test
US20130053364A1,CCCC[Sn](/C=C\CO)(CCCC)CCCC.COC(=O)c1c(CS(=O)(=O)c2ccccc2Br)ccc(Br)c1OC>>COC(=O)c1c(CS(=O)(=O)c2ccccc2C=CCO)ccc(Br)c1OC,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,Cc1ccccc1,,,,test
US06537948B1,Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3cnccc3OCc3ccccc3)c([N+](=O)[O-])cc2F)c1=O>>Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3cnccc3OCc3ccccc3)c(N)cc2F)c1=O,[Fe],CC(=O)O,CCOC(C)=O,O,,test
US04551460,OCCCCC#Cc1ccsc1>>OCCCCCCc1ccsc1,[Pd],CCO,,,,test
US04997840,Cn1cc(OC(=O)c2ccccc2)c(=O)c2cccc(F)c21>>Cn1cc(O)c(=O)c2cccc(F)c21,,ClCCl,,C1CCNCC1,,test
US20100160434A1,C#CCCCCCCOS(=O)(=O)c1ccc(C)cc1.N#CCS(=O)(=O)CCC(F)(F)F>>C#CCCCCCCC(C#N)S(=O)(=O)CCC(F)(F)F,,CS(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20130065861A1,CC(C)(C)O.CC(C)(C)OC(=O)[C@H](CS)NC(=O)OCc1ccccc1.O=C([O-])c1ccccc1[N+](=O)[O-]>>CC(C)(C)OC(=O)[C@H](CSC[C@H](O)CO)NC(=O)OCc1ccccc1,,CC(C)(C)O,,[Na+].[OH-],,test
US20100004289A1,COc1cccc([Mg]Br)c1.O=C(Cl)CCCCl>>COc1cccc(C(=O)CCCCl)c1,,C1CCOC1,,,,test
US20120202814A1,Nc1ccccc1[N+](=O)[O-].O=C(O)CCN1C(=O)CSC1=S>>O=C(CCN1C(=O)CSC1=S)Nc1ccccc1[N+](=O)[O-],,ClCCl,,O,O=S(Cl)Cl,test
US04833270,O=C(Cl)C(=O)Cl.O=C(O)c1cc(F)c(F)cc1Cl>>O=C(Cl)c1cc(F)c(F)cc1Cl,,CC#N,,CN(C)C=O,,test
US06143747,ClCI.O=CCCc1ccccc1N(Cc1ccccc1)Cc1ccccc1>>c1ccc(C[C@@H]([C@H]2CO2)N(Cc2ccccc2)Cc2ccccc2)cc1,,CCCCCC,CCOC(C)=O,C1CCOC1,[Li]CCCC,test
US06518268B1,Nc1ccc(C(=O)Nc2cccc(C=C3SC(=O)NC3=O)c2)cc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=C1NC(=O)C(=Cc2cccc(NC(=O)c3ccc(NS(=O)(=O)c4ccc(Cl)cc4)cc3)c2)S1,,CCOC(C)=O,c1ccncc1,CCCCCC,,test
US20060030613A1,CC(C)(C)c1ccc(C(=O)NCCc2cccc(C(F)(F)F)c2)c(Cl)c1>>CC(C)(C)c1ccc(CNCCc2cccc(C(F)(F)F)c2)c(Cl)c1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20110190278A1,CC(C)(Br)C(=O)Br.COC(=O)c1cc(N)c(O)cc1C(F)(F)F>>COC(=O)c1cc(NC(=O)C(C)(C)Br)c(O)cc1C(F)(F)F,,C1CCOC1,ClC(Cl)Cl,O=C([O-])O.[Na+],,test
US20110288097A1,CC(C)(C)OC(=O)N1CCC(NC(=O)c2cn(COCC[Si](C)(C)C)c3ncc(C4CC4)nc23)(C(C)(C)O)C1>>CC(C)(O)C1(NC(=O)c2c[nH]c3ncc(C4CC4)nc23)CCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05486603,C[C@]12CCC(=O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12.[NH4+]>>C[C@]12CC[C@H](N)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12,,CO,,[BH3-]C#N.[Na+],,test
US05932590,CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCc1cncn1Cc1ccc(C#N)cc1.Cl>>Cl.N#Cc1ccc(Cn2cncc2CCNC(=O)[C@@H]2Cc3ccccc3CN2)cc1,,CCOC(C)=O,,,,test
US20090182007A1,CC(C)(O)C(c1cccc(Cl)c1C#N)n1cncc1CO[Si](C)(C)C(C)(C)C.O=S(=O)(O)O>>CC1(C)OC(=O)c2c(Cl)cccc2C1n1cncc1CO,,C1COCCO1,O,O=C([O-])O.[Na+],,test
US04692184,CCOC(=O)C1=C(C(F)(F)F)NC(C(F)(F)F)=C(C(=O)OCC)C1CC(C)C>>CCOC(=O)c1c(C(F)F)nc(C(F)(F)F)c(C(=O)OCC)c1CC(C)C,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20120061620A1,C=CCBr.CC(C)[SiH](CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(C(F)(F)F)C(F)(F)F)C(C)C>>CC(C)[Si](Br)(CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(C(F)(F)F)C(F)(F)F)C(C)C,Cl[Pd]Cl,c1ccccc1,,,,test
US20140045862A1,C1=COCCC1.c1ccc(CO[C@H]2CCC[C@@H]2c2ccn[nH]2)cc1>>c1ccc(CO[C@H]2CCC[C@@H]2c2ccn(C3CCCCO3)n2)cc1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05508408,C=[N+]=[N-].CCC(CC)(CC(=O)Nc1cccc(OCc2ccc3ccc(F)cc3n2)c1)C(=O)O>>CCC(CC)(CC(=O)Nc1cccc(OCc2ccc3ccc(F)cc3n2)c1)C(=O)OC,,C1CCOC1,CCOCC,,,test
US20100016282A1,C[C@@H]1NCCN(CCCO)C1=O.O=C(Cl)OCc1ccccc1>>C[C@H]1C(=O)N(CCCO)CCN1C(=O)OCc1ccccc1,,CC(C)=O,O,O=C([O-])O.[Na+],,test
US20150152118A1,N#C[Zn]C#N.O=c1[nH]c(C2=C[C@H](N3CCN(c4ccc(I)cc4F)CC3)CC2)nc2c1CC1(CC2)CC1>>N#Cc1ccc(N2CCN([C@H]3C=C(c4nc5c(c(=O)[nH]4)CC4(CC5)CC4)CC3)CC2)c(F)c1,,CN(C)C=O,,,,test
US20140187553A1,COc1ccc(CN)cc1.Cc1ccc(S(=O)(=O)n2cc(I)c3cc(-c4nnc(S(C)=O)s4)ccc32)cc1>>COc1ccc(CNc2nnc(-c3ccc4c(c3)c(I)cn4S(=O)(=O)c3ccc(C)cc3)s2)cc1,,C1COCCO1,,,,test
US20080280948A1,CC(=O)C(Cl)Cc1cccc(Cl)c1.COc1cc(NC(N)=S)ccc1-n1cnc(C)c1>>COc1cc(Nc2nc(C)c(Cc3cccc(Cl)c3)s2)ccc1-n1cnc(C)c1,,CCO,,,,test
US20090275592A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(C(F)(F)F)nc1)C(=O)C1C(=O)OC(C)(C)OC1=O>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(C(F)(F)F)nc1)CC1C(=O)OC(C)(C)OC1=O,,ClCCl,,CC(=O)O,[BH4-].[Na+],test
US04223038,O=C1NC2CC=CCC12.O=CC(=O)OCc1ccccc1>>O=C(OCc1ccccc1)C(O)N1C(=O)C2CC=CCC21,,c1ccccc1,,O,,test
US05208247,CC(=O)NCc1ccccn1.CCCCCCCCCCCCCCOc1ccc(C(=O)Cl)cc1C(C)(C)C>>CCCCCCCCCCCCCCOc1ccc(C(=O)N(Cc2ccccn2)C(C)=O)cc1C(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US05097013,CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)O>>CC(C)C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)O,,CS(C)=O,,C1CCNCC1,CC(=O)O,test
US05972965,COc1cccc2c1CCCC2NC(C)c1nc(-c2ccccc2)c(-c2ccccc2)o1>>CC(NC1CCCc2c(O)cccc21)c1nc(-c2ccccc2)c(-c2ccccc2)o1,,ClCCl,,BrB(Br)Br,,test
US20090264650A1,O=C(O)C1(Cc2ccccc2[N+](=O)[O-])CCN(C2CCCCC2)C1=O>>O=C1C(Cc2ccccc2[N+](=O)[O-])CCN1C1CCCCC1,,C1COCCO1,,,,test
US05089496,CN1CCC(C(=O)c2ncccc2CCc2ccccc2)CC1>>CN1CCC(C(O)c2ncccc2CCc2ccccc2)CC1,,CO,O,[BH4-].[Na+],,test
US20140080798A1,CC(C)(C)OC(=O)N(CCO)Cc1ccc(Nc2ncc(C(F)(F)F)c(CCc3ccccc3CC(N)=O)n2)cc1>>NC(=O)Cc1ccccc1CCc1nc(Nc2ccc(CNCCO)cc2)ncc1C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050164402A1,BrCc1ccccc1.C=CCCCCCCCCCO>>C=CCCCCCCCCCOCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US04435406,CC(=O)Nc1cc2c(cc1[N+](=O)[O-])OC(C)(C)O2>>CC1(C)Oc2cc(N)c([N+](=O)[O-])cc2O1,,CO,,C[O-].[Na+],,test
US20070249670A1,C#CC[Sn](CCCC)(CCCC)CCCC.COC(=O)[C@@H](NC(=O)c1cc2ccccc2cc1NC(=O)Nc1c(C)cc(Br)cc1C)C1CCCCC1>>C#CCc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)N[C@H](C(=O)OC)C2CCCCC2)c(C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,,,,test
US20080167361A1,COc1cc(Br)ccc1CC(=O)N1C(=O)OC[C@@H]1C(C)C.N#CCBr>>COc1cc(Br)ccc1[C@H](CC#N)C(=O)N1C(=O)OC[C@@H]1C(C)C,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20120220577A1,CCOC(=O)CC(C(=O)OCC)=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cc(Cl)cc(Cl)c1>>CCOC(=O)C/C(=C\c1cc(Cl)cc(Cl)c1)C(=O)OCC,,c1ccccc1,,O=C([O-])O.[Na+],,test
US20110257198A1,Cc1cccn2cc(C[C@@H]3CCCCN3C(=O)OC(C)(C)C)nc12.II>>Cc1cccn2c(I)c(C[C@@H]3CCCCN3C(=O)OC(C)(C)C)nc12,,ClCCl,,O=S([O-])O.[Na+],,test
US20120142668A1,COc1ccc(NC(=O)/C=C/[C@H](CCc2ccccc2)NC(=O)[C@H](C2CCCC2)N(C(=O)[O-])C(C)(C)C)cc1.O=C(O)C(F)(F)F>>COc1ccc(NC(=O)/C=C/[C@H](CCc2ccccc2)NC(=O)[C@@H](N)C2CCCC2)cc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20130115194A1,CO.COC(=O)[C@@H]1CC(=O)CN1C(=O)OC(C)(C)C.COP(=O)(OC)C(=[N+]=[N-])C(C)=O>>CO/C=C1\C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20150111885A1,Cc1ccc[n+](-c2ccc([N+](=O)[O-])cc2[N+](=O)[O-])c1.NC1CCC1.[Cl-]>>Cc1ccc[n+](C2CCC2)c1.[Cl-],,CCCCO,,,,test
US20070072873A1,COC(=O)c1cscc1N.O=C(Cl)C(F)Cl>>COC(=O)c1cscc1NC(=O)C(F)Cl,,ClCCl,ClCCl,CCN(CC)CC,,test
US20110281838A1,COC(=O)c1cc(-c2nc(N)nc(C)c2C#Cc2ccc(N)nc2)ccc1Cl>>Cc1nc(N)nc(-c2ccc(Cl)c(C(=O)O)c2)c1C#Cc1ccc(N)nc1,,C1CCOC1,O,[Li+].[OH-],,test
US05532258,CC(=O)NCc1ccc(C(=O)CCl)cc1C.NC(=S)N=C(N)N>>CC(=O)NCc1ccc(-c2csc(N=C(N)N)n2)cc1C,,CCO,,,,test
US05977105,O=C(CCc1ccc(-c2ccc(O)cc2)cc1)CCc1cccnc1>>Oc1ccc(-c2ccc(CCC(O)CCc3cccnc3)cc2)cc1,,CCO,,[BH4-].[Na+],,test
US20130261106A1,CC(C)Oc1cc(N2CCCN(C)CC2)ccc1[N+](=O)[O-]>>CC(C)Oc1cc(N2CCCN(C)CC2)ccc1N,[Pd],CO,,,,test
US20110311461A1,CCC(Br)(C(=O)O)c1ccccc1.COC(=O)c1sccc1N>>COC(=O)c1sccc1NC(C(=O)O)c1ccccc1,,CC#N,,,,test
US20130090352A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=C(N[C@H]1CCOC[C@@H]1O)c1cc(Br)c2c(n1)CCCC2>>CC1(C)OB(c2cc(C(=O)N[C@H]3CCOC[C@@H]3O)nc3c2CCCC3)OC1(C)C,,Cc1ccccc1,,ClCCl,CC(=O)[O-].[K+],test
US20040138277A1,CCOC(=O)C(Br)CC.Oc1ccccc1>>CCOC(=O)C(CC)Oc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060154975A1,CCOC(=O)c1csc(N)n1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>O=C(O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,c1ccncc1,,,,test
US20100075994A1,CCI.CCOC(=O)CC(=O)CC>>CCOC(=O)C(CC)C(=O)CC,,CCO,,C,C[O-].[Na+],test
US20090298893A1,Cc1ccc(C(=O)C(C)CN2CCCCC2)cc1.O=C(O)C[C@H](O)C(=O)O>>Cc1ccc(C(=O)C(C)CN2CCCCC2)cc1.O=C([O-])CC(O)C(=O)[O-],,CCOC(C)=O,,,,test
US20070179127A1,CC(C)(C)OC(=O)NC1CCNC1.O=S(=O)(Cl)c1cccc2cncc(Br)c12>>CC(C)(C)OC(=O)NC1CCN(S(=O)(=O)c2cccc3cncc(Br)c23)C1,,ClCCl,,CCN(CC)CC,,test
US20110021520A1,CC(C)(C)OC(=O)NC(CO)(c1cccc(Br)c1)C(F)F.Cl>>Cl.NC(CO)(c1cccc(Br)c1)C(F)F,,C1COCCO1,,,,test
US20150094281A1,BrCC1CC1.C=C[C@H](CCC(C)C)[C@@H](O)[C@H](C)OCc1ccc(OC)cc1>>C=C[C@H](CCC(C)C)[C@@H](OCC1CC1)[C@H](C)OCc1ccc(OC)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20070027318A1,CCCN.COc1cc2nccc(Oc3ccc(N)c([N+](=O)[O-])c3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCCNC(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1[N+](=O)[O-],,CCN(CC)CC,ClC(Cl)Cl,O=C([O-])O.[Na+],,test
US06265446B1,CC(C)C[C@@H](C(=O)NN(CC(C)C)S(=O)(=O)CCCN(C)C)[C@H](C/C=C/c1ccccc1)C(=O)NOC1CCCCO1.Cc1ccc(S(=O)(=O)O)cc1>>CC(C)C[C@@H](C(=O)NN(CC(C)C)S(=O)(=O)CCCN(C)C)[C@H](C/C=C/c1ccccc1)C(=O)NO.Cc1ccc(S(=O)(=O)O)cc1,,CO,,O,,test
US20020156081A1,Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2-c1ccc(C=O)cc1>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2-c1ccc(CO)cc1,,CO,,C1CCOC1,[BH4-].[Na+],test
US20070010670A1,O=C(Cl)c1cc(Br)c(O)c(Br)c1.c1ccc2c(c1)NCCO2>>O=C(c1cc(Br)c(O)c(Br)c1)N1CCOc2ccccc21,,CCOC(C)=O,,,,test
US20160264554A1,CC(C)(C)OC(=O)Nc1ccc(C(=O)NC2CC(Nc3ncc(Cl)c(-c4cn(S(=O)(=O)c5ccccc5)c5ccccc45)n3)CC(O[Si](C)(C)C(C)(C)C)C2)cc1>>Nc1ccc(C(=O)NC2CC(O)CC(Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)C2)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04078071,O=S(Cl)Cl.OC(CCc1ccccc1)Cn1ccnc1>>Cl.ClC(CCc1ccccc1)Cn1ccnc1,,ClCCl,,,,test
US20040058978A1,CCOC(=O)CN(C)C(=O)c1cccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)c1>>CN(CC(=O)O)C(=O)c1cccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)c1,,CCO,,[Na+].[OH-],,test
US20010038849A1,CCOP(=O)(Cl)Cl.O=C(OCCO)c1ccc(C(=O)OCCO)cc1>>CCOP(=O)(Cl)Cl.O=C(OCCO)c1ccc(C(=O)OCCO)cc1,CN(C)c1ccncc1,ClCCl,,,,test
US06353111B1,COC(=O)/C(=C/C1CCCCCC1)c1ccc(S(C)(=O)=O)c(C(F)(F)F)c1>>CS(=O)(=O)c1ccc(/C(=C\C2CCCCCC2)C(=O)O)cc1C(F)(F)F,,CCO,,[Na+].[OH-],,test
US20080255122A1,CI.O=C1NS(=O)(=O)C(c2ccccc2)=C1Cl>>CN1C(=O)C(Cl)=C(c2ccccc2)S1(=O)=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070244159A1,CCOC(=O)CC(C)(C)C#Cc1cc([N+](=O)[O-])ccc1NCCO[Si](C)(C)C(C)(C)C>>CCOC(=O)CC(C)(C)c1cc2cc([N+](=O)[O-])ccc2n1CCO,Cl[Pd]Cl,CC#N,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040259910A1,CCOC(=O)C1CN=C(Cc2cc(C)cc(OC)c2)c2cc(OC)c(OC)cc21>>CCOC(=O)c1cnc(Cc2cc(C)cc(OC)c2)c2cc(OC)c(OC)cc12,[Pd],Cc1ccccc1C,,,,test
US20060084654A1,CC(C)(C)Oc1ccc(CBr)cc1.Nc1nccn2c(C3CCC3)nc(-c3cccc(O)c3)c12>>CC(C)(C)Oc1ccc(COc2cccc(-c3nc(C4CCC4)n4ccnc(N)c34)c2)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040048853A1,CCC(c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1)N1CCN(C(=O)OC(C)(C)C)CC1c1ccc(C)cc1>>CCC(c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1)N1CCNCC1c1ccc(C)cc1,,O,O=C(O)C(F)(F)F,Cc1ccccc1,,test
US04791209,C=CCc1c(O)c(Cl)cc2c(-c3c(F)cccc3F)noc12.O=C(OO)c1cccc(Cl)c1>>OCC1Cc2c(c(Cl)cc3c(-c4c(F)cccc4F)noc23)O1,,ClCCl,,O,[Na+].[OH-],test
US20060235231A1,COC(=O)C=CC=CCSc1ccc2ccccc2c1.NO>>O=C(C=CC=CCSc1ccc2ccccc2c1)NO,,C1CCOC1,,CO,[K+].[OH-],test
US20120028959A1,C=[N+]=[N-].Nc1c(I)cccc1C(=O)O>>COC(=O)c1cccc(I)c1N,,CCOCC,CO,,,test
US06613760B1,CCOC(=O)c1cc2c(COC3CCCCO3)cccc2[nH]1.ClCc1ccc(Cl)c(Cl)c1>>CCOC(=O)c1cc2c(COC3CCCCO3)cccc2n1Cc1ccc(Cl)c(Cl)c1,,CN(C)C=O,,[H-].[Na+],,test
US20050234112A1,CC(C)(CCn1cncn1)NCC(O)c1ccc(OCc2ccccc2)c(CO)c1>>CC(C)(CCn1cncn1)NCC(O)c1ccc(O)c(CO)c1,[Pd],CO,,,,test
US04590201,Cc1cccc(C(=O)Cl)c1.Clc1ccccc1>>Cc1cccc(C(=O)c2ccc(Cl)cc2)c1,,Clc1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20040029857A1,Cc1cnc(Cl)cc1N.OB(O)c1ccccc1>>Cc1cnc(-c2ccccc2)cc1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,c1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20040038993A1,CCOC(=O)c1c[nH]nc1N.CN(C)C(=O)/C(Br)=C/C1CCCCC1>>CCOC(=O)c1cnn2c(C3CCCCC3)c(Br)cnc12,,CC(=O)O,CCO,Br,,test
US09434725B2,CC(C)(C)OC(=O)N1CCN(c2cccc(-n3ncc4cnc(Cl)cc43)n2)CC1.CCCC[Sn](CCCC)(CCCC)c1cnccn1>>CC(C)(C)OC(=O)N1CCN(c2cccc(-n3ncc4cnc(-c5cnccn5)cc43)n2)CC1,,CC(=O)N(C)C,,,,test
US20050250810A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1cnc2c(c1)CCCN2>>CC(C)(C)OC(=O)N1CCCc2cccnc21,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20050009804A1,COC(=O)c1sc(-c2ccccc2)cc1NN(C)C.O=C(Cl)c1ccc(Cl)cc1Cl>>COC(=O)c1sc(-c2ccccc2)cc1N(C(=O)c1ccc(Cl)cc1Cl)N(C)C,,ClCCCl,,N#N,,test
US04822787,C=CCOC(=O)CC(=O)[C@H](C)[C@H]1NC(=O)[C@@H]1[C@@H](C)O[Si](C)(C)C(C)(C)C.Cc1ccc(S(=O)(=O)N=[N+]=[N-])cc1>>C=CCOC(=O)C(=[N+]=[N-])C(=O)[C@H](C)[C@H]1NC(=O)[C@@H]1[C@@H](C)O[Si](C)(C)C(C)(C)C,,CC#N,,CCN(CC)CC,,test
US20120184509A1,Clc1cccnc1Cl.OC1CCCNC1>>OC1CCN(c2ncccc2Cl)CC1,,CS(C)=O,,O,,test
US20100080770A1,C=CCCCCCC(=O)N[C@H](C(=O)OC)C(C)(C)C>>C=CCCCCCC(=O)N[C@H](C(=O)O)C(C)(C)C,,C1CCOC1,CO,[Li+].[OH-],,test
US04311645,C=C[Mg]Cl.CCCCCC#CCC#C/C=C/C=O>>C=CC(O)/C=C/C#CCC#CCCCCC,,C1CCOC1,,,,test
US20110118245A1,COc1cc2ncnc(Sc3cccc(N)c3)c2cc1OC.O=C(Nc1cc(C(F)(F)F)nn1-c1ccccc1)Oc1ccccc1>>COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(C(F)(F)F)nn4-c4ccccc4)c3)c2cc1OC,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090324581A1,CC(C)(C)OC(=O)N1CCc2cc(O)ccc21.OCc1ccc(-c2ccccc2)cc1C(F)(F)F>>CC(C)(C)OC(=O)N1CCc2cc(OCc3ccc(-c4ccccc4)cc3C(F)(F)F)ccc21,,C1CCOC1,Cc1ccccc1,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070197588A1,CCOC(=O)C1Cc2ccccc2C(c2ccc(Cl)c(Cl)c2)C1>>OCC1Cc2ccccc2C(c2ccc(Cl)c(Cl)c2)C1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20030229051A1,O=[N+]([O-])c1cccc2c1sc1c(Nc3cccc(Br)c3)ncnc12>>Nc1cccc2c1sc1c(Nc3cccc(Br)c3)ncnc12,[Ni],CO,,,,test
US20120022069A1,CCOC(=O)C(O)P(=O)(OCC)OCC.CI>>CCOC(=O)C(OC)P(=O)(OCC)OCC,,ClC(Cl)Cl,,,,test
US09428503B2,CCOC(=O)C=CN(C)C.COc1ccc(CN)cc1.O=C(Cl)c1cc(Br)ccc1F>>CCOC(=O)C(=CNCc1ccc(OC)cc1)C(=O)c1cc(Br)ccc1F,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20150210652A1,C1COCCN1.Clc1nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n1>>ClC(Cl)(Cl)c1nc(N2CCOCC2)nc(C(Cl)(Cl)Cl)n1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090270350A1,CC(C)(C)c1cc(N)n(-c2ccc(O)cc2)n1.COc1ccc(Cn2c(C)cc(OCc3ccccc3CN)cc2=O)cc1.O=C(Cl)Cl>>COc1ccc(Cn2c(C)cc(OCc3ccccc3CNC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(O)cc3)cc2=O)cc1,,ClCCl,,O=C([O-])O.[Na+],,test
US20100273764A1,COc1ccc(CCl)cc1.COc1ccc(CNc2nc(C)nc(Cl)n2)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(Cl)n2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20130129753A1,CC[C@H](C)[C@@H]([C@@H](CC(=O)O)OC)N(C)C(=O)[C@@H](NC(=O)[C@@]1(C)CCCN1C)C(C)C.O=C(Oc1c(F)c(F)c(F)c(F)c1F)C(F)(F)F>>CC[C@H](C)[C@@H]([C@@H](CC(=O)Oc1c(F)c(F)c(F)c(F)c1F)OC)N(C)C(=O)[C@@H](NC(=O)[C@@]1(C)CCCN1C)C(C)C,,ClCCl,,c1ccncc1,,test
US20120094995A1,C1COCCO1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN1C2CCC1(C(NS(=O)C(C)(C)C)c1ccccc1)CC2.CO>>Cc1cccc(C)c1C(=O)NC(c1ccccc1)C12CCC(CC1)N2C,,C1COCCO1,,Cl,,test
US20120230924A1,Brc1ccc2c(c1)CCN2.COc1ccc(C=O)cc1O>>COc1ccc(CN2CCc3cc(Br)ccc32)cc1O,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US06977264B2,CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(c2ccccc2N)CC1.N#Cc1ccccc1S(=O)(=O)Cl>>CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(c2ccccc2NS(=O)(=O)c2ccccc2C#N)CC1,,ClCCCl,,c1ccncc1,,test
US20150158865A1,CC(C)(C)OC(=O)N1CCC[C@@H](n2ccc3cc(C4CC4)cc(F)c3c2=O)C1.Cl>>Cl.O=c1c2c(F)cc(C3CC3)cc2ccn1[C@@H]1CCCNC1,,C1COCCO1,,,,test
US20160221945A1,COCCOc1cc(-c2ccc(C(F)(F)F)nc2)cc(CNC(=O)c2cc(F)c[nH]2)n1.O=S(=O)(Cl)c1ccc(F)cc1>>COCCOc1cc(-c2ccc(C(F)(F)F)nc2)cc(CNC(=O)[C@@H]2C[C@@H](F)CN2S(=O)(=O)c2ccc(F)cc2)n1,,ClCCl,O,CCN(CC)CC,,test
US05319100,CC(C)(C)c1cc(C=C2CCNC2=O)cc(C(C)(C)C)c1O.CCOC(C)=O.CN(C)C=O>>CN(C)C(=O)Oc1ccccc1,,CCOC(C)=O,,[H-].[Na+],,test
US20030055093A1,CC(=O)c1ccc2c(c1)CC(NC(=O)c1ccc(F)cc1)C2>>CC(O)c1ccc2c(c1)CC(NC(=O)c1ccc(F)cc1)C2,,CO,,[BH4-].[Na+],,test
US20020115861A1,CC(C)(O)CNc1c(N)c(Cl)nc2ccccc12.COCCC(=O)Cl>>COCCC(=O)Nc1c(Cl)nc2ccccc2c1NCC(C)(C)O,,CC#N,,,,test
US20090118305A1,CC(C)(C)OC(=O)N1CCC(n2cc(-c3cnc(N)c(-c4nc5ncc(F)cc5o4)c3)cn2)CC1>>Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2ncc(F)cc2o1,,ClCCl,,Cl,N,test
US20150344468A1,C1=COCCC1.CC(C)(O)C#Cc1ccc(Br)nc1>>CC(C)(C#Cc1ccc(Br)nc1)OC1CCCCO1,Cc1ccc(S(=O)(=O)O)cc1,ClCCl,,[Cl-].[NH4+],,test
US20070010528A1,Cn1c(CN2CCN(C(=O)CCS(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC2)c(Br)s/c1=N\C(=O)OC(C)(C)C>>Cn1c(CN2CCN(C(=O)CCS(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC2)c(Br)sc1=N,,O=C(O)C(F)(F)F,,,,test
US20050153959A1,COC(=O)C(=Cc1cc(C)c2nn(COCC[Si](C)(C)C)cc2c1)C(=O)OC(C)(C)C>>COC(=O)C(Cc1cc(C)c2nn(COCC[Si](C)(C)C)cc2c1)C(=O)OC(C)(C)C,[Pd],CO,,,,test
US20030119890A1,CC(C)(C)NC(=S)Nc1ccc(C#N)cc1.CCOC(=O)C(=O)Cl>>CC(C)(C)N1C(=O)C(=O)N(c2ccc(C#N)cc2)C1=S,,ClCCl,,,,test
US20120322841A1,CN(C)/C=C1\C(=O)C(C)(C)CC1c1ccc(C#N)cc1.Cl.NN>>CC1(C)CC(c2ccc(C#N)cc2)c2cn[nH]c21.Cl,CC(=O)O,CCO,,,,test
US05747523,C1CCNCC1.Fc1ccc(C(OCCCl)c2ccc(F)cc2)cc1>>Fc1ccc(C(OCCN2CCCCC2)c2ccc(F)cc2)cc1,,CCOCC,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20040024034A1,C=CCc1cc(OCc2ccccc2)cc(CC=C)c1O.Cc1ccc(S(=O)(=O)OCCc2nc(-c3ccccc3)oc2C)cc1>>C=CCc1cc(OCc2ccccc2)cc(CC=C)c1OCCc1nc(-c2ccccc2)oc1C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130096113A1,CI.COC(=O)c1ccc2nc(S)oc2c1>>COC(=O)c1ccc2nc(SC)oc2c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130184222A1,O=C(O)CCl.c1ccc2[nH]nnc2c1>>O=C(O)Cn1nnc2ccccc21,,O,,Cl,[Na+].[OH-],test
US20090176778A1,COC(=O)c1nn2c(Cl)cc(Br)cc2c1C(=O)OC>>O=C(O)c1cc2cc(Br)cc(Cl)n2n1,,O,,O=S(=O)(O)O,[Na+].[OH-],test
US04066772,O=c1[nH]c2ccccc2n1C1=CCNCC1.O=c1[nH]c2ccccc2n1CCCCl>>O=c1[nH]c2ccccc2n1CCCN1CC=C(n2c(=O)[nH]c3ccccc32)CC1,,CC(=O)CC(C)C,O,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US06841684B2,CN(C)S(=O)(=O)n1c(C=O)cnc1[Si](C)(C)C(C)(C)C>>CN(C)S(=O)(=O)n1ccnc1[Si](C)(C)C(C)(C)C,,C1CCOC1,,,,test
US20140148433A1,COc1ccc(Cn2c(=O)[nH]c3cnc(-c4nn(Cc5ccccc5F)c5ncccc45)nc32)c(OC)c1.ICCN1CCOCC1>>COc1ccc(Cn2c(=O)n(CCN3CCOCC3)c3cnc(-c4nn(Cc5ccccc5F)c5ncccc45)nc32)c(OC)c1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20040158071A1,CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)Nc1cccc(-c2csc(SCC(=O)NC3CCN(Cc4ccc(Cl)c(Cl)c4)CC3)n2)c1>>O=C(CSc1nc(-c2cccc(NC(=O)[C@@H]3Cc4ccccc4CN3)c2)cs1)NC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20160009726A1,CCCc1cc2nc(C(=O)O)ccc2o1.C[C@@H]1C[C@H](NC(=O)OC(C)(C)C)CN(c2ccncc2N)C1>>CCCc1cc2nc(C(=O)Nc3cnccc3N3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](C)C3)ccc2o1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06326359B1,COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(COS(C)(=O)=O)nc32)[C@H](O)[C@@H]1O.CS(=O)(=O)N[C@@H]1CC[C@@H](N)CC1>>COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CN[C@@H]4CC[C@@H](NS(C)(=O)=O)CC4)nc32)[C@H](O)[C@@H]1O,,CCO,ClCCl,CCN(C(C)C)C(C)C,,test
US20070197450A1,Cc1ccc(CCl)cc1.c1ccc(COC[C@H]2O[C@@H](c3ccc4cc[nH]c4c3)[C@H](OCc3ccccc3)[C@@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)cc1>>Cc1ccc(Cn2ccc3ccc([C@@H]4O[C@H](COCc5ccccc5)[C@@H](OCc5ccccc5)[C@H](OCc5ccccc5)[C@H]4OCc4ccccc4)cc32)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US04818765,C1COCCN1.O=C(CBr)c1ccc(F)cc1>>O=C(CN1CCOCC1)c1ccc(F)cc1,,Cc1ccccc1,,,,test
US20160185786A1,BrBr.O=c1[nH]cnn2cncc12>>O=c1[nH]cnn2c(Br)ncc12,,CN(C)C=O,,,,test
US05322859,BrCCc1ccccc1.CNC>>CN(C)CCc1ccccc1,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US05232923,Br.CCNCCc1ccc(OC)c(OC)c1>>Br.CCNCCc1ccc(O)c(O)c1,,CC(=O)O,,,,test
US03983239,Cc1ccc2c(c1)C1CNCCC1N2.OCCBr>>Cc1ccc2c(c1)C1CN(CCO)CCC1N2,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04937251,c1ccc(CNCCCCCCOCCc2ccccn2)cc1>>NCCCCCCOCCc1ccccn1,[Pd],CCO,,,,test
US20100041698A1,COc1ccccc1CN1Cc2ccccc2N=C1SC.NO>>COc1ccccc1CN1Cc2ccccc2N=C1NO,,CC(C)O,,,,test
US20090298829A1,Oc1ccc(C(F)(F)F)cc1>>OC1CCC(C(F)(F)F)CC1,,CC(=O)O,,[H][H],,test
US20030078289A1,CCOC(=O)c1cc2c(Cl)c(Oc3ccc(OC)c(C(C)C)c3)c(Cl)cc2[nH]1.CI>>COC(=O)c1cc2c(Cl)c(Oc3ccc(OC)c(C(C)C)c3)c(Cl)cc2n1C,,CN(C)C=O,,[H-].[Na+],,test
US20060194836A1,BrC(Br)(Br)Br.NC(=O)c1cc(CO)ccn1>>NC(=O)c1cc(CBr)ccn1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090156642A1,CCOC(C)=O.CCOC(C)=O.CN(Cc1cc(S(=O)(=O)c2cccnc2)n(-c2cc(F)ccc2F)n1)C(=O)OC(C)(C)C>>CNCc1cc(S(=O)(=O)c2cccnc2)n(-c2cc(F)ccc2F)n1.O=C(O)/C=C/C(=O)O,,CCO,,Cl,,test
US20160229816A1,Br[Mg]C1CC1.O=Cc1cc(Cl)cc(Br)c1>>OC(c1cc(Cl)cc(Br)c1)C1CC1,,C1CCOC1,,[Cl-].[NH4+],,test
US20110118330A1,C=CCOC[C@@H](CC=C)OCOCCOC>>COCCOCO[C@@H]1CC=CCOC1,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,ClCCl,,,,test
US20130116234A1,CC(C)c1cccc(-c2c(C(=O)OC(C)(C)C)c(N3CCCC3)nc3ccc(Cl)cc23)c1>>CC(C)c1cccc(-c2c(C(=O)O)c(N3CCCC3)nc3ccc(Cl)cc23)c1,,C1COCCO1,,Cl,,test
US20090264399A1,C[C@@H]1CCCC[C@@H]1n1c(=O)n(Cc2cccc([N+](=O)[O-])c2)c2cnc3[nH]ccc3c21>>C[C@@H]1CCCC[C@@H]1n1c(=O)n(Cc2cccc(N)c2)c2cnc3[nH]ccc3c21,[Fe],O,,CCO,[Cl-].[NH4+],test
US03953415,CC(C)(C)OC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1>>NC(=O)C[C@H](NC(=O)OCc1ccccc1)C(=O)NCC(=O)O,,CCOCC,,O=C(O)C(F)(F)F,,test
US20050245551A1,Cc1ccc(N)cc1-n1cnc2ccc(N3CCN(C)CC3)cc2c1=O.O=C(Cl)c1cc(F)cc(F)c1>>Cc1ccc(NC(=O)c2cc(F)cc(F)c2)cc1-n1cnc2ccc(N3CCN(C)CC3)cc2c1=O,,ClCCl,,CCN(CC)CC,,test
US06713473B1,CC(C)n1c2c(c3cc([N+](=O)[O-])ccc31)CCCC2>>CC(C)n1c2c(c3cc(N)ccc31)CCCC2,[Fe],CC(=O)O,,,,test
US04665087,C=C(C)C(=O)OC.CN>>CNCC(C)C(=O)OC,,CO,,,,test
US20160176891A1,COc1ccc2c(c1)CCCN2.Cc1nc(Cl)c2cc(C)oc2n1>>COc1ccc2c(c1)CCCN2c1nc(C)nc2oc(C)cc12,Cl,CCCCO,,,,test
US07947676B2,COC(OC)N(C)C.N#Cc1c(OCCO)n[nH]c1N>>CN(C)C=Nc1[nH]nc(OCCO)c1C#N,,CC#N,,,,test
US20070225292A1,CC(C)(C)OC(=O)N1CCCCC1CNC(=O)c1ncccc1NC(=O)c1ccc(CBr)c2ccccc12.c1nc[nH]n1>>CC(C)(C)OC(=O)N1CCCCC1CNC(=O)c1ncccc1NC(=O)c1ccc(Cn2cncn2)c2ccccc12,,CN(C)C=O,,,,test
US05541168,CC(C)C1C(=O)N(CSc2ccccc2)S(=O)(=O)N1C.O=S(=O)(Cl)Cl>>CC(C)C1C(=O)N(CCl)S(=O)(=O)N1C,,ClCCl,,,,test
US20100016282A1,CC(C)(C)[Si](C)(C)OCCC(CO)N1CCN(C(=O)OCc2ccccc2)CCC1=O.CI>>COCC(CCO[Si](C)(C)C(C)(C)C)N1CCN(C(=O)OCc2ccccc2)CCC1=O,,CN(C)C=O,,[H-].[Na+],,test
US20040082629A1,Nc1nc(C(F)(F)F)c(Br)s1.O=C(Cl)c1ccc(Cl)c(Cl)c1>>O=C(Nc1nc(C(F)(F)F)c(Br)s1)c1ccc(Cl)c(Cl)c1,,c1ccncc1,,Cl,,test
US20130210804A1,COC(=O)[C@@H]1CC[C@H]2CCc3cc(N=[N+]=[N-])ncc3C(=O)N2C1>>COC(=O)[C@@H]1CC[C@H]2CCc3cc(N)ncc3C(=O)N2C1,[Pd],CCOC(C)=O,CO,,,test
US04897495,N#CC12CCCN1CCC2>>NCC12CCCN1CCC2,O=[Pt],CC(=O)O,,Cl,,test
US20090176786A1,CNc1cc(Cl)c(SC(F)(F)C(F)F)c(Cl)c1.O=C=NC(=O)c1c(F)cccc1F>>CN(C(=O)NC(=O)c1c(F)cccc1F)c1cc(Cl)c(SC(F)(F)C(F)F)c(Cl)c1,,CCOCC,,CCCCCC,,test
US05200415,CCOC(=O)c1cnn2c(CC)cccc12.OC1CN2CCC1CC2>>CCc1cccc2c(C(=O)OC3CN4CCC3CC4)cnn12,,c1ccccc1,,[Na],,test
US05506228,CC(=O)C(Cl)=NNc1ccccc1Cl.Sc1ccc(Cl)cc1>>CC(=O)C(=NNc1ccccc1Cl)Sc1ccc(Cl)cc1,,CC(C)=O,,,,test
US03963706,O=C1CN(C2CCCCC2)CN1c1ccc([N+](=O)[O-])cc1>>Nc1ccc(N2CN(C3CCCCC3)CC2=O)cc1,[Ni],CCO,,,,test
US20060194801A1,O=[N+]([O-])c1cnc2c(c1)OCC(CO)N2>>Nc1cnc2c(c1)OCC(CO)N2,[Pd],CO,,,,test
US05686458,COc1cccc2c(N3Cc4ccccc4CC3C)nc(Cl)nc12.Nc1ccc(F)cc1>>COc1cccc2c(N3Cc4ccccc4CC3C)nc(Nc3ccc(F)cc3)nc12.Cl,,CN(C)C=O,,,,test
US20140235629A1,CC(C)(C)[Si](C)(C)Cl.C[C@@](N)(c1ccc(Cl)cc1)C(O)c1cccc(Cl)c1>>CC(C)(C)[Si](C)(C)OC(c1cccc(Cl)c1)[C@](C)(N)c1ccc(Cl)cc1,,CN(C)C=O,O,c1c[nH]cn1,,test
US20150336986A1,Cn1c(=O)c2c(-c3cccc(F)c3)n3c(c2n(C)c1=O)C(c1nc(Cl)cs1)CC3CO[Si](C)(C)C(C)(C)C>>Cn1c(=O)c2c(-c3cccc(F)c3)n3c(c2n(C)c1=O)C(c1nc(Cl)cs1)CC3CO,,CO,O,O=C(O)C(F)(F)F,,test
US20100234340A1,COC(=O)c1[nH]cnc1CN(CCCl)Cc1ccccc1>>COC(=O)c1ncn2c1CN(Cc1ccccc1)CC2,,CC#N,,,,test
US20130261106A1,CC(C)Oc1cc(N2CCC[C@@H](N(C)C3COC3)C2)ccc1[N+](=O)[O-]>>CC(C)Oc1cc(N2CCC[C@@H](N(C)C3COC3)C2)ccc1N,[Pd],CCO,,NN,O,test
US06150373,CCOC(=O)Cc1ccc(Nc2ncc3c(n2)N(C)C(=O)N(c2c(Cl)cccc2Cl)C3)cc1>>CN1C(=O)N(c2c(Cl)cccc2Cl)Cc2cnc(Nc3ccc(CCO)cc3)nc21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130344030A1,C1COCCO1.C=O.CC(=O)CC(=O)OC(C)(C)C>>CC(=O)C(CO)(CO)C(=O)OC(C)(C)C,,C1CCOC1,,CCN(CC)CC,,test
US20150266890A1,Cc1cc(N)ccc1F.Cc1ccc(S(=O)(=O)Cl)cc1C(=O)Cl>>Cc1cc(NC(=O)c2cc(S(=O)(=O)Cl)ccc2C)ccc1F,,Cc1ccccc1,,,,test
US04977272,C1CCOC1.CCOC(=O)CN.COC(OC)OC.NO.[N-]=C=O.c1ccncc1>>CCOC(=O)CNC(=O)Nc1ccc(C=NO)cc1,,CO,,Cl,,test
US20110046127A1,C1COCCN1.O=S(=O)(O)c1cnc2ccc(Cl)nn12>>O=S(=O)(c1cnc2ccc(Cl)nn12)N1CCOCC1,,O=P(Cl)(Cl)Cl,,CCN(CC)CC,,test
US03950336,CC(C)OC(=O)CC(=N)N.CCOC(=O)C(C#N)=Cc1ccccc1>>CCOC(=O)C1=C(N)NC(N)=C(C(=O)OC(C)C)C1c1ccccc1,,CCO,,C,C[O-].[Na+],test
US20080300232A1,CN(C(=O)COc1cccc(Cl)c1)C1CCNCC1.O=Cc1ccn(-c2ccc(C(F)(F)F)cc2)c1>>CN(C(=O)COc1cccc(Cl)c1)C1CCN(Cc2ccn(-c3ccc(C(F)(F)F)cc3)c2)CC1,,CC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20040049072A1,CC(=CCO)c1cc2c(cc1O)C(C)(C)CCC2(C)C.CCCI>>CCCOc1cc2c(cc1/C(C)=C\CO)C(C)(C)CCC2(C)C,,CCOC(C)=O,CN(C)C=O,[Cs+].[F-],,test
US20110301155A1,BrCc1ccccc1.CC(C)Cc1cc(O)c(N)c(C#N)c1>>CC(C)Cc1cc(C#N)c(N)c(OCc2ccccc2)c1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04242121,O=C(O)c1cc(Cl)ccc1Cl.Oc1cccc(Cl)c1>>O=C(O)c1cc(Cl)ccc1Oc1cccc(Cl)c1,,Cc1ccccc1,,[H-].[Na+],,test
US20120149676A1,FC1CCNCC1.Nc1cc(F)c(C(=O)O)cc1[N+](=O)[O-]>>Nc1cc(N2CCC(F)CC2)c(C(=O)O)cc1[N+](=O)[O-],,CN(C)C=O,,Cl,,test
US05556864,CN1CCCCC1CCOc1ccccc1CCc1ccccc1.Cl>>CN1CCCCC1CCOc1ccccc1CCc1ccccc1.Cl,,C1COCCO1,,CCOC(C)=O,,test
US20100305084A1,C1CN(C2CNC2)CCO1.O=Cc1nc2c(N3CCOCC3)nc(Cl)nc2s1>>Clc1nc(N2CCOCC2)c2nc(CN3CC(N4CCOCC4)C3)sc2n1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150080364A1,CC(C)(C)OC(=O)N1CCNCC1.OC(c1ccc2c(c1)OC(F)(F)O2)c1ccc2c(c1)OC(F)(F)O2>>CC(C)(C)OC(=O)N1CCN(C(c2ccc3c(c2)OC(F)(F)O3)c2ccc3c(c2)OC(F)(F)O3)CC1,,ClCCl,,O=S(Cl)Cl,,test
US20120189713A1,O=C(Cl)OCc1ccccc1.O=C(O)CNc1ccc(O)cc1>>O=C(O)CN(C(=O)OCc1ccccc1)c1ccc(O)cc1,,CN1CCCC1=O,,O,,test
US20070287724A1,CCCc1nc2c(N)nc3cccnc3c2n1CC1(O)CCCC1>>CCCc1nc2c(N)nc3c(c2n1CC1(O)CCCC1)NCCC3,O=[Pt],,,O=C(O)C(F)(F)F,,test
US06200999B1,CCOC(=O)c1onc(OC)c1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1onc(OC)c1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20050054645A1,CN(CC(O)CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)C(=O)OCc1ccccc1>>CN(CC(=O)CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)C(=O)OCc1ccccc1,,ClC(Cl)Cl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20090018103A1,CN(C[C@H](C=O)NC(=O)OC(C)(C)C)C(=O)OCC[Si](C)(C)C.Cl[Mg]C1CCCCC1>>CN(C[C@@H](NC(=O)OC(C)(C)C)[C@H](O)C1CCCCC1)C(=O)OCC[Si](C)(C)C,,Cc1ccccc1,,,,test
US20030144285A1,Cc1ccccc1I.N#CCCCN1CCCCC1.O=C(O)C(F)(F)F>>Cc1ccccc1C(=O)CCCN1CCCCC1,,CCOCC,ClCCl,CC#N,,test
US20120178926A1,CC[C@@H](N)c1nnco1.O=C1CCCC1>>CC[C@@H](NC1CCCC1)c1nnco1,,C1CCOC1,,CC(=O)O,O=C([O-])O.[Na+],test
US20130053370A1,CCOC(=O)c1ccc(C)c(NC(=O)c2csc3c(SC)ncnc23)c1.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)c1ccc(C)c(NC(=O)c2csc3c(S(C)=O)ncnc23)c1,,ClCCl,,,,test
US20040186132A1,CCc1cc(Br)ccc1N.O=[N+]([O-])c1ccccc1B(O)O>>CCc1cc(-c2cccc([N+](=O)[O-])c2)ccc1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20050277674A1,CN(C)C1(c2ccccc2)CCC(CC(=O)N2CCCC(c3c[nH]c4ccccc34)C2)CC1.C[Si](C)(C)Cl>>CN(C)C1(c2ccccc2)CCC(CC(=O)N2CCCC(c3c[nH]c4ccccc34)C2)CC1.Cl,,CCC(C)=O,,,,test
US06204221B1,C=C[Sn](CCCC)(CCCC)CCCC.Cn1nc(-c2nc(Cl)c(Cl)cc2F)c(Cl)c1OC(F)F>>C=Cc1nc(-c2nn(C)c(OC(F)F)c2Cl)c(F)cc1Cl,,CN(C)C=O,,,,test
US20090239859A1,COC(=O)c1cccc(-c2cnccc2C(=O)N(C(C)C)C(C)C)c1N>>COC(=O)c1cccc2c1[nH]c(=O)c1ccncc12,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20160102059A1,CCOc1cc([N+](=O)[O-])ccc1P(C)(=O)OCC>>CCOc1cc(N)ccc1P(C)(=O)OCC,[Pd],,,CCO,,test
US20040142921A1,COC(=O)[C@@H](N)Cc1ccc(O)cc1.Cc1ccccc1C(=O)C1CCCCC1=O>>COC(=O)C(Cc1ccc(O)cc1)Nc1ccccc1C(=O)c1ccccc1C,[Pd],COc1ccccc1,,CO,O,test
US20050026964A1,Cn1c(-c2c(F)c(F)c(F)c(F)c2F)c(C(=O)[O-])c(Nc2ccc(I)cc2F)cc1=O.NCCO>>Cn1cc(C(=O)NCCO)c(Nc2ccc(I)cc2F)cc1=O,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20130331397A1,CC(C)(C)OC(=O)N1C[C@@H](F)C[C@@H]1c1cc(F)cc(C#N)c1>>N#Cc1cc(F)cc([C@H]2C[C@H](F)CN2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100113465A1,CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)C2.Cc1cc(F)cc([Mg]Br)c1.ClCCl>>Cc1cc(F)cc(C2CC3(CCNCC3)C2)c1.Cl,,C1CCOC1,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20120302540A1,CN1C[C@@H](c2ccccc2)[C@@]2(CCCN(C(=O)[C@@H](CCOc3ccccc3)NC(=O)OC(C)(C)C)C2)C1=O>>CN1C[C@@H](c2ccccc2)[C@@]2(CCCN(C(=O)[C@H](N)CCOc3ccccc3)C2)C1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130079328A1,CC(C)(C)OC(=O)NCc1ccc(Cl)c(F)c1.Cn1cc(B2OC(C)(C)C(C)(C)O2)ccc1=O>>Cn1cc(-c2ccc(CNC(=O)OC(C)(C)C)cc2F)ccc1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20110124634A1,CCOC(=O)CBr.CCOC(=O)CC(=O)OCC>>CCOC(=O)CC(C(=O)OCC)C(=O)OCC,,C1CCOC1,,[H-].[Na+],,test
US20060223826A1,CCOC(=O)C(F)(F)F.CN(C)C=O.O=C(O)C=Cc1cccc([N+](=O)[O-])c1>>Nc1cccc(CCCNC(=O)C(F)(F)F)c1,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US04643761,CC(C)(C)NS(=O)(=O)c1c(Cl)cccc1-c1ccccc1>>NS(=O)(=O)c1c(Cl)cccc1-c1ccccc1,,O=C(O)C(F)(F)F,,O,,test
US20080306064A1,CCOC(=O)c1c(SC)ccc(N)c1N.S=C=Nc1cccc(Cl)c1Cl>>CSc1ccc2nc(Nc3cccc(Cl)c3Cl)[nH]c2c1C(=O)O,,CC#N,,CCN=C=NCCCN(C)C,Cl,test
US05364875,CCOC(=O)c1cccc(CSc2nc(-c3ccc(OC)cc3)c(-c3ccc(OC)cc3)[nH]2)c1>>COc1ccc(-c2nc(SCc3cccc(CO)c3)[nH]c2-c2ccc(OC)cc2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04172130,CCCCOC(=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12>>CC(C)C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O,,C1COCCO1,CCOCC,Cl,,test
US06350749B1,Cc1ccc(C)c(C2CC(=O)c3c(C)coc3C2)c1.Cl.N=C(N)NN>>Cc1ccc(C)c(C2C/C(=N\NC(=N)N)c3c(C)coc3C2)c1.Cl,,CCO,,Cl,,test
US20110218192A1,C[Si](C)(C)N=C=N[Si](C)(C)C.N#Cc1cccc(-c2ccc3c(c2)C(=O)CC(c2cccnc2)O3)c1>>N#C/N=C1\CC(c2cccnc2)Oc2ccc(-c3cccc(C#N)c3)cc21,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US05670503,Fc1ccc(-c2nn3c(c2-c2ccncc2)NNCC3)cc1.O=C(O)Cc1c[nH]c2ccccc12>>O=C(Cc1c[nH]c2ccccc12)N1CCn2nc(-c3ccc(F)cc3)c(-c3ccncc3)c2N1,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20120022030A1,CN(C)CCCl.Oc1cc(Br)ccc1F>>CN(C)CCOc1cc(Br)ccc1F,,CC(C)=O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20090149651A1,Nc1c(-c2ncccn2)cc(-c2cncc(F)c2)cc1[N+](=O)[O-]>>Nc1cc(-c2cncc(F)c2)cc(-c2ncccn2)c1N,[Pd],CC(=O)N(C)C,,N#N,,test
US07799894B2,COc1ccc(-c2nc3cccc(N)c3nc2-c2ccc(OC)cc2)cc1.O=[N+]([O-])c1ccc(F)cc1>>COc1ccc(-c2nc3cccc(Nc4ccc(N)cc4)c3nc2-c2ccc(OC)cc2)cc1,,CS(C)=O,,CC(C)(C)O[K],,test
US20120203002A1,Nc1ncc(-c2cnn(CCO)c2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12.O=C1O[C@H]([C@@H](O)CO)C([O-])=C1O>>Nc1ncc(-c2cnn(CCO)c2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12.O=C1O[C@H]([C@@H](O)CO)C(O)=C1O,,O,,C1CCOC1,,test
US05371099,C1CCNC1.CC(=O)CC(=O)Nc1ccc([N+](=O)[O-])cc1>>CC(=CC(=O)Nc1ccc([N+](=O)[O-])cc1)N1CCCC1,,c1ccccc1,,,,test
US20100130506A1,CC(C)(C)OC(=O)N1CCC(C(=O)N2CCC3(CC2)CN/C(=N\C(=O)c2nc(Cl)c(N)nc2N)N3)CC1.Cl>>Cl.Nc1nc(N)c(C(=O)/N=C2\NCC3(CCN(C(=O)C4CCNCC4)CC3)N2)nc1Cl,,C1COCCO1,,,,test
US20150094306A1,Cc1cc(C(C)N2Cc3c(ccnc3N)C2=O)cnc1OCC(F)(F)F.O=C(Cl)CCl>>Cc1cc(C(C)N2Cc3c(ccnc3NC(=O)CCl)C2=O)cnc1OCC(F)(F)F,,ClCCl,O,c1ccncc1,,test
US04124704,BrCc1cc(Br)c2oc(Br)c(-c3ccccc3)c2c1.[C-]#N>>N#CCc1cc(Br)c2oc(Br)c(-c3ccccc3)c2c1,,O,,CN(C)C=O,,test
US20110288076A1,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)O.Nc1ccc(Oc2ccc(F)cc2)cc1>>CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)Nc1ccc(Oc2ccc(F)cc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04226775,O=C(O)/C=C/CC(=O)c1ccccc1.O=C(O)[C@@H]1CCCN1>>O=C(C/C=C/C(=O)N1CCC[C@H]1C(=O)O)c1ccccc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20040063691A1,Brc1cccs1.CCc1c(C(=O)N2CCC(=O)CC2)nc(-c2ccccc2Cl)n1-c1ccc(Cl)cc1>>CCc1c(C(=O)c2cccs2)nc(-c2ccccc2Cl)n1-c1ccc(Cl)cc1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US04057647,COC(=O)C=C(C)c1ccc(-c2ccc(F)cc2F)cc1>>COC(=O)CC(C)c1ccc(-c2ccc(F)cc2F)cc1,[Pd],CCO,,,,test
US20090291988A1,Brc1ccc(Br)nc1.O=C(OCC(F)(F)F)C(F)(F)F>>O=C(c1ccc(Br)cn1)C(F)(F)F,,Cc1ccccc1,,[Li]CCCC,,test
US20130190307A1,O=P(Cl)(Cl)Cl.Oc1cnc2ccc(Br)cc2n1>>Clc1cnc2ccc(Br)cc2n1,CN(C)C=O,,,,,test
US20140018533A1,CC(=O)N(C)C.CCOC(=O)C1=C(Nc2ccc(OCCN(C)C)cc2C)OC(=Cc2c[nH]c3ncccc23)C1=O.OCC1CC1>>Cc1cc(OCCN(C)C)ccc1NC1=C(C(=O)OCC2CC2)C(=O)C(=Cc2c[nH]c3ncccc23)O1.O=CO,[Zn],CC(=O)N(C)C,,,,test
US04814349,CC(C)=NNC(C)(C)C.O=C(Cl)c1ccccc1>>CC(C)=NN(C(=O)c1ccccc1)C(C)(C)C,,CCOCC,,[Na+].[OH-],,test
US20010051726A1,CI.COc1ccc2[nH]c(S)nc2c1>>COc1ccc2[nH]c(SC)nc2c1,,CCO,O,Cl,[K+].[OH-],test
US04837333,CCOC(=O)c1ccc(C)cc1Cl.O=C1CCC(=O)N1Br>>CCOC(=O)c1ccc(CBr)cc1Cl,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20080090813A1,CNS(=O)(=O)c1cc(Br)cc(C(F)(F)F)c1.C[Sn](C)(C)c1cc(CCCOCc2ccccc2)nc(C#N)n1>>CNS(=O)(=O)c1cc(-c2cc(CCCOCc3ccccc3)nc(C#N)n2)cc(C(F)(F)F)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,CN(C)C=O,,,test
US06204293B1,COC(=O)c1ccc(Oc2ccccn2)cc1-c1ccccc1>>O=C(O)c1ccc(Oc2ccccn2)cc1-c1ccccc1,,CO,O,[Na+].[OH-],,test
US20160221945A1,FC(F)(F)c1cnc(Cl)cn1.N#Cc1ccc(F)c(B(O)O)c1>>N#Cc1ccc(F)c(-c2cnc(C(F)(F)F)cn2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US04757081,CC(C(=O)CC(=O)c1ccccc1Cl)C(=O)c1ccccc1.Nc1c(F)cccc1F>>Cc1c(-c2ccccc2)n(-c2c(F)cccc2F)c(-c2ccccc2Cl)cc1=O,,Cc1ccccc1C,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120046467A1,CC(=O)O.Nc1ccccc1-c1ccccc1>>CC(=O)Nc1ccccc1-c1ccccc1,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20020019388A1,O=C(OCc1ccccc1)N1C[C@@H]2CN(c3cccnc3)[C@@H]2C1>>c1cncc(N2C[C@H]3CNC[C@H]32)c1,[Pd],CO,,,,test
US20100009977A1,COCCCBr.O=S1(=O)NC[C@H](O)c2ccsc21>>COCCCN1C[C@@H](O)c2ccsc2S1(=O)=O,,CC(C)=O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20100197693A1,C1C[C@@H]2CNCCN2C1.Nc1ccc(C(F)(F)F)cc1.O=C(Cl)c1cc(S(=O)(=O)Cl)ccc1Cl>>O=C(c1cc(S(=O)(=O)Nc2ccc(C(F)(F)F)cc2)ccc1Cl)N1CCN2CCC[C@@H]2C1,,CO,ClCCl,O=C([O-])[O-].[Na+].[Na+],,test
US20150045393A1,CCOC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)Nc1c(C)cc(C)cc1C>>Cc1cc(C)c(NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H]2O[C@@H]2C(=O)O)c(C)c1,,CO,O,[Li+].[OH-],,test
US20090156598A1,Clc1cccc(Cl)c1Nc1nc2c(Cl)ncnc2[nH]1.Nc1ccc(C(F)(F)F)cc1>>FC(F)(F)c1ccc(Nc2ncnc3[nH]c(Nc4c(Cl)cccc4Cl)nc23)cc1,,CC(C)O,,Cl,,test
US04971982,CC1(C)CC(c2cccnc2)c2cc(C#N)ccc2O1.O=C(OO)c1cccc(Cl)c1>>CC1(C)CC(c2ccc[n+]([O-])c2)c2cc(C#N)ccc2O1,,ClCCl,,,,test
US20130059834A1,NC1CCCC(N)C1.O=C(O)c1c[nH]c2ncc(Br)nc12>>NC1CCCC(NC(=O)c2c[nH]c3ncc(Br)nc23)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04690925,NCC(=O)NC1CCCCC1.O=Cc1cc(OCCCC(=O)Cl)ccc1[N+](=O)[O-]>>NC(=O)CN(C(=O)CCCOc1ccc([N+](=O)[O-])c(C=O)c1)C1CCCCC1,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20130045965A1,CN1CCn2nc(Nc3cc(-c4ccnc(-n5ncc6cc(C(C)(C)C)cc(F)c6c5=O)c4CO)nn(C)c3=O)cc2C1.O=C(OO)c1cccc(Cl)c1>>Cn1nc(-c2ccnc(-n3ncc4cc(C(C)(C)C)cc(F)c4c3=O)c2CO)cc(Nc2cc3n(n2)CC[N+](C)([O-])C3)c1=O,,CO,ClCCl,,,test
US04188395,CCOC(=O)/C=C(/C)N.CCOC(=O)CC(=O)COC(C)=O.COc1cccc(C=O)c1>>CCOC(=O)C1=C(C)NC(COC(C)=O)=C(C(=O)OCC)C1c1cccc(OC)c1,,CCO,,,,test
US07592360B2,Cc1ccc(COC(=O)N2CC[C@H](CC(=O)O)[C@H](F)C2)cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cc1ccc(COC(=O)N2CC[C@H](CN)[C@H](F)C2)cc1,,C1COCCO1,Cc1ccccc1,CCN(CC)CC,[Na+].[OH-],test
US06545009B1,COC(=O)c1ccc(C(N)=O)cc1.O=C(CBr)c1ccc(Cl)cc1>>COC(=O)c1ccc(-c2nc(-c3ccc(Cl)cc3)co2)cc1,,CCO,,CN(C)C=O,,test
US05780465,ClCCl.O=C(Cl)C(=O)Cl.O=Cc1ccc(F)cc1>>O=C(O)CCc1ccc(F)cc1,,ClCCl,,O,,test
US07501425B1,CCNc1nc(SC)ncc1C=Nc1cc(OC)cc(OC)c1Cl>>CCNc1nc(SC)ncc1CNc1cc(OC)cc(OC)c1Cl,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20020193405A1,CC1CCCN(Cc2cccc(NC(=O)Nc3csc(-c4ccncc4)n3)n2)C1>>C[C@@H]1CCCN(Cc2cccc(NC(=O)Nc3csc(-c4ccncc4)n3)n2)C1,,CCCCCC,CCO,,,test
US20140011800A1,CO[C@@H]1CN(C(=O)OCc2ccccc2)C[C@H]1O.Cc1ccc(S(=O)(=O)Cl)cc1>>CO[C@@H]1CN(C(=O)OCc2ccccc2)C[C@H]1OS(=O)(=O)c1ccc(C)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20090170907A1,O=CO.[C-]#[N+]CC(=O)OCC>>CCOC(=O)c1cocn1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20060004084A1,O=C1Cc2ccccc2N1.O=C1OCc2cc(C3OCCO3)ccc21>>O=Cc1ccc2c(c1)COC2=C1C(=O)Nc2ccccc21,,C1CCOC1,O,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20130281657A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCCCNc1ncc(C=O)s1>>C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCCCNc1ncc(CO)s1,,CCO,O,[BH4-].[Na+],,test
US20090181950A1,CC(C)(C)OC(=O)N1CCNCC1.CC(C)(C)[Si](C)(C)Oc1ccc(CCCS(=O)(=O)[O-])cc1>>CC(C)(C)OC(=O)N1CCN(CCc2ccc(O[Si](C)(C)C(C)(C)C)cc2)CC1,,CC#N,,O=C([O-])O.[Na+],,test
US20110021498A1,CC(C)(C)OC(=O)n1ccc2cc(O[Si](C)(C)C(C)(C)C)ccc21.C[Si](C)(C)CCOCn1cc([N+](=O)[O-])cc(I)c1=O>>CC(C)(C)OC(=O)n1c(-c2cc([N+](=O)[O-])cn(COCC[Si](C)(C)C)c2=O)cc2cc(O[Si](C)(C)C(C)(C)C)ccc21,,CCCCCC,,,,test
US20150175562A1,CC(C)(C)c1cc(-c2cc(C(=O)O)ccc2C=C2CCCCC2)cc(C(C)(C)C)c1>>CC(C)(C)c1cc(-c2cc(C(=O)O)ccc2CC2CCCCC2)cc(C(C)(C)C)c1,[Pd],CO,,[H][H],,test
US20150175604A1,CS(=O)(=O)Cl.Cc1nnc2ccc3c(cc(-c4ccn(C5(CC#N)CNC5)n4)n3Cc3cccc(Cl)c3)n12>>Cc1nnc2ccc3c(cc(-c4ccn(C5(CC#N)CN(S(C)(=O)=O)C5)n4)n3Cc3cccc(Cl)c3)n12,,ClCCl,,CCN(CC)CC,,test
US05684022,O=C1c2ccccc2C(=O)N1CCOc1ccc(Cn2cccn2)cc1>>NCCOc1ccc(Cn2cccn2)cc1,,CO,,NN,O,test
US20020006946A1,Cc1cc([N+](=O)[O-])cc(C)c1Oc1ccc(O)c(S(=O)(=O)CC2CC2)c1>>Cc1cc(N)cc(C)c1Oc1ccc(O)c(S(=O)(=O)CC2CC2)c1,,CO,,,,test
US20100152168A1,COc1ccc(S(=O)(=O)n2c(=O)n(C(C(=O)N3CCC(NC(=O)OC(C)(C)C)CC3)c3ccccc3)c3cc(C#N)ccc32)cc1>>COc1ccc(S(=O)(=O)n2c(=O)n(C(C(=O)N3CCC(N)CC3)c3ccccc3)c3cc(C#N)ccc32)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060079478A1,CC(O)[Si](C)(C)C.COC(=O)CCC(C)=CCc1c(O)c2c(c(C)c1OC)COC2=O>>COC(=O)CCC(C)=CCc1c(OC)c(C)c2c(c1OCC[Si](C)(C)C)C(=O)OC2,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060004017A1,COCCOCCOc1cc2nc[nH]c(=O)c2cc1OC.O=S(Cl)Cl>>COCCOCCOc1cc2ncnc(Cl)c2cc1OC,,CN(C)C=O,,,,test
US20030187264A1,O=P(Cl)(Cl)Cl.O=c1cc(C(F)(F)F)[nH]c(=O)n1-c1cc(Oc2ccccc2[N+](=O)[O-])c(Cl)cc1F>>O=c1cc(C(F)(F)F)nc(Cl)n1-c1cc(Oc2ccccc2[N+](=O)[O-])c(Cl)cc1F,,O,,CCN(CC)CC,Cc1ccccc1,test
US20010014691A1,CN.O=[N+]([O-])c1cccc(OCCCCl)c1>>CNCCCOc1cccc([N+](=O)[O-])c1,,CO,,,,test
US20030114469A1,C=C(C)Cn1c(N)cc(=O)[nH]c1=O.COS(=O)(=O)OC>>C=C(C)Cn1c(N)cc(=O)n(C)c1=O,,O,,[Na+].[OH-],,test
US20060229325A1,Clc1ncc(Br)c(Cl)n1.NC1(CO)CCCC1>>OCC1(Nc2nc(Cl)ncc2Br)CCCC1,,CC#N,,CCN(CC)CC,,test
US20100004312A1,Cc1c(C)c(-c2cccc(CO)c2)c(C)c(C)c1O.Cc1ccc(S(=O)(=O)OCCCS(C)(=O)=O)cc1>>Cc1c(C)c(-c2cccc(CO)c2)c(C)c(C)c1OCCCS(C)(=O)=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100087427A1,BrCc1cccc(OCc2ccccc2)c1.COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2O)C(C)C)ccc1OC>>COCCCOc1cc(C(=O)N(C[C@@H]2CNC[C@H]2OCc2cccc(OCc3ccccc3)c2)C(C)C)ccc1OC,,O,,CC#N,CC#N,test
US20150291552A1,COc1ccc(Oc2sc3cc(OC)ccc3c2-c2ccc(F)cc2)cc1>>Oc1ccc(Oc2sc3cc(O)ccc3c2-c2ccc(F)cc2)cc1,,ClCCl,,BrB(Br)Br,,test
US20070060607A1,CCOC(=O)c1cnc(Cl)c2c(COc3ccc(C(=O)OC(C)(C)C)cc3)csc12.N>>CCOC(=O)c1cnc(N)c2c(COc3ccc(C(=O)OC(C)(C)C)cc3)csc12,,C1COCCO1,,,,test
US20160185769A1,CCS(=O)(=O)c1ccc(Oc2c(C)cccc2CBr)c(Br)c1.O=C1CCCN1>>CCS(=O)(=O)c1ccc(Oc2c(C)cccc2CN2CCCC2=O)c(Br)c1,,C1CCOC1,,[H-].[Na+],,test
US20100324040A1,CC(C)Oc1cc(Nc2nc(Cl)ccc2[N+](=O)[O-])n[nH]1.N[C@@H](CO)c1ccc(F)cn1>>CC(C)Oc1cc(Nc2nc(N[C@@H](CO)c3ccc(F)cn3)ccc2[N+](=O)[O-])n[nH]1,,CCCCO,CCOC(C)=O,CCN(C(C)C)C(C)C,Cl,test
US20150209445A1,CC(C)(C)OC(=O)N1C[C@@H](CCl)c2c1cc(OCc1ccccc1)c1ccccc21>>CC(C)(C)OC(=O)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21,[Pd],C1CCOC1,,O=C[O-].[NH4+],,test
US06150407,COC(=O)c1cc([N+](=O)[O-])c(Oc2ccc(OC)cc2)c([N+](=O)[O-])c1>>COC(=O)c1cc(N)c(Oc2ccc(OC)cc2)c(N)c1,[Pd],CC(=O)O,,[H][H],,test
US20100305131A1,CCOC(=O)C(=N)NO.O=C(n1ccnc1)n1ccnc1>>CCOC(=O)c1noc(=O)[nH]1,,C1COCCO1,,C1CCC2=NCCCN2CC1,,test
US20070191395A1,CC(C)C(=O)CBr.O=C(O)COCc1ccccc1>>CC(C)C(=O)COC(=O)COCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020099212A1,COC(=O)c1ccc2c(C)nn(Cc3ccc(Cl)cc3Cl)c2c1>>Cc1nn(Cc2ccc(Cl)cc2Cl)c2cc(C(=O)O)ccc12,,CCO,,[Na+].[OH-],,test
US06500853B1,COC(=O)c1ccc(S(=O)(=O)CCc2c(CO)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1>>O=C(O)c1ccc(S(=O)(=O)CCc2c(CO)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1,,C1CCOC1,,CO,[Na+].[OH-],test
US20020107422A1,CC(=CCBr)CBr.CCCC(=O)[O-]>>CCCC(=O)OCC=C(C)CBr,,CN(C)C=O,,O,,test
US20160222014A1,C[C@H]1CN(c2ccc(Nc3ncc4ccn(Cc5cccnc5N(C)S(C)(=O)=O)c4n3)nc2)CCN1C(=O)OC(C)(C)C>>C[C@H]1CN(c2ccc(Nc3ncc4ccn(Cc5cccnc5N(C)S(C)(=O)=O)c4n3)nc2)CCN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140296136A1,CN(C)CCCO.COC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C1Cc3ccccc3C1)NC(=O)O[C@@H]1C[C@H]1CCCCCc1c(nc3ccccc3c1O)O2>>COC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C1Cc3ccccc3C1)NC(=O)O[C@@H]1C[C@H]1CCCCCc1c(nc3ccccc3c1OCCCN(C)C)O2,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110060054A1,C=[N+](C)C.COc1ccc(C=C2CCCC2=O)c(OC)c1.[Cl-]>>COc1ccc(C=C2CCC(CN(C)C)C2=O)c(OC)c1.Cl,,CC#N,,,,test
US20110301178A1,CC(C)=C1C=CC=C1.Nc1cccc([N+](=O)[O-])c1C(=O)O>>CC(C)=C1C2C=CC1c1c2cccc1[N+](=O)[O-],,COCCOC,,CC(C)(C)ON=O,,test
US20100137302A1,CC(=O)Cl.Cc1ccc(Nc2ccc3c(c2)N(c2nc4c(s2)C(=O)NC(C)(C)C4)CCO3)cn1>>CC(=O)N(c1ccc(C)nc1)c1ccc2c(c1)N(c1nc3c(s1)C(=O)NC(C)(C)C3)CCO2,,C1CCOC1,,c1ccncc1,,test
US20050267105A1,CCOC(=O)c1nc2n(c(=O)c1OCc1ccccc1)CCOC2(C)C>>CC1(C)OCCn2c1nc(C(=O)O)c(OCc1ccccc1)c2=O,,C1CCOC1,CCO,O,[Li]O,test
US04442109,C=O.COc1ccc2c(O)ccnc2c1>>COc1ccc2c(O)c(CO)cnc2c1,,[Na+],[OH-],,,test
US06051599,CCCCc1cscc1Br.CN(C)C=O>>CCCCc1csc(C=O)c1Br,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20020042409A1,CS(=O)(=O)OC1CN(C(c2ccccc2)c2ccccc2)C1.N>>NC1CN(C(c2ccccc2)c2ccccc2)C1,,CO,,,,test
US20130102776A1,CC(C)(C)OC(=O)N1CCC(CCCO)CC1>>CC(C)(C)OC(=O)N1CCC(CCC=O)CC1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20140213586A1,Nc1cccc(-c2cnco2)c1.O=C(c1c[nH]c2ccccc12)C(Cl)c1ccccc1>>O=C(c1c[nH]c2ccccc12)C(Nc1cccc(-c2cnco2)c1)c1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US05637569,CC(=O)OC[C@H]1O[C@@H](OC(C)=O)[C@H](N2C(=O)c3ccccc3C2=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O.CS[Si](C)(C)C>>CS[C@@H]1O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1N1C(=O)c2ccccc2C1=O,,ClCCl,,CC(C)NC(C)C,,test
US04820834,CC(C)C(=O)Cl.CN1C(=O)[C@@H](N)N=C(c2ccccc2)c2ccccc21>>CC(C)C(=O)N[C@H]1N=C(c2ccccc2)c2ccccc2N(C)C1=O,,ClCCl,,CCN(CC)CC,,test
US20120004240A1,CC(C)(C)c1cc(N)[nH]n1.CCOC=C(C#N)C(=O)OCC>>CCOC(=O)c1cnc2cc(C(C)(C)C)nn2c1N,,CC(=O)O,,,,test
US20090326074A1,CC(C)(C)OC(=O)NCCC(O)c1cccc(OCC2CCCCCC2)c1>>CC(C)(C)OC(=O)NCCC(=O)c1cccc(OCC2CCCCCC2)c1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US05100460,C=C(CSc1ccccc1Cl)c1ccccc1.O=C(OO)c1cccc(Cl)c1>>C=C(CS(=O)c1ccccc1Cl)c1ccccc1,,ClCCl,,,,test
US20130005728A1,COc1nc(N2C[C@@H](c3ccccc3OC)[C@H](C(=O)O)C2)cc(N(CCc2ccc(OC(F)(F)F)cc2)C(=O)OC(C)(C)C)n1>>COc1nc(NCCc2ccc(OC(F)(F)F)cc2)cc(N2C[C@@H](c3ccccc3OC)[C@H](C(=O)O)C2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120028959A1,COC(=O)c1c(F)c(F)c(-c2ccc(C=O)cc2)c(F)c1F>>COC(=O)c1c(F)c(F)c(-c2ccc(CO)cc2)c(F)c1F,,CO,,[BH4-].[Na+],,test
US04590193,O=[N+]([O-])c1ccccc1CCN1CCN(c2ccccc2)CC1>>Nc1ccccc1CCN1CCN(c2ccccc2)CC1,,CCOCC,,,,test
US20110071126A1,Fc1ccc(CBr)c(CCBr)c1F.O=C1CCc2ccc(Br)cc21>>O=C1c2cc(Br)ccc2CC12CCc1c(ccc(F)c1F)C2,,C1CCOC1,,[H-].[Na+],,test
US20040192686A1,NCCCO.[O-][n+]1nc(Cl)nc2ccccc21>>[O-][n+]1nc(NCCCO)nc2ccccc21,,COCCOC,,,,test
US20100292210A1,OC(CNCc1ccc(Cl)nc1Cl)c1ccccc1>>Clc1ccc2c(n1)OC(c1ccccc1)CNC2,,C1CCOC1,ClCCl,CO,[H-].[Na+],test
US05461026,CC(=O)OC(C)=O.OC(CF)c1cccnc1SCc1ccccc1>>CC(=O)OC(CF)c1cccnc1SCc1ccccc1,,C1CCOC1,,O,O=S(=O)(O)O,test
US20110257189A1,NCc1ccc(I)cc1.O=C(Cl)OCc1ccccc1>>O=C(NCc1ccc(I)cc1)OCc1ccccc1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20090029958A1,COC(=O)C1(CN=[N+]=[N-])CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)C1(CN=[N+]=[N-])CCNCC1,,C1COCCO1,,Cl,,test
US20110015175A1,CCN(CC)S(F)(F)F.COc1cc(Nc2nc3n(n2)CCC(=O)CC3c2ccc(F)cc2)ccc1-n1cnc(Cl)c1.O=C(O)C(F)(F)F>>COc1cc(Nc2nc3n(n2)CCC(F)(F)CC3c2ccc(F)cc2)ccc1-n1cnc(Cl)c1.O=C(O)C(F)(F)F,,O=C([O-])O,[Na+],O=C(O)C(F)(F)F,,test
US20030166639A1,CC(C)(C)OC(=O)Nc1ccc(OC(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-c2ccc(C3CC3)nc2)c1>>O=C1CC(c2cccc(-c3ccc(C4CC4)nc3)c2)=Nc2ccc(OC(F)(F)F)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090280416A1,CCOC(=O)c1ccc(O)cc1.OCCCCCCBr>>O=C(O)c1ccc(OCCCCCCO)cc1,,O,,CC(=O)N(C)C,O=C([O-])[O-].[K+].[K+],test
US20050245563A1,CC(=O)c1c(O)c2cc(F)ccc2[nH]c1=O.NN>>Cc1[nH]nc2c1c(=O)[nH]c1ccc(F)cc12,,CN(C)C=O,,O,,test
US20090281068A1,CC(Br)C(=O)Br.CC(C)C(O)C(=O)O>>CC1OC(=O)C(C(C)C)OC1=O,,CC(C)=O,,CCN(CC)CC,,test
US20130172292A1,CCn1ncc2ncnc(Cl)c21>>CCn1ncc2ncncc21,[Pd],CCOC(C)=O,,,,test
US20090143352A1,CN(C)C(=O)CC1CCNC1.COc1ccccc1-c1cn(COCC[Si](C)(C)C)c2ncc(Br)cc12>>COc1ccccc1-c1cn(COCC[Si](C)(C)C)c2ncc(N3CCC(CC(=O)N(C)C)C3)cc12,[Cu]I,,,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US20110003787A1,COC[C@H](C)Oc1cc(Oc2cnc(S(C)(=O)=O)cn2)cc(-c2ccc(C3=NC(O)[C@H](C)O3)[nH]2)c1>>C[C@@H](CO)Oc1cc(Oc2cnc(S(C)(=O)=O)cn2)cc(-c2ccc(C3=NC(O)[C@H](C)O3)[nH]2)c1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20150051171A1,Cc1ccc(F)c(NC(=O)C=NO)c1.O>>Cc1ccc(F)c2c1C(=O)C(=O)N2,,O,,O=S(=O)(O)O,,test
US05574030,ClC(CCN1CCOCC1)c1ccccc1.O=C1COCC(Cc2ccccc2)N1>>O=C1COCC(Cc2ccccc2)N1C(CCN1CCOCC1)c1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20160083391A1,O=c1[nH]c(CNCCCl)nc2nn(Cc3ccccc3)c(Nc3ccccc3)c12>>O=c1c2c(Nc3ccccc3)n(Cc3ccccc3)nc2nc2n1CCNC2,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050137395A1,CC(Br)Br.COC(=O)c1c(C)oc2cc(Oc3ccnc4cc(O)ccc34)ccc12>>COC(=O)c1c(C)oc2cc(Oc3ccnc4cc(OCCBr)ccc34)ccc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110224429A1,CC[N+](=O)[O-].COC(CCCC=O)OC>>C/C(=C\CCCC=O)[N+](=O)[O-],,CCCCCC,CCOC(C)=O,,,test
US20060122263A1,[N-]=[N+]=N[C@H]1CCO[C@@H](C(c2ccccc2)c2ccccc2)C1>>N[C@H]1CCO[C@@H](C(c2ccccc2)c2ccccc2)C1,[Pd],,,,,test
US20020156081A1,Cc1ccc(S(=O)(=O)OC2CCOCC2)cc1.Nc1ncnc2[nH]nc(-c3ccc(Oc4ccccc4)cc3)c12>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CCOCC1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20020032184A1,CCOC(=O)C(=O)C(Cl)C(=O)CC.Sc1cc(Cl)cc(Cl)c1>>CCOC(=O)C(=O)C(Sc1cc(Cl)cc(Cl)c1)C(=O)CC,,CC(C)=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20070010511A1,C[Si](C)(C)CCOCCl.Cc1cccc2c1NC(=O)C2(C)C>>Cc1cccc2c1N(COCC[Si](C)(C)C)C(=O)C2(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20060069128A1,COC(=O)c1cc(C(=O)[O-])cc([N+](=O)[O-])c1.O=C(Cl)C(=O)Cl>>COC(=O)c1cc(C(=O)Cl)cc([N+](=O)[O-])c1,CN(C)C=O,ClCCl,,,,test
US20100029484A1,O=C1OC(=O)C2C3CCC(O3)C12.OCc1ccccc1>>O=C(O)C1C2CCC(O2)C1C(=O)OCc1ccccc1,,C1COCCO1,,,,test
US20110136764A1,CCOP(=O)(OCC)C(O)c1ccc(N)cc1.CNC(=O)c1ccccc1Nc1nc(Cl)ncc1C(F)(F)F.CO>>CCOP(=O)(OCC)C(OC)c1ccc(Nc2ncc(C(F)(F)F)c(Nc3ccccc3C(=O)NC)n2)cc1,,CO,,O=C(O)C(F)(F)F,,test
US20100190747A1,O=[N+]([O-])c1ccc(F)cc1.OCCCC(F)(F)F>>O=[N+]([O-])c1ccc(OCCCC(F)(F)F)cc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US05047411,C=O.CCN(C=O)c1nc2ccc(CCc3ccco3)cc2o1.CNC>>CCNc1nc2ccc(CCc3ccc(CN(C)C)o3)cc2o1,,CC(=O)O,,Cl,,test
US05538940,COC(=O)/C=C(/OC)c1ccccc1CP(=O)(OC)OC.O=Cc1ccc(OCc2ccccc2)cc1>>COC(=O)/C=C(/OC)c1ccccc1C=Cc1ccc(OCc2ccccc2)cc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20130116234A1,CCOC(=O)CC(=O)Nc1c(C#Cc2ccccc2Cl)cc(Cl)cc1C(F)(F)F>>CCOC(=O)c1c(Cc2ccccc2Cl)c2cc(Cl)cc(C(F)(F)F)c2[nH]c1=O,,CS(C)=O,,[H-].[Na+],,test
US20130303551A1,CCOC(=O)c1cnn(C)c1N.O=C(Cl)c1ccc(Br)cc1>>CCOC(=O)c1cnn(C)c1NC(=O)c1ccc(Br)cc1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20160009718A1,CC1(C)CO1.CCOC(=O)c1c(C)c(C(C)C2CCNCC2)n2nc(C)ccc12>>CCOC(=O)c1c(C)c(C(C)C2CCN(CC(C)(C)O)CC2)n2nc(C)ccc12,,CO,,CCN(C(C)C)C(C)C,,test
US20060205715A1,Cc1c(O)ccc2c1CCC2=O.N#Cc1ccc(Cl)nc1>>Cc1c(Oc2ccc(C#N)cn2)ccc2c1CCC2=O,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110105566A1,BrCc1csc(Br)n1.CSc1cccc(C(=NO)c2nnnn2C)c1>>CSc1cccc(C(=NOCc2csc(Br)n2)c2nnnn2C)c1,,CC#N,,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US20050124685A1,C=C(C=O)C[C@@H]1C[C@H](O)[C@]2(C)O[C@@H]3C[C@@H]4O[C@@H]5C[C@]6(C)O[C@]7(C)CC[C@@H]8O[C@@H]9C[C@]%10(C)O[C@@H]%11C(C)=CC(=O)O[C@H]%11C[C@H]%10O[C@H]9C[C@@H](C)[C@H]8O[C@H]7C[C@H]6O[C@@]5(C)CC=C[C@H]4O[C@H]3C[C@H]2O1.CC1(C)OO1>>C=C(C=O)CC1CC(O)[C@]2(C)OC3CC4OC5C[C@]6(C)O[C@]7(C)CCC8OC9C[C@]%10(C)OC%11C(C)=CC(=O)OC%11CC%10OC9C[C@@H](C)C8OC7CC6O[C@]5(C)CC5OC5C4OC3CC2O1,,CC(C)=O,,,,test
US20090143352A1,CC(C)NC(=O)CBr.COc1ccccc1-c1cn(S(=O)(=O)c2ccc(C)cc2)c2ncc(-c3cc(F)c(NC(=O)C(F)(F)F)c(C(=O)N(C)C)c3)cc12>>COc1ccccc1-c1c[nH]c2ncc(-c3cc(F)c(NCC(=O)NC(C)C)c(C(=O)N(C)C)c3)cc12,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20050148627A1,CCOC(=O)C1=Cc2cc(Cl)c(O)cc2OC1C(F)(F)F.CCc1cnc(Cl)nc1>>CCOC(=O)C1=Cc2cc(Cl)c(Oc3ncc(CC)cn3)cc2OC1C(F)(F)F,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090118282A1,CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O.FC(F)(F)c1ccc2c(SCCCCCBr)ccnc2c1>>CCOC(=O)[C@H](Cc1ccc(OCCCCCSc2ccnc3cc(C(F)(F)F)ccc23)cc1)NC(C)=O,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050171180A1,CCC(C=O)CC.COc1ccc(Cn2cccn2)cc1>>CCC(CC)C(O)c1ccnn1Cc1ccc(OC)cc1,,C1CCOC1,,[Li]CCCC,,test
US20110046162A1,COC(=O)c1ccc(-c2nc(CSc3nc4c(c(-c5ccccc5)c3C#N)CCC4)cs2)cc1>>N#Cc1c(SCc2csc(-c3ccc(C(=O)O)cc3)n2)nc2c(c1-c1ccccc1)CCC2,,C1COCCO1,,Cl,[Na+].[OH-],test
US20100016373A1,CC(C)CC(=O)c1ccc(OCc2ccc(CNC(=O)OC(C)(C)C)cc2)c(C(F)(F)F)c1O.Cl>>CC(C)CC(=O)c1ccc(OCc2ccc(CN)cc2)c(C(F)(F)F)c1O.Cl,,C1COCCO1,CCOC(C)=O,,,test
US20140249104A1,C[Si](C)(C)C#Cc1ccc(-c2ccc(F)c([C@]3(CF)C[C@@H](C(F)(F)F)OC(N)=N3)c2)cn1>>C#Cc1ccc(-c2ccc(F)c([C@]3(CF)C[C@@H](C(F)(F)F)OC(N)=N3)c2)cn1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20150274704A1,CC(C)(C)OC(=O)N1CC2CCC(=O)CC2C1.N>>CC(C)(C)OC(=O)N1CC2CCC(N)CC2C1,CC(C)O[Ti](OC(C)C)(OC(C)C)OC(C)C,CCO,,CO,[BH4-].[Na+],test
US05739079,CCOC(=O)C(Cl)C(=O)OCC.Oc1ccccc1>>CCOC(=O)C(Oc1ccccc1)C(=O)OCC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120065214A1,CCN.Cc1cc(F)c(C(=O)NC2CC2)cc1-n1ccnc(NC2(c3ccccc3OCCCl)CC2)c1=O>>CCNCCOc1ccccc1C1(Nc2nccn(-c3cc(C(=O)NC4CC4)c(F)cc3C)c2=O)CC1,,C1CCOC1,C1COCCO1,,,test
US20090105253A1,BrC(Br)(Br)Br.CCNC(=O)c1ccc(-n2nnc(C(=O)NC3CC3)c2CO)cc1>>CCNC(=O)c1ccc(-n2nnc(C(=O)NC3CC3)c2CBr)cc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100331293A1,COC(=O)c1cc(Nc2c(C)c(-c3ccccn3)nc3cc(F)ccc23)cc(N2CCOCC2)c1>>Cc1c(-c2ccccn2)nc2cc(F)ccc2c1Nc1cc(C(=O)O)cc(N2CCOCC2)c1,,C1CCOC1,,CO,[Li+].[OH-],test
US20160083376A1,CCOC(=O)CC(=O)Cl.CCOC(=O)c1c(NC)c(-c2cccc([N+](=O)[O-])c2)nn(C)c1=O>>CCOC(=O)CC(=O)N(C)c1c(-c2cccc([N+](=O)[O-])c2)nn(C)c(=O)c1C(=O)OCC,,CC#N,,,,test
US20150065481A1,NO.O=Cc1csc(Br)n1>>ON=Cc1csc(Br)n1,,CCO,,,,test
US20150011546A1,CC(C)(C)OC(=O)N1CCN(c2cccc(N)n2)CC1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N1CCN(c2ccc(Br)c(N)n2)CC1,,CN(C)C=O,,,,test
US20040053908A1,COC(=O)c1cc2c(Oc3ccc(NC(=O)Oc4ccccc4)c(F)c3)ccnc2cc1OC.NC1CC1>>COC(=O)c1cc2c(Oc3ccc(NC(=O)NC4CC4)c(F)c3)ccnc2cc1OC,,CS(C)=O,,,,test
US05849732,CC(=O)OC(C)=O.COc1cc(NC(=O)N(Cc2ccccc2)C2CCCCC2)c(O)c(C(C)(C)C)c1>>COc1cc(NC(=O)N(Cc2ccccc2)C2CCCCC2)c(OC(C)=O)c(C(C)(C)C)c1,,ClCCl,,CCN(CC)CC,,test
US20150252038A1,CC(C)(C)[Si](C)(C)Cl.COc1ccc(CN2C(=O)CC[C@@H](O)C2=O)cc1>>COc1ccc(CN2C(=O)CC[C@@H](O[Si](C)(C)C(C)(C)C)C2=O)cc1,,ClCCl,,c1c[nH]cn1,,test
US20060173050A1,CCOc1nc(N)cc(N)c1C#N.O=C(Cl)Cc1cccs1>>CCOc1nc(NC(=O)Cc2cccs2)cc(N)c1C#N,,c1ccncc1,,O,,test
US20070112034A1,C=CC#N.NNc1cccc(C(F)(F)F)c1>>NC1=NN(c2cccc(C(F)(F)F)c2)CC1,,CCO,,C,C[O-].[Na+],test
US20130195768A1,C=CCOCCO.O=C(O)CBr>>C=CCOCCOCC(=O)O,,C1CCOC1,CCO,[H-].[Na+],,test
US20120289500A1,CCOC(=O)C(C)c1nn(NC(=O)Cc2ccc(Cl)cc2)c(=O)c2ccccc12>>CC(C(=O)O)c1nn(NC(=O)Cc2ccc(Cl)cc2)c(=O)c2ccccc12,,C1CCOC1,O,CO,[Na+].[OH-],test
US20120035168A1,Cc1cc(NC(=O)OC(C)(C)C)nc(C)c1CNC(=O)c1cnn(Cc2ccc(CN3C(=O)CCC3=O)cc2)c1>>Cc1cc(N)nc(C)c1CNC(=O)c1cnn(Cc2ccc(CN3C(=O)CCC3=O)cc2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120196845A1,CCOC(=O)c1cn(Cc2ccc(Br)cn2)c2ccccc2/c1=N/NC(=O)OC(C)(C)C>>O=c1[nH]nc2c3ccccc3n(Cc3ccc(Br)cn3)cc1-2,,Cc1ccccc1,,Cl,,test
US20040087577A1,CC(C)CCBr.O=c1[nH]c2ncccc2c(=O)o1>>CC(C)CCn1c(=O)oc(=O)c2cccnc21,,CC(=O)N(C)C,,[H-].[Na+],,test
US20130289033A1,COc1ccccc1B(O)O.O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccccc1I>>COc1ccccc1-c1ccccc1C(=O)NCCc1c[nH]c2ccc(Cl)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20120015943A1,COC(=O)c1ccc2c(c1)CC(Nc1ccnc(Cl)c1)CC2>>COC(=O)c1ccc2c(c1)CC(Nc1ccncc1)CC2,[Pd],CCO,CCOC(C)=O,,,test
US20160039838A1,C1CO[C@H]2CNC[C@H]2O1.COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1NC(=O)/C=C/CBr>>COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1NC(=O)/C=C/CN1C[C@H]2OCCO[C@H]2C1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,Cl,test
US20020037885A1,CCCCCC.O=Cc1ccccc1F>>OCc1ccccc1-c1ccccc1F,,CCCCCC,,C1CCOC1,[Li]CCCC,test
US20060183739A1,O=C(Nc1ccc(N2CCOCC2=O)cc1)[C@H]1C[C@@H](O)CN1C(=O)Nc1ccc(Cl)cc1>>O=C1C[C@H](C(=O)Nc2ccc(N3CCOCC3=O)cc2)N(C(=O)Nc2ccc(Cl)cc2)C1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20080125590A1,CN(C)S(=O)(=O)c1ccc2c(c1)CC(=O)N2.O=Cc1ccc2cccccc1-2>>CN(C)S(=O)(=O)c1ccc2c(c1)C(=Cc1ccc3cccccc1-3)C(=O)N2,,CCO,,C1CCNC1,,test
US20070254874A1,CC(C)Br.O=C(NC1CCN(Cc2ccccc2)CC1)c1n[nH]c2ccccc12>>CC(C)n1nc(C(=O)NC2CCN(Cc3ccccc3)CC2)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20110152299A1,CCO.CN(c1cncnc1)c1cccc(C#N)c1.[OH-]>>CN(c1cncnc1)c1cccc(C(=O)O)c1,,CO,ClCCl,Cl,,test
US05821366,COC(=O)c1cccc(NC(=O)N(Cc2ccccc2)C(=O)CC#N)c1>>COC(=O)c1cccc(-n2c(N)cc(=O)n(Cc3ccccc3)c2=O)c1,,ClCCl,,CCN(CC)CC,,test
US20060094767A1,BrCCOC1CCCCO1.Oc1ccc(C(F)(F)F)cc1>>FC(F)(F)c1ccc(OCCOC2CCCCO2)cc1,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US04978679,CCCC1=CC(=O)C=CC1=O.COC1=CC=CCC1>>CCCc1cc2c(cc1O)[C@@H]1CCC(=O)C[C@@H]1O2,,CO,c1ccccc1,Cl,,test
US20100004312A1,COC(Cl)Cl.Cc1cc(C)c(C)c(O)c1>>Cc1cc(C)c(C=O)c(O)c1C,Cl[Ti](Cl)(Cl)Cl,ClCCl,,[Cl-].[NH4+],,test
US20080039444A1,CCOC(=O)CCc1ccc(OCCCN2CCCCCC2)cc1>>OCCCc1ccc(OCCCN2CCCCCC2)cc1,,C1CCOC1,CCOCC,[H-].[Na+],,test
US20140023611A1,CCN(CC)c1ccc(NC(=O)c2cccc(C(=O)N(C)CCN3CCCN(C(=O)OC(C)(C)C)CC3)c2)c(-c2cc(C(=O)N[C@H]3CCCc4ccccc43)ccn2)c1>>CCN(CC)c1ccc(NC(=O)c2cccc(C(=O)N(C)CCN3CCCNCC3)c2)c(-c2cc(C(=O)N[C@H]3CCCc4ccccc43)ccn2)c1,,C1COCCO1,,Cl,,test
US20060128712A1,O=C(O)c1cc([N+](=O)[O-])ccc1N1CCOCC1.c1ccc2c(N3CCNCC3)nsc2c1>>O=C(c1cc([N+](=O)[O-])ccc1N1CCOCC1)N1CCN(c2nsc3ccccc23)CC1,,CC#N,,CCOC(C)=O,Cl,test
US04189171,Clc1ccccc1.Cn1cccc1.O=C1OC(=O)c2ccccc21>>O=C(O)c1ccccc1C(=O)c1cccn1-c1ccccc1,,Clc1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120149691A1,CN1CCN(C(CNc2c(C#N)cnn3cccc23)c2ccccc2Cl)CC1.OO>>C[N+]1([O-])CCN(C(CNc2c(C(N)=O)cnn3cccc23)c2ccccc2Cl)CC1,,CCO,,[NH4+].[OH-],,test
US20060264460A1,N#Cc1cnc2c(Cl)cc(N)cc2c1Nc1ccc(F)c(Cl)c1.O=Cc1ccnc2ccccc12>>N#Cc1cnc2c(Cl)cc(NCc3ccnc4ccccc34)cc2c1Nc1ccc(F)c(Cl)c1,,CCO,,[BH3-]C#N.[Na+],,test
US20120237875A1,CCOC(=O)C(F)(F)Br.OCc1ccccc1>>O=C(OCc1ccccc1)C(F)(F)Br,,CCCCCC,,CC(C)(C)O[K],,test
US20060229337A1,CCOC(=O)c1ccc(Nc2cc(Br)cn(C)c2=O)cc1.Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1B1OC(C)(C)C(C)(C)O1>>CCOC(=O)c1ccc(Nc2cc(-c3cccc(NC(=O)c4ccc(C(C)(C)C)cc4)c3C)cn(C)c2=O)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20050054683A1,CC(=O)NC[C@H]1CN(c2ccc(C3=CCOCC3)c(F)c2)C(=O)O1>>CC(=O)NC[C@H]1CN(c2ccc(C3CCOCC3)c(F)c2)C(=O)O1,[Pd],CO,,,,test
US20030065185A1,COC(=O)[C@@H](N)CC1CCCCC1.Cc1ccc(S(=O)(=O)N2CCC[C@H]2C(=O)O)cc1>>Cc1ccc(S(=O)(=O)N2CCC[C@H]2C(=O)N[C@@H](CC2CCCCC2)C(=O)O)cc1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20090012055A1,CC(=O)Cl.COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2OCC(=O)NCc2ccccc2CCN)cc1>>COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2OCC(=O)NCc2ccccc2CCNC(C)=O)cc1,,CCN(CC)CC,ClCCl,,,test
US20120214735A1,O=Cc1ccc(Oc2cnc(NC(=O)C(OC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)s2)cc1>>O=C(Nc1ncc(Oc2ccc(CO)cc2)s1)C(OC1CCOCC1)c1ccc(S(=O)(=O)C2CC2)cc1,,CCOC(C)=O,CO,[BH4-].[Na+],,test
US20060270673A1,N#Cc1cc(-c2ccccc2)c(-c2ccc(CBr)cc2)nc1Cl.NCc1ccc(-c2csnn2)cc1>>N#Cc1cc(-c2ccccc2)c(-c2ccc(CNCc3ccc(-c4csnn4)cc3)cc2)nc1Cl,,C1CCOC1,,CCN(C(C)C)C(C)C,CO,test
US20100239576A1,COc1cc2nccc(Oc3ccc(N)cc3F)c2cc1OC.Cc1c(C(=O)O)c(=O)n(-c2ccccc2)n1C[C@@H](C)O>>COc1cc2nccc(Oc3ccc(NC(=O)c4c(C)n(C[C@@H](C)O)n(-c5ccccc5)c4=O)cc3F)c2cc1OC,,ClCCl,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20160038504A1,Cc1ccc(N)cc1B1OC(C)(C)C(C)(C)O1.Fc1c(Br)cc(N2CCOCC2)nc1Cl>>Cc1ccc(N)cc1-c1cc(N2CCOCC2)nc(Cl)c1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20160221972A1,COC(=O)c1ccc2c(c1)OCCNC2.O=C(Cl)N1CCCCC1>>COC(=O)c1ccc2c(c1)OCCN(C(=O)N1CCCCC1)C2,,ClCCl,,CCN(CC)CC,,test
US20120295884A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@H](CO)c1cccc(Cl)c1F>>CC(C)(C)OC(=O)N[C@H](CO)c1cccc(Cl)c1F,,CO,,O=C([O-])[O-].[Na+].[Na+],,test
US20150336935A1,COc1cc(OC)cc(C(=O)[C@H]2[C@H](C)[C@H](N)C[C@H]3C(C)(C)CCC[C@]23C)c1>>C[C@@H]1[C@H](N)C[C@H]2C(C)(C)CCC[C@]2(C)[C@H]1C(=O)c1cc(O)cc(O)c1,,ClCCl,,BrB(Br)Br,CO,test
US20100137250A1,O=Cc1ccccc1S(=O)(=O)c1ccccc1>>O=S(=O)(c1ccccc1)c1ccccc1CO,,CO,,[BH4-].[Na+],,test
US20140011961A1,OCCCOc1ccc2ccccc2c1.[N-]=[N+]=NCCCS(=O)(=O)Cl>>[N-]=[N+]=NCCCS(=O)(=O)OCCCOc1ccc2ccccc2c1,,ClCCl,,CCN(CC)CC,,test
US20110312936A1,CI.O=C1CCC(NC(=O)OCc2ccccc2)CC1>>CN(C(=O)OCc1ccccc1)C1CCC(=O)CC1,,CN(C)C=O,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04539208,CC1(C)CC1C(=O)Cl.CCCCC(N)C(=O)OC(C)(C)C>>CCCCC(NC(=O)C1CC1(C)C)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US06380358B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N=C(N)NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NC(=N)NC(=O)OCc1ccccc1,,CC(C)=O,,CCN(CC)CC,,test
US20020045615A1,COc1ccc(N2CCOCC2)c2sc(N)nc12.Cc1cc(C(=O)Cl)cc(Cl)n1>>COc1ccc(N2CCOCC2)c2sc(NC(=O)c3cc(C)nc(Cl)c3)nc12,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,CO,test
US20150111885A1,CI.O=c1[nH]cc(Br)c2ccoc12>>Cn1cc(Br)c2ccoc2c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20160081334A1,C=C[N+](=O)[O-].CCc1cc(Br)cc(C)c1C1=C(OC)CCC1=O>>CCc1cc(Br)cc(C)c1C1=C(OC)CC(CC[N+](=O)[O-])C1=O,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20030199440A1,NC1CCCC1.O=S(=O)(Cl)c1ccc2c(Cl)cnc(Cl)c2c1>>O=S(=O)(NC1CCCC1)c1ccc2c(Cl)cnc(Cl)c2c1,,ClCCl,,CCN(CC)CC,,test
US20090239854A1,C=Cc1ccc(C)nc1.Cc1ccc2[nH]c3c(c2c1)CN(c1ccc(I)cc1)CC3>>Cc1ccc2c(c1)c1c(n2CCc2ccc(C)nc2)CCN(c2ccc(I)cc2)C1,,CN1CCCC1=O,,[K+].[OH-],,test
US20150065550A1,CC[C@@H]1CO1.FC(F)(F)c1ccccc1I>>CC[C@@H](O)Cc1ccccc1C(F)(F)F,,C1CCOC1,,[Li]CCCC,,test
US20110124626A1,COC(=O)c1ccc2c(c1)CCNCC2.O=C1CCC1>>COC(=O)c1ccc2c(c1)CCN(C1CCC1)CC2,,CC(=O)O,ClCCl,CCN(CC)CC,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130109682A1,C=C[C@H]1OC(c2ccncc2[N+](=O)[O-])=C[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]1O[Si](C(C)C)(C(C)C)C(C)C>>C=C[C@H]1OC(c2ccncc2[N+](=O)[O-])=C[C@@H](O)[C@@H]1O,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20030186985A1,COc1cc(CO)cc(OC)c1OCc1nc(-c2ccccc2)oc1C.O=S(Cl)Cl>>COc1cc(CCl)cc(OC)c1OCc1nc(-c2ccccc2)oc1C,,C1CCOC1,,Cc1ccccc1,,test
US20120202777A1,C1COCCO1.CC1(C)OB(c2ccc(CCC(C)(C(=O)NOC3CCCCO3)S(C)(=O)=O)cc2)OC1(C)C.O=S(=O)(OC1=CCCCCC1)C(F)(F)F>>CCCCC(OC)ONC(=O)C(C)(CCc1ccc(C2=CCCCCC2)cc1)S(C)(=O)=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,O,O=C([O-])[O-].[Na+].[Na+],test
US05605901,CC(C)COC(=O)Cl.CCCNC1Cc2ccc(C3=NNC(=O)CC3)cc2C1>>CCCN(C(=O)OCC(C)C)C1Cc2ccc(C3=NNC(=O)CC3)cc2C1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20140349990A1,Cc1cc(NC(c2ccc(Cl)cc2)c2cn(C(C)C)nc2C(=O)O)cn(C)c1=O>>Cc1cc(N2C(=O)c3nn(C(C)C)cc3C2c2ccc(Cl)cc2)cn(C)c1=O,,CO,ClCCl,,,test
US20140094462A1,C=CCC(F)(F)C(=O)N[C@@H](CO)c1ccccc1.C=CC[C@@H](C)C(=O)O>>C=CC[C@@H](C)C(=O)OC[C@H](NC(=O)C(F)(F)CC=C)c1ccccc1,,ClCCl,,,,test
US20090264416A1,Nc1ccc(C(=O)O)cc1F.O=C(NC1CC(F)(F)C1)c1cccc(CN2CCNCC2)c1>>Nc1ccc(C(=O)N2CCN(Cc3cccc(C(=O)NC4CC(F)(F)C4)c3)CC2)cc1F,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US04685960,CC(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)C(=O)Cl.CCCCCCCCCCCCO>>CCCCCCCCCCCCOC(=O)C(C)Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20100311761A1,COC(=O)Cl.O=C(Cc1ccc(Cl)c(Cl)c1)N1CCNC2CCCC(N3CCCC3)C21>>COC(=O)N1CCN(C(=O)Cc2ccc(Cl)c(Cl)c2)C2C(N3CCCC3)CCCC21,,ClCCl,,,,test
US20150274673A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cc1c(Br)cc(Cl)c2c1CCCO2>>Cc1c(B2OC(C)(C)C(C)(C)O2)cc(Cl)c2c1CCCO2,,CN(C)C=O,,O,CC(=O)[O-].[K+],test
US06306870B1,CCOC(=O)COCc1ccc(C=CC(=O)N2CCc3c([nH]c4ccccc34)C2c2ccc3c(c2)OCO3)cc1>>O=C(O)COCc1ccc(/C=C/C(=O)N2CCc3c([nH]c4ccccc34)C2c2ccc3c(c2)OCO3)cc1,,CCO,,,,test
US20110039829A1,CCOC(=O)N1CCN(C(=O)[C@@H](N)CCCC(=O)OC(C)(C)C)CC1.O=C(O)c1cc(O)n(-c2ccccc2)n1>>CCOC(=O)N1CCN(C(=O)[C@H](CCCC(=O)OC(C)(C)C)NC(=O)c2cc(O)n(-c3ccccc3)n2)CC1,,CN(C)C=O,O,ClCCCl,On1nnc2ccccc21,test
US20150133451A1,CC1CCN(c2ccn(C)n2)C1=O.O=[N+]([O-])O>>CC1CCN(c2nn(C)cc2[N+](=O)[O-])C1=O,,CC(=O)OC(C)=O,,O=C([O-])O.[Na+],,test
US04456471,CC=C(C)c1cccc(C)c1N.O=C(Cl)CCl>>CC=C(C)c1cccc(C)c1NC(=O)CCl,,ClCCl,,CCN(CC)CC,,test
US20140080808A1,Brc1cncnc1.CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(C3(c4ccc(B5OC(C)(C)C(C)(C)O5)cc4)CC3)n2CCS1>>CC1(CO)Cc2nnc(C3(c4ccc(-c5cncnc5)cc4)CC3)n2CCS1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20050131015A1,CSCCN1C(=O)C(NC(=O)c2cc3cc(Cl)sc3[nH]2)Cc2ccccc21.O=S([O-])OO>>CS(=O)(=O)CCN1C(=O)C(NC(=O)c2cc3cc(Cl)sc3[nH]2)Cc2ccccc21,,CCOC(C)=O,O,CO,,test
US04877881,ClC(Cl)(Cl)Cl.OCc1cc(C(F)(F)F)no1>>FC(F)(F)c1cc(CCl)on1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04190431,CCOC(=O)Cl.CNC(=O)N(O)c1cc(Cl)c(Cl)cc1Cl>>Cn1c(=O)on(-c2cc(Cl)c(Cl)cc2Cl)c1=O,,C1COCCO1,,[Na+].[OH-],,test
US20140294805A1,CC(=O)NCc1ccc(S(=O)(=O)C2CCCCC2)cc1>>NCc1ccc(S(=O)(=O)C2CCCCC2)cc1,,CC(C)O,,Cl,,test
US20130315841A1,C=CCCCCCCCCC(=O)O.CN(C)c1ccc2cc3c(c(-c4ccc(CO)cc4)c2c1)C(=O)CC3>>C=CCCCCCCCCC(=O)OCc1ccc(-c2c3c(cc4ccc(N(C)C)cc24)CCC3=O)cc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20110301167A1,BrCc1ccc(I)cc1.NN=C1C(=O)N(c2ccccc2F)N=C1c1ccccc1F>>O=C1C(=NNCc2ccc(I)cc2)C(c2ccccc2F)=NN1c1ccccc1F,,CN(C)C=O,O,[H-].[Na+],[Cl-].[NH4+],test
US20060025414A1,CN=C(SC)N1CCCCC1c1nnn(-c2cccc(Cl)c2)n1.COc1ccc(C(=O)NN)cc1>>COc1ccc(-c2nnc(N3CCCCC3c3nnn(-c4cccc(Cl)c4)n3)n2C)cc1,,CCO,O,,,test
US20080312235A1,CC(=O)OC(C)=O.Cc1ccc(Br)c(N)n1>>CC(=O)Nc1nc(C)ccc1Br,,C1COCCO1,,,,test
US06057369,COc1ccc(S[C@H](CCCCc2ccccc2)[C@H](C)C(=O)O)cc1OC.C[Si](C)(C)ON>>COc1ccc(S[C@H](CCCCc2ccccc2)[C@H](C)C(=O)NO)cc1OC,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US05210092,CCCCc1nc2cccnc2n1Cc1ccc(-c2cc(Cl)sc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCCc1nc2cccnc2n1Cc1ccc(-c2cc(Cl)sc2-c2nnn[nH]2)cc1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20050222261A1,CC(=O)O.NCc1ccc(F)cc1>>CC(=O)NCc1ccc(F)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US03959362,CC(N)=S.O=S1(=O)CCCO1>>O=S(=O)([O-])CCCS.[NH4+],,CO,,,,test
US20140275085A1,CC(C)N.COc1nc(SC)ncc1-c1ccc(Oc2ccnc(-c3cnn(C)c3)c2)c(C)n1>>COc1nc(NC(C)C)ncc1-c1ccc(Oc2ccnc(-c3cnn(C)c3)c2)c(C)n1,,ClCCl,,O=C(OO)c1cccc(Cl)c1,,test
US20050165050A1,COc1ccc(F)cc1C(C)(C)CC(O)(C=Nc1cccc2nc(COC(C)=O)ccc12)C(F)(F)F>>COc1ccc(F)cc1C(C)(C)CC(O)(CNc1cccc2nc(COC(C)=O)ccc12)C(F)(F)F,,C1CCOC1,CO,O,[BH4-].[Na+],test
US20070082908A1,COC(=O)CC(=O)C(=NO)C(=O)OC.Cl>>COC(=O)CC(=O)[C@H](N)C(=O)OC.Cl,[Pd],CO,,O,,test
US20100010007A1,CS(=O)(=O)c1ccc(Cn2ccn(C3CCN(Cc4ccccc4)CC3)c2=O)cc1>>CS(=O)(=O)c1ccc(CN2CCN(C3CCNCC3)C2=O)cc1,[Pd],CCO,,,,test
US20110092540A1,Nc1ccc2c(c1)C(=O)CC2.O=S(=O)(Cl)c1c(Cl)nc2n1CCS2>>O=C1CCc2ccc(NS(=O)(=O)c3c(Cl)nc4n3CCS4)cc21,,CC#N,,O=C([O-])O.[Na+],,test
US20110105544A1,COC(=O)C(CCCc1ccccc1)CCc1ccc(O)cc1.N#Cc1cccc(F)c1>>COC(=O)C(CCCc1ccccc1)CCc1ccc(Oc2cccc(C#N)c2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US03962223,CC(C)C1=C(C(=O)[O-])N2C(=O)[C@H](NC(=O)Cc3ccc([N+](=O)[O-])cc3)[C@H]2SC1>>CC(C)C1=C(C(=O)O)N2C(=O)[C@H](NC(=O)Cc3ccc([N+](=O)[O-])cc3)[C@H]2SC1,,O=C(O)C(F)(F)F,,,,test
US09242937B2,COc1ccccc1-c1ccnc(Cl)c1.Nc1cccc(CS(N)(=O)=O)c1>>COc1ccccc1-c1ccnc(Nc2cccc(CS(N)(=O)=O)c2)c1,,CN(C)C=O,,,,test
US20100166699A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.N#Cc1ccc(C2(c3ccc(Cl)cc3)CCNCC2)cc1>>N#Cc1ccc(C2(c3ccc(-c4cn[nH]c4)cc3)CCNCC2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US04808729,CCOC(=O)CCC(C)=O.OCC(S)CS>>CCOC(=O)CCC1(C)OCC(CS)S1,,ClCCl,,CCOCC,FB(F)F,test
US20040259884A1,COS(=O)(=O)C(F)(F)F.Cc1nccn1S(=O)(=O)N1CCN(C(=O)OC(C)(C)C)CC1>>Cc1nccn1S(=O)(=O)N1CCN(C(=O)OC(C)(C)C)CC1.O=S(=O)(O)C(F)(F)F,,ClCCl,,,,test
US20100113514A1,N#CCBr.O=C1CCc2cc(-c3ccc(C(F)(F)F)cc3)ccc2N1>>N#CCN1C(=O)CCc2cc(-c3ccc(C(F)(F)F)cc3)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20050054678A1,CC1(N)CCNCC1.Clc1ncccn1>>CC1(N)CCN(c2ncccn2)CC1,,O,,CCO,O=C([O-])[O-].[K+].[K+],test
US20130023541A1,CC(C)OC(=O)c1cccnc1N1CCN(Cc2ccccc2C=O)CC1.CCNCc1c(F)cccc1Cl>>CCN(Cc1ccccc1CN1CCN(c2ncccc2C(=O)OC(C)C)CC1)Cc1c(F)cccc1Cl,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090163546A1,CCOC(=O)Cn1[nH]c(=O)c2cc([N+](=O)[O-])ccc21.CCc1ccccc1N=C=O>>CCOC(=O)Cn1[nH]c(=O)c2cc(NC(=O)Nc3ccccc3CC)ccc21,[Pd],CCO,CCOC(C)=O,O,[H][H],test
US20090186909A1,Cc1cccc(C)c1Br.O=Cc1ccc(F)c(B(O)O)c1>>Cc1cccc(C)c1-c1cc(C=O)ccc1F,,Cc1ccccc1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US05750754,CCOC(=O)N1CCN(c2cn(Cc3ccccc3)c3cc(OC)ccc3c2=O)CC1>>COc1ccc2c(=O)c(N3CCNCC3)cn(Cc3ccccc3)c2c1,,CCO,,[K+].[OH-],,test
US20050131038A1,CCCCC(=O)N1C(c2ccc(-c3ccccc3C#N)cc2)OC(=O)C1C(C)C>>CCCCC(=O)N(Cc1ccc(-c2ccccc2C#N)cc1)C(C(=O)O)C(C)C,[Pd],CCO,,O=C[O-].[NH4+],,test
US20100105906A1,Fc1ccc2c(c1)CCCN2.O=C(O)c1cccnc1Oc1cc(Cl)ccc1Cl>>O=C(c1cccnc1Oc1cc(Cl)ccc1Cl)N1CCCc2cc(F)ccc21,,ClCCl,,CCN(CC)CC,C[n+]1ccccc1Cl.[I-],test
US05378726,BrBr.Cc1cccc2c1OCCO2>>Cc1c(Br)ccc2c1OCCO2,,CC(=O)O,,O=S([O-])O.[Na+],,test
US04678502,CC(C)(C)NS(=O)(=O)c1ccccc1CCBr>>NS(=O)(=O)c1ccccc1CCBr,,O=C(O)C(F)(F)F,,,,test
US20030087926A1,CC=Cc1ccc(OC)cc1.CCC(=O)C(=O)[O-].Nc1cc(Cl)cc(Cl)c1>>CCOC(=O)C1Nc2cc(Cl)cc(Cl)c2C(c2ccc(OC)cc2)C1C,,CC#N,,O=C(O)C(F)(F)F,,test
US20160264578A1,COc1cccc(-n2c(=O)c3c(C)c(-c4ccc([N+](=O)[O-])cc4)cn3n(Cc3c(F)cccc3F)c2=O)c1F.O=C1CCC(=O)N1Br>>COc1cccc(-n2c(=O)c3c(CBr)c(-c4ccc([N+](=O)[O-])cc4)cn3n(Cc3c(F)cccc3F)c2=O)c1F,,Clc1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20130178459A1,COc1cc(C)c2c(c1-c1ccc([C@@H](C)CNC(=O)OC(C)(C)C)cc1)c1cc(F)sc1c(=O)n2COCC[Si](C)(C)C>>Cc1cc(O)c(-c2ccc([C@@H](C)CN)cc2)c2c1[nH]c(=O)c1sc(F)cc12,,ClCCl,,BrB(Br)Br,,test
US06359134B1,O=C(Nc1ccc2ccc(S(=O)(=O)N3CCN(C(=O)c4ccc(-n5ccnc5)cc4)CC3)cc2c1)OCC(Cl)(Cl)Cl>>Nc1ccc2ccc(S(=O)(=O)N3CCN(C(=O)c4ccc(-n5ccnc5)cc4)CC3)cc2c1,[Zn],CC(=O)O,,,,test
US05449677,CC(C)Oc1ccccc1N1CCCCC1.ClCc1cccc(CCl)c1>>CC(C)Oc1ccccc1N1CCC(Cc2cccc(CCl)c2)CC1,,O,,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US20140274702A1,COC(=O)c1nc(-c2ccc3nonc3c2)c(F)c(N)c1Cl>>Nc1c(F)c(-c2ccc3nonc3c2)nc(C(=O)O)c1Cl,,CO,,Cl,[Na+].[OH-],test
US20140179715A1,CC(C)(C)OC(=O)N1CCn2c1cc(OCc1ccc(Oc3ccc(Cl)c(C(F)(F)F)c3)c(C#N)c1)nc2=O>>N#Cc1cc(COc2cc3n(c(=O)n2)CCN3)ccc1Oc1ccc(Cl)c(C(F)(F)F)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060041090A1,CCCCB(CCCC)CCCC.O=O>>CCCCB(CCCC)CCCC.O=O,,ClCCl,,,,test
US20130324724A1,CCCn1c(NC(=O)c2ccc(Cl)nc2)c(N=O)c(=O)n(C2CC2)c1=O>>CCCn1c(=O)n(C2CC2)c(=O)c2[nH]c(-c3ccc(Cl)nc3)nc21,,CS(C)=O,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US03948906,O=C(Cc1cccs1)N[C@@H]1C(=O)N2C(C(=O)O)=C(COC(=O)C(Cl)Cl)CS[C@H]12.c1cn[nH]c1>>O=C(Cc1cccs1)N[C@@H]1C(=O)N2C(C(=O)O)=C(Cn3cccn3)CS[C@H]12,,CC(C)=O,,,,test
US20040116467A1,CN(C)N.O=C1CCCCC1Cc1ccc(Br)cc1>>CN(C)N=C1CCCCC1Cc1ccc(Br)cc1,,CCO,,,,test
US04695648,CC(=O)Cl.COC(=O)Cc1ccccc1OC>>COC(=O)Cc1cc(C(C)=O)ccc1O,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20070244159A1,CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc2[nH]1.CO.ClCC1CO1>>COCC(O)Cn1c(C(C)(C)C)cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc21,,CN(C)C=O,CO,C1CCOC1,[H-].[Na+],test
US20100152160A1,CC(C)(C)OC(=O)N1CC(C(=O)N2CCC(C#N)(Cc3ccc(F)cc3)CC2)Oc2cc(Cl)c(O)cc21.CI>>COc1cc2c(cc1Cl)OC(C(=O)N1CCC(C#N)(Cc3ccc(F)cc3)CC1)CN2C(=O)OC(C)(C)C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05556864,COc1cccc(CCc2ccccc2OC2CCN(C)CC2)c1.Cl>>COc1cccc(CCc2ccccc2OC2CCN(C)CC2)c1.Cl,,C1COCCO1,CCOC(C)=O,,,test
US06583299B1,CCCCC(=O)N[C@@H](CS(=O)(=O)c1ccc(Sc2ccccc2)cc1)C(=O)O.NOC1CCCCO1>>CCCCC(=O)NC(CS(=O)(=O)c1ccc(Sc2ccccc2)cc1)C(=O)NOC1CCCCO1,,C1CCOC1,,ClCCCl,On1nnc2ccccc21,test
US20080085890A1,CC1(C)NC(=O)Cc2cc(Br)ccc21.CN1CCN(c2ccc(N)cc2)CC1.COC(OC)N(C)C>>CN1CCN(c2ccc(NC=C3C(=O)NC(C)(C)c4ccc(Br)cc43)cc2)CC1,,CN(C)C=O,Cc1ccccc1,,,test
US20040248913A1,Cc1cc(=O)oc2c(C(C)C)nc(C(C)C)cc12>>C/C(=C/CO)c1cc(C(C)C)nc(C(C)C)c1O,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05166155,O=C(CBr)OCc1ccccc1.O=c1cnc2cc(Cl)c(Cl)cc2[nH]1>>O=C(Cn1c(=O)cnc2cc(Cl)c(Cl)cc21)OCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20150266874A1,CC(C)N.CCOC(=O)c1c[nH]nc1-c1nc2ccccc2[nH]1>>CC(C)NC(=O)c1c[nH]nc1-c1nc2ccccc2[nH]1,,O,,C[Al](C)C,,test
US20100234351A1,CC(C)(C)OC(=O)NCCS(=O)(=O)C(C)(C)CO.Cl>>CC(C)(CO)S(=O)(=O)CCN.Cl,,C1CCOC1,,,,test
US05359067,Cc1c[nH]c(=O)nc1-n1cncn1>>Cc1c[nH]c(=O)nc1N,,N,,,,test
US20110172219A1,C[C@H]1COc2c(F)c(F)c(N)c3c(=O)c(C#N)cn1c23.NCCCc1cccnc1>>C[C@H]1COc2c(NCCCc3cccnc3)c(F)c(N)c3c(=O)c(C#N)cn1c23,,CS(C)=O,,,,test
US20110190342A1,N[C@@H](Cc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)C(=O)O.O=C(O)c1cc2cc(Cl)ccc2nc1Cl>>O=C(O)c1cc2cc(Cl)ccc2nc1N[C@@H](Cc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)C(=O)O,,CS(C)=O,,,,test
US20080234290A1,CC(C)(C)OC(=O)N1CCN(c2cc3c(cc2F)nc(COc2ccccc2)n3Cc2ccc(Cl)cc2)CC1>>Fc1cc2nc(COc3ccccc3)n(Cc3ccc(Cl)cc3)c2cc1N1CCNCC1,,O,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20100190775A1,CCC(=O)Cl.CSc1ncc2c(n1)N1CCC[C@H]1CN(c1cccc(C#N)c1)C2=O.NO>>CCc1nc(-c2cccc(N3C[C@@H]4CCCN4c4nc(SC)ncc4C3=O)c2)no1,,CCO,CCOC(C)=O,CCN(C(C)C)C(C)C,Cl,test
US20100233116A1,CCOC(=O)c1sc(NC(=O)Oc2ccccc2)cc1C.NN>>CCOC(=O)c1sc(NC(=O)NN)cc1C,,C1CCOC1,,O,,test
US20100279936A1,C#CCCCCCl.C[C@@H](N)c1cccc2ccccc12>>C#CCCCCN[C@H](C)c1cccc2ccccc12,,CCOC(C)=O,CN(C)C=O,[I-].[Na+],,test
US06579872B1,C1COCCN1.CCN(CC)Cc1ccc(C(=O)Nc2cc(NC(=O)c3cc(Cl)ccc3[N+](=O)[O-])ccc2C)cc1>>CCN(CC)Cc1ccc(C(=O)Nc2cc(NC(=O)c3cc(N4CCOCC4)ccc3[N+](=O)[O-])ccc2C)cc1,,ClCCl,,,,test
US04692449,CCOC(=O)N1CCNCC1.O=C1C=CC(=O)c2nccnc21>>CCOC(=O)N1CCN(C2=CC(=O)c3nccnc3C2=O)CC1,,C1COCCO1,,,,test
US20100178246A1,CC(C)(C)OC(=O)CC[C@H](NC(=O)N[C@@H](CCCCNC(=O)[C@H](CCCCN(Cc1nccn1CC(=O)OC(C)(C)C)Cc1nccn1CC(=O)OC(C)(C)C)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)CC[C@H](NC(=O)N[C@@H](CCCCNC(=O)[C@@H](N)CCCCN(Cc1nccn1CC(=O)OC(C)(C)C)Cc1nccn1CC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,CN(C)C=O,,C1CCNCC1,,test
US20100286152A1,COC(=O)C(=O)C(C)(c1ccc2c(c1)OCO2)N1CCN(C)CC1>>CN1CCN(C(C)(C(=O)C(=O)O)c2ccc3c(c2)OCO3)CC1,,CO,O,Cl,[Li+].[OH-],test
US20070269664A1,COc1ccc(CCOn2c(C)nc3c(C)cccc32)cc1>>Cc1cccc2c1nc(C)n2OCCc1ccc(O)cc1,,ClC(Cl)Cl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20130023566A1,CCOC(OCC)c1ccccc1Br.O=Cc1ccc(Br)cc1F>>CCOC(OCC)c1ccccc1C(O)c1ccc(Br)cc1F,,CCOCC,,[Li]CCCC,,test
US20160075713A1,CCOC(=O)C(F)(F)c1ccc(C(F)F)cn1>>OCC(F)(F)c1ccc(C(F)F)cn1,,CCO,,[BH4-].[Na+],,test
US20150307489A1,CC(=O)OC(C)=O.COc1ccc([C@H]2C[C@@H]2COc2nc(C)ncc2-c2ccc(C(N)=NO)cc2)nc1>>COc1ccc([C@H]2C[C@@H]2COc2nc(C)ncc2-c2ccc(-c3noc(C)n3)cc2)nc1,,C1CCOC1,,CC(=O)O,O,test
US20090105257A1,CC(C)N.Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CNc1ccc([C@@H]2C[C@H]2C(=O)O)cc1>>Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CNc1ccc(C2CC2C(=O)NC(C)C)cc1,,CN(C)C=O,ClCCl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20030125370A1,Cc1[nH]c(C=O)c(C)c1C(=O)N1CCN(C)CC1.N#Cc1ccccc1CS(=O)(=O)c1ccc2c(c1)CC(=O)N2>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4ccccc4C#N)cc32)c(C)c1C(=O)N1CCN(C)CC1,,CCO,,C1CCNCC1,,test
US20060025415A1,CCOC(=O)CCCOc1ccc(Cl)cc1Cl>>O=C(O)CCCOc1ccc(Cl)cc1Cl,,C1CCOC1,O,[Li]O,,test
US20160151387A1,BrCc1ccccc1.O=C(O)[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O>>O=C(OCc1ccccc1)[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O,,CN(C)C=O,,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20110190235A1,C=C[Sn](CCCC)(CCCC)CCCC.COC(=O)c1ccc(Br)cc1Cl>>C=Cc1ccc(C(=O)O)c(Cl)c1,,C1CCOC1,,,,test
US20050234101A1,ClCc1ccccc1.FC(F)(F)c1ccncc1>>FC(F)(F)c1cc[n+](Cc2ccccc2)cc1.[Cl-],,CC#N,,COC(C)(C)C,,test
US20050171087A1,Nc1cc2c(cc1Cl)N1CCC[C@@H](NC(=O)C(F)(F)F)[C@H]1c1ccccc1O2.O=S(=O)(Cl)c1ccccc1>>O=C(N[C@@H]1CCCN2c3cc(Cl)c(NS(=O)(=O)c4ccccc4)cc3Oc3ccccc3[C@H]12)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20150336935A1,COc1cc(OC)cc(C(O)[C@@H]2[C@@]3(C)CCCC(C)(C)[C@@H]3CC[C@@]2(C)O)c1>>COc1cc(OC)cc(C(=O)[C@@H]2[C@@]3(C)CCCC(C)(C)[C@@H]3CC[C@@]2(C)O)c1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20100093751A1,CCOC(=O)Cc1c(C)c(Sc2ccc(S(=O)(=O)N3CCNCC3)cc2)n2cc(C#N)ccc12>>Cc1c(CC(=O)O)c2ccc(C#N)cn2c1Sc1ccc(S(=O)(=O)N2CCNCC2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20150291563A1,Fc1ccc(N2N=C(C(F)(F)C(F)(F)F)CC2c2cccc(Br)c2)c(F)c1.OB(O)c1ccccc1>>Fc1ccc(N2N=C(C(F)(F)C(F)(F)F)CC2c2cccc(-c3ccccc3)c2)c(F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20130101667A1,CC(CNC1CCCCC1)OC(=O)c1ccccc1.CCI>>CCN(CC(C)OC(=O)c1ccccc1)C1CCCCC1,,ClCCCl,,O=C([O-])[O-].[K+].[K+],,test
US20110118261A1,Brc1ccc(Br)nc1.OC1CCNC1>>OC1CCN(c2ccc(Br)cn2)C1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20080287479A1,CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3cc(-c4noc(=O)[nH]4)ccc32)CC1.O=C(CBr)c1ccc(Cl)cc1>>O=C(CN1CCC(n2c(=O)[nH]c3cc(-c4noc(=O)[nH]4)ccc32)CC1)c1ccc(Cl)cc1,,CN(C)C=O,ClCCl,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20080139556A1,CON(C)C(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1>>O=C[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140315881A1,CCOC(=O)Cc1ccc(NC(=O)c2c(C)noc2C)c([N+](=O)[O-])c1>>CCOC(=O)Cc1ccc2nc(-c3c(C)noc3C)[nH]c2c1,[Zn],CC(=O)O,,,,test
US20100324069A1,COC(=O)c1cc(I)cc(-c2ccc(C)cc2)c1>>Cc1ccc(-c2cc(I)cc(C(=O)O)c2)cc1,,CO,,Cl,[Na+].[OH-],test
US05637729,CC(=O)Cl.CSC1=NC(C)(c2ccccc2)C(=O)N1Nc1ccccc1>>CSC1=NC(C)(c2ccccc2)C(=O)N1N(C(C)=O)c1ccccc1,,C1CCOC1,,O,CC(C)(C)[O-].[K+],test
US20150232445A1,COCOc1cccc2c1CC[C@H](C)N2C(C)=O>>CC(=O)N1c2cccc(O)c2CC[C@@H]1C,,CO,,Cl,,test
US20040038993A1,CCOC(=O)c1cnn2c(C3CCCCC3)c(-c3ccc(I)cc3)cnc12.c1ccc(CB2C3CCCC2CCC3)cc1>>CCOC(=O)c1cnn2c(C3CCCCC3)c(-c3ccc(Cc4ccccc4)cc3)cnc12,[Pd],C1CCOC1,CCOC(C)=O,[Na+].[OH-],,test
US20060148858A1,CCOC(=O)CCc1c(O)cccc1OC.CCOc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO>>CCOc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCOc1cccc(OC)c1CCC(=O)O,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US04885373,NC1CCc2cc3c(cc2C1)OCC3.O=Cc1ccccc1>>c1ccc(CNC2CCc3cc4c(cc3C2)OCC4)cc1,,c1ccccc1,,Cl,,test
US20050054715A1,CC(=O)OC(C)=O.COC(=O)c1ccc(C)nc1.CSc1ccc(O)c(C=O)c1>>COC(=O)c1ccc(/C=C/c2cc(SC)ccc2OC(C)=O)nc1,,CC(=O)OC(C)=O,,CC(=O)O,O,test
US20150284367A1,COc1ccc(Nc2cc(Cl)nnc2C(N)=O)nc1C(C)C.NCCN>>COc1ccc(Nc2cc(NCCN)nnc2C(N)=O)nc1C(C)C,,CN1CCCC1=O,,,,test
US04746352,Cc1cc(=O)n(-c2cc(C(=O)OC(C)C)c(Cl)cc2F)c(=O)n1C.O=S(=O)(Cl)Cl>>Cc1c(Cl)c(=O)n(-c2cc(C(=O)OC(C)C)c(Cl)cc2F)c(=O)n1C,,CC(=O)O,,,,test
US05175166,CCCCCCCCC(N)=NO.COC(=O)C1CN=CN(C(c2ccccc2)(c2ccccc2)c2ccccc2)C1>>CCCCCCCCc1noc(C2CN=CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)C2)n1,,C1CCOC1,,[H-].[Na+],,test
US20020052344A1,CC(=N)NO.COC(Cc1ccc(C(=O)O)cc1)(OC)c1ccccc1>>Cc1noc(-c2ccc(CC(=O)c3ccccc3)cc2)n1,,CN(C)C=O,O,O=C(n1ccnc1)n1ccnc1,,test
US20140018319A1,CC(C)(C)OC(=O)Nc1cccc(C#N)n1>>N#Cc1cccc(N)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US03933836,BrCc1ccccc1.Nc1ccccn1>>Nc1cccc[n+]1Cc1ccccc1.[Br-],,Cc1ccccc1C,,,,test
US20030130340A1,COc1cccc(SCC(=O)c2ccccn2)c1>>COc1ccc2c(-c3ccccn3)csc2c1,,O,,[Na+].[OH-],,test
US20110207731A1,CC1=C(C#N)C(c2ccc3c(c2)c(N)nn3C(=O)OC(C)(C)C)C(C#N)=C(C)N1.O=S(=O)(Cl)Cc1ccc(F)cc1>>CC1=C(C#N)C(c2ccc3c(c2)c(NS(=O)(=O)Cc2ccc(F)cc2)nn3C(=O)OC(C)(C)C)C(C#N)=C(C)N1,,ClCCl,,CCN(CC)CC,,test
US20070049618A1,CCOc1cc(Nc2cccc(C(=O)O)c2C(=O)O)ccc1OC.NC1CCC(=O)NC1=O>>CCOc1cc(Nc2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)ccc1OC,,c1ccncc1,,Cl,,test
US20090029958A1,CC(C)(C)[Si](C)(C)O[C@@H](CN)c1ccc(O)c2[nH]c(=O)ccc12.Clc1cccc(Cl)c1CCOCCN1CCC2(CC1)CO2>>CC(C)(C)[Si](C)(C)O[C@@H](CNCC1(O)CCN(CCOCCc2c(Cl)cccc2Cl)CC1)c1ccc(O)c2[nH]c(=O)ccc12,,CO,,,,test
US20120071467A1,CN(CCCO)C(=O)OC(C)(C)C.NC1CC1>>CN(CCCNC1CC1)C(=O)OC(C)(C)C,,CCOC(C)=O,CO,CCN(CC)CC,CS(=O)(=O)Cl,test
US20130143907A1,COc1ccc(Cn2c(=O)c3cnn(C4CCOCC4)c3c3ccc(-c4c(C)cccc4C)cc32)c(OC)c1>>Cc1cccc(C)c1-c1ccc2c(c1)[nH]c(=O)c1cnn(C3CCOCC3)c12,,O=C(O)C(F)(F)F,,,,test
US20070191447A1,O=C1COc2cc(Br)cc([N+](=O)[O-])c2N1.OB(O)Oc1ccccc1>>Nc1c(OCC(=O)O)cc(-c2ccccc2)cc1[N+](=O)[O-],,ClC(Cl)Cl,O,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20110263584A1,CC(C)(O)c1ccc(Cl)nn1.C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O>>C[C@@H](c1ccc(-c2ccc(C(C)(C)O)nn2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04665202,COC1=CC(c2ccccc2)Oc2ccccc21.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COC1=C(C(=O)C(F)(F)F)C(c2ccccc2)Oc2ccccc21,,ClCCl,,c1ccncc1,,test
US20070105904A1,BrCc1ccc(Br)cc1.Nc1ncccc1-c1cn[nH]c1>>Nc1ncccc1-c1cnn(Cc2ccc(Br)cc2)c1,,CN(C)C=O,O,C1CCOC1,[H-].[Na+],test
US05034417,CS(=O)(=O)Nc1ccc(C#N)cc1Sc1ccc(F)cc1F.O=CO>>CS(=O)(=O)Nc1ccc(C=O)cc1Sc1ccc(F)cc1F,[Ni],,,,,test
US20100331293A1,NC(=O)c1ncc(N2CCOCC2)cc1N>>N#Cc1ncc(N2CCOCC2)cc1N,,CC#N,,O=P(Cl)(Cl)Cl,,test
US20110163302A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1ccc(N(c2cccc3c2sc2ccccc23)c2cccc3c2sc2ccccc23)cc1>>O=S(=O)(Oc1ccc(N(c2cccc3c2sc2ccccc23)c2cccc3c2sc2ccccc23)cc1)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US20060014826A1,O=C1CSCC(=O)C1.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>O=C1CSCC(=O)C1C(=O)Nc1ccc(Cl)c(C(F)(F)F)c1,,CC#N,O,O=P(O)(O)O,,test
US20090082423A1,CC1(C)CC(N)CC(C)(C)C1=O.O=C=Nc1ccc(C(F)(F)F)cc1>>CC1(C)CC(NC(=O)Nc2ccc(C(F)(F)F)cc2)CC(C)(C)C1=O,,ClC(Cl)Cl,,O,,test
US04482729,COC(=O)C(C(F)(F)F)C(F)(F)F>>COC(=O)CC(F)(F)F,,O,,CC(=O)[O-].[K+],,test
US20070021426A1,CCOC(=O)COC(=O)Oc1ccccc1.NCCc1ccc(-c2ccccc2)nc1>>CCOC(=O)COC(=O)NCCc1ccc(-c2ccccc2)nc1,,Cc1ccccc1,,,,test
US20060052374A1,CCCC[Sn](CCCC)(CCCC)c1cccs1.N#Cc1cccnc1Cl>>N#Cc1cccnc1-c1cccs1,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,CCOC(C)=O,,[Cs+].[F-],,test
US20130196974A1,Cc1ccccc1.O=C1CCNCc2ccccc21.O=c1[nH]c(Cl)nc2ccccc12>>Cc1ccc2nc(N3CCC(=O)c4ccccc4C3)nc(O)c2c1,,Cc1ccccc1,,CCN(CC)CC,,test
US20090233924A1,COc1cc2ncnc(Oc3ccc(CC(=O)O)cc3)c2cc1OC.COc1cccc(N)c1>>COc1cccc(NC(=O)Cc2ccc(Oc3ncnc4cc(OC)c(OC)cc34)cc2)c1,,O,,CCN(C(C)C)C(C)C,CN(C)C=O,test
US20020072516A1,CCOC(C)=O.CCc1cc(C[C@H](NC(C)=O)C(=O)O)ccc1N(C(=O)C(=O)OCc1ccccc1)c1ccccc1C(=O)OC(c1ccccc1)c1ccccc1.COC(=O)c1c(O)cccc1OCCCCN>>CCc1cc(CC(NC(C)=O)C(=O)NCCCCCOc2cccc(O)c2C(=O)OC)ccc1N(C(=O)C(=O)OCc1ccccc1)c1ccccc1C(=O)OC(c1ccccc1)c1ccccc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US04282361,Cc1n[nH]c(C(N)=O)c1NC=O>>Cc1n[nH]c2c(O)ncnc12,,CN(C)C=O,,C[O-].[Na+],,test
US20090137580A1,Cn1c(C(C)(C)O[Si](C)(C)C)cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(Cl)c3)c21>>Cn1c(C(C)(C)O)cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(Cl)c3)c21,,CCO,,Cl,,test
US05157038,C#CC1(OC(=O)NCc2ccccc2)CCN(Cc2ccccc2)CC1>>C=C1N(Cc2ccccc2)C(=O)OC12CCN(Cc1ccccc1)CC2,,CO,,C[O-].[Na+],,test
US05679671,CC(O)=S.O=C(OC(c1ccccc1)c1ccccc1)C(O)Cc1ccc(F)cc1>>CC(=O)SC(Cc1ccc(F)cc1)C(=O)OC(c1ccccc1)c1ccccc1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040067966A1,CCCn1c(=O)c2[nH]c(C34CCC(C(=O)O)(CC3)CC4)nc2n(CCC)c1=O.N>>CCCn1c(=O)c2[nH]c(C34CCC(C(N)=O)(CC3)CC4)nc2n(CCC)c1=O,,C1COCCO1,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100029636A1,CCCCOC(=O)Cl.Nc1ccc(-c2cnc3c(-c4cccc(N5CCN(C(=O)OCc6ccccc6)CC5)c4)cnn3c2N)cc1>>CCCCOC(=O)Nc1ccc(-c2cnc3c(-c4cccc(N5CCN(C(=O)OCc6ccccc6)CC5)c4)cnn3c2N)cc1,,CN1CCCC1=O,,CCOC(C)=O,O=C([O-])O.[Na+],test
US20080015187A1,COC(=O)c1nn2c(c1OCc1ccccc1)C(=O)NCCC2>>O=C(O)c1nn2c(c1OCc1ccccc1)C(=O)NCCC2,,CO,,Cl,[Na+].[OH-],test
US20100305133A1,CCOC(=O)CNC(=O)c1c(O)ccc2[nH]c(=O)c(-c3ccccc3)nc12>>O=C(O)CNC(=O)c1c(O)ccc2[nH]c(=O)c(-c3ccccc3)nc12,,CCO,,[Na+].[OH-],,test
US20100168113A1,COc1cc(C(=O)O)cc([N+](=O)[O-])c1O.Cc1nc(Cl)c(/C(N)=N/O)c(C)c1Cl>>COc1cc(-c2nc(-c3c(Cl)nc(C)c(Cl)c3C)no2)cc([N+](=O)[O-])c1O,,O=S(Cl)Cl,,Cl,c1ccncc1,test
US20040259912A1,COC(=O)c1cc(N)ccc1OC(c1ccccc1)c1ccc(Cl)cc1Cl.COc1ccc(N=C=O)cc1OC>>COC(=O)c1cc(NC(=O)Nc2ccc(OC)c(OC)c2)ccc1OC(c1ccccc1)c1ccc(Cl)cc1Cl,,C1CCOC1,,,,test
US20070197577A1,CC(C)(C)OC(=O)N[C@@H](CC(=O)NOCc1ccccc1)Cc1c(F)c(F)c(F)c(F)c1F>>N[C@@H](CC(=O)NOCc1ccccc1)Cc1c(F)c(F)c(F)c(F)c1F,,C1COCCO1,Cl,,,test
US20120088753A1,CN1CCCN(c2ccc([N+](=O)[O-])cn2)CC1>>CN1CCCN(c2ccc(N)cn2)CC1,[Pd],CCO,,,,test
US20040214841A1,COC(=O)c1c(N)cc(OCc2ccccc2)cc1OCc1ccccc1.N=CN>>O=c1[nH]cnc2cc(OCc3ccccc3)cc(OCc3ccccc3)c12,,COCCO,,CC(=O)O,,test
US20070112005A1,CC(C)(C)OC(=O)n1c(B(O)O)cc2ccccc21.NC(=O)[C@@H]1CC[C@@H](c2nc(I)c3c(N)nccn23)CC1>>NC(=O)[C@@H]1CC[C@@H](c2nc(-c3cc4ccccc4[nH]3)c3c(N)nccn23)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US06177459B1,CN(C#N)c1ccccc1CBr.Cc1ccccc1O>>Cc1ccccc1OCc1ccccc1N(C)C#N,,CN(C)C=O,,[H-].[Na+],,test
US20110046160A1,CC(C)Oc1cccc(CN2CC[C@]3(CNS(=O)(=O)N3c3cccc(F)c3)C[C@@H]2C)c1.CI>>CC(C)Oc1cccc(CN2CC[C@@]3(C[C@@H]2C)CN(C)S(=O)(=O)N3c2cccc(F)c2)c1,,CN(C)C=O,O,[H-].[Na+],,test
US20100286181A1,CC(C)(C)OC(=O)N1CC[C@H](N)[C@H](N=[N+]=[N-])C1.Cc1[nH]c(C(=O)Cl)c(Cl)c1Cl>>Cc1[nH]c(C(=O)N[C@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2N=[N+]=[N-])c(Cl)c1Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05595989,Br[Mg]C1CC1.O=C1c2ccccc2CCc2ccccc21>>OC1(C2CC2)c2ccccc2CCc2ccccc21,,C1CCOC1,,Cl,[Cl-].[NH4+],test
US20090036450A1,CCN(CC)S(=O)(=O)c1ccsc1CCl.[N-]=[N+]=[N-]>>CCN(CC)S(=O)(=O)c1ccsc1CN=[N+]=[N-],,CN(C)C=O,,O,,test
US20040092737A1,CC(=O)OC(C)=O.COCN1c2cc(N)ccc2Sc2nccnc21>>COCN1c2cc(NC(C)=O)ccc2Sc2nccnc21,,CCOC(C)=O,,,,test
US20160046618A1,CC(C)(C)[S@@](=O)N[C@@](C)(CCO)c1cc(Br)ccc1F>>CC(C)(C)[S@@](=O)N[C@@](C)(CC=O)c1cc(Br)ccc1F,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20130116285A1,COc1ncccc1-c1cc(C#N)ccc1Oc1ccccc1.OO>>COc1ncccc1-c1cc(C(N)=O)ccc1Oc1ccccc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090163662A1,CCCCCCCCCCN(C)CCCCCCCCCC.CO.COC(=O)OC>>CCCCCCCCCC[N+](C)(C)CCCCCCCCCC.COC(=O)[O-],,CO,,,,test
US05556864,COc1cccc(CCc2ccccc2OCC[C@@H]2C[C@@H](O)CN2C)c1.Cl>>COc1cccc(CCc2ccccc2OCC[C@@H]2C[C@@H](O)CN2C)c1.Cl,,C1COCCO1,,,,test
US20070213376A1,C[Si](C)(C)C=[N+]=[N-].Cl.O=C(Cl)c1cccc(F)n1>>O=C(CCl)c1cccc(F)n1,,C1COCCO1,,,,test
US06858739B2,COc1ccc(-c2cc3ccccc3[nH]2)cc1N.S=C=Nc1cc(Cl)cc(Cl)c1>>COc1ccc(-c2cc3ccccc3[nH]2)cc1NC(=S)Nc1cc(Cl)cc(Cl)c1,,CCOC(C)=O,,,,test
US20130079313A1,COc1ccc(C(=O)O)cc1N.OCc1ccccc1>>COc1ccc(C(=O)OCc2ccccc2)cc1N,CN(C)c1ccncc1,CN(C)C=O,,ClCCCl,,test
US05028254,COC(=O)C1CCC(C)C1=O.ClCc1ccc(Cl)cc1>>CC1CCC(Cc2ccc(Cl)cc2)C1=O,,c1ccccc1,,[H-].[Na+],,test
US20060205792A1,O=[N+]([O-])c1cc(O)ccc1/C=C/c1ccc(O)cc1>>Nc1cc(O)ccc1/C=C/c1ccc(O)cc1,[Zn],CC(C)=O,O,[Cl-].[NH4+],,test
US20090111860A1,CCc1c(C(Cc2ccccc2)NC(=O)OC(C)(C)C)nn(C)c1N.CI.CN(C)C=O>>CCc1c(C(C)NC(=O)OC(C)(C)C)n[nH]c1OC,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110021487A1,N#CC(C#N)=Cc1ccc(O[C@@H]2COC[C@H]2O)cc1.N#CCC(N)=S>>N#Cc1c(N)nc(S)c(C#N)c1-c1ccc(O[C@@H]2COC[C@H]2O)cc1,,CCO,,CN1CCOCC1,,test
US06284902B1,CC(=O)O[C@H](CBr)CC(=O)O.CC(C)NC(C)C>>CC(C)NC(C)C.O=C(O)C[C@H]1CO1,,O,,,,test
US20100216788A1,CC(C)(C)NC(=O)c1cccc(Oc2ccc(N)cc2Cl)c1.Cn1c(Cl)cc2ncnc(Cl)c21>>Cn1c(Cl)cc2ncnc(Nc3ccc(Oc4cccc(C(=O)NC(C)(C)C)c4)c(Cl)c3)c21,,CC(C)O,,,,test
US20090221608A1,CSc1nccc(-c2cn(C3CCCCO3)nc2-c2cnc3[nH]ccc3c2)n1.O=S(=O)(Cl)c1ccccc1>>CSc1nccc(-c2cn(C3CCCCO3)nc2-c2cnc3c(ccn3S(=O)(=O)c3ccccc3)c2)n1,,CN(C)C=O,,[H-].[Na+],,test
US20120094982A1,CC(C)(C)OC(=O)NC(CCc1ccccc1Cl)C(=O)O.Cl>>Cl.NC(CCc1ccccc1Cl)C(=O)O,,Cl,,C1COCCO1,,test
US20060199817A1,Brc1ccc2c(NC3CCCCC3)nncc2c1.Cc1ccc(C(=O)NC2CC2)cc1B1OC(C)(C)C(C)(C)O1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(NC3CCCCC3)nncc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O=C([O-])[O-].[K+].[K+],,test
US06211199B1,COc1cc(C(=O)N2CCC(CCN3CCC(Nc4nc5ccccc5n4Cc4ccc(F)cc4)CC3)(c3ccc(Cl)c(Cl)c3)C2)cc(OC)c1OC.CS(=O)(=O)O>>COc1cc(C(=O)N2CCC(CCN3CCC(Nc4nc5ccccc5n4Cc4ccc(F)cc4)CC3)(c3ccc(Cl)c(Cl)c3)C2)cc(OC)c1OC.CS(=O)(=O)O,,CCOC(C)=O,,,,test
US20120264737A1,COc1ccncc1.C[Mg]Br.O=C(Cl)Oc1ccccc1>>COC1=CC(C)N(C(=O)Oc2ccccc2)C=C1,,C1CCOC1,,,,test
US20160221945A1,O=C1c2ccccc2C(=O)N1Cc1cc(-c2ccc(C3CC3)nc2)ncn1>>NCc1cc(-c2ccc(C3CC3)nc2)ncn1,,CO,,NN,O,test
US20060270688A1,Cc1cccc2c1NCCC2.O=C(Cl)CCl>>Cc1cccc2c1N(C(=O)CCl)CCC2,,ClCCl,,CCN(CC)CC,,test
US20120108582A1,CC(C)(C)OC(=O)N[C@@]12CCOC[C@H]1CNC2.Cc1c(F)ccc2c(=O)c(C(=O)O)cn([C@@H]3C[C@@H]3F)c12>>Cc1c(N2C[C@@H]3COCC[C@@]3(N)C2)ccc2c(=O)c(C(=O)O)cn([C@@H]3C[C@@H]3F)c12,,CCOC(C)=O,CS(C)=O,CCN(CC)CC,,test
US20100105683A1,Cc1ccc(Cl)c([N+](=O)[O-])c1.Oc1ccccn1>>Cc1ccc(Oc2ccccn2)c([N+](=O)[O-])c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04899249,CCNCC.O=S(=O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>CCN(CC)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F,,CCOCC,,,,test
US20070249642A1,COC(CCn1cc(-c2ccc(C)nc2)c(=O)[nH]c1=O)OC>>Cc1ccc(-c2cn(CCC=O)c(=O)[nH]c2=O)cn1,,C1CCOC1,,,,test
US04443365,CCCC(C(=O)OCC)C(=O)OCC.O=C1c2ccccc2C(=O)N1CCCCCBr>>CCCC(CCCCCN1C(=O)c2ccccc2C1=O)(C(=O)OCC)C(=O)OCC,,CCO,,[Na],,test
US20150191483A1,CCN(CC)S(F)(F)F.O=S(=O)(Cc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)c1cccc(Br)c1>>O=S(=O)(Cc1ccc(C(F)(C(F)(F)F)C(F)(F)F)cc1)c1cccc(Br)c1,,CO,,ClCCCl,,test
US08431603B2,CCOCc1cc(OC)c(-c2csc3c(N(CCC4CC4)C4CCOCC4)c(OC)nn23)c(OC)c1.O=P(O)(O)O>>CCOCc1cc(OC)c(-c2csc3c(N(CCC4CC4)C4CCOCC4)c(OC)nn23)c(OC)c1.O=P(O)(O)O,,CCOC(C)=O,,CCO,,test
US20140275080A1,Cc1ncc(-c2cc(Oc3ccc([N+](=O)[O-])nc3)ccn2)n1C>>Cc1ncc(-c2cc(Oc3ccc(N)nc3)ccn2)n1C,[Pd],CO,,,,test
US20150218092A1,COc1cc(N2CC=C(Oc3ccc(C4CC4)cc3)C2=O)ccc1CO[Si](C)(C)C(C)(C)C>>COc1cc(N2CC=C(Oc3ccc(C4CC4)cc3)C2=O)ccc1CO,,C1CCOC1,,Cl,,test
US20100152166A1,COC(=O)c1cn(C)c2cc(C3=CCC(O)CC3)ccc12>>COC(=O)c1cn(C)c2cc(C3CCC(O)CC3)ccc12,[Pd],C1CCOC1,C1CCOC1,,,test
US20060281789A1,C1COCCN1.O=Cc1ccc(F)c([N+](=O)[O-])c1>>O=Cc1ccc(N2CCOCC2)c([N+](=O)[O-])c1,,CCOC(C)=O,O,CCN(C(C)C)C(C)C,ClCCl,test
US20110053948A1,CCOC(=O)C1CCN(c2nnc(C)o2)CC1>>Cc1nnc(N2CCC(C(=O)O)CC2)o1,,CCO,,Cl,[Na+].[OH-],test
US20140296245A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OC[C@@H]1CNCC[C@H]1c1ccc(F)cc1>>CC(C)(C)OC(=O)N1CC[C@@H](c2ccc(F)cc2)[C@H](CO)C1,,ClCCl,,CCN(CC)CC,,test
US20150126471A1,Cc1ccc(S(=O)(=O)OC[C@@H]2CN(C(=O)OC(C)(C)C)CCO2)cc1.Nc1cc(Cl)ncc1C(F)(F)F>>CC(C)(C)OC(=O)N1CCO[C@H](CNc2cc(Cl)ncc2C(F)(F)F)C1,,CN(C)C=O,,[H-].[Na+],,test
US06005117,CC(C)(C)OC(=O)[C@H](CNC(=O)c1ccc(O)cc1)NC(=O)OCc1ccccc1.COC(CBr)OC>>COC(COc1ccc(C(=O)NC[C@H](NC(=O)OCc2ccccc2)C(=O)OC(C)(C)C)cc1)OC,,CN(C)C=O,,[H][H],[H-].[Na+],test
US20050026964A1,Cn1cc(C(=O)O)c(Nc2ccc3ccccc3c2Cl)cc1=O.NOCCO>>Cn1cc(C(=O)NOCCO)c(Nc2ccc3ccccc3c2Cl)cc1=O,,CO,O,COc1nc(OC)nc([N+]2(C)CCOCC2)n1.[Cl-],,test
US20120053174A1,CSc1nc(C(F)(F)c2ccc(F)cn2)nc2cc(Br)ccc12.Cc1cc(N)n[nH]1>>Cc1cc(Nc2nc(C(F)(F)c3ccc(F)cn3)nc3cc(Br)ccc23)n[nH]1,,C1CCOC1,ClCCl,O=C(OO)c1cccc(Cl)c1,,test
US04657842,[N-]=[N+]=NCc1ccc2c(c1)C(=O)c1ccccc1C2=O>>NCc1ccc2c(c1)C(=O)c1ccccc1C2=O,[Pt],CN(C)C=O,,[H][H],,test
US20150133451A1,COC(=O)c1cccc(S(=O)(=O)c2nccs2)c1>>O=C(O)c1cccc(S(=O)(=O)c2nccs2)c1,,CO,,Cl,[Na+].[OH-],test
US20110213003A1,COC(=O)c1ccc(C(C)NC(=O)NC2CCCC2)s1>>CC(NC(=O)NC1CCCC1)c1ccc(C(=O)O)s1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20130109678A1,CCCCN1CCN(c2ccc3[nH]c(-c4ccc(N)c([N+](=O)[O-])c4)nc3c2)CC1>>CCCCN1CCN(c2ccc3[nH]c(-c4ccc(N)c(N)c4)nc3c2)CC1,[Pd],CCOC(C)=O,CO,,,test
US20110039843A1,FC(F)(F)c1ccc2oc(-c3ccncc3I)nc2c1.OB(O)c1cccnc1>>FC(F)(F)c1ccc2oc(-c3ccncc3-c3cccnc3)nc2c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20030087907A1,COc1cc2ncnc(Oc3ccc(N)c(Cl)c3)c2cc1OC.Cc1nc(N)sc1C.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2ncnc(Oc3ccc(NC(=O)Nc4nc(C)c(C)s4)c(Cl)c3)c2cc1OC,,ClC(Cl)Cl,O,CCN(CC)CC,Cl,test
US20160009639A1,COC(=O)c1ccc(CC(C(=O)O)c2ccc(C(C)(C)C)cc2)s1.Nc1ccc(I)cc1>>COC(=O)c1ccc(CC(C(=O)Nc2ccc(I)cc2)c2ccc(C(C)(C)C)cc2)s1,CN(C)c1ccncc1,Cc1ccccc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20120197027A1,CC(C)N.COc1cc2c(Oc3ccc4[nH]c(C)cc4c3)ncnc2cc1OCC1CO1>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3)ncnc2cc1OCC(O)CNC(C)C,,CN(C)C=O,,,,test
US20070232653A1,CCOC(=O)C1=C(c2ccccc2)CN(Cc2ccccc2)C1>>O=C(O)C1=C(c2ccccc2)CN(Cc2ccccc2)C1,,C1COCCO1,,[Na+].[OH-],,test
US20120015941A1,CC(=O)c1csc(NC(=O)NCc2ccc(Cl)c(Cl)c2)n1.CN>>CNC(C)c1csc(NC(=O)NCc2ccc(Cl)c(Cl)c2)n1,,C1CCOC1,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090221606A1,CCO.N#Cc1c[nH]c2c(C(=O)N3CCN(CCc4ccc(F)cc4)CC3)cccc12.O=P(O)(O)O>>N#Cc1c[nH]c2c(C(=O)N3CCN(CCc4ccc(F)cc4)CC3)cccc12.O.O=P(O)(O)O,,CCO,,,,test
US20130287689A1,CC1=Nc2ccccc2C1(C)C.O=C(O)CCCBr>>CC1=[N+](CCCC(=O)O)c2ccccc2C1(C)C.[Br-],,CCOC(C)=O,,,,test
US20150141400A1,CC(C)(C)OC(=O)NC[C@H]1CCCCN1.CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(COS(C)(=O)=O)c(C(F)(F)F)cc2c1=O>>CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(CN3CCCC[C@@H]3CNC(=O)OC(C)(C)C)c(C(F)(F)F)cc2c1=O,,CN(C)C=O,,,,test
US20060235033A1,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.C[C@@H](N)c1cccc(Br)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)N[C@H](C)c4cccc(Br)c4)cc3)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20080312183A1,O=C(c1ccccc1)n1c(=O)ccn(CCCCCNC(c2ccccc2)(c2ccccc2)c2ccccc2)c1=O>>O=c1ccn(CCCCCNC(c2ccccc2)(c2ccccc2)c2ccccc2)c(=O)[nH]1,,CO,,CO[Na],,test
US05604004,CC(C)c1ccc(C=O)cc1.NNc1ccc([N+](=O)[O-])cc1>>CC(C)c1ccc(C=NNc2ccc([N+](=O)[O-])cc2)cc1,,CO,,,,test
US20050176689A1,CC(C)(C)[Si](C)(C)Cl.Cc1cc2c(cc1O)C(C)(C)CCC2=O>>Cc1cc2c(cc1O[Si](C)(C)C(C)(C)C)C(C)(C)CCC2=O,,CN(C)C=O,,O,c1c[nH]cn1,test
US20070112037A1,C=O.CO.COc1ccc(-n2nc(N)cc2-c2ccc(OCCNC(N)=O)cc2)cc1>>COc1ccc(-n2nc(N(C)C)cc2-c2ccc(OCCNC(N)=O)cc2)cc1,,CO,,[BH3-]C#N.[Na+],,test
US20070149577A1,C=CCc1cc(C(C)N)ccc1-c1cc(F)ccc1OC.O=S(=O)(Cl)c1ccc(F)c(F)c1>>C=CCc1cc(C(C)NS(=O)(=O)c2ccc(F)c(F)c2)ccc1-c1cc(F)ccc1OC,,ClCCl,,CCN(CC)CC,,test
US20160264562A1,CCOC(=O)[C@@H](C)OC(=O)C1=C(CN2CCOC[C@H]2C(=O)O)NC(c2nccs2)=N[C@H]1c1ccc(Cl)cc1Cl>>CCOC(=O)C1=C(CN2CCOC[C@H]2C(=O)O)NC(c2nccs2)=N[C@H]1c1ccc(Cl)cc1Cl,,CCO,,[Li],,test
US03989708,CC(=O)C=Cc1ccccc1C.CCOC(=O)CC(=N)N>>CCOC(=O)C1=C(N)NC(C)=CC1c1ccccc1C,,CCO,,CC(C)O,,test
US20160235706A1,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5ccc(Br)cc5C#N)ccc(F)c43)ccc21.Cn1nccc1B1OC(C)(C)C(C)(C)O1>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(Oc5ccc(-c6ccnn6C)cc5C#N)ccc(F)c43)ccc21,,O,,Cc1ccccc1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20060151781A1,CCOC(=O)c1ccc(OCCCCCCOc2cc(F)c(F)c(F)c2)cc1>>O=C(O)c1ccc(OCCCCCCOc2cc(F)c(F)c(F)c2)cc1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20050101586A1,O=C(O)c1csc2c1CCCC2>>OCc1csc2c1CCCC2,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130102776A1,COc1ccc2c(c1/C=C/C1CCN(C(=O)OC(C)(C)C)CC1)OCC2=O.O=Cc1n[nH]c2ccccc12>>COc1ccc2c(c1/C=C/C1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccccc13)C2=O,C1CCNCC1,CO,,,,test
US20120202785A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)Nc1ccc(C#N)cc1Nc1ccccc1>>C[C@H](NC(=O)OC(C)(C)C)c1nc2ccc(C#N)cc2n1-c1ccccc1,,CC(=O)O,,,,test
US20080039491A1,COc1ccc(C(F)(F)F)cc1NC(=O)Nc1ccc(-c2ccnc3[nH]nc(N)c23)cc1>>Nc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4O)cc3)c12,,ClCCl,,BrB(Br)Br,O,test
US20130190312A1,COc1cc(Cl)c(-c2csc(N)n2)c(Cl)c1.O=C(Cl)c1ccncc1>>COc1cc(Cl)c(-c2csc(NC(=O)c3ccncc3)n2)c(Cl)c1,CN(C)c1ccncc1,ClCCl,,Cl,,test
US05939439,COC(=O)c1ccc(C#N)o1>>N#Cc1ccc(CO)o1,,CCO,,[BH4-].[Na+],[Cl-].[NH4+],test
US20040019059A1,N#CC(Cl)(c1ccccc1)c1ccc(NC(=O)C2CC(c3cccnc3)=NO2)cc1>>NC(=O)C1CC(c2cccnc2)=NO1,,CO,,Cl,,test
US20090029965A1,Cc1cc(C(=O)O)ccc1OCCN1CCN(CCC(C)(C)C)CC1.Cn1ncc2c1Nc1ccccc1NC2>>Cc1cc(C(=O)N2Cc3cnn(C)c3Nc3ccccc32)ccc1OCCN1CCN(CCC(C)(C)C)CC1,CN(C)c1ccncc1,CCN(CC)CC,ClCCl,,,test
US20040058978A1,CCOC(=O)c1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1>>O=C1Nc2ccccc2/C1=C(/Nc1ccc(C(=O)O)cc1)c1ccccc1,,CCO,,[Na+].[OH-],,test
US20120142714A1,COc1ccc2nn(-c3ccc(OCc4ccccc4)cc3)cc2c1>>COc1ccc2nn(-c3ccc(O)cc3)cc2c1,[Pd],C1CCOC1,,CO,,test
US20110263598A1,COc1ccc2c(c1)[C@]1(C[C@H]1c1ccc3c(-c4ccc(N5CCOCC5)nc4)nn(COCC[Si](C)(C)C)c3c1)C(=O)N2>>COc1ccc2c(c1)[C@]1(C[C@H]1c1ccc3c(-c4ccc(N5CCOCC5)nc4)n[nH]c3c1)C(=O)N2,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130190487A1,O=C(Cl)CC[C@H]1C(=O)N(c2ccc(F)cc2)[C@@H]1c1ccc(OCc2ccc(Br)cc2)cc1.OB(O)c1ccc(F)cc1>>O=C(CC[C@H]1C(=O)N(c2ccc(F)cc2)[C@@H]1c1ccc(OCc2ccccc2)cc1)c1ccc(F)cc1,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20090239810A1,O=C(NCC(=O)N1CCC(Oc2ccccc2[N+](=O)[O-])CC1)c1cc(-c2ccccc2)[nH]n1>>Nc1ccccc1OC1CCN(C(=O)CNC(=O)c2cc(-c3ccccc3)[nH]n2)CC1,[Pd],C1CCOC1,CO,,,test
US20070191448A1,COc1ccccc1C#N.Cc1ccc(N)cc1>>COc1ccccc1C(=N)Nc1ccc(C)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US05304644,O=[N+]([O-])c1ccccc1F.Oc1ccccc1Cl>>O=[N+]([O-])c1ccccc1Oc1ccccc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20110269751A1,O=CCCC=O.O=[N+]([O-])C=C1NCCN1Cc1ccc(Cl)nc1>>O=[N+]([O-])C1=C2N(Cc3ccc(Cl)nc3)CCN2C2CCC1O2,,CC#N,,Cl,,test
US20030191124A1,CN1CCC(=O)CC1.O=S(=O)(Nc1ccc2[nH]ccc2c1)c1cccc2ccccc12>>CN1CC=C(c2c[nH]c3ccc(NS(=O)(=O)c4cccc5ccccc45)cc23)CC1,,CO,,C[O-].[Na+],,test
US20160016981A1,CCCCCCCCCCCCCCNC.O=S1(=O)CCCO1>>CCCCCCCCCCCCCC[NH+](C)CCCS(=O)(=O)[O-],,CCOC(C)=O,,,,test
US20030060466A1,C1=C(c2ccccc2)CCNC1.N#Cc1c(Cl)nc(NCCO)nc1NCCO>>N#Cc1c(NCCO)nc(NCCO)nc1N1CC=C(c2ccccc2)CC1,,CCO,,CCN(C(C)C)C(C)C,Cl,test
US20040167160A1,CCCOc1c(Br)cc(C(C)(C)C)cc1C(C)(C)C.COB(OC)OC>>CCCOc1c(B(O)O)cc(C(C)(C)C)cc1C(C)(C)C,,COCCOC,,[Li]C(C)(C)C,,test
US20150119362A1,CCOC(=O)CC(=O)CC.N=C(N)c1cccc(Cl)c1>>CCc1cc(=O)[nH]c(-c2cccc(Cl)c2)n1,,CCO,,C[O-].[Na+],,test
US20100324053A1,CSC(=Nc1ccc(F)c(C(F)(F)F)c1)NC(=O)C[C@H](C)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C.Cc1cc(NN)ccn1>>Cc1cc(-n2nc(Nc3ccc(F)c(C(F)(F)F)c3)nc2C[C@H](C)O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)ccn1,Cl[Hg]Cl,CN(C)C=O,,,,test
US20090005353A1,CC(C)(C)N1C(=O)C(Cl)=C(c2ccccc2)S1(=O)=O.NC1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1>>CC(C)(C)N1C(=O)C(NC2CCN(c3ncc(C(F)(F)F)cc3Cl)CC2)=C(c2ccccc2)S1(=O)=O,,CCOC(C)=O,CN(C)C=O,,,test
US20070225335A1,CCOC(=O)c1cnn(-c2cccc(F)c2)c1-c1ccncc1>>O=C(O)c1cnn(-c2cccc(F)c2)c1-c1ccncc1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20080287458A1,CCN.COC(=O)c1c(Cc2ccc(C(=O)O)nc2)c(=O)c2ccc(C)nc2n1-c1ccccc1>>CCNC(=O)c1ccc(Cc2c(C(=O)OC)n(-c3ccccc3)c3nc(C)ccc3c2=O)cn1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20040229861A1,COC(=O)c1nccnc1Br.NC1CCN(Cc2ccccc2)CC1>>COC(=O)c1nccnc1NC1CCN(Cc2ccccc2)CC1,,CC(C)O,CCOC(C)=O,CO,,test
US20080280917A1,Cc1csc(-c2ccc(=O)n(CCN(C)C(=O)OC(C)(C)C)n2)c1>>CNCCn1nc(-c2cc(C)cs2)ccc1=O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20140051672A1,COc1ccc(C(=O)O)cc1Br.Cn1cc(CN)cn1>>COc1ccc(C(=O)NCc2cnn(C)c2)cc1Br,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20070265303A1,CC(C)N(CC[C@H](c1ccccc1)c1cc(CCOc2cccc(CCNC(=O)OC(C)(C)C)c2)ccc1OCc1ccccc1)C(C)C>>CC(C)N(CC[C@H](c1ccccc1)c1cc(CCOc2cccc(CCN)c2)ccc1OCc1ccccc1)C(C)C,,ClCCl,,Cl,,test
US05580866,COS(=O)(=O)OC.ON=C1CSc2ccccc2CN1>>CON=C1CSc2ccccc2CN1,,CCO,,[Na+].[OH-],,test
US05182283,CCOC(C)=O.CN1CCCC(O)(c2nccnc2Cl)C1.O=C(O)C(=O)O>>COc1nccnc1C1=CCCN(C)C1.O=C(O)C(=O)O,,CCOC(C)=O,,O=S(Cl)Cl,,test
US20090093454A1,ClCc1nccn1Cc1ccccc1.c1cnc2c(c1)CC[C@H]1CCCN(Cc3nc4ccccc4[nH]3)[C@H]21>>c1ccc(Cn2ccnc2Cn2c(CN3CCC[C@@H]4CCc5cccnc5[C@H]43)nc3ccccc32)cc1,,CN(C)C=O,O,Cl,[I-].[K+],test
US20040152704A1,C[C@@H]1CCCN1CCc1cc2ccc(-c3cccn3C(=O)OC(C)(C)C)cc2nn1>>C[C@@H]1CCCN1CCc1cc2ccc(-c3ccc[nH]3)cc2nn1,,C1CCOC1,,C[O-].[Na+],,test
US20040229900A1,CCS(=O)(=O)CCCOS(=O)(=O)c1ccc(C)cc1.N#Cc1ccc(NC(=O)N2CC3CNCC(C3)C2)cc1>>CCS(=O)(=O)CCCN1CC2CC(C1)CN(C(=O)Nc1ccc(C#N)cc1)C2,,CC#N,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20130040931A1,Cc1cccc(C(=O)N2CCCC2)c1-c1ccc2nc(N)c(C3=CCOCC3)cc2c1>>Cc1cccc(C(=O)N2CCCC2)c1-c1ccc2nc(N)c(C3CCOCC3)cc2c1,[Pd],CCO,,N#N,,test
US20040157886A1,N#Cc1cccc(N)c1.O=C(Cl)CCl>>N#Cc1cccc(NC(=O)CCl)c1,,O,,,,test
US04734430,CNN.Cn1ncc2c1CCCC(=CO)C2=O>>Cn1ncc2c1CCCc1cnn(C)c1-2,,CO,,,,test
US06008245,CC1(C)Oc2ccc(OCCCC(F)(F)F)cc2[C@H]2O[C@H]21.CNS(C)(=O)=O>>CNS(=O)(=O)C[C@H]1c2cc(OCCCC(F)(F)F)ccc2OC(C)(C)[C@@H]1O,,CS(C)=O,,O,[H-].[Na+],test
US20160222033A1,C=Cc1cc(F)c(F)cc1OCc1ccccc1>>CCc1cc(F)c(F)cc1O,[Pd],CO,,,,test
US20150094296A1,CC[C@]1(C#N)CCN(c2ccnc(Nc3cnn(C(C)(C)C(=O)OC(C)(C)C)c3)n2)C1=O.Cl>>CC[C@]1(C#N)CCN(c2ccnc(Nc3cnn(C(C)(C)C(=O)O)c3)n2)C1=O.Cl,,CCOC(C)=O,,,,test
US04303660,Nc1ccccc1-c1[nH]ncc1[N+](=O)[O-].O=C(Cl)c1ccccc1>>O=[N+]([O-])c1cnn2c(-c3ccccc3)nc3ccccc3c12,,c1ccncc1,,O,,test
US05556909,CC(C)C1NS(=O)(=O)N(CSc2ccccc2)C1=O.O=S(=O)(Cl)Cl>>CC(C)C1NS(=O)(=O)N(CCl)C1=O,,ClCCl,,,,test
US20080193795A1,CCOC=C(C#N)C#N.Cc1ccc(Nc2nccc(-c3ccc(C)cc3)c2N)cc1>>Cc1ccc(-c2ccnc3c2ncn3-c2ccc(C)cc2)cc1,,CC(C)O,,,,test
US20030105078A1,CCOC(=O)COc1cc(C)c(Cc2ccc(OCc3ccccc3)c(S(=O)(=O)c3ccc(F)cc3)c2)c(C)c1>>CCOC(=O)COc1cc(C)c(Cc2ccc(O)c(S(=O)(=O)c3ccc(F)cc3)c2)c(C)c1,[Pd],CCO,,,,test
US20150336938A1,COc1cc2c(OC(=O)OC(C)(C)C)c3c(c(-c4ccsc4)c2cc1OC)C(=O)OC3>>COc1cc2c(O)c3c(c(-c4ccsc4)c2cc1OC)C(=O)OC3,,ClCCl,,C1CCNCC1,Cl,test
US20060069140A1,COC(=O)c1ccc(C(=O)NNC(C)=C2C(=O)N(c3ccc(C(C)(C)C)cc3)N=C2C)cc1>>CC1=NN(c2ccc(C(C)(C)C)cc2)C(=O)C1=C(C)NNC(=O)c1ccc(C(=O)O)cc1,,CO,,Cl,[Na+].[OH-],test
US07439242B2,CCOC(=O)c1cc(N)ccc1Oc1cncc(Cl)c1.COc1ccc(Br)cc1S(=O)(=O)Cl>>CCOC(=O)c1cc(NS(=O)(=O)c2cc(Br)ccc2OC)ccc1Oc1cncc(Cl)c1,,ClCCl,,,,test
US20080033013A1,COc1ccc(-n2ncc(C=O)c2C)cc1.OCCO>>COc1ccc(-n2ncc(C3OCCO3)c2C)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080318953A1,C1COCCN1.Clc1cc(Cl)nc(Cl)c1>>Clc1cc(Cl)nc(N2CCOCC2)c1,,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20080100902A1,OCCI.c1ccc2[nH]cnc2c1>>OCCn1cnc2ccccc21,,CCOC(C)=O,CO,C1CCOC1,[H-].[Na+],test
US20120214766A1,CC(C)(C)[C@H](N)CO.O=Cc1ccccc1>>CC(C)(C)[C@@H](CO)NCc1ccccc1,,c1ccccc1,,[BH4-].[Na+],,test
US20130018043A1,CCN(C(C)C)C(C)C.Cc1c(N)c(=O)c2ccc(Cl)cc2n1-c1ccccc1Cl.O=C(O)c1ccc(N2CCOCC2)nc1>>O=C(NCc1cn(-c2ccccc2Cl)c2cc(Cl)ccc2c1=O)c1ccc(N2CCOCC2)cc1,,CCOC(C)=O,,ClCCl,,test
US20080108814A1,C[C@H](N)CO.O=Cc1ccc(Cl)cc1>>C[C@@H](CO)NCc1ccc(Cl)cc1,,CCO,CO,[BH4-].[Na+],,test
US20150238601A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cnc(Cl)nc1Nc1ccc2[nH]ncc2c1>>COc1cnc(Cl)nc1N(C(=O)OC(C)(C)C)c1ccc2c(cnn2C(=O)OC(C)(C)C)c1,CN(C)c1ccncc1,ClCCl,,,,test
US20090018163A1,CC(OCC1(c2ccc(F)cc2)CCN(C(=O)OC(C)(C)C)CC1)c1cc(Br)cc2cccnc12.OB(O)C1CC1>>CC(OCC1(c2ccc(F)cc2)CCN(C(=O)OC(C)(C)C)CC1)c1cc(C2CC2)cc2cccnc12,,Cc1ccccc1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150005284A1,N#Cc1cc(Br)ccc1F.OC1CCOCC1>>N#Cc1cc(Br)ccc1OC1CCOCC1,,CN(C)C=O,,[H-].[Na+],,test
US20050085541A1,CCOC(=O)CC(=O)Nc1cc(C)c(Oc2ccc(O)c(CC3CCOCC3)c2)c2c1CCC2>>Cc1cc(NC(=O)CC(=O)O)c2c(c1Oc1ccc(O)c(CC3CCOCC3)c1)CCC2,,CO,,[Na+].[OH-],,test
US20080207704A1,Cc1c(C(=O)NCC(=O)C2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1>>Cc1c(-c2ncc(C3CCCCC3)o2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1,,C1CCOC1,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US20040077557A1,COC(CBr)OC.c1csc(-c2c[nH]cn2)c1>>COC(Cn1cnc(-c2cccs2)c1)OC,,CN(C)C=O,,[H-].[Na+],,test
US05352684,CC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(=O)CCCCCCl.NC1=CC(=O)CCC1>>CC1=C(C(=O)CCCCCCl)C(c2cccc([N+](=O)[O-])c2)C2=C(CCCC2=O)N1,,CO,,,,test
US20080085890A1,CN(C)CC1CCCN1c1ccc([N+](=O)[O-])cc1F>>CN(C)CC1CCCN1c1ccc(N)cc1F,[Pd],CO,,,,test
US05405851,CCCCCCCCCCCCO.O=C(O)CCC(=O)c1ccc([N+](=O)[O-])cc1>>CCCCCCCCCCCCOC(=O)CCC(=O)c1ccc([N+](=O)[O-])cc1,,C1CCOC1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20160200695A1,C#CCOc1ccc2nc(N)sc2c1.O=C(O)c1ccc(C(=O)c2ccccc2)cc1>>C#CCOc1ccc2nc(NC(=O)c3ccc(C(=O)c4ccccc4)cc3)sc2c1,CN(C)c1ccncc1,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20090275537A1,CN(C(=O)NCc1cccc(F)c1F)[C@@H](CCCOP(=O)(OC(C)(C)C)OC(C)(C)C)CO[Si](C)(C)C(C)(C)C>>CN(C(=O)NCc1cccc(F)c1F)[C@H](CO)CCCOP(=O)(OC(C)(C)C)OC(C)(C)C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140200206A1,CC(C)(Cn1ncc([N+](=O)[O-])c1Cl)O[Si](C)(C)C>>CC(C)(O)Cn1ncc(N)c1Cl,[Fe],CCO,,[Cl-].[NH4+],,test
US05599832,COc1ccc2[nH]c(C(F)(F)F)cc2c1.O=C=NS(=O)(=O)Cl>>COc1ccc2[nH]c(C(F)(F)F)c(C#N)c2c1,,CC#N,,CN(C)C=O,O,test
US20160115128A1,COC(=O)C1CCN(c2cc(OC)ccc2C(=O)N(CC(C)(C)C)c2ccccn2)CC1C>>COc1ccc(C(=O)N(CC(C)(C)C)c2ccccn2)c(N2CCC(CO)C(C)C2)c1,,C1CCOC1,,Cl,[BH4-].[Li+],test
US20130237525A1,BrC(Br)(Br)Br.OCc1ccc(OCCF)cc1>>FCCOc1ccc(CBr)cc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20080160028A1,Cc1nc(-c2ccc(OC(C)C)cc2)nc2sc(C(N)=O)c(N)c12.O=C(Cl)OC(Cl)(Cl)Cl>>Cc1nc(-c2ccc(OC(C)C)cc2)nc2sc3c(=O)[nH]c(=O)[nH]c3c12,,C1COCCO1,,O,,test
US20040122063A1,BrCc1ncsc1CBr.CC(C)(C)N>>CC(C)(C)N1Cc2ncsc2C1,,C1COCCO1,,,,test
US20130165472A1,CC(=O)Nc1cc(-c2cn(COCC[Si](C)(C)C)c(-c3ccccc3Cl)n2)ccn1>>CC(=O)Nc1cc(-c2c[nH]c(-c3ccccc3Cl)n2)ccn1,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120238582A1,CCO.O=C1Nc2ccc(C3(C(=O)O)CC3)cc2C1=O>>CCOC(=O)C1(c2ccc3c(c2)C(=O)C(=O)N3)CC1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20150018363A1,Cc1c(CO)nc2ccc(-n3ccc(OCc4ccc(F)cc4)cc3=O)cn12.O=S(Cl)Cl>>Cc1c(CCl)nc2ccc(-n3ccc(OCc4ccc(F)cc4)cc3=O)cn12,,ClCCl,,,,test
US20150087626A1,CCN(CC)S(F)(F)F.COC(=O)c1ccc([C@H](C)NC(=O)[C@H]2CC(O)CCN2C(=O)OC(C)(C)C)cc1>>COC(=O)c1ccc([C@H](C)NC(=O)[C@H]2CC(F)CCN2C(=O)OC(C)(C)C)cc1,,ClCCl,,,,test
US20060194969A1,COC(=O)c1cc(OCc2c(C)cccc2C)c2nc(C)n(C)c2c1>>Cc1cccc(C)c1COc1cc(C(=O)O)cc2c1nc(C)n2C,,C1COCCO1,,Cl,[Na+].[OH-],test
US20030225059A1,NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=CC1(c2ccccc2)CCC2(CC1)OCCO2>>FC(F)(F)c1cc(CNCC2(c3ccccc3)CCC3(CC2)OCCO3)cc(C(F)(F)F)c1,,CC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20080287510A1,CCCCn1c2c(s/c1=N\C(=O)c1cc(Cl)ccc1OC)C(=O)COC2.[Li]C>>CCCCn1c2c(s/c1=N\C(=O)c1cc(Cl)ccc1OC)C(C)(O)COC2,,C1CCOC1,,,,test
US20090042925A1,CC(C)C(=O)OC(=O)C(C)C.NCCCn1c(CCl)nc2cnc3cccnc3c21>>CC(C)C(=O)NCCCn1c(CCl)nc2cnc3cccnc3c21,,ClCCl,,CCN(CC)CC,Cl,test
US20110015200A1,COC(=O)C1CCC(=O)N1.N#CCBr>>COC(=O)C1CCC(=O)N1CC#N,,CC#N,,[H-].[Na+],,test
US20030158198A1,Nc1cccc2cnc(Cl)cc12.O=C(Cl)Cl>>O=C=Nc1cccc2cnc(Cl)cc12,,CCN(CC)CC,Cc1ccccc1,,,test
US20050107381A1,CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1ccc(C=CC(=O)OC)cn1>>CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1ccc(CCC(=O)OC)cn1,O=[Pt]=O,CCOC(C)=O,,,,test
US20040204586A1,CCOC(=O)c1c(O)c2ccccc2n(Cc2ccc(F)cc2)c1=O.NC1CCCCC1>>O=C(NC1CCCCC1)c1c(O)c2ccccc2n(Cc2ccc(F)cc2)c1=O,,Cc1ccccc1,O,,,test
US20020193398A1,Cc1ccccc1-c1csnn1.O=C1CCC(=O)N1Br>>BrCc1ccccc1-c1csnn1,,ClC(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20140315917A1,Cn1cc(-c2cc(Oc3ccc(N)nc3)ccn2)cn1.N#CCN1CCNC1=O.O=C(Cl)Cl>>Cn1cc(-c2cc(Oc3ccc(NC(=O)N4CCN(CC#N)C4=O)nc3)ccn2)cn1,,ClCCl,,c1ccncc1,,test
US20090069340A1,CC(C)(C)OC(=O)N1CCC(CC=Cc2cccnc2)CC1>>CC(C)(C)OC(=O)N1CCC(CCCc2cccnc2)CC1,[Pt],CO,,[H][H],,test
US20140329797A1,CS(=O)(=O)OCc1ccnc(Cl)c1.O=c1ccc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)c[nH]1>>O=c1ccc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)cn1Cc1ccnc(Cl)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20080194617A1,Cc1nn(C)c(Cl)c1C=O.Clc1n[nH]c2ccccc12>>Cc1nn(C)c(-n2nc(Cl)c3ccccc32)c1C=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05332739,O=c1cc(Cl)[nH]c(=O)[nH]1.c1ccc(OCCCN2CCNCC2)cc1>>O=c1cc(N2CCN(CCCOc3ccccc3)CC2)[nH]c(=O)[nH]1,,C1COCCO1,,CCN(CC)CC,,test
US20100048613A1,CN1C2CCCC1CC(NC(=O)c1nn(C)c3ccccc13)C2.Cl>>CN1C2CCCC1CC(NC(=O)c1nn(C)c3ccccc13)C2.Cl,,Cc1ccccc1,,,,test
US20060211868A1,C=C(CC(=O)O)C(=O)O.Nc1ccc(OCc2cccc(F)c2)cc1>>O=C(O)C1CC(=O)N(c2ccc(OCc3cccc(F)c3)cc2)C1,,CC(=O)O,Cc1ccccc1,,,test
US20160200725A1,C=CC(=O)Cl.CNc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)c(=O)n(CCN(C)C3CNC3)c2n1>>C=CC(=O)N1CC(N(C)CCn2c(=O)c(-c3c(Cl)c(OC)cc(OC)c3Cl)cc3cnc(NC)nc32)C1,,ClCCl,,CO,,test
US20100069383A1,CNCc1ccccc1OC.Clc1nc(Cl)c2ccccc2n1>>COc1ccccc1CN(C)c1nc(Cl)nc2ccccc12,Cl,CC(C)O,,O=C([O-])O.[Na+],,test
US05319100,CC(=O)OC(C)=O.CC(C)(C)c1cc(C=C2CCN(C(=O)NO)C2=O)cc(C(C)(C)C)c1O>>CC(=O)ONC(=O)N1CCC(=Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C1=O,,c1ccncc1,,,,test
US20160251456A1,COC(Cl)Cl.Cc1cc(C)c(CCl)c(C)c1.O>>Cc1cc(C)c(CCl)c(C)c1C=O,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US04689327,CS(=O)(=O)N=C=O.Fc1cccc(N2CCN(CCOc3ccccc3C3NCCS3)CC2)c1>>CS(=O)(=O)NC(=O)N1CCSC1c1ccccc1OCCN1CCN(c2cccc(F)c2)CC1,,CC(C)=O,,,,test
US20050187298A1,C=Cc1cc(OC)cc2c1C(=O)CCC2(C)C>>CCc1cc(OC)cc2c1C(=O)CCC2(C)C,[Pd],CCOC(C)=O,,,,test
US05441950,CCN(CC)CC.Nc1cc(Cl)ccc1Sc1ccccc1.O=C(Cl)Cl>>O=C(Cl)N1Cc2ccccc2Sc2ccc(Cl)cc21,,C1CCOC1,,,,test
US20130065894A1,CCOC(=O)CC(=O)C(=O)OCC.Nc1cc[nH]n1>>CCOC(=O)c1cc(O)nc2[nH]ncc12,,O,,CC(=O)O,[Na],test
US20030114469A1,CC(=O)N1C=Cc2cc(Cl)ccc2C1.Cl.O=CC(=O)O>>Cl.O=C(O)Cc1cncc2ccc(Cl)cc12,,Cl,,,,test
US20110166147A1,Clc1nccn2c(Br)cnc12.NCc1ccc(S(N)(=O)=O)cc1>>NS(=O)(=O)c1ccc(CNc2nccn3c(Br)cnc23)cc1,,CC(C)CO,,CCN(C(C)C)C(C)C,Cl,test
US20160145247A1,BrC(Br)(Br)Br.CC(C)(C)[Si](C)(C)OCc1cc(Br)cc(CO)c1>>CC(C)(C)[Si](C)(C)OCc1cc(Br)cc(CBr)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20080096860A1,CC(C)(C)N.COC(=O)c1ccc(S(=O)(=O)Cl)o1>>COC(=O)c1ccc(S(=O)(=O)NC(C)(C)C)o1,,ClCCl,,,,test
US20030220324A1,CC(C)(C)OC(=O)N1CCNCC1.CS(=O)(=O)N(CC1CC1)c1ccccc1N1CCN(C(=O)[C@H](CC(=O)O)Cc2ccc(Cl)cc2)CC1>>CC(C)(C)OC(=O)N1CCN(C(=O)C[C@H](Cc2ccc(Cl)cc2)C(=O)N2CCN(c3ccccc3N(CC3CC3)S(C)(=O)=O)CC2)CC1,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20150297586A1,COc1ccccc1N1CCNCC1.ClCCCCn1cnc2ccccc21>>COc1ccccc1N1CCN(CCCCn2cnc3ccccc32)CC1,,CC#N,,CCN(C(C)C)C(C)C,[I-].[K+],test
US20080227772A1,Nc1ccc(-c2ccc(C(=O)N3CCN4CCC3CC4)o2)cc1.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)Nc1ccc(-c2ccc(C(=O)N3CCN4CCC3CC4)o2)cc1,,ClCCl,,[Na+].[OH-],,test
US05968952,CCCI.Cn1c(=O)cc(-c2cccc(O)c2)c2cc(C(=O)c3ccc(Cl)cc3)ccc21>>CCCOc1cccc(-c2cc(=O)n(C)c3ccc(C(=O)c4ccc(Cl)cc4)cc23)c1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20100261771A1,CC(C)(C)OC(=O)NC(CN)c1cccc(Cl)c1Cl.N#C[O-]>>CC(C)(C)OC(=O)NC(CNC(N)=O)c1cccc(Cl)c1Cl,,CO,O,Cl,,test
US04824958,COC(=O)C(=O)OC.COC(=O)C(O)SC(C)(O)C(=O)OC>>COC(=O)c1sc(C)c(O)c1O,,CO,,[Na],,test
US20130090340A1,CC(C)(C)OC(=O)N1CCn2c(Br)c(-c3cccc(F)c3)c(C(=O)n3ccnc3)c2C1>>CC(C)(C)OC(=O)N1CCn2c(Br)c(-c3cccc(F)c3)c(C(N)=O)c2C1,,O,,N,,test
US20150361067A1,CC(=O)c1ccc(S(=O)(=O)N=[N+]=[N-])c(N)c1.COC(=O)Cc1cc(Cl)c2c(c1Cl)C(=O)N(Cc1c(C)cc(C)nc1OCc1ccccc1)CC2>>COC(=O)C(=[N+]=[N-])c1cc(Cl)c2c(c1Cl)C(=O)N(Cc1c(C)cc(C)nc1OCc1ccccc1)CC2,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20100249399A1,CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(CC2CCNCC2)CCO1.C[Si](C)(C)N=C=O>>CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(CC2CCN(C(N)=O)CC2)CCO1,,ClCCl,,,,test
US20160039745A1,CI.Fc1n[nH]c2cc(Br)ccc12>>Cn1nc(F)c2ccc(Br)cc21,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110130396A1,COc1ccc(B(O)O)cc1OC.Ic1cnc2sc(NCc3ccccc3)nn12>>COc1ccc(-c2cnc3sc(NCc4ccccc4)nn23)cc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,[Na+].[OH-],,test
US20150038528A1,CCC(C#N)C(=O)OC>>CCC(CN)C(=O)OC,[Ni],CCO,,,,test
US20120270857A1,Cl.O=C1c2cccc3ccn(c23)CCCN1[C@H]1CN2CCC1CC2>>Cl.O=C1c2cccc3ccn(c23)CCCN1[C@H]1CN2CCC1CC2,,CO,,,,test
US20160214978A1,Cc1nn2ccccc2c1C(=O)O.O=C1CCC(=O)N1I>>Cc1nn2ccccc2c1I,,CO,ClC(Cl)Cl,,,test
US20100273770A1,CC(C)Oc1ncc(C(=O)O)cc1Cl.CCOC(=O)CCCC1c2cccc(C(=N)NO)c2OCCN1C(=O)OC(C)(C)C>>CCOC(=O)CCCC1c2cccc(-c3noc(-c4cnc(OC(C)C)c(Cl)c4)n3)c2OCCN1C(=O)OC(C)(C)C,CN(C)C=O,CC#N,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20100240926A1,NCc1ccccc1.O=C(N[C@H](CO)C(=O)O)OCc1ccccc1>>O=C(N[C@H](CO)C(=O)NCc1ccccc1)OCc1ccccc1,,CCOC(C)=O,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US04883815,C=C(C)C.CC(=O)NCCCC(=O)c1ccc(Cl)cc1CCC(=O)O>>CC(=O)NCCCC(=O)c1ccc(Cl)cc1CCC(=O)OC(C)(C)C,,C1CCOC1,,O=S(=O)(O)O,,test
US05710139,Cc1cc2ccccc2nc1C.O=C1CCC(=O)N1Br>>Cc1nc2ccccc2cc1CBr,,ClC(Cl)(Cl)Cl,,,,test
US04840662,Cc1nc(Cl)c(N)c(Cl)n1.O=[N+]([O-])c1cc(C(F)(F)F)c(Cl)c([N+](=O)[O-])c1Cl>>CC1N=C(Cl)C(N)=C(Cl)N1c1c([N+](=O)[O-])cc(C(F)(F)F)c(Cl)c1[N+](=O)[O-],,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20140031360A1,COc1ccc(COc2cc(-c3nn(C4CCCCO4)c4ccc(Nc5c(F)cccc5F)cc34)nc(N(C)C)n2)cc1>>CN(C)c1nc(-c2n[nH]c3ccc(Nc4c(F)cccc4F)cc23)cc(=O)[nH]1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100144694A1,CC1(C)C(=O)N(C2C3CC4CC(C3)CC2C4)N1C(=O)CO.Fc1ccc(Br)cn1>>CC1(C)C(=O)N(C2C3CC4CC(C3)CC2C4)N1C(=O)COc1ccc(Br)cn1,,CN(C)C=O,,O,[Na+].[OH-],test
US06004967,COC(=O)c1cc(OC)c(OC)cc1N.COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC.NC=O>>COc1cc2cnc(=O)[nH]c2cc1OC,,O,,,,test
US04302398,COC(=O)C1(O)Cc2c(OC)ccc(OC)c2C2(C1)SCCS2>>COc1ccc(OC)c2c1CC(O)(CO)CC21SCCS1,,C1CCOC1,,[BH4-].[Na+],,test
US20100069368A1,COC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)CCN1.COC(=O)c1cnc(Cl)nc1C(F)(F)F>>COC(=O)c1cnc(N2CCN(C(=O)OC(C)(C)C)C[C@H]2C(=O)OC)nc1C(F)(F)F,,C1COCCO1,,CCN(CC)CC,,test
US20050164402A1,C=CCCCCCCCCCBr.OCCOCCOCCOCCOCCOCCO>>C=CCCCCCCCCCOCCOCCOCCOCCOCCOCCO,,CCOC(C)=O,CO,[Na+].[OH-],,test
US20160194358A1,C[C@@H](CO)NC(=O)OCc1ccccc1>>C[C@@H](C=O)NC(=O)OCc1ccccc1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20150240037A1,C=CC(=O)NCCOC(=O)c1cncc(C(=O)OCCNC(=O)C=C)c1.CI>>C=CC(=O)NCCOC(=O)c1cc(C(=O)OCCNC(=O)C=C)c[n+](C)c1.[I-],,CN(C)C=O,,,,test
US20070004772A1,Cc1cc(-c2ccc(Cl)cc2)c(Br)c2n[nH]c(=O)n12.N#Cc1ccc(CCl)nc1>>Cc1cc(-c2ccc(Cl)cc2)c(Br)c2nn(Cc3ccc(C#N)cn3)c(=O)n12,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US04927822,CCCC(N[C@@H](C)C(=O)OCc1ccccc1)C(=O)OCC>>CCC[C@H](N[C@@H](C)C(=O)O)C(=O)OCC,[Pd],CCO,,,,test
US20090181966A1,CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(OCCCNC(=O)NCCCl)cc2)c2ccccc21>>CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(OCCCN3CCNC3=O)cc2)c2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100179137A1,CC(C)(C)[Si](C)(C)OCCS(N)(=O)=O.CCOc1cccc(OCc2c(Cl)cc(Cl)c(=O)n2CCc2ccc(C(=O)n3ccnc3)cc2)c1>>CCc1cccc(OCc2c(Cl)cc(Cl)c(=O)n2CCc2ccc(C(=O)NS(=O)(=O)CCO)cc2)c1,,C1COCCO1,ClC(Cl)Cl,C1CCC2=NCCCN2CC1,O,test
US20060041144A1,COc1ccc(-c2cnccc2NC(=O)C(C)(C)C)cc1OC>>COc1ccc(-c2cnccc2N)cc1OC,,O,,CO,[K+].[OH-],test
US20060235231A1,NO.O=C(O)C=CC=CCS(=O)(=O)c1ccccc1>>O=C(C=CC=CCS(=O)(=O)c1ccccc1)NO,,C1CCOC1,ClCCl,O=C(Cl)C(=O)Cl,,test
US20120165345A1,CC1(C)OB(c2cnn(-c3cccnc3)c2)OC1(C)C.Nc1cccc(Br)n1>>Nc1cccc(-c2cnn(-c3cccnc3)c2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20100324041A1,CC(C)(C)OC(=O)NCCC(=O)N1CCN(c2c(Br)cnc3[nH]cc(NC(=O)c4cccnc4)c23)CC1>>NCCC(=O)N1CCN(c2c(Br)cnc3[nH]cc(NC(=O)c4cccnc4)c23)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050004143A1,Cc1nn(C)c(NC(=O)c2ccccc2F)c1C#N.OO>>Cc1nn(C)c2nc(-c3ccccc3F)[nH]c(=O)c12,,[Na+],[OH-],Cl,,test
US20080004273A1,O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.O=C1NCCN1c1cccc(F)c1>>O=C(Cl)N1CCN(c2cccc(F)c2)C1=O,,C1CCOC1,,,,test
US20020016463A1,COc1ccccc1O.ClCC1CO1>>COc1ccc(OCC2CO2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06248740B1,CCOC(=O)C(C)(C)c1cn2nc(NCCCN3CCC(NC(c4ccccc4)c4ccccc4)CC3)ccc2n1>>CC(C)(C(=O)O)c1cn2nc(NCCCN3CCC(NC(c4ccccc4)c4ccccc4)CC3)ccc2n1,,CCO,,[Na+].[OH-],,test
US20140194415A1,N#CC(Br)c1ccc(-c2ccc3cccnc3c2)cc1.O=C1COC2(CCNCC2)CN1C1CC1>>N#CC(c1ccc(-c2ccc3cccnc3c2)cc1)N1CCC2(CC1)CN(C1CC1)C(=O)CO2,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20130259830A1,CCOC(=O)CBr.Cc1[nH]c2c(c1Cc1cccnc1S(=O)(=O)c1ccc(F)cc1)C(=O)CC(C)(C)C2>>CCOC(=O)Cn1c(C)c(Cc2cccnc2S(=O)(=O)c2ccc(F)cc2)c2c1CC(C)(C)CC2=O,,CC#N,O,[I-].[K+],,test
US20160060267A1,CC(C)c1c(-c2cnn(C(C)(C)C(=O)OC(C)(C)C)c2)[nH]c2c(C#N)cnn2c1=O>>CC(C)c1c(-c2cnn(C(C)(C)C(=O)O)c2)[nH]c2c(C#N)cnn2c1=O,,C1COCCO1,Cl,,,test
US20100160303A1,CS(=O)(=O)Cl.Cc1c(-c2ccc(C(N)=O)c3[nH]c4cc(CN)ccc4c23)cccc1N1Cc2ccccc2C1=O>>Cc1c(-c2ccc(C(N)=O)c3[nH]c4cc(CNS(C)(=O)=O)ccc4c23)cccc1N1Cc2ccccc2C1=O,,C1CCOC1,,,,test
US20030092694A1,CC(=O)OC(C)=O.Nc1ccc2c(c1)OC(CO)CO2>>CC(=O)Nc1ccc2c(c1)OC(CO)CO2,,ClCCl,,CCN(CC)CC,,test
US20090069344A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1CCN(c2ccc(C(=O)Nc3ccc(O)cc3)cc2)CC1>>C=C(Nc1ccc(OC(C)=O)cc1)c1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)cc1,,ClCCl,,CCN(CC)CC,,test
US20120289474A1,CCc1nc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(-c4ccccc4)cc32)co1.Cl>>CCc1nc(Cn2c(=O)n(C3CCNCC3)c(=O)c3sc(-c4ccccc4)cc32)co1.Cl,,C1COCCO1,,,,test
US05166367,CCNCC1COc2ccc(O)cc2O1.O=c1ccc2ccc(OCCCCl)cc2o1>>CCN(CCCOc1ccc2ccc(=O)oc2c1)CC1COc2ccc(O)cc2O1,,CN(C)C=O,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US04352748,O=C1CCc2ccccc21>>OC1CCc2ccccc21,,CCOCC,c1ccccc1,,,test
US20070032470A1,COc1cccc(CN(C[C@@H](O)[C@H](Cc2cc(F)cc(F)c2)NC(=O)c2cc(C(C)=O)cc(N3CCCCS3(=O)=O)c2)C(=O)OC(C)(C)C)c1>>COc1cccc(CN(C[C@@H](O)[C@H](Cc2cc(F)cc(F)c2)NC(=O)c2cc(C(C)O)cc(N3CCCCS3(=O)=O)c2)C(=O)OC(C)(C)C)c1,,CO,,[BH4-].[Na+],,test
US20150057238A1,CI.O=c1[nH]c2c(Cl)cc(Br)cc2o1>>Cn1c(=O)oc2cc(Br)cc(Cl)c21,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20140113877A1,BrCc1ccccc1.CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3cc(-c4ccccc4)sc3c2=O)CC1>>CC(C)(C)OC(=O)N1CCC(n2c(=O)c3sc(-c4ccccc4)cc3n(Cc3ccccc3)c2=O)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150005279A1,CC(C)(C)OC(=O)N1CCC[C@@H](N)C1.O=C(O)c1nccs1>>CC(C)(C)OC(=O)N1CCC[C@@H](NC(=O)c2nccs2)C1,,ClCCl,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150353489A1,CC(C)(C)OC(=O)OC(C)(C)C.NCCCCCCO>>CC(C)(C)OC(=O)NCCCCCCO,,CO,,,,test
US20140140956A1,BrP(Br)Br.COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCO)c(-c4cccc(S(C)(=O)=O)c4)n3)nc2c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCBr)c(-c4cccc(S(C)(=O)=O)c4)n3)nc2c1,,CN(C)C=O,,,,test
US20100130495A1,CC(C(=O)C1CN(C(=O)OC(C)(C)C)CCC1=O)c1ccccc1.Cc1nccn1-c1ccc(NC(=N)N)cc1>>Cc1nccn1-c1ccc(Nc2nc3c(c(C(C)c4ccccc4)n2)CN(C(=O)OC(C)(C)C)CC3)cc1,,CCO,,C,C[O-].[Na+],test
US20120142717A1,COc1cc(Cc2c[nH]c(=S)[nH]c2=O)ccn1>>O=c1cc(Cc2c[nH]c(=S)[nH]c2=O)cc[nH]1,,CC(=O)O,,Cl,,test
US04656259,CCCCNC(N)=O.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.O=[N+]([O-])Nc1ccccc1>>CCCCN(N=O)C(=O)N[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O,,CO,,Cl,,test
US20090176837A1,CCCCCCNC(=O)CCl.CCOC(=O)c1ccc(-c2ccc(O)cc2)cc1>>CCCCCCNC(=O)COc1ccc(-c2ccc(C(=O)O)cc2)cc1,,CC#N,,[I-].[K+],,test
US20140275111A1,CN(C)C(=O)c1ccc([N+](=O)[O-])cc1C(F)(F)F>>CN(C)C(=O)c1ccc(N)cc1C(F)(F)F,[Pd],CO,,,,test
US20090012074A1,CC(C)(C)OC(=O)N[C@H]1CCc2cc(Br)ccc2C1.CCCBr>>CCCN(C(=O)OC(C)(C)C)[C@H]1CCc2cc(Br)ccc2C1,,CN(C)C=O,,O,[H-].[Na+],test
US20050154042A1,COC(Cl)Cl.Cc1ccnc(NC(=O)c2c(-c3ccc(F)cc3)c(-c3ccc(F)cc3)cn2C(C)C)n1>>Cc1ccnc(NC(=O)c2c(-c3ccc(F)cc3)c(-c3ccc(F)cc3)c(C=O)n2C(C)C)n1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20160038504A1,CC(C)O.Clc1cc(N2CCOCC2)c(Cl)nn1>>CC(C)Oc1nnc(Cl)cc1N1CCOCC1,,C1CCOC1,,[H-].[Na+],,test
US20130029962A1,CCOC(=O)CBr.OCc1ccc(Br)cn1>>COC(=O)COCc1ccc(Br)cn1,,C1CCOC1,,[H-].[Na+],,test
US03950528,CC(C)c1ccc(CNN)cc1.CCOC(=O)C=C(N)OCC>>CC(C)c1ccc(Cn2[nH]c(N)cc2=O)cc1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05021412,Cc1ccc(N(CCl)C(=O)Cl)cc1.FC(F)Oc1ccc(CNC(=S)NCC(F)(F)F)cc1>>Cc1ccc(N2CSC(=NCC(F)(F)F)N(Cc3ccc(OC(F)F)cc3)C2=O)cc1,,Cc1ccccc1,,,,test
US20030176418A1,ClCCCI.O=C1COc2cc([N+](=O)[O-])c(Cl)cc2N1>>O=C1COc2cc([N+](=O)[O-])c(Cl)cc2N1CCCCl,,CCCCCCC,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05387585,Nc1ccccc1-c1cc[nH]n1.O=C(Cl)CCl>>ClCc1nc2ccccc2c2ccnn12,,C1CCOC1,CCOCC,O=C([O-])[O-].[K+].[K+],,test
US20140336177A1,CC(C)(C)C(=O)Cl.Nc1ccc(Br)nn1>>CC(C)(C)C(=O)Nc1ccc(Br)nn1,,O,c1ccncc1,,,test
US20060235033A1,COc1cc2nccc(Oc3cc(C)c(N)cc3C)c2cc1OC.Cc1csc(C(C)N)n1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3cc(C)c(NC(=O)NC(C)c4nc(C)cs4)cc3C)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20130079338A1,FC(F)Oc1ccc(Nc2ncc(CCc3ccc4c(cnn4C4CCCCO4)c3)cn2)cc1Cl>>FC(F)Oc1ccc(Nc2ncc(CCc3ccc4[nH]ncc4c3)cn2)cc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150376208A1,CN1CC=C(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2[N+](=O)[O-])CC1>>CN1CCC(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2N)CC1,[Pd],CO,,,,test
US20150336942A1,CC(C)n1cc(-c2cc(Br)cnc2N)nn1.O=C(c1ccc(B(O)O)cc1Cl)N1CCOCC1>>CC(C)n1cc(-c2cc(-c3ccc(C(=O)N4CCOCC4)c(Cl)c3)cnc2N)nn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110275611A1,CC1(C)OB(c2ccc(C#N)c(F)c2)OC1(C)C.Cc1nc(C2CN(c3cc(Cl)nc(N)n3)CCO2)[nH]c1-c1ccccc1>>Cc1nc(C2CN(c3cc(-c4ccc(C#N)c(F)c4)nc(N)n3)CCO2)[nH]c1-c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US05998433,C=O.CNC.O=C1c2ccccc2S(=O)(=O)c2cc(C(=O)N3CCc4occc4C3)ccc21>>CN(C)Cc1cc2c(o1)CCN(C(=O)c1ccc3c(c1)S(=O)(=O)c1ccccc1C3=O)C2,,CC(=O)O,,,,test
US20140170207A1,CCCCCCCCCCCCOC(=O)C(C)N(C)C.CCS(=O)(=O)O>>CCCCCCCCCCCCOC(=O)C(C)N(C)C.CCS(=O)(=O)O,,CCOC(C)=O,,,,test
US20120165304A1,CC(=O)COC(=O)C1CN(C(=O)OCc2ccccc2)C1.CC(N)=O>>Cc1coc(C2CN(C(=O)OCc3ccccc3)C2)n1,,Cc1ccccc1C,,CCOCC,FB(F)F,test
US20150094296A1,CC(C)C1(C#N)CCN(c2ccnc(Cl)n2)C1=O.Nc1ccc(N2CCOCC2)cc1>>CC(C)C1(C#N)CCN(c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)C1=O,,CCCCO,,CC(=O)O,,test
US20040224974A1,CCc1nn2c(Br)cccc2c1NCC1CC1.O=CC1CCOCC1>>CCc1nn2c(Br)cccc2c1N(CC1CCOCC1)CC1CC1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20090143361A1,COc1ccc2nc(C)c3c(C)nc(Br)n3c2n1.OB(O)c1cccc(F)c1>>COc1ccc2nc(C)c3c(C)nc(-c4cccc(F)c4)n3c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[K+].[K+],test
US20080207654A1,CCCCc1nc(C)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.COc1ccc(C(=O)CBr)cc1>>CCCCc1nc(C)n(CC(=O)c2ccc(OC)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1,,CCOC(C)=O,,CN(C)C=O,[H-].[Na+],test
US20110028445A1,C[C@@H]1[C@H]2Cc3ccc(B4OC(C)(C)C(C)(C)O4)cc3[C@]1(C)CCN2C(=O)OC(C)(C)C.Cc1ccc(Cl)nn1>>Cc1ccc(-c2ccc3c(c2)[C@]2(C)CCN[C@H](C3)[C@H]2C)nn1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20140167002A1,Brc1cnc(Br)c2nsnc12.CCCC[Sn](CCCC)(CCCC)c1nc2ccccc2s1>>Brc1cnc(-c2nc3ccccc3s2)c2nsnc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20060247213A1,CC(C)C(NC(=O)OCc1ccccc1)P(O)O.CCO>>CCOP(O)C(NC(=O)OCc1ccccc1)C(C)C,,CCO,ClCCl,ClCCCl,,test
US20080255358A1,Cc1cccc(C)c1CNc1cc(-n2cc(C(=O)OCc3ccccc3)ccc2=O)cn2c(C)c(C)nc12.Cl>>Cc1cccc(C)c1CNc1cc(-n2cc(C(=O)O)ccc2=O)cn2c(C)c(C)nc12.Cl,,CO,O,[Na+].[OH-],,test
US20020183336A1,CC(=O)c1ccc(O)c(O)c1O.Cc1ccc(S(=O)(=O)OC[C@H]2CO2)cc1>>CC(=O)c1ccc2c(c1O)OC(CO)CO2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04014920,C=CCOc1ccccc1O.O=CC(Cl)(Cl)Cl>>C=CCOc1cc(C=O)ccc1O,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20070078135A1,CCNC1(C(N)=O)CCN(c2cnc(-c3ccc(Cl)cc3)c(Cl)n2)CC1.OB(O)c1ccncc1Cl>>CCNC1(C(N)=O)CCN(c2cnc(-c3ccc(Cl)cc3)c(-c3ccncc3Cl)n2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20120264735A1,CCN(CC)S(F)(F)F.CCOC(=O)Nc1cccc(C(O)c2nn(-c3ccccc3)ccc2=O)c1>>CCOC(=O)Nc1cccc(C(F)c2nn(-c3ccccc3)ccc2=O)c1,,ClCCl,,CO,,test
US20120083476A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)N2CC3(CN(Cc4ccccc4)C3)C2)cc1>>Cc1ccc(S(=O)(=O)N2CC3(CN(C(=O)OC(C)(C)C)C3)C2)cc1,[Pd],CO,,,,test
US20110263571A1,COC(=O)c1ccc(N2C(=O)OC[C@H]2C)cc1OC>>COc1cc(N2C(=O)OC[C@H]2C)ccc1C(=O)O,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20080312307A1,CCOC(=O)c1c2c(n(C)c1Nc1ccc(I)cc1F)C(=O)CCC2>>Cn1c(Nc2ccc(I)cc2F)c(C(=O)O)c2c1C(=O)CCC2,,CO,,Cl,[Na+].[OH-],test
US20100075953A1,C[C@H]1CN(c2ccc(OCCCN3CCCCC3)cc2)[C@H](C)CN1.O=C(Cl)N1CCOCC1>>C[C@@H]1CN(c2ccc(OCCCN3CCCCC3)cc2)[C@H](C)CN1C(=O)N1CCOCC1,,ClCCl,,CCN(CC)CC,,test
US20060079683A1,CC(=O)N(CC(=O)O)OC(C)(C)C.COc1ccc(Sc2ccc(CN3CCC(c4cc(N)ccc4C)CC3)cc2)cc1>>COc1ccc(Sc2ccc(CN3CCC(c4cc(NC(=O)CN(OC(C)(C)C)C(C)=O)ccc4C)CC3)cc2)cc1,CN(C)c1ccncc1,CN(C)C=O,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US20160214974A1,CC(C)(C)OC(=O)N1[C@H]2CC[C@@H]1CC(C(N)=S)(c1cncc(Br)c1)C2>>NC(=S)C1(c2cncc(Br)c2)C[C@@H]2CC[C@H](C1)N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150232445A1,CC(=O)Cl.Nc1c(I)cnn1C1CC1>>CC(=O)Nc1c(I)cnn1C1CC1,,ClCCl,,CC(C)NC(C)C,,test
US05081289,N=C(N)NCCCC(NC(CCC(=O)O)C(=O)O)C(=O)O>>NCCCC(NC(CCC(=O)O)C(=O)O)C(=O)O,,[Na+],[OH-],,,test
US06329550B1,CCOC(=O)C(NC(=O)OC(C)(C)C)C(=O)OCC>>CC(C)(C)OC(=O)NC(C(=O)O)C(=O)O,,CCO,,[Na+].[OH-],,test
US20110053941A1,CC(C)(C)OC(=O)NCC(O)c1ccccc1.CCOC(=O)N=NC(=O)OCC.O=C1c2ccccc2C(=O)N1O.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CN(CCC(ON1C(=O)c2ccccc2C1=O)c1ccccc1)C(=O)OC(C)(C)C,,C1CCOC1,O,,,test
US20050004163A1,CCNC(=O)c1ccc(C(=C2CC3CCC(C2)N3)c2cccnc2)cc1.O=C(Cl)Cc1ccccc1>>CCNC(=O)c1ccc(C(=C2CC3CCC(C2)N3C(=O)Cc2ccccc2)c2cccnc2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150239901A1,C[Si](C)(C)c1sc2cc3ccccc3cc2c1Sc1ccccc1>>c1ccc(Sc2csc3cc4ccccc4cc23)cc1,,O,,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100190766A1,COC(CC1(O)CC1)OC.CS(=O)(=O)Cl>>COC(CC1(OS(C)(=O)=O)CC1)OC,,ClCCl,,,,test
US05876984,C[C@H]1CC[C@H]2C(C)(C)[C@@H](O)CC[C@]23Oc2c(c(OCc4ccccc4)cc4c2CN(C(=O)OC(C)(C)C)C4=O)C[C@]13C>>C[C@H]1CC[C@H]2C(C)(C)C=CC[C@]23Oc2c(c(OCc4ccccc4)cc4c2CN(C(=O)OC(C)(C)C)C4=O)C[C@]13C,,c1ccccc1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05821241,COC(=O)[C@H](CNC(=O)c1cc2n(n1)CCN(CCC1CCN(C(=O)OC(C)(C)C)CC1)C2=O)NC(=O)OCc1ccccc1>>COC(=O)[C@@H](N)CNC(=O)c1cc2n(n1)CCN(CCC1CCN(C(=O)OC(C)(C)C)CC1)C2=O,[Pd],CO,,,,test
US20150232460A1,CC(C)(C)OC(=O)N[C@H]1CCC[C@@H]1Nc1ncc(C(F)(F)F)nc1Br.OB(O)C1CC1>>CC(C)(C)OC(=O)N[C@H]1CCC[C@@H]1Nc1ncc(C(F)(F)F)nc1C1CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20090186891A1,O=C(CNC(=O)c1ccc2nc(-c3c(Cl)cccc3Cl)[nH]c2c1)c1ccc(Cl)cc1>>Clc1ccc(-c2cnc(-c3ccc4nc(-c5c(Cl)cccc5Cl)[nH]c4c3)o2)cc1,,CCOC(C)=O,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US20040235858A1,NCC=CS(=O)(=O)N1CCN(c2ccc(F)cc2)CC1.O=C=Nc1ccc(F)cc1>>O=C(NCC=CS(=O)(=O)N1CCN(c2ccc(F)cc2)CC1)Nc1ccc(F)cc1,,ClCCl,,,,test
US20160200695A1,COc1ccc2nc(N)sc2c1.O=C(O)c1ccc(C(=O)c2ccccc2)cc1>>COc1ccc2nc(NC(=O)c3ccc(C(=O)c4ccccc4)cc3)sc2c1,,ClCCl,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20160016948A1,CCOC(C)=N.C[C@H](Nc1cc(Cl)ncc1N)c1ccc2[nH]cnc2c1>>Cc1nc2cnc(Cl)cc2n1[C@@H](C)c1ccc2[nH]cnc2c1,,CCO,,Cl,N,test
US20080242685A1,CC(C)(C)OC(=O)N1CCC(c2n[nH]c3c(C(N)=O)cc(Br)nc23)CC1.OB(O)c1ccccc1>>CC(C)(C)OC(=O)N1CCC(c2n[nH]c3c(C(N)=O)nc(-c4ccccc4)cc23)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05166204,Cc1cc2c(c3c1oc1ccccc13)C(=O)N(CCN(C)C)C2=O.Cl>>Cc1cc2c(c3c1oc1ccccc13)C(=O)N(CCN(C)C)C2=O.Cl,,ClC(Cl)Cl,,,,test
US20120094979A1,CC(C)Oc1ccc(-c2cnc(-c3ccc4c(c3)CCNCC4)s2)cc1Cl.Cl>>CC(C)Oc1ccc(-c2cnc(-c3ccc4c(c3)CCNCC4)s2)cc1Cl.Cl,,CO,,,,test
US20060025474A1,CCC(CC)(c1ccc(O)c(C)c1)c1ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1.CCOC(=O)c1ccc(CCl)o1>>CCOC(=O)c1ccc(COc2ccc(C(CC)(CC)c3ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c3)cc2C)o1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20100152450A1,CC(C)(C)OC(=O)N1CC[C@H]1COc1cncc(Br)c1.C[Sn](C)(C)[Sn](C)(C)C>>CC(C)(C)OC(=O)N1CC[C@H]1COc1cncc([Sn](C)(C)C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US04118380,COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)OCc1ccccc1>>COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN,[Pd],CC(=O)O,,,,test
US20060229336A1,COC(=O)c1cc(N)c(Cl)cc1F.CS(=O)(=O)Cl>>COC(=O)c1cc(NS(C)(=O)=O)c(Cl)cc1F,,ClCCl,,c1ccncc1,,test
US20110190269A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nc2cncc(-c3ccc(F)cc3)n2n1>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nc2n(n1)C(c1ccc(F)cc1)CNC2,[Pd],CCO,,,,test
US20090318690A1,CC(C)(C)OC(=O)N1CCC(CCc2noc3c(CO)c(O)ccc23)CC1.ClCc1ccc(Cl)c(Cl)c1>>CC(C)(C)OC(=O)N1CCC(CCc2noc3c(CO)c(OCc4ccc(Cl)c(Cl)c4)ccc23)CC1,,CCC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20160166560A1,CNC1CCN(C(=O)OC(C)(C)C)CC1.O=C(Cl)Cl>>CN(C(=O)Cl)C1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20150353489A1,CCCI.COC(=O)Cc1c[nH]c2ccc(O)cc12>>CCCOc1ccc2[nH]cc(CC(=O)OC)c2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20040181066A1,CSc1nccc(C(=O)CBr)n1.NC(N)=S>>Br.CSc1nccc(-c2csc(N)n2)n1,,CCO,,,,test
US20150175601A1,CC(C)(C)OC(=O)N1CCC(Nc2ccc([N+](=O)[O-])cc2)C(F)C1.Cl>>Cl.O=[N+]([O-])c1ccc(NC2CCNCC2F)cc1,,CO,,,,test
US03950320,BrBr.CC[C@@H](C(=O)[C@@H](C)[C@@H](O)[C@H](C)CCc1ccc(C)c(O)c1C(=O)O)[C@H]1O[C@](CC)([C@H]2CC[C@](O)(CC)[C@H](C)O2)C[C@@H]1C.[Na]>>CCC(C(=O)C(C)C(O)C(C)CCc1c(Br)cc(C)c(O)c1C(=O)O)C1OC(CC)(C2CCC(O)(CC)C(C)O2)CC1C.[Na],,S=C=S,,,,test
US05055458,O=C1c2ccccc2C(=O)N1O.OCC1COCOC1>>O=C1c2ccccc2C(=O)N1OCC1COCOC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160016951A1,CC(C)n1cc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)cn1.COC1CN(C(=O)c2ccc3cncc(Br)c3n2)C1>>COC1CN(C(=O)c2ccc3cncc(-c4ccc(-c5cnn(C(C)C)c5)cc4)c3n2)C1,,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20080004265A1,O=C1CCOCC1.OCCO>>C1CC2(CCO1)OCCO2,,c1ccccc1,,Cc1ccccc1S(=O)(=O)O,,test
US20140066426A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2c(-c3ccc(Cl)cc3)cc(C(F)(F)F)n2Cc2ccccc2)CC1(C)C>>CC1(C)CN(C(=O)c2c(-c3ccc(Cl)cc3)cc(C(F)(F)F)n2Cc2ccccc2)CCN1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20140057909A1,CC(C)(C)OC(=O)n1cc(/C=C/C(=O)O)c2ccccc21.CC(C)NNC(=O)c1ccccc1>>CC(C)N(NC(=O)c1ccccc1)C(=O)/C=C/c1cn(C(=O)OC(C)(C)C)c2ccccc12,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110183947A1,COC(=O)c1cccc(-c2nnc(CC(O)Cc3ccc(-c4ccccc4)cc3)o2)n1>>O=C(O)c1cccc(-c2nnc(CC(O)Cc3ccc(-c4ccccc4)cc3)o2)n1,,CO,ClCCl,,,test
US20060135517A1,Cc1cccc(-c2nc3ccc(C(=O)O)cn3c2-c2ccnc(N)n2)n1.NCCc1cccs1>>Cc1cccc(-c2nc3ccc(C(=O)NCCc4cccs4)cn3c2-c2ccnc(N)n2)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150087663A1,CC[C@H](N)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1.Nc1ncnc(Cl)c1C=O>>CC[C@@H](Nc1ncnc(N)c1C=O)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20090111864A1,N#Cc1ccc(N2C(=O)C3(CCC3)N(c3ccc(CCCC=O)cc3)C2=S)cc1C(F)(F)F.NCCN>>N#Cc1ccc(N2C(=O)C3(CCC3)N(c3ccc(CCCC4=NCCN4)cc3)C2=S)cc1C(F)(F)F,,ClCCl,,O=C1CCC(=O)N1Br,,test
US20040198751A1,CCOC(=O)c1cnc(SC)nc1N(C)N>>CSc1ncc2c(=O)[nH]n(C)c2n1,,CC(=O)O,,[K+].[OH-],,test
US20050266457A1,CCc1c(C(=O)NNC(C=C(C)C(C)(C)C)C(C)(C)C)ccc2c1OCCO2.COc1cc(C(=O)Cl)cc(OC)c1C>>CCc1c(C(=O)NN(C(=O)c2cc(OC)c(C)c(OC)c2)C(C=C(C)C(C)(C)C)C(C)(C)C)ccc2c1OCCO2,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20070224370A1,NC(=O)c1cccc(N)c1.O=C1OC(=O)C2C1C1C(=O)OC(=O)C21>>NC(=O)c1cccc(N)c1.O=C1OC(=O)C2C1C1C(=O)OC(=O)C21,,CN1CCCC1=O,,,,test
US20110130445A1,CCOC(=O)C=C(c1ccc(F)c([N+](=O)[O-])c1)C(F)(F)F>>CCOC(=O)CC(c1ccc(F)c(N)c1)C(F)(F)F,[Pd],CCO,,,,test
US06018046,COc1cc2c(=O)c(C)cn3c4cc(Br)ccc4c(c1)c23>>Cc1cn2c3cc(Br)ccc3c3cc(O)cc(c1=O)c32,,ClCCl,,BrB(Br)Br,,test
US06124347,COCOc1c(OC)cc(C(O)C[N+](=O)[O-])cc1OC>>COCOc1c(OC)cc(C(O)CN)cc1OC,[Pd],CCO,,,,test
US20160051523A1,CC(C)(C)OC(=O)Nc1nc(/C(=N/O[C@@H](COc2ccc(C(=N)NC3CCN(C(=O)OC(C)(C)C)CC3)cc2)C(=O)OC(c2ccccc2)c2ccccc2)C(=O)O)cs1.N[C@@H]1C(=O)N[C@@H]1Cn1cncn1>>CC(C)(C)OC(=O)Nc1nc(/C(=N/O[C@@H](COc2ccc(C(=N)NC3CCN(C(=O)OC(C)(C)C)CC3)cc2)C(=O)OC(c2ccccc2)c2ccccc2)C(=O)N[C@@H]2C(=O)N[C@@H]2Cn2cncn2)cs1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150203511A1,Cc1cc(-n2nc(C)c(C=O)c2C)ccc1OCc1c(C)cccc1-n1nnn(C)c1=O.NO>>Cc1cc(-n2nc(C)c(C=NO)c2C)ccc1OCc1c(C)cccc1-n1nnn(C)c1=O,,ClC(Cl)Cl,,Cl,c1ccncc1,test
US20110319445A1,CCOC(=O)Cc1ccc(OC)c(B2OC(C)(C)C(C)(C)O2)c1.N#Cc1cccnc1Cl>>CCOC(=O)Cc1ccc(OC)c(-c2ncccc2C#N)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20110312903A1,CC(C)(C)OC(=O)n1ncc2cc(B3OC(C)(C)C(C)(C)O3)ccc21>>CC(C)(C)OC(=O)n1ncc2cc(B(O)O)ccc21,,CC(C)=O,O,,,test
US20040147580A1,CC(C)(C)OC(=O)Nc1ccc(Br)cn1.COC(=O)CBr>>COC(=O)CN(C(=O)OC(C)(C)C)c1ccc(Br)cn1,,CN(C)C=O,,[H-].[Na+],,test
US20160022640A1,Cc1cc(CO)n(-c2ccccc2)n1.O=C1NC(=O)c2ccccc21>>Cc1cc(CN2C(=O)c3ccccc3C2=O)n(-c2ccccc2)n1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05130468,C=C[C@@H](O)[C@H](CC(C)C)NC(=O)OC(C)(C)C.CS(=O)(=O)Cl>>C=C[C@@H](OS(C)(=O)=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C,,CCOCC,ClCCl,CCN(CC)CC,,test
US20040229858A1,CC(C)(C)OC(=O)N1C[C@@H](N2C(=O)c3ccccc3C2=O)C[C@H]1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>CC(C)(C)OC(=O)N1C[C@@H](N)C[C@H]1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,CCO,,NN,O,test
US05624961,CNCCOc1cc(C)c(NC(C)=O)cc1C(C)C.COc1c(C)c(C)c(OC)c(CCl)c1C>>COc1c(C)c(C)c(OC)c(CN(C)CCOc2cc(C)c(NC(C)=O)cc2C(C)C)c1C,,CN(C)C=O,,CCN(CC)CC,,test
US20100160424A1,CN(C[C@H](CC1CCCCC1)NC(=O)c1cccc(C=O)c1)C(=O)OCC[Si](C)(C)C.Clc1cccc([Mg]Br)c1>>CN(C[C@H](CC1CCCCC1)NC(=O)c1cccc(C(O)c2cccc(Cl)c2)c1)C(=O)OCC[Si](C)(C)C,,C1CCOC1,,,,test
US05068333,O=P(Cl)(Cl)Cl.O=c1[nH]cc(Cl)cc1Br>>Clc1cnc(Cl)c(Br)c1,,CN(C)C=O,,,,test
US06133253,CC(C)(C)OC(=O)N1CC[C@H]1CO.Oc1cccnc1Cl>>CC(C)(C)OC(=O)N1CC[C@H]1COc1cccnc1Cl,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100173933A1,C=CCc1sc(COc2ccc(F)c(C(N)=O)c2F)nc1-c1ccc(OC)cc1>>CCCc1sc(COc2ccc(F)c(C(N)=O)c2F)nc1-c1ccc(OC)cc1,,CO,,,,test
US20110172236A1,COc1ccc(CN2CC(C(C)=O)CC2=O)cc1>>COc1ccc(CN2CC(C(C)O)CC2=O)cc1,,CO,,[BH4-].[Na+],,test
US06689909B1,ClI.Nc1cccc([N+](=O)[O-])c1Cl>>Nc1ccc(I)c([N+](=O)[O-])c1Cl,,CC(=O)O,,O=S([O-])[O-].[Na+].[Na+],,test
US20070179136A1,CC(C)(C)OC(=O)N1CCC(Cc2ccc(C(=O)Nc3cccc(C(N)=O)c3N)cc2)CC1>>NC(=O)c1cccc2[nH]c(-c3ccc(CC4CCNCC4)cc3)nc12,,CC(=O)O,,,,test
US20160090357A1,CCOC(=O)[C@H]1CCCN(C(=O)c2c(C)cccc2F)[C@H]1c1ccc(NC2CCCC2)cc1>>Cc1cccc(F)c1C(=O)N1CCC[C@H](C(=O)O)[C@@H]1c1ccc(NC2CCCC2)cc1,,O,,O=S(=O)(O)O,,test
US20120329780A1,COC(=O)c1cccc(-c2nc(Cl)c3nn(Cc4ccc(OC)cc4)cc3n2)c1.Nc1ccc2c(c1)NC(=O)CS2>>COC(=O)c1cccc(-c2nc(Nc3ccc4c(c3)NC(=O)CS4)c3[nH]ncc3n2)c1,C1COCCO1,CO,,Cl,,test
US20150361100A1,Nc1ncnc2c1c(I)nn2Cc1cc2ccccn2c1-c1ccccn1.OB(O)c1cc(O)cc(F)c1>>Nc1ncnc2c1c(-c1cc(O)cc(F)c1)nn2Cc1cc2ccccn2c1-c1ccccn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20130040933A1,COC(=O)c1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1.O=C1CCC(=O)N1Br>>COC(=O)c1cnc2c(c1)c(Br)cn2S(=O)(=O)c1ccccc1,,C1CCOC1,,,,test
US20050277670A1,C[C@H](CCNC(=O)OC(C)(C)C)N1CCC(Nc2ccc(O[Si](C)(C)C(C)(C)C)cc2)CC1.Cc1ccncc1C=O>>Cc1ccncc1CN(c1ccc(O[Si](C)(C)C(C)(C)C)cc1)C1CCN([C@H](C)CCN)CC1,,ClCCCl,,,,test
US20100009970A1,CC(=O)OC(C)=O.Nc1ccc2c(c1)C(=O)CCC2c1ccc(Cl)c(Cl)c1>>CC(=O)Nc1ccc2c(c1)C(=O)CCC2c1ccc(Cl)c(Cl)c1,,ClCCl,O,CCN(CC)CC,,test
US20060122399A1,CCc1cc(Br)ccc1CBr.CNC>>CCc1cc(Br)ccc1CN(C)C,,CO,,,,test
US05854234,CCC1CCN=C(OC)C1.[Cl-].[NH4+]>>CCC1CCNC(=N)C1.Cl,,CO,,,,test
US20100160309A1,C=C(C)c1nc2ccnc(OCCCC)c2c2cc(F)ccc12>>C=C(C)c1nc2cc[nH]c(=O)c2c2cc(F)ccc12,,CCOC(C)=O,O,O=S(=O)(O)O,[Na+].[OH-],test
US20120083006A1,CC(C)(C)OC(=O)NCCOc1cccc(N)c1.CS(=O)(=O)Nc1ccccc1Nc1nc(Cl)ncc1F>>CS(=O)(=O)Nc1ccccc1Nc1nc(Nc2cccc(OCCN)c2)ncc1F,,CCCCO,,,,test
US04379765,N#Cc1n[nH]cc1-c1ccc(Cl)cc1C(=O)c1ccccc1F>>Fc1ccccc1C1=NCc2n[nH]cc2-c2ccc(Cl)cc21,[Ni],CC(=O)O,,[NH4+].[OH-],,test
US20110190255A1,N#Cc1ccc(C(=O)CBr)cc1>>N#Cc1ccc(C(O)CBr)cc1,,C1CCOC1,,B,CSC,test
US20020030180A1,CCC1CCC(C2CCC(c3cc(F)c(N)c(F)c3)CC2)CC1.S=C(n1ccnc1)n1ccnc1>>CCC1CCC(C2CCC(c3cc(F)c(N=C=S)c(F)c3)CC2)CC1,,ClCCl,,,,test
US20080312270A1,COc1cc(CC(=O)O)ccc1Oc1ccc2[nH]c(C)cc2c1NS(=O)(=O)c1ccc(Cl)cc1Cl.O=C1CCC(=O)N1Cl>>COc1cc(CC(=O)O)ccc1Oc1ccc2[nH]c(C)c(Cl)c2c1NS(=O)(=O)c1ccc(Cl)cc1Cl,,CN(C)C=O,,,,test
US04877876,NC(=S)NCCCN1CCOCC1.O=C1c2ccc(F)cc2CC1Br>>Fc1ccc2c(c1)Cc1sc(NCCCN3CCOCC3)nc1-2,,CCO,,,,test
US04594347,C1CCNC1.CC1Cc2c(F)c(F)c(N)c3c(=O)c(C(=O)O)cn1c23>>CC1Cc2c(N3CCCC3)c(F)c(N)c3c(=O)c(C(=O)O)cn1c23,,CN1CCCC1=O,,,,test
US20160145245A1,CC(C)(C)OC(=O)N1CC[C@H](O)C1.COCCOCCOCCBr>>COCCOCCOCCO[C@H]1CCN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,[H-].[Na+],,test
US20090062311A1,COC(=O)c1ccc(OC)c(C)c1N.O=C(O)c1ccc(F)cc1>>COC(=O)c1ccc(OC)c(C)c1NC(=O)c1ccc(F)cc1,,ClCCl,c1ccncc1,O,,test
US20130252986A1,FC(F)(F)c1cc(Oc2ccc(CCBr)cc2)ccc1Cl.Oc1ccnc(O)c1>>O=c1cc(OCCc2ccc(Oc3ccc(Cl)c(C(F)(F)F)c3)cc2)cc[nH]1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110218192A1,CC(=O)c1ccccc1O.O=Cc1ccccc1>>O=C1CC(c2ccccc2)Oc2ccccc21,,CCO,O,,,test
US05883049,CI.Cc1cc(Cl)c(N2C(=O)C3=CCCCN3C2=O)cc1O>>COc1cc(N2C(=O)C3=CCCCN3C2=O)c(Cl)cc1C,,CC#N,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20090048258A1,CCCCc1ccc(C(=O)CBr)cc1.CCOC(=O)N=C=S.N=C(N)c1ccccc1>>CCCCc1ccc(C(=O)c2sc(N)nc2-c2ccccc2)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,Cl,test
US20060004069A1,CI.O=c1[nH]nc(Cc2ccc([N+](=O)[O-])cc2)o1>>Cn1nc(Cc2ccc([N+](=O)[O-])cc2)oc1=O,,O,,CN(C)C=O,[H-].[Na+],test
US20050277661A1,CCCC[Sn](/C=C/OCC)(CCCC)CCCC.COC(=O)c1ncc2c(ccn2Cc2ccc(F)cc2)c1OC(=O)C(F)(F)F>>CCO/C=C/c1c(C(=O)OC)ncc2c1ccn2Cc1ccc(F)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,CCN(CC)CC,,test
US05244910,CC(C)=C1C[C@H](O)[C@H](CC2CCCCC2)NC1=O>>CC(C)[C@@H]1C[C@H](O)[C@H](C2CCCCC2)NC1=O,[Pd],CCOC(C)=O,,,,test
US20070066624A1,CCc1nc(C(C)C)sc1C(=O)OC>>CCc1nc(C(C)C)sc1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20160068559A1,CC(C)(C)OC(=O)N(CCCNc1nc2cc(C(C)(C)C)ccc2[nH]1)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21>>CC(C)(C)c1ccc2[nH]c(NCCCNC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)nc2c1,,O,,O=C(O)C(F)(F)F,,test
US04578522,CO.COC(OC)OC.O=Cc1ccccc1Br>>COC(OC)c1ccccc1Br,Cl,CO,,,,test
US20160108056A1,CNS(=O)(=O)Nc1ccc2cc(C(=O)Nc3cccc(-c4ccc(F)cc4F)c3)n(C(=O)OC(C)(C)C)c2c1>>CNS(=O)(=O)Nc1ccc2cc(C(=O)Nc3cccc(-c4ccc(F)cc4F)c3)[nH]c2c1,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20150065482A1,COC(=O)C(NC(=O)c1cccc(Br)c1)c1cccnn1>>COC(=O)c1nc(-c2cccc(Br)c2)n2ncccc12,,CC#N,,O=P(Cl)(Cl)Cl,,test
US20130178460A1,N[C@H]1CCCC[C@H]1N.O=C(Nc1nc2ccccc2s1)c1csc2cnc(Cl)nc12>>N[C@H]1CCCC[C@H]1Nc1ncc2scc(C(=O)Nc3nc4ccccc4s3)c2n1,,C1CCOC1,CCOC(C)=O,,,test
US20140275071A1,C#CCO.FC(F)(F)Oc1cccc(I)c1>>OCC#Cc1cccc(OC(F)(F)F)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,,C1COCCN1,,test
US20110319431A1,COC(=O)c1cc(C(=O)c2ccc(OC)cn2)ccc1F>>COC(=O)c1cc(C(=O)c2ccc(O)cn2)ccc1F,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US05739333,COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(S(C)(=O)=O)nc1OCCOC1CCCCO1.OCCO>>COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(OCCO)nc1OCCOC1CCCCO1,,OCCO,,[H-].[Na+],[Cl-].[NH4+],test
US04128659,COc1ccc(Cl)c2ccccc12>>Oc1ccc(Cl)c2ccccc12,,O,,Br,CC(=O)O,test
US20100160308A1,N=C(N)SC(C(N)=O)C(=O)c1ccccc1C(F)(F)F>>NC(=O)c1sc(N)nc1-c1ccccc1C(F)(F)F,,CCO,,,,test
US04818272,COC(=O)Oc1cc(N2C(=O)OC(=C(C)C)C2=O)c(F)cc1Cl>>CC(C)=C1OC(=O)N(c2cc(O)c(Cl)cc2F)C1=O,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20080146572A1,CC(C)(C)OC(=O)N1CC=C(c2ccc(F)cc2)CC1>>Fc1ccc(C2=CCNCC2)cc1,,CCOCC,ClCCl,Cl,,test
US06083961,COc1ccc(COc2cccc([N+](=O)[O-])c2N)cc1>>COc1ccc(COc2cccc(N)c2N)cc1,[Fe],CC(=O)O,CCO,,,test
US20090275537A1,COC(=O)CC[C@@H](CO[Si](C)(C)C(C)(C)C)N(C)C(=O)NCc1cccc(F)c1F>>COC(=O)CC[C@H](C)N(C)C(=O)NCc1cccc(F)c1F,,CO,,Cl,,test
US05792860,CCCCCCCCCCCCBr.Oc1ccccc1O>>CCCCCCCCCCCCOc1ccccc1O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040157866A1,CC(=O)/C=C/c1ccc(C(F)(F)F)cc1.CCOC(=O)/C=C(/C)N>>CCOC(=O)c1c(-c2ccc(C(F)(F)F)cc2)cc(C)nc1C,,CCCCO,,,,test
US20040082780A1,C1COCCO1.Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.O=S(=O)(Oc1cc(C(F)(F)F)ccc1-c1cc(Oc2ccc3cccnc3c2)ncn1)C(F)(F)F>>C=Cc1cc(C(F)(F)F)ccc1-c1cc(Oc2ccc3cccnc3c2)ncn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,[Cl-].[Li+],,test
US03948885,Cc1ccc(S(=O)(=O)N=[N+]=[N-])cc1.NC(=O)CC(N)=O>>NC(=O)c1[nH]nnc1O,,CCO,,,,test
US20100016319A1,CCCCOC(=O)NN(C(=O)OCCCC)c1cccc(SC)c1.Cl>>CSc1cccc(NN)c1.Cl,,CO,,,,test
US20120040968A1,C1CC2(CCN1)OCCO2.Cc1cc([N+](=O)[O-])ccc1F>>Cc1cc([N+](=O)[O-])ccc1N1CCC2(CC1)OCCO2,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20160145245A1,CN(C(=O)C(c1ccccc1)c1ccccc1)[C@H](CN1CC[C@H](OC(=O)C(c2ccccc2)c2ccccc2)C1)c1cccc([N+](=O)[O-])c1>>CN(C(=O)C(c1ccccc1)c1ccccc1)[C@H](CN1CC[C@H](OC(=O)C(c2ccccc2)c2ccccc2)C1)c1cccc(N)c1,[Pd],C1CCOC1,,,,test
US05864039,CC(C)(C)OC(=O)NCC1CCN(CCCCN)C1.O=Cc1ccccc1>>CC(C)(C)OC(=O)NCC1CCN(CCCCNCc2ccccc2)C1,,CCO,,O,[BH4-].[Na+],test
US20080096914A1,COC(=O)CBr.Cc1ncc[nH]1>>COC(=O)Cn1ccnc1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160122342A1,C=O.CCN(c1cccc2c1CC=CCCc1cc(C)[nH]c(=O)c1CNC2=O)[C@@H]1CC[C@@H](N)CC1.CO>>CCN(c1cccc2c1CC=CCCc1cc(C)[nH]c(=O)c1CNC2=O)[C@@H]1CC[C@@H](N(C)C)CC1,,CO,,Cl,[BH3-]C#N.[Na+],test
US20160199372A1,Clc1cc(Br)c2nccn2n1.O=C1CCC(=O)N1Br>>Clc1cc(Br)c2ncc(Br)n2n1,,ClCCl,,,,test
US20130029968A1,CCOC1(OCC)CCN(Cc2ccccc2)CC1N.CCc1cc(OCOCC[Si](C)(C)C)c(F)cc1-c1ccc2c(C(=N)OC)nn(C3CCCCO3)c2c1>>CCOC1(OCC)CCN(Cc2ccccc2)CC1NC(=N)c1nn(C2CCCCO2)c2cc(-c3cc(F)c(OCOCC[Si](C)(C)C)cc3CC)ccc12,,CCO,,CC(=O)O,,test
US20060161024A1,O=C1C=C(COCc2ccccc2)CC1>>O=C1CC[C@@H](COCc2ccccc2)C1,,CCOCC,,Cl,,test
US20130131016A1,O=[N+]([O-])c1cc(F)c(F)c(Cl)c1>>Nc1cc(F)c(F)c(Cl)c1,[Fe],CO,,CC(=O)O,,test
US04226872,CC(C)C(Nc1ccc(C(F)(F)F)cc1Cl)C(=O)O.N#CC(O)c1cccc(Oc2cccc(F)c2)n1>>CC(C)C(Nc1ccc(C(F)(F)F)cc1Cl)C(=O)OC(C#N)c1cccc(Oc2cccc(F)c2)n1,,CCOCC,,,,test
US20110092415A1,O=C(Nc1cc(F)c(Br)cc1[N+](=O)[O-])C(F)(F)F>>Nc1cc(F)c(Br)cc1[N+](=O)[O-],,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20110015175A1,C=C1CCn2nc(Nc3ccc(-n4cnc(Cl)c4)c(OC)c3)nc2C(c2ccc(F)cc2)C1>>COc1cc(Nc2nc3n(n2)CCC(C)CC3c2ccc(F)cc2)ccc1-n1cnc(Cl)c1,[Pt],CCO,,O=C(O)C(F)(F)F,,test
US20080177303A1,C=CC(=O)OCCC(=O)O.O=S(Cl)Cl>>C=CC(=O)OCCC(=O)Cl,,ClCCl,,,,test
US20080306084A1,CN(COCCCOCc1ccccc1)S(=O)(=O)c1c(Cl)cc(Cl)cc1Cl>>CN(COCCCO)S(=O)(=O)c1c(Cl)cc(Cl)cc1Cl,[Pd],C1CCOC1,,,,test
US04366163,CC1(C)C=Cc2cc(C#N)c(N)cc2O1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC1(C)C=Cc2cc(C#N)c(NC(=O)C(F)(F)F)cc2O1,CN(C)c1ccncc1,ClC(Cl)Cl,,,,test
US05891909,Cc1cc(O)cc(OS(=O)(=O)c2cccc(C#N)c2)c1.OCCCO>>Cc1cc(OCCCO)cc(OS(=O)(=O)c2cccc(C#N)c2)c1,,C1CCOC1,CCCCCC,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20100273786A1,CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2c(C(F)(F)F)nc(C(=O)O)c2C1)Cc1cc(F)c(F)cc1F.Cl>>Cl.N[C@@H](CC(=O)N1CCn2c(C(F)(F)F)nc(C(=O)O)c2C1)Cc1cc(F)c(F)cc1F,,CCO,,,,test
US04000282,CC(C)(C)N1CC(CO)O[C@H]1c1ccccc1.N#Cc1cccnc1Cl>>CC(C)(C)N1CC(COc2ncccc2C#N)O[C@H]1c1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US20120295884A1,CC(C)(C)OC(=O)N1CC[C@H](O)[C@H]1C(=O)NCc1cccc(Cl)c1F.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CC[C@H](OS(C)(=O)=O)[C@H]1C(=O)NCc1cccc(Cl)c1F,,c1ccncc1,,,,test
US08178708B2,CC/C=C\C/C=C\C/C=C\CCCCCCC/C=C(\C)C(=O)OCC>>CC/C=C\C/C=C\C/C=C\CCCCCCC/C=C(\C)C(=O)O,,CO,O,Cl,[Li+].[OH-],test
US20050096337A1,CCOC(=O)COc1ccc(N(C)C(C)c2ccc(-c3cccc(C(F)(F)F)c3)nc2C)cc1CCCOC>>COCCCc1cc(N(C)C(C)c2ccc(-c3cccc(C(F)(F)F)c3)nc2C)ccc1OCC(=O)O,,C1CCOC1,CCO,[Na+].[OH-],,test
US20020040037A1,O=C(Cl)c1ccc(CCl)cc1.O=S(=O)(CCN1CC[C@H](Cc2ccccc2)[C@H](O)C1)c1ccc(O)cc1>>O=C(Oc1ccc(S(=O)(=O)CCN2CCC(Cc3ccccc3)C(O)C2)cc1)c1ccc(CCl)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US20130267592A1,CC(=O)CNCC(CNCC(=O)C1(c2ccc(-c3ccc(Cl)c(Cl)c3)c(F)c2)CC1)OC(C)=O.CC(=O)CNCC(CNCC(C)=O)OC(=O)C1(c2ccc(-c3ccc(Cl)c(Cl)c3)c(F)c2)CC1>>CC(=O)CNCC(CN(C)C(=O)C1(c2ccc(-c3ccc(Cl)c(Cl)c3)c(F)c2)CC1)OC(C)=O,CN(C)c1ccncc1,,,,,test
US20110288065A1,C[C@H](Nc1nc(Cl)cc(Cl)n1)c1ccc(F)cc1.OB(O)c1cncnc1>>C[C@H](Nc1nc(Cl)cc(-c2cncnc2)n1)c1ccc(F)cc1,,CCOC(C)=O,O,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20070066626A1,CC(C)(C)OC(=O)N1C[C@H](Oc2cc(F)cc([N+](=O)[O-])c2)C[C@H]1COS(C)(=O)=O.CN>>CNC[C@@H]1C[C@@H](Oc2cc(F)cc([N+](=O)[O-])c2)CN1C(=O)OC(C)(C)C,,C1CCOC1,CCOC(C)=O,,,test
US20110098251A1,O=C(Cl)N1CCOCC1.O=Cc1ccc(O)c(F)c1>>O=Cc1ccc(OC(=O)N2CCOCC2)c(F)c1,,O,,ClCCl,c1ccncc1,test
US04921851,O=C=NC(=O)CCl.OCCSc1ccc2nccn2n1>>O=C(CCl)NC(=O)OCCSc1ccc2nccn2n1,CCN(CC)CC,CN(C)C=O,ClCCl,,,test
US05618528,CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)O.Oc1cc(Cl)c(Cl)cc1Cl>>CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)Oc1cc(Cl)c(Cl)cc1Cl,,CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04785113,COc1c(C)cnc(C)c1C.OO>>COc1c(C)c[n+]([O-])c(C)c1C,[Pd],CC(=O)O,,,,test
US20090131458A1,BrBr.CC(C)COc1nc(N)c2ncn(CC3CCOCC3)c2n1>>CC(C)COc1nc(N)c2nc(Br)n(CC3CCOCC3)c2n1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US05556864,CN1CCCC1CCCl.COc1cc(CCc2ccccc2O)cc(OC)c1OC>>COc1cc(CCc2ccccc2OCCC2CCCN2C)cc(OC)c1OC,,CC(=O)N(C)C,,Cl,CC(C)(C)[O-].[K+],test
US20060211603A1,CC(C)(C)OC(=O)Cn1ncc2ccccc21>>O=C(O)Cn1ncc2ccccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050014765A1,CCN(CC)CC.CCN=C=NCCCN(C)C.Cc1nc(-c2ccccc2)c(C(=O)O)s1.On1nnc2ccccc21>>Cc1nc(-c2ccccc2)c(C(=O)N2CCN(c3cccc(C(N)=O)c3)CC2)s1,,ClCCl,,Cl,O,test
US20100113510A1,Nc1noc2ccccc12.O=C(Cl)CBr>>O=C(CCl)Nc1noc2ccccc12,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20110046122A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C1COCC(c2cc(N=C(c3ccccc3)c3ccccc3)ccc2F)(C2CC2)N1>>Fc1ccc(N=C(c2ccccc2)c2ccccc2)cc1C1(C2CC2)COCC(=S)N1,,C1CCOC1,CCOC(C)=O,,,test
US20050182108A1,Nc1ccc(O)cc1.O=C(O)CS>>O=C(CS)Nc1ccc(O)cc1,,Cl,,,,test
US20150368238A1,C=CC[C@@H](N[S@@](=O)C(C)(C)C)c1cc(F)ccc1OC1CCOC1.Cl>>C=CC[C@@H](N)c1cc(F)ccc1OC1CCOC1.Cl,,C1COCCO1,,,,test
US20060111375A1,CCC(O)c1cc(Cl)ccc1Oc1ccnc2cc(OC)c(OC)cc12>>CCC(=O)c1cc(Cl)ccc1Oc1ccnc2cc(OC)c(OC)cc12,,CS(C)=O,,O,,test
US05455260,Cl.c1ccc(C(NCCOCc2ccc(-c3nc4ccccc4o3)cc2)(c2ccccc2)c2ccccc2)cc1>>Cl.NCCOCc1ccc(-c2nc3ccccc3o2)cc1,,CCO,,,,test
US04216221,NCN1CCCC1=O.NCN1CCCCCCCC1=O.O=C(n1ccnc1)n1ccnc1>>O=C(NCN1CCCCCCCC1=O)NCN1CCCC1=O,,ClCCl,,,,test
US04992433,CCOC(=O)c1cccc(O)c1.ClCCCC1CCN(c2ccc(Cl)nn2)CC1>>CCOC(=O)c1cccc(OCCCC2CCN(c3ccc(Cl)nn3)CC2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100075968A1,COC(=O)C1CN(c2cccnc2)C(=O)N1C>>CN1C(=O)N(c2cccnc2)CC1C(=O)O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20110245255A1,CCN1CCN(c2nc(C)nc3[nH]c(-c4ccccc4Cl)nc23)CC1.COCBr>>CCN1CCN(c2nc(C)nc3c2nc(-c2ccccc2Cl)n3COC)CC1,,C1CCOC1,,[H-].[Na+],,test
US20090018345A1,CCOC(=O)n1nc(O)cc1C.Fc1cc(C(F)(F)F)cc(Cl)c1F>>CCOC(=O)n1nc(Oc2c(F)cc(C(F)(F)F)cc2Cl)cc1C,,CS(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100137587A1,CC(C)CN[C@H]1C[C@@H](C(=O)N2CCOCC2)CN(C(=O)OC(C)(C)C)C1.COCCCCn1c(C(Cl)(Cl)Cl)nc2cccc(C(=O)OC)c21>>COCCCCN1c2c(cccc2C(=O)OC)NC1C(=O)N(CC(C)C)[C@@H]1CNC[C@H](C(=O)N2CCOCC2)C1.Cl.Cl,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US05164510,CC(=O)OC(C)=O.O=[N+]([O-])c1ccc2c(c1)CCN2>>CC(=O)N1CCc2cc([N+](=O)[O-])ccc21,,c1ccncc1,,,,test
US04442115,CC(=O)c1cc(C)cc([N+](=O)[O-])c1O>>CC(=O)c1cc(C)cc(N)c1O,[Pt],CCO,,,,test
US20020042411A1,CCOC(=O)c1c(N(C)c2ccccc2[N+](=O)[O-])sc2ccccc12.CN1CCNCC1>>CN1CCN(C2=Nc3ccccc3N(C)c3sc4ccccc4c32)CC1,Cl[Ti](Cl)(Cl)Cl,COc1ccccc1,,,,test
US20100093722A1,OCC(O)CCc1cnccn1>>O=CCCc1cnccn1,,ClCCl,ClCCl,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20160060260A1,Cn1cnc(S(=O)(=O)Nc2cc3c(cc2Oc2cccc(OCCCCNC(=O)OC(C)(C)C)c2)n(C)c(=O)n3C)c1>>Cn1cnc(S(=O)(=O)Nc2cc3c(cc2Oc2cccc(OCCCCN)c2)n(C)c(=O)n3C)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090163512A1,CS(N)(=O)=O.Cc1ccc(F)cc1C1NC(=O)CC(c2cc(Br)ccc2OC(C)(C)C(=O)O)C12C(=O)Nc1cc(Cl)ccc12>>Cc1ccc(F)cc1C1NC(=O)CC(c2cc(Br)ccc2OC(C)(C)C(=O)NS(C)(=O)=O)C12C(=O)Nc1cc(Cl)ccc12,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,[H-].[Na+],test
US20020045747A1,C[C@H](N)C(=O)NC1N=C(c2ccccc2)c2ccccc2N(C)C1=O.O=C(Cl)CCl>>C[C@H](NC(=O)CCl)C(=O)NC1N=C(c2ccccc2)c2ccccc2N(C)C1=O,,ClCCl,,,,test
US20150045368A1,CC1(C)OC(=O)N(c2ccnc(NNC(=O)Nc3ccnc4cccnc34)c2)[C@H]1c1ccccc1>>CC1(C)OC(=O)N(c2ccn3c(Nc4ccnc5cccnc45)nnc3c2)[C@H]1c1ccccc1,,Cc1ccccc1,,O=P(Cl)(Cl)Cl,,test
US20060079484A1,CCOC(=O)C(Cc1cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(C)c1)C(O)([PH2]=O)C(NC(=O)OCc1ccccc1)C(C)C>>Cc1cc(CC(C(=O)O)C(O)([PH2]=O)C(NC(=O)OCc2ccccc2)C(C)C)cnc1NC(=O)OC(C)(C)C,,CC#N,,CO,[Li+].[OH-],test
US20130059834A1,CI.Clc1cc2[nH]nc(I)c2cc1Cl>>Cn1nc(I)c2cc(Cl)c(Cl)cc21,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20060247250A1,CN1CCN(C(=O)c2ccc(Nc3ncc(NC(=O)c4cc(O)ccc4Cl)cn3)cc2)CC1.COc1ccc(Cl)c(C(=O)Nc2cnc(Nc3cccc(C(=O)N(CCO)C(C)C)c3)nc2)c1>>CC(C)N(CCO)C(=O)c1cccc(Nc2ncc(NC(=O)c3cc(O)ccc3Cl)cn2)c1,,ClCCl,,BrB(Br)Br,,test
US04820834,CN1C(=O)C(N)N=C(c2ccccc2)c2ccccc21.C[C@@H](N=C=O)c1ccccc1>>C[C@@H](NC(=O)NC1N=C(c2ccccc2)c2ccccc2N(C)C1=O)c1ccccc1,,C1CCOC1,,,,test
US03949076,CC(=O)CCl.CC1=NCCN1>>CC(=O)CN1CCN=C1C,,CC(C)=O,,,,test
US20080076917A1,CC(C)(C)OC(=O)NCc1ncc(Br)s1.Cl>>Cl.NCc1ncc(Br)s1,,CCO,,C1COCCO1,,test
US20110112063A1,CC(C)c1noc(CCl)n1.Cc1cc(Nc2nc(Nc3cc(C)c(C4CCNCC4)cc3F)ncc2Cl)n[nH]1>>Cc1cc(Nc2nc(Nc3cc(C)c(C4CCN(Cc5nc(C(C)C)no5)CC4)cc3F)ncc2Cl)n[nH]1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20110195980A1,O=Cc1cc(Cl)ncc1[N+](=O)[O-].[Li]C>>CC(=O)c1cc(Cl)ncc1[N+](=O)[O-],Cl[Ti](Cl)(Cl)Cl,,,,,test
US20050154201A1,COC(=O)c1ccc(CBr)c([N+](=O)[O-])c1.Cc1cccnc1C1CCCC(c2ncccc2C)N1>>COC(=O)c1ccc(CN2C(c3ncccc3C)CCCC2c2ncccc2C)c([N+](=O)[O-])c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20040152714A1,Cc1nc(C)c(Cl)c(NCc2ccc(O)c(OCC3CC3)c2)n1.O=[N+]([O-])c1cnc2ccc(Cl)nn12>>Cc1nc(C)c(Cl)c(NCc2ccc(Oc3ccc4ncc([N+](=O)[O-])n4n3)c(OCC3CC3)c2)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05180742,CC1=C(C)C(=O)C(C(CCCCCC(=O)Oc2ccc([N+](=O)[O-])cc2)c2ccccc2)=C(C)C1=O.N>>CC1=C(C)C(=O)C(C(CCCCCC(N)=O)c2ccccc2)=C(C)C1=O,,C1CCOC1,,,,test
US20090054392A1,CC(C)(C)OC(=O)N1CC[C@H]2C(=O)OC(=O)[C@H]2C1.COc1ccc(CN)cc1>>COc1ccc(CN2C(=O)[C@@H]3CCN(C(=O)OC(C)(C)C)C[C@@H]3C2=O)cc1,,Cc1ccccc1,,,,test
US20050124555A1,BrC(Br)(Br)Br.Cc1ccc(CO)cc1[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>Cc1ccc(CBr)cc1[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150232465A1,CC(=O)N1c2cnc(-c3ccc(S(C)(=O)=O)cc3)cc2N(S(=O)(=O)c2ccc(C)cc2)C[C@@H]1C>>CC(=O)N1c2cnc(-c3ccc(S(C)(=O)=O)cc3)cc2NC[C@@H]1C,,ClCCl,,O=S(=O)(O)O,[Na+].[OH-],test
US20100143299A1,CN(C)CCNC(=O)c1ccc(B(O)O)cc1.Fc1ccc(CNc2nc(O[C@H]3CCOC3)c3cc(Br)ccc3n2)cc1>>CN(C)CCNC(=O)c1ccc(-c2ccc3nc(NCc4ccc(F)cc4)nc(O[C@H]4CCOC4)c3c2)cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04243678,CCOC(=O)CCCNc1ccccc1-c1ccccc1.O=C(Cl)c1cccc(C(F)(F)F)c1>>CCOC(=O)CCCN(C(=O)c1cccc(C(F)(F)F)c1)c1ccccc1-c1ccccc1,,c1ccccc1,,CCN(C(C)C)C(C)C,,test
US20060100207A1,C/C(N)=C\C#N.Cc1cccc(N)c1>>CC(=CC#N)Nc1cccc(C)c1,,O,,CC(=O)O,,test
US20130102618A1,COC(=O)C(C)(N)c1cc(Br)c(F)cc1F>>CC(N)(CO)c1cc(Br)c(F)cc1F,,CCO,,[BH4-].[Na+],,test
US20090131457A1,BrCc1ccccc1.O=Cc1cc(Br)cc(F)c1O>>O=Cc1cc(Br)cc(F)c1OCc1ccccc1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05118827,CC(=CCCC(C)=CCCC(C)=CC=C(C(C)C)C(C#N)O[Si](C)(C)C)CCl>>CC(=CCCC(C)=CCCC(C)=CC=C(C(C)C)C(O)C#N)CCl,,C1CCOC1,,Cl,,test
US20130178478A1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1N.Cc1cc(C)cc(Nc2cc(Cl)nnc2C(N)=O)c1>>Cc1cc(C)cc(Nc2cc(N[C@@H]3CCCC[C@@H]3NC(=O)OC(C)(C)C)nnc2C(N)=O)c1,,CCOC(C)=O,CN1CCCC1=O,,,test
US20060142337A1,CC(C)(C)OC(=O)N1CC[C@H](O)[C@H](c2ccccc2)C1.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(C)(C)OC(=O)N1CC[C@H](OC(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H](c2ccccc2)C1,CN(C)c1ccncc1,ClCCl,c1ccncc1,O,,test
US04064257,CC(C)C#CCCNC(=O)c1cnc(OCC2CO2)s1.CC(C)N>>CC(C)C#CCCNC(=O)c1cnc(OCC(O)CNC(C)C)s1,,CCO,,,,test
US20140296245A1,COC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@H]1c1ccc(F)cc1.O=S(=O)(NF)c1ccccc1>>COC(=O)C1(F)CN(C(=O)OC(C)(C)C)CCC1c1ccc(F)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05096899,CC(C)(CN=[N+]=[N-])C1=C(C(=O)OCc2ccc([N+](=O)[O-])cc2)N2C(=O)CC2O1>>CC(C)(CN)C1=C(C(=O)O)N2C(=O)CC2O1,[Pd],CCOC(C)=O,O,[H][H],,test
US20040116647A1,CC(=O)N(C)C.CC(CO)(CO)[N+](=O)[O-]>>CC(=O)N(C)C.CC(CO)(CO)[N+](=O)[O-],,Cc1ccccc1,,CO,,test
US20160272596A1,CC(=O)c1ccc(C(=O)N2C[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)N(CCc3cccc4ccccc34)c3ccccc32)cc1>>CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)c2ccc(C(C)=O)cc2)c2ccccc2N(CCc2cccc3ccccc23)C1=O,,CCOCC,,,,test
US20160016948A1,COC1CCN(c2nccc(Nc3cc4c(cn3)nc(-c3cnn(COCC[Si](C)(C)C)c3)n4C)n2)CC1>>COC1CCN(c2nccc(Nc3cc4c(cn3)nc(-c3cn[nH]c3)n4C)n2)CC1,,CO,Cl,,,test
US20100305154A1,C=CC=O.COc1cccc(N)c1C(=O)O>>COc1ccc2cccnc2c1C(=O)O,,C1COCCO1,,,,test
US20120309754A1,Cc1nc2ccccc2nc1-c1cc2nc(Cl)cc(Cl)n2n1.NC1CCOCC1>>Cc1nc2ccccc2nc1-c1cc2nc(Cl)cc(NC3CCOCC3)n2n1,,CN(C)C=O,O,CCN(CC)CC,,test
US20040127426A1,CCC(NC(=O)C(CC1(C)CCCC1)NC(=O)OCc1ccccc1)C(O)c1nc2ccccc2o1>>CC[C@H](NC(=O)[C@@H](N)CC1(C)CCCC1)C(O)c1nc2ccccc2o1,[Pd],,,,,test
US06060475,COC(=O)C(C)Oc1ccc(-c2ncccc2S(=O)(=O)N(C(=O)OCC(C)C)c2ncc(C)nc2OC)cc1>>COc1nc(C)cnc1NS(=O)(=O)c1cccnc1-c1ccc(OC(C)C(=O)O)cc1,,CO,COCCOC,[Na+].[OH-],,test
US20130172331A1,CCOC(=O)C(F)(F)[C@](CCOC)(N[S@@](=O)C(C)(C)C)c1nc(Br)ccc1F>>COCC[C@@](N[S@@](=O)C(C)(C)C)(c1nc(Br)ccc1F)C(F)(F)CO,,C1CCOC1,CCOC(C)=O,[BH4-].[Li+],,test
US06551682B1,CC(C)CCON=O.CCCOc1cccnc1N.Oc1ccc2ccccc2c1>>CCCOc1cccnc1N=Nc1c(O)ccc2ccccc12,,CCO,,C,C[O-].[Na+],test
US20110015157A1,C=CCC(O)(CCN[C@@H](C)c1cccc(F)c1)c1ccc(F)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>C=CC[C@]1(c2ccc(F)cc2)CCN([C@@H](C)c2cccc(F)c2)C(=O)O1,,ClCCl,,CCN(CC)CC,,test
US20050107360A1,COC(=O)Cl.Fc1cccc(COc2ccc3c(c2)CCNCC3)c1>>COC(=O)N1CCc2ccc(OCc3cccc(F)c3)cc2CC1,,CCN(CC)CC,,Cl,,test
US20150166564A1,C=O.CO.COCCNC[Si](C)(C)C>>COCCN(COC)C[Si](C)(C)C,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04800203,CCOC(=O)Nn1cccc1C(=O)c1ccc(Cl)cc1Cl>>O=c1c2ccc(Cl)cc2[nH]n2cccc12,,CCO,O,[K+].[OH-],,test
US20040152690A1,CC(=O)NCc1cnc(N2CCN[C@H](C)C2)c(Cl)c1.FC(F)(F)c1ccc2nc(Cl)[nH]c2c1>>CC(=O)NCc1cnc(N2CCN(c3nc4cc(C(F)(F)F)ccc4[nH]3)C(C)C2)c(Cl)c1,,CCO,,,,test
US20080114007A1,CN1CCC(c2ccc(N)cc2)CC1.COC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(S(C)(=O)=O)ncc2c1=O>>COC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(Nc3ccc(C4CCN(C)CC4)cc3)ncc2c1=O,,CC(=O)O,,,,test
US05428003,CC(C=NO)n1nnc2ccc(Oc3cc(F)c(C(F)(F)F)c(Cl)c3)cc21>>CC(C#N)n1nnc2ccc(Oc3cc(F)c(C(F)(F)F)c(Cl)c3)cc21,,CC(=O)OC(C)=O,,,,test
US20090093474A1,CC(=O)Nc1nc2c(s1)C(=O)C(C(=O)C1CCC1)CC2.COC(=O)c1ccc(NN)c(Cl)c1>>COC(=O)c1ccc(-n2nc(C3CCC3)c3c2-c2sc(NC(C)=O)nc2CC3)c(Cl)c1,,CC(=O)O,,,,test
US20110172209A1,CCc1ccc(Nc2nc(OCc3ccccc3)ccc2[N+](=O)[O-])cc1>>CCc1ccc(Nc2nc(OCc3ccccc3)ccc2N)cc1,[Zn],CC(=O)O,,,,test
US20150299230A1,CCS(=O)(=O)c1cc([N+](=O)[O-])c(C(=O)OC(C)(C)C)cc1F.OCCNCCO>>CCS(=O)(=O)c1cc([N+](=O)[O-])c(C(=O)OC(C)(C)C)cc1N(CCO)CCO,,CS(C)=O,,,,test
US20160145247A1,CC(C)(C)OC(=O)Cc1ccccc1OCc1cc(OC[C@H]2CCCO2)cc(B2OC(C)(C)C(C)(C)O2)c1.CC(C)(C)OC(=O)NCc1cccc(Cl)c1F>>CC(C)(C)OC(=O)Cc1ccccc1OCc1cc(OC[C@H]2CCCO2)cc(-c2cccc(CNC(=O)OC(C)(C)C)c2F)c1,,ClCCl,,,,test
US20110021496A1,CC(C)(C)OC(=O)N1C2CCC1CNC2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1C2CCC1CN(C(=O)C(F)(F)F)C2,,ClCCl,,CCN(CC)CC,,test
US05070086,CC(=O)OC(C)=O.O=c1c2cccnc2c(-c2ccccc2)c2n1CCN2>>CC(=O)N1CCn2c1c(-c1ccccc1)c1ncccc1c2=O,,c1ccncc1,,,,test
US06613942B1,Brc1ccc(CCOC2CCCCO2)c2ccccc12.CN(C)C=O>>O=Cc1ccc(CCOC2CCCCO2)c2ccccc12,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20020193367A1,CCN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3nncc3COC3CCCCO3)c2)cc1C>>CCN(C)c1cc2c(cc1C)NC(=O)CC(c1cccc(-n3nncc3CO)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130231333A1,COc1cccc2c1OCC2=O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1cccc2c(OS(=O)(=O)C(F)(F)F)coc12,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US05656645,C=CCn1cncc(C(=O)OCC)c1=O>>C=CCn1cncc(C(=O)O)c1=O,,CO,O,[Na+].[OH-],,test
US20140323303A1,CC#C[Sn](CCCC)(CCCC)CCCC.COC1=C(c2c(C)cc(Br)cc2C)C(=O)C(Cc2ccccn2)C1>>CC#Cc1cc(C)c(C2=C(OC)CC(Cc3ccccn3)C2=O)c(C)c1,,Cc1ccccc1,O,,,test
US20070208007A1,CCCN(CCC)CCCCN(C)Cc1ccc(CN(Cc2nccn2CC(=O)OCC)Cc2nccn2CC(=O)OCC)cc1>>CCCN(CCC)CCCCN(C)Cc1ccc(CN(Cc2nccn2CC(=O)O)Cc2nccn2CC(=O)O)cc1,,C1COCCO1,,Cl,,test
US20050038104A1,CC(C)(C)OC(=O)NC1CCN(c2cc(F)c(C#N)c(F)c2)CC1.OCCN1CCOCC1>>CC(C)(C)OC(=O)NC1CCN(c2cc(F)c(C#N)c(OCCN3CCOCC3)c2)CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20130252943A1,CCOC(=O)CC(=O)CCNC(=O)OCc1ccccc1.O=S(=O)(Cl)Cl>>CCOC(=O)C(Cl)C(=O)CCNC(=O)OCc1ccccc1,,ClCCl,,O=C([O-])O.[Na+],,test
US08586591B2,COC(=O)c1cc(Nc2cnccn2)nc(N[C@@H](C)c2ccc(F)cc2)c1>>C[C@H](Nc1cc(C(=O)O)cc(Nc2cnccn2)n1)c1ccc(F)cc1,,CCOC(C)=O,O,CO,[Na+].[OH-],test
US20080096860A1,CCOc1cc(NS(=O)(=O)N2CCN(C(=O)OC(C)(C)C)CC2)nc(SCc2cccc(F)c2F)n1>>CCOc1cc(NS(=O)(=O)N2CCNCC2)nc(SCc2cccc(F)c2F)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100249085A1,CC1(C)OB(C2=CCCCC2)OC1(C)C.Cc1ccc(Cn2nc(-c3nc(-c4ccc(Br)cc4)co3)cc2C)cc1>>Cc1ccc(Cn2nc(-c3nc(-c4ccc(C5=CCCCC5)cc4)co3)cc2C)cc1,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US05451596,Cl.c1ccc(C(NC2(COCc3ccc(-c4nc5ccccc5o4)cc3)CCCC2)(c2ccccc2)c2ccccc2)cc1>>Cl.NC1(COCc2ccc(-c3nc4ccccc4o3)cc2)CCCC1,,CCO,ClCCl,,,test
US20130202573A1,CC1(C)OB(c2ccc(C#N)c3ccccc23)OC1(C)C.CCOC(=O)C(C)(C)Sc1ncccc1Br>>CCOC(=O)C(C)(C)Sc1ncccc1-c1ccc(C#N)c2ccccc12,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US05942546,Cc1ccc(S(N)(=O)=O)cc1.S=C=Nc1ccc(Cl)cc1>>Cc1ccc(S(=O)(=O)NC(=S)Nc2ccc(Cl)cc2)cc1,,CC(C)=O,O,CC(=O)O,[Na+].[OH-],test
US04661502,CN(C)C(=O)Oc1cccnc1.O=C(OCCl)c1ccccc1>>CN(C)C(=O)Oc1ccc[n+](COC(=O)c2ccccc2)c1.[Cl-],,CCOCC,,,,test
US20140187553A1,Cc1ccc(S(=O)(=O)n2cc(I)c3cc(C(N)=NO)ccc32)cc1.O=C(Cl)C(Cl)(Cl)Cl>>Cc1ccc(S(=O)(=O)n2cc(I)c3cc(-c4noc(C(Cl)(Cl)Cl)n4)ccc32)cc1,,C1CCOC1,,CCN(CC)CC,O,test
US06235731B1,BrCc1ccccc1.C[C@H]1CN(C(=O)OC(C)(C)C)C[C@@H](C)N1>>C[C@H]1CN(C(=O)OC(C)(C)C)C[C@@H](C)N1Cc1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04439518,CCCCCC(C)(C)O.Oc1cccc(O)c1>>CCCCCC(C)(C)c1ccc(O)cc1O,,O,,CC(=O)O,O=S(=O)(O)O,test
US20120101136A1,CCOC(=O)CCCCBr.Cc1cc(O)ccc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1>>CCOC(=O)CCCCOc1ccc(-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)c(C)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06235771B1,CN(Cc1ccc(NC(=O)C2=Cc3cc(Br)ccc3S(=O)(=O)CC2)cc1)C1CCOCC1.[O-]B([O-])Oc1cc2ccccc2o1>>CN(Cc1ccc(NC(=O)C2=Cc3cc(-c4cc5ccccc5o4)ccc3S(=O)(=O)CC2)cc1)C1CCOCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[K+].[K+],test
US20070293515A1,CC(C)(C)OC(=O)N[C@H]1CC[C@H](C(=O)O/N=C(\N)Cc2ccccc2)C1>>CC(C)(C)OC(=O)N[C@H]1CC[C@H](c2nc(Cc3ccccc3)no2)C1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US04511569,N#Cc1cc2c([nH]c1=O)CCc1ccccc1-2>>N#Cc1cc2c(ccc3ccccc32)[nH]c1=O,,C1COCCO1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20070142446A1,CCc1sc(-c2cn(CC3CCCCC3)c3c(OC)cccc23)nc1CCl.CNC>>CCc1sc(-c2cn(CC3CCCCC3)c3c(OC)cccc23)nc1CN(C)C.Cl,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US05204477,C#Cc1ccc(CCC)cc1.CCOc1ccc(Br)cn1>>CCCc1ccc(C#Cc2ccc(OCC)nc2)cc1,,CCOCC,,CC[Mg]Br,,test
US05736539,COCCC[C@H]1CN(Cc2ccccc2)CCN1C(=O)OC(C)(C)C>>COCCC[C@H]1CNCCN1C(=O)OC(C)(C)C,[Pd],,,,,test
US20090156590A1,CCOC(=O)C(C)c1ccc2nc(NS(C)(=O)=O)sc2c1>>CC(C(=O)O)c1ccc2nc(NS(C)(=O)=O)sc2c1,,C1CCOC1,O,CC(=O)O,[Na+].[OH-],test
US08541521B2,COc1ccccc1-c1cccc(C(C)(O)c2ccccc2)c1OCc1ccccc1>>COc1ccccc1-c1cccc(C=Cc2ccccc2)c1OCc1ccccc1,,O,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US20090163524A1,CC(C)(C)OC(=O)NC(CCNC(=O)Oc1ccccc1)c1ccc(Cl)cc1.[NH4+]>>CC(C)(C)OC(=O)NC(CCNC(N)=O)c1ccc(Cl)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20100075961A1,CC(C)(C(N)=O)C1(c2ccc3c(cnn3-c3ccc(F)cc3)c2)CCOCC1>>CC(C)(CN)C1(c2ccc3c(cnn3-c3ccc(F)cc3)c2)CCOCC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140051672A1,CC(=O)ON1C(=O)CCC1=O.CN(c1ccc(-c2cc3ccc(OCCCN)cc3cc2O)nn1)C1CC(C)(C)NC(C)(C)C1>>CC(=O)NCCCOc1ccc2cc(-c3ccc(N(C)C4CC(C)(C)NC(C)(C)C4)nn3)c(O)cc2c1,,CS(C)=O,,CCOCC,,test
US20150274704A1,CN(c1nc(Nc2cnn(C)c2)ncc1Cl)C1CCC2(CC1)CCN(C(=O)OC(C)(C)C)C2>>CN(c1nc(Nc2cnn(C)c2)ncc1Cl)C1CCC2(CCNC2)CC1,,CCOC(C)=O,ClCCl,Cl,,test
US20040229891A1,Cc1cc(C)c(Nc2nc(C)ncc2S(=O)(=O)c2ccc(C#N)cc2)c(C)c1.NCCN>>Cc1cc(C)c(Nc2nc(C)ncc2S(=O)(=O)c2ccc(C3=NCCN3)cc2)c(C)c1,,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US20070249648A1,CC(C)(C)OC(=O)N1CCC2(CC1)CCN(C(=O)c1ccccc1)CC2>>O=C(c1ccccc1)N1CCC2(CCNCC2)CC1,,O=C(O)C(F)(F)F,,,,test
US06001849,C=O.Cl.Cl.Clc1cnc2cc([C@@H]3CCCN3)oc2c1>>CN1CCC[C@H]1c1cc2ncc(Cl)cc2o1.Cl.Cl,,O=CO,,O=C([O-])[O-].[K+].[K+],,test
US20110269769A1,CCC(=O)O.CS(=O)(=O)c1ccc(C(=O)CBr)cc1>>CCC(=O)OCC(=O)c1ccc(S(C)(=O)=O)cc1,,CO,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140024646A1,COC(=O)[C@@]12CNC[C@@H]1C[C@@H](NC(=O)OC(C)(C)C)C2.O=C(Cl)OCc1ccccc1>>COC(=O)[C@]12C[C@H](NC(=O)OC(C)(C)C)C[C@H]1CN(C(=O)OCc1ccccc1)C2,,ClCCl,,,,test
US20030087952A1,CN1C(=O)C[C@H](c2ccccc2)[C@@H]1CO.Oc1cccc(Cl)c1>>CN1C(=O)C[C@H](c2ccccc2)[C@@H]1COc1cccc(Cl)c1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100292128A1,CC(=O)[C@@H]1[C@H](C)C=CCC12CC2>>CC(=O)[C@H]1[C@H](C)C=CCC12CC2,,CCCCC,,CO,[Cl-].[NH4+],test
US20120214794A1,CC(C)(C)OC(=O)NCCC(c1ccc(Cl)cc1)c1nc(N2CCOCC2)sc1C(=O)O.Cl>>Cl.NCCC(c1ccc(Cl)cc1)c1nc(N2CCOCC2)sc1C(=O)O,,ClCCl,,C1COCCO1,,test
US20110105567A1,CCC(=O)CBr.COC(=O)CC(=O)C(C)C>>CCC(=O)CC(C(=O)OC)C(=O)C(C)C,,CO,,C[O-].[Na+],,test
US20100130492A1,BrCC1CC1.Clc1nc(N2CCOCC2)c2nc[nH]c2n1>>Clc1nc(N2CCOCC2)c2ncn(CC3CC3)c2n1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080113966A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)CNC1=S>>N[C@@H]1CC[C@@H](c2cccc(F)c2F)CNC1=S,,ClCCl,,O=C(O)C(F)(F)F,,test
US07495016B2,C[N+](=O)[O-].O=Cc1ccc(OCc2ccccc2)c(OC2CCCC2)c1>>O=[N+]([O-])C=Cc1ccc(OCc2ccccc2)c(OC2CCCC2)c1,,CC(=O)O,,,,test
US20070191336A1,CCOC(=O)c1cccc(NN)c1.N#CCC(=O)C(F)(F)F>>CCOC(=O)c1cccc(-n2nc(C(F)(F)F)cc2N)c1,,CCO,,Cl,,test
US20140296208A1,COCCOCCBr.COc1cc(SCCO)cc([N+](=O)[O-])c1>>COCCOCCOCCSc1cc(OC)cc([N+](=O)[O-])c1,,CN(C)C=O,,[H-].[Na+],,test
US05767268,CC(=O)OC[C@H](CCC(=O)NC[C@H]1O[C@@](O)(Cc2ccccc2)[C@H](NC(=O)c2ccc(-c3ccc(C(=O)N[C@@H]4[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](CNC(=O)CC[C@@H](COC(C)=O)OC(C)=O)O[C@@]4(O)Cc4ccccc4)cc3)cc2)[C@@H](OC(C)=O)[C@@H]1OC(C)=O)OC(C)=O>>O=C(CC[C@H](O)CO)NC[C@H]1O[C@@](O)(Cc2ccccc2)[C@H](NC(=O)c2ccc(-c3ccc(C(=O)N[C@@H]4[C@@H](O)[C@H](O)[C@@H](CNC(=O)CC[C@H](O)CO)O[C@@]4(O)Cc4ccccc4)cc3)cc2)[C@@H](O)[C@@H]1O,,C1COCCO1,,,,test
US20120202691A1,Cc1cc(-c2ccc(Cl)cc2)nn1C1C(=O)C/C(=C/c2ccc(F)cn2)C1=O>>Cc1cc(-c2ccc(Cl)cc2)nn1C1C(=O)CC(Cc2ccc(F)cn2)C1=O,[Pd],CO,,[H][H],,test
US20150376172A1,C[C@@]1(c2cc(Br)cs2)C[C@@H](C(F)(F)F)OC(N)=N1.N#Cc1ncc(B(O)O)cn1>>C[C@@]1(c2cc(-c3cnc(C#N)nc3)cs2)C[C@@H](C(F)(F)F)OC(N)=N1,,COCCOC,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,O=C([O-])[O-].[Na+].[Na+],test
US20080058369A1,CCOC(=O)C(C(=O)OCC)=C(Cl)CC.CCn1nccc1N>>CCOC(=O)c1c(CC)nc2c(cnn2CC)c1Cl,,Cc1ccccc1,,CCN(CC)CC,,test
US05298498,O=C(O)c1cc2ccccc2cc1C(=O)O>>OCc1cc2ccccc2cc1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070219239A1,CC(=O)c1ccc(O)c(C(=O)O)c1.CCI.CCN(C(C)C)C(C)C>>CCOC(=O)c1cc(C(C)=O)ccc1OCC,,CN(C)C=O,,,,test
US20030166639A1,COCCOc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3ccnc(C#N)c3)c2)cc1C(F)(F)F>>COCCOc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3ccnc(C#N)c3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US05644053,C[C@]1(/C=C/c2ccccn2)[C@H](C(=O)O)N2C(=O)C[C@H]2S1(=O)=O.[Na]>>C[C@]1(/C=C/c2ccccn2)[C@H](C(=O)O)N2C(=O)C[C@H]2S1(=O)=O.[Na],,O,,[Br-].[K+],,test
US20130065861A1,CC(C)(C)OC(=O)CCOCCOCCOCCN.CCCCCCCCCCCCOC[C@H](CSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)OCCCCCCCCCCCC>>CCCCCCCCCCCCOC[C@H](CSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NCCOCCOCCOCCC(=O)OC(C)(C)C)OCCCCCCCCCCCC,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06967198B2,Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O.O=C(O)c1cccnc1>>O=C(Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O)c1cccnc1,,CN(C)C=O,ClCCl,CCN(CC)CC,CO,test
US06001832,CCOP(=O)(CC(=O)NNc1nc2cc(-n3cc(C)nc3-c3ccccc3)c(C(F)(F)F)cc2n(OCc2ccccc2)c1=O)OCC>>CCOP(=O)(CC(=O)NNc1nc2cc(-n3cc(C)nc3-c3ccccc3)c(C(F)(F)F)cc2n(O)c1=O)OCC,[Pd],CCO,,,,test
US20150191452A1,Cc1ccc(CNC(=O)C(Br)CCBr)cc1F>>Cc1ccc(CN2CCC(Br)C2=O)cc1F,,C1CCOC1,,[H-].[Na+],,test
US20080255153A1,COC(=O)CC(=O)OC.FC(F)(F)Oc1cc(CBr)ccc1Cl>>COC(=O)C(Cc1ccc(Cl)c(OC(F)(F)F)c1)C(=O)OC,,C1CCOC1,CCOCC,Cl,[H-].[Na+],test
US06248888B1,COc1cc2nc(N3CCN(C(=O)C4CCCO4)CC3)nc(N)c2cc1OC.Cl>>COc1cc2nc(N3CCN(C(=O)C4CCCO4)CC3)nc(N)c2cc1OC.Cl,,O,,,,test
US04435406,Cc1ccc(CCl)nc1.Sc1nc2cc3c(cc2[nH]1)CCC3>>Cc1ccc(CSc2nc3cc4c(cc3[nH]2)CCC4)nc1,,O,,Cl,[Na+].[OH-],test
US04282388,CI.Fc1ccccc1CCl.O[C@H]1CC[C@H]1O>>CO[C@H]1CC[C@H]1OCc1ccccc1F,,CS(C)=O,,[Na+].[OH-],,test
US05354730,CCC(C)n1c(=O)sc2cc(F)c(-n3c(=O)cc(C(F)(F)F)[nH]c3=O)cc21.CI>>CCC(C)n1c(=O)sc2cc(F)c(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)cc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110144345A1,BrCc1ccc2ccccc2c1.COc1ccc(C(=O)c2cnn(C)c2O)c(Cl)c1N=C1CCCCS1=O>>COc1ccc(C(=O)c2cnn(C)c2OCc2ccc3ccccc3c2)c(Cl)c1N=C1CCCCS1=O,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US05516788,CC(C)c1ccc2c(c1)C1(C)Cc3ccccc3C1=N2.[Li]C>>CC(C)c1ccc2c(c1)[C@@]1(C)Cc3ccccc3[C@@]1(C)N2,,C1CCOC1,,CCOCC,[Cl-].[NH4+],test
US20080255083A1,BrP(Br)Br.Cc1cccnc1COc1ccn(CCc2ccc(CO)cc2)c(=O)c1>>Cc1cccnc1COc1ccn(CCc2ccc(CBr)cc2)c(=O)c1,,ClCCl,,COC(C)(C)C,,test
US05272163,O=[N+]([O-])c1ccc(S(=O)(=O)c2ccccn2)cc1>>Nc1ccc(S(=O)(=O)c2ccccn2)cc1,,CCO,,O=C([O-])O.[Na+],,test
US20150315209A1,CI.Cc1cnn(-c2ccncc2N2CCC3(CCNC3=O)CC2)c1>>Cc1cnn(-c2ccncc2N2CCC3(CCN(C)C3=O)CC2)c1,,O,,CN(C)C=O,[H-].[Na+],test
US04751233,ClC1CCCc2cccnc21.Sc1nc2ccccc2s1>>c1cnc2c(c1)CCCC2Sc1nc2ccccc2s1,,C1CCOC1,,[H-].[Na+],,test
US20120010209A1,O=c1cc(I)cnn1Cc1ccccc1.OB(O)c1ccc(F)cc1>>O=c1cc(-c2ccc(F)cc2)cnn1Cc1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20150166574A1,C1COCCN1.CCN(CC)CC.CS(=O)(=O)Cl.ClCCl.O.OCc1cn2cc(-c3ccccc3)sc2n1>>O=C(O)/C=C\C(=O)O.c1ccc(-c2cn3cc(CN4CCOCC4)nc3s2)cc1,,ClCCl,O,[Cl-].[Na+],,test
US20010034343A1,COc1ccc(CO)cc1.CS(=O)(=O)Cl>>COc1ccc(COS(C)(=O)=O)cc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20100249165A1,C#COC(=O)NC(=O)c1cc2ccccc2s1>>CCOC(=O)NC(=O)c1cc2ccccc2s1,[Pd],,,,,test
US04249937,CCC(=O)C1C(=O)CC(CCSc2ccc(Cl)cc2)CC1=O.CCON>>CCONC(CC)=C1C(=O)CC(CCSc2ccc(Cl)cc2)CC1=O,,CO,,,,test
US20060089359A1,Cc1cc(Nc2nn(-c3ccc(C(C)(C)C)cc3)c(=O)c3ccc(Br)cc23)n(C(C)(C)C)n1>>Cc1cc(Nc2nn(-c3ccc(C(C)(C)C)cc3)c(=O)c3ccc(Br)cc23)[nH]n1,,O=CO,,,,test
US04021434,CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1.CCOC(C)Cl>>CCOC(=O)C1=C(C)N(C(C)OCC)C(C)=C(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1,,C1CCOC1,,[H-].[Na+],,test
US05298655,CC(C)(C)[Si](C)(C)Cl.CCOP(=O)(CO)OCC>>CCOP(=O)(CO[Si](C)(C)C(C)(C)C)OCC,,ClCCl,O,CCN(CC)CC,CN(C)c1ccccn1,test
US20130210809A1,CCN(CC)CC.CN(C)C=O.CNOC.COc1ccc(Cn2cc(I)c(C(=O)O)n2)cc1.COc1ccc(Cn2ncc(I)c2C(=O)O)cc1.O=C(Cl)C(=O)Cl>>COc1ccc(Cn2cc(I)c(C(=O)N(C)OC)n2)cc1.COc1ccc(Cn2ncc(I)c2C(=O)N(C)OC)cc1,,CN(C)C=O,ClCCl,Cl,,test
US06043246,COc1ccc(-c2cc(NC(=O)Oc3ccccc3)n[nH]2)cc1.c1ccc(N2CCNCC2)cc1>>COc1ccc(-c2[nH]nc(N3CCN(c4ccccc4)CC3)c2N=C=O)cc1,,ClC(Cl)Cl,,CCN(CC)CC,CCOCC,test
US20120202785A1,C[C@H](N)c1nc2ccc(F)cc2n1-c1ccccn1.N#Cc1c(N)ncnc1Cl>>C[C@H](Nc1ncnc(N)c1C#N)c1nc2ccc(F)cc2n1-c1ccccn1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20140256733A1,COc1cc2cc(B3OC(C)(C)C(C)(C)O3)n(S(=O)(=O)c3ccc(C)cc3)c2cc1OC.Clc1ccc2ncc(I)n2n1>>COc1cc2cc(-c3cnc4ccc(Cl)nn34)n(S(=O)(=O)c3ccc(C)cc3)c2cc1OC,[Pd],CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20100210647A1,COC(=O)c1cc2cc(CBr)cc([N+](=O)[O-])c2n1C(=O)OC(C)(C)C.O=C1NC(=O)c2ccccc21>>COC(=O)c1cc2cc(CN3C(=O)c4ccccc4C3=O)cc([N+](=O)[O-])c2n1C(=O)OC(C)(C)C,,CN(C)C=O,,O,[K],test
US20090275590A1,Cl.Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CCN(C(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C)C2>>Cl.Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CCN(C(=O)[C@@H]1CCCN1)C2,,CCOCC,CO,,,test
US20060276464A1,ClCCN1CCOCC1.O=S(=O)(NC1CCNCC1)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F>>O=S(=O)(NC1CCN(CCN2CCOCC2)CC1)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F,,CCO,,CCN(CC)CC,Cl,test
US20080300242A1,CC(C)(C)OC(=O)N1CCN(CCF)CC1>>FCCN1CCNCC1,,CO,Cl,O=C([O-])[O-].[K+].[K+],,test
US06288103B1,COC(=O)c1cc2c(OC(C)=O)cccc2n1S(=O)(=O)c1ccc(Cl)c(Cl)c1>>COC(=O)c1cc2c(O)cccc2n1S(=O)(=O)c1ccc(Cl)c(Cl)c1,,CO,,Cl,O=C([O-])O.[Na+],test
US04017515,CC(C)(C)ON.O=C(O)C(=O)c1cc2ccccc2s1>>CC(C)(C)ON=C(C(=O)O)c1cc2ccccc2s1,,CCO,,Cl,[Na+].[OH-],test
US20020099241A1,COc1cc(CCNC(=O)[C@@H](N)C(C)C)ccc1OCCCc1ccc(Cl)cc1.CS(=O)(=O)Cl>>COc1cc(CCNC(=O)[C@](N)(C(C)C)S(C)(=O)=O)ccc1OCCCc1ccc(Cl)cc1,,C1COCCO1,,CCN(CC)CC,O,test
US20160207885A1,CN.O=Cc1ccc(C(=O)O)c(F)c1>>CNC(=O)c1ccc(C=O)cc1F,,CN(C)C=O,ClCCl,O,O=S(Cl)Cl,test
US20060135578A1,COC(=O)c1cc(-c2nc(COc3ccc(CCl)cc3OC)c(C)o2)ccc1OS(C)(=O)=O.O=Cc1cn(-c2ccccc2)nc1O>>COC(=O)c1cc(-c2nc(COc3ccc(COc4nn(-c5ccccc5)cc4C=O)cc3OC)c(C)o2)ccc1OS(C)(=O)=O,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20140088078A1,CCN1CCC(Cc2cc(F)ccc2S(=O)(=O)Cl)CC1.COC(=O)c1c(N)ccc2c1OCC1CC21>>CCN1CCC(Cc2cc(F)ccc2S(=O)(=O)Nc2ccc3c(c2C(=O)OC)OCC2CC32)CC1,,ClCCl,c1ccncc1,,,test
US20140163024A1,CC(C)CNc1ccc(F)cc1.O=S(=O)(Cl)c1ccc(Cl)nc1>>CC(C)CN(c1ccc(F)cc1)S(=O)(=O)c1ccc(Cl)nc1,,ClCCl,O,c1ccncc1,O=C([O-])O.[Na+],test
US20120010228A1,COC(=O)CCCCN1CN(c2ccccc2)C2(CCN(C(=O)OC(C)(C)C)CC2)C1=O>>COC(=O)CCCCN1CN(c2ccccc2)C2(CCNCC2)C1=O,,C1COCCO1,,Cl,,test
US20100210680A1,COc1cccc2c1CO[C@@]1(C)CN(C(=O)OC(C)(C)C)C[C@@H]21.Cl>>COc1cccc2c1CO[C@@]1(C)CNC[C@@H]21.Cl,,C1COCCO1,CO,,,test
US20030114457A1,BrBr.COc1ccc(CC(=O)O)cc1>>COc1ccc(CC(=O)O)cc1Br,,CC(=O)O,,,,test
US04977272,C1CCOC1.C=CCOC(=O)[C@@H](N)C(C)C.COC(OC)OC.NO.[N-]=C=O.c1ccncc1>>C=CCOC(=O)C(NC(=O)Nc1ccc(C=NO)cc1)C(C)C,,CO,,Cl,,test
US20150210630A1,CC(C)(C)ON=C(CBr)c1ncc(Cl)cc1Cl.O=C1NC(=O)c2ccccc21>>CC(C)(C)ON=C(CN1C(=O)c2ccccc2C1=O)c1ncc(Cl)cc1Cl,,CN(C)C=O,,O,[K],test
US20160016908A1,CC(=O)Cl.C[C@@H]1[C@@H](Nc2cccc(C(=O)O)n2)c2cc(C#N)ccc2N[C@H]1C1CC1>>CC(=O)N1c2ccc(C#N)cc2[C@H](Nc2cccc(C(=O)O)n2)[C@@H](C)[C@@H]1C1CC1,,ClCCl,,,,test
US05110347,Cc1cc(Br)c(N)c([N+](=O)[O-])c1.N#CN>>Cc1cc(Br)c2nc(N)n[n+]([O-])c2c1,,CC(=O)O,Cl,,,test
US20040067939A1,CC(C)I.Cc1ccc2c(C(=O)C(F)(F)F)c[nH]c2c1>>Cc1ccc2c(C(=O)C(F)(F)F)cn(C(C)C)c2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150344490A1,Cn1nccc1-c1ccc(OCc2ccccc2)cc1>>Cn1nccc1-c1ccc(O)cc1,[Pd],CCO,,[H][H],,test
US04914112,CC(c1cccc(C(=O)c2ccccc2)c1)c1nc(N)no1.CON>>CON=C(c1ccccc1)c1cccc(C(C)c2nc(N)no2)c1,,c1ccncc1,,Cl,,test
US20100022583A1,C=C(C)CC(C(=O)OC)c1cc(-c2ccc(C(F)(F)F)cc2)nc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1>>COC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)nc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1,[Pd],CO,,,,test
US20090247757A1,C#Cc1ccccc1.CC(C)C=O.c1ccc(CNCc2ccccc2)cc1>>CC(C)C(C#Cc1ccccc1)N(Cc1ccccc1)Cc1ccccc1,,Cc1ccccc1,,,,test
US20110086854A1,CC(C)(C)CC1CNC(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.COC(=O)c1ccc(NC(=O)n2ccnc2)cc1OC>>COC(=O)c1ccc(NC(=O)N2C[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)cc1OC,,ClCCl,,,,test
US06218397B1,CC(=O)OCc1c2ccccc2c(COC(C)=O)c2ccccc12.CSc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(C)nc(N(CCCO)Cc3ccccc3)c12>>CSc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(C)nc(N(CCCOC(C)=O)Cc3ccccc3)c12,,ClCCl,,CCN(CC)CC,,test
US20050065210A1,CN(C[C@@H]1CC[C@@H](C(=O)O)CC1)c1ncc(Br)cn1.NC1CC1>>CN(C[C@@H]1CC[C@@H](C(=O)NC2CC2)CC1)c1ncc(Br)cn1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US08158638B2,COc1c(C)cnc(Cn2nc(CCO)c3c(Cl)nc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nc32)c1C.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1c(C)cnc(Cn2nc(CCOS(=O)(=O)c3ccc(C)cc3)c3c(Cl)nc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nc32)c1C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20110183983A1,CC(C)(C)OC(=O)Nc1ccc(Oc2ccnc3c2cc(-c2ccccc2)n3COCC[Si](C)(C)C)c(F)c1>>Nc1ccc(Oc2ccnc3[nH]c(-c4ccccc4)cc23)c(F)c1,,CO,,Cl,,test
US04540703,CCNCC.O=C(O)CCCCc1nnnn1-c1ccccc1>>CCN(CC)C(=O)CCCCc1nnnn1-c1ccccc1,,CN(C)C=O,,CC(C)COC(=O)Cl,CCN(CC)CC,test
US20050261294A1,N#CCCN.O=Cc1cccs1>>N#CCCNCc1cccs1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20120253035A1,CC(C)(C)COS(=O)(=O)c1cccc(-c2ccc(F)c([C@@]3(C)NC(=O)COC(C)(C)C3(F)F)c2)c1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)COS(=O)(=O)c1cccc(-c2ccc(F)c([C@@]3(C)NC(=S)COC(C)(C)C3(F)F)c2)c1,,C1COCCO1,,,,test
US20110003793A1,Fc1ccc(CCCl)cc1.O=C1CNCCN1>>O=C1CN(CCc2ccc(F)cc2)CCN1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20090054435A1,COc1ccc(C(=O)c2ccc(Cl)nc2)c(OC(C)(C)C(=O)OC(C)(C)C)c1.Oc1ccccc1>>COc1ccc(C(=O)c2ccc(Oc3ccccc3)nc2)c(OC(C)(C)C(=O)OC(C)(C)C)c1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20050165050A1,COc1ccc(F)cc1C(C)(C)CC(O)(CNc1cccc2nc(CN3CCOCC3)ccc12)C(F)(F)F>>CC(C)(CC(O)(CNc1cccc2nc(CN3CCOCC3)ccc12)C(F)(F)F)c1cc(F)ccc1O,,ClCCl,,BrB(Br)Br,,test
US05006563,CCOC(=O)C(F)(F)Cl.Cl[Mg]Cc1ccccc1>>O=C(Cc1ccccc1)C(F)(F)Cl,,C1CCOC1,CCOCC,[Cl-].[NH4+],,test
US20030114668A1,CC(N)(CO)CO.O=Cc1ccccc1>>CC(CO)(CO)NCc1ccccc1,,CCOC(C)=O,CO,[Na+].[OH-],,test
US04450272,N#Cc1ccc(N=C=S)cc1.c1cnc(N2CCNCC2)cn1>>N#Cc1ccc(NC(=S)N2CCN(c3cnccn3)CC2)cc1,,CCOCC,,,,test
US20140249024A1,O=C1CCC(=O)N1Cl.c1ccc(-c2cnc(-c3cccnc3)s2)nc1>>Clc1nc(-c2cccnc2)sc1-c1ccccn1,,CN(C)C=O,,,,test
US04374829,CCOC(=O)C(=O)Cc1ccc(C#N)cc1>>N#Cc1ccc(CC(=O)C(=O)O)cc1,,[Na+],[OH-],,,test
US20030181359A1,CSCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)OCc1ccccc1>>CSCC[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)OCc1ccccc1,,CN(C)C=O,,C1CCNCC1,,test
US20080090851A1,CC(C)OC(=O)C(C)(C)N1CCC(NCc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)CC1.O=C(O)Cn1c(CCc2cccc(F)c2F)nc(=O)c2cccnc21>>CC(C)OC(=O)C(C)(C)N1CCC(N(Cc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)C(=O)Cn2c(CCc3cccc(F)c3F)nc(=O)c3cccnc32)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130274244A1,CB(O)O.CC(C)c1cccc(Cn2nc(Br)c3c([N+](=O)[O-])cccc32)n1>>Cc1nn(Cc2cccc(C(C)C)n2)c2cccc([N+](=O)[O-])c12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20120277244A1,CC(N)(C(=O)O)c1cc(Br)ccc1F>>CC(N)(CO)c1cc(Br)ccc1F,,C1CCOC1,,B,CSC,test
US20160083368A1,N[C@@H](Cc1cc(F)cc(F)c1)c1nc(C#CC2(O)CCC2)ccc1Br.O=C(Cn1nc(C(F)(F)F)c2c1C(F)(F)[C@@H]1C[C@H]21)ON1C(=O)CCC1=O>>O=C(Cn1nc(C(F)(F)F)c2c1C(F)(F)[C@@H]1C[C@H]21)N[C@@H](Cc1cc(F)cc(F)c1)c1nc(C#CC2(O)CCC2)ccc1Br,,CC#N,CCOC(C)=O,,,test
US20160016944A1,Cn1c(/C(=N\OCc2cccc(NC(=O)OC(C)(C)C)n2)c2ccccc2)noc1=O>>CNC(=N\O)/C(=N\OCc1cccc(NC(=O)OC(C)(C)C)n1)c1ccccc1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20060247309A1,CCOC(=O)Cc1cccc(OCc2c(C)cccc2C)c1>>Cc1cccc(C)c1COc1cccc(CC(=O)O)c1,,CCO,,Cl,[Na+].[OH-],test
US05948907,C[O-].O=C(Cl)C(=O)Cl.c1ccc2[nH]ccc2c1>>COC(=O)C(=O)c1c[nH]c2ccccc12,,CCOCC,,O,,test
US04778932,O=S(=O)(O)c1ccccc1.c1ccccc1>>O=S(=O)(c1ccccc1)c1ccccc1,,c1ccccc1,,,,test
US20030158256A1,C=CCOC(=O)c1cccc(CI)c1.CC(C)(C)OC(=O)N[C@@H](CO)C(=O)O>>C=CCOC(=O)c1cccc(COC[C@H](NC(=O)OC(C)(C)C)C(=O)O)c1,,CN(C)C=O,,Cl,[H-].[Na+],test
US04426382,CCC=CCC(=O)Cl.COc1cc2nc(N3CCNCC3)nc(N)c2cc1OC>>CCC=CCC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1,,CCN(CC)CC,,C1CCOC1,Cl,test
US20090048320A1,CCc1cccc(C#C[Si](C)(C)C)c1>>C#Cc1cccc(CC)c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20110118354A1,CC(=O)CC(C)CC(=O)O>>CC1=CC(C)CC(=O)O1,,c1ccccc1,,O=S(Cl)Cl,,test
US04288592,CC(=O)OC(C)=O.Nc1ccccc1>>CC(=O)Nc1ccccc1,,ClCCl,,,,test
US20160046596A1,CN(C)C=O.COCOc1cccnc1-c1cccnc1>>COCOc1c(C=O)ccnc1-c1cccnc1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20150141401A1,NNC(=O)OCc1ccccc1.O=C(Cl)c1ccco1>>O=C(NNC(=O)c1ccco1)OCc1ccccc1,,C1CCOC1,CCOC(C)=O,O,O=C([O-])O.[Na+],test
US20120071535A1,CON.O=Cc1cc(Br)cc(F)c1F>>CO/N=C/c1cc(Br)cc(F)c1F,,COCCOC,,Cl,O=C([O-])[O-].[K+].[K+],test
US20120277224A1,COC(=O)CC(=O)c1ccc2c(c1)CCO2.Nc1[nH]nc(O)c1-c1ccccn1>>O=c1cc(-c2ccc3c(c2)CCO3)[nH]c2c(-c3ccccn3)c(O)nn12,,CC(=O)O,,,,test
US04468392,CCCCS.O=C1CCC(Cl)CCN1>>CCCCSC1CCNC(=O)CC1,,CCO,,C,C[O-].[Na+],test
US05883106,COc1cccc(C2(C#N)CCOCC2)c1>>N#CC1(c2cccc(O)c2)CCOCC1,,ClCCl,,BrB(Br)Br,,test
US20020037907A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC1CCN(Cc2ccccc2)CC1>>CC(C)(C)OC(=O)NCC1CCNCC1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US08501931B2,C1COCCN1.CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@H](n2cnc3c(On4nnc5ccccc54)ncnc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C>>CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@H](n2cnc3c(N4CCOCC4)ncnc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C,,COCCOC,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020165282A1,CCCCCCCNCC1(c2ccc(CC(OCC)C(=O)OC)cc2)CC1.O=C=Nc1ccc(F)cc1F>>CCCCCCCN(CC1(c2ccc(CC(OCC)C(=O)OC)cc2)CC1)C(=O)Nc1ccc(F)cc1F,,Cc1ccccc1,,CCN(C(C)C)C(C)C,Cl,test
US05618821,COS(C)(=O)=O.Cc1cc(-c2noc(C(F)(F)F)n2)cc(C)c1OCCCc1cccnc1>>CS(=O)(=O)[O-].Cc1cc(-c2noc(C(F)(F)F)n2)cc(C)c1OCCCc1ccc[n+](C)c1,,ClCCl,,,,test
US20030236287A1,Cc1cc(O[Si](C)(C)C(C)(C)C)ccc1NC(=S)Nc1nc(C(F)(F)F)cs1>>Cc1cc(O)ccc1NC(=S)Nc1nc(C(F)(F)F)cs1,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130190356A1,CC(C)CNCc1cnc(Br)s1.O=S(=O)(Cl)Cc1ccccc1>>CC(C)CN(Cc1cnc(Br)s1)S(=O)(=O)Cc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20030018034A1,CC(=O)OC(C)=O.NCc1ccc(C(=O)O)cc1>>CC(=O)NCc1ccc(C(=O)O)cc1,,CCOC(C)=O,,Cl,[Na+].[OH-],test
US20130060041A1,CCC1C=NNC1.NCC(F)(F)F.S=C(n1ccnc1)n1ccnc1>>CCC1C=NN(C(=S)NCC(F)(F)F)C1,,CC#N,,,,test
US07300947B2,C1CCOC1.CC1(C)OCC(O)O1.CS(=O)(=O)Cl>>CC1(C)OCC(OS(C)(=O)=O)CO1,,C1CCOC1,,CCN(CC)CC,[Cl-].[NH4+],test
US20050240049A1,CC(=O)NC1Cc2ccc(S(=O)(=O)Cl)cc2C1>>CC(=O)NC1Cc2ccc(S)cc2C1,[Zn],CC#N,,Cl,,test
US20120108592A1,CC(=O)Oc1ccccc1C(=O)Nc1cccc(F)c1>>O=C(Nc1cccc(F)c1)c1ccccc1O,,Cl,,,,test
US20100273770A1,COC(=O)CCC1c2ccc(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)cc2CCCN1C(=O)OC(C)(C)C>>COC(=O)CCC1NCCCc2cc(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)ccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130289238A1,CCOC(=O)c1nnc(-c2ccccc2)s1>>OCc1nnc(-c2ccccc2)s1,,CC(=O)O,,CO,[BH4-].[Na+],test
US04005150,CC(C)=CCCC(C)CCBr.O=[N+]([O-])c1ccc(S)cc1>>CC(C)=CCCC(C)CCSc1ccc([N+](=O)[O-])cc1,,CO,,[Na],,test
US07109229B2,COC(=O)C(=O)OC.COc1cc(Br)c2c(ccn2C)c1>>COC(=O)C(=O)c1cc(OC)cc2ccn(C)c12,,C1CCOC1,,[Li]C(C)(C)C,,test
US04352808,O=C1c2ccc(Cl)cc2SCC1Br>>OC1c2ccc(Cl)cc2SCC1Br,,CO,,[BH4-].[Na+],,test
US06262278B1,CC(C)(C)[Si](C)(C)OCC1CO1>>CC(C)(C)[Si](C)(C)OC[C@@H]1CO1,CC(=O)O,C1CCOC1,,O,,test
US20070232583A1,CC(C)(C)NS(=O)(=O)c1ccc(-c2cn(-c3nc(-c4ccc(Cl)cc4)cc(C(F)(F)F)n3)cn2)cc1>>NS(=O)(=O)c1ccc(-c2cn(-c3nc(-c4ccc(Cl)cc4)cc(C(F)(F)F)n3)cn2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080234277A1,N=C(COCCc1ccc2ccccc2c1)NC(=O)c1nccnc1Cl>>O=c1[nH]c(COCCc2ccc3ccccc3c2)nc2nccnc12,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US05866684,CC(CCC1(C)OB(C(Cl)Cl)OC1(C)C)CC(=O)OC(C)(C)C.CC[Mg]Br>>CCC(Cl)B1OC(C)(C)C(C)(CCC(C)CC(=O)OC(C)(C)C)O1,,C1CCOC1,CCOC(C)=O,,,test
US06169091A,Clc1ncnc2ccsc12.Nc1ccc(OCc2cccs2)cc1>>Cl.c1csc(COc2ccc(Nc3ncnc4ccsc34)cc2)c1,,CC(C)O,,,,test
US20100105654A1,CS(=O)(=O)Cl.NC1CN(C(c2ccccc2)c2ccccc2)C1>>CS(=O)(=O)NC1CN(C(c2ccccc2)c2ccccc2)C1,,ClCCl,,CCN(CC)CC,,test
US20030232832A1,CC[Mg]Br.COC(=O)c1ccn2nc(C=O)n(Cc3ccccc3)c(=O)c12>>CCC(O)c1nn2ccc(C(=O)OC)c2c(=O)n1Cc1ccccc1,,ClCCl,,,,test
US04789750,Cc1c(C)c2c(c(C)c1OCc1ccccc1)CC[C@@](C)(CC(=O)O)O2.O=C(Cl)C(=O)Cl>>Cc1c(C)c2c(c(C)c1OCc1ccccc1)CC[C@@](C)(CC(=O)Cl)O2,,Cc1ccccc1,,O,,test
US20070166228A1,CC(C)(C)OC(=O)CN(CCN(CC(=O)OC(C)(C)C)CC(Cc1ccc(NC(=O)OC(C)(C)C)cc1)N(CC(=O)OC(C)(C)C)Cc1ccccc1)Cc1ccccc1>>CC(C)(C)OC(=O)CNCCN(CC(=O)OC(C)(C)C)CC(Cc1ccc(NC(=O)OC(C)(C)C)cc1)NCC(=O)OC(C)(C)C,[Pd],CO,,O=C[O-].[NH4+],,test
US20150175602A1,CC(C)Nc1nc2c(nc1N1CCC(Oc3ccc(F)cc3F)CC1)CNCC2.COC(=O)Cl.O=C(O)C(F)(F)F>>COC(=O)N1CCc2nc(NC(C)C)c(N3CCC(Oc4ccc(F)cc4F)CC3)nc2C1.O=C(O)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20040034005A1,CN1CCc2ccc(Cl)c3c4c(n(c23)CC1)CCC4>>Clc1ccc2c3c1c1c(n3CCNCC2)CCC1,,CC(Cl)Cl,,CC(Cl)OC(=O)Cl,,test
US20070049603A1,COc1ccc(-c2sc3cnccc3c2Nc2ccc3c(c2)CCC3=NO[Si](C)(C)C(C)(C)C)cc1>>COc1ccc(-c2sc3cnccc3c2Nc2ccc3c(c2)CCC3=NO)cc1,,ClCCl,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04489075,COc1cc2ncnc(N3CCC(CCBr)CC3)c2cc1OC.O=S1(=O)N=CC=CN1>>COc1cc2ncnc(N3CCC(CCN4C=CC=NS4(=O)=O)CC3)c2cc1OC,,CN(C)C=O,,[H-].[Na+],,test
US20040049037A1,CON(C)C(=O)C(C)(C)NC(=O)OC(C)(C)C>>CON(C)C(=O)C(C)(C)N,,ClCCl,O=C(O)C(F)(F)F,,,test
US20080015199A1,COC(=O)N=C(SC)C(=Nc1ccc(-c2noc(C)n2)cc1)c1cc(OC)c2c(c1F)OCCO2.NNc1ncccn1>>COc1cc(C(Nc2ccc(-c3noc(C)n3)cc2)c2nn(-c3ncccn3)c(=O)[nH]2)c(F)c2c1OCCO2,,CN(C)C=O,,CCN(CC)CC,,test
US20080139546A1,CO.Cc1ccc2c3c(ccc2n1)OCC(N(CCC=O)C(=O)OC(C)(C)C)O3.Fc1ccc2c(c1)CCN2>>Cc1ccc2c3c(ccc2n1)OC[C@H](CN(CCCN1CCc2cc(F)ccc21)C(=O)OC(C)(C)C)O3,,CC(=O)O,,[Na+].[OH-],,test
US20130096118A1,N#Cc1cccc(N)c1F.O=C(Cl)OCc1ccccc1>>N#Cc1cccc(NC(=O)OCc2ccccc2)c1F,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20130040984A1,CC(C)(C)n1cc(-c2cc3ncccc3c(NC[C@]3(F)CCCNC3)n2)cn1>>CC(C)(C)n1cc(-c2cc3ncccc3c(NC[C@]3(F)CCCNC3)n2)cn1,,O,,Cl,Cl,test
US20070179060A1,C[Si](C)(C)c1c(F)cc(Cl)c(C=O)c1F.ClI>>O=Cc1c(Cl)cc(F)c(I)c1F,,ClCCl,,,,test
US20050277670A1,CC(=O)Nc1ccc(N(Cc2cccc(C#N)c2)C2CCN(C(C)CCNC(=O)c3c(C)cccc3C)CC2)cc1>>Cc1cccc(C)c1C(=O)NCCC(C)N1CCC(N(Cc2cccc(C#N)c2)c2ccc(N)cc2)CC1,,CO,,Cl,,test
US20150018422A1,CCOC(=O)CCc1ccnc(CO)c1.COc1ccc(F)c(-c2ccc(O)cc2CC(C)(C)C)c1>>CCOC(=O)CCc1ccnc(COc2ccc(-c3cc(OC)ccc3F)c(CC(C)(C)C)c2)c1,,C1CCOC1,Cc1ccccc1,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060241115A1,Nc1ccon1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(Nc1ccon1)Oc1ccc([N+](=O)[O-])cc1,,C1CCOC1,,,,test
US20100298301A1,CN=C=O.NC(=O)c1nc(-c2c(F)cccc2F)oc1-c1ccc(N2CCNCC2)cc1>>CNC(=O)N1CCN(c2ccc(-c3oc(-c4c(F)cccc4F)nc3C(N)=O)cc2)CC1,,ClCCl,,,,test
US20140343036A1,CCOC(=O)c1cnc(N)c2nc(-c3cccc(F)c3)ccc12>>Nc1ncc(C(=O)O)c2ccc(-c3cccc(F)c3)nc12,,C1CCOC1,,CO,[Na+].[OH-],test
US20160214971A1,COc1cc(C(=O)NS(C)(=O)=O)ccc1-c1cnc(F)c(Cl)c1.COc1nccc(O)c1Cl>>COc1cc(C(=O)NS(C)(=O)=O)ccc1-c1cnc(Oc2ccnc(OC)c2Cl)c(Cl)c1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150225394A1,CC(C)(C)[Si](C)(C)OC1CCC(N2CC(CC#N)(N3CCC(N(C(=O)C(F)(F)F)[C@@H]4C[C@H]4c4ccccc4)CC3)C2)CC1>>N#CCC1(N2CCC(N(C(=O)C(F)(F)F)[C@@H]3C[C@H]3c3ccccc3)CC2)CN(C2CCC(O)CC2)C1,,C1CCOC1,,C1COCCO1,Cl,test
US20150239884A1,C=CCN.COC(=O)c1nc(SC)ncc1Br>>C=CCNC(=O)c1nc(SC)ncc1Br,,CO,,,,test
US20150175619A1,CON(C)C(=O)C1C2CC(O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)CC21.C[Mg]Br>>CC(=O)C1C2CC(O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)CC21,,C1CCOC1,,[Cl-].[NH4+],,test
US20040209905A1,C#CCN.COc1cc2ncnc(Oc3ccc(N)c(F)c3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>C#CCNC(=O)Nc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1F,,CCN(CC)CC,ClC(Cl)Cl,Cl,O=C([O-])O.[Na+],test
US20120252801A1,CC(C)(C)OC(=O)CBr.CC1(C)CN(Cc2ccccc2)CC(=O)O1>>CC(C)(C)OC(=O)CC1C(=O)OC(C)(C)CN1Cc1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20130345252A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=C1c2ccccc2-c2c1c1ccccc1c(=O)n2CCO>>CC(=O)OCCn1c2c(c3ccccc3c1=O)C(=O)c1ccccc1-2,,ClCCl,,CCN(CC)CC,,test
US20120077799A1,Fc1ccc(Br)c(C(F)(F)F)c1.Nc1ncccc1-c1ccc(O)cc1>>Nc1ncccc1-c1ccc(Oc2ccc(Br)c(C(F)(F)F)c2)cc1,,CCOC(C)=O,CS(C)=O,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20040122244A1,COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)NC3CC3)c2)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2ccc(O)c(C(=O)NC3CC3)c2)=C(C)C1=O,,CO,O,O=C([O-])O.[Na+],,test
US20150368265A1,CCOC(=O)c1c(C2CC2)oc2cc(N)c(Br)cc12>>Nc1cc2oc(C3CC3)c(C(=O)O)c2cc1Br,,C1COCCO1,O,Cl,[Li]O,test
US20070054884A1,O=[N+]([O-])O.Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl>>O=[N+]([O-])c1cc(Oc2ccc(Cl)cc2Cl)c(O)cc1Cl,,ClCCl,,,,test
US20110172442A1,COC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C=Cc1ccccc1OC(C)=O>>COc1ccc(C[C@H](NC(=O)C=Cc2ccccc2O)C(=O)O)cc1,,CO,,[Na+].[OH-],,test
US20130129839A1,Nc1c(F)cccc1Cl.S=C(Cl)Cl>>Fc1cccc(Cl)c1N=C=S,,Clc1ccccc1,,CN(C)C=O,,test
US20130072494A1,Cc1csc(N)c1C(N)=O.O=C(O)Cc1ccc(OCCn2ccnc2)cc1>>Cc1csc(NC(=O)Cc2ccc(OCCn3ccnc3)cc2)c1C(N)=O,,CCN(CC)CC,,,,test
US20160221941A1,CC(CO)(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O.CI>>COC(=O)C(C)(CO)NC(=O)OCC1c2ccccc2-c2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050043278A1,CCOC(=O)C(C)(C)CCCCC(=O)CCCCC(C)(C)C(=O)OCC>>CCOC(=O)C(C)(C)CCCCC(O)CCCCC(C)(C)C(=O)OCC,,CO,,O,[BH4-].[Na+],test
US20100137313A1,CN(C)CCCN.Clc1ncc(Br)c(Cl)n1>>CN(C)CCCNc1nc(Cl)ncc1Br,,C1COCCO1,,CCOC(C)=O,,test
US20120172345A1,CCOC(=O)c1sc(-c2ccncc2)cc1C(O)c1ccc2ccccc2c1>>CCOC(=O)c1ccc(-c2ccncc2)s1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20100167929A1,CC(C)(C)C(=O)Oc1c(-c2c(F)ccc(F)c2Cl)c(=O)[nH]c2nccnc12.FCCBr>>CC(C)(C)C(=O)Oc1c(-c2c(F)ccc(F)c2Cl)c(=O)n(CCF)c2nccnc12,,CN(C)C=O,,[I-].[K+],,test
US20080227839A1,Fc1ccccc1I.c1ccc(-c2cc[nH]n2)cc1>>Fc1ccccc1-n1ccc(-c2ccccc2)n1,I[Cu]I,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20160052930A1,COC(=O)c1cc(NC(=O)OC(C)(C)C)cc(C(=O)OC)n1>>COC(=O)c1cc(NC(=O)OC(C)(C)C)cc(CO)n1,,ClCCl,,CO,[BH4-].[Na+],test
US20100004220A1,O=c1[nH]c2c(c3ccccc13)Cc1cc(CBr)ccc1-2>>O=C1N=CC=c2ccc3c(c21)C=c1ccccc1=3,,CCO,CN(C)C=O,,,test
US20080045521A1,COC(=O)[C@H](Cc1ccc(C#CCC(C)O)cn1)NC(=O)OC(C)(C)C>>COC(=O)[C@H](Cc1ccc(CCCC(C)O)cn1)NC(=O)OC(C)(C)C,[Pd],CO,,,,test
US20040138229A1,O=C(OCc1ccccc1)c1cc(OCc2ccccc2)c2ccccc2n1>>O=C(O)c1cc(OCc2ccccc2)c2ccccc2n1,,C1CCOC1,,[Li+].[OH-],,test
US20150073011A1,C=CCONS(=O)(=O)c1ccccc1[N+](=O)[O-].CN(C)C(=O)C1=C[C@@H](CO[Si](C)(C)C(C)(C)C)N(C(=O)OC(C)(C)C)C[C@H]1O>>C=CCON([C@H]1CN(C(=O)OC(C)(C)C)[C@H](CO[Si](C)(C)C(C)(C)C)C=C1C(=O)N(C)C)S(=O)(=O)c1ccccc1[N+](=O)[O-],,Cc1ccccc1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04118567,NC(=S)Cc1ccccn1.NC1CC1>>S=C(Cc1ccccn1)NC1CC1,,O,,,,test
US20130280245A1,COc1ccccc1-c1nnc2ccc(Br)cn12.Cc1ccc(B(O)O)cc1>>COc1ccccc1-c1nnc2ccc(-c3ccc(C)cc3)cn12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120110702A1,CCN=C=O.Cc1nn(-c2cccnc2)cc1N>>CCNC(=O)Nc1cn(-c2cccnc2)nc1C,,ClCCl,,,,test
US06387938B1,CCOC(=O)c1cccc(N)c1N.O=Cc1ccccc1>>CCOC(=O)c1cccc2nc(-c3ccccc3)[nH]c12,,CO,,Cl,,test
US20070254869A1,CC(=O)CC(=O)N1CCCC(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(C)=O)c2ccc(Cl)cc21.NO>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(c2cc(C)no2)c2cc(Cl)ccc21,,CO,O,Cl,CC(=O)[O-].[Na+],test
US20070037789A1,COc1ccc(CN2CCC(F)(F)C[C@@H](NS(=O)(=O)CCC(F)(F)F)C2=O)c(OC)c1.COc1ccc(CO)cn1>>COc1ccc(CN2CCC(F)(F)C[C@@H](N(Cc3ccc(OC)nc3)S(=O)(=O)CCC(F)(F)F)C2=O)c(OC)c1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090018132A1,CC(OCC1(c2ccc(F)cc2)CCN(C(=O)OC(C)(C)C)CC1)c1cc(Cl)cc2c1n(COCC[Si](C)(C)C)c(=O)n2C>>CC(OCC1(c2ccc(F)cc2)CCN(C(=O)OC(C)(C)C)CC1)c1cc(Cl)cc2c1[nH]c(=O)n2C,,CCOCC,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20050288258A1,Cc1ncc(COP(=O)(O)O)c(C=O)c1O.Nc1ccc2ccccc2c1>>Cc1ncc(COP(=O)(O)O)c(C=Nc2ccc3ccccc3c2)c1O,,CCO,O,,,test
US20110237584A1,C[Si](C)(C)C(F)(F)F.O=Cc1cccs1>>OC(c1cccs1)C(F)(F)F,,C1CCOC1,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20120035195A1,CC(=O)OC1CCc2cc(Cl)cnc21>>OC1CCc2cc(Cl)cnc21,,CO,O,[Na+].[OH-],,test
US20130324576A1,CC(C)(C)OC(=O)N1CCC(O)CC1.Fc1cc(Cl)cnc1F>>CC(C)(C)OC(=O)N1CCC(Oc2ncc(Cl)cc2F)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US20060009497A1,COC(=O)C1=C(c2ccc(CCCOc3cc(F)ccc3F)cc2)CCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CCC(c2ccc(CCCOc3cc(F)ccc3F)cc2)=C(C(=O)O)C1,,CCO,,Cl,[Na+].[OH-],test
US20030232863A1,COC(=O)[C@H](CC(C)C)NC(c1ccccc1)C(F)(F)F>>CC(C)C[C@H](NC(c1ccccc1)C(F)(F)F)C(=O)O,,C1CCOC1,CO,[Li+].[OH-],,test
US20100113528A1,CC(C)OC(=O)c1ccc(OC(C)C)c(C(F)(F)F)c1>>CC(C)Oc1ccc(C(=O)O)cc1C(F)(F)F,,CCO,,[Na+].[OH-],,test
US20110021522A1,CC1(C)OC(=O)CC(=O)O1.O=Cc1cc(I)ccc1O>>O=C(O)c1cc2cc(I)ccc2oc1=O,,O,,,,test
US20010027196A1,CS(=O)c1nc(N)nc(-c2ccco2)c1Br.OCc1ccccn1>>Nc1nc(OCc2ccccn2)c(Br)c(-c2ccco2)n1,,C1COCCO1,,C1CCC2=NCCCN2CC1,,test
US20070049586A1,COc1c(F)ccc(C(=O)O)c1F.O=S(Cl)Cl>>COc1c(F)ccc(C(=O)Cl)c1F,,CCOC(C)=O,,,,test
US20100273764A1,C1CCNCC1.COc1ccc(Nc2nc(Cl)ncc2I)cn1>>COc1ccc(Nc2nc(N3CCCCC3)ncc2I)cn1,,O,,CCO,,test
US20120295884A1,CC(C)(C)OC(=O)NCc1cc(C(=O)O)cc(Cl)c1F.CN(C)CCN>>CN(C)CCNC(=O)c1cc(Cl)c(F)c(CNC(=O)OC(C)(C)C)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100137282A1,CC(Br)Br.CC(C)(C)C(=O)Nc1cccc(Cl)n1>>CC(C)(C)C(=O)Nc1nc(Cl)ccc1Br,,C1CCOC1,,O,[Li]CCCC,test
US04326087,Br.Fc1ccc(COc2ccccc2)cc1Oc1ccccc1>>Fc1ccc(CBr)cc1Oc1ccccc1,,O,,CC(=O)O,,test
US20030092749A1,CNOC.Nc1cc(C(=O)O)ccc1Nc1ccccc1.O=C(O)c1ccc(Nc2ccccc2)c([N+](=O)[O-])c1>>CON(C)C(=O)c1ccc2c(c1)[nH]c(=O)n2-c1ccccc1,,C1CCOC1,,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US20040152702A1,COc1ccc(-c2ccccc2)c2oc(N)nc12.O=C(Cl)c1ccc(F)cc1>>COc1ccc(-c2ccccc2)c2oc(NC(=O)c3ccc(F)cc3)nc12,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20110015175A1,Fc1ccc(C(CCCCCl)c2n[nH]c(Nc3cc(F)c(-n4cnc(Cl)c4)c(F)c3)n2)cc1>>Fc1ccc(C2CCCCn3nc(Nc4cc(F)c(-n5cnc(Cl)c5)c(F)c4)nc32)cc1,,CN(C)C=O,,[I-].[K+],,test
US20140148468A1,CC(=O)SCCC(F)(F)c1ccc(F)cc1>>Fc1ccc(C(F)(F)CCS)cc1,,CCO,,[Na+].[OH-],,test
US20100056512A1,CN(C)c1cccc(N)c1.CNC(=O)c1c(C)oc2cc(N(C)c3ccnc(Cl)n3)ccc12>>CNC(=O)c1c(C)oc2cc(N(C)c3ccnc(Nc4cccc(N(C)C)c4)n3)ccc12,,CN(C)C=O,,,,test
US05025031,CNS(=O)(=O)Cl.COc1ccccc1OCC(O)CO>>CNS(=O)(=O)OCC(O)COc1ccccc1OC,,ClCCl,,O,c1ccncc1,test
US20160264544A1,CC(C)(C)OC(N)=O.COC(=O)c1cc(Br)co1>>COC(=O)c1cc(NC(=O)OC(C)(C)C)co1,[Cu]I,Cc1ccccc1,,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US04480101,COc1nc(N)nc(S)n1.FC(F)Cl>>COc1nc(N)nc(SC(F)F)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160095858A1,CC(C)(C)c1ccc(C(=O)NS(=O)(=O)c2cccc(F)n2)c(C2=CCCCC2)n1>>CC(C)(C)c1ccc(C(=O)NS(=O)(=O)c2cccc(F)n2)c(C2CCCCC2)n1,[Pd],CO,,,,test
US05015260,COc1cc(C)c(OS(C)(=O)=O)cc1[N+](=O)[O-]>>COc1cc(C)c(O)cc1[N+](=O)[O-],,CO,O,Cl,[Na+].[OH-],test
US20090312388A1,BrCc1ccccc1.CCOC(=O)c1c(C(=O)OCC)c(OCC)c2ccccc2c1O>>CCOC(=O)c1c(C(=O)OCC)c(OCc2ccccc2)c2ccccc2c1OCC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090275537A1,CC(=O)Cl.CN(C(=O)OC(C)(C)C)[C@H](CO[Si](C)(C)C(C)(C)C)CC(C)(C)CO>>CC(=O)OCC(C)(C)C[C@@H](CO[Si](C)(C)C(C)(C)C)N(C)C(=O)OC(C)(C)C,,C1CCOC1,,c1ccncc1,,test
US20140288123A1,COC(=O)c1ccc(C(C)O)cc1.Oc1ccccc1>>COC(=O)c1ccc(C(C)Oc2ccccc2)cc1,,C1CCOC1,O,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04268676,CC(=O)[O-].COC1=C(C)C(=O)C2=C(C1=O)[C@@H](COC(N)=O)[C@@]1(OC)[C@H]3N[C@H]3CN21.NCCCl>>COC12C(CO)C3=C(C(=O)C(C)=C(NCCCl)C3=O)N1CC1NC12.NC(=O)O,,CO,,Cl,,test
US04129653,CCOC(=O)CCN1Cn2cc(C(=O)OCC)cc2-c2ccccc21>>O=C(O)CCN1Cn2cc(C(=O)O)cc2-c2ccccc21,,CO,O,Cl,[K+].[OH-],test
US20050282862A1,CC(C)(C)OC(=O)N1CCC(C(=O)Nc2ccc(I)cc2C(=O)Nc2ccc(Cl)cn2)CC1.O=C(O)C(F)(F)F>>O=C(Nc1ccc(Cl)cn1)c1cc(I)ccc1NC(=O)C1CCNCC1.O=C(O)C(F)(F)F,,ClCCl,,COc1ccccc1,,test
US20110098297A1,CC(C)Oc1cc(O)ccc1[N+](=O)[O-].CS(=O)(=O)c1ccc(Br)nc1>>CC(C)Oc1cc(Oc2ccc(S(C)(=O)=O)cn2)ccc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100222325A1,Cc1cc(Br)cc(F)c1C(=O)O.O=C(n1ccnc1)n1ccnc1>>Cc1cc(Br)cc(F)c1C(N)=O,,C1CCOC1,,,,test
US20030153570A1,Clc1ccc(Cl)c(I)c1.Clc1nc(Cl)nc(Cl)n1>>Clc1ccc(Cl)c(-c2nc(Cl)nc(Cl)n2)c1,,C1CCOC1,CN(C)P(=O)(N(C)C)N(C)C,CCCCC,[Li]C(C)(C)C,test
US20140221345A1,ClC[C@H]1CO1.c1ccc2c(c1)CCNC2>>c1ccc2c(c1)CCN(C[C@@H]1CO1)C2,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20050288273A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCCC3=O)C(=O)O1.CS(=O)(=O)c1ccc(C=O)cc1>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCC(=Cc2ccc(S(C)(=O)=O)cc2)C3=O)C(=O)O1,,CC(=O)O,,C1CCNCC1,,test
US20140053905A1,CCCCCCCCCCCCOC(=O)C1(C(=O)OCCCCCCCCCCCC)c2ccsc2C(C(=O)OCCCCCCCCCCCC)(C(=O)OCCCCCCCCCCCC)c2ccsc21>>CCCCCCCCCCCCOC(=O)c1c2ccsc2c(C(=O)OCCCCCCCCCCCC)c2ccsc12,,CN(C)C=O,,,,test
US20160108027A1,CC1CNC(C)(CO)CO1.COc1cc(C(=O)O)cc2nc(NCc3cc(Cl)ccn3)oc12>>COc1cc(C(=O)N2CC(C)OCC2(C)CO)cc2nc(NCc3cc(Cl)ccn3)oc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110039847A1,Nc1ccccc1-c1nnc(-c2ccccc2)s1.O=C(Cl)c1cc(Cl)cc(-c2ccccc2)n1>>O=C(Nc1ccccc1-c1nnc(-c2ccccc2)s1)c1cc(Cl)cc(-c2ccccc2)n1,,ClCCl,,CCN(CC)CC,CO,test
US20040053908A1,COCCOc1cc2nccc(Oc3ccc(N)cc3)c2cc1C#N.O=C=Nc1ccc(F)cc1>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccc(F)cc4)cc3)c2cc1C#N,,CC#N,,Cc1ccccc1,,test
US05354866,C1CCOC1.ClC(Cl)Cl.O=C1N[C@@H](Cc2ccccc2)CO1.[Li]CCCC>>O=C(CC1CCC1)N1C(=O)OCC1Cc1ccccc1,,ClC(Cl)Cl,,,,test
US20090221551A1,ClCCCl.Nc1nc2c(Cl)nc3ccccc3c2n1CCCO>>Nc1nc2c(Cl)nc3ccccc3c2n1CCCCl,,ClCCCl,,O=S(Cl)Cl,,test
US20120088764A1,CCOC(=O)c1cnc(N(C)Cc2cc3nc(-c4cccc(OCCO[Si](C)(C)C(C)(C)C)c4)nc(N4CCOCC4)c3s2)nc1>>CCOC(=O)c1cnc(N(C)Cc2cc3nc(-c4cccc(OCCO)c4)nc(N4CCOCC4)c3s2)nc1,,CCOC(C)=O,,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20090170861A1,CCOP(=O)(Cc1ccc([N+](=O)[O-])cc1)OCC.O=C(Cl)C(=O)Cl>>CCOP(=O)(Cl)Cc1ccc([N+](=O)[O-])cc1,,ClC(Cl)Cl,ClCCl,,,test
US20050250810A1,COC(=O)OC.Nc1ncc(Br)cc1CO>>O=C1Nc2ncc(Br)cc2CO1,,CO,,C[O-].[Na+],,test
US05929074,CCC(Cl)Br.COc1ccc(CNC(=O)OCc2ccccc2)cc1O>>COc1ccc(CNC(=O)OCc2ccccc2)cc1OCCCCl,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040186290A1,CS(=O)(=O)Cl.Nc1ccc(/C(=C\C2CCCC2)C(=O)Nc2ncc(Cl)s2)cn1>>CS(=O)(=O)Nc1ccc(/C(=C\C2CCCC2)C(=O)Nc2ncc(Cl)s2)cn1,,CCOCC,ClCCl,c1ccncc1,,test
US20060217382A1,COc1ccc(Nc2ncc(C(C)NC(=O)c3ccccc3F)nn2)cc1>>COc1ccc(Nc2ncc3c(C)nc(-c4ccccc4F)n3n2)cc1,,ClCCCl,,O=P(Cl)(Cl)Cl,,test
US05604229,CCCCCCCCCCCCCCCCCCCCCCC(COC(C)=O)(COC(C)=O)NC(C)=O.Cl>>CCCCCCCCCCCCCCCCCCCCCCC(N)(CO)CO.Cl,,CO,,[Na+].[OH-],,test
US20110053940A1,COC(=O)CCc1cc(CN(C(=O)OC(C)(C)C)C2CC2)c2ncccc2c1>>CC(C)(C)OC(=O)N(Cc1cc(CCCO)cc2cccnc12)C1CC1,,C1CCOC1,CCOCC,[BH4-].[Li+],,test
US20150018547A1,COC(=O)CC(=O)CCl.COc1cc(Cl)cc(S)c1Cl>>COC(=O)CC(=O)CSc1cc(Cl)cc(OC)c1Cl,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20030176418A1,CCCCC1CCNCC1.O=c1ccc2ccccc2n1CCCCl>>CCCCC1CCN(CCCn2c(=O)ccc3ccccc32)CC1,,CCOC(C)=O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20090291978A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(OC1CCCC1)[C@@H](NCC1c2[nH]c3ccccc3c2CCN1C(=O)OCc1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N(CC1c2[nH]c3ccccc3c2CCN1C(=O)OCc1ccccc1)[C@H](C(=O)OC1CCCC1)c1ccccc1,,C1CCOC1,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20120028961A1,CC(C)(C)CCc1ccc(CNC(=O)OC(C)(C)C)cc1>>CC(C)(C)CCc1ccc(CN)cc1,,C1COCCO1,CO,Cl,,test
US20040192708A1,Cn1c(N)c(NC(=O)Cc2ccc(N)cc2)c(=O)n(C)c1=O>>Cn1c(=O)c2[nH]c(Cc3ccc(N)cc3)nc2n(C)c1=O,,CO,,Cl,[Na+].[OH-],test
US20080009488A1,CN=C=S.Nc1ccc(C2(O)c3ccccc3C(=O)N2Cc2ccccc2)cc1N>>CNc1nc2cc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)ccc2[nH]1,,C1CCOC1,,Cl,,test
US07919524B2,CC(C)C(NCCN)c1oc2cc(Cl)ccc2c(=O)c1Cc1ccccc1.Cc1ccc(C(=O)Cl)cc1>>Cc1ccc(C2=NCCN2C(c2oc3cc(Cl)ccc3c(=O)c2Cc2ccccc2)C(C)C)cc1,,CCOCC,ClCCl,CCN(CC)CC,,test
US20050245518A1,CNc1ccc([N+](=O)[O-])cc1N.COC(OC)OC.O=C(O)C(F)(F)F>>Cn1cnc2cc([N+](=O)[O-])ccc21.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20090286974A1,COC(=O)Cc1cccc(OCCNCCC2CCN(c3nc4ccc(Cl)cc4s3)C2)c1>>O=C(O)Cc1cccc(OCCNCCC2CCN(c3nc4ccc(Cl)cc4s3)C2)c1,,CO,,C1CCOC1,[Na+].[OH-],test
US20090312314A1,Cc1ccc(N(CCc2ccc(C(F)(F)F)nc2)C(=O)C(=O)c2ccc(F)cc2)cc1C>>Cc1ccc(N(CCc2ccc(C(F)(F)F)nc2)C(=O)[C@@H](O)c2ccc(F)cc2)cc1C,,CO,,[BH4-].[Na+],,test
US20040180939A1,CC(C)(C)OC(=O)N[C@H]1CCOc2ccc(I)cc21.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(C)(C)OC(=O)N[C@H]1CCOc2ccc(B3OC(C)(C)C(C)(C)O3)cc21,,CCOCC,CS(C)=O,ClCCl,CC(=O)[O-].[K+],test
US06239151B1,CC(=O)NCC(=O)O.CC(C)CNNC(=O)[C@H](CC(C)C)[C@H](C/C=C/c1ccccc1)C(=O)NOC1CCCCO1>>CC(=O)NCC(=O)N(CC(C)C)NC(=O)[C@H](CC(C)C)[C@H](C/C=C/c1ccccc1)C(=O)NOC1CCCCO1,,CN(C)C=O,,CCN=C=NCCCN(C)C,Cl,test
US20050131052A1,CC(=O)OCC(=O)N(CC(=O)O)[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1>>O=C(O)CN(C(=O)CO)[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1,,C1CCOC1,,CO,O=C([O-])[O-].[K+].[K+],test
US20120202690A1,BrCc1ccccc1.Clc1nc(Cl)c2nc[nH]c2n1>>Clc1nc(Cl)c2ncn(Cc3ccccc3)c2n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130190290A1,CCN(CC)S(F)(F)F.Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cc(C(C)(C)O)cc(S(F)(F)(F)(F)F)c1>>Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cc(C(C)(C)F)cc(S(F)(F)(F)(F)F)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20070191309A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cc(N)c(C(=O)N2CCCC2CO)cc1OCc1ccccc1>>COc1cc(NC(=O)OC(C)(C)C)c(C(=O)N2CCCC2CO)cc1OCc1ccccc1,,C1CCOC1,,CCCCCC,CCOC(C)=O,test
US20040110802A1,N#CC(=O)OCc1ccccc1.c1ccc2ocnc2c1>>O=C(OCc1ccccc1)c1nc2ccccc2o1,,C1CCOC1,,[Li]CCCC,O=C([O-])O.[Na+],test
US04006009,C=CC(=O)Cl.CN1CCC(O)N(c2nnc(C(C)(C)C)s2)C1=O>>C=CC(=O)OC1CCN(C)C(=O)N1c1nnc(C(C)(C)C)s1,,c1ccccc1,,CCN(CC)CC,,test
US20060257987A1,CCOC(=O)C1CC1c1ccc(OCc2ccccc2)cc1C>>CCOC(=O)C1CC1c1ccc(O)cc1C,[Pd],CCOC(C)=O,,,,test
US20150282482A1,CI.COC(=O)c1sc2ccc(C(F)(F)F)cc2c1N.COC(C)(C)C>>COC(=O)c1sc2ccc(C(F)(F)F)cc2c1N(C)C,,COC(C)(C)C,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20120142928A1,CCOC(=O)N1CCC(N)CC1.O=[N+]([O-])c1ccc(Cl)nc1Cl>>CCOC(=O)N1CCC(Nc2nc(Cl)ccc2[N+](=O)[O-])CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04959373,CC(=O)Nc1ccc(C(=O)N2CC3CC(CN(Cc4ccccc4)C3)C2)cc1>>CC(=O)Nc1ccc(C(=O)N2CC3CNCC(C3)C2)cc1,[Pd],CO,,[H][H],,test
US20080269284A1,CC[C@@H]1C[C@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(CC(=O)OC)n2)c2cc(C(F)(F)F)ccc2N1C(=O)OC(C)C>>CC[C@@H]1C[C@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(CC(=O)O)n2)c2cc(C(F)(F)F)ccc2N1C(=O)OC(C)C,,CO,,Cl,[Na+].[OH-],test
US20140296208A1,COc1cc(O)cc([N+](=O)[O-])c1.OCCOCCOCCN1CCOCC1>>COc1cc(OCCOCCOCCN2CCOCC2)cc([N+](=O)[O-])c1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080051404A1,CO[C@H]1Cc2ccccc2[C@H]1N.Clc1nc(Cl)nc(Cl)n1>>CO[C@H]1Cc2ccccc2[C@H]1Nc1nc(Cl)nc(Cl)n1,,C1CCOC1,,CCN(C(C)C)C(C)C,O,test
US05530119,CC(C)(C)OC(=O)ON=C(C#N)c1ccccc1.NCCN1CCNCC1>>CC(C)(C)OC(=O)NCCN1CCNCC1,,C1COCCO1,O,,,test
US05589500,CCC(C(=O)O)c1ccccc1.ClCCCOc1ccccc1>>CCC(C(=O)c1ccc(OCCCCl)cc1)c1ccccc1,,O=C([O-])O,[Na+],O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US20110190283A1,CNCc1cc(Br)cnc1N.COC(=O)OC>>CN1Cc2cc(Br)cnc2NC1=O,,CO,O,C[O-].[Na+],,test
US05294631,Nc1ccc(Cl)c(C(=O)O)c1NCc1ccc(C(=O)O)cc1.O=CO>>O=C(O)c1ccc(Cn2cnc3ccc(Cl)c(C(=O)O)c32)cc1,,O,,,,test
US04372953,COC(=O)CCCn1nnnc1C>>Cc1nnnn1CCCC(=O)O,,Cl,,,,test
US20150322024A1,CC(C)c1nccn1CCN1C(=O)c2ccccc2C1=O>>CC(C)c1nccn1CCN,,CCO,,NN,O,test
US07928107B2,COc1cccc(Cl)c1C(=O)Cl.NC(=O)c1ccccc1N>>COc1cccc(Cl)c1C(=O)Nc1ccccc1C(N)=O,,c1ccncc1,,,,test
US20080139631A1,CCCc1cc2c(C(F)(F)F)c(C#N)ccc2[nH]1.CSc1ncccc1-c1nc(CCl)no1>>CCCc1cc2c(C(F)(F)F)c(C#N)ccc2n1Cc1noc(-c2cccnc2SC)n1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100099695A1,COC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C(C)(C)C)NC(=O)OCCCCCC=Cc1ccccc1C#CCO2>>COC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C(C)(C)C)NC(=O)OCCCCCCCc1ccccc1CCCO2,[Pd],CCOC(C)=O,,,,test
US20150141406A1,CCC(Br)CC.NC(=O)c1cc(-c2n[nH]c3cc[nH]c(=O)c23)cs1>>CCC(CC)n1nc(-c2csc(C(N)=O)c2)c2c(=O)[nH]ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20100009991A1,CCOC(=O)CCc1cccc(CCC(=O)O)c1>>CCOC(=O)CCc1cccc(CCCO)c1,,C1CCOC1,,,,test
US20150203511A1,Cc1c(F)ccc(-n2nnn(C)c2=O)c1CBr.Cc1cc(-c2ccn(C)n2)c(C)cc1O>>Cc1cc(-c2ccn(C)n2)c(C)cc1OCc1c(-n2nnn(C)c2=O)ccc(F)c1C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130330327A1,COc1c(OCC2(C)CO2)ccc2c1N=C(N)N1CCN=C21.C[C@H]1CNC[C@@H](C)O1>>COc1c(OC[C@](C)(O)CN2C[C@H](C)O[C@H](C)C2)ccc2c1N=C(N)N1CCN=C21,,CN(C)C=O,,,,test
US20050065118A1,Nc1cccc(SCc2ccc(-c3ccccc3)cc2)c1.S=C(Cl)Cl>>[N-]=C=S.c1ccc(SCc2ccc(-c3ccccc3)cc2)cc1,,CCCCCC,CCOC(C)=O,,,test
US20130018049A1,COC(=O)C(O)c1c(C)nc2c(ccn2Cc2ccc(F)c(F)c2)c1I>>COC(=O)C(=O)c1c(C)nc2c(ccn2Cc2ccc(F)c(F)c2)c1I,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20080146612A1,CC1(C#N)CCCCCC1>>CC1(CN)CCCCCC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130178459A1,COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc([C@@H](C)CNC(=O)OC(C)(C)C)cc1>>COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc([C@@H](C)CN)cc1,,O=C(O)C(F)(F)F,,,,test
US05082976,CN(C)C=Cc1ccccc1[N+](=O)[O-].O=O>>O=Cc1ccccc1[N+](=O)[O-],Cl[Cu],CN(C)C=O,,,,test
US20100216746A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nc(Cl)c(C(=O)O)[nH]1.N#Cc1cc(Oc2c(Cl)ccc(CN)c2F)cc(C2CC2)c1>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nc(Cl)c(C(=O)NCc2ccc(Cl)c(Oc3cc(C#N)cc(C4CC4)c3)c2F)[nH]1,,CCOC(C)=O,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
US04029491,Cc1ccc2sc(N)nc2c1.O=C(Cl)Cl>>Cc1ccc2sc(N=C=O)nc2c1,,CCOC(C)=O,,,,test
US20160009709A1,COC(=O)c1cc2cc([N+](=O)[O-])cnc2[nH]1>>O=C(O)c1cc2cc([N+](=O)[O-])cnc2[nH]1,,CO,O,Cl,[K+].[OH-],test
US05817690,O=C1Cc2c(cccc2OCCNCc2ccccc2)N1>>NCCOc1cccc2c1CC(=O)N2,[Pd],CCO,,,,test
US08012901B1,CC(C)[Si](Cl)(C(C)C)C(C)C.O=C(CSc1cccc(O)c1)c1ccc(F)cc1F>>CC(C)[Si](Oc1cccc(SCC(=O)c2ccc(F)cc2F)c1)(C(C)C)C(C)C,,ClCCl,,c1c[nH]cn1,,test
US04804398,CCOC=C(C(=O)OCC)C(=O)OCC.NNc1c(Cl)cc(C(F)(F)F)cc1Cl>>CCOC(=O)C(=CNNc1c(Cl)cc(C(F)(F)F)cc1Cl)C(=O)OCC,,CCO,,,,test
US20130065880A1,Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)N5CCN(C(=O)OC(C)(C)C)CC5)c[nH]4)c3)cc2F)c1>>Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)N5CCNCC5)c[nH]4)c3)cc2F)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130203991A1,CCOC(=O)CN1CCN(S(=O)(=O)Nc2cc(OC)nc(S(=O)(=O)Cc3cccc(F)c3F)n2)CC1>>COc1cc(NS(=O)(=O)N2CCN(CC(=O)O)CC2)nc(S(=O)(=O)Cc2cccc(F)c2F)n1,,CO,,[Na+].[OH-],,test
US20060025414A1,CN=C(SC)N1CCOCC1c1cc(-c2cccc(Cl)c2)on1.NNC(=O)c1ccncc1>>Cn1c(-c2ccncc2)nnc1N1CCOCC1c1cc(-c2cccc(Cl)c2)on1,,CCO,ClCCl,,,test
US03932452,N#Cc1ccc(CBr)cc1.O=C1NCCN1>>N#Cc1ccc(CN2CCNC2=O)cc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070299068A1,CCOc1ccc2cc(-c3ccc([N+](=O)[O-])cc3)n(CC3CC3)c2c1.O=C1CCC(=O)N1I>>CCOc1ccc2c(I)c(-c3ccc([N+](=O)[O-])cc3)n(CC3CC3)c2c1,,CN(C)C=O,O,,,test
US20080176926A1,CC1(C)CCC(=O)CC1.CCOC(C)=O>>CC(=O)C1CC(C)(C)CCC1=O,,Cc1ccccc1,,[H-].[Na+],,test
US05593993,Nc1ccccn1.S=C(n1ccnc1)n1ccnc1>>S=C(Nc1ccccn1)n1ccnc1,,CC#N,,,,test
US20090318475A1,COC(=O)CCCCCNc1ncnc2oc(Br)c(-c3ccc(OC)cc3)c12.OB(O)c1ccccc1F>>COC(=O)CCCCCNc1ncnc2oc(-c3ccccc3F)c(-c3ccc(OC)cc3)c12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CS(C)=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20150266862A1,COC(=O)C1CCNC1.O=Cc1cccc(S(=O)(=O)N2CCCC2)c1>>COC(=O)C1CCN(Cc2cccc(S(=O)(=O)N3CCCC3)c2)C1,,CCOC(C)=O,ClCCCl,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140171420A1,CC(C)c1c(N2CCC(n3nc(C4=NCCN4)c4cccnc43)C2=O)cnn1-c1ccc(F)cc1>>CC(C)c1c(N2CCC(n3nc(-c4ncc[nH]4)c4cccnc43)C2=O)cnn1-c1ccc(F)cc1,,CS(C)=O,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20090088430A1,CC(C)(C)OC(=O)N1CCC(N2CCC(Cc3c(Cl)cc(OS(=O)(=O)C(F)(F)F)cc3Cl)C2=O)CC1.COC(=O)c1ccc(B(O)O)cc1>>COC(=O)c1ccc(-c2cc(Cl)c(C[C@@H]3CCN(C4CCN(C(=O)OC(C)(C)C)CC4)C3=O)c(Cl)c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20140364414A1,CN(/N=C/c1ccc(Br)cc1)C(N)=O>>Cn1nc(-c2ccc(Br)cc2)[nH]c1=O,,CC(=O)O,,BrBr,,test
US05013829,CN(C)C=O.Nc1nc(I)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>N#Cc1nc(N)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20070072866A1,COc1cc(Br)cc(C=O)c1O.C[Si](C)(C)CCOCCl>>COc1cc(Br)cc(C=O)c1OCOCC[Si](C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070191340A1,CCBr.Cc1ccc(Cl)c(-c2ccc(CN3CCN[C@@H](Cc4ccccc4)C3)cc2)c1>>CCN1CCN(Cc2ccc(-c3cc(C)ccc3Cl)cc2)C[C@@H]1Cc1ccccc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090088463A1,Nc1cc(Cl)c(Cl)cc1Cl.O=c1c2ccnn2c(=O)c2ccnn12>>O=C(Nc1cc(Cl)c(Cl)cc1Cl)c1cc[nH]n1,,CN(C)C=O,c1ccncc1,,,test
US04116670,CCO.CCOC(CN(C(=O)CCl)C(C)C)OCC.Cc1ccccc1S(=O)(=O)O>>CC(C)N(CC1OCC(C)(C)CO1)C(=O)CCl,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US05846990,CNCC(C)C.Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(-c3ncco3)cc2C=O)c1C>>Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(-c3ncco3)cc2CN(C)CC(C)C)c1C,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05064953,CCOC(=O)CC(C)=O.Nc1n[nH]c(S)n1>>Cc1cc(O)n2nc(S)nc2n1,,CCO,,C1CCNCC1,,test
US05616586,CN(C)C=O.COC(=O)CC1CCc2cc(Br)cc3[nH]c(=O)c(=O)n1c23>>CONC(=O)CC1CCc2cccc3[nH]c(=O)c(=O)n1c23,[Pd],C1CCOC1,,CC(=O)O,[H][H],test
US20130005574A1,BrCc1ccccc1.COc1c(C(=O)O)nc(-c2ccc(Cl)c(OC)c2F)c(F)c1N>>COc1c(C(=O)OCc2ccccc2)nc(-c2ccc(Cl)c(OC)c2F)c(F)c1N,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US06265421B1,CCOC(=O)C1C(=O)CCCC1c1ccccc1.Oc1cc(O)cc(O)c1>>O=c1oc2cc(O)cc(O)c2c2c1C(c1ccccc1)CCC2,,CCO,,Cl,,test
US20050261310A1,OC1CCc2cc(-c3nccs3)ccc21>>C1=Cc2ccc(-c3nccs3)cc2C1,,C1CCOC1,O,Cl,,test
US20030181494A1,O=C1NC(=O)C(=Cc2ccc(O)cc2)S1>>O=C1NC(=O)C(Cc2ccc(O)cc2)S1,[Pd],CC(=O)O,,O=C[O-].[NH4+],,test
US04364875,N.O=[N+]([O-])c1ccc(Oc2ccccc2)c(Cl)c1Oc1ccccc1>>Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl,,Cc1ccccc1,,,,test
US20100035987A1,C=CCI.CC(C)(C)OC(=O)NC1CC=CCC1>>C=CCN(C(=O)OC(C)(C)C)C1CC=CCC1,,C1CCCCC1,CCOC(C)=O,,,test
US20130324506A1,Cc1c(-c2ccc(C(=O)N3CCC(=O)CC3)cc2)nc2n1CCc1ccccc1C2OC1CCN(C)CC1>>Cc1c(-c2ccc(C(=O)N3CCC(O)CC3)cc2)nc2n1CCc1ccccc1C2OC1CCN(C)CC1,,CO,,O,[BH4-].[Na+],test
US20140179667A1,CC(=O)Oc1nccc2c(Br)cc(OC(C)C)c(C)c12>>Cc1c(OC(C)C)cc(Br)c2cc[nH]c(=O)c12,,CO,,[Na+].[OH-],,test
US20060270637A1,COCCC(=O)O.O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(-c2ccc(C3=NO[C@H](CO)C3)nc2)c(F)c1>>COCCC(=O)OC[C@@H]1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,Cl,test
US05965740,CC(=NN)c1ccc(C(F)(F)F)cc1.COC(C1=CN(C)CS1)c1ccccc1C=O>>COC(C1=CN(C)CS1)c1ccccc1C=NN=C(C)c1ccc(C(F)(F)F)cc1,,CO,,,,test
US20080032971A1,COC(OC)c1ccnc(N)n1>>Nc1nccc(C=O)n1,,CCOC(C)=O,,Cl,O=C([O-])O.[Na+],test
US20110021493A1,Clc1ccc(Nc2ncnc3sc4c(c23)CCNC4)cc1Cl.O=C(O)/C=C/CBr.O=S(Cl)Cl>>O=C(/C=C/CCl)N1CCc2c(sc3ncnc(Nc4ccc(Cl)c(Cl)c4)c23)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05447819,CC(C)(C)c1ccc(O)c([N+](=O)[O-])c1>>CC(C)(C)c1ccc(O)c(N)c1,[Pd],CCOC(C)=O,,[H][H],,test
US20040176434A1,CC(=O)OC(C)=O.O=C1CC=c2cc3ccc4c(c3cc2C1)C=NN=4>>CC(=O)n1cc2c(ccc3cc4c(cc32)CC(=O)C=C4)n1,,CC(=O)O,,,,test
US05364871,BrBr.COC(=O)c1cncc(C(C)=O)c1>>Br.COC(=O)c1cncc(C(=O)CBr)c1,,C1COCCO1,,,,test
US05006534,CCCCC(OC(C)=O)c1cccc(CBr)c1.Oc1cccc2cccnc12>>CCCCC(OC(C)=O)c1cccc(COc2cccc3cccnc23)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120316161A1,CCCC(C(=O)OC)c1c(C)nc2c(nc(C)n2C)c1-c1ccc(C)cc1>>CCCC(C(=O)O)c1c(C)nc2c(nc(C)n2C)c1-c1ccc(C)cc1,,CCO,CO,[Na+].[OH-],,test
US05656573,CSSC.Cc1cc(Cl)ccc1N>>CSc1ccc(Cl)cc1C,,ClC(Cl)Cl,,CC(C)(C)ON=O,,test
US20050267101A1,CCCC(CC(=O)n1c2ccccc2c2ccccc21)C(=O)NC(CC(=O)OC(C)(C)C)C(O)CF>>CCCC(CC(=O)n1c2ccccc2c2ccccc21)C(=O)NC(CC(=O)OC(C)(C)C)C(=O)CF,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05840917,CCOC(=O)c1coc(Cl)c1>>O=C(O)c1coc(Cl)c1,,CCO,,[Na+].[OH-],,test
US05254685,C1CCNC1.CC1Cc2c(F)c(F)cc3c(=O)c(C(=O)O)cn(c23)N1C>>CC1Cc2c(N3CCCC3)c(F)cc3c(=O)c(C(=O)O)cn(c23)N1C,,CC#N,,,,test
US20060079556A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1CCC(CNCc2ccc(Cl)cc2)CC1>>CC(=O)N(Cc1ccc(Cl)cc1)CC1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,CCCCCC,CCN(CC)CC,CCOC(C)=O,test
US20130317023A1,Cc1nc(C)c(S(=O)(=O)Cl)s1.Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F>>Cc1nc(C)c(S(=O)(=O)Nc2ccc(F)c(Nc3ncccc3-c3ncnc4c3ncn4C3CCCCO3)c2F)s1,,ClCCl,,c1ccncc1,,test
US04975449,Nc1ccc(Cl)cc1S.S=C=S>>Sc1nc2ccc(Cl)cc2s1,,[Na+],[OH-],CC(=O)O,,test
US20050107364A1,CC1(CC=C2CCCCC2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21>>CC1(CCC2CCCCC2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21,[Pd],C1CCOC1,CO,[H][H],,test
US20090131336A1,[N-]=[N+]=NCc1cc(-c2ccco2)on1>>NCc1cc(-c2ccco2)on1,[Pd],CO,,,,test
US20110281884A1,CC(=O)OC(C)=O.COC(=O)c1cc(Cl)c(CN)nc1-c1cccc(F)c1>>COC(=O)c1cc(Cl)c(CNC(C)=O)nc1-c1cccc(F)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20060155136A1,C[C@@H](O)[C@@](O)(CCl)c1ccc(F)cc1F>>C[C@@H](O)[C@]1(c2ccc(F)cc2F)CO1,,CO,,O,C[O-].[Na+],test
US20160024110A1,CCOC(=O)C(=O)c1cc(Oc2ccccc2OC)c(Cl)cc1F.ClC(Cl)(Cl)Cl>>CCOC(=O)C(=C(Cl)Cl)c1cc(Oc2ccccc2OC)c(Cl)cc1F,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20010027196A1,CC#N.COC(=O)c1ccc(C)o1>>Cc1ccc(C(=O)CC#N)o1,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20090099173A1,C[C@@H]1CN(C(=O)c2ccccc2)CCN1c1nnc(Cl)c2cccnc12.N#Cc1ccc(B(O)O)cc1>>C[C@@H]1CN(C(=O)c2ccccc2)CCN1c1nnc(-c2ccc(C#N)cc2)c2cccnc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US20100298336A1,CCc1cncc(CBr)c1.Cc1cc(O)nc(S)n1>>CCc1cncc(CSc2nc(C)cc(O)n2)c1,,CCO,,CCN(CC)CC,CCOCC,test
US20140005146A1,C[C@@H](Nc1c(C(N)=O)cnn2cc(-c3cccc(CN)c3)cc12)C(C)(C)F.O=C(O)C1CC1>>C[C@@H](Nc1c(C(N)=O)cnn2cc(-c3cccc(CNC(=O)C4CC4)c3)cc12)C(C)(C)F,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US05422358,Clc1ccc(CCBr)cc1Cl.N#CC(c1ccccc1)(c1ccccc1)[C@H]1CCCNC1>>N#CC(c1ccccc1)(c1ccccc1)[C@H]1CCCN(CCc2ccc(Cl)c(Cl)c2)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070003539A1,CC(=O)OC(C)=O.N#Cc1cc(N)cc(N)c1>>CC(=O)Nc1cc(C#N)cc(NC(C)=O)c1,,ClCCl,,CCOC(C)=O,c1ccncc1,test
US20080242695A1,CCC(CC)Nc1cc(Cl)cnc1N.O=C(n1ccnc1)n1ccnc1>>CCC(CC)n1c(O)nc2ncc(Cl)cc21,,C1CCOC1,,,,test
US20100048568A1,C#CC1CC1.Nc1ccc(F)cc1I>>Fc1ccc(NC#CC2CC2)cc1,[Cu]I,C1CCOC1,,CCN(CC)CC,,test
US20120196861A1,CN(C)C(OC(C)(C)C)N(C)C.COC(=O)c1c(-c2c(F)cccc2Cl)noc1C>>COC(=O)c1c(-c2c(F)cccc2Cl)noc1C=CN(C)C,,Cc1ccccc1,,,,test
US20130102009A1,O=[N+]([O-])c1ccccc1-c1nc2cc(CN3CC[C@@H](F)C3)cnc2s1>>Nc1ccccc1-c1nc2cc(CN3CC[C@@H](F)C3)cnc2s1,[Fe],,,,,test
US20030153604A1,CC(C)(C)OC(=O)N1CCC(O)CC1.CCOC(=O)/N=N/C(=O)OCC.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>COC(=O)c1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1,,C1CCOC1,,,,test
US04920116,CCNCC.COc1cc(C(=O)CBr)cc(OC)c1OC>>CCN(CC)CC(=O)c1cc(OC)c(OC)c(OC)c1,,CCO,,,,test
US20080188467A1,COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(OCc4ccccc4)c(C)c3)cc2n1>>COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(O)c(C)c3)cc2n1,[Pd],CN(C)C=O,CO,,,test
US20120022080A1,Cc1ccc(-c2ccc(F)cc2)cc1N.O=C(CCl)Nc1ccc(Cl)cc1C(=O)O>>Cc1ccc(-c2ccc(F)cc2)cc1NCC(=O)Nc1ccc(Cl)cc1C(=O)O,,CCOC(C)=O,CN(C)C=O,[I-].[Na+],,test
US20090209585A1,CCOC(=O)C1=CCCCC1S(=O)(=O)N(C(=O)CCC(=O)OCC(Cl)(Cl)Cl)c1ccc(F)cc1Cl>>CCOC(=O)C1=CCCCC1S(=O)(=O)N(C(=O)CCC(=O)O)c1ccc(F)cc1Cl,[Zn],CN(C)C=O,,CC(=O)O,,test
US20130172618A1,COC(=O)c1ccc(I)c([N+](=O)[O-])c1.N>>NC(=O)c1ccc(I)c([N+](=O)[O-])c1,,CO,,,,test
US05109000,CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C(CC(C)C)C(CC(=O)NCC(=O)OC(C)(C)C)SC(C)=O>>CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C(CC(C)C)C(CC(=O)NCC(=O)O)SC(C)=O,,O,O=C(O)C(F)(F)F,,,test
US20100080770A1,C=CCC(C)(C)CCOC(=O)N[C@H](C(=O)O)C(C)(C)C.C=Cc1cc2cc([C@@]3(OC)CN[C@H](C(=O)OC)C3)ccc2cc1OC>>C=CCC(C)(C)CCOC(=O)N[C@H](C(=O)N1C[C@](OC)(c2ccc3cc(OC)c(C=C)cc3c2)C[C@H]1C(=O)OC)C(C)(C)C,,ClCCl,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20150197511A1,CCOC1(O[Si](C)(C)C)CC1.O=[N+]([O-])c1cc(C2=CCNCC2)cc(C(F)(F)F)c1>>O=[N+]([O-])c1cc(C2=CCN(C3CC3)CC2)cc(C(F)(F)F)c1,,CCO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20040235822A1,CCC=O.CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc([C@H](O)c4cccc[n+]4[O-])cc2)CCN3)cc1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc([C@H](O)c4cccc[n+]4[O-])cc2)CCN3CCC)cc1,,ClCCCl,,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090247507A1,Cc1cc(NC(=O)CN2CCN(C(=O)OC(C)(C)C)CC2)on1.Nc1ncc(Cl)c(Cl)c1[N+](=O)[O-]>>Cc1cc(NC(=O)CN2CCN(c3c(Cl)cnc(N)c3[N+](=O)[O-])CC2)on1,,CC(C)O,ClCCl,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US06841549B1,O=[N+]([O-])c1c(Cl)ncnc1Nc1ccnc(Cl)c1>>Nc1c(Cl)ncnc1Nc1ccnc(Cl)c1,[Zn],CC(=O)O,CCO,,,test
US04935431,CCCC(=O)c1cnc2ccsc2c1Cl.Cc1ccccc1N>>CCCC(=O)c1cnc2ccsc2c1Nc1ccccc1C,,C1COCCO1,ClCCl,,,test
US20080207654A1,CCCCc1nc(C)n(CC(=O)c2ccc(OC)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nc(C)n(CC(=O)c2ccc(OC)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20090093520A1,CC(=O)SCC(C(=O)O)C1CCNCC1.CC(C)(C)OC(=O)NCC(=O)ON1C(=O)CCC1=O>>CC(=O)SCC(C(=O)O)C1CCN(C(=O)CNC(=O)OC(C)(C)C)CC1,,C1COCCO1,,,,test
US20030036652A1,Nc1ccc(N2CCCCC2)nc1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ccc(N2CCCCC2)nc1)Oc1ccccc1,,ClCCl,,O,c1ccncc1,test
US05252560,CC(=O)Cl.CCOC(=O)c1ccc(N)cc1C(=O)OCC>>CCOC(=O)c1ccc(NC(C)=O)cc1C(=O)OCC,,ClCCl,,c1ccncc1,,test
US20070244173A1,COCCO[C@@H]1c2ccc3[nH]c(C)nc3c2O[C@H](c2ccccc2)[C@H]1OC(=O)C(C)(C)C>>COCCO[C@@H]1c2ccc3[nH]c(C)nc3c2O[C@H](c2ccccc2)[C@H]1O,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20040044211A1,CCOC(=O)c1cc(C2CN(C)Cc3c(Cl)cc(Cl)cc32)ccc1O.N=C(N)N>>CN1Cc2c(Cl)cc(Cl)cc2C(c2ccc(O)c(C(=O)NC(=N)N)c2)C1,,CN(C)C=O,,Cl,CC(C)(C)[O-].[K+],test
US05919777,COC(=O)[C@@H](Cc1ccccc1)NCCNC(=O)OC(C)(C)C.O=Cc1ccccc1>>O=C1NCCN(Cc2ccccc2)[C@@H]1Cc1ccccc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20090137609A1,CCC(CC)(c1ccc(CCC(O)C(C)(C)C)c(C)c1)c1ccc(-c2ccc(C(O)C(=O)OC)cc2)c(C)c1>>CCC(CC)(c1ccc(CCC(O)C(C)(C)C)c(C)c1)c1ccc(-c2ccc(C(O)C(=O)O)cc2)c(C)c1,,CO,,Cl,[Na+].[OH-],test
US04962115,CC1(C)OC(=O)CC(=O)O1.O=C(Cl)CCC(c1ccc(F)cc1)c1ccc(F)cc1>>CC(=O)CCC(c1ccc(F)cc1)c1ccc(F)cc1,,O,,ClCCl,c1ccncc1,test
US05686445,ClCl.O=c1[nH]c2ccccc2c(=O)c2ccccc12>>O=c1[nH]c2ccccc2c(=O)c2cc(Cl)ccc12,,CC(=O)O,,,,test
US20060040985A1,CN(CC1(O)CCN(CCc2ccc(C#N)cc2)CC1)c1ccc(C(=O)O)cc1.CS(=O)(=O)O>>CN(CC1(O)CCN(CCc2ccc(C#N)cc2)CC1)c1ccc(C(=O)O)cc1.CS(=O)(=O)O,,O,,,,test
US20140336166A1,BrBr.C[C@H]1COCCN1c1nc(N2CCOC[C@H]2C)c2nc[nH]c2n1>>C[C@H]1COCCN1c1nc(N2CCOC[C@H]2C)c2nc(Br)[nH]c2n1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20080027068A1,CCn1nc(C(C)=O)c(O)c1-c1ccc(C(C)(C)C)cc1.NNC(=S)Nc1ccc(C(=O)O)cc1>>CCn1nc(C(C)=NNC(=S)Nc2ccc(C(=O)O)cc2)c(O)c1-c1ccc(C(C)(C)C)cc1,Cl,O,,CN(C)C=O,,test
US20090036436A1,O=Cc1ccncc1.[C-]#[N+]CC(=O)N1CCN(C)CC1>>CN1CCN(C(=O)[C@@H]2N=CO[C@H]2c2ccncc2)CC1,,CO,,[K+].[OH-],,test
US20130172302A1,C1CCNCC1.COC(=O)C(Br)c1ccc(C)cc1>>COC(=O)C(c1ccc(C)cc1)N1CCCCC1,,CC#N,,,,test
US20020032340A1,CCC(C#CCO[C@H](C)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C)(CC)O[Si](CC)(CC)CC>>CCC(O)(C#CCO[C@H](C)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C)CC,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110212031A1,CN(C(=O)OC(C)(C)C)c1ccc(C(=O)O)cc1.Nc1ccc(F)nc1F>>CNc1ccc(-c2nc3ccc(F)nc3o2)cc1,,ClCCl,c1ccncc1,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140274696A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1nc(-c2ccc(Cl)c(F)c2)c(F)c(N)c1Cl>>COC(=O)c1nc(-c2ccc(Cl)c(F)c2)c(F)c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1Cl,CN(C)c1ccncc1,ClCCl,,,,test
US20100249119A1,CC(=O)OCC(=O)Cl.CC(C)(C#N)c1cccc(C(=O)Nc2cc(Oc3ccc4nc(N)sc4n3)c(Cl)cc2F)c1>>CC(C)(C#N)c1cccc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)CO)sc4n3)c(Cl)cc2F)c1,,CCOC(C)=O,c1ccncc1,O=C([O-])[O-].[Na+].[Na+],,test
US20130131018A1,CC(=O)OC(C)=O.COc1ccc2c(Cc3cc(OC)c(OC)c(OC)c3)cncc2c1.O=[N+]([O-])O>>COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)cncc2c1.O=[N+]([O-])O,,CC(=O)OC(C)=O,,,,test
US20140288063A1,COc1ccc(COc2nc(SC)ncc2C(=O)O)cc1Cl.NCc1ccccn1>>COc1ccc(COc2nc(SC)ncc2C(=O)NCc2ccccn2)cc1Cl,,C1CCOC1,O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020016368A1,CCOC(=O)C(=O)CBr.CS(=O)(=O)NCCCC(N)=S>>CCOC(=O)c1csc(CCCNS(C)(=O)=O)n1,,CCO,,,,test
US20050187228A1,NCCNc1nc(Cl)nc2c1ncn2C1CCCC1.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>O=S(=O)(NCCNc1nc(Cl)nc2c1ncn2C1CCCC1)c1ccc(C(F)(F)F)cc1,,O,,CCN(CC)CC,ClCCl,test
US20130267493A1,CC(C)(C)OC(=O)N1CCC(c2ccc(-c3cc4c(C(=O)O)c[nH]c4cc3Cl)cc2)C1>>O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(C4CCNC4)cc3)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060160864A1,CCCCOCCOc1ccc(-c2ccc(N3CCCC3)c(/C=C/C(=O)O)c2)cc1.CCCn1cncc1C[S@](=O)c1ccc(N)cc1>>CCCCOCCOc1ccc(-c2ccc(N3CCCC3)c(/C=C/C(=O)Nc3ccc([S@@](=O)Cc4cncn4CCC)cc3)c2)cc1,CN(C)C=O,C1CCOC1,O,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20080015227A1,CI.O=C(O)C1CCCCC1C(=O)c1ccc(Br)cc1>>COC(=O)C1CCCCC1C(=O)c1ccc(Br)cc1,,CN(C)C=O,O,Cl,O=C([O-])O.[Na+],test
US20090099187A1,COc1ccc(Cl)cc1N.COc1ccc(S(=O)(=O)Cl)c2c1C[C@@H](NC(=O)C(F)(F)F)CO2>>COc1ccc(Cl)cc1NS(=O)(=O)c1ccc(OC)c2c1OC[C@H](NC(=O)C(F)(F)F)C2,,ClC(Cl)Cl,,c1ccncc1,,test
US20070281990A1,COc1ccc2c(c1)C(CCCN(C)C)c1ccccc1CO2>>CN(C)CC/C=C1/c2ccccc2COc2ccc(O)cc21,,CC(=O)O,,I,,test
US20110015230A1,CCNc1cc(F)ccc1C(=O)N(C)OC.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCNc1cc(F)ccc1C=CC(=O)OC,,C1CCOC1,Cc1ccccc1,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06242601B1,COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(-c2ccnc(C#N)c2)nc1OC.ClCc1ccccc1>>COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(-c2ccnc(CN)c2)nc1OC.Cl,[Pd],CO,,,,test
US04433152,CC(=O)Nc1ccc(O)cc1.Cl.N=C(N)N1CCC(CCC(=O)O)CC1>>CC(=O)Nc1ccc(OC(=O)CCC2CCN(C(=N)N)CC2)cc1.Cl,,c1ccncc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20030207937A1,Brc1ccc2c(c1)CCCO2.C=C(OCC)[Sn](CCCC)(CCCC)CCCC>>CC(=O)c1ccc2c(c1)CCCO2,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,,,,test
US20130345194A1,COc1ccc(/C=N\S(=O)(=O)N2CCN(c3ncnc4[nH]ccc34)CC23CC3)cc1>>COc1ccc(CNS(=O)(=O)N2CCN(c3ncnc4[nH]ccc34)CC23CC3)cc1,,CO,,[BH4-].[Na+],,test
US20150225405A1,Cn1cc(-n2c3ccc(F)cc3c3c2cnn3C2CCCCO2)c(C(=O)O)n1>>Cn1cc(-n2c3ccc(F)cc3c3[nH]ncc32)c(CO)n1,,CCOCC,,C1CCOC1,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20110130438A1,O=C1CCC(=O)O1.O=[N+]([O-])c1cccc(COc2ccc(-c3ccc(F)cc3F)cc2)c1>>O=C(O)CCC(=O)Nc1cccc(COc2ccc(-c3ccc(F)cc3F)cc2)c1,[Pd],C1CCOC1,,,,test
US05155236,CC=C(OCC)OCC.COC(=O)C(=CNC(C)=O)C(C)=O>>CCOC1(OCC)OC(C)=C(C(=O)OC)[C@@H](NC(C)=O)[C@@H]1C,,Cc1ccccc1,,,,test
US20150225342A1,COc1ccc(N=C=O)cc1.OC1(c2ccccc2)CC2CNCC2C1>>COc1ccc(NC(=O)N2CC3CC(O)(c4ccccc4)CC3C2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05362725,CCOC(=O)Cl.CN1CCN2c3ccccc3Cc3ccccc3[C@H]2C1>>CCOC(=O)N1CCN2c3ccccc3Cc3ccccc3[C@H]2C1,,Cc1ccccc1,,,,test
US20080275085A1,CC1(C)OC(=O)NC1=O.ClCCCBr>>CC1(C)OC(=O)N(CCCCl)C1=O,,CN(C)C=O,,[H-].[Na+],,test
US04752645,C=CC[C@@H]1C(=O)N(CCN(C)C)c2cccc(C(F)(F)F)c2C[C@@H]1c1ccc(OC)cc1>>CCCC1C(=O)Nc2cccc(C(F)(F)F)c2CC1c1ccc(OC)cc1,[Pd],CCOC(C)=O,,,,test
US20160256577A1,CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4NC(=O)O[C@H](C)c4ccccc4Br)cc3)cc2)CC1.C[Sn](C)(C)[Sn](C)(C)C>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4NC(=O)O[C@H](C)c4ccccc4[Sn](C)(C)C)cc3)cc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20160016968A1,N#Cc1cc(OCC2CC2)c(C2CC2)cn1.NO>>NC(=NO)c1cc(OCC2CC2)c(C2CC2)cn1,,CCO,,CCN(CC)CC,Cl,test
US20090069370A1,COC(=O)c1ccc(CBr)cc1.O=C1c2ccc(O)cc2CCN1C1CCN(C2CCC2)CC1>>COC(=O)c1ccc(COc2ccc3c(c2)CCN(C2CCN(C4CCC4)CC2)C3=O)cc1,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05703017,COC(=O)C(O)C(C)(OCc1ccccc1)c1ccccc1.COc1cc(OC)nc(S(C)(=O)=O)n1>>COC(=O)C(Oc1nc(OC)cc(OC)n1)C(C)(OCc1ccccc1)c1ccccc1,,CC(=O)O,CN(C)C=O,O,[H-].[Na+],test
US20100041634A1,C1CC2CNCC12.O=[N+]([O-])c1ccc(Cl)nc1>>O=[N+]([O-])c1ccc(N2CC3CC3C2)nc1,,C1COCCO1,,CCN(CC)CC,,test
US20140315928A1,CCOC(=O)c1c(-c2ccc(C(=O)N(c3ncccc3Cl)[C@@H]3CCCN(C(=O)OC(C)(C)C)C3)cc2)cnn1C>>CCOC(=O)c1c(-c2ccc(C(=O)N(c3ncccc3Cl)[C@@H]3CCCNC3)cc2)cnn1C,,ClCCl,,Cl,,test
US20150099770A1,CCOC(=O)CBr.NCC(F)F>>CCOC(=O)CNCC(F)F,,CC#N,,CCN(C(C)C)C(C)C,[I-].[K+],test
US20080167339A1,CCCCCCCN=C=O.O=c1[nH]c2ncccc2o1>>CCCCC(CC)C(N)=O.O=c1[nH]c2ncccc2o1,,C1COCCO1,,,,test
US20050014789A1,CO.O=C(O)c1ccc2c(c1O)CCCC2>>COC(=O)c1ccc2c(c1O)CCCC2,,CO,Cc1ccccc1,C[Si](C)(C)C=[N+]=[N-],,test
US20120294835A1,Clc1cc(Cl)ncn1.NCCO.Nc1cccc(Br)c1>>OCCNc1cc(Nc2cccc(Br)c2)ncn1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20060211682A1,COC(=O)[C@@H](C)NCC(C)CNC(=O)OC(C)(C)C.O=C(OCc1ccccc1)ON1C(=O)CCC1=O>>COC(=O)[C@@H](C)N(CC(C)CNC(=O)OC(C)(C)C)C(=O)OCc1ccccc1,,ClCCl,,,,test
US04307116,CC(C)(C)OC(=O)NCCNC(=S)NN.CCOC(=O)C(=O)OCC>>CC(C)(C)OC(=O)NCCn1c(=S)[nH][nH]c(=O)c1=O,,CO,O,Cl,[Na],test
US06765008B1,CCC(=NO)c1nc(C)nc2c1c(C)c(C)n2-c1c(C)cc(C)cc1C>>CCC(N)c1nc(C)nc2c1c(C)c(C)n2-c1c(C)cc(C)cc1C,[Pd],CO,,,,test
US20080015199A1,COC(=O)N=C(SC)C(=Nc1ccc(-c2noc(C)n2)cc1)c1ccc(OCC#N)c(OC)c1.NNc1ncccn1>>COc1cc(C(Nc2ccc(-c3noc(C)n3)cc2)c2nn(-c3ncccn3)c(=O)[nH]2)ccc1OCC#N,,CN(C)C=O,,CCN(CC)CC,,test
US05639780,CC(=O)C=CC1(CC#N)CC1>>CC(=O)CCC1(CC#N)CC1,[Pd],CCOC(C)=O,,[H][H],,test
US20050256316A1,COc1c(Cl)cc(CC(N=C(c2ccccc2)c2ccccc2)C(=O)NCCCCc2ccccc2)c2cnn(S(=O)(=O)c3ccccc3)c12.Cl>>COc1c(Cl)cc(CC(N)C(=O)NCCCCc2ccccc2)c2cnn(S(=O)(=O)c3ccccc3)c12.Cl,,CCOCC,,,,test
US20160176861A1,CC(C)(O)c1onc(-c2c(Cl)cccc2Cl)c1CO.O=S(Cl)Cl>>CC(C)(O)c1onc(-c2c(Cl)cccc2Cl)c1CCl,,ClCCl,,,,test
US20140350036A1,Cc1c[nH]c(=O)[nH]c1=O.O=C(Cl)c1ccccc1>>Cc1c[nH]c(=O)n(C(=O)c2ccccc2)c1=O,,C1CCOC1,,c1ccncc1,,test
US06194461B1,COC(=O)c1ccc(F)cc1OC>>COc1cc(F)ccc1CO,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20110124662A1,COc1nc(C(Br)Br)c([N+](=O)[O-])cc1C>>COc1nc(C)c(N)cc1C,[Pd],CCO,,CCN(CC)CC,,test
US20130123235A1,CCNC/C=C\c1cc(F)ccc1S(=O)(=O)N(COCC[Si](C)(C)C)c1ccc2c(c1C(=O)OC)OCc1occc1-2>>CCNC/C=C\c1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1C(=O)OC)OCc1occc1-2,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20050137201A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=C(Cc1cccc(F)c1F)c1c[nH]c2ncc(Br)cc12>>CC1(C)OB(c2cnc3[nH]cc(C(=O)Cc4cccc(F)c4F)c3c2)OC1(C)C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,CC(=O)[O-].[K+],,test
US20090069297A1,COc1cnc2c(Oc3ccc(N)cc3)ccnc2c1.Clc1nnc(Cl)c2ccccc12>>COc1cnc2c(Oc3ccc(Nc4nnc(Cl)c5ccccc45)cc3)ccnc2c1,,CC(C)(C)O,,,,test
US20050009840A1,CCN(CC)CCN.Nc1ncc(-c2ccc(C(=O)O)cc2)cc1OCc1c(Cl)cccc1Cl>>CCN(CC)CCNC(=O)c1ccc(-c2cnc(N)c(OCc3c(Cl)cccc3Cl)c2)cc1,,CCOC(C)=O,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
US20140213586A1,COc1cc(N)cc(OC)c1.O=C(c1c[nH]c2ccc(CCCO)cc12)C(Br)c1ccc(F)cc1>>COc1cc(NC(C(=O)c2c[nH]c3ccc(CCCO)cc23)c2ccc(F)cc2)cc(OC)c1,,CC#N,,,,test
US20100292235A1,O=c1c2cccc([N+](=O)[O-])c2ccn1Cc1ccc(C(F)(F)F)nc1>>Nc1cccc2c(=O)n(Cc3ccc(C(F)(F)F)nc3)ccc12,[Pd],CO,,,,test
US04093736,COc1cc(Cl)ccc1C(=O)CCCCCBr>>COc1cc(Cl)ccc1C(O)CCCCCBr,,C1CCOC1,,B,Cl,test
US20090124596A1,CC(C)(C)OC(=O)N1CCN(CC(=O)O)CC1.N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccccc4)c3)c2=O)CC1>>CC(C)(C)OC(=O)N1CCN(CC(=O)N[C@@H]2CC[C@H](n3c(=O)c4cc(F)cnc4n(-c4cccc(-c5ccccc5)c4)c3=O)CC2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20080312234A1,CCCCNc1nc(C(F)(F)F)ccc1C#CC(=O)OC>>CCCCNc1nc(C(F)(F)F)ccc1C#CC(=O)O,,C1CCOC1,,Cl,[Li+].[OH-],test
US20160229865A1,C=CC(=O)Cl.Clc1nc(NCC2CNC2)c2occc2n1>>C=CC(=O)N1CC(CNc2nc(Cl)nc3ccoc23)C1,,ClCCl,,CCN(CC)CC,,test
US20080146606A1,CS(=O)(=O)OS(C)(=O)=O.O=S(=O)(c1ccc(-c2ccnc3c2cc(CO)n3S(=O)(=O)c2ccccc2)cc1)N1CCCC1>>CS(=O)(=O)OCc1cc2c(-c3ccc(S(=O)(=O)N4CCCC4)cc3)ccnc2n1S(=O)(=O)c1ccccc1,,ClCCl,,,,test
US05395846,O=S(Br)Br.OCc1ccc(-c2nc3ccccc3o2)cc1>>BrCc1ccc(-c2nc3ccccc3o2)cc1,,ClCCl,,Cc1cccc(C)n1,,test
US20070185140A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](Nc2nc(N3CCc4cc(N)ccc43)c3ncn(C(=O)OC(C)(C)C)c3n2)CC1.O=C=Nc1ccc(Cl)c(Cl)c1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](Nc2nc(N3CCc4cc(NC(=O)Nc5ccc(Cl)c(Cl)c5)ccc43)c3ncn(C(=O)OC(C)(C)C)c3n2)CC1,,O,,ClCCl,,test
US20120178770A1,Cc1csc(C(=O)Cl)c1.Cn1c(-c2ccnc(N)n2)cc2c1CCN(C(=O)OC(C)(C)C)C2=O>>Cc1csc(C(=O)Nc2nccc(-c3cc4c(n3C)CCN(C(=O)OC(C)(C)C)C4=O)n2)c1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20100048591A1,COc1ccc(COc2c(OC)cncc2OC)cc1.II>>COc1ccc(COc2c(OC)cnc(I)c2OC)cc1,,C1CCOC1,,[Li]C(C)(C)C,,test
US20100173880A1,O=C(O)[C@H](Nc1ccc(F)cc1)c1ccccc1.O[C@@H]1CN2CCC1CC2>>O=C(O[C@H]1CN2CCC1CC2)[C@H](Nc1ccc(F)cc1)c1ccccc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060135517A1,CC(C)(C)OC(=O)NCCCCCN.Cc1cccc(-c2nc3ccccn3c2-c2ccnc(S(C)(=O)=O)n2)n1>>Cc1cccc(-c2nc3ccccn3c2-c2ccnc(NCCCCCNC(=O)OC(C)(C)C)n2)n1,,CC#N,,,,test
US05292760,Cc1ccsc1C(Cc1ccccc1N)N(C)C=O>>Cc1ccsc1C(Cc1ccccc1N)N(C)C,,C1CCOC1,,B,,test
US20040116692A1,O=Cc1cccnc1.c1ccc(N2CCNCC2)cc1>>c1ccc(N2CCN(Cc3cccnc3)CC2)cc1,,C1CCOC1,,CC(=O)O,[BH4-].[Na+],test
US20020107278A1,CC(C)(C)OC(=O)N1CCc2c(n(CCO)c3ccccc23)CC1.Oc1ccc(Cl)cc1>>CC(C)(C)OC(=O)N1CCc2c(n(CCOc3ccc(Cl)cc3)c3ccccc23)CC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160145247A1,CC(C)(C)OC(=O)NCc1cc(F)cc(B2OC(C)(C)C(C)(C)O2)c1.COC(=O)Cc1ccccc1OCc1cccc(Br)c1>>NCc1cc(F)cc(-c2cccc(COc3ccccc3CC(=O)O)c2)c1,,CN(C)C=O,,,,test
US20080045530A1,COC(=O)[C@@H]1CN(Cc2ccccc2)C[C@H]1NC(=O)OC(C)(C)C>>COC(=O)[C@@H]1CNC[C@H]1NC(=O)OC(C)(C)C,[Pd],CO,,,,test
US04988828,C1CCNCC1.O=Cc1cccc(OCCCNC(=O)CS(=O)Cc2ccco2)c1>>O=C(CS(=O)Cc1ccco1)NCCCOc1cccc(CN2CCCCC2)c1,,CCO,,Cl,[BH4-].[Na+],test
US20100331283A1,CC(C)(C)OC(=O)N1CCc2nc(N3N=C(c4cc(F)ccc4F)SC3(CCO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)c3ccccc3)sc2C1>>OCCC1(c2ccccc2)SC(c2cc(F)ccc2F)=NN1c1nc2c(s1)CNCC2,,C1COCCO1,,Cl,O,test
US20150250896A1,COC(=O)CCS(=O)(=O)CCBr>>C=CS(=O)(=O)CCC(=O)O,,C1CCOC1,,Cl,[Na+].[OH-],test
US06107481,CC(C)(C)OC(=O)C1=C(C=Cc2ccc([N+](=O)[O-])cc2[N+](=O)[O-])CS[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N12>>O=C(Cc1ccccc1)N[C@@H]1C(=O)N2C(C(=O)O)=C(C=Cc3ccc([N+](=O)[O-])cc3[N+](=O)[O-])CS[C@H]12,Cl[Ti](Cl)(Cl)Cl,ClCCl,O,Cl,,test
US04062844,C1CCOC1.COc1cc2nc(N3CCN(C#N)CC3)nc(N)c2cc1OC.c1ccoc1>>COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)nc(N)c2cc1OC,,CCCCCC,,[Li]CCCC,,test
US20150094295A1,CC(C)(C=C(C#N)C(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4ccccc4)cc3F)c3c(N)ncnc32)C1)N1CC(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C1>>CC(C)(C=C(C#N)C(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4ccccc4)cc3F)c3c(N)ncnc32)C1)N1CC(O)C1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US03931239,CCCCC(=O)Cl.Cc1ccc2oc(C(=O)O)cc2c1C>>CCCCC(=O)c1cc2oc(C(=O)O)cc2c(C)c1C,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20030096836A1,C[Si](C)(C)CCOCCl.Cc1ccc(S(=O)(=O)c2[nH]cnc2-c2ccccn2)cc1>>Cc1ccc(S(=O)(=O)c2c(-c3ccccn3)ncn2COCC[Si](C)(C)C)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US06358985B1,COc1cccc(CCC(N=[N+]=[N-])c2ccccc2)c1>>COc1cccc(CCC(N)c2ccccc2)c1,[Pd],CCO,,,,test
US20140336185A1,COc1ccc(CC(=O)Nc2ccc(C(=O)N(CC(=O)OC(C)(C)C)Cc3ccc(C(=O)NNC(=O)c4ccc(-c5ccc(C)cc5)cc4)cc3)cc2)c(C(F)(F)F)c1>>COc1ccc(CC(=O)Nc2ccc(C(=O)N(CC(=O)O)Cc3ccc(-c4nnc(-c5ccc(-c6ccc(C)cc6)cc5)o4)cc3)cc2)c(C(F)(F)F)c1,,ClCCl,,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US20040157826A1,COC(=O)[C@@H]1c2[nH]ncc2[C@H]2CN1C(=O)N2OCc1ccccc1.N.O=C(Cl)OC(Cl)(Cl)Cl>>COC(=O)[C@@H]1c2nn(C(N)=O)cc2[C@H]2CN1C(=O)N2OCc1ccccc1,,ClCCl,ClCCl,,,test
US20130281366A1,CCOC(=O)COc1ccc(C(=O)CC)cc1.NO>>CCOC(=O)COc1ccc(C(CC)=NO)cc1,,CO,O,Cl,CC(=O)[O-].[Na+],test
US20110251225A1,CO.COC(=O)C1(CC=O)CCOCC1.Cc1cc(N2CC[C@H](N3CCC[C@@H]3C)C2)ccc1N.N>>CO.COC(=O)C1(CCNc2ccc(N3CC[C@H](N4CCC[C@@H]4C)C3)cc2C)CCOCC1.N,,ClCCCl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20040102433A1,C1CCOC1.C=CCOC(=O)C1=C(OP(Oc2ccccc2)Oc2ccccc2)[C@H](C)[C@@H]2[C@@H]([C@@H](C)O[Si](C)(C)C)C(=O)N12.CC#N.O=C([O-])N1CC=C(c2csc(S)n2)C[C@H]1CCl>>C=CCOC(=O)C1=C(Sc2nc(C3=CCN(C(=O)OCC=C)[C@H](CCl)C3)cs2)[C@H](C)[C@@H]2[C@@H]([C@@H](C)O[Si](C)(C)C)C(=O)N12,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20060257987A1,CC(=O)OC(C)=O.Cc1ccc(S(=O)(=O)OCCCC(C)O)cc1>>CC(=O)OC(C)CCCOS(=O)(=O)c1ccc(C)cc1,,ClCCl,,CCN(CC)CC,,test
US20070249670A1,CC(C)(C)OC(=O)NC1(C(=O)O)Cc2ccccc2C1.CO>>COC(=O)C1(NC(=O)OC(C)(C)C)Cc2ccccc2C1,,CO,,C[Si](C)(C)C=[N+]=[N-],,test
US20160221972A1,CC1=NCCOc2cc(Br)ccc21>>CC1NCCOc2cc(Br)ccc21,,CO,,CC(=O)[O-].[Na+],,test
US20120245345A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CC(=O)O)CC1.O=C1OC(=O)c2ccccc21>>O=C(O)C[C@@H]1CC[C@@H](N2C(=O)c3ccccc3C2=O)CC1,,ClCCl,,CO,O=C(O)C(F)(F)F,test
US20150065519A1,O=S(=O)(Nc1ccc(-c2csc(Br)n2)c(Cl)c1)C(F)(F)F.OB(O)c1ccnc(N2CCCCC2)c1>>O=S(=O)(Nc1ccc(-c2csc(-c3ccnc(N4CCCCC4)c3)n2)c(Cl)c1)C(F)(F)F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US08431695B2,CC(C)(C)OC(=O)N1CCCC(c2ccc3c(N)ncnn23)CC1.CC1(C)C(=O)N(Br)C(=O)N1Br>>CC(C)(C)OC(=O)N1CCCC(c2cc(Br)c3c(N)ncnn23)CC1,,C1CCOC1,,,,test
US20060173019A1,COCN(c1cc(Cl)cnc1C(=O)c1ccccc1N)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1.CS(=O)(=O)Cl>>COCN(c1cc(Cl)cnc1C(=O)c1ccccc1NS(C)(=O)=O)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1,,c1ccncc1,,Cl,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20120208797A1,N#Cc1ccc(F)cc1.OC1CCCNCC1>>N#Cc1ccc(N2CCCC(O)CC2)cc1,,CS(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20140187553A1,Cc1ccc(S(=O)(=O)n2cc(-c3cncc(C4CC4)n3)c3cc(-c4nnc(C5CC5)o4)ccc32)cc1>>c1cc2[nH]cc(-c3cncc(C4CC4)n3)c2cc1-c1nnc(C2CC2)o1,,C1COCCO1,,[Na+].[OH-],,test
US20040175741A1,CC(CO)c1cc(C2(c3ccccc3)OCCCO2)ccc1[N+](=O)[O-]>>CC(CO)c1cc(C(=O)c2ccccc2)ccc1[N+](=O)[O-],,CCO,O,Cl,,test
US20090270405A1,Nc1nc2ccccc2[nH]1.S=C(n1ccnc1)n1ccnc1>>S=C(Nc1nc2ccccc2[nH]1)n1ccnc1,,CC#N,,,,test
US05276025,CCOC(=O)c1cc(S(N)(=O)=O)sc1Cl.NCCS>>NS(=O)(=O)c1cc2c(s1)SCCNC2=O,,CCO,,Cl,[Na],test
US20100004208A1,C#CC.CN(C)C=O.COc1cc(I)cc(OC)c1OC.COc1ccc(I)c(NC(=O)C(F)(F)F)c1>>COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)c(C)[nH]c2c1,[Cu]I,CN(C)C=O,,CCN(C(C)C)C(C)C,O=C([O-])[O-].[K+].[K+],test
US20040058964A1,C[Si](C)(C)N=C=O.Cc1cc(OCc2ccc(F)cc2CN)c(Br)c(=O)n1-c1c(F)cccc1F>>Cc1cc(OCc2ccc(F)cc2CNC(N)=O)c(Br)c(=O)n1-c1c(F)cccc1F,,C1CCOC1,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20080021032A1,COCCn1ccc(N)n1.CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)O)cc1C#N>>COCCn1ccc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(C)(=O)=O)c(C#N)c2)n1,CN(C)C=O,ClCCl,,Cc1cccc(C)n1,O=C(Cl)C(=O)Cl,test
US04795487,CC(=O)Cl.CCC(=O)C1=C(O)CC(c2c(C)cc(C)c(CC#N)c2C)CC1=O>>CCC(=O)C1=C(O)CC(c2c(C)c(CC#N)c(C)c(C(C)=O)c2C)CC1=O,,S=C=S,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US05834482,ClCCCn1c2ccccc2c2cc(-c3nc(C4CC4)no3)ncc21.OC1(c2ccccc2)CCNCC1>>Cl.OC1(c2ccccc2)CCN(CCCn2c3ccccc3c3cc(-c4nc(C5CC5)no4)ncc32)CC1,,CN(C)C=O,,,,test
US06235789B1,CC(C)(C)N=C=O.COc1ccc2c(c1)C(=CCN)C(C)(C)CC2>>COc1ccc2c(c1)/C(=C\CNC(=O)NC(C)(C)C)C(C)(C)CC2,,C1CCOC1,,CCOC(C)=O,O,test
US20120129897A1,CCOc1ccc(C#N)cc1Nc1nc(Cl)cs1.Cc1c[nH]c(C)n1>>CCOc1ccc(C#N)cc1Nc1nc(-n2cc(C)nc2C)cs1,,CN(C)C=O,,,,test
US04487779,Cc1ccc(OCc2ccccc2)c(C)c1[N+](=O)[O-]>>Cc1ccc(OCc2ccccc2)c(C)c1N,[Zn],CC(=O)O,,,,test
US20130102776A1,C1CSCCN1.C=O.O=C1/C(=C/c2c[nH]c3ccccc23)Oc2cc(O)ccc21>>O=C1/C(=C/c2c[nH]c3ccccc23)Oc2c1ccc(O)c2CN1CCSCC1,,CCO,,,,test
US20030153557A1,CCOC(=O)C=Cc1ccc(C(=O)OC(C)(C)C)s1>>CCOC(=O)CCc1ccc(C(=O)OC(C)(C)C)s1,[Pd],CCO,,[H][H],,test
US20150291593A1,CC(=O)c1c(O)[nH]c(=O)sc1=O.Nc1ccccc1>>Cc1cc(=O)[nH]c(=O)n1-c1ccccc1,,CN(C)C=O,,,,test
US20120035237A1,CCC(C)CBr.O=C(Nc1c(F)cccc1F)c1ccn(Cc2ccccc2O)n1>>CCC(C)COc1ccccc1Cn1ccc(C(=O)Nc2c(F)cccc2F)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150038528A1,C[C@@H](NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)[C@H](C)C(=O)OC(C)(C)C>>C[C@@H](NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)[C@H](C)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110053933A1,C1CCOC1.CNC.ClCc1ccc(Cl)nc1>>CN(C)C(=O)c1ccc(Cl)nc1,,ClCCl,,,,test
US03932444,CCc1nc(C)c[nH]1.O=S(=O)(Cl)c1c[nH]cn1>>CCc1nc(C)cn1S(=O)(=O)c1c[nH]cn1,,C1CCOC1,,,,test
US20070123505A1,CC(C)(F)C(c1cc(F)cc(-c2nnn[nH]2)c1)C1CN(C(c2ccccc2)c2ccccc2)C1.CI>>Cn1nnnc1-c1cc(F)cc(C(C2CN(C(c3ccccc3)c3ccccc3)C2)C(C)(C)F)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(C(=O)C2C(=O)OC(C)(C)OC2=O)CC1.Nc1n[nH]c2cccc(-c3ccccc3F)c12>>CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4c(-c5ccccc5F)cccc4nn23)CC1,,CC#N,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20110021520A1,CCOC(=O)[C@@](C)(OC[C@](C)(NS(=O)(=O)c1ccccc1[N+](=O)[O-])c1cc(Br)ccc1F)C(F)(F)F.N>>C[C@@](CO[C@](C)(C(N)=O)C(F)(F)F)(NS(=O)(=O)c1ccccc1[N+](=O)[O-])c1cc(Br)ccc1F,,CO,,,,test
US04892875,CC(=O)CC(=O)OCCN1CCN(C(c2ccccc2)c2ccccc2)CC1.COCCOC(=O)/C=C(/C)N.O=Cc1cccc([N+](=O)[O-])c1>>COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OCCN2CCN(C(c3ccccc3)c3ccccc3)CC2)C1c1cccc([N+](=O)[O-])c1,,CC(C)O,,,,test
US04426382,CC(C)CCO.COc1cc2nc(Cl)nc(N)c2cc1OC.O=C(N1CCNCC1)C1(c2ccccc2)CC1>>COc1cc2nc(N3CCN(C(=O)C4(c5ccccc5)CC4)CC3)nc(N)c2cc1OC.Cl.O,,CC(C)CCO,,,,test
US20110201604A1,CNc1ccc(C(=O)OC)cc1N.Nc1nc2ccc(Cl)cc2s1.S=C(n1ccnc1)n1ccnc1>>COC(=O)c1ccc2c(c1)nc(Nc1nc3ccc(Cl)cc3s1)n2C,,ClCCCl,,,,test
US20090088463A1,Nc1ccc(F)cc1F.O=c1c2ccnn2c(=O)c2ccnn12>>O=C(Nc1ccc(F)cc1F)c1cc[nH]n1,CN(C)c1ccncc1,CN(C)C=O,,,,test
US04220778,Cl.c1ccc(CN2CCc3cccc(-c4ccccc4)c3C2)cc1>>Cl.c1ccc(-c2cccc3c2CNCC3)cc1,[Pd],CCO,,,,test
US20100234389A1,CC(C)(C)OC(=O)N1CCN(c2ccnc(Cl)n2)CC1.OB(O)c1cccc(F)c1F>>CC(C)(C)OC(=O)N1CCN(c2ccnc(-c3cccc(F)c3F)n2)CC1,,O,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20060276508A1,CCOC(=O)C(C)(C)Oc1cccc(C(=O)NC2CCNCC2)c1.CCOc1cc(C=O)cc(OCC)c1-n1cccc1>>CCOC(=O)C(C)(C)Oc1cccc(C(=O)NC2CCN(Cc3cc(OCC)c(-n4cccc4)c(OCC)c3)CC2)c1,,CC(=O)O,CCO,CCN(C(C)C)C(C)C,[BH3-]C#N.[Na+],test
US20130310379A1,CC1(C)CC(NC(=O)c2ccc(COc3cccc(Br)c3)cc2)CC(C)(C)N1.Cc1cncc(B(O)O)c1>>Cc1cncc(-c2cccc(OCc3ccc(C(=O)NC4CC(C)(C)NC(C)(C)C4)cc3)c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,O,O=C([O-])[O-].[Na+].[Na+],,test
US20100190747A1,CCN(CC)CC.CCOC(=O)C(N)C(=O)OCC.CCOC(C)=O.O=C([O-])O>>CCOC(=O)C(NC=C(C)C#N)C(=O)OCC,,CCO,,Cl,,test
US20110053891A1,ICCCCI.Nc1nc(O)ncc1F>>Nc1nc(=O)n(CCCCI)cc1F,,CC#N,CCOC(C)=O,,,test
US05132464,CC(=O)/C=C/C[C@H](C)CCC=C(C)C>>CC(=O)CCC[C@H](C)CCCC(C)C,[Ni],CCOC(C)=O,,[H][H],,test
US20110152233A1,CC(C)=O.CC1(C(=O)N2CCC(C(=O)N3CC(N)C(c4ccc(Cl)c(Cl)c4)C3)CC2)CC1>>CC(C)N[C@@H]1CN(C(=O)C2CCN(C(=O)C3(C)CC3)CC2)C[C@H]1c1ccc(Cl)c(Cl)c1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US07439360B2,CC(C)(C)OC(=O)N1CCCCC1CN.C[Si](C)(C)CCOCn1c(N2CCN(c3ncccc3C(F)(F)F)CC2)nc(C(=O)O)c1-c1ccc(C(F)(F)F)cc1>>O=C(NCC1CCCCN1)c1nc(N2CCN(c3ncccc3C(F)(F)F)CC2)[nH]c1-c1ccc(C(F)(F)F)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20140179668A1,C1CCNCC1.CC(C)c1cc(Nc2nc(N3CCCC3C(=O)O)nc3c2CCC3)n[nH]1>>CC(C)c1cc(Nc2nc(N3CCC[C@@H]3C(=O)N3CCCCC3)nc3c2CCC3)n[nH]1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090076001A1,CC(=O)N1CC=C(N2CCCC2)CC1.CCOC(=O)C(Cl)=NO>>CCOC(=O)C1=NOC2(N3CCCC3)CCN(C(C)=O)CC12,,ClCCl,,CCN(CC)CC,,test
US20090221551A1,Cl.NOCc1ccccc1.O=C(CCCBr)Nc1cnc2ccccc2c1Cl>>On1c(CCCCl)nc2cnc3ccccc3c21,,CC(C)O,,,,test
US20100286117A1,CCCc1noc(C)c1C(=O)OCC>>CCCc1noc(C)c1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080096922A1,COc1cccc(C2(C(=O)NS(=O)(=O)Oc3c(C(C)C)cccc3C(C)C)CCC(=O)CC2)c1.Nc1ccccc1>>COc1cccc(C2(C(=O)NS(=O)(=O)Oc3c(C(C)C)cccc3C(C)C)CCC(Nc3ccccc3)CC2)c1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20040235822A1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4nncn4CCCC)cc2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4nncn4CCCC)cc2)CCN3CC(C)C)cc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US03935182,CCN(CCCl)c1ccccc1.CN(C)CCO>>CCN(CC[N+](C)(C)CCO)c1ccccc1.[Cl-],,O,,,,test
US20150141406A1,CCOC(=O)/C=C/c1cc(Br)cn1COCC[Si](C)(C)C>>CCOC(=O)/C=C/c1cc(Br)c[nH]1,,CCOC(C)=O,COCCOC,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090181928A1,CC(C)(C)OC(=O)NCCCCO.COC(=O)c1c(O)cccc1O>>COC(=O)c1c(O)cccc1OCCCCNC(=O)OC(C)(C)C,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060100229A1,Cn1nc(C(N)=O)cc1CCN1C(=O)c2ccccc2C1=O>>Cn1nc(C#N)cc1CCN1C(=O)c2ccccc2C1=O,,ClCCl,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,c1ccncc1,test
US20160263093A1,CC(C)(C)[Si](C)(C)Cl.Cc1ccc2cc(O)ccc2n1>>Cc1ccc2cc(O[Si](C)(C)C(C)(C)C)ccc2n1,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US05972946,CCCNCCC.O=C(Cl)CBr>>CCCN(CCC)C(=O)CBr,,CCOCC,,CCN(CC)CC,,test
US20030055085A1,Cc1ccc(Cl)c(C(O)=S)c1.O=C(Cl)C(=O)Cl>>Cc1ccc(Cl)c(C(=S)Cl)c1,,CN(C)C=O,,,,test
US20050154042A1,CCOC(=O)c1c(C(C)C)c(-c2ccc(F)cc2)cn1CC.CN(C)C=O>>CCOC(=O)c1c(C(C)C)c(-c2ccc(F)cc2)c(C=O)n1CC,,ClCCCl,,O=P(Cl)(Cl)Cl,,test
US04473709,O=C(O)c1ccccc1-c1ccccc1.O=S(Cl)Cl>>O=C(Cl)c1ccccc1-c1ccccc1,,Cc1ccccc1,,c1ccncc1,,test
US20080306082A1,NC1CC1.O=C(O)c1cccc2sc(-c3nc(Cl)ncc3Cl)cc12>>O=C(NC1CC1)c1cccc2sc(-c3nc(Cl)ncc3Cl)cc12,,CCOCC,ClCCl,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20090042841A1,Cc1cccc(C#CC(O)C2CCNCC2)n1.O=[N+]([O-])c1cccnc1Br>>Cc1cccc(C#CC(O)C2CCN(c3ncccc3[N+](=O)[O-])CC2)n1,,CC(=O)N(C)C,,CCN(CC)CC,O,test
US20070287715A1,CC(C)(Oc1ccc(Br)cc1)C(=O)Cl.CO>>COC(=O)C(C)(C)Oc1ccc(Br)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20100216814A1,CC(=CBr)c1ccc(F)cc1.CN1CCc2[nH]c3cc(C(F)(F)F)ccc3c2C1>>C/C(=C\n1c2c(c3ccc(C(F)(F)F)cc31)CN(C)CC2)c1ccc(F)cc1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20110086834A1,CN1CC2(CNc3cc(O)ccc32)C1.Cl.Nc1ncc(Cl)c(Cl)n1>>CN1CC2(C1)CN(c1nc(N)ncc1Cl)c1cc(O)ccc12.Cl,,Cl,,,,test
US20060135552A1,CC(=O)CC(=O)C1CC1.Nc1sc2c(c1C(=O)c1cccs1)CCC2>>Cc1nc2sc3c(c2c(-c2cccs2)c1C(=O)C1CC1)CCC3,O=S(=O)(O)O,CC(=O)O,,,,test
US20160168090A1,CC(C)(C)OC(=O)N1CC[C@H]1Cn1cc(C(=O)NCC2CCC(F)(F)CC2)c2c(Cl)cccc21>>O=C(NCC1CCC(F)(F)CC1)c1cn(C[C@@H]2CCN2)c2cccc(Cl)c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140179680A1,C=C(c1ccccc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@@H]1CC[C@@H](C)CC1.CO>>COCC(c1ccccc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@@H]1CC[C@@H](C)CC1,,CO,,C[O-].[Na+],,test
US20100056521A1,CCOC(=O)c1ccc(-n2cc(C#N)c3c(OCc4ccccc4)cccc32)cc1>>N#Cc1cn(-c2ccc(C(=O)O)cc2)c2cccc(OCc3ccccc3)c12,,CCO,,[Na+].[OH-],,test
US20010001799A1,CCOC(=O)C(Nc1ccc(C#N)cc1)c1cc(C#C[Si](C)(C)C)cc(CN2CCCC2)c1>>C#Cc1cc(CN2CCCC2)cc(C(Nc2ccc(C#N)cc2)C(=O)OCC)c1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20090137595A1,CC(=O)OCC(=O)CCl.Nc1ccc(I)nn1>>OCc1cn2nc(I)ccc2n1,,CCO,,O=C([O-])O.[Na+],,test
US20110098429A1,CC(=O)c1cccc(-c2ccccc2)c1OCc1ccccc1.COc1ccccc1-c1cccc(Br)c1>>COc1ccccc1-c1cccc(C(C)(O)c2cccc(-c3ccccc3)c2OCc2ccccc2)c1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20130217702A1,Cn1nnc(-c2c(Cl)c3ccccc3n2-c2ccc(CNC(=O)C3(NC(=O)C(F)(F)F)CC3)c(F)c2)n1.O=C(O)c1cc(C2CC2)on1>>Cn1nnc(-c2c(Cl)c3ccccc3n2-c2ccc(CNC(=O)C3(NC(=O)c4cc(C5CC5)on4)CC3)cc2)n1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150152096A1,CCOC(=O)C1=C(C)NC(c2nccs2)=NC1c1ccccc1C(F)(F)F.O=C1CCC(=O)N1Br>>CCOC(=O)C1=C(CBr)NC(c2nccs2)=NC1c1ccccc1C(F)(F)F,,ClC(Cl)(Cl)Cl,,,,test
US20060173018A1,Cc1ccc2c(Cl)nc(-c3ccccc3O)nc2c1.O=C(NCC1CCCNC1)OCc1ccccc1>>Cc1ccc2c(N3CCCC(CNC(=O)OCc4ccccc4)C3)nc(-c3ccccc3O)nc2c1,,ClCCl,,CCN(CC)CC,Cl,test
US20150225373A1,C#C[Si](C(C)C)(C(C)C)C(C)C.Nc1cc(Br)cc(C(=O)NCCN2CCOCC2)c1>>CC(C)[Si](C#Cc1cc(N)cc(C(=O)NCCN2CCOCC2)c1)(C(C)C)C(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US20120258949A1,CC(=O)N1CC2(CC(=O)c3cc(/C=C/C(=O)NOC4CCCCO4)ccc3O2)C1>>CC(=O)N1CC2(CC(=O)c3cc(/C=C/C(=O)NO)ccc3O2)C1,,C1COCCO1,ClCCl,Cl,,test
US05624950,CC1(C)C=CC(=O)CC1.CCCCOCN(Cc1ccccc1)C[Si](C)(C)C>>CC1(C)CCC(=O)C2CN(Cc3ccccc3)CC21,O=C(O)C(F)(F)F,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20070238718A1,CC(=O)Nc1nc2c(s1)-c1c(c(C3CC3)nn1-c1ccc(CC(=O)O)cc1Cl)CC2.N>>CC(=O)Nc1nc2c(s1)-c1c(c(C3CC3)nn1-c1ccc(CC(N)=O)cc1Cl)CC2,,CCO,ClCCl,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090298807A1,COC(=O)c1ccc(C(=O)N2CCOC3(CCNCC3)C2)s1.OCCc1cccc(CBr)c1>>COC(=O)c1ccc(C(=O)N2CCOC3(CCN(Cc4cccc(CCO)c4)CC3)C2)s1,,CC#N,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20120065231A1,CCCN.N#Cc1sc(Br)cc1Br>>CCCNc1cc(Br)c(C#N)s1,,O,,,,test
US20040215014A1,Cc1nc(C(=O)N2CCCCC2Cc2ncc(-c3ccccc3Br)[nH]2)c(-c2ccc(F)cc2)s1.N#C[Cu]>>Cc1nc(C(=O)N2CCCCC2Cc2ncc(-c3ccccc3C#N)[nH]2)c(-c2ccc(F)cc2)s1,,CCOC(C)=O,CN1CCCC1=O,O,,test
US20080275029A1,N[C@H]1CC[C@H](N)CC1.O=c1[nH]c(=O)c2ccc(F)cc2[nH]1>>N[C@@H]1CC[C@@H](Nc2ccc3c(=O)[nH]c(=O)[nH]c3c2)CC1,,O,,,,test
US20080242866A1,Cn1cc2ccc(N)cc2n1.O=C1C(=O)N(C(=O)OC(=O)N2C(=O)C(=O)c3ccccc32)c2ccccc21>>Cn1cc2ccc(NC(=O)c3ccccc3N)cc2n1,,CCC(C)O,,CC(=O)O,,test
US20100173890A1,Nc1cccc(Cl)c1.O=S(=O)(Cl)c1cc(Cl)c2c(c1)CN1CCCC1CO2>>O=S(=O)(Nc1cccc(Cl)c1)c1cc(Cl)c2c(c1)CN1CCCC1CO2,,CC#N,ClC(Cl)Cl,c1ccncc1,,test
US20130116247A1,COc1ccc2c(c1C=O)CCNC2.O=C(n1ccnc1)n1ccnc1>>COc1ccc2c(c1C=O)CCN(C(=O)n1ccnc1)C2,,C1CCOC1,,,,test
US20160159752A1,C[C@@H](O)CN.[N-]=[N+]=N[C@H](C(=O)Nc1cccc(F)c1CCC1C[N@@]1S(=O)(=O)c1ccccc1)C(c1cccc(F)c1)c1cccc(F)c1>>C[C@@H](O)CNC[C@H](CCc1c(F)cccc1NC(=O)[C@@H](N=[N+]=[N-])C(c1cccc(F)c1)c1cccc(F)c1)NS(=O)(=O)c1ccccc1,,ClCCCl,O,,,test
US20160024017A1,CN(CCN(C)C(=O)OC(C)(C)C)Cc1nn(C2CCCCO2)c2ccc(C3=CCCCC3)cc12>>CN(CCN(C)C(=O)OC(C)(C)C)Cc1nn(C2CCCCO2)c2ccc(C3CCCCC3)cc12,[Pd],CO,,[H][H],,test
US20130150342A1,CN(C)C(=O)c1cc2cnc(Nc3ccc(N4C[C@@H]5CC[C@H](CC4=O)N5)cn3)nc2n1C1CCCC1.CS(=O)(=O)Cl>>CN(C)C(=O)c1cc2cnc(Nc3ccc(N4C[C@@H]5CC[C@H](CC4=O)N5S(C)(=O)=O)cn3)nc2n1C1CCCC1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,ClCCl,test
US20100280010A1,COc1ccc([C@H](C)N[C@H]2CCCc3cccnc32)cc1.O=Cc1cn2c(F)cccc2n1>>COc1ccc([C@H](C)N(Cc2cn3c(F)cccc3n2)[C@H]2CCCc3cccnc32)cc1,,CC(Cl)Cl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160031876A1,COC(=O)[C@@]1(c2cccc(F)c2C)CC[C@H](O)C1>>Cc1c(F)cccc1[C@@]12CC[C@@H](C1)OC2=O,,CC#N,,C1CCC2=NCCCN2CC1,,test
US06399627B1,CCOC(=O)CC(=O)C(F)(F)F.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)/C=C(\OS(=O)(=O)C(F)(F)F)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US04859692,CC(=O)OC(C)=O.COc1cc(C(=O)O)ccc1Cc1c[nH]c2ccc([N+](=O)[O-])cc12>>COc1cc(C(=O)O)ccc1Cc1cn(C(C)=O)c2ccc([N+](=O)[O-])cc12,,CN(C)C=O,,Cl,[H-].[Na+],test
US20140378475A1,CC(C)(O)c1ccc2c(c1)[nH]c1c(C(N)=O)cc(Cl)c(Br)c12.Cn1c(=O)o/c(=N\c2cccc(B3OC(C)(C)C(C)(C)O3)c2Cl)c2ccccc21>>Cn1c(=O)n(-c2cccc(-c3c(Cl)cc(C(N)=O)c4[nH]c5cc(C(C)(C)O)ccc5c34)c2Cl)c(=O)c2ccccc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US05747498,COc1cc2ncnc(Cl)c2cc1OC.C[Si](C)(C)C#Cc1cc(N)ccc1F>>C#Cc1cccc(Nc2ncnc3cc(OC)c(OC)cc23)c1.Cl,,CC(C)(C)O,,,,test
US03932429,CI.COc1cccc(C23CCCC(C2)NC3=O)c1>>COc1cccc(C23CCCC(C2)N(C)C3=O)c1,,CS(C)=O,,[H-].[Na+],,test
US20150376160A1,CCOC(=O)C1(c2ccc(-c3ccc(-c4sc(F)cc4NC(=O)O[C@H](C)c4ccccc4C)cc3)cc2)CC1>>Cc1ccccc1[C@@H](C)OC(=O)Nc1cc(F)sc1-c1ccc(-c2ccc(C3(C(=O)O)CC3)cc2)cc1,,CC(C)O,,Cl,[Na+].[OH-],test
US20080076777A1,CC(C)(C)OC(=O)N1CCN(c2ccccc2NC(=O)c2ccnc(Cl)c2)CC1.CI>>CN(C(=O)c1ccnc(Cl)c1)c1ccccc1N1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20040097485A1,CCOP(=O)(CC#N)OCC.O=Cc1cc(Br)cs1>>N#CC=Cc1cc(Br)cs1,,C1CCOC1,Cc1ccccc1,[Cl-].[NH4+],,test
US20130225620A1,Clc1nccc(Nc2cc(C3CC3)n[nH]2)n1.NCc1cc2ncn(C3CCCCO3)c2cc1F>>Fc1cc2c(cc1CNc1nccc(Nc3cc(C4CC4)[nH]n3)n1)ncn2C1CCCCO1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20040038961A1,Fc1cccc(CBr)c1.Oc1nccc2ncc(Br)cc12>>O=c1c2cc(Br)cnc2ccn1Cc1cccc(F)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080269208A1,CC(C)(C)OC(=O)N1CCC[C@H]1CNC(=O)OCc1ccccc1>>O=C(NC[C@@H]1CCCN1)OCc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120270863A1,COC(=O)c1ccccc1NC(=O)/C=C1\CNC(=O)c2cc(OC)c(OC)cc21>>COc1cc2c(cc1OC)/C(=C/C(=O)Nc1ccccc1C(=O)O)CNC2=O,,C1CCOC1,CO,[Li+].[OH-],,test
US20040013974A1,CS(=O)(=O)Cl.N#CC(=NO)c1ccsc1>>CS(=O)(=O)ON=C(C#N)c1ccsc1,,C1CCOC1,,CCN(CC)CC,,test
US20030232853A1,COC(=O)c1ccc2cc(/C=N\O)oc2c1>>COC(=O)c1ccc2cc(C#N)oc2c1,,ClCCl,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,c1ccncc1,test
US20080269233A1,COC(=O)[C@@H]1CNC[C@H]1c1ccc(F)cc1F.N#Cc1ccc(Cl)nc1>>COC(=O)[C@@H]1CN(c2ccc(C#N)cn2)C[C@H]1c1ccc(F)cc1F,,CC#N,,CCN(C(C)C)C(C)C,,test
US20110118248A1,COCCl.CON(C)C(=O)c1ncc(C)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1>>COCN(c1cc(C)cnc1C(=O)N(C)OC)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20160068545A1,C=CC[C@H](C)[C@@H](C)S(N)(=O)=O.C=C[C@H](O)[C@@H]1CC[C@H]1CN1C[C@@]2(CCCc3cc(Cl)ccc32)COc2ccc(C(=O)O)cc21>>C=CC[C@H](C)[C@@H](C)S(=O)(=O)NC(=O)c1ccc2c(c1)N(C[C@@H]1CC[C@H]1[C@@H](O)C=C)C[C@@]1(CCCc3cc(Cl)ccc31)CO2,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US06740650B2,COc1ccc2ccc(O)c([N+](=O)[O-])c2c1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1ccc2ccc(OS(=O)(=O)C(F)(F)F)c([N+](=O)[O-])c2c1,,C1CCOC1,,[H-].[Na+],,test
US20150152113A1,COc1cc(OC)nc(C2CCN(c3cnnc(NNC(=O)CC(F)(F)F)c3Cl)CC2)n1>>COc1cc(OC)nc(C2CCN(c3cnn4c(CC(F)(F)F)nnc4c3Cl)CC2)n1,,CC#N,,O=P(Cl)(Cl)Cl,,test
US20050267185A1,BrCc1ccccc1.Sc1nc(Nc2ccccc2)n[nH]1>>c1ccc(CSc2nc(Nc3ccccc3)n[nH]2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150175599A1,Cc1cc2ncccc2[nH]1.ClCc1ccc(Cl)cc1>>Cc1cc2ncccc2n1Cc1ccc(Cl)cc1,,CS(C)=O,O,[K+].[OH-],,test
US20120295884A1,NC(=O)c1nn(CC(=O)O)c2ccccc12.O=C(Nc1cccc(Br)n1)[C@@H]1C[C@H]2C[C@H]2N1>>NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccccc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040058912A1,COc1cc(C(=O)Cc2ccc(Cl)c(Cl)c2)c([N+](=O)[O-])cc1OC>>COc1cc(N)c(C(=O)Cc2ccc(Cl)c(Cl)c2)cc1OC,[Pd],CO,,,,test
US20150284395A1,CCI.CCOC(C)=O.O=C(O)c1ccc(Cl)c(O)c1>>CCOC(=O)c1ccc(Cl)c(OCC)c1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05939268,C#CCN.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)CC#CN,,C1CCOC1,,,,test
US20150025068A1,Nc1ccc(C(=O)O)c(O)c1.O=S(=O)(Cl)c1cc(Cl)sc1Cl>>O=C(O)c1ccc(NS(=O)(=O)c2cc(Cl)sc2Cl)cc1O,,C1COCCO1,O,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US20110053933A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC(Oc2ccc(Cl)cc2)CC1.Cl>>C[C@H](N)C(=O)N1CCC(Oc2ccc(Cl)cc2)CC1.Cl,,C1COCCO1,,,,test
US20120245144A1,CC(C)(Br)C(N)=O.CC(C)n1ncnc1-c1cn2c(n1)-c1cc(SC3CCNCC3)ccc1OCC2>>CC(C)n1ncnc1-c1cn2c(n1)-c1cc(SC3CCN(C(C)(C)C(N)=O)CC3)ccc1OCC2,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040010141A1,N#Cc1ccc(-n2ncc3cc(Oc4ccc([N+](=O)[O-])cn4)ccc32)cc1>>N#Cc1ccc(-n2ncc3cc(Oc4ccc(N)cn4)ccc32)cc1,O=[Pt]=O,CO,,CCOC(C)=O,,test
US20120172348A1,CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](O)C[C@@H]1C(=O)O3.O=C(Cl)c1ccco1>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](OC(=O)c2ccco2)C[C@@H]1C(=O)O3,,ClCCl,,c1ccncc1,O=C([O-])O.[Na+],test
US05212195,C=CC=CC(=O)OC.[C-]#[N+]CS(=O)(=O)C1(CCCC)C=CC(C)=CC1>>CCCCc1cc(C=CC(=O)OC)c[nH]1,,CCOCC,CS(C)=O,[H-].[Na+],[Cl-].[NH4+],test
US06653334B1,CCOC(=O)CCc1cccc(OC(C)(C)C(=O)OC(C)(C)C)c1>>CC(C)(C)OC(=O)C(C)(C)Oc1cccc(CCC(=O)O)c1,,CCO,,[K+].[OH-],,test
US06013658,COC(=O)c1nc([C@@H](Cc2ccc3ccccc3c2)NC(=O)OC(C)(C)C)sc1-c1ccccc1>>CC(C)(C)OC(=O)N[C@H](Cc1ccc2ccccc2c1)c1nc(C(=O)O)c(-c2ccccc2)s1,,CCO,,[Li+].[OH-],,test
US04076823,C1N2CN3CN1CN(C2)C3.Cc1nc2n(n1)C(N)(c1ccccc1)c1cc(Cl)ccc1-2>>Cc1nc2n(n1)CN=C(c1ccccc1)c1cc(Cl)ccc1-2,,COCCOC,,Cl,,test
US20090306057A1,CCOC(=O)C(C)(CC=C(C)C)C(=O)OCC>>CCOC(=O)C(C)(CCC(C)C)C(=O)OCC,[Pd],CCOC(C)=O,,,,test
US20110077248A1,CCOC(=O)c1cccnc1N.O=Cc1ccc(C(=O)CBr)cc1>>CCOC(=O)c1cccn2cc(-c3ccc(C=O)cc3)nc12,,CC#N,,,,test
US20120295884A1,O=C(Cl)OCc1ccccc1.O=C(Nc1cccc(OC(F)(F)F)c1)[C@@H]1CC[C@H](CO)N1>>O=C(Nc1cccc(OC(F)(F)F)c1)[C@@H]1CC[C@H](CO)N1C(=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
US05254546,CCCc1nc(-c2cccc3ccccc23)c(C=O)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCc1nc(-c2cccc3ccccc23)c(C=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,C1CCOC1,,Cl,,test
US20150291659A1,COc1ccc2c(c1)NC(=O)[C@@H](C)NC(=O)CNC(=O)CCCC=C2>>COc1ccc2c(c1)NC(=O)[C@@H](C)NC(=O)CNC(=O)CCCCC2,[Pd],CCO,,,,test
US20070060587A1,O=C1c2ccccc2C(=O)N1CCCc1ccccn1>>NCCCc1ccccn1,,CO,,NN,,test
US04769367,CC=O.COc1cccc(F)c1>>COc1cccc(F)c1C(C)O,,C1CCOC1,,Cl,[Li]CCCC,test
US20150141406A1,CC1(C)OB(c2ccc(S(N)(=O)=O)cc2)OC1(C)C.COc1nccc2c1c(I)cn2[C@@H]1CC[C@@H](O[Si](C)(C)C(C)(C)C)CC1>>COc1nccc2c1c(-c1ccc(S(N)(=O)=O)cc1)cn2[C@@H]1CC[C@@H](O[Si](C)(C)C(C)(C)C)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05824811,CC(=O)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>CC(=O)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100239576A1,CC(C)(C)OC(=O)NCC(=O)O.Cc1c(C(=O)OCc2ccccc2)c(=O)n(-c2ccccc2)n1C[C@@H](C)O>>Cc1c(C(=O)OCc2ccccc2)c(=O)n(-c2ccccc2)n1C[C@@H](C)OC(=O)CNC(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20090163586A1,N.NS(=O)(=O)c1cc(C(=O)O)ccc1NS(=O)(=O)c1cccc(-c2ccc(Cl)c(Cl)c2)c1>>NC(=O)c1ccc(NS(=O)(=O)c2cccc(-c3ccc(Cl)c(Cl)c3)c2)c(S(N)(=O)=O)c1,,CN(C)C=O,,Cl,O=C(n1ccnc1)n1ccnc1,test
US20100240642A1,CC(C)(C)c1ccc(B(O)O)cc1.CCOC(=O)c1c(Br)c2ccccc2n1Cc1cccc(-c2ccc(OCc3ccccc3)cc2)c1>>CCOC(=O)c1c(-c2ccc(C(C)(C)C)cc2)c2ccccc2n1Cc1cccc(-c2ccc(OCc3ccccc3)cc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US05498609,CS(=O)(=O)Cl.O=C(Nc1ccc(C(=O)N2CCCCc3cc(Cl)ccc32)cn1)c1ccccc1OCCO>>CS(=O)(=O)OCCOc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCCc3cc(Cl)ccc32)cn1,,O,,c1ccncc1,,test
US20130116216A1,O=C(NC1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CC1)OCc1ccccc1>>Nc1ccc(S(=O)(=O)N2CCC(NC(=O)OCc3ccccc3)CC2)cc1,[Fe],O,,CCO,[Cl-].[NH4+],test
US05833885,C=C1N(C)c2ccccc2C1(C)C.O=Nc1c(O)cc(N2CCCCC2)c2oc3ccccc3c12>>CN1c2ccccc2C(C)(C)C12CNc1c(cc(N3CCCCC3)c3oc4ccccc4c13)O2,,CO,,,,test
US20100210635A1,COC(=O)CCc1ccccc1Oc1ccccc1CCC(=O)N1CCN(C(=O)OC(C)(C)C)C[C@H]1Cc1ccccc1>>CC(C)(C)OC(=O)N1CCN(C(=O)CCc2ccccc2Oc2ccccc2CCC(=O)O)[C@H](Cc2ccccc2)C1,,CCO,,Cl,[Na+].[OH-],test
US04167638,CC(Br)CCCN1C(=O)c2ccccc2C1=O.COc1cc(N)c2ncccc2c1N(C)C>>COc1cc(NC(C)CCCN2C(=O)c3ccccc3C2=O)c2ncccc2c1N(C)C,,CC(C)=O,,CCN(CC)CC,,test
US20100056506A1,COC(=O)c1cccc(O)c1[N+](=O)[O-].CS(=O)(=O)OC1CCOCC1>>COC(=O)c1cccc(OC2CCOCC2)c1[N+](=O)[O-],,CC#N,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20160150782A1,CCc1cc(C(=O)OC)c(=O)[nH]c1C(F)(F)C(F)(F)F.NC1CC1>>CCc1cc(C(=O)NC2CC2)c(=O)[nH]c1C(F)(F)C(F)(F)F,,CC#N,,Cl,,test
US20050037999A1,BrCC1CC1.Clc1ncnc2[nH]ccc12>>Clc1ncnc2c1ccn2CC1CC1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05559256,CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CN(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NC(CC1CCCCC1)C(O)CNCC(O)C(CC1CCCCC1)NC(=O)OC(C)(C)C,,CO,,,,test
US20090082359A1,C1CCNC1.Cl.O=c1cc(-c2ccc(C(F)(F)F)cc2)ccn1-c1ccc2c(cnn2C[C@@H]2CO2)c1>>Cl.O=c1cc(-c2ccc(C(F)(F)F)cc2)ccn1-c1ccc2c(cnn2C[C@@H](O)CN2CCCC2)c1,,C1CCOC1,ClCCl,,,test
US20080167310A1,COC(=O)CC(=O)C(C)Br.O=C(O)c1ccc(-c2ccccc2)cc1>>COC(=O)CC(=O)C(C)OC(=O)c1ccc(-c2ccccc2)cc1,,CC(C)=O,,CCN(CC)CC,O,test
US20110105461A1,CCN.Cc1ccc(S(=O)(=O)OC[C@H]2COc3ccc(S(C)(=O)=O)cc3O2)cc1>>CCNC[C@H]1COc2ccc(S(C)(=O)=O)cc2O1,,CC#N,,,,test
US20130324528A1,NN.O=Cc1ncc(F)c(Cl)c1F>>Fc1cnc2cn[nH]c2c1Cl,,CCCCO,,,,test
US20160181549A1,Cc1cccc(C)c1-c1cccc([N+](=O)[O-])c1>>Cc1cccc(C)c1-c1cccc(N)c1,[Pd],,,[H][H],,test
US20120316151A1,O=C(C[C@@H]1CCN(C(=O)C2CC2)C1)NNC(=O)Nc1cc(Cl)c(Br)cc1F>>O=C(C1CC1)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2cc(Cl)c(Br)cc2F)C1,,O,,O=C([O-])[O-].[K+].[K+],,test
US04709062,C=CC(=O)NCO.Cc1ccc(O)c(C)c1>>C=CC(=O)NCc1cc(C)cc(C)c1O,Cc1ccc(S(=O)(=O)O)cc1,O,,CC(C)=O,,test
US06329381B1,CCCCOc1nc(N)c2nc(OC)n(Cc3ccccc3)c2n1>>CCCCOc1nc(N)c2nc(O)n(Cc3ccccc3)c2n1,,Cl,,N,,test
US20130029971A1,COC(=O)C1CCN(c2ncc(Cl)cc2N)CC1.O=C(Cl)c1cccc(Cl)c1>>COC(=O)C1CCN(c2ncc(Cl)cc2NC(=O)c2cccc(Cl)c2)CC1,,CC#N,CO,,,test
US20130019348A1,CC(C)c1ccccc1N=C=S.N#CCC(=O)Nc1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1>>CC(C)c1ccccc1N/C(S)=C(\C#N)C(=O)Nc1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20150376136A1,CCOC(=O)C(C)(CC1CCCCC1)C(C)=O.NN>>CC1=NNC(=O)C1(C)CC1CCCCC1,,CCO,,,,test
US20110086810A1,COc1nc(-c2cnn(C(CC#N)C3CCCC3)c2)c2cc[nH]c2n1.O=C1CCC(=O)N1I>>COc1nc(-c2cnn([C@H](CC#N)C3CCCC3)c2)c2c(I)c[nH]c2n1,,C1CCOC1,,,,test
US20060122181A1,O=Cc1ccc(Br)s1.OCc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2ccc(CO)cc2)s1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CO,,O=C([O-])[O-].[K+].[K+],,test
US20110054173A1,Fc1nc(F)c(F)c(C(F)(F)F)c1F.Oc1ccc(CCNc2ncnc3nccnc23)cc1>>Fc1nc(Oc2ccc(CCNc3ncnc4nccnc34)cc2)c(F)c(C(F)(F)F)c1F,,CN(C)C=O,,CCN(CC)CC,,test
US03946025,ClCSc1ccccc1Br.Nc1ccccn1>>Nc1cccc[n+]1CSc1ccccc1Br.[Cl-],,Cc1ccccc1C,,,,test
US20090054427A1,BrP(Br)Br.CCCCc1cc(CO)cc(F)c1NC(=O)OCc1ccccc1>>CCCCc1cc(CBr)cc(F)c1NC(=O)OCc1ccccc1,,CCOCC,,CO,,test
US20050192268A1,COC(=O)c1ccccc1S.O=[N+]([O-])c1ccc(Cl)cc1F>>COC(=O)c1ccccc1Sc1ccc(Cl)cc1[N+](=O)[O-],,CN(C)C=O,,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],test
US04427665,CC(C)(C)C(=O)OCOP(=O)(CCCCc1ccccc1)CC(=O)N1Cc2ccccc2C[C@H]1C(=O)OCc1ccccc1>>CC(C)(C)C(=O)OCOP(=O)(CCCCc1ccccc1)CC(=O)N1Cc2ccccc2C[C@H]1C(=O)O,[Pd],CO,,,,test
US20040122244A1,CC(C)(C)OC(=O)c1cccnc1N.COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)O)c2)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)Nc3ncccc3C(=O)OC(C)(C)C)c2)=C(C)C1=O,,ClCCl,,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US20080318990A1,O=C(/C=C/c1cc(F)cc(F)c1)N1CCC(CO)CC1>>O=CC1CCN(C(=O)/C=C/c2cc(F)cc(F)c2)CC1,,ClCCl,,CS(C)=O,O=C(Cl)C(=O)Cl,test
US05405851,CC(C)(C)C(=O)Nc1nc2ccc3ccc(Br)cc3c2c(=O)[nH]1>>Nc1nc2ccc3ccc(Br)cc3c2c(=O)[nH]1,,[Na+],[OH-],CC(=O)O,,test
US20130059863A1,CCC(CCNc1cnc(Cl)nc1)(CCOC)C(=O)OC>>O=C1N(c2cnc(Cl)nc2)CCC12CCOCC2,,C1CCOC1,CCOC(C)=O,CC(C)(C)[O-].[K+],,test
US20020193385A1,CN(C)CCON.N#Cc1ccccc1-c1cc(-c2cnc3nc(C=O)ccn23)ccc1F>>N#Cc1ccccc1-c1cc(-c2cnc3nc(C=NO)ccn23)ccc1F,,CCO,,,,test
US20090048269A1,CN1CCC(N)CC1.Nc1ccc(C(=O)O)cc1>>CN1CCC(NC(=O)c2ccc(N)cc2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US03960868,CCOC(=O)c1cn(CC)c2cc(C3CCCCC3)c(OC)cc2c1=O>>CCn1cc(C(=O)O)c(=O)c2cc(OC)c(C3CCCCC3)cc21,,CCO,,[Na+].[OH-],,test
US06376491B1,Cc1c(COc2ccc3oc(CO)cc3c2)oc2cccc(OCCCNCc3cccnc3)c12.OCC(F)(F)F>>Cc1c(COc2ccc3oc(COCC(F)(F)F)cc3c2)oc2cccc(OCCCNCc3cccnc3)c12,,c1ccccc1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20070197558A1,COc1ccc(Sc2cc(C)cc(N)c2)cc1>>Cc1cc(N)cc(Sc2ccc(O)cc2)c1,,ClCCl,,BrB(Br)Br,,test
US20020035102A1,CN1CCNCC1.CS(=O)(=O)C(=C1CN([C@@H](c2ccc(Cl)cc2)c2ccc(CCl)cc2)C1)c1cc(F)cc(F)c1>>CN1CCN(Cc2ccc([C@H](c3ccc(Cl)cc3)N3CC(=C(c4cc(F)cc(F)c4)S(C)(=O)=O)C3)cc2)CC1,,ClCCl,,,,test
US20070259821A1,C[Si](C)(C)c1ccc(Cc2cc([C@@]3(O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc2C#N)cc1.ClI>>N#Cc1ccc([C@@]2(O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1Cc1ccc(I)cc1,,ClCCl,,,,test
US05244908,O=C1c2ccccc2C(=O)N1CCCCCCBr.Sc1cccc2nccn12>>O=C1c2ccccc2C(=O)N1CCCCCCSc1cccc2nccn12,,CCO,,CCN(CC)CC,,test
US05070089,COc1ccc(C(=O)O)c(OC)c1OC.CSC(=S)N1CCNCC1>>COc1ccc(C(=O)N2CCN(C(=S)SC)CC2)c(OC)c1OC,,ClCCl,,CCN(CC)CC,O=S(Cl)Cl,test
US04383945,CC(OC(=O)OCc1ccc([N+](=O)[O-])cc1)[C@H]1C(=O)N[C@@H]1CC=O>>CC(OC(=O)OCc1ccc([N+](=O)[O-])cc1)[C@H]1C(=O)N[C@@H]1CCO,CC(=O)O,CO,,[BH4-].[Na+],,test
US20070244155A1,C=C(Br)CBr.COC(=O)/C=C/c1ccc(OCc2sc(-c3ccc(C)cc3)nc2C)cc1O>>C=C(Br)COc1cc(OCc2sc(-c3ccc(C)cc3)nc2C)ccc1/C=C/C(=O)OC,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],test
US05863918,COC(=O)C1(C)CCc2c(OC)cccc2C1=O>>COC(=O)C1(C)CCc2c(cccc2OC)C1,,O=C(O)C(F)(F)F,,CCOC(C)=O,O,test
US20150291563A1,COC(=O)C1=NN(c2ccccc2Cl)C(c2ccc(Br)c(F)c2)C1>>O=C(O)C1=NN(c2ccccc2Cl)C(c2ccc(Br)c(F)c2)C1,,O,,CO,[K+].[OH-],test
US20040014753A1,COC(=O)C1CCCC2CC=CCC(NC(=O)c3ccccc3)C(=O)N21>>O=C(N[C@H]1CC=CC[C@H]2CCC[C@@H](C(=O)O)N2C1=O)c1ccccc1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20090221555A1,COc1c([N+](=O)[O-])cc(Cl)c2c1C(=O)C[C@@H](NC(C)=O)CC2>>COc1c([N+](=O)[O-])cc(Cl)c2c1C(O)C[C@@H](NC(C)=O)CC2,,CO,,O,[BH4-].[Na+],test
US20080009488A1,CN1CCNCC1.O=C(Cc1nc2ccc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)cc2[nH]1)OCCCCl>>CN1CCN(CCCOC(=O)Cc2nc3ccc(C4(O)c5ccccc5C(=O)N4Cc4ccccc4)cc3[nH]2)CC1,,CC#N,,,,test
US20030100576A1,CC(C)(C)OC(=O)NC1CCCC(CNC(=O)OCc2ccccc2)C1>>NC1CCCC(CNC(=O)OCc2ccccc2)C1,,O=C(O)C(F)(F)F,,,,test
US05561101,Cc1ccccc1C1=NC(C)(C)CO1.Clc1cc(Cl)ncn1>>CC1(C)COC(c2ccccc2Cc2nc(Cl)cc(Cl)n2)=N1,,CCCCCC,CCOCC,[Li]CCCC,,test
US04357340,Cc1ccc(Cn2ccnc2)cc1C.O=C(O)C(=O)O>>Cc1ccc(Cn2ccnc2)cc1C.O=C(O)C(=O)O,,CCO,,,,test
US20050043328A1,Clc1ncnc2nc[nH]c12.NCc1cccc(Cl)c1>>Clc1cccc(CNc2ncnc3nc[nH]c23)c1,,CCCCO,,CCN(CC)CC,,test
US20100004238A1,Nc1ccc(Oc2ccnc3c(C(F)(F)F)cccc23)c(Cl)c1.O=C(OCCn1ccc2ncnc(Cl)c21)c1ccccc1>>OCCn1ccc2ncnc(Nc3ccc(Oc4ccnc5c(C(F)(F)F)cccc45)c(Cl)c3)c21,,CC(C)O,,Cl,c1ccncc1,test
US20150368210A1,CC(C)(O)C(C)(C)O.O=Cc1cccc(B(O)O)c1>>CC1(C)OB(c2cccc(C=O)c2)OC1(C)C,,C1CCOC1,ClCCl,,,test
US04810708,COC(=O)c1cccnc1Nc1ccccc1.COc1ccc2c(c1)CCCC2=O>>COc1ccc2c(c1)CCc1c-2n(-c2ccccc2)c2ncccc2c1=O,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20130116243A1,CON=C1CCCc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)cc21>>CON=C1CCCc2nc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)cc21,,O=C(O)C(F)(F)F,,,,test
US20040058978A1,CC(C)(C)OC(=O)NCc1ccc(N)cc1.CCOC(=C1C(=O)N(C(C)=O)c2ccc([N+](=O)[O-])cc21)c1ccccc1>>CC(C)(C)OC(=O)NCc1ccc(N/C(=C2\C(=O)Nc3ccc([N+](=O)[O-])cc32)c2ccccc2)cc1,,CN(C)C=O,CO,[Na+].[OH-],,test
US20060173019A1,CC(C)Nc1ccccc1.COCN(c1cc(Cl)cnc1C(=O)O)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1>>COCN(c1cc(Cl)cnc1C(=O)N(c1ccccc1)C(C)C)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1,,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US04952580,O=C(O)CCC(F)=C(F)F>>OCCCC(F)=C(F)F,,CCOCC,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20110059954A1,COc1ccc2c(c1)CCN(C1CCNCC1)C(=O)N2.Cc1nc(Cl)cc(C(=O)c2cc(C)c3[nH]c(=O)oc3c2)n1>>COc1ccc2c(c1)CCN(C1CCN(c3cc(C(=O)c4cc(C)c5[nH]c(=O)oc5c4)nc(C)n3)CC1)C(=O)N2,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US06627651B1,COC(=O)C1=Cc2cc(O)ccc2CCC1.OC1CCCCC1>>COC(=O)C1=Cc2cc(OC3CCCCC3)ccc2CCC1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060052449A1,CN(C)CCN.O=C(O)c1ccccc1-c1ccc(CSCCOc2ccccc2)cc1>>CN(C)CCNC(=O)c1ccccc1-c1ccc(CSCCOc2ccccc2)cc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20040058903A1,C#Cc1ccc(N)cc1.O=C(Cl)c1ccccc1-c1ccc(C(F)(F)F)cc1>>C#Cc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1,,C1CCOC1,O,CCN(CC)CC,CCOC(C)=O,test
US20050245514A1,CCC(O[Si](CC)(CC)CC)C(C)C1OC1CC(C)(/C=C/C=C(\C)C1OC(=O)CC(O[Si](CC)(CC)CC)CCC(C)C(OC(=O)N2CCN(CC(C)(C)C)CC2)C=CC1C)O[Si](CC)(CC)CC>>CCC(O)C(C)C1OC1CC(C)(O)/C=C/C=C(\C)C1OC(=O)CC(O)CCC(C)C(OC(=O)N2CCN(CC(C)(C)C)CC2)C=CC1C,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20050009895A1,CC(=O)OC(C)=O.Cc1ccc(C(=N)NO)cc1[N+](=O)[O-]>>Cc1nc(-c2ccc(C)c([N+](=O)[O-])c2)no1,,Cc1ccccc1,O,Cl,c1ccncc1,test
US20040204584A1,CCNCC.COc1ccc(C2COCCO2)c2sc(NC(=O)c3ccnc(CCl)c3)nc12>>CCN(CC)Cc1cc(C(=O)Nc2nc3c(OC)ccc(C4COCCO4)c3s2)ccn1,,ClC(Cl)Cl,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040019063A1,CC(=O)Nc1ccc(C#N)c2c1CCCC2.Cl>>Cl.N#Cc1ccc(N)c2c1CCCC2,,CCO,,,,test
US08569331B2,CC(C)(C)OC(=O)NC1(c2ccc(-c3c(Br)nc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1.CCCC[Sn](CCCC)(CCCC)c1nc2ccccc2s1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4nc5ccccc5s4)nc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,C1COCCO1,O,[Cs+].[F-],,test
US20050070592A1,COC(=O)CBr.Cn1c(-c2ccccc2)c(Cc2ccccc2)c2cc(-c3ccc(O)cc3)ccc21>>COC(=O)COc1ccc(-c2ccc3c(c2)c(Cc2ccccc2)c(-c2ccccc2)n3C)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150105373A1,CCC(N)c1ccc(OC)nc1.O=C1CN(C(=O)Oc2ccc([N+](=O)[O-])cc2)c2ncccc2N1>>CCC(NC(=O)N1CC(=O)Nc2cccnc21)c1ccc(OC)nc1,,CN(C)C=O,,CCN(CC)CC,,test
US20050070592A1,CCCCCc1c(-c2ccccc2)n(C)c2ccc(-c3ccc(OCC#N)cc3)cc12.[N-]=[N+]=[N-]>>CCCCCc1c(-c2ccccc2)n(C)c2ccc(-c3ccc(OCc4nnn[nH]4)cc3)cc12,,CN(C)C=O,,[Cl-].[NH4+],,test
US05382688,CCCCC1=CCC(c2ccccc2)(c2ccccc2)CC1>>CCCCC1CCC(c2ccccc2)(c2ccccc2)CC1,O=[Pt],C1CCOC1,CC(=O)O,O,[H][H],test
US20010006969A1,C=CCN.Cc1csc2c(NC3CCCCC3)nc(Cl)nc12>>C=CCNc1nc(NC2CCCCC2)c2scc(C)c2n1.Cl,,O,,,,test
US20100305133A1,CCOC(=O)CNC(=O)c1c(O)c(Br)cc2nccnc12.OB(O)c1cncnc1>>O=C(O)CNC(=O)c1c(O)c(-c2cncnc2)cc2nccnc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20100298336A1,Cc1c(Cl)ccnc1Cl.O=C1CCC(=O)N1Br>>Clc1ccnc(Cl)c1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20050107377A1,Fc1ccc2c(-c3ccc(OCCCBr)cc3)noc2c1.NCc1ccc(Cl)c(Cl)c1>>Fc1ccc2c(-c3ccc(OCCCNCc4ccc(Cl)c(Cl)c4)cc3)noc2c1,,CC#N,,[I-].[K+],,test
US20020103229A1,NC(=O)c1ccc2c(c1)c(-c1cccc(NC(=O)c3ccco3)c1)nn2C1CCCCO1>>NC(=O)c1ccc2[nH]nc(-c3cccc(NC(=O)c4ccco4)c3)c2c1,,Cc1ccccc1,,,,test
US05093498,O=C1c2ccccc2CC1c1ccccc1>>O=C1CCc2ccccc21,,Cc1ccccc1,,[Na+].[OH-],,test
US20140045862A1,BrCc1ccccc1.O.O[C@@H]1CCC[C@@H]2O[C@@H]21>>O[C@@]1(OCc2ccccc2)CCC[C@@H]2O[C@H]21,,C1CCOC1,,[H-].[Na+],,test
US20130303524A1,CS(=O)(=O)Cl.NCc1ccco1>>CS(=O)(=O)NCc1ccco1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20040077669A1,CC#CCOc1ncnc(Cl)c1F.Oc1c(F)cccc1F>>CC#CCOc1ncnc(Oc2c(F)cccc2F)c1F,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US09273028B2,Cc1ccc(S(=O)(=O)n2ccc3c(N(CCO)[C@@H]4CCCN(C(=O)CNc5cc(Cl)cc(Cl)c5)C4)ncnc32)cc1>>O=C(CNc1cc(Cl)cc(Cl)c1)N1CCC[C@@H](N(CCO)c2ncnc3[nH]ccc23)C1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20070275962A1,NC(=O)c1c(NC(=O)C2CC2)sc2c1CCC(Br)(Br)C2=O>>NC(=O)c1c(NC(=O)C2CC2)sc2c(O)c(Br)ccc12,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US06159901,NNC(=O)c1cccc(Oc2cccc(C(F)(F)F)c2)n1.O=CC(Cl)(Cl)Cl>>O=C(NN=CC(Cl)(Cl)Cl)c1cccc(Oc2cccc(C(F)(F)F)c2)n1,,CCOC(C)=O,,c1ccccc1,,test
US20160159820A1,CN1C(C)(C)CC(O)CC1(C)C.COC(=O)c1ccc(O)c(C(F)(F)F)c1>>COC(=O)c1ccc(OC2CC(C)(C)N(C)C(C)(C)C2)c(C(F)(F)F)c1,,ClCCl,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070197542A1,CC(C)(C)OC(=O)N1CCN(c2ccc(OC(F)(F)C(F)F)cc2)CC1>>FC(F)C(F)(F)Oc1ccc(N2CCNCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04497815,COc1cc(N=C=O)cc(OC)c1OC.O=c1[nH]cc(F)c(=O)[nH]1>>COc1cc(NC(=O)n2cc(F)c(=O)[nH]c2=O)cc(OC)c1OC,,ClCCl,,c1ccncc1,,test
US04001252,CCBr.CCOC(=O)C1=C(C)NC(N)=C(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1>>CCOC(=O)C1=C(C)N=C(N)C(CC)(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1,,CCO,,C,C[O-].[Na+],test
US20130310384A1,COC(=O)c1ccc(CN([C@@H](COC(C)=O)c2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)cc1>>COC(=O)c1ccc(CN([C@@H](CO)c2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)cc1,,CO,,C[O-].[Na+],,test
US04033845,COc1cccc(C(=O)CS(C)=O)c1O.N#Cc1ccc(C=CC=O)cc1>>COc1cccc2c(=O)cc(C=Cc3ccc(C#N)cc3)oc12,,Cc1ccccc1,,C1CCNCC1,,test
US20150166480A1,CC(C)(CN1CCC(COc2ccc(Br)cn2)CC1)C(F)(F)F.COC(=O)c1ccc(B(O)O)cc1>>COC(=O)c1ccc(-c2ccc(OCC3CCN(CC(C)(C)C(F)(F)F)CC3)nc2)cc1,,O,,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US20020065308A1,COC(=O)Cc1cccc(Br)c1.OB(O)c1ccccc1>>COC(=O)Cc1cccc(-c2ccccc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20090131467A1,NN.O=C(Cc1ccc(C(F)(F)F)cc1)c1c(O)c2cccnc2n(-c2cccc(OC(F)(F)F)c2)c1=O>>O=c1c2c(Cc3ccc(C(F)(F)F)cc3)n[nH]c2c2cccnc2n1-c1cccc(OC(F)(F)F)c1,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US20070149484A1,Nc1ccc2ncc(Cl)nc2n1.OB(O)c1ccccc1>>Nc1ccc2ncc(-c3ccccc3)nc2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090131458A1,BrCC1CCCOC1.CCCCNc1nc(N)c2nc(OC)[nH]c2n1>>CCCCNc1nc(N)c2nc(OC)n(CC3CCCOC3)c2n1,,CCOC(C)=O,CN(C)C=O,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US04035372,CN(C)c1ccc(C(=O)O)cc1.c1ccc(C(c2ccccc2)C2CCNCC2)cc1>>CN(C)c1ccc(C(=O)N2CCC(C(c3ccccc3)c3ccccc3)CC2)cc1,,ClCCl,,,,test
US20130225589A1,CCc1nc(SC)ncc1C(=O)O.Cc1n[nH]c(C)c1N>>CCc1nc(SC)ncc1C(=O)Nc1c(C)n[nH]c1C,,ClCCl,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20130131018A1,CCOc1c(OC)cc(C=O)cc1OC.CCOc1cccc(CNCC(OCC)OCC)c1O.Cl>>CCOc1ccc2c(Cc3cc(OC)c(OCC)c(OC)c3)cncc2c1O.Cl,,CCO,,CO,,test
US20100137299A1,COC(=O)C1(c2ccccc2[N+](=O)[O-])C(=O)N(C)c2cc3c(cc21)OCCO3>>CN1C(=O)C2(C(=O)Nc3ccccc32)c2cc3c(cc21)OCCO3,[Pd],CO,,,,test
US05919788,CI.Cc1nc(C)c(CCO)c(=O)[nH]1>>Cc1nc(C)n(C)c(=O)c1CCO,,CO,,C[O-].[Na+],,test
US20090197864A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.CC(Oc1c([N+](=O)[O-])ncc2c(Br)coc12)c1c(Cl)ccc(F)c1Cl>>CC(Oc1c([N+](=O)[O-])ncc2c(C3=CCN(C(=O)OC(C)(C)C)CC3)coc12)c1c(Cl)ccc(F)c1Cl,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US03993674,BrC(c1ccccc1)(c1ccccc1)c1ccccc1.OC(/C=C/I)CC1CCCC1>>I/C=C/C(CC1CCCC1)OC(c1ccccc1)(c1ccccc1)c1ccccc1,,c1ccncc1,,,,test
US20020049240A1,O=C1NC(=O)C(=Cc2ccc(OCCNc3ncccn3)cc2)S1>>O=C1NC(=O)C(Cc2ccc(OCCNc3ncccn3)cc2)S1,[Pd],CN(C)C=O,,[H][H],,test
US03954793,CC#CBr.O=[N+]([O-])c1ccc2c(Cl)n[nH]c2c1>>C#CCn1nc(Cl)c2ccc([N+](=O)[O-])cc21,,CC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110046132A1,Nc1cc(Cl)c(Cl)cc1[N+](=O)[O-].O=C1CCC(=O)N1Cl>>Nc1c([N+](=O)[O-])cc(Cl)c(Cl)c1Cl,,CN(C)C=O,,,,test
US20090124612A1,CC(C)(C)OC(=O)N1CCC(N)C1.COc1ccc2c(OCc3nnc4ccc(-c5ccc(F)nc5)nn34)ccnc2c1>>COc1ccc2c(OCc3nnc4ccc(-c5ccc(NC6CCN(C(=O)OC(C)(C)C)C6)nc5)nn34)ccnc2c1,,O,,CS(C)=O,,test
US20120165331A1,COc1cc(C)nc(N2CCC(C#N)(OCCO)CC2)n1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COc1cc(C)nc(N2CCC(C#N)(OCCN=[N+]=[N-])CC2)n1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050256158A1,CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(O)cc2)c2ccccc21.CC(C)(C)OC(=O)N1CCC(CCO)CC1>>CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(OCCC3CCN(C(=O)OC(C)(C)C)CC3)cc2)c2ccccc21,,Cc1ccccc1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100240638A1,CCOC(=O)[C@H](CCCCCCCCN(C)S(=O)(=O)NC(=O)OC(C)(C)C)NS(=O)(=O)c1ccccc1[N+](=O)[O-]>>CCOC(=O)[C@H](CCCCCCCCN(C)S(N)(=O)=O)NS(=O)(=O)c1ccccc1[N+](=O)[O-],,C1COCCO1,,Cl,,test
US20080188478A1,C1CCOC1.CC(C)(C)OC(=O)N1CCC(C(=O)NN)CC1.COC(OC)N(C)C>>Cc1nnc(C2CCN(C(=O)OC(C)(C)C)CC2)o1,Cc1ccc(S(=O)(=O)O)cc1,,,,,test
US20110212918A1,CC(=O)Nc1cc(Cl)c(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)cn1>>Nc1cc(Cl)c(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)cn1,,C1CCOC1,Cl,,,test
US20080113962A1,CCCCO[C@H]1c2c(C(=O)N(C)C)cc3c(nc(C)n3C)c2N[C@H](c2ccccc2)[C@H]1O.S=C(Cl)Oc1ccccc1>>CCCCO[C@H]1c2c(C(=O)N(C)C)cc3c(nc(C)n3C)c2N[C@H](c2ccccc2)[C@H]1OC(=S)Oc1ccccc1,,ClCCl,,c1ccncc1,O=C([O-])O.[Na+],test
US20130079328A1,Cc1cc(-c2ccc(CN)cn2)ccn1.O=C(O)c1ccc(-c2cnccn2)cc1>>Cc1cc(-c2ccc(CNC(=O)c3ccc(-c4cnccn4)cc3)cn2)ccn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130338173A1,CC(C)=O.CC1(C)O[C@@H]2[C@H](O1)[C@@H](CN)C[C@H]2n1ccc2c(N)ncnc21>>CC(C)NC[C@H]1C[C@@H](n2ccc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@H]12,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100311966A1,CCCCOC(=O)c1nc(N2CC[C@H](NC(=O)OCc3ccccc3)[C@H](OC)C2)oc1C(C)C>>CCCCOC(=O)c1nc(N2CC[C@H](N)[C@H](OC)C2)oc1C(C)C,[Pd],CO,,,,test
US20120252853A1,Cc1cc2cc(C#N)ccc2n1C(F)F>>Cc1cc2cc(CN)ccc2n1C(F)F,[Ni],CO,,N,,test
US20080234335A1,OC1(c2cc(C(F)(F)F)ccc2OCc2ccccc2)CCCCC1>>FC(F)(F)c1ccc(OCc2ccccc2)c(C2=CCCCC2)c1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100311966A1,CN(C)C=C1CC(NC(=O)OC(C)(C)C)CCC1=O.NN>>CC(C)(C)OC(=O)NC1CCc2[nH]ncc2C1,,CO,,O,,test
US20050054851A1,CC(C)(C)Cn1c(Cc2ccc(N)cc2)cc2cnc(C#N)nc21.COC1CCC(OC)O1>>CC(C)(C)Cn1c(Cc2ccc(-n3cccc3)cc2)cc2cnc(C#N)nc21,,CC(=O)O,,,,test
US20100004308A1,COc1cccc2c(C3=C(c4cn(C)c5cc(I)c(F)cc45)C(=O)NC3=O)coc12.OB(O)c1ccc(Cl)cc1>>COc1cccc2c(C3=C(c4cn(C)c5cc(-c6ccc(Cl)cc6)c(F)cc45)C(=O)NC3=O)coc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20160102058A1,OC(C1CCCCC1)C1CCC(F)(F)CC1>>O=C(C1CCCCC1)C1CCC(F)(F)CC1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20110294779A1,CCOC(=O)c1cnn(CC)c1C(=O)Nc1ccn2cc(-c3ccccc3)nc2c1>>CCn1ncc(C(=O)O)c1C(=O)Nc1ccn2cc(-c3ccccc3)nc2c1,,CCO,,[K+].[OH-],,test
US05885986,CCCN(CCC)Cc1cnc(-c2ncn3c2CN(C)C(=O)c2c(Cl)cccc2-3)o1.Cl>>CCCN(CCC)Cc1cnc(-c2ncn3c2CN(C)C(=O)c2c(Cl)cccc2-3)o1.Cl,,CCOC(C)=O,,,,test
US20110306587A1,O=C(c1nc2ccccc2[nH]1)N1CC(c2nccnc2Cl)C1.OC1CCNCC1>>O=C(c1nc2ccccc2[nH]1)N1CC(c2nccnc2N2CCC(O)CC2)C1,,O,,CCN(CC)CC,CS(C)=O,test
US20120282218A1,Fc1ccccc1CBr.O=c1[nH]cc(Cc2ccc(F)cc2F)cc1I>>O=c1c(I)cc(Cc2ccc(F)cc2F)cn1Cc1ccccc1F,,CN(C)C=O,,[H-].[Na+],,test
US20130116243A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)C(=O)NCC4)cc2)CCC1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)C(=S)NCC4)cc2)CCC1,,Cc1ccccc1,,,,test
US20090318475A1,CCCCC(C(=O)OC)N(C)c1ncnc2oc(-c3ccccc3)c(Br)c12.COc1ccc(B(O)O)cc1>>COC(=O)CCCCCN(C)c1ncnc2oc(-c3ccccc3)c(-c3ccc(OC)cc3)c12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CO,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US04061647,CC(=O)c1cc([N+](=O)[O-])c(Cl)cc1Cl>>CC(=O)c1cc(N)c(Cl)cc1Cl,[Fe],CCO,,Cl,,test
US20080161306A1,CCOC(=O)c1cccc([C@@H]2CC[C@@H](N=[N+]=[N-])CC2)c1>>CCOC(=O)c1cccc([C@@H]2CC[C@@H](N)CC2)c1,[Pd],CCO,,CC(=O)O,,test
US20090306373A1,CC(C)(C)OC(=O)NCCO.CCC(=O)C1C(=O)OC(C)(C)OC1=O>>CCC(=O)CC(=O)OCCNC(=O)OC(C)(C)C,,Cc1ccccc1,,,,test
US04898863,COC(=O)C=Cc1cn(Cc2ccc(C(=O)OC(C)(C)C)cc2OC)c2cc(C(=O)NCC3CCCC3)ccc12>>COC(=O)CCc1cn(Cc2ccc(C(=O)OC(C)(C)C)cc2OC)c2cc(C(=O)NCC3CCCC3)ccc12,[Pd],CO,,[H][H],,test
US20050272778A1,CS(=O)(=O)c1ccc(-c2ccc(CO)cc2)cc1.C[Si](C)(C)Br>>CS(=O)(=O)c1ccc(-c2ccc(CBr)cc2)cc1,,C1COCCO1,,,,test
US20160207905A1,CCOC(=O)C=C1CCCC1>>O=C(O)C=C1CCCC1,,CO,,Cl,[K+].[OH-],test
US04923857,C=CCOC(=O)N1C[C@H](O)C[C@H]1C(=O)OC.CS(=O)(=O)Cl>>C=CCOC(=O)N1C[C@H](OS(C)(=O)=O)C[C@H]1C(=O)OC,,ClCCl,,CCN(CC)CC,,test
US04118742,CC(C)C(O)(c1ccccc1)c1ccc2nc(N)n(S(=O)(=O)N(C)C)c2c1>>CC(C)=C(c1ccccc1)c1ccc2nc(N)n(S(=O)(=O)N(C)C)c2c1,,ClC(Cl)Cl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20160243100A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.Cn1nc(C2CC2)cc1O>>Cn1nc(C2CC2)cc1S,,Cc1ccccc1,,,,test
US20140011795A1,CC1(C)[C@H](N)CC[C@@]1(C)O.NC(=O)c1cnn2cc(Br)cc2c1Cl>>CC1(C)[C@H](Nc2c(C(N)=O)cnn3cc(Br)cc23)CC[C@@]1(C)O,,CC#N,,CCN(C(C)C)C(C)C,,test
US04542142,CC1(C)[C@@H](/C=C\C(=O)O)[C@H]1C(=O)O[C@H](C#N)c1cccc(Oc2ccccc2)c1.N#CC(O)C(Cl)(Cl)Cl>>CC1(C)[C@@H](/C=C\C(=O)OC(C#N)=C(Cl)Cl)[C@H]1C(=O)O[C@H](C#N)c1cccc(Oc2ccccc2)c1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04088767,CCOC(=O)Cl.O=c1[nH][nH]c(=O)n1-c1cc(Cl)cc(Cl)c1>>CCOC(=O)n1[nH]c(=O)n(-c2cc(Cl)cc(Cl)c2)c1=O,,CN(C)C=O,,CCN(CC)CC,O,test
US20110021434A1,COC(=O)[C@@H]1CC=CCOc2ccc(cc2)C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C(C)C)C(=O)N1>>COC(=O)[C@@H]1CCCCOc2ccc(cc2)C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C(C)C)C(=O)N1,[Pd],CCOC(C)=O,,,,test
US20150315222A1,Cc1cc(B2OC(C)(C)C(C)(C)O2)c2oc3nc(C)ccc3c2c1.Clc1ccc2c(Cl)nccc2c1>>Cc1cc(-c2nccc3cc(Cl)ccc23)c2oc3nc(C)ccc3c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20020193382A1,C[S+](C)(C)=O.O=C1CCN(c2cc(Cl)ncn2)CC1>>Clc1cc(N2CCC3(CC2)CO3)ncn1,,CS(C)=O,,[H-].[Na+],,test
US20150087585A1,CCO.N#Cc1cncc(C2CC2)n1>>CCOC(=N)c1cncc(C2CC2)n1,,CCO,,C,C[O-].[Na+],test
US20150284418A1,Cc1cc2c(c(C)c1O)CC(C)C2=O>>CC1=Cc2cc(C)c(O)c(C)c2C1,,C1CCOC1,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20130079478A1,C1CCC(NC2CCCCC2)CC1.CNCC(C)C.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)CN(C)C(=O)N(C1CCCCC1)C1CCCCC1,,C1CCOC1,,CCN(CC)CC,,test
US20080207654A1,CC(C)(C)CI.CCCc1nc(CC)c(-c2ccc(O)cc2)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1>>CCCc1nc(CC)c(-c2ccc(OCC(C)(C)C)cc2)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US05334225,Cc1ccc(NC(=O)CCNC(=O)OC(C)(C)C)c(O)c1.Cl>>Cc1ccc(NC(=O)CCN)c(O)c1.Cl,,CCOCC,,CC(C)=O,,test
US20090221555A1,COc1ccc2c(c1N)CN(Cc1ccccc1)CC(=O)N2.CS(=O)(=O)N[C@@H]1CCCC[C@H]1Nc1nc(Cl)ncc1Cl>>COc1ccc2c(c1Nc1ncc(Cl)c(N[C@@H]3CCCC[C@H]3NS(C)(=O)=O)n1)CN(Cc1ccccc1)CC(=O)N2,,COCCO,,C1COCCO1,Cl,test
US04874781,C=C(C(C(=O)OCC)c1ccc(Cl)cc1)C(F)(F)F>>C=C(C(C(=O)O)c1ccc(Cl)cc1)C(F)(F)F,,O,,[Na+].[OH-],,test
US20110166122A1,CC(=O)OC(C)=O.Nc1cnc2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nn12>>CC(=O)Nc1cnc2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nn12,,ClCCl,,c1ccncc1,,test
US20090048239A1,CC(C)[Si](Cl)(C(C)C)C(C)C.COc1ccc(Br)c(CO)c1>>COc1ccc(Br)c(CO[Si](C(C)C)(C(C)C)C(C)C)c1,,CN(C)C=O,,c1c[nH]cn1,,test
US05538939,CC(C)CC(=O)Cl.CC(C)c1noc(N)c1C(N)=O>>CC(C)CC(=O)Nc1onc(C(C)C)c1C(N)=O,,Cc1ccccc1,c1ccncc1,CN(C)c1ccccn1,,test
US06936602B1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3c2ccc(OC)cc2)cc1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3c2ccc(OC)cc2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US05126482,C=C[C@H](O)CCCCC.O=C(Cl)C(F)C(F)(F)F>>C=CC(CCCCC)OC(=O)C(F)C(F)(F)F,,ClCCl,,O,c1ccncc1,test
US20090143358A1,COC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(OC)cc2OC)c2ncc(Cl)s2)cc1F>>COC(=O)c1ccc(S(=O)(=O)Nc2ncc(Cl)s2)cc1F,,C1COCCO1,,Cl,,test
US20090111820A1,CCOC(=O)[C@H]1C[C@H]2C[C@H]2N1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1[C@@H](C(=O)O)C[C@H]2C[C@H]21,,CCO,O,[Li+].[OH-],,test
US20120108585A1,COC(=O)c1cccc(N)c1O.O=C(Cl)c1cccc(C(F)(F)F)c1>>COC(=O)c1cccc(NC(=O)c2cccc(C(F)(F)F)c2)c1O,,CCOC(C)=O,c1ccncc1,,,test
US20130217664A1,CN(C(=O)OC(C)(C)C)c1cc2c(cn1)ncn2C>>CNc1cc2c(cn1)ncn2C,,CO,,C1COCCO1,Cl,test
US20050197338A1,COc1ccc(CNC(=O)c2n[nH]cc2NC(N)=O)cc1.Ic1ccccn1>>COc1ccc(CNC(=O)c2nn(-c3ccccn3)cc2NC(N)=O)cc1,[Cu]I,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060148857A1,NC1CCCc2c1[nH]c1ccc(Br)cc21.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)NC1CCCc2c1[nH]c1ccc(Br)cc21,,ClCCl,,,,test
US20050143588A1,CC(=O)Oc1ccc(C2COc3c(ccc(OC(C)=O)c3C)C2O)cc1>>Cc1c(O)ccc2c1OCC(c1ccc(O)cc1)C2O,,CCO,,c1c[nH]cn1,,test
US20160264567A1,C[C@H]1[C@H](F)C[C@@H](C(=O)O)N1C(=O)OC(C)(C)C.NCc1cc(-c2cnc(C(F)(F)F)nc2)ncc1F>>C[C@H]1[C@H](F)C[C@@H](C(=O)NCc2cc(-c3cnc(C(F)(F)F)nc3)ncc2F)N1C(=O)OC(C)(C)C,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060217387A1,ClI.FC(F)(F)c1ccc(-c2cc(C(F)(F)F)n3nccc3n2)cc1>>FC(F)(F)c1ccc(-c2cc(C(F)(F)F)n3ncc(I)c3n2)cc1,,CC(=O)O,O,CC(=O)[O-].[Na+],,test
US20130046004A1,Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(OCC(=O)C(C)(C)C)n(-c2ccccc2F)n1>>Cc1ccccc1[C@H](CC(=O)O)NC(=O)c1cc(OCC(O)C(C)(C)C)n(-c2ccccc2F)n1,,ClCCl,,[BH4-].[Na+],,test
US04873236,CCN(CC)CC1CCCCN1CCCN.O=C1Nc2ccccc2N(C(=O)Cl)c2ccccc21>>CCN(CC)CC1CCCCN1CCCNC(=O)N1c2ccccc2NC(=O)c2ccccc21,,O,,CC(C)OC(C)C,,test
US05859257,Cc1noc(-c2ccccc2)c1-c1ccc(S(N)(=O)=O)cc1.O=Cc1ccc(Cl)cc1>>NS(=O)(=O)c1ccc(-c2c(CC(O)c3ccc(Cl)cc3)noc2-c2ccccc2)cc1,,C1CCOC1,O,CN(C)CCN(C)C,[Li]CCCC,test
US20100216814A1,Cc1ccc2c(c1)c1c(n2C#C[Si](C(C)C)(C(C)C)C(C)C)CCN(C)C1>>C#Cn1c2c(c3cc(C)ccc31)CN(C)CC2,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20050256158A1,C=Cc1ccc(C(=O)OC)cc1F>>CCc1ccc(C(=O)OC)cc1F,[Pd],CCO,,,,test
US20030236212A1,CC(C)(CO)CCCCC(CCCCC(C)(C)CO)C(=O)O.[Li]C>>CC(=O)C(CCCCC(C)(C)CO)CCCCC(C)(C)CO,,C1CCOC1,,Cl,,test
US20060122399A1,C1COCCN1.CCc1cc(Br)ccc1CBr>>CCc1cc(Br)ccc1CN1CCOCC1,,CC#N,,CCN(CC)CC,,test
US20070123560A1,CC(C)(C)OC(=O)NC1([C@@H]2CCNC2)CC1.COc1c(F)cc(N)c2c(=O)c(C(=O)O)cn([C@@H]3C[C@@H]3F)c12>>COc1c(N2CC[C@@H](C3(N)CC3)C2)cc(N)c2c(=O)c(C(=O)O)cn([C@@H]3C[C@@H]3F)c12,,ClC(Cl)Cl,,CCN(CC)CC,CS(C)=O,test
US20160002204A1,NCc1ccccn1.O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccn(CCCCn2cc(C(=O)O)nn2)c(=O)c1>>O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccn(CCCCn2cc(C(=O)NCc3ccccn3)nn2)c(=O)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04443443,CCOC(=O)N1CCN(CCCN2C(=O)c3ccccc3C2=O)CC1>>CCOC(=O)N1CCN(CCCN)CC1,,CCO,,NN,O,test
US20080015199A1,COC(=O)N=C(SC)C(=Nc1ccc(-c2noc(C)n2)cc1)c1cc(OC)cc(O)c1F.FCCI>>COC(=O)N=C(SC)C(=Nc1ccc(-c2noc(C)n2)cc1)c1cc(OC)cc(OCCF)c1F,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US06140351,COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cc2)c1NC(=O)c1scc(CCl)c1Cl.C[S-]>>CSCc1csc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cc2)c1Cl,,CN(C)C=O,,O,,test
US20090176778A1,NCc1cccs1.O=C(O)c1nc2c(C(F)(F)F)cc(Br)cn2c1Cl>>O=C(NCc1cccs1)c1nc2c(C(F)(F)F)cc(Br)cn2c1Cl,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20150175594A1,O=C(O)C1=C(C(=O)Nc2sc3c(c2-c2nc(C(F)(F)F)no2)CCCCC3)CCC1.O=C1OC(=O)C2=C1CCCC2>>O=C(O)C1=C(C(=O)Nc2sc3c(c2-c2nc(C(F)(F)F)no2)CCCCC3)CCCC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20050054638A1,N#Cc1cncc(-c2ccccn2)c1>>NCc1cncc(-c2ccccn2)c1,[Pd],CCO,CO,Cl,,test
US04886805,Cc1ccc(S(=O)(=O)N2CCN(CCSc3nnc4ccccn34)CC2)cc1>>c1ccn2c(SCCN3CCNCC3)nnc2c1,,Cl,,[Na+].[OH-],,test
US20090306141A1,CCOC(=O)c1[nH]c(C)cc1C>>Cc1cc(C)c(C(=O)O)[nH]1,,C1CCOC1,,CO,[Na+].[OH-],test
US06174874B1,CC(C)(C)OP(=O)(OC(C)(C)C)C(F)(F)c1ccc(CC(Cc2ccc(C(F)(F)P(=O)(OC(C)(C)C)OC(C)(C)C)cc2)(C(=O)OCc2ccccc2)C(=O)OCc2ccccc2)cc1>>O=C(OCc1ccccc1)C(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)(Cc1ccc(C(F)(F)P(=O)(O)O)cc1)C(=O)OCc1ccccc1,,O,O=C(O)C(F)(F)F,,,test
US05545755,C=CCBr.O=C1CCc2ccccc2C1>>C=CCC1C(=O)CCc2ccccc21,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20090111805A1,OC(c1ccccc1)c1c[nH]c2ncnc(Cl)c12>>Clc1ncnc2[nH]cc(Cc3ccccc3)c12,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20120071461A1,CC(C)(C)OC(=O)N1CCc2nc(S(C)(=O)=O)ncc2C1.CNC>>CN(C)c1ncc2c(n1)CCN(C(=O)OC(C)(C)C)C2,,CN1CCCC1=O,O,CCN(C(C)C)C(C)C,Cl,test
US20100144722A1,CC(C)(C)N.Clc1cc(Cl)nc(Cl)n1>>CC(C)(C)Nc1cc(Cl)nc(Cl)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110224204A1,ClCc1ccc2ccccc2n1.O=[N+]([O-])c1cccc(-c2ccncc2)c1-c1ccc(O)cc1>>O=[N+]([O-])c1cccc(-c2ccncc2)c1-c1ccc(OCc2ccc3ccccc3n2)cc1,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US06107329,NC(Cc1ccccc1)C(=O)N1CC(O)C1.O=C(O)c1cc2cc(Cl)ccc2[nH]1>>O=C(N[C@@H](Cc1ccccc1)C(=O)N1CC(O)C1)c1cc2cc(Cl)ccc2[nH]1,,CN(C)C=O,ClCCl,Cl,,test
US20050245553A1,COC(C#N)C(N(C)C)N(C)C.N=C(N)c1nn(Cc2ccccc2F)c2ncccc12>>COc1cnc(-c2nn(Cc3ccccc3F)c3ncccc23)nc1N,,CC(C)CCO,,C1CCNCC1,,test
US05650415,CCOC(=O)c1cnc2ccc(C(F)(F)F)cc2c1Cl.Nc1cccc(Br)c1>>CCOC(=O)c1cnc2ccc(C(F)(F)F)cc2c1Nc1cccc(Br)c1,,CCO,,[Na+].[OH-],,test
US20140155381A1,CCOC(=O)Cc1ccc(O)cn1.II>>CCOC(=O)Cc1ccc(O)c(I)n1,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20060100213A1,C#CC[C@H]1Nc2cccnc2NC1=O.Cc1ccc(S(=O)(=O)Cl)cc1>>C#CC[C@@H]1C(=O)Nc2ncccc2N1S(=O)(=O)c1ccc(C)cc1,,c1ccncc1,,Cl,,test
US20130150364A1,Cc1ccc2nc(C(F)F)n(-c3cc(N4CCOC[C@@H]4C)nc(NC[C@@H]4CC[C@@H](NCC(C)(C)O)CC4)n3)c2c1.O=C(n1ccnc1)n1ccnc1>>Cc1ccc2nc(C(F)F)n(-c3cc(N4CCOC[C@@H]4C)nc(NC[C@@H]4CC[C@@H](N5CC(C)(C)OC5=O)CC4)n3)c2c1,,C1CCOC1,,CCN(CC)CC,O,test
US20130059849A1,CCOC(=O)C(=O)/C=C(\O)C1CC1.Cc1cc(N)n(C2CCOCC2)n1>>CCOC(=O)c1cc(C2CC2)nc2c1c(C)nn2C1CCOCC1,,CC(=O)O,,,,test
US20050209338A1,CC1(C)OCc2cc([C@@H](O)CNCCCCCCOCCC#Cc3cccc(NC(=O)Nc4cccnc4)c3)ccc2O1>>CC1(C)OCc2cc([C@@H](O)CNCCCCCCOCCCCc3cccc(NC(=O)Nc4cccnc4)c3)ccc2O1,[Pd],CCO,,CCOC(C)=O,,test
US07285136B2,NCc1ccccc1.O=[N+]([O-])c1c(Br)nn(CCCO)c1Br>>O=[N+]([O-])c1c(Br)nn(CCCO)c1NCc1ccccc1,,CCO,,,,test
US20030095958A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C1CNCCc2c1[nH]c1ccccc21>>COC(=O)C1CN(C(=O)OC(C)(C)C)CCc2c1[nH]c1ccccc21,,CO,,CCN(CC)CC,,test
US04680299,CCC(=O)c1ccc(-c2ccccc2F)cc1.O=C1Nc2ccc(F)cc2C1=O>>Cc1c(-c2ccc(-c3ccccc3F)cc2)nc2ccc(F)cc2c1C(=O)O,,CCO,O,[K+].[OH-],,test
US20160106731A1,CCOC(=O)Cc1c(C(=O)OC)n2c3c(cccc13)SCC2>>COC(=O)c1c(CCO)c2cccc3c2n1CCS3,,C1CCOC1,,,,test
US04851422,COC(=O)C1(Cl)C=CC(=O)O1.O=C(Cc1ccccc1)N[C@@H]1CONC1=O>>COC(=O)C1(N2OC[C@@H](NC(=O)Cc3ccccc3)C2=O)C=CC(=O)O1,,ClCCl,,CCN(CC)CC,,test
US20100210624A1,CN1CCC(Oc2ccccc2)c2ccc(-c3cccnn3)cc2C1.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>CN1CCC(Oc2ccccc2)c2ccc(-c3cccnn3)cc2C1.O=C(O)C(O)C(O)C(=O)O,,CO,,O,,test
US20140213586A1,COc1cc(NC(C(=O)c2c[nH]c3ccccc23)c2ccc(F)cc2)cc(OCCOC(C)(C)C)c1>>COc1cc(NC(C(=O)c2c[nH]c3ccccc23)c2ccc(F)cc2)cc(OCCO)c1,,Cl,,C1COCCO1,,test
US20130324514A1,Cc1cc(OCC2CN(C(=O)OC(C)(C)C)C2)cc(C)c1Br>>Cc1cc(OCC2CNC2)cc(C)c1Br,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20120178752A1,COC(=O)c1cccc(O[C@@H]2CCN(c3ccc(C#N)cc3)C2=O)c1>>N#Cc1ccc(N2CC[C@@H](Oc3cccc(C(=O)O)c3)C2=O)cc1,,C1CCOC1,,O,[Li+].[OH-],test
US20100093865A1,CCCC(CCC)NS(=O)(=O)c1cccc(CCCNC(=O)OC(C)(C)C)c1.Cl>>CCCC(CCC)NS(=O)(=O)c1cccc(CCCN)c1.Cl,,C1COCCO1,Cl,ClCCl,,test
US20110092547A1,CCOC(=O)C1CCC(Oc2ccc(NC(=O)C(=O)NN)cn2)CC1.FC(F)Oc1ccc(N=C=S)cc1>>CCOC(=O)C1CCC(Oc2ccc(NC(=O)c3nnc(Nc4ccc(OC(F)F)cc4)o3)cn2)CC1,,CN(C)C=O,,CCN=C=NCCCN(C)C,Cl,test
US20070037836A1,CN(C)c1nc(NC[C@@H]2CC[C@@H](CN)CC2)nc2ccccc12.O=Cc1ccc(Br)cc1OC(F)(F)F>>CN(C)c1nc(NC[C@@H]2CC[C@@H](CNCc3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20110224252A1,Nc1ncc(Cl)cc1Cl.O=Cc1ccc(Br)cc1>>Clc1cnc(/N=C/c2ccc(Br)cc2)c(Cl)c1,,Cc1ccccc1,,,,test
US20100261698A1,CCS(=O)(=O)Nc1cncc(-c2cc3ccccc3n2C)c1.CI>>CCS(=O)(=O)N(C)c1cncc(-c2cc3ccccc3n2C)c1,,CN(C)C=O,,[H-].[Na+],,test
US20110263593A1,Brc1cnc2nccn2c1.NC1CCCCC1>>c1cn2cc(NC3CCCCC3)cnc2n1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080269213A1,BrCc1ccccc1.C=CCc1ccc2cccnc2c1O>>C=CCc1ccc2cccnc2c1OCc1ccccc1,,CC(C)=O,CCOCC,O=C([O-])[O-].[K+].[K+],,test
US20040009995A1,CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2NC(=O)NCCNC(=O)NCC(=O)O)c1.O=C(O)C(F)(F)F>>CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2NC(=O)NCCNC(=O)NCC(=O)O)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20130245006A1,CCCCc1cc2cc(C(=O)OC(C)C)ccn2c1.O=C(Cl)c1ccc(CCCCl)cc1>>CCCCc1cc2cc(C(=O)OC(C)C)ccn2c1C(=O)c1ccc(CCCCl)cc1,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20040198711A1,C[C@]12CC[C@@H]3c4ccc(OCc5ccccc5)cc4CC[C@H]3[C@@H]1[C@@H](C(C(=O)O)C(=O)O)CC2=O>>C[C@]12CC[C@@H]3c4ccc(OCc5ccccc5)cc4CC[C@H]3[C@@H]1[C@@H](CC(=O)O)CC2=O,,COCCOCCOC,,O,,test
US20080009491A1,O=C(OC(=O)C(F)(F)F)C(F)(F)F.c1ccn2c(CCN3CCOCC3)ncc2c1>>O=C(c1nc(CCN2CCOCC2)n2ccccc12)C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070299050A1,COC(=O)c1cc(C)c2c(c1)S(=O)(=O)Cc1cc(NC(=O)CCl)cc(Cl)c1O2.COC(=O)c1cc(C)c2c(c1)S(=O)(=O)Cc1cc(NC(=O)COC(C)=O)cc(Cl)c1O2.O>>COC(=O)c1cc(C)c2c(c1)S(=O)(=O)Cc1cc(NC(=O)CO)cc(Cl)c1O2.COC(=O)c1cc(C)c2c(c1)S(=O)(=O)Cc1cc(NC(=O)COC(C)=O)cc(Cl)c1O2,,CN(C)C=O,O,,,test
US20040058978A1,CCOC(=O)CNC(=O)c1cccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)c1>>O=C(O)CNC(=O)c1cccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)c1,,CCO,,[Na+].[OH-],,test
US04638067,CC(C)(C)OC(=O)NCC1CCN1.CCn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)nc21>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCC3CN)nc21,,CC#N,,CCN(CC)CC,,test
US20140371199A1,CNc1ccncc1.N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)O)cc4)cn23)cc1>>CN(C(=O)c1ccc(-c2ccc3ncc(-c4ccc(C#N)cc4)n3c2)cc1)c1ccncc1,,CN(C)C=O,O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070244087A1,CC(C)(C)OC(=O)NC1CSCCNC1=O.CCCCOc1ccc(CBr)cc1>>CCCCOc1ccc(CN2CCSCC(NC(=O)OC(C)(C)C)C2=O)cc1,,CCOC(C)=O,O,C1CCOC1,[H-].[Na+],test
US05807859,CC(=O)Nc1ccc(CC2c3ccccc3-c3[nH]c(=O)c4nccn4c32)cc1>>Nc1ccc(CC2c3ccccc3-c3[nH]c(=O)c4nccn4c32)cc1,,CC(=O)O,,O,[Na+].[OH-],test
US20040167224A1,CC(C)(C)OCC(N)C(N)=O.O=S(Cl)Cl>>CC(C)(C)OCc1nsnc1O,,CCN(CC)CC,ClCCl,O,,test
US20020068737A1,C[Si](C)(C)C#N.N.O=Cc1ccc(F)c(F)c1>>N#CC(N)c1ccc(F)c(F)c1,,CO,,CCCCCC,CCOC(C)=O,test
US20090137561A1,COc1ccc(F)c(-c2ccc(CO[Si](C)(C)C(C)(C)C)cc2C(O)(C(C)C)C(C)C)c1.O=S(Cl)Cl>>COc1ccc(F)c(-c2ccc(CCl)cc2C(O)(C(C)C)C(C)C)c1,,ClCCl,,CN(C)C=O,,test
US20050288337A1,CCOC(=O)CCc1ccc(Cn2cccc(-c3ccc(N)cc3)c2=O)cc1.Cc1ccccc1N=C=O>>CCOC(=O)CCc1ccc(Cn2cccc(-c3ccc(NC(=O)Nc4ccccc4C)cc3)c2=O)cc1,,ClCCl,,,,test
US20120208844A1,C1CCOC1.CCOCC.COc1ccncc1.O=C(Cl)OCc1ccccc1>>C=CCC1CC(=O)C=CN1C(=O)OCc1ccccc1,,CCOCC,,Cl,,test
US20160122335A1,C[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3cc(C(C)(C)O)on3)nc2C(=O)O)c(Cl)c1Cl)C(F)(F)F.FC1(F)CCNCC1>>C[C@H](NS(=O)(=O)c1ccc(-c2sc(-c3cc(C(C)(C)O)on3)nc2C(=O)N2CCC(F)(F)CC2)c(Cl)c1Cl)C(F)(F)F,,CC(=O)N(C)C,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20110172209A1,CS(=O)(=O)Oc1ccc(N)c(NC2CCCCC2)n1.O=C(n1ccnc1)n1ccnc1>>CS(=O)(=O)Oc1ccc2nc(O)n(C3CCCCC3)c2n1,,C1CCOC1,,,,test
US04035499,COc1ccc(C(=O)C(Br)c2ccc(OC)cc2)cc1.c1ccc2cnccc2c1>>COc1ccc(C(=O)C(c2ccc(OC)cc2)c2[nH+]ccc3ccccc23)cc1.[Br-],,ClC(Cl)Cl,,CCOCC,,test
US20110152287A1,CC(C)(C)OC(=O)N[C@@H](Cc1cccs1)C(=O)N1CCN(c2nc3ccc(CNC4CCCC4)cc3s2)CC1>>N[C@@H](Cc1cccs1)C(=O)N1CCN(c2nc3ccc(CNC4CCCC4)cc3s2)CC1,,C1COCCO1,Cl,CCOCC,,test
US20140213578A1,[N-]=[N+]=NC[C@@H](O)CN1c2ccccc2CCc2ccccc21>>NC[C@@H](O)CN1c2ccccc2CCc2ccccc21,O,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060128633A1,COc1cc2c(c(OC)c1OC)-c1ccc(OC(=O)CCNC(=O)[C@@H](CCCCNC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)cc1[C@@H](NC(C)=O)CC2>>COc1cc2c(c(OC)c1OC)-c1ccc(OC(=O)CCNC(=O)[C@H](N)CCCCN)cc1[C@@H](NC(C)=O)CC2,,ClCCl,,CCOCC,Cl,test
US20050245518A1,CN=C=S.CNc1ccc([N+](=O)[O-])cc1N>>CNc1nc2cc([N+](=O)[O-])ccc2n1C,,c1ccncc1,,ClCCCl,,test
US20090163512A1,CCOC(=O)C(C)(C)Oc1ccc(F)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12>>Cc1ccc(F)cc1C1NC(=O)CC(c2cc(F)ccc2OC(C)(C)C(=O)O)C12C(=O)Nc1cc(Cl)ccc12,,C1CCOC1,,O,[Na+].[OH-],test
US20070281918A1,CC1CN(C(=O)C(F)(F)F)CCc2nc(O)c(I)cc21>>CC1CNCCc2nc(O)c(I)cc21,,CO,,O=C([O-])[O-].[K+].[K+],,test
US05710162,O=C(O)c1c(-c2ccc3c(c2)OCO3)c2ccccc2[nH]c1=O.O=P(Cl)(Cl)Cl>>O=C1c2cc3c(cc2-c2c1c(Cl)nc1ccccc21)OCO3,,C1CCOC1,,,,test
US20030220241A1,N#Cc1ccc(Cn2cncc2CN2CCN(c3cccc4ccc(OCc5ccccc5)cc34)C(=O)C2)cc1F.O=C(O)C(F)(F)F>>N#Cc1ccc(Cn2cncc2CN2CCN(c3cccc4ccc(O)cc34)C(=O)C2)cc1F.O=C(O)C(F)(F)F,[Pd],CCOC(C)=O,CO,[H][H],,test
US20040110757A1,COC(=O)c1cccc(C(=O)Nc2ccc(-c3cc(-c4ccc(NC(=O)c5cccc(C(=O)OC)c5)cc4)nc(-c4ccccc4)n3)cc2)c1>>O=C(O)c1cccc(C(=O)Nc2ccc(-c3cc(-c4ccc(NC(=O)c5cccc(C(=O)O)c5)cc4)nc(-c4ccccc4)n3)cc2)c1,,C1CCOC1,CO,Cl,[K+].[OH-],test
US20110306607A1,COC(=O)c1ccccc1C(=O)N1CCC2(CC1)Oc1ccccc1-c1c2cnn1C>>Cn1ncc2c1-c1ccccc1OC21CCN(C(=O)c2ccccc2C(=O)O)CC1,,C1COCCO1,,[Na+].[OH-],,test
US05026700,COC(=O)CCSc1cc(C(=O)OC)nc2ccccc12>>O=C(O)CCSc1cc(C(=O)O)nc2ccccc12,,CO,,[Li+].[OH-],,test
US05021443,CCOC(=O)CC(C)(C)Cc1nc2ccccc2n1Cc1ccccc1>>CC(C)(CC(=O)O)Cc1nc2ccccc2n1Cc1ccccc1,,CC(=O)O,,Cl,O,test
US05272163,Cc1cccc(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)c1>>Cc1cccc(S(=O)(=O)c2ccc(N)cc2)c1,,CCO,,[Na+].[OH-],,test
US20090286783A1,CCCS(=O)(=O)Nc1cccc(C=O)c1F.c1ncc2cc[nH]c2n1>>CCCS(=O)(=O)Nc1cccc(C(O)c2c[nH]c3ncncc23)c1F,,CO,,O,[K+].[OH-],test
US04088695,CCCCC(C)C(=O)CCl.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CCCCC(C)C(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1,,ClC(Cl)Cl,,,,test
US20040209857A1,C1COCCN1.COc1cc(CC(=O)OCc2ccccc2)c(S(=O)(=O)Cl)cc1OC>>COc1cc(CC(=O)OCc2ccccc2)c(S(=O)(=O)N2CCOCC2)cc1OC,,C1CCOC1,,CCN(CC)CC,O,test
US20130023541A1,CCN[C@H]1CCN(c2ncccc2C(=O)OC(C)C)C1.Cc1cc(C=O)sc1C>>CCN(Cc1cc(C)c(C)s1)[C@H]1CCN(c2ncccc2C(=O)OC(C)C)C1,,C1CCOC1,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130225580A1,CC1(C)CCc2cc(S(=O)(=O)Cl)ccc2O1.Cc1cc(N)n(-c2cccc3ncccc23)n1>>Cc1cc(NS(=O)(=O)c2ccc3c(c2)CCC(C)(C)O3)n(-c2cccc3ncccc23)n1,,c1ccncc1,,ClCCl,,test
US20070293530A1,C=O.O=C(O)CCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)O>>O=C(O)CCCCC[C@H]1C(=O)OCN1C(=O)OCc1ccccc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20030069421A1,O=C1Cc2ccccc2N1.O=Cc1ccc(N2CCN(C=O)CC2)cc1>>O=CN1CCN(c2ccc(/C=C3/C(=O)Nc4ccccc43)cc2)CC1,C1CCNCC1,CCO,,,,test
US20100256156A1,Br[Mg]C1CCCCC1.Cc1sc(-c2ccc(C(F)(F)F)cc2)cc1C=O>>Cc1sc(-c2ccc(C(F)(F)F)cc2)cc1C(O)C1CCCCC1,,C1CCOC1,,Cl,,test
US04988686,CC(C)N.O=C1C=C(CO)N=CC1OC(c1ccccc1)c1ccccc1>>CC(C)n1cc(OC(c2ccccc2)c2ccccc2)c(=O)cc1CO,,CO,,ClC(Cl)Cl,,test
US09000186B2,CC(C)CO.CCN(CC)C(=O)c1ccn2c(S(=O)(=O)C3CCCCC3)c(C(C)C)nc2c1>>CC(C)c1nc2cc(C(=O)O)ccn2c1S(=O)(=O)C1CCCCC1,,CC(C)CO,,CCOCC,[Na+].[OH-],test
US20110003787A1,COC[C@H](C)Oc1cc(Oc2ccc(C(=O)NNC(C)=O)cc2F)cc(-c2ccc(-c3nccs3)[nH]2)c1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COC[C@H](C)Oc1cc(Oc2ccc(-c3nnc(C)s3)cc2F)cc(-c2ccc(-c3nccs3)[nH]2)c1,,CC#N,Cc1ccccc1,c1ccncc1,,test
US04665090,CCOC(=O)N1C(=O)c2ccccc2C1=O.NCCc1cccs1>>O=C1c2ccccc2C(=O)N1CCc1cccs1,,CCO,,,,test
US20150065464A1,Cc1cc(CO)cc(Oc2ccc(C(F)(F)F)cn2)c1.O=S(Cl)Cl>>Cc1cc(CCl)cc(Oc2ccc(C(F)(F)F)cn2)c1,,ClCCl,,,,test
US20100103366A1,C=C(C)C(=O)O.CCCC1CCC(C(=O)OCCCCBr)CC1>>C=C(C)C(=O)OCCCCOC(=O)C1CCC(CCC)CC1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080085890A1,CO/C=C1/C(=O)NC(=O)c2ccccc21.Nc1cccc(CN2CCCCCC2)c1>>O=C1NC(=O)c2ccccc2/C1=C/Nc1cccc(CN2CCCCCC2)c1,,CCCCCC,,CN(C)C=O,,test
US20120329818A1,CC(C)(C)OC(=O)N1CCC(C)(C(=O)O)CC1.Nc1cccc(-c2cnco2)c1>>CC(C)(C)OC(=O)N1CCC(C)(C(=O)Nc2cccc(-c3cnco3)c2)CC1,CN(C)C=O,CCOC(C)=O,ClCCCl,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20130053397A1,CCN.Cc1cc(Cl)c(C#N)c(=O)[nH]1>>CCNc1cc(C)[nH]c(=O)c1C#N,,CO,,Cl,,test
US04179505,CNc1ccc(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1N.NC(N)=O>>Cn1c(=O)[nH]c2cc(CN3CCN(C(c4ccccc4)c4ccccc4)CC3)ccc21,,Cl,O,C,,test
US20150148340A1,CCOC=C(C(=O)NC(=O)OCC)C(=O)OCC.Cn1c(=O)sc2cc(N)ccc21>>CCOC(=O)c1cn(-c2ccc3c(c2)sc(=O)n3C)c(=O)[nH]c1=O,,CCO,O,Cl,CC(C)(C)[O-].[K+],test
US04017627,CC(=O)c1ccc(O)c2ncccc12.[O-]Cl>>CC(=O)c1cc(Cl)c(O)c2ncccc12,,CO,O,CC(=O)O,,test
US20110196002A1,COC(=O)[C@@H](NC(=O)c1csc(-c2ccc(N)cc2)n1)C(C)C.O=C=Nc1ccc(F)cc1F>>COC(=O)[C@@H](NC(=O)c1csc(-c2ccc(NC(=O)Nc3ccc(F)cc3F)cc2)n1)C(C)C,,C1CCOC1,,,,test
US20160075711A1,CC(=O)S[K].CS(=O)(=O)OC1CCC(F)(CCC2c3ccccc3-c3cncn32)CC1>>CC(=O)SC1CCC(F)(CCC2c3ccccc3-c3cncn32)CC1,,CN(C)C=O,O,,,test
US20070219229A1,COC(=O)c1cnc(Cl)c2cc(C)n(C)c12.Cl>>Cc1cc2c(Cl)ncc(C(=O)O)c2n1C.Cl,,Cl,,,,test
US20070259851A1,CC(C)(C)OC(=O)N1CC=C(OS(=O)(=O)C(F)(F)F)CC1.COc1nc2ccn([Si](C(C)C)(C(C)C)C(C)C)c2cc1B(O)O>>COc1nc2ccn([Si](C(C)C)(C(C)C)C(C)C)c2cc1C1=CCN(C(=O)OC(C)(C)C)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US20160068515A1,CCN(CC)CCCl.O=c1[nH]ncn1-c1ccc(Br)cc1F>>CCN(CC)CCn1ncn(-c2ccc(Br)cc2F)c1=O,,CN(C)C=O,,Cl,[H-].[Na+],test
US20070208005A1,CC(C)(C)OC(=O)N1CCc2ccc(Cc3ccc(C(=O)O)cn3)cc2CC1.CN>>CNC(=O)c1ccc(Cc2ccc3c(c2)CCN(C(=O)OC(C)(C)C)CC3)nc1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20070299074A1,COC(=O)Cl.COc1cccc(OC)c1CNC(=N)Nc1nc(CN)cs1>>COC(=O)NCc1csc(NC(=N)NCc2c(OC)cccc2OC)n1,,C1CCOC1,,CN1CCOCC1,Cl,test
US20090197834A1,N#Cc1ccc(F)cc1.O=c1c(O)cn(C2CCCC2)c2cc(NC3CCCCC3)c(F)cc12>>N#Cc1ccc(Oc2cn(C3CCCC3)c3cc(NC4CCCCC4)c(F)cc3c2=O)cc1,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US05380722,COc1ccccc1N1CCNCC1.O=C(Nc1cccc2[nH]ccc12)c1ccccc1OCC1CO1>>COc1ccccc1N1CCN(CC(O)COc2ccccc2C(=O)Nc2cccc3[nH]ccc23)CC1,,CCO,,,,test
US20100216814A1,Cc1ccc(C=CBr)cn1.Cc1ccc2[nH]c3c(c2c1)CN(C)C(C)C3.O=C(O)[C@@H]1CCCN1>>C/C(=C\n1c2c(c3cc(C)ccc31)CN(C)C(C)C2)c1ccc(C)nc1,[Cu]I,CN(C)C=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20060173056A1,CC(C)(C)OC(=O)N1C[C@H](Nc2nc3ccccc3o2)C[C@H]1C(=O)O.Cl.N#C[C@@H]1CCCN1>>Cl.N#CC1CCCN1C(=O)[C@@H]1C[C@@H](Nc2nc3ccccc3o2)CN1,,CN(C)C=O,,,,test
US20060100262A1,COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CCN(CCN(C)C)Cc1ccccc1-3>>CN(C)CCN1CCn2c(c(C3CCCCC3)c3ccc(C(=O)O)cc32)-c2ccccc2C1,,CO,,[Na+].[OH-],,test
US20090233896A1,CC(C)(C)OC(=O)Nc1cc(CN2CCOCC2)ccn1>>Nc1cc(CN2CCOCC2)ccn1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20150191434A1,Ic1n[nH]c2cccnc12.O=C(Cl)c1c(Cl)cccc1C(F)(F)F>>O=C(c1c(Cl)cccc1C(F)(F)F)n1nc(I)c2ncccc21,,C1CCOC1,,[H-].[Na+],,test
US20080167287A1,CCN.O=C(O)C1(c2ccc(-c3cnc4ncc(C5(c6ccc7ncccc7c6)CC5)n4c3)cc2)CC1>>CCNC(=O)C1(c2ccc(-c3cnc4ncc(C5(c6ccc7ncccc7c6)CC5)n4c3)cc2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20120202785A1,C[C@@H](OCc1ccccc1)[C@H](NC(=O)OC(C)(C)C)c1nc2ccc(F)cc2n1-c1ccccc1>>C[C@@H](OCc1ccccc1)[C@H](N)c1nc2ccc(F)cc2n1-c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150210682A1,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCCCOC)cc1CC2C1(C)CC1>>COCCCOc1cc2c(cc1OC)-c1cc(=O)c(C(=O)O)cn1C(C1(C)CC1)C2,,CO,O,Cl,[Li]O,test
US03998808,C1=CCNCC1.O=C(Cl)CCl>>O=C(CCl)N1CC=CCC1,,c1ccccc1,,CCN(CC)CC,,test
US20160152623A1,CCOC(=O)c1[nH]ccc1NCc1ccc(C(F)(F)F)cc1C(OCC)OCC.O=C(N=C=S)c1ccccc1>>CCOC(OCC)c1cc(C(F)(F)F)ccc1Cn1c(=S)[nH]c(=O)c2[nH]ccc21,,CO,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050277662A1,COC(=O)c1cc(/C=C/N(C)C)c([N+](=O)[O-])cn1>>COC(=O)c1cc2cc[nH]c2cn1,,CO,,,,test
US03950526,Nc1ccc(Cl)cc1C(=O)C1CCCCC1.O=C(Cl)C(Cl)(Cl)Cl>>O=C(c1cc(Cl)ccc1NC(=O)C(Cl)(Cl)Cl)C1CCCCC1,,ClCCl,,CCN(CC)CC,CCOCC,test
US06956049B1,NC(=O)C=Cc1ccccc1.O=C(Cl)SCl>>O=c1oc(/C=C/c2ccccc2)ns1,,ClC(Cl)Cl,,,,test
US20050038068A1,CCOC(=O)c1c(-c2cc(C)cc(C)c2)csc1N.N#CCC(=O)O>>CCOC(=O)c1c(-c2cc(C)cc(C)c2)csc1NC(=O)CC#N,,CN(C)C=O,ClCCl,ClP(Cl)(Cl)(Cl)Cl,,test
US20140206819A1,COc1c(C(C)(C)C)cc2c(c1-c1ccccc1)CC(C)=C2.C[Si](C)(Cl)Cl>>COc1c(C(C)(C)C)cc2c(c1-c1ccccc1)C=C(C)C2[Si](C)(C)Cl,,Cc1ccccc1,,C1CCOC1,[Li]CCCC,test
US20020035102A1,CC(=O)O.CS(=O)(=O)C(=C1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1)c1cccc(C#N)c1>>CS(=O)(=O)C(=C1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1)c1cccc(C(N)=O)c1,,CCO,Cl,,,test
US20150225449A1,CC(=O)c1ccc(C(=O)O)cc1.C[C@@H]1Nc2ccccc2NC(=O)[C@H]1NC(=O)OC(C)(C)C>>CC(=O)c1ccc(C(=O)N2c3ccccc3NC(=O)[C@@H](NC(=O)OC(C)(C)C)[C@@H]2C)cc1,,O,c1ccncc1,O=P(Cl)(Cl)Cl,,test
US20060111375A1,CC[Mg]Br.COc1cc2nccc(Oc3cc(OCc4ccccc4)ccc3C=O)c2cc1OC>>CCC(O)c1ccc(OCc2ccccc2)cc1Oc1ccnc2cc(OC)c(OC)cc12,,C1CCOC1,,O,,test
US20040157886A1,Nc1ccc2c(c1)OCC(=O)N2.O=C(CCl)N1CCC(Oc2ccc(Cl)cc2)CC1>>O=C1COc2cc(NCC(=O)N3CCC(Oc4ccc(Cl)cc4)CC3)ccc2N1,,CO,,,,test
US20130059834A1,CC(C)(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3n[nH]c4ccc(OC(F)F)cc34)nc12.COC(=O)CCCBr>>COC(=O)CCCn1nc(-c2cnc3c(n2)c(C(=O)NC(C)(C)C)cn3COCC[Si](C)(C)C)c2cc(OC(F)F)ccc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090099231A1,CC(C)[Si](C(C)C)(C(C)C)n1cc(Cl)c2ccc(S(=O)(=O)N[C@H]3CCN(c4ccc5c(c4F)CCN(C(=O)OC(C)(C)C)C5)C3=O)cc21.Cl>>Cl.O=C1[C@@H](NS(=O)(=O)c2ccc3c(Cl)c[nH]c3c2)CCN1c1ccc2c(c1F)CCNC2,,C1COCCO1,CO,,,test
US05814378,O=S(=O)(OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F.Oc1ccc(-c2ccc(O)cc2)cc1>>Oc1ccc(-c2ccc(OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc2)cc1,,COCCOC,,Cl,[H-].[Na+],test
US20090029905A1,BrCc1ccccc1.CCOC(C)=O.COC(=O)c1cc(O)cc(O[C@@H](C)CO)c1>>COC(=O)c1cc(OCCc2ccccc2)cc(O[C@@H](C)CO)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05489592,CC=Cc1cc(Br)ccc1F.O=C1CCC(=O)N1Br>>Fc1ccc(Br)cc1C=CCBr,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20070281918A1,CCNc1c(OC)nc2c(c1Cl)C(C)CN(C(=O)C(F)(F)F)CC2>>CCNc1c(OC)nc2c(c1Cl)C(C)CNCC2,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20150321983A1,O=C(O)c1ccccc1.O=C(c1ccccc1)c1ccc(OCCO)cc1>>O=C(OCCOc1ccc(C(=O)c2ccccc2)cc1)c1ccccc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20120302755A1,CC1(C)OB(c2ccc(O)cc2)OC1(C)C.O=[N+]([O-])c1cc(Br)cnc1Br>>O=[N+]([O-])c1cc(Br)cnc1-c1ccc(O)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20140057899A1,C=C[C@@H](CCn1cc(I)c2c(Cl)ncnc21)NC(=O)OC(C)(C)C.N>>C=C[C@@H](CCn1cc(I)c2c(N)ncnc21)NC(=O)OC(C)(C)C,,COCCOC,,O,,test
US20150080549A1,O=C1OCN(C(=O)OCC2c3ccccc3-c3ccccc32)[C@H]1Cc1cscn1>>CN(C(=O)OCC1c2ccccc2-c2ccccc21)[C@@H](Cc1cscn1)C(=O)O,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US05538974,COC(=O)C1(CCCCBr)Sc2cc(OC)ccc2OCC1=O.c1ccc(N2CCNCC2)cc1>>COC(=O)C1(CCCCN2CCN(c3ccccc3)CC2)Sc2cc(OC)ccc2OCC1=O,,CC#N,,[I-].[K+],,test
US20160002255A1,COC(=O)/C=C(\OS(=O)(=O)C(F)(F)F)C1CCC1.OB(O)c1cccc(O)c1>>COC(=O)/C=C(\c1cccc(O)c1)C1CCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20080253988A1,CCOC(=O)c1cc2cnnc(Nc3cc(C(=O)O)ccc3OC)n2c1C.NC1CC1>>CCOC(=O)c1cc2cnnc(Nc3cc(C(=O)NC4CC4)ccc3OC)n2c1C,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20150031673A1,BrCCOCc1ccccc1.CCOC(=O)c1cc[nH]c1C>>CCOC(=O)c1ccn(CCOCc2ccccc2)c1C,,CN(C)C=O,,[H-].[Na+],,test
US20020019402A1,COC(=O)C1CC(=O)N(c2cccc(N)c2)C1.O=C=NCc1ccccc1>>COC(=O)C1CC(=O)N(c2cccc(NC(=O)NCc3ccccc3)c2)C1,,ClCCl,,,,test
US20110263562A1,BrCC1CCC1.C[C@@H](COC1CCN(c2nc3cc(O)ccc3o2)CC1)NC(=O)OC(C)(C)C>>C[C@@H](COC1CCN(c2nc3cc(OCC4CCC4)ccc3o2)CC1)NC(=O)OC(C)(C)C,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20080221148A1,COc1cc(C=O)ccc1O.Clc1ccc(CBr)cc1>>COc1cc(C=O)ccc1OCc1ccc(Cl)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150080438A1,COc1ccc2c(c1)CCCC(c1ccccc1)=C2C#CCCCO>>COc1ccc2c(c1)CCCC(c1ccccc1)=C2CCCCCO,[Pd],C1CCOC1,CCOC(C)=O,[H][H],,test
US20110160198A1,CC[C@@H](O)c1ccccc1.COC(=O)[C@H](Cc1ccc2c(c1)OC[C@H](c1ccc(OC(C)=O)cc1)O2)NS(=O)(=O)c1ccc([N+](=O)[O-])cc1>>CC[C@@H](c1ccccc1)N([C@@H](Cc1ccc2c(c1)OC[C@H](c1ccc(OC(C)=O)cc1)O2)C(=O)OC)S(=O)(=O)c1ccc([N+](=O)[O-])cc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05521147,Nc1cccc2c1OCC2=O.O=C1CCC(=O)N1Cl>>Nc1ccc(Cl)c2c1OCC2=O,,CN(C)C=O,,,,test
US05500361,CCCCCCCCCCCCCCN.O=C(CI)OC(=O)CI>>CCCCCCCCCCCCCCNC(=O)CI,,ClCCl,,,,test
US20090270405A1,CCOC(OCC)C(=N)OC.Cc1ccc(CN)cc1>>Cc1ccc2cnc(N)cc2c1,,CO,,,,test
US20040053931A1,Cc1noc(C)c1B(O)O.O=S(=O)(Oc1ccnc2[nH]ccc12)C(F)(F)F>>Cc1noc(C)c1-c1ccnc2[nH]ccc12,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20110076292A1,CC(C)(O)Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.CC(C)n1ccnc1-c1cn2c(n1)-c1ccc(Br)cc1OCC2>>CC(C)n1ccnc1-c1cn2c(n1)-c1ccc(-c3cnn(CC(C)(C)O)c3)cc1OCC2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20130102621A1,CS(=O)(=O)c1ccc(Nc2ncnc3c(C4CCNCC4)coc23)c(F)c1.O=C(Cl)OCc1ccccc1>>CS(=O)(=O)c1ccc(Nc2ncnc3c(C4CCN(C(=O)OCc5ccccc5)CC4)coc23)c(F)c1,,ClCCl,c1ccncc1,Cl,O,test
US05089633,CCCOc1oc(=O)c2cc(N)ccc2c1Cl.CCN=C=O>>CCCOc1oc(=O)c2cc(NC(=O)NCC)ccc2c1Cl,,C1CCOC1,,,,test
US04638070,BrBr.CCC(=O)c1ccc2c(c1)OCC2>>CC(Br)C(=O)c1ccc2c(c1)OCC2,,C1CCOC1,,,,test
US20130296329A1,COCc1cc(F)c([N+](=O)[O-])cc1C(=O)OC.c1c[nH]c(C2CCOC2)n1>>COCc1cc(-n2ccnc2C2CCOC2)c([N+](=O)[O-])cc1C(=O)OC,,CCN(CC)CC,,CC#N,,test
US20100087427A1,CC(C)(C)OC(=O)N1C[C@H](C=O)[C@@H](Cc2ccccc2)C1.Clc1ccc(NC2CCCCC2)cc1>>CC(C)(C)OC(=O)N1C[C@H](CN(c2ccc(Cl)cc2)C2CCCCC2)[C@@H](Cc2ccccc2)C1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130331377A1,CCCc1cc(=O)[nH]c(Nc2ccc3cc[nH]c3c2)n1.O=P(Cl)(Cl)Cl>>CCCc1cc(Cl)nc(Nc2ccc3cc[nH]c3c2)n1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20070244118A1,CCOC(CCN(C(N)=O)C1CCNCC1)OCC.O=C(O)[C@H](O)CS(=O)(=O)c1ccc2cc(Cl)ccc2c1>>O=C([C@H](O)CS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCC(N2CCC(O)NC2=O)CC1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20090054427A1,C=CCOC(=O)C1(Cc2cc(F)c([N+](=O)[O-])c(F)c2)CSCC(NC(=O)OC(C)(C)C)C1=O>>CC(C)(C)OC(=O)N[C@H]1CSC[C@@H](Cc2cc(F)c([N+](=O)[O-])c(F)c2)C1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,,,test
US03962249,CC1CN(CCCc2ccccc2)CCN1.Cc1ccoc1C(=O)Cl>>Cc1ccoc1C(=O)N1CCN(CCCc2ccccc2)CC1C.Cl,,c1ccccc1,,,,test
US20070213331A1,CC(=O)N1[C@@H](Cc2cc(F)cc(F)c2)[C@@H]([C@H]2C[C@@H](OCCC(C)(C)O)CN2C(=O)OC(C)(C)C)OC1(C)C.Cl>>CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)[C@H]1C[C@@H](OCCC(C)(C)O)CN1.Cl,,C1COCCO1,,,,test
US20150175594A1,C1COC2(CCC3(CC2)COC3)O1>>O=C1CCC2(CC1)COC2,,CC(=O)O,,,,test
US20050234265A1,CC(C)(C)c1ccc(C=O)c(O)c1.CCCN>>CCCNCc1ccc(C(C)(C)C)cc1O,,CO,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20040209905A1,CCCCN.COc1cc2ncnc(Oc3ccc(N)c(F)c3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCCCNC(=O)Nc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1F,,CCN(CC)CC,ClC(Cl)Cl,CO,,test
US20030013715A1,C[C@H](CN)c1ccccc1.O=C(Cl)c1cnc2ccccc2n1>>C[C@H](CNC(=O)c1cnc2ccccc2n1)c1ccccc1,,O,,c1ccncc1,,test
US20030134889A1,C1=CCC=C1.CC(C)(C)OC(=O)N1C(=O)C=CC1C(C)(C)O[SiH2]C(C)(C)C>>CC(C)(C)OC(=O)N1C(=O)C2C3C=CC(C3)C2C1C(C)(C)O[SiH2]C(C)(C)C,,Cc1ccccc1,,,,test
US20020156081A1,CN1CCN([C@H]2CC[C@@H](n3nc(I)c4c(N)ncnc43)CC2)CC1.COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1NC(=O)OCc1ccccc1>>COc1cc(-c2nn([C@@H]3CC[C@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)OCc1ccccc1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20050004164A1,CC(C)(C)OC(=O)CC#N.O=Cc1ccnc2ccccc12>>CC(C)(C)OC(=O)C(C#N)=Cc1ccnc2ccccc12,,CCO,,,,test
US06184225B2,COCCO.COc1cc2c(Nc3cc(OC(C)=O)c(Cl)cc3F)ncnc2cc1O>>COCCOc1cc2ncnc(Nc3cc(OC(C)=O)c(Cl)cc3F)c2cc1OC,,ClCCl,,CCCCP(CCCC)CCCC,,test
US05430032,O=C1c2ccc(Cl)cc2SCc2cccnc21>>OC1c2ccc(Cl)cc2SCc2cccnc21,,CO,,O,[BH4-].[Na+],test
US20040110749A1,CC1(C)CC(SCc2c(C(F)(F)F)nn(-c3ccccc3)c2Cl)=NO1.O=C(OO)c1cccc(Cl)c1>>CC1(C)CC(S(=O)(=O)Cc2c(C(F)(F)F)nn(-c3ccccc3)c2Cl)=NO1,,ClC(Cl)Cl,,O,,test
US20060166992A1,COc1cc(N)cc(OC)c1OC.Cc1ncc(-c2nc(-n3cncn3)c3c(C)nc(C)n3n2)s1>>COc1cc(Nc2nc(-c3cnc(C)s3)nn3c(C)nc(C)c23)cc(OC)c1OC,,CN(C)C=O,,CO,O=C([O-])[O-].[K+].[K+],test
US20090069296A1,CCOC(=O)Cl.NCC1Cc2cc3c(cc21)OCO3>>CCOC(=O)NCC1Cc2cc3c(cc21)OCO3,,ClCCl,,O,[Na+].[OH-],test
US20140142082A1,Cc1ccc(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)n1S(=O)(=O)N1CCCCC1.N.O=S(=O)(O)Cl>>Cc1c(S(N)(=O)=O)cc(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)n1S(=O)(=O)N1CCCCC1,,ClCCl,,,,test
US20140349995A1,COC1CCN(c2nc(Cl)nc3c2CN([C@@H](C)c2ccccc2)CC3)CC1(C)C.Cc1cccc(C)c1B(O)O>>COC1CCN(c2nc(-c3c(C)cccc3C)nc3c2CN([C@@H](C)c2ccccc2)CC3)CC1(C)C,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20150225449A1,C[C@@H](C(=O)N[C@@H]1C(=O)Nc2ccccc2N(C(=O)C2CCOCC2)[C@H]1C)N(C)C(=O)OC(C)(C)C.N#Cc1ccccc1-n1nc(CBr)c2ccccc21>>C[C@@H](C(=O)N[C@@H]1C(=O)N(Cc2nn(-c3ccccc3C#N)c3ccccc23)c2ccccc2N(C(=O)C2CCOCC2)[C@H]1C)N(C)C(=O)OC(C)(C)C,,CCOC(C)=O,CN(C)C=O,[I-].[Na+],O=C([O-])[O-].[Cs+].[Cs+],test
US20080287517A1,Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(O)cc1.O=S(=O)(Cl)CCCF>>Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(OS(=O)(=O)CCCF)cc1,,ClCCl,,O,,test
US20030125370A1,CN(C(=O)[C@@H]1CCCN1)C1CC1>>CN(C[C@@H]1CCCN1)C1CC1,,C1CCOC1,,B,Cl,test
US20120264749A1,CCOC(=O)c1ccc(OCC(C)(C)O)c(C)c1>>Cc1cc(C(=O)O)ccc1OCC(C)(C)O,,CCO,O,[Na+].[OH-],,test
US20120088748A1,CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(Cl)c(F)c2)[C@H](C=O)C1.Nc1ccccn1>>CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(Cl)c(F)c2)[C@H](CNc2ccccn2)C1,,C1CCOC1,CO,,,test
US20090118263A1,C1COCCN1.CCCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(CN(CCCCl)Cc4cccc(CC(=O)OC)c4)cc3)c2n1>>CCCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(CN(CCCN4CCOCC4)Cc4cccc(CC(=O)OC)c4)cc3)c2n1,,CN(C)C=O,,[I-].[K+],,test
US06069156,CCCc1[nH]c2cc(C(N)=O)ccc2c1C(=O)C(C)C.Clc1ccc(CBr)cc1>>CCCc1c(C(=O)C(C)C)c2ccc(C(N)=O)cc2n1Cc1ccc(Cl)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090209552A1,CCOP(=O)(CC#N)OCC.O=Cc1cc([N+](=O)[O-])cc(C(F)(F)F)c1>>N#CC=Cc1cc([N+](=O)[O-])cc(C(F)(F)F)c1,,C1CCOC1,,O,[H-].[Na+],test
US04596823,NN.S=C=NCc1ccccc1>>NNC(=S)NCc1ccccc1,,C1COCCO1,,,,test
US20140194415A1,CC(Br)c1ccc(Br)cc1.O=C1COC2(CCNCC2)CN1C1CC1>>CC(c1ccc(Br)cc1)N1CCC2(CC1)CN(C1CC1)C(=O)CO2,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20160016963A1,CB1OB(C)OB(C)O1.O=C1NCCCn2c1cc1cc(F)cc(Br)c12>>Cc1cc(F)cc2cc3n(c12)CCCNC3=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150210682A1,CCOC=C(C(C)=O)C(=O)OCC.COCCCOc1cc2c(c(Cl)c1F)C=NC(C(C)C)C2>>CCOC(=O)C1=CN2C(CC1=O)c1c(cc(OCCCOC)c(F)c1Cl)CC2C(C)C,,CCO,,,,test
US20050075339A1,CCOC(=O)N=NC(=O)OCC.ClCCl.O=c1[nH]c(=O)n(-c2ccccc2)nc1Cc1c(F)cccc1F.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>N[C@@H](Cn1c(=O)c(Cc2c(F)cccc2F)nn(-c2ccccc2)c1=O)c1ccccc1,,C1CCOC1,ClCCl,O=C(O)C(F)(F)F,,test
US20060100230A1,CCOC(=O)COc1ccc(S(=O)(=O)N2c3c(C)cc(Br)cc3C(C)C2C)cc1C.OB(O)c1ccc(C(F)(F)F)cc1>>Cc1cc(S(=O)(=O)N2c3c(C)cc(-c4ccc(C(F)(F)F)cc4)cc3C(C)C2C)ccc1OCC(=O)O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20110224193A1,CP(C)(=O)Cl.O=C(Nc1ccc(N2CCC(O)CC2)nc1)c1oc(-c2ccccc2)nc1C(F)(F)F>>CP(C)(=O)OC1CCN(c2ccc(NC(=O)c3oc(-c4ccccc4)nc3C(F)(F)F)cn2)CC1,,ClCCl,O,CCN(CC)CC,CN(C)C=O,test
US04406909,BrBr.CC(=O)C(C)(C)CSc1ccc(Cl)cc1>>CC(C)(CSc1ccc(Cl)cc1)C(=O)CBr,,ClC(Cl)(Cl)Cl,,,,test
US20050165001A1,CC(C)(C)OC(=O)N1CCN(c2c(F)ccc(F)c2C#N)CC1.NCc1ccccc1>>CC(C)(C)OC(=O)N1CCN(c2c(F)ccc(NCc3ccccc3)c2C#N)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06555563B1,CSc1ccc(N2CC(O)(C(F)(F)F)N=C2c2nnc(C(C)C)s2)cc1>>CSc1ccc(-n2cc(C(F)(F)F)nc2-c2nnc(C(C)C)s2)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05952266,O=C(O)c1cc(Cl)c2c(c1Cl)C1(CCS2(=O)=O)OCCO1.O=C1CCCC(=O)C1>>O=C1C=C(OC(=O)c2cc(Cl)c3c(c2Cl)C2(CCS3(=O)=O)OCCO2)CCC1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US05536821,CCCCCC(N)N.CCOC(=O)C(F)(F)F>>NCCCCCCNC(=O)C(F)(F)F,,CO,,CCN(CC)CC,,test
US20040002524A1,COc1ccc(-n2c(-c3ccccc3C)nc3ccccc32)c(C)c1>>Cc1ccccc1-c1nc2ccccc2n1-c1ccc(O)cc1C,,ClCCl,,BrB(Br)Br,,test
US20100204236A1,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21.ClCCl.O=C([O-])c1ncccc1-c1ccc(CCCO)cc1.c1ccncc1>>O=CCCc1ccc(-c2cccnc2C(=O)OCc2ccccc2)cc1,,ClCCl,,,,test
US20140005213A1,COCCOc1ccc2ccc(C)nc2c1C.O=[Se]=O>>COCCOc1ccc2ccc(C=O)nc2c1C,,C1COCCO1,O,,,test
US20120295884A1,CNC.CS(=O)(=O)OCCOc1ccc2c(c1)c(CC(=O)N1[C@@H]3C[C@@H]3C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O>>CN(C)CCOc1ccc2c(c1)c(CC(=O)N1[C@@H]3C[C@@H]3C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O,,CCO,,,,test
US20080033007A1,CN1CCc2cc(OCc3ccccc3)c(OCc3ccccc3)cc2C1Cc1ccc(-c2ccccc2)cc1.Cl>>CN1CCc2cc(O)c(O)cc2C1Cc1ccc(-c2ccccc2)cc1.Cl,,CO,Cl,,,test
US20010039344A1,CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)O)cc1C(F)(F)F.Nc1ccccn1>>CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)Nc2ccccn2)cc1C(F)(F)F,c1ccncc1,ClCCl,,O=C1CCC(=O)N1Br,,test
US20150141423A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)CCSc1cnc(N)s1>>COC(=O)CCSc1cnc(NC(=O)OC(C)(C)C)s1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20080021059A1,CCN.CCOC(=O)c1cc(-c2cccnc2)cc2nc(N)nn12>>CCNC(=O)c1cc(-c2cccnc2)cc2nc(N)nn12,,C1CCOC1,,,,test
US20070167506A1,COC(=O)c1cccc(C(=O)O)c1.c1ccc(Cn2ccnc2)cc1>>COC(=O)c1cccc(C(=O)c2nccn2Cc2ccccc2)c1,,CC#N,,CCN(CC)CC,O=S(Cl)Cl,test
US06107297,Clc1ccc(Cl)nn1.O=c1[nH]cc(C2c3ccccc3C=Cc3ccccc32)c(=O)[nH]1>>O=c1[nH]c(=O)n(-c2ccc(Cl)nn2)cc1C1c2ccccc2C=Cc2ccccc21,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160272637A1,COc1cn(C(Cc2cnco2)C(=O)OC(C)(C)C)c(=O)cc1-c1cc(Cl)ccc1C#N>>COc1cn(C(Cc2cnco2)C(=O)O)c(=O)cc1-c1cc(Cl)ccc1C#N,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120082646A1,COc1c(I)cc(N)cc1C(C)(C)C.O=C(Cl)OCCCl>>COc1c(I)cc(NC(=O)OCCCl)cc1C(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US04628057,COC(=O)[C@H]1Cc2c([nH]c3ccccc23)[C@H](CO)N1>>O=C(O)[C@H]1Cc2c([nH]c3ccccc23)[C@H](CO)N1,,CO,,[Na+].[OH-],,test
US20080269219A1,Cc1ccccc1OCCCc1oc(-n2ccnc2C)nc1-c1ccc(Cl)cc1.Cl>>Cc1ccccc1OCCCc1oc(-n2ccnc2C)nc1-c1ccc(Cl)cc1.Cl,,CC(C)=O,,,,test
US20090082356A1,C1COCCN1.NS(=O)(=O)c1cccc(C(=O)O)c1>>NS(=O)(=O)c1cccc(C(=O)N2CCOCC2)c1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US05382592,C#CCCO[Si](C)(C)C(C)(C)C.C[Si](C)(C)Cl>>CC(C)(C)[Si](C)(C)OCCC#C[Si](C)(C)C,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20070135477A1,COc1cc([N+](=O)[O-])c(N)cc1OCN1CCC(C)CC1>>COc1cc(N)c(N)cc1OCN1CCC(C)CC1,[Pd],CO,,,,test
US20040259950A1,CC(=O)Oc1cc(-c2ccccc2)c(O)c(-c2ccccc2)c1.CCOC(=O)CBr>>CCOC(=O)COc1c(-c2ccccc2)cc(OC(C)=O)cc1-c1ccccc1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160115125A1,CCOC(=O)c1c(F)c(S(=O)(=O)Cl)cn1C.C[C@@H](N)C(C)(F)F>>CCOC(=O)c1c(F)c(S(=O)(=O)N[C@H](C)C(C)(F)F)cn1C,,CC#N,,Cl,O=C([O-])O.[Na+],test
US20100298387A1,O=C(O)c1ccccc1F.O=S(=O)(O)Cl>>O=C(O)c1cc(S(=O)(=O)Cl)ccc1F,,[Na+],[OH-],,,test
US03932430,O=C1c2ccccc2CC1Br.O=Cc1ccc(Cl)cc1>>O=C1c2ccccc2CC12OC2c1ccc(Cl)cc1,,CO,,C[O-].[Na+],,test
US20070051919A1,Fc1ccc(C=Cc2ccc(-c3ccc4ccccc4c3)cc2F)cc1>>Fc1ccc(CCc2ccc(-c3ccc4ccccc4c3)cc2F)cc1,[Pd],Cc1ccccc1,,,,test
US06197727B1,C#CCBr.Cc1c(C(F)(F)F)cnn(-c2cc(O)c(Cl)cc2F)c1=O>>C#CCOc1cc(-n2ncc(C(F)(F)F)c(C)c2=O)c(F)cc1Cl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160207883A1,COC(=O)C(C)(C)CN1CCN(c2ccc(Nc3cc(OC)ncc3NC(C)=O)cc2)CC1>>COc1cc(Nc2ccc(N3CCN(CC(C)(C)C(=O)O)CC3)cc2)c(NC(C)=O)cn1,,CO,,Cl,[Na+].[OH-],test
US20040110960A1,ClP(Cl)Cl.Oc1ccccc1>>ClP(Cl)Oc1ccccc1,,CCN(CC)CC,,,,test
US20150183804A1,O=C(CBr)c1ccncc1.O=c1cc(N2CC3CCC(C2)O3)nc2n1CC[C@@H](C(F)(F)F)N2>>O=C(CN1c2nc(N3CC4CCC(C3)O4)cc(=O)n2CC[C@H]1C(F)(F)F)c1ccncc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05648354,CC(C)(C)[Si](C)(C)OCC1=CC=C(COc2ccccc2C(F)(F)F)SS1>>OCC1=CC=C(COc2ccccc2C(F)(F)F)SS1,,C1CCOC1,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110281854A1,O=C(Cl)OCC(Cl)(Cl)Cl.OC[C@@H]1CN[C@H](c2ccccc2)CO1>>O=C(OCC(Cl)(Cl)Cl)N1C[C@@H](CO)OC[C@H]1c1ccccc1,,C1CCOC1,,[Na+].[OH-],,test
US05013737,NC(=O)c1cnn2c1NCC=C2c1ccccc1.S=C(n1ccnc1)n1ccnc1>>O=c1[nH]c(=S)n2c3c1cnn3C(c1ccccc1)=CC2,,C1CCOC1,,[H-].[Na+],,test
US20150166558A1,BrCc1ccccc1.CCOC(=O)CCC1CCNCC1>>CCOC(=O)CCC1CCN(Cc2ccccc2)CC1,,O,,CC#N,CCN(CC)CC,test
US06960607B2,CNN.COc1ccc(C(=O)c2ccc3cc(OC)ccc3c2)c(F)c1>>COc1ccc2cc(-c3nn(C)c4cc(OC)ccc34)ccc2c1,CN(C)c1ccncc1,O,,c1ccncc1,,test
US20100190981A1,CCOC(C)n1cc(-c2ncnc3c2ccn3COCC[Si](C)(C)C)cn1>>C[Si](C)(C)CCOCn1ccc2c(-c3cn[nH]c3)ncnc21,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20110142796A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2csc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)n2)CC1>>O=C(c1csc(Nc2ncc3c4ccncc4n(C4CCCC4)c3n2)n1)N1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06451839B1,CCc1c(NC(N)=O)c2c(OCC(=O)OC(C)(C)C)cccc2n1Cc1ccccc1Br>>CCc1c(NC(N)=O)c2c(OCC(=O)O)cccc2n1Cc1ccccc1Br,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030092576A1,CC1=C(C2=NOC(CCl)C2)C(C)C(=S(=O)=O)C=C1C(=O)C1=C(O)C(C)CC(C)C1=O>>CC1=C(C2=NOC3CC23)C(C)C(=S(=O)=O)C=C1C(=O)C1=C(O)C(C)CC(C)C1=O,,CS(C)=O,,Cl,CC(C)(C)[O-].[K+],test
US20060241115A1,COc1cc2nccc(Oc3ccc4cc(NC(=O)OCc5ccccc5)ccc4c3)c2cc1OC>>COc1cc2nccc(Oc3ccc4cc(N)ccc4c3)c2cc1OC,[Pd],CCOC(C)=O,,,,test
US20140364435A1,C[C@H](N)CO.Clc1ccc2ncc(Br)n2n1>>C[C@H](N)COc1ccc2ncc(Br)n2n1,,C1CCOC1,CN(C)C=O,O,[H-].[Na+],test
US20060040961A1,NCC1SCCS1.Oc1ccc(-c2oc3ncnc(Cl)c3c2-c2ccccc2)cc1>>Oc1ccc(-c2oc3ncnc(NCC4SCCS4)c3c2-c2ccccc2)cc1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20040110767A1,C1CCNC1.O=CCCc1ccc(N(Cc2ccc(O)cc2)S(=O)(=O)c2ccccc2)cc1>>O=S(=O)(c1ccccc1)N(Cc1ccc(O)cc1)c1ccc(CCCN2CCCC2)cc1,,ClCCl,,O=C([O-])O.[Na+],,test
US20110306621A1,COC(=O)c1ccc2cccc(-c3ccnn3C)c2c1.O=C1CCC(=O)N1Cl>>COC(=O)c1ccc2cccc(-c3c(Cl)cnn3C)c2c1,,O,,CC(=O)O,,test
US20120322785A1,Cc1ccncc1-c1cc2cnc(NC(=O)OC(C)(C)C)cc2cn1>>Cc1ccncc1-c1cc2cnc(N)cc2cn1,,ClCCCl,,O=C(O)C(F)(F)F,,test
US20110009405A1,COc1ncc([N+](=O)[O-])cn1>>COc1ncc(N)cn1,[Pd],CO,,,,test
US20070197520A1,CC[Mg]Br.Nc1cccc(Cl)c1C=O>>CCC(O)c1c(N)cccc1Cl,,CCOC(C)=O,,,,test
US20090156600A1,CCOC(=O)C(Cc1ccc(S(C)(=O)=O)cc1)C(=O)C(C)C.COC(=O)COc1ccc(Cl)c(N)c1>>COC(=O)COc1ccc(Cl)c2[nH]c(C(C)C)c(Cc3ccc(S(C)(=O)=O)cc3)c(=O)c12,,O,,C1COCCO1,,test
US20150252022A1,Cc1cc2cc(-c3cnn(C4CCCCO4)c3)ccc2n1CC1CC(C)N(C(=O)CCc2ccccc2)C1>>Cc1cc2cc(-c3cn[nH]c3)ccc2n1CC1CC(C)N(C(=O)CCc2ccccc2)C1,,CO,ClCCl,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20140094465A1,COC(=O)c1ccc(COc2ccc(OC(C)=O)cc2F)c(F)c1>>O=C(O)c1ccc(COc2ccc(O)cc2F)c(F)c1,,CO,,Cl,[Na+].[OH-],test
US20070213355A1,CN(C)CCc1ccc(N)cc1.CN1CCCC1=O.O=[N+]([O-])c1cnc2ccc(Br)cc2c1Cl>>CN(C)CCc1ccc(-n2c(N(C)C)nc3cnc4ccc(Br)cc4c32)cc1,,CN1CCCC1=O,,CCOC(C)=O,,test
US20150246063A1,CCOP(=O)(CCCNC(=O)c1ccc2c(C(F)(F)F)c(OCc3cc(Cl)cc(Cl)c3)ccc2c1)OCC>>O=C(NCCCP(=O)(O)O)c1ccc2c(C(F)(F)F)c(OCc3cc(Cl)cc(Cl)c3)ccc2c1,,CC#N,CCOC(C)=O,C[Si](C)(C)Br,,test
US05700454,NCCO.O=C(O)CCC(=O)NCCS>>O=C(CCC(=O)NCCS)NCCO,,CO,,,,test
US20130040945A1,C1CCNC1.COc1ccc(C[C@H]2COC(=O)[C@@H]2Cc2ccc(OC(=O)Cl)c(OC)c2)cc1OC>>COc1ccc(C[C@H]2COC(=O)[C@@H]2Cc2ccc(OC(=O)N3CCCC3)c(OC)c2)cc1OC,,ClCCl,,[Cl-].[NH4+],,test
US20100298336A1,COC(=O)c1cc(Cl)sc1Cl>>OCc1cc(Cl)sc1Cl,,CO,,[BH4-].[Na+],[Cl-].[NH4+],test
US20080119511A1,COC(=O)C[C@@H](c1ccc(OCc2cc(C)c3c(c2)CCCC3)cc1)c1nncn1C>>Cc1cc(COc2ccc([C@H](CC(=O)O)c3nncn3C)cc2)cc2c1CCCC2,,C1CCOC1,CCO,[Li+].[OH-],,test
US20090012075A1,CC(C)(C)OC(=O)Nc1ccc(-c2cccs2)cc1NC(=O)c1cc2ccc(C(F)C(N)=O)cc2s1>>NC(=O)C(F)c1ccc2cc(C(=O)Nc3cc(-c4cccs4)ccc3N)sc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040209857A1,C=CCN([C@H](C(=O)N1CC[C@H](O)C1)c1ccccc1)S(=O)(=O)c1ccccc1[N+](=O)[O-].CC(C)(C)[Si](C)(C)Cl>>C=CCN([C@H](C(=O)N1CC[C@H](O[Si](C)(C)C(C)(C)C)C1)c1ccccc1)S(=O)(=O)c1ccccc1[N+](=O)[O-],,CN(C)C=O,,O,c1c[nH]cn1,test
US20060194816A1,CCOC(=O)c1c(C(=O)c2ccc(Cl)cc2Cl)oc2cc(O)ccc12.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1c(C(=O)c2ccc(Cl)cc2Cl)oc2cc(OS(=O)(=O)C(F)(F)F)ccc12,,ClCCl,,CCN(CC)CC,,test
US20130210831A1,CCS(=O)(=O)Cl.CN(c1ccc(N)cn1)[C@@H]1CCN(c2ncnc3c2ccn3COCC[Si](C)(C)C)C1>>CCS(=O)(=O)Nc1ccc(N(C)[C@@H]2CCN(c3ncnc4c3ccn4COCC[Si](C)(C)C)C2)nc1,,ClCCl,,CCN(CC)CC,,test
US20080161592A1,CCOP(=O)(OCC)C(F)(F)c1ccc(C)cc1[N+](=O)[O-]>>CCOP(=O)(OCC)C(F)(F)c1ccc(C)cc1N,[Pd],CCO,CCOC(C)=O,,,test
US20040038998A1,COc1ccc2nccc(N)c2c1.O=C(n1ccnc1)n1ccnc1>>COc1ccc2nccc(NC(=O)n3ccnc3)c2c1,,CCO,,,,test
US20130245021A1,Clc1ccc2ncc(Br)n2n1.NCCCc1ccccc1>>Brc1cnc2ccc(NCCCc3ccccc3)nn12,,CCCO,,,,test
US20150225449A1,COc1ccc2ccccc2c1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)[C@H](C)N(C(=O)C2CCOCC2)c2cc(C#N)ccc21.Cl>>CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccc(C#N)cc2N(C(=O)C2CCOCC2)[C@H]1C.Cl,,C1COCCO1,CCOCC,,,test
US20080039456A1,NNC(=O)c1cc2oc(-c3ccc([N+](=O)[O-])cc3)cc2[nH]1.S=C(Cl)Cl>>O=c1[nH][nH]c(=S)n2c1cc1oc(-c3ccc([N+](=O)[O-])cc3)cc12,,C1CCOC1,O,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US20110218201A1,COc1cccc2c1OC(C)(C)C2.O=C1CCC(=O)N1Br>>COc1cc(Br)cc2c1OC(C)(C)C2,,CC1CCCO1,,CCOCC,O,test
US20140163026A1,CNC(=O)c1cc(-c2ccc(CC(=O)OC)c(Cl)c2)ccn1.CNc1nc(Cl)ncc1C=O>>CNC(=O)c1cc(-c2ccc(-c3cc4cnc(Cl)nc4n(C)c3=O)c(Cl)c2)ccn1,,CS(C)=O,,C1CCC2=NCCCN2CC1,O,test
US06291399B1,COC(=O)Cl.CON=C1COc2cc(OCc3ccccc3NO)ccc21>>CON=C1COc2cc(OCc3ccccc3N(O)C(=O)OC)ccc21,,ClCCl,,c1ccncc1,,test
US20040102432A1,NCCN1CCC(Oc2ccc(F)c(F)c2)CC1.O=CC1CC1>>Fc1ccc(OC2CCN(CCNCC3CC3)CC2)cc1F,,CO,,,,test
US20030225142A1,OCCCCCC=C1CCCCC1>>OCCCCCCC1CCCCC1,[Pd],,,,,test
US20080287517A1,Cc1c(C(=O)OCC(Cl)(Cl)Cl)nn(-c2ccccc2Cl)c1-c1ccc(OCc2ccccc2)cc1>>Cc1c(C(=O)OCC(Cl)(Cl)Cl)nn(-c2ccccc2Cl)c1-c1ccc(O)cc1,,Br,CC(=O)O,CCO,,test
US20060106048A1,CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(/C=C/C(=O)OC)c(C)c1)=NC(C)(C)C2>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(/C=C/C(=O)O)c(C)c1)=NC(C)(C)C2,,CO,,Cl,[Na+].[OH-],test
US20120220565A1,CCO.O=C(Cl)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(N3CCOCC3)nc1)C2>>CCOC(=O)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(N3CCOCC3)nc1)C2,,ClCCl,,CCN(CC)CC,,test
US20120028986A1,Clc1ccc(Cl)nn1.OCCc1ccccc1>>Clc1ccc(OCCc2ccccc2)nn1,,CN1CCCC1=O,,[H-].[Na+],,test
US20120214762A1,C1=COCCC1.CC(=O)c1cc(CO)on1>>CC(=O)c1cc(COC2CCCCO2)on1,,ClCCl,O,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US06239131B1,CC(C)(C)OC(=O)CBr.O=C(NC1CN(c2ccccc2)c2ccccc2NC1=O)OCc1ccccc1>>CC(C)(C)OC(=O)CN1C(=O)C(NC(=O)OCc2ccccc2)CN(c2ccccc2)c2ccccc21,,C1CCOC1,,O,[H-].[Na+],test
US20100331293A1,Cc1c(N2CCN(C)CC2=O)nc2cc(F)cc(F)c2c1Cl.Nc1cc(N2CCOCC2)cnc1N1CCOCC1>>Cc1c(N2CCN(C)CC2=O)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)cnc1N1CCOCC1,,Cc1ccccc1,,,,test
US20090247526A1,CCO.Cc1ncc(C(=O)O)c(C)c1Oc1ccnc(Cl)c1>>CCOC(=O)c1cnc(C)c(Oc2ccnc(Cl)c2)c1C,,c1ccccc1,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US20090042917A1,CCC(C)c1c(Cl)nc(SC)nc1N(CC(F)(F)F)C(=O)OC(C)(C)C>>CCC(C)c1c(Cl)nc(SC)nc1NCC(F)(F)F,,O,,ClCCl,O=C(O)C(F)(F)F,test
US20020013328A1,C=O.CC(C)c1[nH]n(-c2c(Cl)cc(Cl)cc2Cl)c2nc(Cc3cccc(O)c3)nc(=O)c1-2.CNC>>CC(C)c1[nH]n(-c2c(Cl)cc(Cl)cc2Cl)c2nc(Cc3ccc(CN(C)C)c(O)c3)nc(=O)c1-2,,CC(=O)O,,O,,test
US20010020089A1,Clc1nc(Cl)c2ncn(C3CCCCO3)c2n1.NCC(c1ccccc1)c1ccccc1>>Clc1nc(NCC(c2ccccc2)c2ccccc2)c2ncn(C3CCCCO3)c2n1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20060257987A1,CC(CCOc1ccc(C(F)(F)F)cc1Oc1ccccc1)OS(C)(=O)=O.COC(=O)CCc1ccc(S)cc1C>>Cc1cc(S[C@H](C)CCOc2ccc(C(F)(F)F)cc2Oc2ccccc2)ccc1CCC(=O)O,,CN(C)C=O,CO,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20120022064A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc3c(c2)CCC(=O)N3c2ccc(F)cc2)CC1.Cl>>Cl.O=C1CCc2cc(OC3CCNCC3)ccc2N1c1ccc(F)cc1,,CCO,CCOC(C)=O,,,test
US05665718,N#Cc1ncn2c1[C@@H]1CCN1C(=O)c1c-2cccc1C(F)(F)F.NO>>NC(=NO)c1ncn2c1[C@@H]1CCN1C(=O)c1c-2cccc1C(F)(F)F,,CO,,Cl,[Na],test
US20070082053A1,CC1CN(CC(Cc2ccccc2)C(=O)O)CCC1(C)c1cccc(O)c1>>C[C@H]1CNCC[C@@]1(C)c1cccc(O)c1,,O,,CO,,test
US20050054670A1,CC(C)(C)c1ccc(N2C(=O)c3c([N+](=O)[O-])cccc3C2(C)O)cc1>>CC(C)(C)c1ccc(N2C(=O)c3c(N)cccc3C2(C)O)cc1,,CO,,[BH4-].[Na+],,test
US20100215579A1,FCCOCCOCCCl.O=[N+]([O-])c1ccc(-c2ccc3cc(O)ccc3c2)cc1>>O=[N+]([O-])c1ccc(-c2ccc3cc(OCCOCCOCCF)ccc3c2)cc1,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20160168139A1,COC(=O)c1ccc([N+](=O)[O-])cc1Oc1ccccc1Br>>O=C(O)c1ccc([N+](=O)[O-])cc1Oc1ccccc1Br,,ClCCl,,CO,[Na+].[OH-],test
US20130225524A1,CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(-c4ccnc(OC)c4OC)ccc23)c1>>NC(=O)c1cnc2cc(-c3ccnc(O)c3O)ccc2c1Nc1cccc(C(=O)O)c1,,ClCCl,,BrB(Br)Br,,test
US06159904,CCOC(=O)c1ccc2c(c1C)C(OS(C)(=O)=O)C(C)(C)CS2(=O)=O.CCS>>CCSC1c2c(ccc(C(=O)O)c2C)S(=O)(=O)CC1(C)C,,CCOC(C)=O,CO,C[O-].[Na+],,test
US20100004287A1,COC(=O)CC(=O)NNC(=O)c1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)cc1.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>COC(=O)Cc1nnc(-c2ccc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)cc2)s1,,C1CCOC1,,,,test
US20130150343A1,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCC(O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]5C)n4c3)c3ccccc32)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CC[C@H](CO)C5)n4c3)c3ccccc32)cc1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20140315801A1,CCOC(=O)CC(=O)OCC.CCOC(Nc1ccc(Oc2ccnc3cc(-c4ccc(CN(CCOC)C(=O)OC(C)(C)C)cn4)sc23)c(F)c1)C(F)(F)F>>CCOC(=O)C(C(=O)OCC)C(Nc1ccc(Oc2ccnc3cc(-c4ccc(CN(CCOC)C(=O)OC(C)(C)C)cn4)sc23)c(F)c1)C(F)(F)F,,C1CCOC1,,[H-].[Na+],,test
US20100234357A1,C1CC2(CCN1)OCCO2.Cc1c(C)c2c(c(C)c1Br)CC(C)(CI)O2>>Cc1c(C)c2c(c(C)c1Br)CC(C)(CN1CCC3(CC1)OCCO3)O2,,CCOC(C)=O,O,CC(=O)N(C)C,O=C([O-])[O-].[K+].[K+],test
US06111125,C=C1C(C)C[C@@H](O)CC1(C)C>>CC1=C(C)C(C)(C)C[C@@H](O)C1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04806560,C=CC#N.OC(c1ccc(F)cc1)(c1ccccn1)C1CCNCC1>>N#CCCN1CCC(C(O)(c2ccc(F)cc2)c2ccccn2)CC1,,CCO,,,,test
US20090131461A1,CC1CCCC1O.COc1cc2c(Oc3ccc(NC(=O)c4ccccc4)cc3)ccnc2cc1OCC[C@H](NC(=O)OC(C)(C)C)C(=O)O>>COc1cc2c(Oc3ccc(NC(=O)c4ccccc4)cc3)ccnc2cc1OCC[C@H](NC(=O)OC(C)(C)C)C(=O)OC1CCCC1C,CN(C)c1ccncc1,CN(C)C=O,,ClCCCl,,test
US20070225365A1,COc1ccc(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CNC(=O)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>COc1ccc(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CNCCc1cc(C(F)(F)F)cc(C(F)(F)F)c1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20150018332A1,CCN(CC)S(F)(F)F.N#CC1(O)CN(C(c2ccccc2)c2ccccc2)C1>>N#CC1(F)CN(C(c2ccccc2)c2ccccc2)C1,,ClCCl,,O=C([O-])O.[Na+],,test
US20040023933A1,CC(=O)Oc1ccccc1C(=O)Oc1ccc(CO[N+](=O)[O-])nc1C.O=[N+]([O-])O>>CC(=O)Oc1ccccc1C(=O)Oc1ccc(CO[N+](=O)[O-])nc1C.O=[N+]([O-])O,,CC#N,,,,test
US20130267493A1,Fc1ccc(Br)cc1.OCC1COC1>>Brc1ccc(OCC2COC2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US05143928,CSC1=NC(=O)C(=Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)O1.N=C(N)N>>CC(C)(C)c1cc(C=C2OC(NC(=N)N)=NC2=O)cc(C(C)(C)C)c1O,,CCO,,Cl,CC(C)(C)[O-].[K+],test
US20080200485A1,Nc1ccc(S)cc1.O=C(Cl)C1CC1>>O=C(Nc1ccc(S)cc1)C1CC1,,CCOC(C)=O,,c1ccncc1,,test
US04576732,CCCCCCCCOc1ccc(-c2ccc([N+](=O)[O-])cc2)cc1>>CCCCCCCCOc1ccc(-c2ccc(N)cc2)cc1,[Pd],CCOC(C)=O,,[H][H],,test
US20110275637A1,CN1CCNCC1.Cc1cc(COC(=O)Oc2ccc([N+](=O)[O-])cc2)cc(C)n1>>Cc1cc(COC(=O)N2CCN(C)CC2)cc(C)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20130090323A1,Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1I.N#Cc1cncc(B(O)O)c1>>Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1-c1cncc(C#N)c1,,C1COCCO1,O,C1CCC(P(C2CCCCC2)C2CCCCC2)CC1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20150337004A1,CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC[C@@H]2[C@H]4[C@H](C5(C)CC5)CC[C@]4(C(=O)N4CCC[C@H]4c4ncc(-c5cccnc5)[nH]4)CC[C@]23C)C1(C)C>>CC1([C@@H]2CC[C@]3(C(=O)N4CCC[C@H]4c4ncc(-c5cccnc5)[nH]4)CC[C@]4(C)[C@H](CC[C@@H]5[C@@]6(C)CC[C@H](O)C(C)(C)[C@@H]6CC[C@]54C)[C@@H]23)CC1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04067720,CCOc1nc(O)ns1.O=C=NC(=O)CCl>>CCOc1nc(=O)n(C(=O)NC(=O)CCl)s1,,c1ccccc1,,,,test
US20090197859A1,CC(C)(C)OC(=O)c1cccc(C2CCN(Cc3ccccc3)C2)n1>>CC(C)(C)OC(=O)c1cccc(C2CCNC2)n1,[Pd],CO,,O=C[O-].[NH4+],,test
US20090082343A1,CC(C)(C)OC(=O)CCOCCCc1ccnc(-c2nc(=O)c3ccccc3s2)c1>>O=C(O)CCOCCCc1ccnc(-c2nc(=O)c3ccccc3s2)c1,,O=C(O)C(F)(F)F,,,,test
US20090215743A1,C=CCN1C(=O)C(CC(=O)OCC)OC(c2ccccc2OC)c2cc(Cl)ccc21>>CCOC(=O)CC1OC(c2ccccc2OC)c2cc(Cl)ccc2NC1=O,Cl[Pd]Cl,CC(=O)O,,,,test
US20100216788A1,CCOC(=O)c1cccc(I)c1.O=[N+]([O-])c1ccc2[nH]ccc2c1>>CCOC(=O)c1cccc(-n2ccc3cc([N+](=O)[O-])ccc32)c1,[Cu]I,O,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20080318947A1,CCn1c(-c2nonc2N)nc2c(Cl)nc(CO)cc21.O=C1NC(=O)c2ccccc21>>CCn1c(-c2nonc2N)nc2c(Cl)nc(CN3C(=O)c4ccccc4C3=O)cc21,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070249670A1,COC(=O)[C@H](COC(C)(C)C)NC(=O)c1sc(-c2ccc(OC)cc2)cc1NC(=O)Nc1c(C)cc(C)cc1C>>COc1ccc(-c2cc(NC(=O)Nc3c(C)cc(C)cc3C)c(C(=O)N[C@@H](COC(C)(C)C)C(=O)O)s2)cc1,,C1CCOC1,,[Li+].[OH-],,test
US20110124634A1,Cc1[nH]c(C=O)c(C)c1C(=O)CCl.OCCN1CCCC1>>Cc1[nH]c(C=O)c(C)c1C(=O)COCCN1CCCC1,,CC(C)(C)O,,CC(C)(C)[O-].[K+],,test
US20120270867A1,C[Si](C)(C)C#Cc1cc(N)ccc1F>>C#Cc1cc(N)ccc1F,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20070060629A1,CNCCNS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(C)cc2)cc1.COC(=O)Cl>>COC(=O)N(C)CCNS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(C)cc2)cc1,,c1ccncc1,,,,test
US20090137557A1,Cc1nc(-c2ccccc2OCc2ccccc2)n(CCc2ccccc2)c(=O)c1-c1cc2ccccc2s1>>Cc1nc(-c2ccccc2O)n(CCc2ccccc2)c(=O)c1-c1cc2ccccc2s1,[Pd],CCO,,,,test
US20030114390A1,BrCCc1ccccc1.COc1ccc(Br)cc1C=O>>CCc1ccc(C(O)c2cc(Br)ccc2OC)cc1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20150259354A1,NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c3c([nH]c12)CN(Cc1ccccc1)CC3>>NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c3c([nH]c12)CNCC3,[Pd],CO,,,,test
US20100041726A1,CCn1ncc(C)c1-c1csc(C(=O)O)c1.N[C@@H](Cc1cccc(C(F)(F)F)c1)CN1C(=O)c2ccccc2C1=O>>CCn1ncc(C)c1-c1csc(C(=O)N[C@@H](Cc2cccc(F)c2)CN2C(=O)c3ccccc3C2=O)c1,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20080070903A1,C/C(N)=C/C(=O)OCCC#N.CC(=O)CC(=O)OCCC(c1ccccc1)c1ccccc1.O=Cc1cccc(Cl)c1>>CC1=C(C(=O)OCCC#N)C(c2cccc(Cl)c2)C(C(=O)OCCC(c2ccccc2)c2ccccc2)=C(C)N1,,CC(C)O,,,,test
US20130059834A1,CC(C)(C)OC(=O)NCC1(NC(=O)OCc2ccccc2)CC1>>CC(C)(C)OC(=O)NCC1(N)CC1,[Pd],CO,,,,test
US20130123338A1,CCCCC/C=C\C/C=C\CCCCCCCCC(CCCCCCCC/C=C\C/C=C\CCCCC)OC(=O)N(C)CCCOS(C)(=O)=O.CCNC>>CCCCC/C=C\C/C=C\CCCCCCCCC(CCCCCCCC/C=C\C/C=C\CCCCC)OC(=O)N(C)CCCN(C)CC,,CCO,ClCCl,,,test
US05037841,CC(C)(C)OC(=O)N1CCC(O)C1.ClCc1cccc2ccccc12>>CC(C)(C)OC(=O)N1CCC(OCc2cccc3ccccc23)C1,,CS(C)=O,,[H-].[Na+],[Cl-].[NH4+],test
US05773463,CC(C)(C)OC(=O)N[C@H]1Cc2ccccc2[C@H]1Oc1cccc(-c2ccccc2)c1.Cl>>CN[C@H]1Cc2ccccc2[C@H]1Oc1cccc(-c2ccccc2)c1.Cl,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20020028748A1,CCCCNCCS.Cn1c(C(F)(F)F)cc(=O)n(-c2ccc3snc(C=O)c3c2)c1=O>>CCCCN1CCSC1c1nsc2ccc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)cc12,,C1CCOC1,,CCO,,test
US20090312310A1,C=CCOCC=O.O.O=C1CN[C@@H](c2ccccc2)CO1.c1ccccc1>>O=C1OC[C@H](c2ccccc2)N2[C@@H]3COC[C@@H]3C[C@@H]12,,c1ccccc1,,,,test
US20010053788A1,NCCN1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1.O=S(=O)(Cl)c1cccc(C(F)(F)F)c1>>O=S(=O)(NCCN1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)c1cccc(C(F)(F)F)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20120059028A1,CCCC(C(=O)OC)c1c(C)nc2sc3c(c2c1-c1cccc(C(F)(F)F)c1)CCCC3>>CCCC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1cccc(C(F)(F)F)c1)CCCC3,,CO,,[Na+].[OH-],,test
US04337201,CCOP(=O)(CCCCc1ccccc1)CC(=O)O.COC(=O)[C@@H]1CC(O)CN1>>CCOP(=O)(CCCCc1ccccc1)CC(=O)N1CC(O)C[C@H]1C(=O)OC,,CC#N,CCOC(C)=O,O=C(n1ccnc1)n1ccnc1,,test
US20100278833A1,COC(=O)c1sc(-n2cnc3ccncc32)cc1O.Fc1ccc(CBr)c(C(F)(F)F)c1>>COC(=O)c1sc(-n2cnc3ccncc32)cc1OCc1ccc(F)cc1C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060235043A1,CC(C)(C)OC(=O)Nc1ccc2c(-c3ccnc(NC4CCCC4)n3)c(-c3ccc(F)cc3)nn2c1.Cl.ClCCl>>Cl.Cl.Nc1ccc2c(-c3ccnc(NC4CCCC4)n3)c(-c3ccc(F)cc3)nn2c1,,CCOCC,ClCCl,,,test
US20140018313A1,COC(=O)NC(CC1CCOCC1)C(=O)OC>>COC(=O)NC(CC1CCOCC1)C(=O)O,,C1CCOC1,CO,[Li+].[OH-],,test
US05240916,CC(C)(C)c1ccc(CCN)cc1.Clc1ccnc2cccnc12>>CC(C)(C)c1ccc(CCNc2ccnc3cccnc23)cc1,,O,,[NH4+].[OH-],,test
US04551529,NC1=NC(=O)C2=[N+]([O-])C=NC2=N1>>NC1=NC(=O)C2=[N+]([O-])C=NC2=N1,,CC(=O)O,,[Na],,test
US20100137313A1,COc1ncc(Br)cc1C(=O)O.CS(N)(=O)=O>>COc1ncc(Br)cc1C(=O)NS(C)(=O)=O,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20030119787A1,CCOC(=O)C=C1CCP(c2ccccc2)C1(c1ccccc1)c1ccccc1.O=Cc1ccc([N+](=O)[O-])cc1>>CCOC(=O)C=Cc1ccc([N+](=O)[O-])cc1,,ClCCl,,,,test
US20110112147A1,CCOC(=O)CN(Nc1c(COc2ccc(-c3cc(F)c(F)cc3OC)cc2)cccc1C(=O)OC)C(=O)OC(C)(C)C>>COc1cc(F)c(F)cc1-c1ccc(OCc2cccc3c(=O)n(CC(=O)O)[nH]c23)cc1,,C1CCOC1,,Cl,,test
US20150225412A1,C[C@H](NCc1ccc(NC2CCCN(C(=O)OC(C)(C)C)C2)c([N+](=O)[O-])c1)C(C)(C)C.O=C(Cl)OCc1ccccc1>>C[C@H](N(Cc1ccc(NC2CCCN(C(=O)OC(C)(C)C)C2)c([N+](=O)[O-])c1)C(=O)OCc1ccccc1)C(C)(C)C,,C1COCCO1,O,Cl,[Na+].[OH-],test
US20110237791A1,COc1nc(Br)ccc1C=CC(=O)OC(C)(C)C>>COc1nc(Br)ccc1CCC(=O)OC(C)(C)C,[Pt],CCOC(C)=O,,[H][H],,test
US20050148624A1,COC(=O)c1[nH]c(=O)c2ccc(Br)cc2c1-c1ccccc1.COC(=O)c1cccc(CBr)c1>>COC(=O)c1cccc(Cn2c(C(=O)OC)c(-c3ccccc3)c3cc(Br)ccc3c2=O)c1,,CN(C)C=O,,[H-].[Na+],,test
US20130035320A1,CC(=O)OCC(=O)C1=CC[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C.C[Si](C)(C)CN(COCN(Cc1ccccc1)C[Si](C)(C)C)Cc1ccccc1>>CC(=O)OCC(=O)[C@@]12CN(Cc3ccccc3)C[C@@H]1C[C@H]1[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]12C,,C1COCCO1,,,,test
US20120101136A1,CCc1cc(OCCCCBr)ccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1.CN>>CCc1cc(OCCCCNC)ccc1-c1noc(-c2ccc(OC(C)C)c(C#N)c2)n1,,C1CCOC1,,,,test
US20130190312A1,Cc1cc(Sc2cnccn2)cc(C)c1C(=O)CBr.NC(N)=S>>Cc1cc(Sc2cnccn2)cc(C)c1-c1csc(N)n1,,CCO,,,,test
US04059434,O=P(Cl)(Cl)Cl.O=c1c2c([nH]n1-c1ccc(Cl)cc1F)CCCC2>>Fc1cc(Cl)ccc1-n1nc2c(c1Cl)CCCC2,,ClC(Cl)Cl,,,,test
US20110065766A1,CC(C)(C)OC(=O)NC12CC3CC(C1)C(=NO)C(C3)C2.Cl>>Cl.NC12CC3CC(C1)C(=NO)C(C3)C2,,C1COCCO1,,,,test
US20100036054A1,BrP(Br)Br.CCOC(=O)c1cc(CO)cc(C(=O)OCC)c1>>CCOC(=O)c1cc(CBr)cc(C(=O)OCC)c1,,C1CCOC1,,ClCCl,,test
US04419352,CCOC(=O)c1cc(=O)c2c(ccc3nc(C(=O)OC)cc(O)c32)o1.O=S(Cl)Cl>>CCOC(=O)c1cc(=O)c2c(ccc3nc(C(=O)OC)cc(Cl)c32)o1,CN(C)C=O,CC(Cl)Cl,,,,test
US20140315220A1,C#CCOc1cc(C(=O)N(C)Cc2c3ccccc3c(CN(C)C(=O)OC(C)(C)C)c3ccccc23)ccc1C(=O)N(C)Cc1c2ccccc2c(CN(C)C(=O)OC(C)(C)C)c2ccccc12>>C#CCOc1cc(C(=O)N(C)Cc2c3ccccc3c(CNC)c3ccccc23)ccc1C(=O)N(C)Cc1c2ccccc2c(CNC)c2ccccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US05288896,CC(C)(C)c1cc(C(NO)c2ccccc2)cc(C(C)(C)C)c1O.CCN=C=O>>CCNC(=O)N(O)C(c1ccccc1)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1,,Cc1ccccc1,,,,test
US20140350006A1,CI.FC(F)(F)c1cc(Br)nc2[nH]nc(-c3ccccc3)c12>>Cn1nc(-c2ccccc2)c2c(C(F)(F)F)cc(Br)nc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100317582A1,CCOC(=O)c1c(C)ncn1C1C=CC(OC(C)=O)C1>>CCOC(=O)c1c(C)ncn1[C@@H]1C=C[C@@H](O)C1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20110034454A1,CNCc1ccccc1.ClCc1cc(N2CCOCC2)nc(-c2ccccn2)n1>>CN(Cc1ccccc1)Cc1cc(N2CCOCC2)nc(-c2ccccn2)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US06197973B1,CON.Cn1nc(-c2cc(C=C(Cl)C(=O)Cl)c(Cl)cc2F)c(Cl)c1OC(F)F>>CONC(=O)C(Cl)=Cc1cc(-c2nn(C)c(OC(F)F)c2Cl)c(F)cc1Cl,,Cc1ccccc1,O,Cl,O=C([O-])[O-].[K+].[K+],test
US06211199B1,COc1cc(C(=O)N2CCC(CCN3CCC(Nc4nc5ccccc5[nH]4)CC3)(c3ccccc3)C2)cc(OC)c1OC.CS(=O)(=O)O>>COc1cc(C(=O)N2CCC(CCN3CCC(Nc4nc5ccccc5[nH]4)CC3)(c3ccccc3)C2)cc(OC)c1OC.CS(=O)(=O)O,,CCOC(C)=O,,,,test
US20160168096A1,BrC1CCCC1.CCOC(=O)CCCOc1ccc(-c2cccc(O)c2)nc1>>CCOC(=O)CCCOc1ccc(-c2cccc(OC3CCCC3)c2)nc1,,CN(C)C=O,,[H-].[Na+],,test
US20050014723A1,CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)O)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)COP(=O)(O)O,,ClCCl,,[Na+].[OH-],,test
US20060030595A1,COc1cccc(C(Cl)c2cccc(Br)n2)n1.c1cncc(Cc2cccnc2)c1>>COc1cccc(C(c2cccc(Br)n2)C(c2cccnc2)c2cccnc2)n1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20090275583A1,BrCCCBr.C=C(C)[C@@H]1CC[C@]2(C(=O)NCCc3cccc(C(=O)NCc4ccc(O)c(C(=O)OC)c4)c3)CC[C@]3(C)C(CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C12>>C=C(C)[C@@H]1CC[C@]2(C(=O)NCCc3cccc(C(=O)NCc4ccc(OCCCBr)c(C(=O)OC)c4)c3)CC[C@]3(C)C(CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040006099A1,CCOC(=O)C1(COc2ccc3c(c2)CN(C(=O)OCc2ccccc2)CC3)CCNCC1.Clc1ccnc(Cl)n1>>CCOC(=O)C1(COc2ccc3c(c2)CN(C(=O)OCc2ccccc2)CC3)CCN(c2ccnc(Cl)n2)CC1,,CCO,,CCN(CC)CC,O,test
US20050256132A1,COC(=O)/C(C#N)=C/c1ccnc2ccccc12.COc1ccccc1[Mg]Br>>COC(=O)C(C#N)C(c1ccccc1OC)c1ccnc2ccccc12,,C1CCOC1,,,,test
US20110034454A1,CCOC(=O)CC(=O)OCC.CS(=O)(=O)CC(=N)N>>CS(=O)(=O)Cc1nc(O)cc(O)n1,,CCOCC,,O=C([O-])[O-].[K+].[K+],,test
US20050154056A1,NCc1ccccn1.O=C(Nc1ccccc1OS(=O)(=O)c1ccc(C(F)(F)F)cc1)Oc1ccc([N+](=O)[O-])cc1>>O=C(NCc1ccccn1)Nc1ccccc1OS(=O)(=O)c1ccc(C(F)(F)F)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20140315902A1,COc1cc(OC)c(F)c(N(Cc2cnc(Cl)c(C#N)c2Cl)C(=O)Cl)c1F.NCC1CC1>>COc1cc(OC)c(F)c(N(Cc2cnc(Cl)c(C#N)c2Cl)C(=O)NCC2CC2)c1F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110251181A1,CC(=O)OC1C[C@@H](C)c2c(Cl)ncnc21>>C[C@@H]1CC(O)c2ncnc(Cl)c21,,O,,C1CCOC1,[Li+].[OH-],test
US20160095858A1,CC1CNC(C)(C)C1.Nc1cccc(S(=O)(=O)NC(=O)c2ccc(Cl)nc2Cl)n1>>CC1CN(c2nc(Cl)ccc2C(=O)NS(=O)(=O)c2cccc(N)n2)C(C)(C)C1,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US05929097,BrCc1ccccc1.COc1ccc(S(=O)(=O)Nc2c(C#N)cc(C)cc2C(=O)O)cc1>>COc1ccc(S(=O)(=O)Nc2c(C(=O)O)cc(C)c(Cc3ccccc3)c2C#N)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040102634A1,CCCOC(Cc1ccc(OC)c(N=C=O)c1)C(=O)OCC.OCc1ccc(Cl)cc1Cl>>COc1ccc(CC(OC(C)C)C(=O)O)cc1NC(=O)OCc1ccc(Cl)cc1Cl,,C1CCOC1,,c1ccncc1,,test
US05885999,CC(C)(C)OC(=O)N1CCC(CN(c2ccccc2)S(C)(=O)=O)CC1.Cl>>CS(=O)(=O)N(CC1CCNCC1)c1ccccc1.Cl,,CO,,,,test
US06177449B1,CCS(=O)(=O)NC1CC(C)(C)Oc2ccc(OCc3ccccc3)cc21.CI>>CCS(=O)(=O)N(C)C1CC(C)(C)Oc2ccc(OCc3ccccc3)cc21,,CC(=O)N(C)C,,[H-].[Na+],,test
US20120232083A1,C[C@@](CCn1cc(F)c(-c2ccc(Cl)cc2F)cc1=O)(C(=O)NOC1CCCCO1)S(C)(=O)=O>>C[C@@](CCn1cc(F)c(-c2ccc(Cl)cc2F)cc1=O)(C(=O)NO)S(C)(=O)=O,,CCO,,Cl,O,test
US20120225854A1,C[C@H]1COCCN1C[C@H]1CN(S(=O)(=O)c2ccc([N+](=O)[O-])s2)CCN1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1>>C[C@H]1COCCN1C[C@H]1CN(S(=O)(=O)c2ccc(N)s2)CCN1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1,[Fe],CC(=O)O,,O=C([O-])O.[Na+],,test
US20120029190A1,CC1CC(N)C(O)CN1C(=O)OCc1ccccc1.O=C(O)c1ccccn1>>CC1CC(NC(=O)c2ccccn2)C(O)CN1C(=O)OCc1ccccc1,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20070213341A1,CCOC(=O)Cl.O=C1Nc2cc(Cl)ccc2/C1=C/c1cccc(Cl)c1>>CCOC(=O)N1C(=O)/C(=C\c2cccc(Cl)c2)c2ccc(Cl)cc21,,ClCCl,,CCN(CC)CC,Cl,test
US20130109682A1,C=C[C@H]1OC(c2ccncc2[N+](=O)[O-])=C[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>C=C[C@H]1OC(c2ccncc2[N+](=O)[O-])=C[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H]1OS(=O)(=O)C(F)(F)F,CN(C)c1ccncc1,ClCCl,O,c1ccncc1,,test
US20080306084A1,CNC.COc1ccc(CN2CCC(C=O)CC2)cc1.[C-]#N>>COc1ccc(CN2CCC(C(C#N)N(C)C)CC2)cc1,,CO,O,Cl,,test
US20090291942A1,CCc1nc2c(C)cc(C)nc2n1Cc1ccc(/C=C/CCO)cc1>>CCc1nc2c(C)cc(C)nc2n1Cc1ccc(CCCCO)cc1,[Pd],C1CCOC1,,,,test
US20130303509A1,CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc(NC(=O)C3CNC3)cc2)CC1.Clc1cnnc(Cl)c1Cl>>CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc(NC(=O)C3CN(c4cnnc(Cl)c4Cl)C3)cc2)CC1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,,test
US03996361,CCCN.Clc1ncnc2c1ncn2CCCN1CCN(c2ccccc2)CC1>>CCCNc1ncnc2c1ncn2CCCN1CCN(c2ccccc2)CC1,,CCCO,,,,test
US05519138,CCCCc1nc2ccccc2n1Cc1ccc(OCCC2CCCCC2C(=O)OC)cc1>>CCCCc1nc2ccccc2n1Cc1ccc(OCCC2CCCCC2C(=O)O)cc1,,CCO,,[Na+].[OH-],,test
US04537892,Cc1ccc(S(=O)(=O)O)cc1.Cc1ccccc1.c1ccccc1>>c1csc(C2CCCCC2)c1,,Cc1ccccc1,,,,test
US20090312321A1,CCONC(=O)c1cc(OC)cc([N+](=O)[O-])c1>>CCONC(=O)c1cc(N)cc(OC)c1,[Pd],CO,,[H][H],,test
US20090156593A1,c1ccc(CC2(N3CCOCC3)CCC3(CC2)OCCO3)cc1>>O=C1CCC(Cc2ccccc2)(N2CCOCC2)CC1,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20070161686A1,COc1cc(N)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1.CS(=O)(=O)Cl>>COc1cc(NS(C)(=O)=O)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1,CN(C)c1ccncc1,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20130184257A1,C1CCNC1.CS(=O)(=O)c1ccc(N[C@H]2CCN(C3CCN(c4noc(C(Cl)(Cl)Cl)n4)CC3)C2=O)c(F)c1>>CS(=O)(=O)c1ccc(N[C@H]2CCN(C3CCN(c4noc(N5CCCC5)n4)CC3)C2=O)c(F)c1,,CCO,,,,test
US20040127530A1,C1NCC2CC12.O=[N+]([O-])c1cc(F)c(F)c(F)c1>>O=[N+]([O-])c1cc(F)c(N2CC3CC3C2)c(F)c1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,Cl,test
US20100216750A1,CNc1ccccc1.O=C(CCCCCBr)c1ncc(-c2ccccn2)o1>>CN(CCCCCC(=O)c1ncc(-c2ccccn2)o1)c1ccccc1,,ClCCl,,,,test
US20110136764A1,CCOP(OCC)OCC.CN1Cc2c(C3=CCC(=O)CC3)ccc([N+](=O)[O-])c2C1=O>>CCOP(=O)(OCC)C1(O)CC=C(c2ccc([N+](=O)[O-])c3c2CN(C)C3=O)CC1,,ClCCl,,CCOCC,Cl,test
US20130190332A1,COC(=O)c1ccc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)n2c1.N>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4ccc(C(N)=O)cn4c3-c3ccccc3)cc2)CCC1,,CO,,,,test
US20100204240A1,COC(=O)CCSc1cnc(Nc2nc([C@H]3COC4(CCCCC4)O3)ns2)c(Oc2cccnc2C)c1.COCCBr>>COCCSc1cnc(Nc2nc([C@H]3COC4(CCCCC4)O3)ns2)c(Oc2cccnc2C)c1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20040053979A1,CCOC(=O)/C(=C/c1ccc2[nH]ccc2c1)OCC>>CCOC(=O)C(Cc1ccc2[nH]ccc2c1)OCC,[Pd],CCO,,[H][H],,test
US20050107354A1,CCOC(=O)COc1cc(C(C)C)ccc1CCNS(=O)(=O)c1cc(C#N)ccc1O.NN>>CC(C)c1ccc(CCNS(=O)(=O)c2cc(C#N)ccc2O)c(OCC(=O)NN)c1,,CCO,,O,,test
US05672584,CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)O.OCC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)OCC(Cl)(Cl)Cl,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20030216428A1,CC(C)(C)OC(=O)NCC(C)(C)C1CC(N2C(=O)c3ccccc3C2=O)c2cc([N+](=O)[O-])ccc2N1>>CC(C)(CN)C1CC(N2C(=O)c3ccccc3C2=O)c2cc([N+](=O)[O-])ccc2N1,,C1CCOC1,,Cl,,test
US20160257651A1,CC1c2ccc(Br)cc2CN1C(=O)C(C)(C)C>>CC1NCc2cc(Br)ccc21,,Cl,,[Na+].[OH-],,test
US20150376160A1,CCOC(=O)C1(c2ccc(-c3ccc(-c4sc(Cl)cc4C(=O)OCc4ccccc4)cc3)cc2)CC1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4sc(Cl)cc4C(=O)O)cc3)cc2)CC1,,ClCCl,,BrB(Br)Br,,test
US09067898B1,CCOC(=O)c1c(Cl)nsc1C1=CCC(C)CC1>>CC1CC=C(c2snc(Cl)c2CO)CC1,,Cc1ccccc1,,CC(C)C[AlH]CC(C)C,,test
US20110160231A1,COC(=O)c1ccc(C)cc1N.COc1ccccc1N=C=S>>COc1ccccc1-n1c(S)nc2cc(C)ccc2c1=O,,CCO,,CC(=O)O,,test
US20020028814A1,CCC(C)(C)C(=O)C(=O)C1CCCNN1Cc1ccccc1>>CCC(C)(C)C(=O)C(=O)C1CCCNN1,[Pd],CCO,,,,test
US20030120079A1,C1CCOC1.CCOC(=O)c1ccc(CCN)cc1>>CCCCCC.CCOC(C)=O,,C1CCOC1,,,,test
US20110144105A1,CC(C)(OC1CCCCO1)c1ccc(C(CC2CCCC2)c2cc3cc(C(=O)O)cnc3[nH]2)cc1F>>CC(C)(O)c1ccc(C(CC2CCCC2)c2cc3cc(C(=O)O)cnc3[nH]2)cc1F,,CCO,,,,test
US20150141406A1,COc1nccc2c1c(-c1ccc(N3CCNCC3)cc1)nn2-c1c(F)cccc1F.CS(=O)(=O)Cl>>COc1nccc2c1c(-c1ccc(N3CCN(S(C)(=O)=O)CC3)cc1)nn2-c1c(F)cccc1F,,ClCCl,,CCN(CC)CC,,test
US20160096827A1,N#Cc1cc(-c2ncnc(Nc3ccc(N4CCN(C5CCOCC5)CC4)cc3)n2)ccc1O[C@H]1CCNC[C@H]1F.O=C(O)CO>>N#Cc1cc(-c2ncnc(Nc3ccc(N4CCN(C5CCOCC5)CC4)cc3)n2)ccc1O[C@H]1CCN(C(=O)CO)C[C@H]1F,,ClCCl,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05889010,CC(CO)CNc1ccc(F)cc1[N+](=O)[O-].CS(=O)(=O)OS(C)(=O)=O>>CC(CNc1ccc(F)cc1[N+](=O)[O-])COS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20060135530A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)Cc1nc2ccc(Br)cc2c(-c2ccccc2)c1CN>>CC(C)Cc1nc2ccc(Br)cc2c(-c2ccccc2)c1CNC(=O)OC(C)(C)C,,CCOC(C)=O,,,,test
US20070249670A1,CC(C)(C)OC(=O)c1cc(Br)sc1N.Cc1cc(C)c(N=C=O)c(C)c1>>Cc1cc(C)c(NC(=O)Nc2sc(Br)cc2C(=O)OC(C)(C)C)c(C)c1,,CN(C)C=O,,CCN(CC)CC,,test
US20130143876A1,CCOc1ccc(N2CCC(c3ccc(C(C)C(=O)O)cc3)CC2)cc1.NC1CC1>>CCOc1ccc(N2CCC(c3ccc(C(C)C(=O)NC4CC4)cc3)CC2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20110144091A1,CI.O=C(N[C@@H]1CCc2ccccc2NC1=S)OCc1ccccc1>>CSC1=Nc2ccccc2CC[C@H]1NC(=O)OCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20100179322A1,CN1C(=O)c2ccccc2CC1OCCCN1CCN(c2cccc3sccc23)CC1.O=C(O)/C=C\C(=O)O>>CN1CCc2ccc(OCCCN3CCN(c4cccc5sccc45)CC3)cc2C1=O.O=C(O)/C=C\C(=O)O,,CO,ClCCl,,,test
US20100016401A1,COC(=O)c1cccc2oc(C)cc12>>Cc1cc2c(C(=O)O)cccc2o1,,CO,O,[Na+].[OH-],,test
US20140371199A1,C1CC(N2CCOCC2)CCN1.N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)O)cc4)cn23)cc1>>N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)N5CCC(N6CCOCC6)CC5)cc4)cn23)cc1,,CN(C)C=O,O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06340687B1,CCOC(C)=O.Cc1cc(Cl)ccc1NCCCNC(C)C.Cc1ccc(S(=O)(=O)O)cc1>>Cc1cc(Cl)ccc1N1CCCN(C(C)C)C1=S,,C1COCCO1,CCOC(C)=O,O,,test
US20090137603A1,CCOC(=O)c1nc2ccccc2c(=O)[nH]1.NCc1cccc(OCCCOc2ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)n2)c1>>O=C(NCc1cccc(OCCCOc2ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)n2)c1)c1nc2ccccc2c(=O)[nH]1,,CCO,,CCN(C(C)C)C(C)C,,test
US20120142717A1,CSc1nc(=O)c(Cc2cnc(C)nc2)c[nH]1.N#Cc1cc(CCN)ccc1Oc1ccc(C(F)(F)F)cn1>>Cc1ncc(Cc2c[nH]c(NCCc3ccc(Oc4ccc(C(F)(F)F)cn4)c(C#N)c3)nc2=O)cn1,,CCO,,,,test
US20150225452A1,COC(=O)c1ccc(COc2ccc(C[C@@H](CO)NC(=O)OC(C)(C)C)cc2)cc1>>COC(=O)c1ccc(COc2ccc(C[C@@H](C=O)NC(=O)OC(C)(C)C)cc2)cc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20050113388A1,N.O=C(NCCCCc1ccc(OCC2CO2)cc1)OCc1ccccc1>>NCC(O)COc1ccc(CCCCNC(=O)OCc2ccccc2)cc1,,CCO,,,,test
US20120214848A1,CC(C)O.CC(C)Oc1ccc(-c2noc(-c3ccc(C(C)(C)NCCC(=O)O)cc3)n2)cc1Cl>>CC(C)O.CC(C)Oc1ccc(-c2noc(-c3ccc(C(C)(C)NCCC(=O)O)cc3)n2)cc1Cl,,CC(C)O,,,,test
US20150111870A1,COc1nc2c(C)cc(C(O)c3c(C)nn(C)c3C)cc2c(Cl)c1OCc1ccccc1>>COc1nc2c(C)cc(C(=O)c3c(C)nn(C)c3C)cc2c(Cl)c1OCc1ccccc1,O=[Mn]=O,ClCCl,,,,test
US20040063680A1,CCOC(=O)C(C(=O)OCC)c1ccc(Br)cc1[N+](=O)[O-]>>CCOC(=O)Cc1ccc(Br)cc1[N+](=O)[O-],,CCO,,Cl,O,test
US20120053218A1,COC(=O)CCl.O=c1[nH]nc(-c2ccccc2OC(F)(F)F)n1C1CC1>>COC(=O)Cn1nc(-c2ccccc2OC(F)(F)F)n(C2CC2)c1=O,,CC#N,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070078184A1,BrCc1ccccc1.Cc1c(OCCO)ccc(-c2ccc(C(=O)O)cc2)c1C>>Cc1c(OCCO)ccc(-c2ccc(C(=O)OCc3ccccc3)cc2)c1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110295017A1,Brc1ccc(-c2ccccc2)c2c3c(c(-c4ccccc4)cc12)-c1cccc2cccc-3c12.CCOB(OCC)OCC>>OB(O)c1ccc(-c2ccccc2)c2c3c(c(-c4ccccc4)cc12)-c1cccc2cccc-3c12,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US20100135999A1,CCOC(=O)c1cc(OCC(=O)N2C[C@@H](O)C[C@H]2C(=O)NC2CCC2)c2ccc(C)cc2n1>>Cc1ccc2c(OCC(=O)N3C[C@@H](O)C[C@H]3C(=O)NC3CCC3)cc(C(=O)O)nc2c1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20030186989A1,C=CCBr.C[C@@H](N)c1ccc(Br)cc1.Cc1ccccc1>>C=CCN(CC=C)[C@H](C)c1ccc(Br)cc1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20050065340A1,C1CCNC1.COc1cc(-c2nc3ccccc3o2)ccc1CBr>>COc1cc(-c2nc3ccccc3o2)ccc1CN1CCCC1,,ClCCl,,CCN(CC)CC,,test
US20050004232A1,CC(C)(C)[Si](C)(C)Cl.CC1(C)OC(=O)[C@H](CC(=O)O)O1>>CC1(C)OC(=O)C(CC(=O)O[Si](C)(C)C(C)(C)C)O1,,CN(C)C=O,Cc1ccccc1,c1c[nH]cn1,,test
US20020156281A1,CCN(CC)CCCc1ccc([N+](=O)[O-])cc1.O=C(Cl)c1ccccc1>>CCN(CC)CCCc1ccc(NC(=O)c2ccccc2)cc1,,ClCCl,c1ccncc1,,,test
US04053618,C/C=C(/C(=O)OCC)P(=O)(OCC)OCC.Cc1ncc(C=O)s1>>CCOC(=O)C=CC=Cc1cnc(C)s1,,C1CCOC1,CCOCC,O,[H-].[Na+],test
US20140171431A1,CBr.CN(C)Cc1nnc(Cn2c(SCc3ccc(F)cc3)nc(=O)c3c2CCC3)n1Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1>>C[N+](C)(C)Cc1nnc(Cn2c(SCc3ccc(F)cc3)nc(=O)c3c2CCC3)n1Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1.[Br-],,CC(C)=O,,,,test
US20050065151A1,COc1cnc(C2CCOCC2)c2sc(N)nc12.O=C(Cl)Oc1ccccc1.OCC1CCNCC1>>COc1cnc(C2CCOCC2)c2sc(NC(=O)N3CCC(CO)CC3)nc12,,C1CCOC1,ClCCl,c1ccncc1,,test
US05420309,O=[N+]([O-])c1cc2c(cc1[N+](=O)[O-])OC(CC(F)(F)F)(C(F)(F)F)O2>>Nc1cc2c(cc1N)OC(CC(F)(F)F)(C(F)(F)F)O2,,C1CCOC1,,[H][H],,test
US20160009683A1,C[Si](C)(C)c1c(F)cccc1OC(F)(F)F.II>>C[Si](C)(C)c1c(F)ccc(I)c1OC(F)(F)F,,C1CCOC1,,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US20150048279A1,CC(C)[Si](OS(=O)(=O)C(F)(F)F)(C(C)C)C(C)C.c1ccsc1>>CC(C)[Si](c1cccs1)(C(C)C)C(C)C,,C1CCOC1,,[Li]CCCC,,test
US04803200,COC(C(=O)c1ccccc1)c1ccccc1.NCCO>>COC(C(=NCCO)c1ccccc1)c1ccccc1,,CO,,O,,test
US20120252740A1,COC(=O)c1ccc(CBr)cc1.c1ccc2c(c1)[nH]c1ccccc12>>COC(=O)c1ccc(Cn2c3ccccc3c3ccccc32)cc1,,O,,CN(C)C=O,[H-].[Na+],test
US20160194316A1,CCN(c1cc(Cl)cc(C(=O)NCc2c(OC)nn(C)c2C)c1C)[C@@H]1CC[C@@H](N(C)Cc2cccnc2)CC1>>CCN(c1cc(Cl)cc(C(=O)NCc2c(C)n(C)[nH]c2=O)c1C)[C@@H]1CC[C@@H](N(C)Cc2cccnc2)CC1,,Cl,,O=C([O-])O.[Na+],,test
US20030191126A1,COC(=O)c1ccccc1CBr.COc1ccc(Br)c(CC2CCN(CCCN)CC2)c1>>COc1ccc(Br)c(CC2CCN(CCCN3Cc4ccccc4C3=O)CC2)c1,,CCOC(C)=O,Cc1ccccc1,CCN(CC)CC,,test
US20100190747A1,CCCI.O=c1c2cc[nH]c2[nH]c(=S)n1-c1ccc(OCC(F)(F)F)cc1>>CCCSc1nc2[nH]ccc2c(=O)n1-c1ccc(OCC(F)(F)F)cc1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US05702641,FC(F)(F)Oc1ccc(CCC2CCC(C3CCC(CCC4OCCCO4)CC3)CC2)cc1>>O=CCCC1CCC(C2CCC(CCc3ccc(OC(F)(F)F)cc3)CC2)CC1,,Cc1ccccc1,,O=CO,,test
US20040167216A1,CO.C[C@@](Cc1ccc(O)c(O)c1)(NN)C(=O)O>>COC(=O)C(C)(Cc1ccc(O)c(O)c1)NN,,CO,,CC(=O)Cl,,test
US20080051418A1,CCOC(=O)CP(=O)(OCC)OCC.O=Cc1cc(OCc2ccccc2)nn1Cc1ccccc1>>CCOC(=O)/C=C/c1cc(OCc2ccccc2)nn1Cc1ccccc1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20070249620A1,COc1ccc(C)cc1N=C=O.Cc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1N>>COc1ccc(C)cc1NC(=O)Nc1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)cc1C,,C1CCOC1,,CO,,test
US20030220323A1,COC(=O)CN1CCN(C(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccccc2N)CC1>>Nc1ccccc1C(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCN(CC(=O)O)CC1,,CO,,[K+].[OH-],,test
US06083943,COc1ccc(OC(F)(F)F)cc1C=O.N[C@H]1C[C@H](CO)CN(C(=O)OCc2ccccc2)[C@H]1c1ccccc1>>COc1ccc(OC(F)(F)F)cc1CN[C@H]1C[C@H](CO)CN(C(=O)OCc2ccccc2)[C@H]1c1ccccc1,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20150266881A1,Cc1nnc(NC(=O)c2cccc([C@@H]3C[C@H]3N(CC3CC3)C(=O)OC(C)(C)C)c2)s1.Cl>>Cc1nnc(NC(=O)c2cccc([C@@H]3C[C@H]3NCC3CC3)c2)s1.Cl,,CCOC(C)=O,CO,,,test
US20150080438A1,COc1cccc(C2=C(C#CCCCO)c3ccc(OC)cc3CCC2)c1>>COc1cccc(C2=C(CCCCCO)c3ccc(OC)cc3CCC2)c1,[Pd],C1CCOC1,,,,test
US06713471B1,NCCO.O=C(Cl)c1ccccc1>>O=C(NCCO)c1ccccc1,,C1CCOC1,,,,test
US20050026929A1,COC(=O)C(=O)Cl.N=C(NO)c1ccc(CNC(=O)Cc2ccccc2)cc1.Nc1noc(C2CN3CCC2C3)n1>>O=C(Cc1ccccc1)NCc1ccc(-c2noc(C(=O)N3CCCCC3)n2)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20010014691A1,COc1cncc(O)c1.ClCCCI>>COc1cncc(OCCCCl)c1,,CN(C)C=O,O,[H-].[Na+],,test
US20090004185A1,C[C@H](NC(=O)OC(C)(C)C)c1ccc([N+](=O)[O-])cc1>>C[C@H](NC(=O)OC(C)(C)C)c1ccc(N)cc1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20030166639A1,CCOc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2ccnc(-c3cccnc3)c2)cc1C(F)(F)F>>CCOc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1ccnc(-c3cccnc3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050176689A1,CN(c1cccc(C#C[Si](C)(C)C)c1)C1CC1>>C#Cc1cccc(N(C)C2CC2)c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US08633200B2,CC(=O)OC(C)(C)C.COC(=O)[C@@H](O)c1c(C)nc2cc(-c3cccc(Cl)c3)nn2c1C(C)C>>COC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc(-c3cccc(Cl)c3)nn2c1C(C)C,,CCOCC,ClCCl,[O-][Cl+3]([O-])([O-])O,,test
US20110178091A1,CC(C)(C)[Si](C)(C)OCCCNC(=O)OCc1ccccc1.CI>>CN(CCCO[Si](C)(C)C(C)(C)C)C(=O)OCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20140323480A1,COC(=O)c1cc(N2CCOCC2)nc2[nH]c(C)nc12.Cc1c(Cl)cccc1CBr>>COC(=O)c1cc(N2CCOCC2)nc2c1nc(C)n2Cc1cccc(Cl)c1C,,CN(C)C=O,,O,O=C([O-])[O-].[Na+].[Na+],test
US20100075953A1,ClCCCN1CCCCC1.Oc1ccc(Br)cc1F>>Fc1cc(Br)ccc1OCCCN1CCCCC1,,CCC(C)=O,,[I-].[K+],,test
US20140021405A1,CC=O.Fc1cc(Br)cc(Br)c1Br>>CC(O)c1cc(Br)cc(F)c1Br,,C1CCOC1,,,,test
US20040147543A1,CC(C)(N)CN.O=[N+]([O-])c1cnc2cc(-c3ccccc3)ccc2c1Cl>>CC(C)(N)CNc1c([N+](=O)[O-])cnc2cc(-c3ccccc3)ccc12,,ClCCl,,CCN(CC)CC,,test
US20160251339A1,O=C(N1CCN(c2cc(S(=O)(=O)n3ccc4ccc(Cl)cc43)ccc2OCC(F)(F)C(F)F)CC1)C(Cl)(Cl)Cl>>O=S(=O)(c1ccc(OCC(F)(F)C(F)F)c(N2CCNCC2)c1)n1ccc2ccc(Cl)cc21,,C1CCOC1,,[K+].[OH-],,test
US20080214511A1,CC(C)(C)OC(=O)CN1CC2CCCC(=O)Nc3cccc1c32.CI>>CN1C(=O)CCCC2CN(CC(=O)O)c3cccc1c32,,CN(C)C=O,,[H-].[Na+],,test
US20120302610A1,CCOC(=O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2CNc2ccc(-c3ccc(Cl)cc3Cl)cc2)cn1>>O=C(O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2CNc2ccc(-c3ccc(Cl)cc3Cl)cc2)cn1,,CO,,C1CCOC1,[Na+].[OH-],test
US04929741,C#CCOC(C)OCC.O=Cc1ccc(O)cc1>>CCOC(C)OCC#CC(O)c1ccc(O)cc1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20090203629A1,CC(C)(C)N=C=O.CC(C)(C)[C@H](N)C(=O)N1C[C@H](Oc2ccc(Cl)cn2)C[C@H]1C(=O)N[C@@H](CC1CCC1)C(O)C(=O)NC1CC1>>CC(C)(C)NC(=O)N[C@H](C(=O)N1C[C@H](Oc2ccc(Cl)cn2)C[C@H]1C(=O)N[C@@H](CC1CCC1)C(O)C(=O)NC1CC1)C(C)(C)C,,ClCCl,,CCN(CC)CC,Cl,test
US04762942,CCCCCCCCCCCCCCc1ccc(OCC(COC(c2ccccc2)(c2ccccc2)c2ccccc2)OCc2ccccc2)c(CCCCCC)c1>>CCCCCCCCCCCCCCc1ccc(OCC(CO)OCc2ccccc2)c(CCCCCC)c1,,ClC(Cl)Cl,,,,test
US05721234,CC(=O)NC1Cc2cc(Br)c3[nH]c(=O)c(=O)[nH]c3c2C1>>CC(=O)NC1Cc2ccc3[nH]c(=O)c(=O)[nH]c3c2C1,[Pd],CN(C)C=O,,CC(=O)[O-].[K+],,test
US20100222339A1,CCC(CC)c1cc(C)nc2c(-c3sc(Br)nc3C(F)(F)F)c(C)nn12.CNC>>CCC(CC)c1nc(C)cc2c(-c3sc(N(C)C)nc3C(F)(F)F)c(C)nn12,,CO,,,,test
US20010036946A1,NC1CCN(Cc2ccccc2)CC1.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=[N+]([O-])c1ccccc1S(=O)(=O)NC1CCN(Cc2ccccc2)CC1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US05552557,N#CC#N.NCC(=O)c1ccccc1>>N#Cc1nc(-c2ccccc2)c[nH]1,,CN(C)C=O,,Cl,c1ccncc1,test
US04711903,C=CC=O.CC(C)(C)c1cc(S)cc(C(C)(C)C)c1O>>CC(C)(C)c1cc(SCCC=O)cc(C(C)(C)C)c1O,,CO,,CCN(CC)CC,,test
US20040063170A1,COCCl.Cc1cc(C)c(C=O)c(O)c1>>COCOc1cc(C)cc(C)c1C=O,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20040082571A1,O=C(CCl)N1CCN(c2ccc(F)cc2)CC1.O=[N+]([O-])c1cccc2cn[nH]c12>>O=C(Cn1ncc2cccc([N+](=O)[O-])c21)N1CCN(c2ccc(F)cc2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070060754A1,CCCn1c(COCC)nc2c(N)nc3ccc(OC4CCNCC4)cc3c21.CS(=O)(=O)OS(C)(=O)=O>>CCCn1c(COCC)nc2c(N)nc3ccc(OC4CCN(S(C)(=O)=O)CC4)cc3c21,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20130296298A1,NNc1ccc(Cl)nn1.O=C(O)c1ccccc1F>>Fc1ccccc1-c1nnc2ccc(Cl)nn12,,C1COCCO1,,CCN(CC)CC,,test
US20030092679A1,BrC(Br)(Br)Br.Cc1cnc(NCC(F)(F)c2ccccc2)c(=O)n1CCCO>>Cc1cnc(NCC(F)(F)c2ccccc2)c(=O)n1CCCBr,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US05264607,COC(=O)C(Cc1ccc(C(F)(F)P(=O)(OC(C)(C)C)OC(C)(C)C)cc1)NC(=O)OCc1ccccc1>>COC(=O)C(N)Cc1ccc(C(F)(F)P(=O)(OC(C)(C)C)OC(C)(C)C)cc1,[Pd],CO,,ClC(Cl)Cl,,test
US20050107423A1,CCOC(=O)C1(O[Si](C)(C)C(C)(C)C)CC1.O=C1CCCN1Cc1ccccc1>>CC(C)(C)[Si](C)(C)OC1(C(O)=C2CCN(Cc3ccccc3)C2=O)CC1,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20140243302A1,COc1cc(C)c2ncc([N+](=O)[O-])c(Br)c2n1>>COc1cc(C)c2ncc(N)c(Br)c2n1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20150232445A1,CC(=O)N1c2ccc(Br)c(O)c2CC[C@@H]1C.Cc1ccnc(Cl)c1>>CC(=O)N1c2ccc(Br)c(Oc3cc(C)ccn3)c2CC[C@@H]1C,[Cu]I,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100075965A1,CC(C)(C)OC(=O)N1CCC(O)CC1.Nc1ncc(Br)nc1Br>>CC(C)(C)OC(=O)N1CCC(Oc2nc(Br)cnc2N)CC1,,C1CCOC1,,[H-].[Na+],,test
US20050288340A1,CC(C)(C)c1ccc2oc(CCN3C(=O)c4ccccc4C3=O)nc2c1>>CC(C)(C)c1ccc2oc(CCN)nc2c1,,CCO,,NN,O,test
US06809097B1,COc1cc2c(Cl)ccnc2cc1OCc1ccccc1.Cl.Nc1cc(O)c(Cl)cc1F>>COc1cc2c(Nc3cc(O)c(Cl)cc3F)ccnc2cc1OCc1ccccc1.Cl,,CCC(C)O,,,,test
US20090111794A1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2CCOc1ccc(Oc2nc3ccccc3s2)cc1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.c1ccc2sc(Oc3ccc(OCCN4C[C@@H]5C[C@H]4CN5)cc3)nc2c1,,ClCCl,,,,test
US20060063779A1,Cc1nc(C(F)(F)F)ccc1C(=O)Cl.Nc1ccc(Cl)c(-c2ccccn2)c1>>Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1,,C1CCOC1,,CCOC(C)=O,,test
US20080188506A1,Cc1ccc(F)cc1C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12>>Cc1ccc(F)cc1C1NCCC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12,,CO,,[BH4-].[Na+],,test
US20130059896A1,CCCC(=O)Cl.Nc1ncc(-c2ccnn2-c2c(Cl)cccc2Cl)s1>>CCCC(=O)Nc1ncc(-c2ccnn2-c2c(Cl)cccc2Cl)s1,,C1CCOC1,,CN1CCOCC1,,test
US20130303375A1,C=CC[Sn](CCCC)(CCCC)CCCC.COC(=O)Cc1ccccc1I>>C=CCc1ccccc1CC(=O)OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US05616717,Cc1ccc2oc(Cl)nc2c1.N[C@@H](CC1CCCCC1)c1ccccn1>>Cc1ccc2oc(NC(CC3CCCCC3)c3ccccn3)nc2c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070281922A1,O=S(=O)(Cl)c1cccc2ccccc12.O=[N+]([O-])c1ccc2cn[nH]c2c1>>O=[N+]([O-])c1ccc2cnn(S(=O)(=O)c3cccc4ccccc34)c2c1,,C1CCOC1,,O,CC(C)(C)[O-].[K+],test
US04912258,CC(=O)N1CC1.CCNc1ccc(F)c(C)c1>>CCN(CCNC(C)=O)c1ccc(F)c(C)c1,,CO,,,,test
US20010027196A1,CS(=O)c1nc(N)nc(-n2cccn2)c1C#N.OCc1cc2ccccc2cn1>>N#Cc1c(OCc2cc3ccccc3cn2)nc(N)nc1-n1cccn1,,COCCOC,,C1CCC2=NCCCN2CC1,,test
US20130053444A1,CC(C)(C)S.COC(=O)Cc1ccc(OC)c(Oc2ccc([N+](=O)[O-])cc2CBr)c1>>COC(=O)Cc1ccc(OC)c(Oc2ccc([N+](=O)[O-])cc2CSC(C)(C)C)c1,,O,,C1CCOC1,[H-].[Na+],test
US20120108583A1,Cc1ccc(N)c(C)n1.S=C(Cl)Cl>>Cc1ccc(N=C=S)c(C)n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070072853A1,CC(=O)N(C)c1ccc(NCC2CCOCC2)c(NC(=O)C(C)(F)F)c1>>CC(=O)N(C)c1ccc2c(c1)nc(C(C)(F)F)n2CC1CCOCC1,,CC(=O)O,,,,test
US04876269,CCN(CC)CC.O[C@@H]1Cc2ccccc2[C@H]1N1CCCC1>>CN[C@@H]1c2ccccc2C[C@H]1N1CCCC1,,ClCCl,,CS(=O)(=O)Cl,,test
US20110319406A1,CNC.N#Cc1cccc([N+](=O)[O-])c1CBr>>CN(C)Cc1c(C#N)cccc1[N+](=O)[O-],,ClCCl,,CCN(CC)CC,Cl,test
US20140155415A1,C[C@@](O)(c1ccnc(-c2cccc3cc([C@H](N)c4ccccc4Cl)sc23)c1)C(F)(F)F.O=S(=O)(Cl)c1ccc2c(c1)OCCCO2>>C[C@@](O)(c1ccnc(-c2cccc3cc([C@H](NS(=O)(=O)c4ccc5c(c4)OCCCO5)c4ccccc4Cl)sc23)c1)C(F)(F)F,CN(C)c1ccncc1,CN(C)C=O,CO,CCN(C(C)C)C(C)C,,test
US20110294793A1,CCN(CC)CC.ClCCl.Fc1ccc(CNCc2cccc(-c3ccc(Cl)cc3)c2)cc1.O=C(O)c1cc(Cl)c(O)c(S(=O)(=O)Cl)c1>>O=C(NCc1ccccc1)c1cc(Cl)c(O)c(S(=O)(=O)N(Cc2ccc(F)cc2)Cc2cccc(-c3ccc(Cl)cc3)c2)c1,,ClCCl,ClCCl,,,test
US20090076282A1,Cc1cc(Cl)c(N)cc1S.FC(F)(F)CI>>Cc1cc(Cl)c(N)cc1SCC(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030083315A1,CCOC(=O)CCCSc1nc2ccccc2[nH]1.Cc1cccc2cccc(CBr)c12>>CCOC(=O)CCCSc1nc2ccccc2n1Cc1cccc2cccc(C)c12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120065197A1,CCC1(C(=O)[O-])C=CC=C(C2=CCN(C(=O)OC(C)(C)C)CC2)N1>>CCOC(=O)c1cccc(C2CCN(C(=O)OC(C)(C)C)CC2)n1,[Pd],,,CCO,,test
US20020165241A1,CSc1ncc(C#N)c(Cl)n1>>CSc1ncc(C#N)cn1,[Zn],CCO,O,CC(=O)O,,test
US20150182503A1,CCC(C(=O)OC)(c1ccc(C(F)(F)F)cc1)n1ncc2c([N+](=O)[O-])cc(F)cc21>>CCC(C(=O)OC)(c1ccc(C(F)(F)F)cc1)n1ncc2c(N)cc(F)cc21,[Ni],CO,,,,test
US04650871,COc1ccccc1N1CCN(N)CC1.NS(=O)(=O)c1cc(C(=O)Cl)ccc1Cl>>COc1ccccc1N1CCN(NC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)CC1,,CCN(CC)CC,,,,test
US20150291563A1,CS(=O)(=O)Cl.OC(C1=NN(c2ccc(F)cc2F)C(c2ccc(N3CCNCC3)cc2)C1)(C(F)(F)F)C(F)(F)F>>CS(=O)(=O)N1CCN(c2ccc(C3CC(C(O)(C(F)(F)F)C(F)(F)F)=NN3c3ccc(F)cc3F)cc2)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20120071514A1,COC(=O)c1cc(Br)c(Cl)cc1O.N>>NC(=O)c1cc(Br)c(Cl)cc1O,,CO,,,,test
US04592866,O=C(O)[C@@H](O)[C@H](O)C(=O)O>>O=C(O)C[C@H](O)C(=O)O,,CO,,,,test
US05166198,CCOP(=O)(CCC(O)COn1cnc2c(N)ncnc21)OCC>>Nc1ncnc2c1ncn2OCC(O)CCP(=O)(O)O,,CN(C)C=O,,C[Si](C)(C)Br,,test
US20070173486A1,FC(F)(F)c1ccccc1[Mg]Br.O=Cc1ccc(Cl)cc1>>OC(c1ccc(Cl)cc1)c1ccccc1C(F)(F)F,,C1CCOC1,,,,test
US20130172249A1,CCCn1c(=O)[nH]c2nc(-c3cnn(Cc4cccc(C(F)(F)F)c4)c3)[nH]c2c1=O.O=P(Cl)(Cl)Cl>>CCCn1c(Cl)nc2nc(-c3cnn(Cc4cccc(C(F)(F)F)c4)c3)[nH]c2c1=O,,O=P(Cl)(Cl)Cl,,[Cl-].[NH4+],,test
US20130059834A1,CC(C)[Mg]Cl.CCCC[Sn](Cl)(CCC)CCCC.Cn1nc(I)c2cc(OC(F)F)ccc21>>CCCC[Sn](CCCC)(CCCC)c1nn(C)c2ccc(OC(F)F)cc12,,C1CCOC1,,,,test
US20110098425A1,CN(C)C=O.COc1ccccc1-c1ccccc1>>COc1c(C=O)cccc1-c1ccccc1,,C1CCOC1,,CN(C)CCN(C)C,[Li]CCCC,test
US20120071482A1,COC(C)(C)OC.OC[C@H]1C[C@@H](Nc2cc(Cl)ncn2)[C@H](O)[C@@H]1O>>CC1(C)O[C@H]2[C@H](Nc3cc(Cl)ncn3)C[C@H](CO)[C@H]2O1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20140364411A1,CC(C)(C#N)C(=O)CC#N.NNc1cccc(O)c1>>CC(C)(C#N)c1cc(N)n(-c2cccc(O)c2)n1,,CCO,,Cl,,test
US04112098,CC(=O)Nc1cc2c3ccccc3[nH]c(=O)n2n1>>Nc1cc2c3ccccc3[nH]c(=O)n2n1,,[K+],[OH-],,,test
US20140018319A1,COc1ccc(CN(c2nc(Nc3cc(C#N)cc(OC4CCNC4)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1.O=C1COC1>>N#Cc1cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c(Cl)c(OC2CCN(C3COC3)C2)c1,,CO,ClCCl,CC(=O)O,[BH3-]C#N.[Na+],test
US04663336,NCC(=O)O.O=C(Cl)CCc1ccccc1>>O=C(O)CNC(=O)CCc1ccccc1,,CCOCC,O,[Na+].[OH-],,test
US20120208839A1,Cc1ccc(CNC(=O)C(C)(C)C)c(C)c1[N+](=O)[O-]>>Cc1ccc(CNC(=O)C(C)(C)C)c(C)c1N,[Pd],CO,,,,test
US20120225862A1,CN(C)CC#Cc1ccc(S(=O)(=O)NCc2ccc(C(=O)Nc3cccnc3)cc2)cc1>>CN(C)CCCc1ccc(S(=O)(=O)NCc2ccc(C(=O)Nc3cccnc3)cc2)cc1,[Pd],CO,,,,test
US04694017,NC(Cc1c[nH]c2ccccc12)C(=O)O.O=C(Cl)c1ccc(Cl)cc1>>O=C(NC(Cc1c[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1,,CC(C)=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20070161776A1,CCCCCCCCC#Cc1sc2c(sc3c2sc2c4sccc4sc23)c1CCCCCCCCCC>>CCCCCCCCCCc1sc2c(sc3c2sc2c4sccc4sc23)c1CCCCCCCCCC,[Pt],CCOC(C)=O,,,,test
US20100331312A1,COc1cccc(C=O)c1Cl.C[N+](=O)[O-]>>COc1cccc(C=C[N+](=O)[O-])c1Cl,,CC(=O)O,,C,O=C[O-].[NH4+],test
US20150225342A1,COc1cccc(C2(O)CC3CN(C(=O)OCc4ccccc4)CC3C2)c1>>COc1cccc(C2(O)CC3CNCC3C2)c1,[Pd],CCO,,,,test
US20100197678A1,Cn1cc(C(=O)C(F)(F)F)c2ccccc21.Fc1ccc(-n2nnc3cc(Br)ccc32)cc1>>Cn1cc(C(O)(c2ccc3c(c2)nnn3-c2ccc(F)cc2)C(F)(F)F)c2ccccc21,,C1CCOC1,,[Li]CCCC,,test
US04125732,COC(=O)Cc1ccc(OC(C)COc2ccc(Cl)cc2)cc1.O=C1CCC(=O)N1Br>>COC(=O)C(Br)c1ccc(OC(C)COc2ccc(Cl)cc2)cc1,,ClC(Cl)(Cl)Cl,,,,test
US06235771B1,CCCBr.O=Cc1cc(Br)ccc1O>>CCCOc1ccc(Br)cc1C=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160251339A1,Clc1ccc2cc[nH]c2c1.O=N[O-]>>O=Cc1n[nH]c2cc(Cl)ccc12,,C1CCOC1,,O,,test
US20100075948A1,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2)C1(C#N)c1ccc(Cl)cc1.O=C(CN1CCNCC1)N1CCCC1>>CC(C)(C)CC1NC(C(=O)N2CCN(CC(=O)N3CCCC3)CC2)C(c2cccc(Cl)c2)C1(C#N)c1ccc(Cl)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04872901,COc1nc(C)nc(N[Si](C)(C)C)n1.S=C(Cl)Oc1ccccc1>>COc1nc(C)nc(N=C=S)n1,,Cc1ccccc1C,,,,test
US04652563,NCc1ccccc1.O=CC(O)CO>>OCC(O)CNCc1ccccc1,[Pd],CO,,,,test
US20130096118A1,Cc1ccc(CO)c(C(=O)O)c1>>Cc1ccc(C=O)c(C(=O)O)c1,O=[Mn]=O,C1CCOC1,,,,test
US20150045378A1,COc1cc(C(C2CC2)C2C(=O)OC(C)(C)OC2=O)ccc1F>>COc1cc(C(CC(=O)O)C2CC2)ccc1F,,CN(C)C=O,,O,,test
US20140323435A1,CN(C)CCN.Clc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3>>CN(C)CCNc1nc(-c2ccncc2)nc2sc3c(c12)CCCC3,,CC(=O)N(C)C,,CCN(CC)CC,,test
US20100113545A1,BrCc1ccc(Br)cc1.CO>>COCc1ccc(Br)cc1,,CO,,C[O-].[Na+],,test
US20090069337A1,CO[C@H]1CCNC1.O=[N+]([O-])c1ccc(Cl)nc1>>CO[C@H]1CCN(c2ccc([N+](=O)[O-])cn2)C1,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US20070072897A1,C1CCOC1.CCC(Br)(Br)CC.O=C1Cc2cc(Cl)ccc2N1>>O=C1Nc2ccc(Cl)cc2C12CCCCC2,,C1CCOC1,,[Cl-].[Li+],,test
US06403586B1,CCOC(=O)c1cc(-c2ccc(OC)cc2)nn(CC2CC2)c1=O.NCc1ccccn1>>COc1ccc(-c2cc(C(=O)NCc3ccccn3)c(=O)n(CC3CC3)n2)cc1,,Cc1ccccc1C,,,,test
US04515814,ClCC1CO1.Oc1ccc(CCOC2CCCCC2)cc1>>c1cc(OCC2CO2)ccc1CCOC1CCCCC1,,O,,[Na+].[OH-],,test
US20060189623A1,CC(C)(C)OC(=O)N1CCC(c2ccc(N)c(Br)c2)CC1.OB(O)C1=CCCCC1>>CC(C)(C)OC(=O)N1CCC(c2ccc(N)c(C3=CCCCC3)c2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,Cc1ccccc1,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20100239631A1,Clc1ccnc(Cl)n1.Sc1ccccc1>>Clc1nccc(Sc2ccccc2)n1,,CCO,CCOC(C)=O,[Na],,test
US20060235033A1,CC(N)c1nccs1.COc1cc2nccc(Oc3ccc(N)c(F)c3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)NC(C)c4nccs4)c(F)c3)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20120232051A1,CC1CCCCN1c1ccncc1N(C)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(O)C(F)(F)F>>CNc1cnccc1N1CCCCC1C.O=C(O)C(F)(F)F,,ClCCl,,,,test
US06380238B1,O=C(O)c1cc2ccc(Cl)c(F)c2[nH]1>>Fc1c(Cl)ccc2cc[nH]c12,,c1ccc(Oc2ccccc2)cc1,,,,test
US05102897,CC(C)(C)c1cc(SCCC(=O)NN)cc(C(C)(C)C)c1O.CCOC(C)=O.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)c1cc(S(=O)CCc2n[nH]c(=O)o2)cc(C(C)(C)C)c1O,,ClCCl,,,,test
US20100063058A1,CO.FC(F)(F)c1cc(Br)c(Br)nn1>>COc1cc(C(F)(F)F)nnc1Br,,CO,,CC(=O)O,C[O-].[Na+],test
US20140179676A1,Cn1nc(C#N)cc1[N+](=O)[O-].NO>>Cn1nc(C(N)=NO)cc1[N+](=O)[O-],,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20030092925A1,C=CCBr.CCOC(=O)CC(=O)c1ccccc1.[Na]>>C=CCCC(=O)c1ccccc1.[Na],,CCO,O,[K+].[OH-],,test
US20060205740A1,Clc1nccc(I)n1.Fc1cccc(COc2ccc(Nc3ncncc3I)cc2Cl)c1.Nc1ccccc1>>Fc1cccc(COc2ccc(Nc3ncncc3/C=C/c3cccnc3)cc2Cl)c1,,CC(C)O,,Cl,,test
US20050176789A1,CCC(C(=O)O)c1ccccc1.COc1ncccc1Cc1cnc(N)s1>>CCC(C(=O)Nc1ncc(Cc2cccnc2OC)s1)c1ccccc1,,CC#N,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06087390,CCCCCCOC1C2OC3(OCC45CC6C(C)CCC6C6(C=O)CC4C=C(C(C)C)C65C(=O)OC(c4ccccc4)c4ccccc4)OC2OC1C3O[Si](C)(C)C(C)(C)C>>CCCCCCOC1C2OC3(OCC45CC6C(C)CCC6C6(C=O)CC4C=C(C(C)C)C65C(=O)OC(c4ccccc4)c4ccccc4)OC2OC1C3O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20020019416A1,NC(=O)C[C@H](Cc1ccc2ccccc2c1)OC(=O)[C@H](CCCC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2n1Cc1ccccc1>>NC(=O)C[C@H](Cc1ccc2ccccc2c1)OC(=O)[C@H](CCCC(=O)O)NC(=O)c1cc2ccccc2n1Cc1ccccc1,[Pd],CO,O,[H][H],,test
US20060079547A1,COC(=O)c1ccsc1N.COC(C)(C)OC>>COC(=O)c1ccsc1NC(C)C,O=C(O)C(F)(F)F,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090062360A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H](N)c1ccc(O)cc1>>COC(=O)C(NC(=O)OC(C)(C)C)c1ccc(O)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US04670604,COC(=O)C(=O)Nc1cccc(OC)c1>>COC(=O)C(=O)Nc1cccc(O)c1,,ClCCl,,BrB(Br)Br,O,test
US20080027096A1,BrCc1cccc(Br)c1.COC(=O)C(Cl)Cc1cc(Br)c(O)c(Br)c1>>O=C(O)C(Cl)Cc1cc(Br)c(OCc2cccc(Br)c2)c(Br)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05393779,NC(=O)Cc1ccc(OCCNCc2ccccc2)cc1.c1ccc([C@@H]2CO2)cc1>>NC(=O)Cc1ccc(OCCN(Cc2ccccc2)C[C@H](O)c2ccccc2)cc1,,CC(C)O,,,,test
US20070232601A1,COC(=O)CCC(=O)CNC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COC(=O)CCc1cnc([C@@H]2CCCN2C(=O)OC(C)(C)C)s1,,Cc1ccccc1,,O,,test
US20100075965A1,CC=O.O=C(CCC1CCCCN1)Nc1cn2nc(Cl)ccc2n1>>CCN1CCCCC1CCC(=O)Nc1cn2nc(Cl)ccc2n1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20150291563A1,NNc1ccc(F)cc1F.O=C(C=Cc1ccc(F)c(Br)c1)C(F)(F)C(F)(F)F>>Fc1ccc(N2N=C(C(F)(F)C(F)(F)F)CC2c2ccc(F)c(Br)c2)c(F)c1,,CC(=O)O,,Cl,,test
US20160159773A1,Cn1nc(N2C(=O)c3ccccc3C2=O)cc1C(C)(C)CO>>Cn1nc(N)cc1C(C)(C)CO,,CCO,,NN,O,test
US20070161648A1,COc1ccc2c(c1)cc(-c1ccc([N+](=O)[O-])c3c1C(=O)NC3)n2C(=O)OC(C)(C)C>>COc1ccc2[nH]c(-c3ccc([N+](=O)[O-])c4c3C(=O)NC4)cc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130116243A1,BrCC1CCC1.CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)NC(=O)CO4)cc2)CCC1>>NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)N(CC3CCC3)C(=O)CO4)cc2)CCC1,,CN(C)C=O,,[H-].[Na+],,test
US20020173507A1,C=O.O=C(Nc1cccc(OCCC2CCNCC2)n1)Nc1csc(-c2ccncc2)n1>>CN1CCC(CCOc2cccc(NC(=O)Nc3csc(-c4ccncc4)n3)n2)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070213339A1,CCOC=C(C(=O)OCC)C(=O)c1cc(F)c(F)c(Cl)c1F.CN(C)CCc1ccc(N)cc1>>CN(C)CCc1ccc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Cl)c32)cc1,,CCO,CCO,Cl,O,test
US05202344,CCOC(=O)C1=C(O)C(=O)N(c2ccccc2)C1.NO>>CCOC(=O)C1CN(c2ccccc2)C(=O)C1=NO,,c1ccncc1,,Cl,,test
US20100286088A1,COc1ccc(CN=C=O)c(OC)c1.[N-]=[N+]=C1N=CN=C1C(N)=O>>COc1ccc(Cn2nnc3c(C(N)=O)ncn3c2=O)c(OC)c1,,CS(C)=O,,,,test
US04780477,CC(C)N(CCN1C(=O)/C(=N/NC(N)=O)c2ccccc21)C(C)C.Cl>>CC(C)N(CCN1C(=O)/C(=N/NC(N)=O)c2ccccc21)C(C)C.Cl,,CO,,,,test
US20100056511A1,CCOC(=N)Cc1ccc([N+](=O)[O-])cc1.COC(CN)OC>>O=[N+]([O-])c1ccc(Cc2ncc[nH]2)cc1,,CCO,,Cl,,test
US20060019943A1,Br[Mg]c1ccccc1.CCOC1=CC(=O)CCC1>>O=C1C=C(c2ccccc2)CCC1,,C1CCOC1,,Cl,,test
US20090221655A1,COC(=O)[C@H](O)CNc1ccc2c(C)noc2c1.O=C(n1ccnc1)n1ccnc1>>COC(=O)[C@H]1CN(c2ccc3c(C)noc3c2)C(=O)O1,,ClCCl,,CC#N,O,test
US20070066820A1,Cc1ccc(S(=O)(=O)OC[C@H]2CCCN2C(=O)OC(C)(C)C)cc1.Oc1ccc(I)cc1>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc(I)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20080125436A1,CI.Cn1c(S)nnc1-c1ccn(COCC[Si](C)(C)C)c(=O)c1>>CSc1nnc(-c2ccn(COCC[Si](C)(C)C)c(=O)c2)n1C,,O,,CCO,[Na+].[OH-],test
US20130261125A1,COC(=O)C1(Cc2ccc(F)cc2)CCCC(N)C1.Cc1cc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3ccc(C(=O)O)cc23)ccn1>>COC(=O)C1(Cc2ccc(F)cc2)CCCC(NC(=O)c2ccc3c(c2)c(-c2ccnc(C)c2)nn3C(c2ccccc2)(c2ccccc2)c2ccccc2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04128562,CCOC(=O)CC(=S)SCC.N#CCCl>>CCSc1cc(O)c(C#N)s1,,CO,,C[O-].[Na+],,test
US20110098480A1,COC(=O)CCc1ccc(C(=O)CCc2sc3cc(C(F)(F)F)ccc3c2C(C)C)cc1C.NO>>COC(=O)CCc1ccc(C(CCc2sc3cc(C(F)(F)F)ccc3c2C(C)C)=NO)cc1C,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US04913837,CCCCCc1ccc(-c2cnc(O)cn2)cc1.CCCc1ccc(C(=O)O)cc1>>CCCCCc1ccc(-c2cnc(OC(=O)c3ccc(CCC)cc3)cn2)cc1,,c1ccncc1,,O=S(Cl)Cl,,test
US20160009683A1,CCOC(=O)C(F)(F)c1ccc(SC#N)cn1.C[Si](C)(C)C(F)(F)F>>CCOC(=O)C(F)(F)c1ccc(SC(F)(F)F)cn1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04808624,CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1O.COC(=O)CBr>>CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(=O)OC,,CN(C)C=O,,Cl,[H-].[Na+],test
US20130172384A1,O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(Br)cc3)n[nH]c2=O)C1.OB(O)c1ccc2cc[nH]c2c1>>O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(-c4ccc5cc[nH]c5c4)cc3)n[nH]c2=O)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US06593489B1,CC(C)(C)OC(=O)N1C(=O)C2C=CC1C2.CO>>COC(=O)C1=CC[C@H](NC(=O)OC(C)(C)C)C1,,CO,,C[O-].[Na+],,test
US05578627,CN(C)c1ccc2onc(OCC(CO)NC(=O)OC(C)(C)C)c2c1.O=C=NC(=O)C(Cl)(Cl)Cl>>CN(C)c1ccc2onc(OCC(COC(N)=O)NC(=O)OC(C)(C)C)c2c1,,ClCCl,,O,,test
US20110003793A1,CI.O=C1CCCc2c1[nH]c1cc(Br)ccc21>>Cn1c2c(c3ccc(Br)cc31)CCCC2=O,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05047411,CCN=C=O.Cc1ccn2c(Cc3ccc(O)c(N)c3)c(C)nc2c1>>CCNC(=O)Nc1cc(Cc2c(C)nc3cc(C)ccn23)ccc1O,,C1CCOC1,CCO,,,test
US05686469,CC(C)C[C@H](N)CN1CCC[C@H]1C(=O)NCCCCc1ccccc1.O=C(Cl)C12CC3CC(CC(C3)C1)C2>>CC(C)C[C@@H](CN1CCC[C@H]1C(=O)NCCCCc1ccccc1)NC(=O)C12CC3CC(CC(C3)C1)C2,,ClCCl,,CCN(CC)CC,,test
US20030087926A1,C=Cc1ccccc1Cl.CCC(=O)C(=O)[O-].Nc1ccc(Cl)cc1>>CCOC(=O)C1CC(c2ccccc2Cl)c2cc(Cl)ccc2N1,,CC#N,,O=C(O)C(F)(F)F,,test
US20020038858A1,CCC[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](CCC=COC)CC2)CC1>>CCC[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](CCCC=O)CC2)CC1,,Cc1ccccc1,,O=CO,,test
US03941823,CCCCCCCCCCCCCCCCCCO.COC(=O)CC#N.Cl>>CCCCCCCCCCCCCCCCCCOC(=N)CC(=O)OC.Cl,,CCOCC,,,,test
US20100160327A1,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(C(C(=O)Nc2ccccc2)C(=O)Nc2ccccc2)cc1.CI>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(C(C)(C(=O)Nc2ccccc2)C(=O)Nc2ccccc2)cc1,,C1CCOC1,CCOC(C)=O,CC(C)(C)[O-].[K+],,test
US05710275,CC(C)=O.COC(=O)CC(C)=O.C[Si](C)(C)N(C(=O)C(F)(F)F)[Si](C)(C)C.Cc1ccccc1.ClCCl.N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O>>C[C@H]1C=C2N(C)C(=O)CC[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@H]3O)[C@H]12,,CC(C)=O,ClCCl,O=S(=O)(O)C(F)(F)F,,test
US04997840,COc1ccc(N(C)C(C)=O)cc1C>>CNc1ccc(OC)c(C)c1,,O,,[Na+].[OH-],,test
US20050272036A1,CC(=O)c1ccc(C(F)(F)F)cc1.O=Cc1ccc(F)cc1>>O=C(C=Cc1ccc(F)cc1)c1ccc(C(F)(F)F)cc1,,CCO,O,[Na+].[OH-],,test
US20080076800A1,COc1cccc(-c2ccc(C#N)c(NC3CCC(O)CC3)c2)c1OC.OO>>COc1cccc(-c2ccc(C(N)=O)c(NC3CCC(O)CC3)c2)c1OC,,CS(C)=O,,CCO,[Na+].[OH-],test
US20160176864A1,CC#N.COC(=O)c1ccc2c3ncc(-c4c(C)noc4C)cc3n([C@H](c3ccccc3)C3CCOCC3)c2c1>>Cc1noc(C)c1-c1cnc2c3ccc(C(=O)CC#N)cc3n([C@H](c3ccccc3)C3CCOCC3)c2c1,,C1CCOC1,,[Li]CCCC,,test
US04734429,CI.Cn1ncc2c1CCCc1[nH]ncc1-2>>Cn1ncc2c1CCCc1c-2cnn1C,,CN(C)C=O,,[H-].[Na+],,test
US20150336991A1,CCOC(=O)CCC(O[Si](C)(C)C)c1cc([N+](=O)[O-])ccc1Cl>>O=C1CCC(c2cc([N+](=O)[O-])ccc2Cl)O1,,ClCCl,,O,O=C(O)C(F)(F)F,test
US04188485,O=C1CCN(CC2c3ccccc3CCc3ccccc32)CC1.[Li]C(C)(C)C>>CC(C)(C)C1(O)CCN(CC2c3ccccc3CCc3ccccc32)CC1,,c1ccccc1,,,,test
US20130150341A1,Br.BrBr.O=C1CCNCC1>>Br.O=C1CCNCC1Br,,CC(=O)O,,,,test
US20140323474A1,CNN.COC(OC)C(C(OC)OC)[C@H]1C[C@H]2CSC(NC(=O)c3ccccc3)=N[C@@]2(c2cc(Br)ccc2F)CO1>>Cn1cc([C@H]2C[C@H]3CSC(N)=N[C@@]3(c3cc(Br)ccc3F)CO2)cn1,,CCO,,O,O=S(=O)(O)O,test
US07094798B1,O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c2cc(O)ccc2n1CCCBr.[Li]SC>>CSCCCn1c2ccc(O)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O,,C1COCCO1,O,[Li],,test
US05712267,C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(S[C@H]3C[C@@H](C(=O)N4CC[C@@H](NC(=O)OCc5ccc([N+](=O)[O-])cc5)C4)N(C(=O)OCc4ccc([N+](=O)[O-])cc4)C3)[C@H](C)[C@H]12.Cl>>C[C@@H](O)[C@H]1C(=O)N2C(C(=O)O)=C(S[C@@H]3CN[C@H](C(=O)N4CC[C@@H](N)C4)C3)[C@H](C)[C@H]12.Cl,,C1CCOC1,O,,,test
US20130150357A1,C[C@@H]1NC(C)(C)COC1=O.Cc1ccc([Mg]Br)cc1>>Cc1ccc([C@]2(O)OCC(C)(C)N[C@H]2C)cc1,,C1CCOC1,,CCOCC,[Cl-].[NH4+],test
US20140371212A1,C=CCO.CON(C)C(=O)CBr>>C=CCOCC(=O)N(C)OC,,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20150175594A1,Cc1nsc(-c2c(N)sc3c2CCC(F)(F)C3)n1.O=C1OC(=O)C2=C1CCC2>>Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCC3)sc3c2CCC(F)(F)C3)n1,,CO,ClCCl,,,test
US05998433,COc1cc(CC(=O)N2CCc3cc(CN(C)C)oc3C2)ccc1OCc1ccccc1.Cl>>COc1cc(CC(=O)N2CCc3cc(CN(C)C)oc3C2)ccc1OCc1ccccc1.Cl,,CCOC(C)=O,CO,,,test
US20120232074A1,COc1cc2c(Cl)c(C(N)=O)cnc2cc1-c1c(C)noc1C.Cc1ccc(CN)o1>>COc1cc2c(NCc3ccc(C)o3)c(C(N)=O)cnc2cc1-c1c(C)noc1C,,C1COCCO1,,,,test
US20100113458A1,CS(=O)(=O)Cl.O=[N+]([O-])c1ccc2cc[nH]c2c1>>CS(=O)(=O)n1ccc2ccc([N+](=O)[O-])cc21,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20120245345A1,COc1ccc2ncc3c(c2n1)OC([C@@H]1CC[C@@H](N)CC1)C(=O)N3.CSC>>COc1ccc2ncc3c(c2n1)OC([C@@H]1CC[C@@H](N)CC1)CN3C,,C1CCOC1,,B,,test
US20040192701A1,Nc1ccc2[nH]ccc2c1.O=C(O)CN(CC(=O)O)Cc1ccccc1>>O=C1CN(Cc2ccccc2)CC(=O)N1c1ccc2[nH]ccc2c1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20070027185A1,Nc1ccc(Cl)cn1.Nc1ncccc1C(=O)O.O=C(Cl)C(=O)Cl>>Cl.Nc1ncccc1C(=O)Nc1ccc(Cl)cn1,CN(C)C=O,ClCCl,,c1ccncc1,,test
US04743616,COC(=O)[C@@H]1CCCN1.O=C(Cl)Cc1ccccc1>>COC(=O)[C@@H]1CCCN1C(=O)Cc1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
US20120258957A1,COc1cc2c(cc1OC)C(CO)N(C(=O)[C@@H]1Cc3ccccc3CN1C(=O)OC(C)(C)C)CC2>>COc1cc2c(cc1OC)C(CO)N(C(=O)[C@@H]1Cc3ccccc3CN1)CC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150025065A1,Brc1ccc(I)cc1.CC(C)(C)OC(=O)NCC1CCNCC1>>CC(C)(C)OC(=O)NCC1CCN(c2ccc(Br)cc2)CC1,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020173664A1,CC(=O)N1C(=O)OC(=O)[C@@H]1C.Cc1ccc([C@H](C)N)cc1>>CC(=O)N[C@@H](C)C(=O)N[C@@H](C)c1ccc(C)cc1,,CCOC(C)=O,,Cl,,test
US20070112019A1,O=C1CCC(=O)N1Cl.Oc1cccc(Cl)c1F>>Oc1ccc(Cl)c(Cl)c1F,,CC#N,,O=C(O)C(F)(F)F,,test
US20150025070A1,CCOC(=O)CN1CCC(c2nnc(-c3ccccc3)o2)CC1>>O=C(O)CN1CCC(c2nnc(-c3ccccc3)o2)CC1,,CCO,O,Cl,[Na+].[OH-],test
US20110028509A1,NCC1CC1.O=C(O)c1ccc(CBr)cc1>>O=C(NCC1CC1)c1ccc(CBr)cc1,,C1CCOC1,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US20160184254A1,CC(C)(C)OC(=O)NCC(=O)O.CC(C)=CCC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/Cc1c(C)c(O)c2ccccc2c1OC(=O)c1ccccc1>>CC(C)=CCC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/Cc1c(C)c(OC(=O)CNC(=O)OC(C)(C)C)c2ccccc2c1OC(=O)c1ccccc1,CN(C)c1ccncc1,CCOCC,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20120040984A1,CC(C)(C)OC(=O)C[C@@H]1CC[C@@H](c2ccc(C(=O)Nc3nnc(CS(=O)Cc4ccccc4)s3)cc2)CC1>>O=C(O)C[C@@H]1CC[C@@H](c2ccc(C(=O)Nc3nnc(CS(=O)Cc4ccccc4)s3)cc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070281933A1,C1CCN(C2CCNCC2)CC1.NC(=O)c1cc(-c2cccc(F)c2)cc2c(C3CCN(S(=O)(=O)CCCCl)CC3)n[nH]c12>>NC(=O)c1cc(-c2cccc(F)c2)cc2c(C3CCN(S(=O)(=O)CCCN4CCC(N5CCCCC5)CC4)CC3)n[nH]c12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110046093A1,CN1C(=O)C2(CC2)CN(C2CCCC2)c2nc(Nc3ccc(C(=O)O)cc3F)ncc21.CN1CCN(N)CC1>>CN1CCN(NC(=O)c2ccc(Nc3ncc4c(n3)N(C3CCCC3)CC3(CC3)C(=O)N4C)c(F)c2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US04167574,CCC(=O)N(c1ccccc1)C1(COC)CCN(CC(O)c2ccccc2)CC1.Cl.O=S(Cl)Cl>>CCC(=O)N(c1ccccc1)C1(COC)CCN(CC(Cl)c2ccccc2)CC1.Cl,,ClCCl,,,,test
US20150105404A1,Clc1nc2ccc(Br)cc2cc1-c1ccccc1.Cn1cncc1C(=O)c1ccc(Cl)cc1>>Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(Cl)c(-c3ccccc3)cc2c1,,C1CCOC1,,[Li]CCCC,,test
US05677306,O=C1CCc2c(Cl)cc(Cl)cc21.O=C1c2cccc(F)c2CC1Br>>O=C1c2cc(Cl)cc(Cl)c2CC1Br,Br[Cu]Br,C1COCCO1,,,,test
US20120077828A1,COc1ccccc1CC(=O)O.Nc1nccc2scc(-c3ccc4c(c3)CCN4)c12>>COc1ccccc1CC(=O)N1CCc2cc(-c3csc4ccnc(N)c34)ccc21,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150152112A1,CO.O=C(O)CCCC(=O)Nc1ccc(-c2cnc([C@@H]3CCc4cc(-c5cc(Cl)ccc5-n5cnnn5)cc(=O)n43)[nH]2)cc1>>COC(=O)CCCC(=O)Nc1ccc(-c2cnc([C@@H]3CCc4cc(-c5cc(Cl)ccc5-n5cnnn5)cc(=O)n43)[nH]2)cc1,,CO,,O=CO,,test
US20070105819A1,CCOC(=O)c1ccc(Sc2ccccc2C(=O)OC)c([N+](=O)[O-])c1>>O=C(O)c1ccc(Sc2ccccc2C(=O)O)c([N+](=O)[O-])c1,,C1CCOC1,,[Li+].[OH-],,test
US20100292215A1,CCOC(=O)c1ccc(O)cc1.O=C1c2ccccc2C(=O)N1C1CCC(O)CC1>>CCOC(=O)c1ccc(OC2CCC(N3C(=O)c4ccccc4C3=O)CC2)cc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060287300A1,CC(C)CCC1(OCC(=O)O)C(=O)CC(=O)c2ccccc21.CO>>COC(=O)COC1(CCC(C)C)C(=O)CC(=O)c2ccccc21,,C1CCOC1,CO,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20100105921A1,O=Cc1ccc(Br)cc1.O=Nc1ccccc1>>O=C(c1ccc(Br)cc1)N(O)c1ccccc1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20060293385A1,CCC(CC)(c1ccc(NS(=O)(=O)CCCl)c(C)c1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1.CCS>>CCSCCS(=O)(=O)Nc1ccc(C(CC)(CC)c2ccc(OCC(=O)C(C)(C)C)c(C)c2)cc1C,,C1CCOC1,,[H-].[Na+],,test
US07074801B1,Nc1ccc(F)cc1.O=C(O)C1CCN(c2ccnc3ccc(Br)cc23)CC1>>O=C(Nc1ccc(F)cc1)C1CCN(c2ccnc3ccc(Br)cc23)CC1,,C1CCOC1,O,CC(C)COC(=O)Cl,CCN(CC)CC,test
US20070249642A1,Clc1ccc(C23CNCC2C3)cc1.O=CCCn1cc(I)c(=O)n(C(=O)c2ccccc2)c1=O>>O=C(c1ccccc1)n1c(=O)c(I)cn(CCCN2CC3CC3(c3ccc(Cl)cc3)C2)c1=O,,ClCCCl,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20060217387A1,C#Cc1cnn2c(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)nc12.O=S(=O)(Nc1ccncc1)c1ccc(Br)s1>>O=S(=O)(Nc1ccncc1)c1ccc(C#Cc2cnn3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)s1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060194849A1,COc1cc(C)ccn1.O=C1CCC(=O)N1Cl>>COc1cc(C)c(Cl)cn1,,O,,CN(C)C=O,,test
US20050065189A1,CCOC(=O)c1nc(-c2ccc(Cl)cc2Cl)c(-c2ccccc2)s1>>O=C(O)c1nc(-c2ccc(Cl)cc2Cl)c(-c2ccccc2)s1,,CO,O,Cl,[K+].[OH-],test
US20150259295A1,CCOC(=O)Cc1ccc(Br)cc1.OB(O)c1ccc(O)cc1>>CCOC(=O)Cc1ccc(-c2ccc(O)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030065179A1,CN(C)S(=O)(=O)c1ccc2c(c1)CN(C(=O)C(F)(F)F)CC2>>CN(C)S(=O)(=O)c1ccc2c(c1)CNCC2,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20080255197A1,C[Si](C)(C)N=C=O.Cc1cnc(CN(C2CCNCC2)C(C)c2ccccn2)c(C)c1>>Cc1cnc(CN(C2CCN(C(N)=O)CC2)C(C)c2ccccn2)c(C)c1,,CC(C)O,,,,test
US20150376172A1,Cc1ccc([C@]2(C)C[C@@H](C(F)(F)F)ON2)c(F)c1>>Cc1ccc([C@@](C)(N)C[C@H](O)C(F)(F)F)c(F)c1,[Pd],CCO,,,,test
US20020137928A1,CN1CCC(=O)c2cn(CCCCCl)cc2S1(=O)=O.COc1ccccc1N1CCNCC1>>COc1ccccc1N1CCN(CCCCn2cc3c(c2)S(=O)(=O)N(C)CCC3=O)CC1,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US20070073060A1,COC(=O)c1cc2c3c(c[nH]c3c1)C=CS(=O)(=O)N2C>>COC(=O)c1cc2c3c(c[nH]c3c1)CCS(=O)(=O)N2C,[Pd],CO,,O=C[O-].[NH4+],,test
US20100305093A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCCc1cccc(F)c1F>>Cc1ccc(S(=O)(=O)OCCc2cccc(F)c2F)cc1,,ClCCl,,CCN(CC)CC,,test
US20070276000A1,COCOc1c(Br)c(C)cc2cc(OC)ccc12.OB(O)c1ccc(F)cc1>>COCOc1c(-c2ccc(F)cc2)c(C)cc2cc(OC)ccc12,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US04405552,N#Cc1ccc(-c2ccc(Cl)cc2)nc1.OO>>NC(=O)c1ccc(-c2ccc(Cl)cc2)nc1,,CC(C)=O,,CCO,[Na+].[OH-],test
US08778939B2,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.O=C(Nc1cccnc1)c1cc(Br)ccc1OCc1ccc(F)cc1F>>Cn1cc(-c2ccc(OCc3ccc(F)cc3F)c(C(=O)Nc3cccnc3)c2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US04678793,CC(=O)Cl.CN1C(=O)CC(C)(C)c2ccccc21>>CC(=O)c1ccc2c(c1)C(C)(C)CC(=O)N2C,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US04038396,Nc1ccccc1-c1nc2cccnc2o1.O=C(Cl)c1ccccc1>>O=C(Nc1ccccc1-c1nc2cccnc2o1)c1ccccc1,,c1ccncc1,,,,test
US20110256175A1,CCCCC/C=C\C/C=C\CCCCCCCCC(O)CCCCCCCC/C=C\C/C=C\CCCCC.O=C(Cl)CCBr>>CCCCC/C=C\C/C=C\CCCCCCCCC(CCCCCCCC/C=C\C/C=C\CCCCC)OC(=O)CCBr,,ClCCl,ClCCl,CCN(CC)CC,,test
US05968938,CCc1cccc(N2CCNCC2)c1.O=C(O)Cc1ccccc1OCC(F)(F)F>>CCc1cccc(N2CCN(C(=O)Cc3ccccc3OCC(F)(F)F)CC2)c1,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20120115868A1,COC(=O)c1cc(O)nn1C.Cc1nnn(-c2ccc(F)cc2)c1CO>>COC(=O)c1cc(OCc2c(C)nnn2-c2ccc(F)cc2)nn1C,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130261107A1,CCOC(=O)N1CCc2nc(CO)oc2C1.Oc1ccccc1>>CCOC(=O)N1CCc2nc(COc3ccccc3)oc2C1,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080269208A1,CC(C)(C)[Si](C)(C)Cl.OC[C@@H]1NCCN2CCC[C@@H]12>>CC(C)(C)[Si](C)(C)OC[C@@H]1NCCN2CCC[C@@H]12,,ClCCl,O,CCN(CC)CC,,test
US20100016330A1,C[C@H]1CN(C(=O)OC(C)(C)C)CCN1S(=O)(=O)c1ccc(C(F)(F)F)cc1.Cl>>C[C@H]1CNCCN1S(=O)(=O)c1ccc(C(F)(F)F)cc1.Cl,,C1COCCO1,,,,test
US20140371201A1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cc(Br)cnc1Cl>>CCOC(=O)/C=C/c1cc(Br)cnc1Cl,,C1CCOC1,,,,test
US20140171408A1,COC(=O)Cl.Nc1ncc(F)c2nc(-c3c(Cl)cccc3Cl)sc12>>COC(=O)Nc1ncc(F)c2nc(-c3c(Cl)cccc3Cl)sc12,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20130023541A1,CC(C)(C)CC(=O)Cl.CCN(Cc1ccc(CN2CCN(c3ncccc3CO)CC2)cc1)Cc1c(F)cccc1Cl>>CCN(Cc1ccc(CN2CCN(c3ncccc3COC(=O)CC(C)(C)C)CC2)cc1)Cc1c(F)cccc1Cl,,ClCCl,,CCN(CC)CC,CO,test
US20100130492A1,CS(=O)(=O)Cl.Cc1nc(N)ncc1-c1nc(N2CCOCC2)c2nc(Cl)n(CC3CC3)c2n1.NC1CCNC1>>Cc1nc(N)ncc1-c1nc(N2CCOCC2)c2nc(N3CCC(NS(C)(=O)=O)C3)n(CC3CC3)c2n1,,CN1CCCC1=O,,CCN(CC)CC,,test
US20090042929A1,CC1(C(=O)O)CC1.NCCc1cccs1>>CC1(C(=O)NCCc2cccs2)CC1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US20140155407A1,CCC(O)c1ccc(-c2ccccc2)nc1.O=C(n1ccnc1)n1ccnc1>>CCC(c1ccc(-c2ccccc2)nc1)n1ccnc1,,CN1CCCC1=O,,,,test
US06369070B1,CCOC(=O)c1cccc(N)c1.Cc1onc(-c2c(F)cccc2Cl)c1C(=O)Cl>>CCOC(=O)c1cccc(NC(=O)c2c(-c3c(F)cccc3Cl)noc2C)c1,,ClCCl,,CCN(CC)CC,,test
US20150018343A1,CCOC(=O)c1ccc(F)cc1OCC>>CCOc1cc(F)ccc1C(=O)O,,CCO,,[Na+].[OH-],,test
US20100183551A1,COC(=O)[C@@H]1C[C@H](OS(=O)(=O)c2ccc(Br)cc2)CN1C(=O)OC(C)(C)C.COc1cc2c(cc1Br)c(=O)[nH]c1cc(C#N)ccc12>>COC(=O)[C@@H]1C[C@@H](Oc2nc3cc(C#N)ccc3c3cc(OC)c(Br)cc23)CN1C(=O)OC(C)(C)C,,CCOC(C)=O,CN1CCCC1=O,O,O=C([O-])[O-].[Cs+].[Cs+],test
US05047540,CCCCCCCCCCCCCCCCCCNC(=O)OCC(CBr)COC(=O)c1ccccc1.CCCCCCCCCCCCCCCCOCC(CC#N)COC(=O)c1ccccc1>>CCCCCCCCCCCCCCCCCCNC(=O)OCC(CC#N)COC(=O)c1ccccc1,,CS(C)=O,,[C-]#N.[Na+],,test
US20150011527A1,CCCCCCCOc1ccc(-c2cnc(-c3ccc(C=C(NC(=O)OC(C)(C)C)C(=O)OC)cc3)s2)cc1>>CCCCCCCOc1ccc(-c2cnc(-c3ccc(CC(NC(=O)OC(C)(C)C)C(=O)OC)cc3)s2)cc1,[Pd],C1COCCO1,,[H][H],,test
US20090312338A1,CI.Cc1ccc(S(=O)(=O)n2ccc3c2ncc2nnc(C45CCC(NS(=O)(=O)C6CC6)(CC4)CC5)n23)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c2ncc2nnc(C45CCC(N(C)S(=O)(=O)C6CC6)(CC4)CC5)n23)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20050026914A1,CN1CCN(C(=O)Cc2ccc(N)cc2)CC1>>CN1CCN(CCc2ccc(N)cc2)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120295923A1,COC(=O)C=C1CC[C@@H](N)[C@H](c2ccc(C(F)(F)F)nc2)C1>>COC(=O)CC1CC[C@@H](N)[C@H](c2ccc(C(F)(F)F)nc2)C1,[Rh],CO,,[H][H],,test
US20090181942A1,CCN(CC)CC.CCN=C=NCCCN(C)C.CCOC(C)=O.COc1cccc([C@H]2O[C@H](CCC(=O)O)c3cccn3-c3ccc(Cl)cc32)c1OC.On1nnc2ccccc21>>CCOC(=O)C(=O)N1CCN(C(=O)CC[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3cccc32)CC1,,ClCCl,,Cl,,test
US20080306091A1,CCn1cc(C2(c3cccc(-c4cccnc4F)c3)N=C(N)N(C)C2=O)cc1C=O.CON.Cl>>CCn1cc(C2(c3cccc(-c4cccnc4F)c3)N=C(N)N(C)C2=O)cc1C=NOC.Cl,,C1CCOC1,,,,test
US20110281870A1,CC(C)C[C@@H](C(=O)N[C@H]1CC[C@@H]2CN(c3ccccc3C(F)(F)F)C[C@H]12)N(C)C(=O)OC(C)(C)C>>CN[C@@H](CC(C)C)C(=O)N[C@H]1CC[C@@H]2CN(c3ccccc3C(F)(F)F)C[C@H]12,,Cl,,C1COCCO1,,test
US20060122394A1,C[C@@H]1CCCN1c1nc(-c2ccc(F)cc2)cc(N2CCN(C(=O)OC(C)(C)C)C[C@H]2C)n1>>C[C@@H]1CCCN1c1nc(-c2ccc(F)cc2)cc(N2CCNC[C@H]2C)n1,,C1COCCO1,Cl,,,test
US20040122002A1,Clc1ccc(-c2cn3c(c2-c2ccccc2)CCC3)cc1.O=C(Cl)OC(Cl)(Cl)Cl.OCc1ccccc1>>O=C(OCc1ccccc1)c1c(-c2ccc(Cl)cc2)c(-c2ccccc2)c2n1CCC2,,C1CCOC1,,CCN(CC)CC,,test
US20040063768A1,CNC.N#Cc1ccc2[nH]cc(CC3CCCC3=O)c2c1>>CN(C)C1CCCC1Cc1c[nH]c2ccc(C#N)cc12,,CCO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20150299189A1,COC(=O)c1cc(C2CC2)cnc1Nc1ccc2c(c1)cc(C(=O)OC(C)(C)C)n2CC(C)C>>COC(=O)c1cc(C2CC2)cnc1Nc1ccc2c(c1)cc(C(=O)O)n2CC(C)C,,O=C(O)C(F)(F)F,,,,test
US20100210704A1,Cc1cc(F)c(-n2nc(OC(F)(F)C(F)C(F)(F)F)cc2Cl)cc1SCC(F)(F)F.O=C(OO)c1cccc(Cl)c1>>Cc1cc(F)c(-n2nc(OC(F)(F)C(F)C(F)(F)F)cc2Cl)cc1S(=O)CC(F)(F)F,,ClC(Cl)Cl,,,,test
US20070060607A1,CCOC(=O)c1cnc(N)c2c(COc3cc(NC(=O)c4ccc(Cl)cc4)ccc3C)csc12.NCCO>>Cc1ccc(NC(=O)c2ccc(Cl)cc2)cc1OCc1csc2c(C(=O)NCCO)cnc(N)c12,,CS(C)=O,,,,test
US20080161366A1,Cc1cccc(Nc2ccccc2[N+](=O)[O-])c1>>Cc1cccc(Nc2ccccc2N)c1,[Pd],CCOC(C)=O,,,,test
US04762844,Cc1cc([N+](=O)[O-])c(C(=O)O)cc1F>>Cc1cc(N)c(C(=O)O)cc1F,[Pd],C1COCCO1,,,,test
US06514989B1,CCOC(=O)NC(=S)Nc1ncccc1OC.NO>>COc1cccn2nc(N)nc12,,CCO,CO,CCN(C(C)C)C(C)C,Cl,test
US20100317865A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)[C@@](C)(CCCO[Si](C)(C)C(C)(C)C)C(=O)OC1CCCC1>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)[C@@](C)(CCCO)C(=O)OC1CCCC1,,CC(=O)O,CCOC(C)=O,C1CCOC1,O,test
US07935726B1,C(=NC1CCCCC1)=NC1CCCCC1.CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)O.Nc1ccc([N+](=O)[O-])cc1>>N[C@@H](CC(=O)OCc1ccccc1)C(=O)Nc1ccc([N+](=O)[O-])cc1.Nc1ccc([N+](=O)[O-])cc1,,ClCCl,,,,test
US05616620,COc1ccc(CNC(=O)[C@H](CCCNC(N)=N[N+](=O)[O-])NC(=O)C(c2ccccc2)c2ccccc2)cc1OC>>COc1ccc(CNC(=O)[C@H](CCCNC(=N)N)NC(=O)C(c2ccccc2)c2ccccc2)cc1OC,[Pd],CC(=O)O,,,,test
US20110082133A1,Cc1cccc(N(C)Cc2c(Cl)cc(Cl)c(=O)n2CCc2ccc(C(=O)OC(C)(C)C)cc2)c1>>Cc1cccc(N(C)Cc2c(Cl)cc(Cl)c(=O)n2CCc2ccc(C(=O)O)cc2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05750520,CC(Cl)OC(=O)Cl.CN(C)c1cccc2cccc(N(C)C)c12.Cc1ccccc1>>CCOC(=O)[C@H]1CC(C)=CCN1.Cl,,Cc1ccccc1,,CCO,,test
US04783461,COc1ccc(C(=O)Cl)cc1.N#CCc1nnc(NN)c2ccccc12>>COc1ccc(-c2nnc3c4ccccc4c(CC#N)nn23)cc1,,C1COCCO1,,CCN(CC)CC,,test
US03944560,CC(C)N1CC2(COc3ccc([N+](=O)[O-])cc3OC2)OC1c1ccccc1>>CC(C)N1CC2(COc3ccc(N)cc3OC2)OC1c1ccccc1,[Pd],CCOC(C)=O,,[H][H],,test
US20100210631A1,CC(C)(C)OC(=O)C(CN)c1cccc(O)c1.CCCCBr>>CCCCOc1cccc(C(CN)C(=O)OC(C)(C)C)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06013649,CCCC[Mg]Cl.COc1ccc(S(=O)(=O)CCC=O)cc1>>CCCCC(O)CCS(=O)(=O)c1ccc(OC)cc1,,C1CCOC1,O,CCOC(C)=O,[Cl-].[NH4+],test
US05360795,O=P(Cl)(Cl)Cl.O=S(=O)(O)c1nc2cc(Cl)c(Cl)cc2[nH]1>>Clc1nc2cc(Cl)c(Cl)cc2[nH]1,,O=P(Cl)(Cl)Cl,,ClP(Cl)(Cl)(Cl)Cl,,test
US20150197511A1,N#Cc1ccc(N)cc1Cl.O=C(Cl)Oc1ccccc1>>N#Cc1ccc(NC(=O)Oc2ccccc2)cc1Cl,,C1CCOC1,,CCOC(C)=O,c1ccncc1,test
US20060155128A1,CCOc1cc(F)c([N+](=O)[O-])cc1F>>CCOc1cc(F)c(N)cc1F,[Pd],CCO,,,,test
US20070244131A1,COc1nc(Cl)cc(-c2ccc3nc(NC(C)=O)sc3c2)n1.NCCc1ccc(Cl)cc1Cl>>COc1nc(NCCc2ccc(Cl)cc2Cl)cc(-c2ccc3nc(NC(C)=O)sc3c2)n1,,CN1CCCC1=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050182138A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)C[C@H](N)[C@@H](O)CC(=O)O>>CC(C)C[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)O,,ClCCl,,CCN(CC)CC,,test
US20080039457A1,COc1ccc(C2(C(=O)Cl)CC2)cc1.NNc1nnc(-c2ccccc2)c(=O)[nH]1>>COc1ccc(C2(c3nnc4[nH]c(=O)c(-c5ccccc5)nn34)CC2)cc1,,CO,c1ccncc1,,,test
US20130231478A1,CCC(c1cccc(OC)c1)C(C)C(=O)N(C)C>>CCC(c1cccc(OC)c1)C(C)CN(C)C,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100324106A1,Fc1cc(-n2ccc3c(OCc4ccccc4)c(F)cc(Br)c32)ccc1OCc1ccccc1>>Oc1ccc(-n2ccc3c(O)c(F)cc(Br)c32)cc1F,[Pd],CCOC(C)=O,,,,test
US05212320,CC(C)(C)OC(=O)N(Cc1ccccc1)c1cccc(C(=O)c2cn(CCCC(=O)OCc3ccccc3)c3ccccc23)c1>>O=C(CCCn1cc(C(=O)c2cccc(NCc3ccccc3)c2)c2ccccc21)OCc1ccccc1,,C1COCCO1,,Cl,,test
US20080015203A1,CC(C)(C)OC(=O)n1ccc(N)n1.CC(C)[Si](OC[C@H](C)Oc1cc(OCc2ccccc2)cc(C(=O)O)c1)(C(C)C)C(C)C>>CC(C)[Si](OC[C@H](C)Oc1cc(OCc2ccccc2)cc(C(=O)Nc2ccn(C(=O)OC(C)(C)C)n2)c1)(C(C)C)C(C)C,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090221774A1,C=CCCl.CCCCCC.CN(C)C=O.c1ccc2c(c1)Cc1ccccc1-2>>C=CCC1(CC=C)c2ccccc2-c2ccccc21,,CCCCCC,O,CC(C)(C)[O-].[K+],,test
US20060135578A1,COc1cc(C=O)ccc1O.Cc1nc(-c2ccccc2)sc1CCl>>COc1cc(C=O)ccc1OCc1sc(-c2ccccc2)nc1C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140163012A1,COc1cc(C=Cc2ccc(F)cn2)ccn1>>COc1cc(CCc2ccc(F)cn2)ccn1,[Pd],CO,,[H][H],,test
US20160024049A1,BrCc1ccccc1.Cc1ccc(-c2ccncc2)c(C(=O)N2CCNC(=O)C2)c1>>Cc1ccc(-c2ccncc2)c(C(=O)N2CCN(Cc3ccccc3)C(=O)C2)c1,,O,,CN(C)C=O,[H-].[Na+],test
US05300639,CCCCCBr.COc1ccc(C=Cc2nc3c(s2)NCCCC3)cc1O>>CCCCCOc1cc(C=Cc2nc3c(s2)NCCCC3)ccc1OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04194044,O=CC(Cl)(Cl)Cl.c1ccc(Oc2ccc(CC3NCCC4=C3CCCC4)cc2)cc1>>O=CN1CCC2=C(CCCC2)C1Cc1ccc(Oc2ccccc2)cc1,,ClC(Cl)Cl,,,,test
US20070155720A1,Cc1cccc(C(=O)O)c1.O=C(Cl)C(=O)Cl>>Cc1cccc(C(=O)Cl)c1,CN(C)C=O,c1ccccc1,,,,test
US20110195110A1,CC(C)(C)c1cc(NC(=O)Oc2ccccc2)n(-c2cccc(F)c2)n1.CNC(=O)c1cc(Oc2ccc(N)c(C(F)(F)F)c2)ccn1>>CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3cccc(F)c3)c(C(F)(F)F)c2)ccn1,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US20160137653A1,CCOC(=O)C(CC)[C@@H]1CC[C@@H](O)CC1.Oc1ccncc1>>CCOC(=O)C(CC)[C@@H]1CC[C@H](Oc2ccncc2)CC1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030174377A1,CN(C)C=O.c1[nH]cc2c1OCCO2>>O=Cc1[nH]cc2c1OCCO2,,ClCCl,,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US20100210524A1,O=C1C=CC(=O)C1.O=S1(=O)CC=CC1>>O=C1CC(=O)C2CC=CCC12,,Cc1ccccc1,,,,test
US20060041020A1,O=C1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1>>C=C(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1,,CO,,[BH4-].[Na+],,test
US20120184522A1,O=CN1CCC(n2c(=O)n(Cc3ccc(Cl)cc3)c(=O)c3cc(OCC(F)F)ccc32)CC1>>O=c1[nH]c(=O)n(C2CCNCC2)c2ccc(OCC(F)F)cc12,,O=CO,,,,test
US20110044899A1,CCN(CCNC(=O)c1cnc2cc(I)ccc2n1)CCOc1cccnc1F.Cl.ClCCl>>CCN(CCNC(=O)c1cnc2cc(I)ccc2n1)CCOc1cccnc1F.Cl.Cl,,CCOCC,ClCCl,,,test
US03932301,Cc1ccc(C(=O)CCl)cc1.Oc1ccc2oc3ccccc3c2c1>>Cc1ccc(C(=O)COc2ccc3oc4ccccc4c3c2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090285782A1,OB(O)c1ccc(F)cc1.Oc1ncnc2ccc(Br)cc12>>Oc1ncnc2ccc(-c3ccc(F)cc3)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,CC(=O)O,O=C([O-])[O-].[K+].[K+],test
US20040053957A1,Cc1cc(CO)c2c(N)c(C(N)=O)sc2n1.Oc1ccccc1>>Cc1cc(COc2ccccc2)c2c(N)c(C(N)=O)sc2n1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060135517A1,CCCNn1ccnc1.Cc1cccc(-c2nc3ccccn3c2-c2ccnc(S(C)(=O)=O)n2)n1>>Cc1cccc(-c2nc3ccccn3c2-c2ccnc(NCCCn3ccnc3)n2)n1,,CC#N,,,,test
US20080255197A1,C[Si](C)(C)N=C=O.Cc1cnc(CN(CCCCN)[C@@H](C)c2ccccn2)c(C)c1>>Cc1cnc(CN(CCCCNC(N)=O)[C@@H](C)c2ccccn2)c(C)c1,,CC(C)O,,,,test
US20090233901A1,Cc1ccc(S(=O)(=O)OC[C@@H](O)[C@H](O)COS(=O)(=O)c2ccc(C)cc2)cc1.NCc1ccccc1>>O[C@@H]1CN(Cc2ccccc2)C[C@H]1O,,C1COCCO1,,O=C([O-])O.[Na+],,test
US20060002991A1,CCCCCCCCCCCCCCCC(=O)C(O)C(O)C(O)C(=O)CCCCCCCCCCCCCCC.NCCc1c[nH]cn1.O=C(O)CCC(=O)O>>CCCCCCCCCCCCCCCC(=O)C(O)C(O)C(O)C(=O)CCCCCCCCCCCCCCC.NCCc1c[nH]cn1.O=C(O)CCC(=O)O,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US05849801,CC(=O)OC(C)=O.CC1=CC(NCc2ccccc2)C(O)C(C)(C)CC1=O>>CC(=O)N(Cc1ccccc1)C1C=C(C)C(=O)CC(C)(C)C1O,,C1CCOC1,,CCN(CC)CC,,test
US20140179733A1,C=CCC(C(=O)OCC)n1c(C)nc(C(F)(F)F)c1C=C.CC(C)c1c(N)cnn1-c1ccc(Cl)cc1>>Cc1nc(C(F)(F)F)cn1[C@@H](C)C(=O)Nc1cnn(-c2ccc(Cl)cc2)c1C(C)C,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050154185A1,COC(=O)C(CN)NS(=O)(=O)c1c(C)cc(OCCCC(=O)NCCCOCCOCCOCCCNC(=O)OCc2ccccc2)cc1C.O=C(O)c1ccc2c(cnn2CCCNc2nccn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1>>COC(=O)C(CNC(=O)c1ccc2c(cnn2CCCNc2nccn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1)NS(=O)(=O)c1c(C)cc(OCCCC(=O)NCCCOCCOCCOCCCNC(=O)OCc2ccccc2)cc1C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04670447,CC(=O)N1CCC(C(=O)c2ccc(F)cc2F)CC1.CNN>>CC(=O)N1CCC(c2nn(C)c3cc(F)ccc23)CC1,,CCCCO,,,,test
US20130336920A1,CC(C)Oc1ccc([N+](=O)[O-])c(-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1>>CC(C)Oc1ccc(N)c(-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1,[Pd],CO,ClCCl,,,test
US20020156081A1,CC(C)(Cc1ccccc1)C(=O)Cl.COc1cc(-c2nn([C@@H]3CC[C@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1N>>COc1cc(-c2nn([C@@H]3CC[C@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)C(C)(C)Cc1ccccc1,,c1ccncc1,,O=C([O-])O.[Na+],,test
US20050165001A1,CC(C)(C)OC(=O)N1CCNCC1.COc1cc([N+](=O)[O-])c(C#N)c([N+](=O)[O-])c1>>COc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)c(C#N)c([N+](=O)[O-])c1,,CN(C)C=O,,,,test
US20140275085A1,CCN.COc1nc(Cl)ncc1Br>>CCNc1ncc(Br)c(OC)n1,,C1CCOC1,O,,,test
US20030055056A1,C=C(C)COc1ccc2c(=O)c(C)c(-c3ccccc3)oc2c1C(C)=O.COc1cc(C=O)cc(OC)c1OC>>C=C(C)COc1ccc2c(=O)c(C)c(-c3ccccc3)oc2c1C(=O)C=Cc1cc(OC)c(OC)c(OC)c1,,CCO,O,[K+].[OH-],,test
US04055639,O=C(NC(O)C(Cl)(Cl)Cl)c1cc(Cl)ccc1O>>O=C(NC=C(Cl)Cl)c1cc(Cl)ccc1O,[Zn],CC(=O)O,,,,test
US05041679,CC(=O)CC(O)CC(C)Sc1cccc(F)c1>>CC(=O)C=CCC(C)Sc1cccc(F)c1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20130029846A1,CCN(C)C=Nc1ccc2[nH]ccc2c1.ClCc1ccc(Cl)c(Cl)c1>>CCN(C)C=Nc1ccc2c(ccn2Cc2ccc(Cl)c(Cl)c2)c1,C1COCCOCCOCCOCCOCCO1,CS(C)=O,,O,CC(C)(C)[O-].[K+],test
US20060106084A1,CCCI.COc1cccc(C(=O)c2n[nH]c3c(C(F)(F)F)cccc23)c1>>CCCn1nc(C(=O)c2cccc(OC)c2)c2cccc(C(F)(F)F)c21,,CN(C)C=O,,[H-].[Na+],,test
US20080039457A1,CN(CCNC(=O)OC(C)(C)C)c1ccccn1.O=C(O)C(F)(F)F>>CN(CCN)c1ccccn1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20140171390A1,CC(=O)OCC[C@@H]1CC[C@@H](C(CCN=[N+]=[N-])NC(=O)OC(C)(C)C)CC1>>CC(=O)OCC[C@@H]1CC[C@@H](C(CCN)NC(=O)OC(C)(C)C)CC1,[Pd],CO,,,,test
US20120010186A1,Cc1ccc(Cl)cc1N1CC2CN(c3ncc(-c4nnn(CC(=O)OC(C)(C)C)n4)s3)CC2C1>>Cc1ccc(Cl)cc1N1CC2CN(c3ncc(-c4nnn(CC(=O)O)n4)s3)CC2C1,,CO,,C1CCOC1,[Li+].[OH-],test
US20110190329A1,C#CCNCc1ccccc1.CC(C)(C)C(=O)Cl>>C#CCN(Cc1ccccc1)C(=O)C(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20090105275A1,CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(C)n2)c1>>CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(C2CCCC(C)N2)c1,O=[Pt],CO,,C1COCCO1,Cl,test
US20120225866A1,CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(CN)ccc21.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(CNS(=O)(=O)c3ccccc3[N+](=O)[O-])ccc21,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20050014812A1,CCOC(=O)CCCOc1cc(C)c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c([N+](=O)[O-])c1>>CCOC(=O)CCCOc1cc(C)c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(N)c1,[Pd],CCO,,[H][H],,test
US20150329538A1,CC(O)C(F)(F)F.O=C1NCCc2[nH]c(-c3cccc4ccc(Cl)nc34)cc21>>CC(Oc1ccc2cccc(-c3cc4c([nH]3)CCNC4=O)c2n1)C(F)(F)F,,CN(C)C=O,ClCCl,CO,[H-].[Na+],test
US20150291636A1,CC(C)[Si](OC[C@@H](OCc1ccccc1)[C@@H](OCc1ccccc1)[C@H](CN(C=O)OCc1ccccc1)OCc1ccccc1)(C(C)C)C(C)C>>O=CN(C[C@H](OCc1ccccc1)[C@H](OCc1ccccc1)[C@@H](CO)OCc1ccccc1)OCc1ccccc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100130558A1,CC(C)C[C@H](N)C(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CC(C)C[C@H](NS(C)(=O)=O)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,Cl,test
US20080287399A1,Cc1nc2cc(Br)ccc2s1.O=Cc1cccc(B(O)O)c1>>Cc1nc2cc(-c3cccc(C=O)c3)ccc2s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20040077669A1,CC#CCOc1cc(Cl)ncn1.CCCNCCC>>CC#CCOc1cc(N(CCC)CCC)ncn1,,CCOC(C)=O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20060030600A1,CC(C)(C)[SiH2]OC(C)(C)c1cncc(OCc2ccccc2)c1>>CC(C)(C)[SiH2]OC(C)(C)c1cncc(O)c1,[Pd],CO,,,,test
US04889858,C1CNCCN1.Fc1ccc2c(c1)C(Cl)c1ccccc1CO2>>Fc1ccc2c(c1)C(N1CCNCC1)c1ccccc1CO2,,ClC(Cl)Cl,,[Na+].[OH-],,test
US20150329538A1,COC(=O)c1cc(-c2cccc3nc(C)c(NC(C)(C)C)nc23)[nH]c1C(C)NC(=O)OC(C)(C)C>>Cc1nc2cccc(-c3cc4c([nH]3)C(C)N(C(=O)OC(C)(C)C)C4=O)c2nc1NC(C)(C)C,,C1COCCO1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04347371,O=C(O)[C@@H]1CSC(c2ccccc2O)N1.O=C1CCSSCCC(=O)O1>>O=C(O)CCSSCCC(=O)N1C(c2ccccc2O)SC[C@H]1C(=O)O,,CC(C)=O,,CCN(CC)CC,,test
US20060160864A1,CCCCOCCOc1ccc(-c2ccc(N3CCC(C)CC3)c(/C=C/C(=O)O)c2)cc1.CCCn1cncc1C[S@](=O)c1ccc(N)cc1>>CCCCOCCOc1ccc(-c2ccc(N3CCC(C)CC3)c(/C=C/C(=O)Nc3ccc([S@@](=O)Cc4cncn4CCC)cc3)c2)cc1,CN(C)C=O,C1CCOC1,O,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20050267149A1,COC(=O)c1ccccc1SCCc1cccc(OC(C)(C)C)c1>>COC(=O)c1ccccc1SCCc1cccc(O)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04371526,CC(C)(C)C(=O)OCOP(=O)(CCCCc1ccccc1)CC(=O)N1N=C(c2ccccc2)CC1C(=O)OCc1ccccc1>>CC(C)(C)C(=O)OCOP(=O)(CCCCc1ccccc1)CC(=O)N1N=C(c2ccccc2)CC1C(=O)O,[Pd],CO,,[H][H],,test
US20030166644A1,CNc1cccc(C)c1.O=C(Cl)OC(Cl)(Cl)Cl.Oc1nccc(C(F)(F)F)n1>>Cc1cccc(N(C)C(=O)Oc2nccc(C(F)(F)F)n2)c1,,C1CCOC1,,,,test
US04877790,C=CCN1CCNCC1.CCSc1nc2ccccc2c(=O)[nH]1>>C=CCN1CCN(c2nc3ccccc3c(=O)[nH]2)CC1,,CCOC(C)=O,,,,test
US20050250836A1,O=Cc1c(Br)c2c3c(c(-c4ccccc4Cl)cc2n1CCCO)C(=O)NC3=O>>O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c(Br)c(CO)n1CCCO,,C1CCOC1,,CSC,,test
US20140323464A1,COc1cc(Nc2nc(NCC3CCN(C(=O)CC#N)CC3)n3ccnc3c2C(N)=O)cc(OC)c1.O=CC1CC1>>COc1cc(Nc2nc(NCC3CCN(C(=O)C(C#N)=CC4CC4)CC3)n3ccnc3c2C(N)=O)cc(OC)c1,,CCO,,C1CCNCC1,CC(=O)O,test
US20120252777A1,COC(=O)c1cccc(B2OC(C)(C)C(C)(C)O2)c1.COCC1CCCN1c1cccc(Nc2nc(Cl)nc3scnc23)c1>>COCC1CCCN1c1cccc(Nc2nc(-c3cccc(C(=O)OC)c3)nc3scnc23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20140336377A1,CCC(=O)Nc1cc(C(=O)OC)ccn1>>CCC(=O)Nc1cc(C(=O)O)ccn1,,CO,,[Na+].[OH-],,test
US04925849,CCC1CCCCN1.O=C(O)C=Cc1c(-c2ccccc2)nn2ccccc12>>CCC1CCCCN1C(=O)C=Cc1c(-c2ccccc2)nn2ccccc12,,C1CCOC1,ClCCl,CC(C)COC(=O)Cl,CCN(CC)CC,test
US20060142385A1,CC(C)CCOc1ccc(NCC(=O)OC(C)(C)C)cc1.CS(=O)(=O)Cl>>CC(C)CCOc1ccc(N(CC(=O)OC(C)(C)C)S(C)(=O)=O)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20080027049A1,CC(C)CC(=O)Cl.Nc1ccc2oc3c(c2c1)CCCCCC3>>CC(C)CC(=O)Nc1ccc2oc3c(c2c1)CCCCCC3,,c1ccncc1,,,,test
US20020193578A1,C=C(OCC)c1ccc(O[Si](C(C)C)(C(C)C)C(C)C)cc1C(C)C.ICI>>CCOC1(c2ccc(O[Si](C(C)C)(C(C)C)C(C)C)cc2C(C)C)CC1,[Zn],,,,,test
US20160024103A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2nc(Cl)c(Br)cc12.COc1ccc(B(O)O)cc1C(=O)O>>CNC(=O)c1c(-c2ccc(F)cc2)oc2nc(Cl)c(-c3ccc(OC)c(C(=O)O)c3)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150152080A1,COC(=O)c1ccccc1CSc1ccc(F)cc1NS(=O)(=O)c1cc2ccccc2s1>>O=C(O)c1ccccc1CSc1ccc(F)cc1NS(=O)(=O)c1cc2ccccc2s1,,CO,,Cl,[Na+].[OH-],test
US20080119518A1,C=O.COc1ccc(C(=O)N2CCNCC2)cc1CCN1CCC(n2ccc3ccc(C(N)=O)cc32)CC1>>COc1ccc(C(=O)N2CCN(C)CC2)cc1CCN1CCC(n2ccc3ccc(C(N)=O)cc32)CC1,,CC#N,CC(=O)O,[BH3-]C#N.[Na+],,test
US03974158,CCOc1ccccc1N.Cc1ccc(S(=O)(=O)OCC2CN(Cc3ccccc3)CCO2)cc1>>CCOc1ccccc1NCC1CN(Cc2ccccc2)CCO1.Cc1ccc(S(=O)(=O)O)cc1,,CCOCC,,,,test
US20070213341A1,C=C(N=Cc1ccccc1C)O[Si](C)(C)C.CCOC(=O)N1C(=O)/C(=C\c2cccc(Cl)c2)c2ccc(Cl)cc21>>CCOC(=O)N1C(=O)C2(c3ccc(Cl)cc31)C(c1cccc(Cl)c1)CC(=O)NC2c1ccccc1C,,Cc1ccccc1,,,,test
US20120015962A1,Nc1cc(Cl)ccc1OC1CCC(O)CC1.O=C(O)c1cnn2cccnc12>>O=C(Nc1cc(Cl)ccc1OC1CCC(O)CC1)c1cnn2cccnc12,,CC#N,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04864052,COC(=O)C1C(C=O)C1(C)C.FC(F)(F)C(Cl)(Cl)Cl>>COC(=O)C1C(C(O)C(Cl)(Cl)C(F)(F)F)C1(C)C,[Zn],CN(C)C=O,,[Cl-].[NH4+],,test
US20090163488A1,CCn1cc(C(=O)O)c(C(F)(F)F)c1.Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)c1>>CCn1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)nn4c3)c2)c(C(F)(F)F)c1,CN(C)C=O,CC(=O)N(C)C,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US20040102433A1,C=CCOC(=O)N1CC(=O)C(C(=O)OC(C)(C)C)C[C@H]1C>>C=CCOC(=O)N1CC(O)C(C(=O)OC(C)(C)C)C[C@H]1C,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20040116464A1,CC1(C)OCC(Cn2cc(C(=O)NCc3ccc(Cl)cc3)c(=O)c3cc(CCl)sc32)O1.CNC[C@@H](O)c1ccccc1>>CN(Cc1cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(CC3COC(C)(C)O3)c2s1)C[C@@H](O)c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06013658,CN(C(=O)OC(C)(C)C)[C@@H](COCCO)Cc1ccccc1>>CN[C@@H](COCCO)Cc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05830912,CC(O)c1cc(F)c(OCc2ccccc2)c(F)c1OCc1ccccc1>>CC(=O)c1cc(F)c(OCc2ccccc2)c(F)c1OCc1ccccc1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US06114390,CCOC(=O)Cn1cc(CC(=O)OCc2ccccc2)c2ccccc21>>CCOC(=O)Cn1cc(CC(=O)O)c2ccccc21,[Pd],C1CCOC1,,,,test
US20070093521A1,CCOc1cc(C=O)ccc1OC.CCOc1cc(CN2CCC(Nc3nc4ccc(C(=O)OC)cc4o3)CC2)ccc1O>>CCOc1cc(CN2CCC(Nc3nc4ccc(C(=O)OC)cc4o3)CC2)ccc1OC,,CC(=O)O,CCO,CCN(C(C)C)C(C)C,[BH3-]C#N.[Na+],test
US20030105151A1,COc1ccccc1B(O)O.O=[N+]([O-])c1cc(Br)ccc1F>>COc1ccccc1-c1ccc(F)c([N+](=O)[O-])c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US05250522,O=C(OCc1ccccc1)[C@H](Cc1ccc(-c2ccccc2)cc1)NCP(=O)(Oc1ccccc1)Oc1ccccc1>>O=C(O)[C@H](Cc1ccc(-c2ccccc2)cc1)NCP(=O)(Oc1ccccc1)Oc1ccccc1,[Pd],CCOC(C)=O,,[H][H],,test
US20080275037A1,C[Mg]Br.Cc1ncc(C=O)cn1>>Cc1ncc(C(C)O)cn1,,C1CCOC1,,,,test
US20090149439A1,Cc1cc(Br)ncc1Br.O=Cc1c(F)ccc(F)c1F>>Cc1cc(Br)ncc1C(O)c1c(F)ccc(F)c1F,,CCCCCC,CCOCC,[Li]CCCC,[Cl-].[NH4+],test
US20070054915A1,C1COCCO1.Nc1n[nH]c2nc(Oc3ccc(F)cc3F)ncc12.O=C(Cl)C1CC1>>O=C(Nc1n[nH]c2nc(Oc3ccc(F)cc3F)ncc12)C1CCCC1,,C1COCCO1,,c1ccncc1,,test
US20050148624A1,CS(=O)(=O)c1ccc(Cn2c(C=O)c(-c3ccccc3)c3cc(Br)ccc3c2=O)cc1.C[Si](C)(C)C(F)(F)F>>CS(=O)(=O)c1ccc(Cn2c(C(O)C(F)(F)F)c(-c3ccccc3)c3cc(Br)ccc3c2=O)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20070244159A1,CC(=O)Cl.CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c(F)cc2n1CCN>>CC(=O)NCCn1c(C(C)(C)C)cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c(F)cc21,,CN(C)C=O,,CCN(CC)CC,,test
US20030236287A1,CCOC(=O)c1cc(Cl)on1>>O=C(O)c1cc(Cl)on1,,CCO,,[Li+].[OH-],,test
US20080200454A1,COC(=O)[C@@H]1Cc2ccc(C#Cc3cc(-c4nn(CCCN5CCOCC5)c5c4CN(S(C)(=O)=O)CC5)ccc3Cl)cc2CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1Cc2ccc(C#Cc3cc(-c4nn(CCCN5CCOCC5)c5c4CN(S(C)(=O)=O)CC5)ccc3Cl)cc2CN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090054478A1,Cc1cc(Cl)nc2[nH]nc(O)c12.O=C=NCCc1cccs1>>Cc1cc(Cl)nc2[nH]n(C(=O)NCCc3cccs3)c(=O)c12,,C1CCOC1,,,,test
US04605740,COC(=O)C1CC2C=CC1O2.Nc1ccccc1>>C=CC(=O)Nc1ccccc1,,O,,Cl,,test
US04331676,CC(=O)S[C@@H]1CC(=O)N1C(O)C(=O)OCc1ccc([N+](=O)[O-])cc1.O=S(Cl)Cl>>CC(=O)S[C@@H]1CC(=O)N1C(Cl)C(=O)OCc1ccc([N+](=O)[O-])cc1,,C1COCCO1,,,,test
US20080306082A1,Fc1cnc(Cl)nc1Cl.O=C(O)c1cccc2sc(B(O)O)cc12>>O=C(O)c1cccc2sc(-c3nc(Cl)ncc3F)cc12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US06265434B1,CC(C)(C)OC(=O)N1CCC(CCCc2ccc(F)cc2F)CC1>>Fc1ccc(CCCC2CCNCC2)c(F)c1,,CO,Cl,,,test
US20100016319A1,C1COCCN1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(C)ccc2Oc2ccnc(Cl)n2)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(C)ccc2Oc2ccnc(N3CCOCC3)n2)cc1,,CCO,,,,test
US04689070,CSC(=NS(=O)(=O)c1ccccc1Cl)Nc1nc(C)cc(C)n1.NO>>Cc1cc(C)nc(NC(=NO)NS(=O)(=O)c2ccccc2Cl)n1,,C1CCOC1,,Cl,CC(=O)[O-].[Na+],test
US20150025291A1,CCCCI.c1cc(N2CCCC2)ccn1>>CCCC[n+]1ccc(N2CCCC2)cc1.[I-],,CCO,,,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(O[Si](C)(C)C(C)(C)C)C(F)F)CC2)c2ncnn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(O)C(F)F)CC2)c2ncnn12,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US20040259912A1,CCC(=O)c1cc([N+](=O)[O-])ccc1OCc1ccccc1Cl>>CCC(=O)c1cc(N)ccc1OCc1ccccc1Cl,,CO,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US03964896,COC(=O)Cl.NC(=O)c1ccccc1C(=O)O>>COC(=O)c1ccccc1C#N,,ClCCl,,CCN(CC)CC,,test
US20100256097A1,CC(C)(O[Si](C)(C)C(C)(C)C)c1ccc(-c2cc(C(N)=O)c([N+](=O)[O-])s2)cn1>>CC(C)(O)c1ccc(-c2cc(C(N)=O)c([N+](=O)[O-])s2)cn1,,C1CCOC1,O,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20160229864A1,COc1ncnc2c(-c3ccc(F)cc3)csc12>>O=c1[nH]cnc2c(-c3ccc(F)cc3)csc12,,C1COCCO1,O,Cl,,test
US20110224204A1,Cc1cc(B(O)O)ccn1.O=S(=O)(Oc1ccccc1-c1ccc(OCc2ccc3ccccc3n2)cc1)C(F)(F)F>>Cc1cc(-c2ccccc2-c2ccc(OCc3ccc4ccccc4n3)cc2)ccn1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20090099158A1,O=C(Cl)c1ccccc1.O=C(c1ccc2c(c1)CCNC2)N1CCN(C2CCC2)CC1>>O=C(c1ccc2c(c1)CCN(C(=O)c1ccccc1)C2)N1CCN(C2CCC2)CC1,,ClCCl,,,,test
US20100311966A1,CCCCOC(=O)C(=O)C(C)Br.CO[C@@H]1CN(C(N)=O)CC[C@@H]1NC(=O)OCc1ccccc1>>CCOC(=O)c1nc(N2CC[C@H](NC(=O)OCc3ccccc3)[C@H](OC)C2)oc1C,,C1CCOC1,,O=C([O-])O.[Na+],,test
US06514968B1,CC(Br)Br.Oc1cccc2c1c1ccccc1n2Cc1ccccc1>>BrCCOc1cccc2c1c1ccccc1n2Cc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090042925A1,CC(C)(C)OC(=O)NCCCn1c(CCl)nc2c(N)nc3ccccc3c21.O=C1c2ccccc2C(=O)N1O>>CC(C)(C)OC(=O)NCCCn1c(CON2C(=O)c3ccccc3C2=O)nc2c(N)nc3ccccc3c21,,CN(C)C=O,O,CCN(CC)CC,,test
US20090054654A1,N#Cc1ccccc1-c1cc(-c2ccccn2)cn(-c2ccccc2)c1=O.O=S(=O)(O)c1ccccc1>>N#Cc1ccccc1-c1cc(-c2ccccn2)cn(-c2ccccc2)c1=O.O=S(=O)(O)c1ccccc1,,CC(C)O,,CC(C)=O,,test
US20050004114A1,CN(C)c1nc(Cl)nc(N(C)C)n1.O=C(O)CCC(=O)c1c[nH]c2ccc(Br)cc12>>CN(C)c1nc(N(C)C)nc(-n2cc(C(=O)CCC(=O)O)c3cc(Br)ccc32)n1,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20120232056A1,COC(=O)c1ccc2nc(-c3c[nH]nc3C(F)(F)F)c(N(C)C(C)C)nc2c1>>CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1c[nH]nc1C(F)(F)F,,CO,,O,[Na+].[OH-],test
US06350762B1,C=C1CC(=O)O1.NCC=Cc1ccccc1>>CC(=O)CC(=O)NCC=Cc1ccccc1,,Cc1ccccc1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20130172549A1,O=C(NCC12CC3CC(CC(C3)C1)C2)c1cccc2nc(CCN3C(=O)c4ccccc4C3=O)cn12>>NCCc1cn2c(C(=O)NCC34CC5CC(CC(C5)C3)C4)cccc2n1,,CCO,,NN,,test
US20150057443A1,NCC(=O)C1(c2ccc(Cl)c(Cl)c2)CCC1>>NCC(O)C1(c2ccc(Cl)c(Cl)c2)CCC1,,CCO,,[BH4-].[Na+],,test
US05202335,C=[N+]=[N-].O=C(O)/C(=C/c1ccccc1)CC(=O)N1C[C@@H]2CCCC[C@@H]2C1>>COC(=O)/C(=C/c1ccccc1)CC(=O)N1C[C@@H]2CCCC[C@@H]2C1,,CCOCC,,,,test
US04827011,CC(=O)O.CCCCCCCCCCCCCCCCOC(C)C1CO1>>CCCCCCCCCCCCCCCCOC(C)C(O)CO,,CC(=O)O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090029958A1,CC(C)(C)[Si](C)(C)O[C@@H](CNC1CCN(CCC(=O)O)CC1)c1ccc(O)c2[nH]c(=O)ccc12.c1ccc(CNCc2ccccc2)cc1>>O=C(CCN1CCC(NC[C@H](O)c2ccc(O)c3[nH]c(=O)ccc23)CC1)N(Cc1ccccc1)Cc1ccccc1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100093727A1,CN1[C@H](CO)CCC12CC2.CS(=O)(=O)Cl>>CN1[C@H](COS(C)(=O)=O)CCC12CC2,,ClCCl,,CCN(CC)CC,,test
US03974176,O=Cc1c(-c2ccc(Cl)cc2)nn(-c2ccccc2)c1Cl>>OCc1c(-c2ccc(Cl)cc2)nn(-c2ccccc2)c1Cl,,CN(C)C=O,O,[BH4-].[Na+],,test
US05288776,C1=C(c2ccccc2)N1.CCC(=O)CC(=O)c1ccccc1>>CCc1[nH]cc(-c2ccccc2)c1C(=O)c1ccccc1,,CCO,,,,test
US20120157428A1,Clc1ccc([Mg]Br)cc1.O=Cc1c(I)ccnc1F>>OC(c1ccc(Cl)cc1)c1c(I)ccnc1F,,C1CCOC1,,,,test
US20070197551A1,CCOC(=O)C1=C(N)CCCC1.O=C(Cl)CCCCBr>>CCOC(=O)C1=C(NC(=O)CCCCBr)CCCC1,,C1CCOC1,,CCOC(C)=O,c1ccncc1,test
US20090253656A1,CCN(CC)C(=O)Cl.COc1ccc(/C(C#N)=C/c2ccc(N3CCC(O)CC3)s2)cc1OC>>CCN(CC)C(=O)OC1CCN(c2ccc(/C=C(\C#N)c3ccc(OC)c(OC)c3)s2)CC1,,c1ccncc1,,CO,,test
US20060293299A1,CC(C)N.CC(OC(=O)Oc1ccc([N+](=O)[O-])cc1)C(=C1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1)c1cc(F)cc(F)c1>>CC(C)NC(=O)OC(C)C(=C1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1)c1cc(F)cc(F)c1,,ClCCl,,,,test
US20090270445A1,COc1ccc(CC(N)CNc2ncc(-c3ccc4[nH]c(=O)oc4c3)s2)cc1F>>NC(CNc1ncc(-c2ccc3[nH]c(=O)oc3c2)s1)Cc1ccc(O)c(F)c1,,ClCCl,,BrB(Br)Br,,test
US04140789,CC(C)(C)NCC(O)COc1cccc([N+](=O)[O-])c1C#N>>CC(C)(C)NCC(O)COc1cccc(N)c1C(N)=O,[Ni],CCO,,NN,O,test
US06002008,CN(C)C=O.COC(=O)c1ccccc1N>>COC(=O)c1ccccc1N=CN(C)C,,ClCCl,,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US20100152207A1,CS(=O)(=O)Cl.OCCOc1ccccn1>>CS(=O)(=O)OCCOc1ccccn1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20100226881A1,CCOC(=O)c1c(C)nn2ccc(C)cc12>>Cc1ccn2nc(C)cc2c1,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20120319052A1,CC1(C)c2ccccc2N2c3ccccc3Sc3cccc1c32.O=C1CCC(=O)N1Br>>CC1(C)c2ccccc2N2c3ccccc3Sc3cc(Br)cc1c32,,ClC(Cl)Cl,,,,test
US06809097B1,COc1cc2c(=O)cc[nH]c2cc1OCCCN1CCOCC1.O=S(Cl)Cl>>COc1cc2c(Cl)ccnc2cc1OCCCN1CCOCC1.Cl,CN(C)C=O,,,,,test
US05391771,CCCCO.CCO.O=C(O)CC(O)(CC(=O)O)C(=O)O>>OCC1CCOCC1.OCCC1CCOC1,,CCCCO,,[H][H],,test
US20080280855A1,Cc1ccccc1C(=O)CCc1c(C(=O)N(C)C)cc2c(nc(C)n2C)c1O.O=C(O)C(=O)O>>Cc1ccccc1[C@H](O)CCc1c(C(=O)N(C)C)cc2c(nc(C)n2C)c1O.O=C(O)C(=O)O,,CC(C)O,,CC(C)(C)[O-].[K+],,test
US05340811,Cc1ccc(S(=O)(=O)OCCNS(=O)(=O)c2cccc3cnccc23)cc1.NCc1ccc2c(c1)OCO2>>O=S(=O)(NCCNCc1ccc2c(c1)OCO2)c1cccc2cnccc12,,C1CCOC1,,,,test
US04218476,Cc1cc(C)c(N)c(C)c1.O=S(=O)(Cl)OCCBr>>C=CS(=O)(=O)Nc1c(C)cc(C)cc1C,,CCOCC,,CCN(CC)CC,,test
US04822790,CON=C(C(=O)N[C@@H]1C(=O)N[C@H]1OC(C)=O)c1csc(NC(=O)CCl)n1.[N-]=[N+]=[N-]>>CON=C(C(=O)N[C@@H]1C(=O)NC1N=[N+]=[N-])c1csc(NC(=O)CCl)n1,,CN(C)C=O,,O,,test
US20050267018A1,CCOC(=O)[C@@]12C[C@H]1C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](OC(=O)N3Cc4ccccc4C3)C[C@H]1C(=O)N2>>CC(C)(C)OC(=O)N[C@H]1CCCCCC=C[C@@H]2C[C@@]2(C(=O)O)NC(=O)[C@@H]2C[C@@H](OC(=O)N3Cc4ccccc4C3)CN2C1=O,,CO,ClCCl,O,[Li]O,test
US05866586,CI.NC(N)=S.O=[N+]([O-])c1cnc(Cl)c(Cl)c1>>CSc1ncc([N+](=O)[O-])cc1Cl,,CCO,,[Na+].[OH-],,test
US20120322837A1,CCC(CC)CC1C=C(C(=O)O)C1>>CCC(CC)CC1CC(C(=O)O)C1,[Pd],C1CCOC1,,,,test
US20100261755A1,CCOC(=O)CC(=O)[C@@H]1CCN(C(=O)OC)[C@@H](Cc2cc(F)ccc2F)C1.NO>>COC(=O)N1CC[C@@H](c2cc(=O)[nH]o2)C[C@@H]1Cc1cc(F)ccc1F,,CO,O,Cl,[Na+].[OH-],test
US04056540,CN(C)CCCNC(=O)[C@H]1Oc2ccc(Cl)cc2[C@@H](c2ccccc2)O1.Cl>>CN(C)CCCNC(=O)[C@H]1Oc2ccccc2[C@@H](c2ccccc2)O1.Cl,[Pd],CCO,,CCN(CC)CC,,test
US04000153,CCOC(C)(OCC)OCC.NNc1cc(-c2ccccc2F)c2cc(Cl)ccc2n1>>Cc1nnc2cc(-c3ccccc3F)c3cc(Cl)ccc3n12,,Cc1ccccc1C,,,,test
US20090042852A1,CCc1cnc(-c2cnc(N3CCC(C(=O)OC)CC3)c(C)c2)o1>>CCc1cnc(-c2cnc(N3CCC(C(=O)O)CC3)c(C)c2)o1,,CO,,Cl,[Na+].[OH-],test
US20150336949A1,Cc1ccc(S(=O)(=O)n2cc(-c3c(C)nn(Cc4cccc(F)c4)c3C)c3cc(-c4ccc(N5CCN(C(=O)OC(C)(C)C)CC5)cc4)c(C4CC4)nc32)cc1>>Cc1nn(Cc2cccc(F)c2)c(C)c1-c1c[nH]c2nc(C3CC3)c(-c3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)cc3)cc12,,CO,O,[Li+].[OH-],,test
US20080019915A1,COc1ccc(C2(C(=O)O)CC2(C)C)cc1.O=S(Cl)Cl>>COc1ccc(C2(C(=O)Cl)CC2(C)C)cc1,CN(C)C=O,,,,,test
US20120172599A1,CC1=C(C#N)C(=C(C#N)C#N)OC1(C)C.CCCCN(CCCCO)c1ccc(C=Cc2ccc(C=O)s2)c(OCc2ccccc2)c1>>CCCCN(CCCCO)c1ccc(C=Cc2ccc(C=CC3=C(C#N)C(=C(C#N)C#N)OC3(C)C)s2)c(OCc2ccccc2)c1,,C1CCOC1,CCO,C,O=C[O-].[NH4+],test
US05872139,CCCCOc1c(NC(C)(C)CC)c(=O)c1=O.NCc1ccncc1>>CCC(C)(C)Nc1c(NCc2ccncc2)c(=O)c1=O,,C1CCOC1,,,,test
US20120232081A1,CCOC(=O)c1cnn2c(C(=O)N3CCN(C(=O)OC(C)(C)C)CC3)c(Cc3cccc(F)c3C)c(-c3ccccc3)c2c1>>Cc1c(F)cccc1Cc1c(-c2ccccc2)c2cc(C(=O)O)cnn2c1C(=O)N1CCN(C(=O)OC(C)(C)C)CC1,,C1COCCO1,,[Li+].[OH-],,test
US20090270363A1,CCNc1ccc(C#N)cc1.CI>>CCN(C)c1ccc(C#N)cc1,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20130172339A1,COC(=O)c1cccc(N)c1.Cc1c(S(=O)(=O)Cl)sc2ccc(Cl)cc12>>Cc1c(S(=O)(=O)Nc2cccc(C(=O)O)c2)sc2ccc(Cl)cc12,,ClCCl,,c1ccncc1,,test
US20050090534A1,COC(=O)c1oc(C)nc1-c1ccc2c(c1)CCCC2>>Cc1nc(-c2ccc3c(c2)CCCC3)c(CO)o1,,CCOCC,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050020652A1,CCOC(=O)C(C)(C)Oc1ccc(OCCC2CN(Cc3ccc(OC)cc3)C(=O)N2C)cc1>>COc1ccc(CN2CC(CCOc3ccc(OC(C)(C)C(=O)O)cc3)N(C)C2=O)cc1,,CCO,,[Na+].[OH-],,test
US05691335,O=C(Cl)c1ccccc1Oc1ccccc1.O=C1CN(c2ccccc2)C(=O)N1>>O=C1CN(c2ccccc2)C(=O)N1C(=O)c1ccccc1Oc1ccccc1,,c1ccncc1,,,,test
US20070197512A1,CCOC(=O)/C=C/C(=O)N1CC(c2ccccc2)Oc2ccc(Cl)cc21>>O=C(O)/C=C/C(=O)N1CC(c2ccccc2)Oc2ccc(Cl)cc21,,CC(C)(C)O,,Cl,[Na+].[OH-],test
US20100048568A1,COC(=O)c1cnc(-c2cccc(F)c2)nc1>>O=C(O)c1cnc(-c2cccc(F)c2)nc1,,CO,,[Li+].[OH-],,test
US20040167155A1,CCC(=O)OC(=O)CC.Nc1ccccc1-c1ccccc1.c1ccncc1>>CCC(=O)Nc1ccccc1-c1cccc(C)c1,CN(C)c1ccncc1,,,,,test
US20150291563A1,CSc1cccc(B(O)O)c1.OC(C1=NN(c2ccccc2Cl)C(c2ccc(Br)s2)C1)(C(F)(F)F)C(F)(F)F>>CSc1cccc(-c2ccc(C3CC(C(O)(C(F)(F)F)C(F)(F)F)=NN3c3ccccc3Cl)s2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,CCOC(C)=O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20150166483A1,COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(N)c4ccccc34)n2)cc(OC)c1.COc1c(NC(=O)Oc2ccccc2)cc(C(C)(C)C)cc1NS(C)(=O)=O>>COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)cc(NS(C)(=O)=O)c4OC)c4ccccc34)n2)cc(OC)c1,,CC(=O)OC(C)C,,CCN(CC)CC,,test
US20120129806A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(C(F)(F)F)cc1)C(=O)N1C[C@H](CCCB2OC(C)(C)C(C)(C)O2)[C@](N=[N+]=[N-])(C(=O)OCC(=O)c2ccccc2)C1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(C(F)(F)F)cc1)C(=O)N1C[C@H](CCCB2OC(C)(C)C(C)(C)O2)[C@](N)(C(=O)O)C1,[Zn],CC(=O)O,,,,test
US20130096133A1,CCOC(=O)CN1CCN(Cc2ccc(OC(F)(F)F)cc2)CC1.NN>>NNC(=O)CN1CCN(Cc2ccc(OC(F)(F)F)cc2)CC1,,CCO,,,,test
US20100324041A1,C1CNCCN1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=S(=O)(c1ccccc1)n1ccc2c(Cl)c(-c3cccc(F)c3)cnc21>>CC(C)(C)OC(=O)N1CCN(c2c(-c3cccc(F)c3)cnc3c2ccn3S(=O)(=O)c2ccccc2)CC1,,CN1CCCC1=O,ClCCl,O,,test
US20040116471A1,CCOC(=O)Cl.c1ccc2c(C3CCNCC3)c[nH]c2c1>>CCOC(=O)N1CCC(c2c[nH]c3ccccc23)CC1,,ClCCl,,O,,test
US20140206681A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COc1cc(C(=O)Nc2cc(C(F)(F)F)ccn2)c(F)cc1Br>>COc1cc(C(=O)Nc2cc(C(F)(F)F)ccn2)c(F)cc1B1OC(C)(C)C(C)(C)O1,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20110071084A1,CC(=O)N1CCNCC1.Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(OC(=O)CCCCl)c3cc(Cl)ccc32)c(C)c1>>CC(=O)N1CCN(CCCC(=O)OC2CCCN(C(=O)c3ccc(NC(=O)c4ccccc4C)cc3C)c3ccc(Cl)cc32)CC1,,CC#N,O,[I-].[Na+],,test
US20150065705A1,Cc1ccc(S(=O)(=O)OCn2cnc(N3CCN(c4ccc(F)cc4)CC3)nc2=O)cc1.c1ccc2[nH]ncc2c1>>O=c1nc(N2CCN(c3ccc(F)cc3)CC2)ncn1Cn1cc2ccccc2n1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US04432984,ClCC1COc2ccccc2O1.O=[N+]([O-])O>>O=[N+]([O-])c1ccc2c(c1)OC(CCl)CO2,,CC(=O)O,O,,,test
US20130225588A1,COC(=O)Cc1cc2ccc(Cl)cc2c(-c2ccc(S(=O)(=O)c3ccc(F)cc3F)cc2)c1C>>Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)c2ccc(F)cc2F)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US05312617,CCCCCCCCCCN.OCC1CO1>>CCCCCCCCCCNCC(O)CO,,CO,,,,test
US04845122,O=C(CBr)CC(=O)Nc1ccccc1.O=C=Nc1ccccc1>>O=C1COC(Nc2ccccc2)=C1C(=O)Nc1ccccc1,,C1COCCO1,,O,[H-].[Na+],test
US20130123268A1,OC1(c2cnccn2)CC2CCC(C1)N2Cc1ccccc1>>OC1(c2cnccn2)CC2CCC(C1)N2,[Pd],O,,O=C[O-].[NH4+],,test
US20080096877A1,CN(c1cccc2cc(C(=O)NCC3(O)CCN(Cc4ccccc4)CC3)[nH]c12)S(=O)(=O)c1cccs1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CN(c1cccc2cc(C3=NCC4(CCN(Cc5ccccc5)CC4)S3)[nH]c12)S(=O)(=O)c1cccs1,,C1CCOC1,,Cc1ccccc1,,test
US20090233918A1,Cl.Cn1c(N2CCC(c3ccccc3)C2)nc(-c2ccncc2)cc1=O>>Cl.Cn1c(N2CCC(c3ccccc3)C2)nc(-c2ccncc2)cc1=O,,CCOC(C)=O,CO,,,test
US20050261337A1,CC(C)[Mg]Cl.O=Cc1nc2cc(Cl)ccc2cc1Cc1ccccc1>>CC(C)C(O)c1nc2cc(Cl)ccc2cc1Cc1ccccc1,,ClCCl,,,,test
US20040132727A1,COc1cc2nccc(Oc3ccc(NC(=O)COc4ccc(Cl)cc4Cl)cc3)c2cc1OC>>COc1cc2nccc(Oc3ccc(NCCOc4ccc(Cl)cc4Cl)cc3)c2cc1OC,,C1CCOC1,,Cl,[Na+].[OH-],test
US03975537,COC(=O)c1ccc(O)c(Cl)c1.COS(=O)(=O)OC>>COC(=O)c1ccc(OC)c(Cl)c1,,CCOCC,,O,[Na+].[OH-],test
US20030147844A1,CC(C)(C)OC(=O)NCCC(=O)O.O=S(=O)(CCl)OCl>>CC(C)(C)OC(=O)NCCC(=O)CCl,,O,,O=C([O-])O.[Na+],,test
US20010039344A1,COC(=O)C(CC1CCCC1)c1ccc(F)c(C(F)(F)F)c1.C[S-]>>COC(=O)C(CC1CCCC1)c1ccc(SC)c(C(F)(F)F)c1,,CN(C)C=O,,Cl,,test
US20100029650A1,CC(C)OC(=O)Cl.CS(=O)(=O)c1ccc(-c2ccc(OCC3CCNCC3)cc2)c(F)c1>>CC(C)OC(=O)N1CCC(COc2ccc(-c3ccc(S(C)(=O)=O)cc3F)cc2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20060058264A1,COC(=O)[C@@H]1C[C@H](N)C(=O)[C@@H]2[C@@]3(C)C[C@@H](c4ccoc4)OC(=O)[C@@H]3CC[C@]21C.O=S(=O)(Cl)c1ccccc1>>COC(=O)[C@@H]1C[C@H](NS(=O)(=O)c2ccccc2)C(=O)[C@@H]2[C@@]3(C)C[C@@H](c4ccoc4)OC(=O)[C@@H]3CC[C@]21C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CO,test
US20030092694A1,CCC1CN(Cc2ccccc2)CCN1c1nccnc1Cl.ClCCl>>CCC1CNCCN1c1nccnc1Cl.Cl,,ClCCl,,CC(Cl)OC(=O)Cl,,test
US20060235033A1,CC(N)c1ccc(F)c(F)c1.COc1cc2c(Oc3ccc(N)c(F)c3)ccnc2cc1OCCCN1CCOCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2c(Oc3ccc(NC(=O)NC(C)c4ccc(F)c(F)c4)c(F)c3)ccnc2cc1OCCCN1CCOCC1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20140066369A1,CCOC(=O)C1CCC(N2CCN(C(=O)OC(C)(C)C)CC2)C(F)C1>>CC(C)(C)OC(=O)N1CCN(C2CCC(CO)CC2F)CC1,,C1CCOC1,,[BH4-].[Li+],,test
US20090118501A1,C1CCC(NC2CCCC2)C1.Nc1nccs1.O=C(n1ccnc1)n1ccnc1>>O=C(Nc1nccs1)N(C1CCCC1)C1CCCC1,,CCOC(C)=O,ClCCl,CN(C)c1ccccn1,,test
US20060004043A1,CC(O)C1CCCC1.Oc1ccc2cc(Br)ccc2c1>>Brc1ccc2cc(OCCC3CCCC3)ccc2c1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04663339,CC(=O)Nc1c(Cl)cccc1NCc1ccc(Sc2ccc(C)cc2)cc1>>Cc1ccc(Sc2ccc(Cn3c(C)nc4c(Cl)cccc43)cc2)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05932601,BrCc1ccccc1.CCOC(=O)CCCCc1ccc(O)c(OC)c1>>CCOC(=O)CCCCc1ccc(OCc2ccccc2)c(OC)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050153987A1,CCOC(=O)c1ccc(Cl)nc1.N#Cc1ccc2c(c1)CC(=O)N2>>CCOC(=O)c1ccc(-c2c(O)[nH]c3ccc(C#N)cc23)nc1,,CN(C)C=O,O,[H-].[Na+],[Cl-].[NH4+],test
US20070191603A1,COC(=O)c1ccc(O)c(Cl)c1.O=[N+]([O-])O>>COC(=O)c1cc(Cl)c(O)c([N+](=O)[O-])c1,,CCOCC,,,,test
US20070225267A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1C[C@H](CCC2CCCCC2)OC[C@@H]1[C@@H](O)[C@@H](N)Cc1ccccc1>>CC(=O)N[C@@H](Cc1ccccc1)[C@H](O)[C@H]1CO[C@@H](CCC2CCCCC2)CN1C(=O)OC(C)(C)C,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US05648490,Nc1nc(N)c(N=O)c(N)n1.O.O=CO>>Nc1nc(N)c(NC=O)c(N)n1.O,[Pd],O,,O=C[O-].[NH4+],,test
US05912246,CCOc1ccc2nc(CCl)cn2c1.Clc1ccc(N2CCNCC2)c(Cl)c1>>CCOc1ccc2nc(CN3CCN(c4ccc(Cl)cc4Cl)CC3)cn2c1,,C1CCOC1,,CCN(CC)CC,,test
US20160122345A1,CC[C@@H]1NCc2cc(C(=O)N[C@@H](CO)c3ccc(S(=O)(=O)CC)cc3)cnc21.CO.O=C[C@@H]1CC[C@@H](C(F)(F)F)CC1>>CC[C@H]1c2ncc(C(=O)N[C@@H](COC)c3ccc(S(=O)(=O)CC)cc3)cc2CN1C[C@@H]1CC[C@@H](C(F)(F)F)CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US08114866B2,CCOC(=O)COC(=O)N1CCN(c2ccc(-c3cccc(C(F)(F)F)c3)nn2)CC1.CN>>CNC(=O)COC(=O)N1CCN(c2ccc(-c3cccc(C(F)(F)F)c3)nn2)CC1,,C1CCOC1,,,,test
US04036979,NO.O=C=NC1CCCc2sccc21>>O=C(NO)NC1CCCc2sccc21,,CCN(CC)CC,,Cl,,test
US03953456,ClCC1CO1.O=c1ccc2c(O)cccc2[nH]1>>O=c1ccc2c(OCC3CO3)cccc2[nH]1,,O,,[Na+].[OH-],,test
US20150158818A1,CCOC(=O)C(=O)Cl.CN(C)c1ccncc1.CN(N)C(=O)OC(C)(C)C>>CCOC(=O)/C=C/N(C)C,CN(C)c1ccncc1,CC1CCCO1,,CCN(CC)CC,,test
US20100160302A1,CC1(C23CC4CC2CC(CN2CCCS2(=O)=O)(C4)C3)OCCO1>>CC(=O)C12CC3CC1CC(CN1CCCS1(=O)=O)(C3)C2,,CC(C)=O,CCOC(C)=O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120177748A1,CC(C)S(=O)(=O)c1ccc(-c2cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(-c3cc(-c4ccc(CN(C)C(=O)OC(C)(C)C)cc4F)no3)c2)nc1>>CNCc1ccc(-c2cc(-c3cc(-c4ccc(S(=O)(=O)C(C)C)cn4)cnc3N)on2)c(F)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120277224A1,CC(=O)n1nc(C)c2cc(C(=O)O)ccc21.CC1(C)OC(=O)CC(=O)O1>>CC(=O)n1nc(C)c2cc(C(=O)C3C(=O)OC(C)(C)OC3=O)ccc21,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20070043013A1,CC(C)(C)OC(=O)NC1(CC(=O)N2CC(Oc3ccc(Cl)cc3)C2)CCC1>>CC(C)(C)OC(=O)NC1(CCN2CC(Oc3ccc(Cl)cc3)C2)CCC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140199263A1,COc1ncc(Br)cc1C(=O)O.Nc1c(O)cccc1F>>COc1ncc(Br)cc1C(=O)Nc1c(O)cccc1F,,ClCCl,O=S(Cl)Cl,CCN(CC)CC,O,test
US20130089512A1,CCN(C(C)C)C(C)C.NC1CCOCC1.O=[N+]([O-])c1c(Cl)cc(Cl)nc1Cl>>O=[N+]([O-])c1c(Cl)nc(Cl)nc1NC1CCOCC1,,ClCCl,,Cl,O,test
US04491580,O=C1C[C@@H](CO)N1.O=S(=O)(Cl)c1ccccc1>>O=C1C[C@@H](COS(=O)(=O)c2ccccc2)N1,,ClCCl,,CCN(CC)CC,,test
US20060079687A1,CCCN.O=Cc1cc(S(=O)c2cccc(NS(=O)(=O)c3ccccc3)c2)ccc1[N+](=O)[O-]>>CCCNCc1cc(S(=O)c2cccc(NS(=O)(=O)c3ccccc3)c2)ccc1[N+](=O)[O-],,ClCCCl,,O=C([O-])O.[Na+],,test
US20040077726A1,NO.O=C(Cl)C=Cc1cccc(NS(=O)(=O)/C=C/c2ccccc2)c1>>O=C(C=Cc1cccc(NS(=O)(=O)/C=C/c2ccccc2)c1)NO,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20100056511A1,CC(=O)Cl.CC(C)C(=O)CNC(C)(C)c1cccc([N+](=O)[O-])c1>>CC(=O)N(CC(=O)C(C)C)C(C)(C)c1cccc([N+](=O)[O-])c1,,ClCCl,,CCN(CC)CC,,test
US20070225288A1,CCOC(=O)C1=C(c2ccccc2)c2ccc(OC)cc2C1Br.NC1CCCCC1>>CCOC(=O)C1=C(c2ccccc2)c2ccc(OC)cc2C1NC1CCCCC1,,C1CCOC1,,,,test
US20140107093A1,NO.O=Cc1ccc(I)cc1>>ON=Cc1ccc(I)cc1,,CCO,,,,test
US20090312381A1,C=CCn1c(-c2ccc(Cl)cc2)n[nH]c1=O.COC(=O)CCl>>C=CCn1c(-c2ccc(Cl)cc2)nn(CC(=O)OC)c1=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20050020652A1,CCCCOC(C)(Cc1ccc(OCCC2CN(Cc3ccc(OC)cc3)C(=O)N2C)cc1)C(=O)OCC>>CCCCOC(C)(Cc1ccc(OCCC2CNC(=O)N2C)cc1)C(=O)OCC,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20150152050A1,CCOC(=O)C(N=[N+]=[N-])[C@@H](C)C(F)(F)F>>CCOC(=O)[C@@H](N)[C@@H](C)C(F)(F)F,[Pd],CCO,,[H][H],,test
US20100087449A1,CCOC(=O)CC(=O)c1ccncn1.N=C(N)CCNC(=O)OCc1ccccc1>>O=C(NCCc1nc(-c2ccncn2)cc(=O)[nH]1)OCc1ccccc1,,CCO,,Cl,[Na+].[OH-],test
US20140005222A1,COC(=O)c1ccc(C)c(NC(=O)c2cc(N3CCC(O[Si](C)(C)C(C)(C)C)CC3)nc3ccccc23)c1C>>COC(=O)c1ccc(C)c(NC(=O)c2cc(N3CCC(O)CC3)nc3ccccc23)c1C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150225427A1,C#Cc1cc(Nc2nccc(Oc3ccc(N)c4ccccc34)n2)cc(C(=O)NCCN2CCOCC2)c1.Cc1ccc(-n2nc([Si](C)(C)C)cc2C(=O)O)cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>C#Cc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc([Si](C)(C)C)nn4-c4ccc(C)cc4)c4ccccc34)n2)cc(C(=O)NCCN2CCOCC2)c1,,CN(C)C=O,O,CCN(CC)CC,,test
US20080176862A1,CN1C(=O)C(c2ccc(OS(=O)(=O)C(F)(F)F)cc2)(c2ccc(F)c(Br)c2)N=C1N.OB(O)c1cncc(Cl)c1>>CN1C(=O)C(c2ccc(OS(=O)(=O)C(F)(F)F)cc2)(c2ccc(F)c(-c3cncc(Cl)c3)c2)N=C1N,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US04230710,COc1cc2c(cc1OC)C1CC(Nc3ccc(NC(C)=O)cc3)CCN1CC2.O=C(O)/C=C/C(=O)O>>COc1cc2c(cc1OC)C1CC(Nc3ccc(NC(C)=O)cc3)CCN1CC2.O=C(O)/C=C/C(=O)O,,CCO,,Cl,,test
US20160075711A1,CCCC[Sn](CCCC)(CCCC)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.O=Cc1c(Br)ccnc1F>>O=Cc1c(-c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)ccnc1F,,CC#N,O,,,test
US06235740B1,Cc1cccc(N)c1C.O=C1CCC(=O)N1Cl>>Cc1ccc(Cl)c(N)c1C,,CN(C)C=O,,,,test
US20110136763A1,CCOC(=O)CC1OB(O)c2cc(Oc3cnccn3)cc(C)c21>>Cc1cc(Oc2cnccn2)cc2c1C(CC(=O)O)OB2O,,CO,O,Cl,[Li+].[OH-],test
US20130203745A1,Brc1ccc(C2CN(Cc3ccccc3)CCO2)cc1.Cc1cccc(C)c1C=O>>Cc1cccc(C)c1C(O)c1ccc(C2CN(Cc3ccccc3)CCO2)cc1,,C1CCOC1,,[Li]C(C)(C)C,,test
US20160060267A1,Br[Mg]C1CC1.CC=C(C(=O)OCC)C(=O)c1ccccc1>>CCOC(=O)C(C(=O)c1ccccc1)C(C)C1CC1,Cl[Cu],C1CCOC1,,,,test
US20050038260A1,NC(=O)[C@@H](NCc1ccccc1)[C@@H]1CSC(=O)N1Cc1ccccc1>>O=C1SC[C@H]2[C@@H]1N(Cc1ccccc1)C(=O)N2Cc1ccccc1,,CN(C)C=O,,CCOC(C)=O,Cl,test
US04764514,COc1ccc(C(=O)Cl)cc1.O=C1CSCN1>>COc1ccc(C(=O)N2CSCC2=O)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20100137318A1,CCC(CC)c1c[nH]c(C)c1.CN.O=C(Cl)C(Cl)(Cl)Cl>>CCC(CC)c1cc(C)[nH]c1C(=O)NC,,O,,C1CCOC1,,test
US20100286152A1,CN(C)C=O.CN1CCN(C(C(=O)O)c2ccc3c(c2)OCO3)CC1.CO>>COC(=O)C(=O)C(c1ccc2c(c1)OCO2)N1CCN(C)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20070238726A1,Cn1c(NCC2CC2)ncc(-c2ccc(OCc3ccccc3)c(F)c2)c1=O>>Cn1c(NCC2CC2)ncc(-c2ccc(O)c(F)c2)c1=O,,O=C(O)C(F)(F)F,,,,test
US20080312270A1,COC(=O)Cc1ccc(Oc2ccc3c(cnn3COCC[Si](C)(C)C)c2[N+](=O)[O-])c(OC)c1>>COC(=O)Cc1ccc(Oc2ccc3c(cnn3COCC[Si](C)(C)C)c2N)c(OC)c1,[Pd],,,,,test
US20140163001A1,CC(C)(C)n1ncc(-c2nc(CNC(=O)O)cs2)c1-c1ccc(F)cc1>>CC(C)(C)n1ncc(-c2nc(CN)cs2)c1-c1ccc(F)cc1,,O=C(O)C(F)(F)F,,,,test
US20090143372A1,CCOC(=O)Cl.CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4csc(CNC)c4)cc23)CC1>>CCOC(=O)N(C)Cc1cc(-c2cc(C(N)=O)c3[nH]cc(C4CCN(S(=O)(=O)CC)CC4)c3c2)cs1,,CN(C)C=O,,CCN(CC)CC,,test
US06114325,CCCCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCCN(C)C.Cl>>CCCCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCCN(C)C.Cl,,CCOC(C)=O,,,,test
US20140288045A1,CCOC(=O)CBr.CCc1cc(Cl)c(Cl)cc1N>>CCOC(=O)CNc1cc(Cl)c(Cl)cc1CC,,CN(C)C=O,,[H-].[Na+],,test
US20040204586A1,BrCc1ccccc1.O=c1[nH]c2ccc(Cl)cc2c(=O)o1>>O=c1oc(=O)n(Cc2ccccc2)c2ccc(Cl)cc12,,CN(C)C=O,,[H-].[Na+],,test
US04255573,Nc1ncccn1.O=C(CBr)c1ccccc1>>c1ccc(-c2cn3cccnc3n2)cc1,,CCO,,,,test
US20090281149A1,CN(C)C(=O)CCC#Cc1cccc(C(O)CCNC(=O)C(F)(F)F)c1>>CN(C)C(=O)CCCCc1cccc(C(O)CCNC(=O)C(F)(F)F)c1,,CCO,,,,test
US20130184241A1,N#CCc1ccccc1.O=Cc1ccc([N+](=O)[O-])cc1>>N#CC(=Cc1ccc([N+](=O)[O-])cc1)c1ccccc1,,CCO,,C,C[O-].[Na+],test
US20040138273A1,CNCCNc1ccc([N+](=O)[O-])c(N)n1.O=[N+]([O-])c1ccc(F)cc1-c1ccc(Cl)cc1Cl>>CN(CCNc1ccc([N+](=O)[O-])c(N)n1)c1ccc([N+](=O)[O-])c(-c2ccc(Cl)cc2Cl)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US04105673,CCCCCCC(O)CCCCCCCCCCC(=O)O>>CCCCCCC1(O)CCCCCCCCCCC(=O)O1,,CC#N,,CCN(CC)CC,C[n+]1ccccc1Cl.[I-],test
US05773442,CC(C)(C)OC(=O)NCC(=O)O.N#Cc1ccc(N)cc1>>CC(C)(C)OC(=O)NCC(=O)Nc1ccc(C#N)cc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20100056587A1,CCI.COC(=O)C1CCC(C(C)C)CC1>>CCC1(C(=O)OC)CCC(C(C)C)CC1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20080292588A1,COC(=O)[C@@H]1[C@H]2CC[C@H](O2)[C@@H]1NC(=O)OCc1ccccc1>>COC(=O)[C@@H]1[C@H]2CC[C@H](O2)[C@@H]1N,[Pd],CCOC(C)=O,,,,test
US20110092474A1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.Clc1cnnc(Cl)c1>>CC(C)(C)OC(=O)N[C@@H]1CCN(c2cnnc(Cl)c2)C1,,C1CCOC1,,CCN(CC)CC,,test
US20070149564A1,[N-]=[N+]=NCC1(c2onc(-c3ccc(O)cc3)c2-c2ccccc2)CC1>>NCC1(c2onc(-c3ccc(O)cc3)c2-c2ccccc2)CC1,[Pd],CO,,,,test
US04623650,O=[N+]([O-])c1ccc(F)c(-c2ccccc2)c1>>Nc1ccc(F)c(-c2ccccc2)c1,,O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US04772600,CN(C)CCN.C[C@@H](C(=O)O)n1c(-c2ccc(Cl)cc2)nc2cccnc21>>C[C@@H](C(=O)NCCN(C)C)n1c(-c2ccc(Cl)cc2)nc2cccnc21,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20150045384A1,CN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@H]3[C@H]1C5.ClCc1ccccc1>>CN1CC[C@]23c4c5ccc(OCc6ccccc6)c4O[C@H]2C(=O)CC[C@H]3[C@H]1C5,,CN(C)C=O,,Cl,[H-].[Na+],test
US20150299188A1,COc1ccc(CNc2nccc(C(F)(F)F)c2C=O)cc1.Nc1cc2c(cc1Cl)CCC(c1ncccc1F)O2>>COc1ccc(CNc2nccc(C(F)(F)F)c2CNc2cc3c(cc2Cl)CCC(c2ncccc2F)O3)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20130331374A1,O=C1COC1.O=[N+]([O-])c1ccc(OC2CCNCC2)c(C(F)(F)F)c1>>O=[N+]([O-])c1ccc(OC2CCN(C3COC3)CC2)c(C(F)(F)F)c1,,ClCCCl,ClCCl,O=C([O-])O.[Na+],,test
US20140296231A1,Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1.N[C@H]1CCC[C@@H]1O>>N[C@H]1CCC[C@@H]1Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20030008867A1,O=Cc1cccc(-c2ccc(C(=O)N[C@H]3CN4CCC3CC4)s2)c1>>O=C(N[C@H]1CN2CCC1CC2)c1ccc(-c2cccc(CO)c2)s1,,CO,,[BH4-].[Na+],,test
US20160222005A1,CS(=O)(=O)Cl.c1ccc(COc2ccc(-c3nc4cc(C5CCNCC5)cnc4[nH]3)cc2)cc1>>CS(=O)(=O)N1CCC(c2cnc3[nH]c(-c4ccc(OCc5ccccc5)cc4)nc3c2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20130143892A1,N#Cc1ccc(F)c(F)c1.O=C(O)c1c[nH]cn1>>N#Cc1ccc(-n2cnc(C(=O)O)c2)c(F)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20140171429A1,COc1cc(C(=O)N2CCN(C)CC2)ccc1[N+](=O)[O-]>>COc1cc(C(=O)N2CCN(C)CC2)ccc1N,[Pd],CO,,,,test
US04923857,C=CCOC(=O)N1C[C@@H](O)C[C@H]1C=C(C)C(C)=O.CI>>C=CCOC(=O)N1C[C@@H](OC)C[C@H]1C=C(C)C(C)=O,O=[Ag],,,,,test
US20090131467A1,CC(C(=O)c1c(O)c2cccnc2n(-c2ccccc2)c1=O)c1ccccc1.NN>>CC(c1ccccc1)c1n[nH]c2c1c(=O)n(-c1ccccc1)c1ncccc21,,CN(C)C=O,,O,O,test
US20100292210A1,NC[C@H](O)c1ccccc1.O=Cc1ncc(Cl)nc1Cl>>O[C@@H](CNCc1ncc(Cl)nc1Cl)c1ccccc1,,ClCCCl,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20140275027A1,Clc1ccc(I)nc1Br.OB(O)c1ccccc1>>Clc1ccc(-c2ccccc2)nc1Br,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US06180627B2,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCc1cccc(CO)c1>>CN(Cc1cccc(CO)c1)C(=O)OC(C)(C)C,,C1CCOC1,O,,,test
US20070219181A1,CI.CN(C)C=O.O=C(O)C(O)c1ccc(F)cc1>>COC(=O)COCc1ccc(F)cc1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US04943591,CC(=O)CCCCOCCc1ccccc1.NCc1ccccc1>>CC(CCCCOCCc1ccccc1)NCc1ccccc1,O=[Pt],CCO,Cc1ccccc1,,,test
US05929097,COc1ccc(S(=O)(=O)N(C)c2c(C)cc(C#Cc3ccc(-c4ccccc4)cc3)cc2C(=O)O)cc1>>COc1ccc(S(=O)(=O)N(C)c2c(C)cc(CCc3ccc(-c4ccccc4)cc3)cc2C(=O)O)cc1,[Pd],CCOC(C)=O,CO,[H][H],,test
US20060025383A1,CS(=O)(=O)Cl.Cc1cc(C)c2oc(Nc3ccc(C4CN([C@@H]5CC[C@H](N6CCNCC6)CC5)c5ncnc(N)c54)cc3F)nc2c1>>Cc1cc(C)c2oc(Nc3ccc(-c4cn([C@@H]5CC[C@H](N6CCN(S(C)(=O)=O)CC6)CC5)c5ncnc(N)c45)cc3F)nc2c1,,ClCCl,,CCN(CC)CC,,test
US05451601,CC(C)(C)OC(=O)N1C[C@@H]2[C@H](F)CCC(c3ccccc3)(c3ccccc3)[C@@H]2C1.Cl>>Cl.F[C@@H]1CCC(c2ccccc2)(c2ccccc2)[C@@H]2CNC[C@H]12,,C1COCCO1,,,,test
US04284631,CC(C)(C)OC(=O)CON=C(C(=O)NC1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=CCS[C@H]12)c1csc(NC=O)n1>>O=CNc1nc(C(=NOCC(=O)O)C(=O)NC2C(=O)N3C(C(=O)OCc4ccc([N+](=O)[O-])cc4)=CCS[C@H]23)cs1,,COc1ccccc1,,O=C(O)C(F)(F)F,,test
US04273704,COC(=O)C12CC3CC(CC(N)(C3)C1C(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C2.Cl>>COC(=O)C12CC3CC(CC(N)(C3)C1C(=O)[C@@H](N)Cc1ccccc1)C2.Cl,,C1COCCO1,,,,test
US20090214675A1,C/C(N)=C/C#N.CCCOC(=O)CC(C)=O.Cc1cc(=O)c2cccc(C=O)c2o1>>CCCOC(=O)C1=C(C)NC(C)=C(C#N)C1c1cccc2c(=O)cc(C)oc12,,CC(C)O,,CC(=O)O,,test
US20160176861A1,O=C([O-])c1c(C(F)F)cccc1C(F)F>>OCc1c(C(F)F)cccc1C(F)F,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080039440A1,Nc1nccc(Oc2ccc3c(c2)CCCN3)n1.O=C=Nc1cccc(C(F)(F)F)c1>>Nc1nccc(Oc2ccc3c(c2)CCCN3C(=O)Nc2cccc(C(F)(F)F)c2)n1,,C1CCOC1,,,,test
US20060211734A1,CNc1cccc(OC2CCN(C)CC2)n1.O=C(Cl)c1c(F)cc(F)cc1F>>CN1CCC(Oc2cccc(N(C)C(=O)c3c(F)cc(F)cc3F)n2)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20160009677A1,COc1cc(C)c(Br)c(CBr)c1>>Cc1cc(O)cc(CBr)c1Br,,ClCCl,,BrB(Br)Br,CO,test
US20040152690A1,C[C@@H]1CN(c2ncc(CO)cc2Cl)CCN1.O=C(Nc1cc(C(F)(F)F)cc2nc(Cl)[nH]c12)c1cc(F)c(F)c(F)c1>>C[C@@H]1CN(c2ncc(CO)cc2Cl)CCN1c1nc2cc(C(F)(F)F)cc(NC(=O)c3cc(F)c(F)c(F)c3)c2[nH]1,,CCO,,,,test
US20150057238A1,CC(=O)OC(C)Cl.O=C([O-])[C@H]1C[C@@H]1C(=O)c1ccc(Cl)c(Cl)c1>>CC(=O)OC(C)OC(=O)[C@H]1C[C@@H]1C(=O)c1ccc(Cl)c(Cl)c1,,CN(C)C=O,,O,,test
US20150291527A1,CC(C)S.COC(=O)c1ccc(C)nc1Cl>>COC(=O)c1ccc(C)nc1SC(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070155721A1,CC1CCN(CCN2CCC(NC(=O)OC(C)(C)C)CC2)CC1.Cl.ClCCl>>CC1CCN(CCN2CCC(N)CC2)CC1.Cl.Cl.Cl,,C1COCCO1,,,,test
US20090203647A1,Nc1nc(OCc2ccc(F)cc2)ncc1F.O=C(Oc1ccccc1)Oc1ccccc1>>O=C(Nc1nc(OCc2ccc(F)cc2)ncc1F)Oc1ccccc1,,C1CCOC1,,CCOC(C)=O,[H-].[Na+],test
US04532349,O=[N+]([O-])c1ccc(Cl)cc1.Sc1ccc(Cl)cc1>>O=[N+]([O-])c1ccc(Sc2ccc(Cl)cc2)cc1,,CCO,,O,O=C([O-])[O-].[Na+].[Na+],test
US20040058894A1,CCCCCCCCI.O=Cc1cccc(O)c1>>CCCCCCCCOc1cccc(C=O)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05331007,CC(Cc1cccc([N+](=O)[O-])c1)(NC=O)c1ccccc1>>CC(Cc1cccc(N)c1)(NC=O)c1ccccc1,[Pd],CO,,,,test
US06617325B1,COC(=O)CC(C)(CCCBr)c1ccccc1.O=C(NC1CCNCC1)c1ccccc1-c1ccc(C(F)(F)F)cc1>>COC(=O)CC(C)(CCCN1CCC(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)CC1)c1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090137584A1,CC(C)(C)CC(=O)Nc1cc(Br)ccc1NCC1CC1>>CC(C)(C)Cc1nc2cc(Br)ccc2n1CC1CC1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20110190330A1,COC(=O)C1Cc2cnc(OCc3ccccc3)cc2C1=O>>O=C1CCc2cnc(OCc3ccccc3)cc21,,CS(C)=O,O,,,test
US20040006114A1,CCS(=O)(=O)N(Cc1cccnc1)c1cccc(CO)c1.Oc1ccccc1>>CCS(=O)(=O)N(Cc1cccnc1)c1cccc(COc2ccccc2)c1,,C1CCOC1,CCOC(C)=O,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130225558A1,C=CCC1(C)CN(C)Cc2c1[nH]c1ccc(C)cc21.c1cc(C2CO2)ccn1>>C=CCC1(C)CN(C)Cc2c1n(CC(O)c1ccncc1)c1ccc(C)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20120269804A1,CC(C)(C)OC(=O)Nc1cccc(Oc2cc(F)cc(Nc3ccc(I)cc3F)c2NS(=O)(=O)C2CC2)c1>>Nc1cccc(Oc2cc(F)cc(Nc3ccc(I)cc3F)c2NS(=O)(=O)C2CC2)c1,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US04230482,N#CC(C=CC(C#N)=C(O)C(=O)O)=C(O)C(=O)O.Nc1cccc(Cl)c1>>N#Cc1ccn(-c2cccc(Cl)c2)c1C(=O)O,,O,,Cc1ccccc1,,test
US20090023710A1,CC(=O)N1CCCCC1=O.Nc1ccccc1Sc1ncccn1>>CC(=O)N1CCC(Nc2ccccc2Sc2ncccn2)CC1,,ClCCCl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20040030134A1,Cc1ncc(C=CC(=O)CCCCc2ccc3c(n2)NCCC3)cn1.ClCCl>>OCCCc1ccccc1,,ClCCl,,,,test
US20100137278A1,CC(=O)Cl.Fc1nccnc1C1CCNCC1>>CC(=O)N1CCC(c2nccnc2F)CC1,,ClCCl,,CCN(CC)CC,,test
US20080113986A1,CN.Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1nc2cnc(Cl)nc2n(C)c1=O>>CNc1ncc2nc(-c3cc(NC(=O)c4cccc(C(F)(F)F)c4)ccc3C)c(=O)n(C)c2n1,,CS(C)=O,,C1CCOC1,,test
US20080234199A1,CCOC(=O)COc1ccc(C(CC)=C(c2ccc(O)cc2)c2ccc(O)cc2)cc1>>CCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(OCC(=O)O)cc1,,C1CCOC1,CCO,[Na+].[OH-],,test
US06433112B1,C[Si](C)(C)C1([Si](C)(C)C)C=CC=C1.ClP(c1ccccc1)c1ccccc1>>C[Si](C)(C)C1([Si](C)(C)C)C=CC=C1P(c1ccccc1)c1ccccc1,,CCOCC,,CCCCCC,[Li]CCCC,test
US20130274242A1,CS(=O)(=O)O.Cc1nn(-c2ccnc(Nc3ccc4c(c3)c(Cl)cn4C)n2)cc1CN1CC(O)C1>>Cc1nn(-c2ccnc(Nc3ccc4c(c3)c(Cl)cn4C)n2)cc1CN1CC(OS(C)(=O)=O)C1,,CO,,,,test
US20160264562A1,CCOC(=O)[C@@H](C)OC(=O)C1=C(C)NC(c2nccs2)=N[C@H]1c1ccc(Cl)cc1Cl.O=C1CCC(=O)N1Br>>CCOC(=O)[C@@H](C)OC(=O)C1=C(CBr)NC(c2nccs2)=N[C@H]1c1ccc(Cl)cc1Cl,,ClC(Cl)(Cl)Cl,,,,test
US20110065766A1,O=C(NC12CC3CC(C1)C(S)C(C3)C2)OCc1ccccc1>>NC12CC3CC(C1)C(S)C(C3)C2,,CCOCC,,Br,,test
US20060052413A1,O=C(CCCl)c1ccccc1.c1ccc(CCCC2CCNCC2)cc1>>O=C(CCN1CCC(CCCc2ccccc2)CC1)c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05041455,C=CCCOc1nsnc1-c1cccnc1.CI>>C=CCCOc1nsnc1-c1ccc[n+](C)c1.[I-],,CC(C)=O,,,,test
US20120225854A1,COC(=O)CNC(=O)[C@@H](N)COCc1ccccc1>>O=C1CNC(=O)C(COCc2ccccc2)N1,,CCN(CC)CC,CO,O=C(O)C(F)(F)F,,test
US20140315881A1,C=CC(=O)OC.Cc1ccc(C(NC(=O)Cc2ccc3oc(C(O)c4c(C)noc4C)cc3c2)c2ccccc2)c(C)c1>>COC(=O)CCOC(c1cc2cc(CC(=O)NC(c3ccccc3)c3ccc(C)cc3C)ccc2o1)c1c(C)noc1C,,C1CCOC1,O,[H-].[Na+],,test
US04853410,COc1cc2c(cc1OC)[C@@]13CC[NH+]4CC5=CCO[C@H]6CC(=O)N2[C@H]1[C@H]6[C@H]5C[C@H]43>>COc1cc2c(cc1OC)[C@@]13CCN4CC5=CCO[C@H]6CC(=O)N2[C@H]1[C@H]6[C@H]5C[C@H]43,,CC#N,,,,test
US20100010038A1,CCOC(=O)CCc1ccncc1C(=O)OC>>O=C1CCc2ccncc21,,C1CCOC1,,CO,[H-].[Na+],test
US20040180891A1,CCOc1cc(-c2cccc(C(=O)O)c2)nn1CCOc1ccc(-c2cc(C)cs2)cc1Cl.NCCN1CCOCC1>>CCOc1cc(-c2cccc(C(=O)NCN3CCOCC3)c2)nn1CCOc1ccc(-c2cc(C)cs2)cc1Cl,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US05122537,CC(=O)OC(C)=O.O=CN/C=C/c1c(O)ccc2ccccc12>>CC(=O)Oc1ccc2ccccc2c1/C=C/NC=O,,c1ccncc1,,,,test
US20100222398A1,COc1ccc(N=[N+]=[N-])cc1.N#CCc1ccc(Cl)cc1F>>COc1ccc(-n2nnc(-c3ccc(Cl)cc3F)c2N)cc1,,CCO,,C[O-].[Na+],,test
US20110212937A1,CNc1cc(C(=O)N(C)OC)nc(Cl)n1.O=C1CCC(=O)N1Br>>CNc1nc(Cl)nc(C(=O)N(C)OC)c1Br,,CC#N,,,,test
US20120077806A1,COCOC.O=C(CCCO)c1ccccc1>>CCCC(=O)c1ccc(OCOC)cc1,,ClCCl,,O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3,,test
US20100216794A1,CC(C)CBr.Oc1ccc(Br)nc1>>CC(C)COc1ccc(Br)nc1,,CN(C)C=O,,O,[H-].[Na+],test
US20110039843A1,Nc1cc(C(F)(F)F)cnc1O.O=C(Cl)c1ccncc1Cl>>O=C(Nc1cc(C(F)(F)F)cnc1O)c1ccncc1Cl,,O,,CCN(CC)CC,CN(C)C=O,test
US05166154,CCOC(=O)CN.O=C1Cc2ccccc2C1>>CCOC(=O)CNC1Cc2ccccc2C1,,CCO,,Cl,[BH3-]C#N.[Na+],test
US20100179126A1,CNC.COc1ncc(Br)cc1/C=C/C(=O)O>>COc1ncc(Br)cc1/C=C/C(=O)N(C)C,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20030208018A1,C=C(C)C(=O)OC.C=C(C)C(=O)OCCCO.C=C(C)C(=O)OCCS(=O)(=O)c1ccc(C)cc1>>C=C(C)C(=O)OC.C=C(C)C(=O)OCCCO.C=C(C)C(=O)OCCS(=O)(=O)c1ccc(C)cc1,,C1CCOC1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20150166480A1,COC(=O)c1ccc(B(O)O)cc1.FC1(CN2CCC(COc3ccc(Br)cc3)CC2)CCC1>>COC(=O)c1ccc(-c2ccc(OCC3CCN(CC4(F)CCC4)CC3)cc2)cc1,,O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US03998958,CN1CCCC1=N.O=C=Nc1cccc(Br)c1>>CN1CCCC1=NC(=O)Nc1cccc(Br)c1,,c1ccccc1,,,,test
US20060148805A1,CCCNCC1CC1.COc1ccc2nc(C(=O)C(C)(C)C)n(CC(=O)O)c2c1>>CCCN(CC1CC1)C(=O)Cn1c(C(=O)C(C)(C)C)nc2ccc(OC)cc21,,CN(C)C=O,ClCCCl,CCN(C(C)C)C(C)C,On1nnc2ccccc21,test
US20100069374A1,C#CC(C)(C)Oc1ccc([N+](=O)[O-])c(OCOC)c1>>COCOc1cc2c(cc1[N+](=O)[O-])C=CC(C)(C)O2,,Clc1ccccc1Cl,,,,test
US20150105369A1,Clc1nc2ccc(Br)cc2c(Cl)c1-c1ccccc1.Cn1cncc1C=O>>Cn1cncc1C(O)c1ccc2nc(Cl)c(-c3ccccc3)c(Cl)c2c1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US05658587,CC(C)(C)C(=O)Cl.COC(=O)c1cccc(C)c1O>>COC(=O)c1cccc(C)c1C(=O)C(C)(C)C,CN(C)c1ccncc1,ClCCl,,,,test
US04335048,CCCc1ccc(OCC(C)OC2CCCCO2)c2c(=O)cc(C(=O)O)oc12>>CCCc1ccc(OCC(C)O)c2c(=O)cc(C(=O)O)oc12,Cl,CCO,O,,,test
US05714487,COC(=O)Cc1ccc(OC[C@H]2C[C@H]3CN(c4ccc(Cl)cn4)CCN3C2)cc1>>OCCc1ccc(OC[C@H]2C[C@H]3CN(c4ccc(Cl)cn4)CCN3C2)cc1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100249123A1,COc1ccc(C(=O)Nc2ccc(C(C)(C)C#N)c(Br)c2)cc1OC.OB(O)c1ccccc1Cl>>COc1ccc(C(=O)Nc2ccc(C(C)(C)C#N)c(-c3ccccc3Cl)c2)cc1OC,,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20130231315A1,CC(C)(C(=O)Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.CNc1cnc(Cl)cc1-c1ccccc1C>>Cc1ccc(-c2cc(Cl)ncc2N(C)C(=O)C(C)(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1,CN(C)c1ccncc1,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US20100022535A1,COC(=O)CCCl.Cc1cccc(-c2[nH]c(Cc3ccc(F)c(O)c3)nc2-c2ccc3ncccc3c2)n1>>COC(=O)COc1cc(Cc2nc(-c3ccc4ncccc4c3)c(-c3cccc(C)n3)[nH]2)ccc1F,,CC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20040242494A1,CCCI.CC[C@@H](C(=O)OC(C)(C)C)n1cccc(NC(=O)OCc2ccccc2)c1=O>>CCCN(C(=O)OCc1ccccc1)c1cccn([C@@H](CC)C(=O)OC(C)(C)C)c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20090156804A1,O=C1CO[C@@H](c2ccc(F)cc2)CN1Cc1ccccc1>>Fc1ccc([C@H]2CN(Cc3ccccc3)CCO2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150111891A1,CB1OB(C)OB(C)O1.CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2c(Br)cccc2c1OS(C)(=O)=O>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2c(C)cccc2c1OS(C)(=O)=O,,CCO,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],,test
US20150203511A1,Cc1cc(C)n(-c2ccc(OCc3c(C)cccc3-n3nnn(C)c3=O)c(Cl)c2)n1.O=C1CCC(=O)N1Br>>Cc1cccc(-n2nnn(C)c2=O)c1COc1ccc(-n2nc(C)c(Br)c2C)cc1Cl,,O,,ClC(Cl)Cl,,test
US20050107364A1,CCCCC1(C)C(=O)C(C2=NS(=O)(=O)c3cc(NC(=O)OC(C)(C)C)ccc3N2)=C(O)c2ccccc21.Cl>>CCCCC1(C)C(=O)C(C2=NS(=O)(=O)c3cc(N)ccc3N2)=C(O)c2ccccc21.Cl,,C1COCCO1,,,,test
US05120843,CCNc1cccnc1N1CCN(CCCCCCOc2ccc(OC)cc2)CC1.O=C(O)/C=C/C(=O)O>>CCNc1cccnc1N1CCN(CCCCCCOc2ccc(OC)cc2)CC1.O=C(O)/C=C/C(=O)O,,CO,,CCOCC,,test
US20090099187A1,BrCCCCBr.COc1ccc(S(=O)(=O)Nc2ccc(Cl)c(Cl)c2)c2c1C[C@@H](N)CC2>>COc1ccc(S(=O)(=O)Nc2ccc(Cl)c(Cl)c2)c2c1C[C@@H](N1CCCC1)CC2,,CC#N,,CCN(C(C)C)C(C)C,,test
US04421758,Clc1ccc(OCC2CCC=CO2)c(Cl)c1.OC(CCl)CCc1ccc(Cl)cc1Cl>>ClCC(CCc1ccc(Cl)cc1Cl)O[C@H]1CCC[C@H](COc2ccc(Cl)cc2Cl)O1,CCN(CC)CC,CCOCC,,O=P(Cl)(Cl)Cl,,test
US20060264460A1,Cn1cc(Cl)c(C=O)n1.N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1>>Cn1cc(Cl)c(CNc2ccc3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)n1,,CCO,,[BH3-]C#N.[Na+],,test
US05217976,CCc1cc2c(cc(C(N)=O)c(=O)n2Cc2ccc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc2)c(CC)n1.Cl>>CCc1cc2c(cc(C(N)=O)c(=O)n2Cc2ccc(-c3ccccc3-c3nnn[nH]3)cc2)c(CC)n1.Cl,,CO,Cl,ClCCl,,test
US20150105391A1,CC(=O)Nc1cc(C)c(C(=O)CCl)c(C)c1.NC(N)=S>>CC(=O)Nc1cc(C)c(-c2csc(N)n2)c(C)c1,,Cc1ccccc1,,CCO,,test
US20140221344A1,CC(C)(C)OC(=O)N[C@H]1C[C@@H](F)CN(C(=O)OCc2ccccc2)C1>>CC(C)(C)OC(=O)N[C@@H]1CNC[C@H](F)C1,[Pd],CCO,,,,test
US04916152,O=S(=O)(Cl)c1ccc(Cl)cc1.O=S(=O)(NC1CCNC1)c1ccc(Cl)cc1>>O=S(=O)(NC1CCN(S(=O)(=O)c2ccc(Cl)cc2)C1)c1ccc(Cl)cc1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20100168240A1,COC(=O)c1ccc(CCC(/C=C/c2cc(F)ccc2O)CCc2ccc(C(=O)OC)cc2)cc1.FC(F)(F)c1ccc(CBr)cc1>>COC(=O)c1ccc(CCC(/C=C/c2cc(F)ccc2OCc2ccc(C(F)(F)F)cc2)CCc2ccc(C(=O)OC)cc2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140296261A1,Fc1ncccc1-c1ncnc2c1ncn2C1CCCCO1.Nc1c(Cl)ccc(NS(=O)(=O)CCCF)c1F>>O=S(=O)(CCCF)Nc1ccc(Cl)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20100197725A1,Cl.O=C(N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNC1(c2cccc(C(F)(F)F)c2)CC1)c1cccc2c1CCN(Cc1ccccc1)C2=O>>Cl.O=C(N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNC1(c2cccc(C(F)(F)F)c2)CC1)c1cccc2c1CCN(Cc1ccccc1)C2=O,,CCOCC,,,,test
US20070232583A1,CNC.Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)Cl)c3)n2)n1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)N(C)C)c3)n2)n1,,C1CCOC1,CCOC(C)=O,,,test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4cccnc4nn23)CC1.Cl>>Cl.O=c1cc(C2CCNCC2)n2nc3ncccc3c2[nH]1,,C1COCCO1,CO,,,test
US20050004167A1,NNC(=O)c1cccc2cccnc12.O=S(=O)(Cl)c1ccccc1>>O=C(NNS(=O)(=O)c1ccccc1)c1cccc2cccnc12,CN(C)c1ccncc1,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US06951882B2,COC(=O)c1ccccc1NC(=O)N[C@H]1COC(C)(C)O[C@H]1c1ccccc1>>CC1(C)OC[C@H](NC(=O)Nc2ccccc2C(=O)O)[C@H](c2ccccc2)O1,,C1CCOC1,,[Li+].[OH-],,test
US20160016960A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc(C(=O)NCC(=O)CCc3ccc(F)cc3)nn2c1N1CCC(C)(C)CC1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>Cc1nc2cc(-c3ncc(CCc4ccc(F)cc4)s3)nn2c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(=O)O,,Cc1ccccc1,,,,test
US05591762,CCc1nc2c(C)cc(-c3nc4cc(F)ccc4n3C)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCc1nc2c(C)cc(-c3nc4cc(F)ccc4n3C)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100093730A1,CCOC(=O)CN1CCCC(c2ccccc2)(c2ccccc2)C1=O>>O=C(O)CN1CCCC(c2ccccc2)(c2ccccc2)C1=O,,CCO,O,[Li+].[OH-],,test
US20030004340A1,CCCCCCN1CCC(C)(c2cccc(C#N)c2)C(C)C1.C[Si](C)(C)C=[N+]=[N-]>>CCCCCCN1CCC(C)(c2cccc(-c3nn[nH]c3[Si](C)(C)C)c2)C(C)C1,,C1CCOC1,,[Li]CCCC,,test
US20070179151A1,COc1ccc2c(c1)CC(=NO)C2=O.[OH-]>>COc1ccc(C(=O)O)c(CC#N)c1,,[Na+],[OH-],Cc1ccc(S(=O)(=O)Cl)cc1,,test
US06806230B1,CC(C)C(c1cncnc1C=NO)N(C)C(=O)Cc1ccccc1>>CC(C)C(c1cncnc1C#N)N(C)C(=O)Cc1ccccc1,,ClC(Cl)Cl,,,,test
US05846703,CCC1(c2ccccc2)C(=O)NCNC1=O.O=[N+]([O-])O>>O=c1nc([N+](=O)[O-])cc[nH]1,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20130252922A1,NC(=O)c1c(F)cncc1Nc1ccc(I)cc1F.O=c1[nH]c2cc(O)ccc2o1>>NC(=O)c1c(Nc2ccc(I)cc2F)cncc1Oc1ccc2oc(=O)[nH]c2c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110213157A1,CCOC(=O)CCCC1CCCCc2ccccc21>>O=C(O)CCCC1CCCCc2ccccc21,,CO,,Cl,[Na+].[OH-],test
US20010021718A1,CC(C)(C)OC(=O)C[C@@H](CCCC1CCCCC1)c1nc(C(=O)N2CCC(c3ccncc3)CC2)no1>>O=C(O)C[C@@H](CCCC1CCCCC1)c1nc(C(=O)N2CCC(c3ccncc3)CC2)no1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050197396A1,CCO.CCc1ccc(S(=O)(=O)O)cc1.C[C@H](N)C(=O)O>>CCOC(=O)[C@H](C)N.CCc1ccc(S(=O)(=O)O)cc1,,CCO,,,,test
US20090099184A1,O=C(NCc1ccc(Cl)cc1Cl)c1ccc(F)nc1.Oc1ccncc1>>O=C(NCc1ccc(Cl)cc1Cl)c1ccc(Oc2ccncc2)nc1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20100048502A1,C/C=C/C=O.CN(C)c1cccc(N)c1>>Cc1ccc2ccc(N(C)C)cc2n1,,Cc1ccccc1,,Cl,[Na+].[OH-],test
US20160009744A1,CC1(C)O[C@H]2[C@H](N)C[C@H](CO)[C@H]2O1.O=C(c1cc(Cc2cccc(Br)c2)cs1)c1cncnc1Cl>>CC1(C)O[C@H]2[C@H](Nc3ncncc3C(=O)c3cc(Cc4cccc(Br)c4)cs3)C[C@H](CO)[C@H]2O1,,CC(C)O,,CCN(C(C)C)C(C)C,Cl,test
US06716878B1,CC(C)(C)OC(=O)N[C@H](C(=O)c1ccc(N)cc1)C(C)(C)C.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@H](C(=O)c1ccc(NC(=O)OCc2ccccc2)cc1)C(C)(C)C,,ClCCl,,CCN(CC)CC,c1ccncc1,test
US20150191461A1,C=C(C)Cn1cc(-c2cc(C)cc(Nc3nccc(C(F)(F)F)n3)c2)cn1.C[N+]1([O-])CCOCC1.O=[Os](=O)(=O)=O>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnn(CC(C)(O)CO)c2)c1,O=[Os](=O)(=O)=O,,,C1CCOC1,O,test
US20120270838A1,BrCBr.Cc1cc(NC(=O)CO)ccc1Br>>Cc1cc(N2COCC2=O)ccc1Br,,CN(C)C=O,,[H-].[Na+],,test
US20140179743A1,CCOc1ccc(C=O)cc1.O=C1CSC(=S)N1>>CCOc1ccc(/C=C2\SC(=S)NC2=O)cc1,,CCO,,C1CCNCC1,,test
US20070049632A1,CC(C)(C)OC(=O)NN(C(=O)C1C(=O)[C@]2(C)CC[C@H]1C2(C)C)c1ccc(F)cc1Cl>>CC1(C)[C@@H]2CC[C@@]1(C)c1[nH]n(-c3ccc(F)cc3Cl)c(=O)c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US07790709B2,CN(C)C=O.c1cc2sccc2cn1>>CNCc1cc2cnccc2s1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US05204349,CC1(C)C2CC[C@@]1(CS(=O)(=O)N1CCC3(C=Cc4ccccc43)CC1)C(=O)C2.NO>>CC1(C)C2CC[C@@]1(CS(=O)(=O)N1CCC3(C=Cc4ccccc43)CC1)C(=NO)C2,,c1ccncc1,,Cl,O,test
US20130281428A1,CC(C)O.COc1ccc(-c2cnc(N)c(-c3ccc(NC(=O)c4cn(CC(F)(F)F)cc(-c5ccc(F)cc5)c4=O)cc3)c2)cc1OC.Cl>>COc1ccc(-c2cnc(N)c(-c3ccc(NC(=O)c4cn(CC(F)(F)F)cc(-c5ccc(F)cc5)c4=O)cc3)c2)cc1OC.Cl.O,,CC(C)O,,,,test
US20150080364A1,FC(F)(F)c1ccc(N2CCOCC2)c(CN2CCNCC2)c1.O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O>>O=C(ON1C(=O)CCC1=O)N1CCN(Cc2cc(C(F)(F)F)ccc2N2CCOCC2)CC1,,O,,CCN(C(C)C)C(C)C,ClCCl,test
US20070099956A1,Cc1cccc(C)c1/C=C/C1CCN(CC2OCCO2)C(=O)C1>>Cc1cccc(C)c1/C=C/C1CCN(CC=O)C(=O)C1,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20120302573A1,BrBr.CC(=O)c1nc(C)n(C(C)=O)c1C>>Cc1nc(C)n(C)c1C(=O)CBr,,O,,Br,O=C([O-])O.[Na+],test
US20110028501A1,COc1cccc(S(C)(=O)=O)c1>>CS(=O)(=O)c1cccc(O)c1,,Br,CC(=O)O,,,test
US20150284395A1,CCOC(CBr)OCC.NC(=O)c1cnn2c(=O)cc(-c3ccc4[nH]ncc4c3)[nH]c12>>O=c1cc(-c2ccc3[nH]ncc3c2)[nH]c2c(-c3ncco3)cnn12,,CN1CCCC1=O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20130053409A1,C=CC(=O)Cl.COc1cc(N2CC(N(C)C)C2)c(N)cc1Nc1ncc(C#N)c(-c2cnn3ccccc23)n1>>C=CC(=O)Nc1cc(Nc2ncc(C#N)c(-c3cnn4ccccc34)n2)c(OC)cc1N1CC(N(C)C)C1,,CO,ClCCl,,,test
US20150005279A1,CC(C)(C)OC(=O)N1CCCC(c2ccc(C(N)=O)c3[nH]ccc23)C1>>NC(=O)c1ccc(C2CCCNC2)c2cc[nH]c12,,CO,,CC(=O)Cl,,test
US20070027321A1,CCI.O=[N+]([O-])c1ncc(F)cc1O>>CCOc1cc(F)cnc1[N+](=O)[O-],,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090042851A1,CC(C)(C)OC(=O)N1CC[C@H](O)C1.COc1ccc(S(=O)(=O)Nc2ccc(Cl)cc2Cc2ccccn2)cc1OC>>COc1ccc(S(=O)(=O)N(c2ccc(Cl)cc2Cc2ccccn2)[C@@H]2CCN(C(=O)OC(C)(C)C)C2)cc1OC,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140088081A1,Cc1ccnc(Br)c1.Cc1ccnc(C2CN(C(=O)OC(C)(C)C)C2)c1>>CC(C)(C)OC(=O)N1CC(c2ccc3ccccc3n2)C1,[Pd],,,,,test
US20090093483A1,ClCCOCCCl.N#CCc1cccc(Cl)c1>>N#CC1(c2cccc(Cl)c2)CCOCC1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US06583150B1,COc1ccc(OC)c2c(Cl)ccnc12.[N-]=[N+]=[N-]>>COc1ccc(OC)c2c(N=[N+]=[N-])ccnc12,,CN(C)C=O,O,[Cl-].[NH4+],,test
US20110275611A1,BrCc1ccccc1.O=C1CCC(=O)N1>>O=C1CCC(=O)N1Cc1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04472192,CCOC=C=C(C#N)C(=O)OC.NNc1c(Cl)cc(Cl)cc1Cl>>COC(=O)c1cnn(-c2c(Cl)cc(Cl)cc2Cl)c1N,,CCCCO,,,,test
US05389680,O=C(Cl)CC(F)=C(F)F.O=[N+]([O-])c1ccc(O)cc1>>O=C(CC(F)=C(F)F)Oc1ccc([N+](=O)[O-])cc1,,CCOCC,,CCN(CC)CC,Cl,test
US20050054683A1,CC(=O)NC[C@H]1CN(c2cc(F)c(C3CCN(C(=O)COCc4ccccc4)CC3)c(F)c2)C(=O)O1>>CC(=O)NC[C@H]1CN(c2cc(F)c(C3CCN(C(=O)CO)CC3)c(F)c2)C(=O)O1,[Pd],CO,,,,test
US20070244120A1,CC(C)(C)OC(=O)n1nc(C(C)(C)C)cc1N.O=C=Nc1ccc(Cl)c(Cl)c1>>CC(C)(C)c1cc(NC(=O)Nc2ccc(Cl)c(Cl)c2)[nH]n1,,Cc1ccccc1,,,,test
US04011238,CC1(C)CN(CCCl)C1.O=C1NCCN1c1cccc(Cl)c1>>CC1(C)CN(CCN2CCN(c3cccc(Cl)c3)C2=O)C1,,CN(C)C=O,,[H-].[Na+],,test
US20060252768A1,CC(=O)OCc1ccc(C2=CCCN(C(=O)OC(C)(C)C)C2)cc1>>CC(C)(C)OC(=O)N1CCCC(c2ccc(CO)cc2)C1,[Pd],CCOC(C)=O,,,,test
US20030013875A1,CC1(c2cccc(N)c2)C2CN(CCCC3CCCCC3)CC21.CCS(=O)(=O)Cl>>CCS(=O)(=O)Nc1cccc(C2(C)C3CN(CCCC4CCCCC4)CC32)c1,,ClCCl,,c1ccncc1,,test
US20140057893A1,CC(C)(C)OC(=O)N1CCC([C@@H]2C[C@@H]2CCO)CC1.O=C(Cl)OCc1ccccc1>>O=C(OCc1ccccc1)N1CCC(C2CC2CCO)CC1,,C1COCCO1,,Cl,,test
US20080051418A1,CCCOc1cc(CCC(=O)OCC)[nH]n1.ClCc1ccc(Cl)cc1>>CCCOc1cc(CCC(=O)OCC)n(Cc2ccc(Cl)cc2)n1,,CN(C)C=O,,O,[H-].[Na+],test
US06103517,CC(=O)O.O=C(O)c1ccc(O)cc1>>CC(=O)Oc1ccc(C(=O)O)cc1,O=S(=O)(O)O,O,,,,test
US20160024110A1,CC(C)CO.COC(=O)CC(=O)CCl>>CC(C)COC(=O)CC(=O)CCl,CN(C)c1ccncc1,Cc1ccccc1,,,,test
US05344843,CCC(C)(C)C(=O)OCc1cccc(C)c1OCCOc1ccc([C@H](NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2)cc1>>CCC(C)(C)C(=O)OCc1cccc(C)c1OCCOc1ccc([C@H](N)C(=O)OCc2ccccc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US07074819B2,COc1ccc(C2(C)CSc3cc(OC)ccc3C2CCCCCCCCCNS(=O)(=O)CCCC(F)(F)C(F)(F)F)cc1>>CC1(c2ccc(O)cc2)CSc2cc(O)ccc2C1CCCCCCCCCNS(=O)(=O)CCCC(F)(F)C(F)(F)F,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20030028022A1,C1COCCN1.O=Cc1ccc(CN(Cc2nc3ccccc3[nH]2)C2CCCc3cccnc32)cc1>>c1cnc2c(c1)CCCC2N(Cc1ccc(CN2CCOCC2)cc1)Cc1nc2ccccc2[nH]1,,CO,,[BH3-]C#N.[Na+],,test
US05141945,CCc1c2n(c3ccccc13)C(=O)C(=Cc1ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c1C)CC2>>CCc1c2n(c3ccccc13)C(=O)C(Cc1nc[nH]c1C)CC2,[Pd],CC(=O)O,,O=C[O-].[NH4+],,test
US20140038941A1,BrBr.O=C(CCC1CCC(F)(F)CC1)C(F)(F)F>>O=C(C(Br)CC1CCC(F)(F)CC1)C(F)(F)F,,CN(C)C=O,,CCN(CC)CC,C[Si](C)(C)Cl,test
US20110118236A1,COC(=O)C(C)CCn1nc(C(F)(F)F)c2c1CCCC2>>CC(CCn1nc(C(F)(F)F)c2c1CCCC2)C(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20090082434A1,COc1ccccc1B(O)O.Fc1cccc(F)c1Br>>COc1ccccc1-c1c(F)cccc1F,Cc1ccccc1[P](c1ccccc1C)(c1ccccc1C)[Pd](Cl)(Cl)[P](c1ccccc1C)(c1ccccc1C)c1ccccc1C,,,O=C([O-])[O-].[K+].[K+],,test
US04329353,CI.O=C1CCC(C(=O)O)(c2ccc(F)cc2)CC1>>COC(=O)C1(c2ccc(F)cc2)CCC(=O)CC1,,CO,,[Na],C[O-].[Na+],test
US20150191478A1,CC(C)(C)c1ccc(-c2cncc3cc(-c4cncc(N)c4)oc23)cc1.O=C=Nc1ccccc1>>CC(C)(C)c1ccc(-c2cncc3cc(-c4cncc(NC(=O)Nc5ccccc5)c4)oc23)cc1,,C1CCOC1,,,,test
US20150274660A1,COc1cc(C2(C#N)CCC2)c([N+](=O)[O-])cc1O.ClCCCI>>COc1cc(C2(C#N)CCC2)c([N+](=O)[O-])cc1OCCCCl,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040171835A1,COCCl.Oc1cccc2ncccc12>>COCOc1cccc2ncccc12,,CN(C)C=O,O,[H-].[Na+],,test
US20110294807A1,CCC(C)c1ccc(N)cc1.COc1cccc2c(=O)oc(=O)[nH]c12>>CCC(C)c1ccc(NC(=O)c2cccc(OC)c2N)cc1,,CN(C)C=O,,,,test
US20060264484A1,O=C(CBr)c1ccccc1.O=C(O)c1ccc(S)cc1>>O=C(O)c1ccc(SCC(=O)c2ccccc2)cc1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20040127574A1,O=C1NC(Cc2ccc(F)cc2)C(c2ccc(F)cc2)O1>>NC(Cc1ccc(F)cc1)C(O)c1ccc(F)cc1,,CCO,,[Na+].[OH-],,test
US20160108059A1,CCN1CC2CC(OC)c3cc(=O)c(OC)c(n32)C1=O.O=C1CCC(=O)N1I>>CCN1CC2CC(OC)c3c(I)c(=O)c(OC)c(n32)C1=O,,ClCCl,,,,test
US20090192190A1,COC(=O)c1c(C)c(Br)cc(C(C)(C)C)c1OC.N#C[Cu]C#N>>COC(=O)c1c(C)c(C#N)cc(C(C)(C)C)c1OC,,CN(C)C=O,,,,test
US20100190981A1,CC(C)(C)C(=O)OCn1ccc2c(-c3cnn(/C(=C\C(N)=O)C4CCCC4)c3)ncnc21>>CC(C)(C)C(=O)OCn1ccc2c(-c3cnn([C@H](CC(N)=O)C4CCCC4)c3)ncnc21,,CO,,[H][H],,test
US20040024034A1,CCOC(=O)C(C)(C)Oc1ccc(SCCc2nc(-c3ccccc3)oc2C)cc1>>Cc1oc(-c2ccccc2)nc1CCSc1ccc(OC(C)(C)C(=O)O)cc1,,CCO,,Cl,[Na+].[OH-],test
US20110098296A1,CCOC(=O)c1cccc(N)c1.O=C(Cl)c1c(F)cccc1F>>CCOC(=O)c1cccc(NC(=O)c2c(F)cccc2F)c1,,ClCCl,,,,test
US05852016,COc1nc2cc(Cl)c(Cl)c(NS(C)(=O)=O)c2nc1OC.OCc1cccnc1>>COc1nc2cc(Cl)c(Cl)c(N(Cc3cccnc3)S(C)(=O)=O)c2nc1OC,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080242663A1,O=[N+]([O-])c1cc(OCc2ccccc2)cc(N2CCOCC2)c1>>Nc1cc(OCc2ccccc2)cc(N2CCOCC2)c1,O=[Pt]=O,CCOC(C)=O,,CCO,O=C([O-])[O-].[K+].[K+],test
US04978384,CCCc1c(C(=O)OCC)c(C(F)F)nc(C(F)(F)F)c1C(=O)OCC>>CCCc1c(C(=O)O)cnc(C(F)(F)F)c1C(=O)O,,CO,,[K+].[OH-],,test
US05716949,Br[Mg]C1CC1.O=c1c2ccccc2c2ccccc2c2ccccc12>>OC1(C2CC2)c2ccccc2-c2ccccc2-c2ccccc21,,C1CCOC1,,[Cl-].[NH4+],,test
US20120214802A1,Cc1csc(CN(C)C(=O)c2cccc(C(=O)N[C@@H](Cc3ccccc3)[C@H](O)[C@H]3C[C@@H](OCc4ccccc4)CN3C(=O)OC(C)(C)C)c2)n1>>Cc1csc(CN(C)C(=O)c2cccc(C(=O)N[C@@H](Cc3ccccc3)[C@H](O)[C@H]3C[C@@H](O)CN3)c2)n1,,ClCCl,,BrB(Br)Br,,test
US20160229804A1,Cc1ccc([N+](=O)[O-])c(Cl)n1.OB(O)c1ccccc1>>Cc1ccc([N+](=O)[O-])c(-c2ccccc2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05990336,O=C(O)/C=C/c1ccc(O)cc1.O=S(=O)(O)Cl>>O=C(O)/C=C/c1ccc(OS(=O)(=O)O)cc1,,c1ccncc1,,,,test
US20160068496A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CNC(=O)Nc1ccc(Br)cc1>>CNC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1,,Cc1ccccc1,,ClCCl,CC(=O)[O-].[K+],test
US20130005743A1,CC(=O)CC(C)=O.NC(N)=O>>Cc1cc(C)nc(O)n1,,CCO,,Cl,,test
US20120040954A1,C1CCNC1.COc1ccc2nc(-c3cc(C)c(OCCBr)c(C)c3)[nH]c(=O)c2c1>>COc1ccc2nc(-c3cc(C)c(OCCN4CCCC4)c(C)c3)[nH]c(=O)c2c1,,CN(C)C=O,,,,test
US20070072928A1,CN(CCC(O)c1ccccc1)C(=O)OC(C)(C)C.O=C1CCC(=O)N1Br>>CNCCC(Br)c1ccccc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090209607A1,Cn1ncc(Cl)c1-c1cc(C(=O)N[C@@H](Cc2ccccc2C(F)(F)F)CN2C(=O)c3ccccc3C2=O)oc1Cl>>Cn1ncc(Cl)c1-c1cc(C(=O)N[C@H](CN)Cc2ccccc2C(F)(F)F)oc1Cl,,C1CCOC1,CO,NN,,test
US20040102450A1,O=C(O)C(S)c1cccs1.O=C1CCC(=O)N1Cl>>O=C(O)C(S)c1ccc(Cl)s1,O=C(O)C(F)(F)F,ClCCl,,,,test
US20100240656A1,CCC(OS(=O)(=O)c1ccc(C)cc1)N(C(=O)OC(C)(C)C)C(C)C.NC(=O)c1nc[nH]c1N>>CC(C)N(CCCn1cnc(C(N)=O)c1N)C(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130102776A1,CC(C)(C)OC(=O)N1CCN(Cc2c(O)ccc3c2OCC3=O)CC1.Cc1ccc2c(C=O)c[nH]c2n1>>Cc1ccc2c(/C=C3\Oc4c(ccc(O)c4CN4CCN(C(=O)OC(C)(C)C)CC4)C3=O)c[nH]c2n1,C1CCNCC1,CO,,,,test
US20110034689A1,CC(C)(C)OC(=O)c1ccc(Oc2ccn3ncnc3c2)c(Cl)c1F>>O=C(O)c1ccc(Oc2ccn3ncnc3c2)c(Cl)c1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US06271225B1,O=C1Nc2ccc(F)cc2Oc2sc3c(c21)CCCC3>>O=C1Nc2ccc(F)cc2Oc2sc3ccccc3c21,,c1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20090075985A1,BrBr.COc1cccc(CN2C(=O)CC3(C)CCCC(C(C)=O)=C23)c1>>COc1cccc(CN2C(=O)CC3(C)CCCC(C(=O)CBr)=C23)c1,,C1COCCO1,ClC(Cl)Cl,,,test
US08129361B2,CC(C)(C)OC(=O)NC1(CCc2ccc(OCCCc3ccc4c(c3)CCO4)c(C(F)(F)F)c2)COC(C)(C)OC1.Cl>>Cl.NC(CO)(CO)CCc1ccc(OCCCc2ccc3c(c2)CCO3)c(C(F)(F)F)c1,,CCO,,,,test
US20120238574A1,NC1COC1.Nc1ccc(C(=O)C2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(Nc1ccc(C(=O)C2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1)NC1COC1,,C1CCOC1,,CCN(CC)CC,,test
US05521160,CO[C@H]1O[C@H](COS(=O)(=O)[O-])[C@@H](O[C@@H]2O[C@@H](C(=O)O)[C@@H](O[C@H]3O[C@H](COS(=O)(=O)[O-])[C@@H](O[C@@H]4O[C@H](C(=O)O)[C@@H](O[C@H]5O[C@H](COS(=O)(=O)[O-])[C@@H](O)[C@H](O)[C@H]5NS(=O)(=O)[O-])[C@H](O)[C@H]4O)[C@H](OS(=O)(=O)[O-])[C@H]3NS(=O)(=O)[O-])[C@H](O)[C@H]2OS(=O)(=O)[O-])[C@H](O)[C@H]1NS(=O)(=O)[O-].O=C(O)c1cccc(/C=C/c2ccccc2C(=O)O)c1.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]>>CO[C@H]1O[C@H](COS(=O)(=O)[O-])[C@@H](O[C@@H]2O[C@@H](C(=O)O)[C@@H](O[C@H]3O[C@H](COS(=O)(=O)[O-])[C@@H](O[C@@H]4O[C@H](C(=O)O)[C@@H](O[C@H]5O[C@H](COS(=O)(=O)[O-])[C@@H](O)[C@H](O)[C@H]5NS(=O)(=O)[O-])[C@H](O)[C@H]4O)[C@H](OS(=O)(=O)[O-])[C@H]3NS(=O)(=O)[O-])[C@H](O)[C@H]2OS(=O)(=O)[O-])[C@H](O)[C@H]1NS(=O)(=O)[O-].O=C(O)c1cccc(CCc2ccccc2C(=O)O)c1.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+],,O,,,,test
US20030001133A1,CC(C)CO.CCCCOP(=O)(Cl)OCCCC>>CCCCOP(=O)(OCCCC)OCC(C)C,,c1ccncc1,,ClCCl,,test
US06518268B1,O=C(OO)c1cccc(Cl)c1.O=C1NC(=O)C(=Cc2cc3ccccc3nc2Sc2ccc(Cl)cc2)S1>>O=C1NC(=O)C(=Cc2cc3ccccc3nc2S(=O)c2ccc(Cl)cc2)S1,,CO,ClCCl,,,test
US05192786,CN(C)C=O.ClCCCBr.Oc1ccc(Cc2ccccc2)cc1>>C.ClCCCOc1ccc(Cc2ccccc2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04550070,CC(=O)Cl.NNc1ccc([N+](=O)[O-])cc1>>CC(=O)NNc1ccc([N+](=O)[O-])cc1,,CC#N,,CCN(CC)CC,O,test
US20030078251A1,CCOC(=O)c1cc2cc(NC(=O)C[C@H]3O[C@H](c4cccc(OC)c4OC)c4cc(Cl)ccc4N(CC(C)(C)COC(C)=O)C3=O)ccc2[nH]1>>COc1cccc([C@H]2O[C@H](CC(=O)Nc3ccc4[nH]c(C(=O)O)cc4c3)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20080021023A1,C[Mg]Br.O=C(c1ccc(Br)c(F)c1)N1CCOCC1>>CC(=O)c1ccc(Br)c(F)c1,,C1CCOC1,,,,test
US05686482,COC(=O)c1ccc(OC(C)C)cc1OC>>COc1cc(OC(C)C)ccc1C(=O)O,,C1CCOC1,,Cl,[Na+].[OH-],test
US20060074119A1,Cc1ccccc1COc1cc(-n2cnc3ccccc32)sc1C(=O)O>>Cc1ccccc1COc1csc(-n2cnc3ccccc32)c1,,CC(=O)O,,CCOC(C)=O,,test
US20140323300A1,CC(C)(C)OC(=O)NNc1ccc(C(F)(F)F)cc1S(C)(=O)=O.O=C/C(Br)=C(/Br)C(=O)O>>CS(=O)(=O)c1cc(C(F)(F)F)ccc1N/N=C\C(Br)=C(\Br)C(=O)O,,Cl,,,,test
US20150119405A1,COc1cc(OC)c(Cl)c(-c2ccc3nc(N[C@@H]4C[C@@H](C(=O)N(C)C)C[C@@H]4NC(=O)OC(C)(C)C)ncc3c2)c1Cl>>COc1cc(OC)c(Cl)c(-c2ccc3nc(N[C@@H]4C[C@@H](C(=O)N(C)C)C[C@@H]4N)ncc3c2)c1Cl,,C1COCCO1,ClCCl,Cl,,test
US20010051631A1,C=O.CCc1cn2c(CNCCCCCNS(=O)(=O)C(F)(F)F)cccc2n1>>CCc1nc2cccc3n2c1CN(CCCCCNS(=O)(=O)C(F)(F)F)C3,,CC(=O)O,,,,test
US05658908,CC(C)(C)[Si](C)(C)Oc1ccccc1F.CCN(CC)C(=O)c1ccc(C=O)cc1.Oc1ccccc1F>>CCN(CC)C(=O)c1ccc(C(O)c2cc(O[Si](C)(C)C(C)(C)C)ccc2F)cc1,,CO,ClCCl,[Li]C(C)CC,,test
US20120258946A1,COC(=O)CC(=O)OC.O=[N+]([O-])c1ccc(F)cc1>>COC(=O)C(C(=O)OC)c1ccc([N+](=O)[O-])cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130165412A1,COC(=O)C1(N)CC1.O=C(O)c1nn(-c2ccc(F)cc2F)c2c1C[C@@H]1C[C@H]21>>O=C(NC1(CO)CC1)c1nn(-c2ccc(F)cc2F)c2c1C[C@@H]1C[C@H]21,,C1COCCO1,O,Cl,[BH4-].[Na+],test
US05639756,O=C(CBr)c1ccccc1.OCCCNc1nc2ccccc2[nH]1>>Br.O=C(Cn1c(NCCCO)nc2ccccc21)c1ccccc1,,CC(C)O,,,,test
US20150344423A1,COCOc1c(C)cc(-c2nc(C(=O)OC)nn2CC2CCCCC2)cc1C(C)(C)C>>COC(=O)c1nc(-c2cc(C)c(O)c(C(C)(C)C)c2)n(CC2CCCCC2)n1,,C1COCCO1,,Cl,,test
US06740650B2,COc1ccc(-c2ccc3cc(OC)c(OC)cc3c2)c([N+](=O)[O-])c1>>COc1ccc(-c2ccc3cc(OC)c(OC)cc3c2)c(N)c1,[Pd],CCOC(C)=O,,,,test
US20100261772A1,CC1(C)CC(=C(c2ccc(F)cc2)c2ccc(OS(=O)(=O)C(F)(F)F)cc2)CC(C)(C)C1.OB(O)c1ccoc1>>CC1(C)CC(=C(c2ccc(F)cc2)c2ccc(-c3ccco3)cc2)CC(C)(C)C1,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20070093521A1,CCOc1cc(C=O)cc(OCC)c1Cl.CCOc1cc(CN2CCC(Nc3nc4cc(OCCCOC)ccc4o3)CC2)cc(OCC)c1F>>CCOc1cc(CN2CCC(Nc3nc4cc(OCCCOC)ccc4o3)CC2)cc(OCC)c1Cl,,CC(=O)O,CCO,CCN(C(C)C)C(C)C,[BH3-]C#N.[Na+],test
US05955480,COc1ccc(B(O)O)cc1.Clc1ccc(-c2nc(-c3ccc(Br)cc3)c(-c3ccncc3)[nH]2)cc1>>COc1ccc(-c2ccc(-c3nc(-c4ccc(Cl)cc4)[nH]c3-c3ccncc3)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,[Na+].[OH-],,test
US20140288185A1,CCCCC12CCCC1(NC)C1CCC2C1.Cl>>CCCCC12CCCC1(NC)C1CCC2C1.Cl,,ClCCl,,,,test
US20070161673A1,CCNC(=O)c1cc(F)c(C)c(-c2cc(Cl)c(C(=O)c3ccc(F)cc3)cn2)c1.NN>>CCNC(=O)c1cc(F)c(C)c(-c2cc3[nH]nc(-c4ccc(F)cc4)c3cn2)c1,,C1CCOC1,,O,,test
US20120157425A1,CC#N.CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(O)cc3)CC2)cc1.CCOCCBr>>CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OC4CCOCC4)cc3)CC2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150315141A1,COc1ccc(CN2C(O)c3ccccc3S2(=O)=O)cc1.C[Si](C)(C)C#N>>COc1ccc(CN2C(C#N)c3ccccc3S2(=O)=O)cc1,,ClCCl,,CCOCC,FB(F)F,test
US20160229816A1,OCCc1cccc(-c2cccc(C(F)(F)F)c2)c1>>O=CCc1cccc(-c2cccc(C(F)(F)F)c2)c1,,CC#N,,,,test
US20110136780A1,CC(C)[C@H](C(=O)O)N1Cc2ccnc3[nH]cc(c23)C1=O.CC1(C#N)CNC1>>CC(C)[C@H](C(=O)N1CC(C)(C#N)C1)N1Cc2ccnc3[nH]cc(c23)C1=O,CN(C)c1ccncc1,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20040116429A1,CC(C)N.CSc1nc(Cl)c(-c2c(F)cccc2Cl)c(Cl)n1>>CSc1nc(Cl)c(-c2c(F)cccc2Cl)c(NC(C)C)n1,,ClCCl,,,,test
US20140315894A1,COc1ccc(C2=NN(C)C(=O)C2)cc1OC.N#CCC#N.O=Cc1ccccc1>>COc1ccc(-c2nn(C)c3c2C(c2ccccc2)C(C#N)=C(N)O3)cc1OC,,CCO,,CCN(CC)CC,,test
US04021457,COc1ccc(OC)cc1.O=C1OC(=O)c2ccccc21>>COc1ccc(OC)c(C(=O)c2ccccc2C(=O)O)c1,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20030207893A1,CN1CCNCC1.Cc1cccc2cc(C(=O)O)[nH]c12>>Cc1cccc2cc(C(=O)N3CCN(C)CC3)[nH]c12,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20040224997A1,CC(C)(CC(=O)c1ccc(-c2ccc(N)cc2)cc1)C(=O)O.N#CSCC(=O)c1ccc(Cl)cc1>>CC(C)(CC(=O)c1ccc(-c2ccc(Nc3nc(-c4ccc(Cl)cc4)cs3)cc2)cc1)C(=O)O,,CCCCO,,,,test
US20160052884A1,CCOC(=O)c1ccc(NC(=O)C(CCOC)n2cc(OC)c(-c3cc(Cl)ccc3C#N)cc2=O)cc1>>COCCC(C(=O)Nc1ccc(C(=O)O)cc1)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O,,CO,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05411980,CCCCc1nn(C(C(=O)OC)c2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCCc1nn(C(C(=O)OC)c2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,CC(=O)O,,,,test
US20040132727A1,COc1cc2nccc(Oc3ccc(NC(=O)COc4c(Cl)cccc4Cl)cc3)c2cc1OC>>COc1cc2nccc(Oc3ccc(NCCOc4c(Cl)cccc4Cl)cc3)c2cc1OC,,C1CCOC1,,Cl,[Na+].[OH-],test
US04654343,CC(=O)Cl.Cc1nnc2ccc(-c3cccc(NC(C)C)c3)nn12>>Cc1nnc2ccc(-c3cccc(CC(=O)NC(C)C)c3)nn12,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20140336177A1,Cc1c(C(O)CN2CCN(C(=O)OC(C)(C)C)C[C@H]2CO)cccc1[N+](=O)[O-]>>Cc1c(C2CN3CCN(C(=O)OC(C)(C)C)C[C@H]3CO2)cccc1[N+](=O)[O-],,c1ccccc1,,CCCCP(=CC#N)(CCCC)CCCC,,test
US20120046269A1,[N-]=[N+]=NC[C@@H](Nc1ncnc2c(C(N)=O)cccc12)c1ccccc1>>NC[C@@H](Nc1ncnc2c(C(N)=O)cccc12)c1ccccc1,[Pd],CCO,,ClC(Cl)Cl,,test
US05804097,Cc1ccc(C(=O)Oc2ccc(OCc3ccccc3)cc2)cc1>>Cc1ccc(C(=O)Oc2ccc(O)cc2)cc1,[Ni],CCO,,,,test
US05055464,CCOC(=O)CN1C(=O)[C@H](N)[C@H](c2ccccc2)Sc2cc(Cl)ccc21.N>>NC(=O)CN1C(=O)[C@H](N)[C@H](c2ccccc2)Sc2cc(Cl)ccc21,,CO,,,,test
US20100204196A1,CC(C)N.COc1cc2c(cc1Nc1nc3c(ccn3S(=O)(=O)c3ccc(C)cc3)c3nc4cccc(F)c4c(=O)n13)N(C(=O)CN(C)C)CC2>>COc1cc2c(cc1Nc1nc(Nc3cccc(F)c3C(=O)NC(C)C)c3ccn(S(=O)(=O)c4ccc(C)cc4)c3n1)N(C(=O)CN(C)C)CC2,,C1CCOC1,CCOC(C)=O,,,test
US20060247178A1,C=O.CC(C)(C)[Si](OCCC1(c2ccccc2)SC(c2cc(F)ccc2F)=NN1c1nc2c(s1)CNCC2)(c1ccccc1)c1ccccc1>>CN1CCc2nc(N3N=C(c4cc(F)ccc4F)SC3(CCO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)c3ccccc3)sc2C1,,ClCCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20090029987A1,COc1cc(OC)c(C(N)=O)c(C)n1.Cc1cc(C#N)cc(C)c1OCc1ccccc1>>COc1cc(OC)c2c(N)nc(-c3cc(C)c(OCc4ccccc4)c(C)c3)cc2n1,,C1CCOC1,,[Li]CCCC,,test
US05739116,CCOC(=O)CCCBr.COc1cccc(CNc2ccc(C(C)=O)cc2)c1O>>CCOC(=O)CCCOc1c(CNc2ccc(C(C)=O)cc2)cccc1OC,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20090197866A1,CC(C)N(C(=O)Nc1cn(C2CCCCO2)nc1-c1nc2cc(F)c(N3CCCN(C)CC3)cc2[nH]1)C(C)C>>CC(C)N(C(=O)Nc1c[nH]nc1-c1nc2cc(F)c(N3CCCN(C)CC3)cc2[nH]1)C(C)C,,C1COCCO1,,Cl,,test
US20140179689A1,Clc1ccccc1COc1cccc2[nH]ccc12.Nc1nccc(Cl)n1>>Nc1nccc(-n2ccc3c(OCc4ccccc4Cl)cccc32)n1,,CN1CCCC1=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20080293775A1,CN(C)c1ccncc1.NC(=S)Cl.O=C(O)Cc1cc(O)cc(C(F)(F)F)c1>>CN(C)C(=S)Oc1cc(CC(=O)O)cc(C(F)(F)F)c1,CN(C)c1ccncc1,C1COCCO1,O,CCN(CC)CC,,test
US20060167247A1,CC(C)(C)c1cc(C(=O)N2CCNC(=O)C2(C)C)c([N+](=O)[O-])[nH]1>>CC(C)(C)c1cc(C(=O)N2CCNC(=O)C2(C)C)c(N)[nH]1,[Pd],CO,,,,test
US20140315904A1,C=Cc1ccc(F)cc1.O=Cc1cn(C2CCCCO2)nc1I>>O=Cc1cn(C2CCCCO2)nc1/C=C/c1ccc(F)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US07101856B2,COc1ccc(C=Cc2sccc2OC2OC(CO)C(O)C(O)C2O)cc1>>COc1ccsc1C=O,[Pd],,,CO,,test
US20160068531A1,CCS(=O)(=O)CCn1c(CO)cc2cc(Cl)ccc21.CS(=O)(=O)Cl>>CCS(=O)(=O)CCn1c(COS(C)(=O)=O)cc2cc(Cl)ccc21,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20020006948A1,CC(C)(C)C(=O)Cl.OCCCCOc1ccc2nc(-c3ccccc3)n(-c3ccccc3)c2c1>>CC(C)(C)C(=O)OCCCCOc1ccc2nc(-c3ccccc3)n(-c3ccccc3)c2c1,,c1ccncc1,,,,test
US04443451,O=C(c1ccccc1)N1C=CC(c2c[nH]c3ccc(F)cc23)C=C1>>O=C(c1ccccc1)N1CCC(c2c[nH]c3ccc(F)cc23)CC1,[Pd],CC(=O)N(C)C,,[H][H],,test
US20070129367A1,NCc1ccc(F)cc1.O=C(Cl)c1ccc(Cl)nc1>>O=C(NCc1ccc(F)cc1)c1ccc(Cl)nc1,,ClCCl,,CCN(CC)CC,,test
US20130225579A1,BrCCCCCBr.N#Cc1cnc2cc(OC3CCOC3)c(N)cc2c1Nc1ccc(OCc2ccccn2)c(Cl)c1>>N#Cc1cnc2cc(OC3CCOC3)c(N3CCCCC3)cc2c1Nc1ccc(OCc2ccccn2)c(Cl)c1,,ClC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US20100056508A1,COC(CN(CCc1ccc(O)c2[nH]c(=O)ccc12)C(=O)OCc1ccccc1)OC>>O=CCN(CCc1ccc(O)c2[nH]c(=O)ccc12)C(=O)OCc1ccccc1,,CC(C)=O,,Cl,,test
US20120258952A1,CC1(C)OCC(CO)O1.CS(=O)(=O)Cl>>CC1(C)OCC(COS(C)(=O)=O)O1,,ClCCl,,CCN(CC)CC,,test
US20160115128A1,CCOC(=O)CC(c1cccc(OCC2CCNCC2)c1)C1CC1.COc1ccc(C(=O)OCc2ccccc2)c(Cl)n1>>CCOC(=O)CC(c1cccc(OCC2CCN(c3nc(OC)ccc3C(=O)OCc3ccccc3)CC2)c1)C1CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US06291494B1,CCC(=O)NC1Cc2ccc(N)cc2C1.Cl>>Cl.NC1Cc2ccccc2C1,,C1CCOC1,CCOCC,O,,test
US20070060589A1,Cc1nc2cccc(-c3nnc(-c4cc(C(F)(F)F)nn4-c4cccc(CNC(=O)[C@H](C)NC(=O)OC(C)(C)C)c4)o3)c2o1>>Cc1nc2cccc(-c3nnc(-c4cc(C(F)(F)F)nn4-c4cccc(CNC(=O)[C@H](C)N)c4)o3)c2o1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060063787A1,CC#CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2[nH]c(=O)n(C)c(=O)c21.CCOC(=O)C(C)Br>>CC#CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2nc(OC(C)C(=O)O)n(C)c(=O)c21,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20030109523A1,CCn1c(=O)c(CC(=O)O)cc2ccc(OCCCNC(=N)N)cc21.O=C(O)C(F)(F)F>>CCN1C(=O)C(CC(=O)O)Cc2ccc(OCCCNC(=N)N)cc21.O=C(O)C(F)(F)F,[Pd],CO,,[H][H],,test
US04806654,BrB(Br)Br.CCN(CC)CCn1nc2c3c(c(NCCN4C(=O)c5ccccc5C4=O)ccc31)Sc1cc(OC)ccc1-2>>Br.Br.CCN(CC)CCn1nc2c3c(c(NCCN4C(=O)c5ccccc5C4=O)ccc31)Sc1cc(O)ccc1-2,,ClCCl,,CO,,test
US20110166169A1,N#Cc1ccc(-n2c3ccccc3c3c(-c4cnc5ccccc5c4)cccc32)cc1F.NCCc1ccccn1.OO>>NC(=O)c1ccc(-n2c3ccccc3c3c(-c4cnc5ccccc5c4)cccc32)cc1NCCc1ccccn1,,CCO,CS(C)=O,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20080293775A1,CCO.O=C(O)Cc1ccc(Cl)c(O)c1>>CCOC(=O)Cc1ccc(Cl)c(O)c1,,CCO,,CC(=O)Cl,,test
US20020032132A1,CC(C)=CCC/C(C)=C/CO.O=Cc1ccccc1C(=O)O>>CC(C)=CCC/C(C)=C/COC(=O)c1ccccc1C=O,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20040086949A1,C=CCOC(=O)OC(=O)OCC=C.NC(CC(=O)O)CC(=O)O>>C=CCOC(=O)C(C(=O)O)C(N)CC(=O)O,,C1COCCO1,O,CCN(CC)CC,,test
US20070197393A1,C=CCBr.COC(=O)c1ccc(OC)c(C=O)c1O>>C=CCOc1c(C(=O)OC)ccc(OC)c1C=O,,CS(C)=O,,Cl,[K+].[OH-],test
US20060122229A1,CCOC(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)s1.CCOCCN>>CCOCCNC(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)s1,,ClCCl,,CO,,test
US20130172302A1,C1CCCNCC1.O=CC(=O)O.OB(O)c1ccccc1>>O=C(O)C(c1ccccc1)N1CCCCCC1,,ClCCl,,O,,test
US20070293516A1,CC(C)(C)OC(=O)n1ccc2cc(-c3nn(C4CCCC4)c4ncnc(N)c34)ccc21>>CC(C)n1nc(-c2ccc3[nH]ccc3c2)c2c(N)ncnc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US05912246,ClCc1cn2cc(Br)ccc2n1.NC(=O)c1ccc(N2CCNCC2)cc1>>NC(=O)c1ccc(N2CCN(Cc3cn4cc(Br)ccc4n3)CC2)cc1,,OCCO,,CCN(CC)CC,,test
US20110021522A1,COc1cncc(B2OC(C)(C)C(C)(C)O2)c1.Nc1cccc(Br)c1>>COc1cncc(-c2cccc(N)c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20070093521A1,CCOc1cc(CN2CCC(Nc3nc4ccc(C(=O)OC)cc4o3)CC2)ccc1O.COc1ccc(C=O)cc1OCC(C)C>>COC(=O)c1ccc2nc(NC3CCN(Cc4ccc(OC)c(OCC(C)C)c4)CC3)oc2c1,,CC(=O)O,CCO,CCN(C(C)C)C(C)C,[BH3-]C#N.[Na+],test
US20140094459A1,CC(C)(C)OC(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4ccccc4F)cc3)c3c(N)ncnc32)C1>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3F)cc1)nn2[C@@H]1CCCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130059834A1,II.c1cc2[nH]ncc2s1>>Ic1n[nH]c2ccsc12,,CN(C)C=O,,[K+].[OH-],,test
US06140270,COc1ccc(C)cc1.O=C(Cl)c1cc([N+](=O)[O-])ccc1Cl>>COc1ccc(C)cc1C(=O)c1cc([N+](=O)[O-])ccc1Cl,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US06380218B1,BrCc1ccccc1.O=C(O)c1cccnc1Cl>>O=C(OCc1ccccc1)c1cccnc1Cl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20010056123A1,CCOC(=O)C=Cc1ccc(C#N)cc1OC[C@H]1CCCN1C(=O)OC(C)(C)C.Cl>>CCOC(=O)CCc1ccc(C#N)cc1OC[C@H]1CCCN1.Cl,[Pd],C1COCCO1,CCO,[H][H],,test
US04564479,C=CC(=O)OCC.N#Cc1ccccc1Br>>CCOC(=O)C=Cc1ccccc1C#N,[Pd],CN(C)C=O,,CC(=O)[O-].[Na+],,test
US20150232479A1,COC(=O)c1c(OCc2ccccc2)c(=O)c(C(=O)NCc2ccc(F)cc2)cn1CC=O.NC[C@H]1CCCN1>>O=C(NCc1ccc(F)cc1)c1cn2c(c(OCc3ccccc3)c1=O)C(=O)N1C[C@H]3CCCN3[C@@H]1C2,,ClCCl,,CC(=O)O,,test
US04338449,CC(C)=O.CNC(=S)NN.O=C(Cl)c1ccccc1F>>CNC1=NN(C(=O)c2ccccc2F)C(C)(C)S1,,c1ccncc1,,,,test
US20150218092A1,CCc1ccccc1O.O=N[O-]>>CCC1=CC(=NO)C=CC1=O,,CCO,,Cl,,test
US20140288045A1,C=CC(=O)Cl.CCc1cc(Cl)c(Cl)cc1NCC(=O)N1CCNCC1>>C=CC(=O)N1CCN(C(=O)CNc2cc(Cl)c(Cl)cc2CC)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20080280906A1,CC(=O)c1cnc(C)n1C1CCCC1.COC(OC)N(C)C>>Cc1ncc(C(=O)/C=C/N(C)C)n1C1CCCC1,,CN(C)C=O,,,,test
US20150099777A1,CCI.O=Cc1ccc(-c2ccc(F)cc2F)cc1O>>CCOc1cc(-c2ccc(F)cc2F)ccc1C=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040019059A1,C=CC(=O)OC.ON=C(Cl)c1cccnc1>>COC(=O)C1CC(c2cccnc2)=NO1,,CCO,,CCN(CC)CC,,test
US20120053173A1,COS(=O)(=O)OC.O=C(c1oc2ccc(F)cc2c1O)C1CCCCC1>>COc1c(C(=O)C2CCCCC2)oc2ccc(F)cc12,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US04021229,CCC1NCC(C)O1.CS(=O)(=O)Cl>>CCC1OC(C)CN1S(C)(=O)=O,,CCN(CC)CC,,c1ccccc1,,test
US20090171008A1,C#CCOC(=O)C=C.CCCCCCCCCCCCN=[N+]=[N-]>>C=CC(=O)OCc1cn(CCCCCCCCCCCC)nn1,,CN(C)C=O,,O,,test
US20140128372A1,CC(N)[C@H](C)NC(=O)OCc1ccccc1.Cc1nc2c(OCc3c(F)cccc3F)cc(Cl)cn2c1C(=O)O>>Cc1nc2c(OCc3c(F)cccc3F)cc(Cl)cn2c1C(=O)NC(C)[C@H](C)NC(=O)OCc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US04822805,CC(=O)O.Cc1nc(-c2ccccc2N)[nH]c1-c1cccnc1>>CC(=O)Nc1ccccc1-c1nc(C)c(-c2cccnc2)[nH]1,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20120245170A1,CN1CCNCC1.O=Cc1ccc(CBr)o1>>CN1CCN(Cc2ccc(C=O)o2)CC1,,C1COCCO1,,,,test
US20160158207A1,Clc1cc(Br)cc2[nH]ccc12.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cn1cc(-c2cc(Cl)c3cc[nH]c3c2)cn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20160237095A1,COc1nc(S(C)(=O)=O)nc(Nc2ccc3[nH]ncc3c2)c1OC.c1ccc2c(c1)CNC2>>COc1nc(N2Cc3ccccc3C2)nc(Nc2ccc3[nH]ncc3c2)c1OC,,C1COCCO1,,,,test
US20070293478A1,C[C@H]1CNC[C@@H](C)N1.N#Cc1c(Cl)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12>>CC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2C#N)CC(C)N1.Cl,,CC#N,,,,test
US04757081,CC(C(=O)CC(=O)c1ccccc1)C(=O)c1ccccc1Cl.Cc1ccccc1N>>Cc1ccccc1-n1c(-c2ccccc2)cc(=O)c(C)c1-c1ccccc1Cl,,Cc1ccccc1C,,Cc1ccc(S(=O)(=O)O)cc1,,test
US06090825,CC(=O)N1CCC(c2nc(CO)c(-c3ccc(F)cc3)o2)CC1.CI>>COCc1nc(C2CCN(C(C)=O)CC2)oc1-c1ccc(F)cc1,,C1CCOC1,,[H-].[Na+],,test
US20130324551A1,O=[N+]([O-])c1cccc(-c2nc(C3CCOCC3)sc2-c2ccncc2)c1>>Nc1cccc(-c2nc(C3CCOCC3)sc2-c2ccncc2)c1,[Zn],CC(=O)O,CCO,,,test
US20110281842A1,CCCC[Sn](CCCC)(CCCC)c1ccc(C2(O)CCC2)nc1.Cc1ccc(S(=O)(=O)n2c(-c3ccc(CN4CCCC4)cc3)cc3c(Cl)c(Cl)cnc32)cc1>>OC1(c2ccc(-c3c(Cl)cnc4[nH]c(-c5ccc(CN6CCCC6)cc5)cc34)cn2)CCC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,,,test
US20100056576A1,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.Cc1ccc(S(=O)(=O)OC[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)CN=[N+]=[N-])cc1>>Cc1ccc(S(=O)(=O)OC[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)CN=[N+]=[N-])cc1,,CCOC(C)=O,,Cc1cccc(C)n1,,test
US20010011094A1,Cc1cc(C)c(O)c(C)c1.N#Cc1ccc(Nc2nccc(Cl)n2)cc1>>Cc1cc(C)c(Oc2ccnc(Nc3ccc(C#N)cc3)n2)c(C)c1,,C1COCCO1,,O,[H-].[Na+],test
US20130045165A1,CC(C)(C)OC(=O)N1CCC(O)(c2ccc(Cl)cc2)CC1.CCN(CC)S(F)(F)F>>CC(C)(C)OC(=O)N1CCC(F)(c2ccc(Cl)cc2)CC1,,ClCCl,,,,test
US20150175602A1,CC(C)(C)OC(=O)N1CCC(C(F)c2ccc(F)cc2F)CC1.Cl>>Cl.Fc1ccc(C(F)C2CCNCC2)c(F)c1,,C1COCCO1,,,,test
US20100292190A1,C#Cc1cnn(Cc2ccc(OC)cc2)c1.COc1ccc(I)c(OC)c1F>>COc1ccc(Cn2cc(C#Cc3ccc(OC)c(F)c3OC)cn2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,CCN(CC)CC,,,test
US04591548,CCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)N1C(=O)COc2cc([N+](=O)[O-])c(OCc3ccccc3)cc21>>CCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)N1C(=O)COc2cc(N)c(O)cc21,[Pd],C1CCOC1,,[H][H],,test
US08258338B2,CNCC[C@H](O)c1cccs1.Cc1ccc(S(=O)(=O)O)cc1>>CNCC[C@H](OS(=O)(=O)c1ccc(C)cc1)c1cccs1,,CO,,ClCCl,O,test
US20110230493A1,CC(C)(C)OC(=O)N1CCC2(CC1)C[C@H](c1cccc(-c3ccc(F)cc3)c1)CO2.Cl>>Cl.Fc1ccc(-c2cccc([C@@H]3COC4(CCNCC4)C3)c2)cc1,,C1COCCO1,,,,test
US20150376130A1,CCOC(=O)c1cccnc1Cl.NCCc1ccccc1>>CCOC(=O)c1cccnc1NCCc1ccccc1,,O,,CCO,,test
US20080004309A1,CCOC(=O)c1nc(C#N)c2c(c1O)c(Br)c(Br)n2-c1ccc(F)cc1>>CCOC(=O)c1nc(C#N)c2c(ccn2-c2ccc(F)cc2)c1O,[Pd],,,O=C[O-].[NH4+],,test
US20100273764A1,C1=COCCC1.Cc1nc(Cl)c2nc[nH]c2n1>>Cc1nc(Cl)c2ncn(C3CCCCO3)c2n1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20160096839A1,C[C@@H]1CCC[C@H](NC(=O)OC(C)(C)C)c2ccc(C#N)c(c2)-c2c(cnn2C(F)F)NC1=O>>C[C@@H]1CCC[C@H](N)c2ccc(C#N)c(c2)-c2c(cnn2C(F)F)NC1=O,,C1COCCO1,,Cl,,test
US20140011795A1,CC1(C)[C@@H](O)CC[C@@H]1NC(=O)OCc1ccccc1>>CC1(C)[C@@H](N)CC[C@@H]1O,[Pd],CO,,,,test
US04440678,Br.CC(C)C[C@@H](N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)Nc1ccc([N+](=O)[O-])cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>Br.Cc1ccc(S(=O)(=O)N[C@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)Nc2ccc([N+](=O)[O-])cc2)cc1,,CCN(CC)CC,CN(C)C=O,Cl,,test
US04574060,CCO.ClP(c1ccccc1)c1ccccc1>>CCOP(c1ccccc1)c1ccccc1,,CCOCC,,c1ccncc1,,test
US04618683,COc1ccc(Br)c(CC(C#N)C(=O)O)c1OC>>COc1ccc(Br)c(CCC#N)c1OC,,CC(=O)N(C)C,,,,test
US20050182112A1,CN(C)C=O.CNC.O=C1O[C@@H](Cn2cc(C=C(Br)Br)nn2)CN1c1ccc(C2=CCS(=O)(=O)CC2)c(F)c1>>CN(C)C(=O)Cc1cn(C[C@H]2CN(c3ccc(C4=CCS(=O)(=O)CC4)c(F)c3)C(=O)O2)nn1,,CN(C)C=O,,O,,test
US04387103,CC(C)N.COC(=O)c1ccccc1OCC1CO1>>COC(=O)c1ccccc1OCC(O)CNC(C)C,,CO,,,,test
US04473560,COP(OC)OC.O=C(Cl)Cc1ccc(Cl)cc1>>COP(=O)(OC)C(O)=Cc1ccc(Cl)cc1,,CCOCC,,,,test
US20100216814A1,CCOC(=O)C=C(Cn1c2c(c3cc(C)ccc31)CN(C)CC2)c1ccc(F)cc1>>Cc1ccc2c(c1)c1c(n2C/C(=C/C(=O)O)c2ccc(F)cc2)CCN(C)C1,,CN1CCCC1=O,,Cl,[K+].[OH-],test
US04719207,CN1C(=O)C[C@H]1C(=O)OCc1ccccc1>>CN1C(=O)C[C@H]1C(=O)O,[Pd],CO,,[H][H],,test
US20030191133A1,BrCCCBr.O=C1CCc2ccccc2N1>>O=C1CCc2ccccc2N1CCCBr,,CN(C)C=O,,[H-].[Na+],,test
US20100029722A1,Cc1cc(C#N)sc1C(=O)NCc1ccccc1.NNC(=O)Cc1ccccc1>>Cc1cc(-c2n[nH]c(Cc3ccccc3)n2)sc1C(=O)NCc1ccccc1,,CCCCO,,O=C([O-])[O-].[K+].[K+],,test
US03984432,CCOP(=O)(OCC)C(C)(C)N.O=C(Cl)c1cccc([N+](=O)[O-])c1>>CCOP(=O)(OCC)C(C)(C)NC(=O)c1cccc([N+](=O)[O-])c1,,CC#N,,CCN(CC)CC,,test
US20100152265A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)[Si](Oc1ccc2c(Cl)n[nH]c2c1)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)n1nc(Cl)c2ccc(O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)cc21,,C1CCOC1,,CCN(CC)CC,CCOC(C)=O,test
US20150368270A1,COCCl.Oc1c(F)cccc1Br>>COCOc1c(F)cccc1Br,,ClCCl,,CCN(C(C)C)C(C)C,,test
US06111109,CN(C)CCN.COC(=O)c1cccc2cc3ccccc3nc12>>CN(C)CCNC(=O)c1cccc2cc3ccccc3nc12,,CCCO,,N#N,,test
US05719166,CC(C)(C)OC(=O)N1CCC(Cc2cccnc2)CC1>>c1cncc(CC2CCNCC2)c1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20050277630A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)OCCC(=CN(C)C)C3=O)C(=O)O1.NN>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)OCCc2cn[nH]c2-3)C(=O)O1,,CCO,,,,test
US20100298301A1,NCc1ccc(-c2oc(-c3c(F)cccc3F)nc2C(N)=O)cc1.O=S(=O)(Cl)c1ccc(F)cc1>>NC(=O)c1nc(-c2c(F)cccc2F)oc1-c1ccc(CNS(=O)(=O)c2ccc(F)cc2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20100273816A1,CS(=O)(=O)c1cccc(Br)c1.Oc1ccc(F)c(-c2ncnc3c(C(F)(F)F)cccc23)c1>>CS(=O)(=O)c1cccc(Oc2ccc(F)c(-c3ncnc4c(C(F)(F)F)cccc34)c2)c1,[Cu]I,C1COCCO1,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US06451790B1,CON=C(C1=NOCCO1)c1ccccc1CCl.Oc1ccn(-c2ccc(Cl)cc2)n1>>CON=C(C1=NOCCO1)c1ccccc1COc1ccn(-c2ccc(Cl)cc2)n1,,CN(C)C=O,,O,[H-].[Na+],test
US20140315949A1,COC(=O)COc1cc(Br)ccc1C(C)=O>>CC(=O)c1ccc(Br)cc1OCC(=O)O,,C1CCOC1,,O,[Na+].[OH-],test
US20020022605A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O[C@@H](CNC1CN(C(c2ccccc2)c2ccccc2)C1)COc1ccc(OCc2ccccc2)cc1>>CC(C)(C)OC(=O)N(C[C@H](O)COc1ccc(OCc2ccccc2)cc1)C1CN(C(c2ccccc2)c2ccccc2)C1,,ClCCl,,,,test
US20040077618A1,CCOC(=O)C1CC1(C1CC1)C1CC1>>O=C(O)C1CC1(C1CC1)C1CC1,,O,,[Na+].[OH-],,test
US20160108027A1,CC(Cl)C(=O)N(Cc1ccccc1)[C@H](C)CO>>CC1OC[C@@H](C)N(Cc2ccccc2)C1=O,,CC(C)O,,CC(C)(C)[O-].[K+],,test
US20160016948A1,CC(C)n1c(C(=O)N2CCN(C)CC2)nc2cnc(Br)cc21.COC1CCN(c2nccc(N)n2)CC1>>COC1CCN(c2nccc(Nc3cc4c(cn3)nc(C(=O)N3CCN(C)CC3)n4C(C)C)n2)CC1,,C1COCCO1,,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20150232463A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc(C)c(-c2ccc(C)c(OCc3ccccc3)c2)c1N1CCC(C)(C)CC1>>Cc1ccc(-c2c(C)nc(C)c([C@H](OC(C)(C)C)C(=O)O)c2N2CCC(C)(C)CC2)cc1OCc1ccccc1,,CCO,,[Na+].[OH-],,test
US06812218B2,CCCCCCCCCCCCCCN(CCCCCCCCCCCCCC)C(=O)CCC(=O)NCCNC(=S)NCCNC(=S)NCCNC(=S)NCCN.CN=C=S>>CCCCCCCCCCCCCCN(CCCCCCCCCCCCCC)C(=O)CCC(=O)NCCNC(=S)NCCNC(=S)NCCNC(=S)NCCNC(=S)NC,,ClCCl,,CCN(CC)CC,,test
US08304419B2,CC(O)c1nc(Br)c(Br)n1COCC[Si](C)(C)C.CI>>COCc1nc(Br)c(Br)n1COCC[Si](C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US03960850,COC(=O)Cl.O=C(O)C(O)c1ccccc1>>COC(=O)OC(C(=O)O)c1ccccc1,,C1CCOC1,,CN(C)c1ccccc1,,test
US20120171703A1,Nc1ncc(-c2ccccc2)nc1Br.Sc1nc2ccccc2s1>>Nc1ncc(-c2ccccc2)nc1Sc1nc2ccccc2s1,,CN(C)C=O,,[H-].[Na+],,test
US07179823B1,CCOC(=O)Cc1c[nH]nc1-c1ccccc1.Cc1oc(-c2ccccc2)nc1CCOc1ccc(CCl)cn1>>CCOC(=O)Cc1cn(Cc2ccc(OCCc3nc(-c4ccccc4)oc3C)nc2)nc1-c1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US20010001799A1,CC(C)(CO)CO.COc1cc(Br)c(C=O)cc1OC>>COc1cc(Br)c(C2OCC(C)(C)CO2)cc1OC,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080021056A1,CC1CC(=O)c2ccccc2N1S(=O)(=O)c1ccccn1.COC(OC)N(C)C.NN>>CC1c2cn[nH]c2-c2ccccc2N1S(=O)(=O)c1ccccn1,,CC(=O)O,,O,,test
US06872718B1,C=C(C)CCl.Cc1cc(O)c(C)c2c1N(C=O)C(C)(C)C2>>C=C(C)COc1cc(C)c2c(c1C)CC(C)(C)N2C=O,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20080312226A1,CC1CNCCN1c1nc(-c2ccccc2)ns1>>CC1CNCCN1c1nc(-c2ccccc2)ns1,,[Na+],[OH-],Cl,,test
US20030149027A1,CC(C)(C)OC(=O)NCc1ccc(N2C(=O)C(CC(=O)NCc3ccccc3F)C(=O)N(Cc3ccc(OCc4ccccc4)cc3)c3ccccc32)cc1.Cl>>Cl.NCc1ccc(N2C(=O)C(CC(=O)NCc3ccccc3F)C(=O)N(Cc3ccc(OCc4ccccc4)cc3)c3ccccc32)cc1,,CCOC(C)=O,,,,test
US20120094972A1,COC(=O)C(C(=O)OC)c1ncc(Br)cc1[N+](=O)[O-]>>COC(=O)Cc1ncc(Br)cc1[N+](=O)[O-],,O,,[Cl-].[Li+],,test
US20130072467A1,CCN.O=C1NC(=S)CS1>>CCNC1=NC(=O)SC1,,CCO,,,,test
US20110288063A1,CCOC(=O)c1nn(CCOC)c2c1C1CCC2C1>>COCCn1nc(CO)c2c1C1CCC2C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110046259A1,COc1cc(C=O)ccc1O.OCCBr>>COc1cc(C=O)ccc1OCCO,,CCO,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20130237525A1,COc1cccc(F)c1C1CC(C)C(=O)N1Cc1ccc(OC(F)(F)F)cc1>>CC1CC(c2c(O)cccc2F)N(Cc2ccc(OC(F)(F)F)cc2)C1=O,,ClCCl,,O,,test
US05854268,BrCc1ccccc1.CC(C)(C)OC(=O)N1CC[C@@H](O)C1>>CC(C)(C)OC(=O)N1CC[C@@H](OCc2ccccc2)C1,,C1CCOC1,,O,[H-].[Na+],test
US06432952B1,C1CCNCC1.CC(C)O.O=Cc1c[nH]nn1>>CN(C)Cc1n[nH]nc1C=O,,CC(C)O,O,O=C(O)C(F)(F)F,,test
US20050277668A1,COc1ccc(NC2CCN([C@H](C)CCNC(=O)OC(C)(C)C)CC2)cc1.N#Cc1cccc(CBr)n1>>COc1ccc(N(Cc2cccc(C#N)n2)C2CCN([C@H](C)CCNC(=O)OC(C)(C)C)CC2)cc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20150225401A1,CC(C)(C)OC(=O)N1CC(CN(C(=O)C(F)(F)F)[C@@H]2C[C@H]2c2ccccc2)C1>>O=C(N(CC1CNC1)[C@@H]1C[C@H]1c1ccccc1)C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090048454A1,CCOC(=O)C12CCC(N)(CC1)CC2.N#C[C@@H]1C[C@H](F)CN1C(=O)COS(=O)(=O)c1ccccc1>>CCOC(=O)C12CCC(NCC(=O)N3C[C@@H](F)C[C@H]3C#N)(CC1)CC2,,CN(C)C=O,,Cl,[I-].[K+],test
US20110052578A1,C[C@@H](CNc1nccc(-c2c(Br)nc(C3CCC3)n2COCC[Si](C)(C)C)n1)NC(=O)OC(C)(C)C>>C[C@H](N)CNc1nccc(-c2[nH]c(C3CCC3)nc2Br)n1,,CO,Cl,,,test
US20140302010A1,CC(C)CNc1cccc2c1ncn2-c1ccc(C(=O)O)cc1.NC1CC1>>CC(C)CNc1cccc2c1ncn2-c1ccc(C(=O)NC2CC2)cc1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05968982,BrCCCCCCCCCBr.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>BrCCCCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-],,Cc1ccccc1,,,,test
US20060110743A1,CCOC(=O)c1ccc(N)c(OC)c1>>COc1cc(C(=O)O)ccc1N,,CO,,[Na+].[OH-],,test
US20100152236A1,C=CC[Mg]Br.C[C@@H](C=O)NC(=O)OCc1ccccc1>>C=CCC(O)[C@H](C)NC(=O)OCc1ccccc1,,C1CCOC1,,O,,test
US20130150339A1,COc1cc(-c2cccc(F)c2)c(Cl)cc1-c1ncnc2cc(S(=O)(=O)Oc3c(F)c(F)c(F)c(F)c3F)ccc12.Nc1ccncn1>>COc1cc(-c2cccc(F)c2)c(Cl)cc1-c1ncnc2cc(S(=O)(=O)Nc3ccncn3)ccc12,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20030018026A1,Cc1cc(C(=O)N2Cc3ccc(C(=O)N4CCNCC4)n3Cc3ccccc32)ccc1-c1ccccc1C(F)(F)F.OC[C@H]1CO1>>Cc1cc(C(=O)N2Cc3ccc(C(=O)N4CCN(C[C@@H](O)CO)CC4)n3Cc3ccccc32)ccc1-c1ccccc1C(F)(F)F,,CO,,CCN(C(C)C)C(C)C,Cl,test
US20090275612A1,CCN(CC)CCCC(C)Nc1cc(/C=C/c2ccccc2Cl)nc2cc(Cl)ccc12.O=C(O)/C=C/c1cnc[nH]1.O=C(n1ccnc1)n1ccnc1>>CN(CCNC(=O)C=Cc1c[nH]cn1)CCNc1ccnc2cc(Cl)ccc12,,C1CCOC1,,,,test
US20040072829A1,C(=Cc1ccccc1)CN1CCNCC1.COc1ccc(CCNc2nc(Cl)nc(N(C)CCCc3ccc(Cl)cc3)n2)cc1>>CN(CCCc1ccc(Cl)cc1)c1nc(NCCc2ccc(O)cc2)nc(N2CCN(C/C=C/c3ccccc3)CC2)n1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US04157347,C#CC(C)(C)N.CSC(=NC#N)SC>>C#CC(C)(C)N=C(NC#N)SC,,CC#N,,,,test
US20110207770A1,CS(=O)(=O)O[C@@H]1CN2CCC1CC2.Fc1cccc(S)c1>>Fc1cccc(S[C@H]2CN3CCC2CC3)c1,,CN(C)C=O,,[H-].[Na+],,test
US05366972,Cc1c(Br)c(N(C)C)nc(Cl)c1C#N.O=S(=O)(O)O>>Cc1c(Br)c(N(C)C)nc(Cl)c1C(N)=O,,O,O=S(=O)(O)O,O=C([O-])[O-].[Na+].[Na+],,test
US20060135773A1,CCOP(=O)(OCC)C(F)(F)c1ccc(C)cc1Cl.O=C1CCC(=O)N1Br>>CCOP(=O)(OCC)C(F)(F)c1ccc(CBr)cc1Cl,,c1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20040248951A1,COC(=O)COc1ccc([N+](=O)[O-])cc1I>>COC(=O)COc1ccc(N)cc1I,[Fe],CO,O,[Cl-].[NH4+],,test
US20150291554A1,N#CBr.NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn(C2CC3CC2CN3)c1N>>N#CN1CC2CC1CC2n1nc(-c2ccc(Oc3ccccc3)cc2)c(C(N)=O)c1N,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US05120368,CC(=O)CCC(C(=O)O)C(C)C.O=C(Cl)C(=O)Cl>>CC(=O)CCC(C(=O)Cl)C(C)C,,c1ccccc1,,,,test
US20100168080A1,CS(=O)(=O)Cl.OCCCn1cnc2cc(Cl)ccc21>>CS(=O)(=O)OCCCn1cnc2cc(Cl)ccc21,,ClCCl,,CCN(CC)CC,,test
US20120015943A1,COC(=O)c1ccc2c(c1)CCC(S(=O)(=O)C(F)(F)F)=C2.COc1ccc(B(O)O)cc1>>COC(=O)c1ccc2c(c1)CCC(c1ccc(OC)cc1)=C2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US20120238545A1,CCOC(=O)c1nn(C2CCOCC2)c2c1CS(=O)(=O)c1sc(NC(=O)OC(C)(C)C)nc1-2>>CCOC(=O)c1nn(C2CCOCC2)c2c1CS(=O)(=O)c1sc(N)nc1-2,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20100317568A1,Nc1ccc(C2CCC(c3ccc(N)c([N+](=O)[O-])c3)N2c2ccc(F)cc2)cc1[N+](=O)[O-]>>Nc1ccc(C2CCC(c3ccc(N)c(N)c3)N2c2ccc(F)cc2)cc1N,O=[Pt],CN(C)C=O,,C1CCOC1,,test
US20080085886A1,CN(C)C(=O)c1oc2c(CO)cncc2c1Nc1ccc(I)cc1F.Oc1ccccc1>>CN(C)C(=O)c1oc2c(COc3ccccc3)cncc2c1Nc1ccc(I)cc1F,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150133425A1,CCOC(=O)C1CCc2c(sc3ncnc(Cl)c23)C1.Nc1cc2cn[nH]c2cc1F>>CCOC(=O)C1CCc2c(sc3ncnc(Nc4cc5cn[nH]c5cc4F)c23)C1,,CCO,O,C1COCCO1,Cl,test
US20120142705A1,COC(=O)C(Br)CC(C)C.O=C1Nc2ccc(Br)cc2C1=O>>COC(=O)C(CC(C)C)N1C(=O)C(=O)c2cc(Br)ccc21,,CN(C)C=O,O,[H-].[Na+],,test
US20040115165A1,CCOCC.O=C(Oc1ccccn1)Oc1ccccn1.O=C1C=CC(=O)N1CCCC(F)(F)C(F)(F)C(F)(C(=O)[O-])c1ccccc1>>CCOC(CCN)OCC,,CCOCC,ClCCl,,,test
US20100298324A1,COc1cnc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)nc1OC.Nc1ccc(C(=O)c2ccccc2)cc1>>COc1cnc(-n2c(=S)[nH]c3cc(C(=O)Nc4ccc(C(=O)c5ccccc5)cc4)ccc3c2=O)nc1OC,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130274460A1,Cc1ccc(SCF)cc1.O=C1CCC(=O)N1Br>>Cc1ccc(S(=O)CF)cc1,,O,,CO,,test
US20160145247A1,COC(=O)Cc1ccccc1OCc1cccc(-c2cccc(CN(C)C(=O)OC(C)(C)C)c2)c1.Cl>>CNCc1cccc(-c2cccc(COc3ccccc3CC(=O)OC)c2)c1.Cl,,C1COCCO1,,,,test
US20060142247A1,CC1(C)C(=O)N(CCN)c2cc3[nH]c(-c4n[nH]c5ccccc45)nc3cc21.O=C=NCc1ccccc1>>CC1(C)C(=O)N(CCNC(=O)NCc2ccccc2)c2cc3[nH]c(-c4n[nH]c5ccccc45)nc3cc21,,CN(C)C=O,,CCN(CC)CC,O,test
US20090227628A1,COc1ccccc1CNc1ccc2c([N+](=O)[O-])cccc2n1>>COc1ccccc1CNc1ccc2c(N)cccc2n1,[Pd],CO,,[H][H],,test
US20050037999A1,CON(C)C(=O)c1cccc(I)c1.Clc1ncnc2c1c(Br)cn2C1CCCC1>>O=C(c1cccc(I)c1)c1cn(C2CCCC2)c2ncnc(Cl)c12,,C1CCOC1,,[Li]CCCC,,test
US20140343032A1,COC(=O)C1=C(CN2C3COCC2CN(C(=O)OC(C)(C)C)C3)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl.ClCCl>>COC(=O)C1=C(CN2C3COCC2CN(C(C)=O)C3)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20050245518A1,COC(=O)c1ccc(CN)cc1.Clc1nccc(-c2ccsc2)n1>>COC(=O)c1ccc(CNc2nccc(-c3ccsc3)n2)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20120214786A1,Cn1c(Nc2c(Cl)ccc(CNC(=O)OC(C)(C)C)c2Cl)nc2cc(C(=O)Nc3ccc(F)c(Cl)c3)c(OCC(F)F)cc21>>Cn1c(Nc2c(Cl)ccc(CN)c2Cl)nc2cc(C(=O)Nc3ccc(F)c(Cl)c3)c(OCC(F)F)cc21,,C1COCCO1,,Cl,,test
US05223518,BrC(Br)(Br)Br.O=Cc1cccs1>>BrC(Br)=Cc1cccs1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20120015943A1,CN(C)CCCl.COC(=O)c1ccc2c(c1)CC(c1cccc(O)c1)CC2>>COC(=O)c1ccc2c(c1)CC(c1cccc(OCCN(C)C)c1)CC2,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100286118A1,CC(C)(C)OC(=O)NC1(C(=O)N[C@@H](Cc2ccc(I)cc2)C(N)=O)CCOCC1.CS(=O)(=O)Oc1cccc(B(O)O)c1>>CC(C)(C)OC(=O)NC1(C(=O)N[C@@H](Cc2ccc(-c3cccc(OS(C)(=O)=O)c3)cc2)C(N)=O)CCOCC1,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20120214735A1,COC(=O)c1nc(NC(=O)C(OC2CCOCC2)c2ccc(S(=O)(=O)C3CC3)cc2)sc1C>>Cc1sc(NC(=O)C(OC2CCOCC2)c2ccc(S(=O)(=O)C3CC3)cc2)nc1CO,,Cc1ccccc1,,CC(C)C[AlH]CC(C)C,,test
US07126028B1,CC[C@@H](C)[C@H](N)C(O)(c1ccccc1)c1ccccc1.O=C(Cl)OC(Cl)(Cl)Cl>>CC[C@@H](C)[C@@H]1NC(=O)OC1(c1ccccc1)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20160237075A1,C=CC(=O)N1CCC(c2ccc(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)n2)C1.CN(C)C(On1nnc2cccnc21)=[N+](C)C.CN(C)CC=CC(=O)O>>CN(C)CC=CC(=O)N1CCC(n2cc(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)n2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US09181235B2,COc1ccc(CNCc2ncc(Br)cc2C)c(OC)c1.Cc1cc(-c2ccc(CN)cc2F)ccn1>>COc1ccc(CNCc2ncc(-c3ccnc(C)c3)cc2C)c(OC)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,Cc1ccccc1,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20050020654A1,O=C1CSC(=O)N1.O=Cc1ccc(O)c(C(=O)O)c1>>O=C1NC(=O)/C(=C/c2ccc(O)c(C(=O)O)c2)S1,,Cc1ccccc1,O,C1CCNCC1,CC(=O)O,test
US20140378459A1,CN(C)C(OC(C)(C)C)OC(C)(C)C.O=C(NCCc1ccc(C(=O)O)cc1)OCc1ccccc1>>CC(C)(C)OC(=O)c1ccc(CCNC(=O)OCc2ccccc2)cc1,,Cc1ccccc1,,,,test
US20050014812A1,CC(=O)OC(C)=O.Cc1cc(Br)cc(N)c1N>>Cc1nc2c(C)cc(Br)cc2[nH]1,,CC(=O)O,CCO,O=S(=O)(O)O,O=C([O-])[O-].[Na+].[Na+],test
US04107430,CN1CCN(CC/C=C2/c3ccccc3Sc3ccc(S(=O)(=O)N(C)C)cc32)CC1>>CN1CCN(CC/C=C2\c3ccccc3Sc3ccc(S(=O)(=O)N(C)C)cc32)CC1,,O,,ClCCl,[Na+].[OH-],test
US20100197651A1,CN(C)C=CC(=O)c1nn(-c2cccc(OC(F)F)c2)ccc1=O.NNc1ccccc1>>O=c1ccn(-c2cccc(OC(F)F)c2)nc1-c1ccnn1-c1ccccc1,,CO,,,,test
US20100120859A1,COC(=O)c1ccc(CBr)cc1.COCCCc1cc(O)cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)c1>>COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)cc(OCc2ccc(C(=O)OC)cc2)c1,,CCOCC,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US06281231B1,CC(C)(C)[Si](C)(C)Cl.CN(C)C=O.ClCc1cc(Cl)nc(Cl)c1>>CC(C)(C)[Si](C)(C)OCc1cc(Cl)nc(Cl)c1,,CCOC(C)=O,,c1c[nH]cn1,,test
US20150126498A1,COc1ncc([N+](=O)[O-])cc1CNC(=O)OC(C)(C)C>>COc1ncc(N)cc1CNC(=O)OC(C)(C)C,[Pd],CO,ClCCl,,,test
US20100081675A1,N#Cc1cnc2ccsc2c1NCCc1cnc(N)s1.O=C=Nc1cccc(Cl)c1>>N#Cc1cnc2ccsc2c1NCCc1cnc(NC(=O)Nc2cccc(Cl)c2)s1,,ClCCl,,,,test
US04012524,CC1(C)Cc2cc(O)c(Cl)c(Cl)c2C1O.CCOC(=O)CBr>>CC1(C)Cc2cc(OCC(=O)O)c(Cl)c(Cl)c2C1O,,CN(C)C=O,,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US04552876,COc1ccc(CCCCCCc2ccc(OC)cc2)cc1>>Oc1ccc(CCCCCCc2ccc(O)cc2)cc1,,CCOCC,,Br,CC(=O)O,test
US20050107408A1,C[C@H](N)CO.C[C@H](O)Cn1c(=O)c(Oc2ccc(F)cc2F)cc2cnc(S(C)(=O)=O)nc21>>C[C@H](O)Cn1c(=O)c(Oc2ccc(F)cc2F)cc2cnc(N[C@@H](C)CO)nc21,,C1CCOC1,,,,test
US20020103247A1,Brc1ccc2c(c1)CCN2.CC(C)(C)OC(=O)OC(=O)[O-]>>CC(C)(C)OC(=O)N1CCc2cc(Br)ccc21,,ClCCl,,,,test
US20130331349A1,c1ccc(COCC2CCCCC23CC3)cc1>>OCC1CCCCC12CC2,,CCOC(C)=O,CO,[H][H],,test
US20080027099A1,BrC1CCCC1.COC(=O)c1ccc(OC)c(O)c1[N+](=O)[O-]>>COC(=O)c1ccc(OC)c(OC2CCCC2)c1[N+](=O)[O-],,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110053958A1,COc1cccc(Nc2ccccc2)c1.ClCCl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cccc(N(C(=O)Cl)c2ccccc2)c1,,ClCCl,,c1ccncc1,,test
US06350749B1,Cc1ccc(S(=O)(=O)NNC2=CC(=O)CC(c3ccccc3Cl)C2)cc1.O=C(CBr)c1ccc(Cl)cc1>>O=C1CC(c2ccccc2Cl)Cc2nncc(-c3ccc(Cl)cc3)c21,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20090270405A1,Brc1cccc(NC2=NCC3(CN4CCC3CC4)O2)n1>>c1ccc(NC2=NCC3(CN4CCC3CC4)O2)nc1,[Pd],CO,,,,test
US20100137397A1,CC(C)(C)OC(=O)COC[C@@H]1c2ccccc2C[C@H]1N.O=C(O)c1cc2cc(Cl)sc2[nH]1>>CC(C)(C)OC(=O)COC[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)sc2[nH]1,,CC(=O)N(C)C,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20060052371A1,CC(C)(C)OC(=O)CBr.N#Cc1cccc(O)c1>>CC(C)(C)OC(=O)COc1cccc(C#N)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US09018370B2,CC#N.CCOP(=O)(CC[C@H]1O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O)OCC.C[Si](C)(C)Br.c1ccncc1>>CC(=O)OC[C@H]1O[C@H](CCP(=O)([O-])[O-])[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O.CC[NH+](CC)CC.CC[NH+](CC)CC,,CC#N,,,,test
US20130059835A1,CCOC(=O)/C=C/B1OC(C)(C)C(C)(C)O1.CCOc1c(C2(C)OCCO2)cc(Cl)c(F)c1I>>CCOC(=O)/C=C/c1c(F)c(Cl)cc(C2(C)OCCO2)c1OCC,,C1COCCO1,O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20140213586A1,Nc1ccc2[nH]c(=O)oc2c1.O=C(c1c[nH]c2ccccc12)C(Cl)c1ccccc1>>O=C(c1c[nH]c2ccccc12)C(Nc1ccc2[nH]c(=O)oc2c1)c1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US08575118B2,COC(=O)NC(C(=O)N1CC2(CC1c1ncc(-c3ccc(Br)cc3)[nH]1)OCCO2)C(C)C>>COC(=O)NC(C(=O)N1CC(=O)CC1c1ncc(-c2ccc(Br)cc2)[nH]1)C(C)C,,CC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04872901,CCOC(=O)c1c(C)nn(C)c1SCc1ccccc1>>Cc1cc(SCc2ccccc2)n(C)n1,,O,,Cl,,test
US20100152160A1,O=C1COC(Cc2ccc(F)cc2)CCN1Cc1ccccc1>>Fc1ccc(CC2CCN(Cc3ccccc3)CCO2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120059028A1,COC(=O)CCC(C)=O.Nc1sc2c(c1C(=O)c1ccc(Cl)c(Cl)c1)CCCC2>>COC(=O)Cc1c(C)nc2sc3c(c2c1-c1ccc(Cl)c(Cl)c1)CCCC3,,CN(C)C=O,,C[Si](C)(C)Cl,,test
US04012380,CC(=O)C1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)C(NC(=O)Cc3cccs3)[C@H]2SC1>>CC(=O)C1=C(C(=O)O)N2C(=O)C(NC(=O)Cc3cccs3)[C@H]2SC1,,CCCCCCC,,COc1ccccc1,O=C(O)C(F)(F)F,test
US20110046132A1,CCOC(=O)c1cnn(-c2nc3nc4ccccc4nc3[nH]2)c1>>O=C(O)c1cnn(-c2nc3nc4ccccc4nc3[nH]2)c1,,C1CCOC1,,[K+].[OH-],,test
US20020137961A1,CC(C)(C)[Si](C)(C)Oc1ccc([C@@H]2CC[C@@H](O)CC2)c(O[Si](C)(C)C(C)(C)C)c1.O=C=Nc1ccccc1>>CC(C)(C)[Si](C)(C)Oc1ccc([C@@H]2CC[C@@H](OC(=O)Nc3ccccc3)CC2)c(O[Si](C)(C)C(C)(C)C)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160102107A1,CCOC(=O)C(Nc1cc(C)c2nnc(C)n2c1)c1ccc(Cl)cc1.COc1ncccc1C(=O)CC(=O)SC(C)(C)C>>CCOC(=O)C(c1ccc(Cl)cc1)N(C(=O)CC(=O)c1cccnc1OC)c1cc(C)c2nnc(C)n2c1,,CCOC(C)=O,CO,,,test
US20110224155A1,C/C=C\c1cccc(N)c1C#N>>CCCc1cccc(N)c1C#N,[Pd],CCO,,,,test
US07531534B2,CCOC(=O)CC(=O)CCl.O=[N+]([O-])c1ccc2ncsc2c1>>CCOC(=O)/C=C1\CSc2ccccc2N1,,CCO,,Cl,[K+].[OH-],test
US20140206700A1,CCn1nc(C2CCNCC2)nc1-c1cnc(N)c(-c2nnc(C(C)(C)C)o2)n1.O=C(O)CCOC1CCCCO1>>CCn1nc(C2CCN(C(=O)CCOC3CCCCO3)CC2)nc1-c1cnc(N)c(-c2nnc(C(C)(C)C)o2)n1,,CC#N,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140142083A1,CCN(c1cc(Cl)cc(C(=O)OC)c1OC)C1CCOCC1>>CCN(c1cc(Cl)cc(C(=O)O)c1OC)C1CCOCC1,,C1CCOC1,,Cl,[Na+].[OH-],test
US05516774,Cc1ccccc1CC(=O)Cl.Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1>>Cc1ccccc1CC(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1,,ClCCl,,CCN(CC)CC,,test
US20100324284A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(B3OC(C)(C)C(C)(C)O3)cn2)cc1.CS(=O)(=O)N1CCc2c(Cl)nc(N3CCOCC3)nc21>>COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4S(C)(=O)=O)cn2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140179680A1,CC[C@@H]1[C@@H](C)OCC(=O)N1Cc1ccccc1>>CC[C@@H]1[C@@H](C)OCCN1Cc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20130045942A1,CC(=O)C(O)[C@H]1O[C@@H](N2CN=C3C2=NC=NC3(N)Br)C[C@@]1(O)C(C)=O.COc1cc(C(C)N)cc(OC)c1OC>>COc1cc(C(C)Nc2ncnc3c2ncn3[C@H]2C[C@@](O)(C(C)=O)[C@@H](C(O)C(C)=O)O2)cc(OC)c1OC,,CCO,,CCN(CC)CC,Cl,test
US04486427,CCCCCCCCCCCCS(=O)(=O)Cl.O=[N+]([O-])C=C1NCCCS1>>CCCCCCCCCCCCS(=O)(=O)N1CCCSC1=C[N+](=O)[O-],,O,,CCN(C(C)C)C(C)C,ClCCl,test
US20150274738A1,CC(C)(C)OC(=O)NCCBr.COc1cc(-c2nn(C3CCC(N4CCN(C(=O)OC(C)(C)C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C>>COc1cc(-c2nn(C3CCC(N4CCN(CCNC(=O)OC(C)(C)C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US05885985,Fc1ccccc1N=C=S.N>>NC(=S)Nc1ccccc1F,,CCOCC,,,,test
US20040092559A1,CCOC(=O)CN(CCC(C)=O)C(=O)OC(C)(C)C>>CCOC(=O)C1N(C(=O)OC(C)(C)C)CCC1(C)O,,Cc1ccccc1,,CC(C)(C)[O-].[K+],,test
US20110172224A1,CC(C)(C)[Si](C)(C)OCCn1cc2c(n1)CCc1c-2sc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c12>>OCCn1cc2c(n1)CCc1c-2sc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c12,,C1CCOC1,,Cl,,test
US20070293507A1,COC(=O)c1cc(-c2ccccc2)n[nH]1>>O=C(O)c1cc(-c2ccccc2)n[nH]1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20140112945A1,COc1ccc(C2=NN(C3CCN(C(=O)[C@H](CCC(=O)OCc4ccccc4)NC(=O)OC(C)(C)C)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](N)CCC(=O)OCc4ccccc4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC,,C1COCCO1,Cl,,,test
US20120059002A1,COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(OCCN)c(C)c3)nc2c1.Cc1noc(C(Cl)(Cl)Cl)n1>>COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(OCCNc4nc(C)no4)c(C)c3)nc2c1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20060148858A1,CC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO.COC(=O)Cc1cccc(C(C)C)c1O>>COC(=O)Cc1cccc(C(C)C)c1OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1C(C)C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20150126498A1,COc1ccc(N)cc1OC.O=S(=O)(Cl)c1cccnc1Cl>>COc1ccc(NS(=O)(=O)c2cccnc2Cl)cc1OC,,C1COCCO1,,,,test
US04284794,Cc1ccc(S(=O)(=O)O)cc1.O=C([O-])c1ccccc1-c1c2cc(Br)c(=O)c(Br)c-2oc2c(Br)c([O-])c(Br)cc12.[Na+].[Na+].c1ccccc1>>CCC1(C)OCCO1.O=C([O-])c1ccccc1-c1c2cc(Br)c(=O)c(Br)c-2oc2c(Br)c([O-])c(Br)cc12.[Na+].[Na+],,c1ccccc1,,,,test
US20140171435A1,CI.O=S1(=O)NCc2cc(Br)ccc21>>CN1Cc2cc(Br)ccc2S1(=O)=O,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20100266504A1,CC(C)[Mg]Cl.CC1(C)CN(Cc2ccccc2)Cc2ccc(Cl)nc21>>CC(C)c1ccc2c(n1)C(C)(C)CNC2.Cl,,C1CCOC1,,,,test
US05476933,COc1cc(O)ccc1O>>COC1=CC(=O)C=CC1=O,,O,,,,test
US05252732,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(O)C(O)C3)C(C)C(O)CC1=O)C(C)CC2OC>>CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(O[Si](C)(C)C(C)(C)C)C(O)C3)C(C)C(O)CC1=O)C(C)CC2OC,,CCOC(C)=O,ClCCl,Cc1cccc(C)n1,,test
US20040235667A1,Fc1cc(F)c(F)nc1F.Oc1csc(C(F)(F)F)c1>>Fc1cc(F)c(Oc2csc(C(F)(F)F)c2)nc1F,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20070105943A1,COC(=O)c1nc(Cl)c(N)nc1N>>COC(=O)c1ncc(N)nc1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,CCN(CC)CC,O=CO,test
US04230628,COC(=O)CCCCCCCCCCCCCCCN(C(=O)OC(C)(C)C)c1ccc(C(=O)n2ccnc2)cc1.NCC(O)CO>>COC(=O)CCCCCCCCCCCCCCCNc1ccc(C(=O)NCC(O)CO)cc1,,ClC(Cl)Cl,,[Na+].[OH-],,test
US20040138454A1,CC(C)[Mg]Cl.O=C(Cl)CCc1ccccc1>>CC(C)C(=O)CCc1ccccc1,Cl[Cu],C1CCOC1,,[Cl-].[Li+],,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(C2CCC3(CC2)OCCO3)c2ncnn12>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(C2CCC(=O)CC2)c2ncnn12,,CCOC(C)=O,,C1CCOC1,Cl,test
US20070299051A1,CN1CCNCC1.COC(=O)c1cc(C)c2c(c1)S(=O)(=O)Cc1cc(NC(=O)CCl)cc(Cl)c1O2>>COC(=O)c1cc(C)c2c(c1)S(=O)(=O)Cc1cc(NC(=O)CN3CCN(C)CC3)cc(Cl)c1O2,,CN(C)C=O,,,,test
US20090247507A1,COc1ccc(C=O)cc1.Nc1ncc(Br)c(N2CCN(Cc3ccccn3)CC2)c1[N+](=O)[O-]>>COc1ccc(-c2nc3c(N4CCN(Cc5ccccn5)CC4)c(Br)cnc3[nH]2)cc1,,CCO,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20060084651A1,CCn1c(-c2nc(Br)cnc2N)nc2cnccc21.CS(=O)(=O)c1cccc(B(O)O)c1>>CCn1c(-c2nc(-c3cccc(S(C)(=O)=O)c3)cnc2N)nc2cnccc21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090124802A1,Cc1cc(C)c(Oc2nc(Nc3ccc(C#N)cc3)nc3ccn(Cc4ccccc4)c23)c(C)c1>>Cc1cc(C)c(Oc2nc(Nc3ccc(C#N)cc3)nc3cc[nH]c23)c(C)c1,,Clc1ccccc1Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20070292352A1,Nc1ccc(S(=O)(=O)Nc2nccs2)cc1.O=C1CCC(=O)O1>>O=C(O)CCC(=O)Nc1ccc(S(=O)(=O)Nc2nccs2)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20020016347A1,Cc1ccccc1C(=O)c1ccc(N)cc1Cl.Clc1ncc(Br)c2ccccc12>>Cc1ccccc1C(=O)c1ccc(Nc2ncc(Br)c3ccccc23)cc1Cl,,C1COCCO1,,CC(C)(C)O[Na],,test
US20120208840A1,CC(C)(C)OC(=O)CC(C)(O)c1cccnc1NC(=O)C(C)(C)C>>Cc1cc(=O)[nH]c2ncccc12,,Cl,,,,test
US20110269712A1,CC(C)(C)OC(=O)N1CCC(O)CC1.CCOC(=O)c1c[nH]nn1>>CCOC(=O)c1cnn(C2CCN(C(=O)OC(C)(C)C)CC2)n1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140170067A1,CC(=O)OC(C)=O.CCOC(=O)C(N)C(=O)OCC>>CCOC(=O)C(NC(C)=O)C(=O)OCC,,ClCCl,,CCN(CC)CC,Cl,test
US20120101103A1,CC(=O)O.C[Si](C)(C)OC1(C#N)CCOc2cc(O)c(Cl)cc21>>O=C(O)C1CCOc2cc(O)c(Cl)cc21,,CCOC(C)=O,Cl,,,test
US06184398B2,CC[Si](CC)(CC)OC(C)(C)/C=C/CO[C@H](C)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>C[C@@H](OC/C=C/C(C)(C)O)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05610144,CC(C)(C)OC(=O)C1CCC(c2ccccc2)N1C(=O)CN.COC(=O)Cc1cccc(N=C=O)c1>>COC(=O)Cc1cccc(NC(=O)NCC(=O)N2C(C(=O)OC(C)(C)C)CCC2c2ccccc2)c1,,C1CCOC1,,[Br-].[K+],,test
US20060148858A1,CC(C)O.CCOc1cc(OCCCc2cn(-c3ccc(C(F)(F)F)cn3)nc2O)ccc1CCC(=O)OC>>CCOc1cc(OCCCc2cn(-c3ccc(C(F)(F)F)cn3)nc2OC(C)C)ccc1CCC(=O)O,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120214735A1,Nc1ncc(Br)s1.c1cn[nH]c1>>NC1N=CC(n2cccn2)S1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140135332A1,CCOC(=O)C(Oc1ccc(F)c(C(N)=O)c1F)c1nc(-c2ccc(Cl)cc2)cs1>>NC(=O)c1c(F)ccc(OC(CO)c2nc(-c3ccc(Cl)cc3)cs2)c1F,,CO,,[BH4-].[Na+],,test
US20080280974A1,Cc1cc2c(cc1O)C(C)(C)CC1(CC(C)(C)c3cc(O)c(C)cc3O1)O2.OCCCBr>>Cc1cc2c(cc1O)C(C)(C)CC1(CC(C)(C)c3cc(OCCCO)c(C)cc3O1)O2,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20080287394A1,CC(C)(C)OC(=O)NNCc1ccc(F)cc1.CN1CCn2cc(C(=O)Cl)c(OCc3ccccc3)c2C1=O>>CN1CCn2cc(C(=O)N(Cc3ccc(F)cc3)NC(=O)OC(C)(C)C)c(OCc3ccccc3)c2C1=O,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20130115194A1,C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1c1ccc(N)cn1.O=C(O)c1cc(Cl)c(Br)c(OC(F)(F)F)c1>>C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1c1ccc(NC(=O)c2cc(Cl)c(Br)c(OC(F)(F)F)c2)cn1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040087759A1,CC1(CBr)COC1.OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>CC1(COCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)COC1,,CN(C)C=O,,[H-].[Na+],,test
US20050020503A1,Cc1c(OC(C)(C)C)cccc1[N+](=O)[O-]>>Cc1c(N)cccc1OC(C)(C)C,[Pd],CCO,,,,test
US20060019991A1,NCCc1ccc(I)cc1.O=C1OC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1CCc1ccc(I)cc1,,CC(=O)O,,,,test
US05420343,CC(C)(C)c1ccc(CCO)c(C(C)(C)C)c1.O=S(Cl)Cl>>CC(C)(C)c1ccc(CCCl)c(C(C)(C)C)c1,,Cc1ccccc1,,,,test
US20020037900A1,Brc1ccc(Br)nc1.CC(C)(C)OC(=O)N1CCC(O)CC1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(Br)cn2)CC1,,CN1CCCC1=O,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20070054884A1,Clc1ccc(Oc2cc(Br)c(Cl)cc2OCc2ccccc2)c(Cl)c1.N#C[Cu]C#N>>N#Cc1cc(Oc2ccc(Cl)cc2Cl)c(OCc2ccccc2)cc1Cl,,CN(C)C=O,O,[C-]#N.[Na+],,test
US04100168,CC(C(=O)O)c1ccc2oc(Cc3ccc(Cl)c(Cl)c3)nc2c1>>CC(C(=O)O)c1ccc2oc(Cc3ccc(Cl)cc3)nc2c1,,CCO,,[Na+].[OH-],,test
US20010027196A1,CS(=O)c1nc(N)nc(-n2cccn2)c1C#N.NCc1ccc(C(F)(F)F)cc1>>N#Cc1c(NCc2ccc(C(F)(F)F)cc2)nc(N)nc1-n1cccn1,,COCCOC,,,,test
US20150284411A1,Nc1cnc(Cl)cc1N.S=C(n1ccnc1)n1ccnc1>>S=c1[nH]c2cnc(Cl)cc2[nH]1,,CN(C)C=O,,CCN(CC)CC,,test
US20110124637A1,CC(C)(C)OC(=O)N1CCC(Oc2ccccc2-c2nc3c(C(=O)O)cccc3[nH]2)CC1.Nc1nccs1>>O=C(Nc1nccs1)c1cccc2[nH]c(-c3ccccc3OC3CCNCC3)nc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080293770A1,O=C1CCOCC1.O=c1[nH]c2cc(F)c(Cl)cc2n1C1CCNCC1>>O=c1[nH]c2cc(F)c(Cl)cc2n1C1CCN(C2CCOCC2)CC1,,CO,,Cl,[BH3-]C#N.[Na+],test
US20100120739A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.CCC(=O)CBr>>CCC(=O)Cn1cc(B2OC(C)C(C)(C)O2)cn1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150299179A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N)ns2)cc1C#N.NS(N)(=O)=O>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4NS(N)(=O)=O)ns2)cc1C#N,,C1COCCO1,,Cl,,test
US20100256097A1,BrCc1cccc(Br)n1.CCOC(=O)CS>>CCOC(=O)CSCc1cccc(Br)n1,,C1CCOC1,O,[H-].[Na+],,test
US20100249407A1,Nc1cnc(Br)cn1.O=C(CBr)c1ccc(O)cc1>>Oc1ccc(-c2cn3cc(Br)ncc3n2)cc1,,CC#N,,,,test
US04882350,BrCc1ccccc1.CCCCOC1CCC(=O)N1>>CCCCOC1CCC(=O)N1Cc1ccccc1,,C1CCOC1,,[K+].[OH-],,test
US20060270690A1,CC(=O)c1cccc(N)c1.CCCS(=O)(=O)Cl>>CCCS(=O)(=O)Nc1cccc(C(C)=O)c1,,ClCCl,,O,c1ccncc1,test
US20100029948A1,CC(C#N)CCC#N.N>>Cc1ccc(N)nc1N,[Pd],,,,,test
US20020049217A1,Cn1cncc1C(C)(N)c1ccc(C#N)c(F)c1.O=S(=O)(NCCCBr)c1cccc(O)c1>>Cn1cncc1C(C)(NCCCNS(=O)(=O)c1cccc(O)c1)c1ccc(C#N)c(F)c1,,CC#N,,CCN(CC)CC,,test
US20160264598A1,COc1c(CC(NC(=O)CCNS(C)(=O)=O)B2OC3CC4CC(C4(C)C)C3(C)O2)cccc1C(=O)OC(C)(C)C>>CS(=O)(=O)NCCC(=O)NC1Cc2cccc(C(=O)O)c2OB1O,,ClCCl,,BrB(Br)Br,,test
US08283363B2,CC(C)(C)OC(=O)N(Cc1ccccc1)NC(=O)C(=O)C(Cc1ccccc1)NC(=O)[C@H]1CCC(=O)N1Cc1ccccc1.O=C(O)C(F)(F)F>>O=C(NNCc1ccccc1)C(=O)C(Cc1ccccc1)NC(=O)[C@H]1CCC(=O)N1Cc1ccccc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20150344408A1,CC(C)(C)[Si](C)(C)OCCc1ccc(O)cc1.CNCC[C@H](O)c1cccs1>>CNCC[C@@H](Oc1ccc(CCO[Si](C)(C)C(C)(C)C)cc1)c1cccs1,,Cc1ccccc1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030220361A1,CC(C)(C)OC(=O)NC1CCC(N)CC1.O=C(O)c1cc(F)cnc1Cl>>CC(C)(C)OC(=O)NC1CCC(NC(=O)c2cc(F)cnc2Cl)CC1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20110021506A1,CN.O=C(O)[C@@H]1CC[C@@H](Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)CC1>>CNC(=O)[C@@H]1CC[C@@H](Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)CC1,,C1CCOC1,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110312963A1,Cc1ccc(-n2nc(C(C)(C)C)cc2N)cc1.Nc1nccc(Oc2ccc(N)c3ccccc23)n1.O=C(n1ccnc1)n1ccnc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(N)n3)c3ccccc23)cc1,,ClCCl,,,,test
US20120015962A1,CCOC(=O)c1cnc2c(C(=O)Nc3cc4cccnc4cc3OC)csc2c1>>COc1cc2ncccc2cc1NC(=O)c1csc2cc(CO)cnc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06498165B1,C[C@H](Nc1nccc(-n2cnc3ccccc32)n1)c1cccc(N)c1.O=C(Cl)c1ccccc1>>C[C@H](Nc1nccc(-n2cnc3ccccc32)n1)c1cccc(NC(=O)c2ccccc2)c1,,ClCCl,,CCN(CC)CC,,test
US04478849,CC(=O)c1ccc(OCc2ccccc2)c(CO)c1.O=[Se]=O>>O=CC(=O)c1ccc(OCc2ccccc2)c(CO)c1,,C1COCCO1,O,,,test
US20160176848A1,CC(C)(C)OC(=O)N(CC[C@@H]1Cc2ccccc2CN1C(=O)c1cc2c(cc1-c1cc(C(=O)N(c3ccccc3)c3ccc(O[Si](C)(C)C(C)(C)C)cc3)c3n1CCCC3)OCO2)CC(F)F>>O=C(c1cc(-c2cc3c(cc2C(=O)N2Cc4ccccc4C[C@H]2CCNCC(F)F)OCO3)n2c1CCCC2)N(c1ccccc1)c1ccc(O)cc1,,C1COCCO1,CO,Cl,[K+].[OH-],test
US20070082913A1,COC(=O)c1ccc(Cl)nc1N.[Li]O>>Nc1nc(Cl)ccc1C(=O)[O-].[Li+],,CO,O,,,test
US20150210682A1,CCBr.CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(O)cc1CC2CC>>CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCC)cc1CC2CC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060079523A1,Cc1ccc(S(=O)c2ccc(C)cc2)cc1.O=C1CCC(=O)N1Br>>Cc1ccc(S(=O)c2ccc(CBr)cc2)cc1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20070027071A1,Brc1cccc2c1CN(Cc1ccccc1)C2.C=C[Sn](CCCC)(CCCC)CCCC>>C=Cc1cccc2c1CN(Cc1ccccc1)C2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20060281695A1,CCOCCl.O=S(=O)(Nc1cccc(Oc2ccc(Cl)cc2Cl)c1)C(F)(F)F>>CCOCN(c1cccc(Oc2ccc(Cl)cc2Cl)c1)S(=O)(=O)C(F)(F)F,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070093521A1,CCOc1cc(C=O)cc(OCC)c1Cl.OCc1nccc2nc(NC3CCNCC3)oc12>>CCOc1cc(CN2CCC(Nc3nc4ccnc(CO)c4o3)CC2)cc(OCC)c1Cl,,CC(=O)O,CCO,CCN(C(C)C)C(C)C,[BH3-]C#N.[Na+],test
US06100416,CC1=Cc2c(C)ccc(C)c2C1.[Li]CCCC>>[Li]C1C(C)=Cc2c(C)ccc(C)c21,,C1CCOC1,,CCCCCC,,test
US20060004017A1,COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OC[C@@H](CN1CCCC1)OC(C)=O>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OC[C@H](O)CN1CCCC1,,CO,,N,,test
US20130331409A1,C[Si](C)(C)CCOCn1c(Cl)nc2ccccc21.Oc1ccc(C2CCCn3ccnc32)cc1>>C[Si](C)(C)CCOCn1c(Oc2ccc(C3CCCn4ccnc43)cc2)nc2ccccc21,,CN(C)C=O,,O,[H-].[Na+],test
US20030087833A1,CCOC(=O)CBr.CCOC(=O)CCNC(=O)[C@@H](N)Cc1ccccc1>>CCOC(=O)CCNC(=O)[C@H](Cc1ccccc1)NCC(=O)OCC,,Cc1ccccc1,,CCN(CC)CC,,test
US20040157804A1,Cc1ccnc2c(OC(=O)c3ccccc3)c3c(cc12)CN(CC1CC=CC1)C3=O.O=C1CCC(=O)N1Br>>O=C(Oc1c2c(cc3c(CBr)ccnc13)CN(CC1CC=CC1)C2=O)c1ccccc1,,CCOC(C)=O,,,,test
US20100105700A1,CC(C)(C)OC(=O)N1CC2C3CCC(=O)C3(C)CCC2C2(C)CCC(=O)C=C12>>C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CCC2=O,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20080039444A1,CCOC(=O)c1ccc2c(c1)CCN(C1CCC1)CC2>>O=C(O)c1ccc2c(c1)CCN(C1CCC1)CC2,,CCO,,Cl,[Na+].[OH-],test
US20150175604A1,CI.Cc1nnc2ccc3c(cc(-c4ccn[nH]4)n3Cc3cc(Cl)cc(CO[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)c3)n12>>Cc1nnc2ccc3c(cc(-c4ccn(C)n4)n3Cc3cc(Cl)cc(CO[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)c3)n12,,CN(C)C=O,,[H-].[Na+],,test
US20130172341A1,COC(=O)C1CCC2CCC1N2C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1C2CCC(C(=O)O)C1CC2,,CO,O,Cl,[K+].[OH-],test
US20060252812A1,C1CCOC1.CO.O=C1Nc2ccccc2C12COc1ccc(O)cc12>>COc1ccc2c(c1)C1(CO2)C(=O)N(C)c2ccccc21,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130196002A1,COc1ccc(COc2cnc(-c3cccc(O)c3)n(C)c2=O)cc1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1ccc(COc2cnc(-c3cccc(OS(=O)(=O)C(F)(F)F)c3)n(C)c2=O)cc1,,c1ccncc1,,O,,test
US20090181996A1,COc1c(N2CCC(C(=O)O)CC2)c(F)cc2c(=O)c(C(=O)NCc3ccc(OC(F)(F)F)cc3C)cn(CC(F)(F)F)c12.OCCNCCO>>COc1c(N2CCC(C(=O)O)CC2)c(F)cc2c(=O)c(C(=O)NCc3ccc(OC(F)(F)F)cc3C)cn(CC(F)(F)F)c12.OCCNCCO,,O,,CC#N,,test
US20150210688A1,COC(=O)c1cc(I)[nH]n1.N>>NC(=O)c1cc(I)[nH]n1,,CO,,,,test
US20160145267A1,CCOc1cc(F)c(Cn2nc(-c3nc(N)c(/N=N/c4ccccc4)c(N)n3)c(C)c2C2CC2)c(F)c1>>CCOc1cc(F)c(Cn2nc(-c3nc(N)c(N)c(N)n3)c(C)c2C2CC2)c(F)c1,[Pd],CN(C)C=O,,[H][H],,test
US20140171403A1,CN(CCC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1)C(=O)OC(C)(C)C>>CNCCC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05710162,CCOC(=O)c1c(-c2ccccc2)c2ccc(C)cc2[nH]c1=O>>Cc1ccc2c3c(c(=O)[nH]c2c1)C(=O)c1ccccc1-3,,O=S(=O)(O)O,,,,test
US20100048610A1,CCOC(=O)c1ccc(O)nc1.[I-]>>CCOC(=O)c1cnc(O)c(I)c1,,c1ccncc1,,O,,test
US20150051214A1,CC(C)C(O)c1cc2cc(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)c(S(C)(=O)=O)cc2n1S(C)(=O)=O>>CC(C)C(=O)c1cc2cc(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)c(S(C)(=O)=O)cc2n1S(C)(=O)=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05126336,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(/C=C\CCl)CS[C@H]12>>CC(C)(C)OC(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(/C=C\CCl)CS[C@H]12,,ClCCl,,Cl,O=C([O-])O.[Na+],test
US05650415,CCOC(=O)c1cnc2ccc(C(F)(F)F)cc2c1Cl.FC(F)(F)c1cccc(S)c1>>CCOC(=O)c1cnc2ccc(C(F)(F)F)cc2c1Sc1cccc(C(F)(F)F)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US04411839,Cc1cccc(C)c1NNC(N)=O.N#CCC(=O)O>>Cc1cccc(C)c1N(NC(N)=O)C(=O)CC#N,,CCOCC,,CC(=O)OC(C)=O,,test
US20130324528A1,CC(C)(C)OC(=O)N1CCC(Br)CC1.Ic1ccnc2cn[nH]c12>>CC(C)(C)OC(=O)N1CCC(n2cc3nccc(I)c3n2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20100179216A1,O=C1CCC(=O)N1Br.OCCCC1CCCCC1>>BrCCCC1CCCCC1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070244095A1,Cc1cc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H]2CCCN(C(=O)OC(C)(C)C)c3cc(C(F)(F)F)c(C)cc32)on1>>Cc1cc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H]2CCCNc3cc(C(F)(F)F)c(C)cc32)on1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20160002224A1,CC(=O)OCC1(c2ccc(-c3cc4c(cc3Cl)NC(=O)C4)cc2)CC1.O=P(Cl)(Cl)Cl>>CC(=O)OCC1(c2ccc(-c3cc4cc(Cl)[nH]c4cc3Cl)cc2)CC1,,ClCCCl,,c1c[nH]cn1,,test
US20060235033A1,CC(N)c1ccc(F)cc1.COc1cc2c(Oc3ccc(N)c(F)c3)ccnc2cc1OCCCN1CCOCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2c(Oc3ccc(NC(=O)NC(C)c4ccc(F)cc4)c(F)c3)ccnc2cc1OCCCN1CCOCC1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20150274705A1,C1CCOC1.O=C1CCC2(CC1)OCCO2>>CCOC(=O)C=C1CCC2(CC1)OCCO2,,C1CCOC1,,[H-].[Na+],,test
US20040082780A1,CC(=O)OC(C)=O.Nc1cnc2cccc(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2n1>>CC(=O)Nc1cnc2cccc(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2n1,,Cc1ccccc1,,,,test
US20110144105A1,CS(=O)(=O)c1ccc(B(O)O)cc1.Cc1ccc(S(=O)(=O)OC(=CC2CCCC2)c2cc3cc(C)cnc3n2S(=O)(=O)c2ccccc2)cc1>>Cc1cnc2c(c1)cc(C(=CC1CCCC1)c1ccc(S(C)(=O)=O)cc1)n2S(=O)(=O)c1ccccc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US20080300242A1,COc1cc(C2CCN(CCF)CC2)ccc1N.COc1ccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)cc1C(=O)Nc1c(F)cccc1F>>COc1cc(C2CCN(CCF)CC2)ccc1Nc1nccc(-c2c(-c3ccc(OC)c(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20060116376A1,NNc1ccc(Cl)cc1.O=c1[nH]c2ccccc2c(=O)o1>>Nc1ccccc1C(=O)NNc1ccc(Cl)cc1,,CCO,,CCN(C(C)C)C(C)C,Cl,test
US20130190312A1,CC(=O)c1c(C)cc(O)cc1C.Clc1ncccn1>>CC(=O)c1c(C)cc(Oc2ncccn2)cc1C,[Cu],CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04078071,ClCc1ccc(Cl)cc1Cl.OC(/C=C/c1ccccc1)Cn1ccnc1>>Clc1ccc(COC(/C=C/c2ccccc2)Cn2ccnc2)c(Cl)c1,,C1CCOC1,,[H-].[Na+],,test
US20030134853A1,CC(C)(C)[Si](C)(C)Oc1ccc(-c2nc3cc(C#N)ccc3n2C2CCCCC2)cc1.C[Si](C)(C)N=[N+]=[N-]>>CC(C)(C)[Si](C)(C)Oc1ccc(-c2nc3cc(-c4nnn[nH]4)ccc3n2C2CCCCC2)cc1,,CCOC(C)=O,Cc1ccccc1,C[Al](C)C,Cl,test
US20090082423A1,NCC1CCOCC1.O=C=NC12CC3CC(CC(C3)C1)C2>>O=C(NCC1CCOCC1)NC12CC3CC(CC(C3)C1)C2,,C1CCOC1,,,,test
US20110245220A1,CC(C)(C)[Si](C)(C)Cl.Oc1c(F)cc(Br)cc1F>>CC(C)(C)[Si](C)(C)Oc1c(F)cc(Br)cc1F,,ClCCl,O,c1c[nH]cn1,,test
US20120133273A1,CCOC(C)=N.O=C(Cl)c1ccc2ccccc2c1>>CCOC(C)=NC(=O)c1ccc2ccccc2c1,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US20100112090A1,COc1cc(Cl)c([N+](=O)[O-])cc1O.COc1cccc(F)c1CBr>>COc1cc(Cl)c([N+](=O)[O-])cc1OCc1c(F)cccc1OC,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090221567A1,Cc1ccccc1C(=O)O.O=C1CO[C@H]2CCCC[C@@H]2N1C1CCN(C2CCNCC2)CC1>>Cc1ccccc1C(=O)N1CCC(N2CCC(N3C(=O)CO[C@H]4CCCC[C@@H]43)CC2)CC1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05977139,C[Si](C)(C)CCO.O=C(Cl)CCl>>C[Si](C)(C)CCOC(=O)CCl,,ClCCl,,CCN(CC)CC,,test
US05665754,COc1ccc(/C=C/C(=O)N(C)OC)cc1OC1CCCC1.[Li]C>>COc1ccc(/C=C/C(C)=O)cc1OC1CCCC1,,C1CCOC1,CCOCC,,,test
US20090036450A1,CCOC(=O)c1nc(C)c(CCl)s1.[N-]=[N+]=[N-]>>CCOC(=O)c1nc(C)c(CN=[N+]=[N-])s1,,CN(C)C=O,,O,,test
US20090156512A1,CCC[C@@H]1C[C@@H](C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)N(C)C1.C[Si](C)(C)Cl.C[Si](C)(C)N[Si](C)(C)C>>CCC[C@@H]1C[C@@H](C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H]2O[Si](C)(C)C)N(C)C1,,c1ccncc1,,,,test
US20090281075A1,CC(C)(C)OC(=O)N1CC[C@@H](CNc2ncc([N+](=O)[O-])c(NCc3cccc(I)c3)n2)C1>>CC(C)(C)OC(=O)N1CC[C@@H](CNc2ncc(N)c(NCc3cccc(I)c3)n2)C1,[Pt],CO,,,,test
US20130109679A1,CC1CCN(C(=O)OC(C)(C)C)S(=O)(=O)O1.CCOC(=O)c1ccc2cc(C(=O)OCC)[nH]c2c1>>CCOC(=O)c1ccc2cc(C(=O)OCC)n(C(C)CCNC(=O)OC(C)(C)C)c2c1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20140094495A1,CC(CO)(CF)NC(=O)OCc1ccccc1>>CC1(CF)COC(=O)N1,,C1CCOC1,,CC(=O)O,[H-].[Na+],test
US20120270943A1,N[C@H](CC(=O)O)C(=O)O>>N[C@H](CC(=O)O)C(=O)O,,Cl,,,,test
US20130005760A1,Cc1noc(C)c1-c1ccc2c(=O)cc(C)n(-c3ccc(F)cc3F)c2c1.O=[Se]=O>>Cc1noc(C)c1-c1ccc2c(=O)cc(C=O)n(-c3ccc(F)cc3F)c2c1,,C1COCCO1,,CCOC(C)=O,O=C([O-])O.[Na+],test
US20030139449A1,COc1ccccc1C1CCN(C[C@H](N)CC2CCCCC2)CC1.ClCCl.O=C(Cl)C1CCCCC1>>COc1ccccc1C1CCN(C[C@@H](CC2CCCCC2)NC(=O)C2CCCCC2)CC1.Cl,,ClCCl,O,O=C([O-])[O-].[K+].[K+],,test
US20050002864A1,CCOC(=O)CCCCCCBr.Oc1c(I)cc(I)cc1I>>CCOC(=O)CCCCCCOc1c(I)cc(I)cc1I,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080280875A1,COC(=O)c1cc(Oc2ccc(C(=O)OC(C)(C)C)nc2)c2c(c1)OC(C)(C)C2>>COC(=O)c1cc(Oc2ccc(C(=O)O)nc2)c2c(c1)OC(C)(C)C2,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100022514A1,COC(=O)/C=C/c1ccc2c(c1)CCN(C(=O)OC(C)(C)C)CC2>>COC(=O)/C=C/c1ccc2c(c1)CCNCC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020019554A1,COc1ccc(C(=O)O)cc1.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3.SCc1ccccc1>>COc1ccc(C(=S)SCc2ccccc2)cc1,,Cc1ccccc1,,,,test
US20090170920A1,CON(C)C(=O)c1ccc(Br)cc1C.C[Mg]Cl>>CC(=O)c1ccc(Br)cc1C,,C1CCOC1,,[Cl-].[NH4+],,test
US20060154974A1,CC(C)(C)CC(=O)Cl.Cc1cc(C(=O)Nc2nccs2)cc(Cl)c1N>>Cc1cc(C(=O)Nc2nccs2)cc(Cl)c1NC(=O)CC(C)(C)C,,ClCCCl,,c1ccncc1,,test
US07078414B2,O=C(Cl)C(=O)Cl.O=C(O)c1ccn(-c2nccc3ccccc23)c1>>Cl.O=C(Cl)c1ccn(-c2nccc3ccccc23)c1,,ClCCl,,,,test
US20090209522A1,COc1nc(NCCN(C(=O)OC(C)(C)C)C(C)C)nc(OC)c1NC(=O)c1csc(Oc2ccccc2C(C)(C)C)n1>>COc1nc(NCCNC(C)C)nc(OC)c1NC(=O)c1csc(Oc2ccccc2C(C)(C)C)n1,,[NH4+],[OH-],CC#N,,test
US04540699,CCCCn1ccc(CCC(=O)OCC)cc1=O.CCOC=O>>CCCCn1ccc(CC(C=O)C(=O)OCC)cc1=O,,COCCOC,,[H-].[Na+],,test
US20110098275A1,C#Cc1ccc(N)nc1.Cc1nccc(Cl)c1I>>Cc1nccc(Cl)c1C#Cc1ccc(N)nc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,CCN(CC)CC,,test
US20080009530A1,CCOC(=O)CCc1cc(OCC(=O)OC(C)(C)C)nn1Cc1ccc(Cl)cc1Cl>>CCOC(=O)CCc1cc(OCC(=O)O)nn1Cc1ccc(Cl)cc1Cl,,O=C(O)C(F)(F)F,,,,test
US20030036655A1,CC(C)Oc1ccc(C(=O)c2ccc([N+](=O)[O-])cc2)cc1>>CC(C)Oc1ccc(Cc2ccc(N)cc2)cc1,[Pd],CCO,,Cl,,test
US20070088001A1,CCC[C@H](NC(=O)[C@H](C[Si](C)(C)C)NC(=O)N1CCOCC1)C(O)c1nc2ccccc2o1>>CCC[C@H](NC(=O)[C@H](C[Si](C)(C)C)NC(=O)N1CCOCC1)C(=O)c1nc2ccccc2o1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20050143422A1,CCOC(=O)c1oc2ccc(Cl)c(O)c2c1C.CI>>CCOC(=O)c1oc2ccc(Cl)c(OC)c2c1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040092533A1,Brc1cccc(Br)n1.CCCC[Sn](CCCC)(CCCC)c1ccccn1>>Brc1cccc(-c2ccccn2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,,,test
US20120252807A1,CC(C)(C)OC(=O)N1CCC(C(=O)NCc2ccccc2)CC1.Cl>>Cl.O=C(NCc1ccccc1)C1CCNCC1,,C1CCOC1,,C1COCCO1,,test
US20160152626A1,CCOC(=O)C(O)=C1COc2cc(OC)c(Br)cc2C1=O.NNc1cccs1>>CCOC(=O)c1nn(-c2cccs2)c2c1COc1cc(OC)c(Br)cc1-2,,CC(=O)O,CCO,Cl,,test
US20120232051A1,Cc1ccccc1B(O)O.N#CCNc1cnccc1I>>Cc1ccccc1-c1ccncc1NCC#N,,CCCCCCC,CCOC(C)=O,,,test
US20080108651A1,CCOC(CCN)OCC.CSC(Nc1ccsc1)=C1C(=O)OC(C)(C)OC1=O>>CCOC(CCNC(Nc1ccsc1)=C1C(=O)OC(C)(C)OC1=O)OCC,,CO,ClCCl,,,test
US20120295884A1,CC(C)(C)OC(=O)CBr.COc1ccc(CNc2ccc3c(C(C)=O)c[nH]c3n2)cc1>>COc1ccc(CNc2ccc3c(C(C)=O)cn(CC(=O)OC(C)(C)C)c3n2)cc1,,C1CCOC1,CC#N,O=C([O-])[O-].[K+].[K+],,test
US04587047,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@H]1CNC1=O>>CC(C)(C)OC(=O)N[C@H]1CNC1=O,,C1CCOC1,CC(C)(C)O,CCN(CC)CC,,test
US20140296243A1,BrBr.CCOC(=O)C=NNc1ccc(Cl)nn1>>CCOC(=O)C(Br)=NNc1ccc(Cl)nn1,,CC(=O)O,O,CC(=O)[O-].[Na+],,test
US20070208059A1,CC(C)CCS(=O)(=O)Cl.Cc1c(C(=O)Nc2ccc(C(F)(F)F)cn2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(O)cc1>>Cc1c(C(=O)Nc2ccc(C(F)(F)F)cn2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(C)C)cc1,,ClCCl,,CCN(CC)CC,O,test
US20060252790A1,CCn1ncc2c(NC3CCOCC3)c(C(N)=O)cnc21>>CCn1ncc2c(NC3CCOCC3)c(C#N)cnc21,,C1CCOC1,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US20070015773A1,C=CS(=O)(=O)CC.CC(N)c1nc2ccc(F)cn2c(=O)c1Br>>CCS(=O)(=O)CCNC(C)c1nc2ccc(F)cn2c(=O)c1Br,,CO,,CCN(CC)CC,,test
US06190650B1,O=Cc1ccc(C(=O)O)c(O)c1.[BH3-]C#N>>NCc1ccc(C(=O)O)c(O)c1,,O,,O=C([O-])O.[Na+],,test
US05599832,CCOC(=O)C(F)(F)F.COc1ccc(N[Si](C)(C)C)c(C)c1>>COc1ccc2[nH]c(C(F)(F)F)cc2c1,,C1CCCCC1,,CN(C)CCN(C)C,[Li]CCCC,test
US20110281841A1,CCOC(=O)COc1c(OC)cccc1OC.O=[N+]([O-])O>>CCOC(=O)COc1c(OC)cc([N+](=O)[O-])cc1OC,,ClCCl,,,,test
US20100286112A1,CC(C)c1noc(N2CCC([C@H](C)CCOc3ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)N4CCC[C@H]4C#N)c(F)c3)CC2)n1>>CC(C)c1noc(N2CCC([C@H](C)CCOc3ccc(C[C@H](N)C(=O)N4CCC[C@H]4C#N)c(F)c3)CC2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100009991A1,CCOC(=O)COc1cccc(OCCCOC2CCCCO2)c1>>CCOC(=O)COc1cccc(OCCCO)c1,,CCO,,Cl,O=C([O-])O.[Na+],test
US20040077622A1,CC1(C)Cc2cc(CO)nn2C1>>CC1(C)Cc2cc(C=O)nn2C1,O=[Mn]=O,ClC(Cl)Cl,,,,test
US04886733,O=C1CCCc2c1ccc1ccccc21>>Oc1cccc2ccc3ccccc3c12,,ClC(Cl)(Cl)Cl,,O=C1CCC(=O)N1Br,,test
US20110257174A1,Nc1cccc2c(=O)cc(-c3cccc(C(F)(F)F)c3)oc12.O=C(O)c1cscn1>>O=C(Nc1cccc2c(=O)cc(-c3cccc(C(F)(F)F)c3)oc12)c1cscn1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060052392A1,C=C(C)C(=C)C.O=C1C=CC(=O)O1>>CC1=C(C)CC2C(=O)OC(=O)C2C1,,c1ccccc1,,,,test
US05849930,CC(C)=CCC/C(C)=C/COc1ccc(C(=O)O)cc1.O=C(n1ccnc1)n1ccnc1>>CC(C)=CCC/C(C)=C/COc1ccc(C(=O)c2ncc[nH]2)cc1,,O,,,,test
US20070066583A1,COc1cc(C2(O)CCN(C(=O)OC(C)(C)C)CC2)ccc1Cl.Cl>>COc1cc(C2(O)CCNCC2)ccc1Cl.Cl,,CCOCC,CO,,,test
US05565413,CCOc1c(S(C)(=O)=O)ccc(C(=O)c2c(Cl)ccnc2Cl)c1C.OCc1ccccc1.c1ccc(COCc2ccccc2)cc1>>CCOc1c(S(C)(=O)=O)ccc(C(=O)c2c(OCc3ccccc3)ccnc2OCc2ccccc2)c1C,,C1CCOC1,,[H-].[Na+],,test
US20150065507A1,Cc1nc(N2CCOC2=O)ccc1[N+](=O)[O-]>>Cc1nc(N2CCOC2=O)ccc1N,[Pd],,,,,test
US07547718B2,Cc1cccc([C@H](C)c2ncc[nH]2)c1C.O=C(Cl)OCc1ccccc1>>Cc1cccc([C@H](C)c2nccn2C(=O)OCc2ccccc2)c1C,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20100278733A1,CC(=O)c1ccc(Br)s1.O=Cc1ccc([N+](=O)[O-])cc1>>O=C(C=Cc1ccc([N+](=O)[O-])cc1)c1ccc(Br)s1,,CCO,,[K+].[OH-],,test
US06114334,C=O.CC1N=C(c2ccccc2)NC1=O.c1cc2c(c(N3CCNCC3)c1)OCCO2>>CC1(CN2CCN(c3cccc4c3OCCO4)CC2)N=C(c2ccccc2)NC1=O,,,,,,test
US20130116235A1,O=Cc1c(Cl)ccnc1N1CCc2c(cc3n2CCCC3)C1=O>>O=C1c2cc3n(c2CCN1c1nccc(Cl)c1CO)CCCC3,,CO,,[BH4-].[Na+],,test
US20090005397A1,CCCOc1ccccc1C1(O)C(=O)Nc2ccc(Cl)cc21.N>>COc1ccccc1C1(N)C(=O)Nc2ccc(Cl)cc21,,ClCCl,,CCO,O,test
US20040157836A1,COC(=O)c1c(N)ccc2ncccc12.O=S(=O)(Cl)c1ccccc1>>COC(=O)c1c(NS(=O)(=O)c2ccccc2)ccc2ncccc12,,c1ccncc1,,,,test
US04766152,CCOC(COc1ccc(Oc2ccccc2)cc1)OCC>>O=CCOc1ccc(Oc2ccccc2)cc1,,C1CCOC1,,Cl,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2c(OC)cccc23)cc1.Nc1ccccc1>>COc1cccc2c1nc(Nc1ccccc1)c1n[nH]cc12,C1COCCO1,CO,,Cl,,test
US20050153972A1,C#CC(=O)O[Si](C)(C)C.COC(=O)c1ccc(C)c(N=[N+]=[N-])c1>>COC(=O)c1ccc(C)c(-n2cc(C(=O)O)nn2)c1,,O,,CO,,test
US05244892,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CSc1cc(=O)c2cc(O)c(O)cc2s1>>CSc1cc(=O)c2cc(OC(=O)OC(C)(C)C)c(OC(=O)OC(C)(C)C)cc2s1,CN(C)c1ccncc1,ClCCl,,,,test
US06162811,Cc1c2ccnc(C(=O)NCCN(C)C)c2cc2c3cc(OC(=O)CCCCC(=O)OCc4ccccc4)ccc3n(C)c12>>Cc1c2ccnc(C(=O)NCCN(C)C)c2cc2c3cc(OC(=O)CCCCC(=O)O)ccc3n(C)c12,,CO,,[H][H],,test
US20050245586A1,C(#CC1CCNCC1)c1ccccc1.O=C1NC(=O)c2c(CCBr)cccc21>>NCCN1CCC(C#Cc2ccccc2)CC1,,CC#N,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20050096380A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.CCOc1cc2c(cc1Br)C(C(C)C)=CCC2(C)C>>CCOc1cc2c(cc1C(C)=O)C(C(C)C)=CCC2(C)C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,O,,,test
US05373015,CCc1cc2[nH]c(=O)ccc2c(CC)n1>>CCc1cc2c(c(CC)n1)CCC(=O)N2,[Pd],CCO,,,,test
US20070027178A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(Cl)c2c1N[C@@H]1CCNC[C@H]21>>Cc1ccc(Cl)c2c1N[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@H]21,,C1COCCO1,,[Na+].[OH-],,test
US20120232052A1,COC(=O)c1ccc2[nH]ccc2c1.COCCBr>>COCCn1ccc2cc(C(=O)OC)ccc21,,O,,[H-].[Na+],,test
US20140038926A1,COC(=O)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(C(=O)OC(C)(C)C)C2.C[Si](C)(C)c1nc(Br)cs1>>CC(C)(C)OC(=O)N1CCC2=Cc3c(cnn3-c3ccc(F)cc3)C[C@]2(C(=O)c2csc([Si](C)(C)C)n2)C1,,CCOCC,,O,[Li]CCCC,test
US04183932,COC(CN)OC.Clc1ccc2nc(Cl)nc(-c3ccccc3)c2c1>>COC(CNc1nc(-c2ccccc2)c2cc(Cl)ccc2n1)OC,,CS(C)=O,,CCCCCC,,test
US03950528,CCOC(=O)C=C(N)OCC.NNCc1cc(Cl)ccc1F>>Nc1cc(=O)n(Cc2cc(Cl)ccc2F)[nH]1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100120785A1,CC(C)(C)OC(=O)N1CCN(c2nccnc2Cl)CC1.COCc1ccc(B(O)O)cc1>>COCc1ccc(-c2nccnc2N2CCN(C(=O)OC(C)(C)C)CC2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(=O)N(C)C,,O,O=C([O-])[O-].[K+].[K+],test
US20060115425A1,CC(O)C(Cc1ccc(Cl)cc1)c1cccc(C#N)c1.CS(=O)(=O)Cl>>CC(OS(C)(=O)=O)C(Cc1ccc(Cl)cc1)c1cccc(C#N)c1,,Cc1ccccc1,,CCN(CC)CC,,test
US20120184539A1,O=C(CCl)NC(CO)(CO)c1cc(Br)cnc1Cl>>O=C1COCC(CO)(c2cc(Br)cnc2Cl)N1,,CC(C)(C)O,,O,CC(C)(C)[O-].[K+],test
US20140221344A1,Cc1ccc(-c2ncccc2F)nn1.O=c1n(Cl)c(=O)n(Cl)c(=O)n1Cl>>Fc1cccnc1-c1ccc(CCl)nn1,,ClCCCl,,,,test
US20120202832A1,COc1ccc(CNc2cc3c(Nc4ccc5c(cnn5Cc5cccc(F)c5)c4)ncnc3cn2)cc1>>Nc1cc2c(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)ncnc2cn1,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US05681858,C#C[C@@H]1C[C@@H](Oc2ccc(OC)cc2)C1.CC=O>>COc1ccc(O[C@@H]2C[C@@H](C#CC(C)O)C2)cc1,,C1CCOC1,,[Li]CCCC,,test
US07179823B1,CCOC(=O)CCc1c[nH]nc1OCC.COc1cc(CCl)ccc1OCc1ccccc1>>CCOC(=O)CCc1cn(Cc2ccc(OCc3ccccc3)c(OC)c2)nc1OCC,,O,,CN(C)C=O,[H-].[Na+],test
US20090247526A1,CCOC(=O)c1cnc(C)c(Oc2cc(Nc3nc(C4CCN(C(=O)OC(C)(C)C)CC4)ns3)ncc2Br)c1C>>Cc1ncc(C(=O)O)c(C)c1Oc1cc(Nc2nc(C3CCN(C(=O)OC(C)(C)C)CC3)ns2)ncc1Br,,CCO,,[Na+].[OH-],,test
US04914097,CC1CC(C)(C)c2cccc(N)c21.O=C(O)c1nccnc1O.O=P(Cl)(Cl)Cl>>CC1CC(C)(C)c2cccc(NC(=O)c3nccnc3Cl)c21,c1ccncc1,CCOC(C)=O,,CCN(CC)CC,,test
US20120295874A1,CC(C)(C)OC(=O)NCc1ccc(C(=O)NCc2ccc(OCCC(=O)N3CC(=O)[C@H](O[Si](C)(C)C(C)(C)C)C3)cc2)cc1.Cl>>Cl.NCc1ccc(C(=O)NCc2ccc(OCCC(=O)N3CC(=O)[C@H](O)C3)cc2)cc1,,C1COCCO1,ClCCl,,,test
US20080280891A1,CO.Cc1cc(C(=O)c2cc(Br)cc(NS(C)(=O)=O)c2)cc(Cl)n1>>COc1cc(C(=O)c2cc(Br)cc(NS(C)(=O)=O)c2)cc(C)n1,,C1COCCO1,CO,Cl,C[O-].[Na+],test
US20070299066A1,CS(=O)(=O)CCN.CS(=O)(=O)OCCn1cc2c(ccc3c2sc2ncnc(Nc4ccc(F)c(Cl)c4)c23)n1>>CS(=O)(=O)CCNCCn1cc2c(ccc3c2sc2ncnc(Nc4ccc(F)c(Cl)c4)c23)n1,,CN(C)C=O,CO,CCN(C(C)C)C(C)C,,test
US20130096118A1,O=[N+]([O-])/C=C/c1ccccc1F.c1cc2ccc(N3CCOCC3)cc2[nH]1>>O=[N+]([O-])CC(c1ccccc1F)c1c[nH]c2cc(N3CCOCC3)ccc12,,Cc1ccccc1,,,,test
US20120157476A1,CON.O=C(NCC(=O)C(F)(F)F)c1cnc(OCC(F)(F)F)c(-c2ccc(Cl)c(Cl)c2)c1>>CO/N=C(/CNC(=O)c1cnc(OCC(F)(F)F)c(-c2ccc(Cl)c(Cl)c2)c1)C(F)(F)F,,CCO,O,Cl,,test
US20080032970A1,CC(Br)C(N)=O.Sc1cccc(Br)c1>>CC(Sc1cccc(Br)c1)C(N)=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080171878A1,CCOC=C(C(=O)OCC)C(=O)OCC.N#Cc1ccc(NC(=N)N)cc1>>N#Cc1ccc(Nc2nc(=O)cc[nH]2)cc1,,CN1CCCC1=O,,O,CC(=O)[O-].[Na+],test
US20030236287A1,COc1cc(OC)c(C(F)(F)F)cc1[N+](=O)[O-]>>COc1cc(OC)c(C(F)(F)F)cc1N,[Pd],CCO,CCOC(C)=O,,,test
US07005440B1,O=S(Cl)Cl.OCc1cccc(OCc2ccc3ccccc3n2)c1>>Cl.ClCc1cccc(OCc2ccc3ccccc3n2)c1,,ClCCl,,,,test
US20160168156A1,CC(C)(C)OC(=O)N1CCC(C(=O)NN)CC1.O=C(O)c1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12>>CC(C)(C)OC(=O)N1CCC(C(=O)NNC(=O)c2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100069460A1,COc1ccc(Br)cc1.Cc1cc(OCc2ccccc2)c(C2(O)S[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1C=O>>COc1ccc(C(O)c2cc(C3(O)S[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)c(OCc3ccccc3)cc2C)cc1,,C1CCOC1,O,CCCCCC,[Li]CCCC,test
US20090093454A1,CC(C)(C)OC(=O)NC1CCNCC1.Fc1cccc2nc(CN3CCC[C@H]4CCc5cccnc5[C@H]43)cn12>>CC(C)(C)OC(=O)NC1CCN(c2cccc3nc(CN4CCC[C@H]5CCc6cccnc6[C@H]54)cn23)CC1,,CN1CCCC1=O,,O,,test
US20120046268A1,O=C(Nc1cncc(-c2ccc(C(F)(F)F)cc2)c1)c1ccccc1>>O=C(NC1CNCC(c2ccc(C(F)(F)F)cc2)C1)c1ccccc1,,CC(=O)O,,,,test
US20130102584A1,COC(=O)c1ccc(F)c([N+](=O)[O-])c1.Nc1ccc(F)cc1>>COC(=O)c1ccc(Nc2ccc(F)cc2)c([N+](=O)[O-])c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20100249124A1,CC(c1cc(OS(=O)(=O)C(F)(F)F)ccc1Cl)C(O)(c1ccc2c(c1)N(C)C(=O)CO2)C(F)(F)F.O=C(O)c1ccc(B(O)O)cc1>>CC(c1cc(-c2ccc(C(=O)O)cc2)ccc1Cl)C(O)(c1ccc2c(c1)N(C)C(=O)CO2)C(F)(F)F,,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20090124666A1,CCc1ncoc1-c1ccc(Br)cn1.ClC(Cl)(Cl)C(Cl)(Cl)Cl>>CCc1nc(Cl)oc1-c1ccc(Br)cn1,,C1CCOC1,O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20090099156A1,CCN1CCC[C@@H](CN2CCN(C(=O)OCc3ccccc3)CC2)C1>>CCN1CCC[C@@H](CN2CCNCC2)C1,[Pd],CCO,,,,test
US20160244415A1,Cc1c(Cn2c(=O)c(C(N)=NO)cn(-c3ccc(N4CCOC4=O)cc3)c2=O)cccc1C(F)(F)F.S=C(n1ccnc1)n1ccnc1>>Cc1c(Cn2c(=O)c(-c3nsc(=O)[nH]3)cn(-c3ccc(N4CCOC4=O)cc3)c2=O)cccc1C(F)(F)F,,O,,C1CCOC1,Cl,test
US05998433,CN(Cc1cc2c(o1)CN(C(=O)c1ccc(C(=O)c3ccccc3)cc1)CC2)C(=O)OC(C)(C)C.Cl>>CNCc1cc2c(o1)CN(C(=O)c1ccc(C(=O)c3ccccc3)cc1)CC2.Cl,,CO,,,,test
US20110294807A1,Cc1cc(C=O)ccc1OCCO.Nc1ccccc1C(=O)Nc1ccc(Br)cc1>>Cc1cc(-c2nc3ccccc3c(=O)n2-c2ccc(Br)cc2)ccc1OCCO,,CCO,,,,test
US20120329649A1,NN.O=C1NC(O)c2cc(Br)ccc21>>O=c1[nH]ncc2cc(Br)ccc12,,O,,,,test
US20040116435A1,Cc1cc2cccc(O)c2[nH]1.O=[N+]([O-])c1cccc(S(=O)(=O)C[C@@H]2CO2)c1>>Cc1cc2cccc(OC[C@@H]3CO3)c2[nH]1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060211678A1,CC(C)(C)OC(=O)N1CC=C(c2cc3c(Cl)ncnc3[nH]2)CC1.Nc1cccc(-c2ncc[nH]2)c1>>CC(C)(C)OC(=O)N1CC=C(c2cc3c(Nc4cccc(-c5ncc[nH]5)c4)ncnc3[nH]2)CC1,,CCCCO,,O=C(O)C(F)(F)F,,test
US20120232239A1,CC(C)OB1OC(C)(C)C(C)(C)O1.CCCCCCCCC1(CCCCCCCC)c2cc(Br)ccc2-c2ccc(Br)cc21>>CCCCCCCCC1(CCCCCCCC)c2cc(Br)ccc2-c2ccc(B3OC(C)(C)C(C)(C)O3)cc21,,CCOCC,,[Li]CCCC,,test
US20080227792A1,CC1(C)CC(=O)N(c2ccc(O)nc2)C(=O)C1.O=C(Cl)N1CCc2ccccc2C1>>CC1(C)CC(=O)N(c2ccc(OC(=O)N3CCc4ccccc4C3)nc2)C(=O)C1,,CN(C)C=O,,,,test
US20100022531A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCc2c(ncnc2NCC(O)C23CC4CC(CC(C4)C2)C3)C1>>N[C@@H](Cc1ccccc1)C(=O)N1CCc2c(ncnc2NCC(O)C23CC4CC(CC(C4)C2)C3)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06350749B1,Cc1ccnc2c1C(=NNC(=N)N)CC(c1sc(Cl)cc1Cl)C2.O=C1CC[C@@H](C(=O)O)N1>>Cc1ccnc2c1C(=NNC(=N)N)CC(c1sc(Cl)cc1Cl)C2.O=C1CC[C@@H](C(=O)O)N1,,CCO,,,,test
US20150336962A1,CC(C)N1CCNCC1.O=C(O)Cn1cc(NC(=O)c2cnn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1>>CC(C)N1CCN(C(=O)Cn2cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100197683A1,C=CC[Mg]Br.CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(C2CCC(=O)CC2)c2ncnn12>>C=CCC1(O)CCC(n2c(=O)c(Cc3ccc(-c4ccccc4C#N)cc3)c(CCC)n3ncnc23)CC1,,C1CCOC1,,[Cl-].[NH4+],,test
US20160130268A1,C=CC(=O)Cl.CCN(CC)CCCCNc1ncc2cc(-c3cc(OC)cc(OC)c3F)c(=O)n(CCc3cccc(N)c3)c2n1>>C=CC(=O)Nc1cccc(CCn2c(=O)c(-c3cc(OC)cc(OC)c3F)cc3cnc(NCCCCN(CC)CC)nc32)c1,,CO,ClCCl,,,test
US20070252511A1,Brc1ccc2ccc3c(Br)ccc4ccc1c2c43.OB(O)c1ccc2ccccc2c1.c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>c1ccc2cc(-c3ccc4ccc5c(-c6ccc7ccccc7c6)ccc6ccc3c4c65)ccc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US05102897,CCOC(=O)COc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.NN>>CC(C)(C)c1cc(OCC(=O)NN)cc(C(C)(C)C)c1O,,CCO,,O,O,test
US20140031360A1,CC(C)(C)OC(=O)n1cc(I)c2cc(C(=O)O)ccc21.CCN=C=NCCCN(C)C>>CC(C)(C)OC(=O)n1cc(I)c2cc(C(N)=O)ccc21,,CN(C)C=O,,Cl,,test
US04595521,CCCC[C@@H]1CC[C@@H](C=CC2OCCO2)CC1>>CCCC[C@@H]1CC[C@@H](CCC=O)CC1,[Pd],CCO,,CCN(CC)CC,,test
US20110086858A1,COC(=O)c1ccc(Nc2nc(NCCCOCCCCOCCCN)nc(OCC(F)(F)F)n2)cc1>>NCCCOCCCCOCCCNc1nc(Nc2ccc(C(=O)O)cc2)nc(OCC(F)(F)F)n1,,CC(C)=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20070281933A1,C1COCCN1.NC(=O)c1cc(-c2ccccc2)cc2c(C3CCN(S(=O)(=O)CCCCl)CC3)n[nH]c12>>NC(=O)c1cc(-c2ccccc2)cc2c(C3CCN(S(=O)(=O)CCCN4CCOCC4)CC3)n[nH]c12,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US05399703,CN(C)C(=O)CO.O=C(O)COc1ccc(C(=O)Nc2ccccc2Sc2ccccc2-c2nnn[nH]2)cc1>>CN(C)C(=O)COC(=O)COc1ccc(C(=O)Nc2ccccc2Sc2ccccc2-c2nnn[nH]2)cc1,,CN(C)C=O,O,CC(=O)O,,test
US20070197512A1,CCOC(=O)/C=C/C(=O)N1CCOc2c(C)cc(C)cc21>>Cc1cc(C)c2c(c1)N(C(=O)/C=C/C(=O)O)CCO2,,CC(C)(C)O,,[Na+].[OH-],,test
US05051520,O=C(O)c1ccc2c(c1)C(c1ccccc1)(C(F)(F)F)c1cc(C(=O)O)ccc1O2>>FC(F)(F)C1(c2ccccc2)c2ccccc2Oc2ccccc21,[Cu],c1ccc2ncccc2c1,,O=C=O,,test
US20110305729A1,CCOC(=O)CCCCCCN(c1ccccn1)c1ccc(OS(=O)(=O)C(F)(F)F)cn1.OB(O)c1ccccc1>>CCOC(=O)CCCCCCN(c1ccccn1)c1ccc(-c2ccccc2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20110144092A1,COc1cc(F)ccc1C=O.O=c1cc(-c2ccncn2)nc2n1CCCCC2>>COc1cc(F)ccc1C(O)C1CCCCn2c1nc(-c1ccncn1)cc2=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US06518306B1,COc1ccc(C2(c3ccc(-c4cnc(N)nc4)cc3)C=CC(=O)CC2)cc1OC1CCCC1>>COc1ccc(C2(c3ccc(-c4cnc(N)nc4)cc3)CCC(=O)CC2)cc1OC1CCCC1,[Pd],CCOC(C)=O,,,,test
US20110053955A1,CC(C)(C)OC(=O)NCCCc1c(C(=O)O)[nH]c2ccc(NC(=O)c3ccccc3)cc12.Cl>>Cl.NCCCc1c(C(=O)O)[nH]c2ccc(NC(=O)c3ccccc3)cc12,,C1COCCO1,ClCCl,,,test
US20120065191A1,CN(C(=O)Cl)c1ccccc1.c1ccc2[nH]cnc2c1>>CN(C(=O)n1cnc2ccccc21)c1ccccc1,,C1CCOC1,,c1ccncc1,,test
US20110213156A1,CC(C)c1cc(C(=O)O)[nH]c1C(C)C.COC(=O)c1ccc(N)cc1>>CC(C)c1cc(C(=O)Nc2ccc(C(=O)O)cc2)[nH]c1C(C)C,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20060167012A1,CCOC(C)=O.O=S(=O)(c1ccc2[nH]ccc2c1)N1CCN(c2ccc(C(F)(F)F)cc2)CC1>>COC(=O)Cn1ccc2cc(S(=O)(=O)N3CCN(c4ccc(C(F)(F)F)cc4)CC3)ccc21,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140045872A1,COc1ccc2c(c1)CCNC2=O.Cc1ccncc1I>>COc1ccc2c(c1)CCN(c1cnccc1C)C2=O,I[Cu]I,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20060111408A1,COc1ccc(-c2nc3c(Cl)cc(OC)cc3o2)c(Cl)c1>>Oc1ccc(-c2nc3c(Cl)cc(O)cc3o2)c(Cl)c1,,ClCCl,,BrB(Br)Br,CO,test
US20150005329A1,O=S(Cl)Cl.O=[N+]([O-])c1cc(Br)cc(CO)c1>>O=[N+]([O-])c1cc(Br)cc(CCl)c1,,CN1CCCC1=O,ClCCl,O=C([O-])O.[Na+],,test
US04496560,CN(C)c1ncc(C2=C(C(=O)OC(c3ccccc3)c3ccccc3)N3C(=O)C(NC(=O)Cc4cccs4)C3SC2)s1>>CN(C)c1ncc(C2=C(C(=O)O)N3C(=O)C(NC(=O)Cc4cccs4)C3SC2)s1,,O=CO,,,,test
US05977025,C=NC(C)(C)C(=O)OCc1ccccc1.CC1=C(c2ccccc2)C(=O)OC(C)(C)O1>>CC1=C(c2ccccc2)C(=O)N(C(C)(C)C(=O)OCc2ccccc2)CO1,,Cc1ccccc1C,,,,test
US04061761,CN=C1SCC(O)(c2ccc(Cl)c(S(N)(=O)=O)c2)N1C.Cc1ccc(S(=O)(=O)O)cc1>>CN=C1SCC(O)(c2ccc(Cl)c(S(N)(=O)=O)c2)N1C.Cc1ccc(S(=O)(=O)O)cc1,,CCO,,CC(C)OC(C)C,,test
US05442070,CCOC(=O)c1cc2cc(F)c(F)cc2nc1Cl.CNCCC(N)=O>>CCOC(=O)c1cc2cc(F)c(F)cc2nc1N(C)CCC(N)=O,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20050272744A1,Clc1ccc(-c2ccccc2CN2CCNCC2)cc1.N#Cc1ccc(F)cc1>>N#Cc1ccc(N2CCN(Cc3ccccc3-c3ccc(Cl)cc3)CC2)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04076938,CCOC(=O)NN(C#N)CC.CCS>>CCSc1nc(O)nn1CC,,CC(=O)O,,,,test
US20110294758A1,COC(=O)c1cc(O)cc(OC(C)C)c1.O=[N+]([O-])c1ccc(F)cc1>>COC(=O)c1cc(Oc2ccc([N+](=O)[O-])cc2)cc(OC(C)C)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090036492A1,COC(=O)CON.COc1cc(O)c2c(c1C(=O)NCc1c(C)ccc3ccccc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>COC(=O)CO/N=C(\C)C1=C(O)C=C2Oc3c(C(=O)NCc4c(C)ccc5ccccc45)c(OC)cc(O)c3[C@]2(C)C1=O,,C1CCOC1,CO,Cl,O=C([O-])O.[Na+],test
US20110212937A1,Clc1nc(Cl)c2c(n1)C(c1ccccc1)CC2.NC1CCC1>>Clc1nc(NC2CCC2)c2c(n1)C(c1ccccc1)CC2,,CN1CCCC1=O,,O,,test
US20120108574A1,O=C(CBr)c1ccccc1.O=C1Nc2cccnc2Nc2ccccc21>>O=C(CN1C(=O)c2ccccc2Nc2ncccc21)c1ccccc1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20060014953A1,Cc1cnc(C)c(NN)n1>>Cc1cnc(C)c(N)n1,[Ni],O,,,,test
US20130231328A1,CO[C@H](C[C@H]1CCc2sc3ncnc(OC4CCC(N(C)C(=O)OC(C)(C)C)CC4)c3c21)C(N)=O.Cl>>CNC1CCC(Oc2ncnc3sc4c(c23)[C@@H](C[C@@H](OC)C(N)=O)CC4)CC1.Cl,,ClCCl,,,,test
US05157041,CC(C)(C)N1CCC[C@@]1(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc(C(=O)OCc2ccccc2)cc1)C(N)=O.N#N>>CC(C)(C)N1CCC[C@@]1(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc(C(=O)O)cc1)C(N)=O.N#N,[Pd],CC(C)O,,,,test
US20070072853A1,CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(NCCO[Si](C)(C)C(C)(C)C)c([N+](=O)[O-])c2)cc1>>CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(NCCO[Si](C)(C)C(C)(C)C)c(N)c2)cc1,[Pd],CCOC(C)=O,,,,test
US06391874B1,CCCC[Sn](CCCC)(CCCC)c1conc1C.Ic1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1>>Cc1nocc1-c1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1,O=[Ag],C1COCCO1,,CCN(CC)CC,Cl,test
US05216148,CC(C)=CC(=O)Nc1cccc(Br)c1.CCCI>>CCCN(C(=O)C=C(C)C)c1cccc(Br)c1,,CS(C)=O,,[K+].[OH-],,test
US20030176418A1,CCCOC1CCNCC1.C[C@H](CI)CN1C(=O)CSc2ccccc21>>CCCOC1CCN(C[C@@H](C)CN2C(=O)CSc3ccccc32)CC1,,CC#N,,,,test
US20070043029A1,CC(=O)Cl.CC1(C)CCC(C)(C)c2cc3c(cc21)Nc1ccccc1N=C3c1ccc(C(=O)O)cc1>>CC(=O)N1c2ccccc2N=C(c2ccc(C(=O)O)cc2)c2cc3c(cc21)C(C)(C)CCC3(C)C,,ClCCl,,Cl,c1ccncc1,test
US20060116364A1,COc1ccc(C2CCc3cc(OC(=O)C(C)(C)C)ccc3C2)c(N(C(=O)c2ccc(OC(C)=O)c(F)c2)C(C)C)c1>>COc1ccc(C2CCc3cc(OC(=O)C(C)(C)C)ccc3C2)c(N(C(=O)c2ccc(O)c(F)c2)C(C)C)c1,,CO,,O,O=C([O-])[O-].[K+].[K+],test
US05332757,COC1(c2cc(F)cc(Sc3ccc(C(=O)c4ccccc4)cc3)c2)CCOCC1.NO>>COC1(c2cc(F)cc(Sc3ccc(C(=NO)c4ccccc4)cc3)c2)CCOCC1,,c1ccncc1,,Cl,,test
US06281231B1,CI.OCc1cc(Cl)nc(Cl)c1>>COCc1cc(Cl)nc(Cl)c1,,C1CCOC1,,CCOC(C)=O,[H-].[Na+],test
US20150320046A1,CC(C)(C)Sc1ccc(C2=CSC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1Br>>FC(F)(F)C1(c2cc(Cl)cc(Cl)c2)CC(c2ccc(S)c(Br)c2)=CS1,,ClCCl,,BrB(Br)Br,,test
US03946027,CCOC(=O)/C=C(/C)N.CCOC(=O)CC(=O)C(=O)OCC.CSc1ccc(C=O)cc1>>CCOC(=O)CC(=O)C(=O)OCC.COC(=O)/C=C(/C)N.CSc1ccc(C=O)cc1,,CCO,,,,test
US20060194960A1,CCOC(=O)C=Cc1ccc(C)cc1.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>CCOC(=O)c1c[nH]cc1-c1ccc(C)cc1,,CCOCC,O,CS(C)=O,[H-].[Na+],test
US20130345258A1,COc1cc2nccc(Cl)c2cc1Br.Cc1[nH]nc(N)c1C>>COc1cc2nccc(Nc3n[nH]c(C)c3C)c2cc1Br,,CCO,,CCOCC,,test
US20140288045A1,C=CS(=O)(=O)N1CC2CN(C(=O)OC(C)(C)C)CC2C1>>C=CS(=O)(=O)N1CC2CNCC2C1,,CO,Cl,,,test
US20110009454A1,Cl.NO.O=Cc1ccc(Oc2ccccc2)cc1>>Cl.NCc1ccc(Oc2ccccc2)cc1,[Pd],CCO,O,Cl,[H][H],test
US20080139631A1,CC(C)(C)C(=O)Nc1ccc(Cl)c(C(F)(F)F)c1C#C[Si](C)(C)C.N#C[Cu]>>N#Cc1ccc2[nH]ccc2c1C(F)(F)F,,CN1CCCC1=O,,[NH4+].[OH-],,test
US06635655B1,COC(=O)CCCCCc1cccc(CO)c1.O=C1CCC(=O)N1Br>>COC(=O)CCCCCc1cccc(CBr)c1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150307491A1,CC(=O)Cl.CN(C)c1ccc(-c2cc3nccnc3c(OC[C@@H]3CN(CCN)CCO3)n2)cc1>>CC(=O)NCCN1CCO[C@H](COc2nc(-c3ccc(N(C)C)cc3)cc3nccnc23)C1,,ClCCl,,CCN(CC)CC,,test
US20040214819A1,NS(N)(=O)=O.Nc1ccccc1CNC1CCN(Cc2ccccc2)CC1>>O=S1(=O)Nc2ccccc2CN1C1CCN(Cc2ccccc2)CC1,,c1ccncc1,,,,test
US20090233910A1,CC(C)N1CCC(Oc2cccc(C(=O)O)c2)CC1.On1nnc2ccccc21>>CC(C)N1CCC(ON2NN(OC(=O)c3ccccc3)c3ccccc32)CC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20140045819A1,N#Cc1cccc2c1CCC(=O)N2.O=C1CCC(=O)N1Br>>N#Cc1c(Br)ccc2c1CCC(=O)N2,,CN(C)C=O,,,,test
US20090054431A1,CC(=O)n1ncc2cc(Oc3ccc(C4OCCO4)cc3)ccc21>>CC(=O)n1ncc2cc(Oc3ccc(C=O)cc3)ccc21,,CC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20030013700A1,COC(=O)C(O)C(C)C1CC1>>C[C@@H](C1CC1)[C@@H](O)C(=O)O,,CO,,Cl,[Na+].[OH-],test
US20020002268A1,CCN(CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1CCCCC1)C(=O)OC)C(=O)CCCC1CCN(C(=O)OC(C)(C)C)CC1>>CCN(CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1CCCCC1)C(=O)O)C(=O)CCCC1CCN(C(=O)OC(C)(C)C)CC1,,CO,O,Cl,[Na+].[OH-],test
US20160060257A1,COc1ccc(F)cc1-c1ccnc2c1cc(C1(O)CC3(CN(C(=O)OC(C)(C)C)C3)C1)n2S(=O)(=O)c1ccc(C)cc1>>COc1ccc(F)cc1-c1ccnc2c1cc(C1(O)CC3(CNC3)C1)n2S(=O)(=O)c1ccc(C)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05401739,ClC/C=C/CCl.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1C/C=C/CCl,,CN(C)C=O,,[K],,test
US20060005321A1,BrCCBr.O=[N+]([O-])c1ccc(NS(=O)(=O)c2ccccc2)cc1>>O=[N+]([O-])c1ccc(N(CCBr)S(=O)(=O)c2ccccc2)cc1,,CN(C)C=O,,[K],,test
US20040063735A1,COC(=O)C(N)Cc1cc(C)c2[nH]ncc2c1.O=C(c1ncc[nH]1)c1ncc[nH]1.O=C1Nc2ccccc2CN1C1CCNCC1>>COC(=O)C(Cc1cc(C)c2[nH]ncc2c1)NC(=O)N1CCC(N2Cc3ccccc3NC2=O)CC1,,ClCCl,,,,test
US07241764B2,CCN(CC)C(=O)c1ccc([C@@H](c2cccc(NC3CCCCC3)c2)N2CCN(CC3CC3)CC2)cc1.CCN(CC)C(=O)c1ccc([C@@H](c2cccc(NC3CCCCC3)c2)N2CCNCC2)cc1>>CCN1CCN([C@@H](c2ccc(C(=O)N(CC)CC)cc2)c2cccc(NC3CCCCC3)c2)CC1,,CO,,,,test
US20120264737A1,COC(=O)c1ccc(C)c(-c2nc3c([nH]2)COCC3)c1>>Cc1ccc(C(=O)O)cc1-c1nc2c([nH]1)COCC2,,CO,O,[Na+].[OH-],,test
US20100280030A1,CC(=O)c1cccc([N+](=O)[O-])c1>>CC(O)c1cccc([N+](=O)[O-])c1,,CO,ClCCl,[BH4-].[Na+],,test
US20140066425A1,CC(C)(C)OC(=O)n1ccnc1CCCc1ccc([N+](=O)[O-])cn1>>CC(C)(C)OC(=O)n1ccnc1CCCc1ccc(N)cn1,[Pd],CCOC(C)=O,,,,test
US04094886,COC(=O)C12CC1CCC2=O.Sc1ccccc1>>COC(=O)C1=C(CSc2ccccc2)CCC1=O,,CC(C)(C)O,,CC(C)(C)[O-].[K+],,test
US20140094473A1,CC(=O)Cl.CC(C)(C)[C@H](N)CC(=O)O.CO>>COC(=O)C[C@@H]([NH3+])C(C)(C)C.[Cl-],,CO,,,,test
US04510143,NN.O=C(O)c1cnc2c(=O)[nH]c3ccccc3n2c1=O>>NNC(=O)c1cnc2c(=O)[nH]c3ccccc3n2c1=O,,CN(C)C=O,,O,O=C(n1ccnc1)n1ccnc1,test
US04853384,Fc1c(F)c(F)c(F)c(F)c1F.OC1(c2ccccc2)CCNCC1>>Fc1c(F)c(F)c(OC2(c3ccccc3)CCNCC2)c(F)c1F,,CN(C)C=O,,O,[H-].[Na+],test
US04321272,Clc1ccc(CCC2(Cn3ccnc3)OCCO2)cc1>>Clc1ccc(CCC2(Cn3ccnc3)OCCO2)cc1,,ClCCl,,Cl,O=C([O-])[O-].[K+].[K+],test
US20140315929A1,CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3ccc(C(N)=O)c(N[C@@H]4CC[C@@H](OC5CCCCO5)CC4)c3)c2C1>>CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3ccc(C(N)=O)c(N[C@@H]4CC[C@@H](O)CC4)c3)c2C1,,CCO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US05420309,O=[N+]([O-])O.O=[N+]([O-])c1ccc2c(c1)OC(CC(F)(F)F)(C(F)(F)F)O2>>O=[N+]([O-])c1cc2c(cc1[N+](=O)[O-])OC(CC(F)(F)F)(C(F)(F)F)O2,,O=S(=O)(O)O,,,,test
US20090062214A1,C/C=C/O[C@H]1O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](OCCCCCCCCCC)[C@H]1OCC[C@H](O)CCCCCCCCCCC.C=CCO.CCOC(C)=O.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.c1ccncc1>>C=CCOC(=O)O[C@H](CCCCCCCCCCC)CCO[C@H]1[C@@H](O/C=C/C)O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](OC(=O)OCC=C)[C@@H]1OCCCCCCCCCC,,Cc1ccccc1,,,,test
US20140121187A1,COC1(c2ccc(C(C)C)cc2O[Si](C)(C)C(C)(C)C)C(=O)c2ccccc2C1=O>>COC1(c2ccc(C(C)C)cc2O)C(=O)c2ccccc2C1=O,,C1CCOC1,,,,test
US20070117887A1,Cc1ccc(N2C(=O)c3cccc4c(Br)ccc(c34)C2=O)cc1.OCCO>>Cc1ccc(N2C(=O)c3cccc4c(OCCO)ccc(c34)C2=O)cc1,,O,,[Na+].[OH-],,test
US20160016908A1,CC(=O)N1c2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)cc2[C@H](Nc2ccc(C(=O)O)cc2)[C@@H](C)[C@@H]1C.[NH4+]>>CC(=O)N1c2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)cc2[C@H](Nc2ccc(C(N)=O)cc2)[C@@H](C)[C@@H]1C,,CN(C)C=O,CO,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05733882,CC(C)(C)[Si](C)(C)Cl.O[C@@H]1CCC[C@H]1O>>CC(C)(C)[Si](C)(C)O[C@@H]1CCC[C@H]1O,,CN(C)C=O,,c1c[nH]cn1,,test
US20150119362A1,CC(C)OC(=O)CC(=O)OC(C)C.O=[N+]([O-])c1ccc(CBr)cc1>>CC(C)OC(=O)C(Cc1ccc([N+](=O)[O-])cc1)C(=O)OC(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20070173530A1,CN(C)C=O.CN(C)c1ccncc1.COC(=O)CCc1ccc(N)cc1.O=C=Nc1cccc(C(F)(F)F)c1>>O=C(CCc1ccc(NC(=O)Nc2cccc(C(F)(F)F)c2)cc1)Nc1ccc2cnccc2c1,CN(C)c1ccncc1,,,O=C([O-])O.[Na+],,test
US20100173901A1,CC1Cc2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1.Cl>>CC1Cc2ccc(C3CCNCC3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1.Cl,,CCOC(C)=O,CCOCC,C1COCCO1,,test
US06881733B1,COC(=O)c1cc(Br)c2occc2c1>>OCc1cc(Br)c2occc2c1,,Cc1ccccc1,,CC(C)C[Al+]CC(C)C.[H-],,test
US04826866,CCCCCNC(=S)NN.CCOC(=O)C(Cl)C(C)=O>>CCCCCNc1n[nH]c(C)c1C(=O)OCC,,C1CCOC1,,,,test
US20030124155A1,CCCCCCCCCCCCCC(=O)Cl.N=C(N)NCCC[C@H](N)C(=O)O>>CCCCCCCCCCCCCC(=O)N[C@@H](CCCNC(=N)N)C(=O)O,,CC(C)O,O,Cl,[Na+].[OH-],test
US20050032873A1,CCCN(CCC(O)c1csc2ccc(F)cc12)C1COc2cccc(OC)c2C1>>CCCN(CCCc1csc2ccc(F)cc12)C1COc2cccc(OC)c2C1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US05278316,BrBr.Cc1ccc(S(=O)(=O)n2c(CO)cc3ccccc32)cc1>>Cc1ccc(S(=O)(=O)n2c(CBr)cc3ccccc32)cc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US05075316,O=P(Cl)(Cl)Cl.Oc1cc(C2CC2)nc(Nc2ccccc2)n1>>Clc1cc(C2CC2)nc(Nc2ccccc2)n1,,O,,Cl,[Na+].[OH-],test
US20060058325A1,CCOC(OCC)c1ncc(N)cn1.COc1cc2c(Cl)ncnc2cc1OCCCCl>>CCOC(OCC)c1ncc(Nc2ncnc3cc(OCCCCl)c(OC)cc23)cn1,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20060205790A1,BrP(Br)Br.NC(=O)Nc1cccc(CO)c1>>NC(=O)Nc1cccc(CBr)c1,,ClCCl,,,,test
US20130072519A1,C=O.CN1C(=O)c2ccccc2C1C(=O)OCc1ccccc1>>CN1C(=O)c2ccccc2C1(CO)C(=O)OCc1ccccc1,,C1COCCO1,,C1CCC2=NCCCN2CC1,,test
US20020077318A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)CN1c2ccc(Cl)c(Cl)c2[C@@H]2CCNCC[C@@H]21>>CCOC(=O)CN1c2ccc(Cl)c(Cl)c2[C@@H]2CCN(C(=O)OC(C)(C)C)CC[C@@H]21,,C1CCOC1,O,[Na+].[OH-],,test
US03988363,Cc1cc(C(C)(C)C)c(O)c(C)c1CC(=O)O.O=S(Cl)Cl>>Cc1cc(C(C)(C)C)c(O)c(C)c1CC(=O)Cl,,c1ccccc1,,CN(C)C=O,,test
US20140142144A1,CN(C)/C=C\C(=O)c1ccccn1.NN>>c1ccc(-c2cc[nH]n2)nc1,,CCO,,O,,test
US04472383,CC(C)(C)OC(=O)[C@@H](N)Cc1ccccc1.C[C@H](NC(=O)OCc1ccccc1)C(=O)N(CC(=O)O)C1CCCC1>>C[C@H](NC(=O)OCc1ccccc1)C(=O)N(CC(=O)N[C@@H](Cc1ccccc1)C(=O)OC(C)(C)C)C1CCCC1,,CN(C)C=O,,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US06562823B1,N#Cc1ccc(Cn2cncc2CN2CCN(c3cc(Cl)ccc3-c3ccccc3OCc3ccccc3)C(=O)C2)cc1F.O=C(O)C(F)(F)F>>N#Cc1ccc(Cn2cncc2CN2CCN(c3cc(Cl)ccc3-c3ccccc3O)C(=O)C2)cc1F.O=C(O)C(F)(F)F,[Pd],CCOC(C)=O,CO,[H][H],,test
US05405865,C#C[Mg]Br.O=Cc1cc(C(F)(F)F)co1>>C#CC(O)c1cc(C(F)(F)F)co1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20140356322A1,COCCC(=O)O.Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)CN)cc1>>COCCC(=O)NCC(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05021420,COc1ccc(C2=CCNCC2)cc1.O=S1(=O)c2cccc3cccc(c23)N1CCCCl>>COc1ccc(C2=CCN(CCCN3c4cccc5cccc(c45)S3(=O)=O)CC2)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20040087589A1,Cc1cc(C)c(-n2c(C)cc3c2=NC(C)NC=3Cl)c(C)c1.O=C(Cl)CCl>>Cc1cc(C)c(-n2c(C)c(C(=O)CCl)c3c2=NC(C)NC=3Cl)c(C)c1,,ClC(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20110263549A1,Cc1cc(-c2cc3ncccc3c(Cl)n2)ccc1N(C)C.OC1(O)CCCCC1>>Cc1cc(-c2cc3ncccc3c([C@@H]3CC[C@@H](O)CC3)n2)ccc1N(C)C,,CC(=O)N(C)C,ClCCl,[H-].[Na+],,test
US20080181866A1,COC(=O)c1cccc([C@H]2SCC(C(=O)O)N2C(=O)OCc2ccccc2)c1.Nc1nc(-c2ccc(C(=O)NC3CC3)cc2)cs1>>COC(=O)c1cccc([C@H]2SCC(C(=O)Nc3nc(-c4ccc(C(=O)NC5CC5)cc4)cs3)N2C(=O)OCc2ccccc2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05786367,C=CCc1cc2c(c(CC=C)c1O)CCC(=O)N2CCCN.O=C(Cl)CCl>>C=CCc1cc2c(c(CC=C)c1O)CCC(=O)N2CCCNC(=O)CCl,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20140275568A1,CCOC(OCC)OCC.Cl.NC(=O)C(N)C(N)=O.O.O>>Cl.NC(=O)c1nc[nH]c1O.O.O,,CC(C)O,O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20110301143A1,CCOC(=O)Cn1nnc(-c2cnc(N3CCNCC3)s2)n1.O=C(Cl)c1cccc(F)c1C(F)(F)F>>CCOC(=O)Cn1nnc(-c2cnc(N3CCN(C(=O)c4cccc(F)c4C(F)(F)F)CC3)s2)n1,,ClCCl,,CCN(CC)CC,Cl,test
US20140194431A1,CN(CCO[Si](C)(C)C(C)(C)C)C(=O)c1nc(CC2(n3ccc4cccnc43)CCCC2)nc(O)c1OCc1ccccc1>>CN(CCO)C(=O)c1nc(CC2(n3ccc4cccnc43)CCCC2)nc(O)c1OCc1ccccc1,,C1CCOC1,,Cl,,test
US20100286115A1,CCOC(=O)N=NC(=O)OCC.COC(=O)c1cc(O)n[nH]1.Cc1onc(-c2ccccc2)c1CO>>COC(=O)c1cc(OCc2c(-c3ccccc3)noc2C)nn1C,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20160159752A1,CC(C)[C@H](c1ccc(Cl)cc1)[C@H](N=[N+]=[N-])C(=O)Nc1cncc(F)c1CCC1C[N@@]1S(=O)(=O)c1ccccc1.C[C@@H](O)CN>>CC(C)[C@H](c1ccc(Cl)cc1)[C@H](N=[N+]=[N-])C(=O)Nc1cncc(F)c1CC[C@@H](CNC[C@@H](C)O)NS(=O)(=O)c1ccccc1,,ClCCCl,O,,,test
US20100069357A1,CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOC[C@@H]4C)n2)CCNC3)cc1.CN(C)C(=O)CCl>>CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOC[C@@H]4C)n2)CCN(CC(=O)N(C)C)C3)cc1,,CN(C)C=O,,[I-].[K+],,test
US04906666,CCCCCC(O)c1cccc(O)c1.ClCC1CO1>>CCCCCC(O)c1cccc(OCC2CO2)c1,,CCO,O,[K+].[OH-],,test
US20090048239A1,CN[C@H]1COc2ccccc2-c2c(C3CCCCC3)c3ccc(C(=O)OC)cc3n2C1.O=CCCl>>COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)C[C@@H](N(C)CCCl)COc1ccccc1-3,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20020042443A1,Brc1ccc(OCCN2CCCC2)cc1.COc1cc2c(cc1OC)C(=O)CCC2>>COc1cc2c(cc1OC)C(c1ccc(OCCN3CCCC3)cc1)=CCC2,,C1CCOC1,CCOCC,[Li]CCCC,,test
US20020013318A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.CS(=O)(=O)c1ccc(-c2cnn(Cc3ccccc3)c(=O)c2-c2ccc(F)cc2)cc1>>CS(=O)(=O)c1ccc(-c2cnn(Cc3ccccc3)c(=S)c2-c2ccc(F)cc2)cc1,,Cc1ccccc1,,,,test
US04921855,CC(C)CCC(O)CN(C)C(=O)OC(C)(C)C>>CC(C)CCC(=O)CN(C)C(=O)OC(C)(C)C,,CS(C)=O,,CCN(CC)CC,,test
US05185358,CCCCCCCCCCCC(=O)NNC(N)=S>>CCCCCCCCCCCc1nnc(N)s1,,Cc1ccccc1,,CS(=O)(=O)O,,test
US20070129346A1,CC(C)(C)OC(=O)NCC(=O)O.O=C(OCc1ccccc1)N1CC[C@H](NC2CCCCC2)C1>>CC(C)(C)OC(=O)NCC(=O)N(C1CCCCC1)[C@H]1CCN(C(=O)OCc2ccccc2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080096859A1,CC(C)(C)OC(=O)N1CC[C@@H](COS(C)(=O)=O)C1.N[C@@H](CO)c1ccccc1>>OCC(NCN1CCCC1)c1ccccc1,,Cc1ccccc1,,,,test
US20040023974A1,COc1ccc(CN2C(=O)CN(Cc3ccc4c(OC)ccnc4c3)S2(=O)=O)c(OC)c1>>COc1ccnc2cc(CN3CC(=O)NS3(=O)=O)ccc12,,ClCCl,O=C(O)C(F)(F)F,,,test
US20120270863A1,COc1ccc(/C=C/C(=O)O)cc1OC.Nc1ccccc1S(N)(=O)=O>>COc1ccc(/C=C/C2=NS(=O)(=O)c3ccccc3N2)cc1OC,,CC#N,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05466823,CC(=O)C1=CCCCC1.CCOC(=O)C(F)F>>O=C(CC(=O)C1C=CCCC1)C(F)F,,CCOCC,,Cl,C[O-].[Na+],test
US20090036685A1,CCOC(=O)c1cn2cncc2s1.O=C(Cl)c1cccnc1>>CCOC(=O)c1cn2cnc(C(=O)c3cccnc3)c2s1,Cl[Ti](Cl)(Cl)Cl,ClCCCl,,O=C([O-])O.[Na+],,test
US05399553,CCOC(=O)C1CN2c3c(c(F)c(F)c(F)c3C1=O)CCN2C>>CN1CCc2c(F)c(F)c(F)c3c(=O)c(C(=O)O)cn1c23,,O,,CC(=O)O,Cl,test
US20160052884A1,N=C(N)C(F)(F)F.O=C(CBr)c1ccc([N+](=O)[O-])cc1>>O=[N+]([O-])c1ccc(-c2cnc(C(F)(F)F)[nH]2)cc1,,CC#N,,O=S(=O)([O-])[O-].[Na+].[Na+],,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Nc1ccc(-c2nnn[nH]2)cc1>>COc1ccc2nc(Nc3ccc(-c4nnn[nH]4)cc3)c3[nH]ncc3c2c1,C1COCCO1,CO,,Cl,,test
US04518415,C=C(CCC(=O)OC)c1ccc(Cl)cc1>>C=C(CCCO)c1ccc(Cl)cc1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110230458A1,CCCCc1nnc(OC2CCN(C)CC2)cc1-c1ccc(OCc2ccccc2)c(OC)c1>>CCCCc1nnc(OC2CCN(C)CC2)cc1-c1ccc(O)c(OC)c1,[Pd],CCOC(C)=O,CO,,,test
US20060069096A1,C[C@@H](O)Cn1ncc2ccc(O)c([N+](=O)[O-])c21>>C[C@@H](O)Cn1ncc2ccc(O)c(N)c21,[Pd],CO,,,,test
US05776929,Cc1cccc(N=C=O)c1.NC1C(=O)Nc2ccccc2NC1=O>>Cc1cccc(NC(=O)NC2C(=O)Nc3ccccc3NC2=O)c1,,CN(C)C=O,,CC(C)OC(C)C,,test
US05559230,CC(=O)OC(C)=O.O=C(Nc1ccc(C(=O)N2CCCC(=NO)c3ccccc32)cc1)c1ccccc1Cl>>CC(=O)ON=C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3Cl)cc2)c2ccccc21,,c1ccncc1,,,,test
US20090247746A1,CCOC(=O)c1cc2ccc(C)c(N)c2[nH]1.O=S(=O)(Cl)c1cccs1>>CCOC(=O)c1cc2ccc(C)c(NS(=O)(=O)c3cccs3)c2[nH]1,,c1ccncc1,,,,test
US20100209378A1,CC(O)C(=O)O.CC(O)C1CCCC(C)(C)C1>>CC(O)C(=O)OC(C)C1CCCC(C)(C)C1,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,,,test
US20160158207A1,CC(O)C1CC1.CS(=O)(=O)Cl>>CC(OS(C)(=O)=O)C1CC1,,ClCCl,,,,test
US20030232812A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C(NC[C@H]1CN(c2ccc(C3C=CS(=O)(=O)CC3)c(F)c2)C(=O)O1)C(F)F>>O=C1O[C@@H](CNC(=S)C(F)F)CN1c1ccc(C2C=CS(=O)(=O)CC2)c(F)c1,,C1COCCO1,,,,test
US20050043388A1,CC(C)(C)OC(=O)NNC(=O)c1ccc(N)cc1.COC(=O)c1ccc(C(=O)Cl)cc1>>COC(=O)c1ccc(C(=O)Nc2ccc(C(=O)NNC(=O)OC(C)(C)C)cc2)cc1,,c1ccncc1,,,,test
US20080132503A1,COC(=O)CCCCCCC(=O)Nc1cccc(-c2ccccc2)c1>>O=C(O)CCCCCCC(=O)Nc1cccc(-c2ccccc2)c1,,C1CCOC1,,[K+].[OH-],,test
US03991064,COc1cc2[nH]c(=O)c3c(c2cc1OC)CCNC3.ClCCN1CCCCC1>>COc1cc2[nH]c(=O)c3c(c2cc1OC)CCN(CCN1CCCCC1)C3,,CCO,,CCN(CC)CC,Cl,test
US20100240702A1,CCCC(CC(=O)OCC)n1c(=O)[nH]c2ccc(C)cc21.Cc1cccc2c1c(C[N+](C)(C)C)cn2C>>CCCC(CC(=O)OCC)n1c(=O)n(Cc2cn(C)c3cccc(C)c23)c2ccc(C)cc21,,CCOC(C)=O,CN(C)C=O,[I-].[K+],,test
US20110071150A1,CCn1nc(-c2cnccn2)nc1-c1ccc([N+](=O)[O-])c(CC(=O)c2c(F)cccc2Cl)c1>>CCn1nc(-c2cnccn2)nc1-c1ccc2[nH]c(-c3c(F)cccc3Cl)cc2c1,[Fe],CC(=O)O,,,,test
US20060287522A1,CC(O)c1ccccc1-c1ccc(C(=O)N2Cc3ccc(C(=O)NCc4cccnc4)n3Cc3ccccc32)cc1.O=C(OO)c1cccc(Cl)c1>>CC(O)c1ccccc1-c1ccc(C(=O)N2Cc3ccc(C(=O)NCc4ccc[n+]([O-])c4)n3Cc3ccccc32)cc1,,ClCCl,,O=C([O-])O.[Na+],,test
US20070010402A1,Cc1cc2c(S(C)(=O)=O)nc(OCC(F)(F)F)nc2s1.Oc1cccc(C(F)(F)F)c1>>Cc1cc2c(Oc3cccc(C(F)(F)F)c3)nc(OCC(F)(F)F)nc2s1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20120029190A1,COc1ccc(-c2nc3c(o2)CCN(c2cnccn2)C3)cc1.N#Cc1cccnc1Cl>>COc1ccc(-c2nc3c(o2)CCN(c2ncccc2C#N)C3)cc1,,CCOC(C)=O,,,,test
US20090252679A1,CCOc1ccc(C(=O)CBr)cc1.Nc1ccc(I)cn1>>CCOc1ccc(-c2cn3cc(I)ccc3n2)cc1,,CC#N,,,,test
US20120028961A1,C=CCc1ccc2c(c1O)CCN(C(=O)C(F)(F)F)CC2>>CCCc1ccc2c(c1O)CCN(C(=O)C(F)(F)F)CC2,[Pd],CCOC(C)=O,,,,test
US20080161328A1,Cc1ccccc1C(=O)O.Cc1nc2cccc(CN)c2c(=O)n1C1CCC(=O)NC1=O>>Cc1cccc(C(=O)NCc2cccc3nc(C)n(C4CCC(=O)NC4=O)c(=O)c23)c1,,CN(C)C=O,,Cl,O=C(n1ccnc1)n1ccnc1,test
US20120088750A1,CCOC(=O)C1(C)CCN(c2ncc(-c3cc(COCCOC)c4sc(N5CN(C)CN(CC)C5=O)nc4c3)cn2)CC1>>CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)O)CC4)nc3)cc(COCCOC)c2s1,,CCO,,Cl,[Na+].[OH-],test
US08895313B2,CCOP(=O)(Cc1ccc(-c2nc3ccc(OC)cc3s2)cc1)OCC.O=Cc1ccc(Cl)c([N+](=O)[O-])c1>>COc1ccc2nc(-c3ccc(C=Cc4ccc(Cl)c([N+](=O)[O-])c4)cc3)sc2c1,,C1CCOC1,,[H-].[Na+],,test
US04980082,CCOC(=O)c1ccc(OCCCO[C@H]2CCCCO2)cc1>>CCOC(=O)c1ccc(OC[C@H](C)O)cc1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20080021053A1,CC(=O)CC(=O)C(C)C.N#Cc1ccc(C=O)cc1.NC(=O)Nc1cccc(C(F)(F)F)c1>>CC1=C(C(=O)C(C)C)C(c2ccc(C#N)cc2)NC(=O)N1c1cccc(C(F)(F)F)c1,,C1CCOC1,,,,test
US20110112158A1,Fc1cc(Cl)c(-c2ccc(OCc3cccc4c(OC(c5ccccc5)(c5ccccc5)c5ccccc5)noc34)cc2)cc1F>>Oc1noc2c(COc3ccc(-c4cc(F)c(F)cc4Cl)cc3)cccc12,,C1CCOC1,,,,test
US05981533,CCOC(OCC)N(C)C.CCOc1ccc(Nc2n[nH]c(N)c2C#N)cc1>>CCOc1ccc(Nc2n[nH]c(N=CN(C)C)c2C#N)cc1,,Cc1ccccc1,,,,test
US20140349990A1,CCOC(=O)c1c(C(O)c2ccc(Cl)cc2)cnn1C(C)C.Cn1cc(N)cc(Cl)c1=O>>CCOC(=O)c1c(C(Nc2cc(Cl)c(=O)n(C)c2)c2ccc(Cl)cc2)cnn1C(C)C,,CCOC(C)=O,,,,test
US20120184540A1,CCCCNc1ccc(F)c([C@]2(C)COCC(NC(c3ccccc3)(c3ccc(OC)cc3)c3ccc(OC)cc3)=N2)c1>>CCCCNc1ccc(F)c([C@]2(C)COCC(N)=N2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050032786A1,CC(C)(C)OC(=O)CCOCc1cccc(C#N)n1.COC(=O)c1ccccc1S>>CC(C)(C)OC(=O)CCOCc1cccc(-c2nc(=O)c3ccccc3s2)n1,,Cc1ccccc1,,CCN(CC)CC,,test
US20100099695A1,CC(C)[C@H](NC(=O)OCCCCC(=O)N1CCc2cccc(O)c2C1)C(=O)OC(C)(C)C.COC(=O)[C@@H]1C[C@H](OS(=O)(=O)c2ccc(Br)cc2)CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1C[C@@H](Oc2cccc3c2CN(C(=O)CCCCOC(=O)N[C@H](C(=O)OC(C)(C)C)C(C)C)CC3)CN1C(=O)OC(C)(C)C,,CCOC(C)=O,CN1CCCC1=O,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20150004135A1,CC(C)OC(=O)[C@H](C)N.Cl.O=P(Cl)(Cl)Oc1ccc2ccccc2c1>>CC(C)OC(=O)[C@H](C)N=[P+]([O-])Oc1ccc2ccccc2c1Cl,,ClCCl,,CCN(CC)CC,,test
US20120252780A1,Nc1cncc(Cl)n1.O=C1CCC(=O)N1Br>>Nc1nc(Cl)cnc1Br,,ClC(Cl)Cl,,,,test
US20150152108A1,Cc1ccc(-c2ccc3c(n2)N[C@H]2CCN3C2)cn1.NC1CCOCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>Cc1ccc(-c2ccc3c(n2)N(C(=O)NC2CCOCC2)[C@H]2CCN3C2)cn1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20130310379A1,COC(=O)c1ccc(Nc2ccccc2)nc1>>O=C(O)c1ccc(Nc2ccccc2)nc1,,C1CCOC1,CO,[Li+].[OH-],,test
US20160002188A1,Cl.Cn1cnc2cc(-c3ccc(C(=O)N4CCN(C(=O)OC(C)(C)C)CC4)cc3)ccc21>>Cl.Cn1cnc2cc(-c3ccc(C(=O)N4CCNCC4)cc3)ccc21,,ClCCl,,,,test
US20050107373A1,CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)N(Cc1ccccc1)CN2c1ccccc1>>O=C1N(Cc2ccccc2)CN(c2ccccc2)C12CCNCC2,,CCOC(C)=O,CCOCC,Cl,,test
US20070003789A1,CB1OB(C)OB(C)O1.Cc1c(Br)cnc(N)c1C>>Cc1cnc(N)c(C)c1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05849757,Cc1c(F)c(F)c([N+](=O)[O-])c(C(=O)O)c1F.O=S(Cl)Cl>>Cc1c(F)c(F)c([N+](=O)[O-])c(C(=O)Cl)c1F,,c1ccccc1,,,,test
US20020010182A1,O=C1CN(Cc2ccccc2)C(=O)[C@@H](Cc2ccc(F)cc2)N1>>Fc1ccc(C[C@@H]2CN(Cc3ccccc3)CCN2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US07019147B1,COCCOc1ccc2c(c1)ncn2-c1ccc2cccc(O)c2n1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>COCCOc1ccc2c(c1)ncn2-c1ccc2cccc(OS(=O)(=O)C(F)(F)F)c2n1,,C1CCOC1,CN(C)C=O,CCN(CC)CC,,test
US05250549,CI.COc1ccc(Nc2ncccc2NS(=O)(=O)c2ccc(OC)cc2)cc1>>COc1ccc(Nc2ncccc2N(C)S(=O)(=O)c2ccc(OC)cc2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US05969070,O=C1Cc2ccccc2C1>>C1=Cc2ccccc2C1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100105744A1,CSCc1cccc2c(C(CCC#N)c3ccc(C(F)(F)F)cc3)c[nH]c12.O=C(OO)c1cccc(Cl)c1>>CS(=O)Cc1cccc2c(C(CCC#N)c3ccc(C(F)(F)F)cc3)c[nH]c12,,ClCCl,,,,test
US20100324047A1,Brc1ncnc2[nH]cnc12.COc1ccc(CCl)cc1>>COc1ccc(Cn2cnc3c(Br)ncnc32)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130026452A1,Clc1ccnc(Cl)c1.OB(O)c1cccc2c1oc1ccccc12>>Clc1ccnc(-c2cccc3c2oc2ccccc23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20140243526A1,CC(C=O)CCC(=O)C1=CCCC(C)(C)C1>>CC(CO)CCC(=O)C1=CCCC(C)(C)C1,,Cc1ccccc1,,,,test
US20070249688A1,COc1ccc(Br)c(C=O)c1>>O=Cc1cc(O)ccc1Br,,ClCCl,,BrB(Br)Br,,test
US20020013302A1,CC(C)CCC[C@@H](C)C1=CC[C@H]2[C@@H]3CC=C4C(C)(C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C.O=C(Cl)c1ccccc1>>CC(C)CCC[C@@H](C)C1=CC[C@H]2[C@@H]3CC=C4C(C)(C)[C@@H](OC(=O)c5ccccc5)CC[C@]4(C)[C@H]3CC[C@]12C,,c1ccncc1,,,,test
US20110275611A1,CC(C)(C)C(=O)Cl.C[C@@H]1CO[C@H](CN)CN1c1cc(-c2ccc(C#N)c(F)c2)nc(N)n1>>C[C@@H]1CO[C@H](CNC(=O)C(C)(C)C)CN1c1cc(-c2ccc(C#N)c(F)c2)nc(N)n1,,C1CCOC1,,CCN(CC)CC,,test
US04772600,CCCNCCC.O=C(O)Cn1c(-c2ccc(Cl)cc2)nc2ncccc21>>CCCN(CCC)C(=O)Cn1c(-c2ccc(Cl)cc2)nc2ncccc21.O,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20160024009A1,CCI.COC(=O)C1(NS(=O)(=O)c2ccc(Cl)s2)CC1>>CCN(C1(C(=O)OC)CC1)S(=O)(=O)c1ccc(Cl)s1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140107097A1,COc1nc2c(C)cc(Br)cc2c(Cl)c1-c1cccc(F)c1.Cn1cncc1C(=O)c1ccc(C(F)(F)F)nc1>>COc1nc2c(C)cc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1-c1cccc(F)c1,,C1CCOC1,,[Li]CCCC,,test
US20030228469A1,OCCCCCCC(I)CC(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>OCCCCCCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F,[Zn],CCO,,CC(=O)O,,test
US06090825,CC(=O)N1CCC(c2nc(CCl)c(-c3ccccc3)o2)CC1.OCC(F)(F)F>>CC(=O)N1CCC(c2nc(COCC(F)(F)F)c(-c3ccccc3)o2)CC1,,O,,[Na+].[OH-],,test
US06448266B1,CC(C)(C)OC(=O)NC1(C2CNC(=O)C2)CC(OCc2ccccc2)C1.ClCc1ccccc1>>CC(C)(C)OC(=O)NC1(C2CC(=O)N(Cc3ccccc3)C2)CC(OCc2ccccc2)C1,,C1CCOC1,O,CN(C)C=O,[H-].[Na+],test
US06262241B1,NCCCn1ccnc1.OC[C@H]1O[C@@H](n2cnc3c(O)nc(Cl)nc32)C[C@@H]1O>>O=c1[nH]c(NCCCn2ccnc2)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1,,COCCO,,,,test
US20160194321A1,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.OCc1ccc(Br)cc1F>>Cn1cc(-c2ccc(CO)c(F)c2)cn1,,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20070078121A1,O=C(NCCc1cccc([N+](=O)[O-])c1)C(F)(F)F>>Nc1cccc(CCNC(=O)C(F)(F)F)c1,[Pd],CO,,,,test
US20160159752A1,C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H](CCc2c(F)cncc2NC(=O)[C@@H](N)[C@@H](c2ccc(F)cc2)c2cc(F)cc(F)c2)N1S(=O)(=O)c1ccccc1>>C[C@@H]1CNC[C@H](CCc2c(F)cncc2NC(=O)[C@@H](N)[C@@H](c2ccc(F)cc2)c2cc(F)cc(F)c2)N1S(=O)(=O)c1ccccc1,,CC1CCCO1,,Cl,,test
US20110257137A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(Cl)cc1I>>CC(C)(C)OC(=O)Nc1ccc(Cl)cc1I,CN(C)c1ccncc1,c1ccncc1,,,,test
US20150005275A1,CC(=O)Nc1sc(S(=O)(=O)c2ccccc2)c(C)c1C(N)=O>>Cc1c(S(=O)(=O)c2ccccc2)sc(N)c1C(=O)O,,Cl,,C1COCCO1,,test
US20040176370A1,CC(C)(C)[Si](C)(C)Cl.CC(O)CCCl>>CC(CCCl)O[Si](C)(C)C(C)(C)C,,CN(C)C=O,,c1c[nH]cn1,,test
US20090312369A1,O=C(O)C1(CCCCl)C[C@H]2CO[C@H](c3ccccc3)N2C1=O>>O=C1[C@H](CCCCl)C[C@H]2CO[C@H](c3ccccc3)N12,,Cc1ccccc1,,,,test
US05409928,CC(=O)Cl.Cc1cccc(C(O)c2ccc(CO[Si](C)(C)C(C)(C)C)cc2C)c1.O>>CC(=O)OC(O)(c1cccc(C)c1)c1ccc(CO[Si](C)(C)C(C)(C)C)cc1C,CN(C)c1ccccn1,c1ccncc1,,ClCCl,,test
US20110281854A1,C[C@@H]1CN[C@H](c2ccccc2)CO1.O=S1(=O)COc2ccc(Br)cc2N1>>C[C@@H]1CN(c2ccc3c(c2)NS(=O)(=O)CO3)[C@H](c2ccccc2)CO1,,CS(C)=O,,,,test
US20060258721A1,O=C(Cl)C(=O)Cl.O=C(O)C[C@@H]1CCCN1C(=O)OCc1ccccc1>>O=C(Cl)C[C@@H]1CCCN1C(=O)OCc1ccccc1,CN(C)C=O,ClCCl,,,,test
US20080188521A1,CC(N)=O.Cc1ccc2c(C(=O)CBr)cc(=O)oc2c1>>Cc1ccc2c(-c3coc(C)n3)cc(=O)oc2c1,,CN(C)C=O,,CCOC(C)=O,,test
US04798827,CC(=O)SC1CN2CCC1CC2>>SC1CN2CCC1CC2,,CO,,CC(=O)O,C[O-].[Na+],test
US05011825,CC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1)C(=O)OC(C)(C)C>>CC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1)C(=O)O,,O=C(O)C(F)(F)F,,,,test
US03984563,CC(=O)OC(C)=O.Cn1c(N)c(-c2ccc(Cl)cc2)c2ccccc21>>CC(=O)Nc1c(-c2ccc(Cl)cc2)c2ccccc2n1C,,c1ccncc1,,Cl,,test
US20090233937A1,CC(C)(C)C(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(F)c3)c21.CS(=O)(=O)O>>CC(C)(C)C(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(F)c3)c21.CS(=O)(=O)O,,CCO,CCOC(C)=O,,,test
US04613676,CC(C)(C)OC(=O)CCCCCCC[NH-].CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@H](C(=O)O)C(C)C>>CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@H](C(=O)O)C(C)C.[NH-]CCCCCCCC(=O)O,,O=C(O)C(F)(F)F,,,,test
US20120232056A1,COC(=O)c1ccc2nc(-c3ccc4[nH]cc(C)c4c3)c(N(C)C(C)C)nc2c1>>Cc1c[nH]c2ccc(-c3nc4ccc(C(=O)O)cc4nc3N(C)C(C)C)cc12,,CO,,O,[Na+].[OH-],test
US20050171163A1,CS(CC(O)CF)(c1ccc(Cl)cc1)c1ccc(Cl)cc1>>CS(CC(=O)CF)(c1ccc(Cl)cc1)c1ccc(Cl)cc1,,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20050197337A1,C#CCN1CCOCC1.CON(C)C(C)=O>>CC(=O)C#CCN1CCOCC1,,C1CCOC1,,CC(C)[Mg]Cl,[Cl-].[NH4+],test
US20050130930A1,C#CCCCCC#N.Nc1nc(I)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>N#CCCCCC#Cc1nc(N)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,CC(C)NC(C)C,,test
US04788206,COc1ccc(/C(=C/C=C/C(=O)O)C2CC2)cc1.O=[N+]([O-])c1ccc(O)cc1>>COc1ccc(/C(=C/C=C/C(=O)Oc2ccc([N+](=O)[O-])cc2)C2CC2)cc1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20080287475A1,CC(C)Oc1cc(Nc2nc(NC(C)c3ncc(F)cn3)ncc2Cl)n[nH]1.C[C@H](Nc1ncc(F)c(Nc2cc(C3CC3)[nH]n2)n1)c1ncc(F)cn1>>Cc1cc(Nc2nc(NC(C)c3ncc(F)cn3)ncc2Cl)n[nH]1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20040082607A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)Cn1c(CN)c(-c2ccccc2)c2cc(Br)ccc2c1=O>>CC(C)Cn1c(CNC(=O)OC(C)(C)C)c(-c2ccccc2)c2cc(Br)ccc2c1=O,CN(C)c1ccncc1,C1CCOC1,,O,,test
US20050004186A1,CCc1ccc(Nc2c(C(=O)NNC(C)=N)ccc(F)c2F)c(F)c1>>CCc1ccc(Nc2c(-c3nnc(C)[nH]3)ccc(F)c2F)c(F)c1,,Cc1ccccc1C,,,,test
US05342846,O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O.c1ncn(C2CCCNC2)n1>>O=C(O)c1cn(C2CC2)c2c(F)c(N3CCCC(n4cncn4)C3)c(F)cc2c1=O,,CC#N,,C1CCC2=NCCCN2CC1,Cl,test
US20120184531A1,CC(C)(C)OC(=O)N1CCc2oc3c(Cl)cc(C(C)(O)c4ccccc4)cc3c2C1>>C=C(c1ccccc1)c1cc(Cl)c2oc3c(c2c1)CNCC3,,ClCCl,,O=C(O)C(F)(F)F,,test
US06211234B1,CCOC(=O)C(=O)CC(=O)c1ccc(OCc2ccccc2)cc1OCc1ccccc1>>O=C(O)C(=O)CC(=O)c1ccc(OCc2ccccc2)cc1OCc1ccccc1,,CO,,[K+].[OH-],,test
US20150353479A1,C=CC#N.C=CCCCCCCCC(=O)OC>>C=CC#N.C=CCCCCCCCC(=O)OC,,Cc1ccccc1,,,,test
US20160176868A1,CC(C)N=C=O.CCOC(=O)C1=C(N)N[C@@H](c2cccc(OC)c2)CC1>>CCOC(=O)C1=C(NC(=O)NC(C)C)N[C@@H](c2cccc(OC)c2)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20040209921A1,CC1CSCC1CN1C(=O)c2ccccc2C1=O.O=C1CCC(=O)N1Br>>O=C1c2ccccc2C(=O)N1Cc1cscc1CBr,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US04797413,CC1(C)CC(=O)c2cc(S(N)(=O)=O)sc2S1.CCN>>CCNC1CC(C)(C)Sc2sc(S(N)(=O)=O)cc21,Cl[Ti](Cl)(Cl)Cl,C1CCOC1,c1ccccc1,[BH4-].[Na+],,test
US20040167131A1,NC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2F)CC1.O=C=Nc1ccc(Cl)cc1>>NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2(NC(=O)Nc3ccc(Cl)cc3)CC2)c(F)c1,,C1CCOC1,,CCN(CC)CC,,test
US20020156081A1,Fc1ccccc1C(=S)Nc1ccc(Br)cc1.NN>>NN=C(Nc1ccc(Br)cc1)c1ccccc1F,,C1CCOC1,CCO,,,test
US04801733,CCOP(=O)(Cc1ccc(C#N)cc1)OCC.COc1c(C=O)c(C)cc2c1C(C)(C)CCC2(C)C>>COc1c(/C=C/c2ccc(C#N)cc2)c(C)cc2c1C(C)(C)CCC2(C)C,,CS(C)=O,O,Cl,[H-].[Na+],test
US20100120785A1,CC(=O)c1ccc(B(O)O)cc1.Cc1c(CN2CCN(c3nccnc3Cl)CC2)cnn1C>>CC(=O)c1ccc(-c2nccnc2N2CCN(Cc3cnn(C)c3C)CC2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(=O)N(C)C,,O,O=C([O-])[O-].[K+].[K+],test
US05376681,CC(=O)Cl.Cc1c(C)c2c(c(C)c1N)CC(C)(C)O2>>CC(=O)Nc1c(C)c(C)c2c(c1C)CC(C)(C)O2,,C1CCOC1,,CCN(CC)CC,O,test
US04547494,CCOC(=O)/C(=N\OC1CCNC1=O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>O=C(O)/C(=N\OC1CCNC1=O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,CO,,[Na+].[OH-],,test
US20090111760A1,CC1CCc2cc(F)cc3c(=O)c(C(=O)O)cn1c23.NCCN>>CC1CCc2cc(NCCN)cc3c(=O)c(C(=O)O)cn1c23,,CN1CCCC1=O,,,,test
US20080096877A1,CCN=C=NCCCN(C)C.CN(c1cccc2cc(C3=NCC(CC(=O)O)S3)[nH]c12)S(=O)(=O)c1nccs1>>CN(c1cccc2cc(C3=NCC(CC(N)=O)S3)[nH]c12)S(=O)(=O)c1nccs1,,CCOC(C)=O,O,CN(C)C=O,Cl,test
US20060025350A1,CO[C@H]1O[C@@H]2CN(C(=O)OC(=O)c3ccccc3)[C@H]1[C@H]2O.O=C(Cl)c1ccccc1>>CO[C@H]1O[C@@H]2CN(C(=O)OC(=O)c3ccccc3)[C@H]1[C@H]2OC(=O)c1ccccc1,,ClCCl,,Cl,c1ccncc1,test
US20060058361A1,O=S(Cl)Cl.Oc1ccc2occc2c1>>Oc1ccc2occc2c1Cl,,ClCCl,,CCOCC,,test
US20050215556A1,C=CC(C)O.C=CCCOc1nc(NC(=O)Nc2cc(Cl)ccc2O)cnc1C#N>>C=CCCOc1nc(NC(=O)Nc2cc(Cl)ccc2OC(C)C=C)cnc1C#N,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06608072B1,CSc1nccc(I)n1.Fc1ccc(-c2nc3nc(Cl)ccc3[nH]2)cc1>>CSc1nccc(-n2c(-c3ccc(F)cc3)nc3nc(Cl)ccc32)n1,,CN(C)C=O,Cc1ccccc1,,,test
US04785101,CN1C(=O)NCc2ccccc21.COC(=O)CC(C)C(=O)Cl>>COC(=O)CC(C)C(=O)c1ccc2c(c1)CNC(=O)N2C,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20130029962A1,Cc1nc(CO[Si](C)(C)C(C)(C)C)ccc1N.O=C(Cl)Oc1ccccc1>>Cc1nc(CO[Si](C)(C)C(C)(C)C)ccc1NC(=O)Oc1ccccc1,,CC(C)=O,,c1ccncc1,,test
US20060116383A1,CCOC(=O)CC(c1ccccc1)n1cnc2ccc(NC(=O)c3cccc([N+](=O)[O-])c3)cc21>>O=C(O)CC(c1ccccc1)n1cnc2ccc(NC(=O)c3cccc([N+](=O)[O-])c3)cc21,,Cl,,,,test
US20060173004A1,CC(=O)Nc1cc(Cl)ccc1/C=C/C(=O)O.CC1CN(Cc2ccc(Cl)cc2)CCN1>>CC(=O)Nc1cc(Cl)ccc1/C=C/C(=O)N1CCN(Cc2ccc(Cl)cc2)CC1C,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US03956260,CC(C)(C)OC(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CC(N)=O.CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)Oc1ccc([N+](=O)[O-])cc1>>CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)OC(C)(C)C,,CN(C)C=O,,,,test
US20080207639A1,COc1cc(-c2ccccc2C(=O)O)cc(OC)c1OC.O=C(Cl)C(=O)Cl>>COc1cc(-c2ccccc2C(=O)Cl)cc(OC)c1OC,CN(C)C=O,ClCCl,,N#N,,test
US20110312945A1,CCOC(=O)Cn1c(C)c(S(=O)(=O)Cl)c2c1CC(C)(C)CC2=O.CNc1ccccc1>>Cc1c(S(=O)(=O)N(C)c2ccccc2)c2c(n1CC(=O)O)CC(C)(C)CC2=O,,CC(Cl)Cl,,CCN(CC)CC,,test
US20110118236A1,CCOC(=O)CN1CCc2c(C(F)(F)F)nn(CC(=O)Nc3cc(Cl)ccc3OC)c2C1>>COc1ccc(Cl)cc1NC(=O)Cn1nc(C(F)(F)F)c2c1CN(CC(=O)O)CC2,,C1CCOC1,O,CO,[Li+].[OH-],test
US20040192687A1,COC(=O)c1cccc(B(O)O)c1.O=c1cc(Cl)oc(N2CCOCC2)c1>>COC(=O)c1cccc(-c2cc(=O)cc(N3CCOCC3)o2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,N#N,O=C([O-])[O-].[K+].[K+],test
US20120190677A1,CC1(C)CC(c2cc(N3CCOC3=O)ccc2Cl)Nc2ccc(C(=O)O)cc21.NS(=O)(=O)C1CC1>>CC1(C)CC(c2cc(N3CCOC3=O)ccc2Cl)Nc2ccc(C(=O)NS(=O)(=O)C3CC3)cc21,,CN(C)C=O,O,O=C(n1ccnc1)n1ccnc1,[H-].[Na+],test
US20150175602A1,CC(C)N.Fc1ccc(OC2CCN(c3nc4ccncc4nc3Cl)CC2)c(F)c1>>CC(C)Nc1nc2cnccc2nc1N1CCC(Oc2ccc(F)cc2F)CC1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20070066624A1,COC(=O)C(C)C.ICCc1ccccc1>>COC(=O)C(C)(C)CCc1ccccc1,,C1CCOC1,,CN(C)CCN(C)C,[Li]CCCC,test
US20020055505A1,CC(=O)NC[C@H]1CN(c2ccc(C3CCS(=O)(=O)NC3)c(F)c2)C(=O)O1.CI>>CC(=O)NC[C@H]1CN(c2ccc(C3CCS(=O)(=O)N(C)C3)c(F)c2)C(=O)O1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050124654A1,ON=C1CCc2cc(Br)ccc2C1>>NC1CCc2cc(Br)ccc2C1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20130252937A1,C1COCCN1.Cc1cc(C(=O)O)cc(C)c1[N+](=O)[O-]>>Cc1cc(C(=O)N2CCOCC2)cc(C)c1[N+](=O)[O-],,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20090286811A1,COc1cccc(/C=C/c2cc(=O)n3ccsc3n2)c1OCC(C)C.O=C1CCC(=O)N1I>>COc1cccc(/C=C/c2nc3sccn3c(=O)c2I)c1OCC(C)C,,CC#N,,,,test
US05811432,CCOC(=O)CC(=O)OCC.O=[N+]([O-])c1cc(F)cnc1Cl>>O=C1Cc2ncc(F)cc2N1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20100184989A1,CC(C)(C)OC(=O)NNCc1ccc(-c2ccccn2)cc1.CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H]1CO1>>CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CN(Cc1ccc(-c2ccccn2)cc1)NC(=O)OC(C)(C)C,,CC(C)O,,,,test
US04827004,C=C(C)C(=O)CC/C(C)=C/CC/C(C)=C\CO.COC(=O)CS>>COC(=O)CSCC(C)C(=O)CC/C(C)=C/CC/C(C)=C\CO,,CO,,CCN(CC)CC,,test
US20100160388A1,Cc1ccc(S(=O)(=O)n2nc(C)c3cc(Br)c(N=C=O)cc32)cc1.O=C1C=CN[C@H](c2ccc(F)cc2)C1>>Cc1ccc(S(=O)(=O)n2nc(C)c3cc(Br)c(NC(=O)N4C=CC(=O)C[C@H]4c4ccc(F)cc4)cc32)cc1,,C1CCOC1,,[Li]CCCC,,test
US20040127574A1,O=C(O)C(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccncc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>O=C1NC(Cc2ccc(C(F)(F)F)cc2)C(c2ccncc2)O1,,C1CCOC1,,CCN(CC)CC,O,test
US20160152543A1,COC(=O)C(OC(C)(C)C)c1c(C)ccc(OCc2ccccc2)c1-c1ccc2c3c(ccnc13)CCO2>>COC(=O)C(OC(C)(C)C)c1c(C)ccc(O)c1-c1ccc2c3c(ccnc13)CCO2,[Pd],CCOC(C)=O,,[H][H],,test
US20130210803A1,Cc1ccc2c(c1)C(c1ccc(F)cc1)CN2.O=N[O-]>>Cc1ccc2c(c1)C(c1ccc(F)cc1)CN2N=O,,CCO,O,Cl,,test
US20130183269A1,CCOC(=O)C1CCC(F)(F)CC1.CI>>CCOC(=O)C1(C)CCC(F)(F)CC1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20090227625A1,COC(=O)c1ccc2ccccc2c1OCCOc1ccccc1>>O=C(O)c1ccc2ccccc2c1OCCOc1ccccc1,,C1CCOC1,,CO,[Na+].[OH-],test
US20040097518A1,C=CS(=O)(=O)Oc1ccccc1.CC(C)[C@H](NC(=O)c1c(CN2CCNCC2)c(-c2ccccc2)nc2ccccc12)c1ccccc1>>CC(C)[C@H](NC(=O)c1c(CN2CCN(CCS(=O)(=O)Oc3ccccc3)CC2)c(-c2ccccc2)nc2ccccc12)c1ccccc1,,ClCCl,,,,test
US04596666,CO.Nc1c(C(=O)Oc2ccccc2)cc([N+](=O)[O-])c2c1C(=O)c1ccccc1C2=O.Sc1ccc(Cl)cc1>>COC(=O)c1cc(Sc2ccc(Cl)cc2)c2c(c1N)C(=O)c1ccccc1C2=O,,CO,,CN1CCCC1=O,O=C([O-])[O-].[K+].[K+],test
US05853930,COc1cc([N+](=O)[O-])cc(C=O)c1O.O=[N+]([O-])c1ccc(CBr)cc1>>COc1cc([N+](=O)[O-])cc2cc(-c3ccc([N+](=O)[O-])cc3)oc12,,C1COCCO1,,C1CCC2=NCCCN2CC1,,test
US20070066820A1,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc(OCc2ccccc2)cc1.Cl>>Cl.c1ccc(COc2ccc(OC[C@H]3CCCN3)cc2)cc1,,C1COCCO1,,,,test
US20050234238A1,CC(C)(c1cc(-c2cccc(-c3ccc(OCc4ccccc4)nc3)c2)c2ncccc2c1)S(C)(=O)=O>>CC(C)(c1cc(-c2cccc(-c3ccc(=O)[nH]c3)c2)c2ncccc2c1)S(C)(=O)=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140275130A1,COc1ccncc1NC(=O)c1c(N)nn2cc3c(nc12)CCN(C(=O)OC(C)(C)C)C3>>COc1ccncc1NC(=O)c1c(N)nn2cc3c(nc12)CCNC3,,ClCCl,,O=C(O)C(F)(F)F,,test
US04132746,COC(=O)CNC(=O)[C@H](CC(OC(C)(C)C)C(=O)O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C>>CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC(OC(C)(C)C)C(=O)O)C(=O)NCC(=O)O,,CO,,[Na+].[OH-],,test
US04026891,Nc1ccc(C2=NNC(=O)CC2)cc1[N+](=O)[O-]>>Nc1ccc(C2=NNC(=O)CC2)cc1N,O=[Pt]=O,CCO,,,,test
US06133287,CCCCC([SnH3])=C(CCCC)CCCC.CN(C)C=O.CN1CC=C(c2cn(C(=O)c3ccccc3)c3ccc(Br)cc23)CC1>>C=Cc1ccc2c(c1)c(C1=CCN(C)CC1)cn2C(=O)c1ccccc1.N,,CN(C)C=O,,,,test
US05705499,C=Cc1ccc2ccccc2c1.CCN1c2ncc(Br)cc2C(=O)N(C)c2ccc(F)nc21>>CCN1c2ncc(CCc3ccc4ccccc4c3)cc2C(=O)N(C)c2ccc(F)nc21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,CCN(C(C)C)C(C)C,,test
US04959361,C#Cc1ccccn1.Cc1nnc2n1-c1sc(I)cc1C(c1ccccc1Cl)=NC2>>Cc1nnc2n1-c1sc(C#Cc3ccccn3)cc1C(c1ccccc1Cl)=NC2,,ClCCl,,CCO,,test
US20130178413A1,CCOC(=O)Cl.Nc1cc(Cl)ccc1C(=O)O>>CCOC(=O)Nc1cc(Cl)ccc1C(=O)O,,C1CCOC1,,,,test
US20050245554A1,CSc1ncc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1.OCc1ccc(F)c(F)c1>>Fc1ccc(COc2ncc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)n2)cc1F,,CCCCCC,CCOC(C)=O,,,test
US04501890,CN(C)C(N(C)C)N(C)C.N#CN1CCC[C@@H]2CC(=O)CC[C@H]21>>CN(C)C=C1C[C@@H]2[C@H](CCCN2C#N)CC1=O,,Cc1ccccc1,,,,test
US20040058903A1,CC(C)(C)OC(=O)N(CCc1ccccn1)c1ccc(NC(=O)c2ccccc2-c2ccc(OCc3ccccc3)cc2)cc1>>CC(C)(C)OC(=O)N(CCc1ccccn1)c1ccc(NC(=O)c2ccccc2-c2ccc(O)cc2)cc1,[Pd],CO,,[H][H],,test
US20050130057A1,C=COCC.O=Cc1ccc(O)cc1>>CCOCCOc1ccc(C=O)cc1,,CCOC(C)=O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20130116234A1,CC(C)(C)OC(=O)c1c(O)nc2ccc(Cl)cc2c1-c1cccc(Cl)c1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)c1c(OS(=O)(=O)C(F)(F)F)nc2ccc(Cl)cc2c1-c1cccc(Cl)c1,,CN(C)C=O,,[H-].[Na+],,test
US05292734,CCCCc1nc(=O)c2cc(C=O)ccc2[nH]1.CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCc1nc(=O)c2cc(C=CC(=O)OCC)ccc2[nH]1,,CC#N,,,,test
US20030139442A1,N#Cc1cc(Br)ccc1N.O=C1CCCN1Cc1ccccc1>>Nc1c2c(nc3ccc(Br)cc13)N(Cc1ccccc1)CC2,,ClC(Cl)Cl,,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US20130165476A1,CCC(C)(C)C(=O)Oc1cc2c(s1)CCN([C@H](C(=O)OC)c1ccccc1Cl)C2.Cl>>CCC(C)(C)C(=O)Oc1cc2c(s1)CCN([C@H](C(=O)OC)c1ccccc1Cl)C2.Cl,,CCOCC,,,,test
US04061656,BrP(Br)Br.CCOC(=O)C=C(C)C=CC=C(C)CO>>CCOC(=O)C=C(C)C=CC=C(C)CBr,c1ccncc1,CCCCCC,,CCOCC,,test
US05563174,CCOC(=O)CCN(SN(CCC(=O)OCC)C(C)(C)Cl)C(C)(C)Cl.CCOC(=O)NN=C(c1ccc(Cl)cc1)c1ccc(OS(=O)(=O)C(F)(F)F)cc1>>CCOC(=O)CCN(SN(N=C(c1ccc(Cl)cc1)c1ccc(OS(=O)(=O)C(F)(F)F)cc1)C(=O)OCC)C(C)C,,C1CCOC1,,[H][H],[H-].[Na+],test
US05216015,CCC(C)(C)C(=O)O[C@H]1C[C@H]2[C@@H](CC[C@@H]3C[C@H](O[Si](C)(C)C(C)(C)C)CC[C@]23C)[C@@H]2CCC(=O)[C@@]12C.C[Si](C)(C)Cl>>CCC(C)(C)C(=O)O[C@H]1C[C@H]2[C@@H](CC[C@@H]3C[C@H](O[Si](C)(C)C(C)(C)C)CC[C@]23C)[C@@H]2CC=C(O[Si](C)(C)C)[C@@]12C,,C1CCOC1,CCCCCC,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20100174065A1,CCOC(=O)CCCN1CCc2ccc(-c3noc(-c4cnc(OC(C)C)c(Cl)c4)n3)cc2CC1>>CC(C)Oc1ncc(-c2nc(-c3ccc4c(c3)CCN(CCCC(=O)O)CC4)no2)cc1Cl,,CCO,,CC(=O)O,[Na+].[OH-],test
US20080114007A1,CCOC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(S(C)(=O)=O)ncc2c1=O.CN1CCN(CCc2ccc(N)cc2)CC1>>C#Cc1ccc(-n2cc(C(=O)OCC)c(=O)c3cnc(Nc4ccc(CCN5CCN(C)CC5)cc4)nc32)cc1,,CC(C)O,,,,test
US20090227803A1,CC(=O)Oc1ccc(Cl)cc1/C=C/c1ccccc1Br.COCN(Cc1ccccc1)C[Si](C)(C)C>>CC(=O)Oc1ccc(Cl)cc1[C@@H]1CN(Cc2ccccc2)C[C@H]1c1ccccc1Br,O=C(O)C(F)(F)F,Cc1ccccc1,,O,,test
US05604237,COc1ccc2c(c1)CCNC2.O=[N+]([O-])c1ccc(CCBr)cc1>>COc1ccc2c(c1)CCN(CCc1ccc([N+](=O)[O-])cc1)C2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06218135B1,COc1cccc(COCC(C)(C)C(O)C(C)(C)C)c1>>COc1cccc(COCC(C)(C)C(=O)C(C)(C)C)c1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20040010127A1,CC(C)(Cl)C(Cc1c[nH]c([N+](=O)[O-])n1)N=O.CC(CN)CN>>CC(CN)CNC(C)(C)C(Cc1c[nH]c([N+](=O)[O-])n1)=NO,,CC#N,,,,test
US20080021064A1,COc1ccc2nccc(C)c2c1.O=C1CCC(=O)N1Br>>COc1ccc2nccc(CBr)c2c1,,c1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20040010017A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)c1ccc2cc[nH]c2c1>>CC(C)(C)OC(=O)n1ccc2ccc(C(=O)O)cc21,CN(C)c1ccncc1,CC#N,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20140018400A1,O=C(Cl)c1ccc(Br)cc1.OC[C@@H]1CSC(c2ccccc2O)=N1>>O=C(OC[C@@H]1CSC(c2ccccc2O)=N1)c1ccc(Br)cc1,,ClCCl,,CCN(CC)CC,,test
US20090181957A1,CC(C)(C)[C@H](NC(=O)OCc1ccccc1)C(N)=O>>CC(C)(C)[C@H](N)C(N)=O,[Pd],C1CCOC1,,,,test
US20150031674A1,CCOC(=O)Cn1c(=O)c(-c2ccc(-c3cncc(C)n3)cc2Cl)cc2cnc(SC)nc21.CN>>CCOC(=O)Cn1c(=O)c(-c2ccc(-c3cncc(C)n3)cc2Cl)cc2cnc(NC)nc21,,C1CCOC1,,O=C(OO)c1cccc(Cl)c1,,test
US20080287517A1,C=CCBr.Cc1c(C(=O)Nc2ccc(F)c(F)c2O)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(O)cc1>>C=CCOc1c(NC(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(O)cc3)c2C)ccc(F)c1F,,CC#N,ClCCl,O,O=C([O-])[O-].[Cs+].[Cs+],test
US08138168B1,COCCCn1c([C@@H]2CCCN(C(=O)OC(C)(C)C)C2)nc2ccncc21>>COCCCn1c([C@@H]2CCCNC2)nc2ccncc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130158066A1,CCOC(=O)n1c(OS(=O)(=O)C(F)(F)F)cc2nc(Cl)ccc21.COc1cc(F)c(B(O)O)c(F)c1>>COc1cc(F)c(-c2cc3nc(Cl)ccc3[nH]2)c(F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,O,Cc1ccccc1,O=C([O-])O.[Na+],test
US20130190347A1,CCOC(=O)CC1C=C2C=C(C)N=CC23NC(C)CC3C1>>CC1=CC2=CC(CC(=O)O)CC3CC(C)NC23C=N1,,CCO,,Cl,[Na+].[OH-],test
US04772600,CN.O=C(O)Cn1c(-c2ccc(F)cc2)nc2cccnc21>>CNC(=O)Cn1c(-c2ccc(F)cc2)nc2cccnc21,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US05916905,CCCCOc1nc(-c2ccc(F)cc2)c(-c2ccc(S(C)(=O)=O)cc2)cc1C=O.CN>>CCCCOc1nc(-c2ccc(F)cc2)c(-c2ccc(S(C)(=O)=O)cc2)cc1CNC,,CO,,Cl,,test
US20080139607A1,CC(C)C(=O)Cl.COC(=O)[C@@H]1CSc2c(-c3ccccc3)c(Cc3cccc4ccccc34)c(N)c(=O)n21>>COC(=O)[C@@H]1CSc2c(-c3ccccc3)c(Cc3cccc4ccccc34)c(NC(=O)C(C)C)c(=O)n21,,c1ccncc1,,ClCCl,,test
US20050014753A1,NCCN1CCOCC1.O=C(O)c1ccc(-c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2)cc1>>O=C(NCCN1CCOCC1)c1ccc(-c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06441017B1,CC(C)(C)OC(=O)Nc1c(Br)ccc2ccc(OS(C)(=O)=O)cc12>>CC(C)(C)OC(=O)Nc1c(Br)ccc2ccc(O)cc12,,CS(C)=O,O,Cl,CC(C)(C)[O-].[K+],test
US06495723B1,Nc1ccccc1.O=[N+]([O-])c1ccccc1>>c1ccc2nc3ccccc3nc2c1,,O,,,,test
US20150087646A1,COc1cc(-n2nc(-c3cc(CNC(=O)C(F)(F)F)ccc3Cl)[nH]c2=O)ccc1[N+](=O)[O-]>>COc1cc(-n2nc(-c3cc(CN)ccc3Cl)[nH]c2=O)ccc1[N+](=O)[O-],,[K+],[OH-],,,test
US20110224391A1,CC(C)(C)OC(=O)Nc1ccccc1.[Li]CCCC>>[Li]N(C(=O)OC(C)(C)C)c1ccccc1,,CCCCC,,,,test
US05955610,CCOP(=O)(OCC)[C@H]1CC[C@H](CBr)O1.Nc1nc(Cl)c2[nH]cnc2n1>>CCOP(=O)(OCC)[C@H]1CC[C@H](Cn2cnc3c(Cl)nc(N)nc32)O1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130029986A1,COC(=O)C(C(=O)OC)c1ncccc1[N+](=O)[O-]>>Cc1ncccc1[N+](=O)[O-],,Cl,,,,test
US20110087030A1,CC(C#N)C(O)(Cn1cncn1)c1cc(F)ccc1F.CC1(C)C2CC[C@]1(CS(=O)(=O)O)C(=O)C2>>CC1(C)C2CC[C@]1(CS(=O)(=O)[O-])C(=O)C2.C[C@@H](C#N)[C@](O)(Cn1cncn1)c1cc(F)ccc1F,,CC(C)=O,CO,,,test
US20070225288A1,CCOC(=O)C1=C(c2ccccc2)c2ccc(OCCCc3ccccc3)cc2C1=O.Cl[Mg]c1ccccc1>>CCOC(=O)C1=C(c2ccccc2)c2ccc(OCCCc3ccccc3)cc2C1(O)c1ccccc1,,C1CCOC1,,,,test
US20120295966A1,COc1cc(C=O)ccc1OC(C)=O.O=C(OO)c1cccc(Cl)c1>>COc1cc(OC=O)ccc1OC(C)=O,,ClCCl,,,,test
US05977134,N#Cc1ccc(Cn2cncc2CCl)cc1.Nc1nc2ccccc2[nH]1>>N#Cc1ccc(Cn2cncc2CC2(N)N=c3ccccc3=N2)cc1,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20080242663A1,CI.Cc1cccc(CO)c1Nc1ccnc(Cl)n1>>Cc1cccc(CO)c1N(C)c1ccnc(Cl)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050049252A1,CCOC(=O)/C=C/C(F)(F)F.O=Cc1c(O)ccc2ccccc12>>CCOC(=O)C1=C(C(F)(F)F)COc2ccc3ccccc3c21,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20020099212A1,C[Si](C)(C)CCOCCl.Cc1nc(Br)c(Br)[nH]1>>Cc1nc(Br)c(Br)n1COCC[Si](C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20080113966A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)Cn2c(C(O)C3CC3)cnc21.CI>>COC(c1cnc2n1C[C@H](c1cccc(F)c1F)CC[C@H]2NC(=O)OC(C)(C)C)C1CC1,,C1CCOC1,,[H-].[Na+],,test
US20070105904A1,Cc1cccc(F)n1.OCc1ccc(Br)cc1>>Cc1cccc(OCc2ccc(Br)cc2)n1,,CN(C)C=O,,[H-].[Na+],,test
US05134128,CI.C[Si](C)(C)c1cc(C(O)CCCc2ccccc2)co1>>COC(CCCc1ccccc1)c1coc([Si](C)(C)C)c1,,C1CCOC1,,[H-].[Na+],,test
US20110275638A1,CC(C)(C)OC(=O)N1CCN(CCO)CC1.COC(=O)[C@@](C)(N)Cc1ccc(O)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COC(=O)[C@](C)(Cc1ccc(O)cc1)NC(=O)OCCN1CCN(C(=O)OC(C)(C)C)CC1,CN(C)c1ccncc1,ClCCl,,Cl,,test
US20090291993A1,CC(C)(C)c1ccc(CBr)cc1.COC(=O)c1ccc(CCC(/C=C/c2ccccc2O)Cc2cc(F)c(O[Si](C(C)C)(C(C)C)C(C)C)c(F)c2)cc1>>COC(=O)c1ccc(CCC(/C=C/c2ccccc2OCc2ccc(C(C)(C)C)cc2)Cc2cc(F)c(O[Si](C(C)C)(C(C)C)C(C)C)c(F)c2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05393431,CCC(C)[Mg]Cl.CCOCC.ClP(Cl)Cl>>CCC(C)P(Cl)C(C)CC,,CCOCC,,,,test
US03951967,CC(C)Sc1cc(S(N)(=O)=O)c(N)cc1Cl.O=C(Cl)CCl>>CC(C)Sc1cc2c(cc1Cl)N=C(CCl)NS2(=O)=O,,C1COCCO1,,O,CC(=O)[O-].[K+],test
US04954508,CCOC(=O)C(=Cc1ccccc1C)C(C)=O.Cl.Cn1nc(-c2ccccc2)cc1N>>CCOC(=O)C1=C(C)Nc2c(c(-c3ccccc3)nn2C)C1c1ccccc1C.Cl,,CCO,,CO,,test
US20050107449A1,CCc1nc(-c2ccc(C(F)(F)F)cc2)oc1C(=O)OC>>CCc1nc(-c2ccc(C(F)(F)F)cc2)oc1CO,,C1CCOC1,,[BH4-].[Li+],,test
US20160108037A1,O=C(O)c1ccc(C(F)(F)F)n2cnnc12.O=C1CCC(=O)N1Cl>>O=C(O)c1ccc(C(F)(F)F)n2c(Cl)nnc12,,CN(C)C=O,,,,test
US20060069110A1,CN(c1ccnc(Cl)n1)c1ccnc(NCCc2cccnc2)n1.OB(O)c1ccsc1>>CN(c1ccnc(NCCc2cccnc2)n1)c1ccnc(-c2ccsc2)n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US05420119,COc1ccc(CS[C@H]2C[C@@H](C(=O)N3CCN(CCO)CC3)N(C(=O)OCc3ccc([N+](=O)[O-])cc3)C2)cc1.O=C=NC(=O)C(Cl)(Cl)Cl>>COc1ccc(CS[C@H]2C[C@@H](C(=O)N3CCN(CCOC(N)=O)CC3)N(C(=O)OCc3ccc([N+](=O)[O-])cc3)C2)cc1,,ClCCl,,,,test
US20130158025A1,CC(N)O.CCOCc1nn2c(-c3ccc(F)cc3)cc(Cl)nc2c1-c1ccc(C)cc1>>CCOCc1nn2c(-c3ccc(F)cc3)cc(NCCO)nc2c1-c1ccc(C)cc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20100056576A1,CC1CC(c2ccncc2[N+](=O)[O-])=CC(O[Si](C)(C)C(C)(C)C)C1>>CC1CC(O[Si](C)(C)C(C)(C)C)CC(c2ccncc2N)C1,[Pd],CO,,,,test
US20060211717A1,COc1cc2nccc(Oc3ccc(N)cc3Cl)c2cc1OC.Cc1cccc(C(=O)N=C=S)c1>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4cccc(C)c4)cc3Cl)c2cc1OC,,Cc1ccccc1,,CCO,,test
US20110263863A1,Clc1ccc2nsnc2c1NC1=NCCN1.O=CO>>Clc1ccc2nsnc2c1NC1=NCCN1.O=C[O-],,CC(C)O,,,,test
US04596816,CCOC(=O)CC(=O)OCC.Cc1nc(-c2ccccc2)c(CBr)o1>>CCOC(=O)C(Cc1oc(C)nc1-c1ccccc1)C(=O)OCC,,CN(C)C=O,O,[H-].[Na+],,test
US20100055608A1,C=C(C)C(=O)Oc1ccc2cc(C(=O)Cl)ccc2c1.O=S(=O)([O-])C(F)(F)C(O)C(F)(F)F.c1ccc([S+](c2ccccc2)c2ccccc2)cc1>>C=C(C)C(=O)Oc1ccc2cc(C(=O)OC(C(F)(F)F)C(F)(F)S(=O)(=O)[O-])ccc2c1.c1ccc([S+](c2ccccc2)c2ccccc2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20130345203A1,CCOC(=O)c1cc(O[Si](C)(C)C(C)(C)C)nn1CCNC(=O)OC(C)(C)C>>CCOC(=O)c1cc(O)nn1CCNC(=O)OC(C)(C)C,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120040954A1,Cc1cc(C=O)cc(C)c1O.OCCCCBr>>Cc1cc(C=O)cc(C)c1OCCCCO,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US05731344,O=c1cc(OCc2ccccc2)cc(CC(O)c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)o1>>O=c1cc(O)cc(CC(O)c2ccc(O)c(O)c2)o1,[Ni],CCO,,[H][H],,test
US20080027070A1,N#Cc1ccc(C(=O)Cl)cc1.Nc1ccc(Cl)c(C(=O)O)c1>>N#Cc1ccc(C(=O)Nc2ccc(Cl)c(C(=O)O)c2)cc1,,C1CCOC1,,,,test
US20120157454A1,CN.O=C(CCl)Nc1ccc2[nH]c(=O)c3ccccc3c2c1>>CNCC(=O)Nc1ccc2[nH]c(=O)c3ccccc3c2c1,,CCO,CN(C)C=O,,,test
US05187192,Brc1cccs1.Oc1ccc(F)cc1>>Fc1ccc(Oc2cccs2)cc1,[Cu],c1ccncc1,,O=C([O-])[O-].[K+].[K+],,test
US20090298836A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H](N)[C@@H](O[Si](C)(C)C(C)(C)C)c1ccc(C(F)(F)F)cc1>>COC(=O)[C@@H](NC(=O)OC(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)c1ccc(C(F)(F)F)cc1,,C1CCOC1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20140371240A1,Cn1nc(C(F)(F)C(F)(F)F)c(C(F)(F)F)c1C(=O)O.N#Cc1c(F)ccc(N)c1F>>Cn1nc(C(F)(F)C(F)(F)F)c(C(F)(F)F)c1C(=O)Nc1ccc(F)c(C#N)c1F,CN(C)C=O,C1CCOC1,ClCCl,O=C(Cl)C(=O)Cl,c1ccncc1,test
US04391818,CCC(C(=O)O)c1ccccc1.O=[N+]([O-])O>>CCC(C(=O)O)c1ccc([N+](=O)[O-])cc1,,O=S(=O)(O)O,,CC(=O)O,,test
US20080227839A1,CON(C)C(=O)c1ccc([N+](=O)[O-])c(NC2CCCC2)c1>>CON(C)C(=O)c1ccc(N)c(NC2CCCC2)c1,,CCO,,O=C[O-].[NH4+],,test
US20050107339A1,CCOP(=O)(CC#N)OCC.CCOc1cc(C(=O)c2ccc(OC)c(C)c2)ccc1OC>>CCOc1cc(C(=CC#N)c2ccc(OC)c(C)c2)ccc1OC,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20070032515A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)CNCc1ccccc1>>CCOC(=O)CN(Cc1ccccc1)C(=O)OC(C)(C)C,,C1CCOC1,,,,test
US20110028493A1,CCOC(=O)c1ccc(Br)s1.OB(O)c1cccc(C(F)(F)F)c1>>CCOC(=O)c1ccc(-c2cccc(C(F)(F)F)c2)s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20040110804A1,CO.CON(Cc1cccc(F)c1)C(=O)C=C1OC(C)(C)OC1=O>>COC(=O)C(O)=CC(=O)N(Cc1cccc(F)c1)OC,,CO,,,,test
US20070197551A1,COC(=O)CCCC(C)N1CCN(c2ccc3ccccc3n2)CC1>>CC(CCCC(=O)O)N1CCN(c2ccc3ccccc3n2)CC1,,CCO,,Cl,[Na+].[OH-],test
US20100160255A1,CCOC(=O)c1c(N)sc2c1CCSC2>>Nc1sc2c(c1C(=O)O)CCSC2,,CCOC(C)=O,,,,test
US20040157836A1,C[Si](C)(C)C=[N+]=[N-].Nc1ccc2ccccc2c1C(=O)O>>Cc1cc2ccccc2c(C(=O)O)c1N,,CO,c1ccccc1,,,test
US20130336949A1,BrC(Br)(Br)Br.Cc1cccc(C)c1COc1cccc(CO)c1C>>Cc1cccc(C)c1COc1cccc(CBr)c1C,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20120142668A1,COC(=O)/C=C/[C@H](CCc1ccccc1)NC(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>COC(=O)/C=C/[C@@H](N)CCc1ccccc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US04552882,CCBr.CCOC(=O)c1cnc2cc(NC(C)=O)ccc2c1O>>CCn1cc(C(=O)O)c(=O)c2ccc(N)cc21,,[Na+],[OH-],CCO,O,test
US20160000760A1,CI.Fc1ccc(-c2c(Cl)cc(N=C=S)cc2Cl)cc1.N#CN>>CS/C(=N\C#N)Nc1cc(Cl)c(-c2ccc(F)cc2)c(Cl)c1,,CO,,C[O-].[Na+],,test
US20080214563A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.COC(=O)c1sc(-n2cnc3cc(Br)ccc32)cc1O[C@H](C)c1ccccc1Cl>>COC(=O)c1sc(-n2cnc3cc(-c4cn[nH]c4)ccc32)cc1O[C@H](C)c1ccccc1Cl,,CC(=O)N(C)C,,O=C([O-])[O-].[Na+].[Na+],,test
US20130137675A1,CC(=O)c1nn(-c2cccc(C(F)(F)F)c2)c2ccoc2c1=O>>CC(O)c1nn(-c2cccc(C(F)(F)F)c2)c2c(c1=O)OCC2,[Pd],CO,,,,test
US20080319016A1,NC(=NO)c1ccc(OCCCC2CCN(CCCOc3ccc(C(N)=NC(=O)[O-])cc3)CC2)cc1>>N=C(N)c1ccc(OCCCN2CCC(CCCOc3ccc(C(N)=NO)cc3)CC2)cc1,,CCO,,Cl,,test
US20060217380A1,Cc1cc(N)ccc1I.O=C(Cl)c1cccc(C(F)(F)F)c1>>Cc1cc(NC(=O)c2cccc(C(F)(F)F)c2)ccc1I,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110201593A1,COCC(=O)Cl.Cc1nocc1CC(=O)Nc1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1NC1CCNCC1>>COCC(=O)N1CCC(Nc2c(NC(=O)Cc3conc3C)cnc3c2ccn3S(=O)(=O)c2ccccc2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040006141A1,CCCCC(Cc1ccc(OCCCN=[N+]=[N-])cc1)C(=O)OCC>>CCCCC(Cc1ccc(OCCCN)cc1)C(=O)OCC,[Pd],,,,,test
US20150210677A1,NC1=C(O)C(=O)C(c2cccc(Cl)c2Cl)O1.O=S(=O)(Cl)Cc1ccccc1>>NC1=C(OS(=O)(=O)Cc2ccccc2)C(=O)C(c2cccc(Cl)c2Cl)O1,,C1CCOC1,,CCN(CC)CC,[Cl-].[NH4+],test
US20080287478A1,O=C1N(CCCOCc2ccccc2)CN(c2ccccc2)C12CCNCC2>>O=C1N(CCCOCc2ccccc2)CN(c2ccccc2)C12CCNCC2,,[Na+],[OH-],CCOC(C)=O,Cl,test
US05677302,CN1CCN(c2nsc3nc4ccccc4n23)CC1.Cl.ClCCl>>CN1CCN(c2nsc3nc4ccccc4n23)CC1.Cl.Cl,,Cl,,,,test
US20030216417A1,COc1cc2ncnc(Nc3cccc(N)c3)c2cc1OC.COc1cccc(C(=O)Cl)c1>>COc1cccc(C(=O)Nc2cccc(Nc3ncnc4cc(OC)c(OC)cc34)c2)c1.Cl,,ClCCl,,,,test
US20140018319A1,CCNc1nc(Nc2cc(C#N)cc(N3CCC(N)CC3)c2Cl)nn2c(C#N)cnc12.COC(=O)Cl>>CCNc1nc(Nc2cc(C#N)cc(N3CCC(NC(=O)OC)CC3)c2Cl)nn2c(C#N)cnc12,,C1CCOC1,CO,CCN(C(C)C)C(C)C,,test
US20030069271A1,CC(C)CC(=O)Cl.CCOC(=O)c1cnccc1N>>CCOC(=O)c1cnccc1NC(=O)CC(C)C,,CCOCC,,CCN(CC)CC,O,test
US20040209901A1,Cc1cc(F)ccc1-c1nc(S(C)(=O)=O)nc2c1ccc(=O)n2-c1ccccc1F.NC1CCCCC1>>Cc1cc(F)ccc1-c1nc(NC2CCCCC2)nc2c1ccc(=O)n2-c1ccccc1F,,C1CCOC1,,,,test
US20130211076A1,Clc1nc2ccccc2nc1Cl.NS(=O)(=O)c1ccc(F)cc1>>O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccc(F)cc1,,CC(=O)N(C)C,,Cl,[Li+].[OH-],test
US20080214641A1,CC(N)C(Oc1ccc2c(cnn2-c2ccccn2)c1)c1ccccc1.COCC(=O)Cl>>COCC(=O)NC(C)C(Oc1ccc2c(cnn2-c2ccccn2)c1)c1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20010047038A1,Nc1ccccc1CSc1nc2ccccc2[nH]1.O=C(OO)c1cccc(Cl)c1>>Nc1ccccc1CS(=O)c1nc2ccccc2[nH]1,,ClC(Cl)Cl,,,,test
US20150274704A1,C=C1CC(=O)O1.NCc1ccccc1>>CC(=O)CC(=O)NCc1ccccc1,,ClCCl,,,,test
US20030073728A1,CCOP(=O)(OCC)c1ccco1.COC=O>>CCOP(=O)(OCC)c1ccc(C=O)o1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US04735940,CN(C)C(OC(C)(C)C)OC(C)(C)C.O=C(O)c1cc(-c2cccc(F)c2)c(=O)n2c1-c1sccc1CC2>>CC(C)(C)OC(=O)c1cc(-c2cccc(F)c2)c(=O)n2c1-c1sccc1CC2,,Cc1ccccc1,,,,test
US20160120850A1,CCOC(=O)c1nc(CC2CCC2)cs1.N>>NC(=O)c1nc(CC2CCC2)cs1,,CO,,,,test
US04673684,COCCOCOc1ccc(C=CC(=O)O)cc1OCOCCOC.Nc1ccccc1O>>COCCOCOc1ccc(C=CC(=O)Nc2ccccc2O)cc1OCOCCOC,,CC#N,O,CCN(CC)CC,C[n+]1ccccc1Cl.[I-],test
US20060160794A1,COC(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1N.COc1ccc(OC)o1>>COC(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-n1cccc1,,CC(=O)O,O,,,test
US05331006,COC(=O)c1c[nH]c(C)c1C.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1cn(S(=O)(=O)c2ccc(C)cc2)c(C)c1C,,C1CCOC1,,O,[Na+].[OH-],test
US20050272732A1,CCC(NC(C)=O)c1nnc(C2CCCO2)[nH]c1=O>>CCC(N)c1nnc(C2CCCO2)[nH]c1=O,,Cl,,CCO,[Na+].[OH-],test
US20160122342A1,CC=O.COC(=O)c1cccc(NC2CCC(F)(F)CC2)c1Br>>CCN(c1cccc(C(=O)OC)c1Br)C1CCC(F)(F)CC1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US06340687B1,CCNCCCNc1ccc(Cl)cc1C.S=C(n1ccnc1)n1ccnc1>>CCN1CCCN(c2ccc(Cl)cc2C)C1=S,,C1COCCO1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20120295887A1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.CCOC(=O)c1c(C=O)[nH]c(C(=O)OC(C)(C)C)c1C>>CCOC(=O)C=Cc1[nH]c(C(=O)OC(C)(C)C)c(C)c1C(=O)OCC,,C1CCOC1,,,,test
US20030153577A1,CC(C)[C@H](N)CN1CCC(Cc2ccc(Cl)c(Cl)c2)CC1.Cc1ccc(C(=O)Cl)cc1>>Cc1ccc(C(=O)N[C@H](CN2CCC(Cc3ccc(Cl)c(Cl)c3)CC2)C(C)C)cc1,,c1ccncc1,,,,test
US05176739,CC(C)c1nc(C(=O)NC2CC2)co1.O=C=O>>CC(C)c1nc(C(=O)NC2CC2)c(C(=O)O)o1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20060258659A1,CCCC/C=N/n1cccc1>>CCCCCNn1cccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060205670A1,CC(=O)CC(=O)CCc1ccc([N+](=O)[O-])cc1.O=C1CCCC(=O)O1>>CC(=O)CC(=O)CCc1ccc(NC(=O)CCCC(=O)O)cc1,,C1CCOC1,,,,test
US20090131689A1,CCCCCC(CC1Cc2cc(F)c(F)cc2C1=O)C(=O)OC>>CCCCCC(CO)CC1Cc2cc(F)c(F)cc2C1O,,C1CCOC1,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20100099695A1,C=CCCC(C)(C)COC(=O)N[C@H](C(=O)N1C[C@H](NC(=O)c2cc3c(Br)cccc3n2C)C[C@H]1C(=O)OC)C(C)(C)C.CCCCC([Sn])=C(CCCC)CCCC>>C=CCCC(C)(C)COC(=O)N[C@H](C(=O)N1C[C@H](NC(=O)c2cc3c(C=C)cccc3n2C)C[C@H]1C(=O)OC)C(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,N#N,,test
US20150315198A1,Cc1c(CNc2ncnc3nn(Cc4ccc(Cn5ccccc5=O)cc4)cc23)c(F)cc2c1CN(C(=O)OC(C)(C)C)C2>>Cc1c(CNc2ncnc3nn(Cc4ccc(Cn5ccccc5=O)cc4)cc23)c(F)cc2c1CNC2,,C1COCCO1,,Cl,,test
US20140046074A1,CC[C@@H](c1cccc(OC)c1)[C@@H](C)CN(C)C.Cl>>CC[C@@H](c1cccc(O)c1)[C@@H](C)CN(C)C.Cl,,ClCCl,,BrB(Br)Br,CO,test
US06448270B1,O=S(=O)(c1ccccc1)n1ccc2cc(C#CCCN3CCC(Cc4ccccc4)CC3)ccc21>>C(#Cc1ccc2[nH]ccc2c1)CCN1CCC(Cc2ccccc2)CC1,,CCO,,[Na+].[OH-],,test
US20120214837A1,CNc1nc2cc3c(cc2cc1CO)OCO3.ClCCl.O=S(Cl)Cl>>CNc1nc2cc3c(cc2cc1CCl)OCO3.Cl,,ClCCl,,,,test
US20120041026A1,CC1(C)OC(=O)c2c(O)cccc2O1.O[C@H]1CCOC1>>CC1(C)OC(=O)c2c(O[C@@H]3CCOC3)cccc2O1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090156642A1,CN(Cc1cc(-c2cccnc2F)c(S(=O)(=O)c2ccccc2)s1)C(=O)OC(C)(C)C.Cl>>CNCc1cc(-c2cccnc2F)c(S(=O)(=O)c2ccccc2)s1.Cl,,CC(C)O,CCOC(C)=O,,,test
US20080312226A1,CC(C)(C)OC(=O)N1CCNCC1.Clc1ccccc1-c1csc(Br)n1>>CC(C)(C)OC(=O)N1CCN(c2nc(-c3ccccc3Cl)cs2)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160009667A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1noc2cc(COc3ccc(Cl)c(Cl)c3)c(C3CC3)cc12>>Nc1noc2cc(COc3ccc(Cl)c(Cl)c3)c(C3CC3)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US04315006,CCOC1=CC(=O)CC(c2ccccc2O)C1.COCCOCCl>>CCOC1=CC(=O)CC(c2ccccc2OCOCCOC)C1,,C1CCOC1,,[H-].[Na+],,test
US20150218181A1,COc1cc(-c2cnc(C)n2C)ccc1Nc1cc2cc(-c3cnn(CC4COC(C)(C)O4)c3)ccc2cn1>>COc1cc(-c2cnc(C)n2C)ccc1Nc1cc2cc(-c3cnn(CC(O)CO)c3)ccc2cn1,,C1CCOC1,,O=C(O)C(F)(F)F,,test
US04960784,CS(=O)(=O)Cl.O=C1c2ccccc2CCC1(CO)c1ccc(Cl)cc1>>CS(=O)(=O)OCC1(c2ccc(Cl)cc2)CCc2ccccc2C1=O,,C1CCOC1,,CCN(CC)CC,,test
US20020156311A1,CCOC(=O)C1CCCCN1.Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccc(Oc2cccc(OCCOS(C)(=O)=O)c2)cc1>>CCOC(=O)C1CCCCN1CCOc1cccc(Oc2ccc(CN(Cc3ccccc3)c3cccc(NS(C)(=O)=O)c3C)cc2)c1,,CCOC(C)=O,CN(C)C=O,,,test
US20030119173A1,CC#N.O=C(Cl)c1ccccc1Cl>>N#CC(=O)c1ccccc1Cl,,Cc1ccccc1,,,,test
US20140155391A1,COc1ccc(CNS(C)(=O)=O)cc1C(=O)O.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>COc1ccc(CNS(C)(=O)=O)cc1C(=O)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20060270874A1,NS(=O)(=O)C=Cc1ccccc1.O=C(Cl)c1ccc(Cl)cc1F>>O=C(NS(=O)(=O)C=Cc1ccccc1)c1ccc(Cl)cc1F,,C1COCCO1,,Cl,O,test
US20090048320A1,CCN(CC)S(F)(F)F.OC1CC(c2cccc(C#Cc3ccc(OC(F)F)cc3)c2)C1>>C=CCC(F)c1cccc(C#Cc2ccc(OC(F)F)cc2)c1,,ClCCl,,,,test
US05130339,COc1cccc2c1CCC(C#N)=C2.Cl>>COc1cccc2c1CCC(CN)C2.Cl,,C1CCOC1,CCO,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20040167155A1,COc1ccc(S(=O)(=O)NC(C)c2ccccc2-c2ccc(F)cc2F)cc1>>COc1ccc(S(=O)(=O)N2c3cc(F)ccc3-c3ccccc3C2C)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080234199A1,CCCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(OCCCC(=O)OCC)cc1>>CCCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(OCCCC(=O)O)cc1,,C1CCOC1,,CCO,[Na+].[OH-],test
US05399703,CN(C(=O)C(F)(F)F)c1ccccc1Sc1ccccc1C#N>>CNc1ccccc1Sc1ccccc1C#N,,CCO,,[Na+].[OH-],,test
US20120214762A1,Nc1nccc(-n2c(C(Cl)(Cl)Cl)nc3ccc(Br)cc32)n1.OCC(O)CO>>Nc1nccc(-n2c(OCC(O)CO)nc3ccc(Br)cc32)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140142097A1,COC(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccncc3)c2)cc1>>Nc1ncc(-c2ccc(C(=O)O)cc2)cc1C(=O)Nc1ccncc1,,CO,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150336935A1,COc1cc(OC)cc(OC[C@H]2C(C)=CC[C@H]3C(C)(C)CCC[C@]23C)c1>>COc1cc(O)cc(OC[C@H]2C(C)=CC[C@H]3C(C)(C)CCC[C@]23C)c1,,CN1CCCC1=O,,,,test
US20130225524A1,COc1cc(NS(=O)(=O)C(F)(F)F)cc([N+](=O)[O-])c1.COc1ncc(-c2ccc3c(Cl)c(C(N)=O)cnc3c2)c(OC)n1>>COc1cc(Nc2c(C(N)=O)cnc3cc(-c4cnc(OC)nc4OC)ccc23)cc(NS(=O)(=O)C(F)(F)F)c1,[Pd],CC(=O)O,,[H][H],,test
US06326369B1,CCOC(=O)C1(CCCCCCCCO)Cc2c(c(OC)c(OC)c(OC)c2OC)C1>>COc1c2c(c(OC)c(OC)c1OC)CC(CCCCCCCCO)(C(=O)O)C2,,CCO,,[Na+].[OH-],,test
US05877199,CC1(C)COC(CC(CCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)Sc2cc3ccccc3[nH]2)=N1>>CC1(C)COC(CC(CCO)Sc2cc3ccccc3[nH]2)=N1,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06855711B1,C1CCNCC1.Oc1ccc(CCl)c2cccnc12>>Oc1ccc(CN2CCCCC2)c2cccnc12,,ClC(Cl)Cl,,,,test
US04226773,CC(=O)N1CCN=C1Nc1c(C)c(C)nn1C>>Cc1nn(C)c(NC2=NCCN2)c1C,,CO,,Cl,,test
US05912244,CC(C)(C)[Si](C)(C)Cl.CC1=Cc2cc(Sc3ccccc3O)ccc2OC1(C)C>>CC1=Cc2cc(Sc3ccccc3O[Si](C)(C)C(C)(C)C)ccc2OC1(C)C,,CN(C)C=O,,O,c1c[nH]cn1,test
US05187192,CN(C)C=O.Fc1ccc(Oc2cccs2)cc1>>O=Cc1ccc(Oc2ccc(F)cc2)s1,,C1CCOC1,,[Li]CCCC,,test
US04536505,CCOC(=O)CCc1cn(-c2cccnc2)c2ccccc12>>O=CCCc1cn(-c2cccnc2)c2ccccc12,,Cc1ccccc1,ClCCl,CC(C)C[Al+]CC(C)C.[H-],,test
US06028192,O=C(Cl)c1ccccc1.O=C1CCCCCN1>>O=C1CCCCCN1C(=O)c1ccccc1,,O,,CCN(C(C)C)C(C)C,,test
US20080242681A1,CC1Cc2cc(-c3cc(=O)[nH]c(=S)[nH]3)ccc2O1>>CC1Cc2cc(-c3cc(=O)[nH]cn3)ccc2O1,[Ni],O,,N,,test
US20100087427A1,CC(C)(C)OC(=O)N1C[C@@H](Cc2ccccc2)[C@H](CN(Cc2cccc(N)c2)c2ccc(Cl)cc2)C1>>Nc1cccc(CN(C[C@H]2CNC[C@@H]2Cc2ccccc2)c2ccc(Cl)cc2)c1,,C1COCCO1,Cl,,,test
US20070032478A1,Cc1ccoc1C(=O)O.Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3)c1>>Cc1ccoc1C(=O)Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3)c1,,C1CCOC1,,O=S(Cl)Cl,,test
US20150272886A1,CCCCCCCCCCCCCCC(O)CCCCCCCCCCCCCC.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCCCCCCCCCCCCCC(CCCCCCCCCCCCCC)OC(=O)Oc1ccc([N+](=O)[O-])cc1,,ClCCl,,,,test
US20040122244A1,CC(C)(C)OC(=O)c1ccc(N)cc1.COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)O)c2)=C(C)C1=O>>COC1=C(OC)C(=O)C(Cc2ccc(OC(C)=O)c(C(=O)Nc3ccc(C(=O)OC(C)(C)C)cc3)c2)=C(C)C1=O,,ClCCl,,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US20150094350A1,CC(C)C1OC(C)(C)c2cccc(N)c21.Cn1nc(C(F)F)c(C(=O)Cl)c1F>>CC(C)C1OC(C)(C)c2cccc(NC(=O)c3c(C(F)F)nn(C)c3F)c21,,ClCCl,,CCN(CC)CC,,test
US20040010147A1,CCOC(=O)C1CCNCC1.COc1cc(-c2cc(CCl)ccn2)cc(OC)c1OC>>CCOC(=O)C1CCN(Cc2ccnc(-c3cc(OC)c(OC)c(OC)c3)c2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140348748A1,CCOCOc1ccc2nc(-c3ccc(N(C)C(=O)C(C)(C)C)c(Cl)n3)sc2c1.O=C(O)C(F)(F)F>>CNc1ccc(-c2nc3ccc(O)cc3s2)nc1F,,CN(C)C=O,,,,test
US20010004669A1,CN1CCN(c2cccc3ccc(N)cc23)CC1.O=C(Cl)c1ccc(Cl)cc1>>CN1CCN(c2cccc3ccc(NC(=O)c4ccc(Cl)cc4)cc23)CC1,,CC#N,,CCN(CC)CC,,test
US05061706,CCOC(=O)C(=O)Nc1ccc(C#N)cc1.O=[N+]([O-])O>>CCOC(=O)C(=O)Nc1ccc(C#N)cc1[N+](=O)[O-],,CC(=O)O,,CC(=O)OC(C)=O,,test
US20090318405A1,Nc1ccc([N+](=O)[O-])cc1.O=C(Cl)OCCCCl>>O=C1OCCCN1c1ccc([N+](=O)[O-])cc1,CN(C)c1ccncc1,,,C1CCOC1,CC(C)(C)[O-].[K+],test
US04071680,CC1(C)OC2[C@@H](O1)[C@@H](CI)O[C@H]2n1cc(F)c(N)nc1=O>>Nc1nc(=O)n([C@@H]2O[C@H](CI)[C@@H](O)[C@H]2O)cc1F,,O,O=C(O)C(F)(F)F,,,test
US20060235030A1,CSc1nc(Cl)c2c(n1)N(c1c(F)cccc1F)C(=O)NC2.Cc1ccc(C(=O)N(C)C)cc1B1OC(C)(C)C(C)(C)O1>>CSc1nc(-c2cc(C(=O)N(C)C)ccc2C)c2c(n1)N(c1c(F)cccc1F)C(=O)NC2,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20100144707A1,COc1cc2nc(-c3ccc(-c4ccccc4)c(F)c3)nc(Nc3ccc4c(cnn4C(=O)OC(C)(C)C)c3)c2cc1O.ClCCBr>>COc1cc2nc(-c3ccc(-c4ccccc4)c(F)c3)nc(Nc3ccc4c(cnn4C(=O)OC(C)(C)C)c3)c2cc1OCCCl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090036450A1,CC(C)(C)OC(=O)NCC(=O)O.NNC(=O)c1cccc(Cl)c1>>CC(C)(C)OC(=O)NCC(=O)NNC(=O)c1cccc(Cl)c1,,ClC(Cl)Cl,,O,O=C(n1ccnc1)n1ccnc1,test
US20150126490A1,CC(O)Cc1cnc(N)c(-c2ccc(C(=O)NCc3ccccc3)c(F)c2)n1>>C[C@@H](O)Cc1cnc(N)c(-c2ccc(C(=O)NCc3ccccc3)c(F)c2)n1,,CO,,,,test
US20070010537A1,COC(=O)c1ccccc1NC(=O)Nc1cc(C(=O)N2CCCc3ccccc32)ccc1Cl>>O=C(c1ccc(Cl)c(-n2c(=O)[nH]c3ccccc3c2=O)c1)N1CCCc2ccccc21,,CCO,,Cl,[K+].[OH-],test
US20090118283A1,COC(=O)c1ccc(C(CC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)CC(NC(=O)OC(C)(C)C)c1ccc(C(=O)O)cc1,,CO,,[Li+].[OH-],,test
US20160145218A1,NCCc1ccc(Cl)cc1.O=C(O)Cn1nnc2ccccc2c1=O>>O=C(Cn1nnc2ccccc2c1=O)NCCc1ccc(Cl)cc1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US04886807,COC(OC)N(C)C.Cn1c(N)c(C#N)c(=O)n(C)c1=O>>CN(C)C=Nc1c(C#N)c(=O)n(C)c(=O)n1C,,CN(C)C=O,,,,test
US05872115,CCCCCCCNC(=O)Nc1ccccc1C(=O)NC1CCN(Cc2ccccc2)CC1>>CCCCCCCNC(=O)Nc1ccccc1C(=O)NC1CCNCC1,[Pd],CO,,[H][H],,test
US06063810,CCCC(Oc1ccccc1Br)C(=O)N(C)OC.C[Mg]Br>>CCCC(Oc1ccccc1Br)C(C)=O,,CCOCC,,C1CCOC1,Cl,test
US20100298377A1,CC(C)(C)OC(=O)N1CCCC[C@H]1[C@H](OC(=O)Nc1ccc2c(cnn2C(=O)OC(C)(C)C)c1)c1cc(F)cc(Cl)c1>>O=C(Nc1ccc2[nH]ncc2c1)O[C@H](c1cc(F)cc(Cl)c1)[C@@H]1CCCCN1,,CO,,Cl,,test
US20090181965A1,CO.COc1cc(Nc2ncc3c(n2)C(OS(C)(=O)=O)CCC3)ccc1-n1cnc(C)c1>>COc1cc(Nc2ncc3c(n2)C(OC)CCC3)ccc1-n1cnc(C)c1,,CO,O,C,C[O-].[Na+],test
US20050014804A1,CC(C)CC1CC1(CNC(=O)OC(C)(C)C)c1noc(=O)[nH]1.Cl>>CC(C)CC1CC1(CN)c1noc(=O)[nH]1.Cl,,C1COCCO1,CCOCC,,,test
US20050124676A1,Cc1oc(-c2ccccc2)cc1C(=O)Nc1ccc(CC(=O)O)cc1.NS(=O)(=O)c1ccccc1>>Cc1oc(-c2ccccc2)cc1C(=O)Nc1ccc(CC(=O)NS(=O)(=O)c2ccccc2)cc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US05254685,C1CCNC1.CN1CCc2c(F)ccc3c(=O)c(C(=O)O)cn1c23>>CN1CCc2c(N3CCCC3)ccc3c(=O)c(C(=O)O)cn1c23,,CCO,,CC#N,,test
US05198434,CCc1cc(=O)c2nc(OC)ccc2[nH]1>>CCc1cc(=O)c2c([nH]1)CCCN2,O=[Pt],CC(=O)O,,[H][H],,test
US20090062223A1,CC(C)C(=O)OCOC(=O)Nc1cc2c(=O)[nH]ncc3nn(C4OC(C(C)(C)O[SiH2]C(C)(C)C)C(OC(=O)C(NC(=O)OCc5ccccc5)C(C)C)C4(C)O)cc1c32>>CC(C)C(=O)OCOC(=O)Nc1cc2c(=O)[nH]ncc3nn(C4OC(CO)C(OC(=O)C(NC(=O)OCc5ccccc5)C(C)C)C4(C)O)cc1c32,,C1CCOC1,,,,test
US06133457,CC(C)(C)OO.OCC=CCCc1ccccc1>>OC[C@@H]1O[C@H]1CCc1ccccc1,,ClCCl,,,,test
US20130217709A1,C[N+](=O)[O-].O=Cc1cccc(F)c1>>O=[N+]([O-])CC(O)c1cccc(F)c1,,CO,O,Cl,[Na+].[OH-],test
US05739129,COc1ccc(N(C(=O)CN2C(=O)C(N)C(=O)N(c3ccccn3)c3ccccc32)C(C)C)cc1.O=C=Nc1ccccc1>>COc1ccc(N(C(=O)CN2C(=O)C(NC(=O)Nc3ccccc3)C(=O)N(c3ccccn3)c3ccccc32)C(C)C)cc1,,ClCCl,,,,test
US20150291521A1,CC(=O)CCC(C)=O.Nc1cc(Br)ccc1C(=O)O>>Cc1ccc(C)n1-c1cc(Br)ccc1C(=O)O,,Cc1ccccc1,,,,test
US20120165382A1,COC(=O)CCc1cc(C)n(C(OCc2ccc(Cl)cc2)c2cccc(Cl)c2)n1>>Cc1cc(CCC(=O)O)nn1C(OCc1ccc(Cl)cc1)c1cccc(Cl)c1,,C1CCOC1,O,[Li+].[OH-],,test
US04189594,O=C(COc1ccc(Cl)cc1)COc1ccc(CCC(=O)OCc2ccccc2)cc1>>O=C(O)CCc1ccc(OCC(=O)COc2ccc(Cl)cc2)cc1,[Pd],CC(C)=O,,CC(=O)O,[H][H],test
US20050277652A1,CN1CC(N2CCN(C(=O)Nc3cc(Oc4ccc(N)cc4)ccn3)CC2)C1.O=C=NC(=O)Cc1ccc(F)cc1>>CN1CC(N2CCN(C(=O)Nc3cc(Oc4ccc(NC(=O)NC(=O)Cc5ccc(F)cc5)cc4)ccn3)CC2)C1,,C1CCOC1,CCOC(C)=O,CCOCC,,test
US20050176761A1,CCCC(=O)Cl.CNc1ccc([N+](=O)[O-])cc1>>CCCC(=O)N(C)c1ccc([N+](=O)[O-])cc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20040121989A1,CCCCc1n[nH]c(C(F)(F)CCC)n1.COC(=O)c1ccccc1-c1ccc(CBr)cc1>>CCCCc1nc(C(F)(F)CCC)nn1Cc1ccc(-c2ccccc2C(=O)O)cc1,,CN(C)C=O,CO,[H][H],[H-].[Na+],test
US04360470,COC(=O)CC[C@@H](C)C1=CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(C)=O)C[C@H](OC(C)=O)[C@]4(C)[C@H]3CC[C@]12C>>COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(C)=O)C[C@H](OC(C)=O)[C@]4(C)[C@H]3CC[C@]12C,[Pt],CCO,,[H][H],,test
US20040132762A1,CS(=O)(=O)OS(C)(=O)=O.NCCCn1c(CCCOc2ccccc2)nc2c(N)nc3ccccc3c21>>CS(=O)(=O)NCCCn1c(CCCOc2ccccc2)nc2c(N)nc3ccccc3c21,,ClC(Cl)Cl,,,,test
US20110152273A1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1N.COC(=O)c1c(C#N)cc(Cl)nc1Nc1ccc(F)c(C)c1>>COC(=O)c1c(C#N)cc(N[C@@H]2CCCC[C@@H]2NC(=O)OC(C)(C)C)nc1Nc1ccc(F)c(C)c1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,O,test
US20100035864A1,CC1(C)CC(=O)OC1=O.Cl.O=C(Nc1ccc(N2CCCNCC2)cc1)c1nc(-c2ccccc2)oc1C(F)(F)F>>CC(C)(CC(=O)N1CCCN(c2ccc(NC(=O)c3nc(-c4ccccc4)oc3C(F)(F)F)cc2)CC1)C(=O)O.Cl,,ClCCl,,,,test
US20050288273A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCc2c(COCc4ccccc4)n[nH]c2-3)C(=O)O1>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCc2c(CO)n[nH]c2-3)C(=O)O1,[Pd],C1CCOC1,,CO,,test
US20150353552A1,CI.Clc1ncnc2[nH]cnc12>>Cn1cnc2c(Cl)ncnc21,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US06159904,BrBr.CCOC(=O)c1cc(C)c2c(c1C)C(=O)CCS2>>CCOC(=O)c1cc(C)c2c(c1C)C(=O)C(Br)CS2,,CCO,,,,test
US05578627,Cl.NC(CO)COc1noc2ccc(Cl)cc12>>Cl.NC(CO)COc1noc2ccc(Cl)cc12,,CCOC(C)=O,,C1COCCO1,,test
US05135938,CCCCCCCCCCCCc1ccccc1C(Cl)C(=O)OC.SCCc1nnn[nH]1>>CCCCCCCCCCCCc1ccccc1C(SCCc1nnn[nH]1)C(=O)OC,,ClCCl,,CCN(CC)CC,,test
US20160159815A1,COC(=O)c1ccc(O)c(Cl)n1.O=S(=O)(OCCOC(F)(F)F)C(F)(F)F>>COC(=O)c1ccc(OCCOC(F)(F)F)c(Cl)n1,,CN(C)C=O,,O,[H-].[Na+],test
US20120088750A1,CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(CC)(C(=O)OCC)CC4)nc3)cc(COC)c2s1>>CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(CC)(C(=O)O)CC4)nc3)cc(COC)c2s1,,CCO,O,[Na+].[OH-],,test
US20110218197A1,C1COCCN1.Nc1nc(-c2ccccc2C(F)(F)F)cc(Cl)c1[N+](=O)[O-]>>Nc1nc(-c2ccccc2C(F)(F)F)cc(N2CCOCC2)c1[N+](=O)[O-],,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100029606A1,CC#N.COC(=O)c1ccc2cc(OC)ccc2c1>>COc1ccc2cc(C(=O)CC#N)ccc2c1,,Cc1ccccc1,,[H-].[Na+],,test
US06740647B1,BrC(Br)(Br)Br.Cc1c(C#N)csc1CO>>Cc1c(C#N)csc1CBr,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20120190751A1,CC(=O)O.COc1ccc(C=O)c(Cl)c1OC.N=C(N)NN>>CC(=O)O.COc1ccc(C=NNC(=N)N)c(Cl)c1OC,,CO,,O=C(O)O,,test
US07432289B2,Cc1ccc(N)cc1-c1ccc(C(=O)NCC2CC2)cc1.O=C(O)c1cc(C2CC2)nc2ccccc12>>Cc1ccc(NC(=O)c2cc(C3CC3)nc3ccccc23)cc1-c1ccc(C(=O)NCC2CC2)cc1,,C1CCOC1,,,,test
US20110034484A1,CC(C)(N[C@@H]1C[C@H](c2cccc(OC(F)(F)F)c2)N(c2ccc(C(F)(F)F)cc2)C1=O)c1ccnc(C(F)(F)F)n1.O=C(O)CCCCC(=O)O>>CC(C)(N[C@@H]1C[C@H](c2cccc(OC(F)(F)F)c2)N(c2ccc(C(F)(F)F)cc2)C1=O)c1ccnc(C(F)(F)F)n1.O=C(O)CCCCC(=O)O,,CCOC(C)=O,CO,,,test
US05929074,COc1ccc(CNc2cn[nH]c(=O)c2Br)cc1OCCN1CCN(Cc2ccc(Cl)cc2)CC1.O=C(O)/C=C/C(=O)O>>COc1ccc(CNc2cn[nH]c(=O)c2Br)cc1OCCN1CCN(Cc2ccc(Cl)cc2)CC1.O=C(O)/C=C/C(=O)O,,CCOCC,,ClC(Cl)Cl,,test
US04089875,CCOC(=O)C(N=C(c1ccccc1)c1cc(Cl)ccc1O)C(=O)OCC.O=C(Cl)c1ccccc1>>CCOC(=O)C(N=C(c1ccccc1)c1cc(Cl)ccc1OC(=O)c1ccccc1)C(=O)OCC,,c1ccncc1,,,,test
US20040019059A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C(c1ccccc1)c1ccc(NC(=O)C2CC(c3cccnc3)=NO2)cc1>>NC(c1ccccc1)c1ccc(NC(=O)C2CC(c3cccnc3)=NO2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100056524A1,C1CCNC1.O=C=Nc1cccc([N+](=O)[O-])c1>>O=C(Nc1cccc([N+](=O)[O-])c1)N1CCCC1,,C1CCOC1,,,,test
US20050277659A1,CC(O)c1ccccc1Br.CCOC(=O)N1CCC(=O)CC1>>CCOC(=O)N1CCC(O)(c2ccccc2C(C)O)CC1,,C1CCOC1,,[Li]CCCC,,test
US20070161574A1,C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H](Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)CN1C(=O)NN)C(=O)OCC.O=Cc1ccccc1>>C=C[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H](Oc2cc(-c3ccccc3)nc3cc(OC)ccc23)CN1C(=O)NNCc1ccccc1)C(=O)OCC,,C1CCOC1,CO,Cl,,test
US20140221333A1,CC1CCC(n2nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)ccn4)cc3)c3c(N)ncnc32)CN1C(=O)OC(C)(C)C>>C[C@@H]1CC[C@H](n2nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)ccn4)cc3)c3c(N)ncnc32)CN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080311635A1,CC(C)C[C@H](CNC(=O)OC(C)C)CC(=O)O>>CC(C)C[C@H](CN)CC(=O)O,,Cc1ccccc1,O,Cl,[Na+].[OH-],test
US20150166512A1,CCc1ccc(Cl)cc1N.COC1CCC(OC)O1>>CCc1ccc(Cl)cc1-n1cccc1,,CC(=O)O,,,,test
US04423068,CC1(C)C(=O)N(Br)C(=O)N1Br.O.O=C1C=C(C2=CCCCCC2)CCCC1>>O=C1CC2C1CC(O)C2Br,,O,,CC(C)=O,,test
US20050038043A1,CCCc1c(Cn2ccnc2-c2cccc(F)n2)ncnc1N=[N+]=[N-]>>CCCc1c(N)ncnc1Cn1ccnc1-c1cccc(F)n1,[Pd],CO,,,,test
US20130331374A1,CC(C)(C)OC(=O)N1CC[C@H](O)[C@@H](F)C1.O=[N+]([O-])c1ccc(F)c(Cl)c1>>CC(C)(C)OC(=O)N1CC[C@H](Oc2ccc([N+](=O)[O-])cc2Cl)[C@@H](F)C1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20150307493A1,BrBr.CS(=O)(=O)c1ccc(O)c([N+](=O)[O-])c1>>CS(=O)(=O)c1cc(Br)c(O)c([N+](=O)[O-])c1,,CC(=O)O,O,,,test
US20130331378A1,COC(=O)c1cccc(C=O)n1.COc1cc([Si](C)(C)C)n2nc(-c3ccccc3)c(Br)c2c1>>COC(=O)c1cccc(C(O)c2c(-c3ccccc3)nn3c([Si](C)(C)C)cc(OC)cc23)n1,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US20100113444A1,CCOC(=O)CNC(=O)c1c(O)n(C2CCCCC2)c(=O)[nH]c1=O.Fc1cccc(CBr)c1F>>O=C(O)CNC(=O)c1c(O)n(C2CCCCC2)c(=O)n(Cc2cccc(F)c2F)c1=O,,CC(=O)N(C)C,,Cl,O=C([O-])[O-].[K+].[K+],test
US20050245572A1,N#Cc1cc(CO)c2ccccc2c1.[I-]>>N#Cc1cc(CI)c2ccccc2c1,,CC#N,,CCOC(C)=O,,test
US20120108586A1,O=S(=O)(OCC(F)F)C(F)(F)F.Oc1cnccc1-c1nc2cc(C(F)(F)F)cnc2o1>>FC(F)COc1cnccc1-c1nc2cc(C(F)(F)F)cnc2o1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130102586A1,CC1(C)OB(c2cnc3[nH]ccc3c2)OC1(C)C.FC1(F)CCN(c2cncc(Cl)n2)C1>>FC1(F)CCN(c2cncc(-c3cnc4[nH]ccc4c3)n2)C1,,C1COCCO1,ClC(Cl)Cl,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080262041A1,C=O.C[C@@H](c1cc(Cl)cc2ccccc12)N1CCC(C2(c3ccc(F)cc3)CCNCC2)C1=O>>C[C@@H](c1cc(Cl)cc2ccccc12)N1CCC(C2(c3ccc(F)cc3)CCN(C)CC2)C1=O,,CC#N,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US06303593B1,O=C1OC[C@H](Cc2ccccc2)N1C(=O)[C@@H]1CN(Cc2ccccc2)C[C@H]1c1ccsc1>>OC[C@@H]1CN(Cc2ccccc2)C[C@H]1c1ccsc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100317643A1,CC(C)OC(=O)Cl.Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1>>CC(C)OC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1,,c1ccncc1,,,,test
US20150031708A1,COc1ncc(-c2nc(NC(=O)C3(c4ccc5c(c4)OCCO5)CC3)ccc2C)cc1C>>Cc1ccc(NC(=O)C2(c3ccc4c(c3)OCCO4)CC2)nc1-c1c[nH]c(=O)c(C)c1,,CC#N,ClCCl,C[Si](C)(C)I,,test
US20100063068A1,CS(=O)(=O)N(c1cnccc1OCc1ccccc1)S(C)(=O)=O>>CS(=O)(=O)Nc1cnccc1OCc1ccccc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100249110A1,CCOC(=O)C1CN(c2ccccc2)c2nc(SC)nc(NN)c2C1=O>>CSc1nc2c3c(n[nH]c3n1)C(C(=O)O)CN2c1ccccc1,,CCO,,[Na+].[OH-],,test
US20090275567A1,Cc1ncc(-c2nc(NC3CCN(C(=O)OCc4ccccc4)CC3)ncc2F)n1C(C)C>>Cc1ncc(-c2nc(NC3CCNCC3)ncc2F)n1C(C)C,[Pd],CC#N,CCO,,,test
US20160016948A1,CC(C)(C)[Si](C)(C)Cl.CC(C)(CO)Nc1cc(Br)ncc1[N+](=O)[O-]>>CC(C)(CO[Si](C)(C)C(C)(C)C)Nc1cc(Br)ncc1[N+](=O)[O-],CN(C)c1ccncc1,C1CCOC1,O,c1c[nH]cn1,,test
US06162944,CCO.CCOC1(O[Si](C)(C)C)CC1.COc1c(N)ccc(F)c1F>>CCON(c1ccc(F)c(F)c1OC)C1CC1,,CCO,,CC(=O)O,,test
US20080275103A1,CC(C)[C@@H](C=O)NC(=O)OC(C)(C)C.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CCC(=O)N1Br>>COC(=O)/C(Br)=C/C(NC(=O)OC(C)(C)C)C(C)C,,ClCCl,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20060128712A1,CS(=O)(=O)c1ccc(OCC2CC2)c(C(=O)O)c1.c1ccc2c(N3CCNCC3)nsc2c1>>CS(=O)(=O)c1ccc(OCC2CC2)c(C(=O)N2CCN(c3nsc4ccccc34)CC2)c1,,CC#N,,CCOC(C)=O,Cl,test
US20150191434A1,CC(C)(C)OC(=O)C1CC=C(c2c[nH]c3cccc(F)c23)CC1.O=C(Cl)c1c(Cl)cccc1C(F)(F)F>>CC(C)(C)OC(=O)C1CC=C(c2cn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccc(F)c23)CC1,,CCOC(C)=O,,CN(C)C=O,[H-].[Na+],test
US20110206783A1,C=C(C)c1cc(C(=O)OC)cc(-c2ccc(C)cn2)n1>>COC(=O)c1cc(-c2ccc(C)cn2)nc(C(C)C)c1,[Pd],CCO,,,,test
US20090238761A1,CCOC(=O)c1cc2cccc(OC)c2[nH]1.N#CCBr>>CCOC(=O)c1cc2cccc(OC)c2n1CC#N,,CN(C)C=O,,[H-].[Na+],,test
US05326868,CCOC(=O)c1[nH]c2ccccc2c1N.O=C(Cl)c1ccccc1>>CCOC(=O)c1[nH]c2ccccc2c1NC(=O)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20050009845A1,C#CC(C)N1C(=O)c2ccccc2C1=O.Clc1ncnc2cc(Br)sc12>>CC(C#Cc1cc2ncnc(Cl)c2s1)N1C(=O)c2ccccc2C1=O,[Cu]I,C1CCOC1,,CCN(CC)CC,,test
US06300352B1,CSc1cccc(Br)c1.O=S([O-])OO>>CS(=O)(=O)c1cccc(Br)c1,,O,,CO,,test
US08524715B2,CC(C)(C)OC(=O)NC1CCNC1.O=S(=O)(Cl)c1ccccc1>>CC(C)(C)OC(=O)NC1CCN(S(=O)(=O)c2ccccc2)C1,,C1CCOC1,CCOCC,CCN(CC)CC,O,test
US20160272617A1,COC(=O)c1c(F)cc(-c2ccc(C[C@H](NC(=O)[C@@H]3CC[C@@H](CNC(=O)OC(C)(C)C)CC3)C(=O)Nc3ccc(-c4nnn[nH]4)cc3)cc2)cc1F>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2ccc(-c3cc(F)c(C(=O)O)c(F)c3)cc2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)CC1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20090156603A1,COc1cccc(S)c1.N#Cc1ncc(Br)cc1[N+](=O)[O-]>>COc1cccc(Sc2cc(Br)cnc2C#N)c1,,O,,CN(C)C=O,[H-].[Na+],test
US20030158245A1,CCCSc1sc(C(N)=O)c2c1-c1c(cnn1C)CC2.Cl>>CCCSc1sc(C(N)=O)c2c1-c1c(cnn1C)CC2.Cl,,C1CCOC1,,CCOC(C)=O,,test
US04595700,CC(C)C=O.CCOP(=O)(OCC)C(CC(C)C)C(=O)OC>>COC(=O)C(=CC(C)C)CC(C)C,,C1CCOC1,CCOCC,O,[H-].[Na+],test
US20120214767A1,CO.O=C(O)c1noc(-c2ccccc2)c1C(F)(F)F>>COC(=O)c1noc(-c2ccccc2)c1C(F)(F)F,,CO,,ClCCl,,test
US20050075499A1,CCOC(=O)CN1CCc2ccccc2C1>>O=C(O)CN1CCc2ccccc2C1,,CO,,Cl,[Na+].[OH-],test
US20150094328A1,Cc1ccnc(CCl)c1.O=C(N[C@H]1CCCC[C@@H]1O)c1c[nH]c2c(Cl)ccnc12>>Cc1ccnc(Cn2cc(C(=O)N[C@H]3CCCC[C@@H]3O)c3nccc(Cl)c32)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20040053991A1,CCOC(=O)C=C(C)c1ccc(-c2ccc(Cl)cc2)cc1>>CC(C=CO)c1ccc(-c2ccc(Cl)cc2)cc1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090181928A1,CS(=O)(=O)N1Cc2ccccc2C[C@H]1/C=C/c1ccc(N2CC(=O)NS2(=O)=O)c(OCc2ccccc2)c1>>CS(=O)(=O)N1Cc2ccccc2C[C@H]1CCc1ccc(N2CC(=O)NS2(=O)=O)c(O)c1,[Pd],CCO,,,,test
US20100105906A1,O=C(O)c1cccnc1Oc1cc(Cl)ccc1Cl.c1ccc2c(c1)NCCO2>>O=C(c1cccnc1Oc1cc(Cl)ccc1Cl)N1CCOc2ccccc21,,ClCCl,,CCN(CC)CC,C[n+]1ccccc1Cl.[I-],test
US20110166118A1,C=CCOC(=O)C1=C2[C@@H](OC)CCC[C@@H]2[C@@H]2[C@@H]([C@H](O[Si](C)(C)C)C(F)(F)F)C(=O)N12>>C=CCOC(=O)C1=C2[C@@H](OC)CCC[C@@H]2[C@@H]2[C@@H]([C@H](O)C(F)(F)F)C(=O)N12,,C1CCOC1,,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US06479512B1,CC(C)(C)OC(=O)Nc1ccccn1.CN(C)C=O>>CC(C)(C)OC(=O)Nc1ncccc1C=O,,CCOCC,,[Li]C(C)(C)C,,test
US20110021487A1,CC(C)(C)[Si](C)(C)O[C@@H]1COC[C@H]1Oc1ccc(C=O)cc1.N#CCC#N>>CC(C)(C)[Si](C)(C)O[C@@H]1COC[C@H]1Oc1ccc(C=C(C#N)C#N)cc1,,CCO,,CN1CCOCC1,,test
US20110028493A1,CCOC(=O)c1cnn(CC(=O)NN)c1.O=C(Cl)c1cccc(C(F)(F)F)c1>>CCOC(=O)c1cnn(CC(=O)NNC(=O)c2cccc(C(F)(F)F)c2)c1,,ClCCl,,CCN(CC)CC,,test
US20020123488A1,CSc1nnc(C#N)c(N2CCc3ccccc3CC2)n1.O=C(OO)c1cccc(Cl)c1>>N#Cc1nnc(O)nc1N1CCc2ccccc2CC1,,ClCCl,,,,test
US20150210720A1,CCOC(=O)C(=O)CBr.O=C1CCCNC(=O)C1>>CCOC(=O)C1(O)COC2=C1C(=O)NCCC2,,CO,O,[K+].[OH-],,test
US05534515,BrBr.COc1ccc(Cn2c(C)cc3cnnc(OCc4ccccc4)c32)cc1>>COc1ccc(Cn2c(C)c(Br)c3cnnc(OCc4ccccc4)c32)cc1,,ClCCl,,,,test
US20110053974A1,Cc1ccccc1CBr.O=Cc1ccc(O)cc1>>Cc1ccccc1COc1ccc(C=O)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20150087663A1,C[C@H](N)c1nc2cccc(-c3cnn(C)c3)c2c(=O)n1C1CC1.Cc1nnc(-c2c(N)ncnc2Cl)o1>>Cc1nnc(-c2c(N)ncnc2N[C@@H](C)c2nc3cccc(-c4cnn(C)c4)c3c(=O)n2C2CC2)o1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US04547524,CC(=O)Cl.CC(C)=NNC(=O)c1ccc(Cl)cc1>>CC(=O)N(N=C(C)C)C(=O)c1ccc(Cl)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20150119456A1,CC(C)(C)[Si](C)(C)Cl.COC(=O)c1c(C)cccc1O>>COC(=O)c1c(C)cccc1O[Si](C)(C)C(C)(C)C,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100292212A1,CCOC(=O)C1(CC#N)CCN(S(=O)(=O)c2ccccc2Cl)CC1>>CCOC(=O)C1(CCN)CCN(S(=O)(=O)c2ccccc2Cl)CC1,O=[Pt]=O,CC(=O)O,CO,,,test
US20090318429A1,CCOC(=O)c1csc(-c2cc(Cl)c(OC)c(Cl)c2)n1>>O=C(O)c1csc(-c2cc(Cl)c(O)c(Cl)c2)n1,,ClCCl,,BrB(Br)Br,,test
US20030028029A1,CC(C)(C(=O)O)c1ccc(C(=O)CCCCl)cc1>>CC(C)(C(=O)O)c1ccc(C(O)CCCCl)cc1,,CO,,Cl,[BH4-].[Na+],test
US20130096113A1,CCOC(OCC)OCC.COc1cc(NCc2ccc3nc(SC)sc3c2)c(N)cc1Br>>COc1cc2c(cc1Br)ncn2Cc1ccc2nc(SC)sc2c1,,O=CO,,,,test
US20090036450A1,CC(=NO)NC(=O)c1noc(C)c1C(=O)OC(C)(C)C>>Cc1noc(-c2noc(C)c2C(=O)OC(C)(C)C)n1,,CCO,,O,CC(=O)[O-].[Na+],test
US20160143895A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(C(O)CO)cc12.CS(=O)(=O)Cl>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(C(O)COS(C)(=O)=O)cc12,,O,c1ccncc1,,,test
US05859012,CC(C)(C)OC(=O)N[C@H](C=O)Cc1ccccc1.Nc1ccccc1>>CC(C)(C)OC(=O)N[C@H](CNc1ccccc1)Cc1ccccc1,,CC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20140080813A1,Nc1cccc(F)c1.O=C(Cl)C=C1CCC1>>O=C(C=C1CCC1)Nc1cccc(F)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05789394,CCOP(=O)(OCC)[C@@H]1OC[C@@H](CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)S1>>CCOP(=O)(OCC)[C@@H]1OC[C@@H](CO)S1,,C1CCOC1,,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20130237535A1,COCC1(N2CC3(CCN(C(=O)OC(C)(C)C)CC3)OCC2=O)CC1.Cl>>COCC1(N2CC3(CCNCC3)OCC2=O)CC1.Cl,,ClCCl,,C1COCCO1,,test
US20130237535A1,CC(C)(C)[Si](C)(C)OCC1(N)CC1.O=S(=O)(c1ccc(Br)cc1)N1CCC2(CC1)CO2>>CC(C)(C)[Si](C)(C)OCC1(NCC2(O)CCN(S(=O)(=O)c3ccc(Br)cc3)CC2)CC1,,CCO,,,,test
US04694004,CC(C)(C)N=C=O.NN1CC=CCC1>>CC(C)(C)NC(=O)NN1CC=CCC1,,ClCCl,,CCN(CC)CC,Cl,test
US20070078165A1,Cc1cc([N+](=O)[O-])c(NC2CCN(C(=O)OC(C)(C)C)CC2)cc1F>>Cc1cc(N)c(NC2CCN(C(=O)OC(C)(C)C)CC2)cc1F,[Pd],CCO,,,,test
US20100125062A1,CC(=O)Cl.O=C(c1ccc(Oc2ncncc2C2=CCNCC2)cc1)c1nc2ccccc2[nH]1>>CC(=O)N1CC=C(c2cncnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)CC1,,ClCCl,O,CCN(CC)CC,,test
US20020137766A1,ClCC1CO1.N#Cc1ccc(O)cc1>>N#Cc1ccc(OCC2CO2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05334371,COC(=O)c1cc(-c2cc(C(=O)OC)nc(C(=O)OC)c2)cc(C(=O)OC)n1>>OCc1cc(-c2cc(CO)nc(CO)c2)cc(CO)n1,,C1COCCO1,O,Cl,[BH4-].[Na+],test
US20120184587A1,CC(=O)OC(C)=O.Oc1ccccc1OC(F)(F)F>>CC(=O)Oc1ccccc1OC(F)(F)F,,ClC(Cl)Cl,,CCN(CC)CC,O=C([O-])[O-].[K+].[K+],test
US20070265309A1,C[Si](C)(C)CCOC(=O)Oc1ccc([N+](=O)[O-])cc1.O=C1CCNCC1>>C[Si](C)(C)CCOC(=O)N1CCC(=O)CC1,CN(C)c1ccncc1,CC#N,,CCN(CC)CC,Cl,test
US20050239780A1,O=S(Cl)Cl.O=[N+]([O-])c1cc(S(=O)(=O)[O-])ccc1Cl>>O=[N+]([O-])c1cc(S(=O)(=O)Cl)ccc1Cl,,ClCCCl,,CN(C)C=O,,test
US20150210720A1,C=O.COc1nc(N2CC[C@@H]3CNC[C@@H]32)ccc1NC(=O)c1coc2c1C(=O)NC(C)(C)C2>>COc1nc(N2CC[C@@H]3CN(C)C[C@@H]32)ccc1NC(=O)c1coc2c1C(=O)NC(C)(C)C2,CC(=O)O,CCOC(C)=O,CO,[Na],,test
US20080300242A1,COCCN1CCNCC1.COc1cc(F)ccc1[N+](=O)[O-]>>COCCN1CCN(c2ccc([N+](=O)[O-])c(OC)c2)CC1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100004284A1,CC(C)(C)OC(=O)N1CCC[C@H](c2nc(Br)no2)C1.Oc1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@H](c2nc(Oc3ccccc3)no2)C1,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04221915,O=CC(Cl)(Cl)Cl.c1ccsc1>>OC(c1cccs1)C(Cl)(Cl)Cl,,CCCCCCC,,,,test
US20060094843A1,CCCC1(C(=O)OCC)CCCC1O.Cc1ccc(C(=O)Cl)cc1>>CCCC1(C(=O)OCC)CCCC1OC(=O)c1ccc(C)cc1,,c1ccncc1,,ClCCl,,test
US20140005418A1,COC(CNC(=O)OC(C)(C)C)c1ccc(Cl)cc1>>COC(CN)c1ccc(Cl)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150225405A1,OCc1nn(C(F)F)cc1-n1c2ccc(F)cc2c2c1cnn2C1CCCCO1>>OCc1nn(C(F)F)cc1-n1c2ccc(F)cc2c2[nH]ncc21,,C1COCCO1,,Cl,,test
US03966945,CC(O)c1ccccn1.CI>>COC(C)c1ccccn1,,CS(C)=O,,[H-].[Na+],,test
US20120128630A1,Brc1nnnn1Cc1ccccc1.O=Cc1ccc(O)cc1>>O=Cc1ccc(Oc2nnnn2Cc2ccccc2)cc1,,CN(C)C=O,,[K],,test
US04620865,CCOC(=O)c1cnn(-c2ccccc2)c1Cl.CN>>CNC(=O)c1cnn(-c2ccccc2)c1Cl,,CN(C)C=O,,,,test
US04010267,ClCc1ccc2c(c1)OC(c1ccccc1)O2.c1cnc(N2CCNCC2)nc1>>Cl.c1cnc(N2CCNCC2)nc1,,Cc1ccccc1C,,,,test
US20110275638A1,CC(C)CCNC(=O)C(C)(C)NC(=O)OC(C)(C)C>>CC(C)CCNC(=O)C(C)(C)N,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160075711A1,CCCC[Sn](CCCC)(CCCC)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.COc1cc(C=O)c(Br)cn1>>COc1cc(C=O)c(-c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)cn1,,CC#N,O,,,test
US05047554,CS(=O)(=O)c1ccc(C(=O)Cl)s1.NC(=O)N1C(=O)Cc2cc(Cl)ccc21>>CS(=O)(=O)c1ccc(C(=O)C2C(=O)N(C(N)=O)c3ccc(Cl)cc32)s1,CN(C)c1ccncc1,,,,,test
US20100093728A1,Cc1ccc(O)cn1.OCCBr>>Cc1ccc(OCCO)cn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060160794A1,C1CNCCN1.CN(Cc1ccccc1Cl)C(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1Cl>>CN(Cc1ccccc1Cl)C(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1N1CCNCC1,,C1CCOC1,CCOCC,,,test
US20100113512A1,CCOC(=O)c1ccc(-c2ccc(C=O)o2)cc1.NCCc1cccc(F)c1>>CCOC(=O)c1ccc(-c2ccc(CNCCc3cccc(F)c3)o2)cc1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150018335A1,C[C@H]1CN(Cc2ccc(N3CCOCC3)cc2C(F)(F)F)CCN1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OC(C(F)(F)F)C(F)(F)F>>C[C@H]1CN(Cc2ccc(N3CCOCC3)cc2C(F)(F)F)CCN1C(=O)OC(C(F)(F)F)C(F)(F)F,CN(C)c1ccncc1,ClCCl,O,CCN(C(C)C)C(C)C,,test
US20040138255A1,COC(=O)c1ccc(OCCOc2ccc(S(=O)(=O)C(F)(F)F)cc2[N+](=O)[O-])cc1>>O=C(O)c1ccc(OCCOc2ccc(S(=O)(=O)C(F)(F)F)cc2[N+](=O)[O-])cc1,,C1CCOC1,CCO,Cl,,test
US20020016368A1,COc1cccc(CN)c1.CS(=O)(=O)Cl>>COc1cccc(CNS(C)(=O)=O)c1,,C1CCOC1,,CCN(CC)CC,,test
US05866583,NCCc1ccccc1.O=C(O)c1ccc(Cl)nc1>>O=C(NCCc1ccccc1)c1ccc(Cl)nc1,,C1CCOC1,CN(C)C=O,O=C(n1ccnc1)n1ccnc1,,test
US20080188528A1,COC(=O)c1ccc[nH]c1=O.ClCc1cccc2ccccc12>>COC(=O)c1cccn(Cc2cccc3ccccc23)c1=O,,CN(C)C=O,,Cl,[H-].[Na+],test
US20090186898A1,C#CCNC(=O)OC(C)(C)C.CC(=O)C(F)(F)F>>CC(C)(C)OC(=O)NCC#CC(C)(O)C(F)(F)F,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US06242450B1,Brc1cncc2ccccc12.CC(C)(C)OC(=O)N1CCC(=O)CC1>>CC(C)(C)OC(=O)N1CCC(O)(c2cncc3ccccc23)CC1,,C1CCOC1,,[Li]C(C)CC,,test
US20150018342A1,CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1.O=C1CCC(=O)N1Br>>CC[C@@H](NC(=O)c1c(Br)c(C(=O)N2CCC[C@@H]2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1,,ClC(Cl)Cl,,ClCCl,,test
US20140073622A1,C1CCOC1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)C(F)(F)F.O=C1CCNCC1OCc1ccccc1>>COC1(OC)CCN(C(=O)OC(C)(C)C)CC1OCc1ccccc1,,O,,[Na+].[OH-],,test
US20100130506A1,Nc1nc(N)c(C(=O)/N=C2\NCC3(CC4CCC(C3)N4)N2)nc1Cl.O=C(O)c1cccc2[nH]ccc12>>Nc1nc(N)c(C(=O)/N=C2\NCC3(CC4CCC(C3)N4C(=O)c3cccc4[nH]ccc34)N2)nc1Cl,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040204427A1,CC(C)(C)[Si](C)(C)O[C@H]1CC[C@@H](O)C1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](C)(C)O[C@H]1CC[C@H](N=[N+]=[N-])C1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05068340,CCCCCCCCCCCCCCCCCNC(=O)OCC(COP(=O)([O-])OCCBr)Oc1ccon1.c1cscn1>>CCCCCCCCCCCCCCCCCNC(=O)OCC(COP(=O)([O-])OCCc1[nH+]ccs1)Oc1ccon1,,Cc1ccccc1,,,,test
US20090036535A1,C[C@@H](O)C(=O)OC(C)(C)C.O=S(=O)(c1ccccc1)c1ccc(-c2cc(F)ccc2O)cc1F>>C[C@H](Oc1ccc(F)cc1-c1ccc(S(=O)(=O)c2ccccc2)c(F)c1)C(=O)OC(C)(C)C,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080085890A1,N.O=c1cc(CO)occ1-c1ccoc1>>OCc1cc(O)c(-c2ccoc2)cn1,,CO,,,,test
US20060235231A1,COC(=O)C=CC=CCBr.Sc1ccc2ccccc2c1>>COC(=O)C=CC=CCSc1ccc2ccccc2c1,,CCOCC,,CCN(CC)CC,,test
US20070037807A1,CCOC(=O)c1csc(CNC(=O)OCc2ccccc2)n1>>CCOC(=O)c1csc(CN)n1,,Br,CC(=O)O,,,test
US20100216788A1,Cn1c(Cl)cc2ncnc(Cl)c21.Nc1ccc(OCc2ccccn2)c(Cl)c1>>Cn1c(Cl)cc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c21,,CC(C)O,,,,test
US20120238545A1,CS(=O)(=O)Cl.O=C(c1nn(C2CCNCC2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1>>CS(=O)(=O)N1CCC(n2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)CC1,,C1CCOC1,,CCN(CC)CC,O,test
US20160068496A1,Nc1cccc(Br)c1F.O=S(=O)(Cl)CCCF>>O=S(=O)(CCCF)Nc1cccc(Br)c1F,CN(C)c1ccncc1,ClCCl,,O,c1ccncc1,test
US20120315217A1,COc1ccc(C=O)cc1CCl.Cc1cccc(C)c1O>>COc1ccc(C=O)cc1COc1c(C)cccc1C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100240638A1,O=C(N[C@@H](CCCCCCCNC(=O)C(O)C(CC1CCC1)NC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3cccc(F)c3C2)CN1)C(=O)O)OC1CCCC1>>O=C(N[C@H]1CCCCCCCNC(=O)C(O)C(CC2CCC2)NC(=O)[C@@H]2C[C@@H](OC(=O)N3Cc4cccc(F)c4C3)CN2C1=O)OC1CCCC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140135332A1,CS(=O)(=O)Cl.NC(=O)c1c(F)ccc(OC(CO)c2nc(-c3ccc(C(F)(F)F)cc3)c(Cl)o2)c1F>>CS(=O)(=O)OCC(Oc1ccc(F)c(C(N)=O)c1F)c1nc(-c2ccc(C(F)(F)F)cc2)c(Cl)o1,,ClCCl,,CCN(CC)CC,O,test
US20070244159A1,ClCc1cc(Cl)c2c(c1)OCO2.[C-]#N>>N#CCc1cc(Cl)c2c(c1)OCO2,,CS(C)=O,,O,,test
US20040058936A1,CC(C)(C)OC(=O)N1CCN(c2cccc3cnccc23)CC1.CCO>>CCN1CCc2c(cccc2N2CCN(C(=O)OC(C)(C)C)CC2)C1,[Pt],,,,,test
US20060287363A1,CN1CCC(N(C)c2cccc(N)n2)CC1.O=C(Cl)c1c(F)cc(F)cc1F>>CN1CCC(N(C)c2cccc(NC(=O)c3c(F)cc(F)cc3F)n2)CC1.Cl,,C1COCCO1,,,,test
US20090042726A1,C1CCOC1.CI.Cn1nc(Br)c(Br)n1.Cn1nnc(Br)c1Br>>Cc1c(Br)nnn1C.Cc1nn(C)nc1Br,,C1CCOC1,,[Li]CCCC,,test
US20030203898A1,CCOC(=O)C(=O)Nc1cc(C)c(Cc2ccc(OC)c(C(C)C)c2)c(C)c1>>Cc1cc(NC(=O)C(=O)O)cc(C)c1Cc1ccc(O)c(C(C)C)c1,,ClCCl,,BrB(Br)Br,,test
US20150087672A1,Cn1c(C2CC2)nc2ccc(Br)cc21.O=c1[nH]ccc2oc(-c3ccc(Cl)cc3)cc12>>Cn1c(C2CC2)nc2ccc(-n3ccc4oc(-c5ccc(Cl)cc5)cc4c3=O)cc21,[Cu]I,CS(C)=O,,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US20090029903A1,CCCCCCN(Cc1ccc(C#Cc2ccc(CCCC)cc2)cc1)C(=O)c1ccc(O)c(C(=O)O)c1.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>CCCCCCN(Cc1ccc(C#Cc2ccc(CCCC)cc2)cc1)C(=O)c1ccc(O)c(C(=O)O)c1.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO,,CO,O,,,test
US20150191461A1,CS(=O)(=O)Cl.Cc1cc(Nc2nccc(C(F)F)n2)cc(-c2cnn(CCN)c2)c1>>Cc1cc(Nc2nccc(C(F)F)n2)cc(-c2cnn(CCNS(C)(=O)=O)c2)c1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20160229853A1,C[Si](C)(C)C#N.C[Si](C)(C)CNCc1ccccc1.O=C1COC1>>C[Si](C)(C)CN(Cc1ccccc1)C1(C#N)COC1,,CCOCC,,CC(=O)O,,test
US20150183801A1,O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(N2CC[C@@H](O)C2)c(Br)c1.OB(O)c1cncnc1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(N2CC[C@@H](O)C2)c(-c2cncnc2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20130143862A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N#Cc1ccc(NCC2(c3ncccc3F)CCC2)nn1>>CC(C)(C)OC(=O)N(CC1(c2ncccc2F)CCC1)c1ccc(C#N)nn1,CN(C)c1ccncc1,C1CCOC1,,,,test
US04590073,CCOC(=O)C=O.NC(=O)OCc1ccccc1>>CCOC(=O)C(O)NC(=O)OCc1ccccc1,,Cc1ccccc1,,O,,test
US20150158826A1,COc1cnc2ccc(C(O)c3cc(NC(=O)C(C)(C)C)ccc3F)cc2n1>>COc1cnc2ccc(C(=O)c3cc(NC(=O)C(C)(C)C)ccc3F)cc2n1,O=[Mn]=O,ClCCl,,,,test
US05403934,Cc1cc(=O)c(-c2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)c(C)[nH]1.O=C1CCC(=O)N1Cl>>Cc1[nH]c(C)c(-c2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)c(=O)c1Cl,,ClC(Cl)Cl,,,,test
US20120115811A1,Cc1cc(-c2cc(C(=O)OC(C)(C)C)cc([N+](=O)[O-])c2)ccn1>>Cc1cc(-c2cc(N)cc(C(=O)OC(C)(C)C)c2)ccn1,[Pd],CO,,[H][H],,test
US20040058919A1,COC(=O)[C@H]1CN(CCSc2cccs2)CC[C@H]1CCC(=O)c1ccnc2ccc(OC)cc12.NO>>COC(=O)[C@H]1CN(CCSc2cccs2)CC[C@H]1CCC(=NO)c1ccnc2ccc(OC)cc12,,O,c1ccncc1,Cl,,test
US05059340,CCOC(=O)CC(=O)OCC.CC[C@H](C)CBr>>CCOC(=O)C(C[C@@H](C)CC)C(=O)OCC,,CCO,,[Na],C[O-].[Na+],test
US06001839,COc1cc(-c2cn(C3CCCC3)c3ncnc(N)c23)ccc1NC(=O)c1ccccc1>>Nc1ncnc2c1c(-c1ccc(NC(=O)c3ccccc3)c(O)c1)cn2C1CCCC1,,ClCCl,,BrB(Br)Br,,test
US04699905,CC(C)(C)OC(=O)CN1C(=O)[C@@H](N)CSC[C@H]1c1cccs1.CCOC(=O)C(Br)CCc1ccccc1>>CCOC(=O)C(CCc1ccccc1)N[C@H]1CSC[C@@H](c2cccs2)N(CC(=O)OC(C)(C)C)C1=O,,CCOC(C)=O,ClCCl,,,test
US20070037816A1,O=C1CCC(=O)N1Cl.ON=Cc1cccc(Cl)c1>>ON=C(Cl)c1cccc(Cl)c1,,CCOCC,,CN(C)C=O,,test
US20150018422A1,COc1ccc(COc2ccc(-c3cc(OC)ccc3F)c(C(O)C(C)C)c2)cc1>>COc1ccc(COc2ccc(-c3cc(OC)ccc3F)c(C(=O)C(C)C)c2)cc1,,CS(C)=O,,CCN(CC)CC,Cl,test
US20110319378A1,C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)CN2CCN(C(=O)OC(C)(C)C)CC2)C1=O>>C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)CN2CCNCC2)C1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US05650399,Cc1cc(Cl)c(C)c2c1C(=O)c1ccccc1C2=O.OCCN1CCNCC1>>CC1=CCC(C)(C2CNCCN2CCO)C2=C1C(=O)c1ccccc1C2=O,,O,,,,test
US20040067955A1,COCC(C)OS(C)(=O)=O.Nc1nc(-c2ccccc2)c(-c2ccc(=O)[nH]n2)cc1Cl>>COCC(C)n1nc(-c2cc(Cl)c(N)nc2-c2ccccc2)ccc1=O,,CN(C)C=O,,O,[H-].[Na+],test
US20130303788A1,BrB(Br)Br.C=CCc1cc(-c2cc(CCC)ccc2OC)ccc1O.CCCCCC.CCOC(C)=O>>C=CCc1cc(-c2cc(CCC)ccc2O)ccc1O.C=CCc1ccc(OC)c(Br)c1,,CCCCCC,CCOC(C)=O,,,test
US20160060237A1,CCOC(=O)CC(C)c1ccc(N(CC(C)C)CC(C)C)c(N)c1.Cc1ccc(N=C=O)cc1>>Cc1ccc(NC(=O)Nc2cc(C(C)CC(=O)O)ccc2N(CC(C)C)CC(C)C)cc1,,C1CCOC1,O,CO,[Na+].[OH-],test
US20140051679A1,Nc1ccc2[nH]nc(-c3ccc(N4CCOCC4)cc3)c2c1.O=C(O)C(F)(F)F.O=C=Nc1ccccc1Cl>>O=C(Nc1ccc2[nH]nc(-c3ccc(N4CCOCC4)cc3)c2c1)Nc1ccccc1Cl.O=C(O)C(F)(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20050148777A1,CCI.CCOC(=O)C1=Cc2cc(O)cc(Cl)c2OC1C(F)(F)F>>CCOC(=O)C1=Cc2cc(OCC)cc(Cl)c2OC1C(F)(F)F,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150038643A1,C=CCCCCO.CC(C)(Br)C(=O)Br>>C=CCCCCOC(=O)C(C)(C)Br,,C1CCOC1,,CCN(CC)CC,,test
US20020058837A1,CCC(O)(c1ccc(OC)cc1)c1ccc(OC)cc1>>CC=C(c1ccc(OC)cc1)c1ccc(OC)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20160016951A1,Brc1ccc2cnccc2c1.O=S(=O)(Cl)Cl>>Clc1cncc2ccc(Br)cc12,,CCOC(C)=O,,,,test
US20160264552A1,C=CC(=O)Nc1ccc(CNC(=O)OC(C)(C)C)cc1>>C=CC(=O)Nc1ccc(CN)cc1,,CO,,CCOC(C)=O,Cl,test
US20050182072A1,CCOC(=O)CC(=O)c1ccnc(Cl)c1.CSC(=N)N>>CSc1nc(-c2ccnc(Cl)c2)cc(=O)[nH]1,,CCO,O,O=S(=O)(O)O,,test
US20130116246A1,CCc1cc(Nc2cc(Br)cn(C)c2=O)n[nH]1.CI>>CCc1cc(Nc2cc(Br)cn(C)c2=O)nn1C,,CN(C)C=O,,[H-].[Na+],,test
US20120088791A1,CC(C)(C)OC(=O)N1CCC[C@H](N)C1.CCOC(=O)N1CCC(=O)CC1.Cc1ccccc1C(=O)Cl>>CCOC(=O)N1CCC(N2CCC[C@H](NC(=O)c3ccccc3C)C2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04240822,ClSC(Cl)(Cl)Cl.O=[N+]([O-])c1cccc2[nH]nnc12>>O=[N+]([O-])c1cccc2c1nnn2SC(Cl)(Cl)Cl,,O,,[Na],,test
US20120283273A1,CCN(CC)S(F)(F)F.OCc1cc(Cl)ncn1>>FCc1cc(Cl)ncn1,,ClCCl,,,,test
US20090062539A1,CCN(C(C)C)C(C)C.COC(=O)c1ccc(C(=O)O)cc1.O=S(Cl)Cl>>CCN(C(C)C)C(C)C.COC(=O)c1ccc(C(=O)O)cc1.[Cl-],,COCCOC,,CN(C)C=O,,test
US20100311761A1,O=C(Cc1ccc(Cl)c(Cl)c1)N1CCNC2CCCC(N3CCCC3)C21.O=Cc1cccnc1>>O=C(Cc1ccc(Cl)c(Cl)c1)N1CCN(Cc2cccnc2)C2CCCC(N3CCCC3)C21,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05814644,O=C(O)c1cc2ccccc2[nH]1.O=S(Cl)Cl.c1ccc(CN2CCNCC2)cc1>>Cl.O=C(c1cc2ccccc2[nH]1)N1CCN(Cc2ccccc2)CC1,,Cc1ccccc1,,,,test
US20060264628A1,Cc1nc2c(s1)-c1nc(N(C)c3cccc([N+](=O)[O-])c3)ncc1CC2>>Cc1nc2ccc3cnc(N(C)c4cccc([N+](=O)[O-])c4)nc3c2s1,,Cc1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20100144825A1,Cc1ccc(Cl)cc1C(CCN(C)C(=O)OC(C)(C)C)OCCOS(C)(=O)=O.[N-]=[N+]=[N-]>>Cc1ccc(Cl)cc1C(CCN(C)C(=O)OC(C)(C)C)OCCN=[N+]=[N-],,CCOC(C)=O,,CN(C)C=O,,test
US04492691,Br.CCOC(=O)c1ccccc1Oc1ccc(Br)cc1>>BrCc1ccccc1Oc1ccc(Br)cc1,,CCOCC,,O,,test
US20060235031A1,CC(=O)Cl.NC(c1ccc2ccc(-c3ccccc3)nc2c1)c1nccnc1Cl>>CC(=O)NC(c1ccc2ccc(-c3ccccc3)nc2c1)c1nccnc1Cl,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,O,test
US04957935,CC(=O)O.CC(c1nc(N)n(-c2c(Cl)cc(C(F)(F)F)cc2Cl)n1)C(F)(F)F.COC1CCC(OC)O1>>CC(c1nc(-n2cccc2)n(-c2c(Cl)cc(C(F)(F)F)cc2Cl)n1)C(F)(F)F,,CC(=O)O,,O,O=C([O-])O.[Na+],test
US20140011856A1,CCN(CC)CCNC(=O)c1c(C)[nH]c2c1CCC/C2=C1/C(=O)Nc2ccc(F)cc21.O=S(=O)(O)O>>CCN(CC)CCNC(=O)c1c(C)[nH]c2c1CCC/C2=C1/C(=O)Nc2ccc(F)cc21.O=S(=O)(O)O,,ClCCl,,CC#N,,test
US20120208811A1,COC(OC)N(C)C.N#CCC(=O)c1cc2ccccc2n1S(=O)(=O)c1ccccc1>>CN(C)C=C(C#N)C(=O)c1cc2ccccc2n1S(=O)(=O)c1ccccc1,,C1CCOC1,,,,test
US20090181942A1,CCOC(=O)c1cnn(CC[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3-n3ccnc32)c1>>COc1cccc([C@H]2O[C@H](CCn3cc(C(=O)O)cn3)c3nccn3-c3ccc(Cl)cc32)c1OC,,CO,,Cl,[Na+].[OH-],test
US20080188528A1,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2.O=C(O)c1cccn(Cc2ccc3ccccc3c2)c1=O>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)c2cccn(Cc3ccc4ccccc4c3)c2=O)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110105429A1,Cc1cc(C(F)(F)F)nn1CC(=O)N1CCC(c2nc(C(=O)O)cs2)CC1.OC1CCCc2ccccc21>>Cc1cc(C(F)(F)F)nn1CC(=O)N1CCC(c2nc(C(=O)OC3CCCc4ccccc43)cs2)CC1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060142333A1,CCOC(=O)c1ccc(-c2ccc(F)cc2)nc1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1ccc(-c2ccc(F)cc2)nc1CBr,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US05569654,CC1=NC(N)C(=O)N(CC(=O)C(C)(C)C)c2ccccc21.N#Cc1cccc(N=C=O)c1>>CC1=NC(NC(=O)Nc2cccc(C#N)c2)C(=O)N(CC(=O)C(C)(C)C)c2ccccc21,,CC#N,,,,test
US20100179139A1,NC1CCS(=O)(=O)CC1.O=S(=O)(Cl)c1ccc(Cl)nc1>>O=S1(=O)CCC(NS(=O)(=O)c2ccc(Cl)nc2)CC1,,ClCCl,,,,test
US20110251217A1,COCCOC(=O)Cl.Cc1cc(C)n(-c2nc(Nc3ccc(Cl)cc3)c3ncn(C)c3n2)n1>>COCCOC(=O)N(c1ccc(Cl)cc1)c1nc(-n2nc(C)cc2C)nc2c1ncn2C,,CN(C)C=O,,O,[H-].[Na+],test
US20080103168A1,BrC(Br)(Br)Br.CCOc1cc(C=O)ccc1OC>>CCOc1cc(C=C(Br)Br)ccc1OC,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20130053565A1,CCCC#CCCC.Cc1ccc(S(=O)(=O)N2CC(=O)C2)cc1>>CCCC1=C(CCC)C(=O)CN(S(=O)(=O)c2ccc(C)cc2)C1,,Cc1ccccc1,,,,test
US20140221435A1,COC(=O)c1ccc(NC(=O)c2cc(Cl)c(Cl)cc2F)cc1.COc1cc(Cl)ccc1O>>COc1cc(Cl)ccc1Oc1cc(Cl)c(Cl)cc1C(=O)Nc1ccc(C(=O)O)cc1,,CN1CCCC1=O,CO,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US04278675,CCCOc1nc(N)c2ncn(Cc3ccccc3)c2n1.Cl.Nc1nc(Cl)nc2c1ncn2Cc1ccccc1>>Clc1nc(Cl)c2ncn(Cc3ccccc3)c2n1,,CCCO,,,,test
US20070173508A1,N#CC1(c2cccc(Sc3ccc4c(Cl)cc(N=C(c5ccccc5)c5ccccc5)nc4c3)c2)CCOCC1.OB(O)c1ccc(F)cc1>>N#CC1(c2cccc(Sc3ccc4c(-c5ccc(F)cc5)cc(N=C(c5ccccc5)c5ccccc5)nc4c3)c2)CCOCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20160024077A1,C=CCOC1(C)CCNCC1.COC(=O)C(=O)c1c(C)cn2nc(-c3cccc(Br)c3)cc2c1OS(=O)(=O)C(F)(F)F>>C=CCOC1(C)CCN(c2c(C(=O)C(=O)OC)c(C)cn3nc(-c4cccc(Br)c4)cc23)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110263658A1,COCCc1ccccc1-c1ccc(C(CNC(=O)OC(C)(C)C)Cc2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)c(C)c1>>COCCc1ccccc1-c1ccc(C(CN)Cc2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)c(C)c1,,ClCCl,,C1COCCO1,Cl,test
US06025375,OC1(c2nc(-c3ccccc3)c(-c3ccccc3)o2)CCCCC1Br>>c1ccc(-c2nc(C34CCCCC3O4)oc2-c2ccccc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US07829155B1,CC(O)c1ccc(CCCBr)cc1>>C=Cc1ccc(CCCBr)cc1,,Cc1ccccc1,,Cc1ccccc1S(=O)(=O)O,,test
US20100249123A1,CC(=O)NNC(=O)C(C)(C)c1ccc([N+](=O)[O-])cc1>>Cc1nnc(C(C)(C)c2ccc([N+](=O)[O-])cc2)o1,,CC#N,,O=P(Cl)(Cl)Cl,,test
US20100093706A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1CCNCC1C(=O)O>>CC1CCN(C(=O)OC(C)(C)C)CC1C(=O)O,,ClCCl,,CCN(CC)CC,,test
US03952006,CCOC(CN)OCC.CCc1cc2c(s1)NC(=S)CN=C2c1ccccc1Cl>>CCOC(CNC1=Nc2sc(CC)cc2C(c2ccccc2Cl)=NC1)OCC,,CCO,,,,test
US20080070928A1,O=[N+]([O-])c1ccc(F)c(F)c1.Oc1cccnc1>>O=[N+]([O-])c1ccc(Oc2cccnc2)c(F)c1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080312307A1,CCOC(=O)c1c(Nc2ccc(I)cc2F)[nH]c2c1CCCC2=O.COS(=O)(=O)OC>>CCOC(=O)c1c2c(n(C)c1Nc1ccc(I)cc1F)C(=O)CCC2,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100267768A1,COC(=O)Oc1cc([N+](=O)[O-])c(C(C)(C)C)cc1C(C)(C)C(N)=O.[OH-]>>CC(C)(C)c1cc(C(C)(C)C(=O)O)c(O)cc1[N+](=O)[O-],,CO,,O,,test
US20050043545A1,CC(C)CC(N)C(=O)OC(C)(C)C.O=Cc1cscn1>>CC(C)CC(N=Cc1cscn1)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,Cl,test
US03936443,O=C(Cl)C(Cl)Cl.O=C(O)CC1C=CC=CC1=NO>>O=C(O)CC1C=CC=CC1=NOC(=O)C(Cl)Cl,,ClCCl,,,,test
US20100298315A1,N#CBr.Nc1ccc(Sc2nnc3ccc(-c4ccc(F)cc4)nn23)cc1N>>Nc1nc2ccc(Sc3nnc4ccc(-c5ccc(F)cc5)nn34)cc2[nH]1,,CCO,,[Na+].[OH-],,test
US20160168096A1,CC1(C)OB(c2ccc(O)c(F)c2)OC1(C)C.CCOC(=O)CCCCBr>>CCOC(=O)CCCCOc1ccc(B2OC(C)(C)C(C)(C)O2)cc1F,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140243302A1,COc1ccc2ncc(F)c(NCC34CCC(NC(=O)OC(C)(C)C)(CC3)CO4)c2n1>>COc1ccc2ncc(F)c(NCC34CCC(N)(CC3)CO4)c2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110124634A1,CCN(CC)CCN.Cc1nc(CN2C(=O)/C(=C\c3cc(C(=O)O)c[nH]3)c3c(Cl)nc(N)nc32)sc1C>>CCN(CC)CCNC(=O)c1c[nH]c(/C=C2\C(=O)N(Cc3nc(C)c(C)s3)c3nc(N)nc(Cl)c32)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20080306046A1,CC(C)(C)OC(=O)N1CCC(Sc2ccc(OCc3cccc(F)c3)cc2)CC1>>Fc1cccc(COc2ccc(SC3CCNCC3)cc2)c1,,CCOC(C)=O,,Cl,,test
US05215878,CCOC(=O)CCCCCCCCCCOc1ccc(OC(C)=O)cc1.CCOC(=O)OCC>>CCOC(=O)CCCCCCCCCCOc1ccc(OC(=O)CC(=O)OCC)cc1,,O,,CC(C)(C)[O-].[K+],,test
US20150307480A1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.COC(=O)c1cc(Cl)cc(O)c1C>>COC(=O)c1cc(Cl)cc(OC2CCN(C(=O)OC(C)(C)C)CC2)c1C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US03954728,NN.O=NCNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=[N+]([O-])C1>>NNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=[N+]([O-])C1,,CO,,C1CCOC1,,test
US20100311714A1,CCN.Clc1ncc(Br)cn1>>CCNc1ncc(Br)cn1,,CCOC(C)=O,CO,N#N,,test
US04024134,CC(=O)OCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)[C@@H](NC(=O)C(=NO)c3ccccc3)[C@H]2SC1.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CC(=O)OCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)[C@@H](NC(=O)C(=NOC(=O)c3ccc([N+](=O)[O-])cc3)c3ccccc3)[C@H]2SC1,,CCOC(C)=O,,c1ccncc1,,test
US06900214B2,CC1=C(C#N)C(c2cccc(Br)c2)NC(=O)N1.CCN=C=O>>CCNC(=O)N1C(=O)NC(C)=C(C#N)C1c1cccc(Br)c1,,C1CCOC1,,[H-].[Na+],,test
US20150299165A1,O=C(O)C1CCCN1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1.O=C(n1ccnc1)n1ccnc1>>NC(=O)C1CCCN1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1,,CN(C)C=O,,,,test
US20070219144A1,Cc1ccc(S[C@@H]2O[C@H](COC(c3ccccc3)(c3ccccc3)c3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1>>Cc1ccc(S[C@@H]2O[C@H](CO)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1,,CCN(CC)CC,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20070197512A1,CC(C)(C)OC(=O)CN1C(=O)COc2ccccc21.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)OC(=O)CN1C(=S)COc2ccccc21,,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US20050049290A1,CC(C)CN(CC(C)C)C(=O)c1ccc(NCCCN(C)CCc2ccccn2)c(N)c1.COc1cc(N=C=S)cc(OC)c1OC.Cl>>COc1cc(Nc2nc3cc(C(=O)N(CC(C)C)CC(C)C)ccc3n2CCCN(C)CCc2ccccn2)cc(OC)c1OC.Cl,,C1CCOC1,CCOCC,N,,test
US20050222155A1,Nc1ncccc1C=O.O=C(O)c1ccc(C(=O)Cc2ccccc2)cc1>>O=C(O)c1ccc(-c2nc3ncccc3cc2-c2ccccc2)cc1,,CC(=O)O,,,,test
US20040002524A1,COc1ccc(-n2c(CC3CC3)nc3ccccc32)cc1>>Oc1ccc(-n2c(CC3CC3)nc3ccccc32)cc1,,ClCCl,,BrB(Br)Br,,test
US05541324,O=c1cnc2cc(Cl)ccc2[nH]1>>O=C1CNc2cc(Cl)ccc2N1,,CCO,,[BH4-].[Na+],,test
US20130150343A1,CNC.C[C@H]1CCC[C@@H](C)N1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4cnn(CCOS(C)(=O)=O)c4)c4ccccc43)cn12>>C[C@H]1CCC[C@@H](C)N1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4cnn(CCN(C)C)c4)c4ccccc43)cn12,,C1CCOC1,,,,test
US20090247507A1,CC(C)c1nc(CN2CCN(c3c(Br)cnc(N)c3[N+](=O)[O-])CC2)co1.COc1ccc(C=O)cc1>>COc1ccc(-c2nc3c(N4CCN(Cc5coc(C(C)C)n5)CC4)c(Br)cnc3[nH]2)cc1,,CCO,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20120302540A1,CC(C)(C)OC(=O)NC(C)(C)C(=O)N[C@H](COCc1ccccc1)C(=O)O>>CC(C)(C)OC(=O)NC(C)(C)C(=O)NC(COCC1CCCCC1)C(=O)O,[Rh],CC(C)O,,,,test
US20100298336A1,CCN1CCN(c2ccc(C=O)c(Cl)c2)CC1>>CCN1CCN(c2ccc(CO)c(Cl)c2)CC1,,CCO,,[BH4-].[Na+],,test
US20060035920A1,CCn1c(=O)c2c(C)[nH]nc2c2cc(C#CCN3CCCC3)ccc21>>CCn1c(=O)c2c(C)[nH]nc2c2cc(CCCN3CCCC3)ccc21,[Pd],CO,,,,test
US06166219,CCCCS(=O)(=O)NC(=O)c1ccc(N)c(NCc2ccc(Cl)cc2Cl)c1.COC(OC)(OC)OC>>CCCCS(=O)(=O)NC(=O)c1ccc2nc(O)n(Cc3ccc(Cl)cc3Cl)c2c1,,CC(=O)O,,,,test
US20150158846A1,C=C(C#N)C(=O)NCCOc1cccc(Nc2cc(-c3cc(F)cc(-n4ncc5c6c(sc5c4=O)CCCC6)c3COC(C)=O)cn(C)c2=O)n1>>C=C(C#N)C(=O)NCCOc1cccc(Nc2cc(-c3cc(F)cc(-n4ncc5c6c(sc5c4=O)CCCC6)c3CO)cn(C)c2=O)n1,,C1CCOC1,O,[Li]O,,test
US05484804,COc1ccccc1C1(O)CCC(c2ccccc2)(c2ccccc2)C2CNCC21.O=C(Cl)Cc1ccccc1>>COc1ccccc1C1(O)CCC(c2ccccc2)(c2ccccc2)C2CN(C(=O)Cc3ccccc3)CC21,,ClCCl,,CCN(CC)CC,Cl,test
US20160108046A1,N#Cc1ccc(-c2cc3c(ccn3S(=O)(=O)c3ccccc3)nc2Cl)cc1>>N#Cc1ccc(-c2cc3[nH]ccc3nc2Cl)cc1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20070173522A1,CC(C)(C)OC(=O)N1CCC(O)(c2ccccc2S)CC1.Clc1ccccc1I>>Clc1ccccc1Sc1ccccc1C1=CCNCC1,,Cc1ccccc1,,CC(C)(C)[O-].[K+],,test
US20100234432A1,CCC(N)=CC(=O)OC.CCOC(=O)CC(=O)c1ccc(Cl)cc1>>CCc1[nH]c(-c2ccc(Cl)cc2)cc(=O)c1C(=O)OC,,Cc1ccccc1C,,,,test
US20020042414A1,CCOC(=O)/C=C/CP(=O)(OCC)OCC.O=Cc1ccccc1>>CCOC(=O)/C=C/C=C/c1ccccc1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20030078251A1,COC(=O)CCc1sc(NC(=O)C[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3N(CC(C)(C)COC(C)=O)C2=O)nc1-c1ccccc1>>COc1cccc([C@H]2O[C@H](CC(=O)Nc3nc(-c4ccccc4)c(CCC(=O)O)s3)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20140206688A1,CC(C)S(=O)(=O)c1ccc2ncnc(Cl)c2c1.Nc1n[nH]c2ccc(F)cc12>>CC(C)S(=O)(=O)c1ccc2ncnc(Nc3n[nH]c4ccc(F)cc34)c2c1,,CC(C)O,,,,test
US20160083366A1,CC(C)(C)S(=O)/N=C/c1cc2cc(Cl)c(OCC3CC(F)(F)C3)cc2[nH]c1=O.C[Mg]Br>>CC(NS(=O)C(C)(C)C)c1cc2cc(Cl)c(OCC3CC(F)(F)C3)cc2[nH]c1=O,,CCOC(C)=O,,ClCCl,O,test
US20160176826A1,Brc1cnc(Nc2ccc(N3CCNCC3)cc2)nc1NCC1CCCO1.O=C1CCC(=O)O1>>O=C(O)CCC(=O)N1CCN(c2ccc(Nc3ncc(Br)c(NCC4CCCO4)n3)cc2)CC1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20070244118A1,CC(Br)CCCC(=O)Cl.NC1CCN(C(=O)OCc2ccccc2)CC1>>O=C(OCc1ccccc1)N1CCC(N2CCCCCC2=O)CC1,,C1CCOC1,,CCN(CC)CC,,test
US05116863,CN(C)CCN.COC(=O)Cc1ccc2c(c1)C(=O)c1ccccc1CO2>>COC(=O)Cc1ccc2c(c1)C(=NCCN(C)C)c1ccccc1CO2,Cl[Ti](Cl)(Cl)Cl,c1ccccc1,,O=C([O-])O.[Na+],,test
US04258181,CNN.CSC1=NCCN1.I>>CN(N)C1=NCCN1.I,,CCO,,,,test
US20090227553A1,C1CSCSC1.COCCBr>>COCCC1SCCCS1,,C1CCOC1,,[Li]CCCC,,test
US20160016927A1,CC(C)OB(OC(C)C)OC(C)C.FC(F)(F)C1(c2cc(Cl)cc(Cl)c2)Cc2cc(Br)c(Cl)cc2O1>>OB(O)c1cc2c(cc1Cl)OC(c1cc(Cl)cc(Cl)c1)(C(F)(F)F)C2,,C1CCOC1,,Cl,[Li]CCCC,test
US05776884,O=C1CCCC1=C1CCCC1>>OC1CCCC1=C1CCCC1,,CO,,[BH4-].[Na+],,test
US20100311795A1,COC(=O)C1(C)OCC(CCCCON=C(C)c2ccc(O)cc2)CO1.CS(=O)(=O)Cl>>COC(=O)C1(C)OCC(CCCCON=C(C)c2ccc(OS(C)(=O)=O)cc2)CO1,,ClCCl,,CCN(CC)CC,,test
US20080113978A1,CCC(CC)c1cc(C)nn2c(-c3cccn3C)c(C)nc12.O=C1CCC(=O)N1Br>>CCC(CC)c1cc(C)nn2c(-c3ccc(Br)n3C)c(C)nc12,,C1CCOC1,,O=S([O-])[O-].[Na+].[Na+],,test
US20130231319A1,F[C@H]1CCNC1.OCCCCBr>>OCCCCN1CC[C@H](F)C1,,CC#N,,N#N,O=C([O-])[O-].[K+].[K+],test
US20120157469A1,O=C(O)c1cc2ccc(Br)cc2[nH]1>>OCc1cc2ccc(Br)cc2[nH]1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080114016A1,CCOC(=O)Cl.Nc1cc2c(cc1C(=O)O)CCCC2>>CCOc1nc2cc3c(cc2c(=O)o1)CCCC3,,c1ccncc1,,,,test
US20160214971A1,Cc1cc(C(=O)NS(C)(=O)=O)c(F)cc1B1OC(C)(C)C(C)(C)O1.Clc1cc(Br)cnc1Cl>>Cc1cc(C(=O)NS(C)(=O)=O)c(F)cc1-c1cnc(Cl)c(Cl)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20080153895A1,COC(=O)c1ccc2c(C3CCCCC3)c(Br)n(CC(=O)OC(C)(C)C)c2c1.OB(O)c1ccccc1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccccc3)n(CC(=O)OC(C)(C)C)c2c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20150353505A1,c1ccc(COc2ccc3cc[nH]c3c2)cc1>>c1ccc(COc2ccc3c(c2)NCC3)cc1,,CCO,,[BH3-]C#N.[Na+],,test
US20160207893A1,COC(=O)c1ccc(C=O)cc1F.COc1cc2c(cn1)SCCNC2>>COC(=O)c1ccc(CN2CCSc3cnc(OC)cc3C2)cc1F,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20060276464A1,CC(C)c1ccc(S(=O)(=O)c2ccc(F)cc2)cc1S(=O)(=O)NC1CCNCC1.S=C=Nc1cccc2ccccc12>>CC(C)c1ccc(S(=O)(=O)c2ccc(F)cc2)cc1S(=O)(=O)NC1CCN(C(=S)Nc2cccc3ccccc23)CC1,,ClCCl,,CCN(CC)CC,,test
US20070225267A1,CC(=O)OC(C)=O.CCc1ccccc1C[C@H](N)[C@H](O)[C@H]1CO[C@@H](OCC(C)(C)C)[C@H](C)N1C(=O)OC(C)(C)C>>CCc1ccccc1C[C@H](NC(C)=O)[C@H](O)[C@H]1CO[C@@H](OCC(C)(C)C)[C@H](C)N1C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20090048249A1,COc1ccc(N)c(N)c1.O=C(O)c1n[nH]c2ncc(Br)cc12>>COc1ccc(N)c(NC(=O)c2n[nH]c3ncc(Br)cc23)c1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100130514A1,CC(C)(C)OC(=O)NCCOc1ccc(F)c(F)c1COc1ccc(F)c(N)c1.Cl.ClCCl>>Cl.Cl.NCCOc1ccc(F)c(F)c1COc1ccc(F)c(N)c1,,ClCCl,,,,test
US20150080438A1,COc1ccc2c(c1Cl)CCCC(c1ccccc1)=C2C#CCCCCO>>COc1ccc2c(c1Cl)CCCC(c1ccccc1)=C2CCCCCCO,[Pd],CO,,[K+].[OH-],,test
US20120329784A1,CN.O=[N+]([O-])c1cc([N+](=O)[O-])cc(S(=O)(=O)Cl)c1>>CNS(=O)(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1,,C1CCOC1,,c1ccncc1,,test
US20090203667A1,Nc1nccnc1C(=O)O>>Nc1nccnc1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060105997A1,CC(C)(C)C(=O)Cl.Fc1ccc(Cl)c(C2=CC(c3ccccc3)NC2)c1>>CC(C)(C)C(=O)N1CC(c2cc(F)ccc2Cl)=CC1c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20080114022A1,BrP(Br)Br.CS(=O)(=O)c1ccc(CO)c(Cl)c1>>CS(=O)(=O)c1ccc(CBr)c(Cl)c1,,CCOCC,O,,,test
US20160083368A1,CC(C)(C)OC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1nc(C#Cc2cncnc2)ccc1-c1ccc2c(c1)C(=O)NC2.Cl>>Cl.N[C@@H](Cc1cc(F)cc(F)c1)c1nc(C#Cc2cncnc2)ccc1-c1ccc2c(c1)C(=O)NC2,,C1COCCO1,,,,test
US04224330,CC(C)C(C(=O)O)c1cc2cc(F)ccc2s1.OCc1[nH]ccc1Cc1ccccc1>>CC(C)C(C(=O)OCc1[nH]ccc1Cc1ccccc1)c1cc2cc(F)ccc2s1,CN(C)c1ccncc1,CN(C)C=O,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20100286123A1,Fc1cc(Br)cc(Br)c1.O=C=O>>O=C(O)c1c(F)cc(Br)cc1Br,,C1CCOC1,CCOCC,CC(C)NC(C)C,[Li]CCCC,test
US20090018123A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C(NC[C@H]1CN(c2cc(F)c(N3CCC(n4cnnn4)CC3)c(F)c2)C(=O)O1)C(F)F>>O=C1O[C@@H](CNC(=S)C(F)F)CN1c1cc(F)c(N2CCC(n3cnnn3)CC2)c(F)c1,,C1CCOC1,,,,test
US20150080588A1,CC(C)(C)OC(=O)N[C@@H]1C[C@H]2OCC[C@@]2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1>>N[C@@H]1C[C@H]2OCC[C@@]2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090093483A1,BrCCCBr.CCOC(=O)Cc1ccc(Cl)cc1I>>CCOC(=O)C1(c2ccc(Cl)cc2I)CCC1,,CN(C)C=O,,[H-].[Na+],,test
US06162811,Cc1c2ccnc(C(=O)NCCN(C)C)c2cc2c3cc(OC(=O)N4CCN(C(=O)OCc5ccccc5)CC4)ccc3n(C)c12>>Cc1c2ccnc(C(=O)NCCN(C)C)c2cc2c3cc(OC(=O)N4CCNCC4)ccc3n(C)c12,[Pd],CO,,C1=CCCCC1,,test
US04826854,CCOC(=O)c1cnc2c(c1Cl)CCCCCCCC2.COc1ccc(NN)cc1>>COc1ccc(-n2nc3c4c([nH]cc-3c2=O)CCCCCCCC4)cc1,,CN1CCCC1=O,O,,,test
US20140275179A1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(O)c2ccsc12>>CCOC(=O)/C=C/c1ccc(O)c2ccsc12,,Cc1ccccc1,,,,test
US20110081365A1,CCOC(=O)CP(=O)(OCC)OCC.Cc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(C=O)cc3C)cc12>>CCOC(=O)/C=C/c1ccc(CCc2cnc3c(N)nc4cc(C)ccc4c3c2)c(C)c1,,C1CCOC1,,[H-].[Na+],,test
US20060229448A1,O=[N+]([O-])c1ccccc1-c1ccccc1[N+](=O)[O-]>>Nc1ccccc1-c1ccccc1N,[Pd],CCOC(C)=O,,,,test
US20100120778A1,CS(=O)(=O)Cl.Cc1nc2c(C(F)(F)F)cccc2nc1-c1cc(Oc2cccc(S(=O)(=O)CCCO)c2)ccc1Cl>>Cc1nc2c(C(F)(F)F)cccc2nc1-c1cc(Oc2cccc(S(=O)(=O)CCCOS(C)(=O)=O)c2)ccc1Cl,,ClCCl,,CCN(CC)CC,,test
US20130065880A1,CCOC(CCN)OCC.Cc1ccoc1C(=O)Nc1cc(Oc2ccnc(-c3cc(C(=O)O)c[nH]3)c2)ccc1F>>CCOC(CCNC(=O)c1c[nH]c(-c2cc(Oc3ccc(F)c(NC(=O)c4occc4C)c3)ccn2)c1)OCC,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150094328A1,N#Cc1ccnc2ccn(S(=O)(=O)c3ccccc3)c12>>N#Cc1ccnc2cc[nH]c12,,CCO,,[Na+].[OH-],,test
US04430265,CC(C)(C)OC(=O)N[C@@H](COCc1ccccc1)C(=O)O.NC(=O)[C@H](N)CCC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](COCc1ccccc1)C(=O)N[C@H](CCC(=O)OCc1ccccc1)C(N)=O,,CC#N,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US09248117B2,CC(C)(C)OCl.COCCOCCOCCN1C(=O)NC(C)(C)C1=O>>COCCOCCOCCN1C(=O)N(Cl)C(C)(C)C1=O,,CO,,,,test
US20110160433A1,CCCCCCCCCCCCCCCCCCCCCCOc1cc(CO)cc(OCCCCCCCCCCCCCCCCCCCCCC)c1.O=S(Cl)Cl>>CCCCCCCCCCCCCCCCCCCCCCOc1cc(CCl)cc(OCCCCCCCCCCCCCCCCCCCCCC)c1,,ClC(Cl)Cl,,CN(C)C=O,,test
US20080318975A1,CC(=O)C=O.Nc1ccc(Cl)c([N+](=O)[O-])c1N>>Cc1cnc2ccc(Cl)c([N+](=O)[O-])c2n1,,C1CCOC1,Cl,,,test
US20130072492A1,CCOC(=O)C1(C)C(=O)Nc2nc(-c3nn(CCC(F)(F)C(F)(F)F)c4cc(Cl)ccc34)nc(N)c21.NN>>CC1(C(=O)NN)C(=O)Nc2nc(-c3nn(CCC(F)(F)C(F)(F)F)c4cc(Cl)ccc34)nc(N)c21,,CO,,,,test
US05080905,CC(=O)Nc1cccc2c(=O)[nH]c3ccccc3c(=O)c12.CI>>CC(=O)Nc1cccc2c(=O)n(C)c3ccccc3c(=O)c12,,CN(C)C=O,CO,O,C[O-].[Na+],test
US20050065196A1,C1CCOC1.COC(=O)c1ccc(CN(C)c2nc(-c3ccc(N)cc3)cs2)cc1>>O=Cc1ccc(C2CCCCC2)cc1,,C1CCOC1,,,,test
US20070155744A1,O=C(NCc1ccc(F)cc1)c1nc(COC2CCCCO2)cc(OCc2ccccc2)c1OCc1ccccc1>>O=C(NCc1ccc(F)cc1)c1nc(CO)cc(OCc2ccccc2)c1OCc1ccccc1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20140371201A1,COc1cc(Br)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21.OB(O)c1cc(F)cc(F)c1>>COc1cc(-c2cc(F)cc(F)c2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US04908386,COCc1cc(C(=O)CBr)ccc1OCc1ccccc1.COc1ccc(CCOCCCCCCNCc2ccccc2)cc1>>COCc1cc(C(O)CNCCCCCCOCCc2ccc(OC)cc2)ccc1O,,C1CCOC1,CCO,,,test
US04564619,CC(=O)CC(=O)OCCCCCl.COC(=O)/C=C(/C)N.O=Cc1ccccc1C(F)(F)F>>COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCCCl)C1c1ccccc1C(F)(F)F,,CC(C)O,,,,test
US20030078267A1,CCOc1ccc(C2=NN3N=CC=CC3C2c2ccc(S(C)(=O)=O)cc2)cc1>>CCOc1ccc(-c2nn3ncccc3c2-c2ccc(S(C)(=O)=O)cc2)cc1,[Pd],ClCCl,,,,test
US20100256092A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc3c(c2)B(O)OC3CS(C)(=O)=O)CC1>>CS(=O)(=O)CC1OB(O)c2cc(OC3CCNCC3)ccc21,,CO,,CCOCC,Cl,test
US20050026964A1,Cn1cc(C(=O)O)c(Nc2ccc3ccccc3c2)cc1=O.O=C(Oc1c(F)c(F)c(F)c(F)c1F)C(F)(F)F>>Cn1cc(C(=O)Oc2c(F)c(F)c(F)c(F)c2F)c(Nc2ccc3ccccc3c2)cc1=O,,C1CCOC1,,c1ccncc1,,test
US20080167309A1,Nc1ccccc1.O=C(O)c1ncsc1NC(=O)c1c(Cl)cc(Cl)cc1Cl>>O=C(Nc1ccccc1)c1ncsc1NC(=O)c1c(Cl)cc(Cl)cc1Cl,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20080108620A1,CCOC(=O)c1ccc([C@H](C)NN)cc1.O=C(C#Cc1cc(Cl)cc(Cl)c1)c1cnc2ccccc2c1>>CCOC(=O)c1ccc([C@H](C)n2nc(-c3cc(Cl)cc(Cl)c3)cc2-c2cnc3ccccc3c2)cc1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20030166633A1,Cc1cccc(CC(=O)c2ccc3c(c2)OCO3)n1.O>>Cc1cccc(C(=O)C(=O)c2ccc3c(c2)OCO3)n1,,CS(C)=O,O,Br,O=C([O-])O.[Na+],test
US20050245527A1,CC(C)(C)OC(=O)Nc1cnccn1.CN(C)C=O>>CC(C)(C)OC(=O)Nc1nccnc1C=O,,C1CCOC1,,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US20150299189A1,CI.O=[N+]([O-])c1ccc2[nH]cc(C3CCCCC3)c2c1>>Cn1cc(C2CCCCC2)c2cc([N+](=O)[O-])ccc21,,CN(C)C=O,,O,CC(C)(C)[O-].[K+],test
US20100305133A1,CCOC(=O)CNC(=O)c1c(O)c(-c2nc(C)cs2)cc2nccnc12>>Cc1csc(-c2cc3nccnc3c(C(=O)NCC(=O)O)c2O)n1,,CCO,,[Na+].[OH-],,test
US05998433,O=S(=O)(c1ccc(C(O)c2ccccc2)cc1)N1CCc2ccoc2C1>>O=C(c1ccccc1)c1ccc(S(=O)(=O)N2CCc3ccoc3C2)cc1,,CS(C)=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20100249078A1,CCO.CCOC(=O)/C=C/c1ccc(Cc2ccccc2)cc1>>CCOC(=O)CCc1ccc(Oc2ccccc2)cc1,[Pd],,,,,test
US20070167427A1,CCc1cccc(C)c1CNc1cc(C(=O)O)cn2c(C)nnc12.CNC>>CCc1cccc(C)c1CNc1cc(C(=O)N(C)C)cn2c(C)nnc12,,C1CCOC1,CN(C)C=O,O=C(n1ccnc1)n1ccnc1,,test
US20160237067A1,Cc1ccc(S(=O)(=O)N(C)C)cc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)cc1.Cl>>Cc1ccc(S(=O)(=O)N(C)C)cc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)cc1.Cl,,C1COCCO1,,CC#N,,test
US20070142446A1,CCNCC.COc1cccc2c(-c3nnc(CCl)o3)cn(CC3CCCCC3)c12>>CCN(CC)Cc1nnc(-c2cn(CC3CCCCC3)c3c(OC)cccc23)o1.Cl,,C1CCOC1,,,,test
US20140371202A1,O=C1CC2(CCNCC2)Oc2ccc(Br)cc21.O=CO>>O=CN1CCC2(CC1)CC(=O)c1cc(Br)ccc1O2,,Cc1ccccc1,,,,test
US20160102080A1,Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cc(B4OC(C)(C)C(C)(C)O4)cnc3N)cc2)c1>>Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cc(B(O)O)cnc3N)cc2)c1,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20060116364A1,C1CCNCC1.CCN(C(=O)CCl)c1cc(OC)ccc1C1CCc2cc(OC)ccc2C1>>CCN(C(=O)CN1CCCCC1)c1cc(OC)ccc1C1CCc2cc(OC)ccc2C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US06028086,COc1ccc(C(=O)Cl)cc1OCCCCCCCCCCCc1ccccc1.Nc1cc(Cl)ncc1Cl>>COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)cc1OCCCCCCCCCCCc1ccccc1,,C1CCOC1,,Cl,[H-].[Na+],test
US20060148858A1,CC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO.CCOC(=O)C(C)(C)Oc1ccc(OC)c(O)c1>>COc1ccc(OC(C)(C)C(=O)O)cc1OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1C(C)C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20070135631A1,C[N+]1([O-])CCOCC1.O=C(NC1CC(F)(F)C1)N[C@@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(F)c(/C=C/c2ccccc2)c1>>O=Cc1cc([C@@](Cc2ccccc2)(NC(=O)NC2CC(F)(F)C2)c2cc(F)cc(OC(F)(F)C(F)F)c2)ccc1F,,ClCCl,,,,test
US05885990,N=C(N)c1ccc2c(CC(N)=O)c(O)ccc2c1.O=C([O-])O>>N=C(N)c1ccc2c(CC(=O)O)c(O)ccc2c1,,O,,Cl,,test
US06046189,CC(=O)Cl.CCOC(=O)c1c(CN(CC)CC)nc2sc3c(c2c1-c1ccc(OC)c(OC)c1)CCNC3>>CCOC(=O)c1c(CN(CC)CC)nc2sc3c(c2c1-c1ccc(OC)c(OC)c1)CCN(C(C)=O)C3,,O,,C1CCOC1,CCN(CC)CC,test
US20070166809A1,O=C(O)CC1=CC(OC2CCCCO2)CC1=O.Oc1ccc2ccccc2c1>>O=C(CC1=CC(O)CC1=O)Oc1ccc2ccccc2c1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20130116232A1,CCOC(=O)c1c(OC)ccc(OC)c1F>>COc1ccc(OC)c(C(=O)O)c1F,,CO,O,[Li+].[OH-],,test
US20070129379A1,Cl.Cn1nnc(-c2cc(F)ccc2C#N)n1>>Cl.NCc1ccc(F)cc1-c1nn[nH]n1,[Pd],CCO,,,,test
US20140296230A1,COc1ccc(CN2C(=O)N(C)C(C)(c3ccccc3)c3ccccc32)cc1>>CN1C(=O)Nc2ccccc2C1(C)c1ccccc1,,ClCCl,O=C(O)C(F)(F)F,O,,test
US06878712B1,C[C@@](O)(C(=O)N1CCC(N)CC1)C(F)(F)F.N#Cc1ccc(C(=O)Cl)cc1>>C[C@@](O)(C(=O)N1CCC(NC(=O)c2ccc(C#N)cc2)CC1)C(F)(F)F,,CCOC(C)=O,,CCN(CC)CC,,test
US20140371199A1,CN1CCNCC1.N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)O)c(F)c4)nn23)cc1>>CN1CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc(C#N)cc5)n4n3)cc2F)CC1,,CN(C)C=O,O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100144739A1,C[C@@H](NC(=O)OC(C)(C)C)c1nnc2ccc(Nc3cccc(Cl)c3)nn12.O=C=Nc1cccnc1>>C[C@@H](NC(=O)Nc1cccnc1)c1nnc2ccc(Nc3cccc(Cl)c3)nn12,,ClCCl,O=C(O)C(F)(F)F,CCN(C(C)C)C(C)C,,test
US04681883,Brc1nccs1.NCCCOc1cccc(CN2CCCCC2)c1>>c1cc(CN2CCCCC2)cc(OCCCNc2nccs2)c1,,c1ccncc1,,,,test
US05939360,COC(=O)c1ccc(S(C)(=O)=O)c(C)c1C.O=C1CCC(=O)N1Br>>COC(=O)c1ccc(S(C)(=O)=O)c(CBr)c1C,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US06184225B2,COc1cc2c(=O)[nH]cnc2cc1OCCCN1CCOCC1.Cc1cc(F)c(N)cc1O>>COc1cc2c(Nc3cc(O)c(C)cc3F)ncnc2cc1OCCCN1CCOCC1,CN(C)C=O,CC(C)O,,O=S(Cl)Cl,,test
US05344843,CCOC(=O)C(=O)c1ccc(O)cc1.O=C(CBr)N1CCN(CCc2ccccc2C(F)(F)F)CC1>>CCOC(=O)C(=O)c1ccc(OCC(=O)N2CCN(CCc3ccccc3C(F)(F)F)CC2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20060252741A1,FC1(F)CC[C@H](c2ccc(Br)cc2)C1.O=C=O>>O=C(O)c1ccc([C@H]2CCC(F)(F)C2)cc1,,C1CCOC1,CCOCC,[Li]CCCC,,test
US20070244156A1,CCN(CC)C(=O)CN(c1ccc(C)cc1)S(=O)(=O)c1ccc2c(c1)CN(C=O)CC2.Cc1ccc(N(CC(=O)O)S(=O)(=O)c2ccc3c(c2)CNCC3)cc1>>CCN(CC)C(=O)CN(c1ccc(C)cc1)S(=O)(=O)c1ccc2c(c1)CNCC2,,O=CO,,CCNCC,,test
US20030045558A1,CCOC(=O)C(C)(C)Oc1ccc(OCCc2nc(-c3ccc(-c4c(C)noc4C)cc3)oc2C)cc1>>Cc1noc(C)c1-c1ccc(-c2nc(CCOc3ccc(OC(C)(C)C(=O)O)cc3)c(C)o2)cc1,,C1CCOC1,CCO,CCOC(C)=O,[Na+].[OH-],test
US20140350019A1,CC(C)OC(=O)CBr.Cc1cc(CNc2c(F)ccc(O)c2C)cc(-c2cccc(F)c2)c1>>Cc1cc(CNc2c(F)ccc(OCC(=O)OC(C)C)c2C)cc(-c2cccc(F)c2)c1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20080125411A1,C1CSCCN1.Cl.ClCCCI>>Cl.ClCCCN1CCSCC1,[Zn],C1CCOC1,CCOCC,,,test
US20040224939A1,CC(=O)NC[C@H]1CO1.CCOC(=O)Nc1ccc2c(c1)CCCCC2=O>>CC(=O)NCC1CN(c2ccc3c(c2)CCCCC3=O)C(=O)O1,,C1CCOC1,,[Li]CCCC,,test
US04492692,CN=C=O.NCCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)n1>>CNC(=O)NCCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)n1,,CCOCC,,,,test
US20070254937A1,CC(=O)OC(C)=O.CC(C)CCON=O.COC(=O)c1cc(N)c(C)s1>>COC(=O)c1cc2c(cnn2C(C)=O)s1,,CCOC(C)=O,Cc1ccccc1,CC(=O)[O-].[K+],,test
US20140275482A1,BrCCCOc1ccccc1.O=C(Cl)c1ccc(I)cc1>>O=C(c1ccc(I)cc1)c1ccc(OCCCBr)cc1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(N(C)C)nc1-c1ccccc1>>CCCC(C(=O)O)c1c(C)nc(N(C)C)nc1-c1ccccc1,,C1CCOC1,,[Na+].[OH-],,test
US20060223850A1,CC(C)(c1cc(-c2cccc(-c3sc(C(=O)O)nc3-c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1)S(C)(=O)=O.CC(N)=NO>>Cc1noc(-c2nc(-c3ccc(S(C)(=O)=O)cc3)c(-c3cccc(-c4cc(C(C)(C)S(C)(=O)=O)cc5cccnc45)c3)s2)n1,,CN(C)C=O,,O,O=C(n1ccnc1)n1ccnc1,test
US20140228357A1,CN1CCN(C(=O)COc2ccc(C34CC5CC(CC(C5)C3)C4)cc2)CC1.Cl>>C[NH+]1CCN(C(=O)COc2ccc(C34CC5CC(CC(C5)C3)C4)cc2)CC1.[Cl-],,CCOCC,,,,test
US05236619,CCCCCCC(F)CO.Cc1ccc(S(=O)(=O)Cl)cc1>>CCCCCCC(F)COS(=O)(=O)c1ccc(C)cc1,,c1ccncc1,,Cl,,test
US20130116243A1,CI.C[C@H]1Oc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)cc2NC1=O>>C[C@H]1Oc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)cc2N(C)C1=O,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20060194859A1,COC(=O)C1(CC(=O)c2ccc(-c3ccc([N+](=O)[O-])cc3)cc2)CCCC1>>COC(=O)C1(CC(=O)c2ccc(-c3ccc(N)cc3)cc2)CCCC1,[Fe],CCO,,Cl,,test
US20120208815A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCc1cc(Cl)cc(N)n1>>CCc1cc(Cl)cc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n1,CN(C)c1ccncc1,ClCCl,,,,test
US04395406,CI.CN(C)CCn1cc(Cl)cnc1=O>>C[N+](C)(C)CCn1cc(Cl)cnc1=O.[I-],,CC#N,,,,test
US20140309225A1,O=C/C(Br)=C(/Br)C(=O)O.O=[N+]([O-])[O-].[Na+]>>O=CC(C=O)=[N+]([O-])[O-].[Na+],,O,,CCO,,test
US20140235614A1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.CCOC(=O)c1cn[nH]c1>>CCOC(=O)c1cnn(C2CCN(C(=O)OC(C)(C)C)CC2)c1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20130225524A1,COc1ncc(B(O)O)c(OC)n1.NC(=O)c1cnc2ccc(Br)cc2c1Nc1cccc(C(=O)O)c1>>COc1ncc(-c2ccc3ncc(C(N)=O)c(Nc4cccc(C(=O)O)c4)c3c2)c(OC)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US07211587B2,COc1cc2nccc(Oc3cc(C)c(N)cc3C)c2cc1OC.Nc1nnc(C2CC2)s1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3cc(C)c(NC(=O)Nc4nnc(C5CC5)s4)cc3C)c2cc1OC,,ClC(Cl)Cl,O,CCN(C(C)C)C(C)C,,test
US04919708,CCOC(=O)NC(=O)C(F)F.COc1cc(NN)c(F)cc1Cl>>COc1cc(-n2nc(C(F)F)[nH]c2=O)c(F)cc1Cl,,Cc1ccccc1C,,O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3,,test
US20160120841A1,COc1ccc(C(C)=O)c(O)c1.O=C(O)C1CCCO1>>COc1ccc(C(C)=O)c(OC(=O)C2CCCO2)c1,CN(C)C=O,CCOC(C)=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20110028390A1,CCO.CCc1nn(C(C)=O)c2c(OC(C)=O)cc(C(=O)[O-])cc12>>CCOC(=O)c1cc(O)c2[nH]nc(CC)c2c1,,CCOC(C)=O,,[H-].[Na+],,test
US04145432,CCOC(=O)CC(=O)C(OCC)OCC.COc1ccccc1C=O>>CCOC(=O)C(=Cc1ccccc1OC)C(=O)C(OCC)OCC,C1CCNCC1,c1ccccc1,,,,test
US20020147333A1,CCOC(=O)C(=O)CC(C)=O.CCc1cc(C(=O)O)nn1CC.NNCCO>>CCOC(=O)c1cc(C)n(CCO)n1,,ClCCl,,,,test
US20130274260A1,CCOC(=O)c1cccc(Nc2ccccc2)c1>>O=C(O)c1cccc(Nc2ccccc2)c1,,C1COCCO1,O,[Na+].[OH-],,test
US20050107371A1,CC(C)(C)OC(=O)C1COc2cc(O)ccc2C1.Cc1oc(-c2cccs2)nc1CCOS(C)(=O)=O>>Cc1oc(-c2cccs2)nc1CCOc1ccc2c(c1)OC(C(C)(C)C)C(C(=O)O)C2,,CC#N,CCOCC,O=C([O-])[O-].[K+].[K+],,test
US20120108568A1,CC1(C)CC[C@H](c2cc(F)ccc2F)N1.CCOC(=O)c1cnn2ccc(Cl)nc12>>CCOC(=O)c1cnn2ccc(N3[C@@H](c4cc(F)ccc4F)CCC3(C)C)nc12,,CC(C)O,,CCN(C(C)C)C(C)C,Cl,test
US20100168418A1,CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCNCC1.O=CCn1c(=O)ccc2cc([N+](=O)[O-])ccc21>>CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)ccc3cc([N+](=O)[O-])ccc32)CC1,,CC(=O)O,ClC(Cl)Cl,O=C([O-])O.[Na+],,test
US20090209607A1,CCc1sc(C(=O)O)cc1-c1c(C)cnn1C.N[C@@H](Cc1ccccc1C(F)(F)F)CN1C(=O)c2ccccc2C1=O>>CCc1sc(C(=O)N[C@@H](Cc2ccccc2C(F)(F)F)CN2C(=O)c3ccccc3C2=O)cc1-c1c(C)cnn1C,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US05877199,BrCc1ccccc1.CCOC(=O)c1ccc2c([nH]c3ccccc32)c1C>>CCOC(=O)c1ccc2c3ccccc3n(Cc3ccccc3)c2c1C,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US04849400,C=Cc1ccccc1.Cc1ccccc1>>Cc1ccccc1C(C)c1ccccc1,,O,,O=S(=O)(O)O,[Na+].[OH-],test
US20090291946A1,O=C(O[C@H]1CC[C@@H](N2CC[C@]3(CCCN(C(=O)OCc4ccccc4)C3)C2=O)CC1)c1ccccc1>>O=C(O[C@@H]1CC[C@H](N2CC[C@]3(CCCNC3)C2=O)CC1)c1ccccc1,[Pd],,,CO,,test
US05783522,COc1cc(-c2ncc(C(F)(F)F)cc2Cl)ccc1Cl>>Oc1cc(-c2ncc(C(F)(F)F)cc2Cl)ccc1Cl,,O,,Br,,test
US20060004048A1,CC(C)(C)OC(=O)OC(C)(C)C.CCOC(Cc1ccc(-c2cccc(CNC)c2)cc1)C(=O)OC>>CCOC(Cc1ccc(-c2cccc(CNCC(=O)OC(C)(C)C)c2)cc1)C(=O)OC,,ClCCl,,CCN(CC)CC,,test
US20090181947A1,C=C(CNCc1ccc(Cl)nc1)CC1OC(=O)C=C1N1CCCC1>>C=C1CC2OC(=O)C=C2N(Cc2ccc(Cl)nc2)C1,,CC(=O)O,,,,test
US04766222,COC(=O)CCCC(=O)Cl.C[N+](C)(C)CC(O)CC(=O)[O-]>>COC(=O)CCCC(=O)C(O)(CC(=O)[O-])C[N+](C)(C)C.[Cl-],,O=C(O)C(F)(F)F,,CCOCC,,test
US20120157448A1,O=C1CCC(C(=O)O)C(Cc2ccc(Br)cc2)C1>>O=C1CCC2C(=O)c3cc(Br)ccc3CC2C1,,O,,,,test
US20140094450A1,COC(=O)c1ccc(NCC2CCCCC2)c(NC(=O)Cc2cccs2)c1>>COC(=O)c1ccc2c(c1)nc(Cc1cccs1)n2CC1CCCCC1,,C1COCCO1,,Cl,,test
US20110130398A1,CC(C)(C)OC(=O)Nc1ccc(N)cc1.CCOC(=O)CBr>>CCOC(=O)CNc1ccc(NC(=O)OC(C)(C)C)cc1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20090018103A1,Br[Mg]c1ccccc1.CON(C)C(=O)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)c2ccccc2)C1,,C1CCOC1,,Cl,,test
US05434150,COC(=O)CCNC(=O)c1ccc(NCCCN2CCSCC2)c(N)c1.N#Cc1ccc(C(=O)Cl)cc1>>COC(=O)CCNC(=O)c1ccc2c(c1)nc(-c1ccc(C#N)cc1)n2CCCN1CCSCC1,,CC(=O)O,,Cl,,test
US20130210804A1,COC(=O)[C@H]1CC[C@H]2C(=O)Nc3ccccc3C(=O)N2C1>>O=C(O)[C@H]1CC[C@H]2C(=O)Nc3ccccc3C(=O)N2C1,,CO,,Cl,[Li+].[OH-],test
US20060025433A1,CC(C)(C)OC(=O)CNC1CCC(CNc2nc(NCc3ccccc3OC(F)(F)F)ncc2[N+](=O)[O-])CC1>>O=C(O)CN[C@@H]1CC[C@@H](CNc2nc(NCc3ccccc3OC(F)(F)F)ncc2[N+](=O)[O-])CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100168122A1,CCOC(=O)CCCCn1c(=O)c2[nH]c(Cl)nc2n(CC)c1=O>>CCn1c(=O)n(CCCCC(=O)O)c(=O)c2[nH]c(Cl)nc21,,CO,,O,[Li+].[OH-],test
US20130252936A1,NN.O=C(c1ccccc1)c1c(Cl)nnc(-c2ccccc2)c1Cl>>Clc1c(-c2ccccc2)nnc2[nH]nc(-c3ccccc3)c12,,CCO,,O,,test
US20160068515A1,CC1(C)OC[C@H](CCl)O1.O=c1[nH]ncn1-c1ccc(Br)cc1F>>CC1(C)OC[C@H](Cn2ncn(-c3ccc(Br)cc3F)c2=O)O1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150152113A1,COc1ccc(OC)c(C2CCN(c3cnnc(NNC(=O)CC4CC4)c3Cl)CC2)c1>>COc1ccc(OC)c(C2CCN(c3cnn4c(CC5CC5)nnc4c3Cl)CC2)c1,,CC#N,,O=P(Cl)(Cl)Cl,,test
US20090111796A1,COc1ccc(Cl)cc1C[C@H](CNC(=O)OC(C)(C)C)C(=O)O.N>>COc1ccc(Cl)cc1C[C@H](CNC(=O)OC(C)(C)C)C(N)=O,,C1CCOC1,,O,O=C(n1ccnc1)n1ccnc1,test
US20130252333A1,COc1ccc(F)cc1CC(Cl)C=O.NC(N)=S>>COc1ccc(F)cc1N,,CCO,,,,test
US20090186879A1,NCCCN.O=[N+]([O-])c1ccc(Cl)c(N=C(Cl)Cl)c1>>O=[N+]([O-])c1ccc(Cl)c(N=C2NCCCN2)c1,,C1CCOC1,,,,test
US20150274661A1,COC(=O)CBr.O=C(Nc1cc(F)cc(F)c1)c1cc2cc(-c3cccnc3)ccc2[nH]1>>COC(=O)CN1CCCC(c2ccc3[nH]c(C(=O)Nc4cc(F)cc(F)c4)cc3c2)C1,,CCOC(C)=O,,,,test
US20090005270A1,COc1ccc(CCNCCCC(C#N)(c2ccc(OC)c(OC)c2)C(C)C)cc1OC>>COc1ccc(CCNCCCC(C#N)(c2ccc(OC)c(OC)c2)C(C)C)cc1OC,,O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20110207965A1,C=[N+](C)C.CC(=O)c1cccc(C(F)(F)F)c1.[I-]>>CN(C)CCC(=O)c1cccc(C(F)(F)F)c1.I,,CCO,,Cl,,test
US20030055042A1,CCOC(=O)C(=O)CC(C)=O.NO>>CCOC(=O)c1cc(C)on1,,CCO,,Cl,O=C([O-])O.[Na+],test
US20080108663A1,CCS(=O)(=O)Cl.N#CC1(CC2CC2)CCNCC1>>CCS(=O)(=O)N1CCC(C#N)(CC2CC2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20070010511A1,COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CCC3c3ccc(OCCN)cc3)cc21.O=C(O)Cc1ccccc1F>>COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CCC3c3ccc(OCCNC(=O)Cc4ccccc4F)cc3)cc21,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20050154023A1,CN1CCCC(OS(C)(=O)=O)C1.[N-]=[N+]=[N-]>>CN1CCCC(N=[N+]=[N-])C1,,CN(C)C=O,,O,,test
US20090099220A1,CCOC(=O)CCCOc1ccccc1OCCCBr.CCc1nc(N)nc(N)c1O>>CCc1nc(N)nc(N)c1OCCCOc1ccccc1OCCCC(=O)O,,CN(C)C=O,O,[Li+].[OH-],,test
US20110105514A1,CC(C)(C)OC(=O)NCCBr.Ic1nc(CC2CC2)[nH]c1I>>CC(C)(C)OC(=O)NCCn1c(CC2CC2)nc(I)c1I,,CO,ClCCl,,,test
US20070244092A1,CC(C)(C)c1nc2cc(S(=O)(=O)N3CC(N)C3)ccc2n1CC1CCC(F)(F)CC1.O=C(Cl)C1CC1>>CC(C)(C)c1nc2cc(S(=O)(=O)N3CC(NC(=O)C4CC4)C3)ccc2n1CC1CCC(F)(F)CC1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US04226773,CC(=O)N1CCN=C1Nc1cc(C)nn1-c1ccccc1.Cl>>Cc1cc(NC2=NCCN2)n(-c2ccccc2)n1.Cl,,CO,,,,test
US04215139,CCOC(=O)Cl.NCCOc1ccc(Oc2ccc(Cl)cc2)cc1>>CCOC(=O)NCCOc1ccc(Oc2ccc(Cl)cc2)cc1,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US04868194,O=C(c1ccc(-n2ccnc2)cc1)C1CCN(Cc2ccncc2)CC1>>OC(c1ccc(-n2ccnc2)cc1)C1CCN(Cc2ccncc2)CC1,,CO,,O,[BH4-].[Na+],test
US20100324000A1,O=c1ccc2c([C@@H](O)CNCCc3ccc(OCC45CC6CC(CC(C6)C4)C5)cc3)ccc(OCc3ccccc3)c2[nH]1>>O=c1ccc2c([C@@H](O)CNCCc3ccc(OCC45CC6CC(CC(C6)C4)C5)cc3)ccc(O)c2[nH]1,[Pd],,,,,test
US20100311744A1,CC(C)(OCc1n[nH]c2ccccc12)C(=O)O.O=C(Cl)c1ccccc1>>CC(C)(OCc1nn(C(=O)c2ccccc2)c2ccccc12)C(=O)O,,CC(C)=O,O,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US03941821,CCOC(=O)C(O)c1ccc(-c2ccccc2N)cc1.CI>>CCOC(=O)C(O)c1ccc(-c2ccccc2NC)cc1,,c1ccncc1,,,,test
US03966766,BrP(Br)Br.OCCOCCOCCO>>OCCOCCOCCO.[Br-].[Br-],,c1ccncc1,,,,test
US20020119979A1,CC(C)(C)OC(=O)NC(Cc1cccnc1)C(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1>>NC(Cc1cccnc1)C(=O)N1CCN(C(c2ccccc2)c2ccccc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050245514A1,CCOC(C)OC1CCC(C)C(O)C=CC(C)C(/C(C)=C/C=C/C(C)(CC2OC2C(C)C(CC)OC(C)OCC)OC(C)OCC)OC(=O)C1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCOC(C)OC1CCC(C)C(Oc2ccc([N+](=O)[O-])cc2)C=CC(C)C(/C(C)=C/C=C/C(C)(CC2OC2C(C)C(CC)OC(C)OCC)OC(C)OCC)OC(=O)C1C(=O)O,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US04306065,COc1ccccc1OC1CCNC1.Clc1nc(-c2ccccc2)nc2ccccc12>>COc1ccccc1OC1CCN(c2nc(-c3ccccc3)nc3ccccc23)C1,,CC(C)O,,,,test
US20150274691A1,Cc1cc(C)c(-c2c(OC(=O)C(C)(C)C)cc(CCSc3nccs3)oc2=O)c(C)c1>>Cc1cc(C)c(-c2c(O)cc(CCSc3nccs3)oc2=O)c(C)c1,,CCO,,[Na+].[OH-],,test
US20050165063A1,CC(=O)O.CCCN(CCC)c1ccc(NC(=O)c2ccc(CNCc3ncc[nH]3)cc2)cc1.Cn1ccnc1C=O>>CCCN(CCC)Cc1ccc(NC(=O)c2ccc(CN(Cc3ncc[nH]3)Cc3nccn3C)cc2)cc1,,CC(=O)O,CO,[Na+].[OH-],,test
US20120232051A1,CC(C)(C)OC(=O)Nc1cc(C(=O)O)cc(C(F)(F)F)c1.CNc1cnccc1-c1ccccc1C>>Cc1ccccc1-c1ccncc1N(C)C(=O)c1cc(NC(=O)OC(C)(C)C)cc(C(F)(F)F)c1,,CCCCCCC,CCOC(C)=O,,,test
US04714492,Cc1cc(=O)c(C(=O)[O-])c(-c2ccc(Cl)cc2)n1CC(=O)O>>Cc1cc(=O)c(C(=O)O)c(-c2ccc(Cl)cc2)n1CC(=O)O,,[Na+],[OH-],,,test
US20120046295A1,Cc1ccc(S(=O)(=O)n2cc(-c3cc(-c4ccccc4)no3)c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc32)cc1>>CC(C)S(=O)(=O)c1ccc(-c2cnc3[nH]cc(-c4cc(-c5ccccc5)no4)c3n2)cc1,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20100240718A1,CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(=O)CCCCC(=O)OC)c3cc(C(=O)OC)ccc32)cc1.CO.COC(OC)OC>>CCCCCCCCc1ccc(OCC(Cn2cc(C(=O)CCCCC(=O)OC)c3cc(C(=O)OC)ccc32)(OC)OC)cc1,O=S(=O)(O)O,,,,,test
US20160024097A1,Cc1ccc(C#N)c(S(=O)(=O)Cl)c1.ClCCl.Nc1ccc(-c2cc3[nH]nc(N)c3cn2)cc1>>Cc1ccc(C#N)c(S(=O)(=O)Nc2ccc(-c3cc4[nH]nc(C)c4cn3)cc2)c1,,c1ccncc1,,Cl,,test
US20110183953A1,CC(C)Oc1ccc(-c2ccc(-c3cccc4c3CC[C@H]4NC(=O)OC(C)(C)C)s2)cc1C#N>>CC(C)Oc1ccc(-c2ccc(-c3cccc4c3CC[C@H]4N)s2)cc1C#N,,C1COCCO1,,Cl,,test
US20120071479A1,CC(C)(C)OC(=O)COc1ccc(CCC(=O)OCc2ccccc2)cc1Cl>>CC(C)(C)OC(=O)COc1ccc(CCC(=O)O)cc1Cl,[Pd],C1CCOC1,,,,test
US20080051395A1,O=C1CCc2ccc([N+](=O)[O-])cc2C1.[NH4+]>>NC1CCc2ccc([N+](=O)[O-])cc2C1,,CO,,[BH3-]C#N.[Na+],,test
US20130096118A1,Cc1c(-c2cnc(C(N)=O)c3[nH]c4cc(NC(=O)OCC[Si](C)(C)C)ccc4c23)cccc1N1Cc2ccc(Cl)cc2C1=O>>Cc1c(-c2cnc(C(N)=O)c3[nH]c4cc(N)ccc4c23)cccc1N1Cc2ccc(Cl)cc2C1=O,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20090018132A1,Nc1c(C(=O)O)cccc1[N+](=O)[O-].O=C1CCC(=O)N1Cl>>Nc1c(C(=O)O)cc(Cl)cc1[N+](=O)[O-],,CC(=O)O,,O,,test
US20060235035A1,CCN(C(C)C)C(C)C.CCN=C=NCCCN(C)C.COc1cc(NC(=O)Nc2cccc(Oc3ccccc3)c2)ccc1C(=O)O>>COc1cc(NC(=O)Nc2cccc(Oc3ccccc3)c2)ccc1C(=O)NCCCN(C)C(C)C,,CCOC(C)=O,ClCCl,On1nnc2ccccc21,,test
US20110212967A1,CNC(=O)c1ccc(-c2cnc(N)nn2)cn1.O=C1CCC(=O)N1C(O)C(Cl)Cc1ccc2ncccc2c1>>CNC(=O)c1ccc(-c2cnc3ncc(Cc4ccc5ncccc5c4)n3n2)cn1,,OCCO,,,,test
US04855292,CCOC(=O)Cc1c(F)ccc(F)c1F>>O=C(O)Cc1c(F)ccc(F)c1F,,CCO,,Cl,[Na+].[OH-],test
US04588722,CCOC(=O)N1CCC(N=C=S)CC1.Nc1cnccc1NCc1ccc(F)cc1>>CCOC(=O)N1CCC(NC(=S)Nc2cnccc2NCc2ccc(F)cc2)CC1,,C1CCOC1,,,,test
US06294580B1,COCCl.Cc1c[nH]c(-c2ccccc2)n1>>COCn1cc(C)nc1-c1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US20110015157A1,COC(=O)c1ccc([C@H](C)N2CC[C@](CCCO)(c3ccccc3)OC2=O)cc1>>C[C@@H](c1ccc(CO)cc1)N1CC[C@](CCCO)(c2ccccc2)OC1=O,,C1CCOC1,,CO,[BH4-].[Na+],test
US20160168121A1,COc1ccc2c(Cl)ncnc2c1.O=[N+]([O-])c1ccc(O)c(F)c1>>COc1ccc2c(-c3ccc([N+](=O)[O-])cc3F)ncnc2c1,,O,,c1ccc(Oc2ccccc2)cc1,,test
US20080194557A1,FC(F)(F)c1ccc2nccc(Cl)c2c1.Nc1cccc(Cl)c1>>FC(F)(F)c1ccc2nccc(Nc3cccc(Cl)c3)c2c1,Cl,CC(C)O,,,,test
US05021481,CCON1C(C)(C)CC(OC(=O)c2ccccc2)CC1(C)C>>CCON1C(C)(C)CC(O)CC1(C)C,,CO,,[Na+].[OH-],,test
US20070213364A1,CCOC(=O)CCc1ccc(OCc2ccc(Cn3nc(-c4ccc(F)cc4)cc3CCc3ccccc3)cc2)cc1F>>O=C(O)CCc1ccc(OCc2ccc(Cn3nc(-c4ccc(F)cc4)cc3CCc3ccccc3)cc2)cc1F,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20050256158A1,COc1ccc(C(=O)N2c3ccccc3[C@H](N)C[C@@H]2C)cc1.O=C1CCCC1>>COc1ccc(C(=O)N2c3ccccc3[C@H](NC3CCCC3)C[C@@H]2C)cc1,,CO,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05929120,BrBr.CCOC(=O)c1ccc(CCC(C)=O)cc1>>CCOC(=O)c1ccc(CCC(=O)CBr)cc1,,CCO,,,,test
US20060247210A1,Nc1nc2ccc(S(N)(=O)=O)cc2s1>>Nc1ccc(S(N)(=O)=O)cc1S,,O,,Cl,[Na+].[OH-],test
US20090264445A1,COC(=O)[C@H](CC(C)C)N1CC(Oc2cccc(C(F)(F)F)c2)=CC1=O>>CC(C)C[C@@H](C(=O)O)N1CC(Oc2cccc(C(F)(F)F)c2)=CC1=O,,C1CCOC1,O,[Li+].[OH-],,test
US20020111333A1,CCCn1c(=O)nc(SC)c2[nH]c(C34CCC(CCC(=O)OC)(CC3)CC4)nc21.CC[C@@H](N)CO>>CCCn1c(=O)nc(NC(CC)CO)c2[nH]c(C34CCC(CCC(=O)OC)(CC3)CC4)nc21,,CS(C)=O,,,,test
US20100004312A1,COC(=O)C[C@@H]1COc2cc(O)ccc21.Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(CO)c1>>COC(=O)C[C@@H]1COc2cc(OCc3cccc(-c4c(C)cc(OCCCS(C)(=O)=O)cc4C)c3)ccc21,,CCCCCC,Cc1ccccc1,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20120022045A1,CC(C)(C)[Si](C)(C)Cl.O=C1CCC(CO)CC1>>CC(C)(C)[Si](C)(C)OCC1CCC(=O)CC1,,O,,CN(C)C=O,c1c[nH]cn1,test
US20040235919A1,CC(C(=O)O)c1ccc(N2CCOC2=O)cc1.CC(C)c1cnc(N)s1>>CC(C)c1csc(NC(=O)C(C)c2ccc(N3CCOC3=O)cc2)n1,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20030144293A1,C[Si](C)(C)C=[N+]=[N-].O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(-n2ncc(=O)[nH]c2=O)ccc1Cl>>Cn1c(=O)cnn(-c2ccc(Cl)c(C(=O)NCC34CC5CC(CC(C5)C3)C4)c2)c1=O,,C1COCCO1,,CO,,test
US20150126492A1,CC(C)(C)OC(=O)N[C@H](CC(=O)N1CCN(C(=O)OCc2ccccc2)CC1)c1ccc(F)cc1>>CC(C)(C)OC(=O)N[C@H](CC(=O)N1CCNCC1)c1ccc(F)cc1,[Pd],CCO,,ClC(Cl)Cl,,test
US20160000760A1,NC(=O)c1ccc(B(O)O)cc1.Nc1nc(Nc2cc(Cl)c(Br)c(Cl)c2)n[nH]1>>NC(=O)c1ccc(-c2c(Cl)cc(Nc3n[nH]c(N)n3)cc2Cl)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20140142083A1,CC(=O)CC(=O)C(F)(F)F.N#CCC(N)=O>>Cc1cc(C(F)(F)F)c(C#N)c(=O)[nH]1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20020077329A1,CCCCc1nc2c(C)nc(C)cc2n1-c1ccc(CCN(C(=O)[O-])S(=O)(=O)c2ccc(C)cc2)cc1.Cc1ccc(S(=O)(=O)O)cc1>>CCCCc1nc2c(C)nc(C)cc2n1-c1ccc(CCN(C(=O)O)S(=O)(=O)c2ccc(C)cc2)cc1.Cc1ccc(S(=O)(=O)O)cc1,,CO,,,,test
US20040176399A1,CCn1c(N)c(N)c(=O)[nH]c1=O.O=C(O)c1cnn(Cc2cccc(C(F)(F)F)c2)c1>>CCn1c(N)c(NC(=O)c2cnn(Cc3cccc(C(F)(F)F)c3)c2)c(=O)[nH]c1=O,,CO,,CCN=C=NCCCN(C)C,Cl,test
US20120010191A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cn1cc(Br)cc(Nc2cc3n(n2)CCOC3)c1=O>>Cn1cc(B2OC(C)(C)C(C)(C)O2)cc(Nc2cc3n(n2)CCOC3)c1=O,,C1COCCO1,,ClCCl,CC(=O)[O-].[K+],test
US05216170,CCOCCOc1ccc(C=O)cn1.CC[N+](=O)[O-]>>CCOCCOc1ccc(C=C(C)[N+](=O)[O-])cn1,,CC(=O)O,O,C,O=C[O-].[NH4+],test
US20080234255A1,CC(C)CCN1CC(C)C(=O)N(C)c2cnc(Cl)nc21.COc1cc(C(=O)NC2CCN(C)CC2)ccc1N>>COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(CCC(C)C)CC(C)C(=O)N2C,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20090136473A1,COc1ccc(C=O)c(F)c1Br>>COc1ccc(CO)c(F)c1Br,,ClCCl,,CO,[BH4-].[Na+],test
US20110124637A1,CC1(C)OCC(COc2cccc(-c3nc4c(C(=O)Nc5nccs5)cccc4[nH]3)c2)O1>>O=C(Nc1nccs1)c1cccc2[nH]c(-c3cccc(OCC(O)CO)c3)nc12,,C1CCOC1,,Cl,,test
US20160207957A1,CC(C)N=C=NC(C)C.CCCCCCCCCCCCCC(=O)O.N[C@@H](CCC(=O)O)C(=O)O>>CCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)O)C(=O)OC(C)(C)C,,CN(C)C=O,,On1nnc2ccccc21,,test
US20030130270A1,COCC(COC)OS(C)(=O)=O.Oc1ccccc1>>COCC(COC)Oc1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070072865A1,NC(=O)c1ccccc1.O=C(Cl)C(=O)Cl.O=C1OC(c2ccccc2)(c2ccccc2)C2CNCCN12>>O=C(NC(=O)N1CCN2C(=O)OC(c3ccccc3)(c3ccccc3)C2C1)c1ccccc1,,ClCCCl,,,,test
US20110130453A1,CC(C)(N)Cc1ccc(F)cc1.COC(=O)Cc1cccc(Oc2ccc(Br)cc2C=O)c1>>COC(=O)Cc1cccc(Oc2ccc(Br)cc2CNC(C)(C)Cc2ccc(F)cc2)c1,CC(=O)O,CCOC(C)=O,CO,[BH3-]C#N.[Na+],,test
US20100099695A1,CCCC[C@@H]1NC(=O)OCCCCCc2cccc(c2)CO[C@@H]2C[C@@H](C(=O)OCC[Si](C)(C)C)N(C2)C1=O>>CCCC[C@@H]1NC(=O)OCCCCCc2cccc(c2)CO[C@@H]2C[C@@H](C(=O)O)N(C2)C1=O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20160115126A1,CCOC(=O)N1CCc2c(Br)cc(F)cc2C1>>Fc1cc(Br)c2c(c1)CNCC2,,O,OCCO,[K+].[OH-],,test
US07247645B2,O=C(CCl)CC(=O)OCCC(c1ccccc1)c1ccccc1.OCCc1ccccn1>>O=C(COCCc1ccccn1)CC(=O)OCCC(c1ccccc1)c1ccccc1,,C1CCOC1,,CO,[H-].[Na+],test
US20040009995A1,CC(C)(CN)CO.CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cnc(Cl)c(Br)c1.O=C(O)C(F)(F)F>>CSc1sc(C(=N)N)cc1S(=O)(=O)c1cnc(NCC(C)(C)CO)c(Br)c1.O=C(O)C(F)(F)F,,C1CCOC1,,ClCCl,,test
US20100022518A1,CC(C)(C)OC(=O)CCNc1ccc(Cl)c(Cl)c1.COC(=O)CBr>>COC(=O)CN(CCC(=O)OC(C)(C)C)c1ccc(Cl)c(Cl)c1,,CC#N,,Cc1cccc(C)n1,,test
US20140200227A1,CC(=O)OC1CCc2c1ncc(N)c2N1CCC[C@H](NC(=O)OC(C)(C)C)C1.Nc1ncc(-c2c(F)cccc2F)nc1C(=O)O>>CC(=O)OC1CCc2c1ncc(NC(=O)c1nc(-c3c(F)cccc3F)cnc1N)c2N1CCC[C@H](NC(=O)OC(C)(C)C)C1,,ClCCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090105306A1,CC(C)(C)C(=O)CC#N.NNC[C@@H]1CCCO1>>CC(C)(C)c1cc(N)n(C[C@@H]2CCCO2)n1,,CCO,,,,test
US20020151534A1,COC(=O)c1ccc(NC2CCCC2)c(C)c1>>Cc1cc(C(=O)O)ccc1NC1CCCC1,,CO,,[Na+].[OH-],,test
US20120028964A1,C1CCOC1.CC(C)(C)OC(=O)N1CCOC1(C)C.Oc1cccc(OCc2ccccc2)c1>>CC[C@@H](C[C@H]1COC(C)(C)N1C(=O)OC(C)(C)C)Oc1cccc(OCc2ccccc2)c1,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130123231A1,II.OCCC1CCCCC1>>ICCC1CCCCC1,,C1CCOC1,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160060257A1,CN(C)C=O.COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CC4CNCC4C3)cc12.N#CN.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(=O)[O-].COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CC4CN(C(=O)NC#N)CC4C3)cc12.[NH4+],,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20070208007A1,CC(C)N(C(=O)CCCCNC(=O)OC(C)(C)C)c1cc(C#N)ccc1N>>CC(C)n1c(CCCCN)nc2ccc(C#N)cc21,,CO,,C1COCCO1,Cl,test
US20090163512A1,C=C(N=Cc1cc(F)ccc1C)O[Si](C)(C)C.CC(C)(C)OC(=O)N1C(=O)/C(=C\c2cc(Cl)ccc2OCC#N)c2ccc(Cl)cc21>>Cc1ccc(F)cc1C1NC(=O)CC(c2cc(Cl)ccc2OCC#N)C12C(=O)Nc1cc(Cl)ccc12,,Cc1ccccc1,,,,test
US04110333,O=c1[nH]c2cc(Cl)ccc2n1C1CCNCC1.O=c1sc2ccccc2n1CCCBr>>O=c1sc2ccccc2n1CCCN1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1,,CC(=O)CC(C)C,O,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US03962223,O=C(Cc1ccc([N+](=O)[O-])cc1)N[C@H]1C(=O)N2C(C(=O)[O-])=C(C3CCCC3)CS[C@H]12>>O=C(Cc1ccc([N+](=O)[O-])cc1)N[C@H]1C(=O)N2C(C(=O)O)=C(C3CCCC3)CS[C@H]12,,O=C(O)C(F)(F)F,,,,test
US20150225439A1,CC(C)(C)OC(=O)NCCOCCN(CCOCCNC(=O)OC(C)(C)C)CC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NCCOCCN(CCOCCNC(=O)OC(C)(C)C)CC(=O)O,,CO,,,,test
US04072498,CC(C)(C)OCl.Cc1cc(-c2ccccc2)nn1C(C)C(=O)N(C)C.ClC(Cl)(Cl)Cl>>CC(C(=O)N(C)C)n1cc(Cl)c(-c2ccccc2Cl)n1,,CC(=O)O,,BrBr,,test
US20100130489A1,FC(F)(F)c1cc2nc(Cl)c3nccn3c2cc1Br.NCCCO>>OCCCNc1nc2cc(C(F)(F)F)c(Br)cc2n2ccnc12,,C1COCCO1,,,,test
US04046753,Cl.c1ccc(NNC2=NCCS2)cc1>>Cl.c1ccc(NNC2=NCCS2)cc1,,CO,,CCOCC,,test
US20110124634A1,COc1c(C)cnc(CN2C(=O)Cc3c(Cl)nc(N)nc32)c1C.O=Cc1ccc(C(=O)O)[nH]1>>COc1c(C)cnc(CN2C(=O)/C(=C\c3ccc(C(=O)O)[nH]3)c3c(Cl)nc(N)nc32)c1C,,CCO,,C1CCNCC1,,test
US05332729,CCOP(=O)(CC1CCCCC1)C[C@@H](O)CNC(C)c1cccc(C#N)c1.O=P(O)(O)O.[Li+].[OH-]>>CC(NC[C@H](O)CP(=O)([O-])CC1CCCCC1)c1cccc(C(=O)O)c1.[Li+],,CCO,O,,,test
US20150291598A1,CNc1ccc(C#N)cc1.O=C(O)c1cn2c(-c3ccc(C(F)(F)F)cc3)cnc2cn1>>CN(C(=O)c1cn2c(-c3ccc(C(F)(F)F)cc3)cnc2cn1)c1ccc(C#N)cc1,,CN(C)C=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20100216827A1,CCOC(=O)C(C)C.COc1c(F)cc(C=O)cc1F>>CCOC(=O)C(C)(C)C(O)c1cc(F)c(OC)c(F)c1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20030114660A1,CC(C)(C)[Si](C)(C)Cl.OC[C@@H]1CO1>>CC(C)(C)[Si](C)(C)OC[C@@H]1CO1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20110105460A1,CCN(CC)CC.CCNC(=O)c1ccc([N+](=O)[O-])c(F)c1>>CCNC(=O)c1ccc([N+](=O)[O-])c(NC)c1,,CC#N,,,,test
US20140094471A1,CC(=O)O[BH-](OC(C)=O)OC(C)=O.CC(C)(C)OC(=O)NC1CNC1.O=C1CCOC1>>CCCCOC(=O)NC1CN(C2CCOC2)C1,,ClCCl,,O=C([O-])O.[Na+],,test
US20040077669A1,Clc1cc(Cl)ncn1.OB(O)c1ccccc1F>>Fc1ccccc1-c1cc(Cl)ncn1,,O,,COCCOC,,test
US20080182802A1,CCc1ccc(Cc2ccc3c(c2)[C@]2(CCO3)O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1>>CCc1ccc(Cc2ccc3c(c2)[C@]2(CCO3)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1,[Pd],CO,,,,test
US05236927,CC(=O)O.Cc1ccc([N+](=O)[O-])cc1F.O=S(=O)(O)O>>O=C(O)c1ccc([N+](=O)[O-])cc1F,,O,,,,test
US04867915,C#CCBr.Cc1ccc(O)cc1>>C#CCOc1ccc(C)cc1,,O,,[Na+].[OH-],,test
US08563505B2,C=Cc1cccc(-c2cccc(Br)c2)c1.COC(=O)[C@@H]1CC(=O)CN1C(=O)OCC[Si](C)(C)C>>C=Cc1cccc(-c2cccc([C@]3(O)C[C@@H](C(=O)OC)N(C(=O)OCC[Si](C)(C)C)C3)c2)c1,,C1CCOC1,ClCCl,[Mg],,test
US20100249191A1,Nc1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20070249670A1,CCCC/C=C(/NC(=O)OCc1ccccc1)C(=O)OC>>CCCCCC(N)C(=O)OC,[Pd],CCO,,,,test
US20040248875A1,Cn1c(N)c(CCCNC=O)c[n+]1CC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)/C(=N\OC(C)(C)C(=O)O)c3nsc(N)n3)[C@H]2SC1>>Cn1c(N)c(CCCN)c[n+]1CC1=C(C(=O)[O-])N2C(=O)[C@@H](NC(=O)/C(=N\OC(C)(C)C(=O)O)c3nsc(N)n3)[C@H]2SC1,,CO,,Cl,O=C([O-])O.[Na+],test
US20130225589A1,COC(OC)N(C)C.CSC(=N)N.O=C1CC(=O)N(c2ccccc2Cl)c2ccccc21>>CSc1ncc2c(=O)n(-c3ccccc3Cl)c3ccccc3c2n1,,CC(=O)O,,O=S(=O)(O)O,,test
US20150252030A1,COC(=O)CBr.Oc1cccc(-c2ccco2)c1>>COC(=O)COc1cccc(-c2ccco2)c1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140249126A1,CCn1nc(C(=O)OC)c(=O)c2cc(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)cc21>>CCn1nc(C(=O)O)c(=O)c2cc(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)cc21,,CO,,O,[K],test
US07566784B2,CC(C)(C)OC(=O)c1cc2[nH]ccc2cn1.O=[N+]([O-])c1ccc(F)cc1>>CC(C)(C)OC(=O)c1ccc2ccn(-c3ccc([N+](=O)[O-])cc3)c2n1,,CN(C)C=O,,[H-].[Na+],,test
US20140187542A1,CC(C)(C)[Si](C)(C)OC[C@H]1CNC(=O)C1.CCOC(=O)COc1ccc(Br)nc1[N+](=O)[O-]>>CCOC(=O)COc1ccc(N2C[C@H](CO[Si](C)(C)C(C)(C)C)CC2=O)nc1[N+](=O)[O-],[Cu]I,CCOC(C)=O,Cc1ccccc1,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US20030100555A1,Cc1cc(C)c(/C=C2\C(=O)Nc3ccccc32)[nH]1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>Cc1cc(C)c(/C=C2\C(=O)N(C(=O)Cl)c3ccccc32)[nH]1,,C1CCOC1,,,,test
US20040067945A1,CCCOc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1-c1nn2c(CCC)nc(C)c2c(=O)[nH]1.Cl>>CCCOc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1-c1nn2c(CCC)nc(C)c2c(=O)[nH]1.Cl,,CCOCC,,ClCCl,,test
US20030149004A1,Cc1cc(C)c(C(C)(C)CCO)c(OC(=O)CCCBr)c1>>Cc1cc(C)c(C(C)(C)CC=O)c(OC(=O)CCCBr)c1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US04556737,CCOCC(O)COc1ccc(N)cc1.CSCC(=O)Cl>>CCOCC(O)COc1ccc(NC(=O)CSC)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20040259912A1,COC(=O)c1cc([N+](=O)[O-])ccc1O.OC(c1ccc(F)cc1)c1ccccc1Cl>>COC(=O)c1cc([N+](=O)[O-])ccc1OC(c1ccc(F)cc1)c1ccccc1Cl,,CN(C)C=O,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US06133287,CN1CC=C(c2c[nH]c3c(F)cc(F)cc23)CC1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)n2cc(C3=CCN(C)CC3)c3cc(F)cc(F)c32)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US05039752,C=CC(=C)C.c1ccccc1>>C=CC(=C)C.C=CC=C,,c1ccccc1,,[Li]C(C)CC,,test
US20020143182A1,CC(C)OB(OC(C)C)OC(C)C.COc1ccc(Br)cc1C(C)(C)C>>COc1ccc(B(O)O)cc1C(C)(C)C,,C1CCOC1,CCOCC,Cl,[Li]CCCC,test
US20120190701A1,COC(=O)c1cc(Br)cc(C)c1C.COC/C=C/B1OC(C)(C)C(C)(C)O1>>COC/C=C/c1cc(C)c(C)c(C(=O)OC)c1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US05998433,C=O.CNC.O=C1c2ccccc2S(=O)(=O)c2cc(C(=O)N3CCc4ccoc4C3)ccc21>>CN(C)Cc1cc2c(o1)CN(C(=O)c1ccc3c(c1)S(=O)(=O)c1ccccc1C3=O)CC2,,CC(=O)O,,,,test
US06251912B1,COCCC(C)(N)C#CC(=O)O.Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1>>COCCC(C)(N)C#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1,,C1CCOC1,c1ccncc1,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20110319380A1,CC(C)(C)OC(=O)N1CCCC1(C)CNC(=O)CCl>>CC1(CNC(=O)CCl)CCCN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100168103A1,CN1CCN(C(=O)C2(c3ccccc3)CCNCC2)CC1.O=C=NC(c1ccccc1)c1ccccc1>>CN1CCN(C(=O)C2(c3ccccc3)CCN(C(=O)NC(c3ccccc3)c3ccccc3)CC2)CC1,,ClCCl,,,,test
US20030055047A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc3n2Cc2ccccc2N(C(=O)C2=CC=C(c4ccccc4)C(C)(C(F)(F)F)C2)C3)CC1.Cl>>CC1(C(F)(F)F)CC(C(=O)N2Cc3ccc(C(=O)N4CCNCC4)n3Cc3ccccc32)=CC=C1c1ccccc1.Cl,,CCOCC,,CCOC(C)=O,,test
US20050143375A1,C1CCOC1.Cc1nc(C#Cc2ccnc(Cl)c2)cn1-c1cc(F)cc(F)c1>>Cc1nc(C#Cc2ccnc(Cl)c2)c(C)n1-c1cc(F)cc(F)c1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20120053175A1,CN1CCNCC1.Cc1ccc(S(=O)(=O)n2cc(-c3ccc4[nH]ccc4c3)c3cc(-c4ccc(C=O)cc4)cnc32)cc1>>CN1CCN(Cc2ccc(-c3cnc4[nH]cc(-c5ccc6[nH]ccc6c5)c4c3)cc2)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20110230495A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.COC(=O)c1sccc1Br>>COC(=O)c1sccc1C1=CCN(C(=O)OC(C)(C)C)CC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20020013369A1,CCc1ccc(N)c(CC(=O)O)c1.[I-]>>CCc1ccc(I)c(CC(=O)O)c1,,Cl,O,O=N[O-].[Na+],,test
US20130137680A1,N#CCCNN=C1CCOCC1>>Nc1ccnn1C1CCOCC1,,CCCO,,[Na+].[OH-],,test
US20160046583A1,CC(C)(C)CN.O=C(O)c1ccc2cncc(-c3ccc(Cl)cc3)c2c1>>CC(C)(C)CNC(=O)c1ccc2cncc(-c3ccc(Cl)cc3)c2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04188400,O=S(Cl)Cl.OCc1coc(Cc2ccccc2)c1>>ClCc1coc(Cc2ccccc2)c1,,Cc1ccccc1,,c1ccncc1,,test
US05801253,CCOC(=O)/C=C(C)/C=C/C(Br)=C(/C)c1ccc2c(c1)C(C)(C)CCC2(C)C>>CC(/C=C/C(Br)=C(/C)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C\C(=O)O,,C1CCOC1,CCO,[Na+].[OH-],,test
US20090227570A1,C=CS(C)(=O)=O.O=C(Nc1ccc2nc(N[C@@H]3CCc4ccccc43)ccc2c1)NC1CCNCC1>>CS(=O)(=O)CCN1CCC(NC(=O)Nc2ccc3nc(N[C@@H]4CCc5ccccc54)ccc3c2)CC1,,C1CCOC1,,CCN(CC)CC,CCOC(C)=O,test
US20090264445A1,CCOC(=O)C=C(CNC(CC(C(F)(F)F)C(F)(F)F)C(=O)OC)Oc1ccccc1Cl>>COC(=O)C(CC(C(F)(F)F)C(F)(F)F)N1CC(Oc2ccccc2Cl)=CC1=O,,CC#N,,,,test
US20030195221A1,BrCc1ccccc1.N#CC1CC1>>N#CC1(Cc2ccccc2)CC1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20090253684A1,CN(C)C(=O)c1cc(Br)cc(C#CCCCCCc2cccc(OCCCC(=O)O)c2CCC(=O)O)c1.OB(O)c1ccc(O)cc1>>CN(C)C(=O)c1cc(C#CCCCCCc2cccc(OCCCC(=O)O)c2CCC(=O)O)cc(-c2ccc(O)cc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O,O=C([O-])[O-].[K+].[K+],test
US20050107437A1,N#CCCl.Oc1cccc(Br)n1>>N#CCOc1cccc(Br)n1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20160016948A1,CC(C)Nc1cc(Cl)ncc1N.O=C(Cl)CCl>>CC(C)n1c(CCl)nc2cnc(Cl)cc21,,ClCCl,,CCN(CC)CC,,test
US20130296305A1,CI.COC(=O)c1c[nH]c2c1CCCC2=O>>COC(=O)c1cn(C)c2c1CCCC2=O,,O,,CN(C)C=O,,test
US20040009995A1,CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(B(O)O)c1.Cc1cc([N+](=O)[O-])cnc1I>>CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2ncc([N+](=O)[O-])cc2C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,,test
US20080090845A1,CCOC(=O)[C@H](C#N)NC=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)c1ncsc1N,,c1ccccc1,,,,test
US20070135452A1,CCC=O.CCOC(C)=O.CO.Cc1cc(C)c(Nc2nc3cccc(N)c3n2C)c(C)c1.[BH3-]C#N>>CCCN(CCC)c1cccc2nc(Nc3c(C)cc(C)cc3C)n(C)c12,,CCOC(C)=O,CO,CC(=O)O,,test
US20080153852A1,Cc1cc(Br)cs1.O=Cc1ccccc1B(O)O>>Cc1cc(-c2ccccc2C=O)cs1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US06200987B1,CCOC(=O)N1C(=O)c2ccccc2C1=O.COC(=O)CC(N)c1ccccc1>>COC(=O)CC(c1ccccc1)N1C(=O)c2ccccc2C1=O,,CC#N,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20120028961A1,CC(C)(C)CCO.N#Cc1ccc(Cl)nc1>>CC(C)(C)CCOc1ccc(C#N)cn1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20100331320A1,C=C(C)CC(O)(CCCl)c1ccc(F)cc1.C[C@H](N=C=O)c1ccccc1Br>>C=C(C)CC1(c2ccc(F)cc2)CCNC(=O)O1,,C1CCOC1,CCOC(C)=O,C1CCC2=NCCCN2CC1,,test
US20130131035A1,Fc1ccc(OC2CNC2)cc1.Fc1ccnc(Cl)c1>>Fc1ccc(OC2CN(c3ccnc(Cl)c3)C2)cc1,,CC(C)O,,CCN(C(C)C)C(C)C,Cl,test
US20070161622A1,CC(=O)OC(C)=O.COCCCOc1cc(C[C@@H](C[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CN)C(C)C)ccc1OC>>COCCCOc1cc(C[C@@H](C[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CNC(C)=O)C(C)C)ccc1OC,,ClCCl,,O,c1ccncc1,test
US20100145047A1,CC(C)(C)OC(=O)N1CC[C@H](N)C1.O=[N+]([O-])c1ccc(Cl)nc1>>O=C(O)N1CC[C@H](Nc2ccc([N+](=O)[O-])cn2)C1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20110144110A1,CCOC(=O)CCc1ccc(-c2ccc(-n3ccnc3)cc2)n1-c1ccc(CN)cc1C>>Cc1cc(CN)ccc1-n1c(CCC(=O)O)ccc1-c1ccc(-n2ccnc2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20120059028A1,CCCC(C(=O)OCC)c1c(CC)nc2sc3c(c2c1-c1ccc(C)cc1)CCCC3>>CCCC(C(=O)O)c1c(CC)nc2sc3c(c2c1-c1ccc(C)cc1)CCCC3,,CCO,CO,[Na+].[OH-],,test
US05631378,CN(C)[NH+]=CCl.CO/N=C(\C(=O)O)c1csc(N)n1.[Cl-]>>CO/N=C(\C(=O)Cl)c1csc(N=CN(C)C)n1.Cl,,C1CCOC1,,CC(C)OC(C)C,,test
US20030166664A1,Cc1ccc([N+](=O)[O-])cc1CC(=O)O.Clc1cccc2c(C3CCNCC3)c[nH]c12>>Cc1ccc([N+](=O)[O-])cc1CC(=O)N1CCC(c2c[nH]c3c(Cl)cccc23)CC1,,C1CCOC1,CN(C)C=O,O=C(n1ccnc1)n1ccnc1,,test
US20070112068A1,BrCC1CC1.N#CC(C#N)CCC(F)(F)F>>N#CC(C#N)(CCC(F)(F)F)CC1CC1,,CS(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US04975445,Brc1cccnc1.O=C1CCC(N2CCN(c3ccccn3)CC2)CC1>>OC1(c2cccnc2)CCC(N2CCN(c3ccccn3)CC2)CC1,,C1CCOC1,CCOCC,[Li]CCCC,,test
US20140088153A1,CCOC(=O)c1cc(C2(Cl)CC2)nn1C.O=C1CCC(=O)N1Cl>>CCOC(=O)c1c(Cl)c(C2(Cl)CC2)nn1C,,CN(C)C=O,O,,,test
US06121251,COC(=O)Cl.Cc1ccccc1NO>>COC(=O)N(O)c1ccccc1C,,ClCCl,,O=C([O-])O.[Na+],,test
US20130116260A1,CC[Mg]Br.COC(=O)c1c(C#N)nc(N[C@@H]2CCCC[C@@H]2NC(=O)OC(C)(C)C)nc1Nc1cccc(C)c1>>Cc1cccc(Nc2nc(N[C@@H]3CCCC[C@@H]3NC(=O)OC(C)(C)C)nc3c2C(=O)NC32CC2)c1,,CCOC(C)=O,CCOCC,,,test
US20130225554A1,O=C(NNc1cccnc1)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1>>O=C(NNc1cccnc1)[C@@H]1CC[C@@H]2CN1C(=O)N2O,[Pd],CO,,,,test
US04624953,COC(=O)N1CCNCC1.Fc1ccc(C(CCCCl)c2ccc(F)cc2)cc1>>COC(=O)N1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1.Cl,,CCO,,O,O=C([O-])O.[Na+],test
US20080125468A1,COC(=O)CCNC(=O)c1ccc(OC(CC2CCCCC2)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2)cc1>>O=C(O)CCNC(=O)c1ccc(OC(CC2CCCCC2)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2)cc1,,C1CCOC1,,Cl,[Li+].[OH-],test
US06303556B1,CC(C)=CCCC(C)=CC(C)O>>CC(C)CCCC(C)CC(C)O,[Pd],CCCCCC,,,,test
US20100113542A1,CCCCN(C)C(=O)c1cc(-c2nnc(O)n2-c2ccccc2C)c(OCc2ccccc2)cc1OCc1ccccc1>>CCCCN(C)C(=O)c1cc(-c2nnc(O)n2-c2ccccc2C)c(O)cc1O,[Pd],C1CCOC1,,[H][H],,test
US05130318,CCCC[Sn](CCCC)(CCCC)n1nnc(-c2ccccc2-c2ccc(COc3cc(CC)nc4c3CCCC4)c(Cl)c2)n1.FC(F)(F)c1cc(OCc2ccc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc2)c2c(n1)CCCC2>>Cl.c1cnc2c(c1)CCCC2,,Cc1ccccc1C,,,,test
US04904791,COC(C)(C)O/N=C(\C(=O)O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1.Cc1cc(=O)n2nc(SCC3=C(C(=O)OC(c4ccccc4)c4ccccc4)N4C(=O)[C@@H](N)[C@H]4SC3)sc2n1>>COC(C)(C)O/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CSc3nn4c(=O)cc(C)nc4s3)CS[C@H]12)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20110110889A1,Ic1c[nH]c2ncccc12.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(c1ccccc1)n1cc(I)c2cccnc21,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120252805A1,COc1cccc(-c2c(Br)sc3nc(C)cc(NS(C)(=O)=O)c23)c1.OB(O)c1cn[nH]c1>>COc1cccc(-c2c(-c3cn[nH]c3)sc3nc(C)cc(NS(C)(=O)=O)c23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US04053477,CC(=O)OC(C)=O.O=C(O)C(=O)O.c1ccc(C2CCN(CCC(c3ccccc3)(c3ccccc3)c3nnn[nH]3)CC2)cc1>>Cc1nnc(C(CCN2CCC(c3ccccc3)CC2)(c2ccccc2)c2ccccc2)o1.O=C(O)C(=O)O,,CCOCC,CO,c1ccncc1,,test
US20050148624A1,CCCCC=O.COC(=O)c1c(-c2ccccc2)c2cc(Cl)ccc2c(=O)n1N>>CCCCC=Nn1c(C(=O)OC)c(-c2ccccc2)c2cc(Cl)ccc2c1=O,,CO,,CCN(CC)CC,,test
US20120309769A1,COC(=O)[C@H](C)Oc1ccc(C(C)n2c(C)c(C)c3cc(C(=O)N[C@@H](C)c4ccc(C(C)(C)C)cc4)ccc32)cc1>>Cc1c(C)n(C(C)c2ccc(O[C@@H](C)C(=O)O)cc2)c2ccc(C(=O)N[C@@H](C)c3ccc(C(C)(C)C)cc3)cc12,,CN(C)C=O,CO,[Na+].[OH-],,test
US20030105323A1,CCOC(=O)C(N)CC(C)C.Nc1nc(Cl)c2c(n1)CCCC2>>CCOC(=O)C(CC(C)C)Nc1nc(N)nc2c1CCCC2,,CCCCO,,CCN(CC)CC,Cl,test
US20040063705A1,COC(=O)C=C1CCN(C)CC1>>COC(=O)CC1CCN(C)CC1,[Pd],CCO,,,,test
US20020119992A1,CCOC(=O)CC1C=CC=CC1=O.C[Si](C)(C)C(F)(F)F>>CCOC(=O)C(O)(c1ccccc1)C(F)(F)F,,Cl,,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100273770A1,CC(C)Oc1ccc(C(=O)O)cc1Cl.CCOC(=O)CCCC1c2cccc(C(=N)NO)c2OCCN1C(=O)OC(C)(C)C>>CCOC(=O)CCCC1c2cccc(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)c2OCCN1C(=O)OC(C)(C)C,CN(C)C=O,CC#N,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20120035168A1,Cc1cc(NC(=O)OC(C)(C)C)nc(C)c1CN.O=C(O)c1ncc(Cc2ccccc2)o1>>Cc1cc(NC(=O)OC(C)(C)C)nc(C)c1CNC(=O)c1ncc(Cc2ccccc2)o1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090069300A1,BrCCC1OCCCO1.O=C1NCCc2cc(Br)ccc21>>O=C1c2ccc(Br)cc2CCN1CCC1OCCCO1,,CN(C)C=O,,[H-].[Na+],,test
US20070100150A1,CCCC1=C(O)OC(=O)C1.CC[C@H](N)C(N)=O>>CCC[C@@H]1CC(=O)N([C@@H](CC)C(N)=O)C1,,CC(C)O,,Cl,N,test
US20060287344A1,CC(C)Nc1ncc2nc(Nc3c(F)cc(F)cc3F)n(C3CCC(O)(C(=O)O)CC3)c2n1.NC1CCCC1>>CC(C)Nc1ncc2nc(Nc3c(F)cc(F)cc3F)n(C3CCC(O)(C(=O)NC4CCCC4)CC3)c2n1,,C1CCOC1,,CC(C)NC(C)C,,test
US20040058918A1,CC(C)(C)OC(=O)N1CCC(N2NC(=O)C(c3ccc(Cl)cc3)C2c2ccncc2)CC1>>CC(C)(C)OC(=O)N1CCC(n2[nH]c(=O)c(-c3ccc(Cl)cc3)c2-c2ccncc2)CC1,[Pd],CCO,,,,test
US04868301,CCOC(=O)Cc1n[nH]c(=O)c2ccccc12.N#CCCCl>>CCOC(=O)Cc1nn(CCC#N)c(=O)c2ccccc12,,CN(C)C=O,,Cl,CC(C)(C)[O-].[K+],test
US20060252812A1,O=C1N(Cc2ccccn2)c2cccc(Br)c2C1(CO)c1cc2c(cc1O)OCC2>>O=C1N(Cc2ccccn2)c2cccc(Br)c2C12COc1cc3c(cc12)CCO3,,C1COCCO1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080045521A1,COC(=O)[C@H](Cc1ccc(C#CCN(C(=O)OC(C)(C)C)c2ccccn2)cc1)NC(=O)c1c(Cl)cccc1Cl>>COC(=O)[C@H](Cc1ccc(C#CCNc2ccccn2)cc1)NC(=O)c1c(Cl)cccc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150105373A1,O=C(CBr)c1ccc(OC(F)(F)F)cc1.Oc1cncc(Br)c1>>O=C(COc1cncc(Br)c1)c1ccc(OC(F)(F)F)cc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US04859229,CC(C)Oc1cc(N=C=O)c(F)cc1Cl.CCOC(=O)/C(CC)=C(/C)N>>CCOC(=O)/C(CC)=C(/C)NC(=O)Nc1cc(OC(C)C)c(Cl)cc1F,,CN(C)C=O,,,,test
US06344570B1,C=CCC(N)CC(=O)[O-].CC(C)C[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C>>C=CCC(N)CC(=O)[O-].CN[C@@H](CC(C)C)C(=O)O,,O,,O=C(O)C(F)(F)F,,test
US20110224225A1,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](C(N)=O)C1.COc1cc(F)ccc1-c1ccnc(Cl)c1>>COc1cc(F)ccc1-c1ccnc(NC(=O)[C@@H]2CC[C@H](NC(=O)OC(C)(C)C)C2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20050153962A1,COc1cc(Nc2nc(C(=O)O)cs2)ccc1Cl.O=C(Cl)c1ccc(Cl)cc1Cl>>COc1cc(N(C(=O)c2ccc(Cl)cc2Cl)c2nc(C(=O)O)cs2)ccc1Cl,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US05019298,CC(=O)Cl.CC(O)c1ccc(-c2ccc(C(=O)OCc3ccccc3)cc2)cc1>>CC(=O)OC(C)c1ccc(-c2ccc(C(=O)OCc3ccccc3)cc2)cc1,,Cc1ccccc1,c1ccncc1,Cl,,test
US20070244087A1,CO[C@@H](C(=O)NC1CSc2ccccc2NC1=O)[C@@H]1OC(C)(C)O[C@H](/C=C/C(C)(C)C)[C@@H]1O>>CO[C@@H](C(=O)NC1CSc2ccccc2NC1=O)[C@H](O)[C@@H](O)[C@H](O)/C=C/C(C)(C)C,,C1CCOC1,,Cl,[Na+].[OH-],test
US04277395,COC(=O)C(C)C(C(F)(F)F)C1(C(C)N2C(=O)c3ccccc3C2=O)SCCCS1.Cl>>CC(C(=O)O)C(C(F)(F)F)C1(C(C)N)SCCCS1.Cl,,CCO,,NN,O,test
US06399616B1,c1ccc(CN2CCC(C3=NCCc4sccc43)CC2)cc1>>c1ccc(CN2CCC(c3nccc4sccc34)CC2)cc1,[Pd],CCO,,,,test
US20050282819A1,CC1(C)c2ccc(CCCN3CCN(c4nsc5ccccc45)CC3)cc2C(C)(C)C1O.CS(=O)(=O)O>>CC1(C)c2ccc(CCCN3CCN(c4nsc5ccccc45)CC3)cc2C(C)(C)C1OS(C)(=O)=O,,CCOC(C)=O,,,,test
US20090247507A1,Nc1ncc(Br)c(N2CCN(Cc3ccncc3)CC2)c1[N+](=O)[O-].O=Cc1ccc(CN2CCOCC2)cc1>>Brc1cnc2[nH]c(-c3ccc(CN4CCOCC4)cc3)nc2c1N1CCN(Cc2ccncc2)CC1,,CCO,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20160200704A1,CC(C)(C)OC(=O)n1cc(Cl)c2cc(CCl)ccc21.COC(=O)c1ccnc([Sn](C)(C)C)c1>>COC(=O)c1ccnc(Cc2ccc3c(c2)c(Cl)cn3C(=O)OC(C)(C)C)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,,,test
US05064564,CCCCCCCCOc1ccc(-c2ccc(CBr)cc2)cc1.CCCCCC[C@H]1C[C@]1(C#N)c1ccc(O)cc1>>CCCCCCCCOc1ccc(-c2ccc(COc3ccc([C@@]4(C#N)C[C@@H]4CCCCCC)cc3)cc2)cc1,,CN(C)C=O,,Cl,CC(C)(C)[O-].[K+],test
US04003893,CSCOC(=O)C(SCSC)c1ccccc1>>CSCSC(C(=O)O)c1ccccc1,,CCO,,[Na+].[OH-],,test
US20140066420A1,CCOC(=O)CC(=O)N1CC(COc2ccc(F)cc2C(C)(C)C)C1>>CC(C)(C)c1cc(F)ccc1OCC1CN(C(=O)CC(=O)O)C1,,C1CCOC1,,Cl,[Li+].[OH-],test
US08143428B2,COc1ccc(NS(=O)(=O)CC(=O)O)cc1O.O=Cc1cc(Cl)ccc1O>>COc1ccc(NS(=O)(=O)c2cc3cc(Cl)ccc3oc2=O)cc1O,,CC(=O)O,,,,test
US20040023995A1,CC(=O)O[C@H](C)CCCCn1c(=O)c2c(N(C)C)cc(C)nc2n(C)c1=O>>Cc1cc(N(C)C)c2c(=O)n(CCCC[C@@H](C)O)c(=O)n(C)c2n1,,CO,O,[K+].[OH-],,test
US20110207701A1,Cc1cccc(C#N)c1Br.O=C1CCC(=O)N1Br>>N#Cc1cccc(CBr)c1Br,,ClC(Cl)(Cl)Cl,,,,test
US20120184543A1,CC(=O)O.CC1(C)Cc2c(C(=O)[O-])ccc([N+](=O)[O-])c2O1>>COC(=O)c1ccc(N)c2c1CC(C)(C)O2,[Fe],CC(=O)O,,O=C([O-])[O-].[Na+].[Na+],,test
US05179085,BrCc1cccc(Br)c1.COC(=O)CN>>COC(=O)CNCc1cccc(Br)c1,,CCN(CC)CC,CO,Cl,,test
US04883798,CCI.COc1cc(C=O)ccc1O>>CCOc1ccc(C=O)cc1OC,,O,,[Na+].[OH-],,test
US05459154,Cl.NNC(=O)N(O)Cc1ccc(OCc2csc(-c3ccccc3)n2)cc1>>Cl.NNC(=O)N(O)Cc1ccc(OCc2csc(-c3ccccc3)n2)cc1,,C1CCOC1,,CCOCC,,test
US20070112044A1,NN.O=C(O)CSC(=S)c1ccccc1>>NNC(=S)c1ccccc1,,O,,[Na+].[OH-],,test
US20040116328A1,CC#CCBr.Cn1ncc2nc(N3CCN(C(=O)OC(C)(C)C)CC3)[nH]c2c1=O>>CC#CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2cnn(C)c(=O)c21,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150218092A1,COc1cc([N+](=O)[O-])ccc1OCCOC1CCCCO1>>COc1cc(N)ccc1OCCOC1CCCCO1,[Pd],CO,,,,test
US20130281434A1,COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(Br)sc2c1-c1ccc(Cl)cc1.OB(O)c1ccnc(Cl)c1>>COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(Cl)c3)sc2c1-c1ccc(Cl)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20070032478A1,O=[N+]([O-])c1ccc(NCCN2CCCC2)cc1>>Nc1ccc(NCCN2CCCC2)cc1,[Ni],CCO,,NN,O,test
US20100261673A1,N#Cc1ccc(I)cc1.Oc1cccnc1>>N#Cc1ccc(Oc2cccnc2)cc1,,CN(C)C=O,,C1CCOC1,CC(C)(C)[O-].[K+],test
US20050187236A1,CNC(=O)n1ccc2cc(Oc3ccnc(N)c3)ccc21.OCn1nnc2ccccc21>>CNC(=O)n1ccc2cc(Oc3ccnc(NC)c3)ccc21,,CCO,CN(C)C=O,[BH4-].[Na+],,test
US20050182224A1,CCCCCCCC(=O)Cl.CCOC(=O)C(C)=O>>C=C(OC(=O)CCCCCCC)C(=O)OCC,,CCOCC,,c1ccncc1,O=C([O-])O.[Na+],test
US20050153970A1,CON(C)C(=O)CCc1ccc(F)cc1>>O=CCCc1ccc(F)cc1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070105904A1,CCCCOCc1ccc(CCl)cc1.Nc1ncccc1-c1cn[nH]c1>>CCCCOCc1ccc(Cn2cc(-c3cccnc3N)cn2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04477464,O=C1NC(=O)c2ccccc21.O=C1Nc2ccccc2OCC1Cl>>O=C1Nc2ccccc2OCC1N1C(=O)c2ccccc2C1=O,,CN(C)C=O,,O,[K],test
US20120316147A1,CC(C)(N)CC(=O)N1CCOCC1>>CC(C)(N)CCN1CCOCC1,,C1CCOC1,,B,CO,test
US20070249670A1,CC(C)(C)OC(=O)[C@@H]1CCCN1.Cc1cccc(C)c1NC(=O)Nc1cc2ccccc2cc1C(=O)O>>Cc1cccc(C)c1NC(=O)Nc1cc2ccccc2cc1C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C,,CCOC(C)=O,CN(C)C=O,Cl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120190665A1,CC1(C)CO1.COc1ccc(C#N)cc1-c1[nH]ncc1NC(=O)c1cnn2cccnc12>>COc1ccc(C#N)cc1-c1nn(CC(C)(C)O)cc1NC(=O)c1cnn2cccnc12,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04960787,COC1CCC(OC)O1.Cc1cccc(C)c1N>>Cc1cccc(C)c1-n1cccc1,,CC(=O)O,,,,test
US04138488,N#CCCl.O=C(O)c1ccc(C(c2ccccc2)c2ccccc2)cn1>>N#CCOC(=O)c1ccc(C(c2ccccc2)c2ccccc2)cn1,,CC(C)=O,,CCN(CC)CC,,test
US20120258948A1,Brc1ccc(OCCC2CC(OC3CCCCO3)C2)cc1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(c2ccc(OCCC3CC(OC4CCCCO4)C3)cc2)OC1(C)C,,CCCCCCC,CCOC(C)=O,CC(=O)[O-].[K+],,test
US20050277647A1,CC(C)(C(=O)O)N1CCN(c2ccc(C(F)(F)F)cn2)CC1.CCN(C(C)C)C(C)C.CCN=C=NCCCN(C)C.ClCCl.Oc1cccc2[nH]nnc12>>CC(C)(C(=O)NC1C2CC3CC1CC(O)(C3)C2)N1CCN(c2ccc(C(F)(F)F)cn2)CC1,,CCN(C(C)C)C(C)C,,Cl,O,test
US20040048868A1,COC(=O)c1ccc(N)c(N)c1.O=Cc1n[nH]c2ccccc12>>COC(=O)c1ccc2nc(-c3n[nH]c4ccccc34)[nH]c2c1,,O=[N+]([O-])c1ccccc1,,,,test
US20120252817A1,Cl.ClCCl.Cn1cc(-c2ccc(C3(NC(=O)OC(C)(C)C)CC3)nc2)cn1>>Cl.Cl.Cn1cc(-c2ccc(C3(N)CC3)nc2)cn1,,Cl,,C1COCCO1,,test
US05747477,CC(C)(CC(=O)O)c1ccccc1.O=[N+]([O-])O>>CC(C)(CC(=O)O)c1ccc([N+](=O)[O-])cc1,,O=S(=O)(O)O,,,,test
US20060264429A1,Cc1ccc2c(N3CCN(CC(=O)c4ccc5c(c4)NC(=O)CO5)CC3)cccc2n1.[NH4+]>>Cc1ccc2c(N3CCN(CC(N)c4ccc5c(c4)NC(=O)CO5)CC3)cccc2n1,,CO,,[BH3-]C#N.[Na+],,test
US20090281311A1,Brc1ccc(-c2ccncc2)nc1.CC(C)(C)c1ccc(-c2nc(-c3ccc(Br)cc3)nc(-c3ccc(C(C)(C)C)cc3)n2)cc1>>CC(C)(C)c1ccc(-c2nc(-c3ccc(-c4ccc(-c5ccncc5)nc4)cc3)nc(-c3ccc(C(C)(C)C)cc3)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20130172339A1,CC(=O)CCl.Cc1ccc(S)cc1>>CC(=O)CSc1ccc(C)cc1,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US04011324,CCOC(=O)c1nc2nc3cc(OC)c(OC)cc3cc2c(=O)[nH]1.CN>>CNC(=O)c1nc2nc3cc(OC)c(OC)cc3cc2c(=O)[nH]1,,CCO,,,,test
US20130225552A1,CC(C)(C)OC(=O)N[C@H]1C[C@H](N)C1.O=[N+]([O-])c1cccnc1Cl>>CC(C)(C)OC(=O)N[C@@H]1C[C@@H](Nc2ncccc2[N+](=O)[O-])C1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120289474A1,CCn1cc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(-c4ccccc4)cc32)cn1.Cl>>CCn1cc(Cn2c(=O)n(C3CCNCC3)c(=O)c3sc(-c4ccccc4)cc32)cn1.Cl,,C1COCCO1,,,,test
US20030069434A1,BrC(Br)(Br)Br.C[C@]12C[C@H](F)[C@@H]3[C@H]4CCC(=O)C=C4C[C@@H](CCCCCO)[C@H]3[C@@H]1CCC2=O>>C[C@]12C[C@H](F)[C@@H]3[C@H]4CCC(=O)C=C4C[C@@H](CCCCCBr)[C@H]3[C@@H]1CCC2=O,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US06376665B1,COC(=O)[C@@H](C)N(C)C(=O)C(CC(=O)OC(C)(C)C)c1ccc(OCc2ccccc2)cc1>>COC(=O)[C@@H](C)N(C)C(=O)C(CC(=O)OC(C)(C)C)c1ccc(O)cc1,[Pd],CO,,,,test
US04542142,CC(OC(=O)[C@@H]1[C@H](/C=C\C(=O)OC(C)(C)C)C1(C)C)c1cccc(Oc2ccccc2)n1>>CC(OC(=O)[C@@H]1[C@H](/C=C\C(=O)O)C1(C)C)c1cccc(Oc2ccccc2)n1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090124802A1,Cc1cc(C#N)cc(C)c1O.Nc1nc(Cl)c2c(ccn2Cc2ccccc2)n1>>Cc1cc(C#N)cc(C)c1Oc1nc(N)nc2ccn(Cc3ccccc3)c12,,CN1CCCC1=O,O,[H-].[Na+],,test
US20020032208A1,COc1cc(COc2cc3ncnc(Oc4ccccc4)c3cc2OC)cc(Cl)n1>>COc1cc2c(=O)[nH]cnc2cc1OCc1cc(Cl)[nH]c(=O)c1,,Cl,,N,,test
US20110301142A1,CCOC(=O)Cc1ccc(OC)c(B2OC(C)(C)C(C)(C)O2)c1.Cc1noc(-c2cccc(Br)c2)c1NC(=O)OC(C)c1ccccc1Cl>>CCOC(=O)Cc1ccc(OC)c(-c2cccc(-c3onc(C)c3NC(=O)OC(C)c3ccccc3Cl)c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(C(C)c4ccc(S(C)(=O)=O)cc4)cnc3F)n2)cc1.COc1ccc(N)cn1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(C(C)c4ccc(S(C)(=O)=O)cc4)cnc3Nc3ccc(OC)nc3)n2)cc1,,C1CCOC1,ClCCl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05684004,CCN(CC)CCCCCCOc1ccc(/C(=C(\Cl)c2ccccc2)c2ccccc2)cc1.O=C(O)CC(O)(CC(=O)O)C(=O)O>>CCN(CC)CCCCCCOc1ccc(/C(=C(\Cl)c2ccccc2)c2ccccc2)cc1.O=C(O)CC(O)(CC(=O)O)C(=O)O,,CCO,,,,test
US04644075,CC(=O)OCc1c2ccccc2c(COC(C)=O)c2ccccc12.CCCCCC>>CC(=O)O[C@H](C)CC[C@@H](C)OC(C)=O,CN(C)c1ccncc1,,,CCOC(C)=O,,test
US20090208485A1,COCC[C@]1(C(=O)O)C=C[C@@H](NC(=O)OC(C)(C)C)C1>>COCC[C@]1(C(=O)O)CC[C@@H](NC(=O)OC(C)(C)C)C1,[Pd],CO,,,,test
US20140235611A1,COC(=O)C(C)(C)c1ccc(Oc2cc(Oc3ccc(F)cc3)cc([N+](=O)[O-])c2)cc1>>COC(=O)C(C)(C)c1ccc(Oc2cc(N)cc(Oc3ccc(F)cc3)c2)cc1,,CCOC(C)=O,,CO,,test
US20130165472A1,CC(=O)Nc1cc(B2OC(C)(C)C(C)(C)O2)ccn1.C[Si](C)(C)CCOCn1cc(Br)nc1-c1ccccc1Cl>>CC(=O)Nc1cc(-c2cn(COCC[Si](C)(C)C)c(-c3ccccc3Cl)n2)ccn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US05208228,CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(N=[N+]=[N-])C(OC(C)C)C3)C(C)C(O[Si](C)(C)C(C)(C)C)CC1=O)C(C)CC2OC>>CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(N=[N+]=[N-])C(OC(C)C)C3)C(C)C(O)CC1=O)C(C)CC2OC,,CC#N,CCOC(C)=O,,,test
US04505739,CC(=O)OC(C)=O.CC(C)(C)c1cc(N)n[nH]1>>CC(=O)Nc1cc(C(C)(C)C)[nH]n1,,c1ccccc1,,O,,test
US04282365,NCC(=O)O.O=C(Cl)c1ccc2c(c1)C(=O)c1ccccc1CO2>>NC(=O)c1ccc2c(c1)C(=O)c1ccccc1CO2,,CCOC(C)=O,,,,test
US20100113444A1,CCCCCCN.CCOC(=O)CN=C=O.O=C(Cl)CC(=O)Cl.O=C=NC1CCCCC1>>CCCCCCn1c(=O)c(C(=O)NCC(=O)O)c(O)n(C2CCCCC2)c1=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20010056179A1,CCc1ccccc1CCC(=O)O.O=S(Cl)Cl>>CCc1ccccc1CCC(=O)Cl,,Cc1ccccc1,,,,test
US04665092,C=[N+]=[N-].CC(=O)N[C@@H](CS)C(=O)O>>COC(=O)[C@H](CS)NC(C)=O,,CCOCC,,,,test
US20050288367A1,COC(=O)C(C)Br.Oc1ccc(OCc2ccccc2)cc1>>COC(=O)C(C)Oc1ccc(OCc2ccccc2)cc1,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060142336A1,NO.O=S(=O)(/C=C/c1ccccc1)N1CCC(OCc2cc(F)ccc2F)CC1>>O=S(=O)(CC(NO)c1ccccc1)N1CCC(OCc2cc(F)ccc2F)CC1,,C1CCOC1,O,CCOC(C)=O,,test
US20030191323A1,CC(=O)O.NS(=O)(=O)c1ccccc1NC(=O)c1ccc(C#Cc2ccccc2)cc1>>CC(=O)NS(=O)(=O)c1ccccc1NC(=O)c1ccc(C#Cc2ccccc2)cc1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20040023973A1,N#Cc1ccccc1-c1cc(-c2ccccn2)cn(CC2CCNCC2)c1=O.O=C(Cl)c1ccccc1>>N#Cc1ccccc1-c1cc(-c2ccccn2)cn(CC2CCN(C(=O)c3ccccc3)CC2)c1=O,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20140194418A1,CSc1nc(Cl)c(C(N)=O)c(Nc2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc2Cl)n1.NN>>CSc1nc(NN)c(C(N)=O)c(Nc2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc2Cl)n1,,C1COCCO1,,O,,test
US20110190351A1,COc1ccc(CC(=O)Cl)cc1.COc1ccc(N)c2nc(C3CC3)[nH]c12>>COc1ccc(CC(=O)Nc2ccc(OC)c3[nH]c(C4CC4)nc23)cc1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US04273704,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl.COC(=O)C12CC3CC(CC(N)(C3)C1C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](N)CCSC)C2>>COC(=O)C12CC3CC(CC(N)(C3)C1C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](CCSC)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C2,,C1CCOC1,CCOC(C)=O,CN1CCOCC1,Cl,test
US07538241B2,COCCCc1c(Br)c(OCOC)cc(OCOC)c1-c1ccccc1>>COCCCc1c(Br)c(O)cc(O)c1-c1ccccc1,,CCO,,Cl,,test
US20030220350A1,CN(C)S(=O)(=O)c1cccc([N+](=O)[O-])c1>>CN(C)S(=O)(=O)c1cccc(N)c1,,CCO,,Cl[Sn]Cl,,test
US03965107,BrCc1ccccc1.Cc1cc(C)c2c(=O)[nH]sc2n1>>Cc1cc(C)c2c(=O)n(Cc3ccccc3)sc2n1,,CC(C)=O,,CCN(CC)CC,,test
US20080269286A1,NC(=O)c1cc(C2CCN(Cc3ccccc3)CC2)ccc1Cl>>N#Cc1cc(C2CCN(Cc3ccccc3)CC2)ccc1Cl,,CN(C)C=O,,O=P(Cl)(Cl)Cl,,test
US20040157885A1,CC(C)(Oc1cccc(C2CCCNC2)c1)C(=O)OCc1ccccc1.NCc1ccc(C(F)(F)F)cc1.O=C(n1ccnc1)n1ccnc1>>CC(C)(Oc1cccc(C2CCCN(C(=O)NCc3ccc(C(F)(F)F)cc3)C2)c1)C(=O)OCc1ccccc1,,Cc1ccccc1,O,Cl,,test
US20090149425A1,CC(C)(C)c1cc(CO)no1.O=S(Cl)Cl>>CC(C)(C)c1cc(CCl)no1,,ClCCl,,,,test
US20040242580A1,COC(=O)SCl.O=C1CNC(c2cc(Cl)cc(Cl)c2)=NN1CC(F)(F)F>>COC(=O)SN1CC(=O)N(CC(F)(F)F)N=C1c1cc(Cl)cc(Cl)c1,,C1CCOC1,,CCN(CC)CC,,test
US20100004301A1,O=[N+]([O-])c1cccc(-c2nc3ccc([N+](=O)[O-])cc3o2)c1>>Nc1cccc(-c2nc3ccc(N)cc3o2)c1,[Pd],CC(=O)O,,[H][H],,test
US03951987,Fc1ccc(C2=CCNCC2)cc1.OCCCl>>OCCN1CC=C(c2ccc(F)cc2)CC1,,CCO,,[I-].[Na+],,test
US20160256458A1,CC(=O)N1c2ccc(Br)cc2N(C(=O)OC(C)C)C[C@@H]1C.CC1(C)OB(c2cnn(Cc3cnccn3)c2)OC1(C)C>>CC(=O)N1c2ccc(-c3cnn(Cc4cnccn4)c3)cc2N(C(=O)OC(C)C)C[C@@H]1C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20140187533A1,CC(C)(C)[Si](C)(C)OCc1nc2cc(C(F)(F)F)cc(C(F)(F)F)c2[nH]1>>OCc1nc2cc(C(F)(F)F)cc(C(F)(F)F)c2[nH]1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150057240A1,BrCc1ccccc1.OC1C=CC(O)CC1>>OC1C=CC(OCc2ccccc2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20030216570A1,CCOC(=O)/C=C/c1cc(Br)cc2c1OCC2(C)C>>CCOC(=O)CCc1cccc2c1OCC2(C)C,[Pd],CCO,CCOC(C)=O,,,test
US20120238582A1,CCOC(=O)C(CCC(F)F)(CCC(F)F)c1ccc2nc(N)nc(C(=O)N3Cc4ccccc4C3)c2c1>>Nc1nc(C(=O)N2Cc3ccccc3C2)c2cc(C(CCC(F)F)(CCC(F)F)C(=O)O)ccc2n1,,C1CCOC1,,[Na+].[OH-],,test
US20030134854A1,CO.COc1ccc(N2CCOCC2)c2sc(NC(=O)c3ccc(Cl)nc3)nc12>>COc1ccc(C(=O)Nc2nc3c(OC)ccc(N4CCOCC4)c3s2)cn1,,C1COCCO1,CN(C)C=O,[H-].[Na+],,test
US20120264737A1,CN(C)C=O.Cc1cc(C2CCC2)c(I)cc1C(=O)O>>Cc1cc(C2CCC2)c(C=O)cc1C(=O)O,,CCOCC,,C1CCOC1,[Li]CCCC,test
US05229516,CCOC(=O)C(C)c1ccc2c(c1)[nH]c1ccc(OCc3ccccc3)cc12>>CCOC(=O)C(C)c1ccc2c(c1)[nH]c1ccc(O)cc12,[Pd],CCO,,,,test
US04085118,O=C(O)CCC(=O)c1ccc(-c2ccc(Br)cc2)o1>>O=C(O)CCC(O)c1ccc(-c2ccc(Br)cc2)o1,,C1COCCO1,O,[BH4-].[Na+],,test
US03952013,CC(C)CCBr.CCOC(=O)c1cc(=O)c2cc(O)ccc2s1>>CCOC(=O)c1cc(=O)c2cc(OCCC(C)C)ccc2s1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160016968A1,NC(=NO)c1cc(OCC2CC2)c(C2CC2)cn1.O=C(O)C1CC1>>c1c(-c2noc(C3CC3)n2)ncc(C2CC2)c1OCC1CC1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20140296208A1,COCCOCCOCCOc1cc(N)cc(OC(F)F)c1.COc1c(NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)cc(C(C)(C)C)cc1NS(C)(=O)=O>>COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)cc(NS(C)(=O)=O)c4OC)c4ccccc34)n2)cc(OC(F)F)c1,,CN(C)C=O,,,,test
US20150119362A1,CCc1c(C)nc(-c2ccc(Cl)s2)nc1Nc1ccc(CC(=N)NO)cc1.O=C(Cl)Oc1ccccc1>>CCc1c(C)nc(-c2ccc(Cl)s2)nc1Nc1ccc(C/C(=N\C(=O)Oc2ccccc2)NO)cc1,,ClCCl,,CCN(CC)CC,,test
US20110190280A1,COC(=O)c1cccc(N(C)C)c1.Cc1ccnc(Cl)n1>>CN(C)c1cccc(C(=O)Cc2ccnc(Cl)n2)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20100305131A1,CCOC(=O)C[C@@H](Cc1ccc(Br)cc1)NC(=O)OC(C)(C)C.OB(O)c1cccc(Cl)c1>>CCOC(=O)C[C@@H](Cc1ccc(-c2cccc(Cl)c2)cc1)NC(=O)OC(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20140309245A1,CC(C)(C)OC(=O)N1CC(NC(=O)OCC[Si](C)(C)C)C(C(=O)Nc2cccc(F)c2)C1>>CC(C)(C)OC(=O)N1CC(N)C(C(=O)Nc2cccc(F)c2)C1,,CCOCC,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20090281311A1,Brc1cccnc1.CC(C)(C)c1ccc(-c2nc(-c3ccc(-c4ccc(Br)cc4)cc3)nc(-c3ccc(C(C)(C)C)cc3)n2)cc1>>CC(C)(C)c1ccc(-c2nc(-c3ccc(-c4ccc(-c5cccnc5)cc4)cc3)nc(-c3ccc(C(C)(C)C)cc3)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20070167443A1,Cc1ccc(C(=O)c2n[nH]c3ccccc3c2=O)cc1C.Cc1cccc(CBr)n1>>Cc1cccc(Cn2nc(C(=O)c3ccc(C)c(C)c3)c(=O)c3ccccc32)n1,,CN(C)C=O,,[H-].[Na+],,test
US20020062029A1,COC(=O)c1ccc(C[NH3+])cc1[N+](=O)[O-].CS(=O)(=O)Cl>>COC(=O)c1ccc(CNS(C)(=O)=O)cc1[N+](=O)[O-],,ClCCl,,CCN(CC)CC,,test
US20150203505A1,CNC(=O)c1[nH]c2c(Br)cc3c(c2c1CCNC(=O)OC(C)(C)C)CCO3>>CNC(=O)c1[nH]c2ccc3c(c2c1CCNC(=O)OC(C)(C)C)CCO3,[Pd],CCO,,C1CCOC1,CCN(CC)CC,test
US20140375943A1,BrCCCOCc1ccccc1.O=C(O)c1ccc(-c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)cc1>>O=C(OCCCOCc1ccccc1)c1ccc(-c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040048858A1,CC(=O)c1ccc(C(=O)O)cc1.O=Cc1ccc(N2CCCC2)c(-c2cccs2)c1>>O=C(O)c1ccc(C(=O)/C=C/c2ccc(N3CCCC3)c(-c3cccs3)c2)cc1,,CN(C)C=O,O,[Na+].[OH-],,test
US04282246,COc1ccc(S)cc1.O=C(O)c1coc(Br)c1>>COc1ccc(Sc2cc(C(=O)O)co2)cc1,,CN(C)C=O,,,,test
US20040186301A1,CCOC(=O)C(CCCSC(c1ccccc1)(c1ccccc1)c1ccccc1)CC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)CC(CCCSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O,,CO,O,[Na+].[OH-],,test
US20080119488A1,CCN(CC)CCCO.Cc1ccc(Cn2c(-c3ccc(Oc4ccc(N)cc4)cc3)cccc2=O)c(C)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCN(CC)CCCOC(=O)Nc1ccc(Oc2ccc(-c3cccc(=O)n3Cc3ccc(C)cc3C)cc2)cc1,,ClCCl,,,,test
US20050009871A1,CC(C)Oc1ccc(N)cc1.O=[N+]([O-])c1ccc(Oc2c(Cl)cc(S(=O)(=O)Cl)cc2Cl)c(Cl)c1>>CC(C)Oc1ccc(NS(=O)(=O)c2cc(Cl)c(Oc3ccc([N+](=O)[O-])cc3Cl)c(Cl)c2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110166021A1,CCC=C(Br)Br.Oc1cccc(F)c1F>>Fc1cccc(OC/C=C/CBr)c1F,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04460777,CCC(=O)c1cccnc1.CCO.NNc1ccc(CCC(=O)O)cc1>>CCOC(=O)CCc1ccc2[nH]c(-c3cccnc3)c(C)c2c1,,O,,Cl,[Na+].[OH-],test
US20120157427A1,O=[N+]([O-])O.c1cc(C2CC2)n[nH]1>>O=[N+]([O-])c1c[nH]nc1C1CC1,,O=S(=O)(O)O,,,,test
US06365603B1,Cc1ccc(S(=O)(=O)OCC2CCC2)cc1.O=Cc1cc(Cl)ccc1O>>O=Cc1cc(Cl)ccc1OCC1CCC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160251308A1,CC(=O)OC(C)=O.COC1=C(OC)[C@@H](O)[C@@H](C/C=C(\C)CC/C=C(\C)CCC=C(C)C)[C@H](C)C1=O>>COC1=C(OC)C(OC(C)=O)C(C/C=C(\C)CC/C=C(\C)CCC=C(C)C)C(C)C1=O,,CCOC(C)=O,c1ccncc1,,,test
US20160102104A1,CS(=O)(=O)Cl.O=[N+]([O-])c1ccccc1OCCOCCOCCO>>CS(=O)(=O)OCCOCCOCCOc1ccccc1[N+](=O)[O-],,ClCCl,,CCN(CC)CC,Cl,test
US20110306606A1,CC(C)c1nc(-c2ccc(N)cc2)cs1.O=[N+]([O-])c1ccc(Cl)nc1Cl>>CC(C)c1nc(-c2ccc(Nc3nc(Cl)ccc3[N+](=O)[O-])cc2)cs1,,CO,,CCN(CC)CC,,test
US04220761,C#CCBr.CCOC(=O)C(=NO)C(C)=O>>C#CCON=C(C(C)=O)C(=O)OCC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110312931A1,CI.Oc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>COc1cc(C(F)(F)F)cc(C(F)(F)F)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20060258721A1,CN1CC=C(c2c[nH]c3ccc(N)cc23)C(F)C1.CSC(=N)c1cccs1>>CN1CC=C(c2c[nH]c3ccc(NC(=N)c4cccs4)cc23)C(F)C1,,CCO,,I,,test
US04065617,Cl.FC(F)(F)CN1N=C2C(=Cc3ccccc3)CNCC2C1c1ccccc1.N#CN>>Cl.N=C(N)N1CC(=Cc2ccccc2)C2=NN(CC(F)(F)F)C(c3ccccc3)C2C1,,CCO,,,,test
US20090018156A1,CCn1cc(-c2ccnc3c2ccn3S(=O)(=O)c2ccc(C)cc2)c(-c2cccc([N+](=O)[O-])c2)n1>>CCn1cc(-c2ccnc3[nH]ccc23)c(-c2cccc(N)c2)n1,,CO,,[Na+].[OH-],,test
US20060148858A1,CC(C)(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO.COC(=O)Cc1cccc(OC)c1O>>COc1cccc(CC(=O)O)c1OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1C(C)(C)C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US05578627,Cl.NC(COc1noc2ccc(Cl)cc12)c1cccc(O)c1>>Cl.NC(COc1noc2ccc(Cl)cc12)c1cccc(O)c1,,CCO,,CC(C)O,,test
US20020072616A1,CCOC(=O)/C=C(\C)c1cccc(C#N)c1>>C/C(=C\C(=O)O)c1cccc(C#N)c1,,C1CCOC1,O,CO,[Li+].[OH-],test
US20040063735A1,COC(=O)C(=Cc1ccc2c(ccn2S(=O)(=O)CC[Si](C)(C)C)c1)NC(=O)OCc1ccccc1>>COC(=O)C(N)Cc1ccc2c(ccn2S(=O)(=O)CC[Si](C)(C)C)c1,[Pd],CO,,,,test
US04882085,CCCCCCCCCCCCI.CCOC(=O)[C@H](C)O>>CCCCCCCCCCCCOC(C)C(=O)OCC,,CCOCC,,,,test
US20080312226A1,O=C=Nc1cccc(F)c1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>O=C(Nc1cccc(F)c1)N1CCN(c2nc(-c3ccccc3)ns2)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20050107395A1,COc1ccccc1N1CCN(C(=O)[C@H](N)Cc2ccncc2)CC1>>COc1ccccc1N1CCN(C[C@H](N)Cc2ccncc2)CC1,,C1CCOC1,O,B,Cl,test
US20120058984A1,COC(=O)Cl.Nc1ccc2nc(Nc3cc(Cc4ccccc4)nc(N[C@@H]4CC[C@@H](O)CC4)n3)sc2c1>>COC(=O)Nc1ccc2nc(Nc3cc(Cc4ccccc4)nc(N[C@@H]4CC[C@@H](O)CC4)n3)sc2c1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20140205537A1,CN(C)S(=O)(=O)n1cncc1C1=CCOCC1>>CN(C)S(=O)(=O)n1cncc1C1CCOCC1,[Pd],CCO,,,,test
US04113858,O=C(N[C@@H](Cc1ccccc1)C(=O)O)OCc1ccccc1>>N[C@@H](Cc1ccccc1)C(=O)O,,ClCCl,,,,test
US20100016319A1,CC(C)(C)c1cc(NC(=O)NCc2ccccc2O)n(-c2cccnc2)n1.Clc1ccnc(Cl)n1>>CC(C)(C)c1cc(NC(=O)NCc2ccccc2Oc2ccnc(Cl)n2)n(-c2cccnc2)n1,,CC(C)=O,,[Na+].[OH-],,test
US20030069284A1,COc1cc(CC(OC(Cc2ccc([N+](=O)[O-])c(OC)c2)c2ccccc2)c2ccccc2)ccc1[N+](=O)[O-]>>COc1cc(COCc2ccccc2)ccc1N,[Zn],CO,,C,O=C[O-].[NH4+],test
US20010034343A1,COC(=O)c1cc(N)ccc1OC.S=C(Oc1ccccn1)Oc1ccccn1>>COC(=O)c1cc(N=C=S)ccc1OC,,ClCCl,,,,test
US20160168100A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C1NCCc2cc(OCc3ccccc3)c(OC)cc21>>CCOC(=O)C1c2cc(OC)c(OCc3ccccc3)cc2CCN1C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US04731105,CC(C)SC(F)(F)c1nnc(N)s1.Cl>>CC(C)SC(F)(F)c1nnc(Cl)s1,,CC(=O)O,O,O=N[O-].[Na+],,test
US20120142667A1,COC(=O)COc1cccc([N+](=O)[O-])c1C>>COC(=O)COc1cccc(N)c1C,[Pd],C1CCOC1,,CO,,test
US20130317001A1,COC(=O)C1CCC2CC2C1>>OCC1CCC2CC2C1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140228360A1,BrCC1CO1.c1ccc2c(c1)CNC2>>c1ccc2c(c1)CN(CC1CO1)C2,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04304728,CCOC(=O)C1=CC(=O)C2(C(=O)c3ccccc3)OC2O1.Cl>>O=C(O)c1cc(=O)c(Cl)c(-c2ccccc2)o1,,C1COCCO1,,,,test
US20060276475A1,CC(C)(C)OC(=O)N1CCC[C@@H]1CN.CS(=O)(=O)c1nc(N)n2nc(-c3ccco3)nc2n1>>CC(C)(C)OC(=O)N1CCCC1CNc1nc(N)n2nc(-c3ccco3)nc2n1,,CC#N,,,,test
US20070167472A1,COC(=O)C(C(=O)OC)c1ccc(Br)cc1.N=CN>>Oc1ncnc(O)c1-c1ccc(Br)cc1,,CO,,Cl,[Na],test
US20100311966A1,CCc1[nH]c(C(OC)OC)nc1C(F)(F)F>>CCc1[nH]c(C=O)nc1C(F)(F)F,,O=S(=O)(O)O,,,,test
US05204462,CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)O.Cc1cccc(N)c1C(=O)O>>CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)Nc1cccc(C)c1C(=O)O,,C1CCOC1,CN(C)C=O,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20100216746A1,N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CN)c2F)c1.O=C(O)c1ccno1>>N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CNC(=O)c3ccno3)c2F)c1,,CN(C)C=O,CO,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US03939196,COc1ccc(C2CC(F)(F)C2(Cl)Cl)cc1>>COc1ccc(C2=C(Cl)C(F)(F)C2)cc1,,CCO,,[K+].[OH-],,test
US20110201593A1,CCN1CC[C@@H](N)[C@@H](F)C1.O=[N+]([O-])c1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1Cl>>CCN1CC[C@@H](Nc2c([N+](=O)[O-])cnc3c2ccn3S(=O)(=O)c2ccccc2)[C@@H](F)C1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US05490872,COCCCNc1cccc2ccccc12.COc1ccccc1N.O=N[O-]>>COCCCNc1ccc(N=Nc2ccccc2OC)c2ccccc12,,Cc1ccccc1C,,Cl,,test
US20060276496A1,COC(=O)c1ccc2c(c1)c(C1(C#N)CCC1)cn2C(=O)OC(C)(C)C>>COC(=O)c1ccc2[nH]cc(C3(C#N)CCC3)c2c1,,O=C(O)C(F)(F)F,,,,test
US20120214803A1,NS(N)(=O)=O.Nc1c(C=O)ccc2cccnc12>>O=S1(=O)N=Cc2ccc3cccnc3c2N1,,c1ccncc1,,,,test
US04976773,COc1ccc(O)cc1.Clc1ccc(Br)cc1>>COc1ccc(Oc2ccc(Cl)cc2)cc1,[Cu],,,[K+].[OH-],,test
US05208243,NC(=O)C1CCN(CCCOc2ccc(F)cc2)CC1>>NCC1CCN(CCCOc2ccc(F)cc2)CC1,,O,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110015174A1,CCCCCCCCc1ccc(N=C=O)cc1.CCOC(=O)CC1(N)CCN(C(=O)OCc2ccccc2)C1>>CCCCCCCCc1ccc(NC(=O)NC2(CC(=O)OCC)CCN(C(=O)OCc3ccccc3)C2)cc1,,ClCCl,,CCN(CC)CC,,test
US20120302641A1,Cc1cc(Cl)ccc1-c1ccc(N)cc1Cl.FC(F)(F)c1ccc(CBr)c(Br)c1>>Cc1cc(Cl)ccc1-c1ccc(NCc2ccc(C(F)(F)F)cc2Br)cc1Cl,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04416884,C1CNCCN1.COc1ccccc1S(=O)(=O)Oc1ccc2c(=O)c(C(=O)O)cn3c2c1CCC3C>>CC1CCc2c(N3CCNCC3)ccc3c(=O)c(C(=O)O)cn1c23,,CS(C)=O,,,,test
US06110962,O=C1CCO1.Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br>>CC(Oc1c(Br)cc(-c2c3ccccc3c(Br)c3sc4ccccc4c23)cc1Br)C(=O)O,,C1CCOC1,O,Cl,CC(C)(C)[O-].[K+],test
US20080119539A1,CCCCCC(OCc1ccc(OC)cc1)c1ccc(NC(C)=O)cc1.COC(=O)CCCC#CCI>>CCCCCC(OCc1ccc(OC)cc1)c1ccc(N(CC#CCCCC(=O)OC)C(C)=O)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US05242912,CI.O=C(O)c1cc([N+](=O)[O-])cc2c1NCCCC2>>COC(=O)c1cc([N+](=O)[O-])cc2c1NCCCC2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140323537A1,CC(C)I.Oc1c(Cl)cc(I)cc1Cl>>CC(C)Oc1c(Cl)cc(I)cc1Cl,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20160002175A1,NC1CCC1.Nc1nc(Cl)cc(Cl)n1>>Nc1nc(Cl)cc(NC2CCC2)n1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20160152621A1,CC(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)Nc1ccc(-c2cnco2)c(N(C)C)c1>>CC(C)C[C@@H](N)C(=O)Nc1ccc(-c2cnco2)c(N(C)C)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US03993646,COC(=O)C1N2C(=O)C(NC(=O)COc3ccccc3)[C@H]2SCC1(C)I>>COC(=O)C1=C(C)CS[C@@H]2C(NC(=O)COc3ccccc3)C(=O)N12,,CC#N,,CC(=O)[O-].[Na+],,test
US20060074075A1,CC(=O)Cl.O=[N+]([O-])c1ccc2c(c1)NCCCC2>>CC(=O)N1CCCCc2ccc([N+](=O)[O-])cc21,,ClCCl,,O=C([O-])O.[Na+],,test
US20150094296A1,CCOC(=O)C(C)(C)n1cc(Nc2nccc(=O)[nH]2)cn1.O=P(Cl)(Cl)Cl>>CCOC(=O)C(C)(C)n1cc(Nc2nccc(Cl)n2)cn1,,CC#N,,[Na+].[OH-],,test
US20020111353A1,N#CN.Nc1ccc(S(N)(=O)=O)cc1>>N=C(N)Nc1ccc(S(N)(=O)=O)cc1,,CCOCC,O,C1COCCO1,Cl,test
US20140275173A1,O=CCCC12CCC(c3cccc(Oc4ccccc4)c3)(CC1)CO2>>OCCCC12CCC(c3cccc(Oc4ccccc4)c3)(CC1)CO2,,Cc1ccccc1,ClCCl,CC(C)C[AlH]CC(C)C,,test
US20090047244A1,C=CCCCCN(C)C(=O)C(F)(F)F.Cc1ccc(S(=O)(=O)O)cc1>>C=CCCCCNC.Cc1ccc(S(=O)(=O)O)cc1,,CO,,,,test
US20050119256A1,COC(=O)[C@H](Cc1cc(Cl)c(O)c(Cl)c1)NC(=O)C(F)(F)F.OCc1cccc2nc(-c3ccccc3)oc12>>COC(=O)[C@H](Cc1cc(Cl)c(OCc2cccc3nc(-c4ccccc4)oc23)c(Cl)c1)NC(=O)C(F)(F)F,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04918080,Cn1ccc2c(C(=O)O)cccc21.[Li]C>>CC(=O)c1cccc2c1ccn2C,,C1CCOC1,,,,test
US20150065507A1,Cc1cc(C(C)C)cnc1N.O=S(=O)(Cl)c1ccc(F)cc1>>Cc1cc(C(C)C)cnc1NS(=O)(=O)c1ccc(F)cc1,,c1ccncc1,,,,test
US20160108041A1,Cn1c(Nc2ccc(I)cc2F)c(C(=O)NOCCO[Si](C)(C)C(C)(C)C)c2c(c1=O)CCC2>>Cn1c(Nc2ccc(I)cc2F)c(C(=O)NOCCO)c2c(c1=O)CCC2,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150353559A1,CC(C)(C)OC(=O)N1C[C@@H]2CNC[C@@H]2C1.O=C(O)CCc1cc(Cl)cc(Cl)c1>>CC(C)(C)OC(=O)N1C[C@@H]2CN(C(=O)CCc3cc(Cl)cc(Cl)c3)C[C@@H]2C1,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120035122A1,FC(F)(F)C1(c2cc(Cl)c(Cl)c(Cl)c2)CC(c2ccc(I)c(Br)c2)=NO1.O=C1CN(C(c2ccccc2)c2ccccc2)C1>>OC1(c2ccc(C3=NOC(c4cc(Cl)c(Cl)c(Cl)c4)(C(F)(F)F)C3)cc2Br)CN(C(c2ccccc2)c2ccccc2)C1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20100234365A1,CCOC(=O)CN1CC(c2cccc(C(F)(F)F)c2)N(c2ccc(Oc3ccc(Cl)cc3)cc2)C1=O>>O=C(O)CN1CC(c2cccc(C(F)(F)F)c2)N(c2ccc(Oc3ccc(Cl)cc3)cc2)C1=O,,CCO,,[Na+].[OH-],,test
US06130239,C#CCCCC(=O)OC.COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(Br)c21>>COC(=O)CCCC#Cc1cccc2c1/C(=C/c1[nH]ccc1OC)C(=O)N2,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCN(CC)CC,CN(C)C=O,,,test
US20110014186A1,CC(C)(C)[Si](C)(C)NS(=O)(=O)c1cc(C(=O)c2ccc3c(Br)cn([Si](C)(C)C(C)(C)C)c3c2)ccc1Cl.OB(O)c1ccccc1>>NS(=O)(=O)c1cc(C(=O)c2ccc3c(-c4ccccc4)c[nH]c3c2)ccc1Cl,,COCCOC,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20060100218A1,COc1ccc(B(O)O)cc1OC.O=S(=O)(c1ccccc1)n1cc(Br)c2cccnc21>>COc1ccc(-c2c[nH]c3ncccc23)cc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US06107301,CCN(c1nc(C)cc(C)n1)c1ccc(C(C)C)cc1SC.O>>CCN(c1nc(C)cc(C)n1)c1ccc(C(C)C)cc1S(C)=O,,O,,CO,,test
US20150037280A1,NC(=O)c1cc(Cl)ccn1.Nc1ccc(O)c(F)c1F>>NC(=O)c1cc(Oc2ccc(N)c(F)c2F)ccn1,,CN(C)C=O,O,CC(C)(C)[O-].[K+],,test
US20110224188A1,O=C(NC1(C(=O)NC2(c3cc(CN4CCCC4)ccn3)CC2)CC1)OCc1ccccc1>>NC1(C(=O)NC2(c3cc(CN4CCCC4)ccn3)CC2)CC1,[Pd],CO,,,,test
US20140323475A1,CS(N)(=O)=O.O=C(O)c1cccc2c1ccn2Cc1cc(Cl)ccc1OCc1ccc(Cl)cc1F>>CS(=O)(=O)NC(=O)c1cccc2c1ccn2Cc1cc(Cl)ccc1OCc1ccc(Cl)cc1F,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US08748452B2,COCOc1cc(I)ccc1C(=O)OC.N#Cc1ccn2ccccc12>>COCOc1cc(-c2cc(C#N)c3ccccn23)ccc1C(=O)OC,,CN1CCCC1=O,,O,CC(=O)[O-].[K+],test
US06451802B1,N=CN.NNC(=O)Nc1ccc([N+](=O)[O-])cc1>>O=c1[nH]ncn1-c1ccc([N+](=O)[O-])cc1,,CCCCO,,CC(=O)O,,test
US20150376611A1,CC1(C)O[C@@H]2[C@H](O1)[C@@H](CO[Si](C)(C)C(C)(C)C)O[C@H]2n1c(Br)nc2c(/C=C/c3ccccc3)ncnc21>>OC[C@H]1O[C@@H](n2c(Br)nc3c(/C=C/c4ccccc4)ncnc32)[C@H](O)[C@@H]1O,,O,O=C(O)C(F)(F)F,,,test
US20070185155A1,BrCCCOc1ccc(-c2ccccc2)cc1.OC(c1ccccc1)(c1ccccc1)C12CCN(CC1)CC2>>OC(c1ccccc1)(c1ccccc1)C12CC[N+](CCCOc3ccc(-c4ccccc4)cc3)(CC1)CC2.[Br-],,CC#N,,,,test
US20050026944A1,CCOC(/C=C/c1cnc(N)c2c(-c3ccc(NC(=O)c4cc5ccccc5n4C)c(OC)c3)csc12)OCC>>COc1cc(-c2csc3c(/C=C/C=O)cnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C,,CC(C)=O,O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120202797A1,CCOC(=O)c1cc(Br)cn1Cc1cc(Cl)ccc1[N+](=O)[O-]>>CCOC(=O)c1cc(Br)cn1Cc1cc(Cl)ccc1N,[Fe],CC(=O)O,,,,test
US05686482,COC(=O)c1cc(C#N)c(OC)cc1OC>>COc1cc(OC)c(C(=O)O)cc1C#N,,CC#N,O,Cl,[Na+].[OH-],test
US20110152287A1,COc1ccc(NC(=O)c2ccc3nc(N4CCN(C(=O)[C@H](Cc5cccs5)NC(=O)OC(C)(C)C)CC4)sc3c2)cc1OC.Cl>>COc1ccc(NC(=O)c2ccc3nc(N4CCN(C(=O)[C@@H](N)Cc5cccs5)CC4)sc3c2)cc1OC.Cl,,C1COCCO1,,,,test
US20030171411A1,Nc1nccs1.O=C(O)C(SCc1ccco1)c1ccc(Cl)c(Cl)c1>>O=C(Nc1nccs1)C(SCc1ccco1)c1ccc(Cl)c(Cl)c1,,C1CCOC1,,,,test
US20120083469A1,CC(=O)NC(CCCN)(CCCCB1OC(C)(C)C(C)(C)O1)C(=O)NC(C)(C)C.O=CCc1ccc(Cl)cc1Cl>>CC(=O)NC(CCCCB1OC(C)(C)C(C)(C)O1)(CCCNCCc1ccc(Cl)cc1Cl)C(=O)NC(C)(C)C,,ClCCl,,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20110059934A1,Cc1ccc(N)nc1.O=Cc1ccc(F)cc1.[C-]#[N+]C(C)(C)C>>Cc1ccc2nc(-c3ccc(F)cc3)c(N)n2c1,,CO,,,,test
US20050054681A1,CC(=O)c1cc(Br)cc(Br)c1O.CCOC(=O)OCC>>O=c1cc(O)c2cc(Br)cc(Br)c2o1,,Cc1ccccc1,,[Na+].[OH-],,test
US20040260088A1,COc1ccc(O)cc1C=O.N#Cc1ccc(Cl)cc1F>>COc1ccc(Oc2cc(Cl)ccc2C#N)cc1C=O,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100234351A1,COC(=O)C1=Cc2c(ncnc2Nc2cnc(Oc3cccc(OC(F)(F)F)c3)c(Cl)c2)NCC1>>O=C(O)C1=Cc2c(ncnc2Nc2cnc(Oc3cccc(OC(F)(F)F)c3)c(Cl)c2)NCC1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US04342777,CC(=O)O.COc1ccc(C(C)O)cc1.Oc1ccc2c(c1)OCO2>>COc1ccc(C(C)c2cc3c(cc2OC)OCO3)cc1,,CC(=O)O,O,O=C(O)C(=O)O,,test
US04416826,CC(C)(C)OOC(=O)c1ccc(C(=O)c2ccccc2)cc1.COc1ccc(C(=O)c2ccc(C(=O)O)cc2)cc1>>COc1ccc(C(=O)c2ccc(C(=O)OOC(C)(C)C)cc2)cc1,,CCOCC,ClCCl,,,test
US20090326004A1,CCOC(=O)C(O)c1cccs1>>O=C(O)C(O)c1cccs1,,CO,O,Cl,[K+].[OH-],test
US20130345258A1,COc1cc2nccc(Cl)c2cc1S(=O)(=O)C(C)(C)C.Nc1n[nH]c2ncc(F)cc12>>COc1cc2nccc(Nc3n[nH]c4ncc(F)cc34)c2cc1S(=O)(=O)C(C)(C)C,Cl,CO,,CCO,,test
US20090042929A1,NCc1ccco1.O=C(O)c1ccc(OCC(=O)C23CC4CC(CC(C4)C2)C3)cc1>>O=C(NCc1ccco1)c1ccc(OCC(=O)C23CC4CC(CC(C4)C2)C3)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US20160120850A1,CC(=O)c1ccc(Br)c2ccccc12.CC1(C)COCCN1>>CC(c1ccc(Br)c2ccccc12)N1CCOCC1(C)C,CC(=O)O,ClCCl,,O=C([O-])O.[Na+],,test
US04127585,COC(=O)C1=C(O)c2ccsc2S(=O)(=O)C1.Cc1cc(N)no1>>Cc1cc(NC(=O)C2=C(O)c3ccsc3S(=O)(=O)C2)no1,,Cc1ccccc1C,,,,test
US20100111888A1,CCCCCC(CCC1(C)OCCO1)C(C)=O>>CCCCCC(CCC(C)=O)C(C)=O,,C1CCOC1,,Cl,O,test
US20120289526A1,CC(C)c1cccc(Oc2ncc(NC(=O)[C@@H](C)N)cn2)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)c1cccc(Oc2ncc(N3C(=O)N[C@H](C)C3=O)cn2)c1,,ClCCl,,CCN(CC)CC,O,test
US20080051415A1,CC(C)(C)OC(=O)N1CCN(c2nc3ncccc3o2)C(COc2cccnc2)C1.Cl>>Cl.c1cncc(OCC2CNCCN2c2nc3ncccc3o2)c1,,CO,,C1COCCO1,,test
US20160074528A1,CC(S)CN.O=[N+]([O-])c1ccc(SSc2ccc([N+](=O)[O-])cn2)nc1>>CC(CN)SSc1ccc([N+](=O)[O-])cn1,O=[Mn]=O,ClCCl,,Cl,,test
US20050288367A1,COC(=O)CCOc1ccc(OCc2cccc(F)c2)cc1>>O=C(O)CCOc1ccc(OCc2cccc(F)c2)cc1,,C1CCOC1,Cl,,,test
US06002008,C#Cc1cccc(Nc2c(C#N)cnc3ccc(N)cc23)c1.C=CC(=O)Cl>>C#Cc1cccc(Nc2c(C#N)cnc3ccc(NC(=O)C=C)cc23)c1,,CN(C)C=O,,C1CCOC1,CCN(CC)CC,test
US20130137691A1,COC(=O)C(C)(C)P(=O)=O.O=C1CCC(c2ccc(O)cc2)CC1>>COC(=O)C=C1CCC(c2ccc(O)cc2)CC1,,C1CCOC1,,[H-].[Na+],,test
US20040192688A1,ClCCCBr.Oc1ccc2ccccc2c1>>ClCCCOc1ccc2ccccc2c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140148433A1,COC(=O)CN(C(=O)OC)c1c(N)nc(-c2nn(Cc3ccccc3F)c3ncccc23)nc1N>>COC(=O)N1CC(=O)Nc2nc(-c3nn(Cc4ccccc4F)c4ncccc34)nc(N)c21,,CCO,O,Cl,[Li+].[OH-],test
US20050187236A1,CCNC(=O)n1ccc2cc(Oc3ccnc(N(C(=O)Oc4ccccc4)C(=O)Oc4ccccc4)c3)ccc21.COC(=O)CN>>CCNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)NCC(=O)O)c3)ccc21,,CCN(CC)CC,,CN(C)C=O,Cl,test
US04910212,COc1ccc([C@@H]2CCc3cc(OC)ccc3[C@@H]2CS(=O)(=O)OC)cc1.Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>COc1ccc([C@@H]2CCc3cc(OC)ccc3[C@@H]2Cn2cncc2C)cc1,,CC#N,,,,test
US20140249129A1,COCCO.N#Cc1ccc(C2C3=C(CCCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C(=O)Oc2ccc([N+](=O)[O-])cc2)cc1>>COCCOC(=O)N1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CCC2)C1c1ccc(C#N)cc1,,C1CCOC1,,O,[H-].[Na+],test
US20080045525A1,C1CCNCC1.CCOC(=O)c1cnc(N2CCN(c3cc(Cl)nc(N4CCCC4C)n3)[C@H](C)C2)c(C)c1>>CCOC(=O)c1cnc(N2CCN(c3cc(N4CCCCC4)nc(N4CCCC4C)n3)[C@H](C)C2)c(C)c1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,,test
US20040209905A1,CCC(O)N1CCCCC1.CCNC(=O)Nc1ccc(Oc2ncnc3cc(O)c(OC)cc23)cc1Cl>>CCNC(=O)Nc1ccc(Oc2ncnc3cc(OCCCN4CCCCC4)c(OC)cc23)cc1Cl,,CN(C)C=O,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06300353B1,C[C@@H](C(N)=S)[C@](O)(Cn1cncn1)c1cc(F)ccc1F.N#Cc1ccc(C(=O)CBr)cc1>>C[C@@H](c1nc(-c2ccc(C#N)cc2)cs1)[C@](O)(Cn1cncn1)c1cc(F)ccc1F,,CCO,,,,test
US20020147365A1,CCCCCCCCCCCCN.COc1cccc(CN=C=S)c1>>CCCCCCCCCCCCNC(=S)NCc1cccc(OC)c1,,CCO,,,,test
US05506219,CCC(=O)CC(=O)OC.O=Cc1ccc(F)cc1>>CCC(=O)C(=Cc1ccc(F)cc1)C(=O)OC,CC(=O)O,CCOCC,c1ccccc1,C1CCNCC1,,test
US04874775,ClCc1cncnc1.Nc1ccc(F)cc1F>>Fc1ccc(NCc2cncnc2)c(F)c1,,ClCCl,O,CN(C)C=O,O=C([O-])O.[Na+],test
US05594023,BrCC1CCCCC1.C1CCOC1.CCOCC.O=C1Nc2ccc(Cl)cc2C1=O.[Mg]>>Br[Mg]CC1CCCCC1.O=C1Nc2ccc(Cl)cc2C1(O)CC1CCCCC1,,C1CCOC1,CCOCC,[Cl-].[NH4+],,test
US20140031364A1,Fc1ccccc1N1CCNCC1.Nc1onc(-c2ccc(OC(F)(F)F)cc2)c1C(=O)O>>Nc1onc(-c2ccc(OC(F)(F)F)cc2)c1C(=O)N1CCN(c2ccccc2F)CC1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20060089371A1,COC(=O)[C@H](Cc1ccccc1)Nc1cc(-c2ccc(C#Cc3ccccc3)cc2)ncn1>>O=C(O)[C@H](Cc1ccccc1)Nc1cc(-c2ccc(C#Cc3ccccc3)cc2)ncn1,,CO,,[Na+].[OH-],,test
US20010003782A1,C[C@H](CCC(=O)O)[C@H]1CC=C2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@@H]1CC3.ClCc1ccccc1>>C[C@H](CCC(=O)OCc1ccccc1)[C@H]1CC=C2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@@H]1CC3,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040023990A1,CCCc1nn(C)c2c(Cl)nc(CCC(=O)OC)nc12.COc1ccc(CN)cc1Cl>>CCCc1nn(C)c2c(NCc3ccc(OC)c(Cl)c3)nc(CCC(=O)OC)nc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05120745,CC(C)(C)c1n[nH]c(SCC2OCCO2)n1.CN(C)C(=O)Cl>>CN(C)C(=O)n1ccnn1,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20120119198A1,CC(=O)ON(CCOCCO)C(=O)OC(C)(C)CCc1ccccc1.CI>>COCCOCCN(OC(C)=O)C(=O)OC(C)(C)CCc1ccccc1,,O,,C1CCOC1,[H-].[Na+],test
US04507498,CCCc1c(O)ccc(C(C)=O)c1O.CCCc1c(OCC(=O)OCC)ccc(C(C)=O)c1OCCCCOCCCCI>>CCCc1c(OCCCCOCCCCOc2c(C(C)=O)ccc(OCC(=O)OCC)c2CCC)ccc(C(C)=O)c1O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06214873B1,BrCCc1ccccc1.CCOC(=O)C(NC(C)=O)C(=O)OCC>>CCOC(=O)C(CCc1ccccc1)(NC(C)=O)C(=O)OCC,,CN(C)C=O,,[H-].[Na+],,test
US20100184758A1,CC(C)(C)OC(=O)N1C(c2nc(-c3ccc(F)cc3)cn2C(=O)OC(C)(C)C)Cc2c(n(C(=O)OC(C)(C)C)c3ccc(Br)cc23)C1C1CCOCC1.c1cn[nH]c1>>CC(C)(C)OC(=O)N1C(c2nc(-c3ccc(F)cc3)c[nH]2)Cc2c([nH]c3ccc(-n4cccn4)cc23)C1C1CCOCC1,I[Cu]I,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20160096827A1,Cc1cn[nH]c1C(=O)O.N#Cc1cc(-c2ncnc(Nc3ccc(N4CCN(C5COC5)CC4)cc3)n2)cc(F)c1O[C@H]1CCNC[C@H]1F>>Cc1cn[nH]c1C(=O)N1CC[C@H](Oc2ccc(-c3ncnc(Nc4ccc(N5CCN(C6COC6)CC5)cc4)n3)cc2C#N)[C@H](F)C1,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US04810699,O=[N+]([O-])c1c(C=CN2CCCC2)cccc1OCc1ccccc1>>c1ccc(COc2cccc3cc[nH]c23)cc1,[Ni],CO,,NN,O,test
US06818644B1,COc1ccc(-c2ccccc2)cc1.c1ccc(CN2CCNCC2)cc1>>c1ccc(CN2CCN(c3ccc(-c4ccccc4)cc3)CC2)cc1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US03991201,CS(=O)(=O)OCC(c1ccc(Cl)cc1Cl)C1CCCC1.c1c[nH]cn1>>Clc1ccc(C(Cn2ccnc2)C2CCCC2)c(Cl)c1,,CN(C)C=O,,,,test
US20050261358A1,CN(C)C1(c2ccccc2)CCC(N)CC1.O=C(NCCc1c[nH]c2ccccc12)Oc1ccccc1>>CN(C)C1(c2ccccc2)CCC(NC(=O)NCCc2c[nH]c3ccccc23)CC1,,C1COCCO1,,,,test
US20080108667A1,O=S(Cl)Cl.OCc1cnc(Cl)c(Br)c1>>ClCc1cnc(Cl)c(Br)c1,,ClCCl,,,,test
US20160254098A1,CCCCCCCC(=O)[O-].CCCC[n+]1ccn(C)c1>>CCCCCCCC(=O)[O-].CCCC[n+]1ccn(C)c1,,O,,[Cl-].[Na+],,test
US20060148858A1,CC(C)c1nn(-c2ncccc2C(F)(F)F)cc1CCCO.COC(=O)Cc1cccc(OC)c1O>>COC(=O)Cc1cccc(OC)c1OCCCc1cn(-c2ncccc2C(F)(F)F)nc1C(C)C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20100152445A1,CCOC(=O)C1CCN(c2ccc(NC(=O)c3nc(-c4ccccc4)oc3C(F)(F)F)cc2)CC1>>O=C(Nc1ccc(N2CCC(C(=O)O)CC2)cc1)c1nc(-c2ccccc2)oc1C(F)(F)F,,CO,,[Na+].[OH-],,test
US20070167377A1,CN(C)N.COC(=O)c1ccc(CC(=O)C(F)(F)F)cc1>>COC(=O)c1ccc(CC(=NN(C)C)C(F)(F)F)cc1,,CCO,,CC(=O)O,,test
US20050070441A1,CCN=C=O.COc1ccc([N+](=O)[O-])c(Oc2cc(C)[nH]n2)n1>>CCNC(=O)n1nc(Oc2nc(OC)ccc2[N+](=O)[O-])cc1C,,CCOC(C)=O,,CCN(CC)CC,Cl,test
US20090325993A1,CC(C)(C)OC(=O)N1CCCC2(C1)N=C(c1ccc(Cl)cc1)C(=O)N2CC(=O)Nc1ccc(F)c(F)c1>>O=C(CN1C(=O)C(c2ccc(Cl)cc2)=NC12CCCNC2)Nc1ccc(F)c(F)c1,,C1COCCO1,,Cl,,test
US20160159808A1,CCOC(=O)c1cc(=O)[nH]c2cccnc12>>O=C(O)c1cc(=O)[nH]c2cccnc12,,CCO,,[Na+].[OH-],,test
US06008230,COCCO.O=C(Nc1cccc2c(Cl)ccnc12)c1c(Cl)cccc1Cl>>COCCOc1ccnc2c(NC(=O)c3c(Cl)cccc3Cl)cccc12,,CCOC(C)=O,CN1CCCC1=O,CC(C)(C)[O-].[K+],,test
US06329381B1,BrBr.Cc1ccc(Sc2nc(N)c3ncn(Cc4ccccc4)c3n2)cc1>>Cc1ccc(Sc2nc(N)c3nc(Br)n(Cc4ccccc4)c3n2)cc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20100292206A1,N.O=S(=O)(Cl)c1ccc(-c2cnco2)cc1>>NS(=O)(=O)c1ccc(-c2cnco2)cc1,,C1CCOC1,,O,,test
US20040167128A1,CCN(CC)CCCN.COC(=O)c1c(NS(=O)(=O)c2ccccc2C(=O)O)ccc2ccccc12>>CCN(CC)CCNC(=O)c1ccccc1S(=O)(=O)Nc1ccc2ccccc2c1C(=O)OC,,CN(C)C=O,O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160159773A1,COC1(c2cc(Br)nn2C)CN(C(=O)OC(C)(C)C)C1.Cl>>COC1(c2cc(Br)nn2C)CNC1.Cl,,CCOC(C)=O,,CO,,test
US06359113B1,CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)OCC1c2c(c3ccccc3c3ccccc23)-c2c1c1ccccc1c1ccccc21>>O=C(N[C@@H](Cc1ccccc1)C(=O)O)OCC1c2c(c3ccccc3c3ccccc23)-c2c1c1ccccc1c1ccccc21,,O,O=C(O)C(F)(F)F,CCOCC,,test
US05589476,NC(N)=O.Nc1cccc2c1NCCC2>>O=c1[nH]c2cccc3c2n1CCC3,,CCOCC,,O,,test
US20060100246A1,COC(=O)C1=CCCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CCC=C(CO)C1,,Cc1ccccc1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20150266824A1,Cc1cc(Cl)cc(Cl)c1.O=C=O>>Cc1cc(Cl)c(C(=O)O)c(Cl)c1,,C1CCOC1,,[Li]CCCC,,test
US20090118282A1,CC(C)(C)OC(=O)Nc1cc(CN2CCCCC2)ccc1OCCCCCSc1ccnc2cc(C(F)(F)F)ccc12>>Nc1cc(CN2CCCCC2)ccc1OCCCCCSc1ccnc2cc(C(F)(F)F)ccc12,,CO,,Cl,,test
US20130210625A1,C=Cc1cc(C)cc(C)c1C1=C(O)C2(CCN(OC)CC2)N(OC2CCCO2)C1=O.CCOC(=O)Cl>>C=Cc1cc(C)cc(C)c1C1=C(OC(=O)OCC)C2(CCN(OC)CC2)N(OC2CCCO2)C1=O,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20030087926A1,C=Cc1ccc(C(C)(C)C)cc1.CCC(=O)C(=O)[O-].Nc1cc(Cl)cc(Cl)c1>>CCOC(=O)C1CC(c2ccc(C(C)(C)C)cc2)c2c(Cl)cc(Cl)cc2N1,,CC#N,,O=C(O)C(F)(F)F,,test
US20130225529A1,COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1.ClCCl.Oc1ccccc1.On1nnc2ccccc21>>COc1ccc2c(c1)c(CC(=O)Oc1ccc(CCO)cc1)c(C)n2C(=O)c1ccc(Cl)cc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20130211075A1,CCOC(=O)C1(c2ccc(Br)cn2)CCC2(CC1)OCCO2>>O=C(O)C1(c2ccc(Br)cn2)CCC2(CC1)OCCO2,,C1CCOC1,CO,O,[Na+].[OH-],test
US20020006578A1,C=Cc1ccc(O)cc1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1ccncc1>>C=Cc1ccc(O)cc1.C=Cc1ccc(OC(=O)OC(C)(C)C)cc1,,c1ccncc1,,Cl,O,test
US20100210680A1,CC(C)(C)OC(=O)N1C[C@@H]2OCc3ccc(O)cc3[C@@H]2C1.ClCCl.O=C1CCC(=O)N1Cl>>CC(C)(C)OC(=O)N1C[C@@H]2OCc3cc(Cl)c(O)c(Cl)c3[C@@H]2C1,,C1CCOC1,,CCOC(C)=O,,test
US20070037836A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](CCNC(=O)OCc2ccccc2)CC1>>N[C@H]1CC[C@@H](CCNC(=O)OCc2ccccc2)CC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20090036688A1,C=O.FC(F)Cl.N#Cc1cc(O)n(-c2ccccc2)n1>>N#Cc1nn(-c2ccccc2)c(OC(F)F)c1CO,,[K+],[OH-],CC#N,,test
US05049664,CCCCCCCCCCCCCCC(Br)C(=O)OC.CCCCCCCCCCCCCCCCCCCC=O>>CCCCCCCCCCCCCCCCCCCC(O)C(CCCCCCCCCCCCCC)C(=O)OC,[Zn],O=S(=O)(O)O,,C[Si](C)(C)Cl,,test
US20070244103A1,COc1cnc2cccc(NC(=O)C3CCCC(CNC(=O)OC(C)(C)C)C3)c2c1>>COc1cnc2cccc(NC(=O)C3CCCC(CN)C3)c2c1,,ClCCl,,CCOCC,FB(F)F,test
US20110034464A1,CS(=O)(=O)Nc1ccc(F)cc1CN.Cl.N#CC(C(N)=O)C1OC(=O)C(Cl)=C1Cl>>CS(=O)(=O)Nc1ccc(F)cc1Cn1cc(Cl)cc(C(N)=O)c1=N.Cl,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US06495604B1,CCOC(=O)C1=CCCCC1S(=O)(=O)Nc1ccc(F)cc1F.O=C1CCC(=O)N1Br>>CCOC(=O)C1=CC(Br)CCC1S(=O)(=O)Nc1ccc(F)cc1F,CC(C)(C#N)N=NC(C)(C)C#N,Clc1ccccc1,,,,test
US20140107156A1,COCCC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc([N+](=O)[O-])c1>>COCCC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(N)c1,[Pd],CO,,N,,test
US05773467,COc1ccc(S(=O)(=O)Cl)c2cc(C(C)=O)oc12.NCc1cccnc1>>COc1ccc(S(=O)(=O)NCc2cccnc2)c2cc(C(C)=O)oc12,,ClCCl,,CCN(CC)CC,,test
US20070032485A1,CSc1ncc2c(n1)N(C)CCOC2=O.O=C(OO)c1cccc(Cl)c1>>CN1CCOC(=O)c2cnc(S(C)=O)nc21,,C1CCOC1,,,,test
US06127354,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCCc1ccccc1[N+](=O)[O-]>>CN(CCc1ccccc1[N+](=O)[O-])C(=O)OC(C)(C)C,,CCOC(C)=O,O,C1CCOC1,[Na+].[OH-],test
US20150225412A1,CC(C)C=O.N#CCC(=O)N1CCC[C@H]1Cn1c(NC(=O)c2ccc(C(F)F)s2)nc2ccccc21>>CC(C)C=C(C#N)C(=O)N1CCC[C@H]1Cn1c(NC(=O)c2ccc(C(F)F)s2)nc2ccccc21,,ClCCl,,C1CCNCC1,,test
US20140051672A1,CI.CN1C(C)(C)CC(Nc2ccc(Cl)nn2)CC1(C)C>>CN(c1ccc(Cl)nn1)C1CC(C)(C)N(C)C(C)(C)C1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US04992359,CC(=O)Oc1ccc(S(=O)(=O)Cl)cc1.OCCNCCO>>O=S(=O)(c1ccc(O)cc1)N(CCO)CCO,,ClCCl,,O,[Na+].[OH-],test
US20120202834A1,CC(C)C[Mg]Br.CON(C)C(=O)c1ccc(Cl)nc1>>CC(C)CC(=O)c1ccc(Cl)nc1,,C1CCOC1,,,,test
US04001419,COc1cccc2c(=O)c3ccc(Cl)cc3oc12.C[S-]>>COc1cccc2c(=O)c3ccc(SC)cc3oc12,,CN(C)C=O,,O,,test
US20050245529A1,C#Cc1ccc(-c2ccc(Cl)cc2)cn1.OC1CCC(c2ccc(I)cc2)C1>>OC1CCC(c2ccc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)cc2)C1,,CO,ClCCl,,,test
US20150291655A1,CCOC(=O)C1(CO)CCC(=O)CC1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)C1(COS(=O)(=O)C(F)(F)F)CCC(=O)CC1,,ClCCl,,c1ccncc1,,test
US04241064,COC(=O)c1ncc(O)c2c1[nH]c1ccccc12.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1ncc(OS(=O)(=O)c2ccc(C)cc2)c2c1[nH]c1ccccc12,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US05527819,CCOC(=N)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccccc1.N#CN>>N#CNC(=N)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccccc1,,CO,,,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(-c2ccc(O[C@H](C)[C@H](C)O)cc2)c2ccnn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(-c2ccc(O[C@H](C)[C@H](C)O)cc2)c2ccnn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US03985882,CCC1CCc2ccccc2N1.CCOC=C(C(=O)OCC)C(=O)OCC>>CCC1CCc2cccc3c(=O)c(C(=O)O)cn1c23,,[Na+],[OH-],O,,test
US05599815,O=c1ccc2ccccc2n1CCCCBr.c1ccc2c(N3CCNCC3)nsc2c1>>O=c1ccc2ccccc2n1CCCCN1CCN(c2nsc3ccccc23)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160016903A1,CCCC(=O)Cl.CN(C)C1(Cc2ccccc2)CCC2(CCNC2)CC1>>CCCCN1CCC2(CCC(Cc3ccccc3)(N(C)C)CC2)C1,,ClCCl,,CCN(CC)CC,,test
US20040067933A1,CCCCC1(CC)CN(c2ccccc2)c2cc(Br)c(OC(C)C(=O)OCC)cc2S(=O)(=O)C1>>CCCCC1(CC)CN(c2ccccc2)c2cc(Br)c(OC(C)C(=O)O)cc2S(=O)(=O)C1,,CCO,,CC(=O)O,[Na+].[OH-],test
US03991076,C1=C(N2CCCC2)CCSC1.O.O=C(CBr)c1ccc(F)cc1>>O=C(CC1CSCCC1=O)c1ccc(F)cc1,,O,,CN(C)C=O,,test
US20080015203A1,COC[C@H](C)Oc1cc(Oc2ccc(S(=O)(=O)N(C)C)cc2Cl)cc(C(=O)Nc2ccn(C)n2)c1>>COC[C@H](C)Oc1cc(Oc2ccc(S(=O)(=O)N(C)C)cc2)cc(C(=O)Nc2ccn(C)n2)c1,[Pd],C1CCOC1,CO,CCN(CC)CC,,test
US04420424,CC(C)(C)OC(=O)CC[C@@H](NC(=O)OCc1ccccc1)C(=O)O.COC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)[C@@H](N)C(C)C>>COC(=O)[C@H](Cc1ccc(OC(C)(C)C)cc1)NC(=O)[C@@H](NC(=O)[C@@H](CCC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1)C(C)C,,CN(C)C=O,,Cl,,test
US05750705,CO.Nc1nc(Cl)c(C(F)(F)F)cc1Cl>>COc1nc(N)c(Cl)cc1C(F)(F)F,,CN(C)C=O,,[K+].[OH-],,test
US20140364432A1,C[C@@H]1CCCN[C@@H]1CN1C(=O)c2ccccc2C1=O.O=C(O)c1cc(Cl)ccc1I>>C[C@@H]1CCCN(C(=O)c2cc(Cl)ccc2I)[C@@H]1CN1C(=O)c2ccccc2C1=O,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070265289A1,CC(C)(C)OC(=O)N1CCCC(c2cc(-c3c(O)cccc3O)nc(N)n2)C1.CC1CC1CO>>CC1CC1COc1cccc(O)c1-c1cc(C2CCCN(C(=O)OC(C)(C)C)C2)nc(N)n1,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100261679A1,CC(=O)OC(C)=O.Nc1cc(Oc2ccc3nc(Nc4ccccc4N4CCOCC4)ncc3c2)ccn1>>CC(=O)Nc1cc(Oc2ccc3nc(Nc4ccccc4N4CCOCC4)ncc3c2)ccn1,,ClCCl,,CCN(CC)CC,,test
US20160016966A1,Cn1cc(Br)c2oc(C=O)cc2c1=O>>Cn1cc(Br)c2oc(CO)cc2c1=O,,CCO,,[BH4-].[Na+],,test
US20160060254A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(N)=S.O=C(CCl)c1ccc2c(c1)CCN2>>CC(C)(C)OC(=O)N1CCc2cc(-c3csc(N)n3)ccc21,CN(C)c1ccncc1,CCO,,CCN(C(C)C)C(C)C,,test
US20060142373A1,COC(=O)c1ccc2c(c1)N(C(C)=O)C(=O)C2=C(OC)c1ccccc1>>O=C1Nc2cc(C(=O)O)ccc2C1=C(O)c1ccccc1,,CO,,Cl,[Na+].[OH-],test
US05985901,COC(=O)c1ccc(-c2cccnc2)cc1>>O=Cc1ccc(-c2cccnc2)cc1,,ClCCl,,CC(C)C[Al+]CC(C)C.[H-],,test
US20150152108A1,COC(=O)c1ccc2c(n1)N[C@H]1CCN2C1.O=c1nc2ccccn2c(=O)n1-c1ccccn1>>O=C(O)c1ccc2c(n1)N(C(=O)Nc1ccccn1)[C@H]1CCN2C1,,C1CCOC1,ClCCl,CO,[H-].[Na+],test
US20040009995A1,CS(=O)(=O)CCCC(=O)Cl.CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2N)c1>>CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2NC(=O)CCCS(C)(=O)=O)c1,,ClCCl,,CCN(CC)CC,,test
US20030166639A1,Cc1cc(C2CC2)ncc1-c1cccc(C(=O)CC(=O)Nc2cc(C(F)(F)F)c(OCC(F)(F)F)cc2NC(=O)OC(C)(C)C)c1>>Cc1cc(C2CC2)ncc1-c1cccc(C2=Nc3cc(OCC(F)(F)F)c(C(F)(F)F)cc3NC(=O)C2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070049587A1,COC(=O)[C@@H]1C[C@H](NC(=O)c2ccc(Cl)s2)[C@@H](O)C1>>O=C(N[C@H]1C[C@@H](C(=O)O)C[C@@H]1O)c1ccc(Cl)s1,,CO,,[Na+].[OH-],,test
US20050090477A1,C[C@@H]1CC2=CC(=O)CC[C@@H]2[C@H]2[C@@H](F)C[C@]3(C)[C@@H](O)CC[C@H]3[C@H]12.NS(=O)(=O)c1ccc(C(=O)O)cc1>>C[C@@H]1CC2=CC(=O)CC[C@@H]2[C@H]2[C@@H](F)C[C@]3(C)[C@@H](OCc4ccc(S(N)(=O)=O)cc4)CC[C@H]3[C@H]12,,c1ccncc1,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20150313853A1,COc1ccccc1NC(=O)c1c(N)cccc1Sc1ccc([N+](=O)[O-])cc1.O=S(=O)(O)O>>COc1ccccc1NC(=O)c1c(N)cccc1Sc1ccc([N+](=O)[O-])cc1.O=S(=O)(O)O,,CCOC(C)=O,,,,test
US20140031349A1,CCC1=C(N2CCC3(CCN(C(=O)OC(C)(C)C)CC3)C2=O)COC1=O>>CCC1=C(N2CCC3(CCNCC3)C2=O)COC1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020165241A1,CC(C)(C)OC(=O)N1CCC(CNc2nccnc2Cl)CC1.CO>>COc1nccnc1NCC1CCN(C(=O)OC(C)(C)C)CC1,,CO,,C[O-].[Na+],,test
US20120088767A1,BrCc1cccc2ccccc12.COC(=O)c1cc(N2CCOCC2)cc2nc(C)[nH]c12>>COC(=O)c1cc(N2CCOCC2)cc2c1nc(C)n2Cc1cccc2ccccc12,,O,,O=C([O-])[O-].[K+].[K+],,test
US20020072603A1,O=C(Cl)C(c1ccc(Cl)cc1)c1c(Cl)cc(-n2ncc(=O)[nH]c2=O)cc1Cl>>O=c1cnn(-c2cc(Cl)c(C(CO)c3ccc(Cl)cc3)c(Cl)c2)c(=O)[nH]1,,C1COCCO1,,Cl,[BH4-].[Na+],test
US20090274632A1,COC(=O)c1ccc(S(=O)(=O)Cl)cc1.COc1ccc(N)cc1>>COC(=O)c1ccc(S(=O)(=O)Nc2ccc(OC)cc2)cc1,,ClCCl,,CCN(CC)CC,,test
US20090082372A1,CC(=O)NC(CO)Cc1c[nH]c2cccnc12>>NC(CO)Cc1c[nH]c2cccnc12,,Cl,,,,test
US20130072467A1,CCN(CC)CCOCCNC1=NC(=O)SC1.O=CC1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1>>CCN(CC)CCOCCNC1=NC(=O)S/C1=C\C1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1,,CC(C)O,,C1CC[NH2+]CC1.CC(=O)[O-],,test
US04517195,O=C(c1ccccc1Cl)c1cccn1N1C(=O)c2ccccc2C1=O>>Nn1cccc1C(=O)c1ccccc1Cl,,CCO,O,CN,,test
US05753678,BrCCC=C1c2ccccc2OCOc2ccccc21.CCOC(=O)C1CCNCC1>>CCOC(=O)C1CCN(CCC=C2c3ccccc3OCOc3ccccc32)CC1,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20110152299A1,CI.COC(=O)c1ccc(F)c(Nc2cncnc2)c1>>COC(=O)c1ccc(F)c(N(C)c2cncnc2)c1,,C1CCOC1,,CO,[H-].[Na+],test
US20150191465A1,C[C@H](NC(=O)OC(C)(C)C)c1nc2ccn(C)c2cc1N1CCCC(N2C(=O)c3ccccc3C2=O)C1>>C[C@H](N)c1nc2ccn(C)c2cc1N1CCC[C@H](N2C(=O)c3ccccc3C2=O)C1,,C1COCCO1,Cl,,,test
US05623068,N.Nc1nc2c(ncn2[C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1.O=C(Cl)Cc1ccccc1.c1ccncc1>>N#N.Nc1nc2c(ncn2[C@@]2(C(=O)Cc3ccccc3)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1,,O,c1ccncc1,C[Si](C)(C)Cl,,test
US20080111107A1,C=C[C@@H]1CC[C@@H](C(=O)O)CC1.CO>>C=C[C@@H]1CC[C@@H](C(=O)OC)CC1,,CO,,C[Si](C)(C)Cl,,test
US20060137207A1,COc1cc(-c2oc3cc(I)ccc3c(=O)c2O)cc(OC)c1OCc1ccccc1.ClCc1ccccc1>>COc1cc(-c2oc3cc(I)ccc3c(=O)c2OCc2ccccc2)cc(OC)c1OCc1ccccc1,,CC(C)=O,,[I-].[K+],,test
US20040097471A1,C=C[C@H]1[C@H](NC(=O)OCc2ccccc2)C[C@H](C(=O)OC(C)(C)C)N1Cc1ccccc1.CI>>C=C[C@H]1[C@H](N(C)C(=O)OCc2ccccc2)C[C@H](C(=O)OC(C)(C)C)N1Cc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20140329867A1,CCC(C)(C)c1ccc(O)cc1.O=[N+]([O-])c1ccc(Cl)nc1>>CCC(C)(C)c1ccc(Oc2ccc([N+](=O)[O-])cn2)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05328910,Cc1nc(NCCc2ccccc2)c2c(n1)N(c1ccccc1)C(=O)C2>>Cc1nc(NCCc2ccccc2)c2c(n1)N(c1ccccc1)CC2,,C1CCOC1,,Cl,[Na+].[OH-],test
US20150065507A1,CC(C)(C)OC(=O)N1CC[C@H](CO)[C@H](F)C1.Cc1cc(C(C)C)cnc1N(CC(C)C)S(=O)(=O)c1ccc(F)cc1>>Cc1cc(C(C)C)cnc1N(CC(C)C)S(=O)(=O)c1ccc(OC[C@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2F)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20120077828A1,Cc1cc(F)cc(CC(=O)O)c1.Nc1nccc2occ(-c3ccc4c(c3)CCN4)c12>>Cc1cc(F)cc(CC(=O)N2CCc3cc(-c4coc5ccnc(N)c45)ccc32)c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05827868,C1COCCO1.CC(C)=O.COC(C)(C)OC.Cc1ccc(S(=O)(=O)O)cc1>>OCC1OC1COCc1ccccc1,,CC(C)=O,CCOCC,,,test
US05312820,CCCCCN(Cc1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1)C(=O)Cl.c1ccc(CNc2ccccc2)cc1>>CCCCCN(Cc1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1)C(=O)N(Cc1ccccc1)c1ccccc1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20060183791A1,CCOC(=O)Nc1ccc([N+](=O)[O-])cc1OC>>CCOC(=O)Nc1ccc(N)cc1OC,[Fe],CCO,,Cl,O=C([O-])O.[Na+],test
US20150353581A1,CC(N)(C#N)COc1cc(Cl)c2c(c1)B(O)OC2.O=C(O)c1ccc(OC(F)(F)F)cc1>>CC(C#N)(COc1cc(Cl)c2c(c1)B(O)OC2)NC(=O)c1ccc(OC(F)(F)F)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05234931,CN1C2CCC1CC(C(=O)c1ccccc1F)C2.NN>>CN1C2CCC1CC(c1n[nH]c3ccccc13)C2,,CCO,,O,,test
US20030069434A1,CNCC=C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.C[C@]12C[C@H](F)[C@@H]3c4ccc(O)cc4C[C@@H](CCCCCI)[C@H]3[C@@H]1CCC2=O>>CN(CC=C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)CCCCC[C@@H]1Cc2cc(O)ccc2[C@H]2[C@@H](F)C[C@]3(C)C(=O)CC[C@H]3[C@H]12,,CN1CCCC1=O,,,,test
US20060003998A1,OC(Cc1ccccc1C(F)(F)F)(c1ccccc1)C1CN(Cc2ccccc2)CCO1>>O[C@@](Cc1ccccc1C(F)(F)F)(c1ccccc1)[C@H]1CNCCO1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20130102462A1,Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(C)O>>CC(=O)c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1C,,ClCCl,,O=C([O-])O.[Na+],,test
US20090281092A1,CCBr.COc1cc(C(=O)NN2CCNCC2)ccc1Nc1ncc2c(n1)N(C1CCCCC1)CC(F)(F)C(=O)N2C>>CCN1CCN(NC(=O)c2ccc(Nc3ncc4c(n3)N(C3CCCCC3)CC(F)(F)C(=O)N4C)c(OC)c2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20140171309A1,CC(C)N(NC(=O)OC(C)(C)C)C(=O)NCC(F)(F)F.Cl>>CC(C)N(N)C(=O)NCC(F)(F)F.Cl,,C1COCCO1,,,,test
US20150051173A1,COc1cc(C=O)cc(OC)c1OC>>COc1cc(O)c(C=O)cc1OC,,ClCCl,,BrB(Br)Br,O,test
US20050137221A1,COc1ccc(S(=O)(=O)N2C[C@@H]3OC(C)(C)O[C@H]3[C@H](O)[C@@H]2C(=O)NOCc2ccccc2)cc1>>COc1ccc(S(=O)(=O)N2C[C@H](O)[C@@H](O)[C@H](O)[C@@H]2C(=O)NOCc2ccccc2)cc1,,C1COCCO1,CO,,,test
US06358971B1,COc1ccc(-c2c(NC(=O)C(F)(F)F)nc3ccc(C(=O)c4ccccc4)cn23)cc1>>COc1ccc(-c2c(N)nc3ccc(C(=O)c4ccccc4)cn23)cc1,,CCOC(C)=O,,,,test
US06380288B1,NNS(=O)(=O)c1ccccc1.O=Cc1ccco1>>O=S(=O)(NN=Cc1ccco1)c1ccccc1,,CO,,,,test
US05208247,CC(=O)NCc1ccccn1.CCCCCCCCCCCCCCOc1cc(C(=O)Cl)ccc1OC>>CCCCCCCCCCCCCCOc1cc(C(=O)N(Cc2ccccn2)C(C)=O)ccc1OC,,C1CCOC1,,[H-].[Na+],,test
US20090203636A1,ClCOC(COCc1ccccc1)COCc1ccccc1.Nc1ncnc2nc[nH]c12>>Nc1ncnc2c1ncn2COC(COCc1ccccc1)COCc1ccccc1,,CCCCCC,CN(C)C=O,[H-].[Na+],,test
US20130178505A1,COc1cc2c(cc1OC)C(=O)C(Br)CC2.NNC(N)=S>>COc1cc2c(cc1OC)-c1nc(NN)sc1CC2,,C1COCCO1,,,,test
US20150119405A1,C=CC(=O)Cl.COc1cc(OC)c(Cl)c(-c2ccc3nc(N[C@@H]4C[C@H](C(=O)N(C)C)C[C@@H]4N)ncc3c2)c1Cl>>C=CC(=O)N[C@H]1C[C@@H](C(=O)N(C)C)C[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)ccc2n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04751295,CON=C(C(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(C=CCI)CS[C@H]12)c1nsc(N)n1.NC(=O)c1cccnc1>>CON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=C(C=CC[n+]3cccc(C(N)=O)c3)CS[C@H]12)c1nsc(N)n1,,CS(C)=O,,CCOC(C)=O,,test
US20060148858A1,COCOCCCc1c[nH]nc1C(C)C.CSc1ncc(C(F)(F)F)cn1>>CC(C)c1nn(-c2ncc(C(F)(F)F)cn2)cc1CCCO,,CN(C)C=O,O,[H][H],[H-].[Na+],test
US20120289474A1,Cl.Cn1cnc(Cn2c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c(=O)c3sc(-c4ccccc4)cc32)n1>>Cl.Cn1cnc(Cn2c(=O)n(C3CCNCC3)c(=O)c3sc(-c4ccccc4)cc32)n1,,C1COCCO1,,,,test
US20150299219A1,NC(=O)c1nccc(Cl)c1Cl.Nc1ccc(O)cc1>>NC(=O)c1nccc(Oc2ccc(N)cc2)c1Cl,,CN(C)C=O,,Cl,CC(C)(C)[O-].[K+],test
US04514429,CC(S)CS.O=Cc1ccco1>>CC1CSC(c2ccco2)S1,,C1CCCCC1,,,,test
US20090004185A1,CC(=O)c1ccc2c(NCc3ccc(NC(=O)c4ccc(F)cc4)cc3)nc(N(C)C)nc2c1>>CC(O)c1ccc2c(NCc3ccc(NC(=O)c4ccc(F)cc4)cc3)nc(N(C)C)nc2c1,,CO,,[BH4-].[Na+],,test
US20110237573A1,CC(=O)N1CCN(c2ccc([N+](=O)[O-])nc2)CC1>>CC(=O)N1CCN(c2ccc(N)nc2)CC1,[Pd],CO,,[H][H],,test
US20090137603A1,N#Cc1cccc(OCCCl)c1.Sc1nc[nH]n1>>N#Cc1cccc(OCCSc2nc[nH]n2)c1,,CCO,,CCN(CC)CC,,test
US20080021032A1,CCCC(Br)c1ccc(C(=O)OC)cc1.O=[N+]([O-])c1cc[nH]n1>>CCCC(c1ccc(C(=O)OC)cc1)n1ccc([N+](=O)[O-])n1,,CN(C)C=O,,[H-].[Na+],,test
US20040132714A1,N#Cc1ccc2[nH]cc(CC3CN(C(c4ccccc4)c4ccccc4)C3)c2c1>>Cc1ccc2[nH]cc(CC3CNC3)c2c1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20060128734A1,CCc1ccc(NC(=O)Nc2ccc(Cc3cc(N)ncn3)cc2)cc1>>Cc1ccc(NC(=O)Nc2ccc(Cc3cc(N)ncn3)cc2)cc1,,CN(C)C=O,,,,test
US20100121091A1,CCCCS(=O)(=O)Cl.O=C(NCCOC1CCCCO1)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1N(CCO)CCBr>>CCCCS(=O)(=O)OCCN(CCBr)c1c(C(=O)NCCOC2CCCCO2)cc([N+](=O)[O-])cc1[N+](=O)[O-],,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20150065522A1,CN(C)/C=C(\C#N)n1cnc(-c2cscn2)c1.NN>>Nc1[nH]ncc1-n1cnc(-c2cscn2)c1,,CCO,O,Cl,,test
US20110046133A1,Cc1ccc(N)cc1C.O=C(O)c1ccc2cc(-c3c(Cl)cccc3Cl)[nH]c2c1>>Cc1ccc(NC(=O)c2ccc3cc(-c4c(Cl)cccc4Cl)[nH]c3c2)cc1C,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06337332B1,COc1cccc2c(=O)n(CCCC3CCN(C(=O)OC(C)(C)C)CC3)c(C)nc12.O=C1CCC(=O)N1Br>>COc1cccc2c(=O)n(CCCC3CCN(C(=O)OC(C)(C)C)CC3)c(CBr)nc12,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US04511390,CC(C)C[C@H](N)CO.O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1>>CC(C)C[C@@H](CO)NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1,,C1CCOC1,CC(C)=O,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20150216175A1,CCn1c(C(=O)NC(c2ccc(F)c(C(F)(F)F)c2)C(F)(F)F)cc2nc(C(=O)OC)ccc21.NC1CC1>>CCn1c(C(=O)NC(c2ccc(F)c(C(F)(F)F)c2)C(F)(F)F)cc2nc(C(=O)NC3CC3)ccc21,,ClCCl,,C[Al](C)C,,test
US20070155726A1,ICCOc1ccc(Cc2ccc(-c3ncco3)cc2)cc1.NCCN1CCOCC1>>c1coc(-c2ccc(Cc3ccc(OCCNCCN4CCOCC4)cc3)cc2)n1,,ClCCl,,,,test
US20120065199A1,CC(=O)OCCl.CNC(=O)c1ccc2ncc(C(=O)O)c(Nc3ccc(OC)cc3)c2c1>>CNC(=O)c1ccc2ncc(C(=O)OCOC(C)=O)c(Nc3ccc(OC)cc3)c2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04349684,COC(=O)CCCCCCCCn1cc(-c2ccccc2)n(-c2ccc(Cl)cc2)c1=O>>O=C(O)CCCCCCCCn1cc(-c2ccccc2)n(-c2ccc(Cl)cc2)c1=O,,CO,,[Na+].[OH-],,test
US20060217382A1,COc1ccc(Nc2ncc(C(C)NC(=O)c3ccccc3Cl)nn2)cc1>>COc1ccc(Nc2ncc3c(C)nc(-c4ccccc4Cl)n3n2)cc1,,ClCCCl,,O=P(Cl)(Cl)Cl,,test
US20160031857A1,CCOC(=O)Cc1ccc(Nc2nc(-c3ccc(Cl)s3)nc3c2CCC3)c(N)c1.CCOC(OCC)OCC>>CCOC(=O)Cc1ccc2c(c1)ncn2-c1nc(-c2ccc(Cl)s2)nc2c1CCC2,,CCOC(C)=O,,,,test
US20080090825A1,CC(=O)OC(C)=O.CCC(O)(C(=O)O)C(Cc1ccc(O[Si](C)(C)C(C)(C)C)cc1)C(=O)O>>CCC1=C(Cc2ccc(OC(C)=O)cc2)C(=O)OC1=O,,CCOC(C)=O,Cc1ccccc1,,,test
US20090318470A1,CN1CCN(c2ccc([N+](=O)[O-])cc2)CC1.O=S(=O)(CCl)c1cccc2ccccc12>>CN1CCN(c2ccc([N+](=O)[O-])c(CS(=O)(=O)c3cccc4ccccc34)c2)CC1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20150158865A1,CCOC(=O)c1nnc(SC)nc1Cl.COC(=O)c1ccc(N)cc1.N>>COC(=O)c1ccc(Nc2nc(SC)nnc2C(N)=O)cc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20100009975A1,CC(C)(C)OC(=O)N1CCC(Nc2cc([N+](=O)[O-])ccc2SCCO)CC1.II>>CC(C)(C)OC(=O)N1CCC(Nc2cc([N+](=O)[O-])ccc2SCCI)CC1,,C1CCOC1,CCOC(C)=O,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110144066A1,CCCCCCCCCCCCc1ccc(S(=O)(=O)Cl)cc1.Nc1nnc(CO)s1>>CCCCCCCCCCCCc1ccc(S(=O)(=O)Nc2nnc(CO)s2)cc1,,c1ccncc1,,Cl,,test
US20040034047A1,COc1cc(Cc2cnc(N)nc2N)c2cc(C3(c4ccccc4)OCCO3)oc2c1OC>>COc1cc(Cc2cnc(N)nc2N)c2cc(C(=O)c3ccccc3)oc2c1OC,,CCO,,Cl,,test
US20080261969A1,FC1(F)Oc2cc3[nH]c(=S)[nH]c3cc2O1.O=Cc1ccc([N+](=O)[O-])o1>>O=Cc1ccc(Sc2nc3cc4c(cc3[nH]2)OC(F)(F)O4)o1,,C1CCOC1,,[H-].[Na+],,test
US20120238559A1,C[Sn](C)(C)c1cc(N)c2cnn(S(=O)(=O)c3ccccc3)c2c1.O=C(Cl)c1ccco1>>C[Sn](C)(C)c1cc(NC(=O)c2ccco2)c2cnn(S(=O)(=O)c3ccccc3)c2c1,,c1ccncc1,,Cl,,test
US20080227826A1,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(Cl)nc1.N[C@H]1CCNC1>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(N2CC[C@H](N)C2)nc1,,CS(C)=O,O,,,test
US20150225379A1,C=CC(=O)OC.C=CCOC(=O)N(CC1(COc2ccc(F)cn2)CCNCC1)[C@@H]1C[C@H]1c1ccccc1>>C=CCOC(=O)N(CC1(COc2ccc(F)cn2)CCN(CCC(=O)OC)CC1)[C@@H]1C[C@H]1c1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20110301370A1,COC(=O)CCCCCO>>COC(=O)CCCCC=O,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US04748163,NC(C(=O)O)c1ccc2[nH]c(C(F)(F)F)nc2c1.O=C(Cl)OCc1ccccc1>>O=C(NC(C(=O)O)c1ccc2[nH]c(C(F)(F)F)nc2c1)OCc1ccccc1,,O,,[Na+].[OH-],,test
US06982257B1,C[C@@H](CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)[C@@H](CC#C[Si](C)(C)C)OC1CCCCO1>>C#CC[C@@H](OC1CCCCO1)[C@@H](C)CO,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20050032864A1,CCOC(=O)Cl.CCc1nc(C)cc(=O)n1CCOc1ccc(CN(O)C(N)=O)cc1>>CCc1nc(C)cc(=O)n1CCOc1ccc(Cn2oc(=O)[nH]c2=O)cc1,,O,,[Na+].[OH-],,test
US20090233937A1,CS(=O)(=O)O.O=C(NCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(Cl)c3)c21)C(F)F>>CS(=O)(=O)ON(CCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(Cl)c3)c21)C(=O)C(F)F,,CCOC(C)=O,,CCOCC,,test
US20080227797A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](NC(=O)c2cc(F)cnc2Nc2cccc(S(C)(=O)=O)c2)CC1.O=C(n1ccnc1)n1ccnc1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(S(C)(=O)=O)c3)c2=O)CC1,,CN1CCCC1=O,,CCOC(C)=O,[H-].[Na+],test
US20120329785A1,CN(C)c1cccc(N)c1.COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1>>COc1ccc2nc(Nc3cccc(N(C)C)c3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US05001125,FC(F)(F)c1cccc(N2CCNCC2)c1.Fc1ccc(F)nn1>>Fc1ccc(N2CCN(c3cccc(C(F)(F)F)c3)CC2)nn1,,O,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20130005707A1,COc1cc([N+](=O)[O-])c(Br)nc1Br>>COc1cncc(N)c1,[Pd],CO,,[H][H],,test
US20130059849A1,CCOC(=O)c1cc(C2CC2)nc2c1c(C)nn2C1CCOCC1>>Cc1nn(C2CCOCC2)c2nc(C3CC3)cc(C(=O)O)c12,,CCO,,[Na+].[OH-],,test
US20080255122A1,CC(C)N1C(=O)C(Cl)=C(c2ccccc2)S1(=O)=O.Nc1ccc(N2CCOCC2)cc1>>CC(C)N1C(=O)C(Nc2ccc(N3CCOCC3)cc2)=C(c2ccccc2)S1(=O)=O,,CC#N,,,,test
US07829584B2,N#Cc1ccc(Cl)nc1CC(=O)O.O=[N+]([O-])c1ccc(O)cc1>>N#Cc1ccc(Cl)nc1CC(=O)Oc1ccc([N+](=O)[O-])cc1,CN(C)c1ccncc1,ClCCl,,CC(C)N=C=NC(C)C,,test
US20010031760A1,CCN(CC)CC.COC(=O)C1CCNCC1.Clc1ccc2nc(Cl)nc(NCc3ccc4c(c3)OCO4)c2c1>>CCOC(=O)C1CCN(c2nc(NCc3ccc4c(c3)OCO4)c3cc(Cl)ccc3n2)CC1,,CC(C)O,,,,test
US20130065893A1,CC(F)(F)c1ccc(I)cc1.N#Cc1ccc([C@H]2CC(=O)c3cncn32)c(F)c1>>CC(F)(F)c1ccc([C@@]2(O)C[C@H](c3ccc(C#N)cc3F)n3cncc32)cc1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20120244171A1,COCCOCCOCCN(CC(C)(C)SSC)c1cc(CO[Si](C)(C)C(C)(C)C)cc(CO[Si](C)(C)C(C)(C)C)c1>>COCCOCCOCCN(CC(C)(C)SSC)c1cc(CO)cc(CO)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090209755A1,CC(C)(C)OC(=O)N(C(=O)c1ccccc1)C1=N[C@@]2(c3cc(Br)cs3)CCOC[C@H]2CS1.OB(O)c1cccnc1F>>NC1=N[C@@]2(c3cc(-c4cccnc4F)cs3)CCOC[C@H]2CS1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US20130172302A1,CCOC(=O)C(Br)c1ccccc1.CN1CCNCC1=O>>CCOC(=O)C(c1ccccc1)N1CCN(C)C(=O)C1,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20140171405A1,CN1CCC(N)CC1.COC(=O)c1ccc(Br)cc1CBr>>CN1CCC(N2Cc3cc(Br)ccc3C2=O)CC1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20060194850A1,COC(=O)CCSCc1ccc(-c2oncc2C(=O)OC(C)(C)C)cc1>>COC(=O)CCSCc1ccc(-c2oncc2C(=O)O)cc1,,C1COCCO1,,Cl,,test
US04289524,C1OCOCO1.CNC(=S)Nc1nc2c(s1)C(C)CC(C)(C)C2.O>>CC1CC(C)(C)Cc2nc(N3COCN(C)C3=O)sc21,,O,,[Na+].[OH-],,test
US05053415,CCOC(=O)C(C)(C)Oc1ccc(C)cc1[N+](=O)[O-]>>Cc1ccc(OC(C)(C)C=O)c([N+](=O)[O-])c1,,Cc1ccccc1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20020173526A1,Fc1ccc(/C=C/c2nc(CCl)co2)c(F)c1.OCCCCc1ccc(O)cc1>>OCCCCc1ccc(OCc2coc(/C=C/c3ccc(F)cc3F)n2)cc1,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20120149684A1,BrCCOC1CCCCO1.CC(C)(C)OC(=O)N1CCC(c2nc(C3CCOCC3)c[nH]2)CC1>>CC(C)(C)OC(=O)N1CCC(c2nc(C3CCOCC3)cn2CCOC2CCCCO2)CC1,,CS(C)=O,,[K+].[OH-],,test
US04151303,CCOC(=O)C(C)(C)Oc1ccc(CCN)cc1.O=C(O)C=Cc1ccccc1Cl>>CCOC(=O)C(C)(C)Oc1ccc(CCNC(=O)C=Cc2ccccc2Cl)cc1,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US20120309755A1,NC(=O)c1cc(F)c(Cl)c([N+](=O)[O-])c1Cl>>NC(=O)c1cc(F)c(Cl)c(N)c1Cl,,CCOC(C)=O,,O=C([O-])O.[Na+],,test
US20060240190A1,C[Si](C)(C)Cl.[Na]C1C=CC=C1>>C[Si](C)(C)C1=CC=CC1,,C1CCOC1,,,,test
US20110105472A1,CC(C)Oc1ccc(N)cc1.Cl.Clc1ncc(Cl)c(NC2CCC2)n1>>CC(C)Oc1ccc(Nc2ncc(Cl)c(NC3CCC3)n2)cc1.Cl,,C1COCCO1,CC#N,,,test
US20080153837A1,CCN(CC)CC.N#Cc1ccc(N)c(N)c1.O=C(Cl)C1=c2ccccc2=C2C(=O)C=CC=C12>>CC(C)OC(C)C.N#Cc1ccc(N)c([NH-])c1,,ClCCl,,C1CCOC1,,test
US20080090827A1,CC(C)(C)C(=O)Cl.OCCc1ccc(O)cc1>>CC(C)(C)C(=O)Oc1ccc(CCO)cc1,,ClCCl,,CCN(CC)CC,,test
US20120058988A1,CC(C)(C)OC(=O)N1CCNCC1.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc([N+](=O)[O-])cc2)CC1,,CCOC(C)=O,ClCCl,Cl,c1ccncc1,test
US20100298324A1,COC(=O)c1ccc(C(=O)OC)c(N=C=S)c1.Nc1ncccn1>>O=C(O)c1ccc2c(=O)n(-c3ncccn3)c(=S)[nH]c2c1,,CN(C)C=O,,Cl,[Na+].[OH-],test
US20050038016A1,CSCCl.O=Cc1cccc(O)c1>>CSCOc1cccc(C=O)c1,,CC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20040259912A1,COC(=O)c1cc([N+](=O)[O-])ccc1OC(c1ccccc1)c1ccc(C(F)(F)F)cc1>>COC(=O)c1cc(N)ccc1OC(c1ccccc1)c1ccc(C(F)(F)F)cc1,[Fe],CCO,O,[Ca+2].[Cl-].[Cl-],,test
US20030212012A1,COC(=O)[C@@H]1CC(=O)CN1C(=O)OC(C)(C)C.N#CCO[PH](=O)[O-]>>C=C1C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C1,,C1CCOC1,CCOC(C)=O,[H-].[Na+],[Cl-].[NH4+],test
US20050032786A1,COC(=O)c1ccccc1S.N#Cc1cccc(Sc2ncccn2)n1>>O=c1nc(-c2cccc(Sc3ncccn3)n2)sc2ccccc12,,Cc1ccccc1,,CCN(CC)CC,,test
US20060014777A1,CC(=O)Cl.Cc1cccc2c1CN[C@@H]1CN(Cc3ccccc3)C[C@@H]21>>CC(=O)N1Cc2c(C)cccc2[C@@H]2CN(Cc3ccccc3)C[C@H]21,,ClCCl,,CCN(CC)CC,,test
US20110275611A1,CNc1nc(Cl)cc(N2C[C@@H](C(=O)NC3CCCCC3)CC[C@H]2C(F)(F)F)n1.N#Cc1ccc(B(O)O)cc1F>>CNc1nc(-c2ccc(C#N)c(F)c2)cc(N2C[C@@H](C(=O)NC3CCCCC3)CC[C@H]2C(F)(F)F)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])O.[Na+],,test
US20100152047A1,CCI.CN1C(=O)C(Cc2ccccc2)N(C)C(=O)C1=Cc1ccccc1C#N>>CCC1(Cc2ccccc2)C(=O)N(C)C(=Cc2ccccc2C#N)C(=O)N1C,,CN(C)C=O,,O,[H-].[Na+],test
US04725608,O=C(N=[N+]1C=CC=CC1)Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)NN1CC=CCC1,,CCO,,O,[BH4-].[Na+],test
US20050267095A1,CCOC(=O)N1CCNCC1.ClCCCBr>>CCOC(=O)N1CCN(CCCCl)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070213371A1,CI.Cn1nnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)Cc2cc(C(F)(F)F)ccc2C(O)C2CCN(C(=O)OC(C)(C)C)CC2)n1>>COC(c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1)C1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,[H-].[Na+],,test
US20090099172A1,CCOC(OCC)OCC.N#Cc1nc(Cl)cc(N)c1N>>N#Cc1nc(Cl)cc2[nH]cnc12,,ClCCl,,CC(=O)O,,test
US20040138254A1,N#Cc1cccc(F)c1OCc1ccccc1.c1cn[nH]c1>>N#Cc1ccc(-n2cccn2)cc1OCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20140113882A1,COc1cncc2nc(-c3ccncc3)nc(N3CCC(NC(=O)OC(C)(C)C)(C(=O)Nc4ccccc4)C3)c12>>COc1cncc2nc(-c3ccncc3)nc(N3CCC(N)(C(=O)Nc4ccccc4)C3)c12,,CS(C)=O,,ClCCl,O=C(O)C(F)(F)F,test
US20040209886A1,O=[N+]([O-])c1ccc(F)cc1.Oc1ccccc1O>>O=[N+]([O-])c1ccc(Oc2ccccc2O)cc1,,CC(=O)N(C)C,,Cl,CC(C)(C)[O-].[K+],test
US20130084346A1,Br[Mg]C#Cc1ccccc1.COc1ccc(COc2cn(-c3cccc(-c4c(Cl)cnc5[nH]ccc45)c3)c(C=O)cc2=O)cc1>>O=c1cc(C(O)C#Cc2ccccc2)n(-c2cccc(-c3c(Cl)cnc4[nH]ccc34)c2)cc1O,,C1CCOC1,,O,,test
US20040110804A1,CO.CON(Cc1ccc(Cl)cc1)C(=O)C=C1OC(C)(C)OC1=O>>COC(=O)C(O)=CC(=O)N(Cc1ccc(Cl)cc1)OC,,CO,,,,test
US20060217567A1,CC(C)=O.Cc1ccccc1.Nc1ccc(Cc2ccc(N)cc2)cc1>>CC(C)Nc1ccc(Cc2ccc(NC(C)C)cc2)cc1,[Pt],,,,,test
US04545995,CCN(CC)CC=CCc1ccc(N)cc1.CS(=O)(=O)Cl>>CCN(CC)CC=CCc1ccc(NS(C)(=O)=O)cc1,,ClCCl,,,,test
US20070213325A1,CN1CCN(CCCN)CC1.CS(=O)(=O)c1nccc(-c2cccnc2Oc2ccc(Nc3nc4cc(F)c(F)cc4[nH]3)cc2)n1>>CN1CCN(CCCNc2nccc(-c3cccnc3Oc3ccc(Nc4nc5cc(F)c(F)cc5[nH]4)cc3)n2)CC1,,ClCCl,,CC(C)O,,test
US20130225552A1,COc1nc2cccnc2n1[C@@H]1C[C@@H](NC(=O)OC(C)(C)C)C1.Fc1ccc2nc(Cl)sc2c1>>O=c1[nH]c2cccnc2n1[C@@H]1C[C@@H](Nc2nc3ccc(F)cc3s2)C1,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US20140315881A1,Cc1noc(C)c1-c1nc2ccc(CC(=O)Cl)cc2[nH]1.OCc1ccccc1>>Cc1noc(C)c1-c1nc2ccc(CC(=O)OCc3ccccc3)cc2[nH]1,,ClCCl,,,,test
US05155113,O.O=C(Cl)c1cccc(C(=O)Cl)c1.O=c1cc(O)cc[nH]1>>O=C(O)c1cccc(C(=O)Oc2cc[nH]c(=O)c2)c1,,c1ccncc1,,,,test
US05116844,CCc1ccnnc1.O=C(Cn1cncn1)c1ccc(Cl)cc1Cl>>CC(c1ccnnc1)C(O)(Cn1cncn1)c1ccc(Cl)cc1Cl,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US05955607,CN(CCO)Cc1ccccc1.Cc1ccc2c(c1)C(N(CCCCC(=O)O)S(C)(=O)=O)CC(C)(C)O2>>Cc1ccc2c(c1)C(N(CCCCC(=O)OCCNCCc1ccccc1)S(C)(=O)=O)CC(C)(C)O2,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20140163001A1,CCOC(=O)c1cnn(C(C)(C)C)c1-c1ccc(OC)cc1>>COc1ccc(-c2c(C(=O)O)cnn2C(C)(C)C)cc1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20020072611A1,CC(C)(C)OC(=O)N1CC=C(c2c[nH]c3ccc(C#N)cc23)CC1>>CC(C)(C)OC(=O)N1CCC(c2c[nH]c3ccc(C#N)cc23)CC1,[Pd],CCO,,,,test
US20160221945A1,Cl.O=C(NCc1cc(-c2cnc(C(F)(F)F)nc2)c(Cl)cn1)[C@@H]1C[C@@H](F)CN1C(=O)[O-]>>Cl.O=C(NCc1cc(-c2cnc(C(F)(F)F)nc2)c(Cl)cn1)[C@@H]1C[C@@H](F)CN1,,C1COCCO1,,,,test
US20150336979A1,CC(=O)Oc1c[nH]c2ccccc12.Cc1ccc(S(=O)(=O)O[C@@H]2CO[C@@H]3[C@@H](NC(=O)NC4CCCCC4)CO[C@H]23)cc1>>O=C(NC1CCCCC1)N[C@H]1CO[C@@H]2[C@@H](Oc3c[nH]c4ccccc34)CO[C@H]12,,CN(C)C=O,O,CC(C)(C)[O-].[K+],,test
US06087380,CCCCCCCCOC(=O)Cl.CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)N)cc1)n2C)c1cccnc1>>CCCCCCCCOC(=O)NC(=N)c1ccc(NCc2nc3cc(C(=O)N(CCC(=O)OCC)c4cccnc4)ccc3n2C)cc1,,CCO,ClCCl,Cl,,test
US05250517,C=CC(=O)OC(C)(C)C.CCOC(=O)C(Cc1ccccc1)C(=O)OCC>>CCOC(=O)C(CCC(=O)OC(C)(C)C)(Cc1ccccc1)C(=O)OCC,,CC#N,,C1CCC2=NCCCN2CC1,Cl,test
US20150087585A1,COC(OC)C(=O)C=CN(C)C.N=C(N)C1CCC1>>COC(OC)c1ccnc(C2CCC2)n1,,CCO,,CCN(CC)CC,Cl,test
US05712225,NNCCO.S=C=Nc1ccc(Cl)cc1Cl>>NN(CCO)C(=S)Nc1ccc(Cl)cc1Cl,,ClCCl,,CCN(CC)CC,,test
US20140303171A1,CC(C)(C)S(=O)NC(CO[Si](C)(C)C(C)(C)C)c1cc(Br)cs1.Cl>>[Cl-].[NH3+]C(CO)c1cc(Br)cs1,,C1COCCO1,CO,,,test
US20120316161A1,CCCC(C(=O)OCC)C(C(C)=O)C(=O)OCC.Nc1n[nH]c(Cc2ccccc2)n1>>CCCC(C(=O)OCC)c1c(C)nc2nc(Cc3ccccc3)nn2c1O,,Cc1ccccc1,,,,test
US20150291655A1,C=C(C)[C@@H]1CC[C@]2(NCC=C(C3CC3)C3CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(C(=O)OCc7ccccc7)CC6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NCC=C(C3CC3)C3CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(C(=O)O)CC6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1COCCO1,CCO,[Na+].[OH-],,test
US20130029987A1,CSc1ncc(C(N)=O)c(NC(C)C)n1.O=S(=O)(c1ccccc1)N1OC1c1ccccc1>>CC(C)Nc1nc(S(C)=O)ncc1C(N)=O,,ClC(Cl)Cl,,,,test
US20130096124A1,Cc1cc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)oc1C=O.NC(=O)C1CC1>>Cc1cc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)oc1CNC(=O)C1CC1,,Cc1ccccc1,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20050107383A1,FC(F)c1ccc(-c2c[nH]nc2C(F)(F)F)cc1C(SC(c1cc(-c2c[nH]nc2C(F)(F)F)ccc1C(F)F)C(F)(F)F)C(F)(F)F.O=C(OO)c1cccc(Cl)c1>>O=S(C(c1cc(-c2c[nH]nc2C(F)(F)F)ccc1C(F)F)C(F)(F)F)C(c1cc(-c2c[nH]nc2C(F)(F)F)ccc1C(F)F)C(F)(F)F,,ClC(Cl)Cl,,O=S([O-])[O-].[Na+].[Na+],,test
US20070088036A1,COC(=O)C1(c2ccc(Cl)cc2)CCN(C(=O)Cn2nc(C(F)(F)F)c(Cl)c2C)CC1>>Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)N1CCC(C(=O)O)(c2ccc(Cl)cc2)CC1,,O,,CCO,[Na+].[OH-],test
US20010007867A1,CCC(N)CC.Cc1cc(C)c(-c2cnn3c(Cl)cc(C)nc23)c(C)c1>>CCC(CC)Nc1cc(C)nc2c(-c3c(C)cc(C)cc3C)cnn12,,CN1CCCC1=O,,,,test
US04868301,C=O.CCOC(=O)Cc1n[nH]c(=O)c2ccccc12>>CCOC(=O)Cc1nn(CO)c(=O)c2ccccc12,,CCO,,,,test
US20150011548A1,CC(=O)Nc1cc(-c2c(F)cccc2F)cc(-n2cnc3cc(-n4cccn4)ccc32)c1>>Nc1cc(-c2c(F)cccc2F)cc(-n2cnc3cc(-n4cccn4)ccc32)c1,,CCO,,[Na+].[OH-],,test
US20100093811A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@@H](N)CCCC(N)C(=O)OC(C)(C)C>>COC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C,,CCN(CC)CC,,ClCCl,,test
US03976783,NC(=O)Cc1ccc(OCCNCc2ccccc2)cc1.O=C(CBr)c1ccc(OCc2ccccc2)c(OCc2ccccc2)c1>>NC(=O)Cc1ccc(OCCN(CC(=O)c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)Cc2ccccc2)cc1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20100179168A1,COc1ccc(N(C)C(=O)C(C)(C)N(C(=O)[O-])C(C)(C)C)cc1NS(=O)(=O)c1ccc(-c2ccc(C)o2)c(F)c1.Cl>>COc1ccc(N(C)C(=O)C(C)(C)N)cc1NS(=O)(=O)c1ccc(-c2ccc(C)o2)c(F)c1.Cl,,C1COCCO1,,,,test
US20080103202A1,CCOC(=O)CN(C)C(=N)N.O=C1O[C@H]([C@@H](O)CO)C(O)=C1O>>CCOC(=O)CN(C)C(=N)N.O=C1O[C@H]([C@@H](O)CO)C([O-])=C1O,,O,,,,test
US20130202573A1,COC(=O)CS.N#Cc1ccc(-c2ncncc2Br)c2ccccc12>>COC(=O)CSc1cncnc1-c1ccc(C#N)c2ccccc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US03963748,NC1=NCCC1.O=C=Nc1ccc(Br)cc1>>O=C(NC1=NCCC1)Nc1ccc(Br)cc1,,CC(C)=O,,Cl,[Na],test
US20090005560A1,CC(=O)Nc1cnc(-c2ccccc2)nc1Cl.NCc1ccccc1>>CC(=O)Nc1cnc(-c2ccccc2)nc1NCc1ccccc1.Cl,,CC(C)O,,CCN(CC)CC,,test
US20050165063A1,C=O.Cn1ccnc1CN(Cc1ccc(S(=O)(=O)NCCCCNC2CCCCC2)cc1)Cc1ncc[nH]1>>CN(CCCCNS(=O)(=O)c1ccc(CN(Cc2ncc[nH]2)Cc2nccn2C)cc1)C1CCCCC1,,CC(=O)O,CO,[Na+].[OH-],,test
US05256675,Nc1ccc(SCc2csc(NC=O)n2)cc1.O=CO>>O=CNc1ccc(SCc2csc(NC=O)n2)cc1,,O=CO,,CC(=O)OC(C)=O,,test
US05814627,CCOC(=O)C(=O)NCc1cc(-c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)no1>>CC(C)(C)c1cc(-c2cc(CNC(=O)C(=O)O)on2)cc(C(C)(C)C)c1O,,ClCCl,,,,test
US20040235822A1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CSc4nncs4)cc2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CS(=O)c4nncs4)cc2)CCN3CC(C)C)cc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20120157430A1,COC(=O)Cl.COc1c(C(C)Nc2ncnc3[nH]cnc23)cc(Cl)c(C)c1C1CNC1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F>>COC(=O)N1CC(c2c(C)c(Cl)cc(C(C)Nc3ncnc4[nH]cnc34)c2OC)C1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100216820A1,CCC(N)c1nc2ccsc2c(=O)n1-c1ccccc1.Fc1nc(Cl)c2ncn(C3CCCCO3)c2n1>>CCC(Nc1nc(F)nc2c1ncn2C1CCCCO1)c1nc2ccsc2c(=O)n1-c1ccccc1,,CCO,,CCN(C(C)C)C(C)C,,test
US20080004267A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc([N+](=O)[O-])cc1)C(N)=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc([N+](=O)[O-])cc1)C(N)=S,,C1CCOC1,,,,test
US20090133318A1,CC(N)C1CC1.Cc1cc(Cl)cc2c(=O)oc(-c3cc(Br)nn3-c3ncccc3Cl)nc12>>Cc1cc(Cl)cc(C(=O)NC(C)C2CC2)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl,,CC#N,,CCOCC,,test
US20100331297A1,CC(C)(C)n1nc(-c2ccc(Cl)cc2)c2c(N)ncnc21.O=C(O)C(=O)c1ccccc1>>CC(C)(C)n1nc(-c2ccc(Cl)cc2)c2c(NC(=O)C(=O)c3ccccc3)ncnc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140051706A1,CCOC(=O)OC(C)Cl.C[C@H]1C2N(C(=O)CN(C)N2C(=O)NCc2ccccc2)[C@@H](Cc2ccc(O)cc2)C(=O)N1Cc1cccc2cccnc12>>CCOC(=O)OC(C)Oc1ccc(C[C@H]2C(=O)N(Cc3cccc4cccnc34)[C@@H](C)C3N2C(=O)CN(C)N3C(=O)NCc2ccccc2)cc1,,CC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20070270438A1,N#Cc1cccc(CO)c1.NO>>NC(=NO)c1cccc(CO)c1,,CO,,Cl,O=C([O-])O.[Na+],test
US20100311747A1,BrCC1CCCCC1.CN(C)C(=O)N1CC2CC(C#N)CC2C1>>CN(C)C(=O)N1CC2CC(C#N)(CC3CCCCC3)CC2C1,,C1CCOC1,,[Cl-].[NH4+],C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20020099207A1,CCOC(=O)c1cnc(-c2ccncc2)nc1Oc1ccccc1C>>Cc1ccccc1Oc1nc(-c2ccncc2)ncc1C(=O)O,,CCO,O,Cl,[Na+].[OH-],test
US20090239854A1,CN1CCC(=O)CC1.CN1CCN(CCBr)CC1.NNc1ccc(Cl)cc1>>CN1CCN(CCn2c3c(c4cc(Cl)ccc42)CN(C)CC3)CC1,,CCN(CC)CC,,Cl,,test
US04028386,CC(=O)CCC=C(C)CCC=C(C)C.CCOC(=O)OCC>>CCOC(=O)CC(=O)CCC=C(C)CCC=C(C)C,,c1ccccc1,,Cl,[H-].[Na+],test
US05114955,O=S(Cl)Cl.OCc1cc(OCc2ccc(C(F)(F)F)cc2)ccn1>>FC(F)(F)c1ccc(COc2ccnc(CCl)c2)cc1,,ClCCl,,,,test
US20150080383A1,CC(=O)c1cc(Br)ccc1O.COc1ccc(C=O)cc1OC>>COc1ccc(/C=C/C(=O)c2cc(Br)ccc2O)cc1OC,,CCO,,Cl,[K+].[OH-],test
US20140206688A1,CC(C)Oc1cc2ncnc(Nc3ccc4scnc4c3)c2cc1SC(C)(C)C.O=S([O-])OO>>CC(C)Oc1cc2ncnc(Nc3ccc4scnc4c3)c2cc1S(=O)(=O)C(C)(C)C,,CO,,O,,test
US20030232869A1,COC(=O)c1cc([N+](=O)[O-])c(N)c(F)c1F.Nc1ccccc1F>>COC(=O)c1cc([N+](=O)[O-])c(N)c(F)c1Nc1ccccc1F,,ClCCl,,,,test
US04125732,COC(=O)C(Br)c1ccc(OCC(C)Oc2ccc(C(F)(F)F)cc2)cc1.Oc1ccc(C(F)(F)F)cc1>>COC(=O)C(Oc1ccc(C(F)(F)F)cc1)c1ccc(OCC(C)Oc2ccc(C(F)(F)F)cc2)cc1,,C1CCOC1,,,,test
US20090099155A1,NCCOc1c(Cl)ccc2c1CCN(C(=O)C(F)(F)F)CC2.O=C(O)c1ccccn1>>O=C(NCCOc1c(Cl)ccc2c1CCN(C(=O)C(F)(F)F)CC2)c1ccccn1,,ClCCl,O,ClCCCl,On1nnc2ccccc21,test
US20080255152A1,CC(C)(C)OC(=O)NCCc1ccc(O)cc1.NC(=O)c1ccc(Cl)nc1>>CC(C)(C)OC(=O)NCCc1ccc(Oc2ccc(C(N)=O)cn2)cc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20080221110A1,NC1CCN(CC2Cn3c(=O)ccc4ccc(F)c2c43)CC1.O=Cc1cc2c(nn1)OCCO2>>O=c1ccc2ccc(F)c3c2n1CC3CN1CCC(NCc2cc3c(nn2)OCCO3)CC1,,CO,ClCCl,O=C([O-])O.[Na+],,test
US20150366204A1,COc1ccc(C(N)CO)cc1.FC(F)(F)Oc1ccc(-n2cnc(-c3ccc(N=C=S)cc3)n2)cc1>>COc1ccc(C(CO)NC(=S)Nc2ccc(-c3ncn(-c4ccc(OC(F)(F)F)cc4)n3)cc2)cc1,,C1CCOC1,,,,test
US20040132769A1,CCO.O=C(O)c1ccc2cc(O)ccc2c1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CCOC(=O)Nc1ccc2cc(O)ccc2c1,,C1COCCO1,,CCN(CC)CC,,test
US20050101643A1,CCC[C@H](CC)CI.COC(=O)N1CCC(=O)N(C)[C@@H]1C(C)(C)C>>CCC[C@H](CC)C[C@@H]1CN(C(=O)OC)[C@@H](C(C)(C)C)N(C)C1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20090062251A1,CCS(=O)(=O)n1c2c(c3cc(C(=O)O)ccc31)CC(C1CCOCC1)CC2.O[C@@H]1CCNC1>>CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CC[C@@H](O)C4)ccc31)CC(C1CCOCC1)CC2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050215605A1,O=C(Cl)C(=O)Cl.O=C(O)c1ccc(Cl)nc1>>O=C(Cl)c1ccc(Cl)nc1,,ClCCl,,CN(C)C=O,,test
US20110306636A1,CC(C)(C)OC(=O)CNc1ncc(C#N)cc1Cl.NO>>CC(C)(C)OC(=O)CNc1ncc(C(N)=NO)cc1Cl,,C1CCOC1,,,,test
US20090264496A1,CCCCCCCCCCCCCCCCN=C=O.NCCc1c[nH]c2ccc(O)cc12>>CCCCCCCCCCCCCCCCNC(=O)NCCc1c[nH]c2ccc(O)cc12,,c1ccncc1,,Cl,O,test
US20120094982A1,COc1ccc(CN2C(=O)C(Cc3ccc4ccccc4c3)N=C(N3CCC4(CC3)OCCO4)c3cc(Cl)ccc32)cc1>>O=C1CCN(C2=NC(Cc3ccc4ccccc4c3)C(=O)Nc3ccc(Cl)cc32)CC1,,C1COCCO1,CCOC(C)=O,Cl,,test
US20040138449A1,CNCC(O)c1ccc2c(c1)OCO2.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2sc(CCl)cc21>>CN(Cc1cc2c(s1)c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn2C)CC(O)c1ccc2c(c1)OCO2,,CN(C)C=O,O,CCN(C(C)C)C(C)C,,test
US20060166894A1,CC1(C)SCCCS1.O>>CC1(C)SCCCS1=O,,CO,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20090270363A1,COCCOCOC1CCCc2nc(-c3ccc(N(C)C)cc3CO)sc21>>COCCOCOC1CCCc2nc(-c3ccc(N(C)C)cc3C=O)sc21,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05591751,Cc1cc(C(=O)O)ccc1N.O=C(Cl)C=Cc1ccccc1>>Cc1cc(C(=O)O)ccc1NC(=O)C=Cc1ccccc1,,CC(C)=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20100168094A1,CC(C)(C)c1ccc(NC(=O)C2CNc3ccccc3S2)cc1O.OO>>CC(C)(C)c1ccc(NC(=O)C2CNc3ccccc3S2=O)cc1O,,CC(=O)O,CN(C)C=O,,,test
US20100261910A1,C#Cc1ccccc1.Cc1ccc(S(=O)(=O)Oc2cc(F)cc(Cl)c2)cc1>>Fc1cc(Cl)cc(C#Cc2ccccc2)c1,,CCCCCCC,,,,test
US20110190257A1,C[C@@H](CO)O[Si](C)(C)C(C)(C)C.O=C1c2ccccc2C(=O)N1O>>C[C@@H](CON1C(=O)c2ccccc2C1=O)O[Si](C)(C)C(C)(C)C,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05719151,N#C[O-].NC(=O)c1cccc(N)c1>>NC(=O)Nc1cccc(C(N)=O)c1,,CC(=O)O,,O,,test
US20010000513A1,NO.O=C(O)CCC(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1>>O=C(O)CCC(=NO)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1,,CCO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20110053904A1,COc1cc(C(F)(F)F)cc([N+](=O)[O-])c1C#N.OCc1ccccc1>>COc1cc(C(F)(F)F)cc(OCc2ccccc2)c1C#N,,C1COCCO1,O,[K+].[OH-],,test
US05639987,O=C(O)c1c(O)cccc1O.[Bi]>>O=C([O-])c1c(O)cccc1O.[Bi],,O,,,,test
US05510504,CCOP(=O)(C(Cc1ccccc1)N=C(c1ccccc1)c1ccccc1)C(Cc1ccccc1)N=C(c1ccccc1)c1ccccc1.Cl>>CCOP(=O)(C(N)Cc1ccccc1)C(N)Cc1ccccc1.Cl,,CCOCC,,,,test
US20160272624A1,CCOC(=O)CS.O=Cc1c(Cl)cccc1N1CCN(CCCCOc2ccc3ccc(=O)[nH]c3c2)CC1>>CCOC(=O)c1cc2c(N3CCN(CCCCOc4ccc5ccc(=O)[nH]c5c4)CC3)cccc2s1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US04254267,COC(=O)C=CC(=O)c1ccccn1>>O=C(O)C=CC(=O)c1ccccn1,,ClC(Cl)Cl,O,[Na+].[OH-],,test
US20020095036A1,CNC(=O)n1cnc(C(N)=O)c1N>>NC(=O)c1nc[nH]c1N,,CO,,CCN(CC)CC,,test
US20100234351A1,CC(C)(C)OC(=O)N(CCS(C)(=O)=O)C1CC1.Cl>>CS(=O)(=O)CCNC1CC1.Cl,,CCO,,,,test
US05639756,CC(C)(C)C(=O)CBr.OCCNc1nc2ccccc2[nH]1>>Br.CC(C)(C)C(=O)Cn1c(NCCO)nc2ccccc21,,CCCO,,,,test
US05081138,CCOC(=O)Cc1c(SC)c2cc(F)ccc2n1Cc1ccc(Cl)cc1>>CSc1c(CC(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(F)cc12,,C1CCOC1,,,,test
US20090281152A1,CC(C)Cn1cc(C=O)c2cc(Cl)ccc21.CCOC(=O)[C@@H](N)CS>>CCOC(=O)C1CSC(c2cn(CC(C)C)c3ccc(Cl)cc23)N1,,c1ccncc1,,Cl,,test
US20060025459A1,COC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1F>>COC(=O)c1cc([N+](=O)[O-])cc(N)c1F,[Fe],CC(=O)O,,Cc1ccccc1,,test
US20050214287A1,CN1CCCC1CCN.O=Cc1csc2ccccc12>>CN1CCCC1CCNCc1csc2ccccc12,,ClCCl,,[Na],,test
US20130261106A1,CC(C)Oc1cc(C2=CCN(C(=O)OC(C)(C)C)CC2)ccc1[N+](=O)[O-]>>CC(C)Oc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1N,[Pd],CO,,,,test
US20140349990A1,Cn1cc(C(Nc2cc(F)c(=O)n(C)c2)c2ccc(Cl)cc2)c(C(=O)O)n1>>Cn1cc2c(n1)C(=O)N(c1cc(F)c(=O)n(C)c1)C2c1ccc(Cl)cc1,,CCOCC,,,,test
US20020052408A1,O=C/C=C/c1ccc([N+](=O)[O-])cc1>>O=[N+]([O-])c1ccc(/C=C/CO)cc1,,CO,,[BH4-].[Na+],,test
US20080300266A1,C[Si](C)(C)C#Cc1ccc(N2CC[C@H](NCc3ccc(Cl)cc3Cl)C2)nc1>>C#Cc1ccc(N2CC[C@H](NCc3ccc(Cl)cc3Cl)C2)nc1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20090069336A1,CCOC(=O)c1cc2c(-c3ccc(Cl)cc3Cl)nc(N)nc2s1.NN>>NNC(=O)c1cc2c(-c3ccc(Cl)cc3Cl)nc(N)nc2s1,,CCO,,O,,test
US20150344468A1,CI.COCn1c(=O)sc2cc(CC(=O)OC(C)(C)C)ccc21>>COCn1c(=O)sc2cc(C(C)C(=O)OC(C)(C)C)ccc21,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20120065212A1,COC(=O)c1cnc(O[C@@H](C)C(F)(F)F)c(-c2ccc(Cl)cc2)n1>>C[C@H](Oc1ncc(C(=O)O)nc1-c1ccc(Cl)cc1)C(F)(F)F,,C1CCOC1,,O,[Li+].[OH-],test
US20020035137A1,CI.O=C(O)c1ccc([N+](=O)[O-])cc1Br>>COC(=O)c1ccc([N+](=O)[O-])cc1Br,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060211712A1,BrCc1ccccc1.COc1ccc(CN2C(=O)NC3(Cc4ccc([N+](=O)[O-])cc4C3)C2=O)cc1>>COc1ccc(CN2C(=O)N(Cc3ccccc3)C3(Cc4ccc([N+](=O)[O-])cc4C3)C2=O)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20090069333A1,CC(C)N.Fc1cc(F)c(-c2c(Cl)nc3cnncc3c2Cl)c(F)c1>>CC(C)Nc1c(-c2c(F)cc(F)cc2F)c(Cl)nc2cnncc12,,ClCCl,,,,test
US20090176778A1,C1CCOC1.CCO.Nc1nc(-c2ccccc2)cc(C(F)(F)F)c1[N+](=O)[O-]>>COC(=O)c1nc2c(C(F)(F)F)cc(-c3ccccc3)nc2[nH]1,[Pd],,,,,test
US20020052392A1,NN.O=C(O)CCC(=O)c1ccc(F)cc1>>O=C1CCC(c2ccc(F)cc2)=NN1,,CCO,,O,,test
US20130261178A1,NCCNC(=O)Nc1ccc(OCc2ccccc2)cc1>>NCCNC(=O)Nc1ccc(O)cc1,,Cl,,,,test
US20130109685A1,CCOC(=O)COc1ccc(Cl)cc1C1NCCc2ccccc21.COc1ccccc1CN=C=S>>COc1ccccc1CNC(=S)N1CCc2ccccc2C1c1cc(Cl)ccc1OCC(=O)O,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20110190264A1,CC(C)S(=O)(=O)c1ccccc1Nc1nc(S(C)(=O)=O)nc2ccnn12.Cc1cc(N)c(OC(C)C)cc1C1CCN(C)CC1>>Cc1cc(Nc2nc(Nc3ccccc3S(=O)(=O)C(C)C)n3nccc3n2)c(OC(C)C)cc1C1CCN(C)CC1,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090186930A1,CC(C)(C)O.Nc1ccc(Oc2ccc(-c3c[nH]c(COc4ccccc4)n3)cc2)cc1F.O=C=NS(=O)(=O)Cl>>CC(C)(C)OC(=O)NS(=O)(=O)Nc1ccc(Oc2ccc(-c3c[nH]c(COc4ccccc4)n3)cc2)cc1F,,ClCCl,,CCN(CC)CC,,test
US20140243368A1,C#CC1CCCCN1.Cc1nc(C(=O)Cl)c(-c2ccccc2)s1>>C#CC1CCCCN1C(=O)c1nc(C)sc1-c1ccccc1,,CCOC(C)=O,Cc1ccccc1,Cl,[Na+].[OH-],test
US20130079324A1,CC(C)(C)[Si](C)(C)OCC=O.CCC(CC)(C(=O)[O-])P(=O)(O)OC.CCN(C(C)C)C(C)C>>CCOC(=O)/C=C/CO[Si](C)(C)C(C)(C)C,,CC#N,,[Cl-].[Li+],,test
US06323235B1,COC(=O)COc1cccc2c(CCBr)c(C)oc12.ON=C(c1ccccc1)c1ccccc1>>COC(=O)COc1cccc2c(CCON=C(c3ccccc3)c3ccccc3)c(C)oc12,,CN(C)C=O,O,CC(=O)O,[H-].[Na+],test
US20110263647A1,CC(C)(C)OC(=O)N[C@H](CNc1ncc(-c2ccc3cnc(F)cc3c2)s1)Cn1cnc(C(F)(F)F)c1>>N[C@H](CNc1ncc(-c2ccc3cnc(F)cc3c2)s1)Cn1cnc(C(F)(F)F)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150376181A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1NC2(CNC2)n2c1c(Cl)cc(Br)c2=O>>CC(C)(C)OC(=O)N1CC2(C1)NC(=O)c1c(Cl)cc(Br)c(=O)n12,,C1COCCO1,,O,[Na+].[OH-],test
US04081450,C=[N+]=[N-].CC1=[N+](C)CCC1(C)c1ccccc1.F[B-](F)(F)F>>CC1(c2ccccc2)CC[N+]2(C)CC12C.F[B-](F)(F)F,,CCOCC,,ClCCl,,test
US20010021718A1,CC(C)(C)OC(=O)C[C@@H](CCCC1CCCCC1)c1nc(C(=O)N2CC(N3CCOCC3)C2)no1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C(O)C[C@@H](CCCC1CCCCC1)c1nc(C(=O)N2CC(N3CCOCC3)C2)no1,,ClCCl,,,,test
US20060035897A1,Brc1ccc2cnncc2c1.Cc1ccc(C(=O)Nc2ccc(CN3CCOCC3)c(C(F)(F)F)c2)cc1Br>>Cc1ccc(C(=O)Nc2ccc(CN3CCOCC3)c(C(F)(F)F)c2)cc1-c1ccc2cnncc2c1,,CCO,CCOC(C)=O,,,test
US20040186103A1,CC(C)C(=O)Cl.Nc1cc(Br)c(F)cc1F>>CC(C)C(=O)Nc1cc(Br)c(F)cc1F,,C1CCOC1,,CCN(CC)CC,,test
US20060205715A1,CC1(C)CC(=O)c2ccc(O)cc21.N#Cc1ccc(Cl)nc1>>CC1(C)CC(=O)c2ccc(Oc3ccc(C#N)cn3)cc21,,CS(C)=O,,[H-].[Na+],,test
US20090143361A1,COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)cc(Cl)c4)n3c2n1.OB(O)c1cccc(OC(F)(F)F)c1>>COc1ccc2nc(C)c3c(C)nc(-c4cccc(OC(F)(F)F)c4)n3c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20050038071A1,CCCC=C[C@H]1CCC[C@H](C)N1C(=O)OC(C)(C)C>>CCCC=C[C@H]1CCC[C@H](C)N1,,ClCCl,O=C(O)C(F)(F)F,,,test
US05025025,COC(=O)CCCC(CCCNS(=O)(=O)c1ccc(Cl)cc1)CCc1cccnc1>>O=C(O)CCCC(CCCNS(=O)(=O)c1ccc(Cl)cc1)CCc1cccnc1,,C1COCCO1,,[Na+].[OH-],,test
US05482974,CC(C)(C)[O-].N#Cc1c(F)cccc1Cl>>CC(C)(C)Oc1cccc(Cl)c1C#N,,COCCOC,,O,,test
US04507297,CCOC(=O)[C@@H]1O[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N1CCN(Cc2ccc(OC)c(OC)c2OC)CC1.O=C(O)C(=O)O>>CCOC(=O)[C@@H]1O[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N1CCN(Cc2ccc(OC)c(OC)c2OC)CC1.O=C(O)C(=O)O,,CC(C)=O,,O,O,test
US20070265242A1,CC(C)(C)C(=O)OCI.C[C@@H](O)[C@H]1C(=O)N2C(C(=O)[O-])=C(c3ccc4c(c3)CC(=O)N4)C[C@H]12>>C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCOC(=O)C(C)(C)C)=C(c3ccc4c(c3)CC(=O)N4)C[C@H]12,,CN(C)C=O,,CCOC(C)=O,,test
US06960586B2,Cc1c(O)ccc2cc(C(=O)c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)ccc12.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1c(OS(=O)(=O)C(F)(F)F)ccc2cc(C(=O)c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)ccc12,,O,c1ccncc1,,,test
US20090239845A1,BrCc1ccccc1.CCOC(=O)c1cc(C)n(Cc2cc(Cl)ccc2O)n1>>CCOC(=O)c1cc(C)n(Cc2cc(Cl)ccc2OCc2ccccc2)n1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100234376A1,CCCC[Sn](Cl)(CCCC)CCCC.CSc1cc(I)ncn1>>CCCC[Sn](CCCC)(CCCC)c1cc(SC)ncn1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20110319378A1,CC[C@@H](CO)N1C(=O)[C@@](C)(CC(=O)OC)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1.SCc1ccccc1>>CC[C@@H](CSCc1ccccc1)N1C(=O)[C@@](C)(CC(=O)OC)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1,,Cc1ccccc1,,CCCCP(=CC#N)(CCCC)CCCC,,test
US20090124625A1,C#CCCC(=O)O.CNc1cccc(Cl)c1>>C#CCCC(=O)N(C)c1cccc(Cl)c1,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20100056516A1,COC(=O)c1ccc(C(=O)OC)c(-c2cccnc2)c1>>COC(=O)c1ccc(C(=O)O)cc1-c1cccnc1,,CO,,[Na+].[OH-],,test
US20030045558A1,CCCc1c(OCCc2nc(-c3ccc(-c4ccccc4)cc3)oc2C)cccc1OC(C)(C)C(=O)OCC>>CCCc1c(OCCc2nc(-c3ccc(-c4ccccc4)cc3)oc2C)cccc1OC(C)(C)C(=O)O,,C1CCOC1,CCO,[Na+].[OH-],,test
US20120309966A1,CN1CCNCC1.O=C1CCC(C(=O)NCc2nccnc2Cl)CC1>>CN1CCN([C@@H]2CC[C@@H](C(=O)NCc3nccnc3Cl)CC2)CC1,,CC(=O)O,ClCCl,[BH3-]C#N.[Na+],,test
US20130085144A1,N#Cc1nc(Cl)ccc1[N+](=O)[O-].Sc1cc(Cl)cc(Cl)c1>>N#Cc1nc(Sc2cc(Cl)cc(Cl)c2)ccc1[N+](=O)[O-],,CC#N,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120053173A1,CNc1cc(OC)ccc1[N+](=O)[O-].CO>>COc1ccc2ncn(C)c2c1,[Pd],,,,,test
US04634704,CN=C=S.Fc1ccc(Cn2c(NC3CCN(CCNc4nccs4)CC3)nc3ccccc32)cc1>>CNC(=S)N(CCN1CCC(Nc2nc3ccccc3n2Cc2ccc(F)cc2)CC1)c1nccs1,,C1CCOC1,,,,test
US20120015962A1,O=C(Nc1cc(Cl)ccc1N1CCC(NC(=O)C(F)(F)F)C1)c1cnn2cccnc12>>NC1CCN(c2ccc(Cl)cc2NC(=O)c2cnn3cccnc23)C1,,CCOC(C)=O,,CO,[Na+].[OH-],test
US20090054453A1,BrBr.COc1cccc2c1C[C@@H](NC(=O)C(F)(F)F)CC2>>COc1ccc(Br)c2c1C[C@@H](NC(=O)C(F)(F)F)CC2,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20140275087A1,CCCn1cc(C[C@@H]2C(=O)N(Cc3ccccc3)C[C@H]2c2ccccc2)nn1>>CCCn1cc(C[C@@H]2CN(Cc3ccccc3)C[C@H]2c2ccccc2)nn1,,C1CCOC1,,[Li],,test
US20150322090A1,C(=C/c1nc2c(ccc3ncccc32)[nH]1)\c1ccc2ccccc2n1.COS(=O)(=O)c1ccc(C)cc1>>Cn1c(/C=C/c2ccc3ccccc3n2)nc2c3cccnc3ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20080287409A1,CCOC(=O)C(Cl)C(=O)CCCOCc1ccccc1.NC(=S)c1ccc(C(F)(F)F)cc1>>CCOC(=O)c1sc(-c2ccc(C(F)(F)F)cc2)nc1CCCOCc1ccccc1,,CCO,,,,test
US05116833,CSc1ccncc1.O=C1CCC(=O)N1Cl>>ClCSc1ccncc1,,c1ccccc1,,c1ccncc1,,test
US04267180,CCOC=C(C(=O)OCC)C(=O)OCC.N=C(N)c1ccc(N)cc1>>Nc1ccc(-c2ncc(C(=O)O)c(O)n2)cc1,,CCO,,[Na],,test
US20150284394A1,CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccc(C(C)(C)C)cc2)CC1>>CC(C)(C)c1ccc(C(=O)NCC2CCNCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070099901A1,COC(CCCN)OC.O=[N+]([O-])c1cnc2cc(Br)ccc2c1Cl>>COC(CCCNc1nc2cc(Br)ccc2cc1[N+](=O)[O-])OC,,ClC(Cl)Cl,O,CCN(CC)CC,O=C([O-])[O-].[K+].[K+],test
US05633392,CC(=O)OC(C)=O.C[C@@]12C=CC[C@H]1C1=CCc3cc(O)ccc3[C@H]1CC2>>CC(=O)Oc1ccc2c(c1)CC=C1[C@@H]3CC=C[C@@]3(C)CC[C@@H]12,,CCOC(C)=O,,c1ccncc1,,test
US20030109579A1,COC(=O)Cc1ccc(OCC#Cc2cccc(C#CCOc3ccc(CC(=O)OC)cc3)c2)cc1>>COC(=O)Cc1ccc(OCC#Cc2cccc(C#CCOc3ccc(CC(=O)O)cc3)c2)cc1,,CCO,,Cl,[Na+].[OH-],test
US04408077,Cc1ccccc1CCC(=NO)C(=O)C(F)(F)F>>Cc1cccc2c1CCC(=NO)C2(O)C(F)(F)F,,Cc1ccccc1,,O=S(=O)(O)O,,test
US05854273,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=C1Cc2ccccc2O1>>COC(=O)Cc1coc2ccccc12,,Cc1ccc(C)cc1,,,,test
US04033996,CCCCCC(CCCNS(C)(=O)=O)OC1CCCCO1.CCOC(=O)C(C)CCCCCBr>>CCCCCC(CCCN(CCCCCC(C)C(=O)OCC)S(C)(=O)=O)OC1CCCCO1,,O,c1ccccc1,CN(C)C=O,[H-].[Na+],test
US20020028834A1,Nc1ccc2c(CCC3CCN(Cc4ccccc4)CC3)noc2c1.O=S(=O)(Cl)c1ccccc1>>Cc1noc2ccccc12.NS(=O)(=O)c1ccccc1,,ClCCl,,c1ccncc1,O=C([O-])O.[Na+],test
US20130005574A1,CCOC(=O)C1=C(Br)/C(=N/OS(C)(=O)=O)CC(c2ccc(Cl)cc2F)N1.OCC(F)(F)F>>CCOC(=O)c1nc(-c2ccc(Cl)cc2F)cc(N)c1OCC(F)(F)F,,CCOCC,,O=C([O-])[O-].[K+].[K+],,test
US20090291917A1,O=Cc1cc(O)ccc1Br>>OCc1cc(O)ccc1Br,,CO,,[BH4-].[Na+],,test
US04210659,Cc1cccc(Cl)c1N1CC(O)N2CCN=C12>>Cc1cccc(Cl)c1N1C=CN2CCN=C21,,Cl,,,,test
US20100256097A1,O=C(CCl)OCCN(CCO)C(=O)CCl>>O=C(CCl)OCCN1CCOCC1=O,,C1CCOC1,,[H-].[Na+],,test
US20150218150A1,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.CN1Cc2cc(-c3ccc(I)s3)ccc2C1=O>>CN1Cc2cc(-c3ccc(-c4ccc(N)nc4)s3)ccc2C1=O,,CO,ClCCl,,,test
US06037495,CC(=O)OCc1ccccc1C(=NO)C(N)=O>>CC(=O)OCc1ccccc1/C(=N\O)C(N)=O,,C1COCCO1,Cl,O=C([O-])O.[Na+],,test
US05428041,C1CCNCC1.CCCCCCC(=O)N(C)C1NC(c2ccc(F)cc2)=NC1(C(F)(F)F)C(F)(F)F.CS(C)=O.Cl>>CCCCCCC(=O)N(C)C1N(C)C(c2ccc(N3CCCCC3)cc2)=NC1(C(F)(F)F)C(F)(F)F.Cl,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110319618A1,C#Cc1ccc(C(F)(F)F)cc1.Cc1nc(C)c(I)c(=O)[nH]1.O=P(Cl)(Cl)Cl>>Cc1nc(C)c(C#Cc2ccc(C(F)(F)F)cc2)c(Cl)n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,,CCN(CC)CC,,test
US20060069140A1,COC(=O)c1ccc(C(=O)NNC(C)=C2C(=O)N(c3ccc(C(C)(C)C)cc3)N=C2C)s1>>CC1=NN(c2ccc(C(C)(C)C)cc2)C(=O)C1=C(C)NNC(=O)c1ccc(C(=O)O)s1,,CO,,Cl,[Na+].[OH-],test
US04177197,BrCCCCBr.c1ccoc1>>BrCCCCc1ccco1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US07074801B1,CSc1ccc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2-c2ccc3ncc(I)n3c2)cc1.O=S([O-])OO>>CS(=O)(=O)c1ccc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2-c2ccc3ncc(I)n3c2)cc1,,C1CCOC1,CO,O,,test
US04336389,CCOC(=O)c1sc(Cl)nc1-c1ccccc1>>O=C(O)c1sc(Cl)nc1-c1ccccc1,,C1CCOC1,,O,[Na+].[OH-],test
US20130059834A1,CC(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3n[nH]c4cc(Cl)ccc34)nc12.CCI>>CCn1nc(-c2cnc3c(n2)c(C(=O)NC(C)C)cn3COCC[Si](C)(C)C)c2ccc(Cl)cc21,,CN(C)C=O,O,[H-].[Na+],,test
US20100004239A1,CCOC(=O)Cc1[nH]c(C(=O)OC(C)(C)C)c(C)c1C(=O)OCC>>CCOC(=O)c1c(CC(=O)O)[nH]c(C(=O)OC(C)(C)C)c1C,,C1CCOC1,,CO,[Li+].[OH-],test
US20160272626A1,COC(=O)c1cnc(N2CC(F)(F)C2)cn1>>O=C(O)c1cnc(N2CC(F)(F)C2)cn1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20080207648A1,N#Cc1ccc(N)cn1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>N#Cc1ccc(NC(=O)Oc2ccc([N+](=O)[O-])cc2)cn1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US05276025,CON(C)C(=O)c1cc(S(N)(=O)=O)sc1Cl.[Li]C>>CC(=O)c1cc(S(N)(=O)=O)sc1Cl,,C1CCOC1,,CCOCC,,test
US20150031676A1,CC(C)(C)OC(=O)N1CCN(Cc2cc(Br)c3c(N)ncnn23)CC1.COc1cccc2cc(B(O)O)sc12>>COc1cccc2cc(-c3cc(CN4CCN(C(=O)OC(C)(C)C)CC4)n4ncnc(N)c34)sc12,,COCCOC,O,CCOC(C)=O,O=C([O-])O.[Na+],test
US20150225404A1,C=C1CCc2c(-c3cncnc3)cc(OCc3ccccn3)nc21>>CC1CCc2c(-c3cncnc3)cc(OCc3ccccn3)nc21,,CO,,,,test
US20100197674A1,CCOC(=O)c1nc2ccccc2n(-c2cccc(C)n2)c1=O>>Cc1cccc(-n2c(=O)c(C(=O)O)nc3ccccc32)n1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20140315888A1,COC(OC)OC.Cc1cnc2nc(NN)c(Cl)nc2c1>>Cc1cnc2c(c1)nc(Cl)c1nncn12,,CCOCC,,,,test
US20080242704A1,Cc1ccc(N)cc1Nc1ncc(-c2ccc(C#N)cc2)o1.O=C(CBr)c1ccc(F)cc1>>Cc1ccc(NCC(=O)c2ccc(F)cc2)cc1Nc1ncc(-c2ccc(C#N)cc2)o1,,CC(=O)N(C)C,,O=C([O-])O.[Na+],,test
US20160272596A1,COc1ccc2ccccc2c1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)CN(C(=O)c2ccc([N+](=O)[O-])cc2)c2ccccc21>>COc1ccc2ccccc2c1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)CN(C(=O)c2ccc(N)cc2)c2ccccc21,[Pd],CO,,,,test
US20120101134A1,CCc1c(Cl)cccc1OC(=O)N(CC)CC>>CCc1c(O)cccc1Cl,,CCO,,[Na+].[OH-],,test
US04654362,CCOC(=O)C1CCc2cc(O)ccc2O1.ClCc1ccccc1>>CCOC(=O)C1CCc2cc(OCc3ccccc3)ccc2O1,,CN(C)C=O,,[H-].[Na+],,test
US20080194549A1,COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CNC2CC2)C(C)C)ccc1OC.O=C(Cl)N1CCCC1>>COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN(C(=O)N2CCCC2)C2CC2)C(C)C)ccc1OC,,ClCCl,,CCN(CC)CC,,test
US20120083488A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.CC1(C)c2cc(OS(=O)(=O)C(F)(F)F)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21>>CC(C)(C)OC(=O)N1CC=C(c2ccc3c(c2)C(C)(C)c2[nH]c4cc(C#N)ccc4c2C3=O)CC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US04016280,CCC(C)N1CCC(O)(c2ccccc2)C(C(=O)c2ccccc2)C1>>CCC(C)N1CCC(c2ccccc2)(c2ccccc2)CC1,,c1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20150111866A1,COC(=O)c1ccc(-c2cnc(OC)c(-c3cnc(N4CC(F)C4)nc3CN3C(=O)O[C@H](c4cc(F)cc(F)c4)[C@@H]3C)c2)c(C)c1>>COc1ncc(-c2ccc(C(=O)O)cc2C)cc1-c1cnc(N2CC(F)C2)nc1CN1C(=O)O[C@H](c2cc(F)cc(F)c2)[C@@H]1C,,C1COCCO1,,[Li+].[OH-],,test
US06900227B2,COC(=O)c1cc(Br)c2c(c1Cl)OC(c1ccccc1)(c1ccccc1)O2>>O=C(O)c1cc(Br)c2c(c1Cl)OC(c1ccccc1)(c1ccccc1)O2,,C1CCOC1,O,CO,[Li+].[OH-],test
US20080161351A1,CCOC(=O)COc1ccc(Sc2ccc(COc3ccc(C(F)(F)F)cc3)cc2Cl)cc1C>>Cc1cc(Sc2ccc(COc3ccc(C(F)(F)F)cc3)cc2Cl)ccc1OCC(=O)O,,CCO,,Cl,[Na+].[OH-],test
US04717724,COc1ccc(CCC(=O)Cl)cc1.Oc1ccc2c(c1)CCNC2>>COc1ccc(CCCN2CCc3cc(O)ccc3C2)cc1,,ClCCl,,CCN(CC)CC,,test
US20050107371A1,CC(C)(C)OC(=O)C1COc2cc(O)ccc2C1.Cc1oc(-c2ccc(Br)cc2)nc1CCl>>Cc1oc(-c2ccc(Br)cc2)nc1COc1ccc2c(c1)OCC(C(=O)OC(C)(C)C)C2,,O,,O=C([O-])[O-].[K+].[K+],,test
US20080021056A1,C[Si](C)(C)CCOCn1cc(C=O)c(I)n1.OB(O)c1cc(F)ccc1Br>>C[Si](C)(C)CCOCn1cc(C=O)c(-c2cc(F)ccc2Br)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20100113462A1,CCOC(=O)C1(N(C)C(=O)c2cccc(C)c2OC(C)C)Cc2ccccc2C1>>Cc1cccc(C(=O)N(C)C2(C(=O)O)Cc3ccccc3C2)c1OC(C)C,,CCO,,O,[K+].[OH-],test
US05948792,CC(C)(C)[C@H]1OC(=O)[C@](c2ccccc2)([C@H]2CCC(=O)C2)O1>>O=C(O)[C@](O)(c1ccccc1)[C@H]1CCC(O)C1,,CCOCC,CO,[BH4-].[Na+],,test
US20160264536A1,CC(C)(C)[Si](OC1CC(Br)C(Br)C1)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](OC1CC=C(Br)C1)(c1ccccc1)c1ccccc1,,C1CCOC1,,O,CC(C)(C)[O-].[K+],test
US20150225449A1,COc1ccc2c(Br)cccc2c1CCl.C[C@@H](C(=O)N[C@@H]1C(=O)Nc2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C)N(C)C(=O)OC(C)(C)C>>COc1ccc2c(Br)cccc2c1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)[C@H](C)N(C(=O)CS(C)(=O)=O)c2ccccc21,,CCOC(C)=O,CN(C)C=O,[I-].[Na+],O=C([O-])[O-].[Cs+].[Cs+],test
US20070197478A1,Cc1nc(Cl)c([N+](=O)[O-])c(Cl)c1C.NCc1ccccc1>>Cc1nc(Cl)c([N+](=O)[O-])c(NCc2ccccc2)c1C,,CC#N,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US04025528,Brc1nccs1.CCOC(=O)C(C)c1ccc(S)cc1>>CC(C(=O)O)c1ccc(Sc2nccs2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US08129361B2,Cc1c(Cl)cccc1CCCO.O=C1CCC(=O)N1Br>>Cc1c(Cl)cccc1CCCBr,,ClCCl,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020091265A1,CCOC(=O)C1CCN(c2cc(-c3ccccc3C)c(C(=O)N(C)Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)cn2)CC1>>Cc1ccccc1-c1cc(N2CCC(C(=O)O)CC2)ncc1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1,,CO,,[Na+].[OH-],,test
US20110009394A1,Cl.Cl.NC1CCN(C[C@@H]2CCn3c(=O)cnc4ccc(=O)n2c43)CC1.O=Cc1ccc2c(c1)OCCO2>>Cl.Cl.O=c1cnc2ccc(=O)n3c2n1CC[C@H]3CN1CCC(NCc2ccc3c(c2)OCCO3)CC1,,CO,,O=C([O-])O.[Na+],,test
US04115398,Cc1ccc(C=CCCl)cc1.Cl.c1ccc2c(c1)CNC2>>Cc1ccc(C=CCN2Cc3ccccc3C2)cc1.Cl,,CCO,,,,test
US05648381,NNC(=O)Nc1ccccc1.O=c1c(=NO)c(=O)c2ccccc12>>O=C(NN=c1c(=NO)c(=O)c2ccccc12)Nc1ccccc1,,CCO,O,Cl,,test
US20110183998A1,COC(=O)C(Oc1ccc(OCc2ccccc2)cc1)C(=O)OC>>OCC(CO)Oc1ccc(OCc2ccccc2)cc1,,Cc1ccccc1,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20150225441A1,CC(=O)O[C@@H]1[C@H](n2ccc(N)nc2=O)O[C@@](COCc2ccccc2)(C(F)F)[C@H]1OCc1ccccc1>>Nc1ccn([C@@H]2O[C@@](COCc3ccccc3)(C(F)F)[C@@H](OCc3ccccc3)[C@@H]2O)c(=O)n1,,N,,CO,,test
US20130116245A1,COC(=O)c1cc2ccccn2c1>>COC(=O)c1cc2n(c1)CCCC2,[Pd],CO,,,,test
US20110118251A1,COC(=O)c1cccnc1F.Cc1n[nH]cc1C=O>>COC(=O)c1cccnc1-n1cc(C=O)c(C)n1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150336979A1,O=C[C@H]1CO[C@@H]2[C@@H](N(Cc3ccccc3)C(=O)NC3CCCCC3)CO[C@H]12>>O=C(NC1CCCCC1)N(Cc1ccccc1)[C@H]1CO[C@@H]2[C@@H](CO)CO[C@H]12,,CCO,,[BH4-].[Na+],,test
US20120295924A1,C=CCB1OC(C)(C)C(C)(C)O1.CCOC(=O)c1sc2c(c1Br)c(=O)n(C)c(=O)n2C>>C=CCc1c(C(=O)OCC)sc2c1c(=O)n(C)c(=O)n2C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110021625A1,COc1cc2c(cc1O[Si](C(C)C)(C(C)C)C(C)C)CC2(C#N)CCC(O)c1ccoc1>>COc1cc2c(cc1O[Si](C(C)C)(C(C)C)C(C)C)CC2(C#N)CCC(=O)c1ccoc1,,O,,CCN(CC)CC,CS(C)=O,test
US20010016579A1,CN1CCCN(c2nc3cc(Cl)c([N+](=O)[O-])cc3o2)CC1>>CN1CCCN(c2nc3cc(Cl)c(N)cc3o2)CC1,[Pd],CO,,Cl,[H][H],test
US05237063,Fc1cc(OC(F)(F)F)nc(F)n1.N>>Nc1nc(F)cc(OC(F)(F)F)n1,,CCOCC,,,,test
US20050182053A1,CC(C)(C)OC(=O)N1CCC(N)CC1.c1cc(OCC2CO2)ccn1>>CC(C)(C)OC(=O)N1CCC(NCC(O)COc2ccncc2)CC1,,CN(C)C=O,,,,test
US20040023947A1,CCOC(=O)C1=CN(C(=O)c2ccc(F)cc2)CC(C)(C)c2c1[nH]c1cc(O)ccc21.ClCCN1CCOCC1>>CCOC(=O)C1=CN(C(=O)c2ccc(F)cc2)CC(C)(C)c2c1[nH]c1cc(OCCN3CCOCC3)ccc21,,CC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20130116277A1,COc1ccc2c(=O)n(-c3ccc(C(F)(F)F)cc3)cc(Br)c2c1.OB(O)c1ccc(C(F)(F)F)cc1>>COc1ccc2c(=O)n(-c3ccc(C(F)(F)F)cc3)cc(-c3ccc(C(F)(F)F)cc3)c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20150344466A1,CCOC(=O)c1cc(Cc2ccc(F)cc2)on1>>O=C(O)c1cc(Cc2ccc(F)cc2)on1,,O,,CCO,[Na+].[OH-],test
US20030225270A1,N#CC1(NC(=O)C(CC2CCCCC2)NC(=O)N2CCOCC2)CCNCC1.O=C(O)CCCBr>>N#CC1(NC(=O)C(CC2CCCCC2)NC(=O)N2CCOCC2)CCN(CCCC(=O)O)CC1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US04229449,CI.COc1ccccc1OC(c1ccccc1)C(O)C#N>>COc1ccccc1OC(c1ccccc1)C(C#N)OC,,CN(C)C=O,O,[H-].[Na+],,test
US05185370,CC(=O)Nc1ccc(C=O)cc1.O=C(CC(=O)C1CC1)C1CC1>>CC(=O)Nc1ccc(C=C(C(=O)C2CC2)C(=O)C2CC2)cc1,,Cc1ccccc1,,C1CCNCC1,CC(=O)O,test
US20150038488A1,COc1ccc([C@@H](C)N2C[C@H]([C@@H](C)Oc3cc(Br)cn4ncc(/C=N/O)c34)CC2=O)cc1>>COc1ccc([C@@H](C)N2C[C@H]([C@@H](C)Oc3cc(Br)cn4ncc(C#N)c34)CC2=O)cc1,,CC(=O)OC(C)=O,,,,test
US20070066618A1,Cc1ccc(S(=O)(=O)N=C=O)cc1.O=[N+]([O-])c1cc(C(F)(F)F)c(Cl)cc1Nc1ccc(CCO)cc1>>Cc1ccc(S(=O)(=O)NC(=O)OCCc2ccc(Nc3cc(Cl)c(C(F)(F)F)cc3[N+](=O)[O-])cc2)cc1,,ClCCl,,,,test
US20120040948A1,BrCCCBr.Cn1cnc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2ccccc2)C(N)C3)c1>>Cn1cnc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2ccccc2)C(N2CCC2)C3)c1,O,ClCCl,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20130059853A1,COc1ccc(-c2ccc3c(c2)COC3=O)c(O)c1OC(F)F.NC(=O)c1ccc(CBr)cc1>>COc1ccc(-c2ccc3c(c2)COC3=O)c(OCc2ccc(C(N)=O)cc2)c1OC(F)F,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100216769A1,CI.O=C(N1CCc2cc(O)c([N+](=O)[O-])cc2CC1)C(F)(F)F>>COc1cc2c(cc1[N+](=O)[O-])CCN(C(=O)C(F)(F)F)CC2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110275657A1,CCCOC1(C2CCCCC2C)CN(C(=O)OC(C)(C)C)C1.O=C(O)C(F)(F)F>>CCCOC1(C2CCCCC2C)CNC1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20160060273A1,CCI.COC(=O)c1cc(O)c(I)c(C2CC2)c1>>CCOc1cc(C(=O)OC)cc(C2CC2)c1I,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20040106606A1,CC(C)(C)O.Cc1cc(O)ccc1CC(=O)O>>Cc1cc(O)c(C(C)(C)C)cc1CC(=O)O,,O,,O=S(=O)(O)O,,test
US20150080383A1,O=C(/C=C/c1cn2ccccc2n1)c1cc(Br)ccc1O>>O=c1cc(-c2cn3ccccc3n2)oc2ccc(Br)cc12,,CS(C)=O,,II,,test
US04910306,C[Si](C)(C)Br.Nc1c(F)cccc1F>>C[Si](C)(C)Nc1c(F)cccc1F,,c1ccccc1,,,,test
US20150315188A1,CC1(c2cccnc2)CO1.Cc1cc(F)c2[nH]c3c(c2c1)CN1CCCC1C3>>Cc1cc(F)c2c(c1)c1c(n2CC(C)(O)c2cccnc2)CC2CCCN2C1,,CN(C)C=O,,[H-].[Na+],,test
US20060040957A1,Cc1c(=O)[nH]c(=O)n2cc(C(=O)NCc3ccncc3)sc12.O=S(=O)(c1ccc(Cl)cc1CCCl)c1ccc(Cl)cc1CCCl>>Cc1c(=O)n(CCS(=O)(=O)c2ccc(Cl)cc2)c(=O)n2cc(C(=O)NCc3ccncc3)sc12.Cl,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100184719A1,CC1(CCl)CNC(=O)O1.Clc1ccc(Br)nc1>>CC1(CCl)CN(c2ccc(Cl)cn2)C(=O)O1,,C1COCCO1,,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20100286215A1,COS(=O)(=O)OC.O=C(O)c1cc(I)ccc1F>>COC(=O)c1cc(I)ccc1F,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04234588,CN(C)Cc1ccc(CSCCN)o1.O=c1[nH]c(N[N+](=O)[O-])ncc1Cc1cccnc1>>CN(C)Cc1ccc(CSCCNc2ncc(Cc3cccnc3)c(=O)[nH]2)o1,,CCO,,,,test
US05009701,CCCCCCNC.CCOC(C)=O.O=[N+]([O-])c1ccc(Cl)c(C=CCCl)c1>>CCCCCCN(C)C(=O)C=Cc1cc([N+](=O)[O-])ccc1Cl,,CCOC(C)=O,,C1CCOC1,,test
US20050032786A1,C1COCCN1.N#Cc1ccnc(Cl)c1>>N#Cc1ccnc(N2CCOCC2)c1,,CN1CCCC1=O,,O,,test
US20140080788A1,CCOC(=O)CCCOc1cccc(C)c1C>>Cc1cccc(OCCCC(=O)O)c1C,,C1COCCO1,,Cl,[Li+].[OH-],test
US20070191333A1,CC(c1ccccc1)N1CCC(CNC(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)NCC1CCNC1,[Pd],CO,,,,test
US04146716,CC(C)Nc1ncnc2sccc12.O=[N+]([O-])O>>CC(C)Nc1ncnc2sc([N+](=O)[O-])cc12,,O=S(=O)(O)O,,O=C([O-])[O-].[Na+].[Na+],,test
US20160244441A1,FCCCBr.Oc1ccc(-c2cn3ccc(N4CCC4)cc3n2)cc1>>FCCCOc1ccc(-c2cn3ccc(N4CCC4)cc3n2)cc1,,ClCCl,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20150238473A1,CC(=O)O[C@H](CCCCl)c1ccc(C(C)(C)C)cc1.OC(c1ccccc1)(c1ccccc1)C1CCNCC1>>CC(=O)O[C@H](CCCN1CCC(C(O)(c2ccccc2)c2ccccc2)CC1)c1ccc(C(C)(C)C)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130303518A1,CCN(CC)CCN1CCCCc2[nH]c(C=O)c(C)c2C1=O.O=C1Cc2cc(F)ccc2N1>>CCN(CC)CCN1CCCCc2[nH]c(/C=C3\C(=O)Nc4ccc(F)cc43)c(C)c2C1=O,,CCO,,C1CCNCC1,,test
US04511504,CC(C)C[C@H](N)C(=O)OCc1ccccc1.CCOC(=O)C(C)Br>>CCOC(=O)[C@@H](C)N[C@@H](CC(C)C)C(=O)OCc1ccccc1,,CC#N,,CN1CCOCC1,,test
US20140371199A1,COc1cc(-c2ccc3ncc(-c4ccc(C#N)cc4)n3c2)ccc1C(=O)N1CCN(C(=O)OC(C)(C)C)CC1>>N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)N5CCNCC5)c(O)c4)cn23)cc1,,ClCCl,,BrB(Br)Br,,test
US05304563,BrC1CCCCCCC1.COC(=O)Cc1ccc(OCc2ccc3ccccc3n2)c(OC)c1>>COC(=O)C(c1ccc(OCc2ccc3ccccc3n2)c(OC)c1)C1CCCCCCC1,,CN(C)C=O,CN(C)C=O,Cl,CC(C)(C)[O-].[K+],test
US05494925,CCCC(NS(=O)(=O)NC(=O)OCc1ccccc1)C(=O)O.CO>>CCCC(NS(=O)(=O)NC(=O)OCc1ccccc1)C(=O)OC,[Pd],,,,,test
US05219871,BrCCc1ccc2c(c1)CCO2.CN>>CNCCc1ccc2c(c1)CCO2,,CO,,,,test
US20070276000A1,COCOc1c(Br)c(C)cc2cc(OC)ccc12.OB(O)c1cccc(C(F)(F)F)c1>>COCOc1c(-c2cccc(C(F)(F)F)c2)c(C)cc2cc(OC)ccc12,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US04133809,O=C(NCc1nnc2n1-c1ccc(Cl)cc1N(c1ccccc1)C(=O)C2)OCc1ccccc1>>NCc1nnc2n1-c1ccc(Cl)cc1N(c1ccccc1)C(=O)C2,,CC(=O)O,,Br,,test
US05288735,Br.Cn1nc(S(N)(=O)=O)sc1=NC(=O)CNC(=O)OCc1ccccc1>>Br.Cn1nc(S(N)(=O)=O)sc1=NC(=O)CN,,CC(=O)O,,CCOCC,,test
US20010046993A1,CCOC(=O)C1(CCN2CCN(Cc3ccccc3)CC2)CCCC1>>O=C(O)C1(CCN2CCN(Cc3ccccc3)CC2)CCCC1,,CO,O,Cl,[K+].[OH-],test
US20090143402A1,CC[C@H](Nc1oc(=O)c2ccccc2c1C(C)=O)c1ccccc1.Nc1ccc(Cl)c(Cl)c1>>CC[C@H](NC(=O)c1c(C)n(-c2ccc(Cl)c(Cl)c2)c(=O)c2ccccc12)c1ccccc1,,CC#N,,,,test
US20140249130A1,CCOC(=O)Cc1cccc(-c2cnn(C3CCCCO3)c2)c1>>CCOC(=O)Cc1cccc(-c2cn[nH]c2)c1,,CO,Cl,,,test
US06706763B1,COC(=O)C(Cc1ccc(OC)c(C(=O)NCc2ccc(C(F)(F)F)cc2)c1)SC.O=C(OO)c1cccc(Cl)c1>>COC(=O)C(Cc1ccc(OC)c(C(=O)NCc2ccc(C(F)(F)F)cc2)c1)S(C)=O,,ClCCl,,,,test
US05506190,CCCCCCN.O=C1C2=C(CCCC2)C(=O)N1c1cc(OC2CCCC2)c(Cl)cc1F>>CCCCCCNC(=O)C1=C(C(=O)Nc2cc(OC3CCCC3)c(Cl)cc2F)CCCC1,,c1ccccc1,,CCN(CC)CC,,test
US20040122029A1,COC(=O)C(Cc1cnc(Nc2ccccc2)nc1Nc1ccccc1)c1c(Cl)cccc1Cl>>O=C1C(c2c(Cl)cccc2Cl)Cc2cnc(Nc3ccccc3)nc2N1c1ccccc1,,CC(=O)O,CCOC(C)=O,O=S(=O)(O)O,,test
US20120101280A1,CC(C)(C)CN1CCC2(CC1)C[C@@H](C(=O)O)N(Cc1ccc(CN(Cc3ncc[nH]3)Cc3ncc[nH]3)cc1)C2.CN(C)C(=O)CO>>CN(C)C(=O)COC(=O)[C@@H]1CC2(CCN(CC(C)(C)C)CC2)CN1Cc1ccc(CN(Cc2ncc[nH]2)Cc2ncc[nH]2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20090108735A1,O=C(Cc1ccccc1)Cc1ccccc1.O=C1C(=O)c2ccc(Br)c3cccc1c23>>O=C1C(c2ccccc2)=C2C(=C1c1ccccc1)c1ccc(Br)c3cccc2c13,,CO,,[K+].[OH-],,test
US03985788,CCOC(=O)C(Cl)Cc1ccc(C2CCCCC2)c(Cl)c1>>O=C(O)C(Cl)Cc1ccc(C2CCCCC2)c(Cl)c1,,CC(=O)O,,Cl,,test
US05998412,O=C(OCc1ccccc1)N1CCC(c2c[nH]c3c(F)c(F)c(F)c(F)c23)CC1>>Fc1c(F)c(F)c2c(C3CCNCC3)c[nH]c2c1F,[Pd],C1CCOC1,CCO,,,test
US20040082563A1,O=c1ccccn1-c1ccc([N+](=O)[O-])cc1>>Nc1ccc(N2CCCCC2=O)cc1,,CO,,O,,test
US20100144707A1,COc1ccc(N)c(C(N)=O)c1.O=C(Cl)c1cccc([N+](=O)[O-])c1>>COc1ccc(NC(=O)c2cccc([N+](=O)[O-])c2)c(C(N)=O)c1,,ClC(Cl)Cl,,c1ccncc1,,test
US20070054935A1,Cc1ccc([Mg]Br)cc1F.N#Cc1cccc(-c2ccncc2C=O)c1>>Cc1ccc(C(O)c2cnccc2-c2cccc(C#N)c2)cc1F,,C1CCOC1,,,,test
US20020161012A1,COc1ccc(O)cc1N1CCN(C(=O)OC(C)(C)C)CC1.Cc1ccc(S(=O)(=O)OCC(F)(F)F)cc1>>COc1ccc(OCC(F)(F)F)cc1N1CCN(C(=O)OC(C)(C)C)CC1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040038995A1,Fc1nc(F)nc(F)n1.O=C(N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)OCC1c2ccccc2-c2ccccc21>>O=C(N[C@@H](Cc1c[nH]c2ccccc12)C(=O)F)OCC1c2ccccc2-c2ccccc21,,ClCCl,,c1ccncc1,,test
US20080021030A1,CC(=O)c1ccc(Br)cc1.CCOC(=O)C(=O)[O-]>>CCOC(=O)C(=O)CC(=O)c1ccc(Br)cc1,,CCO,,[Na],,test
US05519040,Brc1nccs1.CCCCO>>CCCCOc1nccs1,,CN(C)C=O,,[H][H],[H-].[Na+],test
US20160255837A1,O=[N+]([O-])O.Oc1ccc(C(F)(F)F)nc1>>O=[N+]([O-])c1cc(C(F)(F)F)ncc1O,,O=S(=O)(O)O,,,,test
US20050256198A1,CCCCCCN(Cc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2C(=O)OC)cc1>>CCCCCCN(Cc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2C(=O)O)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20160060257A1,COc1ccc(F)cc1B(O)O.Cc1ccc(S(=O)(=O)n2c(C3=CCN(C(=O)OC(C)(C)C)CC3)cc3c(Cl)c(C)cnc32)cc1>>COc1ccc(F)cc1-c1c(C)cnc2c1cc(C1=CCN(C(=O)OC(C)(C)C)CC1)n2S(=O)(=O)c1ccc(C)cc1,,C1CCOC1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20160159774A1,C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CNC4)ncc2F)C1.O=CC1CCOCC1>>C=CC(=O)N1CCC[C@@H](Nc2nc(Nc3ccc4c(c3)CN(CC3CCOCC3)C4)ncc2F)C1,,CO,,[BH3-]C#N.[Na+],,test
US20110269738A1,BrBr.CC(C)Oc1ccc(-c2nccs2)cc1C#N>>CC(C)Oc1ccc(-c2ncc(Br)s2)cc1C#N,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20100305109A1,CC(C)c1nc2ccccc2c(=O)n1N.O=C(Cl)CC12CC3CC(CC(C3)C1)C2>>CC(C)c1nc2ccccc2c(=O)n1NC(=O)CC12CC3CC(CC(C3)C1)C2,,ClC(Cl)Cl,,c1ccncc1,,test
US20060004017A1,COc1cc2ncnc(Cl)c2cc1OC.Oc1ccc2cccnc2c1>>COc1cc2ncnc(Oc3ccc4cccnc4c3)c2cc1OC,,CN(C)C=O,,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20130029938A1,CCCC[C@]1(CC)CS(=O)(=O)c2cc(CO)c(OC)cc2[C@H](c2ccccc2)N1>>CCCC[C@]1(CC)CS(=O)(=O)c2cc(C=O)c(OC)cc2[C@H](c2ccccc2)N1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20120295903A1,Cc1cc(NCC2CCCCN2Cc2ccccc2)c([N+](=O)[O-])cc1C>>Cc1cc(N)c(NCC2CCCCN2Cc2ccccc2)cc1C,[Pd],CO,,[BH4-].[Na+],,test
US04985447,COC.COc1cc(C)c(OC)c(C)c1C>>COc1c(C)c(C)c(OC)c(C=O)c1C,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20140045828A1,CC(C)(C)COc1ccc2c(c1)[C@]1(COCC(N)=N1)c1cc(Br)ccc1O2.OB(O)c1cccnc1F>>CC(C)(C)COc1ccc2c(c1)[C@]1(COCC(N)=N1)c1cc(-c3cccnc3F)ccc1O2,,C1COCCO1,,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20050181988A1,CN(C)C(On1nnc2ccccc21)=[N+](C)C.O=C(O)c1ccc(-c2nnc(-c3ccc(N4CCN(c5ncccn5)CC4)cc3)s2)cc1>>O=C(On1nnc2ccccc21)c1ccc(-c2nnc(-c3ccc(N4CCN(c5ncccn5)CC4)cc3)s2)cc1,,O,,CCN(C(C)C)C(C)C,,test
US20130096121A1,O=CCC(C1CCCCC1)n1cccn1>>OCCC(C1CCCCC1)n1cccn1,,Cc1ccccc1,,,,test
US04968689,CCOC(=O)c1c(C(C)C)nc(C(C)C)c(C(=O)OCC)c1-c1ccccc1>>CC(C)c1nc(C(C)C)c(CO)c(-c2ccccc2)c1CO,,C1CCOC1,CCOCC,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20090198063A1,CC(C)(C)OC(=O)NC1CCN(CCn2c(=O)ccc3ccncc32)CC1>>NC1CCN(CCn2c(=O)ccc3ccncc32)CC1,,CCO,,Cl,,test
US05523458,CCOC(=O)Cl.NC(=CC(=O)[C@H](Cc1ccccc1)N(Cc1ccccc1)Cc1ccccc1)Cc1ccccc1>>CCOC(=O)NC(=CC(=O)[C@H](Cc1ccccc1)N(Cc1ccccc1)Cc1ccccc1)Cc1ccccc1,,Cc1ccccc1,,O,c1ccncc1,test
US20150038437A1,CC(C)(C)N.CCCC(=O)c1ccc2c(c1)CCCN2C>>CCCC(=NC(C)(C)C)c1ccc2c(c1)CCCN2C,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20020099077A1,COC(=O)C(Cc1ccc(C(=O)C2CC2)cc1)C(=O)OC.Cl>>COC(=O)C(Cc1ccc(C(=O)CCCCl)cc1)C(=O)OC,,CCO,Cc1ccccc1,,,test
US20140005213A1,C=C(NC(=O)OC(C)(C)C)C(=O)OC.COCN(Cc1ccccc1)C[Si](C)(C)C>>COC(=O)C1(NC(=O)OC(C)(C)C)CCN(Cc2ccccc2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130172353A1,N#Cc1c(-c2ccc([N+](=O)[O-])cc2)nsc1NC(=O)Oc1ccccc1.NCCCN1CCOCC1>>N#Cc1c(-c2ccc([N+](=O)[O-])cc2)nsc1NC(=O)NCCCN1CCOCC1,,C1COCCO1,,,,test
US20120252777A1,COC(=O)c1cccc(-c2nc(Nc3cccc(N4CC5(COC5)C4)c3)c3ncsc3n2)c1>>O=C(O)c1cccc(-c2nc(Nc3cccc(N4CC5(COC5)C4)c3)c3ncsc3n2)c1,,C1CCOC1,CO,[Na+].[OH-],,test
US20130203735A1,NC(=NO)C1CCCN(Cc2ccccc2)C(=O)C1.O=C(Cl)c1ccc(F)cc1>>NC(=NOC(=O)c1ccc(F)cc1)C1CCCN(Cc2ccccc2)C(=O)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20030144282A1,COC(=O)c1ccc(NCCc2c(CCN=[N+]=[N-])n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1>>COC(=O)c1ccc(NCCc2c(CCN)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1,,C1CCOC1,CCOC(C)=O,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090099205A1,C1CCOC1.CC(=O)NCC(=O)O>>O=C(O)CN1CCCC1=O,,CO,ClCCl,Cl,[Na+].[OH-],test
US20100305096A1,Brc1cccc2nncn12.CCCC[Sn](CCCC)(CCCC)c1nc(N2CCOCC2)c2sc(CN3CCN(C(C)(C)C(N)=O)CC3)cc2n1>>CC(C)(C(N)=O)N1CCN(Cc2cc3nc(-c4cccc5nncn45)nc(N4CCOCC4)c3s2)CC1,[Cu]I,C1COCCO1,,,,test
US20130190316A1,CC(C)(C)[Si](C)(C)OCc1cccnc1-c1ccn[nH]1.COC(=O)CCBr>>COC(=O)CCn1ccc(-c2ncccc2CO[Si](C)(C)C(C)(C)C)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06734193B1,CCN1CCC(C)(C)c2cc(C(C)C)cc(Br)c21.[Li]CCCC>>CCCN1CCC(C)(C)c2cc(C(C)C)cc(Br)c21,,C1CCOC1,,CCCCCC,,test
US20140309213A1,COC(=O)c1cncc(-n2cnnn2)c1>>O=C(O)c1cncc(-n2cnnn2)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20120095215A1,Nc1nccnn1.O=C(CBr)CCO>>OCCc1cn2nccnc2n1,,CCO,,,,test
US20050256037A1,CC(C)(C)OC(=O)N[C@@H](Cc1cc(I)ccc1OCc1ccccc1)C(=O)O.OCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](Cc1cc(I)ccc1OCc1ccccc1)C(=O)OCc1ccccc1,CN(C)c1ccncc1,CC#N,,ClCCCl,,test
US20040014802A1,CCCC(=O)Cl.Nc1n[nH]c2cc(C(F)(F)F)ccc12>>CCCC(=O)Nc1n[nH]c2cc(C(F)(F)F)ccc12,,c1ccncc1,,,,test
US20140057937A1,FC(F)(F)c1cc[nH]n1.O=C1CCC(=O)N1Cl>>FC(F)(F)c1n[nH]cc1Cl,,CC#N,,,,test
US20050106304A1,CC(=O)OC[C@H]1O[C@H](O[C@]2(COC(C)=O)O[C@H](COC(=O)C(C)C)[C@@H](OC(=O)C(C)C)[C@@H]2OC(=O)C(C)C)[C@H](OC(=O)C(C)C)[C@@H](OC(=O)C(C)C)[C@@H]1OC(=O)C(C)C.O=[Si]=O>>CC(=O)OC[C@H]1O[C@H](O[C@]2(COC(C)=O)O[C@H](COC(=O)C(C)C)[C@@H](OC(=O)C(C)C)[C@@H]2OC(=O)C(C)C)[C@H](OC(=O)C(C)C)[C@@H](OC(=O)C(C)C)[C@@H]1OC(=O)C(C)C.O=[Si]=O,,CCO,,,,test
US20050245515A1,CC(C)[Si](OCc1cc2cc(C(O)(C(F)(F)F)C(F)(F)F)ccc2n1Cc1ccccc1)(C(C)C)C(C)C>>Cc1cc2cc(C(O)(C(F)(F)F)C(F)(F)F)ccc2n1Cc1ccccc1,[Pd],CO,,,,test
US20020120011A1,Nc1cccc(N(Cc2cccc(OC(F)(F)C(F)F)c2)CC(O)C(F)(F)F)c1.O=C=Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)Nc1cccc(N(Cc2cccc(OC(F)(F)C(F)F)c2)CC(O)C(F)(F)F)c1,,ClCCl,,CCN(CC)CC,,test
US05981533,CCOc1ccc(NC(SC)=C(C#N)C#N)cc1.NN>>CCOc1ccc(Nc2n[nH]c(N)c2C#N)cc1,,CO,,O,,test
US20100240669A1,N#Cc1ncc(F)cc1F.Nc1c(F)cccc1C(F)(F)F>>N#Cc1ncc(Nc2c(F)cccc2C(F)(F)F)cc1F,,CS(C)=O,,O,,test
US20020091265A1,Cc1ccccc1-c1ccncc1C(=O)O.FC(F)(F)c1cc(CNC2CC2)cc(C(F)(F)F)c1>>Cc1ccccc1-c1ccncc1C(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CC1,CN(C)C=O,ClCCl,,O=S(Cl)Cl,,test
US20030092712A1,C1COCCN1.COc1ccc(CN2Cc3c(-c4ccccc4Cl)cc(NS(=O)(=O)CCCCl)cc3N(c3c(Cl)cccc3Cl)C2=O)cc1>>COc1ccc(CN2Cc3c(-c4ccccc4Cl)cc(NS(=O)(=O)CCCN4CCOCC4)cc3N(c3c(Cl)cccc3Cl)C2=O)cc1,,CCOC(C)=O,,,,test
US20150344471A1,CCNc1ccc(C#N)c(Cl)n1.OCCOCc1ccccc1>>CCNc1ccc(C#N)c(OCCOCc2ccccc2)n1,,C1COCCO1,O,CC(C)(C)[O-].[K+],,test
US20150274663A1,C=CC(=O)OCC.CCCCCCCCOc1ccc(C2CCCNC2)cc1>>CCCCCCCCOc1ccc(C2CCCN(CCC(=O)OCC)C2)cc1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020151547A1,CC(C)(C)OC(=O)N1CCN([C@H]2CCN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)C[C@H]2c2ccccc2)CC1.CCOC1(O[Si](C)(C)C)CC1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCC(N2CCN(C3CC3)CC2)C(c2ccccc2)C1,,ClC(Cl)Cl,,,,test
US20100016285A1,BrBr.O=C(O)c1cc2ccc([N+](=O)[O-])cc2[nH]c1=O>>O=c1[nH]c2cc([N+](=O)[O-])ccc2cc1Br,,c1ccncc1,,Cl,,test
US20070173506A1,CCOC(=O)Cc1cccc(F)c1[N+](=O)[O-]>>O=C1Cc2cccc(F)c2N1,[Fe],CC(=O)O,,,,test
US20100137281A1,COC(=O)c1cc(C2CC2)sc1N.NCCc1ccccc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=c1[nH]c2sc(C3CC3)cc2c(=O)n1CCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20070232607A1,COC(=O)CO.Cc1ccc(Oc2ccc(Nc3ncnc4cccc(O)c34)cc2C)cn1>>COC(=O)COc1cccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c12,,ClCCl,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040082603A1,Fc1cccc(CBr)c1.O=C1NCc2ccc(O)cc21>>O=C1NCc2ccc(OCc3cccc(F)c3)cc21,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20060178419A1,CC(C)(C)OC(=O)N[C@H]1CCOC1=O.Nc1ccc(I)cc1F>>CC(C)(C)OC(=O)N[C@@H](CCO)C(=O)Nc1ccc(I)cc1F,,ClCCl,,C[Al](C)C,,test
US20120264731A1,COC(=O)c1cc(C2CCCN2c2ccccc2)c2oc(N3CCO[C@H](C)C3)cc(=O)c2c1>>C[C@@H]1CN(c2cc(=O)c3cc(C(=O)O)cc(C4CCCN4c4ccccc4)c3o2)CCO1,,CO,,O,[Na+].[OH-],test
US20060167016A1,Fc1ccccc1Cn1nc(-c2ncc(Br)cn2)c2cccnc21.OCc1ccccc1B(O)O>>OCc1ccccc1-c1cnc(-c2nn(Cc3ccccc3F)c3ncccc23)nc1,,COCCOC,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100137299A1,COc1ccc(CN2C(=O)C3(COc4cc5c(cc43)OCCO5)c3c2ccc2ncsc32)cc1>>O=C1Nc2ccc3ncsc3c2C12COc1cc3c(cc12)OCCO3,,ClCCl,O=C(O)C(F)(F)F,O=S(=O)(O)C(F)(F)F,,test
US20120230924A1,Cc1c[nH]c2ccccc12>>Cc1ccc2c(c1)NCC2,,CC(=O)O,,[BH3-]C#N.[Na+],,test
US06277847B1,CC(C)N1Cc2c(cccc2[N+](=O)[O-])C1=O>>CC(C)N1Cc2c(N)cccc2C1=O,[Fe],CC(=O)O,,O,,test
US20140235629A1,CC(C)(C)OC(=O)N1C(=O)OC[C@@]1(C)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)N[C@@](C)(CO)c1ccc(Cl)cc1,,CO,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20050085508A1,COC(=O)c1cc(OCCC2(CCN3CCC(N(C(=O)c4ccco4)c4ccc(C)cc4)CC3)CCCCC2)cc(C(=O)OC)c1>>Cc1ccc(N(C(=O)c2ccco2)C2CCN(CCC3(CCOc4cc(C(=O)O)cc(C(=O)O)c4)CCCCC3)CC2)cc1,,CO,,[Na+].[OH-],,test
US06136823,Cc1cc(Br)c(Cl)cc1F.O=C=O>>Cc1cc(C(=O)O)c(Cl)cc1F,,CCOCC,,O,[Li]CCCC,test
US04107431,CC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=CC1=CS[C@@H]2[C@H](NC(=O)Cc3cccs3)C(=O)N2C1C(=O)OC(c1ccccc1)c1ccccc1>>CC(=O)/C=C/C1=CS[C@@H]2[C@H](NC(=O)Cc3cccs3)C(=O)N2C1C(=O)OC(c1ccccc1)c1ccccc1,,c1ccccc1,,,,test
US03963736,CCBr.CCOC(=O)c1cnc2cc3c(cc2c1OCC)OCO3>>CCOC(=O)c1cn(CC)c2cc3c(cc2c1=O)OCO3,,Cc1ccccc1,,,,test
US04933350,CCOC(=O)/C=C/c1c(-c2ccccc2)c2c3ccccc3ccn2c1C(C)C>>CC(C)c1c(C/C=C/O)c(-c2ccccc2)c2c3ccccc3ccn12,,C1CCOC1,Cc1ccccc1,CC(C)C[Al+]CC(C)C.[H-],,test
US20090259049A1,COB(OC)OC.COc1cc(COC2CCC2)cc(OC)c1Br>>COc1cc(COC2CCC2)cc(OC)c1B(O)O,,C1CCOC1,CCOC(C)=O,[Li]CCCC,[Cl-].[NH4+],test
US20050164989A1,CCCC(=O)N[PH](=O)C1(NC(=O)OCc2ccccc2)CCCN(N)C1=O>>CCCC(=O)N[PH](=O)C1(N)CCCN(N)C1=O,[Pd],CCO,,,,test
US20080009541A1,CC(C)(C)OC(=O)N1C(=O)C(Cc2ccccc2)CC1(C)C(=O)[O-]>>COC(=O)[C@@H]1CC(Cc2ccccc2)C(=O)N1,,Cl,,C1COCCO1,,test
US04798843,CCOC(=O)CC(C)=O.COc1ccc(CC(=O)Cl)cc1>>CCOC(=O)CC(=O)Cc1ccc(OC)cc1,,CCOCC,,O,[Na],test
US20100112476A1,C=C(C(=O)OC)c1ccccc1.Nc1nc[nH]n1>>O=C1Nc2nncn2CC1c1ccccc1,,CCCCO,,,,test
US20100137317A1,CC1(C)OC(c2ccc([N+](=O)[O-])cc2)=CC1=O.O=C1CCC(=O)N1Br>>CC1(C)OC(c2ccc([N+](=O)[O-])cc2)=C(Br)C1=O,,ClC(Cl)Cl,,,,test
US20160168090A1,NCC1(O)CCC(F)(F)CC1.O=C(O)c1cn(CC(F)(F)F)c2cccc(Cl)c12>>O=C(NCC1(O)CCC(F)(F)CC1)c1cn(CC(F)(F)F)c2cccc(Cl)c12,,CC#N,CCN(CC)CC,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20130225620A1,Cc1ccc(S(=O)(=O)n2ccc3c(C=NO)cccc32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(CN)cccc32)cc1,[Zn],CCO,,[Cl-].[NH4+],,test
US20110294807A1,CCC(C)c1ccc(NC(=O)c2cc(F)ccc2N)cc1.Cc1cc(C=O)cc(C)c1OCCO>>CCC(C)c1ccc(-n2c(-c3cc(C)c(OCCO)c(C)c3)nc3ccc(F)cc3c2=O)cc1,,CCO,,,,test
US04939262,CC(=O)OC(C)=O.CCc1cc(Cl)c(N)c(Cl)n1>>CCc1cc(Cl)c(NC(C)=O)c(Cl)n1,,CC(=O)OC(C)=O,,CC(=O)[O-].[Na+],,test
US20100173909A1,CCCO[C@H]1CN(c2nc(-c3ncnn3C)c(C(=O)OC)s2)CC[C@H]1NC(=O)c1cc(Cl)c(C)[nH]1>>CCCO[C@@H]1CN(c2nc(-c3ncnn3C)c(C(=O)O)s2)CC[C@@H]1NC(=O)c1cc(Cl)c(C)[nH]1,,CO,,[Na+].[OH-],,test
US05206374,O=Cc1ccc(-c2ccccc2-c2nnn(C(c3ccccc3)(c3ccccc3)c3ccccc3)n2)cc1>>OCc1ccc(-c2ccccc2-c2nnn(C(c3ccccc3)(c3ccccc3)c3ccccc3)n2)cc1,,CC(=O)N(C)C,,O,[BH4-].[Na+],test
US20100130492A1,CC(=O)OC(C)=O.C[C@@H]1CN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC2CC2)CCN1>>CC(=O)N1CCN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC2CC2)C[C@H]1C,,CO,ClCCl,CCN(CC)CC,,test
US20070149577A1,C=CCc1cc(C(C)=O)ccc1O.COc1ccc(F)cc1B(O)O>>C=CCc1cc(C(C)=O)ccc1-c1cc(F)ccc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080312192A1,CN1CCN(C(=O)c2cc(N)cc(C(F)(F)F)c2)CC1>>CCN(CC)Cc1cc(N)cc(C(F)(F)F)c1,,C1CCOC1,,,,test
US20070049589A1,CN1CCN(c2ccc(CNC(=O)OC(C)(C)C)cc2)CC1.O=C1CCC(=O)N1Cl>>CN1CCN(c2ccc(CNC(=O)OC(C)(C)C)cc2Cl)CC1,,ClCCl,,,,test
US04824861,CC(C)COC(=O)CC(O)CN1CC(=O)N(CC(N)=O)C1C(C)C>>NC(=O)CNC(=O)CN1CC(O)CC1=O,,CN(C)C=O,O,,,test
US20050261333A1,BrCC1CO1.Oc1ccc(-c2nc3cc(Br)cnc3[nH]2)cc1>>Brc1cnc2[nH]c(-c3ccc(OCC4CO4)cc3)nc2c1,,CN(C)C=O,,[H-].[Na+],,test
US04870075,BrCc1ccccc1.COC(=O)Cc1ccccc1O>>COC(=O)Cc1ccccc1OCc1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040167129A1,CCOC(=O)c1nc(-c2ccccc2Cl)[nH]c1C>>Cc1[nH]c(-c2ccccc2Cl)nc1C(=O)O,,CCO,,[Na+].[OH-],,test
US09365522B2,CC(C)(C)OC(=O)NN.CCOC(=O)[C@H]1CCC(=O)C[C@H]1C>>CCOC(=O)[C@H]1CC[C@@H](NNC(=O)OC(C)(C)C)C[C@H]1C,,CC(=O)O,ClC(Cl)Cl,O=C([O-])O.[Na+],,test
US04771043,C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CCC2=O.O=C1CCC(=O)N1Br>>C[C@]12CC[C@H]3[C@@H](CC(Br)C4=CC(=O)C=C[C@@]43C)[C@@H]1CCC2=O,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20100204272A1,CC(C)OC1CCC(C)(C(=O)OCc2ccccc2)CC1>>CC(C)OC1CCC(C)(C(=O)O)CC1,,O,,C1CCOC1,[Li+].[OH-],test
US20040057904A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)N[C@@H]2CCCC[C@H]2N)cc1>>Cc1ccc(S(=O)(=O)N[C@@H]2CCCC[C@H]2NC(=O)OC(C)(C)C)cc1,,C1CCOC1,,[Na+].[OH-],,test
US05502044,CC(=O)NC1=C2CC[C@@H]3[C@H](CC[C@]4(C)C(=O)CC[C@@H]34)[C@@]2(C)C=CC1=O.O=C1CCC(=O)N1Br>>CC(=O)NC1=C2[C@H](Br)C[C@@H]3[C@H](CC[C@]4(C)C(=O)CC[C@@H]34)[C@@]2(C)C=CC1=O,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US05994299,Cl.ClCCN1CCCCC1.NC(N)=S>>Cl.N=C(S)NCCN1CCCCC1,,CN(C)C=O,,,,test
US20160024077A1,COC(=O)[C@@H](OC(C)(C)C)c1c(C)cn2nc(C(=O)NCC(=O)Cc3ccc(F)cc3)cc2c1N1CCC(C)(C)CC1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>Cc1cn2nc(-c3ncc(Cc4ccc(F)cc4)s3)cc2c(N2CCC(C)(C)CC2)c1[C@H](OC(C)(C)C)C(=O)O,,Cc1ccccc1,,,,test
US20150210722A1,CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)n(-c2ccc(P(C)(C)=O)cc2)n1.OC[C@@H]1CCCN1>>CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(N4CCC[C@H]4CO)n3)c3ccccc23)n(-c2ccc(P(C)(C)=O)cc2)n1,,C1COCCO1,,,,test
US20040229915A1,COC(=O)c1ccc(N2CCCC2)cc1>>O=C(O)c1ccc(N2CCCC2)cc1,,CO,O,[Na+].[OH-],,test
US04838925,Cc1cc(C)c2nccn2n1.O=C1CCC(=O)N1Br>>Cc1cc(C)c2ncc(Br)n2n1,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20140256734A1,CC(C)(C)OC(=O)NC1CCN(c2nc(C#N)cc3ccccc23)C1.CCOC(=O)NN>>NC1CCN(c2nc(-c3n[nH]c(=O)[nH]3)cc3ccccc23)C1,,CN1CCCC1=O,CO,,,test
US20150336949A1,Cc1ccc(S(=O)(=O)n2cc(-c3cnn(Cc4cccc(F)c4)c3)c3cc(-c4ccc(N5CCN(C(=O)OC(C)(C)C)CC5)cc4F)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3cnn(Cc4cccc(F)c4)c3)c3cc(-c4ccc(N5CCNCC5)cc4F)cnc32)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US04145432,C=CCOc1ccccc1C1C(C(=O)OCC)=C(C)NC(C(OCC)OCC)=C1C(=O)OCC>>C=CCOc1ccccc1C1C(C(=O)OCC)=C(C)NC(C=O)=C1C(=O)OCC,,CC(C)=O,,Cl,,test
US20100222318A1,Nc1ncc(Br)nc1C(=O)Nc1ccccc1.O=C(O)c1ccc(B(O)O)cc1>>Nc1ncc(-c2ccc(C(=O)O)cc2)nc1C(=O)Nc1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,O,N#N,O=C([O-])[O-].[Na+].[Na+],test
US20080009524A1,C1CCOC1.CI.Cc1ccc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)cc1-c1ccc(C(=O)N(C)C)cc1>>CC(C)OCc1ccc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)cc1-c1ccc(C(=O)N(C)C)cc1,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20090281131A1,CCOC(=O)CBr.COc1ccc(C2(C#N)CCc3nc(C)[nH]c(=O)c3C2)c2c1oc1ccccc12>>CCOC(=O)COc1nc(C)nc2c1CC(C#N)(c1ccc(OC)c3oc4ccccc4c13)CC2,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060211720A1,CC1(c2ccc(F)c(Br)c2)OCCO1.CN(C)C=O>>CC1(c2ccc(F)c(C=O)c2)OCCO1,,C1CCOC1,,[Li]CCCC,,test
US04623727,N#CCOc1cccc2cccnc12.NO>>NC(COc1cccc2cccnc12)=NO,,CCO,O,Cl,O=C([O-])[O-].[K+].[K+],test
US05177210,CCOC(=O)N1CC2CC3CCCN3C2C1>>C1CC2CC3CNCC3N2C1,,Cl,,O=C([O-])[O-].[K+].[K+],,test
US03974158,CCCN1CCOC(COS(=O)(=O)c2ccc(C)cc2)C1.CCOc1ccccc1N>>CCCN1CCOC(CNc2ccccc2OCC)C1.Cc1ccc(S(=O)(=O)O)cc1,,Cc1ccccc1C,,,,test
US06307054B1,CC(C)(O)c1ccc(Cl)s1.O=C(O)c1ccccc1>>C[C@H](Cc1ccc(Cl)s1)OC(=O)c1ccccc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04307235,Cl.N#CN1CCC2(CC1)CN(c1ccccc1[N+](=O)[O-])c1ccccc12>>Cl.O=[N+]([O-])c1ccccc1N1CC2(CCNCC2)c2ccccc21,,CC(=O)O,,[Na+].[OH-],,test
US20050143588A1,CC(=O)Oc1ccc(-c2coc3c(OC(C)=O)c(OC(C)=O)ccc3c2=O)cc1.COc1ccc(-c2coc3c(O)c(O)ccc3c2=O)cc1>>COc1ccc(-c2coc3c(OC(C)=O)c(OC(C)=O)ccc3c2=O)cc1,,c1ccncc1,,CC(=O)OC(C)=O,,test
US04382942,COc1cccc(C2=CCCNC2)c1.O=C(CBr)c1ccccc1>>COc1cccc(C2=CCCN(CC(=O)c3ccccc3)C2)c1,,CC(C)=O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20130116246A1,C[C@H]1CN(C(=O)OC(C)(C)C)CCN1.O=[N+]([O-])c1ccc(Br)cn1>>C[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1ccc([N+](=O)[O-])nc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040224958A1,CCNc1nc(Nc2ccccc2)ncc1C(=O)OCC>>CCNc1nc(Nc2ccccc2)ncc1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090036448A1,COc1cccc(N=C=O)c1.Cc1nc(N[C@H]2CC[C@@H](N)CC2)cc(N(C)C)n1.O=C(O)C(F)(F)F>>COc1cccc(NC(=O)N[C@@H]2CC[C@H](Nc3cc(N(C)C)nc(C)n3)CC2)c1.O=C(O)C(F)(F)F,,CS(C)=O,,,,test
US20050020830A1,CC(=O)OC(C)=O.OC1CC2C=CC1C2>>CC(=O)OC1CC2C=CC1C2,,CCN(CC)CC,,ClCCl,,test
US20100222318A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(-c2cnccc2C#N)nc1-c1nnc(-c2ccccc2)o1>>N#Cc1ccncc1-c1cnc(N)c(-c2nnc(-c3ccccc3)o2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US03992408,Cc1nc2n(c1CN1C(=O)c3ccccc3C1=O)-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2>>Cc1nc2n(c1CN)-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2,,CCO,,NN,O,test
US20130303524A1,COc1ccc(CN2CCCC(F)S2(=O)=O)c(OC)c1.O=S(=O)(c1ccccc1)N(F)S(=O)(=O)c1ccccc1>>COc1ccc(CN2CCCC(F)(F)S2(=O)=O)c(OC)c1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20150057268A1,O=C1OC(Cc2ccccc2)(c2ccccc2)C2=C1CCNC2.O=C=NCc1ccccc1>>O=C1OC(Cc2ccccc2)(c2ccccc2)C2=C1CCN(C(=O)NCc1ccccc1)C2,,ClCCl,,,,test
US20090042852A1,CCOC(=O)c1cc(C#N)c(N2CCCNCC2)nc1C.O=C=NS(=O)(=O)c1ccccc1>>CCOC(=O)c1cc(C#N)c(N2CCCN(C(=O)NS(=O)(=O)c3ccccc3)CC2)nc1C,,CC(=O)O,ClCCl,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US04927819,COc1ccc2c(c1)C=Cc1ccccc1C2CO.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc2c(c1)C=Cc1ccccc1C2COS(=O)(=O)c1ccc(C)cc1,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20120258952A1,C=Cc1cccc(Cn2nc(CC)c3c(NC(=O)c4cnc5ccccn45)cccc32)n1>>CCc1cccc(Cn2nc(CC)c3c(NC(=O)c4cnc5ccccn45)cccc32)n1,[Pd],CO,,,,test
US06685995B1,CCCc1ccc(C2CCC(C3CCC(O)CC3)CC2)cc1.O=C(c1cccc2[nH]nnc12)C(F)(F)F>>CCCc1ccc(C2CCC(C3CCC(OC(=O)C(F)(F)F)CC3)CC2)cc1,,C1CCOC1,,,,test
US20070244132A1,CC1(C)OCC(COCCO[Si](C)(C)C(C)(C)C)O1.CS(=O)(=O)Cl>>CC1(C)OCC(COCCOS(C)(=O)=O)O1,,C1CCOC1,CCN(CC)CC,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US04260633,CC(C)[C@@H](Nc1ccc(C(F)(F)F)cc1)C(=O)O.O=C1CCC(=O)N1Cl>>CC(C)[C@@H](Nc1ccc(C(F)(F)F)cc1Cl)C(=O)O,,ClC(Cl)(Cl)Cl,,,,test
US20090111859A1,CCOC(=O)C[C@@H](CC)c1ccc(OCc2ccc(C(C)(C)C)c(-c3cc(OC)ccc3F)c2)cc1>>CC[C@H](CC(=O)O)c1ccc(OCc2ccc(C(C)(C)C)c(-c3cc(OC)ccc3F)c2)cc1,,C1CCOC1,CO,[Li+].[OH-],,test
US20130059834A1,CC(C)(C)N.C[Si](C)(C)CCOCn1cc(C(=O)O)c2nc(Br)cnc21>>CC(C)(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Br)nc12,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20010025111A1,CI.CS(=O)(=O)CC#N.S=C=Nc1ccc2c(c1)OCO2>>CSC(Nc1ccc2c(c1)OCO2)=C(C#N)S(C)(=O)=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030004158A1,CC(C)Oc1ccc(NC(=O)N2CCNCC2)cc1.CCOC(=O)c1cnc2cc(OCCCC3CCCNC3)c(OC)cc2c1Cl>>CCOC(=O)c1cnc2cc(OCCCN3CCCCC3)c(OC)cc2c1N1CCN(C(=O)Nc2ccc(OC(C)C)cc2)CC1,,CN(C)C=O,,Cl,,test
US20070093521A1,CCOc1cc(CN2CCC(Nc3nc4cccc(N)c4o3)CC2)cc(OCC)c1F.Cn1cnc(S(=O)(=O)Cl)c1>>CCOc1cc(CN2CCC(Nc3nc4cccc(NS(=O)(=O)c5cn(C)cn5)c4o3)CC2)cc(OCC)c1F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070149506A1,C1=COCCC1.Cc1[nH]nc(C(F)(F)F)c1Br>>Cc1c(Br)c(C(F)(F)F)nn1C1CCCCO1,,ClC(Cl)Cl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20080153810A1,CN(C1(C(=O)OC(C)(C)C)NNc2ccc([N+](=O)[O-])cc21)S(C)(=O)=O>>CN(C1(C(=O)OC(C)(C)C)NNc2ccc(N)cc21)S(C)(=O)=O,[Pd],CO,,,,test
US20050085508A1,CC(C)(C)[Si](OCCC1(CCO)CCCCC1)(c1ccccc1)c1ccccc1.COC(=O)c1cc(O)cc(C(=O)OC)c1>>COC(=O)c1cc(OCCC2(CCO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)CCCCC2)cc(C(=O)OC)c1,,c1ccccc1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070082890A1,CCOC(=O)Cn1cccc(Br)c1=O.NN>>NNC(=O)Cn1cccc(Br)c1=O,,CCCCO,,O,,test
US20090062292A1,CC[C@@H]1c2nncn2-c2cnc(Cl)nc2N1C1CCCC1.NC1CC1>>CC[C@@H]1c2nncn2-c2cnc(NC3CC3)nc2N1C1CCCC1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20110319429A1,CC(C)(C)OC(=O)N(Cc1ccccn1)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N(Cc1ccccn1)c1ccc(N)cc1,[Pd],CO,,,,test
US20140213591A1,N#Cc1ccccc1F.Oc1ccccc1>>N#Cc1ccccc1Oc1ccccc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20090196912A1,COc1cc(CNc2cncc(-c3cccc(O)c3)c2)ccc1C>>Cc1ccc(CNc2cncc(-c3cccc(O)c3)c2)cc1O,,ClCCl,,,,test
US20130184459A1,COc1cccc(-c2nc(=O)[nH]c3c2ccc2ccccc23)c1>>O=c1nc(-c2cccc(O)c2)c2ccc3ccccc3c2[nH]1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20100160303A1,CS(=O)(=O)Cl.NC(=O)c1ccc(-c2ccccc2F)c2c1[nH]c1cc(CO)ccc12>>CS(=O)(=O)OCc1ccc2c(c1)[nH]c1c(C(N)=O)ccc(-c3ccccc3F)c12,,C1CCOC1,CCOC(C)=O,,,test
US20110172230A1,Nc1ccc(Cl)nn1.OCc1ccccc1>>Nc1ccc(OCc2ccccc2)nn1,,O,,[H-].[Na+],,test
US20090048258A1,CC(C)(C)O.O=C(O)c1cc(-c2ccccc2)cc(-c2ccccc2)c1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)Nc1cc(-c2ccccc2)cc(-c2ccccc2)c1,,Cc1ccccc1,,CCN(CC)CC,,test
US06548474B1,C=CCCl.O=C1CCCC1=C1CCCC1>>C=CCC1(C2=CCCC2)CCCC1=O,,C1CCOC1,,O,[H-].[Na+],test
US06833387B1,CCOC(=O)c1c(OCC2COC(C)(C)O2)c2ccccc2n1Cc1ccc(Cl)c(Cl)c1>>CCOC(=O)c1c(OCC(O)CO)c2ccccc2n1Cc1ccc(Cl)c(Cl)c1,,C1CCOC1,Cl,,,test
US20090253699A1,COC(=O)c1cccc(C(=O)CC(=O)c2ccc(C(C)C)cc2)c1>>CC(C)c1ccc(C(=O)CC(=O)c2cccc(C(=O)O)c2)cc1,,CO,O,Cl,[Li]O,test
US20070299068A1,COc1ccc2cc(-c3ccc(NC(=O)OC(C)C)cc3)[nH]c2c1.O=C1CCC(=O)N1Cl>>COc1ccc2c(Cl)c(-c3ccc(NC(=O)OC(C)C)cc3)[nH]c2c1,,CN(C)C=O,O,,,test
US20050009828A1,COC(=O)c1cnc2[nH]c(C(=O)NC3CCN(C(C)C)CC3)cc2c1.Clc1ccc(-c2cc(CBr)no2)s1>>COC(=O)c1cnc2c(c1)cc(C(=O)NC1CCN(C(C)C)CC1)n2Cc1cc(-c2ccc(Cl)s2)on1,,CN(C)C=O,,O,[H-].[Na+],test
US20080242672A1,CS(=O)(=O)OCCn1ccc2c1nc(N)n1nc(-c3ccco3)nc21.O=C(Cc1ccc(F)cc1F)N1CCNCC1>>Nc1nc2c(ccn2CCN2CCN(C(=O)Cc3ccc(F)cc3F)CC2)c2nc(-c3ccco3)nn12,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20060106022A1,COc1ccc(-c2cnc3[nH]c(=O)n(Cc4ccccc4)c3n2)cc1C(=O)O>>O=C(O)c1cc(-c2cnc3[nH]c(=O)n(Cc4ccccc4)c3n2)ccc1O,,ClCCl,,BrB(Br)Br,,test
US05206233,COc1ccc(C2CCNCCS2)cc1.ClCCCCc1ccncc1>>COc1ccc(C2CCN(CCCCc3ccncc3)CCS2)cc1,,CC#N,,O=C([O-])O.[K+],,test
US20120322841A1,CC1(C)CC(c2ccc(Cl)cc2)CC1=O.CN(C)C(OC(C)(C)C)N(C)C.NN>>CC1(C)CC(c2ccc(Cl)cc2)c2cn[nH]c21,,CC(C)O,,O,,test
US05071863,Cc1cc(C)c(O)c(N)c1.NC(N)=O>>Cc1cc(C)c2oc(=O)[nH]c2c1,,CCO,,,,test
US20080261969A1,CC(C)(C)[Si](C)(C)Oc1ccc([N+](=O)[O-])c(N)c1>>CC(C)(C)[Si](C)(C)Oc1ccc(N)c(N)c1,[Pd],CO,,,,test
US04826869,CCCCn1cccc1CC.O=C(Cl)c1cccc([N+](=O)[O-])c1>>CCCCn1c(CC)ccc1C(=O)c1cccc([N+](=O)[O-])c1,,Cc1ccccc1,,,,test
US06294531B1,COc1ccc(CC(=O)O)c(O)c1.O=[N+]([O-])c1ccccc1F>>COc1ccc(CC(=O)O)c(Oc2cccc([N+](=O)[O-])c2)c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04595780,CN(C)S(=O)(=O)Cl.COC(=O)c1ccc(N)cc1>>COC(=O)c1ccc(NS(=O)(=O)N(C)C)cc1,,c1ccncc1,,Cl,,test
US05002963,CCBr.O=C(O)C(=O)Cc1c[nH]c2ccccc12>>CCOC(=O)C(=O)Cc1c[nH]c2ccccc12,,c1ccccc1,,C1CCC2=NCCCN2CC1,,test
US20080269131A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)/C=C/CBr.NCCS>>CCOC(=O)CC1CSCCN1C(=O)OC(C)(C)C,,ClC(Cl)Cl,,CCN(CC)CC,,test
US05547962,Cc1c(N2C[C@@H](NC(=O)C(F)(F)F)C(C)(C)C2)c(F)c(N)c2c(=O)c(C(=O)O)cn(C3CC3)c12>>Cc1c(N2C[C@@H](N)C(C)(C)C2)c(F)c(N)c2c(=O)c(C(=O)O)cn(C3CC3)c12,,O,,Cl,[K+].[OH-],test
US05658935,CCOC(=O)CC(Cc1ccncc1)(C(=O)OCC)C(=O)OCC>>CCOC(=O)C(CC(=O)O)(Cc1ccncc1)C(=O)OCC,,Cl,,,,test
US20090137561A1,COC(=O)CCc1cccc(O)c1.Cc1cc(CCl)ccc1Br>>COC(=O)CCc1cccc(OCc2ccc(Br)c(C)c2)c1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020161005A1,Br.COc1cccc(C(O)(c2cccnc2)C2CC2)c1>>COc1cccc(C(=CCCBr)c2cccnc2)c1,,CC(=O)O,CCOC(C)=O,O,[Na+].[OH-],test
US20130072490A1,CCOC(=O)CC1(c2ccc(-c3ccc(-c4onc(C)c4NC(C)c4cc(-c5ccccc5)no4)cc3)cc2)CC1>>Cc1noc(-c2ccc(-c3ccc(C4(CC(=O)O)CC4)cc3)cc2)c1NC(C)c1cc(-c2ccccc2)no1,,C1CCOC1,,CCO,[Na+].[OH-],test
US20150329523A1,Cc1ccc(-n2nc(C(C)(C)C(F)(F)F)cc2N)cc1.O=C(Cl)Oc1ccccc1>>Cc1ccc(-n2nc(C(C)(C)C(F)(F)F)cc2NC(=O)Oc2ccccc2)cc1,,C1CCOC1,ClCCl,O=C([O-])O.[Na+],,test
US20140235671A1,CCOC(=O)CCCCCCN(c1ccccn1)c1cc(-c2ccccc2C)ccn1.NO>>Cc1ccccc1-c1ccnc(N(CCCCCCC(=O)NO)c2ccccn2)c1,,CN(C)C=O,CO,,,test
US20090099189A1,CCCCB(O)O.CCOC(=O)COc1ccc(Br)cc1C(=O)c1cnn(-c2ccccc2)c1>>CCCCc1ccc(OCC(=O)O)c(C(=O)c2cnn(-c3ccccc3)c2)c1,,C1CCOC1,O,,,test
US20030207878A1,Cc1cc2c(F)c(O)ccc2[nH]1.Clc1nnc(Cc2ccncc2)c2ccccc12>>Cc1cc2c(F)c(Oc3nnc(Cc4ccncc4)c4ccccc34)ccc2[nH]1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030096835A1,CN(C(=O)CCCCOCCn1cnc2c[n+]([O-])c3ccccc3c21)c1ccccc1.O=C=NC(=O)C(Cl)(Cl)Cl>>CN(C(=O)CCCCOCCn1cnc2c(N)nc3ccccc3c21)c1ccccc1,,ClCCl,,,,test
US20140213586A1,COc1cncc(NC(C(=O)c2c[nH]c3c(CCOC(C)=O)cccc23)c2ccc(F)cc2)c1>>COc1cncc(NC(C(=O)c2c[nH]c3c(CCO)cccc23)c2ccc(F)cc2)c1,,C1CCOC1,CO,O=C([O-])[O-].[K+].[K+],,test
US20080255124A1,CC(C)(C)CN(CC=O)c1ccc(C#N)c(C(F)(F)F)c1>>CC(C)(C)CN(CCO)c1ccc(C#N)c(C(F)(F)F)c1,,CO,,[BH4-].[Na+],[Cl-].[NH4+],test
US20120022066A1,Clc1cc(-c2ccccc2)nc(Cl)n1.NN>>NNc1cc(-c2ccccc2)nc(Cl)n1,,C1COCCO1,,O,,test
US20160002218A1,Nc1nc(-c2csc(Cl)c2)cs1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1nc(-c2csc(Cl)c2)cs1)C(F)(F)F,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,ClCCl,test
US20130018055A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=C(NC1(C(=O)NC2CCc3cc(Br)ccc32)CC1)C(F)(F)F>>CC1(C)OB(c2ccc3c(c2)CCC3NC(=O)C2(NC(=O)C(F)(F)F)CC2)OC1(C)C,Cl[Pd]Cl,C1COCCO1,,O,CC(=O)[O-].[K+],test
US20100160308A1,COC(Cc1ccc([N+](=O)[O-])c(Nc2nc(-c3cccc(Cl)c3)c(C(N)=O)s2)c1)OC>>NC(=O)c1sc(Nc2cc(CC=O)ccc2[N+](=O)[O-])nc1-c1cccc(Cl)c1,,O,,O=CO,,test
US20070167447A1,C#Cc1ccccc1.COC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(NC(=O)C(F)(F)F)c1>>COC(=O)c1ccc2cc(-c3ccccc3)[nH]c2c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOCC,CN(C)C=O,CN(C)C(=N)N(C)C,,test
US04367238,C=CCOc1ccccc1Oc1ccccc1C.CC(=O)OC(C)=O>>C=CCc1cccc(Oc2ccccc2C)c1OC(C)=O,,O,,c1ccncc1,,test
US20120178734A1,C=CCOC(=O)C1(NC(=O)c2cnc3n2[C@](C)(Cc2ccc(C#N)cc2)C(=O)N3c2cc(Cl)c(F)c(Cl)c2)CC1>>C[C@@]1(Cc2ccc(C#N)cc2)C(=O)N(c2cc(Cl)c(F)c(Cl)c2)c2ncc(C(=O)NC3(C(=O)O)CC3)n21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,C1COCCN1,,test
US05510353,CCCCCCCN(C)C(N)=NN=Cc1c[nH]c2ccc(OCc3ccccc3)cc12>>CCCCCCCN(C)C(N)=NN=Cc1c[nH]c2ccc(O)cc12,[Pd],CCO,,,,test
US20090311217A1,CNCCN(C)C.COc1ccc2c(c1)c(C=O)c(-c1c(C)nn(C)c1C)n2CCCl>>COc1ccc2c(c1)c(C=O)c(-c1c(C)nn(C)c1C)n2CCN(C)CCN(C)C,,O,,Cl,,test
US20110118245A1,C1COCCN1.CC(C)(COS(=O)(=O)c1ccc([N+](=O)[O-])cc1)c1cc(N)no1>>CC(C)(CN1CCOCC1)c1cc(N)no1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20020099216A1,C=Cc1cccc(C2(C)CCN(CCCCCC)CC2C)c1.O=[Os](=O)(=O)=O>>CCCCCCN1CCC(C)(c2cccc(C=O)c2)C(C)C1,O=[Os](=O)(=O)=O,CC(C)=O,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20100120880A1,CO.C[O-].Cc1csc2n1c1ccccc1[n+]2Cc1ccc([N+](=O)[O-])cc1>>CS/C=C(/C)n1c(=O)n(Cc2ccc([N+](=O)[O-])cc2)c2ccccc21,,CO,,[Cl-].[Na+],,test
US20030207939A1,CC(C)c1cccc(C(C)C)c1N=C=O.CN(C)c1ccc(CNc2ccc(F)cc2)cc1>>CC(C)c1cccc(C(C)C)c1NC(=O)N(Cc1ccc(N(C)C)cc1)c1ccc(F)cc1,,c1ccccc1,,,,test
US20140378475A1,COc1cccc(C(=O)Nc2cccc(Br)c2C)c1N.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cccc2c(=O)n(-c3cccc(Br)c3C)c(=O)[nH]c12,,C1CCOC1,,O=C([O-])O.[Na+],,test
US05153207,CCOC(=O)Cl.CN1CCC(OC(c2ccccc2)c2ccc(F)cc2)CC1>>CCOC(=O)N1CCC(OC(c2ccccc2)c2ccc(F)cc2)CC1,,Cc1ccccc1,,,,test
US20100121048A1,Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2CC(=O)O)c(-c2ccccc2)n1-c1ccccc1.c1ccc(-c2nnn[nH]2)cc1>>Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2Cc2nnc(-c3ccccc3)o2)c(-c2ccccc2)n1-c1ccccc1,,Cc1ccccc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20150274696A1,Fc1cn2nccc2nc1Cl.N>>Nc1nc2ccnn2cc1F,,CO,,,,test
US20110015181A1,CC(C)(C)OC(=O)N1CCCC(C=O)C1.Cc1nc(SCc2cc(N3CCOCC3)cc(N)n2)oc1C>>Cc1nc(SCc2cc(N3CCOCC3)cc(NCC3CCCN(C(=O)OC(C)(C)C)C3)n2)oc1C,,C1CCOC1,CC(=O)O,O=C([O-])O.[Na+],,test
US20140051672A1,CNC1CC(C)(C)NC(C)(C)C1.Clc1ccc(Cl)nn1>>CN(c1ccc(Cl)nn1)C1CC(C)(C)NC(C)(C)C1,,CCCCO,,,,test
US20080194520A1,C#C/C=C/S(=O)(=O)N1CCN(c2ccccn2)CC1.NO>>C#CC(CS(=O)(=O)N1CCN(c2ccccn2)CC1)NO,,C1CCOC1,,,,test
US20100105744A1,CCOC(=O)C(C)C(c1ccc(Cl)cc1F)c1cn(C(=O)OC(C)(C)C)c2c(CSC)cccc12>>CSCc1cccc2c(C(c3ccc(Cl)cc3F)C(C)CO)c[nH]c12,,C1CCOC1,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20100160285A1,COC(=O)COc1ccc(C(F)(F)F)cc1-c1ccc(S(=O)(=O)C(C)C)c(F)c1>>CC(C)S(=O)(=O)c1ccc(-c2cc(C(F)(F)F)ccc2OCC(=O)O)cc1F,,[Na+],[OH-],CO,,test
US20150087631A1,CC(C)CNCC(O)c1ccccc1.Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1>>CC(C)CNCC(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20040102492A1,COc1c(N)cc(C2(C)CC2)cc1N.CS(=O)(=O)Cl>>COc1c(N)cc(C2(C)CC2)cc1NS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20140249244A1,COCCOc1ccc(C(=O)O)cc1.O=C(/C=C/c1ccc(O)cc1)OCCCCCCCl>>COCCOc1ccc(C(=O)Oc2ccc(/C=C/C(=O)OCCCCCCCl)cc2)cc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20110263598A1,COc1ccc2c(c1)/C(=C\c1ccc3c(-c4ccc(N5CCOCC5)nc4)nn(COCC[Si](C)(C)C)c3c1)C(=O)N2.C[S+](C)(C)=O>>COc1ccc2c(c1)[C@]1(C[C@H]1c1ccc3c(-c4ccc(N5CCOCC5)nc4)nn(COCC[Si](C)(C)C)c3c1)C(=O)N2,,CN(C)C=O,,[H-].[Na+],,test
US20120142668A1,CC[C@@H](/C=C/C(=O)O)NC(=O)[C@@H]1CCCCN1C(=O)OC(C)(C)C.c1ccc2c(c1)CCN2>>CC[C@@H](/C=C/C(=O)N1CCc2ccccc21)NC(=O)[C@@H]1CCCCN1C(=O)OC(C)(C)C,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040242494A1,CC[C@@H](C(=O)OC(C)(C)C)n1cccc(NC(C)=O)c1=O>>CC[C@@H](C(=O)O)n1cccc(NC(C)=O)c1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020193367A1,CN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3ccnn3)c2)cc1Cl>>CN(C)c1cc2c(cc1Cl)NC(=O)CC(c1cccc(-n3ccnn3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040014962A1,CC(C)N(CCNC(=O)OCc1ccc([N+](=O)[O-])cc1)C(=O)c1csc(N2CC(O)C2)n1.CS(=O)(=O)Cl>>CC(C)N(CCNC(=O)OCc1ccc([N+](=O)[O-])cc1)C(=O)c1csc(N2CC(OS(C)(=O)=O)C2)n1,,ClCCl,,CCN(CC)CC,,test
US20020040043A1,N#Cc1ccc(CCO)cc1.Oc1cc(O)cc(Cl)c1>>N#Cc1ccc(CCOc2cc(O)cc(Cl)c2)cc1,,CCOCC,ClCCl,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080176830A1,CCOC(=O)/C=C/c1cc(-c2ccc(C(F)(F)F)c(F)c2)cc(F)c1N>>O=C1CCc2cc(-c3ccc(C(F)(F)F)c(F)c3)cc(F)c2N1,[Pd],CCO,,[H][H],,test
US20070032515A1,COC(=O)c1cc([N+](=O)[O-])cc2c1OCCO2>>COC(=O)c1cc(N)cc2c1OCCO2,[Pd],CCOC(C)=O,,,,test
US20010039285A1,COc1cccc(CCN)c1.O=C(Cl)C1CCN(C(=O)C(F)(F)F)CC1>>COc1cccc(CCNC(=O)C2CCN(C(=O)C(F)(F)F)CC2)c1,,ClCCl,,CCN(CC)CC,,test
US20150218151A1,O=C(NO)Oc1ccccc1.O=C(Nc1ncc(F)s1)[C@H](C[C@H]1CCNC1)c1ccc(S(=O)(=O)C2CC2)cc1>>O=C(Nc1ncc(F)s1)[C@H](C[C@H]1CCN(C(=O)NO)C1)c1ccc(S(=O)(=O)C2CC2)cc1,,CCO,,O,,test
US20080085890A1,CN1CCN(c2ncc(N)cn2)CC1.COC=C1C(=O)NC(=O)c2ccc(I)cc21>>CN1CCN(c2ncc(N/C=C3\C(=O)NC(=O)c4ccc(I)cc43)cn2)CC1,,CN(C)C=O,,,,test
US20130210844A1,CCO.O=[N+]([O-])c1cccc2c(Cl)ncnc12>>CCOc1ncnc2c([N+](=O)[O-])cccc12,,C1CCOC1,,[H-].[Na+],,test
US20150005277A1,NC(=O)c1c(N)c2cc([N+](=O)[O-])ccc2n1-c1ccc(Oc2ccccc2)cc1>>NC(=O)c1c(N)c2cc(N)ccc2n1-c1ccc(Oc2ccccc2)cc1,[Pd],CO,,,,test
US04251658,CCOC(=O)c1cnn(-c2ccc(N(CCO)CCO)nn2)c1N.NN>>NNC(=O)c1cnn(-c2ccc(N(CCO)CCO)nn2)c1N,,C1COCCO1,,O,,test
US05563144,CC1(C)CNC(=O)c2ccccc21.ClCCCBr>>CC1(C)CN(CCCCl)C(=O)c2ccccc21,,C1CCOC1,,O,[Li]CCCC,test
US20050059650A1,CC(C)(C)OC(=O)N1CCC(O)CC1.CS(=O)(=O)c1ccc(-n2ncc3c(Cl)ncnc32)c(F)c1>>CC(C)(C)OC(=O)N1CCC(Oc2ncnc3c2cnn3-c2ccc(S(C)(=O)=O)cc2F)CC1,,ClCCl,,C1CCOC1,[H-].[Na+],test
US20050171347A1,CCOC(=O)N1CCC(N)CC1.O=S(=O)(Cl)c1ccc2ccccc2c1>>CCOC(=O)N1CCC(NS(=O)(=O)c2ccc3ccccc3c2)CC1,,ClCCl,,,,test
US20050065032A1,CC(C)NC(C)C.CCC#CC(C)(C)NC(=O)C(CC)Oc1cncc(C(=O)O)c1>>CCC#CC(C)(C)NC(=O)C(CC)Oc1cncc(C(=O)N(C(C)C)C(C)C)c1,,CN(C)C=O,O,,,test
US20060014816A1,COc1ccc(C(c2ccc(OC)cc2)n2nc(-c3ccsc3)c3c2-c2ccc(CN)cc2C3)cc1.NCCN1CCOCC1.O=C(n1ccnc1)n1ccnc1>>COc1ccc(C(c2ccc(OC)cc2)n2nc(-c3ccsc3)c3c2-c2ccc(CNC(=O)NCCN4CCOCC4)cc2C3)cc1,,C1CCOC1,,,,test
US04935516,CC#N.CCN(CC)CC.Cc1ccccn1.O>>CCc1cc(O)ncn1,,CC(=O)O,,,,test
US20100105744A1,Br[Mg]C1CC1.C1CCOC1.O=C1CCc2cc(Cl)ccc21.O=C1CCc2ccc(Cl)cc21>>OC1(C2CC2)CCc2cc(Cl)ccc21.OC1(C2CC2)CCc2ccc(Cl)cc21,,C1CCOC1,CCOCC,,,test
US04680402,O=C(c1ccc(Cl)cc1)c1cc([N+](=O)[O-])ccc1Cl.OC1CCNCC1>>O=C(c1ccc(Cl)cc1)c1cc([N+](=O)[O-])ccc1N1CCC(O)CC1,,CCO,,O=C([O-])[O-].[Ca+2],,test
US20060074118A1,NC(=O)c1ccc(F)cc1.O=C(Cl)C(=O)Cl>>O=C=NC(=O)c1ccc(F)cc1,,ClCCl,,,,test
US05834454,CCOC(=O)c1cc2c(Cl)c(O)cc3c2n1CCCCC3=O.COCCl>>CCOC(=O)c1cc2c(Cl)c(OCOC)cc3c2n1CCCCC3=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130267510A1,CC1CCOc2cccc(O)c21.O=[N+]([O-])c1ccc(Cl)nc1>>CC1CCOc2cccc(Oc3ccc([N+](=O)[O-])cn3)c21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06583154B1,CC(Cl)OC(=O)Cl.CN1[C@H]2CCC[C@@H]1CC2>>C1CC2CCC(C1)N2.Cl,,Cc1ccccc1,,,,test
US20150267159A1,CC(C)(Br)C(=O)O.CCCCS.S=C=S>>CCCCSC(=S)SC(C)(C)C(=O)O,,CC(C)=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140206663A1,CC1C(=O)NN=C2COc3cc(Br)c(C4CCN(C(=O)OC(C)(C)C)CC4)cc3N21.OB(O)c1ccccc1>>CC1C(=O)NN=C2COc3cc(-c4ccccc4)c(C4CCN(C(=O)OC(C)(C)C)CC4)cc3N21,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US06130217,BrCCOc1ccccc1-c1nc2ccccc2s1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>c1ccc(C(c2ccccc2)N2CCN(CCOc3ccccc3-c3nc4ccccc4s3)CC2)cc1,,CC(C)(C)O,,,,test
US04244963,C=O.O=C(O)CS(=O)(=O)c1ccccc1.OC1CCNCC1>>C=C(CN1CCC(O)CC1)S(=O)(=O)c1ccccc1,,C1COCCO1,O,O=C=O,,test
US20050282857A1,CCOC(=O)[C@H](O)Cc1cc(Cl)c(N)c(C(F)(F)F)c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.O=C1Nc2ccccc2CCN1C1CCNCC1>>CCOC(=O)[C@@H](Cc1cc(Cl)c(N)c(C(F)(F)F)c1)OC(=O)N1CCC(N2CCc3ccccc3NC2=O)CC1,CN(C)c1ccncc1,c1ccncc1,,,,test
US05374638,CCCc1cc(Cn2c(CC)nc3c(C)cc(C(=O)O)nc32)ccc1OC(C(=O)OC(C)(C)C)c1ccccc1>>CCCc1cc(Cn2c(CC)nc3c(C)cc(C(=O)O)nc32)ccc1OC(C(=O)O)c1ccccc1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20130190332A1,CC(C)(C)OC(=O)NC1(c2ccc(C(=O)C(Br)c3ccccc3)cc2)CCC1.COc1ccc(COc2ccnc(N)n2)cn1>>COc1ccc(COc2ccn3c(-c4ccccc4)c(-c4ccc(C5(NC(=O)OC(C)(C)C)CCC5)cc4)nc3n2)cn1,,CCO,,,,test
US20100261710A1,CC(C)(C)OC(=O)N(CCO)Cc1cccc2cc[nH]c12.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N(CCOS(C)(=O)=O)Cc1cccc2cc[nH]c12,,ClCCl,,CCN(CC)CC,,test
US20020028823A1,CC(=O)O[C@@H](C)CCCCn1c(=O)c2c(ncn2Cc2ccccc2)n(C)c1=O>>C[C@H](O)CCCCn1c(=O)c2c(ncn2Cc2ccccc2)n(C)c1=O,,CCOCC,CO,Cl,,test
US20150232459A1,COC(=O)NCCCn1nc(C(C)=O)c2ccc(C)nc21.NC1CC1>>COC(=O)NCCCn1nc(C(C)=NC2CC2)c2ccc(C)nc21,,CCO,,CC(=O)O,,test
US20110263582A1,C=CC[C@]1(c2ccc(F)cc2)CCN([C@@H](C)C(C)(C)C)C(=O)O1.O=[O+][O-]>>O=C1NCCC(CCO)(c2ccc(F)cc2)O1,,ClCCl,,[BH4-].[Na+],,test
US04806541,O=C(O)c1cn(C2CC2)c2c(F)c(N3CCC[C@H]3CO)c(F)cc2c1=O>>O=C(O)c1cn(C2CC2)c2c3c(c(F)cc2c1=O)N1CCC[C@H]1CO3,,CN(C)C=O,,[H][H],[H-].[Na+],test
US08901087B2,CN(C)C1=N[C@H]2[C@H](O[C@H](COC(=O)c3ccccc3)[C@H]3OC(C)(C)O[C@H]23)S1>>CN(C)C1=N[C@H]2[C@H](O[C@H](CO)[C@H]3OC(C)(C)O[C@H]23)S1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20090233920A1,CC(C)C(=O)Cl.COCCCOc1cc(CN(C(=O)[C@H]2C[C@@H](N)CN(C(=O)OCC3c4ccccc4-c4ccccc43)C2)C2CC2)ccc1Cl>>COCCCOc1cc(CN(C(=O)[C@@H]2CNC[C@H](NC(=O)C(C)C)C2)C2CC2)ccc1Cl,,CC#N,,Cl,,test
US20100087634A1,COC(=O)C(CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)CNC(=O)c1ccc(N=Nc2ccc(N(C)C)cc2)cc1>>O=C(O)CCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F,,CO,O,[Na+].[OH-],,test
US05840917,CC(=O)c1ccsc1.OCCO>>CC1(c2ccsc2)OCCO1,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,,,test
US20030191122A1,Cc1nc2c(c(C)c(C)n2-c2c(Br)cc(C(F)(F)F)cc2Br)c(=O)[nH]1.O=P(Cl)(Cl)Cl>>Cc1nc(Cl)c2c(C)c(C)n(-c3c(Br)cc(C(F)(F)F)cc3Br)c2n1,,O,,,,test
US04464381,Clc1ccc(C2(CBr)OC2c2ccc(Cl)cc2Cl)cc1.c1c[nH]cn1>>Clc1ccc(C2(Cn3ccnc3)OC2c2ccc(Cl)cc2Cl)cc1,,CN(C)C=O,,C[O-].[Na+],,test
US20120252779A1,Clc1ncc2cn[nH]c2n1.Cn1cc(N)cn1>>Cn1cc(Nc2ncc3cn[nH]c3n2)cn1,,CC(C)O,,Cl,,test
US04153703,CC(=O)C(Br)c1ccccc1.NC(=S)c1ccccc1Cl>>Cc1nc(-c2ccccc2Cl)sc1-c1ccccc1,,CCO,,,,test
US20160120841A1,COC(=O)c1cccc(C2CC(O)c3ccncc3O2)c1>>COC(=O)c1cccc(C2CC(=O)c3ccncc3O2)c1,,CC(C)=O,,O=S(=O)(O)O,O=[Cr](=O)=O,test
US20120157609A1,C=C(C)C(=O)Cl.CC(C)C(=O)C(C)(C)C(=O)OCC(C)(C)CO>>C=C(C)C(=O)OCC(C)(C)COC(=O)C(C)(C)C(=O)C(C)C,CN(C)c1ccncc1,O,,CCN(CC)CC,ClCCl,test
US20090247534A1,Clc1ncc(Br)cn1.Nc1cccc(F)c1>>Fc1cccc(Nc2ncc(Br)cn2)c1,,O,,CCO,Cl,test
US20120157432A1,CC(C)(C)OC(=O)N1CCC(c2nnn[nH]2)CC1>>C1CC(c2nnn[nH]2)CCN1,,C1COCCO1,Cl,,,test
US20110046334A1,O=C(O)C(Cl)CO.OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>O=C(OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(Cl)CO,,CCOCC,,Cl,,test
US20140121206A1,COC(=O)C1CCCC(=O)C1.C[S+](C)(C)=O>>COC(=O)C1CCCC2(CO2)C1,,CS(C)=O,O,[H-].[Na+],,test
US20040023938A1,Cc1ccc(S(=O)(=O)Nc2ccccc2C#N)cc1.O=[N+]([O-])O>>Cc1ccc(S(=O)(=O)Nc2ccc([N+](=O)[O-])cc2C#N)cc1,,CC(=O)OC(C)=O,,,,test
US20140371278A1,CC1(C)OCC(CONC(=O)c2cc3scnc3c(F)c2Nc2ccc(I)cc2F)O1>>O=C(NOCC(O)CO)c1cc2scnc2c(F)c1Nc1ccc(I)cc1F,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20080045554A1,CCCCCn1c2nc[nH]c2c(=O)n2c(CCc3nnc(-c4ccccc4)o3)nnc12.O=C1CCC(=O)N1Br>>CCCCCn1c2nc(Br)[nH]c2c(=O)n2c(CCc3nnc(-c4ccccc4)o3)nnc12,,C1CCOC1,,,,test
US20110039812A1,C[C@@H](NC(=O)OC(C)(C)C)C(=O)O.OCCCO>>C[C@@H](NC(=O)OC(C)(C)C)C(=O)OCCCO,CN(C)c1ccncc1,CN(C)C=O,,Cl,,test
US20150239845A1,COc1cc(C(O)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc2c(Br)ccnc12>>COc1cc(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc2c(Br)ccnc12,,ClCCl,ClCCl,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US03950353,CN=C=S.NCCOCc1c[nH]cn1>>CNC(=S)NCCOCc1c[nH]cn1,,CC(C)O,,,,test
US20160096835A1,CCN(CC)S(=O)(=O)c1ccnc(Cl)c1.NN>>CCN(CC)S(=O)(=O)c1ccnc(NN)c1,,CCO,,,,test
US20120065195A1,CC1(C)CCc2ccc(Br)cc2C12COC(N)=N2.NC(=O)c1ccc(Cl)cn1>>CC1(C)CCc2ccc(NC(=O)c3ccc(Cl)cn3)cc2C12COC(N)=N2,[Cu]I,C1COCCO1,CO,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US05840732,CCCC=O.O=C1CSC(=O)N1Cc1cccc2nccn12>>CCCC=C1SC(=O)N(Cc2cccc3nccn23)C1=O,,CCO,,C1CCNCC1,,test
US20050080074A1,C/C=C\c1cc2c(c(C(F)(F)F)c1)C(=O)N1CCN(C(=O)OC(C)(C)C)C[C@@H]21.Cl>>C/C=C\c1cc2c(c(C(F)(F)F)c1)C(=O)N1CCNC[C@@H]21.Cl,,CCOCC,O,,,test
US20040048908A1,CCOC(=O)c1cnoc1-c1cc(Cl)ccc1Cl>>OCc1cnoc1-c1cc(Cl)ccc1Cl,,C1CCOC1,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20160168139A1,COCCN(CCOC)S(F)(F)F.O=c1cc(N2CCOCC2)cc(-c2cccc3c2Sc2ccc(NC(CO)CO)cc2S3)[nH]1>>O=c1cc(N2CCOCC2)cc(-c2cccc3c2Sc2ccc(N4CC4CF)cc2S3)[nH]1,,ClCCl,,O=C([O-])O.[Na+],,test
US20120245199A1,C#C[Si](C)(C)C.CCOC(=O)Nc1c(OC)ccnc1Br>>CCOC(=O)Nc1c(OC)ccnc1C#C[Si](C)(C)C,[Cu]I,C1CCOC1,,CCN(CC)CC,,test
US20130158006A1,COC(=O)c1ccc([N+](=O)[O-])c(OC)c1C.O=C1CCC(=O)N1Br>>COC(=O)c1ccc([N+](=O)[O-])c(OC)c1CBr,CC(C)(C#N)N=NC(C)(C)C#N,CC#N,,N#N,,test
US20090325988A1,BrBr.CS(=O)(=O)c1ccc(N)cn1>>CS(=O)(=O)c1ccc(N)c(Br)n1,,CC(=O)O,,[Na+].[OH-],,test
US20100311798A1,CON(C)C(=O)[C@H](CCC1CCCCC1)NC(=O)OC(C)(C)C.C[Mg]Cl>>CC(=O)[C@H](CCC1CCCCC1)NC(=O)OC(C)(C)C,,C1CCOC1,,,,test
US20060183762A1,COCC1(CO)CCN(Cc2ccccc2)C1.O=C1NC(=O)c2ccccc21>>COCC1(CN2C(=O)c3ccccc3C2=O)CCN(Cc2ccccc2)C1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040138277A1,CCOC(=O)C(C)(Oc1ccccc1OC)C(OC(=O)C(F)(F)F)c1ccc(OCc2ccccc2)cc1>>CCOC(=O)C(C)(Cc1ccc(O)cc1)Oc1ccccc1OC,[Pd],CCOC(C)=O,,,,test
US20110195954A1,O=C(c1cc(Cl)nc(Cl)c1)N1CCc2cc(F)ccc21.O=c1[nH]c2ncccc2n1C1CCNCC1>>O=C(c1cc(Cl)nc(N2CCC(n3c(=O)[nH]c4ncccc43)CC2)c1)N1CCc2cc(F)ccc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20030055044A1,Cc1cc(N)n[nH]1.ClC1=NC2(Cl)N=CN=C2C=N1>>Cc1cc(NC23N=CN=C2C=NC(Cl)=N3)n[nH]1,,CCO,,,,test
US20150166480A1,CCOC(=O)c1ccc(B(O)O)cc1F.FC(F)(F)C1(CN2CCC(COc3cnc(I)cn3)CC2)CCC1>>CCOC(=O)c1ccc(-c2cnc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)cn2)cc1F,,O,,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US20030114422A1,BrBr.CCOC(=O)C(=O)Nc1cccc2cccnc12>>CCOC(=O)C(=O)Nc1ccc(Br)c2cccnc12,,CC(=O)O,,,,test
US20080153905A1,C=O.N#CCc1ccccc1C(F)(F)F>>N#CC(CO)c1ccccc1C(F)(F)F,,C1CCOC1,O,C1CCC2=NCCCN2CC1,Cl,test
US20090186895A1,COCCOc1ccc(N)cc1-c1ccnn1C.O=C(Cl)c1cccc(Br)c1>>COCCOc1ccc(NC(=O)c2cccc(Br)c2)cc1-c1ccnn1C,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US06809199B2,CC(C)(C)OC(=O)N1CCC(c2cc3c(ccc(=O)n3-c3c(Cl)cccc3Cl)c(-c3ccccc3Cl)n2)CC1>>O=c1ccc2c(-c3ccccc3Cl)nc(C3CCNCC3)cc2n1-c1c(Cl)cccc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US05656629,CCc1[nH]n(C2CCCC2)c2nc(S(C)(=O)=O)nc(=O)c1-2.Oc1ccccc1>>CCc1[nH]n(C2CCCC2)c2nc(Oc3ccccc3)nc(=O)c1-2,,O,,[H-].[Na+],,test
US20140275172A1,COCBr.Oc1ccc2c(c1)OC(F)(F)O2>>COCOc1ccc2c(c1)OC(F)(F)O2,,C1CCOC1,,[H-].[Na+],,test
US20080255147A1,O=C(OCc1ccccc1)N1CCN(c2nc(-c3ccccc3F)cs2)CC1>>Fc1ccccc1-c1csc(N2CCNCC2)n1,,ClCCl,,BrB(Br)Br,,test
US05929072,CC(C)NCc1ccccc1N.NS(N)(=O)=O>>CC(C)N1Cc2ccccc2NS1(=O)=O,,c1ccncc1,,,,test
US20040138286A1,COc1c(OS(C)(=O)=O)ccc2c1cnn2C(C)=O>>COc1c(OS(C)(=O)=O)ccc2[nH]ncc12,,C1CCOC1,CO,O,[Li+].[OH-],test
US20090105211A1,Cc1cccc(C)c1N.O=C(O)c1ccc(Nc2nc(-c3ccc4[nH]ccc4c3)c3ccccc3n2)cc1>>Cc1cccc(C)c1NC(=O)c1ccc(Nc2nc(-c3ccc4[nH]ccc4c3)c3ccccc3n2)cc1,,CC(=O)N(C)C,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140135270A1,C=CCI.COC(=O)[C@@H]1CCC(=O)N1C(=O)OC(C)(C)C>>C=CC[C@H]1C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20010011094A1,Cc1cc(C)c(Nc2ccnc(Nc3ccc(C#N)cc3)n2)c(C)c1.Cl>>Cc1cc(C)c(Nc2ccnc(Nc3ccc(C#N)cc3)n2)c(C)c1.Cl,,CCO,,CC(C)O,,test
US04977162,N#Cc1cc(=O)c2ccc(CBr)cc2o1.Oc1cccc(OCc2ccc3ccccc3n2)c1>>N#Cc1cc(=O)c2ccc(COc3cccc(OCc4ccc5ccccc5n4)c3)cc2o1,,CS(C)=O,,O,[Na],test
US20130231328A1,CN(C(=O)OC(C)(C)C)C1(C)CCC(Oc2ncnc3sc4c(c23)[C@@H](CC#N)CC4)CC1.OO>>CN(C(=O)OC(C)(C)C)C1(C)CCC(Oc2ncnc3sc4c(c23)[C@@H](CC(N)=O)CC4)CC1,,CO,,O,[Li]O,test
US04645759,CC(C)CC(=O)Cl.CC(C)CC(NC(=O)OC(C)(C)C)C(O)CN>>CC(C)CC(=O)NCC(O)C(CC(C)C)NC(=O)OC(C)(C)C,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20070232590A1,Ic1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)cc1.O=C1CCCN1>>O=C1CCCN1c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)cc1,[Cu]I,C1COCCO1,,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US06610707B1,COC(=O)[C@@H]1CCCCN1.O=S(=O)(Cl)CC1CCCCC1>>COC(=O)[C@@H]1CCCCN1S(=O)(=O)CC1CCCCC1,,ClCCl,,CCN(CC)CC,Cl,test
US06627651B1,CCCOCCBr.OCc1ccc(O)cc1>>CCCOCCOc1ccc(CO)cc1,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20070116982A1,Ic1ccccc1-c1ccccc1.OB(O)c1cc(Br)cc(Br)c1>>Brc1cc(Br)cc(-c2ccccc2-c2ccccc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20110070192A1,CCOC(C)=O.Cc1ccc(S(=O)(=O)O)cc1.O=Cc1ccccc1.c1ccccc1>>C1=C[C@@H]2OC(c3ccccc3)OC[C@H]2OC1,,c1ccccc1,,,,test
US03975443,CN(Cc1ccccc1)C1(CN)CCCCC1.O=C(Cl)c1ccc(Cl)c(Cl)c1>>CN(Cc1ccccc1)C1(CNC(=O)c2ccc(Cl)c(Cl)c2)CCCCC1,,c1ccccc1,,,,test
US20150239900A1,COc1nc(N2CCN(C(=O)OC(C)(C)C)CC2)c2cc(Br)c(Cl)cc2n1.OB(O)c1ccc(Cl)cc1>>COc1nc(N2CCN(C(=O)OC(C)(C)C)CC2)c2cc(-c3ccc(Cl)cc3)c(Cl)cc2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20060094724A1,COC(=O)c1ccc2oc(C(=O)Nc3ccc(Cl)cn3)c(NC(=O)[C@@H]3CC[C@@H](N4CCOCC4=O)CC3)c2n1>>O=C(O)c1ccc2oc(C(=O)Nc3ccc(Cl)cn3)c(NC(=O)[C@@H]3CC[C@@H](N4CCOCC4=O)CC3)c2n1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20040077877A1,COCCOn1nc(-c2ccc(F)cc2)c2cc(N)ccc21.O=C=Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)Nc1ccc2[nH]nc(-c3ccc(F)cc3)c2c1,,C1COCCO1,,,,test
US20020045613A1,COc1ccc(Br)cn1.O=C(O)c1ccc(B(O)O)cc1>>COc1ccc(-c2ccc(C(=O)O)cc2)cn1,,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20140148459A1,C=CCOC(=O)C(CCO)SCc1ccc(-c2ccc(Cl)cc2)cc1.O=c1[nH]nnc2ccccc12>>C=CCOC(=O)C(CCn1nnc2ccccc2c1=O)SCc1ccc(-c2ccc(Cl)cc2)cc1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05804601,CCC(=O)Cl.COc1ccc(C(CCCCC(=O)NO)C2=C(C)C(=O)c3ccccc3C2=O)cc1>>CCC(=O)ONC(=O)CCCCC(C1=C(C)C(=O)c2ccccc2C1=O)c1ccc(OC)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20150210682A1,COc1ccc(CC(NC=O)C(F)(F)F)cc1OC>>COc1cc2c(cc1OC)CC(C(F)(F)F)N=C2,,CC#N,,O=P(Cl)(Cl)Cl,,test
US20100286442A1,CCC(CC)(C(=O)[O-])C(=O)[O-].CC[O-].ClC[C@@H]1CO1>>CCOC(=O)[C@@]12C[C@@H]1COC2=O,,O,,,,test
US04076812,C1=Cc2ccccc2Nc2ccccc21.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(N1c2ccccc2C=Cc2ccccc21)C(F)(F)F,,O,c1ccccc1,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20070265443A1,CCCCCCCCBr.c1csc(-c2cccs2)c1>>CCCCCCCCc1ccsc1-c1cccs1,,CCO,O,C1CCOC1,[Li]CCCC,test
US20060160901A1,CCCCc1cccc2c(S(=O)(=O)O)c(NC)ccc12.ClP(Cl)(Cl)(Cl)Cl>>CCCCc1cccc2c(S(=O)(=O)Cl)c(NC)ccc12,,CCOC(C)=O,,O,O=C([O-])O.[Na+],test
US20090264406A1,C[Si](C)(C)CCOCn1cc2cc(C(O)c3cnc4ccc(Cl)nn34)ccc2n1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cn1cc(-c2ccc3ncc(C(O)c4ccc5nn(COCC[Si](C)(C)C)cc5c4)n3n2)cn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20080214520A1,CC(=O)OC(C)=O.O=C(N1CCc2c(O)ccc(Br)c2CC1)C(F)(F)F>>CC(=O)Oc1ccc(Br)c2c1CCN(C(=O)C(F)(F)F)CC2,CN(C)c1ccncc1,,,c1ccncc1,,test
US20060079521A1,COC(=O)c1ccc(O)c2[nH]c(-c3ccccc3)nc12.O=C([O-])Oc1ccc([N+](=O)[O-])cc1>>OCc1ccc(OCc2ccccc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040167174A1,CC(=O)OC(C)=O.CCOc1cc(C(CC(=O)NO)N2C(=O)c3cccc(NC(C)=O)c3C2=O)ccc1OC>>CCOc1cc(C(CC(=O)NOC(C)=O)N2C(=O)c3cccc(NC(C)=O)c3C2=O)ccc1OC,,CC#N,,,,test
US20120208827A1,Cc1cccc([N+](=O)[O-])c1NC[C@@H]1CCN(C(=O)C2CC2)C1>>Cc1cccc(N)c1NC[C@@H]1CCN(C(=O)C2CC2)C1,[Pd],CO,,,,test
US20090105214A1,O=C(c1ccc(F)c(F)c1F)N(CCO)Cc1ccccc1>>O=C1c2ccc(F)c(F)c2OCCN1Cc1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US20030064962A1,BrCC=Cc1ccccc1.CC1C[C@@H](C(=O)Nc2ccccc2)n2c1ncc(N(Cc1cccc(C(F)(F)F)c1)C(=O)OCc1ccccc1)c2=O>>C[C@@]1(C/C=C/c2ccccc2)C[C@@H](C(=O)Nc2ccccc2)n2c1ncc(N(Cc1ccccc1)C(=O)OCc1ccccc1)c2=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20060211712A1,NC1CCOC1.O=[N+]([O-])c1ccccc1F>>O=[N+]([O-])c1ccccc1NC1CCOC1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20080096877A1,CCOC(=O)C(C)=NNc1ccc(O)cc1[N+](=O)[O-].CI>>CCOC(=O)C(C)=NNc1ccc(OC)cc1[N+](=O)[O-],,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20050209260A1,COc1cc(C(C)C)c(O)cc1-c1cscn1.N#CCBr>>COc1cc(C(C)C)c(OCC#N)cc1-c1cscn1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110212918A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCc1cc(N)cnc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2>>CC(C)(C)OC(=O)NCc1cc(N)cnc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2,,CO,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20050004095A1,Nc1nc(/C(=N/OC(c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)N[C@H]2C(=O)N3C(C(=O)OC(c4ccccc4)c4ccccc4)=C(Sc4nncs4)CCC23)c(Cl)s1>>Nc1nc(/C(=N/O)C(=O)N[C@H]2C(=O)N3C(C(=O)O)=C(Sc4nncs4)CCC23)c(Cl)s1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US06692797B1,COC(=O)Oc1ccc(C(=O)Oc2ccc3ccc(=O)oc3c2)cc1>>O=C(Oc1ccc2ccc(=O)oc2c1)c1ccc(O)cc1,,CCO,,N,,test
US20040186118A1,NC1CC1.Nc1ccc(Nc2ncc(Br)c(NCCc3cnc[nH]3)n2)cc1.S=C(c1ncc[nH]1)c1ncc[nH]1>>S=C(Nc1ccc(Nc2ncc(Br)c(NCCc3cnc[nH]3)n2)cc1)NC1CC1,,C1CCOC1,,CN(C)C=O,,test
US04743290,COCc1ccsc1S(N)(=O)=O.COc1cc(OC)nc(NC(=O)Oc2ccccc2)n1>>COCc1ccsc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1,,CC#N,,C1CCC2=NCCCN2CC1,Cl,test
US20140045872A1,Cc1ccncc1N1CCc2cc(F)c([N+](=O)[O-])cc2C1=O>>Cc1ccncc1N1CCc2cc(F)c(N)cc2C1=O,[Fe],C1CCOC1,,CC(=O)O,,test
US20110118231A1,COc1ccc(C=O)c(O)c1.C[N+](=O)[O-]>>COc1ccc(/C=C/[N+](=O)[O-])c(O)c1,,CC(=O)O,,C,O=C[O-].[NH4+],test
US20130045986A1,NC(=O)c1ccc(-c2ccc3oc(C4CCN(Cc5ccccc5)CC4)nc3c2)cc1F>>NC(=O)c1ccc(-c2ccc3oc(C4CCNCC4)nc3c2)cc1F,[Pd],CO,,,,test
US20100298337A1,CC(C)(C)c1cc(-c2cncc(Br)c2)nc(-c2ccccn2)n1.CN1CCN(Cc2ccc(B(O)O)cc2)CC1>>CN1CCN(Cc2ccc(-c3cncc(-c4cc(C(C)(C)C)nc(-c5ccccn5)n4)c3)cc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US20060094749A1,CC(C)(C)c1ccc(CCl)cc1.Cc1ncc(CNC(=O)c2ccc(C#N)cc2)c(CO)c1O>>Cc1ncc(CNC(=O)c2ccc(C#N)cc2)c(CO)c1OCc1ccc(C(C)(C)C)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130252937A1,CS(=O)(=O)Cl.Cc1cc(OCC(C)(C)CO)cc(C)c1Br>>Cc1cc(OCC(C)(C)COS(C)(=O)=O)cc(C)c1Br,,ClCCl,,CCN(CC)CC,,test
US20090298834A1,N[C@@H]1CC[C@@H](CNC(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1.O=Cc1ccccc1O>>O=C(NC[C@@H]1CC[C@@H](NCc2ccccc2O)CC1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20110105509A1,BrCc1ccccc1.Cc1[nH]c2ccc(Cl)cc2c1Cc1n[nH]c(=O)c2ccccc12>>Cc1[nH]c2ccc(Cl)cc2c1Cc1nn(Cc2ccccc2)c(=O)c2ccccc12,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04267180,Nc1ccc(-c2ncc(C(=O)O)c(O)n2)cc1.O=C1CC[C@@H](C(=O)O)N1>>O=C1CC[C@@H](C(=O)Nc2ccc(-c3ncc(C(=O)O)c(O)n3)cc2)N1,CCN(CC)CC,CN(C)C=O,ClCCl,O=S(Cl)Cl,,test
US20120225867A1,CCOC(=O)C(=O)CBr.NC(=S)c1c[nH]cn1>>CCOC(=O)c1csc(-c2c[nH]cn2)n1,,CCO,,,,test
US06200978B1,COc1cccc([C@@H](c2ccc3c(c2)CN(CC(=O)O)CC3)N2C[C@H](C)N(Cc3ccccc3)C[C@@H]2C)c1>>C[C@H]1CN([C@@H](c2cccc(O)c2)c2ccc3c(c2)CN(CC(=O)O)CC3)[C@@H](C)CN1Cc1ccccc1,,ClCCl,,BrB(Br)Br,,test
US03983142,CC1CC(=O)CC(C)(C)C1.NC1(OO)CCCCC1>>CC1CC(=O)CC(C)(C)C1.O=C1CCCCC1,,CO,,C,O=C[O-].[NH4+],test
US04624956,CN=C=S.Nc1nc2c(s1)CNCC2>>CNC(=S)N1CCc2nc(N)sc2C1,,CN(C)C=O,,,,test
US20090298878A1,CC(C)(C)[Si](C)(C)OCC(ON=C1CCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)CC1)c1cccc(C#N)c1>>N#Cc1cccc(C(CO)ON=C2CCN(S(=O)(=O)c3ccc(OC(F)(F)F)cc3)CC2)c1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20040071624A1,CC(C)(C)c1ccc(N)cc1.F[B-](F)(F)F.N#[O+]>>CC(C)(C)c1ccc([N+]#N)cc1.F[B-](F)(F)F,,CC#N,ClCCl,[Br-].[K+],,test
US20150291636A1,CC(C)[Si](OC[C@@H](OCc1ccccc1)[C@@H](OCc1ccccc1)[C@@H](CN(C=O)OCc1ccccc1)OCc1ccccc1)(C(C)C)C(C)C>>O=CN(C[C@@H](OCc1ccccc1)[C@H](OCc1ccccc1)[C@@H](CO)OCc1ccccc1)OCc1ccccc1,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080280906A1,C1COCCN1.O=C(O)c1ccc(Cl)cc1I>>O=C(c1ccc(Cl)cc1I)N1CCOCC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06861418B2,CC1(C)OB(c2cccc3[nH]ccc23)OC1(C)C.Fc1ccccc1Br>>Fc1ccccc1-n1ccc2ccccc21,[Pd],C1CCOC1,CCOC(C)=O,[Na+].[OH-],,test
US20110288066A1,CC(C)I.Cc1ccc(S)cc1Br>>Cc1ccc(SC(C)C)cc1Br,,CN(C)C=O,,[H-].[Na+],,test
US06071903,COC(=O)C(COC(C)=O)N(Cc1ccccc1N(C(C)=O)C(C)=O)S(=O)(=O)c1ccc(OC)cc1>>C=C(C(=O)OC)N(Cc1ccccc1N(C(C)=O)C(C)=O)S(=O)(=O)c1ccc(OC)cc1,,ClCCl,,CCN(CC)CC,,test
US20160251380A1,COB(OC)OC.O[C@H](CN(Cc1ccccc1)Cc1ccccc1)c1cccc(OCCOCc2ccccc2)c1>>OB1O[C@H](CN(Cc2ccccc2)Cc2ccccc2)c2cccc(OCCOCc3ccccc3)c21,,Cc1ccccc1,,Cl,[Li]CCCC,test
US20030195223A1,COC(=O)c1ccc(N)c(N)c1.N#Cc1cccc(C(=O)Cl)c1>>COC(=O)c1ccc(N)c(NC(=O)c2cccc(C#N)c2)c1,,CC#N,,c1ccncc1,,test
US20160068515A1,CS(=O)(=O)NCCBr.O=c1[nH]ncn1-c1ccc(Br)cc1F>>CS(=O)(=O)NCCn1ncn(-c2ccc(Br)cc2F)c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20030077701A1,COc1ccc(O[C@H](CCN2CC=C(c3ccc([N+](=O)[O-])cc3)CC2)c2ccccc2)cc1OC>>COc1ccc(O[C@H](CCN2CCC(c3ccc(N)cc3)CC2)c2ccccc2)cc1OC,[Pd],CCO,,[H][H],,test
US20090156583A1,ClCCCBr.O=C1NCCn2c1cc1cc(O)ccc12>>O=C1NCCn2c1cc1cc(OCCCCl)ccc12,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030199691A1,COCCl.CON(C)C(=O)c1cccc(O)c1>>COCOc1cccc(C(=O)N(C)OC)c1,,CN(C)C=O,,[H-].[Na+],,test
US20090221555A1,COc1cc2c(cc1[N+](=O)[O-])NC(=O)CN(Cc1ccccc1)C2.O=C(Cl)OCc1ccccc1>>COc1cc2c(cc1[N+](=O)[O-])NC(=O)CN(C(=O)OCc1ccccc1)C2,,ClCCCl,,,,test
US20120232061A1,COc1ccc(-c2ccc3c(c2)CCN(C(=O)OC(C)(C)C)CC3)c(OCc2cc(C)ccn2)c1>>COc1ccc(-c2ccc3c(c2)CCNCC3)c(OCc2cc(C)ccn2)c1,,C1COCCO1,,Cl,,test
US20080085890A1,COCOc1cc(C#N)ccc1-c1cccc(CN(C)C)c1>>COCOc1cc(CN)ccc1-c1cccc(CN(C)C)c1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05208247,CCCCCCCCCCCCCCBr.COC(=O)c1ccc(O)c(C(C)(C)C)c1>>CCCCCCCCCCCCCCOc1ccc(C(=O)OC)cc1C(C)(C)C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110034469A1,C[C@@H](C(=O)N[C@H](C(=O)N1C[C@H]2CC(F)(F)CN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCOCC1)N(C)C(=O)OC(C)(C)C>>CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H]2CC(F)(F)CN2C[C@H]1C(=O)N[C@@H]1CCOc2ccccc21)C1CCOCC1,,CCOC(C)=O,,Cl,,test
US20100087418A1,CC(C)(C)OC(=O)N1CCOc2c(cccc2-c2ccccc2Cl)C1.Cl>>Cl.Clc1ccccc1-c1cccc2c1OCCNC2,,CCOC(C)=O,,,,test
US20100190782A1,COC(=O)c1nc(-c2ccc3c(c2)N(C(=O)Nc2nc4ccccc4s2)CCC3)ccc1-c1ccccc1>>O=C(O)c1nc(-c2ccc3c(c2)N(C(=O)Nc2nc4ccccc4s2)CCC3)ccc1-c1ccccc1,,CO,O,[Li+].[OH-],,test
US20150065468A1,Brc1cnc2sccc2c1.CC1(C)OB(c2ccc(CC(=O)Nc3cc(C4(C(F)(F)F)CC4)on3)cc2)OC1(C)C>>O=C(Cc1ccc(-c2cnc3sccc3c2)cc1)Nc1cc(C2(C(F)(F)F)CC2)on1,,O,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US20160000760A1,Nc1ccc(-c2ccccc2F)c(Cl)c1.S=C(n1ccnc1)n1ccnc1>>Fc1ccccc1-c1ccc(N=C=S)cc1Cl,,ClCCl,,,,test
US06048864,CC(=O)N1CCCN(C(=O)N2CCOCC2)CC1.COc1cc(N)c(C#N)cc1OCc1ccccc1>>COc1cc(N=C(C)N2CCCN(C(=O)N3CCOCC3)CC2)c(C#N)cc1OCc1ccccc1,,ClCCl,,O=P(Cl)(Cl)Cl,,test
US20150344427A1,C1CCNC1.COc1cc(C)nc(Cl)c1C#N>>COc1cc(C)nc(N2CCCC2)c1C#N,,CC#N,O,CCN(C(C)C)C(C)C,,test
US20130131040A1,Cn1ccc2c(Nc3nc(N[C@@H]4CCCC[C@@H]4NC(=O)OC(C)(C)C)cnc3C#N)cccc21>>Cn1ccc2c(Nc3nc(N[C@@H]4CCCC[C@@H]4N)cnc3C#N)cccc21,,O=C(O)C(F)(F)F,,,,test
US20090270451A1,BrCC1CC1.CC(C)(C)OC(=O)N1CCC(C#N)CC1>>CC(C)(C)OC(=O)N1CCC(C#N)(CC2CC2)CC1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20130109667A1,CC(C)(C)OC(=O)N(c1cscn1)S(=O)(=O)c1cc(Cl)c(F)cc1F.Oc1cc(F)c(C(F)(F)F)cc1-c1ccnnc1>>O=S(=O)(Nc1cscn1)c1cc(Cl)c(Oc2cc(F)c(C(F)(F)F)cc2-c2ccnnc2)cc1F,,CS(C)=O,O,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20130018010A1,CC(C)(N)C(=O)O.N#Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12.N#Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12.O=C(O)C(F)(F)F>>CC(C)(N)C(=O)O.N#Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12.NC(=O)[O-],CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100160303A1,Cc1c(Br)cccc1N1C(=O)Cc2ccccc2C1=O>>Cc1c(Br)cccc1N1C(=O)c2ccccc2CC1O,,CO,,[BH4-].[Na+],,test
US20150376136A1,CCOC(=O)C(C)C1CCCCC1.N#CCBr>>CCOC(=O)C(C)(CC#N)C1CCCCC1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US05519024,CCOC(=O)c1cnc2c(F)c(F)c(F)cc2c1O.ClCc1cscn1>>CCOC(=O)c1cn(Cc2cscn2)c2c(F)c(F)c(F)cc2c1=O,,CN(C)C=O,,Cl,[H-].[Na+],test
US05498799,CC(C)(C)[C@H]1OC(=O)[C@](C)(Br)O1>>C=C1O[C@H](C(C)(C)C)OC1=O,,ClC(Cl)(Cl)Cl,,CCN(CC)CC,,test
US20150376207A1,N#Cc1ccc(B(O)O)cc1.O=C(NC1=N[C@@]2(c3ccc(F)cc3F)COC(OS(=O)(=O)C(F)(F)F)=C[C@H]2CS1)c1ccccc1>>N#Cc1ccc(C2=C[C@H]3CSC(NC(=O)c4ccccc4)=N[C@@]3(c3ccc(F)cc3F)CO2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130331375A1,Cc1ccc(S(=O)(=O)OCC(C)(C#N)c2ccc(Br)cc2)cc1>>CC1(c2ccc(Br)cc2)CNC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150203511A1,COc1cc(-c2ccc(OC(C)C)c(C)c2)nn1C.O=C1CCC(=O)N1Cl>>COc1c(Cl)c(-c2ccc(OC(C)C)c(C)c2)nn1C,,O,,ClC(Cl)Cl,,test
US20140179720A1,COCCOc1ccc(Nc2ncc(F)c(Nc3cc([N+](=O)[O-])ccc3OCc3ccccc3)n2)cc1>>COCCOc1ccc(Nc2ncc(F)c(Nc3cc(N)ccc3O)n2)cc1,[Pd],C1CCOC1,CO,,,test
US20050245527A1,CC(C)(C)Oc1nccnc1CN1CCC(C(C#N)Cc2ccccc2F)CC1>>N#CC(Cc1ccccc1F)C1CCN(Cc2ncc[nH]c2=O)CC1,,CCOC(C)=O,,Cl,[Na+].[OH-],test
US20140296226A1,COc1nc(C2=CCOCC2)cc2c1Oc1ccc(N)cc1[C@@]21CCOC(N)=N1.O=C(O)c1ccc(Cl)cn1>>COc1nc(C2=CCOCC2)cc2c1Oc1ccc(NC(=O)c3ccc(Cl)cn3)cc1[C@@]21CCOC(N)=N1,,C1CCOC1,CO,COc1nc(OC)nc([N+]2(C)CCOCC2)n1.[Cl-],,test
US20150038488A1,COc1ccc([C@@H](C)N2C[C@H]([C@@H](C)Oc3cc(-c4ccc(N5CCN(C(=O)OC(C)(C)C)CC5)cc4)cn4nccc34)CC2=O)cc1>>C[C@@H](Oc1cc(-c2ccc(N3CCNCC3)cc2)cn2nccc12)[C@H]1CNC(=O)C1,,O=C(O)C(F)(F)F,,,,test
US20020002163A1,Nc1c(Cl)cccc1C(=O)c1ccccc1F.O=C(Br)CBr>>O=C(CBr)Nc1c(Cl)cccc1C(=O)c1ccccc1F,,CCOC(C)=O,ClCCl,c1ccncc1,,test
US04855292,CCO.N#CCc1c(F)ccc(F)c1F.O=S(=O)(O)O>>CCOC(=O)Cc1c(F)ccc(F)c1F,,CCO,,CCOCC,O,test
US20050009109A1,CCCCC(CC)CBr.Cc1cc(=O)cc(C)n1-c1cccc(O)c1>>CCCCC(CC)COc1cccc(-n2c(C)cc(=O)cc2C)c1,,CN1CCCC1=O,O,Cl,[I-].[K+],test
US20110136795A1,CCOC(=O)Cc1c(F)cnc2ccc(OC)nc12.O=C1c2ccccc2C(=O)N1CBr>>CCOC(=O)C(CN1C(=O)c2ccccc2C1=O)c1c(F)cnc2ccc(OC)nc12,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05106839,CCOC(=O)Cl.Clc1ccc2c(c1)OCCN(Cc1ccccc1)CCc1ccccc1O2>>CCOC(=O)N1CCOc2cc(Cl)ccc2Oc2ccccc2CC1,,Cc1ccccc1,,Cl,,test
US20050043544A1,CCOC(=O)C[Zn]Br.O=C1C=C(Cl)C(=O)C(Cl)=C1>>CCOC(=O)CC1(O)C=C(Cl)C(=O)C(Cl)=C1,,C1CCOC1,,CCOC(C)=O,Cl,test
US07662581B1,Nc1ccc(Br)cc1[N+](=O)[O-].O=Cc1ccccc1>>O=[N+]([O-])c1cc(Br)ccc1NCc1ccccc1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140329825A1,CN(Cc1ccncc1)c1ncc(C#N)cn1.NO>>CN(Cc1ccncc1)c1ncc(C(N)=NO)cn1,,CCO,,CCN(CC)CC,Cl,test
US20130034616A1,CC(C)(C)[Si](C)(C)Cl.O=C1OC(CCO)c2ccccc21>>CC(C)(C)[Si](C)(C)OCCC1OC(=O)c2ccccc21,,C1CCOC1,,c1c[nH]cn1,,test
US03996374,CCN(CC)CCCl.CCOC(=O)c1[nH]c(-c2ccccc2)c2ccccc12.Cl>>CCOC(=O)c1c2ccccc2c(-c2ccccc2)n1CCN(CC)CC.Cl,,CN(C)C=O,,[H-].[Na+],,test
US20120238541A1,CN(C)C=O.COc1cccnc1Cl>>COc1c(C=O)ccnc1Cl,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20130281438A1,CCCNS(=O)(=O)c1ccccc1[N+](=O)[O-]>>CCCNS(=O)(=O)c1ccccc1N,[Pd],CO,,,,test
US20130338140A1,CCOC(=O)[C@H]1CCc2c(Cl)nc(NC3CCOCC3)nc2O1>>CCOC(=O)[C@H]1CCc2cnc(NC3CCOCC3)nc2O1,[Pd],CCOC(C)=O,,,,test
US20140275007A1,CC(C)(C)OC(=O)CON.O=C(O)C(=O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>CC(C)(C)OC(=O)CO/N=C(\C(=O)O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,ClCCl,,,,test
US20070197617A1,C[C@@H](c1ccccc1)[C@@H](C(=O)Nc1ccc(I)cc1F)N1C(=O)N[C@H](c2ccc(OC[C@H](O)CO)cc2)C1=O>>C[C@@H](c1ccccc1)[C@@H](C(=O)Nc1ccc(I)cc1F)N1C(=O)N[C@@H](c2ccc(OC[C@H](O)CO)cc2)C1=O,,CO,,,,test
US20140080825A1,COc1ccccc1CC(O)c1cnc(NC(=O)OC(C)(C)C)s1.O=C(O)C(F)(F)F>>COc1ccccc1CCc1cnc(N)s1.O=C(O)C(F)(F)F,,ClCCl,,CC[SiH](CC)CC,,test
US05446023,CCCCCCCCCCCNC(=O)C(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C>>N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120108572A1,B1C2CCCC1CCC2.C=C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(CB2C3CCCC2CCC3)CC1,,C1CCOC1,,,,test
US20070060607A1,CCOC(=O)c1cnc(N)c2c(COc3cccc(NC(=O)c4cccc(OCCN5CCOCC5)c4)c3)csc12.NCCO>>Nc1ncc(C(=O)NCCO)c2scc(COc3cccc(NC(=O)c4cccc(OCCN5CCOCC5)c4)c3)c12,,CS(C)=O,,,,test
US05409939,CSCCC(CC(=O)O)NC(=O)CCCCc1ccc(C=NN)cc1.OO>>CS(=O)(=O)CCC(CC(=O)O)NC(=O)CCCCc1ccc(C=NN)cc1,,CC(=O)O,,O,,test
US20120316147A1,CO.Cc1ccc(C(=O)O)nc1S(=O)(=O)O>>COC(=O)c1ccc(C)c(S(=O)(=O)O)n1,,C1COCCO1,,Cl,,test
US20130225552A1,COc1nc2cccnc2n1C1CC(C(=O)c2nc3ccccc3[nH]2)C1>>COc1nc2cccnc2n1C1CC(C(O)c2nc3ccccc3[nH]2)C1,,C1CCOC1,,[BH4-].[Na+],,test
US20130336920A1,CCN(CC)c1ccc(NC(=O)c2cccc(C(=O)N(C)CCOCCOCCOCCC(=O)OC(C)(C)C)c2)c(-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1>>CCN(CC)c1ccc(NC(=O)c2cccc(C(=O)N(C)CCOCCOCCOCCC(=O)O)c2)c(-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090306041A1,CC(=O)OCc1c(Br)cccc1Br.CCN(C)c1ccc2c(c1)CCNC2=O>>CCN(C)c1ccc2c(c1)CCN(c1cccc(Br)c1COC(C)=O)C2=O,,CCOC(C)=O,O,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20140051679A1,CC1(C)OB(c2ccc(CCN3CCOCC3)cc2)OC1(C)C.O=C(Nc1ccc2[nH]nc(I)c2c1)C(c1ccsc1)N1CCCC1>>O=C(Nc1ccc2[nH]nc(-c3ccc(CCN4CCOCC4)cc3)c2c1)C(c1ccsc1)N1CCCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20110275628A1,CC(C)(C)N(c1cccc2c1ccn2C(C)(C)C)C(C)(C)C.CC(C)OB(OC(C)C)OC(C)C>>CC(C)(C)N(c1cccc2c1cc(B(O)O)n2C(C)(C)C)C(C)(C)C,,C1CCOC1,,Cl,CC(C)[N-]C(C)C.[Li+],test
US06683029B1,Fc1ncc(F)c(F)n1.Oc1cccc(F)c1>>Fc1cccc(Oc2ncc(F)c(F)n2)c1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20070105919A1,CC(C)[Si](C(C)C)(C(C)C)n1ccc(C(=O)c2sc(NC(=O)c3ccncc3)nc2-c2ccco2)c1>>O=C(Nc1nc(-c2ccco2)c(C(=O)c2cc[nH]c2)s1)c1ccncc1,,CCO,,Cl,O=C([O-])O.[Na+],test
US20110065725A1,CCOC(=O)c1nnn(-c2ccc(F)c(F)c2)c1C.Cc1cc(N)ccn1>>Cc1cc(NC(=O)c2nnn(-c3ccc(F)c(F)c3)c2C)ccn1,,C1COCCO1,,C[Al](C)C,,test
US20040010022A1,COC(=O)CBr.Nc1nc(-c2c(O)ccc3ccccc23)co1>>COC(=O)COc1ccc2ccccc2c1-c1coc(N)n1,,CN(C)C=O,,[H-].[Na+],,test
US20080171734A1,Fc1ccc(SCCCOC2CCCCO2)c(F)c1>>OCCCSc1ccc(F)cc1F,,CO,,Cl,,test
US20110294812A1,Nc1nccc(COc2ccc([N+](=O)[O-])c3ccccc23)n1>>Nc1nccc(COc2ccc(N)c3ccccc23)n1,[Pt],CC(=O)O,ClCCl,[H][H],,test
US05621133,CCOC=O.COc1ccc2c(c1OC)CC(c1ccccc1)C1=C2CNCC1>>COc1ccc2c(c1OC)CC(c1ccccc1)C1=C2CN(C=O)CC1,,C1CCOC1,,,,test
US20150368269A1,Cc1ccc(N2CCO[C@H]([C@@H](O)C(=O)Nc3ccc(C#N)cc3C(N)=O)C2=O)cc1>>Cc1ccc(N2CCO[C@H]([C@@H](O)c3nc(=O)c4cc(C#N)ccc4[nH]3)C2=O)cc1,,C1COCCO1,CCOC(C)=O,[Na+].[OH-],,test
US04066772,O=c1[nH]c2ccccc2n1CCCCCl.OC1(c2ccc(Cl)cc2)CCNCC1>>O=c1[nH]c2ccccc2n1CCCCN1CCC(O)(c2ccc(Cl)cc2)CC1,,CC(=O)CC(C)C,O,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US20160168139A1,CCNCC.COC(=O)c1cnc(Cl)cn1>>COC(=O)c1cnc(N(C)C)cn1,,C1COCCO1,,CO,,test
US09073882B2,Cc1cc(CC=O)ccc1C#N.O=[N+]([O-])c1ccc(CCN2CCNCC2)cc1>>Cc1cc(CCN2CCN(CCc3ccc([N+](=O)[O-])cc3)CC2)ccc1C#N,CC(=O)O,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130211075A1,Cc1cc(NC(=O)c2cnn(-c3ccc(C(F)(F)F)cn3)c2C)cnc1[C@@H]1CC[C@@H](O[Si](C)(C)C(C)(C)C)CC1>>Cc1cc(NC(=O)c2cnn(-c3ccc(C(F)(F)F)cn3)c2C)cnc1[C@@H]1CC[C@@H](O)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100168418A1,CCC(O)c1cc(OC)cc2c1ccc(=O)n2CCN1CCC(N(Cc2ccc3c(c2)OCCO3)C(=O)OC(C)(C)C)CC1>>CCC(=O)c1cc(OC)cc2c1ccc(=O)n2CCN1CCC(N(Cc2ccc3c(c2)OCCO3)C(=O)OC(C)(C)C)CC1,,ClC(Cl)Cl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US20150152118A1,Fc1ccc(N2CC3CCC(C2)N3Cc2ccccc2)cc1>>Fc1ccc(N2C[C@@H]3CC[C@H](C2)N3)cc1,[Pd],CO,,,,test
US20130029964A1,CCOC(=O)CP(=O)(OCC(F)(F)F)OCC(F)(F)F.CCOC(=O)Cn1nccc1C=O>>CCOC(=O)c1c(O)ccc2ccnn12,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20070105904A1,Brc1ccc(Oc2ccccc2)nc1.CN(C)C=O>>O=Cc1ccc(Oc2ccccc2)nc1,,C1CCOC1,,[Li]CCCC,,test
US20030144283A1,CCc1nc2c(N)nc3ccccc3c2n1CCCCN.O=C(Cl)C1CCCC1>>CCc1nc2c(N)nc3ccccc3c2n1CCCCNC(=O)C1CCCC1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20070179191A1,COc1ccc(-c2nc(COC3CCCCO3)c(CO)o2)cc1.CS(=O)(=O)Cl>>COc1ccc(-c2nc(COC3CCCCO3)c(CCl)o2)cc1,,ClCCl,,CCN(CC)CC,,test
US20130225552A1,CCOC([O-])[O-].Nc1cccnc1N[C@@H]1C[C@@H](Nc2nc3ccccc3s2)C1>>c1ccc2sc(N[C@@H]3C[C@@H](n4cnc5cccnc54)C3)nc2c1,,CC(=O)O,,,,test
US20020010176A1,CCOC(=O)C[C@H](NCc1ccc2c(n1)NCCC2)c1cccc(F)c1>>O=C(O)C[C@H](NCc1ccc2c(n1)NCCC2)c1cccc(F)c1,,CCO,,Cl,[Na+].[OH-],test
US20100081653A1,N#CC(=C1Nc2ccc([N+](=O)[O-])cc2S1)c1nccc(C(F)(F)F)n1.O=S(=O)(O)O>>NC(=O)C(=C1Nc2ccc([N+](=O)[O-])cc2S1)c1nccc(C(F)(F)F)n1,,O=S(=O)(O)O,,O,,test
US20100048648A1,C=CCOc1c(C)cc(C(=O)NN)cc1C.CC(C)Cc1ccc(C(=O)O)s1>>C=CCOc1c(C)cc(C(=O)NNC(=O)c2ccc(CC(C)C)s2)cc1C,,CCOCC,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20090318408A1,Cc1cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C>>Cc1cc(C(=O)NC2CCNCC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C,,ClCCl,,O=C(O)C(F)(F)F,,test
US04363807,CC(=O)OC(C)=O.O=C(Cc1ccccc1)NC1C(=O)N2C(C(=O)O)C(CO)CS[C@H]12>>CC(=O)OC=C1CS[C@@H]2C(NC(=O)Cc3ccccc3)C(=O)N2C1C(=O)O,,CS(C)=O,,,,test
US20070293515A1,Cc1ccc(C(N)=NO)cc1.O=C(OC(=O)C(Cl)(Cl)Cl)C(Cl)(Cl)Cl>>Cc1ccc(-c2noc(C(Cl)(Cl)Cl)n2)cc1,,Cc1ccccc1,,O,,test
US20050085638A1,NC1CC1.Nc1nc(Cl)c2ncn([C@H]3CO[C@@H](COC(=O)c4ccccc4)O3)c2n1>>Nc1nc(NC2CC2)c2ncn([C@H]3CO[C@@H](COC(=O)c4ccccc4)O3)c2n1,,CCO,,,,test
US05108485,C=[N+]=[N-].Cc1nc2c(C3=NC(C)(C(C)C)C(=O)N3)c(C(=O)O)ccc2n1Cc1ccccc1>>COC(=O)c1ccc2c(nc(C)n2Cc2ccccc2)c1C1=NC(C)(C(C)C)C(=O)N1,,CCOCC,CO,,,test
US20110301155A1,O=[N+]([O-])c1cc[nH]n1.OCCCl>>O=[N+]([O-])c1ccn(CCO)n1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20060030613A1,CC(C)(C)c1ccc(CN(CCO)C(=O)c2cccc3cc[nH]c23)cc1.Oc1ccc(F)cc1>>CC(C)(C)c1ccc(CN(CCOc2ccc(F)cc2)C(=O)c2cccc3cc[nH]c23)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090324581A1,N#CCOc1ccc(Cl)cc1.O=[N+]([O-])c1ccc(OCc2ccccc2)c(F)c1>>N#CCc1cc(OCc2ccccc2)c(F)cc1[N+](=O)[O-],,CN(C)C=O,,Cl,CC(C)(C)[O-].[K+],test
US20080200525A1,CC(=O)Cc1ccc(OCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1.CC(C)CCON=O>>CC(=O)C(=NO)c1ccc(OCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1,,C1COCCO1,O,CCN(CC)CC,Cl,test
US20050288346A1,CC(=O)c1ccc(O)c(Br)c1O.N#Cc1ccc(OCCCCBr)cc1>>CC(=O)c1ccc(OCCCCOc2ccc(C#N)cc2)c(Br)c1O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06756380B1,CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1nc(S(C)(=O)=O)ncc1-c1ccccc1.N>>CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1nc(N)ncc1-c1ccccc1,,CN(C)C=O,,O,,test
US20070213323A1,COC(=O)Cl.O=c1ccc(-c2ccc(O)cc2)cn1Cc1ccc(Cl)cc1F>>COC(=O)Oc1ccc(-c2ccc(=O)n(Cc3ccc(Cl)cc3F)c2)cc1,,C1CCOC1,,O,O=C([O-])[O-].[K+].[K+],test
US04011319,COc1ccc(CCN(Cc2ccccc2)CC(O)c2ccc(Cl)cc2)cc1OC.Cl>>COc1ccc(CCNCC(O)c2ccc(Cl)cc2)cc1OC.Cl,[Pd],CO,,CCOC(C)=O,,test
US05714489,O=c1[nH]c2cc(C(F)(F)F)c([N+](=O)[O-])cc2n(C2CCCCC2)c1=O>>Nc1cc2c(cc1C(F)(F)F)[nH]c(=O)c(=O)n2C1CCCCC1,[Pd],C1CCOC1,,[H][H],,test
US20110152262A1,N[C@@H](C(=O)O)C1Cc2ccccc2C1.O=C(OCc1ccccc1)ON1C(=O)CCC1=O>>O=C(N[C@@H](C(=O)O)C1Cc2ccccc2C1)OCc1ccccc1,,C1COCCO1,O,CCN(CC)CC,,test
US05942511,C=CCS.COc1nnc(Cl)c(C)c1C>>C=CCSc1nnc(OC)c(C)c1C,,CO,,[Na],,test
US20160002177A1,ClI.Nc1c(OCc2ccccc2)cccc1C(=O)OCc1ccccc1>>Nc1c(OCc2ccccc2)cc(I)cc1C(=O)OCc1ccccc1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US04005217,CNC.COC(=O)Nc1ccc(NC(=O)CBr)c([N+](=O)[O-])c1>>COC(=O)Nc1ccc(NC(=O)CN(C)C)c([N+](=O)[O-])c1,,CCO,,,,test
US05861401,COc1nc(Br)cnc1N.O=S(=O)(Cl)c1ccccc1-c1ccccc1>>COc1nc(Br)cnc1NS(=O)(=O)c1ccccc1-c1ccccc1,,COCCOC,O,Cl,[H-].[Na+],test
US20090099156A1,CC(C)(C)N1CCN(Cc2ccccc2)CC1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCN(C(C)(C)C)CC1,[Pd],CCO,,,,test
US20080262064A1,COc1ccc(COC(C)(C)CO)cc1.Oc1ccccc1>>COc1ccc(COC(C)(C)COc2ccccc2)cc1,,Cc1ccccc1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04960766,CC(=O)C(=NO)C(=O)OC(C)(C)C.Nc1ccccc1>>CC(=Nc1ccccc1)C(=NO)C(=O)OC(C)(C)C,,c1ccccc1,,CC(=O)O,O,test
US20050131017A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C[C@@H]1OC(C)(C)N(C(=O)OCc2ccccc2)[C@H]1Cc1ccc(-c2ccncc2)cc1>>N[C@@H](Cc1ccccc1)C[C@H](O)[C@H](Cc1ccc(-c2ccncc2)cc1)NC(=O)OCc1ccccc1,,C1CCOC1,,CO,Cl,test
US20160159752A1,COc1ccc([C@H](c2ccc(Cl)cc2)[C@H](N=[N+]=[N-])C(=O)N2C(=O)OC[C@@H]2c2ccccc2)cn1.OO>>COc1ccc([C@@H](c2ccc(Cl)cc2)[C@H](N=[N+]=[N-])C(=O)O)cn1,,C1CCOC1,O,[Li+].[OH-],,test
US20020052521A1,C[C@H](N)c1ccccc1.ClP(Cl)(Cl)(Cl)Cl>>C[C@H](N=P(Cl)(Cl)Cl)c1ccccc1,,ClC(Cl)(Cl)Cl,,,,test
US06057264,CCCCCCCN1c2ccccc2CC1(C)C.CN(C)C=O>>CCCCCCCN1c2ccc(C=O)cc2CC1(C)C,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US04810713,CCOC(=O)Nc1ccc(O)cc1.ClCCCBr>>CCOC(=O)Nc1ccc(OCCCCl)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110123493A1,CC(C)(C)N.Cc1ccc(S(=O)(=O)Cl)c(F)c1>>Cc1ccc(S(=O)(=O)NC(C)(C)C)c(F)c1,,C1CCOC1,,,,test
US20140088111A1,CC(=O)O[BH-](OC(C)=O)OC(C)=O.CCN(CC)CC.ClCCCl.ClCCl.N[C@@H]1CCC[C@H]1O.O=Cc1ccccc1>>O[C@@H]1CCC[C@H]1N(Cc1ccccc1)Cc1ccccc1,,ClCCl,,Cl,,test
US20040235892A1,Cc1cccc(N=C=O)c1.Nc1ccc(Br)cc1F>>Cc1cccc(NC(=O)Nc2ccc(Br)cc2F)c1,,ClCCl,,,,test
US06943184B2,COC(=O)CC1(N(C)C)CC1.Cl>>CN(C)C1(CCO)CC1.Cl,,C1CCOC1,C1COCCO1,O,[Na+].[OH-],test
US20120232090A1,Clc1ncnc2c1nc(-c1ccccc1)n2-c1ccccc1.NCCCO>>OCCCNc1ncnc2c1nc(-c1ccccc1)n2-c1ccccc1,,C1COCCO1,,,,test
US04368205,CC(=O)Cl.O=[N+]([O-])c1cccc2c1CCC2O>>CC(=O)OC1CCc2c1cccc2[N+](=O)[O-],,Cc1ccccc1,,c1ccncc1,,test
US20020173507A1,C1COCCN1.O=Cc1cccc(Br)n1>>Cc1ccc(N2CCOCC2)nc1Br,,CC(Cl)Cl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20150291636A1,CCOP(=O)(OCC)C(O)C[C@@H](O)[C@@H](O)[C@@H](O)CNOCc1ccccc1.O=COCC(F)(F)F>>CCOP(=O)(OCC)C(O)C[C@@H](O)[C@@H](O)[C@@H](O)CN(C=O)OCc1ccccc1,,C1CCOC1,,CO,ClCCl,test
US20150291549A1,Cc1cc(OCc2cccc(-c3ccc4c(c3)OCCO4)c2C)cc(O)c1C=O.N#Cc1cccc(CBr)c1>>Cc1cc(OCc2cccc(-c3ccc4c(c3)OCCO4)c2C)cc(OCc2cccc(C#N)c2)c1C=O,,CCOC(C)=O,CN(C)C=O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20030087901A1,COc1ccc2c(c1)CCNC2Cc1ccc(OCc2ccccc2)cc1.O=C(Cl)c1ccccc1>>COc1ccc2c(c1)CCN(C(=O)c1ccccc1)C2Cc1ccc(OCc2ccccc2)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20060276433A1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1ccc(F)c(I)c1>>CC(C)(C)OC(=O)N1CCN(c2ccc(C=O)cc2I)CC1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US08629147B2,CCOC(=O)C(F)(F)Br.Cc1cc(I)cc([N+](=O)[O-])c1N>>CCOC(=O)C(F)(F)c1cc(C)c(N)c([N+](=O)[O-])c1,[Cu],CS(C)=O,,,,test
US20150031674A1,CS(=O)(=O)Cl.O=C(OCc1ccccc1)N1CC2(C1)OCC(CO)CO2>>CS(=O)(=O)OCC1COC2(CN(C(=O)OCc3ccccc3)C2)OC1,,CCOC(C)=O,,ClCCl,,test
US20150191483A1,CC(C)(C)OC(=O)N1CCC(O)(C(=O)N2CC[C@](c3ccc(C(OCc4c(F)cccc4F)(C(F)(F)F)C(F)(F)F)cc3)(S(=O)(=O)c3ccc(F)cc3)C2)CC1.Cl>>Cl.O=C(N1CC[C@](c2ccc(C(OCc3c(F)cccc3F)(C(F)(F)F)C(F)(F)F)cc2)(S(=O)(=O)c2ccc(F)cc2)C1)C1(O)CCNCC1,,ClCCl,,C1COCCO1,,test
US20060235033A1,COc1cc2nccc(Oc3cc(C)c(N)cc3C)c2cc1OC.C[C@H](N)c1nccs1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3cc(C)c(NC(=O)N[C@@H](C)c4nccs4)cc3C)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20070049571A1,CC(C)(C)OC(=O)NC1CCN(CC(=O)N2CCN(C3CCC3)CC2)CC1>>NC1CCN(CC(=O)N2CCN(C3CCC3)CC2)CC1,,C1COCCO1,ClCCl,Cl,,test
US20100004280A1,CN(C)S(=O)(=O)n1cc(CC(C)(C)C)nc1C(C)(O)Cc1ccc(-c2ccc(F)cn2)cc1F>>CC(C)(C)Cc1c[nH]c(C(C)(O)Cc2ccc(-c3ccc(F)cn3)cc2F)n1,,CO,,Cl,,test
US20100009975A1,CC(C)(C)OC(=O)N1CCC(Nc2cc([N+](=O)[O-])ccc2Cl)CC1.OCCS>>CC(C)(C)OC(=O)N1CCC(Nc2cc([N+](=O)[O-])ccc2SCCO)CC1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04125732,COC(=O)C(Br)c1ccc(OCCOc2ccc(F)cc2)cc1.Cc1ccc(O)cc1C>>COC(=O)C(Oc1ccc(C)c(C)c1)c1ccc(OCCOc2ccc(F)cc2)cc1,,C1CCOC1,,,,test
US20160016979A1,O=C1C=CC(c2ccccc2)(c2ccccc2)CC1>>OC1CCC(c2ccccc2)(c2ccccc2)CC1,[Ni],C1CCOC1,,,,test
US20100216746A1,CC(C)(C)OC(=O)Nc1ccc2[nH]c(C(=O)O)c(Cl)c2c1.N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CN)c2F)c1>>CC(C)(C)OC(=O)Nc1ccc2[nH]c(C(=O)NCc3ccc(Cl)c(Oc4cc(Cl)cc(C#N)c4)c3F)c(Cl)c2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140142083A1,CCI.COC(=O)c1cc(Cl)cc(NCC2CCCC2)c1C>>CCN(CC1CCCC1)c1cc(Cl)cc(C(=O)OC)c1C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06498172B1,COC(=O)CCCCCCNCc1ccc(-c2nccs2)cc1.Cn1cnc(S(=O)(=O)Cl)c1>>COC(=O)CCCCCCN(Cc1ccc(-c2nccs2)cc1)S(=O)(=O)c1cn(C)cn1,,CCN(CC)CC,,,,test
US20050228003A1,CCCC(=O)Cl.COC(=O)c1sccc1N>>CCCC(=O)Nc1ccsc1C(=O)OC,,ClCCl,,c1ccncc1,,test
US20090306066A1,CN1C(=O)CCN1C(=O)OC(C)(C)C>>CN1CCCN1C(=O)OC(C)(C)C,,ClCCl,,CO,,test
US05037849,CC(C)(N)C(=O)NCCO[N+](=O)[O-].CC(C)N=C=O>>CC(C)NC(=O)NC(C)(C)C(=O)NCCO[N+](=O)[O-],,CCOC(C)=O,,,,test
US05340831,NC(=O)C(c1ccccc1)(c1ccccc1)C1CCNC1.NC(=O)c1ccc(CCBr)cc1>>NC(=O)c1ccc(CCN2CCC(C(C(N)=O)(c3ccccc3)c3ccccc3)C2)cc1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US06350761B1,BrCc1ccccc1.N#Cc1ccc(O)c([N+](=O)[O-])c1>>N#Cc1ccc(OCc2ccccc2)c([N+](=O)[O-])c1,,CC#N,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20110152240A1,Nc1cc(NC2CC2)n2ncc(C=O)c2n1.O=C(Cl)c1ccccc1F>>O=Cc1cnn2c(NC3CC3)cc(NC(=O)c3ccccc3F)nc12,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US06300363B1,CCOC(=O)n1c(C(=O)c2cccc(Cl)c2)c(N)c2cc([N+](=O)[O-])ccc21>>Nc1c(C(=O)c2cccc(Cl)c2)[nH]c2ccc([N+](=O)[O-])cc12,,CCOC(C)=O,,,,test
US20100273764A1,Cc1nc(-c2cc(Cc3ccc(S(C)(=O)=O)cc3)cnc2F)c2ncn(C3CCCCO3)c2n1.Nc1cccc2c1cnn2C1CCCCO1>>Cc1nc(-c2cc(Cc3ccc(S(C)(=O)=O)cc3)cnc2Nc2cccc3c2cnn3C2CCCCO2)c2ncn(C3CCCCO3)c2n1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20050143579A1,BrC1CCCC1.O=C(O)Cc1cccc(Cl)c1>>O=C(O)C(c1cccc(Cl)c1)C1CCCC1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20050187266A1,Cc1oc(-c2ccccc2)nc1CCOc1ccc(CI)cn1.N#CC1CCCO1>>Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC2(C#N)CCCO2)cn1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20020103253A1,CCOC(=O)CO/C(=C\C#N)C(C)(C)C>>CCOC(=O)c1oc(C(C)(C)C)cc1N,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US07772230B2,COc1ccc(O)cc1.O=C(O)CCCl>>COc1ccc(OCCC(=O)O)cc1,,O,,Cl,[K+].[OH-],test
US03936504,CCc1cccc2c1C(=O)CC2=O.O=[N+]([O-])O>>CCc1cccc2c1C(=O)C([N+](=O)[O-])C2=O,,CCOCC,,,,test
US05132310,Brc1csc2ccccc12.C#CC1(C)CCc2c(C)c(O)c(C)c(C)c2O1>>Cc1c(C)c2c(c(C)c1O)CCC(C)(C#Cc1csc3ccccc13)O2,,CC#N,,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100056510A1,COC(=O)c1cc(-c2cc(SCCNC(=O)OC(C)(C)C)nc(N)n2)c(C)cc1C>>COC(=O)c1cc(-c2cc(SCCN)nc(N)n2)c(C)cc1C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070282003A1,CCOC(=O)CCC(=O)c1ccc(SCc2c(C)cccc2C)cc1>>Cc1cccc(C)c1CSc1ccc(C(=O)CCC(=O)O)cc1,,CCO,,Cl,[Na+].[OH-],test
US20090004185A1,Cc1ccc2c(Cl)nc(Cl)nc2c1.NCc1ccc(NC(=O)C2CCN(Cc3ccccc3)CC2)cc1>>Cc1ccc2c(NCc3ccc(NC(=O)C4CCN(Cc5ccccc5)CC4)cc3)nc(Cl)nc2c1,,ClCCl,,CCN(CC)CC,,test
US20060257987A1,CCOCC.CCc1cccc(C(C)c2ccccc2)c1>>CCc1ccc(O)c(C(C)c2ccccc2)c1,,ClCCl,,,,test
US20100121048A1,CC(=O)O.CC(=O)O[BH-](OC(C)=O)OC(C)=O.ClCCCl.O=C(c1ncn(CC2CCCCN2)c1-c1ccccc1)N1CCN(Cc2ccccc2)C[C@H]1Cc1ccccc1>>Cc1ccc(C(C)CCN2CCCCC2Cn2cnc(C(=O)N3CCN(Cc4ccccc4)C[C@H]3Cc3ccccc3)c2-c2ccccc2)o1,,ClCCCl,,[Na+].[OH-],,test
US20140303143A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1cccc2cnc(N)cc12>>COC(=O)c1cccc2cnc(NC(=O)OC(C)(C)C)cc12,CN(C)c1ccncc1,ClCCl,,,,test
US20130345438A1,C[N+](=O)[O-].O=C1C(=O)N(Cc2ccccc2Br)c2ccccc21>>O=C1N(Cc2ccccc2Br)c2ccccc2C1(O)C[N+](=O)[O-],,O,,,,test
US05241076,CCCCCCCC(CCC)C(=O)[O-]>>CCCCCCCCCCC,,Cl,,O=C([O-])[O-].[K+].[K+],,test
US20100130739A1,Cc1nc(OCC(=O)N(C)C2CCN(Cc3ccccc3)CC2)nc(C)c1N.O=S(=O)(O)c1ccccc1>>Cc1nc(OCC(=O)N(C)C2CCN(Cc3ccccc3)CC2)nc(C)c1N.O=S(=O)(O)c1ccccc1,,CO,,O,,test
US20150018343A1,Cc1nc2c3c(nn2c(C)c1F)CN(C(=O)OC(C)(C)C)C3.Cl>>Cc1nc2c3c(nn2c(C)c1F)CNC3.Cl,,ClCCl,,,,test
US20060003998A1,CC(C)Oc1ccccc1CCl.O=C(c1ccccc1)C1CN(Cc2ccccc2)CCO1>>CC(C)Oc1ccccc1CC(O)(c1ccccc1)C1CN(Cc2ccccc2)CCO1,,C1CCOC1,,II,[Mg],test
US20060270690A1,CC(=O)c1cccc(N(C)S(=O)(=O)c2ccccc2)c1.COC(OC)N(C)C>>CN(C)C=CC(=O)c1cccc(N(C)S(=O)(=O)c2ccccc2)c1,,CCOC(C)=O,CO,,,test
US20150165063A1,COc1cc2c(cc1OCCCCCC(=O)N1C[C@@H](CCl)c3c1cc(OC(=O)N1CCN(C)CC1)c1ccccc31)N(C(=O)OCc1ccc(NC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@@H](NC(=O)OCC3c4ccccc4-c4ccccc43)C(C)C)cc1)[C@@H](O)C1CCCN1C2=O>>COc1cc2c(cc1OCCCCCC(=O)N1C[C@@H](CCl)c3c1cc(OC(=O)N1CCN(C)CC1)c1ccccc31)N(C(=O)OCc1ccc(NC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@@H](N)C(C)C)cc1)[C@@H](O)C1CCCN1C2=O,,CC(=O)N(C)C,,C1CCNCC1,,test
US20090239854A1,CN1CCC(=O)CC1.Fc1ccc(CCBr)cc1.NNc1ccccc1Cl>>CN1CCc2c(c3cccc(Cl)c3n2CCc2ccc(F)cc2)C1,,CCN(CC)CC,,Cl,,test
US20150080451A1,Clc1cccc(CBr)c1.O=S(=O)(/C=C/c1cccc(Cl)c1)Nc1cccc(Cl)c1>>O=S(=O)(/C=C/c1cccc(Cl)c1)N(Cc1cccc(Cl)c1)c1cccc(Cl)c1,,C1CCOC1,,O,[H-].[Na+],test
US20100297054A1,BrCCOC1CCCCO1.Cc1c(C(=O)Nc2cccc(O)c2)nnn1Cc1ccc(Cl)c(Cl)c1>>Cc1c(C(=O)Nc2cccc(OCCO)c2)nnn1Cc1ccc(Cl)c(Cl)c1,CN(C)C=O,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040019098A1,CC1OC(=O)c2ccccc21.O=C1Cc2ccccc2N1>>CC1O/C(=C2/C(=O)Nc3ccccc32)c2ccccc21,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US06166006,CCN1CCCCC1.Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CCl)cc2)CC3)cc1>>CC[N+]1(Cc2ccc(NC(=O)C3=Cc4cc(-c5ccc(C)cc5)ccc4CC3)cc2)CCCCC1.[Cl-],,CN(C)C=O,,CCOC(C)=O,,test
US20020107251A1,Nc1cccc(-n2c(=O)c(Cc3cccnc3)nc3cccnc32)c1.O=C(Cl)c1cc(Cl)cc(Cl)c1>>O=C(Nc1cccc(-n2c(=O)c(Cc3cccnc3)nc3cccnc32)c1)c1cc(Cl)cc(Cl)c1,,C1COCCO1,CCOC(C)=O,CCN(CC)CC,O=C([O-])O.[Na+],test
US20030130340A1,COc1ccc(-c2ccc3c(-c4cccnc4)csc3c2)cc1OC>>Oc1ccc(-c2ccc3c(-c4cccnc4)csc3c2)cc1O,,Br,,[Na+].[OH-],,test
US04772703,Cn1c(COc2cccc([N+](=O)[O-])c2)nc2ccccc21>>Cn1c(COc2cccc(N)c2)nc2ccccc21,[Fe],Cl,,,,test
US20030203909A1,CC(C)(C)CO.N#Cc1cc([N+](=O)[O-])ccc1Cl>>CC(C)(C)COc1ccc([N+](=O)[O-])cc1C#N,,O,,CN(C)C=O,[H-].[Na+],test
US20020099069A1,CCCCCCCCCCCI.CN1CC[C@H]2CCc3ccncc3[C@H]21>>CCCCCCCCCCC[n+]1ccc2c(c1)[C@@H]1[C@H](CC2)CCN1C.[I-],,CC(=O)O,,,,test
US20090286812A1,Cc1ncccc1Oc1ncnc2c1cnn2C1CCNCC1.O=C(Cl)OC1CCCCC1>>Cc1ncccc1Oc1ncnc2c1cnn2C1CCN(C(=O)OC2CCCCC2)CC1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20110028447A1,CC(C)(C)OC(=O)N[C@H](c1nnc(C(N)=O)o1)C(C)(C)C.Cl>>CC(C)(C)[C@H](N)c1nnc(C(N)=O)o1.Cl,,C1COCCO1,,,,test
US20100099673A1,C=O.CC(=O)C1=CCCCC1.CNC>>CN(C)CCC(=O)C1=CCCCC1,,CCO,,Cl,Cl,test
US07015218B1,CC(C)(C)COc1ccc(N)cc1C#N.Cc1nn(C)cc1C(=O)O>>Cc1nn(C)cc1C(=O)Nc1ccc(OCC(C)(C)C)c(C#N)c1,,CN(C)C=O,O,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20100113774A1,CCOC(=O)Cc1ccc(NC(=O)c2ccccc2N)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCOC(=O)Cc1ccc(-n2c(=O)[nH]c3ccccc3c2=O)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04954519,Cl.NCCCOc1cc2ccccc2c(=O)o1.O=C1CCC(=O)N1Cl>>Cl.NCCCOc1oc(=O)c2ccccc2c1Cl,,CN(C)C=O,,,,test
US20030176489A1,Brc1ccc(I)cc1.C#CCO>>OCC#Cc1ccc(Br)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCN(CC)CC,,,,test
US20050203081A1,CCOC(=O)COc1c(C(=O)OC)sc2cc(C)ncc12>>Cc1cc2sc(C(=O)O)c(OCC(=O)O)c2cn1,,C1CCOC1,O,[Li+].[OH-],,test
US20060025459A1,CCI.COC(=O)c1cc(N)c(N)c([N+](=O)[O-])c1>>CCNc1cc(C(=O)OC)cc([N+](=O)[O-])c1N,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04735959,CCCC(c1ccccc1N1CCCCC1)C(C(N)=O)c1ccc(C(=O)NNS(=O)(=O)c2ccc(C)cc2)cc1>>CCCC(c1ccccc1N1CCCCC1)C(C(N)=O)c1ccc(C=O)cc1,,OCCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20110021537A1,CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)OCc3ccccc3)n(-c3cccc(F)c3)n2)CC1>>CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)O)n(-c3cccc(F)c3)n2)CC1,,CCOC(C)=O,,,,test
US20100249139A1,Cc1cc(C(O)(C(C)c2ccc(Br)cc2Cl)C(F)(F)F)ccn1.O=C(O)c1ccc(B(O)O)cc1>>Cc1cc(C(O)(C(C)c2ccc(-c3ccc(C(=O)O)cc3)cc2Cl)C(F)(F)F)ccn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050075376A1,Brc1nc(-c2ccc(OCc3ccccc3)cc2)n(C2CCCCC2)c1Br>>Brc1cn(C2CCCCC2)c(-c2ccc(OCc3ccccc3)cc2)n1,,C1CCOC1,,[Li]CCCC,,test
US20080146569A1,COC(=O)c1ccc(-c2cccc(C#N)c2)nc1>>N#Cc1cccc(-c2ccc(C(=O)O)cn2)c1,,C1CCOC1,,[Li+].[OH-],,test
US20080194549A1,COCCCOc1cc(C(=O)OC)ccc1C#C[Si](C)(C)C>>C#Cc1ccc(C(=O)O)cc1OCCCOC,,CO,,[K+].[OH-],,test
US20070155721A1,CCOC(=O)c1cc2c(Oc3ccc(F)cc3N)cccc2[nH]1>>CCOC(=O)c1cc2c(Oc3ccc(F)cc3)cccc2[nH]1,,CCOCC,CN(C)C=O,CC(C)(C)ON=O,,test
US20150368252A1,COC(=O)C1(COCc2ccccc2)CCCN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCCC1(COCc1ccccc1)C(=O)O,,CO,,[Na+].[OH-],,test
US20110262359A1,CCOC(=O)CN(C)C(=O)[C@H](CN(C)S(=O)(=O)c1ccccc1[N+](=O)[O-])NC(=O)OC(C)(C)C>>CCOC(=O)CN(C)C(=O)[C@@H](N)CN(C)S(=O)(=O)c1ccccc1[N+](=O)[O-],,C1COCCO1,ClCCl,Cl,,test
US20050159599A1,Nc1ccc(SC(F)(F)F)cc1F.O=C=NC(=O)c1c(F)cccc1F>>O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(SC(F)(F)F)cc1F,,CCOCC,,,,test
US05508293,CC(=O)Cl.N#CNC(=NCCO[N+](=O)[O-])c1cncc(N)c1>>CC(=O)Nc1cncc(C(=NCCO[N+](=O)[O-])NC#N)c1,,c1ccncc1,,O=C([O-])O.[Na+],,test
US20040235854A1,Nc1ccc(C(F)(F)F)cc1.O=C(Cl)c1ccc(Cl)cc1Cl>>O=C(Nc1ccc(C(F)(F)F)cc1)c1ccc(Cl)cc1Cl,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20040077707A1,CC(=O)OCC(c1ccc(Cl)cc1Cl)S(=O)(=O)c1ccccc1>>C=C(c1ccc(Cl)cc1Cl)S(=O)(=O)c1ccccc1,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20130210831A1,CN[C@@H]1CCN(c2ncnc3c2ccn3COCC[Si](C)(C)C)C1.CS(=O)(=O)c1ccc(F)cc1>>CN(c1ccc(S(C)(=O)=O)cc1)[C@@H]1CCN(c2ncnc3c2ccn3COCC[Si](C)(C)C)C1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05948819,CC(=O)OC(C)=O.CNC(=O)C(O)c1ccccc1COc1cc(C)ccc1C>>CNC(=O)C(OC(C)=O)c1ccccc1COc1cc(C)ccc1C,,c1ccncc1,,,,test
US05101041,NCCN(CCN)Cc1ccc([N+](=O)[O-])cc1>>NCCN(CCN)Cc1ccc(N)cc1,[Pd],CCO,,,,test
US03997666,COc1ccc(N2CCNCC2)cc1.c1ccc2c(OCC3CO3)cccc2c1>>COc1ccc(N2CCN(CC(O)COc3cccc4ccccc34)CC2)cc1,,CCO,,,,test
US20110112135A1,COc1cccc(-c2c(Cl)nc3c(C(F)(F)F)cccn23)c1>>Oc1cccc(-c2c(Cl)nc3c(C(F)(F)F)cccn23)c1,,ClCCl,,CO,O,test
US20060217387A1,ClI.FC(F)c1cc(-c2cccc(C(F)(F)F)c2)nc2ccnn12>>FC(F)c1cc(-c2cccc(C(F)(F)F)c2)nc2c(I)cnn12,,CC(=O)O,O,CC(=O)[O-].[Na+],,test
US06255276B1,CC(=CCCCCCCC(=O)O)CCCCCO>>CC1=CCCCCCCC(=O)OCCCCC1,,OCC(O)CO,,[K+].[OH-],,test
US20150175594A1,COCCc1noc(-c2c(N)sc3c2CCOC3)n1.O=C1OC(=O)C2=C1CCCC2>>COCCc1noc(-c2c(NC(=O)C3=C(C(=O)O)CCCC3)sc3c2CCOC3)n1,,CCOCC,ClCCl,,,test
US20060009451A1,C#CCCO.Oc1ccc(-c2c3c(nc4ccnn24)CCC3)cc1I>>OCCc1cc2cc(-c3c4c(nc5ccnn35)CCC4)ccc2o1,[Cu]I,CN(C)C=O,,CCN(CC)CC,,test
US04310538,O=C(CC(=O)OCc1ccccc1)CC1CC(=O)N1.[N-]=[N+]=NS(=O)(=O)c1ccc(C(=O)O)cc1>>[N-]=[N+]=C(C(=O)CC1CC(=O)N1)C(=O)OCc1ccccc1,,CC#N,CCOC(C)=O,CCN(CC)CC,,test
US04927835,C=O.CC(C)(C)c1cc(C(=O)c2ccccc2)ccc1O.CNC>>CN(C)Cc1cc(C(=O)c2ccccc2)cc(C(C)(C)C)c1O,,CCO,,Cl,[Na+].[OH-],test
US20100179148A1,CCOC(=O)Nc1cccc(Cn2nc(-c3ccc(C#N)cc3)ccc2=O)c1.[NH3+]O>>CCOC(=O)Nc1cccc(Cn2nc(-c3ccc(C(=N)NO)cc3)ccc2=O)c1,,CCO,,CCN(CC)CC,,test
US05952351,COC(=O)[C@@H]1CNCC[C@H]1n1c(=O)[nH]c2ccccc21.O=C1c2cc(Cl)ccc2S(=O)(=O)N1CCCCBr>>COC(=O)[C@@H]1CN(CCCCN2C(=O)c3cc(Cl)ccc3S2(=O)=O)CC[C@H]1n1c(=O)[nH]c2ccccc21,,ClCCl,,,,test
US20100216746A1,CC[Zn]CC.N#Cc1cc(Br)cc(Oc2c(Cl)ccc(CN)c2F)c1>>CCc1cc(C#N)cc(Oc2c(Cl)ccc(CN)c2F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,,,test
US20100150831A1,CC(C)(C)OC(=O)N1CCCNCC1.COc1c(C)cc2cccnc2c1Br>>Cc1cc2cccnc2c(N2CCCN(C(=O)OC(C)(C)C)CC2)c1O,,CCOC(C)=O,,,,test
US06265575B1,BrBr.COc1ccc(-c2cc3ccccc3s2)cc1>>COc1ccc(-c2sc3ccccc3c2Br)cc1,,ClC(Cl)Cl,,,,test
US20090156610A1,COC(=O)c1ccc(O)cc1.O=Cc1cc(Cl)ccc1F>>COC(=O)c1ccc(Oc2ccc(Cl)cc2C=O)cc1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20080176857A1,CCc1cc2c(N3CCNCC3)nc(SCC(=O)OC)nc2s1.O=C(Cl)C=Cc1ccccc1>>CCc1cc2c(N3CCN(C(=O)/C=C/c4ccccc4)CC3)nc(SCC(=O)OC)nc2s1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20120289549A1,COC(=O)[C@H]1C[C@H](O)CN1.O=C=Nc1ccc(OCC(F)(F)F)cc1>>COC(=O)[C@H]1C[C@H](O)CN1C(=O)Nc1ccc(OCC(F)(F)F)cc1,,C1CCOC1,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20100152207A1,CN(C(=O)c1ccc(Cl)c(-c2nc3ccccc3cc2C#N)c1)c1ccccc1CCCC(=O)OC(C)(C)C>>CN(C(=O)c1ccc(Cl)c(-c2nc3ccccc3cc2C#N)c1)c1ccccc1CCCC(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20020183314A1,C=CCN1c2ccc3nc(OC(C)C)cc(C(F)(F)F)c3c2OC[C@H]1CC>>CCCN1c2ccc3nc(OC(C)C)cc(C(F)(F)F)c3c2OC[C@H]1CC,[Pd],CCOC(C)=O,,CCN(CC)CC,,test
US20140155381A1,CC(C)OCC#N.Cc1ccc([Mg]Br)c(C)c1>>Cc1ccc(C(N)COC(C)C)c(C)c1,,C1CCOC1,O,CO,[BH4-].[Na+],test
US06403610B1,ClCCBr.Sc1ccc(Cl)s1>>ClCCSc1ccc(Cl)s1,,CCOC(C)=O,,[Na+].[OH-],,test
US20130116245A1,CC[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1ccc(Nc2cc(Br)cn(C)c2=O)nc1>>CC[C@H]1CNCCN1c1ccc(Nc2cc(Br)cn(C)c2=O)nc1,,ClCCl,,C1COCCO1,Cl,test
US20090275542A1,C[C@]12CC[C@H]3[C@@H](C[C@@H]4O[C@@]45C[C@@H](O)CC[C@]35C)[C@@H]1CCC2=O>>C[C@]12CC[C@H]3[C@@H](CC[C@@]4(O)C[C@@H](O)CC[C@]34C)[C@@H]1CC[C@@H]2O,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080113978A1,CCC(CC)c1cc(C)nn2cc(C)nc12.Cc1noc(-c2ccccc2)c1Br>>CCC(CC)c1cc(C)nn2c(-c3c(C)noc3-c3ccccc3)c(C)nc12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04533676,NC(=O)c1cc(F)ccc1Cl.O=C=Nc1ccc(OC(F)(F)F)cc1>>O=C(NC(=O)c1cc(F)ccc1Cl)Nc1ccc(OC(F)(F)F)cc1,,Cc1ccccc1,,,,test
US20110201593A1,N#CCCN1CCC(Nc2c(N)cnc3c2ccn3S(=O)(=O)c2ccccc2)CC1.O=C(O)CCNC(=O)OCC1c2ccccc2-c2ccccc21>>N#CCCN1CCC(Nc2c(NC(=O)CCNC(=O)OCC3c4ccccc4-c4ccccc43)cnc3c2ccn3S(=O)(=O)c2ccccc2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120010401A1,COC(=O)[C@@H](CN(c1ccccc1NC(=O)OC(C)(C)C)C1CCCCC1)NC(=O)C(F)(F)F>>O=C1Nc2ccccc2N(C2CCCCC2)C[C@H]1NC(=O)C(F)(F)F,,Cc1ccccc1,,Cl,,test
US05527763,CCOC(=O)c1c(O)csc1CSC.COc1cc(OC)nc(S(C)(=O)=O)n1>>CCOC(=O)c1c(Oc2nc(OC)cc(OC)n2)csc1CSC,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100280071A1,CCCO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C4CC4)ccc3N)CC2)CC1.ClCCl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCCO[C@@H]1CC[C@@H](N2CCC(n3c(=O)[nH]c4ccc(C5CC5)cc43)CC2)CC1.Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110166164A1,CC(C)(C)OC(=O)NCCc1ccc(Oc2cc(C#N)ccn2)cc1>>N#Cc1ccnc(Oc2ccc(CCN)cc2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(O)C(C)C)CC2)c2ccnn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(O)C(C)C)CC2)c2ccnn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20090069250A1,CC(=O)NCC(C(=O)Nc1ccccc1)c1ccc(C(=O)OC(C)(C)C)cc1>>CC(=O)NCC(C(=O)Nc1ccccc1)c1ccc(C(=O)O)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130137679A1,COc1ccc(NC(=O)OC(C)(C)C)c(N)c1>>COc1ccc2[nH]c(=O)[nH]c2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080188484A1,CC(C)N1CCC(O)CC1.CCOC(=O)c1cc2cc(O)c(C)cc2[nH]1>>CCOC(=O)c1cc2cc(OC3CCN(C(C)C)CC3)c(C)cc2[nH]1,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100267722A1,Cc1cc(N2C[C@H](S(=O)(=O)c3ccc(F)cc3Cl)C[C@H]2C(=O)NC2(C#N)CC2)n(CCc2ccccc2)n1.FC1(F)CNC1>>Cc1cc(N2C[C@H](S(=O)(=O)c3ccc(N4CC(F)(F)C4)cc3Cl)C[C@H]2C(=O)NC2(C#N)CC2)n(CCc2ccccc2)n1,,CC#N,,Cl,,test
US20150342185A1,Cc1cc(Br)ccc1C1OC12C(=O)C(C)(C)OC2(C)C>>Cc1cc(Br)ccc1C1C(=O)C(C)(C)OC(C)(C)C1=O,,ClCCl,,O=S(=O)(O)O,,test
US20140171438A1,CC(C)(C)OC(=O)NCC#Cc1cc([N+](=O)[O-])ccc1F.Nc1cc(O)cc(C(F)(F)F)c1>>CC(C)(C)OC(=O)NCC#Cc1cc([N+](=O)[O-])ccc1Oc1cc(N)cc(C(F)(F)F)c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20120083475A1,NO.O=Cc1c[nH]c2ccc(Cl)cc12>>NCc1c[nH]c2ccc(Cl)cc12,[Zn],CCO,,Cl,CC(=O)[O-].[Na+],test
US04956379,COC(=O)COc1cccc(CCc2cc(-c3ccccc3)n(-c3ccccc3)n2)c1>>O=C(O)COc1cccc(CCc2cc(-c3ccccc3)n(-c3ccccc3)n2)c1,,CO,,[Na+].[OH-],,test
US20070010542A1,O=C(OCC1(CF)OCCCO1)c1ccccc1>>OCC1(CF)OCCCO1,,CO,,[Na+].[OH-],[Cl-].[NH4+],test
US20070249642A1,FC(F)(F)c1ccc([C@@]23CNC[C@@H]2C3)cc1.O=CCCn1cc(I)c(=O)n(C(=O)c2ccccc2)c1=O>>O=C(c1ccccc1)n1c(=O)c(I)cn(CCCN2C[C@@H]3C[C@]3(c3ccc(C(F)(F)F)cc3)C2)c1=O,,ClCCl,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140066369A1,C[Si](C)(C)C(F)(F)F.O=C1COC1>>OC1(C(F)(F)F)COC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120202998A1,C=C1C(CO)C(O)CC1n1cnc2c(=O)[nH]c(N)nc21.O>>C=C1C(CO)C(O)CC1n1cnc2c(=O)[nH]c(N)nc21.O,,O,,CN(C)C=O,,test
US04680301,CC1CCN(c2cc3nc(C(C)(C)C)sc3cc2[N+](=O)[O-])CC1>>CC1CCN(c2cc3nc(C(C)(C)C)sc3cc2N)CC1,[Ni],CO,,,,test
US06248739B1,CCOCC(O)OCC.O=C(NCc1ccc(Cl)cc1)c1cnc2ccc(CN3CCOCC3)cc2c1O>>CCOCCOCCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCOCC3)ccc21,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04304781,BrCc1ccccc1.CN1CCCCC1=S>>C[N+]1=C(SCc2ccccc2)CCCC1.[Br-],,CC(C)=O,,,,test
US20140349993A1,FC(F)(F)c1ccccc1-c1ccc(Cl)nn1.NN>>NNc1ccc(-c2ccccc2C(F)(F)F)nn1,,CCO,,O,,test
US04220647,COc1ccc(CCNC(=O)CNc2ccc(C)cc2)cc1OC.O=C(Cl)OCc1ccccc1>>COc1ccc(CCNC(=O)CN(C(=O)OCc2ccccc2)c2ccc(C)cc2)cc1OC,,ClC(Cl)Cl,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130053366A1,CC1(c2ccncc2)CO1.Cc1ccc2[nH]c3c(c2c1)CCN(C)C3>>Cc1ccc2c(c1)c1c(n2CC(C)(O)c2ccncc2)CN(C)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20080249150A1,CCC(CC)C(N=[N+]=[N-])c1ccnn1OCc1ccccc1>>CCC(CC)C(N)c1ccnn1OCc1ccccc1,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040102467A1,C=CCBr.COc1ccc2[nH]ccc2c1>>C=CCn1ccc2cc(OC)ccc21,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20110263582A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@H](NCCC(=O)c1ccc(F)cc1)C(C)(C)C>>C[C@H](N(CCC(=O)c1ccc(F)cc1)C(=O)OC(C)(C)C)C(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20090036450A1,Cc1nc(CO)oc1C(C)(C)O[SiH2]C(C)(C)C.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1nc(COC(c2ccccc2)(c2ccccc2)c2ccccc2)oc1C(C)(C)O[SiH2]C(C)(C)C,CN(C)c1ccncc1,ClC(Cl)Cl,,CCN(CC)CC,O,test
US20020183307A1,CCCCC1(CCCC)CN(c2ccc(OC)cc2)c2cc(F)ccc2S(=O)(=O)C1.CNC>>CCCCC1(CCCC)CN(c2ccc(OC)cc2)c2cc(N(C)C)ccc2S(=O)(=O)C1,,C1CCOC1,,,,test
US20030176454A1,CN(C)C=C1CCc2ccccc2C1=O.Cc1ncc(-c2cccc(NC(=N)N)c2)n1C>>Cc1ncc(-c2cccc(Nc3ncc4c(n3)-c3ccccc3CC4)c2)n1C,,CCO,,Cl,Cl,test
US20040132727A1,COc1cc2nccc(Oc3ccc(N)c(C)c3C)c2cc1OC.Cc1ccc(C)c(SCCO)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)OCCSc4cc(C)ccc4C)c(C)c3C)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20140128600A1,CCOC(=O)c1cn(CC)c2ncc(NC3Cc4ccccc4C3)cc2c1=O>>CCn1cc(C(=O)O)c(=O)c2cc(NC3Cc4ccccc4C3)cnc21,,CCO,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[Na+].[OH-],test
US20150005258A1,CN(CCCC(=O)O)C(=O)OC(C)(C)C.NCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]>>CN(CCCC(=O)NCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)OC(C)(C)C.[Br-],,CN(C)C=O,ClCCl,O=C(n1ccnc1)n1ccnc1,,test
US05045223,NS(=O)(=O)c1ccc(Cl)cc1.O=Cc1ccc(Cl)cc1>>O=S(=O)(N=Cc1ccc(Cl)cc1)c1ccc(Cl)cc1,,Cc1ccccc1,,,,test
US20050113356A1,C[C@@](O)(C(=O)O)C1CCCCC1.NCCN1CCc2cc(F)ccc21>>O=C(NCCN1CCc2cc(F)ccc21)[C@@H](O)CC1CCCCC1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060235037A1,Cc1cc(C2=CCN(C(=O)OC(C)(C)C)CC2)cc([N+](=O)[O-])c1N>>Cc1cc(N)c([N+](=O)[O-])cc1C1=CCNCC1,,ClCCCl,,O=C(O)C(F)(F)F,,test
US20120094964A1,COC(=O)c1ccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)cc1>>O=C(O)c1ccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)cc1,,C1CCOC1,,[Na+].[OH-],,test
US20130059835A1,CCOc1c(C(C)O)cc(Cl)c(C#N)c1N1CCCC1.O=S(Cl)Cl>>CCOc1c(C(C)Cl)cc(Cl)c(C#N)c1N1CCCC1,,CCOC(C)=O,ClCCl,CN(C)C=O,,test
US20050282768A1,NC1(Cl)N=CN=C2C1=NCN2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O.NN>>NNNc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O,,CO,,O,,test
US20120258973A1,CCOC(=O)COc1cc(C)c2c(-c3cc(OC)cc(OC)c3)nn(C)c2n1>>COc1cc(OC)cc(-c2nn(C)c3nc(OCC(=O)O)cc(C)c23)c1,,C1COCCO1,O,[Li+].[OH-],,test
US20010001101A1,CCOC=C(C(=O)OCC)C(=O)OCC.Nc1ccccc1[N+](=O)[O-]>>CCOC(=O)C(=CNc1ccccc1[N+](=O)[O-])C(=O)OCC,,CCO,,,,test
US20050075453A1,CCCCCCCCCN.O=C1OC(=O)c2ccc3c4cccc5cccc(c6ccc1c2c63)c54>>CCCCCCCCCN1C(=O)c2ccc3c4cccc5cccc(c6ccc(c2c36)C1=O)c54,,CN1CCCC1=O,,,,test
US20110152285A1,CCOC(=O)c1[nH]c(C)c(C(=O)OCC)c1-c1ccccc1.CI>>CCOC(=O)c1c(-c2ccccc2)c(C(=O)OCC)n(C)c1C,,C1CCOC1,,[H-].[Na+],,test
US05770624,CCCO[C@@H]1CC[C@@H]([C@H](C(=O)OCc2ccccc2)N(Cc2ccncc2)S(=O)(=O)c2ccc(OC)cc2)CC1.Cl>>CCCO[C@@H]1CC[C@@H]([C@H](C(=O)O)N(Cc2ccncc2)S(=O)(=O)c2ccc(OC)cc2)CC1.Cl,[Pd],CCO,,,,test
US20030008304A1,COC(=O)C1Cc2c(ccc3[nH]ccc23)N1.COc1ccc(C(OCCCN(CCCC(=O)Oc2c(F)c(F)c(F)c(F)c2F)c2ccc(N=Nc3ccc([N+](=O)[O-])cc3Cl)cc2)(c2ccccc2)c2ccc(OC)cc2)cc1>>COC(=O)C1Cc2c(ccc3c2ccn3C(=O)CCCN(CCCOC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)c2ccc(N=Nc3ccc([N+](=O)[O-])cc3Cl)cc2)N1,,CN(C)C=O,,CCN(CC)CC,,test
US20080269191A1,COC(=O)c1cccc(-c2nc3cc(Br)ccc3o2)c1.O=C1CCCN1>>O=C(O)c1cccc(-c2nc3cc(N4CCCC4=O)ccc3o2)c1,[Cu]I,O,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20160229814A1,CC(CC(=O)O)CC(=O)Nc1ccc(C#N)c(Cl)c1.CCn1c(=O)n(CC2COC2)c(=O)c2cc(N)ccc21>>CCn1c(=O)n(CC2COC2)c(=O)c2cc(NC(=O)CC(C)CC(=O)Nc3ccc(C#N)c(Cl)c3)ccc21,,CCOC(C)=O,O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US05266698,C1CCOC1.CC(=O)O.CN(C)C=C1NC(=O)N(c2ccccc2)C1=O>>O=c1c2c[nH]c3c(n-2c(=O)n1-c1ccccc1)CCCC3,,C1CCOC1,CN(C)C=O,CC(C)(C)[O-].[K+],,test
US20070197530A1,CC(=O)O.OC1CC2CCCC(C1)N2Cc1ccccc1>>CC(=O)OC1CC2CCCC(C1)N2,[Pd],,,[H][H],,test
US09273028B2,CN(c1ncnc2c1cnn2COCC[Si](C)(C)C)[C@H]1CCCNC1>>CN(c1ncnc2[nH]ncc12)[C@H]1CCCNC1,,CCO,,Cl,,test
US20140018344A1,C[C@H](N)c1nc2ccn(C)c2cc1-c1ccnn1C.Nc1nc(Cl)c2cn[nH]c2n1>>C[C@H](Nc1nc(N)nc2[nH]ncc12)c1nc2ccn(C)c2cc1-c1ccnn1C,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20090298823A1,CC(C)(C)OC(=O)NCC1CCNCC1.Clc1ncc(Br)c(Cl)n1>>CC(C)(C)OC(=O)NCC1CCN(c2nc(Cl)ncc2Br)CC1,,CC#N,CCOC(C)=O,CCN(C(C)C)C(C)C,O,test
US20090062366A1,COC(=O)C(C)(C)COC(=O)N1C[C@H](c2ccccc2)[C@@H](CN(C(=O)OC(C)(C)C)[C@H](C)c2cccc3ccccc23)C1>>COC(=O)C(C)(C)COC(=O)N1C[C@H](c2ccccc2)[C@@H](CN[C@H](C)c2cccc3ccccc23)C1,,Cc1ccccc1,,C1COCCO1,Cl,test
US20160244409A1,CC(C)CN1C=CC(C)(C)CC1.O=C(Cl)c1ccc(Br)cc1>>CC(C)CN1C=C(C(=O)c2ccc(Br)cc2)C(C)(C)CC1,,ClCCl,,CCN(CC)CC,,test
US03932430,O=C1CCCc2ccccc21.O=Cc1ccncc1>>O=C1C(=Cc2ccncc2)CCc2ccccc21,,CC(=O)O,,C1CCNCC1,,test
US20090105474A1,CC(C)(C)OC(=O)c1ccc(N)cc1Nc1ccc(F)cc1.O=C(Cl)c1csc2ccccc12>>CC(C)(C)OC(=O)c1ccc(NC(=O)c2csc3ccccc23)cc1Nc1ccc(F)cc1,,CCN(CC)CC,ClCCl,O=C([O-])O.[Na+],,test
US20030105099A1,CCN(CC)S(F)(F)F.COC(=O)[C@H](CCCc1ccccc1)[C@H](O)C(=O)N1CCOCC1>>COC(=O)[C@H](CCCc1ccccc1)C(F)C(=O)N1CCOCC1,,ClCCl,,,,test
US20050143422A1,COC(=O)[C@@H](NS(=O)(=O)c1ccc(-c2ccc(N)cc2)cc1)C(C)C.Cc1c(C(=O)O)oc2cccc(-c3cccc([N+](=O)[O-])c3)c12>>COC(=O)[C@@H](NS(=O)(=O)c1ccc(-c2ccc(NC(=O)c3oc4cccc(-c5cccc([N+](=O)[O-])c5)c4c3C)cc2)cc1)C(C)C,,c1ccncc1,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20090227584A1,COCCC(=O)Cl.Nc1cccc2nc(N[C@@H]3CCc4ccccc43)ccc12>>COCCC(=O)Nc1cccc2nc(N[C@@H]3CCc4ccccc43)ccc12,CN(C)c1ccncc1,c1ccncc1,,,,test
US04859692,COc1cc(C(=O)O)ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12.NC(=O)C1C=CC=C[N+]1(c1ccccc1)c1ccccc1>>COc1cc(C(=O)OC(=O)N(c2ccccc2)c2ccccc2)ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12,,CCO,,Cl,[Na+].[OH-],test
US05618821,Cc1nc(-c2cc(C)c(O)c(C)c2)no1.OCCCc1cnc2ccccc2c1>>Cc1nc(-c2cc(C)c(OCCCc3cnc4ccccc4c3)c(C)c2)no1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070225267A1,CC(=O)Oc1cccc(CC[N+](=O)[O-])c1.CC(C)(C)OC(=O)N1[C@@H](C=O)COC1(C)C>>CC(=O)Oc1cccc(C[C@@H]([C@H](O)[C@H]2COC(C)(C)N2C(=O)OC(C)(C)C)[N+](=O)[O-])c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20060173014A1,COC[C@H](C)N.O=S(=O)(Cl)c1ccc(Br)cc1>>COC[C@H](C)NS(=O)(=O)c1ccc(Br)cc1,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20100240658A1,CN(CC(=O)OC(C)(C)C)Cc1cccc(C#N)c1.NO>>CN(CC(=O)OC(C)(C)C)Cc1cccc(C(N)=NO)c1,,CCO,,,,test
US07091227B2,CCNC(=O)Nc1nc2c(s1)C(Sc1ccccc1)(Sc1ccccc1)CCC2>>CCNC(=O)Nc1nc2c(s1)C(Sc1ccccc1)=CCC2,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20040162352A1,COc1ccc2c(c1)CCC(NC(C)=O)C2>>CC(=O)NC1CCc2cc(O)ccc2C1,,ClCCl,,BrB(Br)Br,,test
US20130338081A1,CN(C)C=O.CN1CCOCC1.C[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C.ClCCCl.O=C(N[C@@H]1CN[C@H](C(=O)N[C@@H]2CCCc3ccccc32)C1)OCC1c2ccccc2-c2ccccc21.On1nnc2cccnc21>>C[C@@H](C(=O)N[C@H](C(=O)N1C[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21)C(C)(C)C)N(C)C(=O)OC(C)(C)C,,CN(C)C=O,O,,,test
US07777042B2,CC(=O)c1ccc(C[C@H](NC(=O)[C@@H]2CCCCN2S(=O)(=O)c2cccc(C(F)(F)F)c2)C(=O)OCc2ccccc2)cc1>>CC(O)c1ccc(C[C@H](NC(=O)[C@@H]2CCCCN2S(=O)(=O)c2cccc(C(F)(F)F)c2)C(=O)O)cc1,[Pd],CO,,[H][H],,test
US08815877B2,CN(Cc1nc2ccn(COCC[Si](C)(C)C)c2cc1F)C(=O)OC(C)(C)C>>CNCc1nc2ccn(COCC[Si](C)(C)C)c2cc1F,,ClCCl,O=C(O)C(F)(F)F,,,test
US05576322,NC(=O)c1ccc2ncnc(O)c2c1.O=S(Cl)Cl>>N#Cc1ccc2ncnc(Cl)c2c1,,O=P(Cl)(Cl)Cl,,,,test
US20080188452A1,Nc1ccc2c(c1)C(=O)CCCC2.O=C(Cl)OCc1ccccc1>>O=C(Nc1ccc2c(c1)C(=O)CCCC2)OCc1ccccc1,,CO,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20070099927A1,NC(=O)c1cccc(-c2cccc(Cl)c2)c1>>NCc1cccc(-c2cccc(Cl)c2)c1,,C1CCOC1,,B,,test
US20140018319A1,CC(C)(C)OC(=O)Nc1cccc(C(N)=O)n1>>CC(C)(C)OC(=O)Nc1cccc(C#N)n1,,ClCCl,,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US20140045872A1,COc1ccc(Cn2cc(/C=C\[N+](=O)[O-])c3ccccc32)cc1>>COc1ccc(Cn2cc(CCN)c3ccccc32)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060014945A1,N=C(NO)c1ccc(CN(C2CCCCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)cc1.O=C(O)COCc1ccccc1>>O=C1NCCCCC1N(Cc1ccc(-c2noc(COCc3ccccc3)n2)cc1)S(=O)(=O)c1ccc(Cl)cc1,,CN(C)C=O,,O,O=C(n1ccnc1)n1ccnc1,test
US20150018352A1,CC(C)(C)OC(=O)N1CCc2c(cccc2B2OC(C)(C)C(C)(C)O2)C1.CN1CCNCC1.Fc1cc(C(F)(F)F)ccc1Br>>CN1CCN(c2cc(C(F)(F)F)ccc2-c2cccc3c2CCN(C(=O)OC(C)(C)C)C3)CC1,,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US09266853B2,CC#CCOc1ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)N(C)C)cc1>>CC#CCOc1ccc(C[C@H](N)C(=O)N(C)C)cc1,,CCOC(C)=O,Cl,,,test
US04208420,CN=C1CCCc2scnc21>>CNC1CCCc2scnc21,O=[Pt],CCO,,[H][H],,test
US20140235583A1,CCOC(=O)CNC(=O)c1ncc(C(=O)NC(c2ccc(F)cc2)c2ccc(F)cc2)c(O)n1>>O=C(O)CNC(=O)c1ncc(C(=O)NC(c2ccc(F)cc2)c2ccc(F)cc2)c(O)n1,,[K+],[OH-],,,test
US20150119380A1,CCOC(=O)Cc1cn2cc(C)ccc2n1.O=Cc1ccc(CO)cc1O>>Cc1ccc2nc(-c3cc4ccc(CO)cc4oc3=O)cn2c1,,CCO,,C1CCNCC1,CC(=O)O,test
US20080242654A1,CC(C)Cn1cc(C(C)(C)C)sc1=N.O=C(Cl)c1cc(Cl)ccc1F>>CC(C)Cn1cc(C(C)(C)C)s/c1=N\C(=O)c1cc(Cl)ccc1F,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20050075378A1,Cc1oc(-c2ccc(O)cc2)nc1CCOc1ccc(CCC(=O)OC(C)(C)C)c(CNC(=O)OC(C)C)c1.OC1CCOCC1>>Cc1oc(-c2ccc(OC3CCOCC3)cc2)nc1CCOc1ccc(CCC(=O)OC(C)(C)C)c(CNC(=O)OC(C)C)c1,,Cc1ccccc1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140221341A1,CC(C)(C)OC(=O)N[C@@H]1CCC[C@H]1C(=O)NN.O=C(O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H]1CCC[C@H]1C(=O)NNC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20040077859A1,CCOc1nc(N)nc(N)c1N.O=CC=O>>CCOc1nc(N)nc2nccnc12,,CCO,,,,test
US05716971,C=C(C)OC.C[Si](C)(C)Oc1cccnc1C#N.Oc1ccc(Br)cc1Br>>O=C(c1cc(Br)ccc1O)c1ncccc1O,,CCOCC,,[Li]CCCC,,test
US20070078120A1,BrCc1ccccc1.COc1cccc(C2(C#N)CCNCC2)c1>>COc1cccc(C2(C#N)CCN(Cc3ccccc3)CC2)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120178744A1,CCOC(=O)CC1CCC(c2cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n3ncc(-c4ccc(-c5ccccc5)nc4)c3n2)CC1.O=C1CCC(=O)N1Br>>CCOC(=O)CC1CCC(c2nc3c(-c4ccc(-c5ccccc5)nc4)cnn3c(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)c2Br)CC1,,CC#N,,,,test
US20150023913A1,COC(=O)C(C)(C)C1CCCO1>>CC(C)(C(=O)O)C1CCCO1,,C1CCOC1,,O,[Li+].[OH-],test
US06936602B1,CC(C)(C)OC(=O)CCCN(c1ccc(Br)cc1C=O)C1CC1>>O=C(O)C1=Cc2cc(Br)ccc2N(C2CC2)CC1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US05461050,Cn1cccc1CCCS(=O)(=O)[O-].c1c[nH]cn1>>Cn1cccc1CCn1ccnc1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US04898977,C=CC(O)CC1CCCCC1.CC(C)CC(=O)Cl>>C=CC(CC1CCCCC1)OC(=O)CC(C)C,CN(C)c1ccncc1,CCOCC,ClCCl,CCN(CC)CC,,test
US20140057899A1,C=C[C@@H](CCn1c(Br)c(-c2cnc3ccccc3c2)c2c(N)ncnc21)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@H]1CCc2c(-c3cnc4ccccc4c3)c3c(N)ncnc3n2CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,B1C2CCCC1CCC2,[Na+].[OH-],test
US20070203155A1,CC(N)=S.O=C(CBr)c1ccc(OC(F)(F)F)cc1>>Cc1nc(-c2ccc(OC(F)(F)F)cc2)cs1,,CCO,,,,test
US20070078131A1,Cc1cccc(C(=O)c2c(C#N)sc3c2ccc(=O)n3-c2ccccc2)c1.[OH-]>>Cc1cccc(C(=O)c2c(C(N)=O)sc3c2ccc(=O)n3-c2ccccc2)c1,,CCO,,Cl,,test
US04305937,NOCC(F)(F)F.O=CNc1nc(C(=O)C(=O)O)cs1>>O=CNc1nc(C(=NOCC(F)(F)F)C(=O)O)cs1,,CO,O,Cl,[Na+].[OH-],test
US20120283297A1,CC(C)Oc1ncc(C(=O)O)cc1C#N.CCOC(=O)CCn1ncc2cc(C(=N)NO)ccc21>>CCOC(=O)CCn1ncc2cc(-c3noc(-c4cnc(OC(C)C)c(C#N)c4)n3)ccc21,,CCOC(C)=O,CN(C)C=O,ClCCCl,,test
US20040067913A1,CNCCS(=O)(=O)O.COc1ccc(C2C(CCC(O)c3ccc(F)cc3)C(=O)N2c2ccc(OCCCCF)cc2)cc1>>COc1ccc(C2C(CCC(O)c3ccc(F)cc3)C(=O)N2c2ccc(OCCCCN(C)CCS(=O)(=O)O)cc2)cc1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20080021056A1,CC(CC(=O)OC(C)(C)C)Nc1ccccc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>CC(CC(=O)OC(C)(C)C)N(c1ccccc1)S(=O)(=O)c1ccc(Cl)cc1,,c1ccncc1,,,,test
US05559143,Nc1ccc(C(F)(F)F)cc1.O=C(Cl)CCCCCBr>>CC(CCCNC(=O)CCCCCBr)C(F)(F)F,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US05808062,Cc1ccc(S(=O)(=S)OCc2cccc(Oc3ccccc3)c2)cc1.O=c1oc(-c2ccccc2)cc(O)c1SSc1c(O)cc(-c2ccccc2)oc1=O>>O=c1oc(-c2ccccc2)cc(O)c1SCc1cccc(Oc2ccccc2)c1,,CCO,,[Na+].[OH-],,test
US20040235891A1,COc1ccc2c(c1)C(CCc1ccc(F)cc1)=NCC2>>COc1ccc2c(c1)C(CCc1ccc(F)cc1)NCC2,,CO,,[BH4-].[Na+],,test
US06384028B1,O=C(O)C(F)(F)F.O=C(O)[C@H](CNC(=O)[C@@H]1CCCN(C(=O)/C=C/C2CCNCC2)C1)NC(=O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C(O)[C@H](CNC(=O)[C@@H]1CCCN(C(=O)CCC2CCNCC2)C1)NC(=O)C(F)(F)F,[Pd],O,,,,test
US20090012093A1,COC(=O)CCc1ccc(OCc2ccc(C=O)cc2)cc1.Nc1nc(-c2ccccc2)cs1>>COC(=O)CCc1ccc(OCc2ccc(CNc3nc(-c4ccccc4)cs3)cc2)cc1,,ClCCCl,,CC(=O)O,O=C([O-])O.[Na+],test
US20120034270A1,COc1cc(C#Cc2cccc(C#CC3(NC(=O)OC(C)(C)C)COC(C)(C)OC3)c2)cc(OC)c1OC>>COc1cc(CCc2cccc(CCC3(NC(=O)OC(C)(C)C)COC(C)(C)OC3)c2)cc(OC)c1OC,[Pd],CCO,,,,test
US20110245303A1,CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CBr)c1.Sc1ccccc1>>CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CSc2ccccc2)c1,,C1COCCO1,,[H-].[Na+],,test
US08410284B2,CC(C)(C)[Si](C)(C)Cl.Cc1ccc(O)cc1I>>Cc1ccc(O[Si](C)(C)C(C)(C)C)cc1I,,CCOCC,CN(C)C=O,c1c[nH]cn1,,test
US06153605,BrC(Br)(Br)Br.C[C@H](C=O)[C@H]1CC[C@H]2[C@@H](O[Si](C)(C)C(C)(C)C)CCC[C@]12C>>C[C@H](C=C(Br)Br)[C@H]1CC[C@H]2[C@@H](O[Si](C)(C)C(C)(C)C)CCC[C@]12C,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060252812A1,O=C(CN1C(=O)C2(COc3cc(F)c(F)cc32)c2c(Br)cccc21)Nc1ccccc1F.OB(O)c1cncnc1>>O=C(CN1C(=O)C2(COc3cc(F)c(F)cc32)c2c(-c3cncnc3)cccc21)Nc1ccccc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US20120142667A1,COC(=O)CBr.Cc1ccc([N+](=O)[O-])cc1O>>COC(=O)COc1cccc([N+](=O)[O-])c1C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120277208A1,CC(C)Oc1cc(Oc2cnc(C(=O)NNC(=O)OC(C)(C)C)cn2)cc(C(=O)Nc2ccn(C)n2)c1>>CC(C)Oc1cc(Oc2cnc(C(=O)NN)cn2)cc(C(=O)Nc2ccn(C)n2)c1,,CCOC(C)=O,,Cl,,test
US20110269740A1,CO.O=C(c1cc(Cl)c[nH]1)C(Cl)(Cl)Cl>>COC(=O)c1cc(Cl)c[nH]1,,ClCCl,,C[O-].[Na+],,test
US20030045670A1,O=[N+]([O-])c1cc(C(F)(F)F)cc([N+](=O)[O-])c1P(=O)(c1ccccc1)c1ccccc1>>Nc1cc(C(F)(F)F)cc(N)c1P(=O)(c1ccccc1)c1ccccc1,,Cl,,C1COCCO1,,test
US20060122399A1,CCc1cc(CCC2(C3CCCC3)CC(=O)CC(=O)O2)ccc1CC#N.Cc1cc(C)n2nc(C=O)nc2n1>>CCc1cc(CCC2(C3CCCC3)CC(O)=C(Cc3nc4nc(C)cc(C)n4n3)C(=O)O2)ccc1CC#N,,CO,,,,test
US04156079,COc1ccc(OCCCN2CCOCC2)c(CNCCc2ccccc2)c1.O=C(Cl)c1ccc(Cl)cc1>>COc1ccc(OCCCN2CCOCC2)c(CN(CCc2ccccc2)C(=O)c2ccc(Cl)cc2)c1.Cl,,ClC(Cl)Cl,,,,test
US20050038068A1,C=CCOc1ccc(-c2c(C)sc(N)c2C(=O)OCC)cc1.N#CCC(=O)O>>C=CCOc1ccc(-c2c(C)sc(NC(=O)CC#N)c2C(=O)OCC)cc1,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20130324551A1,COCN(c1cccc(C(=O)CBr)c1F)S(=O)(=O)c1cc(F)ccc1F.NC(N)=S>>COCN(c1cccc(-c2csc(N)n2)c1F)S(=O)(=O)c1cc(F)ccc1F,,CCO,,,,test
US20150141455A1,ON=C1CC[C@H](c2ccccc2)C1>>N[C@H]1CCC(c2ccccc2)C1,[Zn],CC(=O)O,,,,test
US20110178060A1,COC(=O)C1(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1>>O=C(O)C1(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1,,CO,,Cl,[Na+].[OH-],test
US20100022550A1,CC(C)C(=O)NC1CCC(=O)CC1.NNc1ccc2c(c1)OC(F)(F)O2>>CC(C)C(=O)NC1CCc2[nH]c3cc4c(cc3c2C1)OC(F)(F)O4,,O,,Cl,Cl,test
US20070015744A1,COC(OC)N(C)C.Cc1cccc([N+](=O)[O-])c1[N+](=O)[O-]>>COC(Cc1cccc([N+](=O)[O-])c1[N+](=O)[O-])OC,,CN(C)C=O,CO,C[Si](C)(C)Cl,,test
US20060160794A1,CCOC(=O)CC(C)=O.[N-]=[N+]=NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CCOC(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1C,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150038488A1,CCNc1c(OCc2ccccc2)cc(Br)cc1[N+](=O)[O-].O=CO>>CCn1cnc2cc(Br)cc(OCc3ccccc3)c21,[Fe],O=CO,,CCO,,test
US20020099215A1,CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CN1CCCC(C(=O)NC(CCCc2ccccc2)CCCc2ccccc2)C1>>NC(Cc1ccccc1)C(O)CN1CCCC(C(=O)NC(CCCc2ccccc2)CCCc2ccccc2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04332808,CN1CCCC(O)(c2cccc3c2ccn3C)C1>>CN1CCC=C(c2cccc3c2ccn3C)C1,,Cl,,[Na+].[OH-],,test
US20040116698A1,Cn1c(=O)c(Oc2ccccc2F)cc2cnc(S(C)(=O)=O)nc21.N>>Cn1c(=O)c(Oc2ccccc2F)cc2cnc(N)nc21,,CN1CCCC1=O,,,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Nc1ccc(N2CCCC2=O)cc1>>COc1ccc2nc(Nc3ccc(N4CCCC4=O)cc3)c3[nH]ncc3c2c1,C1COCCO1,CO,,Cl,,test
US20080281075A1,CC(C)C1=N[C@H](c2ccccc2)COC1=O>>CC(C)[C@@H]1N[C@H](c2ccccc2)COC1=O,O=[Pt]=O,ClCCl,,,,test
US05486611,CC(C)(C)[Si](C)(C)Cl.OCCCC1c2c(Br)cccc2CCC1O>>CC(C)(C)[Si](C)(C)OCCCC1c2c(Br)cccc2CCC1O,,CN(C)C=O,O,c1c[nH]cn1,,test
US20070010670A1,COC(=O)c1ccc(C(=O)Cl)cc1.c1ccc2c(c1)NCCO2>>COC(=O)c1ccc(C(=O)N2CCOc3ccccc32)cc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20080255197A1,Cc1cnc(N(CCCNO)C2CCCc3cccnc32)c(C)c1.N#C[O-]>>Cc1cnc(N(CCCN(O)C(N)=O)C2CCCc3cccnc32)c(C)c1,,O,,[Na+].[OH-],,test
US20050118317A1,CNC(=O)[C@@]1(Cc2c[nH]c3ccccc23)C[C@@H](NC(=O)OCc2ccccc2)C(=O)O1.CO>>CNC(=O)[C@@](O)(Cc1c[nH]c2ccccc12)C[C@@H](N)C(=O)O,[Pd],,,[H][H],,test
US20140256740A1,COC(=O)C(C)(C)c1ccc(OC)cc1>>CC(C)(C(=O)O)c1ccc(O)cc1,,ClCCl,,BrB(Br)Br,O,test
US04705807,N#CC(=Cc1ccccc1Cl)C(=O)O>>N#C/C=C\c1ccccc1Cl,[Cu],,,O=C=O,,test
US20140343000A1,NCCN1CCS(=O)(=O)CC1.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=[N+]([O-])c1ccccc1S(=O)(=O)NCCN1CCS(=O)(=O)CC1,,ClCCl,,CCN(CC)CC,,test
US20120122838A1,C1COCCN1.CCOC(=O)CC(=O)Cl>>CCOC(=O)CC(=O)N1CCOCC1,,ClCCl,,CCN(CC)CC,O,test
US20060189827A1,Cc1ccc(OC(CC(=O)N(C(C)C)C(C)C)c2ccccc2)cc1>>Cc1ccc(O)c(C(CC(=O)N(C(C)C)C(C)C)c2ccccc2)c1,,Cc1ccccc1,,[Na+].[OH-],,test
US20130338196A1,OC(c1ncc(-c2ccccn2)o1)C1CCc2cc(Oc3ccccc3)ccc2C1>>O=C(c1ncc(-c2ccccn2)o1)C1CCc2cc(Oc3ccccc3)ccc2C1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20110062541A1,CCCCCCCC(=O)Cl.c1cc2sccc2s1>>CCCCCCCC(=O)c1cc2sccc2s1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20150094328A1,Fc1ccc(CBr)cc1.O=C(N[C@H]1CCOC[C@@H]1O)c1c[nH]c2c(Cl)ccnc12>>O=C(N[C@H]1CCOC[C@@H]1O)c1cn(Cc2ccc(F)cc2)c2c(Cl)ccnc12,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04849419,CC(=O)Oc1ccc(C(=O)Cl)cc1.Fc1c(F)c(F)c(S)c(F)c1F>>CC(=O)Oc1ccc(C(=O)Sc2c(F)c(F)c(F)c(F)c2F)cc1,,ClCCl,,c1ccncc1,,test
US06232290B1,COC(=O)c1ccc(-c2nnc(-c3ccc(N4CCCCC4)nc3)s2)cc1.Cl>>Cl.O=C(O)c1ccc(-c2nnc(-c3ccc(N4CCCCC4)nc3)s2)cc1,,CCO,O,C1CCOC1,[Na+].[OH-],test
US20100234593A1,O=C(c1ccc(-c2nc3c(I)c(F)cnc3[nH]2)cc1)N1CCOCC1>>Fc1cnc2[nH]c(-c3ccc(CN4CCOCC4)cc3)nc2c1I,,C1CCOC1,,B,,test
US20110070317A1,O=C(OO)c1cccc(Cl)c1.O=C([O-])N1CC=CCC1>>O=C(OCc1ccccc1)N1CCC2OC2C1,,ClCCl,,CCOCC,,test
US20120077847A1,CC(C)(C)OC(=O)NNC(=S)c1ccc(OCc2ccccc2)cc1>>NNC(=S)c1ccc(OCc2ccccc2)cc1,,C1COCCO1,Cl,,,test
US20140343092A1,COC(=O)c1c(O)c2ccn(Cc3ccccc3)c2c(=O)n1C.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1c(OS(=O)(=O)C(F)(F)F)c2ccn(Cc3ccccc3)c2c(=O)n1C,,ClCCl,,CCN(CC)CC,,test
US20040068121A1,CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CCC(=O)CC(=O)CC(=O)OC(C)(C)C>>CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(=O)OC(C)(C)C,,O=CO,,CCN(CC)CC,Cc1ccccc1,test
US20080293706A1,Cc1ncc(Br)cc1N.O=S(=O)(Cl)C1CC1>>Cc1ncc(Br)cc1NS(=O)(=O)C1CC1,,c1ccncc1,,,,test
US20040106606A1,CC(C)C1(CCc2csc(CO)c2)CC(O)=CC(=O)O1.Cc1ccc(S(=O)(=O)Sc2cc(C)c(CO)cc2C(C)(C)C)cc1>>Cc1cc(SC2=C(O)CC(CCc3csc(CO)c3)(C(C)C)OC2=O)c(C(C)(C)C)cc1CO,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US09283555B2,CC(C)(C)c1ccccc1N.Cc1ccc(C#N)cc1>>Cc1ccc(C(=N)Nc2ccccc2C(C)(C)C)cc1,,O,,[Li]CCCC,,test
US20150133669A1,CC(=O)C1CCCC1.CCOC(=O)C(=O)OCC.N#CCC(N)=O>>O=C(O)c1cc(O)nc(C2CCCC2)c1,,O,,C1CCOC1,,test
US20100179126A1,C#Cc1cnc(C)c([N+](=O)[O-])c1.CNC>>Cc1ncc(CCN(C)C)cc1[N+](=O)[O-],,CCO,,Cl,[BH3-]C#N.[Na+],test
US04562189,BrCCCCOc1ccccc1.O=CN1CCNCC1>>c1ccc(OCCCCN2CCNCC2)cc1,,CC(C)O,,,,test
US20080234494A1,CCOC(=O)Cc1c(Cl)ccc2cc(C=O)ccc12.CNC>>CCOC(=O)Cc1c(Cl)ccc2cc(CN(C)C)ccc12,,C1CCOC1,CO,CC(=O)O,[BH3-]C#N.[Na+],test
US04382143,CCCCCCCCCCCCCCCCN(C(=O)C(F)(F)F)c1csc(C(=O)Cl)c1.CCOC(=O)C(O)C(O)C(=O)OCC>>CCCCCCCCCCCCCCCCNc1csc(C(=O)OC(C(=O)OCC)C(O)C(=O)OCC)c1,,CCOCC,,CCN(CC)CC,,test
US20120270875A1,CN(C)C(=O)CCl.Cc1nc(NCCCc2cccc3[nH]ncc23)nc(C)c1C(=O)N[C@@H](CNC(=O)c1cccs1)C(=O)O>>Cc1nc(NCCCc2cccc3[nH]ncc23)nc(C)c1C(=O)N[C@@H](CNC(=O)c1cccs1)C(=O)OCC(=O)N(C)C,,CCOC(C)=O,CN(C)C=O,[I-].[K+],O=C([O-])O.[Na+],test
US20070197478A1,CCOC(=O)N(Cc1ccc(C)nc1)c1cc(C(F)(F)F)nc(N)c1[N+](=O)[O-]>>Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)cn1,[Pd],CC(=O)O,,,,test
US05705516,Cc1ccc(S(=O)(=O)OCCC=C(F)F)cc1.Cc1nsc(=S)[nH]1>>Cc1nsc(SCCC=C(F)F)n1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030212111A1,CCNc1ccc(N)cc1[N+](=O)[O-].O=C(Cl)CBr>>CC(=O)Nc1ccccc1,,ClC(Cl)Cl,,,,test
US20110112065A1,BrCc1ccccc1.CCCNCC1OCc2ccc(S(C)(=O)=O)cc2O1>>CCCN(Cc1ccccc1)CC1OCc2ccc(S(C)(=O)=O)cc2O1,,CCOC(C)=O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20050261245A1,CC(C)(C)[Si](C)(C)Cl.OCc1cccc(O)c1>>CC(C)(C)[Si](C)(C)OCc1cccc(O)c1,,CN(C)C=O,,c1c[nH]cn1,,test
US04978753,C#CC(=O)OCC.NC1=Nc2ccc(Cl)cc2C(c2ccccc2Br)=NC1>>O=c1ccn2c(n1)CN=C(c1ccccc1Br)c1cc(Cl)ccc1-2,,CCO,,,,test
US20070072897A1,Nc1c(F)cccc1Nc1ccccc1.O=C(c1ncc[nH]1)c1ncc[nH]1>>O=c1[nH]c2c(F)cccc2n1-c1ccccc1,CN(C)c1ccncc1,C1CCOC1,CCOC(C)=O,,,test
US20120184579A1,CCc1nc2c(F)ccc(OCC(=O)OC)c2c(OC(F)F)c1Cc1ccc(B(O)O)cc1.c1n[nH]cc1C1CC1>>CCc1nc2c(F)ccc(OCC(=O)OC)c2c(OC(F)F)c1Cc1ccc(-n2cc(C3CC3)cn2)cc1,,O,,c1ccncc1,,test
US20110118275A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Nc1ncc(Br)nc1-c1nc2cnccc2o1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(-c3cnc(N)c(-c4nc5cnccc5o4)n3)cc2)CC1,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20150315197A1,CC(C)(C)OC(=O)N1CC=C(OS(=O)(=O)C(F)(F)F)CC1.OB(O)c1cc(F)ccc1Cl>>CC(C)(C)OC(=O)N1CC=C(c2cc(F)ccc2Cl)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US06111101,N#C[Cu]C#N.O=C(Cl)c1cccc(Cl)c1Cl>>N#CC(=O)c1cccc(Cl)c1Cl,,Cc1ccccc1,,CC#N,,test
US20160108047A1,CC(C)OC(=O)Cl.Cc1cc(N2C(=O)c3nc(C4=CCNCC4)n(C(C)C)c3C2c2ccc(Cl)cc2)cn2c(C)nnc12>>Cc1cc(N2C(=O)c3nc(C4=CCN(C(=O)OC(C)C)CC4)n(C(C)C)c3C2c2ccc(Cl)cc2)cn2c(C)nnc12,,ClCCl,c1ccncc1,O=C([O-])O.[Na+],,test
US20110319378A1,C=CCI.CC(C)N1S[C@H](C)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1>>C=CC[C@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(C(C)C)S1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20040254185A1,Nc1cc2ccccc2cn1.O=C(Cl)c1cccnc1Cl>>O=C(Nc1cc2ccccc2cn1)c1cccnc1Cl,,C1CCOC1,,,,test
US20070287712A1,CC(C)(C)OC(=O)N1CCNCC1.N#CC(C#N)=C(Cl)c1ccccc1>>CC(C)(C)OC(=O)N1CCN(C(=C(C#N)C#N)c2ccccc2)CC1,,CCO,,CCN(CC)CC,,test
US20090247530A1,CN(C)C1(c2cccc(F)c2)CCC(C)(CN)CC1.O=C(Cl)C=Cc1ccccc1>>CN(C)C1(c2cccc(F)c2)CCC(C)(CNC(=O)/C=C/c2ccccc2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US06214872B1,CCI.O=C(O)CCN(C1(C(=O)OCc2ccccc2)CCCC1)S(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1>>CCOC(=O)CCN(C1(C(=O)OCc2ccccc2)CCCC1)S(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150307491A1,Brc1ccc(C2CCNCC2)cc1.CC(=O)Cl>>CC(=O)N1CCC(c2ccc(Br)cc2)CC1,,C1CCOC1,,Cl,,test
US08735584B2,COC(=O)c1ccc2c(c1)c(=O)[nH]c1nccc(Nc3ccc(NC(=O)c4ccccc4)cc3)c12>>O=C(Nc1ccc(Nc2ccnc3[nH]c(=O)c4cc(CO)ccc4c23)cc1)c1ccccc1,,C1CCOC1,,[BH4-].[Li+],,test
US20060199817A1,Cc1ccc(C(N)=O)cc1B1OC(C)(C)C(C)(C)O1.O=C1CN(c2nncc3cc(Br)ccc23)CCN1>>Cc1ccc(C(N)=O)cc1-c1ccc2c(N3CCNC(=O)C3)nncc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O=C([O-])[O-].[K+].[K+],,test
US05401756,O=c1c2cc(Br)ccc2nnn1Cc1cccnc1.Oc1ccc(Cl)cc1>>O=c1c2cc(Oc3ccc(Cl)cc3)ccc2nnn1Cc1cccnc1,,c1ccncc1,,O=C([O-])[O-].[K+].[K+],,test
US03974161,CCOC(=O)C(=O)OCC.NC(=O)c1cc2cc(F)ccc2nc1N>>CCOC(=O)c1nc2nc3ccc(F)cc3cc2c(=O)[nH]1,,CCCCCC,,,,test
US20130102577A1,C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@@H](O)CC[C@@]43C)[C@@H]1CCC2=O.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)O[C@H]2CC[C@@]3(C)[C@@H](CC[C@H]4[C@@H]5CCC(=O)[C@@]5(C)CC[C@@H]43)C2)cc1,,c1ccncc1,,,,test
US20060160788A1,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCC(OS(C)(=O)=O)CC1.N#Cc1ccc(O)cc1>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCC(Oc2ccc(C#N)cc2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US05716993,O=C(NCc1ccc2c(c1)OCO2)c1cc(Cl)ccc1[N+](=O)[O-]>>Nc1ccc(Cl)cc1C(=O)NCc1ccc2c(c1)OCO2,[Fe],CCO,,CC(=O)O,O,test
US20100168418A1,COC(=O)Nc1cccc2c1ccc(=O)n2CCN1CCC(N(Cc2ccc3c(c2)OCCO3)C(=O)OC(C)(C)C)CC1.Cl>>COC(=O)Nc1cccc2c1ccc(=O)n2CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1.Cl,,C1COCCO1,,,,test
US20090018103A1,CS(=O)(=O)Cl.C[C@@H](O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C>>C[C@@H](OS(C)(=O)=O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,O,test
US20090227600A1,COc1cc(C(=O)N2[C@@H](c3nccs3)[C@@H](c3cnccn3)C[C@@]2(CC(C)C)C(=O)OC(C)(C)C)ccc1C(C)(C)C>>COc1cc(C(=O)N2[C@@H](c3nccs3)[C@@H](c3cnccn3)C[C@@]2(CC(C)C)C(=O)O)ccc1C(C)(C)C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100120760A1,C1COCCN1.CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c3c(c12)CC(COS(C)(=O)=O)O3>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c3c(c12)CC(CN1CCOCC1)O3,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160159820A1,CC1CN(Cc2ccc(C(=O)N[C@@H]3[C@H]4Oc5ccc(Oc6ccnc7c6CCC(=O)N7)cc5[C@@H]34)cc2C(F)(F)F)CC(C)N1C(=O)OC(C)(C)C>>CC1CN(Cc2ccc(C(=O)N[C@@H]3[C@H]4Oc5ccc(Oc6ccnc7c6CCC(=O)N7)cc5[C@@H]34)cc2C(F)(F)F)CC(C)N1,,CCOC(C)=O,,Cl,,test
US06645991B1,CCOC(=O)C(C#N)=Cc1ccccc1.ClCc1ccc(OCc2ccccc2)cc1>>CCOC(=O)C(C#N)C(Cc1ccc(OCc2ccccc2)cc1)c1ccccc1,,Cc1ccccc1,,C1CCOC1,,test
US20040192767A1,CCOC(=O)c1ccoc1C(C)C>>CC(C)c1occc1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20020123498A1,O=C(CC(=O)N1CCNCC1)NC(CCCc1ccccc1)CCCc1ccccc1.c1cc(OC[C@H]2CO2)c2cccnc2c1>>O=C(CC(=O)N1CCN(C[C@@H](O)COc2cccc3ncccc23)CC1)NC(CCCc1ccccc1)CCCc1ccccc1,,CCO,,,,test
US20110009391A1,CC(C)(C)OC(=O)N1CCN(c2ccc(N3CCNCC3)cn2)c2ccccc21.O=S(=O)(Cl)C1CC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(N3CCN(S(=O)(=O)C4CC4)CC3)cn2)c2ccccc21,,CCN(CC)CC,,ClCCl,,test
US20140323518A1,Cc1noc(C)c1-c1c(C#C[Si](C)(C)C)cc(C(F)(F)F)cc1-c1ccc(O)cc1>>C#Cc1cc(C(F)(F)F)cc(-c2ccc(O)cc2)c1-c1c(C)noc1C,,C1CCOC1,,,,test
US20150005289A1,CCOC(=O)C(=O)CBr.Cc1cnc(N)cn1>>CCOC(=O)c1cn2cc(C)ncc2n1,,CCO,COCCOC,,,test
US20020033192A1,CN(C)C=O.Ic1ccc(-c2cc[nH]c2)cc1>>O=Cc1[nH]ccc1-c1ccc(I)cc1,,ClCCl,,O=P(Cl)(Cl)Cl,,test
US20120157432A1,CC(C)(C)OC(=O)N1CCC(n2cccn2)CC1>>c1cnn(C2CCNCC2)c1,,C1COCCO1,Cl,,,test
US20110257100A1,O=C(n1ccnc1)n1ccnc1.OCCCNCc1ccc(Br)nc1>>O=C1OCCCN1Cc1ccc(Br)nc1,,ClCCl,,,,test
US20080242643A1,CC(C)(C)[Si](C)(C)OC/C(=C(\COC(=O)OCC(CO[N+](=O)[O-])O[N+](=O)[O-])c1ccc(S(C)(=O)=O)cc1)c1ccccc1>>CS(=O)(=O)c1ccc(/C(COC(=O)OCC(CO[N+](=O)[O-])O[N+](=O)[O-])=C(/CO)c2ccccc2)cc1,,CC#N,Cc1ccccc1,,,test
US05102667,O=C(O)Cc1c(F)cccc1F.O=C1CCC(c2ccccc2)(c2ccccc2)C2CNCC12>>O=C1CCC(c2ccccc2)(c2ccccc2)C2CN(C(=O)Cc3c(F)cccc3F)CC12,,ClCCl,,CCN(CC)CC,Cl,test
US05037825,COC(=O)c1ccc(/C=C(\C)c2ccc3c(c2)N(C)CCN3C)cc1>>C/C(=C\c1ccc(C(=O)O)cc1)c1ccc2c(c1)N(C)CCN2C,,CCO,O,[K+].[OH-],,test
US20160251321A1,CCI.Cc1cc(F)c(-n2ccc(=O)[nH]c2=O)cc1SCC(F)(F)F>>CCn1c(=O)ccn(-c2cc(SCC(F)(F)F)c(C)cc2F)c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20160137589A1,CCN(C)C.CCOC(=O)CCCBr>>CCOC(=O)CCC[N+](C)(C)CC.[Br-],,ClCCl,,,,test
US20130261077A1,CNC(=O)c1cccc(Cc2cccc([C@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H]3OC(C)=O)c2)c1>>CNC(=O)c1cccc(Cc2cccc([C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)c2)c1,,CO,,CO[Na],,test
US05554621,COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc(N)c1.O=C(Cl)CCCCl>>COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc(NC(=O)CCCCl)c1,,C1CCOC1,,,,test
US20130157851A1,Cc1cc([N+](=O)[O-])c(C)cc1Sc1cccc(OC(F)F)c1>>Cc1cc(Sc2cccc(OC(F)F)c2)c(C)cc1N,[Fe],CCO,O,CC(=O)O,,test
US20150376181A1,COc1ccc(CN2CCn3c(ccc(Nc4ccncn4)c3=O)C2=O)cc1>>O=C1NCCn2c1ccc(Nc1ccncn1)c2=O,,O=C(O)C(F)(F)F,,,,test
US04006109,C#CC(C)=CC(C)(C)O.CC(C)C=O>>CC(C#CC(O)C(C)C)=CC(C)(C)O,,c1ccccc1,,[Cl-].[NH4+],,test
US04180522,CC(CCl)CN(C)C.Nc1ccc(Br)c(Br)c1>>CC(CNc1ccc(Br)c(Br)c1)CN(C)C,,Cc1ccccc1,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20090124666A1,Cc1ncoc1-c1ccc(C(F)(F)F)cc1.ClC(Cl)(Cl)C(Cl)(Cl)Cl>>Cc1nc(Cl)oc1-c1ccc(C(F)(F)F)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US06077841,CCCc1nn(C)c(C(N)=O)c1NC(=O)c1sccc1OCC>>CCCc1nn(C)c2c(=O)[nH]c(-c3sccc3OCC)nc12,,CCO,O,[Na+].[OH-],,test
US20080146625A1,CCOC(=O)C(=O)c1ccc(SC)cc1.O=S([O-])OO>>CCOC(=O)C(=O)c1ccc(S(C)(=O)=O)cc1,,O,,CO,,test
US20040171777A1,C=COC(C)=O.S=C(S)c1ccccc1>>CC(=O)OC(C)SC(=S)c1ccccc1,,ClC(Cl)(Cl)Cl,,,,test
US20090275592A1,C=CCOC(=O)n1nnc2ccccc21.Nc1cc(-c2ccc3cnccc3c2)on1>>C=CCOC(=O)Nc1cc(-c2ccc3cnccc3c2)on1,,CN(C)C=O,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20150368228A1,NC12CC3CC(CC(C3)C1)C2.O=S(=O)(Cl)c1ccc(Br)cn1>>O=S(=O)(NC12CC3CC(CC(C3)C1)C2)c1ccc(Br)cn1,,c1ccncc1,,,,test
US20140315888A1,CNC1CN(c2nc3ncc(Br)cc3n3cnnc23)C1.O=C(O)/C=C\C(=O)O>>CNC1CN(c2nc3ncc(Br)cc3n3cnnc23)C1.O=C(O)/C=C\C(=O)O,,CCO,,,,test
US20140107097A1,Cn1nncc1C(=O)c1cnnn1C.FC(F)(F)c1nc2ccc(Br)cc2c(C(F)(F)F)c1-c1ccccc1>>Cn1nncc1C(O)(c1ccc2nc(C(F)(F)F)c(-c3ccccc3)c(C(F)(F)F)c2c1)c1cnnn1C,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OCC3(CO[Si](C)(C)C(C)(C)C)CCC3)CC2)c2ncnn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n([C@@H]2CC[C@@H](OCC3(CO)CCC3)CC2)c2ncnn12,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US20140194418A1,COc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1nc(SC)nc(N)c1C(N)=O.O=C(CCl)CCl>>COc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1nc(SC)n2cc(CCl)nc2c1C(N)=O,,COCCOC,,,,test
US06221867B1,CC(=O)C(C)=O.COc1cc[nH]c1/C=C1\C(=O)Nc2ccc(N)c(N)c21>>COc1cc[nH]c1/C=C1\C(=O)Nc2ccc3nc(C)c(C)nc3c21,,CCO,,,,test
US20110112127A1,COC(=O)c1cc(C(=O)OC)[nH]n1.COc1ccc(CCl)cc1>>COC(=O)c1cc(C(=O)OC)n(Cc2ccc(OC)cc2)n1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04625047,C=C(CC)C(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl.CCOC(=O)CC(C)=O>>CCC1CCC(=O)C=C1c1ccc(OCC(=O)O)c(Cl)c1Cl,,CCO,,C[O-].[Na+],,test
US04316839,CN1Cc2c(C=NO)ncn2-c2ccc(F)cc2C1=O>>CN1Cc2c(C#N)ncn2-c2ccc(F)cc2C1=O,,CC(=O)OC(C)=O,,,,test
US04614614,COc1ccc(CN(CS(=O)(=O)C(C)(C)C)C(=O)[C@H]2CO2)cc1>>COc1ccc(CN2C(=O)[C@H](CO)[C@H]2S(=O)(=O)C(C)(C)C)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05116992,CCCCCCCCCCCCCCCCCCNC.OCC1CO1>>CCCCCCCCCCCCCCCCCCN(C)CC(O)CO,,Cc1ccccc1,,,,test
US04008258,CC(C=CCC(C)CCCC(C)C)=CC(=O)O.OCC1CC1>>CC(C=CCC(C)CCCC(C)C)=CC(=O)OCC1CC1,,c1ccccc1,,,,test
US05514680,CC(=O)Nc1c([N+](=O)[O-])cc(F)cc1C(F)(F)F>>Nc1c([N+](=O)[O-])cc(F)cc1C(F)(F)F,,Cl,,,,test
US05521311,CS(=O)(=O)Nc1cc(N)ccc1Oc1ccccc1.O=C(Cl)CCl>>CS(=O)(=O)Nc1cc(NC(=O)CCl)ccc1Oc1ccccc1,,O,,ClCCl,c1ccncc1,test
US20120058988A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(N)cc2)CC1.N#Cc1cc(Br)ccc1F>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(Nc3ccc(Br)cc3C#N)cc2)CC1,,CS(C)=O,ClCCl,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US20050137236A1,NCCOc1ccc(I)cc1>>NCCOc1ccc(I)cc1,,ClC(Cl)Cl,,Cl,O=C([O-])O.[Na+],test
US05134111,CCCc1cccc2c(C=O)cc(OC)c(O)c12.COCCl>>CCCc1cccc2c(C=O)cc(OC)c(OCOC)c12,,CN(C)C=O,,O,[H-].[Na+],test
US20080227839A1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.Fc1ccc(-c2cc[nH]n2)c(F)c1>>Fc1ccc(-c2ccn(C(c3ccccc3)(c3ccccc3)c3ccccc3)n2)c(F)c1,,c1ccncc1,,CN(C)c1ccccn1,,test
US20100168418A1,CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)cnc3ccc(Br)cc32)CC1>>O=c1cnc2ccc(Br)cc2n1CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US04426380,Cc1cc(C(C)C(=O)O)c(O)cc1-n1cccc1>>Cc1cc2c(cc1-n1cccc1)OC(=O)C2C,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US06147088,Cc1cc(C)cc(-c2c(OCC[C@@H]3CCCCN3C(=O)OC(C)(C)C)c3cc(N)c(Cl)cc3[nH]c2=O)c1.NC1CC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>Cc1cc(C)cc(-c2c(OCC[C@@H]3CCCCN3C(=O)OC(C)(C)C)c3cc(NC(=O)NC4CC4)c(Cl)cc3[nH]c2=O)c1,,CCOC(C)=O,,c1ccncc1,,test
US20100009975A1,CC(C)(C)OC(=O)N1CCC(N2CCSc3ccccc32)C1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N1CCC(N2CCSc3cc(Br)ccc32)C1,,CN(C)C=O,O,,,test
US05360811,Cc1ccc(S(=O)(=O)Cl)cc1.O=Cc1c[nH]c2ccc(Br)cc12>>Cc1ccc(S(=O)(=O)n2cc(C=O)c3cc(Br)ccc32)cc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US06777432B1,COC(=O)CCS.O=C(Nc1ccc(F)cc1)c1ccc(Cl)nc1>>COC(=O)CCSc1ccc(C(=O)Nc2ccc(F)cc2)cn1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US05476938,Nc1cc[nH]c(=O)n1.OC[C@@H]1CO1>>Nc1ccn(C[C@H](O)CO)c(=O)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080306153A1,O=C(O)CCCCCCCCCCCCCCCCCCC(=O)O>>OCCCCCCCCCCCCCCCCCCCCO,,O,,C1CCOC1,O=C([O-])O.[Na+],test
US05208228,CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(=O)C(OC)C3)C(C)C(O[Si](C(C)C)(C(C)C)C(C)C)CC1=O)C(C)CC2OC>>CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(=O)C(OC)C3)C(C)C(O)CC1=O)C(C)CC2OC,,CC#N,,,,test
US20030018064A1,CCOC(=O)CCc1csc2cc(OCCc3ccc4c(n3)N(C(=O)OC(C)(C)C)CCC4)ccc12>>CC(C)(C)OC(=O)N1CCCc2ccc(CCOc3ccc4c(CCC(=O)O)csc4c3)nc21,,O,,C1CCOC1,[Na+].[OH-],test
US06380201B1,CN1CC=C(c2c[nH]c3ccc([N+](=O)[O-])cc23)CC1>>O=[N+]([O-])c1ccc2[nH]ccc2c1,[Pd],CCO,Cl,[H][H],,test
US20040102360A1,Clc1cc(C2CCC2)c(Cl)nn1.NNC(=O)c1ccccc1>>Clc1nn2c(-c3ccccc3)nnc2cc1C1CCC1,,Cc1ccc(C)cc1,,CCN(CC)CC,Cl,test
US03970684,CCCCCC(=O)OC.COP(C)(=O)OC>>CCCCCC(=O)CP(=O)(OC)OC,,C1CCOC1,,CC(=O)O,[Li]CCCC,test
US05985872,Cc1c(NC(=O)OC(C)(C)C)ccc2[nH]c(=O)oc(=O)c12>>Cc1c(NC(=O)OC(C)(C)C)ccc(N)c1C(=O)O,,CC(C)=O,,Cl,[Na+].[OH-],test
US20060089370A1,CCN(CC)CC.COC(=O)c1sc2ncnc(Cl)c2c1OC.COc1ccc(C(C)N)cc1>>CCOC(=O)c1sc2ncnc(NC(C)c3ccc(OC)cc3)c2c1OC,,CN(C)C=O,O,,,test
US20050130954A1,C1CNCCN1.CC(C)(C)OC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)O>>CC(C)(C)OC(=O)NC(Cc1ccc(Cl)cc1)C(=O)N1CCNCC1,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20140343029A1,CC(C)I.Nc1ncnc(Cl)c1O>>CC(C)Oc1c(N)ncnc1Cl,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04281000,Cc1cnc2ccnn2c1-c1cccnc1.O=C1CCC(=O)N1Br>>Cc1cnc2c(Br)cnn2c1-c1cccnc1,,ClCCl,,,,test
US20160237095A1,COc1ccc2c(c1)CNC2.Clc1nccc(Nc2ccc(Br)cc2)n1>>COc1ccc2c(c1)CN(c1nccc(Nc3ccc(Br)cc3)n1)C2,,CC#N,,CCN(C(C)C)C(C)C,,test
US05162308,CCOC(=O)/C=C/C(F)(F)F.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>CCOC(=O)c1c[nH]cc1C(F)(F)F,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20070244092A1,COC(=O)C1CCN(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCOCC2)C1>>CC(C)(C)c1nc2cc(S(=O)(=O)N3CCC(C(=O)O)C3)ccc2n1CC1CCOCC1,,O,,CO,[Na+].[OH-],test
US20070021414A1,COc1ccc(C2(O)CCN(CC(O)c3ccc(O)c(Cl)c3)CC2)cn1.Cl>>COc1ccc(C2(O)CCN(CC(O)c3ccc(O)c(Cl)c3)CC2)cn1.Cl,,CCOC(C)=O,CO,,,test
US20110105461A1,CCCNCCC.Cc1ccc(S(=O)(=O)OC[C@H]2COc3c(Cl)cc(S(C)(=O)=O)cc3O2)cc1>>CCCN(CCC)C[C@H]1COc2c(Cl)cc(S(C)(=O)=O)cc2O1,,CC#N,,,,test
US20080188452A1,CCOC(=O)CCCBr.COC(=O)c1ccccc1O>>CCOC(=O)CCCOc1ccccc1C(=O)OC,,CC(C)=O,,[I-].[K+],,test
US20110268698A1,CC#N.COc1ccc2cc(C)[nH]c2c1>>COc1ccc2c(C#N)c(C)[nH]c2c1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20080269210A1,CC(C)(O)c1cc2nc(Cl)nc(N3CCOCC3)c2s1.CI>>COC(C)(C)c1cc2nc(Cl)nc(N3CCOCC3)c2s1,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US04956359,C=CCN.O=C(Cl)N1CC(Oc2cccc(Br)c2)C1>>C=CCNC(=O)N1CC(Oc2cccc(Br)c2)C1,,C1CCOC1,O,,,test
US04443466,Cc1[nH]cnc1CCl.Nc1c(Cl)cccc1Cl>>Cc1[nH]cnc1Cc1cc(Cl)c(N)c(Cl)c1,,Cc1ccccc1C,,Cl,,test
US20100130556A1,O=C(O)C=Cc1cccc(CC(O)c2ccc(-c3ccccc3)o2)c1>>O=C(O)C=Cc1cccc(C=Cc2ccc(-c3ccccc3)o2)c1,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US05268386,COc1cc(OC)c2c(c1)OC1(CCCCC1)CC2=O>>O=C1CC2(CCCCC2)Oc2cc(O)cc(O)c21,,Br,,,,test
US20130231333A1,CCOC(=O)/C=C/c1ccc(/C(=C(/CC)c2ccc(O)cc2)c2ccc3c(cnn3C3CCCCO3)c2)cc1.COCCO>>CCOC(=O)/C=C/c1ccc(/C(=C(/CC)c2ccc(OCCOC)cc2)c2ccc3c(cnn3C3CCCCO3)c2)cc1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20160068496A1,CCCS(=O)(=O)Nc1cccc(-c2cc(OC)c3nc(-c4cccc5c4cnn5C4CCCCO4)nc(N4CCOCC4)c3c2)c1F>>CCCS(=O)(=O)Nc1cccc(-c2cc(OC)c3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3c2)c1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090233924A1,CC(C)c1cc(N)on1.COc1cc2ncnc(Oc3ccc(CC(=O)O)cc3)c2cc1OC>>COc1cc2ncnc(Oc3ccc(CC(=O)Nc4cc(C(C)C)no4)cc3)c2cc1OC,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20100099681A1,CC1(C)C(=O)N(Br)C(=O)N1Br.COC(=O)c1ccccc1Nc1cc(C)nn1-c1ccccc1>>COC(=O)c1ccccc1Nc1c(Br)c(C)nn1-c1ccccc1,,ClCCl,,,,test
US20130096118A1,CCOC(=O)N1CCc2[nH]c3c(Br)ccc(Br)c3c2C1>>Brc1ccc(Br)c2c3c([nH]c12)CCNC3,,CCO,O,[K+].[OH-],,test
US03971819,CN(C)CCCN.NS(=O)(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1Cl>>CN(C)CCCNc1c([N+](=O)[O-])cc(C(=O)O)cc1S(N)(=O)=O,,O,,,,test
US20120184540A1,O=[N+]([O-])c1ccccc1F.OCC(F)F>>O=[N+]([O-])c1ccccc1OCC(F)F,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20030008901A1,O=S(=O)([O-])c1ccc(OCc2ccccc2)cc1.O=S(Cl)Cl>>O=S(=O)(Cl)c1ccc(OCc2ccccc2)cc1,,CN(C)C=O,,[Na],,test
US04760086,CC=C(c1ccccc1)c1ccccc1.O=C(OO)c1cccc(Cl)c1>>CC1OC1(c1ccccc1)c1ccccc1,,ClCCl,,,,test
US20040138211A1,COC(=O)CC(=O)OC.O=Cc1ccc(OCCOc2ccc3ncccc3c2)cc1>>COC(=O)C(=Cc1ccc(OCCOc2ccc3ncccc3c2)cc1)C(=O)OC,,Cc1ccccc1,,C1CC[NH2+]CC1.CC(=O)[O-],,test
US20120035168A1,Cc1cc(NC(=O)OC(C)(C)C)nc(C)c1CNC(=O)c1nc(Cc2ccccc2)no1>>Cc1cc(N)nc(C)c1CNC(=O)c1nc(Cc2ccccc2)no1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090137595A1,CC1CC1C(=O)Nc1cn2nc(I)ccc2n1.Nc1ccc(S)cc1>>Nc1ccc(Sc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070010515A1,COc1ccc([C@H](C)N)cc1.N#CN=C(Oc1ccccc1)Oc1ccccc1>>COc1ccc([C@H](C)N=C(NC#N)Oc2ccccc2)cc1,,CC(C)O,,,,test
US20110112103A1,Cc1nc(CC2CCN(c3ccc4sccc4c3)CC2)nc(C(=O)OC(C)(C)C)c1OCc1ccccc1>>Cc1nc(CC2CCN(c3ccc4sccc4c3)CC2)nc(C(=O)O)c1OCc1ccccc1,,C1CCOC1,CO,Cl,[K+].[OH-],test
US04064259,C=CCCCCNC(=O)c1cnc(SCC)s1.OO>>C=CCCCCNC(=O)c1cnc(S(=O)CC)s1,,CC(=O)O,,,,test
US05703106,CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O.Fc1nc(F)nc(F)n1>>CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)F,,ClCCl,,c1ccncc1,,test
US20030225283A1,CON.CS(=O)(=O)c1ccc(C(CC2CCC(=O)CC2)C(=O)Nc2cnc(Br)cn2)cc1Cl>>CON=C1CCC(CC(C(=O)Nc2cnc(Br)cn2)c2ccc(S(C)(=O)=O)c(Cl)c2)CC1,,CO,c1ccncc1,Cl,,test
US20140038976A1,O=C1c2cccnc2C2CNCCN12.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1Br>>O=C1c2cccnc2C2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3Br)CCN12,,ClCCl,,CCN(C(C)C)C(C)C,,test
US03994941,O=C1NC(=O)c2ccccc21.O=[N+]([O-])c1ccc2c(c1)C(c1ccccc1Cl)=NCc1nnc(CCO)n1-2>>O=C1c2ccccc2C(=O)N1CCc1nnc2n1-c1ccc([N+](=O)[O-])cc1C(c1ccccc1Cl)=NC2,,C1COCCO1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04820715,CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1O.COC(C)CCO>>CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCCC(C)OC,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080027053A1,CCOP(=O)(OCc1ccccc1)OC(C)OC(=O)N(C[C@H]1CN(c2ccc(N3Cc4cn(C)nc4C3)c(F)c2)C(=O)O1)C(C)=O>>CCOP(=O)(O)OC(C)OC(=O)N(C[C@H]1CN(c2ccc(N3Cc4cn(C)nc4C3)c(F)c2)C(=O)O1)C(C)=O,[Pd],CO,,[H][H],,test
US20090004209A1,COC(=O)c1cccc(O)c1C(=O)OC.COc1ccc(CBr)cc1>>COC(=O)c1cccc(OCc2ccc(OC)cc2)c1C(=O)OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040116424A1,CCCCn1c(-c2ccccc2)nc(C=O)c1N(Cc1ccc2c(c1)OCO2)Cc1ccc2c(c1)OCO2.NS(=O)(=O)O>>CCCCn1c(-c2ccccc2)nc(C(=O)O)c1N(Cc1ccc2c(c1)OCO2)Cc1ccc2c(c1)OCO2,,O,,[Na+].[O-]Cl,,test
US20030105081A1,COC(=O)c1c[nH]c2c1-c1ncccc1CNC2.O=Cc1ccccc1>>COC(=O)c1c[nH]c2c1-c1ncccc1CN(Cc1ccccc1)C2,,CC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070149568A1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.Cc1ccc(COC(=O)N2CCC(=O)C(F)C2)cc1>>CCOC(=O)/C=C1/CCN(C(=O)OCc2ccc(C)cc2)CC1F,,Cc1ccccc1,,,,test
US20110003787A1,COC[C@H](C)Oc1cc(Oc2ccc(S(=O)(=O)N(C)Cc3ccc(OC)cc3)nc2)cc(-c2ccc(C3=NC[C@H](CO)O3)[nH]2)c1>>CNS(=O)(=O)c1ccc(Oc2cc(O[C@@H](C)COC)cc(-c3ccc(C4=NC[C@H](CO)O4)[nH]3)c2)cn1,,O=C(O)C(F)(F)F,,,,test
US04625047,C=O.CC(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl.CNC.Cl>>CN(C)CCCc1ccc(OCC(=O)O)c(Cl)c1Cl.Cl,,CCO,,CC(=O)O,,test
US20010025045A1,CN1C(=O)c2cccc([N+](=O)[O-])c2C1=O>>CN1Cc2cccc(N)c2C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04324796,Cc1ccc(S(=O)(=O)Cl)cc1.OCCCc1cccc(Cl)c1>>Cc1ccc(S(=O)(=O)OCCCc2cccc(Cl)c2)cc1,,ClC(Cl)Cl,O,Cl,c1ccncc1,test
US20080009515A1,C#C[Si](C)(C)C.COCOc1cc(I)ccc1C>>C#Cc1ccc(C)c(OCOC)c1,[Cu]I,CCOCC,,CC#N,CCN(CC)CC,test
US04921855,CN(CC=O)C(=O)OC(C)(C)C.COC(=O)CN>>COC(=O)CNCCN(C)C(=O)OC(C)(C)C,,CO,,Cl,[BH3-]C#N.[Na+],test
US20090082367A1,CC(C)(c1cc(C=O)c(C(F)(F)F)s1)c1nnc(C2CC2)n1C1CC1.Cl.NO>>CC(C)(c1cc(C#N)c(C(F)(F)F)s1)c1nnc(C2CC2)n1C1CC1.Cl,,CCO,,CCN(CC)CC,,test
US20110021573A1,CCOC(=O)Cc1ccc(OCC)c(-c2ccc(C(F)(F)F)cc2CN2C(=O)O[C@H](c3ccccc3)[C@@H]2C)c1>>CCOc1ccc(CC(=O)O)cc1-c1ccc(C(F)(F)F)cc1CN1C(=O)O[C@H](c2ccccc2)[C@@H]1C,,CO,,[Li+].[OH-],,test
US20140018347A1,Cc1nc(CO)nc(N2CCOc3ccc(Br)cc3C2)c1C(C)C>>Cc1nc(C=O)nc(N2CCOc3ccc(Br)cc3C2)c1C(C)C,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05747499,COC(=O)[C@H](CCC1=NNN(OC)N1C=C=O)NC(=O)OCc1ccccc1>>COC(=O)Cn1nnc(CC[C@H](N)C(=O)OC)n1,[Pd],CCOC(C)=O,,,,test
US20060252750A1,O=C(O[C@H](Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)N1CCN(C2CCN(Cc3ccccc3)CC2)CC1)N1CCC(N2CCc3ccccc3NC2=O)CC1>>O=C(O[C@H](Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)N1CCN(C2CCNCC2)CC1)N1CCC(N2CCc3ccccc3NC2=O)CC1,[Pd],CO,,[H][H],,test
US20100010040A1,OC(c1ccccc1)(c1ncnn1CN1CCCC1)C1CCCCC1>>OC(c1ccccc1)(c1nc[nH]n1)C1CCCCC1,,CCO,,[BH4-].[Na+],,test
US20140221335A1,CCOC(=O)Cl.N#Cc1ccc(C2NC(=O)N(c3cccc(C(F)(F)F)c3)C3=C2C(=O)CC3)cc1>>CCOC(=O)N1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US05587389,COc1c(SCc2cccs2)ccnc1CCl.Sc1nc2ccccc2[nH]1>>COc1c(SCc2cccs2)ccnc1CSc1nc2ccccc2[nH]1,,CCO,,Cl,[Na+].[OH-],test
US20110015181A1,CCOC(=O)c1cc(O)cc(COC2CCCCO2)n1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1cc(OS(=O)(=O)C(F)(F)F)cc(COC2CCCCO2)n1,,ClC(Cl)Cl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US05969137,CC(C)c1ccc(CC#N)cc1.CCO.Cl>>CC(C)c1ccc(CC(=N)O)cc1.Cl,,CCOCC,,,,test
US20130079306A1,Cc1ccccc1-c1nc(C)c(CO)s1.Cn1cnc2cc(C(=O)O)ccc21.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cc1ccccc1-c1nc(C)c(COC(=O)Nc2ccc3c(c2)ncn3C)s1,,Cc1ccccc1,,CCN(CC)CC,,test
US20080027090A1,CC(=O)OC(C)=O.Nc1cc2c3c(c1)c1c(n3CC2)CCCCC1>>CC(=O)Nc1cc2c3c(c1)c1c(n3CC2)CCCCC1,,CC(Cl)Cl,,,,test
US20110190278A1,C1=C(c2ccccc2)CCNC1.CC(C)(C)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC=C(c2ccccc2)CC1,,CC#N,,CCN(CC)CC,Cl,test
US20120142717A1,CCOC(=O)C(C=O)Cc1ccc(C#N)cc1.NC(N)=S>>N#Cc1ccc(Cc2c[nH]c(=S)[nH]c2=O)cc1,,CCO,,,,test
US20140200216A1,C[C@@H]1C[C@H](NC(=O)OC(C)(C)C)CN(c2ccncc2NC(=O)c2nc3cc(N4CCOCC4)ccc3cc2NC(=O)OCc2ccccc2)C1.Cl>>C[C@@H]1C[C@H](N)CN(c2ccncc2NC(=O)c2nc3cc(N4CCOCC4)ccc3cc2NC(=O)OCc2ccccc2)C1.Cl,,C1COCCO1,CO,,,test
US06114325,CCCCCCCCCCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCCN(CCCC)CCCC.Cl>>CCCCCCCCCCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCCN(CCCC)CCCC.Cl,,CCOC(C)=O,,,,test
US05104867,COS(=O)(=O)F.COc1ccc(CS[C@H]2C[C@@H](C(N)=O)N(CCO)C2)cc1>>COc1ccc(CS[C@H]2C[C@@H](C(N)=O)[N+](C)(CCO)C2)cc1.O=S(=O)([O-])F,,ClCCl,,,,test
US20070244173A1,Cc1nc2c3c(ccc2n1C)C(=O)[C@H](OC(=O)C(C)(C)C)[C@@H](c1ccccc1)O3>>Cc1nc2c3c(ccc2n1C)C(O)C(OC(=O)C(C)(C)C)C(c1ccccc1)O3,,CO,,[BH4-].[Na+],,test
US20060142265A1,BrBr.Nc1ncccc1C=O>>Br.Nc1ncc(Br)cc1C=O,,CC(=O)O,,,,test
US20080221195A1,CON(C)C(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C.C[Mg]Br>>CC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C,,C1CCOC1,,,,test
US20100168151A1,FC(F)Cl.O=Cc1ccc(O)c(O)c1>>O=Cc1ccc(OC(F)F)c(O)c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100311966A1,CCO[C@@H]1CNCC[C@@H]1NC(=O)c1nc(Cl)c(CC)[nH]1.Oc1cc(Cl)ccn1>>CCO[C@@H]1CN(c2cc[nH]c(=O)c2)CC[C@@H]1NC(=O)c1nc(Cl)c(CC)[nH]1,,CS(C)=O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20150218181A1,CI.COCC(O)Cn1cc(-c2ccc3cnc(Cl)cc3c2)cn1>>COCC(Cn1cc(-c2ccc3cnc(Cl)cc3c2)cn1)OC,,C1CCOC1,,[H-].[Na+],,test
US20130150364A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](C=O)CC1.CCOC(C)=O>>CCOC(=O)/C=C/[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1,,C1CCOC1,,O,[H-].[Na+],test
US20120270865A2,CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3ccc(OCc4ccccc4)cc3c2C)C(C)C)cn1>>Cc1c(C(Nc2ccc(C(=O)N(C)CCC(=O)O)nc2)C(C)C)oc2ccc(OCc3ccccc3)cc12,,CCO,,[Na+].[OH-],,test
US20150353553A1,CI.C[C@@H]1CC[C@@H](Cn2c(C(C)(O)c3ccccc3F)nc3nc(C#N)nc(-c4cncc(Cl)c4)c32)CC1>>COC(C)(c1ccccc1F)c1nc2nc(C#N)nc(-c3cncc(Cl)c3)c2n1C[C@@H]1CC[C@@H](C)CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20160024026A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=C(NCc1ccc(Br)cc1)OCc1ccccc1>>CC1(C)OB(c2ccc(CNC(=O)OCc3ccccc3)cc2)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US06288278B1,CN(C)C(c1ccccc1)C1CCCCC1=O>>CN(C)C(c1ccccc1)C1CCCCC1O,,CO,,Cl,[BH4-].[Na+],test
US20130273034A1,CC(C)(C)OC(=O)Nc1ccc(CN)cn1.Nc1ccc(S(=O)(=O)N2CCCCC2)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)Nc1ccc(CNC(=O)Nc2ccc(S(=O)(=O)N3CCCCC3)cc2)cn1,,ClCCl,,,,test
US05541324,CC(C)(N)C(=O)O.O=[N+]([O-])c1ccc(F)cc1F>>CC(C)(Nc1cc(F)ccc1[N+](=O)[O-])C(=O)O,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20030144263A1,CC1(C)OC[C@H](C(=O)Cl)O1.O=C1O[C@@H](COc2cnsn2)CN1c1ccc(C2=CCNCC2)c(F)c1>>CC1(C)OC[C@H](C(=O)N2CC=C(c3ccc(N4C[C@H](COc5cnsn5)OC4=O)cc3F)CC2)O1,,ClCCl,,Cl,c1ccncc1,test
US04764522,O=C(O)c1ccccn1.O=S(Cl)Cl>>O=C(Cl)c1ccccn1,CN(C)C=O,Cc1ccccc1,,,,test
US20050065099A1,BrCc1ccccc1.Cc1c(O)ccc(O)c1C>>Cc1cc(O)ccc1OCc1ccccc1,,CC(C)=O,,[I-].[K+],,test
US20050209297A1,CC(C)(C)n1nc(C2CCC2)cc1N.O=C(O)Cc1ccc2ccccc2c1>>CC(C)(C)C1(NC(=O)Cc2ccc3ccccc3c2)C=C(C2CCC2)NN1,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US20100292455A1,CC(C)CCC[C@@H](C)[C@H]1CCC2C3CC=C4CC(OC(=O)Cl)CC[C@]4(C)C3CC[C@@]21C.CCN(CC)CC.COc1ccc(C(OC(c2ccccc2)C2CC(O)CN2C(=O)CCCCCN)c2ccc(OC)cc2)cc1>>CCCCCCCCC1CCC2C3CC=C4CC(OC(=O)NCCCCCC(=O)N5CC(O)CC5C(OC(c5ccc(OC)cc5)c5ccc(OC)cc5)c5ccccc5)CCC4(C)C3CCC12C,,ClCCl,,CO,ClC(Cl)Cl,test
US05039694,Cn1cc(C(=O)NC(C#N)c2ccco2)cn1.S>>Cn1cc(C(=O)NC(C(N)=S)c2ccco2)cn1,,CCN(CC)CC,,CCO,,test
US20140309210A1,CO.O=C(O)c1n[nH]c2cc(Br)ccc12>>COC(=O)c1n[nH]c2cc(Br)ccc12,,CCOC(C)=O,,O=S(=O)(O)O,,test
US04404222,CC(C)(C)NCC(Cl)c1cc(Cl)c(N)c(Cl)c1.CO.Cl>>COC(CN)c1cc(Cl)c(N)c(Cl)c1.Cl,,CCO,,CC(C)O,,test
US20160122344A1,CC(=O)OC(C)=O.CCOc1ccc(CC(CO)NC(=O)OC(C)(C)C)cc1OCC>>CCOc1ccc(CC(COC(C)=O)NC(=O)OC(C)(C)C)cc1OCC,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160046623A1,COc1ncc(C)c(-c2ccc3c(c2)[nH]c(=O)c2cnn([C@H]4CCOC4)c23)c1C.Cc1ccc(S(=O)(=O)O)cc1>>COc1ncc(C)c(-c2ccc3c(c2)[nH]c(=O)c2cnn([C@H]4CCOC4)c23)c1C.Cc1ccc(S(=O)(=O)O)cc1,,CCC(C)=O,,,,test
US20020165234A1,CC(C)(N)Cc1ccc(NS(=O)(=O)c2ccccc2)cc1.c1ccc2c(c1)[nH]c1cccc(OC[C@@H]3CO3)c12>>CC(C)CN(C[C@H](O)COc1cccc2[nH]c3ccccc3c12)c1ccc(NS(=O)(=O)c2ccccc2)cc1,,CCO,,,,test
US05206238,CC(C)COC(=O)Cl.CN1c2ccccc2C(c2ccccc2F)=NCC1CN>>CC(C)COC(=O)C1(C)C(N)N=C(c2ccccc2F)c2ccccc2N1C,,ClCCl,,CN1CCOCC1,,test
US20140114067A1,CCN1CCCC1CN.O=C(O)c1ccc(Cn2c(Cc3c(Cl)cccc3Cl)nc3ccccc32)cc1>>CCN1CCCC1CNC(=O)c1ccc(Cn2c(Cc3c(Cl)cccc3Cl)nc3ccccc32)cc1,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US04080207,CC(=O)NNc1ccc(N)cc1.O=C(CCl)c1ccccc1.S=C=S>>CC(=O)NNc1ccc(N2C(=S)SCC2(O)c2ccccc2)cc1,,CO,,CC(=O)[O-].[K+],,test
US20090181928A1,C[Si](C)(C)CCN1C(=O)CN(c2ccc(CCN)cc2OCc2ccccc2)S1(=O)=O.O=C=NC1CCCCC1>>C[Si](C)(C)CCN1C(=O)CN(c2ccc(CCNC(=O)NC3CCCCC3)cc2OCc2ccccc2)S1(=O)=O,,C1COCCO1,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US04757081,CCCI.Cc1c(-c2ccc(O)cc2)n(-c2ccccc2)c(-c2ccccc2)cc1=O>>CCCOc1ccc(-c2c(C)c(=O)cc(-c3ccccc3)n2-c2ccccc2)cc1,,CS(C)=O,,[H-].[Na+],,test
US20080070960A1,COc1cc(OC)c(-c2noc3ccccc23)cc1CNc1ccccc1>>Oc1cc(O)c(-c2noc3ccccc23)cc1CNc1ccccc1,,ClCCl,,BrB(Br)Br,,test
US04374137,CN1CC(=O)c2ccccc2C1.Fc1ccccc1CCl>>CN1Cc2ccccc2C(O)(Cc2ccccc2F)C1.Cl,,CCOCC,,II,[Mg],test
US04627933,CCOc1ccc(CC(=O)OCc2ccc(C(N)=O)cc2)cc1>>CCOc1ccc(CC(=O)OCc2ccc(C#N)cc2)cc1,,CN(C)C=O,,O=P(Cl)(Cl)Cl,,test
US20090181967A1,CC(C)(C)OC(=O)N1CCOCC1COC(=O)N1CCN(c2ccccc2)CC1>>O=C(OCC1COCCN1)N1CCN(c2ccccc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06127382,CCOC(=O)c1ccc(NCc2cc3c(cc2C)N(C(C)C)CCC3(C)C)cc1>>Cc1cc2c(cc1CNc1ccc(C(=O)O)cc1)C(C)(C)CCN2C(C)C,,CCO,,[K+].[OH-],,test
US20080269302A1,COC(=O)c1cc(OS(C)(=O)=O)cc(C(=O)OC)c1>>COC(=O)c1cc(OS(C)(=O)=O)cc(C(=O)O)c1,,C1CCOC1,,[Na+].[OH-],,test
US20150344473A1,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.O=S(=O)(c1ccccc1)n1c(I)cc2c(Cl)ncnc21>>Cn1cc(-c2cc3c(Cl)ncnc3[nH]2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20070276011A1,COCOc1cc(CO[Si](C)(C)C(C)(C)C)cc(OCOC)c1C(=O)OC>>COCOc1cc(CO)cc(OCOC)c1C(=O)OC,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20160221945A1,Cl.N#Cc1cc(F)nc(-c2ccc(C(F)(F)F)nc2)c1>>Cl.NCc1cc(F)nc(-c2ccc(C(F)(F)F)nc2)c1,[Pd],C1CCOC1,,,,test
US20040106645A1,ClCc1ccc2c(c1)OCO2.O=c1nc(NC2CC3CCC(C2)N3)c2cc(Cl)ccc2n1CC(F)(F)F>>O=c1nc(NC2CC3CCC(C2)N3Cc2ccc3c(c2)OCO3)c2cc(Cl)ccc2n1CC(F)(F)F,,CN(C)C=O,,CCN(CC)CC,,test
US20060148858A1,CC(=O)OCBr.CCCc1c[nH]nc1OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1CCC>>CCCc1cn(CC(=O)O)nc1OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1CCC,,CN(C)C=O,,O,[H-].[Na+],test
US20140107094A1,CON(C)C(=O)c1cncn1C.Cn1cncc1Br>>Cn1cncc1C(=O)c1cncn1C,,ClCCl,,CC[Mg]Br,,test
US20050277652A1,C1COCCN1.Nc1cc(Oc2ccc([N+](=O)[O-])cc2F)ncn1.O=C(Cl)Oc1ccccc1>>O=C(Nc1cc(Oc2ccc([N+](=O)[O-])cc2F)ncn1)N1CCOCC1,,C1CCOC1,,CCN(CC)CC,,test
US04256748,CCOC(=O)[C@H](C)N.Cc1cccc(CCl)c1[N+](=O)[O-]>>CCOC(=O)[C@H](C)NCc1cccc(C)c1[N+](=O)[O-],,CCO,,CCN(CC)CC,Cl,test
US20100022460A1,CC(C)(N)CO.Cc1cc(OCc2ccccc2)c([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1Cc1ccc(/C=C/CC(=O)O)cc1>>Cc1cc(OCc2ccccc2)c([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1Cc1ccc(/C=C/CC(=O)NC(C)(C)CO)cc1,,ClC(Cl)Cl,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20070078136A1,COc1ccc(CN(c2ccccc2)c2cc(N[C@@H]3CC[C@@H](N)CC3)nn3c(C(N)=O)cnc23)cc1>>NC(=O)c1cnc2c(Nc3ccccc3)cc(N[C@@H]3CC[C@@H](N)CC3)nn12,,O=C(O)C(F)(F)F,,,,test
US20100075994A1,CCOC(=O)C#CC(F)(F)F.NC1=NCC(COc2ccc(C3CCCCC3)cc2)O1>>O=c1cc(C(F)(F)F)n2c(n1)OC(COc1ccc(C3CCCCC3)cc1)C2,,CCO,,,,test
US04116956,Clc1ccc2c(c1)C(c1ccccc1)=NCC(SCc1ccccc1)=N2.NN>>NNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=NC1,,C1CCOC1,CO,O,O,test
US20140315783A1,COC(=O)[C@H](C)NC(=O)c1cc([C@H](O)CO)nc(-c2ccc(Oc3ccc(F)cc3)cc2)n1.N>>C[C@H](NC(=O)c1cc([C@H](O)CO)nc(-c2ccc(Oc3ccc(F)cc3)cc2)n1)C(N)=O,,CO,,,,test
US06069157,N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1-c1cc(Br)no1.O=C1CCC(=O)N1Br>>N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1-c1onc(Br)c1Br,,CC#N,,,,test
US20070149542A1,CCCI.CS(=O)(=O)c1cccc(C2CCNCC2)c1F>>CCCN1CCC(c2cccc(S(C)(=O)=O)c2F)CC1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20090264445A1,CCOC(=O)C=C(C)Cl.Oc1cc(Cl)ccc1Cl>>CCOC(=O)/C=C(\C)Oc1cc(Cl)ccc1Cl,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20130150342A1,O=C(Cl)OCc1ccccc1.c1ccc(CCN2CCC[C@@H]3CCN[C@@H]3C2)cc1>>O=C(OCc1ccccc1)N1CC[C@H]2CCCN(CCc3ccccc3)C[C@H]21,,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20080085886A1,ON=Cc1cncc(F)c1Cl>>N#Cc1cncc(F)c1Cl,,ClCCl,,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US20030092677A1,Cc1cc(F)ccc1-c1ccc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3ccnc3)c2)c1>>Cc1cc(F)ccc1-c1ccc2c(c1)NC(=O)CC(c1cccc(-n3ccnc3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US04735650,Nc1cc(F)cc(F)c1.Nc1ccnnc1.O=C(Cl)OC(Cl)(Cl)Cl>>O=C(Nc1ccnnc1)Nc1cc(F)cc(F)c1,,C1COCCO1,,CCN(CC)CC,,test
US20070117798A1,CC(=NO)c1ccc(F)nc1F>>CC(N)c1ccc(F)nc1F,[Zn],O=C(O)C(F)(F)F,,[Na+].[OH-],,test
US20040171881A1,CCc1cccc(C2(NC[C@@H](O)[C@H](Cc3cc(F)cc(F)c3)NC(=O)CCC(=O)O)CC2)c1.CN(C)C=O.ClCCCl.On1nnc2ccccc21>>CCc1cccc(C2(NC[C@@H](O)[C@H](Cc3cc(F)cc(F)c3)NC(=O)CCC(=O)N[C@H]3CN4CCC3CC4)CC2)c1.O=CO,,CN(C)C=O,,,,test
US20150080364A1,CC(C)(C)OC(=O)N1CCN(Cc2ccc(Cl)cc2N2Cc3cccnc3C2)CC1>>Clc1ccc(CN2CCNCC2)c(N2Cc3cccnc3C2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US03978121,CC=C1c2ccccc2C=Cc2ccccc21.O=C1CCC(=O)N1Br>>BrCC=C1c2ccccc2C=Cc2ccccc21,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US03997572,CS(=O)(=O)Cl.Cc1ncc([N+](=O)[O-])n1CCO.O>>CS(=O)(=O)O.Cc1ncc([N+](=O)[O-])n1CCO,,O,,c1ccncc1,,test
US20120251551A1,N#Cc1ccc(Cl)nc1.OCC(F)(F)CO>>N#Cc1ccc(OCC(F)(F)CO)nc1,,CN(C)C=O,,[H-].[Na+],,test
US20140045872A1,FC(F)(F)c1ccncc1Br.O=C1NCCc2cc(Cl)c(C(F)(F)F)cc21>>O=C1c2cc(C(F)(F)F)c(Cl)cc2CCN1c1cnccc1C(F)(F)F,I[Cu]I,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20160205935A1,COc1ccc(B(O)O)cc1C.Cc1csc(Br)n1>>COc1ccc(-c2nc(C)cs2)cc1C,,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20070244132A1,CC(O)(CCO)CCO.O=C(OC(=O)c1ccccc1)c1ccccc1>>CC(O)(CCO)CCOC(=O)c1ccccc1,CN(C)c1ccncc1,CC#N,,c1ccncc1,,test
US20160185740A1,COc1cccc(C(=O)Cl)c1.Nc1ccccc1C(=O)O>>COc1cccc(-c2nc3ccccc3c(=O)o2)c1,,c1ccncc1,,,,test
US20130131039A1,CSc1nc(N)cc(Cl)n1.O=CCCl>>CSc1nc(Cl)cc2nccn12.Cl,,C1COCCO1,,,,test
US08183386B2,CCC(=O)Cl.c1ccc2ccccc2c1>>CCC(=O)c1cccc2ccccc12,,ClCCCl,,Cl,,test
US20090105275A1,CC1(C)OB(c2ccccn2)OC1(C)C.CCOC(=O)C(CC(C)C)c1cc(OS(=O)(=O)C(F)(F)F)cc(-c2ccc(C(F)(F)F)cc2)c1>>CCOC(=O)C(CC(C)C)c1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccccn2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20030191156A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Oc1cccc(C2=NCCN2)c1>>CC(C)(C)OC(=O)N1CCN=C1c1cccc(O)c1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US05622982,O=S(Cl)Cl.OC(Cn1ccnc1)c1ccc(Cl)cn1>>Clc1ccc(C(Cl)Cn2ccnc2)nc1,,Cc1ccccc1,,,,test
US20070155726A1,CNCCN(C)Cc1ccc(C(=O)OC)cc1.O=Cc1ccc(Oc2ccc(-c3ncco3)cc2)cc1>>COC(=O)c1ccc(CN(C)CCN(C)Cc2ccc(Oc3ccc(-c4ncco4)cc3)cc2)cc1,,ClCCl,,O=C([O-])O.[Na+],,test
US20140148453A1,Brc1cncc(Br)c1Br.CO>>COc1c(Br)cncc1Br,,O,,C1CCOC1,[H-].[Na+],test
US06107329,N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(O)CC1.O=C(O)c1cc2cc(Cl)ccc2[nH]1>>O=C(N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(O)CC1)c1cc2cc(Cl)ccc2[nH]1,,,,Cl,,test
US20050203313A1,N#Cc1ccc(CN)cc1.O>>NCc1ccc(C(N)=O)cc1,[Cu],,,,,test
US20110028450A1,CC1(C)OB(C2=CCOCC2)OC1(C)C.COc1cc2c(cc1-c1cccnc1)-c1c(Br)c3c(n1CC2)C(=O)N(C(C)(C)C)CCCC3>>COc1cc2c(cc1-c1cccnc1)-c1c(C3=CCOCC3)c3c(n1CC2)C(=O)N(C(C)(C)C)CCCC3,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20150045378A1,COC=C1CCOC(C)(C)C1>>CC1(C)CC(C=O)CCO1,,C1CCOC1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05929097,CCCCCCCCBr.COC(=O)c1cccc(C=O)c1NS(=O)(=O)c1ccc(OC)cc1>>CCCCCCCCN(c1c(C=O)cccc1C(=O)OC)S(=O)(=O)c1ccc(OC)cc1,,CCOCC,CN(C)C=O,[H-].[Na+],,test
US20120149691A1,CC1CCCCC1Nc1c(C(=O)O)cnn2cccc12.CO>>COC(=O)c1cnn2cccc2c1NC1CCCCC1C,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,Cl,test
US20090209556A1,CCOC(=O)c1ccc(C2=CCC3(CC2)OCCO3)cc1>>CCOC(=O)c1ccc(C2CCC3(CC2)OCCO3)cc1,O=[Pt]=O,CCOC(C)=O,,[H][H],,test
US20030225059A1,CS(=O)(=O)Cl.OCc1cc(OC(F)(F)F)ccc1OC1CC1>>CS(=O)(=O)OCc1cc(OC(F)(F)F)ccc1OC1CC1,,ClCCl,,CCN(CC)CC,O,test
US05116846,O=C(Cl)C(=O)Cl.OC(CC1CCN(Cc2ccccc2)CC1)c1ccc(F)cc1>>O=C(Cc1ccc(F)cc1)C1CCN(Cc2ccccc2)CC1,,ClCCl,,CCN(CC)CC,CS(C)=O,test
US20130230542A1,CNc1ccccc1.Oc1ccc(OCCCCCBr)cc1>>CN(CCCCCOc1ccc(O)cc1)c1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US05744426,Cn1nc(-c2cc(C=C(Cl)C(=O)OC(C)(C)C)c(Cl)cc2Cl)c(Cl)c1OC(F)F>>Cn1nc(-c2cc(C=C(Cl)C(=O)O)c(Cl)cc2Cl)c(Cl)c1OC(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US05852019,C=O.CC(=O)c1cnn(-c2ncccn2)c1C.Cl.Cl.c1cnc(N2CCNCC2)nc1>>Cc1c(C(=O)CCN2CCN(c3ncccn3)CC2)cnn1-c1ncccn1.Cl.Cl,,CCO,,,,test
US20110105462A1,Cc1ccc(S(=O)(=O)Cl)cc1.OC[C@H]1COc2ccc(C(F)(F)F)cc2O1>>Cc1ccc(S(=O)(=O)OC[C@H]2COc3ccc(C(F)(F)F)cc3O2)cc1,CN(C)c1ccncc1,ClCCl,,Cl,,test
US20110306590A1,Brc1ccc2[nH]c(C3CCNCC3)nc2c1.OB(O)C1CC1>>c1cc2[nH]c(C3CCNCC3)nc2cc1C1CC1,,Cc1ccccc1,O,C1CCC(P(C2CCCCC2)C2CCCCC2)CC1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20140364412A1,N#Cc1ccc(Br)cc1O.O=C1OCCO1>>N#Cc1ccc(Br)cc1OCCO,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060235013A1,CCC1(CC)C(=O)N(C(C)C)c2ccc([N+](=O)[O-])cc21>>CCC1(CC)C(=O)N(C(C)C)c2ccc(N)cc21,[Pd],C1CCOC1,CO,,,test
US20150141471A1,Cc1nc(-c2ccc(C(F)(F)F)cc2)c(-c2ccc(Cl)cc2)cc1C(=O)O>>Cc1nc(-c2ccc(C(F)(F)F)cc2)c(-c2ccc(Cl)cc2)cc1CO,,C1CCOC1,,B,CO,test
US05514717,O=C(O)CC(F)(Cl)C(F)(F)Br>>O=C(O)CC(F)=C(F)F,[Zn],,,,,test
US05436247,CCOC(=O)CC(=O)CC(=O)OCC.COc1ccc(C(=O)c2cc(OC)c(OC)cc2N)cc1OC>>CCOC(=O)Cc1nc2cc(OC)c(OC)cc2c(-c2ccc(OC)c(OC)c2)c1C(=O)OCC,,CC(=O)O,,O=S(=O)(O)O,,test
US20120315625A1,COC(=O)CC(CCCCCCCCOC1CCCCO1)=C(CCCCCCCCOC1CCCCO1)CC(=O)OC>>COC(=O)CC(CCCCCCCCO)=C(CCCCCCCCO)CC(=O)OC,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04271164,CS(=O)(=O)Cl.ClCCCl.Nc1nc2ncncc2cc1-c1c(Cl)cccc1Cl>>Cc1ncc2cc(-c3c(Cl)cccc3Cl)c(NS(C)(=O)=O)nc2n1,,ClCCCl,,CCN(CC)CC,,test
US20060122065A1,C#CCOc1ccc(CC(F)C(=O)NCc2ccc(Cl)cc2)cc1OC.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>C#CCOc1ccc(CC(F)C(=S)NCc2ccc(Cl)cc2)cc1OC,,C1CCOC1,,,,test
US20070066617A1,C=C(c1cc(Cl)cc(Cl)c1)C(F)(F)F.CN(C)C=O.COC(=O)c1ccccc1.O=C1CCC(=O)N1Cl>>COC(=O)c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20090082379A1,CC(C)(C)c1ccc(N2C(=O)N(Cc3ccn4oc(=S)nc4c3)C(C)(C)C2=O)cc1.NCCCCN1CCCC1>>CC(C)(C)c1ccc(N2C(=O)N(Cc3ccnc(NC(=O)NCCCCN4CCCC4)c3)C(C)(C)C2=O)cc1,,C1COCCO1,,,,test
US20160194292A1,CCCn1c(CCCc2ccc(-c3cccc(N)n3)cc2)nn(-c2ccc(C(F)(F)F)cc2)c1=O.O=S(=O)(Cl)c1ccccc1>>CCCn1c(CCCc2ccc(-c3cccc(NS(=O)(=O)c4ccccc4)n3)cc2)nn(-c2ccc(C(F)(F)F)cc2)c1=O,,ClCCl,,c1ccncc1,,test
US05143920,COc1cccc2c(Cl)c(C(=O)C(C)C)cnc12.Cc1cc(O)ccc1N>>COc1cccc2c(Nc3ccc(O)cc3C)c(C(=O)C(C)C)cnc12,,C1COCCO1,,,,test
US04352792,CC(C)C(=O)Cl.COc1cc(O)c2c(=O)c(OC)c(-c3ccc(OC(=O)C(C)(C)C)c(OC)c3)oc2c1>>COc1cc(OC(=O)C(C)C)c2c(=O)c(OC)c(-c3ccc(OC(=O)C(C)(C)C)c(OC)c3)oc2c1,,c1ccncc1,,,,test
US20080027049A1,CC(C)(C)OC(=O)NCC(=O)Nc1ccc2oc3c(c2c1)CCCCC3>>NCC(=O)Nc1ccc2oc3c(c2c1)CCCCC3,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090131399A1,CI.O=S(=O)(NCC1CCCO1)c1ccc(Br)cc1>>CN(CC1CCCO1)S(=O)(=O)c1ccc(Br)cc1,,C1CCOC1,,[H-].[Na+],,test
US20130217680A1,CC1CN(CCc2ccc3c(c2)CC(C)OC3=O)CCN1.O=C(O)Cc1ccc(-n2cnnn2)cc1>>CC1Cc2cc(CCN3CCN(C(=O)Cc4ccc(-n5cnnn5)cc4)C(C)C3)ccc2C(=O)O1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080292588A1,CCOC(=O)CC1=Nc2ccc([N+](=O)[O-])cc2S(C)(=O)=N1.COC(=O)[C@@H]1[C@H]2CC[C@H](O2)[C@@H]1NCc1ccc(F)cc1>>COC(=O)C1C2CCC(O2)C1N(Cc1ccc(F)cc1)C(=O)CC1=Nc2ccc([N+](=O)[O-])cc2S(C)(=O)=N1,,Cc1ccccc1,,CCN(CC)CC,,test
US20160102081A1,O=C=Nc1ccc(Cl)c(C(F)(F)F)c1.[C-]#[N+]c1cnc(N)c(-c2cc3cc(N)ccc3s2)c1>>[C-]#[N+]c1cnc(N)c(-c2cc3cc(NC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)ccc3s2)c1,,C1CCOC1,CCOC(C)=O,,,test
US20110124634A1,CCOC(=O)C=O.Nc1nc(Cl)c(N)c(NCc2cc3c(cc2Cl)OCO3)n1>>Nc1nc(Cl)c2ncc(=O)n(Cc3cc4c(cc3Cl)OCO4)c2n1,,CC(=O)O,CCO,Cc1ccccc1,,test
US04627871,CC(C)(C)C(=O)Cl.Nc1ccc(O)cc1>>CC(C)(C)C(=O)Nc1ccc(O)cc1,,C1CCOC1,,CCN(CC)CC,O,test
US20040110945A1,COC(=O)Cc1ccc(N)c(Cl)c1.Cc1ccc2nc(Br)sc2c1>>COC(=O)Cc1ccc(Nc2nc3ccc(C)cc3s2)c(Cl)c1,,Cc1ccccc1C,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US06518257B1,CCC(=O)Cl.Nc1cccc(Br)c1>>CCC(=O)Nc1cccc(Br)c1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,O,test
US20090029965A1,O=[N+]([O-])c1ccccc1NC1CCCCC1>>Nc1ccccc1NC1CCCCC1,,CO,,Cl[Sn]Cl,,test
US20100267712A1,O=C1c2cc([N+](=O)[O-])ccc2CN1c1ccc2ccsc2c1>>Nc1ccc2c(c1)C(=O)N(c1ccc3ccsc3c1)C2,[Fe],O,,CO,[Cl-].[NH4+],test
US20120178708A1,CCOc1cc([C@@H](CS(C)(=O)=O)N2C(=O)c3cccc(NC(=O)CO)c3C2=O)ccc1O>>CS(=O)(=O)C[C@H](c1ccc(O)c(O)c1)N1C(=O)c2cccc(NC(=O)CO)c2C1=O,,ClCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20160159808A1,CCOC(=O)C(OCC)OCC>>CCOC(OCC)C(=O)O,,CCO,,[Na+].[OH-],,test
US20120129890A1,COc1ccc(NC(=O)OC(C)(C)C)c(CC(O)C(C)(C)C)c1>>COc1ccc(N)c(CC(O)C(C)(C)C)c1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20040132727A1,COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.COc1cccc(OCCCO)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cccc(OCCCOC(=O)Nc2ccc(Oc3ncnc4cc(OC)c(OC)cc34)cc2)c1,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20120059015A1,C#CC(OCC)OCC.Clc1cccc(I)c1>>CCOC(C#Cc1cccc(Cl)c1)OCC,,CCN(CC)CC,,,,test
US20030069236A1,COC(=O)CC1CN(c2ccccc2)c2cc([N+](=O)[O-])ccc2O1.Cl>>COC(=O)CC1CN(c2ccccc2)c2cc(N)ccc2O1.Cl,[Pd],CO,,,,test
US20130096113A1,COc1ccc(N)c([N+](=O)[O-])c1.CSc1nc2ccc(C=O)cc2o1>>COc1ccc(NCc2ccc3nc(SC)oc3c2)c([N+](=O)[O-])c1,,ClCCl,,O=C(O)C(F)(F)F,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05700446,CN1[C@H]2CC[C@@H]1[C@@H](CO)[C@@H](c1ccc(I)cc1)C2.O=C(O)[C@@H](O)[C@H](O)C(=O)O>>CN1[C@H]2CC[C@@H]1[C@@H](CO)[C@@H](c1ccc(I)cc1)C2.O=C(O)[C@@H](O)[C@H](O)C(=O)O,,CO,,,,test
US20040014753A1,C=CCC1CCCC(C(=O)OC)N1C(=O)OC(C)(C)C>>C=CCC1CCCC(C(=O)OC)N1,,CO,,O=S(Cl)Cl,,test
US20100216836A1,BrCC1COc2ccccc2O1.Fc1cccc(C2CCCNC2)c1>>Fc1cccc(C2CCCN(CC3COc4ccccc4O3)C2)c1,,CC#N,,CCN(CC)CC,,test
US20080194640A1,CC(C)c1ccc(N(Cc2cn[nH]c2)C(=O)[C@H]2CCCc3c(OCc4ccccc4)cccc32)cn1.CCI>>CCn1cc(CN(C(=O)[C@H]2CCCc3c(OCc4ccccc4)cccc32)c2ccc(C(C)C)nc2)cn1,,Cc1ccccc1,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20040044222A1,CC(C)(C)OC(=O)NCCNc1ccc([N+](=O)[O-])cc1.O=C(O)C(F)(F)F>>O=C(NCCNc1ccc([N+](=O)[O-])cc1)C(F)(F)F,,O=C(O)C(F)(F)F,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US09248117B2,CC(=O)OCC(CS(=O)(=O)CCC(C)(C)NC(=O)OCc1ccccc1)OC(C)=O>>CC(=O)OCC(CS(=O)(=O)CCC(C)(C)N)OC(C)=O,[Pd],CO,,,,test
US20110015157A1,C=CC[C@]1(c2ccc(F)cc2)CCN([C@@H](C)c2ccc(OC(F)F)cc2)C(=O)O1.O>>C[C@@H](c1ccc(OC(F)F)cc1)N1CC[C@](CCCO)(c2ccc(F)cc2)OC1=O,,C1CCOC1,ClCCl,,,test
US04610991,C1CCNCC1.O=c1[nH]c2ccccc2c(=O)o1>>Nc1ccccc1C(=O)N1CCCCC1,,Cc1ccccc1,,,,test
US06573337B1,CC1(C)CC(=O)C(=C(O)CCCCC(=O)OCc2ccccc2)C(=O)C1>>CC1(C)CC(=O)C(=C(O)CCCCC(=O)O)C(=O)C1,[Pd],CO,,,,test
US20100311777A1,CCON1CCC(N)(C#N)CC1.Cc1cc(C)c(CC(=O)Cl)c(C)c1>>CCON1CCC(C#N)(NC(=O)Cc2c(C)cc(C)cc2C)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05863944,NCCCCCCCC(=O)O.O=c1[nH]c2ccc(F)cc2c(=O)o1>>Nc1ccc(F)cc1C(=O)NCCCCCCCC(=O)O,,C1COCCO1,O,Cl,O=C([O-])[O-].[K+].[K+],test
US05739336,CI.COC(=O)c1cc2c(cc1O)OCO2>>COC(=O)c1cc2c(cc1OC)OCO2,,CN(C)C=O,,[H-].[Na+],,test
US20050009764A1,Fc1ccc(-c2c[nH]cn2)cn1.O=C1NC(=O)c2ccccc21.O=C1c2ccccc2C(=O)N1CCCCBr>>O=C1c2ccccc2C(=O)N1CCCCCn1cnc(-c2ccc(F)nc2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100048571A1,CC(C)(C)[SiH2]OC(C)(C)c1cncc(Br)c1.CON(C)C(=O)c1ccc(F)cc1>>CC(C)(C)[SiH2]OC(C)(C)c1cncc(C(=O)c2ccc(F)cc2)c1,,CCOCC,,[Li]CCCC,,test
US04163784,NC(=O)c1cccnc1.O=C(Cl)C(=O)Cl>>O=C=NCc1cccnc1,,ClCCCl,,,,test
US20060160851A1,O=C(Cl)Oc1ccc(Cc2ccc(C(F)(F)F)cc2)cc1.O=C(O)Cc1ccc(CC2CCNCC2)cc1>>O=C(O)Cc1ccc(CC2CCN(C(=O)Oc3ccc(Cc4ccc(C(F)(F)F)cc4)cc3)CC2)cc1,,ClCCl,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US04554275,CI.O=C(O)c1cc2ccccc2cc1O>>COc1cc2ccccc2cc1C(=O)O,,CN(C)C=O,,[H-].[Na+],,test
US20150284370A1,CC=O.COC(=O)c1cc(Br)cc(N[C@@H]2CC[C@@H](N(C)C)CC2)c1C>>CCN(c1cc(Br)cc(C(=O)OC)c1C)[C@@H]1CC[C@@H](N(C)C)CC1,,CC(=O)O,ClCCl,O=C([O-])O.[Na+],,test
US20080318815A1,CCCCCCN(CCCCCC)c1ccc([N+](=O)[O-])cc1>>CCCCCCN(CCCCCC)c1ccc(N)cc1,[Pd],CCOC(C)=O,,,,test
US07947679B2,CCC(C)N.Fc1cccc(Cl)c1-c1c(F)nc2ccncc2c1F>>CCC(C)Nc1c(-c2c(F)cccc2Cl)c(F)nc2ccncc12,CN(C)c1ccncc1,CCOCC,CN(C)C=O,,,test
US20040242508A1,CN.CO[C@@H]1[C@@H](CO)O[C@@H](n2c3ccccc3c3c4c(c5c6ccccc6[nH]c5c32)C(=O)OC4=O)[C@H](O)[C@H]1O>>CO[C@@H]1[C@@H](CO)O[C@@H](n2c3ccccc3c3c4c(c5c6ccccc6[nH]c5c32)C(=O)N(C)C4=O)[C@H](O)[C@H]1O,,C1CCOC1,,,,test
US20160039838A1,C1CO[C@H]2CNC[C@H]2O1.CCOc1cc2ncnc(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)c2cc1NC(=O)/C=C/CBr>>CCOc1cc2ncnc(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)c2cc1NC(=O)/C=C/CN1C[C@H]2OCCO[C@H]2C1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,O,test
US20080194579A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.Cn1c(=O)n(-c2ccc(C(C)(C)C#N)cc2)c2c3cc(-c4cnc5ccccc5c4)ccc3ncc21>>Cn1c(=S)n(-c2ccc(C(C)(C)C#N)cc2)c2c3cc(-c4cnc5ccccc5c4)ccc3ncc21,,C1COCCO1,,,,test
US20030032657A1,CSc1c(F)cc(CBr)cc1F.C[Si](C)(C)OC(C#N)c1ccccc1>>CSc1c(F)cc(CC(=O)c2ccccc2)cc1F,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20160257653A1,N#CCc1cc([N+](=O)[O-])ccc1F>>NCCc1cc([N+](=O)[O-])ccc1F,,C1CCOC1,,B,,test
US20070254869A1,CC(=O)OC(C)=O.CC(C)OC(=O)N1CCCC(NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2cc3c(cc21)CCC3>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2cc3c(cc21)CCC3,,ClCCl,,Cl,c1ccncc1,test
US05885986,CCCNCc1cnc(-c2ncn3c2CN(C)C(=O)c2cc(F)ccc2-3)o1.Cl>>CCCNCc1cnc(-c2ncn3c2CN(C)C(=O)c2cc(F)ccc2-3)o1.Cl,,CCO,,,,test
US20100137372A1,NO.O=Cc1ccc(F)c([N+](=O)[O-])c1>>O=[N+]([O-])c1cc(C=NO)ccc1F,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US05872115,CN(C)c1ccc(C(=O)NC2CCN(C(c3ccccc3)c3ccccc3)CC2)c([N+](=O)[O-])c1>>CN(C)c1ccc(C(=O)NC2CCN(C(c3ccccc3)c3ccccc3)CC2)c(N)c1,[Ni],CCO,,,,test
US20050148631A1,CCOC(=O)Cc1cccc(NS(=O)(=O)c2cccc(Cl)c2C)n1>>Cc1c(Cl)cccc1S(=O)(=O)Nc1cccc(CC(=O)O)n1,,CCO,O,[K+].[OH-],,test
US20130158042A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ncn(-c3ccccc3)n2)C(C)(C)C1.O=C(O)C(F)(F)F>>CC1(C)CNCCN1C(=O)c1ncn(-c2ccccc2)n1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20060235033A1,COc1cc2nccc(Oc3ccc(N)c(C)c3)c2cc1OC.Cc1nc(C(C)N)sc1C.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)NC(C)c4nc(C)c(C)s4)c(C)c3)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20100004208A1,COc1cc(C(=O)c2c(Br)oc3c(OC(C)=O)c(OC)ccc23)cc(OC)c1OC.NCc1ccccc1>>COc1cc(C(=O)c2c(NCc3ccccc3)oc3c(O)c(OC)ccc23)cc(OC)c1OC,,c1ccncc1,,,,test
US20090163488A1,Cc1cc(C(=O)Cl)n(C)n1.Nc1cccc(O)c1>>Cc1cc(C(=O)Nc2cccc(O)c2)n(C)n1,,C1CCOC1,,CCN(CC)CC,,test
US20110245242A1,Nc1cc([N+](=O)[O-])ccc1F.O=C1CCCO1>>O=C1CCCN1c1cc([N+](=O)[O-])ccc1F,,CCOC(C)=O,Cl,,,test
US20080167309A1,CCOC(=O)c1ncsc1N(Cc1ccc(OC)cc1)C(=O)c1c(Cl)cc(Cl)cc1Cl>>CCOC(=O)c1ncsc1NC(=O)c1c(Cl)cc(Cl)cc1Cl,,O=C(O)C(F)(F)F,,COc1ccccc1,,test
US20160122342A1,C=O.CCN(c1cccc2c1CC=CCCc1cc(C)[nH]c(=O)c1CNC2=O)[C@@H]1CC[C@@H](N)CC1.O=S(=O)(OCC(F)F)C(F)(F)F>>CCN(c1cccc2c1CC=CCCc1cc(C)[nH]c(=O)c1CNC2=O)[C@@H]1CC[C@@H](N(C)CC(F)F)CC1,,C1CCOC1,CO,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20040092582A1,CC1(C)Cc2cc(N)c3c(c2C(c2ccccc2)=N1)CC(C)(C)O3.CS(=O)(=O)Cl>>CC1(C)Cc2cc(NS(C)(=O)=O)c3c(c2C(c2ccccc2)=N1)CC(C)(C)O3,,C1CCOC1,O,CCN(CC)CC,[Na+].[OH-],test
US20120088750A1,CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)OCC)CC4)nc3)c(OC)c(Br)c2s1>>CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(C)(C(=O)O)CC4)nc3)c(OC)c(Br)c2s1,,CCO,,[Na+].[OH-],,test
US20120040981A1,CC1(C)NC(=O)c2sc(Br)cc2N1.CC1(C)OB(c2ccnc(F)c2)OC1(C)C>>CC1(C)NC(=O)c2sc(-c3ccnc(F)c3)cc2N1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20090240052A1,CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1N.O=C(Cl)c1cncc(-n2cccc2)c1>>CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cncc(-n2cccc2)c1,,CCN(CC)CC,ClCCl,O=C([O-])O.[Na+],,test
US20120214962A1,Brc1ccc(N(c2ccncc2)c2ccncc2)cc1.c1ccc(Nc2ccccn2)nc1>>c1ccc(N(c2ccc(N(c3ccncc3)c3ccncc3)cc2)c2ccccn2)nc1,,CN(C)C=O,,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US03951971,COc1nc(=O)n(-c2ccc(Cl)cc2)c(=O)[nH]1.N>>COc1nc(=O)n(-c2ccc(Cl)cc2)c(=O)[nH]1.[NH4+],,CO,,,,test
US04086361,Cl.N#CCCCCCC(=NO)c1ccc(Cl)cc1.NCCCl>>Cl.N#CCCCCCC(=NOCCN)c1ccc(Cl)cc1,,CN(C)C=O,,[K+].[OH-],,test
US20070105943A1,CC(C)(C)OC(=O)NCc1ccc(C(=O)NCc2ccc(Oc3cccc(F)c3)s2)cn1.CCO.Nc1cnc(C(=O)O)c(N)n1>>CNc1ccc(C(=O)NCc2ccc(Oc3cccc(F)c3)s2)cn1,,CCO,CCOC(C)=O,Cl,O=C([O-])O.[Na+],test
US20140296208A1,CC(C)(C)c1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1>>CC(C)(C)c1cc(N)c(O)c([N+](=O)[O-])c1,[Pd],CC#N,,O=C[O-].[NH4+],,test
US20110263598A1,Brc1ccc2c(c1)CNCC2.C=O>>CN1CCc2ccc(Br)cc2C1,,O=CO,,,,test
US20060100246A1,CC(C)(C)OC(=O)NC(Cc1ccccc1)c1cc(-c2ccccc2OCc2ccccc2)nc(N)c1C=O>>CC(C)(C)OC(=O)NC(Cc1ccccc1)c1cc(-c2ccccc2OCc2ccccc2)nc(N)c1CO,,CCO,,[BH4-].[Na+],,test
US04381301,C1CCNC1.O=C1Nc2ccccc2N(C(=O)CCl)c2cscc21>>O=C1Nc2ccccc2N(C(=O)CN2CCCC2)c2cscc21,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20060063779A1,CCOC(=N)c1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)cc1.CN1CCNCC1>>CN1CCN(C(=N)c2ccc(C(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)cc2)CC1,,CO,,,,test
US20050032786A1,COC(=O)c1ccccc1S.N#Cc1cccc(N2CCCCC2)n1>>O=c1nc(-c2cccc(N3CCCCC3)n2)sc2ccccc12,,Cc1ccccc1,,CCN(CC)CC,,test
US20120196884A1,Cc1cc(NC(=O)Nc2ccccc2)ccc1N1C(=O)c2ccc(Cl)cc2C1=O>>Cc1cc(NC(=O)Nc2ccccc2)ccc1N,,CCO,,NN,O,test
US20140275043A1,Cc1cccc(COc2cccc([C@H](O)CCNC(=O)OC(C)(C)C)c2)n1>>Cc1cccc(COc2cccc([C@H](O)CCN)c2)n1,,CO,,C1COCCO1,Cl,test
US20100204231A1,C[C@H](N)c1ncc(F)cn1.Fc1c(Cl)nc(Cl)nc1N1CCOCC1>>C[C@H](Nc1nc(Cl)c(F)c(N2CCOCC2)n1)c1ncc(F)cn1,,CCCCO,,CCN(C(C)C)C(C)C,Cl,test
US20150284367A1,CC(C)Oc1cccc(Nc2cc(Cl)nnc2C(N)=O)n1.NCCN>>CC(C)Oc1cccc(Nc2cc(NCCN)nnc2C(N)=O)n1,,CN1CCCC1=O,,[NH4+].[OH-],,test
US06350749B1,CS(=O)(=O)Cl.Cc1c[nH]c2c1C(=O)CC(c1ccccc1)C2>>Cc1cn(S(C)(=O)=O)c2c1C(=O)CC(c1ccccc1)C2,,CN(C)C=O,,[H-].[Na+],,test
US20110034507A1,CCOC(=O)c1cccc(-c2cc3cc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)ccc3n2C(=O)OC(C)(C)C)c1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2[nH]c(-c3cccc(C(=O)O)c3)cc2c1,,C1COCCO1,CCO,[Na+].[OH-],,test
US05686445,O=C(Cl)c1ccc(NC(=O)c2ccccc2Cl)cc1.c1ccc2c(c1)NCCc1cncnc1-2>>O=C(Nc1ccc(C(=O)N2CCc3cncnc3-c3ccccc32)cc1)c1ccccc1Cl,,c1ccncc1,,,,test
US07638625B2,Br.Cc1cc(C[C@@H](OC(=O)N2CCCCC2)C(=O)N2CCC(N3CCOCC3)(N3CCc4ccccc4NC3=O)CC2)cc(C)c1O>>Br.Cc1cc(C[C@@H](OC(=O)N2CCCCC2)C(=O)N2CCC(N3CCOCC3)(N3CCc4ccccc4NC3=O)CC2)cc(C)c1O,,CCCO,,,,test
US20040157886A1,Cc1ccc(CC2CCN(C(=O)C(=O)O)CC2)cc1.Nc1ccc2c(c1)CS(=O)(=O)N2>>Cc1ccc(CC2CCN(C(=O)C(=O)Nc3ccc4c(c3)CS(=O)(=O)N4)CC2)cc1,,CC(C)O,,,,test
US20050096380A1,CCOc1cc2c(cc1C=O)C(C(C)(C)C)=CCC2(C)C.CC[Mg]Cl>>CCOc1cc2c(cc1C(O)CC)C(C(C)(C)C)=CCC2(C)C,,C1CCOC1,CN1CCCN(C)C1=O,,,test
US04956378,c1ccc(COc2ccc(NC3=NN(c4ccccc4)CC3)cc2)cc1>>Oc1ccc(NC2=NN(c3ccccc3)CC2)cc1,[Pd],CCO,,[H][H],,test
US20120040957A1,CC(C)(C)O.COc1ccc2ncc(C(=O)O)cc2n1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COc1ccc2ncc(NC(=O)OC(C)(C)C)cc2n1,,CN(C)C=O,,CCN(CC)CC,,test
US06080769,O=C1OCCC1(Cc1ccncc1)N=C(c1ccccc1)c1ccccc1>>NC1(Cc2ccncc2)CCOC1=O,,C1CCOC1,Cl,,,test
US20070037812A1,CCOC(=O)C=Cc1ccc(Oc2cc(F)cc(OC)c2)cc1C>>CCOC(=O)CCc1ccc(Oc2cc(F)cc(OC)c2)cc1C,[Pd],CCOC(C)=O,,,,test
US20120264753A1,C=C(OCC)c1ncc(OCC)cn1.O=C1CCC(=O)N1Br>>CCOc1cnc(C(=O)CBr)nc1,,CCCCCC,CCOC(C)=O,C1CCOC1,O,test
US20130005707A1,CC(=O)OC(C)=O.Nc1cccc(-c2cccc3nc(Nc4ccccc4)nn23)c1>>CC(=O)Nc1cccc(-c2cccc3nc(Nc4ccccc4)nn23)c1,,ClCCl,,c1ccncc1,,test
US04822787,C=CCOC(=O)N1C[C@@H](SC(C)=O)C[C@H]1COCCNC(N)=O>>C=CCOC(=O)N1C[C@@H](S)C[C@H]1COCCNC(N)=O,,CCOC(C)=O,CO,CC(=O)O,C[O-].[Na+],test
US07176310B1,CC(C)(C)OC(=O)CCNc1ncc(C(=O)Nc2ccc(F)cc2)cn1>>O=C(O)CCNc1ncc(C(=O)Nc2ccc(F)cc2)cn1,,O,O=C(O)C(F)(F)F,Cc1ccccc1,,test
US05998433,CCN(CC)Cc1cc2c(o1)CCN(S(=O)(=O)CCCCCc1ccccc1)C2.Cl>>CCN(CC)Cc1cc2c(o1)CCN(S(=O)(=O)CCCCCc1ccccc1)C2.Cl,,CO,,,,test
US20150274696A1,O=[N+]([O-])c1cc2nsnc2cc1F>>Nc1cc2nsnc2cc1F,[Fe],CCO,,O,[Cl-].[NH4+],test
US05840917,CCOC(=O)c1ccc(Cl)s1.O=S(=O)(Cl)Cl>>CCOC(=O)c1cc(Cl)c(Cl)s1,,CC#N,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20130317003A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.NC(=O)C/C=C/c1ccccc1>>NC(=S)C/C=C/c1ccccc1,,Cc1ccccc1,,,,test
US20040157836A1,Cc1c(Br)ccc(NC(=O)OC(C)(C)C)c1C(=O)O>>Cc1c(Br)ccc(N)c1C(=O)O,,C1COCCO1,Cl,,,test
US20040132727A1,CCOc1ccccc1C(C)O.COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCOc1ccccc1C(C)OC(=O)Nc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20130150409A1,Brc1ccccn1.CC(c1cccc(Cl)c1)C1(C#N)CCC1.O=S(=O)(O)O>>O=C(c1ccccn1)C1(Cc2cccc(Cl)c2)CCC1,,C1CCOC1,,[Li]CCCC,,test
US06025370,CC(=O)OC(C)=O.CCOC(=O)CC(=O)c1ccc(Br)c(C)c1F.COC(OC)N(C)C>>CCOC(=O)C(=CNC1CC1)C(=O)c1ccc(Br)c(C)c1F,,ClCCl,,,,test
US20100286189A1,CCOC(=O)C(C)=O.NNc1ccc([N+](=O)[O-])cc1>>CC(=NNc1ccc([N+](=O)[O-])cc1)C(=O)O,,O,,,,test
US20160095858A1,CC(C)(C)COc1cnn(C(=O)OC(C)(C)C)c1>>CC(C)(C)COc1cn[nH]c1,,ClCCl,,,,test
US20060166342A1,COC(=O)CCc1ccc2c(c1)OCO2.COC=O>>COC(=O)C(C=O)Cc1ccc2c(c1)OCO2,,C1CCOC1,,[H-].[Na+],,test
US20150203515A1,COC(=O)C12CCC(NCc3ccc4cc(O)ccc4c3)(CC1)CC2.CS(=O)(=O)OC1CCCCC1>>O=C(O)C12CCC(NCc3ccc4cc(OC5CCCCC5)ccc4c3)(CC1)CC2,,CN(C)C=O,,Cl,[Na+].[OH-],test
US20100190980A1,Cn1ccc(NC(=O)c2nc(Br)cnc2Sc2ccc(F)cc2)n1.Cn1cnnc1S>>Cn1ccc(NC(=O)c2nc(Sc3nncn3C)cnc2Sc2ccc(F)cc2)n1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20050288357A1,CC1CCCC1(C(=O)O)c1ccc(Cl)cc1.CO>>COC(=O)C1(c2ccc(Cl)cc2)CCCC1,,CO,,O=S(=O)(O)O,O=C([O-])[O-].[Na+].[Na+],test
US04315939,BrCC1CO1.CCOC(=O)c1[nH]c(C)c(C)c1O>>CCOC(=O)c1[nH]c(C)c(C)c1OCC1CO1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040254217A1,N.O=C(O)C=Cc1ccc(F)cc1C(F)(F)F>>NC(=O)C=Cc1ccc(F)cc1C(F)(F)F,,C1CCOC1,CN(C)C=O,O=C(Cl)C(=O)Cl,,test
US06034134,CC1(C)CC(C)(C)CC(C)(NCCCC#N)C1.Cl>>CC1(C)CC(C)(C)CC(C)(N2CCCC2)C1.Cl,[Pd],CCO,,,,test
US05866560,CC(=O)OC(C)=O.CC(=O)OCCCCC[C@@H]1Cc2cc(O)ccc2[C@H]2CC[C@]3(C)C(=O)CC[C@H]3[C@@H]21>>CC(=O)OCCCCC[C@@H]1Cc2cc(OC(C)=O)ccc2[C@H]2CC[C@]3(C)C(=O)CC[C@H]3[C@@H]21,,c1ccncc1,,,,test
US20140221347A1,CC(C)(C)OC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1ncc(N)cc1Br.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1nc(Br)c(N)cc1Br,,CC#N,,,,test
US20160016936A1,CC(C)N.Cc1cc(-c2cn(CCO)c([C@H]3CCN(c4ncnc(N)c4C(C)C)C[C@H]3F)n2)ccc1F>>Cc1cc(-c2cn(CCNC(C)C)c([C@H]3CCN(c4ncnc(N)c4C(C)C)C[C@H]3F)n2)ccc1F,,C1CCOC1,,CCN(C(C)C)C(C)C,CS(=O)(=O)Cl,test
US05099019,C1CNCCN1.CCN(CC)c1nc(Cl)cc(Cl)n1>>CCN(CC)c1nc(Cl)cc(N2CCNCC2)n1,,CCO,,,,test
US20140038999A1,CI.Cc1nccc2c1c(=O)n(C)c1cc(Cl)c(O)cc21>>COc1cc2c3ccnc(C)c3c(=O)n(C)c2cc1Cl,,CN(C)C=O,O,[H-].[Na+],,test
US20060100219A1,COS(=O)(=O)OC.O=C1NCCN1CCNS(=O)(=O)c1cccc(Cl)c1Cl>>CN(CCN1CCNC1=O)S(=O)(=O)c1cccc(Cl)c1Cl,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20050075383A1,C=C(CC(=O)OC)C(=O)OC.COc1ccc(C=NO)cc1OC1CCCC1>>COC(=O)CC1(C(=O)OC)CC(c2ccc(OC)c(OC3CCCC3)c2)=NO1,,C1CCOC1,O,[Na+].[O-]Cl,,test
US20140094462A1,O=C(C[C@@H]1CC=CC[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O[C@H](c2ccccc2)CNC1=O)NCc1ccc(Cl)cc1>>N[C@@H]1CC=CC[C@@H](CC(=O)NCc2ccc(Cl)cc2)C(=O)NC[C@@H](c2ccccc2)OC1=O,,CN(C)C=O,,C1CCNCC1,,test
US04036856,C#CC(CC(=O)CCCCC)N(C)C>>C#CC=CC(=O)CCCCC,,CCOCC,CO,,,test
US20080188528A1,Cc1cnc(F)c(Cc2ccccc2)c1.O>>Cc1c[nH]c(=O)c(Cc2ccccc2)c1,,O,,C1COCCO1,Cl,test
US20100222317A1,NCC1(N2CCCCC2)CC(COCc2ccccc2)C1.O=C(Cl)c1ccc(Cl)cc1Cl>>O=C(NCC1(N2CCCCC2)CC(COCc2ccccc2)C1)c1ccc(Cl)cc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US05244771,COC1=C/C(=C2/C=C(OC)c3ccccc3C2=O)C(=O)c2ccccc21.COc1ccc(O)c2ccccc12>>COc1cc(-c2cc(OC)c3ccccc3c2O)c(O)c2ccccc12,O=[Ag],ClC(Cl)Cl,,,,test
US20120220665A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCC(c1ccccc1)C(O)c1cccc2ccccc12>>CN(CC(c1ccccc1)C(O)c1cccc2ccccc12)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US04250123,C=CCCCCC.CC(CCl)Cc1ccccc1>>CCCCCCCc1ccc(CC(C)CCl)cc1,,ClC(Cl)Cl,,O=S(=O)(O)O,,test
US20080214545A1,CC(C)(C)OC(=O)N1CCC(CCOc2ccc(-n3nc(C(C)(C)C)cc3NC(=O)Nc3ccc(Oc4cccnc4)cc3)cc2)CC1>>CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3cccnc3)cc2)n(-c2ccc(OCCC3CCNCC3)cc2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100035883A1,CCOC(=O)c1cc(F)cc2c1C(=O)C(c1ccc(F)cc1)C(c1nccn1C)N2.NN>>Cn1ccnc1C1Nc2cc(F)cc3c(=O)[nH]nc(c23)C1c1ccc(F)cc1,,CO,,O,,test
US20090291965A1,CCOC(=O)c1cnc(N(C)CCc2ccccc2)s1>>CN(CCc1ccccc1)c1ncc(C(=O)O)s1,,C1COCCO1,,[Li+].[OH-],,test
US20110190278A1,CCOC(=O)C[C@H]1CC[C@@H](NC(C)C)CN1C(=O)OC(C)(C)C.O=C(Cl)OCc1ccccc1>>CCOC(=O)C[C@H]1CC[C@@H](N(C(=O)OCc2ccccc2)C(C)C)CN1C(=O)OC(C)(C)C,,ClC(Cl)Cl,ClCCl,CCN(C(C)C)C(C)C,,test
US06878706B1,CC(C)CNCC(=O)N1CCOCC1.O=C(Br)CBr>>CC(C)CN(CC(=O)N1CCOCC1)C(=O)CBr,,C1CCOC1,,,,test
US20110275560A1,O=C[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OCCBr>>O=C(CCBr)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO,,CO,ClCCl,,,test
US20120238545A1,CCOC(=O)c1nn(-c2ccccc2)c(Br)c1CBr.Sc1ncc[nH]1>>CCOC(=O)c1nn(-c2ccccc2)c(Br)c1CSc1ncc[nH]1,,CC#N,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US05580883,CC(=O)N1CCC(Oc2ccc([N+](=O)[O-])cc2C)CC1.Cl>>CC(=O)N1CCC(Oc2ccc(N)cc2C)CC1.Cl,[Pd],CCO,,,,test
US20140309192A1,NCc1ccc(C(=O)Nc2cc(Cl)c(Cl)cc2N2CCN(CCC(F)(F)F)CC2)c(F)c1F.O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O.OCC1CCNCC1>>O=C(Nc1cc(Cl)c(Cl)cc1N1CCN(CCC(F)(F)F)CC1)c1ccc(CNC(=O)N2CCC(CO)CC2)c(F)c1F,,CN(C)C=O,,,,test
US06271380B1,CCc1nc(Br)c(Br)n1COCc1ccccc1.CN(C)C=O>>CCc1nc(Br)c(C=O)n1COCc1ccccc1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20120238574A1,O=[N+]([O-])c1ccc(OC2CCNC2)cc1.OC(c1ccc(CBr)cc1)(C(F)(F)F)C(F)(F)F>>O=[N+]([O-])c1ccc(OC2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)C2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20020013460A1,NC(N)=O.O=C1Cc2ccccc2C(=O)O1>>O=C1Cc2ccccc2C(=O)N1,,O,,,,test
US20050032786A1,COC(=O)c1ccccc1S.Cc1nc(C#N)cs1>>Cc1nc(-c2nc(=O)c3ccccc3s2)cs1,,Cc1ccccc1,,CCN(CC)CC,,test
US05175284,CC(C)CN1C(=O)C2=C3SC(S(N)(=O)=O)=CC1CC(C2)S3.O=S([O-])OO>>CC(C)CN1C(=O)C2=C3SC(S(N)(=O)=O)=CC1CC(C2)S3(=O)=O,,O,,CO,,test
US06235731B1,COP(=O)(CC(=O)/C=C/C1CCN(C(=O)OC(C)(C)C)CC1)OC>>COP(=O)(CC(=O)CCC1CCN(C(=O)OC(C)(C)C)CC1)OC,[Pd],CO,,,,test
US20100298312A1,CC(=O)Cl.c1ccc(Nc2cc(-c3ccnc(Nc4ccc(-n5ccnn5)cc4)n3)cc(N3CCOCC3)c2)cc1>>CC(=O)Nc1cc(-c2ccnc(Nc3ccc(-n4ccnn4)cc3)n2)cc(N2CCOCC2)c1,,ClCCl,,,,test
US20100190778A1,COc1ccc2c(c1)C=NNS2(=O)=O>>COc1ccc2c(c1)CNNS2(=O)=O,O=[Pt]=O,,,,,test
US20090163524A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(CCCO)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)NC(CCCO)c1ccc(Cl)cc1,,ClCCl,,,,test
US04568687,BrCc1ccccc1.O=C(NCCCn1ccnc1)c1ccccc1>>O=C(c1ccccc1)N(CCCn1ccnc1)Cc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20110313130A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COC(=O)c1cc(Br)cc(C(=O)OC)n1>>COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)cc(C=O)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,[BH4-].[Na+],,test
US20150191483A1,O=S(=O)(c1ccc(F)cc1)[C@@]1(c2ccc(Br)c(F)c2)CCN(Cc2ccccc2)C1>>O=S(=O)(c1ccc(F)cc1)[C@@]1(c2ccc(Br)c(F)c2)CCNC1,,ClCCCl,,CC(Cl)OC(=O)Cl,,test
US20080051418A1,CCOC(=O)CCc1cc(OC(C)C)n[nH]1.FC(F)(F)c1ccc(CBr)cc1>>CCOC(=O)CCc1cc(OC(C)C)nn1Cc1ccc(C(F)(F)F)cc1,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20100178710A1,CC1CCCC(C)N1CC(=O)NCC(=O)O.O=C1CCC(=O)N1O>>CC1CCCC(C)N1CC(=O)NCC(=O)ON1C(=O)CCC1=O,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04307099,CC(=O)SCC(C)C(=O)N1CCC[C@H]1C(=O)OCc1cc2c3ccccc3[nH]c(=O)n2n1>>CC(CS)C(=O)N1CCC[C@H]1C(=O)OCc1cc2c3ccccc3[nH]c(=O)n2n1,,N,,,,test
US20040009983A1,CCOC(=O)C=Cc1ccc2c(c1)c(-c1cc3cccnc3n1S(=O)(=O)c1ccc(C)cc1)cn2C>>CCOC(=O)CCc1ccc2c(c1)c(-c1cc3cccnc3n1S(=O)(=O)c1ccc(C)cc1)cn2C,[Pd],,,,,test
US20090312286A1,CCCCCCBr.Oc1cccc(O)c1>>CCCCCCOc1cccc(O)c1,,CN(C)C=O,O,[H-].[Na+],,test
US03978059,CSC1=NCCN1.O=c1oc(=O)n(Cc2cccs2)c2ccccc12>>O=C1c2ccccc2N(Cc2cccs2)C2=NCCN12,,C1COCCO1,,[K+].[OH-],,test
US20150344466A1,CCOC(=O)c1cc(COc2ccc3c(c2)CCCC3)on1>>O=C(O)c1cc(COc2ccc3c(c2)CCCC3)on1,,O,,CCO,[K+].[OH-],test
US20120035163A1,CCOC(=O)CC1CN=C(c2cc3cc(Oc4ccc(S(C)(=O)=O)nc4)ccc3[nH]2)S1>>CS(=O)(=O)c1ccc(Oc2ccc3[nH]c(C4=NCC(CC(=O)O)S4)cc3c2)cn1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20040034223A1,CCOC(C)=O.OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COC(=O)[C@H]1CC=CC[C@H]1C(=O)O,,c1ccccc1,,CCN(CC)CC,,test
US05723499,CI.COC(=O)c1ccc(-c2ccc3cc4c(cc3c2)C(C)(C)CCC4(C)C)cc1O>>COC(=O)c1ccc(-c2ccc3cc4c(cc3c2)C(C)(C)CCC4(C)C)cc1OC,,CN(C)C=O,,O,[H-].[Na+],test
US20030130286A1,CC(C)(C)OC(=O)NC1CCN(c2ccc(Nc3ncc4ncc(=O)n(C5CCCC5)c4n3)cc2)C1>>CN1CCN(c2ccc(Nc3ncc4ncc(=O)n(C5CCCC5)c4n3)cc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110190340A1,CCOC(=O)C1CC2CSCC(C1)C2=O>>O=C(O)C1CC2CSCC(C1)C2=O,,C1CCOC1,,O,[Na+].[OH-],test
US20100135999A1,CCCCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(OCC(=O)OCc3ccccc3)c3ccc(C)cc3c2)CC1>>CCCCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(OCC(=O)O)c3ccc(C)cc3c2)CC1,[Pd],CCOC(C)=O,,,,test
US04990517,CCOC(=O)N1CC(CO)C(NC)C1>>CNC1CNCC1CO,,O,,,,test
US20090111791A1,CC(C)(C)C1CC(O)CCN1C(=O)O.CC(C)OC(=O)N=NC(=O)OC(C)C.Oc1ccccc1OC(F)(F)F>>CC(C)(C)OC(=O)C1CCN(Oc2ccccc2OC(F)(F)F)CC1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04996206,Cc1cc2c(O)n(I)c(I)nc-2n1>>Cc1cc2c(O)n(I)cnc-2n1,[Zn],CC(=O)O,O,,,test
US06586617B1,COc1ccc(NS(=O)(=O)c2ccc(C)cc2)c([N+](=O)[O-])c1.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc(N(S(=O)(=O)c2ccc(C)cc2)S(=O)(=O)c2ccc(C)cc2)c([N+](=O)[O-])c1,,c1ccncc1,,O,,test
US20090163512A1,COB(C#C[Si](C)(C)C)OC.Cc1ccc(Cl)cc1C1NC(=O)CC(c2cc(Br)ccc2OCC2(C)COC2)C12C(=O)Nc1cc(Cl)ccc12>>Cc1ccc(Cl)cc1C1NC(=O)CC(c2cc(C#C[Si](C)(C)C)ccc2OCC2(C)COC2)C12C(=O)Nc1cc(Cl)ccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20070208056A1,COC(=O)c1cc(Cl)ccc1Br>>OCc1cc(Cl)ccc1Br,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20050130960A1,CC(Cn1ncc2ccc(O)c(Br)c21)NC(=O)OCc1ccccc1.CNCCO>>C[C@@H](Cn1ncc2ccc(O)c(N(C)CCO)c21)NC(=O)OCc1ccccc1,,[Cl-],[NH4+],,,test
US20010049385A1,COC(=O)C1CCCCc2[nH]cnc21.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)C1CCCCc2c1ncn2C(c1ccccc1)(c1ccccc1)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20120122848A1,CC(C)CB(O)O.COc1cc2c(cc1I)C[C@@H]1[C@@H]3CCCC[C@]23CCN1C(=O)OCc1ccccc1>>COc1cc2c(cc1CC(C)C)C[C@@H]1[C@@H]3CCCC[C@]23CCN1C(=O)OCc1ccccc1,,C1COCCO1,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US06579902B1,CO[C@@H]1[C@@H](O)[C@@H](O)C(O)OC1(C)C.Cc1c(O)ccc2c(OC(c3ccccc3)c3ccccc3)cc(=O)oc12>>CO[C@@H]1[C@@H](O)[C@@H](O)[C@H](Oc2ccc3c(OC(c4ccccc4)c4ccccc4)cc(=O)oc3c2C)OC1(C)C,,ClCCl,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06599902B2,Cc1[nH]c(C=O)c(C)c1C(=O)N1CCC[C@@H]1CN1CCCC1.O=C1Cc2cc(S(=O)(=O)Cc3ccccc3OCCN3CCOCC3)ccc2N1>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4ccccc4OCCN4CCOCC4)cc32)c(C)c1C(=O)N1CCC[C@@H]1CN1CCCC1,C1CCNCC1,CCO,,,,test
US05674876,C=C(C)CN(C(C)=O)c1cc(C)c(OC)c(C)c1Br>>COc1c(C)cc2c(c1C)C(C)(C)CN2C(C)=O,[Pd],,,,,test
US20140228349A1,CCOC(=O)CC1(n2cc(-c3nc(-c4cnn(C)c4)cc4nccn34)cn2)CN(S(=O)(=O)C(F)(F)F)C1>>Cn1cc(-c2cc3nccn3c(-c3cnn(C4(CC(=O)O)CN(S(=O)(=O)C(F)(F)F)C4)c3)n2)cn1,,C1CCOC1,,[Li+].[OH-],,test
US05472961,CN(C(=O)Cc1ccc2[nH]c(=O)[nH]c2c1)[C@H](CN1CC[C@H](OCc2ccccc2)C1)c1ccc(OCc2ccccc2)cc1>>CN(C(=O)Cc1ccc2[nH]c(=O)[nH]c2c1)[C@H](CN1CC[C@H](O)C1)c1ccc(O)cc1,,CCOC(C)=O,,[H][H],,test
US20140194469A1,Brc1ccc2cn[nH]c2c1.CON(C)C(C)=O>>CC(=O)c1ccc2cn[nH]c2c1,,C1CCOC1,,[Li]CCCC,,test
US20130096161A1,O=Cc1ccc(O)c(OCCO)c1.O=[N+]([O-])O>>O=Cc1cc(OCCO)c(O)c([N+](=O)[O-])c1,,CC(=O)O,,CCO,,test
US20140038964A1,CC(C)c1ccccc1-c1nc(C(C)(C)O)cn1-c1ccc(Br)cc1.CS(=O)(=O)c1cccc(B(O)O)c1>>CC(C)c1ccccc1-c1nc(C(C)(C)O)cn1-c1ccc(-c2cccc(S(C)(=O)=O)c2)cc1,,CCOC(C)=O,O,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20140329798A1,C1CNC1.COCc1cnc(N2CCC([C@H]3C[C@H]3CCOc3cc(F)c(CC(=O)O)c(F)c3)CC2)nc1>>COCc1cnc(N2CCC([C@H]3C[C@H]3CCOc3cc(F)c(CC(=O)N4CCC4)c(F)c3)CC2)nc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04528114,CCCCCc1ccc(-c2ccc(C#N)cc2)cc1.O=S(=O)(O)O>>CCCCCc1ccc(-c2ccc(C=O)cc2)cc1,,Cc1ccccc1,,CC(C)C[Al+]CC(C)C.[H-],,test
US04493843,CCCCCCCCCCCCCCCCCC(=O)c1c[nH]c2ccc(C(=O)OC)cc12>>CCCCCCCCCCCCCCCCCCC1CNc2ccc(C(=O)OC)cc21,[Pd],CC(=O)O,,[O-][Cl+3]([O-])([O-])O,,test
US20120108619A1,COC(=O)c1cc(C(F)(F)F)c2[nH]ncc2c1>>O=C(O)c1cc(C(F)(F)F)c2[nH]ncc2c1,,C1CCOC1,CO,[Li+].[OH-],,test
US20160221972A1,BrCc1ccccc1.COC(=O)c1ccc2c(c1)S(=O)(=O)NCCO2>>COC(=O)c1ccc2c(c1)S(=O)(=O)N(Cc1ccccc1)CCO2,,O,,CN(C)C=O,[H-].[Na+],test
US20130019348A1,C=C(C)c1ccc(F)cc1[N+](=O)[O-]>>CC(C)c1ccc(F)cc1N,[Pd],CCOC(C)=O,,,,test
US20120184587A1,COc1cc(C(=O)O)cc(C(F)(F)F)c1OCc1ccccc1.O=S(Cl)Cl>>COc1cc(C(=O)Cl)cc(C(F)(F)F)c1OCc1ccccc1,,CN(C)C=O,,Cc1ccccc1,,test
US20040138273A1,CNCCO.Nc1nc(NCCNc2ccc(NC(=O)CBr)c(-c3ccc(Cl)cc3Cl)c2)ccc1[N+](=O)[O-]>>CN(CCO)CC(=O)Nc1ccc(NCCNc2ccc([N+](=O)[O-])c(N)n2)cc1-c1ccc(Cl)cc1Cl,,CC#N,,,,test
US20160158207A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1CCc2c(c(Br)nn2C2CCOC2)C1>>CC(=O)N1CCc2c(c(Br)nn2C2CCOC2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100234389A1,Fc1ccc(-c2cc(N3CCNCC3)ncn2)cc1.O=C([O-])Nc1cccnn1>>O=C(Nc1cccnn1)N1CCN(c2cc(-c3ccc(F)cc3)ncn2)CC1,,C1CCOC1,CCCCCC,,,test
US20030114422A1,CN1C(=O)c2cccc([N+](=O)[O-])c2C1=O>>CN1C(=O)c2cccc(N)c2C1=O,[Pd],CC(=O)O,,[H][H],,test
US20030186995A1,C#C[Si](C)(C)C.CC(C)(C)[SiH2]OC(C)(C)C1CC(=O)CCO1>>CC(C)(C)[SiH2]OC(C)(C)C1CC(O)(C#C[Si](C)(C)C)CCO1,,C1CCOC1,,[Li]CCCC,,test
US20030073731A1,CCOC(=O)C(C(=O)OC(C)(C)C)c1c([N+](=O)[O-])cc([N+](=O)[O-])c2ccccc12>>CCOC(=O)Cc1c([N+](=O)[O-])cc([N+](=O)[O-])c2ccccc12,,CCOC(C)=O,,Cl,,test
US04219657,CCOC(=O)CC1CCC(=O)C(Br)C1.Sc1ccccc1Cl>>CCOC(=O)CC1CCC(=O)C(Sc2ccccc2Cl)C1,,CCO,,[K+].[OH-],,test
US20090221600A1,CSc1ncc2cc(-c3ccccc3C)c(=O)n([C@H]3CCN(C(=O)OC(C)(C)C)C3)c2n1.Cl>>CSc1ncc2cc(-c3ccccc3C)c(=O)n([C@H]3CCNC3)c2n1.Cl,,ClCCl,,,,test
US20110237791A1,COc1nc(/C(=C/CO)c2ccc(C(C)(C)C)cc2)ccc1Cl.Oc1ccccc1>>COc1nc(/C(=C/COc2ccccc2)c2ccc(C(C)(C)C)cc2)ccc1Cl,,C1CCOC1,,CCCCP(CCCC)CCCC,,test
US20090131530A1,COc1ccc(C=O)cc1Oc1cccc(Cl)c1>>COc1ccc(CO)cc1Oc1cccc(Cl)c1,,CO,,[BH4-].[Na+],,test
US20150148313A1,Fc1cc2c(Cl)nccc2cc1N(Cc1ccccc1)Cc1ccccc1.N>>Nc1nccc2cc(N(Cc3ccccc3)Cc3ccccc3)c(F)cc12,,OCCO,,O=C([O-])O.[Na+],,test
US20110263562A1,C[Mg]Cl.O=C(COC1CCN(c2nc3ccc(OCC4CC4)cc3o2)CC1)N1CCOCC1>>CC(=O)COC1CCN(c2nc3ccc(OCC4CC4)cc3o2)CC1,,C1CCOC1,,[Cl-].[NH4+],,test
US04962203,CCCc1cc(O)cc(C=O)c1.COC(=O)CBr>>CCCc1cc(C=O)cc(OCC(=O)OC)c1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06103905,O=C([O-])c1cc(-c2c[nH]c3ccccc23)nc2ccccc12>>O=C(O)c1cc(-c2c[nH]c3ccccc23)nc2ccccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040180912A1,C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1cccc(O)c1.COCCOCCBr>>C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1cccc(OCCOCCOC)c1,,CN(C)C=O,,[H-].[Na+],,test
US20110182812A1,Cc1ccc(S(=O)(=O)OCCCF)cc1.Oc1ccc(-c2ccn3c(n2)nc2ccccc23)cn1>>FCCCOc1ccc(-c2ccn3c(n2)nc2ccccc23)cn1,,CCOC(C)=O,CN1CCCC1=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020022741A1,CCCCC=CCCCCOC(C)=O>>CCCCC=CCCCCO,,CCCCCC,,CO,[Na+].[OH-],test
US20060264473A1,COc1cc(Br)ccc1OCc1ccccc1.O=C1c2ccccc2C(=O)N1CCc1ccccn1>>COc1cc(C2(O)c3ccccc3C(=O)N2CCc2ccccn2)ccc1OCc1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US04906643,COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(CCO)C[C@H]1OC.O=S(Cl)Cl>>COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(CCCl)C[C@H]1OC.O,,c1ccncc1,,ClC(Cl)Cl,,test
US20150344447A1,CCOC(=O)c1cc(O)c(N)cc1[N+](=O)[O-].Cc1ccc(C(=O)Cl)cc1>>CCOC(=O)c1cc(O)c(NC(=O)c2ccc(C)cc2)cc1[N+](=O)[O-],,C1COCCO1,,,,test
US20090170921A1,COc1cccc([N+](=O)[O-])c1N.Cl[Cu]>>COc1cccc([N+](=O)[O-])c1Cl,Cl[Cu],O,,Cl,O=N[O-].[Na+],test
US20060148858A1,COC(=O)CCc1cccc(O)c1.OCCCCc1cc(-c2ccc(C(F)(F)F)cc2)no1>>CC(C(=O)O)c1cccc(OCCCCc2cc(-c3ccc(C(F)(F)F)cc3)no2)c1,,C1CCOC1,Cc1ccccc1,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05217976,CCc1cc(N)c(C=O)c(CC)n1.O=C(O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCc1cc2[nH]c(=O)ccc2c(CC)n1,,Cc1ccccc1,,,,test
US20060063814A1,CON(C)C(=O)c1csc(NC(=O)OC(C)(C)C)n1>>CON(C)C(=O)c1csc(N)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110301181A1,C[Si](C)(C)C(F)(F)F.Cn1nc(OC(F)F)c(I)c1C(=O)Nc1ccc(Cl)c(C(=O)NCC(F)(F)F)c1>>Cn1nc(OC(F)F)c(C(F)(F)F)c1C(=O)Nc1ccc(Cl)c(C(=O)NCC(F)(F)F)c1,[Cu]I,CN(C)C=O,,[F-].[K+],,test
US20110257241A1,COC1(c2ccc(F)c(Cl)c2)CCN(C(=O)OC(C)(C)C)C1>>COC1(c2ccc(F)c(Cl)c2)CCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060287324A1,FC(F)(F)c1ccc(Cc2nnc3cc(-c4ccc(Cl)cc4)c(Br)cn23)cn1.OB(O)c1ccc(Cl)cc1Cl>>FC(F)(F)c1ccc(Cc2nnc3cc(-c4ccc(Cl)cc4)c(-c4ccc(Cl)cc4Cl)cn23)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20150038438A1,CN(C)c1ccc2c(c1)CCCCC2=O.COc1ccc(CN)c(OC)c1>>COc1ccc(CN=C2CCCCc3cc(N(C)C)ccc32)c(OC)c1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,CCN(CC)CC,,test
US20120004198A1,CC(C)(C)OC(=O)Nc1ccc(C(=O)O)cc1.CCOC(=O)C(Cc1ccc(C#N)c(F)c1)NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1.CCOC(=O)C(N)Cc1ccc(C#N)c(F)c1>>CC(C)(C)OC(=O)Nc1ccc(C(=O)NC(Cc2ccc(-c3noc(-c4ccc(NC(=O)OC(C)(C)C)cc4)n3)c(F)c2)C(=O)O)cc1,,ClCCl,,CCN=C=NCCCN(C)C,,test
US20050277674A1,CN(C)C1(c2ccccc2)CCC(CN)CC1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CN(C)C1(c2ccccc2)CCC(CNC(=O)Oc2ccc([N+](=O)[O-])cc2)CC1,,ClCCl,,c1ccncc1,,test
US20130005771A1,COc1ccc(C=Cc2nc(CC3CCN(Cc4ccccc4)CC3)no2)cc1OC>>Oc1ccc(C=Cc2nc(CC3CCN(Cc4ccccc4)CC3)no2)cc1O,,ClCCl,,BrB(Br)Br,,test
US20080032963A1,Cc1cc(Nc2cc(N3CCC3)nc(Sc3ccc(NC(=O)OC(C)(C)C)cc3)n2)n[nH]1>>Cc1cc(Nc2cc(N3CCC3)nc(Sc3ccc(N)cc3)n2)[nH]n1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20050245575A1,CC(C)Cc1ccc(-c2nc(-c3ccc(CO)cc3)no2)cc1.CC[C@H](C)Oc1ccc(C(=O)O)cc1C(F)(F)F>>CC[C@H](C)Oc1ccc(-c2nc(-c3ccc(CO)cc3)no2)cc1C(F)(F)F,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20070010573A1,O=S1(=O)CCCO1.c1ccc(CNCc2ccccc2)cc1>>O=S(=O)(O)CCCN(Cc1ccccc1)Cc1ccccc1,,Cc1ccccc1,,,,test
US20040116694A1,Br.Nc1ccc(C(=O)O)c2c1OCO2>>O=C(O)c1ccc(Br)c2c1OCO2,[Cu]Br,O,,O=N[O-].[Na+],,test
US20020098999A1,CC(C)(C)OC(=O)CC[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H](COCc1ccccc1)C(=O)O>>N[C@@H](CCC(=O)O)C(=O)N[C@H](COCc1ccccc1)C(=O)O,,O=C(O)C(F)(F)F,,,,test
US20090156607A1,Cc1cnc2c(CCl)c(-c3ccccc3)nn2c1.O=C1CC(C=C(F)F)CN1>>Cc1cnc2c(CN3CC(C=C(F)F)CC3=O)c(-c3ccccc3)nn2c1,,O,,CN(C)C=O,[H-].[Na+],test
US20160031903A1,NCC(F)(F)F.O=C1c2ccccc2C(=O)N1CCS(=O)(=O)Cl>>O=C1c2ccccc2C(=O)N1CCS(=O)(=O)NCC(F)(F)F,,ClCCl,,CCN(CC)CC,Cl,test
US08772533B1,C/C=C/C(=O)O.C=C(C(C)O)C(C)C(C)C>>C=C(C(C)OC(=O)C=CC)C(C)C(C)C,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,,,test
US20090281088A1,COc1ccc(COc2nc(O[C@@H]3COc4nc([N+](=O)[O-])cn4C3)ncc2-c2ccc(N3C[C@H](CNC(C)=O)OC3=O)cc2F)cc1>>CC(=O)NC[C@H]1CN(c2ccc(-c3cnc(O[C@@H]4COc5nc([N+](=O)[O-])cn5C4)[nH]c3=O)c(F)c2)C(=O)O1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110201643A1,Cl.O=C(NOC1CCCCO1)c1ccc2c(c1)CCN(C(=O)CCc1cccnc1)C2>>Cl.O=C(NO)c1ccc2c(c1)CCN(C(=O)CCc1cccnc1)C2,,CO,,,,test
US04945158,O=C[C@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1.O=P(C=P(c1ccccc1)(c1ccccc1)c1ccccc1)(Oc1ccccc1)Oc1ccccc1>>O=P(C=C[C@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1)(Oc1ccccc1)Oc1ccccc1,,Cc1ccccc1,,,,test
US20080021032A1,CC(C)(O)Cn1ccc([N+](=O)[O-])n1.CC[Si](Cl)(CC)CC>>CC[Si](CC)(CC)OC(C)(C)Cn1ccc([N+](=O)[O-])n1,,CCOC(C)=O,,CN(C)C=O,c1c[nH]cn1,test
US07622479B2,Nc1nc(Cl)ccc1[N+](=O)[O-].Oc1ccccc1>>Nc1nc(Oc2ccccc2)ccc1[N+](=O)[O-],,CC#N,,C[O-].[Na+],,test
US09439890B2,C#CC(C)(C)C.CC(C)C(=O)NCc1ccc(Cl)c(-n2nc(-c3ccc(I)c(F)c3)[nH]c2=O)c1>>CC(C)C(=O)NCc1ccc(Cl)c(-n2nc(-c3ccc(C#CC(C)(C)C)c(F)c3)[nH]c2=O)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CS(C)=O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090042876A1,CC(=O)O.CCC(=O)[O-].O=c1[nH]c2ccc([N+](=O)[O-])cc2c2cc[nH]c12>>CC(=O)Nc1ccc2[nH]c(=O)c3[nH]ccc3c2c1.CCC(=O)[O-],[Fe],CC(=O)O,,,,test
US05220042,COC1=CC(=O)C(O)=C(CCCCCCCC2OC2CCCCCCCC2=C(O)C(=O)C=C(OC)C2=O)C1=O.[O-][Cl+3]([O-])([O-])O>>COC1=CC(=O)C(O)=C(CCCCCCCC(O)C(O)CCCCCCCC2=C(O)C(=O)C=C(OC)C2=O)C1=O,,C1CCOC1,,CCOCC,,test
US20060052599A1,CC(Cl)OC(=O)Cl.CCOC(=O)/C=C/c1cnc(N[C@@H]2CCN(Cc3ccccc3)C2)c(Cl)c1>>CCOC(=O)/C=C/c1cnc(N[C@@H]2CCNC2)c(Cl)c1.Cl.Cl,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US05594004,COc1ccc(COc2ccc(C#N)cc2)cc1.S>>COc1ccc(COc2ccc(C(N)=S)cc2)cc1,,c1ccncc1,,CCN(CC)CC,,test
US20120122905A1,CC(C)c1noc(N2CCC(O)CC2)n1.Cc1c(Cl)ncnc1Cl>>Cc1c(Cl)ncnc1OC1CCN(c2nc(C(C)C)no2)CC1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20130072519A1,COC(=O)Cc1ccc([N+](=O)[O-])c(C)c1>>COC(=O)Cc1ccc(N)c(C)c1,[Pd],C1CCOC1,,,,test
US20130096113A1,CSc1nc2ccc(CCl)cc2s1.Fc1cnc2[nH]cnc2c1>>CSc1nc2ccc(Cn3cnc4cc(F)cnc43)cc2s1,,CN(C)C=O,,O,[H-].[Na+],test
US20080114003A1,CCOC(=O)Cc1ccccc1OCOC>>COCOc1ccccc1CC(=O)O,,CO,,[Na+].[OH-],,test
US20070117816A1,CCS(=O)(=O)c1cccc(-c2cc(CO)cc3[nH]c4ncc(C)cc4c23)c1.CNC>>CCS(=O)(=O)c1cccc(-c2cc(CN(C)C)cc3[nH]c4ncc(C)cc4c23)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,CS(=O)(=O)Cl,test
US20130210802A1,COC(=O)c1c(-c2ccc3cn[nH]c3c2)cc(Nc2ccc(N3CCOCC3)cn2)c2nccn12>>O=C(O)c1c(-c2ccc3cn[nH]c3c2)cc(Nc2ccc(N3CCOCC3)cn2)c2nccn12,,CCO,,[Na+].[OH-],,test
US04517368,O=P(Cl)(Cl)Cl.Oc1ncc(I)cc1Cl>>Clc1cc(I)cnc1Cl,,ClCCl,,ClP(Cl)(Cl)(Cl)Cl,,test
US20100048550A1,CCOC(=O)CN(C(=O)Oc1ccc(OC)cc1)c1cc(Cl)c(Oc2ccc(OC)c(C(C)CC)c2)c(Cl)c1>>CCC(C)c1cc(Oc2c(Cl)cc(N(CC(=O)O)C(=O)Oc3ccc(O)cc3)cc2Cl)ccc1O,,ClCCl,,BrB(Br)Br,,test
US05965553,Cc1nccn1CCCCN1C(=O)[C@@H](CC#N)O[C@H](c2cccc3ccccc23)c2cc(Cl)ccc21.OO>>Cc1nccn1CCCCN1C(=O)[C@@H](CC(N)=O)O[C@H](c2cccc3ccccc23)c2cc(Cl)ccc21,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20070197624A1,CC(C)(C)NN.CC(C)(C)OC(=O)N1CCC(C(=O)CC#N)(c2ccccc2)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccccc2)(c2cc(N)n(C(C)(C)C)n2)CC1,,CCO,,CCN(CC)CC,Cl,test
US20100004238A1,Cn1c(Cl)cc2ncnc(Cl)c21.Nc1ccc(Oc2cccc3[nH]ccc23)c(Cl)c1>>Cn1c(Cl)cc2ncnc(Nc3ccc(Oc4cccc5[nH]ccc45)c(Cl)c3)c21,,CC(C)O,,O=C([O-])O.[Na+],,test
US20130065913A1,CC1=C(C(N)=O)C(c2ccc(C#N)cc2)n2c(n[nH]c2=O)N1c1cccc(C(F)(F)F)c1>>CC1=C(C#N)C(c2ccc(C#N)cc2)n2c(n[nH]c2=O)N1c1cccc(C(F)(F)F)c1,,C1CCOC1,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US20030195352A1,CCOC(=O)CBr.O=Cc1cc(Br)ccc1O>>CCOC(=O)COc1ccc(Br)cc1C=O,,CN(C)C=O,,Cl,[H-].[Na+],test
US20100261910A1,C#Cc1ccc(N)cc1.Cc1ccc(S(=O)(=O)Oc2ccc(OC(F)(F)F)cc2)cc1>>Nc1ccc(C#Cc2ccc(OC(F)(F)F)cc2)cc1,,CCCCCCC,,,,test
US20080275097A1,Cl.N#Cc1cc(Cl)cc(Oc2c(Cl)ccc3c2cnn3Cc2n[nH]c3nc(N)ccc23)c1>>N#Cc1cc(Cl)cc(Oc2c(Cl)ccc3c2cnn3Cc2n[nH]c3nc([NH3+])ccc23)c1.[Cl-],,CO,ClC(Cl)Cl,,,test
US04447361,Cc1ccc(C(=O)c2ccccc2Nc2ncccc2N)cc1>>Cc1ccc(C2=Nc3cccnc3Nc3ccccc32)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120129844A1,CCOC(=O)c1ccc(N2CCN(C3CCC3)CC2)cc1.COc1cc(CCc2cc(N)n(C(=O)OC(C)(C)C)n2)cc(OC)c1>>COc1cc(CCc2cc(NC(=O)c3ccc(N4CCN(C5CCC5)CC4)cc3)n[nH]2)cc(OC)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20040063944A1,Clc1ccc(C2(c3ccc4nccc(C(Cc5cccc(Cl)c5)Cc5cccc(Cl)c5)c4c3)OCCO2)cc1.Clc1ccc(C2(c3ccc4nccc(CCc5cccc(Cl)c5)c4c3)OCCO2)cc1>>O=C(c1ccc(Cl)cc1)c1ccc2nccc(C(Cc3cccc(Cl)c3)Cc3cccc(Cl)c3)c2c1.O=C(c1ccc(Cl)cc1)c1ccc2nccc(CCc3cccc(Cl)c3)c2c1,,CO,Cl,[NH4+].[OH-],,test
US20070276000A1,Cc1cc2cc(O)ccc2c(Oc2ccc(/C=C/C(=O)O)cc2)c1-c1cccc(O)c1>>Cc1cc2cc(O)ccc2c(Oc2ccc(CCC(=O)O)cc2)c1-c1cccc(O)c1,[Pd],CCO,CCOC(C)=O,,,test
US04639521,CC(=O)C1CC(c2ccncc2)CCC1=O.N#CCC(N)=O>>Cc1[nH]c(=O)c(C#N)c2c1CC(c1ccncc1)CC2,,CCO,,C1CCNCC1,,test
US20030069276A1,CNC(=S)N(c1ccccc1)C1CCN(C(=O)OC(C)(C)C)CC1>>CNC(=S)N(c1ccccc1)C1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090023729A1,CCOC(=O)c1cnc(SC)nc1NC(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)OC.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)c1cnc(S(C)=O)nc1NC(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)OC,,ClC(Cl)Cl,,,,test
US20120122838A1,Clc1cc(Br)c2nccn2n1.OCc1ccccc1>>Clc1cc(OCc2ccccc2)c2nccn2n1,,C1CCOC1,,O,[H-].[Na+],test
US05086053,Cc1cc(C)c(C(=O)Cl)c(C)c1.NNC(N)=S>>Cc1cc(C)c(C(=O)NNC(N)=S)c(C)c1,,CN(C)C=O,c1ccncc1,,,test
US04176184,CC1(C)N=CC2=C3N=C(c4ccc(OCc5ccccc5)cc4)N=C3C(=O)CC2C1=O>>CC1(C)N=CC2=C3N=C(c4ccc(O)cc4)N=C3C(=O)CC2C1=O,[Pd],CO,,[H][H],,test
US20140121198A1,O=[N+]([O-])c1cnc2ccsc2c1N[C@H]1CC2CCC1C2>>Nc1cnc2ccsc2c1N[C@H]1CC2CCC1C2,[Pd],CO,,,,test
US20020143186A1,COC(=O)[C@H](O)CNC(=O)c1ccc(CN(C(=O)Nc2cccc(C(C)(C)C)c2)c2ccc(C3CCCCC3)cc2)cc1>>CC(C)(C)c1cccc(NC(=O)N(Cc2ccc(C(=O)NC[C@@H](O)C(=O)O)cc2)c2ccc(C3CCCCC3)cc2)c1,,CCO,,[Na+].[OH-],,test
US05998624,CNC(=O)c1cc2ccccc2c(-c2ccccc2I)n1.FCCBr>>CN(CCF)C(=O)c1cc2ccccc2c(-c2ccccc2I)n1,,CN(C)C=O,,[H-].[Na+],,test
US20130129677A1,CCOC=CC(=O)C(F)(F)F.N#CCC(N)=S>>N#Cc1ccc(C(F)(F)F)nc1S,,CCO,,CN1CCOCC1,,test
US20160264567A1,Cn1nc(C(F)(F)F)cc1-c1cc(CN2C(=O)c3ccccc3C2=O)c(F)cn1>>Cn1nc(C(F)(F)F)cc1-c1cc(CN)c(F)cn1,,CO,,NN,O,test
US20040006143A1,CC(C)(C)OC(=O)COc1ccc(Oc2ccc(CCN(C[C@H](O)c3cccc(Cl)c3)C(=O)OC(C)(C)C)cc2)cc1.Cl>>Cl.O=C(O)COc1ccc(Oc2ccc(CCNC[C@H](O)c3cccc(Cl)c3)cc2)cc1,,C1COCCO1,,,,test
US05135940,CCCc1c(OCCCSc2ccc(C(=O)CCCCC(=O)OC)cc2)ccc(C(C)=O)c1O>>CCCc1c(OCCCSc2ccc(C(=O)CCCCC(=O)O)cc2)ccc(C(C)=O)c1O,,C1CCOC1,,[Na+].[OH-],,test
US20020115693A1,CC(C)CCN.Cc1nc(C=O)[nH]c1C>>Cc1nc(CNCCC(C)C)[nH]c1C,O=[Pt]=O,CCO,,,,test
US20060089371A1,COC(=O)[C@@H](Cc1ccccn1)Nc1cc(Cl)ncn1.OB(O)c1ccc(OCc2ccccc2)cc1>>COC(=O)[C@@H](Cc1ccccn1)Nc1cc(-c2ccc(OCc3ccccc3)cc2)ncn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,c1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20030060466A1,Fc1ccc(N2CCNCC2)cc1.N#Cc1c(Cl)nc(NCCO)nc1Cl>>N#Cc1c(Cl)nc(NCCO)nc1N1CCN(c2ccc(F)cc2)CC1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20100273744A1,Clc1ccc(OCc2ccccc2)cc1CBr.O=C(Nc1cc[nH]n1)c1c(F)cccc1F>>O=C(Nc1ccn(Cc2cc(OCc3ccccc3)ccc2Cl)n1)c1c(F)cccc1F,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05277709,CC(=O)CCC(=O)O.Cc1ccc(C=O)cc1>>Cc1ccc(C=CC(=O)CCC(=O)O)cc1,,CCO,,Cl,[Na+].[OH-],test
US05130335,Cc1cc2c(cc1C(=O)Oc1ccc(C(=O)OCc3ccccc3)cc1)C(C)(C)CCC2(C)C>>Cc1cc2c(cc1C(=O)Oc1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C,[Pd],CCOC(C)=O,,,,test
US20090082330A1,CNCCNC.COC(=O)C(Br)c1ccc([N+](=O)[O-])cc1>>CN1CCN(C)C(c2ccc([N+](=O)[O-])cc2)C1=O,,CCO,,,,test
US05246948,CC1(C)NC(=O)N(CCCCSc2ccncc2)C1=O.ClCCCCSc1ccncc1>>CC1(C)C(=O)N(CCCCSc2ccncc2)C(=O)N1CCCCSc1ccncc1,,CN(C)C=O,,O,[H-].[Na+],test
US20040058971A1,CC(=O)C1(NS(=O)(=O)Cc2ccc(Cl)cc2)CCCCC1>>CC1=C(c2ccc(Cl)cc2)SNC12CCCCC2,,CN(C)C=O,,O,[H-].[Na+],test
US20160237081A1,CI.N#CCc1ccc(F)cc1>>CC(C#N)c1ccc(F)cc1,,C1CCOC1,,CC(C)(C)O,CC(C)(C)[O-].[K+],test
US20060004052A1,Cc1ccc(-c2[nH]c3cc(NC(=O)[C@@H](CCc4ccccc4)NC(=O)OC(C)(C)C)cc4c3c2C=NNC4=O)cn1>>Cc1ccc(-c2[nH]c3cc(NC(=O)[C@H](N)CCc4ccccc4)cc4c3c2C=NNC4=O)cn1,,Cl,,,,test
US05084572,C1NCC2CSCC1C2.O=C(Cl)c1ccccc1>>O=C(c1ccccc1)N1CC2CSCC(C2)C1,,ClCCl,O,CCOC(C)=O,[Na+].[OH-],test
US20100216844A1,N=C1c2ncccc2C(=O)N1CC(=O)c1ccccc1>>O=C(O)c1cccnc1-c1ncc(-c2ccccc2)[nH]1,,O,,Cl,[Na+].[OH-],test
US20040044052A1,COC(=O)C1CN(c2ccc3c(c2)CCC(=O)N3C)C(=O)O1.N>>CN1C(=O)CCc2cc(N3C[C@H](C(N)=O)OC3=O)ccc21,,CO,,,,test
US04279918,COc1ccc(CC2CCCN2Cc2ccccc2)cc1OC>>COc1ccc(CC2CCCN2)cc1OC,[Pd],CCO,,[H][H],,test
US20020016329A1,COC(=O)c1cccc(N)c1.Clc1nc(Cl)c2[nH]cnc2n1>>COC(=O)c1cccc(Nc2nc(Cl)nc3[nH]cnc23)c1,,CCCCCO,,CC(C)O,,test
US20160229847A1,CS(=O)(=O)OCc1cccc(Br)c1.NCCO>>OCCNCc1cccc(Br)c1,,CC(C)O,,,,test
US04686220,CC12OC1C(=O)c1ccccc1C2=O.CCOC(=O)N1CCNCC1>>CCOC(=O)N1CCN(C2=C(C)C(=O)c3ccccc3C2=O)CC1,,CCO,,,,test
US20080039506A1,CC(=O)OCCCS(=O)(=O)NC(=O)c1ccc(-c2ccc(CCCN(C[C@H](O)c3cccnc3)C(=O)OC(C)(C)C)cc2)cc1OCC(C)C>>CC(C)COc1cc(-c2ccc(CCCN(C[C@H](O)c3cccnc3)C(=O)OC(C)(C)C)cc2)ccc1C(=O)NS(=O)(=O)CCCO,,C1CCOC1,CO,[Na+].[OH-],,test
US04904674,O=C(O)c1ccc(C=Cc2cc3ccccc3s2)s1.O=S(Cl)Cl>>O=C(Cl)c1ccc(C=Cc2cc3ccccc3s2)s1,,ClCCl,,,,test
US03971789,Clc1ccc2c(Cl)ccnc2c1.Nc1cc(Cl)ccc1C(=O)O>>O=C(O)c1ccc(Cl)cc1Nc1ccnc2cc(Cl)ccc12,,Cl,,,,test
US20130225589A1,CCN(C(C)C)C(C)C.CN1CCN(c2ccc(N)cc2)CC1.CSc1ncc2c(=O)n(-c3ccccc3Cl)c3ccccc3c2n1.O=C(OO)c1cccc(Cl)c1>>CC(=O)[O-].CN1CCN(c2ccc(Nc3ncc4c(=O)n(-c5ccccc5Cl)c5ccccc5c4n3)cc2)CC1.[NH4+],,Cc1ccccc1,,,,test
US20110190490A1,CCCOc1nc(CN2CCOCC2)nc2oc(-c3cccc(OC)c3)nc12>>CCCOc1nc(CN2CCOCC2)nc2oc(-c3cccc(O)c3)nc12,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20060111375A1,COc1cc2c(Oc3cc4ccccc4nc3C)ccnc2cc1OCCCl.c1c[nH]cn1>>COc1cc2c(Oc3cc4ccccc4nc3C)ccnc2cc1OCCn1ccnc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20040186147A1,CCOC(=O)C1(Cc2ccccc2CBr)CCCC1=O>>CCOC(=O)C12CCC(Cc3ccccc3C1)C2=O,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20110301161A1,CC(C)(C)n1c(-c2cc(O)ccc2-n2cncn2)nc2cc(-c3cnc(N)nc3)ccc21.CCI>>CCOc1ccc(-n2cncn2)c(-c2nc3cc(-c4cnc(N)nc4)ccc3n2C(C)(C)C)c1,,CC#N,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20100280030A1,CC(=O)O.N=C(NO)c1cccc(C(=O)O)c1>>Cc1nc(-c2cccc(C(=O)O)c2)no1,,CC(=O)O,,CC(=O)OC(C)=O,,test
US07999132B2,COc1cccc(/C=C/c2ccc(C(=O)OC(C)(C)C)c(N)c2)c1.O=C(Cl)c1ccc(F)cc1>>COc1cccc(/C=C/c2ccc(C(=O)OC(C)(C)C)c(NC(=O)c3ccc(F)cc3)c2)c1,,CCN(CC)CC,ClCCl,O=C([O-])O.[Na+],,test
US20140148412A1,C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@](C)(O)CC[C@@]43C)[C@@H]1CC[C@@H]2C=O.NO>>C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@](C)(O)CC[C@@]43C)[C@@H]1CC[C@@H]2C=NO,,CCO,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US06087380,CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)N)cc1)n2C)c1ccccc1.COC(=O)Cl>>CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)NC(=O)OC)cc1)n2C)c1ccccc1,,CCO,ClCCl,Cl,,test
US20080132496A1,N#Cc1ccc(C(=O)CBr)cc1.NC1=NCCS1>>N#Cc1ccc(-c2cnc3n2CCS3)cc1,,CC#N,CO,Cl,N,test
US20150023878A1,CCCC[Sn](CCCC)(CCCC)c1ccc2c(c1)Cc1cc(N)ccc1-2.COC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1>>CCCC[Sn](CCCC)(CCCC)c1ccc2c(c1)Cc1cc(NC(=O)C[C@H](NC(=O)OCc3ccccc3)C(=O)OC)ccc1-2,,ClCCl,O,,,test
US20100234415A1,CCCOC(=O)Cc1c2n(c3ccccc13)CC(n1cc(Cc3ccccc3)nn1)CC2>>O=C(O)Cc1c2n(c3ccccc13)CC(n1cc(Cc3ccccc3)nn1)CC2,,C1CCOC1,CO,[K+].[OH-],,test
US04829063,CC(Cc1ccc2ccccc2c1)CS(C)(=O)=O.CC1CNCC(C)O1>>CC(Cc1ccc2ccccc2c1)CN1CC(C)OC(C)C1,,O,,,,test
US20110105562A1,O=C1c2ccccc2C(=O)N1CCCC#Cc1cccc(Br)c1.OB(O)c1ccccc1>>O=C1c2ccccc2C(=O)N1CCCC#Cc1cccc(-c2ccccc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,,,test
US20050032871A1,Cc1[nH]c(C=O)c(CCC(=O)N(C)C)c1S(=O)(=O)c1cccc(C(=O)O)c1.O=C1Cc2cc(F)ccc2N1>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(CCC(=O)N(C)C)c1S(=O)(=O)c1cccc(C(=O)O)c1,,CCO,,C1CCNCC1,,test
US20090291974A1,COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(-c2ncccn2)nc1OCCO.Cc1ccccc1S(=O)(=O)O>>COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(-c2ncccn2)nc1OCCO.Cc1ccc(S(=O)(=O)O)cc1,,CC#N,,O,,test
US20100331315A1,O=C1CSC(=S)N1.O=Cc1ccc(-c2ccc(Cl)c(C(=O)O)c2)o1>>O=C1NC(=S)SC1=Cc1ccc(-c2ccc(Cl)c(C(=O)O)c2)o1,,CCO,,C1CCNCC1,,test
US20150239889A1,O=C(Oc1ccc2c(c1Br)CCCC2)c1ccccc1.OB(O)C1CC1>>O=C(Oc1ccc2c(c1C1CC1)CCCC2)c1ccccc1,,C1COCCO1,,[Cs+].[F-],,test
US20040067955A1,CC(C)n1nc(-c2ccc(OCC(N)=O)nc2-c2ccccc2)ccc1=O.COOC(OOC)N(C)C.NN>>CC(C)n1nc(-c2ccc(OCc3ncn[nH]3)nc2-c2ccccc2)ccc1=O,,CC(=O)O,,O,O=C([O-])O.[Na+],test
US20030220373A1,N#CCOc1cccc(CCl)c1.[O-]c1ccc(OCc2ccc3ccccc3n2)cc1>>N#CCOc1cccc(COc2ccc(OCc3ccc4ccccc4n3)cc2)c1,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20070037888A1,CC(C)(C)OC(=O)NC1CCNCC1.Cc1cc(Nc2cc(Cl)nc(N3CCCC3c3cc(-c4ccccn4)no3)n2)n[nH]1>>Cc1cc(Nc2cc(N3CCC(NC(=O)OC(C)(C)C)CC3)nc(N3CCCC3c3cc(-c4ccccn4)no3)n2)n[nH]1,,C1COCCO1,,,,test
US04410529,NN.O=C(O)CCC(=O)c1ccc(NC(=O)C2CC2)cc1>>O=C1CCC(c2ccc(NC(=O)C3CC3)cc2)=NN1,,CCO,,O,,test
US06288091B1,CC(=O)c1ccc(N)cc1.CC(C)COC(=O)Cl>>CC(=O)c1ccc(NC(=O)OCC(C)C)cc1,,C1CCOC1,CCOC(C)=O,c1ccncc1,,test
US20160038504A1,Fc1ncc(Br)cc1N1CCOCC1.OCC(F)F>>FC(F)COc1ncc(Br)cc1N1CCOCC1,,C1COCCO1,,[H-].[Na+],,test
US06274632B1,FC(F)=CCCSc1nc2ccccc2s1.O=C(O)c1ccccc1C(=O)OO>>O=S(=O)(CCC=C(F)F)c1nc2ccccc2s1,,ClCCl,O,[Mg],,test
US20140094450A1,CNS(=O)(=O)C[C@H](CC(C)C)NC(=O)OC(C)(C)C.Cl>>CNS(=O)(=O)C[C@@H](N)CC(C)C.Cl,,C1COCCO1,,,,test
US03993604,C=C(C)C1CC=C(CO)CC1>>CC(C)C1CCC(CO)CC1,[Ni],CCO,,,,test
US20100310512A1,O=c1oc2cc(Br)ccc2c2ccc(Br)cc12>>Brc1ccc2c(c1)COc1cc(Br)ccc1-2,,C1CCOC1,,[BH4-].[Li+],,test
US20130217671A1,CC(=O)c1cnc2ccc(Br)cc2c1N[C@@H]1CC[C@@H](COS(C)(=O)=O)CC1.CC(C)(C)OC(=O)N1CCNCC1>>CC(=O)c1cnc2ccc(Br)cc2c1N[C@@H]1CC[C@@H](CN2CCN(C(=O)OC(C)(C)C)CC2)CC1,,C1COCCO1,CC#N,CCN(C(C)C)C(C)C,,test
US20130012528A1,C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1.ClCCl>>C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)c(Cl)c23)c1,,CC#N,,N#N,,test
US20110143149A1,CCOC(C)=O.COS(=O)(=O)C(F)(F)F.CO[Si](CCCN(C)C)(OC)OC>>CO[Si](CCC[N+](C)(C)C)(OC)OC.O=S(=O)([O-])C(F)(F)F,,CCOC(C)=O,,,,test
US06051718,O=Cc1ccc(OC(F)F)c(OC2CCOC2)c1>>OCc1ccc(OC(F)F)c(OC2CCOC2)c1,,CO,,[BH4-].[Na+],,test
US05629409,Nc1c(N=Nc2cc(S(=O)(=O)O)ccc2S(=O)(=O)O)c(S(=O)(=O)O)cc2cc(S(=O)(=O)O)cc(O)c12>>Nc1cc(S(=O)(=O)O)cc2cc(S(=O)(=O)O)cc(O)c12.Nc1cc(S(=O)(=O)O)ccc1S(=O)(=O)O,,O,,[Na],,test
US20090275617A1,CCOC(=O)C(CC(C)=O)C(=O)CC.Nc1cc(F)cc(F)c1>>CCOC(=O)c1cc(C)n(-c2cc(F)cc(F)c2)c1CC,,CC(=O)O,,,,test
US20120264735A1,CCOc1cnc(-c2cccc(C(=O)c3nn(-c4cnn(C)c4)ccc3=O)c2)nc1>>CCOc1cnc(-c2cccc(C(O)c3nn(-c4cnn(C)c4)ccc3=O)c2)nc1,,CO,,[BH4-].[Na+],[Cl-].[NH4+],test
US20050176751A1,CCOC(=O)N1CCC(c2cn(C(=O)OCC)c3ncccc23)CC1>>c1cnc2[nH]cc(N3CCCCC3)c2c1,,CC(C)O,,[K+].[OH-],,test
US20090247559A1,Cc1cc(Br)cc2c1oc1c(=O)[nH]c(CCl)nc12.O[C@H]1CCNC1>>Cc1cc(Br)cc2c1oc1c(=O)[nH]c(CN3CC[C@H](O)C3)nc12,,CCO,,CCN(CC)CC,,test
US20060084680A1,CCOC(=O)C[C@@H]1CCc2cc(OCCCOc3ccc4c(C)coc4c3)ccc21>>Cc1coc2cc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)ccc12,,C1CCOC1,O,[Li]O,,test
US20120329780A1,CN1CCN(C(=O)c2ccc(N)cc2)CC1.COc1ccc(Cn2cc3nc(-c4ccsc4)nc(Cl)c3n2)cc1>>CN1CCN(C(=O)c2ccc(Nc3nc(-c4ccsc4)nc4cn[nH]c34)cc2)CC1,C1COCCO1,CO,,Cl,,test
US20070004753A1,CC(C)=O.Cc1ccc(N)cc1.[C-]#N>>Cc1ccc(NC(C)(C)C#N)cc1,,CC(=O)O,,CCOC(C)=O,,test
US04710499,COCCN.Cc1cc(-c2ccccc2)nnc1Cl>>COCCNc1nnc(-c2ccccc2)cc1C,,CCCCO,,O,,test
US20110130384A1,O=C1CC(c2ccc(Cl)cc2Cl)c2cc(Br)ccc2O1>>OCCC(c1cc(Br)ccc1O)c1ccc(Cl)cc1Cl,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050234109A1,CC(C)(C)[Si](OC/C=C\CC(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1>>O=S(=O)(c1ccc(Cl)cc1)C(C/C=C\CO)c1cc(F)ccc1F,,C1CCOC1,CCCCCC,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20120322784A1,CC(=O)Nc1ccc(I)cn1.CC(C)OC(=O)N1CCC(C2Cc3cc(B4OC(C)(C)C(C)(C)O4)ccc3O2)CC1>>CC(=O)Nc1ccc(-c2ccc3c(c2)CC(C2CCN(C(=O)OC(C)C)CC2)O3)cn1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20020115863A1,CCCCC(C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C)C1OC(C)(C)OC1=O.CO>>CCCC[C@@H](C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C)[C@H](O)C(=O)OC,,CO,,C[O-].[Na+],,test
US20030120080A1,CC[C@@H](C(=O)OC(C)(C)C)N1CC(CO)CC1=O>>CC[C@@H](C(=O)OC(C)(C)C)N1CC(C=O)CC1=O,,ClCCl,c1ccncc1,,,test
US20080119457A1,CNN.COC1=CC(C)(C)CC(C(=O)c2ccc(C#N)c(Br)c2)C1=O>>Cn1nc(-c2ccc(C#N)c(Br)c2)c2c1C(=O)CC(C)(C)C2,CC(=O)O,C1CCOC1,CO,Cl,O=C([O-])O.[Na+],test
US20120088763A1,CCOC(=O)CC1CCC(Oc2ccc3nnc(C(C)C)n3c2)CC1>>CC(C)c1nnc2ccc(OC3CCC(CC(=O)O)CC3)cn12,,CO,,Cl,[Na+].[OH-],test
US04666923,CC(=O)Nc1ccc2c(c1)NC(=O)C2.CC(C)C=O>>CC(=O)Nc1ccc2c(c1)NC(=O)C2=C(C)C,,CCO,,O,[Na+].[OH-],test
US20080045549A1,CCOC(=O)c1cc(C)[nH]n1.O=C(CBr)Nc1ccccc1>>CCOC(=O)c1nn(C(=O)Nc2ccccc2)c(C)c1C,,CCO,,C,C[O-].[Na+],test
US05206375,CCOc1csc(N)c1C#N>>N#Cc1c(O)csc1N,,O,,CO,Cl,test
US20040002503A1,CI.O=C(Nc1cccc(F)c1)c1cccc(I)c1>>CN(C(=O)c1cccc(I)c1)c1cccc(F)c1,,CN(C)C=O,,[H-].[Na+],,test
US20100261698A1,CCC(=O)c1cccnc1.Cl.NNc1ccccc1>>Cc1c(-c2cccnc2)[nH]c2ccccc12.Cl,,CCO,,Cl,,test
US06030975,COc1cc(OC)nc(OC(C(=O)O)C(SC)(c2ccccc2)c2ccccc2)n1.OO>>COc1cc(OC)nc(OC(C(=O)O)C(c2ccccc2)(c2ccccc2)S(C)=O)n1,,O,,CC(=O)O,,test
US20100137586A1,COc1cc2nc[nH]c(=O)c2cc1OCCCCl.O=S(Cl)Cl>>COc1cc2ncnc(Cl)c2cc1OCCCCl,,CN(C)C=O,,,,test
US20050256171A1,O=S(Cl)Cl.OCc1cc(Br)cc(Br)c1>>ClCc1cc(Br)cc(Br)c1,,CN(C)C=O,,,,test
US20140309227A1,COC(=O)c1cc(Br)c2cccc(F)c2n1.OB(O)c1ccc(F)cc1>>O=C(O)c1cc(-c2ccc(F)cc2)c2cccc(F)c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20160221972A1,COC(=O)c1ccc(CNCCO)c(Br)c1>>COC(=O)c1ccc2c(c1)OCCNC2,[Cu]I,CC(C)O,,O=C([O-])[O-].[K+].[K+],,test
US20030166650A1,CC(N=[N+]=[N-])c1ccc(F)c(N2CCOCC2)c1>>CC(N)c1ccc(F)c(N2CCOCC2)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080153812A1,CCOC(=O)c1ccc(N2C[C@H](C)N(C)[C@H](C)C2)cc1.COc1cc(CCc2cc(N)[nH]n2)cc(OC)c1>>COc1cc(CCc2cc(NC(=O)c3ccc(N4C[C@H](C)N(C)[C@H](C)C4)cc3)[nH]n2)cc(OC)c1,,Cc1ccccc1,,C[Al](C)C,,test
US20040044008A1,N#Cc1cccc(CBr)c1.O=C(Nc1cccc(N2CCNCC2)c1)c1ccccc1-c1ccc(C(F)(F)F)cc1>>N#Cc1cccc(CN2CCN(c3cccc(NC(=O)c4ccccc4-c4ccc(C(F)(F)F)cc4)c3)CC2)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04216160,CC(=O)NC(=O)CCl.CCC(O)=S>>CCC(=O)SCC(=O)NC(C)=O,,O,,[Na+].[OH-],,test
US20070032531A1,CCCCCCCCCCCCCC(=O)Cl.Nc1nc2cc(Cl)ccc2o1>>CCCCCCCCCCCCCC(=O)Nc1nc2cc(Cl)ccc2o1,,c1ccccc1,,,,test
US20120220563A1,CC(F)(F)c1ccc(C2CC(C(=O)O)CN(C(=O)N3CCSCC3)C2)cc1.CCOC(=N)NO>>CCOc1noc(C2CC(c3ccc(C(C)(F)F)cc3)CN(C(=O)N3CCSCC3)C2)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090298878A1,Fc1ccc(C(CCCN2CCC3(CC2)OCCO3)c2ccc(F)cc2)cc1>>OC1(O)CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1,,C1CCOC1,,,,test
US05051427,CS(=O)(=O)Cl.OCc1cccc(Cc2ccc(OCc3ccc4ccccc4n3)cc2)c1>>CS(=O)(=O)OCc1cccc(Cc2ccc(OCc3ccc4ccccc4n3)cc2)c1,,ClCCl,,CCN(CC)CC,,test
US20110046169A1,Nc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3c2)cc1.O=C(O)C1(C(=O)Nc2ccc(F)cc2)CC1>>O=C(Nc1cn2cc(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3)ccc2n1)C1CC1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090054665A1,CC1=CC(=O)OC(C)(C)O1.COC(=O)C(NC(=O)OC(C)(C)C)P(=O)(OC)OC>>COC(=O)C1C(C)=CC(=O)N1C(=O)OC(C)(C)C,,Cc1ccccc1,,Cc1cccc(C)n1,,test
US20120157430A1,CC(=O)c1cc(Cl)c(F)c(-c2cncc(S(C)(=O)=O)c2)c1O.CCO>>CCOc1c(C(C)=O)cc(Cl)c(F)c1-c1cncc(S(C)(=O)=O)c1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070149570A1,CC(C)(C)OC(=O)N1CC[C@H](N)[C@H](c2ccc(F)cc2)C1.COc1ccc(-c2ccc(C#N)cc2)cc1C=O>>COc1ccc(-c2ccc(C#N)cc2)cc1CN[C@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1c1ccc(F)cc1,,CC(=O)O,ClCCl,O=C([O-])O.[Na+],,test
US20140066390A1,CCCCCCCCCCCCCC(=O)Cl.CCCCCCCCCCCCCC(=O)O[C@H]1[C@H](OCc2ccc(OC)cc2)[C@@H](CO)O[C@H](OC)[C@@H]1O.O=C1CCC(=O)O1>>CCCCCCCCCCCCCC(=O)O[C@H]1[C@H](OCc2ccc(OC)cc2)[C@@H](COC(=O)CCC(=O)O)O[C@H](OC)[C@@H]1OC(=O)CCCCCCCCCCCCC,CN(C)c1ccncc1,c1ccncc1,,,,test
US20110015225A1,C=COC(C)=O.COC(=O)c1ccc(CO)cc1>>C=COCc1ccc(C(=O)OC)cc1,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20050049203A1,CC(=O)OC[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.COc1ccc(Cc2c(C)nc(C)[nH]c2=O)cc1>>COc1ccc(Cc2c(C)nc(C)nc2O[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140113935A1,CNCc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.Cc1ccc(N=C=O)cc1Cl>>Cc1ccc(NC(=O)N(C)Cc2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)cc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US06174901B1,CC(=O)OC1(c2cccc(C)c2)CNC(=O)C=C1c1ccncc1>>Cc1cccc(C2(O)CNC(=O)C=C2c2ccncc2)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20100174065A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCN(CCC(=O)OC(C)(C)C)CC4)no2)cc1Cl.Cl>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCN(CCC(=O)O)CC4)no2)cc1Cl.Cl,,C1COCCO1,Cl,,,test
US03976786,Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1.O=CO>>O=CNc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1,,O,,CC(=O)OC(C)=O,,test
US20100137281A1,CCOC(=O)c1c(N)sc(OC)c1C.C[C@H](N)c1ccccc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1sc2[nH]c(=O)n([C@@H](C)c3ccccc3)c(=O)c2c1C,,ClCCl,,CCN(CC)CC,,test
US06124493,COC(=O)C(=O)c1ccccc1CN(C)C.COC(=O)Cl>>COC(=O)C(=O)c1ccccc1CCl,,Cc1ccccc1,,,,test
US20100137308A1,COC(=O)c1ccc(OC)cc1Nc1nc2ccccc2nc1NS(=O)(=O)c1cccnc1>>COc1ccc(C(=O)O)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cccnc2)c1,,CO,,O,O=C([O-])[O-].[K+].[K+],test
US20030130506A1,ClCCCl.O=S(=O)(O)Cl.c1ccc(Oc2ccncc2)cc1>>Cl.O=S(=O)(Cl)c1ccc(Oc2ccncc2)cc1,,ClCCCl,,,,test
US20140045862A1,COc1ccc(CN(c2nncs2)S(=O)(=O)c2cc(Cl)c(O[C@H]3CCC[C@@H]3c3ccnn3C)cc2F)c(OC)c1>>Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2nncs2)cc1Cl,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US07244747B2,COc1ccc(CN2CC(CO)CC2=O)cc1>>COc1ccc(CN2CC(C=O)CC2=O)cc1,,ClCCl,,CCN(CC)CC,,test
US20070032485A1,CCOC(=O)N1c2ccc(OC)nc2[C@@H](N)C[C@H]1CC.COc1cc(OC)nc(Cl)n1>>CCOC(=O)N1c2ccc(OC)nc2[C@@H](Nc2nc(OC)cc(OC)n2)C[C@H]1CC,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US05914339,CC(OC(=O)C1(C(=O)OC(C)c2ccccc2)Oc2ccc(C[C@@H](C)NC[C@H](O)c3cccc(Cl)c3)cc2O1)c1ccccc1>>CC(OC(=O)C1(C(=O)O)Oc2ccc(C[C@@H](C)NC[C@H](O)c3cccc(Cl)c3)cc2O1)c1ccccc1,,CO,ClC(Cl)Cl,,,test
US04259338,CCOC(=O)c1ccc(OC(C)C(C)=O)c(OC)c1>>CCOC(=O)c1cc(OC)c2oc(C)c(C)c2c1,,O=S(=O)(O)O,,,,test
US20010041710A1,CC(C)(C)OC(=O)[C@H]1CN(Cc2ccc(Oc3ccc(F)cc3)cc2)C(=O)N1>>O=C(O)[C@H]1CN(Cc2ccc(Oc3ccc(F)cc3)cc2)C(=O)N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US08952009B2,COC(=O)c1ccc(Br)cc1C.COC(=O)c1ccc(C#N)cc1C.N#C[Cu]>>O=C(O)c1ccc2c(c1)CNC2=O,,CCOC(C)=O,CN(C)C=O,,,test
US20140121367A1,CC(=O)Nc1ccc(OC(=O)c2cccnc2)cc1.CC(C)N(C(=O)OCI)C(C)C>>CC(=O)Nc1ccc(OC(=O)c2ccc[n+](COC(=O)N(C(C)C)C(C)C)c2)cc1.[I-],,CC#N,,,,test
US20100009985A1,COC(=O)Cl.C[C@@]1(c2ccccc2)CCN2CC[C@@](C)(c3ccccc3)c3cc([N+](=O)[O-])cc1c32>>COC(=O)Nc1cc2c3c(c1)[C@](C)(c1ccccc1)CCN3CC[C@@]2(C)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20040067960A1,Nc1ccccc1CCN1CCN(c2nsc3ccccc23)CC1.O=C(Cl)CCCl>>NC(=O)C(CCl)c1ccccc1CCN1CCN(c2nsc3ccccc23)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20060287341A1,Cc1ccc(C=O)cn1.NO>>Cc1ccc(C=NO)cn1,,CO,,,,test
US20080044379A1,CI.CN1CCNC1=S>>CSC1=NCCN1C.I,,CC(C)=O,,,,test
US20130143914A1,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1.N[C@H]1CC[C@H](Oc2ccc3nnc(-c4ccccc4SCCOC4CCCCO4)n3c2)c2ccccc21>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@H](Oc3ccc4nnc(-c5ccccc5SCCOC5CCCCO5)n4c3)c3ccccc32)cc1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US07157487B2,COC(=O)c1ccc(OC[C@@H]2C[C@H](Oc3ccc4ccccc4c3)CN2C(=O)Cc2ccc3nc(Nc4ccccc4C)oc3c2)cc1>>Cc1ccccc1Nc1nc2ccc(CC(=O)N3C[C@@H](Oc4ccc5ccccc5c4)C[C@H]3COc3ccc(C(=O)O)cc3)cc2o1,,C1CCOC1,,[Na+].[OH-],,test
US20060154974A1,O=C(Nc1nccs1)c1ccc([N+](=O)[O-])cc1-c1ccccc1>>Nc1ccc(C(=O)Nc2nccs2)c(-c2ccccc2)c1,[Zn],CO,,CC(=O)O,,test
US20070117854A1,FC(F)(F)C(F)(F)c1ccn(CCl)n1.N#CC(C#N)CCC(F)(F)F>>N#CC(C#N)(CCC(F)(F)F)Cn1ccc(C(F)(F)C(F)(F)F)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04468394,CC(=O)Oc1cc2cc(C(=O)O)c(=O)[nH]c2cc1OC(C)=O.O=S(Cl)Cl>>CC(=O)Oc1cc2cc(C(=O)Cl)c(=O)[nH]c2cc1OC(C)=O,CN(C)C=O,c1ccccc1,,,,test
US20160002255A1,COC(=O)[C@@H](C)[C@H](c1ccc(CC[C@@H](O)c2ccc(-c3cc(OC)ccc3F)cc2)c(O)c1)C1CC1>>COC(=O)[C@@H](C)[C@H](c1ccc2c(c1)O[C@H](c1ccc(-c3cc(OC)ccc3F)cc1)CC2)C1CC1,,ClCCl,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070191603A1,BrCBr.COC(=O)c1ccc(O)c(NS(=O)(=O)c2cc(Cl)ccc2OC)c1>>COC(=O)c1ccc2c(c1)N(S(=O)(=O)c1cc(Cl)ccc1OC)CO2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160207926A1,NO.O=C1CCCC(N(Cc2ccccc2)Cc2ccccc2)C1>>ON=C1CCCC(N(Cc2ccccc2)Cc2ccccc2)C1,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20130130997A1,CCOc1ccc(C(O)c2cc(Br)ccc2Cl)cc1F>>CCOc1ccc(Cc2cc(Br)ccc2Cl)cc1F,,ClCCl,,CCOCC,FB(F)F,test
US06229055B1,NC=CCc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O>>O=c1ccn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1,,CN(C)C=O,O,CCN(CC)CC,,test
US20090270350A1,CN.Cc1ccc(C(=O)O)cc1-n1c(C)cc(OCc2ccccc2CNC(=O)Nc2cc(C(C)(C)C)nn2-c2cccc(OCCO)c2)c(Cl)c1=O>>CNC(=O)c1ccc(C)c(-n2c(C)cc(OCc3ccccc3CNC(=O)Nc3cc(C(C)(C)C)nn3-c3cccc(OCCO)c3)c(Cl)c2=O)c1,,CCOC(C)=O,,,,test
US20140179680A1,C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3C(F)(F)F)nc3cc(C(N)=NO)nc(-c4cncc(Cl)c4)c32)CC1.O=C(n1ccnc1)n1ccnc1>>C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3C(F)(F)F)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20110319378A1,CCC(=O)c1cccnc1>>CCC(O)c1cccnc1,,CO,,O,[BH4-].[Na+],test
US20120316170A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.COCn1cnc(CO)c1>>COCn1cnc(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20050245592A1,CC(=O)Cl.COCOc1c(N)cc(C(C)=O)cc1C(C)(C)C>>COCOc1c(NC(C)=O)cc(C(C)=O)cc1C(C)(C)C,,C1CCOC1,,CCN(CC)CC,,test
US20060111362A1,CC(C)(C)OC(=O)N1CCNCC1.O=[N+]([O-])c1c(Cl)ncnc1Cl>>CC(C)(C)OC(=O)N1CCN(c2ncnc(Cl)c2[N+](=O)[O-])CC1,,CC#N,,CCN(CC)CC,O,test
US20150322076A1,CC(C)(C#N)C[C@@H]1N[C@@H](C(=O)OC(C)(C)C)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12>>CC(C)(C#N)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12,,C1CCOC1,ClCCl,,,test
US05486466,C=CCc1c(O)cc(O)c(C)c1C(=O)OC>>CCCc1c(O)cc(O)c(C)c1C(=O)OC,[Pd],CCOC(C)=O,,,,test
US20110212937A1,COc1cc(N)ccc1-n1cnc(Cl)n1.Fc1ccc(C2CCc3c2nc(Cl)nc3N2CC(F)(F)C2)cc1>>COc1cc(Nc2nc3c(c(N4CC(F)(F)C4)n2)CCC3c2ccc(F)cc2)ccc1-n1cnc(Cl)n1,,C1CCOC1,CO,CC(=O)O,,test
US20120309735A1,CCOC(=O)C1CCN(c2ncc(-c3cccc([N+](=O)[O-])c3)s2)CC1>>CCOC(=O)C1CCN(c2ncc(-c3cccc(N)c3)s2)CC1,[Pd],CC(=O)O,CCOC(C)=O,,,test
US20050176745A1,BrBr.c1cc(-c2cnc3c(c2)C[C@@]2(CN4CCC2CC4)O3)co1>>Brc1occc1-c1cnc2c(c1)C[C@@]1(CN3CCC1CC3)O2,,CN(C)C=O,ClC(Cl)Cl,,,test
US20040254217A1,CC(=O)C(Cl)Cl.NC(=O)C=Cc1ccc(SC(F)(F)F)cc1>>FC(F)(F)Sc1ccc(C=Cc2nc(CCl)co2)cc1,,Cc1ccccc1,,,,test
US20110124634A1,CCOC(=O)c1ncc(C(=O)N2CCC(O[Si](C)(C)C(C)(C)C)CC2)[nH]1>>CC(C)(C)[Si](C)(C)OC1CCN(C(=O)c2cnc(C=O)[nH]2)CC1,O=[Mn]=O,ClCCl,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070037807A1,Cc1ccc(-c2c(CNC(=O)OC(C)(C)C)c(CC(C)C)nc(C)c2C(=O)OCC#N)cc1.S>>Cc1ccc(-c2c(CNC(=O)OC(C)(C)C)c(CC(C)C)nc(C)c2C(=O)OCC(N)=S)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20080275037A1,Cc1ncc(C(C)O)cn1.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>Cc1ncc(C(C)N=[N+]=[N-])cn1,,CCOC(C)=O,Cc1ccccc1,C1CCC2=NCCCN2CC1,,test
US20090099199A1,Nc1cc(F)c(F)cc1[N+](=O)[O-].c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>Nc1cc(N2CCN(C(c3ccccc3)c3ccccc3)CC2)c(F)cc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090312241A1,CC(=O)O[BH-](OC(C)=O)OC(C)=O.COC(=O)[C@@H]([NH3+])C(C)(C)C.ClCCCl.ClCCl>>C=CCCCCN[C@H](C(=O)OC)C(C)(C)C,,ClCCCl,ClCCl,[Cl-].[Na+],,test
US20140163219A1,CC(C)c1ncc(C=O)s1.COc1ccc2oc(C(C)=O)c(N)c2c1Cl>>COc1ccc2oc(C(=O)/C=C/c3cnc(C(C)C)s3)c(N)c2c1Cl,,C1CCOC1,,[Na+].[OH-],,test
US06835714B1,CCOC(=O)C(O)[C@H](CC)NC(=O)OCc1ccccc1.NCc1ccccc1>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(O)C(=O)NCc1ccccc1,,O,,C1CCOC1,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20080058356A1,Clc1cc(-n2cccn2)nc(-c2ccco2)n1.NCC1CC1>>c1coc(-c2nc(NCC3CC3)cc(-n3cccn3)n2)c1,,CCCCCO,,,,test
US20090124698A1,C#CC(=O)OCC.COCOc1ccc(I)cc1>>CCOC(=O)C#Cc1ccc(OCOC)cc1,O=[Cu-],CN(C)C=O,,O,,test
US04748240,CC1(C)C2CCC1C(=O)OC2=O.NCCCCN1CCN(c2cncc(Cl)n2)CC1>>CC1(C)C2CCC1C(=O)N(CCCCN1CCN(c3cncc(Cl)n3)CC1)C2=O,,O,,Cc1ccccc1C,,test
US04421757,CC(=O)Oc1ccc(N=c2scc(-c3ccc(Cl)c(S(=O)(=O)N(C)C)c3)n2C)cc1>>CN(C)S(=O)(=O)c1cc(-c2csc(=Nc3ccc(O)cc3)n2C)ccc1Cl,,CCO,O,Cl,[Na+].[OH-],test
US20100280268A1,COC(=O)c1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C)c2)ccc1NS(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)Nc2ccc(Oc3ccc(NS(=O)(=O)c4ccc(C)cc4)c(C(=O)O)c3)cc2C)cc1,,C1CCOC1,,Cl,[Li+].[OH-],test
US20070049593A1,COC(=O)c1ccc(N)c(NC(=O)C(C)(C)NC(=O)c2ccc3c(C4CCCCC4)c4n(c3c2)CCOc2cc(OC)ccc2-4)c1>>COC(=O)c1ccc2nc(C(C)(C)NC(=O)c3ccc4c(C5CCCCC5)c5n(c4c3)CCOc3cc(OC)ccc3-5)[nH]c2c1,,CC(=O)O,,Cc1ccccc1,,test
US20120202785A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)Nc1ncccc1Nc1ccccc1>>C[C@H](NC(=O)OC(C)(C)C)c1nc2ncccc2n1-c1ccccc1,,CC(=O)O,,,,test
US20120149721A1,C[C@H]1C[C@H](OCc2ccccc2)C[C@H]1OC(=O)c1cccc([N+](=O)[O-])c1>>C[C@H]1C[C@H](OCc2ccccc2)C[C@H]1O,,C1CCOC1,O,CO,,test
US20130045948A1,O=C=Nc1ccccc1.c1ccc(C2CC(c3csc(C4CCNCC4)n3)=NO2)cc1>>O=C(Nc1ccccc1)N1CCC(c2nc(C3=NOC(c4ccccc4)C3)cs2)CC1,,ClCCl,,CCOCC,,test
US20110077240A1,COCCN(Cc1cnc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)n1C)C(=O)OC(C)(C)C.O=C=Nc1ccc(F)cc1F>>COCCN(Cc1cnc(-c2cc3nccc(Oc4ccc(NC(=O)Nc5ccc(F)cc5F)cc4F)c3s2)n1C)C(=O)OC(C)(C)C,,ClCCl,,,,test
US20090203676A1,CSc1ccc(N)cc1F.ClCCNCCCl>>CSc1ccc(N2CCNCC2)cc1F,,Clc1ccccc1,,,,test
US20130040983A1,BrBr.c1ccc(-c2nc(-c3ccncc3)c[nH]2)cc1>>Brc1[nH]c(-c2ccccc2)nc1-c1ccncc1,,ClCCl,,c1ccncc1,,test
US20070249674A1,C=CC(=O)Nc1cc(C)c(C2OCCO2)cc1C.O=C(Nc1ccccc1-c1ccccc1)OC1CCNCC1>>Cc1cc(C2OCCO2)c(C)cc1NC(=O)CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1,,CCO,,ClCCl,,test
US20080015203A1,Cc1cnc(NC(=O)c2cc(O)cc(O[C@@H](C)CO)c2)cn1.O=C(c1ccc(F)c(F)c1)N1CCC1>>Cc1cnc(NC(=O)c2cc(Oc3ccc(C(=O)N4CCC4)cc3F)cc(O[C@@H](C)CO)c2)cn1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US06090802,CC(C)(C)OC(=O)N1CC[C@H](NC(=O)CCCNC(=NC(=O)OCc2ccc([N+](=O)[O-])cc2)NC(=O)OCc2ccc([N+](=O)[O-])cc2)C1.O=C(O)C(F)(F)F>>O=C(CCCNC(=NC(=O)OCc1ccc([N+](=O)[O-])cc1)NC(=O)OCc1ccc([N+](=O)[O-])cc1)NC1CNC1.O=C(O)C(F)(F)F,,ClCCCl,ClCCl,,,test
US04629494,CC(=O)OC(C)=O.COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(C)cc(CO)n1>>COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(C)cc(COC(C)=O)n1,,c1ccncc1,,,,test
US20150065507A1,COc1cccc(N(CC(C)C)S(=O)(=O)c2ccc(F)cc2)n1.OCc1ccncc1>>COc1cccc(N(CC(C)C)S(=O)(=O)c2ccc(OCc3ccncc3)cc2)n1,,CN(C)C=O,,[H-].[Na+],,test
US20160229853A1,Nc1ccc(Cl)cc1F.O=C1CSC1>>Fc1cc(Cl)ccc1NC1CSC1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20150299189A1,O=[N+]([O-])c1ccc2c(c1)CCCN2c1ccccc1>>Nc1ccc2c(c1)CCCN2c1ccccc1,[Pd],CO,,,,test
US20110201629A1,CC1(F)C(=O)Nc2cc(Cl)ccc21.Cc1ncc(Cl)cc1C(=O)N[C@@H]1CC[C@@H](COS(C)(=O)=O)CC1>>Cc1ncc(Cl)cc1C(=O)N[C@@H]1CC[C@@H](CN2C(=O)C(C)(F)c3ccc(Cl)cc32)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20160102105A1,Cc1cc(C#N)cnc1C(=O)O.O=C(Cl)C(=O)Cl>>Cc1cc(C#N)cnc1C(=O)Cl,,ClCCl,,CN(C)C=O,,test
US20150291563A1,O=C(O)CC(=O)O.O=Cc1cncc(Br)c1>>O=C(O)C=Cc1cncc(Br)c1,,c1ccncc1,,C1CCNCC1,,test
US20090270374A1,CCO/C=C/C(=O)Nc1cccc(OC)c1>>COc1ccc2ccc(=O)[nH]c2c1,,O=S(=O)(O)O,,,,test
US20050153959A1,Cc1cc(CC(CC(=O)OC(C)(C)C)c2ccccn2)cc2cn[nH]c12>>Cc1cc(CC(CC(=O)O)c2ccccn2)cc2cn[nH]c12,,C1COCCO1,,Cl,,test
US20070054916A1,Cc1c(N)cccc1B1OC(C)(C)C(C)(C)O1.O=C(Cl)c1cccc(C(F)(F)F)c1>>Cc1c(NC(=O)c2cccc(C(F)(F)F)c2)cccc1B1OC(C)(C)C(C)(C)O1,,ClCCl,,CCN(CC)CC,,test
US06166006,C=O.COCCN.O=Cc1ccc([N+](=O)[O-])cc1>>COCCN(C)Cc1ccc([N+](=O)[O-])cc1,,ClCCCl,,,,test
US04504491,C#C[Mg]Br.O=Cc1cccc(C(=O)c2ccccc2)c1>>C#CC(O)c1cccc(C(=O)c2ccccc2)c1,,C1CCOC1,,,,test
US20080280872A1,COC[C@H](C)Oc1cc(Oc2ccc(C(=O)OC)cc2Cl)cc(C(=O)Nc2ccn(C)n2)c1>>COC[C@H](C)Oc1cc(Oc2ccc(C(=O)O)cc2Cl)cc(C(=O)Nc2ccn(C)n2)c1,,C1CCOC1,O,[Li+].[OH-],,test
US03989507,CNS(=O)(=O)Cl.COC(=O)c1cccnc1N>>CNS(=O)(=O)Nc1ncccc1C(=O)OC,,CC#N,,O=C([O-])[O-].[Ca+2],,test
US20140243283A1,Brc1ccc2c(c1)C1(CCNCC1)c1cc(Br)ccc1-2.C=O>>CN1CCC2(CC1)c1cc(Br)ccc1-c1ccc(Br)cc12,,ClCCCl,,,,test
US20160272632A1,Cc1cc(Br)ccc1S(=O)(=O)Cl.O=C1CCC(=O)N1Br>>O=S(=O)(Cl)c1ccc(Br)cc1CBr,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20070105890A1,CCOC(=O)CN/C(=N\C#N)N1CCC[C@@H](NC(=O)OC(C)(C)C)C1.Fc1ccc(Cl)c(CBr)c1>>CCOC(=O)CN(Cc1cc(F)ccc1Cl)/C(=N/C#N)N1CCC[C@@H](NC(=O)OC(C)(C)C)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140099316A1,OCc1ccc(-c2noc(-c3ccc(-c4ccccc4)c(Cl)c3)n2)cc1>>O=Cc1ccc(-c2noc(-c3ccc(-c4ccccc4)c(Cl)c3)n2)cc1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20130143870A1,CC(O)CNC(=O)c1ccncc1>>CC(=O)CNC(=O)c1ccncc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04880812,CC(=O)Nc1nc(N(C(C)=O)C(C)=O)c(CCC=O)c(=O)[nH]1.CCOC(=O)c1ccc(N)cc1>>CCOC(=O)c1ccc(NCCCc2c(N(C(C)=O)C(C)=O)nc(NC(C)=O)[nH]c2=O)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20070082912A1,CCC(=O)CCC(=O)c1cc(Cl)ccc1OCc1ccccc1.CCOC(=O)c1cccc(N)c1>>CCOC(=O)c1cccc(-n2c(CC)ccc2-c2cc(Cl)ccc2OCc2ccccc2)c1,,CCOC(C)=O,Cc1ccccc1,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080293713A1,C#C[Mg]Br.CCOC(=O)C1CC1C=O>>C#CC(O)[C@@H]1C[C@H]1C(=O)OCC,,C1CCOC1,,,,test
US20130102776A1,CC(C)(C)OC(=O)N1CCNCC1.O=C1COc2c(CBr)cccc21>>CC(C)(C)OC(=O)N1CCN(Cc2cccc3c2OCC3=O)CC1,,ClCCl,,CC(=O)[O-].[Na+],,test
US20120245144A1,CON(C)C(=O)c1ccc2c(c1)OCCn1cc(-c3nc(C)nn3C(C)C)nc1-2.C[Mg]Br>>CC(=O)c1ccc2c(c1)OCCn1cc(-c3nc(C)nn3C(C)C)nc1-2,,CCOCC,,C1CCOC1,,test
US20130310395A1,O=C(Nc1ccc(OC(F)(F)F)c(F)c1)c1cnc(N2CC[C@@H](O)C2)c(Br)c1.c1cn[nH]c1>>O=C(Nc1ccc(OC(F)(F)F)c(F)c1)c1cnc(N2CC[C@@H](O)C2)c(-c2ccn[nH]2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20090149458A1,CN(C)/C=C/c1nc(-c2cccc(OCc3ccccc3)c2)nc(N2CCOCC2)c1[N+](=O)[O-]>>c1ccc(COc2cccc(-c3nc(N4CCOCC4)c4[nH]ccc4n3)c2)cc1,[Pd],CO,,,,test
US20060142348A1,CS(=O)(=O)Cl.Cc1c[nH]c2c(-c3ccc(N)cc3)cc(F)cc12>>Cc1c[nH]c2c(-c3ccc(NS(C)(=O)=O)cc3)cc(F)cc12,,c1ccncc1,,,,test
US20130172302A1,O=C(CBr)c1nccs1.O=C(O[C@H]1CN2CCC1CC2)C(c1ccccc1)N1CCCCC1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C(c1ccccc1)N1CCCCC1)C2)c1nccs1.[Br-],,CCOC(C)=O,,,,test
US07074777B2,CC(C)(C)[Si](C)(C)O[C@H]1C[C@H](O[Si](C)(C)C(C)(C)C)CC2=CC=C3[C@@H]4CC=C(CO)[C@@]4(C)CC[C@@H]3[C@]21C.CCC(CC)(CCCBr)O[Si](CC)(CC)CC>>CCC(CC)(CCCOCC1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C)O[Si](CC)(CC)CC,,C1CCOC1,,C1COCCOCCOCCOCCO1,[H-].[Na+],test
US20040260088A1,CNC.N#Cc1ccc(Cl)cc1Oc1cccc(C=O)c1.O=C(O)/C=C/C(=O)O>>CN(C)Cc1cccc(Oc2cc(Cl)ccc2C#N)c1.O=C(O)/C=C/C(=O)O,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US05637770,CC(=O)Nc1cccc2c1C(=O)C(=NO)CC2.CC(=O)OC(C)=O>>CC(=O)Nc1cccc2c1C(=O)C(NC(C)=O)CC2,[Zn],CC(=O)OC(C)=O,,CC(=O)O,,test
US20080188506A1,Cc1ccccc1C1NC(=O)C(C)C(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12>>Cc1ccccc1C1NCC(C)C(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12,,CO,,[BH4-].[Na+],,test
US20080171786A1,NC(=O)c1cc([N+](=O)[O-])ccc1I.OB(O)c1cc2ccccc2s1>>NC(=O)c1cc([N+](=O)[O-])ccc1-c1cc2ccccc2s1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20040067968A1,Brc1cccnc1.Cn1c(=O)cc(CCc2ccc(Cl)s2)c2cc(C(=O)c3ccc(Cl)cc3)ccc21>>Cn1c(=O)cc(CCc2ccc(Cl)s2)c2cc(C(O)(c3ccc(Cl)cc3)c3cccnc3)ccc21,,CCOCC,O,C1CCOC1,[Li]CCCC,test
US06309882B1,COCCO.Cc1cn2c(nc1=O)O[C@H]1[C@H](O)[C@@H](CO)O[C@H]12>>COCCO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(C)c(=O)[nH]c1=O,,COCCO,,,,test
US05935963,CC(C)(C)OC(=O)c1ccc(C#N)cc1.NO>>CC(C)(C)OC(=O)c1ccc(C=NO)cc1,,CO,,CCN(CC)CC,,test
US20090270374A1,C=CCn1c(=O)ccc2ccc(C#N)nc21.O=[Os](=O)(=O)=O>>N#Cc1ccc2ccc(=O)n(CC=O)c2n1,O=[Os](=O)(=O)=O,C1COCCO1,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20090306123A1,CC(C)(C)OC(=O)N1CC2CC(=O)CC(C1)N2C(=O)OC(C)(C)C.COC(=O)OC>>COC(=O)C1C(=O)CC2CN(C(=O)OC(C)(C)C)CC1N2C(=O)OC(C)(C)C,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20040204397A1,O=[N+]([O-])c1ccccc1CNC1CCN(Cc2ccccc2)CC1>>Nc1ccc(O)cc1CNC1CCN(Cc2ccccc2)CC1,[Zn],,,CC(=O)O,,test
US20020165203A1,CC(=O)Cl.CN(CC(=O)O)C(=O)OC(C)(C)C.NC(=O)c1ccc2c(c1)OCO2>>CNCC(=O)O.Cl.NC(=O)c1ccc2c(c1)OCO2,,CO,,,,test
US20100298351A1,Cc1cc(C)cc(-n2ncc(C(N)=O)c2N)c1.NC=O>>Cc1cc(C)cc(-n2ncc3c(=O)[nH]cnc32)c1,,O,,,,test
US20160016966A1,Cl.Cn1cc(-c2ccc(CNC(=O)OC(C)(C)C)cc2)c2oc(CN3CCN(S(C)(=O)=O)CC3)cc2c1=O>>Cl.Cn1cc(-c2ccc(CN)cc2)c2oc(CN3CCN(S(C)(=O)=O)CC3)cc2c1=O,,C1COCCO1,,,,test
US20140134109A1,O=C1NN(CO)C=C(Cl)C1Cl.O=S(Cl)Cl>>ClCN1C=C(Cl)C(Cl)=CN1,,ClCCl,O,CN(C)C=O,O=C([O-])O.[Na+],test
US04820727,CCOC(=O)N(CC(=O)OC(C)(C)C)C(=O)c1c(Br)ccc2c(C(F)(F)F)c(OC)ccc12>>CCOC(=O)N(CC(=O)O)C(=O)c1c(Br)ccc2c(C(F)(F)F)c(OC)ccc12,,O,O=CO,,,test
US20020128301A1,CCOC(=O)C1CCC(O)CC1.COc1ccc(CCl)cc1>>COc1ccc(COC(=O)C2CCC(O)CC2)cc1,,CCO,,[K+].[OH-],,test
US20130059853A1,COCOc1c(-c2ccc3c(c2)COC3=O)ccc(OC)c1OC(F)F>>COc1ccc(-c2ccc3c(c2)COC3=O)c(O)c1OC(F)F,,CO,,Cl,,test
US20110105461A1,CC(C)N.Cc1ccc(S(=O)(=O)OCC2CCc3ccc(S(C)(=O)=O)cc3O2)cc1>>CC(C)NCC1CCc2ccc(S(C)(=O)=O)cc2O1,,CC#N,,,,test
US04791127,CS(=O)(=O)Cl.O=C1CSC(SCCCF)=N1>>CS(=O)(=O)Oc1csc(SCCCF)n1,,ClCCl,,CCN(CC)CC,O,test
US20110190336A1,CC(C)(C)OC(=O)N1CCC(Nc2ncccc2N)CC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3cccnc32)CC1,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20140323477A1,CCn1c(=O)c(-c2ccc(S(=O)(=O)NC3CC3)cc2C)cc2cnc(S(C)=O)nc21.CN1CCC(CCN)CC1>>CCn1c(=O)c(-c2ccc(S(=O)(=O)NC3CC3)cc2C)cc2cnc(NCCC3CCN(C)CC3)nc21,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US04263037,CC1(C)c2cc(C#N)ccc2OC1O.O=C(Cl)CCl>>CC1(C)c2cc(C#N)ccc2OC1OC(=O)CCl,,CCOCC,,CCN(CC)CC,O,test
US20100168418A1,COc1ccc2ncc(=O)n(CCN3CCC(N(Cc4ccc5c(c4)OCCO5)C(=O)OC(C)(C)C)CC3)c2c1.Cl>>COc1ccc2ncc(=O)n(CCN3CCC(NCc4ccc5c(c4)OCCO5)CC3)c2c1.Cl,,CCOC(C)=O,,CO,,test
US20110144090A1,CI.Fc1cc(Br)c2[nH]ccc2c1OCc1ccccc1>>Cn1ccc2c(OCc3ccccc3)c(F)cc(Br)c21,,CN(C)C=O,,O,[K+].[OH-],test
US20110319406A1,COC(OC)c1nc(-c2ccc3ncnn3c2)c(-c2cccc(C)n2)[nH]1>>Cc1cccc(-c2[nH]c(C=O)nc2-c2ccc3ncnn3c2)n1,,Cl,,O=C([O-])O.[Na+],,test
US20160222028A1,COC(=O)c1ccc(CNCC(O)C(=O)N(C)C)c(Br)c1>>COC(=O)c1ccc2c(c1)OC(C(=O)N(C)C)CNC2,[Cu]I,CC(C)O,,O=C([O-])[O-].[K+].[K+],,test
US20100305096A1,C1CCNC1.CC(C)(C)OC(=O)N1CCC(C)(C(=O)O)CC1>>CC(C)(C)OC(=O)N1CCC(C)(C(=O)N2CCCC2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130190312A1,Cc1cc(O)cc(C)c1-c1csc(NC(=O)c2ccncc2)n1.Oc1ccc(Br)cn1>>Cc1cc(Oc2ccc(O)nc2)cc(C)c1-c1csc(NC(=O)c2ccncc2)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06143750,N#Cc1ccccc1N1CCC(N2CC[C@@H](NC(=O)N3C(=O)O[C@@H](COC4CCCCO4)[C@@H]3c3ccc(F)c(F)c3)C2)CC1>>N#Cc1ccccc1N1CCC(N2CC[C@@H](NC(=O)N3C(=O)O[C@@H](CO)[C@@H]3c3ccc(F)c(F)c3)C2)CC1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20140088078A1,CCN1CC[C@@H](CN)C1.O=C(O)c1c(NS(=O)(=O)c2ccccc2F)ccc2c1OCC1CC21>>CCN1CC[C@@H](CNc2ccccc2S(=O)(=O)Nc2ccc3c(c2C(=O)O)OCC2CC32)C1,,CO,CS(C)=O,,,test
US20050096389A1,CCC(=O)Cl.O.OCC1(CO)c2ccccc2-c2ccccc21.c1ccncc1>>CCC(=O)OCC1(COC(=O)CC)c2ccccc2-c2ccccc21,,O,,C1CCOC1,,test
US20130158059A1,Cc1cn(-c2cc(NC(=O)c3ccc(C)c(Nc4nccc(-c5cccnc5)n4)c3)cc(C(F)(F)F)c2)cn1.O=C(O)C(=O)O>>Cc1cn(-c2cc(NC(=O)c3ccc(C)c(Nc4nccc(-c5cccnc5)n4)c3)cc(C(F)(F)F)c2)cn1.O=C([O-])C(=O)[O-],,CCO,,CN(C)C=O,,test
US20090253740A1,CCOC(=O)c1cnc2cc(C(C)(C)C)ccc2c1>>CC(C)(C)c1ccc2cc(C(=O)O)cnc2c1,,CCO,,[Na+].[OH-],,test
US04782164,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)Oc1c(F)c(F)c(F)c(F)c1F.CCOC(=O)CN>>CCOC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C,,C1COCCO1,CCOC(C)=O,CCN(CC)CC,,test
US20040082781A1,CCc1nc2c(Br)nc(C)cn2c1C(=O)OC.OB(O)c1ccc(Cl)cc1Cl>>CCc1nc2c(-c3ccc(Cl)cc3Cl)nc(C)cn2c1C(=O)OC,,CO,Cc1ccccc1,,,test
US05965591,CC(C)(C)OC(=O)NCCSc1noc2ccc(F)cc12.Cl>>Cl.NCCSc1noc2ccc(F)cc12,,C1COCCO1,,,,test
US20100197678A1,O=C1CCC(=O)N1Br.O=c1[nH]cnc2cc[nH]c12>>O=c1[nH]cnc2c(Br)c[nH]c12,,CN(C)C=O,O,,,test
US04830470,CCCCCCC[C@@H]1CC[C@@H](CBr)CC1.Oc1ccc(O)cc1>>CCCCCCC[C@@H]1CC[C@@H](COc2ccc(O)cc2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080242665A1,CS(=O)(=O)N1CCN(Cc2cc3nc(-c4ccc(N)nc4)nc(N4CCOCC4)c3o2)CC1.O=C=NS(=O)(=O)Cl>>CS(=O)(=O)N1CCN(Cc2cc3nc(-c4ccc(NC(N)=O)nc4)nc(N4CCOCC4)c3o2)CC1,,CC#N,,[Na+].[OH-],,test
US20070287843A1,CC(=O)O.CC12CCC3C(C1O2)C3(C)C>>CC1(O)C=CC(C(C)(C)O)CC1,,CCCCCCC,,O,,test
US20140187542A1,CC(C)(C)[Si](OCC(F)CI)(c1ccccc1)c1ccccc1.COc1ccc2ncc(=O)[nH]c2c1>>COc1ccc2ncc(=O)n(CC(F)CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)c2c1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20090312381A1,CC(C)(N)c1cccc(C(F)(F)F)c1.O=C(Cl)CCl>>CC(C)(NC(=O)CCl)c1cccc(C(F)(F)F)c1,,ClCCl,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20050176767A1,COc1cc(OC)c(OCc2ccccc2)c(C(=O)NCc2ccc(F)cc2)n1>>COc1cc(OC)c(O)c(C(=O)NCc2ccc(F)cc2)n1,[Pd],CO,,,,test
US20060178507A1,CN(C)c1ccc(N=Nc2ccc(C(=O)O)cc2)cc1.COC(=O)C(CN)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>COC(=O)C(CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)CNC(=O)c1ccc(N=Nc2ccc(N(C)C)cc2)cc1,,ClCCl,c1ccncc1,CCN(C(C)C)C(C)C,O,test
US20150080393A1,O=C(O)c1ccc(Br)cc1N1CCN(C(=O)OCc2ccccc2)CC1>>O=C(OCc1ccccc1)N1CCN(c2cc(Br)ccc2CO)CC1,,C1CCOC1,,B,,test
US20110118230A1,CCNC(=O)OCC.Fc1cc(Br)ccc1CN1CCCCC1.O>>CCOc1cc(Br)ccc1CN1CCCCC1,,C1COCCO1,O,[H-].[Na+],,test
US20090082379A1,CC1(C)NC(=O)N(c2ccc(SC(F)(F)F)c(N)c2)C1=O.ClCc1ccnc(Cl)c1>>CC1(C)C(=O)N(c2ccc(SC(F)(F)F)c(N)c2)C(=O)N1Cc1ccnc(Cl)c1,,CN(C)C=O,,[H-].[Na+],,test
US20040082780A1,CC(=O)Nc1nc2c(O)cccc2s1.CC(C)(C)OC(=O)Nc1cc(C(F)(F)F)ccc1-c1cc(Cl)ncn1>>CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4NC(=O)OC(C)(C)C)ncn3)cccc2s1,,CN(C)C=O,,[H-].[Na+],,test
US20110300165A1,CC(C)(C)OC(=O)C1CN(Cc2ccc(/C(N)=N/O)cc2)C1.CC(F)(F)c1c(C(=O)O)noc1-c1ccccc1.CCN(C(C)C)C(C)C>>CCC(F)(F)c1c(-c2nc(-c3ccc(CN4CC(C(=O)OC(C)(C)C)C4)cc3)no2)noc1-c1ccccc1,,CC#N,,ClCCCl,On1nnc2ccccc21,test
US20130338081A1,C=O.N[C@@H](Cc1cc(I)c(O)c(I)c1)C(=O)O>>O=C(O)[C@@H]1Cc2cc(I)c(O)c(I)c2CN1,,COCCOC,,Cl,,test
US04472383,Br.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N(CC(=O)N[C@@H](Cc1ccccc1)C(=O)OC(C)(C)C)C1Cc2ccccc2C1>>Br.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N(CC(=O)N[C@@H](Cc1ccccc1)C(=O)O)C1Cc2ccccc2C1,,CC(=O)O,,CCOCC,,test
US20150239842A1,COC(=O)c1cc(C#N)cc(N)c1C.ICI>>COC(=O)c1cc(C#N)cc(I)c1C,,CC#N,,CC(C)(C)ON=O,,test
US20140163077A1,CC(C)N(Cc1cccc(-c2ccncc2)c1)C(=O)Cl.CNC(=O)c1ccc(-c2ccc(O)cc2)cc1>>CCCN(Cc1cccc(-c2ccncc2)c1)C(=O)Oc1ccc(-c2ccc(C(=O)NC)cc2)cc1,,ClCCl,,CCN(CC)CC,,test
US20120115844A1,Cn1nnc(-c2ccc(F)cc2)c1COc1ccc(C(=O)O)cn1.NC1CCOCC1>>CC(C)NC(=O)c1ccc(OCc2c(-c3ccc(F)cc3)nnn2C)nc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20050192310A1,BrP(Br)Br.OCc1ccncc1I>>Br.BrCc1ccncc1I,,C1CCOC1,,ClCCl,,test
US05334716,CCCCCC(Br)c1ccc(CC(C)C)cc1.CCOC(=O)CCCc1cc(C(=O)c2cccc(N)c2)c2ccccn12>>CCCCCC(Nc1cccc(C(=O)c2cc(CCCC(=O)OCC)n3ccccc23)c1)c1ccc(CC(C)C)cc1,,ClCCl,O,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20110201604A1,CCOCCN.CCn1c(Nc2nc3ccc(C(F)(F)F)cc3s2)nc2cc(C(=O)O)ccc21>>CCOCCNC(=O)c1ccc2c(c1)nc(Nc1nc3ccc(C(F)(F)F)cc3s1)n2CC,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090306373A1,CC(=O)OC(C)=O.CC1=C(C(=O)OCCN)C(c2ccccc2F)c2c(sc(C(=O)c3ccc(Cl)c(Cl)c3)c2N)N1>>CC(=O)NCCOC(=O)C1=C(C)Nc2sc(C(=O)c3ccc(Cl)c(Cl)c3)c(N)c2C1c1ccccc1F,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20100210651A1,COC(=O)c1cc(OCc2c(-c3ccccn3)noc2C)no1>>Cc1onc(-c2ccccn2)c1COc1cc(C(=O)O)on1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20090156575A1,C=C(C)CCl.COC(=O)c1cccc(O)c1>>C=C(C)COc1cccc(C(=O)OC)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030158197A1,CCOc1ccc(CCN)cc1OC.Cc1cc(C)c(-n2cnc3c(NCCCl)cc(C)nc32)c(C)c1>>CCOc1ccc(CCNCCNc2cc(C)nc3c2ncn3-c2c(C)cc(C)cc2C)cc1OC,,CN1CCCC1=O,,,,test
US20080261941A1,FC(F)(F)COc1ccc(Oc2cccc(C=C3CCNCC3)c2)nc1.O=C(Nc1cccnc1)Oc1ccccc1>>O=C(Nc1cccnc1)N1CCC(=Cc2cccc(Oc3ccc(OCC(F)(F)F)cn3)c2)CC1,,CS(C)=O,O,CCN(CC)CC,,test
US07125887B2,COC(=O)C(C)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1.NN>>Cc1c(C2CCN(C(=O)OC(C)(C)C)CC2)[nH][nH]c1=O,,Cc1ccccc1,,,,test
US20080207891A1,CCCc1nccn1-c1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O>>CCCc1nccn1-c1nc(Cl)nc2nc[nH]c12,,CC(=O)O,,CC(=O)Cl,,test
US06248736B1,CC(O)Br.O=C(NCc1ccc(Cl)cc1)c1cnc2ccc(C#CCO)cc2c1O>>O=C(NCc1ccc(Cl)cc1)c1cn(CCO)c2ccc(C#CCO)cc2c1=O,,CO,O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US05543523,BrBr.COc1cc2c(c(OC)c1)[C@@H](C)N(Cc1ccccc1)[C@H](C)C2>>COc1cc(OC)c2c(c1Br)C[C@@H](C)N(Cc1ccccc1)[C@@H]2C,,ClCCl,,,,test
US20110282018A1,CI.COc1ccc(OC2CCCCO2)cc1>>COc1ccc(OC2CCCCO2)c(C)c1,,C1CCOC1,,O,[Li]CCCC,test
US20130029980A1,C=CCc1ccc(CCCn2c3nc(=O)[nH]c(=O)c-3[n+]([O-])c3cc(C)c(CC=C)cc32)cc1>>C=CCc1ccc(CCCn2c3nc(=O)[nH]c(=O)c-3nc3cc(C)c(CC=C)cc32)cc1,,CCO,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20090137557A1,Cc1ccc(B(O)O)s1.Cc1nc(-c2cccc(F)c2OCc2ccccc2)n(CCc2ccccc2)c(=O)c1Br>>Cc1ccc(-c2c(C)nc(-c3cccc(F)c3O)n(CCc3ccccc3)c2=O)s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US04508906,CCOC(=O)C=CC(C)Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1.N>>CCOC(=O)CC(N)C(C)Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1,,CCO,,,,test
US20030225179A1,CC(C)(C(=O)c1ccc(F)cc1)N1CCOCC1.CC(O)S>>CC(C)(C(=O)c1ccc(SCCO)cc1)N1CCOCC1,,Cc1ccccc1,,O,[Na+].[OH-],test
US20160137639A1,CC(C)CCC1CCC(=O)C2C([C@@H](CCCOCc3ccccc3)CC(=O)OC(C)(C)C)=NOC12>>CC(C)CCC1CCC(=O)c2c([C@@H](CCCOCc3ccccc3)CC(=O)OC(C)(C)C)noc21,,Cc1ccccc1C,,,,test
US20080292585A1,CN(C)CCN1C(=O)c2cccc3cc4cccc(N)c4c(c23)C1=O.O=C(Cl)CCCCl>>CN(C)CCN1C(=O)c2cccc3cc4cccc(NC(=O)CCCCl)c4c(c23)C1=O,,CC#N,,CO,ClCCl,test
US20040122057A1,CCOC(=O)CBr.CCOC(C(=O)NCc1ccc(C#N)cc1)c1c(F)cc(Br)cc1F.OB(O)c1cccc(O)c1>>CCOC(=O)COc1cccc(-c2cc(F)c(C(OCC)C(=O)NCc3ccc(C#N)cc3)c(F)c2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080242655A1,CCOC(=O)c1[nH]c2c(Cl)cncc2c1Nc1ccc([Si](C)(C)C)cc1F.ClI>>CCOC(=O)c1[nH]c2c(Cl)cncc2c1Nc1ccc(I)cc1F,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US05703072,CC(C)(C)O[C@H]1C[C@H]2CN(C3=Nc4cc(Cl)ccc4Sc4ccccc43)CCN2C1>>O[C@H]1C[C@H]2CN(C3=Nc4cc(Cl)ccc4Sc4ccccc43)CCN2C1,,O=C(O)C(F)(F)F,,CCN(CC)CC,,test
US20050014725A1,CC(C)(C)OC(=O)CCNCc1ccc2nc(-c3ccc(-c4ccccc4)c(C(F)(F)F)c3)sc2c1>>O=C(O)CCNCc1ccc2nc(-c3ccc(-c4ccccc4)c(C(F)(F)F)c3)sc2c1,,ClCCl,O=C(O)C(F)(F)F,,,test
US05998459,CCOC(=N)CC#N.N#CCC(=N)N.O=C1c2ccccc2OCC1Br>>N#Cc1c(N)[nH]c2c1COc1ccccc1-2,,CCO,,Cl,,test
US20150252022A1,O=C(OCc1ccccc1)N1CCC(Cn2ccc3cc(-c4cnn(C5CCCCO5)c4)ccc32)C1>>c1cc2c(ccn2CC2CCNC2)cc1-c1cnn(C2CCCCO2)c1,[Pd],CCO,,CO,ClCCl,test
US20070299072A1,CON.COc1ccc(CCN2C(=O)C3(CCNCC3)N(C)C2c2ccc(C3CC3)cc2)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CONC(=O)N1CCC2(CC1)C(=O)N(CCc1ccc(OC)cc1)C(c1ccc(C3CC3)cc1)N2C,,CCOC(C)=O,ClCCl,CCN(CC)CC,Cl,test
US20020161014A1,COc1ccccc1-n1c(CCl)nc2cccc(Cl)c2c1=O.Nc1ncnc2nc[nH]c12>>COc1ccccc1-n1c(Cn2cnc3c(N)ncnc32)nc2cccc(Cl)c2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040242884A1,CNCC(O)c1ccoc1.Cc1c(CCl)sc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12>>Cc1c(CN(C)CC(O)c2ccoc2)sc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,,test
US04892872,CN1C(=O)COc2c(C(=O)O)cccc21.O=[N+]([O-])O>>CN1C(=O)COc2c(C(=O)O)cc([N+](=O)[O-])cc21,,O=S(=O)(O)O,,,,test
US05484955,CCCCCCCC[Sn](CCCCCCCC)(CCCCCCCC)N=[N+]=[N-].CCOc1nc2cccc(C(=O)OC)c2n1Cc1ccc(-c2ccccc2C#N)cc1>>CCOc1nc2cccc(C(=O)OC)c2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,Cc1ccccc1,,,,test
US20150166512A1,CCOC(CNC(=CC#N)c1cc(Cl)ccc1C)OCC>>Cc1ccc(Cl)cc1-c1[nH]ccc1C#N,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060167315A1,CSCC(C)(C)N.O=C(Cl)OCc1ccccc1>>CSCC(C)(C)NC(=O)OCc1ccccc1,,C1CCOC1,Cc1ccccc1,CCN(CC)CC,,test
US20130096118A1,COC(=O)c1cc2ccc(O)cc2[nH]1.COCCBr>>COCCOc1ccc2cc(C(=O)OC)[nH]c2c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130331382A1,CS(=O)(=O)Cl.Cc1cc(Oc2ccccc2)c(-c2ccc(=O)n(C)c2)cc1N>>Cc1cc(Oc2ccccc2)c(-c2ccc(=O)n(C)c2)cc1NS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US03937723,CCOC(=O)C(C)=CC1=C(C)CCC1C(C)C>>CC(=CC1=C(C)CCC1C(C)C)CO,,CCOCC,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US06046350,Cl[Si](Cl)(Cl)Cl.[Li]C(C)(C)CC>>CCC(C)(C)[Si](Cl)(Cl)Cl,,CCOCC,,,,test
US20090099205A1,Cc1cc(N)nc(C)c1Br.O=CCCl>>Cc1cc2nccn2c(C)c1Br,,ClCCl,,Cc1ccccc1,O=C([O-])O.[Na+],test
US05344843,CCO/N=C(\C(=O)OCC)c1ccc(OCCOc2ccc3ccccc3c2)s1>>CCO/N=C(\C(=O)O)c1ccc(OCCOc2ccc3ccccc3c2)s1,,C1CCOC1,CO,[Na+].[OH-],,test
US20110015196A1,C=C(C)[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(C)=O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CC1(C)[C@@H](N)C[C@H]1C(=O)N1CCOCC1>>C=C(C)[C@@H]1CC[C@]2(C(=O)N[C@H]3C[C@@H](C(=O)N4CCOCC4)C3(C)C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(C)=O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20090018122A1,CC(=O)OCC(=O)Nc1cnc2cc(OCc3ccccc3)ccc2c1NCC(C)(C)O>>CC(C)(O)Cn1c(CO)nc2cnc3cc(OCc4ccccc4)ccc3c21,,CO,O,Cl,[Na+].[OH-],test
US20100286145A1,CC(C)=O.CC(C)[Si](OCc1cncc(Br)c1)(C(C)C)C(C)C>>CC(C)[Si](OCc1cncc(C(C)(C)O)c1)(C(C)C)C(C)C,,Cc1ccccc1,,[Li]CCCC,,test
US04418197,COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCCCCOS(=O)(=O)c2ccc(C)cc2)C1c1cccc(Cl)c1Cl.COc1ccc(C2=CC(=O)N=N2)cc1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCCCCOc2cc(-c3ccc(OC)cc3)[nH]n2)C1c1cccc(Cl)c1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20130072467A1,COC[C@@H](NC1=NC(=O)SC1)C(=O)N(C)C.O=CC1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1>>COC[C@@H](NC1=NC(=O)S/C1=C\C1CCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1)C(=O)N(C)C,,CC(C)O,,C1CC[NH2+]CC1.CC(=O)[O-],,test
US05935542,CCN(CC)CC.CCOP(=O)(C#N)OCC>>CCOP(=O)([O-])C#N.CC[NH+](CC)CC,,CC(=O)N(C)C,,Cl,,test
US05556864,ClCCN1CCOCC1.Oc1ccccc1CCCCc1ccccc1>>c1ccc(CCCCc2ccccc2OCCN2CCOCC2)cc1,,CC(=O)N(C)C,,Cl,[H-].[Na+],test
US06432993B1,CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(-c3ccccc3)cc2)ccc1[N+](=O)[O-]>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(-c3ccccc3)cc2)ccc1N,[Pd],CCCCCC,CCOC(C)=O,Cc1ccccc1,,test
US20070293507A1,Nc1ccccc1N.O=C(O)c1cc(-c2ccccc2)n[nH]1>>Nc1ccccc1NC(=O)c1cc(-c2ccccc2)n[nH]1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US03951976,C#CCN1CCC(O)N(c2nnc(S(C)=O)s2)C1=O.Cc1cc(Br)ccc1N=C=O>>C#CCN1CCC(OC(=O)Nc2ccc(Br)cc2C)N(c2nnc(S(C)=O)s2)C1=O,CCN(CC)CC,,,,,test
US05168103,CCOP(=O)(CCN)OCC.CCOc1c(OCC)c(=O)c1=O>>CCOc1c(NCCP(=O)(OCC)OCC)c(=O)c1=O,,CCO,,,,test
US20090181942A1,CC(=O)NN.CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2NC1=S>>CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2-n2c(C)nnc21,,CC(C)O,,,,test
US20100029737A1,COC(=O)c1cc2c([nH]1)CC=C2c1ccc(-c2ccccc2)cc1>>COC(=O)c1cc2c([nH]1)CCC2c1ccc(-c2ccccc2)cc1,[Pd],,,,,test
US20150080364A1,CC1(C)CN(Cc2ccc(N3CCOCC3)cc2C(F)(F)F)CCN1.O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O>>CC1(C)CN(Cc2ccc(N3CCOCC3)cc2C(F)(F)F)CCN1C(=O)ON1C(=O)CCC1=O,,CC#N,,CCN(CC)CC,,test
US20090274947A1,CC(=O)OC(C)=O.CC1(C)CC2(CNC(C)(C)N2)CC(C)(C)N1>>CC(=O)N1CC2(CC(C)(C)NC(C)(C)C2)NC1(C)C,,ClC(Cl)Cl,O,[Na+].[OH-],,test
US20030220495A1,COC(=O)c1ccc(CC(=Cn2cncc2C)c2ccc(F)cc2)cc1-c1ccccc1>>COC(=O)c1ccc(CC(Cn2cncc2C)c2ccc(F)cc2)cc1-c1ccccc1,[Pd],CO,,,,test
US20090062558A1,CS(=O)(=O)Cl.OCCCC=CCCC(F)(F)C(F)(F)F>>CS(=O)(=O)OCCCC=CCCC(F)(F)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20080027070A1,NCCN1CCCC1.O=S(=O)(Cl)c1cccc(Br)c1>>O=S(=O)(NCCN1CCCC1)c1cccc(Br)c1,,C1CCOC1,,,,test
US20150031679A1,C1COCCN1.COC(=O)c1ccc2nc(-c3ccccc3)c(Br)nc2c1>>COC(=O)c1ccc2nc(-c3ccccc3)c(N3CCOCC3)nc2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20090156707A1,O=C(Cl)C(=O)Cl.O=C(O)CCCCC(=O)OCc1ccccc1>>O=C(Cl)CCCCC(=O)OCc1ccccc1,,ClC(Cl)Cl,,,,test
US20130338177A1,CN1C(=O)C2(N=C1N)c1cc(O)ccc1Oc1ccc(-c3cccnc3F)cc12.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CN1C(=O)C2(N=C1N)c1cc(OS(=O)(=O)C(F)(F)F)ccc1Oc1ccc(-c3cccnc3F)cc12,,ClCCl,,,,test
US20160016914A1,CC1(C)CO1.CCOC(=O)c1n[nH]c2ccccc12>>CCOC(=O)c1nn(CC(C)(C)O)c2ccccc12,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110269804A1,COC(=O)c1ccc(Br)c2oc(C)nc12>>Cc1nc2c(CO)ccc(Br)c2o1,,C1CCOC1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20050222261A1,CCCCCCCNCc1ccc(F)cc1F.O=C(Cl)CBr>>CCCCCCCN(Cc1ccc(F)cc1F)C(=O)CBr,,ClCCl,,CCN(CC)CC,,test
US20120157428A1,CS(=O)(=O)Cl.Cc1onc(CO)c1-c1ccccc1C(=O)c1ccc(Cl)cc1>>Cc1onc(COS(C)(=O)=O)c1-c1ccccc1C(=O)c1ccc(Cl)cc1,,O,,CCN(CC)CC,ClCCl,test
US20160264575A1,CC(C)(C)OC(=O)CCN.S=C(Cl)Cl>>CC(C)(C)OC(=O)CCN=C=S,,ClCCl,O,Cl,O=C([O-])O.[Na+],test
US20050222140A1,C/C=C/[C@@H](c1ccc(-c2ccc(F)cc2)cc1)[C@H](NC(=O)OC(C)(C)C)C(=O)OC>>C/C=C/[C@@H](c1ccc(-c2ccc(F)cc2)cc1)[C@H](NC(=O)OC(C)(C)C)C(=O)O,,C1CCOC1,CO,[Li+].[OH-],,test
US20160016948A1,CC(C)(C)OC(=O)CCN.Cc1nc2cnc(Nc3ccnc(Cl)n3)cc2n1C(C)C>>Cc1nc2cnc(Nc3ccnc(NCCC(=O)OC(C)(C)C)n3)cc2n1C(C)C,,CC(C)O,,CCN(C(C)C)C(C)C,Cl,test
US06258775B1,C=C(c1cccc(C(=O)OC)c1)c1ccc2c(c1)C(C)(C)CCC2(C)C>>COC(=O)c1cccc(C(C)c2ccc3c(c2)C(C)(C)CCC3(C)C)c1,[Pd],CCOC(C)=O,,[H][H],,test
US20100160628A1,CN(C)S(=O)(=O)Cl.COc1cc(O)c(C=O)cc1OC>>COc1cc(C=O)c(OS(=O)(=O)N(C)C)cc1OC,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100197908A1,CC(C)(C)OC(=O)N1CC[C@@H](C(=O)O)C1.CNC>>CN(C)C(=O)[C@@H]1CCN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,,,test
US05006548,CCOC(=O)OC(C)Cl.O=C(C=Cc1cccs1)Nc1ccccc1C(=O)O>>CCOC(=O)OC(C)OC(=O)c1ccccc1NC(=O)C=Cc1cccs1,,CC(C)=O,,CCN(CC)CC,[I-].[Na+],test
US20040038959A1,CC(C)(C)OC(=O)c1ccc(CBr)cc1.Oc1cc2ccc(Br)cc2cn1>>CC(C)(C)OC(=O)c1ccc(Cn2cc3cc(Br)ccc3cc2=O)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05726165,CCCCCC[PH](=O)O.CCCCO>>CCCCCC[PH](=O)OCCCC,,CCCCO,,,,test
US20150158828A1,CO.O=C(O)c1ccc(S)cc1>>COC(=O)c1ccc(S)cc1,O=S(=O)(O)O,ClC(Cl)Cl,,,,test
US20050080124A1,COc1ccc(N)cc1-c1c(Cl)c(C(F)(F)F)nn1C.O=C=Nc1ccc(F)cc1>>COc1ccc(NC(=O)Nc2ccc(F)cc2)cc1-c1c(Cl)c(C(F)(F)F)nn1C,,ClCCl,,,,test
US20110218200A1,CN(C)C(=O)Cl.O=[N+]([O-])c1ccc(N2CCNCC2)cc1Nc1ccccc1>>CN(C)C(=O)N1CCN(c2ccc([N+](=O)[O-])c(Nc3ccccc3)c2)CC1,,ClCCl,,CCN(CC)CC,,test
US20110195986A1,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)O.CCS(=O)(=O)C[C@@H](O)COc1ccc(N2Cc3cc(-c4ccc(Cl)cc4)sc3C2=O)cc1OC>>CCS(=O)(=O)C[C@H](COc1ccc(N2Cc3cc(-c4ccc(Cl)cc4)sc3C2=O)cc1OC)OC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C,CN(C)c1ccncc1,ClCCl,,CC(C)N=C=NC(C)C,,test
US20140213642A1,C=CCOc1cc(Cl)c(Cc2ccc(OCC)cc2)cc1[C@@H]1O[C@H](CO)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1.CC(C)(C)[Si](OCCCCCBr)(c1ccccc1)c1ccccc1>>C=CCOc1cc(Cl)c(Cc2ccc(OCC)cc2)cc1[C@@H]1O[C@H](COCCCCCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20100197656A1,O=C(O)c1cccc(Nc2nc(Cl)nc3c2SCC3)c1.Oc1ccc(N2CCNCC2)cc1>>Oc1ccc(N2CCN(c3nc(O)c4c(n3)CCS4)CC2)cc1,,O,,CC(=O)O,,test
US20110152240A1,Cc1c(N2CCN(c3ncccc3C#N)CC2)nc2c(C=O)cnn2c1NC1CC1.O=C1CNC(=O)N1>>Cc1c(N2CCN(c3ncccc3C#N)CC2)nc2c(C=C3NC(=O)NC3=O)cnn2c1NC1CC1,,CCO,O,C1CCNCC1,,test
US20030069238A1,Brc1cccc(Nc2ncc(Br)s2)n1.Cc1ccc(S)cc1C(=O)O>>Cc1ccc(Sc2cnc(Nc3cccc(Br)n3)s2)cc1C(=O)O,,C1CCOC1,CO,C[O-].[Na+],,test
US04914103,BrCCc1ccccc1.CN1c2ccncc2N=Cc2cccn21>>CN1c2ccncc2NC(CCc2ccccc2)c2cccn21,,C1CCOC1,CCOCC,[Mg],[Cl-].[NH4+],test
US20110105578A1,CCCCc1nc(-c2ccc(OC[C@@H]3CO3)cc2)cn1-c1ccc(Oc2ccc(Cl)cc2)cc1.CCN>>CCCCc1nc(-c2ccc(OC[C@@H](O)CNCC)cc2)cn1-c1ccc(Oc2ccc(Cl)cc2)cc1,,CO,,,,test
US20020007074A1,CC(=O)c1ccc(CC(C)C)cc1.O=Cc1cncn1Cc1ccccc1>>CC(C)Cc1ccc(C(=O)C=Cc2cncn2Cc2ccccc2)cc1,,CO,,[Na+].[OH-],,test
US20130089512A1,CC1(C)OB(c2cnn3cc(F)ccc23)OC1(C)C.C[Si](C)(C)CCOCn1c(=O)n(C2CCOCC2)c2nc(Cl)ncc21>>C[Si](C)(C)CCOCn1c(=O)n(C2CCOCC2)c2nc(-c3cnn4cc(F)ccc34)ncc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,CC(=O)[O-].[K+],,test
US20130131018A1,CCOC(CN)OCC.CCOc1cccc(C=O)c1O>>CCOc1cccc(CNCC(OCC)OCC)c1O,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US20150080583A1,C1CN2CCOC2O1.O=[N+]([O-])c1cccc(CCl)c1>>O=[N+]([O-])c1cccc(C[N+]23CCOC2OCC3)c1.[Cl-],,ClC(Cl)Cl,,,,test
US20050032786A1,CSc1cc(CCC(=O)OC(C)(C)C)cc(-c2nc(=O)c3ccccc3s2)n1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1cc(CCC(=O)OC(C)(C)C)cc(-c2nc(=O)c3ccccc3s2)n1,,ClC(Cl)Cl,,,,test
US20110257241A1,CC(C)(C)OC(=O)N1CCC(O)(c2cc(F)cc(F)c2)C1.CI>>COC1(c2cc(F)cc(F)c2)CCN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US05981559,CCOC(=O)COc1ccc(CCCS(=O)(=O)c2ccc(Cl)cc2)cc1NC(=O)c1ccc(C=Cc2nc3ccccc3s2)cc1>>O=C(O)COc1ccc(CCCS(=O)(=O)c2ccc(Cl)cc2)cc1NC(=O)c1ccc(C=Cc2nc3ccccc3s2)cc1,,C1CCOC1,,[Na+].[OH-],,test
US20110269738A1,CCOC(=O)CCN1CCC(=Cc2cccc(B3OC(C)(C)C(C)(C)O3)c2CC)CC1>>CCOC(=O)CCN1CCC(Cc2cccc(B3OC(C)(C)C(C)(C)O3)c2CC)CC1,[Pd],CCO,,,,test
US20080039509A1,NCc1ccc(C(=O)O)cc1.O=C(O)C=Cc1cccnc1>>O=C(C=Cc1cccnc1)NCc1ccc(C(=O)O)cc1,,C1CCOC1,,[Na+].[OH-],,test
US20130267729A1,CC(C)(C)OC(=O)NCC(=O)NCC(F)(F)F.Cl>>Cl.NCC(=O)NCC(F)(F)F,,ClCCl,O,O=C([O-])[O-].[Na+].[Na+],,test
US20110150864A1,CN1CCN(C2=NC(=O)C(=Cc3ccc4c(cnn4Cc4ccc(O)cc4C(F)(F)F)c3)S2)CC1.CS(=O)(=O)Cl>>CN1CCN(C2=NC(=O)C(=Cc3ccc4c(cnn4Cc4ccc(OS(C)(=O)=O)cc4C(F)(F)F)c3)S2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160038615A1,CC(=O)OC[C@H]1OC(O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OCc1ccccc1.O=P(Cl)(Oc1ccccc1)Oc1ccccc1>>CC(=O)OC[C@H]1O[C@H](OP(=O)(Oc2ccccc2)Oc2ccccc2)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OCc1ccccc1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN(CC)CC,O=C([O-])O.[Na+],test
US20130217680A1,CCOC(=O)Cc1cnc([N+](=O)[O-])cc1C>>CCOC(=O)Cc1cnc(N)cc1C,[Pd],CCO,,,,test
US20130338159A1,CSc1nccc(/C(=C/N(C)C)C(=O)CC2CC2)n1.N=CN>>CSc1nccc(-c2cncnc2CC2CC2)n1,,CN(C)C=O,,CC(=O)O,O=C([O-])[O-].[K+].[K+],test
US04956462,CC(=O)OCc1cc(Cl)n2nc(C)nc2n1.NC(N)=S>>Cc1nc2nc(CO)cc(S)n2n1,,CCO,,,,test
US20150376169A1,O=C1CCOc2cc(Br)ccc21.Sc1cccs1>>O=C1CCOc2cc(Sc3cccs3)ccc21,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04788195,ClCCN1CCOCC1.Nc1cccc(O)c1>>Nc1cccc(OCCN2CCOCC2)c1,,CN(C)C=O,,[H-].[Na+],,test
US20160039772A1,COc1ccc([N+](=O)[O-])c2c1C(c1ccc(Cl)cc1)OC2=O>>COc1ccc(N)c(C(=O)O)c1Cc1ccccc1,[Pd],CC(=O)O,,,,test
US20100113391A1,CCOC(=O)C(O)CCn1c(=O)c2cc(F)c(NC3CCCCC3)cc2n(C2CCCC2)c1=O.CI>>CCOC(=O)C(CCn1c(=O)c2cc(F)c(NC3CCCCC3)cc2n(C2CCCC2)c1=O)OC,O=[Ag],CN(C)C=O,,,,test
US20090023713A1,C=CCCNC(=O)C1(NC(=O)OC(C)(C)C)CC1.O=S(=O)(OCCOS(=O)(=O)C(F)(F)F)C(F)(F)F>>C=CCCN1CCN(C(=O)OC(C)(C)C)C2(CC2)C1=O,,C1CCOC1,,[H-].[Na+],,test
US20100173944A1,COc1ccnc(COC(C)=O)c1C>>COc1ccnc(CO)c1C,,Cc1ccccc1,,[Na+].[OH-],,test
US20030181468A1,Cc1sc2ncnc(N)c2c1-c1ccc([N+](=O)[O-])cc1.O=C1CCC(=O)N1Br>>Nc1ncnc2sc(CBr)c(-c3ccc([N+](=O)[O-])cc3)c12,,c1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20080004269A1,CCCc1c(Cc2ccnn2-c2ncccc2F)ncnc1C(C)=O.NC=O>>CCCc1c(Cc2ccnn2-c2ncccc2F)ncn2cnc(C)c12,,O,O=CO,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US20030171353A1,O=S(=O)(Cl)c1c(Cl)nc2sccn12.[N-]=[N+]=NCCCc1c[nH]c2ccc(F)cc12>>[N-]=[N+]=NCCCc1cn(S(=O)(=O)c2c(Cl)nc3sccn23)c2ccc(F)cc12,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20020082421A1,CC(C)Oc1ccccc1N1CCN(CCNC(=O)CN2CCCCC2=O)CC1.O=S(=O)(O)O>>CC(C)Oc1ccccc1N1CCN(CCNC(=O)CN2CCCCC2=O)CC1.O=S(=O)(O)O,,CCOC(C)=O,,CO,,test
US20160009744A1,Cc1sc(C=O)nc1CBr.OB(O)c1cccc(Cl)c1>>Cc1sc(C=O)nc1Cc1cccc(Cl)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20120046306A1,COc1cc(C#N)ccc1NC(=O)C/N=C/CC(C)(C)C.O=C1Nc2cc(F)cnc2/C1=C/c1cccc(Cl)c1F>>COc1cc(C#N)ccc1NC(=O)C1NC(CC(C)(C)C)C2(C(=O)Nc3cc(F)cnc32)C1c1cccc(Cl)c1F,,C1CCOC1,,[Li+].[OH-],,test
US20120115884A1,Clc1cnc(Cl)nc1.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2ncc(Cl)cn2)cc1,,CCO,Cc1ccccc1,,,test
US04870091,CCOC(=O)CC(=O)CCl.O=C1c2ccccc2C(=O)N1CCOCCO>>CCOC(=O)CC(=O)COCCOCCN1C(=O)c2ccccc2C1=O,,C1CCOC1,,Cl,[H-].[Na+],test
US05145958,CCOC(=O)c1cc(Cl)c(N)c(Cl)c1>>Nc1c(Cl)cccc1Cl,,O,,,,test
US20110301161A1,COC(=O)c1cc(F)ccc1C(=O)NC(=O)OC(C)(C)C>>COC(=O)c1cc(F)ccc1C(N)=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110200586A1,CC(Br)C(N)=O.CN(C1=NC(=O)C(=Cc2ccc3c(cnn3Cc3ccc(C(F)(F)F)cc3C(F)(F)F)c2)S1)C1CCNCC1>>CC(C(N)=O)N1CCC(N(C)C2=NC(=O)C(=Cc3ccc4c(cnn4Cc4ccc(C(F)(F)F)cc4C(F)(F)F)c3)S2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130336921A1,O=[N+]([O-])c1ccn(-c2cccc(C(F)(F)F)c2)n1>>Nc1ccn(-c2cccc(C(F)(F)F)c2)n1,[Pd],CO,,,,test
US05683623,Brc1ccc(I)cc1.CCCCCCCCCOc1ccc(B(O)O)c(F)c1F>>CCCCCCCCCOc1ccc(-c2ccc(Br)cc2)c(F)c1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US03989749,CCCCCC(CCCNC#N)OC(C)=O.CCOC(=O)C(C)CCCCCBr>>CCCCCC(CCCN(C#N)CCCCCC(C)C(=O)OCC)OC(C)=O,,c1ccccc1,,O,[H-].[Na+],test
US04246429,CC(N)c1ccccc1.O=C(O)C(Nc1ccc2ccccc2c1)c1c(Cl)cccc1Cl>>CC(N)c1ccccc1.O=C(O)C(Nc1ccc2ccccc2c1)c1c(Cl)cccc1Cl,,CCOCC,,,,test
US20160159755A1,CCc1cc(O)ccc1Br.Cc1cccc(-n2nnn(C)c2=O)c1CBr>>CCc1cc(OCc2c(C)cccc2-n2nnn(C)c2=O)ccc1Br,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20120277423A1,C=O.CC(=O)c1ccsc1.NCCc1ccccc1>>O=C(CCNCCc1ccccc1)c1ccsc1,,C1COCCO1,,,,test
US20040235822A1,Cc1ccnc(C(=O)c2ccc(F)cc2C(F)(F)F)c1.[N-]=[N+]=[N-]>>Cc1ccnc(C(O)c2ccc(N)cc2C(F)(F)F)c1,,CS(C)=O,,O,,test
US20060160865A1,CN(C(=O)Oc1ccc(N)cn1)c1ccccc1.O=C(Cl)c1ccccc1OC(F)(F)F>>CN(C(=O)Oc1ccc(NC(=O)c2ccccc2OC(F)(F)F)cn1)c1ccccc1,,CC#N,,CCN(CC)CC,ClCCl,test
US20150274663A1,CCOC(=O)CCN1CC=C(c2ccc(O[C@@H]3CC[C@@H](CC)CC3)cc2)CC1>>CCOC(=O)CCN1CCC(c2ccc(O[C@@H]3CC[C@@H](CC)CC3)cc2)CC1,[Pd],CO,,,,test
US04127720,COc1cc2c(cc1OC)-c1ncc(C(N)=O)c(=O)n1CC2>>COc1cc2c(cc1OC)-c1ncc(C#N)c(=O)n1CC2,,CC(=O)O,,,,test
US04855323,C=CCc1cccc(C2CCCC2)c1OCc1ccccc1.O=C(OO)c1cccc(Cl)c1>>c1ccc(COc2c(CC3CO3)cccc2C2CCCC2)cc1,,ClCCl,,,,test
US05023364,CCCc1c(OCc2ccccc2)ccc(C(C)=O)c1O.CCOC(=O)CCCBr>>CCCc1c(OCc2ccccc2)ccc(C(C)=O)c1OCCCC(=O)OCC,,CN(C)C=O,,[I-].[K+],,test
US20150031685A1,BOC([C@@H](N)c1ccccc1)N1CCCC1>>N[C@H](CN1CCCC1)c1ccccc1,,Cl,,,,test
US06048842,CCc1cc(OC)cc(OC)c1>>CCc1cc(O)cc(O)c1,,CC(=O)O,,Br,,test
US20040043999A1,COc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1OC1CCCC1.O=C(OO)c1cccc(Cl)c1>>COc1ccc2c(Cc3c(Cl)cncc3Cl)n[n+]([O-])cc2c1OC1CCCC1,,ClCCl,,,,test
US20020049223A1,CC(C)(C#N)c1cccs1>>CC(C)(CN)c1cccs1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100256097A1,C1COCCN1.FCC(Br)c1cccc(Br)n1>>FCC(c1cccc(Br)n1)N1CCOCC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US05089050,CC(=O)Oc1ccc(C(=O)O)cc1C(C)(C)C>>CC(C)(C)c1cc(C(=O)O)ccc1O,,CO,O,[Na+].[OH-],,test
US04476132,CCCC(=O)c1cc(C(=O)OCC)c(N(CC)C(=O)CC(=O)OCC)cc1C>>CCCC(=O)c1cc2c(O)c(C(=O)OCC)c(=O)n(CC)c2cc1C,,CCO,,Cl,[Na],test
US20020119983A1,O=CCCc1cc(-c2cccc([N+](=O)[O-])c2)no1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>O=[N+]([O-])c1cccc(-c2cc(CCCN3CCN(C(c4ccccc4)c4ccccc4)CC3)on2)c1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100324041A1,CC(C)N(C[C@@H](C(=O)N1CCN(c2c(-c3cccnc3)cnc3[nH]ccc23)CC1)c1ccc(Cl)cc1)C(=O)OC(C)(C)C>>CC(C)NC[C@@H](C(=O)N1CCN(c2c(-c3cccnc3)cnc3[nH]ccc23)CC1)c1ccc(Cl)cc1,,O=C(O)C(F)(F)F,,,,test
US05716964,Cc1nc(N2C(=O)c3ccccc3C2=O)ccc1Cl.O=C1CCC(=O)N1Br>>O=C1c2ccccc2C(=O)N1c1ccc(Cl)c(CBr)n1,,ClCCl,,,,test
US20050075363A1,Cc1cccc(C)[n+]1[O-].O=[N+]([O-])O>>Cc1cc([N+](=O)[O-])cc(C)[n+]1[O-],,O=S(=O)(O)O,,,,test
US20070105842A1,CC(C)(C)OC(=O)N1CCCN(c2ncccc2CNc2nncn2-c2cccc(Cl)c2Cl)CC1>>Clc1cccc(-n2cnnc2NCc2cccnc2N2CCCNCC2)c1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030186987A1,CN.Fc1cc2ncnc(Nc3cccc(Br)c3)c2cn1>>CNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1,,CC(C)O,,CCN(CC)CC,Cl,test
US20100216799A1,CC(C)(C)N(CCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O)C(=O)[O-]>>NCCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O,,C1COCCO1,,Cl,,test
US20120040953A1,CC(C)(C)OC(=O)N1CCC(OCC(=O)O)CC1.COc1ncc(C(=N)NO)cn1>>COc1ncc(-c2noc(COC3CCN(C(=O)OC(C)(C)C)CC3)n2)cn1,,C1CCOC1,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20160235734A1,O=C(O[C@@H]1CN2CCC1CC2)[C@@](O)(c1ccccc1)c1cccc(O)c1>>O=C(O)[C@](O)(c1ccccc1)c1cccc(O)c1,,CO,,[Na+].[OH-],,test
US20090143353A1,CN(C)[C@H]1CCNC1.Cc1c(-c2ccccc2)c(F)c2oc(N3CC(C)(O)C3)nc2c1C#N>>Cc1c(-c2ccccc2)c(N2CC[C@H](N(C)C)C2)c2oc(N3CC(C)(O)C3)nc2c1C#N,,CS(C)=O,,CCN(CC)CC,,test
US04629732,CC(C)(SC(F)(F)F)C(=O)CBr.Oc1ccc(Cl)cc1>>CC(C)(SC(F)(F)F)C(=O)COc1ccc(Cl)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090156610A1,CC(C)(C)OC(=O)N1CCC(CBr)CC1.O=Cc1cc(I)ccc1O>>CC(C)(C)OC(=O)N1CCC(COc2ccc(I)cc2C=O)CC1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US06762315B1,CCCCCOc1ccc(B(O)O)cc1.COC(=O)c1ccc(-c2ccc(I)cc2)cc1>>CCCCCOc1ccc(-c2ccc(-c3ccc(C(=O)OC)cc3)cc2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20110301142A1,COC(=O)Cc1ccc(O)cc1.Cc1noc(-c2ccc(CCl)cc2)c1NC(=O)O[C@H](C)c1ccccc1Cl>>COC(=O)Cc1ccc(OCc2ccc(-c3onc(C)c3NC(=O)O[C@H](C)c3ccccc3Cl)cc2)cc1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150376225A1,CC1([C@H]2CC[C@H]3[C@@H]4CCC5CC6(CC[C@]5(C)[C@H]4[C@@H](O)C[C@@]32C)OCCO6)OCCO1>>CC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4CC5(CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C)OCCO5,,CC(C)=O,O,O=S(=O)(O)O,,test
US06432993B1,CC(=O)OC(C)=O.Cc1cc(Oc2ccc3nc(COc4ccc(CC5SC(=O)NC5=O)cc4)n(C)c3c2)cc(C)c1N.Cl>>CC(=O)Nc1c(C)cc(Oc2ccc3nc(COc4ccc(CC5SC(=O)NC5=O)cc4)n(C)c3c2)cc1C.Cl,CN(C)c1ccncc1,C1CCOC1,,Cl,c1ccncc1,test
US20020019429A1,CNC(=O)[C@@H](NC(=O)[C@@H](CC(=O)OCc1ccccc1)c1ccn(-c2ccc(-c3ccc(C#N)cc3)cc2)c1)C(C)(C)C>>CNC(=O)[C@@H](NC(=O)[C@@H](CC(=O)O)c1ccn(-c2ccc(-c3ccc(C#N)cc3)cc2)c1)C(C)(C)C,,CCO,CCOC(C)=O,,,test
US20050107409A1,CC(C)(C)OC(=O)NCC1CCCN(C(=O)c2ccc3c(Cl)ncnc3c2)C1.N=C(N)c1cccc(CN)c1>>N=C(N)c1cccc(CNc2ncnc3cc(C(=O)N4CCCC(CN)C4)ccc23)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US04029787,CCOC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1.CN1CCNCC1>>CCOC(=O)c1ccc(N2CCN(C)CC2)c(S(N)(=O)=O)c1,,O,,,,test
US20060160840A1,COc1cc2c(cc1OC)CN(C(=O)Nc1ccc(Cl)cc1)[C@H](C(=O)O)C2.NC1=CCC(=NN2CCCC2)C=C1>>COc1cc2c(cc1OC)CN(C(=O)Nc1ccc(Cl)cc1)[C@H](C(=O)NC1=CCC(=NN3CCCC3)C=C1)C2,,CN(C)C=O,O,ClCCCl,,test
US20110015196A1,C=C(C)[C@@H]1CC[C@]2(C(=O)N3CCC(CC)(C(=O)O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CC1(C)CC(=O)OC1=O>>C=C(C)[C@@H]1CC[C@]2(C(=O)N3CCC(CC)(C(=O)O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(=O)CC(C)(C)C(=O)O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,CCOC(C)=O,,c1ccncc1,,test
US20080280836A1,C=CCOc1cc(Br)ccc1C=O.Nc1ccc(O)cc1>>C=CCOc1cc(Br)ccc1/C=N/c1ccc(O)cc1,,CC(C)O,,,,test
US20100292208A1,Clc1nc2ccccc2s1.OCCc1coc2cc(O)ccc12>>OCCc1coc2cc(Oc3nc4ccccc4s3)ccc12,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070155764A1,CC(C)(C)OC(=O)Nc1ccc(Oc2ccnc(-n3cncn3)n2)cc1>>Nc1ccc(Oc2ccnc(-n3cncn3)n2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140175402A1,C1=Cc2ccc3c([nH]c4ccccc43)c2CC1>>c1ccc2c(c1)ccc1c3ccccc3[nH]c21,,c1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20140206681A1,CC1(C)OB(c2ccc(C(=O)Nc3cc(C(F)(F)F)ccn3)cc2OCc2ccccc2)OC1(C)C>>CC1(C)OB(c2ccc(C(=O)Nc3cc(C(F)(F)F)ccn3)cc2O)OC1(C)C,[Pd],CCOC(C)=O,,CO,,test
US20120115850A1,NCc1cccc(Cl)c1.O=[N+]([O-])c1ccc(F)cc1F>>O=[N+]([O-])c1ccc(F)cc1NCc1cccc(Cl)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20030060460A1,CC(=O)OC(C)=O.COc1cc(C(C)(C)O)ccc1NS(=O)(=O)c1ccccc1>>COc1cc(C(C)(C)O)ccc1N(C(C)=O)S(=O)(=O)c1ccccc1,,CCN(CC)CC,ClCCl,,,test
US06207686B1,CCOC(=O)C(c1ccc2c(c1)OCO2)C(O)C1CCCCC1>>O=C(O)C(c1ccc2c(c1)OCO2)C(O)C1CCCCC1,,CCO,,[Na+].[OH-],,test
US04161599,O=NN1Cc2sccc2C(O)C1C(=O)O>>O=C(O)c1cc2ccsc2cn1,,CCO,,[Na+].[OH-],,test
US20110092485A1,CC1(C)OB(c2ccc(CC(=O)OCCF)cc2)OC1(C)C.CCCN(CCCO[Si](C)(C)C(C)(C)C)C(=O)C1=Cc2ccc(Br)cc2N=C(NC(=O)OC(C)(C)C)C1>>CCCN(CCCO[Si](C)(C)C(C)(C)C)C(=O)C1=Cc2ccc(-c3ccc(CC(=O)OCCF)cc3)cc2N=C(NC(=O)OC(C)(C)C)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20060160851A1,CCOC(=O)c1cccc(O)c1.O=C(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)N1CCC(O)CC1>>CCOC(=O)c1cccc(OC2CCN(C(=O)Oc3ccc(Oc4ccc(C(F)(F)F)cn4)cc3)CC2)c1,,CCOC(C)=O,,,,test
US20060293299A1,CC(C)(C#N)C(O)(c1cc(F)cc(F)c1)C1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1>>CC(C)(C#N)C(=C1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1)c1cc(F)cc(F)c1,,c1ccncc1,,O=P(Cl)(Cl)Cl,,test
US20140343035A1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)C1.COc1cc(C#Cc2n[nH]c3ncnc(N)c23)cc(OC)c1>>COc1cc(C#Cc2nn(C3CCN(C(=O)OC(C)(C)C)C3)c3ncnc(N)c23)cc(OC)c1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120035134A1,O=C1C[C@@H](NC(=O)OCc2ccccc2)C(=O)O1>>O=C(O)C[C@H](CO)NC(=O)OCc1ccccc1,,C1CCOC1,,[BH4-].[Na+],,test
US20120277224A1,CCOC(=O)CC(=O)c1ccc2c(c1)OCO2.Cc1n[nH]c(N)c1Cc1cccc(Cl)c1>>Cc1nn2c(=O)cc(-c3ccc4c(c3)OCO4)[nH]c2c1Cc1cccc(Cl)c1,,CC(=O)O,,,,test
US20040121965A1,CC(=O)NCC(=O)O.O=Cc1cccs1>>CC1=N/C(=C\c2cccs2)C(=O)O1,,CC(=O)OC(C)=O,,CC(=O)[O-].[Na+],,test
US20110319378A1,CI.COc1ccc(CN2C(=O)CC[C@H](c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)c(OC)c1>>COc1ccc(CN2C(=O)C(C)C[C@H](c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)c(OC)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20110195954A1,O=C(c1cc(Cl)ncn1)N1CCc2ccccc21.O=C1Nc2ccc(Cl)cc2CCN1C1CCNCC1>>O=C(c1cc(N2CCC(N3CCc4cc(Cl)ccc4NC3=O)CC2)ncn1)N1CCc2ccccc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20130224186A1,CC(=O)O[C@@H](C)C(=O)Cl.CC(C)(C)[C@@H](NC[C@@H]1CN(C(=O)OCc2ccccc2)C[C@@H]1F)c1nc(-c2cc(F)ccc2F)sc1Cc1ccccc1>>CC(=O)O[C@@H](C)C(=O)N(C[C@@H]1CN(C(=O)OCc2ccccc2)C[C@@H]1F)[C@@H](c1nc(-c2cc(F)ccc2F)sc1Cc1ccccc1)C(C)(C)C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05656636,COc1ccc(CCCCCCCCOc2ccc(C)nc2/C=C/CC(=O)O)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(CCCCCCCCOc2ccc(C)[n+]([O-])c2/C=C/CC(=O)O)cc1,,ClCCl,,,,test
US05104888,C=CC(=O)OCC.CC(=O)Oc1c(C)c(C)c2c(c1C)C(=O)CC(O)(COc1ccc(N)cc1)O2.Cl>>CCOC(=O)C(Cl)Cc1ccc(OCC2(O)CC(=O)c3c(C)c(OC(C)=O)c(C)c(C)c3O2)cc1,,CC(C)=O,O,O=N[O-].[Na+],,test
US04049812,CCOC(=O)c1nc(CCl)n(-c2ccccc2C(=O)c2ccccn2)n1>>O=C(O)c1nc(CCl)n(-c2ccccc2C(=O)c2ccccn2)n1,,CCO,,[Na+].[OH-],,test
US20110201604A1,CCNc1ccc(C(=O)OC)cc1N.Nc1nc2ccc(OC(F)(F)F)cc2s1.S=C(n1ccnc1)n1ccnc1>>CCn1c(Nc2nc3ccc(OC(F)(F)F)cc3s2)nc2cc(C(=O)OC)ccc21,,ClCCCl,,,,test
US07049312B1,O=C1Nc2ccc([N+](=O)[O-])cc2SC1=Cc1c[nH]c2ccccc12>>Nc1ccc2c(c1)SC(=Cc1c[nH]c3ccccc13)C(=O)N2,[Ni],CCO,,NN,O,test
US20100121048A1,CCOC(=O)c1cc[nH]c1C.O=[N+]([O-])c1ccc(F)cc1>>CCOC(=O)c1ccn(-c2ccc([N+](=O)[O-])cc2)c1C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130237535A1,CC1(NCC2(O)CCN(C(=O)OC(C)(C)C)CC2)CC1.O=C(Cl)CCl>>CC(C)(C)OC(=O)N1CCC(O)(CN(C(=O)CCl)C2(C)CC2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120316161A1,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1Cl.OB(O)c1ccc2c(c1)OCCCO2>>CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc2c(c1)OCCCO2,,COCCOC,O,CCN(C(C)C)C(C)C,,test
US20070082907A1,O=C(O)c1ccc(C(F)(F)F)cc1F.Oc1ccccc1>>O=C(O)c1ccc(C(F)(F)F)cc1Oc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110201593A1,CC1(N)CCN(C(=O)OC(C)(C)C)CC1.O=[N+]([O-])c1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1Cl>>CC1(Nc2c([N+](=O)[O-])cnc3c2ccn3S(=O)(=O)c2ccccc2)CCN(C(=O)OC(C)(C)C)CC1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US04029491,C=CCNCC=O.O=C=Nc1nc2ccc(Cl)cc2s1>>C=CCN(CC=O)C(=O)Nc1nc2ccc(Cl)cc2s1,,c1ccccc1,,,,test
US20120232056A1,Brc1ccccn1.C[C@H]1CNCCN1C(=O)OC(C)(C)C>>C[C@H]1CN(c2ccccn2)CCN1C(=O)OC(C)(C)C,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US20090093454A1,CC(C)(C)OC(=O)n1c(CN2CCC[C@@H]3CCc4cccnc4[C@H]32)nc2ccccc21>>c1cnc2c(c1)CC[C@H]1CCCN(Cc3nc4ccccc4[nH]3)[C@H]21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140051692A1,COC(=O)CC(C(C)=O)C(=O)OC.Nc1cc(-c2cccc(Br)c2)n[nH]1>>COC(=O)Cc1c(C)nc2cc(-c3cccc(Br)c3)nn2c1O,,Cc1ccccc1C,,,,test
US05994368,Cc1ccc([N+](=O)[O-])c(C)c1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>Cc1ccc(N)c(C)c1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,[Fe],CCO,,O,[Cl-].[NH4+],test
US20040209886A1,CNOC.Cc1c(C(=O)Cl)cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c12>>CON(C)C(=O)c1cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c2c1C,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,Cl,test
US20040171606A1,CC1(C)COC(CCCBr)OC1.Cn1c(S)nnc1-c1ccc2ncccc2c1>>Cn1c(SCCCC2OCC(C)(C)CO2)nnc1-c1ccc2ncccc2c1,,CN(C)C=O,,[Li+].[OH-],,test
US20080096874A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](c2ccc(NC(=O)OCc3ccccc3)cc2)CC1>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](c2ccc(N)cc2)CC1,[Pd],CCO,CCOC(C)=O,,,test
US20090203692A1,CN(C)C=O.COc1cccc(B(O)O)n1.O=C1N=C(Nc2cc(Br)ccc2Cl)S/C1=C\c1ccc2ccccc2c1>>COc1cccc(-c2ccc(Cl)c(NC3=NC(=O)/C(=C/c4ccc5ncccc5c4)S3)c2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20160083379A1,CI.COc1ccc(Nc2ccccn2)cc1>>COc1ccc(N(C)c2ccccn2)cc1,,CN(C)C=O,O,CC(C)(C)[O-].[K+],,test
US20110183956A1,O=C1OC[C@H](c2ccccc2)N1C(=O)[C@H](C/C=C\c1ccc(F)cc1)[C@H](Nc1ccc(F)cc1)c1ccc(OCc2ccccc2)cc1>>O=C1[C@H](C/C=C\c2ccc(F)cc2)[C@@H](c2ccc(OCc3ccccc3)cc2)N1c1ccc(F)cc1,,Cc1ccccc1,,,,test
US20090029994A1,CCN(CCC(=O)OC(C)(C)C)C(=O)c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(N2CCOCC2)cn1>>CCN(CCC(=O)O)C(=O)c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(N2CCOCC2)cn1,,CCOC(C)=O,Cl,O=C([O-])O.[Na+],,test
US04144338,CN(C)C(=O)Cl.Cc1cc(C)nc(NCCN(C(C)C)C(C)C)n1>>Cc1cc(C)nc(N(CCN(C(C)C)C(C)C)C(=O)N(C)C)n1,,CCO,Cc1ccccc1,[Na+].[OH-],,test
US20140018313A1,CCC(=O)Cl.COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc3cc(-c4ccc(-c5cnc(C6CCCN6C(=O)C(N)c6ccccc6)[nH]5)cc4)ccc3c2)[nH]1)C(C)C>>CCC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(-c3ccc4cc(-c5cnc(C6CCCN6C(=O)C(NC(=O)OC)C(C)C)[nH]5)ccc4c3)cc2)[nH]1)c1ccccc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090247746A1,CCOCCN(c1cccc2cc(C(N)=O)[nH]c12)S(=O)(=O)c1cccs1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOCCN(c1cccc2cc(C(N)=S)[nH]c12)S(=O)(=O)c1cccs1,,C1CCOC1,,,,test
US20100009986A1,CN(C)C1(Cc2ccccc2)CC=C(c2[nH]c3ccccc3c2C2CC2)CC1>>CN(C)C1(Cc2ccccc2)CCC(c2[nH]c3ccccc3c2C2CC2)CC1,[Pd],CO,,Cl,,test
US20130217664A1,CCN.COc1cc(Cl)ncc1[N+](=O)[O-]>>CCNc1cc(Cl)ncc1[N+](=O)[O-],,C1CCOC1,O,,,test
US20090298823A1,CS(=O)O[Na].O=[N+]([O-])c1cccc(CBr)c1>>CS(=O)(=O)Cc1cccc([N+](=O)[O-])c1,,CCO,,,,test
US20160002225A1,O=P(Cl)(Cl)Cl.[O-][n+]1cccc2cn[nH]c21>>Clc1ccnc2[nH]ncc12,,CC#N,,,,test
US04310545,O=C(O)c1ccc(NCCCCCCCCCCCCCCCC(F)(F)F)cc1.OCC(O)CI>>O=C(OCC(O)CO)c1ccc(NCCCCCCCCCCCCCCCC(F)(F)F)cc1,,O,,CCOCC,[Na+].[OH-],test
US05132435,ClCc1ccccc1Cl.c1cc2c(s1)CCNC2>>Cl.Clc1ccccc1CN1CCc2sccc2C1,,CCO,,O=C([O-])O.[Na+],,test
US20130116235A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1nc2cnccn2n1>>CC(C)(C)OC(=O)Nc1nc2cnccn2n1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20120208815A1,CC(C)(C)OC(=O)N1C(=O)O[C@H]2CCN(c3ccncc3N)C[C@H]21.CC(C)NC(=O)c1ccc(F)c(-c2ccc(N)c(C(=O)O)n2)c1>>CC(C)NC(=O)c1ccc(F)c(-c2ccc(N)c(C(=O)Nc3cnccc3N3CC[C@@H]4OC(=O)N(C(=O)OC(C)(C)C)[C@@H]4C3)n2)c1,,CN(C)C=O,O,ClCCCl,On1nnc2cccnc21,test
US20040116471A1,BrCc1ccco1.CCOC(=O)N1CCC(c2c[nH]c3cc(F)ccc23)CC1>>CCOC(=O)N1CCC(c2cn(Cc3ccco3)c3cc(F)ccc23)CC1,,CCOCC,,,,test
US20050020503A1,Br.Nc1c(O)cccc1[N+](=O)[O-]>>O=[N+]([O-])c1cccc(O)c1Br,,C1COCCO1,O,O=N[O-].[Na+],,test
US20110142826A1,COC(=O)c1cc2ccncn2c1Nc1ccc(I)cc1F.O=C1CCC(=O)N1Cl>>COC(=O)c1c(Cl)c2ccncn2c1Nc1ccc(I)cc1F,,ClCCl,O,,,test
US20110269956A1,CC(C)(C)OC(=O)N1[C@@H]2C[C@@H]2C[C@H]1c1ncc(I)[nH]1>>Ic1cnc([C@@H]2C[C@H]3C[C@H]3N2)[nH]1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06011028,Nc1cccc(Cc2ccccc2)n1>>N=C1CCCC(Cc2ccccc2)N1,[Rh],CC(=O)O,,,,test
US04723002,CCOC(=O)/C=C/c1cc(=O)c(OCc2ccccc2)c[nH]1>>O=C(O)/C=C/c1cc(=O)c(OCc2ccccc2)c[nH]1,,CCO,,[K+].[OH-],,test
US20040158065A1,C=CC(=O)Cl.CC(=O)N(c1ccc(F)c(Cl)c1)c1ncnc2cc(OCCCN3CCOCC3)c(N)cc12>>C=CC(=O)Nc1cc2c(N(C(C)=O)c3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCOCC1,,C1CCOC1,,CCN(CC)CC,,test
US20140135332A1,CC1(C)OCC(CC(N)=O)O1.O=C(CBr)c1ccc(C(F)(F)F)cc1>>CC1(C)OCC(Cc2nc(-c3ccc(C(F)(F)F)cc3)co2)O1,,O,,,,test
US20070287708A1,COc1ccc(Cn2cc(C#N)c(=O)c(-c3cccc(OCCCl)c3)c2)cc1OC.O=P(Cl)(Cl)Cl>>N#Cc1cncc(-c2cccc(OCCCl)c2)c1Cl,,O=P(Cl)(Cl)Cl,,[Cl-].[Li+],,test
US20030114437A1,O=C(N[C@@H](CC1CCCCC1)C(=O)NC1CCCN(S(=O)(=O)c2ccccn2)CC1O)c1cc2ccccc2o1>>O=C(N[C@@H](CC1CCCCC1)C(=O)NC1CCCN(S(=O)(=O)c2ccccn2)CC1=O)c1cc2ccccc2o1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20070142479A1,Cc1ccc(O)cc1.O=C(O)C=Cc1ccccc1>>Cc1ccc2c(c1)C(c1ccccc1)CC(=O)O2,,Cc1ccccc1,,O,,test
US04847289,C=O.CNC.NS(=O)(=O)c1ccc(S(=O)(=O)CCCc2ccc(O)cc2)s1>>CN(C)Cc1cc(CCCS(=O)(=O)c2ccc(S(N)(=O)=O)s2)ccc1O,,CCO,,CO,ClC(Cl)Cl,test
US20100087429A1,NC1=N[C@@]2(CO1)c1cc(O)ccc1Oc1ncc(C3=CCOCC3)cc12>>NC1=N[C@@]2(CO1)c1cc(O)ccc1Oc1ncc(C3CCOCC3)cc12,[Pd],CO,,,,test
US20070225300A1,CS(=O)(=O)Cl.OCC1Cc2nccnc2C1>>CS(=O)(=O)OCC1Cc2nccnc2C1,,ClCCl,O,CCN(CC)CC,,test
US20110021534A1,CCOC(Cc1ccc(OC(=O)Cc2ccc(NC(=O)OC(C)(C)C)cc2)c(C)c1)C(=O)OCc1ccccc1>>CCOC(Cc1ccc(OC(=O)Cc2ccc(NC(=O)OC(C)(C)C)cc2)c(C)c1)C(=O)O,,CCOC(C)=O,,CO,,test
US03998834,CCC(=O)N(c1ccccc1)C1(COC)CCN(C(C)C(=O)c2ccccc2)CC1>>CCC(=O)N(c1ccccc1)C1(COC)CCN(C(C)C(O)c2ccccc2)CC1,,CO,,[BH4-].[Na+],,test
US20130296327A1,COC(=O)C(Cc1nc2ccccc2s1)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NC(Cc1nc2ccccc2s1)C(=O)O,,CO,O,[Li+].[OH-],,test
US20100099681A1,COC(=O)c1ccccc1Nc1c(-c2cc(F)c3nccnc3c2)c(C)nn1-c1ccc(F)cc1F>>Cc1nn(-c2ccc(F)cc2F)c(Nc2ccccc2C(=O)O)c1-c1cc(F)c2nccnc2c1,,C1COCCO1,O,Cl,[Na+].[OH-],test
US20100305122A1,COC(=O)[C@@H]1CC(F)(F)CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1CC(F)(F)CN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04957914,CON1C=CC2=C3C(CCC2)CC(C)CC3C1>>CC1CC2CCCC3=C2C(C1)CN(O)C=C3,,ClCCl,,BrB(Br)Br,CO,test
US05179125,CC(=O)SCC(Cc1ccccc1)C(=O)Nc1cc(C)cc(C(=O)O)c1>>Cc1cc(NC(=O)C(CS)Cc2ccccc2)cc(C(=O)O)c1,,CO,,Cl,[Na+].[OH-],test
US20110136843A1,CCOC(=O)c1cc(Cl)c(OCc2ccc(OC)cc2)cc1O>>COc1ccc(COc2cc(O)c(C(=O)O)cc2Cl)cc1,,CCO,O,Cl,,test
US20090221555A1,CCN1CC(=O)Nc2cc(N)c(OC)cc2C1.CS(=O)(=O)N[C@@H]1CCCC[C@H]1Nc1nc(Cl)ncc1Cl>>CCN1CC(=O)Nc2cc(Nc3ncc(Cl)c(N[C@@H]4CCCC[C@H]4NS(C)(=O)=O)n3)c(OC)cc2C1,,CO,ClCCl,[NH4+].[OH-],,test
US20060160877A1,COCC(=O)O.Cl.Nc1cccc(-c2cccc3cc(C(=O)N[C@H]4CN5CCC4CC5)sc23)c1>>COCC(=O)Nc1cccc(-c2cccc3cc(C(=O)N[C@H]4CN5CCC4CC5)sc23)c1.Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070105838A1,N#Cc1ccc(F)cc1Cl.OCCCN1CCCCC1>>N#Cc1ccc(OCCCN2CCCCC2)cc1Cl,,CCOC(C)=O,CS(C)=O,[H-].[Na+],,test
US20070161640A1,N[C@@H](CC(=O)OCc1ccccc1)C(=O)OCc1ccccc1.O=Cc1ccccc1>>O=C(C[C@H](NCc1ccccc1)C(=O)OCc1ccccc1)OCc1ccccc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US05521192,CCCCCCCCCCC(O)c1cccc(OCc2ccccc2)c1>>CCCCCCCCCCCc1cccc(O)c1,[Pd],CC(=O)O,CCO,O,,test
US20100261702A1,BrBr.Cc1csc(C#N)c1>>Cc1cc(C#N)sc1Br,,CC(=O)O,,,,test
US20130331409A1,Brc1cccn2ccnc12.OB(O)c1ccc(O)cc1>>Oc1ccc(-c2cccn3ccnc23)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20150368273A1,CC(=O)O.COc1cnc2nc[nH]c2c1>>COC1CCc2nccn2C1,[Pd],,,,,test
US05021420,O=S1(=O)c2cccc3cccc(c23)N1CCCCl.c1ccc(C2(c3ccccc3)CCNCC2)cc1>>O=S1(=O)c2cccc3cccc(c23)N1CCCN1CCC(c2ccccc2)(c2ccccc2)CC1,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US20090054425A1,Cc1ccc(S(=O)(=O)n2ccc3c(Cl)nc(Cl)nc32)cc1.Nc1ccc2cn[nH]c2c1>>Cc1ccc(S(=O)(=O)n2ccc3c(Nc4ccc5nc[nH]c5c4)nc(Cl)nc32)cc1,,CCCCO,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US05059691,COC(OC)N(C)C.NC(=O)c1cnn2c(-c3ccccc3)ccnc12>>CN(C)C=NC(=O)c1cnn2c(-c3ccccc3)ccnc12,,ClCCl,,,,test
US20090170913A1,CCOC(=S)[S-].Nc1cc([N+](=O)[O-])ccc1O>>O=[N+]([O-])c1ccc2oc(=S)[nH]c2c1,,c1ccncc1,,Cl,,test
US20160168139A1,CCO.CCOC(OCC)OCC.O=C1CC(C(=O)O)C1>>CCOC(=O)C1CC(OCC)(OCC)C1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20060154928A1,CCCCCCCCCCCC=O.Cl.N=C(N)NC(=N)Nc1ccc(F)cc1F>>CCCCCCCCCCCC1N=C(N)N=C(N)N1c1ccc(F)cc1F.Cl,,CCO,,Cl,,test
US06117841,CC(=O)OCCBr.CNC(CC(C)C)C(=O)NC(Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(C)(C)C>>CCOC(=O)CN(C)C(CC(C)C)C(=O)NC(Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(C)(C)C,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20070093484A1,C#CC(C)O.[N-]=[N+]=NCc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1C(=O)NN1CCCCC1>>CC(O)c1cnnn1Cc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1C(=O)NN1CCCCC1,,Cc1ccccc1,,,,test
US20110218201A1,Cc1ccc(OCc2ccccc2)cc1C(=O)O.O=C(Cl)C(=O)Cl>>Cc1ccc(OCc2ccccc2)cc1C(=O)Cl,,ClCCl,,,,test
US20020052399A1,O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O.OCc1cccnc1>>O=C([O-])OCc1cccnc1.O=C1CCC(=O)N1O,,CC#N,,c1ccncc1,,test
US20150094328A1,Cc1cc(-c2ccc(C=O)c(F)c2)ccn1>>Cc1cc(-c2ccc(CO)c(F)c2)ccn1,,CO,,[BH4-].[Na+],,test
US20120283222A1,C=CS(=O)(=O)OC(C)C.CC(C)[Si](OCCCN)(C(C)C)C(C)C>>CC(C)OS(=O)(=O)CCNCCCO[Si](C(C)C)(C(C)C)C(C)C,,CO,,,,test
US20100179128A1,BrCCCc1ccccc1.CCCCn1c(=O)[nH]c(=O)c2c1ncn2Cc1ccccc1>>CCCCn1c(=O)n(CCCc2ccccc2)c(=O)c2c1ncn2Cc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100063066A1,COc1cnc(-c2oc3cnccc3c2O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)nc1>>COc1cnc(-c2oc3cnccc3c2O)nc1,,CCO,,CC(=O)O,[Na+].[OH-],test
US20070249670A1,Nc1cc(-c2cccnc2)sc1C(=O)O.O=C=Nc1c(Cl)cccc1Cl>>O=C(Nc1cc(-c2cccnc2)sc1C(=O)O)Nc1c(Cl)cccc1Cl,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20040229872A1,COC(=O)[C@@H](N)Cc1c[nH]c2cc(F)ccc12>>COC(=O)[C@@H](N)Cc1c[nH]c2cc(F)ccc12,,ClCCCl,,Cl,N,test
US20140045828A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1=N[C@@]2(COC1)c1cc(O)ccc1Oc1c(F)cc(C3=CCOCC3)cc12>>CC(C)(C)OC(=O)NC1=N[C@@]2(COC1)c1cc(O)ccc1Oc1c(F)cc(C3=CCOCC3)cc12,,C1CCOC1,,,,test
US04224242,CC(C)NCCCN.Cc1ccc(Cl)cc1N=C=O.ClCCl>>Cc1ccc(Cl)cc1NC(=O)NCCCNC(C)C.Cl,,ClCCl,,,,test
US06340678B1,Cc1ccc(S(=O)(=O)N2CCC(F)(F)/C(=C\C(=O)N3CCN(C)CC3)c3ccccc32)cc1>>CN1CCN(C(=O)/C=C2/c3ccccc3NCCC2(F)F)CC1,,O=S(=O)(O)O,,[Na+].[OH-],,test
US06593335B1,NC1=CC(=O)CCC1.O=C1CCS(=O)(=O)C1.O=Cc1ccc(C(F)(F)F)c([N+](=O)[O-])c1>>O=C1CCCC2=C1C(c1ccc(C(F)(F)F)c([N+](=O)[O-])c1)C1=C(CCS1(=O)=O)N2,,CCO,,CCN(CC)CC,,test
US04673676,CCOC(=O)c1cnc2c3cc(NC(=O)C(C)(C)C)ccc3c(C)cn2c1=O>>Cc1cn2c(=O)c(C(=O)O)cnc2c2cc(NC(=O)C(C)(C)C)ccc12,,CO,,[Na+].[OH-],,test
US20040010148A1,CC(=O)OC(C)=O.COc1ccc(F)cc1C(C)(C)CC(N)(Cc1ccnc2ccccc12)C(F)(F)F>>COc1ccc(F)cc1C(C)(C)CC(Cc1ccnc2ccccc12)(NC(C)=O)C(F)(F)F,,CC(Cl)Cl,,,,test
US20040259877A1,C[Si](C)(C)C#Cc1ccc(O)c(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1>>C#Cc1ccc(O)c(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1,,CO,,Cl,[Na+].[OH-],test
US20070225377A1,CCC(CC)(c1ccc(C#CC(O)C(C)(C)C)c(C)c1)c1ccc(O[Si](C)(C)C(C)(C)C)c(C)c1>>CCC(CC)(c1ccc(/C=C/C(O)C(C)(C)C)c(C)c1)c1ccc(O[Si](C)(C)C(C)(C)C)c(C)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20030171339A1,Nc1ccc(O)cc1O.O=C(Cl)OCc1ccccc1>>O=C(Nc1ccc(O)cc1O)OCc1ccccc1,,O,,Cl,[Na+].[OH-],test
US05567698,O=S(Cl)Cl.OC(=S)Cc1cc(Cl)ccc1Cl>>S=C(Cl)Cc1cc(Cl)ccc1Cl,,ClCCl,,,,test
US20110230458A1,CC(C)(C)OC(=O)N1CCC(Oc2cc(-c3ccc(OC4CCCCC4)cc3)c(C3CCC3)nn2)CC1.Cl.ClCCl>>Cl.Cl.c1cc(-c2cc(OC3CCNCC3)nnc2C2CCC2)ccc1OC1CCCCC1,,C1COCCO1,ClCCl,,,test
US20060173018A1,CC(C)C[C@@H](O)C(=O)N1CCNCC1.Oc1ccccc1-c1nc(Cl)c2cc(Br)ccc2n1>>CC(C)C[C@@H](O)C(=O)N1CCN(c2nc(-c3ccccc3O)nc3ccc(Br)cc23)CC1,,ClCCl,,CCN(CC)CC,,test
US20100324030A1,CCOC(=O)CCl.O=Cc1ccc([N+](=O)[O-])c(O)c1>>CCOC(=O)COc1cc(C=O)ccc1[N+](=O)[O-],,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05268391,C#CC[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C>>C#CC[C@H](O)[C@H](O)[C@@H](N)CC1CCCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130225524A1,CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(Br)ccc23)c1.Cc1ncc(B(O)O)n1C>>CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(-c4cnc(C)n4C)ccc23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CS(C)=O,,,,test
US20080044379A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=C(OCc1ccccc1)[C@@H](O)c1ccccc1>>Cc1ccc(S(=O)(=O)OC(C(=O)OCc2ccccc2)c2ccccc2)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20120015957A1,CC(C)(C)OC(=O)N1CCNCC1.N#Cc1ccc(F)c(Br)c1>>CC(C)(C)OC(=O)N1CCN(c2ccc(C#N)cc2Br)CC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US05292739,COc1ccccc1N1CCN(CCC(=O)Nc2cc(C)nn2C)CC1>>COc1ccccc1N1CCN(CCCNc2cc(C)nn2C)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140274702A1,Nc1cc(Cl)c(Br)cc1[N+](=O)[O-]>>[O-][n+]1onc2cc(Cl)c(Br)cc21,,CCO,,[K+].[OH-],,test
US20090209524A1,CCCC/C=C/C(=O)OC(C)(C)C.C[C@H](NCc1ccccc1)c1ccccc1>>CCCC[C@@H](CC(=O)OC(C)(C)C)N(Cc1ccccc1)[C@@H](C)c1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US20130178499A1,Nc1ccc(O)cc1F.O=C(Cl)CCCl>>O=C(CCCl)Nc1ccc(O)cc1F,,CC(C)=O,,,,test
US20060025433A1,CCN(C(C)C)C(C)C.CCOC(C)=O.CN(C)C=O.FC(F)(F)Oc1ccccc1CNc1ncc(C(F)(F)F)c(Cl)n1>>N[C@@H]1CC[C@@H](CNc2nc(NCc3ccccc3OC(F)(F)F)ncc2C(F)(F)F)CC1,,CCOC(C)=O,CN(C)C=O,,,test
US20090286791A1,BrC1CCCCC1.CCOc1ccc(C(=O)NCCNC(=O)c2c[nH]nc2C(F)(F)F)cc1>>CCOc1ccc(C(=O)NCCNC(=O)c2cn(C3CCCCC3)nc2C(F)(F)F)cc1,,CCOC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090143361A1,COc1ccc2nc(C#N)c3c(C)ncn3c2n1.O=C1CCC(=O)N1Br>>COc1ccc2nc(C#N)c3c(C)nc(Br)n3c2n1,,CC#N,,,,test
US20050261245A1,CCI.CS(=O)(=O)c1ccc(/C(COC(=O)OCCCCBr)=C(/C(=O)O)c2ccccc2)cc1>>CCOC(=O)/C(=C(\COC(=O)OCCCCBr)c1ccc(S(C)(=O)=O)cc1)c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080119447A1,C=O.C[C@]12C(=CC[C@@H]3[C@@H]1CC[C@]1(C)C(=O)CC[C@@H]31)C=C(N1CCCC1)CC2N1CCCC1.O=S(=O)(O)O>>C[C@]12C=CC(=O)C=C1C(CO)C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12,,ClCCl,,,,test
US08129361B2,COc1cccc(CCCO)c1.O=C1CCC(=O)N1Br>>COc1cccc(CCCBr)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20030078251A1,CCOC(=O)c1oc2ccc(NC(=O)C[C@H]3O[C@H](c4cccc(OC)c4OC)c4cc(Cl)ccc4N(CC(C)(C)COC(C)=O)C3=O)cc2c1C>>COc1cccc([C@H]2O[C@H](CC(=O)Nc3ccc4oc(C(=O)O)c(C)c4c3)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US05189179,COc1ccc(NC(=O)CCCCC(=O)N(C)OC)cc1.Cl[Mg]Cc1ccccc1>>COc1ccc(NC(=O)CCCCC(=O)Cc2ccccc2)cc1,,C1CCOC1,,Cl,,test
US20070105904A1,C#Cc1ccc(COC)nc1N.ON=C(Cl)Cc1ccc(Cc2ccc(Cl)o2)cc1>>COCc1ccc(-c2cc(Cc3ccc(Cc4ccc(Cl)o4)cc3)no2)c(N)n1,,O,,C1CCOC1,CCN(CC)CC,test
US20060142265A1,CN.Cc1c(C=O)sc2ccc(Cl)cc12>>CNCc1sc2ccc(Cl)cc2c1C,,CO,,[BH4-].[Na+],,test
US20150291586A1,CC(C)Cn1cc2c(cc1=O)C(C)(C)C(=O)N2C(=O)OC(C)(C)C>>CC(C)Cn1cc2c(cc1=O)C(C)(C)C(=O)N2,,CCOC(C)=O,,Cl,,test
US05189054,CCOC(=O)c1c(NCCC(=O)c2ccc(C(F)(F)F)cc2)c2c(Cl)cc(Cl)cc2n1C(=O)OC(C)(C)C>>CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1NCCC(=O)c1ccc(C(F)(F)F)cc1,,CCOC(C)=O,ClCCl,O=C(O)C(F)(F)F,,test
US20110190309A1,O=C(CBr)Nc1cnccn1.O=C(O[C@H]1CN2CCC1CC2)C1(c2ccccc2)CCCCCC1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C1(c3ccccc3)CCCCCC1)C2)Nc1cnccn1.[Br-],,CC#N,,,,test
US20120214854A1,CCOC(=O)C(=O)NCC(=O)c1ccc([N+](=O)[O-])cc1>>CCOC(=O)c1ncc(-c2ccc([N+](=O)[O-])cc2)o1,,O=P(Cl)(Cl)Cl,,,,test
US20110301122A1,CN.Cc1cc(-c2nc(-c3ccc(C4(CO)CCOCC4)cc3)no2)nn1Cc1ccc(Cl)nc1>>CNc1ccc(Cn2nc(-c3nc(-c4ccc(C5(CO)CCOCC5)cc4)no3)cc2C)cn1,,CCO,,,,test
US20100075948A1,CC(C)(C)OC(=O)CN.CC(C)C(C)(C)CC=O>>CC(C)C(C)(C)C/C=N/CC(=O)OC(C)(C)C,,ClCCl,,,,test
US20090131398A1,CCN(CC)[C@H]1C[C@H](O)C1>>CCN(CC)[C@H]1C[C@H](O)C1,,CO,,Cl,[Na+].[OH-],test
US20100317704A1,Cc1cn(-c2ccc(C3=NC4(CCCOC4)NC3=O)cc2)cn1.O=C(CBr)Nc1cccc(C(F)(F)F)c1>>Cc1cn(-c2ccc(C3=NC4(CCCOC4)N(CC(=O)Nc4cccc(C(F)(F)F)c4)C3=O)cc2)cn1,,CN(C)C=O,,O,[H-].[Na+],test
US20060074075A1,N#CCc1c[nH]c2cc([N+](=O)[O-])ccc12>>N#CCc1c[nH]c2cc(N)ccc12,[Pd],CCO,,,,test
US20100048568A1,BrBr.Nc1ccc(F)nc1>>Nc1ccc(F)nc1Br,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US05428038,COc1cc2ccc(=O)oc2cc1OCC1CO1.FC(F)(F)c1cccc(N2CCNCC2)c1>>COc1cc2ccc(=O)oc2cc1OCC(O)CN1CCN(c2cccc(C(F)(F)F)c2)CC1,,CC(C)O,,CO,Cl,test
US04645845,CC(=O)Oc1c(C)c(C)c2c(c1C)CC[C@@](C)(CCOC(=O)C(C)Oc1cccc3ccccc13)O2>>C[C@H](O)C1CCc2ccccc2O1,,CO,,[K+].[OH-],,test
US20150011782A1,C[Si](C)(C)N=[N+]=[N-].OCC1OC1Cc1ccccc1>>[N-]=[N+]=NC(Cc1ccccc1)C(O)CO,CC(C)O[Ti](OC(C)C)(OC(C)C)OC(C)C,c1ccccc1,,,,test
US20020028771A1,C(=NC1CCCCC1)=NC1CCCCC1.CCCCCCCCCCCCCCCCS(=O)(=O)N[C@@H](CC(=O)O)C(=O)OC(C)(C)C.CN(C)C=O.On1nnc2ccccc21>>C=Cc1ccccc1.C=Cc1ccccc1C=C,,CN(C)C=O,,,,test
US20100184768A1,CC(C)=CCC/C(C)=C/CC/C(C)=C/CSC[C@H](N)C(=O)O.CCOC(=O)CCN=C=S>>CCOC(=O)CCNC(=S)N[C@@H](CSC/C=C(\C)CC/C=C(\C)CCC=C(C)C)C(=O)O,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
USRE039112E1,CCC1(O)CCCCC1.COC(=O)CCCn1c(-c2cccc(F)c2)nc2c(N)nc(I)nc21>>COC(=O)CCCn1c(-c2cccc(F)c2)nc2c(N)nc(C#CC3(O)CCCCC3)nc21,[Cu]I,CCN(CC)CC,,CN(C)C=O,,test
US20060189631A1,COc1ccc(C(=O)C(Br)c2ccc(SC)cc2)cc1.Cc1cc(C)nc(N)n1>>COc1ccc(-c2nc3nc(C)cc(C)n3c2-c2ccc(SC)cc2)cc1,,CC#N,CCOC(C)=O,,,test
US20130289020A1,Nc1ccncc1N.O=C(O)c1cccc(Cl)n1>>Clc1cccc(-c2nc3cnccc3[nH]2)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04243666,COc1ccc(CN)c(OC)c1.O=C(Cl)C1CCN(C(=O)OCc2ccccc2)CC1>>COc1ccc(CNC(=O)C2CCNCC2)c(OC)c1,[Pd],CCO,,,,test
US20130072473A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1CCc2c(sc(N)c2-c2nc3ccccc3s2)C1>>CC(=O)Nc1sc2c(c1-c1nc3ccccc3s1)CCN(C(C)=O)C2,,ClCCl,,CC(=O)O,,test
US20070219251A1,CC(=O)OC(C)=O.CC(C)Oc1ccc(Oc2ncc(-c3ccc(C(C)N)cc3)s2)cc1>>CC(=O)NC(C)c1ccc(-c2cnc(Oc3ccc(OC(C)C)cc3)s2)cc1,,ClCCl,,CCN(CC)CC,,test
US05240938,COC(=O)C(Oc1ccc(C)cc1C(=O)c1ccccc1)c1ccccc1.O=C1CCC(=O)N1Br>>COC(=O)C(Oc1ccc(CBr)cc1C(=O)c1ccccc1)c1ccccc1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US03943140,CCOC(=O)/C=C(/C)N.CCOC(=O)CC(=O)C(=O)OCC.COc1ccc(C=O)cc1F>>CCOC(=O)C1=C(C(=O)OCC)C(c2ccc(OC)c(F)c2)C(C(=O)OCC)=C(C)N1,,CCO,,,,test
US20050124692A1,CC(C)(C)[Si](C)(C)OCC1Cc2ccc3c(c2O1)CCC3>>OCC1Cc2ccc3c(c2O1)CCC3,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140349989A1,O=C(OC(=O)C(F)(F)F)C(F)(F)F.O=[N+]([O-])c1ccc(-n2cc(C3=CCNCC3)c3ccccc32)cc1>>O=C(N1CC=C(c2cn(-c3ccc([N+](=O)[O-])cc3)c3ccccc23)CC1)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20160102088A1,COc1cccc(N)c1.O=C(c1cccnc1)N1CCc2nc(Cl)ncc2C1>>COc1cccc(Nc2ncc3c(n2)CCN(C(=O)c2cccnc2)C3)c1,,CC(C)O,,CCOC(C)=O,,test
US20150336979A1,[N-]=[N+]=N[C@H]1CO[C@@H]2[C@@H](C#Cc3ccc4c(c3)OCO4)CO[C@H]12>>N[C@H]1CO[C@@H]2[C@@H](C#Cc3ccc4c(c3)OCO4)CO[C@H]12,,CO,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20160002225A1,CC#CC(=O)O.Cc1cnc(NC(=O)c2ccc(Oc3ccnc4[nH]nc(N[C@@H]5CCCNC5)c34)cc2)s1>>CC#CC(=O)N1CCC[C@@H](Nc2n[nH]c3nccc(Oc4ccc(C(=O)Nc5ncc(C)s5)cc4)c23)C1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20110015204A1,C[C@@H]1C[C@@H](O)c2ncnc(N3CCN(C(=O)[C@@H](c4ccc(Br)c(F)c4)[C@@H]4CCC(C)(C)N4C(=O)OC(C)(C)C)CC3)c21.Cl.ClCCl>>C[C@@H]1C[C@@H](O)c2ncnc(N3CCN(C(=O)[C@@H](c4ccc(Br)c(F)c4)[C@@H]4CCC(C)(C)N4)CC3)c21.Cl.Cl,,ClCCl,,,,test
US20120214785A1,CC(=O)NC(C)Cc1ccc(C#Cc2cnc(Cl)nc2)cc1.CNCCOC>>COCCN(C)c1ncc(C#Cc2ccc(CC(C)NC(C)=O)cc2)cn1,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US05189054,CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1N.ClCCl.O=C(Cl)c1cccc(F)c1>>CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1NCC(=O)c1cccc(F)c1,,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US20060135578A1,CCOP(OCC)OCC.CCc1nc(CCl)co1>>CCOP(=O)(Cc1coc(CC)n1)OCC,,CCO,CCOC(C)=O,,,test
US20160145202A1,CNC(=O)OCc1cc(C(C)=O)ccc1Cl.NO>>CNC(=O)OCc1cc(/C(C)=N/O)ccc1Cl,,CCO,,CCN(C(C)C)C(C)C,,test
US20060074119A1,COC(=O)c1sc(-n2cnc3ccccc32)cc1CCc1ccccc1.N>>NC(=O)c1sc(-n2cnc3ccccc32)cc1CCc1ccccc1,,CO,,,,test
US20150266848A1,COC(C)(C)OC.OC(COCc1ccccc1)C(O)c1ccccc1Cl>>CC1(C)OC(COCc2ccccc2)C(c2ccccc2Cl)O1,,ClCCl,,Cc1ccc(S(=O)(=O)Cl)cc1,,test
US20100029619A1,CCOC(=O)CC(C)(C)c1ccc(C(=O)Nc2cn3cc(Cl)ccc3n2)cc1>>CC(C)(CC(=O)O)c1ccc(C(=O)Nc2cn3cc(Cl)ccc3n2)cc1,,C1CCOC1,,CO,[Li+].[OH-],test
US06054483,CCOC(C)OCCC#CCC#CC(C)OC(=O)c1ccccc1>>CC(O)C#CCC#CCCO,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20100179216A1,CCC(CO)(CO)NC(=O)OC(C)(C)C.COCCl.ClCCl.O>>CCCN(C(=O)OC(C)(C)C)C(CO)OCOC,,ClCCl,,CCN(C(C)C)C(C)C,,test
US07217714B1,CC(C)(C)OC(=O)N1CCC(C#N)CC1.NO>>CC(C)(C)OC(=O)N1CCC(C(N)=NO)CC1,,CO,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20110190330A1,COC(=O)c1cc(F)c(O)c(C2=CCCC2(C)C)c1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1cc(F)c(OS(=O)(=O)C(F)(F)F)c(C2=CCCC2(C)C)c1,CN(C)c1ccncc1,ClCCl,,,,test
US20100298298A1,COc1ccc(Cn2c(=O)c3cc(OCc4ccccc4)ccc3n(C3CCN(C=O)CC3)c2=O)cc1OC>>COc1ccc(Cn2c(=O)c3cc(O)ccc3n(C3CCN(C=O)CC3)c2=O)cc1OC,[Pd],CCO,,O=C[O-].[NH4+],,test
US20120157428A1,CS(=O)(=O)Cl.Cc1noc(CO)c1-c1ccccc1C(=O)c1ccc(Cl)cc1>>Cc1noc(COS(C)(=O)=O)c1-c1ccccc1C(=O)c1ccc(Cl)cc1,,O,,CCN(CC)CC,ClCCl,test
US03989841,CI.Cc1c(CC(=O)O)ccc2c1Cc1cc(O)ccc1-2>>COc1ccc2c(c1)Cc1c-2ccc(CC(=O)O)c1C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US07875605B2,CN1CCN(C(=O)c2c[nH]c3ccccc23)CC1>>CN1CCN(Cc2c[nH]c3ccccc23)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070027160A1,FC(F)(F)c1cnc2c(N3CCC4(CC3)OCCO4)cccc2c1>>O=C1CCN(c2cccc3cc(C(F)(F)F)cnc23)CC1,,C1CCOC1,,Cl,,test
US20060276475A1,CC#N.Cc1cc(COS(C)(=O)=O)no1.Nc1nc(NCC2CCCN2)nc2nc(-c3ccco3)nn12>>Cc1noc(C)c1CN1CCCC1CNc1nc(N)n2nc(-c3ccco3)nc2n1,,CC#N,,CCN(CC)CC,,test
US20030153752A1,Nc1ncnc2[nH]cc(-c3ccc(Oc4ccccc4)cc3)c12.O=C1c2ccccc2C(=O)N1CCCCCCCCBr>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)cn2CCCCCCCCN1C(=O)c2ccccc2C1=O,,CN(C)C=O,,[H-].[Na+],,test
US20060074075A1,CC(C)(C)c1ccc(O)c(C(C)(C)C)c1.CCOP(=O)(Cl)OCC>>CCOP(=O)(OCC)Oc1ccc(C(C)(C)C)cc1C(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20140148468A1,COC(=O)CCSc1ncsc1C(=O)OC>>COC(=O)c1scnc1S,,CO,,[Na+].[OH-],,test
US20090023707A1,COC(=O)c1ccc(Nc2ccccc2[N+](=O)[O-])cc1>>COC(=O)c1ccc(Nc2ccccc2N)cc1,[Pd],CO,,NN,O,test
US03966780,CCOP(=O)(OCC)/C(C)=C(/C)C(=O)OC.COC(C)(C)CCCC(C)CC=O>>COC(=O)C(C)=CC=CCC(C)CCCC(C)(C)OC,,CO,c1ccccc1,[Na],,test
US20010031874A1,CCS(=O)(=O)Cl.COc1ccc(C(=O)Nc2ccccc2)cc1N>>CCS(=O)(=O)Nc1cc(C(=O)Nc2ccccc2)ccc1OC,,c1ccncc1,,,,test
US20100298324A1,COC(=O)c1ccc(C(=O)OC)c(N=C=S)c1.Nc1ccncn1>>O=C(O)c1ccc2c(=O)n(-c3ccncn3)c(=S)[nH]c2c1,,CN(C)C=O,,Cl,[Na+].[OH-],test
US20130157977A1,CC(C)c1nc2c(Br)cc([N+](=O)[O-])cc2[nH]1.Cc1c(CBr)cccc1C(F)(F)F>>Cc1c(Cn2c(C(C)C)nc3c(Br)cc([N+](=O)[O-])cc32)cccc1C(F)(F)F,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130102776A1,COc1ccc2c(c1CN1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1c[nH]c3ncccc13)C2=O>>COc1ccc2c(c1CN1CCNCC1)O/C(=C\c1c[nH]c3ncccc13)C2=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150232435A1,CC(C)(C)c1nc(N2CCN(CCCCN)CC2)cc(C(F)(F)F)n1.O=C(n1ccnc1)n1ccnc1.c1ccc2c3c([nH]c2c1)CCNC3>>CC(C)(C)c1nc(N2CCN(CCCCNC(=O)N3CCc4[nH]c5ccccc5c4C3)CC2)cc(C(F)(F)F)n1,,CO,ClC(Cl)Cl,,,test
US05036064,Cc1cc(S)n2ncc(C(=O)O)c2n1>>Cc1cc(S)n2nccc2n1,,Cl,,,,test
US20050101595A1,CC1(C)CCCNC1.Nc1nc(NC2CCN(S(=O)(=O)CCCI)CC2)sc1C(=O)c1c(F)cccc1F>>CC1(C)CCCN(CCCS(=O)(=O)N2CCC(Nc3nc(N)c(C(=O)c4c(F)cccc4F)s3)CC2)C1,,CS(C)=O,,,,test
US20110034455A1,CCOC(=O)C(C)C1CC2(CCNCC2)c2c(Br)cccc21.NC1C2CC3CC(C2)CC1C3.O=C(n1ccnc1)n1ccnc1>>CCOC(=O)C(C)C1CC2(CCN(C(=O)NC3C4CC5CC(C4)CC3C5)CC2)c2c(Br)cccc21,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20070287697A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)CNC1=S.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)CN(CC(F)(F)F)C1=S,,CN(C)C=O,,O,[H-].[Na+],test
US20050093031A1,Brc1ccc(Br)s1.CCCCCCc1ccc(-c2ccc([Sn](CCCC)(CCCC)CCCC)s2)cc1>>CCCCCCc1ccc(-c2ccc([Sn](CCCC)(CCCC)CCCC)s2)s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20100216836A1,CCOC(=O)CC1CCCN(CC2COc3ccccc3O2)C1>>OCCC1CCCN(CC2COc3ccccc3O2)C1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20160168139A1,CCCC[Sn](CCCC)(CCCC)[Sn](CCCC)(CCCC)CCCC.COc1ccc(COc2cc(N3CCOCC3)cc(Cl)n2)cc1>>CCCC[Sn](CCCC)(CCCC)c1cc(N2CCOCC2)cc(OCc2ccc(OC)cc2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,[Cl-].[Li+],,test
US04530715,CC(=O)C1(n2cncn2)CC1.O=CC(Cl)(Cl)Cl>>O=C(C1CC1)C(C(O)C(Cl)(Cl)Cl)n1cncn1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20140005222A1,CCOC(=O)c1cc(C)c(NC(=O)c2nc(N3CCC(C)(O)CC3)ccc2C)c(C)c1>>Cc1ccc(N2CCC(C)(O)CC2)nc1C(=O)Nc1c(C)cc(C(=O)O)cc1C,,C1CCOC1,,CO,[Na+].[OH-],test
US20060258721A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCNC1CC=C(c2c[nH]c3ccc([N+](=O)[O-])cc23)CC1>>CCN(C(=O)OC(C)(C)C)C1CC=C(c2c[nH]c3ccc([N+](=O)[O-])cc23)CC1,,C1COCCO1,,CCN(CC)CC,,test
US20050209283A1,COC(=O)c1ccc2c(c1C)OC(CO)CO2.CO[C@](C(=O)Cl)(c1ccccc1)C(F)(F)F>>COC(=O)c1ccc2c(c1C)OC(COC(=O)C(OC)(c1ccccc1)C(F)(F)F)CO2,,ClCCl,,CCN(CC)CC,,test
US20130029980A1,CCOC(=O)C(C)Cc1ccc(Cl)cc1>>CC(CO)Cc1ccc(Cl)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100216836A1,CC1(COS(C)(=O)=O)CCCN(CC2COc3ccccc3O2)C1.OCC(F)(F)F>>CC1(COCC(F)(F)F)CCCN(CC2COc3ccccc3O2)C1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20090068140A1,CC(C)[C@H](Nc1nccs1)C(=O)N1CCC[C@H]1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1.CC(C)[C@H](Nc1nccs1)C(=O)N1CCC[C@H]1c1ncc(-c2ccc(Br)cc2)[nH]1>>CC(C)[C@H](Nc1nccs1)C(=O)N1CCC[C@H]1c1nc(-c2ccc(-c3ccc(-c4c[nH]c([C@@H]5CCCN5C(=O)[C@@H](Nc5nccs5)C(C)C)n4)cc3)cc2)c[nH]1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])O.[Na+],,test
US04804773,CC[Si](CC)(CC)OC1(C(F)(F)F)C=CC(=O)C=C1>>O=C1C=CC(O)(C(F)(F)F)C=C1,,O,,CCO,Cl,test
US20080085890A1,CON=Cc1ccn(-c2ccoc2)c(=O)c1>>NCc1ccn(-c2ccoc2)c(=O)c1,[Zn],CC(=O)O,,,,test
US20150148332A1,Cc1ncc(C)n2nc(C=Cc3nc(N(C)C4CC4)nn3C)nc12>>Cc1ncc(C)n2nc(CCc3nc(N(C)C4CC4)nn3C)nc12,[Pd],CO,,,,test
US20040116633A1,CC(C)(Br)C(=O)NC(C)(C)C(=O)O>>CC(C)(Br)C1=NC(C)(C)C(=O)O1,,CC(C)=O,,CCN(CC)CC,CCOC(=O)Cl,test
US20150344423A1,CCOC(=O)c1nc(-c2ccc(S(=O)(=O)NC(C)(C)C)c3ccccc23)n(CC2CCCCC2)c1C>>Cc1c(C(=O)O)nc(-c2ccc(S(=O)(=O)NC(C)(C)C)c3ccccc23)n1CC1CCCCC1,,CCO,O,Cl,[K+].[OH-],test
US04234595,COc1ccc2[nH]cc(CC(C)(C)[N+](=O)[O-])c2c1>>COc1ccc2[nH]cc(CC(C)(C)N)c2c1,[Ni],,,NN,O,test
US06281219B1,CNc1cccc(C(F)(F)F)c1.Clc1cc(Cl)ncn1>>CN(c1cccc(C(F)(F)F)c1)c1cc(Cl)ncn1,,CCOC(C)=O,,,,test
US20090182023A1,CC(=O)NCCC1CCc2ccc(N)c(O)c21.CCC(=O)OC(=O)CC>>CCC(=O)Nc1ccc2c(c1O)C(CCNC(C)=O)CC2,,c1ccncc1,,Cl,O,test
US20110092517A1,CCOC(=O)CBr.Cc1cc(C(=O)CCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C(C)C)ccc1O>>CCOC(=O)COc1ccc(C(=O)CCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C(C)C)cc1C,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100105661A1,COCCNC(=O)c1nc(-c2cnc3[nH]ccc3c2Cl)no1.C[C@@H]1CCCC[C@@H]1N>>COCCNC(=O)C(=O)Nc1nn([C@H]2CCCC[C@H]2C)c2c1cnc1[nH]ccc12,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,Cl,test
US08471004B2,C=CC[C@@H]1CCC(CN(C(=O)OCc2ccccc2)[C@@H](C)C(=O)OC)N1C(=O)OC(C)(C)C>>C=CCC1CC[C@H]2CN(C(=O)OCc3ccccc3)[C@@H](C)C(=O)N12,,Cl,,O=C([O-])[O-].[K+].[K+],,test
US20110122475A1,COC(=O)C1=C(O)c2ccccc2C2OCC(c3ccccc3)(c3ccc(N4CCCC4)cc3)C=C12.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)C1=C(OS(=O)(=O)C(F)(F)F)c2ccccc2C2OCC(c3ccccc3)(c3ccc(N4CCCC4)cc3)C=C12,,ClCCl,,c1ccncc1,,test
US04826986,CCCBr.CCOC(=O)[C@@H]1CC2(CC[C@H]1N)OCCO2>>CCCN[C@@H]1CCC2(C[C@H]1C(=O)OCC)OCCO2,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060009493A1,COc1ccc(C(C)(O)C(=O)[O-])c(C)c1.NN>>COc1ccc(C(O)C(=O)NN)cc1,,CO,,O,,test
US05025008,Brc1cc(Br)c2c(c1)oc1ccccc12.CSSC>>CSc1cc(Br)cc2oc3ccccc3c12,,C1CCOC1,CCOC(C)=O,CCCCCC,[Li]CCCC,test
US20130040933A1,CC(C)(C)OC(=O)N1CCN[C@@H](C(=O)NCC(F)(F)F)C1.Clc1cncc(Cl)n1>>CC(C)(C)OC(=O)N1CCN(c2cncc(Cl)n2)[C@@H](C(=O)NCC(F)(F)F)C1,,CN(C)C=O,,CCN(CC)CC,,test
US20060111375A1,COc1cc(O)c(C(C)=O)c(OC)c1.COc1cc2nccc(Cl)c2cc1OC>>COc1cc(OC)c(C(C)=O)c(Oc2ccnc3cc(OC)c(OC)cc23)c1,CN(C)c1ccncc1,Clc1ccccc1Cl,,,,test
US20090018054A1,ICI.N#Cc1cc(C(F)(F)F)ccc1N>>N#Cc1cc(C(F)(F)F)ccc1I,,CC#N,CCOCC,CC(C)(C)ON=O,,test
US20050010052A1,CC(C)(C)OC(=O)NCCS.O=C(O)c1cc(Cl)ncc1Cl>>CC(C)(C)OC(=O)NCCSc1cc(C(=O)O)c(Cl)cn1,,CN(C)C=O,,[H-].[Na+],,test
US20050239857A1,CC(C)c1c(C(=O)Oc2c(F)c(F)c(F)c(F)c2F)nc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@H](CC(=O)OC(C)(C)C)OC(C)(C)O1.NCc1ccccc1>>CC(C)c1c(C(=O)NCc2ccccc2)nc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20120316124A1,CC(=O)c1ccc(F)c(C#N)c1.O=C(c1cc(Cl)cc(Cl)c1)C(F)(F)F>>N#Cc1cc(C(=O)C=C(c2cc(Cl)cc(Cl)c2)C(F)(F)F)ccc1F,,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20130102778A1,CC(C)N.Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)O)cn1>>Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)NC(C)C)cn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US04618683,COc1ccc2c(c1OC)CC[C@@H]1CNC(=O)[C@@H]21.Cl>>COc1ccc2c(c1OC)CC[C@@H]1CNC[C@@H]21.Cl,,C1CCOC1,,B,,test
US05104867,CI.COc1ccc(CS[C@@H]2CN[C@H](C(=O)N(C)C)C2)cc1>>COc1ccc(CS[C@H]2C[C@@H](C(=O)N(C)C)N(C)C2)cc1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20080064696A1,CC1(C)OB(c2ccc(N)c(F)c2)OC1(C)C.O=S(=O)(Cl)c1cccc(Cl)c1Cl>>CC1(C)OB(c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)c(F)c2)OC1(C)C,,ClCCl,,c1ccncc1,,test
US20070004786A1,C#Cc1ccc(F)c(Br)c1.CCn1cc(I)cc1S(C)(=O)=O>>CCn1cc(C#Cc2ccc(F)c(Br)c2)cc1S(C)(=O)=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090163489A1,Cc1ccc(S(=O)(=O)N=c2ccc(Br)c[nH]2)cc1.NC(=O)CI>>Cc1ccc(S(=O)(=O)NC2C=CC(Br)=CN2CC(N)=O)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20090105244A1,CSCCO.Cc1c(Cl)c(S(C)=O)nc2sc(C(=O)NC3CC3)c(N)c12>>CSCCOc1nc2sc(C(=O)NC3CC3)c(N)c2c(C)c1Cl,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US03989701,Cl.Nc1cc(C(=O)c2ccccc2)ccc1N1CCOCC1>>Cl.Nc1cc(C(=O)c2ccccc2)ccc1N1CCOCC1,,CC(C)O,,,,test
US20070191447A1,CN(C(=O)Cn1c(=O)oc2ccc(Br)cc21)c1ccccc1.O=S([O-])c1ccccc1>>CN(C(=O)Cn1c(=O)oc2ccc(S(=O)(=O)c3ccccc3)cc21)c1ccccc1,I[Cu]I,CN(C)C=O,,O,,test
US20140296243A1,COC(=O)c1cc(N(C)[C@@H](C)c2ccccc2)nn2c(C)nnc12>>Cc1nnc2c(C(=O)O)cc(N(C)[C@@H](C)c3ccccc3)nn12,,CO,,[Li+].[OH-],,test
US20060167266A1,CSc1nsc(Cl)n1.OB(O)c1ccccc1Cl>>CSc1nsc(-c2cccc(Cl)c2)n1,,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
USRE029358,CCl.Cl.NNC1=NCCCN1.S=C1NCCCN1>>CSC1=NCCCN1.Cl.NN,,CC(C)O,,,,test
US20070281952A1,OB(O)c1ccc(F)cc1.Oc1ccc2cc(Br)ccc2c1>>Oc1ccc2cc(-c3ccc(F)cc3)ccc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US04840971,CCOc1ccc(C(C=O)C(F)(F)F)cc1>>CCOc1ccc(C(CO)C(F)(F)F)cc1,,CCO,,[BH4-].[Na+],,test
US20140235628A1,Cc1c(OCC2CCN(C(=O)OC(C)(C)C)CC2)ccc2c1COC2=O>>Cc1c(OCC2CCNCC2)ccc2c1COC2=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030139285A1,CCOP(Cl)OCC.COc1c(C(C)(C)C)cc(P(c2cc(C(C)(C)C)c(OC)c(C(C)(C)C)c2)c2ccccc2Br)cc1C(C)(C)C>>CCOP(OCC)c1ccccc1P(c1cc(C(C)(C)C)c(OC)c(C(C)(C)C)c1)c1cc(C(C)(C)C)c(OC)c(C(C)(C)C)c1,,C1CCOC1,,,,test
US20100267725A1,NCc1cccnc1.O=C(NCc1ccc(Oc2ccccc2)cc1)c1nnc(-c2cc(Cl)c(O)c(Cl)c2)o1>>O=C(NCc1ccc(Oc2ccccc2)cc1)c1nnc(-c2cc(Cl)c(O)c(Cl)c2)n1Cc1cccnc1,,Cc1ccccc1C,,,,test
US20080090856A1,CC(C)(C)[Si](C)(C)Cl.Nc1ccc(Oc2ccnc(NCCO)c2)cc1F>>CC(C)(C)[Si](C)(C)OCCNc1cc(Oc2ccc(N)c(F)c2)ccn1,,CN(C)C=O,,c1c[nH]cn1,,test
US05304557,Nc1cc(C(F)(F)F)ccc1Br.O=C(Cl)CCl>>O=C(CCl)Nc1cc(C(F)(F)F)ccc1Br,,ClCCl,,CCN(CC)CC,,test
US04623658,CCCOC(=O)N(C)SNc1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1F.O=C=NC(=O)c1c(F)cccc1F>>CCCOC(=O)N(C)SN(C(=O)NC(=O)c1c(F)cccc1F)c1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1F,,ClCCl,,,,test
US20150119404A1,COC(=O)C(=CC(C)(C)NC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C>>CC1(C)CC(NC(=O)OC(C)(C)C)C(=O)N1,[Pd],CO,,,,test
US20030092712A1,Cc1c(Br)cc(Br)nc1-c1ccc(F)cc1Cl.O=C1CCC(=O)N1Br>>Fc1ccc(-c2nc(Br)cc(Br)c2CBr)c(Cl)c1,,ClCCCl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20080249092A1,Cl.O=S(=O)(c1ccccc1)c1cnc2c(NCCC3CCOCC3)cccc2c1>>Cl.O=S(=O)(c1ccccc1)c1cnc2c(NCCC3CCOCC3)cccc2c1,,CCOCC,,CO,,test
US05240937,Cl.O=[N+]([O-])c1cnccc1NCc1ccccc1F>>Nc1c(NCc2ccccc2F)ccnc1Cl,,CCOC(C)=O,,CO,,test
US20160031879A1,COCCc1cc(C(=O)NCC2CCC(F)(F)CC2)c2c(Cl)cccn12>>O=C(NCC1CCC(F)(F)CC1)c1cc(CCO)n2cccc(Cl)c12,,CCOC(C)=O,,Cl,c1ccncc1,test
US20060040923A1,COc1cc([N+](=O)[O-])ccc1C(=O)O.O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1ccc(Cl)c(Cl)c1>>COc1cc([N+](=O)[O-])ccc1C(=O)NC1N=C(c2ccccc2)c2ccccc2NC1=O,,C1CCOC1,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090197871A1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1cccc(B(O)O)c1>>CC(C)(C)OC(=O)N1CCN(Cc2cccc(B(O)O)c2)CC1,,CCOC(C)=O,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20110251314A1,CCCCCCCCCCCCCCCCP(O)O.OO>>CCCCCCCCCCCCCCCCP(=O)(O)O,,O,,,,test
US20120115850A1,CS(=O)(=O)c1ccc(F)cc1F.Nc1cccc2ccccc12>>CS(=O)(=O)c1ccc(F)cc1Nc1cccc2ccccc12,,CN(C)C=O,O,[H-].[Na+],,test
US04960940,O=[N+]([O-])c1cc(CS(=O)(=O)CCO)ccc1CS(=O)(=O)CCO>>Nc1cc(CS(=O)(=O)CCO)ccc1CS(=O)(=O)CCO,[Pd],,,,,test
US07091346B1,CI.COc1cc(Nc2nc(Cl)nc3nc[nH]c23)cc(OC)c1OC>>COc1cc(Nc2nc(Cl)nc3c2ncn3C)cc(OC)c1OC,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20020132827A1,COc1ccc(-c2cncc3cccc([N+](=O)[O-])c23)c(O)c1OC>>COc1ccc2c(c1OC)Oc1cccc3cncc-2c13,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110244481A1,CC(C)(C)[Si](C)(C)Oc1ccc(-c2cnc(N)c(Br)n2)cc1.OB(O)c1cc2sccc2s1>>CC(C)(C)[Si](C)(C)Oc1ccc(-c2cnc(N)c(-c3cc4sccc4s3)n2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],test
US20160052884A1,COCCC(C(=O)O)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O.Nc1ccc2c(c1)=NC(=O)N=2>>COCCC(C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O,,CN(C)C=O,,CC(C)N=C=NC(C)C,,test
US20020055631A1,CCOC(=O)c1ccc(N2CCC(=CCC3OCCCO3)CC2)cc1>>CCOC(=O)c1ccc(N2CCC(CCC3OCCCO3)CC2)cc1,[Pd],CCOC(C)=O,,,,test
US20030149004A1,CCCN1CCNCC1.O=C1CCCC(=O)O1>>CCCN1CCN(C(=O)CCCC(=O)O)CC1,,C1COCCO1,,,,test
US20100280071A1,CCO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C)ccc3N)CC2)CC1.ClCCl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCO[C@@H]1CC[C@@H](N2CCC(n3c(=O)[nH]c4ccc(C)cc43)CC2)CC1.Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120295884A1,CO[C@@H]1CCN(C(=O)OC(C)(C)C)[C@@H]1C(=O)O.NCc1cccc(Cl)c1F>>CO[C@@H]1CCN(C(=O)OC(C)(C)C)[C@@H]1C(=O)NCc1cccc(Cl)c1F,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050004133A1,CC(C)(C)c1ccc(C(=O)Cl)cc1.Nc1ccc2[nH]c(=O)sc2c1>>CC(C)(C)c1ccc(C(=O)Nc2ccc3[nH]c(=O)sc3c2)cc1,,CCN(CC)CC,CN(C)C=O,,,test
US20150105365A1,CCN(CC)c1nc2ccc(Br)cc2c(Cl)c1Oc1ccccc1.Cn1cncc1C(=O)c1ccccn1>>CCN(CC)c1nc2ccc(C(O)(c3ccccn3)c3cncn3C)cc2c(Cl)c1Oc1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US20120114739A1,COC(=O)Cc1ccc(O)cc1.C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)c1cc(Cl)nc2ccnn12>>COC(=O)Cc1ccc(Oc2cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n3nccc3n2)cc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20130237501A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(c3ccc([N+](=O)[O-])c(C#N)c3)S(C)(=O)=O)c(C3CC3)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(c3ccc(N)c(C#N)c3)S(C)(=O)=O)c(C3CC3)cc12,,C1CCOC1,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20160176848A1,COC(=O)c1ccn2cccnc12.O=Cc1cc2c(cc1Br)OCO2>>COC(=O)c1cc(-c2cc3c(cc2C=O)OCO3)n2cccnc12,,CC(=O)N(C)C,,CC(=O)[O-].[K+],,test
US04128548,COC(=O)C(C)(C)C(N)Cc1ccc(OC)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)C(C)(C)C(Cc1ccc(OC)cc1)NS(=O)(=O)c1ccc(C)cc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20130059838A1,Brc1ccc2c(c1)CCNCC2.COC(=O)Cl>>COC(=O)N1CCc2ccc(Br)cc2CC1,,ClCCl,,CCN(CC)CC,O,test
US20010023248A1,COC(=O)c1cc(N)ccc1OC.O=C(Cl)c1ccccc1>>COC(=O)c1cc(NC(=O)c2ccccc2)ccc1OC,,ClCCl,,CCN(CC)CC,,test
US05731448,CS(=O)(=O)Cl.O=C(O)CCCCC(O)CCCl>>CS(=O)(=O)OC(CCCl)CCCCC(=O)O,,Cc1ccccc1,,CCN(CC)CC,O,test
US20150031540A1,C=C(C)B1OC(C)(C)C(C)(C)O1.COc1c(Br)nn(C)c(=O)c1-n1c(Cl)c(Cl)c2ccccc21>>C=C(C)c1nn(C)c(=O)c(-n2c(Cl)c(Cl)c3ccccc32)c1OC,,CCOC(C)=O,COCCOC,[Cs+].[F-],,test
US05158966,CC(C)(C)c1cc(C=C2SC(=S)NC2=O)cc(C(C)(C)C)c1O>>CC(C)(C)c1cc(C=C2SCNC2=O)cc(C(C)(C)C)c1O,[Pd],CCO,,,,test
US03939268,CCS.Clc1nc(Cl)c2ncccc2n1>>CCSc1nc(Cl)nc2cccnc12,,CC(C)=O,O,[Na+].[OH-],,test
US20060189606A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc2c(C#N)c[nH]c2c1>>COc1ccc2c(C#N)cn(C(=O)OC(C)(C)C)c2c1,CN(C)c1ccncc1,ClCCl,,O,,test
US06506747B1,N#CCCCBr.Oc1ccc2c(I)cccc2c1>>N#CCCCOc1cccc2c(I)cccc12,,CCO,O,C,C[O-].[Na+],test
US20080262056A1,CCC(=O)OC(=O)CC.CN1C(=O)Cc2cc(N3C[C@@H](CN)OC3=O)cc(F)c21>>CCC(=O)NC[C@H]1CN(c2cc(F)c3c(c2)CC(=O)N3C)C(=O)O1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04476131,CC(CCCc1ccccc1)OS(C)(=O)=O.O=C1CC2CCC(=O)N2c2cc(O)cc(O)c21>>CC(CCCc1ccccc1)Oc1cc(O)c2c(c1)N1C(=O)CCC1CC2=O,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20050009828A1,CCOC(=O)c1cc2cc(OCCOC)ncc2n1Cc1cc(-c2ccc(Cl)s2)on1>>COCCOc1cc2cc(C(=O)O)n(Cc3cc(-c4ccc(Cl)s4)on3)c2cn1,,C1CCOC1,CO,,,test
US20140228394A1,CCC(=O)CNc1ccc2ncsc2c1.Cc1ccncc1NC(=O)Oc1ccccc1>>CCC(=O)CN(C(=O)Nc1cnccc1C)c1ccc2ncsc2c1,,Cc1ccccc1,ClC(Cl)Cl,CO,,test
US05874382,CCN1c2cc(F)c([N+](=O)[O-])cc2CS1(=O)=O>>CCN1c2cc(F)c(N)cc2CS1(=O)=O,[Pd],C1CCOC1,,[H][H],,test
US20150166574A1,CCOC(=O)c1cn2nc(-c3ccccc3)sc2n1>>OCc1cn2nc(-c3ccccc3)sc2n1,,ClCCl,O,CC(C)C[AlH]CC(C)C,,test
US20090215788A1,CC(C)(C)C(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Br)nc12.Nc1ccccc1>>CC(C)(C)C(=O)c1cn(COCC[Si](C)(C)C)c2ncc(Nc3ccccc3)nc12,[Cu]I,CS(C)=O,,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US20070275987A1,CCCCc1cnc(Cl)c(C(=O)OC)c1>>CCCCc1cnc(Cl)c(C(=O)O)c1,,C1CCOC1,,[Li+].[OH-],,test
US05370819,C#CC1CCC(O[Si](C)(C)C)CC1.CCCCCC1CCC(CC=O)CC1>>CCCCCC1CCC(CC(O)C#CC2CCC(O[Si](C)(C)C)CC2)CC1,,C1CCOC1,,Cl,,test
US20080221131A1,Brc1nccs1.Cc1n[nH]c(C)c1Cc1sc2c(c1C(=O)N1C[C@H](O)CO1)c(=O)n(C)c(=O)n2C(C)C>>Cc1nn(-c2nccs2)c(C)c1Cc1sc2c(c1C(=O)N1C[C@H](O)CO1)c(=O)n(C)c(=O)n2C(C)C,[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=C([O-])[O-].[K+].[K+],test
US20080287437A1,CC(C)Oc1cc(Nc2nc(N[C@@H](C)c3ccc(F)cn3)ncc2Cl)n[nH]1.Cc1cc(Nc2nc(Cl)ncc2Cl)n[nH]1>>Cc1cc(Nc2nc(N[C@@H](C)c3ccc(F)cn3)ncc2Cl)n[nH]1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20120190681A1,COc1cc(N2CCNCC2)ccc1Nc1cc(Cc2c(F)cccc2Cl)cnc1C(N)=O.ClCCN1CCOCC1>>COc1cc(N2CCN(CCN3CCOCC3)CC2)ccc1Nc1cc(Cc2c(F)cccc2Cl)cnc1C(N)=O,,C1CCOC1,,CCN(CC)CC,Cl,test
US20100099681A1,COC(=O)c1ccccc1Nc1c(-c2cc3nccnc3c(F)c2F)c(C)nn1-c1ccccc1>>Cc1nn(-c2ccccc2)c(Nc2ccccc2C(=O)O)c1-c1cc2nccnc2c(F)c1F,,C1COCCO1,O,Cl,[Na+].[OH-],test
US07569686B1,COc1ccc(C(Cl)(c2ccccc2)c2ccc(OC)cc2)cc1.O=C(Nc1ccn(C2OC3(CO)CN(C(=O)COc4ccccc4)OC2C3O)c(=O)n1)c1ccccc1>>COc1ccc(C(OC(c2ccccc2)C23CN(C(=O)COc4ccccc4)OC(C(n4ccc(NC(=O)c5ccccc5)nc4=O)O2)C3O)c2ccc(OC)cc2)cc1,,c1ccncc1,,,,test
US20140163015A1,N[C@@]1(c2cc(Br)ccc2F)CO[C@@H](COCc2ccccc2)C[C@H]1CO.O=C(N=C=S)c1ccccc1>>O=C(NC(=S)N[C@@]1(c2cc(Br)ccc2F)CO[C@@H](COCc2ccccc2)C[C@H]1CO)c1ccccc1,,ClCCl,,,,test
US20040254188A1,CC(C)(C)c1ccc2c(c1)CCC2=O.CON>>CON=C1CCc2cc(C(C)(C)C)ccc21,,c1ccncc1,,Cl,,test
US20100331297A1,CC(C)(C)n1ncc2c(N)ncnc21.O=C(Cl)c1ccccc1>>CC(C)(C)n1ncc2c(NC(=O)c3ccccc3)ncnc21,,c1ccncc1,,O,,test
US20070249579A1,BrBr.c1ccc(-n2ccnn2)nc1>>Brc1cnnn1-c1ccccn1,,C1CCOC1,,[Li]CCCC,,test
US05093364,C[Si](C)(C)CCO.O=c1[nH]c2cc(F)ccc2c(=O)o1>>C[Si](C)(C)CCOC(=O)c1ccc(F)cc1N,,CC(C)OC(C)C,,[Na+].[OH-],,test
US20080161294A1,NCCO.O=Cc1ccccc1NC(=O)c1ccc(N2CCCC2)cc1Cl>>O=C(Nc1ccccc1C=NCCO)c1ccc(N2CCCC2)cc1Cl,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20140364426A1,CNN.COC(OC)C(C(OC)OC)[C@H]1C[C@H]2[C@@H](C)SC(NC(=O)c3ccccc3)=N[C@@]2(c2ccc(F)cc2F)CO1>>C[C@H]1SC(N)=N[C@@]2(c3ccc(F)cc3F)CO[C@@H](c3cnn(C)c3)C[C@@H]12,,CCO,O,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US20120232051A1,CNc1cnccc1Br.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnccc1Br,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20050203160A1,CC(C)(C)OC(=O)Cn1ccc2ccc(O[Si](C)(C)C(C)(C)C)cc21>>CC(C)(C)OC(=O)Cn1ccc2ccc(O)cc21,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04562210,C=CCN=C=O.NS(=O)(=O)c1ccccc1OC(Cl)=CCl>>C=CCNC(=O)NS(=O)(=O)c1ccccc1OC(Cl)=CCl,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2cc(-c3cc([C@@H](C)N4CCNCC4)cnc3F)nc(C)n2)cc1.CS(=O)(=O)Cl>>COc1ccc(CN(Cc2ccc(OC)cc2)c2cc(-c3cc([C@@H](C)N4CCN(S(C)(=O)=O)CC4)cnc3F)nc(C)n2)cc1,,ClCCl,,CCN(CC)CC,[Na+].[OH-],test
US20080287475A1,CC[C@@H](C)S(=O)N[C@@H](C)c1ncc(F)cn1.Cl>>C[C@H](N)c1ncc(F)cn1.Cl,,C1COCCO1,,,,test
US20120252778A1,CC(C)(C)OC(=O)N1CCC(CO)CC1.CCc1nn2c(C)cc(C)nc2c1Cc1ccc(O)cc1.ClCCl>>CCc1nn2c(C)cc(C)nc2c1Cc1ccc(OCC2CCNCC2)cc1.Cl,,CCOC(C)=O,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080312435A1,Cc1nc(N)sc1C(C)(C)C.O=S(=O)(Cl)c1cccc2ccccc12>>Cc1nc(NS(=O)(=O)c2cccc3ccccc23)sc1C(C)(C)C,,c1ccncc1,,O,,test
US20140323501A1,CCC(=O)O.CCOC(=O)C(CCc1ccc(Oc2ccc(C(=O)CCl)cc2)cc1)(NC(C)=O)C(=O)OCC>>CCOC(=O)C(CCc1ccc(Oc2ccc(C(=O)COC(=O)CC)cc2)cc1)(NC(C)=O)C(=O)OCC,,CC#N,,CCN(CC)CC,,test
US04699990,C=CCCOCCCCCCCCCCCCCCCC.O=C(OO)c1cccc(Cl)c1>>CCCCCCCCCCCCCCCCOCCC1CO1,,ClCCl,,,,test
US20090137609A1,CCC(CC)(c1ccc(CCC(OCOC)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(-c2cncc(CC(=O)OC)c2)c(C)c1>>CCC(CC)(c1ccc(CCC(O)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(-c2cncc(CC(=O)OC)c2)c(C)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04511573,CC(=O)O.N#Cc1ccc(Cc2c(-c3cccnc3)[nH]c3ccccc23)cc1.O=C([O-])O>>O=C(O)c1ccc(Cc2c(-c3cccnc3)[nH]c3ccccc23)cc1,,CC(=O)O,,Cl,,test
US09073882B2,CC(=O)O.Cc1c(CCN2CCNCC2)ccc2c1COC2=O.O=CCc1ccc2c(c1)COC2=O>>Cc1c(CCN2CCN(CCc3ccc4c(c3C)COC4=O)CC2)ccc2c1COC2=O,,ClCCl,,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20120149691A1,CC(C)CN1CCOC(CN)C1.N#Cc1cnn2cccc2c1Cl>>CC(C)CN1CCOC(CNc2c(C#N)cnn3cccc23)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US06001849,CC(C)(C)OC(=O)N1CCC[C@H]1c1cc2nc(Cl)ccc2o1.ClCCl>>Cl.Clc1ccc2oc([C@@H]3CCCN3)cc2n1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20070155730A1,NC(CCCCCC(=O)O)C(=O)O.O=c1[nH]c2ccc(Oc3ccccc3)cc2c(=O)o1>>O=C(O)CCCCCC1NC(=O)c2cc(Oc3ccccc3)ccc2NC1=O,,CC(=O)O,O,CCN(CC)CC,,test
US20090118305A1,CC(C)(C)OC(=O)N1CCC(n2cc(-c3cnc(N)c(-c4nc5ccccc5o4)c3)c(C=O)n2)CC1.C[Mg]Br>>CC(O)c1nn(C2CCN(C(=O)OC(C)(C)C)CC2)cc1-c1cnc(N)c(-c2nc3ccccc3o2)c1,,C1CCOC1,,,,test
US06326359B1,BrCc1ccccc1.COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CO)nc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C>>COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(COCc4ccccc4)nc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20090247567A1,C[Si](C)(C)N=[N+]=[N-].Nc1nc2c(s1)CCOc1cc(Br)ccc1-2>>[N-]=[N+]=Nc1nc2c(s1)CCOc1cc(Br)ccc1-2,,CC#N,,CC(C)(C)ON=O,,test
US05491153,CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1NCC(=O)c1ccccc1>>O=C(CNc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)c1ccccc1,,CCOC(C)=O,O,C1CCOC1,[Li+].[OH-],test
US20130210787A1,C=C(C)[C@@H]1CC[C@]2(N)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(OS(=O)(=O)C(F)(F)F)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CC(C)OC(=O)C1(C(=O)OC(C)C)CC2(C=C(B3OC(C)(C)C(C)(C)O3)C2)C1>>C=C(C)[C@@H]1CC[C@]2(N)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC7(C6)CC(C(=O)OC(C)C)(C(=O)OC(C)C)C7)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150258221A1,CCCCCCCCCCN(CCCCCCCCCC)C(=O)CN1CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1>>CCCCCCCCCCN(CCCCCCCCCC)C(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070142246A1,c1ccc(Nc2ccc3ncccc3c2)cc1>>c1ccc(Nc2ccc3c(c2)CCCN3)cc1,O=[Pt]=O,CC(=O)O,,,,test
US20120059002A1,COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(OCCN)c(C)c3)nc2c1.N#CBr>>COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(OCCNC#N)c(C)c3)nc2c1,,CO,,O=C([O-])O.[Na+],,test
US20150051197A1,C1CCOC1.C=CC(=O)OC.COC(=O)Cc1ccc(OC)cc1.O>>COC(=O)C1=C(O)CCC(C(=O)OC)(c2ccc(OC)cc2)C1,,O,,CC(C)(C)[O-].[K+],,test
US05571506,COC(=O)C=Cc1cc(OC(C)=O)c(OC)cc1C=O>>COC(=O)CCc1cc(OC(C)=O)c(OC)cc1C=O,[Pd],CCOC(C)=O,,,,test
US03958006,CC(=O)OO.CNC(=O)Oc1ccc(SC)c2c1CCCC2>>CNC(=O)Oc1ccc(S(C)=O)c2c1CCCC2,,CCCCCCC,CCOC(C)=O,,,test
US20120077814A1,O=C(O)c1ccc([N+](=O)[O-])cc1.O[C@@H]1C[C@H](c2csc3c(N[C@H]4CCc5ccccc54)ncnc23)C[C@H]1COCc1ccccc1>>O=C(O[C@H]1C[C@H](c2csc3c(N[C@H]4CCc5ccccc54)ncnc23)C[C@H]1COCc1ccccc1)c1ccc([N+](=O)[O-])cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05508408,CCC(CC)(CC(=O)Nc1cccc(OCc2ccc3ccc(OCc4ccccc4)cc3n2)c1)C(=O)O>>CCC(CC)(CC(=O)Nc1cccc(OCc2ccc3ccc(O)cc3n2)c1)C(=O)O,[Pd],C1CCOC1,,CCN(CC)CC,,test
US20050239777A1,C1CCNC1.COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCCC(=O)O>>COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCCC(=O)N1CCCC1,CN(C)C=O,CC(=O)N(C)C,ClCCl,O=C(Cl)C(=O)Cl,,test
US20040029902A1,CCOC(=O)c1nc(Nc2ccc3c(c2)OCCO3)nc(Nc2ccc3c(c2)OCCO3)c1[N+](=O)[O-].CCOC(=O)c1nc(Nc2cccc(O)c2)nc(Nc2cccc(O)c2)c1N>>CCOC(=O)c1nc(Nc2ccc3c(c2)OCCO3)nc(Nc2ccc3c(c2)OCCO3)c1N,[Pd],,,[H][H],,test
US04003909,COC(=O)Cl.Nc1ccc(-c2noc(-c3ccccc3)n2)cc1>>COC(=O)Nc1ccc(-c2noc(-c3ccccc3)n2)cc1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20100256092A1,COc1cccc(Oc2ccc(C=O)c(B3OC(C)(C)C(C)(C)O3)c2)c1>>COc1cccc(Oc2ccc3c(c2)B(O)OC3)c1,,C1CCOC1,CO,[BH4-].[Na+],,test
US20110172236A1,CC(C)(C1CCNC(=O)C1)S(=O)(=O)c1cccc(C(F)(F)F)c1.O=C(Cl)c1ccccc1>>CC(C)(C1CCN(C(=O)c2ccccc2)C(=O)C1)S(=O)(=O)c1cccc(C(F)(F)F)c1,,C1CCOC1,,O,,test
US20150094296A1,CC(C)[C@]1(C#N)CCN(c2ccnc(Nc3ccc(C(=O)OC(C)(C)C)c(OCC(F)(F)F)c3)n2)C1=O.Cl>>CC(C)[C@]1(C#N)CCN(c2ccnc(Nc3ccc(C(=O)O)c(OCC(F)(F)F)c3)n2)C1=O.Cl,,CCOC(C)=O,,,,test
US20110118248A1,CCc1cc(S(=O)(=O)Cl)ccc1Cl.Nc1cc(Cl)cnc1Br>>CCc1cc(S(=O)(=O)Nc2cc(Cl)cnc2Br)ccc1Cl,,c1ccncc1,,,,test
US20100311740A1,COc1ccc(CO)cc1.Cc1nc2c(Br)cc(Br)cn2c1C>>COc1ccc(COc2cc(Br)cn3c(C)c(C)nc23)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20050256140A1,Cn1c(C2=CCN(C(=O)OC(C)(C)C)CC2)nc(-c2ccccc2)c1-c1nc2c(N)ncnc2s1>>Cn1c(C2=CCNCC2)nc(-c2ccccc2)c1-c1nc2c(N)ncnc2s1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150038488A1,CNc1c(NC(=O)OC(C)(C)C)cc(Cl)nc1Cl>>CNc1c(N)cc(Cl)nc1Cl,,ClCCl,O=C(O)C(F)(F)F,,,test
US06100260,CC(C)(c1ccc(-c2ccccc2)c(F)c1)c1cc(N=C(N)N2CCOCC2)on1.CS(=O)(=O)O>>CC(C)(c1ccc(-c2ccccc2)c(F)c1)c1cc(N=C(N)N2CCOCC2)on1.CS(=O)(=O)O,,C1COCCO1,,,,test
US20100160309A1,CCCCOc1nccc2nc(C(C)(C)O)c3ccc(F)cc3c12>>CC(C)(O)c1nc2cc[nH]c(=O)c2c2cc(F)ccc12,,Br,CC(=O)O,,,test
US20080009482A1,CCOc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C(C)C)CCC(=O)N2C.CN1CCC(N)CC1>>CCOc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C(C)C)CCC(=O)N2C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140315888A1,CC(C)(C)OC(=O)N1CCNCC1.Cc1nc2c3cc(Cl)cnc3nc(Cl)n2n1>>Cc1nc2c3cc(Cl)cnc3nc(N3CCN(C(=O)OC(C)(C)C)CC3)n2n1,,CN(C)C=O,,,,test
US20160222033A1,CCOC(=O)C(=O)C(C)Br.NC(N)=S>>CCOC(=O)c1nc(N)sc1C,,C1COCCO1,,,,test
US04411839,O=C1CCC(=O)N1Br.O=c1ccn(Nc2c(Cl)cc(Cl)cc2Cl)c(=O)[nH]1>>O=c1[nH]c(=O)n(Nc2c(Cl)cc(Cl)cc2Cl)cc1Br,,CC(=O)O,,,,test
US04242507,CCOC(=O)C(C#N)=NOS(C)(=O)=O.O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1>>CCOC(=O)C(C#N)=NOC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1,,CCOC(C)=O,,CCN(CC)CC,,test
US20020016324A1,C=C1CC[C@@H]2[C@]3(C)COC(C)(C)O[C@@H]3CC[C@@]2(C)[C@@H]1C/C=C1/C(=O)OC[C@H]1OC(C)=O>>C=C1CCC2C(C)(CO)C(O)CCC2(C)C1C/C=C1\C(=O)OCC1OC(C)=O,,ClCCl,,CC(=O)O,,test
US20120264790A1,COC(=O)C1(NC(=O)c2ccc(OC)c(OCCc3cc(C)ccc3F)c2)CCCCCC1>>COc1ccc(C(=O)NC2(C(=O)O)CCCCCC2)cc1OCCc1cc(C)ccc1F,,C1COCCO1,,[Li+].[OH-],,test
US05646173,C[C@@H](O)CN.O=CCC1Cc2cc(F)ccc2C1=O>>C[C@@H](O)Cn1ccc2c1-c1ccc(F)cc1C2,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,O,,test
US20120142647A1,CC(C)N.CCCNc1nc(Cl)c2ccn(C)c2n1>>CCCNc1nc(NC(C)C)c2ccn(C)c2n1,,CCCCO,,O,O=C([O-])[O-].[K+].[K+],test
US20090312310A1,COc1ccc(N)cc1.O=Cc1ccc(Cl)nc1>>COc1ccc(/N=C/c2ccc(Cl)nc2)cc1,,CCO,,,,test
US04885373,NO.O=C(O)CCCc1ccc2c(c1)CCO2>>ON=C1CCCc2cc3c(cc21)OCC3,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20100021423A1,CO.COc1ccc(-c2cc(/C=C/c3ccc(NS(C)(=O)=O)cc3CBr)c(OC)c(C(C)(C)C)c2)c(=O)[nH]1>>COCc1cc(NS(C)(=O)=O)ccc1/C=C/c1cc(-c2ccc(OC)[nH]c2=O)cc(C(C)(C)C)c1OC,,CO,,C[O-].[Na+],,test
US20080194546A1,CC(C)Oc1ccc(-c2ccc3c(N4CCOC[C@@H]4C)nc(N4CCOC[C@@H]4C)nc3n2)cc1C#N.O=S(=O)(O)O>>CC(C)Oc1ccc(-c2ccc3c(N4CCOC[C@@H]4C)nc(N4CCOC[C@@H]4C)nc3n2)cc1C(N)=O,,O,,[Na+].[OH-],,test
US20160075696A1,CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.CN(C)C=O.C[C@H]1N[C@H]2C[C@@H]1C[C@H]2Oc1ccc(C(F)(F)F)cn1.F[P-](F)(F)(F)(F)F>>C[C@@H]1[C@H]2C[C@@H](Oc3ccc(C(F)(F)F)cn3)[C@H](C2)N1C(=O)c1ccc(F)cc1-n1nccn1,,O,,,,test
US04678500,CCCCN=C=O.COC(=O)c1cccc(S(=O)(=O)N(C)C)c1CS(N)(=O)=O>>CCCCNC(=O)NS(=O)(=O)Cc1c(C(=O)OC)cccc1S(=O)(=O)N(C)C,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070032478A1,CCn1nc(C)cc1C(=O)Nc1ccc(C(=O)c2ccc3c(c2)NC(=O)C3=CO)cc1.Nc1cccc(O)c1>>CCn1nc(C)cc1C(=O)Nc1ccc(C(=O)c2ccc3c(c2)NC(=O)C3=CNc2cccc(O)c2)cc1,,C1CCOC1,,,,test
US20080234255A1,CCOC(=O)CCN(Cc1ccccc1)c1nc(Cl)ncc1[N+](=O)[O-]>>O=C1CCN(Cc2ccccc2)c2nc(Cl)ncc2N1,,CCO,,Cl,,test
US20080280875A1,CCOC(=O)c1cc(Oc2ccc(C(=O)N(C)C)cc2)c2cc(CC)oc2c1>>CCc1cc2c(Oc3ccc(C(=O)N(C)C)cc3)cc(C(=O)O)cc2o1,,CO,O,[Li]O,,test
US20160152609A1,CCOC(=O)c1ncn2c1CCc1cc(OC)c([N+](=O)[O-])cc1-2.O=C1CCC(=O)N1Br>>CCOC(=O)c1nc(Br)n2c1CCc1cc(OC)c([N+](=O)[O-])cc1-2,,ClCCl,,O,,test
US20070083063A1,CC#N.CCCC(CCC)C(=O)O.CCO.CC[O-].CC[O-].[Mg+2]>>CCCC(CCC)C(=O)[O-].CCCC(CCC)C(=O)[O-].O.[Mg+2],,CCO,,,,test
US20160264518A1,COC(=O)/C=C/c1ccccc1NCc1nc2ccccc2[nH]1.COCCBr>>COCCn1c(CNc2ccccc2/C=C/C(=O)OC)nc2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020028836A1,Cc1ccc(C(=O)NC(N)C(Cl)(Cl)Cl)cc1.O=C=Nc1ccccc1>>Cc1ccc(C(=O)NC(NC(=O)Nc2ccccc2)C(Cl)(Cl)Cl)cc1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20040181062A1,CCOC(OCC)OCC.Cl.Nc1ccc2c(c1)nc(/C=C/c1ccccc1)n2-c1ccccn1>>CNc1ccc2c(c1)nc(/C=C/c1ccccc1)n2-c1ccccn1.Cl,,CCO,CO,[BH4-].[Na+],,test
US20100016282A1,C[C@@H]1NCCN(CCCN2CCCCC2)C1=O.O=C=Nc1cccc(Cl)c1>>C[C@H]1C(=O)N(CCCN2CCCCC2)CCN1C(=O)Nc1cccc(Cl)c1,,CN(C)C=O,,CN1CCOCC1,,test
US20070244159A1,CC(C)(C)OC(=O)N1CCC(c2cc3cc(N)ccc3[nH]2)CC1.O=C(Cl)C1(c2ccc3c(c2)OCO3)CC1>>CC(C)(C)OC(=O)N1CCC(c2cc3cc(NC(=O)C4(c5ccc6c(c5)OCO6)CC4)ccc3[nH]2)CC1,,ClCCl,,CCN(CC)CC,,test
US20110144105A1,CS(=O)(=O)c1ccc(B(O)O)cc1.Cc1ccc(S(=O)(=O)OC(=CC2CCCC2)c2cc3cc(C4COC(C)(C)O4)cnc3n2S(=O)(=O)c2ccccc2)cc1>>CC1(C)OCC(c2cnc3c(c2)cc(C(=CC2CCCC2)c2ccc(S(C)(=O)=O)cc2)n3S(=O)(=O)c2ccccc2)O1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20050215605A1,CC(C)(C)OC(=O)N1CCSC1C(=O)O.N[C@@H](CCO)c1ccccc1>>CC(C)(C)OC(=O)N1CCSC1C(=O)N[C@@H](CCO)c1ccccc1,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20100048636A1,CC(C)(C)OC(=O)N1CCC[C@@H](C(OCC(N)=O)c2cccc(Cl)c2F)C1>>NC(=O)CO[C@@H](c1cccc(Cl)c1F)C1CCCNC1,,ClCCl,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],,test
US20160184318A1,C/C(N)=N/OC(=O)CN1CCN(C(=O)/C=C/c2ccc(Cl)cc2Cn2nnc(C)n2)[C@H](C)C1>>Cc1noc(CN2CCN(C(=O)/C=C/c3ccc(Cl)cc3Cn3nnc(C)n3)[C@H](C)C2)n1,,Cc1ccccc1,,,,test
US20050171180A1,CCC(CC)C(O)c1ccnn1-c1ccc(OC)cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CCC(CC)C(N=[N+]=[N-])c1ccnn1-c1ccc(OC)cc1,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090291978A1,CC(C)(C)OC(=O)N(Cc1cccc([N+](=O)[O-])c1)[C@H](C(=O)OC1CCCC1)c1ccccc1>>CC(C)(C)OC(=O)N(Cc1cccc(N)c1)[C@H](C(=O)OC1CCCC1)c1ccccc1,[Pd],CCO,,,,test
US20140315888A1,Clc1cnc2nc(Cl)c(Cl)nc2c1.NN>>NNc1nc2ncc(Cl)cc2nc1Cl,,CCO,,O,,test
US20150376169A1,CCc1ccc(N)nc1.CI>>CCc1ccc(NC)nc1,,C1CCOC1,,O,[Li]CCCC,test
US20020009748A1,NNc1cc(C2CNCCN2Cc2ccccc2)nc(C2CNCCN2Cc2ccccc2)n1>>Nc1cc(C2CNCCN2Cc2ccccc2)nc(C2CNCCN2Cc2ccccc2)n1,[Ni],CCOC(C)=O,,,,test
US20150166492A1,Nc1ccc(Cl)cc1O.O=C(CBr)c1ccc(-c2ccccc2)cc1>>Clc1ccc2c(c1)OCC(c1ccc(-c3ccccc3)cc1)=N2,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US03966930,CC(=O)Cl.Fc1ccc2c(c1)Sc1ccccc1N2>>CC(=O)N1c2ccccc2Sc2cc(F)ccc21,,c1ccccc1,,,,test
US06093838,CCOC(=O)c1ccc(N(CC)c2ccc3c(c2)C(C)(C)OC3(C)C)cc1>>CCN(c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)OC2(C)C,,CCO,,[Na+].[OH-],,test
US20090022664A1,C1=CCNC1.COC(=O)CCC(=O)Cl>>COC(=O)CCC(=O)N1CC=CC1,,ClCCl,,CCN(CC)CC,,test
US20100022544A1,CC(=O)OCC(=O)Cl.CC(C)(C)[Si](OCC1CCNCC1)(c1ccccc1)c1ccccc1>>CC(=O)OCC(=O)N1CCC(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)CC1,,ClCCl,,CCN(CC)CC,,test
US20100094000A1,Cc1ccc(Cn2nc(C)cc2-c2ccc(F)cc2)cc1.O=C1CCC(=O)N1Br>>Cc1ccc(Cn2nc(C)c(Br)c2-c2ccc(F)cc2)cc1,,CC#N,,,,test
US20150210715A1,COC(=O)c1c(C)nc2sc(C)cn12>>Cc1cn2c(C(=O)O)c(C)nc2s1,,CCO,,[Li+].[OH-],,test
US20050209290A1,FC(F)(F)Oc1ccc(C=Cc2nc(CCl)co2)cc1.Oc1ccc(COCCn2ccnn2)cc1>>FC(F)(F)Oc1ccc(/C=C/c2nc(COc3ccc(COCCn4ccnn4)cc3)co2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20050165063A1,CC(C)(C)OC(=O)NCCCCNS(=O)(=O)c1ccc(CNCc2ncc[nH]2)cc1.Cn1ccnc1C=O>>Cn1ccnc1CN(Cc1ccc(S(=O)(=O)NCCCCNC(=O)OC(C)(C)C)cc1)Cc1ncc[nH]1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20090156593A1,CN(C)C1(c2ccc3c(c2)OCO3)CCC2(CC1)OCCO2>>CN(C)C1(c2ccc3c(c2)OCO3)CCC(=O)CC1,,Cl,,,,test
US20100331315A1,CC1=NNC(=O)C1.O=Cc1ccc(-c2cccc(C(=O)O)c2)o1>>CC1=NNC(=O)C1=Cc1ccc(-c2cccc(C(=O)O)c2)o1,,CCO,,C1CCNCC1,,test
US20140194431A1,CC(C)N(CCO[Si](C)(C)C(C)(C)C)C(=O)c1[nH]c(Cc2c(Cl)cccc2Cl)nc(=O)c1OCc1ccccc1>>CC(C)N(CCO)C(=O)c1[nH]c(Cc2c(Cl)cccc2Cl)nc(=O)c1OCc1ccccc1,,C1CCOC1,,Cl,,test
US20150252067A1,Nc1ccccc1-c1ccccn1.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=[N+]([O-])C1(c2ccccn2)C=CC=CC1S(=O)(=O)Nc1ccccc1,,ClCCl,,O,c1ccncc1,test
US05296482,CNC(=O)CC1Cc2cc(OC)c(OC)cc2C1>>CNCCC1Cc2cc(OC)c(OC)cc2C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20160194304A1,Cc1c(C(=O)N(C)c2ccc(OCc3ccccc3)cc2)cc(-c2cc3c(cc2C(=O)N2Cc4ccccc4C[C@H]2CN(C)C)CN(C(=O)Cc2ccccc2)CC3)n1C>>Cc1c(C(=O)N(C)c2ccc(O)cc2)cc(-c2cc3c(cc2C(=O)N2Cc4ccccc4C[C@H]2CN(C)C)CN(C(=O)Cc2ccccc2)CC3)n1C,[Pd],CCO,,,,test
US20050107339A1,CCOc1cc(C(O)c2ccc(OC)c(OCC)c2)ccc1OC>>CCOc1cc(C(=O)c2ccc(OC)c(OCC)c2)ccc1OC,O=[Mn]=O,ClCCl,,,,test
US20160185785A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.[Li]CCCC>>CC=C1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,,,test
US20120220603A1,CC(C)(N)CNC(=O)OC(C)(C)C.COC(=O)CCl>>COC(=O)CNC(C)(C)CNC(=O)OC(C)(C)C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060293337A1,C=CC(=O)OCC.NC1CN(c2ccc3c(C(=O)NCC4CCCCC4)c(Cl)ccc3n2)C1>>O=C(O)CCNC1CN(c2ccc3c(C(=O)NCCC4CCCCC4)c(Cl)ccc3n2)C1,,CO,,Cl,[Na+].[OH-],test
US20140309193A1,CC(C)(C)OC(=O)C(C)(C)COCCOCCOP(=O)(OCc1ccccc1)OCc1ccccc1>>CC(C)(COCCOCCOP(=O)(OCc1ccccc1)OCc1ccccc1)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080039455A1,BrBr.Clc1ccn2nccc2n1>>Clc1ccn2ncc(Br)c2n1,,CC(=O)O,,,,test
US20070185101A1,CCO.O=C(O)C1Cc2ccccc2CN1>>CCOC(=O)C1Cc2ccccc2CN1,,CCO,Cl,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US04535089,CC(C)CC(=O)CNC(=O)c1ccc(F)cc1.CCOC(=O)CBr>>CCOC(=O)CC(NC(=O)c1ccc(F)cc1)C(=O)CC(C)C,,CS(C)=O,,[K+].[OH-],,test
US20150232481A1,C=CCCc1cccc(COCc2cc3nc(C)c([C@H](OC(C)(C)C)C(=O)OCC)c(N4CCC(C)(OCC=C)CC4)n3n2)c1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc3nn2c1N1CCC(C)(CC1)OCCCCCc1cccc(c1)COC3,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,ClCCl,,[BH4-].[Na+],,test
US20100196321A1,CCN(C(C)C)C(C)C.CN(C)C=O.COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)NS(=O)(=O)C6CC6)C[C@H]5C=CCCCCC[C@H](N)C(=O)N4C3)cc(-c3nc(C4CC4)cs3)nc2c1Cl.ClCCl.O=C(n1ccnc1)n1ccnc1>>C=C1CCN(C(=O)N[C@H]2CCCCCC=C[C@@H]3C[C@@]3(C(=O)NS(=O)(=O)C3CC3)NC(=O)[C@@H]3C[C@@H](Oc4cc(-c5nc(C6CC6)cs5)nc5c(Cl)c(OC)ccc45)CN3C2=O)CC1,,CN(C)C=O,ClCCl,Cl,,test
US20050090483A1,Brc1cncc2ccoc12.N#C[Cu]C#N>>N#Cc1cncc2ccoc12,I[Cu]I,CCOCC,,CN(C)C=O,,test
US20100168385A1,CC(C)[C@@H](CO)NC(=O)OCc1ccccc1>>CC(C)[C@H](N)CO.O=C=O,[Pd],CO,,[H][H],,test
US05348965,C=C[Mg]Br.O=C1c2ccccc2CCc2ccccc21>>C=CC1(O)c2ccccc2CCc2ccccc21,,C1CCOC1,O,CCOCC,[Cl-].[NH4+],test
US20140323470A1,CS(=O)(=O)Cl.C[C@H]1CCC[C@@H](C)N1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4cccc(OCCO)c4)c4ccccc43)cn12>>C[C@H]1CCC[C@@H](C)N1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4cccc(OCCOS(C)(=O)=O)c4)c4ccccc43)cn12,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150210641A1,C1CCC(N2CCNCC2)C1.COc1cc(F)ccc1-c1ccc(C(OS(C)(=O)=O)c2ccncc2)cc1>>COc1cc(F)ccc1-c1ccc(C(c2ccncc2)N2CCN(C3CCCC3)CC2)cc1,,ClCCl,,,,test
US20120219522A1,Clc1ccnc2cc(OCc3ccccc3)ccc12.O=[N+]([O-])c1ccc(O)cc1>>O=[N+]([O-])c1ccc(Oc2ccnc3cc(OCc4ccccc4)ccc23)cc1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,ClCCl,test
US20100075947A1,Nc1ccc(F)cc1.O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccccc1>>O=S(=O)(Nc1nc2ccccc2nc1Nc1ccc(F)cc1)c1ccccc1,,CO,,CC(=O)N(C)C,,test
US20110003815A1,C=O.O=C(NC1CCNCC1)c1ccc(C2(c3ccc(OCc4ccccn4)cc3)CC3CCC2C3)cc1>>CN1CCC(NC(=O)c2ccc(C3(c4ccc(OCc5ccccn5)cc4)CC4CCC3C4)cc2)CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20160272595A1,Cc1ccc(C(=O)O)c(N)c1.II>>Cc1cc(N)c(C(=O)O)cc1I,,CCCCO,,OO,,test
US20160060225A1,CC(Br)C(=O)c1ccccc1.O=C(O)Cc1c(F)cccc1F>>CC(OC(=O)Cc1c(F)cccc1F)C(=O)c1ccccc1,,CC#N,,CCN(CC)CC,,test
US20120040020A1,CC(C)(C)OC(=O)Nc1ncc(Br)nc1-c1cc2ccccc2o1.CCS(=O)(=O)N1CCNCC1>>CCS(=O)(=O)N1CCN(c2cnc(N)c(-c3cc4ccccc4o3)n2)CC1,,COCCO,,C1COCCO1,Cl,test
US06380238B1,CC1CO1.Clc1ccc2cc[nH]c2c1>>CC(O)Cn1ccc2ccc(Cl)cc21,,C1CCOC1,,[H-].[Na+],,test
US20160207883A1,C=CCBr.OC1CCOCC1>>C=CCOC1CCOCC1,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20070037846A1,CCCOc1ccc(C=O)c(C)c1C.O=C1CC(=O)N(c2ccccc2Cl)N1>>CCCOc1ccc(C=C2C(=O)NN(c3ccccc3Cl)C2=O)c(C)c1C,,CCO,,,,test
US05208247,CCCCCCCCCCCCCCOc1ccc(CC(=O)Cl)cc1.NCc1ccccn1>>CCCCCCCCCCCCCCOc1ccc(CC(=O)NCc2ccccn2)cc1,,ClC(Cl)Cl,ClCCl,c1ccncc1,,test
US20050165000A1,COC(=O)c1nc(N2CCCCS2(=O)=O)c2cccnc2c1O>>O=C(O)c1nc(N2CCCCS2(=O)=O)c2cccnc2c1O,,CO,,Cl,[Li+].[OH-],test
US20160016948A1,CC(C)n1ccc2cnc(Cl)cc21.CN(C)C=O>>CC(C)n1cc(C=O)c2cnc(Cl)cc21,,CN(C)C=O,,O=P(Cl)(Cl)Cl,O=C([O-])O.[Na+],test
US20090253736A1,CC(C)(C)C#Cc1cc(Cl)ncc1NC(=O)OC(C)(C)C>>CC(C)(C)c1cc2cc(Cl)ncc2[nH]1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06326359B1,CN(C)CCO.COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(COS(C)(=O)=O)nc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C>>COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(COCCN(C)C)nc32)[C@H](O)[C@@H]1O,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US04224326,Nc1cccc2cccc(N)c12.O=C(F)c1ccc(OC(F)(F)F)cc1>>F.FC(F)(F)Oc1ccc(C2=Nc3cccc4cccc(c34)N2)cc1,,Cc1ccccc1,,,,test
US20040097550A1,NNc1ccccc1.O=C=Nc1ccc(Cl)cc1>>O=C(NNc1ccccc1)Nc1ccc(Cl)cc1,,C1CCOC1,,,,test
US20160009712A1,CNc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.COC(=O)Cl>>COC(=O)N(C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070208001A1,O=C(O)C1(c2ccc(Cl)cc2)CC1>>OCC1(c2ccc(Cl)cc2)CC1,,C1CCOC1,,B,,test
US20120270838A1,C=CCCOc1cc(C(=O)O)ccc1C(F)(F)F.C=CCOCCN(C)C(=O)c1ccc(CCS(=O)(=O)N2CCC(N)(C(N)=O)CC2)c(C)c1>>C=CCCOc1cc(C(=O)NC2(C(N)=O)CCN(S(=O)(=O)CCc3ccc(C(=O)N(C)CCOCC=C)cc3C)CC2)ccc1C(F)(F)F,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150232465A1,C[C@@H](CO)Nc1cnc(Br)cc1[N+](=O)[O-]>>C[C@@H](CO)Nc1cnc(Br)cc1N,[Fe],CCO,O,[Cl-].[NH4+],,test
US20140187553A1,Cc1ccc(S(=O)(=O)n2cc(-c3cncc(NC4CC4)n3)c3cc(-c4nnc(N)s4)ccc32)cc1>>Nc1nnc(-c2ccc3[nH]cc(-c4cncc(NC5CC5)n4)c3c2)s1,,C1COCCO1,,[K+].[OH-],,test
US03939267,CC(=O)Nc1ccc(Oc2c(N)cc(C(=O)O)cc2S(N)(=O)=O)cc1.ClCc1ccccc1>>CC(=O)Nc1ccc(Oc2c(NCc3ccccc3)cc(C(=O)O)cc2S(N)(=O)=O)cc1,,O,,[Na+].[OH-],,test
US20150158863A1,O=C1OCCC1Br.Oc1ccc(OC(F)(F)F)cc1>>O=C1OCCC1Oc1ccc(OC(F)(F)F)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090209578A1,CC(=O)C[C@H](NC(=O)OC(C)(C)C)c1ccccc1>>CC(=O)C[C@H](N)c1ccccc1,,ClCCl,,Cl,,test
US20060252785A1,CC(C)(C)N1C(=O)CC(=O)N1Cc1ccc(F)cc1.O=S1(=O)N=C(Cl)c2ccccc21>>CC(C)(C)n1c(O)c(C2=NS(=O)(=O)c3ccccc32)c(=O)n1Cc1ccc(F)cc1,,C1CCOC1,,[H-].[Na+],,test
US20010021714A1,CC(C)c1sc2ccccc2c1S(=O)(=O)Cl.Cc1noc(N)c1Br>>Cc1noc(NS(=O)(=O)c2c(C(C)C)sc3ccccc23)c1Br,,C1CCOC1,,[H-].[Na+],,test
US04550103,OCCNCC1CCN(Cc2ccccc2)C1>>OCCNCC1CCNC1,[Pd],CO,,[H][H],,test
US20020082280A1,CCCC(=O)Cl.Nc1ccc(C(=O)NS(=O)(=O)c2ccccc2)cc1NCc1ccc(-c2ccccc2)cc1>>CCCC(=O)Nc1ccc(C(=O)NS(=O)(=O)c2ccccc2)cc1NCc1ccc(-c2ccccc2)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20020052497A1,CCOc1cncc(/C=C/CC(C)N(C)C(=O)OC(C)(C)C)c1>>CCOc1cncc(/C=C/CC(C)NC)c1,,COc1ccccc1,,O=C(O)C(F)(F)F,,test
US20100184770A1,CO.COC(=O)C(C)CN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O.[OH-]>>CC(CN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O)C(=O)O.O=CO,,CO,,Cl,,test
US20090176850A1,Br[Mg]c1ccccc1.CON(C)C(=O)CCc1cccc(Br)c1>>O=C(CCc1cccc(Br)c1)c1ccccc1,,C1CCOC1,,,,test
US20120316193A1,C1CCNCC1.Cc1nn(-c2ccc(Cl)cc2)c(C)c1C(=O)CCl>>Cc1nn(-c2ccc(Cl)cc2)c(C)c1C(=O)CN1CCCCC1,,CCOC(C)=O,,,,test
US20080039459A1,BrBr.CC(=O)c1cc2nc(Cl)nc(N3CCOCC3)c2s1>>O=C(CBr)c1cc2nc(Cl)nc(N3CCOCC3)c2s1,,ClC(Cl)Cl,,Br,CC(=O)O,test
US20110086854A1,CC(C)(C)CC1CNC(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.COC(=O)c1ccccc1N=C=O>>COC(=O)c1ccccc1NC(=O)N1C[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F,,ClCCl,,,,test
US20140336108A1,Cc1ccoc1C(=O)Nc1cccc(Oc2ccnc3cc(C(=O)O)sc23)c1.OCCCBr>>Cc1ccoc1C(=O)Nc1cccc(Oc2ccnc3cc(C(=O)OCCCO)sc23)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090192203A1,O=S(Cl)Cl.OCc1nc(-c2ccc(-c3ccccc3)cc2)cs1>>ClCc1nc(-c2ccc(-c3ccccc3)cc2)cs1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20120214803A1,NS(N)(=O)=O.Nc1c(Nc2ccccc2)ccc2cccnc12>>O=S1(=O)Nc2ccc3cccnc3c2N1c1ccccc1,,c1ccncc1,,,,test
US20100305067A1,CCN=C=O.Cc1cc2sc(N)nc2cc1O>>CCNC(=O)Nc1nc2cc(O)c(C)cc2s1,,C1COCCO1,,,,test
US20080051399A1,C[C@@H]1C[C@H](O)c2ncnc(N3CCN(C(=O)[C@H](CN(CC4CC4)C(=O)OC(C)(C)C)c4ccc(Cl)cc4)CC3)c21>>C[C@@H]1C[C@H](O)c2ncnc(N3CCN(C(=O)[C@H](CNCC4CC4)c4ccc(Cl)cc4)CC3)c21,,C1COCCO1,,Cl,,test
US20150051171A1,Cn1nnn(-c2cccc([N+](=O)[O-])c2CBr)c1=O.Oc1ccn(-c2ccc(Cl)cc2)n1>>Cn1nnn(-c2cccc([N+](=O)[O-])c2COc2ccn(-c3ccc(Cl)cc3)n2)c1=O,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20080234270A1,CCI.Cc1cc(C(=O)Nc2ccc(S(N)(=O)=O)cc2)c(C)n1-c1ccccc1C(F)(F)F>>CCNS(=O)(=O)c1ccc(NC(=O)c2cc(C)n(-c3ccccc3C(F)(F)F)c2C)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110275637A1,C[C@H]1CNC[C@@H](C)O1.O=C(OCCc1ccncc1)Oc1ccc([N+](=O)[O-])cc1>>C[C@H]1CN(C(=O)OCCc2ccncc2)C[C@@H](C)O1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04209521,O=C(NC(=O)c1ccccc1)NC1CCN(Cc2c[nH]c3ccccc23)CC1>>NC(=O)NC1CCN(Cc2c[nH]c3ccccc23)CC1,,CO,O,[Na+].[OH-],,test
US20150051211A1,CCOC(=O)c1cccc(Oc2n[nH]c(=O)c3ccccc23)c1>>O=C(O)c1cccc(Oc2n[nH]c(=O)c3ccccc23)c1,,[K+],[OH-],Cl,,test
US20020038004A1,CO.O=C(O)CCCCCNC(=O)c1ccc(Br)c(Br)c1>>COC(=O)CCCCCNC(=O)c1ccc(Br)c(Br)c1,,CO,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US20150191478A1,C[Mg]Br.O=Cc1cc2cncc(I)c2o1>>CC(O)c1cc2cncc(I)c2o1,,C1CCOC1,,[Cl-].[NH4+],,test
US04895842,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NC1CCCCC1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NC1CCCCC1,[Pd],CCO,,C1=CCCCC1,,test
US20040019016A1,BrP(Br)Br.OCc1ccc(OCc2ccccc2)c(Cl)c1>>Clc1cc(CBr)ccc1OCc1ccccc1,,CCOCC,ClCCl,,,test
US05312828,CCCCc1ncc(/C=C(/CO)Cc2ccccc2)n1Cc1ccccc1Cl.COC(=O)CBr>>CCCCc1ncc(C/C=C/OC(Cc2ccccc2)C(=O)O)n1Cc1ccccc1Cl,,COCCOC,,[H-].[Na+],,test
US20090012129A1,CCCCCNC(=O)N(C)c1cccc(-c2ccc(/C=C(\CC)C(=O)OCC)cc2)c1>>CCCCCNC(=O)N(C)c1cccc(-c2ccc(/C=C(\CC)C(=O)O)cc2)c1,,CCO,CCOCC,[Na+].[OH-],,test
US20110130398A1,CC(C)(C)CC1NC(C(=O)Nc2ccc(C#N)cc2F)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12.OO>>CC(C)(C)CC1NC(C(=O)Nc2ccc(C(N)=O)cc2F)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12,,CS(C)=O,,[Na+].[OH-],,test
US20160108027A1,CC1(CC=O)OCCN(Cc2ccccc2)C1=O>>CC1(CCO)OCCN(Cc2ccccc2)C1=O,,CO,,O,[BH4-].[Na+],test
US20070054935A1,C[Mg]Br.N#Cc1cccc(-c2ccncc2C=O)c1>>CC(O)c1cnccc1-c1cccc(C#N)c1,,C1CCOC1,,,,test
US05932595,O=C(O)C=C1CCCC1.Sc1ccc(Oc2ccccc2)cc1>>O=C(O)CC1(Sc2ccc(Oc3ccccc3)cc2)CCCC1,,CCOC(C)=O,,C1CCNCC1,,test
US20070054897A1,C1CCC(NC2CCCCC2)CC1.Nc1nccs1.O=C(n1ccnc1)n1ccnc1>>O=C(Nc1nccs1)N(C1CCCCC1)C1CCCCC1,,CCOC(C)=O,ClCCl,,,test
US20090137561A1,COC(=O)c1ccc(-c2cc(OC)ccc2F)c(C(C)C(C)C)c1>>COc1ccc(F)c(-c2ccc(CO)cc2C(C)C(C)C)c1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20120252796A1,CCOC(=O)C(Cc1nc(-c2ccccc2)oc1C)C(=O)OCC>>Cc1oc(-c2ccccc2)nc1CC(CO)CO,,CCO,,[BH4-].[Na+],,test
US20160016966A1,CC1(C)OB(c2ccnc(NCc3ccccn3)c2)OC1(C)C.Cn1cc(Br)c2oc(CN3CCCN(C(=O)OC(C)(C)C)CC3)cc2c1=O>>Cn1cc(-c2ccnc(NCc3ccccn3)c2)c2oc(CN3CCCN(C(=O)OC(C)(C)C)CC3)cc2c1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20030027823A1,ClCCBr.O=c1[nH]c2ccccc2n1CCOC1CCCCO1>>O=c1n(CCCl)c2ccccc2n1CCOC1CCCCO1,,O,,CN(C)C=O,,test
US20150031674A1,CC(C)(C)OC(=O)N1CCS(=O)(=O)CC1.CCOC(=O)CBr>>CCOC(=O)CC1CN(C(=O)OC(C)(C)C)CCS1(=O)=O,,C1CCOC1,CCOC(C)=O,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20150119435A1,CS(=O)(=O)OCCCCN=[N+]=[N-].OCCOCCOCCOCCOC12CC3CC(CC(C3)C1)C2>>[N-]=[N+]=NCCCCOCCOCCOCCOCCOC12CC3CC(CC(C3)C1)C2,,C1CCOC1,,CN(C)C=O,[H-].[Na+],test
US20160083400A1,COC(=O)c1ccnc(C(C)C)c1N>>CC(C)c1nccc(C(=O)O)c1N,,C1CCOC1,O,[Li+].[OH-],,test
US04741767,CC(C)C1(C)C(=O)N=C2c3ncccc3C(=O)N21.O>>CC(C)C1(C)C(=O)NC2(O)c3ncccc3C(=O)N21,,O,,CC(C)=O,,test
US03991065,CCO.NO.O=c1ccc2ccccc2[nH]1>>Cc1cnc2c(c1)CCCC2=NO,,O,,Cl,[Na+].[OH-],test
US20050176701A1,COC(=O)CC(C)=O.COc1ccc(CCC(=O)C2CCCC2)c(OC)c1>>COc1ccc(CCC2(C3CCCC3)CC(=O)CC(=O)O2)c(OC)c1,,C1CCOC1,,[Li]CCCC,[H-].[Na+],test
US20100331326A1,Brc1ccccc1.Cc1ccncc1N1CCNC1=O>>Cc1ccncc1N1CCN(c2ccccc2)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US06551682B1,COc1nc(C)nc(F)c1C(F)(F)F.NN>>COc1nc(C)nc(NN)c1C(F)(F)F,,CCO,,O,,test
US05334606,CCOC(=O)CC(C(=O)OCC)C(=O)OCC.CN(C)Cc1c[nH]c2ccccc12>>O=C(O)CC(Cc1c[nH]c2ccccc12)(C(=O)O)C(=O)O,,Cc1ccccc1,,[Na],,test
US20110086834A1,C=C(OC)c1cn(C)cn1>>CC(=O)c1cn(C)cn1,,CC#N,O,,,test
US20090253736A1,CC(C)(C)c1cc2cc([N+](=O)[O-])cnc2[nH]1>>CC(C)(C)c1cc2cc(N)cnc2[nH]1,[Ni],CO,,,,test
US05380879,COC(=O)CC/C(C)=C/Cc1c(N)c2c(c(C)c1OC)COC2=O.CS(=O)(=O)OS(C)(=O)=O>>COC(=O)CC/C(C)=C/Cc1c(NS(C)(=O)=O)c2c(c(C)c1OC)COC2=O,,ClCCl,,c1ccncc1,,test
US20120040897A1,CCOC(=O)C1(COC)CCN(C(=O)OC(C)(C)C)CC1>>COCC1(C(=O)O)CCN(C(=O)OC(C)(C)C)CC1,,CO,,[Na+].[OH-],,test
US04071621,CCSCCNCC(=O)OC(C)(C)C.COc1cc2ccc(S(=O)(=O)N[C@@H](CCCNC(=N)N)C(=O)Cl)cc2cc1OC.N#N>>CCSCCN(CC(=O)OC(C)(C)C)C(=O)[C@H](CCCNC(=N)N)NS(=O)(=O)c1ccc2cc(OC)c(OC)cc2c1.N#N,,ClC(Cl)Cl,,Cl,,test
US20090042964A1,CC(C)I.Cc1cc(C#Cc2ccc(F)c(O)c2)ccc1OC(F)F>>Cc1cc(C#Cc2ccc(F)c(OC(C)C)c2)ccc1OC(F)F,,CCC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130244929A1,CCCc1ccc(-c2ccc(C(=O)NCCC(=O)OC)cc2)cc1>>CCCc1ccc(-c2ccc(C(=O)NCCC(=O)O)cc2)cc1,,C1CCOC1,CO,[Li+].[OH-],,test
US20150368260A1,CCN.O=C(Cl)c1cncc(Cl)n1>>CCNC(=O)c1cncc(Cl)n1,,C1CCOC1,,CCN(CC)CC,,test
US20080045550A1,CC(C)(C)OC(=O)NC1CCNCC1.CC(C)Oc1cc(C=O)cc(OC(C)C)c1>>CC(C)Oc1cc(CN2CCC(NC(=O)OC(C)(C)C)CC2)cc(OC(C)C)c1,,CCO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20090099187A1,COc1ccc(S(=O)(=O)Nc2cnc3ccccc3c2)c2c1C[C@@H](NC(=O)C(F)(F)F)CC2>>COc1ccc(S(=O)(=O)Nc2cnc3ccccc3c2)c2c1C[C@@H](N)CC2,,CO,O,N,,test
US20120077828A1,CCn1nc(I)c2c(N)ncnc21.Cc1cccc(CC(=O)N2CCc3cc(B4OC(C)(C)C(C)(C)O4)ccc32)c1>>CCn1nc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(C)c2)c2c(N)ncnc21,,O,,C1COCCO1,O=C([O-])O.[Na+],test
US20100286112A1,CC(C)c1noc(N2CCC(CCCOc3ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)N4CCSC4)cc3)CC2)n1>>CC(C)c1noc(N2CCC(CCCOc3ccc(C[C@H](N)C(=O)N4CCSC4)cc3)CC2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110098480A1,CC(C)C[Mg]Br.O=Cc1ccc(C(F)(F)F)cc1F>>CC(C)CC(O)c1ccc(C(F)(F)F)cc1F,,C1CCOC1,CCOCC,Cl,[Cl-].[NH4+],test
US06924300B2,CCN=C=NCCCN(C)C.Cc1oc(-c2ccccc2)nc1COc1ccc(CO/N=C(\CC(=O)O)c2ccccc2)cc1>>Cc1oc(-c2ccccc2)nc1COc1ccc(CO/N=C(\CC(N)=O)c2ccccc2)cc1,,O,,CN(C)C=O,Cl,test
US20130261106A1,Cc1cc([N+](=O)[O-])c(OC(C)C)cc1N1CCN(C)CC1>>Cc1cc(N)c(OC(C)C)cc1N1CCN(C)CC1,[Pd],CO,,O=C[O-].[NH4+],,test
US05292452,Fc1ccc(-c2ccc(C3CCC(C4OCCCO4)CC3)cn2)cc1F>>O=C[C@@H]1CC[C@@H](c2ccc(-c3ccc(F)c(F)c3)nc2)CC1,,O=CO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20060009443A1,NN=C1NCCCCN1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>FC(F)(F)c1nnc2n1CCCCN2,,ClCCl,,I,,test
US20150018546A1,Cc1ncnc2c1c(OS(=O)(=O)C(F)(F)F)cc(=O)n2OCc1ccccc1.NCc1nc2ccccc2[nH]1>>Cc1ncnc2c1c(NCc1nc3ccccc3[nH]1)cc(=O)n2OCc1ccccc1,,C1COCCO1,,CCN(CC)CC,,test
US05965491,CC(=O)c1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1S(C)=O.CNO>>CC(c1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1S(C)=O)=[N+](C)[O-],,CO,,Cl,c1ccncc1,test
US20120277185A1,CCc1cc(C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)cc(C)c1NC(=O)c1ccc2c(ccc(C#N)[n+]2[O-])c1.O=P(Br)(Br)Br>>CCc1cc(C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)cc(C)c1NC(=O)c1ccc2nc(C#N)cc(Br)c2c1,,CC#N,,O=C([O-])O.[Na+],,test
US05321037,Cc1c(-c2ccccc2)on(CC(O)CN2CCOCC2)c1=O.Cl>>Cc1c(-c2ccccc2)on(CC(O)CN2CCOCC2)c1=O.Cl,,C1COCCO1,CCO,,,test
US05252735,ClCc1ccccn1.O=c1cc(-c2ccc(O)cc2)oc(N2CCOCC2)c1>>O=c1cc(-c2ccc(OCc3ccccn3)cc2)oc(N2CCOCC2)c1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20150025070A1,CC(C)(C)OC(=O)CBr.COC(=O)C1CCNCC1>>COC(=O)C1CCN(CC(=O)OC(C)(C)C)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20120094958A1,CCOP(OCC)OCC.Clc1ccc2cccc(-c3cccc4ccccc34)c2n1>>CCOP(=O)(OCC)c1ccc2cccc(-c3cccc4ccccc34)c2n1,Cl[Ni]Cl,ClCCl,,,,test
US20130345419A1,COc1ccc(OCC(=O)CNC(=O)[C@@H]2CCCN2C(=O)OC(C)(C)C)cc1OC>>COc1ccc(OCc2cnc([C@@H]3CCCN3C(=O)OC(C)(C)C)o2)cc1OC,,Cc1ccccc1,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US20050070521A1,BrCc1ccccc1.O=C(CCOCCc1ccc2sccc2c1)N1CC(O)C1>>O=C(CCOCCc1ccc2sccc2c1)N1CC(OCc2ccccc2)C1,O=[Ag-],CN(C)C=O,,,,test
US20150218141A1,COc1cccc(C2CCCNC2)c1.FC(F)(F)[C@@H]1CO1>>COc1cccc(C2CCCN(C[C@H](O)C(F)(F)F)C2)c1,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20130310380A1,CC1CCCN(C(=N)N)C1.Cc1occc1C(=O)C(=CN(C)C)c1ccccn1>>Cc1occc1-c1nc(N2CCCC(C)C2)ncc1-c1ccccn1,,CCO,O,Cl,CC(C)(C)[O-].[K+],test
US20090156642A1,CCOC(=O)c1cc(O)n(-c2cc(F)ccc2Cl)n1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1cc(OS(=O)(=O)C(F)(F)F)n(-c2cc(F)ccc2Cl)n1,,C1CCOC1,,CCN(CC)CC,O,test
US20130281431A1,Cc1ncc(B2OC(C)(C)C(C)(C)O2)cn1.Clc1cc(Cl)ncn1>>Cc1ncc(-c2cc(Cl)ncn2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,[Cs+].[F-],test
US06268444B1,CC1=C(N2CCCC2)c2ccccc2C1.[Li]CCCC>>[Li]C1(N2CCCC2)C(C)=Cc2ccccc21,,CCCCCC,,,,test
US20060293337A1,CCCCC(CC)COC(=O)Cl.NC(=NO)C1CCN(c2ccc3c(NC(=O)CC4CCCCC4)c(Cl)ccc3n2)CC1>>O=C(CC1CCCCC1)Nc1c(Cl)ccc2nc(N3CCC(c4noc(=O)[nH]4)CC3)ccc12,,ClCCl,,c1ccncc1,,test
US20020120007A1,COc1ccc(NC(=O)c2ccccc2N)cc1.O=C(O)c1ccc(-c2ccncc2)cc1.O=S(Cl)Cl>>COc1ccc(NC(=O)c2ccccc2NC(=O)c2ccc(-c3ccncc3)cc2)cc1.Cl,,Cc1ccccc1,c1ccncc1,,,test
US20070037836A1,O=[Cr](=O)=O.OCCCc1ccc(Br)cc1OC(F)(F)F>>O=C(O)CCc1ccc(Br)cc1OC(F)(F)F,,CC(C)=O,,O,O=S(=O)(O)O,test
US20140142085A1,COc1ccc2c(C)nn(CC(=O)N[C@@H](Cc3cc(F)cc(F)c3)c3ncccc3-c3cccc(C(N)=O)c3)c2c1>>Cc1nn(CC(=O)N[C@@H](Cc2cc(F)cc(F)c2)c2ncccc2-c2cccc(C(N)=O)c2)c2cc(O)ccc12,,ClCCl,,BrB(Br)Br,,test
US20130209400A1,CC(C)(C)OC(=O)N1CCC[C@@H](Nc2ccnc(-c3cnn4ccc(C#N)cc34)n2)C1>>N#Cc1ccn2ncc(-c3nccc(N[C@@H]4CCCNC4)n3)c2c1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20070161638A1,CC(C)S(=O)(=O)N[C@H]1Cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C1.FC(F)(F)c1ccc(Br)cn1>>CC(C)S(=O)(=O)N[C@H]1Cc2ccc(-c3ccc(C(F)(F)F)nc3)cc2C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20060205794A1,O=S(=O)(c1cccc(CCCCOCCCCCCNCC(O)c2ccc3c(n2)COC(c2ccccc2)O3)c1)C1CCCC1>>O=S(=O)(c1cccc(CCCCOCCCCCCNCC(O)c2ccc(O)c(CO)n2)c1)C1CCCC1,,CC(=O)O,O,,,test
US20110166161A1,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](O)CC1.COc1nc(O)ccc1C#N>>COc1nc(O[C@@H]2CC[C@@H](NC(=O)OC(C)(C)C)CC2)ccc1C#N,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100035869A1,CC(C)C[C@@H](/C=C/CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)NC(=O)OCc1ccccc1>>CC(C)C[C@@H](/C=C/CCO)NC(=O)OCc1ccccc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130252882A1,CCOC(=O)c1cc(C2CC2)c2c(C)c(-c3ccc(NC(=O)OC(C)(C)C)c(F)c3)c(F)cn2c1=O>>Cc1c(-c2ccc(N)c(F)c2)c(F)cn2c(=O)c(C(=O)O)cc(C3CC3)c12,,C1CCOC1,,Cl,[Na+].[OH-],test
US20080312211A1,COC(=O)c1[nH]c(C)c(C#N)c1N.O=C=Nc1ccc(Br)cc1>>COC(=O)c1[nH]c(C)c(C#N)c1NC(=O)Nc1ccc(Br)cc1,,ClCCCl,,CCN(CC)CC,,test
US20020137740A1,CCCN(c1nc(-c2ccc(OC)cc2Cl)c(C)s1)c1cc(C(=O)O)ccc1OC.[Li]C>>CCCN(c1nc(-c2ccc(OC)cc2Cl)c(C)s1)c1cc(C(C)=O)ccc1OC,,CCOC(C)=O,CCOCC,,,test
US20140038957A1,CNC1CCN(c2ncnc3[nH]ccc23)CC1.O=C(O)c1ccccc1>>CN(C(=O)c1ccccc1)C1CCN(c2ncnc3[nH]ccc23)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20010034343A1,Br.CCOC(=O)N1CCCN(c2nc3ccccc3[nH]2)CC1>>Br.c1ccc2[nH]c(N3CCCNCC3)nc2c1,,CCO,,,,test
US20090169483A1,COc1cc(C=O)cc(O)c1OC.ClCCOCCOCCCl>>COc1cc(C=O)cc(OCCOCCOCCCl)c1OC,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05101048,CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@H](Oc2ccccc2C(C)=O)SC[C@H]1OC(C)=O>>CC(=O)c1ccccc1O[C@@H]1SC[C@@H](O)[C@H](O)[C@H]1O,,CO,,C[O-].[Na+],,test
US20160024044A1,COc1ncccc1C=O.N#CCc1ccc(Cl)c(Cl)c1>>COc1ncccc1C(O)C(C#N)c1ccc(Cl)c(Cl)c1,,C1CCOC1,CCOCC,CC(=O)O,[Li]CCCC,test
US05977105,OC(CCl)CCc1cccnc1.Oc1ccccc1-c1ccccc1>>OC(CCc1cccnc1)COc1ccccc1-c1ccccc1,,CCO,,[Na+].[OH-],,test
US20040053942A1,CCCC[Sn](CCCC)(CCCC)c1ccncc1.Fc1ccc(-c2nn3ccccc3c2Br)cc1>>Fc1ccc(-c2nn3ccccc3c2-c2ccncc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOCC,Cc1ccccc1,[F-].[K+],,test
US06900209B2,Cc1cc(-c2nnc3c4ccccc4c(OCc4nnn(C)c4CO[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)nn23)no1>>Cc1cc(-c2nnc3c4ccccc4c(OCc4nnn(C)c4CO)nn23)no1,,C1CCOC1,CO,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20140155419A1,CCOC(=O)CBr.Cc1ccc(C(NC(=O)Cc2ccc(C(O)Cc3cccnc3C)cc2)c2ccccc2)c(C)c1>>CCOC(=O)COC(Cc1cccnc1C)c1ccc(CC(=O)NC(c2ccccc2)c2ccc(C)cc2C)cc1,,CC#N,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05521170,Cc1ccc(-c2ccccc2C(=O)Nc2ccc(C(=O)N3CCC(=O)N(CC(=O)N4CCN(C(=O)OC(C)(C)C)CC4)c4ccccc43)cc2)cc1>>Cc1ccc(-c2ccccc2C(=O)Nc2ccc(C(=O)N3CCC(=O)N(CC(=O)N4CCNCC4)c4ccccc43)cc2)cc1,,CCOC(C)=O,,Cl,,test
US20140018344A1,Cc1nc(S(C)(=O)=O)nc(N[C@@H](C)c2nc3ccn(C)c3cc2N2CCOCC2)c1C#N.N>>Cc1nc(N)nc(N[C@@H](C)c2nc3ccn(C)c3cc2N2CCOCC2)c1C#N,,C1COCCO1,,,,test
US20130280305A1,CCCCC/C=C\C/C=C\CCCCCCCCO[C@@H]1CN(CCCO)C[C@H]1OCCCCCCCC/C=C\C/C=C\CCCCC.CS(=O)(=O)O>>CCCCC/C=C\C/C=C\CCCCCCCCO[C@@H]1CN(CCCOS(C)(=O)=O)C[C@H]1OCCCCCCCC/C=C\C/C=C\CCCCC,,ClCCl,,CCN(CC)CC,,test
US20150291563A1,CS(=O)(=O)Cl.NC1CCN(c2cccc(C3CC(C(F)(F)C(F)(F)F)=NN3c3ccc(F)cc3F)c2)CC1>>CS(=O)(=O)NC1CCN(c2cccc(C3CC(C(F)(F)C(F)(F)F)=NN3c3ccc(F)cc3F)c2)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20150038488A1,CC(=O)OC(C)=O.COc1cc(-c2cc(O[C@H](C)[C@H]3CNC(=O)C3)c3scnc3c2)ccc1N1CCNCC1>>COc1cc(-c2cc(O[C@H](C)[C@H]3CNC(=O)C3)c3scnc3c2)ccc1N1CCN(C(C)=O)CC1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20090136473A1,COc1ccc(Cc2ccc(F)nc2)c(F)c1-c1cccc(Cl)c1.O=C(O)[C@@H]1CCCN1>>COc1ccc(Cc2ccc(N3CC[C@H]3C(=O)O)nc2)c(F)c1-c1cccc(Cl)c1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20080188528A1,COC(=O)c1ccc[nH]c1=O.FC(F)(F)c1cccc(C(Br)c2cccc(C(F)(F)F)c2)c1>>COC(=O)c1cccn(C(c2cccc(C(F)(F)F)c2)c2cccc(C(F)(F)F)c2)c1=O,,CN(C)C=O,,Cl,[H-].[Na+],test
US04803280,CCOC(=O)C(S)C(=S)Cc1ccc(Cl)cc1.COC(=O)NN>>COC(=O)NNC(=S)Cc1ccc(Cl)cc1,,ClCCl,,,,test
US20140343055A1,CC(C)c1nnc2ccc(F)cn12.N[C@H]1CC[C@@H](O)c2ccc(F)cc21>>CC(C)c1nnc2ccc(O[C@@H]3CC[C@H](N)c4cc(F)ccc43)cn12,,CN(C)C=O,,[H-].[Na+],,test
US20110306589A1,COCc1ccc(NC(=O)OC(C)(C)C)c(C(=O)OC)n1>>COCc1ccc(N)c(C(=O)OC)n1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],test
US20120077781A1,Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CC=O)c2cc1C.NCCCNS(=O)(=O)C(F)(F)F>>Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCNCCCNS(=O)(=O)C(F)(F)F)c2cc1C,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20150197527A1,CCCCCn1c2ccccc2c2nc(SCC(=O)OC(C)(C)C)n(-c3ccccc3)c(=O)c21>>CCCCCn1c2ccccc2c2nc(SCC(=O)O)n(-c3ccccc3)c(=O)c21,,CC#N,,O=C(O)C(F)(F)F,,test
US05616579,NC/C=C\COc1cc(CN2CCCCC2)ccn1.O=C(O)c1cccs1>>O=C(NC/C=C\COc1cc(CN2CCCCC2)ccn1)c1cccs1,,CCOC(C)=O,CN(C)C=O,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20110105508A1,Cc1cc(SCc2cc3cccc(C)c3nc2-c2ccccc2)nc(Cl)n1.N>>Cc1cc(SCc2cc3cccc(C)c3nc2-c2ccccc2)nc(N)n1,,C1CCOC1,CO,,,test
US20030004360A1,CC(C)(C)OC(=O)N[C@@H](Cc1cc(F)cc(F)c1)C(=O)CCl>>CC(C)(C)OC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CCl,,CCO,,C1CCOC1,[BH4-].[Na+],test
US04416890,NS(=O)(=O)c1nc2ccc(O)cc2s1.O=C(Cl)Cc1ccc(Cl)cc1>>NS(=O)(=O)c1nc2ccc(OC(=O)Cc3ccc(Cl)cc3)cc2s1,CN(C)c1ccncc1,CN(C)C=O,,CCN(CC)CC,Cl,test
US20120046278A1,Cc1cccc(N=C=O)c1.Nc1nc(N2CCNCC2)c2nc(CCc3ccc(F)cc3)sc2n1>>Cc1cccc(NC(=O)N2CCN(c3nc(N)nc4sc(CCc5ccc(F)cc5)nc34)CC2)c1,,ClCCl,,,,test
US05212310,Nc1nc(=O)[nH]c2cccnc12.O=C(CBr)c1ccccc1>>O=c1[nH]c2cccnc2c2nc(-c3ccccc3)cn12,,CN(C)C=O,,,,test
US20090036444A1,C#CC(=O)OC.N=C(NO)c1ccc(OCc2ccccc2)cc1F>>COC(=O)C=CONC(=N)c1ccc(OCc2ccccc2)cc1F,,CO,,CCOC(C)=O,,test
US20090137595A1,Nc1ccc(Oc2ccc3nccn3n2)cc1.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)Nc1ccc(Oc2ccc3nccn3n2)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20070099990A1,Cc1cc(C)c2c(c1C)OC(=O)C2c1ccccc1>>Cc1cc(C)c(C(CO)c2ccccc2)c(O)c1C,,CCCCCC,CCOC(C)=O,,,test
US20060205790A1,C[Si](C)(C)CCOCOc1ccc([C@@H](O)CNCCc2ccc3c(c2)O[C@H](COCc2ccccc2)CO3)cc1NC=O>>O=CNc1cc([C@@H](O)CNCCc2ccc3c(c2)O[C@H](COCc2ccccc2)CO3)ccc1O,,O,,,,test
US20110130371A1,CS(=O)(=O)Cl.C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2[C@H](O)C[C@]2(C)C(=O)[C@H]3C[C@H]3[C@@H]12>>C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2[C@H](OS(C)(=O)=O)C[C@]2(C)C(=O)[C@H]3C[C@H]3[C@@H]12,,CCOC(C)=O,c1ccncc1,,,test
US20140171435A1,CCS(=O)(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)c(OC)c1.N#Cc1ccc(Cl)cc1Br>>CCS(=O)(=O)c1ccc(-c2cc(Cl)ccc2C#N)c(OC)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20070027071A1,COC(=O)[C@@H]1C[C@@H](OC(=O)N2CCc3cccc(O)c3C2)CN1C(=O)OC(C)(C)C.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)[C@@H]1C[C@@H](OC(=O)N2CCc3cccc(OS(=O)(=O)C(F)(F)F)c3C2)CN1C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20130131018A1,C1CCC2=NCCCN2CC1.C[Si](C)(C)C#N>>N#Cc1nccc2ccccc12,,C1CCOC1,,,,test
US20080293694A1,CC(C)(C)OC(=O)N1CCc2c[nH]c3cccc(c23)C1.O>>CC(C)(C)OC(=O)N1CC(=O)c2c[nH]c3cccc(c23)C1,,C1CCOC1,O,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20040034015A1,CCOC(=O)N1CC[C@H]2[C@@H](C1)c1cccc3c1N2CC(=O)N3.CI.CN(C)C=O>>CCOC(=O)N1CCc2c(c3cccc4c3n2C(C)C(=O)N4C)C1,,O,,[H-].[Na+],,test
US20080300242A1,C=CS(C)(=O)=O.CCOc1cc(N2CCNCC2)ccc1[N+](=O)[O-]>>CCOc1cc(N2CCN(CCS(C)(=O)=O)CC2)ccc1[N+](=O)[O-],,C1COCCO1,,,,test
US20100029621A1,CC(C)(C)OC(=O)N1CCCN(Cc2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)CC1>>OC(c1ccc(CN2CCCNCC2)cc1)(C(F)(F)F)C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US04547506,Brc1ccc(Br)nc1.NCCCN>>NCCCNc1ccc(Br)cn1,,O,,Cl,c1ccncc1,test
US20070010573A1,CC1CCOS1(=O)=O.Sc1nc2ccccc2[nH]1>>CC(CCSc1nc2ccccc2[nH]1)S(=O)(=O)O,,C1COCCO1,O,,,test
US06355659B1,CS(=O)(=O)O.Clc1ccc(C2=CCN(CCCCn3cncn3)CC2)cc1>>CS(=O)(=O)O.Clc1ccc(C2=CCN(CCCCn3cncn3)CC2)cc1,,CC(C)=O,,,,test
US20160016951A1,C1CNC1.O=C(O)c1ccc2cncc(Br)c2n1>>O=C(c1ccc2cncc(Br)c2n1)N1CCC1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150266890A1,CC1(NS(=O)(=O)c2cccc(C(=O)O)c2)COC1.Nc1ccc(F)c(Br)c1>>CC1(NS(=O)(=O)c2cccc(C(=O)Nc3ccc(F)c(Br)c3)c2)COC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04732979,CCC(=O)OC(=O)CC.Clc1ccc2c(c1)CCC1=C2CCCN1>>CCC(=O)N1CCCC2=C1CCc1cc(Cl)ccc12,,c1ccncc1,,,,test
US04423070,CC(C)(N)CNC(=O)Cc1ccccc1.O=C(CBr)c1ccc(OCc2ccccc2)c(OCc2ccccc2)c1>>Br.CC(C)(CNC(=O)Cc1ccccc1)NCC(=O)c1ccc(OCc2ccccc2)c(OCc2ccccc2)c1,,C1COCCO1,CCOCC,,,test
US20100256146A1,COCCCN1C(=O)COc2ccc(CO[C@H]3CN(C(=O)OC(C)(C)C)CC[C@]3(O)c3ccc(COCCOC)cc3)cc21>>COCCCN1CCOc2ccc(CO[C@H]3CN(C(=O)OC(C)(C)C)CC[C@]3(O)c3ccc(COCCOC)cc3)cc21,,C1CCOC1,,B,CO,test
US07754735B2,CN1CCCC1=O.Cc1ccc2[nH]c(C)cc2c1.O=C([O-])O.O=[N+]([O-])c1cccc2c(Cl)ccnc12>>Cc1ccc2c(c1)c(-c1ccnc3c([N+](=O)[O-])cccc13)c(C)n2CC(=O)O,C1COCCO1,,,Cl,,test
US20060281789A1,COC(OC)c1ccc(OCCN2CCOCC2)c([N+](=O)[O-])c1>>COC(OC)c1ccc(OCCN2CCOCC2)c(N)c1,O=[Pt],CCO,,,,test
US04018790,CC(C)(C)O.O=C(Cl)c1ccc([N+](=O)[O-])c([N+](=O)[O-])c1>>CC(C)(C)OC(=O)c1ccc([N+](=O)[O-])c([N+](=O)[O-])c1,,c1ccncc1,,c1ccccc1,,test
US20120065214A1,COC(=O)c1cc(F)c(C)c(-n2cc(Br)nc(Br)c2=O)c1.C[C@@H](CO)[C@@H](N)c1ccccc1>>COC(=O)c1cc(F)c(C)c(-n2cc(Br)nc(N[C@@H](c3ccccc3)[C@@H](C)CO)c2=O)c1,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20100105679A1,Cc1cc(-n2ccc(OCc3ccccc3)cc2=O)ccc1[N+](=O)[O-]>>Cc1cc(-n2ccc(OCc3ccccc3)cc2=O)ccc1N,[Fe],CCO,O,[Cl-].[NH4+],,test
US20030232889A1,COC(=O)c1ccc(Nc2c(C(=O)O)ccc(F)c2F)c(F)c1.NOCCO>>COC(=O)c1ccc(Nc2c(C(=O)NOCCO)ccc(F)c2F)c(F)c1,,CO,,COc1nc(OC)nc([N+]2(C)CCOCC2)n1.[Cl-],,test
US04268509,CCON=C(C(=O)O)c1nsc(NC=O)n1>>CCON=C(C(=O)O)c1nsc(N)n1,,CCOC(C)=O,,Cl,[Na+].[OH-],test
US20160185779A1,O=C(Nc1cccc(Cl)c1)Oc1ccccc1.c1cc(-c2n[nH]c3c2CNCC3)sn1>>O=C(Nc1cccc(Cl)c1)N1CCc2[nH]nc(-c3ccns3)c2C1,,ClCCl,,,,test
US20070185175A1,CC(C)OB1OC(C)(C)C(C)(C)O1.Cn1cc(Br)c(-c2ccccc2F)n1>>Cn1cc(B2OC(C)(C)C(C)(C)O2)c(-c2ccccc2F)n1,,C1CCOC1,CCOC(C)=O,[Li]CCCC,[Cl-].[NH4+],test
US04291171,C=C(C(=O)OC)C(=O)OC.CC([N+](=O)[O-])[N+](=O)[O-]>>COC(=O)C(CC(C)([N+](=O)[O-])[N+](=O)[O-])C(=O)OC,,CCOCC,,CCN(CC)CC,,test
US04992441,CC(C)c1ccccc1N.ClCCNCCCl>>CC(C)c1ccccc1N1CCNCC1,,CCCCO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US05206418,COC(=O)c1ccc(N)cc1.O=C(O)Cc1ccc2c(c1)CCC(NS(=O)(=O)c1cccs1)C2>>COC(=O)c1ccc(NC(=O)Cc2ccc3c(c2)CCC(NS(=O)(=O)c2cccs2)C3)cc1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=S(Cl)Cl,test
US20070219230A1,CC(=O)c1cc2c(C)c(C)n(Cc3cccc(F)c3)c2c(N2CCc3ccccc3C2)n1.Cl>>Cc1c(C)n(Cc2cccc(F)c2)c2c(N3CCc4ccccc4C3)nc(C(C)O)cc12.Cl,,CO,,O,[BH4-].[Na+],test
US20090318431A1,O=Cc1c(F)ccc(F)c1F>>OCc1c(F)ccc(F)c1F,,CO,,[BH4-].[Na+],,test
US20020165274A1,CC(=O)Oc1c(C(C)(C)C)cc(C=O)cc1C(C)(C)C.CC(C)(C)NO>>CC(=O)Oc1c(C(C)(C)C)cc(C=[N+]([O-])C(C)(C)C)cc1C(C)(C)C,,CCOC(C)=O,,c1ccccc1,,test
US20150218150A1,Nc1cncc(-c2ccc(-c3ccc4c(c3)C(=O)NC4)s2)c1.O=S(=O)(Cl)c1ccc(F)cc1F>>O=C1NCc2ccc(-c3ccc(-c4cncc(NS(=O)(=O)c5ccc(F)cc5F)c4)s3)cc21,,CO,ClCCl,,,test
US20160046564A1,Cc1cc([N+](=O)[O-])c(C)cc1OC(C)C1CC1>>Cc1cc(OC(C)C2CC2)c(C)cc1N,[Fe],O,,CC(=O)O,,test
US04474602,CC(Cl)(CC(Cl)(Cl)Cl)c1ccc(Cl)nc1>>C=C(CC(Cl)(Cl)Cl)c1ccc(Cl)nc1,,Clc1ccccc1,,,,test
US04727192,CC1Cc2cc([N+](=O)[O-])cc([N+](=O)[O-])c2O1.CN>>CNc1c(CC(C)O)cc([N+](=O)[O-])cc1[N+](=O)[O-],,CCO,,,,test
US20140371204A1,CCOC(=O)Cn1ccc(C)n1.CN(C)C=O>>CCOC(=O)Cn1cc(CN(C)C)c(C)n1,,CC#N,ClCCl,,,test
US04330546,Brc1nccs1.CN(C)CCC(O)c1ccccc1>>CN(C)CCC(Oc1nccs1)c1ccccc1,,CS(C)=O,,[H-].[Na+],,test
US20150119385A1,COc1ccc(CNc2cc3c(cn2)ncn3C(C)C)cc1>>CC(C)n1cnc2cnc(N)cc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US06114330,C=CC(=O)Cl.C[Si](C)(C)OC1=CCCCC1.c1ccc2cnncc2c1>>C=CC(=O)N1N=Cc2ccccc2C1C1CCCCC1=O,,ClCCl,,,,test
US20100173774A1,C#CCBr.CCc1cc(C)cc(CC)c1C1C(=O)CC2(CCOCC2)CC1=O>>C#CCOC1=C(c2c(CC)cc(C)cc2CC)C(=O)CC2(CCOCC2)C1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20060241142A1,CN1CCC(CN)(c2ccc(F)cc2)CC1.Cc1c(C#N)cc(C(=O)Cl)c2ccccc12>>Cc1c(C#N)cc(C(=O)NCC2(c3ccc(F)cc3)CCN(C)CC2)c2ccccc12,,CCOCC,,,,test
US20110053921A1,CC(CCl)OC[C@@H](NC(=O)OCc1ccccc1)C(=O)O>>CC(CCl)OC[C@@H](N)C(=O)O,[Pd],CO,,,,test
US20160039838A1,Nc1ccc2c(cnn2Cc2cccc(F)c2)c1.O=[N+]([O-])c1cc2c(Cl)ncnc2cc1F>>O=[N+]([O-])c1cc2c(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)ncnc2cc1F,,CC(C)O,,,,test
US20040132727A1,CC(O)c1cccc(C(F)(F)F)c1.COc1cc2nccc(Oc3cc(C)c(N)cc3C)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3cc(C)c(NC(=O)OC(C)c4cccc(C(F)(F)F)c4)cc3C)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20130158019A1,NCc1ccc(OC(F)(F)F)cc1.O=C(O)[C@H]1CCCN(c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)C1>>O=C(NCc1ccc(OC(F)(F)F)cc1)[C@H]1CCCN(c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)C1,,ClCCl,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US06903107B1,CC(C)(C)OC(=O)N(CCC(=O)[O-])C1CCC1>>CC(C)(C)OC(=O)N(CCCO)C1CCC1,,CCCCCCC,CCOC(C)=O,,,test
US20100204196A1,Cc1ccc(S(=O)(=O)n2ccc3c(Cl)nc(Cl)nc32)cc1.Nc1cccc(Br)c1C(=O)O>>Cc1ccc(S(=O)(=O)n2ccc3c(Nc4cccc(Br)c4C(=O)O)nc(Cl)nc32)cc1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20080269244A1,Cc1nc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1[N+](=O)[O-]>>Cc1nc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1N,[Pd],C1CCOC1,,CO,[H][H],test
US05589478,Clc1cc(Cl)ncn1.OCCO>>OCCOc1cc(Cl)ncn1,,C1CCOC1,,[H-].[Na+],,test
US20040157838A1,Cc1cnc2c(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nn2c1O.O=P(Cl)(Cl)Cl>>Cc1cnc2c(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nn2c1Cl,,CCOC(C)=O,Cc1ccccc1,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20080269214A1,C#Cc1ccc(NC(=O)c2[nH]c(C)c(Cl)c2Cl)cc1.CCOC(=O)CN=[N+]=[N-]>>CCOC(=O)Cn1cc(-c2ccc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)cc2)nn1,[Cu]I,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20100004308A1,CC(=O)OC(C)=O.COc1cccc(CO)c1>>COc1cccc(COC(C)=O)c1,,CCOC(C)=O,,CCN(CC)CC,ClCCl,test
US20100286125A1,BrCCC1OCCO1.Cc1cc(C=O)ccc1F>>Cc1cc(C(O)CCC2OCCO2)ccc1F,,C1CCOC1,,II,,test
US20110237564A1,CCOC(=O)c1cnn(CC)c1C(=O)O.Nc1ccn2cc(-c3ccccc3)nc2n1>>CCOC(=O)c1cnn(CC)c1C(=O)Nc1ccn2cc(-c3ccccc3)nc2n1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20160016880A1,C[Si](C)(C)C=[N+]=[N-].O=C(O)CCC12CCC(OC(=O)c3cc(F)cc(F)c3)(CC1)C2>>[N-]=[N+]=CC(=O)CCC12CCC(OC(=O)c3cc(F)cc(F)c3)(CC1)C2,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20100048562A1,CC(C)OC(=O)c1cncn1C1CCCc2ccc([N+](=O)[O-])cc21.CCO>>CC(=O)Nc1ccc2c(c1)C(n1cncc1C(=O)OC(C)C)CCC2,[Pd],,,,,test
US20090280230A1,COS(=O)(=O)OC.Cc1ccc(C(N)=O)c(O)c1>>COc1cc(C)ccc1C(N)=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070129416A1,CCOc1cc(OC)ccc1C(=O)O.O=S(=O)(O)Cl>>CCOc1cc(OC)c(S(=O)(=O)Cl)cc1C(=O)O,,ClCCl,,,,test
US20120214767A1,COc1cc2c(cc1C)C(=O)CCC2.NO>>COc1cc2c(cc1C)/C(=N/O)CCC2,,CO,,Cl,CC(=O)[O-].[Na+],test
US05049544,C=C(C)C.CC(C(=O)O)C1CCCCC1>>CC(C(=O)OC(C)(C)C)C1CCCCC1,,CCOCC,,O=S(=O)(O)O,,test
US20110082181A1,CC(C)(CC=O)Cc1ccccc1.CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4Br)cc3)cc2)CC1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4C(O)CC(C)(C)Cc4ccccc4)cc3)cc2)CC1,,C1CCOC1,,[Li]CCCC,,test
US20100298324A1,COC(=O)c1cc(N=C=S)c(C(=O)OC)c(OC)c1.COc1ccc(N)nc1OC>>COc1ccc(-n2c(=S)[nH]c3cc(C(=O)O)cc(OC)c3c2=O)nc1OC,,C1CCOC1,,[Na+].[OH-],,test
US20050070712A1,N#CCc1ccc([N+](=O)[O-])cc1.O=C(Cl)COCc1ccccc1>>N#CC(C(=O)COCc1ccccc1)c1ccc([N+](=O)[O-])cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US05739116,C=CCOc1cccc(C(=O)O)c1.O=[O+][O-]>>O=CCOc1cccc(C(=O)O)c1,,ClCCl,,,,test
US20020128232A1,Nc1ccccc1NC(=S)Nc1cccc(C(F)(F)F)c1.O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O>>O=c1[nH]c2ccccc2n1C(=S)Nc1cccc(C(F)(F)F)c1,,CC#N,,,,test
US20020077336A1,N#Cc1cccc(-c2ccc3cc[nH]c(=O)c3c2)c1.O=C1CCC(=O)N1Cl>>N#Cc1cccc(-c2ccc3c(Cl)c[nH]c(=O)c3c2)c1,,CC(=O)N(C)C,,,,test
US20110212937A1,CCN.FC(F)(F)Oc1ccc(C2CCc3c(Cl)nc(Cl)nc32)cc1>>CCNc1nc(Cl)nc2c1CCC2c1ccc(OC(F)(F)F)cc1,,CO,,,,test
US20030100576A1,Cc1onc2c1c(=O)n(C1CCCC(CNC(=O)OCc3ccccc3)C1)c1cccc(Cl)c21>>CC(=O)c1c(N)c2c(Cl)cccc2n(C2CCCC(CNC(=O)OCc3ccccc3)C2)c1=O,,CC#N,O,,,test
US20110009454A1,CC(C)(C)OC(=O)NCc1cccc(Oc2cccc(C#C[Si](C)(C)C)c2)c1>>C#Cc1cccc(Oc2cccc(CNC(=O)OC(C)(C)C)c2)c1,,COC(C)(C)C,,CO,O=C([O-])[O-].[K+].[K+],test
US20060173014A1,CCN1CCCC(N)C1.O=S(=O)(Cl)c1ccc(Br)cc1>>CCN1CCCC(NS(=O)(=O)c2ccc(Br)cc2)C1,,ClCCl,,,,test
US20110152285A1,O=Cc1cc(I)c[nH]1.OCCBr>>O=Cc1cc(I)cn1CCO,,C1COCCO1,,CC(=O)O,[K+].[OH-],test
US20020055526A1,CN1CCCC1=O.NCc1ccccc1.O=[N+]([O-])c1nsnc1Cl>>Nc1c(NCc2ccccc2)ccc2nsnc12,[Pd],CCO,,CCN(CC)CC,,test
US20080026317A1,C=C(C)C(=O)Cl.CCCCC(C)(C)O>>C=C(C)C(=O)OC(C)(C)CCCC,,C1CCOC1,,[Li]CCCC,,test
US04332808,ClCc1ccccc1.Clc1cccc2[nH]ccc12>>Clc1cccc2c1ccn2Cc1ccccc1,,c1ccccc1,,[Na+].[OH-],,test
US20160237089A1,BrCCCOC1CCCCO1.Cn1c(=O)[nH]c(=O)c2c1nc(Oc1cccc(OC(F)(F)F)c1)n2COCC[Si](C)(C)C>>Cn1c(=O)n(CCCOC2CCCCO2)c(=O)c2c1nc(Oc1cccc(OC(F)(F)F)c1)n2COCC[Si](C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060217448A1,C/C(N)=C/C#N.O=C1CCN(Cc2ccccc2)CC1>>C/C(N)=C(\C#N)C1=CCN(Cc2ccccc2)CC1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,CCN(CC)CC,,test
US20140315886A1,CNc1nc(-c2cccnc2)nc2c(OC)cc(Br)cc12.COc1cccc(B(O)O)c1>>CNc1nc(-c2cccnc2)nc2c(OC)cc(-c3cccc(OC)c3)cc12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20050154048A1,CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)O.NNC(=O)c1ccc(N(Cc2ccccc2)Cc2ccccc2)s1>>CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NNC(=O)c1ccc(N(Cc2ccccc2)Cc2ccccc2)s1,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20150080365A1,CCOP(=O)(CS(=O)(=O)N1CCN(c2cc(C)ccn2)CC1)OCC.COC(O)C(F)(F)C(F)(F)F>>Cc1ccnc(N2CCN(S(=O)(=O)/C=C/C(F)(F)C(F)(F)F)CC2)c1,,C1CCOC1,,[H-].[Na+],,test
US06403628B1,CC(=O)c1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1S(C)=O.FC(F)(F)SCl>>CC(=O)c1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(NSC(F)(F)F)c1S(C)=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20050222138A1,CI.COc1ccc(Br)c(C(=O)O)c1>>COC(=O)c1cc(OC)ccc1Br,,CN(C)C=O,O,O=C([O-])O.[K+],,test
US20060171920A1,Nc1ccc2c(c1)C(CO)c1ccccc1-2.O=C(CCN1C(=O)C=CC1=O)OC(=O)CCN1C(=O)C=CC1=O>>O=C(CCN1C(=O)C=CC1=O)Nc1ccc2c(c1)C(CO)c1ccccc1-2,,O,,CN(C)C=O,O=C([O-])O.[Na+],test
US05648514,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CC=C3OS(=O)(=O)C(F)(F)F)cc1.CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2nccs2)=CCC3(C)C)cc1>>CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CC=C3c2nccs2)cc1,,C1CCOC1,,,,test
US20070149533A1,CC(C)(C)OC(=O)Nc1cc(Oc2ccc3ccc(C(=O)O)cc3c2)ccn1.Nc1ccc(Cl)c(C(F)(F)F)c1>>CC(C)(C)OC(=O)Nc1cc(Oc2ccc3ccc(C(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)cc3c2)ccn1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US05229395,CC(C)N=C=O.COc1ccc2nc3ccc(OC)cc3c(Nc3cccc(CO)c3)c2c1>>COc1ccc2nc3ccc(OC)cc3c(Nc3cccc(COC(=O)NC(C)C)c3)c2c1,,ClCCl,,CCN(CC)CC,,test
US20030069271A1,BrCC1CCC1.CCc1c(O)c2cc(F)ccc2[nH]c1=O>>CCc1c(OCC2CCC2)c2cc(F)ccc2[nH]c1=O,,CN(C)C=O,,[H-].[Na+],,test
US07071175B1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(CBr)cn1.CCOC(=O)CC(=O)OCC>>CCOC(=O)C(Cc1cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nc1)C(=O)OCC,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20110028469A1,COC(=O)c1sccc1N.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>COC(=O)c1sccc1NS(=O)(=O)c1ccc(C(F)(F)F)cc1,,ClCCl,,c1ccncc1,,test
US20160002188A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Fc1cccc2c(Br)n[nH]c12>>CC(C)(C)OC(=O)n1nc(Br)c2cccc(F)c21,CN(C)c1ccncc1,O,,ClCCl,,test
US20070254913A1,CCc1n[nH]c2cc(-c3ccnn3-c3ccc(S(C)(=O)=O)cc3)ccc12.IC1CCOCC1>>C1CCOCC1.c1ccc2[nH]ncc2c1,,CN(C)C=O,,[H-].[Na+],,test
US20100160388A1,COc1cc(N)c(F)cc1C.O=C(Cl)Cl>>COc1cc(N=C=O)c(F)cc1C,CN(C)c1ccncc1,Cc1ccccc1,,c1ccncc1,,test
US20140194404A1,CS/C(=C\C#N)N1CCN(C(=O)OC(C)(C)C)CC1.NN>>CC(C)(C)OC(=O)N1CCN(c2cc(N)[nH]n2)CC1,,CCO,,O,,test
US20090227579A1,NCCO.O=CCOCc1ccccc1>>OCCNCCOCc1ccccc1,,CCO,,[BH4-].[Na+],,test
US20100130506A1,O=C(NCC1(NC(=O)C(F)(F)F)CCN(Cc2ccncc2)CC1)C(F)(F)F>>NCC1(N)CCN(Cc2ccncc2)CC1,,CO,,N,,test
US20040209865A1,Brc1ccc(Br)nc1.C#Cc1ccc(OCCN2CCCC2)cc1>>Brc1ccc(C#Cc2ccc(OCCN3CCCC3)cc2)nc1,Cl[Cu],C1CCOC1,,CC(C)NC(C)C,,test
US05166188,COC(=O)C/C=C/c1ccc(N)cc1.CSC(=C[N+](=O)[O-])SC>>COC(=O)C/C=C/c1ccc(NC(=C[N+](=O)[O-])SC)cc1,,CCCO,,,,test
US20090197866A1,CCN(CC)C(=O)Nc1cn(C2CCCCO2)nc1-c1nc2cc(F)c(N3CCN(C)CC3)cc2[nH]1>>CCN(CC)C(=O)Nc1c[nH]nc1-c1nc2cc(F)c(N3CCN(C)CC3)cc2[nH]1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100105667A1,CCOC(=O)c1ccc(-c2c(F)c(OC)cc(OC)c2F)c2nccnc12.O=[N+]([O-])c1nc(CN2CCOCC2)c[nH]1>>COc1cc(OC)c(F)c(-c2ccc(C(=O)Nc3nc(CN4CCOCC4)c[nH]3)c3nccnc23)c1F,[Ni],CO,ClCCl,C1CCOC1,,test
US20090069180A1,CC1CCCN1c1nc(C#N)nc(Cl)c1/C(Br)=C(\Br)[Si](C)(C)C.O=C1CCC(=O)N1Cl>>CC1CCCN1c1nc(C#N)nc(Cl)c1/C(Br)=C(/Cl)Br,,ClCCCl,,[F-].[K+],,test
US20090170790A1,O=C1c2ccccc2C(=O)N1CCCOc1cccc(Br)c1.OB(O)c1cccnc1>>O=C1c2ccccc2C(=O)N1CCCOc1cccc(-c2cccnc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US05736487,CC(C)(Oc1ccc([N+](=O)[O-])cc1)c1nc2ccccc2s1>>CC(C)(Oc1ccc(N)cc1)c1nc2ccccc2s1,[Pd],CO,,,,test
US20120283264A1,CC(C(=O)O)(c1cncc(Br)c1)C(O[Si](C)(C)C(C)(C)C)c1cc(F)ccc1F.Cc1ccccc1.OCc1ccccc1.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>CC(=O)[O-].CC(NC(=O)OCc1ccccc1)(c1cncc(Br)c1)C(O[Si](C)(C)C(C)(C)C)c1cc(F)ccc1F.[NH4+],,Cc1ccccc1,,CCN(CC)CC,,test
US20130323435A1,CC(C)NC(C)C.[SiH3][SiH2]Cl>>CC(C)N([SiH2][SiH3])C(C)C,,CCCCCC,,,,test
US20090035215A1,Brc1ccc(CCOC2CCCCO2)cc1.CC(C)(C)[SiH](Cl)C(C)(C)C>>CC(C)(C)[SiH](c1ccc(CCOC2CCCCO2)cc1)C(C)(C)C,,C1CCOC1,,[Li]CCCC,O=C([O-])O.[Na+],test
US04675186,CCS.O=C(CBr)C12CC3CC(CC(C3)C1)C2>>CCSCC(=O)C12CC3CC(CC(C3)C1)C2,,C1CCOC1,,[Li]CCCC,,test
US20100160164A1,COC(=O)CC1C(C)=NN(c2ccc(Cl)nn2)C1(O)c1ccccc1>>COC(=O)Cc1c(C)nn(-c2ccc(Cl)nn2)c1-c1ccccc1,,CO,,[Na+].[OH-],,test
US20080227941A1,C=CCC(CC=C)CO[SiH2]c1ccc(Br)cc1.COc1ccc(B(O)O)cc1>>C=CCC(CC=C)CO[SiH2]c1ccc(-c2ccc(OC)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20090247507A1,CC(c1ccccc1)N1CCN(c2c(Br)cnc(N)c2[N+](=O)[O-])CC1.CN1CCN(c2ccc(C=O)cc2)CC1>>CC(c1ccccc1)N1CCN(c2c(Br)cnc3[nH]c(-c4ccc(N5CCN(C)CC5)cc4)nc23)CC1,,CCO,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20100152168A1,CC(C)(C)OC(=O)C(Br)c1ccccc1.CC(C)(C)OC(=O)n1c(=O)[nH]c2cc(I)ccc21>>CC(C)(C)OC(=O)C(c1ccccc1)n1c(=O)n(C(=O)OC(C)(C)C)c2ccc(I)cc21,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],[Cl-].[NH4+],test
US04547506,BrCc1ccccc1.NCCCNc1ccc(Br)cn1>>NCCCN(Cc1ccccc1)c1ccc(Br)cn1,,CS(C)=O,O,[H][H],[H-].[Na+],test
US20110224262A1,BrBr.Cc1[nH]ncc1-c1ccccc1>>Cc1[nH]nc(Br)c1-c1ccccc1,,CC(=O)O,,,,test
US20050032786A1,O=C(OO)c1cccc(Cl)c1.O=c1nc(-c2ccncc2)sc2ccccc12>>O=c1c2ccccc2sc(-c2ccncc2)[n+]1[O-],,ClC(Cl)Cl,,,,test
US20050272811A1,Nc1ccc2c(c1)OC(F)(F)O2.S=C(Cl)Cl>>FC1(F)Oc2ccc(N=C=S)cc2O1,,O,,Cl,ClCCl,test
US20090124596A1,CS(=O)(=O)Cl.O=C(N[C@H]1CC[C@@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccc(CCCO)cc4)c3)c2=O)CC1)c1cn2cc(F)ccc2n1>>CS(=O)(=O)OCCCc1ccc(-c2cccc(-n3c(=O)n([C@@H]4CC[C@H](NC(=O)c5cn6cc(F)ccc6n5)CC4)c(=O)c4cc(F)cnc43)c2)cc1,,ClCCl,,CCN(CC)CC,O,test
US20090192156A1,CN(C)C(=O)COC1CCNCC1.O=C(O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F>>CN(C)C(=O)COC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccccc34)ccc2F)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05861417,I.NC(=O)C1(c2cccnc2)CCNCC1>>I.NC(=O)C1(c2cccnc2)CCNCC1,,O,,CO,,test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCCC1CCN(C)CC1.Oc1ccc2[nH]ccc2c1F>>COc1cc2c(Oc3ccc4[nH]ccc4c3F)ncnc2cc1OCCC1CCN(C)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120115893A1,c1ccc2cnccc2c1>>c1cc2c(cn1)CCCC2,[Pd],O=C(O)C(F)(F)F,,,,test
US04207341,CCOC(=O)Cc1ccc(CCN)cc1.O=C(Cl)c1ccc(Cl)cc1>>CCOC(=O)Cc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1,,c1ccncc1,,,,test
US20070155727A1,CCN(C(C)C)C(C)C.CN(C)C=O.O=C(CBr)Nc1ccc(OCc2ccccc2)cc1>>O=C(CN1CC[C@@H](CN2CCCC2)C1)Nc1ccc(OCc2ccccc2)cc1,,CN(C)C=O,,,,test
US04898926,CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)OC(C)(C)C)C(C)C)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1>>CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)OC(C)(C)C)C(C)C)C(=O)N1CCC[C@H]1C(=O)O,[Pd],CC(=O)O,,,,test
US20110201593A1,NC1CCc2nc[nH]c2C1.O=[N+]([O-])c1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1Cl>>O=[N+]([O-])c1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1NC1CCc2nc[nH]c2C1,,CCO,,CCN(C(C)C)C(C)C,,test
US20130289125A1,CCCCC(O)C(=O)O.NCCc1ccc(O)cc1>>CCCCC(O)C(=O)NCCc1ccc(O)cc1,,CN(C)C=O,,On1nnc2ccccc21,,test
US20140378686A1,CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(F)cc(Br)c3C[C@H]2O)C1.N#C[Cu]>>CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(F)cc(C#N)c3C[C@H]2O)C1,,CS(C)=O,,,,test
US20090215758A1,COc1cc(C2=NC(=O)CS2)ccc1O.Cc1ccc(C=O)cc1>>COc1cc(C2=NC(=O)C(=Cc3ccc(C)cc3)S2)ccc1O,,O,,CC(=O)O,CC(=O)[O-].[Na+],test
US20110028493A1,COC(=O)c1ccc(CC(N)=S)cc1.O=C(CBr)c1cccc(C(F)(F)F)c1>>COC(=O)c1ccc(Cc2nc(-c3cccc(C(F)(F)F)c3)cs2)cc1,,CCO,,,,test
US20130131035A1,Clc1ccc(OC2CNC2)c(Cl)c1.Clc1ccnc(Cl)n1>>Clc1ccc(OC2CN(c3ccnc(Cl)n3)C2)c(Cl)c1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US06162808,CCOC(=O)c1csc(Cn2cc(C3c4ccccc4C=Cc4ccccc43)c(=S)[nH]c2=O)n1>>O=C(O)c1csc(Cn2cc(C3c4ccccc4C=Cc4ccccc43)c(=S)[nH]c2=O)n1,,CO,O,[Li+].[OH-],,test
US20070213371A1,CC(C)(C)[Si](C)(C)OCc1cc(C(F)(F)F)ccc1C(O)C1CCCCC1.CI>>COC(c1ccc(C(F)(F)F)cc1CO[Si](C)(C)C(C)(C)C)C1CCCCC1,,C1CCOC1,,O,[H-].[Na+],test
US20100029650A1,CC(C)c1noc(N2CCC([C@@H](C)O)CC2)n1.CS(=O)(=O)Cl>>CC(C)c1noc(N2CCC([C@@H](C)OS(C)(=O)=O)CC2)n1,,ClCCl,,CCN(CC)CC,,test
US20060148858A1,CC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCO.COC(=O)Cc1cccc(OC)c1O>>COc1cccc(CC(=O)O)c1OCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1C(C)C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20060122399A1,CCOC(OCC)C(=N)OC.CNN=C(N)C(F)F>>CCOC(OCC)c1nc(C(F)F)nn1C,,CO,,Cl,CC(=O)[O-].[Na+],test
US05221671,CCC#Cc1cccc(OC(=O)[O-])c1.OC1CCNCC1>>C#CCCOC(=O)N1CCC(O)CC1,,CCOC(C)=O,,CCCCCC,,test
US20130143877A1,CCc1cc2c(cc1N1CCN(C3CCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O.CS(=O)(=O)O>>CCc1cc2c(cc1N1CCN(C3CCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O.CS(=O)(=O)O,,CC#N,,CN(C)C=O,,test
US20100292207A1,CN1CCC[C@H]1COc1ccc(C(=O)OC(C)(C)C)c(NC2CCOCC2)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CN1CCC[C@H]1COc1ccc(C(=O)OC(C)(C)C)c(N(C(=O)C(F)(F)F)C2CCOCC2)c1,,ClCCl,,,,test
US20020137689A1,CNCCS(=O)(=O)O.O=C1C(CCC(O)c2ccc(F)cc2)C(c2ccc(OCCCCI)cc2)N1c1ccc(F)cc1>>CN(CCCCOc1ccc(C2C(CCC(O)c3ccc(F)cc3)C(=O)N2c2ccc(F)cc2)cc1)CCS(=O)(=O)O,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20060135578A1,CCc1nc(/C=C/c2cn(-c3ccccc3)nc2OCc2ccc(OCc3nc(-c4cccc([N+](=O)[O-])c4)oc3C)c(OC)c2)cs1>>CCc1nc(/C=C/c2cn(-c3ccccc3)nc2OCc2ccc(OCc3nc(-c4cccc(N)c4)oc3C)c(OC)c2)cs1,[Fe],CCO,,[Ca+2].[Cl-].[Cl-],,test
US20030225059A1,C[Si](C)(C)CCOCCl.OCC(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[Si](C)(C)CCOCOCC(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20160009718A1,C#CC(=O)OCC.O=C(CBr)C1CCN(C(=O)OCc2ccccc2)CC1.c1ccnnc1>>CCOC(=O)c1cc(C(=O)C2CCN(C(=O)OCc3ccccc3)CC2)n2ncccc12,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150225422A1,Cc1ncc(Br)cc1O.OCC1CC1>>Cc1ncc(Br)cc1OCC1CC1,,C1CCOC1,O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060100201A1,CCOC(=O)C#N.C[Si](C)(C)CCOCn1cc(C#N)nc1Br>>CCOC(=O)c1nc(C#N)cn1COCC[Si](C)(C)C,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20100087502A1,Cc1nn(-c2ccc(OCc3ccccc3)c(F)c2)c2cccc(OCc3ccccc3)c12>>Cc1nn(-c2ccc(O)c(F)c2)c2cccc(O)c12,[Pd],CCOC(C)=O,,,,test
US06613942B1,COc1cc(O)ccc1C=O.O=C(CBr)N[C@H]1CCN(Cc2ccccc2)C1>>COc1cc(OCC(=O)N[C@H]2CCN(Cc3ccccc3)C2)ccc1C=O,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US04339588,BrCc1ccccc1.Oc1cnoc1>>c1ccc(COc2cnoc2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160159814A1,C[C@H](O)c1cccc2c1C(F)(F)C(=O)N2Cc1ccncc1F.O=C(OO)c1cccc(Cl)c1>>C[C@H](O)c1cccc2c1C(F)(F)C(=O)N2Cc1cc[n+]([O-])cc1F,,ClC(Cl)Cl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20150025056A1,CC(C)(C)OC(=O)[C@H]1CC(CC(=O)NCCCCCNC(=O)OCc2ccccc2)CN[C@@H]1C(=O)N1CCC(c2ccccc2)C1>>O=C(CC1CN[C@H](C(=O)N2CCC(c3ccccc3)C2)[C@@H](C(=O)O)C1)NCCCCCNC(=O)OCc1ccccc1,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20100093718A1,COC(OC)N(C)C.NC(=S)Nc1cccc(Br)c1>>CN(C)/C=N/C(=S)Nc1cccc(Br)c1,,CCOCC,,,,test
US20090142297A1,COc1ccc(C(=O)Cl)cc1.NCc1ccc2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2=O>>COc1ccc(C(=O)NCc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)cc1,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US06462036B1,OCCN1CCOCC1.Oc1ccc(-c2n[nH]c3c2Cc2ccccc2-3)cc1>>c1ccc2c(c1)Cc1c(-c3ccc(OCCN4CCOCC4)cc3)n[nH]c1-2,,ClCCl,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05753679,O=C(O)c1ccc(NC(=O)C(F)(F)F)nc1.OC1CCN(Cc2ccccc2)CC1>>Nc1ccc(C(=O)OC2CCN(Cc3ccccc3)CC2)cn1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20130096150A1,COC(=O)C1Cc2cc3c(cc2CN1C(=O)OC(C)(C)C)O[C@@H](c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1)CN3>>CC(C)(C)OC(=O)N1Cc2cc3c(cc2CC1C(=O)O)NC[C@H](c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1)O3,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20060211709A1,COC(=O)c1nccnc1N.N>>NC(=O)c1nccnc1N,,CO,,,,test
US20050209277A1,N[C@H]1CCCc2cccnc21>>N[C@H]1CCCc2cccnc21,,O,,Cl,[Na+].[OH-],test
US20160185780A1,CC(C)(C)OC(=O)CBr.OCC1(c2ccc(Cl)cc2)CCN(c2cccn3nc(Nc4cn[nH]c4)nc23)CC1>>CC(C)(C)OC(=O)Cn1cc(Nc2nc3c(N4CCC(CO)(c5ccc(Cl)cc5)CC4)cccn3n2)cn1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US06218376B1,Cc1nc2c(o1)C=Cc1cc(O[Si](C)(C)C(C)(C)C)ccc1C2c1cn(-c2ccnc(Cl)n2)c(=O)[nH]c1=O.O=C(O)C1CNC1>>Cc1nc2c(o1)C=Cc1cc(O)ccc1C2c1cn(-c2ccnc(N3CC(C(=O)O)C3)n2)c(=O)[nH]c1=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20130281657A1,CC(C)(C)OC(=O)NCCCNC(=S)NC(=O)c1ccccc1>>CC(C)(C)OC(=O)NCCCNC(N)=S,,CO,,[Na+].[OH-],,test
US20120264734A1,CCN(c1cc(-c2ccc(CN3CCOCC3)cc2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCSCC1.O=C(OO)c1cccc(Cl)c1>>CCN(c1cc(-c2ccc(CN3CCOCC3)cc2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCS(=O)CC1,,ClCCl,,,,test
US05910506,CC(C#N)c1nc(CO[Si](C)(C)C(C)(C)C)n(C)c1Sc1cccc(Cl)c1>>CC(C#N)c1nc(CO)n(C)c1Sc1cccc(Cl)c1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05049564,COC1c2ccccc2C2CN(Cc3ccccc3)CC21.Cl>>COC1c2ccccc2C2CNCC21.Cl,[Pd],CO,,,,test
US20090186898A1,CCOC(=O)c1cc(Cl)nn2ccnc12.NN>>NNC(=O)c1cc(Cl)nn2ccnc12,,CCO,,O,,test
US20090182142A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Clc1ccc(CNc2cc(Cl)nc3ccnn23)c(Cl)c1>>CC(C)(C)OC(=O)N(Cc1ccc(Cl)cc1Cl)c1cc(Cl)nc2ccnn12,CN(C)c1ccncc1,ClC(Cl)Cl,,,,test
US20050239636A1,C1CCOC1.O.O=C(Cl)c1ccccc1.OCC1(CO)c2ccccc2-c2ccccc21.c1ccncc1>>O=C(OCC1(COC(=O)c2ccccc2)c2ccccc2-c2ccccc21)c1ccccc1,,O,,,,test
US20150344480A1,Cn1nc(-c2ccc(F)cc2)cc1-c1ccncc1.O=C1CCC(=O)N1Br>>Cn1nc(-c2ccc(F)cc2)c(Br)c1-c1ccncc1,,CCOC(C)=O,ClCCl,,,test
US20120190548A1,C=C(F)[Sn](CCCC)(CCCC)CCCC.COC(=O)c1nc(Cl)c(F)c(N)c1I>>C=C(F)c1c(C(=O)OC)nc(Cl)c(F)c1N,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC(Cl)Cl,,,,test
US06821980B1,CCOc1cc(Cc2cnc(N)nc2N)cc(O)c1-c1ccc(CN2CCOCC2)c(F)c1.CN(C)S(=O)(=O)Cl>>CCOc1cc(Cc2cnc(N)nc2N)cc(OS(=O)(=O)N(C)C)c1-c1ccc(CN2CCOCC2)c(F)c1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20040209933A1,FC1(F)Oc2ccc(C=Cc3nc(CCl)co3)cc2O1.Oc1ccc(CCCCn2ccnn2)cc1>>FC1(F)Oc2ccc(C=Cc3nc(COc4ccc(CCCCn5ccnn5)cc4)co3)cc2O1,,O,,CN(C)C=O,[H-].[Na+],test
US04431834,CCCOC(=O)C(C)Oc1ccc(O)cc1.CS(=O)(=O)OC1Cc2ccccc2C1>>CCCOC(=O)C(C)Oc1ccc(OC2Cc3ccccc3C2)cc1,,CCC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20060004046A1,CCOc1c(C#N)cnc2ccc(C=O)cc12.O=C1CSC(N[C@@H]2C[C@H]2c2ccccc2)=N1>>CCOc1c(C#N)cnc2ccc(/C=C3\SC(N[C@@H]4C[C@H]4c4ccccc4)=NC3=O)cc12,,Cc1ccccc1,,C1CCNCC1,,test
US06172228B2,Clc1cccc(NCc2ccccc2)c1.O=C(O)C(O)C(O)C(=O)O>>Clc1cccc(NCc2ccccc2)c1.O=C(O)C(O)C(O)C(=O)O,,O,,,,test
US20120115881A1,CCCC#N.Nc1ccc(Cl)cc1>>CCCC(=N)Nc1ccc(Cl)cc1,,Cc1ccccc1,O,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20040220234A1,CC[Mg]Br.CN(CCC=O)C(=O)OC(C)(C)C>>CCC(O)CCN(C)C(=O)OC(C)(C)C,,C1CCOC1,,[Cl-].[NH4+],,test
US20090259049A1,Br.CCCCN(c1c(OC)nn2c(-c3c(OC)cc(COCC)cc3OC)csc12)C1CCOCC1>>Br.CCCCN(c1c(OC)nn2c(-c3c(OC)cc(COCC)cc3OC)csc12)C1CCOCC1,,O,,CC(C)=O,,test
US20110263571A1,Cc1cc(F)ncc1C(=O)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1.O=C1NCCO1>>Cc1cc(N2CCOC2=O)ncc1C(=O)N1CCN(c2ncc(C3CC3)cc2C2CC2)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US20120322785A1,CS(=O)(=O)Cl.C[C@H](O)CCO.O=C(Cl)c1ccccc1>>C[C@@H](CCOC(=O)c1ccccc1)OS(C)(=O)=O,,ClCCl,ClCCl,CCN(CC)CC,c1ccncc1,test
US20030073640A1,CCCCCCCC/C=C\CCCCCCCCN.CCCCCCCCCCCCCCCCBr>>CCCCCCCCCCCCCCCCCCCCCCCC/C=C\CCCCCCCCN,,ClC(Cl)Cl,,[Na+].[OH-],,test
US20100267707A1,CN(C)CCNC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1>>CN(C)CCNC(=O)N1CCN(c2ccc(N)cc2)CC1,[Pt],CO,,,,test
US20060009431A1,O=C1CCC(=O)O1.O=[N+]([O-])OC[C@@H](CO)O[N+](=O)[O-]>>O=C(O)CCC(=O)OC[C@H](CO[N+](=O)[O-])O[N+](=O)[O-],CN(C)c1ccncc1,C1CCOC1,,,,test
US20150307493A1,CC(=O)c1cc2c(c(-c3cn(C)c(=O)c4[nH]ccc34)c1)OC(C(C)C)C(=O)N2>>CC(O)c1cc2c(c(-c3cn(C)c(=O)c4[nH]ccc34)c1)OC(C(C)C)C(=O)N2,,CO,,[BH4-].[Na+],,test
US20140228386A1,Nc1cccc(C(F)(F)F)c1.O=C=NCCCl>>O=C(NCCCl)Nc1cccc(C(F)(F)F)c1,,Cc1ccccc1,,,,test
US04654343,CCOC(=O)Nc1cccc(-c2ccc3nnc(C)n3n2)c1.CI>>CCOC(=O)N(C)c1cccc(-c2ccc3nnc(C)n3n2)c1,,O,,CN(C)C=O,[H-].[Na+],test
US20080194549A1,COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN(C(=O)N(C)c2ccccc2)C2CC2)C(C)C)ccc1OC>>COCCCOc1cc(C(=O)N(C[C@@H]2CNC[C@H]2CN(C(=O)N(C)c2ccccc2)C2CC2)C(C)C)ccc1OC,,C1COCCO1,Cl,,,test
US06620817B1,CN(C)C(=O)CNc1cc(-c2ccccc2)nc(-c2ccc(C(F)(F)F)cc2)n1.O=C1CCC(=O)N1Cl>>CN(C)C(=O)CNc1nc(-c2ccc(C(F)(F)F)cc2)nc(-c2ccccc2)c1Cl,,CC(=O)O,,,,test
US20060089355A1,CCOC(=O)c1ccccc1OCCCOC>>COCCCOc1ccccc1C(=O)O,,CCO,O,[Na+].[OH-],,test
US20120071460A1,CCOC(=O)CC(=O)c1ccncc1.CS(=O)(=O)c1cccc(C(N)=NO)c1>>CS(=O)(=O)c1cccc(-c2noc(CC(=O)c3ccncc3)n2)c1,,Cc1ccccc1,,,,test
US20010044436A1,CSc1nc(Cl)c2c(n1)CCN(C(=O)OC(C)(C)C)C2.Oc1ccc(Cl)cc1Cl>>CSc1nc2c(c(Oc3ccc(Cl)cc3Cl)n1)CN(C(=O)OC(C)(C)C)CC2,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20050209291A1,Nc1ccc2nc(NC3CCN(Cc4ccccc4)CC3)sc2c1.O=C(N=C=S)c1ccccc1>>O=C(NC(=S)Nc1ccc2nc(NC3CCN(Cc4ccccc4)CC3)sc2c1)c1ccccc1,,C1CCOC1,,,,test
US20130237518A1,Cn1nc(-c2ccc3[nH]nc(Br)c3c2)nc1[C@@H]1CCCN(C(=O)OC(C)(C)C)C1.OB(O)c1ccncc1>>Cn1nc(-c2ccc3[nH]nc(-c4ccncc4)c3c2)nc1[C@@H]1CCCN(C(=O)OC(C)(C)C)C1,,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150099777A1,CCc1nc(O)c(C(=O)OC)cc1C(=O)OC.O=P(Cl)(Cl)Cl>>CCc1nc(Cl)c(C(=O)OC)cc1C(=O)OC,,CC#N,,O=C([O-])O.[Na+],,test
US04436753,COC1=C(OC)C(=O)C(CCCCCCCCCCCOC(C)=O)=C(C)C1=O>>COC1=C(OC)C(=O)C(CCCCCCCCCCCO)=C(C)C1=O,,CO,,Cl,O=C([O-])O.[Na+],test
US20080103129A1,O=C(CS(=O)(=O)c1ccc(F)cc1)N(CCCCBr)OC(c1ccccc1)(c1ccccc1)c1ccccc1>>O=C1C(S(=O)(=O)c2ccc(F)cc2)CCCCN1OC(c1ccccc1)(c1ccccc1)c1ccccc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04680300,Cc1ccc(S(=O)(=O)OCCCCCCCl)cc1.Oc1ccccc1-c1ccccc1>>ClCCCCCCOc1ccccc1-c1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080188520A1,CCCI.O=S1(=O)CCCN1[C@@H](c1ccccc1)[C@H](O)c1ccccc1>>CCCO[C@H](c1ccccc1)[C@H](c1ccccc1)N1CCCS1(=O)=O,,CS(C)=O,O,[Na+].[OH-],,test
US20090029905A1,Cc1csc(N)n1.O=C(O)c1cc(Oc2cnc(C(=O)N3CCC3)cn2)cc(O[C@H]2CCOC2)c1>>Cc1csc(NC(=O)c2cc(Oc3cnc(C(=O)N4CCC4)cn3)cc(O[C@H]3CCOC3)c2)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160168090A1,C=O.O=C(NCC1CCC(F)(F)CC1)c1cn(C[C@@H]2CCN2)c2cccc(Cl)c12>>CN1CC[C@H]1Cn1cc(C(=O)NCC2CCC(F)(F)CC2)c2c(Cl)cccc21,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090118333A1,Nc1cncc(S(N)(=O)=O)c1.O=C(O)c1ccc(C(F)(F)F)cc1Oc1ccc(C(F)(F)F)nc1>>NS(=O)(=O)c1cncc(NC(=O)c2ccc(C(F)(F)F)cc2Oc2ccc(C(F)(F)F)nc2)c1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100317048A1,O=C1NC(=O)c2ccccc21.OCCCCCCCCCCCCCCCCCCCCBr>>O=C1c2ccccc2C(=O)N1CCCCCCCCCCCCCCCCCCCCBr,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040209892A1,CC=CCN.O=Cc1cc([N+](=O)[O-])ccc1Cl>>C=C(C)CNCc1cc([N+](=O)[O-])ccc1Cl,,CCO,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160115158A1,COc1cc(Cl)nnc1NS(=O)(=O)Cc1cc(C#N)ccc1Cl>>N#Cc1ccc(Cl)c(CS(=O)(=O)Nc2nnc(Cl)cc2O)c1,,ClCCl,,BrB(Br)Br,,test
US20110257179A1,COc1ccc(Cn2cc(C(=O)C(F)Br)cn2)cc1.Cc1cccc(NC(N)=S)n1>>COc1ccc(Cn2cc(-c3nc(Nc4cccc(C)n4)sc3F)cn2)cc1,,CC(C)=O,,,,test
US20060046986A1,CCOC(=O)N1CCNCC1.COc1c(NC(=O)c2cc3cccc(CN4CCN(C(=O)OC(C)(C)C)CC4)c3n2C)cc(C(C)(C)C)cc1NS(C)(=O)=O>>CCOC(=O)N1CCN(Cc2cccc3cc(C(=O)Nc4cc(C(C)(C)C)cc(NS(C)(=O)=O)c4OC)n(C)c23)CC1,,CC(Cl)Cl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20050282812A1,CC(C)(C)OC(=O)C[C@@H]1CC[C@@H](C(=O)O)CC1>>CC(C)(C)OC(=O)C[C@@H]1CC[C@@H](CO)CC1,,C1CCOC1,,,,test
US20110245353A1,Cc1cccc(N)c1C(=O)O.O=C(Cl)OC(Cl)(Cl)Cl>>Cc1cccc2[nH]c(=O)oc(=O)c12,,C1COCCO1,,CCOCC,,test
US20140094462A1,CCOCCN.C[C@H]1[C@@H](c2ccccc2)OC(=O)CCC=CC[C@@H](CC(=O)O)C(=O)N1C>>CCOCCNC(=O)C[C@@H]1CC=CCCC(=O)O[C@H](c2ccccc2)[C@H](C)N(C)C1=O,,CN(C)C=O,,CO,ClCCl,test
US20120028954A1,O=C(O)c1cccc(C(=O)N2CCN(Cc3ccc(F)cc3)CC2)n1.c1ccc(N2CCNCC2)cc1>>O=C(c1cccc(C(=O)N2CCN(c3ccccc3)CC2)n1)N1CCN(Cc2ccc(F)cc2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120094996A1,CN(C)CCN.COc1ccc(-c2nn3c(-c4cnc(S(C)=O)nc4)cnc3s2)cc1OC>>COc1ccc(-c2nn3c(-c4cnc(NCCN(C)C)nc4)cnc3s2)cc1OC,,C1COCCO1,,,,test
US20090209536A1,CC(C)(C)c1ccc(Nc2nc(-c3ccc(F)c(F)c3)nc3ccccc23)cc1.CI>>CN(c1ccc(C(C)(C)C)cc1)c1nc(-c2ccc(F)c(F)c2)nc2ccccc12,,C1CCOC1,,[H-].[Na+],,test
US20110112151A1,Nc1nnc(SCC(=O)C23CC4CC(CC(C4)C2)C3)s1.O=C(Cl)C1CC1>>O=C(Nc1nnc(SCC(=O)C23CC4CC(CC(C4)C2)C3)s1)C1CC1,,ClCCl,,,,test
US05932601,COc1cc(C=CC=C2OC(=O)NC2=O)ccc1OCc1coc(-c2ccccc2)n1>>COc1cc(CCCC2OC(=O)NC2=O)ccc1OCc1coc(-c2ccccc2)n1,O=[Pt],,,,,test
US20030228652A1,COCCOCCOCCO.OCCOCCOCCOCCO>>COCCOCCOCCOCCOCCOCCOCCO,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20070003539A1,Cl.N#Cc1cccc2[nH]ccc12>>Cl.NCc1cccc2c1CCN2,[Pd],CO,,C1COCCO1,,test
US05143912,COC(=O)c1cc(-c2ccccc2)c(=O)[nH]c1-c1c(F)cccc1C#N>>COC(=O)c1cc(-c2ccccc2)c(=O)n2c1-c1c(F)cccc1C2,[Zn],CC(=O)O,,,,test
US04868271,CN(C)C=O.ClCCCl.Nc1ccc(Oc2ccccc2)cc1.O=C(Cl)c1cccc(C(=O)Cl)c1.O=C(Cl)c1cccc(C(=O)Cl)n1>>O=C(Nc1ccc(Oc2ccccc2)cc1)c1cccc(C(=O)Nc2ccc(Oc3ccccc3)cc2)n1,,CN(C)C=O,ClCCCl,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20060111375A1,COc1cc2nccc(Cl)c2cc1OC.Oc1cc2ccncc2cc1-c1cccnc1>>COc1cc2nccc(Oc3cc4ccncc4cc3-c3cccnc3)c2cc1OC,CN(C)c1ccncc1,Clc1ccccc1Cl,,O,,test
US20140107073A1,COc1ncnc2ccc(-c3cccnc3-c3ccc(F)c(Cl)c3)nc12>>O=c1[nH]cnc2ccc(-c3cccnc3-c3ccc(F)c(Cl)c3)nc12,,CCO,,Cl,,test
US04937375,C=C(c1ccccc1)c1cccc(C(C)C(=O)O)c1.O=[Mn](=O)(=O)[O-]>>CC(C(=O)O)c1cccc(C(=O)c2ccccc2)c1,,c1ccccc1,,O,,test
US20120329649A1,C=Cc1ccc(-n2cncn2)cc1.CON(C)C(C)=O>>C=Cc1ccc(-n2ncnc2C(C)=O)cc1,,C1CCOC1,,[Li]CCCC,,test
US20120040951A1,CC(N=[N+]=[N-])c1cnc(Nc2ccc(C(F)(F)F)cc2)cn1>>CC(N)c1cnc(Nc2ccc(C(F)(F)F)cc2)cn1,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20130079346A1,COC(=O)c1cc(C(N)=S)ccc1-c1ccccc1[N+](=O)[O-].O=C(CBr)c1ccccc1>>O=C(O)c1cc(-c2nc(-c3ccccc3)cs2)ccc1-c1ccccc1[N+](=O)[O-],,O,,,,test
US20070072865A1,CC1(C)OC(=O)N2CCNCC21.O=C(Cl)Oc1ccccc1>>CC1(C)OC(=O)N2CCN(C(=O)Oc3ccccc3)CC21,,C1CCOC1,,CCN(CC)CC,O,test
US20030096838A1,CC(C)C(=O)Cl.NNc1ccc(-c2ocnc2-c2ccccc2)cn1>>CC(C)C(=O)NNc1ccc(-c2ocnc2-c2ccccc2)cn1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20030176454A1,CS(=O)(=O)O.N=C(Nc1cccc(Nc2noc3ccccc23)c1)c1ccccc1>>CS(=O)(=O)O.N=C(Nc1cccc(Nc2noc3ccccc23)c1)c1ccccc1,,CO,,CC(C)OC(C)C,,test
US20140296208A1,C#Cc1cc(Nc2cc(Oc3ccc(N)c4ccccc34)ccn2)cc(C(=O)NCCOCCOCCOC)c1.CC(C)(C)c1cc(NC(=O)Oc2ccccc2)cc(C(N)=O)c1>>C#Cc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(C(N)=O)cc(C(C)(C)C)c4)c4ccccc34)ccn2)cc(C(=O)NCCOCCOCCOC)c1,,CC(=O)OC(C)C,,CCN(CC)CC,,test
US20070213359A1,COc1cccc2c(C(=O)NCc3cccc(C)c3)c[nH]c12.ClCCCI>>COc1cccc2c(C(=O)NCc3cccc(C)c3)cn(CCCCl)c12,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150018546A1,CCOC(=O)c1c(O)c2c(C)ncnc2n(OCc2ccccc2)c1=O.NCc1ccccc1>>Cc1ncnc2c1c(O)c(C(=O)NCc1ccccc1)c(=O)n2OCc1ccccc1,,ClC(Cl)Cl,,Cl,,test
US20120165343A1,CC(C)C[C@H](N[S@@](=O)C(C)(C)C)c1cnc(-c2ccc(C(F)(F)F)cc2)nc1.Cl>>CC(C)C[C@H](N)c1cnc(-c2ccc(C(F)(F)F)cc2)nc1.Cl,,CO,,CCOCC,,test
US20100173910A1,COc1c(Nc2ccc(Cl)cc2)c(=O)c1=O.NCCNc1cc(N2CCCC2)nc(N2CCCC2)n1>>O=c1c(NCCNc2cc(N3CCCC3)nc(N3CCCC3)n2)c(Nc2ccc(Cl)cc2)c1=O,,CCO,,,,test
US06821980B1,CCOc1cc(Cc2cnc(N)nc2N)cc(OCC)c1-c1ccc(C)c([N+](=O)[O-])c1>>CCOc1cc(Cc2cnc(N)nc2N)cc(OCC)c1-c1ccc(C)c(N)c1,[Pd],CC(=O)O,,CCO,O,test
US20100240889A1,CCOC(=O)c1cc(-c2csc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)n2)on1>>O=C(O)c1cc(-c2csc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)n2)on1,,CCO,,Cl,[Na+].[OH-],test
US20090281308A1,CCOC(=O)C1CCNCC1.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOC(=O)C1CCN(S(=O)(=O)c2ccc(C)cc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20120225875A1,Nc1cnccc1Nc1cc(-c2cc(Cl)ccc2F)nc2ccccc12>>Nc1cnccc1Nc1cc(-c2ccccc2F)nc2ccccc12,[Pd],C1CCOC1,,CCN(CC)CC,,test
US20120238486A1,C=C(C#N)C1CC(C)(C)CC1C>>CC(C#N)C1CC(C)(C)CC1C,[Pd],Cc1ccccc1,,[H][H],,test
US20070185324A1,Cc1ccc(C(=O)O)c(N)c1I.NC=O>>Cc1ccc2c(=O)[nH]cnc2c1I,,CN1CCCC1=O,,,,test
US20040209901A1,C[C@H](N)CO.Cc1cc(F)ccc1-c1nc(S(C)(=O)=O)nc2c1ccc(=O)n2-c1ccccc1F>>Cc1cc(F)ccc1-c1nc(N[C@@H](C)CO)nc2c1ccc(=O)n2-c1ccccc1F,,C1CCOC1,,,,test
US04746747,COC(=O)c1cc(OC)c2c(c1)OCO2.COC(C)=O>>COC(=O)CC(=O)c1cc(OC)c2c(c1)OCO2,,CN(C)C=O,,CC(=O)O,[H-].[Na+],test
US04382087,CCCC(=O)CC(=O)OCC.N=C(N)C(Cl)(Cl)Cl>>CCCc1cc(O)nc(C(Cl)(Cl)Cl)n1,,O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080194670A1,Cc1sc(C(=O)C=Cc2ccc(C(=O)O)cc2)c2c1[C@H]1[C@@H](C2)C1(C)C>>Cc1sc(C(=O)CCc2ccc(C(=O)O)cc2)c2c1[C@H]1[C@@H](C2)C1(C)C,[Pd],C1CCOC1,CCO,,,test
US20070249670A1,CC(C)(C)N(C(=O)[O-])[C@H](c1nnn[nH]1)C1CCCCC1>>N[C@H](c1nnn[nH]1)C1CCCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120308588A1,CCOC(=O)[C@H](O)[C@H](N)Cc1ccccc1Cl.CCc1ccc(C(=O)O)cc1N.COC(=O)c1cc(C)sc1N=C=O>>CCc1ccc(C(=O)N[C@H](Cc2ccccc2Cl)[C@@H](O)C(=O)O)cc1-n1c(=O)[nH]c2sc(C)cc2c1=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120028952A1,CCc1nc(N)ccc1C#C[Si](C)(C)C>>C#Cc1ccc(N)nc1CC,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04956482,C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC[C@]2(OC=O)C(=O)CCl>>C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)CO)CC[C@@H]12,,CO,O,O=C([O-])O.[K+],,test
US20100113502A1,CC1CCN(C(=O)c2ccc3c(c2)c2c(n3C)CCN(C(=O)OC(C)(C)C)C2)CC1.Cl>>CC1CCN(C(=O)c2ccc3c(c2)c2c(n3C)CCNC2)CC1.Cl,,CCOCC,CO,,,test
US20120071478A1,CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)cn1.C[C@@H](Nc1cnc2cc(Br)ccc2n1)c1cccc(Cl)c1>>C[C@@H](Nc1cnc2cc(-c3cnn(C(=O)OC(C)(C)C)c3)ccc2n1)c1cccc(Cl)c1,,C1COCCO1,,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US20130116235A1,C[C@H]1CN(C2COC2)CCN1c1ccc(Nc2cc(-c3ccnc(-n4ncc5c6c(sc5c4=O)CCCC6)c3C=O)cn(C)c2=O)nc1>>C[C@H]1CN(C2COC2)CCN1c1ccc(Nc2cc(-c3ccnc(-n4ncc5c6c(sc5c4=O)CCCC6)c3CO)cn(C)c2=O)nc1,,CO,ClCCl,O,[BH4-].[Na+],test
US20100305096A1,CC(C)(C)OC(=O)N1CC(=O)C1.CC1(C)CNCCO1>>CC(C)(C)OC(=O)N1CC(N2CCOC(C)(C)C2)C1,,ClCCCl,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150232463A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc(C)c(-c2ccc(O)cc2)c1N1CCC(C)(C)CC1.N#Cc1ccc(CCO)cc1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc(C)c(-c2ccc(OCCc3ccc(C#N)cc3)cc2)c1N1CCC(C)(C)CC1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020132810A1,CC(=O)OC(CC(CCC(C)(C)O)c1ncc[nH]1)C(Cc1cccc(F)c1)NC(=O)c1cnc2ccccc2n1>>CC(C)(O)CCC(CC(O)C(Cc1cccc(F)c1)NC(=O)c1cnc2ccccc2n1)c1ncc[nH]1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20120108583A1,COC(=O)c1cc2nc(Nc3c(Cl)cncc3Cl)n(C)c2c2c1OC(C)(C)C2.Nc1ccc(C(F)(F)F)cc1>>Cn1c(Nc2c(Cl)cncc2Cl)nc2cc(C(=O)Nc3ccc(C(F)(F)F)cc3)c3c(c21)CC(C)(C)O3,,Cc1ccccc1,,C[Al](C)C,,test
US20100016396A1,COC(=O)C(Br)Cc1cc(Oc2c(C)c(C)nn2C)c(Cl)cc1Cl.NC(N)=S>>Cc1nn(C)c(Oc2cc(CC3SC(=N)NC3=O)c(Cl)cc2Cl)c1C,,CCO,,CC(=O)[O-].[Na+],,test
US20140350011A1,CN(C)c1ccc(C=O)cc1.NC(=O)[C@H]1[C@@H]2C=C[C@@H](C2)[C@H]1Nc1c(Br)cnc(N)c1N>>CN(C)c1ccc(-c2nc3c(N[C@@H]4[C@H]5C=C[C@H](C5)[C@@H]4C(N)=O)c(Br)cnc3[nH]2)cc1,,CCO,,C,O=C[O-].[NH4+],test
US04337343,CCCCc1nc2c(s1)CCCC2C(=O)OCC>>CCCCc1nc2c(s1)CCCC2CO,,CCOCC,,,,test
US20160039865A1,CS(=O)(=O)Cl.C[C@]12CC[C@H](N)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](c3ccc(=O)oc3)CC[C@]12O>>C[C@]12CC[C@H](NS(C)(=O)=O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](c3ccc(=O)oc3)CC[C@]12O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110190297A1,Cc1cncc(C)c1Cl.NC(=O)C1CCNCC1.O=C([O-])O>>Cc1cncc(C)c1C1CCC(C(N)=O)CC1,,O,,Cl,,test
US20110294812A1,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCc3ccnc(NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)c3)c3ccccc23)cc1>>CN[C@@H](C)C(=O)Nc1cc(COc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)c3ccccc23)ccn1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20070185155A1,C=CCCCCBr.OC(c1ccccc1)(c1ccccc1)C12CCN(CC1)CC2>>C=CCCCC[N+]12CCC(C(O)(c3ccccc3)c3ccccc3)(CC1)CC2.[Br-],,CC#N,,,,test
US20110124695A1,CCOC(=O)[C@@H](C)OS(=O)(=O)C(F)(F)F.N[C@@H](Cc1ccc(-c2cccc(Cl)c2)cc1)C(=O)OCc1ccccc1>>CCOC(=O)[C@H](C)N[C@@H](Cc1ccc(-c2cccc(Cl)c2)cc1)C(=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20090131492A1,CC(C)(C)c1cc2c(C#N)c([N+](=O)[O-])ccc2[nH]1.OCCI>>CC(C)(C)c1cc2c(C#N)c([N+](=O)[O-])ccc2n1CCO,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090036492A1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.Cc1c(C)c(C=O)c(C)c(C)c1O>>COc1cc(O)c2c(c1C(=O)NCc1c(C)c(C)c(O)c(C)c1C)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US05250546,CCCCCCC(N)C(O)c1ccccc1.Cl.ClCCCN1CCCCC1>>CCCCCCC(NCCCN1CCCCC1)C(O)c1ccccc1.Cl.Cl,,CCCCCC,CCO,CCOC(C)=O,,test
US20100056490A1,CN(C)C=Nc1c(F)cc(C[C@@H]2CS(=O)(=O)C[C@H]3[C@H]2OC(=O)N3Cc2cccc(C(C)(C)C)c2)cc1C[C@H](O)C(F)(F)F>>CC(C)(C)c1cccc(CN[C@H]2CS(=O)(=O)C[C@@H](Cc3cc(F)c(N)c(C[C@H](O)C(F)(F)F)c3)[C@@H]2O)c1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20060008673A1,Cc1ccc(Br)nc1.OB(O)c1ccc(Br)cc1>>Cc1ccc(-c2ccc(Br)cc2)nc1,,CCOC(C)=O,O,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20140315220A1,COc1ccc(C(SCCC(=O)ON2C(=O)CCC2=O)(c2ccc(OC)cc2)c2ccc(OC)c(C#CCCC(=O)NCc3ccccc3)c2)cc1.NCCCOCCOCCOCCCNC(=O)C1(F)C#CCCCCC1>>COc1ccc(C(SCCC(=O)NCCCOCCOCCOCCCNC(=O)C2(F)C#CCCCCC2)(c2ccc(OC)cc2)c2ccc(OC)c(C#CCCC(=O)NCc3ccccc3)c2)cc1,,ClCCl,,CCN(CC)CC,,test
US07612067B2,CC(=O)CCl.CCCC(CCC)c1cc(C)nnc1N>>CCCC(CCC)c1cc(C)nn2cc(C)nc12,,CCO,,O=C([O-])O.[Na+],,test
US20100121048A1,C[C@H](N)c1ccccc1.[C-]#[N+]C(C(=O)OC)=C(Br)c1ccccc1>>COC(=O)c1ncn([C@@H](C)c2ccccc2)c1-c1ccccc1,,CN(C)C=O,O,CCN(CC)CC,Cl,test
US20060148858A1,CCC(CC)c1nn(-c2ccc(Br)cn2)cc1CCCO.CCc1cccc(CC(=O)OC)c1O>>CCc1cccc(CC(=O)OC)c1OCCCc1cn(-c2ccc(Br)cn2)nc1C(CC)CC,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20110190278A1,COC(=O)c1ccc(O)cc1C(F)(F)F.O=[N+]([O-])O>>COC(=O)c1cc([N+](=O)[O-])c(O)cc1C(F)(F)F,,CC(=O)O,,O=S(=O)(O)O,,test
US05204344,COC(=O)C(C)(C)CC(=O)CSC(C)(C)C.COc1cccc(NN)c1>>COC(=O)C(C)(C)Cc1[nH]c2cc(OC)ccc2c1SC(C)(C)C,,CC(C)(C)O,,Cl,,test
US20160152613A1,CC1(C)OC(=O)CC(=O)O1.O=Cc1cc(Cl)ccc1C(F)(F)F>>CC1(C)OC(=O)C(=Cc2cc(Cl)ccc2C(F)(F)F)C(=O)O1,,Cc1ccccc1,O,C1CCNCC1,CC(=O)O,test
US20160229860A1,CC(C)(C)OC(=O)Nc1ncc(C#Cc2cnc3ccc(-c4ccc(C(=O)N5CCOCC5)cc4)nn23)s1>>Nc1ncc(C#Cc2cnc3ccc(-c4ccc(C(=O)N5CCOCC5)cc4)nn23)s1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20130172339A1,Cc1csc2ccc(Br)cc12.O=S(=O)(O)Cl>>Cc1c(S(=O)(=O)Cl)sc2ccc(Br)cc12,,ClC(Cl)Cl,,,,test
US20100029619A1,COC(=O)C1(c2ccc(C(=O)Nc3cn4cc(Cl)ccc4n3)cc2)CC1>>O=C(Nc1cn2cc(Cl)ccc2n1)c1ccc(C2(C(=O)O)CC2)cc1,,C1CCOC1,CCO,[K+].[OH-],,test
US04820834,CN1C(=O)C(N)N=C(c2ccccc2)c2ccccc21.O=C=Nc1ccc([N+](=O)[O-])cc1>>CN1C(=O)C(NC(=O)Nc2ccc([N+](=O)[O-])cc2)N=C(c2ccccc2)c2ccccc21,,C1CCOC1,,,,test
US20150232435A1,CC(C)(C)c1cc(N2CCN(CCCCN)CC2)nc(C(C)(C)C)n1.O=C(n1ccnc1)n1ccnc1.O=S(=O)(c1ccccc1)N1CCNCC1>>CC(C)(C)c1cc(N2CCN(CCCCNC(=O)N3CCN(S(=O)(=O)c4ccccc4)CC3)CC2)nc(C(C)(C)C)n1,,CO,ClC(Cl)Cl,,,test
US20130029938A1,CCCC[C@]1(CC)CS(=O)(=O)c2cc(OC)c(O)cc2[C@@H](c2ccccc2)N1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCCC[C@]1(CC)CS(=O)(=O)c2cc(OC)c(OS(=O)(=O)C(F)(F)F)cc2[C@@H](c2ccccc2)N1,,ClCCl,,c1ccncc1,,test
US20110142796A1,O=C(OCC1c2ccccc2-c2ccccc21)N1CCOC2(CCN(Cc3ccccc3)CC2)C1>>O=C(OCC1c2ccccc2-c2ccccc21)N1CCOC2(CCNCC2)C1,,CCO,,,,test
US20070173506A1,COc1ccc(CN(C(=O)OC(C)(C)C)c2nc(Cl)c(-c3ccc4cnccc4c3)s2)cc1>>Nc1nc(Cl)c(-c2ccc3cnccc3c2)s1,,CC(=O)O,,,,test
US20060005320A1,NCCc1cccs1.O=[N+]([O-])c1ccc(F)cc1>>O=[N+]([O-])c1ccc(NCCc2cccs2)cc1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20140243286A1,COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCN)c1nnc(C)n1-2.O=C(O)Cc1ccc(O)c(O)c1>>COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCNC(=O)Cc1ccc(O)c(O)c1)c1nnc(C)n1-2,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110183989A1,COC(=O)C1CN(C(=O)OC(C)(C)C)CCN1.O=C=N[C@@H]1C[C@H]1c1ccccc1>>CC(C)(C)OC(=O)N1CCN2C(=O)N([C@@H]3C[C@H]3c3ccccc3)C(=O)C2C1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20090221586A1,BrCC1CCC1.COc1ccc(-c2nc(CCC(=O)c3ccccn3)co2)cc1O>>COc1ccc(-c2nc(CCC(=O)c3ccccn3)co2)cc1OCC1CCC1,,CCO,,C1CCC2=NCCCN2CC1,O,test
US20070049616A1,CCN=C=O.N#Cc1ccc(C2CCc3cncn32)c(N)c1>>CCNC(=O)Nc1cc(C#N)ccc1C1CCc2cncn21,,CN(C)C=O,,,,test
US20120065183A1,CC(C)(C)OC(=O)N1CC[C@H](O)C1.Clc1ncnc2c1CN(Cc1ccccc1)CC2>>CC(C)(C)OC(=O)N1CC[C@H](Oc2ncnc3c2CN(Cc2ccccc2)CC3)C1,,C1CCOC1,,,,test
US20160068515A1,CC(=O)NCCBr.O=c1[nH]ncn1-c1ccc(Br)cc1F>>CC(=O)NCCn1ncn(-c2ccc(Br)cc2F)c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20090197864A1,C[C@@H](Oc1c(N)ncc2c(C3=CCNCC3)coc12)c1c(Cl)ccc(F)c1Cl.O=C(O)CO>>C[C@@H](Oc1c(N)ncc2c(C3=CCN(C(=O)CO)CC3)coc12)c1c(Cl)ccc(F)c1Cl,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US04962096,CC(=O)OC(C)=O.CCCCCCCCCCCCCCCCOC(C)C(O)COCc1ccccc1>>CCCCCCCCCCCCCCCCOC(C)C(COCc1ccccc1)OC(C)=O,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20120165347A1,CC(C)(C)S(=O)N=C1c2cc(Br)ccc2CC12CCOCC2>>N=C1c2cc(Br)ccc2CC12CCOCC2,,C1COCCO1,,CCOCC,Cl,test
US20110190258A1,Cc1ccc(Br)cc1C=O.OCCO>>Cc1ccc(Br)cc1C1OCCO1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US03992408,O=C1c2ccccc2C(=O)N1Cc1cnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2>>NCc1cnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2,,CCO,,NN,O,test
US20110319439A1,COc1cc(Br)ccc1OCC(C)(C)O.O=c1nc(SCc2ccc(Cl)cc2)cc[nH]1>>COc1cc(-n2ccc(SCc3ccc(Cl)cc3)nc2=O)ccc1OCC(C)(C)O,[Cu]I,C1COCCO1,ClCCl,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20160016961A1,CS(=O)(=O)Cl.Nc1cncc(-c2cc(NCc3ccccc3)c3c(Cl)ccn3n2)c1>>CS(=O)(=O)Nc1cncc(-c2cc(NCc3ccccc3)c3c(Cl)ccn3n2)c1,,C1CCOC1,,CCN(CC)CC,,test
US20070185140A1,N[C@H]1CC[C@H](N)CC1.O=C(CCl)c1ccc2c(c1)CCN2c1ncnc2[nH]cnc12>>CC(=O)c1ccc2c(c1)CCN2c1nc(N[C@@H]2CC[C@@H](N)CC2)nc2[nH]cnc12,,O,,,,test
US04612317,BrCc1ccccc1.OC[C@H]1Cc2c([nH]c3ccccc23)CN1.S=C=S>>OC[C@H]1Cc2c([nH]c3ccccc23)CN1C(=S)SCc1ccccc1,,CCO,,[K+].[OH-],,test
US20090203657A1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2cccc(-c3cccc(C=O)c3)c2)n1.C[C@H]1CNC[C@@H](C)N1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2cccc(-c3cccc(CN4C[C@H](C)N[C@H](C)C4)c3)c2)n1,,CS(C)=O,,CC(=O)O,,test
US20060211734A1,C[C@H]1C[C@@H](Oc2cccc(NC(=O)c3ccc(F)cc3Cl)n2)CCN1C(=O)OC(C)(C)C>>C[C@H]1C[C@@H](Oc2cccc(NC(=O)c3ccc(F)cc3Cl)n2)CCN1,,C1COCCO1,,Cl,,test
US20120040952A1,O=C(C1CNC1)N1CCCN(C2CCC2)CC1.O=C(Cl)CC1CCOCC1>>O=C(CC1CCOCC1)N1CC(C(=O)N2CCCN(C3CCC3)CC2)C1,,ClCCl,O,CCN(C(C)C)C(C)C,Cl,test
US20090099161A1,CC(C)Cn1cnc2c(N)nc3ccc(/C=C/CN4CCCC4=O)cc3c21>>CC(C)Cn1cnc2c(N)nc3ccc(CCCN4CCCC4=O)cc3c21,[Pd],CCO,,CO,,test
US20090221555A1,CNC(=O)c1ccccc1Nc1nc(Cl)ncc1Br.COc1cc2c(cc1N)CCN(CC(=O)N(C)C)CC2>>CNC(=O)c1ccccc1Nc1nc(Nc2cc3c(cc2OC)CCN(CC(=O)N(C)C)CC3)ncc1Br,,CC(C)O,,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US20100184815A1,CC(C)(C)OC(=O)C(C)(C)Oc1ccc(C(=O)OCc2cn(Cc3ccc(SC(F)(F)F)cc3)nn2)cc1>>CC(C)(Oc1ccc(C(=O)OCc2cn(Cc3ccc(SC(F)(F)F)cc3)nn2)cc1)C(=O)O,,C1COCCO1,,Cl,,test
US20060128702A1,CC(=O)c1ccccc1NC(=O)c1ccc(F)cc1>>O=c1cc(-c2ccc(F)cc2)[nH]c2ccccc12,,CC(C)(C)O,,CC(C)(C)[O-].[K+],,test
US20060100442A1,CC(=O)C#CC[C@H](C)COC1CCCCO1>>CC(=O)CCC[C@H](C)COC1CCCCO1,[Pd],C1CCOC1,,[H][H],,test
US05677470,COC(=O)[C@@H](OS(=O)(=O)c1ccc(C)cc1)[C@H](O)c1ccc(F)cc1>>COC(=O)[C@@H]1O[C@@H]1c1ccc(F)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040072853A1,N#CN.Nc1ccccc1.O=[N+]([O-])O>>NC(=[NH2+])Nc1ccccc1.O=[N+]([O-])[O-],,CCO,,,,test
US20160207887A1,CC(C)=CCO.O=C(Cl)c1ccccc1>>CC(C)=CCOC(=O)c1ccccc1,,c1ccncc1,,,,test
US20040242884A1,CNCC(O)c1cccc(NC(C)=O)c1.Cc1c(CCl)sc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12>>CC(=O)Nc1cccc(C(O)CN(C)Cc2sc3c(=O)c(C(=O)NCc4ccc(Cl)cc4)cn(C)c3c2C)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20110301370A1,BrC(Br)(Br)Br.COC(=O)C/C(C(=O)OC)=C(\CCCCO)C(=O)OC>>COC(=O)C/C(C(=O)OC)=C(\CCCCBr)C(=O)OC,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110183985A1,CC(=O)c1cc(Cl)c2cccnc2c1-c1ccccc1F>>CC(O)c1cc(Cl)c2cccnc2c1-c1ccccc1F,,CO,,[BH4-].[Na+],,test
US04290954,CC(=O)O.N#Cc1ccc2oc3c(c(=O)c2c1)CCCC3.O=S(=O)(O)O>>O=C(O)c1ccc2oc3c(c(=O)c2c1)CCCC3,,O,,,,test
US03992535,COC(=O)C1=C(O)c2ccc3ccccc3c2S(=O)(=O)N1C.COc1cccc(N)c1>>COc1cccc(NC(=O)C2=C(O)c3ccc4ccccc4c3S(=O)(=O)N2C)c1,,Cc1ccccc1C,,,,test
US03931326,C/C=C/C(=O)C1=C(C)C=CCC1(C)C>>CC1=CC(=O)C2C(C)(C)CC=CC12C,,C1COCCO1,,,,test
US20100137300A1,CCOC(=O)C=[N+]=[N-].Cc1cc2cc(C#N)ccn2c1>>CCOC(=O)Cc1c(C)cc2cc(C#N)ccn12,[Cu],Cc1ccccc1,,,,test
US20150126498A1,COc1cc(F)c(CN2C(=O)N(c3ccc(OC)c(OC)c3)S(=O)(=O)c3cccnc32)c(F)c1.NCc1c(F)cc(F)cc1F.O=C(n1ccnc1)n1ccnc1>>COc1cc(N2C(=O)N(Cc3c(F)cc(F)cc3F)c3ncccc3S2(=O)=O)cnc1OC,,CN(C)C=O,,CCN(CC)CC,,test
US20050059733A1,CC(=O)Cl.CCCc1c(O)cc(C=Cc2ccccc2)cc1O.CCN(CC)CC.ClCCl.O>>CCCc1c(OC(C)=O)cc(C=Cc2ccccc2)cc1OC(C)=O,,ClCCl,,,,test
US20100120860A1,CC(C)(C)OC(=O)NC1CCNCC1.Fc1ccc(CBr)cc1F>>NC1CCN(Cc2ccc(F)c(F)c2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20110046127A1,CCOC(=O)c1c(C)nc2ccc(Cl)nn12.Nc1ccccc1>>Cc1nc2ccc(Cl)nn2c1C(=O)Nc1ccccc1,,ClCCl,,C[Al](C)C,Cl,test
US04629795,CNC.Clc1ccc(CBr)cc1>>CN(C)Cc1ccc(Cl)cc1,,CN(C)C=O,,,,test
US20040110767A1,Cl.O=C(C1CCCCC1)N(Cc1ccc(OC2CCCCO2)cc1Cl)c1ccc(OCCN2CCCC2)cc1>>Cl.O=C(C1CCCCC1)N(Cc1ccc(O)cc1Cl)c1ccc(OCCN2CCCC2)cc1,,CCO,,O=C([O-])O.[Na+],,test
US20050203094A1,COCCOCOc1ccc(C(CC(=O)OC)C(=O)OC)cc1>>COCCOCOc1ccc(C(CO)CCO)cc1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050038081A1,CC(=O)Oc1cccc(C(=O)Nc2cc(C(=O)Nc3cc(F)cc(N4CCOCC4)c3)ccc2Cl)c1>>O=C(Nc1cc(F)cc(N2CCOCC2)c1)c1ccc(Cl)c(NC(=O)c2cccc(O)c2)c1,,CO,,C[O-].[Na+],,test
US20040053974A1,Cc1ccc(O[C@H](C(=O)N2C(=O)OC[C@@H]2Cc2ccccc2)[C@H](O)c2ccc(OCc3ccccc3)cc2)cc1>>Cc1ccc(O[C@H](C(=O)N2C(=O)OC[C@@H]2Cc2ccccc2)[C@H](O)c2ccc(O)cc2)cc1,[Pd],CCO,,[H][H],,test
US20090270374A1,C=CCI.O=c1n[n+]([O-])c2ccc(Cl)cc2[nH]1>>C=CCn1c(=O)n[n+]([O-])c2ccc(Cl)cc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04684739,NCC1COc2ccccc2O1.O=C(CCCl)Nc1ccc2c(c1)OCO2>>O=C(CCNCC1COc2ccccc2O1)Nc1ccc2c(c1)OCO2,,CN(C)C=O,,CCN(CC)CC,O,test
US20060100431A1,CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)F.O=C(c1ccccc1)N1C[C@H](O)[C@H]2NCC[C@H]21>>CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N1CC[C@@H]2[C@H]1[C@@H](O)CN2C(=O)c1ccccc1,,CN(C)C=O,,,,test
US20090176992A1,COc1ccccc1OCCN1C[C@@H](CO)OC1=S.O=S(Cl)Cl>>COc1ccccc1OCCN1C[C@@H](CCl)OC1=S,,ClCCl,,CCN(CC)CC,,test
US20090176794A1,COc1ccc2c(c1)CCN2.O=N[O-]>>COc1ccc2c(c1)CCN2N=O,,O,,CC(=O)O,,test
US20040167030A1,O=[N+]([O-])c1ccc(Cl)nc1CS(=O)(=O)c1ccccc1.c1ccc(CN2CCNCC2)cc1>>O=[N+]([O-])c1ccc(N2CCN(Cc3ccccc3)CC2)nc1CS(=O)(=O)c1ccccc1,,CCO,O,O=C([O-])[O-].[K+].[K+],,test
US20030207875A1,COc1nc(N)c(Cl)cc1C(=O)CCC1CCN(CC(C)C)CC1>>CC(C)CN1CCC(CCC(=O)c2cc(Cl)c(N)[nH]c2=O)CC1,,Cl,,,,test
US20140094462A1,C[C@@H]1[C@@H](c2ccccc2)OC(=O)CCC=CC[C@@H](CC(=O)O)C(=O)N1C.NCc1ccc(Cl)cc1>>C[C@@H]1[C@@H](c2ccccc2)OC(=O)CCC=CC[C@@H](CC(=O)NCc2ccc(Cl)cc2)C(=O)N1C,,ClCCl,,CO,,test
US20160229839A1,COC(=O)c1cccc(-c2c[nH]c(C3C(c4ccccc4)CCCN3C(=O)OC(C)(C)C)n2)c1>>COC(=O)c1cccc(-c2c[nH]c(C3NCCCC3c3ccccc3)n2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US07074801B1,NC1CC1.O=[N+]([O-])c1cccc(S(=O)(=O)Cl)c1>>Nc1cccc(S(=O)(=O)NC2CC2)c1,,O,,C1CCOC1,,test
US20100041663A1,Cc1c(Cc2ccccc2)nnc(N2CCNCC2)c1C.O=C(Cl)Oc1ccccc1>>Cc1c(Cc2ccccc2)nnc(N2CCN(C(=O)Oc3ccccc3)CC2)c1C,,ClCCl,,CN1CCOCC1,,test
US05571828,CC(=O)c1ccc(NCCCN2CCC(c3noc4cc(F)ccc34)CC2)c(O)c1.CI>>COc1cc(C(C)=O)ccc1NCCCN1CCC(c2noc3cc(F)ccc23)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US05166170,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccccc1C1Cc2ccccc2N1>>CC(C)(C)OC(=O)Nc1ccccc1C1Cc2ccccc2N1C(=O)OC(C)(C)C,,CCN(CC)CC,ClCCl,,,test
US20040186301A1,CCOC(=O)CCCCBr.SC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)CCCCSC(c1ccccc1)(c1ccccc1)c1ccccc1,,CCOCC,CN(C)C=O,[H-].[Na+],[Cl-].[NH4+],test
US06211227B1,COC(=O)c1sccc1CBr.Nc1cccc(S)c1>>COC(=O)c1sccc1CSc1cccc(N)c1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20160137652A1,COC(=O)CC1CCNCC1.Fc1ccc2nccc(Cl)c2c1>>COC(=O)CC1CCN(c2ccnc3ccc(F)cc23)CC1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US20040102432A1,CN(CCN1CCC(Oc2ccc(F)c(F)c2)CC1)C(=O)C(F)(F)F>>CNCCN1CCC(Oc2ccc(F)c(F)c2)CC1,,CCO,,[Na+].[OH-],,test
US20070244115A1,COc1ccc2nc(SCc3nccc(N4CCOCC4)c3Cl)[nH]c2n1.O=C(OO)c1cccc(Cl)c1>>COc1ccc2nc(S(=O)Cc3nccc(N4CCOCC4)c3Cl)[nH]c2n1,,ClCCl,,,,test
US20070259821A1,CC(=O)OC[C@H]1OC(O)(c2ccc(Br)c(COc3ccccc3)c2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.N#C[Cu]C#N>>CC(=O)OC[C@H]1OC(O)(c2ccc(C#N)c(COc3ccccc3)c2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,CN1CCCC1=O,,,,test
US05338740,CC(=O)Oc1ccc2c(c1)CCC2=O>>CC(=O)Oc1ccc2c(c1)CCC2O,,CO,,[BH4-].[Na+],,test
US20090093483A1,CC(C)COc1ccc2c(c1F)C(C)(C)C(=O)C(C(=O)NCC(=O)OC(C)(C)C)=C2O>>CC(C)COc1ccc2c(c1F)C(C)(C)C(=O)C(C(=O)NCC(=O)O)=C2O,,O=C(O)C(F)(F)F,,,,test
US20120252818A1,CC(=O)OC(C)=O.COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(OC)c(Sc3nc(N)cc(N)n3)c(OC)n2)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(OC)c(Sc3nc(NC(C)=O)cc(NC(C)=O)n3)c(OC)n2)cc1,CN(C)c1ccncc1,CC(=O)OC(C)=O,,,,test
US20080021053A1,BrCc1cccc(Br)c1.CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)NC1c1ccc(C#N)cc1>>CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(Cc2cccc(Br)c2)C1c1ccc(C#N)cc1,,C1CCOC1,CCCCC,[H-].[Na+],,test
US20040077877A1,CN(C)CC(=O)Nc1cccc(-c2nn(C3CCCCO3)c3ccc(C(N)=O)cc23)c1>>CN(C)CC(=O)Nc1cccc(-c2n[nH]c3ccc(C(N)=O)cc23)c1,,Cc1ccccc1,,,,test
US20030078251A1,COC(=O)c1cc(NC(=O)C[C@H]2O[C@@H](c3cccc(C)c3C)c3cc(Cl)ccc3N(CC(C)(C)COC(C)=O)C2=O)ccc1F>>CCC(C)C[C@@H]1O[C@H](CC(=O)Nc2ccc(F)c(C(=O)O)c2)C(=O)N(CC(C)(C)CO)c2ccc(Cl)cc21,,O,,CCO,[Na+].[OH-],test
US04261995,COC(=O)N=C(NC(=O)OC)SC.COc1cccc(C(CN)CN)c1>>COC(=O)NC1=NCC(c2cccc(OC)c2)CN1,,CO,,,,test
US20060128793A1,COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CC[C@H](O)[C@@]2(C)C[C@H]1OC(C)=O.N#CCCNCc1ccccc1>>COCC1OC(=O)C(=CN(CCC#N)Cc2ccccc2)C2=C(O)C(=O)C3=C(C(OC(C)=O)CC4(C)C(O)CCC34)C21C,,ClCCl,,,,test
US20130143863A1,CC(C)c1ncc[nH]1.ClCc1cncc(Br)c1>>CC(C)c1nccn1Cc1cncc(Br)c1,,CN(C)C=O,,[H-].[Na+],,test
US20100063066A1,CC(C)(C)OC(=O)n1nc(CCCN)c2c(Nc3c(-c4ncccn4)oc4cnccc34)cccc21>>NCCCc1n[nH]c2cccc(Nc3c(-c4ncccn4)oc4cnccc34)c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080146587A1,CC(C)(C)OC(=O)N1CCN(c2cccc3c(Cc4ccccc4)c(S(C)(=O)=O)n(C(=O)OC(C)(C)C)c23)CC1>>CS(=O)(=O)c1[nH]c2c(N3CCNCC3)cccc2c1Cc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070167443A1,Cc1cccc(C(=O)C2CNc3ccccc3C2=O)c1.Cc1cccc(CBr)c1>>Cc1cccc(Cn2cc(C(=O)c3cccc(C)c3)c(=O)c3ccccc32)c1,,CN(C)C=O,,[H-].[Na+],,test
US20060089347A1,CCI.COc1ccc2c(c1)CCCNC2=O>>CCN1CCCc2cc(OC)ccc2C1=O,,C1CCOC1,,[H-].[Na+],,test
US20130022587A1,N[C@@H]1CC[C@@H](Oc2ccccc2)CC1.[C-]#[N+]C(=CN(C)C)C(=O)OCC>>CCOC(=O)c1cn([C@@H]2CC[C@@H](Oc3ccccc3)CC2)cn1,,CCCCO,,CCN(CC)CC,Cl,test
US20100311730A1,CC(C)(C)OC(=O)N1CCCC(CNc2cc(Nc3cnc(C#N)cn3)ncc2-n2ccc(CN3CCOCC3)c2)C1>>N#Cc1cnc(Nc2cc(NCC3CCCNC3)c(-n3ccc(CN4CCOCC4)c3)cn2)cn1,,CO,,,,test
US20090062251A1,CN[C@H](C)C(=O)O.Cn1c2c(c3cc(C(=O)O)ccc31)CC(C1CCOCC1)CC2>>C[C@H](C(=O)O)N(C)C(=O)c1ccc2c(c1)c1c(n2C)CCC(C2CCOCC2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130123232A1,CC(C)(C)OC(=O)N1CCc2cc(C(=O)N3CC(N4CCN(C(=O)c5nccs5)CC4)C3)ccc2C1>>O=C(c1ccc2c(c1)CCNC2)N1CC(N2CCN(C(=O)c3nccs3)CC2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140243368A1,COP(=O)(OC)C(=[N+]=[N-])C(C)=O.C[C@@H]1CC[C@@H](C=O)CN1C(=O)c1ccccc1-n1nccn1>>C#C[C@@H]1CC[C@@H](C)N(C(=O)c2ccccc2-n2nccn2)C1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20110015175A1,CI.NC(=S)Nc1cc(F)c(-n2cnc(Cl)c2)c(F)c1>>CSC(=N)Nc1cc(F)c(-n2cnc(Cl)c2)c(F)c1.I,,CCO,,,,test
US20130267524A1,C[C@@H](c1cc2ccc(F)cc2nc1-c1ccccn1)N1C(=O)c2ccccc2C1=O>>C[C@H](N)c1cc2ccc(F)cc2nc1-c1ccccn1,,CCO,,NN,,test
US20090215843A1,Br.OCCCCCc1ccccc1>>BrCCCCCc1ccccc1,,CCOC(C)=O,,,,test
US20090054609A1,CC(=O)c1cccc(C(C)=Nc2c(C)cc(C)cc2Cl)n1.CC(C)c1cccc(C(C)C)c1N>>CC(=Nc1c(C)cc(C)cc1Cl)c1cccc(C(C)=Nc2c(C(C)C)cccc2C(C)C)n1,,C1CCOC1,,,,test
US20050245518A1,Clc1ccnc(Cl)n1.OB(O)c1ccsc1>>Clc1nccc(-c2ccsc2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20060142337A1,CC(=O)N1CCNCC1.C[C@@H](O[C@H]1CCNC[C@H]1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.Cl.O=C(Cl)CCl>>CC(=O)N1CCN(CC(=O)N2CC[C@H](O[C@H](C)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](c3ccccc3)C2)CC1.Cl,,CN(C)C=O,O,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20110105463A1,CCOC(=O)C1CCOc2cc(Oc3ccc(C(=O)NCCc4ccc(Cl)cc4OC)cc3)c(Cl)cc21>>COc1cc(Cl)ccc1CCNC(=O)c1ccc(Oc2cc3c(cc2Cl)C(C(=O)O)CCO3)cc1,,C1CCOC1,CCO,[Na+].[OH-],,test
USRE029439,NC(=NO)c1ccccc1.S=C=S>>Sc1nc(-c2ccccc2)ns1,,CCO,,C[O-].[Na+],,test
US07700552B2,CN(C)C(N)=S.O=C(O)C(=O)CBr>>CN(C)c1nc(C(=O)O)cs1,,C1CCOC1,,,,test
US06448244B1,CC(=O)NC(C)C(C)n1ncn(-c2ccc(N3CCN(c4ccc(O)cc4)CC3)cc2)c1=O>>CC(N)C(C)n1ncn(-c2ccc(N3CCN(c4ccc(O)cc4)CC3)cc2)c1=O,,Cl,,,,test
US20030064991A1,CC(Cl)Cl.CC=O.Cc1[nH]c2ccc(CN)cc2c1C(=O)OCc1ccccc1>>CCN(CC)Cc1ccc2[nH]c(C)c(C(=O)OCc3ccccc3)c2c1,,CC(Cl)Cl,,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20040259923A1,Nc1nc(/C=C/c2ccc([N+](=O)[O-])cc2)cs1.O=C(Cl)c1ccccc1>>O=C(Nc1nc(/C=C/c2ccc([N+](=O)[O-])cc2)cs1)c1ccccc1,,CCOC(C)=O,,CN(C)c1ccccc1,,test
US20160107997A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)CNc1cccc2c1CNCC2>>CCOC(=O)CNc1cccc2c1CN(C(=O)OC(C)(C)C)CC2,,ClCCl,,,,test
US20090227541A1,CCOC(=O)CCCOc1cccc2c1B(O)OC2C[N+](=O)[O-]>>O=C(O)CCCOc1cccc2c1B(O)OC2C[N+](=O)[O-],,CO,O,[Na+].[OH-],,test
US04963686,CC1(C)C(=O)Nc2cc(N)c([N+](=O)[O-])cc21.CO>>CC1(C)C(=O)NC(=O)c2ccccc21,[Pd],,,,,test
US20030055085A1,C[Si](C)(C)N=[N+]=[N-].N#Cc1cc(F)cc(-c2nc(-c3ccc(F)cn3)no2)c1>>Fc1ccc(-c2noc(-c3cc(F)cc(-c4nnn[nH]4)c3)n2)nc1,,Cc1ccccc1,,C[Al](C)C,,test
US05874440,CCCOc1ccccc1-c1nc(O)cc(Cl)n1.NCCCO>>CCCOc1ccccc1-c1nc(NCCCO)cc(=O)[nH]1,,CCCO,,,,test
US08507476B2,CCOC(=O)N1CCn2c(nc(-c3ccncn3)cc2=O)C(NC(=O)c2ccc(Br)cc2)C1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>CCOC(=O)N1CCn2c(nc(-c3ccncn3)cc2=O)C(NC(=O)c2ccc(-c3cnn(C)c3)cc2)C1,,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20150232464A1,C=O.COC(=O)Cc1ccc(C)cn1.C[O-]>>COC(=O)C(CO)(CO)c1ccc(C)cn1,,CC(=O)O,,CN(C)C=O,,test
US20130079302A1,CC(C)(C)C#Cc1cccc(N)c1>>CC(C)(C)CCC1CCCC(N)C1,[Ru],C1CCOC1,,[H][H],,test
US20080214613A1,CCOc1ccc(Cc2nc3cc([N+](=O)[O-])ccc3n2CCC2CCCN2C)cc1.CSC(=N)c1cccs1>>CCOc1ccc(Cc2nc3cc(NC(=N)c4cccs4)ccc3n2CCC2CCCN2C)cc1,[Pd],CCO,,I,,test
US20040254166A1,[N-]=[N+]=NCC(F)(F)c1cccc2cccnc12>>NCC(F)(F)c1cccc2cccnc12,[Pd],CO,,,,test
US20050245503A1,Cc1cccc2c1CCc1ccncc1C2N.S=C=S>>Cc1cccc2c1CCc1ccncc1C2N=C=S,,C1CCOC1,,ClCCCl,,test
US20150141413A1,CCOC(=O)CS.COc1ccc(CN2[C@](C)(c3cc(Br)ccc3F)COS2(=O)=O)c(OC)c1>>CCOC(=O)CSC[C@](C)(NCc1ccc(OC)cc1OC)c1cc(Br)ccc1F,,CN(C)C=O,,CN(C)C(=N)N(C)C,,test
US20100152045A1,OCCCl.Oc1c(Cl)cc(OCc2ccccc2)cc1Cl>>OCCOc1c(Cl)cc(OCc2ccccc2)cc1Cl,,CN(C)C=O,Cl,O=C([O-])[O-].[K+].[K+],,test
US20100331293A1,COc1cncc(-c2ncc(N3CCOCC3)cc2Nc2c(C)c(-c3ccccn3)nc3cc(F)cc(F)c23)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1cncc(-c2ncc(N3CCOCC3)cc2N(C(=O)C(F)(F)F)c2c(C)c(-c3ccccn3)nc3cc(F)cc(F)c23)c1,,ClCCl,,CCN(CC)CC,,test
US20070184024A1,CC(C)S(N)(=O)=O.COC(=O)C1=Cc2cc(OC)ccc2-c2c(C3CCCCC3)c3ccc(C(=O)O)cc3n2C1>>COC(=O)C1=Cc2cc(OC)ccc2-c2c(C3CCCCC3)c3ccc(C(=O)NS(=O)(=O)C(C)C)cc3n2C1,,C1CCOC1,CCOC(C)=O,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US05563162,CN(C(=O)CN1C(=O)c2ccccc2C1=O)c1ccc(Cl)c(CO)c1Cl.CS(=O)(=O)Cl>>CN(C(=O)CN1C(=O)c2ccccc2C1=O)c1ccc(Cl)c(COS(C)(=O)=O)c1Cl,,ClCCl,,CCN(CC)CC,,test
US20130102776A1,CC(C)(C)OC(=O)N1CCN(Cc2c(O)ccc3c2O/C(=C\c2c[nH]c4c(OCc5ccccc5)cccc24)C3=O)CC1.Cl.ClCCl>>Cl.Cl.O=C1/C(=C/c2c[nH]c3c(OCc4ccccc4)cccc23)Oc2c1ccc(O)c2CN1CCNCC1,,C1COCCO1,ClCCl,,,test
US20150329447A1,CC(c1ccccc1)C1(Cc2c(Br)c(Br)c(Br)c(Br)c2Br)C=CC(Cc2c(Br)c(Br)c(Br)c(Br)c2Br)C(Cc2c(Br)c(Br)c(Br)c(Br)c2Br)(Cc2c(Br)c(Br)c(Br)c(Br)c2Br)C1(Cc1c(Br)c(Br)c(Br)c(Br)c1Br)Cc1c(Br)c(Br)c(Br)c(Br)c1Br>>CC(c1ccccc1)c1ccccc1,,CC(Cl)Cl,,BrBr,,test
US20100004269A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.O=[N+]([O-])c1ccc(O)cc1F>>O=[N+]([O-])c1ccc(OS(=O)(=O)C(F)(F)F)cc1F,,ClCCl,,CCN(CC)CC,,test
US20110105509A1,Cc1[nH]c2ccccc2c1I.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>Cc1c(I)c2ccccc2n1S(=O)(=O)c1ccc(C(F)(F)F)cc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20160272655A1,CCOC(=O)CC(=O)CCl.Nc1nnc(C(F)(F)F)s1>>CCOC(=O)Cc1cn2nc(C(F)(F)F)sc2n1,,CCO,,,,test
US20090030009A1,O=C(Nc1cccc(C(F)(F)F)c1)c1noc2cc(OCc3ccccc3)ccc12>>O=C(Nc1cccc(C(F)(F)F)c1)c1noc2cc(O)ccc12,[Pd],C1CCOC1,,CCCCCC,,test
US08754079B2,CO[C@@H]1CCCC[C@H]1Oc1cc(F)ccc1[N+](=O)[O-]>>CO[C@@H]1CCCC[C@H]1Oc1cc(F)ccc1N,[Pd],CO,,[H][H],,test
US20040116490A1,COC(=O)CSc1cccs1.NN>>NNC(=O)CSc1cccs1,,CO,,,,test
US05693379,CCCCCCCCCCCCCCCCCCO.O=C(Cl)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>CCCCCCCCCCCCCCCCCCOC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,O,test
US05693846,CCC(C)(C)c1ccc(OCCCCNC(=O)c2ccc3ccccc3c2O)c(C(C)(C)CC)c1.ClSc1nnnn1-c1ccccc1>>CCC(C)(C)c1ccc(OCCCCNC(=O)c2cc(Sc3nnnn3-c3ccccc3)c3ccccc3c2O)c(C(C)(C)CC)c1,,ClC(Cl)(Cl)Cl,,,,test
US20120225854A1,CC(C)(C)OC(=O)N1CCN(c2ncc(C(O)(C(F)(F)F)C(F)(F)F)cn2)[C@@H](CN(c2ccccc2)S(C)(=O)=O)C1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)s1>>CS(=O)(=O)N(C[C@H]1CN(S(=O)(=O)c2ccc([N+](=O)[O-])s2)CCN1c1ncc(C(O)(C(F)(F)F)C(F)(F)F)cn1)c1ccccc1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20160039838A1,C1CO[C@H]2CNC[C@H]2O1.CC1(COc2cc3ncnc(Nc4ccc(F)c(Cl)c4)c3cc2NC(=O)/C=C/CBr)COC1>>CC1(COc2cc3ncnc(Nc4ccc(F)c(Cl)c4)c3cc2NC(=O)/C=C/CN2C[C@H]3OCCO[C@H]3C2)COC1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,O,test
US04940710,C=O.CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(COc4ccccc4)C3)cc21>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)C(COc4ccccc4)C3)cc21,,O=CO,,,,test
US04616020,C=CCCn1cnc2c1c(=O)n(CCCC)c(=O)n2CCCC.O=C(OO)c1cccc(Cl)c1>>CCCCn1c(=O)c2c(ncn2CCC2CO2)n(CCCC)c1=O,,ClC(Cl)Cl,,,,test
US20120077793A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OS(=O)(=O)C(F)(F)F)cc1F)C(=O)N1CCC[C@H]1C#N.CC(C)OC(=O)N1CCC(C(C)Oc2ccc(B3OC(C)(C)C(C)(C)O3)cn2)CC1>>CC(C)OC(=O)N1CCC([C@H](C)Oc2ccc(-c3ccc(CC(NC(=O)OC(C)(C)C)C(=O)N4CCC[C@H]4C#N)c(F)c3)cn2)CC1,,CN(C)C=O,O,CCN(CC)CC,,test
US05804532,CCC(=O)C(C(=O)OC(C)(C)C)C(=O)c1ccc(S(C)(=O)=O)cc1Cl>>CCC(=O)CC(=O)c1ccc(S(C)(=O)=O)cc1Cl,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100305104A1,COC(=O)c1ccc(Br)c(C(F)(F)F)c1.Cc1cscc1B(O)O>>COC(=O)c1ccc(-c2cscc2C)c(C(F)(F)F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[K+].[K+],,test
US20130245035A1,COC(=O)c1cc(C2CC2)c2c(C)c(-c3ccc4c(c3)NC(=O)C(NC(=O)OC(C)(C)C)C4)ccn2c1=O>>Cc1c(-c2ccc3c(c2)NC(=O)C(NC(=O)OC(C)(C)C)C3)ccn2c(=O)c(C(=O)O)cc(C3CC3)c12,,CO,,O,[Na+].[OH-],test
US20120258950A1,CCOC(=O)Cc1ccn2ccnc2c1>>O=C(O)Cc1ccn2ccnc2c1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20160060216A1,COC(=O)c1ccc(/C=C\CN2C(=O)CC[C@@H]2C(=O)OC(C)(C)C)s1>>COC(=O)c1ccc(/C=C\CN2C(=O)CC[C@@H]2C(=O)O)s1,,CCO,ClCCl,O=C(O)C(F)(F)F,,test
US20110152290A1,COc1c(OC(C)=O)cc(C(=O)O)cc1[N+](=O)[O-]>>COc1c(N)cc(C(=O)O)cc1OC(C)=O,[Pd],CCO,CO,Cl,[H][H],test
US20160002175A1,Nc1nc(Cl)cc(NCCc2ccc(Cl)cc2)n1.OB(O)c1cccc(C(F)(F)F)c1>>Nc1nc(NCCc2ccc(Cl)cc2)cc(-c2cccc(C(F)(F)F)c2)n1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US05711939,CC(C)CCCCC(=O)O.CCCCC(CC)CO>>CCCCC(CC)COC(=O)CCCCC(C)C,,Cc1ccccc1,,O=S(=O)(O)O,,test
US20080009479A1,N#Cc1ccc(C(=O)O)cc1.c1cc2c(cc1OCC1CCNCC1)CCN(CC1CC1)CC2>>N#Cc1ccc(C(=O)N2CCC(COc3ccc4c(c3)CCN(CC3CC3)CC4)CC2)cc1,,CO,ClCCl,,,test
US20040058903A1,N#Cc1ccc(N)cc1.O=C(Cl)c1ccccc1-c1ccc(C(F)(F)F)cc1>>N#Cc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1,,ClCCl,,CCN(CC)CC,O,test
US20090042900A1,O=C(O)C1CCC(c2ccc(Cl)cc2)CC1>>OCC1CCC(c2ccc(Cl)cc2)CC1,,O,,,,test
US20030114666A1,COCNC(=O)C1CC(=O)N([C@@H](C)c2ccccc2)C1.Fc1ccccc1Br>>C[C@@H](c1ccccc1)N1CC(C(=O)c2ccccc2F)CC1=O,,C1CCOC1,CCOC(C)=O,[Li]CCCC,,test
US20140128425A1,BrBr.Nc1ncccc1OCc1c(F)cccc1F>>Nc1ncc(Br)cc1OCc1c(F)cccc1F,,CC(=O)O,CCOC(C)=O,O=S(=O)(O)O,,test
US03953500,C1CSCSC1.O=C1CCc2c1cccc2C(=O)c1ccccc1>>O=C(c1ccccc1)c1cccc2c1CCC2(O)C1SCCCS1,,CCCCCC,,C1CCOC1,[Li]CCCC,test
US04920120,C1CNCCN1.Cc1c(F)c(F)c(Cl)c2c1c(=O)c(C(=O)O)cn2C1CC1>>Cc1c(F)c(N2CCNCC2)c(Cl)c2c1c(=O)c(C(=O)O)cn2C1CC1,,CC#N,,,,test
US20050277652A1,C1CCNC1.Nc1cc(Oc2ccc(N)c(Cl)c2)ccn1.S=C(Cl)Oc1ccccc1>>Nc1ccc(Oc2ccnc(NC(=S)N3CCCC3)c2)cc1Cl,,C1CCOC1,,CCN(CC)CC,,test
US20070287706A1,CC(C)NCc1cc2cccc(F)c2[nH]c1=O.CN1CCOc2cc(S(=O)(=O)Cl)ccc21>>CC(C)N(Cc1cc2cccc(F)c2[nH]c1=O)S(=O)(=O)c1ccc2c(c1)OCCN2C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150080438A1,COc1ccc2c(c1)CCCC(c1ccc(F)c(OC)c1)=C2C#CCCCO>>COc1ccc2c(c1)CCCC(c1ccc(F)c(OC)c1)=C2CCCCCO,[Pd],,,,,test
US20090226398A1,COc1ccc(-c2ccc(Cn3cc4nc(-c5cccc(F)c5F)nc-4cn3)cc2[N+](=O)[O-])c(C(F)(F)F)c1>>COc1ccc(-c2ccc(Cn3cc4nc(-c5cccc(F)c5F)nc-4cn3)cc2N)c(C(F)(F)F)c1,[Pd],CO,ClCCl,,,test
US20070259864A1,CCOC(=O)CCc1ccc(C#N)cc1>>N#Cc1ccc(CCCO)cc1,,CCOCC,,CO,[BH4-].[Li+],test
US20160185780A1,CC(=O)NCC1(c2ccc(Cl)cc2)CCN(C(=O)OC(C)(C)C)CC1>>CC(=O)NCC1(c2ccc(Cl)cc2)CCNCC1,,C1COCCO1,,Cl,,test
US20160229837A1,CCC1CNCCC1N(C)c1nc(Nc2ccc3c(C)n(C)nc3c2)ncc1Cl.N#Cc1ccc(Cl)nc1>>CCC1CN(c2ccc(C#N)cn2)CCC1N(C)c1nc(Nc2ccc3c(C)n(C)nc3c2)ncc1Cl,,CCO,,,,test
US20100160280A1,Fc1ccccn1.Nc1ccc(O)c(F)c1>>Oc1ccc(Nc2ccccn2)cc1F,,CCOC(C)=O,,CN1CCCC1=O,,test
US03931217,O=C(O)c1ccccc1C(=O)c1ccc(Br)cc1>>O=Cc1ccccc1C(=O)c1ccc(Br)cc1,,C1CCOC1,,[H-].[Na+],,test
US05157041,CC(C)(C)N1C[C@@H](O)C[C@@]1(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(N)=O.N#N>>CC(C)(C)N1C[C@@H](O)C[C@@]1(C[C@@H](O)[C@@H](N)Cc1ccccc1)C(N)=O.N#N,[Pd],CCO,,,,test
US20060019964A1,CC(C)(C)OC(=O)N1CCN(c2ccc(OC3CCNCC3)cc2)CC1.O=C1CCC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(OC3CCN(C4CCC4)CC3)cc2)CC1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04626533,CC(=O)NCC1=C(C(=O)O)N2C(=O)C(NC(=O)CBr)[C@H]2SC1.Sc1nnc(COc2ccc(Cl)cc2)o1>>CC(=O)NCC1=C(C(=O)O)N2C(=O)C(Sc3nnc(COc4ccc(Cl)cc4)o3)[C@H]2SC1NC(C)=O,,CCOCC,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130150361A1,NNc1ccc(F)cn1.O=C(O)C1CCCCC1>>O=C(NNc1ccc(F)cn1)C1CCCCC1,,O,,ClCCCl,On1nnc2ccccc21,test
US20070066624A1,CC(C)(C)OC(=O)CBr.Cc1nc(Sc2ccc(O)cc2)ccc1CN1CCC(N2C(=O)NC[C@H]2c2ccccc2)CC1>>Cc1nc(Sc2ccc(OCC(=O)OC(C)(C)C)cc2)ccc1CN1CCC(N2C(=O)NC[C@H]2c2ccccc2)CC1,,C1CCOC1,,[H-].[Na+],,test
US20150133428A1,CCOC(=O)c1c(I)nn(CC(NC(=O)OC(C)(C)C)C2CC2)c1C(=O)OCC>>CCOC(=O)c1c(I)nn2c1C(=O)NC(C1CC1)C2,,C1COCCO1,,Cl,,test
US05807857,CCC(C(=O)Cl)C(=O)Cl.CCOCC.c1ccc(CN2CCNCC2)cc1>>CCOC(=O)CC(=O)N1CCN(Cc2ccccc2)CC1,,CCOCC,ClCCl,CCN(CC)CC,O,test
US06288082B1,C1CSCCN1.COc1cc2c(Nc3ccc4cn[nH]c4c3)c(C#N)cnc2cc1OCCCl>>COc1cc2c(Nc3ccc4cn[nH]c4c3)c(C#N)cnc2cc1OCCN1CCSCC1,,COCCOC,,[I-].[Na+],,test
US20020193614A1,O=C(OC1CCC(O)C1)c1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>[N-]=[N+]=NC1CCC(OC(=O)c2ccccc2)C1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120157430A1,CC(C)(C)OC(=O)N1CCC(n2cc(B3OC(C)(C)C(C)(C)O3)cn2)CC1.COc1c(C(C)Nc2ncnc3c2ncn3C2CCCCO2)cc(Cl)c(C)c1Br>>COc1c(C(C)Nc2ncnc3c2ncn3C2CCCCO2)cc(Cl)c(C)c1-c1cnn(C2CCN(C(=O)OC(C)(C)C)CC2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20050038248A1,COc1ccc(NS(=O)(=O)c2ccccc2[N+](=O)[O-])cc1>>COc1ccc(NS(=O)(=O)c2ccccc2N)cc1,[Pd],CC(=O)O,CCO,,,test
US20150336928A1,N#CC1=Cc2cccc3cccc1c23>>N#CC1Cc2cccc3cccc1c23,[Pd],CCO,,,,test
US20160221972A1,COC(=O)c1ccc2c(c1)O[C@@H](C)CNC2.COc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1ccc2c(c1)O[C@@H](C)CN(S(=O)(=O)c1ccc(OC)cc1)C2,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20150376130A1,Nc1ccc(Cl)cc1.O=C(O)c1ccncc1F>>O=C(O)c1ccncc1Nc1ccc(Cl)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20070078121A1,CC(C)(C)OC(=O)N1Cc2cc(-n3nc(C(C)(C)C)cc3NC(=O)Nc3cccc(Cl)c3Cl)ccc2C[C@H]1C(N)=O>>CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)n(-c2ccc3c(c2)CN[C@H](C(N)=O)C3)n1,,C1COCCO1,Cl,,,test
US05021478,CCCCNC1CC(C)(C)N(OC)C(C)(C)C1.O=C(Cl)CCl>>CCCCN(C(=O)CCl)C1CC(C)(C)N(OC)C(C)(C)C1,,CCOCC,ClCCl,,,test
US20090286827A1,COC1=NCCCC1.NNC(=O)c1cnc(Nc2ccc(Cl)cc2)c(Cl)c1>>Clc1ccc(Nc2ncc(-c3nnc4n3CCCC4)cc2Cl)cc1,,CCO,,,,test
US05057513,ClCc1cccnc1.O=C1C[C@]2(CCCC[C@H]2Cc2ccccc2)S(=O)(=O)CCN1>>O=C1C[C@]2(CCCC[C@H]2Cc2ccccc2)S(=O)(=O)CCN1Cc1cccnc1,,CCOC(C)=O,CS(C)=O,[H-].[Na+],,test
US05998436,CC(C)(C)Nc1nc(F)c(Cl)cc1F.NCc1ccccc1>>CC(C)(C)Nc1nc(NCc2ccccc2)c(Cl)cc1F,,CN1CCCC1=O,,,,test
US20120165304A1,CCOC(=O)C1CCN(C(=O)OCc2ccccc2)CCC1=O.Nc1cc[nH]n1>>O=C(OCc1ccccc1)N1CCc2nc3ccnn3c(O)c2CC1,,CC(=O)O,,,,test
US20110124686A1,CN(C)C=O.COc1ccc(Cl)cc1F>>COc1ccc(Cl)c(C=O)c1F,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20080269211A1,CC(C)I.CCOC(=O)c1n[nH]c2ccc(F)cc12>>CCOC(=O)c1nn(C(C)C)c2ccc(F)cc12,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20090054508A1,COc1c(OCCC23C=CC=CC2C(=O)NC3=O)ccc(C(OC)OC)c1[N+](=O)[O-].NN>>COc1c(OCCN)ccc(C(OC)OC)c1[N+](=O)[O-],,CCO,,O,O,test
US20090221587A1,CN.O=c1oc(-c2cc(Br)nn2-c2ncccc2Cl)nc2cc3ccc(C(F)(F)F)nc3cc12>>CNC(=O)c1cc2nc(C(F)(F)F)ccc2cc1NC(=O)c1cc(Br)nn1-c1ncccc1Cl,,C1CCOC1,,,,test
US20160002269A1,CCNC(=O)[C@H](NC(=O)c1ccc(N=[N+]=[N-])cc1O)[C@H](C)O>>CCNC(=O)[C@@H]1N=C(c2ccc(N=[N+]=[N-])cc2O)O[C@@H]1C,,ClCCl,,O=S(Cl)Cl,,test
US05262441,CCC(C)Oc1ccc(O)c(Cl)c1.ClCc1ccc(Cl)cc1>>CCC(C)Oc1ccc(OCc2ccc(Cl)cc2)c(Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US07135487B2,CC(CNS(=O)(=O)C(C)C)c1ccc(-c2ccc(C=O)cc2)cc1.CCOP(=O)(CC#N)OCC>>CC(CNS(=O)(=O)C(C)C)c1ccc(-c2ccc(C=CC#N)cc2)cc1,,C1CCOC1,O,[H-].[Na+],,test
US08933241B2,C=C(C)c1nc(CCC)n(Cc2ccc(-c3ccccc3-c3nnn[nH]3)cc2)c1C(=O)O.Cc1oc(=O)oc1CCl.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>C=C(C)c1nc(CCC)n(Cc2ccc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc2)c1C(=O)OCc1oc(=O)oc1C,,CC(C)=O,,C1CCC2=NCCCN2CC1,,test
US20040209921A1,Cc1cnc(CN(Cc2nccc3ccccc23)C2CCNCC2)c(C)c1.O=C(NO)Oc1ccccc1>>Cc1cnc(CN(Cc2nccc3ccccc23)C2CCN(C(=O)NO)CC2)c(C)c1,,C1CCOC1,,,,test
US20100081679A1,Cc1ccc(S(=O)(=O)O)cc1.Clc1ncc(Cl)c(Cl)n1.Nc1ccccc1>>O=c1[nH]c(Nc2ccccc2)ncc1Cl,,C1COCCO1,O,[Na+].[OH-],,test
US20140323463A1,CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3nc(Oc4cccc([N+](=O)[O-])c4)cnc3C(N)=O)cc2)CC1.O=C1CCC(=O)N1Cl>>CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3nc(Oc4cccc([N+](=O)[O-])c4)cnc3C(N)=O)cc2Cl)CC1,,ClC(Cl)Cl,,,,test
US05744471,COC(=O)c1nc2cc(Cl)ccc2c(O)c1C(=O)OC.COc1ccc(NN)cc1>>COc1ccc(-n2nc(O)c3c(=O)c4ccc(Cl)cc4[nH]c3c2=O)cc1,,CCO,,CCN(CC)CC,Cl,test
US20110263661A1,C=COC(C)=O.CCOC(=O)c1ccc(O)c(Br)c1>>C=COc1ccc(C(=O)OCC)cc1Br,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20030134836A1,CS(=O)(=O)Cl.NCCOc1cc(NC(=O)c2cccnc2Cl)ccc1C(F)(F)C(F)(F)F>>CS(=O)(=O)NCCOc1cc(NC(=O)c2cccnc2Cl)ccc1C(F)(F)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US06069156,CCCC(=O)C(=CN(C)C)c1ccc(C(=O)OC)cc1[N+](=O)[O-]>>CCCC(=O)Cc1ccc(C(=O)OC)cc1[N+](=O)[O-],,C1COCCO1,,,,test
US05498624,CC(C)(C)O.O=C=Nc1ccccc1>>CC(C)(C)OC(=O)Nc1ccccc1,,Cc1ccccc1,,,,test
US05344845,COc1cc(C=CC(=O)N[C@@H]2CC[C@@H](C)CC2)ccc1O.ClCCCCBr>>COc1cc(C=CC(=O)N[C@@H]2CC[C@@H](C)CC2)ccc1OCCCCCl,,CC(=O)CC(C)C,,O=C([O-])[O-].[K+].[K+],,test
US06136823,CCOC(=O)c1cn(-c2cc(NC(=O)OC(C)(C)C)c(F)cc2F)c2c(C)c(N)c(F)cc2c1=O>>Cc1c(N)c(F)cc2c(=O)c(C(=O)O)cn(-c3cc(N)c(F)cc3F)c12,,O,,Cl,,test
US20040132720A1,C=O.C[C@H]1CN(c2ccc3occ(C(=O)N(C)C)c3c2)C[C@@H](C)N1>>C[C@H]1CN(c2ccc3occ(C(=O)N(C)C)c3c2)C[C@@H](C)N1C,,CO,,[BH3-]C#N.[Na+],,test
US20150315188A1,Cc1ccc2c(c1)c1c(n2CC(O)c2ccncc2)CCN2CCCC12.O=C(OO)c1cccc(Cl)c1>>Cc1ccc2c(c1)c1c(n2CC(O)c2ccncc2)CC[N+]2([O-])CCCC12,,ClCCl,,O=C([O-])O.[Na+],,test
US20110224262A1,COCCc1[nH]ncc1-c1ccccc1.O=C1CCC(=O)N1Br>>COCCc1[nH]nc(Br)c1-c1ccccc1,,CO,,,,test
US20150011528A1,Cc1ccc(C(=O)Cl)cc1.Cc1ccc2nc(N)sc2c1>>Cc1ccc(C(=O)Nc2nc3ccc(C)cc3s2)cc1,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04288437,CNC(=O)NC.O=C(c1ccccc1)c1sc2ccccc2c1O>>CN/C(=C1/Sc2ccccc2C1=O)c1ccccc1,,CCOC(C)=O,,,,test
US20100130470A1,O=C1CNCc2cc(Br)cnc2N1>>Brc1cnc2c(c1)CNCCN2,,C1CCOC1,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050245547A1,COc1cc2nccc(Cl)c2cc1OC.O=C(O)c1cc2cc(O)ccc2o1>>COc1cc2nccc(Oc3ccc4oc(C(=O)O)cc4c3)c2cc1OC,,CS(C)=O,O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20070213338A1,C[C@H](N)c1cccc(C(C)(C)O[SiH2]C(C)(C)C)n1.O=CCc1ccccc1>>C[C@H](NCCc1ccccc1)c1cccc(C(C)(C)O[SiH2]C(C)(C)C)n1,,CC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05883262,Clc1ncccn1.OCCOc1ccc(Cn2cccn2)cc1>>c1cnc(OCCOc2ccc(Cn3cccn3)cc2)nc1,,CN(C)C=O,,[H-].[Na+],,test
US20140135318A1,CCCCN(CCCC)C(=O)c1nn(-c2ccc(C(=O)OCc3ccccc3)cc2C(=O)N2CCc3ccccc3C2)c(C)c1Br>>CCCCN(CCCC)C(=O)c1nn(-c2ccc(C(=O)O)cc2C(=O)N2CCc3ccccc3C2)c(C)c1Br,,C1CCOC1,,Cl,[Na+].[OH-],test
US20150038510A1,CC(C)(C)n1cnc2cc(Br)ccc21.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(C)(C)n1cnc2cc(B3OC(C)(C)C(C)(C)O3)ccc21,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20140045862A1,COc1ccc(CN(c2ccncn2)S(=O)(=O)c2cc(Cl)c(O[C@H]3CC(F)(F)C[C@@H]3c3ccnn3C)cc2F)c(OC)c1>>Cn1nccc1[C@H]1CC(F)(F)C[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US04798619,CC(C)C(C)(NC(=O)c1nc2ccccc2cc1C(=O)O)C(N)=O>>CC(C)C1(C)N=C(c2nc3ccccc3cc2C(=O)O)NC1=O,,O,,Cl,[Na+].[OH-],test
US20130336920A1,[N-]=[N+]=NCCOCCOCCOCCOCC#Cc1cccc(C(=O)OCc2ccccc2)c1>>NCCOCCOCCOCCOCC#Cc1cccc(C(=O)OCc2ccccc2)c1,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20030166658A1,CC(=O)c1ccncn1.NNc1nc2ccccc2[nH]1>>CC(=NNc1nc2ccccc2[nH]1)c1ccncn1,CC(=O)O,CO,,,,test
US20070149801A1,CC(=O)Nc1ccc(O)cc1.O=C(Cl)CCCO[N+](=O)[O-]>>CC(=O)Nc1ccc(OC(=O)CCCO[N+](=O)[O-])cc1,,C1CCOC1,,[H-].[Na+],,test
US04472399,CC1CCC(Br)(Br)c2nc3ccccc3c(=O)n21.NNc1ccccc1>>CC1CCC(=NNc2ccccc2)c2nc3ccccc3c(=O)n21,,CCO,,,,test
US20150133457A1,COCCn1ccc2c([N+](=O)[O-])cccc21>>COCCn1ccc2c(N)cccc21,O=[Pt]=O,CCO,,[H][H],,test
US04281000,CN(C)C=CC(=O)c1ccsc1.Nc1n[nH]cc1Br>>Brc1cnn2c(-c3ccsc3)ccnc12,,CC(=O)O,,,,test
US20140140955A1,COc1nc(N)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@@]1(C)O.O=C1CCC(=O)N1I>>COc1nc(N)nc2c1nc(I)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@@]1(C)O,,C1CCOC1,,,,test
US20120252802A1,COc1cccc(CC(C)(C)NC(=O)NC(C)(C)Cc2cccc(OC)c2)c1>>COc1cccc(CC(C)(C)N)c1,,O,OCCO,[K+].[OH-],,test
US06518458B1,NCC(=O)NC1CCCCC1.NN=Cn1cccn1>>NN=CNCC(=O)NC1CCCCC1,,C1COCCO1,,Cl,,test
US06235789B1,COc1ccc2c(c1)/C(=C/CNC(C)=O)CCC2>>COc1ccc2c(c1)C(CCNC(C)=O)CCC2,[Pd],CCO,,,,test
US20110071150A1,CCOC(=O)C(Br)C(C)C(F)(F)F.NC(=S)c1cccnc1>>CC(c1sc(-c2cccnc2)nc1O)C(F)(F)F,,CCO,,c1ccncc1,,test
US05286902,CC(C)c1ccc2cc(O)ccc2c1.COS(=O)(=O)OC>>COc1ccc2cc(C(C)C)ccc2c1,,O,,[Na+].[OH-],,test
US20150018335A1,C1CCNCC1.O=Cc1ccc(Br)cc1F>>O=Cc1ccc(Br)cc1N1CCCC1,,CCOC(C)=O,,CC(=O)N(C)C,,test
US05166347,CC(C)OC(=NC#N)c1cccnc1.NCCc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1>>N#CNC(=NCCc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1)c1cccnc1,,CO,,CCN(CC)CC,Cl,test
US20090318690A1,CN(C)Cc1c(OCc2ccc(C#N)cc2)ccc2c(CCC3CCN(CC4(CO[Si](c5ccccc5)(c5ccccc5)C(C)(C)C)CC4)CC3)noc12>>CN(C)Cc1c(OCc2ccc(C#N)cc2)ccc2c(CCC3CCN(CC4(CO)CC4)CC3)noc12,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05688815,CC(=O)OCCn1ccc(=O)c(O)c1Cc1ccc(F)cc1>>O=c1ccn(CCO)c(Cc2ccc(F)cc2)c1O,,CO,,N,,test
US20030153568A1,CCNC(=O)Nc1nc2c(s1)-c1[nH]ccc1CC2>>CCNC(=O)Nc1nc2ccc3cc[nH]c3c2s1,,Cc1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US04695654,CS(=O)(=O)OCCC(F)(F)COCc1ccccc1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1CCC(F)(F)COCc1ccccc1,,CN(C)C=O,,[K],,test
US06936602B1,CCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3C=O)cc1>>CCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3C=O)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20150031709A1,Cc1cc(Br)cs1.OB(O)c1ccccc1>>c1ccc(-c2cccs2)cc1,,C1COCCO1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,O=C([O-])[O-].[Na+].[Na+],test
US05106871,COCOc1ccc(C=CC(=O)c2c(OCOC)cc(OCOC)c(CC=C(C)C)c2O)cc1OC>>COCOc1ccc(CCC(=O)c2c(OCOC)cc(OCOC)c(CCC(C)C)c2O)cc1OC,[Pd],CCOC(C)=O,,,,test
US20140275080A1,CC1(C)CC(C(N)=O)C1.Cn1cc(-c2cc(Oc3ccc(N)nc3)ccn2)cn1.O=C(Cl)C(=O)Cl>>Cn1cc(-c2cc(Oc3ccc(NC(=O)NC(=O)C4CC(C)(C)C4)nc3)ccn2)cn1,,C1CCOC1,ClCCCl,c1ccncc1,,test
US20130096113A1,C1COCCN1.O[C@@H]1CCCC[C@H]1Nc1nc2ccc(Cn3cnc4cc(I)cnc43)cc2s1>>O[C@@H]1CCCC[C@H]1Nc1nc2ccc(Cn3cnc4cc(N5CCOCC5)cnc43)cc2s1,[Cu]I,CS(C)=O,,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US20050245534A1,COC(=O)C1(N2CCN(c3ccc(C(F)(F)F)cn3)CC2)CC1>>O=C(O)C1(N2CCN(c3ccc(C(F)(F)F)cn3)CC2)CC1,,C1CCOC1,CO,[Na+].[OH-],,test
US20100184809A1,CC(C)c1nnn(-c2c(Cl)cccc2Cl)c1CO.Cc1nc(O)ccc1[N+](=O)[O-]>>Cc1nc(OCc2c(C(C)C)nnn2-c2c(Cl)cccc2Cl)ccc1[N+](=O)[O-],,c1ccccc1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040034034A1,CC(C)(C)OC(=O)CBr.NC(=O)C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1O>>CC(C)(C)OC(=O)COc1cc(Cl)ccc1OCC(=O)N1CCN(Cc2ccc(F)cc2)C[C@H]1CC(N)=O,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04004912,CN(CCC=O)C(=O)Nc1nnc(C2CCCCCC2)s1>>CN1CCC(O)N(c2nnc(C3CCCCCC3)s2)C1=O,,O,,Cl,,test
US20160096839A1,C=CC[C@H](NC(=O)OC(C)(C)C)c1cccc(-c2nc(C)ccc2NC(=O)[C@H](C)C=C)c1>>Cc1ccc2c(n1)-c1cccc(c1)[C@@H](NC(=O)OC(C)(C)C)CC=C[C@@H](C)C(=O)N2,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,ClCCCl,,,,test
US20150239837A1,CC(=O)c1c[nH]c2ccccc12.CC(C)(C)OC(=O)CBr>>CC(=O)c1cn(CC(=O)OC(C)(C)C)c2ccccc12,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US03968126,C1COC2(C1)CCCO2.[Fe+2].c1cc[cH-]c1.c1cc[cH-]c1>>OCCCC1([c-]2cccc2)CCCO1.[Fe+2].c1cc[cH-]c1,,ClCCl,,CCOCC,FB(F)F,test
US20100056508A1,NC1CCCCCC1.O=CCN(CCc1ccc(O)c2[nH]c(=O)ccc12)C(=O)OCc1ccccc1>>O=C(OCc1ccccc1)N(CCNC1CCCCCC1)CCc1ccc(O)c2[nH]c(=O)ccc12,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20150057273A1,Fc1ccc2nncn2c1.O=C1CCC(=O)N1Br>>Fc1ccc2nnc(Br)n2c1,,ClCCl,,,,test
US20130245021A1,CC(C)(C)OC(=O)N1CCCNCC1.Fc1ccc2ncc(Br)n2n1>>CC(C)(C)OC(=O)N1CCCN(c2ccc3ncc(Br)n3n2)CC1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US05679696,CSc1ccc(C(=O)Cl)cc1OC1CCCC1.Nc1c(Cl)cncc1Cl>>CSc1ccc(C(=O)Nc2c(Cl)cncc2Cl)cc1OC1CCCC1,,CN(C)C=O,,[H-].[Na+],,test
US20080027041A1,COCBr.O=c1[nH]ncc(Cl)c1Cl>>COCn1ncc(Cl)c(Cl)c1=O,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20010021718A1,CC(C)(C)OC(=O)C[C@@H](CCCC1CCCCC1)c1nc(CO)no1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCc2noc([C@H](CCCC3CCCCC3)CC(=O)OC(C)(C)C)n2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20160184307A1,COC(=O)c1cc(F)c(CNc2ccnc(Nc3cnn(C)c3)n2)c(F)c1>>Cn1cc(Nc2nccc(NCc3c(F)cc(C(=O)O)cc3F)n2)cn1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20160222030A1,Cc1noc(-c2ccccc2C(=O)N[C@H]2CCC[C@@H]2N)n1.Fc1ccc2nc(Cl)oc2c1>>Cc1noc(-c2ccccc2C(=O)N[C@H]2CCC[C@@H]2Nc2nc3ccc(F)cc3o2)n1,,CS(C)=O,,CCN(C(C)C)C(C)C,Cl,test
US20040133008A1,Cc1ccc(C2=C(C(=O)Nc3ccc(N(CCn4cccn4)C(=O)OC(C)(C)C)cc3)CCCC2)cc1>>Cc1ccc(C2=C(C(=O)Nc3ccc(NCCn4cccn4)cc3)CCCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110009438A1,CCSC(SCC)C(=O)NCc1ccc(C2=NOC(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1Cl.O=C(OO)c1cccc(Cl)c1>>CCSC(C(=O)NCc1ccc(C2=NOC(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1Cl)S(=O)CC,,ClCCl,,O=S([O-])O.[Na+],,test
US20100260710A1,COC(=O)C1CC(Oc2cc(-c3nc(C(F)(F)F)cs3)nc3c(C)c(OC)ccc23)CCN1C(=O)OCc1ccccc1>>COC(=O)C1CC(Oc2cc(-c3nc(C(F)(F)F)cs3)nc3c(C)c(OC)ccc23)CCN1,,O=C(O)C(F)(F)F,,O,,test
US06521643B1,CCOP(=O)(CC#N)OCC.COc1ccnc(-c2ccc(C=O)c([N+](=O)[O-])c2)c1>>COc1ccnc(-c2ccc(C=CC#N)c([N+](=O)[O-])c2)c1,,C1CCOC1,,O,[H-].[Na+],test
US20160072082A1,CC(C)[Si](Oc1ccc(NC(=O)OC(C)(C)C)cc1)(C(C)C)C(C)C>>CC(C)[Si](Oc1ccc(N)cc1)(C(C)C)C(C)C,,ClCCl,,O=C(O)C(F)(F)F,,test
US06136823,CN.Nc1cc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Cl)c32)ccc1F>>CNc1c(F)cc2c(=O)c(C(=O)O)cn(-c3ccc(F)c(N)c3)c2c1Cl,,c1ccncc1,,,,test
US06353117B1,Cc1ccc(/C=C/C(=O)C(F)(F)F)cc1.NNc1ccc(S(N)(=O)=O)cc1>>Cc1ccc(C2CC(C(F)(F)F)=NN2c2ccc(S(N)(=O)=O)cc2)cc1,,CC(=O)O,,O,,test
US20110213003A1,CO.COC(=O)c1cc(C=O)n(C)c1>>Cc1c(C(=O)O)cc(C=O)n1C,,O,,[Na+].[OH-],,test
US20090275578A1,COC(=O)c1c(C)cc(Br)cc1C.NC(=O)CCC(=O)NBr>>COC(=O)c1c(C)cc(Br)cc1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20030166929A1,CCOC(=O)C(C)C(C)=O.N#Cc1c(Cl)ccc([N+](=O)[O-])c1N>>CCOC(=O)C(C)(C(C)=O)c1ccc([N+](=O)[O-])c(N)c1C#N,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20110281862A1,COc1ccc(-c2ccc3[nH]c4ncc(-c5cccc(N)c5)cc4c3c2)cc1.O=S(=O)(Cl)c1ccccc1>>COc1ccc(-c2ccc3[nH]c4ncc(-c5cccc(NS(=O)(=O)c6ccccc6)c5)cc4c3c2)cc1,,c1ccncc1,,,,test
US05556864,COCOc1ccccc1CCl.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>COCOc1ccccc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Cl-],,Cc1ccccc1,,,,test
US20130017194A1,CCBr.NC(=O)Cc1cccnc1CCc1nc(Nc2ccc(C3CCCNC3)cc2)ncc1C(F)(F)F>>CCN1CCCC(c2ccc(Nc3ncc(C(F)(F)F)c(CCc4ncccc4CC(N)=O)n3)cc2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US07199124B2,Cc1cccc(C(=O)Cc2ccnc(NC(=O)OC(C)(C)C)c2)c1>>Cc1cccc(C(=O)Cc2ccnc(N)c2)c1,,Cl,,[Na+].[OH-],,test
US05747498,C#Cc1cccc(N)c1.O=[N+]([O-])c1ccc2c(Cl)ncnc2c1>>C#Cc1cccc(Nc2ncnc3cc([N+](=O)[O-])ccc23)c1.Cl,,CC(C)(C)O,,,,test
US03976786,CC(=O)Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1.CCI>>CCN(C(C)=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1,,CN(C)C=O,,O,[H-].[Na+],test
US20060178418A1,O=Cc1ccc(OC2CCCC2)c2oc3ccccc3c12>>O=Cc1ccc(O)c2oc3ccccc3c12,,Br,CC(=O)O,,,test
US20130184284A1,ClC(Cl)(Cl)C(Cl)(Cl)Cl.c1ccc(-c2cnco2)cc1>>Clc1ncc(-c2ccccc2)o1,,C1CCOC1,,[Li]CCCC,,test
US20120309738A1,N.N#Cc1c(F)ccc([N+](=O)[O-])c1F>>N#Cc1c(F)ccc([N+](=O)[O-])c1N,,C1CCOC1,,CCO,,test
US20130210796A1,C1CCNC1.C=O.C[Si](C)(C)N=[N+]=[N-].[C-]#[N+]c1ccc(C(F)(F)F)cc1>>FC(F)(F)c1ccc(-n2nnnc2CN2CCCC2)cc1,,CO,,,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(CC(O[Si](C)(C)C(C)(C)C)C2CCCCC2)c2nc(C)nn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(CC(O)C2CCCCC2)c2nc(C)nn12,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US20130172386A1,CC(C)(C)OC(=O)N1CC[C@@H](N=[N+]=[N-])[C@H](F)C1>>CC(C)(C)OC(=O)N1CC[C@@H](N)[C@H](F)C1,[Pd],CO,,O=C[O-].[NH4+],,test
US20150210682A1,CC[N+](=O)[O-].COc1ccc(C=O)cc1OCc1ccccc1>>COc1ccc(C=C(C)[N+](=O)[O-])cc1OCc1ccccc1,,Cc1ccccc1,,C,O=C[O-].[NH4+],test
US03952006,CCc1cc(C(=O)c2ccccc2Cl)c(-n2c(C)nnc2CO)s1.Cc1ccc(S(=O)(=O)Cl)cc1>>CCc1cc(C(=O)c2ccccc2Cl)c(-n2c(C)nnc2COS(=O)(=O)c2ccc(C)cc2)s1,,c1ccncc1,,,,test
US20090093507A1,CCOC(=O)CCCOc1cccc(CC(=O)OCc2ccccc2)c1>>COC(=O)CCCOc1cccc(CC(=O)O)c1,[Pd],CO,,,,test
US06166006,CI.COc1ccc(-c2cccc(C=CC(=O)Nc3ccc(CN4CCCCC4)cc3)c2)cc1>>COc1ccc(-c2cccc(C=CC(=O)Nc3ccc(C[N+]4(C)CCCCC4)cc3)c2)cc1.[I-],,CN(C)C=O,,,,test
US20140343032A1,CC(=O)OC1CC2CC(F)(F)C(C1)N2Cc1ccccc1>>OC1CC2CC(F)(F)C(C1)N2Cc1ccccc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04042707,C=CC=C.O=C1C=C(c2ccccc2)C(=O)O1>>O=C1OC(=O)C2(c3ccccc3)CC=CCC12,,Cc1ccccc1,,,,test
US05334716,CC(C)Cc1ccc(C(Cl)c2ccc(CC(C)C)cc2)cc1.CCOC(=O)CCCc1cc(C(=O)c2ccc(O)cc2)c2ccccn12>>CCOC(=O)CCCc1cc(C(=O)c2ccc(OC(c3ccc(CC(C)C)cc3)c3ccc(CC(C)C)cc3)cc2)c2ccccn12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150225412A1,CC(C)C=O.N#CCC(=O)N1CCC(n2c(NC(=O)c3cccnc3)nc3ccccc32)CC1>>CC(C)C=C(C#N)C(=O)N1CCC(n2c(NC(=O)c3cccnc3)nc3ccccc32)CC1,C1CCNCC1,CO,,,,test
US20080261941A1,CCOP(OCC)OCC.Cc1ccnc(Oc2cccc(CCl)c2)c1>>CCOP(=O)(Cc1cccc(Oc2cc(C)ccn2)c1)OCC,,CCOC(C)=O,,O,,test
US20120114739A1,COC(=O)Cc1ccc(Oc2cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n3ncc(-c4cnc5ccccc5c4)c3n2)cc1.O=C1CCC(=O)N1Br>>COC(=O)Cc1ccc(Oc2nc3c(-c4cnc5ccccc5c4)cnn3c(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)c2Br)cc1,,CC#N,,,,test
US20100130446A1,C=C[Mg]Br.CON(C)C(=O)C(CC1CCOCC1)c1ccc(SC)cn1>>C=CC(=O)C(CC1CCOCC1)c1ccc(SC)cn1,,C1CCOC1,,Cl,,test
US20080171741A1,CC(C)Br.Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc2cc[nH]c2c1>>Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc2ccn(C(C)C)c2c1,,CN(C)C=O,,[H-].[Na+],,test
US07342032B2,CCOC(=O)c1nc(-c2ccc(Cl)cc2Cl)c(-c2ccc(Br)cc2)s1.NN1CCCCC1>>O=C(NN1CCCCC1)c1nc(-c2ccc(Cl)cc2Cl)c(-c2ccc(Br)cc2)s1,,ClCCl,,,,test
US20060058303A1,CC(C)(O)c1cnn2c(Br)cnc2n1.CC1(C)COB(c2ccc(=O)n(-c3ncccc3C#N)c2)OC1>>CC(C)(O)c1cnn2c(-c3ccc(=O)n(-c4ncccc4C#N)c3)cnc2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20130102776A1,COc1ccc2c(c1CN1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccc(Cl)cc13)C2=O>>COc1ccc2c(c1CN1CCNCC1)O/C(=C\c1n[nH]c3ccc(Cl)cc13)C2=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020111492A1,CCOC(=O)C1(CCCc2c(F)cnc3ccc(OC)cc23)CCN(CCO)CC1.ClCCl.O=S(Cl)Cl>>CCOC(=O)C1(CCCc2c(F)cnc3ccc(OC)cc23)CCN(CCCl)CC1.Cl.Cl,,ClCCl,,,,test
US20080146561A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCC(CC)n1c(O)nc2ncc(Br)nc21>>CCC(CC)n1c(=O)n(C(=O)OC(C)(C)C)c2ncc(Br)nc21,,ClCCl,,CCN(CC)CC,,test
US20050203296A1,S=C1Nc2ccccc2Nc2sc(C3CCCC3)nc21.c1ccc(C[C@H]2CNCCN2)cc1>>c1ccc(C[C@H]2CN(C3=Nc4ccccc4Nc4sc(C5CCCC5)nc43)CCN2)cc1,,c1ccncc1,,,,test
US04894386,COC(=O)c1ccc2ccn(S(=O)(=O)c3ccc(C)cc3)c2c1>>Cc1ccc(S(=O)(=O)n2ccc3ccc(CO)cc32)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140107094A1,CC1(C)OC(=O)C(Cc2ccc(-n3cncn3)cc2)C(=O)O1>>O=C(O)C(Cc1ccc(-n2cncn2)cc1)C(=O)O,,O,O=C(O)C(F)(F)F,,,test
US20150322043A1,CCOC(=O)/C([O-])=C/C#N.NNc1cccc(OCc2ccccc2)c1>>CCOC(=O)c1cc(N)n(-c2cccc(OCc3ccccc3)c2)n1,,CCO,,Cl,,test
US20020120146A1,BrBr.CCc1cn2ccccc2n1>>CCc1nc2ccccn2c1Br,,CCO,O,,,test
US20130331378A1,COC(=O)c1cccc(Cc2c(-c3ccccc3)nn3cc(C4CC4)ccc23)n1>>O=C(O)c1cccc(Cc2c(-c3ccccc3)nn3cc(C4CC4)ccc23)n1,,CO,,Cl,[K+].[OH-],test
US20080287457A1,[O-][n+]1ccc2cc(-c3ccccc3)c(-c3ccc(CO)cc3)nc2c1>>O=c1[nH]ccc2cc(-c3ccccc3)c(-c3ccc(CO)cc3)nc12,,CC(=O)OC(C)=O,,O,[Na+].[OH-],test
US20110201777A1,Cn1c2ccc(-c3scc4c3[nH]c(=O)n4C(=O)OC(C)(C)C)cc2c2cc(-c3scc4c3[nH]c(=O)n4C(=O)OC(C)(C)C)ccc21>>Cn1c2ccc(-c3scc4[nH]c(=O)[nH]c34)cc2c2cc(-c3scc4[nH]c(=O)[nH]c34)ccc21,,CCOC(C)=O,,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],test
US20090227619A1,CCOC(=O)c1cc2c3ccccc3n(Cc3ccccc3)c2cn1>>OCc1cc2c3ccccc3n(Cc3ccccc3)c2cn1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20120232283A1,COc1ccccc1CN.O=C(Cl)c1ccccc1>>COc1ccccc1CNC(=O)c1ccccc1,,C1CCOC1,,CCN(CC)CC,,test
US20140057894A1,CC(C)CCN(CCC(C)C)C(=O)c1ccn2nc(Br)c(C(=O)O)c2c1>>CC(C)CCN(CCC(C)C)C(=O)c1ccn2nc(Br)cc2c1,,c1ccc(Oc2ccccc2)cc1,,,,test
US06310074B1,BrC(Br)(Br)Br.CC(=O)NCCc1c[nH]c2ccc(OCCCCO)cc12>>CC(=O)NCCc1c[nH]c2ccc(OCCCCBr)cc12,,CC#N,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100056377A1,Clc1ccc2nc(Cl)nc(-c3ccccc3)c2c1.OCCS>>OCCSc1nc(-c2ccccc2)c2cc(Cl)ccc2n1,,CN(C)C=O,,O,[H-].[Na+],test
US20140171432A1,CC(C)(C)[Si](C)(C)Cl.CC(O)CBr.Fc1ccc2[nH]nc(I)c2c1>>CC(Cn1nc(I)c2cc(F)ccc21)O[Si](C)(C)C(C)(C)C,CN(C)c1ccncc1,ClCCl,,,,test
US20110275611A1,Clc1cccc(-c2c[nH]c(C3CN(Cc4ccccc4)CCO3)n2)c1>>Clc1cccc(-c2c[nH]c(C3CNCCO3)n2)c1,[Pd],CO,,Cl,,test
US07071175B1,CC(C)CC=C(CC1CCN(C(=O)OC(C)(C)C)CC1)C(=O)OC(C)(C)C.COc1ccc(CS)cc1>>COc1ccc(CSC(CC(C)C)C(CC2CCN(C(=O)OC(C)(C)C)CC2)C(=O)OC(C)(C)C)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150175601A1,Nc1nc(Cl)nc2c(Br)cccc12>>Clc1ncc2cccc(Br)c2n1,,C1CCOC1,,CC(C)CCON=O,,test
US20080306087A1,Clc1ccc(C(c2ccc(Cl)cc2)N2CCNCC2)cc1.O=C(Cl)c1ccccc1F>>O=C(c1ccccc1F)N1CCN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CC1,CN(C)c1ccncc1,ClCCCl,,CCN(CC)CC,,test
US20090221555A1,CC(C)[C@@H](N)C(N)=O.Clc1ncc(Cl)c(Cl)n1>>CC(C)[C@@H](Nc1nc(Cl)ncc1Cl)C(N)=O,,CN(C)C=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20140274930A1,CNC(=O)c1cccc(-c2ccc(O[C@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@]3(CO)OC(C)=O)c(C)c2)c1>>CNC(=O)c1cccc(-c2ccc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@]3(O)CO)c(C)c2)c1,,CO,,C[O-].[Na+],,test
US04071625,CC(S)S.C[C@]12CC[C@H]3[C@@H](CC[C@H]4CC(=O)CC[C@@]43CO)[C@@H]1CC[C@]2(C)O>>C[C@]12CC[C@H]3[C@@H](CC[C@H]4CC5(CC[C@@]43CO)OCCS5)[C@@H]1CC[C@]2(C)O,,CC(=O)O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20160030395A1,Cc1noc(C)c1-c1ccc2c(c1)C(Cl)(c1ccccc1)C(=O)N2.OCCO>>Cc1noc(C)c1-c1ccc2c(c1)C(OCCO)(c1ccccc1)C(=O)N2,,C1CCOC1,O,c1ccncc1,,test
US20110028492A1,NCC1CCCCC1.N[C@@H]1CC[C@@H](Nc2ncc(Cl)c(-c3cccc(F)n3)n2)CC1>>N[C@@H]1CC[C@@H](Nc2ncc(Cl)c(-c3cccc(NCC4CCCCC4)n3)n2)CC1,,CS(C)=O,,,,test
US04941909,CN(C)C=O.Cn1c(C(F)(F)F)cc(=O)n(-c2cc(C(=O)O)c(Cl)cc2F)c1=O.O=S(Cl)Cl.c1ccccc1>>Cn1c(C(F)(F)F)cc(=O)n(-c2cc(C(=O)OC3CSC3)c(Cl)cc2F)c1=O,CN(C)C=O,,,,,test
US20050148627A1,CCOC(=O)C1=Cc2cc(Cl)c(F)cc2OC1C(F)(F)F.CCS>>CCOC(=O)C1=Cc2cc(Cl)c(SCC)cc2OC1C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04317823,Cc1nn(C)c2c1Nc1ccccc1NC2=O.O=C(Cl)CCl>>Cc1nn(C)c2c1N(C(=O)CCl)c1ccccc1NC2=O,,C1COCCO1,,CCN(CC)CC,,test
US20130252969A1,CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2[C@H](O)CO[C@H]12>>CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2C(=O)CO[C@H]12,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04722929,COc1cc(C(N)=O)ccc1-c1nc2[nH]c(=O)[nH]c(=O)c2[nH]1>>COc1cc(C#N)ccc1-c1nc2[nH]c(=O)[nH]c(=O)c2[nH]1,,O=P(Cl)(Cl)Cl,,,,test
US20090264437A1,CC(C)(C)c1nc(C2CCC2)cc(N2CCN(CCCOc3nccc(OCc4ccccc4)n3)CC2)n1>>CC(C)(C)c1nc(C2CCC2)cc(N2CCN(CCCOc3nccc(O)n3)CC2)n1,[Pd],C1CCOC1,,,,test
US20080171772A1,CN(C)C=O.COc1ccc2cc(C(C)C)n(Cc3ccccc3)c2c1>>COc1ccc2c(C=O)c(C(C)C)n(Cc3ccccc3)c2c1,,CCOC(C)=O,,O=P(Cl)(Cl)Cl,,test
US20060217372A1,COc1cc(C2OCCO2)ccc1O.N#Cc1cnc(Cl)cn1>>Cc1cc(C2OCCO2)ccc1Oc1cnc(C#N)cn1,,CN(C)C=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20140315917A1,O=C(NCCCl)NC1CCCC1>>O=C1NCCN1C1CCCC1,,C1CCOC1,,[H-].[Na+],,test
US20130178460A1,CC(C)(C)OC(=O)N[C@H]1COCC[C@H]1N.O=C(Nc1ccc2ccccc2c1)c1csc2cnc(Cl)nc12>>CC(C)(C)OC(=O)N[C@H]1COCC[C@H]1Nc1ncc2scc(C(=O)Nc3ccc4ccccc4c3)c2n1,,C1COCCO1,ClCCl,CCN(C(C)C)C(C)C,,test
US20070088044A1,CN1CCC(Oc2cccc3ncnc(Cl)c23)CC1.Cc1nsc2ccc(N)cc12>>Cc1nsc2ccc(Nc3ncnc4cccc(OC5CCN(C)CC5)c34)cc12.Cl,,CC(C)O,,,,test
US20100075976A1,CNCCN1CCN(c2nccnc2-c2ccc(COC)cc2)CC1.O=S(=O)(Cl)c1ccc(F)cc1>>COCc1ccc(-c2nccnc2N2CCN(CCN(C)S(=O)(=O)c3ccc(F)cc3)CC2)cc1.Cl,,ClCCl,,C1COCCN1,,test
US04289903,CN=C=O.Nc1ccc(O)c(Cl)c1>>CNC(=O)Nc1ccc(O)c(Cl)c1,,CCOC(C)=O,,,,test
US20050113400A1,CC(C)COc1ccccc1C=O.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)/C=C/c1ccccc1OCC(C)C,,C1CCOC1,O,CCOC(C)=O,[H-].[Na+],test
US04757080,C/C(N)=C/C(=O)OCCN1C(=O)c2ccccc2C1=O.COC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(C)=O>>COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN2C(=O)c3ccccc3C2=O)C1c1cccc([N+](=O)[O-])c1,,CCO,,,,test
US20110274638A1,COC(=O)/C(=C\c1ccc(OC)cc1OCc1ccccc1)NC(=O)OC(C)(C)C>>COC(=O)C(Cc1ccc(OC)cc1O)NC(=O)OC(C)(C)C,[Pd],CO,,,,test
US20050130982A1,C=O.CC(C)c1cccc(=O)c(O)c1.c1csc(N2CCNCC2)n1>>CC(C)c1ccc(CN2CCN(c3nccs3)CC2)c(=O)c(O)c1,,CO,,CC(=O)O,,test
US20150376130A1,N#Cc1ccc(C(F)(F)F)nc1Cl.NC1CC1>>N#Cc1ccc(C(F)(F)F)nc1NC1CC1,,CCOC(C)=O,,CCO,,test
US20110172237A1,Cc1ccc(N)nn1.O=C(Br)CBr>>Cc1ccc(NC(=O)CBr)nn1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20150295244A1,COS(=O)(=O)C(F)(F)F.O=C1C=CC(=O)c2nccnc21>>C[n+]1ccnc2c1C(=O)C=CC2=O.O=S(=O)([O-])C(F)(F)F,,Cc1ccccc1,,,,test
US20030134859A1,Cc1cccc(C(C)C)c1N.O=C(Cl)c1cc([N+](=O)[O-])ccc1Cl>>Cc1cccc(C(C)C)c1NC(=O)c1cc([N+](=O)[O-])ccc1Cl,,CC(=O)N(C)C,,,,test
US20090221653A1,CCOC(=O)COCCCO.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOC(=O)COCCCOS(=O)(=O)c1ccc(C)cc1,,ClCCl,,CCN(CC)CC,,test
US04407765,CC(=O)Cl.ClCCOP(OCCCl)OCCCl>>CC(=O)OP(OCCCl)OCCCl,,ClCCCl,,,,test
US06147098,N#CN=C(Oc1ccccc1)Oc1ccccc1.Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>N#CN=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Oc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US09085570B2,Cc1oc(-c2ccc(C(=O)O)cc2)nc1CO.NCc1cccnc1>>Cc1oc(-c2ccc(C(=O)NCc3cccnc3)cc2)nc1CO,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150087825A1,CC1(c2cc(Br)ccc2F)CC2(CCCCC2)SC(NC(=O)c2ccccc2)=N1>>CC1(c2cc(Br)ccc2F)CC2(CCCCC2)SC(N)=N1,,ClCCl,,NN,,test
US20150259286A1,N#Cc1ccc(OCc2ccccc2)c(N)c1.O=N[O-]>>N#Cc1ccc(OCc2ccccc2)c(NN)c1,,Cl,O,Cl[Sn]Cl,,test
US20140045872A1,COc1cccc(C=O)c1.C[N+](=O)[O-]>>COc1cccc(C=C[N+](=O)[O-])c1,,CCO,,[Na+].[OH-],,test
US20130225524A1,CCOC(=O)c1cccc(Nc2c(C(=O)NC3CCCC3O)cnc3cc(-c4c(C)noc4C)ccc23)c1>>Cc1noc(C)c1-c1ccc2c(Nc3cccc(C(=O)O)c3)c(C(=O)NC3CCCC3O)cnc2c1,,CCO,,[Na+].[OH-],,test
US20110082133A1,COC(=O)c1ccc(CCn2c(CBr)c(Cl)cc(Cl)c2=O)cc1.c1ccc(Nc2ccccc2)cc1>>COC(=O)c1ccc(CCn2c(CN(c3ccccc3)c3ccccc3)c(Cl)cc(Cl)c2=O)cc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],[Cl-].[NH4+],test
US20020114759A1,O=S(=O)([O-])[O-].[Cl-].[NH4+].[Na+].[Na+]>>Cl.O=S(=O)([O-])[O-].[NH4+].[Na+].[Na+],,O,,[Cl-].[Na+],,test
US20160046596A1,Cc1cc(-c2nccc(C=O)c2O)ccn1.Nc1ccc(F)c(Cl)c1>>Cc1cc(-c2nccc(C=Nc3ccc(F)c(Cl)c3)c2O)ccn1,,CC#N,,,,test
US20110034689A1,Cc1cc([N+](=O)[O-])ccc1Oc1ccnc(NC(=O)OC(C)(C)C)c1>>Cc1cc([N+](=O)[O-])ccc1Oc1ccnc(N)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04767776,CO.COc1ccc2ccc(C(=O)O)c(O)c2c1>>COC(=O)c1ccc2ccc(OC)cc2c1O,,CO,,CCOCC,FB(F)F,test
US20090298825A1,CC(C(=O)O)c1ccc(Cl)c(C(F)(F)F)c1.Cc1cc(-n2ccc3c(N)cccc3c2=O)n[nH]1>>Cc1cc(-n2ccc3c(NC(=O)C(C)c4ccc(Cl)c(C(F)(F)F)c4)cccc3c2=O)n[nH]1,,O=S(Cl)Cl,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20040116697A1,COC(=O)CCc1c(Nc2c(F)cccc2F)nc(SC)nc1-c1ccc(F)cc1C>>CSc1nc(-c2ccc(F)cc2C)c2c(n1)N(c1c(F)cccc1F)C(=O)CC2,,CO,,C[O-].[Na+],,test
US05597918,CC(=O)c1cc2c(s1)CCc1cc(=O)n(-c3ccc(C)cc3)nc1-2>>Cc1ccc(-n2nc3c(cc2=O)CCc2sc(C(C)O)cc2-3)cc1,,CO,,[BH4-].[Na+],,test
US20090137607A1,CN.Clc1nc2nccn2c(Cl)c1-c1ccccc1>>CNc1c(-c2ccccc2)c(Cl)nc2nccn12,,CO,,,,test
US20080188521A1,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.Cc1ccc(C(=O)c2cc(C)on2)c(O)c1>>Cc1ccc2c(-c3cc(C)on3)cc(=O)oc2c1,,Cc1ccccc1,,,,test
US05753665,CC(=O)C(C)Oc1ccc(Cl)cc1.COC(OC)N(C)C>>CC(Oc1ccc(Cl)cc1)C(=O)C=CN(C)C,,CO,,,,test
US05300524,OCCCCCc1cccnc1.OCCCc1cccnc1>>O=CCCCCc1cccnc1,,CO,ClC(Cl)Cl,,,test
US20040186103A1,C[C@@H](C(=O)O)c1ccc(F)cc1.Cc1ccc(NC(=O)C(C)C)cc1C1CCN(CCCN)CC1>>Cc1ccc(NC(=O)C(C)C)cc1C1CCN(CCCNC(=O)[C@H](C)c2ccc(F)cc2)CC1,,CO,,,,test
US20080009482A1,CC(C)(CN)CN1CCCC1.COc1cc(C(=O)O)ccc1N>>COc1cc(C(=O)NCC(C)(C)CN2CCCC2)ccc1N,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080139558A1,CCO.O=c1cc(CNc2cccc(Cl)c2)c2cccc(F)c2[nH]1>>CCN(Cc1cc(=O)[nH]c2c(F)cccc12)c1cccc(Cl)c1,,CC(=O)O,CCO,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04031093,CCCOc1ccccc1C(N)=O.CC[O+](CC)CC.F[B-](F)(F)F>>CCCOc1ccccc1C(=N)OCC.F[B-](F)(F)F,,ClCCl,,,,test
US20120196869A1,CC(=O)Cl.COc1cc(C(=O)N2CCC3(CC2)NCCn2c(C(F)(F)F)ccc23)ccc1OC(C)C>>COc1cc(C(=O)N2CCC3(CC2)c2ccc(C(F)(F)F)n2CCN3C(C)=O)ccc1OC(C)C,,c1ccncc1,,,,test
US20150152131A1,CC(C)[Si](OCCCC(O)COCc1ccccc1)(C(C)C)C(C)C.CS(=O)(=O)Cl>>CC(C)[Si](OCCCC(COCc1ccccc1)OS(C)(=O)=O)(C(C)C)C(C)C,,CCOC(C)=O,,CCN(CC)CC,Cl,test
US20090076147A1,CCOC(=O)OCCOC(=O)[C@H](O)C(C)(C)COS(=O)(=O)CCCNC(C)=O.O=P(Cl)(Oc1ccccc1)Oc1ccccc1>>CCOC(=O)OCCOC(=O)[C@H]([PH](=O)Oc1ccccc1)C(C)(C)COS(=O)(=O)CCCNC(C)=O,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US05292732,CC(=O)NCCN.COc1ccc2c(c1)C(=O)C(CC=O)CC2>>COc1ccc2c(c1)-c1c(ccn1CCNC(C)=O)CC2,,ClCCl,,,,test
US20150299192A1,CC(=O)Cl.O=[N+]([O-])c1ccc(CN2CCN(CCO)CC2)c(C(F)(F)F)c1>>CC(=O)OCCN1CCN(Cc2ccc([N+](=O)[O-])cc2C(F)(F)F)CC1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US05834463,O=C1Nc2ccccc2N=C2CCCC12.O=[N+]([O-])c1ccc(CBr)cc1>>O=C1C2CCCC2=Nc2ccccc2N1Cc1ccc([N+](=O)[O-])cc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US04093812,COC(=O)n1cc(C=O)c(-c2ccc([N+](=O)[O-])o2)n1.NN1CCOCC1>>COC(=O)n1cc(C=NN2CCOCC2)c(-c2ccc([N+](=O)[O-])o2)n1,,CO,,CC(=O)O,,test
US20080146565A1,CSc1nccc(C=O)n1.NNc1ccccn1>>CSc1nccc(/C=N/Nc2ccccn2)n1,,CCO,,,,test
US20060257987A1,CCc1ccc(O[C@@H](C)CCOc2ccc(C(C)C(=O)OC)c(C)c2)c(-c2ccc[nH]2)c1>>CCc1ccc(O[C@@H](C)CCOc2ccc(C(C)C(=O)O)c(C)c2)c(-c2ccc[nH]2)c1,,CO,,,,test
US06057451,CCCCNCCCC.Nc1nc(-c2ccc(CCNC(=O)Oc3ccccc3)cc2)cs1>>CCCCN(CCCC)C(=O)NCCc1ccc(-c2csc(N)n2)cc1,,CS(C)=O,,,,test
US20050026964A1,CCOC(=O)c1cnc(Cl)cc1Cl.Nc1ccc(I)cc1F>>CCOC(=O)c1cnc(Cl)cc1Nc1ccc(I)cc1F,Cl,CCO,,,,test
US20140371278A1,COC(=O)c1cc(SCc2ccc(OC)cc2)c(F)c(F)c1Nc1ccccc1F.[N-]=[N+]=[N-]>>COC(=O)c1cc(SCc2ccc(OC)cc2)c(N=[N+]=[N-])c(F)c1Nc1ccccc1F,,CN(C)C=O,,O,,test
US20020035136A1,COc1cc(-c2cccc3ccccc23)ccc1CNCc1ccccc1>>Oc1cc(-c2cccc3ccccc23)ccc1CNCc1ccccc1,,ClCCl,,BrB(Br)Br,,test
US20090176823A1,CC(C)(C)[SiH2]OC(C)(C)c1cc(CN)ccc1Cl.CCC(=O)Cl>>CCC(=O)NCc1ccc(Cl)c(C(C)(C)O[SiH2]C(C)(C)C)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20130059883A1,O=C1CSC(=S)N1.O=Cc1cc(-c2ccccc2)cs1>>O=C1NC(=S)SC1=Cc1cc(-c2ccccc2)cs1,,CC(=O)O,,O,CC(=O)[O-].[Na+],test
US06169107A,COC(=O)c1cc2ccccc2n1CCOC1CCCCO1.N=C(N)N>>NC(=NC(=O)c1cc2ccccc2[nH]1)NCCOC1CCCCO1,,CO,,Cl,C[O-].[Na+],test
US05216018,C1CCC2CNCCC2C1.O=C(Cl)Cc1ccccc1>>O=C(Cc1ccccc1)C1NCCC2CCCCC21,,ClCCl,,[Na+].[OH-],,test
US04472406,CCOC(CNC(=S)Nc1cccc2nc(C)ccc12)OCC>>Cc1ccc2c(-n3ccnc3S)cccc2n1,,Cl,,[NH4+].[OH-],,test
US03952031,CC(=O)OC(C)=O.CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(C)=O)[C@@]4(C)CC(=O)[C@@H]32)C[C@@H]1O>>CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(C)=O)[C@@]4(C)CC(=O)[C@@H]32)C[C@@H]1OC(C)=O,,ClCCl,,c1ccncc1,,test
US04339453,Clc1ccnc(Cl)n1.NCCCO>>OCCCNc1ccnc(Cl)n1,,O,,CCCCO,,test
US20040147739A1,CCOC(=O)CC(=O)Cl.Nc1ccc(Br)cc1S(N)(=O)=O>>COC(=O)CC1=Nc2ccc(Br)cc2S(=O)(=O)N1,,C1CCOC1,,CCN(CC)CC,CN(C)c1ccccn1,test
US05512575,O=C(OCc1ccccc1)N1CCC(O)CC1>>O=C1CCN(C(=O)OCc2ccccc2)CC1,,ClCCl,,CCN(CC)CC,CS(C)=O,test
US20110135670A1,CCCCOc1nc(N)c2nc(OC)n(CCCNCC3CCOC3)c2n1>>CCCCOc1nc(N)c2[nH]c(=O)n(CCCNCC3CCOC3)c2n1,,CO,,C1COCCO1,Cl,test
US20060106017A1,N#CC(=NO)c1ccccc1.O=C(Cl)c1ccccc1>>N#CC1(/C=N/OC(=O)c2ccccc2)C=CC=CC1,,ClCCl,,CCN(CC)CC,,test
US20030162799A1,COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C.Clc1nccc2cnccc12>>COC(=O)[C@H](Cc1ccc(Oc2nccc3cnccc23)cc1)NC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090105257A1,CC(C)N.Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CNc1ccc([C@@H]2C[C@H]2C(=O)O)cc1>>Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CNc1ccc([C@@H]2C[C@H]2C(=O)NC(C)C)cc1,,CN(C)C=O,ClCCl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20130190487A1,Fc1ccc([Mg]Br)cc1.O=C(Cl)CC[C@H]1C(=O)N(c2ccc(F)cc2)[C@@H]1c1ccc(OCc2ccc(Br)cc2)cc1>>O=C(CC[C@H]1C(=O)N(c2ccc(F)cc2)[C@@H]1c1ccc(OCc2ccccc2)cc1)c1ccc(F)cc1,,C1CCOC1,,,,test
US20090275537A1,COC(=O)CC[C@@H](COC(=O)Nc1cc2cc(F)ccc2cn1)N(C)C(=O)NCc1cccc(F)c1Cl>>CN(C(=O)NCc1cccc(F)c1Cl)[C@@H](CCC(=O)O)COC(=O)Nc1cc2cc(F)ccc2cn1,,C1COCCO1,CCOC(C)=O,Cl,[Li+].[OH-],test
US20150005279A1,Cc1ccc(S(=O)(=O)n2ccc3c(C4CO4)ccc(C#N)c32)cc1.NCCO>>Cc1ccc(S(=O)(=O)n2ccc3c(C(O)CNCCO)ccc(C#N)c32)cc1,,CC(C)O,,,,test
US20030119842A1,CC(=O)Cl.Nc1ccc([N+](=O)[O-])cn1.O=Cc1ccccn1.[C-]#[N+]C1CCCCC1>>CC(=O)[n+]1c(-c2ccccn2)c(NC2CCCCC2)n2cc([N+](=O)[O-])ccc21.[Cl-],,[O-][Cl+3]([O-])([O-])O,,,,test
US20110057559A1,CC(C)c1cc(Br)cc(C(C)C)c1N.OB(O)c1ccccc1>>CC(C)c1cc(-c2ccccc2)cc(C(C)C)c1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,Cc1ccccc1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20120289501A1,CCOC(=O)C1CCc2ccc(OCc3ccccc3)cc2O1>>OCC1CCc2ccc(OCc3ccccc3)cc2O1,,C1CCOC1,,[BH4-].[Li+],,test
US20020173503A1,COc1ccc(-c2cc3c4c(c2)[C@@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2N4CCSC3)c(C)c1>>COc1ccc(-c2cc3c4c(c2)[C@@H]2CNCC[C@@H]2N4CCSC3)c(C)c1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US06174885B1,CCCCCCCCCCCCCCCCCCN(C=O)C1CC=CCC1COC(=O)NCCCN(C)C.Cl>>CCCCCCCCCCCCCCCCCCN(C=O)C1CC=CCC1COC(=O)NCCCN(C)C.Cl,,CCO,CCOC(C)=O,,,test
US20060094716A1,C1CCOC1.Cc1cc(N)c2ccccc2n1.O=C(n1ccnc1)n1ccnc1>>Cc1cc(NC(=O)Nc2cc(C)nc3ccccc23)c2ccccc2n1,,C1CCOC1,,,,test
US05352790,C=O.CCC1=C2c3[nH]c4ccccc4c3CCN2CCC1>>CCC1(CO)CCCN2CCC3=c4ccccc4=NC3=C21,,CC(C)=O,,O,,test
US04963557,C=CCC(C=O)CCC>>CCCC(C=O)CCC,[Pd],CCOC(C)=O,,[H][H],,test
US20130102611A1,c1ccc(-c2cc3cccnc3nc2-c2ccccc2)cc1>>c1ccc(-c2cc3c(nc2-c2ccccc2)NCCC3)cc1,[Pd],CCO,,N#N,,test
US20050203126A1,CC(=O)OC(C)=O.COc1cc(C(=O)c2c(C)c(N)c3ccccn23)ccc1[N+](=O)[O-]>>COc1cc(C(=O)c2c(C)c(NC(C)=O)c3ccccn23)ccc1[N+](=O)[O-],,ClCCl,,,,test
US05576334,CCOCCC(Cc1ccc(NC(=O)NC(=O)c2ccc(C#N)cc2)cc1)C(=O)OC(C)(C)C.S>>CCOCCC(Cc1ccc(NC(=O)NC(=O)c2ccc(C(N)=S)cc2)cc1)C(=O)OC(C)(C)C,,CCN(CC)CC,,c1ccncc1,,test
US20100063081A1,CCOC(=O)CC(=O)C1CCN(C(=O)OC(C)(C)C)CC1.CSc1ccc(CCBr)cc1>>CCOC(=O)C(CCc1ccc(SC)cc1)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1,,CCO,,[Na],,test
US06369070B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(N)c1cccc([N+](=O)[O-])c1>>CC(NC(=O)OC(C)(C)C)c1cccc([N+](=O)[O-])c1,,ClCCl,,,,test
US20050239776A1,CC(C)(C)[SiH2]OC(C)(C)c1onc(-c2ccccc2Cl)c1C(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-c1cnccn1>>O=C(c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-c1cnccn1)c1c(-c2ccccc2Cl)noc1CO,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100056577A1,CCOC(=O)C(F)(F)C(CNC(=O)OC(C)(C)C)OS(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)OC2CN(C(=O)OC(C)(C)C)C(=O)C2(F)F)cc1,,CCOC(C)=O,,Cl,,test
US05278175,CC(c1ncnc(Cl)c1Cl)C(O)(Cn1cncn1)c1ccc(F)cc1F>>CC(c1ncncc1Cl)C(O)(Cn1cncn1)c1ccc(F)cc1F,[Pd],CCO,,CC(=O)[O-].[Na+],,test
US20160264518A1,CCOC(=O)/C=C/c1ccccc1Br.O=C1NCCN1c1ccccc1>>CCOC(=O)/C=C/c1ccccc1N1CCN(c2ccccc2)C1=O,[Cu]I,CN(C)C=O,,CN[C@@H]1CCCC[C@H]1NC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US05041455,C=CCCCO.Clc1nsnc1-c1cccnc1>>C=CCCCOc1nsnc1-c1cccnc1,,C1CCOC1,,O,[H-].[Na+],test
US06498165B1,Cc1cc2nc[nH]c2cc1[N+](=O)[O-]>>Cc1cc2nc[nH]c2cc1N,[Pd],C1CCOC1,,,,test
US20100136142A1,CC(=O)CC(=O)OCCC#N.COc1cc(C#N)ccc1C=O.Nc1cc[nH]c(=O)c1>>COc1cc(C#N)ccc1C1C(C(=O)OCCC#N)=C(C)Nc2cc[nH]c(=O)c21,,CC(C)O,,,,test
US05286721,C=CCOC(=O)NCC(CO)C(C)O[Si](C)(C)C(C)(C)C.CS(=O)(=O)Cl>>C=CCOC(=O)NCC(COS(C)(=O)=O)C(C)O[Si](C)(C)C(C)(C)C,,ClCCl,,CCN(CC)CC,O,test
US20100087440A1,COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2cccc(N)c2)cc(OC)c1.O=C(O)CBr>>COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2cccc(NC(=O)CBr)c2)cc(OC)c1,,ClCCl,,CC(C)N=C=NC(C)C,,test
US05922733,CCOC(=O)c1csc2cc(OC)c(Br)cc12>>COc1cc2scc(C(=O)O)c2cc1Br,,CCO,O,[Na+].[OH-],,test
US05656626,C[Sn](C)(C)c1ccccc1.O=c1[nH]c2cc(Cl)ccc2c(=O)c(Br)c1O>>O=c1[nH]c2cc(Cl)ccc2c(=O)c(-c2ccccc2)c1O,,C1CCOC1,,,,test
US20150051199A1,CC[C@@H](NC(C)(C)CC(=O)O)c1ccc(Cl)c(C(=O)c2cccnc2)c1F.[NH4+]>>CC[C@@H](NC(C)(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2cccnc2)c1F,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030018067A1,CC(C)CC(=O)Cl.COc1ccc2cc(-c3cc4ccccc4o3)ccc2c1>>COc1ccc2cc(-c3oc4ccccc4c3C(=O)CC(C)C)ccc2c1,,ClC(Cl)Cl,,Cl[Sn](Cl)(Cl)Cl,,test
US20080171772A1,COc1ccc2c(C(=O)O)c(C(C)C)n(Cc3ccccc3)c2c1.NCc1ccc(F)c(F)c1>>COc1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3ccccc3)c2c1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,ClCCCl,,test
US20090137557A1,CCOC(=O)C(CC)C(C)=O.OCCO>>CCOC(=O)C(CC)C1(C)OCCO1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090298823A1,Cc1ccc(S(=O)(=O)n2cc(C#N)c3c(NC4CC4)nc(Cl)nc32)cc1.Nc1ccc2c(c1)CCC(=O)N2>>N#Cc1c[nH]c2nc(Nc3ccc4c(c3)CCC(=O)N4)nc(NC3CC3)c12,,CCCCO,,C[Si](C)(C)Cl,,test
US05104885,CC(Br)CCCN1C(=O)c2ccccc2C1=O.COc1cc(N)c2nccc(C)c2c1OCCCCCc1cccs1>>COc1cc(NC(C)CCCN2C(=O)c3ccccc3C2=O)c2nccc(C)c2c1OCCCCCc1cccs1,,CCN(CC)CC,,,,test
US03957761,O=C(c1ccccc1Cl)c1cc(C(F)(F)F)ccc1-n1c(CN2CCCCC2)nnc1CN1C(=O)c2ccccc2C1=O>>FC(F)(F)c1ccc2c(c1)C(c1ccccc1Cl)=NCc1nnc(CN3CCCCC3)n1-2,,CCO,,NN,O,test
US06447656B1,O=C(O)CCCCCCCCCCS.OC(c1ccccc1)c1ccccc1>>O=C(O)CCCCCCCCCCSC(c1ccccc1)c1ccccc1,,O=C(O)C(F)(F)F,,,,test
US04675335,OCCCCCCCCCCBr.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>OCCCCCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-],,CC#N,,,,test
US20100029740A1,CSCC1C2CNCC21c1ccc(Cl)c(Cl)c1.Cl>>CSCC1C2CNCC21c1ccc(Cl)c(Cl)c1.Cl,,CCOCC,ClCCl,,,test
US20100280071A1,CCOC(=O)N1CCC(Nc2cc(C(F)(F)F)ccc2[N+](=O)[O-])CC1>>CCOC(=O)N1CCC(Nc2cc(C(F)(F)F)ccc2N)CC1,[Pd],CO,,,,test
US20160024054A1,C[C@H](NC(=O)OC(C)(C)C)c1nc2cccc(/C=C/CC3CCCCC3)c2c(=O)n1-c1ccccc1>>C[C@H](NC(=O)OC(C)(C)C)c1nc2cccc(CCCC3CCCCC3)c2c(=O)n1-c1ccccc1,[Pd],CCOC(C)=O,,,,test
US20140371204A1,O=C(CN1CCc2[nH]ncc2C1)OCc1ccccc1>>O=C(O)CN1CCc2[nH]ncc2C1,,CCO,,,,test
US20150011751A1,CCOC(=O)c1ccc(N)cc1.Clc1ncnc(Cl)n1>>CCOC(=O)c1ccc(Nc2ncnc(Cl)n2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20130150371A1,CCOC(=O)C1CC1c1nc(-c2ccccc2)c[nH]1.CI>>CCOC(=O)C1CC1c1nc(-c2ccccc2)cn1C,,CCOCC,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100298324A1,COC(=O)c1cc([N+](=O)[O-])c(C(=O)OC)cc1OC>>COC(=O)c1cc(OC)c(C(=O)OC)cc1N,[Pd],CO,,,,test
US03962441,CC(=O)OC(C)=O.CCOC(=O)C(C)c1ccc(O)c(N)c1>>CCOC(=O)C(C)c1ccc(O)c(NC(C)=O)c1,,c1ccncc1,,O,,test
US20040236114A1,CCOC(=O)c1ncn([C@H](CO)[C@H](C)O)c1N>>CCOC(=O)c1cn([C@H](CO)[C@H](C)O)cn1,,C1CCOC1,,CC(C)CCON=O,,test
US20090181928A1,NCCc1ccc([N+](=O)[O-])c(OCc2ccccc2)c1.O=S(=O)(Cl)c1ccccc1>>CN(Cc1ccc([N+](=O)[O-])c(OCc2ccccc2)c1)S(=O)(=O)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US04988689,CN=C=O.NCCN1CCC(Nc2nc3ccccc3n2Cc2ccc(F)cc2)C1>>CNC(=O)NCCN1CCC(Nc2nc3ccccc3n2Cc2ccc(F)cc2)C1,,C1CCOC1,,[Ca+2].[Cl-].[Cl-],,test
US20120220778A1,CN1CCC(=O)CC1.CNS(=O)(=O)CCc1ccc2c(ccn2Cc2ccccc2)c1>>CNS(=O)(=O)CCc1ccc2c(c1)c(C1=CCN(C)CC1)cn2Cc1ccccc1,,CO,,O,[K+].[OH-],test
US20050137171A1,CC(=O)n1ncc2cc(O)ccc21.O=[N+]([O-])c1ccc(OP(=O)(Oc2ccc([N+](=O)[O-])cc2)c2ccccc2)cc1>>CC(=O)n1ncc2cc(OP(=O)(Oc3ccc([N+](=O)[O-])cc3)c3ccccc3)ccc21,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20130082209A1,COB(OC)OC.Cc1cc2c(nc3c4ccc(C(C)(C)C)nc4cc(C(C)(C)C)n23)c(Br)c1C>>Cc1cc2c(nc3c4ccc(C(C)(C)C)nc4cc(C(C)(C)C)n23)c(O)c1C,,C1CCOC1,,[Li]CCCC,,test
US05798316,COc1ccc(-n2c(=O)cc(C(F)(F)F)n(N)c2=O)cc1>>Nn1c(C(F)(F)F)cc(=O)n(-c2ccc(O)cc2)c1=O,,ClCCl,,BrB(Br)Br,,test
US20060063779A1,O=C(Nc1ccc(Cl)c(-c2ccccn2)c1)c1ccc(S(=O)(=O)CCCBr)cc1Cl>>C=CCS(=O)(=O)c1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)c(Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060128633A1,COC(=O)Cl.COc1cc2c(c(OC)c1OC)-c1ccc(O)cc1C(NC(C)=O)CC2>>COC(=O)Oc1ccc2c(c1)[C@@H](NC(C)=O)CCc1cc(OC)c(OC)c(OC)c1-2,,C1CCOC1,,CCN(CC)CC,,test
US20150031685A1,COC(=O)c1ccc(CS(=O)(=O)[O-])c([N+](=O)[O-])c1.[Na+]>>COC(=O)c1ccc(CS(=O)(=O)[O-])c(N)c1.[Na+],[Pd],CO,,[H][H],,test
US04112095,CCc1nnc2cc(C)c(-c3ccc(C#N)cc3)nn12.OO>>CCc1nnc2cc(C)c(-c3ccc(C(N)=O)cc3)nn12,,CCO,,[Na+].[OH-],,test
US20060135613A1,CC1=CCC(Cl)(C(=O)O)C=C1>>OCc1ccc(CCl)cc1,,C1CCOC1,,B,,test
US20070099990A1,Cc1c(NC(=O)CC(C)(C)C)cc2c(c1C)OC(C)(C)C2(O)c1ccc(Br)cc1>>Cc1c(NC(=O)CC(C)(C)C)cc2c(c1C)OC(C)(C)C2c1ccc(Br)cc1,,CCCCCC,CCOC(C)=O,,,test
US20150203486A1,CS(=O)(=O)Cl.Cn1nc(N)cc1Br>>Cn1nc(NS(C)(=O)=O)cc1Br,,ClCCCl,,CCN(C(C)C)C(C)C,,test
US04105772,CN.Cn1cc(C=CC(=O)Cl)c([N+](=O)[O-])n1>>CNC(=O)C=Cc1cn(C)nc1[N+](=O)[O-],,Cc1ccccc1,,,,test
US20100184740A1,Cc1cc([N+](=O)[O-])ccc1F.O=C1CCC(=O)N1Br>>O=[N+]([O-])c1ccc(F)c(CBr)c1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20060211694A1,C#Cc1ccccc1.O=c1c(Br)c(OS(=O)(=O)C(F)(F)F)ccn1Cc1cccc(F)c1>>O=c1c(Br)c(C#Cc2ccccc2)ccn1Cc1cccc(F)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,,,test
US05130482,CC(C)NC[C@H](O)COc1ccc(CC(N)=O)cc1.Cc1ccc(C(=O)O)cc1>>CC(C)NC[C@H](O)COc1ccc(CC(N)=O)cc1.Cc1ccccc1C(=O)[O-],,CC(C)=O,,,,test
US20030114666A1,O=C(NC(=O)c1cc(F)c(F)c(C(F)F)c1F)NC1CC1>>O=c1[nH]c(=O)n(C2CC2)c2c(C(F)F)c(F)c(F)cc12,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US07074819B2,COCOc1ccc(C2(C)COc3cc(OCOC)ccc3C2CCCCCCCCC/C(=C\CCC(F)(F)C(F)(F)F)C(=O)O)cc1>>CC1(c2ccc(O)cc2)COc2cc(O)ccc2C1CCCCCCCCC/C(=C\CCC(F)(F)C(F)(F)F)C(=O)O,Cl,CCO,O,,,test
US20100048636A1,CC(C)(C)OC(=O)N1[C@@H](C[C@H]2CC=CCOC2)COC1(C)C>>CC(C)(C)OC(=O)N1[C@@H](C[C@H]2CCCCOC2)COC1(C)C,[Ni],CCO,,,,test
US20140350002A1,CC1C(CN)C1c1ccc2c(n1)n(C)c(=O)n2CC(C)(C)C.O=C(O)c1ccon1>>CC1C(CNC(=O)c2ccon2)C1c1ccc2c(n1)n(C)c(=O)n2CC(C)(C)C,,CC#N,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090264450A1,CN(C)C(=O)Oc1cccc(NC(=O)C2(Cc3c[nH]cn3)CCNCC2)c1.CN(C)C(=O)Oc1cccc(NC(=O)C2(Cc3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)CCN(C(=O)OC(C)(C)C)CC2)c1>>Cc1c[nH]c2ncnc(N3CCC(Cc4c[nH]cn4)(C(=O)Nc4cccc(OC(=O)N(C)C)c4)CC3)c12,,CO,,Cl,,test
US20110237565A1,CC(C)(C)OC(=O)N1CCN(c2ncc(Br)n3nnnc23)CC1.OB(O)c1cccs1>>CC(C)(C)OC(=O)N1CCN(c2ncc(-c3cccs3)n3nnnc23)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US20030220495A1,COC(=O)c1ccc(/C=C(/Cn2ccnc2)c2nccs2)cc1-c1ccccc1>>COC(=O)c1ccc(CC(Cn2ccnc2)c2nccs2)cc1-c1ccccc1,[Pd],CO,,,,test
US20140057902A1,CC(=O)OC(C)=O.NCCc1ccccc1I>>CC(=O)NCCc1ccccc1I,,C1COCCO1,,,,test
US04720586,CCOC(=O)CCCCCBr.c1ccc(CNCCc2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)cc1>>CCOC(=O)CCCCCN(CCc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1)Cc1ccccc1,,CC#N,,[I-].[K+],,test
US20050004149A1,CNC.Nc1nc(-c2ccco2)c(-c2ccnc(F)c2)c(-c2ccco2)n1>>CN(C)c1cc(-c2c(-c3ccco3)nc(N)nc2-c2ccco2)ccn1,,COCCOC,,,,test
US20060100226A1,N#Cc1c(-c2c[nH]c3ccccc23)[nH]c(=S)[nH]c1=O.O=C(Nc1cccc(CBr)c1)c1ccc(Cl)c(Cl)c1>>N#Cc1c(-c2c[nH]c3ccccc23)nc(SCc2cccc(NC(=O)c3ccc(Cl)c(Cl)c3)c2)[nH]c1=O,,CCO,,CCN(C(C)C)C(C)C,,test
US04518685,CC(C(=O)O)C(=O)O.CNC(=O)NC>>CC1C(=O)N(C)C(=O)N(C)C1=O,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20110184188A1,Cc1nc(C)c([N+](=O)[O-])cc1F.O=C1CCC(=O)N1Br>>Cc1nc(CBr)c([N+](=O)[O-])cc1F,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20110257165A1,COc1cccc(-c2nn3c(c2-c2ccncc2)SCC3O)c1>>COc1cccc(-c2nn3ccsc3c2-c2ccncc2)c1,,CCOC(C)=O,COCCOC,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US20160002273A1,CC(C)(C)OC(=O)NCCC1CCNCC1.NC(=O)c1cc2ncnc(Cl)c2o1>>CC(C)(C)OC(=O)NCCC1CCN(c2ncnc3cc(C(N)=O)oc23)CC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US05470849,CC(C)(C)[Si](OCCC1=CC(CC(=O)OCc2ccccc2)C(=O)N(c2ccccc2)CC1)(c1ccccc1)c1ccccc1>>O=C(CC1C=C(CCO)CCN(c2ccccc2)C1=O)OCc1ccccc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150045368A1,CO.N[C@H](C(=O)O)c1ccc(F)cc1>>COC(=O)[C@@H](N)c1ccc(F)cc1,,CCOC(C)=O,,O=S(Cl)Cl,,test
US04122090,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.COC(=O)[C@@H](N)Cc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.COC(=O)[C@@H](N)Cc1ccccc1,,C1CCOC1,,CCN(CC)CC,Cl,test
US20160222030A1,CC(C)(C)OC(=O)N[C@@H]1COC[C@H]1N.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@@H]1COC[C@H]1NC(=O)OCc1ccccc1,,ClCCl,,,,test
US20060211730A1,Cc1cc(COc2ccc(S(=O)(=O)Cl)cc2)c2ccccc2n1.N[C@H]1CC=CC[C@H]1C(=O)O>>Cc1cc(COc2ccc(S(=O)(=O)N[C@H]3CC=CC[C@H]3C(=O)O)cc2)c2ccccc2n1,,C1COCCO1,O,CCN(CC)CC,Cl,test
US20160096830A1,O=C(NCCCC[C@H](NC(=O)[C@H]1CCCN(C(=O)CCc2ccccc2)C1)C(=O)c1nc2ccccc2s1)OCc1ccccc1>>NCCCC[C@H](NC(=O)[C@H]1CCCN(C(=O)CCc2ccccc2)C1)C(=O)c1nc2ccccc2s1,,CC(=O)O,,Br,O,test
US20130317031A1,CC(C)OC(=O)/C=C\I.FC(F)(F)c1cc(-c2nc[nH]n2)cc(C(F)(F)F)c1>>CC(C)OC(=O)/C=C\n1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1,,CN(C)C=O,,C1CN2CCN1CC2,,test
US05726195,C#Cc1ccc(C#N)cc1.O=[N+]([O-])c1ccc(Br)o1>>N#Cc1ccc(C#Cc2ccc([N+](=O)[O-])o2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,,CCN(CC)CC,,test
US20140275152A1,CN(C)/C=C/C(=O)c1ncccc1CO[Si](C)(C)C(C)(C)C.NNC1CCCC1>>OCc1cccnc1-c1ccnn1C1CCCC1,,CCO,,Cl,,test
US20070149542A1,BrCCC1OCCO1.CS(=O)(=O)c1cccc(C2CCNCC2)c1F>>CS(=O)(=O)c1cccc(C2CCN(CCC3OCCO3)CC2)c1F,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US20120245161A1,COCCn1ccc2c(C=O)cccc21.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COCCn1cc(C(=O)C(F)(F)F)c2c(C=O)cccc21,,CN(C)C=O,,,,test
US20140275528A1,CS(=O)(=O)Cl.OCCc1ccc(Cl)cc1>>CS(=O)(=O)OCCc1ccc(Cl)cc1,,ClCCl,O,,,test
US04623657,OC1(Cc2ccccc2F)CCCCCC1>>c1ccc2c(c1)CC1(CCCCCC1)O2,,c1ccccc1,,CN(C)C=O,[H-].[Na+],test
US04282245,COC(=O)C(C)c1ccc2c(c1)C(=O)Cc1cc(N)ccc1S2>>CC(C(=O)O)c1ccc2c(c1)C(=O)Cc1cc(N)ccc1S2,,O,,CO,[K+].[OH-],test
US20150105351A1,COc1ccccc1Oc1cc(I)cc([N+](=O)[O-])c1>>COc1ccccc1Oc1cc(N)cc(I)c1,[Fe],CCO,,[Cl-].[NH4+],,test
US20120264157A1,CCCCCCOC(C)(COS(=O)(=O)[O-])OCCCCCC.Cc1ccccc1>>CCCCCCOC(=O)C(C)(OCCCCCC)OCCCCCC,,Cc1ccccc1,,O,,test
US20030004181A1,CCCN(CCC(=O)OCC)C(=O)c1ccc(NC)c(NC(=O)CCl)c1>>CCCN(CCC(=O)OCC)C(=O)c1ccc2c(c1)nc(CCl)n2C,,CC(=O)O,,,,test
US20160221941A1,COC(=O)C(C)(COS(=O)(=O)c1ccc(C)cc1)NC(=O)OCC1c2ccccc2-c2ccccc21.COc1ccc(C[Se-]=[Se])cc1>>COC(=O)C(C)(C[Se]Cc1ccc(OC)cc1)NC(=O)OCC1c2ccccc2-c2ccccc21,,CCO,,,,test
US05998436,CC(C)(C)N.Fc1nc(F)c(F)c(F)c1F>>CC(C)(C)Nc1c(F)c(F)nc(F)c1F,,ClC(Cl)Cl,,CC#N,,test
US20100317607A1,Clc1nc(N2CCCCC2)nc2ccccc12.NCCc1ccccc1>>C[C@H](Nc1nc(N2CCCCC2)nc2ccccc12)c1ccccc1,,CC(C)O,,CCN(CC)CC,,test
US20130331377A1,CCCc1cc(=O)[nH]c(SC)n1.Nc1ccc(F)cc1>>CCCc1cc(=O)[nH]c(Nc2ccc(F)cc2)n1,,CCO,,C,,test
US04064350,C#CCOC1CCCCO1.C[Si](C)(C)Cl>>C[Si](C)(C)C#CCOC1CCCCO1,,CCCCCC,CCOCC,O,[Li]CCCC,test
US20160235716A1,O=C(Cl)C(=O)Cl.O=C(O)/C=C/CN1CCCCC1>>O=C(Cl)/C=C/CN1CCCCC1,CN(C)C=O,ClCCl,,,,test
US20080027070A1,CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc(Nc3ncc(NC(=O)c4cc(NC(=O)c5ccc(C#N)cc5)ccc4Cl)cn3)cc2)CC1.O=C(O)C(F)(F)F>>N#Cc1ccc(C(=O)Nc2ccc(Cl)c(C(=O)Nc3cnc(Nc4ccc(S(=O)(=O)C5CCNCC5)cc4)nc3)c2)cc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20090143383A1,COc1nc(OC2CCN(Cc3ccccc3)C2)ccc1[N+](=O)[O-]>>COc1nc(OC2CCN(Cc3ccccc3)C2)ccc1N,[Fe],CC(=O)O,,,,test
US20120214837A1,CCOc1cccc2ncc(CO)cc12.ClCCl.O=S(Cl)Cl>>CCOc1cccc2ncc(CCl)cc12.Cl,,ClCCl,,,,test
US20110040092A1,C=CCCCCCCCCCC.OF>>CCCCCCCCCCC1CO1,,CC#N,,ClCCl,O,test
US20100305085A1,CC(C)(C)COc1ccc(-n2[nH]cc(-n3ccnc3)c2=O)nc1.Cl>>CC(C)(C)COc1ccc(-n2[nH]cc(-n3ccnc3)c2=O)nc1.Cl,,C1COCCO1,,,,test
US20130165333A1,COP(=O)(OC)C(Br)c1ccccc1>>O=P(O)(O)C(Br)c1ccccc1,,ClCCl,,C[Si](C)(C)Br,,test
US20100247668A1,COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1.O=S(=O)(O)c1ccc2ccccc2c1>>COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1.O=S(=O)([O-])c1ccc2ccccc2c1,,C1CCOC1,,Cl,CC(C)(C)[O-].[K+],test
US05208247,CC(=O)NCc1ccncc1.CCCCCCCCCCCCCCOc1ccc(CBr)cc1>>CCCCCCCCCCCCCCOc1ccc(CN(Cc2ccncc2)C(C)=O)cc1,,C1CCOC1,,[H-].[Na+],,test
US20160016908A1,CC[C@H]1[C@H](C)[C@@H](N)c2cc(Br)ccc2N1C(C)=O.Fc1ncccn1>>CC[C@H]1[C@H](C)[C@@H](Nc2ncccn2)c2cc(Br)ccc2N1C(C)=O,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US20040253181A1,CC(C)(C)OC(=O)NCCCOCCOCCOCCCNC(=O)CNCCCOCCOCCOCCCN.CCOc1c(OCC)c(=O)c1=O>>CCOc1c(NCCCOCCOCCOCCCNCC(=O)NCCCOCCOCCOCCCNC(=O)OC(C)(C)C)c(=O)c1=O,,ClCCl,,,,test
US05281602,CCCCC(=N)N.CCOC(=O)C1CN(C(=O)C(C)(C)C)CCC1=O>>CCCCc1nc2c(c(=O)[nH]1)CN(C(=O)C(C)(C)C)CC2,,CCO,CO,Cl,C[O-].[Na+],test
US06133253,O=C(OCc1ccccc1)N1CC[C@@H]1CO.Oc1cccnc1>>O=C(OCc1ccccc1)N1C=CC=C(OC[C@H]2CCN2)C1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06429214B1,CCOC(=O)CC1Cc2cc(OCCCNC(=N)N)ccc2NC1=O>>N=C(N)NCCCOc1ccc2c(c1)CC(CC(=O)O)C(=O)N2,,CCO,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20040171654A1,CC(C)(C)c1ccc(S(=O)(=O)Cl)cc1.Nc1ccc(Cl)cc1C(=O)c1cccnc1>>CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2C(=O)c2cccnc2)cc1,,O,c1ccncc1,,,test
US04117019,Cc1ccccc1CCl.c1ccccc1>>Cc1ccccc1Cc1ccccc1,,c1ccccc1,,O=S(=O)(O)O,,test
US20050261294A1,CC(=O)c1ccc(F)cc1.C[C@@H]1CC[C@H](O)CC1>>CC(=O)c1ccc(O[C@@H]2CC[C@H](C)CC2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US05523440,CCCBr.Fc1ccc(-c2ccc(CC[C@@H]3CC[Si@@H](Cl)CC3)cc2)cc1>>CCC[Si@@H]1CC[C@@H](CCc2ccc(-c3ccc(F)cc3)cc2)CC1,,C1CCOC1,,[Mg],,test
US20060183768A1,CCOC(=O)C(C(=O)OCC)c1cc(NCc2ccccn2)c2c(-c3ccccc3)csc2n1>>OCC(CO)c1cc(NCc2ccccn2)c2c(-c3ccccc3)csc2n1,,C1CCOC1,,CC(C)C[Al+]CC(C)C.[H-],,test
US05693651,Br.C=CC(=O)OC.CCc1ccc(COc2ccc3cc(N)cnc3c2)nc1>>CCc1ccc(COc2ccc3cc(CC(Br)C(=O)OC)cnc3c2)nc1,,CC(C)=O,CO,O=N[O-].[Na+],,test
US20110190258A1,C=CCc1cc(C#N)ccc1O.O=C(Cl)C(Cl)(Cl)Cl>>C=CCc1cc(C#N)ccc1OC(=O)C(Cl)(Cl)Cl,,ClCCl,,CCN(CC)CC,,test
US05910506,CI.Cc1cc(C)cc(Sc2[nH]cnc2C(C)C)c1>>Cc1cc(C)cc(Sc2c(C(C)C)ncn2C)c1,,CN(C)C=O,,[H-].[Na+],,test
US20150045378A1,CC(C)CO.Clc1ncc(Br)c(Cl)n1>>CC(C)COc1nc(Cl)ncc1Br,,C1CCOC1,,O,[H-].[Na+],test
US20070149810A1,CC(C)(C)C(=O)CBr.CCC(CC)(c1ccc(O)c(C)c1)c1cc2cc(OC)ccc2s1>>CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc2cc(OC)ccc2s1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110021522A1,Nc1cccc(-c2cn3ccccc3n2)c1.O=C(O)c1cc2cc(O)ccc2oc1=O>>O=C(Nc1cccc(-c2cn3ccccc3n2)c1)c1cc2cc(O)ccc2oc1=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060252768A1,O=S(Cl)Cl.O[C@H](CNCc1ccccc1)c1ccc(Cl)cc1>>O=S1O[C@@H](c2ccc(Cl)cc2)CN1Cc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20090143353A1,C=Cc1c(C)c(C#N)c2nc(C(=O)N(C)C)oc2c1F.CN(C)[C@H]1CCNC1>>C=Cc1c(C)c(C#N)c2nc(C(=O)N(C)C)oc2c1N1CC[C@H](N(C)C)C1,,CCOC(C)=O,CS(C)=O,CCN(CC)CC,O=C([O-])O.[Na+],test
US20140087949A1,CCOC(=O)/C=C(\C#CC1(O)C(C)=CC(=O)CC1(C)C)C(F)(F)F.CON>>CCOC(=O)/C=C(\C#CC1(O)C(C)=CC(=NOC)CC1(C)C)C(F)(F)F,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20120232051A1,CNc1cnccc1-c1ccccc1.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnccc1-c1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20100280029A1,CC1CNCC(C)O1.O=S(=O)(c1ccccc1)n1ncc2c(-c3ncc(CBr)o3)cc(Cl)cc21>>C[C@@H]1CN(Cc2cnc(-c3cc(Cl)cc4c3cnn4S(=O)(=O)c3ccccc3)o2)C[C@@H](C)O1,,ClCCl,,,,test
US20050272779A1,CC(Cl)C(=N)NO.Cc1cccc(C(=O)Cl)c1>>Cc1cccc(-c2nc(C(C)Cl)no2)c1,,ClCCl,,CCN(CC)CC,,test
US20120071536A1,C=CCN1CC2CC1(C(=O)N1CCOCC1)C2.[Li]c1ccccc1>>C=CCN1CC2CC1(C(=O)c1ccccc1)C2,,C1CCOC1,,O,,test
US20130065913A1,COC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)c2nn(CCCN(C)C(=O)OC(C)(C)C)c(=O)n2C1c1ccc(C#N)cc1.CS(=O)(=O)Cl>>COC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)c2nn(CCCN(C)S(C)(=O)=O)c(=O)n2C1c1ccc(C#N)cc1,,ClCCl,O=C(O)C(F)(F)F,CCN(CC)CC,,test
US04772606,Nc1nc2c(ncn2Cc2cccs2)c(=O)[nH]1.O=C1CCC(=O)N1Br>>Nc1nc2c(nc(Br)n2Cc2cccs2)c(=O)[nH]1,,CN(C)C=O,O,,,test
US20160046637A1,CC(C)(C)c1nc(Cl)c2cc[nH]c2n1.FC1(F)CCNC1>>CC(C)(C)c1nc(N2CCC(F)(F)C2)c2cc[nH]c2n1,,CCO,,CCN(C(C)C)C(C)C,Cl,test
US04728645,Cl.OCc1ccc(-c2cccc3cncn23)cc1>>Cc1ccc(C2CCCc3cncn32)cc1.Cl,[Pd],CCO,,[H][H],,test
US20080045714A1,CSc1cc(C)nc(SC)c1NC(=O)CO.c1ccc2[nH]c(SCCN3CCNCC3)nc2c1>>CSc1cc(C)nc(SC)c1NC(=O)CN1CCN(CCSc2nc3ccccc3[nH]2)CC1,,CN(C)C=O,O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05885986,CN1Cc2c(C(N)=S)ncn2-c2ccc(F)cc2C1=O.O=C(CCl)CCl>>CN1Cc2c(-c3nc(CCl)cs3)ncn2-c2ccc(F)cc2C1=O,,C1COCCO1,,,,test
US20140309417A1,CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=C[C@@H]4OC45C[C@@H](O)CC[C@]5(C)[C@H]3CC[C@@]21C.NCCCN>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=C[C@@H](NCCCN)[C@@]4(O)C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C,,COC(C)(C)C,,CCCCO,,test
US04691041,CO.O=C1OCCO1.OCCO>>COC(=O)OC.O=C1OCCO1,,OCCO,,,,test
US04686292,CCOC(=O)C1=C(O)C(=O)c2ccccc2C1=O.CCOC(=O)Cl>>CCOC(=O)OC1=C(C(=O)OCC)C(=O)c2ccccc2C1=O,,C1CCOC1,,CCN(CC)CC,,test
US20140364414A1,CC(C)(C)OC(=O)N1CCN(c2ccc(-c3cnc(N4CCOCC4)c4nc(/C=C/c5ccc6ccccc6n5)cn34)cn2)CC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(-c3cnc(N4CCOCC4)c4nc(CCc5ccc6ccccc6n5)cn34)cn2)CC1,,CO,,,,test
US20160102083A1,CC(=O)CCCCl.COC(=O)c1csc(N)c1C>>COC(=O)c1csc(N2CCCC2C)c1C,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US04826986,CCOC(=O)C1CC2(CCC1N)OCCO2>>CCOC(=O)[C@@H]1CC2(CC[C@H]1N)OCCO2,,CCO,,[Na],,test
US20090156516A1,CC(=O)OC[C@@H]1[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](c2ccc(Cl)c(Cc3ccc(C(C)=O)cc3)c2)[C@H]1OC(C)=O>>CC(=O)c1ccc(Cc2cc([C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)[C@@H]3O)ccc2Cl)cc1,,CO,,Cl,[Na+].[OH-],test
US05554746,COC(=O)C(C)Br.Cc1c[nH]c(=O)[nH]c1=O>>Cc1cn(C(C)C(=O)O)c(=O)[nH]c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150291549A1,Cc1c(C#N)cncc1CO.O=S(Cl)Cl>>Cc1c(C#N)cncc1CCl,,ClCCl,,,,test
US04038396,O=[N+]([O-])c1cccc(-c2nc3ncccc3o2)c1>>Nc1cccc(-c2nc3ncccc3o2)c1,[Pd],CCO,,,,test
US20070004725A1,COC(=O)CCc1ccc(Oc2ccc(CC(NC(=O)OC(C)(C)C)C(=O)N3CCN(C(C)=O)CC3)cc2)cc1>>CC(=O)N1CCN(C(=O)C(Cc2ccc(Oc3ccc(CCC(=O)O)cc3)cc2)NC(=O)OC(C)(C)C)CC1,,C1CCOC1,O,[Li+].[OH-],,test
US05587388,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.O=COCCl>>COC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US04804661,Clc1ccc(CCN2CCNCC2)cc1.O=C(Cl)c1ccccc1F>>Cl.O=C(c1ccccc1F)N1CCN(CCc2ccc(Cl)cc2)CC1,,ClCCl,,,,test
US06225352B1,COc1cc(COc2ccccc2OS(=O)(=O)c2ccc(C)cc2)cc(OC)c1>>COc1cc(COc2ccccc2O)cc(OC)c1,,CCO,O,CC(=O)O,[K+].[OH-],test
US20090298807A1,CC(C)C(N)=S.CCOC(=O)C(Cl)C=O>>CCOC(=O)c1cnc(C(C)C)s1,,CC(C)=O,,,,test
US05665719,CI.COC(=O)c1ccc(OC2CCN(C(=O)OC(C)(C)C)C2)cc1O>>COC(=O)c1ccc(OC2CCN(C(=O)OC(C)(C)C)C2)cc1OC,,CN(C)C=O,,[H-].[Na+],,test
US20120230932A1,CCO[Si](CCCI)(OCC)OCC.O=C(Oc1ccc(CO)cc1)c1ccccc1>>CCO[Si](CCCOCc1ccc(OC(=O)c2ccccc2)cc1)(OCC)OCC,,C1CCOC1,,[H-].[Na+],,test
US20090099177A1,COC(=N)c1cccc(Cc2cc(Cl)ccc2OCC(C)C)n1.COC(=O)c1ccc(N)c(N)c1>>COC(=O)c1ccc2[nH]c(-c3cccc(Cc4cc(Cl)ccc4OCC(C)C)n3)nc2c1,,CCO,,Cl,,test
US20030130227A1,CCCCCCCCCCCCCCCC(=O)NC[C@@H](OCc1ccc(OC)cc1)[C@@H]1C[C@@H](OC(C)=O)[C@H](n2ccc(=O)[nH]c2=O)O1>>CCCCCCCCCCCCCCCC(=O)NC[C@@H](O)[C@@H]1C[C@@H](OC(C)=O)[C@H](n2ccc(=O)[nH]c2=O)O1,,CCOCC,ClCCl,O=C(O)C(F)(F)F,,test
US05776929,CC(C)(C)OC(=O)NC1C(=O)N(CC(=O)C2CC2)c2ccccc2N(CC(=O)C2CC2)C1=O>>NC1C(=O)N(CC(=O)C2CC2)c2ccccc2N(CC(=O)C2CC2)C1=O,,CCOC(C)=O,,Cl,,test
US20040158030A1,O=[N+]([O-])c1cc(CO)cc([N+](=O)[O-])c1.OCCCCCCCCCCCCBr>>O=[N+]([O-])c1cc(COCCCCCCCCCCCCO)cc([N+](=O)[O-])c1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20100267714A1,COc1ccc2oc(=O)[nH]c2c1.COc1cccc(CBr)c1>>COc1cccc(Cn2c(=O)oc3ccc(OC)cc32)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04769402,Nc1ccc(O)cc1.O=C1CCC(=O)O1>>O=C1CCC(=O)N1c1ccc(O)cc1,,CN(C)C=O,O,,,test
US20140200206A1,COc1cc(C(=O)NC2CN(C)C2)ccc1[N+](=O)[O-]>>COc1cc(C(=O)NC2CN(C)C2)ccc1N,[Pd],C1CCOC1,CO,,,test
US20060183749A1,CS(=O)(=O)Cl.O=c1cc(CO)occ1OCCCCCSc1ccnc2cc(C(F)(F)F)ccc12>>CS(=O)(=O)OCc1cc(=O)c(OCCCCCSc2ccnc3cc(C(F)(F)F)ccc23)co1,,ClCCl,,CCN(CC)CC,,test
US20070072847A1,C=CC(=O)OCC.CC(C)(C)OC(=O)N1CCC(C2CCNCC2)CC1>>CCOC(=O)CCN1CCC(C2CCN(C(=O)OC(C)(C)C)CC2)CC1,,CCO,,,,test
US20080318940A1,C#C[Si](C)(C)C.CC(C)c1nc2c(I)c(N)ccc2c(=O)n1-c1ccc(Cl)cc1>>CC(C)c1nc2c(C#C[Si](C)(C)C)c(N)ccc2c(=O)n1-c1ccc(Cl)cc1,[Cu]I,CN(C)C=O,,CCN(CC)CC,,test
US20080293771A1,CC(C)N1CC[C@@H](N(C)C(=O)OCc2ccccc2)C1>>CN[C@@H]1CCN(C(C)C)C1,[Pd],CCO,,,,test
US20040044204A1,ClC1NC(C=Cc2cccc3ccccc23)=Nc2ccccc21.NCC1CCCC(CN)C1>>NCC1CCCC(CNc2nc(C=Cc3cccc4ccccc34)nc3ccccc23)C1,,CCO,,,,test
US20140088159A1,O=C(CCC(NC1(C(=O)OC2CCCC2)CCCC1)c1ccccc1)NO>>O=C(CCc1ccc(CNC2(C(=O)O)CCCC2)cc1)NO,,C1CCOC1,,O,[Li+].[OH-],test
US20070249698A1,CCOC(=O)C(Cc1nc(-c2ccc(C)cc2)c(-c2ccc(C)cc2)[nH]1)c1cccc(C)c1.CI>>COC(=O)C(Cc1nc(-c2ccc(C)cc2)c(-c2ccc(C)cc2)n1C)c1cccc(C)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070249606A1,CCCS(=O)(=O)N1CCC(CN)(C(=O)N2CCOCC2)CC1.O=C(Cl)c1ccc(Cl)cc1Cl>>CCCS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(C(=O)N2CCOCC2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110003790A1,Nc1cccc(C(F)(F)F)c1.O=c1[nH]cnc2cc(Cl)nc(Cl)c12>>O=c1[nH]cnc2cc(Cl)nc(Nc3cccc(C(F)(F)F)c3)c12,,C1CCOC1,,,,test
US20100125087A1,N#Cc1ncccc1Br.[Zn]>>N#Cc1ncccc1[Zn+].[Br-],,C1CCOC1,,,,test
US04395577,C=CC(N)=O.C=O.Cc1ccc([N+](=O)[O-])cc1>>C=CC(=O)NCc1cc([N+](=O)[O-])ccc1C,,O=S(=O)(O)O,,,,test
US20090170913A1,CN(C)C1CCN(c2nc3cc([N+](=O)[O-])ccc3o2)C1>>CN(C)C1CCN(c2nc3cc(N)ccc3o2)C1,,CC(=O)O,O,,,test
US20060120956A1,O=C1NC(=O)C(c2ccc(Oc3ccc(Br)cc3)cc2)(N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)C(=O)N1>>O=[N+]([O-])c1ccc(N2CCNCC2)cc1,,CO,,,,test
US20120028973A1,CN(C)C=O.FC(F)(F)Oc1ccc(-c2ncc(Br)cn2)cc1>>O=Cc1cnc(-c2ccc(OC(F)(F)F)cc2)nc1,,C1CCOC1,,[Li]CCCC,,test
US20070197478A1,O=CCc1cc(NCc2ccccc2)c([N+](=O)[O-])c(NCc2ccccc2)n1>>O=[N+]([O-])c1c(NCc2ccccc2)cc(CCO)nc1NCc1ccccc1,,ClCCl,,[BH4-].[Na+],,test
US20110319394A1,Nc1cccnc1Nc1ccc(N2CCn3c2nc2ccccc23)cc1.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2cccnc2n1-c1ccc(N2CCn3c2nc2ccccc23)cc1,,C1CCOC1,,,,test
US20140066425A1,Nc1ccc(CCCC2=NCCN2)cc1.O=C(Cl)OCc1ccccc1>>O=C(Nc1ccc(CCCC2=NCCN2)cc1)OCc1ccccc1,,CN(C)C=O,,,,test
US20040147748A1,CC1(C)OC[C@H](c2cnc(NC(=O)[C@H](CC3CCCC3)c3ccc(S(C)(=O)=O)c(Cl)c3)cn2)O1>>CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)Nc2cnc([C@H](O)CO)cn2)cc1Cl,,C1CCOC1,,Cl,,test
US20050107339A1,CCOc1cc(C(=CC#N)c2ccc(OC)c(N)c2)ccc1OC.O=C=NS(=O)(=O)c1ccccc1>>CCOc1cc(C(=CC#N)c2ccc(OC)c(NC(=O)NS(=O)(=O)c3ccccc3)c2)ccc1OC,,C1CCOC1,,,,test
US20050070549A1,CC(C)(C)OC(=O)N1CC[C@@H](OCc2ccc(Cl)cc2)C1>>Clc1ccc(CO[C@@H]2CCNC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160122339A1,O=C1CCC(=O)N1I.Oc1ccnc2ccc(Br)cc12>>Oc1c(I)cnc2ccc(Br)cc12,,CCOC(C)=O,,,,test
US20040132727A1,COc1cc2nccc(Oc3cc(C)c(N)cc3C)c2cc1OC.Cc1ccc(CS)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3cc(C)c(NC(=S)OCc4ccc(C)cc4)cc3C)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US04014907,Cc1cc2c(cc1C)C(=O)C=CC2=O.Nc1ccccc1>>Cc1cc2c(cc1C)C(=O)C(Nc1ccccc1)=CC2=O,,CCO,,,,test
US20100273764A1,CC(C)(C)OC(=O)Nc1ccc(N)cn1.COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cccnc3F)n2)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cccnc3Nc3ccc(NC(=O)OC(C)(C)C)nc3)n2)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04296239,C1=CCNCC1.Cc1nnc2n1-c1ccc(Cl)cc1C(=S)NC2>>Cc1nnc2n1-c1ccc(Cl)cc1C(N1CC=CCC1)=NC2,,O,,,,test
US20100029615A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1CCCC(C(=O)O)C1>>CC(C)(C)OC(=O)C1CCCC(C(=O)O)C1,,O,,C1CCOC1,CCN(C(C)C)C(C)C,test
US20150336949A1,COc1cc(-c2cnc3c(c2)c(-c2cnn(Cc4cccc(F)c4)c2)cn3S(=O)(=O)c2ccc(C)cc2)ccc1N1CCNCC1.C[C@H]1CO1>>COc1cc(-c2cnc3c(c2)c(-c2cnn(Cc4cccc(F)c4)c2)cn3S(=O)(=O)c2ccc(C)cc2)ccc1N1CCN(C[C@H](C)O)CC1,,CCO,,CCN(C(C)C)C(C)C,Cl,test
US20150368259A1,CN1CCN(Cc2ccc(-n3cc(N)c(C(N)=O)n3)cc2)CC1.Clc1ncnc2sccc12>>CN1CCN(Cc2ccc(NC(=O)c3n[nH]cc3Nc3ncnc4sccc34)cc2)CC1,,CO,ClC(Cl)Cl,CC(=O)O,[Na+].[OH-],test
US20150238601A1,Cc1cnc(-c2cccc(OCC(=O)NC3CC3)c2)nc1N(C(=O)OC(C)(C)C)c1ccc2c(cnn2C(=O)OC(C)(C)C)c1.Cl>>Cc1cnc(-c2cccc(OCC(=O)NC3CC3)c2)nc1Nc1ccc2[nH]ncc2c1.Cl,,CCOC(C)=O,,,,test
US20120302608A1,C[Sn](C)(C)C.Cc1nc2ncccn2c1-c1ccc(Br)cc1>>Cc1ccc(-c2c(C)nc3ncccn23)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,,,test
US20080113978A1,CCC(CC)c1cc(C)nn2c(-c3sc(Br)nc3C(F)(F)F)c(C)nc12.CNC>>CCC(CC)c1cc(C)nn2c(-c3sc(N(C)C)nc3C(F)(F)F)c(C)nc12,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140274958A1,C=CC1=C(C(=O)OCc2ccc(OC)cc2)N2C(=O)[C@@H](/N=C\c3ccccc3O)[C@H]2SC1.CC(C)(C)OC(=O)CO/N=C(\C(=O)OS(C)(=O)=O)c1csc(N)n1>>C=CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)/C(=N\OCC(=O)O)c3csc(N)n3)[C@H]2SC1,,COC(C)(C)C,,ClCCl,O,test
US20090274984A1,CC(C)(C)OC(=O)C1C2CC3C(OC(=O)C31)C2O.O=C(Cl)CCl>>CC(C)(C)OC(=O)C1C2CC3C(OC(=O)C31)C2OC(=O)CCl,,C1CCOC1,,O,c1ccncc1,test
US20100168096A1,NC(N)=NC(=O)c1ccc2c(c1)C(=O)c1sccc1-2>>NC(N)=NC(=O)c1ccc2c(c1)C(O)c1sccc1-2,,CO,,[BH4-].[Na+],,test
US20050250797A1,CCBr.COc1cc2c(Cl)ncnc2cc1O>>CCOc1cc2ncnc(Cl)c2cc1OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100249101A1,CC(=O)O.CC(=O)c1ccc(C#N)c(Br)c1>>CC(=O)c1ccc(C(=O)O)c(Br)c1,,O,O=S(=O)(O)O,[Na+].[OH-],,test
US20120196864A1,CNC1=NC(=O)S/C1=C\c1ccc(OCc2ccc(C(F)(F)F)cc2C(F)(F)F)c(N)c1.CS(=O)(=O)Cl>>CNC1=NC(=O)S/C1=C\c1ccc(OCc2ccc(C(F)(F)F)cc2C(F)(F)F)c(NS(C)(=O)=O)c1,,C1CCOC1,,CCN(CC)CC,[Cl-].[NH4+],test
US05436247,CCOC(=O)c1c(Cn2cncn2)nc2cc(OC)c(OC(C)C)cc2c1-c1ccc(OC(C)C)c(OC(C)C)c1>>CCOC(=O)c1c(Cn2cncn2)nc2cc(OC)c(O)cc2c1-c1ccc(O)c(O)c1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,O,,test
US20080293770A1,Cc1cc(NC2CCN(C(=O)OC(C)(C)C)CC2)c([N+](=O)[O-])cc1OC(C)C>>Cc1cc(NC2CCN(C(=O)OC(C)(C)C)CC2)c(N)cc1OC(C)C,[Ni],CCO,,NN,O,test
US20100204163A1,COC(=O)[C@@H](Oc1nc(C)cc(CO)n1)C(OC)(c1ccccc1)c1ccccc1>>COC(c1ccccc1)(c1ccccc1)[C@H](Oc1nc(C)cc(CO)n1)C(=O)O,,CO,O,[Na+].[OH-],,test
US20100278833A1,COC(=O)c1sc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)cc1O[C@@H](C)c1ccccc1C(F)(F)F.N>>C[C@H](Oc1cc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F,,CO,,,,test
US20080027065A1,C[C@H]1CN(Cc2ccc(N(C)C(=O)c3ccc(Cl)nc3)cc2)CCN1C(=O)OC(C)(C)C.Oc1ccccc1F>>C[C@H]1CN(Cc2ccc(N(C)C(=O)c3ccc(Oc4ccccc4F)nc3)cc2)CCN1C(=O)OC(C)(C)C,,CN(C)C=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20110092504A1,Nc1cc(-c2ccc3nccc(N4CCOCC4)c3c2)cnc1Cl.O=S(=O)(Cl)c1c(Cl)cccc1Cl>>O=S(=O)(Nc1cc(-c2ccc3nccc(N4CCOCC4)c3c2)cnc1Cl)c1c(Cl)cccc1Cl,,C1CCOC1,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US05952321,CCC[C@@H](NC(=O)N1C(=O)C(CC)(CC)[C@@H]1Oc1ccc([C@H](C)NC)cc1)c1ccc(C)cc1.COCC(=O)Cl>>CCC[C@@H](NC(=O)N1C(=O)C(CC)(CC)[C@@H]1Oc1ccc([C@H](C)N(C)C(=O)COC)cc1)c1ccc(C)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100160303A1,CC(C)(C)[Si](C)(C)Cl.NC(=O)c1ccc(Br)c2c1[nH]c1cc(C3(O)CC3)ccc12>>CC(C)(C)[Si](C)(C)OC1(c2ccc3c(c2)[nH]c2c(C(N)=O)ccc(Br)c23)CC1,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US20070185153A1,O=c1cc(CCCO)c(=O)[nH][nH]1>>O=c1cc2c(n[nH]1)OCCC2,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05565472,Cn1c(=O)c(NC(=O)OCc2ccc([N+](=O)[O-])cc2)c(-c2ccccc2Cl)c2cc(Cl)ccc21>>Cn1c(=O)c(N)c(-c2ccccc2Cl)c2cc(Cl)ccc21,[Ni],C1COCCO1,CO,,,test
US20040209881A1,CN1CCNCC1.COc1ccc(Nc2nc(Cl)nc(NC3CCCCCC3)n2)cc1Cl>>COc1ccc(Nc2nc(NC3CCCCCC3)nc(N3CCN(C)CC3)n2)cc1Cl,,C1COCCO1,O,[Na+].[OH-],,test
US20120264737A1,COC(=O)c1cc(C(=N)N)c(C)cc1C.O=C(CBr)[C@@H]1CCCO1>>COC(=O)c1cc(-c2ncc([C@@H]3CCCO3)[nH]2)c(C)cc1C,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US05244908,O=C1c2ccccc2CN1CCBr.Sc1cccc2nccn12>>O=C1c2ccccc2CN1CCSc1cccc2nccn12,,CCO,,CCN(CC)CC,,test
US20150315198A1,Clc1ncnc2[nH]ncc12.O=c1ccc(Cl)cn1Cc1ccc(CO)cc1>>O=c1ccc(Cl)cn1Cc1ccc(Cn2cc3c(Cl)ncnc3n2)cc1,,ClCCl,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060128613A1,C=CCBr.O=C(CCc1ccc(OCc2ccccc2)cc1)N1C(=O)OC[C@@H]1Cc1ccccc1>>C=CCC(Cc1ccc(OCc2ccccc2)cc1)C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20130296380A1,Nc1cccc(S(F)(F)(F)(F)F)c1.O=C1CCC(=O)N1Br>>Nc1ccc(Br)c(S(F)(F)(F)(F)F)c1,,CN(C)C=O,,O,,test
US20120196869A1,COCC#Cc1ccc(C(=O)OC)cc1F>>COCC#Cc1ccc(C(=O)O)cc1F,,C1CCOC1,,CO,[Na+].[OH-],test
US20050032873A1,COC(=O)c1ccc(F)c2c1OCC=C2>>O=C(O)c1ccc(F)c2c1OCC=C2,,CCO,,O,[Na+].[OH-],test
US20090036492A1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.O=Cc1ccc(OCc2ccc(F)cc2)c2ccccc12>>COc1cc(O)c2c(c1C(=O)NCc1ccc(OCc3ccc(F)cc3)c3ccccc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20140057915A1,CC(C)(F)C(=O)CC#N.Cc1ccc(NN)cc1>>C=C(C)c1cc(N)n(-c2ccc(C)cc2)n1,,CCO,,Cl,,test
US20030139406A1,COc1ccc(C2CC(=O)N(CC(=O)[O-])C2)cc1OC1CCCC1>>COc1ccc(C2CC(=O)N(CC(=O)O)C2)cc1OC1CCCC1,,CO,,O,[K+].[OH-],test
US20050245503A1,NNc1ncc(C(=O)O)cc1Cl.S=C=NC1c2ccccc2CCc2ccncc21>>O=C(O)c1cnc(NNC(=S)NC2c3ccccc3CCc3ccncc32)c(Cl)c1,,CC(=O)N(C)C,,,,test
US20100076026A1,Clc1ccc(-n2nc3ccccc3c2Nc2cccnc2)cc1.O=C=NC1CCCCC1>>O=C(NC1CCCCC1)N(c1cccnc1)c1c2ccccc2nn1-c1ccc(Cl)cc1,,ClCCCl,,CCN(CC)CC,,test
US09186423B1,CC(=O)c1ccc2cc(N(C)CCO)ccc2c1.N#CCC#N>>CC(=C(C#N)C#N)c1ccc2cc(N(C)CCO)ccc2c1,,c1ccncc1,,CCOCC,,test
US20120197027A1,CC(C)NC(C)C.COc1cc2c(Oc3ccc4[nH]cc(C)c4c3)ncnc2cc1OC[C@H]1CO1>>COc1cc2c(Oc3ccc4[nH]cc(C)c4c3)ncnc2cc1OC[C@H](O)CN(C(C)C)C(C)C,,CN(C)C=O,,,,test
US20130012491A1,CCOC(=O)CCCBr.CCc1c(-c2cnc(-c3ccc(OC(C)C)c(Cl)c3)nc2)cccc1C1CCNCC1>>CCOC(=O)CCCN1CCC(c2cccc(-c3cnc(-c4ccc(OC(C)C)c(Cl)c4)nc3)c2CC)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120190649A1,CCOC(=O)CCN(Cc1ccc2cc(O[C@@H]3CC[C@@H](C(C)(C)C)CC3)ccc2c1)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N(CCC(=O)O)Cc1ccc2cc(O[C@@H]3CC[C@@H](C(C)(C)C)CC3)ccc2c1,,CCO,,Cl,[Na+].[OH-],test
US20070093548A1,COc1cc(Oc2ccc(C#N)cc2)ccc1F.O=C1CCC(=O)N1Br>>COc1cc(Oc2ccc(C#N)cc2)c(Br)cc1F,,CC#N,,CCOCC,O,test
US20160168137A1,CN.N#Cc1ccc(-c2cccc3ccccc23)nc1Cl>>CNc1nc(-c2cccc3ccccc23)ccc1C#N,,CS(C)=O,,C1CCOC1,,test
US06972297B2,CN.O=C(O)c1ccc(Cl)nc1>>CNc1ccc(C(=O)O)cn1.Cl,,CCO,CO,,,test
US20060014805A1,CCOC(=O)C(CC)Sc1nc2cc(Cl)ccc2s1>>CCC(Sc1nc2cc(Cl)ccc2s1)C(=O)O,,CCO,O,[K+].[OH-],,test
US20120115868A1,COC(=O)c1sc(CC(O)c2c(-c3ccc(F)cc3)nnn2C)nc1C>>Cc1nc(/C=C/c2c(-c3ccc(F)cc3)nnn2C)sc1C(=O)O,,O=S(=O)(O)O,,,,test
US06841559B1,C#C[Si](C)(C)C.O=c1c(OS(=O)(=O)C(F)(F)F)cc(S(=O)(=O)c2ccccc2)c2n1CCC2>>C[Si](C)(C)C#Cc1cc(S(=O)(=O)c2ccccc2)c2n(c1=O)CCC2,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCN(CC)CC,Cc1ccccc1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110065681A1,COC(=O)c1cc(-c2ccc(C)cc2)cc(S(=O)(=O)C2CCCC2)c1>>Cc1ccc(-c2cc(C(=O)O)cc(S(=O)(=O)C3CCCC3)c2)cc1,,C1CCOC1,,Cl,[Li+].[OH-],test
US20120184534A1,Brc1csc(-c2n[nH]c3ncccc23)n1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>Brc1csc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3ncccc23)n1,,CN(C)C=O,,[H-].[Na+],,test
US04818273,CCOC(=O)CC(C)=O.Nc1nc(S(=O)(=O)Nc2ccccc2C(F)(F)F)n[nH]1>>Cc1cc(O)n2nc(S(=O)(=O)Nc3ccccc3C(F)(F)F)nc2n1,,CO,,Cl,,test
US05616620,CC(C)(C)OC(=O)N[C@H](CCCNC(N)=N[N+](=O)[O-])C(=O)NCCc1ccc(O)cc1.O=C(O)C(F)(F)F>>NC(=N[N+](=O)[O-])NCCC[C@@H](N)C(=O)NCCc1ccc(O)cc1.O=C([O-])C(F)(F)F,,ClCCl,,,,test
US20130059853A1,COc1cccc(O)c1OC.O=C1CCC(=O)N1Br>>COc1ccc(Br)c(O)c1OC,,C1CCOC1,O,,,test
US20040167131A1,CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)CNCC2CC2)c(F)c1.O=C=Nc1ccc(Cl)cc1>>CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)CN(CC2CC2)C(=O)Nc2ccc(Cl)cc2)c(F)c1,,ClCCl,,CCN(CC)CC,,test
US05240948,CSCCCn1c(=N)sc2cc(OC(F)(F)F)ccc21.O=C(OO)c1cccc(Cl)c1>>CS(=O)CCCn1c(=N)sc2cc(OC(F)(F)F)ccc21,,C1COCCO1,,O,,test
US20150231114A1,N[C@H]1CCN(C(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C1.O=C1CCC(O)(c2ccc(-c3ncccn3)cn2)CC1>>O=C(NCC(=O)N1CC[C@H](NC2CCC(O)(c3ccc(-c4ncccn4)cn3)CC2)C1)c1cccc(C(F)(F)F)c1,,CC(C)CO,,Cl,[Na],test
US20090048306A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.FC(F)(F)Cc1ccccc1Br>>CC1(C)OB(c2ccccc2CC(F)(F)F)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US05674876,CC(=O)OC(C)=O.Cc1cc2c(c(C)c1O)C(C)CN2C(=O)C(C)C>>CC(=O)Oc1c(C)cc2c(c1C)C(C)CN2C(=O)C(C)C,,ClCCl,,c1ccncc1,,test
US20080004302A1,CC(C)(C)OC(=O)Nc1cccc(CCC(=O)O)c1.CI>>COC(=O)CCc1cccc(NC(=O)OC(C)(C)C)c1,,CN(C)C=O,,O=C([O-])O.[K+],,test
US20130158042A1,COc1cccc(C(=O)N2CCN(C(=O)OCc3ccccc3)C(C)(C)C2)n1>>COc1cccc(C(=O)N2CCNC(C)(C)C2)n1,[Pd],CO,,,,test
US20120010189A1,CC(C)(C)OC(=O)N1CC(OS(C)(=O)=O)C1.CN(C)C=O.Cc1cc(CN(C)C)ccc1O.O>>Cc1cc(CN(C)C)ccc1OC1CN(C(=O)OC(C)(C)C)C1.O=CO,,CN(C)C=O,,[H-].[Na+],,test
US20080045506A1,CCC(CC)N1CCN(C(=O)[C@H]2CCN(C(=O)OC(C)(C)C)C2)CC1>>CCC(CC)N1CCN(C(=O)[C@H]2CCNC2)CC1,,C1COCCO1,CO,Cl,,test
US20060281695A1,Nc1ccc(Cl)cc1Sc1ccc(Cl)cc1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=S(=O)(Nc1ccc(Cl)cc1Sc1ccc(Cl)cc1)C(F)(F)F,,ClCCl,,O,,test
US20110003787A1,COC[C@H](C)Oc1cc(Oc2ccc(C(=O)N3CCC3)cc2F)cc(-c2ccc(-c3nnc(C)o3)[nH]2)c1>>Cc1nnc(-c2ccc(-c3cc(Oc4ccc(C(=O)N5CCC5)cc4F)cc(O[C@@H](C)CO)c3)[nH]2)o1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20050131068A1,CCCCNCc1ccc(C(F)(F)F)cc1.CCOC(=O)[C@H](Cc1ccc(OCC(=O)O)cc1)OCC>>CCCCN(Cc1ccc(C(F)(F)F)cc1)C(=O)COc1ccc(C[C@H](OCC)C(=O)OCC)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20080306096A1,Cc1ccc([N+](=O)[O-])cc1N.O=C(O)c1ccc2c(Cl)ncnc2c1>>Cc1ccc([N+](=O)[O-])cc1Nc1ncc2ccc(C(=O)O)cc2n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150157736A1,CC(C)(C)[Si](C)(C)OCCN(CCC(=O)OCc1ccccc1)C(=O)CN(CCO[Si](C)(C)C(C)(C)C)C(=O)CN(CCO[Si](C)(C)C(C)(C)C)C(=O)CNC(=O)OCc1ccccc1>>CC(C)(C)[Si](C)(C)OCCN(CCC(=O)O)C(=O)CN(CCO[Si](C)(C)C(C)(C)C)C(=O)CN(CCO[Si](C)(C)C(C)(C)C)C(=O)CN,[Pd],CCOC(C)=O,,,,test
US20070167443A1,CCc1ccc(I)cn1.CON(C)C(=O)c1cn(Cc2cccc(Br)n2)c2ccccc2c1=O>>CCc1ccc(C(=O)c2cn(Cc3cccc(Br)n3)c3ccccc3c2=O)cn1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20100120741A1,Clc1ccc2nc(Cl)c(Cl)nc2c1.NN>>NNc1nc2cc(Cl)ccc2nc1Cl,,CCO,,O,,test
US20110065702A1,C[Si](C)(C)CCOCn1nc(I)c2ccc(C=O)cc21.OB(O)C1CC1>>C[Si](C)(C)CCOCn1nc(C2CC2)c2ccc(C=O)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20110257241A1,COC1(c2ccc(F)c(F)c2)CCN(C)C1.O=C(OO)c1cccc(Cl)c1>>COC1(c2ccc(F)c(F)c2)CC[N+](C)([O-])C1,,ClCCl,,,,test
US20060229337A1,Cc1c(NC(=O)c2cc3c(s2)CCCC3)cccc1-c1cn(C)c(=O)c(Nc2ccc(C(=O)N(C)CCO)c([N+](=O)[O-])c2)n1>>Cc1c(NC(=O)c2cc3c(s2)CCCC3)cccc1-c1cn(C)c(=O)c(Nc2ccc(C(=O)N(C)CCO)c(N)c2)n1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20110071152A1,N#CCC(=O)c1ccccc1Cl.N=CN(c1ccccc1)c1ccccc1>>N#CC(=CNc1ccccc1)C(=O)c1ccccc1Cl,,Cc1ccccc1,,,,test
US20040259859A1,CS(=O)(=O)Cl.Nc1cccc(C2C3CCC2CN(C(=O)OCc2ccccc2)C3)c1>>CS(=O)(=O)Nc1cccc(C2C3CCC2CN(C(=O)OCc2ccccc2)C3)c1,,c1ccncc1,,Cl,,test
US04902801,CCOC(=O)[C@@H]1C(=O)NC(=O)C[C@H]1c1ccc(F)cc1>>OC[C@@H]1CNCC[C@H]1c1ccc(F)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04446317,CC(C)CC(=O)OCBr.CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(COC(N)=O)CS[C@H]12)c1ccco1>>CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)OCOC(=O)CC(C)C)=C(COC(N)=O)CS[C@H]12)c1ccco1,,CN(C)C=O,,[K],,test
US04929269,COc1c(N)cc(C(C)(C)C)cc1S(=O)(=O)NC(C)(C)C.O=C(Cl)CCl>>COc1c(NC(=O)CCl)cc(C(C)(C)C)cc1S(=O)(=O)NC(C)(C)C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04853392,CCCc1ncc[nH]1.CCOC(=O)C(C)Br>>CCCc1nccn1C(C)C(=O)OCC,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20160159783A1,C[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1nc2cc(Cl)cc(C(=O)O)c2o1.O=C(O)C(F)(F)F>>C[C@H]1CNCCN1c1nc2cc(Cl)cc(C(=O)O)c2o1.O=C([O-])C(F)(F)F,,ClCCl,,CC(C)=O,,test
US20120108619A1,CCOC(=O)c1ccc2c(NC)nccc2c1>>CNc1nccc2cc(C(=O)O)ccc12,,CCO,,[K+].[OH-],,test
US05045552,COCCCOc1ccnc(CSc2nc3ccccc3s2)c1C.O=C(OO)c1cccc(Cl)c1>>COCCCOc1ccnc(CS(=O)c2nc3ccccc3s2)c1C,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20160221945A1,CC(C)(C)OC(=O)N1CC[C@@H](O)[C@H]1C(=O)NCc1ccc(F)c(-c2cnc(C(F)(F)F)cn2)c1.CCN(CC)S(F)(F)F>>CC(C)(C)OC(=O)N1CC[C@H](F)[C@H]1C(=O)NCc1ccc(F)c(-c2cnc(C(F)(F)F)cn2)c1,,ClCCl,,,,test
US20120101127A1,C=C(C)C.Cc1ccc(N=Cc2ccccc2[N+](=O)[O-])cc1>>Cc1ccc2c(c1)C(C)(C)CC(c1ccccc1[N+](=O)[O-])N2,,CC#N,,CCOCC,FB(F)F,test
US20140206856A1,COc1ccc(C(Cl)(c2ccccc2)c2ccc(OC)cc2)cc1.N#CCCOCOCO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1ccc(=O)[nH]c1=O>>COc1ccc(C(OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)[C@H](OCOCOCCC#N)[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1,,ClCCl,,c1ccncc1,,test
US20090298834A1,CC(C)(C)[C@H](O)C(=O)O.N[C@H]1CC[C@@H](CC(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1>>CC(C)(C)[C@H](O)C(=O)N[C@@H]1CC[C@H](CC(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1,,CCOC(C)=O,CN(C)C=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US05071859,CCOC(=O)[C@@H]1CCCN(CCO/C=C(/c2cccc(F)c2)c2ccccc2C)C1.Cl>>Cc1ccccc1/C(=C\OCCN1CCC[C@@H](C(=O)O)C1)c1cccc(F)c1.Cl,,CCO,,ClCCl,[Na+].[OH-],test
US04837319,Cc1nc(Cc2ccccc2)c(=O)n(CCO)c1C.O=S(Cl)Cl>>Cc1nc(Cc2ccccc2)c(=O)n(CCCl)c1C,,ClC(Cl)Cl,,,,test
US20110301142A1,CCOC(=O)c1cnn(Cc2ccc(-c3onc(C)c3NC(=O)OC(C)c3ccccc3Cl)cc2)c1>>Cc1noc(-c2ccc(Cn3cc(C(=O)O)cn3)cc2)c1NC(=O)OC(C)c1ccccc1Cl,,O,,C1CCOC1,[Li+].[OH-],test
US20140155389A1,COc1cc(N2CCN3CCCC3C2)ccc1[N+](=O)[O-]>>COc1cc(N2CCN3CCCC3C2)ccc1N,[Ni],CO,,,,test
US05281722,NC(c1ccccc1)c1ccccc1.O=C(O)CCCC[C@@H]1CCSS1>>NC(c1ccccc1)c1ccccc1.O=C(O)CCCC[C@@H]1CCSS1,,CCOCC,,,,test
US06313094B1,CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O.CCN(CC)CC.CN(C)C=O>>CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)NC(C)(C)C(N)=O,,CCN(CC)CC,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US20150011546A1,COc1nc(C)cc(OC(F)F)c1CNC(=O)OC(C)(C)C>>Cc1cc(OC(F)F)c(CN)c(=O)[nH]1,,Cl,,,,test
US20160068535A1,COc1cc(C2CCN(C(=O)OC(C)(C)C)CC2F)ccc1[N+](=O)[O-]>>COc1cc(C2CCN(C(=O)OC(C)(C)C)CC2F)ccc1N,[Pd],CO,,,,test
US03939267,CC(=O)Nc1ccc(O)cc1.NS(=O)(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1Cl>>CC(=O)Nc1ccc(Oc2c([N+](=O)[O-])cc(C(=O)O)cc2S(N)(=O)=O)cc1,,O=C([O-])O,[Na+],Cl,,test
US20060111375A1,COc1cc2nccc(Cl)c2cc1OC.Cc1cc(O)c(C(=O)c2ccccc2)cc1Cl>>COc1cc2nccc(Oc3cc(C)c(Cl)cc3C(=O)c3ccccc3)c2cc1OC,CN(C)c1ccncc1,Clc1ccccc1Cl,,,,test
US03932318,CCCCCCN=C=O.O=C=Nc1ccc(Cl)cc1.O=CC(Cl)(Cl)Cl>>CCCCCCN=C=O.O=C=Nc1ccc(Cl)cc1.O=CC(Cl)(Cl)Cl,,c1ccccc1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20130072473A1,CC(C)(C)OC(=O)N1CCc2c(sc(N)c2-c2nc3ccccc3s2)C1.CC=O>>CCNc1sc2c(c1-c1nc3ccccc3s1)CCN(C(=O)OC(C)(C)C)C2,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05498732,CC(C)=O.CC(C)C[C@H]1[C@@H](O)CC(=O)N1C(=O)OC(C)(C)C>>CC(C)C[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)O,,CC(C)=O,,Cl,[Na+].[OH-],test
US20160263122A1,CSc1ccc(C(=O)Nc2ccc(-c3ccccc3F)nc2)cc1NC(=O)CN1CCOCC1.O=S([O-])OO>>CS(=O)(=O)c1ccc(C(=O)Nc2ccc(-c3ccccc3F)nc2)cc1NC(=O)CN1CCOCC1,,CO,,O,,test
US20150018309A1,CC(O)(c1ccc(C#N)cc1)C(F)(F)F>>CC(O)(c1ccc(CN)cc1)C(F)(F)F,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090215821A1,COCCOS(=O)(=O)c1ccc(C)cc1.O=Cc1ccc(O)cc1>>COCCOc1ccc(C=O)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20060276515A1,Nc1ccccn1.O=C(O)CCC(c1ccccc1)c1ccccc1>>O=C(CCC(c1ccccc1)c1ccccc1)Nc1ccccn1,,CCN(CC)CC,ClCCl,ClCCCl,On1nnc2ccccc21,test
US20120059000A1,C[C@H](Nc1ncnc2[nH]cnc12)c1cc2cccc(C=O)c2c(=O)n1-c1ccccc1.NO>>C[C@H](Nc1ncnc2[nH]cnc12)c1cc2cccc(C#N)c2c(=O)n1-c1ccccc1,,CN1CCCC1=O,,Cl,,test
US20080312226A1,Fc1ccccc1-c1csc(N2CCNCC2)n1.O=C(Nc1cccnn1)OCC(Cl)(Cl)Cl>>O=C(Nc1cccnn1)N1CCN(c2nc(-c3ccccc3F)cs2)CC1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20050154042A1,COC(=O)C[C@H]1C[C@@H](CCc2c(-c3ccc(F)cc3)c(-c3ccccc3)c(C(=O)NCc3ccccc3)n2C(C)C)OC(C)(C)O1>>COC(=O)C[C@H](O)C[C@H](O)CCc1c(-c2ccc(F)cc2)c(-c2ccccc2)c(C(=O)NCc2ccccc2)n1C(C)C,,CCOC(C)=O,CO,Cl,,test
US20140371199A1,CC(=O)Nc1cc(Br)ccc1C(=O)N1CCN(C(=O)OC(C)(C)C)CC1.CC1(C)OB(c2ccc3ncc(-c4ccc(C#N)cc4)n3c2)OC1(C)C>>CC(=O)Nc1cc(-c2ccc3ncc(-c4ccc(C#N)cc4)n3c2)ccc1C(=O)N1CCN(C(=O)OC(C)(C)C)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20120088748A1,CC(C)(C)OC(=O)N1CCO[C@H](CI)[C@H](c2ccc(Cl)c(Cl)c2)C1.COC(=O)C1CCNCC1>>COC(=O)C1CCN(C[C@H]2OCCN(C(=O)OC(C)(C)C)C[C@H]2c2ccc(Cl)c(Cl)c2)CC1,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20060046999A1,COc1ccc(N)c(C)c1.N=C(CC(=O)c1ccccc1)Sc1ccccc1>>COc1ccc(NC(=N)CC(=O)c2ccccc2)c(C)c1,,CC(=O)O,,Cl,,test
US05405829,Cn1nc(C(N)=O)cc1OC(F)F.O=S(=O)(Cl)Cl>>Cn1nc(C(N)=O)c(Cl)c1OC(F)F,,CC#N,,,,test
US20100016350A1,CC(=O)O.CCOC1(O[Si](C)(C)C)CC1.N[C@@H]1CCN(c2ccc(Br)cn2)C1>>Brc1ccc(N2CC[C@@H](N(C3CC3)C3CC3)C2)nc1,,CO,,[BH3-]C#N.[Na+],,test
US20090186879A1,CC[Mg]Br.Cc1cc(N(C)C)ncc1N1CCCn2c1nc1c(Cl)ccc(C=O)c12>>CCC(O)c1ccc(Cl)c2nc3n(c12)CCCN3c1cnc(N(C)C)cc1C,,C1CCOC1,,,,test
US04734429,CN(C)C=C1C(=O)CCc2c1cnn2C.NN>>Cn1ncc2c1CCc1[nH]ncc1-2,,CO,,C,,test
US06251911B1,C1CCOC1.CC(C)COC(=O)Cl.CN1CCOCC1.Nc1n[nH]c2ncnc(Nc3cccc(Cl)c3)c12>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1n[nH]c2ncnc(Nc3cccc(Cl)c3)c12,,C1CCOC1,,,,test
US20060205969A1,CC(C)c1cccc(C(C)C)c1OC(=O)OC[C@H](N)C(=O)O>>CC(C)c1cccc(C(C)C)c1OC(=O)OC[C@H](N)C(=O)O,,CC#N,O,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US05055221,CCCCCCCCc1ccc(-c2ncc(O)cn2)cc1.CCCCCCCc1ccc(C(=O)Cl)cc1>>CCCCCCCCc1ccc(-c2ncc(OC(=O)c3ccc(CCCCCCC)cc3)cn2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110195954A1,COc1ccc2c(c1)CCN(C1CCN(c3cc(C(=O)O)ncn3)CC1)C(=O)N2.OCC1CNc2ccccc21>>COc1ccc2c(c1)CCN(C1CCN(c3cc(C(=O)N4CC(CO)c5ccccc54)ncn3)CC1)C(=O)N2,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,test
US20090111983A1,CCCN1CCN(c2ccc(C(=O)NC3(C(=O)OC)CCCCC3)cc2)CC1.Cl>>CCCN1CCN(c2ccc(C(=O)NC3(C(=O)OC)CCCCC3)cc2)CC1.Cl,,CCOC(C)=O,,,,test
US20110021771A1,COC(=O)CS.O=C(c1ccccc1)c1ccccc1F>>COC(=O)c1sc2ccccc2c1-c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090137580A1,Cn1c(C#N)cc2ncnc(Oc3ccc(N)c(Cl)c3)c21.O=C=Nc1cccc(C(F)(F)F)c1>>Cn1c(C#N)cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(Cl)c3)c21,,C1CCOC1,,CCN(CC)CC,,test
US20130190314A1,Cc1cc(-c2nc3ccc(N4CCN(C=O)CC4)nn3c2I)c(C)s1.Cc1cc(B(O)O)ccn1>>Cc1cc(-c2c(-c3cc(C)sc3C)nc3ccc(N4CCN(C=O)CC4)nn23)ccn1,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130116243A1,CN1C(=O)COc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccsc3)cc21>>CN1C(=O)COc2nc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccsc3)cc21,,ClCCl,,CO,,test
US20080090856A1,CCOC(=O)c1cc(Cl)ccc1I.OB(O)c1ccc2ncccc2c1>>CCOC(=O)c1cc(Cl)ccc1-c1ccc2ncccc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20050070592A1,Cc1c(C)n(Cc2ccccc2)c2ccc(-c3ccc(OCC#N)cc3)cc12.[N-]=[N+]=[N-]>>Cc1c(C)n(Cc2ccccc2)c2ccc(-c3ccc(OCc4nnn[nH]4)cc3)cc12,,CN(C)C=O,,[Cl-].[NH4+],,test
US20070010671A1,CNC.Cc1ccc2nc(Cl)nc(Cl)c2c1>>Cc1ccc2nc(Cl)nc(N(C)C)c2c1,,ClCCl,,,,test
US20100137313A1,COCCCNc1nc(Nc2ccc(F)c(Cl)c2)ncc1-c1ccc2cc(C(=O)OC)n(C(=O)OC(C)(C)C)c2c1>>COCCCNc1nc(Nc2ccc(F)c(Cl)c2)ncc1-c1ccc2cc(C(=O)OC)[nH]c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100249068A1,CCOC(C)=O.COC1O[C@H](C(C)OC(=O)c2ccc([N+](=O)[O-])cc2)[C@@H](O)[C@H]1O.O=C(Cl)c1ccccc1.c1ccncc1>>COC1O[C@H](C(C)OC(=O)c2ccc([N+](=O)[O-])cc2)[C@@H](OC(=O)c2ccccc2)[C@]1(O)C(=O)c1ccccc1,CN(C)c1ccncc1,c1ccncc1,,,,test
US05877193,COCCl.Cc1ccc(S(=O)(=O)Nc2nc(-c3cccc(Br)c3)cs2)cc1>>COCN(c1nc(-c2cccc(Br)c2)cs1)S(=O)(=O)c1ccc(C)cc1,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20060270706A1,CCOC(=O)Cc1cc(/C=C2\CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)CCC2=O)nn1C(=O)OC(C)(C)C>>CCOC(=O)Cc1cc(/C=C2\CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)CCC2O)nn1C(=O)OC(C)(C)C,,CCO,,[BH4-].[Na+],,test
US20120165298A1,CC(c1ccccc1-c1ccc(Cl)cc1)N1CCC2(CC1)OCCO2>>CC(c1ccccc1-c1ccc(Cl)cc1)N1CCC(=O)CC1,,C1COCCO1,O,Cl,,test
US20150322076A1,CC(C)(C)OC(=O)CC(=O)O.COC(=O)c1ccc(N)c(OC)c1.O=C(O)C(F)(F)F.O=C(n1ccnc1)n1ccnc1>>COC(=O)c1ccc(NC(=O)CN)c(OC)c1.O=C(O)C(F)(F)F,,C1CCOC1,ClCCl,,,test
US20040106628A1,CC(C)(C)OC(=O)N1CCC(Nc2nc3nc(SCc4ccccc4)nc(Cl)c3s2)CC1.CC(C)C[C@@H](N)CO>>CC(C)C[C@H](CO)Nc1nc(SCc2ccccc2)nc2nc(NC3CCN(C(=O)OC(C)(C)C)CC3)sc12,,C1CCOC1,,,,test
US20150291514A1,CC(C)(C)OC(=O)c1cc(F)c(F)cc1F.Oc1cnc(F)c(Cl)c1>>CC(C)(C)OC(=O)c1cc(F)c(Oc2cnc(F)c(Cl)c2)cc1F,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080255078A1,CCCC(=O)c1cccc(O)c1.CCOC(=O)CBr>>CCCC(=O)c1cccc(OCC(=O)OCC)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140205537A1,CCOC(=N)C(C)(C)C.COC(CN)OC>>CC(C)(C)c1ncc[nH]1,,CO,,Cl,,test
US20090298807A1,CCCc1nc(C(=O)O)cs1.OCCc1cccc(CN2CCC3(CC2)CNCCO3)c1>>CCCc1nc(C(=O)N2CCOC3(CCN(Cc4cccc(CCO)c4)CC3)C2)cs1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140128360A1,C1CNC1.CS(=O)(=O)c1cc(F)cc(OCCBr)c1>>CS(=O)(=O)c1cc(F)cc(OCCN2CCC2)c1,,CC#N,,ClCCl,O=C([O-])[O-].[K+].[K+],test
US05534188,CCCCCCCCCCOc1cnc(-c2ccc(C#CCCCC(C)OC(C)=O)cc2)nc1>>CCCCCCCCCCOc1cnc(-c2ccc(CCCCCC(C)OC(C)=O)cc2)nc1,,ClC(Cl)Cl,,,,test
US20150210657A1,CCc1cnc2ccccc2n1>>CC[C@H]1CNc2ccccc2N1,,Cc1ccccc1,,,,test
US04939261,CC(C)(C)C(=O)OCOC(=O)[C@@H](Cc1ccccc1)C[C@H](Cc1ccccc1)C(=O)OCc1ccccc1>>CC(C)(C)C(=O)OCOC(=O)[C@@H](Cc1ccccc1)C[C@H](Cc1ccccc1)C(=O)O,[Pd],CCO,,,,test
US05597820,CC[C@@H]1Oc2cc(C(=O)OC)ccc2N(C(C)C)C1=O>>CC[C@@H]1Oc2cc(C(=O)O)ccc2N(C(C)C)C1=O,,Cl,,,,test
US20120101136A1,CC(C)N.CC(C)Oc1ccc(-c2nc(-c3ccc(OCCCCBr)cc3Cl)no2)cc1C#N>>CC(C)NCCCCOc1ccc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)c(Cl)c1,,C1CCOC1,,,,test
US20040235782A1,Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1.O=C(Cl)c1ccccc1>>Nc1nc2c(ncn2[C@]2(C(=O)c3ccccc3)O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1,CN(C)c1ccncc1,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20060148858A1,CCOC(=O)Cc1cn(-c2ccc(C(F)(F)F)cn2)nc1OCC>>CCOc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCO,,C1CCOC1,CCCCCC,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20120122905A1,CCOC(=O)Cc1ccc(OCc2ccccc2)cc1.CCOC(=O)OCC>>CCOC(=O)C(C(=O)OCC)c1ccc(OCc2ccccc2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20140194431A1,O=C(c1nc(CC2(c3ccc(Cl)cc3)CCCC2)nc(O)c1OCc1ccccc1)N(CCO)C1CC1>>O=C1c2c(OCc3ccccc3)c(=O)nc(CC3(c4ccc(Cl)cc4)CCCC3)n2CCN1C1CC1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030096788A1,CCC(=O)CNC(=O)[C@H]1O[C@@H](OC)[C@@H]2OC(C)(C)O[C@H]21>>CCc1cnc([C@H]2O[C@@H](OC)[C@@H]3OC(C)(C)O[C@@H]32)o1,,Cc1ccccc1,,O=P(Cl)(Cl)Cl,,test
US20070037794A1,O=[N+]([O-])c1cc(Cl)cnc1Br.Oc1ccc(F)cc1>>O=[N+]([O-])c1cc(Cl)cnc1Oc1ccc(F)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100197591A1,COC(=O)Cc1ccc(Br)cc1.ICCCCCI>>COC(=O)C1(c2ccc(Br)cc2)CCCCC1,,C1CCOC1,,[H-].[Na+],,test
US20080027122A1,Clc1cccc2c1CCN2.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>OC[C@H]1O[C@@H](N2CCc3c(Cl)cccc32)[C@H](O)[C@@H](O)[C@@H]1O,,CCO,,O,,test
US20140142083A1,Cc1cc(C)c(CNC(=O)c2cc(C3=CCN(C)CC3)cc(N(C)C3CCCC3)c2C)c(=O)[nH]1>>Cc1cc(C)c(CNC(=O)c2cc(C3CCN(C)CC3)cc(N(C)C3CCCC3)c2C)c(=O)[nH]1,[Pd],CCO,,,,test
US20040030137A1,COCc1cc(Br)c(C(=O)C2CCN(C(=O)OC(C)(C)C)CC2)s1.NO>>COCc1cc(Br)c(C(=NO)C2CCN(C(=O)OC(C)(C)C)CC2)s1,,c1ccncc1,,Cl,Cl,test
US20020045615A1,COc1cccc2sc(N)nc12.O=C=NCc1ccccc1>>COc1cccc2sc(NC(=O)NCc3ccccc3)nc12,,C1CCOC1,,,,test
US20010006969A1,CC(C)(C)CN.Cc1csc2c(Cl)nc(Cl)nc12>>Cc1csc2c(NCC(C)(C)C)nc(Cl)nc12,,CN(C)C=O,,O,,test
US20080234255A1,CC1CN(Cc2ccccc2)c2nc(Cl)ncc2NC1=O.CI>>CC1CN(Cc2ccccc2)c2nc(Cl)ncc2N(C)C1=O,,CN(C)C=O,,[H-].[Na+],,test
US20150183781A1,CC(C)(C)OC(=O)N1CCC(n2cc(-c3cnc4[nH]cc(-c5cnn(Cc6cc(F)cc(F)c6)c5)c4c3)cn2)CC1.Cl>>Cl.Fc1cc(F)cc(Cn2cc(-c3c[nH]c4ncc(-c5cnn(C6CCNCC6)c5)cc34)cn2)c1,,C1COCCO1,CO,CCOCC,,test
US20090029988A1,COCCc1nc2c(N)nc3ccccc3c2n1CCCNC(=O)OC(C)(C)C>>COCCc1nc2c(N)nc3ccccc3c2n1CCCN,,C1COCCO1,,Cl,,test
US20090197959A1,CCNCc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)OC)ccc1OC.O=C(Cl)OCc1ccccc1Cl>>CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)OC)ccc1OC)C(=O)OCc1ccccc1Cl,,ClCCl,O,CCN(CC)CC,,test
US20060293322A1,Fc1ccc(Nc2ncnc3sc4c(c23)CCC2(C4)OCCO2)cc1Cl>>O=C1CCc2c(sc3ncnc(Nc4ccc(F)c(Cl)c4)c23)C1,,CC(=O)O,O,,,test
US20100331297A1,CC(C)(C)n1nc(Br)c2c(Nc3ncccn3)ncnc21.Cc1ccc(B(O)O)cc1>>Cc1ccc(-c2nn(C(C)(C)C)c3ncnc(Nc4ncccn4)c23)cc1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20030045523A1,O=C1C(=Cc2cccc([N+](=O)[O-])c2)N2CCC1CC2>>O=[N+]([O-])c1cccc(C=C2C(O)C3CCN2CC3)c1,,CO,,[BH4-].[Na+],,test
US03950339,N#CCSc1nc(Cl)cc(-c2ccccc2)n1.NCc1ccc2c(c1)OCO2>>N#CCSc1nc(NCc2ccc3c(c2)OCO3)cc(-c2ccccc2)n1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20100331295A1,CC(C)(O)c1cc(-c2ccc(-c3cccc(S(C)(=O)=O)c3)s2)n(-c2ccccc2F)n1.O=C1CCC(=O)N1Cl>>CC(C)(O)c1nn(-c2ccccc2F)c(-c2ccc(-c3cccc(S(C)(=O)=O)c3)s2)c1Cl,,CC#N,,,,test
US20080214529A1,COC(=O)C1(N(C)N=CCC(C)(C)C)CCCC1>>COC(=O)C1(N(C)NCCC(C)(C)C)CCCC1,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US20040259957A1,CCCOc1ccc(C=O)cc1.COc1cc(OC)cc(C(C)=O)c1>>CCCOc1ccc(/C=C/C(=O)c2cc(OC)cc(OC)c2)cc1,,CO,,[Na+].[OH-],,test
US20070167430A1,CC(C)(C)OC(=O)N1CCC(C(=O)NNC(=O)CCl)CC1>>CC(C)(C)OC(=O)N1CCC(c2nnc(CCl)o2)CC1,,ClCCl,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,c1ccncc1,test
US20090215750A1,CC1(C(=O)c2c[nH]c3ncc(-c4cn(S(=O)(=O)c5ccccc5)c5ccccc45)nc23)CCCCC1>>CC1(C(=O)c2c[nH]c3ncc(-c4c[nH]c5ccccc45)nc23)CCCCC1,,ClCCl,,,,test
US20130029962A1,COCCN(C)c1ccc(C(C)C(=O)NCc2cc(C(F)(F)F)nn2-c2cccc(Cl)c2)cn1>>CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)c1ccc(N(C)CCO)nc1,,ClCCl,O,BrB(Br)Br,O=C([O-])O.[Na+],test
US20070155839A1,CCOC(=O)/C=C/c1ccc(C(=C2CCCCCC2)c2ccc(O)c(F)c2)cc1>>O=C(O)/C=C/c1ccc(C(=C2CCCCCC2)c2ccc(O)c(F)c2)cc1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20120046292A1,CCOC(=O)[C@H]1CC[C@@H](Oc2ccc(C(=O)OCc3ccccc3)cc2)CC1>>CCOC(=O)[C@@H]1CC[C@H](Oc2ccc(C(=O)O)cc2)CC1,[Pd],CCO,,,,test
US20140349972A1,C#Cc1cnc(-c2ccccn2)nc1OCc1ccc(OC)cc1.COC(=O)c1ccc(C(Cl)=NO)cc1>>COC(=O)c1ccc(-c2cc(-c3cnc(-c4ccccn4)nc3OCc3ccc(OC)cc3)on2)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20140221361A1,C=C(CN(CCN(C)C)C(=O)OC(C)(C)C)[C@@H]1CC[C@]2(C(=O)NCCC(=O)OCC)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC(C)(C)C)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(CN(CCN(C)C)C(=O)OC(C)(C)C)[C@@H]1CC[C@]2(C(=O)NCCC(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC(C)(C)C)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1COCCO1,,[Na+].[OH-],,test
US20040122050A1,CC(=O)OC(C)=O.OC1CN(C(c2ccccc2)c2ccccc2)C1>>CC(=O)OC1CN(C(c2ccccc2)c2ccccc2)C1,CN(C)c1ccccn1,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20030236250A1,O=C1CN(Cc2ccccc2)CCN1c1cccc(Cl)n1>>O=C1CNCCN1c1cccc(Cl)n1,,ClCCl,,CC(Cl)OC(=O)Cl,,test
US20070060587A1,CCOC(=S)c1ccccc1.[C-]#[N+]CC(=O)OCC>>CCOC(=O)c1ncsc1-c1ccccc1,,CCO,,[C-]#N.[Na+],,test
US20060217372A1,CCOC(=O)c1ccc(Oc2ccc(CN(CCc3ccccc3)C(=O)OC(C)(C)C)cc2)nc1>>CC(C)(C)OC(=O)N(CCc1ccccc1)Cc1ccc(Oc2ccc(C(=O)O)cn2)cc1,,C1CCOC1,,CO,[Na+].[OH-],test
US05037834,CC(=O)N1CCc2nc(N)sc2C1>>Nc1nc2c(s1)CNCC2,,CCO,,[Na+].[OH-],[Cl-].[NH4+],test
US20130210801A1,C1COCCN1.Cc1cc2nc(OS(=O)(=O)C(F)(F)F)ccc2c(-c2ccc(Cl)cc2)c1[C@@H](COC(=O)C(C)(C)C)OC(C)(C)C>>Cc1cc2nc(N3CCOCC3)ccc2c(-c2ccc(Cl)cc2)c1[C@@H](COC(=O)C(C)(C)C)OC(C)(C)C,,COCCOC,,,,test
US06093732,COc1c(F)cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(COCC[Si](C)(C)C)c2c1F>>COc1c(F)cc2c(O)c(C(=O)NCc3ccc(Cl)cc3)cnc2c1F,,CCO,,Cl,O=C([O-])O.[Na+],test
US20130230458A1,CCC(C)OC(=O)[C@@H](N)CCCNC(=O)OCc1ccccc1.Cc1ccc(S(=O)(=O)Cl)cc1>>CCC(C)OC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(C)cc1,,CC(C)=O,CCOC(C)=O,Cl,O=C([O-])O.[Na+],test
US20100041676A1,N#Cc1[nH]ncc1[N+](=O)[O-].N=CN>>Nc1ncnc2cn[nH]c12,[Pd],CCO,,CC(=O)O,,test
US08518916B2,BrC(Br)(Br)Br.C#CC=C1CCN(c2ncccc2[N+](=O)[O-])CC1>>O=[N+]([O-])c1cccnc1N1CCC(=CC#CBr)CC1,,c1ccccc1,,[K+].[OH-],,test
US20110105533A1,CC(C)S(=O)(=O)N[C@@H]1COC[C@H]1OS(C)(=O)=O.Oc1ccc(Br)cc1>>CC(C)S(=O)(=O)N[C@@H]1COC[C@H]1Oc1ccc(Br)cc1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],O=C([O-])O.[Na+],test
US05541195,O=C([C@@H]1Cc2c([nH]c3ccccc23)CN1C(=O)OCC1c2ccccc2-c2ccccc21)N1CC[C@H](N(Cc2ccnc3ccccc23)C(=O)C(F)(F)F)C[C@H]1Cc1ccccc1>>O=C([C@@H]1Cc2c([nH]c3ccccc23)CN1)N1CC[C@H](N(Cc2ccnc3ccccc23)C(=O)C(F)(F)F)C[C@H]1Cc1ccccc1,,CN(C)C=O,,C1CCNCC1,,test
US20070060592A1,CC(C)(O)c1ccc2c(c1)C(=CCCN1CCN(c3ccc(Cl)cc3)C(C#N)C1)c1cccnc1CO2.CO>>CC(C)(O)c1ccc2c(c1)C(=CCCN1CCN(c3ccc(Cl)cc3)C(C(N)=O)C1)c1cccnc1CO2,,C1CCOC1,CO,[Na+].[OH-],,test
US20100137362A1,Nc1ccc(Cl)nc1I.OB(O)c1ccco1>>Nc1ccc(Cl)nc1-c1ccco1,,C1CCOC1,O,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20100063120A1,CC(=O)OCC#CCN1C(=O)N(c2ccc(Cl)c(Cl)c2)C(=O)C1(C)c1ccc(O)cc1>>CC1(c2ccc(O)cc2)C(=O)N(c2ccc(Cl)c(Cl)c2)C(=O)N1CC#CCO,,CCO,Cl,,,test
US06159715,CCO.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>CCO.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO,,CCO,,,,test
US20110053990A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN(CCN)CCN>>CN(CCN)CCNC(=O)OC(C)(C)C,,ClCCl,,,,test
US04894386,CCCCNC(=O)Cc1ccc2c(ccn2C)c1.COC(=O)c1ccc(CBr)c(OC)c1>>CCCCNC(=O)Cc1ccc2c(c1)c(Cc1ccc(C(=O)OC)cc1OC)cn2C,,CN(C)C=O,,,,test
US20040122050A1,O=C(CC1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1)c1ccc(CO)o1>>O=Cc1ccc(C(=O)CC2CCC(c3cc(F)ccc3F)(S(=O)(=O)c3ccc(Cl)cc3)CC2)o1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04634704,CC(=O)CCl.NC(=S)NCCN1CCC(Nc2nc3ccccc3n2Cc2ccc(F)cc2)CC1>>Cc1csc(NCCN2CCC(Nc3nc4ccccc4n3Cc3ccc(F)cc3)CC2)n1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20120270938A1,CCCN.COCOc1c(C)cc(/C=C/c2cccc(C(=O)O)c2)cc1C>>CCCNC(=O)c1cccc(/C=C/c2cc(C)c(O)c(C)c2)c1,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,ClCCCl,On1nnc2cccnc21,test
US20100130695A1,CCCCCCCCCCCCCCCCCCO.O=C(O)C(=O)c1ccccc1>>CCCCCCCCCCCCCCCCCCOC(=O)C(=O)c1ccccc1,,O,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US20100324284A1,CS(N)(=O)=O.ClCCc1c(Cl)nc(N2CCOCC2)nc1Cl>>CS(=O)(=O)N1CCc2c(Cl)nc(N3CCOCC3)nc21,,CN1CCCC1=O,,O,O=C([O-])[O-].[K+].[K+],test
US20020137664A1,CCOC(=O)C1(C2=CCOCC2)CCNCC1.Cl>>CCOC(=O)C1(C2CCOCC2)CCNCC1.Cl,O=[Pt],CCO,,,,test
US20120108582A1,C=CC[C@]1(C(=O)OC(C)(C)C)CC(=O)N([C@H](C)c2ccccc2)C1.O=[O+][O-]>>C[C@H](c1ccccc1)N1C[C@@](CC=O)(C(=O)OC(C)(C)C)CC1=O,,CO,,,,test
US20150203511A1,COc1ccc(-c2nn(C)c(Cl)c2C)cc1C>>Cc1cc(-c2nn(C)c(Cl)c2C)ccc1O,,CC(=O)O,,Br,,test
US20160272628A1,CC(=O)OC(C)=O.OCCCc1cccc(Br)c1>>CC(=O)OCCCc1cccc(Br)c1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20100216746A1,CCOC(=O)c1[nH]c2ccc(OCCO[Si](C)(C)C(C)(C)C)cc2c1Br>>O=C(O)c1[nH]c2ccc(OCCO)cc2c1Br,,C1CCOC1,CO,[Li+].[OH-],,test
US20100190782A1,COC(=O)c1nc(Br)ccc1O>>O=C(O)c1nc(Br)ccc1O,,CO,,[Li+].[OH-],,test
US20110237791A1,COc1ccc(CN2C(=O)CC[C@@H]2/C=C(\c2ccc(C(C)(C)C)cc2)c2ccc(CCC(=O)O)c(=O)[nH]2)c(OC)c1.N>>COc1ccc(CN2C(=O)CC[C@@H]2/C=C(\c2ccc(C(C)(C)C)cc2)c2ccc(CCC(N)=O)c(=O)[nH]2)c(OC)c1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20120252779A1,BrP(Br)Br.CC(C)(C)OC(=O)N1CCN(c2cc(F)c(F)c(CO)c2F)CC1>>CC(C)(C)OC(=O)N1CCN(c2cc(F)c(F)c(CBr)c2F)CC1,,ClCCl,,,,test
US20120202834A1,CCCC(Nc1ccc(-n2cc(C(F)(F)F)cn2)cc1)c1ccc(C(=O)NCCC(=O)OCC)cc1>>CCCC(Nc1ccc(-n2cc(C(F)(F)F)cn2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1,,CO,,C1CCOC1,[Li+].[OH-],test
US06166006,CI.O=C(Nc1ccc(CN2CCCCC2)cc1)C1=Cc2cc(-c3ccccc3)ccc2CC1>>C[N+]1(Cc2ccc(NC(=O)C3=Cc4cc(-c5ccccc5)ccc4CC3)cc2)CCCCC1.[I-],,CN(C)C=O,,,,test
US20090042892A1,C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1nccnc1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1nccnc1OS(=O)(=O)C(F)(F)F,,ClCCl,,Cc1cccc(C)n1,,test
US20050227995A1,C[C@H](CO)[C@@H](c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1.N#Cc1ccc(N=C=O)cc1>>C[C@H](COC(=O)Nc1ccc(C#N)cc1)[C@@H](c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1,,C1CCOC1,,,,test
US20020120011A1,COCc1cccc([N+](=O)[O-])c1>>COCc1cccc(N)c1,[Zn],CC(=O)O,,,,test
US20040152697A1,CCC(=O)CN([C@H]1CCN([C@@H](C)C(=O)OC(C)(C)C)C1=O)S(=O)(=O)c1ccc2cc(Cl)ccc2c1>>CCC(=O)CN([C@H]1CCN([C@@H](C)C(=O)O)C1=O)S(=O)(=O)c1ccc2cc(Cl)ccc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070173507A1,CCI.O=c1[nH]ccc2cc(Br)ccc12>>CCn1ccc2cc(Br)ccc2c1=O,,O,,CN(C)C=O,[H-].[Na+],test
US20130018030A1,CCc1cnc(Cl)nc1.C[C@@]1(C2CCNCC2)Cc2cc(C3=CCN(S(C)(=O)=O)CC3)ncc2O1>>CCc1cnc(N2CCC([C@]3(C)Cc4cc(C5=CCN(S(C)(=O)=O)CC5)ncc4O3)CC2)nc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050107357A1,COC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1[N+](=O)[O-]>>COC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1N,[Pd],CCOC(C)=O,,,,test
US20130085151A1,CC(=O)c1cc2cc(Cl)sc2nc1Cl>>C[C@@H](O)c1cc2cc(Cl)sc2nc1Cl,,C1CCOC1,,,,test
US20050096343A1,CC(=O)NC[C@H]1CN(c2ccc(N3CCNCC3)c(F)c2)C(=O)O1.CC(C)(C)OC(=O)N1CCNCC1.O=C(Br)CBr>>CC(=O)NC[C@H]1CN(c2ccc(N3CCN(C(=O)CN4CCN(C(=O)OC(C)(C)C)CC4)CC3)c(F)c2)C(=O)O1,,ClCCl,,CCN(CC)CC,O=C([O-])[O-].[K+].[K+],test
US06239151B1,CC(=O)OC(C)=O.OC/C=C/CC1CCCCC1>>CC(=O)OC/C=C/CC1CCCCC1,CN(C)c1ccncc1,CCOCC,,CCN(CC)CC,,test
US20090192156A1,CC(C)(C)OC(=O)N1CCC(OCCN2CCCCC2)CC1>>C1CCN(CCOC2CCNCC2)CC1,,C1COCCO1,CO,Cl,,test
US06328793B1,CO.O=C(O)c1ccccc1C(=O)c1ccccc1>>COC(=O)c1ccccc1C(=O)c1ccccc1,Cc1ccc(S(=O)(=O)O)cc1,,,,,test
US20110028494A1,COC(=O)[C@@H]1C[C@@H](Oc2ncnc3ccc(Br)cc23)CN1C(=O)OC(C)(C)C.Cl>>COC(=O)[C@@H]1C[C@@H](Oc2ncnc3ccc(Br)cc23)CN1.Cl,,C1COCCO1,,,,test
US20090042967A1,CCOC(=O)C(C)(C)C(=O)[C@H](C)NC(=O)OCc1ccccc1>>CCOC(=O)C(C)(C)C(O)[C@H](C)NC(=O)OCc1ccccc1,,CO,,[BH4-].[Na+],[Cl-].[NH4+],test
US20070244092A1,CCC(C)(C)c1nc2cc(S(=O)(=O)Cl)ccc2n1CC1CCOCC1.CCNC(=O)c1cc[nH]c1>>CCNC(=O)c1ccn(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)CC)n3CC2CCOCC2)c1,,C1CCOC1,,[H-].[Na+],,test
US20090149651A1,NC(N)=S.O=[N+]([O-])c1ccc(CBr)cc1.[Br-]>>Br.N=C(N)SCc1ccc([N+](=O)[O-])cc1,,CC(C)=O,,,,test
US20090176732A1,CCOC(=O)C1(C(=O)OCC)COC(C)(OCC)OC1>>CCOC(=O)C(CO)(COC(C)=O)C(=O)OCC,,CC(=O)O,,,,test
US20060217382A1,COc1cc(Nc2ncc(C(C)NC(=O)c3ccccc3NC(=O)C(C)(C)C)nn2)cc(OC)c1OC>>COc1cc(Nc2ncc3c(C)nc(-c4ccccc4NC(=O)C(C)(C)C)n3n2)cc(OC)c1OC,,ClCCCl,,O=P(Cl)(Cl)Cl,,test
US20080287396A1,CCOP(=O)(OCC)C(CCCI)P(=O)(OCC)OCC.COc1c(N2C[C@@H]3[C@@H](CCCN3C(=O)OC(C)(C)C)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12>>CCOP(=O)(OCC)C(CCCOC(=O)c1cn(C2CC2)c2c(OC)c(N3C[C@@H]4[C@@H](CCCN4C(=O)OC(C)(C)C)C3)c(F)cc2c1=O)P(=O)(OCC)OCC,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20130210806A1,CS(=O)(=O)Cl.FC(F)(F)c1c(CCc2ccccc2)cc2c3c1ccn3CCNC2>>CS(=O)(=O)C1Cn2ccc3c(C(F)(F)F)c(CCc4ccccc4)cc(c32)CN1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110160237A1,COC(=O)C(C)(C(=O)c1cn2c3c(cccc13)CCC2)c1cn(C(=O)OC(C)(C)C)c2ccccc12.NN>>O=c1[nH][nH]c(-c2cn3c4c(cccc24)CCC3)c1-c1c[nH]c2ccccc12,,CC(=O)O,,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US20070036743A1,NC1(Cl)C=C([N+](=O)[O-])C=C(Cl)C1O>>Nc1cc([N+](=O)[O-])cc(Cl)c1O,,CCO,,,,test
US05563147,Cn1c2c(c3ccccc31)CCN(C(=O)OC(C)(C)C)C2>>Cn1c2c(c3ccccc31)CCNC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100310466A1,O=C(CC(=O)C1CCOCC1)c1cccc(-c2ccccc2)c1O>>O=c1cc(C2CCOCC2)oc2c(-c3ccccc3)cccc12,Cl[Cu]Cl,CCO,,,,test
US04239901,CC(C(=O)O)c1ccc(-n2cc(N)cn2)c(Cl)c1.Cl[Cu]>>CC(C(=O)O)c1ccc(-n2cc(Cl)cn2)c(Cl)c1,Cl[Cu],,,Cl,O=N[O-].[Na+],test
US20110046378A1,CC(=O)Oc1ccc2c(c1)[nH]c1ccccc12.O=C1CCC(=O)N1Br>>CC(=O)Oc1ccc2c(c1)[nH]c1ccc(Br)cc12,,ClCCl,,,,test
US05811459,COC(=O)c1ccc(CCCc2cc(O)ccc2OCc2ccccc2)cc1.NC(=O)CBr>>NC(=O)COc1ccc(OCc2ccccc2)c(CCCc2ccc(C(=O)O)cc2)c1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120157383A1,N.O=C(N[C@H](Cc1ccc(-c2ccccc2)cc1)C[C@@H](O)C(=O)O)c1cnc(O)nc1>>NC(=O)[C@H](O)C[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)c1cnc(O)nc1,,C1COCCO1,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04281120,C1COCCN1.Nc1nnc(Br)s1>>Nc1nnc(N2CCOCC2)s1,,CCO,,,,test
US20050267095A1,BrCCOCCBr.NCC1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1>>c1cc(C2(CN3CCOCC3)CCOCC2)ccc1OCCCN1CCCC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US08129361B2,Cc1cc(CCCO)ccc1F.O=C1CCC(=O)N1Br>>Cc1cc(CCCBr)ccc1F,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04016166,CCNC(=O)c1ccccc1Nc1cccc([N+](=O)[O-])c1.CCOC(=O)Cl>>CCn1c(=O)c2ccccc2n(-c2cccc([N+](=O)[O-])c2)c1=O,,O,,C1CCOC1,[H-].[Na+],test
US20150210682A1,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OC)c(Cl)c1CC2C>>COc1cc2c(c(Cl)c1OC)CC(C)n1cc(C(=O)O)c(=O)cc1-2,,C1CCOC1,,Cl,[Na+].[OH-],test
US20130158112A1,N#Cc1cccc(CSCCNC(=O)c2c(Cl)cccc2Cl)c1.OO>>NC(=O)c1cccc(CSCCNC(=O)c2c(Cl)cccc2Cl)c1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070072853A1,CC(C)N=C=O.CN(c1ccc2c(c1)nc(C(F)(F)F)n2CC1CCOCC1)S(=O)(=O)c1ccc(N)cc1>>CC(C)NC(=O)Nc1ccc(S(=O)(=O)N(C)c2ccc3c(c2)nc(C(F)(F)F)n3CC2CCOCC2)cc1,,ClCCCl,,,,test
US20120263708A1,CS(=O)(=O)Cl.Nc1ccc(-c2ccc3ncc(N4CCOCC4)nc3c2)cc1>>CS(=O)(=O)Nc1ccc(-c2ccc3ncc(N4CCOCC4)nc3c2)cc1,,c1ccncc1,,,,test
US20050267095A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.ClCCl.NCC1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1>>CN(CC1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US05232923,COc1ccc(CCNC(C)=O)cc1OC>>CCNCCc1ccc(OC)c(OC)c1,,C1CCOC1,CCOC(C)=O,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20100166819A1,COC(=O)C1CCN(C(=O)OC(C)(C)C)CC1.COCCBr>>COCCC1(C(=O)OC)CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US06875884B1,BrCC1CO1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1CC1CO1,,CN(C)C=O,,O,[K],test
US20060247250A1,Cc1ccc(C(=O)O)cc1Br>>Cc1ccc(CO)cc1Br,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20050165065A1,BrC(c1ccccc1)c1ccccc1.CCOC(=O)[C@@H]1C[C@H](NC(=O)CC(c2ccccc2)c2ccccc2)CN1>>CCOC(=O)[C@@H]1C[C@H](NC(=O)CC(c2ccccc2)c2ccccc2)CN1C(c1ccccc1)c1ccccc1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070219235A1,Nc1cc(Cl)c(C(=O)Nc2ccc3cn[nH]c3c2)cc1[N+](=O)[O-]>>Nc1cc(Cl)c(C(=O)Nc2ccc3cn[nH]c3c2)cc1N,[Fe],CC(=O)O,CCO,,,test
US05869485,NCCO.Nc1ncnc2c1c(-c1ccccc1)cn2-c1cccc(C(=O)O)c1>>Nc1ncnc2c1c(-c1ccccc1)cn2-c1cccc(C(=O)NCCO)c1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US03952031,CC(=O)C1=CC[C@H]2[C@@H]3CC[C@H]4C[C@@H]5O[C@@H]5C[C@]4(C)[C@H]3C(=O)C[C@]12C.Cl>>CC(=O)C1=CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@@H](Cl)C[C@]4(C)[C@H]3C(=O)C[C@]12C,,ClC(Cl)Cl,,,,test
US20140378475A1,Cc1c(Br)cccc1NC(=O)c1cccc(Cl)c1N.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>Cc1c(Br)cccc1-n1c(=O)[nH]c2c(Cl)cccc2c1=O,,C1CCOC1,ClCCl,,,test
US20150111870A1,COc1c(CC(F)(F)F)c(Cl)nc2ccc(C(O)c3cnc(C)n3C)cc12.Cn1ccnn1>>COc1c(CC(F)(F)F)c(Cl)nc2ccc(C(O)(c3cnnn3C)c3cnc(C)n3C)cc12,,C1CCOC1,,[Li]CCCC,,test
US20110319380A1,O=CCC(F)(F)F.O=c1c2ccc(C#Cc3ccccn3)cc2nc2n1CCNCC2>>O=c1c2ccc(C#Cc3ccccn3)cc2nc2n1CCN(CCC(F)(F)F)CC2,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20020006925A1,CCN=C=O.CSc1ccc2c(c1)C(c1ccc(NC(C)=O)cc1)=NNC2C>>CCNC(=O)N1N=C(c2ccc(NC(C)=O)cc2)c2cc(SC)ccc2C1C,,ClC(Cl)Cl,,,,test
US06034275,C=CCNC.OC/C=C/CBr>>C=CCN(C)C/C=C/CO,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04511573,CCOC(=O)C(C)=Cc1ccc(CCl)cc1.c1cncc(-c2cc3ccccc3[nH]2)c1>>CCOC(=O)C(C)=Cc1ccc(Cc2c(-c3cccnc3)[nH]c3ccccc23)cc1,,C1CCOC1,,CC[Mg]Br,,test
US20110294776A1,CS(=O)(=O)Cl.Nc1ncnn2c(C3CCNC3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12>>CS(=O)(=O)N1CCC(c2cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c3c(N)ncnn23)C1,,C1CCOC1,,CCN(CC)CC,,test
US20030040533A1,CCOC(=O)C(Cc1ccc(OCCn2c(=O)oc3ccccc32)cc1)C(=O)OCC>>CCOC(=O)C(Cc1ccc(OCCn2c(=O)oc3ccccc32)cc1)C(=O)O,,CCO,,C1CCOC1,[Na+].[OH-],test
US20140256546A1,FC(F)(F)c1ccnc(Cl)c1.II>>Cc1ccnc(Cl)c1I,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US06602865B1,Cn1ncc2c(c1=O)SCCNC2.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>Cn1ncc2c(c1=O)SCCNC2C(=O)c1ccc([N+](=O)[O-])cc1,,O,,c1ccncc1,,test
US20070066639A1,O=P(Cl)(Cl)Cl.O=[N+]([O-])c1cnc2ccccc2c1O>>O=[N+]([O-])c1cnc2ccccc2c1Cl,,CN(C)C=O,,,,test
US20100305096A1,CC1(O)CNC1.Cn1c(CC=O)nc2c(N3CCOCC3)nc(Cl)nc21>>Cn1c(CCN2CC(C)(O)C2)nc2c(N3CCOCC3)nc(Cl)nc21,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04233299,COC1=C(C(=O)Nc2ncc(C)s2)N(C)S(=O)(=O)c2ccccc21>>Cc1cnc(NC(=O)C2=C(O)c3ccccc3S(=O)(=O)N2C)s1,,CC(=O)O,,Br,,test
US20030078239A1,CCOC(=O)C(C)(C)CCCCC1(CCCCC(C)(C)C(=O)OCC)SCCCS1>>CC(C)(CCCCC1(CCCCC(C)(C)C(=O)O)SCCCS1)C(=O)O,,CCO,O,Cl,[K+].[OH-],test
US20150299201A1,CC(=O)NN.S=C1CC=C(c2ccc(Cl)cc2)c2ccccc2N1>>Cc1nnc2n1-c1ccccc1C(c1ccc(Cl)cc1)=CC2,,CCCCO,,,,test
US04181722,CC(=O)C1=Cc2ccccc2OC1.CCO.CN1CCNCC1.Cl>>CN1CCN(CCC(=O)C2=Cc3ccccc3OC2)CC1.Cl,,Cl,,,,test
US20080300191A1,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF.CNC>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)NC(CC(=O)N(C)C)C(=O)CF,,C1CCOC1,CCOC(C)=O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20150329535A1,CC(C)(C)[Si](C)(C)O[C@@H](CNCCc1ccc(OCCCc2ccc(-c3ccccc3)c(NC(=O)O[C@H]3CN4CCC3CC4)c2)cc1)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12>>CC(C)(C)[Si](C)(C)O[C@@H](CNCCc1ccc(OCCCc2ccc(-c3ccccc3)c(NC(=O)O[C@H]3CN4CCC3CC4)c2)cc1)c1ccc(O)c2[nH]c(=O)ccc12,,CC(=O)O,,,,test
US20130296558A1,C#C[C@@H](C[C@H](O)C1CO1)O[Si](C)(C)C(C)(C)C.CC(=O)OC(C)=O>>C#C[C@@H](C[C@H](OC(C)=O)C1CO1)O[Si](C)(C)C(C)(C)C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,[Cl-].[NH4+],test
US20110183985A1,COC[C@H]1CCCN1c1c(C(C)=O)cc(Cl)c2cccnc12.[NH4+]>>COC[C@H]1CCCN1c1c(C(C)N)cc(Cl)c2cccnc12,,CC#N,CO,[BH3-]C#N.[Na+],,test
US20080306102A1,O=C(Br)CBr.O=C1Nc2ccccc2C12CCNCC2>>O=C(CBr)N1CCC2(CC1)C(=O)Nc1ccccc12,,ClCCl,O,CCN(CC)CC,CN(C)C=O,test
US20100234395A1,CC(C)(C)OC(=O)N1CCC(C(N)=S)CC1.COc1ccc(C(=O)C(Br)c2ccc(OC)cc2)cc1>>COc1ccc(-c2nc(C3CCNCC3)sc2-c2ccc(OC)cc2)cc1,,CO,,,,test
US20150166480A1,COC(=O)c1cnc(-c2ccc(OCC3CCN(CC(C)(C)F)CC3)cc2)cn1>>CC(C)(F)CN1CCC(COc2ccc(-c3cnc(C(=O)O)cn3)cc2)CC1,,C1CCOC1,,O,[Li]O,test
US20130244958A1,COc1cc(C(=O)OCOP(=O)(OC(C)(C)C)OC(C)(C)C)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F.O=C(O)C(F)(F)F>>COc1cc(C(=O)OCOP(=O)(O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20110263548A1,CSc1ncc(B2OC(C)(C)C(C)(C)O2)cn1.[O-]B1OO1>>CSc1ncc(O)cn1,,C1CCOC1,O,CCOC(C)=O,,test
US20070155721A1,CC(C)O.COC(=O)c1cc2c(O)cccc2[nH]1>>COC(=O)c1cc2c(OC(C)C)cccc2[nH]1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05516774,Cc1ccccc1C(=O)Nc1ccc(C(=O)Cl)cc1Cl.c1ccc2c(c1)Cn1cccc1CN2>>Cc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05977150,NNC(=O)c1ccc(C(F)(F)F)cc1.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]nc(-c2ccc(C(F)(F)F)cc2)o1,,C1CCOC1,,CCN(CC)CC,,test
US05693636,NO.O=C1CCCc2ccc([N+](=O)[O-])cc21>>O=[N+]([O-])c1ccc2c(c1)CC(=NO)CC2,,CO,,CC(=O)[O-].[Na+],,test
US20080090854A1,CC(=O)Oc1ccc(F)c2ccccc12>>Oc1ccc(F)c2ccccc12,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20060009602A1,C=C(C)C(=O)OCC(C)(O)C(F)(F)C(O)(O)C(F)(F)F>>C=C(C)C(=O)OCC(C)(O)C(F)(F)C(O)C(F)(F)F,,ClCCl,,Cl,,test
US20160137636A1,Cn1cc(Br)c2ccc(S(=O)(=O)Cl)cc21.Nc1ccon1>>Cn1cc(Br)c2ccc(S(=O)(=O)Nc3ccon3)cc21,,CCOC(C)=O,Cl,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20120232056A1,COC(=O)c1ccc2nc(-c3nc4ccccc4s3)c(N(C)C(C)C)nc2c1>>CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1nc2ccccc2s1,,CO,O,Cl,[Na+].[OH-],test
US20070191425A1,COC(=O)N1CCc2ccccc2[C@@H]1c1ccccc1.O[C@H]1CN2CCC1CC2>>O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1,,CN(C)C=O,Cc1ccccc1,C[O-].[Na+],,test
US20070232627A1,COC(=O)c1ccc(Cl)c([N+](=O)[O-])c1.COc1ccc(S)cc1>>COC(=O)c1ccc(Sc2ccc(OC)cc2)c([N+](=O)[O-])c1,,CN(C)C=O,,O,,test
US20010025033A1,C[Si](C)(C)C#Cc1c[nH]c(=O)[nH]c1=O>>C#Cc1c[nH]c(=O)[nH]c1=O,,CO,,Cl,C[O-].[Na+],test
US04472435,NO.O=C1CN=C(c2ccccc2)c2cc([N+](=O)[O-])ccc2N1>>NCC(=O)Nc1ccc([N+](=O)[O-])cc1C(=NO)c1ccccc1,,ClCCl,c1ccncc1,Cl,,test
US20030229082A1,BrCCCBr.Clc1ccc2c(c1)Nc1ccccc1S2>>Clc1ccc2c(c1)N(CCCBr)c1ccccc1S2,,CN(C)C=O,,[H-].[Na+],,test
US03941802,Nc1ccc(F)cc1C(=O)c1c(F)cccc1F>>Nc1ccc(F)cc1Cc1c(F)cccc1F,,OCCOCCO,,[K+].[OH-],,test
US20160237059A1,CSc1cccnc1-c1nc(C(F)(F)F)c(Oc2ccc(Cl)c(Cl)c2)c(=O)[nH]1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1cccnc1-c1nc(C(F)(F)F)c(Oc2ccc(Cl)c(Cl)c2)c(=O)[nH]1,,ClCCl,,,,test
US20080096861A1,CC(C)(C)OC(=O)N1CCNCC1.ClCCCI>>CC(C)(C)OC(=O)N1CCN(CCCCl)CC1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20090233904A1,COC(=O)C1CCCC2(CCCC2)C1=O.N=C(N)N>>Nc1nc(O)c2c(n1)C1(CCCC1)CCC2,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080300242A1,COc1cc(N2CCC(N3CCN(S(C)(=O)=O)CC3)CC2)ccc1N.O=C(Nc1c(F)cccc1F)c1cccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)c1>>COc1cc(N2CCC(N3CCN(S(C)(=O)=O)CC3)CC2)ccc1Nc1nccc(-c2c(-c3cccc(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05177096,CCCCc1nc(CO[Si](C)(C)C(C)(C)C)c(/C=C(\Cc2cccs2)C(=O)OCC)n1Cc1ccccc1Cl>>CCCCc1nc(CO[Si](C)(C)C(C)(C)C)c(/C=C(\Cc2cccs2)C(=O)O)n1Cc1ccccc1Cl,,CCO,,[Na+].[OH-],,test
US20080188528A1,CC(C)c1cccc(-c2ccccc2CO)c1.O=S(Cl)Cl>>CC(C)c1cccc(-c2ccccc2CCl)c1,,ClCCCl,,,,test
US20160102071A1,CC#C[C@@H](CC(=O)OCC)c1ccc(COc2ccc3scc(-c4ccc(OCC5CCS(=O)(=O)CC5)cc4C)c3c2)cc1>>CC#C[C@@H](CC(=O)O)c1ccc(COc2ccc3scc(-c4ccc(OCC5CCS(=O)(=O)CC5)cc4C)c3c2)cc1,,CCO,,Cl,[Li+].[OH-],test
US20080027077A1,CCCCCNC(=O)N(C)c1cccc(-c2cnc(C=CC(=O)[O-])nc2)c1>>CCCCCNC(=O)N(C)c1cccc(-c2cnc(C=CC(=O)O)nc2)c1,O,C1CCOC1,,[Na+].[OH-],,test
US20040122237A1,CCOC(C)=O.CN1CCN(c2ccc([N+](=O)[O-])c(N)c2F)CC1>>Nc1ccc(N2CCN(C3CCCC3)CC2)cc1N,O=[Mn]=O,CCOC(C)=O,,,,test
US20090239854A1,CC(C)(C)Oc1ccc(CCBr)cc1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>Cc1ccc2c(c1)c1c(n2CCc2ccc(OC(C)(C)C)cc2)CCN(C)C1,,CN1CCCC1=O,O,[K+].[OH-],,test
US20090311288A1,CC1(C)CO1.COc1ccc(CN(Cc2ccc(OC)cc2)c2nc3ccccc3n3cc(CC(C)C)nc23)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc3ccccc3n3c(CC(C)(C)O)c(CC(C)C)nc23)cc1,,C1CCOC1,,[Li]CCCC,,test
US20050209165A1,CC(=O)OC[C@H]1O[C@@H](c2cccc(Br)c2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.CC1(C)OB(c2ccc([C@@H]3[C@@H](CC[C@H](O[Si](C)(C)C(C)(C)C)c4ccc(F)cc4)C(=O)N3c3ccccc3)c(O[Si](C)(C)C(C)(C)C)c2)OC1(C)C>>CC(=O)OC[C@H]1O[C@@H](c2cccc(-c3ccc([C@@H]4[C@@H](CC[C@H](O[Si](C)(C)C(C)(C)C)c5ccc(F)cc5)C(=O)N4c4ccccc4)c(O[Si](C)(C)C(C)(C)C)c3)c2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],,test
US20150094330A1,COC(=O)c1ccc(CCc2cccc3c2NCC3)cc1.COc1cccc(S(=O)(=O)Cl)c1>>COC(=O)c1ccc(CCc2cccc3c2N(S(=O)(=O)c2cccc(OC)c2)CC3)cc1,,C1CCOC1,,Cl,c1ccncc1,test
US20100076027A1,COC(=O)c1ccc(/C=C/C(c2c3c(nn2-c2ccc(Cl)cc2)CCCC3)C2CCCCC2)cc1>>O=C(O)c1ccc(/C=C/C(c2c3c(nn2-c2ccc(Cl)cc2)CCCC3)C2CCCCC2)cc1,,CO,,[Na+].[OH-],,test
US20160264522A1,CC(C)(C)OC(=O)N1CC[C@H](C(=O)Nc2cc(F)c(F)c(F)c2)C1.Cl>>Cl.O=C(Nc1cc(F)c(F)c(F)c1)[C@H]1CCNC1,,ClCCl,,,,test
US20020052400A1,CC(=O)OC(C)=O.COc1ccc2c(c1)C=C(CN)C(c1ccccc1)O2>>COc1ccc2c(c1)C=C(CNC(C)=O)C(c1ccccc1)O2,,ClCCl,c1ccncc1,Cl,,test
US20160083387A1,C=C1CC[C@H]2[C@H](O)[C@@H]([C@@]3(C)CC[C@H](O[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)C[C@@H]3CCn3ccnc3)CC[C@]12C>>C=C1CC[C@H]2[C@H](O)[C@@H]([C@@]3(C)CC[C@H](O)C[C@@H]3CCn3ccnc3)CC[C@]12C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140213586A1,COc1cc(NC(C(=O)c2c[nH]c3ccccc23)c2ccc(C)cc2)cc(OCCOC(C)(C)C)c1>>COc1cc(NC(C(=O)c2c[nH]c3ccccc23)c2ccc(C)cc2)cc(OCCO)c1,,Cl,,C1COCCO1,O=C([O-])O.[Na+],test
US06486155B1,CC(C)(C)OC(=O)C(Br)C(=O)OC(C)(C)C.COc1cc(C(=O)c2cc(OC)c(OC)c(OC)c2)c(C(=O)O)cc1OCc1ccccc1>>COc1cc2c(-c3cc(OC)c(OC)c(OC)c3)c(C(=O)O)oc(=O)c2cc1OCc1ccccc1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20040259923A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCc1ccc(-c2csc(N)n2)cc1>>CC(C)(C)OC(=O)NCCc1ccc(-c2csc(N)n2)cc1,,C1COCCO1,,O,[Na+].[OH-],test
US20130079313A1,CC(C)(C)OC(=O)Oc1ccc(N(CC2CC2)S(C)(=O)=O)cc1C(=O)OCC(=O)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1>>CS(=O)(=O)N(CC1CC1)c1ccc(O)c(C(=O)OCC(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)c1,,Cl,ClCCl,C1COCCO1,,test
US20140296271A1,COCCOCCOCCNC(=O)c1cc(N)cc(C#C[Si](C(C)C)(C(C)C)C(C)C)c1>>C#Cc1cc(N)cc(C(=O)NCCOCCOCCOC)c1,,CC#N,ClCCl,[Cs+].[F-],,test
US20050143381A1,O=c1c(-c2ccncc2)c(-c2ccc(Cl)cc2)cnn1Cc1ccccc1>>O=c1[nH]ncc(-c2ccc(Cl)cc2)c1-c1ccncc1,,Cc1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120202853A1,C/C=C(/C)B(O)O.Cc1nn(-c2ccc(O)cc2F)c(I)c1C#N>>C/C=C(/C)c1c(C#N)c(C)nn1-c1ccc(O)cc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20150038528A1,C1CCC2=NCCCN2CC1.CC(=O)N(C)C.COC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O.NCC(C(=O)O)c1ccccc1F>>N#Cc1nc(C(=O)NCC(C(=O)O)c2ccccc2F)c(O)c2ccc(Oc3ccccc3)cc12,,CC(=O)N(C)C,,Cl,,test
US20120289501A1,CC(C)[Si](Oc1ccc(Br)c(O)c1)(C(C)C)C(C)C.O[C@@H](CCCl)c1ccccc1>>CC(C)[Si](Oc1ccc(Br)c(O[C@H](CCCl)c2ccccc2)c1)(C(C)C)C(C)C,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110230486A1,Cc1cc(Oc2ccc(F)cc2)cc(C)c1C(=O)CBr.NC(N)=S>>Cc1cc(Oc2ccc(F)cc2)cc(C)c1-c1csc(N)n1,,CCO,,,,test
US20130035354A1,N#Cc1ccc(-c2cncc(N)c2)cc1Cl.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>N#Cc1ccc(-c2cncc(NS(=O)(=O)c3ccc(C(F)(F)F)cc3)c2)cc1Cl,,c1ccncc1,,,,test
US20130184284A1,C[C@]1(NC(=O)OCc2ccccc2)CCCN(c2ccc(C(F)(F)F)cc2)C1>>C[C@]1(N)CCCN(c2ccc(C(F)(F)F)cc2)C1,[Pd],CO,,,,test
US20090275570A1,O=C(O)Cc1cccs1.O=C(OCc1ccccc1)N1CCCC(O)C1>>CC(=O)SC1CCCN(C(=O)OCc2ccccc2)C1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120035201A1,CON1CCC2(CC1)NC(=O)C(c1cc(C)ccc1C)C2=O.O=S(=O)(Cl)Cl>>CON1CCC2(CC1)NC(=O)C(Cl)(c1cc(C)ccc1C)C2=O,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20040220193A1,CCOC(=O)C1CN(CCCC(C#N)(c2ccccc2)C(C)C)CCN1Cc1ccccc1>>CCOC(=O)C1CN(CCCC(C#N)(c2ccccc2)C(C)C)CCN1,[Pd],CCO,,[H][H],,test
US04198527,C=C(C)CCl.Oc1ccc(Cl)cc1>>C=C(C)COc1ccc(Cl)cc1,,C1CCOC1,CCOCC,[H-].[Na+],,test
US20080214448A1,COC(=O)CCCCCCc1nc(-c2ccccc2)co1>>O=C(O)CCCCCCc1nc(-c2ccccc2)co1,,CO,O,Cl,[Na+].[OH-],test
US20120123126A1,COc1cc2c(Oc3ccc(N(C(=O)C4(C(N)=O)CC4)c4ccc(F)cc4)cc3F)ccnc2cc1OCC1(N)CC1.O=C1CCOCC1>>COc1cc2c(Oc3ccc(N(C(=O)C4(C(N)=O)CC4)c4ccc(F)cc4)cc3F)ccnc2cc1OCC1(NC2CCOCC2)CC1,,ClCCl,,CC(=O)O,O=C([O-])O.[Na+],test
US20120142717A1,COC(=O)CC(C=O)C(=O)OC.N=C(N)OCCc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cc1>>COC(=O)Cc1c[nH]c(OCCc2ccc(Oc3ccc(Cl)c(C(F)(F)F)c3)cc2)nc1=O,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US05175162,CC(=O)O.O=C(CCl)c1cc2c(s1)SCCc1cc(=O)n(-c3ccc(Cl)cc3)nc1-2>>CC(=O)OCC(=O)c1cc2c(s1)SCCc1cc(=O)n(-c3ccc(Cl)cc3)nc1-2,,CC(=O)O,,O,CC(=O)[O-].[K+],test
US20110230403A1,CCOc1ccc(Cc2cc([C@@H]3O[C@H](CI)[C@@H](O)[C@H](O)[C@H]3O)ccc2Cl)cc1.Nc1ccc(F)c(S)c1>>CCOc1ccc(Cc2cc([C@@H]3O[C@H](CSc4cc(N)ccc4F)[C@@H](O)[C@H](O)[C@H]3O)ccc2Cl)cc1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020091261A1,CC(=O)Nc1ccc(N)cc1.Clc1nnc(Cc2ccncc2)c2ccccc12>>CC(=O)Nc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1,,CCCCO,,,,test
US20040186140A1,CC(C)N(C)[C@@H]1CC[C@H](N2CC[C@H](NC(=O)c3cccc(Cl)c3)C2=O)[C@H](CS(=O)(=O)c2ccc(Cl)cc2)C1.O=C(OO)c1cccc(Cl)c1>>CC(C)N(C)[C@@H]1CC[C@H](N2CC[C@H]([NH+]([O-])C(=O)c3cccc(Cl)c3)C2=O)[C@H](CS(=O)(=O)c2ccc(Cl)cc2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040132727A1,CC(=O)OCBr.Oc1ccc(Cl)cc1Cl>>O=C(O)COc1ccc(Cl)cc1Cl,,CN(C)C=O,,O,[H-].[Na+],test
US20060074102A1,CC(C)N.ClC(Cl)(Cl)c1nc(-c2cc3c(Nc4ccc(-c5ccccc5)cc4)cncc3s2)no1>>CC(C)Nc1nc(-c2cc3c(Nc4ccc(-c5ccccc5)cc4)cncc3s2)no1,,CCO,,,,test
US04871841,NN1CCCNC1=O.O=C(Cl)OCc1ccccc1>>O=C(NN1CCCNC1=O)OCc1ccccc1,,C1CCOC1,O,Cl,,test
US20150329538A1,CON(C)C(C)=O.Clc1ccc2cccc(Br)c2n1>>CC(=O)c1cccc2ccc(Cl)nc12,,C1CCOC1,,[Li]CCCC,,test
US20150099880A1,CC(C)NC[C@@H](C(=O)N1CCN(c2ncnc3c2[C@H](C)C[C@H]3O)CC1)c1ccc(Cl)cc1.Cc1ccc(S(=O)(=O)O)cc1>>CC(C)NC[C@@H](C(=O)N1CCN(c2ncnc3c2[C@H](C)C[C@H]3O)CC1)c1ccc(Cl)cc1.Cc1ccc(S(=O)(=O)O)cc1,,CC#N,,O,,test
US05545669,O=C(O)c1ccccc1Oc1ccc(Br)cc1[N+](=O)[O-]>>Nc1cc(Br)ccc1Oc1ccccc1C(=O)O,,CC(=O)O,,CCO,O,test
US04050921,Cc1ccc(C)c(C(=O)CSc2cccc[n+]2[O-])c1.O=C(OO)c1cccc(Cl)c1>>Cc1ccc(C)c(C(=O)CS(=O)c2cccc[n+]2[O-])c1,,ClC(Cl)Cl,,,,test
US20040259804A1,CC(C)[C@H](NC(=O)COc1cccc2ccccc12)C(=O)NC(CC(=O)OC(C)(C)C)C(=O)CF>>CC(C)[C@H](NC(=O)COc1cccc2ccccc12)C(=O)NC(CC(=O)O)C(=O)CF,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US05843904,CCOC(=O)CN(Cc1ccccc1)C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C.O=C(Cl)c1ccccc1>>CCOC(=O)CN(Cc1ccccc1)C(=O)[C@@H](NC(=O)c1ccccc1)C(C)C,,CCOC(C)=O,Cl,CCN(C(C)C)C(C)C,,test
US20090093478A1,CC(C)(C)OC(=O)N1CCC[C@H]1CN.Clc1cnc(Cl)nc1>>CC(C)(C)OC(=O)N1CCCC1CNc1ncc(Cl)cn1,,Cc1ccccc1C,,CCN(C(C)C)C(C)C,O=C([O-])[O-].[K+].[K+],test
US20040157891A1,COc1ccc(-c2nc(C(F)(F)F)oc2-c2ccc(OCCN)cc2)cc1.Cl>>COc1ccc(-c2nc(C(F)(F)F)oc2-c2ccc(OCCN)cc2)cc1.Cl,,CO,,,,test
US20080027036A1,CCOC(CBr)OCC.Oc1ccc(Sc2ccccc2)cc1>>CCOC(COc1ccc(Sc2ccccc2)cc1)OCC,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20110071150A1,CCn1nc(-c2ccccc2)cc1-c1ccc2c(c1)cc(-c1c(F)cccc1F)n2S(=O)(=O)c1ccccc1>>CCn1nc(-c2ccccc2)cc1-c1ccc2[nH]c(-c3c(F)cccc3F)cc2c1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20060258740A1,CC(C)N(NC(=O)c1ccccc1)C(=O)CCc1ccccc1Br.Cc1ccc(C)c(B(O)O)c1>>Cc1ccc(C)c(-c2ccccc2CCC(=O)N(NC(=O)c2ccccc2)C(C)C)c1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US06180627B2,COCC(NC(=O)OC(C)(C)C)c1cccc(CCN)c1.Cc1c(Cl)nc(Cl)c(=O)n1CC(=O)OCc1ccccc1>>COCC(NC(=O)OC(C)(C)C)c1cccc(CCNc2nc(Cl)c(C)n(CC(=O)OCc3ccccc3)c2=O)c1,,CCOC(C)=O,,CCN(CC)CC,,test
US20020022628A1,O=CO.O=S(=O)(CC(CCc1cncc(Cl)c1)NO)N1CCN(c2ccc(Cl)cc2)CC1>>O=CN(O)C(CCc1cncc(Cl)c1)CS(=O)(=O)N1CCN(c2ccc(Cl)cc2)CC1,,C1CCOC1,,CC(=O)OC(C)=O,,test
US20150225390A1,O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCC(N(C(=O)c2ccc(-c3cnco3)cc2)C2CC2)CC1.OC1CCOCC1>>O=C(OC1CCOCC1)N1CCC(N(C(=O)c2ccc(-c3cnco3)cc2)C2CC2)CC1,,C1CCOC1,CCOC(C)=O,[H-].[Na+],O=C([O-])[O-].[K+].[K+],test
US20140088079A1,BrP(Br)Br.OCc1cc([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)ccc1Cl>>Clc1ccc([C@@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1CBr,,CCOCC,,c1ccncc1,,test
US20150119390A1,CCN(CC)S(F)(F)F.COc1cc(OCc2cccc(C3(O)CCOCC3)n2)c2cc(-c3cn4nc([C@H](C)F)sc4n3)oc2c1>>COc1cc(OCc2cccc(C3(F)CCOCC3)n2)c2cc(-c3cn4nc([C@H](C)F)sc4n3)oc2c1,,ClCCl,,CCCCCC,CCOC(C)=O,test
US20020032207A1,O=C1CCC(Cc2ccccc2)CC1.[NH4+]>>NC1CCC(Cc2ccccc2)CC1,,CO,,[BH3-]C#N.[Na+],,test
US20020037907A1,CC(C)N(Cc1c(F)cccc1F)C(=O)Nc1ccc(S(=O)(=O)N2CCC(C=O)CC2)cc1.CS(=O)(=O)Nc1cc([C@@H](O)CN)ccc1O>>CC(C)N(Cc1c(F)cccc1F)C(=O)Nc1ccc(S(=O)(=O)N2CCC(CNC[C@H](O)c3ccc(O)c(NS(C)(=O)=O)c3)CC2)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US04500346,CC(Br)C(=O)OCCSCc1ccccc1.Oc1ccc(O)cc1>>CC(Oc1ccc(O)cc1)C(=O)OCCSCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160130268A1,CC(C)(C)OC(=O)Nc1ccc(CCOS(C)(=O)=O)nc1.COc1cc(OC)c(Cl)c(-c2cc3cnc(SC)nc3[nH]c2=O)c1>>COc1cc(OC)c(Cl)c(-c2cc3cnc(SC)nc3n(CCc3ccc(NC(=O)OC(C)(C)C)cn3)c2=O)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040254183A1,CC(C)Cn1c(NN=Cc2c[nH]c3ccc(Cl)cc23)cc(=O)n(C)c1=O.Cn1cc(C#N)cc1C=O>>CC(C)Cn1c(=O)n(C)c(=O)c2c(-c3cc(C#N)cn3C)n(Cc3c[nH]c4ccc(Cl)cc34)nc21,,CN(C)C=O,,C1CCNCC1,,test
US20090247729A1,C1=C2CCC(=C1)C2.Cl[Pd]Cl>>C1=C2CCC(=C1)C2.Cl[Pd]Cl,,CO,,[Cl-].[Li+],,test
US06380230B1,CCOC(=O)CCCCCBr.O=C(OCc1ccccc1)c1cc2ccccc2[nH]1>>CCOC(=O)CCCCCn1c(C(=O)OCc2ccccc2)cc2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20090198063A1,CC(=O)Cl.O=c1cc(CO)[nH]cc1OCc1ccccc1>>CC(=O)OCc1cc(=O)c(OCc2ccccc2)c[nH]1,,c1ccncc1,,,,test
US20090247517A1,CC(C)c1ccc(C(=O)Nc2ccc(Cl)cc2)cc1.CCOC(=O)c1noc(-c2ccccc2)c1N>>CC(C)c1ccc(-c2nc3c(-c4ccccc4)onc3c(=O)n2-c2ccc(Cl)cc2)cc1,,O=S(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US20100286116A1,Cc1nc(CCc2c(-c3ccccc3)noc2C)sc1C(=O)O.N[C@H]1CCOC1>>Cc1nc(CCc2c(-c3ccccc3)noc2C)sc1C(=O)N[C@H]1CCOC1,,Cc1ccccc1,,C[Al](C)C,Cl,test
US20120309736A1,CCOC(=O)C1CCC(O)C1.C[Si](C)(C)CCOCn1c(S(C)(=O)=O)nc2cc(-c3ccc(-c4ccccc4)cc3)c(Cl)cc21>>CCOC(=O)C1CCC(Oc2nc3cc(-c4ccc(-c5ccccc5)cc4)c(Cl)cc3n2COCC[Si](C)(C)C)C1,,CCOC(C)=O,CN(C)C=O,,,test
US20060030613A1,Clc1cc(Br)c2[nH]ccc2c1.O=C=O>>O=C(O)c1cc(Cl)cc2cc[nH]c12,,C1CCOC1,CCCCCC,O,[Li]CCCC,test
US20120101127A1,CC1(C)CC(c2cccc(N)c2)Nc2ccc(Cl)cc21.O=S(=O)(Cl)c1ccccc1>>CC1(C)CC(c2cccc(NS(=O)(=O)c3ccccc3)c2)Nc2ccc(Cl)cc21,,c1ccncc1,,,,test
US20130178499A1,CC(=O)Cl.O=C1CCc2cc(O)cc(F)c2N1>>CC(=O)Oc1cc(F)c2c(c1)CCC(=O)N2,,ClCCl,,,,test
US20140213586A1,CCOc1ncc(N)cc1OC.O=Cc1ccccc1>>CCOc1ncc(N=Cc2ccccc2)cc1OC,,CCO,,,,test
US20050014942A1,CI.c1ccc(-c2cc3nccnc3[nH]2)cc1>>Cn1c(-c2ccccc2)cc2nccnc21,,CN(C)C=O,,[H-].[Na+],,test
US20140045862A1,C1CCOC1.CC1(C)CCCC1=O.c1cn[nH]c1>>Cn1nccc1C1(O)CCCC1(C)C,,C1CCOC1,,[Li]CCCC,,test
US20060024330A1,CC(=O)N1C=CN(Cc2ccc(F)cc2)C(=O)C1>>CC(=O)N1CCN(Cc2ccc(F)cc2)C(=O)C1,[Pd],CCO,,,,test
US20090239854A1,C=Cc1ccc(C(C)C)nc1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>Cc1ccc2c(c1)c1c(n2CCc2ccc(C(C)C)nc2)CCN(C)C1,,CN1CCCC1=O,O,[K+].[OH-],,test
US06265411B1,CCOC(=O)CC(=O)OCC.N#Cc1ccc(Cl)c([N+](=O)[O-])c1>>CCOC(=O)C(C(=O)OCC)c1ccc(C#N)cc1[N+](=O)[O-],,CN(C)C=O,,Cl,[H-].[Na+],test
US20010049381A1,COc1ccc(CCCBr)cc1.NC(N)=S>>COc1ccc(CCCS)cc1,,CCO,O,[Na+].[OH-],,test
US20050282887A1,NCC1COc2ccccc2O1.NS(N)(=O)=O>>NS(=O)(=O)NCC1COc2ccccc2O1,,C1COCCO1,,,,test
US20050009867A1,COc1cc2c(Cl)c(C#N)cnc2cc1O.Nc1cccc2c1OCO2>>COc1cc2c(Nc3cccc4c3OCO4)c(C#N)cnc2cc1O,,CCCO,,,,test
US05043447,Cc1ccc(-c2nc(CCl)c(C)[nH]2)cc1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>Cc1ccc(-c2nc(CN3CCN(C(c4ccccc4)c4ccccc4)CC3)c(C)[nH]2)cc1,,CCO,O,Cl,[Na+].[OH-],test
US20110105461A1,BrCC1CO1.O=Cc1cc(Br)ccc1O>>O=Cc1cc(Br)ccc1OCC1CO1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20030004181A1,COCc1nc(CO)cn1C.COCc1ncc(CO)n1C.O=C1CCC(=O)N1Cl>>COCc1nc(CO)c(Cl)n1C,,CCOCCO,,C1COCCO1,,test
US20060004084A1,O=C1Nc2ccc(F)cc2C1=C1OCc2cc(CCCOC(=O)C34CC5CC(C3)CC([N+](=O)[O-])(C5)C4)ccc21>>NC12CC3CC(C1)CC(C(=O)OCCCc1ccc4c(c1)COC4=C1C(=O)Nc4ccc(F)cc41)(C3)C2,[Zn],CC(=O)O,,,,test
US20090075996A1,CC1(C)CC(=O)c2ccc(O)cc21.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC1(C)CC(=O)c2ccc(OS(=O)(=O)C(F)(F)F)cc21,,ClCCl,,CCN(CC)CC,,test
US20090163488A1,Cc1cc(C(=O)Cl)n(C)n1.Nc1cc(O)ccc1F>>Cc1cc(C(=O)Nc2cc(O)ccc2F)n(C)n1,,C1CCOC1,O,CCN(CC)CC,,test
US20120010247A1,CCCCC(CC)COC(=O)CCS.COC(=O)c1ccc([N+](=O)[O-])c(F)c1>>CCCCC(CC)COC(=O)CCSc1cc(C(=O)OC)ccc1[N+](=O)[O-],,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04939126,CNCCN(CCNC(=O)CN1CCCC1=O)C(C)C.C[Si](C)(C)CCl>>CC(C)N(CCNC(=O)CN1CCCC1=O)CCN(C)C[Si](C)(C)C,,CO,,[Na+].[OH-],,test
US20120157430A1,CC(=O)c1cc(Cl)c(C)c(N(S(C)(=O)=O)S(C)(=O)=O)c1-c1cccc(F)c1.[NH4+]>>Cc1c(Cl)cc(C(C)N)c(-c2cccc(F)c2)c1N(S(C)(=O)=O)S(C)(=O)=O,,CC#N,CO,[BH3-]C#N.[Na+],,test
US20030092712A1,COc1cc(-c2ccc(F)cc2F)c2c(c1)N(c1c(Cl)cccc1Cl)C(=O)CC2.Cl.ClCCl>>COc1cc(-c2ccccc2Cl)c2ccc(=O)n(-c3c(Cl)cccc3Cl)c2c1.Cl,,C1COCCO1,ClCCl,,,test
US20070238726A1,O=c1c(-c2ccc(OCc3ccccc3)c(F)c2)cncn1Cc1ccc(Cl)cc1>>O=c1c(-c2ccc(O)c(F)c2)cncn1Cc1ccc(Cl)cc1,,O=C(O)C(F)(F)F,,,,test
US06703397B2,CC(C)S(=O)(=O)Cl.Cn1ccc2c(O)cc(Cc3cnc(N)nc3N)cc21>>CC(C)S(=O)(=O)Oc1cc(Cc2cnc(N)nc2N)cc2c1ccn2C,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20100029619A1,CC(C)(C(=O)O)c1ccc(C(=O)Nc2cn3cc(Cl)ccc3n2)cc1.CCN=C=NCCCN(C)C.N#CCN>>CC(CC#N)(C(=O)NCC#N)c1ccc(C(=O)Nc2cn3cc(Cl)ccc3n2)cc1,,CN(C)C=O,O,On1nnc2ccccc21,,test
US05281593,CN(C)C=O.COP(=O)(O)C(C)(C)C(=O)[O-].O=Cc1ccc(OCc2ccccc2)c2[nH]ccc12>>COC(=O)/C=C/c1ccc(OCc2ccccc2)c2[nH]ccc12,,C1CCOC1,,[H-].[Na+],,test
US04254119,C=[N+]=[N-].O=C(Nc1nc(C(=NO)C(=O)N[C@@H]2C(=O)N3C(C(=O)OC(c4ccccc4)c4ccccc4)=CCS[C@H]23)c(F)s1)OCc1ccccc1>>CON=C(C(=O)N[C@@H]1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=CCS[C@H]12)c1nc(NC(=O)OCc2ccccc2)sc1F,,CCOCC,ClCCl,,,test
US20040106607A1,CC(C)(C)OC(=O)N1CCCCC1c1nc(-c2cccc(C#N)c2)no1>>N#Cc1cccc(-c2noc(C3CCCCN3)n2)c1,,O=CO,,,,test
US20110071139A1,O=C(CCNc1cccc(Br)c1)c1ccccc1Cl>>OC(CCNc1cccc(Br)c1)c1ccccc1Cl,,C1CCOC1,CO,[BH4-].[Na+],,test
US20080318943A1,COc1ccc(CN2CC(Nc3c(Br)cccc3C#N)=CC2=O)cc1>>COc1ccc(CN2Cc3nc4c(Br)cccc4c(N)c3C2=O)cc1,,CCO,,C,C[O-].[Na+],test
US20100063119A1,CC(=O)OC(C)=O.CC(O)CCCOCc1ccccc1>>CC(=O)OC(C)CCCOCc1ccccc1,,c1ccncc1,,CO,,test
US20160016960A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc(C(=O)NCC(=O)Cc3ccc(F)cc3)nn2c1C1=CCC(C)(C)CC1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc(-c3ncc(Cc4ccc(F)cc4)s3)nn2c1C1=CCC(C)(C)CC1,,Cc1ccccc1,,,,test
US20100048568A1,Cc1ccc(S(=O)(=O)n2ccc3cc(F)ccc32)cc1.O=S(=O)(O)Cl>>Cc1ccc(S(=O)(=O)n2cc(S(=O)(=O)Cl)c3cc(F)ccc32)cc1,,CC#N,,,,test
US20090312241A1,C=Cc1cccc(-c2cccc(CO[C@@H]3C[C@@H](C(=O)OC)N(C(=O)[C@@H](NC(=O)OC(C)(C)C)C4CCCCC4)C3)c2)c1.Cl>>C=Cc1cccc(-c2cccc(CO[C@@H]3C[C@@H](C(=O)OC)N(C(=O)[C@@H](N)C4CCCCC4)C3)c2)c1.Cl,,C1COCCO1,,,,test
US20140256719A1,COC(=O)C(N)CS(N)(=O)=O.O=C(O)c1cncc(-c2nc(NCc3ccccc3)c3c(-c4ccccc4)ccn3n2)c1>>COC(=O)C(CS(N)(=O)=O)NC(=O)c1cncc(-c2nc(NCc3ccccc3)c3c(-c4ccccc4)ccn3n2)c1,CN(C)c1ccncc1,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20090029987A1,COc1cc(O)c(C(=O)CC(=O)c2ccncc2)c(OC)c1.Cl>>Cl.O=c1ccoc2ccccc12,,O,,CC(=O)O,O=C([O-])O.[Na+],test
US06147031,BrCc1ccccc1.Cc1c(C(=O)c2cnn(C)c2O)ccc(S(C)(=O)=O)c1C1=NOCC1>>Cc1c(C(=O)c2cnn(C)c2OCc2ccccc2)ccc(S(C)(=O)=O)c1C1=NOCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160016908A1,C/C=C/NC(=O)OCc1ccccc1.ClCCl.Nc1ccc(Br)cc1.O=CC1CC1.O=P([O-])(Oc1ccccc1)Oc1ccccc1>>C[C@@H]1[C@@H](NC(=O)OCc2ccccc2)c2cc(OC3CCOCC3)ccc2N[C@H]1C1CC1,,ClCCl,,,,test
US04794188,CC(C)(CCCCOc1ccccc1)C(=O)c1cccc(OCc2ccc3ccccc3n2)c1.C[Mg]Br>>CC(C)(CCCCOc1ccccc1)C(C)(O)c1cccc(OCc2ccc3ccccc3n2)c1,,CCOCC,,[Cl-].[NH4+],,test
US20120142705A1,COC(=O)C(CC(C)C)N1C(=O)C(=O)c2cc(Cl)ccc21>>CC(C)CC(C(=O)O)N1C(=O)C(=O)c2cc(Cl)ccc21,,C1CCOC1,O,[Li+].[OH-],,test
US20060194816A1,O=C(CCl)c1ccc(Cl)cc1Cl.O=Cc1ccc(I)cc1O>>O=C(c1cc2ccc(I)cc2o1)c1ccc(Cl)cc1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130267510A1,Cc1ccc(Oc2ccc([N+](=O)[O-])cn2)c2c1OCC2(C)C>>Cc1ccc(Oc2ccc(N)cn2)c2c1OCC2(C)C,[Pd],CCO,,,,test
US20080207897A1,C#CCCN.O=C=NCCCl>>C#CCCNC(=O)NCCCl,,CCOCC,,,,test
US20150057443A1,CC(CF)NCC(O)C1(c2ccc(Cl)c(Cl)c2)CCC1.Cl>>CC(CF)[NH2+]CC(O)C1(c2ccc(Cl)c(Cl)c2)CCC1.[Cl-],,C1COCCO1,,,,test
US20040248893A1,CNC(=O)c1c(C)noc1-c1ccccc1.N#Cc1ccccc1>>Cn1c(-c2ccccc2)cc2noc(-c3ccccc3)c2c1=O,,C1CCOC1,,[Li]CCCC,,test
US20030225097A1,CCOC(=O)CBr.O=C1NCCC1Cc1ccccc1>>CCOC(=O)CN1CCC(Cc2ccccc2)C1=O,,C1CCOC1,,[H-].[Na+],,test
US04791207,CC(C)[C@H]1COC(=O)N1.CCC(=O)Cl>>CCC(=O)N1C(=O)OC[C@@H]1C(C)C,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20060128702A1,CSc1ccc(-c2cc(Cl)c3ccccc3n2)cc1.FC(F)(F)c1cc[nH]n1>>CSc1ccc(-c2cc(-n3ccc(C(F)(F)F)n3)c3ccccc3n2)cc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US04937373,COc1c(C)cc(C)c(C)c1OC.O=C(Cl)CCCCCBr>>COc1c(C)c(C)c(C(=O)CCCCCBr)c(C)c1OC,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20050130976A1,NN.Nc1cnnc2c(F)c(Nc3ccc(Br)cc3F)c(C(=O)O)cc12>>NNC(=O)c1cc2c(N)cnnc2c(F)c1Nc1ccc(Br)cc1F,,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US04797403,CN1C=NN(c2cccc([N+](=O)[O-])c2)N1>>CN1C=NN(c2cccc(N)c2)N1,O=[Pt],CCO,,[H][H],,test
US20120172382A1,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.Nc1cc(F)c(Oc2ccnc(N)c2I)cc1F>>Cn1cc(-c2c(Oc3cc(F)c(N)cc3F)ccnc2N)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US05665719,COC(=O)c1ccc(OCC2CCN(C(=O)OC(C)(C)C)CC2)cc1OC>>COc1cc(OCC2CCN(C(=O)OC(C)(C)C)CC2)ccc1C(=O)O,,CO,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[Na+].[OH-],test
US20100093781A1,CCOC(=O)c1cc2c3n(ccc-2n1)CC(C)=N3>>CC1=Nc2c3cc(C(=O)O)nc-3ccn2C1,,C1CCOC1,CCO,Cl,[K+].[OH-],test
US04407743,CCOC(=O)CN.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)CNS(=O)(=O)C(F)(F)F,,ClCCl,,CCN(CC)CC,Cl,test
US04962115,CCOC(=O)c1cc(C#N)c(N)cc1OC>>COc1cc(N)c(C#N)cc1C(=O)O,,O,,[Na+].[OH-],,test
US20150133424A1,CCOC(=O)C(C)(C)Br.O=[N+]([O-])c1cccc(O)c1>>CCOC(=O)C(C)(C)Oc1cccc([N+](=O)[O-])c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090137607A1,C=Cc1cnc2nc(-c3ccc(C=O)cc3)c(-c3ccccc3)cn12>>CCc1cnc2nc(-c3ccc(C=O)cc3)c(-c3ccccc3)cn12,[Pd],C1CCOC1,CCO,,,test
US20060264460A1,COc1ccc(C=O)cc1OCCN1CCOCC1.N#Cc1cnc2c(Cl)cc(N)cc2c1Nc1ccc(F)c(Cl)c1>>COc1ccc(CNc2cc(Cl)c3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)cc1OCCN1CCOCC1,,CCO,,[BH3-]C#N.[Na+],,test
US20070149544A1,CC(C)(C)OC(=O)N1CCN(c2ccc(Cc3ccccc3)cc2)CC1.Cl>>Cl.c1ccc(Cc2ccc(N3CCNCC3)cc2)cc1,,C1COCCO1,,,,test
US20070232591A1,CC(C)(C)OC(=O)CN1CCc2nc(C(=O)NC3CCC3)ccc2C1.Cl>>Cl.O=C(O)CN1CCc2nc(C(=O)NC3CCC3)ccc2C1,,C1COCCO1,,,,test
US20110015157A1,CC#N.CC(=O)c1cccc(Cl)c1>>CC(O)(CC#N)c1cccc(Cl)c1,,C1CCOC1,,[Li]CCCC,,test
US20100298323A1,CCOC(=O)C1CCC(OCC)(OCC)CC1>>CCOC1(OCC)CCC(CO)CC1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050059726A1,CC(C)(C)OC(=O)N[C@H]1CCN(c2ccc(N)cc2F)C1=O.CC(C)C(=O)Cl>>CC(C)C(=O)Nc1ccc(N2CC[C@H](NC(=O)OC(C)(C)C)C2=O)c(F)c1,,ClCCl,,,,test
US20130012526A1,NCCSc1ccc(Cl)cc1.O=C(O)C1CCOCC1>>O=C(NCCSc1ccc(Cl)cc1)C1CCOCC1,,CCOC(C)=O,CN(C)C=O,ClCCCl,On1nnc2cccnc21,test
US20150225397A1,Cc1nc(Cl)c2c(n1)[C@@]1(c3ccccc3)CCC(=O)[C@@H](C)[C@@H]1CC2.Cn1cncc1B1OC(C)(C)C(C)(C)O1>>Cc1nc(-c2cncn2C)c2c(n1)[C@@]1(c3ccccc3)CCC(=O)[C@@H](C)[C@@H]1CC2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20140296208A1,COc1cc(Nc2nccc(Oc3ccc(NC(=O)OC(C)(C)C)c4ccccc34)n2)cc(S(=O)(=O)C2CC2)c1>>COc1cc(Nc2nccc(Oc3ccc(N)c4ccccc34)n2)cc(S(=O)(=O)C2CC2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06433174B1,C[C@H](N)c1ccccc1.O=C(O)CC(C(=O)OCc1ccccc1)c1ccc(Cl)c(Cl)c1>>C[C@H](N)c1ccccc1.O=C(O)CC(C(=O)OCc1ccccc1)c1ccc(Cl)c(Cl)c1,,CC(C)O,,C1CCC2=NCCCN2CC1,,test
US06660744B1,Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CCNC1.O=Cc1ncc[nH]1>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CCN(Cc2ncc[nH]2)C1,,ClCCCl,,CC(=O)O,O=C([O-])O.[Na+],test
US20040210080A1,C=CC(C)=O.CCCCC1Cc2c(cc(F)c(N)c2Cl)C1=O>>CCCCC1(CCC(C)=O)Cc2c(cc(F)c(N)c2Cl)C1=O,,CO,,C[O-].[Na+],,test
US20030225053A1,COC(=O)c1cc2cccc([N+](=O)[O-])c2s1>>O=C(O)c1cc2cccc([N+](=O)[O-])c2s1,,C1CCOC1,CO,[Na+].[OH-],,test
US20040077675A1,COC(=O)c1c(-c2c(F)cccc2F)noc1C>>Cc1onc(-c2c(F)cccc2F)c1C(=O)O,,CO,,[Na+].[OH-],,test
US20100015178A1,O=C(Nc1nonc1-c1noc(=O)n1-c1ccc(F)c(Cl)c1)C(F)(F)F.O=C(O)C(F)(F)F.OCCCN=C(c1ccccc1)c1ccccc1>>NCCCNc1nonc1-c1noc(=O)n1-c1ccc(F)c(Cl)c1.O=C(O)C(F)(F)F,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04786646,CC(N)CCCc1cccnc1.O=C(O)[C@H](O)c1ccccc1>>CC(CCCc1cccnc1)NC(=O)C(O)c1ccccc1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20070191604A1,CC(O)C1(C(=O)Nc2ccc3c(c2)c(-c2ccc(F)cc2)nn3C(c2ccccc2)(c2ccccc2)c2ccccc2)CCNC1.CC1CN(c2ccc(-c3ncccn3)cn2)CCN1C(=O)CCl>>CC1CN(c2ccc(-c3ncccn3)cn2)CCN1C(=O)CN1CCC(C(=O)Nc2ccc3c(c2)c(-c2ccc(F)cc2)nn3C(c2ccccc2)(c2ccccc2)c2ccccc2)(C(C)O)C1,,CN(C)C=O,,,,test
US20160122335A1,CC(C)(O)C(=O)O.COC(=O)C(C)(C)CC(=O)ON=C(N)c1nc(COCOCC[Si](C)(C)C)cs1>>CC(C)(O)c1nc(-c2nc(COCOCC[Si](C)(C)C)cs2)no1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110118261A1,CC1CN(c2ccc(-n3ccc(OCc4ccc(Cl)cn4)cc3=O)cn2)CC1N(C)C(=O)OC(C)(C)C>>CNC1CN(c2ccc(-n3ccc(OCc4ccc(Cl)cn4)cc3=O)cn2)CC1C,,ClCCl,O=C(O)C(F)(F)F,,,test
US20120277192A1,CC(C)(C)OC(=O)NCc1ccc2c(c1)C(=O)NC2>>NCc1ccc2c(c1)C(=O)NC2,,Cl,,,,test
US20140024650A1,CC(O)CN.COc1ccc(C(=O)Cl)cc1>>COc1ccc(C(=O)NCC(C)O)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20040192735A1,CN.COC(=O)c1ccccc1Nc1ccc2c(C(=O)O)nn(C3CCCCO3)c2c1>>CNC(=O)c1nn(C2CCCCO2)c2cc(Nc3ccccc3C(=O)OC)ccc12,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05677311,CC#C[C@H](C)Oc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(C(=O)OCC)C[C@H]1OC>>CC#C[C@H](C)Oc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCNC[C@H]1OC,,CC(C)O,,O,[K+].[OH-],test
US20070225280A1,CCOC(=O)c1cnn(CCOC)c1C(F)(F)F>>COCCn1ncc(C(=O)O)c1C(F)(F)F,,CO,O,[Li+].[OH-],,test
US04377582,Fc1ccccc1.OC1CCN(c2nc(-c3ccccc3)nc3ccccc23)CC1>>c1ccc(OC2CCN(c3nc(-c4ccccc4)nc4ccccc34)CC2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20160115168A1,NCCN1CCN(C/C=C/C(=O)N2CCC[C@@H](n3nc(C(=O)NC(=O)Nc4nc5ccccc5o4)c4c(N)ncnc43)C2)CC1.O=C1N[C@H]2CS[C@@H](CCCCC(=O)ON3C(=O)CCC3=O)[C@H]2N1>>Nc1ncnc2c1c(C(=O)Nc1nc3ccccc3o1)nn2[C@@H]1CCCN(C(=O)/C=C/CN2CCN(CCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@@H]43)CC2)C1,,CN(C)C=O,,CCN(CC)CC,CS(C)=O,test
US20160168096A1,CCOC(=O)CCCOc1ccc(Br)nc1.OB(O)c1cccc(O)c1>>CCOC(=O)CCCOc1ccc(-c2cccc(O)c2)nc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,N#N,O=C([O-])[O-].[Na+].[Na+],test
US20040006099A1,CCOC(=O)C=Cc1cnccc1N1CCC(COc2ccc3c(c2)CN(C(=O)OC(C)(C)C)CC3)CC1>>CCOC(=O)C=Cc1cnccc1N1CCC(COc2ccc3c(c2)CNCC3)CC1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20140018325A1,CCCCCN([C@@H](CCC(F)(F)C=O)CO[Si](C)(C)C(C)(C)C)S(=O)(=O)c1ccc(CO[Si](C)(C)C(C)(C)C)cc1>>CCCCCN([C@@H](CCC(F)(F)CO)CO[Si](C)(C)C(C)(C)C)S(=O)(=O)c1ccc(CO[Si](C)(C)C(C)(C)C)cc1,,CCO,ClCCl,[BH4-].[Na+],[Cl-].[NH4+],test
US20130085157A1,BrBr.c1ccc(-c2csc3nnc(SCc4ccc5c(c4)OCO5)n23)cc1>>Brc1sc2nnc(SCc3ccc4c(c3)OCO4)n2c1-c1ccccc1,,ClCCl,,O=C([O-])O.[Na+],,test
US04900825,Cn1cnc([N+](=O)[O-])c1[N+](=O)[O-].Oc1ccccc1>>Cn1cnc([N+](=O)[O-])c1Oc1ccccc1,,O,,[Na+].[OH-],,test
US20110053959A1,C[C@@H]1CCc2ncnc(N3CC4(CCN(Cc5ccccc5)CC4)c4c(CNC(=O)OC(C)(C)C)cccc43)c21>>C[C@@H]1CCc2ncnc(N3CC4(CCNCC4)c4c(CNC(=O)OC(C)(C)C)cccc43)c21,[Pd],CO,,O=C[O-].[NH4+],,test
US04012513,CCOC(=O)CC1CNc2ccccc21.Clc1ncnc2ccccc12>>CCOC(=O)CC1CN(c2ncnc3ccccc23)c2ccccc21,,COCCOC,,,,test
US20060079696A1,N#Cc1ccccc1F.Sc1ccccc1>>N#Cc1ccccc1Sc1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20050250768A1,CCOC(=O)C1CCCCN1C(=O)/C=C/c1ccc(Sc2ccc3c(c2)OCCO3)c(Cl)c1>>O=C(O)C1CCCCN1C(=O)/C=C/c1ccc(Sc2ccc3c(c2)OCCO3)c(Cl)c1,,O,,CCO,[Na+].[OH-],test
US06544976B1,O=C(OCc1ccccc1)N1CC[C@H]1c1nnnn1CCCc1cccnc1>>c1cncc(CCCn2nnnc2[C@@H]2CCN2)c1,[Pd],CCO,,,,test
US20140171405A1,Clc1cc2c(cn1)c(I)nn2C1CCCCO1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cn1cc(-c2nn(C3CCCCO3)c3cc(Cl)ncc23)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20010001101A1,CCOC(=O)c1cnc2c(N)cccc2c1Cl.CCOC=C(C(C)=O)C(=O)OCC>>CCOC(=O)c1cnc2c3c(ccc2c1Cl)C(=O)C(C(C)=O)C=N3,,ClC(Cl)(Cl)Cl,,c1ccc(Oc2ccccc2)cc1,,test
US20040132727A1,COc1cc2nccc(Oc3cc(C)c(NC(=O)CCOc4ccccc4C)cc3C)c2cc1OC>>COc1cc2nccc(Oc3cc(C)c(NCCCOc4ccccc4C)cc3C)c2cc1OC,,C1CCOC1,,Cl,[Na+].[OH-],test
US04283509,CC(C)(CN)CO.O=C1OC(=O)C2=C1CCc1ccccc12>>CC(C)(CO)CN=C(O)C1=C(C(=O)O)CCc2ccccc21,,Cc1ccccc1,,O,,test
US20150376130A1,CC(C)CCN.COC(=O)c1cc(F)cnc1Cl>>CC(C)CCNc1ncc(F)cc1C(=O)O,,CCO,,[Na+].[OH-],,test
US20060148858A1,COC(=O)Cc1ccccc1O.OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1-c1ccccc1>>O=C(O)Cc1ccccc1OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1-c1ccccc1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US04833169,COc1ccc2c(c1)C(=CCC(=O)O)C2.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COc1ccc2c(c1)C(=CCN)C2,,Cc1ccccc1,,CCN(CC)CC,,test
US05998624,CCCC[Sn](CCCC)(CCCC)c1ccccc1-c1nc(C(=O)NC)cc2ccccc12.FCCCBr>>CCCC[Sn](CCCC)(CCCC)c1ccccc1-c1nc(C(=O)N(C)CCCF)cc2ccccc12,,CN(C)C=O,,[H-].[Na+],,test
US05262412,CCCCC(=O)CC(=NOC)C(=O)OCC.Fc1cc(Br)ccc1CBr>>CCCCC(=O)C(Cc1ccc(Br)cc1F)C(=NOC)C(=O)OCC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100190769A1,C1CNC1.CC(C)(C)OC(=O)N1CCC(=O)CC1>>CC(C)(C)OC(=O)N1CCC(N2CCC2)CC1,,CC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05744488,COC(=O)CCn1cc(Cc2cccnc2)c2cc(CCNC(=O)OC(C)(C)C)ccc21>>COC(=O)CCn1cc(Cc2cccnc2)c2cc(CCN)ccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090054427A1,C1CCOC1.COC(=O)c1cc(F)c(N)c(Br)c1>>C=Cc1cc(C(=O)OC)cc(F)c1N,,O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100063120A1,CCCCN=C=O.CN1C(=O)N(c2ccc(Cl)c(Cl)c2)C(=O)C1c1ccc(O)cc1>>CCCCNC(=O)Oc1ccc(C2C(=O)N(c3ccc(Cl)c(Cl)c3)C(=O)N2C)cc1,,C1CCOC1,,CCN(CC)CC,,test
US04788206,COc1ccc(/C(=C/C=C/C(=O)O)c2cccs2)cc1.O=[N+]([O-])c1ccc(O)cc1>>COc1ccc(/C(=C/C=C/C(=O)Oc2ccc([N+](=O)[O-])cc2)c2cccs2)cc1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05409943,CCOC(=N)Cc1ccccc1.Cl.Nc1ncccc1OCc1ccc(Cl)cc1Cl>>Cl.N=C(Cc1ccccc1)Nc1ncccc1OCc1ccc(Cl)cc1Cl,,CCO,,,,test
US20090012097A1,COC(=O)C(C)(C)Oc1ccc2c(c1)CCNC2.Nc1nc(-c2ccc(C(F)(F)F)cc2)cs1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COC(=O)C(C)(C)Oc1ccc2c(c1)CCN(C(=O)Nc1nc(-c3ccc(C(F)(F)F)cc3)cs1)C2,,C1CCOC1,O,CCN(CC)CC,,test
US20040192767A1,COC(=O)c1cc(CO)c(C)o1.Oc1cccc(I)c1>>COC(=O)c1cc(COc2cccc(I)c2)c(C)o1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110281884A1,CC(=O)c1cc(Cl)c2cncn2c1-c1cccc(F)c1.[NH4+]>>CC(N)c1cc(Cl)c2cncn2c1-c1cccc(F)c1,,CO,,[BH3-]C#N.[Na+],,test
US20120010183A1,Clc1cccnc1Cl.OC1CCOCC1>>Clc1cccnc1OC1CCOCC1,,C1CCOC1,,[H-].[Na+],,test
US06017918,CC(C)(C)OC(=O)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)C(Br)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20140080798A1,COC(=O)NC1(c2ccc([N+](=O)[O-])cc2)CCC1>>COC(=O)NC1(c2ccc(N)cc2)CCC1,[Pd],CO,,,,test
US20090001014A1,OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO,,OCC(O)CO,,,,test
US04044049,C=CCc1cc(-c2ccc(F)cc2)cc(C(=O)O)c1O>>CC=Cc1cc(-c2ccc(F)cc2)cc(C(=O)O)c1O,,O,,[K+].[OH-],,test
US20150291595A1,CC1(C)OB(c2cc(N)cc(F)c2)OC1(C)C.Cc1ccn2nc([C@H](C)Nc3ncnc4c3c(Br)cn4COCC[Si](C)(C)C)n(-c3ccccc3)c(=O)c12>>Cc1ccn2nc([C@H](C)Nc3ncnc4c3c(-c3cc(N)cc(F)c3)cn4COCC[Si](C)(C)C)n(-c3ccccc3)c(=O)c12,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20160237067A1,Cc1ccc(S(=O)(=O)N(C)C)cc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nnc(Cl)[nH]3)cc2)cc1.Cl>>Cc1ccc(S(=O)(=O)N(C)C)cc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3nnc(Cl)[nH]3)cc2)cc1.Cl,,C1COCCO1,,CC#N,,test
US20050119295A1,CC(C)(C)OC(=O)N1CCc2[nH]nc(-c3ccc(Cl)cc3)c2CC1.ClC1CCC1>>CC(C)(C)OC(=O)N1CCc2nn(C3CCC3)c(-c3ccc(Cl)cc3)c2CC1,,CN(C)C=O,,[H-].[Na+],,test
US20070072851A1,CNC.COC(C)(C)CCn1nc(Nc2c(Cl)cccc2Cl)c2cnc(Cl)nc21.O=C(O)C(F)(F)F>>CNc1ncc2c(Nc3c(Cl)cccc3Cl)nn(CCC(C)(C)OC)c2n1.O=C(O)C(F)(F)F,,C1COCCO1,,C1CCOC1,,test
US20160002188A1,CNN.COC(=O)c1ccc(Br)cc1F>>Cn1nc(O)c2ccc(Br)cc21,,CCOC(C)=O,,CC(=O)N(C)C,,test
US20090298834A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CN)CC1.O=C(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CNC(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140073792A1,O=C(CBr)c1ccccc1.O=C1Nc2cc(F)ccc2C1=O>>Cc1nc2cc(F)ccc2cc1O,,O,,Cl,[K+].[OH-],test
US20110052578A1,CCCS(=O)(=O)Cl.Nc1cc(Cl)cc(Br)c1F>>CCCS(=O)(=O)Nc1cc(Cl)cc(Br)c1F,,c1ccncc1,,,,test
US05270302,CCOC(=O)C(C)(Cc1c[nH]c2ccccc12)C(=O)OCC>>CCOC(=O)C(C)(Cc1c[nH]c2ccccc12)C(=O)O,,CCO,,[K+].[OH-],,test
US20060111403A1,Cc1cc(I)cc(C(=O)O)c1N.O=C(O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl>>Cc1cc(I)cc2c(=O)oc(-c3cc(C(F)(F)F)nn3-c3ncccc3Cl)nc12,,CC#N,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20110009622A1,CC(C)c1ccc(N)cc1.O=C(O)c1cc(S(=O)(=O)N2CCCCC2)ccc1O>>CC(C)Oc1ccc(NC(=O)c2cc(S(=O)(=O)N3CCCCC3)ccc2O)cc1,,Clc1ccccc1,,ClP(Cl)Cl,,test
US20060142265A1,CCOC(=O)CNCc1ccc(OC)cc1.Nc1ncc(Br)cc1CBr>>CCOC(=O)CN(Cc1ccc(OC)cc1)Cc1cc(Br)cnc1N,,CN(C)C=O,O,Br,CCN(CC)CC,test
US20070010563A1,CC(=O)c1ccc(Cl)cc1.SCCS>>CC1(c2ccc(Cl)cc2)SCCS1,,C1CCOC1,,II,,test
US05719141,CC(=O)C1Cc2ccccc2N(Cc2ccccc2)C1>>CC(=O)C1CNc2ccccc2C1,[Pd],C1CCOC1,,,,test
US04363920,CC(C(=O)c1cccs1)C(O)=S.NCC(=O)O>>CC(C(=O)c1cccs1)C(=S)NCC(=O)O,,CS(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20120245345A1,CC(C)(C)OC(=O)Nc1ccc(C(=O)CBr)nc1.COc1ccc2ncc(O)c(N)c2n1>>COc1ccc2ncc(OCC(=O)c3ccc(NC(=O)OC(C)(C)C)cn3)c(N)c2n1,,CN(C)C=O,CO,ClCCl,O=C([O-])[O-].[K+].[K+],test
US04849526,COC(=O)c1ccn2c1C(C(=O)OC)CC2>>O=C(O)c1ccn2c1C(C(=O)O)CC2,,O,,Cl,[Na+].[OH-],test
US20070232585A1,NCCc1ccccc1.O=C/C=C1\CCCc2c1cnn2-c1ccccc1>>CN(C/C=C1\CCCc2c1cnn2-c1ccccc1)Cc1ccccc1,,CO,,[BH3-]C#N.[Na+],,test
US20110136780A1,CC(C)[C@H](C(=O)O)N1Cc2c(F)cnc3[nH]cc(c23)C1=O.CC1(C#N)CNC1>>CC(C)[C@H](C(=O)N1CC(C)(C#N)C1)N1Cc2c(F)cnc3[nH]cc(c23)C1=O,CN(C)c1ccncc1,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20090227566A1,COC(=O)c1ccc(O)cc1OC1CCN(C(=O)OC(C)(C)C)CC1.COCCl>>COCOc1ccc(C(=O)OC)c(OC2CCN(C(=O)OC(C)(C)C)CC2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060293300A1,CC(N)C(=O)[O-].Cc1cc(Cl)sc1C(=O)O>>COC(=O)C(C)NC(=O)c1ccc(Cl)s1,,C1CCOC1,,CN1CCOCC1,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20150133495A1,Cc1onc(-c2ccccc2Cl)c1C(=O)Cl.N/C(=N\O)c1ccc(-c2csnn2)cc1>>Cc1onc(-c2ccccc2Cl)c1C(=O)O/N=C(\N)c1ccc(-c2csnn2)cc1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20110288065A1,Clc1cc(Cl)nc(Cl)c1.OCC1CC1>>Clc1cc(OCC2CC2)cc(Cl)n1,,CN(C)C=O,,O,[H-].[Na+],test
US20160039812A1,CC1(C)CC(Nc2cccc(C(F)(F)F)c2)=CC(=O)N1.O=C=NC(Cl)c1ccc(Br)cc1>>CC1(C)CC2=C(C(=O)N1)C(c1ccc(Br)cc1)NC(=O)N2c1cccc(C(F)(F)F)c1,,ClCCl,,,,test
US20140375943A1,BrCCOCc1ccccc1.O=C(O)c1ccc(-c2ccc(O)cc2)cc1>>O=C(OCCOCc1ccccc1)c1ccc(-c2ccc(O)cc2)cc1,,CN(C)C=O,,O=C([O-])O.[K+],,test
US20160229837A1,CC(C)(C)OC(=O)NC1CCN(c2ccc(C#N)cn2)CC1>>N#Cc1ccc(N2CCC(N)CC2)nc1,,ClCCl,,CCOC(C)=O,Cl,test
US20160083400A1,COc1ccc(C2CN3C(=O)c4cnc(C(C)C)n4NC3=N2)cc1>>CC(C)c1ncc2n1NC1=NC(c3ccc(O)cc3)CN1C2=O,,ClCCl,,BrB(Br)Br,,test
US20020137755A1,CC(C)NC(=O)CC1CCN(C(=O)OC(C)(C)C)CC1.N#Cc1cnc(Nc2cc(Cl)ncn2)s1>>CC(C)NC(=O)CC1CCN(c2cc(Nc3ncc(C#N)s3)ncn2)CC1,,CCCCO,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US06043358,CCCI.O=C(O)C1CSCCC1=O>>CCCC1(C(=O)O)CSCCC1=O,,CN(C)C=O,O,[H-].[Na+],,test
US20140221316A1,CC(C)(C)OC(=O)Nc1ccc(OC(C)(C)C)c(C(=O)O)c1.Oc1ccc(-c2cc(=S)ss2)cc1>>CC(C)(C)OC(=O)Nc1ccc(OC(C)(C)C)c(C(=O)Oc2ccc(-c3cc(=S)ss3)cc2)c1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05891889,N#Cc1ccc(C=O)cc1.NC1CCN(c2ccccc2)CC1>>N#Cc1ccc(CNC2CCN(c3ccccc3)CC2)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20040077669A1,C#CCOc1cc(Cl)ncn1.Oc1ccc(Cl)c(Cl)c1>>C#CCOc1cc(Oc2ccc(Cl)c(Cl)c2)ncn1,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20130005705A1,CCOC(=O)c1c(Br)ccnc1CBr.NCCc1ccc2ccccc2n1>>O=C1c2c(Br)ccnc2CN1CCc1ccc2ccccc2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05972972,BrP(Br)Br.OCc1ccc(Oc2ccc(F)cc2)cc1>>Fc1ccc(Oc2ccc(CBr)cc2)cc1,,O,c1ccccc1,c1ccncc1,,test
US20120077799A1,CC1(C)OB(c2ccc(C3=CC=CN4CCS(=O)(=O)N=C34)cc2)OC1(C)C.Fc1ccccc1I>>O=S1(=O)CCN2CCCC(c3ccc(-c4ccccc4F)cc3)C2=N1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110171159A1,Brc1ccc(C2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1Cc1ccc2c(c1)CCCO2.OB(O)C1CC1>>c1ccc(COC[C@H]2OC(c3ccc(C4CC4)c(Cc4ccc5c(c4)CCCO5)c3)[C@H](OCc3ccccc3)[C@@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)cc1,,Cc1ccccc1,O,C1CCC(P(C2CCCCC2)C2CCCCC2)CC1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20160007606A1,COC(=O)C1CNCCN1C(=O)OC(C)(C)C.Fc1cccc(F)c1C1CC(c2csc(Br)n2)=NO1>>COC(=O)C1CN(c2nc(C3=NOC(c4c(F)cccc4F)C3)cs2)CCN1C(=O)OC(C)(C)C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070173526A1,CC[C@H]1C[C@@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(CCNC(=O)OC(C)(C)C)n2)c2nc(C(F)(F)F)ccc2N1C(=O)OC(C)C>>CC[C@H]1C[C@@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(CCN)n2)c2nc(C(F)(F)F)ccc2N1C(=O)OC(C)C,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20050038089A1,CC(C)(C)OC(=O)NCc1cccc(N)c1.O=C(N=C=S)c1ccccc1>>CC(C)(C)OC(=O)NCc1cccc(NC(N)=S)c1,,C1CCOC1,O,CO,O=C([O-])[O-].[K+].[K+],test
US06011028,BrCCC1OCCO1.COC(=O)C1CCCCC1=O>>COC(=O)C1(CCC2OCCO2)CCCCC1=O,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100216810A1,N#Cc1cc([N+](=O)[O-])ccc1Oc1cc(NC(=O)C(F)(F)F)c(F)cc1Cl>>N#Cc1cc(N)ccc1Oc1cc(NC(=O)C(F)(F)F)c(F)cc1Cl,,CC(=O)O,,C1CCOC1,,test
US20030125550A1,Nc1ccccc1.O=[N+]([O-])c1ccc(O)cc1F>>O=[N+]([O-])c1ccc(O)cc1Nc1ccccc1,,CCOC(C)=O,,,,test
US20110112293A1,O=Cc1ccc(S(=O)(=O)Cl)cc1.OCCOc1ccccc1>>O=Cc1ccc(S(=O)(=O)OCCOc2ccccc2)cc1,,O,c1ccncc1,,,test
US04410534,Cc1cc2n(c1)C(C(=O)c1cccn1C)CCC2C(=O)OC(C)C>>Cc1cc2n(c1)C(C(=O)c1cccn1C)CCC2C(=O)O,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US05977025,CC1=C(c2ccccc2)C(=O)N(C(C)(C)C(=O)O)CO1.Nc1ccccc1>>CC1=C(c2ccccc2)C(=O)N(C(C)(C)C(=O)Nc2ccccc2)CO1,,ClC(Cl)(Cl)Cl,ClCCl,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040019098A1,CCCC(=O)Cl.Nc1ccc2c(c1)C(=C1C(=O)Nc3ccccc31)OC2>>CCC(C(N)=O)c1ccc2c(c1)C(=C1C(=O)Nc3ccccc31)OC2,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20060111446A1,CC(C)c1ccc(CCNC(=O)OC(C)(C)C)c(N)c1.CCOC(=O)C(=O)Cl>>CCOC(=O)C(=O)Nc1cc(C(C)C)ccc1CCNC(=O)OC(C)(C)C,,CCOC(C)=O,ClCCl,O,c1ccncc1,test
US04594442,BrCCCOCCCBr.COC(=O)COc1ccc2ccc(O)c(C(C)=O)c2c1>>COC(=O)COc1ccc2ccc(OCCCOCCCBr)c(C(C)=O)c2c1,,CN(C)C=O,,[H-].[Na+],,test
US20070105831A1,C=CCBr.COc1cc(C(=O)O)ccc1Cl>>C=CCOC(=O)c1ccc(Cl)c(OC)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080249138A1,CCOC(=O)c1cccc(Cc2cc(Cl)ccc2O)n1.Clc1ccccc1CBr>>CCOC(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccccc2Cl)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070179196A1,CC(C)n1c(C(=O)N(C)C)c2c(c(O)c1=O)C(=O)N(Cc1ccc(F)c(Cl)c1)CC2>>CC(C)n1c(C(=O)N(C)C)c2c(c(O)c1=O)C(=O)N(Cc1ccc(F)cc1)CC2,[Pd],CO,,[H][H],,test
US20110250237A1,Cc1ccc(C#Cc2cnc3c(N)nc4ccccc4c3c2)c(C)c1>>Cc1ccc(CCc2cnc3c(N)nc4ccccc4c3c2)c(C)c1,[Pd],ClCCl,,CCO,[H][H],test
US20160159747A1,CCOC(=O)/C(=C/c1cnc(C)n1Cc1ccccc1)CC(=O)O.O=C(OC(=O)c1ccccc1)c1ccccc1>>CCOC(=O)c1cc(OC(=O)c2ccccc2)c2nc(C)n(Cc3ccccc3)c2c1,,CC#N,,,,test
US20100152213A1,Nc1ccc(Br)cc1C(=O)O.S=C=Nc1ccccc1Br>>O=c1c2cc(Br)ccc2[nH]c(=S)n1-c1ccccc1Br,,CCO,,,,test
US20160009645A1,CC(=O)Cl.Cl.c1cc(OC2CCNCC2)ccc1OCCCN1CCCCC1>>CC(=O)N1CCC(Oc2ccc(OCCCN3CCCCC3)cc2)CC1.Cl,,CCN(CC)CC,,Cl,ClCCl,test
US20150210720A1,CCOc1nc(N2CCN(C(C)=O)CC2)ccc1N.O=C(O)c1coc2c1C(=O)NCC2>>CCOc1nc(N2CCN(C(C)=O)CC2)ccc1NC(=O)c1coc2c1C(=O)NCC2,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US20160096841A1,Nc1c(F)cc(C(F)(F)F)cc1Cl.S=C(Cl)Cl>>Fc1cc(C(F)(F)F)cc(Cl)c1N=C=S,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070299062A1,CCNCC.CS(=O)(=O)Cc1ccc2c(c1)CC[C@H](n1cnc3cc(-c4ccc(Cl)cc4)sc3c1=O)C2>>CCN(CC)Cc1ccc2c(c1)CC[C@H](n1cnc3cc(-c4ccc(Cl)cc4)sc3c1=O)C2,,CN(C)C=O,,,,test
US04963568,CCOC(=O)C=CC1CCCCC1.COc1cccc(C2SCCCS2)c1OC>>COc1ccc2c(c1OC)CC(C1CCCCC1)CC2=O,[Ni],,,[Na+].[OH-],,test
US05025031,COc1cccc(Br)c1.Cc1ncc[nH]1>>Cc1nccn1-c1cccc(O)c1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US04496572,CN(C)CC1CCc2ccc(Br)cc2C1=O.c1c[nH]cn1>>O=C1c2cc(Br)ccc2CCC1Cc1ncc[nH]1,,Cc1ccccc1C,,,,test
US20070066624A1,CC(C)C(N)=O.CCC(=O)C(Cl)C(=O)OC.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCc1nc(C(C)C)sc1C(=O)OC,,C1CCOC1,,,,test
US20070249580A1,COC(=O)C1CCCCN(Cc2ccccc2)C1=O>>OCC1CCCCN(Cc2ccccc2)C1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20020156081A1,COc1cc(-c2nn(CC3(O)CCN(C(=O)OC(C)(C)C)CC3)c3ncnc(N)c23)ccc1NC(=O)OCc1ccccc1>>COc1cc(-c2nn(CC3(O)CCN(C(=O)OC(C)(C)C)CC3)c3ncnc(N)c23)ccc1N,[Pd],C1CCOC1,CCO,,,test
US04322370,CC1(C)CC(c2ccc(Cl)c(Cl)c2)c2ccc(O)cc2C1=O.CN(C)CCCl>>CN(C)CCOc1ccc2c(c1)C(=O)C(C)(C)CC2c1ccc(Cl)c(Cl)c1.Cl,,Cc1ccccc1,,[H][H],[H-].[Na+],test
US20130317045A1,Cc1cc(Nc2nc(C(=O)c3ccc(F)cc3)nc3ccsc23)n[nH]1>>Cc1cc(Nc2nc(CO)nc3ccsc23)n[nH]1,,C1CCOC1,CO,[BH4-].[Na+],,test
US20120196851A1,CC(C)C(=O)N1CCN(C(=O)[C@@H]2CC[C@@H](CNC(=O)CC(N)c3ccccc3)CC2)CC1.CCOCC>>CC(C)C(=O)N1CCN(C(=O)[C@@H]2CC[C@@H](CN3C(=O)CC(c4ccccc4)NC3=O)CC2)CC1,,CC#N,,,,test
US20120010241A1,Cc1nn(-c2ccc(C#N)c(NCC(C)(C)O)c2)c2cccc(-c3cnc4ccccc4c3)c12.OO>>Cc1nn(-c2ccc(C(N)=O)c(NCC(C)(C)O)c2)c2cccc(-c3cnc4ccccc4c3)c12,,CS(C)=O,O,CCO,[Na+].[OH-],test
US20130225673A1,CC(=O)CCl.O=Cc1cc(F)ccc1O>>CC(=O)c1cc2cc(F)ccc2o1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100120763A1,Cc1c[nH]c(Br)n1.O=[N+]([O-])c1c(F)cc(C(F)(F)F)cc1F>>Cc1cn(-c2cc(C(F)(F)F)cc(F)c2[N+](=O)[O-])c(Br)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120157471A1,CC(=O)Cl.Cn1c(-c2nc(N3CCNCC3)ncc2Cl)nc2ccccc21>>CC(=O)N1CCN(c2ncc(Cl)c(-c3nc4ccccc4n3C)n2)CC1,,ClCCl,,CCN(CC)CC,CO,test
US20090047687A1,CC(N)C(=O)O.O=C(Cl)c1ccccc1>>C[C@H](NCc1ccccc1)C(=O)O,,O,,Cl,[Na+].[OH-],test
US20090018103A1,CC(=O)NCCO[C@@H](c1cccc(Cl)c1F)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1>>CC(=O)NCCO[C@@H](c1cccc(Cl)c1F)[C@@H]1CCCNC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20140275118A1,CC(C)(C)OC(=O)N1C[C@H]2C[C@@H](Oc3ccc(C(F)(F)F)cn3)[C@@H]1C2>>FC(F)(F)c1ccc(O[C@@H]2C[C@@H]3CN[C@H]2C3)nc1,,C1COCCO1,CCOC(C)=O,Cl,,test
US20080153805A1,CCOC(=O)Cc1csc(N)n1.Cc1cc(C)cc(S(=O)(=O)N2CCc3ccc(C(=O)O)cc32)c1>>CCOC(=O)Cc1csc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cc(C)cc(C)c2)CC3)n1,CN(C)c1ccncc1,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06329381B1,CCC(C)N.Nc1nc(Cl)nc2c1ncn2Cc1ccccc1>>CCC(C)Nc1nc(N)c2ncn(Cc3ccccc3)c2n1,,CCCCO,,[Na+].[OH-],,test
US20150210697A1,CC(=O)Cl.COc1ccc(CN(c2nc(Nc3cc(C#N)cc(N4CCN(C5CNC5)CC4)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1>>COc1ccc(CN(c2nc(Nc3cc(C#N)cc(N4CCN(C5CN(C(C)=O)C5)CC4)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1,,ClCCl,ClCCl,O=C([O-])O.[Na+],,test
US20060276508A1,CCOC(=O)c1ccc(I)c(OCC)c1.OB(O)c1ccc(C(F)(F)F)cc1>>CCOC(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)c(OCC)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20130102590A1,C1CCNC1.O=C1Cc2ccccc2C1>>c1ccc2c(c1)CC(N1CCCC1)C2,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20080261941A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CCOP(=O)(Cc1cc(Br)cc(Oc2ccc(C(F)(F)F)cn2)c1)OCC>>CC(C)(C)OC(=O)N1CCC(=Cc2cc(Br)cc(Oc3ccc(C(F)(F)F)cn3)c2)CC1,,C1CCOC1,,[H-].[Na+],,test
US20100125062A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1CCC(c2cccnc2F)C1>>CC(=O)N1CCC(c2cccnc2F)C1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20040147615A1,CCCCCCCCCCCCCCC[C@@H](O)[C@H](C)N.O=C(n1ccnc1)n1ccnc1>>CCCCCCCCCCCCCCC[C@H]1OC(=O)N[C@H]1C,,ClCCl,,CCN(CC)CC,,test
US20060293379A1,NC1CCCCC1.O=Cc1ccc([N+](=O)[O-])cc1>>O=[N+]([O-])c1ccc(CNC2CCCCC2)cc1,CC(=O)O,ClCCl,,[Na+].[OH-],,test
US20040082611A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C(c1ncc(-c2ccncc2)cn1)N1CCN(S(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)CC1>>O=S(=O)(c1cc2cc(Cl)ccc2[nH]1)N1CCN(C(=S)c2ncc(-c3ccncc3)cn2)CC1,,Cc1ccccc1,,COCCOC,,test
US20150353507A1,Clc1cccc(-c2nc(Cl)c3c(n2)CCC3)c1.Nc1ccc(CC(=O)O)cc1>>O=C(O)Cc1ccc(Nc2nc(-c3cccc(Cl)c3)nc3c2CCC3)cc1,Cl,CN(C)C=O,,,,test
US04859229,CC(C)Oc1cc(NC(N)=O)c(F)cc1Cl.CCOC(=O)C1CCCC1=O>>CCOC(=O)C1=C(NC(=O)Nc2cc(OC(C)C)c(Cl)cc2F)CCC1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05567704,C1CCOC1.CC1(O)CCC2CC1(OB(O)CCCC[C@H](Cl)Br)C2(C)C.C[Mg]Br>>CC1(O)CCC2CC1(O)C2(C)C.C[C@H](CCCCBr)B([O-])[O-],,C1CCOC1,,[Cl-].[NH4+],,test
US20160237091A1,CC(=O)Nc1cc2c(cc1C=O)c(-c1ccnc(C)c1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1.O=[Cr](=O)=O>>CC(=O)Nc1cc2c(cc1C(=O)O)c(-c1ccnc(C)c1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1,,CC(C)=O,,O=S(=O)(O)O,,test
US20150361100A1,Cc1ccc2cc(CO)c(-c3ccccn3)n2c1>>Cc1ccc2cc(C=O)c(-c3ccccn3)n2c1,O=[Mn]=O,,,,,test
US20090181942A1,CCOC(=O)C(C)(C)Br.COc1ccc(Cn2nnnc2S)cc1>>CCOC(=O)C(C)(C)Sc1nnnn1Cc1ccc(OC)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20040019033A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N#Cc1c(F)cc(CN)cc1F>>CC(C)(C)OC(=O)NCc1cc(F)c(C#N)c(F)c1,,C1CCOC1,,,,test
US20130184222A1,COC(CN=C=O)OC.Cc1ccccc1C(C(=O)NC1CCCCC1)N(C(=O)CN)c1cccc(F)c1>>COC(CNC(=O)NCC(=O)N(c1cccc(F)c1)C(C(=O)NC1CCCCC1)c1ccccc1C)OC,,ClCCl,,CCN(CC)CC,,test
US05491144,COc1ccc(Nc2cc3c(cc2Nc2ccccc2)C(=O)NC3=O)cc1>>O=C1NC(=O)c2cc(Nc3ccc(O)cc3)c(Nc3ccccc3)cc21,,ClC(Cl)Cl,,BrB(Br)Br,,test
US20080280876A1,CCC(O)CC.N#Cc1ccc(O)c(Cl)c1>>CCC(CC)Oc1ccc(C#N)cc1Cl,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090264441A1,N#Cc1cc(Br)c(O)c(Br)c1.NO>>NC(=NO)c1cc(Br)c(O)c(Br)c1,,CCO,O,,,test
US20080004323A1,CCC(CC)C(C)SC(C#C[Si](C)(C)C)=Nc1ccccc1.Fc1ccc(S)cc1>>CCC(CC)C(C)SC(C=CSc1ccc(F)cc1)=Nc1ccccc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US03952001,C=CCN(CC=C)C(=O)Cl.CCCCCSc1nc[nH]n1>>C=CCN(CC=C)C(=O)n1cnc(SCCCCC)n1,,CCOCC,,C1CCOC1,CCN(CC)CC,test
US20090186886A1,CN(C)CCN.[O-][n+]1nc(Cl)nc2cc3c(cc21)CCCCC3>>CN(C)CCNc1nc2cc3c(cc2[n+]([O-])n1)CCCCC3,,COCCOC,,,,test
US20040236116A1,CCCCC=P(c1ccccc1)(c1ccccc1)c1ccccc1.COc1cc(OC)cc(C2(C=O)CCCC2)c1>>CCCCC=CC1(c2cc(OC)cc(OC)c2)CCCC1,,C1CCOC1,,,,test
US20030166644A1,COc1ccc(N)cn1.O=C(Cl)c1ccc(Cl)cc1>>O=C(Nc1ccc(O)nc1)c1ccc(Cl)cc1,,ClCCl,,,,test
US20120214840A1,CCOC(=O)c1cn2cc(C(C)(C)O[SiH2]C(C)(C)C)ccc2c1-c1ccc(F)cc1>>CCOC(=O)c1cn2cc(CO)ccc2c1-c1ccc(F)cc1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20160102071A1,Cc1cc(C(=O)O)ccc1-c1csc2ccc(CO)cc12.O=S1(=O)CCNCC1>>Cc1cc(C(=O)N2CCS(=O)(=O)CC2)ccc1-c1csc2ccc(CO)cc12,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04352817,CNCC(=O)O.O=c1[nH]c2cccc(I)c2c(=O)o1>>CN(CC(=O)O)C(=O)c1c(N)cccc1I,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US09212190B2,CN(C(=O)OC(C)(C)C)C1CCC(Oc2ncnc3sc4c(c23)[C@@H](C[C@H](O)C(N)=O)CC4)CC1>>CNC1CCC(Oc2ncnc3sc4c(c23)[C@@H](C[C@H](O)C(N)=O)CC4)CC1,,ClCCl,,Cl,,test
US05545662,CCCCCCC(=O)NC(CNC(=O)N[C@@H](CCCC(NC(=O)OC(C)(C)C)C(=O)O)C(=O)N[C@H](C)C(=O)O)C(=O)O>>CCCCCCC(=O)NC(CNC(=O)N[C@@H](CCCC(N)C(=O)O)C(=O)N[C@H](C)C(=O)O)C(=O)O,,O=C(O)C(F)(F)F,,,,test
US20150152097A1,CC(C)=CCCC(C)(O)Cn1nccc1C>>Cc1ccnn1CC1(C)CCCC(C)(C)O1,,O=CO,,,,test
US20140024650A1,COc1ccc(B(O)O)cc1F.Fc1ccc(Br)nc1>>COc1ccc(-c2ccc(F)cn2)cc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090318408A1,NC1=CCOC=C1.Nc1ccc(C(=O)On2nnc3ccccc32)cc1>>Nc1ccc(C(=O)NC2CCOCC2)cc1,,CN(C)C=O,,CCN(CC)CC,,test
US06239151B1,CC(C)CNNC(=O)[C@H](CC(C)C)[C@H](C/C=C/c1ccccc1)C(=O)NOC1CCCCO1>>CC(C)CNNC(=O)[C@H](CC(C)C)[C@H](CCCC1CCCCC1)C(=O)NOC1CCCCO1,O=[Pt],CC(=O)O,,,,test
US06355653B1,CCOC(=N)CS(=O)(=O)c1ccccc1.NNC(=O)c1cccs1>>N=C(CS(=O)(=O)c1ccccc1)NNC(=O)c1cccs1,,ClC(Cl)Cl,,Cl,[Na+].[OH-],test
US20110207711A1,CC(C)(C)OC(=O)Nc1cc(O)cn2nccc12.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)Nc1cc(OS(=O)(=O)C(F)(F)F)cn2nccc12,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20070043010A1,COC(=O)[C@H]1C[C@H](Oc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC)CN1C>>COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1O[C@H]1C[C@H](C(=O)O)N(C)C1,,C1CCOC1,CO,[Na+].[OH-],,test
US20030032834A1,CCN(C(=O)OC)c1ccc(C(CCN(Cc2ccccc2)C(=O)OC(C)(C)C)c2ccc(N(CC)C(=O)OC)cc2)cc1>>CCN(C(=O)OC)c1ccc(C(CCNCc2ccccc2)c2ccc(N(CC)C(=O)OC)cc2)cc1,,ClCCl,,C1COCCO1,Cl,test
US20150344423A1,CCOC(=O)c1cn(-c2cc(C(C)(C)C)cc(C3(C)CC3)c2)c(C(=O)C2CCCCC2)c1C>>Cc1c(C(=O)O)cn(-c2cc(C(C)(C)C)cc(C3(C)CC3)c2)c1C(=O)C1CCCCC1,,CS(C)=O,O,Cl,CC(C)(C)[O-].[K+],test
US20080045544A1,CCOc1cc(CN2CCC(N)CC2)ccc1OC.Fc1ccc2nc(Cl)ccc2c1>>CCOc1cc(CN2CCC(Nc3ccc4cc(F)ccc4n3)CC2)ccc1OC,,CC(=O)N(C)C,,,,test
US20150299192A1,Cn1ccc2c1CCN(C(=O)OC(C)(C)C)C2=O.O=C1CCC(=O)N1Br>>Cn1c(Br)cc2c1CCN(C(=O)OC(C)(C)C)C2=O,,C1CCOC1,CO,,,test
US20090281331A1,CC(C)(C)OC(=O)N1C[C@H]2[C@@H]([C@H]1C#N)C2(C)C.COC(C)(C)C>>CC(C)(C)OC(=O)N1C[C@H]2[C@@H](C1O)C2(C)C,,CCCCCCC,,,,test
US20090318385A1,COc1ccc(CO)c2c(C(=O)O)c(C3OCCO3)nn12>>COc1ccc(CO)c2cc(C3OCCO3)nn12,,Clc1ccccc1Cl,,,,test
US20150038438A1,COC(=O)C(C(=O)OC)C(=O)OC.COc1ccc(CN=C2CCCN(C)c3cc(Cl)ccc32)c(OC)c1>>COC(=O)c1c(O)c2c(n(Cc3ccc(OC)cc3OC)c1=O)-c1ccc(Cl)cc1N(C)CC2,,c1ccc(Oc2ccccc2)cc1,,,,test
US06350749B1,Cc1c2c(nn1CCc1ccccc1)CC(c1ccccc1Cl)CC2=O.Cl.N=C(N)NN>>Cc1c2c(nn1CCc1ccccc1)CC(c1ccccc1Cl)CC2=NNC(=N)N.Cl,,CCO,,Cl,O,test
US20140187553A1,COc1ccc(CNc2nnc(-c3ccc4c(c3)c(-c3nccc(Cl)n3)cn4S(=O)(=O)c3ccc(C)cc3)o2)cc1.OB(O)c1ccccc1F>>COc1ccc(CNc2nnc(-c3ccc4c(c3)c(-c3nccc(-c5ccccc5F)n3)cn4S(=O)(=O)c3ccc(C)cc3)o2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20090054435A1,COc1ccc(C(=O)c2cccc(OCc3nc(-c4ccccc4)oc3C)c2)c(O)c1.C[Mg]Br>>COc1ccc(C(C)(O)c2cccc(OCc3nc(-c4ccccc4)oc3C)c2)c(O)c1,,C1CCOC1,,CCOC(C)=O,,test
US20080058327A1,C=C(C(=O)OC)c1ccc(Cl)cc1.O=C(OO)c1cccc(Cl)c1>>COC(=O)C1(c2ccc(Cl)cc2)CO1,,ClC(Cl)Cl,,,,test
US04247710,Oc1ccc(OCc2ccccc2)cc1.c1ccc(COC[C@@H]2CO2)cc1>>Oc1ccccc1OCc1ccccc1,,CS(C)=O,,O,[Na+].[OH-],test
US04604390,CCN(CC)CCn1nc2c3c(c([N+](=O)[O-])ccc31)Oc1ccccc1-2>>CCN(CC)CCn1nc2c3c(c(N)ccc31)Oc1ccccc1-2,[Pd],C1CCOC1,,[H][H],,test
US03993679,NC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>NC(=O)c1cc(N)cc(N)c1,[Pd],CCO,CCOC(C)=O,[H][H],,test
US20070082912A1,CC(=O)CCC(=O)c1cc(Cl)ccc1OCc1c(F)cccc1F.Nc1ccc(Cl)c(C(=O)O)c1>>Cc1ccc(-c2cc(Cl)ccc2OCc2c(F)cccc2F)n1-c1ccc(Cl)c(C(=O)O)c1,,CC#N,ClCCl,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120184566A1,COc1cc2c(cc1Br)C(C)(C)CC2>>CC1(C)CCc2cc(O)c(Br)cc21,,ClCCl,,BrB(Br)Br,,test
US04381311,C[Mg]Br.O=C(c1cc(-c2ccc(F)cc2)c(-c2ccc(F)cc2)s1)C(F)(F)C(F)(F)F>>CC(O)(c1cc(-c2ccc(F)cc2)c(-c2ccc(F)cc2)s1)C(F)(F)C(F)(F)F,,C1CCOC1,,,,test
US20140171315A1,C=Cc1cc(Cl)c(C(=O)OC)cc1OC>>C=Cc1cc(Cl)c(C(=O)O)cc1OC,,O,,CO,[Na+].[OH-],test
US04544654,CCCCCCCNCC.N#CCCl>>CCCCCCCN(CC)CC#N,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US05194628,C1CCOC1.CCCCCC.CN(C)CCN(C)C.FC1(F)Oc2ccccc2O1>>CCOC=C(C#N)C(=O)OCC,,CCCCCC,,[Li]CCCC,,test
US20050096389A1,C1CCOC1.CC(O)CCC(C)O.O.O=C(Cl)C=Cc1ccccc1.c1ccncc1>>CC(CCC(C)OC(=O)C=Cc1ccccc1)OC(=O)C=Cc1ccccc1,,O,,,,test
US20110092474A1,CCCCN.Fc1cc(Br)ccn1>>CCCCNc1cc(Br)ccn1,,CN1CCCC1=O,ClCCl,,,test
US20110152318A1,CCOCC.O=C1CCCc2c(O)cccc21>>C=C1CCCc2c(O)cccc21,,CCOCC,CCOCC,CC(C)(C)[O-].[K+],,test
US20100273781A1,O=C(Cn1ccc2ccncc21)OCc1ccccc1>>O=C(O)Cn1ccc2ccncc21,[Pd],CO,,[H][H],,test
US20110105470A1,NC1CCC2(CC1)CSC1=C(O2)c2ccccc2C(=O)C1=O.O=C(Cl)c1cccc(C(F)(F)F)c1>>O=C1C(=O)c2ccccc2C2=C1SCC1(CCC(NC(=O)c3cccc(C(F)(F)F)c3)CC1)O2,,CCN(CC)CC,,Cl,Cl,test
US06100283,CC(=O)O.Nc1cccc(C(=O)O)c1N>>Cc1nc2cccc(C(=O)O)c2[nH]1,,Cl,,,,test
US20140018533A1,CCO.CCOC(=O)C1=C(Nc2ccc(OCCN(C)C)cc2C)OCC1=O.O=Cc1c[nH]c2ncccc12>>CCOC(=O)C1=C(Nc2ccc(OCCN(C)C)cc2C)OC(=Cc2c[nH]c3ncccc23)C1=O.O=CO,,CCO,,C1CCNCC1,,test
US20120010207A1,CCc1cc(Cl)ccc1OC>>CCc1cc(Cl)ccc1O,,ClCCl,,BrB(Br)Br,CO,test
US20060211709A1,CNC(=O)c1nc(-c2cccc(C#N)c2)cnc1N.NO>>CNC(=O)c1nc(-c2cccc(C(=N)NO)c2)cnc1N,,CCO,O,,,test
US20100249439A1,CC(C)Cl.CCC(=O)c1ccc(C)o1>>CCC(=O)c1cc(C(C)C)c(C)o1,,[Na+],[OH-],[Al+3].[Cl-].[Cl-].[Cl-],,test
US20030013754A1,CCOC(=O)C(CC(=O)c1ccccc1)C(C)=O.Nc1ccc([N+](=O)[O-])cc1>>CCOC(=O)c1cc(-c2ccccc2)n(-c2ccc([N+](=O)[O-])cc2)c1C,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100204221A1,Clc1nc(Cl)c2cc[nH]c2n1.OB(O)c1ccc(F)c(Cl)c1>>Fc1ccc(-c2nc(Cl)nc3[nH]ccc23)cc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20100273806A1,CCNCC.FC(F)(F)c1cc(Cl)nc(Cl)c1>>CCN(CC)c1cc(C(F)(F)F)cc(Cl)n1,,CC(C)O,,CCN(C(C)C)C(C)C,O,test
US20140163000A1,O=[N+]([O-])c1cnccc1Cl.c1cn[nH]c1>>O=[N+]([O-])c1cnccc1-n1cccn1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140336177A1,CC(C)(C)OC(=O)N1CCN(CC(O)c2ccc3nonc3c2)[C@H](CO)C1>>CC(C)(C)OC(=O)N1CCN2CC(c3ccc4nonc4c3)OC[C@@H]2C1,,Cc1ccccc1,,CCCCP(=CC#N)(CCCC)CCCC,,test
US20030087936A1,Cc1cc(Cl)c(OCCCCCCBr)c(Cl)c1.O=C1NCCN1c1cccnc1>>Cc1cc(Cl)c(OCCCCCCN2CCN(c3cccnc3)C2=O)c(Cl)c1,,CN(C)C=O,,[H-].[Na+],,test
US20060025474A1,CCOC(=O)CCCS(=O)(=O)CCc1ccc(C(CC)(CC)c2ccc(CCC(O)C(C)(C)C)c(C)c2)cc1C>>CCC(CC)(c1ccc(CCC(O)C(C)(C)C)c(C)c1)c1ccc(CCS(=O)(=O)CCCC(=O)O)c(C)c1,,C1COCCO1,O,Cl,[Na+].[OH-],test
US20130296296A1,CC(=O)N1CCc2cc(C(=O)CBr)ccc21.CC(C)(C)OC(=O)N1CCNCC1>>CC(=O)N1CCc2cc(CCN3CCN(C(=O)OC(C)(C)C)CC3)ccc21,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080139639A1,CCOC(=O)c1cc(Br)n(S(=O)(=O)c2cccnc2)c1C.OB(O)c1ccccc1>>CCOC(=O)c1cc(-c2ccccc2)n(S(=O)(=O)c2cccnc2)c1C,,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US20160106102A1,CCc1cc(N)nn1Cc1ccccc1.O=C(O)c1cccnc1>>CCc1cc(NC(=O)c2cccnc2)nn1Cc1ccccc1,,C1COCCO1,,CCN=C=NCCCN(C)C,Cl,test
US04997986,BrCCCCCCOCCCCOc1ccc2ccccc2c1.NCc1ccccc1>>c1ccc(CNCCCCCCOCCCCOc2ccc3ccccc3c2)cc1,,O=C([O-])O,[Na+],,,test
US20100227866A1,CS(=O)(=O)NC1CCCCC1N1C(=O)c2ccccc2C(C(=O)NOCc2cccc(C(=O)O)c2)C1c1ccc(Cl)cc1Cl.CS(N)(=O)=O>>CS(=O)(=O)NC(=O)c1cccc(CONC(=O)C2c3ccccc3C(=O)N(C3CCCCC3NS(C)(=O)=O)C2c2ccc(Cl)cc2Cl)c1,,CCOC(C)=O,CN(C)C=O,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US20130123338A1,C#CCN(C)C.CCCCC/C=C\C/C=C\CCCCCCCCC(CCCCCCCC/C=C\C/C=C\CCCCC)N=[N+]=[N-]>>CCCCC/C=C\C/C=C\CCCCCCCCC(CCCCCCCC/C=C\C/C=C\CCCCC)n1cc(CN(C)C)nn1,,CC(C)(C)O,O,O=C(CO)O[CH][C@@H](O)CO,C[O-].[Na+],test
US20110003690A1,CC(=O)OCc1ccc(C(=S)NC[Si](C)(C)C)c2ccccc12.CI>>CS/C(=N\C[Si](C)(C)C)c1ccc(COC(C)=O)c2ccccc12,,C1CCOC1,COC(C)(C)C,CC(C)(C)[O-].[K+],,test
US20110160256A1,Cn1nccc1-c1csc(C(=O)O)n1.N[C@@H](Cc1cccc(F)c1)CN1C(=O)c2ccccc2C1=O>>Cn1nccc1-c1csc(C(=O)N[C@@H](Cc2cccc(F)c2)CN2C(=O)c3ccccc3C2=O)n1,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20050070542A1,COB(OC)OC.COc1cc(OC(F)(F)F)ccc1Br>>COc1cc(OC(F)(F)F)ccc1B(O)O,,C1CCOC1,,Cl,[Li]CCCC,test
US05037834,C=O.NCCc1csc(Nc2cccnc2)n1>>c1cncc(Nc2nc3c(s2)CNCC3)c1,,CO,,CC(=O)O,,test
US20080171756A1,CC(C)(C)c1ccc(B(O)O)cc1.CC(C)(C)c1ccc(Cn2c(-c3ccccc3Br)nc(O)c(C(=O)NCC(=O)O)c2=O)cc1>>CC(C)(C)c1ccc(Cn2c(-c3ccccc3-c3ccc(C(C)(C)C)cc3)nc(O)c(C(=O)NCC(=O)O)c2=O)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20110263562A1,CC(=O)OC(C)=O.CC(N)CO[C@@H]1CC[C@@H](c2nc3ccc(OCC4CC4)cc3o2)CC1>>CC(=O)NC(C)CO[C@@H]1CC[C@@H](c2nc3ccc(OCC4CC4)cc3o2)CC1,,c1ccncc1,,,,test
US04205085,O=C(Cl)c1ccc(N(CCCCCCCCCCCCCCCC(F)(F)F)C(=O)OCc2ccccc2)cc1.O=C(O)CC(O)C(=O)O>>O=C(O)CC(O)C(=O)OC(=O)c1ccc(NCCCCCCCCCCCCCCCC(F)(F)F)cc1,[Pd],C1CCOC1,CCOCC,CCN(CC)CC,[H][H],test
US20130245254A1,Cc1cc(B2OC(C)(C)C(C)(C)O2)cc([N+](=O)[O-])c1N>>Cc1cc(B2OC(C)(C)C(C)(C)O2)cc(N)c1N,[Pd],CO,,,,test
US20090186871A1,C1COCCN1.CC(C)(C)OC(=O)N1CCN(CCC=O)C(=O)C1>>CC(C)(C)OC(=O)N1CCN(CCCN2CCOCC2)C(=O)C1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05102443,O=C=NS(=O)(=O)Cl.Oc1ccccc1OCCCl>>O=C=NS(=O)(=O)Oc1ccccc1OCCCl,,Cc1ccccc1C,,,,test
US20150291572A1,CS(=O)(=O)Cl.OC1CCOC(c2cncc(C(F)(F)F)c2)C1>>CS(=O)(=O)OC1CCOC(c2cncc(C(F)(F)F)c2)C1,,ClCCl,,,,test
US20040204409A1,COCOc1ccc(C(=O)NCc2ccc3cnc(CCc4ccccc4)n3c2)cc1>>O=C(NCc1ccc2cnc(CCc3ccccc3)n2c1)c1ccc(O)cc1,,CO,Cl,,,test
US20140179699A1,BrCCBr.Oc1cc(Cl)ccc1Br>>Clc1ccc(Br)c(OCCBr)c1,,O,,[Na+].[OH-],,test
US20140200227A1,CC1(NC(=O)OC(C)(C)C)CCCNC1.O=[N+]([O-])c1cnc2c(c1Cl)CCC2>>CC1(NC(=O)OC(C)(C)C)CCCN(c2c([N+](=O)[O-])cnc3c2CCC3)C1,,CC(C)O,,CCN(CC)CC,,test
US20020156081A1,CC1(C)OB(c2ccc(Nc3ccccc3)cc2)OC1(C)C.CN1CCN([C@H]2CC[C@@H](n3nc(I)c4c(N)ncnc43)CC2)CC1>>CN1CCN(C2CCC(n3nc(-c4ccc(Nc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20110311474A1,CCC1CC(OC2CCOCC2)CC1(CC)C(=O)O>>CCC1CC(OC2CCOCC2)CC1C(=O)O,,C1COCCO1,,[Na+].[OH-],,test
US20060046980A1,COCOc1ccc(Cc2cc(C)c(O)cc2C)cc1C(C)C.II>>COCOc1ccc(Cc2cc(C)c(O)c(I)c2C)cc1C(C)C,,CCO,O,CN,,test
US20080103156A1,O=C(O)/C=C/c1cccc(F)c1F>>O=C(O)CCc1cccc(F)c1F,[Pd],CCOC(C)=O,,,,test
US05104994,N#CSCc1ccccc1.N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(Br)c1S(=O)(=O)C(F)(F)F>>N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(SCc2ccccc2)c1S(=O)(=O)C(F)(F)F,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20140343000A1,C=C(C)[C@@H]1CC[C@]2(N)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CC(C)(C)OC(=O)NCC=O>>C=C(C)[C@@H]1CC[C@]2(NCCNC(=O)OC(C)(C)C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,CC(C)O[Ti](OC(C)C)(OC(C)C)OC(C)C,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20110144110A1,CCOC(=O)CCc1ccc(-c2ccc(-n3ccnc3)cc2)n1-c1ccc(C#N)cc1C>>CCOC(=O)CCc1ccc(-c2ccc(-n3ccnc3)cc2)n1-c1ccc(CN)cc1C,,CO,,Cl,[BH4-].[Na+],test
US20090325953A1,O=C(c1c[nH]c(C(=O)N(Cc2cn3ccc(C(F)(F)F)cc3n2)CC2OCCO2)c1)c1c(F)cc(F)cc1F>>O=C(c1c(F)cc(F)cc1F)c1c[nH]c2c(=O)n(Cc3cn4ccc(C(F)(F)F)cc4n3)ccc12,,CS(=O)(=O)O,,CC#N,O,test
US20140275179A1,O=C1CCC(=O)N1Cl.OCc1sccc1-c1ccc(Cl)cc1>>OCc1sc(Cl)cc1-c1ccc(Cl)cc1,,CN(C)C=O,,,,test
US05064844,CI.OCc1cnn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)n1>>COCc1cnn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)n1,,C1CCOC1,,O,[H-].[Na+],test
US20020032184A1,Cc1n[nH]c(C)c1Cc1cc(Cl)cc(Cl)c1.NCCCl>>Cc1nn(CCN)c(C)c1Cc1cc(Cl)cc(Cl)c1,,Cc1ccccc1,ClCCl,Cl,,test
US20130137675A1,C#Cc1ccnn1-c1ccccc1.O=CC#Cc1ccccc1>>OC(C#Cc1ccccc1)C#Cc1ccnn1-c1ccccc1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20010014684A1,COCCOCN(c1noc(C)c1Cl)S(=O)(=O)c1c(Cc2cc3c(cc2C)OCO3)sc2ncccc12>>Cc1cc2c(cc1Cc1sc3ncccc3c1S(=O)(=O)Nc1noc(C)c1Cl)OCO2,,CO,,Cl,,test
US20100210671A1,CCC1(c2ccccc2)c2cc(Cl)ccc2N(Cc2ccncc2)C(=O)N1CC(F)(F)F.O=C(OO)c1cccc(Cl)c1>>CCC1(c2ccccc2)c2cc(Cl)ccc2N(Cc2cc[n+]([O-])cc2)C(=O)N1CC(F)(F)F,,ClCCl,,,,test
US04277479,ICCCc1nnnn1Cc1ccccc1.O=c1ccc2cc(O)ccc2[nH]1>>O=c1ccc2cc(OCCCc3nnnn3Cc3ccccc3)ccc2[nH]1,,CCO,,,,test
US04634710,COc1c(C)cnc(CCl)c1C.Sc1nc2cc3c(cc2[nH]1)OCO3>>COc1c(C)cnc(CSc2nc3cc4c(cc3[nH]2)OCO4)c1C,,O,,Cl,[Na+].[OH-],test
US20160176891A1,COc1ccc2c(c1)CCN2.Cc1nc(Cl)c2cc(C)oc2n1>>COc1ccc2c(c1)CCN2c1nc(C)nc2oc(C)cc12,Cl,CCCCO,,,,test
US04808729,COC(=O)CCCC(C)=O.OCC(S)CS>>COC(=O)CCCC1(C)OCC(CS)S1,,ClCCl,,CCOCC,FB(F)F,test
US06410592B1,C=O.Cl.NCCc1ccccc1.O=C1CCCc2cc(F)ccc21>>Cl.O=C1c2ccc(F)cc2CCC1CNCCc1ccccc1,,CCO,,,,test
US20110015157A1,BrCc1ccccc1.C=CC[C@]1(c2ccc(F)cc2)CCN([C@H]2CCCNC2)C(=O)O1>>C=CC[C@]1(c2ccc(F)cc2)CCN([C@H]2CCCN(Cc3ccccc3)C2)C(=O)O1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140155391A1,CC#N.CO/N=C\c1ccc(C(=O)O)cc1OCC1CC1>>CO/N=C\c1ccc(C(=O)OC)cc1OCC1CC1,,CC#N,,O=C(n1ccnc1)n1ccnc1,,test
US20130131040A1,N#Cc1ncc(N[C@H](Cc2ccccc2)C(N)=O)nc1Nc1ccc2ncccc2c1.OO>>NC(=O)c1ncc(N[C@H](Cc2ccccc2)C(N)=O)nc1Nc1ccc2ncccc2c1,,CCO,CS(C)=O,CC(=O)O,[Na+].[OH-],test
US05519016,COc1cc(OC)nc(S(C)(=O)=O)n1.c1ccc(CN2CCNCC2)cc1>>COc1cc(OC)nc(N2CCN(Cc3ccccc3)CC2)n1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080096877A1,CCOC(=O)C1Cc2cc(OCCOC)cc(N(C3CC3)S(=O)(=O)c3ccccn3)c2N1C(=O)OC(C)(C)C>>CCOC(=O)C1Cc2cc(OCCOC)cc(N(C3CC3)S(=O)(=O)c3ccccn3)c2N1,,CCOC(C)=O,Cl,,,test
US05539112,CC(=O)N(CCCN(C)C)c1ccc(-c2cc(=O)c3c(N)c(F)cc(F)c3o2)cc1F.CCCCCI>>CCCCCNc1c(F)cc(F)c2oc(-c3ccc(N(CCCN(C)C)C(C)=O)c(F)c3)cc(=O)c12,,CN(C)C=O,,O,[H-].[Na+],test
US20030232818A1,COc1ccc(Cn2cc(C(=O)O)c(=O)c3c(C)c(F)c(N4CC[C@@H](NC(=O)OC(C)(C)C)C4)nc32)c(OC)c1>>Cc1c(F)c(N2CC[C@@H](N)C2)nc2[nH]cc(C(=O)O)c(=O)c12,,O=C(O)C(F)(F)F,,,,test
US20120202785A1,CO[C@@H]1C[C@H](N)C1.O=[N+]([O-])c1ccc(F)cc1F>>CO[C@@H]1C[C@H](Nc2cc(F)ccc2N)C1,[Pd],CC#N,,CCN(C(C)C)C(C)C,,test
US05739333,Cc1ccc(-c2c(Cl)ncnc2Cl)cc1.OCCO>>Cc1ccc(-c2c(Cl)ncnc2OCCO)cc1,,CC(=O)O,,C1CCOC1,[H-].[Na+],test
US20150252057A1,CC(C)N1CC2CN(C(=O)OC(C)(C)C)CCN2C1=O>>CC(C)N1CC2CNCCN2C1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US04980470,CCNCC1CCNC1.COc1c(F)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12>>CCNCC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2OC)C1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20080255113A1,CCOC(=O)c1cc2c(C)cccc2n(C(C)C)c1=O>>Cc1cccc2c1cc(C(=O)O)c(=O)n2C(C)C,,CCO,,Cl,[Na+].[OH-],test
US20050282858A1,CN[C@H]1CCCC[C@@H]1NC.O=C1OC2(CCN(C(=O)C3(c4ccc(Br)cc4)CC3)C2)c2ccncc21.c1c[nH]cn1>>O=C1O[C@]2(CCN(C(=O)C3(c4ccc(-n5cnc6ccccc65)cc4)CC3)C2)c2ccncc21,[Cu]I,,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20050153959A1,Cc1cc(C[C@@H](OC(=O)N2CCC(c3cc4ccccc4[nH]c3=O)CC2)C(=O)O)cc2cn(COCC[Si](C)(C)C)nc12.NC(=NO)c1ccc(F)cc1>>Cc1cc(C[C@@H](OC(=O)N2CCC(c3cc4ccccc4[nH]c3=O)CC2)c2nc(-c3ccc(F)cc3)no2)cc2cn(COCC[Si](C)(C)C)nc12,,COCCOCCOC,,CCN=C=NCCCN(C)C,Cl,test
US20070161665A1,CCn1c(-c2nonc2NC(=O)OC(C)(C)C)nc2cncc(OC3CCN(C(=O)OC(C)(C)C)CC3)c21>>CCn1c(-c2nonc2N)nc2cncc(OC3CCNCC3)c21,,ClCCl,,O=C(O)C(F)(F)F,,test
US05356749,CC(C)c1cccc(C(C)C)c1NC(=N)Nc1c(C(C)C)cccc1C(C)C.Cc1ccc(C(Cl)Cl)cc1>>CC(C)c1cccc(C(C)C)c1NC(=NCc1ccc(CCl)cc1)Nc1c(C(C)C)cccc1C(C)C,,Cc1ccccc1C,,O=C([O-])[O-].[K+].[K+],,test
US07597875B2,N.O=C1c2ccccc2C(=O)C1(O)O>>NC(=O)c1ccccc1,,CO,,ClCCl,,test
US05270313,BrP(Br)Br.OCc1ccccc1C(F)(F)F>>FC(F)(F)c1ccccc1CBr,,Cc1ccccc1,,,,test
US06177452B1,Cc1ccc(S)cc1.O=C(O)CCc1oc(Cl)nc1-c1ccc(Cl)cc1>>Cc1ccc(Sc2nc(-c3ccc(Cl)cc3)c(CCC(=O)O)o2)cc1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US05763450,COCOc1cc2c(OCOC)cccc2cc1C#Cc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC>>COc1cc(Cc2cnc(N)nc2N)cc(C#Cc2cc3cccc(O)c3cc2O)c1OC,,C1CCOC1,,Cl,O,test
US06037367,CC(=O)OC(C)=O.COc1ccc(C(C#Cc2ccccc2)CN)cc1OC1CCCC1>>COc1ccc(C(C#Cc2ccccc2)CNC(C)=O)cc1OC1CCCC1,,CCOC(C)=O,,CCN(CC)CC,CO,test
US20040127574A1,CC(C)Oc1cccc(CC(C(=O)O)C(O)c2ccc(F)cc2)c1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)Oc1cccc(CC2NC(=O)OC2c2ccc(F)cc2)c1,,C1CCOC1,,CCN(CC)CC,,test
US06689922B1,CC(C)(CCCCc1cccc(C=Cc2ccc(CO)c(CO)c2)c1)OC1CCCCO1>>CC(C)(O)CCCCc1cccc(C=Cc2ccc(CO)c(CO)c2)c1,,C1CCOC1,O,O=S(=O)(O)O,,test
US20100267712A1,CI.O=[N+]([O-])c1ccc2c(c1)CCCN2>>CN1CCCc2cc([N+](=O)[O-])ccc21,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20090286261A1,CC(C)(C)OC(=O)NCCN.N#Cc1cccc(S(=O)(=O)Cl)c1>>CC(C)(C)OC(=O)NCCNS(=O)(=O)c1cccc(C#N)c1,,C1COCCO1,,CCN(CC)CC,,test
US20150141400A1,CC(C)(C)OC(=O)NCC(=O)O.CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(CN3CCNCC3)c(C(F)(F)F)cc2c1=O>>CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(CN3CCN(C(=O)CN)CC3)c(C(F)(F)F)cc2c1=O,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160168139A1,ICCOCCI.N[C@@H]1CCCC[C@H]1Nc1ccc2c(c1)Sc1cccc(Br)c1S2>>Brc1cccc2c1Sc1ccc(N[C@@H]3CCCC[C@H]3N3CCOCC3)cc1S2,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20100249085A1,CC(C)(O)c1ccc(C#N)cc1.CCN(CC)S(F)(F)F>>CC(C)(F)c1ccc(C#N)cc1,,ClCCl,O,,,test
US05998412,CC(C)[C@@H](NS(=O)(=O)N1CCC(Oc2ccc(Cl)cn2)CC1)C(=O)O.C[Si](C)(C)NO[Si](C)(C)C>>CC(C)[C@@H](NS(=O)(=O)N1CCC(Oc2ccc(Cl)cn2)CC1)C(=O)NO,,ClCCl,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20150353581A1,CC(N)(C#N)COc1c(F)c(F)c2c(c1Cl)B(O)OC2.O=C(O)c1ccc(OC(F)(F)F)cc1>>CC(C#N)(COc1c(F)c(F)c2c(c1Cl)B(O)OC2)NC(=O)c1ccc(OC(F)(F)F)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04921851,CC(=O)NCCS.Clc1ccc2nccn2n1>>CC(=O)NCCSc1ccc2nccn2n1,,CCO,,[H-].[Na+],,test
US20120238541A1,Cc1nn(C)c(C)c1-c1nccc2c(=O)c(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)oc12.Cl>>Cl.NC1(c2ccc(-c3c(-c4ccccc4)oc4c(-c5cccnc5)nccc4c3=O)cc2)CCC1,,C1COCCO1,,,,test
US20150361065A1,COc1ccc2c(Oc3ccc(/C=C/C(C)=O)cc3)c(-c3ccccc3C(C)C)sc2c1>>CC(=O)/C=C/c1ccc(Oc2c(-c3ccccc3C(C)C)sc3cc(O)ccc23)cc1,,ClCCl,,BrB(Br)Br,,test
US20010041700A1,C1COCCN1.COC(=O)[C@@H](CC(=O)O)CC1CCCCC1>>COC(=O)[C@@H](CC(=O)N1CCOCC1)CC1CCCCC1,,CCOC(C)=O,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
US20100331320A1,C=CC(=O)c1ccccc1F.C[C@H](N)c1ccc(Br)cc1>>C[C@H](NCCC(=O)c1ccccc1F)c1ccc(Br)cc1,,CC#N,,,,test
US04962103,CC(=O)S[C@H]1C[C@@H](CC(=O)O)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1.CN(C)C=O>>CC(=O)S[C@H]1C[C@@H](CC(=O)N(C)C)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US06307056B1,O=C1Nc2ccc(F)c(I)c2/C1=C/c1ccc[nH]1.OB(O)c1ccc(O)cc1>>O=C1Nc2ccc(F)c(-c3ccc(O)cc3)c2/C1=C/c1ccc[nH]1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20120040984A1,CCOC(=O)[C@@H]1CC[C@@H](Nc2ccc(C(=O)Nc3nnc(Cc4ccccc4)s3)cc2)CC1>>O=C(Nc1nnc(Cc2ccccc2)s1)c1ccc(N[C@@H]2CC[C@@H](C(=O)O)CC2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US05789405,CCOC(=O)COC1CCC2(CO2)C(C2(C)OC2CC=C(C)C)C1OC>>COC1C(OCC(=O)O)CCC2(CO2)C1C1(C)OC1CC=C(C)C,,CCO,,Cl,[Na+].[OH-],test
US20160122342A1,CCN(c1cccc2c1CC=CCCc1cc(C)nc(OC)c1CNC2=O)[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1>>CCN(c1cccc2c1CC=CCCc1cc(C)[nH]c(=O)c1CNC2=O)[C@@H]1CC[C@@H](N)CC1,,C1COCCO1,CO,Cl,,test
US20040204427A1,CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@H](N2C(=O)c3ccccc3C2=O)C1>>CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@H](N)C1,,C1CCOC1,CCO,NN,,test
US20070232627A1,CC(C)c1ccc(C#N)c(N=CN(C)C)n1.Nc1cc(C(=O)Nc2ccc(Br)cn2)ccc1Sc1ccc(NC(=O)OCC(Cl)(Cl)Cl)cc1>>CC(C)c1ccc2c(Nc3cc(C(=O)Nc4ccc(Br)cn4)ccc3Sc3ccc(NC(=O)OCC(Cl)(Cl)Cl)cc3)ncnc2n1,,CC(=O)O,,,,test
US20130203755A1,Cc1[nH]c2ncc(Br)cc2c1C(=O)CCl.NC(N)=S>>Cc1[nH]c2ncc(Br)cc2c1-c1csc(N)n1,,CCO,,,,test
US05073565,CC(C)c1cccc(C(C)C)c1N=C=O.CCCCCCCCCCCCn1nnnc1N>>CCCCCCCCCCCCn1nnnc1NC(=O)Nc1c(C(C)C)cccc1C(C)C,,CC#N,,CCN(CC)CC,,test
US20130137672A1,CC#N.Cc1cc(C)nc(Cl)n1.Cc1noc(-c2ccccc2C(=O)N2C[C@H]3CCNC[C@H]32)n1>>Cc1noc(-c2ccccc2C(=O)N2C[C@H]3CCN(c4cc(N(C)C)ncn4)C[C@H]32)n1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20040077728A1,CCC/C=C/[C@H](O)OC1CCCCO1>>CCCCC[C@H](O)OC1CCCCO1,[Pd],CCO,,[H][H],,test
US20090163464A1,C1CCNC1.Cn1cc(-c2ccc3nc(N4CC(=O)C4)sc3c2)cn1>>Cn1cc(-c2ccc3nc(N4CC(N5CCCC5)C4)sc3c2)cn1,,Cc1ccccc1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090318429A1,CCOC(=O)C(N)=S.O=C(CBr)c1cc(Br)c(O)c(Br)c1>>CCOC(=O)c1nc(-c2cc(Br)c(O)c(Br)c2)cs1,,CCO,,,,test
US20130274253A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1c(N)cccc1F>>Cc1c(F)cccc1NC(=O)OC(C)(C)C,,C1CCOC1,,,,test
US20070179173A1,N#Cc1ccc2c(c1)c1ccccc1c(=O)n2Cc1ccccc1.O=CO>>O=Cc1ccc2c(c1)c1ccccc1c(=O)n2Cc1ccccc1,[Ni],,,,,test
US20120190673A1,O=C(c1ccc([N+](=O)[O-])c([N+](=O)[O-])c1)N1CCOCC1>>O=[N+]([O-])c1ccc(CN2CCOCC2)cc1[N+](=O)[O-],,CO,,,,test
US20050272761A1,CC(C)(C)[Si](C)(C)n1cc(Br)c2cc(-c3cccc(F)c3)cnc21.O=C=O>>CC(C)(C)[Si](C)(C)n1cc(C(=O)O)c2cc(-c3cccc(F)c3)cnc21,,C1CCOC1,,CCCCC,[Li]C(C)(C)C,test
US03989749,CCCCCC(CCCN(C#N)CCCCCC(C)C(=O)OCC)OC(C)=O>>CCCCCC(O)CCCN(C#N)CCCCCC(C)C(=O)O,,CCO,O,[Na+].[OH-],,test
US20080275029A1,CC(C)(C)OC(=O)N1CCC(CN)(c2ccc(Cl)cc2)CC1.O=c1[nH]cnc2cc(F)ccc12>>NCC1(c2ccc(Cl)cc2)CCN(c2ccc3c(=O)[nH]cnc3c2)CC1,,O,,,,test
US20110082181A1,C=CC(C)C(O)c1c(C)noc1-c1ccc(Br)cc1.CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1>>C=CC(C)C(O)c1c(C)noc1-c1ccc(-c2ccc(C3(C(=O)OCC)CC3)cc2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,,,test
US20030225111A1,COc1cc2c(NC(=S)Nc3c(C)cccc3C)ncnc2cc1OCC1CCN(C)CC1.N>>COc1cc2c(NC(=N)Nc3c(C)cccc3C)ncnc2cc1OCC1CCN(C)CC1,,CO,ClC(Cl)Cl,,,test
US20070248672A1,CNc1[nH]c2cc(OC)c(OC)cc2c1-c1ccc(OC)cc1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>COc1ccc(-c2c(CNC(c3ccccc3)(c3ccccc3)c3ccccc3)[nH]c3cc(OC)c(OC)cc23)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090036492A1,CC(=O)Oc1cc(C=O)c2ccccc2c1.COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>COc1cc(O)c2c(c1C(=O)NCc1cc(OC(C)=O)cc3ccccc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20060276469A1,CC(=O)CS(C)(=O)=O.Nc1ccc(Br)cc1C(=O)c1ccc(C(F)(F)F)cc1>>Cc1nc2ccc(Br)cc2c(-c2ccc(C(F)(F)F)cc2)c1S(C)(=O)=O,,CCO,,[Na],,test
US20100179211A1,CC(C)(C)OC(=O)N1CCC(O)(c2ccc(F)c(Cl)c2)C1>>OC1(c2ccc(F)c(Cl)c2)CCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20010039285A1,COc1ccc(C2c3ccc(OC)cc3CCN2c2ccccc2)cc1>>Oc1ccc(C2c3ccc(O)cc3CCN2c2ccccc2)cc1,,ClCCl,,BrB(Br)Br,,test
US05840726,C=CCBr.CC(C)(C)OC(=O)NCC(c1ccccc1)c1ccccc1>>C=CCN(CC(c1ccccc1)c1ccccc1)C(=O)OC(C)(C)C,,CCCCCC,CCOC(C)=O,C1CCOC1,[Li]CCCC,test
US20070259881A1,CC1(C)OC[C@@H](CNc2c(N)cnc3cc(Br)ccc23)O1.CCOCC(=O)Cl>>CCOCc1nc2cnc3cc(Br)ccc3c2n1C[C@@H]1COC(C)(C)O1,,ClCCl,,CCN(CC)CC,,test
US20020132810A1,CC(C)(F)CCC(CC(O[Si](C)(C)C(C)(C)C)C(Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)c1ncco1>>CC(C)(F)CCC(CC(O)C(Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)c1ncco1,,C1CCOC1,,,,test
US20090069302A1,CCc1cc(S(=O)(=O)Cl)ccc1OC.CNCCN(C)S(=O)(=O)c1ccc(OC)c(OC)c1>>CCc1cc(S(=O)(=O)N(C)CCN(C)S(=O)(=O)c2ccc(OC)c(OC)c2)ccc1OC,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20030114443A1,CC(=O)N1CCC(C(=O)Cl)CC1.c1ccc(CC2CCN(CCCNc3cccnc3)CC2)cc1>>CC(=O)N1CCC(C(=O)N(CCCN2CCC(Cc3ccccc3)CC2)c2cccnc2)CC1.Cl,,CCOC(C)=O,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20050124613A1,CC(C)(C)OC(=O)N1CCN(c2cccc3c2OC(C)(C)CN3S(=O)(=O)c2ccccc2F)CC1>>CC1(C)CN(S(=O)(=O)c2ccccc2F)c2cccc(N3CCNCC3)c2O1,,CCO,,Cl,,test
US04806549,CCOC(=O)C=CNc1ccccc1OC.O=C(Cl)C1CCCCC1>>CCOC(=O)C(=CNc1ccccc1OC)C(=O)C1CCCCC1,,C1CCOC1,,[H-].[Na+],,test
US20090088439A1,CCCn1c(N)c(N)c(=O)n(Cc2ccc(Cl)cc2)c1=O.O=C1CCCC1Cl>>CCCn1c(=O)n(Cc2ccc(Cl)cc2)c(=O)c2nc3c(nc21)CCC3,,CC(=O)O,CO,,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(CC(=O)OC(C)(C)C)c2ncnn12>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(CC(=O)O)c2ncnn12,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US20040186151A1,C/C=C\CBr.CC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2ccc(O)cc2)c2nc(-c3ccc(Cl)cc3Cl)c[nH]2)CC1>>C/C=C\Cn1cc(-c2ccc(Cl)cc2Cl)nc1[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CC[C@@H](CC)CC1,,CCOCC,,,,test
US20070232583A1,NCCc1ccccc1.O=S(=O)(Cl)c1cccc(-c2cc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)(F)F)n3)ccn2)c1>>O=S(=O)(NCCc1ccccc1)c1cccc(-c2cc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)(F)F)n3)ccn2)c1,,C1CCOC1,,CCN(CC)CC,Cl,test
US20080300242A1,CCOc1cc(N2CCC(CCS(C)(=O)=O)CC2)c(C)cc1N.COc1ccc(-c2nc3ccccn3c2-c2ccnc(Cl)n2)cc1C(=O)Nc1c(F)cccc1F>>CCOc1cc(N2CCC(CCS(C)(=O)=O)CC2)c(C)cc1Nc1nccc(-c2c(-c3ccc(OC)c(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1,,OCC(F)(F)F,,Cl,,test
US06046210,CCOC(=O)N1C(=O)c2ccccc2C1=O.CCOC(CCCN)OCC>>CCOC(CCCN1C(=O)c2ccccc2C1=O)OCC,,C1CCOC1,,,,test
US20020119983A1,O=CCCc1cc(-c2nccs2)no1.c1ccc(CN2CCNCC2)cc1>>c1ccc(CN2CCN(CCCc3cc(-c4nccs4)no3)CC2)cc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20030088096A1,CC1CCN(c2nc(S(C)(=O)=O)nc(Cl)c2-c2ccccc2)CC1.CNC#N>>CC1CCN(c2nc(N(C)C#N)nc(Cl)c2-c2ccccc2)CC1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US08604015B2,Fc1cccc(C(OC(=S)N[C@H]2CN3CCC2CC3)c2cccc(F)c2)c1.O=C(CCl)c1cccs1>>O=C(C[N+]12CCC(CC1)[C@@H](NC(=S)OC(c1cccc(F)c1)c1cccc(F)c1)C2)c1cccs1.[Cl-],,CCOC(C)=O,,,,test
US04125732,COC(=O)C(Br)c1ccc(OCC(C)Oc2ccc(C(C)(C)C)cc2)cc1.Oc1cccc(C(F)(F)F)c1>>COC(=O)C(Oc1cccc(C(F)(F)F)c1)c1ccc(OCC(C)Oc2ccc(C(C)(C)C)cc2)cc1,,C1CCOC1,,,,test
US20060252751A1,OC1(c2cncnc2)CCC2(CC1)OCCO2>>O=C1CCC(O)(c2cncnc2)CC1,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US05753679,O=C(OC1CCN(Cc2ccccc2[N+](=O)[O-])CC1)c1ccccc1>>Nc1ccccc1CN1CCC(OC(=O)c2ccccc2)CC1,[Ni],CCO,,,,test
US20100331378A1,CC1(c2cc(CO)cs2)OCCO1.CS(=O)(=O)Cl>>CC1(c2cc(CCl)cs2)OCCO1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,N#N,test
US20130005981A1,CC(C)(C)O.Nc1cccc(CCl)n1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)Nc1cccc(CCl)n1,,CC(C)(C)O,O,Cc1ccccc1,[Na+].[OH-],test
US20110086854A1,CC(C)(C)CC1N(C(=O)Cl)CC(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.CC1(C)OC[C@H](CCN)O1>>CC(C)(C)CC1N(C(=O)NCC[C@H](O)CO)CC(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F,,C1CCOC1,,CCN(CC)CC,Cl,test
US20130005983A1,COc1ccc2c(=O)[nH]sc2c1.O=S(Cl)Cl>>COc1ccc2c(Cl)nsc2c1,,Clc1ccccc1,,CN(C)C=O,,test
US05679696,COC(=O)c1ccc(OCc2ccccc2)c(OC2CCCC2)c1>>COC(=O)c1ccc(O)c(OC2CCCC2)c1,[Pd],CO,,O=C[O-].[NH4+],,test
US20100197651A1,COc1cn(-c2cccc(Br)c2F)nc(-c2ccnn2-c2ccccc2)c1=O.OB(O)c1cccnc1>>COc1cn(-c2cccc(-c3cccnc3)c2F)nc(-c2ccnn2-c2ccccc2)c1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20160002264A1,CC1(C)CCC([C@H]2C[C@H]3CSC(NC(=O)c4ccccc4)=N[C@@]3(c3ccc(F)cc3F)CO2)O1>>CC1(C)CCC([C@H]2C[C@H]3CSC(N)=N[C@@]3(c3ccc(F)cc3F)CO2)O1,,CCO,,CN,,test
US04929613,CCOC=C(C(=O)OCC)C(=O)c1cc(F)c(C2CCN(C)CC2)cc1F.NC1CC1>>CCOC(=O)C(=CNC1CC1)C(=O)c1cc(F)c(C2CCN(C)CC2)cc1F,,CCOCC,,,,test
US20110034507A1,CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CCl.CCOC(=O)c1cc(-c2ccc3cc(O)ccc3c2)ccc1Cl>>CCOC(=O)c1cc(-c2ccc3cc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)ccc3c2)ccc1Cl,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20060106075A1,NCc1ccccc1.O=C(O)Cc1ccc(Br)cc1>>O=C(Cc1ccc(Br)cc1)NCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20160159809A1,CS(=O)(=O)Cl.c1ccc(C(CNc2nc(-c3ccc4[nH]ccc4c3)nc3ccccc23)c2ccccc2)cc1>>CS(=O)(=O)n1ccc2cc(-c3nc(NCC(c4ccccc4)c4ccccc4)c4ccccc4n3)ccc21,,CS(C)=O,,,,test
US20120115856A1,Cc1nc2cc(-c3cc4ccccc4n3C(=O)OC(C)(C)C)ccc2n1C1CCOCC1>>Cc1nc2cc(-c3cc4ccccc4[nH]3)ccc2n1C1CCOCC1,,Cl,,,,test
US20030225068A1,CC(C)(C(=O)O)C(=O)O.CSc1ccc(N)cc1>>CSc1ccc(NC(=O)C(C)(C)C(=O)O)cc1,,C1CCOC1,,O=S(Cl)Cl,,test
US20110172429A1,Nc1nnc(-c2ccco2)o1.O=C(Cl)c1cc(-c2ccccc2)nc2ccccc12>>O=C(Nc1nnc(-c2ccco2)o1)c1cc(-c2ccccc2)nc2ccccc12,,CO,,c1ccncc1,,test
US04173650,COc1ccc(C(=O)CBr)cc1.[C-]#N>>COc1ccc(C(=O)CC#N)cc1,,O,,CCO,,test
US20030186989A1,CCOC(=O)c1cccnc1Oc1ccc2nonc2c1>>O=C(O)c1cccnc1Oc1ccc2nonc2c1,,C1CCOC1,,[Li+].[OH-],,test
US20080132519A1,CCNc1ccc(C#N)cc1[N+](=O)[O-]>>CCNc1ccc(C#N)cc1N,[Pd],CCOC(C)=O,,,,test
US20080146625A1,CC(C)O/N=C(/C(=O)Nc1ccnn1C(=O)OC(C)(C)C)c1ccc(S(C)(=O)=O)c(Cl)c1>>CC(C)O/N=C(/C(=O)Nc1cc[nH]n1)c1ccc(S(C)(=O)=O)c(Cl)c1,,C1COCCO1,,Cl,,test
US05364866,CC(=O)Cl.NCCN1CCC(c2noc3cc(F)ccc23)CC1.O=C(O)/C=C/C(=O)O>>NC(=O)CCCN1CCC(c2noc3cc(F)ccc23)CC1.O=C(O)/C=C/C(=O)O,,CCO,ClCCl,CCN(CC)CC,,test
US20100286116A1,COC(=O)c1cnc(CCc2c(-c3ccccn3)noc2C)s1>>Cc1onc(-c2ccccn2)c1CCc1ncc(C(=O)O)s1,,C1CCOC1,O,[Li+].[OH-],,test
US20090264445A1,CCOC(=O)C=C(C)Oc1ccc(OC)cc1.O=C1CCC(=O)N1Br>>CCOC(=O)C=C(CBr)Oc1ccc(OC)cc1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20110118245A1,COC(=O)c1cc(O)c(OC)cc1[N+](=O)[O-].ClCc1ccccc1>>COC(=O)c1cc(OCc2ccccc2)c(OC)cc1[N+](=O)[O-],,CN(C)C=O,,[I-].[K+],,test
US20050272750A1,CCN(CC)CC.CN1CCCC1=O.C[C@H](O)[C@@H](N)CO.Nc1nc2nc(SCc3cccc(F)c3F)nc(Cl)c2s1>>CCCC(C)C.C[C@H](O)[C@H](CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(N)sc12,,CCOC(C)=O,CN1CCCC1=O,O,,test
US20060135522A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cccc2c1Sc1cc(Br)ccc1C2C1CCNCC1>>COc1cccc2c1Sc1cc(Br)ccc1C2C1CCN(C(=O)OC(C)(C)C)CC1,,C1COCCO1,,[Na+].[OH-],,test
US05232940,C[Si](C)(C)Cl.N#Cc1cn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)nc1C(F)(F)F>>C[Si](C)(C)c1c(C#N)c(C(F)(F)F)nn1-c1c(Cl)cc(C(F)(F)F)cc1Cl,,C1CCOC1,ClCCl,[Li]CCCC,,test
US20150376212A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Nc1ncc(-c2ncc(Cl)cc2F)cn1>>CC1(C)OB(c2cnc(-c3cnc(N)nc3)c(F)c2)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20030008882A1,COc1ccc(-c2ccc(-c3ccc(CCC#N)cc3CC(C)C)cc2Cc2cccc3ccccc23)cc1CC(C)C>>CC(C)Cc1cc(-c2ccc(-c3ccc(CCC#N)cc3CC(C)C)cc2Cc2cccc3ccccc23)ccc1O,,ClCCl,,BrB(Br)Br,O,test
US20090105211A1,Cc1cccc(C)c1N.O=C(O)c1ccc(Nc2nc(C3CCCCC3)c3ccccc3n2)cc1>>Cc1cccc(C)c1NC(=O)c1ccc(Nc2nc(C3CCCCC3)c3ccccc3n2)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040248951A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)COc1c(C)cc(N)cc1C>>CCOC(=O)COc1c(C)cc(NC(=O)OC(C)(C)C)cc1C,,C1CCOC1,,,,test
US20120053174A1,CSc1nc(C(F)(F)c2ccc(F)cn2)nc2cc(C#N)ccc12.O=S(=O)(O)O>>CSc1nc(C(F)(F)c2ccc(F)cn2)nc2cc(C(N)=O)ccc12,,O,,O=C([O-])O.[Na+],,test
US20090197866A1,CC(C)(C)OC(=O)N1CCN(c2cc3[nH]c(-c4nn(C5CCCCO5)cc4NC(=O)N4CCCCC4)nc3cc2F)CC1>>O=C(Nc1c[nH]nc1-c1nc2cc(F)c(N3CCNCC3)cc2[nH]1)N1CCCCC1,,O=C(O)C(F)(F)F,,O,,test
US20160090309A1,C1=C(N2CCCC2)CCC1.CCO>>C[N+]1(C2CCCC2)CCCC1.[OH-],[Pd],,,[H][H],,test
US20050026976A1,CC(C)(C)OC(=O)CBr.O=C1NCc2c(Br)cc(O)cc21>>CC(C)(C)OC(=O)COc1cc(Br)c2c(c1)C(=O)NC2,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090275753A1,CC1=C2OC(C)(C)CC2C(C=O)C([N+](=O)[O-])=C1C.CCOP(=O)(Cc1ccccc1)OCC>>CC1=C2OC(C)(C)CC2C(C=Cc2ccccc2)C([N+](=O)[O-])=C1C,,C1CCOC1,,[H-].[Na+],,test
US20080262021A1,CN1CCNCC1.Fc1ccc(-n2cnc3cnc4ccc(Br)cc4c32)cc1>>CN1CCN(c2ccc(-n3cnc4cnc5ccc(Br)cc5c43)cc2)CC1,,CS(C)=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US06573270B1,BrCCOc1ccccc1.Cc1ccc(-c2c(O)nn(C)c2N)cc1>>Cc1ccc(-c2c(OCCOc3ccccc3)nn(C)c2N)cc1,,CN(C)C=O,O,[H-].[Na+],,test
US20070203130A1,Nc1nccs1.O=CNc1cccc2c(S(=O)(=O)Cl)cccc12>>O=CNc1cccc2c(S(=O)(=O)Nc3nccs3)cccc12,,c1ccncc1,,,,test
US20150376130A1,CC(C)CN.COC(=O)c1cc(F)cnc1Cl>>CC(C)CNc1ncc(F)cc1C(=O)O,,C1CCOC1,,CCO,[Na+].[OH-],test
US20100210696A1,OCc1cc(Nc2ccccc2)n(-c2ccccc2)n1>>O=Cc1cc(Nc2ccccc2)n(-c2ccccc2)n1,,CS(C)=O,,CCN(CC)CC,O,test
US20110147681A1,CCC(=O)Cl.COc1ccc(C2(c3ccc(OC)cc3)C=Cc3c(C(=O)OCCO)c(-c4ccccc4)c4ccccc4c3O2)cc1>>CCC(=O)OCCOC(=O)c1c2c(c3ccccc3c1-c1ccccc1)OC(c1ccc(OC)cc1)(c1ccc(OC)cc1)C=C2,,CCN(CC)CC,ClCCl,,,test
US20120232074A1,COc1cc2c(NCc3sc(C)nc3C)c(N)cnc2cc1-c1c(C)noc1C.O=C(O)C1CCOCC1>>COc1cc2c(NCc3sc(C)nc3C)c(NC(=O)C3CCOCC3)cnc2cc1-c1c(C)noc1C,,ClCCl,O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06169091A,Cc1csc2ncnc(Cl)c12.Nc1ccc(OCc2ccccc2F)c(Cl)c1>>Cc1csc2ncnc(Nc3ccc(OCc4ccccc4F)c(Cl)c3)c12.Cl,,CC(C)O,,,,test
US20110015178A1,FC1(F)CCCNCC1.O=C(O)c1csc(-c2ccccc2)c1>>O=C(c1csc(-c2ccccc2)c1)N1CCCC(F)(F)CC1,,CC#N,,Cl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110301200A1,CCOC(=O)C(C)ON=Cc1cc(Br)c(Oc2ccc(OC)c(S(=O)(=O)N3CCCCC3)c2)c(Br)c1>>CC(ON=Cc1cc(Br)c(Oc2ccc(O)c(S(=O)(=O)N3CCCCC3)c2)c(Br)c1)C(=O)O,,ClCCl,ClCCl,BrB(Br)Br,,test
US20040143007A1,ClC1(Cl)CC1CBr.N#Cc1ccc(CC(C#N)C#N)cc1>>N#Cc1ccc(CC(C#N)(C#N)CC2CC2(Cl)Cl)cc1,,CN(C)C=O,,[H-].[Na+],,test
US05324747,CCCCCCCCCCNC(=O)c1ccc([N+](=O)[O-])cc1>>CCCCCCCCCCNC(=O)c1ccc(N)cc1,[Pd],C1CCOC1,,,,test
US04857227,O=C(O)c1ccc(-c2ccc(OCc3ccccc3)cc2)cc1.O=S(Cl)Cl>>O=C(Cl)c1ccc(-c2ccc(OCc3ccccc3)cc2)cc1,CN(C)C=O,,,,,test
US20100010053A1,CCOC(=O)CCCc1c[nH]c2c(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)cccc12.COC(=O)OC>>CCOC(=O)CCCc1cn(C)c2c(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)cccc12,,CN(C)C=O,,C1CN2CCN1CC2,,test
US05514711,COc1cc(C=C(C#N)C(=O)Nc2ccccc2)cc(Cl)c1O>>N#CC(=Cc1cc(O)c(O)c(Cl)c1)C(=O)Nc1ccccc1,,ClCCl,,BrB(Br)Br,O,test
US20140030221A1,C[C@@H](N[S@](=O)C(C)(C)C)c1ccc2cnc(Cl)cc2c1.Cl>>C[C@@H](N)c1ccc2cnc(Cl)cc2c1.Cl,,CO,,C1COCCO1,,test
US06235900B1,COC(=O)c1ccc(C#N)cc1Cl.OO>>COC(=O)c1ccc(C(N)=O)cc1Cl,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050159409A1,CSc1nc(Cl)c(C(=O)N(CCCNC(=O)OC(C)(C)C)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c(Cl)n1.Cl>>CSc1nc(Cl)c(C(=O)N(CCCN)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c(Cl)n1.Cl,,CCOC(C)=O,Cl,,,test
US20150166565A1,CCOC(=O)c1c(N)sc2c1CCCC2.COCC#N>>COCc1nc(O)c2c3c(sc2n1)CCCC3,,C1COCCO1,Cl,,,test
US20080070928A1,O=C(Nc1cc(F)c(OCc2ccccc2)cc1[N+](=O)[O-])c1cnccn1.Oc1ccccc1F>>O=C(Nc1cc(Oc2ccccc2F)c(OCc2ccccc2)cc1[N+](=O)[O-])c1cnccn1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20050107364A1,CC(C)(C)CC[C@@]1(C)C(=O)C(C2=NS(=O)(=O)c3cc(NC(=O)OC(C)(C)C)ccc3N2)=C(O)c2ccccc21.Cl>>CC(C)(C)CC[C@@]1(C)C(=O)C(C2=NS(=O)(=O)c3cc(N)ccc3N2)=C(O)c2ccccc21.Cl,,C1COCCO1,,,,test
US20030232818A1,CCOC(=O)c1cn(CCC#N)c2nc(N3CC(N)C(O)C3)c(F)cc2c1=O>>N[C@@H]1CN(c2nc3[nH]cc(C(=O)O)c(=O)c3cc2F)C[C@@H]1O,,CCO,,Cl,[Na+].[OH-],test
US20100004238A1,O=C1CCc2ccc(O)cc21.O=[N+]([O-])c1ccc(F)c(Cl)c1>>O=C1CCc2ccc(Oc3ccc([N+](=O)[O-])cc3Cl)cc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20090239845A1,COC(=O)c1ccc(N)nc1.Cc1cc(C(=O)On2nnc3ccccc32)nn1Cc1cc(Cl)ccc1OCC(C)C>>COC(=O)c1ccc(NC(=O)c2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)nc1,CN(C)c1ccncc1,ClCCl,,,,test
US20040102645A1,CS(=O)(=O)Cl.O=C(O)C[C@H](O)C(=O)O>>CS(=O)(=O)O[C@@H](CC(=O)O)C(=O)O,,C1CCOC1,,,,test
US20100160255A1,CC1(C)CC2(CCCN(C3CCN(C(=O)c4c(N)sc5ccccc45)CC3)C2)C(=O)O1.CN.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)CC(C)(C)OC3=O)CC1,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20120142705A1,COC(=O)C(CC(C)C)N1C(=O)C(=O)c2cc(C)ccc21>>Cc1ccc2c(c1)C(=O)C(=O)N2C(CC(C)C)C(=O)O,,C1CCOC1,O,[Li+].[OH-],,test
US20070259886A1,COC(=O)c1cccc(OC)c1C(=O)OC>>COc1cccc(C(=O)O)c1C(=O)O,,O,,CO,[K+].[OH-],test
US20030100770A1,CCO.Cc1ccc(S(=O)(=O)O[C@@H]2C[C@H](C(=O)OCc3ccccc3)N(C(=O)OC(C)(C)C)C2)cc1.c1ccc([Se][Se]c2ccccc2)cc1>>CCOC(=O)[C@H]1C[C@H]([Se]c2ccccc2)CN1C(=O)OC(C)(C)C,,CCO,,[BH4-].[Na+],,test
US20080070973A1,COc1cc(C(F)(F)F)cc(C(F)(F)F)c1C(=O)NC(c1ccccc1)C(C)(C)N1CCCC1>>COc1cc(C(F)(F)F)cc(C(F)(F)F)c1C(=O)NC(c1ccccc1)C(C)(C)N1CCCC1,,CCOC(C)=O,,Cl,O=C([O-])O.[Na+],test
US20040072818A1,C[C@@H]1CC[C@H](N)CC1.Clc1ccc2c(N3CCNCC3)ccnc2c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>C[C@@H]1CC[C@H](NC(=O)N2CCN(c3ccnc4cc(Cl)ccc34)CC2)CC1,,CO,ClCCl,CCN(C(C)C)C(C)C,,test
US20120029190A1,N#Cc1nccnc1Cl.c1ccc(-c2nc3c(o2)CCN(c2cnccn2)C3)cc1>>N#Cc1nccnc1N1CCc2oc(-c3ccccc3)nc2C1,,CCOC(C)=O,,,,test
US20090054407A1,CC(C)(C)OC(=O)n1c(-c2ccc(Cl)c3c2C(=O)NC3)cc2ccccc21>>O=C1NCc2c(Cl)ccc(-c3cc4ccccc4[nH]3)c21,,CO,,Cl,,test
US20070088040A1,CCOC(=O)c1cn(Cc2ccc(OC)cc2OC)c2nc(Cl)c(F)cc2c1=O.OC[C@H]1CCCN1>>CCOC(=O)c1cn(Cc2ccc(OC)cc2OC)c2nc(N3CCC[C@@H]3CO)ccc2c1=O,,CC#N,,CCN(C(C)C)C(C)C,O,test
US04668397,COC(=O)[C@@H]1CCCN1C(=O)CN(C)C(=O)[C@@](N)(CCCC(N)C(=O)OCc1ccccc1)C(=O)OC(C)(C)C.Cl>>COC(=O)[C@@H]1CCCN1C(=O)CN(C)C(=O)[C@@H](N)CCCC(N)C(=O)OCc1ccccc1.Cl,,CCOC(C)=O,,,,test
US20020010183A1,CN(C)C=O.c1cnc(N2CCc3c([nH]c4ccccc34)C2c2ccc3c(c2)OCO3)nc1>>O=c1c2c([nH]c3ccccc13)C(c1ccc3c(c1)OCO3)N(c1ncccn1)C2,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20140296252A1,Cc1nc(NN=C(c2ccccc2)c2ccccc2)ccc1Oc1ccnc(Cl)c1>>Cc1nc(NN)ccc1Oc1ccnc(Cl)c1,,Cc1ccccc1,,Cl,,test
US07176310B1,Cc1nc(S(=O)CC(N)=O)ncc1C(=O)Nc1ccc(F)cc1.O=C(OO)c1cccc(Cl)c1>>Cc1nc(S(=O)(=O)CC(N)=O)ncc1C(=O)Nc1ccc(F)cc1,,CCOC(C)=O,ClCCl,CN(C)C=O,,test
US20070093496A1,COC(=O)CBr.NCc1ccc(F)cc1>>COC(=O)CNCc1ccc(F)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20110172230A1,CC(C)(C)OC(=O)N1CCNCC1.ClCCl.O=Cc1ccc(-c2ccccc2)s1>>Cl.Cl.c1ccc(-c2ccc(CN3CCNCC3)s2)cc1,,O,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US06197729B1,COC(=O)C(C(=O)OC)C1CCC(=O)CC1.NCc1ccccc1>>COC(=O)C(C(=O)OC)[C@@H]1CC[C@H](NCc2ccccc2)CC1,[Pd],CO,,[H][H],,test
US20140275065A1,COC(=O)c1c(OC)cccc1-c1ncccn1>>COc1cccc(-c2ncccn2)c1C(=O)O,,C1CCOC1,,[Na+].[OH-],,test
US20080039468A1,CC1Cc2nnc(-c3cccc(C(F)(F)F)c3)cc2C(O)C1.O=C(Cl)Oc1ccccc1>>CC1Cc2nnc(-c3cccc(C(F)(F)F)c3)cc2C(OC(=O)Oc2ccccc2)C1,,Cc1ccccc1,,O,c1ccncc1,test
US20150011548A1,CCOC(=O)CBr.CN1CCNCC1>>CCOC(=O)CN1CCN(C)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090069340A1,Cc1cc(=O)n(C2CCCCC2)n1C.O=C1CCC(=O)N1Br>>Cc1c(Br)c(=O)n(C2CCCCC2)n1C,,ClC(Cl)Cl,,,,test
US20120040957A1,COc1cnc2ccc(OC)nc2c1.O=P(Cl)(Cl)Cl>>COc1cnc2ccc(Cl)nc2c1,,CN(C)C=O,,,,test
US06090804,Nc1nnc(-c2ccc(CN3CCCCCC3)s2)o1.O=C=NCc1ccccc1>>O=C(NCc1ccccc1)Nc1nnc(-c2ccc(CN3CCCCCC3)s2)o1,,c1ccncc1,,,,test
US05254685,COC(=O)c1cn2c3c(c(F)c(F)cc3c1=O)CC(C)N2C>>CC1Cc2c(F)c(F)cc3c(=O)c(C(=O)O)cn(c23)N1C,,O,,CC(=O)O,Cl,test
US04132710,O[C@@H]1CN(Cc2ccccc2)CC[C@H]1c1ccccc1>>O[C@@H]1CNCC[C@H]1c1ccccc1,[Pd],CCO,,Cl,,test
US03941802,NN.Nc1ccccc1C(=O)c1ccccc1Cl>>NN=C(c1ccccc1N)c1ccccc1Cl,,OCCOCCO,,O,,test
US06121477,CCOC(=O)CC(=O)OCC.ClCc1ccccc1>>CCOC(=O)C(Cc1ccccc1)C(=O)OCC,,CCO,,C[O-].[Na+],,test
US20010047115A1,FC(F)(Cl)C(F)(Cl)OC(Cl)(Cl)C(F)(F)C(F)(Cl)C(F)(F)Cl>>FC(F)=C(F)OC(Cl)(Cl)C(F)(F)C(F)=C(F)F,[Zn],CN(C)C=O,,,,test
US20020169172A1,CO.N#Cc1nc(-c2cc(Cl)cc(Cl)c2Cl)c(N)nc1N>>Nc1nc(N)c(-c2cc(Cl)cc(Cl)c2Cl)nc1C=O,,Cc1ccccc1,,CC(C)C[Al+]CC(C)C.[H-],,test
US04025537,CCCC=C(C(C)=O)C(=O)OCC>>CCOC(=O)c1cc(CC)oc1C,,ClC(Cl)(Cl)Cl,,O=C1CCC(=O)N1Br,,test
US06060608,C=CCBr.CC(C)(C)OC(=O)Nc1cc(OCc2ccccc2)c2ccc(C#N)cc2c1I>>C=CCN(C(=O)OC(C)(C)C)c1cc(OCc2ccccc2)c2ccc(C#N)cc2c1I,,CN(C)C=O,,[H-].[Na+],,test
US20160009718A1,CCOC(=O)c1c(C)c(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)n2ncccc12>>CCOC(=O)c1c(C)c(C(=O)N2CCNCC2)n2ncccc12,,CO,Cl,,,test
US20110178063A1,C[Sn](C)(C)c1cc(N)c2c(F)nn(S(=O)(=O)c3ccccc3)c2c1.O=[N+]([O-])c1ccc(S(=O)(=O)n2ccc3c(Br)cc(F)cc32)cc1>>Nc1cc(-c2cc(F)cc3c2ccn3S(=O)(=O)c2ccc([N+](=O)[O-])cc2)cc2c1c(F)nn2S(=O)(=O)c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US03952007,CN(C)C=Cc1ncc([N+](=O)[O-])n1CCO.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCCn2c([N+](=O)[O-])cnc2C=CN(C)C)cc1,,c1ccncc1,,,,test
US20090082358A1,FC(F)(F)c1ccc(C2=NCCc3ccncc32)cc1>>FC(F)(F)c1ccc(C2NCCc3ccncc32)cc1,,CO,,[BH4-].[Na+],,test
US20070149810A1,CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc2cc(C(=O)O)ccc2s1.CNC>>CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc2cc(C(=O)N(C)C)ccc2s1,,CCN(CC)CC,ClCCl,ClCCCl,On1nnc2ccccc21,test
US20050070441A1,CCc1c(Oc2ncc(C(F)(F)F)cc2Cl)n[nH]c1C.CN=C=O>>CCc1c(Oc2ncc(C(F)(F)F)cc2Cl)nn(C(=O)NC)c1C,,CCOC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20060258691A1,CC(C)NC(=O)c1nn(C(C)(C)C)c2nc(N)ccc12.Cc1ccc(C(=O)Cl)cc1>>Cc1ccc(C(=O)Nc2ccc3c(C(=O)NC(C)C)nn(C(C)(C)C)c3n2)cc1,,c1ccncc1,,,,test
US05354866,CC(C)[C@H](N)C(=O)OCc1ccccc1.CCN(CC)CC.O=S(=O)(Cl)c1ccncc1>>CCS(=O)(=O)N(c1ccncc1)[C@H](C(=O)OCc1ccccc1)C(C)C,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090209523A1,CCS(=O)(=O)Cl.O=C(c1cc(Cc2c[nH]c(=O)c3cc(Cl)c(Cl)n23)ccc1F)N1CCNCC1>>CCS(=O)(=O)N1CCN(C(=O)c2cc(Cc3c[nH]c(=O)c4cc(Cl)c(Cl)n34)ccc2F)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20030187026A1,Clc1ccc2c(Cl)ncnc2n1.Nc1ccccc1>>Clc1ccc2c(Nc3ccccc3)ncnc2n1,,C1CCOC1,CC(C)O,,,test
US20030158177A1,CC(=O)N1CCCCc2ccccc21.O=C(Cl)CCCl>>CC(=O)N1CCCCc2ccc(C(=O)CCCl)cc21,,CC(Cl)Cl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20140045855A1,C=CCCCBr.Nc1cccnc1Br>>C=CCCCNc1cccnc1Br,,O,,CN(C)C=O,[H-].[Na+],test
US20060079567A1,CCOC(=O)C1=C(c2ccsc2)CCN(Cc2ccccc2)C1>>CCOC(=O)C1CN(Cc2ccccc2)CCC1c1ccsc1,[Pd],CCO,,,,test
US20070155839A1,CC(C)(C)OC(=O)/C=C/c1ccc(C(=C2CCCCC2)c2ccc(O)cc2)cc1F>>O=C(O)/C=C/c1ccc(C(=C2CCCCC2)c2ccc(O)cc2)cc1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100291026A1,CCOC(=O)CC#N.C[C@@H]1CCNC[C@@H]1N(C)c1ncnc2[nH]ccc12>>C[C@@H]1CCN(C(=O)CC#N)C[C@@H]1N(C)c1ncnc2[nH]ccc12,,Cc1ccccc1,,CCN(CC)CC,,test
US20100113512A1,COC(=O)c1csc(Br)n1>>O=C(O)c1csc(Br)n1,,C1CCOC1,,[Li+].[OH-],,test
US06326369B1,CCOC(=O)C1(c2ccc(OCc3ccccc3)cc2)Cc2c(OC)c(OC)c(OC)c(OC)c2C1O>>CCOC(=O)C1(c2ccc(OCc3ccccc3)cc2)Cc2c(c(OC)c(OC)c(OC)c2OC)C1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US05491152,C=C(C)C(=C)C.CCOC(=O)C(=O)C(=O)OCC>>CCOC(=O)C1(C(=O)OCC)CC(C)=C(C)CO1,,CC#N,,,,test
US05424435,Sc1ccccc1.[O-][n+]1c(Cl)cccc1Cl>>[O-][n+]1c(Cl)cccc1-c1cccs1,,CS(C)=O,,[Na+].[OH-],,test
US04837305,CC(=O)Nc1ccc(OCC(O)CN2C(=O)c3ccccc3C2=O)cc1.Cl>>CC(=O)Nc1ccc(OCC(O)CN)cc1.Cl,,CCO,,NN,O,test
US20050267093A1,C1COCCN1.COc1cc([N+](=O)[O-])ccc1OCCBr>>COc1cc([N+](=O)[O-])ccc1OCCN1CCOCC1,,CO,ClCCl,,,test
US20080045507A1,Br[Mg]C1CCCCC1.O=Cc1ccc(C(=O)N2CCN(C3CCC3)CC2)cc1>>O=C(c1ccc(C(O)C2CCCCC2)cc1)N1CCN(C2CCC2)CC1,,C1CCOC1,,,,test
US04197240,ClC(Cl)OC(Cl)Cl.O=C(O)C(c1ccc(O)cc1)S(=O)(=O)O>>O=C(O)C(c1ccc(O)c(CCl)c1)S(=O)(=O)O,,O=S(=O)(O)O,,,,test
US20130045286A1,Nc1c[nH]c2ncc(C(F)(F)F)c(Cl)c12.O=C(Cl)c1ccccn1>>O=C(Nc1c[nH]c2ncc(C(F)(F)F)c(Cl)c12)c1ccccn1,,c1ccncc1,,Cl,,test
US20090176778A1,CC(=O)Cl.Nc1cc(C(F)(F)F)c2nc(C(=O)N3CCC(c4ccc(F)cc4)C3)c(Cl)n2c1>>CC(=O)Nc1cc(C(F)(F)F)c2nc(C(=O)N3CCC(c4ccc(F)cc4)C3)c(Cl)n2c1,,CCOC(C)=O,CN(C)C=O,c1ccncc1,,test
US20150225396A1,CC(C)(C)OC(=O)CCC(=O)Nc1ncccc1C(N)=O>>CC(C)(C)OC(=O)CCc1nc2ncccc2c(=O)[nH]1,,C1CCOC1,O,[Li+].[OH-],,test
US20090137609A1,CCC(CC)(c1ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1ccc(-c2ccc([C@H](NC(=O)OC(C)(C)C)C(=O)OC)cc2)c(C)c1>>CCC(CC)(c1ccc(CCC(O)C(C)(C)C)c(C)c1)c1ccc(-c2ccc([C@H](N)C(=O)OC)cc2)c(C)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050245592A1,CC(=O)c1cc2c(c(C(C)(C)C)c1)OCCN2.N#CCBr>>CC(=O)c1cc2c(c(C(C)(C)C)c1)OCCN2CC#N,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20110105461A1,C1CCNC1.Cc1ccc(S(=O)(=O)OCC2COc3ccc(S(C)(=O)=O)cc3O2)cc1>>CS(=O)(=O)c1ccc2c(c1)OC(CN1CCCC1)CO2,,CC#N,,,,test
US20090264437A1,CC(C)(C)c1nc(C2CCC2)cc(N2CCN(CCCCl)CC2)n1.Oc1ccncn1>>CC(C)(C)c1nc(C2CCC2)cc(N2CCN(CCCOc3ccncn3)CC2)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090012138A1,CCNc1ccccc1.OCC1CO1>>CCN(CC(O)CO)c1ccccc1,,O,,CCO,,test
US20030162818A1,NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCc2ccccc2)c1.O=C(Cl)Oc1ccccc1>>O=C(NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCc2ccccc2)c1)Oc1ccccc1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20160052898A1,Cc1ccc([N+](=O)[O-])cc1N.O=C(Cl)CCl>>Cc1ccc([N+](=O)[O-])cc1NC(=O)CCl,,ClCCl,,c1ccncc1,,test
US20050070588A1,CCCCCBr.CN(C(=O)OC(C)(C)C)C1CCNC1>>CCCCCN1CCC(N(C)C(=O)OC(C)(C)C)C1,,CN(C)C=O,,[I-].[K+],,test
US20060019993A1,CC(=O)Oc1cc(Cl)ccc1OC[C@H](O)CN1C(=O)c2ccccc2C1=O.CS(=O)(=O)Cl>>CC(=O)Oc1cc(Cl)ccc1OC[C@@H](CN1C(=O)c2ccccc2C1=O)OS(C)(=O)=O,,CCOC(C)=O,,CCN(CC)CC,,test
US20100022513A1,CCOC(=O)c1sc(NC(=O)C(C)(C)NC(=O)c2ccc(F)cc2)nc1-c1ccc(F)cc1>>CC(C)(NC(=O)c1ccc(F)cc1)C(=O)Nc1nc(-c2ccc(F)cc2)c(C(=O)O)s1,,CCO,O,Cl,[K+].[OH-],test
US20090264434A1,CN(c1ccccc1)c1cn[nH]c(=O)c1.COC(=O)C(Br)CC1CCCC1>>COC(=O)C(CC1CCCC1)n1ncc(N(C)c2ccccc2)cc1=O,,C1CCOC1,,[H-].[Na+],,test
US05180723,CC(C)CC=O.CCCC[Mg]Cl>>CCCCC(O)CC(C)C,,C1CCOC1,,,,test
US06156758,COC(=O)c1nc(Cl)c(NC2CCNCC2)nc1N.COc1cc2nc(Cl)nc(N)c2cc1OC>>COC(=O)c1nc(Cl)c(NC2CCN(c3nc(N)c4cc(OC)c(OC)cc4n3)CC2)nc1N,,CC(C)CCO,,,,test
US20100197939A1,CC(C)(C)OC(=O)N1C[C@@H]([C@H](O)CO)CC1=O>>CC(C)(C)OC(=O)N1C[C@@H](C=O)CC1=O,,CO,O,,,test
US20100029938A1,CCOC(=O)C(=CN[C@@H](C)COC(C)=O)C(=O)c1cc(F)c(N2CCN(C)CC2)c(F)c1F>>CCOC(=O)c1cn([C@@H](C)COC(C)=O)c2c(F)c(N3CCN(C)CC3)c(F)cc2c1=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150336938A1,COc1cc2c(OC(=O)OC(C)(C)C)c3c(c(-c4ccc(C(C)=O)cc4)c2cc1OC)C(=O)OC3>>COc1cc2c(O)c3c(c(-c4ccc(C(C)=O)cc4)c2cc1OC)C(=O)OC3,,ClCCl,,C1CCNCC1,Cl,test
US20160272617A1,Cc1cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)O)cc1.Nc1ccc2[nH]c(-n3cccn3)nc2c1>>Cc1cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc3[nH]c(-n4cccn4)nc3c2)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06080754,CCc1c(-c2ccc(OC)cc2)c2cc(Br)c3cccc1n32.OB(O)c1ccc(OCc2ccccc2)cc1>>CCc1c(-c2ccc(OC)cc2)c2cc(-c3ccc(OCc4ccccc4)cc3)c3cccc1n32,,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US04816560,C[C@H](OC(C)(C)C)[C@@H](N)C(=O)NC(=O)OCc1ccccc1>>C[C@H](OC(C)(C)C)[C@@H](N)C(N)=O,[Pd],CO,,[H][H],,test
US20150344437A1,CC(=O)ON(C(=O)OC(C)(C)C)C1(C)C(=O)N(C)N=C1c1ccccc1>>CC(=O)ONC1(C)C(=O)N(C)N=C1c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05716936,CC(C)(C)CCNC(=O)C1CC(S(=O)(=O)N2CCOCC2)C(c2ccccc2F)N1C(=O)CNC(=O)Nc1cccc(C(=O)OCc2ccccc2)c1>>CC(C)(C)CCNC(=O)C1CC(S(=O)(=O)N2CCOCC2)C(c2ccccc2F)N1C(=O)CNC(=O)Nc1cccc(C(=O)O)c1,[Pd],CO,ClCCl,CCO,,test
US20120122843A1,CN.Cc1csc([C@@H](O)CCl)n1>>CNC[C@H](O)c1nc(C)cs1,,CCO,,,,test
US20130065248A1,COC(=O)c1ccc(C#C[Si](C)(C)C)cc1>>C#Cc1ccc(C(=O)O)cc1,,[K+],[OH-],CO,,test
US20070004911A1,CCN(CC)CC.O=P(O)(O)O>>CCN(CC)CC.O=P(O)(O)O,,O,,,,test
US20030236412A1,CCOC(=O)C(C=O)C(C)=O.NNc1ccccn1>>CCOC(=O)c1cn(-c2ccccn2)nc1C,,CCO,,c1ccncc1,,test
US20120115845A1,CS(=O)(=O)c1ccc2nc(NC(=O)Oc3ccc(F)cc3)sc2c1.NC(=O)c1cc(-n2cncn2)ccc1Cl>>CS(=O)(=O)c1ccc2nc(NC(=O)NC(=O)c3cc(-n4cncn4)ccc3Cl)sc2c1,,C1CCOC1,,Cl,CC(C)(C)[O-].[K+],test
US20080018238A1,ClCc1ccccc1.Oc1ccc(I)cc1>>Ic1ccc(OCc2ccccc2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20060252768A1,Cn1c(Cl)nc(-c2ccncc2)cc1=O.c1ccc(C[C@H]2CNCCN2)cc1>>Cn1c(N2CCN[C@@H](Cc3ccccc3)C2)nc(-c2ccncc2)cc1=O,,C1CCOC1,,CCN(CC)CC,,test
US20100048570A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)[C@@H](Nc1ccc(C#N)cc1)C(C)C>>CCOC(=O)[C@@H](Nc1ccc(CNC(=O)OC(C)(C)C)cc1)C(C)C,Cl[Ni]Cl,CCO,,[BH4-].[Na+],,test
US20140243302A1,CC(C)(C)OC(=O)NC12CCC(CCn3c(=O)ccc4ncc(OCc5ccccc5)cc43)(CC1)OC2>>CC(C)(C)OC(=O)NC12CCC(CCn3c(=O)ccc4ncc(O)cc43)(CC1)OC2,[Pd],CO,ClCCl,,,test
US20120226035A1,CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCNCC1.O=CCn1c(=O)ccc2ccncc21>>CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)ccc3ccncc32)CC1,,ClCCl,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20120157469A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1CC(=O)CCN1.CN(N)c1cccc(Br)c1>>CC1Cc2c(c3ccc(Br)cc3n2C)CN1C(=O)OC(C)(C)C,,CCO,Cl,CCN(CC)CC,,test
US20120149691A1,CC1CCN(Cc2ccccc2)CC1Nc1c(C#N)cnn2cccc12.OO>>CC1CCN(Cc2ccccc2)CC1Nc1c(C(N)=O)cnn2cccc12,,CCO,,[NH4+].[OH-],,test
US04738976,N#CC(=C1SCC(CCl)S1)n1ccnc1>>C=C1CSC(=C(C#N)n2ccnc2)S1,,C1CCOC1,,,,test
US20140179666A1,CC1(C)CNc2cc(C#N)ccc21.CCN(CC)CC.CN(C)C=O.ClCCl>>CC[C@@H](Cl)C(=O)N1CC(C)(C)c2ccc(C#N)cc21,,CCOC(C)=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US07060109B2,CCCCOC(=O)c1sc2ccc(O)cc2c1OC(=O)C(C)(C)C.CCOC(=O)CBr>>CCCCOC(=O)c1sc2ccc(OCC(=O)OCC)cc2c1OC(=O)C(C)(C)C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070108410A1,CCCCC[C@@H]1CC[C@@H](C(O)CCC(C)C(=O)OC(C)(C)C)CC1>>CCCCC[C@@H]1CC[C@@H](C2CCC(C)C(=O)O2)CC1,,ClCCl,O,O=C(O)C(F)(F)F,,test
US20120264735A1,CC(C)(C)OC(=O)N1CC[C@H](O)[C@H](F)C1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CC[C@H](OS(=O)(=O)C(F)(F)F)[C@H](F)C1,,ClCCl,,c1ccncc1,,test
US20100204231A1,Cc1cnc(N)s1.Clc1ncc(Cl)c(Cl)n1>>Cc1cnc(Nc2nc(Cl)ncc2Cl)s1,,CCO,,CCN(C(C)C)C(C)C,,test
US20110295004A1,CCOC(=O)CCBr.Oc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1>>CCOC(=O)COc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04737513,C#CCBr.O=Cc1cc[nH]c1>>C#CCn1ccc(C=O)c1,,C1CCOC1,,O,[H-].[Na+],test
US20090318708A1,CCCC(CC(=O)OCC)C[N+](=O)[O-]>>CCCC1CNC(=O)C1,,CO,,[H][H],,test
US20110053905A1,COC(=O)c1c[nH]c(-c2cc(Nc3cccc([N+](=O)[O-])c3)ccn2)c1>>COC(=O)c1c[nH]c(-c2cc(Nc3cccc(N)c3)ccn2)c1,,CCO,CCOC(C)=O,,,test
US04746746,COC1=C(C)C(=O)C2=C(C1=O)[C@@H](COC(N)=O)[C@@]1(OC)[C@H]3N[C@H]3CN21.OC1CCNC1>>COC12C(CO)C3=C(C(=O)C(C)=C(N4CCC(O)C4)C3=O)N1CC1NC12.NC(=O)O,,CO,,,,test
US20090143372A1,O=C1NC(=O)c2cc([N+](=O)[O-])ccc21>>Nc1ccc2c(c1)C(=O)NC2=O,[Pd],C1CCOC1,,,,test
US20100216814A1,CSc1ccc(C(C)=CBr)cc1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>CSc1ccc(/C(C)=C/n2c3c(c4cc(C)ccc42)CN(C)CC3)cc1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20160039846A1,CC1(C)OB(c2ccc(-c3nc4c(cc3Cl)nc(O[C@@H]3CO[C@@H]5[C@H](O)CO[C@H]35)n4COCC[Si](C)(C)C)cc2)OC1(C)C.CNS(C)(=O)=Nc1ccc(Cl)nc1>>CNS(C)(=O)=Nc1ccc(-c2ccc(-c3nc4c(cc3Cl)nc(O[C@@H]3CO[C@@H]5[C@H](O)CO[C@H]35)n4COCC[Si](C)(C)C)cc2)nc1,,COCCOC,,,,test
US20150353553A1,CI.C[C@H]1C[C@@H](O)CCN1C(=O)OC(C)(C)C>>CO[C@H]1CCN(C(=O)OC(C)(C)C)[C@@H](C)C1,,CN(C)C=O,,O,[H-].[Na+],test
US20160046618A1,C#C[C@H](C)O.Cc1nc(Cl)cnc1C(=O)OC(C)(C)C>>C#C[C@H](C)Oc1cnc(C(=O)OC(C)(C)C)c(C)n1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20100240671A1,COC(=O)C(NC(=O)OC(C)(C)C)P(=O)(OC)OC.O=Cc1ccc(Br)nc1>>COC(=O)C(=Cc1ccc(Br)nc1)NC(=O)OC(C)(C)C,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20020013374A1,C1CCNCC1.O=[N+]([O-])c1ccc(OCCCl)cc1>>O=[N+]([O-])c1ccc(OCCN2CCCCC2)cc1,,Cc1ccccc1,,,,test
US20070173488A1,Nc1ccc(C=O)c(Cl)c1.O=C=Nc1cccc(F)c1>>O=Cc1ccc(NC(=O)Nc2cccc(F)c2)cc1Cl,,CO,Cc1ccccc1,,,test
US20090149487A1,CC(C)(C)OC(=O)N[C@@H](CC1CCC(N)CC1)C(=O)O.Clc1ncc(-c2ccccc2)c(-c2ccccc2)n1>>CC(C)(C)OC(=O)N[C@@H](CC1CCC(Nc2ncc(-c3ccccc3)c(-c3ccccc3)n2)CC1)C(=O)O,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120083502A1,CC(O)c1nc2ccc(F)cn2c(=O)c1Br.O=C1NC(=O)c2ccccc21>>CC(c1nc2ccc(F)cn2c(=O)c1Br)N1C(=O)c2ccccc2C1=O,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140275084A1,CNc1ccccc1.COC(=O)c1ccnc(-c2cn(CCOS(C)(=O)=O)cn2)c1>>CN(CCn1cnc(-c2cc(C(=O)O)ccn2)c1)c1ccccc1,,Cc1ccccc1,,,,test
US20070155805A1,CNOC.Cc1c(C(=O)O)oc2cc(C(F)(F)F)ccc12>>CON(C)C(=O)c1oc2cc(C(F)(F)F)ccc2c1C,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20090186870A1,CC(C)N.O=C(NC(=O)c1cc(-n2cccc2)ccc1Cl)Nc1nc2ccc(S(=O)(=O)CCCI)cc2s1>>CC(C)NCCCS(=O)(=O)c1ccc2nc(NC(=O)NC(=O)c3cc(-n4cccc4)ccc3Cl)sc2c1,,C1CCOC1,,,,test
US20090137609A1,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.COC(=O)Cc1cc(Br)c(O)c(OC)c1>>COC(=O)Cc1cc(Br)c(O[Si](C)(C)C(C)(C)C)c(OC)c1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20080015191A1,CC(=O)Nc1ccc(O)cc1.Clc1cncc(Cl)n1>>CC(=O)Nc1ccc(Oc2cncc(Cl)n2)cc1,,CCOC(C)=O,,,,test
US20100190829A1,CC(C)(C)OC(=O)N1CCCC(N(CCCO)c2cccc(Cl)c2)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCCC(N(CCCOS(C)(=O)=O)c2cccc(Cl)c2)C1,,ClCCl,,CCN(CC)CC,O,test
US20110118245A1,CCc1cc(NC(=O)Oc2ccccc2)n(-c2ccccc2)n1.COc1cc2ncnc(Sc3cccc(N)c3)c2cc1OC>>CCc1cc(NC(=O)Nc2cccc(Sc3ncnc4cc(OC)c(OC)cc34)c2)n(-c2ccccc2)n1,,CCOC(C)=O,CS(C)=O,,,test
US20150376136A1,CN1C(=O)N(CC(=O)c2ccc([N+](=O)[O-])cc2)C(=O)C1(C)C1CCCCC1>>CN1C(=O)N(CC(=O)c2ccc(N)cc2)C(=O)C1(C)C1CCCCC1,[Pd],CO,,,,test
US20030069271A1,BrCC1CCC1.CCCc1c(O)c2cc(Cl)ccc2[nH]c1=O>>CCCc1c(OCC2CCC2)c2cc(Cl)ccc2[nH]c1=O,,CN(C)C=O,,[H-].[Na+],,test
US04036633,C=C1CC(=O)O1.Nc1cccc(OCc2ccccc2)c1>>CC(=O)CC(=O)Nc1cccc(OCc2ccccc2)c1,,c1ccccc1,,,,test
US20100240653A1,Brc1ccc(SCC2CCOCC2)cc1.O=S([O-])OO>>O=S(=O)(CC1CCOCC1)c1ccc(Br)cc1,,C1CCOC1,,O,,test
US20080214545A1,COC(=O)c1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(C)c3)cc2F)cc1>>Cc1cc(Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(CO)cc3)c(F)c2)ccn1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US04684655,BrCCCc1ccccc1.COC1=NC(c2cccc([N+](=O)[O-])c2)C(C(=O)OC(C)C)=C(C)N1>>COC1=NC(c2cccc([N+](=O)[O-])c2)=C(C(=O)OC(C)C)C(C)N1CCCc1ccccc1,,CCOCC,CN(C)C=O,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US03937707,C1CCNCC1.[O-][n+]1c2cccc(OCCCCl)c2[n+]([O-])c2cccc(O)c21>>[O-][n+]1c2cccc(OCCCN3CCCCC3)c2[n+]([O-])c2cccc(O)c21,,ClC(Cl)Cl,,,,test
US20040259923A1,CCOC(=O)Nc1nc(CCl)cs1.O>>CCOC(=O)Nc1nc(CO)cs1,,O,,C1COCCO1,,test
US20150361095A1,CON.C[C@H](NC(=O)OC(C)(C)C)c1nc2cccc(Cl)c2c(=O)n1-c1cccc(N)c1.O=C(n1ccnc1)n1ccnc1>>CONC(=O)Nc1cccc(-n2c([C@H](C)NC(=O)OC(C)(C)C)nc3cccc(Cl)c3c2=O)c1,,ClCCl,,Cl,,test
US05179085,CCOP(=O)(Cc1cccc(CC#N)c1)OCC>>CCOP(=O)(Cc1cccc(CCN)c1)OCC,[Ni],N,,,,test
US05952355,C=CCCC[Mg]Br.COc1cc(C=O)cc(OC)c1OC>>C=CCCCC(O)c1cc(OC)c(OC)c(OC)c1,,C1CCOC1,,Cl,,test
US04762839,CNC(=O)N1C(=O)C(=O)c2cc(Cl)c(Cl)cc21.NC(N)=S>>CN1C(=O)Nc2cc(Cl)c(Cl)cc2C1(O)C(=O)NC(N)=S,,C1CCOC1,,CCN(CC)CC,,test
US05149817,CCOC(=O)N1CCC(O)(c2ccc(Cl)c(Cl)c2)CC1>>OC1(c2ccc(Cl)c(Cl)c2)CCNCC1,,CCCCO,,[K+].[OH-],,test
US20120077781A1,NCCCN.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>NCCCNS(=O)(=O)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20100093694A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N)c(-c3cccc(C(=O)NC4(c5ccccc5)CC4)c3)cc12.COCC(=O)O>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(NC(=O)COC)c(-c3cccc(C(=O)NC4(c5ccccc5)CC4)c3)cc12,,C1CCOC1,CO,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US05143935,CCOC(=O)[C@@H]1C[C@@H](N=[N+]=[N-])CN1CC>>CCN1C[C@H](N)C[C@H]1CO,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20150239900A1,O=S(Cl)Cl.Oc1ncnc2cc(Cl)c(C(F)(F)F)cc12>>FC(F)(F)c1cc2c(Cl)ncnc2cc1Cl,CN(C)C=O,,,,,test
US06335324B1,O=S(=O)(Cl)Cl.O=S(=O)(O)c1ccc(-c2ccccc2)cc1>>O=S(=O)(Cl)c1ccc(-c2ccccc2)cc1,,ClCCl,,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060183921A1,CCOC(=O)c1c(-c2ccccc2)csc1N.O=C1OC(=O)c2ccccc21>>CCOC(=O)c1c(-c2ccccc2)csc1N1C(=O)c2ccccc2C1=O,,CC(=O)O,,,,test
US20010020034A1,Cc1cc(F)c(COc2nsc(NC(=O)Oc3ccccc3)c2C(N)=O)cc1F.NCCCCN1CCCC1>>Cc1cc(F)c(COc2nsc(NC(=O)NCCCCN3CCCC3)c2C(N)=O)cc1F,,C1CCOC1,,,,test
US20130225524A1,COC(=O)c1cc(N)ccc1Br.OB(O)c1ccccc1>>COC(=O)c1cc(N)ccc1-c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20130123500A1,Cn1nccc1-c1ccc(OS(=O)(=O)C(F)(F)F)cc1.OB(O)c1cccnc1>>Cn1nccc1-c1ccc(-c2cccnc2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20040138223A1,CC(C)c1ccc(N(Cc2cn[nH]c2)C(=O)C2CCCc3c(OCc4ccccc4)cccc32)cn1.O=C(Cl)C1CCCCC1>>CC(C)c1ccc(N(Cc2cnn(C(=O)C3CCCCC3)c2)C(=O)C2CCCc3c(OCc4ccccc4)cccc32)cn1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20070265225A1,CC1(C)C(=O)N[C@H](c2cc(F)cc(F)c2)C[C@@H]1O.CCOC(=O)CBr>>CCOC(=O)CN1C(=O)C(C)(C)[C@@H](O)C[C@H]1c1cc(F)cc(F)c1,,C1CCOC1,,[H-].[Na+],,test
US20130244958A1,CC(C)C(Cl)OC(=O)Cl.COCCOCCOCCO>>COCCOCCOCCOC(=O)OC(Cl)C(C)C,,ClCCl,,c1ccncc1,,test
US20130345181A1,Cn1nccc1B1OC(C)(C)C(C)(C)O1.Nc1ccc(Br)cc1Cl>>Cn1nccc1-c1ccc(N)c(Cl)c1,,CO,COCCOC,,,test
US20020183320A1,CC(=O)Cl.Nc1nc[nH]n1.O=Cc1c(F)cccc1Cl.[C-]#[N+]CCCC>>CCCCN(C(C)=O)c1c(-c2c(F)cccc2Cl)nc2nc[nH]n12,,[O-][Cl+3]([O-])([O-])O,,,,test
US20100137313A1,Cn1cc(S(=O)(=O)Cl)c(C(F)(F)F)n1.N>>Cn1cc(S(N)(=O)=O)c(C(F)(F)F)n1,,ClC(Cl)Cl,,C1CCOC1,,test
US20100035919A1,C1=C(c2c[nH]c3ncccc23)CCNC1.ClC(Cl)(Cl)c1nc(-c2cccnc2)no1>>C1=C(c2c[nH]c3ncccc23)CCN(c2nc(-c3cccnc3)no2)C1,,CO,CS(C)=O,,,test
US20060211682A1,C[C@H]1CNC(=O)[C@@H](C)N(C(=O)OCc2ccccc2)C1>>C[C@H]1CNC(=O)[C@@H](C)NC1,[Pd],CCO,,,,test
US20070265265A1,NC(N)=S.O=C(O)CBr.O=[N+]([O-])c1ccccc1>>Nc1nc(-c2ccc([N+](=O)[O-])cc2)cs1,,CCO,,CC(=O)[O-].[Na+],,test
US20060004052A1,CC(C)(C)OC(=O)N1CCCC[C@H]1C(=O)O.Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O>>CC(C)(C)OC(=O)N1CCCC[C@H]1C(=O)Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O,,CN(C)C=O,,CCN(CC)CC,,test
US20090298834A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CC(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1>>N[C@@H]1CC[C@@H](CC(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1,,CCOCC,ClCCl,Cl,,test
US20100063068A1,CC(C)(NC(=O)c1cccc(-c2cc3c(C(=O)O)c(-c4ccc(F)cc4)nn3cc2N(CCO)S(C)(=O)=O)c1)c1ccccc1.CCN(C(C)C)C(C)C.CN.CN(C)C=O.On1nnc2cccnc21>>CC(=O)[O-].CNC(=O)c1c(-c2ccc(F)cc2)nn2cc(N(CCO)S(C)(=O)=O)c(-c3cccc(C(=O)NC(C)(C)c4ccccc4)c3)cc12.[NH4+],,CN(C)C=O,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US20160068515A1,CC(C)c1noc(C2CCN(C(=O)OC(C)(C)C)CC2)n1>>CC(C)c1noc(C2CCNCC2)n1,,CCOC(C)=O,,Cl,,test
US20140087992A1,COC(=O)c1ccc(C(F)(F)F)cn1.COc1ccccc1NC(=O)OC(C)(C)C>>COc1cccc(C(=O)c2ccc(C(F)(F)F)cn2)c1NC(=O)OC(C)(C)C,,CCOCC,,[Li]C(C)(C)C,,test
US05563158,Cc1ccc(S(=O)(=O)O)cc1.OCCCc1ccncc1>>Cc1ccc(S(=O)(=O)OCCCC2CCNCC2)cc1,O=[Pt]=O,CCO,,,,test
US20050075370A1,COc1ccnc(CSc2nc3cc(OC(F)F)ccc3[nH]2)c1OC.[O-]Cl>>COc1ccnc(C[S+]([O-])c2nc3cc(OC(F)F)ccc3[nH]2)c1OC,,CCOC(C)=O,,[Na+].[OH-],,test
US05162360,CC(C)c1cccc(C(C)C)c1N=C=O.CCCCCCCCCCCCc1cc(N)on1>>CCCCCCCCCCCCc1cc(NC(=O)Nc2c(C(C)C)cccc2C(C)C)on1,,CC#N,,,,test
US04844835,O=C(Cl)OCc1ccccc1.O=C(O)c1ccc(O)cc1>>O=C(OCc1ccccc1)Oc1ccc(C(=O)O)cc1,,O,,[Na+].[OH-],,test
US20020019429A1,CCCC[Sn](Cl)(CCCC)CCCC.COC1CC(C=C(Br)Br)C(OC)O1>>CCCC[Sn](C#CC1CC(OC)OC1OC)(CCCC)CCCC,,CCOCC,,[Li]CCCC,[Cl-].[NH4+],test
US20160257653A1,COC(=O)c1ccc(C=CN(C)C)c([N+](=O)[O-])c1.O>>COC(=O)c1ccc(C=O)c([N+](=O)[O-])c1,,C1CCOC1,,,,test
US06645999B1,O=C1CC[C@H](C(=O)O)N1.c1ccncc1>>O=C1CC=C2COCN12,,c1ccncc1,,CC(=O)OC(C)=O,,test
US20080051435A1,Cc1ccsc1C(=CCCN1CCC[C@@H](C(=O)O)C1)c1sccc1C.O=C(O)C[C@@H](O)C(=O)O>>Cc1ccsc1C(=CCCN1CCC[C@@H](C(=O)O)C1)c1sccc1C.O=C([O-])C[C@@H](O)C(=O)[O-],,CC#N,CO,,,test
US20070054911A1,CCOC(=O)N1C2CCC1CC(N1CCC(Nc3ccc(F)cc3)CC1)C2.O=C(Cl)C1CCCCC1>>CCOC(=O)N1C2CCC1CC(N1CCC(N(C(=O)C3CCCCC3)c3ccc(F)cc3)CC1)C2,,ClCCl,,CCN(CC)CC,[Na+].[OH-],test
US20030229058A1,COc1ccc([N+](=O)[O-])cc1-c1cccc(C#N)c1.Cl>>COc1ccc([N+](=O)[O-])cc1-c1cccc(CN)c1.Cl,,C1CCOC1,,CO,,test
US20110319381A1,CCOC(=O)NC1CC2(CCN(c3ccc(CC(C)C)cn3)CC2)C1>>CC(C)Cc1ccc(N2CCC3(CC2)CC(N)C3)nc1,,CCO,O,[K+].[OH-],,test
US20090181928A1,OCc1c(OCc2ccccc2)cccc1OCc1ccccc1>>O=Cc1c(OCc2ccccc2)cccc1OCc1ccccc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US20160251340A1,CC(C)(C)OC(=O)NC(C)(C)C(=O)O.CCC1OCc2cccc(Oc3ccc(N)cn3)c21>>CCC1OCc2cccc(Oc3ccc(NC(=O)C(C)(C)NC(=O)OC(C)(C)C)cn3)c21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20060257987A1,C=C(c1ccccc1)c1cccc(CC)c1>>CCc1cccc(C(C)c2ccccc2)c1,[Pd],CCO,CCOCC,,,test
US20020022624A1,CI.COc1ccccc1N1CCN(C(=O)CCc2c(-c3ccc(Cl)cc3)[nH]c3ccc(Cl)cc23)CC1>>COc1ccccc1N1CCN(C(=O)CCc2c(-c3ccc(Cl)cc3)n(C)c3ccc(Cl)cc23)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US20160145212A1,COC(=O)CBr.Oc1ccc(-c2cc(-c3ccccc3)c3ccccc3n2)cc1>>COC(=O)COc1ccc(-c2cc(-c3ccccc3)c3ccccc3n2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090048258A1,CC(C)(C)C(=O)CC#N.CC(C)(C)c1ccc(NN)cc1>>CC(C)(C)c1ccc(-n2nc(C(C)(C)C)cc2N)cc1,,CO,,CCOC(C)=O,Cl,test
US20090176778A1,COC(=O)c1nc2c(C(F)(F)F)cc(-c3cn[nH]c3)cn2c1-c1cn[nH]c1>>O=C(O)c1nc2c(C(F)(F)F)cc(-c3cn[nH]c3)cn2c1-c1cn[nH]c1,,C1CCOC1,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[Na+].[OH-],test
US20130059834A1,CS(=O)(=O)OC1CN(C(c2ccccc2)c2ccccc2)C1.C[Si](C)(C)CCOCn1cc(C=O)c2nc(-c3n[nH]c4cc(F)ccc34)cnc21>>C[Si](C)(C)CCOCn1cc(C=O)c2nc(-c3nn(C4CN(C(c5ccccc5)c5ccccc5)C4)c4cc(F)ccc34)cnc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05977098,COc1cccc(-c2sc3ccccc3c2Oc2ccc(OCc3ccccc3)cc2)c1>>COc1cccc(-c2sc3ccccc3c2Oc2ccc(O)cc2)c1,[Pd],CCO,CCOC(C)=O,Cl,,test
US04871877,CC(C)(C)C1=CC(O)(C(F)(F)F)C(=O)C(C(C)(C)C)=C1>>CC(C)(C)c1cc(C(C)(C)C)c(O)c(C(F)(F)F)c1,,O,,[Al],,test
US20070208007A1,CCCN(CCC)Cc1ccc(C(=O)Nc2cc(C#N)ccc2N)cc1.CI>>CCCN(CCC)Cc1ccc(-c2nc3ccc(C#N)cc3n2C)cc1,,C1CCOC1,,[H-].[Na+],,test
US20050215574A1,COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC1CCCN(C(=O)OC(C)(C)C)C1>>COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC1CCCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20010021718A1,CN(C)C(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1>>CN(C)C(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)O)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110190257A1,C=COCCONC(=O)c1ccc2cnsc2c1Nc1ccc(I)cc1F>>O=C(NOCCO)c1ccc2cnsc2c1Nc1ccc(I)cc1F,,CO,,Cl,,test
US20120225867A1,N#C[Cu].N#Cc1ccc(-c2c(Br)cnn2C2CCCCO2)cc1Cl>>N#Cc1ccc(-c2c(C#N)cnn2C2CCCCO2)cc1Cl,,CN(C)C=O,,,,test
US05691384,CC(=O)Nc1ccc(C(=O)c2ccccc2)cc1.CCN(CC)CCCl>>CCN(CC)CCN(C(C)=O)c1ccc(C(=O)c2ccccc2)cc1,,CC(C)=O,,Cl,[K+].[OH-],test
US20120101079A1,COCC#Cc1nc(N2CCOCC2)cc(C)c1C(=O)OC>>COCCCc1nc(N2CCOCC2)cc(C)c1C(=O)OC,[Pd],CO,,,,test
US20080015199A1,COC(=O)N=C(SC)C(=Nc1ccc(-c2noc(C)n2)cc1)c1cc(OC)c(OC)cc1CC#N.NNc1ncccn1>>COc1cc(C(Nc2ccc(-c3noc(C)n3)cc2)c2nn(-c3ncccn3)c(=O)[nH]2)cc(CC#N)c1OC,,CN(C)C=O,,CCN(CC)CC,,test
US20140087992A1,CC(C)(C)OC(=O)[C@@H](CCC(F)(F)F)[C@@H](CCC(F)(F)F)C(=O)NC1N=C(c2cccc(F)c2)c2cccc(CO)c2NC1=O>>O=C1Nc2c(CO)cccc2C(c2cccc(F)c2)=NC1NC(=O)[C@H](CCC(F)(F)F)[C@H](CCC(F)(F)F)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US04645771,Br.Oc1ccc(CN2CC=CCC2)cc1>>Br.Oc1ccc(CN2CC=CCC2)cc1,,CC(C)=O,,,,test
US20070167443A1,CON(C)C(=O)c1cn(Cc2cccc(C)n2)c2ccccc2c1=O.Cc1ccc([Mg]Br)nc1>>Cc1ccc(C(=O)c2cn(Cc3cccc(C)n3)c3ccccc3c2=O)nc1,,C1CCOC1,,,,test
US20130196993A1,CC(C)(C)OC(=O)NCC(=O)O.Nc1ccnc2occc12>>CC(C)(C)OC(=O)NCC(=O)Nc1ccnc2ccoc12,,CC#N,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030055071A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=S1(=O)CCNCCN1>>CC(C)(C)OC(=O)N1CCNS(=O)(=O)CC1,,c1ccncc1,,,,test
US04602006,C#CC(Br)[Si](C)(C)C.CCOC(=O)C(C)Cc1ccccc1>>CCOC(=O)C(C)(CC#C[Si](C)(C)C)Cc1ccccc1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20070099915A1,C[Si](C)(C)CCOCON1CCc2c(ncc3c2c(CN2CCCCC2)cn3Cc2ccc(F)cc2)C1=O>>O=C1c2ncc3c(c(CN4CCCCC4)cn3Cc3ccc(F)cc3)c2CCN1O,,CO,,Cl,,test
US04937268,BrC(Br)(Br)Br.OCCCOCCOCCCOc1ccccc1>>BrCCCOCCOCCCOc1ccccc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110319378A1,C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)C(C)=O)C1=O.C[Si](C)(C)C(F)(F)F>>C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)C(C)(O)C(F)(F)F)C1=O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140243283A1,CC(=O)OC[C@H]1O[C@H](CCCc2ccc(CCC[C@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H]3OC(C)=O)cc2)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>OC[C@H]1O[C@H](CCCc2ccc(CCC[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)cc2)[C@@H](O)[C@@H](O)[C@@H]1O,,CO,,CO[Na],,test
US20150045368A1,CC1(C)OC(=O)N[C@H]1c1ccc(F)cc1.O=C(Nc1cccc2cccnc12)c1ccc(I)cc1>>CC1(C)OC(=O)N(c2ccc(C(=O)Nc3cccc4cccnc34)cc2)[C@H]1c1ccc(F)cc1,[Cu]I,C1COCCO1,,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20140163001A1,CC(C)(C)n1ncc(-c2nc(CC(=O)O)cs2)c1-c1ccc(F)cc1.NCc1ccc(-n2ccnc2)cc1>>CC(C)(C)n1ncc(-c2nc(CC(=O)NCc3ccc(-n4ccnc4)cc3)cs2)c1-c1ccc(F)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040009965A1,Brc1cncnc1.C[Sn](C)(C)c1cc2nccc(Cl)c2s1>>Clc1ccnc2cc(-c3cncnc3)sc12,,Cc1ccccc1,,,,test
US04975435,CCCCCc1scc(C(=O)OC)c1N.CCCN1CC(=O)C(C(=O)OCC)C1=O.CCCN1CC(=O)CC1=O>>CCCCCc1scc(C(=O)OC)c1NC1=CC(=O)N(CCC)C1.CCCN1CC(=O)CC1=O,,CC#N,Cc1ccccc1,O,,test
US20060229336A1,Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=NC#N)Oc2ccccc2)CC1.NN>>Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(c2nc(N)n[nH]2)CC1,,CC(C)O,,,,test
US20150299125A1,Cc1cc(Nc2cc(C(F)F)ccn2)nc(-c2ccc([C@](C)(O)[C@@H]3CC[C@@H](C(=O)OC[C@@H]4COC(C)(C)O4)CC3)nc2)c1>>Cc1cc(Nc2cc(C(F)F)ccn2)nc(-c2ccc([C@](C)(O)[C@@H]3CC[C@@H](C(=O)OC[C@@H](O)CO)CC3)nc2)c1,,O,O=C(O)C(F)(F)F,Cc1ccccc1,,test
US06313071B1,C#CC(C)O.COC(=O)NCc1cc(Br)ccc1F>>COC(=O)NCc1cc(C#CC(C)O)ccc1F,[Cu]I,CCN(CC)CC,,[Cl-].[Na+],,test
US05262377,COc1ccc(OCCCC(=O)O)cc1.O=S(Cl)Cl>>COc1ccc(OCCCC(=O)Cl)cc1,,O,,c1ccccc1,,test
US20130053366A1,CC(C)(O)CCl.Cc1ccc2c(c1)c1c(n2CC(O)c2ccncc2)CCNC1>>Cc1ccc2c(c1)c1c(n2CC(O)c2ccncc2)CCN(CC(C)(C)O)C1,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20100130495A1,Cc1nccn1-c1ccc(Nc2nc3c(c(N(CCO)Cc4ccccc4)n2)CN(C(=O)OC(C)(C)C)CC3)cc1>>Cc1nccn1-c1ccc(Nc2nc3c(c(N(CCO)Cc4ccccc4)n2)CNCC3)cc1,,CO,,Cl,,test
US04615970,C(=Nc1ccccc1)=Nc1ccccc1.CCOC(=O)c1ccc(NN)cc1>>CCOC(=O)c1ccc(NNC(=Nc2ccccc2)Nc2ccccc2)cc1,,C1CCOC1,,,,test
US20030125317A1,COC(=O)C[C@@H]1Cc2ccc(OCCCNc3ncccn3)cc2CN(Cc2ccc(C(F)(F)F)cc2)C1=O>>COC(=O)C[C@@H]1Cc2ccc(OCCCNC3=NCCCN3)cc2CN(Cc2ccc(C(F)(F)F)cc2)C1=O,[Pd],CC(=O)O,,Cl,[H][H],test
US04440772,CC(C)C[C@@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C=C4c5cccc6[nH]cc(c56)C[C@@H]4N(C)C3)(C(C)C)C(=O)N12.CS(=O)(=O)O>>CC(C)C[C@@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C=C4c5cccc6[nH]cc(c56)C[C@@H]4N(C)C3)(C(C)C)C(=O)N12.CS(=O)(=O)O,,CCO,,CCOCC,,test
US04994569,O=C=Nc1ccccc1.OC1CN=C(c2ccc(OC(F)(F)F)cc2)OC1c1ccccc1>>O=C(Nc1ccccc1)OC1CN=C(c2ccc(OC(F)(F)F)cc2)OC1c1ccccc1,,ClCCCl,,,,test
US20090286812A1,Cc1ncccc1Oc1ncnc2c1cnn2C1CCN(C(=O)OC(C)C)CC1.Cl>>Cc1ncccc1Oc1ncnc2c1cnn2C1CCN(C(=O)OC(C)C)CC1.Cl,,CCOCC,,,,test
US20140018537A1,CC(C)(C)OC(=O)N1CCC(c2ccc(COc3cccc([N+](=O)[O-])c3)nc2)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccc(COc3cccc(N)c3)nc2)CC1,[Zn],CCO,,[Ca+2].[Cl-].[Cl-],,test
US20040229844A1,COC(=O)C(C(=O)OC)C1CCn2c1cc1c(SC)nccc12>>COC(=O)CC1CCn2c1cc1c(SC)nccc12,,O,,CS(C)=O,[Cl-].[Na+],test
US20070276011A1,COc1ccc(C=O)cc1[N+](=O)[O-].O=C1CSC(=O)N1Cc1ccc(Cl)c(Cl)c1>>COc1ccc(C=C2SC(=O)N(Cc3ccc(Cl)c(Cl)c3)C2=O)cc1[N+](=O)[O-],,CCOC(C)=O,Cc1ccccc1,C1CCNCC1,CC(=O)O,test
US20150018363A1,Cc1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cn12.Fc1ccc(CBr)c(F)c1>>Cc1c(C2CC2)nc2ccc(-n3ccc(OCc4ccc(F)cc4F)cc3=O)cn12,,C1CCOC1,,[H-].[Na+],,test
US20150376160A1,CC(C)(C)OC(=O)c1ccsc1Br.CCOC(=O)C1(c2ccc(-c3ccc(B4OC(C)(C)C(C)(C)O4)cc3OC)cc2)CC1CC>>CCOC(=O)C1(c2ccc(-c3ccc(-c4sccc4C(=O)OC(C)(C)C)cc3OC)cc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20050049236A1,CCCC(=O)OC(=O)CCC.COc1cc(OC)c(N2CCCC2)cc1/C=C/C(=O)c1ccc(S(N)(=O)=O)cc1>>CCCC(=O)NS(=O)(=O)c1ccc(C(=O)/C=C/c2cc(N3CCCC3)c(OC)cc2OC)cc1,CN(C)c1ccncc1,C1CCOC1,CN(C)C=O,CCN(CC)CC,,test
US20110280804A1,O=C(OCCCc1ccc2c(c1)sc(=O)n2CCN1CCCCCC1)c1ccccc1>>O=c1sc2cc(CCCO)ccc2n1CCN1CCCCCC1,,CO,O,[Na+].[OH-],,test
US20020156054A1,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2cccc(O[Si](C)(C)CC(CC)CC)c2)=CCC3(C)C)cc1>>CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2cccc(O)c2)=CCC3(C)C)cc1,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090264445A1,CC(C)C[C@@H](C(=O)O)N1CC(Oc2cccc(Cl)c2F)=CC1=O.CC1(C)OC[C@@H](Cn2ccc(N)n2)O1>>CC(C)C[C@@H](C(=O)Nc1ccn(C[C@@H]2COC(C)(C)O2)n1)N1CC(Oc2cccc(Cl)c2F)=CC1=O,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20060276655A1,CC(C)[Si](S[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C.N#CC1(CC2CC2)CC=C(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)CC1>>CC(C)[Si](SC1=CCC(C#N)(CC2CC2)CC1)(C(C)C)C(C)C,,C1CCOC1,Cc1ccccc1,[H-].[Na+],,test
US20070117856A1,CC(C)Oc1c(OC(C)C)c(=O)c1=O.O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1>>CC(C)Oc1c(N2CCN(C(=O)c3ccc(/C=C/c4n[nH]c5ccccc45)cc3)CC2)c(=O)c1=O,,CO,,CCN(CC)CC,,test
US05728879,Cc1ccc(S(=O)(=O)Cl)cc1.Clc1ccccc1>>Cc1ccc(S(=O)(=O)c2ccc(Cl)cc2)cc1,,O,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20130231327A1,COC(=O)c1ccc2c(c1)[C@H](NCC(F)(F)F)CC2.O=C(Cl)c1ccccc1Cl>>COC(=O)c1ccc2c(c1)[C@H](N(CC(F)(F)F)C(=O)c1ccccc1Cl)CC2,,ClCCl,,,,test
US06187777B1,CC1CC(c2ncc3nc(-c4ccn(S(=O)(=O)c5ccccc5)c4)cc-3[nH]2)CCN1.CO.Cl>>CC1CC(c2ncc3nc(-c4ccn(S(=O)(=O)c5ccccc5)c4)cc-3[nH]2)CCN1.Cl.O,,CO,,CCOC(C)=O,,test
US04353919,COc1ccc2sc(=O)n(C(C)=O)c2c1>>COc1ccc2sc(=O)[nH]c2c1,,CCO,Cl,,,test
US04727158,CCCCCCCCCCCCc1ccc(NC(C)=O)c([N+](=O)[O-])c1>>CCCCCCCCCCCCc1ccc(N)c([N+](=O)[O-])c1,,O,,CCO,[K+].[OH-],test
US20080292588A1,CS(=O)(=O)Cl.CS1(=O)=NC(C2=C(O)C3C4CCC(C4)C3N(Cc3ccc(F)cc3)C2=O)=Nc2ccc(N)cc21>>CS(=O)(=O)Nc1ccc2c(c1)S(C)(=O)=NC(C1=C(O)C3C4CCC(C4)C3N(Cc3ccc(F)cc3)C1=O)=N2,,CC(C)=O,,c1ccncc1,,test
US20050148627A1,CCOC(=O)C1=Cc2ccc(C(C)(C)C=O)cc2OC1C(F)(F)F>>CCOC(=O)C1=Cc2ccc(C(C)(C)CO)cc2OC1C(F)(F)F,,CO,,CC(=O)O,[BH4-].[Na+],test
US20090298794A1,COc1cc(-n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)ccc1OC[C@H](OP(=O)(OCC[Si](C)(C)C)OCC[Si](C)(C)C)C1CC1>>COc1cc(-n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)ccc1OC[C@H](OP(=O)(O)O)C1CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US03940519,CCCCCCCCCCCCCCCCCCNCCCCCCCCCCCCCCCCCC.O=C(Cl)Cl>>CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)C(=O)Cl,,Cc1ccccc1,,,,test
US20050171148A1,C=C(C)[Sn](CCCC)(CCCC)CCCC.COC(=O)[C@H](Cc1ccc(Br)s1)NC(=O)c1cc2cc(Oc3ccc(C(C)(C)C)cc3)ccc2c(CC2CCCC2)n1>>C=C(C)c1ccc(C[C@H](NC(=O)c2cc3cc(Oc4ccc(C(C)(C)C)cc4)ccc3c(CC3CCCC3)n2)C(=O)OC)s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20080031823A1,CC(=O)Cl.Nc1cc(F)ccc1Oc1ccccc1>>CC(=O)Nc1cc(F)ccc1Oc1ccccc1,,c1ccncc1,,,,test
US20070004722A1,C1CSCCN1.CS(=O)(=O)c1nsc(Cl)n1.CS(=O)c1nsc(Cl)n1.CSc1nsc(Cl)n1.ClC(Cl)Cl>>CS(=O)(=O)c1nsc(N2CCSCC2)n1.CS(=O)c1nsc(N2CCSCC2)n1,,ClC(Cl)Cl,O,O=C(OO)c1cccc(Cl)c1,,test
US20160185785A1,N#CC(C#N)CC(=O)c1ccccc1.Nc1ccc(F)cc1>>N#Cc1cc(-c2ccccc2)n(-c2ccc(F)cc2)c1N,,CCO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20080050336A1,C[C@H](CO[Si](C)(C)C(C)(C)C)[C@H](NC1(c2ccccc2)c2ccccc2-c2ccccc21)C(=O)OCc1ccccc1>>C[C@H](CO[Si](C)(C)C(C)(C)C)[C@H](N)C(=O)O,[Pd],CCOC(C)=O,ClCCl,[H][H],,test
US20150148313A1,CC(C)S.O=Cc1cc([N+](=O)[O-])cc(F)c1F>>CC(C)Sc1c(F)cc([N+](=O)[O-])cc1C=O,,CCOC(C)=O,CN(C)C=O,,,test
US20140038999A1,C=Cc1cc2c3ccnc(C)c3c(=O)n(C)c2cc1OC[C@H](CC(C)C)NC(=O)OC(C)(C)C>>CCc1cc2c3ccnc(C)c3c(=O)n(C)c2cc1OC[C@H](CC(C)C)NC(=O)OC(C)(C)C,[Pd],CO,,[H][H],,test
US20060116406A1,C=[N+]=[N-].O=C(O)C[C@](O)(c1cnc(Sc2ccc3c(-c4ccc(F)cc4)cc(=O)oc3c2)s1)C(F)(F)F>>COC(=O)C[C@](O)(c1cnc(Sc2ccc3c(-c4ccc(F)cc4)cc(=O)oc3c2)s1)C(F)(F)F,,C1CCOC1,,,,test
US20080269220A1,CC(C)Oc1cc(CO)ccc1Cn1nc(-c2ccccc2)cc1-c1ccccc1.CCOC(=O)CCc1c(F)cc(NS(=O)(=O)c2ccccc2[N+](=O)[O-])cc1F>>CCOC(=O)CCc1c(F)cc(N(Cc2ccc(Cn3nc(-c4ccccc4)cc3-c3ccccc3)c(OC(C)C)c2)S(=O)(=O)c2ccccc2[N+](=O)[O-])cc1F,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05516774,Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1.O=S(=O)(Cl)c1ccccc1Cl>>O=C(c1ccc(NS(=O)(=O)c2ccccc2Cl)cc1)N1Cc2cccn2Cc2ccccc21,,ClCCl,,CCN(CC)CC,,test
US20130085144A1,N#Cc1cc(S(=O)(=O)Nc2cc(F)cc(F)c2)cnc1Cl.NN>>Nc1n[nH]c2ncc(S(=O)(=O)Nc3cc(F)cc(F)c3)cc12,,CC(C)O,,,,test
US20120149699A1,Cc1c(NS(=O)(=O)c2ccc(-n3cccn3)cc2)nc2ccc(Cl)cn12.Fc1ccc(CBr)cc1C(F)(F)F>>Cc1c(N(Cc2ccc(F)c(C(F)(F)F)c2)S(=O)(=O)c2ccc(-n3cccn3)cc2)nc2ccc(Cl)cn12,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],,test
US04840971,BrCc1cccc(Oc2ccccc2)c1.OCC(c1ccc(F)cc1)C(F)(F)F>>Fc1ccc(C(COCc2cccc(-c3ccccc3)c2)C(F)(F)F)cc1,,COCCOCCOC,,[Cs+].[F-],,test
US20090215759A1,CCO.COc1cc(Nc2nc(C)cc(Cl)n2)ccc1-n1cnc(C)c1>>CCOc1cc(C)nc(Nc2ccc(-n3cnc(C)c3)c(OC)c2)n1,,CCO,,C,C[O-].[Na+],test
US20050096312A1,CCOc1cc(N2CCN(C)CC2)c2oc(C(=O)Cl)cc(=O)c2c1.Nc1ccc(N2CCOCC2)cc1>>CCOc1cc(N2CCN(C)CC2)c2oc(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(=O)c2c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US06610692B1,Cc1cc(C(=O)N(CC(C)C)CC(C)C)c(O)c(=O)n1CC(=O)OC(C)(C)C>>Cc1cc(C(=O)N(CC(C)C)CC(C)C)c(O)c(=O)n1CC(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070010529A1,CCN(CC)CC.CCN=C=NCCCN(C)C.CCOC(C)=O.CN(C)C=O.On1nnc2ccccc21>>Cc1cccc(C)c1N1C(=O)CCNC1=O,,CCOC(C)=O,,O,,test
US20110143435A1,CCCCCCCCCCCCSC(=S)SC(C)(C)C(=O)Cl.[N-]=[N+]=NCCCO>>CCCCCCCCCCCCSC(=S)SC(C)(C)C(=O)OCCCN=[N+]=[N-],,ClCCl,,CCN(CC)CC,,test
US05155259,CCOC(=O)CCc1ccc(O)c(-c2cc(CCC(=O)OCC)ccc2O)c1.CI.CN(C)C=O>>CCOC(=O)CCc1ccc(OC)c(-c2cc(CCC(=O)OCC)ccc2OC)c1,[Cu],,,O=C([O-])[O-].[K+].[K+],,test
US20130317074A1,Cc1nn(-c2ccccc2OCc2ccccc2)c(C)c1F>>Cc1nn(-c2ccccc2O)c(C)c1F,[Pd],CO,,,,test
US06586475B1,COC(=O)c1ccc(NC(=O)c2ccc(-c3ccccc3)cc2)cc1>>O=C(O)c1ccc(NC(=O)c2ccc(-c3ccccc3)cc2)cc1,,C1CCOC1,Cl,CO,[Na+].[OH-],test
US20050038245A1,CC(=O)OC(C)=O.OCCOc1ccc(-c2nnnc(-c3cccc4ccccc34)c2-c2cccc3ccccc23)c(O)c1>>CC(=O)OCCOc1ccc(-c2nnnc(-c3cccc4ccccc34)c2-c2cccc3ccccc23)c(O)c1,,ClCCl,,CCN(CC)CC,CN(C)c1ccccn1,test
US20050165042A1,COc1cccc(C(=O)CBr)c1.N#Cc1cc2c(cc1O)CCCC2=O>>COc1cccc(C(=O)c2oc3cc4c(cc3c2N)C(=O)CCC4)c1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20020007071A1,C(=NC1CCCCC1)=NC1CCCCC1.Cc1cccc2c1nc(COc1ccc(Cl)cc1)n2CCC(C)C(=O)O.c1ccc2c(c1)CCCC2>>Cc1cccc2c1nc(COc1ccc(Cl)cc1)n2CCC(C)C(=O)NC1CCCc2ccccc21,,CN(C)C=O,,On1nnc2ccccc21,,test
US20090264406A1,COC(=O)c1ccc([N+](=O)[O-])c(NCCN2CCCC2)c1>>COC(=O)c1ccc(N)c(NCCN2CCCC2)c1,[Ni],C1CCOC1,CO,,,test
US20040002526A1,O=C1CSC(=S)N1Cc1ccccc1C(F)(F)F.O=Cc1ccc(-c2ccc(C(=O)O)cc2)o1>>O=C(O)c1ccc(-c2ccc(C=C3SC(=S)N(Cc4ccccc4C(F)(F)F)C3=O)o2)cc1,C1CCNCC1,CCO,,Cl,,test
US06174881B1,N#CCN=C(c1ccccc1F)c1ccsc1N>>NC1=Nc2sccc2C(c2ccccc2F)=NC1,,CC(=O)O,,,,test
US20150299179A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NC(=O)[O-])ns2)cc1C#N.Cl>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@@H]4N)ns2)cc1C#N.Cl,,C1COCCO1,CCOCC,,,test
US05128351,CCCCCCCCCCCCCCCCOc1ccc(OCC(=O)Nc2ccccc2CBr)cc1.Cc1cncs1>>CCCCCCCCCCCCCCCCOc1ccc(OCC(=O)Nc2ccccc2C[n+]2csc(C)c2)cc1.[Br-],,Cc1ccccc1,,,,test
US20090176823A1,CC(=O)Cl.CCOC(=O)C1=C(c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)nc2)C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]1N2C(=O)OC(C)(C)C(Cl)(Cl)Cl>>CCOC(=O)C1=C(c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)nc2)C[C@@H]2CN(C(C)=O)C[C@H]1N2C(=O)OC(C)(C)C(Cl)(Cl)Cl,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20050209260A1,COc1cccc(O)c1C(C)=O.C[Mg]Br>>COc1cccc(O)c1C(C)(C)O,,C1CCOC1,CCOCC,O,[Cl-].[NH4+],test
US20040138462A1,CC(=O)Cl.CC(C)(C)OC(=O)N(CCc1ccc(S(=O)(=O)c2ccc(C(N)=NO)cc2)cc1)C[C@H](O)c1cccc(Cl)c1>>Cc1nc(-c2ccc(S(=O)(=O)c3ccc(CCN(C[C@H](O)c4cccc(Cl)c4)C(=O)OC(C)(C)C)cc3)cc2)no1,,c1ccncc1,,,,test
US20050165065A1,CN(C(=O)NC(c1ccccc1)c1ccccc1)C1CCN(C(=O)c2ccccc2)C1>>CN(C(=O)NC(c1ccccc1)c1ccccc1)[C@@H]1CCNC1,[Pd],CO,,,,test
US05262390,FCCCBr.O=c1[nH]nnn1-c1ccc(OCc2ccc(F)cc2)cc1F>>O=c1n(CCCF)nnn1-c1ccc(OCc2ccc(F)cc2)cc1F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160039834A1,CNC.Cc1noc(C)c1-c1nc(-c2cc(OC[C@H]3CO3)ccc2Cl)nc(N[C@H]2CCN(C3CC3)[C@@H](C)C2)c1C>>Cc1noc(C)c1-c1nc(-c2cc(OC[C@H](O)CN(C)C)ccc2Cl)nc(N[C@H]2CCN(C3CC3)[C@@H](C)C2)c1C,,CO,O,,,test
US20120184548A1,COc1cc2cc(C(=O)Nc3cc(C(=O)NC(CNC(=O)OC(C)(C)C)c4cccc(Cl)c4)ccc3C)c(=O)[nH]c2cc1OC>>COc1cc2cc(C(=O)Nc3cc(C(=O)NC(CN)c4cccc(Cl)c4)ccc3C)c(=O)[nH]c2cc1OC,,ClCCl,O=C(O)C(F)(F)F,,,test
US05512575,COC(=O)C12CC(c3ccc(Cl)cc31)c1ccc(Cl)cc12>>O=C(O)C12CC(c3ccc(Cl)cc31)c1ccc(Cl)cc12,,C1CCOC1,CO,O,[Li+].[OH-],test
US20120245144A1,C1CCN(CC2CCCN2)CC1.Clc1cc2c(cn1)-c1nc(-c3ccccn3)cn1CCO2>>c1ccc(-c2cn3c(n2)-c2cnc(N4CCCC4CN4CCCCC4)cc2OCC3)nc1,,CN1CCCC1=O,,,,test
US20130184257A1,CC(C)(C)OC(=O)N1CCC(N2CCC[C@H](Nc3ccc(S(C)(=O)=O)cc3F)C2=O)CC1.Cl>>CS(=O)(=O)c1ccc(N[C@H]2CCCN(C3CCNCC3)C2=O)c(F)c1.Cl,,C1COCCO1,ClCCl,,,test
US20100029678A1,O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.O=[N+]([O-])OC1CCNCC1>>O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCC(O[N+](=O)[O-])CC1,,C1CCOC1,CC#N,CCN(CC)CC,Cl,test
US20130324684A1,CCCCCCc1ccc(-c2cccs2)s1.O=C1CCC(=O)N1Br>>CCCCCCc1ccc(-c2ccc(Br)s2)s1,,CN(C)C=O,,,,test
US20040106638A1,CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)N.CS(=O)(=O)Cl>>CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)NS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US03952001,C=CCOCCSc1nc[nH]n1.CCN(CC)C(=O)Cl>>C=CCOCCSc1ncn(C(=O)N(CC)CC)n1,,C1CCOC1,,CCN(CC)CC,,test
US04588819,O=C(OCc1ccccc1)N1C[C@H](C2CCCCC2)C[C@H]1CO.O=O>>O=C(O)[C@@H]1C[C@@H](C2CCCCC2)CN1C(=O)OCc1ccccc1,[Pt],O,,C1COCCO1,O=C([O-])O.[Na+],test
US20150329538A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.Cc1cc2cccc(Br)c2nc1Oc1ccccc1>>CC(=O)c1cccc2cc(C)c(Oc3ccccc3)nc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20110207716A1,CC[C@@H]1C(=O)N(C)c2cnc(-c3sc(N)nc3-c3ccc(F)cc3)nc2N1C(C)C.N#C[Cu]C#N>>CC[C@@H]1C(=O)N(C)c2cnc(-c3sc(C#N)nc3-c3ccc(F)cc3)nc2N1C(C)C,,CC#N,,CC(C)CCON=O,,test
US20070135467A1,Fc1cc(C(F)(F)F)cc(C(Cc2ccccc2)(N=C=S)c2ccc(Cl)cn2)c1.[N-]=[N+]=NCC(=O)c1ccccc1>>Fc1cc(C(F)(F)F)cc(C(Cc2ccccc2)(Nc2ncc(-c3ccccc3)o2)c2ccc(Cl)cn2)c1,,C1COCCO1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20040132994A1,O=CNc1ccnn1CCF>>Nc1ccnn1CCF,,CO,,Cl,,test
US20160060273A1,CCOC(=O)C1(C)CCN(C2=NOC3(C2)CN(Cc2cc(C4CC4)c(-c4ccc(F)cc4)cc2OCC)C3)CC1>>CCOc1cc(-c2ccc(F)cc2)c(C2CC2)cc1CN1CC2(CC(N3CCC(C)(C(=O)O)CC3)=NO2)C1,,CCO,,Cl,[Na+].[OH-],test
US20090093497A1,CI.O=C(O)[C@@H]1CCC[C@H]1C(=O)Nc1ccc(-c2ccc([N+](=O)[O-])cc2)cc1>>CN(C(=O)[C@@H]1CCC[C@H]1C(=O)O)c1ccc(-c2ccc([N+](=O)[O-])cc2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20050124664A1,O=C(O)c1c(O)c(Cl)cc(Cl)c1Cl.O=S(Cl)Cl>>O=C(Cl)c1c(O)c(Cl)cc(Cl)c1Cl,,ClCCl,,CN(C)C=O,,test
US20090297472A1,CCCS(=O)(=O)[C@@]1(c2ccc(-c3ccccc3)cc2)C[C@@H](C(=O)OC)N(C(=O)OCc2ccccc2)C1>>CCCS(=O)(=O)[C@]1(c2ccc(-c3ccccc3)cc2)CN[C@H](C(=O)OC)C1,,CC#N,,C[Si](C)(C)I,,test
US04732982,CCCCC(=O)c1cc(C#N)c(=O)[nH]c1C.CON>>CCCCC(=NOC)c1cc(C#N)c(=O)[nH]c1C,,CCO,,Cl,c1ccncc1,test
US20100267699A1,CC(C)(C)OC(=O)N1CCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1>>CC(C)(C)OC(=O)N1CCN(C2=Nn3c(nnc3C(F)(F)F)CC2)CC1,[Pd],CO,,,,test
US20140141034A1,CC(=O)c1ccc(N)cc1.CCOC(=O)NN.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCOC(=O)NNC(=O)Nc1ccc(C(C)=O)cc1,,C1CCOC1,O,CCN(CC)CC,,test
US20050261333A1,Clc1cnc2[nH]c(-c3ccc(OCCN4CCOCC4)cc3)nc2c1Cl.OCCN1CCCC1>>Clc1cnc2nc(-c3ccc(OCCN4CCOCC4)cc3)[nH]c2c1OCCN1CCCC1,,CC#N,,[H-].[Na+],,test
US05051413,CC(=C[C@@H](NC(=O)OC(C)(C)C)C(=O)O)CP(=O)(OC(C)C)OC(C)C.CCO>>CCOC(=O)[C@@H](C=C(C)CP(=O)(OC(C)C)OC(C)C)NC(=O)OC(C)(C)C,,CCO,ClCCl,c1ccncc1,,test
US20130116245A1,CC[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1ccc([N+](=O)[O-])nc1>>CC[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1ccc(N)nc1,[Pd],CO,,,,test
US20120157433A1,CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)Nc2cc(-c3ccc(Cl)c(N(CC4CCOCC4)C(=O)OC(C)(C)C)c3)c(Cl)cn2)C1>>O=C(Nc1cc(-c2ccc(Cl)c(NCC3CCOCC3)c2)c(Cl)cn1)[C@@H]1CCCNC1,,C1COCCO1,CO,Cl,,test
US20020004513A1,CC(C)(C)OC(=O)N1CCC(NCc2ccc(Cl)cc2Cl)CC1.COc1ccc(CC(=O)Cl)cc1>>COc1ccc(CC(=O)N(Cc2ccc(Cl)cc2Cl)C2CCN(C(=O)OC(C)(C)C)CC2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20150099883A1,CC(C)(N)c1ccccn1.O=C(NOc1ccc2ncsc2c1)Oc1ccccc1>>CC(C)(NC(=O)NOc1ccc2ncsc2c1)c1ccccn1,,C1CCOC1,,CCN(CC)CC,,test
US20130102609A1,CC(=O)c1ccc(O)c(Br)c1.COC(=O)CBr>>COC(=O)COc1ccc(C(C)=O)cc1Br,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160137595A1,CC(C)C(Oc1ccc(Br)cc1N)C(C)C.Cc1ccc(N=C=O)cc1>>Cc1ccc(NC(=O)Nc2cc(Br)ccc2OC(C(C)C)C(C)C)cc1,,C1CCOC1,,,,test
US20100286390A1,C[Mg]Br.O=Cc1ccnc(F)c1Cl>>CC(O)c1ccnc(F)c1Cl,,C1CCOC1,,[Cl-].[NH4+],,test
US20120225854A1,C[C@H]1COCCN1C[C@H]1CN(S(=O)(=O)c2cccs2)CCN1.O=S(=O)(Cl)c1nccs1>>C[C@H]1COCCN1C[C@H]1CN(S(=O)(=O)c2nccs2)CCN1,,ClCCl,,CCN(CC)CC,,test
US20140179670A1,CNC.Cn1c(=O)cc(Cl)n(-c2cccc(C(F)(F)F)c2)c1=O>>CN(C)c1cc(=O)n(C)c(=O)n1-c1cccc(C(F)(F)F)c1,,CC(C)O,,,,test
US20120295875A1,CCCBr.OB1OCc2ccc(O)cc21>>CCCOc1ccc2c(c1)B(O)OC2,,CN(C)C=O,,Cl,[H-].[Na+],test
US20160227779A1,O=P(Cl)(Cl)Cl.O=c1cnc2cc(C(F)(F)F)ccc2[nH]1>>FC(F)(F)c1ccc2nc(Cl)cnc2c1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20060199962A1,CI.CNc1ccn2c(C(=O)c3ccc([N+](=O)[O-])c(OC)c3)c(C)c(C(=O)OCc3ccccc3)c2c1>>COc1cc(C(=O)c2c(C)c(C(=O)OCc3ccccc3)c3cc(N(C)C)ccn23)ccc1[N+](=O)[O-],,CN(C)C=O,ClCCl,Cl,[H-].[Na+],test
US20140243283A1,Brc1ccc2c(c1)C1(CCC3(CC1)OCCO3)c1cc(Br)ccc1-2>>O=C1CCC2(CC1)c1cc(Br)ccc1-c1ccc(Br)cc12,,C1CCOC1,O,Cl,,test
US20130274260A1,NCc1cccs1.O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(CCl)c1>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(CNCc2cccs2)c1,,C1CCOC1,,[I-].[Na+],,test
US20090318408A1,CN1C(=O)C(F)(F)CN(C2CCC2)c2nc(Nc3ccc(C(=O)N4CCC(NC(=O)OCC5c6ccccc6-c6ccccc65)CC4)cc3)ncc21>>CN1C(=O)C(F)(F)CN(C2CCC2)c2nc(Nc3ccc(C(=O)N4CCC(N)CC4)cc3)ncc21,,ClCCl,,C1CCNCC1,,test
US05389660,CCCCc1nc2cc(C(=O)OC)sc2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1>>CCCCc1nc2cc(C(=O)O)sc2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US05508430,Cl[Mg]c1ccccc1.O=C[C@@H](OCc1ccccc1)[C@H]1COC2(CCCCC2)O1>>OC(c1ccccc1)[C@@H](OCc1ccccc1)[C@H]1COC2(CCCCC2)O1,,C1CCOC1,CCOCC,[Cl-].[NH4+],,test
US06897210B2,BrCCCOC1CCCCO1.COc1cc2c(N(Cl)c3ccccc3F)ncnc2cc1O>>Fc1ccccc1N(Cl)COc1ncnc2cc(OCCCOC3CCCCO3)ccc12,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US06472386B1,COc1cc(C(N)=O)cc(OC)c1OC.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COc1cc(C(N)=S)cc(OC)c1OC,,CCOC(C)=O,,Cc1ccccc1,,test
US20110015175A1,COc1cc(Nc2nc3n(n2)CCC(=O)CC3c2ccc(F)cc2)ccc1-n1cnc(Cl)c1.C[Mg]Br.O=C(O)C(F)(F)F>>COc1cc(Nc2nc3n(n2)CC[C@](C)(O)C[C@@H]3c2ccc(F)cc2)ccc1-n1cnc(Cl)c1.O=C(O)C(F)(F)F,[Cu]I,C1CCOC1,,O=C(O)C(F)(F)F,,test
US20060111347A1,CC(NC(C)(C)C)c1ccc2c(c1)CCC[C@H]2NC(=O)[C@@H]1OC(C)(C)O[C@@H]1CS(=O)(=O)c1cccc(C(F)(F)F)c1>>CC(NC(C)(C)C)c1ccc2c(c1)CCC[C@H]2NC(=O)[C@H](O)[C@H](O)CS(=O)(=O)c1cccc(C(F)(F)F)c1,,CO,,Cl,,test
US20160122341A1,Cc1cc(OCc2ncccc2F)c2nc(C)c(C(=O)O)n2c1>>Cc1cc(OCc2ncccc2F)c2nc(C)cn2c1,,C1COCCO1,,Cl,,test
US05723666,COC(=O)c1ccc2c(c1)C(=O)CCC2(C)C>>CC1(C)CCC(=O)c2ccccc21,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20040209892A1,CNc1nccc(Oc2ccc(OCc3ccccc3)cc2)n1>>CNc1nccc(Oc2ccc(O)cc2)n1,,CCOC(C)=O,CO,,,test
US20060105999A1,COP(=O)(CNS(=O)(=O)c1ccc(F)cc1)OC>>O=P(O)(O)CNS(=O)(=O)c1ccc(F)cc1,,ClCCl,,C[Si](C)(C)Br,,test
US20110190278A1,COCCBr.COCCCCN1C(=O)C(C)(CO)Oc2cc(C(F)(F)F)c(C(=O)N(C(C)C)[C@@H]3CCCN(C(=O)OC(C)(C)C)C3)cc21>>COCCCCN1C(=O)C(C)(COCCOC)Oc2cc(C(F)(F)F)c(C(=O)N(C(C)C)[C@@H]3CCCN(C(=O)OC(C)(C)C)C3)cc21,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20090093457A1,CC#CCn1c(Br)nc2c1c(=O)[nH]c(=O)n2C.OCc1cc2ccccn2c1>>CC#CCn1c(Br)nc2c1c(=O)n(Cc1cc3ccccn3c1)c(=O)n2C,,C1CCOC1,ClCCl,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110028444A1,C[C@H]1Sc2c(C(=O)O)c(=O)c3cc(F)c(N4CCNCC4)cc3n21.N[C@@H](CCC(=O)O)C(=O)O>>C[C@H]1Sc2c(C(=O)O)c(=O)c3cc(F)c(N4CCNCC4)cc3n21.N[C@@H](CCC(=O)O)C(=O)O,,O,,,,test
US05866594,COC(=O)c1cc2c(C)ccc(C)c2[nH]1.O=C(Cl)Oc1ccccc1>>COC(=O)c1cc2c(C)ccc(C)c2n1C(=O)Oc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US06204277B1,COC(=O)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)OC>>Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(C(=O)O)C(=O)O)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20060264440A1,CCOC(=O)CN(C)C(=O)c1cc(I)ccc1N>>CN1CC(=O)Nc2ccc(I)cc2C1=O,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US04195041,CS(C)=O.Cc1ccc([N+](=O)[O-])cc1>>Nc1ccc(C=O)cc1,,CN(C)C=O,,,,test
US20100331310A1,CCOC(=O)NN=C(C)OCC.Cn1ccc(N)n1>>Cc1n[nH]c(=O)n1-c1ccn(C)n1,,CN(C)C=O,,,,test
US03937673,Clc1ccccc1Cl.O=C(O)c1ccc2c(c1)C(=O)OC2=O>>O=C(O)CCCCC(=O)O,,Clc1ccccc1Cl,,,,test
US20150246880A1,CS(=O)(=O)C1CN(Cc2ccccc2)CC1(c1cc(Cl)cc(Cl)c1)C(F)(F)F>>FC(F)(F)C1(c2cc(Cl)cc(Cl)c2)C=CN(Cc2ccccc2)C1,,Cc1ccccc1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20040092582A1,COc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(NS(C)(=O)=O)cc1)=NC(C)(C)C2.CS(=O)(=O)Cl>>COc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(N(S(C)(=O)=O)S(C)(=O)=O)cc1)=NC(C)(C)C2,,C1CCOC1,,CCN(CC)CC,O,test
US08378104B2,Brc1cccc2ncsc12.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(c2cccc3ncsc23)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20090131398A1,CCN(CC)[C@@H]1C[C@@H](CN2C(=O)C(O)(c3ccc(Cl)cc3Cl)c3c2cc(-n2ccnn2)cc3C(F)(F)F)C1.Cl>>CCN(CC)[C@@H]1C[C@@H](CN2C(=O)C(O)(c3ccc(Cl)cc3Cl)c3c2cc(-n2ccnn2)cc3C(F)(F)F)C1.Cl,,CC#N,,O,,test
US03932429,BrBr.COc1cccc(C2(C(N)=O)CCC(=O)CC2)c1>>COc1cccc(C2(C(N)=O)CCC(=O)C(Br)C2)c1,,CC(=O)O,,,,test
US20130090323A1,C1COCCN1.Oc1ccnc(Cl)c1>>Oc1ccnc(N2CCOCC2)c1,,CC(C)O,,,,test
US20060115425A1,CC(C)(Oc1cc(C(F)(F)F)ccn1)C(=O)O.CN1CCOCC1.C[C@H](N)[C@@H](Cc1ccc(Cl)cc1)c1cccc(C#N)c1>>COc1ccc(C[C@@H](c2cccc(C#N)c2)[C@H](C)NC(=O)C(C)(C)Oc2cc(C(F)(F)F)ccn2)cc1,,ClCCl,,,,test
US20160135461A1,COC(=O)C1(C(N)=S)CCN(C(=O)Nc2cc(C(F)F)nn2C)CC1.CS(=O)(=O)Oc1cccc(Cl)c1C1CC(C(=O)CBr)=NO1>>COC(=O)C1(c2nc(C3=NOC(c4c(Cl)cccc4OS(C)(=O)=O)C3)cs2)CCN(C(=O)Nc2cc(C(F)F)nn2C)CC1,,C1CCOC1,,O,,test
US20160214964A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.COc1cc2ncnc(N(Cc3ccc(OC)c(OC)c3)c3ccc(F)c(Cl)c3)c2cc1N>>COc1cc2ncnc(N(Cc3ccc(OC)c(OC)c3)c3ccc(F)c(Cl)c3)c2cc1NC1CCN(C(=O)OC(C)(C)C)CC1,,CC(=O)O,,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130261151A1,CC(C)(C)C(=O)OCCCCn1c(Cn2c(=O)n(C3CC3)c3ccncc32)nc2nc(Cl)ccc21>>O=c1n(Cc2nc3nc(Cl)ccc3n2CCCCO)c2cnccc2n1C1CC1,,C1CCOC1,O,[Li+].[OH-],,test
US20160145244A1,Cc1cc(Nc2ncnc(Nc3ccccc3S(=O)(=O)C(C)C)n2)c2c(c1C1CCN(C(=O)[C@H](C)NC(=O)OC(C)(C)C)CC1)C[C@@H](C)O2>>Cc1cc(Nc2ncnc(Nc3ccccc3S(=O)(=O)C(C)C)n2)c2c(c1C1CCN(C(=O)[C@H](C)N)CC1)C[C@@H](C)O2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070225246A1,CC(=O)OC(C)=O.O[C@H]1[C@@H](OCc2ccccc2)O[C@H](COCc2ccccc2)[C@H]1OCc1ccccc1>>CC(=O)O[C@H]1[C@@H](OCc2ccccc2)O[C@H](COCc2ccccc2)[C@H]1OCc1ccccc1,,c1ccncc1,,,,test
US20060116364A1,COc1ccc2c(c1)CCC(c1ccccc1[N+](=O)[O-])=C2>>COc1ccc2c(c1)CCC(c1ccccc1N)C2,[Pd],C1CCOC1,CO,Cl,,test
US20160031857A1,COC(=O)COc1ccc2c(c1)N(c1nc(-c3ccc(Cl)s3)nc3c1CCC3)CC2.NC1CC1>>O=C(COc1ccc2c(c1)N(c1nc(-c3ccc(Cl)s3)nc3c1CCC3)CC2)NC1CC1,,CN(C)C=O,CO,,,test
US20080139639A1,Cc1c(C=O)cn(S(=O)(=O)c2ccccc2)c1Br.OB(O)c1ccsc1>>Cc1c(C=O)cn(S(=O)(=O)c2ccccc2)c1-c1ccsc1,,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US20110319378A1,C=CCC1CC(c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N(C(CC)CNCc2ccc(OC)cc2)C1=O>>C=CCC1CC(c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N(C(CC)CN)C1=O,,CC#N,O,,,test
US20100160324A1,O=[N+]([O-])c1ccc(Nc2c[nH]nc2-c2ccccn2)nc1>>Nc1ccc(Nc2c[nH]nc2-c2ccccn2)nc1,[Pd],CO,,,,test
US20110275633A1,Cc1ccc(C#N)c(N(C)S(C)(=O)=O)c1>>Cc1ccc(CN)c(N(C)S(C)(=O)=O)c1,[Ni],CCO,CO,N,,test
US05237055,CC(=O)OC(C)=O.CO[C@H]1[C@@H](O)[C@@H](C)O[C@H](O[C@H]2[C@H](Oc3cccc4c(O)c5c(=O)oc6ccc(C)c7c(=O)oc(c34)c5c67)O[C@H](C)[C@H](O)[C@]2(C)O)[C@@H]1N>>CO[C@H]1[C@@H](O)[C@@H](C)O[C@H](O[C@H]2[C@H](Oc3cccc4c(O)c5c(=O)oc6ccc(C)c7c(=O)oc(c34)c5c67)O[C@H](C)[C@H](O)[C@]2(C)O)[C@@H]1NC(C)=O,,CO,,O,,test
US20070219261A1,CC(C)(C)c1ccc(CNC(=O)C(F)(F)c2ccccc2)cc1>>CC(C)(C)c1ccc(CNCC(F)(F)c2ccccc2)cc1,,C1CCOC1,,,,test
US20090264440A1,COCCN(Cc1ccc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)nc1)C(=O)OC(C)(C)C>>COCCN(Cc1ccc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)nc1)C(=O)OC(C)(C)C,[Fe],CCO,O,[Cl-].[NH4+],,test
US20120264728A1,CC(=O)c1ccnc(N)n1.NO>>CC(=NO)c1ccnc(N)n1,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20130274258A1,CCc1nccc2c3cc(Br)ccc3n(C)c12.NC(=O)c1cccc(B(O)O)c1>>CCc1nccc2c3cc(-c4cccc(C(N)=O)c4)ccc3n(C)c12,,C1COCCO1,CCOC(C)=O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20030195201A1,Cc1nc2cc(O)ccc2s1.FC(F)(F)c1ccc(-c2ccnc(Cl)c2)cc1>>Cc1nc2cc(Oc3cc(-c4ccc(C(F)(F)F)cc4)ccn3)ccc2s1,[Cu]I,CN(C)C=O,,[H-].[Na+],,test
US20150073124A1,COc1ccc(C(OC(CCCNC(=O)CNC(=O)CNC(=O)OCC2c3ccccc3-c3ccccc32)OC)(c2ccccc2)c2ccccc2)cc1>>COc1ccc(C(OC(CCCNC(=O)CNC(=O)CN)OC)(c2ccccc2)c2ccccc2)cc1,,CC#N,,C1CCNCC1,,test
US20160081334A1,C#C[Si](C)(C)C.COC1=C(c2c(C)cc(N=[N+]=[N-])cc2C)C(=O)CC1CCNC(=O)c1ccccn1>>COC1=C(c2c(C)cc(-n3cc([Si](C)(C)C)nn3)cc2C)C(=O)CC1CCNC(=O)c1ccccn1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20070212569A1,CCOc1ccc2cc(Br)ccc2c1.OB(O)c1ccccc1>>CCOc1ccc2cc(-c3ccccc3)ccc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O,O=C([O-])[O-].[K+].[K+],test
US20090312551A1,C1COCCO1.ClP(Cl)Cl.O=C(O)Cc1cnc2ccccn12.OP(O)O>>O=P(O)(O)C(O)(Cc1cnc2ccccn12)P(=O)(O)O,,C1COCCO1,,,,test
US20070123504A1,CCOC(=O)CC(C)=O.O=CCC1CCCCC1>>CCOC(=O)C(=CCC1CCCCC1)C(C)=O,C1CCNCC1,CCO,CCOCC,,,test
US20110065708A1,C/C(=N\O)c1ccc2nnc(C(C)c3c(F)cc4ncccc4c3F)n2n1.N.O=C(Cl)OC(Cl)(Cl)Cl>>C/C(=N\OC(N)=O)c1ccc2nnc([C@H](C)c3c(F)cc4ncccc4c3F)n2n1,,C1CCOC1,,,,test
US20140194406A1,CCOC(=O)c1cc(-c2ccnc(N)n2)[nH]c1-c1cc(Cl)ccc1CC.O=C1CCC(=O)N1Br>>CCOC(=O)c1cc(-c2nc(N)ncc2Br)[nH]c1-c1cc(Cl)ccc1CC,,CN(C)C=O,,O,,test
US20110065681A1,CC(C)(C)OC(=O)N1CC2OC2C1.COC(=O)c1cc(O)cc(-c2ccc(C)cc2C#N)c1>>COC(=O)c1cc(OC2CN(C(=O)OC(C)(C)C)CC2O)cc(-c2ccc(C)cc2C#N)c1,,CCOC(C)=O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US09266853B2,CC#CCOc1ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)NCC(=O)OC)cc1.Cl>>CC#CCOc1ccc(C[C@H](N)C(=O)NCC(=O)OC)cc1.Cl,,CCOC(C)=O,,,,test
US20150080364A1,Clc1ccc(N2CCOCC2)c(CN2CCNCC2)c1.O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O>>O=C(ON1C(=O)CCC1=O)N1CCN(Cc2cc(Cl)ccc2N2CCOCC2)CC1,,O,,CCN(C(C)C)C(C)C,ClCCl,test
US20130150325A1,C[Si](C)(C)c1ccc(C=O)cc1.Cc1cc(C(F)S(=O)(=O)c2nc3ccccc3s2)nn1C1CCCCO1>>Cc1cc(/C(F)=C/c2ccc([Si](C)(C)C)cc2)n[nH]1,,C1CCOC1,CCOC(C)=O,[Cl-].[NH4+],C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20120253035A1,CC1(C)OCC(=O)N[C@](C)(c2cc(-c3cnn(-c4ccc(F)cc4)c3)ccc2F)C1(F)F.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC1(C)OCC(=S)N[C@](C)(c2cc(-c3cnn(-c4ccc(F)cc4)c3)ccc2F)C1(F)F,,C1COCCO1,,,,test
US20030096826A1,O=[N+]([O-])c1ccc(F)cc1OCCc1cccc2ccccc12>>Nc1ccc(F)cc1OCCc1cccc2ccccc12,[Ni],C1CCOC1,,,,test
US20140335080A1,CC(C)(c1ccc(O)cc1)c1ccc(OC[C@H](O)CO)cc1.Cc1ccc(S(=O)(=O)OC[C@H]2CO2)cc1>>CC(C)(c1ccc(OC[C@H](O)CO)cc1)c1ccc(OC[C@H]2CO2)cc1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150152046A1,CC1(C)CC(=O)C2=C(C1)NC(C(=O)[O-])CS2.CN(C)C=O.ClCCl.O=C(Cl)C(=O)Cl>>CCOC(=O)[C@@H]1CSC2=C(Cl)CC(C)(C)CC2=N1,CN(C)C=O,,,,,test
US20060004069A1,CCc1nc(CCl)cs1.O=[N+]([O-])c1ccc(O)cc1>>CCc1nc(COc2ccc([N+](=O)[O-])cc2)cs1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05665606,O=C(O)c1cccc2nc3ccccc3cc12>>O=C(O)c1cccc2nc3ccccc3cc12,,C1COCCO1,,O,O=S(Cl)Cl,test
US04256759,CCn1cccc1C(=O)CC#N.O=C=Nc1ccccc1>>CCn1cccc1C(=O)C(C#N)C(=O)Nc1ccccc1,,CCN(CC)CC,,Cc1ccccc1,,test
US20090325981A1,NNC(=S)c1ccc(Cl)cc1.O=Cc1ccccc1OC(F)F>>FC(F)Oc1ccccc1C1NN=C(c2ccc(Cl)cc2)S1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20050107339A1,CCOc1cc(C(O)c2ccc(OC)c(OCc3ccccc3)c2)ccc1OC>>CCOc1cc(C(=O)c2ccc(OC)c(OCc3ccccc3)c2)ccc1OC,O=[Mn]=O,ClCCl,,,,test
US20050049270A1,N#Cc1ccccc1CBr.O=C1Cc2ccccc2C(=O)O1>>O=c1[nH]c2c(c3ccccc13)Cc1ccccc1-2,,CC#N,,CCN(CC)CC,,test
US20050137243A1,COC(CBr)OC.O=[N+]([O-])c1ccc2[nH]ncc2c1>>COC(Cn1ncc2cc([N+](=O)[O-])ccc21)OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4c(-c5ccccc5Cl)cccc4nn23)CC1.Cl>>Cl.O=c1cc(C2CCNCC2)n2nc3cccc(-c4ccccc4Cl)c3c2[nH]1,,C1COCCO1,,,,test
US04367234,COc1ccc(Cl)cc1C1OC(=O)NC1=O.O=C=NC1CCCCC1>>COc1ccc(Cl)cc1C1OC(=O)N(C(=O)NC2CCCCC2)C1=O,CCN(CC)CC,ClCCCl,,,,test
US20050070441A1,CCN=C=O.CCOc1ccc([N+](=O)[O-])c(Oc2cc(C)[nH]n2)c1>>CCNC(=O)n1nc(Oc2cc(OCC)ccc2[N+](=O)[O-])cc1C,,CCOC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100249094A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)O)ccc3C)c(F)c12.NC1(c2ncc(F)cn2)CC1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NC4(c5ncc(F)cn5)CC4)ccc3C)c(F)c12,,CN(C)C=O,,CCN(CC)CC,,test
US20060135517A1,C1CCNCC1.Cc1cccc(-c2nc3ccccn3c2-c2ccnc(S(C)(=O)=O)n2)n1>>Cc1cccc(-c2nc3ccccn3c2-c2ccnc(N3CCCCC3)n2)n1,,CC#N,,,,test
US20060270706A1,CCOC(=O)CCCCn1cc(/C=C2\CN(C(C(=O)C3CC3)c3ccccc3F)CCC2S)nn1.Cl>>Cl.O=C(O)CCCCn1cc(/C=C2\CN(C(C(=O)C3CC3)c3ccccc3F)CCC2S)nn1,,CC#N,,Cl,,test
US20070244136A1,C[C@H](CNC(=O)CN(C)C(=O)OC(C)(C)C)Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12>>CNCC(=O)NC[C@@H](C)Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12,,O=C(O)C(F)(F)F,,,,test
US20070270587A1,CN(Cc1ccccc1)S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2.OCCCO>>CN(Cc1ccccc1)S(=O)(=O)c1ccc2c(c1)C1(OCCCO1)C(=O)N2,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20030069297A1,Cc1cc(C(=O)O)c(/C=C2\C(=O)Nc3cccc(-c4cccc(F)c4)c32)[nH]1.O=C(NC1CC1)[C@@H]1CCCNC1>>Cc1cc(C(=O)N2CCC[C@@H](C(=O)NC3CC3)C2)c(/C=C2\C(=O)Nc3cccc(-c4cccc(F)c4)c32)[nH]1,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20070078120A1,COc1cccc(C2(C#N)CCC(=O)CC2)c1>>COc1cccc(C2(C#N)CCC(O)CC2)c1,,CO,,[BH4-].[Na+],[Cl-].[NH4+],test
US20130237525A1,CI.Cc1nc2cc(C(=O)O)ccc2s1>>COC(=O)c1ccc2sc(C)nc2c1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20120252801A1,CCNC(C)(C)C(C)(C)O.O=CC=O>>CCN1CC(=O)OC(C)(C)C1(C)C,,Cc1ccccc1,,,,test
US20090036492A1,CCCCc1cc(C=O)c2ccccc2c1.COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>CCCCc1ccc2ccccc2c1CNC(=O)c1c(OC)cc(O)c2c1OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20130324514A1,BrCc1ccccc1.COc1cc(O)ccc1C=O>>COc1cc(OCc2ccccc2)ccc1C=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040067955A1,CC(C)n1nc(-c2cc(C#N)c(Cl)nc2-c2ccccc2)ccc1=O.OO>>CC(C)n1nc(-c2cc(C(N)=O)c(Cl)nc2-c2ccccc2)ccc1=O,,CS(C)=O,,CCOC(C)=O,O,test
US20130137740A1,Cn1ccc2cc(C=O)ccc21.O=C1CCC(=O)N1Cl>>Cn1cc(Cl)c2cc(C=O)ccc21,,CC#N,,,,test
US04039543,COc1c(N(C)C)cc(C(O)CS(C)(=O)=O)cc1N(C)C.N#CCCNc1ccccc1>>COc1c(N(C)C)cc(CC(C#N)=CNc2ccccc2)cc1N(C)C,,CS(C)=O,,C[O-].[Na+],,test
US20100069368A1,N#Cc1cnc(Cl)nc1.c1ccc(Cc2nnc(N3CCNCC3)c3ccccc23)cc1>>N#Cc1cnc(N2CCN(c3nnc(Cc4ccccc4)c4ccccc34)CC2)nc1,,CN1CCCC1=O,,CC#N,,test
US20080153868A1,BrC(c1ccccc1)c1ccccc1.CC(C)[Si](Oc1cccc2c1CN[C@@H]([C@H]1OC(=O)N[C@H]1Cc1cc(F)cc(F)c1)C2)(C(C)C)C(C)C>>CC(C)[Si](Oc1cccc2c1CN(C(c1ccccc1)c1ccccc1)[C@@H]([C@H]1OC(=O)N[C@H]1Cc1cc(F)cc(F)c1)C2)(C(C)C)C(C)C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20030036558A1,COC(=O)c1cc(N2CCOCC2)c(F)cc1OC>>COc1cc(F)c(N2CCOCC2)cc1C(=O)O,,CCO,,[Na+].[OH-],,test
US20110076291A1,CNc1ccc2c(c1)OCCc1sc(-c3ncnn3CC(F)(F)F)nc1-2.O=C(O)c1cn[nH]c1>>O=C(NCc1ccc2c(c1)OCCc1sc(-c3ncnn3CC(F)(F)F)nc1-2)c1cn[nH]c1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050059722A1,Cc1nn(C(=O)OC(C)(C)C)c2ccc(N)cc12.O=S(=O)(Cl)c1cccc(F)c1>>Cc1nn(C(=O)OC(C)(C)C)c2ccc(NS(=O)(=O)c3cccc(F)c3)cc12,,CCN(CC)CC,,C1CCOC1,,test
US20160039841A1,Cn1c(=O)n(CCCOC2CCCCO2)c(=O)c2c(C(O)c3ccc(Cl)cc3)c(-c3cccc(Cl)c3)sc21>>Cn1c(=O)n(CCCO)c(=O)c2c(C(O)c3ccc(Cl)cc3)c(-c3cccc(Cl)c3)sc21,,CO,Cl,,,test
US20140314669A1,COC(=O)CC(NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1ccc(O)cc1.Cc1ccc(S(=O)(=O)OCCOS(=O)(=O)c2ccc(C)cc2)cc1>>COC(=O)CC(NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1ccc(OCCOS(=O)(=O)c2ccc(C)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04665090,Cl.NS(=O)(=O)c1ccc(CCN2C(=O)c3ccccc3C2=O)s1>>Cl.NCCc1ccc(S(N)(=O)=O)s1,,CCO,,CN,,test
US05656573,COc1cc(SC)ccc1C(=O)C(C(=O)OC(C)(C)C)C(=O)C1CC1>>COc1cc(SC)ccc1C(=O)CC(=O)C1CC1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040242592A1,Nc1ccc(F)cc1F.O=C(CCl)NCc1ccccc1>>O=C(CNc1ccc(F)cc1F)NCc1ccccc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US04477466,CC(C)(C)C(=O)OC(=O)C(C)(C)C.NS(=O)(=O)c1ccc(S(=O)(=O)c2ccc(O)cc2)s1>>CC(C)(C)C(=O)Oc1ccc(S(=O)(=O)c2ccc(S(N)(=O)=O)s2)cc1,CN(C)c1ccncc1,CC(C)=O,,CCN(CC)CC,,test
US04564694,CCCC1CCC(C2CCC(C#N)CC2)CC1.O.[OH-]>>CCCC1CCC(C2CCC(C(=O)O)CC2)CC1,,CCO,,Cl,,test
US05576313,CC(=O)OC(C)=O.Cc1ccccc1CC1(N)CCN(C(=O)OC(C)(C)C)CC1>>CC(=O)NC1(Cc2ccccc2C)CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,c1ccncc1,,test
US04079041,CC1=C(C)C(=O)OC1=O.NC1CCC(O)CC1>>CC1=C(C)C(=O)N(C2CCC(O)CC2)C1=O,,ClCCl,,,,test
US05185098,Fc1ccc(C2=CCC(C3CCC4(CC3)OCCO4)CC2)cc1F>>Fc1ccc([C@@H]2CC[C@@H](C3CCC4(CC3)OCCO4)CC2)cc1F,[Ni],CCO,,[H][H],,test
US20150210630A1,CON=C(c1ncc(Cl)cc1Cl)C(C)NC(=O)c1ccccc1C(F)(F)F>>CO/N=C(\c1ncc(Cl)cc1Cl)C(C)NC(=O)c1ccccc1C(F)(F)F,,CC#N,,,,test
US20120309738A1,CC(C)(C)OC(=O)NCc1ccc(Cl)c(N)c1.O=c1ccccn1C(=S)n1ccccc1=O>>CC(C)(C)OC(=O)NCc1ccc(Cl)c(N=C=S)c1,,ClCCl,,,,test
US20080176906A1,CS(=O)(=O)O.Cc1c(C#N)c(-c2ccc(C#N)cc2)c(C)n1Cc1cnc(Cl)c(CO)c1>>CS(=O)(=O)O.Cc1c(C#N)c(-c2ccc(C#N)cc2)c(C)n1Cc1cnc(Cl)c(CO)c1,,CCOC(C)=O,,,,test
US04939262,CCOC(=O)c1c(O)cc(CC)[nH]c1=O>>CCc1cc(O)cc(=O)[nH]1,,O,,Cl,[K+].[OH-],test
US20130131016A1,C=C(Br)C(F)(F)F.OB(O)c1ccc(Cl)c(Cl)c1>>C=C(c1ccc(Cl)c(Cl)c1)C(F)(F)F,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20070123504A1,CI.O=[N+]([O-])c1ccc(NC2CC2)nc1>>CN(c1ccc([N+](=O)[O-])cn1)C1CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050171350A1,COc1nc(OC)c(C=O)c(OC)n1>>COc1nc(O)c(C=O)c(OC)n1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US04521428,FC(F)(F)c1cccc(C2=CCNCC2)c1.O=C(Cl)Cc1cccc2ccccc12>>O=C(Cc1cccc2ccccc12)N1CC=C(c2cccc(C(F)(F)F)c2)CC1,,ClCCl,,CCN(CC)CC,O,test
US20060041144A1,COC(=O)C(=O)c1ccc(Cl)cc1>>O=C(O)C(=O)c1ccc(Cl)cc1,,CCO,,Cl,[Na+].[OH-],test
US20150087646A1,CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)N=C=O)c1F.CC(C)(C)OC(=O)NNc1ccc(C#N)cc1>>CC(C)(C)C(=O)NCc1ccc(Cl)c(-c2nn(-c3ccc(C#N)cc3)c(=O)[nH]2)c1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070254931A1,CNCc1sc(NC(C)=O)nc1/C=C\c1ccc([N+](=O)[O-])cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(=O)Nc1nc(/C=C\c2ccc([N+](=O)[O-])cc2)c(CN(C)C(=O)C(F)(F)F)s1,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20130059883A1,COC(=O)c1cc(Br)cc(C(=O)N(C)OC)c1.C[Mg]Cl>>COC(=O)c1cc(Br)cc(C(C)=O)c1,,C1CCOC1,,,,test
US20100216803A1,CCOC(=O)c1cc(C)c(C=O)[nH]1.CI>>CCOC(=O)c1cc(C)c(C=O)n1C,,O,,CN(C)C=O,[H-].[Na+],test
US04150139,CS(=O)(=O)c1nnc2n1C=Cc1cc(Cl)ccc1C2>>O=c1[nH]nc2n1C=Cc1cc(Cl)ccc1C2,,C1COCCO1,,[K+].[OH-],,test
US20160177118A1,CC(=O)OCCOc1ccccc1.CC(C)C(=O)Cl>>CC(=O)OCCOc1ccc(C(=O)C(C)C)cc1,,ClCCl,O,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US04079181,CC(O)=C(C(=O)OCc1ccc([N+](=O)[O-])cc1)N1C(=O)C2N=C(COc3ccccc3)SC21.CS(=O)(=O)Cl>>CC(OS(C)(=O)=O)=C(C(=O)OCc1ccc([N+](=O)[O-])cc1)N1C(=O)C2N=C(COc3ccccc3)SC21,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US20070117854A1,O=S(Cl)Cl.OCn1ccc(C(F)(F)F)n1>>FC(F)(F)c1ccn(CCl)n1,,ClCCl,,,,test
US20040019076A1,CCOCc1nc2c(Oc3ccccc3)nc(C)cc2n1CCCCN.CS(=O)(=O)OS(C)(=O)=O>>CCOCc1nc2c(Oc3ccccc3)nc(C)cc2n1CCCCNS(C)(=O)=O,,CCN(CC)CC,ClC(Cl)Cl,,,test
US20120129870A1,CCC(CC)C(=O)Nc1ccc(N2CCNCC2)c(F)c1.C[Si](C)(C)C#N.O=Cc1ccco1>>CCC(CC)C(=O)Nc1ccc(N2CCN(C(C#N)c3ccco3)CC2)c(F)c1,,CC#N,,II,,test
US20100056597A1,COC(=O)C(O)(c1c(C)[nH]n(-c2ccccc2)c1=O)C(F)(F)F>>COC(=O)C(=C1C(=O)N(c2ccccc2)N=C1C)C(F)(F)F,,Cc1ccccc1,,O=S(Cl)Cl,,test
US20060276464A1,Cc1ccc(S(=O)(=O)c2ccccc2)cc1S(=O)(=O)Cl.NCCc1ccccc1>>Cc1ccc(S(=O)(=O)c2ccccc2)cc1S(=O)(=O)NCCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20050070441A1,CCN=C=O.Cc1cc(Oc2c(Cl)cc(C(F)(F)F)cc2Cl)n[nH]1>>CCNC(=O)n1nc(Oc2c(Cl)cc(C(F)(F)F)cc2Cl)cc1C,,CCOC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20040122244A1,COC1=C(OC)C(=O)C(Cc2ccc(C(=O)O)c(OC(C)=O)c2)=C(C)C1=O.Nc1ccncc1>>COC1=C(OC)C(=O)C(Cc2ccc(C(=O)Nc3ccncc3)c(O)c2)=C(C)C1=O,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US04906666,CCCCCC(O)c1cccc(OCCC=CCl)c1.O=C(O)CCS>>CCCCCC(O)c1cccc(OCC=CCSCCC(=O)O)c1,,CCOCC,,CO,C[O-].[Na+],test
US20150051160A1,C=CCOC(=O)[C@H](Cc1ccc(OC(=O)NCC[C@H](NC(=O)OC(C)(C)C)C(=O)O)cc1)NC(=O)OC(C)(C)C.[N-]=[N+]=NCCOCCOCCOCCN>>C=CCOC(=O)[C@H](Cc1ccc(OC(=O)NCC[C@H](NC(=O)OC(C)(C)C)C(=O)NCCOCCOCCOCCN=[N+]=[N-])cc1)NC(=O)OC(C)(C)C,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140099333A1,COc1ccc(CCl)cc1.Oc1ccc(Br)nc1>>COc1ccc(COc2ccc(Br)nc2)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140113898A1,CC(C)(CCN)S(=O)(=O)c1cccc(C(F)(F)F)c1.CN(C)C=O.COC(=O)c1cc(C(F)(F)F)nn1CCBr>>CC(C)(CCN1CCN2NC(N)(C(F)(F)F)C=C2C1=O)S(=O)(=O)c1cccc(C(F)(F)F)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04707488,CON.O=Cc1cc(Cl)cc(Cl)c1>>CON=Cc1cc(Cl)cc(Cl)c1,,CCO,c1ccncc1,Cl,,test
US20130303515A1,COc1ccc(CNS(=O)(=O)CCCN(Cc2ccc(Cl)cc2)C(=O)C2(C)CCN2C(=O)Cc2cc(C)cc(C)c2)c(OC)c1>>Cc1cc(C)cc(CC(=O)N2CCC2(C)C(=O)N(CCCS(N)(=O)=O)Cc2ccc(Cl)cc2)c1,,O=C(O)C(F)(F)F,,,,test
US20070111995A1,CC#N.CCN(C(C)C)C(C)C.Cc1cccc(C(CCC(=O)O)NC(=O)OC(C)(C)C)c1>>Cc1cccc(C(CCC(=O)N(C)C)NC(=O)OC(C)(C)C)c1,,CC#N,CCO,ClCCCl,On1nnc2ccccc21,test
US05985882,C=CCCc1cc(OCc2ccncc2)n2nccc2n1.O=C1CCC(=O)N1Br>>C=CCCc1cc(OCc2ccncc2)n2ncc(Br)c2n1,,COCCOC,O,,,test
US04011218,CN(C)C(=O)Cl.c1cnc(-c2n[nH]c(-c3cnccn3)n2)cn1>>CN(C)C(=O)n1nc(-c2cnccn2)nc1-c1cnccn1,,C1CCOC1,,[H-].[Na+],,test
US20060293310A1,CC(C)(C)OC(=O)N1CCN(c2cccnc2)CC1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N1CCN(c2ccc(Br)nc2)CC1,,CC#N,,CCOC(C)=O,[Na+].[OH-],test
US05254724,COCCOCCOCCN(OCc1ccccc1)C(=O)CCC(=O)NCCCCCN(OCc1ccccc1)C(=O)CCC(=O)NCCCCCN(OCc1ccccc1)C(C)=O>>COCCOCCOCCN(O)C(=O)CCC(=O)NCCCCCN(O)C(=O)CCC(=O)NCCCCCN(O)C(C)=O,[Pd],CO,,,,test
US04543352,BrCCCCBr.COc1cccc2c(N)cccc12>>COc1cccc2c(N3CCCC3)cccc12,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20070265306A1,CS(=O)(=O)O.Fc1cccc(O[C@H](c2ccccc2)C2CCNCC2)c1>>CS(=O)(=O)O.Fc1cccc(O[C@H](c2ccccc2)C2CCNCC2)c1,,CC(=O)CC(C)C,,,,test
US04822375,CCCCOc1cc(C=O)c([N+](=O)[O-])cc1O.ClCc1ccccc1>>CCCCOc1cc(C=O)c([N+](=O)[O-])cc1OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05959109,CC(=O)c1cc(F)ccc1O.CCOC(=O)OCC>>O=c1cc(O)c2ccccc2o1,,c1ccccc1,,[Na+].[OH-],,test
US20050131068A1,CCNCc1ccc(C(F)(F)F)cc1.CCOC(=O)[C@H](Cc1ccc(OCC(=O)O)cc1)OCC>>CCOC(=O)[C@H](Cc1ccc(OCC(=O)N(CC)Cc2ccc(C(F)(F)F)cc2)cc1)OCC,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20090264448A1,CC(=O)N(C)c1cc(C(=O)C=CN(C)C)ccc1Cl.Cc1n[nH]c(N)c1C#N>>CC(=O)N(C)c1cc(-c2ccnc3c(C#N)c(C)nn23)ccc1Cl,,CC(=O)O,,CCOC(C)=O,,test
US20090253654A1,COC(=O)[C@H]1OC(O)[C@H](OC(=O)C(C)C)[C@@H](OC(=O)C(C)C)[C@@H]1OC(=O)C(C)C.N#CC(Cl)(Cl)Cl>>COC(=O)[C@H]1O[C@H](OC(=N)C(Cl)(Cl)Cl)[C@H](OC(=O)C(C)C)[C@@H](OC(=O)C(C)C)[C@@H]1OC(=O)C(C)C,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20110218197A1,COc1nc(-c2ccccc2Cl)cc(NC(=O)c2c(Cl)c(C(C)(C)C)nn2C)c1[N+](=O)[O-]>>COc1nc(-c2ccccc2Cl)cc(NC(=O)c2c(Cl)c(C(C)(C)C)nn2C)c1N,,CCOC(C)=O,,[H][H],,test
US20060241142A1,CC(C)(C)OC(=O)N1CCC(C#N)(c2ccc(Cl)c(Cl)c2)CC1>>N#CC1(c2ccc(Cl)c(Cl)c2)CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100137312A1,Nc1cc(Cl)ccc1-c1noc(=O)[nH]1.O=C(O)c1nc(-c2ccc(C(F)(F)F)cc2)oc1C(F)(F)F>>O=C(Nc1cc(Cl)ccc1-c1noc(=O)[nH]1)c1nc(-c2ccc(C(F)(F)F)cc2)oc1C(F)(F)F,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US06300353B1,Cc1cc(C[n+]2cnn(C[C@](O)(c3cc(F)c(F)cc3F)[C@@H](C)c3nc(-c4ccc(C#N)cc4)cs3)c2)cc(C)c1OC(=O)CN(C)C(=O)OC(C)(C)C.Cl.[Br-]>>CNCC(=O)Oc1c(C)cc(C[n+]2cnn(C[C@](O)(c3cc(F)c(F)cc3F)[C@@H](C)c3nc(-c4ccc(C#N)cc4)cs3)c2)cc1C.Cl.[Br-],,CCOC(C)=O,,,,test
US20150299152A1,Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3)s2)s1.O=S([O-])OO>>Nc1nnc(CCS(=O)(=O)CCc2nnc(NC(=O)Cc3ccccc3)s2)s1,,CC(C)=O,,O,,test
US05932571,CC(C)(C)OC(=O)N1CCCN(c2nc3ccccc3n2Cc2ccc(F)cc2)CC1.I>>Fc1ccc(Cn2c(N3CCCNCC3)nc3ccccc32)cc1.I,,CCOCC,,CCO,,test
US20040034034A1,CC1CN(C(=O)CCl)C(C)CN1Cc1ccc(F)cc1.CCOC(=O)CCCC(=O)c1cc(Cl)ccc1O>>CCOC(=O)CCCC(=O)c1cc(Cl)ccc1OCC(=O)N1C[C@H](C)N(Cc2ccc(F)cc2)C[C@H]1C,,CCC(C)=O,,[I-].[K+],,test
US20090186869A1,O=C(Oc1ccc([N+](=O)[O-])cc1)Oc1ccc([N+](=O)[O-])cc1.O[C@H]1CCOC1>>O=C(Oc1ccc([N+](=O)[O-])cc1)OC1CCOC1,,ClCCl,O,,,test
US20110142796A1,CN(C)CC(=O)Cl.Clc1ccc(N2CCNCC2)cn1>>CN(C)CC(=O)N1CCN(c2ccc(Cl)nc2)CC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,Cl,test
US05476870,CC(C)(C)OC(=O)NC(=NCCCCCCN)NC(=O)OC(C)(C)C.O=C(O)CNC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N=C(NCCCCCCNC(=O)CNC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20140228405A1,CC(=O)O.CCOC(C)=O.CN(C)C=O.CO.Cl.N[C@@H]1C[C@H]1c1ccc(NC(=O)c2ccc(-c3ccccc3)cc2)cc1.O=CC1CC1>>Cl.O=C(Nc1ccc([C@@H]2C[C@H]2N(CC2CC2)CC2CC2)cc1)c1ccc(-c2ccccc2)cc1,,CO,O,,,test
US20120141870A1,CS(=O)(=O)CCO.O=C(OC(=O)C(F)F)C(F)F>>CS(=O)(=O)CCOC(=O)C(F)F,,ClCCl,,,,test
US20140179663A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.C[C@H](NC(=O)c1nc(Br)cs1)C(F)(F)F>>C[C@H](NC(=S)c1nc(Br)cs1)C(F)(F)F,,Cc1ccccc1,,,,test
US20060052408A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC[C@]1(c2ccccc2)C[C@H]1COCc1ccccc1>>CC(C)(C)OC(=O)NCC[C@]1(c2ccccc2)C[C@H]1COCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20130172315A1,CC(C)(C)OC(=O)N1CCCC[C@@H]1C(=O)O.C[C@@H](Nc1cc(N2CCNCC2)ccc1C#N)c1ccc(Cl)cc1Cl>>C[C@@H](Nc1cc(N2CCN(C(=O)[C@H]3CCCCN3)CC2)ccc1C#N)c1ccc(Cl)cc1Cl,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080064715A1,Cc1cc(Cl)ncc1[N+](=O)[O-].c1ccc(CNCc2ccccc2)cc1>>Cc1cc(N(Cc2ccccc2)Cc2ccccc2)ncc1[N+](=O)[O-],,Cc1ccccc1,ClCCl,Cl,O=C([O-])[O-].[Na+].[Na+],test
US05616599,C1CCOC1.CCCCc1nc(C#N)c(C#N)n1C(c1ccccc1)(c1ccccc1)c1ccccc1.C[Mg]I>>CCCCc1nc(C(C)=O)c(C#N)n1C(c1ccccc1)(c1ccccc1)c1ccccc1,,C1CCOC1,,CCOCC,[Cl-].[NH4+],test
US20040092728A1,Br.Nc1ccc(C(=O)c2ccccc2)cc1>>O=C(c1ccccc1)c1ccc(Br)cc1,,CCOCC,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20110207654A1,Cc1cc(O)cc(C)c1C[C@H](N/C(=N/C(=O)OCc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@H](C)C(=O)NC[C@H](Cc1ccccc1)N/C(=N\C(=O)OCc1ccccc1)NC(=O)OCc1ccccc1>>Cc1cc(O)cc(C)c1C[C@H](NC(=N)N)C(=O)N[C@H](C)C(=O)NC[C@H](Cc1ccccc1)NC(=N)N,[Pd],CO,,Cl,,test
US20140205537A1,CC(C)Oc1cc(F)c([N+](=O)[O-])cc1F.CCOC(=O)CC(=O)OCC>>CCOC(=O)C(C(=O)OCC)c1cc(OC(C)C)c(F)cc1[N+](=O)[O-],,CS(C)=O,,O,[H-].[Na+],test
US20110046133A1,CO.O=C(O)c1ccc(CBr)c([N+](=O)[O-])c1>>COC(=O)c1ccc(CBr)c([N+](=O)[O-])c1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04788206,COc1cccc(C(=C/C=C/C(=O)Oc2ccc([N+](=O)[O-])cc2)c2cccc(OC)c2)c1.NCCCCCCc1cccnc1>>COc1cccc(C(=C/C=C/C(=O)NCCCCCCc2cccnc2)c2cccc(OC)c2)c1,,C1CCOC1,,,,test
US20140303164A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cn1nc(NS(C)(=O)=O)c2cccc(Br)c21>>Cn1nc(NS(C)(=O)=O)c2cccc(B3OC(C)(C)C(C)(C)O3)c21,,C1COCCO1,,,,test
US06689909B1,CC(=O)N1CCNCC1.CCS(=O)(=O)c1ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c(Cl)c1F>>CCS(=O)(=O)c1ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c(Cl)c1N1CCN(C(C)=O)CC1,,CN1CCCC1=O,,,,test
US20040118318A1,C=CCCCCCCCCCN.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=CCCCCCCCCCNC(=O)OC(C)(C)C,,C1CCOC1,,,,test
US20040254178A1,CC[Mg]Br.CON(C)C(=O)C1CCN(C(=O)OCc2ccccc2)CC1>>CCC(=O)C1CCN(C(=O)OCc2ccccc2)CC1,,C1CCOC1,,COC(C)(C)C,,test
US05436240,COc1cccc(C)c1[N+](=O)[O-]>>COc1ccc(C)cc1N,[Pd],,,CCO,[H][H],test
US20150291655A1,C=CC[Mg]Br.CS(=O)(=O)N1CCC(=O)CC1>>C=CCC1(O)CCN(S(C)(=O)=O)CC1,,C1CCOC1,,,,test
US20050119246A1,CC(=O)C(Cl)C(C)=O.O=C(O)c1ccccc1>>CC(=O)C(OC(=O)c1ccccc1)C(C)=O,,CN(C)C=O,,[K+].[OH-],,test
US03969351,C1COCCN1.O=[N+]([O-])c1ccc2oc(-c3sccc3CBr)nc2c1>>O=[N+]([O-])c1ccc2oc(-c3sccc3CN3CCOCC3)nc2c1,,c1ccccc1,,,,test
US20070004772A1,CC1(C)OB(c2ccncc2)OC1(C)C.Cc1cc(-c2ccc(Cl)cc2)c(Br)c2nn(Cc3ccc(C#N)cn3)c(=O)n12>>Cc1cc(-c2ccc(Cl)cc2)c(-c2ccncc2)c2nn(Cc3ccc(C#N)cn3)c(=O)n12,,C1CCOC1,,ClCCl,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20150376208A1,C=CC(=O)Cl.NC(=O)c1ccc(F)c(N)c1>>C=CC(=O)Nc1cc(C(N)=O)ccc1F,,ClCCl,O,CCN(C(C)C)C(C)C,,test
US20070112068A1,BrCCCCBr.N#CC(C#N)CCC(F)(F)F>>N#CC(C#N)(CCCCBr)CCC(F)(F)F,,CS(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100093757A1,CC(C)(C)[Si](OCCOC[C@H](Oc1ncnc2c1cnn2-c1cccc(Cl)c1Cl)C(=O)Nc1ccc(C#N)cn1)(c1ccccc1)c1ccccc1>>N#Cc1ccc(NC(=O)[C@H](COCCO)Oc2ncnc3c2cnn3-c2cccc(Cl)c2Cl)nc1,,C1CCOC1,CCOC(C)=O,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20140155391A1,C=CS(=O)(=O)Nc1cc(C(=O)OCc2ccccc2)ccc1OC.CN1CCNCC1>>COc1ccc(C(=O)OCc2ccccc2)cc1NS(=O)(=O)CCN1CCN(C)CC1,,CCO,,,,test
US20050043535A1,CCI.Cc1cc(NC(=O)NCCN2CCC(NS(=O)(=O)c3ccc(Br)cc3)CC2)c2ccccc2n1>>CCN(C1CCN(CCNC(=O)Nc2cc(C)nc3ccccc23)CC1)S(=O)(=O)c1ccc(Br)cc1,,CS(C)=O,,,,test
US20120071461A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC1CCN(c2ccncc2)CC1>>CC(C)(C)OC(=O)NCC1CCN(c2ccncc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20090176823A1,COC(=O)NCc1ccc(Cl)c(CO)c1>>COC(=O)NCc1ccc(Cl)c(C=O)c1,O=[Mn]=O,CC#N,,,,test
US20140018345A1,CS(=O)(=O)Cl.Cc1c(-c2ccnn2-c2ccc(C#N)cc2)cn2nc(N)nc2c1-c1cccc(C(F)(F)F)c1>>Cc1c(-c2ccnn2-c2ccc(C#N)cc2)cn2nc(NS(C)(=O)=O)nc2c1-c1cccc(C(F)(F)F)c1,,c1ccncc1,,O,,test
US20060093551A1,COc1cc(N(C)C(=O)OC(C)(C)C)ccc1-c1ccc2nonc2c1.FCCBr>>COc1cc(N(C)C(=O)OC(C)(C)C)ccc1Br,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080261944A1,COC(=O)c1ccc2cc[nH]c2c1.O=C1CCCCC1>>O=C(O)c1ccc2c(C3=CCCCC3)c[nH]c2c1,,CO,,O,C[O-].[Na+],test
US20100261755A1,COC(=O)c1ccnc(Cc2cc(F)c(F)c(F)c2)c1.Cl>>COC(=O)C1CCNC(Cc2cc(F)c(F)c(F)c2)C1.Cl,O=[Pt]=O,CO,,,,test
US20040210080A1,C=CC(C)=O.CCCCC1Cc2cc(N)c(F)cc2C1=O>>CCCCC1(CCC(C)=O)Cc2cc(N)c(F)cc2C1=O,,CCO,ClCCl,C[O-].[Na+],,test
US20110183985A1,CC(N=[N+]=[N-])c1ccc2ccccc2c1Br.OB(O)c1cccc(F)c1>>CC(N=[N+]=[N-])c1ccc2ccccc2c1-c1cccc(F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,O,O=C([O-])[O-].[Na+].[Na+],test
US20150166564A1,CCOC(=O)/C=C/c1ccncc1.COCCN(COC)C[Si](C)(C)C>>CCOC(=O)[C@@H]1CN(CCOC)C[C@H]1c1ccncc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030069297A1,Cc1cc(C(=O)NCCn2ccnn2)c(C=O)[nH]1.O=C1Cc2c(cccc2-c2cccc(Cl)c2)N1>>Cc1cc(C(=O)NCCn2ccnn2)c(C=C2C(=O)Nc3cccc(-c4cccc(Cl)c4)c32)[nH]1,C1CCNCC1,CCO,,,,test
US20100076014A1,O=C(c1ccccc1)c1cnc2c(cnn2-c2ccccc2)c1Cl>>OC(c1ccccc1)c1cnc2c(cnn2-c2ccccc2)c1Cl,,C1CCOC1,CCO,[BH4-].[Na+],[Cl-].[NH4+],test
US20090275592A1,CC(C)(C)OC(=O)N[C@H](CCn1cc(-c2ccc3cnccc3c2)cn1)Cc1ccc(Cl)cc1>>N[C@H](CCn1cc(-c2ccc3cnccc3c2)cn1)Cc1ccc(Cl)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020004501A1,COC(CCCN1CCN(C(=O)OC(C)(C)C)CCC1=O)OC>>CC(C)(C)OC(=O)N1CCC(=O)N(CCCC=O)CC1,,CC(=O)O,,,,test
US20140336185A1,COC(=O)C(C)(C)N.COc1ccc(CC(=O)Nc2ccc(C(=O)N(CC(=O)O)Cc3ccc(-c4noc(-c5ccc(-c6ccc(C)cc6)cc5)n4)cc3)cc2)c(C(F)(F)F)c1>>COC(=O)C(C)(C)NC(=O)CN(Cc1ccc(-c2noc(-c3ccc(-c4ccc(C)cc4)cc3)n2)cc1)C(=O)c1ccc(NC(=O)Cc2ccc(OC)cc2C(F)(F)F)cc1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20110105542A1,CN1CCC(N)CC1.COc1cc(C(=O)OOC(C)(C)C)ccc1I>>COc1cc(C(=O)NC2CCCCN2C)ccc1I,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20090036353A1,O=C(n1ccnc1)n1ccnc1.[N-]=[N+]=NCCOCCOCC(O)COCCOCCN=[N+]=[N-]>>[N-]=[N+]=NCCOCCOCC(COCCOCCN=[N+]=[N-])OC(=O)n1ccnc1,,ClCCl,,,,test
US20150065468A1,Brc1cnc2[nH]ccc2c1.CC1(C)OB(c2ccc(CC(=O)O)c(F)c2)OC1(C)C>>O=C(O)Cc1ccc(-c2cnc3[nH]ccc3c2)cc1F,,O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20110034463A1,N.N#Cc1ccc(C(=O)Cl)nc1SCc1ccc(Cl)cc1>>N#Cc1ccc(C(N)=O)nc1SCc1ccc(Cl)cc1,,ClCCl,,Cl,,test
US20040132727A1,COc1cc2nccc(Oc3cc(C)c(N)cc3C)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OCc1ccc(F)cc1>>COc1cc2nccc(Oc3cc(C)c(NC(=O)OCc4ccc(F)cc4)cc3C)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US06403608B1,C1CCOC1.CCC#N.O.[Li]C(C)CC>>CCc1cc2ccccc2c(=O)[nH]1,,C1CCOC1,,,,test
US20050143452A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=[N+]([O-])c1cccc2c1OC(CO)C2>>Cc1ccc(S(=O)(=O)OCC2Cc3cccc([N+](=O)[O-])c3O2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070078120A1,COc1cccc(C2(COS(C)(=O)=O)CCN(c3ccccc3OC)CC2)c1.Oc1ccccc1>>COc1cccc(C2(COc3ccccc3)CCN(c3ccccc3OC)CC2)c1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20140343050A1,CC(C)(C)OC(=O)N[C@H](CCC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)O)C(=O)OCCC(F)(F)F>>N[C@H](CCC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)O)C(=O)OCCC(F)(F)F,,CCOCC,,Cl,,test
US20160235886A1,C=CC(=O)Cl.OCCc1ccc(Oc2cccc(Oc3ccc(Oc4ccccc4)cc3)c2)cc1>>C=CC(=O)OCCc1ccc(Oc2cccc(Oc3ccc(Oc4ccccc4)cc3)c2)cc1,,ClCCl,,CCN(CC)CC,,test
US20100016368A1,CCOC(=O)Cn1ncc2c1CCCC2NS(=O)(=O)c1cc(C#C[Si](C)(C)C)cc(C(F)(F)F)c1>>C#Cc1cc(C(F)(F)F)cc(S(=O)(=O)NC2CCCc3c2cnn3CC(=O)OCC)c1,,CN(C)C=O,O,[F-].[K+],,test
US20030139460A1,C1=COCCC1.C[C@@H](O)CO>>C[C@@H](O)COC1CCCCO1,,ClCCl,,CCN(CC)CC,,test
US20110039829A1,CC(C)(C)OC(=O)NC1(C(=O)OCc2ccccc2)CCC1>>NC1(C(=O)OCc2ccccc2)CCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060111426A1,CC(=O)O.CC1(CC(=O)O)Nc2cccc([N+](=O)[O-])c2C1S(=O)(=O)c1ccc(Cl)cc1.COC(=O)Cn1c(C)c(S(=O)(=O)c2ccc(Cl)cc2)c2c(C#N)c(Cl)ccc21>>CCOC(=O)Cn1c(C)c(S(=O)(=O)c2ccc(Cl)cc2)c2c(N)cccc21,[Pt],,,,,test
US04963543,O=C(S[C@H]1C[C@@H](CSC(F)F)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1)c1ccccc1>>O=C(OCc1ccc([N+](=O)[O-])cc1)N1C[C@@H](S)C[C@H]1CSC(F)F,,C1CCOC1,CO,CC(=O)O,C[O-].[Na+],test
US20100113436A1,C1COCCN1.O=C1CCC2(CC1)OOC1(CCCCC1)OO2>>C1CCC2(CC1)OOC1(CCC(N3CCOCC3)CC1)OO2,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070208054A1,CCN(CC)CC.CCc1cc(Br)ccc1CCO>>CCc1cc(Br)ccc1CCNC,,ClCCl,,,,test
US20100015141A1,CN(C(=O)Nc1cccnc1)c1cccc([N+](=O)[O-])c1>>Nc1cccc(NC(=O)Nc2cccnc2)c1,[Pd],CO,,,,test
US20080275038A1,Nc1cc(-c2ccncc2F)c(-c2cccnc2)nc1N.S=C=Nc1ccc(Cl)cc1>>Fc1cnccc1-c1cc2nc(Nc3ccc(Cl)cc3)[nH]c2nc1-c1cccnc1,,CCO,,CC(C)N=C=NC(C)C,,test
US20060188938A1,CCOC(=O)CC(C)=O.COC(=O)/C=C(/C)N.O=Cc1ccccc1Cl>>CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1ccccc1Cl,,CCO,CCOC(C)=O,CC(=O)O,,test
US20120130129A1,C1CCOC1.CC(C)(C)[O-].COc1cccc(C=O)c1.O=C(O)CCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>CCC=CC(=O)O.COc1cccc(C=CCCC(=O)O)c1,,C1CCOC1,,[Br-].[K+],,test
US20080039437A1,C=CCN(C(=O)C1CCN(c2[nH]c(=O)c(C(=O)OCC)cc2C#N)CC1)S(=O)(=O)Cc1ccccc1.O=C(O)C(F)(F)S(=O)(=O)F>>C=CCN(C(=O)C1CCN(c2nc(OC(F)F)c(C(=O)OCC)cc2C#N)CC1)S(=O)(=O)Cc1ccccc1,,CC#N,,,,test
US20120295884A1,COC(=O)Cn1nc(C(C)=O)c2cc(OCc3ncccn3)ccc21>>CC(=O)c1nn(CC(=O)O)c2ccc(OCc3ncccn3)cc12,,C1CCOC1,O,[Li]O,,test
US04910282,O=C(O)c1cccc(O)c1.O=C(c1ccc(F)cc1)c1ccc(F)cc1>>O=C(O)c1cccc(Oc2ccc(C(=O)c3ccc(F)cc3)cc2)c1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040209865A1,Cn1cnc2cc(CN3CCCC3)ccc21.O=C1CCC(=O)N1I>>Cn1c(I)nc2cc(CN3CCCC3)ccc21,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20130177590A1,CC(C)(C)NC(=O)NCc1nonc1C(=NO)Nc1ccc(F)c(Cl)c1.O=C(O)C(F)(F)F>>NC(=O)NCc1nonc1C(=NO)Nc1ccc(F)c(Cl)c1.O=C(O)C(F)(F)F,,O=C(O)C(F)(F)F,,,,test
US20030092676A1,OCc1ccc2ccccc2n1>>OCC1CCc2ccccc2N1,[Pt],C1CCOC1,CCO,,,test
US08835456B1,CC(C)(C)OC(=O)N1C2CCCCC2C[C@H]1c1nc(-c2ccc(-c3ccc(-c4c[nH]c([C@@H]5C6CCC(C6)N5C(=O)OC(C)(C)C)n4)cc3)cc2)c[nH]1>>c1cc(-c2c[nH]c([C@@H]3CC4CCCCC4N3)n2)ccc1-c1ccc(-c2c[nH]c([C@H]3NC4CCC3C4)n2)cc1,,CO,,O,,test
US05185351,CCCCc1nc(I)c(C=O)n1Cc1ccc(C(=O)OC)c(Cl)c1Cl>>CCCCc1ncc(C=O)n1Cc1ccc(C(=O)OC)c(Cl)c1Cl,[Pd],CCOC(C)=O,O,,,test
US20150225379A1,CC(C)(C)OC(=O)N1CCC(CN[C@@H]2C[C@H]2c2ccccc2)(Cc2ccc(CC#N)cc2)CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCC(Cc2ccc(CC#N)cc2)(CN(C(=O)C(F)(F)F)[C@@H]2C[C@H]2c2ccccc2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05610303,Cc1ncnc(Nc2ccc(C(=O)/C=C/C3CCN(Cc4ccccc4)CC3)cc2)c1C>>Cc1ncnc(Nc2ccc(C(=O)CCC3CCN(Cc4ccccc4)CC3)cc2)c1C,O=[Pt],C1COCCO1,,CCO,[H][H],test
US20050049239A1,C1CCOC1.CC(C)(C)OC(=O)NCCO.CC(C)Oc1ccccc1O.CC(C)Oc1ccccc1OCCNC(=O)OC(C)(C)C>>CC(C)Oc1ccccc1OCCNCc1cccc(C(=O)N2CCCCC2)c1,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160244437A1,Cc1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)cc1-c1cccc(C(=O)NCCOCCOCCO)c1.Cl>>Cc1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)cc1-c1cccc(C(=O)NCCOCCOCCO)c1.Cl,,C1COCCO1,,CC#N,,test
US05994368,CCI.Cc1cc(C(=O)O)c2cccc(OCc3ccccc3)c2n1>>CCOC(=O)c1cc(C)nc2c(OCc3ccccc3)cccc12,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20090105499A1,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C/C=C/C(=O)OCC>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C/C=C/CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],[Cl-].[NH4+],test
US05650410,C1COCCN1.CCOC(=O)c1c(CCl)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC(C)C)c1>>CCOC(=O)c1c(CN2CCOCC2)nc2cc(OC)c(OC)cc2c1-c1ccc(OC)c(OC(C)C)c1,,ClCCl,,CCO,,test
US20110046093A1,CN1CCN(N)CC1.COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC1(CCC1)C(=O)N2C>>COc1cc(C(=O)NN2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC1(CCC1)C(=O)N2C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US06194410B1,CSc1nn2c(Cl)cc(C)nc2c1S(=O)(=O)c1ccccc1.c1ccc(N2CCNCC2)cc1>>CSc1nn2c(N3CCN(c4ccccc4)CC3)cc(C)nc2c1S(=O)(=O)c1ccccc1,,CN(C)C=O,,,,test
US20120270875A1,CC(=O)OC(C)=O.COC(=O)[C@H](CN)NC(=O)c1c(C)nc(NCCCc2cccc3[nH]ncc23)nc1C>>CC(=O)NC[C@H](NC(=O)c1c(C)nc(NCCCc2cccc3[nH]ncc23)nc1C)C(=O)O,,CN(C)C=O,,CCN(CC)CC,,test
US20160046666A1,C(=NC1CCCCC1)=NC1CCCCC1.C1CCOC1.C=CCCCCCCCCC(=O)O.CN(C)c1cccc2c(C(=O)C(C)(C)C)c3c(cc12)CC(CO)(CO)C3.CN(C)c1ccncc1>>C=CCCCCCCCCC(=O)OCC1(COC(=O)CCCCCCCCC=C)Cc2cc3c(N(C)C)cccc3c(C(=O)C(C)(C)C)c2C1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20060194801A1,COC(=O)c1ccc(/C=C/C(F)(F)F)cc1OC>>COc1cc(/C=C/C(F)(F)F)ccc1C(=O)O,,CO,,[Na+].[OH-],,test
US20090312327A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCN[C@@H]1CN(Cc2ccccc2)C[C@H]1c1ccc(Cl)c(Cl)c1>>CCN(C(=O)OC(C)(C)C)[C@@H]1CN(Cc2ccccc2)C[C@H]1c1ccc(Cl)c(Cl)c1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20150038528A1,CC(C)(C)OC(=O)C(CN)C1CC1.CCOC(=O)c1nc(C#N)c2cc(Oc3cccnc3)ccc2c1O>>CC(C)(C)OC(=O)C(CNC(=O)c1ncc2c(c1O)=CCC(C#N)(Oc1cccnc1)C=2)C1CC1,,CC(=O)N(C)C,,C1CCC2=NCCCN2CC1,,test
US06194426B1,CC(=O)c1c(Cl)c(-c2cccnc2)n2c1C=C(Cl)CC2>>CC(=O)c1c(Cl)c(-c2cccnc2)n2c1CCCC2,[Pd],,,,,test
US20130090342A1,Cc1cc(N)ccc1Br.O=[N+]([O-])c1ccccc1F>>Cc1cc(Nc2ccccc2[N+](=O)[O-])ccc1Br,,O,,CCN(CC)CC,Cl,test
US20120046267A1,BrBr.N#Cc1cc(F)c(N)cc1F>>N#Cc1cc(F)c(N)c(Br)c1F,,CC(=O)O,,O,,test
US20040077669A1,Clc1cc(Cl)ncn1.Nc1cccc(F)c1F>>Fc1cccc(Nc2cc(Cl)ncn2)c1F,,CCO,,,,test
US20110118236A1,CCOC(=O)Cn1nc(C(F)(F)F)c2c1CCN(C(=O)OC(C)(C)C)C2>>CC(C)(C)OC(=O)N1CCc2c(c(C(F)(F)F)nn2CC(=O)O)C1,,CCO,,[Na+].[OH-],,test
US20140155389A1,COc1cc(C(=O)O)ccc1[N+](=O)[O-]>>COc1cc(CO)ccc1[N+](=O)[O-],,C1CCOC1,O,[BH4-].[Na+],,test
US20130143863A1,CC1(C)c2ccc(F)cc2C(=O)N1c1cncc(CO)c1.O=S(Cl)Cl>>CC1(C)c2ccc(F)cc2C(=O)N1c1cncc(CCl)c1,,ClCCl,,,,test
US20070078184A1,CC(=O)Cl.CC(=O)c1ccc(-c2c(C)cc(OCCO)cc2C)cc1>>CC(=O)OCCOc1cc(C)c(-c2ccc(C(C)=O)cc2)c(C)c1,,CCOC(C)=O,ClCCl,CCN(CC)CC,O,test
US20040209933A1,Cc1ccc(S(=O)(=O)O)cc1.FC(F)(F)Oc1ccc(C=Cc2nc(COc3ccc(CCCCn4ccnn4)cc3)co2)cc1>>Cc1ccc(S(=O)(=O)[O-])cc1.FC(F)(F)Oc1ccc(C=Cc2nc(COc3ccc(CCCC[NH+]4C=CN=N4)cc3)co2)cc1,,CCO,,,,test
US20020103229A1,O=C(Nc1cccc(-c2nn(C3CCCCO3)c3ccc(-c4ncn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc23)c1)c1ccco1>>O=C(Nc1cccc(-c2n[nH]c3ccc(-c4nc[nH]n4)cc23)c1)c1ccco1,,C1COCCO1,Cl,,,test
US20110085985A1,CN(C)c1ccc(C(=O)O)cc1.Nc1ccc(F)nc1F>>CN(C)c1ccc(-c2nc3ccc(F)nc3o2)cc1,,ClCCl,c1ccncc1,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20070208018A1,CNC=O.COC(=O)c1cn(-c2cc3c(=O)n(NS(C)(=O)=O)c(=O)[nH]c3cc2C(F)(F)F)cn1>>CNC(=O)c1cn(-c2cc3c(=O)n(NS(C)(=O)=O)c(=O)[nH]c3cc2C(F)(F)F)cn1,,CN(C)C=O,,C[O-].[Na+],,test
US20070155805A1,CNOC.Cc1ccc2c(C)c(C(=O)O)oc2c1>>CON(C)C(=O)c1oc2cc(C)ccc2c1C,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US06472386B1,COc1cc(-c2nc(CCO)cs2)cc(OC)c1OC.CS(=O)(=O)Cl>>COc1cc(-c2nc(CCOS(C)(=O)=O)cs2)cc(OC)c1OC,,CCOC(C)=O,c1ccncc1,,,test
US20120316188A1,COc1ccc(Cn2cc(-c3nc(Nc4ccccn4)cs3)cn2)cc1>>c1ccc(Nc2csc(-c3cn[nH]c3)n2)nc1,,O=C(O)C(F)(F)F,,[Na+].[OH-],,test
US20090105219A1,CN(C)CN(C)C.O=[N+]([O-])c1cccc2[nH]ccc12>>CN(C)Cc1c[nH]c2cccc([N+](=O)[O-])c12,,CC(=O)O,,[Na+].[OH-],,test
US20080255122A1,CC(=O)c1cc2cc([N+](=O)[O-])ccc2o1>>CC(=O)c1cc2cc(N)ccc2o1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20070161686A1,CI.CN(C)C=O.Cc1onc(-c2ccccc2)c1-c1nnc(-c2ccc3[nH]c(=O)[nH]c3c2)o1>>Cc1onc(-c2ccccc2)c1-c1nnc(-c2ccc3c(c2)n(C)c(=O)n3C)o1,,CCOC(C)=O,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20130035342A1,C1CNCCN1.O=C(O)C1(Br)NC=CS1>>O=C(O)c1cnc(N2CCNCC2)s1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20140256719A1,CC(C)(C)N.CCOC(C)=O.FC(F)c1ncc(Br)cc1SCc1ccccc1.O>>CC(C)(C)NS(=O)(=O)c1cc(Br)cnc1C(F)F,,ClC(Cl)(Cl)Cl,,,,test
US05374641,CCOC(=O)Cl.COCOc1ccc(C(CNS(=O)(=O)c2ccc(Cl)cc2)Cc2cccnc2)cc1>>CCOC(=O)N(CC(Cc1cccnc1)c1ccc(OCOC)cc1)S(=O)(=O)c1ccc(Cl)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20130096118A1,COCCOc1ccc2c(c1)[nH]c1c(C(N)=O)ncc(-c3cccc(N)c3C)c12.Clc1ncnc2ccccc12>>COCCOc1ccc2c(c1)[nH]c1c(C(N)=O)ncc(-c3cccc(Nc4ncnc5ccccc45)c3C)c12,,CC(C)O,CCOC(C)=O,,,test
US20040048858A1,CC(=O)c1ccc(C(=O)O)cc1.COc1cc(OC)c(-c2cc3ccccc3s2)cc1C=O>>COc1cc(OC)c(-c2cc3ccccc3s2)cc1/C=C/C(=O)c1ccc(C(=O)O)cc1,,CN(C)C=O,O,[Na+].[OH-],,test
US20090264445A1,CC1(C)OC[C@@H](Cn2ccc(N)n2)O1.COc1ccc(F)c(OC2=CC(=O)N([C@@H](CC(C)C)C(=O)O)C2)c1F>>COc1ccc(F)c(OC2=CC(=O)N([C@@H](CC(C)C)C(=O)Nc3ccn(C[C@@H]4COC(C)(C)O4)n3)C2)c1F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20130005716A1,CC(=O)O[C@H](C(=O)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(O)c1)c1ccccc1.CI>>COc1cc([C@H](Cc2c(Cl)c[n+]([O-])cc2Cl)OC(=O)[C@@H](OC(C)=O)c2ccccc2)ccc1OC(F)F,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20050261327A1,Cc1ccnc(NCC2CCC3(CC2)CN(C(=O)OC(C)(C)C)c2ccccc23)c1[N+](=O)[O-]>>Cc1ccnc(NCC2CCC3(CC2)CN(C(=O)OC(C)(C)C)c2ccccc23)c1N,[Pd],CCO,CCOC(C)=O,,,test
US20050215556A1,C=CCBr.CC(C)(C)[Si](Oc1ccc(O)c(N2C(=O)c3ccccc3C2=O)c1)(c1ccccc1)c1ccccc1>>C=CCOc1ccc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1N1C(=O)c2ccccc2C1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150051189A1,COC(=O)C1CC2(CCN1)OCCO2.O=COc1ccc([N+](=O)[O-])cc1>>COC(=O)C1CC2(CCN1C=O)OCCO2,,CCOC(C)=O,ClCCl,,,test
US20040210066A1,Cc1cc(C)c(C)c(O)c1.Cc1ccccc1C(=O)C(C)(C)Br>>Cc1ccc(C(=O)C(C)(C)Oc2cc(C)cc(C)c2C)cc1,,CS(C)=O,O,CO,O=C([O-])[O-].[K+].[K+],test
US20100261698A1,Cc1ccc(C(=O)n2c(-c3cccnc3)cc3cc(C#N)ccc32)cc1C(=O)OC(C)(C)C>>Cc1ccc(C(=O)n2c(-c3cccnc3)cc3cc(C#N)ccc32)cc1C(=O)O,,O=C(O)C(F)(F)F,,,,test
US20030144263A1,NNCCO.O=C1CCN(c2ccc(N3C[C@H](COc4ccon4)OC3=O)cc2F)CC1>>O=C1O[C@@H](COc2ccon2)CN1c1ccc(N2CCC(=NNCCO)CC2)c(F)c1,,CO,ClCCl,,,test
US20100105744A1,CSCc1cccc2c(C(CCC#N)c3ccc(Cl)c(F)c3)c[nH]c12.O=C(OO)c1cccc(Cl)c1>>CS(=O)Cc1cccc2c(C(CCC#N)c3ccc(Cl)c(F)c3)c[nH]c12,,CO,,ClCCl,,test
US20100216746A1,Cc1nc(Cl)c(C(=O)NCc2ccc(Cl)c(Oc3cc(C#N)cc(C=O)c3)c2F)[nH]1>>Cc1nc(Cl)c(C(=O)NCc2ccc(Cl)c(Oc3cc(C#N)cc(CO)c3)c2F)[nH]1,,CCOC(C)=O,CO,[BH4-].[Na+],,test
US20090023720A1,CC(C)(CNc1c([N+](=O)[O-])c(Cl)nc2ccccc12)NS(C)(=O)=O>>CC(C)(CNc1c(N)c(Cl)nc2ccccc12)NS(C)(=O)=O,[Pt],CC#N,,,,test
US20060217382A1,COc1ccc(Nc2ncc(C(C)NC(=O)c3ccco3)nn2)cc1>>COc1ccc(Nc2ncc3c(C)nc(-c4ccco4)n3n2)cc1,,ClCCCl,,O=P(Cl)(Cl)Cl,,test
US04025630,COc1cc(OC)cc(C(C)CCCc2ccc(F)cc2)c1>>CC(CCCc1ccc(F)cc1)c1cc(O)cc(O)c1,,O,,Br,CC(=O)O,test
US05688815,CN(C)CCn1ccc(=O)c(OCc2ccccc2)c1C(O)c1ccccc1>>CN(C)CCn1ccc(=O)c(O)c1C(O)c1ccccc1,,CCO,ClCCl,,,test
US04496566,CCOC(=O)c1c[nH]c2nc(N3CCN(C(C)=O)CC3)c(F)cc2c1=O.Cc1ccc(S(=O)(=O)OCCF)cc1>>CCOC(=O)c1cn(CCF)c2nc(N3CCN(C(C)=O)CC3)c(F)cc2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070054911A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1CCC(Nc2ccc(F)cc2)CC1>>CC(=O)N(c1ccc(F)cc1)C1CCN(C(=O)OC(C)(C)C)CC1,CN(C)c1ccncc1,ClCCl,,,,test
US20030187001A1,COc1cc(-c2cn(C3CCCC3)c3ncnc(N)c23)ccc1N.O=C(Cl)OCc1ccccc1>>COc1cc(-c2cn(C3CCCC3)c3ncnc(N)c23)ccc1NC(=O)OCc1ccccc1,,O,,ClCCl,c1ccncc1,test
US06509344B1,CCCN.O=C1c2ccccc2-c2oc(=O)c3ccccc3c21>>CCCn1c2c(c3ccccc3c1=O)C(=O)c1ccccc1-2,,ClC(Cl)Cl,,,,test
US20090062251A1,CC(C)(C)OC(=O)N[C@H]1CCNC1.Cn1c2c(c3cc(C(=O)O)ccc31)CC(C1CCOCC1)CC2>>Cn1c2c(c3cc(C(=O)N4CC[C@H](NC(=O)OC(C)(C)C)C4)ccc31)CC(C1CCOCC1)CC2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080076758A1,CN(CC1CCCN1)S(C)(=O)=O.Clc1nc(N2CCOCC2)c2sc(CBr)cc2n1>>CN(CC1CCCN1Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1)S(C)(=O)=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060089367A1,NCCc1cccc(C(F)(F)F)c1.O=C(O)c1ccc2c(c1)nc(COc1ccccc1)n2Cc1ccc(OC(F)(F)F)cc1>>O=C(NCCc1cccc(C(F)(F)F)c1)c1ccc2c(c1)nc(COc1ccccc1)n2Cc1ccc(OC(F)(F)F)cc1,,C1CCOC1,,CC(C)N=C=NC(C)C,,test
US20030153568A1,CCN=C=O.Nc1nc2ccc(Cc3ccccc3)cc2s1>>CCNC(=O)Nc1nc2ccc(Cc3ccccc3)cc2s1,,Cc1ccccc1,,CCN(CC)CC,,test
US20100063067A1,CCOC(=O)C1CCN(c2ccc(Cl)c(OC)c2)CC1.O=C1CCC(=O)N1Cl>>CCOC(=O)C1CCN(c2cc(OC)c(Cl)cc2Cl)CC1,,CCOCC,O,CC(=O)O,Cl,test
US20050143581A1,CCOC(=O)c1csc(N)n1.O=C(Cl)Cl>>CCOC(=O)c1csc(N=C=O)n1,CN(C)C=O,Clc1ccccc1,,,,test
US20120015907A1,CCN(c1nc2oc(-c3ccc(F)cc3)c(C(=O)NC)c2cc1CCCC(=O)O)S(C)(=O)=O.COC(=O)[C@@H]1CCCN1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2nc(N(C)S(C)(=O)=O)c(CCCC(=O)N3CCC[C@H]3C(=O)OC)cc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050154045A1,CCN=C=O.O=C(Nc1ccc(-c2ccc(CO)cc2)cc1)[C@H]1CN2CCC1CC2>>CCNC(=O)OCc1ccc(-c2ccc(NC(=O)[C@H]3CN4CCC3CC4)cc2)cc1,,C1CCOC1,CN(C)C=O,,,test
US20060173018A1,CC(C)(C)OC(=O)N1CC[C@H](CN)C1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)N1CC[C@H](CNC(=O)OCc2ccccc2)C1,,C1CCOC1,,CCN(CC)CC,,test
US06358971B1,CON(C)C(=O)c1ccc2nc(NC(=O)C(F)(F)F)c(-c3ccccc3)n2c1.Fc1cccc(Br)c1F>>O=C(c1ccc2nc(NC(=O)C(F)(F)F)c(-c3ccccc3)n2c1)c1cccc(F)c1F,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US06369077B1,CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)O.NC1CCN(Cc2ccccc2)CC1>>CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NC1CCN(Cc2ccccc2)CC1,,ClC(Cl)Cl,ClCCl,ClCCCl,On1nnc2ccccc21,test
US20130331378A1,C=C(C)c1ccc2c(Cc3cccc(C(=O)OC)n3)c(-c3ccccc3)nn2c1>>C=C(C)c1ccc2c(Cc3cccc(C(=O)O)n3)c(-c3ccccc3)nn2c1,,CO,,Cl,[K+].[OH-],test
USRE039591E1,O=C1c2ccccc2C(=O)N1O.OCc1cccc2ccccc12>>O=C1c2ccccc2C(=O)N1OCc1cccc2ccccc12,,C1CCOC1,CCOCC,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100234395A1,CNO.COc1ccc(-c2nc(C3(C)CCNCC3)oc2-c2ccc(OC)cc2)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc(-c2nc(C3(C)CCN(C(=O)N(C)O)CC3)oc2-c2ccc(OC)cc2)cc1,,C1CCOC1,,CCN(CC)CC,Cl,test
US20120289522A1,CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CNC(=O)OCc4ccccc4)cc3)cc2)CC1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CN)cc3)cc2)CC1,,O=C(O)C(F)(F)F,,,,test
US20080114022A1,COC(=O)Cc1c(C)[nH]c2nc(Cl)ccc12.CS(=O)(=O)c1ccc(CBr)cc1>>Cc1c(CC(=O)O)c2ccc(Cl)nc2n1Cc1ccc(S(C)(=O)=O)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20070032485A1,CCOC(=O)N1c2ccc(OC)nc2[C@@H](Nc2ncc(O)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC.CI>>CCOC(=O)N1c2ccc(OC)nc2[C@@H](Nc2ncc(OC)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC,,CN(C)C=O,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20140221344A1,ClCc1ccc(Cl)nn1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCc1ccc(Cl)nn1,,CN(C)C=O,,O,,test
US20100190688A1,CC(C(=O)NC1CCCC2CCC(C(=O)NC3CCCc4ccccc43)N2C1=O)N(C)C(=O)OC(C)(C)C>>CNC(C)C(=O)NC1CCCC2CCC(C(=O)NC3CCCc4ccccc43)N2C1=O,,C1COCCO1,CCOC(C)=O,Cl,,test
US05280032,C1=COCCC1.OC1CCc2cc(Br)ccc21>>Brc1ccc2c(c1)CCC2OC1CCCCO1,,ClCCl,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20100113462A1,CCOC(=O)C1(NC(=O)C2CC3CCC2C3)Cc2ccccc2C1>>O=C(NC1(C(=O)O)Cc2ccccc2C1)C1CC2CCC1C2,,CCO,,O,[K+].[OH-],test
US20090054435A1,CC(C)[Si](OS(=O)(=O)C(F)(F)F)(C(C)C)C(C)C.Oc1ccc(Br)cc1>>CC(C)[Si](Oc1ccc(Br)cc1)(C(C)C)C(C)C,,ClCCl,,Cc1cccc(C)n1,,test
US20140018319A1,COc1ccc(CN(c2nc(S(C)(=O)=O)nn3c(C#N)cnc23)C2CC2)cc1.N#Cc1cc(N)c(Cl)c(N2CCOC(C(=O)N3CCOCC3)C2)c1>>N#Cc1cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c(Cl)c(N2CCOC(C(=O)N3CCOCC3)C2)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],O=C([O-])O.[Na+],test
US20140363452A1,CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)O)OC)N(C)C(=O)[C@@H](NC(=O)C(C)(C)NC(=O)OCC1c2ccccc2-c2ccccc21)C(C)C.C[C@H]1NC(=O)N[C@H]1CCCCCC(=O)NCCNC(=O)[C@@H](N)Cc1ccccc1>>CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCNC(=O)CCCCC[C@@H]1NC(=O)N[C@@H]1C)OC)N(C)C(=O)[C@@H](NC(=O)C(C)(C)NC(=O)OCC1c2ccccc2-c2ccccc21)C(C)C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130217666A1,COC(CN)OC.Fc1cc2c(cc1Br)C(Cl)=NC1CC2C1>>COC(CNC1=NC2CC(C2)c2cc(F)c(Br)cc21)OC,,CCCCO,O,,,test
US06180630B2,CCOC(=O)c1nnc2c(c1Cl)CCCC2.NNc1ccc(F)cc1>>O=c1c2n[nH]c3c(c-2nn1-c1ccc(F)cc1)CCCC3,,Cc1ccccc1C,,Cl,,test
US07713963B2,Cc1cccc2c1CC(N)C2.O=C(Cl)c1ccc(F)cc1>>Cc1cccc2c1CC(NC(=O)c1ccc(F)cc1)C2,,C1COCCO1,,CCN(CC)CC,,test
US04727067,c1ccc(COCCOc2ccccc2-c2ccc(COCc3ccc(-c4ccccc4OCCOCc4ccccc4)cc3)cc2)cc1>>OCCOc1ccc(O)cc1,[Pd],,,C1CCOC1,,test
US04753941,CCOC(=O)Nc1cccc(C(=O)O)c1.COc1ccc2ccc(N)nc2n1>>CCOC(=O)Nc1cccc(C(=O)Nc2ccc3ccc(OC)nc3n2)c1,,O,,,,test
US20090274655A1,COC(=O)c1sc(-c2ccc(N)cc2)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C(C)C.O=C(O)c1cnco1>>COC(=O)c1sc(-c2ccc(NC(=O)c3cnco3)cc2)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C(C)C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05470947,O=C(O)c1cccnc1.O=[N+]([O-])c1ccc(O)cc1>>O=C(Oc1ccc([N+](=O)[O-])cc1)c1cccnc1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20020183516A1,CC(C)(C)[Si](C)(C)Cl.OCc1ccccc1I>>CC(C)(C)[Si](C)(C)OCc1ccccc1I,,CN(C)C=O,,O,c1c[nH]cn1,test
US20050277647A1,C[C@@H](Br)C(=O)O.FC(F)(F)c1ccc(N2CCNCC2)nc1>>C[C@@H](C(=O)O)N1CCN(c2ccc(C(F)(F)F)cn2)CC1,,ClCCl,,,,test
US20080051458A1,CC(C)C(OC(=O)ON1C(=O)CCC1=O)OC(=O)c1ccccc1.NC1(C(=O)O)CC1>>CC(C)C(OC(=O)NC1(C(=O)O)CC1)OC(=O)c1ccccc1,,CC#N,O,,,test
US20040006082A1,CN(C)C=CC(=O)c1ccco1.N#CCC(N)=O>>N#Cc1ccc(-c2ccco2)[nH]c1=O,,CS(C)=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US04946839,O=C(OCc1ccccc1)[C@@H]1C[C@H](C(=O)OCc2ccccc2)N1Cc1ccccc1>>O=C(O)[C@@H]1C[C@H](C(=O)O)N1,[Pd],CO,O,,,test
US20050256113A1,CC(=O)O.CCOC(=O)C[N+](=O)[O-].CCOC([O-])[O-].Cc1ccc(C(=O)O)cc1N>>CCOC(=O)c1cn(-c2cc(C(=O)O)ccc2C)cn1,[Fe],,,,,test
US20080045566A1,COc1cc2cc[nH]c(=O)c2cc1C.O=P(Cl)(Cl)Cl>>COc1cc2ccnc(Cl)c2cc1C,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20140213586A1,CNC.COc1cccc(N(C(=O)CCl)C(C(=O)c2c[nH]c3ccccc23)c2ccccc2)c1>>COc1cccc(N(C(=O)CN(C)C)C(C(=O)c2c[nH]c3ccccc23)c2ccccc2)c1,,C1CCOC1,,,,test
US04062966,ClCc1cscn1.OC(Cn1ccnc1)c1ccc(Cl)cc1Cl>>Cl.Clc1ccc(C(Cn2ccnc2)OCc2cscn2)c(Cl)c1,,C1CCOC1,O,[H-].[Na+],,test
US20090062268A1,C=O.NC(=O)c1cccc2[nH]c(C34CCC(CC3)CN4)nc12>>CN1CC2CCC1(c1nc3c(C(N)=O)cccc3[nH]1)CC2,,CO,,[BH3-]C#N.[Na+],,test
US20080167360A1,CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(F)cc2)CC(C)(C)C1.OCCOCCCl>>CC1(C)CC(=C(c2ccc(F)cc2)c2ccc(OCCOCCO)cc2)CC(C)(C)C1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030178607A1,CCCCCCCCCCOc1cc2c3cc(OCCCCCCCCCC)c(OCCCCCCCCCC)cc3c3c(OC)ccc(OC)c3c2cc1OCCCCCCCCCC>>CCCCCCCCCCOc1cc2c3c(c4cc(OCCCCCCCCCC)c(OCCCCCCCCCC)cc4c2cc1OCCCCCCCCCC)C(=O)C=CC3=O,,CCOCC,,C1CCOC1,,test
US05039673,CS(=O)[O-].OB(O)c1ccccc1CBr>>CS(=O)(=O)Cc1ccccc1B(O)O,,CN(C)C=O,,Cl,,test
US05039706,CCCCCCCCCCCCc1ccc(N)cc1.O=C(CCCl)c1ccc(F)cc1>>CCCCCCCCCCCCc1ccc(NCCC(=O)c2ccc(F)cc2)cc1.Cl,,CCOCC,,CCN(CC)CC,,test
US20070191373A1,CC1CCC(O)C1.CS(=O)(=O)Cl>>CC1CCC(OS(C)(=O)=O)C1,,ClCCl,,CCN(CC)CC,,test
US04997841,CNS(=O)(=O)/C=C/c1ccc2[nH]cc(C3CCN(C)CC3)c2c1>>CNS(=O)(=O)CCc1ccc2[nH]cc(C3CCN(C)CC3)c2c1,[Pd],CN(C)C=O,,Cl,[H][H],test
US20160184318A1,CC(C)c1noc(C2CCCNC2)n1.Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)O)n1>>Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)N2CCCC(c3nc(C(C)C)no3)C2)n1,,CN(C)C=O,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20040044012A1,CCNc1nc(SC)ncc1C=O.COc1cc(N)cc(OC)c1>>CCNc1nc(SC)ncc1CNc1cc(OC)cc(OC)c1,,CC(=O)O,,,,test
US20090281080A1,CI.Cc1ccc(S(=O)(=O)n2c(=O)n3c4c(cccc42)NC(=O)C3)cc1>>Cc1ccc(S(=O)(=O)N2CN3CCN(C)c4cccc2c43)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070281955A1,COc1cc(-c2nc3sccn3c2-c2ccnc(NC3CCNCC3)n2)ccc1F.O=S(=O)(Cl)C1CC1>>COc1cc(-c2nc3sccn3c2-c2ccnc(NC3CCN(S(=O)(=O)C4CC4)CC3)n2)ccc1F,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20030120071A1,COC(=O)[C@H](C)N.O=P(Cl)(Cl)Oc1ccccc1>>CN[C@@H](C)C(=O)OP(=O)(Cl)Oc1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
US20050153959A1,Cc1cc(CC(=O)c2cccc(Br)n2)cc2cn(COCC[Si](C)(C)C)nc12>>Cc1cc(CC(O)c2cccc(Br)n2)cc2cn(COCC[Si](C)(C)C)nc12,,CO,,[BH4-].[Na+],,test
US06194406B1,COc1cc(C(=O)N2CCC(CCOS(C)(=O)=O)(c3ccccc3)C2)cc(OC)c1OC.OCc1ccc(Cn2c(N3CCCNCC3)nc3ccccc32)o1>>COc1cc(C(=O)N2CCC(CCN3CCCN(c4nc5ccccc5n4Cc4ccc(CO)o4)CC3)(c3ccccc3)C2)cc(OC)c1OC,,CO,,,,test
US20130085132A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.FC(F)(F)COCc1cccc(Br)c1>>CC1(C)OB(c2cccc(COCC(F)(F)F)c2)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20060223849A1,COC(=O)c1cccc(N)c1O.N#CBr>>COC(=O)c1cccc2nc(N)oc12,,O,,CCO,,test
US20090042929A1,O=C(CSCc1ccc(Cl)cc1)C12CC3CC(CC(C3)C1)C2.O=C(OO)c1cccc(Cl)c1>>O=C(CS(=O)Cc1ccc(Cl)cc1)C12CC3CC(CC(C3)C1)C2,,ClCCl,,,,test
US20100210594A1,O=C([O-])Cc1ccccc1Nc1c(Cl)cccc1Cl>>O=C1Cc2ccccc2N1c1c(Cl)cccc1Cl,,O,,Cl,[Na],test
US20120184543A1,C=C(C)COc1cc(C(=O)OC)ccc1[N+](=O)[O-]>>C=C(C)Cc1c(C(=O)OC)ccc([N+](=O)[O-])c1O,,ClCCl,,,,test
US20070060613A1,CC1(C)COB(c2ccc(F)cc2)OC1.O=C(O)c1cccc(Br)n1>>O=C(O)c1cccc(-c2ccc(F)cc2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20130287686A1,NCc1ccc(F)cc1.Nc1cc(F)c(F)cc1[N+](=O)[O-]>>Nc1cc(NCc2ccc(F)cc2)c(F)cc1[N+](=O)[O-],II,CS(C)=O,,CCN(CC)CC,,test
US20020010206A1,CC(=O)c1cc(Cl)ccc1O.CCOC(=O)OCC>>CCOC(=O)CC(=O)c1cc(Cl)ccc1O,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US04788288,C=CC(=O)Cl.CCCC(N)C(OCC)OCC>>C=CC(=O)NC(CCC)C(OCC)OCC,,ClCCl,,,,test
US20080009524A1,COc1ccc(S(C)(c2ccc(OC)cc2)c2ccc(-c3cc(N)ccc3C)cc2)cc1.O=C(O)C1(c2ccc3c(c2)OCO3)CC1>>COc1ccc(S(C)(c2ccc(OC)cc2)c2ccc(-c3cc(NC(=O)C4(c5ccc6c(c5)OCO6)CC4)ccc3C)cc2)cc1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,,test
US20160096839A1,COC(OC)OC.COc1cc(-c2c(N)ccc(Cl)c2F)ncn1.[N-]=[N+]=[N-]>>COc1cc(-c2c(-n3cnnn3)ccc(Cl)c2F)ncn1,,CC(=O)O,,O,,test
US20020137689A1,CCCCCC(I)I.O=C1C(CCC(O)c2ccc(F)cc2)C(c2ccc(O)cc2)N1c1ccc(F)cc1>>O=C1C(CCC(O)c2ccc(F)cc2)C(c2ccc(OCCCCCCI)cc2)N1c1ccc(F)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150225342A1,O=C(CN1CC2CC(O)(c3ccccc3)CC2C1)c1ccccc1>>OC(CN1CC2CC(O)(c3ccccc3)CC2C1)c1ccccc1,,CCO,,[BH4-].[Na+],,test
US06303673B1,C=C1N(C)c2ccc([N+](=O)[O-])cc2C1(C)C.O=C1C(=NO)C=C(c2ccc(N3CCCC3)cc2)c2ccccc21>>CN1c2ccc([N+](=O)[O-])cc2C(C)(C)C12C=Nc1cc(-c3ccc(N4CCCC4)cc3)c3ccccc3c1O2,,Cc1ccccc1,,,,test
US20030055076A1,COC(=O)[C@H](Cc1ccc(O)cc1)Nc1ccccc1OC(=O)c1ccccc1.OCCN1c2ccccc2Sc2ccc(Cl)cc21>>COC(=O)[C@H](Cc1ccc(OCCN2c3ccccc3Sc3ccc(Cl)cc32)cc1)Nc1ccccc1C(=O)c1ccccc1,,C1CCOC1,O,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020165234A1,C1COCCN1.O=C1CCC(=O)N1O.O=C1CCc2cc(C(=O)O)ccc2C1>>NC(=O)C1CNCCO1.O=C1CCc2ccccc2C1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04612317,CCCCCCCCCCBr.OC[C@@H]1Cc2c([nH]c3ccccc23)CN1.S=C=S>>CCCCCCCCCCSC(=S)N1Cc2[nH]c3ccccc3c2C[C@H]1CO,,CS(C)=O,,CCN(CC)CC,,test
US20140148433A1,COCCBr.COc1ccc(Cn2c(=O)[nH]c3cnc(-c4nn(Cc5ccccc5F)c5ncccc45)nc32)c(OC)c1>>COCCn1c(=O)n(Cc2ccc(OC)cc2OC)c2nc(-c3nn(Cc4ccccc4F)c4ncccc34)ncc21,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20150166480A1,COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)c1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)nc2)cc1>>O=C(O)[C@@H]1C[C@@H](O)CN1C(=O)c1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CCC4)CC3)nc2)cc1,,C1CCOC1,,O,[Li]O,test
US20020147160A1,CO[C@]1(C)[C@H](OCc2ccc(Cl)cc2Cl)[C@@H](COCc2ccc(Cl)cc2Cl)O[C@H]1n1cc(C)c2c(Cl)nc(N)nc21.[OH-]>>CO[C@]1(C)[C@H](OCc2ccc(Cl)cc2Cl)[C@@H](COCc2ccc(Cl)cc2Cl)O[C@H]1n1cc(C)c2c(=O)[nH]c(N)nc21,,[Na+],[OH-],C1COCCO1,Cl,test
US20090181963A1,COC(Cn1nnc2c(N3CCOCC3)nc(-c3ccc(N)cc3)nc21)OC.O=C=Nc1cccnc1>>COC(Cn1nnc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4cccnc4)cc3)nc21)OC,,ClCCl,,CCN(CC)CC,,test
US05616610,COc1ccc(F)c2c1C[C@@H](NC1CCCC1)CO2.O=C1CCC1>>COc1ccc(F)c2c1C[C@@H](N(C1CCCC1)C1CCC1)CO2,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US05656573,C=C(C)c1c(Cl)ccc(C(=O)OC)c1SC>>C=C(C)c1c(Cl)ccc(C(=O)O)c1SC,,O,,CCO,[Na+].[OH-],test
US20010039285A1,COc1ccc2c(c1)CCNC2c1ccccc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccc2c(c1)CCN(C(=O)C(F)(F)F)C2c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US05180824,Nc1nc(F)nc2nc[nH]c12.O=C(OC1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1)c1ccc([N+](=O)[O-])cc1>>Nc1nc(F)nc2c1ncn2[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05607960,CCC(=O)C=Cc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1>>CCC(=O)CCc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1,[Pd],O,,,,test
US20140005172A1,CC(C)(C)OC(=O)N1CCOc2ccc(B(O)O)cc2C1.CS(=O)(=O)Nc1cc(Br)cnc1Cl>>CC(C)(C)OC(=O)N1CCOc2ccc(-c3cnc(Cl)c(NS(C)(=O)=O)c3)cc2C1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20140057914A1,CC[N+](=O)[O-].O=CCc1cccc(Br)c1>>CC(C(O)Cc1cccc(Br)c1)[N+](=O)[O-],,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20100144760A1,Cc1ccc(-c2ncc(C)o2)c(C(=O)N2C[C@@H]3C[C@@H]3C[C@H]2CNc2ncc(C(F)(F)F)cn2)n1.Cl>>Cc1ccc(-c2ncc(C)o2)c(C(=O)N2C[C@@H]3C[C@@H]3C[C@H]2CNc2ncc(C(F)(F)F)cn2)n1.Cl,,ClCCl,,,,test
US06051288,CC[C@@H]1CC[C@@H](C(=O)O)CC1.O=S(Cl)Cl>>CC[C@@H]1CC[C@@H](C(=O)Cl)CC1,,Cc1ccccc1,,c1ccncc1,,test
US20120088767A1,BrCc1cccc2ccccc12.COC(=O)c1cc(N2CCOCC2)cc2nc(C(F)F)[nH]c12>>COC(=O)c1cc(N2CCOCC2)cc2c1nc(C(F)F)n2Cc1cccc2ccccc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070093476A1,CS(=O)(=O)Oc1ccc([N+](=O)[O-])c(OCCBr)c1>>CS(=O)(=O)Oc1ccc(N)c(OCCBr)c1,[Pd],CCOC(C)=O,,,,test
US20050245741A1,CC(=O)Cl.Cc1nc2ccc(O)cc2o1>>CC(=O)Oc1ccc2nc(C)oc2c1,,C1CCOC1,,CCN(CC)CC,,test
US05811389,COc1ccc2c(c1CNC(=O)CNC(=O)[C@@H](NC(=O)OCc1ccccc1)[C@@H](C)OC(C)(C)C)Oc1c(ccc(OC)c1CC(=O)OCc1ccccc1)C2(C)C>>COc1ccc2c(c1)Oc1c(ccc(OC)c1CC(=O)O)C2(C)C,[Pd],CO,,,,test
US20060111553A1,N#Cc1ccc(CN)cc1.N=C(c1ccccc1)c1ccccc1>>N#Cc1ccc(CN=C(c2ccccc2)c2ccccc2)cc1,,ClCCl,,,,test
US20090291917A1,COc1nc(Oc2ccc(B3OC(C)(C)C(C)(C)O3)c(C=O)c2)ccc1C(N)=O>>COc1nc(Oc2ccc3c(c2)COB3O)ccc1C(N)=O,,CO,ClCCl,[BH4-].[Na+],,test
US20140088078A1,CC(C)(C)OC(=O)N1CC[C@H](OCc2cc(F)ccc2S(=O)(=O)Cl)C1.COC(=O)c1c(N)ccc2c1OC[C@@H]1C[C@H]21>>COC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2CO[C@H]2CCN(C(=O)OC(C)(C)C)C2)ccc2c1OC[C@@H]1C[C@H]21,,ClCCl,,,,test
US05733914,COc1ccc(N)cn1.Cn1c(=O)c(-c2c(Cl)cccc2Cl)cc2cnc(S(C)(=O)=O)nc21>>COc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cn1,,O,,,,test
US04837217,CC(C)(C)n1ncc(S)c(Cl)c1=O.COCCOc1ccc(CBr)cc1>>COCCOc1ccc(CSc2cnn(C(C)(C)C)c(=O)c2Cl)cc1,,CCO,,O,O=C([O-])[O-].[Na+].[Na+],test
US20150133446A1,CC(C)(C)OC(=O)N1CCC[C@@H]1CO.CSc1nn2cc(-c3nc4c(O)cccc4o3)nc2s1>>CSc1nn2cc(-c3nc4c(OC[C@H]5CCCN5C(=O)OC(C)(C)C)cccc4o3)nc2s1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070073061A1,CC(C)(C)OC(=O)N1CCC(=C2C(=O)OC(C)(C)OC2=O)CC1.Cc1ccc([Mg]Br)cc1F>>Cc1ccc(C2(C3C(=O)OC(C)(C)OC3=O)CCN(C(=O)OC(C)(C)C)CC2)cc1F,,C1CCOC1,,,,test
US04623658,CCCC(=O)N(C)SNc1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1F.O=C=NC(=O)c1c(F)cccc1F>>CCCC(=O)N(C)SN(C(=O)NC(=O)c1c(F)cccc1F)c1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1F,,Cc1ccccc1,,,,test
US20040171881A1,CCN(CC)CC.COC(=O)c1cc(C)cc(CO)c1>>COC(=O)c1cc(C)cc(CN(C)CCO)c1,,ClCCl,,CS(=O)(=O)Cl,,test
US04227000,COc1cc[n+]([O-])c(C)c1OC>>COc1ccnc(CO)c1OC,,ClCCl,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US20110190309A1,Nc1cnccn1.O=C(Cl)CCl>>O=C(CCl)Nc1cnccn1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20020082265A1,CC1CCC(C(C)C)C(c2ccc3c(c2)C(C2CC(C)CCC2C(C)C)(C2CC(C)CCC2C(C)C)C(=O)CC3(C2CC(C)CCC2C(C)C)C2CC(C)CCC2C(C)C)C1>>Cc1ccc2c(c1)C(C)(C)C(O)CC2(C)C,,CCO,,[BH4-].[Na+],,test
US20060270663A1,CC(=O)c1ccc(C)c([N+](=O)[O-])c1>>CC(=O)c1ccc(C)c(N)c1,[Fe],CCO,O,[Cl-].[NH4+],,test
US05942520,CCn1nccc1N.O=C(O)c1cc([N+](=O)[O-])ccc1Cl>>CCn1nccc1Nc1ccc([N+](=O)[O-])cc1C(=O)O,,CC(=O)O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US06235771B1,CCCBr.CCOc1cc(Br)ccc1O>>CCCOc1ccc(Br)cc1OCC,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20150057260A1,COC(=O)c1ncc(F)cc1NC1COC1.O=C1CCC(=O)N1Br>>COC(=O)c1nc(Br)c(F)cc1NC1COC1,,CC#N,,,,test
US04977162,ClCc1ccc2ccccc2n1.OCc1cccc(O)c1>>OCc1cccc(OCc2ccc3ccccc3n2)c1,,CS(C)=O,,Cl,[Na+].[OH-],test
US20070032494A1,CC(C)c1cc(Cl)nnc1Cl.OCCc1cc(Br)c(O)c(Br)c1>>CC(C)c1cc(Oc2c(Br)cc(CCO)cc2Br)nnc1Cl,,CC(=O)N(C)C,O,CC(C)(C)[O-].[K+],,test
US20030204090A1,Cc1cc(Cl)ccn1.OCc1ccccc1>>Cc1cc(OCc2ccccc2)ccn1,,CN(C)C=O,,[H-].[Na+],,test
US04507498,CCCc1c(OCC(=O)OCC)ccc(C(C)=O)c1O.ClCCOCCCl>>CCCc1c(OCC(=O)OCC)ccc(C(C)=O)c1OCCOCCCl,,CC(C)=O,CN(C)C=O,[I-].[K+],,test
US20130345431A1,C=CCCCCCCCC.Cc1ccc(N=[N+]=[N-])cc1>>CCCCCCCCC1CN1c1ccc(C)cc1,,,,,,test
US20130102611A1,CCOC(=O)CCCCCCN1CCC(OC(C)=O)c2nc(-c3ccc(C)cc3)c(-c3ccc(C)cc3)nc21>>Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)N(CCCCCCC(=O)O)CCC3O)cc1,,CCO,,Cl,[Na+].[OH-],test
US20130281490A1,C[C@H](O)[C@@H](NC(=O)OCCCCCCc1ccccc1)C(=O)O>>C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCCCc1ccccc1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20110028467A1,O=S(=O)(Cl)c1cc(Cl)c(O)c(Cl)c1.c1cc2c(cn1)NCCO2>>O=S(=O)(c1cc(Cl)c(O)c(Cl)c1)N1CCOc2ccncc21,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20040133008A1,CNC.Cc1ccc(C(=O)Nc2ccc(N(CCc3cccc(NC(=O)OC(C)(C)C)n3)C(=O)OC(C)(C)C)cc2)c(Cl)n1>>Cc1ccc(C(=O)Nc2ccc(N(CCc3cccc(NC(=O)OC(C)(C)C)n3)C(=O)OC(C)(C)C)cc2)c(N(C)C)n1,,C1CCOC1,,,,test
US04303655,CCOC(=O)C(=O)c1csc(NS(C)(=O)=O)n1>>CCOC(=O)C(O)c1csc(NS(C)(=O)=O)n1,,CCO,,[BH4-].[Na+],,test
US20120270863A1,CCOC(=O)CNC(=O)c1cc(OC)c(OC)cc1I>>COc1cc(I)c(C(=O)NCCO)cc1OC,,C1CCOC1,,CO,[BH4-].[Li+],test
US05576321,ClCCOc1cccc2[nH]ccc12.Clc1ccc2c(C3=CCNCC3)c[nH]c2c1.O=C(O)C(=O)O>>Clc1ccc2c(C3=CCN(CCOc4cccc5[nH]ccc45)CC3)c[nH]c2c1.O=C(O)C(=O)O,,CCOCC,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100234367A1,O=C1c2ccccc2C(=O)N1[C@H]1CCC[C@H](c2cccnc2)C1>>N[C@H]1CCC[C@H](c2cccnc2)C1,,CCO,,,,test
US20100061928A1,CCOC(=O)Nc1cc(I)c(N)cc1OC.CS(=O)(=O)Cl>>CCOC(=O)Nc1cc(I)c(NS(C)(=O)=O)cc1OC,,c1ccncc1,,,,test
US20050014767A1,CC(=O)OC(C)=O.Nc1cc(-c2ccc(C3OCCO3)cn2)cc(C23CC4CC(CC(C4)C2)C3)c1O>>Cc1nc2cc(-c3ccc(C=O)cn3)cc(C34CC5CC(CC(C5)C3)C4)c2o1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090298823A1,CN.Cc1ccc(S(=O)(=O)n2cc(I)c3c(Cl)nc(Cl)nc32)cc1>>CNc1nc(Cl)nc2c1c(I)cn2S(=O)(=O)c1ccc(C)cc1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20140243336A1,CC(C)(C)OC(=O)N[C@@H](CNC(=O)OCc1ccccc1)C(=O)O.CNC>>CN(C)C(=O)C(CNC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04548940,Cc1cc(Cl)cnc1NCCCCN.Cc1ccc(Cc2cnc(N[N+](=O)[O-])[nH]c2=O)cn1>>Cc1ccc(Cc2cnc(NCCCCNc3ncc(Cl)cc3C)[nH]c2=O)cn1,,O,,Cl,,test
US20120202834A1,CCC[C@@H](O)c1ccc(C(=O)OC)cc1.CS(=O)(=O)Cl>>CCC[C@@H](OS(C)(=O)=O)c1ccc(C(=O)OC)cc1,,COC(C)(C)C,,CCN(CC)CC,,test
US04704477,CC1=CCC(C)(C(=O)Cl)C(C)C1.CO>>COC(=O)C1(C)CC=C(C)CC1C,,Cc1ccccc1,O,Cl,c1ccncc1,test
US05827863,CCCCn1nc(C)c(C(=O)OC)c1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1>>CCCCn1nc(C)c(C(=O)O)c1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1,,CCO,,[Na+].[OH-],,test
US20120071482A1,CC(C)(C)[Si](C)(C)O[C@H]1C[C@H](N)C[C@H]1COCc1ccccc1.CO[C@H]1Cc2ccccc2[C@H]1Nc1nc(Cl)nc(Cl)n1>>CO[C@H]1Cc2ccccc2[C@H]1Nc1nc(Cl)nc(N[C@H]2CC(O[Si](C)(C)C(C)(C)C)[C@H](COCc3ccccc3)C2)n1,,C1CCOC1,,CCN(CC)CC,,test
US20130096118A1,Cc1c(C#N)cccc1[N+](=O)[O-]>>Cc1c(N)cccc1C#N,[Zn],C1CCOC1,CO,[Cl-].[NH4+],,test
US20090124698A1,COCOc1ccc(/C(C(=O)Nc2ccc(OCCN(C)C)cc2)=C(/CCO[Si](C(C)C)(C(C)C)C(C)C)c2ccccc2)cc1>>COCOc1ccc(/C(C(=O)Nc2ccc(OCCN(C)C)cc2)=C(/CCO)c2ccccc2)cc1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20040077669A1,CC#CCOc1cc(Cl)ncn1.Oc1cccc2c1OCO2>>CC#CCOc1cc(Oc2cccc3c2OCO3)ncn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100261755A1,COC(=O)C1CCNC(Cc2ccccc2C(F)(F)F)C1.COC(=O)Cl>>COC(=O)C1CCN(C(=O)OC)C(Cc2ccccc2C(F)(F)F)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100069381A1,O=C(CCc1ccccc1)Nc1cc(C(=O)NNC(=O)OCc2ccccc2)ccn1>>NNC(=O)c1ccnc(NC(=O)CCc2ccccc2)c1,[Pd],C1CCOC1,,CO,,test
US04966902,ClCCBr.N#CCc1ccc(Cl)nc1>>N#CC1(c2ccc(Cl)nc2)CC1,,C1CCOC1,,[H-].[Na+],,test
US20090036450A1,CC(N)=S.O=C1CCN(C(=O)OCc2ccccc2)CC1Br>>Cc1nc2c(s1)CN(C(=O)OCc1ccccc1)CC2,,CN(C)C=O,,O,,test
US20130109789A1,COCC1(C(C)(C)C(C)C)COC(C)(C)OC1.C[Mg]I>>COCC(CO)(COC(C)(C)C)C(C)(C)C(C)C,,Cc1ccccc1,,CCOCC,,test
US05453443,C1=COCCC1.CCCCCOC(COc1ccc(C(=O)C(F)(F)F)cc1)COc1ccc(C(CCCc2ccccc2)SCCC(=O)O)cc1>>c1ccc(CCCC(OC2CCCCO2)c2ccc(OCC3CO3)cc2)cc1,,ClCCl,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20160237095A1,CC(C)(C)OC(=O)n1ncc2cc(N)ccc21.Clc1cc(Cl)ncn1>>Clc1cc(Nc2ccc3[nH]ncc3c2)ncn1,,O,,CCN(C(C)C)C(C)C,CN(C)C=O,test
US20110152237A1,CCOC(=O)C(CC=C1CCOCC1)NS(=O)(=O)c1ccc([N+](=O)[O-])cc1>>CCOC(=O)C1CCC2(CCOCC2)N1S(=O)(=O)c1ccc([N+](=O)[O-])cc1,,ClC(Cl)Cl,ClCCl,O=S(=O)(O)C(F)(F)F,,test
US20100204196A1,COc1cc([N+](=O)[O-])c(OC)cc1N1CCN(C(C)C)CC1>>COc1cc(N2CCN(C(C)C)CC2)c(OC)cc1N,,CO,,NN,O,test
US20060094751A1,Nc1cc(F)c(F)cc1F.O=Cc1ccc(Br)s1>>Fc1cc(F)c(NCc2ccc(Br)s2)cc1F,,CCO,CO,[BH4-].[Na+],,test
US06211199B1,C1CCOC1.CCOC(=O)CBr.CCOCC.N#CCc1ccccc1>>CCOC(=O)CC(C#N)(CC(=O)OCC)c1ccccc1,,C1CCOC1,CCOCC,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US04918074,CCOC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(C)=O.CCOC(=O)c1nc[nH]c1N>>CCOC(=O)C1=C(C)Nc2c(C(=O)OCC)ncn2C1c1cccc([N+](=O)[O-])c1,,CCO,,,,test
US04800201,CC1=CSCC(=O)N1.CCOC(=O)Cl.c1cscn1>>CCOC(=O)N1CCSC1C1=C(C)NC(=O)CS1,,ClCCl,,,,test
US20090131420A1,CI.O=C1COCC(Cc2ccc(OCc3ccccc3)cc2)N1>>CN1C(=O)COCC1Cc1ccc(OCc2ccccc2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20060100262A1,COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccccc3CNCCN(C)C)n(CC(=O)OC(C)(C)C)c2c1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccccc3CNCCN(C)C)n(CC(=O)O)c2c1,,ClCCl,O,O=C(O)C(F)(F)F,,test
US20090029958A1,CC(C)(C)[Si](C)(C)O[C@@H](CNC1CCN(CCC(=O)O)CC1)c1ccc(O)c2[nH]c(=O)ccc12.Cc1cc(C)cc(CN)c1>>Cc1cc(C)cc(CNC(=O)CCN2CCC(NC[C@H](O)c3ccc(O)c4[nH]c(=O)ccc34)CC2)c1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130065861A1,CCCCCCCCCCCCOC[C@H](CSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NCCOCCOCCC(F)(F)P(=O)(OCC)OCC)NC(=O)CCCCCCCCCCC>>CCCCCCCCCCCCOC[C@H](CSC[C@H](N)C(=O)NCCOCCOCCC(F)(F)P(=O)(OCC)OCC)NC(=O)CCCCCCCCCCC,,CC#N,,C1CCNCC1,,test
US20140364411A1,CC(C)[Si](OCC1CCN(c2nnc3ccc(O[C@@H]4CC[C@H](N)c5ccccc54)cn23)CC1)(C(C)C)C(C)C.Cn1nc(C(C)(C)C)cc1NC(=O)OCC(Cl)(Cl)Cl>>CC(C)[Si](OCC1CCN(c2nnc3ccc(O[C@@H]4CC[C@H](NC(=O)Nc5cc(C(C)(C)C)nn5C)c5ccccc54)cn23)CC1)(C(C)C)C(C)C,,C1COCCO1,ClCCl,CCN(C(C)C)C(C)C,,test
US20110178304A1,CC(C)(C)OC(=O)NC1CCNCC1.O=Cc1ccc2c(c1)NC(=O)CC2>>CC(C)(C)OC(=O)NC1CCN(Cc2ccc3c(c2)NC(=O)CC3)CC1,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20060287522A1,Cc1cc(C(=O)N2Cc3ccc(C(=O)C(Cl)(Cl)Cl)n3Cc3ccccc32)ccc1-c1c(C)cccc1C.NCc1cccnc1>>Cc1cc(C(=O)N2Cc3ccc(C(=O)NCc4cccnc4)n3Cc3ccccc32)ccc1-c1c(C)cccc1C,,CC#N,,CCN(CC)CC,CS(C)=O,test
US20140350019A1,COC(=O)c1cc(Br)cc(C(N)=O)c1>>COC(=O)c1cc(Br)cc(C#N)c1,,O=P(Cl)(Cl)Cl,,,,test
US20120101086A1,CC(C)(C)OC(=O)CBr.Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(C#N)c3)s1)CCNC2>>Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(C#N)c3)s1)CCN(CC(=O)OC(C)(C)C)C2,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20070208003A1,CC(=O)OC(C)=O.CC(C)OC(=O)N1CCCC(NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2cscc21>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)C)c2cscc21,,CCOC(C)=O,ClCCl,c1ccncc1,,test
US20100184815A1,Cc1ccc(CN(N)C(N)=O)cc1.O=C(Cl)COCc1ccccc1>>Cc1ccc(CN(NC(=O)COCc2ccccc2)C(N)=O)cc1,,CCOC(C)=O,,Cl,c1ccncc1,test
US20040063704A1,COc1cc(N)ccc1F.O=C1CCC(=O)N1Br>>COc1cc(N)c(Br)cc1F,,ClCCl,,,,test
US07105680B1,COCOc1ccc(OC)cc1-c1nc2c(CBr)cccc2o1.NCc1ccccn1>>COCOc1ccc(OC)cc1-c1nc2c(CNCc3ccccn3)cccc2o1,,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20090318714A1,CC1=NCC(=O)O1.CN(C)C(N(C)C)N(C)C.COCCCOc1cc(C(=O)CC(C)C)ccc1OC>>COCCCOc1cc(-c2oc(=O)c(NC(C)=O)cc2C(C)C)ccc1OC,,Cc1ccccc1,,CCN(CC)CC,,test
US20090131458A1,CO.Nc1nc(Cl)nc2c1nc(Br)n2CC1CCOCC1>>COc1nc2c(N)nc(Cl)nc2n1CC1CCOCC1,,CO,CS(C)=O,[Na+].[OH-],,test
US20100125061A1,CCS(=O)(=O)Cl.COC(=O)Cc1cc2ccc(F)cc2c(C(=O)N2CCNCC2)c1C>>CCS(=O)(=O)N1CCN(C(=O)c2c(C)c(CC(=O)OC)cc3ccc(F)cc23)CC1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20090082434A1,Cc1ccc(S(=O)(=O)OCC2Cc3cccc(Br)c3O2)cc1.OB(O)c1cccc(Cl)c1>>Cc1ccc(S(=O)(=O)OCC2Cc3cccc(-c4ccccc4Cl)c3O2)cc1,Cc1ccccc1[P](c1ccccc1C)(c1ccccc1C)[Pd](Cl)(Cl)[P](c1ccccc1C)(c1ccccc1C)c1ccccc1C,,,O=C([O-])[O-].[K+].[K+],,test
US20060046985A1,Cl.N=C1CCCCN1OCc1ccccc1>>Cl.N=C1CCCCN1O,[Pd],CO,,,,test
US20140343019A1,C=CCC[Mg]Br.CON(C)C(=O)C1CC(OC)(OC)C1>>C=CCCC(=O)C1CC(OC)(OC)C1,,C1CCOC1,,,,test
US20130178499A1,C[Si](C)(C)N=[N+]=[N-].N#Cc1ccc(-c2cc(Cl)c3cc(O)ccc3n2)cc1>>Oc1ccc2nc(-c3ccc(-c4nn[nH]n4)cc3)cc(Cl)c2c1,,Cc1ccccc1,,,,test
US20100009986A1,Fc1ccc2[nH]cc(CCBr)c2c1.c1c[nH]cn1>>Fc1ccc2[nH]cc(CCn3ccnc3)c2c1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20120264734A1,C1COCCN1.CCN(c1cc(-c2cccc(C=O)c2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1>>CCN(c1cc(-c2cccc(CN3CCOCC3)c2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1,,CC(Cl)Cl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100056502A1,CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)[C@H]1CCN(C(=O)OCc2ccccc2)C[C@H]1O>>CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)[C@H]1CCNC[C@H]1O,[Pd],CCO,,,,test
US20090099180A1,O=C1N(Cc2c(Cl)cc(O)cc2Cl)CCC12CCCCC2.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=C1N(Cc2c(Cl)cc(OS(=O)(=O)C(F)(F)F)cc2Cl)CCC12CCCCC2,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US05919986,C[C@H](CC#CC(C)(C)O)C1=CCC[C@H]2C(=O)CCC[C@]12C.C[Si](C)(C)c1ncc[nH]1>>C[C@H](CC#CC(C)(C)O[Si](C)(C)C)C1=CCC[C@H]2C(=O)CCC[C@]12C,,ClCCl,,,,test
US05098918,COc1ccc(CC(=O)Cl)cc1.c1ccoc1>>COc1ccc(CC(=O)c2ccco2)cc1,,ClCCl,,O=S(=O)(O)C(F)(F)F,,test
US20090018122A1,CCOCc1nc2c[n+]([O-])c3ccc(OCc4ccccc4)cc3c2n1CC(C)(C)NC(=O)C1CCCCC1.O=C=NC(=O)C(Cl)(Cl)Cl>>CCOCc1nc2c(N)nc3ccc(OCc4ccccc4)cc3c2n1CC(C)(C)NC(=O)C1CCCCC1,,ClCCl,,,,test
US20130012491A1,CC(C)Oc1ccc(-c2ncc(Br)cn2)cc1Cl.CCc1c(B2OC(C)(C)C(C)(C)O2)cccc1C1CCNCC1>>CCc1c(-c2cnc(-c3ccc(OC(C)C)c(Cl)c3)nc2)cccc1C1CCNCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080004302A1,Cc1cc(CNc2nccc(Cl)n2)on1.Cc1csc(CCc2cc(N)[nH]n2)c1>>Cc1csc(CCc2cc(Nc3ccnc(NCc4cc(C)no4)n3)[nH]n2)c1,,CCO,,,,test
US20070123561A1,CC(C)(C)N(CCOc1ccc(-n2c(-c3nonc3N)nc3cnccc32)cc1)C(=O)[O-]>>NCCOc1ccc(-n2c(-c3nonc3N)nc3cnccc32)cc1,,C1COCCO1,,Cl,,test
US20090124600A1,BrCCOCc1ccccc1.CC(C)(C)OC(=O)NC1CCNC1>>CC(C)(C)OC(=O)NC1CCN(CCOCc2ccccc2)C1,,ClCCl,,[Na+].[OH-],,test
US20160075695A1,Cc1noc(C)c1-c1cc(I)c2nc(C3CC3)n(C(=O)OC(C)(C)C)c2c1.O=C(c1ccccn1)[C@H]1CCC2(CC2)O1>>Cc1noc(C)c1-c1cc([C@](O)(c2ccccn2)[C@H]2CCC3(CC3)O2)c2nc(C3CC3)n(C(=O)OC(C)(C)C)c2c1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20160075722A1,COc1ccnc(Cl)c1.O=Cc1ccc(OCc2ccccc2)c(B(O)O)c1>>COc1ccnc(-c2cc(C=O)ccc2OCc2ccccc2)c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20150197539A1,CCN(CC)C(=O)c1cccc(O)c1.COCCl>>CCN(CC)C(=O)c1cccc(OCOC)c1,,ClCCl,,CC(C)NC(C)C,,test
US20110306599A1,CC(=O)Cl.CNc1ccc2cc(-c3nn(COCC[Si](C)(C)C)c4c3CCC(C)(C)C4)n(COCC[Si](C)(C)C)c2c1>>CC(=O)N(C)c1ccc2cc(-c3nn(COCC[Si](C)(C)C)c4c3CCC(C)(C)C4)n(COCC[Si](C)(C)C)c2c1,,ClC(Cl)Cl,,CCN(CC)CC,O,test
US20120252777A1,COC(=O)c1cccc(B2OC(C)(C)C(C)(C)O2)c1.Clc1nc(Nc2cccc(N3CC4(COC4)C3)c2)c2ncsc2n1>>COC(=O)c1cccc(-c2nc(Nc3cccc(N4CC5(COC5)C4)c3)c3ncsc3n2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US04839376,CCN(CC)CC.Nc1cccnc1.S=C=S>>CC[NH+](CC)CC.S=C([S-])Nc1cccnc1,,c1ccccc1,,,,test
US20060252811A1,CC(=O)OC(C)=O.Fc1cccc(CN(CCN2CCNCC2)Cc2nccn2Cc2cc(Cl)cc(Cl)c2)c1>>CC(=O)N1CCN(CCN(Cc2cccc(F)c2)Cc2nccn2Cc2cc(Cl)cc(Cl)c2)CC1,,ClCCl,,O=C([O-])O.[Na+],,test
US20120208817A1,Br[Mg]c1ccccc1.COc1ccc(CC(=O)N(C)OC)cc1OC>>COc1ccc(CC(=O)c2ccccc2)cc1OC,,C1CCOC1,,,,test
US20100063293A1,CC(NC(=O)c1cc(Cl)ccc1NC(=O)C1CC(O)=NN1c1ncccc1Cl)C1CC1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC2=NN(c3ncccc3Cl)C(C(=O)Nc3ccc(Cl)cc3C(=O)NC(C)C3CC3)C2)cc1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20070072914A1,CC(O)c1cccc(NC(=O)C(C)(C)C)n1>>Nc1cccc(CO)n1,,C1COCCO1,,Cl,,test
US20100080771A1,C=Cc1ccccc1-c1ccc(Br)cc1.COC(=O)[C@@H]1CC(=O)CN1C(=O)OCC[Si](C)(C)C>>C=Cc1ccccc1-c1ccc([C@]2(O)C[C@@H](C(=O)OC)N(C(=O)OCC[Si](C)(C)C)C2)cc1,,C1CCOC1,Cc1ccccc1,[Mg],,test
US20050153970A1,CNCCCc1ccc(F)cc1.Cc1ccc(S(=O)(=O)OC[C@@H]2CCCC[C@H]2NC(=O)OCc2ccccc2)cc1>>CN(CCCc1ccc(F)cc1)C[C@@H]1CCCC[C@H]1NC(=O)OCc1ccccc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040067966A1,CCCn1c(=O)c2[nH]c(C34CCC(NC(=O)OC)(CC3)CC4)nc2n(CCC)c1=O>>CCCn1c(=O)c2[nH]c(C34CCC(N)(CC3)CC4)nc2n(CCC)c1=O,,Cl,,,,test
US20020028841A1,CCOC(=O)CCl.O=[N+]([O-])c1cccs1>>CCOC(=O)Cc1ccsc1[N+](=O)[O-],,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20090054469A1,Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1N.Cn1cnc2ccc(C(=O)O)cc2c1=O>>Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1NC(=O)c1ccc2ncn(C)c(=O)c2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080161278A1,CCc1cc(Cl)nc(Cl)n1.Cc1cc(N)n[nH]1>>CCc1cc(Nc2cc(C)[nH]n2)nc(Cl)n1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20130035325A1,CC(C#N)C(N)=O.O=CC1CCN(c2ncnc3[nH]cnc23)CC1>>CNC(=O)C(C#N)=CC1CCN(c2ncnc3[nH]cnc23)CC1,,C1CCOC1,CCOC(C)=O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20120264748A1,Cc1ccc(S(=O)(=O)n2cc(CCl)c3ccccc32)cc1.O=C1NCCCC12CCN(c1nc3ccccc3o1)CC2>>O=C1N(Cc2c[nH]c3ccccc23)CCCC12CCN(c1nc3ccccc3o1)CC2,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20100190766A1,CC(C)(C)[Si](C)(C)Cl.OCc1ccc(I)cc1>>CC(C)(C)[Si](C)(C)OCc1ccc(I)cc1,,CN(C)C=O,ClCCl,c1c[nH]cn1,,test
US06147088,COC(=O)c1ccc(Cl)cc1NC(=O)Cc1cc(C)cc(C)c1>>Cc1cc(C)cc(-c2c(O)c3ccc(Cl)cc3[nH]c2=O)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20090298825A1,CC(C)(C)OC(=O)N1CCC(n2ccc3c(NC(=O)CC4CCCCCC4)cccc3c2=O)CC1>>O=C(CC1CCCCCC1)Nc1cccc2c(=O)n(C3CCNCC3)ccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050026970A1,CN1CN=C2C=C(Nc3ccc(I)cc3F)C(F)(C(=O)Oc3c(F)c(F)c(F)c(F)c3F)C=C21.N>>CN1CN=C2C=C(Nc3ccc(I)cc3F)C(F)(C(N)=O)C=C21,,CN(C)C=O,,,,test
US20120010183A1,CCOC(=O)c1cc(F)c(Oc2cnc(OCC(C)C)c(Cl)c2)cc1F>>CC(C)COc1ncc(Oc2cc(F)c(C(=O)O)cc2F)cc1Cl,,O,,C1CCOC1,[Li+].[OH-],test
US20120245144A1,CC(CS(=O)(=O)[O-])c1ccc2c(c1)-c1nc(-c3ncnn3C(C)C)cn1CCO2.OC1CNC1>>CC(c1ccc2c(c1)-c1nc(-c3ncnn3C(C)C)cn1CCO2)N1CC(O)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070105819A1,Cl[Mg]C1CCCCC1.O=C(NCc1cccc(Cl)c1)c1ccc2c(c1)N=C(Cl)c1cc(F)ccc1S2>>O=C(NCc1cccc(Cl)c1)c1ccc2c(c1)N=C(C1CCCCC1)c1cc(F)ccc1S2,[Fe],,,,,test
US20040067964A1,CSc1cnc2c(c1)cc([Si](C)(C)C)n2S(=O)(=O)c1ccccc1>>CSc1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20090023743A1,CCOC(=O)CCc1nc(I)c2c(Cl)nccn12>>O=C(O)CCc1nc(I)c2c(Cl)nccn12,,C1CCOC1,CCO,Cl,[Li+].[OH-],test
US04584375,C(=NC1CCCCC1)=NC1CCCCC1.CO>>CCCCCCCCCCN,CO,,,On1nnc2ccccc21,,test
US20130053366A1,CC(=O)c1ccc2[nH]c3c(c2c1)CN(C)CC3.c1cc(C2CO2)ccn1>>CC(=O)c1ccc2c(c1)c1c(n2CC(O)c2ccncc2)CCN(C)C1,,CN(C)C=O,,[H-].[Na+],,test
US06310221B1,CC(=O)OC[C@H]1OC[C@@](O)(COC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>OC[C@H]1OC[C@@](O)(CO)[C@@H](O)[C@@H]1O,,ClC(Cl)Cl,,C[O-].[Na+],,test
US07238714B2,COC(=O)c1ccc([C@H](C)NC(=O)c2cc(Cl)cnc2Oc2cccc(F)c2)cc1>>C[C@H](NC(=O)c1cc(Cl)cnc1Oc1cccc(F)c1)c1ccc(C(=O)O)cc1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20070249670A1,COC(=O)c1sc(-c2cc(F)c(F)c(F)c2)cc1N>>Nc1cc(-c2cc(F)c(F)c(F)c2)sc1C(=O)O,,C1COCCO1,CCOC(C)=O,Cl,[Li+].[OH-],test
US20100234367A1,O=C1CCC(c2ccccn2)C1>>O[C@H]1CC[C@H](c2ccccn2)C1,,CO,,[BH4-].[Na+],,test
US20150315198A1,Cc1cnn(Cc2ccc(Cn3cc4c(Cl)ncnc4n3)cc2)c1.NCc1ccc2ccc(Cl)cc2c1>>Cc1cnn(Cc2ccc(Cn3cc4c(NCc5ccc6ccc(Cl)cc6c5)ncnc4n3)cc2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20090023725A1,CCNC(=O)c1cc(F)c(C)c(-c2ccc3c(Br)n[nH]c3c2)c1.COc1ncccc1B(O)O>>CCNC(=O)c1cc(F)c(C)c(-c2ccc3c(-c4cccnc4OC)n[nH]c3c2)c1,,CC(C)O,,O=C([O-])O.[Na+],,test
US20150315198A1,COc1ccc(C#N)c(CBr)c1F.Cc1cc(C)n(Cc2ccc(Cn3cc4c(N)ncnc4n3)cc2)n1>>COc1ccc(C#N)c(CNc2ncnc3nn(Cc4ccc(Cn5nc(C)cc5C)cc4)cc23)c1F,,CN(C)C=O,,,,test
US04843072,ClCC1CO1.N#Cc1ccc(Cl)cc1O>>N#Cc1ccc(Cl)cc1OCC1CO1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20130102576A1,COC(=O)CBr.COc1ccc2c(c1)C(=O)C(=O)N2>>COC(=O)CN1C(=O)C(=O)c2cc(OC)ccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130059832A1,Cc1ccc(-c2noc(C3CN(S(=O)(=O)NC(=O)OC(C)(C)C)C3)n2)cc1NC(=O)c1cnc2ccccn12>>Cc1ccc(-c2noc(C3CN(S(N)(=O)=O)C3)n2)cc1NC(=O)c1cnc2ccccn12,,CC#N,,Cl,,test
US20130143876A1,CCNC(=O)C(C)c1ccc(I)cc1.OB(O)c1ccncc1>>CCNC(=O)C(C)c1ccc(-c2ccncc2)cc1,,C1COCCO1,CO,O,O=C([O-])[O-].[Na+].[Na+],test
US20040157886A1,N#Cc1cccc(NC(=O)CCl)c1.c1ccc(CC2CCNCC2)cc1>>N#Cc1cccc(NC(=O)CN2CCC(Cc3ccccc3)CC2)c1,,CCOCC,,,,test
US05264439,CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(OC(C(=O)OC)c2ccccc2)c(CCC)c1>>CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(OC(C(=O)O)c2ccccc2)c(CCC)c1,,CO,ClCCl,,,test
US20090082464A1,CC(=O)NCCCS(=O)(=O)OCC(C)(C)COCc1ccccc1>>CC(=O)NCCCS(=O)(=O)OCC(C)(C)CO,[Pd],CO,,[H][H],,test
US20100204196A1,CCN(C)CC(=O)N1CCc2cc(OC)c(N)cc21.Cc1ccc(S(=O)(=O)n2ccc3c2nc(Cl)n2c(=O)c4c(F)cccc4nc32)cc1>>CCN(C)CC(=O)N1CCc2cc(OC)c(Nc3nc4c(ccn4S(=O)(=O)c4ccc(C)cc4)c4nc5cccc(F)c5c(=O)n34)cc21,,C1CCOC1,CCOC(C)=O,,,test
US04450115,CC(N)CCc1ccccc1.N#Cc1ccccc1OCC1CO1>>CC(CCc1ccccc1)NCC(O)COc1ccccc1C#N,,CCO,,,,test
US20120220609A1,Brc1ccc(Br)nc1.Cc1nc(CC2CCNCC2)nc(C(=O)OC(C)(C)C)c1OCc1ccccc1>>Cc1nc(CC2CCN(c3ccc(Br)cn3)CC2)nc(C(=O)OC(C)(C)C)c1OCc1ccccc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US03941803,C=O.Cc1cncn1-c1ccc([N+](=O)[O-])cc1C(=O)c1ccccc1Cl>>Cc1cnc(CO)n1-c1ccc([N+](=O)[O-])cc1C(=O)c1ccccc1Cl,,Cc1ccccc1C,,,,test
US20060235222A1,CCC(O)(CC)c1ccc2[nH]ncc2c1.CS(=O)(=O)Nc1cccc2cc[nH]c12>>CCC(CC)(c1ccc2[nH]ncc2c1)c1c[nH]c2c(NS(C)(=O)=O)cccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US05344843,CCOC(=O)C(=O)c1ccc(O)cc1.O=C(CBr)N1CCc2ccccc2C1>>CCOC(=O)C(=O)c1ccc(OCC(=O)N2CCc3ccccc3C2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US05371097,CC(=O)OCC(=O)Cl.NCc1nc(-c2csc(N=C(N)N)n2)cs1>>CC(=O)OCC(=O)NCc1nc(-c2csc(N=C(N)N)n2)cs1,,ClCCl,,CCN(CC)CC,,test
US20080263787A1,CC1=NN(c2ccccn2)C(=O)C1.CN(C)c1ccc(C=O)cc1>>CC1=NN(c2ccccn2)C(=O)/C1=C/c1ccc(N(C)C)cc1,,CCO,O,C1CCNCC1,,test
US20030216571A1,C/C=C/C=O.Nc1cccc(F)c1>>Cc1ccc2c(F)cccc2n1,,O,,Cl,,test
US20140288068A1,BrCC1CC1.Cc1nccc2c1[nH]c1cc(O)ccc12>>Cc1nccc2c1[nH]c1cc(OCC3CC3)ccc12,,CN(C)C=O,,[H-].[Na+],,test
US20150368226A1,CC(C)(C)OC(=O)N1CCC2OC2C1.Fc1ccc2[nH]c3ccc(Cl)cc3c2c1>>CC(C)(C)OC(=O)N1CC[C@@H](n2c3ccc(F)cc3c3cc(Cl)ccc32)[C@H](O)C1,,CN(C)C=O,,,,test
US20060079554A1,CC(C)(C)OC(=O)N1CCCCC1=O.NCc1ccccc1C(F)(F)F>>CC(C)(C)OC(=O)N1CCC(NCc2ccccc2C(F)(F)F)CC1,[Pd],CCO,,,,test
US20110200549A1,BrCC1CC1.CCCCCNC(C)=O>>CCCCCN(CC1CC1)C(C)=O,,COCCOC,,[H-].[Na+],,test
US05654299,O=C(OCc1ccccc1)N1C=CC(c2cccnc2)CC1>>c1cncc(C2CCNCC2)c1,[Pd],CCO,,[H][H],,test
US20160031871A1,CC1CN(C(=O)OC(C)(C)C)CCC1Cc1ccccc1.Cl>>CC1CNCCC1Cc1ccccc1.Cl,,C1COCCO1,,,,test
US20060178373A1,CC(C)(C)N.O=c1cc(-c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)oc2ccc(OCC3CO3)cc12>>CC(C)(C)NCC(O)COc1ccc2oc(-c3ccc(OCc4ccccc4)c(OCc4ccccc4)c3)cc(=O)c2c1,,CO,,,,test
US20070032530A1,FC(F)(F)c1cccc(-c2ccc(CCl)cn2)c1.Oc1ccc(CCCCn2ccnn2)cc1>>FC(F)(F)c1cccc(-c2ccc(COc3ccc(CCCCn4ccnn4)cc3)cn2)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20080261945A1,CN1CCC[C@H]1CO.COC(=O)c1c(CBr)c(-c2ccccc2)nc2ccccc12>>COC(=O)c1c(COC[C@@H]2CCCN2C)c(-c2ccccc2)nc2ccccc12,,CN(C)C=O,,[H-].[Na+],,test
US04228069,CC(=O)OO.COC(C)(C)N=NC(C)(C)C>>COC(C)(C)N=[N+]([O-])C(C)(C)C,,CCOC(C)=O,,,,test
US20100035883A1,CCOC(=O)c1cc(Cl)cc2c1C(=O)C(c1nccn1C)C(c1ccccc1)N2.NN>>Cn1ccnc1C1c2n[nH]c(=O)c3cc(Cl)cc(c23)NC1c1ccccc1,,CO,,O,,test
US20160002266A1,CC(C)(C)OC(=O)N1CCCCC12CC2CNC(=O)c1cc2cnccc2[nH]1.O=C(O)C(F)(F)F>>O=C(NCC1CC12CCCCN2)c1cc2cnccc2[nH]1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20060122263A1,N[C@H]1CC[C@@H](C(c2ccccc2)c2ccccc2)OC1.O=C(O)Cc1ccc(F)cc1>>O=C(Cc1ccc(F)cc1)N[C@H]1CC[C@@H](C(c2ccccc2)c2ccccc2)OC1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20090156559A1,ClCCNCCCl.O=P(Cl)(Cl)Cl>>O=P(Cl)(Cl)N(CCCl)CCCl,,ClCCl,,CCN(CC)CC,Cl,test
US20120190701A1,Cc1c(C(=O)O)cc(Br)cc1C(F)(F)F>>Cc1c(CO)cc(Br)cc1C(F)(F)F,,C1CCOC1,,,,test
US20150031685A1,CC(C)(C)OC(=O)Cc1ccc2c(c1)CS(=O)(=O)N2>>O=C(O)Cc1ccc2c(c1)CS(=O)(=O)N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090264445A1,CC1(C)OC[C@@H](Cn2ccc(NC(=O)[C@H](CC3CCCC3)N3CC(Oc4c(F)cccc4F)=CC3=O)n2)O1>>O=C(Nc1ccn(C[C@@H](O)CO)n1)[C@H](CC1CCCC1)N1CC(Oc2c(F)cccc2F)=CC1=O,,C1CCOC1,CCOC(C)=O,Cl,,test
US03960861,COc1cc2c(cc1OC)CN(c1nc(Cl)nc3cc(OC)c(OC)cc13)CC2.N>>COc1cc2c(cc1OC)CN(c1nc(N)nc3cc(OC)c(OC)cc13)CC2,,CCO,,,,test
US20130274244A1,CCOC(=O)c1cnc2cc(F)ccn12.Cc1nn(Cc2cccc(C(C)C)n2)c2cccc(N)c12>>Cc1nn(Cc2cccc(C(C)C)n2)c2cccc(NC(=O)c3cnc4cc(F)ccn34)c12,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20090281060A1,CC(C)(C)OC(=O)N1CCC(OCC(=O)O)CC1.N=C(NO)c1ccncc1>>CC(C)(C)OC(=O)N1CCC(OCc2nc(-c3ccccn3)no2)CC1,,Cc1ccccc1,,CC(C)COC(=O)Cl,CCN(CC)CC,test
US20080280917A1,Fc1ccc(CCBr)cc1.O=c1ccc(-c2ccccc2)n[nH]1>>O=c1ccc(-c2ccccc2)nn1CCc1ccc(F)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04550107,CN(C)C1CCNCC1.Cl.O=C1Nc2cccnc2N(C(=O)CCl)c2ccccc21>>CN(C)C1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1.Cl,,C1COCCO1,,CCN(CC)CC,,test
US20120225061A1,CSc1cc(F)c(-c2nc(C(=O)[O-])ccc2F)c(F)c1>>CSc1cc(F)c(-c2nc(C(=O)O)ccc2F)c(F)c1,,C1CCOC1,,[Li+].[OH-],,test
US04505905,O=C(OC(c1ccccc1)c1ccccc1)C1=C(Sc2ccccc2)CC2CC(=O)C12>>O=C(O)C1=C(Sc2ccccc2)CC2CC(=O)C12,,O=C(O)C(F)(F)F,,COc1ccccc1,,test
US20110046128A1,CCC(=O)c1ccc(C(F)(F)F)cc1.COP(=O)(O)C(C)(C)C(=O)[O-]>>CCC(=CC(=O)OC)c1ccc(C(F)(F)F)cc1,,[Cl-],[NH4+],C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20060194850A1,COC(=O)c1conc1-c1ccc(C)cc1>>Cc1ccc(-c2nocc2C(=O)O)cc1,,C1CCOC1,,Cl,[Li+].[OH-],test
US20110144105A1,CCOC(=O)C(C)(C)Oc1cnc2[nH]c(C(CC3CCCC3)c3ccc(S(C)(=O)=O)cc3)cc2c1>>CC(C)(Oc1cnc2[nH]c(C(=CC3CCCC3)c3ccc(S(C)(=O)=O)cc3)cc2c1)C(=O)O,,C1CCOC1,O,[Li+].[OH-],,test
US20090149526A1,CN(C)C(=O)CCl.COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(=O)Nc1ccccc1-3>>COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(=O)N(CC(=O)N(C)C)c1ccccc1-3,,CN(C)C=O,,[H-].[Na+],,test
US05756507,Cc1cc(C)cc(-c2[nH]c3ccc(OCc4ccccc4)cc3c2CCN2C(=O)c3ccccc3C2=O)c1>>Cc1cc(C)cc(-c2[nH]c3ccc(O)cc3c2CCN2C(=O)c3ccccc3C2=O)c1,[Pd],CCOC(C)=O,,[H][H],,test
US20120136002A1,CCOC(=O)c1ccc(Oc2ccc(C#N)cc2)nc1Cl.Oc1ccc(OC(F)(F)F)cc1>>CCOC(=O)c1ccc(Oc2ccc(C#N)cc2)nc1Oc1ccc(OC(F)(F)F)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050288314A1,CC(=O)N(C)C.CCOC(C)=O.N#Cc1ccccc1.N=C(N)N.O=C(O)O>>CC(Oc1cccc2nc(N)nc(N)c12)c1ccccn1,,CC(=O)N(C)C,,O,,test
US20140079632A1,O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21.O=C1CCC(=O)N1O>>O=C1N[C@H]2CS[C@@H](CCCCC(=O)ON3C(=O)CCC3=O)[C@H]2N1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20150259354A1,N#Cc1c(-c2ccc(Oc3ccccc3)cc2)nn2c1NCC([N+](=O)[O-])C2>>N#Cc1c(-c2ccc(Oc3ccccc3)cc2)nn2c1NCC(N)C2,[Pd],CO,ClCCl,,,test
US20090088459A1,CS(=O)(=O)c1cccc(B(O)O)c1.O=S(=O)(NCc1ccc(Br)s1)c1cccc(Cl)c1>>CS(=O)(=O)c1cccc(-c2ccc(CNS(=O)(=O)c3cccc(Cl)c3)s2)c1,,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US04118561,CC(=O)c1ccc(CBr)cc1.Nc1nc(N)c2c(ccc3[nH]ccc32)n1>>CC(=O)c1ccc(Cn2ccc3c4c(N)nc(N)nc4ccc32)cc1,,CC(=O)O,CN(C)C=O,[H-].[Na+],O=C([O-])[O-].[K+].[K+],test
US20080090801A1,Cc1nc(-n2c(C)ccc2C)nc2c1ccc(=O)n2N1CCCC1>>Cc1nc(N)nc2c1ccc(=O)n2N1CCCC1,,O,,,,test
US20030236297A1,CC1(CCc2cc(C#CCCCc3ccccc3)cs2)COC(=O)N1>>CC1(CCc2cc(CCCCCc3ccccc3)cs2)COC(=O)N1,[Pd],CCO,,,,test
US06359145B1,CN.COC(=O)c1cn([C@H](CCc2cccc3ccccc23)[C@H](C)O)cn1>>CNC(=O)c1cn([C@H](CCc2cccc3ccccc23)[C@H](C)O)cn1,,C1CCOC1,ClCCl,,,test
US20050032829A1,CC(=O)NC(C)(C)CNc1c(C)c(C)n2nnnc2c1N.CCCC(=O)Cl>>CCCC(=O)Nc1c(NCC(C)(C)NC(C)=O)c(C)c(C)n2nnnc12,,ClCCl,,CCN(CC)CC,,test
US20090137595A1,CCn1nccc1C(=O)O.Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)ccc1F>>CCn1nccc1C(=O)Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)ccc1F,CN(C)C=O,CN1CCCC1=O,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US20130217664A1,CCc1ccc(C(=O)O)cc1N(C)c1cc2c(cn1)ncn2C.COCCN>>CCc1ccc(C(=O)NCCOC)cc1N(C)c1cc2c(cn1)ncn2C,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030144297A1,C(=N/c1ncc[nH]1)\c1ccccc1.CCCI>>CCCn1ccnc1/N=C/c1ccccc1,,CN(C)C=O,O,CC(C)(C)[O-].[K+],,test
US20020068828A1,CCOc1ccc([Sn](C)(C)C)cn1.Fc1cccc(F)c1C1=NC(c2ccc(Br)cc2)CO1>>CCOc1ccc(-c2ccc(C3COC(c4c(F)cccc4F)=N3)cc2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,[Cl-].[Li+],,test
US20060229324A1,CCOC(=O)CC(=O)CC.NNc1ccccc1>>CCC1=NN(c2ccccc2)C(=O)C1,,CCO,,,,test
US20120184542A1,COc1ncc2cc(C(=O)Nc3cc(C(=O)NC(CCCNC(=O)OC(C)(C)C)c4ccccc4)ccc3Cl)c(=O)[nH]c2n1>>COc1ncc2cc(C(=O)Nc3cc(C(=O)NC(CCCN)c4ccccc4)ccc3Cl)c(=O)[nH]c2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150353573A1,COC1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>OC1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,,CC(=O)O,,O=S(=O)(O)O,,test
US20050244332A1,COc1cc(C(O)C(=O)c2ccc3c(c2)C=CC(C)(C)O3)cc(OC)c1OC.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1cc(C(OS(=O)(=O)c2ccc(C)cc2)C(=O)c2ccc3c(c2)C=CC(C)(C)O3)cc(OC)c1OC,,ClCCl,,c1ccncc1,,test
US06191165B1,CCOC(=O)CN(C)CC=C(c1ccccc1)c1cccs1>>CCOC(=O)CN(C)CCC(c1ccccc1)c1cccs1,[Pd],CCO,,,,test
US20140364412A1,CC(C)(C)c1cc(N)n(-c2ccc(Cl)c(O)c2)n1.CC(O)N1CCOCC1>>CC(C)(C)c1cc(N)n(-c2ccc(Cl)c(OCCN3CCOCC3)c2)n1,,C1CCOC1,O,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030069434A1,CN(CCCCC[C@@H]1Cc2cc(O)ccc2[C@H]2[C@@H](F)C[C@]3(C)C(=O)CC[C@H]3[C@H]12)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>CN(CCCCC[C@@H]1Cc2cc(O)ccc2[C@H]2[C@@H](F)C[C@]3(C)[C@@H](O)CC[C@H]3[C@H]12)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F,,CO,,[BH4-].[Na+],,test
US20090069340A1,COc1ccc(Cl)cc1N1CCNCC1.Cn1c(CBr)c(Cl)c(=O)n1C1CCCCC1>>COc1ccc(Cl)cc1N1CCN(Cc2c(Cl)c(=O)n(C3CCCCC3)n2C)CC1,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US05152919,CCCCO[C@@H](C)CC[C@H](C)O.O=C(O)c1ccccc1>>CCCCO[C@@H](C)CC[C@@H](C)OC(=O)c1ccccc1,,CCOCC,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100216802A1,CC(C)(C)OC(=O)N[C@@H](CCBr)C(=O)OC1CCCC1.CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4C5CNCC54)cc3OC)nc2N1C1CCCC1>>CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4C5CN(CC[C@H](NC(=O)OC(C)(C)C)C(=O)OC6CCCC6)CC54)cc3OC)nc2N1C1CCCC1,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US03991076,CN(C)CCN.O=C(CC1CSCCC1=O)c1ccc(Cl)cc1>>CN(C)CCn1c(-c2ccc(Cl)cc2)cc2c1CCSC2,,O,,CC(=O)O,Cl,test
US20130090340A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1c(-c2cccc(F)c2)c(Cl)n2c1CNCC2>>CCOC(=O)c1c(-c2cccc(F)c2)c(Cl)n2c1CN(C(=O)OC(C)(C)C)CC2,,ClCCl,,,,test
US20070244159A1,CC(C)(C(N)=O)c1cc2cc([N+](=O)[O-])ccc2[nH]1>>CC(C)(CN)c1cc2cc([N+](=O)[O-])ccc2[nH]1,,C1CCOC1,,Cl,,test
US20160228450A1,BrCCBr.N#CCc1cccs1>>N#CC1(c2cccs2)CC1,,CS(C)=O,,[H-].[Na+],,test
US20120059007A1,COc1cc(COC(=O)N2CCSC2=S)ccc1OC(C)=O.NCC1CCCCC1>>COc1cc(COC(=O)NCC2CCCCC2)ccc1OC(C)=O,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US20100144710A1,CCCCOc1ccc(CC(=O)O)cc1.CCN=C=NCCCN(C)C.CN(C)C=O.On1nnc2ccccc21>>CCCCOc1ccc(CC(=O)N2CCN(c3ncccc3C#N)CC2)cc1,,CCOC(C)=O,,Cl,O,test
US20070203127A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc2nccc(N3CCC(NCCNC(=O)C(F)(F)F)C3)c2n1>>COc1ccc2nccc(N3CCC(N(CCNC(=O)C(F)(F)F)C(=O)OC(C)(C)C)C3)c2n1,,C1CCOC1,,,,test
US20080058327A1,C[C@@H]1CCc2ncnc(N3CCN(C(=O)[C@@H](Cc4ccc(Cl)cc4)NC(=O)OC(C)(C)C)C[C@@H]3C)c21.Cl.ClCCl>>C[C@@H]1CCc2ncnc(N3CCN(C(=O)[C@H](N)Cc4ccc(Cl)cc4)C[C@@H]3C)c21.Cl.Cl,,ClCCl,,,,test
US20120035214A1,CC(=O)NCCc1ccc(F)cc1-c1ccc([C@@H]2CN(C(=O)OC(C)(C)C)CC[C@H]2c2ccn(C)c(=O)c2)c(Cl)c1>>CC(=O)NCCc1ccc(F)cc1-c1ccc([C@@H]2CNCC[C@H]2c2ccn(C)c(=O)c2)c(Cl)c1,,ClCCl,,C1COCCO1,Cl,test
US04148902,NC(=O)c1c(Cl)cncc1Cl.O=C=Nc1ccc(Cl)cc1>>O=C(NC(=O)c1c(Cl)cncc1Cl)Nc1ccc(Cl)cc1,,Cc1ccccc1C,,,,test
US06511974B1,COC(=O)c1ccc(-c2cnn(C)c2)cc1Cl>>Cn1cc(-c2ccc(C(=O)O)c(Cl)c2)cn1,,CO,,Cl,[Na+].[OH-],test
US20030153752A1,Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)cn2C1CCC(O)C1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)cn2C1CCC(OC(=O)Oc2ccc([N+](=O)[O-])cc2)C1,,ClCCl,,CN1CCOCC1,,test
US20160016966A1,BrP(Br)Br.CC(=O)Nc1cc(-c2cn(C)c(=O)c3cc(CO)oc23)ccn1>>CC(=O)Nc1cc(-c2cn(C)c(=O)c3cc(CBr)oc23)ccn1,,C1COCCO1,ClCCl,,,test
US20030186966A1,CCN1CCN(c2ccc(N)cn2)CC1.O=C(Nc1ccc(Cl)c(C(=O)O)c1)c1ccnc(N2CCOCC2)c1>>CCN1CCN(c2ccc(NC(=O)c3cc(NC(=O)c4ccnc(N5CCOCC5)c4)ccc3Cl)cn2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20060135573A1,COc1cc(N)cc(OC)c1.O=C(Cl)c1c(F)cccc1F>>COc1cc(NC(=O)c2c(F)cccc2F)cc(OC)c1,,Cc1ccccc1,,CCN(CC)CC,,test
US04889869,BrCc1ccccc1.CCOC(=O)CS(C)(=O)=O>>CCOC(=O)C(Cc1ccccc1)S(C)(=O)=O,,CN(C)C=O,,[H-].[Na+],,test
US20140275173A1,BrCC1CCC1.CC(C)(C)OC(=O)COCCC12CCC(c3cccc(O)c3)(CC1)OC2>>O=C(O)COCCC12CCC(c3cccc(OCC4CCC4)c3)(CC1)OC2,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050239781A1,COc1c(Cl)cc2c([nH]c3cnccc32)c1N.Cc1ncncc1C(=O)O>>COc1c(Cl)cc2c([nH]c3cnccc32)c1NC(=O)c1cncnc1C,,O=CO,,,,test
US20160130253A1,O=C1CC(c2ccncc2F)C(c2ccc3ccccc3c2)=NN1>>O=c1cc(-c2ccncc2F)c(-c2ccc3ccccc3c2)n[nH]1,,CS(C)=O,O,O=C1CCC(=O)N1Br,,test
US03983121,C=Cc1ccc2ccccc2n1.c1ccc(N2CCNCC2)cc1>>c1ccc(N2CCN(CCc3ccc4ccccc4n3)CC2)cc1,,CCO,,CC(=O)O,,test
US20070185075A1,CC1(N)CC1.Nc1nc(Cl)cc(Cl)n1>>CC1(Nc2cc(Cl)nc(N)n2)CC1,,CN1CCCC1=O,O,Cl,C[O-].[Na+],test
US20150218107A1,CCOC(=O)/C(C)=C/c1ccc(C(F)(F)F)cc1>>CCOC(=O)C(C)Cc1ccc(C(F)(F)F)cc1,[Pd],CO,,O=O,,test
US04267191,N.NCc1ccco1.S=C=S>>S=C([S-])NCc1ccco1.[NH4+],,CO,,,,test
US20120065196A1,CC(C)c1nnc([C@@H]2CC[C@@H](N)CC2)o1.O=C(NCCNC(=O)c1cn(-c2ccccc2)nc1C(F)(F)F)Oc1ccccc1>>CC(C)c1nnc([C@@H]2CC[C@@H](NC(=O)NCCNC(=O)c3cn(-c4ccccc4)nc3C(F)(F)F)CC2)o1,,CCO,CCOC(C)=O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20140100210A1,O=C([O-])C1CCN(c2ncc(-c3cccc(CO)c3F)cn2)CC1>>O=C(O)C1CCN(c2ncc(-c3cccc(CO)c3F)cn2)CC1,,CCO,,C1CCOC1,[Na+].[OH-],test
US20140371269A1,BrCc1ccccc1.Oc1cccc(Cl)n1>>Clc1cccc(OCc2ccccc2)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100152252A1,C=O.NCCc1cccc(Br)c1>>CNCCc1cccc(Br)c1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20050224415A1,C=CC(=O)O.CCC(N)(O)C(=O)O.CCN=C=NCCCN(C)C>>C=CC(=O)NCCC.CCCNC(C)=O,,O,,,,test
US20040006066A1,CCCC(O)CCC.Cc1cc(C)c(N2CCCc3c2[nH]n(C)c3=O)c(Cl)c1>>CCCC(CCC)Oc1c2c(nn1C)N(c1c(C)cc(C)cc1Cl)CCC2,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04957928,C=CC(=O)OC.NCC1COc2ccc(F)cc2C1>>COC(=O)CCNCC1COc2ccc(F)cc2C1,,CO,,,,test
US05281571,CCOC(=O)CS.Cn1nc(-c2cc(CBr)c(Cl)cc2F)c(Cl)c1C(F)(F)F>>CCOC(=O)CSCc1cc(-c2nn(C)c(C(F)(F)F)c2Cl)c(F)cc1Cl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070078125A1,COC(=O)c1sc(-c2ccc(Cl)cc2)cc1/N=C/N(C)C.Nc1ccc(N2CCOCC2)cc1>>O=c1c2sc(-c3ccc(Cl)cc3)cc2ncn1-c1ccc(N2CCOCC2)cc1,,CCO,,,,test
US20050208582A1,CC(=O)OCC(=O)Cl.NNC(=O)OCc1ccccc1>>CC(=O)OCC(=O)NNC(=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,O,test
US06200998B1,BrCCCBr.COC(=O)Cc1ccc(O)cc1>>COC(=O)Cc1ccc(OCCCBr)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080167303A1,CC(C)N.O=S1(=O)N(CCOCCBr)c2ccccc2N1c1c(F)cccc1F>>CC(C)NCCOCCN1c2ccccc2N(c2c(F)cccc2F)S1(=O)=O,,CO,,,,test
US20010051632A1,CCC(=O)c1ccc(O)cc1.ClCCCBr>>CCC(=O)c1ccc(OCCCCl)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130029962A1,CC(C)(C)c1cc(CNC(=O)Nc2ccc(CO[Si](C)(C)C(C)(C)C)nc2)n(-c2cccc(F)c2)n1>>CC(C)(C)c1cc(CNC(=O)Nc2ccc(CO)nc2)n(-c2cccc(F)c2)n1,,C1CCOC1,,Cl,,test
US20160237095A1,COc1ccc2c(c1)CNC2.Clc1ncc(Cl)c(Nc2ccc3[nH]ncc3c2)n1>>COc1ccc2c(c1)CN(c1ncc(Cl)c(Nc3ccc4[nH]ncc4c3)n1)C2,,CC#N,,CCN(C(C)C)C(C)C,,test
US20100093711A1,CN1c2ccccc2C(=O)C(C)(C)S1(=O)=O>>CN1c2ccccc2C(O)C(C)(C)S1(=O)=O,,CCO,,[BH4-].[Na+],,test
US20110053897A1,CC(C)N.O=c1[nH]ccc2cc(Cl)nc(Cl)c12>>CC(C)Nc1nc(Cl)cc2cc[nH]c(=O)c12,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20120238740A1,C(Cc1ccccc1)=C(C1CCCCC1)C1CCCCC1>>c1ccc(CCC(C2CCCCC2)C2CCCCC2)cc1,[Pd],CCOC(C)=O,,[H][H],,test
US20090062293A1,CC(C)(C)CCC(=O)N1CCN(c2nccc(C#N)n2)CC1.NO>>CC(C)(C)CCC(=O)N1CCN(c2nccc(C(N)=NO)n2)CC1,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080319201A1,CC(C)(C)OC(=O)Nc1cccc2ccc(O)cc12.CCN(CC)CC.CS(=O)(=O)OS(C)(=O)=O.ClCCl>>S=C=Nc1ccc(C2CC2)c2ccccc12,,ClCCl,,O=C([O-])O.[Na+],,test
US20100305084A1,O=C1COC2(CCN(Cc3cc4nc(Cl)nc(N5CCOCC5)c4s3)CC2)CN1.O=S(=O)(c1ccccc1)n1cc(B(O)O)c2ccccc21>>O=C1COC2(CCN(Cc3cc4nc(-c5cn(S(=O)(=O)c6ccccc6)c6ccccc56)nc(N5CCOCC5)c4s3)CC2)CN1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040092525A1,Cc1ccc(N)c(C)c1.O=[N+]([O-])O>>Cc1cc(C)c([N+](=O)[O-])cc1N,,O=S(=O)(O)O,,,,test
US20160122302A1,Cc1cc(CCc2cccc(C(O)Cc3cc(C)cc(-n4c(C)ccc4C)n3)c2)nc(-n2c(C)ccc2C)c1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cc1cc(CCc2cccc(C(Cc3cc(C)cc(-n4c(C)ccc4C)n3)N=[N+]=[N-])c2)nc(-n2c(C)ccc2C)c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110212046A1,CI.OCC1CC=CCC1>>COCC1CC=CCC1,,C1CCOC1,O,[H-].[Na+],,test
US20150210659A1,CCOC(=O)CN1CCN(Cc2ccc(F)cc2)CC1.NN>>NNC(=O)CN1CCN(Cc2ccc(F)cc2)CC1,,CCO,,,,test
US20100298325A1,COc1cc(N)ccc1F.Fc1cc(Oc2cccc(N3CCCC3)c2)cnc1Cl>>COc1cc(Nc2ncc(Oc3cccc(N4CCCC4)c3)cc2F)ccc1F,,C1COCCO1,CCOC(C)=O,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20100249089A1,C1COCCN1.COc1ccc(/C(C#N)=C/c2ccc(N3CCC(OC(=O)CN4CCC(O)CC4)CC3)s2)cc1OC>>COc1ccc(/C(C#N)=C/c2ccc(N3CCC(OC(=O)CN4CCOCC4)CC3)s2)cc1OC,,CCN(CC)CC,,,,test
US20060063785A1,Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1.O=C(Cl)OCC(Cl)(Cl)Cl>>O=C(Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1)OCC(Cl)(Cl)Cl,,C1CCOC1,,CCN(CC)CC,,test
US20090036453A1,C[Si](C)(C)CCOCn1ncc2c(c(Cc3ccccc3)c(-c3ccc(OC(F)F)c(OC4CC4)c3)n2COCc2ccccc2)c1=O>>O=c1[nH]ncc2c1c(Cc1ccccc1)c(-c1ccc(OC(F)F)c(OC3CC3)c1)n2COCc1ccccc1,,C1COCCO1,,Cl,,test
US20120190677A1,CCc1ccc(N2CCOCC2)cc1C1CC(C)(C)c2cc(C(=O)O)ccc2N1.NS(=O)(=O)C1CC1>>CCc1ccc(N2CCOCC2)cc1C1CC(C)(C)c2cc(C(=O)NS(=O)(=O)C3CC3)ccc2N1,,CN(C)C=O,O,O=C(n1ccnc1)n1ccnc1,[H-].[Na+],test
US20060199795A1,CC(=O)OC(C)=O.CC(C)(C)CN1C(=O)C(CC(=O)NCc2ccccc2F)N(C(=O)c2ccncc2)Cc2ccccc21>>CC(=O)N1Cc2ccccc2N(CC(C)(C)C)C(=O)C1CC(=O)NCc1ccccc1F,CN(C)c1ccncc1,c1ccncc1,,,,test
US20130172310A1,Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1>>O=CNc1ccc(Cl)cn1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,c1ccncc1,test
US04861785,BrCCCCCCBr.Oc1cccc(F)c1>>Fc1cccc(OCCCCCCBr)c1,,O,,[Na+].[OH-],,test
US20080076763A1,CC(C)(C)OC(=O)N1CCOC(COC(=O)c2ccccc2)C1>>CC(C)(C)OC(=O)N1CCOC(CO)C1,,CO,,[Na+].[OH-],,test
US20050256103A1,O=C(O)c1ccc2ccn(C3CCN(C(=O)OCc4ccccc4)CC3)c2c1.[NH4+]>>NC(=O)c1ccc2ccn(C3CCN(C(=O)OCc4ccccc4)CC3)c2c1,,C1CCOC1,,O,O=C(n1ccnc1)n1ccnc1,test
US04614740,COc1cc2c(cc1OC)C(c1ccc([N+](=O)[O-])cc1)=NN=C(C)C2>>COc1cc2c(cc1OC)C(c1ccc(N)cc1)=NN=C(C)C2,[Pd],CN(C)C=O,,,,test
US20160264548A1,CC(C)(C)NC(=O)c1ccc(Nc2nc(Cl)ncc2C#N)cc1.CC(C)(C)OC(=O)N[C@H]1CCNC1>>CC(C)(C)NC(=O)c1ccc(Nc2nc(N3CC[C@H](NC(=O)OC(C)(C)C)C3)ncc2C#N)cc1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,,test
US20100029621A1,CC(C)(C)CC(=O)Cl.Nc1ccc(C(=O)N2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1F>>CC(C)(C)CC(=O)Nc1ccc(C(=O)N2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1F,,ClCCl,,CCN(CC)CC,,test
US20150045426A1,COCOC1=C(O)C(=O)OC1C1COC(C)(C)O1>>O=C1O[C@H]([C@@H](O)CO)C(O)=C1O,,C1CCOC1,,,,test
US04873232,CC=Cc1cccc2nc(OCC)oc(=O)c12.[OH-]>>CC=Cc1cccc(NC(=O)OCC)c1C(=O)O,,[Na+],[OH-],C1CCOC1,,test
US20090192145A1,CCOC(=O)CBr.N#Cc1ccc2c(c1)CCCC2(O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>CCOC(=O)COC1(c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)CCCc2cc(C#N)ccc21,,C1CCOC1,,[H-].[Na+],,test
US05565477,Nc1ccc(C(=O)c2ccccc2)cc1.O=C(O)C(O)(C(F)(F)F)C(F)(F)F>>O=C(c1ccccc1)c1ccc(NC(=O)C(O)(C(F)(F)F)C(F)(F)F)cc1,,C1CCOC1,,O=C=O,,test
US20090221555A1,CI.O=C1CCCc2cc([N+](=O)[O-])ccc2N1>>CN1C(=O)CCCc2cc([N+](=O)[O-])ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20160046624A1,Cn1c(=O)n(CCCOC2CCCCO2)c(=O)c2cc(Br)cnc21.O=Cc1ccc(Cl)cc1>>Cn1c(=O)n(CCCOC2CCCCO2)c(=O)c2c(C(O)c3ccc(Cl)cc3)c(Br)cnc21,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20040236104A1,CN(C)C1(c2ccccc2)CCC(=O)CC1.c1ccc2sccc2c1>>CN(C)C1(c2ccccc2)CCC(O)(c2cc3ccccc3s2)CC1,,C1CCOC1,,CCCCC,[Li]C(C)(C)C,test
US20050187390A1,CC(=O)c1cc2cccc(O)c2o1.O=C(O)c1ccc2c(c1)nc(-c1ccc3nc(-c4cc(Br)ccc4O)ccc3c1)n2C1CCCCC1>>O=C(O)c1ccc2c(c1)nc(-c1ccc3nc(-c4cc5cccc(O)c5o4)ccc3c1)n2C1CCCCC1,,CCO,,[K+].[OH-],,test
US20100273739A1,COc1ccc2c(c1)C(Cc1cccc(Cl)c1)C(N1CCCC1)CC2>>Oc1ccc2c(c1)C(Cc1cccc(Cl)c1)C(N1CCCC1)CC2,,ClCCl,,[Na+].[OH-],,test
US20130072495A1,CC1(C)OB(c2cnn(C3CCNCC3)c2)OC1(C)C.O=CO>>CC1(C)OB(c2cnn(C3CCN(C=O)CC3)c2)OC1(C)C,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US04673686,C#CCBr.COC(=O)c1cc(Cl)cc(Cl)c1O>>C#CCOc1c(Cl)cc(Cl)cc1C(=O)OC,,CCC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20090012263A1,Nc1ccc2c(ccn2Cc2c(Cl)cccc2Cl)c1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ccc2c(ccn2Cc2c(Cl)cccc2Cl)c1)Oc1ccccc1,,ClCCl,O,CN(C)c1ccccc1,,test
US20160016914A1,COC(=O)c1cnn2c(C#N)c(OCc3ccccc3)ccc12>>COC(=O)c1cnn2c(C#N)c(O)ccc12,[Pd],C1CCOC1,CO,,,test
US20070219187A1,CC(C)(C)OC(=O)N1CCC[C@H](C(=O)Nc2ccc(F)cc2)C1.Cl>>Cl.O=C(Nc1ccc(F)cc1)[C@H]1CCCNC1,,ClCCl,,,,test
US20070167433A1,C=CCOc1ccc([C@@H]2[C@@H](OCc3ccc4c(c3)N(CCCOC)C(=O)CO4)CN(C(=O)OCc3ccccc3)C[C@H]2O[Si](C(C)C)(C(C)C)C(C)C)cc1>>COCCCN1C(=O)COc2ccc(CO[C@H]3CN(C(=O)OCc4ccccc4)C[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]3c3ccc(O)cc3)cc21,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20140315889A1,CNCCO.COC(=O)c1ccc(Cn2c3c(c4cc(F)ccc42)C(=O)N(CCO)CC3)cc1>>COC(=O)c1ccc(Cn2c3c(c4cc(F)ccc42)C(=O)N(CCN(C)CCO)CC3)cc1,,CC#N,,CCN(C(C)C)C(C)C,CS(=O)(=O)Cl,test
US20090018132A1,CC(C)(C)OC(=O)N1CCC(COCc2cc(C(F)(F)F)cc3c2nnn3COCC[Si](C)(C)C)(c2ccc(F)cc2)CC1>>Fc1ccc(C2(COCc3cc(C(F)(F)F)cc4nn[nH]c34)CCNCC2)cc1,,O=C(O)C(F)(F)F,,,,test
US20150018356A1,CCOC(=O)c1cccc(N)c1C(=O)OCC.COC(=O)c1cccc(N)c1C(=O)OC.O=C1CCc2ccccc2C1>>O=C(O)c1cccc2[nH]c3c(c(=O)c12)-c1ccccc1CC3,,CO,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20050176759A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)[Si](C)(C)Oc1cccc(S(=O)(=O)c2ccc3c(c2)CCNCC3)c1>>CC(C)(C)OC(=O)N1CCc2ccc(S(=O)(=O)c3cccc(O[Si](C)(C)C(C)(C)C)c3)cc2CC1,,ClCCl,,,,test
US20010051633A1,OO.c1ccc(Cc2ccncc2)cc1>>[O-][n+]1ccc(Cc2ccccc2)cc1,,O=C([O-])O,[Na+],CC(=O)O,,test
US05559106,CCOC(=O)C(=O)NNc1nc2ccc([N+](=O)[O-])cc2nc1Cl>>CCOC(=O)c1nnc2c(Cl)nc3cc([N+](=O)[O-])ccc3n12,,O=P(Cl)(Cl)Cl,,,,test
US20040102479A1,COCOc1ccc(C2(C)CSc3cc(OCOC)ccc3C2CCCOc2ccc(OCCO)cc2)cc1.CS(=O)(=O)Cl>>COCOc1ccc(C2(C)CSc3cc(OCOC)ccc3C2CCCOc2ccc(OCCOS(C)(=O)=O)cc2)cc1,,ClCCl,,CCN(CC)CC,[Cl-].[NH4+],test
US06043248,CC(O)c1cc(C(C)(C)C)ccn1.O=S(Cl)Cl>>CC(Cl)c1cc(C(C)(C)C)ccn1,,ClCCl,,,,test
US04870073,COC(=O)CS.O=[N+]([O-])c1ccccc1CCl>>COC(=O)CSCc1ccccc1[N+](=O)[O-],,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110118248A1,CC(C)(O)c1cc(S(=O)(=O)Nc2cc(Cl)cnc2Br)ccc1Cl.COCCl>>COCN(c1cc(Cl)cnc1Br)S(=O)(=O)c1ccc(Cl)c(C(C)(C)O)c1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20110207702A1,COCCl.OCc1ccc(Sc2ccc(Cl)cc2)cc1Br>>COCOCc1ccc(Sc2ccc(Cl)cc2)cc1Br,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05488061,CCCCCCCCC#Cc1ccc2sccc2c1.CN(C)C=O>>CCCCCCCCC#Cc1ccc2sc(C=O)cc2c1,,CCOCC,,[Li]CCCC,,test
US06683096B2,COC(=O)c1cccc(CBr)c1.c1ccc2c(c1)c(C1CCNCC1)cn2CC1CC1>>O=C(O)c1cccc(CN2CCC(c3cn(CC4CC4)c4ccccc34)CC2)c1,,CC(=O)CC(C)C,,[I-].[K+],,test
US20090143361A1,COc1ccc(Cl)cc1B(O)O.COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)cc(Cl)c4)n3c2n1>>COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)ccc4OC)n3c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20070167433A1,BrB(Br)Br.COc1ccc([C@@H]2[C@@H](COC(c3ccccc3)(c3ccccc3)c3ccccc3)CN(Cc3ccccc3)C[C@H]2O)cc1>>Br.OC[C@H]1CN(Cc2ccccc2)C[C@@H](O)[C@@H]1c1ccc(O)cc1,,ClCCl,,,,test
US20100048636A1,COC(=O)NCCO[C@@H](c1ccccc1)[C@@H]1CCCN(C(=O)N[C@@H](CC2CCOCC2)CN(C)C(=O)OCC[Si](C)(C)C)C1>>CNC[C@H](CC1CCOCC1)NC(=O)N1CCC[C@@H]([C@@H](OCCNC(=O)OC)c2ccccc2)C1,,CC#N,,CCN(CC)CC,O=CO,test
US20090075989A1,Cc1noc(=O)c2ccc(N)cc12.O=C(O)C(=O)c1cccnc1>>Cc1noc(=O)c2ccc(NC(=O)C(=O)c3cccnc3)cc12,,CC(=O)N(C)C,,O=S(Cl)Cl,,test
US20070191420A1,O=C(NC[C@@H]1CC[C@@H](C(=O)NCc2ccncc2)CC1)OCc1ccccc1>>NC[C@@H]1CC[C@@H](C(=O)NCc2ccncc2)CC1,[Pd],CO,,O=C[O-].[NH4+],,test
US20110224305A1,CC(C)CC(N)C1(c2ccc(Cl)cc2)CCC1.CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)O>>CCC(C)C(NC(=O)OC(C)(C)C)C(=O)NC(CC(C)C)C1(c2ccc(Cl)cc2)CCC1,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20100173888A1,CC(C)(C)OC(=O)NC1CCC(c2ncc[nH]2)CC1>>NC1CCC(c2ncc[nH]2)CC1,,C1COCCO1,Cl,,,test
US06399643B1,Cc1ccccc1N=C=O.O=[N+]([O-])c1ccc(CO)cc1>>Cc1ccccc1NC(=O)Nc1ccc(CO)cc1,[Pd],COC(C)(C)C,,,,test
US04182897,CC(Cc1cccc(N)c1)C(=O)Oc1ccccc1.Cl.N#CN>>CC(Cc1cccc(NC(=N)N)c1)C(=O)Oc1ccccc1.Cl,,CCO,,,,test
US04560692,CC(=O)c1ccc(F)cc1.O=C1Nc2ccccc2C1=O>>O=C(O)c1cc(-c2ccc(F)cc2)nc2ccccc12,,CCO,,Cl,[Na+].[OH-],test
US04588733,Clc1ccc(C2C=Cc3cc(Br)cnc3O2)cc1Cl>>Clc1ccc(C2=CCc3cc(Br)cnc3O2)cc1Cl,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20020128292A1,Cc1ccc(C=NNC(=O)c2[nH]c3ccc(Cl)cc3c2C)cc1>>Cc1ccc(CNNC(=O)c2[nH]c3ccc(Cl)cc3c2C)cc1,,CO,O,[BH4-].[Na+],,test
US20030153568A1,CCNC(=O)Nc1nc2ccc(C#Cc3ccccc3)cc2s1>>CCNC(=O)Nc1nc2ccc(CCc3ccccc3)cc2s1,[Pd],CCO,,,,test
US20100216638A1,CC(C)(C)C(=O)Cl.Cc1cc(-c2ccccc2)cc(C)c1C1C(=O)C2CCC(C2)C1=O>>Cc1cc(-c2ccccc2)cc(C)c1C1=C(OC(=O)C(C)(C)C)C2CCC(C2)C1=O,,ClCCl,,CCN(CC)CC,,test
US20030134849A1,CCCc1ccc(-c2ccc([C@@]3(CC(=O)OC(C)(C)C)CCN(C(=O)OC(C)(C)C)CCS3(=O)=O)s2)cc1>>CCCc1ccc(-c2ccc([C@@]3(CC(=O)OC(C)(C)C)CCNCCS3(=O)=O)s2)cc1,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20040176426A1,Cc1ccc(C)c(NS(=O)(=O)c2ccccc2[N+](=O)[O-])c1>>Cc1ccc(C)c(NS(=O)(=O)c2ccccc2N)c1,,CCOC(C)=O,,[K+].[OH-],,test
US04223033,CC(C)C(C(=O)O)c1ccc2ccccc2c1.OCc1cccc(Oc2ccccc2)n1>>CC(C)C(C(=O)OCc1cccc(Oc2ccccc2)n1)c1ccc2ccccc2c1,,CCOCC,,CCN(CC)CC,,test
US20120101083A1,CC(C)(C)OC(=O)N1CCc2ccc(C(=N)NO)cc2CC1.CC(C)Oc1ncc(C(=O)Cl)cc1C#N>>CC(C)Oc1ncc(-c2nc(-c3ccc4c(c3)CCN(C(=O)OC(C)(C)C)CC4)no2)cc1C#N,,Cc1ccccc1,c1ccncc1,,,test
US20130053407A1,CN.COc1cccc(-c2ccc(-n3c(Cl)cc4[nH]c(=O)n(CCC(=O)O)c(=O)c43)cc2)c1O>>CNC(=O)CCn1c(=O)[nH]c2cc(Cl)n(-c3ccc(-c4cccc(OC)c4O)cc3)c2c1=O,,C1CCOC1,ClCCl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20120172366A1,CC(C)(C)OC(=O)N1CCn2c(Cl)cnc2C1>>Clc1cnc2n1CCNC2,,C1COCCO1,,Cl,,test
US20100063037A1,CN1CCNCC1CO.COc1cccc2c1C(NC1=Nc3ccc(NC(=O)CCl)cc3CO1)CC2>>COc1cccc2c1C(NC1=Nc3ccc(NC(=O)CN4CCN(C)C(CO)C4)cc3CO1)CC2,,CC#N,,CCN(C(C)C)C(C)C,,test
US20100197683A1,C[Mg]Br.N#Cc1ccccc1-c1ccc(C=O)cc1>>CC(O)c1ccc(-c2ccccc2C#N)cc1,,C1CCOC1,,Cl,,test
US20130078570A1,O=S(=O)(Cl)c1ccc(O)cc1.[N-]=[N+]=[N-]>>[N-]=[N+]=NS(=O)(=O)c1ccc(O)cc1,,CC(C)=O,,O,,test
US20150133512A1,CC(O)C1CC1.Cc1nnn(-c2ccc(Br)cc2)c1C(=O)O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cc1nnn(-c2ccc(Br)cc2)c1NC(=O)OC(C)C1CC1,,Cc1ccccc1,,CCN(CC)CC,,test
US05721230,N.O=C(O)C1CCn2c(cc3ccccc32)C1>>NC(=O)C1CCn2c(cc3ccccc32)C1,,CC(C)=O,O,CCN(CC)CC,CCOC(=O)Cl,test
US04654343,COC(=O)Cl.Cc1nnc2ccc(-c3cccc(N)c3)nn12>>COC(=O)Nc1cccc(-c2ccc3nnc(C)n3n2)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150322043A1,N#Cc1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1.OO>>NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150376225A1,C[C@]12CCC(=O)C=C1CC[C@H]1[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]12>>CC12CCC(=O)C=C1CCC1C2C(O)CC2(C)C1CCC2(O)C(O)CO,,C1CCOC1,O,[BH4-].[Na+],,test
US20080255202A1,COc1ccc(C=O)c(C)c1.NO>>COc1ccc(C=NO)c(C)c1,,CO,O,Cl,O=C([O-])O.[Na+],test
US20140088075A1,CNc1cc2c(cn1)cc(-c1cc(N)c(F)cc1Br)c(=O)n2C.O=C=Nc1ccccc1>>CNc1cc2c(cn1)cc(-c1cc(NC(=O)Nc3ccccc3)c(F)cc1Br)c(=O)n2C,,ClCCl,,,,test
US20080207891A1,CC(C)c1nccn1-c1nc(Cl)nc2nc[nH]c12.Cc1ccc(C(=O)OC[C@H]2O[C@H](Cl)C[C@@H]2OC(=O)c2ccc(C)cc2)cc1>>Cc1ccc(C(=O)OC[C@H]2O[C@@H](n3cnc4c(-n5ccnc5C(C)C)nc(Cl)nc43)C[C@@H]2OC(=O)c2ccc(C)cc2)cc1,,CC#N,ClCCl,[Na],,test
US20060052426A1,N[C@@H](Cc1ccccc1)C(=O)O.O=S(=O)(O)O>>O=C(O)C(O)Cc1ccccc1,,O,O=S(=O)(O)O,O=N[O-].[Na+],,test
US05035736,Cl.N#Cc1c(NC(=O)c2ccccc2)ccc2ccccc12>>N#Cc1c(Cl)ccc2ccccc12,Cl[Cu]Cl,CC#N,,,,test
US20120294835A1,COc1cccc(N)c1.Clc1cc(Cl)ncn1.NC1CCCCC1>>COc1cccc(Nc2cc(NC3CCCCC3)ncn2)c1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20060148800A1,CC(C)(C)OC(=O)NC1CC(O)C1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)C2CC(NC(=O)OC(C)(C)C)C2)cc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20030096826A1,CCOC(=O)N=NC(=O)OCC.CON(C)C(=O)[C@H](CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccccc1O.OCCc1cncc2ccccc12.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CON(C)C(=O)[C@H](CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccccc1OCCc1cncc2ccccc12.O=P(c1ccccc1)(c1ccccc1)c1ccccc1,,C1CCOC1,,,,test
US20100099695A1,CS(=O)(=O)Cl.OCc1cc(Br)ccc1Cl>>CS(=O)(=O)OCc1cc(Br)ccc1Cl,,ClCCl,,,,test
US06495551B1,CC(=O)NC[C@H]1CN(c2ccc(-n3cnc(C(=O)Nc4cccc(N)n4)c3)c(F)c2)C(=O)O1.CC(=O)OC(C)=O>>CC(=O)NC[C@H]1CN(c2ccc(-n3cnc(C(=O)Nc4cccc(NC(C)=O)n4)c3)c(F)c2)C(=O)O1,,c1ccncc1,,,,test
US04670447,NN.O=C(c1ccccc1F)C1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1>>Fc1ccc(C(CCCN2CCC(c3n[nH]c4ccccc34)CC2)c2ccc(F)cc2)cc1,,O,,,,test
US04581168,CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)ON1C(=O)CCC1=O.CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCSC)C(=O)NNC(=O)OCC(Cl)(Cl)Cl>>CC[C@H](C)[C@H](NC(=O)[C@H](CC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCSC)C(=O)NNC(=O)OCC(Cl)(Cl)Cl,,C1CCOC1,CCOC(C)=O,,,test
US20080207609A1,CC(C)(C)OC(=O)NC1CCN(Cc2cc3nc(-c4cccc(O[Si](C)(C)C(C)(C)C)c4)nc(N4CCOCC4)c3s2)CC1>>CC(C)(C)OC(=O)NC1CCN(Cc2cc3nc(-c4cccc(O)c4)nc(N4CCOCC4)c3s2)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140256941A1,CC1(C)OB(c2cnn(C3(CC#N)CN(C4CCN(C(=O)c5ccnc(C(F)(F)F)c5F)CC4)C3)c2)OC1(C)C.Clc1ncnc2[nH]ccc12>>N#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(C2CCN(C(=O)c3ccnc(C(F)(F)F)c3F)CC2)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])O.[Na+],test
US20150152108A1,Cc1cc(-c2ccc3c(n2)N[C@H]2CCN3C2)ccn1.Cn1cc2cc(NC(=O)Oc3ccccc3)ccc2n1>>Cc1cc(-c2ccc3c(n2)N(C(=O)Nc2ccc4nn(C)cc4c2)[C@H]2CCN3C2)ccn1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20060122256A1,COC(=O)c1cccc(COc2ccc(I)cc2)c1.OB(O)c1cccc2cnccc12>>O=C(O)c1cccc(COc2ccc(-c3cccc4cnccc34)cc2)c1,,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20060052392A1,O=C(O)c1cc2c(cc1C(=O)O)CCC2>>O=C1OC(=O)c2cc3c(cc21)CCC3,,CC(=O)OC(C)=O,,,,test
US05171851,Cc1cn(-c2ccc([N+](=O)[O-])c(C)c2)cn1>>Cc1cn(-c2ccc(N)c(C)c2)cn1,[Pd],CO,,[H][H],,test
US20060052600A1,COc1ccc(C(C)(C)C#N)cc1.O=C1CCC(=O)N1Br>>COc1ccc(C(C)(C)C#N)cc1Br,,O=C(O)C(F)(F)F,,,,test
US20140296519A1,O=[N+]([O-])c1cccc(Cl)c1Cl.OB(O)Oc1ccccc1>>O=[N+]([O-])c1cccc(Cl)c1-c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140364432A1,Cc1nc(C(=O)N2CCC[C@@H](C)[C@H]2CN)c(-c2ccccc2)s1.Clc1nc2ccccc2o1>>Cc1nc(C(=O)N2CCC[C@@H](C)[C@H]2CNc2nc3ccccc3o2)c(-c2ccccc2)s1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20020052364A1,CNC(=O)N1N=C(c2ccc([N+](=O)[O-])cc2)c2cc3c(cc2CC1CO)OCO3>>CNC(=O)N1N=C(c2ccc(N)cc2)c2cc3c(cc2CC1CO)OCO3,[Ni],CCO,,NN,O,test
US20030069257A1,Cc1ncc2nc(CCl)n(C)c2n1.Fc1cccc(-c2ncc[nH]2)n1>>Cc1ncc2nc(Cn3ccnc3-c3cccc(F)n3)n(C)c2n1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05380834,CO.O=C1C(CO)=C[C@H]2CO[C@@H]1O2>>COCC1=C[C@H]2CO[C@H](O2)C1=O,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20140057893A1,N#CN1CCC([C@H]2C[C@H]2CCO)CC1.NO>>N=C(NO)N1CCC([C@H]2C[C@H]2CCO)CC1,,CCO,,,,test
US20100240688A1,O=c1c(Cl)c(OCc2ccccc2)ccn1Cc1ccc(OC(F)(F)F)cc1>>O=c1c(Cl)c(O)ccn1Cc1ccc(OC(F)(F)F)cc1,,CC(=O)O,,Br,,test
US20150065464A1,O=[N+]([O-])c1cccc(C=C2CCC3(CC2)OCCO3)c1>>O=C1CCC(=Cc2cccc([N+](=O)[O-])c2)CC1,,CC(C)=O,,Cl,,test
US20040102634A1,CCOC(=O)C(Cc1cccc(N)c1)OC(C)C.O=C1OCCC1Oc1ccc(Cl)cc1Cl>>CC(C)OC(Cc1cccc(NC(=O)C(CCO)Oc2ccc(Cl)cc2Cl)c1)C(=O)O,,Cc1ccccc1,,,,test
US20050256210A1,C1=C(c2ccccc2)CCCC1.Oc1ccccc1>>Oc1ccc(C2(c3ccccc3)CCCCC2)cc1,,ClCCl,,,,test
US20110269773A1,CC(C)(C)OC(=O)N1CCNCC1.CC1OCc2ncnc(Cl)c21>>CC1OCc2ncnc(N3CCN(C(=O)OC(C)(C)C)CC3)c21,,CCOC(C)=O,O,CN1CCCC1=O,,test
US20090318410A1,CC(=O)CCl.COc1ccc(-c2ccc(N)nn2)cc1OC>>COc1ccc(-c2ccc3nc(C)cn3n2)cc1OC,,CCO,,CCN(CC)CC,,test
US03959322,CCN(CC)CC#CCCCc1ccccc1.O>>CCN(CC)CCC(=O)CCCc1ccccc1,,O,O=S(=O)(O)O,[Na+].[OH-],,test
US20080146565A1,CCCCS(=O)(=O)c1nccc(-n2cc(C(N)=O)c3ccccc32)n1.CCOC(=O)C1CCC(N)CC1>>CCOC(=O)C1CCC(Nc2nccc(-n3cc(C(N)=O)c4ccccc43)n2)CC1,,C1COCCO1,,,,test
US20090163508A1,Cc1noc(NC(=O)OCC(Cl)(Cl)Cl)c1C.Fc1ccccc1-c1ccnc(N2CCNCC2)n1>>Cc1noc(NC(=O)N2CCN(c3nccc(-c4ccccc4F)n3)CC2)c1C,,C1CCOC1,CCCCCC,Cl,Cl,test
US20040082573A1,CCOC(=O)c1ncn2c1CN=C(c1ccccc1)c1cc(Br)ccc1-2>>O=C(O)c1ncn2c1CN=C(c1ccccc1)c1cc(Br)ccc1-2,,CCO,,[Na+].[OH-],,test
US20070213315A1,CC(=O)N[C@H]1CCC2(CCNCC2)c2ccccc21.CC(C)(C)C(=O)CBr>>CC(=O)N[C@H]1CCC2(CCN(CC(=O)C(C)(C)C)CC2)c2ccccc21,,CN(C)C=O,,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],test
US20020072514A1,CCCCI.CCS(=O)(=O)NC1CCCOc2c(C)cc(Cl)cc21>>CCCCN(C1CCCOc2c(C)cc(Cl)cc21)S(=O)(=O)CC,,CN(C)C=O,,[H-].[Na+],,test
US20130217702A1,CC(C)OB(OC(C)C)OC(C)C.C[C@@H](NC(=O)OC(C)(C)C)c1ccc(Br)cc1>>C[C@@H](NC(=O)OC(C)(C)C)c1ccc(B(O)O)cc1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20090292024A1,COC(=O)c1ccc(O)cc1F.O=S(=O)(OCCC(F)(F)F)C(F)(F)F>>O=C(O)c1ccc(OCCC(F)(F)F)cc1F,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110040115A1,COc1ccc(B2OB(c3ccc(OC)c(C45CC6CC(CC(C6)C4)C5)c3)OB(c3ccc(OC)c(C45CC6CC(CC(C6)C4)C5)c3)O2)cc1C12CC3CC(CC(C3)C1)C2.Oc1ccc2cc(Br)ccc2c1>>COc1ccc(-c2ccc3cc(O)ccc3c2)cc1C12CC3CC(CC(C3)C1)C2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,O,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US03985746,N#CCCC(=S)Cl.NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(O)CS[C@H]12>>N#CCCC(=S)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(O)CS[C@H]12,,ClCCl,,CCN(CC)CC,Cc1ccc(S(=O)(=O)O)cc1,test
US20110021520A1,C[C@@](O)(CN=[N+]=[N-])c1cc(Br)ccc1F>>C[C@@](O)(CN)c1cc(Br)ccc1F,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110269738A1,CC(C)Br.Oc1ccc(Br)cc1Cl>>CC(C)Oc1ccc(Br)cc1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100190794A1,CCOC(=O)CNCC(=O)OC(C)(C)C.C[Si](C)(C)Cl.O=Cc1ccccc1[N+](=O)[O-]>>CCOC(=O)C(NCC(=O)OC(C)(C)C)C(O[Si](C)(C)C)c1ccccc1[N+](=O)[O-],,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20060264415A1,NC(N)=S.O=C(CBr)CCCCCNC(=O)COCc1ccc(F)cc1>>Nc1nc(CCCCCNC(=O)COCc2ccc(F)cc2)cs1,,CCO,,,,test
US20080039476A1,CC1NCCc2sccc21.O=C(O)c1cc2ncc(Br)cn2n1>>CC1c2ccsc2CCN1C(=O)c1cc2ncc(Br)cn2n1,,CC#N,O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20060106075A1,O=C(CN(CCc1ccc(OCCCCc2ccccc2)cc1)Cc1ccccc1)c1ccc(O)c2[nH]c(=O)sc12>>O=c1[nH]c2c(O)ccc(C(O)CN(CCc3ccc(OCCCCc4ccccc4)cc3)Cc3ccccc3)c2s1,,CO,,[BH4-].[Na+],,test
US05646173,CCC1(CC)c2ccc(OC)cc2C(=O)C1CC=O.C[C@@H](O)CN>>CCC1(CC)c2ccc(OC)cc2-c2c1ccn2C[C@@H](C)O,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,O,,test
US20100249118A1,OC(c1ccc(OCc2ccc(Cl)cc2)c(F)c1)c1c[nH]c2ncccc12>>O=C(c1ccc(OCc2ccc(Cl)cc2)c(F)c1)c1c[nH]c2ncccc12,,C1CCOC1,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US03937730,CCC1CCCC(C)C1=NC(C)COC.O=C(Cl)CCl>>CCC1=C(N(C(=O)CCl)C(C)COC)C(C)CCC1,,c1ccccc1,,CCN(CC)CC,,test
US20100256156A1,CCOC(=O)c1cc(C(O)(CC)CC)sc1CC>>CCOC(=O)c1cc(C(CC)CC)sc1CC,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20150329549A1,Cc1c(C(=O)O)nnn1-c1ccc(C2CC2)cc1Cl.Cc1c(N)c(=O)n(C2CCCCC2)n1C>>Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)nnn1-c1ccc(C2CC2)cc1Cl,,CCOC(C)=O,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US20130157977A1,Cc1c(Cl)cccc1CBr.O=[N+]([O-])c1cc(Br)c2nc(C(F)F)[nH]c2c1>>Cc1c(Cl)cccc1Cn1c(C(F)F)nc2c(Br)cc([N+](=O)[O-])cc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120316170A1,CON(C)C(C)=O.Cc1c(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)ncn1COCC[Si](C)(C)C>>CC(=O)c1nc(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(C)n1COCC[Si](C)(C)C,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20090181942A1,C=CCBr.COC(=O)C(C)(C)O>>C=CCOC(C)(C)C(=O)OC,,CN(C)C=O,,O,[H-].[Na+],test
US20160096827A1,COc1cc(Nc2ncnc(-c3ccc(O[C@H]4CCNC[C@H]4F)c(C#N)c3)n2)ccc1N1CCN(C2COC2)CC1.N#CCC(=O)O>>COc1cc(Nc2ncnc(-c3ccc(O[C@H]4CCN(C(=O)CC#N)C[C@H]4F)c(C#N)c3)n2)ccc1N1CCN(C2COC2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090286807A1,CC[C@H](C[C@H](O)[C@@H](N)CN1CC(=O)N(c2ccccc2Cl)CC1(C)C)C(=O)NCC(C)(C)C.CC[C@H](C[C@H](O)[C@H](CN1CC(=O)N(c2ccccc2Cl)CC1(C)C)NC(=O)OC(C)(C)C)C(=O)NCC(C)(C)C.O=C(O)/C=C/C(=O)O>>CC[C@H](C[C@H](O)[C@@H](N)CN1CC(=O)N(c2ccccc2Cl)CC1(C)C)C(=O)NCC(C)(C)C.CC[C@H](C[C@H](O)[C@@H](N)CN1CC(=O)N(c2ccccc2Cl)CC1(C)C)C(=O)NCC(C)(C)C.O=C(O)/C=C/C(=O)O,,CO,ClCCl,O=C(O)C(F)(F)F,,test
US04087522,CCCNC(=O)CP(=O)([O-])OC>>CCCNC(=O)CP(=O)(O)O,,CC(=O)O,,Br,,test
US20090137588A1,CC(C)(C)OC(=O)N1CCC(Nc2cc(Nc3ccc(Oc4ccccc4)cc3)ncn2)C1>>c1ccc(Oc2ccc(Nc3cc(NC4CCNC4)ncn3)cc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120178765A1,CC(C)CBr.COC(=O)c1cc(O)cc(C(=O)OC)c1>>COC(=O)c1cc(OCC(C)C)cc(C(=O)OC)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090023724A1,CCOC(C)=O.C[C@H](N)c1ccccc1.C[C@H](Nc1cc(Br)ncc1[N+](=O)[O-])c1ccccc1.O=[N+]([O-])c1cnc(Br)cc1Br>>C[C@@H](c1ccccc1)n1c(=O)[nH]c2cnc(-c3cccc4ncccc34)cc21,,CCOC(C)=O,,C1CCOC1,CCN(C(C)C)C(C)C,test
US20040167121A1,Clc1nc(Cl)nc(-c2ccccc2)n1.Nc1cc(C2CC2)n[nH]1>>Clc1nc(Nc2cc(C3CC3)n[nH]2)nc(-c2ccccc2)n1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US05932567,CI.Cc1ccc(C#N)cc1O>>COc1cc(C#N)ccc1C,,CN(C)C=O,,[H-].[Na+],,test
US20090192204A1,Cc1[nH]c2ccccc2c1CC(=O)O.Nc1ncc([N+](=O)[O-])s1>>Cc1[nH]c2ccccc2c1CC(=O)Nc1ncc([N+](=O)[O-])s1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20090298815A1,NCc1nccc(-c2sc(N3CCOCC3)nc2-c2cccc(NS(=O)(=O)c3cc(F)ccc3F)c2F)n1.O=C(Cl)C1CCCC1>>O=C(NCc1nccc(-c2sc(N3CCOCC3)nc2-c2cccc(NS(=O)(=O)c3cc(F)ccc3F)c2F)n1)C1CCCC1,,ClCCl,,CCN(CC)CC,,test
US20140371278A1,[N-]=[N+]=Nc1c(OCc2ccccc2)cc(C(=O)OCc2ccccc2)c(Nc2ccccc2Cl)c1F>>Nc1c(O)cc(C(=O)O)c(Nc2ccccc2Cl)c1F,[Pd],CO,,[H][H],,test
US20080300242A1,C1CCN(C2CCNCC2)CC1.COc1cc(F)c(Cl)cc1[N+](=O)[O-]>>COc1cc(N2CCC(N3CCCCC3)CC2)c(Cl)cc1[N+](=O)[O-],,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120202785A1,C1COCCN1.C[C@H](Nc1ncnc2c1ncn2C1CCCCO1)c1nc2ccc(F)c(C(=O)O)c2n1C1CC1>>C[C@H](Nc1ncnc2[nH]cnc12)c1nc2ccc(F)c(C(=O)N3CCOCC3)c2n1C1CC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080090853A1,CC(C)(C)OC(=O)C(C)(C)Br.O=C1CCNCC1>>CC(C)(C)OC(=O)C(C)(C)N1CCC(=O)CC1,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20070258887A1,COc1cccc(C2=NC(=O)CO2)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1cccc(-c2nc(OS(=O)(=O)C(F)(F)F)co2)c1,,ClCCl,,Cc1cccc(C)n1,,test
US20110046161A1,C=CCCn1c(O[C@@H]2C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C2)cc2ccccc2c1=O>>C=CCCn1c(O[C@H]2CN[C@H](C(=O)OC)C2)cc2ccccc2c1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050148627A1,CCOC(=O)/C=C/C(F)(F)F.Cc1cc(O)c(C=O)c(C)c1Cl>>CCOC(=O)C1=Cc2c(cc(C)c(Cl)c2C)OC1C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060135578A1,COc1cc(C=O)ccc1O.Cc1sc(N2CCOCC2)nc1CCl>>COc1cc(C=O)ccc1OCc1nc(N2CCOCC2)sc1C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100261701A1,CCCC[Sn](Cl)(CCCC)CCCC.COc1ncc(Br)s1>>CCCC[Sn](CCCC)(CCCC)c1cnc(OC)s1,,CCOCC,,[Li]CCCC,O=C([O-])O.[Na+],test
US20120022069A1,CC[Mg]Br.N#Cc1ccc(F)cc1>>NC1(c2ccc(F)cc2)CC1,CC(C)O[Ti](OC(C)C)(OC(C)C)OC(C)C,CCOCC,,Cl,[Na+].[OH-],test
US20060178514A1,CCN.O=C(Cl)C1CCC1>>CCNC(=O)C1CCC1,,ClCCl,,CCN(CC)CC,,test
US20050192347A1,CC(CO)(CCCCCN)c1ccccc1.O=C=NCCc1ccccc1>>CC(CO)(CCCCCNC(=O)NCCc1ccccc1)c1ccccc1,,ClCCl,,,,test
US20040186109A1,COC(=O)C(CO)NC(=O)c1ccc(F)cc1>>COC(=O)C1COC(c2ccc(F)cc2)=N1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020004518A1,CCO.O=C(O)c1ccc(C(=O)c2ccccc2)cc1>>CCOC(=O)c1ccc(C(=O)c2ccccc2)cc1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US20110105761A1,CCCCCCCBr.O=[N+]([O-])c1ccc(-n2ccnc2)cc1>>CCCCCCCn1cc[n+](-c2ccc([N+](=O)[O-])cc2)c1.[Br-],,C1CCOC1,,,,test
US05420119,COc1ccc(CS[C@H]2C[C@@H](C(=O)N3CCN(CCO)CC3)N(C(=O)OCc3ccc([N+](=O)[O-])cc3)C2)cc1.O=C(Cl)OCc1ccc([N+](=O)[O-])cc1>>COc1ccc(CS[C@H]2C[C@@H](C(=O)N3CCN(CCOC(=O)OCc4ccc([N+](=O)[O-])cc4)CC3)N(C(=O)OCc3ccc([N+](=O)[O-])cc3)C2)cc1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,,,test
US04616090,COc1cc(OC(C)=O)ccc1-c1nc2cnccc2[nH]1>>COc1cc(O)ccc1-c1nc2cnccc2[nH]1,,CO,,[Na+].[OH-],,test
US20040167131A1,CC(C)(C)OC(=O)NC1(C(=O)Nc2ccc(-c3ccccc3S(C)(=O)=O)cc2F)CC1.O=C(Nc1ccc(Cl)cn1)Oc1ccc([N+](=O)[O-])cc1>>CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2(NC(=O)Nc3ccc(Cl)cc3)CC2)c(F)c1,,CCOC(C)=O,ClCCl,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20020193596A1,CCOC(C)=O.COC(=O)[C@H](CCSC)NC(=O)c1ccc(OS(=O)(=O)c2ccc(C)cc2)cc1-c1ccccc1.Oc1cccnc1>>COC(=O)[C@H](CCSC)NC(=O)C1=C(c2ccccc2)CC(=COc2cccnc2)C=C1,,CCOC(C)=O,O,CS(C)=O,[H-].[Na+],test
US20140275028A1,BrCc1ccccc1Br.COc1ccc(N)c([N+](=O)[O-])c1>>COc1ccc(NCc2ccccc2Br)c([N+](=O)[O-])c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20030119807A1,NO.O=C(O)C[C@@H](CCCC1CCCCC1)c1nc(COc2ccc(Cl)cc2)no1.O=C(n1ccnc1)n1ccnc1>>N.O=C(C[C@@H](CCCC1CCCCC1)c1nc(COc2ccc(Cl)cc2)no1)NO,,C1CCOC1,,Cl,,test
US20150111875A1,BrCCCBr.N[C@H]1CCc2ccc(O)cc2[C@H]1Cc1ccccc1>>Oc1ccc2c(c1)[C@@H](Cc1ccccc1)[C@@H](N1CCC1)CC2,,CC#N,,CC(C)NC(C)C,,test
US20150376164A1,O=C(CC1CCN(C(=O)OCc2ccccc2)CC1)c1c[nH]c2ccc(OCc3ccccc3)cc12>>O=C(CC1CCNCC1)c1c[nH]c2ccc(OCc3ccccc3)cc12,,CO,,Cl,,test
US20090181928A1,CCOC(=O)c1ccccc1C=C[C@@H](N)CO>>O=C1N[C@@H](CO)C=Cc2ccccc21,,CC#N,Cc1ccccc1,C1CCC2=NCCCN2CC1,,test
US20110218192A1,CC(=O)N1CCC(=O)CC1.CC(=O)c1cc(-c2cccc(C#N)c2)ccc1O>>CC(=O)N1CCC2(CC1)CC(=O)c1cc(-c3cccc(C#N)c3)ccc1O2,,CO,,C1CCNC1,,test
US20160002188A1,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)CC12CC2.Cl>>Cl.O=C(OCc1ccccc1)N1CCNC2(CC2)C1,,C1CCOC1,ClCCl,,,test
US04992438,CO.Cc1cc(Cl)nc(Nc2ccc(Cl)cc2)n1>>COc1cc(C)nc(Nc2ccc(Cl)cc2)n1,,CN(C)C=O,,O,C[O-].[Na+],test
US20060211656A1,CCCCCOc1ccc2cc(CC[C@](C)(CO)NC(=O)OC(C)(C)C)ccc2c1>>CCCCCOc1ccc2cc(CC[C@@](C)(N)CO)ccc2c1,,Cl,,,,test
US05106871,COCOc1ccc(C=CC(=O)c2c(OCOC)cc(OCOC)c(CC=C(C)C)c2O)cc1CC=C(C)C>>COCOc1ccc(CCC(=O)c2c(OCOC)cc(OCOC)c(CCC(C)C)c2O)cc1CCC(C)C,[Pd],CCOC(C)=O,,[H][H],,test
US20110092497A1,CN(C)Cc1cn(-c2ccc(Nc3ncc(Br)n4ccnc34)cc2)nn1.NC(=O)c1ccc(B(O)O)cc1>>CN(C)Cc1cn(-c2ccc(Nc3ncc(-c4ccc(C(N)=O)cc4)n4ccnc34)cc2)nn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CN(C)C=O,,,test
US20030232848A1,CC(=O)OCCOc1nn(Cc2ccccc2)c(N(S(=O)(=O)c2ccc(C(C)(C)C)cc2)S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1-c1ccc2c(c1)OCO2>>CC(C)(C)c1ccc(S(=O)(=O)Nc2c(-c3ccc4c(c3)OCO4)c(OCCO)nn2Cc2ccccc2)cc1,,CCO,O,Cl,[Na],test
US04028084,COC=CC(C)=O.N#CCC(=O)NCc1ccc(Cl)c(Cl)c1>>Cc1ccc(C#N)c(=O)n1Cc1ccc(Cl)c(Cl)c1,,COCCO,,C1CN2CCN1CC2,,test
US20100233116A1,CCOC(=O)c1sc(NC(=O)NN)cc1C.COC(OC)OC>>CCOC(=O)c1sc(-n2cn[nH]c2=O)cc1C,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20090048301A1,CCOC(=O)c1cccnc1Cl.NCc1ccc(F)cc1>>CCOC(=O)c1cccnc1NCc1ccc(F)cc1,,CCOC(C)=O,CS(C)=O,CCN(CC)CC,,test
US20160106754A1,COc1ccc(N)c(SSc2cc(OC)ccc2N)c1.O=C1CC(=O)NC(c2ccccn2)C1>>COc1ccc2c(c1)SC1=C(CC(c3ccccn3)NC1=O)N2,CCN(CC)CC,CCO,,,,test
US20150336920A1,CC(C)c1ccc2c(c1)OC1(O)c3ccccc3C(=O)C21N.CN1CCN(C(=O)C(=O)O)CC1>>CC(C)c1ccc2c(c1)OC1(O)c3ccccc3C(=O)C21NC(=O)C(=O)N1CCN(C)CC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04617307,N#Cc1ccc(Cn2cncc2CCCO)cc1.O=S(Cl)Cl>>N#Cc1ccc(Cn2cncc2CCCCl)cc1,,ClCCl,,,,test
US20080188528A1,COC(=O)c1ccc[nH]c1=O.Cc1cccc(C(Br)c2cccc(C)c2)c1>>COC(=O)c1cccn(C(c2cccc(C)c2)c2cccc(C)c2)c1=O,,CN(C)C=O,,Cl,[H-].[Na+],test
US20120283297A1,CC(C)Oc1ncc(C(=O)O)cc1Cl.COc1cc2[nH]ncc2cc1C(=N)NO>>COc1cc2[nH]ncc2cc1-c1noc(-c2cnc(OC(C)C)c(Cl)c2)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050176775A1,Cc1cc(O)cc(=O)n1Cc1ccc(S(N)(=O)=O)cc1.OCc1ccc(F)cc1F>>Cc1cc(OCc2ccc(F)cc2F)cc(=O)n1Cc1ccc(S(N)(=O)=O)cc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20040110945A1,CCOC(=O)Cc1ccc2nc(Nc3ccccc3Br)oc2c1>>O=C(O)Cc1ccc2nc(Nc3ccccc3Br)oc2c1,,C1CCOC1,CO,[Na+].[OH-],,test
US05135953,Nc1cc(Cl)c(Oc2ccc(Cl)c3ccccc23)c(Cl)c1.O=C1CCC(=O)N1Cl>>Nc1cc(Cl)c(Oc2ccc(Cl)c3ccccc23)c(Cl)c1Cl,,c1ccccc1,,,,test
US20080039517A1,CC(C)(C)OC(=O)C[C@@H](CO)Nc1ccc(C#N)c(Cl)c1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC[C@H](CC(=O)OC(C)(C)C)Nc2ccc(C#N)c(Cl)c2)cc1,,c1ccncc1,,,,test
US05866560,CC(=O)OCCCCC[C@@H]1Cc2cc(OCc3ccccc3)ccc2[C@H]2CC[C@@]3(C)C(=CC[C@@H]3O)[C@H]12>>C[C@]12CC[C@@H]3c4ccc(OCc5ccccc5)cc4C[C@@H](CCCCCO)[C@H]3C1=CC[C@@H]2O,,ClCCl,,[K+].[OH-],,test
US20110166133A1,N#Cc1cccc(Nc2nc(Cl)ccc2[N+](=O)[O-])c1>>N#Cc1cccc(Nc2nc(Cl)ccc2N)c1,[Ni],CO,ClCCl,,,test
US04268675,COC(CN(C)C(=O)Nc1nnc(C(C)Oc2ccc(Cl)c(Cl)c2)s1)OC>>CC(Oc1ccc(Cl)c(Cl)c1)c1nnc(N2C(=O)N(C)CC2O)s1,,Cl,O,,,test
US20050209260A1,C#CCCl.CC(C)c1cc(O)c(I)cc1Oc1cnc(N)nc1N>>C#CCOc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1I,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090181966A1,COC(=O)C[C@H](O)COc1ccc(C(=O)N2c3ccccc3[C@H](N(C(C)=O)c3ccc(Cl)cc3)C[C@@H]2C)cc1>>CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(OC[C@@H](O)CC(=O)O)cc2)c2ccccc21,,C1CCOC1,CO,[Li+].[OH-],,test
US20120122838A1,CS(=O)(=O)N1CCC(O)CC1.C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)c1cc2cccc(Cl)c2c(Cl)n1>>C[C@H](N)c1cc2cccc(Cl)c2c(OC2CCN(S(C)(=O)=O)CC2)n1,,C1CCOC1,,O,[H-].[Na+],test
US20040132727A1,COc1cc2nccc(Oc3ccc(N)cc3C)c2cc1OC.O=C(N=C=S)c1ccc(Cl)cc1>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4ccc(Cl)cc4)cc3C)c2cc1OC,,CCO,,Cc1ccccc1,,test
US04940710,CCn1cc(C(=O)O)c(=O)c2cc(F)c(F)c(F)c21.FCC1CNCCN1>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(CF)C3)c(F)c21,,c1ccncc1,,,,test
US04374138,O=C(O)c1c[nH]c2c([N+](=O)[O-])cccc2c1=O>>Nc1cccc2c(=O)c(C(=O)O)c[nH]c12,[Ni],CN(C)C=O,,[H][H],,test
US20140112945A1,COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4ccccc4)NC(=O)OC(C)(C)C)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC.Cl>>COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)Cc4ccccc4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC.Cl,,C1COCCO1,,ClCCl,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Nc1cc[nH]n1>>COc1ccc2nc(Nc3cc[nH]n3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US20080207725A1,CCOC(=O)c1cnn(-c2ccc(F)cc2F)c1N>>Nc1c(C(=O)O)cnn1-c1ccc(F)cc1F,,CCO,,Cl,[Na+].[OH-],test
US20050096333A1,COC(=O)c1cnccc1NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)Nc1ccncc1C(=O)O,,C1COCCO1,,Cl,[Na+].[OH-],test
US20050197350A1,CN(C)c1ccnc(Cl)n1.N[C@H]1CC[C@@H](CNC(=O)OCc2ccccc2)CC1>>CN(C)c1ccnc(N[C@@H]2CC[C@H](CNC(=O)OCc3ccccc3)CC2)n1,,CC(C)O,,O=C([O-])O.[Na+],,test
US05726184,NCc1ccccc1.O=C1CCCc2ccc(OCc3ccncc3)cc21>>c1ccc(CNC2CCCc3ccc(OCc4ccncc4)cc32)cc1,,c1ccccc1,,,,test
US05554607,CCNCC(=O)O.Cc1cccc(N=C=S)c1C>>CCN1CC(=O)N(c2cccc(C)c2C)C1=S,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20080207897A1,CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(C#Cc3nccs3)c2CC1>>CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(CCc3nccs3)c2CC1,[Pd],CCO,,CC(=O)O,,test
US20120010228A1,COC(=O)c1ccc(F)cc1.O=C(OCc1ccccc1)N1CCC2(CC1)C(=O)NCN2c1ccccc1>>COC(=O)c1ccc(N2CN(c3ccccc3)C3(CCN(C(=O)OCc4ccccc4)CC3)C2=O)cc1,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US04293690,CCC(=O)OC(=O)CC.NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1N.c1ccncc1>>CCC(=O)OC[C@H]1O[C@@H](n2cnc(C(N)=O)c2N)[C@H](OC(=O)CC)[C@@H]1OC(=O)CC,,c1ccncc1,,,,test
US20060004046A1,CC(=O)O.N#Cc1cnc2ccc(C=O)cc2c1-c1ccccc1.O=C1CSC(=S)N1>>N#Cc1cnc2ccc(C=C3SC(=O)NC3=O)cc2c1-c1ccccc1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20080242699A1,COC(CNCc1ccc(F)cc1)OC.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(CN(Cc1ccc(F)cc1)S(=O)(=O)c1ccc(C)cc1)OC,,ClCCl,,c1ccncc1,,test
US20150284343A1,Br.OCc1nn(-c2ccc(C(F)(F)F)cc2)nc1Oc1cccc(OC(F)(F)F)c1>>FC(F)(F)Oc1cccc(Oc2nn(-c3ccc(C(F)(F)F)cc3)nc2CBr)c1,,CC(=O)O,O,[Na+].[OH-],,test
US20130210858A1,CN1CCCC1=O.ClC1CCOCC1.O.O=C(O)c1ccc2[nH]ncc2c1>>O=C(OC1CCOCC1)c1ccc2c(cnn2C2CCOCC2)c1,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130338134A1,COc1cc(OC)c(F)c(NCc2cnc3[nH]ccc3c2NC2CC2)c1F.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc(OC)c(F)c(N2Cc3cnc4[nH]ccc4c3N(C3CC3)C2=O)c1F,,C1CCOC1,,CCN(CC)CC,[Na+].[OH-],test
US20120157430A1,CC(=O)c1cc(F)c(C)c(Br)c1O.CI>>COc1c(C(C)=O)cc(F)c(C)c1Br,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20020045628A1,Fc1cc2c(c(N3CCN(Cc4ccccc4)CC3)c1)OCC2>>Fc1cc2c(c(N3CCNCC3)c1)OCC2,[Pd],CCO,,O=C[O-].[NH4+],,test
US20100087429A1,NC1=N[C@]2(CO1)c1cc(C3=CCOCC3)ccc1Oc1cc(F)c(O)cc12.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>NC1=N[C@]2(CO1)c1cc(C3=CCOCC3)ccc1Oc1cc(F)c(OS(=O)(=O)C(F)(F)F)cc12,,ClCCl,,,,test
US20160039865A1,C1CCNC1.C[C@]12CCC(=O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](c3ccc(=O)oc3)CC[C@]12O>>C[C@]12CCC(N3CCCC3)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](c3ccc(=O)oc3)CC[C@]12O,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20050250782A1,CCOC(=O)c1cn(C)c(=O)c(C)c1Cl.O=C1CCC(=O)N1Br>>CCOC(=O)c1c(Cl)c(C)c(=O)n(C)c1Br,,CCOC(C)=O,CN(C)C=O,,,test
US20160016966A1,CC(C)(C)OC(=O)Nc1cnccc1B(O)O.C[C@@H]1CN(S(C)(=O)=O)CCN1Cc1cc2c(=O)n(C)cc(Br)c2o1>>C[C@@H]1CN(S(C)(=O)=O)CCN1Cc1cc2c(=O)n(C)cc(-c3ccncc3NC(=O)OC(C)(C)C)c2o1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US04576933,CCCCCCCCCCCCCCCCCCOCC(O)COC(c1ccccc1)(c1ccccc1)c1ccccc1.O=C(Cl)Oc1ccccc1.c1ccncc1>>CCCCCCCCCCCCCCCCCCOCC(COC(c1ccccc1)(c1ccccc1)c1ccccc1)OC(=O)N(C)C,,ClCCl,O,ClC(Cl)Cl,,test
US20160185764A1,C[C@H]1[C@H](/C=C/c2ccc(Br)cn2)[C@@H]2[C@@H](C)OC(=O)[C@]2(N)CC1(F)F.ClCC1CO1>>C[C@H]1[C@H](/C=C/c2ccc(Br)cn2)[C@@H]2[C@@H](C)OC(=O)[C@]2(N2CC(O)C2)CC1(F)F,,CCCCO,,,,test
US20100004269A1,C=COCCONC(=O)c1ccc2cncn2c1Nc1ccc(I)cc1F>>O=C(NOCCO)c1ccc2cncn2c1Nc1ccc(I)cc1F,,CO,,Cl,,test
US20050234109A1,O=S(=O)(c1ccc(Cl)cc1)C(CCCCCO)c1cc(F)ccc1F>>O=S(=O)(c1ccc(Cl)cc1)C1(c2cc(F)ccc2F)CCCCC1,,Cc1ccccc1,,CCCCP(=CC#N)(CCCC)CCCC,,test
US20130303505A1,COS(=O)(=O)c1ccc(C)cc1.COc1cc(C(C)(C)c2cnc(SCc3c(F)cc(C#CCN(C)C)cc3F)n2-c2ccc(F)cc2)ccc1Cl>>COc1cc(C(C)(C)c2cnc(SCc3c(F)cc(C#CC[N+](C)(C)C)cc3F)n2-c2ccc(F)cc2)ccc1Cl.Cc1ccc(S(=O)(=O)[O-])cc1,,CCOCC,,,,test
US20090137561A1,CC/C=C/[C@@H](CC(=O)OC)c1cccc(O)c1>>CCCC[C@H](CC(=O)OC)c1cccc(O)c1,[Pd],CCOC(C)=O,,,,test
US20050107388A1,CCOC(=O)Cl.NCCc1cc2ccccc2cn1>>CCOC(=O)NCCc1cc2ccccc2cn1,,ClCCl,,CCN(CC)CC,,test
US04948887,COC(=O)c1ccc(S(C)(=O)=O)c(CC#N)c1Cl>>CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1CC#N,,CO,,Cl,[Na+].[OH-],test
US20070276000A1,CCOC(=O)/C=C/c1ccc(Oc2c(-c3ccc(OC)cc3)c(C)cc3ccc(OC)cc23)cc1>>COc1ccc(-c2c(C)cc3ccc(OC)cc3c2Oc2ccc(/C=C/C(=O)O)cc2)cc1,,CO,ClC(Cl)Cl,,,test
US20150152112A1,C#CC(=O)OCC.O=c1cc(OCc2ccccc2)cc[nH]1>>C=C(C(=O)OCC)n1ccc(OCc2ccccc2)cc1=O,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20120094993A1,C[C@H](O)C(F)(F)F.Fc1ncc(Cl)cc1-c1ccc(Cl)cc1>>C[C@H](Oc1ncc(Cl)cc1-c1ccc(Cl)cc1)C(F)(F)F,,CN(C)C=O,,,,test
US20050020631A1,COC(=O)c1oc2ccc(Cl)cc2c1O.COCCOCCl>>COCCOCOc1c(C(=O)OC)oc2ccc(Cl)cc12,,C1CCOC1,,[H-].[Na+],,test
US20080039440A1,COc1ccc2c(c1)CCCCN2.O=C=Nc1cccc(C(F)(F)F)c1>>COc1ccc2c(c1)CCCCN2C(=O)Nc1cccc(C(F)(F)F)c1,,CCOCC,,CCCCCC,,test
US05273986,CCOC(=O)c1ccccc1CCC(=O)O.Nc1cccc(/C=C/c2nc(C3CCC3)cs2)c1>>CCOC(=O)c1ccccc1CCC(=O)Nc1cccc(/C=C/c2nc(C3CCC3)cs2)c1,CN(C)c1ccncc1,ClCCl,,,,test
US20090318668A1,CCOC(=O)c1cc2cc(OCC3CCN(C)CC3)ccc2[nH]1.Cl>>CN1CCC(COc2ccc3[nH]c(C(=O)O)cc3c2)CC1.Cl,,CO,O,[Na+].[OH-],,test
US20090275523A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(F)(F)C[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CC(F)(F)C[C@H](NC(=O)OC(C)(C)C)C(=O)O,[Pd],CO,,[Na+].[OH-],,test
US20160159815A1,COC(=O)c1c[nH]c(=O)c(Cl)c1.O=S(=O)(OCCOC(F)(F)F)C(F)(F)F>>COC(=O)c1cnc(OCCOC(F)(F)F)c(Cl)c1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20110275797A1,CC(C)(C)OC(=O)c1ccc(Br)cc1[N+](=O)[O-].CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(C)(C)OC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1[N+](=O)[O-],,C1COCCO1,,CC(=O)[O-].[K+],,test
US20100130487A1,CCOC(=O)CN1C(=O)C2(COc3cc4c(cc32)CCO4)c2ccccc21>>O=C(O)CN1C(=O)C2(COc3cc4c(cc32)CCO4)c2ccccc21,,CCOC(C)=O,O,Cl,[Li+].[OH-],test
US06666989B1,CCCCCC[C@H](C)O.COC(=O)Oc1ccc(C(=O)O)cc1>>CCCCCC[C@@H](C)OC(=O)c1ccc(OC(=O)OC)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060258721A1,CN1CC=C(c2c[nH]c3ccc([N+](=O)[O-])cc23)C(F)C1>>CN1CC=C(c2c[nH]c3ccc(N)cc23)C(F)C1,[Ni],CO,,NN,O,test
US20080119442A1,CC(C)(C)OC(=O)N(CC=CCl)c1ccc2ccc(S(C)(=O)=O)cc2c1Br>>CC(C)(C)OC(=O)N1CC(CCl)c2c1ccc1ccc(S(C)(=O)=O)cc21,,c1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,CCCC[SnH](CCCC)CCCC,test
US20110112103A1,CC(=O)ON=C(N)Cn1ccc(-c2ccc(C(C)(C)C)cc2)cc1=O>>CC(=O)O.CC(C)(C)c1ccc(-c2ccn(CC(=N)N)c(=O)c2)cc1,[Pd],CCO,ClCCl,,,test
US05304532,Fc1ccc(C(F)(F)F)cc1.O=C=O>>O=C(O)c1cc(C(F)(F)F)ccc1F,,C1CCOC1,O,[Li]CCCC,,test
US20140163219A1,CC(C)c1ncc(C=O)s1.COc1ccc2oc(C(C)=O)c(N)c2c1Br>>COc1ccc2oc(C(=O)/C=C/c3cnc(C(C)C)s3)c(N)c2c1Br,,C1CCOC1,,O,[Na+].[OH-],test
US20020062031A1,CC(=O)c1cc2c(c(C(N)=O)c1)OCCCS2>>CC(O)c1cc2c(c(C(N)=O)c1)OCCCS2,,CCO,,Cl,[BH4-].[Na+],test
US05049669,CCN(CC)CC(C)N1c2ccccc2Sc2ccc(C#N)cc21.S>>CCN(CC)CC(C)N1c2ccccc2Sc2ccc(C(N)=S)cc21,,c1ccncc1,,CCN(CC)CC,,test
US20090137595A1,CC(C)(C)OC(=O)Nc1cn2nc(I)ccc2n1>>Nc1cn2nc(I)ccc2n1,,CCOC(C)=O,,CCOCC,Cl,test
US20120142679A1,CC(C)(C)OC(=O)n1cc(CN2c3nc(N4CCOCC4)cc(=O)n3C[C@@]2(C)C(F)(F)F)c2ccccc21>>C[C@@]1(C(F)(F)F)Cn2c(nc(N3CCOCC3)cc2=O)N1Cc1c[nH]c2ccccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160159752A1,C[C@@H](O)CN(C[C@H](CCc1c(F)cccc1NC(=O)[C@@H](N=[N+]=[N-])C(c1cccc(F)c1)c1cccc(F)c1)NS(=O)(=O)c1ccccc1)C(=O)OC(C)(C)C>>C[C@H]1CN(C(=O)OC(C)(C)C)C[C@H](CCc2c(F)cccc2NC(=O)[C@@H](N=[N+]=[N-])C(c2cccc(F)c2)c2cccc(F)c2)N1S(=O)(=O)c1ccccc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100029636A1,CC(C)COC(=O)Nc1ccc(-c2cnc3c(-c4ccc(N5CCN(C(=O)OCc6ccccc6)CC5)cc4)cnn3c2N)cc1>>CC(C)COC(=O)Nc1ccc(-c2cnc3c(-c4ccc(N5CCNCC5)cc4)cnn3c2N)cc1,[Pd],C1CCOC1,CO,,,test
US20090036450A1,Cc1ccc(C(=O)O)s1.N>>Cc1ccc(C(N)=O)s1,,COCCOC,O,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20140005213A1,BrB(Br)Br.COc1ccc2cc(F)c(C)nc2c1>>Br.Cc1nc2cc(O)ccc2cc1F,,ClCCl,,CO,,test
US20090203657A1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(Cl)c(-c3cccc(C=O)c3)c2)n1.CN1CCNCC1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(Cl)c(-c3cccc(CN4CCN(C)CC4)c3)c2)n1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140162983A1,C=CC(=O)Cl.Nc1ncnc(NC[C@@H]2CCNC[C@H]2O)c1-c1ccc(Oc2ccccc2)cc1>>C=CC(=O)N1CC[C@@H](CNc2ncnc(N)c2-c2ccc(Oc3ccccc3)cc2)[C@H](O)C1,,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US20140235628A1,CC(C)(C)OC(=O)N1CCC(NCc2ccc3c(c2)COC3=O)CC1.Cl>>O=C1OCc2cc(CNC3CC[NH2+]CC3)ccc21.[Cl-],CO,C1COCCO1,,,,test
US20150152112A1,COC(=O)Nc1ccc(-c2cnc(Cn3ccc(-c4cc(Cl)ccc4NC(=O)OC(C)(C)C)cc3=O)[nH]2)cc1>>COC(=O)Nc1ccc(-c2cnc(Cn3ccc(-c4cc(Cl)ccc4N)cc3=O)[nH]2)cc1,,C1COCCO1,,Cl,O=C([O-])O.[Na+],test
US05419966,NCCCCCCO.O=C(O)c1ccc2c(c1)C(=O)OC2=O>>O=C(O)c1ccc2c(c1)C(=O)N(CCCCCCO)C2=O,,O,,,,test
US20120010188A1,COc1cccc(C(=O)CBr)c1.Cc1ccc(N)nc1>>COc1cccc(-c2cn3cc(C)ccc3n2)c1,,CCO,,[Na+].[OH-],,test
US20020086922A1,CCCCCCCCO.CO.COC(=O)C(C)Oc1ccc(-c2nc(-c3ccc(OC(C)C(=O)OC)cc3O)nc(-c3ccc(OC(C)C(=O)OC)cc3O)n2)c(O)c1.Cc1ccc(S(=O)(=O)O)cc1.Cc1ccccc1C>>CCCCCCCCOC(=O)C(C)Oc1ccc(-c2nc(-c3ccc(OC(C)C(=O)OCCCCCCCC)cc3O)nc(-c3ccc(OC(C)C(=O)OCCCCCCCC)cc3O)n2)c(O)c1,,Cc1ccccc1C,,O,,test
US03991200,CCOC(CN)OCC.Cn1c([N+](=O)[O-])cnc1C1=CNN(NCCO)S1>>CCOC(CNN1NC=C(c2ncc([N+](=O)[O-])n2C)S1)OCC,,O,,C1COCCO1,,test
US20160145204A1,C=CCCCCC.CCC=Cc1cccc(C)c1>>CCCCCC=CCCc1ccccc1C,,ClCCl,,,,test
US20100041891A1,CC(=O)c1cccc(Br)c1F.NN>>Cc1n[nH]c2c(Br)cccc12,,CCCCCC,,CCOCC,O,test
US20100069384A1,CC(C)(C)OC(=O)NCCN.CCOc1ccc2c(c1)C(C)(c1cc(C(=O)O)ccc1Cl)C(=O)N2S(=O)(=O)c1ccc(C(=O)NC(C)(C)C)cc1OC>>CCOc1ccc2c(c1)C(C)(c1cc(C(=O)NCCN)ccc1Cl)C(=O)N2S(=O)(=O)c1ccc(C(=O)NC(C)(C)C)cc1OC,,ClCCl,,CCN(CC)CC,O,test
US20050085465A1,CC(=O)N1CCN(CCO)CC1.COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1O>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCN1CCN(C(C)=O)CC1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080027080A1,CC(C)N(C)[C@@H]1CC[C@H](N2CC[C@H](NC(=O)OCc3ccccc3)C2=O)[C@H](NC=O)C1>>CC(C)N(C)[C@@H]1CC[C@H](N2CC[C@H](N)C2=O)[C@H](NC=O)C1,[Pd],CO,,,,test
US20030170858A1,C#CCNC(=O)OC(C)(C)C.CON(C)C(=O)c1oc(-c2ccccc2)nc1-c1ccccc1>>CC(C)(C)OC(=O)NCC#CC(=O)c1oc(-c2ccccc2)nc1-c1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US05565488,CC(=O)Nc1ccc2c(C)c(C(=O)c3ccc(C)cc3)oc2c1.Cl>>Cc1c(C(=O)c2ccc(Cl)cc2)oc2cc(N)ccc12,,CO,,CCOC(C)=O,,test
US20160185785A1,CCOC(=O)c1cnc(Br)o1.OB(O)C1CC1>>CCOC(=O)c1cnc(C2CC2)o1,,O,,Cc1ccccc1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20070032530A1,ClCc1cncc(-c2ccc(Cl)cc2)c1.Oc1ccc(CCCCn2ccnn2)cc1>>Clc1ccc(-c2cncc(COc3ccc(CCCCn4ccnn4)cc3)c2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20090270350A1,COc1ccc(Cn2c(C)cc(OCc3ccccc3C#N)c(I)c2=O)c(OC)c1.C[Sn](C)(C)C>>COc1ccc(Cn2c(C)cc(OCc3ccccc3C#N)c(C)c2=O)c(OC)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,O,[Cl-].[Li+],,test
US20110098276A1,O=C1c2ccccc2C(=O)N1CCOc1ccc(F)cc1>>NCCOc1ccc(F)cc1,,CO,,NN,,test
US20100075973A1,CC(C)(C)OC(=O)N1CCC(N2CC(N)C2)CC1.CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3cc(F)c(C(=O)O)cc3OC)nc2N1C1CCCC1>>CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3ccc(C(=O)NC4CN(C5CCNCC5)C4)cc3OC)nc2N1C(C)C,,O,,,,test
US20060058320A1,NCC1CC1.Nc1nc(/C=C/CO)cc2nc(-c3ccco3)nn12>>Nc1nc(/C=C/CNCC2CC2)cc2nc(-c3ccco3)nn12,,CO,,[BH4-].[Na+],,test
US06191124B1,COC(OC)N(C)C.Cc1csc(N)n1>>Cc1csc(N=CN(C)C)n1,,Cc1ccccc1,,,,test
US20100278733A1,CI.Nc1ccc(C=CC(=O)c2ccc(I)s2)cc1>>CNc1ccc(C=CC(=O)c2ccc(I)s2)cc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20020016337A1,CCC(=O)N(CC1CCCN(C(=O)OC(C)(C)C)C1)c1ccccc1.O=Cc1ccccc1>>CCC(=O)N(CC1CCCN(Cc2ccccc2)C1)c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20110021534A1,CCOC(=O)C(Cc1ccc(O)c(Cc2ccccc2)c1)OCC>>CCOC(Cc1ccc(O)c(Cc2ccccc2)c1)C(=O)O,,CO,O,Cl,[K+].[OH-],test
US20140225069A1,CCc1cccc(CC)c1Nc1ccc(-c2ccccc2)cc1[N+](=O)[O-]>>CCc1cccc(CC)c1Nc1ccc(-c2ccccc2)cc1N,,CCOC(C)=O,,,,test
US20140206680A1,CC(C)OB(OC(C)C)OC(C)C.N#Cc1ccc2sccc2c1>>N#Cc1ccc2sc(B(O)O)cc2c1,,C1CCOC1,,[Li]CCCC,,test
US20090143385A1,CC#CC(=O)OCC.O/N=C(\Cl)c1cccc(F)c1>>CCOC(=O)c1c(-c2cccc(F)c2)noc1C,,CCOCC,,CCN(CC)CC,,test
US20090270505A1,C1=COCCC1.OCCCCCCCCCBr>>BrCCCCCCCCCOC1CCCCO1,,ClCCl,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20090325993A1,CC(C)(C)OC(=O)N1CCC2(CC1)N=C(c1ccc(Cl)cc1)C(=O)N2.O=C(CCl)Nc1ccc(F)c(F)c1>>CC(C)(C)OC(=O)N1CCC2(CC1)N=C(c1ccc(Cl)cc1)C(=O)N2CC(=O)Nc1ccc(F)c(F)c1,,CN(C)C=O,,[H-].[Na+],,test
US20100204196A1,COc1cc(N2CCOC[C@@H]2C)ccc1[N+](=O)[O-]>>COc1cc(N2CCOC[C@@H]2C)ccc1N,,CO,,NN,O,test
US07214824B2,CC(C)(C)OC(=O)COc1ccc2c(c1)CCCC2(C)C>>CC1(C)CCCc2cc(OCC(=O)O)ccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140315949A1,COC(=O)c1ccc(C(C)CCO)cc1>>CC(CCO)c1ccc(C(=O)O)cc1,,CO,O,Cl,[Li+].[OH-],test
US20120184512A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCNC(=O)Nc1nc2cc(-c3cnc(C(C)(C)O)nc3)c(F)c([C@H]3CCCO3)c2[nH]1>>CCN(C(=O)Nc1nc2cc(-c3cnc(C(C)(C)O)nc3)c(F)c([C@H]3CCCO3)c2[nH]1)C(=O)OC(C)(C)C,,CN(C)C=O,CO,N,,test
US20120309739A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4nc(S(C)(=O)=O)nc(C(F)(F)F)c4c3-c3ccccc3)cc2)CCC1.NCCO>>CC(C)(C)OC(=O)NC1(c2ccc(-c3oc4nc(NCCO)nc(C(F)(F)F)c4c3-c3ccccc3)cc2)CCC1,,C1CCOC1,,,,test
US20090274713A1,CC(O)=S.COC(=O)C(CCBr)S(=O)(=O)O>>COC(=O)C(CCSC(C)=O)S(=O)(=O)O,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US03932431,CC(C#N)(c1ccccc1)c1ccccn1.S>>CC(C(N)=S)(c1ccccc1)c1ccccn1,,CN(C)C=O,,CCN(CC)CC,,test
US20100069367A1,CS(=O)(=O)c1cccc(B(O)O)c1.FC(F)(F)c1cc(-c2cn(-c3ccc(Br)cc3Cl)c(-c3ccccc3Cl)n2)no1>>CS(=O)(=O)c1cccc(-c2ccc(-n3cc(-c4cc(C(F)(F)F)on4)nc3-c3ccccc3Cl)c(Cl)c2)c1,,CCOC(C)=O,O,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20100010090A1,CC(CN)c1ccccc1.O=C(O)C[C@H](O)C(=O)O>>C[C@@H](CN)c1ccccc1.O=C(O)CC(O)C(=O)O,,CCO,,Cl,[Na+].[OH-],test
US20090264445A1,C=Cc1cccc(OC2=CC(=O)N([C@@H](CC(C)C)C(=O)O)C2)c1F.CC1(C)OC[C@@H](Cn2ccc(N)n2)O1>>C=Cc1cccc(OC2=CC(=O)N([C@@H](CC(C)C)C(=O)Nc3ccn(C[C@@H]4COC(C)(C)O4)n3)C2)c1F,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20150376136A1,C/C=C/CC1(C)C(=O)NC(=O)N(C)C1=O.O=C(CBr)c1ccccc1>>C/C=C/CC1(C)C(=O)N(C)C(=O)N(CC(=O)c2ccccc2)C1=O,,CN(C)C=O,,[H-].[Na+],,test
US20120157430A1,Brc1ncnc2[nH]cnc12.Cc1c(Cl)cc(C(C)N)c(-c2cccc(F)c2)c1N(S(C)(=O)=O)S(C)(=O)=O>>Cc1c(Cl)cc(C(C)Nc2ncnc3[nH]cnc23)c(-c2cccc(F)c2)c1N(S(C)(=O)=O)S(C)(=O)=O,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20150353553A1,COC(=O)c1nc(N[C@H](C)C2CCC2)c2c(n1)nc(-c1ccccn1)n2Cc1ccc(C(F)(F)F)cc1>>COC(=O)c1nc(N[C@H](C)C2CCC2)c2c(n1)nc(C1CCCCN1)n2Cc1ccc(C(F)(F)F)cc1,O=[Pt]=O,CC(=O)O,,,,test
US04548932,CCOC(=O)CC(=O)OCC.Cc1ccc(S(=O)(=O)OCCCCCC2CCN(C(=O)OCc3ccccc3)CC2)cc1>>CCOC(=O)C(CCCCCC1CCN(C(=O)OCc2ccccc2)CC1)C(=O)OCC,,CCO,,[Na],,test
US06071903,COC(=O)C1CNc2ccccc2CN1S(=O)(=O)c1ccc(OC)cc1.O=C(Cl)CCl>>COC(=O)C1CN(C(=O)CCl)c2ccccc2CN1S(=O)(=O)c1ccc(OC)cc1,,ClCCl,O,CCN(CC)CC,,test
US20070043061A1,Cc1ccc(O)cc1C.ICI.N#CCCNc1nonc1-c1nc2ccccc2[nH]1>>Cc1ccc(OCn2c(-c3nonc3NCCC#N)nc3ccccc32)cc1C,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20110021537A1,CC(C)(C)OC(=O)CC[C@H](NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1)C(=O)O.O=C(OCc1ccccc1)N1CCNCC1>>O=C(O)CC[C@H](NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1)C(=O)N1CCN(C(=O)OCc2ccccc2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140027733A1,O=[N+]([O-])c1sc2ccccc2c1Nc1ccccc1>>Nc1sc2ccccc2c1Nc1ccccc1,[Fe],CC(=O)O,O,,,test
US20160016908A1,CC(=O)N1c2ccc(O)cc2[C@H](Nc2ncccn2)[C@@H](C)[C@@H]1C1CC1.OCCBr>>CC(=O)N1c2ccc(OCCO)cc2[C@H](Nc2ncccn2)[C@@H](C)[C@@H]1C1CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070232630A1,c1ccc(COc2cccc(CCNC3CCCCC3)c2)cc1>>Oc1cccc(CCNC2CCCCC2)c1,[Pd],CCO,,[H][H],,test
US06825354B2,CCOC(=O)C(Br)c1ccc(OC)cc1.Oc1ccc(S)cc1>>CCOC(=O)C(Sc1ccc(O)cc1)c1ccc(OC)cc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20020169206A1,CSc1ccc(B(O)O)cc1.O=S(=O)(c1cc(Cl)c(Cl)cc1S(=O)(=O)C(F)(F)F)C(F)(F)F>>CSc1ccc(-c2cc(Cl)c(Cl)cc2S(=O)(=O)C(F)(F)F)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20050038035A1,CC(C)(C)OC(=O)Nc1nc(CCOc2ccc(NC(=O)C3=C(c4ccc(C(F)(F)F)cc4)CCCC3)cn2)cs1>>Nc1nc(CCOc2ccc(NC(=O)C3=C(c4ccc(C(F)(F)F)cc4)CCCC3)cn2)cs1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040038962A1,N#Cc1ccc(C(=O)O)cc1.c1ccc2c(c1)CCCCN2>>N#Cc1ccc(C(=O)N2CCCCc3ccccc32)cc1,CN(C)c1ccncc1,,,CCN(CC)CC,,test
US20090036467A1,CC(=O)Oc1ccccc1C(=O)Nc1ncc(S(C)(=O)=O)s1>>CS(=O)(=O)c1cnc(NC(=O)c2ccccc2O)s1,,C1CCOC1,,Cl,,test
US20150307451A1,COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)c(C)c(C)c1O.Cc1ccc(CCl)cn1>>COC(=O)c1cc(Cc2ccc(C)nc2)c(C)c(C)c1O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US05422358,BrCCc1ccccc1.NC(=O)C(c1ccccc1)(c1ccccc1)C1CCCNC1>>NC(=O)C(c1ccccc1)(c1ccccc1)C1CCCN(CCc2ccccc2)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070112035A1,CCOC(=O)CCCOc1ccc(C(F)(F)F)cn1.COc1ccc(OCC=C(Cl)Cl)cc1C(=N)NO>>COc1ccc(OCC=C(Cl)Cl)cc1-c1noc(CCCOc2ccc(C(F)(F)F)cn2)n1,,C1CCOC1,,[H-].[Na+],,test
US04413005,CCCCNCC(=O)OCC.CNC(=O)Oc1cccc2c1OC(C)(C)C2.ClSCl>>CCCCN(CC(=O)OCC)SN(C)C(=O)Oc1cccc2c1OC(C)(C)C2,,ClCCl,,CCN(CC)CC,,test
US20100210659A1,CI.Cc1cc(C(=O)N2C[C@H](CNc3ncc(C(F)(F)F)cn3)[C@@H](c3ccc(Cl)c(Cl)c3)C2)cnn1>>Cc1cc(C(=O)N2C[C@H](CN(C)c3ncc(C(F)(F)F)cn3)[C@@H](c3ccc(Cl)c(Cl)c3)C2)cnn1,,CN(C)C=O,,[H-].[Na+],,test
US20140088101A1,CCCC[Sn](CCCC)(CCCC)c1cnn(C)c1.COC(=O)c1ncc2c(cc(Br)c(=O)n2Cc2ccccc2)c1O>>COC(=O)c1ncc2c(cc(-c3cnn(C)c3)c(=O)n2Cc2ccccc2)c1O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,CN(C)C=O,Cl,O,test
US20150166549A1,C1=COCCC1.CN(C)C=O.Cc1ccc(S(=O)(=O)O)cc1.Nc1ncnc2[nH]nc(I)c12.O>>Ic1nn(C2CCCCO2)c2ncnc(NC3CCCCO3)c12,,CN(C)C=O,,,,test
US20080009479A1,CC(C)(C)OC(=O)N1CCc2ccc(Oc3ccc(N4CCCC4=O)cn3)cc2CC1>>O=C1CCCN1c1ccc(Oc2ccc3c(c2)CCNCC3)nc1,,C1COCCO1,ClCCl,Cl,,test
US20120184562A1,CC1(C)OCC(CN)O1.COC(=O)c1cc2cnc(Cl)cc2[nH]c1=O>>COC(=O)c1cc2cnc(NCC3COC(C)(C)O3)cc2[nH]c1=O,,CS(C)=O,,CCN(CC)CC,O,test
US20150218170A1,OCc1cn(CO)c2nc(Cl)c(Br)nc12>>O=Cc1c[nH]c2nc(Cl)c(Br)nc12,,CC(C)=O,,,,test
US20100210704A1,Cc1cc(F)c(-n2nc(OCC(F)(F)C(F)(F)F)cc2C#N)cc1SCC(F)(F)F.O=C(OO)c1cccc(Cl)c1>>Cc1cc(F)c(-n2nc(OCC(F)(F)C(F)(F)F)cc2C#N)cc1S(=O)CC(F)(F)F,,ClC(Cl)Cl,,,,test
US04490370,CC(C)(C)OC(=O)OC(C)(C)C.O=C(O)CNc1ccc2ccccc2c1>>CC(C)(C)OC(=O)N(CC(=O)O)c1ccc2ccccc2c1,,[Na+],[OH-],C1CCOC1,,test
US20150283256A1,C=COC(C)=O.CC(C)(C)OC(=O)NCCCCC(=O)O>>C=COC(=O)CCCCNC(=O)OC(C)(C)C,[Pd],CCOCC,,[K+].[OH-],,test
US06008237,C=CCc1c(O)ccc2c(CC(C)(C)C)coc12>>CCCc1c(O)ccc2c(CC(C)(C)C)coc12,[Pd],COC(C)(C)C,,,,test
US07745450B2,CC(=O)Nc1c(C(N)=O)n[nH]c1C(C)C>>Cc1nc(O)c2[nH]nc(C(C)C)c2n1,,[Na+],[OH-],,,test
US20070208017A1,CC(C)(Cc1ccc2c(c1)c1cc(OCC3CC3)ccc1c1[nH]c(-c3c(Br)cccc3Br)nc21)O[Si](C)(C)C(C)(C)C>>CC(C)(O)Cc1ccc2c(c1)c1cc(OCC3CC3)ccc1c1[nH]c(-c3c(Br)cccc3Br)nc21,,O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100087433A1,Nc1cncc(Br)c1.OB(O)c1ccoc1>>Nc1cncc(-c2ccoc2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US20070244169A1,Cc1ccc([N+](=O)[O-])c(C#N)c1C>>Cc1ccc(N)c(C#N)c1C,[Pd],C1CCOC1,CCO,,,test
US20090221654A1,C1=COCCC1.CC(C)OC(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@H](F)[C@@H]1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>CC(C)OC(=O)CCC/C=C\C[C@H]1[C@@H](OC2CCCCO2)C[C@H](F)[C@@H]1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,Cc1ccc(S(=O)(=O)O)cc1,ClCCl,,,,test
US04582919,COc1c(C)c(C)c(OC)c(CC[C@](C)(O)CO)c1C.Cc1ccc(S(=O)(=O)Cl)cc1.c1ccncc1>>COc1c(C)c(C)c(OC)c(CC[C@](C)(O)COS(=O)(=O)c2ccccc2C)c1C,,ClCCl,,Cl,,test
US20110105470A1,BrCCCc1ccccc1.O=C1C(=O)c2ccccc2C2=C1SCC1(CCNCC1)O2>>O=C1C(=O)c2ccccc2C2=C1SCC1(CCN(CCCc3ccccc3)CC1)O2,,CC#N,,CCN(CC)CC,,test
US20040259912A1,COC(=O)c1cc(N)ccc1OC(c1ccccc1)c1ccccc1F.COc1ccc(N=C=O)cc1OC>>COC(=O)c1cc(NC(=O)Nc2ccc(OC)c(OC)c2)ccc1OC(c1ccccc1)c1ccccc1F,,C1CCOC1,,,,test
US20100204196A1,Cc1ccc(S(=O)(=O)n2ccc3c(Cl)nc(Cl)nc32)cc1.Nc1cc(F)cc(F)c1C(=O)O>>Cc1ccc(S(=O)(=O)n2ccc3c(Nc4cc(F)cc(F)c4C(=O)O)nc(Cl)nc32)cc1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20030100560A1,COc1cc2ccc3c4cc(OCc5ccccc5)c(OC)cc4nnc3c2cc1OC>>COc1cc2nnc3c4cc(OC)c(OC)cc4ccc3c2cc1O,[Pd],CCOC(C)=O,,,,test
US20080261977A1,COC(=O)c1cnc(Nc2cccc(C#N)c2)nc1C(F)(F)F>>N#Cc1cccc(Nc2ncc(C(=O)O)c(C(F)(F)F)n2)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20060030583A1,Oc1cccc(-c2cnc3[nH]cc(C4=CCCCC4)c3c2)c1>>Oc1cccc(-c2cnc3[nH]cc(C4CCCCC4)c3c2)c1,[Pd],CO,,,,test
US20080009486A1,C=C(N=Cc1cccc(F)c1)O[Si](C)(C)C.CCOC(=O)N1C(=O)/C(=C\c2cccc(Cl)c2)c2ccc(Cl)cc21>>CCOC(=O)N1C(=O)C2(c3ccc(Cl)cc31)C(c1cccc(Cl)c1)CC(=O)NC2c1cccc(F)c1,,Cc1ccccc1,,,,test
US20130145966A1,CO[Si](C)(C)C.CO[Si](C)(OC)OC.[K+].[OH-]>>CO[Si](C)(C)C.CO[Si](C)(OC)OC.[K+].[OH-],,CO,O,C[Si](C)(C)Cl,,test
US20090318421A1,C[C@H](CC#N)N(C(=O)[O-])C(C)(C)C.C[C@H](CCN)N(C(=O)[O-])C(C)(C)C>>C[C@H](CCN)NC(=O)OC(C)(C)C,[Ni],CCO,,N,,test
US20110166130A1,COc1cc(Cl)cc(OC)c1OC>>COc1cc(Cl)cc(OC)c1O,,ClCCl,,ClB(Cl)Cl,,test
US20090233879A1,CC(=O)OC1(C)[C@@H](COC(=O)c2ccccc2)OC(n2cc(C)c(=O)[nH]c2=O)[C@]1(C)F>>Cc1cn([C@@H]2OC(CO)[C@@](C)(O)C2(C)F)c(=O)[nH]c1=O,,N,,CO,,test
US20060100201A1,FC1CCNCC1.O=[N+]([O-])c1ccc(Cl)cc1F>>O=[N+]([O-])c1ccc(Cl)cc1N1CCC(F)CC1,,CCOC(C)=O,Cc1ccccc1,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20140322229A1,CN1CCc2[nH]c3ccccc3c2C1.O=C1CCC(=O)N1Br>>CN1CCc2c(Br)c3ccccc3n2C1,,ClC(Cl)Cl,,O,O=C([O-])O.[Na+],test
US04999369,COS(=O)(=O)OC.c1ccc2c(c1)[nH]c1c3ccccc3sc21>>Cn1c2ccccc2c2sc3ccccc3c21,,CCCCCC,ClCCl,,,test
US20100160258A1,CC(F)(F)[C@@H]1CC[C@@H](Oc2ccc3cc([C@]4(C)COC(=O)N4)ccc3c2C(F)(F)F)CC1>>CC(F)(F)[C@@H]1CC[C@@H](Oc2ccc3cc([C@@](C)(N)CO)ccc3c2C(F)(F)F)CC1,,CCO,O,[Li+].[OH-],,test
US20130053380A1,CI.COc1ccccc1S(=O)(=O)N1Cc2ccccc2C(=O)NCC1Cc1ccccc1>>COc1ccccc1S(=O)(=O)N1Cc2ccccc2C(=O)N(C)CC1Cc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US04117164,NCC1CCc2ccc([N+](=O)[O-])cc2C(O)C1>>NCC1C=Cc2cc([N+](=O)[O-])ccc2CC1,,C1COCCO1,,O=S(=O)(O)O,,test
US20020107253A1,O=CCCC1CC(c2ccccc2)=NO1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>c1ccc(C2=NOC(CCCN3CCN(C(c4ccccc4)c4ccccc4)CC3)C2)cc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20030171428A1,COC(=O)c1cc(OC)cc2cc(-c3ccc(OC)c(F)c3)oc12>>COc1cc(CO)c2oc(-c3ccc(OC)c(F)c3)cc2c1,,C1CCOC1,,[Li],,test
US20130217762A1,CC(C)(C)OC(=O)N[C@H]1CCC[C@@H]1O[Si](C)(C)C>>CC(C)(C)OC(=O)N[C@H]1CCC[C@@H]1O,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100261687A1,O=C(NCc1cccc([N+](=O)[O-])c1)NC1CCCCC1>>Nc1cccc(CNC(=O)NC2CCCCC2)c1,[Ni],CCO,,CN(C)C=O,,test
US07932274B2,CC(=O)c1cccc(Br)n1.C[C@@H]1C[C@H]1C(=O)Nc1snc(Br)c1Br>>CC(C)(O)c1cccc(Br)n1,,C1CCOC1,CCOC(C)=O,O,,test
US05817669,CO[C@@H]1CN(Cc2ccccc2)C[C@H]1N.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>CO[C@@H]1CN(Cc2ccccc2)C[C@H]1N.O=C(O)[C@H](O)[C@@H](O)C(=O)O,,CO,,,,test
US05763450,COc1ccc(CCl)cc1.O=S(=O)(Nc1ccc(Br)cc1)C(F)(F)F>>COc1ccc(CN(c2ccc(Br)cc2)S(=O)(=O)C(F)(F)F)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04628057,CCOC(=O)[C@@H]1Cc2c([nH]c3ccccc23)CN1.ClCc1ccc(Cl)cc1.S=C=S>>CCOC(=O)[C@@H]1Cc2c([nH]c3ccccc23)CN1C(=S)SCc1ccc(Cl)cc1,,CCO,,CCN(CC)CC,,test
US20130274241A1,CC(C)(C)OC(=O)n1nc(-c2cn(-c3ccc(C(=O)N4CCOCC4)cc3)nn2)c2cc(Cn3nc(Cl)ccc3=O)ccc21.OB(O)c1ccc(O)cc1>>O=C(c1ccc(-n2cc(-c3n[nH]c4ccc(Cn5nc(-c6ccc(O)cc6)ccc5=O)cc34)nn2)cc1)N1CCOCC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,O,[Cs+].[F-],,test
US04544401,COc1nc(N=C=S)nc(OC)n1.NS(=O)(=O)c1cccnc1>>COc1nc(NC(=S)NS(=O)(=O)c2cccnc2)nc(OC)n1,,CC(C)=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US04506368,COc1ccc(C(=O)CNC(=O)c2ccncc2)cc1>>COc1ccc(-c2cnc(-c3ccncc3)o2)cc1,,CC(=O)OC(C)=O,,O=P(O)(O)O,,test
US20070135385A1,COc1ccnc2c1cc(C)n2Cc1ccccc1>>Cc1cc2c(O)ccnc2n1Cc1ccccc1,,CN(C)C=O,,Cl,[Cl-].[NH4+],test
US20050107408A1,C[C@@H](N)CO.C[C@H](O)Cn1c(=O)c(Oc2ccc(F)cc2F)cc2cnc(S(C)(=O)=O)nc21>>C[C@H](O)Cn1c(=O)c(Oc2ccc(F)cc2F)cc2cnc(N[C@H](C)CO)nc21,,C1CCOC1,,,,test
US20150045340A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N=C(N)c1csc(OCCO)n1>>CC(C)(C)OC(=O)NC(=N)c1csc(OCCO)n1,,C1COCCO1,O,Cl,O=C([O-])O.[Na+],test
US20050288318A1,COC=O.NNc1ccc(Br)cc1>>O=CNNc1ccc(Br)cc1,,O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20060014826A1,CCOC(=O)C1C(=O)CC(=O)C2CCCCC21.O=C=Nc1cccc(C(F)(F)F)c1>>CCOC(=O)C1C(=O)C(C(=O)Nc2cccc(C(F)(F)F)c2)C(=O)C2CCCCC21,,C1CCOC1,,[H-].[Na+],,test
US04082793,CCOC(C)=O.ClP(Cl)c1ccccc1.F[B-](F)(F)F.N#[N+]c1ccc(S(=O)(=O)c2ccccc2)cc1.Nc1ccc(S(=O)(=O)c2ccccc2)cc1.O>>F[B-](F)(F)F.N#[N+]c1ccc(S(=O)(=O)c2ccccc2)cc1.O=P(O)(c1ccccc1)c1ccc(S(=O)(=O)c2ccccc2)cc1,Cl[Cu],,,,,test
US04968668,CCOC(=O)C(C)Cc1cccc(C)c1>>Cc1cccc(CC(C)CO)c1,,C1CCOC1,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20130131050A1,CCOc1nc2c(Cl)nccc2c(=O)n1-c1ccc(OCC(F)(F)F)cc1.COCCO>>CCOc1nc2c(OCCOC)nccc2c(=O)n1-c1ccc(OCC(F)(F)F)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US04777267,COc1ccc(S)cc1.Cc1oc(=O)oc1CCl>>COc1ccc(SCc2oc(=O)oc2C)cc1,,ClCCl,,CCN(CC)CC,,test
US20050239781A1,C=C(CC(=O)O)C(=O)O.CN(C)CCN>>CN(C)CCN1CC(C(=O)O)CC1=O,,CO,,,,test
US04014882,CCOP(=O)(Cl)OCC.CN(C)c1nc(O)cc(C(F)(F)F)n1>>CCOP(=O)(OCC)Oc1cc(C(F)(F)F)nc(N(C)C)n1,,CCOC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090042897A1,CCOC(=CC(=O)C(F)(F)F)OCC.N>>CCO/C(N)=C/C(=O)C(F)(F)F,,CC#N,,CO,,test
US20070244132A1,CCOC(=O)c1ccc(-c2cc3nc[nH]c(=O)c3[nH]2)cc1.O=P(Cl)(Cl)Cl>>CCOC(=O)c1ccc(-c2cc3ncnc(Cl)c3[nH]2)cc1.Cl,,C1COCCO1,,,,test
US20120149704A1,COCC(C)Oc1cc(OCc2ccccc2)cc(C(=O)OC)c1>>COCC(C)Oc1cc(O)cc(C(=O)OC)c1,[Pd],CO,,,,test
US20080207654A1,CCCc1nc(CC)c(-c2ccc(F)cc2)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCc1nc(CC)c(-c2ccc(F)cc2)c(=O)n1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,O,,CS(C)=O,[Cl-].[Na+],test
US20090227566A1,COCOc1cc(C(C)C)ccc1C(=O)Nc1ccccc1C(=O)Nc1ccc(Cl)cn1>>CC(C)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2ccc(Cl)cn2)c(O)c1,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20100261701A1,O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1cc(Br)c2cnccc2c1>>O=S(=O)(Oc1cc(Br)c2cnccc2c1)C(F)(F)F,,ClC(Cl)Cl,,CCN(CC)CC,,test
US05480902,N#Cc1cc(C(F)(F)F)[nH]c1-c1cccs1.[O-]Cl>>N#Cc1c(-c2cccs2)[nH]c(C(F)(F)F)c1Cl,,C1CCOC1,CCCCCC,CCOC(C)=O,,test
US20080269305A1,CCCCc1nc(Br)c(C=O)[nH]1.COC(=O)c1ccc(CBr)c(F)c1F>>CCCCc1nc(Br)c(C=O)n1Cc1ccc(C(=O)OC)c(F)c1F,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130303515A1,COC(=O)CCCBr.C[C@@H](N)c1ccc(Cl)cc1>>COC(=O)CCCN[C@H](C)c1ccc(Cl)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060120956A1,O=C1CCC(=O)N1Br.O=C1NC(=O)C(c2ccc(Oc3ccc(I)cc3)cc2)C(=O)N1>>O=C1NC(=O)C(Br)(c2ccc(Oc3ccc(I)cc3)cc2)C(=O)N1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US04820703,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C1CN=C(c2ccccc2Cl)c2cc(CCc3ccccc3)sc2N1>>S=C1CN=C(c2ccccc2Cl)c2cc(CCc3ccccc3)sc2N1,,Cc1ccccc1,,,,test
US06180637B2,COc1ccc2c(c1)c(O)nn2Cc1cccc([N+](=O)[O-])c1.O=C=Nc1ccccc1F>>COc1ccc2c(c1)c(=O)n(C(=O)Nc1ccccc1F)n2Cc1cccc([N+](=O)[O-])c1,,C1CCOC1,,,,test
US20140274688A1,O=C(O)CCc1cccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)c1>>OCCCc1cccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)c1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20130190332A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4ccc(CO)cn4c3-c3ccccc3)cc2)CCC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4ccc(CCl)cn4c3-c3ccccc3)cc2)CCC1,,ClCCl,,CCN(CC)CC,,test
US20150284362A1,Fc1ccc2c(c1)c1cc(F)ccc1n2C[C@@H]1CO1.NCCN>>NCCNC[C@H](O)Cn1c2ccc(F)cc2c2cc(F)ccc21,,CCO,,,,test
US20150038528A1,CCCCOC(=O)c1nc(C#N)c2ccc(Oc3c(C)cccc3C)cc2c1O.NCCCCC(=O)O>>Cc1cccc(C)c1Oc1ccc2c(C#N)nc(C(=O)NCCCCC(=O)O)c(O)c2c1,,COCCO,,C[O-].[Na+],,test
US05026856,CCn1cc(C(=O)O)c(=O)c2cc(F)c(F)c(F)c21.Nc1cccc2c1CNC2>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3Cc4cccc(N)c4C3)c(F)c21,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20120225062A1,CC(C)(C)[Si](C)(C)Cl.Oc1cc(F)cc(F)c1>>CC(C)(C)[Si](C)(C)Oc1cc(F)cc(F)c1,,CN(C)C=O,,c1c[nH]cn1,,test
US20150166565A1,CCOC(=O)Cc1nc(N(C)C2CC2)c2c3c(sc2n1)CCCC3.CN>>CNC(=O)Cc1nc(N(C)C2CC2)c2c3c(sc2n1)CCCC3,,CCO,,,,test
US20090156594A1,Cn1cc(-c2nnc(N)s2)cn1.O=CC(Cl)Cc1ccc2ncccc2c1>>Cn1cc(-c2nn3c(Cc4ccc5ncccc5c4)cnc3s2)cn1,,CCO,,,,test
US20030078282A1,CC(=O)c1cccc(Br)c1.CCOC(=O)C(C)P(=O)(OCC)OCC>>CCOC(=O)C(C)=C(C)c1cccc(Br)c1,,Cc1ccccc1,,CC(C)(C)[O-].[K+],,test
US20130053565A1,CC(C)(C)OC(=O)N1CC(=O)C1.CCCC#CCCC>>CCCC1=C(CCC)C(=O)CN(C(=O)OC(C)(C)C)C1,,Cc1ccccc1,,,,test
US20090209607A1,CO.COC(=O)c1sc(-c2ccnn2C)c(Br)c1O>>COC(=O)c1sc(-c2ccnn2C)c(Br)c1OC,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050014833A1,COc1ccc(C=O)cc1CNC(=O)OC(C)(C)C>>COc1ccc(CO)cc1CNC(=O)OC(C)(C)C,,C1CCOC1,CCO,O,[BH4-].[Na+],test
US20140018319A1,N#Cc1cc(N)c(Cl)c(N2CC[C@H]3NC(=O)CO[C@@H]3C2)c1>>N#Cc1cc(N)c(Cl)c(N2CC[C@H]3NCCO[C@@H]3C2)c1,,C1CCOC1,,B,CSC,test
US20150045349A1,CC(=O)OCc1cc(Cl)c(C#N)c(=O)n1-c1ccccc1Cl.NN>>Nc1n[nH]c2cc(CO)n(-c3ccccc3Cl)c(=O)c12,,CCO,,O,,test
US20040235810A1,CC#C[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@@H](c3ccc(N(C)CCO[C@H]4CC[C@]5(C)[C@H]6C[C@H](O)[C@]7(C)[C@@H]([C@H](C)CC(C)C(=O)O)CC[C@H]7[C@@H]6[C@H](OC(=O)Oc6ccc([N+](=O)[O-])cc6)C[C@@H]5C4)cc3)C[C@@]21C.CC(C)(C)OC(=O)NCCO>>CC#C[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@@H](c3ccc(N(C)CCO[C@H]4CC[C@]5(C)[C@H]6C[C@H](O)[C@]7(C)[C@@H]([C@H](C)CC(C)C(=O)O)CC[C@H]7[C@@H]6[C@H](OC(=O)OCCNC(=O)OC(C)(C)C)C[C@@H]5C4)cc3)C[C@@]21C,CN(C)c1ccncc1,CC#N,,CCN(C(C)C)C(C)C,,test
US20110319378A1,CC[C@@H](CS(=O)(=O)NC1COC1)N1C(=O)[C@@](C)(CC(=O)OC)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1>>CC[C@@H](CS(=O)(=O)NC1COC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20050215577A1,COCn1c2c(c3cc(Cl)ccc31)CCC(C(C)(COC)S(=O)(=O)c1ccccc1)C2>>COCC(C)(C1CCc2c([nH]c3ccc(Cl)cc23)C1)S(=O)(=O)c1ccccc1,Cl,C1CCOC1,CO,O=C([O-])O.[Na+],,test
US04125729,COC(=O)C(Br)c1ccc(Oc2ccc(Cl)cc2)cc1.Oc1ccc(F)cc1>>COC(=O)C(Oc1ccc(F)cc1)c1ccc(Oc2ccc(Cl)cc2)cc1,,CO,,C[O-].[Na+],,test
US20110124665A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)/C=C/[C@@H]1C[C@H](O)CCN1[C@H](C)c1ccccc1>>COC(=O)CC[C@@H]1C[C@H](O)CCN1C(=O)OC(C)(C)C,[Pd],CC(C)O,,,,test
US06803380B1,CS(=O)(=O)c1ccc(-c2nc(C(F)(F)F)nn2-c2ccc([N+](=O)[O-])cc2)cc1>>CS(=O)(=O)c1ccc(-c2nc(C(F)(F)F)nn2-c2ccc(N)cc2)cc1,[Fe],O,,CCO,[Cl-].[NH4+],test
US20090042929A1,CCN(CC)CC.NCc1cccs1.O=C(O)C1CC2C=CC1C2>>O=C(NCCc1cccs1)C1CC2C=CC1C2,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20160009744A1,Cc1sc(C(=O)c2cncnc2N[C@@H]2C[C@H](COS(N)(=O)=O)[C@@H](OC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)C2)cc1[C@@H]1OCCc2ccc(Cl)cc21>>Cc1sc(C(=O)c2cncnc2N[C@@H]2C[C@H](COS(N)(=O)=O)[C@@H](OC(=O)[C@@H](N)C(C)C)C2)cc1[C@@H]1OCCc2ccc(Cl)cc21,,C1COCCO1,,Cl,,test
US20060035920A1,CCI.Cc1c2c(=O)[nH]c3ccc(I)cc3c2nn1C1CCCCO1>>CCn1c(=O)c2c(C)n(C3CCCCO3)nc2c2cc(I)ccc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130210858A1,CCn1cc2cc(CN3C(=O)c4ccccc4C3=O)ccc2n1>>CCn1cc2cc(CN)ccc2n1,,CO,,NN,O,test
US20070281921A1,CCN1CCNCC1.Nc1cc(Cl)ncn1>>CCN1CCN(c2cc(N)ncn2)CC1,,Cc1ccccc1,,,,test
US20160009712A1,CC(C)(C)OC(=O)N1CCC[C@@H](COc2nc(Cl)c(Br)n3cncc23)C1>>Clc1nc(OC[C@@H]2CCCNC2)c2cncn2c1Br,,ClCCl,,C1COCCO1,Cl,test
US20090325981A1,CC(C)[Si](Cl)(C(C)C)C(C)C.COc1cccc(C=O)c1O>>COc1cccc(C=O)c1O[Si](C(C)C)(C(C)C)C(C)C,,CCOC(C)=O,,c1c[nH]cn1,,test
US20130217709A1,COC(=O)C1=CCCN(C)C1.Cc1ccc(Br)cc1F>>COC(=O)C1CN(C)CCC1c1ccc(C)c(F)c1,,CCOCC,,,,test
US20130303518A1,Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCCCC1)CCC2.O=C1Cc2cc(F)ccc2N1>>Cc1cn(C=C2C(=O)Nc3ccc(F)cc32)c2c1C(=O)N(CCN1CCCCC1)CCC2,,CCO,,C1CCNCC1,,test
US04622405,COc1ccc2c(c1OC)CC1CN(Cc3ccccc3)CC21.Cl>>COc1ccc2c(c1OC)CC1CNCC21.Cl,[Pd],CO,,,,test
US20100197725A1,CCOCCNCCc1ccccc1Br.COC(=O)Cl>>CCOCCN(CCc1ccccc1Br)C(=O)OC,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,[Cl-].[NH4+],test
US20120202785A1,CC[C@H](N)c1nc2ccc(F)cc2n1-c1ccccc1.Clc1ncnc2c1ncn2C1CCCCO1>>CC[C@H](Nc1ncnc2c1ncn2C1CCCCO1)c1nc2ccc(F)cc2n1-c1ccccc1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20040077646A1,Cn1c(C(=O)N[C@H]2CCCC[C@H]2C(=O)NC(C#N)CC2CCN(C(=O)OC(C)(C)C)CC2)cc2ccccc21>>Cn1c(C(=O)N[C@H]2CCCC[C@H]2C(=O)NC(C#N)CC2CCNCC2)cc2ccccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090171008A1,C#CCOC(=O)C=C.CCCCCCCCCCCCCCCCN=[N+]=[N-]>>C=CC(=O)OCc1cn(CCCCCCCCCCCCCCCC)nn1,,CN(C)C=O,,O,,test
US20030145641A1,Cc1c[nH]nc1C.O=P(O)(O)O>>Cc1c[nH+][nH]c1C.O=P([O-])(O)O,,O,,,,test
US06307056B1,N#Cc1cccc(C(=O)Cl)c1.Nc1cccc(-c2cccc3c2/C(=C/c2ccc[nH]2)C(=O)N3)c1>>N#Cc1cccc(C(=O)Nc2cccc(-c3cccc4c3/C(=C/c3ccc[nH]3)C(=O)N4)c2)c1,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20020037910A1,O=C(Cl)C1CCC1.OCc1ccccc1>>O=C(OCc1ccccc1)C1CCC1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20150225390A1,COC(=O)c1ccc(C=O)c([N+](=O)[O-])c1.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>COC(=O)c1ccc(-c2cnco2)c([N+](=O)[O-])c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20050187390A1,CC(=O)c1cc(-c2ccc(Cl)cc2)oc1C.O=C(O)c1ccc2c(c1)nc(-c1ccc3nc(-c4cc(Br)ccc4O)ccc3c1)n2C1CCCCC1>>Cc1oc(-c2ccc(Cl)cc2)cc1-c1ccc2cc(-c3nc4cc(C(=O)O)ccc4n3C3CCCCC3)ccc2n1,,CCO,,[K+].[OH-],,test
US20070197504A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2cc(I)ccc2O)CC1.FC(F)Cl>>CC(C)(C)OC(=O)N1CCN(C(=O)c2cc(I)ccc2OC(F)F)CC1,,CC(C)O,,[K+].[OH-],,test
US06982260B1,COc1ccc2cnc(Cl)nc2c1C(C)C.Nc1ccccc1>>COc1ccc2cnc(Nc3ccccc3)nc2c1C(C)C,,CC#N,,,,test
US20140323463A1,CCc1nc(C(N)=O)c(Cl)nc1Oc1cccc([N+](=O)[O-])c1.CN1CCN(c2ncc(N)cn2)CC1>>CCc1nc(C(N)=O)c(Nc2cnc(N3CCN(C)CC3)nc2)nc1Oc1cccc([N+](=O)[O-])c1,,CCOC(C)=O,CN1CCCC1=O,CCN(C(C)C)C(C)C,,test
US20080194535A1,CCOC(OCC)OCC.CO.COc1ccc(Br)c(C=O)c1>>COc1ccc(Br)c(C(OC)OC)c1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20020143034A1,CS(=O)(=O)Nc1cc([C@@H](O)CN[C@H](CO)Cc2ccc(Oc3ccnc4ccccc34)cc2)ccc1OCc1ccccc1>>CS(=O)(=O)Nc1cc([C@@H](O)CN[C@H](CO)Cc2ccc(Oc3ccnc4ccccc34)cc2)ccc1O,[Pd],CO,,,,test
US20100179150A1,C1COCCN1.CCOC(=O)c1sc(N2CCC(NC(=O)c3[nH]c(C)c(Cl)c3Cl)C(OC)C2)nc1C=O>>CCOC(=O)c1sc(N2CC[C@H](NC(=O)c3[nH]c(C)c(Cl)c3Cl)[C@H](OC)C2)nc1CN1CCOCC1,,Cl,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05730954,C.Oc1ccc(O)cc1>>C.Oc1ccc(O)cc1,,CCCO,,,,test
US04223142,CCCCNc1nc(C)c(C#N)cc1C(=O)OCC.O=[Se]=O>>CCCCNc1nc(C=O)c(C#N)cc1C(=O)OCC,,CCOCC,,,,test
US20120283264A1,O=C1N[C@H](c2cccc(C#Cc3ccccc3)c2)[C@@H](C(=O)O)O1.O=S(Cl)Cl>>O=C1N[C@H](c2cccc(C#Cc3ccccc3)c2)[C@@H](C(=O)Cl)O1,,ClCCl,,,,test
US20080058535A1,COC(=O)C1CC1(C#N)c1ccc(Cl)c(Cl)c1>>N#CC1(c2ccc(Cl)c(Cl)c2)CC1CO,,C1CCOC1,,B,CSC,test
US20120232056A1,COC(=O)c1ccc2nc(-c3ccc(N)c([N+](=O)[O-])c3)c(N3CCC[C@@H]3C)nc2c1>>COC(=O)c1ccc2nc(-c3ccc(N)c(N)c3)c(N3CCC[C@@H]3C)nc2c1,[Fe],CO,,[Cl-].[NH4+],,test
US04066768,CC(=O)CC(=O)c1ccc(C)nc1.COCCCCOc1ccc(OCC(O)CN)cc1>>COCCCCOc1ccc(OCC(O)CNC(C)=CC(=O)c2ccc(C)nc2)cc1,,O=CO,,CCO,,test
US20110263612A1,Nc1ccc(-c2cc3c(cc2Cl)OCC3)cn1.O=C(Cl)c1ccccc1F>>O=C(Nc1ccc(-c2cc3c(cc2Cl)OCC3)cn1)c1ccccc1F,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20140057299A1,Nc1ccc(N2CCN(CCCCOc3ccc4c(c3)NC(=O)CC4)CC2)c(Cl)c1Cl.O=C1CCCC(=O)O1>>O=C(O)CCCC(=O)Nc1ccc(N2CCN(CCCCOc3ccc4c(c3)NC(=O)CC4)CC2)c(Cl)c1Cl,,c1ccncc1,,,,test
US20110071126A1,C[Si](C)(C)N=C=N[Si](C)(C)C.N#Cc1cccc(-c2ccc3c(c2)C(=O)C2(CCc4ccccc4C2)C3)c1>>N#C/N=C1\c2cc(-c3cccc(C#N)c3)ccc2CC12CCc1ccccc1C2,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20100130468A1,CC[Si](CC)(CC)OC(C)(C)CCc1ccc(-c2cc(C(N)=O)c3[nH]cc(C4CCS(=O)(=O)CC4)c3c2)s1>>CC(C)(O)CCc1ccc(-c2cc(C(N)=O)c3[nH]cc(C4CCS(=O)(=O)CC4)c3c2)s1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20070037877A1,CN(C)C=O.COCCc1c(-c2ccc(OC)cc2OC)c(=O)oc2cc(OS(=O)(=O)C(F)(F)F)ccc12>>COCCc1c(-c2ccc(OC)cc2OC)c(=O)oc2cc(C#N)ccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,CCOC(C)=O,,test
US20100160258A1,C[C@@]1(c2ccc3cc(O)ccc3c2)COC(=O)N1.OC1CCC(C(F)(F)F)CC1>>C[C@@]1(c2ccc3cc(OC4CCC(C(F)(F)F)CC4)ccc3c2)COC(=O)N1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160060197A1,Br[Mg]C1CC1.CC(C)c1cccc(C(=O)C2CC2)c1O>>CC(C)c1cccc(C(O)(C2CC2)C2CC2)c1O,,C1CCOC1,,,,test
US20030018067A1,CCCCCc1c(-c2ccc3c(Br)c(OCC#N)ccc3c2)oc2ccccc12.[N-]=[N+]=[N-]>>CCCCCc1c(-c2ccc3cc(OCc4nnn[nH]4)ccc3c2)oc2ccccc12,,CN(C)C=O,,[Cl-].[NH4+],,test
US20080004327A1,Cc1cc(C(F)(F)F)co1.O=C1CCC(=O)N1Br>>FC(F)(F)c1coc(CBr)c1,CC(C)(C#N)N=NC(C)(C)C#N,ClC(Cl)(Cl)Cl,,,,test
US20160009701A1,CCOC(=O)c1ccc2c(c1)[nH]c1c(C(N)=O)cc(-c3c(C)noc3C)c(F)c12>>Cc1noc(C)c1-c1cc(C(N)=O)c2[nH]c3cc(C(=O)O)ccc3c2c1F,,C1CCOC1,CO,[Na+].[OH-],,test
US06060432,CN(C)C1NC(=O)N(c2cc([N+](=O)[O-])c(Cl)cc2F)C(=O)N1C>>CN(C)C1NC(=O)N(c2cc(N)c(Cl)cc2F)C(=O)N1C,[Fe],CC(=O)O,CCOC(C)=O,,,test
US20090270405A1,Cc1nc(N)nc(Cl)c1C>>Cc1cnc(N)nc1C,[Pd],CO,N,,,test
US20060128639A1,COC(=O)C(F)(F)F.NCCCCCC(=O)O>>CCCCC(NC(=O)C(F)(F)F)C(=O)O,,CCOC(C)=O,CO,CCN(CC)CC,Cl,test
US20090298807A1,OCCCCSCCC1OCCO1>>O=CCCSCCCCO,,O,O=CO,,,test
US20140206681A1,COC[C@H]1CC[C@H](C(=O)OC)CN1C(=O)OCc1ccccc1>>COC[C@H]1CC[C@H](C(=O)O)CN1C(=O)OCc1ccccc1,,C1CCOC1,O,[Li+].[OH-],,test
US20130217680A1,O=C(O)Cc1ccc(-n2cnnn2)cc1.O=C(OCc1ccccc1)N1CC2CC1CN2>>O=C(Cc1ccc(-n2cnnn2)cc1)N1CC2CC1CN2C(=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,ClCCCl,test
US20070203136A1,COc1ccc(CCl)cc1.O=c1nc[nH]c2ccc(I)cc12>>COc1ccc(Cn2cnc3ccc(I)cc3c2=O)cc1,,C1CCOC1,,O,[H-].[Na+],test
US03976672,C=CS(=O)(=O)c1ccc(C)cc1.C[SnH](C)C>>Cc1ccc(S(=O)(=O)CC[Sn](C)(C)C)cc1,,C1CCOC1,,,,test
US20110288066A1,CCCS(=O)(=O)c1ccc(C)c(C#Cc2cc(Cl)ccc2OCOC)c1>>CCCS(=O)(=O)c1ccc(C)c(C#Cc2cc(Cl)ccc2O)c1,,C1COCCO1,,Cl,,test
US05668151,C#CCOc1cccc(C2CCN(CCCNC(=O)Nc3cccc(C4C(C(=O)OC)=C(C)NC(C)=C4C(=O)OC)c3)CC2)c1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc(NC(=O)NCCCN2CCC(c3cccc(OC(C)C)c3)CC2)c1,[Pd],,,CCOC(C)=O,,test
US20050192287A1,CN1CCC(C(=O)O)CC1.NCc1ccc(Oc2ccnc(N)c2)cc1[N+](=O)[O-]>>CNc1ccc(Oc2ccnc(NC(=O)C3CCN(C)CC3)c2)cc1[N+](=O)[O-],,CN(C)C=O,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US20050085482A1,CNC(=O)c1cc(Oc2ccc3nc(S(C)(=O)=O)ncc3c2)ccn1.c1ccc(Nc2ccc3ccccc3c2)cc1>>CNC(=O)c1cc(Oc2ccc3nc(Nc4ccc5ccccc5c4)ncc3c2)ccn1,,CC#N,,,,test
US05648368,CC(C)(C)OC(=O)N1CCC(CCCc2ccc(CO[Si](C)(C)C(C)(C)C)cc2)CC1.O=[Cr](=O)=O>>CC(C)(C)OC(=O)N1CCC(CCCc2ccc(C(=O)O)cc2)CC1,,CC(C)=O,,O=S(=O)(O)O,,test
US20100063077A1,Brc1cnc(Nc2cccc(OCc3ccccc3)c2)nc1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N(c1cccc(OCc2ccccc2)c1)c1ncc(Br)cn1,CN(C)c1ccncc1,C1CCOC1,CCOCC,c1ccncc1,,test
US20160159783A1,C[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1nc2cc(Cl)cc(Br)c2o1.Fc1ccc(B2OB(c3ccc(F)cc3)OB(c3ccc(F)cc3)O2)cc1>>C[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1nc2cc(Cl)cc(-c3ccc(F)cc3)c2o1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,CCO,O,O=C([O-])[O-].[K+].[K+],test
US20070203100A1,Cc1cc(OCc2ccc(C3CCN(CCC(=O)OC(C)(C)C)CC3)cc2)ccc1C1CCSCC1>>Cc1cc(OCc2ccc(C3CCN(CCC(=O)O)CC3)cc2)ccc1C1CCSCC1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20040242600A1,CCOC(=O)c1cc(-c2ccc(C#N)cc2)[nH]c1N.NC=O>>N#Cc1ccc(-c2cc3c(O)ncnc3[nH]2)cc1,,O=CO,,CN(C)C=O,,test
US20050171103A1,Brc1ccccn1.CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(-c2ccccn2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])O.[Na+],,test
US20090275538A1,COC(=O)C1OC(Br)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O.O=C1N=C(N2CCCCN2)S/C1=C\c1ccc(F)cc1O>>COC(=O)C1OC(Oc2cc(F)ccc2/C=C2\SC(N3CCCCN3)=NC2=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080214598A1,CC(C)(C)[SiH2]OC(C)(C)c1cc(CNC(=O)CC(F)(F)F)ccc1Cl>>O=C(CC(F)(F)F)NCc1ccc(Cl)c(CO)c1,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100056791A1,CCOC(=O)c1ccc(OC)n2nc(C(F)(F)F)c(Cl)c12>>COc1ccc(C(=O)O)c2c(Cl)c(C(F)(F)F)nn12,,CO,,[K+].[OH-],,test
US20140275083A1,COC(=O)c1cc(N2C(=O)OC[C@@H]2[C@@H](C)OC(C)(C)C)nc(Cl)n1>>C[C@@H](OC(C)(C)C)[C@H]1COC(=O)N1c1cc(CO)nc(Cl)n1,,CO,,[BH4-].[Na+],,test
US20130045986A1,Nc1ccc(Br)cc1N.O=C(O)C1CCNCC1>>Brc1ccc2[nH]c(C3CCNCC3)nc2c1,,O,,[Na+].[OH-],,test
US20110237791A1,COc1nc(C(O)c2ccc(C(C)(C)C)cc2)ccc1Cl.OCC1CCCC1>>COc1nc(C(OCC2CCCC2)c2ccc(C(C)(C)C)cc2)ccc1Cl,Cl[Pd]Cl,ClCCCl,,O,,test
US08003783B2,C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=O.N#Cc1ccc(C=O)cc1>>CC12CCC3c4ccc(O)cc4CCC3C1CC(=Cc1ccc(C#N)cc1)C2=O,,CCO,O,CC(=O)O,[K+].[OH-],test
US20100261709A1,Cc1cccc(C#N)n1>>C[C@@H]1CCC[C@H](CN)N1,O=[Pt]=O,O=C(O)C(F)(F)F,,,,test
US20040209892A1,CN1CCN(Cc2cc(N=C=S)ccc2Cl)CC1.CNc1nccc(Oc2ccc(N)c(N)c2)n1>>CNc1nccc(Oc2ccc3[nH]c(Nc4ccc(Cl)c(CN5CCN(C)CC5)c4)nc3c2)n1,,CC#N,,ClCCCl,,test
US20160221994A1,C/C=C/C(=O)Cl.CC(=O)c1ccc(-c2cc(Cl)c3c(c2)CC(CN)O3)s1>>C/C=C/C(=O)NCC1Cc2cc(-c3ccc(C(C)=O)s3)cc(Cl)c2O1,,ClCCl,,CCN(CC)CC,O,test
US20100152160A1,CCOC(=O)C(Br)C(=O)OCC.O=[N+]([O-])c1cc(Cl)ccc1O>>CCOC(=O)C(Oc1ccc(Cl)cc1[N+](=O)[O-])C(=O)OCC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04094886,C=CCCC(=O)CC(=O)OC.Cc1ccc(S(=O)(=O)N=[N+]=[N-])cc1>>C=CCCC(=O)C(=[N+]=[N-])C(=O)OC,,CC#N,,CCN(CC)CC,,test
US20040260088A1,Br.CCSc1c(CN(C)C)cccc1OC>>Br.CCSc1c(O)cccc1CN(C)C,,CCOCC,,CC(=O)O,,test
US20090098086A1,C1CC2CNCC1O2.CNN.O=Cc1c(Cl)nc(Cl)nc1Cl>>Cn1ncc2c(N3CC4CCC(C3)O4)nc(Cl)nc21,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20090306016A1,BrCCCCCCCc1ccccc1OCc1ccccc1.O=S([O-])[O-].[Na+]>>O=S(=O)([O-])CCCCCCCc1ccccc1OCc1ccccc1.[Na+],,O,,CCO,,test
US20130085141A1,COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)CCl.NCc1ccccc1>>O=C1[C@@H]2C[C@@H](O)CN2C(=O)CN1Cc1ccccc1,,CCOCCO,,CCN(CC)CC,,test
US20100121048A1,CCN=C=NCCCN(C)C.Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@H]2CN2CCC(C(=O)O)CC2)c(-c2ccccc2)n1-c1ccccc1>>Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@H]2CN2CCC(C(N)=O)CC2)c(-c2ccccc2)n1-c1ccccc1,,CN(C)C=O,,Cl,O=C([O-])O.[Na+],test
US20060241115A1,COc1cc2nccc(Oc3ccc4c(N)cccc4c3)c2cc1OC.O=C=Nc1ccccc1F>>COc1cc2nccc(Oc3ccc4c(NC(=O)Nc5ccccc5F)cccc4c3)c2cc1OC,,C1CCOC1,,,,test
US20160168148A1,Cc1cc2c(ccc3nnc(C)n32)n1S(=O)(=O)c1ccccc1.O=C1CCC(=O)N1Br>>Cc1cc2c(cc(Br)c3nnc(C)n32)n1S(=O)(=O)c1ccccc1,,ClCCCl,ClCCl,,,test
US20150087646A1,NC(=O)c1ccc(C(F)(F)F)c(F)c1.O=C(Cl)C(=O)Cl>>O=C=NC(=O)c1ccc(C(F)(F)F)c(F)c1,,ClCCCl,,,,test
US20040162321A1,COc1ccc(F)cc1C(C)(C)CC(O)(Cn1ccc(=NC(c2ccccc2)(c2ccccc2)c2ccccc2)c2ccccc21)C(F)(F)F>>COc1ccc(F)cc1C(C)(C)CC(O)(Cn1ccc(=N)c2ccccc21)C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030078289A1,COc1ccc(Oc2c(C)cc([N+](=O)[O-])cc2C)cc1C(=O)N(C)C1CCC1>>CNC(=O)c1ccccc1O,,ClCCl,,BrB(Br)Br,,test
US20110124662A1,COc1nc(C)c(Nc2nc(Cl)cn(C[C@@H](OC)C3CC3)c2=O)cc1C>>COc1nc(C)c(Nc2nc(Cl)cn(C[C@@H](O)C3CC3)c2=O)cc1C,,ClCCl,,BrB(Br)Br,,test
US20100249176A1,CCOC(=O)Cl.O=Cc1ccc2cn[nH]c2c1.[C-]#N>>CCOC(=O)OC(C#N)c1ccc2cn[nH]c2c1,,CCO,,O,,test
US20150307493A1,CNC.O=[N+]([O-])c1cc(S(=O)(=O)Cl)ccc1O>>CN(C)S(=O)(=O)c1ccc(O)c([N+](=O)[O-])c1,,C1CCOC1,C1CCOC1,,,test
US07582785B2,CC[C@H](/C=C/C#CC[C@H](/C=C/C=C/C#C[C@H](CCCC(=O)OC)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C>>CC[C@@H](O)/C=C/C#CC[C@@H](O)/C=C/C=C/C#C[C@@H](O)CCCC(=O)OC,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20110009354A1,CCOC(=O)CCCl.CNC[C@H]1O[C@@H](n2c(C)nc3c(N)ncnc32)[C@H](O)[C@@H]1O>>CCOC(=O)CCN(C)C[C@H]1O[C@@H](n2c(C)nc3c(N)ncnc32)[C@H](O)[C@@H]1O,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20140155375A1,Cc1cc(Cl)c2c(I)cn(C)c2n1.OB(O)c1cccc(N2CCCC2)c1>>Cc1cc(Cl)c2c(-c3cccc(N4CCCC4)c3)cn(C)c2n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20150225371A1,Cc1cc(-c2cn(CCN3CCC3)c(C3CCN(c4ncnc(N)c4C(C)C)CC3)n2)ccc1F.Cl>>Cc1cc(-c2cn(CCNCCCCl)c(C3CCN(c4ncnc(N)c4C(C)C)CC3)n2)ccc1F,,CO,,C1COCCO1,,test
US20120329780A1,CC(=O)N1CCN(c2ccc(N)cc2)CC1.COc1ccc(Cn2cc3nc(-c4cnc5cc[nH]c5c4)nc(Cl)c3n2)cc1>>CC(=O)N1CCN(c2ccc(Nc3nc(-c4cnc5cc[nH]c5c4)nc4cn[nH]c34)cc2)CC1,C1COCCO1,CO,,Cl,,test
US05488055,CCn1nccc1Nc1cc(C(=O)O)ccc1C(=O)O.O=P(Cl)(Cl)Cl>>CCn1ncc2c(Cl)c3ccc(C(=O)O)cc3nc21,,CC(=O)O,,O,,test
US20120277325A1,CC1(C)CCC(C)(C)C2=C1CCCC2=O.CCCCO.N=CN>>CC1(C)CCC(C)(C)C2=C1CCc1cncnc12,,CCCCO,,CC(=O)O,,test
US04051248,Cc1cc2c(cc1C)CCC(CN1CCC3(CC1)C(=O)NCN3c1ccccc1)=C2.Cl>>Cc1cc2c(cc1C)CCC(CN1CCC3(CC1)C(=O)NCN3c1ccccc1)=C2.Cl,,CCO,,,,test
US20080139616A1,CC(C)N1C(=O)C(NC2CCN(c3ncc(C(F)(F)F)cc3Cl)CC2)=C(c2ccccc2)S1(=O)=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)N1C(=S)C(NC2CCN(c3ncc(C(F)(F)F)cc3Cl)CC2)=C(c2ccccc2)S1(=O)=O,,Cc1ccccc1,,,,test
US20150238498A1,CCOC(=O)CNC(=O)c1ccc(OCCO)c(OC)c1>>COc1cc(C(=O)NCC(=O)O)ccc1OCCO,,CCO,O,[K+].[OH-],,test
US20150057265A1,CC(C)(C)OC(=O)N1[C@@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@H](CO)C(F)(F)F)COC1(C)C.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>CC(C)(C)OC(=O)N1[C@@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@H](CN=[N+]=[N-])C(F)(F)F)COC1(C)C,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050075347A1,O=C(Cl)CCl.c1cnc(N2CCNCC2)nc1>>O=C(CCl)N1CCN(c2ncccn2)CC1,,ClCCl,,CCN(CC)CC,O,test
US05914328,CC(C)(C)OC(=O)N1CCC[C@@H]1CO.Oc1cnc2ccccc2c1>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1cnc2ccccc2c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020035266A1,COC(=O)/C(=C/CC1CCCC1)c1ccc(-n2nnnc2C)c(C(F)(F)F)c1>>Cc1nnnn1-c1ccc(/C(=C\CC2CCCC2)C(=O)O)cc1C(F)(F)F,,CCO,,[Na+].[OH-],,test
US20100093706A1,COC(=O)C1CNCCC1C>>COC(=O)C1CNCCC1C,,ClCCl,,Cl,O=C([O-])[O-].[K+].[K+],test
US20110237573A1,Cc1cc(CC(=O)O)cnc1-c1ccnc(F)c1.Nc1ccc(-c2cnccn2)cn1>>Cc1cc(CC(=O)Nc2ccc(-c3cnccn3)cn2)cnc1-c1ccnc(F)c1,,ClCCl,,CC(C)N=C=NC(C)C,,test
US20090209607A1,CC(C)(C)OC(=O)N[C@@H](Cc1c(F)cccc1F)CN1C(=O)c2ccccc2C1=O>>N[C@@H](Cc1c(F)cccc1F)CN1C(=O)c2ccccc2C1=O,,CO,ClC(Cl)Cl,C1COCCO1,Cl,test
US20050209254A1,Cc1ccc(C(=O)N(CCCNC(=O)OC(C)(C)C)C(C(=O)N(C)C)c2nc3cc(Cl)ccc3c(=O)n2Cc2cccc(C)c2)cc1>>Cc1ccc(C(=O)N(CCCN)C(C(=O)N(C)C)c2nc3cc(Cl)ccc3c(=O)n2Cc2cccc(C)c2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090312310A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@H]1CN(C(=O)OCc2ccccc2)C[C@@H]1N>>CC(C)(C)OC(=O)N[C@H]1CN(C(=O)OCc2ccccc2)C[C@@H]1N,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20090054475A1,CC(C)(C)OC(=O)N1CCC(c2nc(CCl)cs2)CC1.CS(=O)(=O)c1ccc(O)cc1>>CC(C)(C)OC(=O)N1CCC(c2nc(COc3ccc(S(C)(=O)=O)cc3)cs2)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20010025045A1,CI.O=C1NC(=O)c2c1cccc2[N+](=O)[O-]>>CN1C(=O)c2cccc([N+](=O)[O-])c2C1=O,,CN(C)C=O,,[H-].[Na+],,test
US20100035883A1,Nc1cc(F)cc2c1COC2=O.O=Cc1ccccc1>>O=C1OCc2c(/N=C/c3ccccc3)cc(F)cc21,,CC#N,,O=S(=O)([O-])[O-].[Mg+2],,test
US20030119885A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(S(=O)(=O)N[C@@H]2CCC[C@H]2NCCCc2ccc(Cl)cc2)cc1>>CC(C)(C)OC(=O)N(CCCc1ccc(Cl)cc1)[C@@H]1CCC[C@H]1NS(=O)(=O)c1ccc([N+](=O)[O-])cc1,,ClCCl,,CCN(CC)CC,,test
US20150284394A1,Cc1ccc(B(O)O)cc1Cl.Cc1ccc(S(=O)(=O)n2ccc3c(Cl)ncnc32)cc1>>Cc1ccc(-c2ncnc3[nH]ccc23)cc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,O,COCCOC,O=C([O-])[O-].[K+].[K+],test
US05789415,CCCCc1nc(Cl)c(C(=O)OCC)n1Cc1ccc(C2(C(=O)OCC)CC=CC2)s1>>CCCCc1nc(Cl)c(C(=O)O)n1Cc1ccc(C2(C(=O)O)CC=CC2)s1,,CO,,[Na+].[OH-],,test
US05948793,CN1CCC[C@H]1COc1cccnc1.O=C(O)/C=C/C(=O)O>>CN1CCC[C@H]1COc1cccnc1.O=C(O)/C=C/C(=O)O,,CO,,,,test
US06455520B1,C1COCCN1.CCN(CC)Cc1ccc(C(=O)Nc2cc(NC(=O)c3ccnc(Cl)c3)ccc2C)cc1>>CCN(CC)Cc1ccc(C(=O)Nc2cc(NC(=O)c3ccnc(N4CCOCC4)c3)ccc2C)cc1,,O,,,,test
US20130045942A1,COc1cccc([C@H](C)N)c1.OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O>>COc1cccc([C@H](C)Nc2ncnc3c2ncn3[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1,,CCCO,,,,test
US20150051395A1,CCNC(=O)c1ccc(S(=O)(=O)Nc2cc(F)c(C(=O)O)c(F)c2)cc1.COC(=O)[C@@H](N)Cc1ccc(-n2c(=O)ccn(C)c2=O)cc1>>CCNC(=O)c1ccc(S(=O)(=O)Nc2cc(F)c(C(=O)N[C@@H](Cc3ccc(-n4c(=O)ccn(C)c4=O)cc3)C(=O)O)c(F)c2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060014827A1,OCc1cccc(C2=CCCC2)c1>>O=Cc1cccc(C2=CCCC2)c1,O=[Mn]=O,ClC(Cl)Cl,,,,test
US20120040954A1,C1CCNC1.COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCBr)cc3)nc2c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCN4CCCC4)cc3)nc2c1,,CN(C)C=O,,,,test
US05401772,CC(O)(C(=O)O)c1ccccc1.CCO>>CCOC(=O)C(C)(O)c1ccccc1,,CCOCC,,O=S(=O)(O)O,,test
US20020156054A1,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2ccc(O[Si](C)(C)CC(C)C)cc2)=CCC3(C)C)cc1>>CC1(C)CC=C(c2ccc(O)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20130217680A1,CC(C)(C)OC(=O)N1CCNCC1.COc1c(Br)ccc2c1CCOC2C=O>>COc1c(Br)ccc2c1CCOC2CN1CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20080293753A1,Brc1ccc(OCc2ccccc2)cc1.COC(=O)[C@@H]1CCC(=O)N1C(=O)OC(C)(C)C>>COC(=O)[C@H](CCC(=O)c1ccc(OCc2ccccc2)cc1)NC(=O)OC(C)(C)C,,C1CCOC1,,[Li]CCCC,,test
US20150011533A1,Nc1c[nH]c2ncc(Cl)cc12.O=C(O)c1cnn(Cc2ccccc2)c1>>O=C(Nc1c[nH]c2ncc(Cl)cc12)c1cnn(Cc2ccccc2)c1,,CC#N,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060040961A1,CN[C@@H]1CCCO1.Clc1ncnc2oc(I)c(-c3ccccc3)c12>>Ic1oc2ncnc(NC[C@@H]3CCCO3)c2c1-c1ccccc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,,test
US20160168090A1,Cl.N#CC1(c2ccccc2)CCCCC1>>Cl.NCC1(c2ccccc2)CCCCC1,[Ni],CO,,,,test
US20110021498A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(OCc1ccccc1)c1ccc2[nH]ccc2c1>>CC(C)(C)OC(=O)n1ccc2cc(C(=O)OCc3ccccc3)ccc21,CN(C)c1ccncc1,CC#N,,,,test
US20160272617A1,Cc1cc(C(=O)NCCCN(C)C)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1.Cl>>Cc1cc(C(=O)NCCCN(C)C)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1.Cl,,C1COCCO1,,O=C(O)C(F)(F)F,,test
US20050032786A1,N#Cc1ccccn1.O=C(O)c1ccc(Cl)cc1S>>O=c1nc(-c2ccccn2)sc2cc(Cl)ccc12,,c1ccncc1,,,,test
US20100168136A1,COc1ccc(CSC(c2cnc(Br)cc2C)c2c(F)ccc(F)c2F)cc1>>Cc1cc(Br)ncc1C(S)c1c(F)ccc(F)c1F,,CCCCCC,CCOC(C)=O,O=C(O)C(F)(F)F,,test
US20090118327A1,O=[N+]([O-])c1ccc(C(CN=C=S)c2cccc(Cl)c2)cc1>>O=[N+]([O-])c1ccc(C2CN=C(S)c3ccc(Cl)cc32)cc1,,ClCCl,,O=S(=O)(O)O,,test
US20120264700A1,CCc1ccc([C@@H]2O[C@H](COP(=O)(OC(C)(C)C)OC(C)(C)C)[C@@H](O)[C@H](O)[C@H]2O)cc1Cc1ccc2c(c1)OCCO2>>CCc1ccc([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O)[C@H]2O)cc1Cc1ccc2c(c1)OCCO2,,CO,,,,test
US20150119435A1,NCCOCCN.O=C(O)CC12CC3CC(CC(C3)C1)C2>>NCCOCCNC(=O)CC12CC3CC(CC(C3)C1)C2,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20110319449A1,COc1cc(-n2ccc(Cl)cc2=O)ccc1OCC(C)(C)O.OB(O)c1ccc(OC(F)(F)F)cc1>>COc1cc(-n2ccc(-c3ccc(OC(F)(F)F)cc3)cc2=O)ccc1OCC(C)(C)O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,ClCCl,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20040005986A1,COC(=O)Oc1ccc(F)cc1Br.O=[N+]([O-])O>>COC(=O)Oc1cc([N+](=O)[O-])c(F)cc1Br,,O=S(=O)(O)O,,,,test
US20130059883A1,CC(C)(CCl)OCCCl.N#CCc1nc(-c2ccc(F)cc2)cs1>>CC1(C)CC(C#N)(c2nc(-c3ccc(F)cc3)cs2)CCO1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US06878728B1,CC(C)CN(C[C@@H](O)[C@H](Cc1ccc(O)cc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc2c(c1)OCO2.CCOC(=O)CBr>>CCOC(=O)COc1ccc(C[C@H](NC(=O)O[C@H]2CO[C@H]3OCC[C@@H]23)[C@H](O)CN(CC(C)C)S(=O)(=O)c2ccc3c(c2)OCO3)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100292238A1,COc1ccc(C2=CC(=O)C(C)(C)O2)cc1.O=C1CCC(=O)N1Br>>COc1ccc(C2=C(Br)C(=O)C(C)(C)O2)cc1,,ClC(Cl)Cl,ClCCl,,,test
US20050054670A1,CC1c2cccc(N)c2C(=O)N1c1ccc(C(C)(C)C)cc1.O=Cc1ccncc1>>CC1c2cccc(NCc3ccncc3)c2C(=O)N1c1ccc(C(C)(C)C)cc1,,CCOC(C)=O,ClCCCl,Cl,O=C([O-])O.[Na+],test
US20120165335A1,CC(=O)O.Nc1ccccc1N>>CC(=O)Nc1ccccc1N,CN(C)c1ccncc1,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US03951988,CCOC(=O)C=C1NCCN1.CCOC(=O)CC(C)=O.O=Cc1ccccc1>>CCOC(=O)C1=C(C)N2CCNC2=C(C(=O)OCC)C1c1ccccc1,,CCO,,,,test
US20080125398A1,CCN(CC)CCS.O=P(OCCOS(=O)(=O)c1ccc(Br)cc1)(N(CCCl)CCCl)N(CCCl)CCCl>>CCN(CC)CCSCCOP(=O)(N(CCCl)CCCl)N(CCCl)CCCl,,CO,,Cl,[Na+].[OH-],test
US20150266867A1,N=C(N)n1cccn1.NC[C@@H]1CN(C[C@@H]2[C@H](NC(=O)/C(=N\OC3(C(=O)O)CC3)c3csc(N)n3)C(=O)N2S(=O)(=O)O)C(=O)O1>>N=C(N)NC[C@@H]1CN(C[C@@H]2[C@H](NC(=O)/C(=N\OC3(C(=O)O)CC3)c3csc(N)n3)C(=O)N2S(=O)(=O)O)C(=O)O1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20100113546A1,CCc1c(C2=NCC(=O)N2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1.CI>>CCc1c(C2=NCC(=O)N2C)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20150126449A1,CC1CC(c2cc(=O)[nH]c3c4c(Br)cccc4nn23)CCN1C(=O)OC(C)(C)C.Cl>>C[C@H]1C[C@H](c2cc(=O)[nH]c3c4c(Br)cccc4nn23)CCN1.Cl,,C1COCCO1,CO,,,test
US20130045986A1,O=C(Nc1cc(Br)ccc1O)C1CCN(Cc2ccccc2)CC1>>Brc1ccc2oc(C3CCN(Cc4ccccc4)CC3)nc2c1,,Cc1ccccc1C,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040110804A1,CC(C)(C)OC(=O)CON(Cc1ccc(F)cc1)C(=O)C=C1OC(C)(C)OC1=O.CO>>COC(=O)C(O)=CC(=O)N(Cc1ccc(F)cc1)OCC(=O)OC(C)(C)C,,CO,,,,test
US20070249722A1,CCOC(=O)[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)[C@H](C)C(F)(F)F>>C[C@@H]([C@@H](CO)NS(=O)(=O)c1ccc(Cl)cc1)C(F)(F)F,,C1CCOC1,,Cl,[BH4-].[Li+],test
US20150152097A1,CCOC(=O)CC1(c2ccccc2)OCCO1>>O=CCC1(c2ccccc2)OCCO1,,Cc1ccccc1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20160137636A1,COc1cc(Br)c(F)cc1-c1nccc2cc(S(=O)(=O)Oc3c(F)c(F)c(F)c(F)c3F)ccc12.Nc1ccon1>>COc1cc(Br)c(F)cc1-c1nccc2cc(S(=O)(=O)Nc3ccon3)ccc12,,CCOC(C)=O,,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20100249124A1,CI.COc1ccc(CC(=O)c2ccc3oc(=O)n(C)c3c2)c(Cl)c1>>COc1ccc(C(C)C(=O)c2ccc3oc(=O)n(C)c3c2)c(Cl)c1,,CN(C)C=O,,[H-].[Na+],,test
US05622976,Nc1noc(C2CN3CCC2CC3)n1.O=C(Cl)CC1CCN(Cc2ccccc2)CC1>>O=C(CC1CCN(Cc2ccccc2)CC1)Nc1noc(C2CN3CCC2CC3)n1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20020028832A1,CC(C)(C)[Si](Oc1ccc(OC[C@@H](O)CNCCc2ccc(NC3CCN(C(=O)NCc4ccc(F)cc4)CC3)cc2)cc1)(c1ccccc1)c1ccccc1>>O=C(NCc1ccc(F)cc1)N1CCC(Nc2ccc(CCNC[C@H](O)COc3ccc(O)cc3)cc2)CC1,,CO,ClC(Cl)Cl,,,test
US20080139639A1,CN.Cl.O=Cc1cn(S(=O)(=O)c2ccccc2)c(-c2ccccc2)c1F>>CNCc1cn(S(=O)(=O)c2ccccc2)c(-c2ccccc2)c1F.Cl,,CO,,[BH4-].[Na+],,test
US20020049210A1,CCn1c(C)nc2cc(C(C)=O)ccc21.O=CC1CCN(Cc2ccccc2)CC1>>CCn1c(C)nc2cc(C(=O)C=CC3CCN(Cc4ccccc4)CC3)ccc21,,C1CCOC1,O,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20130296301A1,C=CCN(C(=O)OC(C)(C)C)C1=N[C@H]2[C@H](O[C@H](C(C)O)[C@@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)S1>>C=CCN(C(=O)OC(C)(C)C)C1=N[C@H]2[C@H](O[C@H](C(C)=O)[C@@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)S1,,ClCCl,,,,test
US05668154,COC(=O)CBr.c1ccc2c(Nc3ccncc3)noc2c1>>Br.COC(=O)Cn1ccc(=Nc2noc3ccccc23)cc1,,CC#N,,,,test
US20040054179A1,COc1ccc(-c2cc3nccn3c(Cl)n2)cc1OC.Fc1ccc(N2CCNCC2)cc1>>COc1ccc(-c2cc3nccn3c(N3CCN(c4ccc(F)cc4)CC3)n2)cc1OC,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20160130237A1,CN(C)CCCN.Clc1cc(Cl)ncn1>>CN(C)CCCNc1cc(Cl)ncn1,,CC(C)O,,CCN(C(C)C)C(C)C,O,test
US04088646,O=C(Br)c1ccccc1.O=C(c1ccccc1)n1c(=O)[nH]cc(F)c1=O.O=c1[nH]cc(F)c(=O)[nH]1>>O=C(c1ccccc1)n1cc(F)c(=O)n(C(=O)c2ccccc2)c1=O,,c1ccncc1,,,,test
US20150175541A1,CNC.Cc1ccc(S(=O)(=O)OC[C@H](CC#N)NC(=O)OC(C)(C)C)cc1>>CN(C)C[C@H](CC#N)NC(=O)OC(C)(C)C,,CCO,,CCN(CC)CC,,test
US20090221555A1,CCN1CCc2ccc(N)cc2CC1.CNC(=O)CCNc1nc(Cl)ncc1Cl>>CCN1CCc2ccc(Nc3ncc(Cl)c(NCCC(=O)NC)n3)cc2CC1,,CC(C)O,,C1COCCO1,Cl,test
US20070149561A1,CCn1cc(-c2ccnc3[nH]c(-c4ccc5c(c4)CN(C(C)=O)CC5)cc23)c(-c2ccc(NC(=O)N(C)C)cc2)n1>>CCn1cc(-c2ccnc3[nH]c(-c4ccc5c(c4)CNCC5)cc23)c(-c2ccc(NC(=O)N(C)C)cc2)n1,,CCO,,,,test
US20100292255A1,CC(=O)O[C@@H](C)C(=O)Cl.C[C@@H](N)C(=O)N1CCC(Cn2c(Sc3cc4c(cc3Br)OCCO4)nc3c(N)ncnc32)CC1>>CC(=O)O[C@@H](C)C(=O)N[C@H](C)C(=O)N1CCC(Cn2c(Sc3cc4c(cc3Br)OCCO4)nc3c(N)ncnc32)CC1,,C1CCOC1,,,,test
US06204215B1,BrC1CCCC1.CCCCOC(=O)CC(=O)OCCCC>>CCCCOC(=O)C(C(=O)OCCCC)C1CCCC1,,C1CCOC1,,[H-].[Na+],,test
US04826834,CNC.Clc1ccc2ncnn2n1>>CN(C)c1ccc2ncnn2n1,,CCO,,,,test
US08304419B2,Cc1nc(Cl)c(C(=O)O)[nH]1.N#Cc1ccc(Oc2c(Cl)ccc(CN)c2F)c(F)c1>>Cc1nc(Cl)c(C(=O)NCc2ccc(Cl)c(Oc3ccc(C#N)cc3F)c2F)[nH]1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05530026,Nc1ccc2cn[nH]c2c1.O=C=NCCCl>>O=C(NCCCl)Nc1ccc2cn[nH]c2c1,,CCO,,,,test
US20070249670A1,CC1(C)OB(C2CC2)OC1(C)C.Cc1cc(Br)cc(C)c1NC(=O)C(F)(F)F>>Cc1cc(C2CC2)cc(C)c1NC(=O)C(F)(F)F,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20020013460A1,CNC(=O)c1ccsc1C.COc1ccc(C#N)cc1>>COc1ccc(-c2cc3sccc3c(=O)[nH]2)cc1,,C1CCOC1,,[Li]CCCC,,test
US04179563,O=P(Cl)(Cl)Cl.[O-][n+]1cccc(Oc2ccc(Cl)cc2)c1>>Clc1ccc(Oc2ccc(Cl)nc2)cc1,,Cc1ccccc1,ClC(Cl)Cl,,,test
US05556863,CCCSCCOc1cccc2c(Cl)c(C(=O)CC)cnc12.Cc1ccccc1N>>CCCSCCOc1cccc2c(Nc3ccccc3C)c(C(=O)CC)cnc12,,CC#N,,,,test
US06096771,CC(C)(C)OC(=O)NCCS.Fc1ccc2onc(Cl)c2c1>>CC(C)(C)OC(=O)NCCSc1noc2ccc(F)cc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110190258A1,CO.COC(OC)OC.O=Cc1cc(Br)cnc1Cl>>COC(OC)c1cc(Br)cnc1Cl,,CO,ClCCl,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20080009530A1,CC1(CCBr)OCCO1.CCOC(=O)/C=C/c1ccc(O)cc1Oc1ncc(C(F)(F)F)cc1Cl>>CCOC(=O)/C=C/c1ccc(OCCC2(C)OCCO2)cc1Oc1ncc(C(F)(F)F)cc1Cl,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20100273764A1,COCCOc1ccc(NC(=O)Oc2ccc([N+](=O)[O-])cc2)cc1.COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(Cl)cnc3Nc3ccc(N)nc3)n2)cc1>>COCCOc1ccc(NC(=O)Nc2ccc(Nc3ncc(Cl)cc3-c3nc(C)nc(N(Cc4ccc(OC)cc4)Cc4ccc(OC)cc4)n3)cn2)cc1,,ClCCl,,CCN(CC)CC,,test
US20140038999A1,Cc1cc2c3ccncc3c(=O)n(C)c2cc1OC[C@H](CC(C)C)NC(=O)OC(C)(C)C>>Cc1cc2c3ccncc3c(=O)n(C)c2cc1OC[C@@H](N)CC(C)C,,CO,,C1COCCO1,Cl,test
US04757074,CN1CCNCC1.Clc1ccc(C(Cl)c2cccc(Br)c2)cc1>>CN1CCN(C(c2ccc(Cl)cc2)c2cccc(Br)c2)CC1,,ClCCl,,,,test
US20090099190A1,CCOC(=O)c1cnc(Cl)cc1NC(C)C.CNOC>>CCOC(=O)c1cnc(N(C)OC)cc1NC(C)C,,C1COCCO1,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US04496572,C=O.Cc1c(Br)sc2cc(Br)ccc12>>Cc1c(CO)sc2cc(Br)ccc12,,CCCCCC,CCOCC,O,[Li]CCCC,test
US20040106655A1,Clc1nc2ccccc2[nH]1.O=C1CCC(=O)N1Cl>>Clc1ccc2nc(Cl)[nH]c2c1,,CN(C)C=O,,O,,test
US20030119842A1,CC(=O)Cl.Nc1cnccn1.O=Cc1ccccn1.[C-]#[N+]C1CCCCC1>>CC(=O)[n+]1c(-c2ccccn2)c(NC2CCCCC2)n2ccncc21.[Cl-],,[O-][Cl+3]([O-])([O-])O,,,,test
US20150274704A1,Cc1cc(Nc2ncc(Cl)c(NC3CCC4(CCNCC4)CC3)n2)nn1C.N#CCC(=O)O>>Cc1cc(Nc2ncc(Cl)c(NC3CCC4(CC3)CCN(C(=O)CC#N)CC4)n2)nn1C,,CN(C)C=O,ClCCl,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140323518A1,C=Cc1c(C#N)cc(CCC)cc1-c1ccc(O)cc1.NO>>C=Cc1c(C(N)=NO)cc(CCC)cc1-c1ccc(O)cc1,,CS(C)=O,,,,test
US20020032184A1,CCc1nn(CO)c(CC)c1Cc1cc(Cl)cc(Cl)c1.O=C=NC(=O)C(Cl)(Cl)Cl>>CCc1nn(COC(N)=O)c(CC)c1Cc1cc(Cl)cc(Cl)c1,,ClCCl,,,,test
US20110028450A1,COc1cc2c(cc1Br)C1=C(c3cccs3)C3CSCCN(C(C)(C)C)C(=O)C3N1CC2.OB(O)c1cccnc1>>COc1cc2c(cc1-c1cccnc1)C1=C(c3cccs3)C3CSCCN(C(C)(C)C)C(=O)C3N1CC2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20040063646A1,CCSc1ccc(Cc2c(O[C@@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)n[nH]c2C)cc1>>CCSc1ccc(Cc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)n[nH]c2C)cc1,,CO,,C[O-].[Na+],,test
US20030207868A1,C=C(C)n1c(=O)[nH]c2ccccc21.COC(=O)CBr>>C=C(C)n1c(=O)n(CC(=O)OC)c2ccccc21,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US06159904,CC(=O)Cl.COCC1CCSc2c(C)ccc(C)c21>>COCC1CCSc2c(C)cc(C(C)=O)c(C)c21,,CC(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120041004A1,Cc1c[nH]c2c(=O)n(C)c(=O)n(C)c12.O=C(CBr)Nc1nc(-c2cc(F)c(OCc3ccc(C(F)(F)F)cc3)c(F)c2)cs1>>Cn1c(=O)c2c(ccn2CC(=O)Nc2nc(-c3cc(F)c(OCc4ccc(C(F)(F)F)cc4)c(F)c3)cs2)n(C)c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20140343038A1,CC(C)(C)n1cc2ccc([N+](=O)[O-])cc2n1>>CC(C)(C)n1cc2ccc(N)cc2n1,[Pd],CCOC(C)=O,,,,test
US20090197825A1,CCOC(=O)C(C)(C)Sc1nnc(N)n1-c1ccc(C2CC2)c2ccccc12>>CC(C)(Sc1nnc(N)n1-c1ccc(C2CC2)c2ccccc12)C(=O)O,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20050032786A1,CC(C)(C)OC(=O)c1cccc(-c2nc(=O)c3ccccc3s2)n1>>O=C(O)c1cccc(-c2nc(=O)c3ccccc3s2)n1,,O=C(O)C(F)(F)F,,CC(C)OC(C)C,,test
US04105652,CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccccc1)C(=O)OCc1ccccc1.NN>>CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccccc1)C(=O)NN,,CN(C)C=O,,,,test
US20150112067A1,CC(=O)C(CC(N=C(c1ccccc1)c1ccccc1)C(=O)OC(C)C)c1c(F)ccc(F)c1F.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(=O)C(CC(NC(=O)OC(C)(C)C)C(=O)OC(C)C)c1c(F)ccc(F)c1F,,C1CCOC1,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080242677A1,COC(=O)C1CN1S(=O)(=O)c1cccc(OC)c1.O=C=Nc1ccccc1>>COC(=O)C1CN(S(=O)(=O)c2cccc(OC)c2)C(=O)N1c1ccccc1,,C1CCOC1,CCOC(C)=O,[I-].[Na+],,test
US20060205718A1,CCI.O=Cc1cc(O)c(O)c(O)c1>>CCOc1cc(C=O)cc(O)c1O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04140775,COc1cccc(N2CCNCC2)c1.O=[N+]([O-])c1ccc(CCl)cc1>>COc1cccc(N2CCN(Cc3ccc([N+](=O)[O-])cc3)CC2)c1,,CCN(CC)CC,,Cl,Cl,test
US20080182802A1,CCc1ccc(C(=O)Cl)cc1.COc1cc(Cl)ccc1Br>>CCc1ccc(C(=O)c2cc(Br)c(OC)cc2Cl)cc1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20090018132A1,C=O.CC(OCC1(c2ccccc2)CCNCC1)c1cc(C(F)(F)F)cc2cn[nH]c12>>CC(OCC1(c2ccccc2)CCN(C)CC1)c1cc(C(F)(F)F)cc2cn[nH]c12,CC(=O)O,CC#N,,[BH3-]C#N.[Na+],,test
US20130005719A1,CC(O)/C=C/c1ccc(C(F)(F)C(O)(Cn2cnnn2)c2ccc(F)cc2F)nc1>>CC(O)CCc1ccc(C(F)(F)C(O)(Cn2cnnn2)c2ccc(F)cc2F)nc1,[Pd],CO,,,,test
US20090105219A1,COC(=O)Cn1c(=O)n(CC(=O)OC)c2c([N+](=O)[O-])cccc21>>COC(=O)Cn1c(=O)n2c3c(cccc31)NC(=O)C2,[Pd],CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US03970454,CCCc1ccc2c(c1O)N(C)CC=C2>>CCCc1ccc2c(c1O)N(C)CCC2,[Ni],O,,[H][H],,test
US05552409,CN(C)C=C(C=O)c1ccc(Cl)cc1.NC(N)=O>>O=c1ncc(-c2ccc(Cl)cc2)c[nH]1,,CCO,O,Cl,[Cl-].[NH4+],test
US20140206682A1,Cn1nccc1-c1ccn2c(C(=O)Nc3cc(C(=O)O)ccc3F)cnc2c1.N[C@H](CO)[C@H](O)c1ccccc1>>Cn1nccc1-c1ccn2c(C(=O)Nc3cc(C(=O)N[C@H](CO)[C@H](O)c4ccccc4)ccc3F)cnc2c1,,ClCCl,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110257238A1,CCN(CC)Cc1ccc2c(n1)COC2=O.O=C1Cc2cc(F)ccc2N1>>CCN(CC)Cc1ccc2c(n1)COC2=C1C(=O)Nc2ccc(F)cc21,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20120238569A1,CCc1cc(C(=O)NCc2cccc3[nH]ncc23)sc1C(=O)N[C@@H](CNC(=O)c1cccs1)C(=O)OC>>CCc1cc(C(=O)NCc2cccc3[nH]ncc23)sc1C(=O)N[C@@H](CNC(=O)c1cccs1)C(=O)O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20040010037A1,CC1CN(C(=O)OC(C)(C)C)CCN1c1ccc(C#N)c(C(F)(F)F)c1>>CC1CNCCN1c1ccc(C#N)c(C(F)(F)F)c1,,O=C(O)C(F)(F)F,,,,test
US04412079,CCNC(=S)NN.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCNC(=S)NNC(=O)C(F)(F)F,,c1ccccc1,,,,test
US20110092717A1,CCN(CC)CCN.Cc1[nH]c(C=O)c(C)c1C(=O)O>>CCN(CC)CCNC(=O)c1c(C)[nH]c(C=O)c1C,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20070117845A1,CCC(=O)CC(=O)OC.FC(F)(F)c1cnc(Cl)c(Cl)c1>>CCC(=O)C(C(=O)OC)c1ncc(C(F)(F)F)cc1Cl,,CN(C)C=O,,[K+].[OH-],,test
US04892578,CC1(C)CON(Cc2ccc(NC(=O)c3ncccc3C(=O)O)cc2Cl)C1=O>>CC1(C)CON(Cc2ccc(N3C(=O)c4cccnc4C3=O)cc2Cl)C1=O,,CC(=O)OC(C)=O,,CC(=O)[O-].[Na+],,test
US20130184459A1,Cl.Nc1cccc(-c2nc(=O)[nH]c3c2ccc2ccccc23)c1>>Cl.Nc1cccc(-c2nc(=O)[nH]c3c2ccc2ccccc23)c1,,CCOC(C)=O,ClC(Cl)Cl,CO,,test
US04788196,CC(=O)OC(C)=O.Nc1ccc(N2CCN(c3ccncc3)CC2)cc1>>CC(=O)Nc1ccc(N2CCN(c3ccncc3)CC2)cc1,,ClCCl,,,,test
US20100204196A1,COc1cc2c(cc1[N+](=O)[O-])C(=O)NCC2>>COc1cc2c(cc1[N+](=O)[O-])CNCC2,,C1CCOC1,,CO,,test
US20020193596A1,Cc1ccc([N+](=O)[O-])cc1Br.OB(O)Oc1ccccc1>>Cc1ccc([N+](=O)[O-])cc1-c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,Cl,,test
US20050004134A1,CCOC(=O)c1nc(-c2ccccc2)c(-c2ccc(=O)n(C)n2)s1.NCc1ccccn1>>Cn1nc(-c2sc(C(=O)NCc3ccccn3)nc2-c2ccccc2)ccc1=O,,C1COCCO1,,,,test
US04942246,CO.CS(=O)(=O)c1ccc(Br)c(Cl)c1CBr>>COCc1c(S(C)(=O)=O)ccc(Br)c1Cl,,CO,,C[O-].[Na+],,test
US20060258666A1,C[Sn](C)(C)N=[N+]=[N-].N#CCc1ccc(N)c(C2=CCCCC2)c1>>Nc1ccc(Cc2nnn[nH]2)cc1C1=CCCCC1,,Cc1ccccc1,,,,test
US04603018,ON=Cc1cc(F)ccc1O>>N#Cc1cc(F)ccc1O,,CC(=O)OC(C)=O,,,,test
US20040097518A1,C[C@H](NC(=O)c1c(CN2CCN(C(=O)OC(C)(C)C)CC2=O)c(-c2ccccc2)nc2ccccc12)C1CCCCC1>>C[C@H](NC(=O)c1c(CN2CCNCC2=O)c(-c2ccccc2)nc2ccccc12)C1CCCCC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20080312255A1,CCOC(=O)CC(=O)c1ncccn1.NC(=O)CCC(=O)NI>>CCOC(=O)C(I)C(=O)c1ncccn1,,CCOC(C)=O,,,,test
US20020137750A1,NCCO.O=C(Cl)c1cc([N+](=O)[O-])ccc1Cl>>O=C(NCCO)c1cc([N+](=O)[O-])ccc1Cl,,ClCCl,,O=C([O-])O.[Na+],,test
US04697030,C=O.CCOP([O-])OCC>>CCOP(=O)(CO)OCC,,CCN(CC)CC,,,,test
US20060094733A1,CC(C)I.Cn1c(=O)[nH]c2nc(Br)n(Cc3c(F)cccc3Cl)c2c1=O>>CC(C)n1c(=O)n(C)c(=O)c2c1nc(Br)n2Cc1c(F)cccc1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100305133A1,CCCN.COC(=O)c1c(OC)ccc2nc(Cl)c(-c3ccccc3)nc12>>CCCNc1nc2ccc(OC)c(C(=O)OC)c2nc1-c1ccccc1,,C1CCOC1,,CCN(CC)CC,,test
US20070185324A1,CNc1ncc2cc(-c3c(C)ccc4c(Nc5ccc6c(c5)N(C(C)=O)CC6(C)C)nccc34)ccc2n1>>CNc1ncc2cc(-c3c(C)ccc4c(Nc5ccc6c(c5)NCC6(C)C)nccc34)ccc2n1,,CCO,,Cl,,test
US20110275627A1,CCOC(=O)C(C)(C)Cc1c(C(=O)c2ccc(Cl)cc2)c2ccc(O)cn2c1C(=O)C(C)(C)C.ClCc1nc2ccccc2s1>>CCOC(=O)C(C)(C)Cc1c(C(=O)c2ccc(Cl)cc2)c2ccc(OCc3nc4ccccc4s3)cn2c1C(=O)C(C)(C)C,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20040063756A1,C1CCOC1.ClCCl.Nc1ccc2cccc(S(=O)(=O)C(F)(F)F)c2n1>>CCCCCCc1cccc2ccc(N)nc12,,C1CCOC1,,,,test
US20090270460A1,Cc1cc(OCc2c(C(C)C)cnn2-c2c(Cl)cccc2Cl)ccc1C(C)C=O>>Cc1cc(OCc2c(C(C)C)cnn2-c2c(Cl)cccc2Cl)ccc1C(C)CO,,C1CCOC1,CO,[BH4-].[Na+],,test
US20050038035A1,CC(C)(C)OC(=O)N1CCN(c2ccc(NC(=O)C3=C(c4ccc(C(F)(F)F)cc4)CCCC3)cc2)CC1>>O=C(Nc1ccc(N2CCNCC2)cc1)C1=C(c2ccc(C(F)(F)F)cc2)CCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US09029536B2,CCOC(=O)C=C(c1ccc(-c2nn(CC)c3cccnc23)cc1)c1nc2ccccc2n1COCC[Si](C)(C)C>>CCOC(=O)CC(c1ccc(-c2nn(CC)c3cccnc23)cc1)c1nc2ccccc2n1COCC[Si](C)(C)C,[Pd],CCO,,,,test
US05041455,CCOc1nsnc1-c1cccnc1.CI>>CCOc1nsnc1-c1ccc[n+](C)c1.[I-],,CC(C)=O,,,,test
US20030199571A1,CC(C)(C)[Si](C)(C)ONC(=O)[C@H](NS(=O)(=O)Cc1ccc2sccc2c1)c1ccccc1>>O=C(NO)[C@H](NS(=O)(=O)Cc1ccc2sccc2c1)c1ccccc1,,C1CCOC1,CCOC(C)=O,,,test
US20110021537A1,CCCCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)OCc2ccccc2)CC1>>CCCCOC(=O)N1CCN(C(=O)[C@@H](N)CCC(=O)OC(C)(C)C)CC1,[Pd],CCO,,,,test
US20130143863A1,CC1(C)COC2(CCCc3c(Br)cncc32)OC1.O=C1NCc2cc(Cl)ccc21>>CC1(C)COC2(CCCc3c(N4Cc5cc(Cl)ccc5C4=O)cncc32)OC1,[Cu]I,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120101100A1,CCCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2nc(C(=O)OCC)c(C(=O)OCC)s2)cn1.NN>>CCCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2nc3c(O)nnc(O)c3s2)cn1,,CO,,Cl,,test
US20150327551A1,Fc1cccnc1.O=C1NCCc2n[nH]cc21>>O=C1NCCc2nn(-c3cccnc3)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20080171769A1,CC(C)(C)OC(=O)NCCN.O=S(=O)(Cl)c1ccccc1Br>>NCCNS(=O)(=O)c1ccccc1Br,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090181963A1,COC(=O)c1cccc(-n2nnc3c(N4CCOCC4)nc(-c4ccc(NC(=O)Nc5ccc(C(=O)NCCN(C)C)cc5)cc4)nc32)c1>>CN(C)CCNC(=O)c1ccc(NC(=O)Nc2ccc(-c3nc(N4CCOCC4)c4nnn(-c5cccc(C(=O)O)c5)c4n3)cc2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20140057937A1,FC(F)(F)c1cn[nH]c1.O=C(CCl)N1CCCc2c1cnn2-c1ccc(F)cc1>>O=C(Cn1cc(C(F)(F)F)cn1)N1CCCc2c1cnn2-c1ccc(F)cc1,,C1CCOC1,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20080188498A1,CC(C)(C)OC(=O)N1CCC(OCc2ccccc2)C1CC(=O)Cn1cnc2cccnc2c1=O>>O=C(CC1NCCC1O)Cn1cnc2cccnc2c1=O,,C1CCOC1,O,CCO,Cl,test
US20050020652A1,CCCn1c(CCCc2ccc(OC(C)(C)C(=O)OCC)cc2)c(C)n(Cc2ccc(C)c(C)c2)c1=O>>CCCn1c(CCCc2ccc(OC(C)(C)C(=O)O)cc2)c(C)n(Cc2ccc(C)c(C)c2)c1=O,,CCO,,Cl,[Na+].[OH-],test
US20160185785A1,O=c1c2cnn(-c3ccc(-c4ccccc4)nc3)c2ncn1CC1(O)CCNCC1>>O=c1[nH]cnc2c1cnn2-c1ccc(-c2ccccc2)nc1,,O=CO,,O=C(O)C(F)(F)F,,test
US20020077479A1,BrP(Br)Br.COc1cc(OC)cc(OC)c1>>COc1cc(OC)c(P(Br)Br)c(OC)c1,,c1ccncc1,,,,test
US04642311,COc1ccc(-c2nc(C)c(NC(C)=O)[nH]2)cc1>>CC(=O)Nc1[nH]c(-c2ccc(O)cc2)nc1C,,ClCCl,,BrB(Br)Br,,test
US20060111375A1,Cc1cc(C(=O)c2nc(C)c(C)s2)oc1C.N>>Cc1cc(O)c(-c2nc(C)c(C)s2)nc1C,,CO,,,,test
US05321029,CC(=O)CCn1cnc2c1c(=O)n(CC1CC1)c(=O)n2CC1CCCCC1>>O=c1c2[nH]cnc2n(CC2CCCCC2)c(=O)n1CC1CC1,,CCO,,[K+].[OH-],,test
US20120245161A1,C1COCCN1.O=C(O)c1cccc2[nH]ccc12>>O=C(c1cccc2[nH]ccc12)N1CCOCC1,,C1CCOC1,,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US20150291655A1,C=C(C)[C@@H]1CC[C@]2(NCCC(C)(C)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(C(=O)OCc7ccccc7)CC6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NCCC(C)(C)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(C(=O)O)CC6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1COCCO1,CCO,[Na+].[OH-],,test
US20110015240A1,CC(=O)Nc1nc(CCc2ccc(CN)cc2)cs1.CC(C)(C)OC(=O)NN.O=C(n1ccnc1)n1ccnc1>>CC(=O)Nc1nc(CCc2ccc(CNC(=O)NNC(=O)OC(C)(C)C)cc2)cs1,,C1CCOC1,,,,test
US05716944,BrP(Br)Br.O=[N+]([O-])c1ccc(CO)s1>>O=[N+]([O-])c1ccc(CBr)s1,,O,,Cc1ccccc1,,test
US20110144136A1,O=C(O)CCCC1CCCN(C(=O)OCc2ccccc2)C1>>O=C(OCc1ccccc1)N1CCCC(CCCCO)C1,,C1CCOC1,,,,test
US20160031811A1,COC(=O)Cc1ccc(CN2C(=O)CC[C@@H]2C(=O)OC(C)(C)C)cc1.COC(=O)c1ccc(C#CCN[C@H](CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)s1>>COC(=O)c1ccc(C#CCN2C(=O)CC[C@@H]2C(=O)OC(C)(C)C)s1,,CCOC(C)=O,,,,test
US20030018034A1,ClCCNCCCl.Nc1cccnc1>>c1cncc(N2CCNCC2)c1,,Cc1ccccc1C,,Cl,,test
US05856503,C=CCN(C)CCCCCCOc1ccc(C(O)(C=C)c2ccc(Br)cc2)c(O)c1>>C=CCN(C)CCCCCCOc1ccc2c(c1)OCC=C2c1ccc(Br)cc1,,Cc1ccccc1C,,O,,test
US20060264432A1,CC(=O)Nc1ccc(C=O)cc1.N#CCC#N>>CC(=O)Nc1ccc(C=C(C#N)C#N)cc1,C1CCNCC1,CCO,,,,test
US06255276B1,CC1=CCCCCCCC(=O)OCCCCC1>>CC1CCCCCCCC(=O)OCCCCC1,[Pd],CCO,,,,test
US20080176846A1,CNC.Cc1ccc(NC(=O)Nc2ccccc2)cc1-c1cc2cnc(Cl)cc2n(C)c1=O>>Cc1ccc(NC(=O)Nc2ccccc2)cc1-c1cc2cnc(N(C)C)cc2n(C)c1=O,,CN1CCCC1=O,CO,,,test
US03936464,C1=C(c2ccccc2)CCNC1.CC(=O)N1CC(CCBr)c2ccccc21>>CC(=O)N1CC(CCN2CC=C(c3ccccc3)CC2)c2ccccc21,,CCC(C)O,,Cl,O=C([O-])O.[Na+],test
US20030092677A1,CC(C)(C)OC(=O)Nc1ccc(C#Cc2ccc(Cl)cc2)cc1N.CC1(C)OC(=O)C=C(c2cccc(C#N)c2)O1>>N#Cc1cccc(C2=Nc3ccc(C#Cc4ccc(Cl)cc4)cc3NC(=O)C2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120316151A1,O=C(C[C@@H]1CCN(C(=O)C2CC2)C1)NNC(=O)Nc1c(F)cc(Br)cc1F>>O=C(C1CC1)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2c(F)cc(Br)cc2F)C1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20040010033A1,COC(=O)c1ccc(CCl)o1.Cc1ccc2c(c1)C(C)(C)CCC2(C)C>>COC(=O)c1ccc(Cc2cc3c(cc2C)C(C)(C)CCC3(C)C)o1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20140088101A1,CN.COC(=O)c1ncc2c(=O)n(Cc3ccccc3)ccc2c1O>>CNC(=O)c1ncc2c(=O)n(Cc3ccccc3)ccc2c1O,,CCO,,CC(=O)O,O,test
US04687815,ClCc1cccc2c1CC2.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>C1=Cc2cc(C[P+](c3ccccc3)(c3ccccc3)c3ccccc3)ccc21.[Cl-],,ClC(Cl)Cl,,CCOCC,,test
US20140038999A1,Cc1nccc2c1c(=O)n(C)c1cc(OC[C@H](CC=C(F)F)NC(=O)OC(C)(C)C)ccc21.O=C1CCC(=O)N1Br>>Cc1nccc2c1c(=O)n(C)c1cc(OC[C@H](CC=C(F)F)NC(=O)OC(C)(C)C)c(Br)cc21,,CC#N,,,,test
US20070049632A1,CC(C)(C)OC(=O)NN(C(=O)C1C(=O)[C@@]2(C)CC[C@@H]1C2(C)C)c1ccc(F)cc1F>>CC1(C)[C@H]2CC[C@]1(C)c1[nH]n(-c3ccc(F)cc3F)c(=O)c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US04808620,CC(C)(C)c1cc(-c2n[nH]c3ncccc23)cc(C(C)(C)C)c1O.CC1(Cl)COC(=O)O1>>CC(C)(C)c1cc(-c2nn(C3(C)COC(=O)O3)c3ncccc23)cc(C(C)(C)C)c1O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150045349A1,CC(C)C(C)n1cc(Br)c2[nH]nc(N)c2c1=O>>CC(C)[C@H](C)n1cc(Br)c2[nH]nc(N)c2c1=O,,CCCCCC,CCO,,,test
US20040248903A1,Cc1ccoc1C(=O)Cc1cccc(Cl)n1.NO>>Cc1ccoc1C(Cc1cccc(Cl)n1)=NO,,CO,,Cl,[Na+].[OH-],test
US06391873B1,CN(C)Cc1nc(-c2ncn3c2CN(C)C(=O)c2c(Cl)cccc2-3)no1.O=C(O)/C=C\C(=O)O>>CN(C)Cc1nc(-c2ncn3c2CN(C)C(=O)c2c(Cl)cccc2-3)no1.O=C(O)/C=C\C(=O)O,,CCO,,,,test
US20120122843A1,Cc1cscn1.O=C(CCl)N1CCOCC1>>Cc1csc(C(=O)CCl)n1,,CCOCC,Cc1ccccc1,[Li]CCCC,,test
US20030220341A1,NC1CCCc2nccnc21.O=CCCCN1C(=O)c2ccccc2C1=O>>O=C1c2ccccc2C(=O)N1CCCCNC1CCCc2nccnc21,,ClCCl,,O=C([O-])O.[Na+],,test
US20070072925A1,CCS(=O)(=O)Cl.Nc1cccc(C#Cc2ccc(OC(F)F)cc2)c1>>CCS(=O)(=O)Nc1cccc(C#Cc2ccc(OC(F)F)cc2)c1,,ClCCl,,O,c1ccncc1,test
US20140121198A1,C=CC#N.C[C@@H](O)c1nc2cnc3ccsc3c2n1[C@H]1CCCNC1>>C[C@@H](O)c1nc2cnc3ccsc3c2n1[C@H]1CCCN(CCC#N)C1,,CC#N,,C1CCC2=NCCCN2CC1,Cl,test
US20140378459A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)OC(=O)c1ccc(C[C@H](NC(=O)OCc2ccccc2)C(=O)O)cc1>>CC(C)(C)OC(=O)c1ccc(C[C@H](NC(=O)OCc2ccccc2)C(=O)OC(C)(C)C)cc1,CN(C)c1ccncc1,C1CCOC1,CC(C)(C)O,O,,test
US20140200222A1,C[Zn]C.O=C(N[C@H]1CCCC[C@@H]1O)c1cc(CN2CCC(F)(c3cc(Cl)ccn3)CC2)c2cccc(F)c2n1>>Cc1ccnc(C2(F)CCN(Cc3cc(C(=O)N[C@H]4CCCC[C@@H]4O)nc4c(F)cccc34)CC2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,CCOC(C)=O,,,test
US20140148437A1,CC(C)(C)OC(=O)Nc1cc(C2CC2)c2[nH]ccc2c1.Cc1ccc(Br)cn1>>Cc1ccc(-n2ccc3cc(NC(=O)OC(C)(C)C)cc(C4CC4)c32)cn1,[Cu]I,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20140336224A1,N#CCCC(c1ccc(Cl)cc1F)c1n[nH]c2c(I)cccc12.OB(O)c1cccnc1>>N#CCCC(c1ccc(Cl)cc1F)c1n[nH]c2c(-c3cccnc3)cccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])O.[Na+],,test
US20050059710A1,O=C(O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F.O=S(Cl)Cl>>O=C(Cl)c1ccc(F)c(F)c1Nc1ccc(I)cc1F,CN(C)C=O,,,,,test
US05122523,BrCc1ccccc1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)C(Cc1ccccc1)P(=O)(OCC)OCC,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20090197871A1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cc(C)cc(C(=O)NCc2ccc(F)c(-c3cccc(C=O)c3)c2)c1.CN1CCNCC1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cc(C)cc(C(=O)NCc2ccc(F)c(-c3cccc(CN4CCN(C)CC4)c3)c2)c1,,CS(C)=O,,CC(=O)O,,test
US20090156619A1,COc1ccc2[nH]c(C)c(CC(=O)N[C@@H](CCCCNC(=O)OCc3ccccc3)c3ncc(-c4ccc5ccccc5c4)[nH]3)c2c1>>COc1ccc2[nH]c(C)c(CC(=O)N[C@@H](CCCCN)c3ncc(-c4ccc5ccccc5c4)[nH]3)c2c1,[Pd],CO,,,,test
US20140371204A1,O=C(O)Cn1ccc2cccnc21.O=C1CCC(=O)N1Cl>>O=C(O)Cn1cc(Cl)c2cccnc21,,CC#N,,,,test
US20140323463A1,CC(C)(O)c1nc(C(N)=O)c(Cl)nc1Cl.Nc1cnn(CCO)c1>>CC(C)(O)c1nc(C(N)=O)c(Nc2cnn(CCO)c2)nc1Cl,,C1COCCO1,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US06316445B1,C=CCC(C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1)c1ccc(Cl)c(Cl)c1.OO>>C=CC[C@H](C(=O)O)c1ccc(Cl)c(Cl)c1,,O,,C1CCOC1,[Li+].[OH-],test
US05409957,CCCCCCCCN.Clc1ccc(OCCBr)c(Cl)c1>>CCCCCCCCNCCOc1ccc(Cl)cc1Cl,,CCO,,O,O=C([O-])[O-].[Na+].[Na+],test
US20140364413A1,CI.COC(=O)C(C)c1ccc(Br)cc1>>COC(=O)C(C)(C)c1ccc(Br)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US03931201,Nc1ccc(Oc2cccc(Cl)n2)cc1.O=C(Cl)Cl>>O=C=Nc1ccc(Oc2cccc(Cl)n2)cc1,,Cc1ccccc1,,,,test
US04098600,CC(N)C(=O)N(c1ccccc1)C(C)C.O=CO>>[C-]#[N+]C(C)C(=O)N(c1ccccc1)C(C)C,,Cc1ccccc1,,,,test
US08436043B2,COC(=O)c1ccc(NC(c2oc3ccc(F)cc3c2C)C2CCCC2)cc1>>Cc1c(C(Nc2ccc(C(=O)O)cc2)C2CCCC2)oc2ccc(F)cc12,,CCO,,C1CCOC1,[Na+].[OH-],test
US05412141,C=C(P(=O)(OCC)OCC)P(=O)(OCC)OCC.CC(=O)c1ccccc1.O=C1CCC(=O)N1Cl>>CCOP(=O)(OCC)C(Cl)(CCC(=O)c1ccccc1)P(=O)(OCC)OCC,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20060160794A1,CN(Cc1ccccc1Cl)C(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1N1CCSCC1.OO>>CN(Cc1ccccc1Cl)C(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1N1CCS(=O)CC1,,CO,,,,test
US20080207634A1,CCOC(C)=O.CN(Cc1cn2c(F)cccc2n1)[C@H]1CCOc2cccnc21.CN1CCCC1=O.NC1CCNCC1>>CN(Cc1cn2c(N3CCC(N)CC3)cccc2n1)[C@H]1CCOc2cccnc21.[NH4+].[OH-],,CCOC(C)=O,CN1CCCC1=O,,,test
US20020165282A1,CCCCCCCN(CCc1ccc(CC(OCC)C(=O)OC)cc1)C(=O)Nc1ccc(OC)cc1OC>>CCCCCCCN(CCc1ccc(CC(OCC)C(=O)O)cc1)C(=O)Nc1ccc(OC)cc1OC,,C1CCOC1,,[Li+].[OH-],,test
US05556864,BrCC1CO1.Cc1cccc(CCCCc2ccccc2O)c1>>Cc1cccc(CCCCc2ccccc2OCC2CO2)c1,,CC(=O)N(C)C,,CC(C)(C)[O-].[K+],,test
US20040152690A1,C[C@@H]1CNCCN1.FC(F)(F)c1cc(Cl)c2nc(Cl)[nH]c2c1>>C[C@@H]1CN(c2nc3cc(C(F)(F)F)cc(Cl)c3[nH]2)CCN1,,CN1CCCC1=O,O,CCN(C(C)C)C(C)C,,test
US05491147,COc1ccc(-c2cnc(C#N)nc2)cc1OC1CCCC1.OO>>COc1ccc(-c2cnc(C(N)=O)nc2)cc1OC1CCCC1,,CCO,O,[Na+].[OH-],,test
US07807712B2,COc1ccc(C=CC(=O)c2ccc(OCC3CO3)cc2)cc1OC.c1ccc(N2CCNCC2)cc1>>COc1ccc(C=CC(=O)c2ccc(OCC(O)CN3CCN(c4ccccc4)CC3)cc2)cc1OC,,CO,,,,test
US20160024079A1,C[Si](C)(C)CCOCCl.N#Cc1cnc2[nH]cnc2c1>>C[Si](C)(C)CCOCn1cnc2cc(C#N)cnc21,,CN(C)C=O,,[H-].[Na+],,test
US20110124634A1,CC(C)(C)[Si](C)(C)OCCBr.COc1c(C)cnc(Cc2c[nH]c3c(Cl)nc(N)nc23)c1C>>COc1c(C)cnc(Cc2cn(CCO[Si](C)(C)C(C)(C)C)c3c(Cl)nc(N)nc23)c1C,,CN(C)C=O,,[H-].[Na+],,test
US20090197880A1,FC(F)(F)CCCI.Oc1ccc(-c2cc(Cn3cc4nc(-c5cccc(F)c5F)nc-4cn3)on2)cc1>>Fc1cccc(-c2nc3cnn(Cc4cc(-c5ccc(OCCCC(F)(F)F)cc5)no4)cc-3n2)c1F,,CS(C)=O,,[H-].[Na+],,test
US20060135785A1,CCOC(=O)C(C#N)c1ccccc1.C[Si](C)(C)N=[N+]=[N-]>>CCOC(=O)C(c1ccccc1)c1nn[nH]n1,,Cc1ccccc1,,CCCC[Sn](=O)CCCC,,test
US20050176775A1,CC(=O)OCc1cc(OCc2ccc(F)cc2F)c(Cl)c(=O)n1-c1cccc(C(N)=O)c1>>NC(=O)c1cccc(-n2c(CO)cc(OCc3ccc(F)cc3F)c(Cl)c2=O)c1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20040009993A1,C1CCOC1.CSc1nc(C)c(C=O)c(Nc2ccc(C(=O)OC(C)(C)C)cc2)n1>>CCOC(=O)/C=C/c1c(C)nc(SC)nc1Nc1ccc(C(=O)OC(C)(C)C)cc1,,C1CCOC1,,,,test
US20130123252A1,C1CCNC1.O=C(O)c1sc(-c2ccccc2)cc1N1C(=O)CN(S(=O)(=O)c2ccc(Cl)nc2)C[C@H]1C1CCCCC1>>O=C(O)c1sc(-c2ccccc2)cc1N1C(=O)CN(S(=O)(=O)c2ccc(N3CCCC3)nc2)C[C@H]1C1CCCCC1,,CN(C)C=O,,CCN(CC)CC,,test
US20110147681A1,COC(=O)c1c2c(c3ccccc3c1O)OC(c1ccc(OC)cc1)(c1ccc(OC)cc1)C=C2>>C1=Cc2c(ccc3ccccc23)OC1,,C1CCOC1,,CCN(CC)CC,,test
US20140155385A1,Nc1nc2c(s1)CCCC2.O=C(Cl)c1ccc(Br)cc1>>O=C(Nc1nc2c(s1)CCCC2)c1ccc(Br)cc1,,O,c1ccncc1,,,test
US20100099690A1,CCCCCn1c(=O)n(-c2ccccc2)c(=O)c2c1ncn2Cc1ccc(OC)cc1>>CCCCCn1c(=O)n(-c2ccccc2)c(=O)c2[nH]cnc21,[Pd],CC(=O)O,CCO,,,test
US20130158082A1,CNC(N)=S.O=C1C(Cl)=C(Cl)C(=O)c2ccccc21>>CNc1nc2c(s1)C(=O)c1ccccc1C2=O,,CC(C)O,,O=C([O-])[O-].[K+].[K+],,test
US20120208852A1,Cc1noc(C(NC(=O)OC(C)(C)C)c2cccc(C(F)(F)F)c2)n1.Cl>>Cc1noc(C(N)c2cccc(C(F)(F)F)c2)n1.Cl,,C1COCCO1,ClCCl,,,test
US20160244449A1,CCN1C(=O)N(c2c(F)c(OC)cc(OC)c2F)Cc2cnc(-c3c[nH]nc3C)cc21.O=C(CCl)N1CCOCC1>>CCN1C(=O)N(c2c(F)c(OC)cc(OC)c2F)Cc2cnc(-c3cn(CC(=O)N4CCOCC4)nc3C)cc21,,CC#N,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100240658A1,COC(=O)c1ccc(C#N)c(OC)c1.NO>>COC(=O)c1ccc(C(N)=NO)c(OC)c1,,CCO,,,,test
US04377695,COC(=O)CCCCCCCn1c(=O)[nH]c2ccccc21.ClCc1ccc(Cl)cc1>>COC(=O)CCCCCCCn1c(=O)n(Cc2ccc(Cl)cc2)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20130336920A1,FC(F)(F)c1cccc([Mg]Cl)c1.O=Cc1ccnc(-c2cc(N3CCCCC3)ccc2[N+](=O)[O-])c1>>O=[N+]([O-])c1ccc(N2CCCCC2)cc1-c1cc(C(O)c2cccc(C(F)(F)F)c2)ccn1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20070027187A1,CC(C)(C)OC(=O)NCCOS(C)(=O)=O.Oc1ccc(F)cc1>>CC(C)(C)OC(=O)NCCOc1ccc(F)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US05468743,COc1cccc(CCCl)c1.c1c[nH]cn1>>COc1cccc(CCn2ccnc2)c1,,CC(=O)CC(C)C,O,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US20130196993A1,CCOC(=O)CC(=O)C(F)(F)C(F)F>>CCOC(=O)CC(O)C(F)(F)C(F)F,,Cc1ccccc1,,Cl,[BH4-].[Na+],test
US04238498,O=S(Cl)Cl.OC(c1ccccc1)c1ccc(C2CCCCC2)cc1>>ClC(c1ccccc1)c1ccc(C2CCCCC2)cc1,,c1ccccc1,,,,test
US20090324569A1,COc1ccc(CN2C[C@@H](O[Si](C)(C)C(C)(C)C)CC2=O)cc1-c1cccc([N+](=O)[O-])c1>>CC(C)(C)[Si](C)(C)O[C@@H]1CNC(=O)C1,,O,,C1CCOC1,[H-].[Na+],test
US20140148459A1,COC(=O)C(CCn1nnc2ccc(C)cc2c1=O)Sc1ccc(N)cc1.COc1ccc(C(=O)Cl)cc1>>COC(=O)C(CCn1nnc2ccc(C)cc2c1=O)Sc1ccc(NC(=O)c2ccc(C)cc2)cc1,,ClCCl,,O,c1ccncc1,test
US20060199960A1,CCOC(=O)c1nc(C)ccc1Br.Cn1nc(C2CC2)cc1N>>CCOC(=O)c1nc(C)ccc1Nc1cc(C2CC2)nn1C,[Pd],,,,,test
US20010001101A1,COCCOCCO.O=C1c2ccc3cccnc3c2N=CC1C(=O)n1ccnc1>>COCCOCCOC(=O)C1C=Nc2c(ccc3cccnc23)C1=O,,CC(=O)O,,CN(C)C=O,[H-].[Na+],test
US20110212945A1,Cc1ccc(Nc2cnc(-c3ccccc3)c(F)c2)c(C(=O)OC(C)(C)C)c1>>Cc1ccc(Nc2cnc(-c3ccccc3)c(F)c2)c(C(=O)O)c1,,O=C(O)C(F)(F)F,,,,test
US20100029650A1,CC(C)c1noc(N2CCC(CO)CC2)n1.CS(=O)(=O)c1ccc(-c2ncc(O)cn2)cc1>>CC(C)c1noc(N2CCC(COc3cnc(-c4ccc(S(C)(=O)=O)cc4)nc3)CC2)n1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090005353A1,CC(C)(C)OC(=O)NCCc1ccc(O)cc1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NCCc1ccc(OS(C)(=O)=O)cc1,,ClCCl,,,,test
US20140371278A1,COC(=O)c1cc2scnc2c(F)c1Nc1ccccc1F.O=C1CCC(=O)N1I>>COC(=O)c1cc2scnc2c(F)c1Nc1ccc(I)cc1F,,CN(C)C=O,,O,O=C(O)C(F)(F)F,test
US20150232461A1,COc1ccc(Cn2cc(C=NO)c(Cc3ccccc3F)n2)cc1.O=C1CCC(=O)N1Cl>>COc1ccc(Cn2cc(C(Cl)=NO)c(Cc3ccccc3F)n2)cc1,,CCOC(C)=O,CN(C)C=O,,,test
US20160122341A1,Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(-c3cnn(CCO)c3)n2c1.O=C=NS(=O)(=O)Cl>>Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(-c3cnn(CCOC(N)=O)c3)n2c1,,ClCCl,,,,test
US20110306599A1,CN(C(=O)CN1CCCCC1=O)c1ccc2cc(-c3nn(COCC[Si](C)(C)C)c4c3CCC(C)(CO)C4)n(COCC[Si](C)(C)C)c2c1>>CN(C(=O)CN1CCCCC1=O)c1ccc2cc(-c3n[nH]c4c3CCC(C)(CO)C4)[nH]c2c1,,CN(C)C=O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080108648A1,O=S(Cl)Cl.OCc1cc(OCc2ccccc2)ccn1>>ClCc1cc(OCc2ccccc2)ccn1,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20070004772A1,CC(C)CCBr.O=c1[nH]nc2c(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)ccn12>>CC(C)CCn1nc2c(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)ccn2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040077669A1,C#CCO.Fc1cccc(-c2cc(Cl)ncn2)c1F>>C#CCOc1cc(-c2cccc(F)c2F)ncn1,,CN(C)C=O,,O,[H-].[Na+],test
US20030055120A1,CC(C)(O)C(=O)c1ccc(OCCO)cc1.O=C(OC(=O)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)F>>CC(C)(O)C(=O)c1ccc(OCCOC(=O)C(F)(F)C(F)(F)C(F)(F)F)cc1,,C1CCOC1,,O,,test
US20060211698A1,CN(C)/C=C/c1cc(Br)ccc1[N+](=O)[O-].O>>O=Cc1cc(Br)ccc1[N+](=O)[O-],,O,,C1CCOC1,,test
US20130217722A1,CCc1cc(C2=CCN(C(=O)OC(C)(C)C)CC2)ccc1N(C)c1cc2c(cn1)ncn2C>>CCc1cc(C2=CCNCC2)ccc1N(C)c1cc2c(cn1)ncn2C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140288123A1,Cc1cc(C(C)c2ccccc2)ccc1C(=O)OC(C)(C)C>>Cc1cc(C(C)c2ccccc2)ccc1C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090221586A1,CC(C)Br.CCOc1ccccc1C(=O)CCc1coc(-c2ccc(OC(F)F)c(O)c2)n1>>CCOc1ccccc1C(=O)CCc1coc(-c2ccc(OC(F)F)c(OC(C)C)c2)n1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20110152245A1,CC(C)(C)OC(=O)N1CCCO[C@@H](c2ccc(NC(=O)c3cccc(Cl)c3)cc2)C1.Cl>>Cl.O=C(Nc1ccc([C@H]2CNCCCO2)cc1)c1cccc(Cl)c1,,C1COCCO1,,,,test
US20060142317A1,C1CNCCN1.Cc1ccc2onc(Cl)c2c1>>Cc1ccc2onc(N3CCNCC3)c2c1,,O,,C1CCC2=NCCCN2CC1,,test
US20120077799A1,Cc1cnc(N)c(-c2ccc(OC3CCCCC3)nc2)n1.O=S(=O)(Cl)CCCl>>CC1=CN2CCS(=O)(=O)N=C2C(c2ccc(OC3CCCCC3)nc2)=N1,,C1CCOC1,,[H-].[Na+],,test
US20100256097A1,Cc1nc(Cl)ccc1C=O>>Cc1nc(Cl)ccc1CO,,CO,,[BH4-].[Na+],,test
US03936468,C1CCNCC1.O=C(O)CCC(=O)c1ccc(F)cc1>>O=C(CCC(=O)N1CCCCC1)c1ccc(F)cc1,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US20160052920A1,C[C@](N)(C[C@H](O)C(F)(F)F)c1nc(Br)ccc1F.N#CBr>>C[C@@]1(c2nc(Br)ccc2F)C[C@@H](C(F)(F)F)OC(N)=N1,,CC#N,CCO,,,test
US05011774,Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O.O>>OC[C@@H]1CC[C@H](n2cnc3c(O)ncnc32)O1,,CO,,,,test
US20140296183A1,CCCCCCCOc1ccc(Br)cc1C=O>>CCCCCCCOc1ccc(Br)cc1CO,,CCO,,Cl,[BH4-].[Na+],test
US04711899,CC(Br)C(=O)c1ccc(F)cc1.Fc1ccc(C2(C3CCNCC3)OCCO2)cc1>>CC(C(=O)c1ccc(F)cc1)N1CCC(C2(c3ccc(F)cc3)OCCO2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090312381A1,CNC(=O)NNC(=O)c1ccc(Cl)cc1>>Cn1c(-c2ccc(Cl)cc2)n[nH]c1=O,,[Na+],[OH-],O=C(O)CC(O)(CC(=O)O)C(=O)O,,test
US09303020B2,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.O=[N+]([O-])c1cc2oc(-c3ccc(F)cc3)c(-c3ncc[nH]3)c2cc1O>>O=[N+]([O-])c1cc2oc(-c3ccc(F)cc3)c(-c3nccn3S(=O)(=O)C(F)(F)F)c2cc1OS(=O)(=O)C(F)(F)F,,O,c1ccncc1,,,test
US20100311990A1,C#CC1(O)C(C)CC=C2C(C)(C)CCCC21C>>CC1=C(CC=O)C2(C)CCCC(C)(C)C2=CC1,,Cc1ccccc1C,,[Na+].[OH-],,test
US20070161654A1,CON(C)C(=O)c1c(-c2ccccc2)noc1C1CC1.C[Mg]Br>>CC(=O)c1c(-c2ccccc2)noc1C1CC1,,C1CCOC1,,,,test
US04604406,COC(=O)c1cccc2c(C(F)(F)C(F)(F)F)c(OC)ccc12>>COc1ccc2c(C(=O)O)cccc2c1C(F)(F)C(F)(F)F,,CO,,Cl,[Na+].[OH-],test
US20130324506A1,CC(C)N=C=S.Cc1c(-c2ccc(N)cc2)nc2n1CCc1ccccc1C2OC1CCN(C)CC1>>Cc1c(-c2ccc(NC(=S)NC(C)C)cc2)nc2n1CCc1ccccc1C2OC1CCN(C)CC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20060047123A1,NCCCCCC(=O)Nc1ccccc1.O=C(Br)CBr>>O=C(CBr)NCCCCCC(=O)Nc1ccccc1,,C1CCOC1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US20090247567A1,CNc1ccccc1F.Cc1ccc2c(c1)-c1sc(C(=O)O)cc1CO2>>Cc1ccc2c(c1)-c1sc(C(=O)N(C)c3ccccc3F)cc1CO2,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20080161366A1,O=S1(=O)Nc2ccccc2N1c1ccc(Cl)cc1.OCCCBr>>O=S1(=O)N(CCCBr)c2ccccc2N1c1ccc(Cl)cc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110301109A1,CCCOc1ccc([N+](=O)[O-])cc1-c1nc(CC)c(CC)c(=O)[nH]1>>CCCOc1ccc(N)cc1-c1nc(CC)c(CC)c(=O)[nH]1,[Pd],CO,,,,test
US20020016472A1,O=C(CCl)c1ccc(O)cc1O.Oc1cccc(O)c1>>ClCC1c2ccccc2Oc2ccccc21,,CS(=O)(=O)O,,,,test
US20120202794A1,CCOC(=O)/C(=N/O)NC(=O)c1ccc(F)cc1>>CCOC(=O)c1noc(-c2ccc(F)cc2)n1,,CN(C)C=O,,,,test
US20090036492A1,COC(=O)/C=C/c1cc(C=O)c2ccccc2c1.COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>COC(=O)/C=C/c1cc(CNC(=O)c2c(OC)cc(O)c3c2OC2=CC(O)=C(C(C)=O)C(=O)[C@]23C)c2ccccc2c1,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20160272617A1,Cc1cc(C(=O)O)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc3c(Cl)n[nH]c3c2)cc1.N[C@H]1CCCNC1=O>>Cc1cc(C(=O)N[C@H]2CCCNC2=O)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc3c(Cl)n[nH]c3c2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05856492,CC(C(O)c1ccccc1)N1CCCC1.Cl>>CC(C(O)c1ccccc1)N1CCCC1.Cl,,CC(C)O,,Cc1ccccc1,,test
US20100331326A1,Cc1ccncc1N1CCNC1=O.Fc1ccc(Br)cc1Cl>>Cc1ccncc1N1CCN(c2ccc(F)c(Cl)c2)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=C([O-])[O-].[K+].[K+],test
US20050143429A1,CC(C)OC(OC(C)C)C(C)(C)C(=O)C(C)C(O)C(C)COCc1ccccc1.O=C(Cl)OCC(Cl)(Cl)Cl>>CC(C)OC(OC(C)C)C(C)(C)C(=O)C(C)C(OC(=O)OCC(Cl)(Cl)Cl)C(C)COCc1ccccc1,,ClCCl,,c1ccncc1,,test
US20100130446A1,C[C@H]1CNCCN1.O=Cc1ccc(-c2ccc(C(CC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)[nH]2)nc1>>C[C@H]1CN(Cc2ccc(-c3ccc(C(CC4CCOCC4)c4ccc(S(=O)(=O)C5CC5)cc4)[nH]3)nc2)CCN1,,C1CCOC1,CCOC(C)=O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100056576A1,C[C@@H](CO)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1COC(C)(C)O1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>C[C@@H](CN=[N+]=[N-])[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1COC(C)(C)O1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140179668A1,COC(=O)C1[C@@H](O)CCN1c1nc2c(c(Nc3cc(C4CC4)[nH]n3)n1)CCC2.Nc1ccc(F)nc1>>O=C(Nc1ccc(F)nc1)[C@H]1[C@@H](O)CCN1c1nc2c(c(Nc3cc(C4CC4)[nH]n3)n1)CCC2,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20150329538A1,CC1(N)CC1.Cc1nc2ccc(F)c(Br)c2[nH]c1=O>>Cc1nc2ccc(F)c(Br)c2nc1NC1(C)CC1,,CS(C)=O,,CCN(C(C)C)C(C)C,Cl,test
US04789680,CC#CC(=O)O.[N-]=[N+]=NCc1c(F)cccc1Cl>>O=C(O)c1cn(Cc2c(F)cccc2Cl)nn1,,Cc1ccccc1,,,,test
US20150183824A1,CCCC(NC(=O)OC(C)(C)C)C(OC)(OC)C(=O)NC1CC1>>CCCC(N)C(OC)(OC)C(=O)NC1CC1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US06239159B1,COC(=O)CCCCBr.O=[N+]([O-])c1ccc2[nH]ccc2c1>>COC(=O)CCCCn1ccc2cc([N+](=O)[O-])ccc21,,CC#N,,[H-].[Na+],,test
US20150353499A1,COc1ccc2c(F)cccc2c1C=O>>COc1ccc2c(F)cccc2c1CO,,CCO,Cl,[BH4-].[Na+],,test
US20020137766A1,CN(C(=O)OC(C)(C)C)C1C2CCC1CNC2.COc1ccc(OC(CCCOS(C)(=O)=O)c2ccc(C#N)cc2)cc1OC>>COc1ccc(OC(CCCN2CC3CCC(C2)C3N(C)C(=O)OC(C)(C)C)c2ccc(C#N)cc2)cc1OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050137203A1,CS(=O)(=O)Nc1ccc(-c2ccc(OC3CN4CCC3CC4)cc2)cc1.O=C(O)/C=C/C(=O)O>>CS(=O)(=O)Nc1ccc(-c2ccc(OC3CN4CCC3CC4)cc2)cc1.O=C(O)/C=C/C(=O)O,,CCO,CCOC(C)=O,,,test
US20100216763A1,CCOC(=O)CC(=O)CCl.Nc1cccc(C(=O)NCC23CC4CC(CC(C4)C2)C3)n1>>CCOC(=O)Cc1cn2c(C(=O)NCC34CC5CC(CC(C5)C3)C4)cccc2n1,,CCO,,,,test
US05386023,Cc1cn([C@H]2C[C@H](O)[C@@H](CO[Si](C)(C)C(C)(C)C)O2)c(=O)[nH]c1=O.O=C1c2ccccc2C(=O)N1O>>Cc1cn([C@H]2C[C@H](ON3C(=O)c4ccccc4C3=O)[C@@H](CO[Si](C)(C)C(C)(C)C)O2)c(=O)[nH]c1=O,,C1CCOC1,CCOCC,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05786358,C#Cc1cnc2nc(NC(=O)C(C)(C)C)nc(O)c2c1.CCOC(=O)CNS(=O)(=O)c1ccc(Br)s1>>CCOC(=O)CNS(=O)(=O)c1ccc(C#Cc2cnc3nc(NC(=O)C(C)(C)C)nc(O)c3c2)s1,Cl[Pd]Cl,CC#N,,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050075331A1,CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(NS(=O)(=O)N4CCOC4=O)ccc3N2)c(O)c2cccnc21.OC1CNC1>>CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(NS(=O)(=O)N4CC(O)C4)ccc3N2)c(O)c2cccnc21,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US20090143420A1,Cc1ccc2nc(C(=O)c3ccccc3)cn2c1.Cl>>Cc1ccc2nc(C(=O)c3ccccc3)cn2c1.Cl,,C1COCCO1,CCO,CCOCC,,test
US20030013708A1,CNC.COc1cc(Br)c2nc(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(Cl)c2c1>>COc1cc(Br)c2nc(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(N(C)C)c2c1,,C1CCOC1,,,,test
US20020156087A1,C1COCCN1.CCOC(=O)c1ccc(Cl)nc1>>CCOC(=O)c1ccc(N2CCOCC2)nc1,,O,,CC#N,,test
US20120232056A1,CNCc1ccccc1.COC(=O)c1ccc2[nH]c(=O)c(Cl)nc2c1>>COC(=O)c1ccc2[nH]c(=O)c(N(C)Cc3ccccc3)nc2c1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20010039280A1,CN1CCN(c2ccccc2CC2CCN(c3ccc(C(F)(F)F)cc3)C2=O)CC1.Cc1ccc(C(=O)[C@@](O)(C(=O)O)[C@](O)(C(=O)O)C(=O)c2ccc(C)cc2)cc1>>CN1CCN(c2ccccc2C[C@H]2CCN(c3ccc(C(F)(F)F)cc3)C2=O)CC1.Cc1ccc(C(=O)[C@@](O)(C(=O)O)[C@](O)(C(=O)O)C(=O)c2ccc(C)cc2)cc1,,CCC(C)=O,,,,test
US20080207685A1,COC(=O)C=Cc1ccc(O)c2c1CN(C(=O)OC(C)(C)C)C2>>COC(=O)CCc1ccc(O)c2c1CN(C(=O)OC(C)(C)C)C2,[Pd],CO,,C1CCOC1,,test
US20120232057A1,CC(C)[C@H]1COCc2nc3cnc4ccccc4c3n21.O=C(OO)c1cccc(Cl)c1>>CC(C)[C@H]1COCc2nc3c[n+]([O-])c4ccccc4c3n21,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20040067960A1,CC1(C)CCNc2c(CCN3CCN(c4nsc5ccccc45)CC3)cccc21.Cc1nc(S(=O)(=O)Cl)cn1C>>Cc1nc(S(=O)(=O)N2CCC(C)(C)c3cccc(CCN4CCN(c5nsc6ccccc56)CC4)c32)cn1C,,c1ccncc1,,,,test
US20110201605A1,CC(C)(C)OC(=O)N1CCC(N=C=S)CC1.NN1CC(O)CC(c2ccc(F)cc2Cl)C1=O>>CC(C)(C)OC(=O)N1CCC(NC(=S)NN2CC(O)CC(c3ccc(F)cc3Cl)C2=O)CC1,,CC(=O)N(C)C,CCOC(C)=O,,,test
US20100286189A1,CCn1c(-c2ccc(C)cc2)cc2cc([N+](=O)[O-])cnc21>>CCn1c(-c2ccc(C)cc2)cc2cc(N)cnc21,,CCO,CCOC(C)=O,,,test
US20080318945A1,CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCN(C(=O)CN)CC1.O=S(=O)(Cl)c1ccc(Cl)cc1Cl>>CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCN(C(=O)CNS(=O)(=O)c2ccc(Cl)cc2Cl)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US04910202,CN(CCN)CCN.Nc1nc(N)c(C(=O)n2ccnc2)nc1Br>>CN(CCN)CCNC(=O)c1nc(Br)c(N)nc1N,,C1CCOC1,,,,test
US04209616,CC(=O)OCC1=C(C(=O)OC(C)(C)C)N2C(=O)[C@@H](NC(=O)C(=NOC(=O)C(Cl)Cl)c3cccs3)[C@H]2SC1>>CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)C(=NOC(=O)C(Cl)Cl)c3cccs3)[C@H]2SC1,,COc1ccccc1,,O=C(O)C(F)(F)F,,test
US20050261294A1,CC(C)c1ccc(-c2csc(NCc3cccs3)n2)cc1.O=C(O)c1ccc(S(=O)(=O)Cl)cc1>>CC(C)c1ccc(-c2csc(N(Cc3cccs3)S(=O)(=O)c3ccc(C(=O)O)cc3)n2)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US06297266B1,COC(=O)CBr.O=[N+]([O-])c1ccc(Nc2ccccc2)cc1>>COC(=O)CN(c1ccccc1)c1ccc([N+](=O)[O-])cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05556886,CCc1ccc(C#N)c([N+](=O)[O-])c1.OO>>CCc1ccc(C(N)=O)c([N+](=O)[O-])c1,,O,,CCO,[Na+].[OH-],test
US20110201592A1,CC(C)(C)OC(=O)N1CC[C@H](Nc2cc(-c3ccccc3O)nc3ccccc23)C1>>Oc1ccccc1-c1cc(N[C@H]2CCNC2)c2ccccc2n1,,C1COCCO1,CO,Cl,,test
US20090318447A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(CC1CCOCC1)N(CC1CCN(Cc2ccc(C(F)(F)F)cc2)CC1)c1ccc(N2CCOCC2)nc1>>CC(C)(C)OC(=O)N1CCC(CN(C(=O)CC2CCOCC2)c2ccc(N3CCOCC3)nc2)CC1,[Pd],CCO,,,,test
US20090221555A1,Clc1ncc(Cl)c(Cl)n1.N#CCCc1cccc(N)c1>>N#CCCc1cccc(Nc2nc(Cl)ncc2Cl)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100305096A1,CN(C1CCOCC1)C1CCN(C(=O)OC(C)(C)C)CC1>>CN(C1CCNCC1)C1CCOCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06545183B1,C1CCOC1.CCOCC.Pc1ccccc1.[Li]CCCC>>CC[C@@H]1C[C@@H](CC)P1c1ccccc1,,CCOCC,,,,test
US04578378,CCOC(=O)C1SCCCC1=O.CO.COC([O-])[O-]>>CCOC(=O)C1SCCCC1(OC)OC,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20030148997A1,CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](F)[C@@H]1O.CC(=O)OC(C)=O.c1ccncc1>>CC(=O)N[C@H]1C(OC(C)=O)O[C@H](COC(C)=O)[C@@H](F)[C@@H]1OC(C)=O,,c1ccncc1,,,,test
US06498254B1,CC(=O)OO.Cc1ccc([N+](=O)[O-])c(CS(=O)c2cccc[n+]2[O-])c1>>Cc1ccc([N+](=O)[O-])c(CS(=O)(=O)c2cccc[n+]2[O-])c1,,CC(=O)O,,,,test
US04158734,CC(=O)O.CCCC1C(CC)=CC(CC)=CN1C>>CC(=O)[O-].CCCc1c(CC)cc(CC)c[n+]1C,,O,,,,test
US05254595,NC1CCCc2ccccc21.O[C@@H]1Cc2cccc(OCC3CO3)c2C[C@H]1O>>OC(CNC1CCCc2ccccc21)COc1cccc2c1C[C@@H](O)[C@H](O)C2,,CCO,,,,test
US20160137639A1,CC(C)Cc1cc(-c2onc([C@@H](CCCOCc3ccccc3)CC(=O)OC(C)(C)C)c2C2CC2)on1>>CC(C)Cc1cc(-c2onc([C@@H](CCCOCc3ccccc3)CC(=O)O)c2C2CC2)on1,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US20070281936A1,CI.Nc1nc(C(=O)NCc2ncc[nH]2)cc(-c2ccco2)n1>>Cn1ccnc1CNC(=O)c1cc(-c2ccco2)nc(N)n1,,CN(C)C=O,,O,[H-].[Na+],test
US20070004710A1,COc1ccc2nccc(-c3ccc(CCNC(=O)OC(C)(C)C)nc3)c2n1.Cl>>COc1ccc2nccc(-c3ccc(CCN)nc3)c2n1.Cl,,C1CCOC1,C1COCCO1,,,test
US05550130,Fc1ccc2c(C3CCNCC3)noc2c1.NC(=O)CBr>>NC(=O)CN1CCC(c2noc3cc(F)ccc23)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120094996A1,COc1cc(-c2nn3c(-c4cnc(N)c(C(F)(F)F)c4)cnc3s2)ccc1OC1CCN(C(=O)OC(C)(C)C)CC1.Cl>>COc1cc(-c2nn3c(-c4cnc(N)c(C(F)(F)F)c4)cnc3s2)ccc1OC1CCNCC1.Cl,,ClCCl,,C1COCCO1,,test
US05773463,O=C1N[C@@H]2Cc3ccccc3[C@@H]2O1>>N[C@H]1Cc2ccccc2[C@H]1O,,CCO,O,[Na+].[OH-],,test
US20140315879A1,CC(C)(C)OC(=O)c1cc(Cl)c(CBr)cc1F.Oc1cnc(C2CC2)c(Cl)c1>>CC(C)(C)OC(=O)c1cc(Cl)c(COc2cnc(C3CC3)c(Cl)c2)cc1F,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150072969A1,CCOC(=O)CC1(c2ccc(OCc3cccc(Br)c3)cc2)COC1.OB(O)c1ccc(O)cc1Cl>>CCOC(=O)CC1(c2ccc(OCc3cccc(-c4ccc(O)cc4Cl)c3)cc2)COC1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US05344964,C1CCOC1.CC(=O)O>>CC(=O)[O-].CCOCC,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20140135316A1,CCOC(=O)CCNc1cccc(F)c1[N+](=O)[O-]>>CCOC(=O)CCNc1cccc(F)c1N,[Pd],CCOC(C)=O,,CCO,,test
US20020193398A1,CCOC(=O)Cc1c(F)c(F)nc(F)c1Cl.NCC(F)(F)c1ccccn1>>CCOC(=O)Cc1c(F)c(NCC(F)(F)c2ccccn2)nc(F)c1Cl,,CN(C)C=O,,O=C([O-])[O-].[Ca+2],,test
US20120046472A1,O=[N+]([O-])c1ccc(Oc2cccc(-c3nnc(-c4cc(O)c(-c5nnc(-c6cccc(Oc7ccc([N+](=O)[O-])cc7)c6)o5)cc4O)o3)c2)cc1>>Nc1ccc(Oc2cccc(-c3nnc(-c4cc(O)c(-c5nnc(-c6cccc(Oc7ccc(N)cc7)c6)o5)cc4O)o3)c2)cc1,[Pd],C1CCOC1,,,,test
US05646308,CNC(=O)C1=CC(CF)(CF)Oc2ccc([N+](=O)[O-])cc21.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CNC(=S)C1=CC(CF)(CF)Oc2ccc([N+](=O)[O-])cc21,,c1ccccc1,,,,test
US20030199440A1,CC(C)(C)OC(=O)CNCc1ccccc1.O=S(=O)(Cl)c1ccc2c(Cl)cnc(Cl)c2c1>>CC(C)(C)OC(=O)CN(Cc1ccccc1)S(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1,,ClCCl,,CCN(CC)CC,,test
US20110230476A1,CCOP(=O)(CC(=O)CCC(=O)N1CCN(Cc2cc3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3s2)CC1)OCC.O=CC1CC1>>O=C(/C=C/C1CC1)CCC(=O)N1CCN(Cc2cc3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3s2)CC1,,C1CCOC1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20020198197A1,COCCOc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1-n1cccc1>>COCCOc1cc(NC(=O)OC(C)(C)C)c(N)cc1-n1cccc1,[Ni],,,,,test
US05864039,O=C(CCBr)c1ccccc1.OCCO>>BrCCC1(c2ccccc2)OCCO1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080269196A1,C[C@@H](N)C(F)(F)F.O=C(N=C=S)c1ccccc1>>C[C@@H](NC(=S)NC(=O)c1ccccc1)C(F)(F)F,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20060211698A1,Cc1nc(C)c(C(=O)O)s1.Nc1ccc(Br)cc1N>>Cc1nc(C)c(-c2nc3ccc(Br)cc3[nH]2)s1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070179167A1,CC(C)I.Cc1cc(C=O)cc(C)c1O>>Cc1cc(C=O)cc(C)c1OC(C)C,,C1CCOC1,COC(C)(C)C,[K+].[OH-],,test
US20070155746A1,CCOC(OCC)c1cc(O)ncn1>>O=Cc1cc(O)ncn1,,Cl,,,,test
US20110195954A1,COc1ccc2c(c1)CCN(C1CCNCC1)C(=O)N2.O=C(O)c1cc(Br)ccn1>>COc1ccc2c(c1)CCN(C1CCN(c3ccnc(C(=O)O)c3)CC1)C(=O)N2,,CN1CCCC1=O,,O=CO,,test
US20070142413A1,CSc1nc(O)c2c(n1)CN(C(=O)OCc1ccccc1)CC2.O=P(Cl)(Cl)Cl>>CSc1nc(Cl)c2c(n1)CN(C(=O)OCc1ccccc1)CC2,,ClC(Cl)Cl,,,,test
US20060154960A1,CCC(Br)CC.CCc1n[nH]c2cc(-c3ccnn3-c3ccc(S(C)(=O)=O)cc3)ccc12>>CCc1c2ccc(-c3ccnn3-c3ccc(S(C)(=O)=O)cc3)cc2nn1C(CC)CC,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04145524,N#Cc1ccc(C#N)cc1.NO.NO>>NC(=O)c1ccc(C(N)=NO)cc1,,CCO,,Cl,[Na],test
US20120142717A1,CI.O=c1nc(OCCc2ccc(Oc3ccc(Cl)c(C(F)(F)F)c3)cc2)[nH]cc1Cc1cncnc1>>Cn1cc(Cc2cncnc2)c(=O)nc1OCCc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070232583A1,Cc1cc(-c2ccc(C(F)(F)F)cc2)nc(-n2cnc(-c3ccc(S(=O)(=O)NC(C)(C)C)cc3)c2)n1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)nc(-n2cnc(-c3ccc(S(N)(=O)=O)cc3)c2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100305122A1,CC(C)(C)OC(=O)N(CCCNc1ccc(S(N)(=O)=O)cc1[N+](=O)[O-])C1CC1>>NS(=O)(=O)c1ccc(NCCCNC2CC2)c([N+](=O)[O-])c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04670447,CC(=O)N1CCC(C(=NN)c2ccc(Cl)cc2F)CC1>>CC(=O)N1CCC(c2n[nH]c3cc(Cl)ccc23)CC1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140066369A1,CCOC(=O)C1CCC(=O)CC1.C[C@H]1CN(C(=O)OC(C)(C)C)CCN1>>CCOC(=O)C1CCC(N2CCN(C(=O)OC(C)(C)C)C[C@@H]2C)CC1,,ClCCl,O,CC(=O)O,[Na+].[OH-],test
US20140275043A1,CCOC(=O)c1cccc(O)c1.ClCc1ccccc1>>CCOC(=O)c1cccc(OCc2ccccc2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06479531B1,CCOC(=O)C(N)C(=O)CCC12CC3CC(CC(C3)C1)C2.Cc1ccccc1C(=O)Cl>>CCOC(=O)C(NC(=O)c1ccccc1C)C(=O)CCC12CC3CC(CC(C3)C1)C2,,C1CCOC1,CN(C)C=O,Cl,,test
US06566535B1,COC(=O)CCCS.O=Cc1ccccc1F>>COC(=O)CCCSc1ccccc1C=O,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20140371271A1,CCOP(=O)(OCC)OC/C=C/C(=O)N1CCCCC1.COc1ccc(OC)c(C=O)c1>>COc1ccc(OC)c(/C=C/C=C/C(=O)N2CCCCC2)c1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20150197511A1,CC(C)(C)OC(=O)Nc1ccc(O)cc1F.Fc1ccnc(Cl)c1>>CC(C)(C)OC(=O)Nc1ccc(Oc2ccnc(Cl)c2)cc1F,,CN1CCCC1=O,,CC(C)(C)[O-].[K+],,test
US06376491B1,CCOC(=O)c1oc2cccc(OCCCBr)c2c1C1CC1.NCc1cccnc1>>CCOC(=O)c1oc2cccc(OCCCNCc3cccnc3)c2c1C1CC1,,CCO,CCOC(C)=O,,,test
US20050203064A1,O=S(c1ccc(C=Cc2nc(CCl)co2)cc1)C(F)(F)F.OCCc1nccn1CCCCc1ccc(O)cc1>>O=S(c1ccc(/C=C/c2nc(COc3ccc(CCCCn4ccnc4CCO)cc3)co2)cc1)C(F)(F)F,,CN(C)C=O,,O,[H-].[Na+],test
US20040019063A1,CC(=O)Oc1ccc2cc([N+](=O)[O-])ccc2n1>>O=c1ccc2cc([N+](=O)[O-])ccc2[nH]1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20090186909A1,CC(=O)OCCOc1cc(C)c(-c2cccc(C=O)c2)c(C)c1.Nc1ccc(Cn2oc(=O)[nH]c2=O)cc1.[Na+]>>Cc1cc(OCCO)cc(C)c1-c1cccc(CNc2ccc(Cn3oc(=O)[n-]c3=O)cc2)c1.[Na+],,C1CCOC1,O,CC(=O)O,,test
US20090156642A1,O=C(CBr)c1ccccc1F.Sc1ccccc1>>O=C(CSc1ccccc1)c1ccccc1F,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20120142717A1,N#CN.O=S(=O)(O)C(F)(F)F.OCCc1cc(F)c(Oc2ccc(Cl)c(C(F)(F)F)c2)c(F)c1>>N=C(N)OCCc1cc(F)c(Oc2ccc(Cl)c(C(F)(F)F)c2)c(F)c1.O=S(=O)(O)C(F)(F)F,,C1CCOC1,,,,test
US20140121200A1,CC(C)(C)OC(=O)N1CC2CCNC2C1.O=C(OCC1c2ccccc2-c2ccccc21)ON1C(=O)CCC1=O>>CC(C)(C)OC(=O)N1CC2CCN(C(=O)OCC3c4ccccc4-c4ccccc43)C2C1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20070003539A1,CCN.N#Cc1ccccc1S(=O)(=O)Cl>>CCNS(=O)(=O)c1ccccc1C#N,,C1CCOC1,,,,test
US20160024016A1,CC1(C)CCC(=O)C[C@@H]1C=O.O=[Cr](=O)=O>>CC1(C)CCC(=O)C[C@@H]1C(=O)O,,CCOCC,,O=S(=O)(O)O,[Na+].[OH-],test
US20090156575A1,CC(C)(C)OC(=O)N1CCC2(CCNCC2)CC1.CC1(C)Cc2cccc(C=O)c2O1>>CC1(C)Cc2cccc(CN3CCC4(CCNCC4)CC3)c2O1,,CC#N,,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100261871A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCCCBr>>CC(C)(C)OC(=O)NCCCCBr,,ClCCl,,Br,CCN(CC)CC,test
US06344471B1,CCCC(=O)CCC(=O)OCC.CCCCCCI>>CCCCCCC(CC(=O)OCC)C(=O)CCC,,CCO,,[Na],,test
US20160016938A1,NN.O=C(c1cnc(Cl)cc1Cl)C1CC1>>Clc1cc2[nH]nc(C3CC3)c2cn1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,O,test
US20080242661A1,CN1N=CC2N=C(O)N=C(O)C21.O=C1CCC(=O)N1Br>>CN1N=C(Br)C2N=C(O)N=C(O)C21,,CC#N,,CC(=O)O,,test
US20150065522A1,O=S(Cl)Cl.OCc1cnn(-c2ccccn2)c1>>ClCc1cnn(-c2ccccn2)c1,,ClCCl,,,,test
US20120283247A1,CC(C)(C)OC(=O)N1CCCNCC1.O=S(=O)(Cl)c1ccccc1Cl>>CC(C)(C)OC(=O)N1CCCN(S(=O)(=O)c2ccccc2Cl)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160052940A1,[O-][NH2+]c1ncc(-c2cc(N3C[C@@H]4C[C@H]3CO4)nc(C3CC3(F)F)n2)cc1OC(F)F>>Nc1ncc(-c2cc(N3C[C@@H]4C[C@H]3CO4)nc(C3CC3(F)F)n2)cc1OC(F)F,,ClCCl,,ClP(Cl)Cl,,test
US20070082912A1,CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(C(F)(F)F)ccc2OCc2ccccc2)c1>>Cc1ccc(-c2cc(C(F)(F)F)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1,,CCOC(C)=O,,CCO,[Na+].[OH-],test
US04606860,C=CCN.CCOC=C1SC(=S)N(CC(=O)O)C1=O>>C=CCNC=C1SC(=S)N(CC(=O)O)C1=O,,CCO,,,,test
US20030064991A1,CC(=O)N(C)C1CCNC1.Cc1[nH]c2ccc(CCOS(C)(=O)=O)cc2c1C(=O)OCc1ccccc1>>Nc1cc2ccccc2[nH]1,,C1COCCO1,,,,test
US20140056928A1,C1CCNCC1.CCCCc1nc(NCc2ccc(OC)cc2OC)c2[nH]nc(CCCCCCCBr)c2n1>>CCCCc1nc(N)c2[nH]nc(CCCCCCCN3CCCCC3)c2n1,,CC#N,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20030212095A1,Brc1nccs1.N#Cc1ccc(OCC(O)CN2CC3CNCC(C3)C2)cc1>>N#Cc1ccc(OCC(O)CN2CC3CC(C2)CN(c2nccs2)C3)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100137299A1,COc1ccc(CN2C(=O)C(=O)c3ccccc32)cc1.N#Cc1ccc(O)cc1O>>COc1ccc(CN2C(=O)C(O)(c3cc(C#N)c(O)cc3O)c3ccccc32)cc1,,C1CCOC1,ClCCCl,CC(C)[Mg]Cl,Cl,test
US20070298104A1,Cc1cccc(C)c1Oc1ccc(C(=O)O)c(C(=O)O)c1.NCC(=O)O>>Cc1cccc(C)c1Oc1ccc2c(c1)C(=O)N(CC(=O)O)C2=O,,O,,,,test
US20130252936A1,II.OCCn1nc(-c2ccccc2)c2c(Cl)c(-c3ccccc3)nnc21>>Clc1c(-c2ccccc2)nnc2c1c(-c1ccccc1)nn2CCI,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100113512A1,CC(C)(C)C(=O)OCn1cnc(-c2cccc(-c3cc(F)c(C=O)c(F)c3)c2)n1.NC1Cc2ccccc2C1>>CC(C)(C)C(=O)OCn1cnc(-c2cccc(-c3cc(F)c(CNC4Cc5ccccc5C4)c(F)c3)c2)n1,,c1ccccc1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04165377,Br.Cl.N=C(N)Nc1nc(CCCCN2C(=O)c3ccccc3C2=O)cs1>>Br.Cl.N=C(N)Nc1nc(CCCCN)cs1,,O,,[K+].[OH-],,test
US20150291549A1,Cc1c(COc2ccc(C=O)c(O)c2)cccc1-c1ccc2c(c1)OCCO2.NC(=O)c1cccc(CCl)c1>>Cc1c(COc2ccc(C=O)c(OCc3cccc(C(N)=O)c3)c2)cccc1-c1ccc2c(c1)OCCO2,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20090181965A1,COc1cc(NC(N)=S)ccc1-n1cnc(C)c1.O=C1C(Br)CCCC1c1ccc(Cl)cc1>>COc1cc(Nc2nc3c(s2)CCCC3c2ccc(Cl)cc2)ccc1-n1cnc(C)c1,,CCO,,,,test
US06458772B1,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)OC(COC(=O)CCC(=O)O)COC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C.Nc1nc2c(ncn2[C@H]2C[C@H](F)[C@@H](CO)O2)c(=O)[nH]1>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)OC(COC(=O)CCC(=O)OC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)C[C@@H]1F)COC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C,CN(C)c1ccncc1,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20070219192A1,CC(C)(C)c1nc(-c2ccc(Br)cc2)c[nH]1.COS(=O)(=O)C(F)(F)F>>Cn1cc(-c2ccc(Br)cc2)nc1C(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20020193599A1,CC1(C)OC(=O)CC(=O)O1.[N-]=[N+]=NCCCC(=O)Cl>>CC1(C)OC(=O)C(C(=O)CCCN=[N+]=[N-])C(=O)O1,,ClCCl,,c1ccncc1,,test
US20110178063A1,COC(=O)c1ccn(C(C)C)n1.O=C1CCC(=O)N1Cl>>COC(=O)c1nn(C(C)C)cc1Cl,,CN(C)C=O,,,,test
US04036831,CC(=O)OCC(=O)C1=CC[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C>>CC(=O)OCC(=O)C1=CC[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O[Si](C)(C)C)C[C@]12C,,C1COCCO1,,,,test
US20040186102A1,C=O.CC(=O)c1cccc([N+](=O)[O-])c1.c1ccc(CC2CCNCC2)cc1>>O=C(CCN1CCC(Cc2ccccc2)CC1)c1cccc([N+](=O)[O-])c1,,CCO,CCOC(C)=O,Cl,,test
US20080108598A1,C=O.CC1(C)CC2CC(C)(CN2C(=O)c2ccc3[nH]ccc3c2)C1.CS(=O)(=O)[O-]>>CC1(C)CC2CC(C)(CN2C(=O)c2ccc3[nH]cc(CS(C)(=O)=O)c3c2)C1,,CN(C)C=O,,CC(=O)O,,test
US20060247320A1,CC(C)(C)C1CCc2nc3sc(C(=O)Cl)cc3cc2C1.COC(=O)[C@@H](N)Cc1ccc(O)cc1>>COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cc2cc3c(nc2s1)CCC(C(C)(C)C)C3,,CN(C)C=O,,Cl,O,test
US20010056123A1,ClI.O=C(O)c1cccc(O)c1>>O=C(O)c1ccc(I)c(O)c1,,CC(=O)O,,,,test
US04478834,CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ncccc1OCc1ccccc1>>CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ncccc1O,[Pd],CCO,,,,test
US20130065914A1,O=[N+]([O-])c1ccc(F)cc1OC(CF)CF>>Nc1ccc(F)cc1OC(CF)CF,[Ni],CO,,,,test
US20120157460A1,Cl.Cn1c2c(c3ccc(-n4ccc(-c5ccc(C(F)(F)F)nc5)cc4=O)nc31)CNCC2>>Cl.Cn1c2c(c3ccc(-n4ccc(-c5ccc(C(F)(F)F)nc5)cc4=O)nc31)CNCC2,,CCOCC,CO,,,test
US20160016935A1,COc1ccc(COc2ccnc(O[C@@H]3CC[C@@H](C)N(C(=O)OC(C)(C)C)C3)c2)cc1>>C[C@@H]1CC[C@@H](Oc2cc(O)ccn2)CN1C(=O)OC(C)(C)C,[Pd],CO,,,,test
US20060041123A1,CC(=O)OCc1cc2c(cn1)OCCC2>>OCc1cc2c(cn1)OCCC2,,C1CCOC1,O,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20160083401A1,O=P(Cl)(Cl)Cl.O=c1[nH]cnc2cc(N3CCOCC3)ncc12>>Clc1ncnc2cc(N3CCOCC3)ncc12,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20070072862A1,Cc1ccc(N)cc1C(=O)Nc1cnc(N)nc1.O=S(=O)(Cl)c1cccc(C(F)(F)F)c1>>Cc1ccc(NS(=O)(=O)c2cccc(C(F)(F)F)c2)cc1C(=O)Nc1cnc(N)nc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20020161237A1,CC(C)(C)OC(=O)n1nnc2cc(C=O)ccc21.COC(=O)C(NC(=O)c1ccc(C(=O)NCc2cccc(O)c2)cc1Br)P(=O)(OC)OC>>COC(=O)/C(=C/c1ccc2[nH]nnc2c1)NC(=O)c1ccc(C(=O)NCc2cccc(O)c2)cc1Br,,C1CCOC1,,CN(C)C(=N)N(C)C,,test
US04205080,ClC(Cl)Cl.O.Oc1ccc(-c2ccccc2)cc1>>O=Cc1cc(-c2ccccc2)ccc1O,,CCO,O,[Na+].[OH-],,test
US04452625,CC(C)(C)C1(C=Cc2ccc(Cl)cc2)CO1.c1nc[nH]n1>>CC(C)(C)C(O)(C=Cc1ccc(Cl)cc1)n1cncn1,,CCO,,,,test
US05846990,CNCc1cc(-c2ncco2)ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C.O=C(O)c1ccc(Cl)cc1Cl>>Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(-c3ncco3)cc2CN(C)C(=O)c2ccc(Cl)cc2Cl)c1C,,ClCCl,,CC(C)N=C=NC(C)C,,test
US20100004292A1,CC(C)(C)[Si](C)(C)OCCN(C#N)c1ccc(NC(=O)c2nscc2NC(=O)c2ccc(Cl)s2)cc1.CS(=O)(=O)O>>CS(=O)(=O)O.N=C1OCCN1c1ccc(NC(=O)c2nscc2NC(=O)c2ccc(Cl)s2)cc1,,CCOCC,,,,test
US05238599,CCCC[C@@H]1CC[C@@H](CCC(CO)CO)CC1.O=Cc1ccc(Br)c(F)c1>>CCCC[C@@H]1CC[C@@H](CCC2COC(c3ccc(Br)c(F)c3)OC2)CC1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20130029982A1,COc1ccc(Cn2c(C(C)Nc3ncnc4cccnc34)cc3nccc(C)c3c2=O)cc1>>Cc1ccnc2cc(C(C)Nc3ncnc4cccnc34)[nH]c(=O)c12,,O=C(O)C(F)(F)F,,,,test
US05631401,NC1CCCC1.O=Cc1ccc(Oc2ccccc2)cc1>>c1ccc(Oc2ccc(CNC3CCCC3)cc2)cc1,,CO,,[BH3-]C#N.[Na+],,test
US06034215,Cl.N[C@H]1CCCN(CC(=O)OCc2ccccc2)C1=O.O=CCc1ccccc1>>Cl.O=C(CN1CCC[C@H](NCCc2ccccc2)C1=O)OCc1ccccc1,,ClCCCl,,CCN(CC)CC,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20050197338A1,CCOc1cc(-n2cc(NC(N)=O)c(C(N)=O)n2)ccc1-c1ccc(O)cc1.NC(=O)CBr>>CCOc1cc(-n2cc(NC(N)=O)c(C(N)=O)n2)ccc1-c1ccc(OCC(N)=O)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100160369A1,C=CCc1cc(Cl)c(C#N)cc1Cl.NO>>C=CCc1cc(Cl)c(C(N)=NO)cc1Cl,,CCO,,CCN(CC)CC,Cl,test
US07001917B2,Cc1nn(-c2ccc(CCN)cc2)c(C)c1-c1ccccc1.O=C(Cl)Oc1ccccc1>>Cc1nn(-c2ccc(CCNC(=O)Oc3ccccc3)cc2)c(C)c1-c1ccccc1,,O,,CCN(CC)CC,ClCCl,test
US20160137653A1,Cc1ccc(N=C=O)cc1.NC1CCN(c2ccnc3ccc(F)cc23)CC1>>Cc1ccc(NC(=O)NC2CCN(c3ccnc4ccc(F)cc34)CC2)cc1,,C1CCOC1,CS(C)=O,CCN(C(C)C)C(C)C,Cl,test
US06235900B1,O=C(Cl)c1ccc(F)cc1F.c1cnc2c(c1)CNc1ccccc1N2>>O=C(c1ccc(F)cc1F)N1Cc2cccnc2Nc2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150266867A1,CC(C)(C)OC(=O)NCCNCCNC[C@H]1NC(=O)[C@H]1NC(=O)/C(=N\OC(C)(C)C(=O)OC(C)(C)C)c1csc(NC(=O)OC(C)(C)C)n1.O=C(n1ccnc1)n1ccnc1>>CC(C)(C)OC(=O)NCCN1CCN(C[C@H]2NC(=O)[C@H]2NC(=O)/C(=N\OC(C)(C)C(=O)OC(C)(C)C)c2csc(NC(=O)OC(C)(C)C)n2)C1=O,,ClC(Cl)Cl,,,,test
US20120053206A1,CCOC(=O)c1c(C)c2ccc(C(F)(F)F)cc2n(C)c1=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)c1c(C)c2ccc(C(F)(F)F)cc2n(C)c1=S,,Cc1ccccc1,,CCCCCC,CCOC(C)=O,test
US06492364B1,COC(=O)CCC(=O)C(=O)OC.Nc1ccccc1N>>COC(=O)CCc1nc2ccccc2nc1O,,CO,,,,test
US20070265286A1,COc1cc2c(Nc3c(F)cc(Cl)cc3F)ncnc2cc1OCc1ccccc1>>COc1cc2c(Nc3c(F)cc(Cl)cc3F)ncnc2cc1O,,O=C(O)C(F)(F)F,,,,test
US20020143029A1,CN1Cc2cc(N)cnc2C(C)(C)C1.O=C(Cl)c1ccccc1>>CN1Cc2cc(NC(=O)c3ccccc3)cnc2C(C)(C)C1.Cl,,C1CCOC1,,,,test
US20040186103A1,Cc1ccc(NC(=O)C(C)C)cc1C1=CCN(C(=O)OC(C)(C)C)CC1>>Cc1ccc(NC(=O)C(C)C)cc1C1CCN(C(=O)OC(C)(C)C)CC1,[Pd],CCO,,[H][H],,test
US20110178060A1,BrCc1ccccc1.O=C(O)C1CCOCC1>>O=C(OCc1ccccc1)C1CCOCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04824843,COc1ccc([N+](=O)[O-])cc1C=CC1=NC(C)(C)CO1>>COc1ccc(N)cc1CCC1=NC(C)(C)CO1,[Ni],CO,,[H][H],,test
US20100210639A1,C1COCCN1.Clc1ncnc2[nH]c3cnccc3c12>>c1cc2c(cn1)[nH]c1ncnc(N3CCOCC3)c12,,CN1CCCC1=O,,CCN(CC)CC,,test
US20110124597A1,CC(C)(C)OC(=O)NCC1OB(O)c2c(OCCCBr)cccc21.O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O>>CC(C)(C)OC(=O)NCC1OB(O)c2c(OCCCN3CCN(c4cc5c(cc4F)c(=O)c(C(=O)O)cn5C4CC4)CC3)cccc21,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20160235065A1,Cc1cccc(-n2nnn(C)c2=O)c1CBr.Oc1cccc(Br)c1>>Cc1cccc(-n2nnn(C)c2=O)c1COc1cccc(Br)c1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20060040999A1,CC[N+](=O)[O-].O=Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(C(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)[N+](=O)[O-],,CCO,,CC(=O)O,[Na+].[OH-],test
US20010041802A1,Nc1ccc2c(c1Br)c(=O)oc1cccc(OC(F)F)c12.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OCc1ccccc1>>O=C(Nc1ccc2c(c1Br)c(=O)oc1cccc(OC(F)F)c12)OCc1ccccc1,,C1CCOC1,,,,test
US04874760,CCOC(=O)C1=C(C)Nc2snc(CCOC(=O)[C@@H](OC)c3ccccc3)c2C1c1cccc([N+](=O)[O-])c1>>CCOC(=O)C1=C(C)Nc2snc(CCO)c2C1c1cccc([N+](=O)[O-])c1,,CCO,,[K+].[OH-],,test
US05631373,CC[O-].O=c1[nH]c2cc(F)c(F)c([N+](=O)[O-])c2[nH]c1=O>>CCOc1c(F)cc2[nH]c(=O)c(=O)[nH]c2c1[N+](=O)[O-],,O,,Cl,,test
US20150105369A1,COc1nc2ccc(Br)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1.Cn1nncc1C=O>>COc1nc2ccc(C(O)c3cnnn3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1,,C1CCOC1,,[Li]CCCC,,test
US04801584,CNn1cc(C(=O)O)c(=O)c2cc(F)c(F)c(O)c21.O=C(n1ccnc1)n1ccnc1>>CNn1cc(C(=O)O)c(=O)c2cc(F)c(-n3ccnc3)c(O)c21,,CN(C)C=O,,,,test
US04625026,CCOC(=O)C1CCc2ccccc2C1=O.N=C(N)N>>Nc1nc2c(c(=O)[nH]1)CCc1ccccc1-2,,Cc1ccccc1C,,O=C(O)O,,test
US05194472,O=C(OOC(=O)c1ccccc1)c1ccccc1.O=C1CCC(=O)N1Br.c1ccc(C2OCCO2)cc1>>O=C(OCCBr)c1ccccc1,,ClC(Cl)(Cl)Cl,,,,test
US20070117798A1,COC(=O)[C@H]1CCCC(=O)N1C(=O)OC(C)(C)C.Fc1cc([Mg]Br)cc(F)c1F>>COC(=O)[C@@H](CCCC(=O)c1cc(F)c(F)c(F)c1)NC(=O)OC(C)(C)C,,C1CCOC1,,CCOC(C)=O,[Cl-].[NH4+],test
US05104869,CC(C)(C)NC(=O)C[C@@H](Cc1ccccc1)C(=O)O.CC(C)C[C@H](NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](O)c1nccs1>>CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](CC(=O)NC(C)(C)C)Cc1ccccc1)[C@@H](O)c1nccs1,,ClCCl,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20100125062A1,C[Mg]Br.O=C1C=C(c2cccnc2F)CC1>>CC1(O)C=C(c2cccnc2F)CC1,,C1CCOC1,O,,,test
US20150218172A1,Cc1cc(C)n(CC(=O)Nc2cc(C(=O)c3cn(COCC[Si](C)(C)C)c4ncncc34)ccn2)n1>>Cc1cc(C)n(CC(=O)Nc2cc(C(=O)c3c[nH]c4ncncc34)ccn2)n1,,O=C(O)C(F)(F)F,,,,test
US20100190763A1,CC(C)(C)OC(=O)N1CCN2c3ncc(CN4CCN(c5ccc(Cl)cc5)CC4)cc3NC(=O)C2C1>>O=C1Nc2cc(CN3CCN(c4ccc(Cl)cc4)CC3)cnc2N2CCNCC12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120316192A1,CCOC(=O)C#CC(=O)OCC.Cc1c(OCc2ccccc2)ccc2c(=O)c(C=O)coc12.NCCc1c[nH]c2ccccc12>>COC(=O)C1=CC(C(=O)c2ccc(OCc3ccccc3)c(C)c2O)=CN2CCc3c([nH]c4ccccc34)C12C(=O)OC,,Cc1ccccc1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150175602A1,CC(=O)OC(C)=O.CC1NCCc2nc(N3CCC(Oc4ccc(F)cc4F)CC3)c(NCC(F)F)nc21.O=C(O)C(F)(F)F>>CC(=O)N1CCc2nc(N3CCC(Oc4ccc(F)cc4F)CC3)c(NCC(F)F)nc2C1C.O=C(O)C(F)(F)F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090197871A1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(C)c(-c3cccc(C=O)c3)c2)c1.CN1CCCNCC1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(C)c(-c3cccc(CN4CCCN(C)CC4)c3)c2)c1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140275179A1,CCOC(=O)CCc1cc(C(F)(F)F)c(OC)c(C(F)(F)F)c1>>CCOC(=O)CCc1cc(C(F)(F)F)c(O)c(C(F)(F)F)c1,,ClCCl,,BrB(Br)Br,,test
US20140329821A1,O=C(O)c1ccc(-c2nc3ccc(O)cc3[n+]([O-])n2)cc1>>O=C(O)c1ccc(-c2nnc3cc(O)ccc3n2)cc1,,CCO,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20040044008A1,Cc1ccc(Cl)cc1Br.OB(O)c1ccc(C(F)(F)F)cc1>>Cc1ccc(Cl)cc1-c1ccc(C(F)(F)F)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20070105904A1,C#Cc1cccnc1N.ON=C(Cl)Cc1ccc(Oc2cccc(F)c2)nc1>>Nc1ncccc1-c1cc(Cc2ccc(Oc3cccc(F)c3)nc2)no1,,O,,C1CCOC1,CCN(CC)CC,test
US20150166564A1,COCCN1C[C@@H](NC(=O)Nc2c(C)c(OCCO[Si](C)(C)C(C)(C)C)nn2-c2ccccc2)[C@H](c2ccc(F)c(F)c2)C1.Cl>>COCCN1C[C@@H](NC(=O)Nc2c(C)c(OCCO)nn2-c2ccccc2)[C@H](c2ccc(F)c(F)c2)C1.Cl,,ClCCl,,,,test
US20070155808A1,Cc1oc(=O)oc1CCl.O=C(O)CCc1ccc(OCc2ccc(CN(CCc3ccccc3)c3nc(-c4ccccc4)cs3)cc2)cc1>>Cc1oc(=O)oc1COC(=O)CCc1ccc(OCc2ccc(CN(CCc3ccccc3)c3nc(-c4ccccc4)cs3)cc2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070191603A1,CCCO.CCOC(C)=O.COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccc(Br)c(C#N)c3)cc21>>CCCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2cc(Cl)ccc2OC)CCO3)cc1C#N,,CCCO,,CCN(CC)CC,,test
US07217714B1,CS(=O)(=O)Cl.N#CCc1ccc(N)cc1>>CS(=O)(=O)Nc1ccc(CC#N)cc1,,ClCCl,,CCN(CC)CC,,test
US20080015203A1,Cc1nsc(NC(=O)c2cc(Oc3ccc(C(=O)N4CCC4)cc3F)cc(O[C@@H](C)CO[Si](C)(C)C(C)(C)C)c2)n1>>Cc1nsc(NC(=O)c2cc(Oc3ccc(C(=O)N4CCC4)cc3F)cc(O[C@@H](C)CO)c2)n1,,CO,,Cl,O=C([O-])O.[Na+],test
US05686424,COc1cc(C(=O)CC(C)(CCc2ccccc2)NC(=O)[C@@H]2CCCN2)cc(OC)c1OC.Cl>>COc1cc(C(=O)CC(C)(CCc2ccccc2)NC(=O)[C@@H]2CCCN2)cc(OC)c1OC.Cl,,CCOCC,,,,test
US20140243374A1,CC1CCCC(N)C1.O=S(=O)(Cl)c1ccc(Cl)cc1>>CC1CCCC(NS(=O)(=O)c2ccc(Cl)cc2)C1,,ClCCl,,CCN(CC)CC,,test
US20150093655A1,Cc1nccn1C.OCCCl>>Cc1n(C)cc[n+]1CCO.[Cl-],,Cc1ccccc1,,,,test
US07094789B2,CC(C)(C)OC(=O)N1CCC(Nc2cccc3c(Cl)nccc23)CC1.CCO.Cl>>Cl.Oc1nccc2c(NC3CCNCC3)cccc12,,CCOCC,,,,test
US20110028493A1,CCOC(=O)c1cnn(CC(N)=S)c1.O=C(CBr)c1cccc(Br)c1>>CCOC(=O)c1cnn(Cc2nc(-c3cccc(Br)c3)cs2)c1,,CCO,,,,test
US04042621,CN(C)C=O.CN(C)c1ccccc1>>CN(C=O)c1ccccc1,,CN(C)C=O,,O=O,,test
US20070219212A1,Cc1c(OCc2ccccc2)cc(C#N)cc1[N+](=O)[O-]>>Cc1c(N)cc(C#N)cc1OCc1ccccc1,[Fe],CCO,,CC(=O)O,,test
US20050239832A1,CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CN[C@H]1CCOc2ccc(CC(C)C)cc21.Cl>>CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CN[C@H]1CCOc2ccc(CC(C)C)cc21.Cl,,CO,,,,test
US06040345,CC(Oc1c(Cl)cc([N+](=O)[O-])cc1Cl)C(F)(F)C(F)(F)F>>CC(Oc1c(Cl)cc(N)cc1Cl)C(F)(F)C(F)(F)F,[Fe],CCO,,Cl,O,test
US20070249031A1,CS(=O)(=O)c1nc(Cl)cc(Cl)n1.O=C(Nc1ccc(S)cc1)C1CCCC1>>O=C(Nc1ccc(Sc2nc(Cl)cc(Cl)n2)cc1)C1CCCC1,,CC#N,,CCN(CC)CC,O,test
US20050043354A1,CC(=O)N1CCC(NC2CCCN(C(=O)OC(C)(C)C)C2Cc2ccccc2)CC1>>CC(=O)N1CCC(NC2CCCNC2Cc2ccccc2)CC1,,CC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US05237063,Fc1nc(OC(F)(F)F)c(Cl)c(C(F)(F)F)n1.N>>Nc1nc(OC(F)(F)F)cc(C(F)(F)F)n1,,CCOCC,,,,test
US20080305361A1,CC(C)=O.CC(C)C(=O)C(=O)c1ccc(F)cc1.NCCN>>CC(C)c1cnc(-c2ccc(F)cc2)c(C(C)C)n1,,O,,CCO,[K+].[OH-],test
US20050227995A1,CCN(CC)C(=O)OCC(C)C(Sc1ccc(Cl)cc1)c1cc(F)ccc1F.O=C(OO)c1cccc(Cl)c1>>CCN(CC)C(=O)OCC(C)C(c1cc(F)ccc1F)S(=O)c1ccc(Cl)cc1,,ClCCl,,O=C([O-])O.[Na+],,test
US20070066632A1,CN(C)CCN.Oc1nc(-c2cc(Cl)ccc2F)nc2nc(F)ccc12>>CN(C)CCNc1ccc2c(O)nc(-c3cc(Cl)ccc3F)nc2n1,,CC(C)O,,,,test
US20110071150A1,COC(=O)c1ccc(-c2ccc3[nH]c(-c4ccccc4Cl)cc3c2)c(C)c1>>Cc1cc(C(=O)O)ccc1-c1ccc2[nH]c(-c3ccccc3Cl)cc2c1,,CCO,O,[K+].[OH-],,test
US20120122848A1,O=C(OCc1ccccc1)N1CC[C@]23CCCC[C@H]2[C@H]1Cc1c3cc(OCc2ccccc2)c(Nc2ccccc2[N+](=O)[O-])c1Br>>Nc1ccccc1Nc1c(OCc2ccccc2)cc2c(c1Br)C[C@@H]1[C@@H]3CCCC[C@]23CCN1C(=O)OCc1ccccc1,[Ni],CO,,NN,O,test
US04482560,CC(CCl)CN1CCC(c2ccccc2)CC1.O=C1CCc2c(O)c(Cl)cc(Cl)c2N1>>CC(COc1c(Cl)cc(Cl)c2c1CCC(=O)N2)CN1CCC(c2ccccc2)CC1,,CN(C)C=O,,CO,[K+].[OH-],test
US20050261276A1,CNCCC(C)C(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1.CS(=O)(=O)Cl>>CC(CCN(C)S(C)(=O)=O)C(c1cc(F)ccc1F)S(=O)(=O)c1ccc(Cl)cc1,,ClCCl,,c1ccncc1,,test
US20140142085A1,COP(=O)(OC)C(=[N+]=[N-])C(C)=O.NC(=O)c1cc(-c2cccnc2[C@H](Cc2cc(F)cc(F)c2)NC(=O)Cn2cc(C=O)c(C(F)(F)F)n2)ccc1F>>C#Cc1cn(CC(=O)N[C@@H](Cc2cc(F)cc(F)c2)c2ncccc2-c2ccc(F)c(C(N)=O)c2)nc1C(F)(F)F,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20120142686A1,CNC(=O)c1c2cc(C3CC3)c(N(CCN)S(C)(=O)=O)cc2nn1-c1ccc(Br)cc1.O=C(O)Cc1nnn[nH]1>>CNC(=O)c1c2cc(C3CC3)c(N(CCNC(=O)Cc3nn[nH]n3)S(C)(=O)=O)cc2nn1-c1ccc(Br)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080019915A1,CCc1ccc(NC(=O)C(C)(C)C)nc1Cl>>CCc1ccc(N)nc1Cl,,Cl,,[Na+].[OH-],,test
US20150335634A1,CC=O.NCCc1ccc(O)c(O)c1>>C[C@@H]1NCCc2cc(O)c(O)cc21,,CO,,Cl,,test
US20040024034A1,C=CCc1ccccc1O.CCOC(=O)CBr>>C=CCc1ccccc1OCC(=O)OCC,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060084680A1,CCOC(=O)C[C@@H]1CCc2cc(O)ccc21.OCCCNc1nc(Cl)ccc1C(F)(F)F>>CCOC(=O)C[C@@H]1CCc2cc(OCCCNc3nc(Cl)ccc3C(F)(F)F)ccc21,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20130211075A1,CC(C)S(=O)(=O)Cl.Cc1cc(NC(=O)c2cnn(-c3ccc(C(F)(F)F)cn3)c2C)cnc1C1=CCNCC1>>Cc1cc(NC(=O)c2cnn(-c3ccc(C(F)(F)F)cn3)c2C)cnc1C1=CCN(S(=O)(=O)C(C)C)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150182503A1,CCC(c1ccc(C(F)(F)F)cc1)(C(C)O)n1ncc2c(NC(c3ccccc3)(c3ccccc3)c3ccccc3)cc(F)cc21>>CCC(c1ccc(C(F)(F)F)cc1)(C(C)O)n1ncc2c(N)cc(F)cc21,,CO,Cl,O=C([O-])O.[Na+],,test
US05284853,CCCCc1nc(=O)c2cc(C=O)ccc2[nH]1.C[Mg]Br>>CCCCc1nc(=O)c2cc(C(C)O)ccc2[nH]1,,C1CCOC1,CCOCC,,,test
US20010011135A1,Cc1ccc(C)n1-c1ccc(C(C)(C)C)cc1[N+](=O)[O-]>>Cc1cc(-c2ccc(C(C)(C)C)cc2N)c(C)[nH]1,[Pd],,,CCOC(C)=O,,test
US20100113421A1,CCOC(=O)c1[nH]c(C)c(S(=O)(=O)N2CCCC2)c1C.O=S(=O)(Cl)Cl>>CCOC(=O)c1[nH]c(C=O)c(S(=O)(=O)N2CCCC2)c1C,,ClCCl,,,,test
US20110039831A1,CC(C)NN=Cc1c(F)cc(F)cc1F>>CC(C)n1ncc2c(F)cc(F)cc21,,Cc1cc(C)cc(C)c1,,O=C([O-])[O-].[K+].[K+],,test
US20040186132A1,COC(=O)c1cc([N+](=O)[O-])ccc1Br.COc1ccc(Cl)cc1B(O)O>>COC(=O)c1cc([N+](=O)[O-])ccc1-c1cc(Cl)ccc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20090124596A1,CN(C)Cc1ccc(-c2cccc(-n3c(=O)n([C@H]4CC[C@@H](NC(=O)OC(C)(C)C)CC4)c(=O)c4cc(F)cnc43)c2)cc1>>CN(C)Cc1ccc(-c2cccc(-n3c(=O)n([C@@H]4CC[C@H](N)CC4)c(=O)c4cc(F)cnc43)c2)cc1,,C1COCCO1,,Cl,,test
US20100317651A1,CC(C)N(C)c1nc2c(nc1Br)CN(Cc1ccccc1)CCO2.CC(Cl)OC(=O)Cl>>CC(C)N(C)c1nc2c(nc1Br)CNCCO2.Cl,,Cc1ccccc1,,,,test
US20100120760A1,CI.CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(NS(C)(=O)=O)c3c(c12)CC(C)O3>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c3c(c12)CC(C)O3,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100317645A1,C[Mg]Br.N#Cc1ccc2c(c1)N(S(=O)(=O)c1ccc(OC(F)(F)F)cc1)Cc1ccc(C(F)(F)F)nc1N2.O=C([O-])O>>CC(=O)c1ccc2c(c1)N(S(=O)(=O)c1ccc(OC(F)(F)F)cc1)Cc1ccc(C(F)(F)F)nc1N2,,C1CCOC1,,Cl,,test
US20120201783A1,COC(=O)C(=O)NCC(C)=O>>COC(=O)c1ncc(C)o1,,O=P(Cl)(Cl)Cl,,,,test
US20150152127A1,CN(C(=O)OC(C)(C)C)C1=N[C@H]2[C@H](O[C@H]([C@@H](O)C(F)(F)F)[C@@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)S1.O=[N+]([O-])c1ccc(F)cc1>>CN(C(=O)OC(C)(C)C)C1=N[C@H]2[C@H](O[C@H]([C@@H](Oc3ccc([N+](=O)[O-])cc3)C(F)(F)F)[C@@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)S1,,CN(C)C=O,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05849911,CC(C)COC(=O)Cl.O=C(O)c1ccc(-c2ccccn2)cc1>>CC(C)COC(=O)OC(=O)c1ccc(-c2ccccn2)cc1,,C1CCOC1,,CN1CCOCC1,,test
US20110251169A1,CC(C)(O)CN.Clc1ccc(C#Cc2ccccc2)nn1>>CC(C)(O)CNc1ccc(C#Cc2ccccc2)nn1,,c1ccncc1,,,,test
US20080221110A1,C=C(C(=O)OC)c1c(F)ccc2ccc(OC)nc12.O=C(NC[C@H]1CCNC1)C(F)(F)F>>COC(=O)C(CN1CC[C@H](CNC(=O)C(F)(F)F)C1)c1c(F)ccc2ccc(OC)nc12,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20100105655A1,COCCN1CCN(CCOc2ccc([N+](=O)[O-])c(OC)c2)CC1>>COCCN1CCN(CCOc2ccc(N)c(OC)c2)CC1,O=[Pt]=O,,,,,test
US05679683,CCOC(=O)CC#N.COc1ccc([N+](=O)[O-])c(F)c1>>CCOC(=O)C(C#N)c1cc(OC)ccc1[N+](=O)[O-],,C1CCOC1,O,Cl,CC(C)(C)[O-].[K+],test
US20110200549A1,CC(=O)Nc1ccccc1.CCCCCI>>CCCCCN(C(C)=O)c1ccccc1,,CS(C)=O,,[K+].[OH-],,test
US06166006,CCOC(=O)C1CCN(C)CC1.O=C(Nc1ccc(CCl)cc1)C1=Cc2cc(-c3ccccc3)ccc2CC1>>CCOC(=O)C1CC[N+](C)(Cc2ccc(NC(=O)C3=Cc4cc(-c5ccccc5)ccc4CC3)cc2)CC1.[Cl-],,CN(C)C=O,,,,test
US20040220169A1,COC[C@H]1CCCN1.O=C(NCc1nc2cc(Cl)ccc2[nH]1)c1ccc(C(=O)O)c(Cl)c1>>COC[C@H]1CCCN1C(=O)c1ccc(C(=O)NCc2nc3cc(Cl)ccc3[nH]2)cc1Cl,,CS(C)=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20030166639A1,Cc1cc(-c2cccc(C(=O)CC(=O)Nc3cc(C(F)(F)F)c(OCC(F)(F)F)cc3NC(=O)OC(C)(C)C)c2)ccn1>>Cc1cc(-c2cccc(C3=Nc4cc(OCC(F)(F)F)c(C(F)(F)F)cc4NC(=O)C3)c2)ccn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04451476,CCC(=O)c1ccc(OCCCCCCCc2cc(C)no2)cc1.NO>>CCC(=NO)c1ccc(OCCCCCCCc2cc(C)no2)cc1,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20080167356A1,COC(=O)c1ccc2ccc(-c3ccc(OCc4c(CCc5c(Cl)cccc5Cl)noc4C(C)C)cc3)cc2c1>>CC(C)c1onc(CCc2c(Cl)cccc2Cl)c1COc1ccc(-c2ccc3ccc(C(=O)O)cc3c2)cc1,,C1CCOC1,,CO,[Na+].[OH-],test
US20140100229A1,CCOC(=O)C(C)(Br)C(=O)OCC.N#CCC#N>>CCOC(=O)C(C)(C(=O)OCC)C(C#N)C#N,,C1CCOC1,CCOC(C)=O,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US20130296349A1,N#CCc1nc(=O)c2cc(Cl)ccc2[nH]1.O=C(Cl)c1ccc(Cl)cc1Cl>>N#C/C(C(=O)c1ccc(Cl)cc1Cl)=C1/NC(=O)c2cc(Cl)ccc2N1,,C1COCCO1,,CCN(CC)CC,,test
US20100069336A1,Br.CC(=O)N[C@@H](Cc1ccc(N(CCCl)CCCl)cc1)C(=O)O.CCN(CC)CCBr>>Br.CCN(CC)CCOC(=O)[C@H](Cc1ccc(N(CCCl)CCCl)cc1)NC(C)=O,,CC#N,CCOC(C)=O,[Na],,test
US05710164,N#CCc1cccnc1.O=Cc1ccc2c(c1)OCCO2>>N#CC(=Cc1ccc2c(c1)OCCO2)c1cccnc1,,CCO,,C[O-].[Na+],,test
US20020119260A1,CCCCC[C@@H]1CC[C@@H]([C@H]2CC[C@H](C=O)CC2)CC1.CCOC(=O)CP(CC)CC>>CCCCC[C@@H]1CC[C@@H]([C@H]2CC[C@H](C=CC(=O)OCC)CC2)CC1,,C1CCOC1,Cc1ccccc1,O,CC(C)(C)[O-].[K+],test
US20100292210A1,COC(CN(C)C(=O)c1ccc(Cl)nc1Cl)OC>>CN(CC=O)C(=O)c1ccc(Cl)nc1Cl,,ClC(Cl)Cl,,O,O=C(O)C(F)(F)F,test
US20050197351A1,C1CCNCC1.COC(=O)C=Cc1ccccc1N=C=Nc1ccccc1>>COC(=O)CC1c2ccccc2N=C(N2CCCCC2)N1c1ccccc1,,c1ccccc1,,,,test
US20150065717A1,N#Cc1ccc(Cl)cc1F.OCC(F)(F)F>>N#Cc1ccc(Cl)cc1OCC(F)(F)F,,C1CCOC1,,Cl,[H-].[Na+],test
US20100331353A1,CC(C)(C)OC(=O)N1CCC2(CCNCC2)CC1.COc1cc(C(=O)O)ccc1F>>COc1cc(C(=O)N2CCC3(CCN(C(=O)OC(C)(C)C)CC3)CC2)ccc1F,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130261107A1,COC(=O)c1nc2c(s1)CN(C(=O)c1ccccc1F)CC2>>O=C(c1ccccc1F)N1CCc2nc(CO)sc2C1,,CO,O,[BH4-].[Na+],,test
US20080312226A1,Fc1ccc(-c2csc(N3CCNCC3)n2)cc1.O=C(Nc1cccnc1)OCC(Cl)(Cl)Cl>>O=C(Nc1cccnc1)N1CCN(c2nc(-c3ccc(F)cc3)cs2)CC1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20110201609A1,CCOC(=O)CS.O=C(O)CSc1cc(NS(=O)(=O)c2cccs2)c2ccccc2c1O.O=C1C(Cl)=CC(=NS(=O)(=O)c2cc(Cl)c(Cl)s2)c2ccccc21>>COC(=O)CCSc1cc(NS(=O)(=O)c2cc(Cl)c(Cl)s2)c2ccccc2c1O,,CCOC(C)=O,,,,test
US20020052498A1,CCCCCCCCCCCCCCCCCCNC(=O)Oc1ccccc1CCC(=O)NCCCN(C)C.Cl>>CCCCCCCCCCCCCCCCCCNC(=O)Oc1ccccc1CCC(=O)NCCCN(C)C.Cl,,CCOC(C)=O,,,,test
US04012524,CC1(Cc2ccccc2)Cc2cc(O)c(Cl)c(Cl)c2C1O.CCOC(=O)CBr>>CC1(Cc2ccccc2)Cc2cc(OCC(=O)O)c(Cl)c(Cl)c2C1O,,CN(C)C=O,,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US04857659,BrCCCSc1ccccc1.CCC(=O)Cl>>CCC(=O)c1ccc(SCCCBr)cc1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US04440927,Cc1cc(C)c(CO)c(-c2ccc(F)c(C)c2)c1.O=S(Cl)Cl>>Cc1cc(C)c(CCl)c(-c2ccc(F)c(C)c2)c1,,Cc1ccccc1,,,,test
US20160002248A1,NCc1ccccn1.O=C(O)c1cn(CCCCc2cc3cc(C4CC4)[nH]c3nn2)nn1>>O=C(NCc1ccccn1)c1cn(CCCCc2cc3cc(C4CC4)[nH]c3nn2)nn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080193411A1,Nc1cc(Br)cnc1NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1>>O=C(OCc1ccccc1)N1CCC[C@H]1c1nc2ncc(Br)cc2[nH]1,,CC(=O)O,,,,test
US05599832,Clc1ccc(-c2cc3cc(Cl)cc(Cl)c3[nH]2)cc1.O=S(Cl)Cl>>Clc1ccc(-c2[nH]c3c(Cl)cc(Cl)cc3c2Cl)cc1,,C1CCOC1,,,,test
US20050107381A1,CCCC(NC(=O)OC(C)(C)C)C(=O)Nc1ccc(C(C)=CC(C)=O)cn1>>CCCC(NC(=O)OC(C)(C)C)C(=O)Nc1ccc(C(C)CC(C)=O)cn1,O=[Pt]=O,CCOC(C)=O,,,,test
US05496930,C=COC(=O)CCl.O=C(OC[C@H]1OC=C[C@@H](O)[C@@H]1O)c1ccccc1>>O=C(CCl)O[C@@H]1C=CO[C@H](COC(=O)c2ccccc2)[C@H]1O,,COCCOC,,,,test
US20030149027A1,CC(C)(C)OC(=O)NCc1ccc(N2C(=O)C(CC(=O)NCc3ccccc3F)C(=O)N(Cc3ccc(NC(=O)c4ccccc4)cc3)c3ccccc32)cc1.Cl>>Cl.NCc1ccc(N2C(=O)C(CC(=O)NCc3ccccc3F)C(=O)N(Cc3ccc(NC(=O)c4ccccc4)cc3)c3ccccc32)cc1,,CCOC(C)=O,,,,test
US20110263588A1,Cn1nc(C(=O)Nc2cccc(Cl)c2)c2cnc3ccccc3c21>>Cn1nc(C(=O)Nc2cccc(Cl)c2)c2c1-c1ccccc1NC2,,C1CCOC1,CCO,[BH4-].[Na+],,test
US20070244095A1,CB(O)O.Cc1c(Br)ccc2c1N(C(=O)OC(C)C)CCCC2=O>>Cc1ccc2c(c1C)N(C(=O)OC(C)C)CCCC2=O,,C1COCCO1,,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],test
US20150025065A1,O=C(OCc1ccccc1)N1CC2CS(=O)(=NC(=O)C(F)(F)F)CC2C1>>N=S1(=O)CC2CN(C(=O)OCc3ccccc3)CC2C1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20100041646A1,CC(C)(C)[Si](C)(C)OCCCNc1ccc(N2C[C@H](CNC(=O)c3ccc(Cl)s3)OC2=O)cc1.N#CBr>>CC(C)(C)[Si](C)(C)OCCCN(C#N)c1ccc(N2C[C@H](CNC(=O)c3ccc(Cl)s3)OC2=O)cc1,,C1CCOC1,ClCCl,O,O=C([O-])O.[Na+],test
US05547983,COC(=O)c1ccc2cc(-c3ccc(OCCCO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1>>O=C(O)c1ccc2cc(-c3ccc(OCCCO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1,,CCCCO,,[K+].[OH-],,test
US20140200231A1,NCCC(=O)N1CCc2nc(NC3Cc4ccccc4C3)ncc2C1.O=C(O)c1cn[nH]n1>>O=C(NCCC(=O)N1CCc2nc(NC3Cc4ccccc4C3)ncc2C1)c1c[nH]nn1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US04997831,NN1CCOc2ccccc21.O=C1CCNC(=O)C1>>O=C1NCCc2c1c1cccc3c1n2CCO3,,CCO,,,,test
US20110009354A1,Cc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CCl)[C@@H](O)[C@H]1O.c1ccncc1>>CCc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CCl)[C@@H](O)[C@H]1O,,CC#N,,O=S(Cl)Cl,,test
US20160136172A1,NC(=O)c1ccc(Cl)nc1N.O=Cc1cccc(F)c1>>O=C1NC(c2cccc(F)c2)Nc2nc(Cl)ccc21,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20110053909A1,CC(C)(C)[Si](C)(C)Cl.OCCOCc1cccc(Br)c1>>CC(C)(C)[Si](C)(C)OCCOCc1cccc(Br)c1,,ClCCl,,c1c[nH]cn1,,test
US20080318947A1,C[C@@H](CO)N(C(=O)[O-])C(C)(C)C.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC[C@H](C)NC(=O)OC(C)(C)C)cc1,,ClCCl,,CCN(CC)CC,CN(C)c1ccccn1,test
US20050124654A1,CS(=O)(=O)Cl.O=C(CC(NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccc(F)cc1)NC1CCCc2nc(CCO)ncc21>>CS(=O)(=O)OCCc1ncc2c(n1)CCCC2NC(=O)CC(NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1ccc(F)cc1,,ClCCl,,CCN(CC)CC,,test
US20120015940A1,CO[C@@]12CCN(C(=O)O[C@@H](C)C(F)(F)F)[C@@H]1CN(C(=O)OC(C)(C)C)C2>>CO[C@@]12CCN(C(=O)O[C@@H](C)C(F)(F)F)[C@@H]1CNC2,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20060293319A1,CN=C=O.O=C1Nc2cc(Cl)ccc2C1(Cc1cccc(Cl)c1)C1CCCNC1>>CNC(=O)N1CCCC(C2(Cc3cccc(Cl)c3)C(=O)Nc3cc(Cl)ccc32)C1,,ClCCl,,CCN(CC)CC,,test
US04394515,CN(C)CCO.O=C(Cl)c1ccc2c(c1)Sc1ccccc1CC2=O>>CN(C)CCOC(=O)c1ccc2c(c1)Sc1ccccc1CC2=O,,C1CCOC1,,,,test
US20110152285A1,CCOC(=O)c1[nH]c(C)cc1-c1ccccc1.O=C1CCC(=O)N1Br>>CCOC(=O)c1[nH]c(C)c(Br)c1-c1ccccc1,,C1COCCO1,CC(=O)O,,,test
US20090270405A1,O=C(O)C(F)(F)S(=O)(=O)F.O=[N+]([O-])c1ccc(O)nc1>>O=[N+]([O-])c1ccc(OC(F)F)nc1,,CC#N,,O=S(=O)([O-])[O-].[Na+].[Na+],,test
US20100249085A1,Cc1ccc(Cn2nc(C(=O)O)cc2C)cc1.N>>Cc1ccc(Cn2nc(C(N)=O)cc2C)cc1,CN(C)C=O,C1COCCO1,ClCCl,O=C(Cl)C(=O)Cl,,test
US20060058513A1,O=C(O)C=CC(=O)NCCCCCC(=O)O>>O=C(O)CCCCCN1C(=O)C=CC1=O,,CC(=O)OC(C)=O,,CC(=O)[O-].[Na+],,test
US20120232068A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Nc1ncc(Br)cc1S(N)(=O)=O>>CC1(C)OB(c2cnc(N)c(S(N)(=O)=O)c2)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US05442060,CC(=O)Cl.CCCCCC(CC(=O)OCC)c1cccc(OC)c1OC>>CCCCCC(CC(=O)OCC)c1cc(C(C)=O)cc(OC)c1OC,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20110190257A1,CSc1ccc(Nc2c(C(=O)NOC[C@H]3COC(C)(C)O3)ccc3cnsc23)c(F)c1>>CSc1ccc(Nc2c(C(=O)NOC[C@H](O)CO)ccc3cnsc23)c(F)c1,,CO,,Cl,,test
US04329470,CCOC(=O)c1c(CBr)n(C(C)=O)c(=O)n1C(C)=O>>CCOC(=O)c1c(CBr)[nH]c(=O)n1C(C)=O,,Br,CC(=O)O,,,test
US20140200344A1,CCOP(=O)(CC#N)OCC.O=C1CCC(c2nnn3cnc4[nH]ccc4c23)CC1>>N#CC=C1CCC(c2nnn3cnc4[nH]ccc4c23)CC1,,C1CCOC1,,O,[H-].[Na+],test
US05597823,CCOC(=O)CS.N#Cc1cc([N+](=O)[O-])ccc1Cl>>COC(=O)c1sc2ccc([N+](=O)[O-])cc2c1N,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US04621084,CC(=O)OCCBr.Cc1c(-c2ccc3sc(=O)[nH]c3c2)nc2ccccn12>>CC(=O)OCCn1c(=O)sc2ccc(-c3nc4ccccn4c3C)cc21,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20050277678A1,COc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(SC)cc2)cc1F.O=C(OO)c1cccc(Cl)c1>>COc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(C)=O)cc2)cc1F,,ClC(Cl)Cl,,,,test
US05962002,CC(=O)OC1=C(CCC(C)(C)C)C(=O)c2ccccc2C1=O>>CC(C)(C)CCC1=C(O)C(=O)c2ccccc2C1=O,,C1CCOC1,,[Na+].[OH-],,test
US20100256092A1,N#Cc1ccc(Cl)nc1.OB1OCc2ccc(O)cc21>>N#Cc1ccc(Oc2ccc3c(c2)B(O)OC3)nc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020055632A1,CO.Fc1cc(F)c(COC[C@@H]2C[C@@H](SC(c3ccccc3)(c3ccccc3)c3ccccc3)CN2c2ccnc(Cl)n2)cc1F>>COc1nccc(N2C[C@H](SC(c3ccccc3)(c3ccccc3)c3ccccc3)C[C@H]2COCc2cc(F)c(F)cc2F)n1,,CO,,C[O-].[Na+],,test
US20040122063A1,C1=CCCCCCC1.C[N+]1([O-])CCOCC1.O=[Os](=O)(=O)=O>>O[C@H]1CCCCCC[C@H]1O,O=[Os](=O)(=O)=O,CC#N,,O,,test
US20080275037A1,Clc1ncnc2c1CN(Cc1ccccc1)CC2.NCc1ccc(Cl)nc1>>Clc1ccc(CNc2ncnc3c2CN(Cc2ccccc2)CC3)cn1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20160083387A1,C=C1CC[C@H]2[C@H](O)[C@@H]([C@@]3(C)CC[C@H](O[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)C[C@@H]3CCOc3ccccn3)CC[C@]12C>>C=C1CC[C@H]2[C@H](O)[C@@H]([C@@]3(C)CC[C@H](O)C[C@@H]3CCOc3ccccn3)CC[C@]12C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120329780A1,COC(=O)c1cccc(-c2nc(Cl)c3nn(Cc4ccc(OC)cc4)cc3n2)c1.Nc1ccc2cn[nH]c2c1>>COC(=O)c1cccc(-c2nc(Nc3ccc4cn[nH]c4c3)c3[nH]ncc3n2)c1,C1COCCO1,CO,,Cl,,test
US06221865B1,CC(C)(C)OC(=O)N1CCC[C@H]1CO.O=S(=O)(Cl)c1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@H]1COS(=O)(=O)c1ccccc1,,ClCCl,O,CCN(CC)CC,CCOCC,test
US20060223850A1,Cc1noc(-c2cccnc2OCc2ccccc2)n1>>Cc1noc(-c2cccnc2O)n1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20140057906A1,O=[N+]([O-])c1ccc2[nH]c(-c3ccccn3)cc2c1>>Nc1ccc2[nH]c(-c3ccccn3)cc2c1,,CCO,,O,,test
US05834482,CCc1noc(-c2cc3c(cn2)[nH]c2ccccc23)n1.ClCCCBr>>CCc1noc(-c2cc3c4ccccc4n(CCCCl)c3cn2)n1,,CN(C)C=O,,[H][H],[H-].[Na+],test
US05874440,CCCC(=O)OC(=O)CCC.CCCOc1ccccc1-c1nc(N)cc(=O)[nH]1>>CCCOc1ccccc1-c1nc(NC(=O)CCC)cc(=O)[nH]1,,CCO,,,,test
US20050267093A1,NCc1ccccc1.O=C(CCc1ccc(CCl)cc1)Nc1ccc(-c2ccc(Cl)cc2)cc1>>O=C(CCc1ccc(CNCc2ccccc2)cc1)Nc1ccc(-c2ccc(Cl)cc2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140256933A1,O=C(NC1=N[C@@]2(c3ccccc3)CN(C(=O)OCc3ccccc3)C[C@H]2CS1)c1ccccc1>>O=C(NC1=N[C@@]2(c3ccccc3)CNC[C@H]2CS1)c1ccccc1,,CC#N,,C[Si](C)(C)I,,test
US20040192767A1,CC1(C)OBOC1(C)C.COC(=O)c1cc(CSc2ccc(Br)cc2)c(C)o1>>COC(=O)c1cc(CSc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)c(C)o1,,C1CCOC1,C1COCCO1,ClCCl,,test
US20060111375A1,C1COCCN1.COc1ccc(Oc2ccnc3cc(OCCCl)c(OC)cc23)c(C(C)=O)c1>>COc1ccc(Oc2ccnc3cc(OCCN4CCOCC4)c(OC)cc23)c(C(C)=O)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05236952,COc1cc([N+](=O)[O-])cc(C=O)c1OC>>O=Cc1cc([N+](=O)[O-])cc(O)c1O,,CC(=O)O,,Br,,test
US20040024066A1,CC(C)(C)OC(=O)N[C@@H](COCc1ccccc1)CS(=O)(=O)Cc1ccc2sccc2c1>>O=CN(O)[C@@H](COCc1ccccc1)CS(=O)(=O)Cc1ccc2sccc2c1,,C1COCCO1,,CCOCC,Cl,test
US20040242577A1,Clc1ccc(OC2CCN(CC3CNCCO3)CC2)cc1Cl.O=C(Cl)c1cn2cc(F)ccc2n1>>O=C(c1cn2cc(F)ccc2n1)N1CCOC(CN2CCC(Oc3ccc(Cl)c(Cl)c3)CC2)C1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US06136837,COC(c1cc(C)no1)c1ccccc1CO.ClC(Cl)(Cl)Cl>>COC(c1cc(C)no1)c1ccccc1CCl,,CC#N,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090105231A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)[C@H](C)NCc1ccccc1>>CCOC(=O)[C@H](C)N(Cc1ccccc1)C(=O)OC(C)(C)C,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,,test
US20090286777A1,C[C@@H](O[C@H]1CN2C(=O)C=C(c3ccncc3)C[C@H]2[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(OO)c1cccc(Cl)c1>>C[C@@H](O[C@H]1CN2C(=O)C=C(c3cc[n+]([O-])cc3)C[C@H]2[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,ClCCl,,,,test
US20050215511A1,CO[C@@H]1O[C@H](COCc2ccc(Cl)cc2Cl)[C@@H](OCc2ccc(Cl)cc2Cl)[C@@]1(C)O>>CO[C@@H]1O[C@H](COCc2ccc(Cl)cc2Cl)[C@@H](OCc2ccc(Cl)cc2Cl)[C@H]1O,,ClCCl,,,,test
US20070072925A1,CCC[Mg]Br.CON(C)C(=O)c1cccc(Br)c1>>CCCC(=O)c1cccc(Br)c1,,C1CCOC1,,,,test
US20100317659A1,Cc1cc(Nc2nc(C(=O)c3ccc(F)c(Cl)c3)nc3ccccc23)n[nH]1>>Cc1cc(Nc2nc(C(O)c3ccc(F)c(Cl)c3)nc3ccccc23)n[nH]1,,C1CCOC1,CO,[BH4-].[Na+],,test
US04707473,CC(Cl)c1ccccc1.c1ccc2c(c1)Nc1ccccc1O2>>CC(c1ccccc1)N1c2ccccc2Oc2ccccc21,,CN(C)C=O,,O,[H-].[Na+],test
US05462954,CCc1cc(-c2ccc(F)cc2)c(OCc2ccccc2)cc1OCCCOc1ccccc1CCc1nnn[nH]1>>CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1ccccc1CCc1nnn[nH]1,[Pd],CCO,,,,test
US20060074054A1,BrBr.CCOC(=O)c1cc2ccccc2n1S(=O)(=O)c1ccccc1>>Brc1cc2ccccc2[nH]1,,CN(C)C=O,,O,,test
US04789675,CC(=O)OC(C)=O.Nc1ccc2c(c1)NC(=O)C(CCCN1CCN(c3ccc(F)cc3)CC1)O2>>CC(=O)Nc1ccc2c(c1)NC(=O)C(CCCN1CCN(c3ccc(F)cc3)CC1)O2,,c1ccncc1,,,,test
US20080207654A1,CCCc1nc(C)n(CC2(O)CCOCC2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCc1nc(C)n(CC2(O)CCOCC2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US06028116,COC(Cl)Cl.COc1ccccc1F>>COc1ccc(C=O)cc1F,Cl[Ti](Cl)(Cl)Cl,ClCCl,,CCOCC,,test
US20070185089A1,COC(=O)c1cnc(N2CCC(c3ccc4c(c3)CCN(C3CCCC3)CC4)CC2)cn1>>O=C(O)c1cnc(N2CCC(c3ccc4c(c3)CCN(C3CCCC3)CC4)CC2)cn1,,CO,,Cl,[Na+].[OH-],test
US20160067691A1,C1CCNCC1.O=C(Cl)C1CCCCC1>>O=C(C1CCCCC1)N1CCCCC1,,Cc1ccccc1,,CCN(CC)CC,,test
US20060004108A1,CC1(C)C2CC[C@@]1(C)C(=O)CC2=O.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>CC1(C)C2CC[C@@]1(C)C(=O)C(C(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)C2=O,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,Cl,test
US20100099870A1,BrCc1ccccc1.COCCOc1nc(N)c2nc(OC)n(CCC3CCN(C(=O)OC(C)(C)C)CC3)c2n1>>COCCOc1nc(N)c2[nH]c(=O)n(CCC3CCN(Cc4ccccc4)CC3)c2n1,,C1CCOC1,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20150329523A1,COCCOCCOCCOc1cc(N)cc(F)c1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)cc1>>COCCOCCOCCOc1cc(F)cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)nn4-c4ccc(C)cc4)c4ccccc34)n2)c1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US05780437,CI.Cc1cc(C)cc(-c2[nH]c3ccc(-n4nn[nH]c4=O)cc3c2CCN(CCCCc2cccnc2)Cc2ccccc2)c1>>Cc1cc(C)cc(-c2[nH]c3ccc(-n4nnn(C)c4=O)cc3c2CCN(CCCCc2cccnc2)Cc2ccccc2)c1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US06245761B1,COC(=O)CCc1c(COc2ccc(Cl)cc2)n(C)c2ccccc12>>Cn1c(COc2ccc(Cl)cc2)c(CCC(=O)O)c2ccccc21,,C1CCOC1,,[Li+].[OH-],,test
US20060276465A1,CN1C(=O)COc2cc([N+](=O)[O-])c(C3=CCC(C(C)(C)C)CC3)cc21>>CN1C(=O)COc2cc(N)c(C3CCC(C(C)(C)C)CC3)cc21,[Pd],CO,,C1CCOC1,,test
US20040266820A1,Cn1c(=O)cc(C(F)(F)F)c2cc(N)ccc21.S=C=NCCc1ccc(Cl)cc1>>Cn1c(=O)cc(C(F)(F)F)c2cc(NC(=S)NCCc3ccc(Cl)cc3)ccc21,,CN1CCCC1=O,,,,test
US20050004204A1,COc1c([N+](=O)[O-])cc(Br)cc1C(C)(C)C>>CC(C)(C)c1cc(Br)cc([N+](=O)[O-])c1O,[Fe],CO,O,[Cl-].[NH4+],,test
US20040186114A1,C=C[Sn](CCCC)(CCCC)CCCC.Cc1ccccc1.Clc1nccc(Oc2ccnc(Cl)n2)n1>>C=Cc1nccc(Oc2ccnc(C=C)n2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,,,test
US05310737,CC[Si](CC)(CC)OS(=O)(=O)C(F)(F)F.C[C@@H](O)CNC(C)(C)CC(=O)N[C@@H]1CCc2ccccc2NC1=O>>CC[Si](CC)(CC)O[C@H](C)CNC(C)(C)CC(=O)N[C@@H]1CCc2ccccc2NC1=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20130150340A1,COc1ccc(Cn2ncc3c(C(=O)O)cc(-c4ccc(O)cc4)nc32)cc1>>O=C(O)c1cc(-c2ccc(O)cc2)nc2[nH]ncc12,,O=C(O)C(F)(F)F,,O,,test
US20150011546A1,BrCc1ccccc1.COC(=O)c1c[nH]nc1C>>COC(=O)c1cnn(Cc2ccccc2)c1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090023746A1,C=O.Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC3CC3)cc(CN3CCN[C@@H](CO)C3)c2c1>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC3CC3)cc(CN3CCN(C)[C@@H](CO)C3)c2c1,,ClCCl,,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20080312232A1,Cc1c(C(=O)O)c(=O)n(-c2ccccc2)n1C.ClCCl>>COC(=O)c1c(C)n(C)n(-c2ccccc2)c1=O,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20070072866A1,Nc1ccccc1NC(=O)c1cc(Cl)n[nH]c1=O>>O=c1[nH]nc(Cl)cc1-c1nc2ccccc2[nH]1,,CC(=O)O,,,,test
US04746354,CCOC(=O)C(=CNNc1c(Cl)cc(C(F)(F)F)cc1Cl)C(C)=O>>CCOC(=O)c1cnn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1C,,CCO,,O=S(=O)(O)O,,test
US20140356322A1,CC(C)(C)O[C@@H]1C[C@@H](C(=O)O)N(C(=O)OCC2c3ccccc3-c3ccccc32)C1.NCc1ccc(Cl)cc1>>CC(C)(C)O[C@@H]1C[C@@H](C(=O)NCc2ccc(Cl)cc2)N(C(=O)OCC2c3ccccc3-c3ccccc32)C1,,CCOC(C)=O,ClCCl,ClCCCl,On1nnc2ccccc21,test
US20080009486A1,C=C(C)C=NC(=C)O[Si](C)(C)C.C[Si](C)(C)CCOCN1C(=O)/C(=C\c2cccc(Cl)c2)c2ccc(Br)cc21>>C=C(C)C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Br)ccc12.COC(C)[Si](C)(C)C,,Cc1ccccc1,,CO,,test
US20120302809A1,CC(=O)c1cccc(C(C)=Nc2c(C)cccc2C(C)C)n1.CC(C)c1ccccc1N>>CC(=Nc1ccccc1C(C)C)c1cccc(C(C)=Nc2c(C)cccc2C(C)C)n1,,Cc1ccccc1,,,,test
US20050234033A1,COC(=O)c1cnc(Br)s1.NCCN1CCNCC1>>COC(=O)c1cnc(N2CCN(CCN)CC2)s1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100152168A1,CN1CCC(=O)CC1.COc1ccc(S(=O)(=O)n2c(=O)n(C(C(=O)N3CC[C@H](N)C3)c3ccccc3)c3cc(C#N)ccc32)cc1>>COc1ccc(S(=O)(=O)n2c(=O)n(C(C(=O)N3CC[C@H](NC4CCN(C)CC4)C3)c3ccccc3)c3cc(C#N)ccc32)cc1,,C1CCOC1,,,,test
US20100168418A1,COc1ccc2ncc(=O)n(CCN3CCC(NCc4cc(-c5cccs5)on4)CC3)c2c1.Cl>>COc1ccc2ncc(=O)n(CCN3CCC(NCc4cc(-c5cccs5)on4)CC3)c2c1.Cl,,CCOC(C)=O,,,,test
US04859684,CCOC(C)(OCC)OCC.Nc1cc(Cn2ccnc2)ccc1NCc1cccnc1>>Cc1nc2cc(Cn3ccnc3)ccc2n1Cc1cccnc1,,CO,,CC(=O)O,,test
US20110053980A1,CN(C)C1CCc2ccc(Br)cc21.Cc1nn(C)c(C)c1B1OC(C)(C)C(C)(C)O1>>Cc1nn(C)c(C)c1-c1ccc2c(c1)C(N(C)C)CC2,,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20130116243A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)N(c3cccnc3)C(=O)CO4)cc2)CCC1>>NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)N(c3cccnc3)C(=O)CO4)cc2)CCC1,,O=C(O)C(F)(F)F,,,,test
US20110245225A1,CC(C)(C)NS(=O)(=O)c1ccccc1.COB(OC)OC>>CC(C)(C)NS(=O)(=O)c1ccccc1B(O)O,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20050176679A1,C#C[C@]1(O)CC[C@H]2[C@H]3[C@H](CC[C@@]21C)C1=C(CC(=O)CC1)C[C@H]3C.OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>C#C[C@]1(O)CC[C@H]2[C@H]3[C@H](CC[C@@]21C)C1=C(CC(=O)CC1)C[C@H]3C.OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO,,CCO,,,,test
US20030105139A1,COc1cc2c(cc1C(F)(F)F)NCC2.Cc1ccncc1-c1cc(NC(=O)Oc2ccccc2)ccc1C>>COc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1ccc(C)c(-c3cnccc3C)c1)CC2,,CN(C)C=O,,,,test
US20130324531A1,COc1cc(C(=O)OCC(=O)N[C@@H](CCC(=O)OCc2ccccc2)C(=O)OCc2ccccc2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F>>COc1cc(C(=O)OCC(=O)N[C@@H](CCC(=O)O)C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F,[Pd],CC(C)O,,,,test
US20040019210A1,CCOc1ccc(F)c(NCc2cnc(SC)nc2NC2CCCC2)c1F.O=C(n1ccnc1)n1ccnc1>>CCOc1ccc(F)c(N2Cc3cnc(SC)nc3N(C3CCCC3)C2=O)c1F,,C1CCOC1,,[H-].[Na+],,test
US06660739B1,CC(C)(C)OC(=O)N1CCC(C(=O)N2CCN(S(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC2)CC1.O=C(O)C(F)(F)F>>O=C(C1CCNCC1)N1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1.O=C(O)C(F)(F)F,,ClCCl,,COc1ccccc1,,test
US05741788,CCOC(=O)N1C2CCC1C(c1nsnc1Cl)=C(Cl)C2>>ClC1=C(c2nsnc2Cl)C2CCC(C1)N2,,Cc1ccccc1,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20090093472A1,Clc1ccc(Cn2cnnc2[C@H]2CCCN2)cc1.O=C=Nc1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc(C(F)(F)F)cc1)N1CCC[C@@H]1c1nncn1Cc1ccc(Cl)cc1,,ClCCl,ClCCl,,,test
US20090042917A1,CCC(C)c1c(Cl)nc(S(C)(=O)=O)nc1C(F)(F)F.c1cn[nH]c1>>CCC(C)c1c(Cl)nc(-n2cccn2)nc1C(F)(F)F,,O,,C1CCOC1,[H-].[Na+],test
US05750213,OB(O)c1cccc(F)c1F.Oc1ccc(Br)cc1>>Oc1ccc(-c2cccc(F)c2F)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Cs+].[Cs+],test
US04225315,CCc1cccc(CC)c1-n1cnc(N)nc1=O.COC(OC)N(C)C>>CCc1cccc(CC)c1-n1cnc(N=CN(C)C)nc1=O,,CC#N,,,,test
US05910498,CCN(CC)CC.CCO.CN(C)C=O.N[C@H]1CCNC1.Nc1cc(-n2cc(C(=O)O)c(=O)c3cc(F)c(Cl)nc32)c(F)cc1F>>CC(C)OC(C)C.Nc1cc(-n2cc(C(=O)O)c(=O)c3cc(F)c(N4CC[C@H](N)C4)nc32)c(F)cc1F,,CCO,,,,test
US20090124666A1,Cc1ncoc1-c1ccc(C(F)(F)F)cn1.ClC(Cl)(Cl)C(Cl)(Cl)Cl>>Cc1nc(Cl)oc1-c1ccc(C(F)(F)F)cn1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20090023720A1,COCCNc1nc2c(Cl)nc3ccccc3c2n1CC(C)(C)O.N>>COCCNc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O,,CO,,,,test
US03966775,Cc1cc2c(cc1C)C(=O)c1c(NO)cccc1C2=O>>Cc1cc2c(cc1C)C(=O)c1c(N)cccc1C2=O,[Zn],O,,CO,Cl,test
US04633025,C=C(C)C(=O)Cl.O=C(O)[C@@H]1CCCN1>>C=C(C)C(=O)N1CCC[C@H]1C(=O)O,,CCOCC,O,[Na+].[OH-],,test
US20120034270A1,COc1ccc(C(=O)O)cc1Cl.N=C(NO)c1ccc2[nH]ccc2c1>>COc1ccc(C(=O)ONC(=N)c2ccc3[nH]ccc3c2)cc1Cl,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20110039889A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c(Cl)nccc34)no2)cc1Cl.CCOC(=O)C1CCNCC1>>CCOC(=O)C1CCN(c2nccc3c(-c4noc(-c5ccc(OC(C)C)c(Cl)c5)n4)cccc23)CC1,,CCCCO,,,,test
US05576335,CCCCCCCN=C=O.Nc1ccc(F)cc1[N+](=O)[O-]>>CCCCCCCNC(=O)Nc1ccc(F)cc1[N+](=O)[O-],CN(C)c1ccncc1,CCOC(C)=O,Cc1ccccc1,,,test
US20020165203A1,COc1ccc(CCNC(=O)CN(CCCN)c2cc(C)nc(-n3ccnc3)n2)cc1.N#C[O-]>>COc1ccc(CCNC(=O)CN(CCCNC(N)=O)c2cc(C)nc(-n3ccnc3)n2)cc1,,c1ccncc1,,O,,test
US06861418B2,CC1(C)OB(c2cccc3[nH]ccc23)OC1(C)C.Fc1cccc(Br)c1>>Fc1cccc(-n2ccc3ccccc32)c1,[Pd],C1CCOC1,CCOC(C)=O,[Na+].[OH-],,test
US20030069424A1,CN1CCNCC1.NC(=O)Cc1cc(Cl)nc2ccccc12>>CN1CCN(c2cc(CC(N)=O)c3ccccc3n2)CC1,,CN1CCCC1=O,,CCOC(C)=O,,test
US20120088767A1,CC(=O)CC(C)=O.Nc1cc(Br)cc([N+](=O)[O-])c1N>>Cc1nc2c([N+](=O)[O-])cc(Br)cc2[nH]1,,CCO,Cl,,,test
US20100261723A1,CS(=O)(=O)Cc1cc(N2CCOCC2)nc(-c2ccc(N)cc2)n1.O=C(O)C1CCC1>>CS(=O)(=O)Cc1cc(N2CCOCC2)nc(-c2ccc(NC(=O)C3CCC3)cc2)n1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150218092A1,C=COC(C)(C)C.O=C(Cl)CCl>>CC(C)(C)OC1CC(=O)C1Cl,,COC(C)(C)C,,CN1CCOCC1,,test
US20060089394A1,CC(C)(C)[Si](C)(C)OCC(O)c1cccc(Br)n1.CCOC(=O)COc1ccc(O)cc1C>>CCOC(=O)COc1ccc(OC(CO[Si](C)(C)C(C)(C)C)c2cccc(Br)n2)cc1C,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150080549A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(I)cc1)C(=O)OCC#N>>N#CCOC(=O)[C@@H](N)Cc1ccc(I)cc1,,CCOCC,,,,test
US20100204208A1,CC1(C)CC(Nc2nc(Cl)ncc2F)CC(C)(C)N1.Nc1cc(C2CC2)cc(-n2cnnn2)c1>>CC1(C)CC(Nc2nc(Nc3cc(C4CC4)cc(-n4cnnn4)c3)ncc2F)CC(C)(C)N1,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20110237588A1,Cc1csc(C(=O)C=CN(C)C)c1.NN>>Cc1csc(-c2cc[nH]n2)c1,,CCO,,O,,test
US20120245178A1,Cc1ccc(N)cn1.OCC(O)CO>>Cc1ccc2ncccc2n1,,O,,O=S(=O)(O)O,[Na+].[OH-],test
US20050203081A1,BrCc1ccccc1.CCOC(C)=O.CN(C)C=O.O=C(O)c1cc(Cl)c(C(=O)O)cc1Cl>>O=C(OCc1ccccc1)c1cc(Cl)c(C(=O)OCc2ccccc2)cc1Cl,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04983601,NN.S=C1Nc2cc(Br)ccc2N2CCc3cccc1c32>>NN=C1Nc2cc(Br)ccc2N2CCc3cccc1c32,,c1ccccc1,,O,,test
US04904680,CC(N)C(C)(C)C.O=C(O)CNC(=O)c1ccccc1>>CC(NC(=O)CNC(=O)c1ccccc1)C(C)(C)C,,CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20160235716A1,C[C@@H](C1CCC1)N(Cc1ccc(F)cc1)S(=O)C(C)(C)C.Cl>>C[C@H](NCc1ccc(F)cc1)C1CCC1.Cl,,C1COCCO1,CO,,,test
US20070027160A1,Fc1c(N2CCC3(CC2)OCCO3)ccc2cccnc12>>O=C1CCN(c2ccc3cccnc3c2F)CC1,,C1CCOC1,,Cl,[Na+].[OH-],test
US04572908,CCOC(=O)CC(=O)COCCN1C(=O)c2ccccc2C1=O.COC(=O)/C=C(/C)N.O=Cc1ccccc1Cl>>CCOC(=O)C1=C(COCCN2C(=O)c3ccccc3C2=O)NC(C)=C(C(=O)OC)C1c1ccccc1Cl,,CC(C)O,,,,test
US05874593,Cc1ccc(-c2ccccc2C#N)cc1.NN.O=N[O-]>>Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,CCO,,Cl,,test
US20070213341A1,C=C(N=Cc1ccccc1C)O[Si](C)(C)C.O=C1Nc2cc(Br)ccc2/C1=C/c1cccc(Cl)c1>>Cc1ccccc1C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Br)ccc12,,Cc1ccccc1,,CO,,test
US04791120,BrCCc1ccccc1.CCC(=O)N(c1ccccc1)C1(c2nnc(CC)o2)CCNCC1>>CCC(=O)N(c1ccccc1)C1(c2nnc(CC)o2)CCN(CCc2ccccc2)CC1,,CC#N,,[I-].[Na+],,test
US20100210623A1,CI.Clc1cncc(Cl)n1>>Cc1ncc(Cl)nc1Cl,,C1CCOC1,,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US20110105502A1,CI.CN(C)C=O.COc1ccc(CC#N)cc1>>COc1ccc(C(C)(C)C#N)cc1,,C1CCOC1,,Cl,,test
US20130059808A1,COC(=O)[C@H]1OC(C)(C)N(C(=O)OC(C)(C)C)[C@@H]1COS(C)(=O)=O.[N-]=[N+]=[N-]>>COC(=O)[C@H]1OC(C)(C)N(C(=O)OC(C)(C)C)[C@@H]1CN=[N+]=[N-],,CN(C)C=O,,O,,test
US05194602,CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@@]3(O)CC[C@]12C>>CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)C3=CC[C@]12C,,O=S(=O)(O)O,,CCOC(C)=O,O,test
US20030055086A1,C=C(C(=O)OCC)C1CCc2cc(Br)ccc21>>C=C(C(=O)O)C1CCc2cc(Br)ccc21,,CC(C)=O,,[Na+].[OH-],,test
US20040132727A1,COc1cc2ncnc(Oc3ccc(NC(=O)COc4ccccc4C)cc3)c2cc1OC>>COc1cc2ncnc(Oc3ccc(NCCOc4ccccc4C)cc3)c2cc1OC,,C1CCOC1,,Cl,[Na+].[OH-],test
US05059611,CCCCCCCCCCC/C(=C\c1coc([Si](C)(C)C)c1)C(=O)OC>>CCCCCCCCCCCC(Cc1coc([Si](C)(C)C)c1)C(=O)OC,[Rh],CCOC(C)=O,,,,test
US20150057270A1,CC(C)(C)OC(=O)Nc1cc(OCc2ccccc2)c2c(Br)cccc2c1.NC(=O)CCC(=O)NI>>CC(C)(C)OC(=O)Nc1cc(OCc2ccccc2)c2c(Br)cccc2c1I,,C1CCOC1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090208485A1,COC1COCCC1(OC)OC>>COC1COCCC1=O,,C1CCOC1,O,Cl,,test
US05432284,CC(C)N(CCC(C#N)(CCN1CCCCC1)c1ccccc1Cl)Cc1ccccc1.O=S(=O)(O)O>>CC(C)N(CCC(CCN1CCCCC1)(C(N)=O)c1ccccc1Cl)Cc1ccccc1,,O,,Cc1ccccc1,,test
US04755511,N#Cc1ccc2c(c1)CCC(CC(=O)O)C2=O.NN>>N#Cc1ccc2c(c1)CCC1CC(=O)NN=C21,,CC(=O)O,,O,,test
US20100280013A1,BrCc1ccccc1.COC(=O)[C@H](C)N>>COC(=O)[C@H](C)NCc1ccccc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20150111885A1,CCS(=O)(=O)c1ccc(OCC2CC2)c(B2OC(C)(C)C(C)(C)O2)c1.Cn1cc(Br)c2c(c1=O)NC(=O)CO2>>CCS(=O)(=O)c1ccc(OCC2CC2)c(-c2cn(C)c(=O)c3c2OCC(=O)N3)c1,,CCCCCC,,CCOC(C)=O,,test
US20140288040A1,CC[C@@H](N[S@](=O)C(C)(C)C)c1ccc(Cl)c(Oc2ccc([N+](=O)[O-])nc2)c1F.Cl>>CC[C@@H](N)c1ccc(Cl)c(Oc2ccc([N+](=O)[O-])nc2)c1F.Cl,,C1COCCO1,Cl,,,test
US20070207999A1,CC[C@H](N)CO.N#Cc1c(N)cccc1F>>CC[C@H](N)COc1cccc(N)c1C#N,,C1COCCO1,,[H-].[Na+],,test
US20060172988A1,CS(=O)(=O)OC1CN(C(c2ccccc2)c2ccccc2)C1.OC1CCNC1>>OC1CCN(C2CN(C(c3ccccc3)c3ccccc3)C2)C1,,CC#N,,CCN(CC)CC,,test
US05302582,CC[C@@H](C)[C@@H](N)C(=O)O.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>CC[C@@H](C)[C@@H](NCC1(O)OC[C@@H](O)[C@@H](O)[C@@H]1O)C(=O)O,,c1ccncc1,,CO,,test
US20020040154A1,O=CCCCC[C@H](O)COc1ccc(F)cc1.O=S(O)c1ccccc1>>O=S(=O)(c1ccccc1)C1CCCC[C@@H](COc2ccc(F)cc2)O1,,ClCCl,,[Ca+2].[Cl-].[Cl-],,test
US20080009541A1,Cl.NC(=O)c1ccc(F)c(F)c1Cl>>Cl.NCc1ccc(F)c(F)c1Cl,,C1CCOC1,,B,,test
US20100010007A1,C[C@H]1[C@@H](c2ccccc2)N(C(=O)C[C@@H](c2cc(F)cc(F)c2)C2CCS(=O)(=O)CC2)C(=O)N1C>>O=S1(=O)CCC([C@@H](CCO)c2cc(F)cc(F)c2)CC1,,C1CCOC1,,[BH4-].[Li+],,test
US20150336892A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.[N-]=[N+]=NCCOCCOCCOCCNS(=O)(=O)c1ccc(OCc2ccccc2)cc1>>CC(C)(C)OC(=O)NCCOCCOCCOCCNS(=O)(=O)c1ccc(O)cc1,[Pd],CO,ClCCl,,,test
US20150148333A1,Cc1noc2c1-c1ccccc1NCC2.O=C(Cl)c1ccccc1>>Cc1noc2c1-c1ccccc1N(C(=O)c1ccccc1)CC2,,C1CCOC1,,CCN(CC)CC,,test
US20160040013A1,C=C(C)C(=O)O.OCCCCO>>C=C(C)C(=O)OCCCCO,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20140309210A1,O=[N+]([O-])c1cn[nH]c1.OCCCBr>>O=[N+]([O-])c1cnn(CCCBr)c1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090239854A1,C=Cc1ccc(C)nc1.Cc1ccc2[nH]c3c(c2c1)CN(c1ccc(O)cc1)CC3>>Cc1ccc2c(c1)c1c(n2CCc2ccc(C)nc2)CCN(c2ccc(O)cc2)C1,,CN1CCCC1=O,,[K+].[OH-],,test
US20160257690A1,Cc1cccc(-c2nc(N)sc2Br)c1>>Cc1cccc(-c2ncsc2Br)c1,,C1CCOC1,CCOC(C)=O,CC(C)(C)ON=O,,test
US05843999,COC(=O)c1c2cccccc-2c(-c2ccccc2)c1-c1ccc(S(C)(=O)=O)cc1>>CS(=O)(=O)c1ccc(-c2c(C(=O)O)c3cccccc-3c2-c2ccccc2)cc1,,CO,,[Na+].[OH-],,test
US20100063101A1,CC(C)(Oc1ccc(-c2nnn[nH]2)cc1)C(C1CCCCC1)n1c(-c2ccc(Cl)cc2)nc2cc(F)c(F)cc21.O>>O=C(O)C(C1CCCCC1)n1c(-c2ccc(Cl)cc2)nc2cc(F)c(F)cc21,,C1COCCO1,O,[Li+].[OH-],,test
US20120264790A1,COC(=O)c1cc(O)c2c(c1)OC(F)(F)O2.Cc1cccc(CCBr)c1>>COC(=O)c1cc(OCCc2cccc(C)c2)c2c(c1)OC(F)(F)O2,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150366197A1,COc1cc(OCc2ccccc2)ccc1Br.COc1cc(OCc2ccccc2)ccc1C(=O)c1c(-n2cccc2C=O)ccn1S(=O)(=O)c1ccc(C)cc1>>COc1cc(OCc2ccccc2)ccc1C(=O)c1c(-n2cccc2C(O)c2ccc(OCc3ccccc3)cc2OC)ccn1S(=O)(=O)c1ccc(C)cc1,,C1CCOC1,,[Li]CCCC,,test
US20090005353A1,CC(C)(C)OC(=O)N1CC(OCC#N)C1>>CC(C)(C)OC(=O)N1CC(OCCN)C1,[Pd],CCO,,,,test
US09187462B2,CC(C)(C)OC(=O)N1CCC[C@H]1[C@@H](NC(=O)OCc1ccccc1)c1ccc(C(F)(F)F)c(F)c1>>CC(C)(C)OC(=O)N1CCC[C@H]1[C@@H](N)c1ccc(C(F)(F)F)c(F)c1,[Pd],CCO,,,,test
US20020006937A1,C1COCCN1.C=O.O=C(NCc1ccc(Cl)cc1)c1cnc2sccc2c1O>>O=C(NCc1ccc(Cl)cc1)c1cnc2sc(CN3CCOCC3)cc2c1O,,CC(=O)O,,CCO,,test
US20030176477A1,N#CC(C=O)c1ccccc1.NNC(=O)c1snc(Cl)c1Cl>>N#CC(=CNNC(=O)c1snc(Cl)c1Cl)c1ccccc1,,CCO,,CC(=O)O,,test
US05948911,Cc1cc2c(Cl)nc(Cl)nc2s1.NCc1ccc2c(c1)OCO2>>Cc1cc2c(NCc3ccc4c(c3)OCO4)nc(Cl)nc2s1,,ClCCl,,CCN(CC)CC,,test
US20070099955A1,CC(CC=O)NC(=O)c1ccc(Cl)cc1.COc1c(C)ccc2c1C[C@@H](C1CCNCC1)O[C@H]2CNC=O>>COc1c(C)ccc2c1C[C@@H](C1CCN(CCC(C)NC(=O)c3ccc(Cl)cc3)CC1)O[C@H]2CNC=O,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05935990,Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1.O=C1CCC(=O)N1Cl>>Cc1c(Cl)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1,,C1CCOC1,,,,test
US20150111870A1,COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1C(=O)O.NC1CC1>>COc1nc2ccc(C(O)(c3ccc(C)nc3C)c3cnnn3C)cc2c(Cl)c1C(=O)NC1CC1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20150152093A1,COc1ccc(CN2C(=O)OC[C@@H]2[C@H](C)F)cc1>>C[C@H](F)[C@H]1COC(=O)N1,,O=C(O)C(F)(F)F,,,,test
US20040204586A1,N#Cc1c(N2CCNCC2)c2cc(F)ccc2n(Cc2ccccc2)c1=O.O=C(Cl)c1ccco1>>N#Cc1c(N2CCN(C(=O)c3ccco3)CC2)c2cc(F)ccc2n(Cc2ccccc2)c1=O,,c1ccncc1,,,,test
US20020040146A1,CCCCOC(=O)N1C[C@H](SCc2ccc(OC)cc2)C[C@H]1CCCn1cccc1>>CCCCOC(=O)N1C[C@H](S)C[C@@H]1CCCn1cccc1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20160002248A1,COC(=O)c1cn(CCCCc2cc3c(I)c(C4CC4)n(S(=O)(=O)c4ccccc4)c3nn2)nn1.C[Zn]C>>COC(=O)c1cn(CCCCc2cc3c(C)c(C4CC4)n(S(=O)(=O)c4ccccc4)c3nn2)nn1,,C1COCCO1,,,,test
US20090069340A1,CCCCC(=O)CC(=O)[O-].NNc1ccccc1>>CCC1=NN(c2ccccc2)C(=O)C1,,CC(=O)O,,,,test
US20100261698A1,CC(=O)c1cccnc1.Cl.NNc1ccc(Br)cc1>>C/C(=N/Nc1ccc(Br)cc1)c1cccnc1.Cl,,CCO,,,,test
US20100075952A1,Cc1c(C=O)[nH]c2c1C(=O)N(C[C@@H](O)CN1CCOCC1)CCC2.O=C1Cc2cc(F)cc(Br)c2N1>>Cc1c(/C=C2\C(=O)Nc3c(Br)cc(F)cc32)[nH]c2c1C(=O)N(C[C@@H](O)CN1CCOCC1)CCC2,,CCO,,C1CCNCC1,,test
US20090181965A1,C1CCNC1.COc1cc(Nc2ncc3c(n2)C(OS(C)(=O)=O)CCC3)ccc1-n1cnc(C)c1>>COc1cc(Nc2ncc3c(n2)C(N2CCCC2)CCC3)ccc1-n1cnc(C)c1,CN(C)C=O,C1CCOC1,,CCN(CC)CC,,test
US20090156642A1,CN(Cc1cc(S(=O)(=O)c2ccccc2)n(-c2cc(F)ccc2F)n1)C(=O)OC(C)(C)C.Cl>>CNCc1cc(S(=O)(=O)c2ccccc2)n(-c2cc(F)ccc2F)n1.Cl,,CCOC(C)=O,,CCO,,test
US06544989B2,Cc1nsc(N)c1Cl.O=C(O)Cc1ccc(O)c([N+](=O)[O-])c1>>Cc1nsc(NC(=O)Cc2ccc(O)c([N+](=O)[O-])c2)c1Cl,,CC(Cl)Cl,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20090054402A1,CCOC(=O)c1[nH]c2c(Br)cccc2c1CCCO.Oc1cccc2ccccc12>>CCOC(=O)c1[nH]c2c(Br)cccc2c1CCCOc1cccc2ccccc12,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040254161A1,NS(=O)(=O)c1cc(Oc2cccc(C(=O)O)c2)ccc1N1CCCC1=O>>O=C(O)c1cccc(Oc2ccc3c(c2)S(=O)(=O)N=C2CCCN23)c1,,C1CCOC1,,C1CCC2=NCCCN2CC1,Cl,test
US20070203127A1,COc1ccc2nccc(N3CCC(O)C3)c2n1.CS(=O)(=O)Cl>>COc1ccc2nccc(N3CCC(OS(C)(=O)=O)C3)c2n1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20160009667A1,CC(C)Oc1ncc(Oc2cc3onc(N)c3cc2Cl)cc1Cl.CS(=O)(=O)Cl>>CC(C)Oc1ncc(Oc2cc3onc(NS(C)(=O)=O)c3cc2Cl)cc1Cl,,ClCCl,,CCN(CC)CC,,test
US20110244481A1,COc1ccc(-c2cnc(N)c(Cc3ccccc3)n2)cc1.COc1ccc(C(C)C(=O)Cl)cc1>>COc1ccc(-c2cnc(NC(=O)C(C)c3ccc(OC)cc3)c(Cc3ccccc3)n2)cc1,CN(C)c1ccncc1,c1ccncc1,,O,,test
US20020052322A1,CCC[C@H](N)C(=O)OC.C[C@H](NC(=O)Cc1cccc([N+](=O)[O-])c1)C(=O)O>>CCC[C@H](NC(=O)[C@H](C)NC(=O)Cc1cccc([N+](=O)[O-])c1)C(=O)OC,,CO,ClC(Cl)Cl,Cl,,test
US20090239845A1,CC=O.Cc1cc(NC(=O)c2ccc3c(c2)CCNC3)nn1Cc1cc(Cl)ccc1OCC(C)C.Cl>>CCN1CCc2cc(C(=O)Nc3cc(C)n(Cc4cc(Cl)ccc4OCC(C)C)n3)ccc2C1.Cl,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04921852,CCOCC.N[C@@H](CO)C(=O)O.O=C(Cl)OCc1ccc([N+](=O)[O-])cc1>>COC(=O)[C@H](CO)NC(=O)OCc1ccc([N+](=O)[O-])cc1,,CCOCC,O,O=C([O-])O.[Na+],,test
US20040053931A1,CC(C)(C)[Si](C)(C)Cl.COc1ccc(C=O)cc1O.NO>>COc1ccc(C#N)cc1O[Si](C)(C)C(C)(C)C,,C1CCOC1,CN(C)C=O,Cl,[H-].[Na+],test
US20160130268A1,CCOC(=O)CC(=O)OCC.O=[N+]([O-])c1ccc(F)c(F)c1>>CCOC(=O)C(C(=O)OCC)c1ccc([N+](=O)[O-])cc1F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150175562A1,CS(=O)(=O)Cl.Nc1nc(CC2CCCCC2)c(Br)s1>>CS(=O)(=O)Nc1nc(CC2CCCCC2)c(Br)s1,,ClCCl,O,,,test
US20160068486A1,O=C(O)[C@@H](O)[C@H](O)C(=O)O>>O=C(O)C(O)C(O)C(=O)O,,Cc1ccccc1C,O,[K+].[OH-],,test
US20090247507A1,CC(C)(C)OC(=O)N1CCNCC1.Nc1ncc(Br)c(Cl)c1[N+](=O)[O-]>>CC(C)(C)OC(=O)N1CCN(c2c(Br)cnc(N)c2[N+](=O)[O-])CC1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20150266900A1,C1COCCN1.NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F>>NS(=O)(=O)c1c(F)c(F)c(N2CCOCC2)c(F)c1F,,CO,,,,test
US20130345252A1,COC(=O)CCCC(=O)Nc1ccc2c3c(n(CCCNC(=O)OC(C)(C)C)c(=O)c2c1)-c1ccccc1C3=O>>COC(=O)CCCC(=O)Nc1ccc2c3c(n(CCCN)c(=O)c2c1)-c1ccccc1C3=O,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US06235771B1,COC(=O)C1=Cc2cc(-c3ccc(C(F)(F)F)cc3)ccc2S(=O)(=O)CC1>>O=C(O)C1=Cc2cc(-c3ccc(C(F)(F)F)cc3)ccc2S(=O)(=O)CC1,,COCCOC,,Cl,,test
US20020156081A1,COc1cc(-c2nn([C@@H]3CC[C@@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1N.O=C(O)c1cc2ccccc2[nH]1>>COc1cc(-c2nn([C@@H]3CC[C@@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2[nH]1,CN(C)C=O,ClCCl,c1ccncc1,O=C(Cl)C(=O)Cl,,test
US05646232,Cc1ccc(C)cc1.O=C(Cl)c1cc(Cl)ccc1Cl>>Cc1ccc(C)c(C(=O)c2cc(Cl)ccc2Cl)c1,,O,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US06432993B1,CN(C(=O)OC(C)(C)C)c1cc(Oc2ccccc2O)ccc1N.O=C(O)COc1ccc(CC2SC(=O)NC2=O)cc1>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccccc2O)ccc1NC(=O)COc1ccc(CC2SC(=O)NC2=O)cc1,,C1CCOC1,,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20160137636A1,COc1cc(C(F)(F)F)ccc1C1c2ccc(SCc3ccccc3)cc2CCN1C(=O)OC(C)(C)C>>COc1cc(C(F)(F)F)ccc1C1NCCc2cc(SCc3ccccc3)ccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060241106A1,BrCc1ccccc1.CCCCCC.CN(C)C=O.COc1ccc(-c2c(C)noc2-c2cc(Br)c(O)cc2O)cc1>>COc1ccc(-c2c(C)noc2-c2cc(Br)c(OCc3ccccc3)cc2OCc2ccccc2)cc1,,CCCCCC,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],test
US06174881B1,NC1=Nc2ccsc2C(c2ccccc2)=NC1.O=C(CCl)CCl>>OCc1cn2c(n1)CN=C(c1ccccc1)c1sccc1-2,,C1COCCO1,,[Na+].[OH-],,test
US20080227834A1,C=CC(=O)O.Cc1cc(Br)ccc1C#N>>Cc1cc(/C=C/C(=O)O)ccc1C#N,,CC#N,CCOC(C)=O,CCN(CC)CC,Cc1ccccc1P(c1ccccc1C)c1ccccc1C,test
US20140018393A1,COC(=O)[C@@H]1CC[C@@H](C=O)CC1.N[C@@H]1C[C@H]1c1ccccc1>>COC(=O)[C@@H]1CC[C@@H](CN[C@@H]2C[C@H]2c2ccccc2)CC1,,CO,,O,[BH3-]C#N.[Na+],test
US20080275029A1,O=c1[nH]cnc2cc(F)ccc12.OCC1(c2ccc(Cl)cc2)CCNCC1>>O=c1[nH]cnc2cc(N3CCC(CO)(c4ccc(Cl)cc4)CC3)ccc12,,CN(C)C=O,,[H-].[Na+],,test
US04680291,CN(C#CCC1=CCCCC1)Cc1cccc2ccccc12>>CN(/C=C\CC1=CCCCC1)Cc1cccc2ccccc12,c1ccncc1,,,[H][H],,test
US20160108047A1,CB1OB(C)OB(C)O1.COc1cc(N2C(=O)c3nc(Br)n(C(C)C)c3C2c2ccc(Cl)cc2)cc2c1nnn2C>>COc1cc(N2C(=O)c3nc(C)n(C(C)C)c3C2c2ccc(Cl)cc2)cc2c1nnn2C,,ClCCl,O,,,test
US04350696,Nc1ccccn1.O=C(O)COc1ccc(Cn2ccnc2)cc1>>O=C(COc1ccc(Cc2ncc[nH]2)cc1)Nc1ccccn1,,C1CCOC1,CN(C)C=O,Cl,O=C(n1ccnc1)n1ccnc1,test
US20060052445A1,O=S(=O)(c1ccc(F)cc1)c1ccc(/C=C/c2ccc(F)cc2)cn1>>O=S(=O)(c1ccc(F)cc1)c1ccc(CCc2ccc(F)cc2)cn1,[Pd],CCOC(C)=O,,CC(=O)O,[H][H],test
US05962469,COc1ccc(CSCc2ccc(CC(C)(C)O)c(CSCc3ccc(OC)cc3)c2O)cc1>>Cc1ccc(CC(C)(C)O)c(C)c1O,,CCO,,,,test
US20100311966A1,C=C(C)COC1CN(C(=O)OC(C)(C)C)CCC1=O.NCc1ccccc1>>C=C(C)CO[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1NCc1ccccc1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20120316161A1,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc2[nH]ccc2c1>>CCCC(C(=O)O)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc2[nH]ccc2c1,,CO,,[Na+].[OH-],,test
US20160024053A1,CC(O)c1cn(-c2ncc(-c3ccccc3F)cn2)c2cc(C(=O)N3CCOCC3)ccc12>>CC(=O)c1cn(-c2ncc(-c3ccccc3F)cn2)c2cc(C(=O)N3CCOCC3)ccc12,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20140364411A1,CN(C)[C@H]1C[C@@H](C(=O)O)N(C)C1.NNc1ccc(F)cn1>>CN(C)[C@H]1C[C@@H](C(=O)NNc2ccc(F)cn2)N(C)C1,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US06107291,COc1ccc(S(=O)(=O)N2CCCCC(COC(C)=O)C2C(=O)O)cc1.NO>>COc1ccc(S(=O)(=O)N2CCCCC(COC(C)=O)C2C(=O)NO)cc1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US04939159,CC(C)n1c(C(Br)Br)c(-c2ccc(F)cc2)c2cccnc21.O>>CC(C)n1c(C=O)c(-c2ccc(F)cc2)c2cccnc21,,CCO,,O=C([O-])[O-].[Ca+2],,test
US06534546B1,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C.O=[N+]([O-])c1cccc(CO)c1>>CC(C)(C)OC(=O)NN(Cc1cccc([N+](=O)[O-])c1)C(=O)OC(C)(C)C,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150210688A1,Cc1c[nH]c(C#N)n1.II>>Cc1nc(C#N)[nH]c1I,,ClCCl,,[Na+].[OH-],,test
US20040092546A1,NCCN1CCOCC1.O=C(c1cc(S(=O)(=O)Cl)c[nH]1)c1cccnc1Cl>>O=C(c1cc(S(=O)(=O)NCCN2CCOCC2)c[nH]1)c1cccnc1Cl,,ClCCl,,CCN(CC)CC,,test
US20160207903A1,C#C[Mg]Br.CCCOc1ccc(C(=O)c2ccc(Br)cc2)cc1>>C#CC(O)(c1ccc(Br)cc1)c1ccc(OCCC)cc1,,C1CCOC1,,,,test
US20030045705A1,Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O.N#C[C@H]1C[C@H](n2ccc(=O)[nH]c2=O)O[C@@H]1COC(c1ccccc1)(c1ccccc1)c1ccccc1>>O=C[C@H]1C[C@H](n2ccc(=O)[nH]c2=O)O[C@@H]1COC(c1ccccc1)(c1ccccc1)c1ccccc1,,C1CCOC1,Cc1ccccc1,CC(C)C[AlH]CC(C)C,,test
US04540705,COC(=O)C1(C)CCCc2ccccc21>>COC(=O)C1(C)CC=Cc2ccccc21,,Cc1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20060069221A1,CCOC(C)=O.COC1(C)CCC(C)=C1Br.C[Si](C)(Cl)Cl.[Li]CCCC>>CC1=CCC(C)=C1[Si](C)(C)C1=CCC=C1,,CCOC(C)=O,,CCOCC,O,test
US20100190754A1,CCCI.COC(=O)c1ncccc1O>>CCCOc1cccnc1C(=O)OC,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20140343029A1,COc1cc(-c2cn(CCN3CCC3)c(C3CCN(c4ncnc(N)c4C#N)CC3)n2)ccc1F.OO>>COc1cc(-c2cn(CCN3CCC3)c(C3CCN(c4ncnc(N)c4C(N)=O)CC3)n2)ccc1F,,CS(C)=O,,[Na+].[OH-],,test
US20120283271A1,CSCC[C@@H](C(=O)Nc1cnc([C@H]2COC(C)(C)O2)cn1)N1Cc2c(cccc2C(F)(F)F)C1=O>>CSCC[C@@H](C(=O)Nc1cnc([C@H](O)CO)cn1)N1Cc2c(cccc2C(F)(F)F)C1=O,,C1CCOC1,,Cl,,test
US20080261978A1,NCc1ccccn1.O=Cc1ccc(S(=O)(=O)N2Cc3ccccc3C2)cc1>>O=S(=O)(c1ccc(CNCc2ccccn2)cc1)N1Cc2ccccc2C1,,CO,,[BH4-].[Na+],,test
US20100069351A1,NC(=O)c1ccccc1O.O=C1CCN(Cc2ccccc2)CC1>>O=C1NC2(CCN(Cc3ccccc3)CC2)Oc2ccccc21,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20120142677A1,CC(C)(C)c1cc(N)no1.C[C@@]1(C(=O)O)CCCN1c1ccc(Cl)cc1>>CC(C)(C)c1cc(NC(=O)[C@]2(C)CCCN2c2ccc(Cl)cc2)no1,,CCOC(C)=O,,C1CCOC1,CCN(CC)CC,test
US20160009744A1,O=C1NC(=O)c2ccccc21.OC(c1cccc(Cl)c1)c1csc(C2OCCO2)c1>>O=C1c2ccccc2C(=O)N1C(c1cccc(Cl)c1)c1csc(C2OCCO2)c1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04025528,CCOC(=O)c1ccc(O)cc1.Clc1nccs1>>CCOC(=O)c1ccc(Oc2nccs2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160145192A1,Cc1cc(O)c(C)c(C)c1O.O=C1CCC(c2ccc(F)cc2)O1>>Cc1c(C)c(O)c(C(CCC(=O)O)c2ccc(F)cc2)c(C)c1O,,Cc1ccccc1,,CCOCC,FB(F)F,test
US04352815,CCOC(=O)c1ncn2c1CN(C)C(=O)c1ccccc1-2.O=[N+]([O-])O>>CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc([N+](=O)[O-])ccc1-2,,O=S(=O)(O)O,,N,,test
US20040127574A1,O=C1NC(Cc2ccc(C(F)(F)F)cc2)C(c2ccc(F)c(F)c2)O1>>NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccc(F)c(F)c1,,CCO,,[Na+].[OH-],,test
US20090029965A1,Cc1nc2c(s1)CCN(C(=O)c1ccc(CN)c(C)c1)c1ccccc1-2.O=C(Cl)C1CC1>>Cc1nc2c(s1)CCN(C(=O)c1ccc(CNC(=O)C3CC3)c(C)c1)c1ccccc1-2,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05466689,CC(C)c1cc(C(C)C)c(S(=O)(=O)Cl)c(C(C)C)c1.CCOC(=O)CCc1c[nH]c2ccccc12>>COC(=O)CCc1cn(S(=O)(=O)c2c(C(C)C)cc(C(C)C)cc2C(C)C)c2ccccc12,,CCCCCC,CN(C)C=O,O,[H-].[Na+],test
US20090176841A1,CCOC(=O)CC(=O)Nc1ccc(C)c2c1cc(C)n2Cc1ccc(O)c(C(O)c2ccc(F)cc2)c1>>Cc1ccc(NC(=O)CC(=O)O)c2cc(C)n(Cc3ccc(O)c(C(O)c4ccc(F)cc4)c3)c12,,C1CCOC1,,Cl,[Na+].[OH-],test
US04026897,CCC(Br)C(=O)Br.O=c1ccc2cccc(O)c2[nH]1>>CCC(Br)C(=O)c1ccc(O)c2[nH]c(=O)ccc12,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20090181963A1,CCn1nnc2c(N3CCOC[C@@H]3C)nc(-c3ccc(N)cc3)nc21.Nc1ccc(CCO)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCn1nnc2c(N3CCOC[C@@H]3C)nc(-c3ccc(NC(=O)Nc4ccc(CCO)cc4)cc3)nc21,,ClCCl,,CCN(CC)CC,,test
US20090203663A1,CC(=O)O.COC(=O)[C@H](Cc1ccc(OC2CCNCC2)cc1)NC(=O)c1c(Cl)cccc1Cl>>CC(=O)N1CCC(Oc2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US03978063,Cl.Cn1nnnc1SCC1=NCCc2cc(OCc3ccccc3)c(OCc3ccccc3)cc21>>Cl.Cn1nnnc1SCC1=NCCc2cc(O)c(O)cc21,,CCO,,,,test
US20080188531A1,O=C(NC(=S)Nc1cnccn1)c1ccccc1>>NC(=S)Nc1cnccn1,,[Na+],[OH-],,,test
US20080161302A1,FC(F)C(F)(F)CI.O=[N+]([O-])c1ccc(O)cc1>>O=[N+]([O-])c1ccc(OCC(F)(F)C(F)F)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05801201,Brc1cccc(OCc2ccccc2)c1.Cc1ccc(CC2CCC(=O)C(CN(C)C)C2)cc1>>Cc1ccc(CC2CCC(O)(c3cccc(OCc4ccccc4)c3)C(CN(C)C)C2)cc1,,CCCCCC,CCOCC,Cl,,test
US04399140,CSc1nc(=O)n(Cc2cccs2)c(C)c1Cl.NN>>Cc1c(Cl)c(NN)nc(=O)n1Cc1cccs1,,CCO,,O,,test
US20130072473A1,CC(=O)Nc1sc2c(c1-c1nnn(C)n1)CCN(C(=O)OC(C)(C)C)C2.O=C(O)C(F)(F)F>>CC(=O)Nc1sc2c(c1-c1nnn(C)n1)CC[NH2+]C2.O=C([O-])C(F)(F)F,,ClCCl,,,,test
US20150376181A1,O=C1NC2(CCCN(Cc3ccccc3)C2)n2c1ccc(Nc1ccncn1)c2=O>>O=C1NC2(CCCNC2)n2c1ccc(Nc1ccncn1)c2=O,,C1COCCO1,Cl,,,test
US20130158041A1,OCC1=CC=CN(c2cccc(Br)c2)N1.Oc1ccc2ncccc2c1>>O=c1ccn(-c2cccc(Br)c2)nc1COc1ccc2ncccc2c1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20010047008A1,CC(=O)Cl.Nc1sc2c(c1C(=O)c1ccco1)CCCC2>>CC(=O)Nc1sc2c(c1C(=O)c1ccco1)CCCC2,,ClCCl,,CCN(CC)CC,,test
US20160176850A1,CCNC(=O)c1cc(N2CCC(COc3cc(-c4nnn(C)c4C)cnc3N)CC2)nc(Cl)n1.COC[C@@H](C)O>>CCNC(=O)c1cc(N2CCC(COc3cc(-c4nnn(C)c4C)cnc3N)CC2)nc(O[C@H](C)COC)n1,,CN(C)C=O,,[H-].[Na+],,test
US20050277647A1,C1CNCCN1.N#Cc1ccc(Cl)c(F)c1>>N#Cc1ccc(N2CCNCC2)c(F)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04407746,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.Nc1cccc(CO)c1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)C(O)c1cccc(N)c1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20070224130A1,CCC1(CC(O)(C=Nc2cccc3cnccc23)C(F)(F)F)CCCc2ccccc21>>CCC1(CC(O)(CNc2cccc3cnccc23)C(F)(F)F)CCCc2ccccc21,,CC(=O)O,,O=C([O-])[O-].[Na+].[Na+],,test
US06200998B1,CCCc1cc(Oc2ccccc2)ccc1O.COC(=O)Cc1ccc(OCCCBr)cc1>>CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc(CC(=O)OC)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050032871A1,CC1(C)OB(c2cccc3[nH]ccc23)OC1(C)C.CCOC(C)=O.Fc1cccc(Br)c1>>O=C1Cc2c(cccc2-c2cccc(F)c2)N1,[Pd],C1CCOC1,CCOC(C)=O,[Na+].[OH-],,test
US20110230476A1,COC(=O)c1ccc2nccc(N3CCN(C(=O)OC(C)(C)C)CC3)c2c1>>CC(C)(C)OC(=O)N1CCN(c2ccnc3ccc(CO)cc23)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120083514A1,CC1(C)NC(=O)NC1=O.N#Cc1ccc(F)cc1C(F)(F)F>>CC1(C)NC(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20020013356A1,O=C1c2ccccc2C2CCCCC12c1c[nH]cn1>>OC1c2ccccc2C2CCCCC12c1c[nH]cn1,,CCO,O,Cl,[Na+].[OH-],test
US20020016365A1,CCOC(=O)C(O)(CC(C)(C)c1cc(F)ccc1OC)C(F)(F)F>>COc1ccc(F)cc1C(C)(C)CC(O)(C(=O)O)C(F)(F)F,,CO,,[K+].[OH-],,test
US20160068531A1,O=C1Nc2cnccc2C12CC2.O=S(=O)(CCCn1c(CCl)cc2cc(Cl)ncc21)C1CC1>>O=C1N(Cc2cc3cc(Cl)ncc3n2CCCS(=O)(=O)C2CC2)c2cnccc2C12CC2,,CN(C)C=O,,[H-].[Na+],,test
US04784474,CC1=Nc2ccccc2C1(C)C.Cc1ccccc1CBr.O=Nc1c(O)ccc2ccccc12>>Cc1ccccc1CN1c2ccccc2C(C)(C)C12C=Nc1c(ccc3ccccc13)O2,,Cc1ccccc1,,C1CCNCC1,,test
US20120136000A1,CC(=O)C(C)C.Ic1cnccn1>>CC(C)C(C)(O)c1cnccn1,,CCOC(C)=O,CCOCC,[Li]CCCC,[Cl-].[NH4+],test
US03989737,C=CCONC(CC)=C1C(=O)CC2CCCCC2C1=O.O=C(Cl)c1ccccc1>>C=CCON=C(CC)C1=C(OC(=O)c2ccccc2)CC2CCCCC2C1=O,,CC(C)=O,O,[Na+].[OH-],,test
US20120230951A1,CC(C)(C)OC(=O)NCC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Clc1cnc2cc(Br)ccc2n1>>CC(C)(C)OC(=O)NCC(=O)c1ccc(-c2cnc3cc(Br)ccc3n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140275011A1,N#CC1(Cn2cnc3ccc(-c4cc(F)ncc4Cl)cc32)CCOCC1.NCCO>>N#CC1(Cn2cnc3ccc(-c4cc(NCCO)ncc4Cl)cc32)CCOCC1,,CCOC(C)=O,CS(C)=O,CCN(C(C)C)C(C)C,,test
US20160211456A1,Brc1cccc(N2c3ccccc3Oc3ccccc32)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(c2cccc(N3c4ccccc4Oc4ccccc43)c2)OC1(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,CC(=O)[O-].[K+],,test
US04585796,CC(CCc1ccc(S(N)(=O)=O)cc1)NC(C)c1ccccc1.O=C(O)C(=O)O>>C[C@H](N)CCc1ccc(S(N)(=O)=O)cc1.O=C(O)C(=O)O,[Ni],CO,,,,test
US20130211075A1,FC(F)(F)c1ccc(Cl)nc1.NN>>Cl.NNc1ccc(C(F)(F)F)cn1,,CCO,,O,,test
US20020045630A1,C#Cc1cccc(N)c1.COCCOCCn1ccc2c(Cl)ncnc21>>C#Cc1cccc(Nc2ncnc3c2ccn3CCOCCOC)c1,,CO,,,,test
US05994342,C=CCCC(=O)O.[N-]=[N+]=NCC1CN2C(=O)CC2O1>>C=CCCC(=O)NCC1CN2C(=O)CC2O1,[Pd],CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20050277652A1,Nc1ccc(Oc2ccnc(NC(=O)N3CCC(N4CCC4)CC3)c2)cc1.O=C=NC(=O)Cc1ccccc1>>O=C(Cc1ccccc1)NC(=O)Nc1ccc(Oc2ccnc(NC(=O)N3CCC(N4CCC4)CC3)c2)cc1,,C1CCOC1,CCCCCC,,,test
US20120046244A1,CC(=O)Nc1ccc(OC(=O)CCl)cc1.CN1CCCC1>>CC(=O)Nc1ccc(OC(=O)C[N+]2(C)CCCC2)cc1.[Cl-],,CCOC(C)=O,,,,test
US20100035942A1,CC1(C)OB(c2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2)OC1(C)C.COCCOC.Cc1ccc(CBr)c(OS(C)(=O)=O)c1.c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>Cc1ccc(Cc2cc(F)c(N3CC(=O)NS3(=O)=O)c(OCc3ccccc3)c2)c(OS(C)(=O)=O)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20070135357A1,CC(=O)OC(C)=O.O=C(O)c1ccc(S)cc1>>CC(=O)Sc1ccc(C(=O)O)cc1,,O,,c1ccncc1,,test
US20110218192A1,CC(=O)c1cc(Br)ccc1O.O=C1CCC(c2ccccc2)CC1>>O=C1CC2(CCC(c3ccccc3)CC2)Oc2ccc(Br)cc21,,CO,,C1CCNC1,,test
US20150361100A1,CCOC(=O)c1cc2ccccn2c1-c1ccc(=O)[nH]n1.ClCCBr>>CCOC(=O)c1cc2ccccn2c1-c1ccc(=O)n(CCCl)n1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20080004297A1,CSc1ccc(N)cc1.Cc1nc(Cl)c2ccccc2n1>>CSc1ccc(Nc2nc(C)nc3ccccc23)cc1,,CCOC(C)=O,,CC(=O)[O-].[Na+],,test
US20120214785A1,NC(=O)Cc1ccc(Cl)nc1>>NCCc1ccc(Cl)nc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140371199A1,N#Cc1ccc(-c2cnc3cnc(-c4ccc(C(=O)N5CCC(=O)CC5)cc4)cn23)cc1>>N#Cc1ccc(-c2cnc3cnc(-c4ccc(C(=O)N5CCC(O)CC5)cc4)cn23)cc1,,CO,,[BH4-].[Na+],,test
US20160002219A1,O=C(C1CC1)N1CC[C@@H](CN2C(=O)C3(CC3)N=C2c2ccc(-c3ccc(O)cc3)cc2)C1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=C(C1CC1)N1CC[C@@H](CN2C(=O)C3(CC3)N=C2c2ccc(-c3ccc(OS(=O)(=O)C(F)(F)F)cc3)cc2)C1,,ClCCl,c1ccncc1,,,test
US20040097548A1,Cc1ccc(C(=O)O[C@@H](C(=O)[O-])[C@@H](OC(=O)c2ccc(C)cc2)C(=O)[O-])cc1.NC1CCCNC1c1ccccc1>>Cc1ccc(C(=O)O[C@@H](C(=O)O)[C@@H](OC(=O)c2ccc(C)cc2)C(=O)O)cc1.N[C@H]1CCCN[C@H]1c1ccccc1,,O,,CCO,,test
US04656269,C1COCCN1.O=C1CC(=Cc2cccc3ccccc23)C(=O)O1>>O=C(O)C(=Cc1cccc2ccccc12)CC(=O)N1CCOCC1,,ClCCl,,,,test
US20120252815A1,CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCNCC4)n3)ccc21.CCOC(=O)C(CCCCl)C(=O)OCC>>CCOC(=O)C(CCCN1CCN(c2nc(-c3ccc4c(c3)C(C)(C)CCC4(C)C)cs2)CC1)C(=O)OCC,,CN1CCCC1=O,,CCN(CC)CC,,test
US20100190831A1,C=C(C)COC(=O)c1c(O)c(CC(=C)C)cc(F)c1F>>CC1(C)Cc2cc(F)c(F)c(C(=O)O)c2O1,,O=CO,,,,test
US20100216758A1,COC(=O)c1ccc(CCn2ccc(OCc3ccc(F)cc3)cc2=O)cc1OC>>COc1cc(CCn2ccc(OCc3ccc(F)cc3)cc2=O)ccc1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05064833,COc1cccc(C(=O)O)c1[N+](=O)[O-]>>COc1cccc(C(=O)O)c1N,[Pd],CCO,,,,test
US20060122185A1,NC(N)=S.O=C(CBr)c1n[nH]c2ncccc12>>Nc1nc(-c2n[nH]c3ncccc23)cs1,,CCO,,Br,,test
US20070149533A1,BrC(Br)(Br)Br.O=[N+]([O-])c1cc(CO)cc(C(F)(F)F)c1>>O=[N+]([O-])c1cc(CBr)cc(C(F)(F)F)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US06528538B1,C=O.CCOC(=O)C1c2ccccc2Oc2ccccc21>>CCOC(=O)C1(CO)c2ccccc2Oc2ccccc21,,C1CCOC1,CN1CCCN(C)C1=O,[Li]CCCC,,test
US04450173,CCOC(=O)CCN.COC(=O)CCc1ccc(OCC2CO2)cc1.Cl>>CCOC(=O)CCNCC(O)COc1ccc(CCC(=O)OC)cc1.Cl,,CC(C)O,,CCN(CC)CC,,test
US20090247507A1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1nccs1>>CC(C)(C)OC(=O)N1CCN(Cc2nccs2)CC1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20050096353A1,CCOC(=O)Cn1ccc2cc(OCc3cnc(-c4ccc(C(F)(F)F)cc4)nc3CCOC)ccc21>>COCCc1nc(-c2ccc(C(F)(F)F)cc2)ncc1COc1ccc2c(ccn2CC(=O)O)c1,,C1CCOC1,,[Li+].[OH-],,test
US20160016908A1,CC(=O)N1c2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)cc2[C@H](Nc2ccccc2)[C@@H](C)[C@@H]1C>>CC(=O)N1c2ccc(N3CCNCC3)cc2[C@H](Nc2ccccc2)[C@@H](C)[C@@H]1C,,CO,,C1COCCO1,Cl,test
US20060135578A1,COc1cc(CO)ccc1OCc1csc(N2CCCCC2)n1.O=Cc1cn(-c2ccccc2)nc1O>>COc1cc(COc2nn(-c3ccccc3)cc2C=O)ccc1OCc1csc(N2CCCCC2)n1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20070254873A1,NC(=O)c1cc(-c2ccccc2)cc2c(C3CCNCC3)c[nH]c12.O=S(=O)(Cl)CCCCl>>NC(=O)c1cc(-c2ccccc2)cc2c(C3CCN(S(=O)(=O)CCCCl)CC3)c[nH]c12,,ClCCl,,CCN(CC)CC,,test
US20050075331A1,CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(NS(=O)(=O)N4CCOC4=O)ccc3N2)c(O)c2cccnc21.NCC(N)=O>>CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(NS(=O)(=O)NCCC(N)=O)ccc3N2)c(O)c2cccnc21,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US04372953,BrCCCSc1nnn[nH]1.Sc1ccccc1>>c1ccc(SCCCSc2nnn[nH]2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120165352A1,C=O.COC(=O)[C@@H]1C[C@@H](O)CN1>>COC(=O)[C@@H]1C[C@@H](O)CN1C,,CO,,[BH3-]C#N.[Na+],,test
US20070213355A1,CN1CCNCC1.N#Cc1cc([N+](=O)[O-])ccc1F>>CN1CCN(c2ccc([N+](=O)[O-])cc2C#N)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060293310A1,CC(C)C[Zn]Br.CNC(=O)COC(=O)N1CCN(c2ccc(Br)nc2)CC1>>CNC(=O)COC(=O)N1CCN(c2ccc(CC(C)C)nc2)CC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,,CCOC(C)=O,O,test
US20120077828A1,Nc1ncc(I)c2scc(-c3ccc4c(c3)CCN4C(=O)Cc3ccccc3)c12.OB(O)c1cccnc1>>Nc1ncc(-c2cccnc2)c2scc(-c3ccc4c(c3)CCN4C(=O)Cc3ccccc3)c12,,CCOC(C)=O,O,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20050131050A1,CC(=O)c1ccc(Cl)cc1.CCOC=O>>O=CCC(=O)c1ccc(Cl)cc1,,CCOCC,,Cl,C[O-].[Na+],test
US04994479,CCCCCCCOc1ccc(CCl)cc1.CCOC(=O)CC1Cc2cc(O)ccc2C1OC>>CCCCCCCOc1ccc(COc2ccc3c(c2)CC(CC(=O)OCC)C3OC)cc1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20140287992A1,C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](OC(=O)c2ccc([N+](=O)[O-])cc2)C[C@H]1C(=O)N[C@]1(C(=O)OCC)CC1C=C.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=CCCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](OC(=O)c2ccc([N+](=O)[O-])cc2)C[C@H]1C(=O)N(C(=O)OC(C)(C)C)[C@]1(C(=O)OCC)CC1C=C,CN(C)c1ccncc1,Cc1ccccc1,,,,test
US20060004197A1,COC(=O)c1cc(NS(=O)(=O)c2ccc(C)cc2)c(NS(=O)(=O)c2ccc(C)cc2)cc1Oc1ccc(OC)cc1>>COc1ccc(Oc2cc(NS(=O)(=O)c3ccc(C)cc3)c(NS(=O)(=O)c3ccc(C)cc3)cc2C(=O)O)cc1,,CCOC(C)=O,CO,[K+].[OH-],,test
US04008326,Cl.O=C(NCc1ccncc1)Nc1cccc2ccccc12>>Cl.O=C(NCc1ccncc1)Nc1cccc2ccccc12,,ClC(Cl)Cl,,,,test
US20130109682A1,CC1OC(c2ccncc2[N+](=O)[O-])=CC(O[Si](C)(C)C(C)(C)C)C1(C)O>>CC1OC(c2ccncc2N)=CC(O[Si](C)(C)C(C)(C)C)C1(C)O,[Fe],CC(=O)O,,,,test
US05026856,CCNc1ccc2c(c1)CNC2.O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O>>CCNc1ccc2c(c1)CN(c1c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c1F)C2,,CN(C)C=O,,,,test
US20130310395A1,CC1(C)OB(c2ccnn2C2CCCCO2)OC1(C)C.COC(=O)c1cnc(N2CC[C@@H](O)C2)c(Br)c1>>COC(=O)c1cnc(N2CC[C@@H](O)C2)c(-c2ccnn2C2CCCCO2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140200206A1,COc1cc(C(=O)NC2COC2)ccc1Nc1nc(OC2(C)CCC2)c2c(-c3ccc4nc(C)oc4c3)cn(COCC[Si](C)(C)C)c2n1>>COc1cc(C(=O)NC2COC2)ccc1Nc1nc(OC2(C)CCC2)c2c(-c3ccc4nc(C)oc4c3)c[nH]c2n1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100130495A1,CO.[BH3-]C#N.c1ncc(-c2ccc(Nc3nc4c(c(NC[C@H]5CCCO5)n3)CNCC4)cc2)o1>>OCCN1CCc2nc(Nc3ccc(-c4cnco4)cc3)nc(NC[C@H]3CCCO3)c2C1,,CO,,CC(=O)O,,test
US05719152,CCOC(=O)C(=O)Cl.COC(=O)CC1CCc2cc(Br)ccc2N1>>CCOC(=O)C(=O)N1C2=CC=C(Br)CC2CCC1CC(=O)OC,,ClCCl,,CCN(CC)CC,Cl,test
US20080132539A1,CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1.N#Cc1ccc(CBr)cc1>>CC(C)(C)OC(=O)NC(Cc1cn(Cc2ccc(C#N)cc2)c2ccccc12)C(=O)OCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20150353580A1,BrP(Br)Br.CN(C)C(=O)C(CCOCCOCCOCCO)C(=O)N(C)C>>CN(C)C(=O)C(CCOCCOCCOCCBr)C(=O)N(C)C,,ClCCl,,O,,test
US20070208007A1,C=O.CCCN(CCC)CCCCNCc1ccc(C(=O)OC)cc1>>CCCN(CCC)CCCCN(C)Cc1ccc(C(=O)OC)cc1,,CCO,,O=CO,,test
US20020026060A1,CCCCCC(C(=O)O)c1ccc2c(c1)C(C)(C)CCC2(C)C.O=C(OCc1ccccc1)c1ccc(O)cc1>>CCCCCC(C(=O)Oc1ccc(C(=O)OCc2ccccc2)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20130137675A1,COc1cn(-c2cccc(C(F)(F)F)c2)ncc1=O>>O=c1cnn(-c2cccc(C(F)(F)F)c2)cc1O,,CC#N,O,C[Si](C)(C)Cl,[I-].[Na+],test
US05389641,CCOC(=O)c1cccc(C)c1[N+](=O)[O-].CCOC(CC)(OCC)N(C)C>>CCOC(=O)c1cccc(CC(=O)CC)c1[N+](=O)[O-],,CCOC(C)=O,,,,test
US20030139418A1,CCOC(=O)c1ccc(CN)cc1.O=Cc1cc(Br)ccc1OCc1ccccc1>>CCOC(=O)c1ccc(CNCc2cc(Br)ccc2OCc2ccccc2)cc1,,CCO,O,CC(=O)O,[BH4-].[Na+],test
US05869584,CC(C)Cc1ccc2c(c1)CC(C)C2=O>>CC1=Cc2ccc(CC(C)C)cc2C1,,C1CCOC1,CO,Cl,[BH4-].[Na+],test
US20050075384A1,O=C(c1ccc([N+](=O)[O-])cc1)n1cc[nH]c1=O>>Nc1ccc(C(=O)n2cc[nH]c2=O)cc1,[Pd],CO,,,,test
US06511997B1,CCC(=O)Nc1n[nH]c(-c2ccc(F)cc2)c1-c1ccncc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCC(=S)Nc1n[nH]c(-c2ccc(F)cc2)c1-c1ccncc1,,CCOC(C)=O,,Cc1ccccc1,Cl,test
US05567717,CCCc1ccc(C=O)o1.COP(=O)(O)C(C)(C)C(=O)[O-]>>CCCc1ccc(C=CC(=O)OC)o1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20050165058A1,COC(=O)c1ccc(I)c(OCCc2ccc(Cl)cc2Cl)c1.N#C[Cu]>>COC(=O)c1ccc(C#N)c(OCCc2ccc(Cl)cc2Cl)c1,,C1COCCO1,,,,test
US20120058985A1,CC(C)(C)OC(=O)N1CC(C(=O)O)C1.Nc1cc(Oc2cc(F)c(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ccn1>>CC(C)(C)OC(=O)N1CC(C(=O)Nc2cc(Oc3cc(F)c(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccn2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060264444A1,COC(=O)c1ccc(OCC(C)=O)cc1.NNc1ccc(F)cc1>>COC(=O)c1ccc(OC/C(C)=N\Nc2ccc(F)cc2)cc1,,CCO,,,,test
US06015826,CN(N=C(Cl)c1c(F)cccc1Cl)S(=O)(=O)c1ccccc1.N#Cc1sc(Cl)c(Cl)c1Cl>>Cn1nc(-c2c(F)cccc2Cl)nc1-c1sc(Cl)c(Cl)c1Cl,,Clc1ccccc1Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120059028A1,CCCI.COC(=O)Cc1c(C)nc2sc3c(c2c1-c1ccccc1Cl)CCCC3>>CCCC(C(=O)OC)c1c(C)nc2sc3c(c2c1-c1ccccc1Cl)CCCC3,,CN(C)C=O,,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US05891889,COC(=O)C1CCN(C(=O)OC(C)(C)C)CC1.Cc1ccccc1CBr>>COC(=O)C1(Cc2ccccc2C)CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US05366972,CCI.CN1C(=O)c2cccnc2Nc2ncccc21>>CCN1c2ncccc2C(=O)N(C)c2cccnc21,,CN(C)C=O,O,[H][H],[H-].[Na+],test
US05250679,C=CCN1CCCc2ccc(OC)cc2C1=O>>C=CCN1CCCc2ccc(O)cc2C1=O,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20030166639A1,CCCN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3cc(C)nc(C)c3)c2)cc1C(F)(F)F>>CCCN(C)c1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3cc(C)nc(C)c3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US04966902,CC(C)(CO)c1ccc(Cl)nn1.CCO>>CCOc1ccc(C(C)(C)CO)nn1,,CS(C)=O,,[H-].[Na+],,test
US20070066820A1,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1.Cl>>Cl.FC(F)(F)c1ccc(Oc2ccc(OC[C@H]3CCCN3)cc2)cc1,,C1COCCO1,,,,test
US05025025,CCOC(=O)CSC(CCCCN=[N+]=[N-])CCCc1cccnc1>>CCOC(=O)CSC(CCCCN)CCCc1cccnc1,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090131413A1,CNCCO.O=C(CCl)Nc1ccc([N+](=O)[O-])cc1>>CN(CCO)CC(=O)Nc1ccc([N+](=O)[O-])cc1,,CCO,,CCOC(C)=O,,test
US20130217666A1,CC(O)(C#Cc1cc2c(cc1F)OCCn1cc(C(N)=O)nc1-2)c1nccn1COCC[Si](C)(C)C>>CC(O)(C#Cc1cc2c(cc1F)OCCn1cc(C(N)=O)nc1-2)c1ncc[nH]1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20060063779A1,CC(=O)N1CCNCC1.CS(=O)(=O)Cc1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)cc1OCCBr>>CC(=O)N1CCN(CCOc2cc(C(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)ccc2CS(C)(=O)=O)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020156081A1,C=O.Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CN(CC2(O)CCNCC2)C1>>CN1CCC(O)(CN2CC(n3nc(-c4ccc(Oc5ccccc5)cc4)c4c(N)ncnc43)C2)CC1,,CC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20080261941A1,CC1(C(=O)NC(=O)Oc2ccccc2)C=CC=CN1.Cc1cccc(C(N)=O)n1.FC(F)(F)c1ccc(Oc2cccc(C=C3CCNCC3)c2)nc1>>Cc1cccc(C(=O)NC(=O)N2CCC(=Cc3cccc(Oc4ccc(C(F)(F)F)cn4)c3)CC2)n1,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20100189773A1,CSc1ncc(C#N)c(Cl)n1.Cc1ccc(S(=O)(=O)n2cc(B3OC(C)(C)C(C)(C)O3)c3cc(C)cnc32)cc1>>CSc1ncc(C#N)c(-c2cn(S(=O)(=O)c3ccc(C)cc3)c3ncc(C)cc23)n1,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20140171348A1,CCCCCCCCCCBr.Cn1ccnc1>>CCCCCCCCCCn1cc[n+](C)c1.[Br-],,Cc1ccccc1,,,,test
US20140235702A1,COc1c(SCC(N)=O)cc(NS(=O)(=O)c2ccc(Br)cc2)c2ccccc12>>NC(=O)CSc1cc(NS(=O)(=O)c2ccc(Br)cc2)c2ccccc2c1O,,ClCCl,,CC#N,O,test
US20080009482A1,CCOC(=O)C1(CN(c2nc(Cl)ncc2[N+](=O)[O-])C(C)C)CC1>>CC(C)N1CC2(CC2)C(=O)Nc2cnc(Cl)nc21,[Fe],CC(=O)O,,,,test
US20150231281A1,Br.CC(=O)OC[C@H]1O[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O>>CC(=O)OC[C@H]1OC(O)(Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O,,CC(=O)O,ClCCl,,,test
US04721718,Nc1ccccn1.O=CCCl>>c1ccn2ccnc2c1,,CO,N,,,test
US20080275043A1,O=C(O[C@@H]1CC[C@H](N2CCC(Cc3ccc(Cl)cc3Cl)C2=O)CC1)c1ccc([N+](=O)[O-])cc1>>O=C1C(Cc2ccc(Cl)cc2Cl)CCN1[C@@H]1CC[C@H](O)CC1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20070093483A1,COC(=O)c1cccc(CC#N)c1>>N#CCc1cccc(C(=O)O)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20110092501A1,COCCCc1ccc(C=O)cc1.C[Si](C)(C)C#N.Nc1ccc2nc[nH]c2c1.O=C(n1ccnc1)n1ccnc1>>COCCCc1ccc(C2CNC(=O)N2c2ccc3[nH]cnc3c2)cc1,[Pd],,,CCN(CC)CC,,test
US20130150407A1,COC(=O)Cc1cc2ccc(F)cc2c(C2CCNCC2)c1C.O=S(=O)(Cl)C1CCCC1>>COC(=O)Cc1cc2ccc(F)cc2c(C2CCN(S(=O)(=O)C3CCCC3)CC2)c1C,,ClCCl,O,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20140275030A1,Cc1noc(C)c1-c1cc(C=O)c2[nH]c(=O)n3c2c1OC[C@@H]3c1ccccn1>>Cc1noc(C)c1-c1cc(CO)c2[nH]c(=O)n3c2c1OCC3c1ccccn1,,CCO,,[BH4-].[Na+],,test
US20130109789A1,COCC(CO)(CO)C1CCCCC1.O=C1CCCCC1>>COCC1(C2CCCCC2)COC2(CCCCC2)OC1,,C1CCOC1,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US05728724,Br[Mg]c1cccs1.COc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(N(C)C)sc2c1>>COc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(-c3cccs3)sc2c1,,C1CCOC1,,,,test
US20160024110A1,CCOC(=O)C(=O)c1ccc(F)cc1.ClC(Cl)(Cl)Cl>>CCOC(=O)C(=C(Cl)Cl)c1ccc(F)cc1,,ClCCl,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05416119,CCN(CC)CCS(=O)(=O)CC(Cc1ccccc1)C(=O)OCc1ccccc1>>CCN(CC)CCS(=O)(=O)CC(Cc1ccccc1)C(=O)O,[Pd],CCO,,,,test
US20060100229A1,COCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)O>>COCCn1nc2c(N)nc3c(c2c1CC(C)(C)O)CCCC3,O=[Pt]=O,O=C(O)C(F)(F)F,,,,test
US20130266645A1,COc1ccc2c(c1)CC[C@H]1[C@@H]3C[C@@H](N=[N+]=[N-])[C@@H](O)[C@@]3(C)CC[C@H]21>>COc1ccc2c(c1)CC[C@H]1[C@@H]3C[C@@H](N)[C@@H](O)[C@@]3(C)CC[C@H]21,[Ni],CO,,NN,O,test
US06265434B1,COc1ccc(COC(=O)[C@@H](C2CCCCC2)N2C[C@H](c3ccccc3)[C@@H](C=O)C2)cc1.c1cc(CCCN2CCCCC2)n2nnnc2c1>>O=C(O)[C@@H](C1CCCCC1)N1C[C@H](c2ccccc2)[C@@H](CN2CCC(CCCc3cccc4nnnn34)CC2)C1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090069340A1,CC#N.Cc1ccc(Cl)cc1N1CCNCC1.Cn1c(CBr)c(Cl)c(=O)n1-c1ccc(Cl)cc1>>CCn1c(CN2CCN(c3cc(Cl)ccc3C)CC2)c(Cl)c(=O)n1-c1ccc(Cl)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070270383A1,CC(C)c1nc(CN(C)C(=O)N[C@H](C(=O)N[C@@H](Cc2ccccc2)C[C@H](O)[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)C(C)C)cs1.CSC>>CSCO[C@@H](C[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)N(C)Cc1csc(C(C)C)n1)C(C)C)[C@H](Cc1ccccc1)NC(=O)OCc1cncs1,,CC#N,CCOC(C)=O,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US05506219,CC(C)c1c(C=C(Br)Br)c(-c2ccc(F)cc2)nc2ccccc12>>C#Cc1c(-c2ccc(F)cc2)nc2ccccc2c1C(C)C,,C1CCOC1,,[Li]CCCC,,test
US04845118,COc1ccc(COC(=O)Oc2ccccc2)cc1.Cc1ccc(CSc2nc3cscc3[nH]2)nc1>>COc1ccc(COC(=O)n2c(SCc3ccc(C)cn3)nc3cscc32)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04647301,O=C(O)c1cc2cc(OC(F)F)ccc2nc1C(=O)O>>O=C1OC(=O)c2nc3ccc(OC(F)F)cc3cc21,,CC(=O)OC(C)=O,,,,test
US20100022638A1,Cc1ccc(S(=O)(=O)Cl)cc1.O[C@@H]1CO[C@@H]2[C@@H](O)CO[C@H]12>>Cc1ccc(S(=O)(=O)O[C@H]2CO[C@@H]3[C@H](O)CO[C@H]23)cc1,,Cc1ccccc1,O,[K+].[OH-],,test
US20100075968A1,CN1CC(C(=O)OC(C)(C)C)N(CC(F)(F)F)C1=O>>CN1CC(C(=O)O)N(CC(F)(F)F)C1=O,,ClCCl,O=C(O)C(F)(F)F,,,test
US04001419,CN1CCC2(CC1)c1ccccc1Oc1ccccc12.O=C(Cl)Oc1ccccc1>>O=C(Oc1ccccc1)N1CCC2(CC1)c1ccccc1Oc1ccccc12,,ClCCl,,,,test
US20040122001A1,CC(C)(C)[Si](C)(C)OCCNC(=O)c1ccc2c(c1)CCCN2CC=O.Fc1ccc2c(C3=CCNCC3)c[nH]c2c1>>O=C(NCCO)c1ccc2c(c1)CCCN2CCN1CC=C(c2c[nH]c3cc(F)ccc23)CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US04137315,CCOc1ncc2c(=O)c3ccc([N+](=O)[O-])n3c3cccc1c23.NCCNCCO>>O=c1c2cnc(NCCNCCO)c3cccc(c32)n2c([N+](=O)[O-])ccc12,,CN(C)C=O,,,,test
US20060229294A1,COC(=O)CCSc1ncccc1C#N>>N#Cc1ccc[nH]c1=S,,C1CCOC1,,[H-].[Na+],,test
US20090137580A1,C#Cc1cccc(N)c1.Cn1ccc2ncnc(Oc3ccc(N)c(Cl)c3)c21.O=C(Cl)Oc1ccccc1>>C#Cc1cccc(NC(=O)Nc2ccc(Oc3ncnc4ccn(C)c34)cc2Cl)c1,,CN1CCCC1=O,,c1ccncc1,,test
US20070135463A1,CCOC(=O)N1CCC(Oc2cc3c(Nc4ccc(F)c(Cl)c4)ncnc3cc2OC)CC1>>COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OC1CCNCC1,,CC(C)O,,[K+].[OH-],,test
US20130217666A1,CCOC(=O)c1nc2c([nH]1)C1CC(C1)c1cc(F)c(I)cc1-2.N>>NC(=O)c1nc2c([nH]1)C1CC(C1)c1cc(F)c(I)cc1-2,,CO,,,,test
US20080146523A1,Cl.c1ccc(CNc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)cc1>>Cl.c1ccc(CNc2c[nH]cn2)cc1,,C1COCCO1,,,,test
US20150225403A1,C1CCNC1.COCCc1nc2c(C#CCCCCCl)n[nH]c2c(=O)[nH]1>>COCCc1nc2c(CCCCCCN3CCCC3)n[nH]c2c(=O)[nH]1,[Pd],CCO,CN(C)C=O,CCN(CC)CC,[H][H],test
US05106869,CCCCC(F)C(=O)OC.COP(C)(=O)OC>>CCCCC(F)C(=O)CP(=O)(OC)OC,,C1CCOC1,,[Li]CCCC,,test
US20100184815A1,CC(C)(C)c1ccc(CBr)cc1.CCCCCCCn1c(COC(c2ccccc2)(c2ccccc2)c2ccccc2)n[nH]c1=O>>CCCCCCCn1c(CO)nn(Cc2ccc(C(C)(C)C)cc2)c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140088075A1,CCn1c(=O)c(-c2cc(NC(=O)Oc3ccccc3)c(F)cc2F)cc2cnc(NC(=O)CC#N)cc21.Nc1ccccc1>>CCn1c(=O)c(-c2cc(NC(=O)Nc3ccccc3)c(F)cc2F)cc2cnc(NC(=O)CC#N)cc21,,CS(C)=O,,,,test
US04382892,CC1COc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23.OC1CCNCC1>>CC1COc2c(N3CCC(O)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23,,CS(C)=O,,,,test
US20070167443A1,Cc1ccc(C(=O)c2c[nH]c3ccccc3c2=O)nc1C.Fc1ccccc1CBr>>Cc1ccc(C(=O)c2cn(Cc3ccccc3F)c3ccccc3c2=O)nc1C,,CN(C)C=O,,[H-].[Na+],,test
US20160016951A1,CC(C)n1cc(B2OC(C)(C)C(C)(C)O2)cn1.Clc1ccc(I)cc1>>CC(C)n1cc(-c2ccc(Cl)cc2)cn1,,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US05684034,CCc1c(CC(N)=O)c2cc(OCCCP(=O)(OC)OC)ccc2n1Cc1ccccc1>>CCc1c(CC(N)=O)c2cc(OCCCP(=O)(O)OC)ccc2n1Cc1ccccc1,,CO,O,[Na+].[OH-],,test
US20060211720A1,CCC(=O)c1cccc(Br)c1>>CCCc1cccc(Br)c1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20050277630A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)OCCC(C(=O)c2ccccc2)C3=O)C(=O)O1.O=Cc1ccncc1>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)OCCC(=Cc2ccncc2)C3=O)C(=O)O1,,CC(=O)O,,C1CCNCC1,,test
US20060178514A1,CCN(CC1CCCC1)c1nc2c(cc1C=O)c(C)nn2C.NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CCN(CC1CCCC1)c1nc2c(cc1CNCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c(C)nn2C,CC(=O)O,CO,,[BH3-]C#N.[Na+],,test
US05192781,CCCc1nc(NCC(=O)OC)sc1Cc1ccc([N+](=O)[O-])cc1>>CCCc1nc(NCC(=O)OC)sc1Cc1ccc(N)cc1,[Ni],CO,,,,test
US04593102,C1CCOC1.CCN(CC)CCCN.O=C(n1ccnc1)n1ccnc1.O=S(=O)(c1ccccc1)C1CCNC1>>CCN(CC)CCCNC(=O)N1CCC(S(=O)(=O)c2ccccc2)C1.O,,C1CCOC1,,,,test
US04173633,COc1ccc2c(c1)CCC1CCNC(=O)C(CC(C)=NC(C)C)=C21>>COc1ccc2c(c1)CCC1CCNC(=O)C(CC(C)NC(C)C)=C21,O=[Pt]=O,CCO,,,,test
US20060030737A1,CC(O)c1ccccc1C(C)O.CN(C)P(c1ccccc1)N(C)C>>CC1OP(c2ccccc2)OC(C)c2ccccc21,,Cc1ccccc1,,,,test
US08273341B2,O=C(COC(=O)C1CC2(CC2)CN1C(=O)OCc1ccccc1)c1ccc2c(c1)oc1cc(Br)ccc12>>O=C(OCc1ccccc1)N1CCC2(CC2)C1,,Cc1ccccc1C,,C,O=C[O-].[NH4+],test
US20070032522A1,CC(C)(C)OC(=O)N1CCNCC1.CCOC(=O)c1cn(Cc2ccc(Cl)cc2)c2cc(F)c(F)cc2c1=O>>CCOC(=O)c1cn(Cc2ccc(Cl)cc2)c2cc(N3CCN(C(=O)OC(C)(C)C)CC3)c(F)cc2c1=O,,CC#N,,,,test
US04368253,COCOC.O=Cc1ccc(O)cc1>>COCOc1ccc(C=O)cc1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20020183513A1,O=C(CCCCCCCBr)NOCc1ccccc1.Oc1cccc2[nH]c3ccccc3c12>>O=C(CCCCCCCOc1cccc2[nH]c3ccccc3c12)NOCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060241127A1,Cc1n[nH]c2cccc(Oc3ccc(N)cc3F)c12.Nc1nc(Cl)cc(-c2ccncc2)n1>>Cc1n[nH]c2cccc(Oc3ccc(Nc4cc(-c5ccncc5)nc(N)n4)cc3F)c12,,O,,Cl,,test
US20110245272A1,Cc1ccc(S(=O)(=O)OCCc2ccc(C)nc2)cc1.c1cnc2[nH]c3c(c2c1)C1CCCN1CC3>>Cc1ccc(CCn2c3c(c4cccnc42)C2CCCN2CC3)cn1,,CN(C)C=O,O,[H-].[Na+],,test
US20050192287A1,CC(C)(C)OC(=O)N1CCC(CC(=O)O)CC1.CC(C)c1cccc(Nc2nc3cc(Oc4ccnc(N)c4)ccc3n2C)c1>>CC(C)c1cccc(Nc2nc3cc(Oc4ccnc(NC(=O)CC5CCN(C(=O)OC(C)(C)C)CC5)c4)ccc3n2C)c1,CN(C)c1ccncc1,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20050245741A1,CN.COC(=O)c1ccccc1O>>CNC(=O)c1ccccc1O,,CO,,,,test
US08188133B2,Nc1ccc(Oc2ccc(-c3c[nH]c(COc4ccccc4)n3)cc2)cc1F.S=C(Cl)Cl>>Fc1cc(Oc2ccc(-c3c[nH]c(COc4ccccc4)n3)cc2)ccc1N=C=S,,C1CCOC1,CCOCC,CCN(CC)CC,O,test
US20100197926A1,CNC(=O)c1ccc(C)c([N+](=O)[O-])c1.COC(OC)N(C)C>>CNC(=O)c1ccc(C=CN(C)C)c([N+](=O)[O-])c1,,CN(C)C=O,,,,test
US04602014,CCOC(=O)c1cnc2c(c1Cl)CC(c1ccccc1)CC2.NNc1ccc(Cl)cc1>>O=c1c2c[nH]c3c(c-2nn1-c1ccc(Cl)cc1)CC(c1ccccc1)CC3,,CCCCO,,,,test
US20100056639A1,Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1N.Nc1c(F)c(F)cc(C(=O)O)c1F>>Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1cc(F)c(F)c(N)c1F,,ClCCl,,O=S(Cl)Cl,c1ccncc1,test
US06858591B2,CCOC(=O)[C@@H](N)[C@@H](O)[C@H]1O[C@@H](OC)[C@@H]2OC(C)(C)O[C@@H]21.O=C(OCc1ccccc1)ON1C(=O)CCC1=O>>CCOC(=O)[C@H](NC(=O)OCc1ccccc1)[C@@H](O)[C@H]1O[C@@H](OC)[C@@H]2OC(C)(C)O[C@@H]21,,CCOC(C)=O,ClCCl,CCN(CC)CC,CN(C)c1ccccn1,test
US20090233903A1,CC[Si](Cl)(CC)CC.O=S(=O)(C1CC1)N1CC(O)C1>>CC[Si](CC)(CC)OC1CN(S(=O)(=O)C2CC2)C1,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20070149562A1,Cl.N#CC1CCC(N[C@H](Cc2ccc(Cl)cc2)C(=O)N2CCC(Cn3cncn3)(C3CCCCC3)CC2)CC1>>Cl.N#CC1CCC(N[C@H](Cc2ccc(Cl)cc2)C(=O)N2CCC(Cn3cncn3)(C3CCCCC3)CC2)CC1,,CCOCC,ClCCl,,,test
US20120190665A1,COc1ccc(Cl)cc1-c1nn(C(C)C(=O)O)cc1NC(=O)c1n[nH]c2cncnc12.NC1COC1>>COc1ccc(Cl)cc1-c1nn(C(C)C(=O)NC2COC2)cc1NC(=O)c1n[nH]c2cncnc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20050101643A1,CC[C@H](CI)Cc1ccc(F)cc1F.COC(=O)N1CCC(=O)N(C)[C@@H]1C(C)(C)C>>CCC(Cc1ccc(F)cc1F)CC1CN(C(=O)OC)C(C(C)(C)C)N(C)C1=O,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20100234344A1,COC(=O)c1cncc(Cl)c1CO.ClC(Cl)(Cl)Cl>>COC(=O)c1cncc(Cl)c1CCl,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04835157,CI.O=C(c1ccc(F)cc1)C1CCN(CCn2c(=O)[nH]c3cscc3c2=O)CC1>>Cn1c(=O)n(CCN2CCC(C(=O)c3ccc(F)cc3)CC2)c(=O)c2cscc21,,CN(C)C=O,,O,[H-].[Na+],test
US20150031727A1,CCC(CC)N(Cc1cccc(-c2nc3sc4c(c3c(=O)o2)CCCC4)c1)C(=O)CCC(C)(C)C(=O)O.CI>>CCC(CC)N(Cc1cccc(-c2nc3sc4c(c3c(=O)o2)CCCC4)c1)C(=O)CCC(C)(C)C(=O)OC,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20110218189A1,CC(C)(C)n1c(-c2c(Cl)cccc2Cl)cc2cnc(Cl)nc21>>Clc1ncc2cc(-c3c(Cl)cccc3Cl)[nH]c2n1,,O=S(=O)(O)O,,,,test
US20100069629A1,CCI.COc1ccc(CN(Cc2ccc(OC)cc2)c2ncc(-c3nc(N4CCOCC4)nc4c3CCN4)cn2)cc1>>CCN1CCc2c(-c3cnc(N(Cc4ccc(OC)cc4)Cc4ccc(OC)cc4)nc3)nc(N3CCOCC3)nc21,,CN(C)C=O,O,[H-].[Na+],,test
US20070232632A1,COCC(=O)N=S(C)(=O)c1ccc(N)cc1>>COCCN=S(C)(=O)c1ccc(N)cc1,,C1CCOC1,,,,test
US04386031,COC(=O)CCCCCCCNc1cccc(C(F)(F)F)c1.COc1cc(C(=O)Cl)cc(OC)c1OC>>COC(=O)CCCCCCCN(C(=O)c1cc(OC)c(OC)c(OC)c1)c1cccc(C(F)(F)F)c1,,CCOCC,,CCN(CC)CC,,test
US20070087287A1,CC(C(=O)F)(C(F)(F)F)C(F)(F)F.OCCN1CCOCC1>>CC(C(=O)OCCN1CCOCC1)(C(F)(F)F)C(F)(F)F,,CC#N,,CCN(CC)CC,,test
US20130317024A1,COC(=O)c1ccn(C(C)C)c1.O=C1CCC(=O)N1Br>>COC(=O)c1cc(Br)n(C(C)C)c1,,ClC(Cl)(Cl)Cl,,,,test
US20070270588A1,CCC(CC)Nc1nc(N(CC)c2c(C)cc(C)cc2C)nc(C)c1C(=O)C(=O)N(CC)CC>>CCC(CC)N1C(=O)C(=O)c2c(C)nc(N(CC)c3c(C)cc(C)cc3C)nc21,,CC(C)O,,Cl,,test
US20140045819A1,COC(CNCc1ccccc1F)OC.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(CN(Cc1ccccc1F)S(=O)(=O)c1ccc(C)cc1)OC,,ClCCl,,c1ccncc1,,test
US20060079536A1,CCOC(=O)CC(=N)N.O=CCCl>>CCOC(=O)c1cc[nH]c1N,,CCOC(C)=O,,,,test
US20120252778A1,CCc1nn2c(C)cc(C)nc2c1Cc1ccc(O)cc1.COC(=O)CBr>>CCc1nn2c(C)cc(C)nc2c1Cc1ccc(OCC(=O)OC)cc1,,C1CCOC1,,[H-].[Na+],,test
US04064266,CC(C)(C)c1cc(C=O)cc(I)c1O.N#CCC#N>>CC(C)(C)c1cc(C=C(C#N)C#N)cc(I)c1O,,O,c1ccccc1,C1CCNCC1,CC(=O)O,test
US20070155721A1,CCOC(=O)c1oc2cc(F)ccc2c1C(=O)OCC>>CCOC(=O)c1coc2cc(F)ccc12,,CS(C)=O,,O,[Cl-].[Na+],test
US20110053916A1,CC1(C)OB(c2ccc(CC#N)cc2)OC1(C)C.Clc1nccc(Nc2cc(C3CC3)[nH]n2)n1>>N#CCc1ccc(-c2nccc(Nc3cc(C4CC4)[nH]n3)n2)cc1,,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20080161346A1,COc1cc2nccc(CN3CCc4c(C(=O)Cl)cccc4C3=O)c2cc1OC.Nc1ccc(F)c(C(F)(F)F)c1>>COc1cc2nccc(CN3CCc4c(C(=O)Nc5ccc(F)c(C(F)(F)F)c5)cccc4C3=O)c2cc1OC,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05441949,C=CCOC(=O)c1cc([N+](=O)[O-])c2ncccc2c1>>C=CCOC(=O)c1cc(N)c2ncccc2c1,,CO,,Cl[Sn]Cl,,test
US20040186151A1,CCCCn1cc(-c2ccc(Cl)cc2Cl)nc1[C@H](Cc1ccc(OCc2ccc(C(=O)OC)cc2)cc1)NC(=O)OC(C)(C)C.Cl>>CCCCn1cc(-c2ccc(Cl)cc2Cl)nc1[C@@H](N)Cc1ccc(OCc2ccc(C(=O)OC)cc2)cc1.Cl,,C1COCCO1,,,,test
US20120094971A1,NCCCCCC(=O)Nc1ccccc1[N+](=O)[O-]>>NCCCCCC(=O)Nc1ccccc1N,[Pd],CO,,,,test
US20150336949A1,C[C@H]1CO1.Cc1ccc(S(=O)(=O)n2cc(-c3cnn(CCc4ccccc4)c3)c3cc(-c4ccc(N5CCNCC5)nc4)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3cnn(CCc4ccccc4)c3)c3cc(-c4ccc(N5CCN(C[C@H](C)O)CC5)nc4)cnc32)cc1,,CCO,,CCN(C(C)C)C(C)C,,test
US04710510,CC1(C)C(=O)Nc2cc(N)c(N)cc21.O=Cc1ccc(-n2ccnc2)cc1>>CC1(C)C(=O)Nc2cc3[nH]c(-c4ccc(-n5ccnc5)cc4)nc3cc21,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080045537A1,CN1CCN(c2c(Cl)ccc(N)c2[N+](=O)[O-])CC1>>CN1CCN(c2c(Cl)ccc(N)c2N)CC1,Cl[Ni]Cl,CCO,,[BH4-].[Na+],,test
US20100267699A1,CC(C)(C)OC(=O)N1CCN(CCCOc2ccc(C3CCNCC3)cc2)CC1.FC(F)(F)c1nnc2ccc(Cl)nn12>>CC(C)(C)OC(=O)N1CCN(CCCOc2ccc(C3CCN(c4ccc5nnc(C(F)(F)F)n5n4)CC3)cc2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20140066424A1,CCOC(=O)c1nc(-c2ccc(OC(F)(F)F)cc2)no1.NN>>NNC(=O)c1nc(-c2ccc(OC(F)(F)F)cc2)no1,,CCO,,O,,test
US06211234B1,C=CC(=O)OC.O=C(Cc1ccccc1)c1cccc(OCc2ccccc2)c1>>COC(=O)CCC(C(=O)c1cccc(OCc2ccccc2)c1)c1ccccc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20120001161A1,CC(C)(C)c1cc2ccc3c(Br)cc(Br)c4ccc(c1)c2c34.Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1.OB(O)c1ccc(Cl)cc1>>CC(C)(C)c1cc2ccc3c(-c4ccc(Cl)cc4)cc(-c4ccc(Cl)cc4)c4ccc(c1)c2c34,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20120264749A1,COC(=O)c1ccc(S(=O)(=O)CCCCl)cc1>>O=C(O)c1ccc(S(=O)(=O)C2CC2)cc1,,CC(C)(C)O,O,CC(C)(C)[O-].[K+],,test
US05229379,CCCCP(=O)(CCCNCc1ccc(Cl)cc1)OCC.Cl>>CCCCP(=O)(O)CCCNCc1ccc(Cl)cc1.Cl,,Cl,,,,test
US20050203091A1,CC(=O)OC(C)=O.Cc1cnc(Oc2ccc(F)cc2F)cc1N>>CC(=O)Nc1cc(Oc2ccc(F)cc2F)ncc1C,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20100168039A1,COc1ccc(CS[C@H]2C(=O)N(c3ccc(Cl)cc3)[C@@H]2c2ccc(OCC(=O)OC(C)(C)C)cc2)cc1.O=[N+]([O-])c1cccnc1SCl>>CC(C)(C)OC(=O)COc1ccc([C@@H]2[C@@H](SSc3ncccc3[N+](=O)[O-])C(=O)N2c2ccc(Cl)cc2)cc1,,ClCCl,,,,test
US20070244092A1,CCC(C)(C)c1nc2cc(S(=O)(=O)Cl)ccc2n1CC1CCOCC1.O=C(NC1CC1)c1cc[nH]c1>>CCC(C)(C)c1nc2cc(S(=O)(=O)n3ccc(C(=O)NC4CC4)c3)ccc2n1CC1CCOCC1,,C1CCOC1,,[H-].[Na+],,test
US20080119518A1,C=CCc1c(O)cccc1C(=O)OCC.CI>>C=CCc1c(OC)cccc1C(=O)OCC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05053509,COn1cc(C(=O)O)c(=O)c2cc3cc(F)c(F)cc3nc21.c1ccc(C2CNCCN2)cc1>>COn1cc(C(=O)O)c(=O)c2cc3cc(F)c(N4CCNC(c5ccccc5)C4)cc3nc21,,CS(C)=O,,CC(=O)O,O,test
US20100016337A1,Brc1ccc(Br)nn1.CC(C)(C)OC(=O)CO>>CC(C)(C)OC(=O)COc1ccc(Br)nn1,,CN(C)C=O,,[H-].[Na+],,test
US04804773,CC[Si](CC)(CC)OC1(C(F)(F)F)c2ccccc2C(=O)c2ccccc21>>CC[Si](CC)(CC)OC1(C(F)(F)F)c2ccccc2C(O)c2ccccc21,[Zn],CCO,,CC(=O)O,O,test
US20030232875A1,COC(=O)c1cc2scc(Cl)c2[nH]1>>O=C(O)c1cc2scc(Cl)c2[nH]1,,CO,,[Li+].[OH-],,test
US20060122383A1,C(=NC1CCCCC1)=NC1CCCCC1.CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.CN(C)c1ccccn1.ClCCl>>Cc1ccc(CCOC(=O)[C@@H](NC(=O)OCc2ccccc2)C(C)C)cc1,,ClCCl,,,,test
US06441017B1,CC(C)(C)OC(=O)N(CCc1cncn1Cc1ccc(C#N)c(F)c1)[C@H]1CCN(c2cccc3ccc(O[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)cc23)C1=O>>CC(C)(C)OC(=O)N(CCc1cncn1Cc1ccc(C#N)c(F)c1)[C@H]1CCN(c2cccc3ccc(O)cc23)C1=O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US08334292B1,CO.ClCc1nc(Cl)nc(Cl)c1Br>>COCc1nc(Cl)nc(Cl)c1Br,,CO,,C[O-].[Na+],,test
US20160172678A1,C=COC(C)=O.C=CSCC>>C=COC(C)=O.C=CSCC,,CO,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20140235566A1,CC(C)OC(=O)OCI.CCOC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(NO)nc2=O)[C@](C)(O)[C@@H]1O)Oc1ccccc1>>CCOC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@@H](n2ccc(NOCOC(=O)OC(C)C)nc2=O)[C@](C)(O)[C@@H]1O)Oc1ccccc1,,CN(C)C=O,,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],test
US20020065246A1,COC(=O)C(Cc1ccc(O[Si](C)(C)C(C)(C)C)cc1)OCc1ccc(C(=O)OC(C)(C)C)cc1>>COC(=O)C(Cc1ccc(O)cc1)OCc1ccc(C(=O)OC(C)(C)C)cc1,,C1CCOC1,,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US06274584B1,CN(CCc1ccccc1NS(=O)(=O)c1ccccc1)C(=O)[C@@H](Cc1ccc2ccccc2c1)N(C)C(=O)OC(C)(C)C>>CN[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)CCc1ccccc1NS(=O)(=O)c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20030092770A1,CC(O)(CN)c1ccc(I)cc1.CCCS(=O)(=O)Cl>>CC(C)S(=O)(=O)NCC(C)(O)c1ccc(I)cc1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20130137672A1,CC(C)(C)OC(=O)N1CCC2CNC2C1.O=C(Cl)c1ccccc1-c1ccccc1>>CC(C)(C)OC(=O)N1CCC2CN(C(=O)c3ccccc3-c3ccccc3)C2C1,,ClCCl,,CCN(CC)CC,,test
US20140155415A1,CSc1ccccc1C(NS(=O)C(C)(C)C)c1cc2ccccc2s1>>CSc1ccccc1C(N)c1cc2ccccc2s1,,CCOCC,,Cl,,test
US20030125334A1,C1CNCCN1.CC(C)(C)OC(=O)N(Cc1cccc(F)c1)c1cncc(Cl)n1>>CC(C)(C)OC(=O)N(Cc1cccc(F)c1)c1cncc(N2CCNCC2)n1,,CCO,,,,test
US20140194431A1,CC(C)N1CCn2c(Cc3ccccc3-c3ccc(F)c(F)c3)nc(=O)c(OCc3ccccc3)c2C1=O>>CC(C)N1CCn2c(Cc3ccccc3-c3ccc(F)c(F)c3)nc(=O)c(O)c2C1=O,[Pd],CO,,,,test
US20130237515A1,COc1ccc(COc2cnn(C3CCCCO3)c(=O)c2)nc1>>COc1ccc(COc2cn[nH]c(=O)c2)nc1,,CO,,Cl,,test
US04977146,CC(=O)CCl.CCCOc1c(O)cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CC(C)=O>>CCCOc1c(OCC(C)=O)cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CC(C)=O,,CCOCC,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20110207698A1,CNCCO.N#Cc1c(N)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1cnc(I)s1>>CN(CCO)c1ncc(-c2c(C#N)c(N)nc(SCc3csc(-c4ccc(Cl)cc4)n3)c2C#N)s1,,CC(C)=O,,,,test
US20100016279A1,FC(F)(F)c1nnc2ccc(Cl)nn12.c1ccc(CN2CC3CNCC3C2)cc1>>FC(F)(F)c1nnc2ccc(N3CC4CN(Cc5ccccc5)CC4C3)nn12,,CCO,,CCN(C(C)C)C(C)C,Cl,test
US20030149043A1,CC(C)(C)OC(=O)NC(=N)N.CC(C)c1c(C(=O)O)cnn1-c1ccc2ncccc2c1>>CC(C)c1c(C(=O)NC(=N)NC(=O)OC(C)(C)C)cnn1-c1ccc2ncccc2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20150038528A1,CCCCOC(=O)c1nc(Br)c2cc(Oc3ccc(C)cc3)ccc2c1O.N#C[Cu]>>CCCCOC(=O)c1nc(C#N)c2cc(Oc3ccc(C)cc3)ccc2c1O,,CN(C)C=O,,ClCCl,,test
US05441971,COCOC(C)c1ccc(CCO)nc1.O=[N+]([O-])c1ccc(F)cc1>>COCOC(C)c1ccc(CCOc2ccc([N+](=O)[O-])cc2)nc1,,CN(C)C=O,,O,[H-].[Na+],test
US20090280106A1,CC(C)(C)S.N#Cc1cncc(Br)c1>>CC(C)(C)Sc1cncc(C#N)c1,,CN(C)C=O,,[H-].[Na+],,test
US20040229900A1,COC(=O)c1cc(C#N)ccc1O.NC1CC1>>N#Cc1ccc(O)c(C(=O)NC2CC2)c1,,CS(C)=O,O,,,test
US20160122307A1,CC(=O)O.CC(C)(C)[Si](C)(C)O[C@@H]1CCCc2nccnc21>>CC(=O)O.CC(C)(C)[Si](C)(C)O[C@@H]1CCC[C@@H]2NCCN[C@@H]21,O=[Pt]=O,CC(=O)O,,CO,[H][H],test
US05958375,O=C(Nc1cc(C(=O)NCC(O)CO)cc([N+](=O)[O-])c1)Nc1cc(C(=O)NCC(O)CO)cc([N+](=O)[O-])c1>>Nc1cc(NC(=O)Nc2cc(N)cc(C(=O)NCC(O)CO)c2)cc(C(=O)NCC(O)CO)c1,[Pd],CO,O,Cl,,test
US20080176308A1,NCCCNc1c2c(nc3cc(Cl)ccc13)CCCC2.O=C1CCc2[nH]c(=O)ccc2C1>>O=c1ccc2c([nH]1)CCC(NCCCNc1c3c(nc4cc(Cl)ccc14)CCCC3)C2,,CC(=O)O,ClCCl,O=C([O-])O.[Na+],,test
US20150368240A1,C#C[Si](C)(C)C.O=C(c1ccc(Br)cn1)N1CCc2nc(NC3Cc4ccccc4C3)ncc2C1>>C[Si](C)(C)C#Cc1ccc(C(=O)N2CCc3nc(NC4Cc5ccccc5C4)ncc3C2)nc1,[Cu]I,CN(C)C=O,,CCN(CC)CC,,test
US20090203697A1,COC(=O)/C=C/[C@H]1CC[C@@H](c2ccc(F)c(F)c2)N1C(=O)OC(C)(C)C>>COC(=O)/C=C/[C@@H]1CC[C@H](c2ccc(F)c(F)c2)N1,,CCOC(C)=O,Cl,,,test
US20130231327A1,COC(=O)c1ccc2c(c1)[C@H](N)CC2.O=S(=O)(Cl)c1ccccc1Cl>>COC(=O)c1ccc2c(c1)[C@H](NS(=O)(=O)c1ccccc1Cl)CC2,,CCOC(C)=O,ClCCl,CCN(CC)CC,Cl,test
US06521643B1,COc1ccnc(-c2ccc(F)cc2)c1.O=[N+]([O-])O>>COc1ccnc(-c2ccc(F)c([N+](=O)[O-])c2)c1,,O=S(=O)(O)O,,[Na+].[OH-],,test
US05123954,CC=CCNc1ccc(Cl)c(C(C)C)c1.O=C(Cl)C(Cl)c1cccc(F)c1>>CC=CCN(C(=O)C(Cl)c1cccc(F)c1)c1ccc(Cl)c(C(C)C)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050272763A1,CN(C(=O)C(F)(F)F)c1c(C(=O)C(C)(C)C)oc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc12>>CNc1c(C(=O)C(C)(C)C)oc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc12,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US04874775,CS(=O)(=O)Cl.c1cncc(CNc2ccc(OCC3CCCCC3)cc2)c1>>CS(=O)(=O)N(Cc1cccnc1)c1ccc(OCC2CCCCC2)cc1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20110257402A1,CC(C)(C(=O)Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.CCn1ncc2c(Cl)c(NC)cnc21>>CCn1ncc2c(Cl)c(N(C)C(=O)C(C)(C)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cnc21,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04433150,BrCCc1ccccc1.c1ccc(-c2cc(CCC3CCNCC3)c3ccccc3n2)cc1>>c1ccc(CCN2CCC(CCc3cc(-c4ccccc4)nc4ccccc34)CC2)cc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20150112058A1,CN(Cc1cc([N+](=O)[O-])ccc1Br)C(=O)OCc1ccccc1>>CN(Cc1cc(N)ccc1Br)C(=O)OCc1ccccc1,[Zn],CO,,[Cl-].[NH4+],,test
US20120157439A1,CCCS(=O)(=O)Nc1ccc(Cl)c(NC(=O)c2csc3c(Cl)ncnc23)c1Cl>>CCCS(=O)(=O)Nc1ccc(Cl)c(NC(=O)c2csc3cncnc23)c1Cl,[Zn],CC(=O)O,,,,test
US20050049257A1,CCc1nc(-c2ccc(Cl)cc2Cl)c(CC)nc1N[C@@H]1c2ccccc2C[C@@H]1O.CCc1nc(NC2c3ccsc3CCC2C)c(CC)nc1Br>>CCc1nc(-c2ccc(Cl)cc2Cl)c(CC)nc1N[C@@H]1c2ccsc2CC[C@H]1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,,,test
US20090099160A1,CC(C)(C)OC(=O)N1CCCC(N)C1.O=C(Cl)c1ccc(I)cc1>>CC(C)(C)OC(=O)N1CCCC(NC(=O)c2ccc(I)cc2)C1,,C1CCOC1,,CCN(CC)CC,,test
US20020147203A1,COC(=O)c1cccc(N)n1>>Nc1cccc(CO)n1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110053940A1,Cc1c(Br)cc(CN(C(=O)OC(C)(C)C)C2CC2)cc1C=O.Fc1cccc([Mg]Br)c1>>Cc1c(Br)cc(CN(C(=O)OC(C)(C)C)C2CC2)cc1C(O)c1cccc(F)c1,,C1CCOC1,,,,test
US05385897,O=C(O)c1cccnc1.O=S(Cl)Cl>>Cl.O=C(Cl)c1cccnc1,,Cc1ccccc1,,,,test
US07122683B2,CC(C)(C)OC(=O)N1CC[C@H](N)C1.CC1(C(=O)O)CC1>>CC(C)(C)OC(=O)N1CC[C@H](NC(=O)C2(C)CC2)C1,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US20050026916A1,CSC1=N[C@@H](c2ccccc2)[C@@H](c2ccccc2)N1C(=O)OC(C)(C)C.NCc1cc(F)c(F)c(F)c1>>CC(C)(C)OC(=O)N1C(NCc2cc(F)c(F)c(F)c2)=N[C@@H](c2ccccc2)[C@H]1c1ccccc1,,CO,,,,test
US20070073060A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H]1CO1.NC1CCOCC1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNC1CCOCC1,,CCO,,,,test
US06066641,N#CCC(=O)NC(=O)NCc1cccc(Cl)c1>>Nc1cc(=O)[nH]c(=O)n1Cc1cccc(Cl)c1,,CC(C)O,,[K+].[OH-],,test
US20090270402A1,CC(C)(C)OC(=O)N1CCN(C(N)=S)CC1.CC(C)c1nnc2ccc(C(Br)C(=O)c3ccc(F)cc3F)nn12>>CC(C)c1nnc2ccc(-c3sc(N4CCNCC4)nc3-c3ccc(F)cc3F)nn12,,CCO,,,,test
US06121283,NCc1ccccc1.O=C(O)Cc1cc([N+](=O)[O-])ccc1C(=O)O>>O=C1Cc2cc([N+](=O)[O-])ccc2C(=O)N1Cc1ccccc1,,CC(=O)O,,O,,test
US20100029782A1,CCOC(=O)CCc1ccc(Cl)c([C@H](O)COS(=O)(=O)c2ccc(C)cc2)c1>>CCOC(=O)CCc1ccc(Cl)c([C@H]2CO2)c1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20050049260A1,BrCC1CC1.Oc1cccc(-c2nn3c(NC4CCCC4)cccc3c2-c2ccnc(NC3CCCC3)n2)c1>>c1cc(OCC2CC2)cc(-c2nn3c(NC4CCCC4)cccc3c2-c2ccnc(NC3CCCC3)n2)c1,,CC#N,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US05721234,CC(=O)OC(C)=O.NC1CCc2c([N+](=O)[O-])cc3[nH]c(=O)c(=O)[nH]c3c2C1>>CC(=O)NC1CCc2c([N+](=O)[O-])cc3[nH]c(=O)c(=O)[nH]c3c2C1,,CN(C)C=O,,CCN(CC)CC,,test
US20050154201A1,CC(C)=NOc1cc(CN2[C@H](c3ncccc3C)CCC[C@@H]2c2ncccc2C)ccc1C#N>>Cc1cccnc1[C@@H]1CCC[C@H](c2ncccc2C)N1Cc1ccc2c(N)noc2c1,,CCO,,Cl,,test
US20130018049A1,CCOC(=O)C=C(N)N.COC(=O)C(=Cc1ccc2c(c1)CCCO2)C(C)=O>>CCOC(=O)C1=C(N)NC(C)=C(C(=O)OC)C1c1ccc2c(c1)CCCO2,,CC(C)O,,CN1CCOCC1,Cl,test
US20060004017A1,COc1cc2c(Oc3ccc4[nH]cc(C)c4c3)ncnc2cc1OC[C@H]1CO1.NCCCN1CCCC1>>COc1cc2c(Oc3ccc4[nH]cc(C)c4c3)ncnc2cc1OC[C@H](O)CNCCCN1CCCC1,,CN(C)C=O,,,,test
US04920219,COC(=O)c1cc(Cl)c2c(ccn2C(C)=O)c1OC>>COC(=O)c1cc(Cl)c2c(c1OC)CCN2C(C)=O,[Pt],CO,,CC(=O)O,,test
US04647558,CSC1(N)CN([Si](C)(C)C(C)(C)C)C1=O.O=C(Cl)C(C(=O)OCc1ccc([N+](=O)[O-])cc1)c1ccsc1>>CSC1(NC(=O)C(C(=O)OCc2ccc([N+](=O)[O-])cc2)c2ccsc2)CN([Si](C)(C)C(C)(C)C)C1=O,,ClCCl,,CCN(CC)CC,Cc1ccc(S(=O)(=O)O)cc1,test
US20140057909A1,CC(C)N(NC(=O)c1cccc(O)c1)C(=O)/C=C/c1cn(C(=O)OC(C)(C)C)c2ccccc12.COCCBr>>COCCOc1cccc(C(=O)NN(C(=O)/C=C/c2cn(C(=O)OC(C)(C)C)c3ccccc23)C(C)C)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06723722B1,CC1CN(C(=O)OC(C)(C)C)CC(=O)N1.NOP(=O)(c1ccccc1)c1ccccc1>>CC1CN(C(=O)OC(C)(C)C)CC(=O)N1N,,CN(C)C=O,,[H-].[Na+],,test
US04086219,COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12.O=C(N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O)OCc1ccccc1>>COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)OCc1ccccc1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20150203489A1,C1COCCN1.COCc1cn(Cc2cnc3c(N4CCOCC4)nc(Cl)nc3c2)nn1>>Clc1nc(N2CCOCC2)c2ncc(CN3CCOCC3)cc2n1,,C1CCOC1,C1CCOC1,CCN(CC)CC,O=C([O-])O.[Na+],test
US20090239854A1,C=Cc1ccc(C(F)(F)F)nc1.Cc1ccc2[nH]c3c(c2c1)CN(C)C1(CC1)C3>>Cc1ccc2c(c1)c1c(n2CCc2ccc(C(F)(F)F)nc2)CC2(CC2)N(C)C1,,CN1CCCC1=O,,[K+].[OH-],,test
US20110065702A1,O=C1Cc2cc(OC(F)(F)F)ccc2N1.O=Cc1ccc2[nH]nnc2c1>>O=C1Nc2ccc(OC(F)(F)F)cc2/C1=C\c1ccc2[nH]nnc2c1,,CO,,C1CCNCC1,,test
US20120083502A1,Cc1ccccc1-c1c(COS(C)(=O)=O)nc2cccc(C)n2c1=O.Sc1ncnc2[nH]cnc12>>Cc1ccccc1-c1c(CSc2ncnc3[nH]cnc23)nc2cccc(C)n2c1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040116697A1,CC(=O)OC(C)=O.CSc1nc(Nc2ccccc2F)c(C=O)c(-c2ccccc2F)n1>>CSc1nc(-c2ccccc2F)c2ccc(=O)n(-c3ccccc3F)c2n1,,c1ccncc1,,,,test
US20150158847A1,COc1ccc(COc2ccc(CNc3ncc(I)cc3[N+](=O)[O-])cc2OC)cn1>>COc1ccc(COc2ccc(CNc3ncc(I)cc3N)cc2OC)cn1,[Fe],CC(=O)O,CCOC(C)=O,,,test
US20130065925A1,COc1ccc(COC(=O)C2(CC(=O)OC(C)(C)C)CN(Cc3ccccc3)CC2C)cc1.O=C(Cl)OCc1ccccc1>>COc1ccc(COC(=O)C2(CC(=O)OC(C)(C)C)CN(C(=O)OCc3ccccc3)CC2C)cc1,,ClCCl,,,,test
US20160032047A1,CC(=O)OC(C)=O.COc1cc(/C=C/C(=O)O)ccc1O>>COc1cc(/C=C(\C(C)=O)C(=O)O)ccc1O,,O,,Cl,c1ccncc1,test
US20090048230A1,CC(Cl)OC(=O)N1CCC(CNC(=O)OC(C)(C)C)(c2ccccc2)CC1>>CC(C)(C)OC(=O)NCC1(c2ccccc2)CCNCC1,,CO,,,,test
US20160046614A1,CCOC(=O)c1cccc(SCc2ccc(OC)cc2)c1F>>CCOC(=O)c1cccc(S)c1F,,O=C(O)C(F)(F)F,,,,test
US04733002,CCCCCC(=O)C=Cc1ccc(OC)c(OC)c1>>CCCCCC(=O)C=Cc1ccc(O)c(O)c1,,ClCCl,,BrB(Br)Br,,test
US04748246,C1CC2(CCN1)OCCO2.Clc1cnccn1>>O=C1CCN(c2cnccn2)CC1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US06602825B1,C=CCOC(=O)C(C)Br.Cn1c(=S)n(C)c(=O)n(-c2cc(O)c(Cl)cc2F)c1=O>>C=CCOC(=O)C(C)Oc1cc(N2C(=O)N(C)CN(C)C2=O)c(F)cc1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100113796A1,CCI.CCOC(=O)CCn1cc(Cl)c2cc(-c3noc(-c4ccc(O)c(Cl)c4)n3)ccc21>>CCOC(=O)CCn1cc(Cl)c2cc(-c3noc(-c4ccc(OCC)c(Cl)c4)n3)ccc21,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US04650872,CC(=O)Cl.N#Cc1cc(Cl)nc(NN)c1>>CC(=O)NNc1cc(C#N)cc(Cl)n1,,c1ccncc1,,O,,test
US05736487,CC(=O)Nc1ccc(OCc2nc3ccccc3s2)cc1.CCOC(=O)Cl>>CCOC(=O)N(C(C)=O)c1ccc(OCc2nc3ccccc3s2)cc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US04800212,CC1(C)Cc2ccc(C#N)cc2[C@@H](N)[C@@H]1O.O=C(Cl)CCCCl>>CC1(C)Cc2ccc(C#N)cc2[C@@H](N2CCCC2=O)[C@@H]1O,,ClCCl,,CCN(CC)CC,Cl,test
US20130029961A1,CC1CCN(c2nc(C(F)(F)F)ccc2CN)CC1.CN(C)c1ncc(NC(=O)Oc2ccccc2)cc1C(F)(F)F>>CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cnc(N(C)C)c(C(F)(F)F)c2)CC1,,CS(C)=O,O,CCN(CC)CC,,test
US20040029928A1,CCOC(C)=O.COc1ccc(S(=O)(=O)Cl)cc1.Nc1cccc(/C(=C\C(=O)[O-])c2ccccc2)c1>>CCOC(=O)/C=C(/c1ccccc1)c1cccc(NS(=O)(=O)c2ccc(OC)cc2)c1,,c1ccncc1,,Cl,,test
US20110311474A1,CC[C@@H]1C[C@H](NS(=O)(=O)C2CC2)C[C@@H]1NCCCc1cnc2c(ccn2S(=O)(=O)c2ccc(C)cc2)c1Cl>>CC[C@@H]1C[C@H](NS(=O)(=O)C2CC2)C[C@@H]1N1CCCc2cnc3c(ccn3S(=O)(=O)c3ccc(C)cc3)c21,,CCCO,,CCN(C(C)C)C(C)C,[I-].[K+],test
US20050009829A1,COC(=O)c1nc2cccnc2n1Cc1cc(-c2ccc(Cl)s2)on1>>O=C(O)c1nc2cccnc2n1Cc1cc(-c2ccc(Cl)s2)on1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20070129408A1,C[C@@H](O)c1cc(-c2cccc(Cl)c2)on1.Cn1c(-c2cccnc2)nnc1S(C)(=O)=O>>C[C@@H](Oc1nnc(-c2cccnc2)n1C)c1cc(-c2cccc(Cl)c2)on1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20080293771A1,CI.Cc1nc2ccccc2n1-c1ccc(C(=O)N[C@@H]2CCN(C(=O)OC(C)(C)C)C2)cc1>>Cc1nc2ccccc2n1-c1ccc(C(=O)N(C)[C@@H]2CCN(C(=O)OC(C)(C)C)C2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20050165063A1,CCCN(CCC)CCCCOCc1ccc(CNCc2ncc[nH]2)cc1.O=Cc1ncc[nH]1>>CCCN(CCC)CCCCOCc1ccc(CN(Cc2ncc[nH]2)Cc2ncc[nH]2)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20150225397A1,Cc1nc(Nc2cccnc2)c2c(n1)[C@@]1(c3ccccc3)CC(C#N)C(=O)[C@@H](C)[C@@H]1CC2>>Cc1nc(Nc2cccnc2)c2c(n1)[C@@]1(c3ccccc3)C=C(C#N)C(=O)[C@@H](C)[C@@H]1CC2,,C1COCCO1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20040043998A1,CSc1nc2ccnn2c(Cl)c1C#N.NCc1ccncc1>>CSc1nc2ccnn2c(NCc2ccncc2)c1C#N,,O,,CC#N,CCN(CC)CC,test
US20040058965A1,COC(=O)Cc1ccccc1O.Cc1oc(-c2ccccc2)nc1CCOc1ccc(CCl)cc1>>COC(=O)Cc1ccccc1OCc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1,,O,,CN(C)C=O,[H-].[Na+],test
US20060014663A1,BrC1CCC=CCCC1.CC=O>>CC(=O)C1CCC=CCCC1,,CCOCC,,Cl,[Mg],test
US20040204407A1,C1CCNC1.CC(C(=O)O)c1c[nH]c2c1C(=O)CCC2>>O=C1CCCc2[nH]cc(CCC(=O)N3CCCC3)c21,,ClCCl,,O,O=C(n1ccnc1)n1ccnc1,test
US20090269301A1,CCOC(=O)C(=O)CC(=O)C1CC1.Nc1ccc2[nH]cnc2c1.O=Cc1ccc2nonc2c1>>O=C(C1=C(O)C(=O)N(c2ccc3[nH]cnc3c2)C1c1ccc2nonc2c1)C1CC1,,CCO,,,,test
US20040147543A1,C=CS(C)(=O)=O.CCOCc1nc2cnc3cc(Br)ccc3c2n1CC(C)(C)O>>CCOCc1nc2cnc3cc(Br)ccc3c2n1CC(C)(C)OCCS(C)(=O)=O,,C1CCOC1,,O,[H-].[Na+],test
US20120205632A1,Clc1cnc2c3ccccc3c3ccccc3c2n1.OB(O)c1cccc(-c2cccc3c2sc2ccccc23)c1>>c1cc(-c2cnc3c4ccccc4c4ccccc4c3n2)cc(-c2cccc3c2sc2ccccc23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20160237090A1,CS(=O)(=O)Cl.C[C@H]1Cn2ncc(N3CC(CN)CC3=O)c2CN1C(=O)OC(C)(C)C>>C[C@H]1Cn2ncc(N3CC(CNS(C)(=O)=O)CC3=O)c2CN1C(=O)OC(C)(C)C,,ClCCl,,,,test
US20140051679A1,CN1CCC(Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.O=C(N[C@H](c1ccccn1)C1CC1)c1ccc2[nH]nc(I)c2c1>>CN1CCC(Oc2ccc(-c3n[nH]c4ccc(C(=O)N[C@H](c5ccccn5)C5CC5)cc34)cc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US06017919,CCCCCCc1cc(-c2cccc(C=CC(=O)OC)c2)ccc1OC>>CCCCCCc1cc(-c2cccc(C=CC(=O)O)c2)ccc1OC,,CCO,,[Na+].[OH-],,test
US20080255114A1,COC(=O)c1cccc2oc(N3[C@@H](C)CN(C(=O)N4CCCC4)C[C@@H]3C)nc12>>C[C@H]1CN(C(=O)N2CCCC2)C[C@H](C)N1c1nc2c(C(=O)O)cccc2o1,,c1ccncc1,,[I-].[Li+],,test
US20100120785A1,CCI.CCOC(=O)Cc1c(CC)n[nH]c1CC>>CCOC(=O)Cc1c(CC)nn(CC)c1CC,,C1CCOC1,,[H-].[Na+],,test
US04033975,ClCl.Nc1ccccn1.[Br-]>>Nc1ncc(Cl)cc1Br,,O,,Cl,,test
US20080255086A1,CC(C)(C)c1n[nH]cc1C=O.CNC(=O)c1c(NC(=O)CBr)sc2c1CCCC2>>CNC(=O)c1c(NC(=O)Cn2cc(C=O)c(C(C)(C)C)n2)sc2c1CCCC2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140206663A1,C=C(c1cc2c(cc1NC1CN(C(=O)OC(C)(C)C)C1)N1C(=NNC(=O)C1C)CO2)C(F)(F)F>>CC1C(=O)NN=C2COc3cc(C(C)C(F)(F)F)c(NC4CN(C(=O)OC(C)(C)C)C4)cc3N21,[Pd],CCOC(C)=O,,,,test
US07071175B1,CCOC(=O)c1ccnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1>>CC(C)(C)OC(=O)Nc1cc(CO)ccn1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100048636A1,CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)c2cccc(F)c2F)C1>>CC(C)(C)OC(=O)N1CCC[C@@H](C(O)c2cccc(F)c2F)C1,,CO,,[BH4-].[Na+],,test
US20160122364A1,Brc1cnc2c(Br)snc2c1.NCc1ccccc1>>Brc1cnc2c(NCc3ccccc3)snc2c1,,CCO,,,,test
US20140031364A1,COc1cccc(N2CCNCC2)c1.Cc1onc(-c2ccccc2C(F)(F)F)c1C(=O)O>>COc1cccc(N2CCN(C(=O)c3c(-c4ccccc4C(F)(F)F)noc3C)CC2)c1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20100120844A1,CC(C)(C)OC(=O)NCc1c(F)cccc1CC=Cc1ccccc1>>NCc1c(F)cccc1CC=Cc1ccccc1,,CCOC(C)=O,Cl,O=C([O-])O.[Na+],,test
US20040162285A1,CCOC(=O)CC1=NS(=O)(=O)c2c(ccc(O)c2[N+](=O)[O-])N1>>CCOC(=O)CC1=NS(=O)(=O)c2c(ccc(O)c2N)N1,[Pd],CO,,[H][H],,test
US20120264737A1,COCCc1nnc(-c2cc(C(=O)OC)c(C)cc2C(C)C)[nH]1>>COCCc1nnc(-c2cc(C(=O)O)c(C)cc2C(C)C)[nH]1,,O,,CO,[Li+].[OH-],test
US20140005213A1,COC(=O)[C@H](COC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C>>C=C(NC(=O)OC(C)(C)C)C(=O)OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US03939159,COc1ccc(-n2cccc2)c(N)c1.O=C1CCN(Cc2ccccc2)CC1>>COc1ccc2c(c1)NC1(CCN(Cc3ccccc3)CC1)c1cccn1-2,,CCO,,CC(=O)O,,test
US20110152285A1,O=[N+]([O-])c1cccc(F)c1C=CN1CCCC1>>Fc1cccc2[nH]ccc12,[Ni],CO,,,,test
US03998834,COC(=O)C1(Nc2ccccc2)CCN(Cc2ccccc2)CC1>>COC(=O)C1(Nc2ccccc2)CCNCC1,[Pd],CO,,[H][H],,test
US20130149244A1,CC(C)(C)OC(=O)N=C(N)N(Cc1ccc(OCCCO)c(Br)c1)C(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N=C(N)N(Cc1ccc(OCCCOS(C)(=O)=O)c(Br)c1)C(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20090233903A1,C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C4(CC#N)CC(COS(C)(=O)=O)(COS(C)(=O)=O)C4)c3)ncnc21>>CC1(C)CC(CC#N)(n2cc(-c3ncnc4c3ccn4COCC[Si](C)(C)C)cn2)C1,,CN(C)C=O,,[BH4-].[Na+],,test
US20050222410A1,CC(C)(C)OC(=O)N1CCN(c2ncc(C(=O)Nc3ccccc3N)s2)CC1>>Nc1ccccc1NC(=O)c1cnc(N2CCNCC2)s1,,C1COCCO1,,Cl,,test
US20140288081A1,CC(C)(C)OC(=O)N1CCC(O)(CC2CC2)CC1>>OC1(CC2CC2)CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US03940394,CCOC(=O)CSc1nccc(Cl)n1.NCc1ccc(Cl)cc1>>CCOC(=O)CSc1nccc(NCc2ccc(Cl)cc2)n1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20130064770A1,O=C1c2ccccc2C(=O)N1CCCCBr.c1ccc(CN2CCNCC2)cc1>>O=C1c2ccccc2C(=O)N1CCCCN1CCN(Cc2ccccc2)CC1,,CC#N,,,,test
US04826991,CCN(CC)C(=O)c1cccc(C)c1.N.N#Cc1ccccc1>>CC(N)N1CCN=C1c1ccccc1,[Zn],,,,,test
US20130029962A1,CC(C(=O)O)c1ccc(C#N)nc1.NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1>>CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)c1ccc(C#N)nc1,,CC#N,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20130165412A1,CCOC(=O)C1(NC(=O)c2nn(-c3ccc(F)cc3F)c3c2C[C@@H]2C[C@H]32)CCC1.N>>NC(=O)C1(NC(=O)c2nn(-c3ccc(F)cc3F)c3c2C[C@@H]2C[C@H]32)CCC1,,CO,,,,test
US20150225367A1,NC1CCN(c2ccc(-c3c[nH]c4cc(F)ccc34)cn2)CC1.O=C1c2ccccc2C(=O)N1CCS(=O)(=O)Cl>>O=C1c2ccccc2C(=O)N1CCS(=O)(=O)NC1CCN(c2ccc(-c3c[nH]c4cc(F)ccc34)cn2)CC1,,CN(C)C=O,ClCCl,CCN(CC)CC,,test
US05654298,CCNc1ccccc1.Cc1cc(Cl)cc(C)[n+]1-c1ccccc1.[Cl-]>>CCN(c1ccccc1)c1cc(C)[n+](-c2ccccc2)c(C)c1.[Cl-],,CCO,,,,test
US20100063068A1,CCOC(=O)C(=C(O)c1ccc(F)cc1)c1cc(Br)ccc1[N+](=O)[O-]>>CCOC(=O)c1c(-c2ccc(F)cc2)[nH]c2ccc(Br)cc12,[Fe],CCO,CCOC(C)=O,CC(=O)O,,test
US20040167224A1,CC(C)(C)O.Clc1ccnc(Cl)n1>>CC(C)(C)Oc1nccc(Cl)n1,,CC(C)(C)O,,CCOC(C)=O,CC(C)(C)[O-].[K+],test
US20090215843A1,COC(=O)c1ccc(CCC(/C=C/c2ccccc2OCc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)Cc2ccc(C#N)cc2)cc1.C[Si](C)(C)N=[N+]=[N-]>>COC(=O)c1ccc(CCC(/C=C/c2ccccc2OCc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)Cc2ccc(-c3nnn[nH]3)cc2)cc1,,Cc1ccccc1,,CCCC[Sn](=O)CCCC,,test
US20050239881A1,CCOC(=O)Cc1ccc(CC)c(O)c1.Fc1cc(Cl)ccc1Br>>CCOC(=O)Cc1ccc(CC)c(Oc2cc(Cl)ccc2Br)c1,,CN1CCCC1=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US03953596,C1CC2CNCC1O2.O=C(Cl)C12CC3CC(CC(C3)C1)C2>>O=C(N1CC2CCC(C1)O2)C12CC3CC(CC(C3)C1)C2,,O,,Cl,[Na+].[OH-],test
US04220646,C#CC(=O)O.O=C(OC1C2=C(OCCS2)C(=O)N1c1ccc2ccc(Cl)nc2n1)N1CCNCC1>>C#CC(=O)N1CCN(C(=O)OC2C3=C(OCCS3)C(=O)N2c2ccc3ccc(Cl)nc3n2)CC1,,CO,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,,test
US06162832,Cl.Nc1ccccc1Oc1ccc(OCc2cccc([N+](=O)[O-])c2)cc1>>Cl.Nc1ccccc1Oc1ccc(OCc2cccc([N+](=O)[O-])c2)cc1,,CCOC(C)=O,,,,test
US20100256163A1,O=S(=O)(c1cccc(C2CCNCC2)c1F)C(F)(F)F.OCCI>>O=S(=O)(c1cccc(C2CCN(CCO)CC2)c1F)C(F)(F)F,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04336255,N=C(N)N.O=[N+]([O-])c1c(Cl)ncnc1Cl>>N=C(N)Nc1ncnc(Cl)c1[N+](=O)[O-],,CCO,,,,test
US06582351B1,NC(=O)c1cnc(O)c([N+](=O)[O-])c1.O=P(Cl)(Cl)Cl>>N#Cc1cnc(Cl)c([N+](=O)[O-])c1,,O=P(Cl)(Cl)Cl,,ClP(Cl)(Cl)(Cl)Cl,,test
US20140206663A1,CC(C)(C)OC(=O)N1CC(=O)C1.CC1C(=O)NN=C2CCc3ccc(N)cc3N21>>CC1C(=O)NN=C2CCc3ccc(NC4CN(C(=O)OC(C)(C)C)C4)cc3N21,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US20080306061A1,CC(C)(C)OC(=O)NC1CCNC1.IC1CCCC1>>CC(C)(C)OC(=O)NC1CCN(C2CCCC2)C1,,CC#N,,CCN(CC)CC,,test
US05508280,ClCC=C1c2ccccc2C=Cc2ccccc21.NCc1ccccc1>>C1=Cc2ccccc2C(=CCNCc2ccccc2)c2ccccc21,,CC#N,,,,test
US20130338196A1,COC(=O)c1cccc(-c2cnc(C(=O)C3CCc4cc(-c5ccccc5)ccc4C3)o2)n1>>O=C(O)c1cccc(-c2cnc(C(=O)C3CCc4cc(-c5ccccc5)ccc4C3)o2)n1,,CC(=O)O,CCOC(C)=O,,,test
US20070185103A1,CC(C)(C)Cc1ccc(F)nc1.CC(C)(C)[Si](C)(C)OC1(CC=O)CCC1>>CC(C)(C)Cc1cnc(F)c(C(O)CC2(O[Si](C)(C)C(C)(C)C)CCC2)c1,,C1CCOC1,O,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US20120184553A1,COC(=O)c1cc(I)ccc1O.Fc1ccc(CBr)cc1>>COC(=O)c1cc(I)ccc1OCc1ccc(F)cc1,,CC(C)=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20020052397A1,OCCN1CCOCC1.Oc1cccc(I)c1>>Ic1cccc(OCCN2CCOCC2)c1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160016947A1,CCOC(=O)C(=O)CC(=O)CC.CNN>>CCOC(=O)c1cc(CC)nn1C,,Cc1ccccc1,,,,test
US08629158B2,Clc1cc(OCc2ccccn2)ccn1.O=CO>>O=c1cc(OCc2ccccn2)cc[nH]1,,O,O=CO,C,O=C[O-].[NH4+],test
US20120208791A1,COC(=O)c1ccn2c(I)cnc2c1.NN>>NNC(=O)c1ccn2ccnc2c1,,CCO,,O,,test
US20070219230A1,CC(C)CI.Cc1[nH]c2c(Cl)nccc2c1C>>Cc1c(C)n(CC(C)C)c2c(Cl)nccc12,,C1CCOC1,,O,[H-].[Na+],test
US20070191447A1,CC(C)(C)OC(=O)COc1cc(Br)cc([N+](=O)[O-])c1N>>O=C1COc2cc(Br)cc([N+](=O)[O-])c2N1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20060147747A1,Brc1ccccn1.Nc1ccccc1[N+](=O)[O-]>>O=[N+]([O-])c1ccccc1Nc1ccccn1,I[Cu]I,CCOC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040152693A1,CC1Cc2cc3c(cc2C(c2ccc([N+](=O)[O-])cc2)=NN1C(N)=S)OCO3.CCOC(CBr)OCC>>CC1Cc2cc3c(cc2C(c2ccc([N+](=O)[O-])cc2)=NN1c1nccs1)OCO3,,O,,CN(C)C=O,,test
US20090105231A1,O=[N+]([O-])c1ccc(-c2ccncc2F)cc1>>Nc1ccc(-c2ccncc2F)cc1,Cl[Fe](Cl)Cl,CCO,,NN,O,test
US20050222230A1,COc1ccc(-c2coc3cc(O)c(Cl)cc3c2=O)cc1OC.NN>>COc1ccc(-c2c[nH]nc2-c2cc(Cl)c(O)cc2O)cc1OC,,CCO,,O,,test
US20100261750A1,C[C@@H]1CCNC1.O=[N+]([O-])c1ccc(F)cc1C(F)(F)F>>C[C@H]1CCN(c2ccc([N+](=O)[O-])c(C(F)(F)F)c2)C1,,CC#N,,CCN(CC)CC,,test
US05288928,C/C(=C\c1ccccc1)CO>>C[C@H](CO)Cc1ccccc1,,Cc1ccccc1,,O=O,,test
US06329381B1,BrCC1CCCCC1.Nc1nc(S)nc2c1nc(O)n2Cc1ccccc1>>Nc1nc(SCC2CCCCC2)nc2c1nc(O)n2Cc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06008230,Nc1cccc2c(OC(=O)c3c(Cl)cccc3Cl)ccnc12.O=C(Cl)c1c(Cl)cccc1Cl>>O=C(Nc1cccc2c(OC(=O)c3c(Cl)cccc3Cl)ccnc12)c1c(Cl)cccc1Cl,,ClCCCl,ClCCl,CCN(CC)CC,,test
US20070185153A1,CC(C)(C)OC(=O)NC[C@H]1CN(Cc2ccccc2)CCO1>>CC(C)(C)OC(=O)NC[C@H]1CNCCO1,[Pd],CCO,,,,test
US05852045,CCC(O)c1cccnc1.ClC(Cl)(Cl)Cl>>ClCCCc1ccncc1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090247517A1,CC(C)c1ccc(-c2nc3c(-c4ccccc4)nn(CC(=O)O)c3c(=O)n2-c2ccc(Cl)cc2)cc1.N>>CC(C)c1ccc(-c2nc3c(-c4ccccc4)nn(CC(N)=O)c3c(=O)n2-c2ccc(Cl)cc2)cc1,,CN(C)C=O,CO,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040092556A1,COC(=O)c1ccc(CCBr)cc1.NCc1ccccn1>>COC(=O)c1ccc(CCNCc2ccccn2)cc1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US04935420,CCOC(=O)c1cn(C2CC2)c2c(COC(C)=O)c(N3CCOCC3)c(F)cc2c1=O>>CCOC(=O)c1cn(C2CC2)c2c(CO)c(N3CCOCC3)c(F)cc2c1=O,,CCO,O,O=C([O-])[O-].[K+].[K+],,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4ccccc4)nc(Cl)c3n2)cc1.Nc1cc[nH]n1>>c1ccc(-c2nc(Nc3cc[nH]n3)c3[nH]ncc3n2)cc1,C1COCCO1,CO,,Cl,,test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(NS(=O)(=O)c2ccc(C)cc2)nc1-c1ccc(C)cc1>>CCCC(C(=O)O)c1c(C)nc(NS(=O)(=O)c2ccc(C)cc2)nc1-c1ccc(C)cc1,,CO,,[Na+].[OH-],,test
US20060229309A1,Br[Mg]c1ccccc1.CC(C)(C)OC(=O)N1CC(=O)C[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](Cc1cc(F)cc(F)c1)NC(=O)c1cccc(C(N)=O)c1>>CC(C)(C)OC(=O)N1CC(O)(c2ccccc2)C[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](Cc1cc(F)cc(F)c1)NC(=O)c1cccc(C(N)=O)c1,,C1CCOC1,,O,,test
US06251911B1,CSC(Nc1ccc(CNC(=O)OC(C)(C)C)cc1)=C(C#N)C#N.NN>>CC(C)(C)OC(=O)NCc1ccc(Nc2n[nH]c(N)c2C#N)cc1,,CO,,O,,test
US20080234255A1,C=CCN(CC(C)C(=O)OC)c1nc(Cl)ncc1[N+](=O)[O-]>>C=CCN1CC(C)C(=O)Nc2cnc(Cl)nc21,[Fe],CC(=O)O,,,,test
US20110124647A1,CC(NC(=O)NCCCl)c1ccccc1Cl>>CC(NC1=NCCO1)c1ccccc1Cl,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20160237069A1,Cl.N#C[N-]C#N.Nc1ccc(Cl)c(Cl)c1>>Cl.N=C(N)Nc1ccc(Cl)c(Cl)c1,,CC(C)O,,,,test
US20040092503A1,CC(C)CNc1ccc2nc(S)sc2c1.O=C(Cl)Oc1ccc(Cl)cc1>>CCC(C)N(C(=O)Oc1ccc(Cl)cc1)c1ccc2nc(S)sc2c1,,CC(C)=O,,CCN(C(C)C)C(C)C,,test
US06433211B1,N#Cc1cccc(C(N)=O)c1.O=S(=O)(O)O>>N#Cc1cccc(C(=O)O)c1,,O=S(=O)(O)O,,O=N[O-].[Na+],,test
US20100311730A1,N#Cc1cnc(Nc2cc(Cl)ncn2)cn1.NCC1CCOCC1>>N#Cc1cnc(Nc2cc(NCC3CCOCC3)ncn2)cn1,,CC#N,,CCN(CC)CC,,test
US06599917B1,COCC(=O)Cc1ccccc1.Nc1cc(Br)ccc1C=O>>COc1cc2ccc(Br)cc2nc1Cc1ccccc1,,O,,CCO,[K+].[OH-],test
US20070249585A1,CN(C)S(=O)(=O)Cl.Clc1ccc2c(c1)CNCc1nnc(N3CCC(c4ccccc4)CC3)n1-2>>CN(C)S(=O)(=O)N1Cc2cc(Cl)ccc2-n2c(nnc2N2CCC(c3ccccc3)CC2)C1,,ClCCl,O,CCN(CC)CC,,test
US20110015189A1,C#CC1CC1.CC1(C)[C@@]2(C)CC[C@]1(C(=O)N(C(=O)[C@@]13CC[C@@](C)(C(=O)O1)C3(C)C)c1ccc(Cl)cc1C(=O)C(F)(F)F)OC2=O>>CC1(C)[C@@]2(C)CC[C@]1(C(=O)Nc1ccc(Cl)cc1[C@@](O)(C#CC1CC1)C(F)(F)F)OC2=O,,C1CCOC1,C1CCOC1,[Li]CCCC,,test
US20080207654A1,CCOc1nc(C)c(-c2ccc(OC(C)C)cc2)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCOc1nc(C)c(-c2ccc(OC(C)C)cc2)c(=O)n1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20090312370A1,C=CCBr.COCc1cc(NC(=O)OCc2ccccc2)cc(C(=O)OC)c1>>C=CCN(C(=O)OCc1ccccc1)c1cc(COC)cc(C(=O)OC)c1,,CN(C)C=O,,[H-].[Na+],,test
US20080146569A1,COC(=O)c1ccc(Cl)nc1.OB(O)c1ccccc1O>>COC(=O)c1ccc(-c2ccccc2O)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20100324030A1,O=C1COc2ccc(C(O)CN3CCN(C(=O)OCc4ccccc4)CC3)cc2N1>>O=C1COc2ccc(C(O)CN3CCNCC3)cc2N1,[Pd],CCOC(C)=O,,,,test
US20120258952A1,BrCc1ccccc1.O=[N+]([O-])c1cccc2[nH]nc(I)c12>>O=[N+]([O-])c1cccc2c1c(I)nn2Cc1ccccc1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20100331318A1,CCOC(=O)CC(=O)OCC.COc1ccc2ccc(F)c(CBr)c2n1>>CCOC(=O)C(Cc1c(F)ccc2ccc(OC)nc12)C(=O)OCC,,C1CCOC1,,[H-].[Na+],,test
US20060177943A1,CC(C)(C)[Si](C)(C)Oc1cc(OCCOCCOCCOCCOCCOC(c2ccccc2)(c2ccccc2)c2ccccc2)cc(O[Si](C)(C)C(C)(C)C)c1>>Oc1cc(O)cc(OCCOCCOCCOCCOCCOC(c2ccccc2)(c2ccccc2)c2ccccc2)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120077809A1,N#CC(c1ccc(Cl)nn1)c1c(Cl)cccc1Cl.O=C(NCc1ccccc1S)c1cc(F)cc(N2CCOCC2)c1>>N#CC(c1ccc(Sc2ccccc2CNC(=O)c2cc(F)cc(N3CCOCC3)c2)nn1)c1c(Cl)cccc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US04661477,CCOP([O-])OCC.COCCCN>>CCOP=O.COCCC[NH3+],,CCO,,O,,test
US20040072839A1,CCOC(CBr)OCC.O=C(Cc1ccccc1OC(F)(F)F)C1CCCCC1>>CCOC(CC(C(=O)C1CCCCC1)c1ccccc1OC(F)(F)F)OCC,,CS(C)=O,O,CC(C)(C)[O-].[K+],,test
US05037819,COC(=O)[C@H]1[C@H](CCCNC(=NC(=O)OCc2ccccc2)NC(=O)OCc2ccccc2)C(=O)N1S(=O)(=O)c1ccc(C)cc1.Cl>>COC(=O)[C@H]1[C@H](CCCNC(=N)N)C(=O)N1S(=O)(=O)c1ccc(C)cc1.Cl,[Pd],CCOC(C)=O,CO,[H][H],,test
US20020037891A1,CCOC(=O)c1cn(C)c2nc3cc(N4CCN(c5ccc(F)cc5)CC4)c(F)cc3cc2c1=O>>Cn1cc(C(=O)O)c(=O)c2cc3cc(F)c(N4CCN(c5ccc(F)cc5)CC4)cc3nc21,,CC(=O)O,Cl,O,,test
US20150158878A1,CCOC(=O)c1coc(Cl)n1.OB(O)c1ccc2c(c1)CCO2>>CCOC(=O)c1coc(-c2ccc3c(c2)CCO3)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20140162980A1,CSc1cc(C)nc2c1CCCC2=O.O=C(OO)c1cccc(Cl)c1.O=C([O-])O>>Cc1cc(S(C)(=O)=O)c2c(n1)C(=O)CCC2,,ClCCl,,O,,test
US20120302586A1,Cc1cc(Cl)n2nc(C(C)(F)F)nc2n1.Nc1ccc(S(F)(F)(F)(F)F)cc1>>Cc1cc(Nc2ccc(S(F)(F)(F)(F)F)cc2)n2nc(C(C)(F)F)nc2n1,,CCO,,,,test
US20100249163A1,COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(OCCOC)c2ccc(F)c(F)c2)C2CC2)cc(OCCOC)c1>>COCCCc1cc(CN(C(=O)[C@H]2CNCC[C@]2(OCCOC)c2ccc(F)c(F)c2)C2CC2)cc(OCCOC)c1,,ClCCl,,Cl,,test
US20120277423A1,C/C=C/C(=O)Cl.COc1ccccc1>>C/C=C/C(=O)c1ccc(OC)cc1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20020013460A1,CCN1CCNCC1.COc1ccc(-c2cc3ccccc3c(Cl)n2)cc1>>CCN1CCN(c2nc(-c3ccc(OC)cc3)cc3ccccc23)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05856334,Nc1cccc2c1NCCC2=O.O=CCCc1ccccc1>>O=C1CCn2c(CCc3ccccc3)nc3cccc1c32,,CO,,Cl,,test
US05021429,CN(C)Cc1cccc(OCCCN2C(=O)c3ccccc3C2=O)c1>>CN(C)Cc1cccc(OCCCN)c1,,CCOCC,,CN,,test
US05397798,NCCc1cc[nH]n1.O=c1[nH]c2ccccc2c(=O)o1>>Nc1ccccc1C(=O)NCCc1cc[nH]n1,,C1COCCO1,CCOC(C)=O,O,,test
US04243678,CC(=O)Cl.CCOC(=O)CCCCCNC(c1ccccc1)c1ccccc1>>CCOC(=O)CCCCCN(C(C)=O)C(c1ccccc1)c1ccccc1,,c1ccccc1,,CCN(C(C)C)C(C)C,CS(C)=O,test
US20150376195A1,CC(C)(C)OC(=O)N1CCCC1(COCc1ccccc1)C(=O)NCC(=O)N1CCCC1>>CC(C)(C)OC(=O)N1CCCC1(CO)C(=O)NCC(=O)N1CCCC1,[Pd],CO,,,,test
US04840963,NS(=O)(=O)c1cc2cc3c(cc2n1S(=O)(=O)c1ccccc1)OCO3>>NS(=O)(=O)c1cc2cc3c(cc2[nH]1)OCO3,,O,,[Na+].[OH-],,test
US20090275592A1,CC(C)(C)OC(=O)N1C(=O)CC[C@@H]1Cc1ccc(C(F)(F)F)cc1.NN>>CC(C)(C)OC(=O)N[C@H](CCNN)Cc1ccc(C(F)(F)F)cc1,,C1CCOC1,,,,test
US20100256127A1,CCCCc1noc(CO)c1COc1ccc(C(=O)OC)cn1>>CCCCc1noc(CO)c1COc1ccc(C(=O)O)cn1,,C1COCCO1,,[Na+].[OH-],,test
US20150210688A1,COCc1nc(I)c(I)[nH]1>>COCc1ncc(I)[nH]1,,CCO,O,O=S([O-])[O-].[Na+].[Na+],,test
US20160052884A1,COC(=O)c1ccccc1NC(=O)C(CC1CCCCO1)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O>>COc1cn(C(CC2CCCCO2)C(=O)Nc2ccccc2C(=O)O)c(=O)cc1-c1cc(Cl)ccc1C#N,,CO,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130317001A1,CC(C)(C)OC(=O)c1cc(C2CC2)c(O[C@H]2C[C@@H]3CC[C@H]2C3)cc1F>>O=C(O)c1cc(C2CC2)c(O[C@H]2C[C@@H]3CC[C@H]2C3)cc1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US05661169,COc1cc(C)ccc1[N+](=O)[O-].O=C1CCC(=O)N1Br>>COc1cc(CBr)ccc1[N+](=O)[O-],O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US05602170,O=C(O)CC(=O)O.O=Cc1ccc(-c2cccs2)s1>>O=C(O)C=Cc1ccc(-c2cccs2)s1,,O,c1ccncc1,C1CCNCC1,Cl,test
US20120238540A1,CC(C)(C)OC(=O)NCCOCCOS(C)(=O)=O.COc1cc([N+](=O)[O-])ccc1O>>COc1cc([N+](=O)[O-])ccc1OCCOCCNC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120108638A1,CCc1cc(C(=N)NO)cc(C)c1O.COc1cc(C(=O)O)cc(C2CCCC2)n1>>CCc1cc(-c2noc(-c3cc(OC)nc(C4CCCC4)c3)n2)cc(C)c1O,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20160244437A1,CC(C)(C)OC(=O)N1CC[C@@H](N)C1.COc1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1-c1ccc(C(=O)O)cc1C>>COc1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1-c1ccc(C(=O)N[C@@H]2CCN(C(=O)OC(C)(C)C)C2)cc1C,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090093476A1,O=C(Cc1ccc([N+](=O)[O-])c(F)c1)N1CCOCC1>>O=[N+]([O-])c1ccc(CCN2CCOCC2)cc1F,,C1CCOC1,,Cl,,test
US20050176689A1,CCc1cc(O)cc2c1C(=O)CCC2(C)C.O=S(=O)(N(c1ccc(Cl)cn1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CCc1cc(OS(=O)(=O)C(F)(F)F)cc2c1C(=O)CCC2(C)C,CN(C)c1ccncc1,CCCCCC,ClCCl,CCOC(C)=O,,test
US20060189626A1,CN1CCNCC1.Cc1ncccc1-c1cc(Cl)ncc1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1ncccc1-c1cc(N2CCN(C)CC2)ncc1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1,,ClCCl,,,,test
US20130317065A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(C(C)O)cc1N>>Cc1ccc(C(C)O)cc1NC(=O)OC(C)(C)C,,C1CCOC1,,,,test
US04634715,CC(C)(C)OC(=O)NN.CCOC(=O)C(=O)CCc1ccccc1>>CCOC(=O)C(CCc1ccccc1)NNC(=O)OC(C)(C)C,,C1CCOC1,,[BH3-]C#N.[Na+],,test
US05095022,C1=Cc2ccccc2C(=C2CCNCC2)c2ccccc21.C=CC(=O)OCC>>O=C(O)CCN1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1,,CO,,[Na+].[OH-],,test
US20070225267A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1CC(COc2ccccc2)OCC1[C@@H](O)[C@@H](N)Cc1cc(F)cc(F)c1>>CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)[C@H]1CO[C@@H](COc2ccccc2)CN1C(=O)OC(C)(C)C,,C1CCOC1,,CCN(CC)CC,,test
US20100029650A1,CS(=O)(=O)c1ccc(-c2ccc(O)cc2)cc1.Cc1noc(N2CCC(CO)CC2)n1>>Cc1noc(N2CCC(COc3ccc(-c4ccc(S(C)(=O)=O)cc4)cc3)CC2)n1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150274767A1,CC(C)[Si](Cl)(O[Si](Cl)(C(C)C)C(C)C)C(C)C.Nc1ncnc2c([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)cnn12>>CC(C)[Si]1(C(C)C)OC[C@H]2O[C@@H](c3cnn4c(N)ncnc34)[C@H](O)[C@@H]2O[Si](C(C)C)(C(C)C)O1,,CN(C)C=O,O,c1c[nH]cn1,,test
US20130178459A1,CI.C[C@@H](CNC(=O)OC(C)(C)C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>C[C@@H](CN(C)C(=O)OC(C)(C)C)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20070004675A1,COc1ccccc1NC(=O)CC(=O)O.Nc1ccc(Oc2ccnc3cc(-c4ccc(CN5CCCC5)cc4)sc23)c(F)c1>>COc1ccccc1NC(=O)CC(=O)Nc1ccc(Oc2ccnc3cc(-c4ccc(CN5CCCC5)cc4)sc23)c(F)c1,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20120053180A1,CCc1cnc(OC2CCC(N=[N+]=[N-])CC2)nc1>>CCc1cnc(OC2CCC(N)CC2)nc1,O=[Pt]=O,CO,,,,test
US20120101105A1,C[C@@H](NC(=O)COc1ccc(Br)cc1)c1ccc(OCC(F)(F)F)cn1.OB(O)C1CC1>>C[C@@H](NC(=O)COc1ccc(C2CC2)cc1)c1ccc(OCC(F)(F)F)cn1,,C1COCCO1,CO,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US03957819,O=S(Cl)Cl.OCCCNC1=Nc2ccccc2C1(O)c1cccc(Cl)c1>>OC1(c2cccc(Cl)c2)C(NCCCCl)=Nc2ccccc21,,ClC(Cl)Cl,,,,test
US20100010053A1,CCOC(=O)CCC(=O)c1c[nH]c2c(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)cccc12>>CC(C)Oc1ccc(-c2nc(-c3cccc4c(C(=O)CCC(=O)O)c[nH]c34)no2)cc1Cl,,C1CCOC1,,Cl,[Na+].[OH-],test
US20150376120A1,CC(C)(C)OC(=O)N[C@@H](CC#N)C(=O)Nc1ccc(C(=O)OC(C)(C)C)nc1.Cl>>N#CC[C@H]([NH3+])C(=O)Nc1ccc(C(=O)O)nc1.[Cl-],,C1COCCO1,,,,test
US20090156593A1,CNC1(c2cccs2)CCC2(CC1)OCCO2>>CNC1(c2cccs2)CCC(=O)CC1,,O,,Cl,,test
US05506266,CCCCCC(=O)Cl.CNO>>CCCCCC(=O)N(C)O,,CO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20020156296A1,CC(C)(C)c1cc2c(cc1O)CC1(CCCCCC1)O2.CC=CCBr>>CC=CCOc1cc2c(cc1C(C)(C)C)OC1(CCCCCC1)C2,,CN(C)C=O,,[H-].[Na+],,test
US05773618,O=C(Cl)CCCl.O=[N+]([O-])c1ccc2c(c1)NCC2>>O=C(CCCl)N1CCc2ccc([N+](=O)[O-])cc21,,CC(C)=O,,Cl,,test
US20120010189A1,Cc1cc(CN2CCOCC2)ccc1OC1CN(C(=O)OC(C)(C)C)C1>>Cc1cc(CN2CCOCC2)ccc1OC1CNC1,,CO,,Cl,,test
US20120322833A1,FC(F)(F)c1cc(C2(C(F)(F)F)CCN(Cc3ccccc3)C2)cc(C(F)(F)F)n1>>FC(F)(F)c1cc(C2(C(F)(F)F)CCNC2)cc(C(F)(F)F)n1,,CC(Cl)Cl,,CC(Cl)OC(=O)Cl,,test
US20140142083A1,CC=O.COC(=O)c1cc(Cl)cc(NC2CCOCC2)c1OC>>CCN(c1cc(Cl)cc(C(=O)OC)c1OC)C1CCOCC1,,ClCCCl,O,CC(=O)O,O=C([O-])O.[Na+],test
US20110092485A1,CCCN(CCC)C(=O)C1=Cc2ccc(-c3ccc(O)cc3)cc2N=C(NC(=O)OC(C)(C)C)C1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CCCN(CCC)C(=O)C1=Cc2ccc(-c3ccc(OS(=O)(=O)C(F)(F)F)cc3)cc2N=C(NC(=O)OC(C)(C)C)C1,,ClCCl,,,,test
US20100216839A1,CC(C)(C)OC(=O)N[C@H]1C[C@@H](O)CN(C(=O)OCc2ccccc2)C1>>CC(C)(C)OC(=O)N[C@H]1CC(=O)CN(C(=O)OCc2ccccc2)C1,,CCOC(C)=O,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20030195363A1,CC(C)c1cn(-c2ccncc2)c(COCc2ccccc2)n1>>CC(C)c1cn(-c2ccncc2)c(CO)n1,,Cl,,Cc1ccccc1,O,test
US20080269196A1,CC(C)(C)OC(=O)NCc1ccc(C#CC2CCCCC2)cc1>>CC(C)(C)OC(=O)NCc1ccc(/C=C\C2CCCCC2)cc1,[Pd],CCOC(C)=O,,,,test
US20120208796A1,CN.COC(=O)c1cc(N2CCN3CCC2CC3)ncc1[N+](=O)[O-]>>CNC(=O)c1cc(N2CCN3CCC2CC3)ncc1[N+](=O)[O-],,CO,,,,test
US20110059999A1,CN(C)C1(c2cccc(F)c2)CCC(C=O)CC1.Cl[Mg]Cc1ccccc1>>CN(C)C1(c2cccc(F)c2)CCC(C(O)Cc2ccccc2)CC1,,C1CCOC1,,[Cl-].[NH4+],,test
US04610821,O=C(N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)Nc1ccccc1)OCc1ccccc1>>N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)Nc1ccccc1,,CCOCC,,Br,CC(=O)O,test
US20110065764A1,N[C@@H]1CCC[C@H](O)C1.O=C(O)c1noc(-c2ccc(Cl)cc2)c1Cl>>O=C(N[C@@H]1CCC[C@H](O)C1)c1noc(-c2ccc(Cl)cc2)c1Cl,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US05587510,COC(=O)/C(=C/c1ccccc1)CCl>>O=C(O)/C(=C/c1ccccc1)CCl,,CC(=O)O,,Cl,,test
US20040009966A1,CCOC1OC(=O)CC1NC(=O)CN1CC=CCC(NC(=O)c2nccc3ccccc23)C1=O>>O=C(CN1CC=CCC(NC(=O)c2nccc3ccccc23)C1=O)NC1CC(=O)OC1O,,CC#N,O,O=C(O)C(F)(F)F,,test
US04999448,COCOc1ccccc1C=O.COCOc1ccccc1Cl>>COCOc1ccccc1C(O)c1cccc(Cl)c1OCOC,,C1CCOC1,CCCCCC,CN(C)CCN(C)C,[Li]CCCC,test
US20110040092A1,C(=C/c1ccccc1)\c1ccccc1.O>>c1ccc([C@@H]2O[C@H]2c2ccccc2)cc1,,CC#N,,ClCCl,,test
US20160024091A1,c1cc(-n2cnnn2)ncc1C1CO1>>OCCc1ccc(-n2cnnn2)nc1,[Pd],CCO,,O=C[O-].[NH4+],,test
US04145432,CCOC(=O)C1=C(C)NC(C=O)=C(C(=O)OCC)C1c1ccccc1OC>>CCOC(=O)C1=C(C)NC(CO)=C(C(=O)OCC)C1c1ccccc1OC,,CCO,,Cl,[BH4-].[Na+],test
US20150368246A1,COC(=O)C(OC)(OC)OC.Nc1ccc(Cl)nc1-c1cc2c(F)cccc2[nH]1>>COC(=O)c1nc2ccc(Cl)nc2c2cc3c(F)cccc3n12,,C1COCCO1,,Cl,,test
US20120040954A1,BrC(Br)(Br)Br.COc1ccc2c(=O)[nH]c(-c3cc(C)c(OCCO)c(C)c3)nc2c1>>COc1ccc2c(=O)[nH]c(-c3cc(C)c(OCCBr)c(C)c3)nc2c1,,CN(C)C=O,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20160237090A1,COC(C)(C)OC.O=C1OC[C@@H](O)[C@H]1O>>CC1(C)O[C@@H]2COC(=O)[C@@H]2O1,,CC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20130225620A1,C1CCNC1.Cc1c(Br)cc(F)cc1[N+](=O)[O-]>>Fc1cc(Br)c2cc[nH]c2c1,[Fe],C1COCCO1,,CC(=O)O,[Na+].[OH-],test
US03932407,O=C(O)CNCCCc1ccccc1[N+](=O)[O-]>>Nc1ccccc1CCCNCC(=O)O,[Pd],CCO,,[H][H],,test
US20020132818A1,COC(=O)CCc1nc(Cl)c2c3c(sc2n1)CCCC3.COc1ccc(CN)cc1Cl>>COC(=O)CCc1nc(NCc2ccc(OC)c(Cl)c2)c2c3c(sc2n1)CCCC3,,CN1CCCC1=O,,,,test
US20140045852A1,CC(C)(C)S(=O)(=O)Cc1cccc(N)c1.Clc1ncnc(Cl)n1>>CC(C)(C)S(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1,,C1CCOC1,CC(C)O,CCN(C(C)C)C(C)C,,test
US20130296436A1,CCC(=O)CBr.Cc1cc(Br)c(C)cc1O>>CCC(=O)COc1cc(C)c(Br)cc1C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20040072833A1,CCCCN(CC)c1c2c(nc3c(-c4ccc(OC)cc4C)c(COC)nn13)CCC2>>CCCCN(CC)c1c2c(nc3c(-c4ccc(O)cc4C)c(CO)nn13)CCC2,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20040122000A1,CC(C)CN(C[C@@H](O)[C@H](Cc1ccc(OCCO)cc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1ccc2c(c1)OCO2.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCCOc2ccc(C[C@H](NC(=O)O[C@H]3CO[C@H]4OCC[C@@H]34)[C@H](O)CN(CC(C)C)S(=O)(=O)c3ccc4c(c3)OCO4)cc2)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20050080074A1,CC(C(=O)OC(C)(C)C)N1C(=O)c2c(cccc2C(F)(F)F)C1C#N.Cl>>CC(C(=O)O)N1C(=O)c2c(cccc2C(F)(F)F)C1CN.Cl,[Pd],CO,,[H][H],,test
US20090270363A1,BrCCCCBr.N#Cc1ccc(N)cc1Cl>>N#Cc1ccc(N2CCCC2)cc1Cl,,CCN(CC)CC,Cc1ccccc1,,,test
US20150259338A1,Fc1ccc([C@H]2C[C@@H]3CCC[C@H]2N3)cn1>>Fc1ccc([C@@H]2C[C@H]3CCC[C@@H]2N3)cn1,,ClC(Cl)Cl,,,,test
US20100196321A1,CCN(C(=O)Cl)C(C)C.CCN(C(C)C)C(C)C.COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)NS(=O)(=O)C6CC6)C[C@H]5C=CCCCCC[C@H](N)C(=O)N4C3)cc(-c3nc(C4CC4)cs3)nc2c1C.COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)NS(=O)(=O)C6CC6)C[C@H]5C=CCCCCC[C@H](N)C(=O)N4C3)cc(-c3nc(C4CC4)cs3)nc2c1Cl>>CCN(C(=O)N[C@H]1CCCCCC=C[C@@H]2C[C@@]2(C(=O)NS(=O)(=O)C2CC2)NC(=O)[C@@H]2C[C@@H](Oc3cc(-c4nc(C5CC5)cs4)nc4c(C)c(OC)ccc34)CN2C1=O)C(C)C.COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)NS(=O)(=O)C6CC6)C[C@H]5C=CCCCCC[C@H](N)C(=O)N4C3)cc(-c3nc(C(C)C)cs3)nc2c1C.Cl.Cl,CN(C)c1ccncc1,C1CCOC1,,Cl,Cl,test
US20080207708A1,CC(C)(C)OC(=O)Nc1csc(Cc2cc(Cl)ccc2OCc2ccccc2)n1>>Nc1csc(Cc2cc(Cl)ccc2OCc2ccccc2)n1,,CC#N,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100261727A1,Clc1ccnc(Cl)n1.OCCF>>FCCOc1ccnc(Cl)n1,,O,,C1CCOC1,[H-].[Na+],test
US20010031869A1,CC(C)(C)C(=O)Oc1cccc(N2c3ccccc3Cc3ccccc32)c1>>Oc1cccc(N2c3ccccc3Cc3ccccc32)c1,,CO,,[Na+].[OH-],,test
US20120108572A1,CI.Cc1ccc(C(=O)O)cc1Oc1ccnc(Cl)c1>>COC(=O)c1ccc(C)c(Oc2ccnc(Cl)c2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150284409A1,C=CCC[C@@H](C)O.CC[C@@H]1[C@@H](C(=O)OC)N1C(=O)OC(C)(C)C>>C=CCC[C@@H](C)O[C@@H](CC)[C@H](NC(=O)OC(C)(C)C)C(=O)OC,,ClCCl,,CCOCC,FB(F)F,test
US20110098320A1,CCOC(=O)CBr.O=C(CCCl)c1ccccc1>>CCOC(=O)CC(O)(CCCl)c1ccccc1,[Zn],C1CCOC1,,II,,test
US20020032208A1,COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1O.Cl.ClCc1ccncc1>>COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCc1ccncc1.Cl,,CN(C)C=O,,[I-].[K+],,test
US20110015175A1,COc1cc([N+](=O)[O-])ccc1-n1cnc(C(F)F)c1>>COc1cc(N)ccc1-n1cnc(C(F)F)c1,[Pd],CO,,,,test
US20130310334A1,CC(C)(C)c1ccc(N=C=O)cc1.COc1ccc(CNc2ncnc3c2ccn3[C@@H]2O[C@H](CN(CCCN)C(C)C)[C@H]3OC(C)(C)O[C@H]32)c(OC)c1>>COc1ccc(CNc2ncnc3c2ccn3[C@@H]2O[C@H](CN(CCCNC(=O)Nc3ccc(C(C)(C)C)cc3)C(C)C)[C@H]3OC(C)(C)O[C@H]32)c(OC)c1,,ClCCl,,,,test
US20100087427A1,COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2N)C(C)C)ccc1OC.O=C(Cl)c1ccccc1>>COCCCOc1cc(C(=O)N(C[C@H]2CN(C(=O)OC(C)(C)C)C[C@@H]2NC(=O)c2ccccc2)C(C)C)ccc1OC,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20070191293A1,CC1(C)O[C@@H]2[C@H](O1)[C@@H](COS(N)(=O)=O)C[C@H]2n1ccc2c(Sc3ccccc3)ncnc21>>NS(=O)(=O)OC[C@H]1C[C@@H](n2ccc3c(Sc4ccccc4)ncnc32)[C@H](O)[C@@H]1O,,O,O=C(O)C(F)(F)F,,,test
US20030125334A1,CC(C)(C)OC(=O)N(Cc1cccc(F)c1)c1cncc(N2CCNCC2)n1>>Fc1cccc(CNc2cncc(N3CCNCC3)n2)c1,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20080085880A1,COCCOC.CO[C@H]1CC2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@H]([C@H](C)C[C@@H]2CC[C@H](n3cnnn3)[C@H](OC)C2)CC(=O)[C@H](C)C=C(C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=CC=C1C>>COCCOC.CO[C@H]1CC2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@H]([C@H](C)C[C@@H]2CC[C@H](n3cnnn3)[C@H](OC)C2)CC(=O)[C@H](C)C=C(C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=CC=C1C,,COCCOC,,Cc1ccccc1,,test
US20090247568A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Nc1ccc2[nH]ccc2c1>>CC(C)(C)OC(=O)N1CCC(Nc2ccc3[nH]ccc3c2)CC1,,ClCCCl,,CC(=O)O,[Na+].[OH-],test
US20110251186A1,O=C(NC1=NC2(CCS1)c1cc(Br)ccc1Oc1cnc(Cl)cc12)c1ccc([N+](=O)[O-])cc1>>NC1=NC2(CCS1)c1cc(Br)ccc1Oc1cnc(Cl)cc12,,CO,O,Cl,[Na+].[OH-],test
US04065491,C=O.CCOP([O-])OCC.NCC(=O)O>>CCOP(=O)(CNCC(=O)O)OCC,,O,,Cl,[Na+].[OH-],test
US20150252038A1,CC(C)(C)OC(=O)c1cc(C2CC2)c(OCC(CCBr)CCBr)cc1F.NC1c2ccccc2CC1O>>CC(C)(C)OC(=O)c1cc(C2CC2)c(OCC2CCN([C@@H]3c4ccccc4C[C@@H]3O)CC2)cc1F,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US08680272B2,COc1ccc2cc(C#Cc3ccc(N)c(C)c3)ccc2c1.Cc1nc2ccccc2c(=O)o1>>COc1ccc2cc(C#Cc3ccc(-n4c(C)nc5ccccc5c4=O)c(C)c3)ccc2c1,,CC(=O)O,,,,test
US07598377B2,CS(=O)(=O)Cl.Cc1cc(C(C)O)c2oc(-c3ccncc3)cc(=O)c2c1>>Cc1cc(C(C)OS(C)(=O)=O)c2oc(-c3ccncc3)cc(=O)c2c1,,ClCCl,,CCN(CC)CC,,test
US04742052,CCOC(=O)C=Cc1ccc(C(=O)OC(C)(C)C)cc1>>CCOC(=O)CCc1ccc(C(=O)OC(C)(C)C)cc1,[Pd],CCO,,,,test
US04544501,CC1(C)CN1P(=S)(Br)N1CC1(C)C.CN>>CNP(=S)(N1CC1(C)C)N1CC1(C)C,,C1CCOC1,,,,test
US05624937,Brc1ccc2ccccc2c1.O=[N+]([O-])c1ccc(S)cc1>>O=[N+]([O-])c1ccc(Sc2ccc3ccccc3c2)cc1,[Cu],c1ccncc1,,O=C([O-])[O-].[K+].[K+],,test
US20070078121A1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc([N+](=O)[O-])cc1>>CCOC(=O)C=Cc1ccc([N+](=O)[O-])cc1,,ClCCl,,,,test
US20080103141A1,CC(C)(C)OC(=O)N1CCC(CNc2ncc(Br)cn2)CC1.CS(=O)(=O)c1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)N1CCC(CNc2ncc(-c3ccc(S(C)(=O)=O)cc3)cn2)CC1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US04006237,CCOC(=O)c1c(O)c2c([nH]c1=O)CCCC2>>O=c1cc(O)c2c([nH]1)CCCC2,,Cl,,,,test
US20020025959A1,O=C(NCc1ccc(Cl)cc1)c1cnc2c(CNCc3ccccc3)cc(CN3CCOCC3)cc2c1O.O=C(n1ccnc1)n1ccnc1>>O=C(NCc1ccc(Cl)cc1)c1cn2c3c(cc(CN4CCOCC4)cc3c1=O)CN(Cc1ccccc1)C2=O,,CN1CCCC1=O,,,,test
US20080275064A1,Cc1ccc(-c2nc(N)cc(-c3nccs3)n2)o1.O=C(Cl)CCl>>Cc1ccc(-c2nc(NC(=O)CCl)cc(-c3nccs3)n2)o1,,c1ccncc1,,ClCCl,,test
US20080255114A1,C=CCN1CCN[C@@H](CC(C)C)C1.COC(=O)c1cccc2oc(Cl)nc12>>C=CCN1CCN(c2nc3c(C(=O)OC)cccc3o2)[C@@H](CC(C)C)C1,,COCCOC,,[H-].[Na+],,test
US20090264626A1,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)O.CI>>CO[C@@H]1C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1,,CC(C)=O,O,Cl,[Na+].[OH-],test
US20060178373A1,COc1ccc(-c2cc(=O)c3ccc(O)cc3o2)cc1OC.ClCC1CO1>>COc1ccc(-c2cc(=O)c3ccc(OCC4CO4)cc3o2)cc1OC,,CN(C)C=O,,[H-].[Na+],,test
US20150274705A1,CC(C)(C)OC(=O)N1CCC2(CCC(=O)CC2)CC1.N>>CC(C)(C)OC(=O)N1CCC2(CCC(N)CC2)CC1,,CCO,,CO,[BH4-].[Na+],test
US20060074075A1,O=C(O)CS.O=[N+]([O-])c1ccc(Cl)c([N+](=O)[O-])c1>>O=C(O)CSc1ccc([N+](=O)[O-])cc1[N+](=O)[O-],,C1COCCO1,,CCN(CC)CC,O,test
US20120289474A1,COCCCc1noc(C(=O)OC)n1>>COCCCc1noc(CO)n1,,CO,,[BH4-].[Na+],,test
US20100292208A1,O=S(Cl)Cl.OCc1cc2ccc(Oc3nc4ccccc4s3)cc2s1>>ClCc1cc2ccc(Oc3nc4ccccc4s3)cc2s1,,ClCCl,,,,test
US05514680,Nc1c([N+](=O)[O-])cc(F)cc1C(F)(F)F>>Nc1cc(F)cc(C(F)(F)F)c1N,,CCO,,Cl[Sn]Cl,,test
US20090093459A1,CC(C)(C)C(=O)ON[C@@H](CSc1cccc(F)c1[N+](=O)[O-])C(=O)O>>CC(C)(C)C(=O)ON[C@@H](CSc1cccc(F)c1N)C(=O)O,[Pd],CCO,,,,test
US06518257B1,CI.OCc1cc(Br)ccc1F>>COCc1cc(Br)ccc1F,,C1CCOC1,,O,[H-].[Na+],test
US20110183938A1,O=C(Cl)OCc1ccccc1.Oc1cncc2[nH]c3ncc(Br)cc3c12>>O=C(OCc1ccccc1)n1c2cncc(O)c2c2cc(Br)cnc21,,CN(C)C=O,,[H-].[Na+],,test
US05025031,COc1ccc(Br)cc1.Cc1ncc[nH]1>>Cc1nccn1-c1ccc(O)cc1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20070149663A1,CC(C)C(=O)OC(=O)C(C)C.CC(C)NC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>CC(C)NC(=O)c1cc(NC(=O)C(C)C)cc(NC(=O)C(C)C)c1,[Pd],CN1CCCC1=O,,,,test
US20030004166A1,COC(C)c1nc(Cl)nc(N2CC(C)NC(C)C2)n1>>CC1CN(c2nc(Cl)nc(C(C)O)n2)CC(C)N1,,ClCCl,,BrB(Br)Br,O,test
US20120101064A1,CC(C)(C)OC(=O)N1CCN(c2ccc3nc(C(=O)c4ccc(C#N)c(-c5cncc6ccccc56)c4)[nH]c3n2)CC1>>N#Cc1ccc(C(=O)c2nc3ccc(N4CCNCC4)nc3[nH]2)cc1-c1cncc2ccccc12,,CCOCC,Cl,,,test
US20080139539A1,NN.O=C(CCl)N(CCN1C(=O)c2ccccc2C1=O)CCN1C(=O)c2ccccc2C1=O>>O=C1CNCCN1CCN1C(=O)c2ccccc2C1=O,,CCO,,O,,test
US20080269244A1,CC(C)(C)OC(=O)N1CCC(O)CC1.Cc1nc(O)ccc1[N+](=O)[O-]>>Cc1nc(OC2CCN(C(=O)OC(C)(C)C)CC2)ccc1[N+](=O)[O-],,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05985849,CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@H](n2cc(C(c3ccccc3)c3ccccc3)c(=S)[nH]c2=O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C>>O=c1[nH]c(=S)c(C(c2ccccc2)c2ccccc2)cn1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20060241115A1,C1CCNCC1.COc1cc2c(Cl)ccnc2cc1OCCCCl>>COc1cc2c(Cl)ccnc2cc1OCCCN1CCCCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110160199A1,COc1cccc(N)c1.O=C(Cl)CCl>>COc1cccc(NC(=O)CCl)c1,,ClCCl,,c1ccncc1,,test
US20070232645A1,CNOC.Cc1ccc(Sc2ccccc2)c(Nc2c(C(=O)O)cnc3nc(C)ccc23)c1>>CON(C)C(=O)c1cnc2nc(C)ccc2c1Nc1cc(C)ccc1Sc1ccccc1,,CN(C)C=O,,Cl,O=C(n1ccnc1)n1ccnc1,test
US05834493,ClCCCC1OCCO1.NOc1ccccc1>>ClCCCC=NOc1ccccc1,,C1CCOC1,,Cl,,test
US20060178373A1,CC(C)(C)NCC(O)COc1ccc2oc(-c3ccc(OCc4ccccc4)c(OCc4ccccc4)c3)cc(=O)c2c1>>CC(C)(C)NCC(O)COc1ccc2oc(-c3ccc(O)c(O)c3)cc(=O)c2c1,[Pd],CO,,,,test
US20090042929A1,Cc1c(C(=O)CS(=O)Cc2ccc(Cl)cc2)sc2ccc(Cl)cc12.O=C(OO)c1cccc(Cl)c1>>Cc1c(C(=O)CS(=O)(=O)Cc2ccc(Cl)cc2)sc2ccc(Cl)cc12,,ClCCl,,,,test
US20160108016A1,CC1=CC[C@H]2[C@@H](C1)c1c(O)cc(C(C)(C)C(=O)O)cc1OC2(C)C.CCCCCN>>CCCCCNC(=O)C(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21,,ClCCl,,CCN(CC)CC,,test
US20100233116A1,Cc1nc(N2CCN(Cc3ccccc3)C2=O)sc1C(=O)O.NCc1ccccc1>>Cc1nc(N2CCN(Cc3ccccc3)C2=O)sc1C(=O)NCc1ccccc1,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US04220774,CC[C@]12CCCN3CC[C@]4(C(=C(C(=O)OC)C1)Nc1ccccc14)[C@@H]32.CI>>CCC12CCCN3CCC4(C(=C(C(=O)OC)C1)N(C)c1ccccc14)C32,,CCOCC,CN(C)C=O,O,[H-].[Na+],test
US20090124596A1,CN.O=C(N[C@H]1CC[C@@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(-c4ccc(OCCCl)cc4)c3)c2=O)CC1)c1cn2cc(F)ccc2n1>>CNCCOc1ccc(-c2cccc(-n3c(=O)n([C@@H]4CC[C@H](NC(=O)c5cn6cc(F)ccc6n5)CC4)c(=O)c4cc(F)cnc43)c2)cc1,,CC#N,,[I-].[K+],,test
US20150038528A1,CCCCOC(=O)c1nc(C#N)c2ccc(Oc3ccccc3)cc2c1O.COC(=O)C(C)(C)CN>>COC(=O)C(C)(C)CNC(=O)c1nc(C#N)c2ccc(Oc3ccccc3)cc2c1O,,CCO,,,,test
US20090054405A1,CC(=O)Nc1nc2ccc(B3OC(C)(C)C(C)(C)O3)cc2s1.Nc1cc(Br)cnc1Cl>>CC(=O)Nc1nc2ccc(-c3cnc(Cl)c(N)c3)cc2s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US20100004245A1,CCOC(=O)c1cncc(-c2ccc(N3CCC(O)CC3)nn2)c1.Oc1ccccc1I>>CCOC(=O)c1cncc(-c2ccc(N3CCC(Oc4ccccc4I)CC3)nn2)c1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080269192A1,CC(C)[C@H]1COCc2nc3c(N)nc4ccc(OCc5ccccc5)cc4c3n21>>CC(C)[C@H]1COCc2nc3c(N)nc4ccc(O)cc4c3n21,[Pd],CCO,,ClC(Cl)Cl,,test
US20130029961A1,CCOC(=O)C(C(=O)OCC)c1ccc([N+](=O)[O-])cn1.CI>>CCOC(=O)C(C)(C(=O)OCC)c1ccc([N+](=O)[O-])cn1,,CN(C)C=O,,O,[H-].[Na+],test
US20140288109A1,COC(=O)C1CN(C(=O)OC(C)(C)C)CCO1.C[Si](C)(C)CCOCCl>>COC(=O)C1(COCC[Si](C)(C)C)CN(C(=O)OC(C)(C)C)CCO1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20130261077A1,COc1ccc([C@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](O[C@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H]3OC(C)=O)[C@@H]2O)cc1O[Si](C)(C)C(C)(C)C>>COc1ccc([C@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](O[C@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H]3OC(C)=O)[C@@H]2O)cc1O,,C1CCOC1,,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20150005311A1,Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)N(CCCCCC(=O)O)CCC3)cc1.N#CCCN>>Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)N(CCCCCC(=O)NCCC#N)CCC3)cc1,,ClCCl,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110263610A1,C[C@@H]1CN(Cc2cn(C3CCCCO3)nc2C2=CCN(C(=O)OC(C)(C)C)CC2)CCN1c1ccc(C(F)(F)F)cn1>>C[C@@H]1CN(Cc2c[nH]nc2C2=CCNCC2)CCN1c1ccc(C(F)(F)F)cn1,,CC(C)O,CO,Cl,,test
US06403791B1,COc1ccc(Br)c2oc(N3CCCCC3)nc12>>Oc1ccc(Br)c2oc(N3CCCCC3)nc12,,CCOCC,,,,test
US20060058324A1,CC(=O)OC(C)=O.Nc1ncnc2c1c(-c1cccc(OCc3ccccc3)c1)cn2[C@H]1CC[C@@H](N)CC1>>CC(=O)NC1CCC(n2cc(-c3cccc(OCc4ccccc4)c3)c3c(N)ncnc32)CC1,,C1CCOC1,,,,test
US20060030583A1,CC(=O)Nc1ncc(Br)cc1C#C[Si](C)(C)C>>Brc1cnc2[nH]ccc2c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090105214A1,CC(C)(C)OC(=O)n1ccc(N)n1.CC(C)Oc1cc(Oc2ccc3c(c2)OCCN(C)C3=O)cc(C(=O)O)c1>>CC(C)Oc1cc(Oc2ccc3c(c2)OCCN(C)C3=O)cc(C(=O)Nc2ccn(C(=O)OC(C)(C)C)n2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030105142A1,Cc1ccc(N)cc1NC(=O)c1ccc2ncccc2c1.O=C(Cl)c1ccc(C(F)(F)F)cc1>>Cc1ccc(NC(=O)c2ccc(C(F)(F)F)cc2)cc1NC(=O)c1ccc2ncccc2c1,,CCN(CC)CC,,,,test
US20140314669A1,COC(=O)CC(NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1cncc(-c2ccccc2O)c1.Cc1ccc(S(=O)(=O)OCCOS(=O)(=O)c2ccc(C)cc2)cc1>>COC(=O)CC(NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1cncc(-c2ccccc2OCCOS(=O)(=O)c2ccc(C)cc2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05736548,CC(C)(C)n1ncc(C#N)c1N.OO>>CC(C)(C)n1ncc(C(N)=O)c1N,,O,,[K+].[OH-],,test
US20050191238A1,CC(C)(C)c1ccc(C(CO)OC2CCCCO2)cc1.Clc1ncnc2ccccc12>>CC(C)(C)c1ccc(C(COc2ncnc3ccccc23)OC2CCCCO2)cc1,,C1CCOC1,,O,[H-].[Na+],test
US20090170828A1,CC(=O)OCc1nnc(-c2ccc(N3CC(Cc4ccccc4C(F)(F)F)C3)nn2)o1>>OCc1nnc(-c2ccc(N3CC(Cc4ccccc4C(F)(F)F)C3)nn2)o1,,CO,,NN,O,test
US20120264737A1,COC(=O)c1ccc(C)c(N)c1.NN>>Cc1ccc(C(=O)NN)cc1N,,CCO,,O,,test
US20070099901A1,CCCc1nc2c(N)nc3cc(-c4ccccc4)ccc3c2n1CCCC(C)=NOC>>CCCc1nc2c(N)nc3cc(-c4ccccc4)ccc3c2n1CCCC(C)NOC,,CC(=O)O,CCO,[BH3-]C#N.[Na+],,test
US04224254,OCc1ccc(CO)cc1>>O=Cc1ccc(C=O)cc1,,C1COCCO1,,,,test
US20020055630A1,O=C(N[C@@H](CO)C(=O)O)c1cccc2c1NC1CCCC21>>O=C1N[C@@H](CO)C(=O)N2c3c1cccc3C1CCCC12,,CC(=O)O,,,,test
US20100234395A1,COc1ccc(C(=O)C(CC(=O)C2CCN(C(=O)OCc3ccccc3)CC2)c2ccc(OC)cc2)cc1>>COc1ccc(-c2cc(C3CCNCC3)oc2-c2ccc(OC)cc2)cc1,,O=S(=O)(O)O,,O=C([O-])O.[Na+],,test
US20060173018A1,O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OCC1CCOC1.c1ccc(CN2CCNCC2)cc1>>O=C(OCC1CCOC1)N1CCN(Cc2ccccc2)CC1,,ClCCl,,CCN(CC)CC,c1ccncc1,test
US20070155805A1,CNOC.Cc1c(C(=O)O)sc2cc(C(F)(F)F)ccc12>>CON(C)C(=O)c1sc2cc(C(F)(F)F)ccc2c1C,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20020077329A1,Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(-n3c(C(C)O)nc4cc(C(F)(F)F)c(Cl)cc43)cc2)cc1>>CC(=O)c1nc2cc(C(F)(F)F)c(Cl)cc2n1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1,O=[Mn]=O,ClCCl,,,,test
US08557858B2,Cn1cc(-c2ccc(S(=O)(=O)n3ccc(/C=C/C(=O)Nc4ccccc4N)c3)cc2)cn1.O=S(=O)(O)c1ccc2ccccc2c1>>Cn1cc(-c2ccc(S(=O)(=O)n3ccc(/C=C/C(=O)Nc4ccccc4N)c3)cc2)cn1.O=S(=O)(O)c1ccc2ccccc2c1,,CC(C)O,,,,test
US20010014688A1,C#CCN1CCC(C(=O)NO)(S(=O)(=O)c2ccc(Oc3ccccc3)cc2)CC1.CCOC1(O[Si](C)(C)C)CC1.Cl>>Cl.O=C(NO)C1(S(=O)(=O)c2ccc(Oc3ccccc3)cc2)CCN(C2CC2)CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20080142790A1,CCCCCCCCS.N#Cc1ccc([N+](=O)[O-])cc1C#N>>CCCCCCCCSc1ccc(C#N)c(C#N)c1,,CC(=O)N(C)C,,Cl,O=C([O-])[O-].[K+].[K+],test
US07078414B2,CCOC(=O)c1ccn(-c2ccc3ccccc3n2)c1C>>Cc1c(C(=O)O)ccn1-c1ccc2ccccc2n1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20100240717A1,CC(=O)C(=CO)CC(C)C.O=C(Cl)C(=O)Cl>>CC(=O)C(=CCl)CC(C)C,,ClC(Cl)Cl,,[Na+].[OH-],,test
US04985427,CNC(=O)NNc1ccccc1.COC(=O)CBr>>CNC(=O)NN(CC(=O)OC)c1ccccc1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US06482921B1,C[C@H](NCOCc1ccccc1)[C@H](NC(=O)OC(C)(C)C)C(=O)O>>CN[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)O,[Pd],CO,,,,test
US20050171109A1,COc1c(F)ccc2c1C(C)(C)CC(O)(C(F)(F)F)C2Nc1cccc2[nH]ncc12>>CC1(C)CC(O)(C(F)(F)F)C(Nc2cccc3[nH]ncc23)c2ccc(F)c(O)c21,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US04666510,CCCC(=O)C1=C(O)CC(c2c(C)cc(C)cc2C)CC1=O.COC(Cl)Cl>>CCCC(=O)C1=C(O)CC(c2c(C)cc(C)c(C=O)c2C)CC1=O,Cl[Ti](Cl)(Cl)Cl,CC(Cl)Cl,,,,test
US05977105,COc1cccc(-c2ccc(OC(C)(C)C)cc2)c1>>COc1cccc(-c2ccc(O)cc2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120040983A1,CC(O)C(F)(F)F.Clc1nncc2cc(Br)ccc12>>CC(Oc1nncc2cc(Br)ccc12)C(F)(F)F,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20160264554A1,O=C(NC12CC3CC(C1)CC(NC(=O)OCc1ccccc1)(C3)C2)OCc1ccccc1>>NC12CC3CC(C1)CC(N)(C3)C2,[Pd],CCO,,,,test
US05919434,CCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCCCC(=O)O.O=C(Cl)C(=O)Cl>>CCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCCCC(=O)Cl,,C1CCOC1,,,,test
US20060252758A1,CCCCCN1C(=O)C(=O)c2cccnc21.Oc1ccc2c(c1)OCO2>>CCCCCN1C(=O)C(O)(c2cc3c(cc2O)OCO3)c2cccnc21,,C1CCOC1,ClCCl,CC(C)[Mg]Cl,,test
US20120165343A1,CCCC(O)c1ccc(C(=O)OCC)cc1.CS(=O)(=O)Cl>>CCCC(OS(C)(=O)=O)c1ccc(C(=O)OCC)cc1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20140371199A1,CC(=O)Cl.CN(C(=O)OC(C)(C)C)C1CCN(C(=O)c2ccc(Br)cc2N)CC1>>CC(=O)Nc1cc(Br)ccc1C(=O)N1CCC(N(C)C(=O)OC(C)(C)C)CC1,,ClCCl,,CCN(CC)CC,O,test
US20150133432A1,CCNC(=O)N1CC(C)(C)N(Cc2cc(-c3ccc(OCOC)cc3)nc3c2c(C)nn3C2CCCCO2)CC1(C)C>>CCNC(=O)N1CC(C)(C)N(Cc2cc(-c3ccc(O)cc3)nc3[nH]nc(C)c23)CC1(C)C,,C1COCCO1,,Cl,,test
US20050277674A1,C1=C(c2c[nH]c3ccccc23)CCNC1.CN(C)C1(c2ccccc2)CCC(=O)CC1>>CN(C)C1(c2ccccc2)CCC(N2CC=C(c3c[nH]c4ccccc34)CC2)CC1,,ClCCCl,,CC(=O)O,,test
US20140371227A1,COC(=O)CBr.Cc1ccnc2[nH]c(=O)c3cccn3c12>>COC(=O)Cn1c(=O)c2cccn2c2c(C)ccnc21,,CN(C)C=O,,[H-].[Na+],,test
US20140371212A1,CC(O)(F)F.CCOC(=O)c1ncc(F)cc1F>>CCOC(=O)c1ncc(OCC(F)F)cc1F,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20050215602A1,C#CCBr.FC(F)(F)C1CCNCC1>>C#CCN1CCC(C(F)(F)F)CC1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20080221188A1,CC(C)(C#N)c1ccc(Br)cc1.CON(C)C(C)=O>>CC(=O)c1ccc(C(C)(C)C#N)cc1,,C1CCOC1,,[Li]CCCC,,test
US20020147203A1,Cc1c(CO)ccnc1Cl.O=P(Cl)(Cl)Cl>>Cc1c(CCl)ccnc1Cl,,ClCCl,,CN(C)C=O,,test
US20090291977A1,Cc1nc2c(N)cc(C(=O)OC(C)C)cn2c1C.ClC1COCc2ccccc21>>Cc1nc2c(NC3COCc4ccccc43)cc(C(=O)OC(C)C)cn2c1C,,CC(C)O,,[I-].[K+],O=C([O-])O.[Na+],test
US20150336942A1,Nc1ncc(Br)cc1-c1nnc(C2CC2)o1.OB(O)c1cccc(CN2CCOCC2)c1>>Nc1ncc(-c2cccc(CN3CCOCC3)c2)cc1-c1nnc(C2CC2)o1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US05952266,O=C(O)c1ccc2c(c1)C1(CCS2(=O)=O)OCCO1.O=C1CCCC(=O)C1>>O=C1C=C(OC(=O)c2ccc3c(c2)C2(CCS3(=O)=O)OCCO2)CCC1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20090156616A1,CCCS(=O)(=O)Oc1ccc(-c2c(C)c(C(=O)NC3CCCCC3)nn2-c2ccc(Cl)cc2Cl)cc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCCS(=O)(=O)Oc1ccc(-c2c(C)c(C(=S)NC3CCCCC3)nn2-c2ccc(Cl)cc2Cl)cc1,,Cc1ccccc1,,,,test
US20100317657A1,CC=O.Cc1nn(C)cc1-n1c(=O)n(C)c2cnc3ccc(-c4cncc(N)c4)cc3c21>>CCNc1cncc(-c2ccc3ncc4c(c3c2)n(-c2cn(C)nc2C)c(=O)n4C)c1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20050070583A1,COC(=O)COc1ccc(SCC=C(c2ccc(F)cc2)c2ccc(F)cc2)cc1C>>Cc1cc(SCC=C(c2ccc(F)cc2)c2ccc(F)cc2)ccc1OCC(=O)O,,CCO,,[Na+].[OH-],,test
US20150038528A1,CC(C)(C)OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4c(F)cccc4F)ccc3c2O)CCC1>>N#Cc1nc(C(=O)NCC2(C(=O)O)CCC2)c(O)c2ccc(Oc3c(F)cccc3F)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070249659A1,CCOC(=O)CCC(=O)C(C)n1cc([N+](=O)[O-])ccc1=NS(=O)(=O)c1ccc(C)cc1>>CCOC(=O)CCc1nc2ccc([N+](=O)[O-])cn2c1C,,ClCCl,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US04824834,O=[N+]([O-])O.Oc1ncnc2c(-c3ccccc3)cnn12>>O=[N+]([O-])c1ccc(-c2cnn3c(O)ncnc23)cc1,,O,,CC(=O)O,O=S(=O)(O)O,test
US20120142625A1,CC(C)(C)c1ccc(N=C=O)cc1.CN(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21)C1CC(CN)C1>>CN(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21)C1CC(CNC(=O)Nc2ccc(C(C)(C)C)cc2)C1,,ClCCl,,,,test
US04889553,BrBr.c1ccc(CSc2ncn(-c3ccccc3)n2)cc1>>Brc1nc(SCc2ccccc2)nn1-c1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US20140364432A1,Cc1ccc(-c2cnn(C)c2)c(C(=O)N2CCC[C@@H](C)[C@H]2CN)c1.Clc1nc2ccccc2o1>>Cc1ccc(-c2cnn(C)c2)c(C(=O)N2CCC[C@@H](C)[C@H]2CNc2nc3ccccc3o2)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US06114390,CN(Cc1ccccc1)Cc1ccc(C#N)cc1>>CN(Cc1ccccc1)Cc1ccc(CN)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150376208A1,C[C@@H]1CN(C(=O)OC(C)(C)C)c2c(sc3ccc4nc(Cl)ccc4c23)C(=O)N1C(=O)OC(C)(C)C>>C[C@@H]1CNc2c(sc3ccc4nc(Cl)ccc4c23)C(=O)N1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110152240A1,O=C1CNC(=O)N1.O=Cc1cnn2c(NC3CC3)cc(NC3CCCC3)nc12>>O=C1NC(=O)/C(=C/c2cnn3c(NC4CC4)cc(NC4CCCC4)nc23)N1,,CCO,,C1CCNCC1,,test
US20100292188A1,O=C(O)CC(F)(F)F.c1cc(-c2nc3c(s2)CNCC3)ccc1O[C@@H]1C[C@@H](N2CCCCC2)C1>>O=C(CC(F)(F)F)N1CCc2nc(-c3ccc(O[C@@H]4C[C@@H](N5CCCCC5)C4)cc3)sc2C1,,CN(C)C=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20020183361A1,CCC(CC)[C@H](NS(=O)(=O)c1ccc(Cl)s1)C(=O)O>>CCC(CC)[C@@H](CO)NS(=O)(=O)c1ccc(Cl)s1,,C1CCOC1,,,,test
US20160200730A1,NCCCn1nc(-c2ccc(Oc3c(F)c(F)cc(F)c3F)cc2F)c2c(N)ncnc21.O=C1C=CC(=O)O1>>Nc1ncnc2c1c(-c1ccc(Oc3c(F)c(F)cc(F)c3F)cc1F)nn2CCCNC(=O)/C=C/C(=O)O,,ClCCl,,CCN(CC)CC,,test
US20090176836A1,CC(C)(C)OC(=O)NC1(Cc2ccccc2)CCOC1=O>>CC(C)(C)OC(=O)NC1(Cc2ccccc2)CCOC1O,,C1CCOC1,,CC(C)C[AlH]CC(C)C,,test
US05919799,NNC(=O)c1cccnc1.O=Cc1c(-c2ccc([N+](=O)[O-])cc2)nc2sc3c(n12)CCCC3>>O=C(NN=Cc1c(-c2ccc([N+](=O)[O-])cc2)nc2sc3c(n12)CCCC3)c1cccnc1,,CO,,[K+].[OH-],,test
US20140088075A1,CCOC(=O)CC(=O)CC(=O)OCC.CCOC(OCC)OCC.N>>CCOC(=O)c1cnc(O)cc1O,,ClCCl,,CC(=O)OC(C)=O,,test
US20020019429A1,COC1C=C(c2ccccc2)C(OC)O1>>COC1CC(c2ccccc2)C(OC)O1,[Rh],CCOC(C)=O,,,,test
US20040110767A1,Cc1cc(C=O)ccc1OC1CCCCO1.Nc1ccc(OCCN2CCCC2)cc1>>Cc1cc(CNc2ccc(OCCN3CCCC3)cc2)ccc1OC1CCCCO1,,ClCCl,,O=S(=O)([O-])[O-].[Mg+2],,test
US20140275152A1,CC(=O)N1CCC(c2ccccc2)=C(CCl)C1.O=Cc1c(O)cccc1O>>CC(=O)N1CCC(c2ccccc2)=C(COc2cccc(O)c2C=O)C1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20060223829A1,CCOC(=O)C1(N2CCNCC2)CCC1.O=S(=O)(Cl)c1ccccc1Cl>>CCOC(=O)C1(N2CCN(S(=O)(=O)c3ccccc3Cl)CC2)CCC1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US05112988,COC(=O)Cc1ccccc1N(C)C(=O)OC(C)(C)C>>CN(C(=O)OC(C)(C)C)c1ccccc1CC(=O)O,,CCO,,[Na+].[OH-],,test
US20090306066A1,Cc1nc(NNC(=O)[C@H](CC2CCCC2)CN(C=O)OCc2ccccc2)c(F)c(N2CCN(C)C[C@@H]2C)n1>>Cc1nc(NNC(=O)[C@H](CC2CCCC2)CN(O)C=O)c(F)c(N2CCN(C)C[C@@H]2C)n1,,CO,,,,test
US20040122001A1,C=CCN1CCCc2cc(C(=O)O)ccc21.NCCO>>C=CCN1CCCc2cc(C(=O)NCCO)ccc21,,C1CCOC1,,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US20050171115A1,CC(C)(C)OC(=O)N1CCN(C(=O)C(c2ccc(OCc3ccccc3)c(OC(F)(F)F)c2)C2(O)CCCCC2)CC1>>CC(C)(C)OC(=O)N1CCN(C(=O)C(c2ccc(O)c(OC(F)(F)F)c2)C2(O)CCCCC2)CC1,[Pd],CO,,O=C[O-].[NH4+],,test
US20010037037A1,CCCCCCCCCCCCc1ccc(S(=O)(=O)Cl)cc1.COc1ccc(C(C#N)=NO)cc1OC>>CCCCCCCCCCCCc1ccc(S(=O)(=O)ON=C(C#N)c2ccc(OC)c(OC)c2)cc1,,C1CCOC1,,CCN(CC)CC,O,test
US20160016908A1,CC(=O)N1c2ccccc2[C@H](NC(=O)OCc2ccccc2)[C@@H](C)[C@@H]1CO[Si](C)(C)C(C)(C)C>>CC(=O)N1c2ccccc2[C@H](N)[C@@H](C)[C@@H]1CO[Si](C)(C)C(C)(C)C,[Pd],CO,,,,test
US20100197655A1,CC(C)(C)OC(=O)N(c1cscn1)S(=O)(=O)c1cc(F)c(Oc2ccc(Cl)cc2-c2ccnc(CN3CCC3)c2)cc1F>>O=S(=O)(Nc1cscn1)c1cc(F)c(Oc2ccc(Cl)cc2-c2ccnc(CN3CCC3)c2)cc1F,,C1COCCO1,ClCCl,Cl,,test
US20080183282A1,CC(=O)N[C@@H]1[C@@H](O[C@@H]2O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H](OS(=O)(=O)O)O[C@H]1O.CCO.ClC(Cl)Cl.ClCCCl.On1nnc2ccccc21>>CCN(CC)CCOc1ccc(Cc2ccccc2)cc1.Cl,,CO,ClC(Cl)Cl,O,,test
US20160166560A1,CN(C(=O)n1cnc(-c2cccc(NC(N)=O)c2)c1)C1CCN(Cc2ccccc2)CC1.Cl>>CN(C(=O)n1cnc(-c2cccc(NC(N)=O)c2)c1)C1CCN(Cc2ccccc2)CC1.Cl,,CCOC(C)=O,,CO,,test
US20080269192A1,CC(C)(C)[Si](C)(C)Cl.Cc1nc(Cl)c([N+](=O)[O-])c(N[C@@H](C)CO)c1C>>Cc1nc(Cl)c([N+](=O)[O-])c(N[C@@H](C)CO[Si](C)(C)C(C)(C)C)c1C,CN(C)c1ccncc1,c1ccncc1,,,,test
US20140323475A1,CC(C)N(C(=O)c1nccc2c1CCCN2Cc1cc(Cl)ccc1OCc1ccc(F)cc1F)C(C)C>>O=Cc1nccc2c1CCCN2Cc1cc(Cl)ccc1OCc1ccc(F)cc1F,,C1CCOC1,,CC(C)C[AlH]CC(C)C,,test
US20050250782A1,Nc1ccc(Br)cc1F.O=C(O)c1cnc(Cl)c(F)c1Cl>>O=C(O)c1cnc(Cl)c(F)c1Nc1ccc(Br)cc1F,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20100331326A1,CC(=O)Nc1ccc(Br)cn1.Cc1ccncc1N1CCNC1=O>>CC(=O)Nc1ccc(N2CCN(c3cnccc3C)C2=O)cn1,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20080167217A1,CC(=O)Oc1ccc(OC(C)=O)cc1.O=C1CCCCCCCCC(=O)O1>>O=C(O)CCCCCCCCC(=O)c1cc(O)ccc1O,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20010011090A1,CCN.Cn1nc(C(F)(F)F)cc1-c1ccc(C(=O)Cl)s1>>CCNC(=O)c1ccc(-c2cc(C(F)(F)F)nn2C)s1,,O,,C1CCOC1,,test
US20110046127A1,CCOC(=O)c1cccc(NC(=O)c2cnc3c(C)cc(NCc4ccc(OC)cc4)nn23)c1.CNC>>COc1ccc(CNc2cc(C)c3ncc(C(=O)Nc4cccc(C(=O)N(C)C)c4)n3n2)cc1,,C1CCOC1,ClCCl,C[Al](C)C,,test
US20110269712A1,CCOC(=O)C1CCN(C(=O)Cn2nc(C(F)(F)F)cc2C)CC1>>Cc1cc(C(F)(F)F)nn1CC(=O)N1CCC(C(=O)O)CC1,,CO,,Cl,[Na+].[OH-],test
US20040220247A1,COc1ccc(N)cc1.O=C(O)Cc1ccc([N+](=O)[O-])cc1>>COc1ccc(NC(=O)Cc2ccc([N+](=O)[O-])cc2)cc1,,c1ccncc1,,CCN=C=NCCCN(C)C,Cl,test
US20160130268A1,CC(C)(C)OC(=O)Nc1cccc(CCI)n1.COc1cc(OC)cc(-c2cc3cnc(SC)nc3[nH]c2=O)c1>>COc1cc(OC)cc(-c2cc3cnc(SC)nc3n(CCc3cccc(NC(=O)OC(C)(C)C)n3)c2=O)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060211739A1,Clc1cccc(-c2nnn[nH]2)c1Cl.Clc1cccc(Cl)c1CBr>>Clc1cccc(-c2nnnn2Cc2c(Cl)cccc2Cl)c1Cl,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20160067208A1,CC(C)=CCCC(C)=CCCC(C)=CCCC(=O)OCC(O)CO.O>>CC(C)=CCCC(C)=CCCC(C)=CCCC(=O)OCC(O)CO.O,,O,,,,test
US20070021443A1,N[C@@H]1CCOc2c(F)cccc21.O=[N+]([O-])c1cnc(Cl)nc1Cl.O=[N+]([O-])c1cnc(Cl)nc1N[C@@H]1CCOc2c(F)cccc21>>O=[N+]([O-])c1cnc(-n2cnc3ccccc32)nc1N[C@@H]1CCOc2c(F)cccc21,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20120142717A1,COC(=O)C(C=O)Cc1cnc(OC)nc1.N=C(N)OCCc1ccc(Oc2ccc(F)cc2)cc1>>COc1ncc(Cc2c[nH]c(OCCc3ccc(Oc4ccc(F)cc4)cc3)nc2=O)cn1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20030171377A1,CC(=O)Cl.COC(=O)C(Cc1ccc(OC(C)=O)cc1)n1c(C)ccc1C>>COC(=O)[C@H](Cc1ccc(OC(C)=O)cc1)n1c(C)cc(C(C)=O)c1C,,ClCCl,,O=S(=O)(O)C(F)(F)F,,test
US04644071,CCCc1ccccc1OCCCCCOc1coc(CO)cc1=O>>CCCc1ccccc1OCCCCCOc1coc(C=O)cc1=O,,CCOCC,ClCCl,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US05965589,CC(C)Oc1ccc(C=CC=O)cc1.O=C1CSC(=O)N1>>CC(C)Oc1ccc(CCCC2SC(=O)NC2=O)cc1,,CC(=O)O,,C1CCNCC1,,test
US04929741,C#CC(=O)OC.CN(C)c1ccc(C=O)cc1>>COC(=O)C#CC(O)c1ccc(N(C)C)cc1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20050288314A1,N#Cc1c(F)cccc1I.OB(O)c1ccsc1>>N#Cc1c(F)cccc1-c1ccsc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US06300353B1,C[C@@H](OC1CCCCO1)C(=O)c1cc(F)ccc1F.C[S+](C)(C)=O>>C[C@@H](OC1CCCCO1)C1(c2cc(F)ccc2F)CO1,,CS(C)=O,,[H-].[Na+],,test
US20110275611A1,N#Cc1ccc(-c2cc(N3CCC[C@@H](N4CCOC4=O)C3)nc(N)n2)cc1F.NN>>Nc1nc(-c2ccc3c(N)n[nH]c3c2)cc(N2CCC[C@@H](N3CCOC3=O)C2)n1,,CCO,,O,,test
US20090143353A1,CNCCO.Cc1c(-c2ccccc2)c(F)c2oc(Cl)nc2c1C#N>>Cc1c(-c2ccccc2)c(F)c2oc(N(C)CCO)nc2c1C#N,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090030009A1,CN1CCN(Cc2ccc(NC(=O)c3nsc4cc(O)ccc34)cc2C(F)(F)F)CC1.Nc1nc(Cl)cc(Cl)n1>>CN1CCN(Cc2ccc(NC(=O)c3nsc4cc(Oc5cc(Cl)nc(N)n5)ccc34)cc2C(F)(F)F)CC1,,CN1CCCC1=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140127239A1,C=CCOC(=O)C(=O)C(NC(=O)C(C)NNc1ccc(COC(=O)N2c3cc(O[Si](C(C)C)(C(C)C)C(C)C)c(OC)cc3C(=O)N3C=C(C)C[C@H]3[C@@H]2O)cc1)C(C)C.CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F>>C=CCOC(=O)C(=O)C(NC(=O)C(C)NNc1ccc(COC(=O)N2c3cc(O[Si](C(C)C)(C(C)C)C(C)C)c(OC)cc3C(=O)N3C=C(C)C[C@H]3[C@@H]2O[Si](C)(C)C(C)(C)C)cc1)C(C)C,,ClCCl,,Cc1cccc(C)n1,,test
US20160272634A1,ICCCCI.O=C1CS(=O)(=O)c2ccc(Br)cc21>>O=C1c2cc(Br)ccc2S(=O)(=O)C12CCCC2,,C1CCOC1,,,,test
US05371062,COC(=O)c1c(O)cccc1C=Cc1ccccc1.COc1cc(OC)nc(S(C)(=O)=O)n1>>COC(=O)c1c(C=Cc2ccccc2)cccc1Oc1nc(OC)cc(OC)n1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20030055085A1,NC(=O)c1cc(Br)cc(I)c1.O=C(CBr)c1ccccn1>>Brc1cc(I)cc(-c2nc(-c3ccccn3)co2)c1,,Cc1ccccc1,,,,test
US20060135501A1,CN(C)c1ccc(NC(=S)N2CCC(c3nc(C(=O)O)cs3)CC2)cc1.COc1ccc(C(N)=O)cc1N>>COc1ccc(C(N)=O)cc1NC(=O)c1csc(C2CCN(C(=S)Nc3ccc(N(C)C)cc3)CC2)n1,,CCN(C(C)C)C(C)C,CN(C)C=O,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20040006141A1,CS(=O)(=O)Cl.O=C(NCCCc1ccc(CO)cc1)c1ccc(-c2ccccn2)cc1>>O=C(NCCCc1ccc(CCl)cc1)c1ccc(-c2ccccn2)cc1,,ClCCl,,CCN(CC)CC,,test
US08569494B2,Brc1ccc(-c2nncn2C2CCCCO2)cc1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(c2ccc(-c3nncn3C3CCCCO3)cc2)OC1(C)C,,CN(C)C=O,,CC(=O)[O-].[K+],,test
US20060281779A1,CCOC(=O)c1cn(C(C)(C)C)c2nc(Cl)c(F)cc2c1=O.F[C@@H]1CNC[C@@H]1CNC1CC1>>CC(C)(C)n1cc(C(=O)O)c(=O)c2cc(F)c(N3C[C@H](CNC4CC4)[C@H](F)C3)nc21,,CC#N,,C1CCC2=NCCCN2CC1,,test
US03968228,Cn1c(CO)nc([N+](=O)[O-])c1C#N.O=S(Cl)Cl>>Cn1c(CCl)nc([N+](=O)[O-])c1C#N,,c1ccccc1,,,,test
US20150133428A1,CC1CC(C(=O)O)C1.NC(=O)c1c(-c2ccc(F)c(Cl)c2)nn2c1CNCC2.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC1CC(NC(=O)N2CCn3nc(-c4ccc(F)c(Cl)c4)c(C(N)=O)c3C2)C1,,C1CCOC1,,Cc1ccccc1,,test
US05451700,CC(C)N(C(=O)c1ccc(O)cc1O)c1ccccc1.N#Cc1ccc(OCCCCCBr)cc1>>CC(C)N(C(=O)c1ccc(OCCCCCOc2ccc(C#N)cc2)cc1O)c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130018049A1,CCOC(=O)c1c(F)nc(C)c(C(=O)OC)c1-c1ccc(C)cc1.NC1CCCCC1>>CCOC(=O)c1c(NC2CCCCC2)nc(C)c(C(=O)OC)c1-c1ccc(C)cc1,,ClCCCl,,CCN(CC)CC,,test
US20140371199A1,CCOC(=O)c1ccc(-c2ccn3nccc3n2)cc1.O=C1CCC(=O)N1Br>>CCOC(=O)c1ccc(-c2ccn3ncc(Br)c3n2)cc1,,CC#N,ClCCl,,,test
US20110237584A1,Clc1nc2ccccc2nc1Cl.NS(=O)(=O)c1ccccc1F>>O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccccc1F,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080207654A1,CCCCc1nc(C)n(CC2CC2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nc(C)n(CC2CC2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US05025031,COc1ccccc1OCCO.NS(=O)(=O)Cl>>COc1ccccc1OCCOS(N)(=O)=O,,ClCCl,,C,,test
US20140315949A1,CC1COc2cc(C(=O)O)ccc21.Cc1cc(C)c(CN)c(O)n1>>Cc1cc(C)c(CNC(=O)c2ccc3c(c2)OCC3C)c(O)n1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130053366A1,C=Cc1cscc1C.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>Cc1ccc2c(c1)c1c(n2CCc2cscc2C)CCN(C)C1,,CN1CCCC1=O,O,[K+].[OH-],,test
US04822813,CC(=O)C(Cl)CCCl.OCCS>>ClCCC1=COCCS1,,Cc1ccccc1,,CCN(CC)CC,,test
US04486428,CC(=O)OC1(CCCO)Cc2ccc(OC(C)CCCc3ccccc3)cc2OC1(C)C.COc1cc(CNCCCNCCCCNCCCN)ccc1O.CS(=O)(=O)Cl>>CC(=O)OC1(CCCOS(C)(=O)=O)Cc2ccc(OC(C)CCCc3ccccc3)cc2OC1(C)C.COc1cc(CNCCCNCCCCNCCCN)ccc1O,,c1ccncc1,,,,test
US20140023611A1,CCN(CC)c1ccc(NC(=O)c2cccc(C(=O)N(C)CCO)c2)c(-c2cc(C(=O)N[C@H]3CCCc4ccccc43)ccn2)c1>>CCN(CC)c1ccc(NC(=O)c2cccc(C(=O)N(C)CC=O)c2)c(-c2cc(C(=O)N[C@H]3CCCc4ccccc43)ccn2)c1,,ClCCl,,CS(C)=O,O=C(Cl)C(=O)Cl,test
US20100029753A1,CC(C)(C)c1ccc(S(=O)(=O)Cl)cc1.CCOC(=O)c1sc2ncccc2c1N>>COC(=O)c1sc2ncccc2c1NS(=O)(=O)c1ccc(C(C)(C)C)cc1,,O,c1ccncc1,,,test
US20110301356A1,COC(OC)N(C)C.Nc1ccccc1Cl>>CN(C)C=Nc1ccccc1Cl,,Cc1ccccc1,,,,test
US20080167361A1,CCO.O=C(O)c1cc(Br)ccc1I>>CCOC(=O)c1cc(Br)ccc1I,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20100041658A1,CCc1ccc(Oc2ccc(N)cc2F)c(OC)c1.O=Cc1cccnc1>>CCc1ccc(Oc2ccc(NCc3cccnc3)cc2F)c(OC)c1,,CO,,[BH4-].[Na+],,test
US20070082912A1,CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(S(C)(=O)=O)ccc2O)c1.Clc1ccc(CBr)cc1>>CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(S(C)(=O)=O)ccc2OCc2ccc(Cl)cc2)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20160016948A1,COC1CCN(c2nccc(Nc3cc4c(ccn4CC(C)(C)C(=O)O)cn3)n2)CC1.[NH4+]>>COC1CCN(c2nccc(Nc3cc4c(ccn4CC(C)(C)C(N)=O)cn3)n2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04004912,C#CCN1CCC(O)N(c2nnc(C3CC3)s2)C1=O.O=C(OC(=O)c1ccccc1)c1ccccc1>>C#CCN1CCC(OC(=O)c2ccccc2)N(c2nnc(C3CC3)s2)C1=O,,c1ccccc1,,Cc1ccccc1S(=O)(=O)O,,test
US05705188,CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COC(=O)CCCCCCC/C=C\CCCCCCCC)OC(=O)NCCBr.CNCCO>>CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COC(=O)CCCCCCC/C=C\CCCCCCCC)OC(=O)NCCN(C)CCO,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,,test
US20100152257A1,CCOC(=O)Cc1ccc(OC)c(-c2ccc(-c3onc(C)c3NC(=O)OC(C)c3ccccc3Cl)cc2)c1>>COc1ccc(CC(=O)O)cc1-c1ccc(-c2onc(C)c2NC(=O)OC(C)c2ccccc2Cl)cc1,,CO,O,[Li+].[OH-],,test
US20150057265A1,C=Cc1cnc2c(C(=O)Nc3cnccc3N3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](C(F)(F)F)C3)c(NC(=O)OC(C)(C)C)oc2c1.O=[Os](=O)(=O)=O>>CC(C)(C)OC(=O)Nc1oc2cc(C=O)cnc2c1C(=O)Nc1cnccc1N1C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](C(F)(F)F)C1,O=[Os](=O)(=O)=O,O,,C1CCOC1,,test
US20100240671A1,CN1CCN(c2cc(-c3ccc4c(c3)CN(C(=O)Oc3ccc([N+](=O)[O-])cc3)CC4)nc(N)n2)CC1.c1ccc(C2CCNCC2)cc1>>CN1CCN(c2cc(-c3ccc4c(c3)CN(C(=O)N3CCC(c5ccccc5)CC3)CC4)nc(N)n2)CC1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US20080262042A1,CN(Cc1cn(S(=O)(=O)c2cccc(C(=O)NCCO)c2)c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C.Cl>>CNCc1cn(S(=O)(=O)c2cccc(C(=O)NCCO)c2)c(-c2cccnc2F)c1F.Cl,,CC(C)O,CCOC(C)=O,,,test
US20150011528A1,CCC(C(=O)OC)n1c(=NC(=O)c2ccc(C)cc2)sc2cc(CO)ccc21>>CCC(C(=O)O)n1c(=NC(=O)c2ccc(C)cc2)sc2cc(CO)ccc21,,CO,,C1CCOC1,[Na+].[OH-],test
US20100105744A1,CC(O)(c1ccc2c(c1)OCCO2)C1CC1.CSCc1cccc2cc[nH]c12>>CSCc1cccc2c(C(C)(c3ccc4c(c3)OCCO4)C3CC3)c[nH]c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100292239A1,CC(=O)CCl.Oc1c(Br)cc(Br)cc1Br>>CC(=O)COc1c(Br)cc(Br)cc1Br,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20110190255A1,CCOC(=O)c1ncn(-c2ccccn2)c1C(F)(F)F>>O=C(O)c1ncn(-c2ccccn2)c1C(F)(F)F,,CCO,O,[Na+].[OH-],,test
US09108932B2,COC(=O)c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1>>O=C(O)c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US04049829,CC(SCCCCCCCCCCSC(C)C(=O)O)C(=O)O>>CC(CO)SCCCCCCCCCCSC(C)CO,,C1CCOC1,,CCOC(C)=O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20100019229A1,CCOP(=O)(OCC)c1cscc1P(=O)(OCC)OCC>>O=P(O)(O)c1cscc1P(=O)(O)O,,CC#N,,C[Si](C)(C)I,,test
US20090149471A1,C[Si](C)(C)N=C=O.Cn1cncc1C#C[Si](C)(C)C>>C#Cc1cnc(C(N)=O)n1C,,C1CCOC1,CCOC(C)=O,O,[Li]CCCC,test
US20130123277A1,CC1(c2ccncn2)CO1.CN1CCc2c([nH]c3ccc(Cl)cc23)C1>>CN1CCc2c(n(CC(C)(O)c3ccncn3)c3ccc(Cl)cc23)C1,,CN(C)C=O,O,[H-].[Na+],,test
US05134138,COc1ccc(COC(=O)C2=C(CCl)CS[C@@H]3[C@H](NC(=O)Cc4ccccc4)C(=O)N23)cc1.Sc1ccncc1>>COc1ccc(COC(=O)C2=C(CSc3ccncc3)CS[C@@H]3[C@H](NC(=O)Cc4ccccc4)C(=O)N23)cc1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20040110786A1,O=C1COC[C@H]([C@@H](OC(=O)c2ccc([N+](=O)[O-])cc2)c2ccccc2)N1>>O=C1COC[C@H]([C@@H](O)c2ccccc2)N1,,CCO,,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20110152243A1,OC(c1ccncc1)c1c[nH]c2ccccc12>>c1ccc2c(Cc3ccncc3)c[nH]c2c1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US04990517,C=O.CNC1CNCC1CO>>CN1COCC2CNCC21,,CCCCO,,,,test
US20100130470A1,Brc1cnc2c(c1)CNCCN2.CS(=O)(=O)Cl>>CS(=O)(=O)N1CCNc2ncc(Br)cc2C1,,ClCCl,,,,test
US06093718,O=C(C1CCN(c2cc(Cl)ncn2)CC1)N1CCNCC1.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>O=C(C1CCN(c2cc(Cl)ncn2)CC1)N1CCN(S(=O)(=O)c2ccc(C(F)(F)F)cc2)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20160257633A1,CO[C@](C(=O)Cl)(c1ccccc1)C(F)(F)F.O[C@H](c1ccc(Cl)cc1I)C(F)(F)F>>CO[C@@](C(=O)O[C@H](c1ccc(Cl)cc1I)C(F)(F)F)(c1ccccc1)C(F)(F)F,CN(C)c1ccncc1,C1CCOC1,,,,test
US20080255106A1,COC(=O)c1ccc(-c2nc3cccnc3[nH]2)cc1.O=C(OO)c1cccc(Cl)c1>>COC(=O)c1ccc(-c2nc3c(Cl)ccnc3[nH]2)cc1,,CC(=O)O,,,,test
US20120178756A1,IC1CCOCC1.Sc1ccc(Br)cc1>>Brc1ccc(SC2CCOCC2)cc1,,CCOCC,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100069357A1,CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOCC4)n2)CNC3)cc1.Clc1ncccn1>>CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOCC4)n2)CN(c2ncccn2)C3)cc1,,CN(C)C=O,,,,test
US20070179156A1,CNC(=O)OC(C)(C)C.Clc1cncc(Cl)n1>>CC(C)(C)OC(=O)NCc1cncc(Cl)n1,,C1CCOC1,,[H-].[Na+],,test
US05639782,COc1cc(C2OCCO2)cc(C#N)c1OC>>COc1cc(C2OCCO2)cc(CN)c1OC,,C1CCOC1,CCOCC,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US03953430,CNc1ncccc1N.COC(=O)C1CSCC1=O>>CN1C2=C(CSC2)C(=O)Nc2cccnc21,,Cc1ccccc1,,,,test
US05047411,CN=C=S.Nc1ccc(Cc2ccccn2)cc1>>CNC(=S)Nc1ccc(Cc2ccccn2)cc1,,CCO,,,,test
US20070135456A1,C=CCn1cnc2[nH]c(=O)[nH]c(=O)c21.CCCCCI>>C=CCn1cnc2c1c(=O)[nH]c(=O)n2CCCCC,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US06514964B1,NCC(=O)OCc1ccccc1.O=Cc1ccccc1Br>>O=C(CNCc1ccccc1Br)OCc1ccccc1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20060122126A1,Brc1ccc(-c2ccccc2)c(C(Br)Br)c1.CC(=O)[O-]>>O=Cc1cc(-c2ccccc2)ccc1Br,,CC(=O)O,,Cl,,test
US20160022825A1,C(=NC1CCCCC1)=NC1CCCCC1.O=C(O)CCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>O=C(NC1CCCCC1)NC1CCCCC1,CN(C)c1ccncc1,ClCCl,,,,test
US20120302610A1,CCOC(=O)CCNC(=O)c1ccc(-c2ccc(OC)cc2C=O)cn1.Nc1ccc(Br)cc1>>CCOC(=O)CCNC(=O)c1ccc(-c2ccc(OC)cc2CNc2ccc(Br)cc2)cn1,,CCOC(C)=O,ClCCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05310743,CC(C)(C)OC(=O)N1CC[C@H](NCc2ccnc3ccccc23)C[C@H]1Cc1ccccc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CC[C@H](N(Cc2ccnc3ccccc23)C(=O)C(F)(F)F)C[C@H]1Cc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20120088748A1,CC(C)(C)OC(=O)N1CCOC(CN2C(=O)c3ccccc3C2=O)(c2ccc(Cl)c(Cl)c2)CC1>>CC(C)(C)OC(=O)N1CCOC(CN)(c2ccc(Cl)c(Cl)c2)CC1,,CCO,,NN,,test
US03992535,COC(=O)C1=C(O)c2ccc3ccccc3c2S(=O)(=O)N1C.Nc1ccccc1>>CN1C(C(=O)Nc2ccccc2)=C(O)c2ccc3ccccc3c2S1(=O)=O,,ClCCCl,,,,test
US20050020684A1,OCc1ccc(OCc2ccccc2)cc1Cl>>O=Cc1ccc(OCc2ccccc2)cc1Cl,O=[Mn]=O,ClCCl,,,,test
US20120190649A1,CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3cc(C=O)ccc3c2)CC1.CCOC(=O)CC(C)N>>CCOC(=O)CC(C)NCc1ccc2cc(O[C@@H]3CC[C@@H](C(C)(C)C)CC3)ccc2c1,,CC(Cl)Cl,,CC(=O)O,O=C([O-])O.[Na+],test
US20090203700A1,OC/C(=C/c1cccnc1Cl)c1ccc(F)cc1>>O=C/C(=C/c1cccnc1Cl)c1ccc(F)cc1,,CCOC(C)=O,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05322848,CI.OC1CCN(Cc2ccccc2)C1>>COC1CCN(Cc2ccccc2)C1,,C1CCOC1,,[H-].[Na+],,test
US20130053382A1,CCCC[Sn](CCCC)(CCCC)c1cc(C)nn1C1CCCCO1.COC(=O)c1csc(Br)n1>>COC(=O)c1csc(-c2cc(C)nn2C2CCCCO2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,,,test
US20090270402A1,CC(C)C(=O)Cl.NNc1ccc(Cl)nn1>>CC(C)c1nnc2ccc(Cl)nn12,,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20030100555A1,C1CCOC1.Cc1cc(C)c(/C=C2\C(=O)N(C(=O)n3ccnc3)c3ccccc32)[nH]1.O=C(O)C=Cc1ccccc1>>Cc1cc(C)c(/C=C2\C(=O)N(C(=O)Oc3ccc(/C=C/C(=O)O)cc3)c3ccccc32)[nH]1,CCN(CC)CC,,,,,test
US20070148164A1,Cc1cc(Oc2nc(C3CC3C(=O)OC(C)(C)C)c(F)cc2F)cc(-c2cccc(CN)c2)c1.O=C(O)C(F)(F)F>>Cc1cc(Oc2cccc([C@@H]3C[C@H]3C(=O)O)n2)cc(-c2cccc(CN)c2)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20050256099A1,Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCN(C)CC3)CC2)cc([N+](=O)[O-])c1N>>Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCN(C)CC3)CC2)cc(N)c1N,[Pd],C1CCOC1,,[H][H],,test
US20120149662A1,CC(C)(C)C(=O)OCn1ccc2c(-c3cnn(C(CC#N)C4CCCCC4)c3)cnnc21>>N#CCC(C1CCCCC1)n1cc(-c2cnnc3[nH]ccc23)cn1,,CO,,[Na+].[OH-],,test
US20060217382A1,COc1cc(Nc2ncc(C(C)NC(=O)c3cccc4cccnc34)nn2)cc(OC)c1OC>>COc1cc(Nc2ncc3c(C)nc(-c4cccc5cccnc45)n3n2)cc(OC)c1OC,,ClCCCl,,O=P(Cl)(Cl)Cl,,test
US20090124616A1,CC1(C)OB(/C=C/CCCCl)OC1(C)C.CCOC(=O)c1c(Br)c2cc(F)ccc2n1CCCOc1cccc2ccccc12>>CCOC(=O)c1c(/C=C/CCCCl)c2cc(F)ccc2n1CCCOc1cccc2ccccc12,CC(=O)O[Pd]OC(C)=O,,,COc1cccc(OC)c1-c1ccccc1P(C1CCCCC1)C1CCCCC1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20050227959A1,NCCc1ccc(F)cc1.O=S(=O)(Cl)c1ccc(Br)s1>>O=S(=O)(NCCc1ccc(F)cc1)c1ccc(Br)s1,,C1CCOC1,,CCN(CC)CC,,test
US20150080364A1,C[C@H]1CN(Cc2ccc(N3CCOCC3)cc2OC(F)(F)F)CCN1.O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O>>C[C@H]1CN(Cc2ccc(N3CCOCC3)cc2OC(F)(F)F)CCN1C(=O)ON1C(=O)CCC1=O,,CC#N,,CCN(CC)CC,,test
US20040198786A1,Cc1oc(-c2ccc(F)cc2)nc1COC1CCCC(O)C1.O=C(Cl)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>Cc1oc(-c2ccc(F)cc2)nc1CO[C@@H]1CCC[C@H](OC(=O)c2cc([N+](=O)[O-])cc([N+](=O)[O-])c2)C1,,c1ccncc1,,,,test
US05616590,CCN(CC)C(=O)Cl.CCN(CC)C(=S)Oc1cccnc1F>>CCN(CC)C(=O)C1(OC(=S)N(CC)CC)C=CC=NC1F,,C1CCOC1,O,Cl,[Li]CCCC,test
US20050038104A1,CC(C)(C)OC(=O)NCCc1cc(F)c(C(=O)O)c(F)c1.N>>CC(C)(C)OC(=O)NCCc1cc(F)c(C(N)=O)c(F)c1,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US20130267510A1,CCC(=O)OC(=O)CC.COc1cccc(O)c1C=O>>COc1cccc2oc(=O)c(C)cc12,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150166587A1,O=C1OCCO1.O=S(=O)([N-]S(=O)(=O)C(F)(F)F)C(F)(F)F.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>O=S(=O)([N-]S(=O)(=O)C(F)(F)F)C(F)(F)F.OCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1,,CO,,N#N,,test
US20070225280A1,CCOC(=O)c1cnn(C2CCC2)c1Cl>>O=C(O)c1cnn(C2CCC2)c1Cl,,CO,O,[Li+].[OH-],,test
US20150225375A1,CC1(CN(C(=O)C(F)(F)F)[C@@H]2C[C@H]2c2ccccc2)CCN(C(=O)OC(C)(C)C)CC1>>CC1(CN(C(=O)C(F)(F)F)[C@@H]2C[C@H]2c2ccccc2)CCNCC1,,ClCCl,,Cl,,test
US20140057902A1,CC(C)I.COCc1cn(C2=NCC(=O)N3CCc4c(O)cccc4C3=C2)cn1>>COCc1cn(C2=NCC(=O)N3CCc4c(OC(C)C)cccc4C3=C2)cn1,,C1CCOC1,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05100874,C(=NC1CCCCC1)=NC1CCCCC1.C[C@H](NC(=O)OC(C)(C)C)C(=O)O.ClCCl.On1nnc2ccccc21>>C[C@H](NC(=O)OC(C)(C)C)C(=O)NOCc1ccccc1,,CN(C)C=O,ClCCl,CS(C)=O,,test
US05424440,C1CCOC1.COP(=O)(Cl)OC.NC(=O)c1nc2ccc(O)cc2s1>>COP(=O)(O)OC.NC(=O)c1nc2ccc(O)cc2s1,,C1CCOC1,,CCN(CC)CC,,test
US20160221959A1,CC(=O)OCC(=O)Cl.Nc1ccc(I)cc1>>CC(=O)OCC(=O)Nc1ccc(I)cc1,,ClCCl,,O,,test
US05834454,CCOC(=O)c1cc2c(C)cccc2[nH]1.Cc1ccc(S(=O)(=O)OCCNC(=O)OC(C)(C)C)cc1>>CCOC(=O)c1cc2c(C)cccc2n1CCNC(=O)OC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US08080565B2,C1CC2(CCN1)OCCO2.COc1cccc(OC)c1C=O>>COc1cccc(OC)c1CN1CCC2(CC1)OCCO2,[Pd],CO,,[H][H],,test
US20130096136A1,O=C(Oc1ccc(O)c(NC(=S)Nc2ccc(Cl)cc2)c1)c1ccccc1>>O=C(Oc1ccc2oc(Nc3ccc(Cl)cc3)nc2c1)c1ccccc1,,CCOC(C)=O,O,ClCCCl,,test
US05789394,Cc1ccc(S(=O)(=O)Cl)cc1.O=C1CCC(CO)O1>>Cc1ccc(S(=O)(=O)OCC2CCC(=O)O2)cc1,,ClCCl,,c1ccncc1,,test
US20160237067A1,Cc1ccc(C(=O)N2CCOCC2)cc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1.Cl>>Cc1ccc(C(=O)N2CCOCC2)cc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1.Cl,,C1COCCO1,,,,test
US20150087618A1,Cc1c(Br)ccc([N+](=O)[O-])c1NC(=O)C(F)(F)F>>Cc1c(Br)ccc([N+](=O)[O-])c1N,,CO,Cl,O,O=C([O-])[O-].[K+].[K+],test
US20160052922A1,CC(C)NN.CCO/C=C(/C#N)C(=O)OCC>>CCOC(=O)c1cnn(C(C)C)c1N,,CCO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20080242643A1,CC(C)(C)[Si](C)(C)OC/C(=C(\CO)c1ccc(S(C)(=O)=O)cc1)c1ccccc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.O=[N+]([O-])OCC(CO)O[N+](=O)[O-]>>CC(C)(C)[Si](C)(C)OC/C(=C(\COC(=O)OCC(CO[N+](=O)[O-])O[N+](=O)[O-])c1ccc(S(C)(=O)=O)cc1)c1ccccc1,,ClCCl,,c1ccncc1,,test
US05554620,Brc1c(COC2CCCCO2)cccc1COC1CCCCO1.O=Cc1ccccn1>>OC(c1ccccn1)c1c(COC2CCCCO2)cccc1COC1CCCCO1,,CCOCC,,CN(C)CCN(C)C,[Li]CCCC,test
US20090192322A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)O[C@@H]2CN[C@@H]3[C@@H](O)CO[C@H]23)cc1>>Cc1ccc(S(=O)(=O)O[C@@H]2CN(C(=O)OC(C)(C)C)[C@@H]3[C@@H](O)CO[C@H]23)cc1,,CCOC(C)=O,,,,test
US20050227953A1,CC1C2CCC3C4CC=C5CC(O)CCC5(C)C4CCC32CN1C.CI>>COC1CCC2(C)C(=CCC3C2CCC24CN(C)C(C)C2CCC34)C1,,CN(C)C=O,,[H-].[Na+],,test
US20110039843A1,Nc1cc(C(F)(C(F)(F)F)C(F)(F)F)ccc1O.O=C(O)c1ccncc1Cl>>O=C(Nc1cc(C(F)(C(F)(F)F)C(F)(F)F)ccc1O)c1ccncc1Cl,,c1ccncc1,,CCN=C=NCCCN(C)C,,test
US20120208812A1,Cn1ncnc1-c1ccccc1C(=O)N1CC2CN(C(=O)OC(C)(C)C)CC2C1>>Cn1ncnc1-c1ccccc1C(=O)N1CC2CNCC2C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US03992535,COC(=O)C1=C(O)c2ccc3ccccc3c2S(=O)(=O)N1.Nc1nccs1>>O=C(Nc1nccs1)C1=C(O)c2ccc3ccccc3c2S(=O)(=O)N1,,Cc1ccccc1C,,,,test
US20100298336A1,CCN1CCN(c2ccc(CBr)c(Cl)c2)CC1.Cc1cc(O)nc(S)n1>>CCN1CCN(c2ccc(CSc3nc(C)cc(O)n3)c(Cl)c2)CC1,,CCO,,CCN(CC)CC,,test
US20090176786A1,CN(C(=O)Cl)c1ccc(SC(F)(F)F)cc1F.NCc1ccccc1>>CN(C(=O)NCc1ccccc1)c1ccc(SC(F)(F)F)cc1F,,COC(C)(C)C,,CCN(CC)CC,,test
US20020132319A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C(OC1CCCCC1)C(c1ccccc1)n1cnc2[nH]ncc2c1=O>>O=C(OC1CCCCC1)C(c1ccccc1)n1cnc2[nH]ncc2c1=S,,Cc1ccccc1C,,,,test
US20090197864A1,CC(=O)c1cccc(OC(F)(F)F)c1>>CC(O)c1cccc(OC(F)(F)F)c1,O,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150291624A1,CC(C)(C)OC(=O)c1cn(S(C)(=O)=O)c2ccc(F)cc12>>CS(=O)(=O)n1cc(C(=O)O)c2cc(F)ccc21,,CCOC(C)=O,,Cl,,test
US06001855,CCOC(=O)C(=O)CBr.NC(=S)N=C(N)N>>Br.CCOC(=O)c1csc(NC(=N)N)n1,,CCO,,,,test
US20130143907A1,Br.Cc1cc(C)c(N)c(Cl)n1>>Cc1cc(C)c(Br)c(Cl)n1,[Cu]Br,O,,O=N[O-].[Na+],,test
US20120046285A1,CNC(=O)C1CCCN(CC(=O)O)C1.COc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CN)c3Cl)cccc2n1Cc1ccccn1>>CNC(=O)C1CCCN(CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c3nc(OC)n4Cc3ccccn3)c2Cl)C1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US07045545B1,CC(N)Cc1ccc2occc2c1.CCOC(C)=O>>CC(=O)Cc1ccc2occc2c1,,CCOCC,,Cl,,test
US05698577,O=C1N[C@@H]2CCN[C@H]12.O=C=Nc1ccccc1>>O=C1N[C@@H]2CCN(C(=O)Nc3ccccc3)[C@H]12,CCN(CC)CC,ClC(Cl)Cl,,,,test
US20040009995A1,CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cnc(Cl)c(Br)c1.NCc1ccccn1.O=C(O)C(F)(F)F>>CSc1sc(C(=N)N)cc1S(=O)(=O)c1cnc(NCc2ccccn2)c(Br)c1.O=C(O)C(F)(F)F,,C1CCOC1,,ClC(Cl)Cl,,test
US20150191503A1,CC(=O)Oc1cc(C)cc(C)c1C(C)(C)CC(=O)O.O=C1CCC(=O)N1O>>CC(=O)Oc1cc(C)cc(C)c1C(C)(C)CC(=O)ON1C(=O)CCC1=O,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04834907,CCCCCCCCOc1ccc(-c2ccc(C(C)=O)cc2)cc1.OO>>CCCCCCCCOc1ccc(-c2ccc(O)cc2)cc1,,Cc1ccccc1,,O=CO,,test
US20050113414A1,CCc1cccc(N=C=O)c1.NC1CCN(CC23CC4CC(CC(C4)C2)C3)CC1>>CCc1cccc(NC(=O)NC2CCN(CC34CC5CC(CC(C5)C3)C4)CC2)c1,,ClCCl,,,,test
US06350759B1,CCOC(C)=O.Cc1ccccc1.O=[N+]([O-])c1ccc(O)cc1>>CC(C)(C)Oc1ccc([N+](=O)[O-])cc1,,CCOC(C)=O,,,,test
US05831072,O=C(OC[C@H]1O[C@@H](n2cnc3c2N=CNCC3=O)[C@@H](F)[C@@H]1OC(=O)c1ccccc1)c1ccccc1>>O=C1CNC=Nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F,,CO,,C[O-].[Na+],,test
US20040116698A1,CC(C)[C@H](N)CO.Cn1c(=O)c(Oc2ccccc2F)cc2cnc(S(C)(=O)=O)nc21>>CC(C)[C@@H](CO)Nc1ncc2cc(Oc3ccccc3F)c(=O)n(C)c2n1,,CN1CCCC1=O,,CO,O,test
US20130190332A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4ccc(Br)cn4c3-c3ccccc3)cc2)CCC1.Cc1cc(B(O)O)n(C(=O)OC(C)(C)C)n1>>Cc1cc(-c2ccc3nc(-c4ccc(C5(NC(=O)OC(C)(C)C)CCC5)cc4)c(-c4ccccc4)n3c2)n(C(=O)OC(C)(C)C)n1,,C1COCCO1,O,,,test
US05420322,C[Si](C)(C)N[Si](C)(C)C.[Li]>>C[Si](C)(C)N[Si](C)(C)C.[Li],,CCCCCC,,[H][H],,test
US05919777,COC(=O)[C@@H](Cc1ccccc1)NCCN>>O=C1NCCN[C@@H]1Cc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20040009976A1,BrCc1ccccc1.Cc1cc2cc(Cl)ccc2[nH]1>>Cc1cc2cc(Cl)ccc2n1Cc1ccccc1,C1COCCOCCOCCOCCOCCO1,,,[K+].[OH-],,test
US20060173008A1,CCn1nc(-c2ccccc2)c(C(C)=O)c([N+](=O)[O-])c1=O.Nc1ccc(O)c2ncccc12>>CCn1nc(-c2ccccc2)c(C(C)=O)c(Nc2ccc(O)c3ncccc23)c1=O,,CCO,,,,test
US20140213571A1,CCOC(=O)C1Oc2ccc(Cl)nc2-c2cc3c(F)cccc3n21>>OCC1Oc2ccc(Cl)nc2-c2cc3c(F)cccc3n21,,CO,ClCCl,O,[BH4-].[Na+],test
US20150119362A1,COC(=O)C1SCCCC1=O.N=C(N)C1CCCC1>>Oc1nc(C2CCCC2)nc2c1SCCC2,,CCO,,C[O-].[Na+],,test
US20150057265A1,CC(C)(C)OC(=O)N[C@H]1CCCN(c2ccncc2N)C1.CCc1cnc2c(C(=O)O)c(NC(=O)OC(C)(C)C)oc2c1>>CCc1cnc2c(C(=O)Nc3cnccc3N3CCC[C@H](NC(=O)OC(C)(C)C)C3)c(NC(=O)OC(C)(C)C)oc2c1,,ClCCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100144731A1,COC(=O)C1(c2ccc(Nc3nc(Cl)nc4c3CCC4)cc2)CCC1.Oc1ccccc1>>COC(=O)C1(c2ccc(Nc3nc(Oc4ccccc4)nc4c3CCC4)cc2)CCC1,[Cu],CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05962479,CI.Cc1cc(C)c(Nc2nc(C)nc(Cl)c2C)c(C)c1>>Cc1cc(C)c(N(C)c2nc(C)nc(Cl)c2C)c(C)c1,,C1CCOC1,,[H-].[Na+],,test
US20090023729A1,CCOC(C)=O.CN(C)C=O.Cl.NCC1CC1.O=[N+]([O-])c1cccnc1Cl>>ClCc1nc2cccnc2n1CC1CC1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20080009482A1,CC(C)(C)OC(=O)NC1CCC(N2CCCC2)CC1>>NC1CCC(N2CCCC2)CC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20070238730A1,CC(=O)NN.CC(C)(C)OC(=O)NCCC(=O)O.CCN(C(C)C)C(C)C>>CCC(=O)NNC(=O)CCNC(=O)OC(C)(C)C,,C1CCOC1,ClCCl,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,test
US20120136008A1,Cc1ccc(S(=O)(=O)OCCc2ccc(C)nc2)cc1.Cc1ccc2[nH]c3c(c2c1)CN(CC(F)(F)F)CC3>>Cc1ccc2c(c1)c1c(n2CCc2ccc(C)nc2)CCN(CC(F)(F)F)C1,,CN(C)C=O,,[H-].[Na+],,test
US20100234395A1,CNO.COc1ccc(-c2cc(C3CC4CCC(C3)N4)nn2-c2ccc(OC)cc2)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc(-c2cc(C3CC4CCC(C3)N4C(=O)N(C)O)nn2-c2ccc(OC)cc2)cc1,,C1CCOC1,O,CCN(CC)CC,Cl,test
US20080280917A1,CC(C)(C)OC(=O)Nc1ccc(=O)n(C(C)(C)CO)c1.COc1ccc2c(I)ccnc2c1>>COc1ccc2c(OCC(C)(C)n3cc(NC(=O)OC(C)(C)C)ccc3=O)ccnc2c1,[Cu]I,CN(C)C=O,,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US20140371283A1,Cc1cc(C=O)ccc1OC(F)F.Fc1cc(F)cc(C2SCCCS2)c1>>Cc1cc(C(O)C2(c3cc(F)cc(F)c3)SCCCS2)ccc1OC(F)F,,C1CCOC1,,[Li]CCCC,,test
US20030229120A1,BrBr.O=C(O)c1cc2ccccc2cc1O>>O=C(O)c1cc2ccccc2c(Br)c1O,,CC(=O)O,,,,test
US20110059943A1,CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(Nc3nc(C(=O)OC)c(C)s3)nc21>>CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(Nc3nc(C(=O)O)c(C)s3)nc21,,CCO,,Cl,[Na+].[OH-],test
US20090203700A1,Cc1cccnc1Cl.O=C1CCC(=O)N1Br>>Clc1ncccc1CBr,O=C(OOC(=O)c1ccccc1)c1ccccc1,c1ccccc1,,,,test
US20080171728A1,CCCCCCCC(C)O>>CCCCCCCC(C)=O,,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20120245366A1,CC1(C)C2CCC1(C(=O)O)C(=O)C2.CI>>COC(=O)[C@@]12CC[C@@H](CC1=O)C2(C)C,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20080287396A1,COc1c(N2C[C@@H]3[C@@H](CCCN3CC(P(=O)(OC)OC)P(=O)(OC)OC)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12>>COc1c(N2C[C@@H]3[C@@H](CCCN3CC(P(=O)(O)O)P(=O)(O)O)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12,,ClCCl,,C[Si](C)(C)Br,,test
US05220018,CC(=O)NC(=O)c1cccc([N+](=O)[O-])c1>>CC(=O)NC(=O)c1cccc(N)c1,[Pd],CCO,,,,test
US20080153812A1,COCCN1CCC(c2ccc(C(=O)OC)cc2)CC1.COc1cc(CCc2cc(N)[nH]n2)cc(OC)c1>>COCCN1CCC(c2ccc(C(=O)Nc3cc(CCc4cc(OC)cc(OC)c4)n[nH]3)cc2)CC1,,Cc1ccccc1,,C[Al](C)C,,test
US06002008,C=CC(=O)Cl.N#Cc1cnc2ccc(N)cc2c1Nc1cccc(F)c1>>C=CC(=O)Nc1ccc2ncc(C#N)c(Nc3cccc(F)c3)c2c1,,C1CCOC1,,CCN(CC)CC,,test
US20030176454A1,O=P(Cl)(Cl)Cl.Oc1ncnc2c1CCc1sccc1-2>>Clc1ncnc2c1CCc1sccc1-2,,CCOC(C)=O,,Cc1ccccc1,,test
US20150175562A1,CC(C)(C)c1cc(-c2nc(C(=O)NC3COC3)ncc2C=C2CCCCC2)cc(C(C)(C)C)c1>>CC(C)(C)c1cc(-c2nc(C(=O)NC3COC3)ncc2CC2CCCCC2)cc(C(C)(C)C)c1,[Pd],CO,ClC(Cl)Cl,[Na+].[OH-],,test
US20040259924A1,CC(C)(C)[Si](C)(C)OC1CC(CNCc2ccccc2)Oc2ccccc21.O=C1c2ccccc2S(=O)(=O)N1CCCCBr>>CC(C)(C)[Si](C)(C)OC1CC(CN(CCCCN2C(=O)c3ccccc3S2(=O)=O)Cc2ccccc2)Oc2ccccc21,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,O,test
US05171753,CC(N)(CO)CO.c1ccc([C@H]2O[C@@H]2c2ccccc2)cc1>>CC(CO)(CO)NC(c1ccccc1)C(O)c1ccccc1,,CO,O,,,test
US04826866,CCOC(=O)C(Cl)C(C)=O.CSc1cccc(NC(=S)NN)c1>>CCOC(=O)c1c(Nc2cccc(SC)c2)n[nH]c1C,,CCO,,Cl,,test
US20150065477A1,CC(C)(C)OC(=O)N1Cc2cn(-c3ncccc3C(=O)NC(Cc3ccccc3)C(O)C(N)=O)nc2C1>>CC(C)(C)OC(=O)N1Cc2cn(-c3ncccc3C(=O)NC(Cc3ccccc3)C(=O)C(N)=O)nc2C1,,CC#N,O,,,test
US20090215767A1,COc1ccc2c(=O)c(-c3ccc(O)cc3)coc2c1.ClCC1CO1>>COc1ccc2c(=O)c(-c3ccc(OCC4CO4)cc3)coc2c1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20050070592A1,COc1ccc(-c2ccc3c(c2)c(C)c(C)n3Cc2ccccc2)cc1>>Cc1c(C)n(Cc2ccccc2)c2ccc(-c3ccc(O)cc3)cc12,,ClCCl,,BrB(Br)Br,,test
US20150045399A1,COC(=O)c1cc(C(=O)NNC(=O)c2cccc(S(C)(=O)=O)c2)n(-c2ccccc2Cl)n1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COC(=O)c1cc(-c2nnc(-c3cccc(S(C)(=O)=O)c3)s2)n(-c2ccccc2Cl)n1,,Cc1ccccc1,,c1ccncc1,,test
US06258948B1,CC(=O)N1C[C@H](NC(=O)c2ccccc2)C(=O)N(CC(=O)OCc2ccccc2)c2ccccc21>>CC(=O)N1CC(NC(=O)c2ccccc2)C(=O)N(CC(=O)O)c2ccccc21,[Pd],CO,,,,test
US20080153836A1,COC(=O)c1cc(-c2ccnn2C(C)C)c(C(F)(F)F)cc1N.CS(=O)(=O)NN.ClCCl.[OH-]>>CC(C)n1nccc1-c1cc2c(=O)n(NS(C)(=O)=O)c(=O)[nH]c2cc1C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20150344423A1,CCOC(=O)c1cn(Cc2ccc(OC)cc2)c(CC2CCCCC2)c1C>>CCOC(=O)c1c[nH]c(CC2CCCCC2)c1C,,CC#N,,,,test
US20160102071A1,CCOCCOc1ccc(-c2csc3ccc(COc4ccc(C5(CC(=O)OCC)CC(=O)C5)cc4)cc23)c(C)c1>>CCOCCOc1ccc(-c2csc3ccc(COc4ccc(C5(CC(=O)O)CC(=O)C5)cc4)cc23)c(C)c1,,CC#N,O,Cl,[Na+].[OH-],test
US20110076291A1,CC(C)n1ncnc1-c1nc2c(s1)CCOc1cc(C3CCNCC3)ccc1-2.COCCBr>>COCCN1CCC(c2ccc3c(c2)OCCc2sc(-c4ncnn4C(C)C)nc2-3)CC1,,CN(C)C=O,ClCCl,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US06953850B1,COc1ccc(CO[C@H]2[C@H](O)[C@@H](CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)O[C@@H](SC)[C@@H]2N=[N+]=[N-])cc1.O=C(Cl)c1ccccc1-c1ccccc1>>COc1ccc(CO[C@H]2[C@H](OC(=O)c3ccccc3-c3ccccc3)[C@@H](CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)O[C@@H](SC)[C@@H]2N=[N+]=[N-])cc1,CN(C)c1ccncc1,ClCCCl,,,,test
US20050148656A1,CCCCCCCCC(=O)O.NCc1ccc(F)cc1F>>CCCCCCCCC(=O)NCc1ccc(F)cc1F,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US04562199,CCOC(=O)C=Cc1ccc(Cn2ccnc2)c(Br)c1.NCCN>>CCOC(=O)C=Cc1ccc(Cn2ccnc2)c(C#N)c1,,CN(C)C=O,,O,,test
US04189171,CCn1c(C)cc2ccccc21.O=C1OC(=O)c2ccccc21>>CCn1c(C)c(C(=O)c2ccccc2C(=O)O)c2ccccc21,,ClCCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20130217666A1,O=C(O)c1nc2c(s1)CCOc1cc(F)c(Br)cc1-2.[NH4+]>>NC(=O)c1nc2c(s1)CCOc1cc(F)c(Br)cc1-2,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04421758,Cc1ccc(S(=O)(=O)OC[C@H]2CCC[C@@H](OCc3ccc(Cl)cc3Cl)O2)cc1.c1c[nH]cn1>>Clc1ccc(CO[C@@H]2CCC[C@H](Cn3ccnc3)O2)c(Cl)c1,,CN(C)C=O,,[H-].[Na+],,test
US20160009701A1,C[C@H]1CNC[C@@H](C)O1.O=C(O)c1cc(Br)cc(C(F)(F)F)c1>>C[C@H]1CN(C(=O)c2cc(Br)cc(C(F)(F)F)c2)C[C@@H](C)O1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20090029965A1,CS(=O)(=O)Cl.Cc1ccc2c(c1)Nc1c(cnn1C)CN2C(=O)c1ccc(CCC(=O)N2CCNCC2)c(C)c1>>Cc1ccc2c(c1)Nc1c(cnn1C)CN2C(=O)c1ccc(CCC(=O)N2CCN(S(C)(=O)=O)CC2)c(C)c1,,CCN(CC)CC,ClCCl,,,test
US04873236,CCCN(CCC)CC1CCCN(CC#N)C1>>N#CCN1CCC(CN2CCCCC2)C1,,CO,ClCCl,N,,test
US20100120739A1,O=C(Cl)C(=O)Cl.O=C(O)Cc1c(F)cc2ncccc2c1F>>O=C(Cl)Cc1c(F)cc2ncccc2c1F,,ClCCl,,CN(C)C=O,,test
US03984412,CCCCNc1c(N)c(N)nc(C)c1C(=O)OCC.Cc1ccccc1>>CCCCNc1c(C(=O)OCC)c(C)nc2nc(C)c(C)nc12,,O,,,,test
US20130150407A1,COC(=O)Cc1cc2ccc(F)cc2c(C2CCNCC2)c1C.O=S(=O)(Cl)N1CCCC1>>COC(=O)Cc1cc2ccc(F)cc2c(C2CCN(S(=O)(=O)N3CCCC3)CC2)c1C,,ClCCl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US05811432,O=C1Nc2cc(Cl)cnc2C1C(=O)c1cc(Cl)cs1.O=C=NS(=O)(=O)Cl>>NC(=O)N1C(=O)C(C(=O)c2cc(Cl)cs2)c2ncc(Cl)cc21,,CC#N,,,,test
US20150239824A1,BrCCCBr.CCN(CC)CC>>CC[N+](CC)(CC)CCCBr.[Br-],,Cc1ccccc1,,,,test
US20120142668A1,CC[C@@H](/C=C/C(=O)O)NC(=O)[C@@H]1C[C@H](F)CN1C(=O)OC(C)(C)C.Nc1nnc(C(F)(F)F)s1>>CC[C@@H](/C=C/C(=O)Nc1nnc(C(F)(F)F)s1)NC(=O)[C@@H]1C[C@H](F)CN1C(=O)OC(C)(C)C,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05565571,Nc1cc(F)c(-c2cccnc2)c(F)c1.O=C(Cl)OCc1ccccc1>>O=C(Nc1cc(F)c(-c2cccnc2)c(F)c1)OCc1ccccc1,,ClCCl,,C1CCOC1,O=C([O-])O.[Na+],test
US20050043354A1,CC(=O)N1CCC(=NO)CC1>>CC(=O)N1CCC(N)CC1,[Ni],CCO,,,,test
US04663453,CN1CCN(C(=O)Nc2ccccc2N2CCc3cc(Cl)ccc32)CC1>>CN1CCN(C2=Nc3ccccc3N3CCc4cc(Cl)cc2c43)CC1,,ClCCl,,ClCCCl,,test
US20140249143A1,CCOC(=O)c1cc2c(N)cccc2[nH]1.O=C(CC(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1cc2c(ccc3c(C(F)(F)F)cc(C(F)(F)F)nc32)[nH]1,,CC(=O)O,CCOC(C)=O,,,test
US20150191483A1,C=C(c1ccc(C(F)(C(F)(F)F)C(F)(F)F)cc1)S(=O)(=O)c1cccc(Br)c1.COCN(Cc1ccccc1)C[Si](C)(C)C>>O=S(=O)(c1cccc(Br)c1)C1(c2ccc(C(F)(C(F)(F)F)C(F)(F)F)cc2)CCN(Cc2ccccc2)C1,O=C(O)C(F)(F)F,ClCCl,,,,test
US20120101110A1,Cc1cc(C)nc(Cl)n1.O=C1N(Cc2ccccc2-n2nccn2)CCCC12CCNCC2>>Cc1cc(C)nc(N2CCC3(CCCN(Cc4ccccc4-n4nccn4)C3=O)CC2)n1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20080167378A1,CC(C)(C)OC(=O)CBr.CCOC(=O)CCc1ccc(OCc2cccc(O)c2)c(F)c1>>CCOC(=O)CCc1ccc(OCc2cccc(OCC(=O)OC(C)(C)C)c2)c(F)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20060025474A1,CCC(CC)(c1ccc(O)c(C)c1)c1ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1.O=C1CCC[C@@H](CO)O1>>CCC(CC)(c1ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1ccc(OC[C@@H]2CCCC(=O)O2)c(C)c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06329389B1,BrBr.OCCc1ccc(-c2ccccc2)cc1>>BrCCc1ccc(-c2ccccc2)cc1,,CC#N,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090054462A1,CCOC(=O)[C@H]1CC[C@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@@H](c2ccc(F)cc2)[C@@H]1C(=O)OCC>>CCOC(=O)[C@@H]1[C@@H](C(=O)O)CC[C@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H]1c1ccc(F)cc1,,CO,,[Na+].[OH-],,test
US04837333,C=CCBr.COc1ccc(CC[Mg]I)cc1>>C=CCCCc1ccc(OC)cc1,,C1CCOC1,,,,test
US05650533,CNC.O=[N+]([O-])c1cc(C(F)(F)F)ccc1C(Br)c1cnoc1C1CC1>>CN(C)C(c1ccc(C(F)(F)F)cc1[N+](=O)[O-])c1cnoc1C1CC1,,CCO,ClCCl,,,test
US20130053572A1,CCCCC/C=C\C/C=C\CCCCCCCCO.CCOC1(OCC)CCN(C(=O)OCC2c3ccccc3-c3ccccc32)CC1.Cc1ccc(S(=O)(=O)[O-])cc1.Cc1ccccc1.c1cc[nH+]cc1>>CCCCC/C=C\C/C=C\CCCCCCCCOC1(OCCCCCCCC/C=C\C/C=C\CCCCC)CCN(C(=O)OCC2c3ccccc3-c3ccccc32)CC1,,ClCCl,,,,test
US20100076026A1,CCOC(=O)Cc1ccc(N=C=O)c(Cl)c1.Clc1ccc(-n2nc3ccccc3c2NC2CCCCC2)cc1>>CCOC(=O)Cc1ccc(NC(=O)N(c2c3ccccc3nn2-c2ccc(Cl)cc2)C2CCCCC2)c(Cl)c1,,ClCCCl,,CCN(CC)CC,,test
US20060211734A1,CN1CCC(Oc2cccc(N)c2F)CC1.O=C(Cl)c1ccccc1Cl>>CN1CCC(Oc2cccc(NC(=O)c3ccccc3Cl)c2F)CC1,,C1COCCO1,,,,test
US20090270350A1,CSc1ccccc1Cn1c(C)cc(OCc2ccccc2CN2C(=O)c3ccccc3C2=O)c(Cl)c1=O>>CSc1ccccc1Cn1c(C)cc(OCc2ccccc2CN)c(Cl)c1=O,,CO,,NN,O,test
US06855698B2,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.O=C1NC(=O)c2c1c1c3cc(F)c(F)cc3[nH]c1c1c2c2cc(F)c(F)cc2n1[C@@H]1O[C@H](CO)C[C@H](O)[C@H]1OCc1ccccc1>>CC(C)(C)[Si](OC[C@@H]1C[C@H](O)[C@@H](OCc2ccccc2)[C@H](n2c3cc(F)c(F)cc3c3c4c(c5c6cc(F)c(F)cc6[nH]c5c32)C(=O)NC4=O)O1)(c1ccccc1)c1ccccc1,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US20110071199A1,BrP(Br)Br.OCc1cc(F)c(Cl)cc1F>>Fc1cc(CBr)c(F)cc1Cl,,CCOCC,ClCCl,O,,test
US20120142717A1,C=Cc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)c(F)c1.OO>>OCCc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)c(F)c1,,C1CCOC1,,B1C2CCCC1CCC2,[Na+].[OH-],test
US03959296,CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccc(O)c(OC)c1.CN(C)CCCCl>>CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccc(OCCCN(C)C)c(OC)c1,,CCO,,[Na],,test
US20150342185A1,COc1cccc(Cl)c1C=O.O=C1CC2CCC1C2>>COc1cccc(Cl)c1/C=C1/C(=O)C2CCC1C2,,CCO,,[K+].[OH-],,test
US04889858,CCOC(=O)c1cc(F)ccc1COc1cccc(F)c1>>O=C(O)c1cc(F)ccc1COc1cccc(F)c1,,CCO,,[Na+].[OH-],,test
US05108486,CCN(CC)c1c(Cl)cc(N)cc1Cl.S=C(Cl)Cl>>CCN(CC)c1c(Cl)cc(N=C=S)cc1Cl,,ClC(Cl)Cl,O,O=C([O-])[O-].[K+].[K+],,test
US20100130558A1,CC(C)(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)O.CI>>CN(C(=O)OC(C)(C)C)[C@@H](CC(C)(C)C)C(=O)O,,C1CCOC1,,CCOC(C)=O,[H-].[Na+],test
US05677302,CCCCn1sc2nccn2c1=O.N#CBr>>Brc1nsc2nccn12,,ClCCl,,,,test
US20110136778A1,C=CCBr.CC(C)(C)OC(=O)N1CCCC(C(=O)O)C1>>C=CCOC(=O)C1CCCN(C(=O)OC(C)(C)C)C1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080207654A1,BrCC1CC1.CCCCc1nc(C)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1>>CCCCc1nc(C)n(CC2CC2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1,,CN(C)C=O,O,CCOC(C)=O,[H-].[Na+],test
US20130096118A1,C=O.CCOC(=O)C(N)Cc1c[nH]c2c(C(N)=O)ccc(Br)c12>>CCOC(=O)C1Cc2c([nH]c3c(C(N)=O)ccc(Br)c23)CN1,,CO,Cl,,,test
US20150376130A1,CCOC(=O)c1cc(F)cnc1Cl.Nc1ccc(F)cc1>>CCOC(=O)c1cc(F)cnc1Nc1ccc(F)cc1,,ClCCl,,,,test
US20110212918A1,COc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(CCO)c1>>O=S(=O)(Nc1ccc2c(c1)B(O)OC2)c1ccc(O)cc1CCO,,ClCCl,,BrB(Br)Br,,test
US20160115126A1,Cc1[nH]c2c(C(N)=O)cc(F)c(N3C[C@H]4[C@H](CCCN4C(=O)OC(C)(C)C)C3)c2c1C>>Cc1[nH]c2c(C(N)=O)cc(F)c(N3C[C@@H]4NCCC[C@@H]4C3)c2c1C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050171130A1,CC#CCO.CCC(C)C(C)O.Clc1cc(Cl)ncn1>>CC#CCOc1cc(OC(C)C(C)CC)ncn1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20080045521A1,CN(C(=O)OC(C)(C)C)c1cccc(CCCc2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)OC(C)(C)C)cn2)n1>>CNc1cccc(CCCc2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cn2)n1,,O=C(O)C(F)(F)F,,,,test
US20100216788A1,CC(=O)c1cccc(Oc2ccc(N)cc2Cl)c1.O=C(OCCOCCn1ccc2ncnc(Cl)c21)c1ccccc1>>CC(=O)c1cccc(Oc2ccc(Nc3ncnc4ccn(CCOCCOC(=O)c5ccccc5)c34)cc2Cl)c1,,CC(C)O,,O=C([O-])O.[Na+],,test
US20120157487A1,ClCc1ncccn1.Nc1cc(Cl)ccc1S>>Nc1cc(Cl)ccc1SCc1ncccn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030087918A1,CCOC(CSC(=O)c1ccccc1)OCC>>CCOC(CS)OCC,,C1CCOC1,O,[Na+].[OH-],,test
US20030083315A1,CCOC(=O)CCCSc1nc2ccccc2[nH]1.ClCc1cccc2ccccc12>>CCOC(=O)CCCSc1nc2ccccc2n1Cc1cccc2ccccc12,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20070219216A1,C=CC#N.CC(C)Oc1ccc(F)cc1N1CCNCC1>>CC(C)Oc1ccc(F)cc1N1CCN(CCC#N)CC1,,CO,,,,test
US20110318388A1,CC(C)Br.Nc1ccc(F)cc1>>CC(C)Nc1ccc(F)cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20050026990A1,O=C1C[C@@H](NS(=O)(=O)c2ccc(-c3ccccc3)cc2)C(=O)N1OCc1ccccc1>>O=C1C[C@H](NS(=O)(=O)c2ccc(-c3ccccc3)cc2)C(=O)N1O,[Pd],CCO,,,,test
US20080181866A1,COc1ccc([C@@H]2NC(C(=O)O)CS2)cc1.O=C(Cl)OCc1ccccc1>>COc1ccc([C@H]2SCC(C(=O)O)N2C(=O)OCc2ccccc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20090318465A1,O=[N+]([O-])c1cnc(Cl)c(Cl)c1.Oc1cc2ccccc2cn1>>O=[N+]([O-])c1cnc(Oc2cc3ccccc3cn2)c(Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150148375A1,Nc1cc(Oc2ccc(F)cc2F)c(Br)cc1[N+](=O)[O-].O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1cc(Oc2ccc(F)cc2F)c(Br)cc1[N+](=O)[O-])C(F)(F)F,,ClCCl,O,CCN(CC)CC,,test
US04399210,NO.O=C1OC(=O)C2C3C=CC(C3)C12>>O=C(O)C1C2C=CC(C2)C1C(O)=NO,,O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20150165063A1,CC(=O)OC(C)=O.COc1cc(C(=O)N2CCC[C@H]2CO)c(NC(=O)OC(C)(C)C)cc1OCCCCCC(=O)OCC(Cl)(Cl)Cl>>COc1cc(C(=O)N2CCC[C@H]2COC(C)=O)c(NC(=O)OC(C)(C)C)cc1OCCCCCC(=O)OCC(Cl)(Cl)Cl,,CCOC(C)=O,ClCCl,CCN(CC)CC,CO,test
US05908919,ClCCNCCCl.O=C(Cl)OCCBr>>O=C(OCCBr)N(CCCl)CCCl,,ClCCl,,CCN(CC)CC,Cl,test
US20160222033A1,CCC(=O)c1nc(N)sc1I.CCOC(=O)N1C(=O)c2ccccc2C1=O>>CCC(=O)c1nc(N2C(=O)c3ccccc3C2=O)sc1I,,ClCCl,,CCN(CC)CC,,test
US20070004675A1,CCn1cc(-c2cc3nccc(Cl)c3s2)nc1C=O.CNC>>CCn1cc(-c2cc3nccc(Cl)c3s2)nc1CN(C)C,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US04863482,COc1cc(N)c([N+](=O)[O-])c(N)c1>>Nc1cc(O)cc(N)c1[N+](=O)[O-],,Br,,O,,test
US04055597,CCCCCC(CCCC(CCCCCCC(=O)OCC)C(N)=O)OC(C)=O>>CCCCCC(O)CCCC(CCCCCCC(=O)O)C(N)=O,,CO,O,[Na+].[OH-],,test
US04261997,Cn1c2ccc(Cl)cc2c(=O)n2nc(C(N)=O)cc12>>Cn1c2ccc(Cl)cc2c(=O)n2nc(C#N)cc12,,CN(C)C=O,,O=S(Cl)Cl,,test
US20150225381A1,CC(=O)N(C)C.CC(C)(C#N)Nc1ccc(O)c(F)c1.Cc1cc(N=C=S)ccc1C#N>>Cc1cc(N2C(=O)C(C)(C)N(c3ccc(O)c(F)c3)C2=S)ccc1C#N,,CC(=O)N(C)C,O,CO,Cl,test
US20130289020A1,CC(C)(C)OC(=O)N1CCOCC1CC(=O)O.c1ccc(CN2CCCNCC2)cc1>>CC(C)(C)OC(=O)N1CCOCC1CC(=O)N1CCCN(Cc2ccccc2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110110889A1,C=Cc1cn(S(=O)(=O)c2ccccc2)c2ncc(NC(=O)c3c(F)ccc(NS(=O)(=O)CCC)c3F)cc12>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]cc(CC)c3c2)c1F,[Pd],CO,,O,O=C([O-])[O-].[K+].[K+],test
US20100048610A1,CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1Oc1cc(C(=O)OC)c(I)cn1>>CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1Oc1cc(C(=O)O)c(I)cn1,,CO,,Cl,[Na+].[OH-],test
US20080194549A1,COCCCOc1cc(C(=O)OC)ccc1OC>>COCCCOc1cc(C(=O)O)ccc1OC,,CO,,[Na+].[OH-],,test
US20150225452A1,CN(Cc1ccccc1)[C@@H]1CCCc2ccccc21>>CN[C@@H]1CCCc2ccccc21,[Pd],CCOC(C)=O,CO,,,test
US20110105462A1,C1CNC1.Cc1ccc(S(=O)(=O)OCC2COc3c(F)cc(F)cc3O2)cc1>>Fc1cc(F)c2c(c1)OC(CN1CCC1)CO2,,CC#N,,,,test
US20090093480A1,CN(c1ccc(OC(F)(F)F)cc1)c1cc(C(F)(F)F)nc(Cl)n1.CNN>>CN(c1ccc(OC(F)(F)F)cc1)c1cc(C(F)(F)F)nc(NN)n1,,C1CCOC1,,,,test
US20110130445A1,Cc1c(N)cccc1Br.O=C1CCC(=O)N1Cl>>Cc1c(Br)ccc(Cl)c1N,,CC#N,,,,test
US20090186905A1,CCc1ccc(N=C=O)cc1.NCc1nc(C(=O)NCCc2cccc(Cl)c2)cs1>>CCc1ccc(NC(=O)NCc2nc(C(=O)NCCc3cccc(Cl)c3)cs2)cc1,,CN(C)C=O,,,,test
US20110190258A1,CC(C)(C)OC(=O)N1CC(C(=O)O)C1.CO.Cl>>COC(=O)C1CNC1.Cl,,CO,,C1COCCO1,,test
US20130029973A1,CCOC(=O)C1(N(C(C)C)S(=O)(=O)c2cccc(C(=O)Nc3sc4c(c3C(=O)Nc3ccc(CCc5ccc(C(=O)OC)cc5)cc3)CCCC4)c2)CC1>>CCOC(=O)C1(N(C(C)C)S(=O)(=O)c2cccc(C(=O)Nc3sc4c(c3C(=O)Nc3ccc(CCc5ccc(C(=O)O)cc5)cc3)CCCC4)c2)CC1,,CCO,,[Na+].[OH-],,test
US20120115850A1,COc1cc(OC)cc(C(C)N)c1.O=[N+]([O-])c1ccc(F)cc1F>>COc1cc(OC)cc(C(C)Nc2cc(F)ccc2[N+](=O)[O-])c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20100137299A1,COc1cc2c(cc1C)C1(CO2)C(=O)Nc2ccccc21>>COc1cc2c(cc1C)[C@@]1(CO2)C(=O)Nc2ccccc21,,COC(C)(C)C,,CC#N,,test
US04337260,NC(=O)C1(N2CCCCC2)CCN(Cc2ccccc2)CC1>>O=C1N=C2CCCCN2C12CCNCC2,[Pd],Cc1ccccc1,,O,,test
US20100197683A1,CC(=O)OC(O)CO.CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(C2CCC(=O)CC2)c2ncnn12>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(C2CCC3(CC2)OCC(CO)O3)c2ncnn12,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20130289027A1,COC(=O)C(OC(C)(C)C)c1c(-c2ccc3c(c2C)CCCO3)c2ccc(O)cc2c(=O)n1C.OCCCBr>>COC(=O)C(OC(C)(C)C)c1c(-c2ccc3c(c2C)CCCO3)c2ccc(OCCO)cc2c(=O)n1C,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20090270450A1,CCOc1cc2ncc(C(N)=O)c(Nc3ccc(F)cc3F)c2cc1Br.OB(O)c1cccnc1>>CCOc1cc2ncc(C(N)=O)c(Nc3ccc(F)cc3F)c2cc1-c1cccnc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140343295A1,CC(C)(C)OC(=O)N1CC2C(C1)C2C(N)=O.Cl>>Cl.NC(=O)C1C2CNCC21,,CO,,ClCCl,,test
US20090137595A1,Cc1cc(N)n(C)n1.Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1N.O=C(n1ccnc1)n1ccnc1>>Cc1cc(NC(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)ccc2C)n(C)n1,,CN(C)C=O,,O,,test
US20100113502A1,CC(C)N1CCc2[nH]c3ccc(C(=O)O)cc3c2C1.CCOC1CCNCC1>>CCOC1CCN(C(=O)c2ccc3[nH]c4c(c3c2)CN(C(C)C)CC4)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04956465,CCOC(=O)c1cn(C2CC2)c2c(F)c(C(C#N)C(=O)OCC)c(F)cc2c1=O>>N#CCc1c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c2c1F,,O,,CC(=O)O,O=S(=O)(O)O,test
US20040005649A1,COCOCCOCCOCc1ccc(/C=C/c2ccccc2)cc1>>OCCOCCOCc1ccc(/C=C/c2ccccc2)cc1,,CO,,Cl,,test
US20050192300A1,CN1CCNCC1.COc1ccc(Nc2nccc(-c3sc(NC(=O)CCBr)nc3C)n2)cc1>>COc1ccc(Nc2nccc(-c3sc(NC(=O)CCN4CCN(C)CC4)nc3C)n2)cc1,,CC#N,,,,test
US20140364412A1,Nc1ccc(F)c(CC(=O)O)c1>>Nc1ccc(F)c(CCO)c1,,C1CCOC1,,,,test
US20140296304A1,Fc1cc(I)ccn1.Nc1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(Nc2cc(I)ccn2)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070232583A1,Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)Cl)c3)n2)n1.O=S1(=O)CCNCC1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)N4CCS(=O)(=O)CC4)c3)n2)n1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20070287701A1,COc1ccc2nccc(CCN3CC[C@@H](CN)C3)c2n1.O=Cc1ccc2c(n1)NC(=O)CS2>>COc1ccc2nccc(CCN3CC[C@@H](CNCc4ccc5c(n4)NC(=O)CS5)C3)c2n1,,CCO,ClCCl,[BH4-].[Na+],,test
US04731368,COc1cnc2cc(S(N)(=O)=O)sc2c1>>NS(=O)(=O)c1cc2ncc(O)cc2s1,,O,,Cl,c1ccncc1,test
US20140163026A1,COC(=O)c1ccc(Br)cc1Cl.O=[N+]([O-])O>>COC(=O)c1cc([N+](=O)[O-])c(Br)cc1Cl,,O=S(=O)(O)O,,,,test
US20160016895A1,COC(=O)C(C)(CCc1ccc(C#CC#C[C@@H]2C[C@H]2CO)cc1)S(C)(=O)=O.NO>>CC(CCc1ccc(C#CC#C[C@@H]2C[C@H]2CO)cc1)(C(=O)NO)S(C)(=O)=O,,CC(C)O,,CC(=O)O,,test
US04243677,CC(C)=CCCl.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CC(C)=CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Cl-],,Cc1ccccc1,,,,test
US20120010191A1,CC(C)(C)[Si](C)(C)OCCn1cc(N)cn1.Cn1cc(Br)nc(Br)c1=O>>Cn1cc(Br)nc(Nc2cnn(CCO)c2)c1=O,,CC(C)O,,,,test
US20030125370A1,O=C(NC1CC1)[C@@H]1CCCN1>>C1CN[C@H](CNC2CC2)C1,,C1CCOC1,,Cl,,test
US20110015196A1,CC(C)(C)OC(=O)N[C@@H]1C[C@H](C(=O)N2CCCC2)C1(C)C>>CC1(C)[C@H](N)C[C@@H]1C(=O)N1CCCC1,,ClCCl,O=C(O)C(F)(F)F,CCN(CC)CC,,test
US04988689,N#CCN1CCC(Nc2nc3ccccc3n2Cc2ccccn2)C1>>NCCN1CCC(Nc2nc3ccccc3n2Cc2ccccn2)C1,[Ni],CO,,N,[H][H],test
US20150351401A1,O=C(O)C1(Cl)CC1.Oc1c(F)c(F)c(F)c(F)c1F>>O=C(Oc1c(F)c(F)c(F)c(F)c1F)C1(Cl)CC1,CN(C)c1ccncc1,ClCCl,O,,,test
US20120184565A1,C=CCOc1cc([N+](=O)[O-])ccc1C#N>>C=CCOc1cc(N)ccc1C#N,[Fe],O,,CO,[Cl-].[NH4+],test
US20080293712A1,CC(C)(C)OC(=O)N1CCC[C@@H](Oc2cncc(C(=O)n3ccnc3)c2)C1.COc1cc2ncc(C#N)c(C)c2cc1OC>>COc1cc2ncc3c(N)nc(-c4cncc(O[C@@H]5CCCN(C(=O)OC(C)(C)C)C5)c4)cc3c2cc1OC,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20060160821A1,Cc1ccccc1C(NC(=O)Nc1ccc(Cl)cc1)C(=O)O.Nc1ccc(C(=O)N2CCSC2)cc1>>Cc1ccccc1C(NC(=O)Nc1ccc(Cl)cc1)C(=O)Nc1ccc(C(=O)N2CCSC2)cc1,,CN(C)C=O,,ClCCCl,,test
US20060154917A1,CCCCn1c(-c2c(C)cccc2C)nc(Cl)c1C=O>>CCCCn1c(-c2c(C)cccc2C)nc(Cl)c1CO,,CO,,[BH4-].[Na+],,test
US20110092526A1,COC(=O)c1cnc(N[C@H]2CCOC2)nc1C1CCC1>>O=C(O)c1cnc(N[C@H]2CCOC2)nc1C1CCC1,,CO,,[Na+].[OH-],,test
US20120184546A1,Nc1ccccc1C(=O)O.O=C(Cl)Cc1ccc([N+](=O)[O-])cc1>>O=C(Cc1ccc([N+](=O)[O-])cc1)Nc1ccccc1C(=O)O,,ClCCl,,c1ccncc1,,test
US20110144100A1,CC(C)(C)OC(=O)NCC1CCN(c2cccc3ccc(C=O)nc23)CC1.NNc1cc(I)ccn1>>CC(C)(C)OC(=O)NCC1CCN(c2cccc3ccc(/C=N/Nc4cc(I)ccn4)nc23)CC1,,ClCCl,,,,test
US20090042859A1,CS(=O)(=O)N1CC2(CCNC2)c2cc(Cl)ccc21.ClCC=Cc1ccc(Cl)cc1>>CS(=O)(=O)N1CC2(CCN(C/C=C/c3ccc(Cl)cc3)C2)c2cc(Cl)ccc21,,CC#N,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20040266839A1,Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)O)cc3)c2)o1.N#Cc1cccc(N)c1>>Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)Nc4cccc(C#N)c4)cc3)c2)o1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US06962926B2,Cc1nn(C)c2nc(CCN3CCCC3)c(C#N)cc12.O=S(=O)(O)O>>Cc1nn(C)c2nc(CCN3CCCC3)c(C(N)=O)cc12,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20090264445A1,CC(C)(O)Cn1ccc(N)n1.COC1=CC(=O)N([C@@H](CC2CCCC2)C(=O)O)C1>>COC1=CC(=O)N([C@@H](CC2CCCC2)C(=O)Nc2ccn(CC(C)(C)O)n2)C1,CN(C)C=O,ClCCl,c1ccccc1,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US05661169,CCC(C)(C)N.O=S(=O)(Cl)c1ccc(CBr)cc1>>CCC(C)(C)NS(=O)(=O)c1ccc(CBr)cc1,,Cc1ccccc1,,CCN(CC)CC,O,test
US20070032653A1,CC(C)CCCC(NC(=O)OC(C)(C)C)c1nc(-c2cccc(Br)c2)c[nH]1>>CC(C)CCCC(N)c1nc(-c2cccc(Br)c2)c[nH]1,,CCOC(C)=O,Cl,,,test
US20150119412A1,CC(C)(C)OC(=O)N1CCC(n2ccc(OCc3ccccc3)cc2=O)CC1.O=C1CCC(=O)N1I>>CC(C)(C)OC(=O)N1CCC(n2ccc(OCc3ccccc3)c(I)c2=O)CC1,,CC(=O)O,,O=C([O-])O.[Na+],,test
US20120329818A1,CC(C)(C)OC(=O)N1CCC(C)(C(=O)O)CC1>>CC1(C(=O)O)CCNCC1,,C1COCCO1,,Cl,,test
US20110065681A1,CO.O=C(O)c1cc(Br)cc(Br)c1>>COc1cc(Br)cc(C(=O)O)c1,[Cu]Br,CN(C)C=O,,Cl,C[O-].[Na+],test
US20090012118A1,O=C(O)c1cc(=O)c2cc(O)ccc2[nH]1.c1ccc(CC2CCNCC2)cc1>>O=C(c1cc(=O)c2cc(O)ccc2[nH]1)N1CCC(Cc2ccccc2)CC1,,CCOCC,,,,test
US20150258074A1,COc1ccc(CN(Cc2ccc(OC)cc2)[C@@H](c2ccccc2)C(C)(C)OC)cc1>>COC(C)(C)[C@@H](N)c1ccccc1,[Pd],CO,,,,test
US20090247502A1,NCC(=O)c1ccccc1.O=C(Cl)c1cnc2c(c1)N(S(=O)(=O)c1ccc(C(F)(F)F)cc1)CCO2>>O=C(CNC(=O)c1cnc2c(c1)N(S(=O)(=O)c1ccc(C(F)(F)F)cc1)CCO2)c1ccccc1,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20080085884A1,CC(C)(C)[Si](C)(C)O[C@@H]1CCN(c2ccc(-n3ccc(O)cc3=O)cn2)C1.O=S(=O)(Cl)c1ccc(Br)cc1>>CC(C)(C)[Si](C)(C)O[C@@H]1CCN(c2ccc(-n3ccc(OS(=O)(=O)c4ccc(Br)cc4)cc3=O)cn2)C1,,ClCCl,,CCN(CC)CC,O=C([O-])[O-].[K+].[K+],test
US20070259879A1,Cc1cc(Br)ccc1C(=O)C(=O)N1CCN(C(=O)c2ccccc2)C[C@H]1C.OB(O)c1cc[nH]n1>>Cc1cc(-c2cc[nH]n2)ccc1C(=O)C(=O)N1CCN(C(=O)c2ccccc2)C[C@H]1C,,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20040049037A1,COc1cccc(C(=O)NC(C)(CO)C(C)C)c1C>>COc1cccc(C(=O)NC(C)(C=O)C(C)C)c1C,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US05750754,O=C(O)C1(O)C=CC(c2ccccc2)=CC1>>OCC1(O)C=CC(c2ccccc2)=CC1,,O,,CCOC(C)=O,Cl,test
US20100234367A1,C[C@H]1COc2c(F)c(F)c(N)c3c(=O)c(C#N)cn1c23.N[C@H]1CC[C@@H](c2ccccn2)C1>>C[C@H]1COc2c(N[C@H]3CC[C@@H](c4ccccn4)C3)c(F)c(N)c3c(=O)c(C#N)cn1c23,,CS(C)=O,,CCN(CC)CC,,test
US20030153564A1,CC(C)(C)OC(=O)N[C@H](COc1ccc(C#N)cc1)CN1CC2CN(C(=O)OCc3ccccc3)CC(C1)O2>>CC(C)(C)OC(=O)N[C@H](COc1ccc(C#N)cc1)CN1CC2CNCC(C1)O2,[Pd],CCO,,[H][H],,test
US20150175628A1,COC(=O)c1ccc(Br)cc1C.NN>>NNC(=O)c1ccc(Br)cc1,,CO,,O,,test
US20150336944A1,CC(C)(C)OC(=O)N(c1nccs1)S(=O)(=O)c1cc(Cl)c(Oc2cnc(Cl)cc2-c2cccnc2)cc1F.OB(O)c1cccc(F)c1>>O=S(=O)(Nc1nccs1)c1cc(Cl)c(Oc2cnc(-c3cccc(F)c3)cc2-c2cccnc2)cc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,O=C([O-])[O-].[Na+].[Na+],test
US04985444,CCOC(=O)CCCBr.O=c1ccc(-c2c(-c3ccccc3)nn3ccccc23)n[nH]1>>CCOC(=O)CCCn1nc(-c2c(-c3ccccc3)nn3ccccc23)ccc1=O,,ClC(Cl)Cl,,,,test
US20150126490A1,CC(C)(C)OC(=O)c1ccc(-c2nc(C3CCC(OC(=O)c4ccccc4)C(F)(F)C3)cnc2N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc1F>>Nc1ncc(C2CCC(OC(=O)c3ccccc3)C(F)(F)C2)nc1-c1ccc(C(=O)O)c(F)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06756373B1,CC(N)=NO.CCCc1c2nc(-c3cc(I)cnc3OCC(C)C)[nH]c(=O)c2nn1C.[C]=O>>CCCc1c2nc(-c3cc(-c4nc(C)no4)cnc3OCC(C)C)[nH]c(=O)c2nn1C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,Cc1ccccc1,CCN(CC)CC,,test
US04816454,CC(CC(=O)O)C(=O)c1ccc(Cc2cccnc2)cc1.Cl.NN>>CC1CC(=O)NN=C1c1ccc(Cc2cccnc2)cc1.Cl,,COCCO,,O,,test
US20130116235A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1nc([N+](=O)[O-])cn1C>>Cc1nc(NC(=O)OC(C)(C)C)cn1C,[Pd],CCO,,CCN(CC)CC,,test
US05468748,O=c1[nH]c2c([nH]c1=O)C(Cl)c1ccccc1-2.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>O=c1[nH]c2c([nH]c1=O)C(N1CCN(C(c3ccccc3)c3ccccc3)CC1)c1ccccc1-2,,C1CCOC1,,CCN(CC)CC,,test
US04096144,CCI.Nc1ccc(Cl)cc1C(=O)c1ccccc1>>CCNc1ccc(Cl)cc1C(=O)c1ccccc1,,O,,[H-].[Na+],,test
US20090088426A1,COC[C@H](C)COCc1ccc(C2(O)CCN(Cc3ccccc3)CC2COC(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>COC[C@H](C)COCc1ccc(C2=CCN(Cc3ccccc3)CC2COC(c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,c1ccncc1,,O=S(Cl)Cl,,test
US20110257198A1,CCOc1c([N+](=O)[O-])cc(C)nc1C(=O)O.CO.O=C(Cl)C(=O)Cl>>CCOc1c(Cl)cc(C)nc1C(=O)OC,CN(C)C=O,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US03974179,CCOC(=O)CC(C)=O.OCCc1c[nH]c2ccccc12>>CCOC(=O)CC1(C)OCCc2c1[nH]c1ccccc21,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US06586441B2,CS(=O)c1nc(N)nc(-c2ccccn2)c1C#N.SCCc1ccccn1>>N#Cc1c(SCCc2ccccn2)nc(N)nc1-c1ccccn1,,COCCOC,,C1CCC2=NCCCN2CC1,,test
US20100331365A1,CN1CCC(Cl)CC1.COC(=O)CSc1ccc2c(c1)C(=O)c1sccc1CO2>>COC(=O)CSc1ccc2c(c1)C(O)(C1CCN(C)CC1)c1sccc1CO2,,C1CCOC1,,[Mg],[Cl-].[NH4+],test
US20130059832A1,C=CCBr.C=CCC(O)COCc1ccccc1>>C=CCOC(CC=C)COCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US05538988,C=CC(=O)OCC.S=c1[nH]ccn1C1CCc2ccccc2C1>>CCOC(=O)CCSc1nccn1C1CCc2ccccc2C1,,CCO,,Cl,,test
US05378715,CCOCC.COC(=O)c1cccc2c(S(=O)(=O)Nc3onc(C)c3C)cccc12.C[Mg]Br>>Cc1noc(NS(=O)(=O)c2cccc3c(C(C)(C)O)cccc23)c1C,,C1CCOC1,,,,test
US20080004391A1,N#Cc1ccc([N+](=O)[O-])cc1C#N.Oc1ccc(-c2ccccc2)cc1>>N#Cc1ccc(Oc2ccc(-c3ccccc3)cc2)cc1C#N,,Cl,,O=C([O-])[O-].[K+].[K+],,test
US05856274,CSSC.Cc1ccc(Cl)c(N)c1Cl>>CSc1c(Cl)ccc(C)c1Cl,[Cu],CC(=O)O,O,Cl,O=N[O-].[Na+],test
US20100288974A1,CC(=O)O.C[Mg]Cl.O=C1C(=O)c2ccc(Br)cc2-c2cc(Br)ccc21>>CC1(O)c2ccc(Br)cc2-c2cc(Br)ccc2C1(C)O,,C1CCOC1,CCOC(C)=O,,,test
US03941803,O=C(c1ccccc1Cl)c1cc(Cl)ccc1-n1ccnc1CN1C(=O)c2ccccc2C1=O>>Clc1ccc2c(c1)C(c1ccccc1Cl)=NCc1nccn1-2,,CCO,,NN,O,test
US20140088101A1,COC(=O)c1ncc2c(cc(-c3ccccc3C(F)(F)F)c(=O)n2Cc2ccccc2)c1O.O=C1CCC(=O)N1Br>>COC(=O)c1nc(Br)c2c(cc(-c3ccccc3C(F)(F)F)c(=O)n2Cc2ccccc2)c1O,,ClCCl,,,,test
US04029670,COC(=O)c1ccc2oc(-c3ccc(C)cc3)nc2c1>>Cc1ccc(-c2nc3cc(C(=O)O)ccc3o2)cc1,,O,,CCO,[Na+].[OH-],test
US20140296208A1,COc1c(N)cc(C(C)(C)C)cc1C(N)=O.COc1cc(Nc2cc(Oc3ccc(NC(=O)Oc4ccccc4)c4ccccc34)ccn2)cc(C(=O)NCCN2CCOCC2)c1>>COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)cc(C(N)=O)c4OC)c4ccccc34)ccn2)cc(C(=O)NCCN2CCOCC2)c1,,CC(=O)OC(C)C,,CCN(CC)CC,CN(C)C=O,test
US20060287300A1,CC(=O)OC(C)=O.CONC1(CCC(C)C)C(=O)C(C2=NS(=O)(=O)c3cc(NC(=O)OC(C)(C)C)ccc3N2)=C(O)c2ccccc21>>CON(C(C)=O)C1(CCC(C)C)C(=O)C(C2=NS(=O)(=O)c3cc(NC(=O)OC(C)(C)C)ccc3N2)=C(O)c2ccccc21,,c1ccncc1,,,,test
US20120269738A1,COCCOCCn1c2ccccc2c2cc(C=O)ccc21.Cc1cc[n+](CCO)cc1.[Cl-]>>COCCOCCn1c2ccccc2c2cc(/C=C/c3cc[n+](CCO)cc3)ccc21.[Cl-],,CCO,,C1CCNCC1,,test
US20030069246A1,CC(=O)C(C#N)c1c(C)cc(Cl)cc1C.NN>>Cc1cc(Cl)cc(C)c1-c1c(C)n[nH]c1N,,Cc1ccccc1,,CC(=O)O,,test
US20040019058A1,C=COC(=O)Cl.OCC1CCN(Cc2ccccc2)C1>>C=COC(=O)OCC1CCN(Cc2ccccc2)C1,,ClCCCl,,,,test
US20090170903A1,COc1ccc(C(=O)Cl)c2c1oc1ccc([N+](=O)[O-])cc12.Cc1c(Cl)cncc1Cl>>COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)c2c1oc1ccc([N+](=O)[O-])cc12,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20160221973A1,COC(=O)c1ccc2c(c1)OC[C@H](c1ccccc1)NC2.O=C(Cl)N1CCOCC1>>COC(=O)c1ccc2c(c1)OC[C@H](c1ccccc1)N(C(=O)N1CCOCC1)C2,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20070191333A1,CCC1(O)CN(C(c2ccccc2)c2ccccc2)C1.CS(=O)(=O)Cl>>CCC1(OS(C)(=O)=O)CN(C(c2ccccc2)c2ccccc2)C1,,ClCCl,,CCN(CC)CC,,test
US20010034343A1,CCOCCn1c(N2CCCN(CC[C@]3(c4ccccc4)CCN(C(=O)c4cc(O)ccc4OC)C3)CC2)nc2ccccc21.CS(=O)(=O)Cl>>CCOCCn1c(N2CCCN(CC[C@]3(c4ccccc4)CCN(C(=O)c4cc(OS(C)(=O)=O)ccc4OC)C3)CC2)nc2ccccc21,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080269211A1,COC(=O)C[C@@H]1C[C@H](NC(=O)c2nn(C(C)C)c3ccccc23)CN1C(=O)OC(C)(C)C>>CC(C)n1nc(C(=O)N[C@H]2C[C@@H](CCO)N(C(=O)OC(C)(C)C)C2)c2ccccc21,,C1CCOC1,,O,[BH4-].[Li+],test
US20140206681A1,COC(=O)[C@H]1CC[C@H]2CCN(Cc3ccc(OC)cc3OC)C(=O)N2C1>>COC(=O)[C@H]1CC[C@H]2CCNC(=O)N2C1,,O=C(O)C(F)(F)F,,,,test
US04260612,CCOC(=O)c1cnc2n(c1=O)C(C)CCC2Br.CNc1ccccc1>>CCOC(=O)c1cnc2n(c1=O)C(C)CCC2N(C)c1ccccc1,,ClCCl,,CCO,Cl,test
US20040048908A1,COC(=O)CCc1cnoc1-c1ccc(OC)c(OC)c1>>COc1ccc(-c2oncc2CCCO)cc1OC,,C1CCOC1,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20080175814A1,O=[N+]([O-])c1cccc(Nc2ccncc2)c1>>Nc1cccc(Nc2ccncc2)c1,[Pd],CO,,,,test
US20070161681A1,CC(O)C#N.O=C(NCc1ccc(O)cc1F)c1cccnc1Oc1ccc2c(c1)OCO2>>CC(C#N)Oc1ccc(CNC(=O)c2cccnc2Oc2ccc3c(c2)OCO3)c(F)c1,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090209552A1,CCOP(=O)(CC#N)OCC.O=Cc1cc(Cl)cc([N+](=O)[O-])c1>>N#CC=Cc1cc(Cl)cc([N+](=O)[O-])c1,,C1CCOC1,,[H-].[Na+],,test
US20010021718A1,C[Si](C)(C)ON.NC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)O)n1>>NC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)NO)n1,,C1CCOC1,CO,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20040082625A1,COc1ccc(-c2cc(CO)ccc2OC)cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COc1ccc(-c2cc(CN=[N+]=[N-])ccc2OC)cc1,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20150148340A1,O=C1CCc2c1cccc2C(F)(F)F>>O[C@H]1CCc2c1cccc2C(F)(F)F,,ClCCl,,CCN(CC)CC,O=CO,test
US20110059968A1,NC(=O)C(=O)C(Cc1ccc(F)cc1)NC(=O)c1cccnc1-n1ccc(-c2ccc(Cl)cc2Cl)n1.OCCBr>>NC(=O)C1(C(Cc2ccc(F)cc2)NC(=O)c2cccnc2-n2ccc(-c3ccc(Cl)cc3Cl)n2)OCCO1,,CN(C)C=O,,C1CCC2=NCCCN2CC1,O,test
US04073917,CC(C)COc1ccccc1O.CC(C)N(CCCl)C(C)C>>CC(C)COc1ccccc1OCCN(C(C)C)C(C)C,,CCO,,Cl,[Na],test
US20150266857A1,CC(C)(C)OC(=O)N1CCC(c2nc3ccc(-c4cn(S(=O)(=O)c5ccccc5)c5cc(F)ccc45)cc3o2)CC1>>CC(C)(C)OC(=O)N1CCC(c2nc3ccc(-c4c[nH]c5cc(F)ccc45)cc3o2)CC1,,CO,,[Na+].[OH-],,test
US20120040954A1,C1CCNC1.COc1cc(OC)c2c(=O)[nH]c(-c3ccc4[nH]c(CCBr)cc4c3)nc2c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc4[nH]c(CCN5CCCC5)cc4c3)nc2c1,,CN(C)C=O,,,,test
US20040147612A1,CCOC(=S)[S-].N#CCc1ccc(N)cc1>>CCOC(=S)Sc1ccc(CC#N)cc1,,Cl,O,O=N[O-].[Na+],,test
US20060074111A1,CCOC(=O)COc1ccc(CN(CCC2CC2)c2cccc(-c3ccc(C(F)(F)F)cc3)c2)cc1C>>Cc1cc(CN(CCC2CC2)c2cccc(-c3ccc(C(F)(F)F)cc3)c2)ccc1OCC(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20140206681A1,CC(C)(C)OC(=O)Nc1cc(C(F)F)ccn1>>Nc1cc(C(F)F)ccn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090075989A1,COC(=O)c1ccc(CC(O)(C(=O)Nc2ccc(C#N)c(Cl)c2)c2ccccc2)cc1>>N#Cc1ccc(NC(=O)C(O)(Cc2ccc(CO)cc2)c2ccccc2)cc1Cl,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20160106754A1,CC(=O)NN1C(=O)CC(=O)CC12CCOCC2.Nc1ccc(OC(F)(F)F)cc1SSc1cc(OC(F)(F)F)ccc1N>>CC(=O)NN1C(=O)C2=C(CC13CCOCC3)Nc1ccc(OC(F)(F)F)cc1S2,CCN(CC)CC,CCO,,,,test
US20040180912A1,COc1cccc(C(=O)c2ccc(C(C)C)cc2)c1[N+](=O)[O-]>>COc1cccc(C(=O)c2ccc(C(C)C)cc2)c1N,[Ni],C1CCOC1,CO,,,test
US20120115844A1,Cc1nnn(-c2ccc(F)cc2)c1CO.Clc1ccc(Cl)nn1>>Cc1nnn(-c2ccc(F)cc2)c1COc1ccc(Cl)nn1,,C1CCOC1,,[H-].[Na+],,test
US20050159424A1,Cc1c(C(=O)O)cnn1-c1ccccc1.O=S(=O)(Cl)Cl>>Cc1c(C(=O)Cl)cnn1-c1ccccc1,,ClCCl,,CN(C)C=O,,test
US20100008866A1,Cc1csc(C(=O)Nc2ccc(Cl)nc2)c1NC(=O)C1CCC(C(F)(F)F)CC1>>Cc1csc2c(=O)n(-c3ccc(Cl)nc3)c([C@H]3CC[C@@H](C(F)(F)F)CC3)nc12,,O=P(Cl)(Cl)Cl,,,,test
US20080009482A1,COc1cc(F)ccc1[N+](=O)[O-].NCCN1CCCC1>>COc1cc(NCCN2CCCC2)ccc1N,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,,test
US20130116246A1,CC(C)(C)OC(=O)Nc1cc2n(n1)CCC2>>Nc1cc2n(n1)CCC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060079503A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(O)cc1>>CC(C)(C)OC(=O)c1ccc(O)cc1,,ClCCl,,CC(C)NC(C)C,,test
US20120142706A1,Cc1ccnc(Cl)c1.OO>>Cc1cc[n+]([O-])c(Cl)c1,,CC(=O)O,,O=C([O-])[O-].[Na+].[Na+],,test
US20030144333A1,CCOC(=O)C(=O)c1cc(Br)sc1Br>>O=C(O)C(=O)c1cc(Br)sc1Br,,CC(C)=O,O,Cl,,test
US20100174073A1,COc1cc2nc(N(C)CCC#N)nc(N)c2cc1OC.N>>COc1cc2nc(N(C)CC(C)N)nc(N)c2cc1OC,[Ni],,,Cl,,test
US20160009744A1,CC(C)(C)[Si](C)(C)Cl.O=C1OCC(O)c2ccccc21>>CC(C)(C)[Si](C)(C)OC1COC(=O)c2ccccc21,,ClCCl,,c1c[nH]cn1,,test
US20040198778A1,NC(CO)C(C(F)(F)F)C(F)(F)F.O=S(=O)(Cl)c1cc(Cl)c(Cl)s1>>O=S(=O)(NC(CO)C(C(F)(F)F)C(F)(F)F)c1cc(Cl)c(Cl)s1,,C1CCOC1,,c1ccncc1,,test
US20160222005A1,CC(C)(C)OC(=O)N1CC=C(c2cc(Cl)c([N+](=O)[O-])c(N)n2)CC1>>CC(C)(C)OC(=O)N1CCC(c2cc(Cl)c(N)c(N)n2)CC1,O=[Pt]=O,CCN(C(C)C)C(C)C,,CO,,test
US04895842,CC(C)(C)OC(=O)NC(Cc1ccc([N+](=O)[O-])cc1)C(=O)O.Nc1ccc(C(=O)c2ccccc2)cc1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NC1CCCCC1,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US05834412,Cc1c(-c2cccc(O)c2)oc2ccccc12.OCC1CO1>>Cc1c(-c2cccc(OCC(O)CO)c2)oc2ccccc12,,CO,,C[O-].[Na+],,test
US20100009950A1,BrCCCCCCOCCCCc1ccccc1.CC1(C)OCc2cc(C(O)CN)ccc2O1>>CC1(C)OCc2cc(C(O)CNCCCCCCOCCCCc3ccccc3)ccc2O1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US05556864,CCc1ccc(CCc2ccccc2OCCC2CCCCN2C(=O)OC(C)(C)C)cc1>>CCc1ccc(CCc2ccccc2OCCC2CCCCN2C)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080280950A1,CC[C@]1(CS(=O)(=O)Cl)NC(=O)NC1=O.FC(F)(F)COc1ccc(OC2CCNCC2)cc1>>CC[C@]1(CS(=O)(=O)N2CCC(Oc3ccc(OCC(F)(F)F)cc3)CC2)NC(=O)NC1=O,,ClCCl,,CCN(CC)CC,Cl,test
US07351826B2,CCCc1c(C)ncnc1Cl.NN>>CCCc1c(C)ncnc1NN,,CCO,,O,,test
US20090264406A1,Cn1cc(-c2ccc3ncc(Cc4ccc5ncc(C=O)n5c4)n3n2)cn1>>Cn1cc(-c2ccc3ncc(Cc4ccc5ncc(CO)n5c4)n3n2)cn1,,CO,,O,[BH4-].[Na+],test
US04962103,CC(=O)S[C@H]1C[C@@H](COC(=O)NC(=O)C(Cl)(Cl)Cl)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1>>NC(=O)OC[C@@H]1C[C@H](S)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1,,CO,,[Na+].[OH-],,test
US04402972,C=CC(C)(C)O.CC1(C)[C@@H](C#CC(=O)O)[C@H]1C(=O)O[C@H](C#N)c1cccc(Oc2ccccc2)c1>>C=CC(C)(C)OC(=O)C#C[C@H]1[C@@H](C(=O)O[C@H](C#N)c2cccc(Oc3ccccc3)c2)C1(C)C,CN(C)c1ccncc1,ClCCl,,,,test
US04034095,C=O.Cl.O=C(O)CC1CCNCC1Cc1ccccc1>>CN1CCC(CC(=O)O)C(Cc2ccccc2)C1.Cl,,O=CO,,Cl,N,test
US20150038488A1,COc1ccc([C@@H](C)N2C[C@H](C(=O)N(C)OC)CC2=O)cc1>>COc1ccc([C@@H](C)N2C[C@H](C=O)CC2=O)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US07919468B2,COC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)O,,C1CCOC1,,[Li+].[OH-],,test
US20060030613A1,CC(C)(C)c1ccc(CNCCc2cccc(Cl)c2F)cc1.O=C(O)c1cccc2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCc2cccc(Cl)c2F)C(=O)c2cccc3cc[nH]c23)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US05053422,CC(C)COC(=O)/C=C/C=O>>CC(C)COC(=O)CCC=O,[Pd],CCO,,,,test
US20040023971A1,CC(C)(C)OC(=O)N1C2CCC1CNC2.N#Cc1ccc(OCC2CO2)cc1>>CC(C)(C)OC(=O)N1C2CCC1CN(CC(O)COc1ccc(C#N)cc1)C2,,CC(C)O,,O,,test
US06034239,BrCBr.CCCC(=O)NCCC1CCc2ccc(O)c(O)c21>>CCCC(=O)NCCC1CCc2ccc3c(c21)OCO3,O=[Cu],CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US06313127B1,O=Cc1ccc(Oc2ccccc2)cc1.c1cc(N2CCNCC2)ccn1>>c1ccc(Oc2ccc(N3CCN(c4ccncc4)CC3)cc2)cc1,,CC(=O)O,ClCCl,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US03998955,CCCCc1cnc(CO)cc1OC.Cl>>CCCCc1cnc(CO)cc1OC.Cl,,CCOCC,CO,CC(C)=O,,test
US20070105913A1,CCCCc1ccc(C#Cc2ccc(CN(Cc3ccc(OCC(=O)OC)cc3)C(=O)c3n[nH]c4ccccc34)cc2)cc1>>CCCCc1ccc(C#Cc2ccc(CN(Cc3ccc(OCC(=O)O)cc3)C(=O)c3n[nH]c4ccccc34)cc2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20080207654A1,CCCCc1nc(CC2CC2)n(-c2ccc3c(c2)CCO3)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nc(CC2CC2)n(-c2ccc3c(c2)CCO3)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20150376225A1,CC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C>>CC(=O)C1CCC2C3CCC4CC(O)CCC4(C)C3C(O)CC12C,[Pd],CCO,,[H][H],,test
US20070225280A1,CC(C)(C)OCCBr.NN>>CC(C)(C)OCCNN,,CCO,,O,,test
US20030087957A1,CCOc1ccc(C=O)cc1.ONC1CCCC1>>CCOc1ccc(C=[N+]([O-])C2CCCC2)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04713457,CCc1nc(C)c[nH]1.Cc1ccc(S(=O)(=O)OC[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)cc1>>CCc1nc(C)cn1C[C@@H]1C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1,,CN(C)C=O,,[H-].[Na+],,test
US20160213653A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=Cc1cccc(-c2cnc3[nH]cc(I)c3c2)c1>>Cc1ccc(S(=O)(=O)n2cc(I)c3cc(-c4cccc(C=O)c4)cnc32)cc1,,C1CCOC1,,[H-].[Na+],,test
US20050197350A1,CCNc1ccnc(Cl)n1.N[C@@H]1CC[C@H](NC(=O)c2ccc(F)c(F)c2)CC1>>CCNc1ccnc(N[C@@H]2CC[C@H](NC(=O)c3ccc(F)c(F)c3)CC2)n1.Cl,,CCCCO,,O=C([O-])O.[Na+],,test
US20040254158A1,COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(C4(C(N)=O)CC4)cc2)CC3)cc1>>COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(C4(C#N)CC4)cc2)CC3)cc1,,CN(C)C=O,,O=S(Cl)Cl,,test
US20100305096A1,Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C=O)n(C)c2n1.O=C(C1CNC1)N1CCC1>>Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CC(C(=O)N4CCC4)C3)n(C)c2n1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20050070561A1,O=C(Nc1cccc(F)c1)c1cc([N+](=O)[O-])n[nH]1>>Nc1cc(C(=O)Nc2cccc(F)c2)[nH]n1,O=[Pt]=O,CCO,CCOC(C)=O,,,test
US06423689B1,CC(C)(C)N.CC(C)(C)OC(=O)N[C@@H](Cc1ccc([N+](=O)[O-])cc1)C(=O)O>>CC(C)(C)NC(=O)[C@H](Cc1ccc([N+](=O)[O-])cc1)NC(=O)OC(C)(C)C,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080242663A1,CI.O=CNc1cccc(COC=O)c1>>CN(C=O)c1cccc(COC=O)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090209648A1,CCNCC.Cc1ccc(Nc2ccc(Cl)c(C)c2Cl)c(CC(=O)O)c1>>CCNCC.Cc1ccc(Nc2ccc(Cl)c(C)c2Cl)c(CC(=O)O)c1,,COC(C)(C)C,,,,test
US20120053183A1,CC(C)(C)OC(=O)N1CCNCC1.CCc1ccnc(Cl)n1>>CCc1cnc(N2CCN(C(=O)OC(C)(C)C)CC2)nc1,,CCO,,CCN(CC)CC,,test
US20080081818A1,N#CSc1c(N)nc(C(F)(F)F)nc1O>>Nc1nc2nc(C(F)(F)F)nc(O)c2s1,,CCOC(C)=O,CN(C)C=O,,,test
US20130079324A1,Cc1n[nH]cc1[N+](=O)[O-].N#CCBr>>Cc1nn(CC#N)cc1[N+](=O)[O-],,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20020115674A1,CC(C)(C)On1c(=O)c2cc(F)c(N3CCCC3)c(F)c2n(C2CC2)c1=O>>O=c1c2cc(F)c(N3CCCC3)c(F)c2n(C2CC2)c(=O)n1O,,O=C(O)C(F)(F)F,,,,test
US05888941,CCOC(=O)C(C=O)C=O.NNc1ccc(Cl)cc1>>CCOC(=O)c1cnn(-c2ccc(Cl)cc2)c1,,CCO,,Cl,,test
US05811389,CCO.CCOC(OCC)OCC.COc1ccc2c(c1)Oc1c(ccc(OC)c1C=O)C2(C)C>>COc1ccc2c(c1)Oc1c(ccc(OC)c1C(OC)OC)C2(C)C,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20090124649A1,Brc1ccc2cn[nH]c2c1.CI>>Cn1ncc2ccc(Br)cc21,,CCOCC,CO,[K+].[OH-],,test
US20080200697A1,COc1ccc(C23OC2CCc2ccccc23)cc1>>COc1ccc(C2C(=O)CCc3ccccc32)cc1,,Cc1ccccc1,,O=S(=O)([O-])[O-].[Mg+2],,test
US06881749B2,C[C@@H](Cn1ncc2ccc(O)cc21)O[Si](C)(C)C(C)(C)C.O=C1CCC(=O)N1Br>>C[C@@H](Cn1ncc2ccc(O)c(Br)c21)O[Si](C)(C)C(C)(C)C,,C1CCOC1,,O=S([O-])O.[Na+],,test
US20050261245A1,CC(C)(C)[Si](C)(C)OCc1cccc(O)c1.CS(=O)(=O)c1ccc(/C(CO)=C(/CO)c2ccccc2)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)(C)[Si](C)(C)OCc1cccc(OC(=O)OC/C(=C(\CO)c2ccccc2)c2ccc(S(C)(=O)=O)cc2)c1,,ClCCl,,c1ccncc1,,test
US20040072827A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)CNCCCn1c(-c2ccc(F)cc2)csc1=Nc1ccc(Cl)cc1OC>>CCOC(=O)CN(CCCn1c(-c2ccc(F)cc2)csc1=Nc1ccc(Cl)cc1OC)C(=O)OC(C)(C)C,,C1CCOC1,,,,test
US20120071461A1,CN(C(=O)c1ccc2c(c1)[C@H](NC(=O)c1ccccc1Cl)CC2)C1CCNCC1.NCc1nccc(Cl)n1>>CNc1nccc(N2CCC(N(C)C(=O)c3ccc4c(c3)[C@H](NC(=O)c3ccccc3Cl)CC4)CC2)n1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20050256140A1,COc1ncnc2sc(-c3c(-c4ccccc4)nc(-c4ccsc4)n3C)nc12.N>>Cn1c(-c2ccsc2)nc(-c2ccccc2)c1-c1nc2c(N)ncnc2s1,,C1COCCO1,,,,test
US20080227782A1,COC(=O)c1cnc(C#N)nc1.NO>>COC(=O)c1cnc(C(=N)NO)nc1,,CO,,Cl,CC(=O)[O-].[Na+],test
US20060111375A1,CC(=O)Cl.CSc1ccc(O)cc1C>>CSc1ccc(OC(C)=O)cc1C,,ClCCl,,c1ccncc1,,test
US20080207654A1,CCCCc1nc(C)n(CC(C)(C)CO[Si](C)(C)C(C)(C)C)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nc(C)n(CC(C)(C)CO)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US06750219B1,C=C(C)C.COCCOC.NC[C@H](O)C(=O)O>>CC(C)(C)OC(=O)[C@H](CN)OC(C)(C)C,,COCCOC,,O=S(=O)(O)O,,test
US20090298823A1,C[S-].Clc1nc(Cl)c2cc[nH]c2n1>>CSc1nc(Cl)nc2[nH]ccc12,,CS(C)=O,,O,,test
US20150126490A1,CC1(c2ccc(N)nc2)CCOCC1.O=C1CCC(=O)N1Br>>CC1(c2cnc(N)c(Br)c2)CCOCC1,,CCOC(C)=O,ClCCl,,,test
US20080105851A1,Cc1nc2ccccc2[nH]1.ClCc1ccccc1>>Cc1nc2ccccc2n1Cc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040204386A1,Nc1ccc(Br)cc1.Nc1nc(Cl)cc(-c2cc(Cl)ccc2Cl)n1>>Nc1nc(Nc2ccc(Br)cc2)cc(-c2cc(Cl)ccc2Cl)n1,,CCO,,CCOC(C)=O,,test
US20080113946A1,CS(=O)(=O)c1nc2c(c(Sc3ccc(NC(=O)C4CC4)cc3)n1)COC2.Cc1cc(N)[nH]n1>>Cc1cc(Nc2nc3c(c(Sc4ccc(NC(=O)C5CC5)cc4)n2)COC3)[nH]n1,,CC(C)O,,Cl,,test
US20100105667A1,CN(C)CCCl.Nc1ccc(O)cc1>>CN(C)CCOc1ccc(N)cc1,,CN(C)C=O,,Cl,[Na+].[OH-],test
US20090220381A1,CC(C)(C)OC(=O)c1cc(O)cc(C(=O)OC(C)(C)C)c1.O=C(CCCCCCCCCCBr)OCc1ccccc1[N+](=O)[O-]>>CC(C)(C)OC(=O)c1cc(OCCCCCCCCCCC(=O)OCc2ccccc2[N+](=O)[O-])cc(C(=O)OC(C)(C)C)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05686460,CNC.CS(=O)(=O)c1ccc(C(=C2CCCC2)c2ccc(Cl)nc2)cc1>>CN(C)c1ccc(C(=C2CCCC2)c2ccc(S(C)(=O)=O)cc2)cn1,,CCO,,,,test
US06090805,BrCC1CO1.COC(=O)Cc1ccc(O)cc1OCC(F)(F)F>>COC(=O)Cc1ccc(OCC2CO2)cc1OCC(F)(F)F,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US04867964,CC(=O)c1ccc(O)cc1O.COc1ccc(C=O)cc1>>COc1ccc(C(=O)C=Cc2ccc(O)cc2O)cc1,,CCO,,Cl,[K+].[OH-],test
US04808595,Cc1cc2oc(S(=O)(=O)N=CN(C)C)cc2cn1.O=C(OO)c1cccc(Cl)c1>>Cc1cc2oc(S(=O)(=O)N=CN(C)C)cc2c[n+]1[O-],,ClC(Cl)Cl,,,,test
US06350749B1,Cc1cc(F)ccc1Cl.O=[Cr](=O)(O)O>>O=Cc1cc(F)ccc1Cl,,CC(=O)OC(C)=O,,O=S(=O)(O)O,,test
US04935049,Cc1nc(C(O)(CBr)c2ccc(F)cc2)cs1.c1nc[nH]n1>>Cc1nc(C(O)(Cn2cncn2)c2ccc(F)cc2)cs1,,CN(C)C=O,,[H-].[Na+],,test
US20060178381A1,C=Cc1cc2c(cc1C(F)(F)F)CN(C(=O)OC(C)(C)C)C2>>CCc1cc2c(cc1C(F)(F)F)CN(C(=O)OC(C)(C)C)C2,[Pd],CO,,,,test
US06653334B1,CC(C)(C)OC(=O)C(C)(C)Oc1cccc(CCCO)c1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)C(C)(C)Oc1cccc(CCCOS(C)(=O)=O)c1,,ClCCl,,CCN(CC)CC,Cl,test
US20150259350A1,Cl.Cn1cc(-c2cnc3nnn(C[C@@H]4CN(c5ncc(-c6cnn(C7CCN(C(=O)OC(C)(C)C)CC7)c6)cn5)CCO4)c3n2)cn1>>Cl.Cn1cc(-c2cnc3nnn(C[C@@H]4CN(c5ncc(-c6cnn(C7CCNCC7)c6)cn5)CCO4)c3n2)cn1,,C1COCCO1,ClCCl,,,test
US05130119,Nc1ccc(F)cc1C(F)(F)F.O=S(=O)(Cl)c1cccc(S(=O)(=O)Cl)c1>>O=S(=O)(Cl)c1cccc(S(=O)(=O)Nc2ccc(F)cc2C(F)(F)F)c1,,CC(Cl)Cl,,Cl,c1ccncc1,test
US04348527,O=C(Cl)c1ccc(Cl)cc1.O=C(NC1=NN(c2ccc(Cl)c(Cl)c2)CC1)C(F)(F)F>>O=C(NC1=NN(c2ccc(Cl)c(Cl)c2)CC1)c1ccc(Cl)cc1,,O,,c1ccncc1,,test
US06262045B1,CCOC(=O)c1cc2cc(F)ccc2n1CC.CO.O=C(Cl)C(=O)Cl>>CCOC(=O)c1c(C(=O)C(=O)OC)c2cc(F)ccc2n1CC,,Cc1ccccc1,,CC(C)O,,test
US20110230459A1,CC1(C)NCCNC1=O.O=C(O)CN1CCCC(c2ccccc2)(c2ccccc2)C1=O>>CC1(C)C(=O)NCCN1C(=O)CN1CCCC(c2ccccc2)(c2ccccc2)C1=O,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030232832A1,CCC(NC1CCCCC1)c1nn2cccc2c(=O)n1Cc1ccccc1.O=C(Cl)c1ccccc1>>CCC(c1nn2cccc2c(=O)n1Cc1ccccc1)N(C(=O)c1ccccc1)C1CCCCC1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20050234042A1,CC(C)(C)OC(=O)N[C@H](C(=O)N1CCC[C@H]1c1cccc(Oc2ccccc2)c1)C1CCCCC1.O=C(O)C(F)(F)F>>N[C@H](C(=O)N1CCC[C@H]1c1cccc(Oc2ccccc2)c1)C1CCCCC1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US04271152,CC(C)(C)OC(=O)[C@@H]1CCCN1.C[C@@H](O)[C@H](NC(=O)OCc1ccccc1)C(=O)O>>C[C@@H](O)[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US04395406,C=CCBr.O=c1ncc(F)c[nH]1>>C=CCn1cc(F)cnc1=O,,CO,,[Na],,test
US20140371199A1,CC(C)(C)OC(=O)NC1CCN(C(=O)c2ccc(-c3ccn4ncc(-c5ccc(C#N)cc5)c4n3)cc2)CC1>>N#Cc1ccc(-c2cnn3ccc(-c4ccc(C(=O)N5CCC(N)CC5)cc4)nc23)cc1,,C1COCCO1,ClCCl,Cl,O=C([O-])O.[Na+],test
US20150094297A1,CCOC(=O)c1csc(-c2ccccc2)n1>>O=C(O)c1csc(-c2ccccc2)n1,,CO,O,[Na+].[OH-],,test
US20120184543A1,C1C[C@@H]2CC3(C[C@@H]2CN1)OCCO3.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC[C@@H]2CC3(C[C@@H]2C1)OCCO3,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20050165063A1,CCCN(CCC)Cc1ccc(NCc2ccc(CN)cc2)cc1.O=Cc1ncc[nH]1>>CCCN(CCC)Cc1ccc(NCc2ccc(CNCc3ncc[nH]3)cc2)cc1,,CO,,,,test
US07371773B2,COc1ccc(/C(C#N)=C/c2ccc([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc2)cc1OC.O=P([O-])(Cl)OCC(Cl)(Cl)Cl>>COc1ccc(/C(C#N)=C/c2ccc([C@@H]3O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O)[C@H]3O)cc2)cc1OC,,c1ccncc1,,,,test
US20090221555A1,C#CCCl.O=[N+]([O-])c1ccc2c(c1)C1CNCC2O1>>C#CCN1CC2OC(C1)c1cc([N+](=O)[O-])ccc12,,O=C([O-])O,[Na+],C1CCOC1,O=C([O-])[O-].[K+].[K+],test
US08742113B2,CCOC(=O)C1=C(NCc2ccc(F)cc2)OC(=Cc2c[nH]c3ncccc23)C1=O>>O=C1C=C(NCc2ccc(F)cc2)OC1=Cc1c[nH]c2ncccc12,,CC(=O)N(C)C,O,,,test
US20100168103A1,CN1CCN(C(=O)C2(c3ccccc3)CCN(Cc3ccccc3)CC2)CC1>>CN1CCN(C(=O)C2(c3ccccc3)CCNCC2)CC1,[Pd],CO,,[H][H],,test
US05750531,CCc1cc(N2CCc3ccccc3C2C)nc(Cl)n1.CNc1ccccc1>>CCc1cc(N2CCc3ccccc3C2C)nc(N(C)c2ccccc2)n1.Cl,,CN(C)C=O,,,,test
US20100197679A1,CCOC(=O)CNc1ncc(OC)cc1Nc1cnc2c(c1)CCC(NC(=O)OC(C)(C)C)C2>>COc1cnc2c(c1)N(c1cnc3c(c1)CCC(NC(=O)OC(C)(C)C)C3)C(=O)CN2,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US05162326,CCCCCS.CCCn1c(=O)cc(Cl)n(Cc2ccc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)c1=O>>CCCCCSc1cc(=O)n(CCC)c(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120065210A1,CC(C)(C)CC1N(CCO[Si](C)(C)C(C)(C)C)C(C(=O)OC(C)(C)C)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.O=C(O)C(F)(F)F>>CC(C)(C)CC1N(CCO[Si](C)(C)C(C)(C)C)C(C(=O)O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20070149608A1,CC(C)Br.COC(=O)c1ccc(O)c(Br)c1>>COC(=O)c1ccc(OC(C)C)c(Br)c1,,CN(C)C=O,,[I-].[K+],,test
US06242443B1,CC(C)N=C=S.Nc1c(Br)cc(Br)cc1S(N)(=O)=O>>CC(C)NC1=NS(=O)(=O)c2cc(Br)cc(Br)c2N1,,CCOC(C)=O,,,,test
US20070219181A1,CC(C)(C)OC(=O)NNC(=O)C(CCCCl)c1c(F)cc(F)cc1F.Cl>>Cl.NNC(=O)C(CCCCl)c1c(F)cc(F)cc1F,,CC(=O)O,CCOC(C)=O,,,test
US06329405B1,COc1ccc(C(NCCC(c2ccccc2)c2ccccc2)c2cccc(Nc3c(OC)c(=O)c3=O)c2)cc1.N>>COc1ccc(C(NCCC(c2ccccc2)c2ccccc2)c2cccc(Nc3c(N)c(=O)c3=O)c2)cc1,,CCO,,,,test
US20040002506A1,C1CCOC1.CCOC(=O)CCCCCC(C(=O)O)C(=O)O.CN(C)c1ccncc1.ClCCCl.Nc1cccc2cccnc12>>CCOC(=O)CCCCCC(C(=O)Nc1cccc2cccnc12)C(=O)Nc1cccc2cccnc12,CN(C)c1ccncc1,C1CCOC1,,,,test
US20080176833A1,COC(=O)c1ccc2[nH]ncc2n1>>OCc1ccc2[nH]ncc2n1,,C1CCOC1,CCOCC,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US04013662,COC(=O)Cl.COc1cc2c(cc1OC)C(=O)CC(C)N2>>COC(=O)N1c2cc(OC)c(OC)cc2C(=O)CC1C,,ClCCl,,c1ccncc1,,test
US20130184222A1,Cc1ccccc1C(Nc1cccc(F)c1)C(=O)NC1CCC(F)(F)CC1.O=C(Cl)CCl>>Cc1ccccc1C(C(=O)NC1CCC(F)(F)CC1)N(C(=O)CCl)c1cccc(F)c1,,Cc1ccccc1,,CCOC(C)=O,,test
US20040147511A1,O=C(O)c1ccc(-c2cccnc2)cc1.O=C(OO)c1cccc(Cl)c1>>O=C(O)c1ccc(-c2ccc[n+]([O-])c2)cc1,,C1CCOC1,,,,test
US03954757,II.O=C(O)c1cc2ccccc2[nH]1.SC1=NCCCN1>>I.O=C(O)c1[nH]c2ccccc2c1SC1=NCCCN1,,CO,O,[I-].[K+],,test
US20110306591A1,COCn1cnc2ccccc21.CON(C)C(=O)C1CC(Oc2ncc(F)cc2C2CCOCC2)C1>>COCn1c(C(=O)C2CC(Oc3ncc(F)cc3C3CCOCC3)C2)nc2ccccc21,,C1CCOC1,,[Li]CCCC,,test
US04199586,CCCn1cc(-c2ccncc2)cc([N+](=O)[O-])c1=O>>CCCn1cc(-c2ccncc2)cc(N)c1=O,[Ni],CN(C)C=O,,[H][H],,test
US20120065196A1,CNC.COC(=O)[C@@H]1CC[C@@H](c2nnc(CCl)o2)CC1>>COC(=O)[C@@H]1CC[C@@H](c2nnc(CN(C)C)o2)CC1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20110105530A1,BrCc1ccccc1.O=C(NCc1ccccc1)c1ccnc(N2CCCCC2=O)c1>>O=C(NCc1ccccc1)c1ccnc(N2CCCC(Cc3ccccc3)C2=O)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20140005178A1,CCOC(=O)c1cc(C)ccc1Nc1cnc2ccccc2c1>>Cc1ccc(Nc2cnc3c(c2)CCCC3)c(C(=O)O)c1,O=[Pt]=O,O=C(O)C(F)(F)F,,,,test
US20140296208A1,COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)cc(NS(C)(=O)=O)c4OC)c4ccccc34)n2)cc(OC)c1>>COCCOCCOCCOc1cc(N)cc(OC)c1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20120225854A1,O=[N+]([O-])c1ccccc1S(=O)(=O)N1CCN(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)CC1>>Nc1ccccc1S(=O)(=O)N1CCN(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)CC1,[Pd],CCO,,,,test
US04826818,CCCCCCCCCCCCCCO.C[C@H](N)C(=O)O.Cc1ccc(S(=O)(=O)O)cc1>>CCCCCCCCCCCCCCOC(=O)[C@H](C)N.Cc1ccc(S(=O)(=O)O)cc1,,O,c1ccccc1,,,test
US20100081692A1,COC(=O)/C=C/c1ccc(F)cc1O>>COC(=O)CCc1ccc(F)cc1O,[Pt],CCOC(C)=O,,,,test
US06075018,COc1cccc(C=CC2=NN=C(C)Cc3cc4c(cc32)OCO4)c1OC.Cl>>COc1cccc(C=CC2=NNC(C)Cc3cc4c(cc32)OCO4)c1OC.Cl,,CCOC(C)=O,,,,test
US20070129408A1,CNC(=S)NNC(=O)c1ccncc1>>Cn1c(-c2ccncc2)n[nH]c1=S,,O,,Cl,O=C([O-])O.[Na+],test
US20050261327A1,O=[N+]([O-])C=C1CCC2(CC1)OCCc1ccccc12>>NCC1CCC2(CC1)OCCc1ccccc12,[Ni],CO,O,,,test
US20100204272A1,CC1(c2ccc(O)c(N)c2)OCCO1.CON>>CON=C(C)c1ccc(O)c(N)c1,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US03961055,CCCCCCC(=O)Cl.COc1ccc2c(c1)N(CCCN1CCC(CCO)CC1)c1cccc(S(=O)(=O)N(C)C)c1S2>>CCCCCCC(=O)OCCC1CCN(CCCN2c3cc(OC)ccc3Sc3c2cccc3S(=O)(=O)N(C)C)CC1,,Cc1ccccc1,O,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US20100249085A1,CC(C)(C)OC(=O)N1CCC(O)CC1.N#Cc1ccc(CBr)cc1>>CC(C)(C)OC(=O)N1CCC(OCc2ccc(C#N)cc2)CC1,,C1CCOC1,,CCOC(C)=O,[H-].[Na+],test
US20100029737A1,CCOC(=O)c1cc2c([nH]1)[C@@H]1C[C@@H]1C2>>O=C(O)c1cc2c([nH]1)[C@@H]1C[C@@H]1C2,,C1CCOC1,,CO,[Li+].[OH-],test
US20040110786A1,CC(C)(C)OC(=O)N1CCCC1.O=Cc1ccccc1>>CC(C)(C)OC(=O)N1CCCC1C(O)c1ccccc1,,CCOCC,,[Li]C(C)CC,,test
US20140336378A1,CCCCOc1c(C)cc(C(=O)OC)cc1C>>CCCCOc1c(C)cc(C(=O)O)cc1C,,[K+],[OH-],CO,,test
US20100160309A1,CC(C)(C)OC(=O)C(C)(C)c1nc2ccnc(Cl)c2c2cc(Br)ccc12.O=C(O)C(F)(F)F>>CC(C)c1nc2cc[nH]c(=O)c2c2cc(Br)ccc12,,ClCCl,,,,test
US20040259923A1,CC(=O)Nc1nc(CCc2ccc(CBr)cc2)cs1.CN(C)C=O.O>>CC(=O)Nc1nc(CCc2ccc(CN(C=O)C=O)cc2)cs1,,O,,C1CCOC1,,test
US20140275083A1,CC(C)(C)[S@@](=O)/N=C/c1ccn(-c2ccc(Cl)cc2)n1.C[Mg]Br>>C[C@@H](N[S@](=O)C(C)(C)C)c1ccn(-c2ccc(Cl)cc2)n1,,ClCCl,,,,test
US20100222321A1,Cn1cnc(-c2nnc3c4cc(-c5ccccc5)c(-c5ccc(C6OCCO6)cc5)nc4ccn23)c1>>Cn1cnc(-c2nnc3c4cc(-c5ccccc5)c(-c5ccc(C=O)cc5)nc4ccn23)c1,,C1CCOC1,,Cl,,test
US20110207736A1,C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(C)CC4)cc3OC)nc3c2cnn3C2CCCCO2)c1.COc1cc(N2CCN(C)CC2)ccc1Nc1nnc(C(=O)N(C)OC)s1>>COc1cc(N2CCN(C)CC2)ccc1Nc1nnc(C(=O)c2cccc(N)c2)s1,,C1CCOC1,,,,test
US20020002190A1,Nc1nccs1.O=C(O)C(CC1CCCC1)c1ccc(-c2ccccc2)cc1>>O=C(Nc1nccs1)C(CC1CCCC1)c1ccc(-c2ccccc2)cc1,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20030216373A1,CC(=O)OCC(=O)Cl.O=C1O[C@@H](Cn2ccnn2)CN1c1cc(F)c(C2=CCNCC2)c(F)c1>>CC(=O)OCC(=O)N1CC=C(c2c(F)cc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)CC1,,CC(C)=O,O,Cl,O=C([O-])O.[Na+],test
US20100113462A1,CC(C)Br.CCOC(=O)C1(NC(=O)c2cccc(C)c2O)Cc2ccccc2C1>>CCOC(=O)C1(NC(=O)c2cccc(C)c2OC(C)C)Cc2ccccc2C1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04396627,CC(=O)Cl.CC(O)Cc1ccccc1>>CC(=O)OC(C)Cc1ccccc1,,CCOCC,,,,test
US20150307494A1,COc1ccc(Cn2c(=O)c(C)c(-c3ccc(O)cc3C)n(C)c2=O)cc1OC.Clc1nccc2ccccc12>>COc1ccc(Cn2c(=O)c(C)c(-c3ccc(Oc4nccc5ccccc45)cc3C)n(C)c2=O)cc1OC,,CS(C)=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20070124152A1,CCOCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCN2C(=O)c3ccccc3C2=O)c1=O>>CCOCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCCN)c1=O,,CCO,,NN,O,test
US04587238,COC(=O)C(C)N1CCCCCCC(N=[N+]=[N-])C1=O>>CC(C(=O)O)N1CCCCCCC(N=[N+]=[N-])C1=O,,[Na+],[OH-],,,test
US06610502B1,CCOC(=O)C(Cc1c([C@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)[nH]c2ccccc12)=NO>>CCOC(=O)C(N)Cc1c([C@H]2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)[nH]c2ccccc12,,C1CCOC1,O,[Al],,test
US20080064715A1,Cl[Mg]c1ccccc1.O=Cc1c[nH]c2cnccc12>>OC(c1ccccc1)c1c[nH]c2cnccc12,,C1CCOC1,,,,test
US20040092556A1,COC(=O)c1ccc(CCN(Cc2ccccn2)C(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)N(CCc1ccc(C(=O)O)cc1)Cc1ccccn1,,C1CCOC1,,CO,[Na+].[OH-],test
US04423047,OC(CCl)CSc1ncc(Cl)cn1.OO>>O=S(CC(O)CCl)c1ncc(Cl)cn1,,CO,O,[Cl-].[Na+],,test
US20040026230A1,C#CCO.C1=COCC1.O=C1CCC(=O)N1Br>>C#CCOC1OCCC1Br,,ClCCl,,,,test
US07709479B1,COc1cc([N+](=O)[O-])ccc1N.O=C(Cl)c1ccccc1>>COc1cc([N+](=O)[O-])ccc1NC(=O)c1ccccc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20070149533A1,CC(C)(C)[Si](C)(C)Cl.O=[N+]([O-])c1cc(CO)cc(C(F)(F)F)c1>>CC(C)(C)[Si](C)(C)OCc1cc([N+](=O)[O-])cc(C(F)(F)F)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040106645A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.O=c1cc(O)c2cc(OC(F)F)ccc2o1>>O=c1cc(OS(=O)(=O)C(F)(F)F)c2cc(OC(F)F)ccc2o1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110034507A1,COC(=O)c1cccc(-c2ccc3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3c2)c1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2ccc(-c3cccc(C(=O)O)c3)cc2c1,,C1CCOC1,,CO,[Na+].[OH-],test
US20060008730A1,CCOC(=O)C1C2C=CC(C2)C1C(F)(F)F>>O=C(O)C1C2C=CC(C2)C1C(F)(F)F,,O,,Cl,[Na+].[OH-],test
US20060217382A1,COc1cc(Nc2ncc(C(C)NC(=O)c3ccccc3NC(=O)C(F)(F)F)nn2)cc(OC)c1OC>>COc1cc(Nc2ncc3c(C)nc(-c4ccccc4NC(=O)C(F)(F)F)n3n2)cc(OC)c1OC,,ClCCCl,,O=P(Cl)(Cl)Cl,,test
US20140179695A1,COc1cnc(C(=O)Nc2ccc3c(c2)[C@@]2(COC(NC(=O)OC(C)(C)C)=N2)C2(CC2)C(C)(C)O3)cn1>>COc1cnc(C(=O)Nc2ccc3c(c2)[C@@]2(COC(N)=N2)C2(CC2)C(C)(C)O3)cn1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20110009399A1,COCCCOc1ccc([C@@]2(O)CCN(C(=O)OC(C)(C)C)C[C@@H]2OCc2ccc3c(c2)N(CCCOC)CCO3)c(CCO)c1.Cc1ccc(S(=O)(=O)Cl)cc1>>COCCCOc1ccc([C@@]2(O)CCN(C(=O)OC(C)(C)C)C[C@@H]2OCc2ccc3c(c2)N(CCCOC)CCO3)c(CCOS(=O)(=O)c2ccc(C)cc2)c1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20070015747A1,CCOC(=O)N1CCC(Nc2nc3ccccc3[nH]2)CC1.O=C(CBr)c1ccc(Cl)cc1>>CCOC(=O)N1CCC(Nc2nc3ccccc3n2CC(=O)c2ccc(Cl)cc2)CC1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US04230707,O=C(O)c1ccc2nc3c(c(=O)n2c1)SCC3.O=C(n1ccnc1)n1ccnc1>>NC(=O)c1ccc2nc3c(c(=O)n2c1)SCC3,,C1CCOC1,CN(C)C=O,O=C([O-])O.[Na+],,test
US20070259898A1,COC(=O)C=CC(NC(=O)OC(C)(C)C)C1CCCCC1>>COC(=O)CCC(NC(=O)OC(C)(C)C)C1CCCCC1,[Pd],CO,,,,test
US20060122064A1,C=CCOc1ccc(CCC(=O)OCC)cc1OC>>C=CCOc1ccc(CCC(=O)O)cc1OC,,CCO,,[Na+].[OH-],,test
US20080234305A1,COC(=O)C1=C(c2ccc(CCCO)cc2)C2(CC2)CN(C(=O)OC(C)(C)C)C1.Oc1c(F)ccc(F)c1Cl>>COC(=O)C1=C(c2ccc(CCCOc3c(F)ccc(F)c3Cl)cc2)C2(CC2)CN(C(=O)OC(C)(C)C)C1,,CCOC(C)=O,Cc1ccccc1,CCCCP(CCCC)CCCC,,test
US20100069361A1,O=C1COc2ccc(Cl)cc2N1>>Clc1ccc2c(c1)NCCO2,,C1CCOC1,,B,,test
US04603201,C[S-].Cc1c(Cl)cc(C(=O)C=CC(=O)O)cc1Cl>>CSC(CC(=O)c1cc(Cl)c(C)c(Cl)c1)C(=O)O,,O,,Cl,,test
US04536504,CC(=O)OC1NC(=O)NC(=O)C1(F)C(=O)OCC(C)C.O/N=C/c1ccco1>>CC(C)COC(=O)C1(F)C(=O)NC(=O)NC1O/N=C/c1ccco1,,c1ccncc1,,CCN(CC)CC,,test
US05427793,C=C(C)C(=O)OCCC[Si](OC)(OC)OC.C=CC(=O)[O-].[Sn]>>C=C(C)C(=O)OCCC[Si](OC)(OC)OC.C=CC(=O)[O-].[Sn],,c1ccccc1,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US05397793,Brc1cncnc1.N#CC(CCc1ccc(Cl)cc1)c1ccccc1F>>N#CC(CCc1ccc(Cl)cc1)(c1cncnc1)c1ccccc1F,,CN(C)C=O,,[H-].[Na+],,test
US20150274704A1,CC(C)(C)OC(=O)N1CCC2(CCC(=O)CC2)CC1.CN>>CNC1CCC2(CC1)CCN(C(=O)OC(C)(C)C)CC2,,CCO,,[BH3-]C#N.[Na+],,test
US20140371195A1,CNCCCc1nccn1C.O=C(N[C@H](CO)C(=O)O)OCc1ccccc1>>CN(CCCc1nccn1C)C(=O)[C@@H](CO)NC(=O)OCc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120329780A1,COC(=O)c1cccc(-c2nc(Cl)c3nn(Cc4ccc(OC)cc4)cc3n2)c1.Nc1ccc(N2CCOCC2)cc1>>COC(=O)c1cccc(-c2nc(Nc3ccc(N4CCOCC4)cc3)c3[nH]ncc3n2)c1,C1COCCO1,CO,,Cl,,test
US09266853B2,CC#CCOc1ccc(C[C@H](NC(=O)[C@@H](/C=C/CCCCCCC(=O)CCCCCCC)[C@@](O)(CCO)C(=O)OC(C)(C)C)C(=O)OC)cc1.CC(=O)OC(C)=O>>CC#CCOc1ccc(C[C@H](NC(=O)[C@@H](/C=C/CCCCCCC(=O)CCCCCCC)[C@@](O)(CCOC(C)=O)C(=O)OC(C)(C)C)C(=O)OC)cc1,,ClCCl,,CCN(CC)CC,CN(C)c1ccccn1,test
US20080161314A1,C#Cc1ccccc1.CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2c1ccc(Br)nn1.CCN(C(C)C)C(C)C>>CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2c1ccc(C#Cc2ccccc2)nn1.N,[Cu]I,C1COCCO1,,[Na+].[OH-],,test
US20060229330A1,COc1cc(F)ccc1C(=O)c1cnc(NC2CCN(C(=O)OC(C)(C)C)CC2)nc1N>>COc1cc(F)ccc1C(=O)c1cnc(NC2CCNCC2)nc1N,,ClCCl,O=C(O)C(F)(F)F,,,test
US06666989B1,CC[C@@H](C)COC(=O)c1ccc(OC(=O)OC)cc1>>CC[C@@H](C)COC(=O)c1ccc(O)cc1,,CCO,,N,,test
US05250522,COP(=O)(CN[C@@H](Cc1ccc(-c2ccccc2)cc1)C(=O)O)OC>>O=C(O)[C@H](Cc1ccc(-c2ccccc2)cc1)NCP(=O)(O)O,,Br,CC(=O)O,CCOCC,,test
US20100204196A1,CNC.CNc1ccc(OC)cc1C.O=C(Cl)CBr>>COc1ccc(N(C)C(=O)CN(C)C)c(C)c1,,C1CCOC1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US05057525,O=C(N[C@@H]1CCN(Cc2ccccc2)C[C@H]1OCc1ccccc1)c1ccccc1>>O=C(N[C@@H]1CCNC[C@H]1O)c1ccccc1,[Pd],CO,,[H][H],,test
US20090118263A1,COC(=O)Cc1cccc(OCCN(C)CCN(C)C(=O)OC(C)(C)C)c1>>CNCCN(C)CCOc1cccc(CC(=O)OC)c1,,CO,,C1COCCO1,Cl,test
US20070037877A1,Cc1cc(=O)oc2cc(C#N)ccc12.O=C=Nc1cccc(Cl)c1>>N#Cc1ccc2c(CC(=O)Nc3cccc(Cl)c3)cc(=O)oc2c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20040167155A1,COc1cccc(S(=O)(=O)NC(C)c2ccccc2-c2cc(F)ccc2F)c1>>COc1cccc(S(=O)(=O)N2c3ccc(F)cc3-c3ccccc3C2C)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130210824A1,COC(=O)C(=O)C(C)(C)C(=O)OC.NNC(N)=O>>COC(=O)C(=NNC(N)=O)C(C)(C)C(=O)OC,,O,,Cl,CC(=O)[O-].[Na+],test
US20030064991A1,Cc1[nH]c2ccc(CCN3CCCC3)cc2c1C(=O)OCc1ccccc1.Cl>>Cc1[nH]c2ccc(CCN3CCCC3)cc2c1C(=O)OCc1ccccc1.Cl,,CCOCC,ClCCl,,,test
US20130012499A1,CCC(=O)c1cccc(C(F)(F)F)c1.CSc1ccc2c(c1)C(=O)C(=O)N2>>CSc1ccc2nc(-c3cccc(C(F)(F)F)c3)c(C)c(C(=O)O)c2c1,,CCO,O,[K+].[OH-],,test
US20160024077A1,C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OC)c(C)cn3nc(C(=O)OC)cc23)CC1>>C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OC)c(C)cn3nc(C(=O)O)cc23)CC1,,CO,,O,[Na+].[OH-],test
US20040225111A1,CC(C)(C)OC(=O)[C@@H](N)Cc1ccc(O)cc1.Fc1nc2ccccc2s1>>CC(C)(C)OC(=O)[C@H](Cc1ccc(O)cc1)Nc1nc2ccccc2s1,,c1ccncc1,,,,test
US20110065706A1,CC(C)c1nc(N2CCN[C@H](C)C2)no1.N#Cc1cnccc1COc1cnc(Cl)nc1>>CC(C)c1nc(N2CCN(c3ncc(OCc4ccncc4C#N)cn3)[C@H](C)C2)no1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20090215780A1,CCCCC(=O)Nc1ccc(-c2ccc(C(=O)CC(CCc3ccccc3)C(=O)OCC)cc2)cc1.CS(N)(=O)=O>>CCCCC(=O)Nc1ccc(-c2ccc(C(=O)CC(CCc3ccccc3)C(=O)NS(C)(=O)=O)cc2)cc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20030018021A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C(CN1CCC(Cc2ccc(F)cc2)CC1)NCC(=O)c1ccc2[nH]c(=O)sc2c1>>O=c1[nH]c2ccc(-c3cnc(CN4CCC(Cc5ccc(F)cc5)CC4)s3)cc2s1,,C1COCCO1,CCOC(C)=O,,,test
US20150011527A1,CCCCCCCOc1ccc(-c2nc(-c3ccc(C[C@H](NC(=O)c4ccc(C(C)(C)C)cc4)C(=O)OC)cc3)no2)cc1>>CCCCCCCOc1ccc(-c2nc(-c3ccc(C[C@H](NC(=O)c4ccc(C(C)(C)C)cc4)C(=O)O)cc3)no2)cc1,,CO,,[Na+].[OH-],,test
US20160152605A1,COc1ccncc1.N#Cc1ccc(Br)cc1.O=C(Cl)OCc1ccccc1>>N#Cc1ccc(C2CC(=O)C=CN2C(=O)OCc2ccccc2)cc1,,C1CCOC1,,,,test
US20080242685A1,Nc1c(Cl)cc(Br)nc1Cl.OB(O)c1ccccc1>>Nc1c(Cl)cc(-c2ccccc2)nc1Cl,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070244095A1,CCc1cc2c(cc1C(F)(F)F)N(C(=O)OC(C)(C)C)CCC[C@H]2O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CCc1cc2c(cc1C(F)(F)F)N(C(=O)OC(C)(C)C)CCC[C@@H]2N=[N+]=[N-],,Cc1ccccc1,,C1CCC2=NCCCN2CC1,,test
US20090093476A1,COC(=O)c1cc(-c2ccccc2)c[nH]1.O=[N+]([O-])c1cc(N2CCOCC2)ccc1F>>COC(=O)c1cc(-c2ccccc2)cn1-c1ccc(N2CCOCC2)cc1[N+](=O)[O-],,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US07582794B2,Cc1cccc2c1C(=O)OC2.Oc1cccc(O)c1>>Cc1cccc(COc2cccc(O)c2)c1C(=O)O,,CN1CCCC1=O,O,Cl,CC(C)(C)[O-].[K+],test
US04279910,COc1cc2nc(N3CCNCC3)nc(N)c2cc1OC.O=C(Cl)C1CCc2ccccc2O1>>COc1cc2nc(N3CCN(C(=O)C4CCc5ccccc5O4)CC3)nc(N)c2cc1OC,,ClCCl,,,,test
US20040048915A1,CCOC(CBr)OCC.CCc1cccc(N)c1>>CCOC(CNc1cccc(CC)c1)OCC,,CCO,,O=C([O-])O.[Na+],,test
US20160108047A1,CS(=O)(=O)OS(C)(=O)=O.Cc1cc(N2C(=O)c3nc(C4=CCNCC4)n(C(C)C)c3C2c2ccc(Cl)cc2)cn2c(C)nnc12>>Cc1cc(N2C(=O)c3nc(C4=CCN(S(C)(=O)=O)CC4)n(C(C)C)c3C2c2ccc(Cl)cc2)cn2c(C)nnc12,,ClCCl,c1ccncc1,O=C([O-])O.[Na+],,test
US20070219234A1,C/C(=C(\C#N)C(N)=S)N1CCCN(c2ccccn2)CC1.COC(OC)N(C)C>>N#Cc1c(N2CCCN(c3ccccn3)CC2)cc[nH]c1=S,,CN(C)C=O,,,,test
US20050277670A1,CC(C)(C)OC(=O)N1CCC(C(O)c2ccc(C(F)(F)F)cc2)CC1.Clc1cccc(Cl)n1>>CC(C)(C)OC(=O)N1CCC(C(Oc2cccc(Cl)n2)c2ccc(C(F)(F)F)cc2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20090005353A1,O=C1c2ccccc2C(=O)N1CCCCBr.Oc1ccccc1>>O=C1c2ccccc2C(=O)N1CCCCOc1ccccc1,,CC#N,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20040122244A1,COc1c(C)c(Cc2ccc(C(=O)O)c(OCc3ccccc3)c2)c(OC)c(OC)c1OC>>COc1c(C)c(Cc2ccc(C(=O)O)c(O)c2)c(OC)c(OC)c1OC,[Pd],C1COCCO1,,CCO,[H][H],test
US20090176786A1,CI.CN(C(=O)NC(=O)c1c(F)cccc1F)c1ccc(SC(F)(F)F)cc1F>>CN(C(=O)c1c(F)cccc1F)C(=O)N(C)c1ccc(SC(F)(F)F)cc1F,,CN1CCCC1=O,O,[H-].[Na+],[Cl-].[NH4+],test
US20140309452A1,CCOC(C#CCCCCCl)OCC>>O=CC#CCCCCCl,Cc1ccc(S(=O)(=O)O)cc1,C1CCOC1,,O,,test
US20050272791A1,CCCC[Sn](Cl)(CCCC)CCCC.Cc1nc(-c2ccccc2)cs1>>CCCC[Sn](CCCC)(CCCC)c1sc(C)nc1-c1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US20060040999A1,C[C@@H]1NC(=O)O[C@@H]1c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=[N+]([O-])c1ccc(Br)c(CBr)c1>>C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1cc([N+](=O)[O-])ccc1Br,,C1CCOC1,,[H-].[Na+],,test
US04772711,CNC.COC(=O)C(=CO)c1ccccc1>>COC(=O)C(=CN(C)C)c1ccccc1,,O,,Cl,[Na],test
US05143916,COc1ccc2cccc(N3CCNCC3)c2c1.Cl.O=C1NC(=O)c2c(CCBr)cccc21>>COc1ccc2cccc(N3CCN(CCN4C(=O)c5ccccc5C4=O)CC3)c2c1.Cl,,CCOCC,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090192156A1,COC1CCNCC1.COc1cccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)O)c3)c12>>COc1cccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)N4CCC(OC)CC4)c3)c12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05137909,CCCCCCOc1ccc2[nH]c(SC(C)(C(=O)O)c3ccccc3)cc2c1>>CCCCCCOc1ccc2[nH]c(SC(C)(CO)c3ccccc3)cc2c1,,C1CCOC1,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US05859256,CC(C)(C)OC(=O)NCCSSCCNC(=O)OC(C)(C)C.Clc1ccncc1>>CC(C)(C)OC(=O)NCCSc1cnccc1Cl,,C1CCOC1,,Cl,CC(C)[N-]C(C)C.[Li+],test
US20080234260A1,CN1CCN(C(N)=S)CC1.O=C(O)c1cccc(C(=O)CBr)c1>>CN1CCN(c2nc(-c3cccc(C(=O)O)c3)cs2)CC1,,C1CCOC1,,,,test
US20020082250A1,CC(C)COC1C(NC(c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)N1[Si](C)(C)C(C)(C)C>>CC(C)COC1NC(=O)C1NC(c1ccccc1)(c1ccccc1)c1ccccc1,,C1CCOC1,,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20040019016A1,CC(Br)CN(c1ccc(C#N)cc1)n1cnnc1.Oc1ccc(S)cc1>>N#Cc1ccc(N(CCCSc2ccc(O)cc2)n2cnnc2)cc1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20150203493A1,CC1CCC(Oc2cccc3cc(CO)ccc23)CC1.CS(=O)(=O)Cl>>C[C@@H]1CC[C@H](Oc2cccc3cc(COS(C)(=O)=O)ccc23)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120264748A1,Cc1ccc(S(=O)(=O)n2ccc3c(C#N)cccc32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(CN)cccc32)cc1,[Ni],CO,,N,,test
US05952362,CCO.CS(=O)(=O)Nc1cccc(OCC#N)c1.Cl>>CCOC(=N)COc1cccc(NS(C)(=O)=O)c1.Cl,,ClC(Cl)Cl,,,,test
US20060241172A1,BrCc1ccccc1.C=CCc1cccc(-c2c(Cl)cccc2Cl)c1O>>C=CCc1cccc(-c2c(Cl)cccc2Cl)c1OCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20050026968A1,NCc1ccccn1.O=C(Cl)c1ccc([N+](=O)[O-])o1>>O=C(NCc1ccccn1)c1ccc([N+](=O)[O-])o1,,CCN(CC)CC,ClCCl,,,test
US20140200227A1,COc1ccc(F)c(-c2nc(C(=O)O)ccc2F)c1F.C[C@@H]1C[C@H](NC(=O)OC(C)(C)C)CN(c2c(N)cnc3c2CCO3)C1>>COc1ccc(F)c(-c2nc(C(=O)Nc3cnc4c(c3N3C[C@@H](N)C[C@@H](C)C3)CCO4)ccc2F)c1F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04080505,CCOC(=O)C(O)Cc1ccc(OC(C)(C)C(=O)c2ccccc2)cc1.O=S(Cl)Cl>>CCOC(=O)C(Cl)Cc1ccc(OC(C)(C)C(=O)c2ccccc2)cc1,,CCOCC,,c1ccncc1,O=C([O-])O.[Na+],test
US04367238,COc1ccccc1Oc1cccc(C)c1OC.O=C1CCC(=O)N1Br>>COc1ccccc1Oc1cccc(CBr)c1OC,CC(C)(C#N)N=NC(C)(C)C#N,c1ccccc1,,,,test
US20070249580A1,Cc1nc(-c2ccc(Cl)cc2)sc1C=CC1CCCN(C(=O)OCc2ccccc2)C1>>Cc1nc(-c2ccc(Cl)cc2)sc1C=CC1CCCNC1,,Cl,,,,test
US06030977,CCCCCCCC/C=C\CCCCCCCC(=O)O.Cc1cc(C)nc(Nc2ccccc2)n1>>CCCCCCCC/C=C\CCCCCCCC(=O)[O-].Cc1cc(C)nc(Nc2ccccc2)n1,,Cc1ccccc1,,,,test
US20080132549A1,CCc1nc(CO)n(CC)c1Sc1cc(C#N)cc(C#N)c1.O=C1NC(=O)c2ccccc21>>CCc1nc(CN2C(=O)c3ccccc3C2=O)n(CC)c1Sc1cc(C#N)cc(C#N)c1,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160145247A1,COC(=O)Cc1ccccc1OCc1cc(Cl)cc(C#N)c1>>COC(=O)Cc1ccccc1OCc1cc(Cl)cc(CN)c1,,C1CCOC1,,O,[BH4-].[Na+],test
US20090192144A1,COc1ccc(C2(C)COC/C(=C/[N+](=O)[O-])N2)cc1>>COc1ccc(C2(C)COCC(CN)N2)cc1,[Ni],C1CCOC1,CO,,,test
US20060194969A1,CCOC(=O)c1cc(O[C@@H]2c3ccc(Cl)cc3C[C@H]2O)c2nc(C)n(C)c2c1>>Cc1nc2c(O[C@@H]3c4ccc(Cl)cc4C[C@H]3O)cc(C(=O)O)cc2n1C,,C1COCCO1,,Cl,[Na+].[OH-],test
US20080058309A1,CC(C)(C)OC(=O)Nc1c(Cl)ccc2nc(N3CCOCC3)ccc12>>Nc1c(Cl)ccc2nc(N3CCOCC3)ccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US05624935,CCO.O=C(O)C1Cc2ccccc2N1>>CCOC(=O)C1Cc2ccccc2N1,,C1COCCO1,,Cl,O=C([O-])[O-].[K+].[K+],test
US20040106667A1,CNC(=O)c1n[nH]c2ccc(N)cc12.O=S(=O)(Cl)c1cccc(F)c1>>CNC(=O)c1n[nH]c2ccc(NS(=O)(=O)c3cccc(F)c3)cc12,,c1ccncc1,,,,test
US20060122263A1,N[C@H]1CO[C@@H](C(c2ccccc2)c2ccccc2)C[C@@H]1O.O=Cc1ccc(O)cc1>>Oc1ccc(CN[C@H]2CO[C@@H](C(c3ccccc3)c3ccccc3)C[C@@H]2O)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20120114739A1,CCOC(C)=O.COC(=O)C1CCC(C(=O)O)CC1>>CCOC(=O)CC(=O)C1CCC(C(=O)OC)CC1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20080242666A1,CC(=O)Cl.CCC(CC)[C@@H]1C(=O)N[C@H](C2Cc3ccccc3C2)C(=O)N1Cc1ccccc1N>>CCC(CC)[C@@H]1C(=O)N[C@H](C2Cc3ccccc3C2)C(=O)N1Cc1ccccc1NC(C)=O,,ClCCl,,c1ccncc1,,test
US20060205787A1,Br.C[C@@]1(N)CCC(=O)NC1=O.O>>Br.C[C@]1(N)CCC(=O)NC1=O.O,,CCO,,,,test
US20150045368A1,BrP(Br)Br.CCOC(C)=O.Oc1ccnc2cc(F)cnc12>>COc1ccc2nccc(Br)c2n1,,CN(C)C=O,,,,test
US20020016368A1,CCOC(=O)Cc1cccc(CNCc2ccc(C)cc2)c1.CS(=O)(=O)Cl>>CCOC(=O)Cc1cccc(CN(Cc2ccc(C)cc2)S(C)(=O)=O)c1,,ClCCl,,CCN(CC)CC,Cl,test
US05480857,Cn1nc(C(F)(F)F)c(C(=O)O)c1Cl.Fc1ccc(S)cc1>>Cn1nc(C(F)(F)F)c(C(=O)O)c1Sc1ccc(F)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04954518,CS(=O)(=O)Cl.Nc1cc(O)ccc1Oc1ccccc1>>CS(=O)(=O)Nc1cc(O)ccc1Oc1ccccc1,,ClCCl,O,Cl,c1ccncc1,test
US03998879,CCC1CC(=O)CC(=O)C1.Cc1ccc(S(=O)(=O)N=C=O)cc1>>CCC1CC(=O)C(C(=O)NS(=O)(=O)c2ccc(C)cc2)C(=O)C1,,c1ccccc1,,,,test
US07022707B2,CC(=O)SCc1ccc(O[Si](C)(C)C(C)(C)C)cc1>>CC(C)(C)[Si](C)(C)Oc1ccc(CS)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20010016579A1,CN1CCNCC1.Cc1c(Cl)cc2nc(S)oc2c1Cl>>Cc1c(Cl)cc2nc(N3CCN(C)CC3)oc2c1Cl,,ClC(Cl)Cl,,,,test
US20090192138A1,BrCc1nccc2ccccc12.CC(C)(C)OC(=O)N[C@H]1CCCN(c2c(C#N)c3nc[nH]c(=O)c3n2-c2ccccc2)C1>>CC(C)(C)OC(=O)N[C@H]1CCCN(c2c(C#N)c3ncn(Cc4nccc5ccccc45)c(=O)c3n2-c2ccccc2)C1,,CN(C)C=O,,Br,O=C([O-])[O-].[K+].[K+],test
US20030032657A1,C[S-].O=Cc1cc(F)c(F)c(F)c1>>CSc1c(F)cc(C=O)cc1F,,C1CCOC1,,O,,test
US20120114696A1,CCOC(=O)Cc1cc(C(=O)c2ccc3cc(-c4ccc(C(=O)OCc5ccccc5)cc4)[nH]c3c2)sc1Br.O=C1c2ccccc2C(=O)N1CCCCBr>>CCOC(=O)Cc1cc(C(=O)c2ccc3cc(-c4ccc(C(=O)OCc5ccccc5)cc4)n(CCCCN4C(=O)c5ccccc5C4=O)c3c2)sc1Br,,CC#N,,[Cs+].[F-],,test
US20060252812A1,C=O.CCCCCN1C(=O)C(c2cc(F)ccc2O)c2ccccc21>>CCCCCN1C(=O)C(CO)(c2cc(F)ccc2O)c2ccccc21,,C1CCOC1,CCOC(C)=O,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20100152210A1,Clc1nc(Cl)c2c(ncn2Cc2ccccc2)n1.NC1CCCCC1>>Clc1nc(NC2CCCCC2)c2c(ncn2Cc2ccccc2)n1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20080176862A1,COc1cccc(C=O)c1.SCCCS>>COc1cccc(C2SCCCS2)c1,,ClCCl,,,,test
US05728686,BrCc1ccccc1.CCOCn1cnc2c1c(=O)[nH]c(=O)n2C>>CCOCn1cnc2c1c(=O)n(Cc1ccccc1)c(=O)n2C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050032790A1,CS(=O)(=O)n1ccc2cc(F)c(O)cc21.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CS(=O)(=O)n1ccc2cc(F)c(OS(=O)(=O)C(F)(F)F)cc21,,ClCCl,,c1ccncc1,,test
US20160158207A1,Cc1cccc(Nc2n[nH]c3c2CN(C(=O)OC(C)(C)C)CC3)c1>>Cc1cccc(Nc2n[nH]c3c2CNCC3)c1,,CCOC(C)=O,,Cl,,test
US20070244092A1,CC(C)(C)c1nc2cc(S(=O)(=O)n3ccc(C(=O)O)c3)ccc2n1CC1CCOCC1.NCC(F)F>>CC(C)(C)c1nc2cc(S(=O)(=O)n3ccc(C(=O)NCC(F)F)c3)ccc2n1CC1CCOCC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130203745A1,Clc1cccc(Cl)c1Nc1ccc(C2CN(Cc3ccccc3)CCO2)cc1>>Clc1cccc(Cl)c1Nc1ccc(C2CNCCO2)cc1,,ClCCCl,,CC(Cl)OC(=O)Cl,,test
US20110294776A1,CC1(C)C(=O)N(Br)C(=O)N1Br.Nc1ncnn2c(C(=O)CCl)ccc12>>Nc1ncnn2c(C(=O)CCl)cc(Br)c12,,CN(C)C=O,,,,test
US04788206,COC(=O)/C=C/C=C(/c1ccccc1)c1ccc(OC)cc1>>COc1ccc(/C(=C\C=C\C(=O)O)c2ccccc2)cc1,,CO,,[Na+].[OH-],,test
US20140031360A1,CC(C)(C)OC(=O)NC1CCN(c2cncc(-c3nn(C4CCCCO4)c4ccc(Br)cc34)n2)CC1.OB(O)c1cccc(F)c1>>CC(C)(C)OC(=O)NC1CCN(c2cncc(-c3nn(C4CCCCO4)c4ccc(-c5cccc(F)c5)cc34)n2)CC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20080260649A1,Cc1cc([N+](=O)[O-])ccc1-n1c(=O)n(-c2ccc([N+](=O)[O-])cc2C)c(=O)n(-c2ccc([N+](=O)[O-])cc2C)c1=O>>Cc1cc(N)ccc1-n1c(=O)n(-c2ccc(N)cc2C)c(=O)n(-c2ccc(N)cc2C)c1=O,[Pd],C1CCOC1,,Cl,O,test
US20070249665A1,CN(C)C=O.COc1ccc2c(Cl)nc(C)c(Br)c2c1>>COc1ccc2c(Cl)nc(C)c(C=O)c2c1,,C1CCOC1,,[Li]CCCC,,test
US20100298336A1,Cc1cc(O)nc(SCc2ccncc2)n1.Cl>>Cc1cc(O)nc(SCc2ccncc2)n1.Cl,,CO,,C1COCCO1,,test
US20050107386A1,COc1ccc2cc(C(=O)c3cc(C#N)ccc3F)ccc2c1>>N#Cc1ccc(F)c(C(=O)c2ccc3cc(O)ccc3c2)c1,,ClCCl,,BrB(Br)Br,,test
US20040198793A1,BrBr.COc1cc(C(=O)CCCC2CCCCC2)c(OC)cc1Cl>>COc1cc(C(=O)C(Br)CCC2CCCCC2)c(OC)cc1Cl,,ClCCl,,O,,test
US20030162797A1,CC(C)C(=O)Cl.N#CCC#N>>CC(C)C(O)=C(C#N)C#N,,C1CCOC1,,[H-].[Na+],,test
US20090318424A1,CCCNC(=O)c1ccc(C)c(-c2nc(NCCCN(CC)C(=O)OC(C)(C)C)nc3c2CNC(=O)N3c2c(F)cccc2F)c1.O=C(O)C(F)(F)F>>CCCNC(=O)c1ccc(C)c(-c2nc(NCCCNCC)nc3c2CNC(=O)N3c2c(F)cccc2F)c1.O=C(O)C(F)(F)F,,ClCCl,,[Na+].[OH-],,test
US20060135578A1,CCOP(=O)(CP(=O)(OCC)OCC)OCC.COc1cc(COc2nn(-c3ccccc3)cc2C=O)ccc1OCc1nc(-c2cccnc2)oc1C>>CCOP(=O)(/C=C/c1cn(-c2ccccc2)nc1OCc1ccc(OCc2nc(-c3cccnc3)oc2C)c(OC)c1)OCC,,O,,CN(C)C=O,[H-].[Na+],test
US20070004772A1,Cc1nc(C(F)(F)F)ccc1CCl.N#Cc1ccc(-c2ccn3c(=O)[nH]nc3c2Br)cc1>>Cc1nc(C(F)(F)F)ccc1Cn1nc2c(Br)c(-c3ccc(C#N)cc3)ccn2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050054712A1,Cc1cc(C2(O)C(=O)N(Cc3ccccc3)c3ccccc32)cc(C)c1O[Si](C)(C)C(C)(C)C>>Cc1cc(C2(O)C(=O)N(Cc3ccccc3)c3ccccc32)cc(C)c1O,,C1CCOC1,,CCOC(C)=O,,test
US20080070929A1,C#CCBr.Nc1ccc2c(c1)OC(F)(F)C(F)(F)O2>>C#CCNc1ccc2c(c1)OC(F)(F)C(F)(F)O2,,CC#N,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20100069346A1,O=S(Cl)Cl.OC[C@@H]1COCCN1Cc1ccccc1>>ClC[C@@H]1COCCN1Cc1ccccc1,CN(C)C=O,ClCCl,,,,test
US20130059856A1,CNCc1ccncc1.COC(=O)C(=O)Cl>>COC(=O)C(=O)N(C)Cc1ccncc1,,ClCCl,,c1ccncc1,,test
US20050234046A1,COC(=O)CO.O=S(=O)(c1cccc(CBr)c1)N1CCN(c2ccc(C(F)(F)F)cc2)CC1>>COC(=O)COCc1cccc(S(=O)(=O)N2CCN(c3ccc(C(F)(F)F)cc3)CC2)c1,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20030078251A1,CC(=O)Cl.COc1cccc([C@H]2O[C@H](CC(=O)NCCCCC(=O)O)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC>>COc1cccc([C@H]2O[C@H](CC(=O)NCCCCC(=O)O)C(=O)N(CC(C)(C)COC(C)=O)c3ccc(Cl)cc32)c1OC,,O,,CCOC(C)=O,c1ccncc1,test
US20130274244A1,Cc1cccc(Cn2nc(I)c3c([N+](=O)[O-])cccc32)n1>>Cc1cccc(Cn2ncc3c(N)cccc32)n1,[Zn],CO,,[Cl-].[NH4+],,test
US20100292253A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1sc(-c2cncc(F)c2)nc1F>>CC(C)(C)OC(=O)Nc1sc(-c2cncc(F)c2)nc1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130029961A1,CC(C)(C)[Si](C)(C)Cl.Nc1ccncc1CO>>CC(C)(C)[Si](C)(C)OCc1cnccc1N,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US20120329780A1,COc1ccc(Cn2cc3nc(C4CCN(C)CC4)nc(Cl)c3n2)cc1.Nc1ccc2cn[nH]c2c1>>CN1CCC(c2nc(Nc3ccc4cn[nH]c4c3)c3[nH]ncc3n2)CC1,C1COCCO1,CO,,Cl,,test
US20040058903A1,CC(C)(C)OC(=O)Nc1cccc(CCNC(=O)c2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2)n1>>Nc1cccc(CCNC(=O)c2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090048239A1,COCOc1cc(OS(=O)(=O)c2ccc(C)cc2)ccc1-c1[nH]c2cc(C(=O)OC)ccc2c1C1CCCCC1>>COCOc1cc(O)ccc1-c1[nH]c2cc(C(=O)OC)ccc2c1C1CCCCC1,,CO,,Cl,C[O-].[Na+],test
US20020019388A1,Cc1cc(N2C[C@H]3CN(C(=O)OCc4ccccc4)C[C@H]32)cnc1Cl>>Cc1cc(N2C[C@H]3CNC[C@H]32)cnc1Cl,,O=C(O)C(F)(F)F,,,,test
US20060287343A1,BrCc1cccc(Br)c1.COCCN>>COCCNCc1cccc(Br)c1,,COCCOC,,CCN(CC)CC,,test
US20090318408A1,COc1cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)c(F)cc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C>>COc1cc(C(=O)NC2CCNCC2)c(F)cc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120226036A1,O=C1CCC(=O)N1Br.OCc1ccc(-c2nccs2)cc1>>BrCc1ccc(-c2nccs2)cc1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,O=C([O-])O.[Na+],test
US20140171446A1,CC(C)I.Nc1cnc(-c2cc(O)ccc2Cl)cn1>>CC(C)Oc1ccc(Cl)c(-c2cnc(N)cn2)c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05624950,COc1ccccc1C1(O)CCC(C)(C)C2CN(C(=O)OC(C)(C)C)CC21.Cl>>COc1ccccc1C1(O)CCC(C)(C)C2CNCC21.Cl,,C1COCCO1,,,,test
US20040082607A1,CC(C)Cn1c(CNC(=O)OC(C)(C)C)c(-c2cccc(F)c2)c2cc(O)ccc2c1=O.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)Cn1c(CNC(=O)OC(C)(C)C)c(-c2cccc(F)c2)c2cc(OS(=O)(=O)C(F)(F)F)ccc2c1=O,,CN(C)C=O,,O,[H-].[Na+],test
US05290630,CI.COc1ccc(OC)c(NCCCC#N)c1>>COc1ccc(OC)c(N(C)CCCC#N)c1,,CCO,O,CCN(CC)CC,,test
US20100222328A1,Cc1nc2sccn2c1C(=O)NC[C@@H]1CCCCN1C(=O)OC(C)(C)C.Cl>>Cc1nc2sccn2c1C(=O)NC[C@@H]1CCCCN1.Cl,,C1COCCO1,,,,test
US20050004189A1,CCOC(=O)C[C@H](Cc1csc(CCCCNc2cc(N3CCOCC3)ccn2)n1)c1ccc2c(c1)OCO2.Cl>>Cl.O=C(O)C[C@H](Cc1csc(CCCCNc2cc(N3CCOCC3)ccn2)n1)c1ccc2c(c1)OCO2,,C1CCOC1,,Cl,[Li+].[OH-],test
US04617417,COC(=O)Cl.COc1ccc(N)cc1OC>>COC(=O)Nc1ccc(OC)c(OC)c1,,ClCCl,,O,[Na+].[OH-],test
US05153201,COc1cccc(C=Cc2nc3c(s2)NCCC3)c1OC.CS(=O)(=O)Cl>>COc1cccc(C=Cc2nc3c(s2)N(S(C)(=O)=O)CCC3)c1OC,,c1ccncc1,,O=C([O-])O.[Na+],,test
US20140378686A1,Clc1cc2c(cc1Cl)CC=C2.Fc1cc(Br)c2c(c1)C=CC2.O>>OC1c2cc(Cl)c(Cl)cc2CC1Br,,CS(C)=O,,,,test
US20020198200A1,C[Si](C)(C)N[Si](C)(C)C.O=C(O)C(OC1CCCC1)c1ccc(Cl)c(Cl)c1>>NC(=O)C(OC1CCCC1)c1ccc(Cl)c(Cl)c1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20110166122A1,CC1(O)CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)C1.Cl>>CC1(O)CN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)C1.Cl,,C1COCCO1,,CO,,test
US20120295897A1,CC(C)CCN1C(=O)C2(COc3cc(OCc4ccccc4)ccc32)c2ccccc21>>CC(C)CCN1C(=O)C2(COc3cc(O)ccc32)c2ccccc21,[Pd],CO,,,,test
US20080139586A1,CC(C)Cc1nc2cnccc2c(=O)o1.NCc1ccccc1>>CC(C)Cc1nc2cnccc2c(=O)n1Cc1ccccc1,,ClC(Cl)Cl,,[Na+].[OH-],,test
US20150218170A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Clc1nc2[nH]ccc2nc1Br>>CC(C)(C)OC(=O)n1ccc2nc(Br)c(Cl)nc21,CN(C)c1ccncc1,CC#N,,,,test
US20120225867A1,Cc1c(C=O)ccc(C#N)c1Cl.NO>>Cc1c(/C=N/O)ccc(C#N)c1Cl,,C1CCOC1,,Cl,c1ccncc1,test
US20080214615A1,CNCc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O.O=C=Nc1cccc(Cl)c1>>CN(Cc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O)C(=O)Nc1cccc(Cl)c1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20110166169A1,O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1cccc2[nH]c3ccccc3c12>>O=S(=O)(Oc1cccc2[nH]c3ccccc3c12)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20140018347A1,Cc1nc(N)nc(Cl)c1C(C)C.O=C(Nc1nc2ncc(-c3ccc4c(c3)CNCCO4)cc2[nH]1)OCc1ccccc1>>Cc1nc(N)nc(N2CCOc3ccc(-c4cnc5[nH]c(N)nc5c4)cc3C2)c1C(C)C,,CN1CCCC1=O,O,CCN(C(C)C)C(C)C,Cl,test
US20160060230A1,N#Cc1ccc(C(Cl)N=C=O)c(F)c1.O=C1C=C(Nc2cccc(C(F)(F)F)c2)CC1>>N#Cc1ccc(C2NC(=O)N(c3cccc(C(F)(F)F)c3)C3=C2C(=O)CC3)c(F)c1,,ClCCl,,,,test
US05844102,C=C[Mg]Br.c1ccc(CO[C@@H]2[C@H]3CO[C@H](O3)[C@H]3O[C@@H]23)cc1>>C=C[C@H]1[C@@H]2OC[C@@H](O2)[C@@H](OCc2ccccc2)[C@@H]1O,,C1CCOC1,,[Cl-].[NH4+],,test
US20160229816A1,CCOC(OCC)c1cccc(CP(=O)(OCC)OCC)c1.CCOc1ccc(C=O)cc1>>CCOc1ccc(/C=C/c2cccc(C=O)c2)cc1,,C1CCOC1,,CC(C)(C)O[Na],,test
US20120220569A1,CC(=O)OCC(=O)Cl.CC(C)(C)OC(=O)NCCCN>>CC(=O)OCC(=O)NCCCNC(=O)OC(C)(C)C,,C1CCOC1,,CCN(CC)CC,O,test
US20130079321A1,COCCN(CCOC)S(F)(F)F.Cn1ncc([N+](=O)[O-])c1N1CCC(O)C(N=[N+]=[N-])CC1>>Cn1ncc([N+](=O)[O-])c1N1CCC(F)C(N=[N+]=[N-])CC1,,C1CCOC1,ClCCl,O=C([O-])O.[Na+],,test
US20100331317A1,CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN3C(=O)c4ccccc4C3=O)ccc21>>CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN)ccc21,,CO,,NN,O,test
US20030153596A1,CSC(=NC#N)NCc1ccc(C(C)(C)C)cc1.NCCc1ccccn1>>CC(C)(C)c1ccc(CNC(=NC#N)NCCc2ccccn2)cc1,,Cc1ccccc1C,,,,test
US20140155407A1,CC(C)C(O)c1ccc(-c2ccoc2)nc1.O=C(n1ccnc1)n1ccnc1>>CC(C)C(OC(=O)n1ccnc1)c1ccc(-c2ccoc2)nc1,,CC#N,,,,test
US20060074056A1,CSc1cc2ncnc(Oc3ccc([N+](=O)[O-])cc3F)c2s1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1cc2ncnc(Oc3ccc([N+](=O)[O-])cc3F)c2s1,,ClCCl,,,,test
US06891044B2,C[Si](C)(C)CCOCn1nc(C=Cc2ccccc2)c2c(C(O)c3ccccc3)cccc21>>C[Si](C)(C)CCOCn1nc(C=Cc2ccccc2)c2ccc(C(=O)c3ccccc3)cc21,,CCCCCC,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20050113340A1,COc1cc(C(=O)Cl)cc(OC)c1OC.Nc1nc(Cl)c2nc[nH]c2n1>>COc1cc(C(=O)n2cnc3c(Cl)nc(N)nc32)cc(OC)c1OC,,c1ccncc1,,,,test
US05891889,CCOC(=O)C1(Cc2cc(C)nc(Cl)c2)CCN(C(=O)OC(C)(C)C)CC1>>CCOC(=O)C1(Cc2ccnc(C)c2)CCN(C(=O)OC(C)(C)C)CC1,[Pd],CO,,[H][H],,test
US20110269810A1,NCCCCCN.O=C1c2c(Cl)cccc2-c2n[nH]c3cccc1c23>>NCCCCCNc1cccc2c1C(=O)c1cccc3[nH]nc-2c13,,CS(C)=O,,,,test
US20140256704A1,Clc1ccnc2[nH]ncc12.O=C1CCC(=O)N1Br>>Clc1ccnc2[nH]nc(Br)c12,,CC(=O)O,,,,test
US20040058956A1,OCCC=Cc1ccc(OCc2ccccc2)cc1>>OCCCCc1ccc(O)cc1,[Pd],C1CCOC1,CO,[H][H],,test
US06001997,Cc1ccc(C(=O)O)o1>>CC1CCC(C(=O)O)O1,[Rh],CCOC(C)=O,,[H][H],,test
US06498161B1,CC(C)(C)OC(=O)N1CCC2(CCC(=O)O2)CC1.Fc1ccc(CBr)cc1>>CC(C)(C)OC(=O)N1CCC2(CC1)CC(Cc1ccc(F)cc1)C(=O)O2,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20020016328A1,CCC(CC)Nc1cc(C)nc(Cl)c1C(=O)OC.Cc1ccccc1N(C)C>>CCC(CC)Nc1cc(C)nc(Nc2c(C)cc(C)cc2C)c1C(=O)OC,[Cu],,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US06130222,CC(=O)Cl.CCN(CC)C(=O)c1ccc(C(c2ccccc2)N2CCNCC2)cc1.Cl>>CCN(CC)C(=O)c1ccc(C(c2ccccc2)N2CCN(C(C)=O)CC2)cc1.Cl,,ClCCl,,CCN(CC)CC,Cl,test
US05155122,CC(C)(C)c1cc(C(=O)NN)cc(C(C)(C)C)c1O.CN=C=O>>Cn1c(-c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)n[nH]c1=O,,CCO,,[Na+].[OH-],,test
US04472305,CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C)C(N)=O>>CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCCN1)C(N)=O,,CC(=O)O,,Cl,,test
US05112977,CCC(C)O.O=C1c2ccc(F)cc2C(=O)c2cc3ccccc3cc21>>C=CCCOc1ccc2c(c1)C(=O)c1cc3ccccc3cc1C2=O,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04751295,COC(=O)C(=NOC1CCCC1)c1nsc(NC(=O)OC(C)(C)C)n1>>CC(C)(C)OC(=O)Nc1nc(C(=NOC2CCCC2)C(=O)O)ns1,,CO,,[Na+].[OH-],,test
US20030078236A1,BrP(Br)Br.OCc1ccccc1SCc1ccccc1>>BrCc1ccccc1SCc1ccccc1,,CCOCC,,,,test
US20070293530A1,COCCO.Nc1nc(-c2ccc(O)cc2)cs1>>COCCOc1ccc(-c2csc(N)n2)cc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050277630A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)OCCC(Br)C3=O)C(=O)O1.NC(N)=S>>Br.CC(=O)NC[C@H]1CN(c2ccc3c(c2)OCCc2sc(N)nc2-3)C(=O)O1,,CCO,,,,test
US20100105906A1,CC(=O)OCCBr.O=C(c1cccnc1Oc1cc(Cl)ccc1Cl)N1CCNc2ccccc21>>CC(=O)OCCN1CCN(C(=O)c2cccnc2Oc2cc(Cl)ccc2Cl)c2ccccc21,,CN(C)C=O,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120035409A1,CC(N)=CC#N.O=C1CCC(=O)C1.O=Cc1ccc2[nH]ncc2c1>>CC1=C(C#N)C(c2ccc3[nH]ncc3c2)C2=C(CCC2=O)N1,,CCO,,C1CCNCC1,,test
US20120316147A1,CC(C#N)(CC1CC1)NC(=O)OC(C)(C)C.NO>>CC(C)(C)OC(=O)NC(C)(CC1CC1)C(=N)NO,,CCO,O,Cl,O=C([O-])O.[Na+],test
US20130331419A1,COC(=O)C(Br)c1ccc(Cl)cc1.O=Cc1cccc2[nH]ccc12>>COC(=O)C(c1ccc(Cl)cc1)n1ccc2c(C=O)cccc21,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20130303507A1,CCOC(=O)C(C)(C)Br.N#CC1(CNc2cccc(-c3cc(N[C@@H]4CC[C@@H](CN)CC4)ncc3Cl)n2)CCOCC1>>CCOC(=O)C(C)(C)NC[C@@H]1CC[C@@H](Nc2cc(-c3cccc(NCC4(C#N)CCOCC4)n3)c(Cl)cn2)CC1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,,test
US20120015962A1,CCOC(=O)c1ccc(C(=O)OC)[nH]1.Cc1cc(C)c(S(=O)(=O)NO)c(C)c1>>CCOC(=O)c1ccc(C(=O)OC)n1N,,CN(C)C=O,,[H-].[Na+],,test
US04528114,CCCCCc1ccc(-c2ccc(CC[C@@H]3CC[C@@H](C=C(Br)Br)CC3)cc2)cc1>>C#C[C@@H]1CC[C@@H](CCc2ccc(-c3ccc(CCCCC)cc3)cc2)CC1,,C1CCOC1,CCCCCC,O,[Li]CCCC,test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(C(C)N4CCN(S(C)(=O)=O)CC4)cnc3Nc3cnc(OC)c(F)c3)n2)cc1>>COc1ncc(Nc2ncc(C(C)N3CCN(S(C)(=O)=O)CC3)cc2-c2nc(C)nc(N)n2)cc1F,,O=C(O)C(F)(F)F,,,,test
US06140351,COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CCl)c1Cl.NCC(F)(F)F>>COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CNCC(F)(F)F)c1Cl,,CN(C)C=O,,,,test
US20120129806A1,CC(=O)N[C@@]1(C(=O)NC(C)(C)C)CNC[C@@H]1CCCB1OC(C)(C)C(C)(C)O1.CC(C)(C)OC(=O)N(CC=O)Cc1ccc(Cl)c(Cl)c1>>N[C@@]1(C(=O)O)CN(CCNCc2ccc(Cl)c(Cl)c2)C[C@@H]1CCCB(O)O,,ClCCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20110028738A1,CC(=O)OCc1sc2ccccc2c(=O)c1I>>O=c1c(I)c(CO)sc2ccccc12,,CO,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US06498254B1,CC(=O)OO.Cc1ccc(CS(=O)c2cccc[n+]2[O-])cc1[N+](=O)[O-]>>Cc1ccc(CS(=O)(=O)c2cccc[n+]2[O-])cc1[N+](=O)[O-],,CC(=O)O,,,,test
US20110144105A1,Cc1ccc(S(=O)(=O)OC(=CC(C)C)c2cc3cccnc3n2S(=O)(=O)c2ccccc2)cc1.OB(O)c1cccc(Cl)c1>>CC(C)C=C(c1cccc(Cl)c1)c1cc2cccnc2n1S(=O)(=O)c1ccccc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US20020183351A1,C1=C(c2c[nH]c3ccccc23)CCNC1.Cc1nc2c3c(ccc2[nH]1)OC[C@H](CCl)O3>>Cc1nc2c3c(ccc2[nH]1)OCC(CN1CC=C(c2c[nH]c4ccccc24)CC1)O3,,CCOC(C)=O,CS(C)=O,,,test
US20100197683A1,CCCCC(=O)CC(=O)OC.N#Cc1ccccc1-c1ccc(CBr)cc1F>>CCCCC(=O)C(Cc1ccc(-c2ccccc2C#N)c(F)c1)C(=O)OC,,C1CCOC1,,[H-].[Na+],,test
US20030036612A1,CC1Cc2sc(-c3ccccc3)c(-c3ccccc3)c2C1=O>>CC1Cc2sc(-c3ccccc3)c(-c3ccccc3)c2C1O,,CCOCC,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20120071461A1,CC(C)CS(=O)(=O)Cl.COC(=O)c1ccc2c(c1)[C@H](N)CC2>>COC(=O)c1ccc2c(c1)[C@H](NS(=O)(=O)CC(C)C)CC2,,ClCCl,,CCN(CC)CC,,test
US20060089349A1,C=CC(=O)Cl.CC1(C)CC2CC(C)(CN2C(=O)c2ccc(N)cc2)C1>>C=CC(=O)Nc1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cc1,,C1CCOC1,,,,test
US09345708B2,Cc1ccc(S(=O)(=O)n2cc(-c3ncc(F)c(N[C@@H]4CCC[C@@](OC(=O)[O-])(N5C(=O)CCC5=O)C4)n3)c3cc(F)cnc32)cc1.F[C@@H]1CCNC1>>Cc1ccc(S(=O)(=O)n2cc(-c3ncc(F)c(N[C@@H]4CCC[C@H](OC(=O)N5CC[C@@H](F)C5)C4)n3)c3cc(F)cnc32)cc1,,CC#N,,,,test
US08691982B2,CC(C)c1cnn2c(NCc3ccc(-c4ccccn4)cc3)nc(N[C@@H](CO)[C@H](C)O)nc12.O=C(O)/C=C/C(=O)O>>CC(C)c1cnn2c(NCc3ccc(-c4ccccn4)cc3)nc(N[C@@H](CO)[C@H](C)O)nc12.O=C(O)/C=C/C(=O)O,,CCO,CCOCC,,,test
US05117050,COS(=O)(=O)OC.Nc1ccc(S(=O)(=O)O)c(N)c1>>CNc1cc(N)ccc1S(=O)(=O)O,,O,O=CO,O=S(=O)(O)O,[Na+].[OH-],test
US06197729B1,C=C(c1ccc(OC)cc1)C(F)(F)F>>CC(c1ccc(O)cc1)C(F)(F)F,[Pd],CC(=O)O,,,,test
US20040116508A1,O=C(O)c1ccccc1S.Oc1ccc(O)cc1>>O=c1c2ccccc2sc2c(O)ccc(O)c12,,O=S(=O)(O)O,,Cl,O=C([O-])O.[Na+],test
US20160213679A1,CCCN(CCC)S(=O)(=O)c1ccc(N)cc1.Cc1c(C(=O)Cl)cnn1-c1ccccc1>>CCCN(CCC)S(=O)(=O)c1ccc(NC(=O)c2cnn(-c3ccccc3)c2C)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20060079533A1,C[Si](C)(C)CCOC(=O)OC1CN(C(=O)OCC[Si](C)(C)C)CCC1c1cccc(Br)c1>>OC1CNCCC1c1cccc(Br)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05405861,C[C@H](OC1CCCCO1)C(O)(Cn1cncn1)c1ccc(F)cc1F>>C[C@H](O)[C@@](O)(Cn1cncn1)c1ccc(F)cc1F,,CCO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US04181802,NC(N)=O.Nc1ccccc1NCc1cccnc1>>O=c1[nH]c2ccccc2n1Cc1cccnc1,,CO,ClC(Cl)Cl,,,test
US20120213806A1,C[C@@](CO)(C[C@H](N)Cc1ccc(-c2ccccc2)cc1)C(=O)OC1COC1.O=C(O)c1c[nH]nn1>>C[C@@](CO)(C[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)c1cnn[nH]1)C(=O)OC1COC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130317026A1,C1COCCN1.Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(C=O)nc3)cc3c2cnn3C2CCCC2)c(=O)[nH]1>>Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(CN4CCOCC4)nc3)cc3c2cnn3C2CCCC2)c(=O)[nH]1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20100222339A1,CCCC(CCC)c1cc(C)nc2c(-c3sc(-c4ncnn4C)nc3Br)c(C)nn12.Cl>>CCCC(CCC)c1cc(C)nc2c(-c3sc(-c4ncnn4C)nc3Br)c(C)nn12.Cl,,CC(C)=O,,CCOCC,,test
US20110028442A1,CC(C)OC(C)C.CCOCC.NCCc1cccc(NC(=O)NCc2ccc(F)cc2)c1>>NCCc1cccc(NC(=O)NCC23CC4CC(CC(C4)C2)C3)c1,,CCOCC,,CC#N,,test
US05075299,COc1ccc(COc2c(CO)oc(C)cc2=O)cc1.NO>>COc1ccc(COc2c(CO)n(O)c(C)cc2=O)cc1,,c1ccncc1,,Cl,,test
US20130090340A1,CC(C)(C)N=C=O.N#Cc1c(-c2ccccc2)c(F)n2c1CNCC2>>CC(C)(C)NC(=O)N1CCn2c(F)c(-c3ccccc3)c(C#N)c2C1,,ClCCl,,CCN(CC)CC,O,test
US20050096377A1,CCOC(=O)c1c(-c2ccc3[nH]ccc3c2)c2cc(N)ccc2n1Cc1ccccc1.O=S(=O)(Cl)c1ccccc1>>O=C(O)c1c(-c2ccc3[nH]ccc3c2)c2cc(NS(=O)(=O)c3ccccc3)ccc2n1Cc1ccccc1,,CC#N,,,,test
US20100029753A1,CC(C)(C)c1ccc(S(=O)(=O)O)c(I)c1.ClP(Cl)(Cl)(Cl)Cl>>CC(C)(C)c1ccc(S(=O)(=O)Cl)c(I)c1,,CC(Cl)Cl,,,,test
US20040058820A1,CC(=O)C(Cc1ccc(Cl)cc1)c1ccccc1>>CC(O)C(Cc1ccc(Cl)cc1)c1ccccc1,,CO,,[BH4-].[Na+],,test
US20100298290A1,Cc1ccc2ncnc(N3CCOc4ccc(-c5cnc6[nH]c(NC(=O)OCc7ccccc7)nc6c5)cc4C3)c2c1>>Cc1ccc2ncnc(N3CCOc4ccc(-c5cnc6[nH]c(N)nc6c5)cc4C3)c2c1,[Pd],CC(=O)O,,[H][H],,test
US20050148645A1,CC(C)NC(=N)N.CSC1=NC(=O)C(=O)N1c1ccc(Cl)c(Cl)c1>>CC(C)NC(=N)NC1=NC(=O)C(=O)N1c1ccc(Cl)c(Cl)c1,,CN(C)C=O,,,,test
US05250679,C=CCN(CC(O)Cc1ccccc1)C(=O)c1cc(I)ccc1O>>C=CCN1CC(Cc2ccccc2)Oc2ccc(I)cc2C1=O,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05464922,C=CCCBr.CCOC(=O)c1ccc(C(=O)OCC)c(O)c1>>C=CCCOc1cc(C(=O)OCC)ccc1C(=O)OCC,,CN(C)C=O,,[Na+].[OH-],,test
US20050038101A1,CCOC(=O)c1cc2cc(NC(=O)CC(C)(C)C)ccc2n1Cc1ccccc1C(F)(F)F>>CC(C)(C)CC(=O)Nc1ccc2c(c1)cc(C(=O)O)n2Cc1ccccc1C(F)(F)F,,C1CCOC1,CO,[Li+].[OH-],,test
US20160229853A1,CC(C)(C)[Si](C)(C)Cl.OCc1cc2cc(Cl)cc(F)c2[nH]1>>CC(C)(C)[Si](C)(C)OCc1cc2cc(Cl)cc(F)c2[nH]1,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US05198925,C=C(F)C(=O)Cl.OC(c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F>>C=C(F)C(=O)OC(c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F,,CCOCC,,CCN(CC)CC,,test
US20020006922A1,CCOC(=O)C(C)Br.COc1ccc(S)cc1>>CCOC(=O)C(C)Sc1ccc(OC)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04249937,C=CCON.CCCC(=O)C1C(=O)CC(CCSC)CC1=O>>C=CCONC(CCC)=C1C(=O)CC(CCSC)CC1=O,,CCO,,,,test
US20120015942A1,CN(C)CCCl.COC(=O)C1CCc2ccc(-c3cccc(O)c3)cc2C1>>COC(=O)C1CCc2ccc(-c3cccc(OCCN(C)C)c3)cc2C1,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20070124152A1,CC(=O)OC(C)=O.CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN(C)C(=O)OCc2ccccc2)c1=O>>CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN(C)C(C)=O)c1=O,[Pd],ClCCl,,CCN(C(C)C)C(C)C,,test
US20070167443A1,COc1ccc(C(=O)c2c[nH]c3ccccc3c2=O)cc1F.FC(F)(F)c1cccc(CBr)n1>>COc1ccc(C(=O)c2cn(Cc3cccc(C(F)(F)F)n3)c3ccccc3c2=O)cc1F,,O,,CN(C)C=O,,test
US20140080808A1,CC(C)n1cc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO[Si](C)(C)C(C)(C)C)C5)CC3)cc2)cn1>>CC(C)n1cc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO)C5)CC3)cc2)cn1,,CO,,Cl,,test
US20090048241A1,CS(=O)(=O)OCCOC(c1ccc(C#N)cc1)c1cnc[nH]1>>N#Cc1ccc(C2OCCn3cncc32)cc1,,CC#N,,,,test
US06359009B1,CCOC(=O)C(C)(C)SC(C)C>>CC(C)SC(C)(C)C(=O)O,,CCO,O,[K+].[OH-],,test
US20130165483A1,CI.COC(=O)c1[nH]c(Cl)cc1Cl>>COC(=O)c1c(Cl)cc(Cl)n1C,,C1CCOC1,O,[H-].[Na+],,test
US20070067921A1,CCCCCCCCCCCOc1cccc(C(=O)O)c1.O=C(Cl)C(=O)Cl>>CCCCCCCCCCCOc1cccc(C(=O)Cl)c1,CN(C)C=O,ClCCl,,Cc1ccccc1,,test
US20090163524A1,CC(C)(C)OC(=O)NC1(C(=O)O)CCN(c2ncnc3[nH]ccc23)CC1.COC(=O)C[C@H](N)c1ccc(Cl)cc1>>COC(=O)C[C@H](NC(=O)C1(NC(=O)OC(C)(C)C)CCN(c2ncnc3[nH]ccc23)CC1)c1ccc(Cl)cc1,,CCOC(C)=O,CN1CCCC1=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070167433A1,COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CC(O)C3c3ccc(OC4CCN(c5cccc(F)c5)C4)cc3)cc21.CS(=O)(=O)Cl>>COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CC(OS(C)(=O)=O)C3c3ccc(OC4CCN(c5cccc(F)c5)C4)cc3)cc21,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US04053594,CC(=O)C(Cl)C(C)=O.Cl.NC(N)=O>>Cc1nc(O)nc(C)c1Cl.Cl,,CCO,Cl,,,test
US20090163520A1,Nc1ncnc2c1cnn2-c1ccc([N+](=O)[O-])cc1>>Nc1ccc(-n2ncc3c(N)ncnc32)cc1,[Pd],CCO,,,,test
US09273028B2,CC(C)(C)OC(=O)N1CCC[C@@H](Nc2ncnc3c2cnn3COCC[Si](C)(C)C)C1.Cl>>Cl.c1nc(N[C@@H]2CCCNC2)c2cn[nH]c2n1,,C1COCCO1,,,,test
US20020198376A1,CC(=O)SCCN(CCc1ccccc1)C(=O)N[C@@H](C)C(=O)N1CCN(C)CC1>>C[C@H](NC(=O)N(CCS)CCc1ccccc1)C(=O)N1CCN(C)CC1,,CO,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[Na+].[OH-],test
US20060069109A1,CI.O=Cc1[nH]cnc1-c1ccccc1>>Cn1cnc(-c2ccccc2)c1C=O,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20030078276A1,COC(CBr)OC.O=c1cc(Cl)[nH]c(=O)n1Cc1ccccc1.[SH-]>>COC(CSc1cc(=O)n(Cc2ccccc2)c(=O)[nH]1)OC,,CN(C)C=O,,O,,test
USRE039591E1,O=C1c2ccccc2C(=O)N1O.OCc1cnc2ccccc2c1>>O=C1c2ccccc2C(=O)N1OCc1cnc2ccccc2c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(N2CCc3ccccc3C2)nc1-c1ccc(C)cc1>>CCCC(C(=O)O)c1c(C)nc(N2CCc3ccccc3C2)nc1-c1ccc(C)cc1,,CO,,[Na+].[OH-],,test
US20150376181A1,CC1(c2cccc(F)c2)NC(=O)c2c(Cl)cc(Nc3cc(NC(=O)C4CC4)ncn3)c(=O)n21.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>O=c1c(Nc2ccncn2)ccc2n1C1(CCCCC1)NC2=S,,CO,ClCCl,C1CCOC1,,test
US05200422,CC(=O)Cl.Nc1ccc2oc(=O)[nH]c2c1>>CC(=O)Nc1ccc2oc(=O)[nH]c2c1,,C1CCOC1,,CCN(CC)CC,,test
US20110130409A1,CCOC(=O)CC1CCc2c1[nH]c1ccc(OCc3ccc(C(F)(F)F)cc3C(F)(F)F)cc21>>O=C(O)CC1CCc2c1[nH]c1ccc(OCc3ccc(C(F)(F)F)cc3C(F)(F)F)cc21,,C1COCCO1,O,[Na+].[OH-],,test
US20080015146A1,c1ccc(C(c2ccccc2)N2CC(n3cccn3)C2)cc1>>c1cnn(C2CNC2)c1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20090076147A1,C=C[C@H](OCc1ccccc1)C(C)(C)CO.O=C1c2ccccc2C(=O)N1CCCS(=O)(=O)Cl>>C=C[C@H](OCc1ccccc1)C(C)(C)COS(=O)(=O)CCCN1C(=O)c2ccccc2C1=O,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20080045496A1,COc1ccc(B(O)O)cn1.O=C(OCc1ccccc1)N1C=C(OS(=O)(=O)C(F)(F)F)CC1>>COc1ccc(C2=CN(C(=O)OCc3ccccc3)CC2)cn1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20100190826A1,CCOC(=O)c1cccc(-n2c(Cl)nc3cc(C(F)(F)F)ccc32)c1.CO>>COC(=O)c1cccc(-n2c(OC)nc3cc(C(F)(F)F)ccc32)c1,,CO,,C[O-].[Na+],,test
US20100160309A1,CCCCOc1nccc2nc(C(C)C)c3ccc(F)cc3c12>>CC(C)c1nc2cc[nH]c(=O)c2c2cc(F)ccc12,,C1CCOC1,,Cl,,test
US20040058903A1,C=Cc1ccccn1.O=[N+]([O-])c1ccc(S)cc1>>O=[N+]([O-])c1ccc(SCCc2ccccn2)cc1,,CO,,CC(=O)O,,test
US05104888,Cc1c(C)c2c(c(C)c1OCCO)C=CC(C)(COc1ccc(CC3SC(=O)NC3=O)cc1)O2>>Cc1c(C)c2c(c(C)c1OCCO)CCC(C)(COc1ccc(CC3SC(=O)NC3=O)cc1)O2,[Pd],CCO,,,,test
US04125612,CC(=O)c1ccc(-c2ccc(Cl)cc2)cc1>>CC(O)c1ccc(-c2ccc(Cl)cc2)cc1,,CO,,[BH4-].[Na+],,test
US20140315933A1,N#Cc1cc(S(=O)(=O)Cl)ccc1F.Nc1nncs1>>N#Cc1cc(S(=O)(=O)Nc2nncs2)ccc1F,,ClCCl,,c1ccncc1,,test
US20140024656A1,NNC(=O)c1ccccc1.S=C=S>>Sc1nnc(-c2ccccc2)o1,,CCO,,[K+].[OH-],,test
US20150133422A1,CC(C)(C)OC(=O)N1CCC(n2cc(-c3c[nH]c4cc(F)ccc34)cn2)CC1>>Fc1ccc2c(-c3cnn(C4CCNCC4)c3)c[nH]c2c1,,C1COCCO1,,Cl,,test
US20110269737A1,COc1c(NC(=O)c2cc3cccc(CN4CCN(C(=O)[C@H]5CCN(C(=O)OC(C)(C)C)C5)CC4)c3n2C)cc(C(C)(C)C)cc1NS(C)(=O)=O>>COc1c(NC(=O)c2cc3cccc(CN4CCN(C(=O)[C@H]5CCNC5)CC4)c3n2C)cc(C(C)(C)C)cc1NS(C)(=O)=O,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20040082607A1,CC(C)Cn1c(CNC(=O)OC(C)(C)C)c(-c2ccc(F)cc2)c2cc(O)ccc2c1=O.NC(=O)CI>>CC(C)Cn1c(CNC(=O)OC(C)(C)C)c(-c2ccc(F)cc2)c2cc(OCC(N)=O)ccc2c1=O,,CN(C)C=O,,C1CCC2=NCCCN2CC1,O,test
US20090137595A1,N#CC1(c2cccc(C(=O)O)c2)CC1.Nc1cccc(Sc2ccc3nc(NC(=O)C4CC4)cn3n2)c1>>N#CC1(c2cccc(C(=O)Nc3cccc(Sc4ccc5nc(NC(=O)C6CC6)cn5n4)c3)c2)CC1,CN(C)C=O,CC(=O)N(C)C,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US04199517,C=CC(=O)Cl.CC(C)(c1ccccc1)c1ccccc1O>>C=CC(=O)Oc1ccccc1C(C)(C)c1ccccc1,,Cc1ccccc1,,O=C([O-])[O-].[Ca+2],,test
US06326359B1,COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CN(C)C4CCCCC4)nc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C>>COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CN(C)C4CCCCC4)nc32)[C@H](O)[C@@H]1O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100099665A1,CC(C)(C)OC(=O)N1CCNC[C@@H]1CO.O=c1[nH]cc(S(=O)(=O)Cl)c2cc(Br)ccc12>>CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2c[nH]c(=O)c3ccc(Br)cc23)C[C@@H]1CO,,C1CCOC1,,CCN(CC)CC,,test
US20090156592A1,CC(C)(C)OC(=O)N1CCC(c2nc(C=O)cs2)CC1.Cl>>Cl.O=Cc1csc(C2CCNCC2)n1,,ClCCl,,CCOCC,,test
US20110218197A1,ClCCl.Cn1nc(C(C)(C)C)cc1-c1nc2cc(-c3ccccc3C(F)(F)F)nc(Cl)c2[nH]1>>Cn1nc(C(C)(C)C)c(Cl)c1-c1nc2cc(-c3ccccc3C(F)(F)F)nc(Cl)c2[nH]1,,CO,,,,test
US20070254909A1,COC(=O)Cc1ccncc1C#N>>N#Cc1cnccc1CCO,,CCO,CCOC(C)=O,[BH4-].[Na+],[Cl-].[NH4+],test
US04665075,O=c1[nH]c2cc(O)ccc2c(=O)n1CCCCN1CCC(C2(c3ccc(F)cc3)OCCO2)CC1>>O=c1[nH]c2cc(O)ccc2c(=O)n1CCCCN1CCC(Cc2ccc(F)cc2)CC1,,CCO,,Cl,N,test
US20150031685A1,CC(=O)OC(C)=O.CN(C(=O)OCc1ccccc1)[C@H](CN1CC[C@H](O[Si](C)(C)C(C)(C)C)C1)c1cccc(C(=N)NO)c1>>Cc1nc(-c2cccc([C@@H](CN3CC[C@H](O)C3)N(C)C(=O)OCc3ccccc3)c2)no1,,Cc1ccccc1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130143860A1,CC(=O)Cl.OCC1CCCN1>>CC(=O)N1CCCC1CO,,ClCCl,,[K+].[OH-],,test
US20030186984A1,CN(c1ncc(Br)cn1)[C@@H]1CC[C@@H](C#CCOS(C)(=O)=O)CC1.CNC>>CN(C)CC#C[C@@H]1CC[C@@H](N(C)c2ncc(Br)cn2)CC1,,CO,,,,test
US07691855B2,COc1cc(-c2n[nH]cc2-c2ccnc(Nc3cccc(S(N)(=O)=O)c3)n2)ccc1Cl>>NS(=O)(=O)c1cccc(Nc2nccc(-c3c[nH]nc3-c3ccc(Cl)c(O)c3)n2)c1,,ClCCl,,BrB(Br)Br,,test
US20050096336A1,CCOC(=O)COc1ccc(N(C)C(=O)OC(C)(C)C)c2ccccc12>>CCOC(=O)COc1ccc(NC)c2ccccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US04205170,CCOC(=O)C(C)c1ccc2c(c1)C(=O)Cc1ccccc1O2>>CC(C(=O)O)c1ccc2c(c1)C(=O)Cc1ccccc1O2,,CCO,O,[K+].[OH-],,test
US20070149542A1,CI.CS(=O)(=O)c1cccc(C2CCNCC2)c1F>>CN1CCC(c2cccc(S(C)(=O)=O)c2F)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120046285A1,CC(=O)NC1CCN(CCC(=O)O)CC1.COc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CN)c3Cl)cccc2n1Cc1ccccn1>>COc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)CCN4CCC(NC(C)=O)CC4)c3Cl)cccc2n1Cc1ccccn1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100298325A1,CN(C)c1cccc(Oc2ccc(Cl)nc2)c1.COc1cccc(N)c1>>COc1cccc(Nc2ccc(Oc3cccc(N(C)C)c3)cn2)c1,,C1COCCO1,CCOC(C)=O,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20080153828A1,BrBr.COC(=O)c1cccc2cc(C)sc12>>COC(=O)c1cccc2c(Br)c(C)sc12,,ClC(Cl)Cl,ClCCl,,,test
US20040058978A1,CC(=O)OC(C)=O.NCc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1>>CC(=O)NCc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1,,CC(=O)O,,,,test
US04426382,CC(C)CCO.COc1cc2nc(Cl)nc(N)c2cc1OC.O=C(c1cccc(OCc2ccccc2)c1)N1CCNCC1>>COc1cc2nc(N3CCN(C(=O)c4cccc(OCc5ccccc5)c4)CC3)nc(N)c2cc1OC.Cl.O,,CC(C)CCO,,,,test
US20070249670A1,COC(=O)[C@@H](NC(=O)c1ccc(F)cc1N)[C@@H](C)OC(C)(C)C.Cc1cc(C)c(N=C=O)c(C)c1>>COC(=O)[C@@H](NC(=O)c1ccc(F)cc1NC(=O)Nc1c(C)cc(C)cc1C)[C@@H](C)OC(C)(C)C,,c1ccncc1,,CCCCCC,CCOC(C)=O,test
US20130231319A1,CCOC(=O)C=C1CCN(C(=O)OC(C)(C)C)CC1(F)F>>CCOC(=O)CC1CCN(C(=O)OC(C)(C)C)CC1(F)F,[Pd],CCO,,,,test
US20040186160A1,COc1ccc2c(c1)NC(=O)C2.O=Cc1[nH]c2c(c1CCC(=O)O)CCCCC2>>COc1ccc2c(c1)NC(=O)/C2=C\c1[nH]c2c(c1CCC(=O)O)CCCCC2,,CCO,,C1CCNCC1,,test
US04956368,CCCCCCCCCC(=O)Cl.O=C1CC2(CCC(O)C2)CC(=O)N1CCCCBr>>CCCCCCCCCC(=O)OC1CCC2(CC(=O)N(CCCCBr)C(=O)C2)C1,,CC#N,,,,test
US20160115126A1,C#CC(=O)O.Cc1[nH]c2c(C(N)=O)ccc(NC3CCNC3)c2c1C>>C#CC(=O)N1CCC(Nc2ccc(C(N)=O)c3[nH]c(C)c(C)c23)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05405861,CC(n1cncn1)C1(c2ccc(F)cc2F)CO1.COC(=O)CCS>>CC(n1cncn1)C(O)(CS)c1ccc(F)cc1F,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20040267012A1,Cc1ccc(C(=O)NC2CC2)cc1B1OC(C)(C)C(C)(C)O1.O=C(NCC1CC1)c1ccc(Br)cc1F>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC2CC2)c(F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(C)O,,O=C([O-])O.[Na+],,test
US20040142981A1,CCOC(=O)OCC.NC(=NO)c1cc(Br)ccc1N>>Nc1ccc(Br)cc1-c1noc(=O)[nH]1,,CCO,,C[O-].[Na+],,test
US20100286087A1,CCOc1cc2c(c(F)c1OCC)C(N)=NC2.COc1c(N2CCOCC2)cc(C(=O)CBr)cc1C(C)(C)C>>Br.CCOc1cc2c(c(F)c1OCC)C(=N)N(CC(=O)c1cc(N3CCOCC3)c(OC)c(C(C)(C)C)c1)C2,,C1CCOC1,,,,test
US06630488B1,CC(C)(C)OC(=O)NCCCOc1ccc2cc(C(=O)O)cc(=O)n2c1.O=C(O)C(F)(F)F>>NCCCOc1ccc2cc(C(=O)O)cc(=O)n2c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US04243682,CCOC(C)=O.COc1ccc2cc(C(C)=O)cc(F)c2c1>>COc1ccc2cc(C(O)=CC(C)=O)cc(F)c2c1,,COCCOC,,O,[H-].[Na+],test
US20050261284A1,CSc1ncc(Br)c(N(C)N)n1.O=C(Cl)c1c(Cl)cccc1Cl>>CSc1ncc(Br)c(N(C)NC(=O)c2c(Cl)cccc2Cl)n1,,CCN(CC)CC,ClCCl,,,test
US20040127574A1,CC(C)I.O=C(NC(Cc1cccc(OC(F)(F)C(F)F)c1)C(O)c1ccc(O)cc1)c1cccc2c1C=CCCC2>>CC(C)Oc1ccc(C(O)C(Cc2cccc(OC(F)(F)C(F)F)c2)NC(=O)c2cccc3c2C=CCCC3)cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20110015157A1,COCc1ccc([C@H](C)N2CC[C@](CCCO[Si](C)(C)C(C)(C)C)(c3ccccc3)OC2=O)cc1>>COCc1ccc([C@H](C)N2CC[C@](CCCO)(c3ccccc3)OC2=O)cc1,,CCOC(C)=O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090062518A1,CC(C)c1[nH][nH]c(=O)c1Cc1ccccc1.O=C(OCc1ccccc1)ON1C(=O)CCC1=O>>CC(C)c1c(Cc2ccccc2)c(=O)[nH]n1C(=O)OCc1ccccc1,,CN(C)C=O,,CCOC(C)=O,O,test
US20150087646A1,CC(C)(CO)C(=O)NCc1cnc(C(F)F)c(-c2nn(-c3ccc(C(F)(F)F)cc3)c(=O)[nH]2)c1.CCN(CC)S(F)(F)F>>CC(C)(CF)C(=O)NCc1cnc(C(F)F)c(-c2nn(-c3ccc(C(F)(F)F)cc3)c(=O)[nH]2)c1,,ClCCl,,,,test
US04094906,CCCC(=O)OC(=O)CCC.NNc1c(Cl)cc(Cl)cc1Cl>>CCCC(=O)N(N)c1c(Cl)cc(Cl)cc1Cl,,c1ccccc1,,,,test
US20090286778A1,O=C(/C=C/c1cccc([N+](=O)[O-])c1)c1cccc([N+](=O)[O-])c1>>Nc1cccc(CCCc2cccc(N)c2)c1,[Pd],CN(C)C=O,,CC(=O)O,,test
US20110136834A1,CC(C)(C)[Si](C)(C)Cl.CC1(C)O[C@@H]2[C@@H](CO)O[C@@H](n3cnc4c(Cl)ncnc43)[C@@H]2O1>>CC1(C)O[C@@H]2[C@@H](CO[Si](C)(C)C(C)(C)C)O[C@@H](n3cnc4c(Cl)ncnc43)[C@@H]2O1,,CN(C)C=O,,c1c[nH]cn1,,test
US20130040931A1,Cc1cccc(C#N)c1Br.Cc1ccccc1[Mg]Br.O>>Cc1ccccc1C(=O)c1cccc(C)c1Br,,C1CCOC1,O,CCOCC,Cl,test
US04579848,Clc1ccnc(-c2cccc(I)c2)n1.NN>>NNc1ccnc(-c2cccc(I)c2)n1,,O,,,,test
US20050065160A1,COC(=O)CC1c2cccc(F)c2N=C(N2CCN(c3cccc(OC)c3)CC2)N1c1cc(C(F)(F)F)ccc1OC>>COc1cccc(N2CCN(C3=Nc4c(F)cccc4C(CC(=O)O)N3c3cc(C(F)(F)F)ccc3OC)CC2)c1,,C1COCCO1,,[Na+].[OH-],,test
US20090118292A1,COCCOc1cc(C(N)=O)cc(C(=O)OC)c1>>COCCOc1cc(C#N)cc(C(=O)OC)c1,,ClCCCl,,O=P(Cl)(Cl)Cl,,test
US20100197711A1,CC(=O)c1ccc(-c2cccc(S(N)(=O)=O)c2)o1.O=C(O)CCCc1ccccc1>>CC(=O)c1ccc(-c2cccc(S(=O)(=O)NC(=O)CCCc3ccccc3)c2)o1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20060235247A1,C=CCCl.CCCCCC.CCOC(C)=O.Clc1ccccc1.O=C=O>>C=CCC1(O)C(=CC)CC2CC1C2(C)C,,C1CCOC1,,,,test
US20090004209A1,COC(=O)c1cccc(O)c1C(=O)OC.ClCc1ccc(Cl)s1>>COC(=O)c1cccc(OCc2ccc(Cl)s2)c1C(=O)OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04002640,N#CCSc1ccc(N)c([N+](=O)[O-])c1>>N#CCSc1ccc(N)c(N)c1,[Fe],O,,CO,,test
US20060194969A1,CC(=O)OCc1nc2c(N)cc(Br)cc2n1C.Cc1cccc(C)c1CCl>>CC(=O)OCc1nc2c(NCc3c(C)cccc3C)cc(Br)cc2n1C,,CC#N,O,[I-].[K+],,test
US20100261728A1,FC(F)(F)c1ccc([C@H]2NCCc3ccccc32)cc1.O=C(Nc1ccc(Cl)nc1)Oc1ccc([N+](=O)[O-])cc1>>O=C(Nc1ccc(Cl)nc1)N1CCc2ccccc2[C@H]1c1ccc(C(F)(F)F)cc1,,Cc1ccccc1,,CS(C)=O,,test
US04308277,CCI.COc1ccc([C@@H]2NC(=S)N[C@@H]2c2ccc(OC)cc2)cc1>>CCSC1=N[C@@H](c2ccc(OC)cc2)[C@@H](c2ccc(OC)cc2)N1,,CN(C)C=O,CO,O,[Na],test
US04439438,CC(C)C(=O)Cl.C[N+](C)(C)CC(O)CC(=O)[O-]>>CC(C)C(=O)C(O)(CC(=O)[O-])C[N+](C)(C)C,,O=C(O)C(F)(F)F,,CC(C)=O,,test
US20070197619A1,CCOC(=O)Cc1cn(-c2ccc(Cl)cc2)c(CN(C)c2ccc(F)cc2)n1>>CN(Cc1nc(CC(=O)O)cn1-c1ccc(Cl)cc1)c1ccc(F)cc1,,C1CCOC1,O,[Na+].[OH-],,test
US20110319406A1,C1COCCN1.O=[N+]([O-])c1cccc(CBr)c1F>>O=[N+]([O-])c1cccc(CN2CCOCC2)c1F,,Cc1ccccc1,,,,test
US20070197512A1,C=CC(=O)OC.CC(C)C1Oc2ccccc2NC1=O>>COC(=O)CCN1C(=O)C(C(C)C)Oc2ccccc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130281433A1,Cc1ccc(S(=O)(=O)n2cc(I)c3cc(Br)cnc32)cc1.OB(O)c1cccnc1>>Cc1ccc(S(=O)(=O)n2cc(-c3cccnc3)c3cc(Br)cnc32)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,ClCCl,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US20030018034A1,Brc1cnc(N2CCNCC2)s1.CC(=O)NCc1ccc(CCl)cc1>>CC(=O)NCc1ccc(CN2CCN(c3ncc(Br)s3)CC2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050143422A1,CC(C)[C@H](NS(=O)(=O)c1ccc(-c2ccc(NC(=O)c3cc4cc(N)ccc4o3)cc2)cc1)C(=O)O.CS(=O)(=O)Cl>>CC(C)[C@H](NS(=O)(=O)c1ccc(-c2ccc(NC(=O)c3cc4cc(NS(C)(=O)=O)ccc4o3)cc2)cc1)C(=O)O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US06180625B2,Cc1ccc(N)c(C(=O)O)c1.O=C(Cl)c1ccccc1OC(F)(F)F>>Cc1ccc2nc(-c3ccccc3OC(F)(F)F)oc(=O)c2c1,,Cc1ccccc1,,CCN(CC)CC,,test
US05521170,[N-]=[N+]=NCc1ccccc1-c1ccccc1C(=O)Nc1ccc(C(=O)N2CCCc3ccccc32)cc1>>NCc1ccccc1-c1ccccc1C(=O)Nc1ccc(C(=O)N2CCCc3ccccc32)cc1,[Pd],C1COCCO1,CO,[H][H],,test
US20050272784A1,CCOC(=O)C(Cc1ccc(Cl)cc1)NC(=O)c1cc(-c2ccc(-c3ccccc3)cc2)nn1-c1cccc(C(F)(F)F)c1>>O=C(NC(Cc1ccc(Cl)cc1)C(=O)O)c1cc(-c2ccc(-c3ccccc3)cc2)nn1-c1cccc(C(F)(F)F)c1,,C1CCOC1,,[Na+].[OH-],,test
US20130324546A1,COc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1ncc(C(F)(F)F)c(C#Cc2cccc(C(N)=O)c2)n1>>COc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1ncc(C(F)(F)F)c(CCc2cccc(C(N)=O)c2)n1,[Pd],CN(C)C=O,,,,test
US09434726B2,CC(C)(C)OC(=O)NC[C@@H]1CCN(c2nc(-c3ccc(N4CCOCC4)cc3)cc3nccnc23)C1.CI>>CN(C[C@@H]1CCN(c2nc(-c3ccc(N4CCOCC4)cc3)cc3nccnc23)C1)C(=O)OC(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20100249123A1,COc1ccc(C(=O)Nc2ccc(C(C)(C)C#N)c(Br)c2)cc1OC.OB(O)c1cncnc1>>COc1ccc(C(=O)Nc2ccc(C(C)(C)C#N)c(-c3cncnc3)c2)cc1OC,,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US04595470,O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1.O=C(O)c1ccc(Cl)cc1C(=O)O.O=CO.[C]=O.[OH-]>>O=C(O)c1cc(C(=O)O)c(C(=O)O)cc1C(=O)O.O=C(O)c1cc(C(=O)O)c(C(=O)O)cc1Cl,,[Na+],[OH-],,,test
US20110077240A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COCCOCCOCCNCc1ccc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)cc1>>COCCOCCOCCN(Cc1ccc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)cc1)C(=O)OC(C)(C)C,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CO,,test
US20070032531A1,CSc1ccc(CN)cc1.O=C(O)c1nc(-c2ccc(Cl)cc2)cs1>>CSc1ccc(CNC(=O)c2nc(-c3ccc(Cl)cc3)cs2)cc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20160046648A1,Cl.FC(F)(F)c1ccccc1C1CCNCC1>>Cl.FC(F)(F)c1ccccc1C1CCNCC1,,CC#N,,C1COCCO1,,test
US20090131398A1,CCN(CC)[C@@H]1C[C@@H](CN2C(=O)C(O[Si](CC)(CC)CC)(c3ccc(Cl)cc3Cl)c3c2cc(I)cc3C(F)(F)F)C1.c1c[nH]nn1>>CCN(CC)[C@@H]1C[C@@H](CN2C(=O)C(O)(c3ccc(Cl)cc3Cl)c3c2cc(-n2ccnn2)cc3C(F)(F)F)C1,I[Cu]I,CN(C)C=O,O,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20090076070A1,CC(Oc1ccc(-c2nc(-c3cccc4c3ccn4CC(=O)NCc3ccccn3)no2)cc1C(F)(F)F)C(F)(F)F.Cl>>CC(Oc1ccc(-c2nc(-c3cccc4c3ccn4CC(=O)NCc3ccccn3)no2)cc1C(F)(F)F)C(F)(F)F.Cl,,ClCCl,,C1COCCO1,,test
US20150266878A1,O=C1NC(=O)c2ccccc21.OC[C@H](Nc1cncc(Br)c1)c1ccccc1>>O=C1c2ccccc2C(=O)N1C[C@H](Nc1cncc(Br)c1)c1ccccc1,,C1CCOC1,O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090239854A1,CC1CCCCN1.CN1CCc2c(c3cc(Cl)ccc3n2CC(=O)O)C1>>CC1CCCCN1C(=O)Cn1c2c(c3cc(Cl)ccc31)CN(C)CC2,CN(C)c1ccncc1,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20080090856A1,CC(C)c1cc(NC(=O)Nc2cc(Oc3ccc([N+](=O)[O-])nc3)ccc2F)n(-c2ccc3ncccc3c2)n1>>CC(C)c1cc(NC(=O)Nc2cc(Oc3ccc(N)nc3)ccc2F)n(-c2ccc3ncccc3c2)n1,[Zn],CO,,[Cl-].[NH4+],,test
US20080207708A1,OCc1cccc2[nH]c(-c3csc(Cc4cc(Cl)ccc4OCc4ccccc4)n3)nc12>>O=Cc1cccc2[nH]c(-c3csc(Cc4cc(Cl)ccc4OCc4ccccc4)n3)nc12,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US03987182,CC(C)C(=O)N(C)c1cc(C(F)(F)F)ccc1[N+](=O)[O-]>>CC(C)c1nc2ccc(C(F)(F)F)cc2n1C,[Pd],CCO,,,,test
US20140142083A1,CC=O.COC(=O)c1cc(F)cc(NC2C[C@@H](C)N(Cc3ccccc3)[C@H](C)C2)c1C>>CCN(c1cc(F)cc(C(=O)OC)c1C)C1C[C@@H](C)N(Cc2ccccc2)[C@H](C)C1,,CC(=O)O,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070249670A1,COC(=O)[C@@H](NC(=O)c1ccc(-c2ccccc2)cc1[N+](=O)[O-])C1CCCCC1>>COC(=O)[C@@H](NC(=O)c1ccc(-c2ccccc2)cc1N)C1CCCCC1,[Pd],CCO,,,,test
US20110269738A1,COc1c(CC=O)cc(F)cc1-c1nnc(-c2ccc(CC(C)C)c(C#N)c2)s1.O=C(O)C1CNC1>>COc1c(CCN2CC(C(=O)O)C2)cc(F)cc1-c1nnc(-c2ccc(CC(C)C)c(C#N)c2)s1,,ClCCl,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090270374A1,COc1cnc2ccc(=O)n(CCN3CCC(NC(=O)OC(C)(C)C)CC3)c2c1.Cl.ClC(Cl)Cl>>COc1cnc2ccc(=O)n(CCN3CCC(N)CC3)c2c1.Cl.Cl,,C1COCCO1,ClC(Cl)Cl,CO,,test
US06602882B1,CCCCCCCI.OC1CCNCC1>>CCCCCCCN1CCC(O)CC1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20140057902A1,CCCC[Sn](CCCC)(CCCC)c1ccccc1.COc1cccc(C2=NCC(=O)N3CCc4c(I)cccc4C3=C2)c1>>COc1cccc(C2=NCC(=O)N3CCc4c(cccc4-c4ccccc4)C3=C2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US04379167,CCC(O)C(Cl)Oc1ccccc1Cl.Cl.O.c1ccc2c(c1)CCNC2>>Cl.O.OC(CCC1NCCc2ccccc21)COc1ccccc1Cl,,CCCCO,,,,test
US20030087922A1,CCC(C#N)OP(=O)([O-])[O-].COc1cc(C(C)=O)cc(OC)c1OC>>COc1cc(C(C)=CC#N)cc(OC)c1OC,,C1CCOC1,,[H-].[Na+],,test
US20140018533A1,CCOC(=O)C1=C(Nc2ccc(C(C)C)cc2)OC(=Cc2c[nH]c3ncccc23)C1=O>>CC(C)c1ccc(NC2=CC(=O)C(=Cc3c[nH]c4ncccc34)O2)cc1,,CN(C)C=O,,,,test
US20080009530A1,CC(C)OCCN.O=C=NS(=O)(=O)Cl.OCCCc1ccc(OCc2ccco2)cc1Oc1ncc(C(F)(F)F)cc1Cl>>CC(C)OCCNS(=O)(=O)NC(=O)OCCCc1ccc(OCc2ccco2)cc1Oc1ncc(C(F)(F)F)cc1Cl,,Cc1ccccc1,O,c1ccncc1,,test
US04311699,CC(=O)N[C@H](C)C(=O)Nc1ccc(-c2ncc(C(=O)O)c(O)n2)cc1.O=C(n1ccnc1)n1ccnc1>>CC(=O)N[C@H](C)C(=O)Nc1ccc(-c2ncc(C(=O)O)c(O)n2)cc1.c1c[n-]cn1,,CC#N,,CN(C)C=O,,test
US20040176410A1,COC(=O)c1ccc(OCC2(O)CCNCC2)cc1.N#Cc1ccc(CC=O)cc1>>COC(=O)c1ccc(OCC2(O)CCN(CCc3ccc(C#N)cc3)CC2)cc1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04711895,OC1C=CC(O)(CCCCOc2ccccc2)C1>>O=C1C=CC(O)(CCCCOc2ccccc2)C1,,CCOCC,ClCCl,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US05472983,CC(C)(C)C(=O)Cl.Nc1ccccc1>>CC(C)(C)C(=O)Nc1ccccc1,,c1ccccc1,,,,test
US20100197914A1,CCc1nnn([C@@H]2C=C[C@H](n3cnc4c(Cl)nc(Cl)nc43)C2)n1.CO[C@H]1CCC[C@@H]1N>>CCc1nnn([C@@H]2C=C[C@H](n3cnc4c(N[C@H]5CCC[C@@H]5OC)nc(Cl)nc43)C2)n1,,C1CCOC1,,,,test
US20160024110A1,CC(C)Br.Oc1cc(Br)ccc1F>>CC(C)Oc1cc(Br)ccc1F,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US04054586,Nc1cccc2c1C(=O)c1ccccc1C2=O>>O=C1c2ccccc2C(=O)c2ccccc21,,O,,,,test
US04740233,COC(CC(C)=O)OC.Nc1n[nH]c(SCc2ccccc2)n1>>Cc1ccnc2nc(SCc3ccccc3)nn12,,CC(=O)O,,,,test
US04478849,COC(=O)c1ccc(CCN)cc1.O=CC(=O)c1ccccc1>>COC(=O)c1ccc(CCNCC(O)c2ccccc2)cc1,,O,,c1ccccc1,,test
US20140113922A1,CSc1nc(=O)c(Cc2cnc(=O)[nH]c2)c[nH]1.NCCc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cc1>>O=c1ncc(Cc2c[nH]c(NCCc3ccc(Oc4ccc(Cl)c(C(F)(F)F)c4)cc3)nc2=O)c[nH]1,,c1ccncc1,,,,test
US20080108648A1,COc1cc(C(=O)c2ncc3ccc(C(=O)O)cn23)ccc1[N+](=O)[O-].N>>COc1cc(C(=O)c2ncc3ccc(C(N)=O)cn23)ccc1[N+](=O)[O-],,C1CCOC1,CN(C)C=O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20050143422A1,CCOC(=O)c1oc2cccc(C#N)c2c1C.OO>>CCOC(=O)c1oc2cccc(C(N)=O)c2c1C,,CCO,CS(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US20130252944A1,CCC(O)c1nn(Cc2ccc(OC)cc2)cc1-c1nc(N)sc1CO>>CCC1OCc2sc(N)nc2-c2cn(Cc3ccc(OC)cc3)nc21,,ClCCl,O=C(O)C(F)(F)F,,,test
US20030069257A1,CCNc1cc(C(C)=O)ccc1N.N=C(N)CCl>>CCn1c(CCl)nc2ccc(C(C)=O)cc21,,CC#N,,Cl,,test
US20060040999A1,COc1ccc(C(C)(C)O)c(F)c1OC>>COc1ccc(C(C)C)c(F)c1OC,[Pd],CCO,Cl,,,test
US20100087417A1,CCO.O=C(O)c1cc(Cl)nc(Cl)c1>>CCOC(=O)c1cc(Cl)nc(Cl)c1,,O=S(=O)(O)O,,,,test
US20150057265A1,CCOC(=O)Cc1ncc(Br)cc1F.COc1ccc(CN=C=S)cc1>>CCOC(=O)c1c(NCc2ccc(OC)cc2)sc2cc(Br)cnc12,,CS(C)=O,,O,[H-].[Na+],test
US20120022043A1,N.O=C(Nc1ccnn1-c1cccc(C(F)(F)F)c1)c1cnn2ccc(Cl)nc12>>Nc1ccn2ncc(C(=O)Nc3ccnn3-c3cccc(C(F)(F)F)c3)c2n1,,CCO,,,,test
US20060189623A1,CC1(C)OB(C2=CCOCC2)OC1(C)C.CN1CCN(c2ccc([N+](=O)[O-])c(Br)c2)CC1>>CN1CCN(c2ccc([N+](=O)[O-])c(C3=CCOCC3)c2)CC1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20090270450A1,CC(C)(C)[Si](C)(C)OCC=O.CCOC(=O)c1cnc2cc(OC)c(C3CCNCC3)cc2c1Nc1ccc(C)cc1F>>CCOC(=O)c1cnc2cc(OC)c(C3CCN(CCO[Si](C)(C)C(C)(C)C)CC3)cc2c1Nc1ccc(C)cc1F,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20120149662A1,CC(C)(C)C(=O)OCn1ccc2c(-c3cnn([C@H](CCO)C4CCCC4)c3)cnnc21.CS(=O)(=O)Cl>>CC(C)(C)C(=O)OCn1ccc2c(-c3cnn([C@H](CCOS(C)(=O)=O)C4CCCC4)c3)cnnc21,CN(C)c1ccncc1,ClCCl,,,,test
US20050215577A1,CC(C)(C)OC(=O)OC(C)(C)C.CNC(=O)C(F)(C1CCc2c([nH]c3ccc(Cl)cc23)C1)S(=O)(=O)c1ccccc1>>CNC(=O)C(F)(C1CCc2c(n(C(=O)OC(C)(C)C)c3ccc(Cl)cc23)C1)S(=O)(=O)c1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20140110642A1,CC(C)(C)C#Cc1nc(C(C)(C)C)ccc1C=O.NCCN>>CC(C)(C)c1ccc2c(cc(C(C)(C)C)n3ccnc23)n1,,O=[N+]([O-])c1ccccc1,,,,test
US06130187,CCc1cc2c(Cl)cc(F)c(-n3c(=O)cc(C(F)(F)F)[nH]c3=O)c2o1.CI>>CCc1cc2c(Cl)cc(F)c(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c2o1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120309752A1,CC(C)(C)OC(=O)N1CC2CN(c3nc(C4=NOC(c5c(F)cccc5F)C4)cs3)CC2C1>>Fc1cccc(F)c1C1CC(c2csc(N3CC4CNCC4C3)n2)=NO1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04409215,O=C(CON1C(=O)c2ccccc2C1=O)OC(c1ccccc1)c1ccccc1>>NOCC(=O)OC(c1ccccc1)c1ccccc1,,CO,ClCCl,NN,O,test
US20140275097A1,COC(=O)c1cccc(C)n1.NN>>Cc1cccc(C(=O)NN)n1,,CCO,,O,,test
US20160122341A1,Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(C#C[Si](C)(C)C)n2c1>>C#Cc1c(C)nc2c(OCc3c(F)cccc3F)cc(C)cn12,,CO,,O=C([O-])[O-].[K+].[K+],,test
US05409809,Fc1c(F)c(F)c(CBr)c(F)c1F.Sc1nc2ccccc2s1>>Fc1c(F)c(F)c(CSc2nc3ccccc3s2)c(F)c1F,,CCO,,[Na+].[OH-],,test
US05438141,C=C[Mg]Br.O=Cc1cccc(C=Cc2ccc3cc(F)c(F)cc3n2)c1>>C=CC(O)c1cccc(C=Cc2ccc3cc(F)c(F)cc3n2)c1,,C1CCOC1,Cc1ccccc1,,,test
US20090192204A1,COc1ccc2[nH]cc(CC(=O)O)c2c1.Nc1ncc([N+](=O)[O-])s1>>COc1ccc2[nH]cc(CC(=O)Nc3ncc([N+](=O)[O-])s3)c2c1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20160060257A1,CNS(=O)(=O)Cl.COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCNCC3)cc12>>CNS(=O)(=O)N1CCC(c2cc3c(-c4cc(F)ccc4OC)ccnc3[nH]2)CC1,,ClCCl,,CCN(CC)CC,,test
US05051413,C=CC1OC=NC1C(=O)OCC.O>>C=CC(O)C(NC=O)C(=O)OCC,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US05998412,BrCC1CC1.C[Si](C)(C)CCS(=O)(=O)n1cc(C2CCN(S(=O)(=O)N3CCNC[C@@H]3C(=O)NOCc3ccccc3)CC2)c2cc(F)ccc21>>C[Si](C)(C)CCS(=O)(=O)n1cc(C2CCN(S(=O)(=O)N3CCN(CC4CC4)C[C@@H]3C(=O)NOCc3ccccc3)CC2)c2cc(F)ccc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US07683056B2,CC(C)(C)OC(=O)NCN1CCC[C@@H]1CNC(=O)OCc1ccccc1>>O=C(NC[C@H]1CCCN1)OCc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160229816A1,COc1cc(C#N)cc(B2OC(C)(C)C(C)(C)O2)c1.FC(F)(F)c1ccnc(Cl)c1>>COc1cc(C#N)cc(-c2cc(C(F)(F)F)ccn2)c1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20090023725A1,CCNC(=O)c1ccc(C)c(-c2ccc3c(I)n[nH]c3c2)c1.CS(=O)(=O)c1ccc(B(O)O)cc1>>CCNC(=O)c1ccc(C)c(-c2ccc3c(-c4ccc(S(C)(=O)=O)cc4)n[nH]c3c2)c1,,CC(C)O,,O=C([O-])O.[Na+],,test
US20160075713A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.OCC(F)(F)c1ccc(C(F)(F)F)nc1>>O=S(=O)(OCC(F)(F)c1ccc(C(F)(F)F)nc1)C(F)(F)F,,CCOCC,,CCN(C(C)C)C(C)C,,test
US20110178133A1,C[C@@H](N)c1cccc(Cl)c1.O=CC1CC(=O)N(c2ccc(F)cc2)C1>>C[C@@H](NCC1CC(=O)N(c2ccc(F)cc2)C1)c1cccc(Cl)c1,CC(=O)O,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20060135785A1,CCCCCCCCCCCCBr.CCOC(=O)C(c1ccccc1)c1nn[nH]n1>>CCCCCCCCCCCCn1nnc(C(C(=O)OCC)c2ccccc2)n1,,CC#N,,CCN(CC)CC,,test
US20100069349A1,Cn1c(C(C)(C)C)cc(=N)n1CC1CCC1.NS(=O)(=O)c1ccc(F)c(C(=O)O)c1>>Cn1c(C(C)(C)C)c/c(=N\C(=O)c2cc(S(N)(=O)=O)ccc2F)n1CC1CCC1,,C1CCOC1,,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20020099047A1,COc1ccc(CCN2CC[C@@H](N3c4ccccc4COc4ccccc43)C2)cc1.Cl>>COc1ccc(CCN2CC[C@@H](N3c4ccccc4COc4ccccc43)C2)cc1.Cl,,ClCCl,,C1COCCO1,,test
US20160159972A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O,,O=C([O-])O,[Na+],C1CCOC1,,test
US20040006141A1,CCOC(=O)C(Cc1ccc(OCc2ccccc2)cc1)Nc1ccccc1>>CCOC(=O)C(Cc1ccc(O)cc1)Nc1ccccc1,[Pd],C1CCOC1,CCO,,,test
US20090118305A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(Br)cc1-c1nc2c(F)cccc2o1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(B2OC(C)(C)C(C)(C)O2)cc1-c1nc2c(F)cccc2o1,,C1COCCO1,,CC(=O)[O-].[K+],,test
US06359135B1,CCOC(=O)c1ccc(C#Cc2ccc(C3(OCC(C)(C)C)CC3)c(C)c2)cc1>>Cc1cc(CCc2ccc(C(=O)O)cc2)ccc1C1(OCC(C)(C)C)CC1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20050137243A1,ClCCN1CCCC1.O=[N+]([O-])c1ccc2cn[nH]c2c1>>O=[N+]([O-])c1ccc2cnn(CCN3CCCC3)c2c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US04301286,COC(Cl)=NS(=O)(=O)c1ccccc1C.Cc1cc(C)nc(N)n1>>COC(=NS(=O)(=O)c1ccccc1C)Nc1nc(C)cc(C)n1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20150361059A1,CC(C)(S)[C@H](NC(=O)OCc1ccccc1)C(=O)O.O=[N+]([O-])c1ccccc1F>>CC(C)(Sc1ccccc1[N+](=O)[O-])[C@H](NC(=O)OCc1ccccc1)C(=O)O,,CCO,,O,O=C([O-])O.[Na+],test
US20050009841A1,CCOC(C)=O.CO.N#CC1(O)CCN(Cc2ccccc2)CC1>>COC(=O)C1(O)CCN(Cc2ccccc2)CC1,,Cl,,CCCCCC,,test
US20100016401A1,CC(C)(C)OC(=O)N1C[C@H]2C[C@H]2[C@H]1CNC(=O)C(F)(F)F>>O=C(NC[C@H]1NC[C@H]2C[C@H]21)C(F)(F)F,,C1CCOC1,C1COCCO1,Cl,,test
US20070021453A1,CCI.COC(=O)c1cc(O)c2cccc(C3CC3)c2n1>>CCOc1cc(C(=O)OC)nc2c(C3CC3)cccc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04814468,CCOC(=O)C1C(=O)C[C@H]2CC3(C[C@@H]12)OCCO3>>O=C1C[C@H]2CC3(C[C@H]2C1)OCCO3,,CCO,O,Cl,[Na+].[OH-],test
US20130053409A1,C=CC(=O)Cl.COc1cc(N(C)CCN(C)C)c(N)cc1Nc1ncc(C)c(-c2cn(C)c3ccccc23)n1>>C=CC(=O)Nc1cc(Nc2ncc(C)c(-c3cn(C)c4ccccc34)n2)c(OC)cc1N(C)CCN(C)C,,C1CCOC1,O,CCN(C(C)C)C(C)C,,test
US20050043379A1,C[Si](C)(C)N=[N+]=[N-].N#CCCCN(CCc1ccc(Oc2nc3ccccc3s2)cc1)CC1CC1>>c1ccc2sc(Oc3ccc(CCN(CCCc4nn[nH]n4)CC4CC4)cc3)nc2c1,,Cc1ccccc1,ClCCl,C[Al](C)C,,test
US20130302416A1,CCc1cccc(CC)c1NC(=O)c1nn(CCOC2CCCCO2)c2c1CCCc1cnc(Nc3ccc(N4CCN(C)CC4)cc3OC)nc1-2.Cl>>CCc1cccc(CC)c1NC(=O)c1nn(CCO)c2c1CCCc1cnc(Nc3ccc(N4CCN(C)CC4)cc3OC)nc1-2.Cl,,C1COCCO1,CO,,,test
US04743601,CC(N)CO.Clc1ccc2c(Cl)ccnc2c1>>CC(CO)Nc1ccnc2cc(Cl)ccc12,,CCCCO,,ClCCl,O,test
US20110288076A1,Nc1cc(Oc2ccc(F)cc2)ccc1[N+](=O)[O-]>>Nc1ccc(Oc2ccc(F)cc2)cc1N,[Pd],CO,,O=C[O-].[NH4+],,test
US05571774,CCOC(=O)c1ccc[n+]([O-])c1C(=O)OCC.O=[N+]([O-])O>>CCOC(=O)c1cc([N+](=O)[O-])c[n+]([O-])c1C(=O)OCC,,CC(=O)O,,CC(=O)OC(C)=O,,test
US06143764,CCCCc1ccc(N=C=O)cc1.COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC>>CCCCc1ccc(NC(=O)Nc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2)cc1,,Cc1ccccc1,,,,test
US05424451,CN1CCNCC1.O=C1NC(=O)c2c(CCCCCCBr)cccc21>>CN1CCNCC1CCCCCCc1cccc2c1C(=O)NC2=O,,CCOCC,,,,test
US20130012489A1,C1CCNCC1.Clc1nc(Cl)c2ccc(N3CCOCC3)cc2n1>>Clc1nc(N2CCCCC2)c2ccc(N3CCOCC3)cc2n1,,C1CCOC1,,,,test
US20100311734A1,Br.OCc1ccccc1Cc1ccccc1>>BrCc1ccccc1Cc1ccccc1,,O,,,,test
US20040186290A1,CCOC(=O)Cc1cccnc1.ICC1CCCC1>>CCOC(=O)C(CC1CCCC1)c1cccnc1,,C1CCOC1,CN(C)P(=O)(N(C)C)N(C)C,CC(C)[N-]C(C)C.[Li+],,test
US20070208007A1,CCCN(CCC)CCCCN1Cc2ccc(CNCc3ncc[nH]3)cc2C1=O.Cn1ccnc1C=O>>CCCN(CCC)CCCCN1Cc2ccc(CN(Cc3ncc[nH]3)Cc3nccn3C)cc2C1=O,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US20130096113A1,CS(=O)c1nc2ccc(Cn3cnc(Br)c3)cc2s1.N[C@@H]1CCCC[C@H]1O>>O[C@@H]1CCCC[C@H]1Nc1nc2ccc(Cn3cnc(Br)c3)cc2s1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,O,test
US20080051399A1,C=C(C(=O)OC)c1ccc(Cl)cc1.CC(C)(C)N>>COC(=O)C(CNC(C)(C)C)c1ccc(Cl)cc1,,CCO,,C1CCOC1,,test
US20070287839A1,COc1ccc2[nH]c(SCc3ncc(C)c(OC)c3C)nc2c1.O=C(OO)c1cccc(Cl)c1>>COc1ccc2[nH]c(S(=O)Cc3ncc(C)c(OC)c3C)nc2c1,,ClCCl,,[NH4+].[OH-],,test
US06451973B1,CN1CCN(c2ccc(CN(C[C@H](O)[C@H](Cc3ccccc3)NC(=O)C(F)(F)F)NC(=O)OC(C)(C)C)cc2)CC1>>CN1CCN(c2ccc(CN(C[C@H](O)[C@@H](N)Cc3ccccc3)NC(=O)OC(C)(C)C)cc2)CC1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20060247179A1,CC(=O)OC[C@H]1O[C@H](OC(=N)C(Cl)(Cl)Cl)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.Oc1cccc2[nH]cc(CCc3ccccc3)c12>>CC(=O)OC[C@H]1O[C@@H](Oc2cccc3[nH]cc(CCc4ccccc4)c23)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,ClCCl,,,,test
US20160038487A1,CCc1ccc(C(=O)N[C@@H](Cc2ccc(-c3ncc(Br)cn3)cc2)C(=O)OC(C)(C)C)s1>>CCc1ccc(C(=O)N[C@@H](Cc2ccc(-c3ncc(Br)cn3)cc2)C(=O)O)s1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04652558,CCCCn1c(S)nc2ccccc2c1=O.Cl[Sn](c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCn1c(S[Sn](c2ccccc2)(c2ccccc2)c2ccccc2)nc2ccccc2c1=O,,ClCCl,,CCN(CC)CC,,test
US04284634,COC(=O)C1=C(C=O)NC(C)=C(C(=O)OC(C)C)C1c1ccccc1[N+](=O)[O-].NO>>COC(=O)C1=C(C=NO)NC(C)=C(C(=O)OC(C)C)C1c1ccccc1[N+](=O)[O-],,CC(=O)O,,Cl,CC(=O)[O-].[Na+],test
US05929120,CCOC(=O)c1ccc(CCC(=O)CBr)cc1.NC(N)=S>>CCOC(=O)c1ccc(CCc2csc(N)n2)cc1,,CCO,,,,test
US20070244132A1,O=C(OCCOCCO)c1ccccc1.O=C1CCC(=O)N1I>>O=C(OCCOCCI)c1ccccc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,O=C([O-])O.[Na+],test
US20050215691A1,CCBr.CCC1(C)CC(O)C(C)C(C)(CC)N1OC(C)(C)C(=O)NCCCN(C)C>>CCC1(C)CC(O)C(C)C(C)(CC)N1OC(C)(C)C(=O)NCCC[N+](C)(C)CC.[Br-],,CC#N,,,,test
US20080015200A1,CN1CCNCC1.Nc1nc(Cl)c2sc3ccccc3c2n1>>CN1CCN(c2nc(N)nc3c2sc2ccccc23)CC1,,CCO,,,,test
US07253176B1,CC(C)(C)Cn1c(N)cc(=O)[nH]c1=O.COS(=O)(=O)OC>>Cn1c(=O)cc(N)n(CC(C)(C)C)c1=O,,[Na+],[OH-],,,test
US20160060233A1,C=C(C)B1OC(C)(C)C(C)(C)O1.Cc1ccc([N+](=O)[O-])c(Cl)c1>>C=C(C)c1cc(C)ccc1[N+](=O)[O-],Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20070021489A1,CC(C)(C)OC(=O)NCC(=O)c1ccc(OCc2ccccc2)cc1>>CC(C)(C)OC(=O)NCC(=O)c1ccc(O)cc1,[Pd],CO,,,,test
US03962307,CC(=O)OC(C)=O.CCc1cccc(CC)c1N>>CCc1cccc(CC)c1NC(C)=O,,O,,CN(C)C=O,,test
US20040147612A1,O=C1NC(=O)c2ccccc21.O[C@@H]1CCC[C@H]1c1ccccc1>>O=C1c2ccccc2C(=O)N1[C@@H]1CCC[C@@H]1c1ccccc1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US08304419B2,C[Si](C)(C)CCOCn1c(CO)nc(Br)c1C(=O)NCc1ccc(Cl)c(Oc2cc(Cl)cc(C#N)c2)c1F.N>>N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CNC(=O)c3[nH]c(CN)nc3Br)c2F)c1,,CN(C)C=O,CO,CCN(C(C)C)C(C)C,,test
US20150141406A1,COc1nccc2c1c(I)cn2C1CCOC1.N#CCc1ccc(B(O)O)cc1>>COc1nccc2c1c(-c1ccc(CC#N)cc1)cn2C1CCOC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04659718,CI.O=c1[nH]c2cc(F)ccc2c(=O)o1>>Cn1c(=O)oc(=O)c2ccc(F)cc21,,CC(=O)N(C)C,,[H-].[Na+],,test
US20160220595A1,CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](N)CO.CCOC(=O)C(F)(F)F>>CCCCCCCCCCCCCCCC[C@H](CO)NC(=O)C(F)(F)F,,CCO,,CCN(CC)CC,,test
US20010006969A1,C=CCNc1nc(N)c2scc(C)c2n1.CC(C)(C)N.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=CCNc1nc(NC(=O)NC(C)(C)C)c2scc(C)c2n1,,CC#N,,CCCCCC,CCOC(C)=O,test
US20130338133A1,CCN(CC)S(F)(F)F.Cc1cc(-c2cnc3c(NCC(C)(C)O)cc(-c4ccccc4CO)nn23)ccc1C(=O)NC1CC1>>Cc1cc(-c2cnc3c(NCC(C)(C)O)cc(-c4ccccc4CF)nn23)ccc1C(=O)NC1CC1,,ClCCl,,O,,test
US20080119535A1,CCN(Cc1cn(S(=O)(=O)N(C)C)cn1)c1ccnc(Cl)n1.Oc1ccccc1>>CCN(Cc1cn(S(=O)(=O)N(C)C)cn1)c1ccnc(Oc2ccccc2)n1,,CN(C)C=O,,[H-].[Na+],,test
US20060142333A1,CC1CCc2ccccc2N1.O=[N+]([O-])O>>CC1CCc2ccc([N+](=O)[O-])cc2N1,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20110039824A1,CC(C)OC(=O)C1=CNCC(C)(C)c2c1[nH]c1cc(F)ccc21.O=C(Cl)c1ccc(OCCCN2CCOCC2)cc1>>CC(C)OC(=O)C1=CN(C(=O)c2ccc(OCCCN3CCOCC3)cc2)CC(C)(C)c2c1[nH]c1cc(F)ccc21,,CC#N,,CCN(CC)CC,CO,test
US20130211075A1,CCOC(=O)C1(c2ccc(NC(=O)c3cnn(-c4ccc(C)cc4)c3C)cn2)CCC2(CC1)OCCO2>>CCOC(=O)C1(c2ccc(NC(=O)c3cnn(-c4ccc(C)cc4)c3C)cn2)CCC(=O)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050032786A1,CCOC(=O)CCCCc1cccc(C#N)n1.COC(=O)c1ccccc1S>>CCOC(=O)CCCCc1cccc(-c2nc(=O)c3ccccc3s2)n1,,Cc1ccccc1,,CCN(CC)CC,,test
US04806549,CCCC(=O)c1cnc2c(C)cccc2c1Cl.COc1ccccc1N>>CCCC(=O)c1cnc2ccccc2c1Nc1ccccc1OC,,C1COCCO1,,,,test
US20110092423A1,Cn1nccc1-c1ncc(C(=O)O)s1.N[C@@H](Cc1cccc(F)c1)CN1C(=O)c2ccccc2C1=O>>Cn1nccc1-c1ncc(C(=O)N[C@@H](Cc2cccc(F)c2)CN2C(=O)c3ccccc3C2=O)s1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20090005410A1,CC(C)(C)c1ccc(S(=O)(=O)Cl)cc1.Nc1cc(Cl)cnc1Br>>CC(C)(C)c1ccc(S(=O)(=O)Nc2cc(Cl)cnc2Br)cc1,,c1ccncc1,,,,test
US20050197338A1,N#CCBr.NC(=O)Nc1cn(-c2ccc(-c3cccc(O)c3)c(F)c2)nc1C(N)=O>>N#CCOc1cccc(-c2ccc(-n3cc(NC(N)=O)c(C(N)=O)n3)cc2F)c1,,CC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100256097A1,CCOC(=O)Cn1cc(-c2ccc(Cl)nc2)nn1>>OCCn1cc(-c2ccc(Cl)nc2)nn1,,C1CCOC1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20080207704A1,Cc1c(C(=O)NNC(=O)C(C)(C)C)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1>>Cc1c(-c2nnc(C(C)(C)C)o2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1,,C1CCOC1,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US20090163552A1,CCOC(=O)c1ccc(NC(=O)C(C2CCCCC2)n2c(-c3ccc(Cl)cc3)nc3cc(F)c(F)cc32)cc1.COC(=O)c1ccc(N)c(C(F)(F)F)c1.O=C(NC[C@H]1CC[C@H](C(=O)O)CC1)C(C1CCCCC1)n1c(-c2ccc(Cl)cc2)nc2cc(F)ccc21>>COC(=O)c1ccc(NC(=O)C(C2CCCCC2)n2c(-c3ccc(Cl)cc3)nc3cc(F)c(F)cc32)c(C(F)(F)F)c1,,c1ccncc1,,,,test
US20020133008A1,CCOC(=O)CC(=O)OCC.CCOC(=O)c1cn(Cc2ccc(OC)cc2)nc1N>>CCOC(=O)c1c(O)nc2nn(Cc3ccc(OC)cc3)cc2c1O,,CCO,,C,C[O-].[Na+],test
US20060287291A1,CC(C)(C)OC(=O)N1CC[C@H](Oc2cc([N+](=O)[O-])cc3ccoc23)[C@H](F)C1>>CC(C)(C)OC(=O)N1CC[C@H](Oc2cc(N)cc3ccoc23)[C@H](F)C1,[Ni],C1CCOC1,CCO,NN,O,test
US20160002169A1,COCC(C)(C)c1c(F)cc(NC(=O)[C@H]2c3ccc(OC)cc3CCN2C(=O)OC(C)(C)C)cc1F.Cl>>COCC(C)(C)c1c(F)cc(NC(=O)[C@@H]2NCCc3cc(OC)ccc32)cc1F.Cl,,CCOC(C)=O,,,,test
US05998433,CN(C)Cc1cc2c(o1)CN(C(=O)c1ccc(C(=O)c3ccc(Cl)cc3)cc1)CC2.Cl>>CN(C)Cc1cc2c(o1)CN(C(=O)c1ccc(C(=O)c3ccc(Cl)cc3)cc1)CC2.Cl,,CCOC(C)=O,CO,,,test
US20080132551A1,CCOc1ccc([N+](=O)[O-])c(Nc2cccnc2)c1>>CCOc1ccc(N)c(Nc2cccnc2)c1,[Pd],CO,,,,test
US20160200725A1,CC(C)(C)OC(=O)N1CCN(CCCI)CC1.COc1cc(OC)c(Cl)c(-c2cc3cnc(SC)nc3[nH]c2=O)c1Cl>>COc1cc(OC)c(Cl)c(-c2cc3cnc(SC)nc3n(CCCN3CCN(C(=O)OC(C)(C)C)CC3)c2=O)c1Cl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070054916A1,CN.Nc1ncc2cc(Br)ccc2n1>>CNc1ncc2cc(Br)ccc2n1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20110009354A1,CCOC(C)=NOCCN(C)C[C@H]1O[C@@H](n2c(C)nc3c(N)ncnc32)[C@H](O)[C@@H]1O.CNC[C@H]1O[C@@H](n2c(NC)nc3c(N)ncnc32)[C@H](O)[C@@H]1O>>CCOC(C)=NOCCN(C)C[C@H]1O[C@@H](n2c(NC)nc3c(N)ncnc32)[C@H](O)[C@@H]1O,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20120157509A1,CCCCCCCC(=O)NCCCC[C@H](NC(=O)CCCCCCC)C(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OCc1ccccc1>>CCCCCCCC(=O)NCCCC[C@H](NC(=O)CCCCCCC)C(=O)NCCCC[C@H](N)C(=O)OCc1ccccc1,,C1CCOC1,,CCNCC,,test
US20130190293A1,CC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cn1.Cc1ccc2c(c1)c1c(n2-c2cccc(Br)c2)CCN(C)C1>>CC(=O)Nc1ccc(-c2cccc(-n3c4c(c5cc(C)ccc53)CN(C)CC4)c2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])[O-].[K+].[K+],test
US20040063643A1,BrCCCCCBr.N#CCc1nc2ccccc2[nH]1>>N#CC1(c2nc3ccccc3[nH]2)CCCCC1,,CN(C)C=O,,O,[H-].[Na+],test
US06051210,CC(=O)CNc1c(I)c(NCC(C)=O)c(I)c(C(=O)Cl)c1I.Nc1ccc(CC(=O)O)cc1>>CC(=O)CNc1c(I)c(NCC(C)=O)c(I)c(C(=O)Nc2ccc(CC(=O)O)cc2)c1I,,CC(=O)N(C)C,,,,test
US05489591,CN(C)c1nc(Cl)nc(N2CCOCC2)n1.c1c[nH]cn1>>CN(C)c1nc(N2CCOCC2)nc(-n2ccnc2)n1,,CN(C)C=O,O,ClCCl,[Na+].[OH-],test
US05006520,CCOC(=O)CCl.CN(C)CCNc1ccc(-c2n[nH]c3ncccc23)cc1>>CCOC(=O)Cn1nc(-c2ccc(NCCN(C)C)cc2)c2cccnc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100305113A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=C(NC1(COc2ccc(Br)cc2)COC1)OCc1ccccc1>>CC1(C)OB(c2ccc(OCC3(NC(=O)OCc4ccccc4)COC3)cc2)OC1(C)C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,,CC(=O)[O-].[K+],,test
US20100331326A1,CCOC(=O)c1ccncc1N1CCN(c2ccc3ncsc3c2)C1=O.N>>NC(=O)c1ccncc1N1CCN(c2ccc3ncsc3c2)C1=O,,ClC(Cl)Cl,,CO,,test
US20080200704A1,CCCCCCCC(=O)O.O=S(Br)Br>>CCCCCCCC(=O)Br,,O,,,,test
US20150344466A1,CCOC(=O)c1cc(COC(C)c2ccccc2)on1>>CC(OCc1cc(C(=O)O)no1)c1ccccc1,,O,,CCO,[K+].[OH-],test
US20020028836A1,Cl.Nc1cccc(F)c1.O=C1NCCO1>>Cl.NCCNc1cccc(F)c1,,CCOCC,,CCO,,test
US20130142737A1,CC1CC(O)CC(C)(C)C1.Cc1cc(CCl)c(O)c(-n2nc3ccccc3n2)c1>>Cc1cc(COC2CC(C)CC(C)(C)C2)c(O)c(-n2nc3ccccc3n2)c1,,C1COCCO1,,[H-].[Na+],,test
US20110301122A1,BrCCOCCBr.CCOC(=O)Cc1ccc(Br)cc1>>CCOC(=O)C1(c2ccc(Br)cc2)CCOCC1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20150018363A1,C[Si](C)(C)C#N.Cc1c(CCl)nc2ccc(-n3ccc(OCc4ccc(F)cc4)cc3=O)cn12>>Cc1c(CC#N)nc2ccc(-n3ccc(OCc4ccc(F)cc4)cc3=O)cn12,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150376206A1,COC(=O)c1cccc(Cn2nc(-c3cccc(CCOS(=O)(=O)c4ccc(C)cc4)c3)ccc2=O)c1.Nc1nc2ccccc2[nH]1>>COC(=O)c1cccc(Cn2nc(-c3cccc(CCn4c(N)nc5ccccc54)c3)ccc2=O)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20050277645A1,CN(C)C(=O)CC1Cc2ccccc2C1=O>>CN(C)CCC1Cc2ccccc2C1O,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150344473A1,CC(C)(O)c1ccc(-c2cc3c(-c4ccc(O[C@@H]5CCN(C(=O)CO)C5)c(C#N)c4)ccnc3[nH]2)cc1>>C=C(C)c1ccc(-c2cc3c(-c4ccc(O[C@@H]5CCN(C(=O)CO)C5)c(C#N)c4)ccnc3[nH]2)cc1,,C1CCOC1,,O=C(O)C(F)(F)F,,test
US05189054,CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1N.ClCCl.O=C(Cl)c1ccc(Cl)cc1>>CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1NCC(=O)c1ccc(Cl)cc1,,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US20120245358A1,CCOC(=O)Cc1cn(C2CCCCC2)c(=S)[nH]1>>CCOC(=O)Cc1cn(C2CCCCC2)cn1,,CC(=O)O,,OO,,test
US20030176693A1,Br.CCN(CC)C(=O)c1ccc(C(O)(c2cccc(OC)c2)C2CC2)cc1>>CCN(CC)C(=O)c1ccc(C(=CCCBr)c2cccc(OC)c2)cc1,,CC(=O)O,,O,,test
US20050277640A1,N#Cc1cc(Cc2ccc([N+](=O)[O-])cc2)ccn1>>N#Cc1cc(Cc2ccc(N)cc2)ccn1,[Pd],CCO,,c1ccncc1,,test
US04895862,N#CCc1ccc(O)cc1.OCCc1ccccc1>>N#CCc1ccc(OCCc2ccccc2)cc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090176847A1,CC(=O)OC1CC2CC(N(CC(=O)N3CCCC3C#N)C(=O)OC(C)(C)C)CC2C1.Cl>>CC(=O)OC1CC2CC(NCC(=O)N3CCCC3C#N)CC2C1.Cl,,CCOCC,,,,test
US20050038072A1,CCCS(=O)(=O)Cl.COc1ccc(N)cc1CN1CCC(=O)C(C(c2ccccc2)c2ccccc2)C1>>CCCS(=O)(=O)Nc1ccc(OC)c(CN2CCC(=O)C(C(c3ccccc3)c3ccccc3)C2)c1,,O,,c1ccncc1,,test
US20110207728A1,O=C1c2cc(Br)cn2CC2(c3ccc(CO)cc3)NCCN12.OB(O)c1cccnc1>>O=C1c2cc(-c3cccnc3)cn2CC2(c3ccc(CO)cc3)NCCN12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20160075713A1,CC(C)(C)OC(=O)N1CCC(N)CC1.Cc1ccc(S(=O)(=O)n2ccc3c(Cl)ncnc32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(NC4CCN(C(=O)OC(C)(C)C)CC4)ncnc32)cc1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US04336375,CC(=O)C1CCCCC1=O.NNc1nnn(S)c1N>>Cc1nn(C2=NNN(S)C2N)c2c1CCCC2,,CCO,,Cl,,test
US05532358,COc1nccc(C)c1NC(=O)c1cccnc1NC1CC1>>Cc1ccnc2c1NC(=O)c1cccnc1N2,,c1ccncc1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US04362712,C=O.O=C(O)c1cccc2ccccc12>>C=O.O=C(O)c1cccc2ccccc12,,CC(=O)O,,O=S(=O)(O)O,,test
US20030199440A1,CC(C)(C)OC(=O)CN(CC1CCCC1)S(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1.N=C(N)N>>CC(C)(C)OC(=O)CN(CC1CCCC1)S(=O)(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1,,COCCOC,,Cl,[H-].[Na+],test
US20150031733A1,CC(=O)c1ccc(Br)cc1F.[Br-]>>O=C(CBr)c1ccc(Br)cc1F,,CCOC(C)=O,,,,test
US20100121048A1,CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)C[C@H]1Cc1ccc(C#N)cc1>>N#Cc1ccc(C[C@@H]2CN(Cc3ccccc3)CCN2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120225867A1,C[C@@H](Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1cc(CBr)on1.c1c[nH]cn1>>C[C@@H](Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1cc(Cn2ccnc2)on1,,CC#N,,,,test
US20040132726A1,O=C(Cl)c1ccccc1.O=[N+]([O-])CCO>>O=C(OCC[N+](=O)[O-])c1ccccc1,,c1ccccc1,,,,test
US20060183791A1,CC(C)O.O=[N+]([O-])c1ccc(F)cc1O>>CC(C)Oc1cc(F)ccc1[N+](=O)[O-],,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070123578A1,O=C1CCCCCC1.O=Cc1ccc(F)cc1>>O=C1CCCCCC1=Cc1ccc(F)cc1,,O,,Cl,[K+].[OH-],test
US20090253687A1,Cc1nnc(S)n1N.O=C1COc2ccc(C(=O)C(Br)c3ccccc3)cc2N1>>Cc1nnc2n1N=C(c1ccc3c(c1)NC(=O)CO3)C(c1ccccc1)S2,,CCO,Cc1ccccc1,,,test
US04661438,COc1ccccc1OC.Cl[Te](Cl)(Cl)Cl>>COc1ccc([Te](Cl)(Cl)Cl)cc1OC,,ClC(Cl)Cl,,,,test
US20140228376A1,CC(C)[Si](OS(=O)(=O)C(F)(F)F)(C(C)C)C(C)C.CC(O)(C(=O)NNC(=O)c1nc(Br)c(C(F)(F)F)cc1N)C(F)(F)F>>CC(C)[Si](OC(C)(C(=O)NNC(=O)c1nc(Br)c(C(F)(F)F)cc1N)C(F)(F)F)(C(C)C)C(C)C,,ClCCl,,CCN(CC)CC,,test
US04186132,CCOC(=O)c1ccc2c(c1)C(C)C(=S)N2.O=C1CCC(=O)N1Cl>>CCOC(=O)c1ccc2c(c1)C(C)(Cl)C(=S)N2,,ClCCl,,,,test
US05646308,Cl.N#CCCNC(=O)C1=CC(CF)(CF)Oc2ccc(N)cc21>>Cl.N#CCCNC(=O)C1=CC(CF)(CF)Oc2ccc(N)cc21,,CO,,,,test
US20130157996A1,CC(=O)Oc1ccc(C(=O)N[C@@H](c2ccc(C(F)(F)F)cc2)c2ncccc2F)cc1[N+](=O)[O-]>>CC(=O)Oc1ccc(C(=O)N[C@@H](c2ccc(C(F)(F)F)cc2)c2ncccc2F)cc1N,[Pd],CCOC(C)=O,,,,test
US20120264728A1,CC(O)c1ccnc(Cl)c1.NN>>CC(O)c1ccnc(NN)c1,,CCOCC,CO,O,,test
US20120295897A1,O=C(Cl)C(=O)Cl.O=C(O)c1cccc(CN2C(=O)C3(COc4cc5c(cc43)CCO5)c3ccccc32)c1>>O=C(Cl)c1cccc(CN2C(=O)C3(COc4cc5c(cc43)CCO5)c3ccccc32)c1,,ClCCl,,CN(C)C=O,,test
US20070197604A1,CNC(C)C.Cc1oc(-c2ccc(-c3ccc(S(C)(=O)=O)cc3)cc2)nc1CCO>>Cc1oc(-c2ccc(-c3ccc(S(C)(=O)=O)cc3)cc2)nc1CCN(C)C(C)C,,C1CCOC1,ClCCl,CCN(CC)CC,CS(=O)(=O)Cl,test
US20090208485A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.FC(F)(F)c1cncc(Br)c1>>CC(C)(C)OC(=O)N1CCC(O)(c2cncc(C(F)(F)F)c2)CC1,,ClCCl,,[Li]CCCC,,test
US20110275625A1,CNC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(O)cn2)o1)C1CCCCC1.OCc1ccccn1>>CNC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(OCc3cccnc3)cn2)o1)C1CCCCC1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030225269A1,CC(C)(C)OC(=O)[C@@H]1CCCN2C(=O)CC[C@H](N)C(=O)N12.O=C(Cl)c1ccccc1>>CC(C)(C)OC(=O)[C@@H]1CCCN2C(=O)CC[C@H](NC(=O)c3ccccc3)C(=O)N12,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090124681A1,CCCCCCCCCCC[C@@H](O)C[C@@H]1OC(=O)[C@H]1CC.O=CNCC(=O)O>>CCCCCCCCCCC[C@H](C[C@@H]1OC(=O)[C@H]1CC)OC(=O)CNC=O,,Cc1ccccc1C,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06313126B1,Brc1cc(N2CCNCC2)c2ncccc2c1.Cn1cc(C2CCC(=O)CC2)c2cc(F)ccc21>>Cn1cc([C@@H]2CC[C@H](N3CCN(c4cc(Br)cc5cccnc45)CC3)CC2)c2cc(F)ccc21,,CC(Cl)Cl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20040204386A1,COc1ccc(Cl)cc1-c1nc(Cl)cc(Cl)n1.N>>COc1ccc(Cl)cc1-c1nc(N)cc(Cl)n1,,C1CCOC1,,,,test
US20150299125A1,CC(C)(C)OC(=O)NCCCCCCO.O=C(Cl)OCCl>>CC(C)(C)OC(=O)NCCCCCCOC(=O)OCCl,,ClCCl,,c1ccncc1,,test
US04064347,Cl.ClC(Cl)Cl.O=C(CCCN1CCCCC1)c1ccc2c(c1)C(=O)c1cc(C(=O)CCCN3CCCCC3)ccc1-2>>Cl.Cl.O=C(CCCN1CCCCC1)c1ccc2c(c1)C(=O)c1cc(C(=O)CCCN3CCCCC3)ccc1-2,,ClC(Cl)Cl,,,,test
US06005103,C1CCNCC1.O=c1oc(-c2ccccc2)cc(O)c1SSc1c(O)cc(-c2ccccc2)oc1=O.SC1CCCC1>>O=c1oc(-c2ccccc2)cc(O)c1C(CC1CC1)SC1CCCC1,,CC(=O)O,,CCO,,test
US20160200686A1,COc1ccc(C(C)(C)C(NC(=O)OC(C)(C)C)C(=O)Nc2ccccc2N)cc1>>COc1ccc(C(C)(C)C(NC(=O)OC(C)(C)C)c2nc3ccccc3[nH]2)cc1,,CC(=O)O,,N#N,,test
US20070082912A1,CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(S(C)(=O)=O)ccc2O)c1.Fc1ccc(CBr)cc1>>CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(S(C)(=O)=O)ccc2OCc2ccc(F)cc2)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US05296492,CC1(C)C=C(n2cc(CO[Si](C)(C)C(C)(C)C)ccc2=O)c2cc(C#N)ccc2O1>>CC1(C)C=C(n2cc(CO)ccc2=O)c2cc(C#N)ccc2O1,,C1COCCO1,CO,Cl,O,test
US05578627,CC(C)(C)OC(=O)Nc1ccc2onc(OCC(COC(N)=O)NC(=O)OC(C)(C)C)c2c1.Cl>>Cl.NC(=O)OCC(N)COc1noc2ccc(N)cc12,,CO,,C1COCCO1,,test
US20100227866A1,NC(=O)N[N+](=O)[O-].NC1CCCCC1N1C(=O)c2ccccc2C(C(=O)NOCc2ccccc2)C1c1ccc(Cl)cc1Cl>>NC(=O)NC1CCCCC1N1C(=O)c2ccccc2C(C(=O)NOCc2ccccc2)C1c1ccc(Cl)cc1Cl,,CCO,,,,test
US20060194816A1,COS(=O)(=O)OC.O=C(c1ccc(Cl)cc1Cl)C1Oc2cc(Br)ccc2C1=O>>COc1c(C(=O)c2ccc(Cl)cc2Cl)oc2cc(Br)ccc12,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130017194A1,CO.O=C(O)Cc1cccnc1Cl>>COC(=O)Cc1cccnc1Cl,,CO,,CC(=O)Cl,,test
US20140349991A1,C=CCOc1ccc2c(=O)c(C)c(C3CCN(C(=O)CC)CC3)oc2c1.O=C1CCC(=O)N1Br>>CCC(=O)N1CCC(c2oc3c(Br)c(O)ccc3c(=O)c2C)CC1,,CN(C)C=O,,O,,test
US20030078251A1,CC(=O)Cl.COc1cccc([C@H]2O[C@H](CC(=O)NCCCCCC(=O)O)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC>>COc1cccc([C@H]2O[C@H](CC(=O)NCCCCCC(=O)O)C(=O)N(CC(C)(C)COC(C)=O)c3ccc(Cl)cc32)c1OC,,O,,CCOC(C)=O,c1ccncc1,test
US05439917,CSc1cc2c(C)c(C)nc-2n(CC(=O)c2ccccc2)c1.O=C(OO)c1cccc(Cl)c1>>Cc1nc2n(CC(=O)c3ccccc3)cc(S(C)=O)cc-2c1C,,ClCCl,,,,test
US20130190316A1,CCOC(=O)Cn1nccc1-c1ncccc1CCl.COc1cc(C=O)c(O)cn1>>CCOC(=O)Cn1nccc1-c1ncccc1COc1cnc(OC)cc1C=O,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20140213586A1,COc1cc(N)ccn1.O=C(c1c[nH]c2ccccc12)C(Cl)c1ccccc1>>O=C(c1c[nH]c2ccccc12)C(Nc1ccnc(O)c1)c1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US05360811,C#CCCCCCCCCCC.O=Cc1nc(Br)cs1>>CCCCCCCCCCC#Cc1csc(C=O)n1,,C1CCOC1,,CCN(CC)CC,,test
US04198425,CC(=O)CC(CCc1ccccc1)OC(C)=O.CCOC(=O)CBr>>CCOC(=O)CC(C)(O)CC(CCc1ccccc1)OC(C)=O,[Zn],,,,,test
US04066773,CCOC(=O)C1CCCCN1.COc1ccc2cc(S(=O)(=O)N[C@@H](CCCNC(=N)N)C(=O)Cl)ccc2c1>>CCOC(=O)C1CCCCN1C(=O)[C@H](CCCNC(=N)N)NS(=O)(=O)c1ccc2cc(OC)ccc2c1,,ClC(Cl)Cl,,CCN(CC)CC,N#N,test
US20090186879A1,CCC(CC)c1ccc(Cl)c2nc3n(c12)CCCCN3c1ncc([N+](=O)[O-])cc1C>>CCC(CC)c1ccc(Cl)c2nc3n(c12)CCCCN3c1ncc(N)cc1C,[Pd],C1CCOC1,,,,test
US20130165476A1,CCOC(=O)Cl.COC(=O)[C@H](c1ccccc1Cl)N1CCC2SC(=O)C=C2C1>>CCOC(=O)Oc1cc2c(s1)CCN([C@H](C(=O)OC)c1ccccc1Cl)C2,,C1CCOC1,,CCN(CC)CC,CCOC(C)=O,test
US20090227622A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2cc([N+](=O)[O-])cc(C(F)(F)F)c2)CC1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2cc(N)cc(C(F)(F)F)c2)CC1,[Pd],CO,,,,test
US04160036,CC(=O)CC(C)=O.Fc1ccccc1CCl>>CC(=O)CCc1ccccc1F,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20120202785A1,N#Cc1c(F)ccc([N+](=O)[O-])c1Nc1cncc(F)c1>>N#Cc1c(F)ccc(N)c1Nc1cncc(F)c1,[Fe],CO,O,[Cl-].[NH4+],,test
US06060508,CC(=O)C(C)Cl.Oc1ccccc1Br>>CC(=O)C(C)Oc1ccccc1Br,,CN(C)C=O,O,[I-].[K+],,test
US05679696,BrC1CCCC1.CSc1ccc(Br)cc1O>>CSc1ccc(Br)cc1OC1CCCC1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100075942A1,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Clc1cccnc1Cl>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(-c2ncccc2Cl)cc1,,COCCOC,,O=C([O-])O.[Na+],,test
US04377584,C1=COCCC1.C[C@]12CCCC=C1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12>>C[C@]12CCCC=C1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](OC3CCCCO3)CC[C@@H]12,,CCOCC,,Cc1ccc(S(=O)(=O)Cl)cc1,,test
US06066638,CCCI.O=c1c2cc(I)cc(I)c2[nH]c(=S)n1CC1CCCO1>>CCCSc1nc2c(I)cc(I)cc2c(=O)n1CC1CCCO1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110312935A1,O=C(Nc1ccccc1)c1ccc([N+](=O)[O-])c([N+](=O)[O-])c1>>Nc1ccc(C(=O)Nc2ccccc2)cc1N,[Pd],C1CCOC1,,[H][H],,test
US20080227787A1,CCBr.O=C(NN=C(C=NO)c1cccc(Cl)c1)c1ccccc1>>CCON=CC(=NNC(=O)c1ccccc1)c1cccc(Cl)c1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20030078251A1,CCOC(=O)C(F)(F)Oc1cccc(NC(=O)C[C@H]2O[C@@H](c3cccc(C)c3C)c3cc(Cl)ccc3N(CC(C)(C)COC(C)=O)C2=O)c1>>CCC(C)C[C@@H]1O[C@H](CC(=O)Nc2cccc(OC(F)(F)C(=O)O)c2)C(=O)N(CC(C)(C)CO)c2ccc(Cl)cc21,,O,,CCO,[Na+].[OH-],test
US05162354,O=C1NCC(CBr)O1.O=c1n(Cl)c(=O)n(Cl)c(=O)n1Cl>>O=C1OC(CBr)CN1Cl,,ClCCl,,,,test
US06380197B1,CCCNCCC.COC(=O)c1ccc(CBr)cc1>>CCCN(C=C1C=CC(C(=O)OC)=CC1)CCC,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090076063A1,COC(=O)CC(=O)OC.Cn1ccc(=O)oc1=O>>COC(=O)c1c(O)ccn(C)c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20120010228A1,CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(CCCC(=O)c4ccccc4)CC3)C2=O)c1>>CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(CCCC(O)c4ccccc4)CC3)C2=O)c1,,CCO,,[BH4-].[Na+],,test
US06294537B1,CC(=O)NC1(c2ccccc2)CCN(Cc2ccccc2)CC1>>CCNC1(c2ccccc2)CCN(Cc2ccccc2)CC1,,C1CCOC1,O,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20130281444A1,COC(=O)Cl.N#Cc1ccc(NC(=O)c2cc(-c3ccc(F)cc3F)ccc2O)cc1>>N#Cc1ccc(-n2c(=O)oc3ccc(-c4ccc(F)cc4F)cc3c2=O)cc1,,C1CCOC1,c1ccncc1,Cl,,test
US20090093497A1,CC(C)(C)OC(=O)N1CC[C@H](Nc2ccc([N+](=O)[O-])cn2)C1>>CC(C)(C)OC(=O)N1CC[C@H](Nc2ccc(N)cn2)C1,[Pd],CO,,,,test
US20150361070A1,CC(C)(C)OC(=O)c1c(CBr)cccc1[N+](=O)[O-].C[N+]1([O-])CCOCC1>>CC(C)(C)OC(=O)c1c(C=O)cccc1[N+](=O)[O-],,CC#N,,,,test
US06077859,BrC(Br)(Br)Br.N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)cc1C1CC(=O)C1>>N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)cc1C1CC(=C(Br)Br)C1,,ClCCl,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05631373,NCC(=O)[O-].O=[N+]([O-])c1cc(F)c(Cl)cc1F.[Na+]>>O=C([O-])CNc1cc(Cl)c(F)cc1[N+](=O)[O-].[Na+],,CCO,O,,,test
US20080146606A1,CC(C)(C)c1cc2ccc[n+]([O-])c2[nH]1.CS(=O)(=O)Cl>>CC(C)(C)c1cc2c(Cl)ccnc2[nH]1,,CN(C)C=O,,[Na+].[OH-],,test
US20090209571A1,COC(=O)Cc1ccccc1Br.OB(O)c1cc2ccccc2s1>>COC(=O)Cc1ccccc1-c1cc2ccccc2s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,[Cs+].[F-],,test
US20060122263A1,NCCc1ccc(F)cc1.c1ccc(C(c2ccccc2)[C@@H]2C[C@H]3O[C@H]3CO2)cc1>>O[C@@H]1C[C@@H](C(c2ccccc2)c2ccccc2)OC[C@H]1NCCc1ccc(F)cc1,,CCO,,,,test
US20120252801A1,CCNC[C@H](C)O.O=CC=O>>CCN1CC(=O)O[C@@H](C)C1,,Cc1ccccc1,,,,test
US20120129872A1,COc1ccc(S(N)(=O)=O)cc1N.S=C(Cl)Cl>>COc1ccc(S(N)(=O)=O)cc1N=C=S,,ClC(Cl)Cl,O,CCOC(C)=O,O=C([O-])O.[Na+],test
US20040176435A1,N#Cc1cc2c(F)ccc(O)c2s1.O[C@@H](CCI)c1ccccc1>>N#Cc1cc2c(F)ccc(O[C@H](CCI)c3ccccc3)c2s1,,C1CCOC1,,,,test
US20100261755A1,CCOC(=O)CC(=O)[C@H]1CCN(C(=O)OC)[C@@H](Cc2cc(F)c(F)c(F)c2)C1.NO>>COC(=O)N1CC[C@H](c2cc(=O)[nH]o2)C[C@@H]1Cc1cc(F)c(F)c(F)c1,,CO,O,Cl,[Na+].[OH-],test
US20120022054A1,CNCc1ccccc1OC.S=C1CCCO1>>COc1ccccc1CN(C)C(=O)CCCS,,Cc1ccccc1,,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US20140057902A1,COC(=O)CC1c2ccc(F)c(Br)c2CCN1C(=O)CNC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCC(=O)N1CCc2c(ccc(F)c2Br)C1CC(=O)O,,CCO,,[Na+].[OH-],,test
US20030087874A1,CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NCCC=O.COc1ccc(Cn2c(=O)ccn([C@@H]3O[C@H]([C@H](O)[C@H](N)C(=O)OC(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]3O[Si](C)(C)C(C)(C)C)c2=O)cc1>>COc1ccc(Cn2c(=O)ccn([C@@H]3OC([C@H](O)[C@H](NCCCNC(=O)[C@H](CC(C)C)NC(=O)OCc4ccccc4)C(=O)OC(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]3O[Si](C)(C)C(C)(C)C)c2=O)cc1,CC(=O)O,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20120196864A1,CCN1C(=N)/C(=C/c2ccc(O)c(OC)c2)NC1=O.Cc1ccc(S(=O)(=O)Cl)cc1>>CCN1C(=N)/C(=C/c2ccc(OS(=O)(=O)c3ccc(C)cc3)c(OC)c2)NC1=O,,c1ccncc1,,[Cl-].[NH4+],,test
US20100076026A1,COC(=O)COc1ccc(N=C=O)c(F)c1.Clc1ccc(-n2nc3ccccc3c2NC2CCCCC2)cc1>>COC(=O)COc1ccc(NC(=O)N(c2c3ccccc3nn2-c2ccc(Cl)cc2)C2CCCCC2)c(F)c1,,ClCCCl,,CCN(CC)CC,,test
US05179125,CC(=O)SCC(Cc1ccc(N(C)C)cc1)C(=O)Nc1cc(C)cc(C(=O)O)c1.Cl>>Cc1cc(NC(=O)C(CS)Cc2ccc(N(C)C)cc2)cc(C(=O)O)c1.Cl,,CO,,Cl,[Na+].[OH-],test
US03933829,Clc1ccc2c(Cl)ccnc2c1.Nc1ccc(S(=O)(=O)O)c(Cl)c1>>O=S(=O)(O)c1ccc(Nc2ccnc3cc(Cl)ccc23)cc1Cl,,O,,Cl,,test
US20060004084A1,N#Cc1ccc2c(c1)COC2=O.O=C1Cc2ccccc2N1>>N#Cc1ccc2c(c1)COC2=C1C(=O)Nc2ccccc21,,C1CCOC1,O,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US05118686,CCCN.CCCOc1ccccc1-c1nc(O)cc(Cl)n1>>CCCNc1cc(=O)[nH]c(-c2ccccc2OCCC)n1,,CCO,,,,test
US20060264425A1,C1CSCCN1.C[Si](C)(C)N=C=O>>NC(=O)N1CCSCC1,,CC(C)O,,,,test
US04808605,CN(C[C@@H]1CC[C@@H](c2nc3ccccc3[nH]2)CC1)C(=O)OCc1ccccc1>>CNC[C@@H]1CC[C@@H](c2nc3ccccc3[nH]2)CC1,[Pd],CCO,,,,test
US20150336935A1,C[C@@H]1[C@H](N)C[C@H]2C(C)(C)CCC[C@]2(C)[C@H]1C(=O)c1cc(O)cc(O)c1.O=Cc1ccc[nH]1>>C[C@@H]1[C@H](NCc2ccc[nH]2)C[C@H]2C(C)(C)CCC[C@]2(C)[C@H]1C(=O)c1cc(O)cc(O)c1,,C1CCOC1,CCOC(C)=O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160039780A1,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.COC12CCC(C=O)(CC1)CC2>>COC(=O)/C=C/C12CCC(OC)(CC1)CC2,,C1CCOC1,,,,test
US20140155398A1,COC(=O)Nc1nccc2c1ccn2C(=O)OCc1ccccc1>>COC(=O)Nc1nccc2[nH]ccc12,[Pd],CCO,,,,test
US20020016329A1,CCn1cnc2c(Nc3ccc(N)cc3)nc(N[C@@H]3CC[C@@H](O)CC3)nc21.COC(=O)Cl>>CCn1cnc2c(Nc3ccc(NC(=O)OC)cc3)nc(N[C@@H]3CC[C@@H](O)CC3)nc21,,ClCCl,,,,test
US20080248419A1,BrCc1ccccc1.Br[Mg]c1ccc(-c2ccccc2)cc1.S=C=S>>S=C(SCc1ccccc1)c1ccc(-c2ccccc2)cc1,,C1CCOC1,,,,test
US20080045554A1,CCCCCn1c2nc[nH]c2c(=O)n2c(CCN)nnc12.O=C1CCC(=O)N1Br>>CCCCCn1c2nc(Br)[nH]c2c(=O)n2c(CCN)nnc12,,C1CCOC1,,,,test
US20140038941A1,CC(C)(C)O.CC(C)(C)c1nc2cc(C(=O)O)ccn2c1CC1CCCCC1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)Nc1ccn2c(CC3CCCCC3)c(C(C)(C)C)nc2c1,,Cc1ccccc1,O,CCN(CC)CC,,test
US20130274244A1,Cc1cccc(Cn2ncc3c(N)cccc32)n1.O=C1CCC(=O)N1Cl>>Cc1cccc(Cn2ncc3c(N)ccc(Cl)c32)n1,,C1CCOC1,O,O=S(=O)(O)O,O=C([O-])[O-].[Na+].[Na+],test
US20030069261A1,CC(C)(C)OC(=O)NCC1CCC(NC(=O)c2cccc3ccccc23)CC1>>NCC1CCC(NC(=O)c2cccc3ccccc23)CC1,,C1COCCO1,ClCCl,Cl,,test
US20160272655A1,CCc1nc(C)ccc1OCC(=O)OC.O=C(OO)c1cccc(Cl)c1>>CCc1c(OCC(=O)OC)ccc(C)[n+]1[O-],,ClCCl,,,,test
US20020052498A1,CCCCCCCCCCCCCCN=C=O.CN1CCN(C(=O)CCc2ccccc2O)CC1>>CCCCCCCCCCCCCCNC(=O)Oc1ccccc1CCC(=O)N1CCN(C)CC1,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,,test
US20110306612A1,COC(=O)c1cccc(NC(=O)c2cnccn2)c1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>COC(=O)c1cccc(NC(=O)c2cnccn2)c1N,,CO,,Cl,,test
US20110015175A1,ClCCCI.O=C(O)Cc1ccc(F)cc1>>O=C(O)C(CCCCl)c1ccc(F)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US04242278,CC1(C)C(Br)C(=O)C1CC(Br)(Br)Br.O>>CC1(C)[C@H](C=C(Br)Br)[C@@H]1C(=O)O,,O,,C1COCCO1,[Na+].[OH-],test
US04415572,COC=CC(=O)Nc1ccc(N2CCN(C(=O)c3ccc(OC)c(OC)c3)CC2)cc1>>COc1ccc(C(=O)N2CCN(c3ccc4[nH]c(=O)ccc4c3)CC2)cc1OC,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20080255105A1,Cc1ccc(NC(=O)OC(C)(C)C)cc1-c1ccc(C(=O)O)cc1.Nc1ccc(CN2CCS(=O)(=O)CC2)cc1>>Cc1ccc(NC(=O)OC(C)(C)C)cc1-c1ccc(C(=O)Nc2ccc(CN3CCS(=O)(=O)CC3)cc2)cc1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040063735A1,COC(=O)C(N)CN1CCc2[nH]ncc2C1.O=C(c1ncc[nH]1)c1ncc[nH]1.O=C1Nc2ccccc2CN1C1CCNCC1>>COC(=O)C(CN1CCc2[nH]ncc2C1)NC(=O)N1CCC(N2Cc3ccccc3NC2=O)CC1,,ClCCl,,,,test
US04622322,CC(=O)SCCN1C(=O)c2ccccc2C1=O.O=C(CBr)c1ccc(F)cc1>>O=C(CSCCN1C(=O)c2ccccc2C1=O)c1ccc(F)cc1,,CCO,,C[O-].[Na+],,test
US20060004052A1,CC(C)(C)OC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)O.Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O>>CC(C)(C)OC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O,,CN(C)C=O,ClCCl,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090118509A1,CC(=O)CCC(=O)c1ccccc1.NNC(=O)c1ccncc1>>Cc1ccc(-c2ccccc2)n1NC(=O)c1ccncc1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20160002228A1,CC(C)n1nc(I)cc1C1CCN(C2COC2)CC1.CC1(C)OB(c2cnc(N)c(C(F)(F)F)c2)OC1(C)C>>CC(C)n1nc(-c2cnc(N)c(C(F)(F)F)c2)cc1C1CCN(C2COC2)CC1,,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05958954,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2ccc(C(C)C)cc2)=CC(C)(C)O3)cc1>>CC(C)c1ccc(C2=CC(C)(C)Oc3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20090069250A1,CC(C)(C)OC(=O)c1ccc(CBr)cc1.CCOC(=O)CN(C)C>>CCOC(=O)C(C)(c1ccc(C(=O)OC(C)(C)C)cc1)N(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20080287396A1,C=CCBr.COc1c(N2C[C@@H]3[C@@H](CCCN3C(=O)OC(C)(C)C)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12>>C=CCOC(=O)c1cn(C2CC2)c2c(OC)c(N3C[C@@H]4[C@@H](CCCN4C(=O)OC(C)(C)C)C3)c(F)cc2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060229363A1,COC(=O)c1cc(S(=O)(=O)NCCBr)cc(C)c1C.Oc1ccc(OC(F)(F)F)cc1>>COC(=O)c1cc(S(=O)(=O)NCCOc2ccc(OC(F)(F)F)cc2)cc(C)c1C,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090270389A1,CSc1ncc2c(O)cc(=O)n(C3CCCC3)c2n1.O=P(Br)(Br)Br>>CSc1ncc2c(Br)cc(=O)n(C3CCCC3)c2n1,,CC(Cl)Cl,,,,test
US20060258666A1,CC1(C)CC=C(c2cc(Cc3nnn[nH]3)ccc2NC(=O)c2nc(C#N)cn2COCC[Si](C)(C)C)CC1.CN(C)CCCl>>CN(C)CCn1nnc(Cc2ccc(NC(=O)c3nc(C#N)cn3COCC[Si](C)(C)C)c(C3=CCC(C)(C)CC3)c2)n1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,Cl,test
US20110098481A1,CO.Cc1cccc([C@@H](C)C(=O)O)c1>>COC(=O)[C@H](C)c1cccc(C)c1,,CO,,O=S(=O)(O)O,O=C([O-])[O-].[Na+].[Na+],test
US20120010191A1,CN(C)CCOc1ccc([N+](=O)[O-])nc1>>CN(C)CCOc1ccc(N)nc1,[Pd],CO,,,,test
US20130281465A1,CC1(C)OB(c2ccnn2C2CCCCO2)OC1(C)C.Fc1ccc(Br)nc1>>Fc1ccc(-c2ccnn2C2CCCCO2)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20120129811A1,COc1ccncc1N.Cn1cnc2c(N=C=S)cccc21>>COc1ccncc1NC(=S)Nc1cccc2c1ncn2C,,CN(C)C=O,,,,test
US05849757,CCOC(=O)C(C(=O)O)C1CN(C(=O)OCc2ccccc2)C1>>C=C(C(=O)OCC)C1CN(C(=O)OCc2ccccc2)C1,,CC#N,,CC(=O)[O-].[K+],,test
US20040171881A1,CCCCBr.COC(=O)c1cc(I)c2c(c1)NC(=O)CO2>>CCCCN1C(=O)COc2c(I)cc(C(=O)OC)cc21,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US03931153,Nc1ccc(C(=O)O)c([N+](=O)[O-])c1.O=C(Cl)C1CC1>>O=C(O)c1ccc(NC(=O)C2CC2)cc1[N+](=O)[O-],,C1CCOC1,O,[Na+].[OH-],,test
US05231107,CON=CC1=CCCNC1.Cc1ccc(OC(=O)Cl)cc1>>CON=CC1=CCCN(C(=O)Oc2ccc(C)cc2)C1,,ClCCl,,CCN(CC)CC,,test
US20100048636A1,CCC[C@](OCCN=[N+]=[N-])(c1cccc(Cl)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1>>CCC[C@](OCCN)(c1cccc(Cl)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150045339A1,C#Cc1cccc(N)c1.CC(C)(C)OC(=O)NCC=O>>C#Cc1cccc(NCCNC(=O)OC(C)(C)C)c1,CC(=O)O,CCOC(C)=O,ClCCl,O=C([O-])O.[Na+],,test
US20070225292A1,COC(=O)Cl.Nc1ccc(C(=O)Nc2cccnc2C(=O)NCC2CCOCC2)c2ccccc12>>COC(=O)Nc1ccc(C(=O)Nc2cccnc2C(=O)NCC2CCOCC2)c2ccccc12,CN(C)c1ccncc1,CC#N,,,,test
US04613603,Clc1ncc(-c2ccccc2Cl)nn1.OC1CCNCC1>>OC1CCN(c2ncc(-c3ccccc3Cl)nn2)CC1,,CCO,,,,test
US20140315888A1,CN(C(=O)OC(C)(C)C)C1CN(c2nc3ncc(Br)cc3n3nnnc23)C1>>CNC1CN(c2nc3ncc(Br)cc3n3nnnc23)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040087601A1,CCCCN.CCCC[C@H](NC(=O)OC(C)(C)C)C(=O)O>>CCCCNC(=O)[C@H](CCCC)NC(=O)OC(C)(C)C,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20070197604A1,CS(=O)(=O)c1ccc(B(O)O)cc1.Cc1oc(-c2ccc(Br)cc2)nc1CCN1CCCCC1>>Cc1oc(-c2ccc(-c3ccc(S(C)(=O)=O)cc3)cc2)nc1CCN1CCCCC1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20150065482A1,CCOC(=O)c1nn(-c2cccc(Br)c2)c2c1CNCC2.CS(=O)(=O)Cl>>CCOC(=O)c1nn(-c2cccc(Br)c2)c2c1CN(S(C)(=O)=O)CC2,,ClCCl,,CCN(CC)CC,,test
US05196570,CCCCCCCCC(/C=C/C=C/c1ccccc1CCCCC(=O)O)OC(C)=O>>CCCCCCCCC(O)/C=C/C=C/c1ccccc1CCCCC(=O)O,,CO,,O=S(=O)(O)O,[Na+].[OH-],test
US20140349990A1,CCOC(=O)c1c(I)c(C)nn1-c1cnc(OC)nc1OC.O=Cc1ccc(Cl)cc1>>CCOC(=O)c1c(C(O)c2ccc(Cl)cc2)c(C)nn1-c1cnc(OC)nc1OC,,CCCCCC,CCOC(C)=O,,,test
US03971819,NS(=O)(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1Cl.Sc1ccccc1>>NS(=O)(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1Sc1ccccc1,,O=C([O-])O,[Na+],,,test
US05200550,C=CCO.O=C(O)c1ccc(O)cc1C(F)(F)F>>C=CCOC(=O)c1ccc(O)cc1C(F)(F)F,,O=S(=O)(O)O,,,,test
US05102667,C=COC(=O)Cl.O=C1CCC(c2cccc(F)c2)(c2cccc(F)c2)C2CN(Cc3ccccc3)CC12>>C=COC(=O)N1CC2C(=O)CCC(c3cccc(F)c3)(c3cccc(F)c3)C2C1,,ClCCCl,,,,test
US20080275213A1,CC(C)(C)OC(=O)n1cc(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)NCc2ccccc2)c2ccccc21>>CC(C)(C)OC(=O)n1cc(C[C@H](N)C(=O)NCc2ccccc2)c2ccccc21,,CN(C)C=O,,C1CCNCC1,,test
US20100076203A1,CCOC(=O)C(CC(=O)OC1CC(C)CCC1C(C)C)(NC(=O)OCc1ccccc1)C(N)=O>>CCOC(=O)[C@](CC(=O)OC1CC(C)CCC1C(C)C)(NC(=O)OCc1ccccc1)C(N)=O,,CC(C)=O,,,,test
US20110245224A1,C[C@@H]1CN(c2c(C=O)cc3c(C(=O)N4CC(F)(F)C4)noc3c2F)C[C@@H](C)O1.O=C1CC(=O)NC(=O)N1>>C[C@@H]1CN2c3c(cc4c(C(=O)N5CC(F)(F)C5)noc4c3F)CC3(C(=O)NC(=O)NC3=O)[C@H]2[C@H](C)O1,,CCO,,,,test
US20150018422A1,COc1ccc(F)c(-c2ccc(OCc3cccc(CCCO)c3)cc2CC(C)(C)C)c1>>COc1ccc(F)c(-c2ccc(OCc3cccc(CCC=O)c3)cc2CC(C)(C)C)c1,,CS(C)=O,,CCN(CC)CC,Cl,test
US05158947,BrCCCCCBr.O=C1NCCOc2ccccc21>>O=C1c2ccccc2OCCN1CCCCCBr,,CN(C)C=O,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20040014940A1,CC(C)C(Cl)OC(=O)Cl.CC(C)CC(CN)CC(=O)OCc1ccccc1>>CC(C)CC(CNC(=O)OC(Cl)C(C)C)CC(=O)OCc1ccccc1,,ClCCl,,CN1CCOCC1,Cl,test
US20140200197A1,CC(C)(C)C(=O)Nc1cncc(F)c1.II>>CC(C)(C)C(=O)Nc1cncc(F)c1I,,C1CCOC1,,CN(C)CCN(C)C,[Li]CCCC,test
US20130079306A1,CCOC(=O)c1snc(-c2ccc(Cl)cc2Cl)c1N>>CCOC(=O)c1cc(-c2ccc(Cl)cc2Cl)ns1,,C1CCOC1,,CC(C)CCON=O,,test
US20160130226A1,CC(=O)Nc1ccc(Br)c(F)c1>>Nc1ccc(Br)c(F)c1,,CCO,,Cl,,test
US20080171776A1,Cc1cccc(-c2nc(CI)c(C)o2)c1.Cc1cccc(COCCCO)c1C(=O)OC(C)(C)C>>Cc1cccc(-c2nc(COCCCOCc3cccc(C)c3C(=O)O)c(C)o2)c1,,COC(C)(C)C,,O,[H-].[Na+],test
US20060148858A1,CCOC(=O)CCc1ccc(O)c(OCC)c1.CCOc1nn(-c2cc(C(F)(F)F)ccn2)cc1CCCO>>CCOc1nn(-c2cc(C(F)(F)F)ccn2)cc1CCCOc1ccc(CCC(=O)O)cc1OC,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20150191419A1,Cl.O=C(CCC(=O)OCCCCCC(=O)OCc1ccccc1)CNC(=O)OCc1ccccc1>>Cl.NCC(=O)CCC(=O)OCCCCCC(=O)O,[Pd],CC(C)O,,[H][H],,test
US20070037794A1,CNc1c(C(=O)O)cccc1[N+](=O)[O-]>>CNc1c(N)cccc1C(=O)O,[Pd],CCO,CCOC(C)=O,[H][H],,test
US06410539B1,COC(=O)c1cc(CN=[N+]=[N-])ccc1Cc1ccc(F)cc1>>COC(=O)c1cc(CN)ccc1Cc1ccc(F)cc1,[Pd],CO,,Cl,,test
US20050119137A1,CCCCCCCCCCCCCCCC(=O)[O-].CCCCO>>CCCCCCCCCCCCCCCC(=O)OCCCC,,O,,Cc1ccccc1,,test
US20080293770A1,O=[N+]([O-])O.Oc1cc(F)ccc1Cl>>O=[N+]([O-])c1cc(Cl)c(O)cc1F,,ClCCl,,,,test
US20050209249A1,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)N1CCSC1>>CC(C)(C)OC(=O)N1CC(=O)C[C@H]1C(=O)N1CCSC1,,CS(C)=O,,CCN(CC)CC,,test
US20090005410A1,COC(=O)c1nnn(-c2cc(Cl)ccc2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1C>>Cc1c(C(=O)O)nnn1-c1cc(Cl)ccc1NS(=O)(=O)c1ccc(C(C)(C)C)cc1,,C1CCOC1,,[Na+].[OH-],,test
US20040132801A1,CC1CCC(C(C)C)C(OC(=O)C2CC(=Cc3cccc(F)c3)CN2C(=O)OC(C)(C)C)C1>>CC1CCC(C(C)C)C(OC(=O)C2CC(Cc3cccc(F)c3)CN2C(=O)OC(C)(C)C)C1,,CCOC(C)=O,Cc1ccccc1,,,test
US20050203091A1,C[Si](C)(C)CCOCn1nc(I)c2cnc(Oc3ccc(F)cc3F)nc21>>Fc1ccc(Oc2ncc3c(I)n[nH]c3n2)c(F)c1,,CO,,Cl,,test
US20110195954A1,O=C(O)c1cc(N2CCC(N3CCc4ccccc4NC3=O)CC2)ncn1.O=C1CC2CNc3cccc(c32)N1>>O=C1CC2CN(C(=O)c3cc(N4CCC(N5CCc6ccccc6NC5=O)CC4)ncn3)c3cccc(c32)N1,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,test
US08329682B2,Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCCCC1)CCC2.O=C1Cc2cc(F)ccc2N1>>Cc1c(/C=C2\C(=O)Nc3ccc(F)cc32)[nH]c2c1C(=O)N(CCN1CCCCC1)CCC2,,CCO,,C1CCNCC1,,test
US04535183,Cc1cc2c(O)cccc2o1.N#Cc1ccc(CBr)cc1>>Cc1cc2c(OCc3ccc(C#N)cc3)cccc2o1,,CCO,,[I-].[K+],O=C([O-])O.[Na+],test
US05698575,COc1ccc2c(=O)c(I)coc2c1.c1cn[nH]c1>>COc1ccc2c(=O)cc(-c3cc[nH]n3)oc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030220341A1,CC(C)(C)OC(=O)NCCCCN.CC(C)(C)OC(=O)n1cnc2c1C(=O)CCC2>>CC(C)(C)OC(=O)NCCCCNC1CCCc2ncn(C(=O)OC(C)(C)C)c21,,ClCCl,,O=C([O-])O.[Na+],,test
US20130324528A1,CC(C)(C)OC(=O)N1CCC(CBr)CC1.Ic1ccnc2cn[nH]c12>>CC(C)(C)OC(=O)N1CCC(Cn2cc3nccc(I)c3n2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20110319378A1,C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@H](c2ccc(Cl)cc2)OC1=O.CC(C)[C@H](N)CO>>C=CC[C@@](C)(C[C@H](c1cccc(Cl)c1)[C@@H](O)c1ccc(Cl)cc1)C(=O)N[C@H](CO)C(C)C,,CCOC(C)=O,,,,test
US04720495,CC1CNCCN1.CCOC(=O)c1cn2c3c(c(Cl)c(Cl)cc3c1=O)C(=O)CC2C>>CCOC(=O)c1cn2c3c(c(N4CCNC(C)C4)c(Cl)cc3c1=O)C(=O)CC2C,,CC#N,,,,test
US20020147343A1,CC(C)(C)OC(=O)N1CC[C@H](Sc2cc(-c3ccc[nH]3)c3c4c(ccc(F)c24)NC3=O)C1>>O=C1Nc2ccc(F)c3c(S[C@H]4CCNC4)cc(-c4ccc[nH]4)c1c23,,ClCCl,O=C(O)C(F)(F)F,O,,test
US20120238582A1,BrCCCBr.CCOC(=O)Cc1ccc([N+](=O)[O-])cc1>>CCOC(=O)C1(c2ccc([N+](=O)[O-])cc2)CCC1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20080139548A1,CCOC(=O)c1cc2cc(Cl)ccc2n1CC#N>>N#CCn1c(C(=O)O)cc2cc(Cl)ccc21,,C1CCOC1,O,[Li]O,,test
US20050250729A1,CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1.ClCCNCCCl>>CC(=O)Nc1ccc(S(=O)(=O)N(CCCl)CCCl)cc1,,C1COCCO1,,CCN(CC)CC,Cl,test
US20030171413A1,CN(C)c1ccncc1.NC1CCN(Cc2ccccc2)CC1.O=C(O)Cc1cccc2occc12>>O=C(Cc1cccc2cocc12)NC1CCN(Cc2ccccc2)CC1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20100144729A1,CCCc1c(OC)ccc2cc(C(=O)Nc3ccc(C4CCCN4C(=O)OC(C)(C)C)cc3)c(=O)oc12>>CCCc1c(OC)ccc2cc(C(=O)Nc3ccc(C4CCCN4)cc3)c(=O)oc12,,ClCCl,,Cl,,test
US20160272621A1,CC(=O)c1ccncc1NC(=O)c1ccnc(Nc2ccc(C(F)(F)F)cn2)c1>>CC(O)c1ccncc1NC(=O)c1ccnc(Nc2ccc(C(F)(F)F)cn2)c1,,CO,,[BH4-].[Na+],,test
US20150133432A1,Cc1nn(C2CCCCO2)c2nc(-c3ccc(OCc4ccccc4)cc3F)cc(C(=O)N3CCN(Cc4ccccc4)CC3(C)C)c12>>Cc1nn(C2CCCCO2)c2nc(-c3ccc(OCc4ccccc4)cc3F)cc(CN3CCN(Cc4ccccc4)CC3(C)C)c12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04146721,CCOC(=O)CC(C(=O)c1ccccc1)C(=O)c1ccccc1.NNc1ccccc1Cl>>O=C(O)Cc1c(-c2ccccc2)nn(-c2ccccc2Cl)c1-c1ccccc1,,CC(=O)O,,Cl,CC(=O)[O-].[Na+],test
US04436660,C1=Cc2ccccc2Nc2ccccc21.N#CCl>>N#CN1c2ccccc2C=Cc2ccccc21,,ClCCCl,,CC(=O)N(C)C,,test
US05739116,CCOC(=O)CCCOc1ccc(C=O)cc1OC>>COc1cc(C=O)ccc1OCCCC(=O)O,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20060135447A1,CI.Oc1cccc2nccnc12>>COc1cccc2nccnc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060019958A1,O=[N+]([O-])c1cccc(-n2nc(C(F)(F)F)cc2-c2ccccc2)c1>>Nc1cccc(-n2nc(C(F)(F)F)cc2-c2ccccc2)c1,[Pd],CCO,,CC(=O)O,,test
US20160083354A1,COC(=O)c1ccc(CBr)cc1.Nc1cccc(C(F)(F)F)n1>>COC(=O)c1ccc(CNc2cccc(C(F)(F)F)n2)cc1,,CC#N,,CCN(C(C)C)C(C)C,O,test
US20050065340A1,BrCCCCBr.COc1cc(-c2nc3ccccc3o2)ccc1CC#N>>COc1cc(-c2nc3ccccc3o2)ccc1C1(C#N)CCCC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20160272633A1,C=C(c1ccc(Br)cc1)C(F)(F)F.COCN(Cc1ccccc1)C[Si](C)(C)C>>FC(F)(F)C1(c2ccc(Br)cc2)CCN(Cc2ccccc2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US08129371B2,N#CCCn1ncc2c(N3CC4CCC(C3)O4)nc(Cl)nc21.Nc1ccc(B(O)O)cc1>>N#CCCn1ncc2c(N3CC4CCC(C3)O4)nc(-c3ccc(N)cc3)nc21,,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20100249099A1,COc1cccc2c1nc(C(F)F)n2-c1nc(C2=CN(C(=O)OC(C)(C)C)CCC2)nc(N2CCOCC2)n1>>COc1cccc2c1nc(C(F)F)n2-c1nc(C2CCCN(C(=O)OC(C)(C)C)C2)nc(N2CCOCC2)n1,[Pd],C1CCOC1,CO,,,test
US05962002,C=CC(C)(C)C1=C(O)C(=O)c2ccccc2C1=O.CON>>C=CC(C)(C)C1(O)CC(=O)c2ccccc2C1=NOC,,c1ccncc1,,CCOCC,Cl,test
US20140315833A1,C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43C)[C@@H]1CCC2=O.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]43C)[C@@H]1CCC2=O.O=C(O)[C@H](O)[C@@H](O)C(=O)O,,CCCCCCC,,C1CCOC1,,test
US04885373,CCOCCBr.NC1CCc2cc3c(cc2C1)OCC3>>CCOCCNC1CCc2cc3c(cc2C1)OCC3,,CCO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20100130739A1,Cc1nc(OCC(=O)N(C)C2CCN(CC3CC3)CC2)nc(C)c1NC(=O)OC(C)(C)C>>Cc1nc(OCC(=O)N(C)C2CCN(CC3CC3)CC2)nc(C)c1N,,ClC(Cl)Cl,,Cl,[Na+].[OH-],test
US06316477B1,COC=Nc1cc(-c2ncon2)nn1-c1c(Cl)cc(C(F)(F)F)cc1Cl>>Nc1cc(-c2ncon2)nn1-c1c(Cl)cc(C(F)(F)F)cc1Cl,,CC(C)=O,O,O=S(=O)(O)O,,test
US04367232,CC1CN(CC2CCCCC2)CCC1N.COc1cc(N)c(Cl)cc1C(=O)O>>COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCCCC2)CC1C,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US05328927,CC(=O)NC(Cc1csc2ccccc12)C(=O)CCc1cc(C(F)(F)F)cc(C(F)(F)F)c1.NO>>CC(=O)NC(Cc1csc2ccccc12)C(CCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)=NO,,CO,,Cl,CC(=O)[O-].[Na+],test
US20090281160A1,CCOC(=O)CCC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)CCC(=O)O,,C1CCOC1,CO,CC(=O)O,[Li+].[OH-],test
US05840991,COc1cc(C=O)cc(OC)c1OC>>COc1cc(CO)cc(OC)c1OC,,C1CCOC1,,O,[BH4-].[Na+],test
US20100022550A1,CC(C)C(=O)N[C@@H]1CCc2c(c3cc(C#N)ccc3n2Cc2cccc(F)c2)C1.O=CO>>CC(C)C(=O)N[C@@H]1CCc2c(c3cc(C=O)ccc3n2Cc2cccc(F)c2)C1,,CO,O,,,test
US20100035936A1,COc1cccc2c1CCC(=O)C2.NCc1ccccc1>>COc1cccc2c1CCC(NCc1ccccc1)C2,,ClCCl,O,CC(=O)O,O=C([O-])O.[Na+],test
US20020010182A1,Cc1ccc(C[C@@H]2CNCCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C.Cl.ClCC#Cc1cccnc1>>Cc1ccc(C[C@@H]2CN(CC#Cc3cccnc3)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C.Cl.Cl,,CN(C)C=O,O,[I-].[K+],,test
US20050250769A1,Cc1c(C(=O)NC2CCCCC2)cc(-c2cc(Cl)ccc2F)n1CC1CCCN1C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>Cc1c(C(=O)NC2CCCCC2)cc(-c2cc(Cl)ccc2F)n1CC1CCCN1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US05593993,COc1ccccc1CCN.S=C(n1ccnc1)n1ccnc1>>COc1ccccc1CCNC(=S)n1ccnc1,,CC#N,,,,test
US20010051731A1,CCOC(=O)c1csc(N)n1.O=C(Nc1ccc(C(CC2CCCC2)C(=O)O)cc1)c1cccnc1>>CCOC(=O)c1csc(NC(=O)C(CC2CCCC2)c2ccc(NC(=O)c3cccnc3)cc2)n1,CN(C)C=O,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20100029643A1,CS(N)(=O)=O.FC(F)(F)c1ccc(Cl)nc1>>CS(=O)(=O)Nc1ccc(C(F)(F)F)cn1,,CS(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20120010191A1,C1COCCN1.Nc1ccc(C(=O)O)cn1>>Nc1ccc(C(=O)N2CCOCC2)cn1,,CCO,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20020040040A1,Cc1ccccc1-c1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ncc1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1ccccc1-c1cc(N2CCNCC2)ncc1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1,,CCOC(C)=O,,CO,[Na+].[OH-],test
US20120165318A1,COC(=O)c1ccc2nc(-c3cccc(F)c3)c(N(C)C(C)C)nc2c1>>O=C(O)c1ccc2nccnc2c1,,O,,CO,[Na+].[OH-],test
US05154918,O=C(O)CCC(=O)NCCS>>O=C1CCC(=O)N1CCS,,Cc1ccccc1C,,O,,test
US20120283238A1,CC(C)C=O.CNC1CCC(Nc2ncnc3sc4c(c23)CCC4)CC1>>CC(C)CN(C)C1CCC(Nc2ncnc3sc4c(c23)CCC4)CC1,,CCOC(C)=O,CO,[BH3-]C#N.[Na+],,test
US05244908,NCCCCSc1cccc2nccn12.O=S(=O)(Cl)c1cccc2ccccc12>>O=S(=O)(NCCCCSc1cccc2nccn12)c1cccc2ccccc12,,ClCCl,,CCN(CC)CC,,test
US20080292626A1,CC(=O)n1c(Br)cc2cc3c(=O)n(Cc4cccs4)c(C(Br)C(C)C)nc3cc21.CC(C)(C)OC(=O)NCCCN>>CC(C)C(NCCCNC(=O)OC(C)(C)C)c1nc2cc3[nH]c(Br)cc3cc2c(=O)n1Cc1cccs1,,ClCCl,,,,test
US04070362,CCCCNc1c(C(=O)OCC)c(C)nc(NCC(C)C)c1[N+](=O)[O-]>>CCCCNc1c(N)c(NCC(C)C)nc(C)c1C(=O)OCC,[Pd],CCCCO,,[H][H],,test
US20090264428A1,CC#N.CC(C)(C)OC(=O)N[C@H]1CCNC1.COCCCCC(O)[C@@H]1CCCN(C(=C[N+](=O)[O-])SC)C1.COCCCCC(O)[C@@H]1CCCNC1.CSC(=C[N+](=O)[O-])SC>>COCCCC[C@@](O)(c1ccccc1Oc1ccccc1C)[C@@H]1CCCN(C(=C[N+](=O)[O-])N2CC[C@H](NC(=O)OC(C)(C)C)C2)C1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20090170908A1,CC#C[C@@H](CC(=O)OC)c1ccc(OCC2=C[C@]3(CCC2)CC[C@@H](O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C3)cc1>>CC#C[C@@H](CC(=O)OC)c1ccc(OCC2=C[C@]3(CCC2)CC[C@@H](O)C3)cc1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20110144105A1,CC(=O)c1ccc(B(O)O)cc1.COc1cnc2c(c1)cc(C(=CC1CCCC1)OS(=O)(=O)c1ccc(C)cc1)n2S(=O)(=O)c1ccccc1>>COc1cnc2c(c1)cc(C(=CC1CCCC1)c1ccc(C(C)=O)cc1)n2S(=O)(=O)c1ccccc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US05639778,CCCN(CC1CCC1)C1CCc2c(ccc3[nH]ccc23)C1.O=C1CCC(=O)N1Cl>>CCCN(CC1CCC1)C1CCc2c(ccc3[nH]cc(Cl)c23)C1,,C1CCOC1,,,,test
US20070219186A1,COCCN(Cc1ccc(C(=O)OC)cc1C(F)(F)F)C(=O)OC(C)(C)C>>COCCN(Cc1ccc(C(=O)O)cc1C(F)(F)F)C(=O)OC(C)(C)C,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20060264438A1,CCOC(=O)[C@H]1CN(C(=O)OC(C)(C)C)CC[C@H]1N[C@H](C)c1ccccc1>>CCOC(=O)[C@H]1CN(C(=O)OC(C)(C)C)CC[C@H]1N,[Pd],CCO,,O=C[O-].[NH4+],,test
US05773530,CC(C)(C)[Si](C)(C)OC1CCCC(n2nc(-c3c(-c4ccccc4)nn4ccccc34)ccc2=O)C1>>O=c1ccc(-c2c(-c3ccccc3)nn3ccccc23)nn1C1CCCC(O)C1,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140378475A1,COc1ccc(Cn2ccc(=O)n(-c3cccc(Br)c3C)c2=O)cc1>>Cc1c(Br)cccc1-n1c(=O)cc[nH]c1=O,,O=C(O)C(F)(F)F,,O=S(=O)(O)C(F)(F)F,,test
US20050090499A1,CC(C)(C)c1ccc(C(=O)Cl)cc1.Nc1cccc(-c2cn3ccnc3c(Nc3ccccc3)n2)c1>>CC(C)(C)c1ccc(C(=O)Nc2cccc(-c3cn4ccnc4c(Nc4ccccc4)n3)c2)cc1,,CN(C)C=O,Cc1ccccc1,CCN(CC)CC,,test
US20100249099A1,C1CCNCC1.C=CS(=O)(=O)N1CCN(c2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4c(OC)cccc43)n2)CC1>>COc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCN(S(=O)(=O)CCN3CCCCC3)CC2)n1,,C1CCOC1,,C1COCCO1,,test
US06376490B1,COB(OC)OC.COc1nc2cc(Cl)c(Cl)cc2nc1OC>>COc1nc2cc(Cl)c(Cl)c(B(O)O)c2nc1OC,,C1CCOC1,O,Cl,CC(C)[N-]C(C)C.[Li+],test
US20080015187A1,CCOC(=O)c1nn2c(c1OCc1ccccc1)C(=O)N(C)CC2c1csc(C)n1>>CCOC(=O)c1nn2c(c1O)C(=O)N(C)CC2c1csc(C)n1,,ClCCl,,BrB(Br)Br,,test
US05393732,BrBr.OCC#Cc1ncn(C(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>BrCC#Cc1ncn(C(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,ClCCl,,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150087646A1,C#Cc1ccc(-n2nc(-c3c(F)cccc3Cl)[nH]c2=O)cc1.Ic1cnc(N2CCOCC2)nc1>>O=c1[nH]c(-c2c(F)cccc2Cl)nn1-c1ccc(C#Cc2cnc(N3CCOCC3)nc2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CS(C)=O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04082764,COC(C)([O-])[O-].Nc1ccccc1C(=O)c1ccccc1Cl>>COC(C)=Nc1ccccc1C(=O)c1ccccc1Cl,,c1ccccc1,,CC(=O)O,,test
US20150038438A1,COc1ccc(Cn2c3c(c(O)c(C(=O)O)c2=O)CCc2cc4c(cc2-3)cc(CO)n4C)c(OC)c1>>COc1ccc(Cn2c3c(c(O)c(C(=O)O)c2=O)CCc2cc4c(cc2-3)cc(C=O)n4C)c(OC)c1,O=[Mn]=O,ClCCl,,,,test
US20150060731A1,CCCC1CCC(C2CCC(C(F)(F)Oc3cc(F)c(O)c(F)c3)CC2)CC1.FC(F)(F)/C=C/Cl>>CCCC1CCC(C2CCC(C(F)(F)Oc3cc(F)c(O/C=C/C(F)(F)F)c(F)c3)CC2)CC1,,CN1CCCC1=O,,O,[H-].[Na+],test
US20110111046A1,CO.O=C(O)c1ccnc(Br)c1>>COC(=O)c1ccnc(Br)c1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20070254866A1,CC(C)I.CCOC(=O)c1cn(C2CC2)c2c(O)c(F)c(F)cc2c1=O>>CCOC(=O)c1cn(C2CC2)c2c(OC(C)C)c(F)c(F)cc2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110257137A1,CC(C)(C)OC(=O)N1CCNCC1.N#Cc1ccc2nc(Cl)c(Cl)nc2c1>>CC(C)(C)OC(=O)N1CCN(c2nc3ccc(C#N)cc3nc2Cl)CC1,,CCO,,O,,test
US20120252805A1,COc1cccc(-c2c(C)sc3nc(OC)cc(N)c23)c1.O=S(=O)(Cl)c1cccc(Cl)c1>>COc1cccc(-c2c(C)sc3nc(OC)cc(NS(=O)(=O)c4cccc(Cl)c4)c23)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20090149457A1,CCOC(=O)n1nc(N)c2cc(C(=O)OC(C)(C)C)sc21.O=C(Cl)c1ccccc1[N+](=O)[O-]>>CCOC(=O)n1nc(NC(=O)c2ccccc2[N+](=O)[O-])c2cc(C(=O)OC(C)(C)C)sc21,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20060276533A1,COC(=O)c1sc(C2=CCC3(CC2)OCCO3)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)[C@@H]1CC[C@@H](O)CC1>>COC(=O)c1sc(C2CCC3(CC2)OCCO3)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)[C@@H]1CC[C@@H](O)CC1,,CO,,,,test
US20120232283A1,COc1ccc(CN)cc1OC.O=C(Cl)c1ccccc1>>COc1ccc(CNC(=O)c2ccccc2)cc1OC,,C1CCOC1,,CCN(CC)CC,,test
US20110152318A1,CC(NC(=O)c1coc(Cl)n1)c1cc(F)c(NS(C)(=O)=O)c(F)c1.OB(O)c1ccccc1Cl>>CC(NC(=O)c1coc(-c2ccccc2Cl)n1)c1cc(F)c(NS(C)(=O)=O)c(F)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140171403A1,CC(C)(C)OC(=O)NC1CCN(C(=O)OCc2cc(Cl)cc(C#N)c2)CC1>>N#Cc1cc(Cl)cc(COC(=O)N2CCC(N)CC2)c1,,C1COCCO1,CCOC(C)=O,Cl,,test
US20070185079A1,COc1ccc2c(C)cc(N(C(=O)OCc3ccccc3)[C@H]3CCC[C@H](NC(=O)OCc4ccccc4)C3)nc2c1>>COc1ccc2c(C)cc(N[C@H]3CCC[C@H](N)C3)nc2c1,[Pd],CCO,,,,test
US20120101083A1,Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(C(=O)CBr)CC2.NC(CO)CO>>Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(C(=O)CNC(CO)CO)CC2,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100087431A1,O=C1c2ccccc2C(=O)N1CCn1cc(CI)nn1>>Cc1cn(CCN2C(=O)c3ccccc3C2=O)nn1,[Pd],CCO,,,,test
US20120323002A1,C1COCCN1.Nc1nnc(Cl)cc1Br.O=C(CBr)c1ccc(N2CCCC2)cc1>>Clc1cc(N2CCOCC2)c2nc(-c3ccc(N4CCCC4)cc3)cn2n1,,CCO,,,,test
US20030199550A1,CN(CC[C@@H]1CC[C@@H](/C=C/CO)CC1)C(=O)OC(C)(C)C.Cl>>CNCC[C@@H]1CC[C@@H](/C=C/CO)CC1.Cl,,C1COCCO1,,,,test
US20110152237A1,CCOC(=O)[C@@H]1CC2(CCC(F)(F)CC2)CN1.COC(=O)N[C@H](C(=O)O)C(C)C>>COC(=O)N[C@H](C(=O)N1CC2(CCC(F)(F)CC2)C[C@H]1C(=O)O)C(C)C,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100016319A1,C1COCCN1.CCC(C)(C)c1cc(NC(=O)NCc2ccccc2Oc2ccnc(Cl)n2)n(-c2ccc(C)cc2)n1>>CCC(C)(C)c1cc(NC(=O)NCc2ccccc2Oc2ccnc(N3CCOCC3)n2)n(-c2ccc(C)cc2)n1,,CCO,,,,test
US20080261920A1,CC(C)(C)OC(=O)N1[C@@H](C(C)(Cc2ccccc2)OC(=S)Oc2ccccc2)COC1(C)C>>CC(=Cc1ccccc1)[C@H]1COC(C)(C)N1C(=O)OC(C)(C)C,,Cc1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US06093838,CCCCN(c1ccc(C(=O)OCC)cc1)c1ccc2c(c1)C(C)(C)OC2(C)C>>CCCCN(c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)OC2(C)C,,CCO,,[Na+].[OH-],,test
US05225572,CCc1ccccc1.[Al+3].[Cl-].[Cl-].[Cl-].c1ccccc1>>C=C.CCc1ccccc1.[Al+3].[Cl-].[Cl-].[Cl-],,c1ccccc1,,,,test
US20090156612A1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.O=C(OCc1ccccc1)N1CCN[C@H](CO)C1>>O=C(OCc1ccccc1)N1CCN(C(c2ccccc2)(c2ccccc2)c2ccccc2)[C@H](CO)C1,,CN(C)C=O,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20130053366A1,CCN(CC)S(F)(F)F.Cc1ccc2c(c1)c1c(n2CC(C)(O)c2cccnc2)CCN(C)C1>>Cc1ccc2c(c1)c1c(n2CC(C)(F)c2cccnc2)CCN(C)C1,,ClCCl,,,,test
US20060258838A1,COC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@H](N)Cc1c[nH]c2ccccc12.O=C(N[C@H](C(=O)O)c1ccccc1)OCc1ccccc1>>COC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)OCc1ccccc1)c1ccccc1,,C1CCOC1,,On1nnc2ccccc21,,test
US04412077,CC(=O)O.CCC(=O)c1cc(C#N)c(=O)[nH]c1CC.O=S(=O)(O)O>>CCC(=O)c1cc(C(=O)O)c(=O)[nH]c1CC,,CC(=O)O,,O,,test
US20020099055A1,CC(C)CC=O.O=C(O)c1ccoc1>>CC(C)CC(O)c1occc1C(=O)O,,C1CCOC1,O,Cl,CC(C)[N-]C(C)C.[Li+],test
US20150087825A1,CCOC(=O)CC(=O)c1cc(Br)ccc1F.OCCO>>CCOC(=O)CC1(c2cc(Br)ccc2F)OCCO1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120142685A1,Clc1cc(-c2cc3cnccc3c(Cl)n2)ccn1.NC(=O)C1CCNCC1>>NC(=O)C1CCN(c2nc(-c3ccnc(Cl)c3)cc3cnccc23)CC1,,CCO,,CCN(CC)CC,,test
US20050267149A1,COC(=O)c1ccccc1COc1ccc(CCN)cc1.O=S(=O)(Cl)Cc1ccccc1>>COC(=O)c1ccccc1COc1ccc(CCNS(=O)(=O)Cc2ccccc2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20100113441A1,CC(CNC(=O)OC(C)(C)C)Nc1nc(-c2ccc(Cl)cc2Cl)cc2nccn12.O=C(O)C(F)(F)F>>CC(CN)Nc1nc(-c2ccc(Cl)cc2Cl)cc2nccn12.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20140045819A1,O=C1CCC(=O)N1Cl.O=C1CCc2cc(Br)ccc2N1>>O=C1CCc2cc(Br)cc(Cl)c2N1,,CN(C)C=O,,,,test
US20130078392A1,C[C@H]1CCC[C@@H](C)N1.Cl[SiH2]Cl>>CC1CCCC(C)N1[SiH2]Cl,,C1CCOC1,,[Li]CCCC,,test
US20050137201A1,CCOC(=O)n1ccc2ccc(Cl)nc21>>Clc1ccc2cc[nH]c2n1,,CO,,[Na+].[OH-],,test
US20040053908A1,COc1cc2nccc(Cl)c2cc1C(=O)Cl.N>>COc1cc2nccc(Cl)c2cc1C(N)=O,,C1CCOC1,,O,O,test
US03933844,CCOC(=O)c1cc(=O)c2c(C)c(Cl)c(C)cc2o1.N>>Cc1cc2oc(C(N)=O)cc(=O)c2c(C)c1Cl,,CCO,,,,test
US20110118245A1,COc1cc2ncnc(Cl)c2cc1OCc1ccccc1.Nc1cccc(O)c1>>COc1cc2ncnc(Oc3cccc(N)c3)c2cc1OCc1ccccc1,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05648534,BrC1Cc2ccccc2C1Br.O=S(=O)(O)O>>c1ccc2c(c1)C[C@H]1O[C@@H]21,,CC#N,,,,test
US20080161344A1,CC(C)(C)c1ccc(Oc2cccc(C=O)c2)cc1.COc1cc2c(cc1OC)CNCC2>>COc1cc2c(cc1OC)CN(Cc1cccc(Oc3ccc(C(C)(C)C)cc3)c1)CC2,,CC(=O)O,ClCCCl,[Na+].[OH-],,test
US20030153568A1,CCNC(=O)Nc1nc2ccc(Br)c(O)c2s1.Fc1ccc(CBr)cc1>>CCNC(=O)Nc1nc2ccc(Br)c(OCc3ccc(F)cc3)c2s1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080176926A1,Cc1cc(C=O)cc(C)c1C=CC(=O)O>>Cc1cc(CO)cc(C)c1CCC(=O)O,[Pd],CCO,,CCN(C(C)C)C(C)C,,test
US20080139631A1,Fc1cc(F)cc(-c2nc(CCl)no2)c1.N#Cc1ccc2[nH]c(CCC(F)(F)F)cc2c1C(F)(F)F>>N#Cc1ccc2c(cc(CCC(F)(F)F)n2Cc2noc(-c3cc(F)cc(F)c3)n2)c1C(F)(F)F,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090186870A1,O=C(O)c1ccc([N+](=O)[O-])cc1Cl.O=[N+]([O-])O>>O=C(O)c1cc([N+](=O)[O-])c([N+](=O)[O-])cc1Cl,,O=S(=O)(O)O,,,,test
US20120022060A1,COc1ccccc1N=C=O.Cl.Clc1cnc2[nH]c3c(c2c1)CNCC3>>COc1ccccc1NC(=O)N1CCc2[nH]c3ncc(Cl)cc3c2C1.Cl,,CCOCC,ClCCl,CCN(C(C)C)C(C)C,,test
US06348485B1,CN(C)C=O.c1ccc2c(c1)CCO2>>O=Cc1ccc2c(c1)CCO2,,O,,O=P(Cl)(Cl)Cl,,test
US20030212271A1,CCOC(=O)C(=CN(C)c1ccc(CN2CCOCC2)cc1)C(=O)OCC.O=C(O)C(F)(F)F>>CCOC(=O)c1cn(C)c2c(F)cccc2c1=O,,Cc1ccccc1,,O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3,,test
US20040092582A1,COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(O)c1)=NC(C)(C)C2.NC(=O)CBr>>COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(OCC(N)=O)c1)=NC(C)(C)C2,,CN(C)C=O,,O,CC(C)(C)[O-].[K+],test
US04589905,CCOC(=O)c1cnn(C(C)(C)C)c1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1cnn(C(C)(C)C)c1CBr,,ClC(Cl)(Cl)Cl,,,,test
US05089496,O=C(OO)c1cccc(Cl)c1.O=C1c2ccc(Cl)cc2CCc2cccnc21>>O=C1c2ccc(Cl)cc2CCc2ccc[n+]([O-])c21,,ClCCl,,,,test
US20120245161A1,COC(=O)/C=C/c1cccc2[nH]ccc12>>COC(=O)CCc1cccc2[nH]ccc12,[Pd],CCOC(C)=O,,[H][H],,test
US20140206699A1,COc1ccc(CCN2CCN(c3nc(Br)ns3)CC2)cc1.FC1(F)CCNCC1>>COc1ccc(CCN2CCN(c3nc(N4CCC(F)(F)CC4)ns3)CC2)cc1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,Cl,test
US20040186160A1,CN(C)CCCc1c(C=O)[nH]c2c1CCCCC2.COc1ccc2c(c1)NC(=O)C2>>COc1ccc2c(c1)NC(=O)/C2=C\c1[nH]c2c(c1CCCN(C)C)CCCCC2,,CCO,,C1CCNCC1,,test
US20050176701A1,C[Si](C)(C)C=[N+]=[N-].Cl.O=C(Cl)C1CCCC1>>O=C(CCl)C1CCCC1,,C1CCOC1,,C1COCCO1,,test
US05380724,CC(C)(C)OC(=O)N1CCN(CC(O)COc2ccc(CC#N)cc2)CC1.Nc1nc(N)c(N=O)c(N)n1>>CC(C)(C)OC(=O)N1CCN(CC(O)COc2ccc(-c3nc4c(N)nc(N)nc4nc3N)cc2)CC1,,CCOCCO,,[Na],,test
US05436240,CN(C)C1CNc2c(cc(Br)cc2[N+](=O)[O-])C1>>CN(C)C1CNc2c(N)cccc2C1,[Pd],CCO,,,,test
US20040192653A1,CI.COc1ccc(CN(Cc2cc(F)ccc2Oc2ccc3c(cnn3C)c2)C(=O)Nc2cc(C(C)(C)C)nn2-c2ccc(C)cc2)cc1>>COc1ccc(CN(Cc2cc(F)ccc2Oc2ccc3c(cnn3C)c2)C(=O)N(C)c2cc(C(C)(C)C)nn2-c2ccc(C)cc2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20110190334A1,Nc1c(Nc2ccc(I)cc2F)cc(=O)n2c1SCC2.O=S(=O)(Cl)C1CC1>>O=c1cc(Nc2ccc(I)cc2F)c(NS(=O)(=O)C2CC2)c2n1CCS2,,c1ccncc1,,,,test
US20160256458A1,CC(=O)N1c2ccc(-c3cnn(C4CC4)c3)cc2N(c2nn(C3CCCCO3)c3ccccc23)C[C@@H]1C>>CC(=O)N1c2ccc(-c3cnn(C4CC4)c3)cc2N(c2n[nH]c3ccccc23)C[C@@H]1C,,ClCCl,,O=C(O)C(F)(F)F,,test
US05700936,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.Nc1nc(O)c2ncn(COC(CO)CO)c2n1>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.Nc1nc(O)c2ncn(COC(CO)CO)c2n1,,CN(C)C=O,,CCN(CC)CC,O,test
US20050043545A1,CC(=O)[C@@H]1C[C@@](CC(C)C)(C(=O)OC(C)(C)C)N(C(=O)c2ccc(C(C)(C)C)cc2)[C@H]1c1nccs1.COC(OC)N(C)C.NO>>CC(C)C[C@@]1(C(=O)O)C[C@@H](c2ccno2)[C@H](c2nccs2)N1C(=O)c1ccc(C(C)(C)C)cc1,,CCO,,Cl,,test
US20140235620A1,CC(C)[C@H]1COC(=O)N1c1ccnc(F)n1.C[C@H](N)c1ccc(CO)cc1>>CC(C)[C@H]1COC(=O)N1c1ccnc(N[C@@H](C)c2ccc(CO)cc2)n1,,CCOC(C)=O,CS(C)=O,CCN(C(C)C)C(C)C,Cl,test
US06093732,CS(=O)(=O)Cl.O=C(NCc1ccc(Cl)cc1)c1cnc2c(F)cc(CCCO)cc2c1O>>CS(=O)(=O)OCCCc1cc(F)c2ncc(C(=O)NCc3ccc(Cl)cc3)c(O)c2c1,CN(C)c1ccncc1,CN(C)C=O,ClCCl,CCN(CC)CC,,test
US07803800B2,CC(C)(C)OC(=O)C=Cc1ccc(C=CC(=O)c2cccnc2)c(F)c1>>O=C(O)C=Cc1ccc(C=CC(=O)c2cccnc2)c(F)c1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100240702A1,C=C(C)n1c(=O)n(CC(=O)c2ccccc2F)c2ccccc21.NO>>C=C(C)n1c(=O)n(CC(=NO)c2ccccc2F)c2ccccc21,,CCO,,Cl,c1ccncc1,test
US05852045,Cc1ccc(S(=O)(=O)Cl)cc1.NC(=O)C[C@H](N)C(=O)O>>Cc1ccc(S(=O)(=O)N[C@@H](CC(N)=O)C(=O)O)cc1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20050043323A1,CCOC(=O)C(CN)c1ccccc1.CCOC(=O)CC(=O)Cl>>CCOC(=O)CC(=O)NCC(C(=O)OCC)c1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
US20100069499A1,C#CCOc1c(F)cc(C(=O)O)cc1Cl.O=S(Cl)Cl>>C#CCOc1c(F)cc(C(=O)Cl)cc1Cl,,CN(C)C=O,,Cc1ccccc1,,test
US20110305729A1,CCOC(=O)CCCCCCN(c1ccccn1)c1cc(-c2ccc(C)cc2)ccn1.NO>>Cc1ccc(-c2ccnc(N(CCCCCCC(=O)NO)c3ccccn3)c2)cc1,,CN(C)C=O,CO,,,test
US20140005164A1,COC(=O)[C@@H]1CC[C@@H](Cn2c(=O)n(C)c3ccc(OCc4ccc(OC)cc4)cc32)CC1>>COc1ccc(COc2ccc3c(c2)n(C[C@@H]2CC[C@@H](C(=O)O)CC2)c(=O)n3C)cc1,,C1CCOC1,,O,[Li+].[OH-],test
US20160152570A1,CCOC(=O)[C@H](Cc1ccc(OCc2cc(OC)ccn2)cc1)OCC.CNOC>>CCO[C@@H](Cc1ccc(OCc2cc(OC)ccn2)cc1)C(=O)N(C)OC,,C1CCOC1,,Cl,,test
US20040039001A1,Cc1ccc(S(=O)(=O)[O-])cc1.NC(=[NH2+])Nc1nc(-c2ccccc2[N+](=O)[O-])c2cc(Cl)ccc2n1>>Cc1ccc(S(=O)(=O)[O-])cc1.NC(=[NH2+])Nc1nc(-c2ccccc2N)c2cc(Cl)ccc2n1,[Ni],CO,,,,test
US20090318456A1,Nc1nc(S)nc(O)c1N.O=CC(=NO)c1ccc(F)cc1>>Oc1nc(S)nc2ncc(-c3ccc(F)cc3)nc12,,CO,,Cl,,test
US04086417,CCCCCCCCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCCCCCCCC.Nc1nc(=O)n([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)cc1F>>CCCCCCCCCCCCCCCCCC(=O)Nc1nc(=O)n([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)cc1F,,O,,C1COCCO1,,test
US20110183974A1,N#Cc1ccc2cc(Cl)ccc2n1.NO>>NC(=NO)c1ccc2cc(Cl)ccc2n1,,CCO,O,Cl,O=C([O-])O.[Na+],test
US20080076758A1,CN(CC1CCCN1C(=O)OC(C)(C)C)S(C)(=O)=O>>CN(CC1CCCN1)S(C)(=O)=O,,CCOCC,ClCCl,Cl,,test
US20150197527A1,CCCCCCCCCCCCn1c2ccccc2c2nc(SCC(=O)OC(C)(C)C)n(-c3ccccc3)c(=O)c21>>CCCCCCCCCCCCn1c2ccccc2c2nc(SCC(=O)O)n(-c3ccccc3)c(=O)c21,,CC#N,,O=C(O)C(F)(F)F,,test
US20090093483A1,CCOC(=O)C(C(=O)OCC)C(=O)C(C)(C)c1ccccc1>>CCOC(=O)C1=C(O)c2ccccc2C(C)(C)C1=O,,CCOC(C)=O,,O=S(=O)(O)O,,test
US20110263571A1,Cc1cnc(N2CCN(C(=O)OC(C)(C)C)CC2)c(Cl)c1.O=C(Cl)c1ccc(Br)cc1F>>Cc1cnc(N2CCN(C(=O)c3ccc(Br)cc3F)CC2)c(Cl)c1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20140309207A1,CI.O=C(Nc1ncc(Cl)s1)N1CC2(CCNC2)c2cc(Br)ccc21>>CN1CCC2(C1)CN(C(=O)Nc1ncc(Cl)s1)c1ccc(Br)cc12,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130281449A1,CCOC(=O)C(=[N+]=[N-])/C(=C\C(=O)OC)C(F)F>>CCOC(=O)c1nnc(OC)cc1C(F)F,,CCOCC,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060014631A1,CCCCOC(=O)C(Cl)CC(Cl)(Cl)Cl>>CCCCOC(=O)C=CC(Cl)(Cl)Cl,,Cc1ccccc1,,C1CCC2=NCCCN2CC1,O,test
US05872138,BrCc1ccc(OC(C2CCCCC2)C2CCCCC2)cc1.Nc1ccncc1>>Nc1cc[n+](Cc2ccc(OC(C3CCCCC3)C3CCCCC3)cc2)cc1.[Br-],,CC#N,,,,test
US04753932,Cc1ccccc1CCl.[Mg]>>Cc1ccccc1CCl.[Mg],,CCOCC,CCOCC,,,test
US20060257987A1,CC(=O)OCCC(C)OS(=O)(=O)c1ccc(C)cc1.CCc1ccc(O)c(C(=O)c2ccccc2)c1>>CCc1ccc(OC(C)CCOC(C)=O)c(C(=O)c2ccccc2)c1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160102083A1,C/C=C(/CCCN1CCN(C)CC1)c1scc(C(=O)OC)c1C>>CCC(CCCN1CCN(C)CC1)c1scc(C(=O)OC)c1C,[Pd],CO,,,,test
US20070293494A1,CC(C)(C)OC(=O)N1CCC[C@H]1CNc1ccnc(Nc2cccc(Cl)c2)n1>>Clc1cccc(Nc2nccc(NC[C@@H]3CCCN3)n2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05840732,CCCCCC=O.O=C1CSC(=O)N1CCCCSc1cccc2nccn12>>CCCCCC=C1SC(=O)N(CCCCSc2cccc3nccn23)C1=O,,CCO,,C1CCNCC1,,test
US20130217666A1,C#C[C@@](C)(O)c1ncccn1.NC(=O)c1nc2n(c1-c1nc(C3CC3)n[nH]1)CCOc1cc(F)c(Br)cc1-2>>C[C@@](O)(C#Cc1cc2c(cc1F)OCCn1c-2nc(C(N)=O)c1-c1nc(C2CC2)n[nH]1)c1ncccn1,,CN(C)C=O,,CC(C)NC(C)C,,test
US20110112063A1,C=CC#N.Cc1cc(Nc2nc(Nc3cc(C)c(C4CCNCC4)cc3F)ncc2Cl)n[nH]1>>Cc1cc(Nc2nc(Nc3cc(C)c(C4CCN(CCC#N)CC4)cc3F)ncc2Cl)n[nH]1,,CO,,,,test
US04123551,CC1(C)OC(=O)CC(=O)O1.O=C=Nc1ccc(C(F)(F)F)cc1>>CC1(C)OC(=O)C(C(=O)Nc2ccc(C(F)(F)F)cc2)=C(O)O1,,CS(C)=O,O,CCN(CC)CC,Cl,test
US20140005164A1,COC(=O)[C@@H]1CC[C@@H](CNc2nc(N(C)CCN(C)C)ccc2[N+](=O)[O-])CC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COC(=O)[C@@H]1CC[C@@H](Cn2c(=O)[nH]c3ccc(N(C)CCN(C)C)nc32)CC1,[Pd],C1CCOC1,,O,[H][H],test
US20100317647A1,COC(=O)C1CCC(OS(C)(=O)=O)C1.Sc1ccccc1Cl>>COC(=O)C1CCC(Sc2ccccc2Cl)C1,,C1CCOC1,,[H-].[Na+],,test
US20050288286A1,CCCCOC(=O)N(C)S(=O)(=O)NCC(=O)OCC>>CCOC(=O)CNS(=O)(=O)NC,,CO,,Cl,,test
US20100120751A1,CC(O)c1ccccc1C1(O)CCN(Cc2ccccc2)CC1>>CC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc21,CN(C)c1ccccn1,C1CCOC1,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20040014940A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)C[C@H](CN)CC(=O)O>>CC(C)CC(CNC(=O)OC(C)(C)C)CC(=O)O,,C1COCCO1,O,[Na+].[OH-],,test
US20150266872A1,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.O=C(c1cnc2c(Br)cc(C(F)(F)F)cn12)N1C[C@@H]2C[C@H]1CO2>>Cn1cc(-c2cc(C(F)(F)F)cn3c(C(=O)N4C[C@@H]5C[C@H]4CO5)cnc23)cn1,,COCCOC,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20020120006A1,Cc1ccc(CCCC(C)(C)O)cc1>>Cc1ccc2c(c1)C(C)(C)CCC2,,CCOCC,,O=S(=O)(O)O,,test
US04046900,Cc1[nH]c2ccccc2c1CCBr.Cc1ccc(C2CCNCC2)cc1>>Cc1ccc(C2CCN(CCc3c(C)[nH]c4ccccc34)CC2)cc1,,CN(C)C=O,,CCO,,test
US20080312234A1,CC(=NS(=O)C(C)(C)C)c1cc(F)c(NS(C)(=O)=O)c(F)c1>>CC(NS(=O)C(C)(C)C)c1cc(F)c(NS(C)(=O)=O)c(F)c1,,C1CCOC1,,CO,[BH4-].[Na+],test
US20140024650A1,CC(C)(C)OC(=O)N[C@H]1COCC[C@@H]1CO.Oc1ccc(-n2cc(Cl)cn2)cc1F>>CC(C)(C)OC(=O)N[C@H]1COCC[C@@H]1COc1ccc(-n2cc(Cl)cn2)cc1F,,Cc1ccccc1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20070203100A1,COc1ccc(C2CCCCC2)c(C)c1>>Cc1cc(O)ccc1C1CCCCC1,,ClCCl,,BrB(Br)Br,,test
US20120058270A1,CC(C)N.O=C(OC(=O)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)F>>CC(C)NC(=O)C(F)(F)C(F)(F)F,,CCOCC,,CCN(CC)CC,,test
US20090082354A1,CCOC(=O)c1nnc2c(-c3cccc(OC)c3)c(-c3ccncc3)nn2c1-c1ccc(N2CCN(C)CC2)cc1>>CN1CCN(c2ccc(-c3cnnc4c(-c5cccc(O)c5)c(-c5ccncc5)nn34)cc2)CC1,,CO,ClCCl,,,test
US20120270838A1,CC(C)(C)OC(=O)N1CCC2(CC1)N=C(c1cccc(Br)c1)NC2=O.Cc1noc(C)c1B(O)O>>Cc1noc(C)c1-c1cccc(C2=NC3(CCN(C(=O)OC(C)(C)C)CC3)C(=O)N2)c1,,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20120316161A1,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1Cl.COc1ccc(B(O)O)c(F)c1>>CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc(OC)cc1F,,COCCOC,O,CCN(C(C)C)C(C)C,,test
US20040106667A1,CS(=O)(=O)c1ccccc1S(=O)(=O)Cl.Nc1ccc2[nH]nc(-c3ccc(Cl)cc3)c2c1>>CS(=O)(=O)c1ccccc1S(=O)(=O)Nc1ccc2[nH]nc(-c3ccc(Cl)cc3)c2c1,,C1CCOC1,,O,c1ccncc1,test
US20030008884A1,Cc1cc(-c2nnc(C(C)(C)C)o2)ccc1[N+](=O)[O-]>>Cc1cc(-c2nnc(C(C)(C)C)o2)ccc1N,[Zn],CN(C)C=O,O,,,test
US20140329820A1,BrBr.COc1ccc(CCNC(C)=O)cc1OCc1ccccc1>>COc1cc(Br)c(CCNC(C)=O)cc1OCc1ccccc1,,ClC(Cl)Cl,,,,test
US20100216746A1,CCCCc1cc(Cl)cc(Oc2c(Cl)ccc(CNC(=O)c3c(Cl)ncn3COCC[Si](C)(C)C)c2F)c1>>CCCCc1cc(Cl)cc(Oc2c(Cl)ccc(CNC(=O)c3[nH]cnc3Cl)c2F)c1,,CCOC(C)=O,ClCCl,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20100286145A1,C=C(C)c1cncc([C@@H](C)N=[N+]=[N-])c1>>C=C(C)c1cncc([C@@H](C)N)c1,[Pd],CO,Cl,,,test
US04880819,NCC(=O)Nc1ccncc1.O=C(O)CN1CCCC1=O>>O=C(CN1CCCC1=O)NCC(=O)Nc1ccncc1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20120283264A1,CC(C)(C)OC(=O)N[C@H](c1cccc(Br)n1)[C@H](O)c1ccccc1>>O=C1N[C@H](c2cccc(Br)n2)[C@@H](c2ccccc2)O1,,O=C(O)C(F)(F)F,,O=C(n1ccnc1)n1ccnc1,,test
US20090247517A1,CN1CCNCC1.O=C(O)c1ccc(-n2ncc3c(=O)n(-c4ccc(Cl)cc4)c(-c4ccc(Cl)cc4Cl)nc32)cc1>>CN1CCN(C(=O)c2ccc(-n3ncc4c(=O)n(-c5ccc(Cl)cc5)c(-c5ccc(Cl)cc5Cl)nc43)cc2)CC1,,O=S(Cl)Cl,,,,test
US09163003B2,COc1ccc(C(=O)C2CCN(C3CCNC3=O)CC2)cc1.Cc1cc2c(=O)[nH]c(CCl)nc2s1>>COc1ccc(C(=O)C2CCN(C3CCN(CC4=NC5SC(C)=CC5C(=O)N4)C3=O)CC2)cc1,,C1CCOC1,CCOCC,[H-].[Na+],,test
US20090291971A1,COC(=O)c1sc2ncnc(On3nnc4cccnc43)c2c1C.O=[N+]([O-])c1cccc(B(O)O)c1>>COC(=O)c1sc2ncnc(Oc3cccc([N+](=O)[O-])c3)c2c1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120295897A1,NC(CCN1C(=O)C2(COc3cc4c(cc32)OCO4)c2ccccc21)=NO.O=C(CC(F)(F)F)OC(=O)CC(F)(F)F>>O=C1N(CCc2noc(C(F)(F)F)n2)c2ccccc2C12COc1cc3c(cc12)OCO3,,ClCCl,,CC(C)NC(C)C,,test
US05225418,CS(=O)CC(=O)c1ccccc1N.O=Cc1ccccc1SCc1ccccc1>>O=c1cc(-c2ccccc2SCc2ccccc2)[nH]c2ccccc12,,Cc1ccccc1,,C1CCNCC1,,test
US20130109682A1,CC(C)(C)[Si](C)(C)Cl.O=[N+]([O-])c1cnccc1[C@H]1CC(NCc2ccccc2)[C@H](O)[C@@H](C2CC2)O1>>CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](C2CC2)O[C@@H](c2ccncc2[N+](=O)[O-])C[C@@H]1NCc1ccccc1,,ClCCl,,c1c[nH]cn1,,test
US20080221114A1,C[C@@H]1C[C@H](C)CN(C(=O)C2Cc3ccccc3N2C(=O)OC(C)(C)C)C1>>C[C@@H]1C[C@H](C)CN(C(=O)C2Cc3ccccc3N2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050090483A1,COC(=O)CC(=O)CCl.Sc1nc[nH]n1>>COC(=O)CC(=O)CSc1nc[nH]n1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US04906621,CCOC(=O)C1CC(C=O)CCN1C(=O)OC(C)(C)C.O=CC=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)C1CC(C=CC=O)CCN1C(=O)OC(C)(C)C,,Cc1ccccc1,,,,test
US07612075B2,C#CCNCC(NC(=O)OCc1ccccc1)C(=O)OC.O=C(O)CBr>>C#CCN(CC(NC(=O)OCc1ccccc1)C(=O)OC)C(=O)CBr,,CCOCC,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20160083391A1,O=[N+]([O-])O.c1nc(C2CCCC2)c[nH]1>>O=[N+]([O-])c1[nH]cnc1C1CCCC1,,O=S(=O)(O)O,,[Na+].[OH-],,test
US04962017,CC(C)(C)C#CC(=O)O.O=S(Cl)Cl>>CC(C)(C)C#CC(=O)Cl,,ClCCl,,Cl,,test
US20100168154A1,Cc1cccc(CC#N)c1C(=O)c1ccccc1.Cl>>Cc1cccc2c1C(c1ccccc1)=NCC2.Cl,O=[Pt],CCO,,CCOC(C)=O,,test
US20100222366A1,CCOC(=O)C1=C(N[C@H](C)c2ccccc2)CCC2(C1)OCCO2>>CCOC(=O)[C@H]1CC2(CC[C@H]1N[C@H](C)c1ccccc1)OCCO2,[Pt],CCO,CCOC(C)=O,CC(=O)O,,test
US20160046563A1,Cl.O=C(O)c1cc(Br)cc(C(=O)O)c1F.O=S(Cl)Cl>>O=C(Cl)c1cc(Br)cc(C(=O)Cl)c1F,CN(C)C=O,,,,,test
US04588719,O=C1CCCc2ccc(O)cc21.O=C1c2ccccc2C(=O)N1CCCBr>>O=C1CCCc2ccc(OCCCN3C(=O)c4ccccc4C3=O)cc21,,CN(C)C=O,,O,C[O-].[Na+],test
US20140194469A1,N#Cc1ccnc(-n2nccc2-c2ccccc2)c1.O.[OH-]>>O=C(O)c1ccnc(-n2nccc2-c2ccccc2)c1,,O,,CCO,,test
US20120065196A1,CC(C)C(=N)N.CCOC(=O)C1CCC(=O)C(=CN(C)C)C1>>CCOC(=O)C1CCc2nc(C(C)C)ncc2C1,,CCO,,Cl,,test
US20100130557A1,C#Cc1cc(Cl)cc(S(=O)(=O)N(CC(=O)O)c2ccc3c(c2)c2ccccc2n3CC)c1>>CCc1cc(Cl)cc(S(=O)(=O)N(CC(=O)O)c2ccc3c(c2)c2ccccc2n3CC)c1,O=[Pt]=O,CCOC(C)=O,,[H][H],,test
US20160159815A1,CC(C)(C)OC(=O)N1CC=C(c2ccccn2)CC1.C[Si](C)(C)C(F)(F)F>>CC(C)(C)OC(=O)N1CCC2(c3ccccn3)C(C1)C2(F)F,,C1CCOC1,,[I-].[Na+],,test
US20090029994A1,CCCC(=O)N(CC)c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(OCCCC(=O)OCC)cn1>>CCCC(=O)N(CC)c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ncc(OCCCC(=O)O)cn1,,CCO,,CCOC(C)=O,[Na+].[OH-],test
US20040259910A1,COc1cccc(Cc2ncc(C=O)c3cc(OCc4ccccc4)c(OC)cc23)c1.O=[Se]=O>>COc1cccc(C(=O)c2ncc(C=O)c3cc(OCc4ccccc4)c(OC)cc23)c1,,CC(=O)O,,CCCCCC,CCOC(C)=O,test
US20120077799A1,BrCC1CCCO1.O=S1(=O)CCN2C=CC=C(c3ccc(O)cc3)C2=N1>>O=S1(=O)CCN2C=CC=C(c3ccc(OCC4CCCO4)cc3)C2=N1,,CS(C)=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20070099928A1,CC(C)(C)N.CS(=O)(=O)Oc1ccc(OCCc2ccc(CC(SCCc3ccc(O)cc3)C(=O)O)cc2)cc1>>CC(C)(C)N.CS(=O)(=O)Oc1ccc(OCCc2ccc(CC(SCCc3ccc(O)cc3)C(=O)O)cc2)cc1,,CCO,,,,test
US20110245205A1,CC(C)(C)OC(=O)N1CCC(C(C)(O)c2ncc(Br)s2)CC1.Nc1cccc(B(O)O)c1>>CC(C)(C)OC(=O)N1CCC(C(C)(O)c2ncc(-c3cccc(N)c3)s2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US20090149484A1,CC(C)(C)OC(=O)NCCCn1cnc2ccc(Oc3ccc(NC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)cc3)cc2c1=O.Cl>>[Cl-].[NH3+]CCCn1cnc2ccc(Oc3ccc(NC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)cc3)cc2c1=O,,C1COCCO1,Cl,,,test
US20120129851A1,NC(N)=O.Nc1cc(Br)c(F)cc1C(=O)O>>O=c1[nH]c(=O)c2cc(F)c(Br)cc2[nH]1,,O,,,,test
US20120020884A1,Cc1ccc(S(=O)(=O)OCCF)cc1.Nc1cccc(F)c1>>FCCNc1cccc(F)c1,,CCOC(C)=O,CN(C)C=O,Cc1cccc(C)n1,,test
US05935945,COc1ccc(NN=C(Cl)C(C)=O)cc1.CSc1ccc(S)cc1>>COc1ccc(NN=C(Sc2ccc(SC)cc2)C(C)=O)cc1,,CCO,,CCN(CC)CC,,test
US04148897,C1COCCN1.CCO.COc1ccc2c(c1[N+](=O)[O-])CCCC2=O>>COc1ccc2c(c1[N+](=O)[O-])CCC(CN1CCOCC1)C2=O,,CCOCC,O,Cl,O=C([O-])O.[Na+],test
US20150239878A1,COc1cc(Br)c(NC(C)=S)cc1OCc1ccccc1>>COc1cc2sc(C)nc2cc1OCc1ccccc1,,CN1CCCC1=O,,[H-].[Na+],,test
US20090275578A1,COc1cc(Br)cc(C)c1C(N)=O.O=NOS(=O)(=O)O>>COc1cc(Br)cc(C)c1C(=O)O,,ClCCl,O,,,test
US20080021217A1,CC(NC(=O)c1ccc(O)cc1O)C(=O)NN.N#Cc1ccncc1>>CC(NC(=O)c1ccc(O)cc1O)c1nc(-c2ccncc2)n[nH]1,,CCCCO,,C1CCC2=NCCCN2CC1,,test
US20090186886A1,CN(C)CCN.[O-][n+]1nc(Cl)nc2cc3c(cc21)OCCC3>>CN(C)CCNc1nc2cc3c(cc2[n+]([O-])n1)OCCC3,,COCCOC,,,,test
US20150031627A1,CO.Cc1ccc(S(=O)(=O)CC#N)cc1.O=Cc1cc(F)cc([N+](=O)[O-])c1>>O=[N+]([O-])c1cc(F)cc(-c2cnco2)c1,,COCCOC,,,,test
US20140194469A1,CC(c1ccccc1)c1cc(O)n(-c2cc(C#N)ccn2)n1.[N-]=[N+]=[N-]>>CC(c1ccccc1)c1cc(O)n(-c2cc(-c3nnn[nH]3)ccn2)n1,,CN(C)C=O,,[Cl-].[NH4+],,test
US20080064720A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1ccc2nc(Oc3ccccc3)ccc2c1>>O=S(=O)(Oc1ccc2nc(Oc3ccccc3)ccc2c1)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US20090093474A1,O=C(O)C1CCN(C2CCCC2)CC1.O=S(Cl)Cl>>O=C(Cl)C1CCN(C2CCCC2)CC1,,CN(C)C=O,Cc1ccccc1,Cl,,test
US05955632,CC(=O)O[C@H]1CC[C@@]2(C)[C@H](CC[C@H]3C4=CC[C@H](C(C)=O)[C@@]4(C)CC[C@@H]32)C1>>CC(=O)O[C@H]1CC[C@@]2(C)[C@H](CC[C@H]3C4=CC[C@@H](C(C)=O)[C@@]4(C)CC[C@@H]32)C1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20060084673A1,O=C1CN(C(=O)OCc2ccccc2)C(NCc2ccc(C(F)(F)F)cc2C(F)(F)F)=N1.O=Cc1ccc2ncccc2n1>>O=C1N=C(NCc2ccc(C(F)(F)F)cc2C(F)(F)F)NC1=Cc1ccc2ncccc2n1,,CC(C)O,,C1CCNCC1,,test
US20130331378A1,COCOc1ccccc1S.O=Cc1cccc(Br)n1>>COCOc1ccccc1Sc1cccc(C=O)n1,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20060293519A1,Cc1cc(OCC(F)(F)F)c(NC(=O)CBr)c(OCC(F)(F)F)n1.OCCN1CCNCC1>>Cc1cc(OCC(F)(F)F)c(NC(=O)CN2CCN(CCO)CC2)c(OCC(F)(F)F)n1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20040235839A1,O=C(Nc1cncc2[nH]c3c([N+](=O)[O-])cc(Cl)cc3c12)C(F)(F)F>>Nc1cc(Cl)cc2c1[nH]c1cncc(NC(=O)C(F)(F)F)c12,,CO,,,,test
US20150175557A1,CSc1ncc(C#N)c(N[C@H]2CCC[C@H](O)C2(C)C)n1.NCCC1C(=O)Nc2cc(F)ccc21>>CC1(C)[C@@H](O)CCC[C@@H]1Nc1nc(NCCC2C(=O)Nc3cc(F)ccc32)ncc1C#N,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,Cl,test
US20060135484A1,CCC(CC)(c1ccc(OCC(O)C(C)(C)C)c(C)c1)c1cc(C)c(C(=O)NN)s1.S=C=S>>CCC(CC)(c1ccc(OCC(O)C(C)(C)C)c(C)c1)c1cc(C)c(-c2n[nH]c(=S)o2)s1,,CO,,[K+].[OH-],,test
US20070238730A1,CC(C)(C)OC(=O)NCCC(N)=S.CCC(=O)CBr>>Br.CCc1csc(CCN)n1,,CCO,,,,test
US20130196970A1,CC(C)(C)OC(=O)N1CC(N[C@H]2CCN(C(=O)OCc3ccccc3)C2)C1>>CC(C)(C)OC(=O)N1CC(N[C@H]2CCNC2)C1,[Pd],CCO,,[H][H],,test
US05384192,C=Cc1ccc(O)cc1.CC(C)(C)[Si](C)(C)Cl>>C=Cc1ccc(O[Si](C)(C)C(C)(C)C)cc1,,ClCCl,,CCN(CC)CC,,test
US04678502,COCCc1ccccc1S(=O)(=O)NC(C)(C)C>>COCCc1ccccc1S(N)(=O)=O,,O=C(O)C(F)(F)F,,,,test
US20110144136A1,Br.CCN1CCCC(CO)C1>>CCN1CCCC(CBr)C1,,ClCCl,,O,O=C([O-])[O-].[K+].[K+],test
US20140142122A1,COc1ccc(N)cc1.Cc1cc(C)n2nc(SCC(=O)O)nc2n1>>COc1ccc(NC(=O)CSc2nc3nc(C)cc(C)n3n2)cc1,,CN(C)C=O,,,,test
US20080167287A1,Nc1ncc(-c2ccc(C3(C(=O)O)CC3)cc2)cn1.O=CC(Cl)C1(c2ccc3ncccc3c2)CC1>>O=C(O)C1(c2ccc(-c3cnc4ncc(C5(c6ccc7ncccc7c6)CC5)n4c3)cc2)CC1,,CCO,,,,test
US06468974B1,CC(C)(C)OC(=O)NC(C)(C)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC[C@@H]1C(=O)O.NC(=O)C1CCCNC1>>CC(C)(N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC[C@@H]1C(=O)O.CC1CCCN(C(N)=O)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05563162,CI.Cc1ccc2cccc(OCc3c(Cl)ccc(NC(=O)CN4C(=O)c5ccccc5C4=O)c3Cl)c2n1>>Cc1ccc2cccc(OCc3c(Cl)ccc(N(C)C(=O)CN4C(=O)c5ccccc5C4=O)c3Cl)c2n1,,O,,CN(C)C=O,[H-].[Na+],test
US20160212997A1,COC(CNCc1ccc(Cl)nc1)OC.Cc1ccccc1.O=C1COC(=O)C1>>O=C1OCc2c1ccn2Cc1ccc(Cl)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090131468A1,COC(=O)c1ccc2oc(-c3cccc(OC)c3)cc2c1>>COc1cccc(-c2cc3cc(C(=O)O)ccc3o2)c1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20090048238A1,COC(=O)c1c(C)cc(-c2cccc(C(F)(F)F)c2)nc1OC>>Cc1cc(-c2cccc(C(F)(F)F)c2)[nH]c(=O)c1C(=O)O,,ClCCl,,BrB(Br)Br,CO,test
US20100216788A1,Cc1nccn1Cc1cccc(Oc2ccc([N+](=O)[O-])cc2Cl)c1>>Cc1nccn1Cc1cccc(Oc2ccc(N)cc2Cl)c1,[Pt],CO,,,,test
US20100210641A1,CNC(=O)c1cccc(-c2ccn3c(Br)cnc3c2)c1.OB(O)c1cccc(-n2cccn2)c1>>CNC(=O)c1cccc(-c2ccn3c(-c4cccc(-n5cccn5)c4)cnc3c2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US20090118263A1,CN(C(=O)OC(C)(C)C)C1CCNCC1.COC(=O)Cc1cccc(OCCBr)c1>>COC(=O)Cc1cccc(OCCN2CCC(N(C)C(=O)OC(C)(C)C)CC2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06022906,BrCc1ccccc1.CC(C(=O)c1ccc(F)cc1)N(C)C>>CN(C)C(C)(Cc1ccccc1)C(=O)c1ccc(F)cc1,,CC(=O)N(C)C,,,,test
US07553969B1,CC(C)[C@@H](C(=O)N(C)[C@@H](Cc1ccc(O)c(C(C)(C)C)c1)C(N)=O)N(C)C(=O)[C@H](Cc1cccc(F)c1)NC(=O)OC(C)(C)C>>CC(C)[C@@H](C(=O)N(C)[C@@H](Cc1ccc(O)c(C(C)(C)C)c1)C(N)=O)N(C)C(=O)[C@@H](N)Cc1cccc(F)c1,,ClCCl,O=C(O)C(F)(F)F,,,test
US04675332,BrCc1ccccc1.COC(=O)c1c(O)c2cc(OC)ccc2n1-c1ccccc1>>COC(=O)c1c(OCc2ccccc2)c2cc(OC)ccc2n1-c1ccccc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04285944,CC1OC2(C)CCC1c1c2nnc(-c2ccccc2)[n+]1[O-]>>CC1OC2(C)CCC1c1nc(-c3ccccc3)nnc12,[Pd],CCO,,C1=CCCCC1,,test
US20120108422A1,CC(Cc1ccccc1Cl)CC1(C(C)(C)C)CO1.c1nc[nH]n1>>CC(Cc1ccccc1Cl)CC(O)(Cn1cncn1)C(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US05434186,CC(=O)OCCCCCBr.O=Cc1cccc(O)c1>>CC(=O)OCCCCCOc1cccc(C=O)c1,,CCOCC,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20100160308A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCCCN1CCOCC1>>Cc1ccc(S(=O)(=O)OCCCN2CCOCC2)cc1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20160024095A1,CCOC(=O)Cl.Cc1cnc(-c2cc(N3CCc4nc(N)ncc4C3)ncc2Cl)c(C)c1>>CCOC(=O)Nc1ncc2c(n1)CCN(c1cc(-c3ncc(C)cc3C)c(Cl)cn1)C2,,C1COCCO1,,CCN(C(C)C)C(C)C,ClCCl,test
US06583090B1,Cl.Nc1ccc(O)c(Cl)c1.O=N[O-]>>Cl.N#[N+]c1ccc(O)c(Cl)c1,,Cl,O,Cl[Sn]Cl,,test
US04032323,CN.COC(=O)c1c(C)nsc1NC(=O)Oc1ccccc1>>CNC(=O)Nc1snc(C)c1C(=O)OC,,CCO,O,Br,,test
US20090163506A1,CC(C)(C)OC(=O)OC(=O)OC(=O)OC(C)(C)C.N[C@@H]1CCN(c2ccc(C(F)(F)F)cn2)C1.Nc1cccc2cnccc12>>O=C(Nc1cccc2cnccc12)N[C@@H]1CCN(c2ccc(C(F)(F)F)cn2)C1,,ClCCl,,,,test
US05747235,CCN(CC)CC.COc1ccc(N)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccc(N)cc1.NC(=O)C(F)(F)F,,C1CCOC1,,,,test
US20160184318A1,C1COCCN1.Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)N2CCC(CC(=O)O)CC2)n1>>Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)N2CCC(CC(=O)N3CCOCC3)CC2)n1,,CN1CCCC1=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070219230A1,O=[N+]([O-])c1cc(F)cnc1Cl.c1ccc2c(c1)CCNC2>>O=[N+]([O-])c1cc(F)cnc1N1CCc2ccccc2C1,,O,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20050107377A1,Fc1ccc2c(-c3ccc(OC[C@H]4CO4)cc3)noc2c1.c1cnc(N2CCNCC2)nc1>>O[C@@H](COc1ccc(-c2noc3cc(F)ccc23)cc1)CN1CCN(c2ncccn2)CC1,,CCO,CN(C)C=O,,,test
US05792769,CI.Cc1ccc(NS(=O)(=O)c2ccccc2)c(OCCCCNC(=O)OC(C)(C)C)c1>>Cc1ccc(N(C)S(=O)(=O)c2ccccc2)c(OCCCCNC(=O)OC(C)(C)C)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110068683A1,Brc1ccc2ccccc2c1.O=C1c2ccccc2Cc2cc(-c3ccc4ccccc4c3)ccc21>>c1ccc2cc(-c3ccc4c(-c5ccc6ccccc6c5)c5ccccc5cc4c3)ccc2c1,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US06187802B1,O=C(CBr)C1(c2ccc(Cl)c(Cl)c2)CCCC1.S=C1NCCN1>>Br.Clc1ccc(C2(C3=CSC4=NCCN34)CCCC2)cc1Cl,,CC(=O)O,,CCO,,test
US20060046977A1,C[Si](C)(C)c1oc2c(c1-c1ccccc1)c(=O)ccn2Cc1ccccc1.O=C1CCC(=O)N1I>>O=c1ccn(Cc2ccccc2)c2oc(I)c(-c3ccccc3)c12,,CN(C)C=O,,,,test
US20030199506A1,CCc1noc(C(O)[C@H](CC)NC(=O)OC(C)(C)C)n1>>CCc1noc([C@@H](O)C(N)CC)n1,,Cc1ccccc1,ClCCl,O=C(O)C(F)(F)F,,test
US20030060460A1,COC(=O)c1ccc(OCc2cc(Cl)ccc2N)cc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>COC(=O)c1ccc(OCc2cc(Cl)ccc2NS(=O)(=O)c2ccc(Cl)cc2)cc1,,ClCCl,c1ccncc1,O,,test
US20140206663A1,C=C(C)c1cc2c(cc1OC1(C)CN(C(=O)OC(C)(C)C)C1)N1C(=NNC(=O)C1C)CO2>>CC(C)c1cc2c(cc1OC1(C)CN(C(=O)OC(C)(C)C)C1)N1C(=NNC(=O)C1C)CO2,[Pd],CO,,,,test
US20050234109A1,O=S(=O)(c1ccc(Cl)cc1)C(CCCCO)c1cc(F)ccc1F>>O=S(=O)(c1ccc(Cl)cc1)C1(c2cc(F)ccc2F)CCCC1,,Cc1ccccc1,,CCCCP(=CC#N)(CCCC)CCCC,,test
US20150119405A1,CCOC(=O)C1CCC(O)C(N=[N+]=[N-])C1>>CCOC(=O)C1CCC(O)C(N)C1,[Pd],CCOC(C)=O,,,,test
US20080139548A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1cc2cc(Cl)cc(C)c2[nH]1>>CCOC(=O)c1cc2cc(Cl)cc(C)c2n1C(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,Cl,test
US04806608,CCC=COc1ccc([N+](=O)[O-])cc1>>CCC=COc1ccc(N)cc1,[Fe],O,,Cl,[Na+].[OH-],test
US20110160212A1,BrP(Br)Br.OCc1cc(F)ccc1Br>>Fc1ccc(Br)c(CBr)c1,,COCCOC,O,,,test
US20130261151A1,CC(O)CCCn1c(Cn2c(=O)n(C3CC3)c3ccncc32)nc2nc(Cl)ccc21.CCOCC>>CC(C)(O)CCCn1c(Cn2c(=O)n(C3CC3)c3ccncc32)nc2nc(Cl)ccc21,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20060030613A1,CC(C)(C)c1ccc(CNCC(O)c2ccc(Cl)c(Cl)c2)cc1.O=C(O)c1cc(Cl)cc2cc[nH]c12>>CC(C)(C)c1ccc(CN(CC(O)c2ccc(Cl)c(Cl)c2)C(=O)c2cc(Cl)cc3cc[nH]c23)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20090209540A1,C=Cc1cnc(-c2ccc(C)nc2)c(Cl)c1.O=[Se]=O>>C=Cc1cnc(-c2ccc(C=O)nc2)c(Cl)c1,,C1COCCO1,,,,test
US20150306102A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1nn2c(C(F)(F)F)cc(C(F)(F)F)nc2c1-c1ccccc1>>O=S(=O)(Oc1nn2c(C(F)(F)F)cc(C(F)(F)F)nc2c1-c1ccccc1)C(F)(F)F,,ClCCl,,CCN(CC)CC,O,test
US20140275026A1,COc1nccc2c(-c3cc(N)ccc3Oc3ccc(C#N)cc3)cn(C)c12.CS(=O)(=O)Cl>>COc1nccc2c(-c3cc(NS(C)(=O)=O)ccc3Oc3ccc(C#N)cc3)cn(C)c12,,C1COCCO1,ClCCl,CCN(CC)CC,[Na+].[OH-],test
US20100081692A1,COC(=O)CCc1ccccc1O.ClCCCBr>>COC(=O)CCc1ccccc1OCCCCl,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US06130338,C/C(=C\CO)CO.NCc1ccccc1>>CC1=CCN(Cc2ccccc2)C1,,CCOC(C)=O,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20100009066A1,COCCOCCOc1ccccc1Br.OB(O)c1ccsc1>>COCCOCCOc1ccccc1-c1ccsc1,,COCCOC,,N#N,,test
US20080207635A1,CCN1CCC2(CCN(c3cc(C)c(N)c([N+](=O)[O-])c3)C2)C1.O=Cc1c(I)ccnc1Cl>>CCN1CCC2(CCN(c3cc(C)c4nc(-c5c(I)ccnc5Cl)[nH]c4c3)C2)C1,[Pd],CO,,CC(=O)O,,test
US03959475,CN1CCC2(CC1)OC(O)(c1ccccc1)c1ccccc12>>CN1CCC(O)(c2ccccc2C(O)c2ccccc2)CC1,,O,,C1CCOC1,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050153942A1,Cc1nc2[nH]cnc2cc1Br.O=C(OO)c1cccc(Cl)c1>>Cc1c(Br)cc2nc[nH]c2[n+]1[O-],,ClCCl,,,,test
US20110144110A1,CC(=O)Cl.Nc1ccc([N+](=O)[O-])cc1>>CC(=O)Nc1ccc([N+](=O)[O-])cc1,,ClCCl,c1ccncc1,,,test
US20040220402A1,CCOC1=CC(=O)CC1.O=C1CCC(=O)N1Br>>CCOC1=C(Br)C(=O)CC1,,ClC(Cl)(Cl)Cl,,,,test
US20130317001A1,COC(=O)Cl.N#CC1C2CC3CC(C2)CC1C3>>COC(=O)C1(C#N)C2CC3CC(C2)CC1C3,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20120088750A1,CCN=C=O.COc1c(Br)cc2nc(N)sc2c1Br>>CCNC(=O)Nc1nc2cc(Br)c(OC)c(Br)c2s1,,CS(C)=O,O,CCN(CC)CC,,test
US09012412B2,Cc1cc(O)c(C2OC(CO)CC(O)C2O)cc1Cc1cc2ccccc2s1.O=C(Cl)c1ccccc1>>COc1cc(O)c(C2OC(CO)CC(O)C2O)cc1Cc1cc2ccccc2s1,,c1ccncc1,,,,test
US20050143421A1,CC(=O)NC[C@H]1CN(c2ccc(N3CCC4(CC3)CO4)cc2)C(=O)O1.[C-]#N>>CC(=O)NC[C@H]1CN(c2ccc(N3CCC(O)(CC#N)CC3)cc2)C(=O)O1,,CN(C)C=O,,CO,,test
US20120077781A1,Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCCCCCC(=O)OC(C)(C)C)c2cc1NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCCCCCC(=O)O)c2cc1NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO,,C1COCCO1,Cl,,,test
US20090269301A1,CCOC(=O)C(=O)CC(=O)CC(C)C.Nc1ccc2[nH]cnc2c1.O=Cc1ccc2cccc(O)c2n1>>CC(C)CC(=O)C1=C(O)C(=O)N(c2ccc3[nH]cnc3c2)C1c1ccc2cccc(O)c2n1,,CCO,,,,test
US06300363B1,CCOC(=O)n1c(C(=O)c2ccccc2)c(NC(C)=O)c2c(Cl)cccc21>>CC(=O)Nc1c(C(=O)c2ccccc2)[nH]c2cccc(Cl)c12,,CCCCCC,CCOC(C)=O,[Br-].[K+],,test
US20080090863A1,O=C(NC[C@@H]1CC[C@H](NCc2ccccc2)CC1)OCc1ccccc1>>NC[C@@H]1CC[C@H](NCc2ccccc2)CC1,,CO,O,Cl,[K+].[OH-],test
US20160229807A1,CCOC(=O)CC1CCCc2c(-c3ccc(C(F)(F)F)cc3F)cncc21.CN>>CNC(=O)CC1CCCc2c(-c3ccc(C(F)(F)F)cc3F)cncc21,,C1CCOC1,,C[Al](C)C,,test
US05344843,CS(=O)(=O)OCCOc1ccc2ccccc2c1.Oc1cc(Cl)c(Br)c(Cl)c1>>Clc1cc(OCCOc2ccc3ccccc3c2)cc(Cl)c1Br,,CN(C)C=O,,[H-].[Na+],,test
US20160185999A1,CCC(C)=O.CCCCCC.CO.O>>COCC(C)OC(C)=O,,CCCCCC,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20160158207A1,CC(C)(C)OC(=O)NCCn1cc(B2OC(C)(C)C(C)(C)O2)cn1.CI>>CN(CCn1cc(B2OC(C)(C)C(C)(C)O2)cn1)C(=O)OC(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20030232863A1,Brc1ccc(Br)cc1.CC(F)(F)C[C@@H](CO[Si](C)(C)C(C)(C)C)/N=C/C(F)(F)F>>CC(F)(F)C[C@@H](CO)N[C@@H](c1ccc(Br)cc1)C(F)(F)F,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20080312226A1,CC(=O)Oc1cccc(C(=O)O)c1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>CC(=O)Oc1cccc(NC(=O)N2CCN(c3nc(-c4ccccc4)ns3)CC2)c1,,Cc1ccccc1,O,CCN(CC)CC,,test
US20020107251A1,CCOC(=O)c1cccc(N)c1.O=C(Cl)c1ccccc1>>CCOC(=O)c1cccc(NC(=O)c2ccccc2)c1,,ClCCl,O,CCN(CC)CC,CCOC(C)=O,test
US20060135782A1,COc1cc2ncnc(Nc3nc4ccc(N)cc4s3)c2cc1OC.O=C=Nc1cccc(C(F)(F)F)c1>>COc1cc2ncnc(Nc3nc4ccc(NC(=O)Nc5cccc(C(F)(F)F)c5)cc4s3)c2cc1OC,,O,,,,test
US06291530B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=c1[nH]cc(Br)cc1O>>CC(C)(C)OC(=O)Oc1cc(Br)c[nH]c1=O,,C1COCCO1,O,[Na+].[OH-],,test
US20020040025A1,NC(=O)c1nc(Cl)c(N)nc1N.OB(O)c1ccc(Oc2ccccc2)cc1>>NC(=O)c1nc(-c2ccc(Oc3ccccc3)cc2)c(N)nc1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],test
US20150232472A1,COC(=O)C(=O)C(C)Br.Nc1ccc(Cl)nn1>>COC(=O)c1nc2ccc(Cl)nn2c1C,,COCCOC,,,,test
US20030144282A1,CC(=O)OC(C)=O.COC(=O)c1ccc(O)cc1O>>COC(=O)c1ccc(OC(C)=O)cc1O,CN(C)c1ccncc1,CCOCC,,CCN(CC)CC,,test
US05763461,Cc1cc(-c2noc(C(F)(F)F)n2)cc(C)c1OCCCc1ccc(C)[n+]([O-])c1.O=P(Cl)(Cl)Cl>>Cc1cc(-c2noc(C(F)(F)F)n2)cc(C)c1OCCCc1ccc(CCl)nc1,,ClCCl,,CCN(CC)CC,,test
US20090269305A1,CC(C)c1csc(C(=O)O)n1.COc1ccc(C(C)=O)c(N)c1C>>COc1ccc(C(C)=O)c(NC(=O)c2nc(C(C)C)cs2)c1C,,Cc1ccccc1,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20070010670A1,COC(=O)c1ccc(OC)c(Cl)c1.O=[N+]([O-])O>>COC(=O)c1cc(Cl)c(OC)c([N+](=O)[O-])c1,,O=S(=O)(O)O,,,,test
US20070112005A1,NCc1nccnc1Cl.O=C1CC(C(=O)ON2C(=O)CCC2=O)C1>>O=C1CC(c2ncc3c(Cl)nccn23)C1,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20070116643A1,CC(C)(C)OC(=O)NCC[C@H](O)c1cccs1.Cl>>Cl.NCC[C@H](O)c1cccs1,,C1COCCO1,,,,test
US20060122168A1,O=C1Nc2cc(F)ccc2O[C@@H](Cc2ccccc2)[C@H]1N(Cc1ccccc1)Cc1ccccc1>>N[C@H]1C(=O)Nc2cc(F)ccc2O[C@H]1Cc1ccccc1,[Pd],CO,,,,test
US20110245224A1,CO.O=C(O)c1ccc(F)c(F)c1O>>COC(=O)c1ccc(F)c(F)c1O,,O,,O=S(=O)(O)O,,test
US20130331382A1,CC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Cn1nc(Cl)c(Cl)cc1=O>>CC(=O)Nc1ccc(-c2cc(=O)n(C)nc2Cl)cc1,,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05646308,CNC(=S)C1=C(O)C2(CCOCC2)Oc2ccc([N+](=O)[O-])cc21>>CNC(=S)C1c2cc([N+](=O)[O-])ccc2OC2(CCOCC2)C1O,,CO,,C1CCOC1,[BH4-].[Na+],test
US05536725,BrCc1ccccc1.OCc1ccccc1C1CCC2(CC1)OCCO2>>c1ccc(COCc2ccccc2C2CCC3(CC2)OCCO3)cc1,,Cc1ccccc1,,[H-].[Na+],,test
US05594011,CN1CCCC1c1cncc(-c2ccc(O)cc2)c1.O=C(O)/C=C/C(=O)O>>CN1CCCC1c1cncc(-c2ccc(O)cc2)c1.O=C(O)/C=C/C(=O)O,,CO,,,,test
US06040339,CCCCCC(CC(=O)Nc1cc(C(N)=O)ccc1C(C)(C)C)c1ccc(OCc2ccccc2)cc1OC>>CCCCCC(CC(=O)Nc1cc(C(N)=O)ccc1C(C)(C)C)c1ccc(O)cc1OC,[Pd],CCO,,[H][H],,test
US07303592B2,Nc1cccc(Nc2ccc([N+](=O)[O-])cn2)c1>>Nc1ccc(Nc2cccc(N)c2)nc1,[Pd],CO,,O=C=O,,test
US04012416,CCOC(=N)c1ccc(-c2cccc(C(F)(F)F)c2)o1.COC(CN)OC.Cl>>COC(CN=C(N)c1ccc(-c2cccc(C(F)(F)F)c2)o1)OC.Cl,,CCO,,,,test
US20070123510A1,CC(C)(C)C1CCC(=O)CC1.CCOC(=O)C(F)(F)F>>CC(C)(C)C1CCC(=O)C(C(=O)C(F)(F)F)C1,,CCOCC,,O,C[O-].[Na+],test
US20150299193A1,CCOC(=O)c1cc(Cl)ccc1[N+](=O)[O-].Oc1ccccc1>>CCOC(=O)c1cc(Oc2ccccc2)ccc1[N+](=O)[O-],,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20020147302A1,COC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C.Cl>>COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C.Cl,,COC(C)(C)C,,CCOC(C)=O,,test
US20150336953A1,CCNc1nc(SC)nc(N)c1Br.O=C(OO)c1cccc(Cl)c1>>CCNc1nc(S(C)=O)nc(N)c1Br,,ClCCl,,,,test
US20060106020A1,CCI.Oc1cc(-c2[nH]c(=S)[nH]c2-c2ccc(F)cc2)ccn1>>CCSc1nc(-c2ccc(F)cc2)c(-c2ccnc(O)c2)[nH]1,,C1CCOC1,C1CCOC1,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20040171651A1,CC1(C)ON=C(c2ccc(Cl)cc2)N1N.CCc1ccc(C(=O)Cl)cc1>>CCc1cccc(C(=O)NN2C(c3ccc(Cl)cc3)=NOC2(C)C)c1,,CCOC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04051248,O=C1c2cc(F)ccc2CCC1CN1CCC2(CC1)C(=O)NCN2c1ccccc1>>O=C1NCN(c2ccccc2)C12CCN(CC1CCc3ccc(F)cc3C1O)CC2,,CO,O,[BH4-].[Na+],,test
US20040242604A1,C1COCCN1.Cc1cc(Nc2ncnc3cnc(F)cc23)ccc1OC1CCN(C(=O)OC(C)(C)C)CC1>>Cc1cc(Nc2ncnc3cnc(N4CCOCC4)cc23)ccc1OC1CCNCC1,,CCOC(C)=O,CS(C)=O,CCN(CC)CC,,test
US20060106048A1,CCOC(=O)/C(C)=C/c1ccc(C2=NC(C)(C)Cc3cc(OCC)c4c(c32)CC(C)(C)O4)cc1>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(/C=C(\C)C(=O)O)cc1)=NC(C)(C)C2,,CCO,,Cl,[Na+].[OH-],test
US05140011,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O.CC(C)[C@@H](CCOc1ccccc1)C[C@H](O)[C@@H](N)CC1CCCCC1>>CC(C)[C@@H](CCOc1ccccc1)C[C@H](O)[C@H](CC1CCCCC1)NC(=O)C(Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C,,CC#N,CCOC(C)=O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20070254868A1,ClCCN1CCCC1.Ic1cn[nH]c1>>Ic1cnn(CCN2CCCC2)c1,,CN(C)C=O,,[H-].[Na+],,test
US20120330012A1,C[Si](C)(C)CCOCn1ccc2c(C(=O)C3CCCCC3)ncnc21.NN>>C[Si](C)(C)CCOCn1ccc2c(C(=NN)C3CCCCC3)ncnc21,,CO,,,,test
US20060148858A1,CC(C)c1nn(-c2ccc(Br)cn2)cc1CCCO.COC(=O)Cc1cccc(OC)c1O>>COc1cccc(CC(=O)O)c1OCCCc1cn(-c2ccc(Br)cn2)nc1C(C)C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US07790709B2,CN.O=Cc1cc2cnccc2s1>>CNCc1cc2cnccc2s1,,CO,,[BH4-].[Na+],,test
US06326359B1,COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CN)nc32)[C@H](O)[C@@H]1O.COc1ccc(C=O)cc1OC>>COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CNCc4ccc(OC)c(OC)c4)nc32)[C@H](O)[C@@H]1O,,C1CCOC1,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20040147739A1,Nc1ccccc1S(N)(=O)=O.O=C1CCC(=O)N1Cl>>Nc1ccc(Cl)cc1S(N)(=O)=O,,ClC(Cl)Cl,,,,test
US20050026929A1,CO.Cl.N#Cc1ccc(CN2C(=O)c3ccccc3C2=O)cc1>>COC(=N)c1ccc(CN2C(=O)c3ccccc3C2=O)cc1.Cl,,CO,,CCOCC,,test
US20040204427A1,COc1ccc(N)cc1OC.COc1ccc(N2Cc3cnc(Cl)nc3N([C@@H]3CC[C@@H](O[Si](C)(C)C(C)(C)C)CC3)C2=O)c(F)c1>>COc1ccc(N2Cc3cnc(Nc4ccc(OC)c(OC)c4)nc3N([C@@H]3CC[C@@H](O)CC3)C2=O)c(F)c1,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20040176617A1,CO.O=C(O)c1ccccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12>>COC(=O)c1ccccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12,,CO,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US05006555,CCOC(=O)Cl.Oc1c(Cc2ccccc2)ccc2ccccc12>>CCOC(=O)Oc1c(Cc2ccccc2)ccc2ccccc12,,ClCCl,,CCN(CC)CC,O,test
US05716965,CN(C)C(=O)[C@H]1CN2CC[C@@H]1C(=O)C2C(c1ccccc1)c1ccccc1.COc1ccc(OC)c(CN)c1>>COc1ccc(OC)c(CN[C@H]2[C@H]3CCN(C[C@@H]3C(=O)N(C)C)[C@H]2C(c2ccccc2)c2ccccc2)c1,,CC(=O)O,Cc1ccccc1,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04312876,CCOCC.CN1CC[C@H](O)[C@H](c2ccccc2)C1.Cl.Oc1ccc(O)c(-c2ccccc2COCc2ccccc2-c2cc(O)ccc2O)c1.c1ccccc1>>CN1CC[C@@H](Oc2ccc(OCc3ccccc3)cc2)[C@H](c2ccccc2)C1.Cl,,CCOCC,c1ccccc1,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080027124A1,NC(=O)c1[nH]c2ccc(C=O)cc2c1Sc1ccccc1.Nc1cccc(C(F)(F)F)c1>>NC(=O)c1[nH]c2ccc(CNc3cccc(C(F)(F)F)c3)cc2c1Sc1ccccc1,,CO,ClCCl,,,test
US05929097,COC(=O)c1cccc(C)c1NS(=O)(=O)c1ccc(OC)cc1.O=C1CCC(=O)N1Br>>COC(=O)c1cc(Br)cc(C)c1NS(=O)(=O)c1ccc(OC)cc1,CC(C)(C#N)N=NC(C)(C)C#N,ClC(Cl)Cl,,,,test
US20020028801A1,CC(C)(C)NC(=O)[C@@H](N)Cc1ccc(OCc2ccccc2)cc1.Cl>>CC(C)(C)NC(=O)[C@@H](N)Cc1ccc(OCc2ccccc2)cc1.Cl,,CCOCC,,,,test
US20100160258A1,CON(C)C(=O)[C@@H]1CC[C@H](OCc2ccccc2)CC1.[Li]C>>CC(=O)[C@@H]1CC[C@H](OCc2ccccc2)CC1,,C1CCOC1,,Cl,,test
US04990531,O=C1CCCN1.O=S(=O)(c1ccccc1)C1CCC(Cl)C1>>O=C1CCCN1S(=O)(=O)c1ccccc1C1CCCC1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US06281363B1,CC(C)C[C@@H](C(=O)NN)[C@H](C/C=C/c1ccccc1)C(=O)OC(C)(C)C.COC(=O)CNS(=O)(=O)Cl>>COC(=O)CNS(=O)(=O)NNC(=O)[C@H](CC(C)C)[C@H](C/C=C/c1ccccc1)C(=O)OC(C)(C)C,,CCOC(C)=O,ClCCl,c1ccncc1,,test
US20130115190A1,CC(C)(C)OC(=O)NS(=O)(=O)C1(CO)CC1.CCN(CC)S(F)(F)F>>CC(C)(C)OC(=O)NS(=O)(=O)C1(CF)CC1,,ClCCl,,,,test
US05952331,CC(C)c1cc(-c2ccc(F)c3ccccc23)nc(S(C)(=O)=O)n1.CCN>>CCNc1nc(-c2ccc(F)c3ccccc23)cc(C(C)C)n1,,CCO,,,,test
US20040102634A1,CC(C)OC(C(=O)N1C(=O)OCC1Cc1ccccc1)C(O)c1cccc(OCc2ccccc2)c1.CS(=O)(=O)Cl>>CC(C)O[C@H](C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1)C(OS(C)(=O)=O)c1cccc(OCc2ccccc2)c1,,CCOC(C)=O,c1ccncc1,,,test
US04189471,Cc1ccc(S(=O)(=O)O[C@H]2CC[C@@]3(C)C(=CC[C@H]4[C@@H]5CC[C@H]([C@H](C)CCCC(C)C)[C@@]5(C)CC[C@@H]43)C2)cc1.OCCCCCCO>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](OCCCCCCO)CC[C@]4(C)[C@H]3CC[C@]12C,,CCCCCC,,C1COCCO1,,test
US20030149089A1,Ic1c[nH]cn1.OB(O)c1ccsc1>>c1nc(-c2ccsc2)c[nH]1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090192138A1,CC(C)=CCn1c(Br)c(C#N)c2nc[nH]c(=O)c21.COc1cccc(C(=O)CBr)c1>>COc1cccc(C(=O)Cn2cnc3c(C#N)c(Br)n(CC=C(C)C)c3c2=O)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130102584A1,O=C(O)c1ccc(-c2cccc(C(F)(F)F)c2)cc1.O=C(c1nccs1)N1CCC(C2CNC2)CC1>>O=C(c1ccc(-c2cccc(C(F)(F)F)c2)cc1)N1CC(C2CCN(C(=O)c3nccs3)CC2)C1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20010027196A1,Nc1nc(OS(=O)(=O)C(F)(F)F)c([N+](=O)[O-])c(-c2ccco2)n1.OC1CCCCC1>>Nc1nc(OC2CCCCC2)c([N+](=O)[O-])c(-c2ccco2)n1,,COCCOC,,C1CCC2=NCCCN2CC1,,test
US20050113379A1,COC[C@H](C)Nc1cncc(Cl)n1.O=C1CCC(=O)N1Br>>COC[C@H](C)Nc1cnc(Br)c(Cl)n1,,ClC(Cl)Cl,,,,test
US20130045986A1,CS(=O)(=O)c1ccc(-c2nc3cc(C4CCNCC4)ccc3o2)c(F)c1.O=C(Cl)OCc1ccccc1>>CS(=O)(=O)c1ccc(-c2nc3cc(C4CCN(C(=O)OCc5ccccc5)CC4)ccc3o2)c(F)c1,,ClCCl,,Cc1ccccc1,O=C(O)C(F)(F)F,test
US20070173519A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOc1ccc(Nc2c(CCCO[Si](C)(C)C(C)(C)C)c(Cl)nc3ccnn23)cc1>>CCOc1ccc(N(C(=O)OC(C)(C)C)c2c(CCCO[Si](C)(C)C(C)(C)C)c(Cl)nc3ccnn23)cc1,,C1COCCO1,,CCN(CC)CC,[Cl-].[NH4+],test
US20130158020A1,CC(C)(C)OC(=O)N1CCSC(C(=O)O)C1.COC(=O)c1n[nH]c2ccc(N)cc12>>COC(=O)c1n[nH]c2ccc(NC(=O)C3CN(C(=O)OC(C)(C)C)CCS3)cc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070225377A1,CC(=O)N1CCC(c2ccc(OCC(=O)C(C)(C)C)c(C)c2)(c2ccc(OCC(O)CO)c(C)c2)CC1>>CC(=O)N1CCC(c2ccc(OCC(O)C(C)(C)C)c(C)c2)(c2ccc(OC[C@@H](O)CO)c(C)c2)CC1,,CO,,[BH4-].[Na+],,test
US05643950,COC(=O)COc1cccc(OCCC(c2ccccc2)(c2ccccc2)c2ccccc2)c1>>O=C(O)COc1cccc(OCCC(c2ccccc2)(c2ccccc2)c2ccccc2)c1,,CCOCC,,,,test
US20120064181A1,BrBr.COC(=O)c1ccc(N)c(NCC(C)(C)O)c1>>COC(=O)c1cc(Br)c(N)c(NCC(C)(C)O)c1,,ClCCl,,,,test
US20080318954A1,Cc1cc[nH]c(=O)n1.O=N[O-]>>O=c1nc(C=NO)cc[nH]1,,CC(=O)O,,Cl,,test
US05665754,COC(=O)N1C[C@@H](c2ccc(OC)c(OC3CCCC3)c2)[C@H](C(=O)O)C1.O=C(n1ccnc1)n1ccnc1>>COC(=O)N1C[C@@H](c2ccc(OC)c(OC3CCCC3)c2)[C@H](C(N)=O)C1,,ClCCl,,,,test
US20130158042A1,COCC1(C)CNC(=O)CN1Cc1ccccc1>>COCC1(C)CNCCN1Cc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110015175A1,Cc1ncn(-c2ccc(Nc3n[nH]c(C(CCCCCl)c4ccc(F)cc4)n3)cc2F)n1>>Cc1ncn(-c2ccc(Nc3nc4n(n3)CCCCC4c3ccc(F)cc3)cc2F)n1,,CC(C)=O,,[I-].[Na+],,test
US05399703,CCOC(=O)COc1ccc(C(=O)Nc2ccccc2Sc2ccccc2C#N)cc1.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)COc1ccc(C(=O)Nc2ccccc2S(=O)c2ccccc2C#N)cc1,,ClC(Cl)Cl,,,,test
US20070196270A1,CC(=O)Nc1cc(Cl)ccc1OCC(=O)N1CC2CN(C(=O)OC(C)(C)C)CC(C1)N2Cc1ccc(F)cc1>>CC(=O)Nc1cc(Cl)ccc1OCC(=O)N1CC2CNCC(C1)N2Cc1ccc(F)cc1,,CCO,,Cl,,test
US20140255381A1,O=C1CCN2CCC1CC2>>OC1CCN2CCC1CC2,,C1COCCO1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150376136A1,CCOC(=O)CC1CCCCC1.CI>>CCOC(=O)C(C)C1CCCCC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20020049192A1,Fc1ccc(Br)c(F)c1.O=C(C(Cl)(Cl)Cl)C(Cl)(Cl)Cl>>Fc1ccc(Br)c(F)c1Cl,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20150158851A1,COC(=O)C1(C)CCC(OC)(OC)CC1>>COC1(OC)CCC(C)(CO)CC1,,ClCCl,,,,test
US20060040918A1,CNC(=O)c1ccc(Oc2ccc3c(c2)CCNCC3)nc1.O=C1CCCC1>>CNC(=O)c1ccc(Oc2ccc3c(c2)CCN(C2CCCC2)CC3)nc1,,CC(=O)O,CO,,,test
US20110021531A1,NC(=O)c1ccccn1.O=C(CBr)c1ccc(Br)nc1>>Brc1ccc(-c2coc(-c3ccccn3)n2)cn1,,CCOC(C)=O,,O=C([O-])O.[Na+],,test
US20130225620A1,Clc1nccc(Nc2cc(C3CC3)n[nH]2)n1.NCc1ccc(F)c2[nH]ccc12>>Fc1ccc(CNc2nccc(Nc3cc(C4CC4)[nH]n3)n2)c2cc[nH]c12,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US04188395,CCOC(=O)/C=C(/C)N.CCOC(=O)CC(=O)COC(C)=O.O=Cc1ccccc1Cl>>CCOC(=O)C1=C(C)NC(COC(C)=O)=C(C(=O)OCC)C1c1ccccc1Cl,,CCO,,,,test
US05534515,Cc1cc2cnnc(Cl)c2n1CC(C)C.O=[N+]([O-])O>>Cc1c([N+](=O)[O-])c2cnnc(Cl)c2n1CC(C)C,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20160052884A1,BrCc1ccccc1.CC(C)(C)CC(O)C(=O)O>>CC(C)(C)CC(O)C(=O)OCc1ccccc1,,CO,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05084457,CCCN.O=c1[nH]c2ccccc2c(=O)o1>>CCCNC(=O)c1ccccc1N,,CC(C)O,,,,test
US20080207728A1,CNC(=O)c1cc(F)cc(B(O)O)c1.COC(=O)c1cc(Br)cc2c1OCCCC2>>CNC(=O)c1cc(F)cc(-c2cc3c(c(C(=O)OC)c2)OCCCC3)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20100240867A1,CCCCCCCCCCCCCCCCCCOCC(CI)(COCCCCCCCCCCCCCCCCCC)COCCCCCCCCCCCCCCCCCC.O=C1c2ccccc2-c2ccc(O)cc21>>CCCCCCCCCCCCCCCCCCOCC(COCCCCCCCCCCCCCCCCCC)(COCCCCCCCCCCCCCCCCCC)COc1ccc2c(c1)C(=O)c1ccccc1-2,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US05656573,COCCOc1c(S(C)(=O)=O)ccc(C(=O)C(C(=O)OC(C)(C)C)C(=O)C2CC2)c1Br>>COCCOc1c(S(C)(=O)=O)ccc(C(=O)CC(=O)C2CC2)c1Br,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100152165A1,COC(OC)c1ccc2c(n1)N(c1ccccc1)CCC2>>OCc1ccc2c(n1)N(c1ccccc1)CCC2,,C1CCOC1,,Cl,[Na+].[OH-],test
US20120238539A1,CC(C)(C)OC(=O)N1CCN(c2cccc(N)n2)CC1.ClC(Cl)(Cl)Cl.O=C1CCC(=O)N1Cl>>CC(C)(C)OC(=O)N1CCN(c2nc(N)c(Cl)cc2Cl)CC1,,ClCCl,,CCOC(C)=O,,test
US20040029874A1,CC(=O)Oc1ccccc1C(=O)Nc1ccc(Cl)cn1>>O=C(Nc1ccc(Cl)cn1)c1ccccc1O,,[Na+],[OH-],,,test
US20110281862A1,O=S(=O)(c1ccccc1)n1c2ccc(C#Cc3ccccc3)cc2c2cc(Cl)cnc21>>O=S(=O)(c1ccccc1)n1c2ccc(CCc3ccccc3)cc2c2cc(Cl)cnc21,[Pd],CCO,,,,test
US05049664,CCCCCCCCCCCCCCCC(OCc1ccccc1)C(CCCCCCCCCCCCCC)C(=O)OCC(=O)c1ccccc1>>CCCCCCCCCCCCCCCC(OCc1ccccc1)C(CCCCCCCCCCCCCC)C(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20110217300A1,C#CC[C@@H](NCCCNC(=O)OCc1ccccc1)c1nc2cccnc2c(=O)n1Nc1ccccc1.O=C(Cl)c1cccc(Cl)c1F>>C#CC[C@H](c1nc2cccnc2c(=O)n1Nc1ccccc1)N(CCCNC(=O)OCc1ccccc1)C(=O)c1cccc(Cl)c1F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080090854A1,CCOC(=O)C1(NC(=O)c2ccc3ccccc3c2O)CCC1.FC(F)(F)c1ccc(CCl)cn1>>CCOC(=O)C1(NC(=O)c2ccc3ccccc3c2OCc2ccc(C(F)(F)F)nc2)CCC1,,CN(C)C=O,,[I-].[Na+],O=C([O-])[O-].[Cs+].[Cs+],test
US20100048562A1,CC1(C)C(=O)c2ccccc2S1(=O)=O>>CC1(C)C(O)c2ccccc2S1(=O)=O,,CCO,,[BH4-].[Na+],,test
US20150283134A1,N#CC(=C1CCOCC1)c1ccc(Cl)cc1>>NCC(c1ccc(Cl)cc1)C1CCOCC1,[Ni],CO,,N,O,test
US20040132788A1,Cl.O=C(CBr)c1ccc2c(c1)N(C(=O)CCl)c1ccccc1S2>>O=C(CCl)c1ccc2c(c1)Nc1ccccc1S2,,CC(=O)O,,,,test
US20110052562A1,Nc1cc(Br)cnc1N.OB(O)c1ccncc1>>Nc1cc(-c2ccncc2)cnc1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US06469065B1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.OCC(CO)(CO)CO>>CC(C)(C)[Si](C)(C)OCC(CO)(CO)CO,,CCOC(C)=O,c1ccncc1,,,test
US20040242884A1,CNCC(O)c1ccc(OC)cc1.Cc1c(CCl)sc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12>>COc1ccc(C(O)CN(C)Cc2sc3c(=O)c(C(=O)NCc4ccc(Cl)cc4)cn(C)c3c2C)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,,test
US20080207698A1,C=CC(=O)N(CCN(CCc1ccc(O)c2[nH]c(=O)sc12)C(=O)OCc1ccccc1)C1CCCCC1.NCCc1cccc(F)c1F>>O=C(OCc1ccccc1)N(CCc1ccc(O)c2[nH]c(=O)sc12)CCN(C(=O)CCNCCc1cccc(F)c1F)C1CCCCC1,,CCO,,CCN(CC)CC,Cl,test
US20040138286A1,CCOC(=O)CCCCBr.CCOC(=O)CNCc1ccccc1>>CCOC(=O)CCCCN(CC(=O)OCC)Cc1ccccc1,,CC#N,,CCN(CC)CC,,test
US20080242666A1,NC(=O)c1ccccc1-n1cnnn1>>N#Cc1ccccc1-n1cnnn1,,O=P(Cl)(Cl)Cl,,CCN(CC)CC,,test
US05587224,CC(C)(C)c1ccc([I+]c2ccc(C(C)(C)C)cc2)cc1.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CC(C)(C)c1ccc([I+]c2ccc(C(C)(C)C)cc2)cc1.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,CO,,O,[Cl-].[Na+],test
US06384281B1,CI.CN(C)C(=O)[C@@H]1[C@H]2CC[C@H](C2)[C@@H]1c1ccc2sccc2c1>>Cc1cc2cc([C@H]3[C@@H]4CC[C@@H](C4)[C@H]3C(=O)N(C)C)ccc2s1,,C1CCOC1,,O,CC(C)[N-]C(C)C.[Li+],test
US03966966,COC(=O)COc1cccc(Cl)c1C.O=C(Cl)C1(C(=O)Cl)CCCC1>>COC(=O)COc1cc2c(c(Cl)c1C)C(=O)C1(CCCC1)C2=O,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20110086841A1,CCn1c(C2CC2)nc2c(N3CCOC[C@@H]3C)nc(-c3ccc([N+](=O)[O-])cc3)nc21>>CCn1c(C2CC2)nc2c(N3CCOC[C@@H]3C)nc(-c3ccc(N)cc3)nc21,[Pd],CO,,C1CCOC1,,test
US20130190330A1,O=S(Cl)Cl.O=[N+]([O-])c1cn(Cc2c(Cl)cccc2Cl)c(CO)n1>>O=[N+]([O-])c1cn(Cc2c(Cl)cccc2Cl)c(CCl)n1,,ClCCl,,CCN(CC)CC,,test
US20050213413A1,C=Cc1ccc([Mg]Br)cc1.O=C1C(c2ccccc2)=C(c2ccccc2)C(c2ccccc2)=C1c1ccccc1>>C=Cc1ccc(C2(O)C(c3ccccc3)=C(c3ccccc3)C(c3ccccc3)=C2c2ccccc2)cc1,,CCOCC,,,,test
US20060264433A1,CC(C)(C)OC(=O)NC1CNCC1c1ccc(Cl)cc1Cl.Clc1ccnc(Cl)n1>>CC(C)(C)OC(=O)NC1CN(c2ccnc(Cl)n2)CC1c1ccc(Cl)cc1Cl,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US09365588B2,CC(C)(C)OC(=O)N1CCC2(CC1)Oc1cc(Cl)ccc1-n1c(C(F)(F)F)ccc12.Cl>>Cl.FC(F)(F)c1ccc2n1-c1ccc(Cl)cc1OC21CCNCC1,,Cl,,C1COCCO1,,test
US07910363B1,CC(C)(C)OC(=O)NCCCCN(CCCC#N)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCCCN(CCCCN)C(=O)OC(C)(C)C,[Ni],CCO,,[NH4+].[OH-],,test
US20110144129A1,CCI.COC(=O)[C@H]1C=C[C@@H](n2c(C)ccc2C)C1>>CC[C@]1(C(=O)OC)C=C[C@@H](n2c(C)ccc2C)C1,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US06849644B2,CC(=O)N1CCc2ccc(S(=O)(=O)Cl)cc2C1.c1ccc2c(c1)CCN2>>CC(=O)N1CCc2ccc(S(=O)(=O)N3CCc4ccccc43)cc2C1,,ClCCCl,,c1ccncc1,,test
US20100121048A1,CC(C)(C)OC(=O)N1CCNC(Cc2ccccc2)C1.Cl.O=C(O)c1ncn(C2Cc3ccccc3C2)c1-c1ccccc1>>Cl.O=C(c1ncn(C2Cc3ccccc3C2)c1-c1ccccc1)N1CCNC[C@H]1Cc1ccccc1,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20090131677A1,O=C(O)C(=O)Cc1ccc(O)c(O)c1>>O=C(O)C(O)Cc1ccc(O)c(O)c1,,Cl,,,,test
US20150376167A1,BrP(Br)Br.COC(=O)c1cccc(CO)c1>>COC(=O)c1cccc(CBr)c1,,CCOCC,,O,O=C([O-])O.[Na+],test
US04395577,C=O.CC(N)=O.CCc1ccc([N+](=O)[O-])cc1>>CCc1ccc([N+](=O)[O-])cc1CNC(C)=O,,O=S(=O)(O)O,,,,test
US20040147561A1,CCOC(=O)c1cc(C(=O)CBr)c(=O)[nH]c1C.CNc1cc(C(N)=S)ccn1>>CCOC(=O)c1cc(-c2csc(-c3ccnc(NC)c3)n2)c(=O)[nH]c1C,,CCO,,,,test
US20080207736A1,COc1cccc(C(C#N)c2ccccc2)c1.Cc1ccc(S(=O)(=O)O[C@H]2CCN(Cc3ccccc3)C2)cc1>>COc1cccc(C(C#N)(c2ccccc2)[C@@H]2CCN(Cc3ccccc3)C2)c1,,C1CCOC1,,O,CC(C)(C)[O-].[K+],test
US20050245592A1,COc1c(C(C)=O)cc(Br)cc1N(C)C.C[Mg]Br>>COc1c(N(C)C)cc(Br)cc1C(C)(C)O,,CCOCC,CCOCC,[Cl-].[NH4+],,test
US20150344423A1,CC(NCC(C(F)(F)F)C(F)(F)F)=C1C(=O)OC(C)(C)OC1=O.CCO>>CCOC(=O)C=C(C)NCC(C(F)(F)F)C(F)(F)F,,CCO,,C,C[O-].[Na+],test
US06066642,CO.COc1ccc(O)c(C(C)=O)c1.O=CC=Cc1ccccc1>>Cc1ccc(O)c(C(=O)C=CC=Cc2ccccc2)c1,,O,,Cl,[Na+].[OH-],test
US20040198711A1,C=CC[C@H]1CC(=O)[C@@]2(C)CC[C@@H]3c4ccc(OCc5ccccc5)cc4CC[C@H]3[C@H]12>>C=CC[C@H]1C[C@H](O)[C@@]2(C)CC[C@@H]3c4ccc(OCc5ccccc5)cc4CC[C@H]3[C@H]12,O,C1CCOC1,,[BH4-].[Na+],[Cl-].[NH4+],test
US20080153837A1,Cc1cccc2[nH]c(-c3cccc4c3-c3ccccc3C4=NO)nc12>>Cc1cccc2[nH]c(-c3cccc4c3-c3ccccc3C4N)nc12,[Ni],C1CCOC1,CCO,,,test
US20070232594A1,CI.O=C(O)CN1Cc2ccccc2N(C(=O)c2ccc(N3CCCC3)cc2Cl)CC1=O>>COC(=O)CN1Cc2ccccc2N(C(=O)c2ccc(N3CCCC3)cc2Cl)CC1=O,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20090182025A1,BrBr.COc1ccc(-c2cc(NC(=O)[C@@H]3C[C@H]3C)sn2)cc1F>>COc1ccc(-c2nsc(NC(=O)[C@@H]3C[C@H]3C)c2Br)cc1F,,CCOC(C)=O,ClCCl,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20070213363A1,CN1CC(=O)Cc2c1cccc2[N+](=O)[O-]>>CN1CC(=O)Cc2c(N)cccc21,[Pd],CO,,,,test
US20120202867A1,CONC(C)[C@@H]1C[C@H]1c1c(Cl)sc(Cl)c1Cl.Cn1cc(C(=O)Cl)c(C(F)F)n1>>CON(C(=O)c1cn(C)nc1C(F)F)C(C)[C@@H]1C[C@H]1c1c(Cl)sc(Cl)c1Cl,,ClCCl,O,CCN(CC)CC,,test
US20150175594A1,O=C(O)C1=C(C(=O)Nc2sc3c(c2-c2nc(C4CC4)no2)CCC(C(F)(F)F)C3)CCC1.O=C1OC(=O)C2=C1CCCC2>>O=C(O)C1=C(C(=O)Nc2sc3c(c2-c2nc(C4CC4)no2)CCC(C(F)(F)F)C3)CCCC1,,CO,ClCCl,,,test
US20040087548A1,CC1=CC(=O)OC1=O.Nc1ccc([N+](=O)[O-])c2ccccc12>>CC1=CC(=O)N(c2ccc([N+](=O)[O-])c3ccccc23)C1=O,,CC(=O)O,,O=C([O-])[O-].[K+].[K+],,test
US20110136800A1,O=C(N1CCC[C@@H]2c3cc(O)ccc3C[C@@H]21)C(F)(F)F.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=C(N1CCC[C@@H]2c3cc(OS(=O)(=O)C(F)(F)F)ccc3C[C@@H]21)C(F)(F)F,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US20120295903A1,BrC1CCCC1.Cc1ccc([N+](=O)[O-])cc1O>>Cc1ccc([N+](=O)[O-])cc1OC1CCCC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080045537A1,CN[C@H]1CCCc2cccnc21.Cn1c(C=O)nc2cccc(N3CCN(C(=O)OC(C)(C)C)CC3)c21>>CN(Cc1nc2cccc(N3CCN(C(=O)OC(C)(C)C)CC3)c2n1C)[C@H]1CCCc2cccnc21,,CC(Cl)Cl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160237091A1,C=Cc1cc2cnn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c2cc1[N+](=O)[O-].OO>>O=[N+]([O-])c1cc2c(cnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1CCO,,C1CCOC1,,O,[Na+].[OH-],test
US20040054173A1,COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OCc1ccccc1.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)[C@@H]1C[C@@H](OS(=O)(=O)c2ccc(C)cc2)CN1C(=O)OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20070149579A1,CCC(O)(c1nnc(NCc2ccc3c(-c4ccc(F)cc4)cc(=O)oc3c2)o1)C(F)(F)F.CI>>CCC(O)(c1nnc(N(C)Cc2ccc3c(-c4ccc(F)cc4)cc(=O)oc3c2)o1)C(F)(F)F,,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US05387595,CCC1(C(C(=O)[O-])C(=O)[O-])CCCC(O)C1(CC)c1ccccc1>>O=C(O)C(C(=O)O)C1CCCC(O)C1c1ccccc1,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20070232583A1,CN.Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)Cl)c3)n2)n1>>CNS(=O)(=O)c1cccc(-c2cccc(-c3cc(-c4ccc(C(F)(F)F)cc4)cc(C)n3)n2)c1,,C1CCOC1,CCOC(C)=O,,,test
US20040077628A1,CC(C)(C)OC(=O)Nc1ccc2cc(CN3CCCCC3)ccc2c1>>Nc1ccc2cc(CN3CCCCC3)ccc2c1,,O=C(O)C(F)(F)F,,,,test
US20150299121A1,CCO.O=C(O)C1CCCC1>>CCOC(=O)C1CCCC1,,O,,O=S(=O)(O)O,,test
US06525083B2,C=CCOC(=O)[C@H](C)O.CCOC(=O)/N=N/C(=O)OCC.Cc1[nH]c2ccc(OC(F)(F)F)cc2c1Cc1cccc(O)c1.ClCCl.Oc1ccccc1>>COc1ccc(C(=O)n2c(C)c(Cc3cccc(O[C@@H](C)C(=O)O)c3)c3cc(OC(F)(F)F)ccc32)cc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150259295A1,COC(=O)C1(c2ccc(-c3ccc(-c4cnn(C)c4N)cc3)cc2)CC1.O=C=NCc1ccccc1>>Cn1ncc(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1NC(=O)NCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20100292210A1,CN1CC(c2ccccc2)Oc2nc(S(C)(=O)=O)ncc2C1=O.Oc1ccc(-n2ccnc2)cc1>>CN1CC(c2ccccc2)Oc2nc(Oc3ccc(-n4ccnc4)cc3)ncc2C1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050256158A1,CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(O)cc2)c2ccccc21.O=C1CCCN1CCCO>>CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(OCCCN3CCCC3=O)cc2)c2ccccc21,,c1ccccc1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05223498,N#Cc1ccc(N2CCOCC2)c(N)c1.S=C(Cl)Cl>>N#Cc1ccc(N2CCOCC2)c(N=C=S)c1,,C1COCCO1,O,,,test
US06114568,C=C(C)C.O=C(O)C1(NS(=O)(=O)c2ccc(Oc3ccc(F)cc3)cc2)CCCC1>>CC(C)(C)OC(=O)C1(NS(=O)(=O)c2ccc(Oc3ccc(F)cc3)cc2)CCCC1,,ClCCl,,O=S(=O)(O)O,,test
US20070082907A1,CCOC(=O)C(C)(C)Oc1ccc(Oc2ccc(C)c(C#N)c2)cc1C>>CCOC(=O)C(C)(C)Oc1ccc(Oc2ccc(C)c(CN)c2)cc1C,[Ni],N,,[H][H],,test
US20040106653A1,CCOC(=O)COc1cccc(S(=O)(=O)c2ccc(CCCN(Cc3ccccc3)C[C@H](O)c3cccc(Cl)c3)cc2)c1.Cl>>CCOC(=O)COc1cccc(S(=O)(=O)c2ccc(CCCNC[C@H](O)c3cccc(Cl)c3)cc2)c1.Cl,,CCOC(C)=O,,,,test
US20020193367A1,CC(C)CNc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-n3cncn3)c2)cc1C(F)(F)F>>CC(C)CNc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-n3cncn3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US04061656,CN(C)C=O.Cc1csc(C)c1Br>>Cc1csc(C)c1C=O,,CCCCCC,,CCOCC,[Li]CCCC,test
US06110956,[N-]=[N+]=NCCOc1cccc2c1OCCO2>>NCCOc1cccc2c1OCCO2,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20040110763A1,CC(C)n1nc(-c2c(-c3ccccc3)nn3ccc(N4CCC(O)CC4)cc23)ccc1=O.CI>>COC1CCN(c2ccn3nc(-c4ccccc4)c(-c4ccc(=O)n(C(C)C)n4)c3c2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20090137595A1,CC(C)(C)c1ccc(N)cc1.O=C(O)c1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1>>CC(C)(C)c1ccc(NC(=O)c2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)c2)cc1,CN(C)c1ccncc1,c1ccncc1,,CCN=C=NCCCN(C)C,Cl,test
US20100278833A1,COC(=O)c1sc(-n2cnc3ncccc32)cc1OCc1ccccc1C(F)(F)F.N>>NC(=O)c1sc(-n2cnc3ncccc32)cc1OCc1ccccc1C(F)(F)F,,CO,,,,test
US20100305096A1,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CNC3)n(C)c2n1.O=C(Cl)C1CC1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CC3CN(C(=O)C4CC4)C3)n(C)c2n1,,ClCCl,,CCN(CC)CC,,test
US20100197681A1,CCOC(=O)NC(=S)Nc1cccc(-c2ccsc2)n1.NO>>Nc1nc2cccc(-c3ccsc3)n2n1,,CCO,CO,CCN(C(C)C)C(C)C,Cl,test
US20150191452A1,CC(C)(C)OC(=O)N1CC[C@H](c2ccc(OCc3ccccc3)cc2)[C@@H](O)C1.Cl>>Cl.O[C@H]1CNCC[C@@H]1c1ccc(OCc2ccccc2)cc1,,C1COCCO1,,,,test
US20040204455A1,CC(C)(C)OC(=O)N1CCC(c2ccc(OCCCOCc3ccccc3F)cc2)C(N)C1.O=S(=O)(Cl)c1ccc2ccccc2c1>>CC(C)(C)OC(=O)N1CCC(c2ccc(OCCCOCc3ccccc3F)cc2)C(NS(=O)(=O)c2ccc3ccccc3c2)C1,,c1ccncc1,,,,test
US20090186886A1,Nc1nc2cc3c(cc2[n+]([O-])n1)CCC3.OO>>Nc1n[n+]([O-])c2cc3c(cc2[n+]1[O-])CCC3,,CC(=O)O,,N,,test
US20150274704A1,Cc1cnc(Nc2cnn(C)c2)nc1NC1CCC2(CC1)CCN(C(=O)OC(C)(C)C)CC2>>Cc1cnc(Nc2cnn(C)c2)nc1NC1CCC2(CCNCC2)CC1,,ClCCl,,CCOC(C)=O,Cl,test
US20150344473A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(-c3ncnc4c3cc(-c3ccc(N5CCN(CC(F)F)CC5)cc3)n4COCC[Si](C)(C)C)cc2C#N)CC1>>N#Cc1cc(-c2ncnc3[nH]c(-c4ccc(N5CCN(CC(F)F)CC5)cc4)cc23)ccc1OC1CCNCC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20090221642A1,Cc1ccc(NC2CCN(C3(C)CCN(C(=O)OC(C)(C)C)C3)CC2)c([N+](=O)[O-])c1>>Cc1ccc(NC2CCN(C3(C)CCN(C(=O)OC(C)(C)C)C3)CC2)c(N)c1,[Pd],CO,,,,test
US20060046978A1,CC(NC(=O)OC(C)(C)C)P(=O)(O)CC(Cc1ccccc1)C(=O)O.COC(=O)[C@H](C)N>>COC(=O)C(C)NC(=O)C(Cc1ccccc1)CP(=O)(O)C(C)NC(=O)OC(C)(C)C,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20090270369A1,Cc1n[nH]c(=O)o1.NC1CCOCC1>>Cc1n[nH]c(=O)n1C1CCOCC1,,CO,,,,test
US20050065188A1,CN1CCCC1.COC(=O)c1cc(I)cnc1Oc1ccc(F)cc1.ClCCl.O=C([O-])C(F)(F)F>>O=C(O)c1ccc(CNC(=O)c2cc(C(F)(F)F)cnc2Oc2ccc(F)cc2)cc1,[Cu]I,,,O,,test
US20120088767A1,COC(=O)c1cc(N2CCOCC2)cc2c1nc(C)n2Cc1cccc2ccccc12>>Cc1nc2c(C(=O)O)cc(N3CCOCC3)cc2n1Cc1cccc2ccccc12,,C1CCOC1,O,Cl,[Li+].[OH-],test
US04935438,Fc1cc(F)cc(Cn2ccnc2S)c1.O=C(O)CCl>>O=C(O)CSc1nccn1Cc1cc(F)cc(F)c1,,CN(C)C=O,O,Cl,[K+].[OH-],test
US20080045556A1,CC(C)(CO)Nc1nc(-c2ccc(Cl)c(F)c2)cs1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC1(C)COC(=O)N1c1nc(-c2ccc(Cl)c(F)c2)cs1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090176778A1,COC(=O)c1nc2c(NC(C)=O)cc(-c3ccoc3)cn2c1Cl>>CC(=O)Nc1cc(-c2ccoc2)cn2c(Cl)c(C(=O)O)nc12,,C1CCOC1,,[Na+].[OH-],,test
US06136823,CC(N)CO.Nc1cc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Cl)c32)c(F)cc1F>>CC(CO)Nc1c(F)cc2c(=O)c(C(=O)O)cn(-c3cc(N)c(F)cc3F)c2c1Cl,,c1ccncc1,,Cl,,test
US20120052757A1,CC(=O)Oc1cc(/C=C/c2ccccc2)cc(OC(C)=O)c1OC(C)=O>>Oc1cc(/C=C/c2ccccc2)cc(O)c1O,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05006522,BrCCCCCCN1CCCCCC1.Cl.O=C1Nc2ccccc2Nc2ccccc21>>Cl.O=C1Nc2ccccc2N(CCCCCCN2CCCCCC2)c2ccccc21,,CC#N,O,[Li]CCCC,,test
US20100179139A1,O=S(=O)(Cl)c1ccc(Br)cn1.O=S1(=O)CCNCC1>>O=S1(=O)CCN(S(=O)(=O)c2ccc(Br)cn2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04985419,CNCC(C)N1c2ccccc2Sc2ccc(C#N)cc21.OCCBr>>CC(CN(C)CCO)N1c2ccccc2Sc2ccc(C#N)cc21,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20120053173A1,CCC(=O)CC(=O)OC.COC(OC)N(C)C.NNc1cc(F)cc(F)c1>>COC(=O)c1cn(-c2cc(F)cc(F)c2)nc1C,,CCO,,Cl,,test
US20070003539A1,COC(=O)c1ccccc1S(=O)(=O)C1CCC1>>O=C(O)c1ccccc1S(=O)(=O)C1CCC1,,C1CCOC1,,[Li+].[OH-],,test
US06632919B1,CC(C)(C)C(=O)Cl.Nc1cccc(N)n1>>CC(C)(C)C(=O)Nc1cccc(N)n1,,C1COCCO1,,,,test
US20110212937A1,CNc1nc(Cl)nc2c1CCC2c1ccc(F)cc1.COc1cc(N)ccc1-n1cnc(Cl)c1>>CNc1nc(Nc2ccc(-n3cnc(Cl)c3)c(OC)c2)nc2c1CCC2c1ccc(F)cc1,,C1CCOC1,CC(=O)O,,,test
US07053099B1,N#Cc1c(N)cccc1F.Oc1ccccc1>>N#Cc1c(N)cccc1Oc1ccccc1,,CS(C)=O,,[H-].[Na+],,test
US20110092495A1,CC(C)(C)OC(=O)NC1CCN(CCOS(C)(=O)=O)CC1.COc1ccc2ccc(=O)n(CCN3CCC(NC(=O)OC(C)(C)C)CC3)c2c1.O=C1COc2ccc(Br)nc2N1>>CC(C)(C)OC(=O)NC1CCN(CCN2C(=O)COc3ncc(Br)cc32)CC1,,CO,ClCCl,[H-].[Na+],,test
US20040122063A1,CCOC(=O)[C@@H]1CC[C@@H](N=[N+]=[N-])[C@@H](NC(=O)OC(C)(C)C)C1>>CCOC(=O)[C@@H]1CC[C@@H](N)[C@@H](NC(=O)OC(C)(C)C)C1,[Pd],CCO,CCOC(C)=O,[H][H],,test
US20070010556A1,COC(=O)c1sc(-c2cccc(F)c2)cc1N.O=C=NC(=O)C(Cl)(Cl)Cl>>COC(=O)c1sc(-c2cccc(F)c2)cc1NC(N)=O,,C1CCOC1,CO,,,test
US20130045986A1,Nc1cc(Br)ccc1O.O=C(Cl)C1CCN(Cc2ccccc2)CC1>>O=C(Nc1cc(Br)ccc1O)C1CCN(Cc2ccccc2)CC1,,ClCCl,,c1ccncc1,,test
US20110070523A1,C=Cc1ccccc1-c1ccccc1.C=Cc1ccccc1C=C>>C=Cc1ccccc1-c1ccccc1.C=Cc1ccccc1C=C,,Cc1ccccc1,,,,test
US20140275482A1,CC(C)(C)OC(=O)NCCCOCCOCCOCCCNc1ccc(C(=O)c2ccc(OCCCNC(=O)CCOCCOCCOCCOCCNC(=O)CCN3C(=O)C=CC3=O)cc2)cc1>>NCCCOCCOCCOCCCNc1ccc(C(=O)c2ccc(OCCCNC(=O)CCOCCOCCOCCOCCNC(=O)CCN3C(=O)C=CC3=O)cc2)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US06333330B1,CCOc1ncc(S(=O)(=O)N2CCN(CC)CC2)cc1-c1nc2c(-c3ccco3)n(C)nc2c(=O)[nH]1>>CCOc1ncc(S(=O)(=O)N2CCN(CC)CC2)cc1-c1nc2c(C3CCCO3)n(C)nc2c(=O)[nH]1,[Pd],CCO,O,,,test
US20090318441A1,CCOC(OCC)c1cc2cnc(Cl)nc2n1C(CC)CC>>CCC(CC)n1c(C=O)cc2cnc(Cl)nc21,,C1COCCO1,,Cl,[Na+].[OH-],test
US20050245741A1,CNC(=O)c1ccc(OCc2ccc(OC)cc2)cc1O.C[C@@]1(COS(=O)(=O)c2cccc([N+](=O)[O-])c2)CO1>>CNC(=O)c1ccc(OCc2ccc(OC)cc2)cc1OC[C@]1(C)CO1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070106095A1,CC=C(CC)c1ccc(OCC(=O)C(C)(C)C)c(C(C)=O)c1>>CC=C(CC)c1ccc2oc(C(=O)OCC)c(C)c2c1,,CN(C)C=O,,C1CCC2=NCCCN2CC1,O,test
US20040152750A1,COC(=O)c1ccc(N(Cc2ccc(OC(F)(F)F)cc2)Cc2ccc(C3CCCCC3)cc2)cc1>>O=C(O)c1ccc(N(Cc2ccc(OC(F)(F)F)cc2)Cc2ccc(C3CCCCC3)cc2)cc1,,CCO,,CC(=O)O,[Na+].[OH-],test
US20100105667A1,COc1cc(OC)c(F)c(-c2ccc(Br)c3nccnc23)c1.N#C[Cu]>>COc1cc(OC)c(F)c(-c2ccc(C#N)c3nccnc23)c1,,CN1CCCC1=O,ClCCl,,,test
US04736031,COC(=O)C1(CCCN2CCN(c3ccccc3)CC2)Sc2ccccc2CCC1=O>>COC(=O)C1(CCCN2CCN(c3ccccc3)CC2)Sc2ccccc2CCC1O,,CO,,O,[BH4-].[Na+],test
US20130131017A1,CCOC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)c2cccn12>>O=S(=O)(Oc1ccc(CO)n2cccc12)C(F)(F)F,,CO,,O,[BH4-].[Na+],test
US05922882,CCN(CC)Cc1cc(CCCO)cc(-n2nc3ccccc3n2)c1O.OCCCc1ccc(O)c(-n2nc3ccccc3n2)c1>>OCCCc1cc(Cc2cc(CCCO)cc(-n3nc4ccccc4n3)c2O)c(O)c(-n2nc3ccccc3n2)c1,,Cc1ccccc1C,,CO,C[O-].[Na+],test
US20040116467A1,N#Cc1ccc(CC2(NC(=O)Nc3cc(Cl)cc(Cl)c3)CCCCC2=O)cc1>>N#Cc1ccc(CC23CCCC=C2N(c2cc(Cl)cc(Cl)c2)C(=O)N3)cc1,,Cc1ccccc1C,,O=C([O-])[O-].[K+].[K+],,test
US20120202867A1,CC(=O)[C@@H]1C[C@H]1c1c(Cl)sc(Cl)c1Cl.CON>>CON=C(C)[C@@H]1C[C@H]1c1c(Cl)sc(Cl)c1Cl,,CO,O,Cl,c1ccncc1,test
US04259492,CC(C)(C)c1cc(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1.CCCCNCCCC.ClP(Cl)Cl>>CCCCN(CCCC)p1oc2c(C(C)(C)C)cc(C(C)(C)C)cc2c2cc(C(C)(C)C)cc(C(C)(C)C)c2o1,,Cc1ccccc1,,CCN(CC)CC,,test
US20040186290A1,CI.O=C(Nc1nccs1)C(CC1CCCC1)c1ccc(S)nc1>>CSc1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140094462A1,C#CCN(C)C(=O)OC[C@H](N)c1ccccc1.O=C(Cl)CCl>>C#CCN(C)C(=O)OC[C@H](NC(=O)CCl)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20040106667A1,CS(=O)(=O)c1ccccc1S(=O)(=O)Nc1ccc2[nH]nc(-c3cccc([N+](=O)[O-])c3)c2c1>>CS(=O)(=O)c1ccccc1S(=O)(=O)Nc1ccc2[nH]nc(-c3cccc(N)c3)c2c1,[Fe],O,,CCO,Cl,test
US20080249301A1,COC(=O)c1sc(Nc2ccccc2[N+](=O)[O-])cc1O[Si](C(C)C)(C(C)C)C(C)C>>COC(=O)c1sc(Nc2ccccc2N)cc1O,[Pd],CCO,ClCCl,,,test
US05633279,COCCOCOc1c(C/C=C(\C)C=O)c(OC)c(C)c2c1C(=O)OC2>>COCCOCOc1c(C/C=C(\C)CO)c(OC)c(C)c2c1C(=O)OC2,,CO,,O,[BH4-].[Na+],test
US04470976,CC(=O)OC[C@H]1O[C@H](O[C@H]2[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](Sc3ccc(N)cc3)O[C@@H]2COC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>Nc1ccc(S[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)cc1,,CO,,,,test
US05750549,CSc1ccccc1CBr.O=S([O-])OO>>CS(=O)(=O)c1ccccc1CBr,,O,,CO,,test
US20090023929A1,CNc1cc(Cl)ccc1[N+](=O)[O-].Cc1cc(O)cc(C)c1[N+](=O)[O-]>>CNc1cc(Oc2cc(C)c([N+](=O)[O-])c(C)c2)ccc1[N+](=O)[O-],,CC(=O)N(C)C,,Cl,CC(C)(C)[O-].[K+],test
US07368458B2,NC1Cc2cc(-c3ccccc3)cnc2N(Cc2ccccc2)C1=O.O=S(=O)(Cl)c1ccccc1>>O=C1C(NS(=O)(=O)c2ccccc2)Cc2cc(-c3ccccc3)cnc2N1Cc1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20040122244A1,CC(=O)Oc1ccc(CC2=C(C)C(=O)C(C)=C(C)C2=O)cc1C(=O)O.Nc1cccnc1Cl>>CC(=O)Oc1ccc(CC2=C(C)C(=O)C(C)=C(C)C2=O)cc1C(=O)Nc1cccnc1Cl,,ClCCl,,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US06140320,C#CC(C)C.Nc1ccc(F)cc1C(=O)C(F)(F)F>>CC(C)C#CC(O)(c1cc(F)ccc1N)C(F)(F)F,,C1CCOC1,,[Li]CCCC,,test
US20090197863A1,COC(=O)c1cccc2nc(-c3ccc(CCN(C)C(=O)OCc4ccccc4)cc3)oc12.N>>CN(CCc1ccc(-c2nc3cccc(C(N)=O)c3o2)cc1)C(=O)OCc1ccccc1,,CO,,,,test
US20110065708A1,NCc1ccc2ncc(Br)cc2c1.Nc1ncc(Br)nc1Br>>Nc1ncc(Br)nc1NCc1ccc2ncc(Br)cc2c1,,CCO,,CCN(C(C)C)C(C)C,,test
US05514680,O=c1[nH]c2cc(Cl)c([N+](=O)[O-])cc2[nH]c1=O>>Nc1cc2[nH]c(=O)c(=O)[nH]c2cc1Cl,,CCO,,Cl[Sn]Cl,,test
US04891372,COc1cc([N+](=O)[O-])ccc1C(=O)NCCN1CCc2ccc([N+](=O)[O-])cc2CC1>>COc1cc(N)ccc1C(=O)NCCN1CCc2ccc(N)cc2CC1,,CCO,CO,,,test
US20130310427A1,CC1=C[C@@H](c2ncc(-c3ccc(-c4ccc5cc(-c6cnc([C@@H]7CCCN7C(=O)OC(C)(C)C)[nH]6)ccc5c4)cc3)[nH]2)N(C(=O)OC(C)(C)C)C1>>CC1=C[C@@H](c2ncc(-c3ccc(-c4ccc5cc(-c6cnc([C@@H]7CCCN7)[nH]6)ccc5c4)cc3)[nH]2)NC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05702887,CN(C)CCOC(=O)c1c2cc3ccccc3cc2nc2cccc(OCCN(C)C)c12>>CN(C)CCOc1cccc2nc3cc4ccccc4cc3c(C(=O)O)c12,,CO,,[Na+].[OH-],,test
US20090163592A1,NNC(=O)OCc1ccccc1.O=CC1CCCCC1>>O=C(NN=CC1CCCCC1)OCc1ccccc1,,CCO,,CC(=O)O,,test
US20090029976A1,COc1ccc(C=O)cc1Cl.O=C(OO)c1cccc(Cl)c1>>COc1ccc(O)cc1Cl,,ClCCl,,,,test
US20120238549A1,O=C1C=C2CCCc3cc(O)ccc3C2(Cc2ccccc2)CC1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>O=C1C=C2CCCc3cc(OS(=O)(=O)C(F)(F)F)ccc3C2(Cc2ccccc2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150274740A1,CCOC(=O)CC(=O)c1ccc(Cl)c(OC)c1.Nc1nc(-c2ccc(F)cc2)n[nH]1>>COc1cc(-c2cc(=O)n3nc(-c4ccc(F)cc4)nc3[nH]2)ccc1Cl,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120168732A1,COc1cccc(C(=O)NNC(=O)c2cccc(I)c2)c1>>COc1cccc(-c2nnc(-c3cccc(I)c3)o2)c1,,O=P(Cl)(Cl)Cl,,,,test
US20160000760A1,CI.CS(=O)(=O)c1ccc(-c2c(F)cc(N=C=S)cc2Cl)cc1.N#CN>>CSC(NC#N)Nc1cc(F)c(-c2ccc(S(C)(=O)=O)cc2)c(Cl)c1,,CO,,[Na],,test
US20080280917A1,BrP(Br)Br.O=c1ccc(Br)cn1CCO>>O=c1ccc(Br)cn1CCBr,,ClCCl,,,,test
US05693655,COC(=O)c1ccc2[nH]cc(CCCCN3CCC(c4c[nH]c5ccccc45)CC3)c2c1>>OCc1ccc2[nH]cc(CCCCN3CCC(c4c[nH]c5ccccc45)CC3)c2c1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20120208819A1,CC(C)Oc1cc(CNc2ncccc2C(=O)Cl)cc(-c2c[nH]c3ncc(C(=O)NC4CC4)cc23)c1.Nc1ccc(F)c(F)c1>>CC(C)Oc1cc(CNc2ncccc2C(=O)Nc2ccc(F)c(F)c2)cc(-c2c[nH]c3ncc(C(=O)NC4CC4)cc23)c1,,ClCCl,,,,test
US06414160B1,COc1cn(C(c2ccccc2)c2ccccc2)c(=O)o1.O=Cc1ccccc1>>COC(=O)C1C(c2ccccc2)OC(=O)N1C(c1ccccc1)c1ccccc1,,ClCCl,,O=C([O-])O.[Na+],,test
US06399629B1,COC(=O)[C@@H]1C[C@H](O)CN1C(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)[C@@H]1C[C@H](OS(=O)(=O)c2ccc(C)cc2)CN1C(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,,,test
US04282388,Fc1ccccc1CBr.O[C@H]1CCC[C@H]1O>>O[C@H]1CCC[C@H]1OCc1ccccc1F,,C1COCCO1,CO,[H][H],[H-].[Na+],test
US20160194284A1,O=C(Nc1ccc(Cl)cc1)Nc1cccc(-c2cccc(N3CCCC3)n2)c1.c1ccc2c(c1)CCNC2>>O=C(Nc1cccc(-c2cccc(N3CCCC3)n2)c1)N1CCc2ccccc2C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20070129364A1,COc1cc(N)ccc1Cl.O=C1CCC(=O)N1Br>>COc1cc(N)cc(Br)c1Cl,,C1CCOC1,,,,test
US20080207590A1,Nc1c(Cl)ncnc1Cl.c1ccc2c(c1)CCN2>>Nc1c(Cl)ncnc1N1CCc2ccccc21,,CCO,O,Cl,,test
US03947585,CCOC(=O)Cl.ClCCl.Clc1ccc2c(c1)C(c1ccccc1Cl)=NCc1cn[nH]c1-2>>CCOC(=O)n1cc2c(n1)-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2.Cl,,ClC(Cl)Cl,,c1ccncc1,,test
US20080242672A1,CS(=O)(=O)OCCn1ccc2c1nc(N)n1nc(-c3ccco3)nc21.Fc1ccc(F)c(N2CCNCC2)c1>>Nc1nc2c(ccn2CCN2CCN(c3cc(F)ccc3F)CC2)c2nc(-c3ccco3)nn12,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US05298627,COC(C)(C)OC.N#CCC(O)CC(O)CC(=O)N(c1ccccc1)c1ccccc1>>CC1(C)O[C@H](CC#N)C[C@H](CC(=O)N(c2ccccc2)c2ccccc2)O1,,CC(C)=O,,CS(=O)(=O)O,,test
US20150274767A1,CC(C)(C)[Si](C)(C)O[C@H]1C[C@H](c2ccc3c(N)ncnn23)OC1(CO)CO>>CC(C)(C)[Si](C)(C)O[C@H]1C[C@H](c2ccc3c(N)ncnn23)O[C@]1(C=O)CO,,CC#N,,,,test
US05385925,CCCCn1c(-c2ccc3nc(CCC)n(Cc4ccc(-c5ccccc5C(=O)OC(C)(C)C)cc4)c3c2)nc2ccccc21>>CCCCn1c(-c2ccc3nc(CCC)n(Cc4ccc(-c5ccccc5C(=O)O)cc4)c3c2)nc2ccccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040209921A1,CC(C)(C)OC(=O)N1CCC(NCc2ncccc2C(C)(C)c2ccc(F)cc2)CC1.Cc1cc(Cl)cnc1C=O>>Cc1cc(Cl)cnc1CN(Cc1ncccc1C(C)(C)c1ccc(F)cc1)C1CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130203818A1,COc1cc(-c2cc(C(F)(F)F)nn2C)ccc1NC(=O)c1ccccc1Cl>>Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)c2ccccc2Cl)c(O)c1,,ClCCl,,BrB(Br)Br,,test
US20120115811A1,CC1(C)OB(c2ccnn2C2CCCCO2)OC1(C)C.COc1ncc(Br)cc1N>>COc1ncc(-c2ccnn2C2CCCCO2)cc1N,,O,,COCCOC,,test
US05455258,BrCc1ccccc1.COc1ccc(S(=O)(=O)N[C@H](CC(C)C)C(=O)OC(C)(C)C)cc1>>COc1ccc(S(=O)(=O)N(Cc2ccccc2)[C@H](CC(C)C)C(=O)OC(C)(C)C)cc1,,CN(C)C=O,,[H-].[Na+],,test
US06337342B1,CCOC(=O)n1cc(-n2c(-c3cn(C)c4ccccc34)c[nH]c2=O)c2ccccc21>>Cn1cc(-c2c[nH]c(=O)n2-c2c[nH]c3ccccc23)c2ccccc21,,C1CCOC1,,CN,,test
US20120122972A1,CC(C)(C)[Si](OCCCCC#CCOC1CCCCO1)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](OCCCCC#CCO)(c1ccccc1)c1ccccc1,,CCOCC,,,,test
US20040053908A1,Nc1cc(Oc2ccc3[nH]ccc3c2)ccn1.O=C(NC1CC1)Oc1ccccc1>>Nc1cc(Oc2ccc3c(ccn3C(=O)NC3CC3)c2)ccn1,,CN(C)C=O,,O,[H-].[Na+],test
US20040087601A1,Cc1cc(Cl)nc(Cl)n1.Clc1ccc(CBr)cc1>>Clc1ccc(CCc2cc(Cl)nc(Cl)n2)cc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20140378686A1,CC(=O)N1CCc2[nH]nc(-c3ccc(F)cc3)c2C1.O[C@H]1CCc2ccccc21>>CC(=O)N1CCc2c(c(-c3ccc(F)cc3)nn2[C@@H]2CCc3ccccc32)C1,,Cc1ccccc1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US04279902,C(CC1CO1)C1CO1.CC1(C)OCC(CO)O1.O>>CC1(C)OCC(COCC2CCC(CO)O2)O1,,O,,[H-].[Na+],,test
US20050131012A1,FC(F)(F)Oc1cccc(SSc2cccc(OC(F)(F)F)c2)c1.NC(=O)c1cc2ncccc2[nH]1>>NC(=O)c1[nH]c2cccnc2c1Sc1cccc(OC(F)(F)F)c1,,CN(C)C=O,,,,test
US20060094750A1,NCC1(O)CCCC1.O=[N+]([O-])c1cc(Br)ccc1Br>>O=[N+]([O-])c1cc(Br)ccc1NCC1(O)CCCC1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,Cl,test
US20080051395A1,Nc1cccc(-c2nn3cccc(F)c3c2-c2ccnc(Cl)n2)c1.O=C(Cl)c1c(F)cccc1F>>O=C(Nc1cccc(-c2nn3cccc(F)c3c2-c2ccnc(Cl)n2)c1)c1c(F)cccc1F,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20150291563A1,CC(C)(C)OC(=O)N1CCCN(c2ccc(C3CC(C(O)(C(F)(F)F)C(F)(F)F)=NN3c3ccccc3Cl)cc2)CC1.Cl>>Cl.OC(C1=NN(c2ccccc2Cl)C(c2ccc(N3CCCNCC3)cc2)C1)(C(F)(F)F)C(F)(F)F,,CCOC(C)=O,,,,test
US20130158003A1,NC=O.O=C(c1ccccc1)C(O)c1ccccc1>>c1ccc(-c2ncoc2-c2ccccc2)cc1,,Cc1ccccc1C,,O=S(=O)(O)O,,test
US20030203917A1,CC1(C)C2CC[C@]1(CS(=O)(=O)O)C(=O)C2.CC1(C)C2CC[C@]1(CS(=O)(=O)O)C(=O)C2.CCCCCCCN1CCN(C(=O)OC(C)(C)C)C[C@@H]1CO.ClCCl.O=C(O)[C@H]1CNCCN1>>CCCCCCCN1CCN(CC(O)c2ccnc3ccc(OC)cc23)C[C@@H]1CO,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060111375A1,COc1cc2nccc(Cl)c2cc1OC.Clc1ccccc1Cl.Oc1ccc2ncccc2c1I>>COc1cc2nccc(Oc3ccc4ncccc4c3Cl)c2cc1OC,CN(C)c1ccncc1,,,,,test
US20020022631A1,CC[Mg]Br.CON(C)C(=O)[C@@H](Cc1ccncc1)NC(=O)OC(C)(C)C>>CCC(=O)[C@@H](Cc1ccncc1)NC(=O)OC(C)(C)C,,C1CCOC1,CCOCC,O,,test
US20060142585A1,N#C[C@@H]1C[C@H](F)CN1.O=C(Cl)CCl>>N#C[C@@H]1C[C@H](F)CN1C(=O)CCl,,ClCCl,O,CCN(CC)CC,Cc1ccc(S(=O)(=O)O)cc1,test
US04814329,C#CCBr.S=c1[nH]c2ccc(Cc3ccccc3)cc2[nH]1>>C#CCSc1nc2ccc(Cc3ccccc3)cc2[nH]1,,CCO,,,,test
US20050101614A1,CC(=O)OC(C)=O.Cc1ccnc(-c2ccc(Cl)cc2Cl)c1[N+](=O)[O-]>>CC(=O)Nc1c(C)ccnc1-c1ccc(Cl)cc1Cl,[Fe],Cc1ccccc1,O,CCO,Cl,test
US20130089520A1,CC1(S(N)(=O)=O)CC1.COc1ccc2c(OC3CC4C(=O)NCCCCC=CC5CC5(C(=O)O)N(C)C(=O)C4C3)cc(-c3nc(C(C)C)cs3)nc2c1C>>COc1ccc2c(OC3CC4C(=O)NC5(C(=O)NS(=O)(=O)C6(C)CC6)CC5C=CCCCCN(C)C(=O)C4C3)cc(-c3nc(C(C)C)cs3)nc2c1C,,C1CCOC1,,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US06265415B1,CCOC(=O)c1c(C)nc2c(N)cc(Br)cn12.Cc1cc(F)cc(C)c1CBr>>CCOC(=O)c1c(C)nc2c(NCc3c(C)cc(F)cc3C)cc(Br)cn12,,CC(C)=O,,[I-].[Na+],,test
US20080261920A1,BrCCBr.NC1=NC(c2ccc(F)cc2F)CO1>>NC1=NC(c2ccc(F)c(Br)c2F)CO1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20090082343A1,CN(Cc1ccccc1)c1cc(C#N)ccn1.COC(=O)c1ccccc1S>>CN(Cc1ccccc1)c1cc(-c2nc(=O)c3ccccc3s2)ccn1,,Cc1ccccc1,,CCN(CC)CC,,test
US20020169200A1,CO.Cc1cc(OCCOCc2ccccc2)ccc1[N+](=O)[O-]>>c1ccc(COCCOc2ccc3[nH]ccc3c2)cc1,[Pd],CCOC(C)=O,CO,C1CCNC1,,test
US20160214977A1,CCn1c2ccccc2c2nc(CO)ccc21>>CCn1c2ccccc2c2nc(C=O)ccc21,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20090054352A1,COC(=O)c1ccc(-c2cccn(CCN(C)C)c2=O)cc1>>COC(=O)c1ccc(C2CCCN(CCN(C)C)C2=O)cc1,O=[Pt],CC(=O)O,,[H][H],,test
US20160145268A1,BrBr.Cc1ccc([N+](=O)[O-])c(O)c1>>Cc1cc(O)c([N+](=O)[O-])cc1Br,,CC(=O)O,,,,test
US20130221278A1,CCSC(=NC)c1ccccc1C.NNC(=O)c1ccccc1>>Cc1ccccc1-c1nnc(-c2ccccc2)n1C,,CCCCO,,,,test
US05840732,CCCC=C1SC(=O)N(CCCCSc2cccc3nc(C)cn23)C1=O.Cl>>CCCC=C1SC(=O)N(CCCCSc2cccc3nc(C)cn23)C1=O.Cl,,CO,,,,test
US05696113,C1CNCCNC1.COc1ccc2c(Cl)noc2c1>>COc1ccc2c(N3CCCNCC3)noc2c1,,CCOC(C)=O,,,,test
US20070244173A1,COCCOS(=O)(=O)C(F)(F)F.Cc1nc2c3c(ccc2n1C)[C@@H](O)[C@H](OC(=O)C(C)(C)C)[C@@H](c1ccccc1)O3>>COCCO[C@@H]1c2ccc3c(nc(C)n3C)c2O[C@H](c2ccccc2)[C@H]1OC(=O)C(C)(C)C,,C1CCOC1,,,,test
US05597820,COC(=O)c1ccc(N)c(O)c1.O=C(Cl)CCl>>COC(=O)c1ccc2c(c1)OCC(=O)N2,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110319425A1,CC(C)C(=O)Cl.c1ccc(Nc2nc3c(s2)CCc2[nH]ncc2-3)nc1>>CC(C)C(=O)n1ncc2c1CCc1sc(Nc3ccccn3)nc1-2,,C1CCOC1,,,,test
US20030105099A1,CCC(NC(=O)OC(C)(C)C)C(=O)c1nc2ccccc2o1>>CCC(N)C(=O)c1nc2ccccc2o1,,ClCCl,,Cl,,test
US20150152046A1,CCOC(=O)CNC1=CC(=O)CCC1.O=C(Cl)C(=O)Cl>>CCOC(=O)CNC1=CC(Cl)=CCC1,CN(C)C=O,ClCCl,,,,test
US20080275035A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.NC(=O)c1ccc(OC(F)(F)F)cc1>>NC(=S)c1ccc(OC(F)(F)F)cc1,,COCCOC,,,,test
US07199105B2,C1CO1.CSC1OC(C(NC(=O)C2CC(CCC(F)F)CN2)C(C)C)C(O)C(O)C1O>>CSC1OC(C(NC(=O)C2CC(CCC(F)F)CN2CCO)C(C)C)C(O)C(O)C1O,,CO,,,,test
US05753664,CN(C)C(=O)Cl.Cc1cccc2nc(SCc3ccc(C(=O)c4ccc(O)cc4)cc3)n(C)c(=O)c12>>Cc1cccc2nc(SCc3ccc(C(=O)c4ccc(OC(=O)N(C)C)cc4)cc3)n(C)c(=O)c12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150322056A1,Cc1nccc(Cl)n1.Ic1cc[nH]n1>>Cc1nccc(-n2ccc(I)n2)n1,,CS(C)=O,,[H-].[Na+],,test
US20110082135A1,O=P(Cl)(Cl)Cl.O=c1[nH]c2ccc3nnc(C(F)F)n3c2cc1-c1ccccc1>>FC(F)c1nnc2ccc3nc(Cl)c(-c4ccccc4)cc3n12,,CC#N,,,,test
US20130137661A1,CC(C)(C)OC(=O)N[C@@H](Cn1c(=O)c(N)cn(Cc2c(F)cccc2F)c1=O)c1ccccc1.O=C(Cl)CCl>>CC(C)(C)OC(=O)N[C@@H](Cn1c(=O)c(NC(=O)CCl)cn(Cc2c(F)cccc2F)c1=O)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20070191309A1,COc1ccc2c(c1)C(=O)N1CCC(OCCCCCCCCCOC3CCN4C(=O)c5cc(OC)ccc5N(C(=O)OC(C)(C)C)[C@@H](OC5CCCCO5)[C@H]34)[C@H]1[C@H](OC1CCCCO1)N2C(=O)OC(C)(C)C>>COc1ccc2c(c1)C(=O)N1CCC(OCCCCCCCCCOC3CCN4C(=O)c5cc(OC)ccc5N=C[C@@H]34)[C@@H]1C=N2,,CO,ClC(Cl)Cl,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20090239854A1,C=Cc1ccc(=O)n(C2CC2)c1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>Cc1ccc2c(c1)c1c(n2CCc2ccc(=O)n(C3CC3)c2)CCN(C)C1,,CN1CCCC1=O,,[K+].[OH-],,test
US06225306B1,O=C(O)[C@@H]1C[C@@H](O)CN1.O=c1[nH]c2ccccc2c(=O)o1>>O=C1Nc2ccccc2C(=O)N2C[C@H](O)C[C@@H]12,,CS(C)=O,,,,test
US20030166639A1,Cc1cc(-c2cccc(C(=O)CC(=O)Nc3cc(C(F)(F)F)c(OCC(F)(F)F)cc3NC(=O)OC(C)(C)C)c2)cc(COC2CCCCO2)n1>>Cc1cc(-c2cccc(C3=Nc4cc(OCC(F)(F)F)c(C(F)(F)F)cc4NC(=O)C3)c2)cc(CO)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130039906A1,Fc1cccc(-c2nn(C3CCCCO3)c3cnc(-c4cccnc4)cc23)n1.O=C(NC1CCNCC1)OCc1ccccc1>>NC1CCN(c2cccc(-c3n[nH]c4cnc(-c5cccnc5)cc34)n2)CC1,,CS(C)=O,,O,,test
US20110086854A1,COC(=O)c1ccc(NC(=O)N2C[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)cc1>>CC(C)(C)C[C@@H]1CN(C(=O)Nc2ccc(C(=O)O)cc2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F,,C1CCOC1,CO,[Li+].[OH-],,test
US20070191334A1,C=CCOc1cc(C(=O)N(C)C)cn2cc(C)nc12>>C=CCc1c(C(=O)N(C)C)cn2cc(C)nc2c1O,,CCOCC,,CC(C)=O,,test
US20100048610A1,CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1Oc1ccc([N+](=O)[O-])c(CO)c1.O=C=Nc1ccccc1>>CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)ccc1Oc1ccc([N+](=O)[O-])c(COC(=O)Nc2ccccc2)c1,,ClCCl,O,Cl,c1ccncc1,test
US04129654,CI.O=c1[nH]c(=O)n(C2CCCCC2)c2nocc12>>Cn1c(=O)c2conc2n(C2CCCCC2)c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05834506,CNOC.O=C(O)CCc1ccc(OCc2ccccc2)cc1>>CON(C)C(=O)CCc1ccc(OCc2ccccc2)cc1,,O=S(Cl)Cl,,Cl,c1ccncc1,test
US04097587,CCC1(C)CC2(NC(=O)NC2=O)C(C)C(C)(CC)N1.CI>>CCC1(C)CC2(NC(=O)N(C)C2=O)C(C)C(C)(CC)N1,,CN(C)C=O,,[K],,test
US05656629,CCc1nn(C2CCCC2)c(N)c1C#N.O=C(O)Cc1ccncc1>>CCc1nn(C2CCCC2)c(NC(=O)Cc2ccncc2)c1C#N,,CN(C)C=O,,Cl,[H-].[Na+],test
US04478749,COP(=O)([O-])N1CC(NC(=O)OCc2ccccc2)C1=O.[K]>>COP(=O)([O-])N1C[C@H](N)C1=O.[K],[Pd],CCO,,[H][H],,test
US04319913,CCCCCCCCP(=O)(Cl)Cl.c1ccc(CNc2ccccc2)cc1>>CCCCCCCCP1(=O)c2ccccc2CN1c1ccccc1,,ClCCl,,,,test
US05244910,NCCCN.O=C(OCc1ccccc1)ON1C(=O)CCC1=O>>NCCCNC(=O)OCc1ccccc1,,ClC(Cl)Cl,,,,test
US20100035942A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(CO)c(N)c1>>Cc1ccc(CO)c(NC(=O)OC(C)(C)C)c1,,C1CCOC1,,,,test
US20150307480A1,CC(N)=CC#N.CC1=CC(=O)OC(C)(C)O1>>Cc1cc(=O)c(C#N)c(C)[nH]1,,CCOC(C)=O,,,,test
US20070254931A1,CCOC(=O)/C=C/c1sc(NC(C)=O)nc1CCc1ccc(N/C(=N/C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)cc1>>CC(=O)Nc1nc(CCc2ccc(N/C(=N/C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)cc2)c(/C=C/C(=O)O)s1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20140093513A1,Cc1ncc(C#N)c(N)n1>>Cc1ncc(CN)c(N)n1,[Ni],CO,,N,[H][H],test
US20070167441A1,COc1cccc2c(=O)c3c(O)cc(O)cc3oc12.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1cccc2c(=O)c3c(O)cc(OS(=O)(=O)C(F)(F)F)cc3oc12,,ClCCl,,c1ccncc1,,test
US20140221344A1,ClCc1ccc(-c2ncccc2Cl)nn1.[N-]=[N+]=[N-]>>[N-]=[N+]=NCc1ccc(-c2ncccc2Cl)nn1,,CN(C)C=O,,O,,test
US20110098324A1,CC(N)c1ccc(Cl)cc1.CCOC(=O)CNC(=O)c1c(O)c(C(=O)OC)c(O)n(Cc2ccccc2Cl)c1=O>>CC(NC(=O)c1c(O)c(C(=O)NCC(=O)O)c(=O)n(Cc2ccccc2Cl)c1O)c1ccc(Cl)cc1,,ClC(Cl)Cl,,,,test
US05444074,CSCc1cc(C(C)(C)C)cc(Cl)c1N>>Cc1cc(C(C)(C)C)cc(Cl)c1N,[Ni],CO,,,,test
US20040116709A1,C[C@H](O)C(=O)Nc1ccccn1>>C[C@H](O)CNc1ccccn1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20090105474A1,CC(C)(C)OC(=O)c1ccc(-c2cccc(F)c2)cc1Nc1ccc(F)cc1>>O=C(O)c1ccc(-c2cccc(F)c2)cc1Nc1ccc(F)cc1,,O=C(O)C(F)(F)F,,,,test
US20070197526A1,ClCCCN1CCCC1.Oc1ccc(-n2cc3ccccc3n2)cc1>>c1ccc2nn(-c3ccc(OCCCN4CCCC4)cc3)cc2c1,,CN(C)C=O,,[H-].[Na+],,test
US20070179122A1,O=C1COCCN1c1ccc([N+](=O)[O-])c(C(F)F)c1>>Nc1ccc(N2CCOCC2=O)cc1C(F)F,[Pd],CC(=O)O,CCOC(C)=O,,,test
US06177067B1,CC(C)(CO)CO.CCCCCCCCCCCCCCCCCCBr>>CCCCCCCCCCCCCCCCCCOCC(C)(C)CO,,O,,CN(C)C=O,[H-].[Na+],test
US20110053940A1,Cc1ccc(C(=O)O)cc1Br.O=C1CCC(=O)N1I>>Cc1c(Br)cc(C(=O)O)cc1I,,O=S(=O)(O)O,,,,test
US20120252818A1,CC(=O)OC(C)=O.CCOc1nc(N(Cc2ccc(OC)cc2)Cc2ccc(OC)cc2)nc(OCC)c1Sc1nc(N)cc(N)n1>>CCOc1nc(N(Cc2ccc(OC)cc2)Cc2ccc(OC)cc2)nc(OCC)c1Sc1nc(NC(C)=O)cc(NC(C)=O)n1,CN(C)c1ccncc1,CC(=O)OC(C)=O,,,,test
US20090291917A1,IC1CCCC1.N#Cc1ccc(Oc2ccc3c(c2)COB3O)c(O)c1>>N#Cc1ccc(Oc2ccc3c(c2)COB3O)c(OC2CCCC2)c1,,O,,CN(C)C=O,[H-].[Na+],test
US05457099,O=c1cc(CCBr)c2ccccc2[nH]1.c1ccc2c(C3CCNCC3)c[nH]c2c1>>O=c1cc(CCN2CCC(c3c[nH]c4ccccc34)CC2)c2ccccc2[nH]1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20010029239A1,C#CCBr.COC=C(Oc1cccc(OC(=COC)C(=O)OC)c1C(=O)O)C(=O)OC>>C#CCOC(=O)c1c(OC(=COC)C(=O)OC)cccc1OC(=COC)C(=O)OC,,CC#N,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US20040204455A1,CCOC(COc1ccc(C)cc1)OCC>>Cc1ccc2occc2c1,,c1ccccc1,,,,test
US20100190764A1,COC(=O)C1=CCCN(C2CCC3(Cc4cc(F)ccc4Cc4ccccc43)C2)C1>>O=C(O)C1=CCCN(C2CCC3(Cc4cc(F)ccc4Cc4ccccc43)C2)C1,,CO,O,[Li+].[OH-],,test
US20090093497A1,COC(=O)C1CCN(c2ccc(NC(=O)c3nc(-c4ccccc4)oc3C(F)(F)F)cc2)CC1>>O=C(Nc1ccc(N2CCC(C(=O)O)CC2)cc1)c1nc(-c2ccccc2)oc1C(F)(F)F,,C1CCOC1,CO,[Na+].[OH-],,test
US20080185577A1,Nc1ccc(-c2c(F)c(F)c(F)c(F)c2F)cc1.[Li]CCCCCCCC>>CCCCCCCCc1c(F)c(F)c(-c2ccc(N)cc2)c(F)c1F,,CCOCC,,Cl,,test
US05460669,N=C(N)N.O=[N+]([O-])Nc1nonc1[N+](=O)[O-]>>NC(N)=[NH2+].O=[N+]([O-])Nc1nonc1[N+](=O)[O-],,CO,,,,test
US20130225524A1,COc1ncc(B(O)O)c(OC)n1.NC(=O)c1cnc2cc(Br)ccc2c1Cl>>COc1ncc(-c2ccc3c(Cl)c(C(N)=O)cnc3c2)c(OC)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20020082268A1,Nc1ccccc1C(=O)O.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=c1[nH]c2ccccc2c(=O)o1,,C1CCOC1,,,,test
US20160257690A1,Cc1cccc(-c2c[nH]c(C(C)C)n2)c1.O=C1CCC(=O)N1Br>>Cc1cccc(-c2nc(C(C)C)[nH]c2Br)c1,,CC#N,,,,test
US20130023514A1,CCOC(=O)[C@@H]1CC[C@@H](N(Cc2ccccc2)Cc2ccccc2)CC1.NN>>NNC(=O)[C@@H]1CC[C@@H](N(Cc2ccccc2)Cc2ccccc2)CC1,,CCO,,O,,test
US20130137853A1,COC(=O)CN.NC(=O)CC[C@H](N)C(=O)O>>NCC(=O)N[C@@H](CCC(N)=O)C(=O)O,,O,,Cl,,test
US20020143034A1,CC(C)=O.CC1(C)OC[C@H](Cc2ccc(OS(=O)(=O)C(F)(F)F)cc2)N1Cc1ccccc1.O=C=O.Sc1ccccc1.[Li]CCCC>>CC(C)(C)OC(=O)N1[C@@H](Cc2ccc(Sc3ccccc3)cc2)COC1(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,O,[Cl-].[Li+],,test
US20120264734A1,Cc1cc(C)c(CNC(=O)c2cc(Br)cc(NC3CCCC3)c2C)c(=O)[nH]1.OB(O)c1ccc(CN2CCOCC2)cc1>>Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(CN4CCOCC4)cc3)cc(NC3CCCC3)c2C)c(=O)[nH]1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,ClCCl,O=C([O-])[O-].[Na+].[Na+],test
US20090318473A1,CCOC(=O)c1ccc(-c2c(OC)cccc2OC)c(-c2ccc(Cl)c(O)c2)n1.CN1CCC(O)C1>>CCOC(=O)c1ccc(-c2c(OC)cccc2OC)c(-c2ccc(Cl)c(OC3CCN(C)C3)c2)n1,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140018319A1,C[C@@H]1CO1.N#Cc1n[nH]c2ccc([N+](=O)[O-])cc12>>C[C@@H](O)Cn1nc(C#N)c2cc([N+](=O)[O-])ccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150361070A1,C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1cn(COCC[Si](C)(C)C)cn1>>C[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1c[nH]cn1,O=C(O)C(F)(F)F,ClCCl,,,,test
US05232940,CSc1c(C(F)(F)F)nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1N.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1c(C(F)(F)F)nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1N,,ClC(Cl)Cl,ClCCl,,,test
US20050267105A1,Cl.N#Cc1ccc(F)cc1OCc1ccccc1>>Cl.NCc1ccc(F)cc1O,[Pd],CCO,CCOC(C)=O,,,test
US20080103123A1,CN(Cc1ccc(Cl)nc1)C1CCN(C(=O)OC(C)(C)C)CC1.N#Cc1ccc(B(O)O)cc1>>CN(Cc1ccc(-c2ccc(C#N)cc2)nc1)C1CCN(C(=O)OC(C)(C)C)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US06239131B1,Nc1ccccc1[N+](=O)[O-].O=[N+]([O-])c1ccccc1F>>O=[N+]([O-])c1ccccc1Nc1ccccc1F,[Cu],Cc1ccccc1C,,O=C([O-])[O-].[K+].[K+],,test
US20160244554A1,CNCCNC.O=C(O)Cc1ccsc1>>CN(C)CCNC(=O)Cc1ccsc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20110152245A1,CC(C)(C)OC(=O)N1CCCC1Cc1ccc(NC(=O)c2ccc(Cl)cc2)cc1.Cl>>Cl.O=C(Nc1ccc(CC2CCCN2)cc1)c1ccc(Cl)cc1,,C1CCOC1,C1COCCO1,,,test
US20100173888A1,CC(C)(C)OC(=O)N[C@H]1CCC[C@@H](N)C1.O=C(O)c1ccc(-c2cccc(F)c2)nc1>>CC(C)(C)OC(=O)N[C@H]1CCC[C@@H](NC(=O)c2ccc(-c3cccc(F)c3)nc2)C1,,CN(C)C=O,,,,test
US20030060466A1,Cc1nc(Br)c([N+](=O)[O-])c(=O)[nH]1.OC1(c2ccccc2)CCNCC1>>Cc1nc(N2CCC(O)(c3ccccc3)CC2)c([N+](=O)[O-])c(=O)[nH]1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05910504,O=[N+]([O-])c1ccc(F)c(F)c1.c1c[nH]nn1>>O=[N+]([O-])c1ccc(-n2ccnn2)c(F)c1,,CS(C)=O,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20120184735A1,COc1c(C(O)C(F)(F)F)cc(C(C)(C)C)cc1[N+](=O)[O-]>>COc1c(N)cc(C(C)(C)C)cc1C(O)C(F)(F)F,[Fe],CCO,O,[Cl-].[NH4+],,test
US06307056B1,COC(=O)c1ccc(B(O)O)cc1.COc1cc[nH]c1/C=C1\C(=O)Nc2ccc([N+](=O)[O-])c(Br)c21>>COC(=O)c1ccc(-c2c([N+](=O)[O-])ccc3c2/C(=C/c2[nH]ccc2OC)C(=O)N3)cc1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20140194430A1,CNCC(O)c1ccccc1.Clc1ccc2ncc(-c3cc4cnccc4o3)n2n1>>CN(CC(O)c1ccccc1)c1ccc2ncc(-c3cc4cnccc4o3)n2n1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US05646173,CC(=O)NCCN.COc1ccc2c(c1)C(=O)C(CC=O)C2>>COc1ccc2c(c1)-c1c(ccn1CCNC(C)=O)C2,,Cc1ccccc1,,,,test
US20100120714A1,COC(=O)NCc1cc(C#C[Si](C)(C)C)ccc1Cl>>C#Cc1ccc(Cl)c(CNC(=O)OC)c1,,CO,,[K+].[OH-],,test
US20130338066A1,COc1ccc(CNCc2ccc(OC)cc2OC)c(OC)c1.O=S(=O)(Cl)Cc1cccc(Br)c1>>COc1ccc(CN(Cc2ccc(OC)cc2OC)S(=O)(=O)Cc2cccc(Br)c2)c(OC)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080200448A1,CCOC(=O)c1ccc(O)nc1C.O=C1CCC(=O)N1Cl>>CCOC(=O)c1cc(Cl)c(O)nc1C,,CN(C)C=O,,O,,test
US20140256700A1,CCOC(=O)C1CCc2[nH]c3cc(Br)cc(C(=O)NC)c3c2C1>>CCOC(=O)c1ccc2[nH]c3cc(Br)cc(C(=O)NC)c3c2c1,,C1CCOC1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20120283239A1,CN(C)C(=O)CCl.Cn1nnc2c(C#N)nc(-c3cnc(OCCC4CCNCC4)c(C(F)(F)F)c3)cc21>>CN(C)C(=O)CN1CCC(CCOc2ncc(-c3cc4c(nnn4C)c(C#N)n3)cc2C(F)(F)F)CC1.Cl,,CC#N,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20150148313A1,Cc1cc(Br)ccc1[C@@H](CO)COCc1ccccc1>>Cc1cc(Br)ccc1[C@@H](C=O)COCc1ccccc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20160002177A1,CC(C)N1CCc2c(cccc2-c2cc(OCOCC[Si](C)(C)C)c3ncn(COCC[Si](C)(C)C)c(=O)c3c2)C1.O=C(O)C(F)(F)F>>CC(C)N1CCc2c(cccc2-c2cc(O)c3nc[nH]c(=O)c3c2)C1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20160031904A1,CC1(C)OC(=O)c2c(O)cccc2O1.F[C@H]1CCN(c2ncccc2CCl)C1>>CC1(C)OC(=O)c2c(OCc3cccnc3N3CC[C@H](F)C3)cccc2O1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150210630A1,CCC(C)I.O=C(NCC(=NO)c1ncc(Cl)cc1Cl)c1ccccc1C(F)(F)F>>CCC(C)ON=C(CNC(=O)c1ccccc1C(F)(F)F)c1ncc(Cl)cc1Cl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05403842,Cc1c(-c2ccccc2)oc2c(S(=O)(=O)Cl)cccc2c1=O.NCCO>>Cc1c(-c2ccccc2)oc2c(S(=O)(=O)NCCO)cccc2c1=O,,C1CCOC1,,CCN(CC)CC,O,test
US20020045777A1,CN[C@@H]1CC[C@H](O)CC1.O=C(Cl)OCc1ccccc1>>CN(C(=O)OCc1ccccc1)[C@@H]1CC[C@H](O)CC1,,CCOC(C)=O,,O=C([O-])O.[Na+],,test
US20120101083A1,CC(C)Oc1ncc(-c2nc(-c3ccc4c(c3)CCN(C(=O)[C@@H](NC(=O)OC(C)(C)C)[C@@H](C)O)CC4)no2)cc1C#N.Cl>>CC(C)Oc1ncc(-c2nc(-c3ccc4c(c3)CCN(C(=O)[C@@H](N)[C@@H](C)O)CC4)no2)cc1C#N.Cl,,ClCCl,,C1COCCO1,,test
US04423242,CC(C)C[C@H](N)C(=O)OC(C)(C)C.CCOP(=O)(OCC)C(Cc1ccc(OC)cc1)C(=O)O>>CCOP(=O)(OCC)C(Cc1ccc(OC)cc1)C(=O)N[C@@H](CC(C)C)C(=O)OC(C)(C)C,,C1CCOC1,CN(C)C=O,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20100160373A1,Cc1cc2cnn(CCO[Si](C)(C)C(C)(C)C)c2cc1[N+](=O)[O-]>>Cc1cc2cn[nH]c2cc1N,[Fe],CCO,O,[Cl-].[NH4+],,test
US04016262,CC(=O)N1CN(C(C)=O)C2C(=C1Cl)N(C(C)=O)CN2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O.CN(C)C1CC=CCC1>>CN(CC1CC=CCC1)c1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O,,CCCCO,,CCN(CC)CC,,test
US20090181928A1,CC(=O)O.O=C1CN(c2ccc(/C=C/CCN3C(=O)c4ccccc4C3=O)cc2OCc2ccccc2)S(=O)(=O)N1>>O=C1CN(c2ccc(CCCCNC(=O)c3ccccc3C(=O)O)cc2O)S(=O)(=O)N1,[Pd],,,CCO,,test
US20150166589A1,COc1cc(F)ccc1Oc1cc(Cl)c(Cl)cc1C(=O)Nc1ccn(COP(=O)(OC(C)(C)C)OC(C)(C)C)c(=O)c1>>COc1cc(F)ccc1Oc1cc(Cl)c(Cl)cc1C(=O)Nc1ccn(COP(=O)(O)O)c(=O)c1,,CC#N,O,CC(=O)O,,test
US20110319378A1,COC(=O)C1([C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N([C@H](CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)C3CC3)C2=O)CC1>>COC(=O)C1([C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N([C@H](CO)C3CC3)C2=O)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05739345,Cn1c(COc2ccc(CC3SC(=O)N(C(c4ccccc4)(c4ccccc4)c4ccccc4)C3=O)cc2)nc2ccc(OCc3ccccc3)nc21>>Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccc(O)nc21,[Pd],CO,,,,test
US20160176882A1,BrBr.Cc1cc(O)nc(C2CC2)n1>>Cc1nc(C2CC2)nc(O)c1Br,,O,,[K+].[OH-],,test
US06143877,Cc1cn(C)c2c(OCc3ccccc3)cc3c(c12)C(CO)CN3S(C)(=O)=O>>Cc1cn(C)c2c(OCc3ccccc3)cc3c(c12)[C@H](CO)CN3,,C1CCOC1,CO,CC(=O)O,C[O-].[Na+],test
US05939411,CCNC(=O)OCC1(c2ccccc2)CCN(CCC(CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1.CCNC(=O)OCC1(c2ccccc2)CCN(CCC(CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1.Cl.Cl.O.O.O>>CN(CC(CCN1CCC(CC(=O)O)(c2ccccc2)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1.CN(CC(CCN1CCC(CC(=O)O)(c2ccccc2)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1.Cl.Cl.O.O.O,,CN(C)C=O,,Cl,CC(C)(C)[O-].[K+],test
US04968678,CCOC(=O)C1CC(=CC#N)CCN1C(=O)OC(C)(C)C>>CCOC(=O)[C@H]1C[C@@H](CC#N)CCN1C(=O)OC(C)(C)C,[Pd],CCO,,,,test
US06011044,COc1ccccc1N1CCc2c(Cl)nc3c(OCC(F)(F)F)cccc3c21.NCCCCO>>COc1ccccc1N1CCc2c(NCCCCO)nc3c(OCC(F)(F)F)cccc3c21,,OCCOCCO,,,,test
US20100266509A1,Cc1cc(C)c(S(=O)(=O)ON)c(C)c1.OCc1cccnc1>>Cc1cc(C)c(S(=O)(=O)[O-])c(C)c1.N[n+]1cccc(CO)c1,,ClCCl,,O,,test
US20070197620A1,O=C1CCN1c1ccccc1>>O=C1CCNc2ccccc21,,ClCCCl,,O=S(=O)(O)C(F)(F)F,,test
US20080085890A1,CN.O=C1Cc2ccccc2C(=O)O1>>CNC(=O)Cc1ccccc1C(=O)O,,C1CCOC1,,,,test
US06093732,CCOC(=O)c1cnc2c(F)c(F)c(F)cc2c1O.NCc1ccc(Cl)cc1>>O=C(NCc1ccc(Cl)cc1)c1cnc2c(F)c(F)c(F)cc2c1O,,Cc1ccccc1,,C[Al](C)C,Cl,test
US20100240702A1,CCCC(CC(=O)OCC)n1c(=O)[nH]c2ccccc21.Cc1ccc(C)c(CBr)c1>>CCCC(CC(=O)O)n1c(=O)n(Cc2cc(C)ccc2C)c2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130150339A1,COc1cc(-c2cc(F)cc(F)c2)ccc1-c1nccc2cc(S(=O)(=O)Oc3c(F)c(F)c(F)c(F)c3F)ccc12.Cc1nccc(N)n1>>COc1cc(-c2cc(F)cc(F)c2)ccc1-c1nccc2cc(S(=O)(=O)Nc3ccnc(C)n3)ccc12,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04229449,COc1ccccc1OC(c1ccccc1)C1OCC(=O)N(C)C1=O.Cl>>COc1ccccc1OC(c1ccccc1)C1CN(C)CCO1.Cl,,C1CCOC1,C1CCOC1,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120108566A1,CC(=O)Cl.Cl.NC(=O)c1cnc(Nc2ccc(C3CCNCC3)cc2)cc1NCc1ccccc1F>>CC(=O)N1CCC(c2ccc(Nc3cc(NCc4ccccc4F)c(C(N)=O)cn3)cc2)CC1.Cl,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US20140288123A1,COC(=O)c1ccc([C@H](C)Oc2cccc(Br)c2)cc1>>C[C@H](Oc1cccc(Br)c1)c1ccc(C(=O)O)cc1,,CO,O,[Li+].[OH-],,test
US04200628,C=[N+]=[N-].O=C(O)C(O)C1CN(Cc2ccccc2)CCN1Cc1ccccc1>>COC(=O)C(O)C1CN(Cc2ccccc2)CCN1Cc1ccccc1,,CCOCC,CO,CC(=O)O,,test
US05096890,BrCCc1ccc2c(c1)OCCO2.NC(=O)C(c1ccccc1)(c1ccccc1)C1CCNC1>>NC(=O)C(c1ccccc1)(c1ccccc1)C1CCN(CCc2ccc3c(c2)OCCO3)C1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20040209886A1,Cc1c(O)cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c12.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1c(OS(=O)(=O)C(F)(F)F)cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c12,,CCOC(C)=O,ClCCl,,,test
US04599333,CC(C)(N)COc1ccc(Cl)nn1.Cc1cccc(OCC2CO2)c1Cl>>Cc1cccc(OCC(O)CNC(C)(C)COc2ccc(Cl)nn2)c1Cl,,CO,,,,test
US20080242663A1,CS(=O)(=O)c1cc(N2CCOCC2)cc([N+](=O)[O-])c1>>CS(=O)(=O)c1cc(N)cc(N2CCOCC2)c1,[Pd],CCO,,,,test
US05795903,COc1cc2nc(N)sc2cc1OC(F)(F)F>>Nc1nc2cc(O)c(OC(F)(F)F)cc2s1,,Br,,[Na+].[OH-],,test
US20100087418A1,CC(C)(C)OC(=O)N1CCOc2c(Br)cccc2C1.Cc1noc(C)c1B(O)O>>Cc1noc(C)c1-c1cccc2c1OCCN(C(=O)OC(C)(C)C)C2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20140187545A1,Cc1nn2c(Cl)cc(N3CCOCC3)nc2c1Cc1cccc2ccccc12.c1c[nH]cn1>>Cc1nn2c(-n3ccnc3)cc(N3CCOCC3)nc2c1Cc1cccc2ccccc12,[Cu]I,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20120059028A1,CCCI.COC(=O)Cc1c(C)nc2sc3c(c2c1-c1ccc(Cl)cc1)CCC3>>CCCC(C(=O)OC)c1c(C)nc2sc3c(c2c1-c1ccc(Cl)cc1)CCC3,,CN(C)C=O,,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20070099903A1,CN(C)C(=O)CO.Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCC[C@H]3C(=O)O)CC2)cc2oc(=O)[nH]c12>>Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCC[C@H]3C(=O)OCC(=O)N(C)C)CC2)cc2oc(=O)[nH]c12,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20120114696A1,CCOC(=O)Cc1cc(C(=O)c2ccc3cc(-c4ccc(C(=O)OCc5ccccc5)cc4)n(CCCCN4C(=O)c5ccccc5C4=O)c3c2)sc1Br.OB(O)c1cccc(O)c1>>CCOC(=O)Cc1cc(C(=O)c2ccc3cc(-c4ccc(C(=O)OCc5ccccc5)cc4)n(CCCCN4C(=O)c5ccccc5C4=O)c3c2)sc1-c1cccc(O)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,[Cs+].[F-],test
US20040192688A1,ClCCOc1ccc2ccccc2c1.NCCCc1ccccc1>>c1ccc(CCCNCCOc2ccc3ccccc3c2)cc1,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20030036557A1,CS(=O)(=O)c1ccc(NC(=N)c2ccc(Cl)cc2)cc1.O=C(CBr)c1ccc2ccccc2c1>>CS(=O)(=O)c1ccc(-n2cc(-c3ccc4ccccc4c3)nc2-c2ccc(Cl)cc2)cc1,,CC(C)O,,O=C([O-])O.[Na+],,test
US20050037925A1,Cc1ccc(C)[nH]1.Cc1cccc(C2CC2)c1Oc1nnc(Cl)cc1O.O=C(Cl)Cl>>Cc1cccc(C2CC2)c1Oc1nnc(Cl)cc1OC(=O)n1c(C)ccc1C,,Cc1ccccc1,O,c1ccncc1,,test
US20090030082A1,COC(=O)Cc1cccc(OCCCN(Cc2cc(C(C)(C)C)cc(C(C)(C)C)c2)CC(c2ccccc2)c2ccccc2)c1>>CC(C)(C)c1cc(CN(CCCOc2cccc(CC(=O)O)c2)CC(c2ccccc2)c2ccccc2)cc(C(C)(C)C)c1,,CO,,[Na+].[OH-],,test
US05422358,N#CC(c1ccccc1)(c1ccccc1)[C@H]1CCCNC1.OCc1ccc(CCBr)cc1>>N#CC(c1ccccc1)(c1ccccc1)[C@H]1CCCN(CCc2ccc(CO)cc2)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060035908A1,COC(=O)C(CO[Si](C(C)C)(C(C)C)C(C)C)c1cnc(NC(=O)Nc2cccc(C(F)(F)F)c2)s1>>CC(C)[Si](OCC(CO)c1cnc(NC(=O)Nc2cccc(C(F)(F)F)c2)s1)(C(C)C)C(C)C,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04742061,O=C1CCc2ncc3cc(Cl)c(Cl)cc3c2N1>>Clc1cc2cnc3c(c2cc1Cl)NCCC3,,C1CCOC1,,B,,test
US20070281954A1,CN(C)C1(c2ccccc2)CCC(N)CC1.O=C(Cl)COc1cccc(Cl)c1>>CN(C)C1(c2ccccc2)CCC(NC(=O)COc2cccc(Cl)c2)CC1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,[Na+].[OH-],test
US03947467,Cn1nc(-c2ncc([N+](=O)[O-])n2C)c(C#N)c1N.O=S(=O)(O)O>>Cn1nc(-c2ncc([N+](=O)[O-])n2C)c(C(N)=O)c1N,,CCO,,,,test
US20150203475A1,BrCc1cccc(I)c1.O=C1CCCN1>>O=C1CCCN1Cc1cccc(I)c1,,CN(C)C=O,O,[H-].[Na+],,test
US20060047001A1,Brc1ccc2sccc2c1.COC(Cl)Cl>>O=Cc1csc2ccc(Br)cc12,Cl[Ti](Cl)(Cl)Cl,ClCCCl,,O=C([O-])O.[Na+],,test
US20100256097A1,CCOC(=N)c1ccc(Br)cc1.NNC=O>>Brc1ccc(-c2nc[nH]n2)cc1,,Cc1ccccc1C,,,,test
US20070254925A1,Cc1nc(NC(=O)c2c(F)cccc2F)sc1-c1cc(Br)c2c(c1)OCO2>>Cc1nc(NC(=O)c2c(F)cccc2F)sc1-c1ccc2c(c1)OCO2,[Pd],CCO,,,,test
US20120329830A1,C/C(=C\c1cc2cc(Br)ccc2nc1NC(C)(C)C)C(=O)O.CC1(C)CC([NH3+])CCO1>>C/C(=C\c1cc2cc(Br)ccc2nc1NC(C)(C)C)C(=O)NC1CCOC(C)(C)C1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120289702A1,CC(C)(O)C(O)c1c(F)cccc1Oc1cnc2c(F)cccc2c1>>CC(C)(O)C(=O)c1c(F)cccc1Oc1cnc2c(F)cccc2c1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20050137201A1,NN=C(Nc1cccc(F)c1F)c1c[nH]c2ncccc12.O=N[O-]>>Fc1cccc(-n2nnnc2-c2c[nH]c3ncccc23)c1F,,Cl,O,[Na+].[OH-],,test
US20150057299A1,COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1N.O=C(Cl)CCCCl>>COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1NC(=O)CCCCl,,ClC(Cl)Cl,ClCCl,O,O=C([O-])[O-].[Na+].[Na+],test
US20150266895A1,CNc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(NC(=O)N[C@H](C)c3ccc(F)cc3)ncc12>>CNc1n[nH]c2cc(NC(=O)N[C@H](C)c3ccc(F)cc3)ncc12,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20090163524A1,CC(C)(C)OC(=O)NC1(C(=O)O)CCN(c2ncnc3[nH]ccc23)CC1.CN(C)CCCC(N)c1ccc(Cl)cc1>>CN(C)CCCC(NC(=O)C1(NC(=O)OC(C)(C)C)CCN(c2ncnc3[nH]ccc23)CC1)c1ccc(Cl)cc1,,CC(=O)N(C)C,CCOC(C)=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060293297A1,O=C(O)c1ccc2nc[nH]c2c1.O=S(Cl)Cl>>O=C(Cl)c1ccc2nc[nH]c2c1,,c1ccccc1,,,,test
US20100184815A1,CCCn1nc(Cc2ccc(C)cc2)cc1COC(=O)c1ccc(OC(C)(C)C(=O)OC(C)(C)C)cc1>>CCCn1nc(Cc2ccc(C)cc2)cc1COC(=O)c1ccc(OC(C)(C)C(=O)O)cc1,,CO,,C1COCCO1,Cl,test
US04654343,Cc1nnc2ccc(-c3cccc(N)c3)nn12.O=C(Cl)C1CC1>>Cc1nnc2ccc(-c3cccc(NC(=O)C4CC4)c3)nn12,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110098299A1,C1CCOC1.C=CCBr.CCOC(=O)C1CCCC(=O)C1>>C=CCC1(C(=O)OCC)CCCC2(C1)OCCO2,,CCCCCC,,CC(C)NC(C)C,[Li]CCCC,test
US20080021081A1,C#CCCO[Si](C)(C)C(C)(C)C.CCCC[SnH](CCCC)CCCC>>CCCC[Sn](C=CCCO[Si](C)(C)C(C)(C)C)(CCCC)CCCC,,c1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20090062360A1,COCCOc1ccc(C(NC(=O)OC(C)(C)C)C(=O)OC)cc1>>COCCOc1ccc(C(N)C(=O)OC)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20140213580A1,CC(C)C(=O)Cc1ccccc1.COC(OC)N(C)C>>CC(C)C(=O)C(=CN(C)C)c1ccccc1,,CN(C)C=O,,,,test
US06265418B1,CC(C)(C)OC(=O)Cn1ncc2c1CCN(C(=O)OC(C)(C)C)C2.CCO.O=S(Cl)Cl>>CCOC(=O)Cn1ncc2c1CCNC2.Cl.Cl,,CCO,,,,test
US20120258950A1,Cl.c1ccc(CN2CCc3cccnc3C2)cc1>>Cl.c1cnc2c(c1)CCNC2,[Pd],C1COCCO1,,[H][H],,test
US20130116245A1,CCOC(=O)c1cc(CCCC(=O)O)c[nH]1>>CCOC(=O)c1cc2c([nH]1)C(=O)CCC2,,O=C(O)C(F)(F)F,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US20100221182A1,CC[N+](=O)[O-].COc1cc(C=O)ccc1F>>COc1cc(C(O)C(C)[N+](=O)[O-])ccc1F,,CO,,CC(=O)O,[Na+].[OH-],test
US20100267949A1,COCCOc1cc([N+](=O)[O-])c(C(=O)OC)cc1O.ClOCCCN1CCOCC1>>COC(=O)c1cc(OCCCN2CCOCC2)c(OC)cc1[N+](=O)[O-],,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090143361A1,COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)cc(Cl)c4)n3c2n1.Cc1cscc1B(O)O>>COc1ccc2nc(C)c3c(C)nc(-c4cscc4C)n3c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20040023999A1,CC(C)(C)[Si](C)(C)Cl.OC(CCc1ccccn1)C(F)(F)F>>CC(C)(C)[Si](C)(C)OC(CCc1ccccn1)C(F)(F)F,CN(C)c1ccncc1,ClCCl,,c1c[nH]cn1,,test
US20090099231A1,Cc1ccc(C)n1-c1ccc2c(c1)CCN(C(=O)C(F)(F)F)C2>>Cc1ccc(C)n1-c1ccc2c(c1)CCNC2,,CO,ClCCl,O,O=C([O-])[O-].[K+].[K+],test
US20150018422A1,Br[Mg]C1CC1.COCOCc1cc(C#N)ccn1.[OH-]>>COCOCc1cc(C(=O)C2CC2)ccn1,,C1CCOC1,,Cl,,test
US04038396,N#CCc1ccc(C(=O)Cl)cc1.Nc1cccnc1O>>N#CCc1ccc(-c2nc3cccnc3o2)cc1,,c1ccncc1,,,,test
US20070149508A1,CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc(Nc3ncc(C=Cc4cccc(N)c4)cn3)cc2)CC1>>Nc1cccc(C=Cc2cnc(Nc3ccc(S(=O)(=O)C4CCNCC4)cc3)nc2)c1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US05532380,CC(=O)OC(C)=O.OCC1OCOC1CO>>CC(=O)OCC1OCOC1COC(C)=O,,c1ccncc1,,CCO,,test
US04816463,COC(=O)C1CC2=C(CN1C(=O)C(c1ccccc1)c1ccccc1)N(CC(=O)c1ccccc1)CN2.FC(F)(F)c1cccc(CCl)c1>>COC(=O)C1Cc2c(ncn2Cc2cccc(C(F)(F)F)c2)CN1C(=O)C(c1ccccc1)c1ccccc1,,CCOCC,,CC#N,,test
US20140350019A1,CCOC(=O)COc1ccc(F)c(NCc2cc(O)cc(-c3cccc(F)c3)c2F)c1F>>O=C(O)COc1ccc(F)c(NCc2cc(O)cc(-c3cccc(F)c3)c2F)c1F,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20060167066A1,COC(=O)/C=C/c1cc(O)c2c(c1)C(C(=O)OC)C(c1ccc(O)c(O)c1)O2>>c1ccc2occc2c1,,ClCCl,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US05750574,CCOc1c(OCC)c(=O)c1=O.C[C@@H](N)C(C)(C)C>>CCOc1c(N[C@H](C)C(C)(C)C)c(=O)c1=O,,CCO,,,,test
US20050020619A1,Cc1cccc(NC(=O)Nc2ccc(-c3c(C)sc4c([N+](=O)[O-])cnc(N)c34)cc2)c1>>Cc1cccc(NC(=O)Nc2ccc(-c3c(C)sc4c(N)cnc(N)c34)cc2)c1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20080214754A1,C=CCC(CC=C)(C(=O)OCC)C(=O)OCC.CNC(N)=O>>C=CCC1(CC=C)C(=O)NC(=O)N(C)C1=O,,CCO,,[Na],,test
US20090163469A1,CC(=O)Nc1nc(C)cs1.O=C1CCC(=O)N1I>>CC(=O)Nc1nc(C)c(I)s1,,CC#N,,,,test
US20160194307A1,Cc1c(CO)cccc1-c1ccccc1.O=Cc1ccc(O)c(Br)c1>>Cc1c(COc2ccc(C=O)cc2Br)cccc1-c1ccccc1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150018343A1,COC(=O)C(C)Oc1ccccc1C=O>>CC(CO)Oc1ccccc1CO,,C1COCCO1,,[BH4-].[Li+],,test
US20150210727A1,CC(=O)c1cccc(C(C)(C)N)c1.O=C(Cl)Cc1ccc(Cl)cc1>>CC(=O)c1cccc(C(C)(C)NC(=O)Cc2ccc(Cl)cc2)c1,,ClCCl,,CCN(CC)CC,,test
US20100075994A1,CC1(C)C=C(c2ccc(OCc3ccccc3)cc2)CCC1>>CC1(C)CCCC(c2ccc(O)cc2)C1,[Pd],CCOC(C)=O,CO,,,test
US05248810,CC(C)(C)[SiH2]OCCCCC(=C(F)F)C(F)(F)F>>OCCCCC(=C(F)F)C(F)(F)F,,CO,,,,test
US20090105259A1,CC(C)(C)OC(=O)NC[C@H]1OC(C)(C)O[C@@H]1CN1C(=O)c2ccccc2C1=O>>CC(C)(C)OC(=O)NC[C@H]1OC(C)(C)O[C@@H]1CN,,CCO,,NN,,test
US20120010187A1,Nc1ncc([N+](=O)[O-])s1.O=C1CCCC(=O)O1>>O=C(O)CCCC(=O)Nc1ncc([N+](=O)[O-])s1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,,,test
US20020007068A1,COC(=O)C(C)(C)c1ccc(C(O)CCCN2CCC(C(O)(c3ccc(C)cc3)c3ccc(C)cc3)CC2)cc1>>CC(C)(C(=O)O)c1ccccc1,,O,,CO,[Na+].[OH-],test
US20100022544A1,ClCc1csc(-c2ccc(Cl)cc2)n1.N#Cc1c(N)nc(S)c(C#N)c1C1CCCOC1>>N#Cc1c(N)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1C1CCCOC1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20140088075A1,COc1ccc(CNc2cc3c(cn2)cc(-c2cc(N)c(F)cc2Cl)c(=O)n3C(C)C)cc1.O=C=Nc1cccc(F)c1>>COc1ccc(CNc2cc3c(cn2)cc(-c2cc(NC(=O)Nc4cccc(F)c4)c(F)cc2Cl)c(=O)n3C(C)C)cc1,,C1CCOC1,,,,test
US20080207708A1,CC(C)COc1ccc(Cl)cc1C(F)(F)c1nc(C(=O)O)cs1.Nc1ccccc1N.O=P(Cl)(Cl)Cl>>CC(C)COc1ccc(Cl)cc1C(F)(F)c1nc(-c2nc3ccccc3[nH]2)cs1.Cl,,O=P(Cl)(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US20120322784A1,CC(C)OC(=O)N1CCC(C2Cc3ccccc3O2)CC1.O=C1CCC(=O)N1Br>>CC(C)OC(=O)N1CCC(C2Cc3cc(Br)ccc3O2)CC1,,CN(C)C=O,,CCOC(C)=O,O,test
US04479942,CC(C)(C)OC(=O)NC(Cc1ccc(F)cc1)C(=O)N[C@H]1[C@@H](O)[C@H](n2cnc3c(N)ncnc32)O[C@@H]1C(=O)O>>Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(=O)O)[C@@H](NC(=O)C(N)Cc2ccc(F)cc2)[C@H]1O,,O=CO,,,,test
US20100113438A1,CC(=O)c1ccc(N2CCN(C)CC2)cc1.CC(C)(C)OC(=O)/C=C/c1ccc(C=O)cn1>>CN1CCN(c2ccc(C(=O)/C=C/c3ccc(/C=C/C(=O)OC(C)(C)C)nc3)cc2)CC1,,CCO,,[K+].[OH-],,test
US20090093483A1,CC(C)(C)OC(=O)CN.CCOC(=O)C1=C(O)c2ccc(Cl)cc2C(C)(C)C1=O>>CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2ccc(Cl)cc2C(C)(C)C1=O,,C1COCCO1,CCOCC,CCN(C(C)C)C(C)C,Cl,test
US20020028832A1,CCCCCCCCNC(=O)N1CCC(Nc2ccc(CCNCC(O)c3ccc(OCc4ccccc4)c(C(N)=O)c3)cc2)CC1>>CCCCCCCCNC(=O)N1CCC(Nc2ccc(CCNCC(O)c3ccc(O)c(C(N)=O)c3)cc2)CC1,[Pd],CCO,,[H][H],,test
US20100286161A1,CC(C)(C)OC(=O)N(c1ccc(Cl)cc1)c1cncc(Cl)n1.OB(O)c1cc[nH]n1>>CC(C)(C)OC(=O)N(c1ccc(Cl)cc1)c1cncc(-c2ccn[nH]2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,O,O=C([O-])[O-].[Na+].[Na+],,test
US05837719,O=C(OCc1ccccc1)c1c(-c2ccccc2)[nH]c(-c2ccc(F)cc2)c1-c1ccncc1>>O=C(O)c1c(-c2ccccc2)[nH]c(-c2ccc(F)cc2)c1-c1ccncc1,[Pd],CCO,,,,test
US20100303928A1,CCOC(=O)c1nc(-c2ccccc2)c2onc(-c3ccccc3)c2c1O.NCC(=O)O>>O=C(O)CNC(=O)c1nc(-c2ccccc2)c2onc(-c3ccccc3)c2c1O,,CO,,C[O-].[Na+],,test
US06165944,CC(C)c1noc(-c2c(Cl)ccc(C(=O)Cl)c2Cl)n1.Cn1nccc1O>>CC(C)c1noc(-c2c(Cl)ccc(C(=O)c3cnn(C)c3O)c2Cl)n1,,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US06362203B1,COC(=O)C(CCBr)(c1ccccc1)c1ccccc1.Oc1ccccc1C1(O)CCNCC1>>COC(=O)C(CCN1CCC(O)(c2ccccc2O)CC1)(c1ccccc1)c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20150025053A1,CO/N=C(\C(=O)O)c1csc(N)n1.O=C1CCC(=O)N1Cl>>CO/N=C(\C(=O)O)c1nc(N)sc1Cl,,CN(C)C=O,,,,test
US20040072871A1,CCOC(=O)c1ccc(C#N)cc1C(=O)OCC>>CCOC(=O)c1ccc(CN)cc1C(=O)OCC,[Pd],CCO,,Cl,[H][H],test
US20080176898A1,C=CCOC(=O)Cc1cc(C(=O)OCC)ccc1OCCCc1ccc(OCCCCOC2CCCCC2)cc1>>CCOC(=O)c1ccc(OCCCc2ccc(OCCCCOC3CCCCC3)cc2)c(CC(=O)O)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,C1COCCN1,,test
US20070099924A1,CCOC(=O)CC(C)Br.Nc1cccc(Br)c1>>CCOC(=O)CCCNc1cccc(Br)c1,,Cc1ccccc1,,CCN(CC)CC,,test
US04002623,CN1CCN(CCCNc2ccccc2N)CC1.O=C(N=C=S)c1ccccc1>>CN1CCN(CCCn2c(NC(=O)c3ccccc3)nc3ccccc32)CC1,,CCO,,,,test
US05371080,CC(C)CC(N)=NO.CCOC(=O)c1ncn2c1nc(N1CCOCC1)c1cc(F)ccc12>>CC(C)c1noc(-c2ncn3c2nc(N2CCOCC2)c2cc(F)ccc23)n1,,CN(C)C=O,ClCCl,CC(=O)O,[H-].[Na+],test
US20160214972A1,CCOC(=O)COCCOCCNC(=O)OC(C)(C)C.Cl>>CCOC(=O)COCCOCCN.Cl,,C1COCCO1,,,,test
US04808624,CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCCCN1C(=O)c2ccccc2C1=O>>CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCCCN,,CCO,,NN,O,test
US04851419,CN(C)c1ccccc1S(=O)c1nc2cc([N+](=O)[O-])ccc2[nH]1>>CN(C)c1ccccc1S(=O)c1nc2cc(N)ccc2[nH]1,O=[Pt]=O,CCO,,,,test
US20110092479A1,O=[N+]([O-])c1cnc2[nH]nc(CO)c2c1>>Nc1cnc2[nH]nc(CO)c2c1,[Fe],O,,CCO,[Cl-].[NH4+],test
US20040005986A1,C#CCN1C(=O)COc2cc(F)c(NN)cc21.O=C(C(Br)Br)C(F)(F)F>>C#CCN1C(=O)COc2cc(F)c(NN=CC(=O)C(F)(F)F)cc21,,O,,CC(=O)[O-].[Na+],,test
US20080234250A1,COC(=O)CCNc1c(F)cccc1[N+](=O)[O-]>>O=C1CCNc2c(F)cccc2N1,[Pd],CO,,,,test
US20160272628A1,CC1c2cc(-c3cn(C(=O)OC(C)(C)C)c4cc(F)ccc34)ccc2S(=O)(=O)N1C1CNC(=O)C1>>CC1c2cc(-c3c[nH]c4cc(F)ccc34)ccc2S(=O)(=O)N1C1CNC(=O)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04288434,N#CCON=C(C(=O)OCC#N)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>N#CCON=C(C(=O)O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20100029621A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(NC(=O)NCC3CC3)cc2)CC1>>O=C(NCC1CC1)Nc1ccc(C(=O)N2CCNCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06417192B1,C#CCCCCCCO.Clc1ccc(I)cc1Cl>>OCCCCCCC#Cc1ccc(Cl)c(Cl)c1,[Cu]I,CCN(CC)CC,,,,test
US04085210,C#CCBr.C(=C1c2ccccc2CCc2ccccc21)C1CNCCO1>>C#CCN1CCOC(C=C2c3ccccc3CCc3ccccc32)C1,,CCO,O,[K+].[OH-],,test
US04476316,C1=CC2CCC1C2.CCOC(N)=O>>CCOC(=O)NC12CCC(CC1)C2,,CCO,,,,test
US20030100576A1,Cc1onc2c1c(=O)n(C1CCCC(NC(=O)C(Cc3ccccc3)NC(=O)OC(C)(C)C)C1)c1cccc(Cl)c21>>Cc1onc2c1c(=O)n(C1CCCC(NC(=O)C(N)Cc3ccccc3)C1)c1cccc(Cl)c21,,Cl,,,,test
US20120184542A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=C1c2ccccc2C(=O)N1[C@H](CCO)c1ccccc1>>Cc1ccc(S(=O)(=O)OCC[C@H](c2ccccc2)N2C(=O)c3ccccc3C2=O)cc1,,ClCCl,,c1ccncc1,,test
US20140142102A1,CS(=O)(=O)N1CCNCC1.O=Cc1cccc(Br)n1>>CS(=O)(=O)N1CCN(c2cccc(C=O)n2)CC1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20070149608A1,Cc1cc(O)cc(C)c1Br.Cc1cccc(Br)n1>>Cc1cccc(Oc2cc(C)c(Br)c(C)c2)n1,[Cu],CCOC(C)=O,,[Na],,test
US06008213,CCOC(=O)CC1=Cc2ccc(CCCCOC3CCCCO3)cc2Cc2ccccc21>>CCOC(=O)CC1=Cc2ccc(CCCCO)cc2Cc2ccccc21,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100249123A1,CC(C)(C#N)c1ccc(N)cc1Br.OB(O)c1ccc(Cl)cc1>>CC(C)(C#N)c1ccc(N)cc1-c1ccc(Cl)cc1,,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20110059954A1,COc1ccc2c(c1)CCN(C1CCNCC1)C(=O)N2.Cc1cc(C(=O)c2cc(Cl)ncn2)cc(C)c1OCc1ccccc1>>COc1ccc2c(c1)CCN(C1CCN(c3cc(C(=O)c4cc(C)c(OCc5ccccc5)c(C)c4)ncn3)CC1)C(=O)N2,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20150239866A1,C#Cc1cc(C)cc(Nc2nccc(C(F)F)n2)c1.CC(N=[N+]=[N-])C1CNC(=O)O1>>Cc1cc(Nc2nccc(C(F)F)n2)cc(-c2cn(C(C)C3CNC(=O)O3)nn2)c1,,CC(C)(C)O,O,O=C(CO)O[CH][C@@H](O)CO,C[O-].[Na+],test
US20110312908A1,COC(=O)c1cc2c(Nc3ccc(OC(F)(F)F)cc3)ncnc2s1>>O=C(O)c1cc2c(Nc3ccc(OC(F)(F)F)cc3)ncnc2s1,,C1CCOC1,O,[Li+].[OH-],,test
US04827004,C=C(C)C(=O)CC/C(C)=C/CC/C(C)=C/C(N)=O.OCCS>>C/C(=C\C(N)=O)CC/C=C(\C)CCC(=O)C(C)CCCO,,CO,,CCN(CC)CC,,test
US20090062253A1,CC(C)(C)c1ccc(C(=O)c2ccc[nH]2)cc1.COC(=O)CCCBr>>COC(=O)CCCn1cccc1C(=O)c1ccc(C(C)(C)C)cc1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04746352,CCOC(=O)C1=C(NC(=O)Nc2ccc(Cl)c(C(=O)OCC)c2)CCC1>>CCOC(=O)c1cc(-n2c(=O)[nH]c3c(c2=O)CCC3)ccc1Cl,,COCCOC,,CC(=O)O,[H-].[Na+],test
US20130317023A1,Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F.O=S(=O)(Cl)c1ccoc1>>O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F)c1ccoc1,,ClCCl,,c1ccncc1,,test
US03978132,Cc1ccc(C(=O)C(C)(C)C)cc1.NC(=O)CCC(=O)NBr>>CC(C)(C)C(=O)c1ccc(CBr)cc1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20140228386A1,O=C1N(c2ccnc(Cl)c2)CCN1c1cnccc1C1CC1.OB(O)C1CC1>>O=C1N(c2ccnc(C3CC3)c2)CCN1c1cnccc1C1CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1C,,O=C([O-])[O-].[K+].[K+],,test
US20130053396A1,N#Cc1ccc2ccccc2n1.NO>>N=C(NO)c1ccc2ccccc2n1,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20160229814A1,CCn1c(=O)n(CC(=O)N(C)C)c(=O)c2cc([N+](=O)[O-])ccc21>>CCn1c(=O)n(CC(=O)N(C)C)c(=O)c2cc(N)ccc21,[Pd],CCOC(C)=O,,[H][H],,test
US20090048239A1,COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)C[C@@H](N(CCNC(=O)OC(C)(C)C)Cc1ccccc1)COc1cc(F)ccc1-3>>CC(C)(C)OC(=O)NCCN(Cc1ccccc1)[C@H]1COc2cc(F)ccc2-c2c(C3CCCCC3)c3ccc(C(=O)O)cc3n2C1,,C1COCCO1,,Cl,[K+].[OH-],test
US04812164,C#CCBr.CCOc1nc(C(F)(F)C(F)(F)F)cc(=O)n1-c1cc(O)c(Cl)cc1F>>C#CCOc1cc(-n2c(OCC)nc(C(F)(F)C(F)(F)F)cc2=O)c(F)cc1Cl,,CC(C)=O,,O=C([O-])[O-].[Na+].[Na+],,test
US06110924,BrBr.COc1ccc(C2C(=O)NC(=O)NC2=O)cc1>>COc1ccc(C2(Br)C(=O)NC(=O)NC2=O)cc1,,O,,Br,,test
US20020010177A1,N#CC(c1ccccn1)c1c(Cl)cc(N)cc1Cl.O=S(=O)(O)O>>NC(=O)C(c1ccccn1)c1c(Cl)cc(N)cc1Cl,,O=S(=O)(O)O,,[NH4+].[OH-],,test
US20100016319A1,C1COCCN1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(C(F)(F)F)ccc2Oc2ccnc(Cl)n2)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(C(F)(F)F)ccc2Oc2ccnc(N3CCOCC3)n2)cc1,,CCO,,,,test
US20030064993A1,CCCCN(CC)c1nc(C)nc2c1NC(=N)CN2c1ccc(C(C)C)cc1Br.CCOC(CBr)OCC>>CCCCN(CC)c1nc(C)nc2c1-n1ccnc1CN2c1ccc(C(C)C)cc1Br,,CCO,,,,test
US20100298288A1,CC(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)N4CCC5(CCNCC5)C4)cc3)oc12.FC(F)(F)c1ccc(CBr)cc1>>CC(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)N4CCC5(CCN(Cc6ccc(C(F)(F)F)cc6)CC5)C4)cc3)oc12,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100075968A1,CN1C(=O)N(c2ccc(F)nc2)CC1C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CN1C(=O)N(c2ccc(F)nc2)CC1C(=O)O.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20130281490A1,C[C@@H](O)[C@@H](N)C(=O)O.O=C([O-])n1cccc(CCCCCc2ccccc2)c1=O>>C[C@@H](O)[C@@H](NC(=O)OCCCCCc1ccccc1)C(=O)O,,C1CCOC1,O,O=C([O-])O.[Na+],,test
US20100168175A1,CCCCN(C)C(=O)c1c(O)c(OC)c(OC)n(Cc2ccc(OC)cc2)c1=O>>CCCCN(C)C(=O)c1c(O)c(OC)c(OC)[nH]c1=O,[Pd],C1CCOC1,CO,,,test
US20070225332A1,CC(=O)OCBr.CC(C)Oc1ccc(Oc2ncc(-c3noc(C(C)N)n3)s2)cc1>>COC(=O)CNC(C)c1nc(-c2cnc(Oc3ccc(OC(C)C)cc3)s2)no1,,CC#N,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US20090270374A1,CO[C@H]1CNC[C@@H](CN2C(=O)c3ccccc3C2=O)C1.COc1ccc2ncc(=O)n(CC=O)c2n1>>COc1ccc2ncc(=O)n(CCN3CC(CN4C(=O)c5ccccc5C4=O)CC(OC)C3)c2n1,,CO,ClC(Cl)Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100130492A1,CC(=O)Cl.CC(C)Cn1c(N2CCNCC2)nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc21>>CC(=O)N1CCN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC(C)C)CC1,,CN1CCCC1=O,,CCN(CC)CC,,test
US20080269266A1,CC(=NO)c1ncccn1.CON(C)C(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCC[C@H]1[C@]1(O)CC(c2ncccn2)=NO1,,C1CCOC1,O,CC(C)NC(C)C,[Li]CCCC,test
US20130252937A1,Cc1cc(O)cc(C)c1Br.N#CCBr>>Cc1cc(OCC#N)cc(C)c1Br,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060094843A1,CC(C)CCBr.CCOC(=O)C1CCCC1=O>>CCOC(=O)C1(CCC(C)C)CCCC1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040077584A1,COC(=O)c1nc(NCC(c2ccccc2)c2ccccc2)c2ncn([C@@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]3OC(C)=O)c2n1>>COC(=O)c1nc(NCC(c2ccccc2)c2ccccc2)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1,,CO,,O=C([O-])[O-].[Na+].[Na+],,test
US06448266B1,CC(C)CCOC(=O)C1(NC(=O)OC(C)(C)C)CC(OCc2ccccc2)C1>>CC(C)(C)OC(=O)NC1(C(=O)O)CC(OCc2ccccc2)C1,,CO,,O,[Na+].[OH-],test
US20040048908A1,O=S(Cl)Cl.OCc1cnoc1-c1ccc(C(F)(F)F)cc1>>FC(F)(F)c1ccc(-c2oncc2CCl)cc1,,Cc1ccccc1,,C1CCOC1,,test
US04205085,CCOC(=O)CNC(=O)c1ccc(NCCCCCCCCCCCCCCCC(F)(F)F)cc1>>O=C(O)CNC(=O)c1ccc(NCCCCCCCCCCCCCCCC(F)(F)F)cc1,,CCO,,[Na+].[OH-],,test
US20130053565A1,CC(C)(C)OC(=O)N1CC(=O)[C@@H]1Cc1ccccc1.CCCC#CCCC>>CCCC1=C(CCC)C(=O)C(Cc2ccccc2)N(C(=O)OC(C)(C)C)C1,,Cc1ccccc1,,,,test
US20110263559A1,O=c1[nH]n(-c2ccccc2)c2cc(Br)ccc12.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>Sc1nn(-c2ccccc2)c2cc(Br)ccc12,,Cc1ccccc1C,,,,test
US06265434B1,COC(=O)c1ccc(CCCC2CCN(C[C@H]3CN([C@@H](C(=O)O)C4CCCCC4)C[C@@H]3c3ccccc3)CC2)cc1>>O=C(O)c1ccc(CCCC2CCN(C[C@H]3CN([C@@H](C(=O)O)C4CCCCC4)C[C@@H]3c3ccccc3)CC2)cc1,,CO,,[Na+].[OH-],,test
US06232467B1,C1COCCN1.CCCC/C=C/B(O)O.O=CC(=O)O>>CCCC/C=C/C(C(=O)O)N1CCOCC1,,CCO,,O,,test
US20140256734A1,CC(C)(C)OC(=O)N1CC[C@H](Oc2nc(C#N)cc3cccc(Cl)c23)C1.NN>>CC(C)(C)OC(=O)N1CC[C@H](Oc2nc(C(=N)NN)cc3cccc(Cl)c23)C1,,CO,,O,,test
US04920140,CCCCCCCCCC(C)(C)c1cc(Br)ccc1O.CI>>CCCCCCCCCC(C)(C)c1cc(Br)ccc1OC,,C1CCOC1,,[H-].[Na+],,test
US20090156643A1,FC(F)(F)C1(c2cc(Cl)cc(Cl)c2)CC(c2ccc(CCl)cc2)=NO1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1Cc1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1,,CCOC(C)=O,CN(C)C=O,[K],,test
US20040067968A1,O=C(c1ccc(Cl)cc1)c1ccc2[nH]c(=O)cc(-n3ccnc3)c2c1>>O=c1cc(-n2ccnc2)c2cc(C(O)c3ccc(Cl)cc3)ccc2[nH]1,,C1CCOC1,CO,O,[BH4-].[Na+],test
US20080280948A1,COCCN.COc1cc(Nc2ncc(C=O)s2)ccc1-n1cnc(C)c1>>COCCNCc1cnc(Nc2ccc(-n3cnc(C)c3)c(OC)c2)s1,,ClCCl,,C1CCOC1,,test
US20050282827A1,CCOc1cc(C#N)c([N+](=O)[O-])cc1C(F)(F)F>>CCOc1cc(C#N)c(N)cc1C(F)(F)F,[Fe],CO,Cl,,,test
US20100240658A1,CCCS(=O)(=O)Cl.COC(=O)c1ccc(-c2noc(-c3ccc(N4CCCCC4C)c(N)c3)n2)cc1F>>CCCS(=O)(=O)Nc1cc(-c2nc(-c3ccc(C(=O)OC)c(F)c3)no2)ccc1N1CCCCC1C,,CCOC(C)=O,,,,test
US20110118245A1,COCCOc1ccc([N+](=O)[O-])c(C(=O)OC)c1>>COCCOc1ccc(N)c(C(=O)OC)c1,[Pd],CO,,,,test
US20060194843A1,Nc1c[nH]nc1C(=O)Nc1ccc(F)cc1.O=C1CCCCC1>>O=C(Nc1ccc(F)cc1)c1n[nH]cc1NC1CCCCC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20040082651A1,CC(=O)OC(C/C=C(\C)CCC=C(C)C)(C(C)=O)C(=O)OC(C)(C)C>>CC(=O)OC(C/C=C(\C)CCC=C(C)C)C(C)=O,,CS(C)=O,O,[Cl-].[Li+],,test
US20130336920A1,CNCC1(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)C=CC=CN1.O=C(O)CN1CCOCC1>>CN(CC1(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)C=CC=CN1)C(=O)CN1CCOCC1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20040167171A1,COC(=O)/C=C/c1ccc(F)cc1.COC(=O)CC(=O)OC>>COC(=O)CC(c1ccc(F)cc1)C(C(=O)OC)C(=O)OC,,C1CCOC1,CO,C[O-].[Na+],,test
US20140155389A1,CC(C)(C)OC(=O)N1CCN(c2cc(F)c(N(Cc3ccccc3)Cc3ccccc3)cc2F)CC1>>CC(C)(C)OC(=O)N1CCN(c2cc(F)c(N)cc2F)CC1,[Pd],CO,,,,test
US20070219187A1,COc1ccc(-c2noc(C3CCCNC3)n2)cc1.O=C(Cl)c1ccc(F)cc1>>COc1ccc(-c2noc(C3CCCN(C(=O)c4ccccc4)C3)n2)cc1,,C1CCOC1,,Cl,c1ccncc1,test
US20150353573A1,O=C(O)C(F)(F)C1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>OCC(F)(F)[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,,C1CCOC1,,,,test
US20110039892A1,N#CC(C(N)=O)C1OC(=O)C(Cl)=C1Cl.NC1(c2ccccc2)CC1>>N=c1c(C(N)=O)cc(Cl)cn1C1(c2ccccc2)CC1,,CO,,CCN(CC)CC,Cl,test
US08754114B2,Cn1ccc(S(=O)(=O)Cl)n1.N#CCC1(n2cc(-c3cnn4c(-c5cccc(NC(=O)NCC(F)(F)F)c5)cnc4c3)cn2)CNC1>>Cn1ccc(S(=O)(=O)N2CC(CC#N)(n3cc(-c4cnn5c(-c6cccc(NC(=O)NCC(F)(F)F)c6)cnc5c4)cn3)C2)n1,,CC#N,CO,CCN(CC)CC,,test
US05006519,CC(C)(C)[Si](C)(C)Cl.OCc1cc(Br)cc2ccccc12>>CC(C)(C)[Si](C)(C)OCc1cc(Br)cc2ccccc12,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20110152533A1,CCCCCCOC(=O)Cl.Cc1cc(C(=O)NCc2ccc(C(=N)N)cc2)c(C)n1-c1ccc(F)cc1>>CCCCCCOC(=O)/N=C(\N)c1ccc(CNC(=O)c2cc(C)n(-c3ccc(F)cc3)c2C)cc1,,C1CCOC1,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20140248218A1,CC1(C)OB(c2ccc(CBr)cc2)OC1(C)C.O=c1ccc2ccc(O)cc2o1>>CC1(C)OB(c2ccc(COc3ccc4ccc(=O)oc4c3)cc2)OC1(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130237525A1,COC(=O)CCCC(NS(=O)C(C)(C)C)c1c(OC)cccc1OC>>COC(=O)CCCC(N)c1c(OC)cccc1OC,,CO,,C1COCCO1,Cl,test
US07005440B1,CCOC(=O)CBr.c1cc(Cc2c[nH]c3ccccc23)cc(OCc2ccc3ccccc3n2)c1>>O=C(O)Cn1cc(Cc2cccc(OCc3ccc4ccccc4n3)c2)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20160024050A1,Brc1ccc(CNC2CN(C3CCCC3)C2)cc1.O=C(O)C=Cc1ccc(C(F)(F)F)cc1>>O=C(/C=C/c1ccc(C(F)(F)F)cc1)N(Cc1ccc(Br)cc1)C1CN(C2CCCC2)C1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20160264598A1,COc1c(CC(NC(=O)CCC(F)(F)F)B2OC3CC4CC(C4(C)C)C3(C)O2)cccc1C(=O)OC(C)(C)C>>O=C(CCC(F)(F)F)N[C@H]1Cc2cccc(C(=O)O)c2OB1O,,ClCCl,,ClB(Cl)Cl,,test
US05162391,C=C(C)C(=O)Cl.C[Si](C)(C)O[Si](CCCN)(O[Si](C)(C)C)O[Si](C)(C)C>>C=C(C)C(=O)NCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C,,CCOCC,,O,c1ccncc1,test
US20030199491A1,N#CCc1c([N+](=O)[O-])ccc(OCc2ccccc2)c1F.N#CCc1cc(OCc2ccccc2)c(F)cc1[N+](=O)[O-]>>Oc1cc2cc[nH]c2cc1F.Oc1ccc2[nH]ccc2c1F,[Pd],CC(=O)O,CCO,[H][H],,test
US06358980B1,CC#CCOc1ccc(S(=O)(=O)C2(C(=O)OC)CCNCC2)cc1.O=S(=O)(Cl)C(F)(F)F>>CC#CCOc1ccc(S(=O)(=O)C2(C(=O)OC)CCN(S(=O)(=O)C(F)(F)F)CC2)cc1,,ClC(Cl)Cl,,CCN(CC)CC,CN(C)c1ccccn1,test
US20120309842A1,C[C@@H](N)c1cccc2ccccc12.ClC=CCCl>>C[C@@H](NCC=CCl)c1cccc2ccccc12.Cl,,CC#N,O,[I-].[K+],,test
US06130239,C#CCCO.COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(Br)c21>>COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(C#CCCO)c21,,CCN(CC)CC,CN(C)C=O,C[Si](C)(C)Cl,,test
US20130289033A1,O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccccc1I.OB(O)c1ccc(F)cc1>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccccc1-c1ccc(F)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20080167361A1,COc1ccc(S(=O)(=O)c2ccc(C3CCN(C(=O)OC(C)(C)C)C3)c(C)c2)cc1>>COc1ccc(S(=O)(=O)c2ccc(C3CCNC3)c(C)c2)cc1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20150225367A1,C=CS(=O)(=O)NC1CCN(c2ccc(-c3c[nH]c4cc(F)ccc34)cn2)CC1.CNC>>CN(C)CCS(=O)(=O)NC1CCN(c2ccc(-c3c[nH]c4cc(F)ccc34)cn2)CC1,,C1CCOC1,,,,test
US03966953,CC1SC(=NO)N(N(C)C)C1=O.CN=C=O>>CNC(=O)ON=C1SC(C)C(=O)N1N(C)C,CCN(CC)CC,CC(C)=O,,,,test
US20150057260A1,COC(=O)c1cc(Cl)nc(Cl)n1.c1cn[nH]c1>>COC(=O)c1cc(-n2cccn2)nc(Cl)n1,,CCCCO,,O=C([O-])O.[Na+],,test
US20120252801A1,CC(C)(C)OC(=O)C(C)(C)Br.CCN1CC(=O)OC(C)(C)C1>>CCN1CC(C)(C)OC(=O)C1C(C)(C)C(=O)OC(C)(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20120108582A1,C=C1C[C@@H]2C(=O)N([C@H](C)c3ccccc3)C[C@]2(C(=O)OC(C)(C)C)C1>>C=C1C[C@@H]2C(=O)N([C@H](C)c3ccccc3)C[C@]2(C(=O)O)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04954503,NNC(=O)c1ccccc1Br.O=S(=O)(Cl)c1ccccc1>>O=C(NNS(=O)(=O)c1ccccc1)c1ccccc1Br,,c1ccncc1,,,,test
US20130225620A1,CNCc1ccc2[nH]cnc2c1C.Clc1nccc(Nc2cc(C3CC3)n[nH]2)n1>>Cc1c(CN(C)c2nccc(Nc3cc(C4CC4)[nH]n3)n2)ccc2[nH]cnc12,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US05652361,COc1ccc([N+](=O)[O-])cc1CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1>>COc1ccc(N)cc1CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1,O=[Pt]=O,,,,,test
US20050154042A1,CCCCN.O=Cc1ccccc1>>CCCCN=Cc1ccccc1,,c1ccccc1,,,,test
US20150166512A1,CCc1ccc(Cl)cc1-n1cccc1C#N.O=C1CCC(=O)N1Br>>CCc1ccc(Cl)cc1-n1cc(Br)cc1C#N,,C1CCOC1,,,,test
US20110124597A1,BrCCCBr.O=Cc1cccc(O)c1Br>>O=Cc1cccc(OCCCBr)c1Br,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20120122863A1,COC(=O)CC1(CN)CCCCC1.O=C(Cl)c1ccccc1[N+](=O)[O-]>>COC(=O)CC1(CNC(=O)c2ccccc2[N+](=O)[O-])CCCCC1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20040209921A1,COc1ccc(CN(Cc2ncccc2C)C(C)c2ccccn2)c(C#N)c1>>COc1ccc(CN(Cc2ncccc2C)C(C)c2ccccn2)c(CN)c1,[Ni],CO,,N,,test
US20100130738A1,CCc1ccc2c(C(=O)C(C)C(=O)OC)ccc(OC)c2n1.CI>>CCc1ccc2c(C(=O)C(C)(C)C(=O)OC)ccc(OC)c2n1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20140349993A1,COC(=O)c1cccc(N2CCC2)n1>>O=C(O)c1cccc(N2CCC2)n1,,CO,,Cl,[K+].[OH-],test
US20120149723A1,C[C@H]1CC[C@@H](CCOc2ccc(F)cn2)N(C(=O)OC(C)(C)C)C1>>C[C@H]1CC[C@@H](CCOc2ccc(F)cn2)NC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110230497A1,CCOC(=O)[C@H]1CC2(CCN1[C@@H](C)c1ccccc1)OCCO2>>C[C@@H](c1ccccc1)N1CCC2(C[C@@H]1CO)OCCO2,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06686353B1,CC(C)(C)OC(=O)N1CCCNCC1.O=C(CCCl)c1ccccc1>>CC(C)(C)OC(=O)N1CCCN(CCC(=O)c2ccccc2)CC1,,CC#N,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20160052884A1,COc1cc(I)c(O)cn1.O=S(=O)(OC(F)F)C(F)(F)F>>COc1cc(I)c(OC(F)F)cn1,,CC#N,O,[K+].[OH-],,test
US20100130538A1,Cn1cc2c([C@@H]3C[C@H]3CO)c(F)ccc2n1.O=C1NC(=O)c2ccccc21>>Cn1cc2c([C@@H]3C[C@H]3CN3C(=O)c4ccccc4C3=O)c(F)ccc2n1,,C1CCOC1,Cc1ccccc1,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06432993B1,Cn1c(COc2ccc(CC3SC(=O)N(C(c4ccccc4)(c4ccccc4)c4ccccc4)C3=O)cc2)nc2ccc(Oc3ccc(C#N)cc3)cc21>>Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccc(Oc3ccc(C#N)cc3)cc21,,CC(=O)O,,,,test
US20090048276A1,N#Cc1ccc(N)cc1Cl.O=C(Oc1c(Cl)cc(Cl)cc1Cl)C(C(=O)Oc1c(Cl)cc(Cl)cc1Cl)c1ccccc1>>N#Cc1cc2c(O)c(-c3ccccc3)c(=O)[nH]c2cc1Cl,,CCOCC,,,,test
US06175007B1,O=Cc1ccc(Cl)cc1Cl.O=[N+]([O-])O>>O=Cc1cc([N+](=O)[O-])c(Cl)cc1Cl,,O=S(=O)(O)O,,,,test
US20030186969A1,CCOC(=O)CNCc1cc(Cl)ccc1[N+](=O)[O-].O=C(Cl)c1ccc(Cl)cc1>>CCOC(=O)CN(Cc1cc(Cl)ccc1N)C(=O)c1ccc(Cl)cc1,[Pd],CCOC(C)=O,ClCCl,CCN(CC)CC,[H][H],test
US20090264445A1,COC(=O)C(CCC(C)(C)C)N1CC(Oc2ccccc2Cl)=CC1=O>>CC(C)(C)CCC(C(=O)O)N1CC(Oc2ccccc2Cl)=CC1=O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20090005356A1,O=P(Cl)(Cl)Cl.[O-][n+]1cc(Br)cc2cc[nH]c21>>Clc1c(Br)cnc2[nH]ccc12,,CN1CCCC1=O,,,,test
US20080146637A1,CC(C)(C)OC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1NC(=O)OC(C)(C)C.O=S(=O)(c1ccccc1Cl)C(F)(F)F>>CC(C)(C)OC(=O)Nc1ccc(-c2ccccc2S(=O)(=O)C(F)(F)F)cc1NC(=O)OC(C)(C)C,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20070027185A1,COC(=O)c1ccc(N2CCCC2)cc1OC1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(Oc2cc(N3CCCC3)ccc2C(=O)O)CC1,,C1CCOC1,,CO,[Li+].[OH-],test
US20090270402A1,CC(C)c1nnc2ccc(CC(=O)c3ccc(F)cc3F)nn12.O=C1CCC(=O)N1Br>>CC(C)c1nnc2ccc(C(=O)C(=O)c3ccc(F)cc3F)nn12,,CS(C)=O,,,,test
US20080242665A1,CCCC[Sn](CCCC)(CCCC)c1cncs1.CS(=O)(=O)N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1>>CS(=O)(=O)N1CCN(Cc2cc3nc(-c4cncs4)nc(N4CCOCC4)c3s2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(=O)N(C)C,,,,test
US20040077690A1,Nc1ccc(Cl)cn1.O=C(O)c1cc(Cl)cc(Cl)c1[N+](=O)[O-]>>O=C(Nc1ccc(Cl)cn1)c1cc(Cl)cc(Cl)c1[N+](=O)[O-],CN(C)C=O,ClCCl,ClCCl,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20070053831A1,CN(C)/C=C/C(=C(C#N)C#N)c1ccc2cc(N(C)C)ccc2c1.Cl>>CN(C)c1ccc2cc(-c3ccnc(Cl)c3C#N)ccc2c1,,CC(C)O,,,,test
US20020173665A1,O=C(CCCOc1ccccc1)N[C@H]1CCCc2ccccc21>>c1ccc(OCCCCN[C@H]2CCCc3ccccc32)cc1,,C1CCOC1,,,,test
US20020198376A1,CC(C)(C)OC(=O)C(OCc1ccccc1)[C@@H](N)Cc1ccccc1.Cl>>Cl.N[C@H](COCc1ccccc1)Cc1ccccc1,,CO,,,,test
US20140378483A1,COC(=O)Cn1c(=O)[nH]c2ccc(C(=O)c3c(C)c(-c4ccc(OCCOCCOCCOCCOc5ccc(-c6c(C)c(C(=O)c7ccc8[nH]c(=O)n(CC(=O)[O-])c(=O)c8c7)n7ccccc67)cc5)cc4)c4ccccn34)cc2c1=O>>Cc1c(-c2ccc(OCCOCCOCCOCCOc3ccc(-c4c(C)c(C(=O)c5ccc6[nH]c(=O)n(CC(=O)O)c(=O)c6c5)n5ccccc45)cc3)cc2)c2ccccn2c1C(=O)c1ccc2[nH]c(=O)n(CC(=O)O)c(=O)c2c1,,CN1CCCC1=O,,Cl,[Na+].[OH-],test
US20050101593A1,COP(=O)(CC(=O)CCCCc1ccc2c(n1)NCCCC2)OC.COc1ncc(C=O)cn1>>COc1ncc(C=CC(=O)CCCCc2ccc3c(n2)NCCCC3)cn1,,C1CCOC1,O,[Na+].[OH-],,test
US20150181867A1,BrCc1ccccc1.C=C[C@H](O)[C@@H](CCC(C)C)[C@H](C)OCc1ccc(OC)cc1>>C=C[C@H](OCc1ccccc1)[C@@H](CCC(C)C)[C@H](C)OCc1ccc(OC)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20060111375A1,CCCOC(=O)c1cc(-c2ccc(F)cc2F)ccc1O.COc1cc2nccc(Cl)c2cc1OC>>CCCOC(=O)c1cc(-c2ccc(F)cc2F)ccc1Oc1ccnc2cc(OC)c(OC)cc12,CN(C)c1ccncc1,Clc1ccccc1Cl,,,,test
US20080234237A1,CN(C)CCN1CCCc2ccccc21.O=[N+]([O-])O>>CN(C)CCN1CCCc2ccc([N+](=O)[O-])cc21,,O,,O=S(=O)(O)O,[Na+].[OH-],test
US20010021714A1,CCc1sc2ccccc2c1S(=O)(=O)Cl.Cc1noc(N)c1Br>>CCc1sc2ccccc2c1S(=O)(=O)Nc1onc(C)c1Br,,C1CCOC1,,[H-].[Na+],,test
US05643878,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H]1C[C@@H](Cc2ccc(F)cc2F)C(=O)O1.O>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)[C@@H](O)C[C@@H](Cc1ccc(F)cc1F)C(=O)O,,COCCOC,O,[Li+].[OH-],,test
US20160152543A1,Cc1c([N+](=O)[O-])cc(C2CC2)c(-c2ccc3c(c2)CCCO3)c1C(COC(=O)C(C)(C)C)OC1CC1>>Cc1c([N+](=O)[O-])cc(C2CC2)c(-c2ccc3c(c2)CCCO3)c1C(CO)OC1CC1,,C1CCOC1,CO,O,[Na+].[OH-],test
US05274116,O=C(c1cccs1)c1cccn1N1C(=O)c2ccccc2C1=O>>Nn1cccc1C(=O)c1cccs1,,CN(C)C=O,O,CN,,test
US20070004705A1,CCN(CC)S(F)(F)F.CCOC(=O)c1ccc(N2CCC(O)CC2)cc1>>CCOC(=O)c1ccc(N2CCC(F)CC2)cc1,,ClCCl,,,,test
US20050143588A1,COc1cc(-c2coc3c(C)c(OC(C)=O)ccc3c2=O)ccc1OC(C)=O>>COc1cc(C2COc3c(ccc(OC(C)=O)c3C)C2O)ccc1OC(C)=O,[Pd],CO,,,,test
US20130338173A1,CCOC(Cc1c(Cl)ncnc1N[C@@H]1C[C@H](CO)[C@@H](O)[C@H]1O)OCC>>OC[C@H]1C[C@@H](n2ccc3c(Cl)ncnc32)[C@H](O)[C@@H]1O,,C1COCCO1,,Cl,,test
US20090048230A1,N#CC(=CO)c1ccccc1.NNc1ccccn1>>Nc1c(-c2ccccc2)cnn1-c1ccccn1,,CCO,,CC(=O)O,,test
US20140350032A1,CC(C)C1=C2[C@H]3CC[C@H]4[C@@](C)(CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(=O)OC(C)(C)C)CC[C@@]54C)[C@]3(C)CC[C@@]2(/C=C/C(=O)NCC2CCCCC2)CC1=O>>CC(C)C1=C2[C@H]3CC[C@H]4[C@@](C)(CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(=O)O)CC[C@@]54C)[C@]3(C)CC[C@@]2(/C=C/C(=O)NCC2CCCCC2)CC1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100081673A1,N#Cc1ccc(Br)c(C=O)c1.NCc1ccccc1>>N#Cc1ccc(Br)c(CNCc2ccccc2)c1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US04497817,CI.Nc1ccc2c(c1)sc1nc(-c3ccccc3)cn12>>CNc1ccc2c(c1)sc1nc(-c3ccccc3)cn12,,CCO,,,,test
US05342846,Cc1c(F)c(F)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1.c1cn(C2CCNC2)nn1>>Cc1c(F)c(N2CCC(n3ccnn3)C2)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1,,c1ccncc1,,C1CCC2=NCCCN2CC1,Cl,test
US20040014962A1,C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(SC3CN(c4nc(C(=O)N[C@H]5CCN(C(=O)OCc6ccc([N+](=O)[O-])cc6)C5)co4)C3)[C@H](C)[C@H]12>>C[C@@H](O)[C@H]1C(=O)N2C(C(=O)O)=C(SC3CN(c4nc(C(=O)N[C@H]5CCNC5)co4)C3)[C@H](C)[C@H]12,,C1CCOC1,,,,test
US20120229884A1,CI.C[Si](C)(C)O[Si](CCCN(CCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)CCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C>>C[N+](CCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)(CCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)CCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C.[I-],,CC(C)=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20130217666A1,COC(=O)c1nc2c(s1)CCOc1ccc(Br)cc1-2.O=C1CCC(=O)N1Br>>COC(=O)c1nc2c(s1)C(Br)COc1ccc(Br)cc1-2,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20090099205A1,CC(C)(C)OC(=O)N[C@@H](CN1C(=O)c2ccccc2C1=O)c1ccccc1>>CC(C)(C)OC(=O)N[C@@H](CN)c1ccccc1,,CCO,,NN,O,test
US20110105748A1,CCOC(=O)C(Cc1ccc([N+](=O)[O-])cc1)OC(C)C>>CCOC(=O)C(Cc1ccc(N)cc1)OC(C)C,,CCOC(C)=O,,,,test
US20140171429A1,COc1cc(N2CCN(C)CC2)ccc1N.O=c1[nH]cnc2cc(Cl)nc(Cl)c12>>COc1cc(N2CCN(C)CC2)ccc1Nc1nc(Cl)cc2nc[nH]c(=O)c12,,C1COCCO1,,CCN(CC)CC,,test
US20110059943A1,CC(=O)CN=[N+]=[N-].CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(N=C=S)nc21>>CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(Nc3ncc(C)o3)nc21,,C1COCCO1,CCOC(C)=O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US07368471B2,CC(C)(C)c1ccc(B(O)O)cc1.CC(C)(C)c1ccc(Cn2ccc3cc(Br)ccc32)cc1>>CC(C)(C)c1ccc(Cn2ccc3cc(-c4ccc(C(C)(C)C)cc4)ccc32)cc1,,O,,,,test
US04323573,CC(=O)OCCOCOC(C)=O.Clc1nc(Cl)c2[nH]cnc2n1>>CC(=O)OCCOCn1cnc2c(Cl)nc(Cl)nc21,,CCOCC,,,,test
US20080227812A1,CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12.O=CC1CC1>>CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(NCC6CC6)CC5)c(OC)cc34)ccc12,,CCO,,[BH4-].[Na+],,test
US20100317659A1,Cc1cc(N)n[nH]1.Fc1ccc(C(F)(F)c2nc(Cl)c3ccc(F)cc3n2)cc1>>Cc1cc(Nc2nc(C(F)(F)c3ccc(F)cc3)nc3cc(F)ccc23)n[nH]1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,[I-].[K+],test
US20050038104A1,COc1cccc(F)c1C#N.O=C=O>>COc1ccc(C(=O)O)c(F)c1C#N,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US04782011,BrCc1ccccc1.Cc1cc(C)c(O)c(C(CC(C)CC(C)(C)C)c2cc(C)cc(C)c2O)c1>>CC1=CC(=C(CC(C)CC(C)(C)C)c2cc(C)cc(C)c2OCc2ccccc2)C(O)C(C)=C1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050197350A1,CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.Cc1cc(N[C@@H]2CC[C@H](N)CC2)nc2ccccc12.F[P-](F)(F)(F)(F)F.O=C(O)COc1ccc(OC(F)(F)F)cc1>>Cc1cc(N[C@@H]2CC[C@H](NC(=O)COc3ccc(OC(F)(F)F)cc3)CC2)nc2ccccc12.O=C(O)C(F)(F)F,,CS(C)=O,,CN(C)C=O,,test
US20130116285A1,CC(C)COc1ccc(O)cn1.N#Cc1ccc(F)c(Br)c1>>CC(C)COc1ccc(Oc2ccc(C#N)cc2Br)cn1,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20090298807A1,COC(=O)c1nc(C(C)C)sc1C>>Cc1sc(C(C)C)nc1C(=O)O,,CO,O,[Li+].[OH-],,test
US04900744,CCOC(=O)CCCCCCCCCCBr.Sc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1>>CCOC(=O)CCCCCCCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20150252022A1,C[C@H]1C[C@H](Cn2ccc3cc(-c4cnn(C5CCCCO5)c4)ccc32)CN1C(=O)CCc1ccccc1>>C[C@H]1C[C@H](Cn2ccc3cc(-c4cn[nH]c4)ccc32)CN1C(=O)CCc1ccccc1,,CO,ClCCl,O=C([O-])O.[Na+],,test
US05532358,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ncccc1N>>COc1ncccc1NC(=O)OC(C)(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US03998834,CC(Br)C(=O)c1ccccc1.CCC(=O)N(c1ccccc1)C1(COC)CCNCC1>>CCC(=O)N(c1ccccc1)C1(COC)CCN(C(C)C(=O)c2ccccc2)CC1,,CC(=O)CC(C)C,,CC(C)NC(C)C,,test
US05866594,COC(=O)C(N=[N+]=[N-])=C(c1ccccc1)c1cc(OC)ccc1OC>>COC(=O)c1cc2c(OC)ccc(OC)c2[nH]1,,Cc1ccccc1C,,,,test
US05387585,CCOC(=O)c1ncn2c1CN(Cc1ccc(OC)cc1OC)C(=O)c1sccc1-2>>CCOC(=O)c1ncn2c1CNC(=O)c1sccc1-2,,O=C(O)C(F)(F)F,,,,test
US04364875,C=CCN.N#Cc1ccc(Oc2ccc([N+](=O)[O-])c(Oc3ccccc3)c2Cl)cc1>>C=CCNc1c([N+](=O)[O-])ccc(Oc2ccc(C#N)cc2)c1Cl,,C1COCCO1,,,,test
US20040138063A1,COC(=O)C(C)Oc1ncccc1[N+](=O)[O-]>>COC(=O)C(C)Oc1ncccc1N,O=[Pt],CCO,,,,test
US20080269219A1,CCOC(=O)c1ncc[nH]1.COc1ccccc1OCCCc1oc(Cl)nc1-c1ccc(Cl)cc1>>CCOC(=O)c1nccn1-c1nc(-c2ccc(Cl)cc2)c(CCCOc2ccccc2OC)o1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080125468A1,COc1nnnc(OC)c1Cl.NCCC(=O)O.O=C(O)c1ccc(/C=C\C(CCC(F)(F)F)c2ccc(-c3ccc(C(F)(F)F)cc3)nc2)cc1>>COC(=O)CCNC(=O)c1ccc(/C=C\C(CCC(F)(F)F)c2ccc(-c3ccc(C(F)(F)F)cc3)nc2)cc1,,ClCCl,O,CN1CCOCC1,Cl,test
US20050182139A1,CSc1ccc([C@H]2OC(c3ccccc3)=N[C@@H]2CO)cc1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1ccc([C@H]2OC(c3ccccc3)=N[C@@H]2CO)cc1,,ClCCl,,,,test
US20030092677A1,CC(C)(C)OC(=O)Nc1ccc(-c2ccc(F)cc2)cc1NC(=O)CC(=O)c1cccc([N+](=O)[O-])c1>>O=C1CC(c2cccc([N+](=O)[O-])c2)=Nc2ccc(-c3ccc(F)cc3)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070232659A1,CC(=O)OC(C)=O.CC1(C)CC(Nc2cccc(Br)n2)CC(C)(C)N1>>CC(=O)N(c1cccc(Br)n1)C1CC(C)(C)NC(C)(C)C1,,ClCCl,,[Na+].[OH-],,test
US20020002152A1,C=CCOc1cccc(C(=O)OC)c1.C[N+]1([O-])CCOCC1.O=[Os](=O)(=O)=O>>COC(=O)c1cccc(OCC(O)CO)c1,O=[Os](=O)(=O)=O,O,,CC(C)=O,,test
US04536507,N#Cc1ccc2c(c1)Sc1ccccc1CC2=O.O=CO>>O=Cc1ccc2c(c1)Sc1ccccc1CC2=O,[Ni],,,,,test
US04816582,CCOC(=O)/C(=N\O)c1csc(N)n1.Cn1nnnc1CCl>>CCOC(=O)/C(=N\OCc1nnnn1C)c1csc(N)n1,,CC#N,CCOC(C)=O,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20090306133A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CN)CC1.CCOC(=O)Cl>>CCOC(=O)NC[C@@H]1CC[C@@H](CNC(=O)OC(C)(C)C)CC1,,ClCCl,,,,test
US04696990,COc1ccc(C=CC(=O)Cl)cc1.O=C(O)c1ccc(O)cc1>>COc1ccc(C=CC(=O)Oc2ccc(C(=O)O)cc2)cc1,CN(C)c1ccncc1,c1ccncc1,,CCN(C(C)C)C(C)C,,test
US20020040146A1,COc1ccc(CS[C@@H]2C[C@@H](CO)N(S(C)(=O)=O)C2)cc1.Oc1ccccc1>>COc1ccc(CS[C@@H]2C[C@@H](COc3ccccc3)N(S(C)(=O)=O)C2)cc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080045525A1,FC(F)(F)c1cccnc1N1CCN(c2cc(Cl)nc(N3CCOCC3)n2)CC1.Fc1ccc2c(c1)CCN2>>Fc1ccc2c(c1)CCN2c1cc(N2CCN(c3ncccc3C(F)(F)F)CC2)nc(N2CCOCC2)n1,,CCOC(C)=O,,,,test
US20160060257A1,COc1ccc(F)cc1-c1ccnc2c1cc(C1=CCN(C(=O)OC(C)(C)C)C1)n2S(=O)(=O)c1ccccc1>>COc1ccc(F)cc1-c1ccnc2c1cc(C1=CCNC1)n2S(=O)(=O)c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060160788A1,CNS(=O)(=O)c1ccc(OC2CCCC2)c(C(=O)OC)c1>>CNS(=O)(=O)c1ccc(OC2CCCC2)c(C(=O)O)c1,,C1CCOC1,,[Na+].[OH-],,test
US04243609,CCCCCCCCCCCCCCCCNc1ccc(C(=O)Cl)c(F)c1.CCOC(=O)CC(C)=O>>CCCCCCCCCCCCCCCCNc1ccc(C(=O)C(C(C)=O)C(=O)OCC)c(F)c1,,COCCOC,,Cl,[H-].[Na+],test
US20120309739A1,COCCNc1nc(OC)c2c(-c3ccccc3)c(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)oc2n1>>COCCNc1nc(OC)c2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)oc2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060211720A1,CC(=O)OC(C)=O.CCc1ccc(N)cc1.O=[N+]([O-])O>>CCc1ccc(NC(C)=O)c([N+](=O)[O-])c1,,CCOC(C)=O,,,,test
US20100113441A1,CCOC(=O)c1cn2c(NCCNc3ccc(C#N)cn3)nc(Cl)cc2n1.OB(O)c1ccc(Cl)cc1Cl>>N#Cc1ccc(NCCNc2nc(-c3ccc(Cl)cc3Cl)cc3nc(C(=O)O)cn23)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20050227959A1,CN(CCc1ccc(F)cc1)S(=O)(=O)c1csc(C(=O)CBr)c1.CNC>>CN(C)CC(=O)c1cc(S(=O)(=O)N(C)CCc2ccc(F)cc2)cs1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US05919824,CC(C)(C)OC(=O)NCC(=O)O.Nc1ccccc1OCc1ccccc1>>CC(C)(C)OC(=O)NCC(=O)Nc1ccccc1OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20030168970A1,CC(=O)c1ccc(B(O)O)cc1.CC1(C)CC2(CC(C)(C)c3ccc(OS(=O)(=O)C(F)(F)F)cc32)c2cc(OS(=O)(=O)C(F)(F)F)ccc21.CCO.Cc1ccccc1>>CC(=O)c1ccc(-c2ccc3c(c2)C2(CC3(C)C)CC(C)(C)c3ccc(-c4ccc(C(C)=O)cc4)cc32)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US20100069367A1,CC(C)(CO)NC(=O)c1cn(-c2ccc(Br)cc2Cl)c(-c2ccccc2Cl)n1.CS(=O)(=O)c1cccc(B(O)O)c1>>CC(C)(CO)NC(=O)c1cn(-c2ccc(-c3cccc(S(C)(=O)=O)c3)cc2Cl)c(-c2ccccc2Cl)n1,,CCOC(C)=O,O,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20050227975A1,CC(=O)c1cc(OCc2ccccc2)cc2c1CCC(=O)N2>>CC(=O)c1cc(OCc2ccccc2)cc2[nH]c(=O)ccc12,,C1COCCO1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20060052597A1,N#Cc1ccc(F)cc1C(F)(F)F.OCCCN1CCCCC1>>N#Cc1ccc(OCCCN2CCCCC2)cc1C(F)(F)F,,C1CCOC1,CCOC(C)=O,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20120165353A1,CCCCc1nc(C)n(-c2ncc(OC)cn2)c(=O)c1Cc1ccc(-c2ccccc2C#N)nc1.C[Si](C)(C)N=[N+]=[N-]>>CCCCc1nc(C)n(-c2ncc(OC)cn2)c(=O)c1Cc1ccc(-c2ccccc2-c2nnn[nH]2)nc1,,Cc1ccccc1,,CCCC[Sn](=O)CCCC,,test
US20070185133A1,CCN(CC)C(=O)c1ccc(OC)cc1SC>>COc1ccc2c(c1)SCC2=O,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20090005410A1,COC(=O)C(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-n2nnc3ncccc32)cc1>>CC(C)(CO)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-n2nnc3ncccc32)cc1,,ClCCl,,CC(C)C[Al+]CC(C)C.[H-],,test
US04827020,C#CCCl.COC(=O)CNC(=O)OC>>C#CCN(CC(=O)OC)C(=O)OC,,CN(C)C=O,,[H-].[Na+],,test
US20090326009A1,COC(=O)c1cc([N+](=O)[O-])ccc1-c1ccccc1OCc1ccccc1>>Nc1ccc2c(c1)c(=O)oc1ccccc12,[Pd],C1CCOC1,CO,,,test
US20060142265A1,Cc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)CNC(C)(C)C(=O)N3)oc2ccccc12.Cl>>Cc1c(CN(C)C(=O)/C=C/c2cnc3c(c2)CNC(C)(C)C(=O)N3)oc2ccccc12.Cl,,CCOCC,ClCCl,,,test
US20060046980A1,CO.COc1ccc(Oc2c(C)cc(CC(=O)O)cc2C)cc1C(C)C>>COC(=O)Cc1cc(C)c(Oc2ccc(OC)c(C(C)C)c2)c(C)c1,,CO,,CC(=O)Cl,,test
US20070244104A1,C#CC1(N)CCCCC1.CN=C=O>>C#CC1(NC(=O)NC)CCCCC1,,CC#N,,CCN(CC)CC,,test
US04440940,CCCCCCCCCCCCC=CN(C(=O)C(F)(F)F)c1ccccc1C(=O)Cl.CCOC(=O)[C@H](C)N>>CCCCCCCCCC=CCCCNc1ccccc1C(=O)N[C@@H](C)C(=O)O,,CCOCC,,CCN(CC)CC,,test
US20080269220A1,COC(=O)c1ccc(CN2CCC(O)CC2)c(OC(C)C)c1.Cc1cccc(C)c1O>>COC(=O)c1ccc(CN2CCC(Oc3c(C)cccc3C)CC2)c(OC(C)C)c1,,C1CCOC1,CCOCC,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20070015784A1,COc1ccc(C(=O)N2CCC3(CC2)N[C@@H](CCSC)C(=O)N3Cc2ccccc2)c(OC)c1.C[Si](C)(C)Cl>>COc1ccc(C(=O)N2CCC3(CC2)N[C@@H](CCSC)C(=O)N3Cc2ccccc2)c(OC)c1.Cl,,CCC(C)=O,,O,,test
US20150329542A1,Fc1cc(-c2cc3c(cn2)c(I)nn3C2CCCCO2)c(CC(F)(F)F)cc1OCc1ccccc1.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1cc2c(I)nn(C3CCCCO3)c2cc1-c1cc(F)c(OCc2ccccc2)cc1CC(F)(F)F,,ClCCl,,,,test
US20110083984A1,CC(C)(C)[Si](C)(C)Cl.OCC1CNCCO1>>CC(C)(C)[Si](C)(C)OCC1CNCCO1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20030187001A1,COc1cc(-c2cn(C3CCCC3)c3ncnc(Cl)c23)ccc1NC(=O)OC(C)(C)C>>COc1cc(-c2cn(C3CCCC3)c3ncnc(Cl)c23)ccc1N,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130116234A1,CCOC(=O)c1c(N(C)C)nc2c(N(C)C)cc(Cl)cc2c1Cc1ccccc1Cl>>CN(C)c1nc2c(N(C)C)cc(Cl)cc2c(Cc2ccccc2Cl)c1C(=O)O,,CCO,,[Na+].[OH-],,test
US05410630,CCCCOc1ccc(C=O)cc1.Nc1ccccc1>>CCCCOc1ccc(C=Nc2ccccc2)cc1,Cc1ccc(S(=O)(=O)O)cc1,O,,Cc1ccccc1,,test
US20090131436A1,Clc1ncc(Cl)c(Cl)n1.Nc1cccc2c1SCCC2>>Clc1ncc(Cl)c(Nc2cccc3c2SCCC3)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080221180A1,CC(=O)NCCN.CC(=O)Nc1nc(C)c(-c2ccc(S(=O)(=O)Cl)s2)s1>>CC(=O)NCCNS(=O)(=O)c1ccc(-c2sc(NC(C)=O)nc2C)s1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20160002180A1,BrCc1ccccc1.Brc1ncn[nH]1>>Brc1ncnn1Cc1ccccc1,,CCOC(C)=O,,CO,C[O-].[Na+],test
US20110092547A1,COC(=O)[C@@H]1CC[C@@H](Oc2ccc([N+](=O)[O-])cn2)C1>>COC(=O)[C@@H]1CC[C@@H](Oc2ccc(N)cn2)C1,[Pd],CO,,,,test
US20120165343A1,CCOC(=O)CCNC(=O)c1ccc(NC(c2cnc(-c3ccc(C(F)(F)F)cc3)nc2)C2CCCCC2)nc1>>O=C(O)CCNC(=O)c1ccc(NC(c2cnc(-c3ccc(C(F)(F)F)cc3)nc2)C2CCCCC2)nc1,,CO,,C1CCOC1,[Li+].[OH-],test
US20130331561A1,CCCCCc1ccc(-c2cc3cn(C4CC(O)C(CO[Si](C)(C)C(C)(C)C)O4)c(=O)nc3o2)cc1.O=C(Cl)CCl>>CCCCCc1ccc(-c2cc3cn([C@H]4C[C@H](OC(=O)CCl)[C@@H](CO[Si](C)(C)C(C)(C)C)O4)c(=O)nc3o2)cc1,CN(C)c1ccncc1,ClCCl,,,,test
US20060287341A1,CSc1nc(-c2ccc(Cl)cc2)c(-c2ccccc2)c2n[nH]c(=O)n12.FC(F)(F)c1ccc(CBr)cc1>>CSc1nc(-c2ccc(Cl)cc2)c(-c2ccccc2)c2nn(Cc3ccc(C(F)(F)F)cc3)c(=O)n12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050171109A1,COc1ccc(Br)c2c1C(C)(C)CC(O)(C(F)(F)F)C2Nc1cccc2[nH]ncc12>>CC1(C)CC(O)(C(F)(F)F)C(Nc2cccc3[nH]ncc23)c2c(Br)ccc(O)c21,,CCOC(C)=O,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20150218181A1,CI.CN(C)S(=O)(=O)c1ccc(N2C(=O)c3ccccc3C2=O)c(O)c1>>COc1cc(S(=O)(=O)N(C)C)ccc1N1C(=O)c2ccccc2C1=O,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20120330024A1,CCOC(=O)CN.CCOC(=O)CN=C=S>>CCOC(=O)CN1C(=O)CNC1=S,,CC#N,,CCN(CC)CC,Cl,test
US20080064715A1,O=C(c1ccccc1)c1cc2ccnc(Cl)c2[nH]1>>O=C(c1ccccc1)c1cc2ccncc2[nH]1,Cl[Pd]Cl,CN(C)C=O,ClCCl,CCN(CC)CC,,test
US20030144285A1,Brc1ccccn1.CCCCC1CCN(CCCC(=O)OC)CC1>>CCCCC1CCN(CCCC(=O)c2ccccn2)CC1,,ClCCl,,[Li]CCCC,,test
US20120289501A1,Nc1ncnc2c1c(I)cn2[C@@H]1C[C@H](CN2C[C@@H]3C[C@H]2CS3)C1.O=S1(=O)CC2CC1CN2>>Nc1ncnc2c1c(I)cn2[C@@H]1C[C@H](CN2C[C@@H]3C[C@H]2CS3(=O)=O)C1,,CO,,,,test
US20120101124A1,CCOC(=O)COc1ccc(-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)c2occc12>>CC(C)Oc1ccc(-c2nc(-c3ccc(OCC(=O)O)c4ccoc34)no2)cc1Cl,,CCO,,Cl,[Na+].[OH-],test
US20150252036A1,CCOC(=O)C(C)Cc1ccccn1>>CC(Cc1ccccn1)C(=O)O,,C1COCCO1,O,[Li+].[OH-],,test
US05750524,O=C1CCC(=O)O1.O=S(=O)(NCC1Cc2ccccc2C1)c1ccc(Cl)cc1>>O=C(O)CCC(=O)c1ccc2c(c1)CC(CNS(=O)(=O)c1ccc(Cl)cc1)C2,,CC(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20070213361A1,CCc1nc2c(C)cc(C)nc2n1Cc1ccc(C(O)c2ccccc2)cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CCc1nc2c(C)cc(C)nc2n1Cc1ccc(C(N=[N+]=[N-])c2ccccc2)cc1,,Cc1ccccc1,,C1CCC2=NCCCN2CC1,,test
US04273932,CCOC(=O)c1cnc2c(c1O)C(=NO)CCC2>>O=C(O)c1cnc2c(c1O)C(=NO)CCC2,,O,,Cl,[Na+].[OH-],test
US20100317657A1,Cc1nn(C)cc1Nc1c(N)cnc2ccc(Br)cc12.O=C(Cl)OC(Cl)(Cl)Cl>>Cc1nn(C)cc1-n1c(=O)[nH]c2cnc3ccc(Br)cc3c21,,ClCCl,,,,test
US20090312383A1,CCC(CC)c1ccc(C(F)(F)F)c2nc(Cl)n(C)c12.Cc1cc(Cl)cc(Cl)c1O>>CCC(CC)c1ccc(C(F)(F)F)c2nc(Oc3c(C)cc(Cl)cc3Cl)n(C)c12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20100216746A1,C=Cc1cc(Cl)c(C(=O)OC)[nH]1.OO>>COC(=O)c1[nH]c(CCO)cc1Cl,,C1CCOC1,,B1C2CCCC1CCC2,[Na+].[OH-],test
US20110033417A1,Cc1cc2c(cc1F)[nH]c1c(=O)oc3ncccc3c12.N#Cc1ccc(F)c(CBr)c1>>Cc1cc2c3c4cccnc4oc(=O)c3n(Cc3cc(C#N)ccc3F)c2cc1F,,CCOC(C)=O,CN(C)C=O,,,test
US20040058903A1,O=[N+]([O-])c1ccc(OCCCc2ccccn2)nc1>>Nc1ccc(OCCCc2ccccn2)nc1,[Fe],CCO,O,[Cl-].[NH4+],,test
US05939422,N.S=C=NCc1ccccc1>>NC(=S)NCc1ccccc1,,C1CCOC1,,O,,test
US20020052322A1,COC(=O)[C@@H](N)Cc1c[nH]c2ccccc12.C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)O>>COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)Cc1cc(F)cc(F)c1,,CO,ClC(Cl)Cl,Cl,,test
US05807857,CC(=O)OC(C)=O.O=[N+]([O-])c1ccc(CCBr)cc1>>CC(=O)Nc1ccc(CCBr)cc1,O=[Pt]=O,CCO,,,,test
US05047411,CC(=O)Cl.Cc1c(CCc2ccc3nc(N)oc3c2)nc2cc(O)ccn12>>CC(=O)Oc1ccn2c(C)c(CCc3ccc4nc(N)oc4c3)nc2c1,,C1CCOC1,ClCCl,CCN(CC)CC,CCOC(C)=O,test
US20140128611A1,COC(=O)C1(Cc2ccc(Cl)cc2)CCC(C)(COS(=O)(=O)c2ccc(C)cc2)C1=O>>Cc1ccc(S(=O)(=O)OCC2(C)CCC(Cc3ccc(Cl)cc3)C2=O)cc1,,O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100041891A1,Brc1cccc2cn[nH]c12.FC(F)(F)c1cccc(CBr)c1>>FC(F)(F)c1cccc(Cn2cc3cccc(Br)c3n2)c1,,O,,CN(C)C=O,,test
US20030060631A1,C[C@H](c1ccccc1)N1CCC(CC2(NC(=O)OC(C)(C)C)CC2)C1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)NC1(CC2CCN(C(=O)OCc3ccccc3)C2)CC1,,ClCCl,,,,test
US20160168129A1,NCc1ccccc1.O=C(OCc1ccccc1)C(Br)CCBr>>O=C(OCc1ccccc1)C1CCN1Cc1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060025589A1,CCOC(=O)C(C)Br.NCc1ccc(Oc2ccccc2)cc1>>CCOC(=O)[C@H](C)NCc1ccc(Oc2ccccc2)cc1,,C1COCCO1,,,,test
US20130281428A1,CC1(C)OB(c2cccnc2N)OC1(C)C.O=C1CCC(=O)N1Br>>CC1(C)OB(c2cc(Br)cnc2N)OC1(C)C,,CN(C)C=O,,O,,test
US06451804B1,CS(=O)(=O)OS(C)(=O)=O.C[Si](C)(C)CCOCN1C(=O)N(c2ccccc2Cl)Cc2cnc(N[C@@H]3CC[C@@H](N)CC3)nc21>>C[Si](C)(C)CCOCN1C(=O)N(c2ccccc2Cl)Cc2cnc(N[C@@H]3CC[C@@H](NS(C)(=O)=O)CC3)nc21,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20040171099A1,BrCc1ccccn1.N#Cc1nc2ccc(O)cc2s1>>N#Cc1nc2ccc(OCc3ccccn3)cc2s1,,CC(C)=O,,Br,O=C([O-])[O-].[K+].[K+],test
US20140275172A1,CS(=O)(=O)Cl.Cc1cc2cc(F)cc(CO)c2o1>>Cc1cc2cc(F)cc(COS(C)(=O)=O)c2o1,,ClCCl,ClCCl,CCN(CC)CC,,test
US20150284418A1,CC(C)(Br)C(=O)Br.Cc1cccc(C)c1O>>Cc1cc2c(c(C)c1O)CC(C)C2=O,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US05264578,C#Cc1ccc2c(c1)C(CCCC)(CCCC)CCS2.CCN(CC)CC.CCOC(=O)c1ccc(I)nc1>>CCCCC1(CCCC)CCSc2ccc(C#Cc3ccc(C(=O)OCC)cc3)cc21,[Cu]I,,,,,test
US20020031816A1,CC(=O)Cl.O=C1Cc2ccccc2N1CC(F)(F)F>>CC(=O)c1ccc2c(c1)CC(=O)N2CC(F)(F)F,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US06150524,COCOc1ccc2c3c1O[C@H]1[C@@H](OC(=O)CCCc4ccc(OC)cc4)C=C[C@H]4[C@@H](C2)N(C)CC[C@@]341>>COCOc1ccc2c3c1O[C@H]1[C@@H](OC(=O)CCCc4ccc(OC)cc4)CC[C@H]4[C@@H](C2)N(C)CC[C@@]341,[Pd],CO,,,,test
US20130085148A1,CC(O)c1noc(-c2ccc(F)cc2)n1>>CC(=O)c1noc(-c2ccc(F)cc2)n1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05352784,Nc1nc2c(c3c1ncn3CCCO)CCCC2.O=S(Cl)Cl>>Nc1nc2c(c3c1ncn3CCCCl)CCCC2,,CN(C)C=O,,,,test
US20070213339A1,CCOC=C(C(=O)OCC)C(=O)c1cc(F)c(F)c(Cl)c1F.Nc1cccc(CN2CCCCC2)c1>>CCOC(=O)C(=CNc1cccc(CN2CCCCC2)c1)C(=O)c1cc(F)c(F)c(Cl)c1F,,CCO,,,,test
US05840917,BrCc1ccsc1Br.CC(=O)[O-]>>CC(=O)OCc1ccsc1Br,,CC(C)=O,,O,,test
US20130143899A1,CCCS(=O)(=O)Nc1ncc(F)c(I)c1F.C[Si](C)(C)CCOCCl>>CCCS(=O)(=O)N(COCC[Si](C)(C)C)c1ncc(F)c(I)c1F,,CN(C)C=O,,[H-].[Na+],,test
US20140024650A1,CC(C)(C)OC(=O)N[C@H]1COCC[C@@H]1COc1ccc(-n2cc(Cl)cn2)cc1F.Cl>>Cl.N[C@H]1COCC[C@@H]1COc1ccc(-n2cc(Cl)cn2)cc1F,,CCOC(C)=O,Cl,,,test
US20110059942A1,CCNC(=O)c1ncc(-c2ccc(O)cc2)cc1C.CS(=O)(=O)OC1CN(Cc2ccc(C(F)(F)F)cc2)C1>>CCNC(=O)c1ncc(-c2ccc(OC3CN(Cc4ccc(C(F)(F)F)cc4)C3)cc2)cc1C,,CCOC(C)=O,CS(C)=O,CC(C)(C)[O-].[K+],,test
US20070072874A1,CN1CCC(=O)CC1.Nc1ncc(-c2ccc3[nH]ccc3c2)cc1OCc1c(Cl)cccc1Cl>>CN1CC=C(c2c[nH]c3ccc(-c4cnc(N)c(OCc5c(Cl)cccc5Cl)c4)cc23)CC1,,CC(=O)O,,O=C(O)C(F)(F)F,,test
US20070232583A1,CC(C)(C)NS(=O)(=O)c1cccc(-c2cc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)F)n3)ccn2)c1>>NS(=O)(=O)c1cccc(-c2cc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)F)n3)ccn2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070249649A1,Nc1ccc(CS(=O)(=O)N2CCOCC2)cc1.O=C1CCC(=O)N1Br>>Nc1ccc(CS(=O)(=O)N2CCOCC2)cc1Br,,ClCCl,,O=C([O-])O.[Na+],,test
US05342935,CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(O)C(OC)C3)C(C)CCC1=O)C(C)CC2OC.O=[Se]=O>>CCC1C=C(C)C(O)C(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(O)C(OC)C3)C(C)CCC1=O)C(C)CC2OC,,CCO,,,,test
US20080188532A1,Cn1c(C(=O)O)cc2cccc(Br)c21.O=C(Cl)C(=O)Cl>>Cn1c(C(=O)Cl)cc2cccc(Br)c21,,CN(C)C=O,,ClCCl,,test
US20160002208A1,Cl.Cn1nc(C(F)(F)C(F)(F)F)c(C(F)(F)F)c1-n1cnc(-c2cccc(CNC(=O)OC(C)(C)C)c2)c1>>Cl.Cn1nc(C(F)(F)C(F)(F)F)c(C(F)(F)F)c1-n1cnc(-c2cccc(CN)c2)c1,,C1COCCO1,,,,test
US20040209921A1,CC(C)(c1ccc(Cl)cc1)c1cccnc1COS(C)(=O)=O.Cc1cnc(CNCCCCN(C(=O)OC(C)(C)C)C2CC2)c(C)c1>>Cc1cnc(CN(CCCCN(C(=O)OC(C)(C)C)C2CC2)Cc2ncccc2C(C)(C)c2ccc(Cl)cc2)c(C)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20070232607A1,O=[N+]([O-])c1ccc(F)c(Cl)c1.Oc1ccccn1>>O=[N+]([O-])c1ccc(Oc2ccccn2)c(Cl)c1,,O,,[H-].[Na+],,test
US20110136859A1,CC(C)N1C(=O)c2ccc(NCc3ccc(Cl)cc3)cc2C1=O.Cn1cnc(S(=O)(=O)Cl)c1>>CC(C)N1C(=O)c2ccc(N(Cc3ccc(Cl)cc3)S(=O)(=O)c3cn(C)cn3)cc2C1=O,,ClCCl,,c1ccncc1,,test
US20100064450A1,C1COCCN1.C=O.O=Cc1ccc(O)c(O)c1O>>O=Cc1cc(CN2CCOCC2)c(O)c(O)c1O,,CCO,,,,test
US20130039906A1,c1cncc(-c2cc3c(-c4cc[nH]n4)nn(C4CCCCO4)c3cn2)c1>>c1cncc(-c2cc3c(-c4cc[nH]n4)n[nH]c3cn2)c1,,C1COCCO1,Cl,,,test
US20150266848A1,CCC1(CC)O[C@@H](CCOC(=O)C(C)(C)C)[C@H](Cc2ccccc2)O1>>CCC1(CC)O[C@@H](CCO)[C@H](Cc2ccccc2)O1,,CCOC(C)=O,CO,C[O-].[Na+],,test
US20100216788A1,Cc1cc([N+](=O)[O-])ccc1F.O=Cc1cccc(O)c1>>Cc1cc([N+](=O)[O-])ccc1Oc1cccc(C=O)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140349993A1,CC1(C)OCC(CO)O1.Nc1cccc(Cl)n1>>CC1(C)OCC(COc2cccc(N)n2)O1,,C1COCCO1,,[H-].[Na+],,test
US20080262042A1,CN(Cc1c[nH]c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C.N#Cc1ccccc1S(=O)(=O)Cl>>CN(Cc1cn(S(=O)(=O)c2ccccc2C#N)c(-c2cccnc2F)c1F)C(=O)OC(C)(C)C,,C1CCOC1,O,C1COCCOCCOCCOCCO1,[H-].[Na+],test
US20090054405A1,C1CCNCC1.Nc1cc(Br)cnc1Cl.O=S(=O)(Cl)Cl>>O=S(=O)(Nc1cc(Br)cnc1Cl)N1CCCCC1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20030153566A1,COc1ccc(N(Cc2ccc(C)cc2)Cc2ccc(C)cc2)cc1NC(=S)NC(=O)c1ccccc1>>COc1ccc(N(Cc2ccc(C)cc2)Cc2ccc(C)cc2)c2sc(NC(=O)c3ccccc3)nc12,,CCOC(C)=O,ClC(Cl)Cl,BrBr,,test
US20020119961A1,CC(C)(C)OC(=O)N1C2CCC1C(=O)NC2.Fc1ccc(CBr)cc1>>O=C1C2CCC(CN1Cc1ccc(F)cc1)N2C(=O)O,,C1CCOC1,CCOCC,[H-].[Na+],,test
US20080306036A1,CCCCC(=C(c1ccc(OC(=O)C(C)(C)C)cc1)c1ccc(OC(=O)C(C)(C)C)cc1)c1cccc(OCCN(C)C)c1>>CCCCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1cccc(OCCN(C)C)c1,,CO,,C1CCOC1,,test
US05426226,CCCN(CCC)C1CCc2cccc(C(=O)C=CN(C)C)c2C1.N=C(N)N>>CCCN(CCC)C1CCc2cccc(-c3ccnc(N)n3)c2C1,,CCO,,,,test
US20070197448A1,CN(C)S(=O)(=O)CC1(NS(=O)C(C)(C)C)CCCCC1>>CN(C)S(=O)(=O)CC1(N)CCCCC1,,C1COCCO1,CO,Cl,,test
US04125732,CC(C)c1ccc(O)cc1.COC(=O)C(Br)c1ccc(OCC(C)Oc2ccc(F)cc2)cc1>>COC(=O)C(Oc1ccc(C(C)C)cc1)c1ccc(OCC(C)Oc2ccc(F)cc2)cc1,,C1CCOC1,,,,test
US20120190701A1,CC(C)(C)[Si](C)(C)OCc1cccc(CO)c1.CS(=O)(=O)Cl>>CC(C)(C)[Si](C)(C)OCc1cccc(COS(C)(=O)=O)c1,,ClCCl,,CCN(CC)CC,,test
US20050014765A1,COc1cc(OC)cc(N2CCN(C(=O)c3ccn(CCO[Si](C)(C)C(C)(C)C)c3-c3ccccc3)CC2)c1>>COc1cc(OC)cc(N2CCN(C(=O)c3ccn(CCO)c3-c3ccccc3)CC2)c1,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20010014684A1,COCCOCN(c1onc(C)c1Cl)S(=O)(=O)c1c(Cc2cc3c(cc2CCOC(C)=O)OCO3)sc2ncccc12>>Cc1noc(NS(=O)(=O)c2c(Cc3cc4c(cc3CCO)OCO4)sc3ncccc23)c1Cl,,CO,,Cl,,test
US20110076292A1,COC(=O)c1cnc2c(c1)OCCc1nc(-c3ccnn3C(C)C)cn1-2>>CC(C)n1nccc1-c1cn2c(n1)CCOc1cc(C(=O)O)cnc1-2,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20100227859A1,CC(C)(C)c1nc(-c2ccc3c(c2)oc2ccc(S(=O)(=O)Cl)cc23)no1.COC(=O)CN>>COC(=O)CNS(=O)(=O)c1ccc2oc3cc(-c4noc(C(C)(C)C)n4)ccc3c2c1,,ClCCl,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20160264552A1,C=CC(=O)Cl.CC(C)(C)OC(=O)NCc1ccc(N)cc1>>C=CC(=O)Nc1ccc(CNC(=O)OC(C)(C)C)cc1,,C1CCOC1,,,,test
US20090285881A1,CCCCC/C=C\C/C=C\CCCCCCCCOCC(COCCCCCCCC/C=C\C/C=C\CCCCC)(OC)OC>>CCCCC/C=C\C/C=C\CCCCCCCCOCC(=O)COCCCCCCCC/C=C\C/C=C\CCCCC,,C1CCOC1,,Cl,,test
US20090105266A1,CCCNc1cc(C)c(C)cc1[N+](=O)[O-]>>CCCNc1cc(C)c(C)cc1N,[Pd],C1CCOC1,,,,test
US20080312226A1,O=C(Nc1ccc2[nH]c(C(F)(F)F)nc2c1)OCC(Cl)(Cl)Cl.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>O=C(Nc1ccc2[nH]c(C(F)(F)F)nc2c1)N1CCN(c2nc(-c3ccccc3)ns2)CC1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20150291554A1,COC(=C(C#N)C#N)c1ccc(Oc2ccc(F)cc2F)cc1.NNC1CCCN(C(=O)OCc2ccccc2)C1>>N#Cc1c(-c2ccc(Oc3ccc(F)cc3F)cc2)nn(C2CCCN(C(=O)OCc3ccccc3)C2)c1N,,CCO,,CCN(CC)CC,Cl,test
US20020022612A1,COC(=O)C1(C)CCCc2ccc(OC)cc21>>COc1ccc2c(c1)C(C)(C(=O)O)CCC2,,CCO,O,[K+].[OH-],,test
US20050222410A1,CC(C)(C)OC(=O)N1CCNCC1.CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1cnc(Cl)cn1>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1cnc(N2CCN(C(=O)OC(C)(C)C)CC2)cn1,,CC(=O)N(C)C,,,,test
US05238958,COC(=O)Cc1ccc(C(NC(=O)c2ccccc2)C(=O)OC)cc1>>O=C(O)Cc1ccc(CC(=O)O)cc1,,Cl,,,,test
US20100260710A1,C=CCCCCN(C)C(=O)N1CCC(O)CC1C(=O)OC>>C=CCCCCN(C)C(=O)N1CCC(O)CC1C(=O)O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US06057311,C1CCNC1.Cc1cccc(NC(=O)N2CCC(=O)c3ccccc3N(CC(=O)O)C(=O)C2)c1>>Cc1cccc(NC(=O)N2CCC(=O)c3ccccc3N(CC(=O)N3CCCC3)C(=O)C2)c1,,CN(C)C=O,O,ClCCCl,On1nnc2ccccc21,test
US20100256156A1,CCI.Cc1oc(-c2ccc(Cl)cc2)cc1C(=O)O>>CCOC(=O)c1cc(-c2ccc(Cl)cc2)oc1C,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150175594A1,Nc1sc2c(c1-c1nc(C3CC3)no1)CCC(C(F)(F)F)C2.O=C1OC(=O)C2=C1CCC2>>O=C(O)C1=C(C(=O)Nc2sc3c(c2-c2nc(C4CC4)no2)CCC(C(F)(F)F)C3)CCC1,,CO,ClCCl,,,test
US20160002180A1,CC(C)(C)OC(=O)Nc1cccc(Nc2ncn(Cc3ccccc3)n2)c1>>Nc1cccc(Nc2ncn(Cc3ccccc3)n2)c1,,C1COCCO1,,Cl,,test
US04563310,CCOP(C)(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]>>CP(=O)(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-],,Cl,,O,,test
US20060135578A1,CCOP(=O)(CP(=O)(OCC)OCC)OCC.COc1cc(COc2nn(-c3ccccc3)cc2C=O)ccc1OCc1cn(-c2ccccn2)nc1C>>CCOP(=O)(/C=C/c1cn(-c2ccccc2)nc1OCc1ccc(OCc2cn(-c3ccccn3)nc2C)c(OC)c1)OCC,,O,,CN(C)C=O,[H-].[Na+],test
US20130035325A1,N#CCC#N.O=C(CNc1cccc(CO)c1)c1ccc(Cl)cc1>>N#Cc1c(-c2ccc(Cl)cc2)cn(-c2cccc(CO)c2)c1N,,O,,CO,[K+].[OH-],test
US05378840,CCOC(=O)CCc1ccccn1.NN>>NNC(=O)CCc1ccccn1,,CCO,,O,,test
US05686482,COC(=O)c1ccc(OC(C)C)cc1O.COS(=O)(=O)OC>>COC(=O)c1ccc(OC(C)C)cc1OC,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150239921A1,CCOP(=O)(OCC)c1ccc2c(C(N)=O)nn(CC(=O)N3C[C@H](F)C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c1>>NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(P(=O)(O)O)ccc12,,ClCCl,,C[Si](C)(C)Br,,test
US20100179168A1,COc1ccc([N+](=O)[O-])cc1NC(C)=O>>COc1ccc(N)cc1NC(C)=O,[Pd],CCOC(C)=O,CO,,,test
US06011028,COC(=O)c1ccccc1C=CC1CCCCC(OC)=N1.[Cl-].[NH4+]>>COC(=O)c1ccccc1C=CC1CCCCC(=N)N1.Cl,,CO,,,,test
US20040029859A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C1CN(C(=O)OCc2ccccc2)CCN1>>O=C(OCc1ccccc1)N1CCNC(=S)C1,,C1CCOC1,,,,test
US05013738,COC(=O)c1ccc(C(=O)CCCOC(C)=O)cc1.C[P+](c1ccccc1)(c1ccccc1)c1ccccc1>>C=C(CCCOC(C)=O)c1ccc(C(=O)OC)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US06248765B1,CCC(C)(C)C(=O)O.OCCCc1c[nH]cn1.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>CCC(C)(C)NC(=O)OCCCc1c[nH]cn1,,CC#N,,CCN(CC)CC,Cl,test
US20150307463A1,NC(=O)c1cc(-c2ccc(CBr)cc2)no1.Oc1ccccc1Cl>>NC(=O)c1cc(-c2ccc(COc3ccccc3Cl)cc2)no1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20160115158A1,Cc1ncc(S(=O)(=O)Cl)cc1Cl.Nc1cncc(Cl)c1O>>Cc1ncc(S(=O)(=O)Nc2cncc(Cl)c2O)cc1Cl,,ClCCl,c1ccncc1,,,test
US20130345252A1,COc1ccc2c(c1)C(=O)c1c-2n(CCCBr)c(=O)c2cc([N+](=O)[O-])ccc12>>COc1ccc2c(c1)C(=O)c1c-2n(CCCBr)c(=O)c2cc(N)ccc12,,C1CCOC1,,CCOC(C)=O,CO,test
US20100227898A1,COC(c1sc2ccc(Cl)cc2c1Cl)C(C)[N+](=O)[O-]>>COC(c1sc2ccc(Cl)cc2c1Cl)C(C)N,,CCOCC,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20130085151A1,Cc1cc2cc([C@H](C)N3C(=O)c4ccccc4C3=O)c(-c3ccccn3)nc2s1>>Cc1cc2cc([C@H](C)N)c(-c3ccccn3)nc2s1,,CCO,CCOC(C)=O,NN,O,test
US20070197512A1,CCOC(=O)CCCN1C(=S)C(C(C)C)Oc2c(C(C)C)cccc21>>CC(C)c1cccc2c1OC(C(C)C)C(=S)N2CCCC(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20060079523A1,O=C(OO)c1cccc(Cl)c1.O=Cc1ccc(Sc2ccc(Cl)cc2)cc1>>O=Cc1ccc(S(=O)c2ccc(Cl)cc2)cc1,,ClCCl,,[K+].[OH-],,test
US20160016908A1,CC(=O)Cl.C[C@@H]1[C@@H](NC(=O)OCc2ccccc2)c2cc(F)ccc2N[C@H]1C>>CC(=O)N1c2ccc(F)cc2[C@H](NC(=O)OCc2ccccc2)[C@@H](C)[C@@H]1C,,ClCCl,,c1ccncc1,,test
US20050032850A1,CC(C)(Cc1ccc(F)cc1)NCC(O)COc1cccc2ccccc12.COc1ccc(CC(C)(C)NCC(O)COc2ccccc2)cc1.Cl>>COc1ccc(CC(C)(C)NCC(O)COc2ccc3ccccc3c2)cc1.Cl,,CCOCC,,Cl,Cl,test
US20150299183A1,COc1c(-n2cccn2)cccc1[N+](=O)[O-]>>COc1c(N)cccc1-n1cccn1,[Zn],CCO,,O,[Cl-].[NH4+],test
US20030119869A1,O=C(OCc1ccccc1)N1CCC(Nc2ccccc2[N+](=O)[O-])CC1>>Nc1ccccc1NC1CCN(C(=O)OCc2ccccc2)CC1,[Ni],C1CCOC1,,,,test
US20150005304A1,CC(C)O.Cc1cc(C(=O)N2CCC3(CC2)CC(O)C=C(c2cccnc2)O3)ccc1OC(C)C>>Cc1cc(C(=O)N2CCC3(CC2)CC(OC(C)C)C=C(c2cccnc2)O3)ccc1OC(C)C,,O,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US04857558,CC(C)(C)c1cc(SCCC=O)cc(C(C)(C)C)c1O.CC(C)[Mg]Cl>>CC(C)C(O)CCSc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1,,C1CCOC1,,Cl,O,test
US20110015180A1,Cc1ccc(Oc2cccc3[nH]c(C(=O)NC4CCN(CCN5CCCCCC5)CC4)cc23)cc1.NC1CCN(Cc2ccccc2)CC1>>Cc1ccc(Oc2cccc3[nH]c(C(=O)NC4CCN(Cc5ccccc5)CC4)cc23)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20070197626A1,CCOC(=O)Cc1ccc(OCC(=O)OC(C)(C)C)c(OCC)c1>>CCOC(=O)Cc1ccc(OCC(=O)O)c(OCC)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05319133,CCCC(CC)C(N)=O.OCl>>CCCC(C)C(=O)NCl,,CCOC(C)=O,,,,test
US20100331306A1,Nc1c(F)cccc1C(=O)O>>Nc1c(F)cccc1CO,,CCOCC,,C1CCOC1,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20060247238A1,CC(C)(C)OC(=O)N1C[C@H](NC(=O)c2ccc(Cl)s2)C[C@H]1COS(C)(=O)=O.CO>>COC[C@@H]1C[C@@H](NC(=O)c2ccc(Cl)s2)CN1C(=O)OC(C)(C)C,,C1CCOC1,,C[O-].[Na+],,test
US20160039794A1,C[C@H]1CNC[C@@H](C)N1.Nc1cc(Cl)ccc1[N+](=O)[O-]>>C[C@H]1CN(c2ccc([N+](=O)[O-])c(N)c2)C[C@@H](C)N1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20010006969A1,Cc1csc2c(Cl)nc(Cl)nc12.NCc1ccccc1>>Cc1csc2c(NCc3ccccc3)nc(Cl)nc12,,CN(C)C=O,,O,,test
US20110039820A1,N#CCc1cccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=O)C3)c1>>NCCc1cccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=O)C3)c1,[Ni],CO,O,,,test
US04609494,CCOC(=O)C1=C(C)NC(=O)N(C(C)=O)C1c1cc([N+](=O)[O-])ccc1OC(C)=O>>CCOC(=O)C1=C(C)NC(=O)N(C(C)=O)C1c1cc([N+](=O)[O-])ccc1O,,CCO,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20110015204A1,C[C@@H]1C[C@@H](O)c2ncnc(N3CCN(C(=O)[C@@H](c4ccc(Cl)cc4)[C@@H]4CCCN4C(=O)OC(C)(C)C)CC3)c21>>C[C@@H]1C[C@@H](O)c2ncnc(N3CCN(C(=O)[C@@H](c4ccc(Cl)cc4)[C@@H]4CCCN4)CC3)c21,,C1COCCO1,,Cl,,test
US20120157448A1,COC=C1CCC2(CC1Cc1ccc(Br)cc1)OCCO2>>O=CC1CCC(=O)CC1Cc1ccc(Br)cc1,,C1CCOC1,,,,test
US20150087585A1,COC(=O)c1cccc(-c2nc3ccc(N4CCC[C@@H](C(=O)N5CCCC5)C4)nc3[nH]2)n1.N>>NC(=O)c1cccc(-c2nc3ccc(N4CCC[C@@H](C(=O)N5CCCC5)C4)nc3[nH]2)n1,,C1COCCO1,Cc1ccccc1,C[Al](C)C,,test
US20080194535A1,COC(=O)[C@H](Cc1cc(Cl)cc(Cl)c1)NC(=O)OCc1ccccc1>>O=C(N[C@@H](Cc1cc(Cl)cc(Cl)c1)C(=O)O)OCc1ccccc1,,C1CCOC1,,[Li+].[OH-],,test
US20080221195A1,CC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C>>CC(O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C,,C1CCOC1,,[BH4-].[Li+],,test
US20070276000A1,COc1ccc2c(Oc3ccc(/C=C/C(=O)O)cc3)c(-c3ccccc3)c(C)cc2c1>>Cc1cc2cc(O)ccc2c(Oc2ccc(/C=C/C(=O)O)cc2)c1-c1ccccc1,,ClCCl,,BrB(Br)Br,O,test
US20120322791A1,CC(C)(C)[Si](C)(C)ON.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)(C)[Si](C)(C)ONC(=O)Oc1ccc([N+](=O)[O-])cc1,,CC(Cl)Cl,ClCCl,c1ccncc1,,test
US20030109687A1,CC(C)N=C(NC(C)C)OCc1ccccc1.O=C(O)c1ccc(O)cc1>>O=C(OCc1ccccc1)c1ccc(O)cc1,,C1CCOC1,,,,test
US20110201604A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.FCCNCCN(Cc1ccccc1)Cc1ccccc1>>CC(C)(C)OC(=O)N(CCF)CCN(Cc1ccccc1)Cc1ccccc1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US07071201B2,Cl.OCc1ccc2c(c1)N(C1CCN(CCc3ccc(F)cc3)CC1)CC2>>Fc1ccc(CCN2CCC(N3CCc4ccc(CCl)cc43)CC2)cc1,,CCOC(C)=O,,[Na+].[OH-],,test
US06759547B1,CCOC(=O)/C(F)=C(C)/C=C/C(F)=C(/CC)c1cc2c(cc1OCC)C(C)(C)CCC2(C)C>>CCOc1cc2c(cc1/C(CC)=C(F)\C=C\C(C)=C(/F)C(=O)O)C(C)(C)CCC2(C)C,,CCO,,[Na+].[OH-],,test
US20100210632A1,C#Cc1ccc(N2C(=O)c3[nH]nc(C(C)(C)C)c3C2c2ccccc2OC)cc1.CCOC(=O)C(Cl)=NO>>CCOC(=O)c1cc(-c2ccc(N3C(=O)c4[nH]nc(C(C)(C)C)c4C3c3ccccc3OC)cc2)on1,,C1CCOC1,,CCN(CC)CC,,test
US06413974B1,Clc1nc(Cl)c2ncn(C3CCCC3)c2n1.NCCc1ccc2c(c1)OCO2>>Clc1nc(NCCc2ccc3c(c2)OCO3)c2ncn(C3CCCC3)c2n1,,CCN(CC)CC,,,,test
US20150218172A1,C#CC1CC1.CCOC(=O)CN=[N+]=[N-]>>CCOC(=O)Cn1cc(C2CC2)nn1,I[Cu]I,CC#N,,CCN(CC)CC,,test
US20100249071A1,CCOC(=O)c1cn2ccsc2n1.NN>>NNC(=O)c1cn2ccsc2n1,,CCO,,O,,test
US20090203633A1,CC(=O)OC[C@H]1O[C@@H](Oc2n[nH]c(C(C)C)c2Cc2ccc(OCCCO)cc2C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.CC(C)(NS(=O)(=O)c1ccccc1[N+](=O)[O-])C(N)=O>>CC(=O)OC[C@H]1O[C@@H](Oc2n[nH]c(C(C)C)c2Cc2ccc(OCCCN(C(C)(C)C(N)=O)S(=O)(=O)c3ccccc3[N+](=O)[O-])cc2C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090131481A1,NCc1ccc(N)cc1.O=[N+]([O-])c1ccc(F)c([N+](=O)[O-])c1>>Nc1ccc(CNc2ccc([N+](=O)[O-])cc2[N+](=O)[O-])cc1,,CN(C)C=O,O,O=C([O-])O.[Na+],,test
US20050192294A1,COc1cccc(C)c1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1cccc(C)c1OS(=O)(=O)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20070010511A1,COC(=O)c1cccc(N)c1N.COCCCC(=O)O>>COCCCc1nc2cccc(C(=O)OC)c2[nH]1,,Cl,,,,test
US04933336,CC1SC(=O)NN=C1c1ccc2c(c1)C(C)(C)C(=O)N2.O=C=NC(=O)C(Cl)(Cl)Cl>>CC1SC(=O)NN=C1c1ccc2c(c1)C(C)(C)C(=O)N2C(N)=O,,CN(C)C=O,ClCCl,[H-].[Na+],,test
US20030109459A1,CI.COCCC1(C(=O)N[C@@H](Cc2ccc([N+](=O)[O-])cc2)C(=O)OC)CCCC1>>COCCC1(C(=O)N(C)[C@@H](Cc2ccc([N+](=O)[O-])cc2)C(=O)OC)CCCC1,O=[Ag],CN(C)C=O,,,,test
US20150119385A1,N#Cc1cnc(N)cc1F.OC1CN2CCC1CC2>>N#Cc1cnc(N)cc1OC1CN2CCC1CC2,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20120157448A1,CI.OCC1CCC=CO1>>COCC1CCC=CO1,,CN(C)C=O,,[H][H],[H-].[Na+],test
US20150361091A1,CO[C@@H]1CCN(c2ccc3c(c2)OC[C@H]2[C@H](CO[Si](C)(C)C(C)(C)C)OC(=O)N32)C(=O)C1>>CO[C@@H]1CCN(c2ccc3c(c2)OC[C@H]2[C@H](CO)OC(=O)N32)C(=O)C1,,ClCCl,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040122057A1,CCOC(C(=O)O)c1ccc(OC)c(OCc2ccccc2)c1>>CCOC(C(=O)O)c1ccc(OC)c(O)c1,[Pd],CCO,,,,test
US20130005710A1,COc1ccc(N2CCN(c3ccc(OC)nc3-c3ccc(C(C)=O)cc3)CC2)cc1.C[Mg]Br>>COc1ccc(N2CCN(c3ccc(OC)nc3-c3ccc(C(C)(C)O)cc3)CC2)cc1,,O,,C1CCOC1,,test
US20090227583A1,O=[N+]([O-])c1ccc2nc(NC3CCc4cc(F)ccc43)ccc2c1>>Nc1ccc2nc(NC3CCc4cc(F)ccc43)ccc2c1,[Pd],CCOC(C)=O,,,,test
US20150126485A1,O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(F)c(-c2cncs2)c1.O[C@@H]1CCNC1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(N2CC[C@@H](O)C2)c(-c2cncs2)c1,,CS(C)=O,,,,test
US20100173933A1,N=C(NO)c1ccc2c(c1)OCO2.O=C(Br)CBr>>BrCc1nc(-c2ccc3c(c2)OCO3)no1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20150045374A1,BrBr.Cc1ccc2cc(O)c(C)cc2n1>>Br.Cc1ccc2c(Br)c(O)c(C)cc2n1,,CC(=O)O,,,,test
US06063761,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCCCCC(=O)O>>CC(C)(C)OC(=O)C(CCCCN)C(=O)O,,C1COCCO1,O,,,test
US05585395,O=[N+]([O-])c1ccc2c(c1)OC(C(Cl)C(F)(F)F)(C(F)(F)F)O2>>Nc1ccc2c(c1)OC(C(Cl)C(F)(F)F)(C(F)(F)F)O2,[Pd],C1CCOC1,,[H][H],,test
US20080242596A1,CCc1ccc(Cc2cc([C@@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)c(CCOCC=O)cc2Cl)cc1>>CCc1ccc(Cc2cc([C@@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)c(CCOCCO)cc2Cl)cc1,,C1CCOC1,,CO,[BH4-].[Na+],test
US20070197478A1,O=[N+]([O-])c1c(NCc2ccccc2)cc(C2CC2)nc1Cl>>Nc1c(NCc2ccccc2)cc(C2CC2)nc1Cl,[Fe],CC(=O)O,,O,,test
US05516774,COC(=O)CBr.N#Cc1ccccc1N>>COC(=O)CNc1ccccc1C#N,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05128069,CC(=O)c1ccc(O)cc1.Cc1ccc(S(=O)(=O)OCCNC(=O)OCc2ccccc2)cc1>>CC(=O)c1ccc(OCCNC(=O)OCc2ccccc2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06486316B1,Clc1ccccc1Cl.Clc1nc(Cl)nc(Cl)n1.c1ccccc1>>Clc1nc(-c2ccccc2)nc(-c2ccccc2)n1,,Clc1ccccc1Cl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20030229094A1,O=C(CCl)Nc1ccc(F)cc1F.c1ccc(N2CCNCC2)nc1>>O=C(CN1CCN(c2ccccn2)CC1)Nc1ccc(F)cc1F,,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20060074084A1,CCOC(=O)c1[nH]c2ccc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)cc2c1Br.COc1cccc(B(O)O)c1>>CCOC(=O)c1[nH]c2ccc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)cc2c1-c1cccc(OC)c1,,CCCCCC,CCOC(C)=O,,,test
US20090215728A1,CSc1ccc(N2C(=O)NC(C)(C)C2=O)cc1C(F)(F)F.O>>CS(=O)c1ccc(N2C(=O)NC(C)(C)C2=O)cc1C(F)(F)F,,C1CCOC1,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20060160794A1,CNCc1ccccc1Cl.O=C(O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-c1ccccn1>>CN(Cc1ccccc1Cl)C(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-c1ccccn1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20160145247A1,CC(C)(C)OC(=O)N[C@H](CO)c1cccc(Br)c1.CCOC(C)=O>>CCOC[C@@H](NC(=O)OC(C)(C)C)c1cccc(Br)c1,,O,,CN(C)C=O,[H-].[Na+],test
US20100311749A1,CC(C)(C)OC(=O)N1CCN(c2cc(N3CCOCC3)ccc2Cl)C(=O)C1>>O=C1CNCCN1c1cc(N2CCOCC2)ccc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100041667A1,CCOC(=O)C1(C(=O)OCC)C(c2ccccc2)CCN1C(C)=O>>CC(=O)N1CCC(c2ccccc2)[C@H]1C(=O)O,,CCO,,[K+].[OH-],,test
US20160175284A1,CB1OB(C)OB(C)O1.CC1=C(c2ccc(F)cc2)C(c2ccc(OCCN3CC(CF)C3)cc2)Oc2cc(Br)c(OC3CCCCO3)cc21>>CC1=C(c2ccc(F)cc2)C(c2ccc(OCCN3CC(CF)C3)cc2)Oc2cc(C)c(OC3CCCCO3)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160108056A1,Cn1c(C(=O)Nc2cccc(-c3ccc(F)cc3F)c2)cc2ccc([N+](=O)[O-])cc21>>Cn1c(C(=O)Nc2cccc(-c3ccc(F)cc3F)c2)cc2ccc(N)cc21,[Zn],CO,O,[Cl-].[NH4+],,test
US20080293712A1,CCOC(=O)CC#N.COc1cc(N)c(C(C)=O)cc1OC>>COc1cc2[nH]c(=O)c(C#N)c(C)c2cc1OC,,O,,C,O=C[O-].[NH4+],test
US20090182142A1,Nc1ccc(-c2cc(NCc3ccc(Cl)cc3Cl)n3nccc3n2)cc1.O=S(=O)(Cl)CCCCl>>O=S(=O)(CCCCl)Nc1ccc(-c2cc(NCc3ccc(Cl)cc3Cl)n3nccc3n2)cc1,,C1CCOC1,,CCOC(C)=O,,test
US20060106020A1,COc1nncc2c1c1cc(F)ccc1c1nc(C(C)(C)C)n(O)c21>>CC(C)(C)c1nc2c3ccc(F)cc3c3c(O)nncc3c2n1O,,CCO,Cl,,,test
US20110263548A1,COC(=O)CC(=O)CC(=O)OC.CS(=O)(=O)c1ccc([N+]#N)cc1>>COC(=O)CC(=O)/C(=N\Nc1ccc(S(C)(=O)=O)cc1)C(=O)OC,,CCO,O,CC(=O)[O-].[Na+],,test
US20110053916A1,C#Cc1cnc(-c2ccc(CO[Si](C)(C)C(C)(C)C)s2)nc1Nc1cc(C2CC2)n[nH]1>>C#Cc1cnc(-c2ccc(CO)s2)nc1Nc1cc(C2CC2)[nH]n1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06861425B2,CC1(N2CCC(n3c(Cl)nc4ccccc43)CC2)CCCCCCC1.CN1C2CCC1CC(O)C2>>CN1C2CCC1CC(Oc1nc3ccccc3n1C1CCN(C3(C)CCCCCCC3)CC1)C2,,CN(C)C=O,,[H-].[Na+],,test
US20140249154A1,CN.Cl.O=C(O)c1sc(Nc2ncccn2)nc1-c1ccccn1>>CNC(=O)c1sc(Nc2ncccn2)nc1-c1ccccn1.Cl,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20160002214A1,COc1ccc(C(=O)O)cc1.N/C(=N\O)c1ccc(-c2nc3cc(C(F)(F)F)ccc3[nH]2)cc1>>COc1ccc(-c2nc(-c3ccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)cc3)no2)cc1,,CN(C)C=O,,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US07319104B2,CC(N)=O.O=C(COC(=O)C1CC1)c1ccc(Br)cc1>>Brc1ccc(-c2coc(C3CC3)n2)cc1,,O,,CCOCC,FB(F)F,test
US20050119295A1,CC(C)(C)OC(=O)N1CCc2nn(-c3ccccc3)c(OS(=O)(=O)C(F)(F)F)c2CC1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>c1ccc(-c2c3c(nn2-c2ccccc2)CCNCC3)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160096834A1,O=C(Cl)C1CC1.[H]/N=C(\NO)C(=O)OCC>>CCOC(=O)c1noc(C2CC2)n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110319420A1,CC(C)(C)OC(=O)N1CCNCC1.ClC1CCc2cc(Br)ccc21>>CC(C)(C)OC(=O)N1CCN(C2CCc3cc(Br)ccc32)CC1,,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20120322785A1,Cc1ccc(F)cc1-c1cc2cnc(NC(=O)C3CC3)cc2c(C)[n+]1[O-]>>Cc1ccc(F)cc1-c1cc2cnc(NC(=O)C3CC3)cc2c(CO)n1,,ClCCl,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US20040157836A1,CC(C)(C)OC(=O)N1CCC(CNc2ccccc2S(=O)(=O)Nc2ccc3c(c2C(=O)O)CCCC3)CC1.CO>>COC(=O)c1c(NS(=O)(=O)c2ccccc2NCC2CCN(C(=O)OC(C)(C)C)CC2)ccc2c1CCCC2,,CO,c1ccccc1,C[Si](C)(C)C=[N+]=[N-],,test
US20080269196A1,CC(C)(C)C(=O)Cl.N#Cc1ccc(CN)cc1>>CC(C)(C)C(=O)NCc1ccc(C#N)cc1,,ClCCl,,CCN(CC)CC,,test
US20060052597A1,Cl.O=C(O)c1ccc(OCCCN2CCCCC2)cc1.O=S(Cl)Cl>>Cl.O=C(Cl)c1ccc(OCCCN2CCCCC2)cc1,,O=S(Cl)Cl,,,,test
US20020119983A1,COc1ccccc1N1CCNCC1.O=CCCc1cc(-c2ccc(Cl)cc2)no1>>COc1ccccc1N1CCN(CCCc2cc(-c3ccc(Cl)cc3)no2)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130029973A1,CNCC(O)CO.COC(=O)c1ccc(CCc2ccc(NC(=O)c3c(NC(=O)c4cccc(S(=O)(=O)Cl)c4)sc4c3CCCC4)cc2)cc1>>COC(=O)c1ccc(CCc2ccc(NC(=O)c3c(NC(=O)c4cccc(S(=O)(=O)N(C)CC(O)CO)c4)sc4c3CCCC4)cc2)cc1,,ClCCl,,,,test
US20030055064A1,CCCCCC.C[Mg]Br.O=C(Cl)c1ccc(CCl)cc1>>CC(C)(O)c1ccc(CCl)cc1,,C1CCOC1,CCCCCC,CCOC(C)=O,[Cl-].[NH4+],test
US20130102596A1,CNC(=O)COc1cccc(Nc2ncc(F)c(Nc3ccc4c(c3)NC(=O)C(F)(F)O4)n2)c1.O=C(O)c1ccc2ccccc2c1O>>CNC(=O)COc1cccc(Nc2ncc(F)c(Nc3ccc4c(c3)NC(=O)C(F)(F)O4)n2)c1.O=C(O)c1ccc2ccccc2c1O,,CCC(C)=O,,O,,test
US20140303127A1,CN(CCN)[C@@H]1CC[C@@H](OC(=O)C(O)(c2cccs2)c2cccs2)CC1.O=C(O)COc1ccc(CO)cc1>>CN(CCNC(=O)COc1ccc(CO)cc1)[C@@H]1CC[C@@H](OC(=O)C(O)(c2cccs2)c2cccs2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100152207A1,Cc1cccc(O)c1N(C)C(=O)c1ccc(Cl)c(Br)c1.OCCCBr>>Cc1cccc(OCCCO)c1N(C)C(=O)c1ccc(Cl)c(Br)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20050176775A1,Cc1cc(O)c(Cl)c(=O)[nH]1.Fc1ccc(CBr)c(F)c1>>Cc1cc(OCc2ccc(F)cc2F)c(Cl)c(=O)[nH]1,,CN1CCCC1=O,,C1CCC2=NCCCN2CC1,,test
US20020198197A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOc1cc(N)c([N+](=O)[O-])cc1C(F)(F)F>>CCOc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100317673A1,O=C(Nc1ccccn1)c1cn2cc(Br)ccc2n1.OCc1cccc(B(O)O)c1>>O=C(Nc1ccccn1)c1cn2cc(-c3cccc(CO)c3)ccc2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US05780480,CC(C)(C)OC(=O)N1CCC(CCCI)CC1.O=Cc1ccc(O)cc1>>CC(C)(C)OC(=O)N1CCC(CCCOc2ccc(C=O)cc2)CC1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20120053053A1,C=Cc1c(N)nc(-c2ccc(Cl)c(N(C)C)c2F)nc1C(=O)OC.CCO>>C=Cc1c(N)nc(-c2ccc(Cl)c(N(C)C)c2F)nc1C(=O)OCC,,Cc1ccccc1,,,,test
US20160152605A1,COC(=O)c1ccc([C@@H]2C[C@H](C)CCN2)cc1.COc1cc(C)c2c(ccn2C(=O)OC(C)(C)C)c1C=O>>COC(=O)c1ccc([C@@H]2C[C@H](C)CCN2Cc2c(OC)cc(C)c3c2ccn3C(=O)OC(C)(C)C)cc1,,CCOC(C)=O,ClCCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090170916A1,CCOC(=O)C(=O)CC(=O)CCC1C(C)CCCC1(C)C.NN>>CCOC(=O)c1cc(CCC2C(C)CCCC2(C)C)[nH]n1,,CCO,,O,,test
US20030100576A1,C1COCCN1.CC(=O)OCCBr>>CCOC(=O)CN1CCOCC1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US04080505,CC(=O)OC(C)=O.CC(C)(COc1ccc(CC(Cl)C(N)=O)cc1)c1ccccc1>>CC(=O)NC(=O)C(Cl)Cc1ccc(OCC(C)(C)c2ccccc2)cc1,O=S(=O)(O)O,Cc1ccccc1,,,,test
US20090075938A1,C1COCCN1.O=[N+]([O-])c1ccc2oc(=S)[nH]c2c1>>O=[N+]([O-])c1ccc2oc(N3CCOCC3)nc2c1,,C1CCOC1,,O,,test
US04557756,CN(C)C(=O)CC(C)(C)CC(=O)O.CN(C)C(=O)Nc1cccc(N)c1>>CN(C)C(=O)CC(C)(C)CC(=O)Nc1cccc(NC(=O)N(C)C)c1,,C1CCOC1,,CCN(CC)CC,CS(=O)(=O)Cl,test
US04431808,COc1ccc(Br)c(C=O)c1.Fc1ccc(F)c(S)c1>>COc1ccc(Sc2cc(F)ccc2F)c(C=O)c1,[Cu],O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20160120841A1,COc1ccc(C(=O)/C=C/c2cccnc2)c(O)c1>>COc1ccc2c(c1)OC(c1cccnc1)CC2=O,,CCO,,Cl,O,test
US20070105904A1,Brc1ccc(C2OCCO2)cn1.CN(C)C=O>>O=Cc1ccc(C2OCCO2)cn1,,O,,C1CCOC1,[Li]CCCC,test
US20040067998A1,Brc1ccc2[nH]ccc2c1.Fc1ccc(CCl)cc1>>Fc1ccc(Cn2ccc3cc(Br)ccc32)cc1,,CN(C)C=O,,[H][H],[H-].[Na+],test
US04843082,C=CC(C)=O.Nc1ccccc1O>>Cc1ccnc2c(O)cccc12,,Cl,,[Na+].[OH-],,test
US20150291629A1,CNC.O=Cc1ccc(Oc2ccc3c(c2)COB3O)cc1>>CNCc1ccc(Oc2ccc3c(c2)COB3O)cc1,,CO,,Cl,[BH4-].[Na+],test
US04665057,CCCCCC(=O)Cl.c1c[nH]cn1>>CCCCCC(=O)n1ccnc1,,Cc1ccccc1,,,,test
US20020049201A1,CCC(CC)ONC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12.O=[N+]([O-])c1cccc(S(=O)(=O)Cl)c1>>CCC(CC)ON(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@@H]12)S(=O)(=O)c1cccc([N+](=O)[O-])c1,CN(C)c1ccccn1,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US05093525,CCc1cccc(NC#N)c1.Nc1cccc2ccccc12>>CCc1cccc(NC(=N)Nc2cccc3ccccc23)c1,,Clc1ccccc1,,Cl,,test
US20160052898A1,COC(=O)c1ccc(OCc2ccccc2)c(N)c1.O=C(Cl)CCl>>COC(=O)c1ccc(OCc2ccccc2)c(NC(=O)CCl)c1,,ClCCl,,c1ccncc1,,test
US04962109,Fc1c(F)c(CC2CC2(Cl)Cl)c(F)c(F)c1COC1CCCCO1>>OCc1c(F)c(F)c(CC2CC2(Cl)Cl)c(F)c1F,,CO,Cl,,,test
US04111942,CCCCCC(C)C(C)c1cc(N)c2c(c1)OC(C)(C)c1ccncc1-2.Cl.O=C(O)CCCN1CCCCC1>>CCCCCC(C)C(C)c1cc(NC(=O)CCCN2CCCCC2)c2c(c1)OC(C)(C)c1ccncc1-2.Cl,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20080009509A1,CC(C)(C)OC(=O)NCCCC(=O)Nc1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1>>NCCCC(=O)Nc1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20080280875A1,CCOC(=O)CCC(=O)OCC.Cc1cc(C=O)co1>>CCOC(=O)C(=Cc1coc(C)c1)CC(=O)O,,CCO,,C,C[O-].[Na+],test
US06362201B1,CC(=O)OCc1c2ccccc2c(COC(C)=O)c2ccccc12.NCCCn1ccc2cccc(C(=O)N3C[C@@H](C4CC4)[C@H](CN4CCC(c5ccc(F)cc5)CC4)C3)c21>>CC(=O)NCCCn1ccc2cccc(C(=O)N3C[C@@H](C4CC4)[C@H](CN4CCC(c5ccc(F)cc5)CC4)C3)c21,,ClCCl,,CCN(CC)CC,,test
US20140296272A1,CCCC(C(=O)OC)c1c(C)nc2sc3c(c2c1-c1ccco1)CCC3>>CCCC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1ccco1)CCC3,,CO,,Cl,[Na+].[OH-],test
US20160271130A1,COc1ccc(S(=O)(=O)Cl)cc1.Cc1ccc(Nc2cc(C(C)C)nc(N3CCNCC3)n2)cc1>>COc1ccc(S(=O)(=O)N2CCN(c3nc(Nc4ccc(C)cc4)cc(C(C)C)n3)CC2)cc1,,ClCCl,,c1ccncc1,,test
US20110034450A1,O=C(O)/C=C/c1ccc(NC(=O)C(c2ccc(CN3N=C(c4ccccc4)OCC3=O)cc2)C2CCCC2)cc1>>O=C(O)CCc1ccc(NC(=O)C(c2ccc(CN3N=C(c4ccccc4)OCC3=O)cc2)C2CCCC2)cc1,[Pd],CCO,,,,test
US20150175604A1,C=O.Cc1cc2c(cc(NC3CCNCC3)c3nnc(C)n32)n1Cc1ccccc1>>Cc1cc2c(cc(NC3CCN(C)CC3)c3nnc(C)n32)n1Cc1ccccc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20120309738A1,CNc1cc(N2CCCC(C(F)(F)F)C2)c(Cl)cc1[N+](=O)[O-]>>CNc1cc(N2CCCC(C(F)(F)F)C2)c(Cl)cc1N,[Pt],CO,,C1CCOC1,,test
US20130317218A1,Cc1ccc(C(=O)Cl)cc1[N+](=O)[O-].NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1N>>Cc1ccc(C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)cc1[N+](=O)[O-],,c1ccncc1,,,,test
US20060052392A1,CS(=O)(=O)Cl.Cc1cc2c(cc1C)C(CCO)N(c1cccnc1)C2=O>>Cc1cc2c(cc1C)C(CCOS(C)(=O)=O)N(c1cccnc1)C2=O,,ClCCl,,CCN(CC)CC,,test
US20110046370A1,CC(=O)OC(C)=O.CNc1cc(-n2cc(-c3cccc(N)c3)c3ccc(-c4ccc(OC)cc4)cc32)ncn1>>CNc1cc(-n2cc(-c3cccc(NC(C)=O)c3)c3ccc(-c4ccc(OC)cc4)cc32)ncn1,,ClCCl,,c1ccncc1,O=C([O-])O.[Na+],test
US20090005410A1,CCOC(=O)c1cn(-c2cc(Cl)ccc2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nn1.N>>CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-n2cc(C(N)=O)nn2)cc1,,CCO,,,,test
US05665754,CCC(=O)OC(=O)CC.COC(=O)[C@@H]1CNC[C@H]1c1ccc(OC)c(OC2CCCC2)c1>>CCC(=O)N1C[C@@H](C(=O)OC)[C@H](c2ccc(OC)c(OC3CCCC3)c2)C1,CN(C)c1ccncc1,ClCCl,,,,test
US20100022550A1,Cl.O=S(Cl)Cl.OCc1ccc(F)cn1>>Cl.Fc1ccc(CCl)nc1,,ClCCl,,O=C([O-])O.[Na+],,test
US20100137397A1,CCOCCC(C(=O)OC)(C(=O)OC)[C@@H]1c2ccccc2C[C@H]1NC(=O)OC(C)(C)C.Cl>>CCOCCC(C(=O)OC)(C(=O)OC)[C@@H]1c2ccccc2C[C@H]1N.Cl,,CO,ClCCl,,,test
US20060111357A1,CCOC(C)=O.Oc1ccccc1OC(F)(F)F>>CCOC(=O)COc1ccc(OC(F)(F)F)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120142717A1,CCc1c[nH]c(OCCc2cc(F)c(Oc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)nc1=O.CI>>CCc1cn(C)c(OCCc2cc(F)c(Oc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)nc1=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160046613A1,BrCc1ccccc1.COCOc1cc(O)ccc1Cl>>COCOc1cc(OCc2ccccc2)ccc1Cl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04116956,CCOC(C)([O-])[O-].COc1ccc(C2=NCC(NN)=Nc3ccc(Cl)cc32)cc1>>COc1ccc(C2=NCc3nnc(C)n3-c3ccc(Cl)cc32)cc1,,CCO,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US20050197350A1,C[Al](C)C.Cc1cnc(Cl)nc1Cl>>Cc1cnc(Cl)nc1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,,,test
US20100063081A1,C[Si](C)(C)C=[N+]=[N-].O=C(O)c1ccc(O)cc1F>>COC(=O)c1ccc(O)cc1F,,CCCCCC,Cc1ccccc1,CC(=O)O,O,test
US20060100262A1,CN(C)CC(=O)O.COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CCNCc1cc(F)ccc1-3>>COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CCN(C(=O)CN(C)C)Cc1cc(F)ccc1-3,,Cl,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090118327A1,CNC.CSC1=NCC(c2ccc([N+](=O)[O-])cc2)c2cc(Cl)ccc21>>CN(C)C1=NCC(c2ccc([N+](=O)[O-])cc2)c2cc(Cl)ccc21,,C1CCOC1,,,,test
US20070265226A1,COCCl.N#Cc1ccc(Br)c(CO)c1>>COCOCc1cc(C#N)ccc1Br,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US04604389,CNCCCOc1cc(Br)c(N)c(Br)c1.COc1cc2c(cc1OC)CC(=O)N(CCCCl)CC2>>COc1cc2c(cc1OC)CC(=O)N(CCCN(C)CCCOc1cc(Br)c(N)c(Br)c1)CC2,,CCN(CC)CC,,,,test
US20050113388A1,NCCCCc1ccc(C(=O)O)cc1.O=C(Cl)OCc1ccccc1>>O=C(NCCCCc1ccc(C(=O)O)cc1)OCc1ccccc1,,C1CCOC1,,O,O=C([O-])O.[Na+],test
US04045567,CCC(N)=S.CCOC(=O)C(Cl)C=O>>CCc1ncc(C(=O)O)s1,,CCO,,,,test
US20080312232A1,COC(=O)c1c(C)n(C)n(-c2ccccc2)c1=O.O=C1CCC(=O)N1Br>>COC(=O)c1c(CBr)n(C)n(-c2ccccc2)c1=O,,ClC(Cl)Cl,,,,test
US04727082,ClC/C=C/CCl.O=Cc1cc([N+](=O)[O-])ccc1O>>O=Cc1cc([N+](=O)[O-])ccc1OC/C=C/CCl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110129455A1,Cn1ncc(Cl)c1-n1cnc(C(=O)O)c1.N[C@@H](Cc1ccc(F)c(F)c1)CN1C(=O)c2ccccc2C1=O>>Cn1ncc(Cl)c1-n1cnc(C(=O)N[C@@H](Cc2ccc(F)c(F)c2)CN2C(=O)c3ccccc3C2=O)c1,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20100331326A1,CON=Cc1ccc(N2CCN(c3cnccc3C)C2=O)cc1F.NN>>Cc1ccncc1N1CCN(c2ccc3cn[nH]c3c2)C1=O,,ClC(Cl)Cl,,CO,O,test
US06432993B1,CCN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(O)c(C(C)(C)C)c2)ccc1[N+](=O)[O-]>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(O)c(C(C)(C)C)c2)ccc1N,[Pd],CO,,,,test
US20110212918A1,O=[N+]([O-])c1cnc(Cl)c(C(F)(F)F)c1.SCc1ccccc1>>O=[N+]([O-])c1cnc(SCc2ccccc2)c(C(F)(F)F)c1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20050026921A1,CC#CCN1C(C(=O)OC)=C(C(=O)OC)NC1Br>>CC#CCn1c(Br)nc(C=O)c1C(=O)OC,,C1CCOC1,,CC(C)C[Al+]CC(C)C.[H-],,test
US06936602B1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3Cc2csc(C)n2)cc1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3Cc2csc(C)n2)cc1,,C1CCOC1,CO,Cl,O,test
US20070049581A1,COCCOCCO.Nc1c(Cl)cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCN(C3CCN(CC(=O)O)CC3)CC2)cc1C(F)(F)F>>COCCOCCOC(=O)CN1CCC(N2CCN(C(=O)[C@@H](Cc3cc(Cl)c(N)c(C(F)(F)F)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20090182023A1,CC(=O)NCCC1CCc2ccc(N)c(O)c21.O=C(Cl)CCc1ccccc1>>CC(=O)NCCC1CCc2ccc(NC(=O)CCc3ccccc3)c(O)c21,,c1ccncc1,,Cl,O,test
US20160229843A1,ClC(Cl)(Cl)c1nc2ccccc2[nH]1.Nc1ccc(Br)cc1O>>Brc1ccc2nc(-c3nc4ccccc4[nH]3)oc2c1,,CCO,,CCN(CC)CC,,test
US05025031,CNS(=O)(=O)Cl.Oc1ccccc1>>CNS(=O)(=O)Oc1ccccc1,,Cc1ccccc1,,,,test
US20110294776A1,N#Cc1ccc(C2CN(C(=O)OCc3ccccc3)C2)n1N.N=CN>>Nc1ncnn2c(C3CN(C(=O)OCc4ccccc4)C3)ccc12,,CCCCO,,CC(=O)O,,test
US20130289067A1,CCOC1CC2=C(CCCC2=O)O1>>CCOC1CC2C(=O)CCCC2O1,[Pd],CCOC(C)=O,,,,test
US20100152192A1,COc1cccc(/C=C/c2nc3sccn3c2C(=O)O)c1OCC(C)(C)C.Nc1nc(C(F)(F)F)cs1>>COc1cccc(/C=C/c2nc3sccn3c2C(=O)Nc2nc(C(F)(F)F)cs2)c1OCC(C)(C)C,CN(C)c1ccncc1,CN(C)C=O,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US20130045962A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)N(C(=O)OC(C)(C)C)c1nc(Cl)nc(Cl)c1F.CNCc1csc(N)n1>>CN(Cc1csc(N)n1)c1nc(Cl)nc(N(C(=O)OC(C)(C)C)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1F,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20090286782A1,COc1ccc(CN(C(=O)OC(C)(C)C)c2ccc(C(=O)c3c[nH]c4ncncc34)cn2)cn1>>COc1ccc(CNc2ccc(C(=O)c3c[nH]c4ncncc34)cn2)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080275037A1,CC(C)(C)[Si](C)(C)Cl.COc1ncc([C@@H](O)CO)cn1>>COc1ncc([C@@H](O)CO[Si](C)(C)C(C)(C)C)cn1,,ClCCl,,O,c1c[nH]cn1,test
US20080182874A1,C=CC(=O)OC.O=C(NCCC12CC3CC(CC(C3)C1)C2)c1c(Cl)ccc2nc(N3CCNCC3)ccc12>>COC(=O)CCN1CCN(c2ccc3c(C(=O)NCCC45CC6CC(CC(C6)C4)C5)c(Cl)ccc3n2)CC1,,CCN(CC)CC,ClCCl,O=C([O-])O.[Na+],,test
US20040077638A1,COC(=O)CC1c2ccccc2C(=O)N(C)c2cc(OCCCCNc3ccccn3)ccc21>>CN1C(=O)c2ccccc2C(CC(=O)O)c2ccc(OCCCCNc3ccccn3)cc21,,O,,CO,[Na+].[OH-],test
US20060111426A1,COC(=O)Cn1c(C)c(S(=O)(=O)c2ccc(Cl)cc2)c2cc(Cl)ccc21>>Cc1c(S(=O)(=O)c2ccc(Cl)cc2)c2cc(Cl)ccc2n1CC(=O)O,,C1CCOC1,,[Na+].[OH-],,test
US20110144090A1,CCn1cc(CC(=O)N(C)C)c2c(OC)c(CCC(N)=O)cc(F)c21>>CCn1cc(CCN(C)C)c2c(OC)c(CCCN)cc(F)c21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04217357,CC(C)c1[nH]c2ccccc2c1CN(C)C.c1c[nH]cn1>>CC(C)c1[nH]c2ccccc2c1Cn1ccnc1,,Cc1ccccc1C,,,,test
US20150252030A1,COC(=O)COc1c(C)cc(C)cc1C.NN>>Cc1cc(C)c(OCC(=O)NN)c(C)c1,,C1CCOC1,,O,,test
US20030087920A1,COC(=O)C(Oc1ccccc1OC)C(=O)OC.N=CN>>COc1ccccc1Oc1c(O)ncnc1O,,CO,,Cl,C[O-].[Na+],test
US05919780,NCCc1cccnc1.S=C1Nc2cc(Cl)ccc2Nc2ccccc21>>Clc1ccc2c(c1)N=C(NCCc1cccnc1)c1ccccc1N2,,CCOCCO,,,,test
US06235355B1,CCCC(CO)CO.Cc1ccccc1.O=CC1CCC(c2ccc(OC(F)(F)F)c(F)c2)CC1>>Fc1cc(C2CCC(C3OCCCO3)CC2)ccc1OC(F)(F)F,,Cc1ccccc1,,,,test
US20120214769A1,CC(C)(C)c1ccc(C(Cc2ccc(N)cc2)C(=O)Nc2ccccc2-c2ccc3cccc-3o2)cc1.O=C1CCC(=O)O1>>CC(C)(C)c1ccc(C(Cc2ccc(NC(=O)CCC(=O)O)cc2)C(=O)N(c2ccccc2)c2ccc3cccc-3o2)cc1,,CCOCC,Cc1ccccc1,C1COCCO1,,test
US20110263648A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCCC1(O)CC2CCC1c1ccccc12>>Cc1ccc(S(=O)(=O)OCC[C@]2(O)C[C@H]3CC[C@@H]2c2ccccc23)cc1,CN(C)c1ccncc1,Cc1ccccc1,,CCN(CC)CC,,test
US20160009720A1,C=CB1OC(C)(C)C(C)(C)O1.Cc1ccc(S(=O)(=O)Oc2nc(-c3ccc(C#N)cc3)c(-c3ccc(N4CCCC4=O)nc3)n3ccnc23)cc1>>C=Cc1nc(-c2ccc(C#N)cc2)c(-c2ccc(N3CCCC3=O)nc2)n2ccnc12,,O,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20120128630A1,CC(C)c1ccc(C(=O)C2=C(O)C(=O)N(c3ccc(Cl)nn3)C2c2ccc(OC(F)(F)F)cc2)cc1.O=[N+]([O-])c1ccc(S)cc1>>CC(C)c1ccc(C(=O)C2=C(O)C(=O)N(c3ccc(Sc4ccc([N+](=O)[O-])cc4)nn3)C2c2ccc(OC(F)(F)F)cc2)cc1,,O,c1ccncc1,,,test
US20040180934A1,O=C(O)CC1CCn2c1c(Sc1ccc(Cl)cc1)c1c(C(=O)C(F)(F)F)cc(F)cc12>>O=C(O)CC1CCn2c1c(Sc1ccc(Cl)cc1)c1c(C(O)C(F)(F)F)cc(F)cc12,,CO,,Cl,[BH4-].[Na+],test
US20110190489A1,Cc1ccc(S(=O)(=O)n2c(-c3cn(C)c4ccc(O)cc34)cc3c4c(cnc32)cnn4C)cc1.ClCCN1CCOCC1>>Cc1ccc(S(=O)(=O)n2c(-c3cn(C)c4ccc(OCCN5CCOCC5)cc34)cc3c4c(cnc32)cnn4C)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120040968A1,CC(C)(C)OC(=O)NC1CCC(=O)CC1.[Li]CC>>CCC1(O)CCC(NC(=O)OC(C)(C)C)CC1,,O,,C1CCOC1,,test
US20110306645A1,CS(N)(=O)=O.Cc1cccc(C(=O)O)c1N>>CC1(N)C=CC=CC1C(=O)NS(C)(=O)=O,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20020193367A1,C1=COCCC1.COC(=O)c1cccc(-c2nnc(CO)o2)c1.Cc1ccc(S(=O)(=O)O)cc1>>COC(=O)c1cccc(-c2nnc(COC3CCCCO3)s2)c1,,CCOC(C)=O,,O,,test
US05643927,CC(=O)c1ccc(O)cc1O.ClCCCBr>>CC(=O)c1ccc(OCCCCl)cc1O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090291950A1,COc1ccc2c(Cl)ccnc2c1OC1CCCC1.Nc1c(Cl)c(Cl)nc(Cl)c1Cl>>COc1ccc2c(Nc3c(Cl)c(Cl)nc(Cl)c3Cl)ccnc2c1OC1CCCC1,,CS(C)=O,,,,test
US20030078287A1,O=C(O)c1sccc1OC(F)F.O=S(Cl)Cl>>O=C(Cl)c1sccc1OC(F)F,,Cc1ccccc1,,,,test
US20040192914A1,C[Si](C)(C)C=[N+]=[N-].N#Cc1cc2ccccc2cn1>>C[Si](C)(C)c1[nH]nnc1-c1cc2ccccc2cn1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US04479955,CCOC(=O)c1cnc2ccncc2c1Cl.Cl.NNc1ccncc1>>CCOC(=O)c1cnc2ccncc2c1NNc1ccncc1.Cl,,CO,,,,test
US20070021450A1,O=Nc1c(NC2CCc3ccccc32)[nH]c(=O)[nH]c1=O>>Nc1c(NC2CCc3ccccc32)[nH]c(=O)[nH]c1=O,,O,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20070105846A1,CCCCC(=O)N(Cc1ccc(C2SC(=O)NC2=O)cc1)c1cccc(C(=O)OCC)c1>>CCCCC(=O)N(Cc1ccc(C2SC(=O)NC2=O)cc1)c1cccc(C(=O)O)c1,,CCO,,Cl,[Na+].[OH-],test
US20050267095A1,C1CSCCN1.ClCCCBr>>ClCCCN1CCSCC1,,CC(C)=O,,[Na+].[OH-],,test
US20100316656A1,COC(=O)CCCC#Cc1cc(C(C)(C)O[SiH2]C(C)(C)C)cc(C(C)(C)O[SiH2]C(C)(C)C)c1>>COC(=O)CCCC#Cc1cc(CO)cc(CO)c1,,C1CCOC1,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05728835,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCc1ccc(C(=O)Nc2ccccc2OC)cc1>>COc1ccccc1NC(=O)c1ccc(CN(C)C(=O)OC(C)(C)C)cc1,,C1COCCO1,O,[Na+].[OH-],,test
US20050113397A1,CCOC(=O)C(CCCN1C(=O)c2ccccc2C1=O)C(C)=O.N#CCc1nc2ccccc2[nH]1>>Cc1c(CCCN2C(=O)c3ccccc3C2=O)c(=O)n2c([nH]c3ccccc32)c1C#N,,O,,C,O=C[O-].[NH4+],test
US03934008,C[C@H](NC(=O)OCc1ccccc1)C(=O)Oc1ccc([N+](=O)[O-])cc1.NC(=O)[C@@H]1CCCN1>>C[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(N)=O,,CN(C)C=O,,,,test
US04399141,C=C1c2ccccc2CC(=NO)c2ccccc21>>C=C1c2ccccc2CC(NO)c2ccccc21,,CO,,[BH3-]C#N.[Na+],,test
US20080171743A1,C[C@H]1COCCN1c1cc(C(C)(C)S(=O)(=O)c2ccc(F)cc2)nc(-c2ccc(N)cc2)n1.O=C(Cl)Oc1ccccc1>>C[C@H]1COCCN1c1cc(C(C)(C)S(=O)(=O)c2ccc(F)cc2)nc(-c2ccc(NC(=O)Oc3ccccc3)cc2)n1,,C1COCCO1,,O=C([O-])O.[Na+],,test
US20110034445A1,CCCCCOC(=O)Cl.Cn1ccnc1C(=NOCc1nccc(N)n1)c1ccccc1>>CCCCCOC(=O)Nc1ccnc(CON=C(c2ccccc2)c2nccn2C)n1,,ClCCl,,CCN(CC)CC,,test
US04501735,N[C@@H]1CCc2ccccc21.OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O>>OC[C@H]1O[C@@H](n2cnc3c(N[C@@H]4CCc5ccccc54)ncnc32)[C@H](O)[C@@H]1O,,CCO,,CCN(CC)CC,,test
US20130225620A1,Clc1nccc(Nc2cc(C3CC3)[nH]n2)n1.Cn1ccc2cc(CN)ccc21>>Cn1ccc2cc(CNc3nccc(Nc4cc(C5CC5)[nH]n4)n3)ccc21,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20110190330A1,C=CC(C)(C)c1cc(COc2ccc3c(c2)[C@]2(CC3)C[C@H]2C(=O)OCC)ccc1-c1cc(OC)ncc1F>>C=CC(C)(C)c1cc(COc2ccc3c(c2)[C@]2(CC3)C[C@H]2C(=O)O)ccc1-c1cc(OC)ncc1F,,CO,,[Li+].[OH-],,test
US20150353553A1,CC(=O)c1ccccc1F.C[C@@H]1CC[C@@H](Cn2cnc3nc(C#N)nc(N[C@H](C)C4CCC4)c32)CC1>>C[C@@H]1CC[C@@H](Cn2c(C(C)(O)c3ccccc3F)nc3nc(C#N)nc(N[C@H](C)C4CCC4)c32)CC1,,C1CCOC1,,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US20160221972A1,COC(=O)c1ccc(CBr)c(Br)c1.C[C@H](O)CN>>COC(=O)c1ccc(CNC[C@H](C)O)c(Br)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20020055472A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](CO)Cc1ccccc1>>CC(C)(C)OC(=O)N[C@@H](CO)Cc1ccccc1,,ClCCl,,,,test
US04935515,CI.S=C1Nc2ccccc2N2CCN(c3ccccc3)CCN12>>CSC1=Nc2ccccc2N2CCN(c3ccccc3)CCN12,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20150210720A1,COC(=O)c1coc2c1C(=O)N(C)CC2>>CN1CCc2occ(C(=O)O)c2C1=O,,C1CCOC1,,Cl,,test
US20110201629A1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.CN(C)C=O.Cn1c(=O)n(CC2CCC(N)CC2)c2ccccc21.F[P-](F)(F)(F)(F)F.O=C(O)c1ccc(F)c(C(F)(F)F)c1>>Cn1c(=O)n(C[C@@H]2CC[C@@H](NC(=O)c3ccc(F)c(C(F)(F)F)c3)CC2)c2ccccc21.O=C(O)C(F)(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20100324030A1,Nc1cc(C2OCCCO2)ccc1O.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=c1[nH]c2cc(C3OCCCO3)ccc2o1,,CCN(CC)CC,ClCCl,,,test
US20130059846A1,Cc1ccc(-c2noc(C3CC4(CC(=O)C4)C3)n2)cc1NC(=O)c1cnc2ccccn12>>Cc1ccc(-c2noc(C3CC4(CC(O)C4)C3)n2)cc1NC(=O)c1cnc2ccccn12,,CO,,[BH4-].[Na+],,test
US20140221361A1,COC(=O)c1ccc(C2=CC[C@@]3(C)[C@@H](CC[C@]4(C)[C@@H]3CC[C@@H]3[C@H]5[C@H]([C@@H](C)N)CC[C@]5(NCCN5CCS(=O)(=O)CC5)CC[C@]34C)C2(C)C)cc1.O=C(O)C(F)(F)F>>CC(N)[C@@H]1CC[C@]2(NCCN3CCS(=O)(=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.O=C(O)C(F)(F)F,,C1CCOC1,CO,O,[Li+].[OH-],test
US04382942,BrCCc1ccccc1.COc1cccc(C2=CCCNC2)c1>>COc1cccc(C2=CCCN(CCc3ccccc3)C2)c1,,CC(C)=O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20150057238A1,O=C(OCCOC1CCCCO1)[C@H]1C[C@@H]1C(=O)c1ccc(Cl)c(Cl)c1>>O=C(OCCO)[C@H]1C[C@@H]1C(=O)c1ccc(Cl)c(Cl)c1,Cl,,,,,test
US06350749B1,Cc1coc2c1C(=O)CC(c1ccccc1F)C2.Cl.N=C(N)NN>>Cc1coc2c1/C(=N/NC(=N)N)CC(c1ccccc1F)C2.Cl,,CCO,,Cl,,test
US20130267493A1,COc1ccc(-c2cc3c(C(=O)O)n[nH]c3cc2Cl)cc1.Cc1ccc(O)cc1>>COc1ccc(-c2cc3c(C(=O)Oc4ccc(C)cc4)n[nH]c3cc2Cl)cc1,,O=S(Cl)Cl,,CCN(CC)CC,,test
US20100184770A1,CC(C)(C)OC(=O)NCCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O>>NCCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O,,C1COCCO1,,Cl,,test
US20030087874A1,CC(C)C(O)C(NC(=O)OCc1ccccc1)C(=O)NCCC=O.COc1ccc(Cn2c(=O)ccn([C@@H]3O[C@H]([C@H](O)[C@H](N)C(=O)OC(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]3O[Si](C)(C)C(C)(C)C)c2=O)cc1>>COc1ccc(Cn2c(=O)ccn([C@@H]3OC([C@H](O)[C@H](NCCCNC(=O)[C@@H](NC(=O)OCc4ccccc4)[C@@H](O)C(C)C)C(=O)OC(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]3O[Si](C)(C)C(C)(C)C)c2=O)cc1,CC(=O)O,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20070049593A1,COC(=O)c1ccc2c(C3CCCCC3)c(Br)[nH]c2c1.ClCSc1ccccc1>>COC(=O)c1ccc2c(C3CCCCC3)c(Br)n(CSc3ccccc3)c2c1,,CN(C)C=O,,O,[H-].[Na+],test
US20130123528A1,CC(C)(C)N1C=CN(C(C)(C)C)[SiH]1Cl.CC(C)N>>CC(C)N[SiH]1N(C(C)(C)C)C=CN1C(C)(C)C,,CCCCCC,,,,test
US20110183978A1,CC(C)I.CSc1nccc(-c2c[nH]nc2-c2ccc(F)cc2)n1>>CSc1nccc(-c2cn(C(C)C)nc2-c2ccc(F)cc2)n1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20040235822A1,CCCn1cncc1CCl.O=[N+]([O-])c1ccc2nc(S)[nH]c2c1>>CCCn1cncc1CSc1nc2ccc([N+](=O)[O-])cc2[nH]1,,CCO,,Cl,[Na+].[OH-],test
US09364481B2,COc1ccc2nc(Cl)c(C(F)(F)F)nc2c1.O=C(O)c1ccc(B(O)O)c(F)c1>>COc1ccc2nc(-c3ccc(C(=O)O)cc3F)c(C(F)(F)F)nc2c1,,O,,,,test
US20120302610A1,CCOC(=O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2C=O)cn1.Nc1ccc(Br)cc1F>>CCOC(=O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2CNc2ccc(Br)cc2F)cn1,,CCOC(C)=O,ClCCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090281103A1,NC1CC1.O=C(Cl)Cc1ccccc1>>c1ccc(CCNC2CC2)cc1,,C1CCOC1,ClCCl,c1ccncc1,,test
US20030153566A1,COc1ccc(N2C[C@@H]3C[C@H]2CO3)c2sc(N)nc12.Cc1cc(C(=O)Cl)ccn1>>COc1ccc(N2C[C@@H]3C[C@H]2CO3)c2sc(NC(=O)c3ccnc(C)c3)nc12,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,Cl,test
US07202238B2,O=C1CC[C@@H]2CN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@H](Cc3c[nH]c4ccccc34)CN2C1>>O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1C[C@H]2CC[C@H](O)CN2C[C@H]1Cc1c[nH]c2ccccc12,,CC(=O)O,O,[Na+].[OH-],,test
US20150152085A1,CN(C)N=O.N#Cc1ccccc1F>>Cn1cc(-c2ccccc2F)nn1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20160137636A1,COc1cc(Cl)c(F)cc1B1OC(C)(C)C(C)(C)O1.COc1ccc(CN(c2ccon2)S(=O)(=O)c2ccc3c(Cl)ncc(O)c3c2)cc1>>COc1ccc(CN(c2ccon2)S(=O)(=O)c2ccc3c(-c4cc(F)c(Cl)cc4OC)ncc(O)c3c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20070185078A1,CC(=O)Cl.COc1ccc2c(n1)CNCc1nnc(-c3ccc(-c4ccccc4OC)cc3)n1-2>>COc1ccc2c(n1)CN(C(C)=O)Cc1nnc(-c3ccc(-c4ccccc4OC)cc3)n1-2,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20130040935A1,Cc1ccc(Br)cc1C1=C(O)C2(CCC3(CC2)OCCO3)NC1=O>>Cc1ccc(Br)cc1C1=C(O)C2(CCC(=O)CC2)NC1=O,,CC(C)=O,O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100144722A1,Cn1cc(-c2cc(Cl)nc(Cl)n2)cn1.OC1CCNCC1>>Cl.Cn1cc(-c2cc(N3CCC(O)CC3)nc(Cl)n2)cn1,,CO,,CCN(C(C)C)C(C)C,,test
US20020040144A1,O=[N+]([O-])c1ccc(F)cc1.[N-]=[N+]=N[C@@H]1CCC[C@H]1O>>[N-]=[N+]=N[C@@H]1CCC[C@H]1Oc1ccc([N+](=O)[O-])cc1,,CN(C)C=O,,[H-].[Na+],,test
US20090118338A1,NC(=O)c1cccc(N)c1.O=C(Cl)c1ccccc1Br>>NC(=O)c1cccc(NC(=O)c2ccccc2Br)c1,,C1CCOC1,,CCN(CC)CC,,test
US04758587,CI.COc1cc(O)c2ccccc2c1OC(C)=O>>COc1cc(OC)c2ccccc2c1OC(C)=O,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20050026916A1,CNCc1ccccc1.CSC1=N[C@@H](c2ccccc2)[C@@H](c2ccccc2)N1C(=O)OC(C)(C)C>>CN(Cc1ccccc1)C1=N[C@@H](c2ccccc2)[C@@H](c2ccccc2)N1C(=O)OC(C)(C)C,,ClCCl,,CO,,test
US05716543,CCCCC[C@@H]1CC[C@@H](CO)CC1.Oc1cc(F)c(F)c(F)c1>>CCCCC[C@@H]1CC[C@@H](COc2cc(F)c(F)c(F)c2)CC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030162972A1,O=C(CCc1cccnc1)NCCCCC1CCNCC1.O=P(Cl)(c1ccccc1)c1ccccc1>>O=C(CCc1cccnc1)NCCCCC1CCN(P(=O)(c2ccccc2)c2ccccc2)CC1,,C1CCOC1,,,,test
US20090163709A1,CCOCOc1ccc(O)c(OCOCC)c1.CI>>CCOCOc1ccc(OC)c(OCOCC)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090325964A1,CCOC(=O)c1cccc(C#Cc2ccccc2)c1>>O=C(O)c1cccc(C#Cc2ccccc2)c1,,CO,,[Na+].[OH-],,test
US05200116,CC(=O)Cc1ccccc1.CCOC(=O)CBr>>CCOC(=O)CC(C)(O)Cc1ccccc1,[Zn],Cc1ccccc1,,,,test
US20070244164A1,Cc1c(Nc2ccc(I)cc2F)c(NS(=O)(=O)C2(CCO[Si](C)(C)C(C)(C)C)CC2)cn(C)c1=O>>Cc1c(Nc2ccc(I)cc2F)c(NS(=O)(=O)C2(CCO)CC2)cn(C)c1=O,,C1CCOC1,,Cl,,test
US20050107425A1,CCOC(=O)c1ccc2c(c1)C=CCO2>>O=C(O)c1ccc2c(c1)C=CCO2,,CO,,[Na+].[OH-],,test
US20100009975A1,CN(CCN1CCSc2cc([N+](=O)[O-])ccc21)CC(=O)OC(C)(C)C>>CN(CCN1CCSc2cc(N)ccc21)CC(=O)OC(C)(C)C,[Pd],CCO,,,,test
US20090030041A1,Cc1cc(C)c(CCl)c(C)c1.O=C(O)C(CO)c1cccs1>>Cc1cc(C)c(COC(=O)C(CO)c2cccs2)c(C)c1,,CN(C)C=O,,O,[K+].[OH-],test
US20020035272A1,CCCCc1oc2ccccc2c1/C=C\c1ccc(OC)cc1>>CCCCc1oc2ccccc2c1CCc1ccc(OC)cc1,[Pd],CCOC(C)=O,,,,test
US20080119521A1,Cn1cc(C(=O)O)c2ccccc21.NCCC1CCN(Cc2ccccc2)CC1.O=C(n1ccnc1)n1ccnc1>>Cn1cc(CC(=O)NCCC2CCN(Cc3ccccc3)CC2)c2ccccc21,,C1CCOC1,,,,test
US20150038437A1,CCc1cc(C(=O)OC)c(=O)n(Cc2ccc(OC)cc2OC)c1-c1ccc2c(c1)cc(CCO)n2C.CS(=O)(=O)Cl>>CCc1cc(C(=O)OC)c(=O)n(Cc2ccc(OC)cc2OC)c1-c1ccc2c(c1)cc(CCOS(C)(=O)=O)n2C,,ClCCl,,CCN(CC)CC,,test
US20140296136A1,COC(=O)[C@@H]1C[C@@H](Oc2nc3ccccc3c(OCc3ccccc3)c2C#CCCC[C@@H]2C[C@H]2OC(=O)N[C@H](C(=O)Cl)C(C)(C)C)C[NH2+]1>>COC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C(C)(C)C)NC(=O)O[C@@H]1C[C@H]1CCCC#Cc1c(nc3ccccc3c1OCc1ccccc1)O2,,CCOCC,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140155428A1,COc1ccc([C@@H](O)Cc2c(Cl)c[n+]([O-])cc2Cl)cc1OC.O=Cc1ccc(C(=O)O)cc1>>COc1ccc([C@H](Cc2c(Cl)c[n+]([O-])cc2Cl)OC(=O)c2ccc(C=O)cc2)cc1OC,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20130059834A1,CC1(NS(=O)C(C)(C)C)CC(NC(=O)OC(C)(C)C)C1.Cl>>CC1(N)CC(NC(=O)OC(C)(C)C)C1.Cl,,C1COCCO1,CO,,,test
US20140249196A1,CCC(N)c1ccccc1.O=C(O)c1ccc2nc[nH]c2c1>>CCC(NC(=O)c1ccc2[nH]cnc2c1)c1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05986115,Cc1ccc(S(=O)(=O)OCCCCC[C@@H]2Cc3cc(OCc4ccccc4)ccc3[C@H]3CC[C@]4(C)C(=O)CC[C@H]4[C@H]23)cc1.FC(F)(F)C(F)(F)CCCSC[C@@H]1CCCN1>>C[C@]12CC[C@@H]3c4ccc(OCc5ccccc5)cc4C[C@@H](CCCCCN4CCC[C@H]4CSCCCC(F)(F)C(F)(F)F)[C@H]3[C@@H]1CCC2=O,,CCCCCC,CCOC(C)=O,,,test
US20030166639A1,CC(C)(C)OC(=O)Nc1ccc(C(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-c2cccnc2)c1>>O=C1CC(c2cccc(-c3cccnc3)c2)=Nc2ccc(C(F)(F)F)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04804668,COC(=O)c1nc(C)c(-c2ccncc2)s1.Nc1ccccc1>>Cc1nc(C(=O)Nc2ccccc2)sc1-c1ccncc1,,C1CCOC1,,[Li]CCCC,,test
US20110160243A1,CC(C)(C)OC(=O)CC1CCn2c1cc1cc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)ccc12.O=C1CCC(=O)N1I>>CC(C)(C)OC(=O)CC1CCn2c1c(I)c1cc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)ccc12,,ClCCl,,,,test
US06346625B1,Cn1cc(-c2c(C#N)n(C(=O)OC(C)(C)C)c(=O)n2-c2c[nH]c3ccccc23)c2ccccc21.O=C1c2ccccc2C(=O)N1CCCBr>>Cn1cc(-c2c(C#N)n(C(=O)OC(C)(C)C)c(=O)n2-c2cn(CCCN3C(=O)c4ccccc4C3=O)c3ccccc23)c2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130225580A1,CCC(C)(C)c1ccc(S(=O)(=O)Cl)cc1.Cc1cc(N)n(-c2cccc3ncccc23)n1>>Cc1cc(NS(=O)(=O)c2ccc(C(C)C)cc2)n(-c2cccc3ncccc23)n1,,c1ccncc1,,ClCCl,,test
US20090156600A1,CCC(=O)CC(=O)OC.Fc1ccc(CBr)c(Cl)c1>>CCC(=O)C(Cc1ccc(F)cc1Cl)C(=O)OC,,C1CCOC1,O,CC(C)(C)O,CC(C)(C)[O-].[K+],test
US20090054463A1,CC(C)(C)NS(=O)(=O)c1ccc(-c2nc(NC(=O)N(CCc3ccccn3)CCC(c3ccccc3)c3ccccc3)sc2Cl)cc1>>NS(=O)(=O)c1ccc(-c2nc(NC(=O)N(CCc3ccccn3)CCC(c3ccccc3)c3ccccc3)sc2Cl)cc1,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US20010037030A1,O=C1C=CC2CN(Cc3ccccc3)CC12>>O=C1CCC2CN(Cc3ccccc3)CC12,[Rh],CCOC(C)=O,,[H][H],,test
US20110021520A1,Brc1cccc(I)c1.CCOC(=O)C(F)F>>O=C(c1cccc(Br)c1)C(F)F,,C1CCOC1,,[Li]CCCC,,test
US20090099169A1,COC(=O)c1ccc(C(=O)Nc2cc(C)n(Cc3cc(Cl)cc4cc(C(C)C)oc34)n2)cc1>>Cc1cc(NC(=O)c2ccc(CO)cc2)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12,,C1CCOC1,CCOCC,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130137709A1,CNC(=O)c1ccccc1Nc1nc(Nc2cc([N+](=O)[O-])cc(C(F)(F)F)c2)ncc1Cl>>CNC(=O)c1ccccc1Nc1nc(Nc2cc(N)cc(C(F)(F)F)c2)ncc1Cl,[Fe],O,,CCO,[Cl-].[NH4+],test
US05952327,CC(C)(C)C(=O)OCCl.CCOC(=O)CN1C(=O)[C@@H](NC(=O)C2(CP(=O)(O)OCC)CCCC2)CCc2ccccc21>>CCOC(=O)CN1C(=O)[C@@H](NC(=O)C2(C(CC)(COC(=O)C(C)(C)C)P(=O)(O)O)CCCC2)CCc2ccccc21,,CN(C)C=O,,CCN(CC)CC,CN(C)c1ccccn1,test
US20040132726A1,CC=O.CCOC(=O)N1CCNCC1.C[N+](=O)[O-]>>CCOC(=O)N1CCN(C(C)C[N+](=O)[O-])CC1,,C1CCOC1,CCO,CC(C)(C)[O-].[K+],,test
US20100160388A1,CSc1cc(N)c(Br)cc1Cl.O=C(Cl)Cl>>CSc1cc(N=C=O)c(Br)cc1Cl,CN(C)c1ccncc1,Cc1ccccc1,,c1ccncc1,,test
US06175007B1,CI.CON=Cc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c(F)cc1Cl>>CON=Cc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130029961A1,CC(C)(C)[Si](C)(C)Cl.Nc1ccc(CO)cn1>>CC(C)(C)[Si](C)(C)OCc1ccc(N)nc1,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US20100081825A1,CC(C)(C)[Si](C)(C)Oc1ccc2ccc(O)cc2c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)[Si](C)(C)Oc1ccc2ccc(OS(=O)(=O)C(F)(F)F)cc2c1,,ClC(Cl)Cl,,O,,test
US04801603,CC(Br)Br.NC(=O)CCC(N)=O>>O=C1CCC(=O)N1CCBr,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050043388A1,NNC(=O)c1cccc([N+](=O)[O-])c1.O=C1Nc2ccc(I)cc2C1=O>>O=C1Nc2ccc(I)cc2C1=NNC(=O)c1cccc([N+](=O)[O-])c1,,CC(=O)O,,,,test
US20090215758A1,O=C1CSC(N2CCN(Cc3ccccc3)CC2)=N1.O=Cc1ccc(S(F)(F)(F)(F)F)cc1>>O=C1N=C(N2CCN(Cc3ccccc3)CC2)SC1=Cc1ccc(S(F)(F)(F)(F)F)cc1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20020052376A1,CC(C)(C)OC(=O)[C@H](CCS(C)(=O)=O)NC(=O)c1cc(OC(Cn2ccnc2)c2ccc(F)cc2)ccc1CCc1ccc(F)cc1>>CCCC(C)C.CCOCC,,O=C(O)C(F)(F)F,,,,test
US20060040957A1,ClCc1ccc(Cl)c(Cl)c1.O=c1cc2sccn2c(=O)[nH]1>>O=c1cc2sccn2c(=O)n1Cc1ccc(Cl)c(Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05342846,C[C@H]1COc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23.Cc1cn(C2CCNC2)nn1>>Cc1cn(C2CCN(c3c(F)cc4c(=O)c(C(=O)O)cn5c4c3OC[C@@H]5C)C2)nn1,,CC#N,,C1CCC2=NCCCN2CC1,Cl,test
US20090111808A1,ClCCCBr.Oc1ccc(-c2ccc(Br)cc2)cc1>>ClCCCOc1ccc(-c2ccc(Br)cc2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120065214A1,CCN.Cc1ccc(C(=O)O)cc1-n1ccnc(NC(C)(C)c2ccccc2OCCN(C)C(=O)OCc2ccccc2)c1=O>>CCNC(=O)c1ccc(C)c(-n2ccnc(NC(C)(C)c3ccccc3OCCN(C)C(=O)OCc3ccccc3)c2=O)c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20110257148A1,CC(C)(C)OC(=O)N1CC(O)(c2cc(F)cc(Cl)c2)C1>>OC1(c2cc(F)cc(Cl)c2)CNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030055044A1,FC(F)(F)c1ccccc1-c1cc2ccccc2c(Cl)n1.Nc1nc[nH]n1>>FC(F)(F)c1ccccc1-c1cc2ccccc2c(Nc2nc[nH]n2)n1,,CCO,,,,test
US20160175284A1,C1=COCCC1.O=C(Cc1ccc(F)cc1)c1c(O)ccc(O)c1F>>O=C(Cc1ccc(F)cc1)c1c(O)ccc(OC2CCCCO2)c1F,,ClCCl,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20080275018A1,CI.COC(=O)[C@H](Cc1cccc(Br)c1)NC(=O)OC(C)(C)C>>COC(=O)[C@H](Cc1cccc(Br)c1)N(C)C(=O)OC(C)(C)C,,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US20040138065A1,ClCCBr.N#CC(C#N)Cc1cccc(Cl)c1>>N#CC(C#N)(CCCl)Cc1cccc(Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120270865A2,CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2sc3ccncc3c2C)C2CCCCC2)cc1>>Cc1c(C(Nc2ccc(C(=O)N(C)CCC(=O)O)cc2)C2CCCCC2)sc2ccncc12,,CCO,,C1CCOC1,,test
US20030092720A1,COc1c(CCc2nc(C(C)C)cs2)ccn2c(=O)c(/C=C/C(=O)OC(C)(C)C)c(N3CCOCC3)nc12>>COc1c(CCc2nc(C(C)C)cs2)ccn2c(=O)c(/C=C/C(=O)O)c(N3CCOCC3)nc12,,O=C(O)C(F)(F)F,,,,test
US04211783,CCCCCCCCc1ccc(C=O)s1.CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCCCCCCCc1ccc(C=CC(=O)OCC)s1,,C1CCOC1,,,,test
US20070265289A1,CC(C)(C)OC(=O)N1CCCC(c2cc(-c3c(O)cccc3O)nc(N)n2)C1.CC1(C)OCC(CO)O1>>CC(C)(C)OC(=O)N1CCCC(c2cc(-c3c(O)cccc3OCC(O)CO)nc(N)n2)C1,,C1CCOC1,Cc1ccccc1,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070105880A1,Cl.NC(=O)C1CCCO1>>Cl.NC(=O)C1CCCO1,,CO,,,,test
US20140066488A1,CCC[C@H](O)[C@@H](O)C(=O)OCC.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>CCC[C@H](O)[C@@H](OS(=O)(=O)c1ccc([N+](=O)[O-])cc1)C(=O)OCC,,ClCCl,O,CCN(CC)CC,,test
US20070078135A1,O=C1CCC(=O)N1Br.O=C1c2ccccc2C(=O)N1C1CCN(c2cncc(-c3ccncc3Cl)n2)CC1>>O=C1c2ccccc2C(=O)N1C1CCN(c2cnc(Br)c(-c3ccncc3Cl)n2)CC1,,ClC(Cl)Cl,,,,test
US20070244086A1,Cn1nccc1-c1cc(N)ccc1OCCN1CCC1.O=C=Nc1ccc(F)cc1F>>Cn1nccc1-c1cc(NC(=O)Nc2ccc(F)cc2F)ccc1OCCN1CCC1,,ClCCl,,,,test
US20040102450A1,CC1CN(Cc2ccc3c(Cl)ccnc3c2)C(=O)[C@H](C)N1.Clc1ccc(C=CCBr)s1>>C[C@@H]1CN(Cc2ccc3c(Cl)ccnc3c2)C(=O)[C@H](C)N1CC=Cc1ccc(Cl)s1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080188487A1,CC(C)CS(=O)(=O)[O-].CCOC(=O)c1cc2cc(C(=O)N3CCCN(C(=O)OC(C)(C)C)CC3)ccc2[nH]1>>CCOC(=O)c1cc2cc(C(=O)N3CCCN(C(=O)OC(C)(C)C)CC3)ccc2n1C(C)C,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05795887,O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)OCc1ccccc1>>NC1N=C(c2ccccc2)c2ccccc2NC1=O,,CC(=O)O,CCOCC,Br,,test
US20120142668A1,CC[C@@H](/C=C/C(=O)OC)NC(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CC[C@H](N)/C=C/C(=O)OC.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20100234351A1,CC(C)(O)COCCO.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCCOCC(C)(C)O)cc1,,c1ccncc1,,O,,test
US20140088117A1,Cn1ncc([N+](=O)[O-])c1C1CCC=CCO1.O=C(OO)c1cccc(Cl)c1>>Cn1ncc([N+](=O)[O-])c1C1CCC2OC2CO1,,ClCCl,,,,test
US20050096348A1,Cc1nc(NCCNC(=O)OC(C)(C)C)sc1C>>Cc1nc(NCCN)sc1C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050239776A1,O=C(c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-n1ccnc1)c1c(CO)noc1-c1ccccc1Cl>>N#CC(C(=O)c1ccccc1Cl)C(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-n1ccnc1,,CCOC(C)=O,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20080194841A1,C=C[C@@H](C)[C@@H](C)/C(=C/C(=O)OCC)NC(C)=O>>CCOC(=O)C[C@@H](NC(C)=O)[C@H](C)[C@H](C)CC,[Pd],CO,,,,test
US20120178946A1,COc1cc(F)c(F)c(Nc2ccc(I)cc2F)c1NS(=O)(=O)C1(C[C@@H]2COC(C)(C)O2)CC1>>COc1cc(F)c(F)c(Nc2ccc(I)cc2F)c1NS(=O)(=O)C1(C[C@@H](O)CO)CC1,,C1CCOC1,Cl,,,test
US05521197,Fc1ccc2[nH]cc(C3=CCNCC3)c2c1>>Fc1ccc2[nH]cc(C3CCNCC3)c2c1,[Pd],CCO,,[H][H],,test
US05998433,C=O.CNC.c1ccc(CCCCCCN2CCCc3ccoc3C2)cc1>>CN(C)Cc1cc2c(o1)CN(CCCCCCc1ccccc1)CCC2,,CC(=O)O,,,,test
US20090198064A1,CCCCN(C(=O)Cl)c1ccccc1.O[C@H]1C[N+]2(CC=Cc3ccccc3)CCC1CC2.[Br-]>>CCCCN(C(=O)O[C@H]1C[N+]2(CC=Cc3ccccc3)CCC1CC2)c1ccccc1.[Br-],,CCCCCC,,,,test
US20100016164A1,O=C(CC(O)c1ccccc1)NCc1ccccc1[N+](=O)[O-]>>O=[N+]([O-])c1ccccc1CNCCC(O)c1ccccc1,,C1CCOC1,,B,CO,test
US20150266874A1,C[Si](C)(C)CCOCn1cc(C(=O)NC2CCOCC2)c(-c2nc3c(s2)CCCC3)n1>>O=C(NC1CCOCC1)c1c[nH]nc1-c1nc2c(s1)CCCC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US04053601,CC(C)(C)NCC(O)COc1ccc(C#N)cc1C1=NNC(=O)CC1>>CC(C)(C)NCC(O)COc1ccc(C#N)cc1-c1ccc(=O)[nH]n1,,CCCCO,,,,test
US20120295903A1,Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCCCCBr)c2cc1C.Nc1cc[nH]c(=O)n1>>Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCCCCn3ccc(N)nc3=O)c2cc1C,,CN(C)C=O,,[H-].[Na+],,test
US20160152609A1,CCOC(=O)c1nc(Br)n2c1CCc1cc(OC)c([N+](=O)[O-])cc1-2.OB(O)c1cccs1>>CCOC(=O)c1nc(-c2cccs2)n2c1CCc1cc(OC)c([N+](=O)[O-])cc1-2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20150266883A1,CCCCc1nc(Cl)c2[nH]cc(I)c2n1.ClCOCc1ccccc1>>CCCCc1nc(Cl)c2c(n1)c(I)cn2COCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20050288308A1,CC(C)c1nccc(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)n1.CN(C)C(=O)CCl>>CC(C)c1nccc(N(CC(=O)N(C)C)S(=O)(=O)c2ccc(Cl)c(Cl)c2)n1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090186882A1,CCC(Br)C(=O)O.Nc1ccccc1O>>CCC1Oc2ccccc2NC1=O,,CN(C)C=O,O,ClCCCl,On1nnc2ccccc21,test
US20100324040A1,CC(C)(C)S(=O)N[C@@H](CO[Si](C)(C)C(C)(C)C)c1ccc(F)cn1.Cl>>Cl.N[C@@H](CO)c1ccc(F)cn1,,CO,,,,test
US20140228349A1,CC(C)(C)OC(=O)N1CC(CCOS(C)(=O)=O)(n2cc(Br)cn2)C1>>C=CC1(n2cc(Br)cn2)CN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04820703,CC(C)Cc1ccc(CCCCc2cc3c(s2)NC(=O)CN=C3c2ccccc2Cl)cc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)Cc1ccc(CCCCc2cc3c(s2)NC(=S)CN=C3c2ccccc2Cl)cc1,,Cc1ccccc1,,,,test
US05668208,C1CCCCC1.C=Cc1ccccc1.CCCCCC>>C=CC(=C)C.C=Cc1ccccc1,,CCCCCC,,C1CCOC1,[Li]CCCC,test
US20060035912A1,CC(C)n1cc(C(=O)c2cccc(N)n2)c2c(N)ncnc21.O=S(=O)(Cl)c1ccccc1F>>CC(C)n1cc(C(=O)c2cccc(NS(=O)(=O)c3ccccc3F)n2)c2c(N)ncnc21,,c1ccncc1,,,,test
US20140336376A1,CO.Fc1cc(Br)c2oc(CBr)cc2c1F>>COCc1cc2c(F)c(F)cc(Br)c2o1,,CO,,C[O-].[Na+],,test
US20150369812A1,CN(C)c1ccc(/C=C/C(=O)c2ccccc2O)cc1.OO>>CN(C)c1ccc(-c2oc3ccccc3c(=O)c2O)cc1,,CCO,,[Na+].[OH-],,test
US20160096827A1,N#Cc1cc(-c2ncnc(Nc3ccc(C4CCN(C5COC5)CC4)cc3)n2)ccc1O[C@H]1CCNC[C@H]1F.O=C(O)CO>>N#Cc1cc(-c2ncnc(Nc3ccc(C4CCN(C5COC5)CC4)cc3)n2)ccc1O[C@H]1CCN(C(=O)CO)C[C@H]1F,,ClCCl,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05716624,C#C[Si](C)(C)C.CC1(C)CCC(C)(C)c2cc(C=O)ccc21>>CC1(C)CCC(C)(C)c2c1ccc(CO)c2C#C[Si](C)(C)C,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20110021522A1,COc1cccc2cc(C(=O)O)c(=O)oc12.Nc1cccc(-c2cncnc2)c1>>COc1cccc2cc(C(=O)Nc3cccc(-c4cncnc4)c3)c(=O)oc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05932599,CC(=O)Nc1ccc(S(N)(=O)=O)cc1.Nc1nc(Cl)cc(Cl)n1>>CC(=O)Nc1ccc(S(=O)(=O)Nc2cc(Cl)nc(N)n2)cc1,,CN1CCCC1=O,,[K],,test
US20100160302A1,CCN(CC)S(F)(F)F.COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C>>COC(=O)[C@@H]1C[C@H](F)CN1C(=O)OC(C)(C)C,,ClCCCl,,O=C([O-])O.[Na+],,test
US20080188528A1,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)c2cccn(Cc3ccccc3-c3cccc(C(C)C)c3)c2=O)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2.O=C(O)C(F)(F)F>>CC(C)c1cccc(-c2ccccc2Cn2cccc(C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)c2=O)c1.O=C(O)C(F)(F)F,,O,,CC[SiH](CC)CC,,test
US20120010190A1,Cc1cc(Cl)ccc1C(CC(=O)c1ccc(=O)n(C)c1)c1ccc(C(=O)O)cc1.NC[C@@H](O)CO>>Cc1cc(Cl)ccc1C(CC(=O)c1ccc(=O)n(C)c1)c1ccc(C(=O)NC[C@@H](O)CO)cc1,,C1CCOC1,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US04745116,CCC1(O)C=COC(=O)C1.COS(=O)(=O)OC>>CCc1cc(OC)cc(=O)o1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05397787,CI.O=C1Nc2ccccc2/C1=C/c1c[nH]c2ncccc12>>Cn1cc(/C=C2\C(=O)Nc3ccccc32)c2cccnc21,,CN(C)C=O,,[H][H],[H-].[Na+],test
US20140088101A1,CN.COC(=O)c1ncc2c(c1O)CCN(Cc1ccc(OC)cc1OC)C2=O>>CNC(=O)c1ncc2c(c1O)CCN(Cc1ccc(OC)cc1OC)C2=O,,CCO,,,,test
US20030153556A1,CC(C)(C)OC(=O)N1CCNCC1.CCN(C(C)C)C(C)C.O=C(Cl)Cc1ccccc1>>CC(C)(C)OC(=O)N1CCN(NC(=O)Cc2ccccc2)CC1,,ClCCl,,,,test
US20140066424A1,COCCBr.Cc1nc(-c2nc(-c3ccc(OC(F)(F)F)cc3)cs2)nn1Cc1cccc(O)c1>>COCCOc1cccc(Cn2nc(-c3nc(-c4ccc(OC(F)(F)F)cc4)cs3)nc2C)c1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070238726A1,Clc1ccc(CBr)cc1.O=c1[nH]cncc1Br>>O=c1c(Br)cncn1Cc1ccc(Cl)cc1,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US04714619,C[C@@H](NC(=O)OCc1ccccc1)C(=O)OC12CC3CC(CC(C3)C1)C2.Cl>>C[C@@H](N)C(=O)OC12CC3CC(CC(C3)C1)C2.Cl,[Pd],CO,,CCOCC,,test
US20050124586A1,CC(C)(C)[Si](C)(C)Cl.CCOP(=O)(Cc1cc(C)c(O)c(OC)c1)OCC>>CCOP(=O)(Cc1cc(C)c(O[Si](C)(C)C(C)(C)C)c(OC)c1)OCC,,CN(C)C=O,,c1c[nH]cn1,,test
US20080194617A1,CC(C)O.CCOC(=O)/C=C/c1c(C)nn(C)c1-n1ccc2ccc(O)cc21>>CCOC(=O)/C=C/c1c(C)nn(C)c1-n1ccc2ccc(OC(C)C)cc21,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20040214832A1,COc1ccc(COC[C@H]2CN(Cc3ccccc3)CCN2c2ccc(OCc3ccccc3)cc2)cc1>>OCC1CN(Cc2ccccc2)CCN1c1ccc(OCc2ccccc2)cc1,,O=C(O)C(F)(F)F,,ClCCl,,test
US20090137595A1,CC(C)(C#N)c1cccc(N)c1.O=C(O)c1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1>>CC(C)(C#N)c1cccc(NC(=O)c2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)c2)c1,CN(C)c1ccncc1,c1ccncc1,,CCN=C=NCCCN(C)C,Cl,test
US20030171428A1,COc1ccc(-c2cc3cc(Br)ccc3o2)cc1>>Oc1ccc(-c2cc3cc(Br)ccc3o2)cc1,,O,,Cl,c1ccncc1,test
US20100190764A1,CCOC(=O)C1CCN(C2CCC3(C2)C(=O)c2cc(F)ccc2Sc2ccccc23)CC1>>O=C(O)C1CCN(C2CCC3(C2)C(=O)c2cc(F)ccc2Sc2ccccc23)CC1,,Cl,O,,,test
US05252735,ClCc1cccnc1.O=c1cc(-c2ccc(O)cc2)oc(N2CCOCC2)c1>>O=c1cc(-c2ccc(OCc3cccnc3)cc2)oc(N2CCOCC2)c1,,CN(C)C=O,,Cl,[H-].[Na+],test
US03953595,CC(=O)CCl.O=C(O)c1cc(Cl)ccc1O>>CC(=O)COc1ccc(Cl)cc1C(=O)O,,O,,CCO,[Na+].[OH-],test
US05270309,Cc1cc(Br)cc([N+](=O)[O-])c1>>Cc1cc(N)cc(Br)c1,[Fe],CCO,,CC(=O)O,O,test
US20160218303A1,Cc1ccc(Nc2cc(C#N)ccc2[N+](=O)[O-])cc1C>>Cc1ccc(Nc2cc(C#N)ccc2N)cc1C,,CCO,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20020099047A1,Cl.c1ccc2c(c1)COc1ccccc1N2[C@@H]1CCN(CCc2ccc3c(c2)OCO3)C1>>Cl.c1ccc2c(c1)COc1ccccc1N2[C@@H]1CCN(CCc2ccc3c(c2)OCO3)C1,,ClCCl,,CCOCC,,test
US20150018352A1,CC(C)(C)OC(=O)N1CC=C(c2cc(C(F)(F)F)ccc2-c2cccc3c2CCN(S(=O)(=O)Nc2ncns2)C3)CC1.Cl>>Cl.O=S(=O)(Nc1ncns1)N1CCc2c(cccc2-c2ccc(C(F)(F)F)cc2C2=CCNCC2)C1,,CCOCC,,C1COCCO1,,test
US20060252730A1,CCCn1c(=O)c2[nH]c(C34CCC(CCC(=O)O)(CC3)CC4)nc2n(CCC)c1=O.N>>CCCn1c(=O)c2[nH]c(C34CCC(CCC(N)=O)(CC3)CC4)nc2n(CCC)c1=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080009490A1,CNCCC1CN(Cc2ccc(F)cc2)C(=O)c2c(OC(C)=O)c(=O)n(C(C)C)c(=O)n21.CS(=O)(=O)Cl>>CC(C)n1c(=O)c(O)c2n(c1=O)C(CCN(C)S(C)(=O)=O)CN(Cc1ccc(F)cc1)C2=O,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20130225588A1,COC(=O)Cc1cc2ccc(Cl)cc2c(-c2ccc(N)cc2)c1C.Cc1ccccc1S(=O)(=O)Cl>>COC(=O)Cc1cc2ccc(Cl)cc2c(-c2ccc(NS(=O)(=O)c3ccccc3C)cc2)c1C,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20120277224A1,COC(=O)CC(=O)c1ccc2c(c1)CCO2.Nc1[nH]ncc1-c1ccccn1>>O=c1cc(-c2ccc3c(c2)CCO3)[nH]c2c(-c3ccccn3)cnn12,,CC(=O)O,,,,test
US04846882,O=C1C2=C(CCCC2)C(=O)N1c1cc(CO)c(Cl)cc1F.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)Oc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl,,CCOC(C)=O,,CCN(CC)CC,CO,test
US20120065195A1,CC1(C)Cc2ccc(Br)cc2C2(CCOC(N)=N2)C1.OB(O)c1cncnc1>>CC1(C)Cc2ccc(-c3cncnc3)cc2C2(CCOC(N)=N2)C1,,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US05538984,BrCc1ccccc1.CC(C)(C)OC(=O)N1CCC(CCc2noc3c4c(ccc23)NC(=O)C4)CC1>>O=C1Cc2c(ccc3c(CCC4CCN(Cc5ccccc5)CC4)noc23)N1,,CN(C)C=O,ClCCl,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],test
US20110015196A1,CCN1CCN(C(=O)[C@@H]2C[C@H](NC(=O)OCc3ccccc3)C2(C)C)CC1>>CCN1CCN(C(=O)[C@@H]2C[C@H](N)C2(C)C)CC1,,CCOC(C)=O,,,,test
US20080004309A1,CCOC(=O)CNC(=O)OC(C)(C)C.CCOC(=O)c1sc(-c2ccc(Cl)cc2)nc1CBr>>CCOC(=O)CN(Cc1nc(-c2ccc(Cl)cc2)sc1C(=O)OCC)C(=O)OC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US04261999,OCC1Cc2sccc2CN1.S=C=Nc1cccc2cnccc12>>OCC1Cc2sccc2CN1C(=S)Nc1cccc2cnccc12,,CCO,,,,test
US20160221945A1,CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)NCc1cc(-c2ccc(C(F)(F)F)nc2)nc(-c2ccc(C(F)(F)F)nc2)c1.Cl>>Cl.O=C(NCc1cc(-c2ccc(C(F)(F)F)nc2)nc(-c2ccc(C(F)(F)F)nc2)c1)[C@@H]1C[C@@H](F)CN1,,C1COCCO1,ClCCl,,,test
US08309542B2,CC1=NCCc2ccsc21.CI>>CC1=[N+](C)CCc2ccsc21.[I-],,CCOC(C)=O,,,,test
US20070213298A1,CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Cc1ccccc1.Clc1cc(Cl)c(-c2ccccc2)cc1Cl.Clc1ccc(-c2ccccc2)c(Cl)c1Cl.O>>CCC=CCC=CCC=CCC=CCC=CC/C=C\CCC(=O)O,,Cc1ccccc1,,Cl,,test
US06479487B1,CCCCCCCCCCCCN.Clc1nc(Cl)c2ncn(C3CCCC3)c2n1>>CCCCCCCCCCCCNc1nc(Cl)nc2c1ncn2C1CCCC1,,CCN(CC)CC,,,,test
US20110065706A1,CC(C)c1nc(N2CCN(C(=O)OC(C)(C)C)[C@H](C)C2)no1>>CC(C)c1nc(N2CCN[C@H](C)C2)no1,,ClCCl,,C1COCCO1,Cl,test
US20150344423A1,COC(=O)c1cc(C=O)c[nH]1.Cl[Mg]C1CCCCC1>>COC(=O)c1cc(C(O)C2CCCCC2)c[nH]1,,C1CCOC1,,,,test
US20140296200A1,CN(CCCNC(=O)c1ccc(-n2ncc(-c3ccc(C#N)cc3)c2O)nc1)C(=O)OC(C)(C)C.Cl>>CNCCCNC(=O)c1ccc(-n2ncc(-c3ccc(C#N)cc3)c2O)nc1.Cl,,CCOC(C)=O,,,,test
US03966801,CCOC(=O)C(O)CCc1ccc(C2CCCCC2)c(N)c1.O=N[O-]>>O=C(O)C(O)CCc1ccc(C2CCCCC2)c(O)c1,,O,,Cl,,test
US05750549,CC(C)I.O=Cc1cc(Br)ccc1O>>CC(C)Oc1ccc(Br)cc1C=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100311732A1,CN1C(=O)CN(C(=O)OC(C)(C)C)Cc2ccccc21.O=C(O)C(F)(F)F>>CN1C(=O)CNCc2ccccc21.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20110152519A1,C=O.CC#N.Nc1c(N2CCOCC2)nc(N2CCN(c3ccccc3)CC2)nc1N1CCOCC1>>CN(C)c1c(N2CCOCC2)nc(N2CCN(c3ccccc3)CC2)nc1N1CCOCC1,,CC#N,CC(=O)O,[Na+].[OH-],,test
US04381304,CCOC(=O)CBr.CCOC(=O)c1c[nH]c2c(=O)ccccc2c1=O>>CCOC(=O)Cn1cc(C(=O)OCC)c(=O)c2ccccc(=O)c21,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20090137548A1,COC(=O)c1ccc(-c2ccc(OC)c(-c3ccc(C(F)(F)F)cc3[C@H]3OC(=O)N[C@@H]3C)c2)c(C)c1.FC(F)(F)c1cc(CBr)cc(C(F)(F)F)c1>>COC(=O)c1ccc(-c2ccc(OC)c(-c3ccc(C(F)(F)F)cc3[C@H]3OC(=O)N(Cc4cc(C(F)(F)F)cc(C(F)(F)F)c4)[C@@H]3C)c2)c(C)c1,,C1CCOC1,,[H-].[Na+],,test
US05750550,C=C(C)C.O=C(O)c1cc(O)n(-c2ccccc2)n1>>CC(C)(C)OC(=O)c1cc(O)n(-c2ccccc2)n1,,C1COCCO1,,O=S(=O)(O)O,[Na+].[OH-],test
US20110081365A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc([N+](=O)[O-])ccc1Br>>CC(C)(C)OC(=O)Nc1cc([N+](=O)[O-])ccc1Br,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1Cl.OB(O)c1ccc(F)cc1F>>CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1-c1ccc(F)cc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,CCN(C(C)C)C(C)C,,test
US20160046597A1,CCn1cc(C2CCN(C(=O)OC(C)(C)C)CC2)c2cc(NC(=O)c3cc(C#N)ccn3)ccc21>>CCn1cc(C2CCNCC2)c2cc(NC(=O)c3cc(C#N)ccn3)ccc21,,ClCCl,,Cl,O=C([O-])O.[Na+],test
US20070244169A1,c1ccc(COc2ccc3[nH]nc(Nc4nccs4)c3c2)cc1>>Oc1ccc2[nH]nc(Nc3nccs3)c2c1,,CCO,Cl,,,test
US20140057912A1,CC(=O)c1cc(Cl)c(Cl)c(I)c1O.CO>>COc1c(C(C)=O)cc(Cl)c(Cl)c1I,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070179151A1,COc1cc(CC#N)c(C(=O)O)cc1C(=O)N(C)C.Cc1cc(N)n[nH]1>>COc1cc2cc(Nc3cc(C)[nH]n3)nc(O)c2cc1C(=O)N(C)C,,CC(=O)O,,,,test
US05814651,COc1ccc(C2CNC(=O)C2)cc1OC1CCCC1.ClCc1ccc2ccc(Cl)cc2n1>>COc1ccc(C2CC(=O)N(Cc3ccc4ccc(Cl)cc4n3)C2)cc1OC1CCCC1,,CN(C)C=O,O,[H-].[Na+],,test
US20120202792A1,CC(C)(C)OC(=O)NCCCN1CCC(n2cc3c(nc2=O)Nc2cc(CCc4cccc(F)c4)ccc2O3)CC1>>NCCCN1CCC(n2cc3c(nc2=O)Nc2cc(CCc4cccc(F)c4)ccc2O3)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05739345,O=C1SC(Cc2ccc(OCc3nc4cccnc4n3Cc3ccc(-c4ccccc4)cc3)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1>>O=C1NC(=O)C(Cc2ccc(OCc3nc4cccnc4n3Cc3ccc(-c4ccccc4)cc3)cc2)S1,,O,,CC(=O)O,,test
US20060035898A1,CN1CCNCC1.COc1ccccc1-c1n[nH]c2ncc(-c3cccc(C(=O)O)c3)cc12>>COc1ccccc1-c1n[nH]c2ncc(-c3cccc(C(=O)N4CCN(C)CC4)c3)cc12,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04329348,Cl.NCCNC1CCN(CCC2COc3ccccc3O2)CC1.S=C=S>>Cl.S=C1NCCN1C1CCN(CCC2COc3ccccc3O2)CC1,,CCO,,,,test
US20090270351A1,CCOP(=O)(Cc1ccc(C(=O)OC)cn1)OCC>>CCOP(=O)(Cc1ccc(C(=O)O)cn1)OCC,,CO,,C1CCOC1,[Li+].[OH-],test
US20070259860A1,CS(=O)(=O)OCc1cc(-c2cccc(Cl)c2)on1.CSC1=NCCCN1>>CSC1=NCCCN1Cc1cc(-c2cccc(Cl)c2)on1,,CN(C)C=O,,O,[H-].[Na+],test
US20100075973A1,CC[C@@H]1c2c(C#N)ncn2-c2cnc(Cl)nc2N1C1CCCC1.COc1cc(C(=O)O)ccc1N>>CC[C@@H]1c2c(C#N)ncn2-c2cnc(Nc3ccc(C(=O)O)cc3OC)nc2N1C1CCCC1,,C1COCCO1,CCOC(C)=O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040157886A1,Nc1ccccc1.O=C(CCl)N1CCC(Cc2ccccc2)CC1>>O=C(CNc1ccccc1)N1CCC(Cc2ccccc2)CC1,,CCOCC,,,,test
US20070265309A1,CC(C)(C)OC(=O)N1CCC[C@H]1C=O.NCc1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCC[C@@H]1CNCc1ccc(F)cc1,,ClCCCl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04118216,CC1OC(CBr)OC1C.CCCCOC(CN)OCCCC>>CCCCOC(CNCC1OC(C)C(C)O1)OCCCC,,Cc1ccccc1,,CCN(CC)CC,,test
US20150175648A1,Cc1ccc(C(=O)OC[C@H]2O[C@@H](N3C=CC(NC(=O)c4ccccc4)NC3=O)[C@@](F)(Cl)[C@@H]2OC(=O)c2ccc(C)cc2)cc1>>Cc1ccc(C(=O)OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)[C@@](F)(Cl)[C@@H]2OC(=O)c2ccc(C)cc2)cc1,,CC(=O)O,O,,,test
US20110034507A1,COC(=O)c1cccc(Cn2ccc3cc(OCc4c(COc5c(Cl)cccc5Cl)noc4C(C)C)ccc32)c1>>CC(C)c1onc(COc2c(Cl)cccc2Cl)c1COc1ccc2c(ccn2Cc2cccc(C(=O)O)c2)c1,,CO,,C1CCOC1,[Na+].[OH-],test
US20130261116A1,N.O=C(O)c1c(F)cc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)cc1F>>NC(=O)c1c(F)cc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)cc1F,,O=S(Cl)Cl,,,,test
US05686452,CCOC(=O)CP(=O)(OCC)OCC.O=CCC1Cc2ccccc2C1>>CCOC(=O)/C=C/CC1Cc2ccccc2C1,,C1CCOC1,,[H-].[Na+],,test
US20060155121A1,CCCCCC(=O)Cl.Cc1cc(Br)cc(C)c1N>>CCCCCC(=O)Nc1c(C)cc(Br)cc1C,,CC#N,,,,test
US20050187390A1,CC(=O)c1sc(-c2ccccc2)cc1N.O=C(O)c1ccc2c(c1)nc(-c1ccc3nc(-c4cc(Br)ccc4O)ccc3c1)n2C1CCCCC1>>Nc1cc(-c2ccccc2)sc1-c1ccc2cc(-c3nc4cc(C(=O)O)ccc4n3C3CCCCC3)ccc2n1,,CCO,,[K+].[OH-],,test
US20120309739A1,COc1ccc(CN)cc1.N#CCCl>>COc1ccc(CNCC#N)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060148858A1,CCC(CC)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO.COC(=O)Cc1ccnc(C)c1O>>CCC(CC)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCOc1c(CC(=O)O)ccnc1C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US04143055,C=CCc1c(O)cc(C(=O)O)cc1OC>>CC1Cc2c(O)cc(C(=O)O)cc2O1,,CC(=O)O,,Br,,test
US20030045728A1,CC(C)(C)OC(=O)CBr.CCOC(=O)CC(c1ccccc1)c1c[nH]c2cc(O)ccc12>>CCOC(=O)CC(c1ccccc1)c1c[nH]c2cc(OCC(=O)OC(C)(C)C)ccc12,,CC(C)=O,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20160221946A1,COc1ccc(N(C)c2ccc3c(CN(C)C(=O)OC(C)(C)C)cn(S(=O)(=O)c4cccc(C(F)(F)F)c4)c3c2)c(Cl)n1.Cl>>CNCc1cn(S(=O)(=O)c2cccc(C(F)(F)F)c2)c2cc(N(C)c3ccc(OC)nc3Cl)ccc12.Cl,,CO,Cl,,,test
US20120208839A1,CC(C)(C)C(=O)NCc1ccc(Cl)c(Nc2nc3nc(OCC(F)F)c(C(=O)O)cc3[nH]2)c1Cl.NCC1CC1>>CC(C)(C)C(=O)NCc1ccc(Cl)c(Nc2nc3nc(OCC(F)F)c(C(=O)NCC4CC4)cc3[nH]2)c1Cl,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,test
US20120245176A1,CC(C)(C)OC(=O)N1CCNCC1.OCc1cnc(Cl)c(Cl)c1>>CC(C)(C)OC(=O)N1CCN(c2ncc(CO)cc2Cl)CC1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US20090298878A1,CC(C)(C)OC(=O)n1c(CON=C2CCN(S(=O)(=O)c3ccc(OC(F)(F)F)cc3)CC2)nc2ccccc21>>O=S(=O)(c1ccc(OC(F)(F)F)cc1)N1CCC(=NOCc2nc3ccccc3[nH]2)CC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20070105919A1,BrCc1ccccc1.O=C(Nc1nc(-c2ccco2)c(-c2ccncc2)s1)c1cc[nH]c(=O)c1>>O=C(Nc1nc(-c2ccco2)c(-c2ccncc2)s1)c1ccn(Cc2ccccc2)c(=O)c1,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20140243335A1,CC(C)(C)C(=O)N[C@H]1CCc2ccc(C(=O)O)cc2C1.NOC1CCCCO1>>CC(C)(C)C(=O)N[C@H]1CCc2ccc(C(=O)NOC3CCCCO3)cc2C1,,O,,CCN(C(C)C)C(C)C,CN(C)C=O,test
US20150183741A1,CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3c(C=O)cccc3c2)CC1.CCOC(=O)C1CCNCC1>>CCOC(=O)C1CCN(Cc2cccc3cc(O[C@@H]4CC[C@@H](C(C)(C)C)CC4)ccc23)CC1,,ClCCCl,,CC(=O)O,O=C([O-])O.[Na+],test
US20090181928A1,CC(=O)Cl.C[Si](C)(C)CCN1C(=O)CN(c2ccc(/C=C/C3CCCCN3)cc2OCc2ccccc2)S1(=O)=O>>CC(=O)N1CCCCC1/C=C/c1ccc(N2CC(=O)N(CC[Si](C)(C)C)S2(=O)=O)c(OCc2ccccc2)c1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US06313310B1,C#C[Mg]Cl.COc1cc(OC)c(OC)cc1C=O>>C#CC(O)c1cc(OC)c(OC)cc1OC,,C1CCOC1,,,,test
US20150299193A1,O=C1c2ccccc2C(=O)N1OCc1ccc(C(F)(F)F)cc1>>NOCc1ccc(C(F)(F)F)cc1,,CCO,,NN,O,test
US20010021719A1,Cc1c(-c2ccc(OCc3ccccc3)cc2)[nH]c2ccc(OCc3ccccc3)cc12.ClCCCOc1ccc(CBr)cc1>>Cc1c(-c2ccc(OCc3ccccc3)cc2)n(Cc2ccc(OCCCCl)cc2)c2ccc(OCc3ccccc3)cc12,,CN(C)C=O,,O,[H-].[Na+],test
US20020156110A1,CC(C=O)=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1csc(COC(=O)OCC(Cl)(Cl)Cl)n1>>CC(C=O)=Cc1csc(COC(=O)OCC(Cl)(Cl)Cl)n1,,c1ccccc1,,,,test
US20100130474A1,COc1cncc(-c2cc(N)[nH]n2)c1.O=C(O)CCCN1CCCC1.O=C(n1ccnc1)n1ccnc1>>COc1cncc(-c2cc(NC(=O)CCCN3CCCC3)[nH]n2)c1.O=CO,,ClCCCl,,CCN(CC)CC,Cl,test
US20150093655A1,CCCBr.CN(C)CCO>>CCC[N+](C)(C)CCO.[Br-],,CC#N,,Cc1ccccc1,,test
US20110263626A1,CC(N)c1ccc(Oc2ccc(OC(F)F)cc2)cc1.O=C(NC1(C(=O)O)CC1)c1cncnc1>>CC(NC(=O)C1(NC(=O)c2cncnc2)CC1)c1ccc(Oc2ccc(OC(F)F)cc2)cc1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US05744612,Cc1ccc(-c2ccccc2C#N)cc1.[N-]=[N+]=[N-]>>Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US20120010190A1,Cc1cc(/C(C[C@H](c2ccc(CC(=O)O)cc2)c2ccccc2C)=N/O)ccn1.NCCO>>Cc1cc(/C(C[C@H](c2ccc(CC(=O)NCCO)cc2)c2ccccc2C)=N/O)ccn1,,C1CCOC1,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US05550134,CN1C(=O)CC[C@]2(C)c3ccc(S)cc3CC[C@@H]12.O=[N+]([O-])c1ccc2nc(Cl)ccc2c1>>CN1C(=O)CC[C@]2(C)c3ccc(Sc4ccc5cc([N+](=O)[O-])ccc5n4)cc3CC[C@@H]12,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20030018197A1,CCn1nc(C)c(C=O)c1Sc1cc(Cl)cc(Cl)c1>>CCn1nc(C)c(CO)c1Sc1cc(Cl)cc(Cl)c1,,CO,,O,[BH4-].[Na+],test
US20140031374A1,COC(=O)c1ccc(O)cn1.CS(=O)(=O)OCC(F)(F)F>>COC(=O)c1ccc(OCC(F)(F)F)cn1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060069132A1,C#CC(=O)OCC.CC(C)(C)[n+]1cc(=O)o[n-]1>>CCOC(=O)c1ccn(C(C)(C)C)n1,,Cc1ccccc1,,,,test
US04723016,C[Si](C)(C)[O-].O=C(F)C(F)(OC(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F.[K+]>>O=C([O-])C(F)(OC(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F.[K+],,CCOCC,,,,test
US20090096356A1,Cc1ccc(-c2ccc3ccc4cccc5ccc2c3c45)cc1.O=C1CCC(=O)N1Br>>Cc1ccc(-c2ccc3ccc4c(Br)ccc5ccc2c3c54)cc1,,O,,CN(C)C=O,,test
US05750549,Cn1cnnc1C1CCC(N=[N+]=[N-])C1c1ccc(F)cc1>>Cn1cnnc1C1CCC(N)C1c1ccc(F)cc1,[Pd],CO,,,,test
US06809097B1,COC(=O)c1ccc(N)cc1OC.COC=C1C(=O)OC(C)(C)OC1=O>>COC(=O)c1ccc(NC=C2C(=O)OC(C)(C)OC2=O)cc1OC,,CC(C)O,,,,test
US20090270393A1,Cl.N#CC(C(N)=O)C1OC(=O)C(Cl)=C1Cl.NCc1cc(Cl)ccc1S(N)(=O)=O>>Cl.N=c1c(C(N)=O)cc(Cl)cn1Cc1cc(Cl)ccc1S(N)(=O)=O,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20090275537A1,CN(C(=O)NCc1cccc(F)c1Cl)[C@@H](CN)COC(=O)Nc1cc2ccccc2cn1.O=S(=O)(OCC(F)F)C(F)(F)F>>CN(C(=O)NCc1cccc(F)c1Cl)[C@@H](CNCC(F)F)COC(=O)Nc1cc2ccccc2cn1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090030016A1,NC(=O)c1cccc(N)c1N.O=C(O)c1ccc(-c2cnco2)nc1>>NC(=O)c1cccc(NC(=O)c2ccc(-c3cnco3)nc2)c1N,,CN(C)C=O,c1ccncc1,O=C(n1ccnc1)n1ccnc1,,test
US20040185539A1,COC=O.NC[C@@H](O)[C@H](O)[C@H](O)CO>>O=CNC[C@@H](O)[C@H](O)[C@H](O)CO,,CO,,,,test
US20150291549A1,Cc1c(CO)cccc1-c1ccc2c(c1)OCCO2.O=Cc1ccc(O)c(Cl)c1O>>Cc1c(COc2ccc(C=O)c(O)c2Cl)cccc1-c1ccc2c(c1)OCCO2,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020151554A1,CN1CCN(c2ccc(Nc3nc(N)c(C(=O)c4ccc(Cl)c([N+](=O)[O-])c4)s3)cc2)CC1.NCCO>>CN1CCN(c2ccc(Nc3nc(N)c(C(=O)c4ccc(NCCO)c([N+](=O)[O-])c4)s3)cc2)CC1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20160115126A1,CS(=O)(=O)CC#N.Cc1[nH]c2c(C(N)=O)ccc(-c3cccc(C=O)c3)c2c1C>>Cc1[nH]c2c(C(N)=O)ccc(-c3cccc(C=C(C#N)S(C)(=O)=O)c3)c2c1C,,CCO,CCOC(C)=O,C1CCC2=NCCCN2CC1,,test
US20100160308A1,CCOC(OCC)OCC.NC(=O)c1sc(Nc2cc(CN(CCCN3CCOCC3)CCCN3CCOCC3)ccc2[N+](=O)[O-])nc1-c1cccc(Cl)c1>>NC(=O)c1sc(-n2cnc3ccc(CN(CCCN4CCOCC4)CCCN4CCOCC4)cc32)nc1-c1cccc(Cl)c1,[Zn],CC(=O)O,,C1CCOC1,[Cl-].[NH4+],test
US20150051133A1,CC(=CC1CC2CCC1C2)CCC=O>>CC(CCC=O)CC1CC2CCC1C2,[Pd],CCOC(C)=O,,,,test
US20140336224A1,N#CCCC(C(=O)c1ccccc1F)c1ccc(Cl)cc1F.NNCc1ccccc1>>N#CCCC(c1ccc(Cl)cc1F)c1nn(Cc2ccccc2)c2ccccc12,,c1ccncc1,,Cl,Cl,test
US20030149269A1,Cc1csc(C(=C2CCNCC2)c2ccc(F)cc2)c1.O=C(c1cccc(CCl)c1)N1CCCCC1>>Cc1csc(C(=C2CCN(Cc3cccc(C(=O)N4CCCCC4)c3)CC2)c2ccc(F)cc2)c1,,Cc1ccccc1,,CCN(CC)CC,O,test
US05891871,COC(=O)Cc1cc2c(cc1C(=O)c1ccc(OC)cc1)OCO2.NN>>COc1ccc(C2=NNC(=O)Cc3cc4c(cc32)OCO4)cc1,,CCCO,,O,,test
US07078024B2,CC(O)C(=O)O.NCCO>>CC(O)C(=O)O.NCCO,,O,,,,test
US04585768,COc1ccc([C@@H]2Sc3cc(Cl)ccc3N(CCN(C)Cc3ccccc3)C(=O)[C@@H]2OC(C)=O)cc1.O=C(Cl)OCc1ccccc1>>COc1ccc([C@@H]2Sc3cc(Cl)ccc3N(CCN(C)C(=O)OCc3ccccc3)C(=O)[C@@H]2OC(C)=O)cc1,,c1ccccc1,,,,test
US20100216788A1,Cc1cc(N)ccc1Oc1cccc(/C=C/C(C)C)c1.O=C(OCCn1ccc2ncnc(Cl)c21)c1ccccc1>>Cc1cc(Nc2ncnc3ccn(CCO)c23)ccc1Oc1cccc(/C=C/C(C)C)c1,,CC(C)O,,[Na+].[OH-],,test
US20120264789A1,CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1.O=S(=O)(O)O>>CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1.O=S(=O)([O-])[O-],,CCO,,,,test
US20050090501A1,CC(C)(CO)CO.COC(OC)c1cc(-c2ccncc2)n(-c2ccc(F)cc2)n1>>CC1(C)COC(c2cc(-c3ccncc3)n(-c3ccc(F)cc3)n2)OC1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20150239878A1,CN(C(=O)OC(C)(C)C)c1ccc(C=CC=Cc2nc3cc(O)c(O)cc3s2)cc1>>CNc1ccc(C=CC=Cc2nc3cc(O)c(O)cc3s2)cc1,,ClCCl,O,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20110118245A1,CC(C)(c1cc(NC(=O)Oc2ccccc2)n(-c2ccccc2)n1)C(F)(F)F.COc1cc2ncnc(Oc3cccc(N)c3)c2cc1OC>>COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C(F)(F)F)nn4-c4ccccc4)c3)c2cc1OC,CN(C)c1ccncc1,C1CCOC1,,,,test
US05744602,CC(=O)Oc1ccc(-n2c(=O)c3c[nH]c4ccccc4n-3c2=O)cc1>>O=c1c2c[nH]c3ccccc3n-2c(=O)n1-c1ccc(O)cc1,,CCO,,Cl,,test
US20160031903A1,CC(C)(C)OC(=O)NC1CN(c2nc(-c3cc(-c4ccon4)n(Cc4ccccc4F)n3)ncc2F)C1>>NC1CN(c2nc(-c3cc(-c4ccon4)n(Cc4ccccc4F)n3)ncc2F)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050182066A1,CCCc1nn(C)c2c(=O)nc(-c3cc(S(=O)(=O)Cl)ccc3OCC)[nH]c12.CN1CCNCC1>>CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12,,CC(C)=O,,[Na+].[OH-],,test
US20040053941A1,CCO[C@H]1CN(C(=O)OC)C[C@H]1Nc1nc(CC)c(I)nc1CC.COc1cc2c(cc1B(O)O)CCC2>>CCO[C@H]1CN(C(=O)OC)C[C@H]1Nc1nc(CC)c(-c2cc3c(cc2OC)CCC3)nc1CC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20110257191A1,CCOC(=O)c1cnc(Cn2nnc(C(F)(F)F)n2)nc1-c1ccccc1Cl>>O=C(O)c1cnc(Cn2nnc(C(F)(F)F)n2)nc1-c1ccccc1Cl,,CCO,,[Na+].[OH-],,test
US20080312208A1,CCOC(=O)c1cc(C#N)c(Cl)[n+]([O-])c1C.O=C(NS(=O)(=O)Cc1ccccc1)C1CCNCC1>>CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccccc3)CC2)[n+]([O-])c1C,,CCO,,CCN(C(C)C)C(C)C,,test
US20130289067A1,CCOC1CC2C(=O)CCCC2O1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>[N-]=[N+]=N[C@H]1CO[C@@H]2OCC[C@H](O)[C@H]12,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090291079A1,C1CC2CNCC1O2.O=[N+]([O-])c1ccc(-c2nc(Cl)nc(N3[C@@H](CO)CC[C@H]3CO)n2)cc1>>O=[N+]([O-])c1ccc(-c2nc(N3CC4CCC(C3)O4)nc(N3[C@@H](CO)CC[C@H]3CO)n2)cc1,,CCO,,CCN(CC)CC,Cl,test
US20070123581A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)O.O=C(OCc1ccccc1)[C@@H]1C[C@@H]2CCCC[C@@H]2N1>>C[C@H](NC(=O)OC(C)(C)C)C(=O)N1[C@H](C(=O)OCc2ccccc2)C[C@@H]2CCCC[C@@H]21,,CCOC(C)=O,,CCN(CC)CC,Cc1ccc(S(=O)(=O)O)cc1,test
US20120252777A1,COc1ccc(Nc2nc(-c3cccc(C(=O)O)c3)nc3scnc23)cc1OC.On1nnc2ccccc21>>COc1ccc(Nc2nc(-c3cccc(C(N)=O)c3)nc3scnc23)cc1OC,,ClCCl,,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US05334576,CCOC(=O)c1cc(NC(C)=O)c(C)nc1C(=O)OCC.CI>>CCOC(=O)c1cc(N(C)C(C)=O)c(C)nc1C(=O)OCC,,C1CCOC1,,[H-].[Na+],,test
US20060142265A1,CI.Cc1cccc2cc[nH]c12>>Cc1cccc2ccn(C)c12,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US04659516,CCCCNC(=S)CCCCCCCCCC[C@@H]1Cc2cc(OC)ccc2[C@H]2CC[C@@]3(C)[C@@H](CC[C@@H]3O)[C@@H]21>>CCCCNC(=S)CCCCCCCCCC[C@@H]1Cc2cc(O)ccc2[C@H]2CC[C@@]3(C)[C@@H](CC[C@@H]3O)[C@@H]21,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US06630600B1,CCSC(Cc1ccc(O)cc1)C(=O)OC.Cc1ccc(S(=O)(=O)OCCc2ccc(NC(=O)OC(C)(C)C)cc2)cc1>>CCSC(Cc1ccc(OCCc2ccc(NC(=O)OC(C)(C)C)cc2)cc1)C(=O)OC,,CS(C)=O,,[Na+].[OH-],,test
US20120157487A1,CC(C)(C)OC(=O)Nc1nnc(CSc2ccc(Cl)cc2N)[nH]1.O=S(=O)(Cl)c1cc2ccccc2o1>>CC(C)(C)OC(=O)Nc1nnc(CSc2ccc(Cl)cc2NS(=O)(=O)c2cc3ccccc3o2)[nH]1,,c1ccncc1,,,,test
US20110207704A1,CC(C)Oc1ccc(-c2noc(-c3cccc(C(=N)NO)c3)n2)cc1Cl.O=C(n1ccnc1)n1ccnc1>>CC(C)Oc1ccc(-c2noc(-c3cccc(-c4nc(=O)o[nH]4)c3)n2)cc1Cl,,C1COCCO1,O,C1CCC2=NCCCN2CC1,,test
US20100004459A1,CCOC(=O)c1cccnc1-c1cccc(C#N)c1O.Cc1ccccc1CCOS(C)(=O)=O>>CCOC(=O)c1cccnc1-c1ccc(OCCc2ccccc2C)c(C#N)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20120238599A1,C=COCCONC(=O)c1c(Nc2ccc(I)cc2F)n(C)c(=O)c2ccoc12>>Cn1c(Nc2ccc(I)cc2F)c(C(=O)NOCCO)c2occc2c1=O,,CO,ClCCl,Cl,,test
US20060211705A1,CC(C)(C)C(=O)OCc1cccc(Cl)c1NC(=O)c1cnc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)s1>>CC(C)(C)C(=O)OCc1cccc(Cl)c1NC(=O)c1cnc(N)s1,,CCO,,O=CO,,test
US20070078136A1,COc1ccc(CN(c2ccccc2)c2cc(Cl)nn3c(C(N)=O)cnc23)cc1.NC1CCC(N)CC1>>COc1ccc(CN(c2ccccc2)c2cc(N[C@@H]3CC[C@@H](N)CC3)nn3c(C(N)=O)cnc23)cc1,,O,,,,test
US04175130,COC(=O)Cc1nc(-c2ccc(Cl)cc2)oc1Oc1cc(C)ccc1C>>Cc1ccc(C)c(Oc2oc(-c3ccc(Cl)cc3)nc2CC(=O)O)c1,,CC(C)=O,,[Na+].[OH-],,test
US20070191391A1,C=CS(C)(=O)=O.COc1ccc(CN2C(=O)c3c(Cl)ccc(N4CCN([C@H](C)c5ccccc5)CC4)c3C2=O)cc1OC>>COc1ccc(CN2C(=O)c3c(C=CS(C)(=O)=O)ccc(N4CCN([C@H](C)c5ccccc5)CC4)c3C2=O)cc1OC,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,CC(=O)N(C)C,,CC(=O)[O-].[Na+],,test
US20100298324A1,CC(=O)Nc1ccc(CN)cc1.COc1cc(OC)nc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)n1>>COc1cc(OC)nc(-n2c(=S)[nH]c3cc(C(=O)NCc4ccc(NC(C)=O)cc4)ccc3c2=O)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080194629A1,COc1ccc(S(=O)(=O)N[C@@H]2C[C@H](C(=O)NCC3(CCCCO[Si](C)(C)C(C)(C)C)c4ccccc4Oc4ccccc43)CN(C(=O)OCC3c4ccccc4-c4ccccc43)C2)cc1OC>>COc1ccc(S(=O)(=O)N[C@@H]2C[C@H](C(=O)NCC3(CCCCO)c4ccccc4Oc4ccccc43)CN(C(=O)OCC3c4ccccc4-c4ccccc43)C2)cc1OC,,C1COCCO1,,Cl,O=C([O-])O.[Na+],test
US08716484B1,COc1ccc(I)cc1.c1ccc(-c2ccc(Nc3c(-c4ccccc4)cccc3-c3ccccc3)cc2)cc1>>COc1ccc(N(c2ccc(-c3ccccc3)cc2)c2c(-c3ccccc3)cccc2-c2ccccc2)cc1,[Cu],Clc1ccccc1Cl,,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US05821245,CN1CCC(c2cccc3ccc(OS(=O)(=O)C(F)(F)F)cc23)CC1.NCCCc1ccccc1.[C]=O>>CN1CCC(c2cccc3ccc(C(=O)NCCCc4ccccc4)cc23)CC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,,CCN(CC)CC,,test
US20020151535A1,CCNCc1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1>>CCNCc1noc([C@H](CCCC2CCCCC2)CC(=O)O)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090023763A1,CI.COc1ccc(Cn2c(=O)[nH]c3cc(-c4ccncn4)c(-c4ccco4)nc32)c(OC)c1>>COc1ccc(Cn2c(=O)n(C)c3cc(-c4ccncn4)c(-c4ccco4)nc32)c(OC)c1,,CN(C)C=O,,[H][H],[H-].[Na+],test
US20090170907A1,CNC.N#Cc1ccc(N(Cc2ccc(CCl)o2)CC(F)(F)F)cc1C(F)(F)F>>CN(C)Cc1ccc(CN(CC(F)(F)F)c2ccc(C#N)c(C(F)(F)F)c2)o1,,C1CCOC1,,,,test
US20150018343A1,CC(=O)C(F)C(C)=O.CC(C)(C)OC(=O)N1Cc2n[nH]c(N)c2C1>>Cc1nc2c3c(nn2c(C)c1F)CN(C(=O)OC(C)(C)C)C3,,CC(=O)O,,,,test
US20090088431A1,NCC(O)C1CC1.O=C(O)c1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1>>O=C(NCC(O)C1CC1)c1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150087585A1,CCO.N#CC1(n2cc(Cl)cn2)CC1>>CCOC(=N)C1(n2cc(Cl)cn2)CC1,,CCO,,C,C[O-].[Na+],test
US20140200227A1,CC(C)(C)OC(=O)N[C@H]1C[C@@H](C(F)(F)F)CN(c2c(N)cnc3c2CCO3)C1.CC(C)(C)OC(=O)Nc1sc(-c2c(F)cccc2F)nc1C(=O)O>>Nc1sc(-c2c(F)cccc2F)nc1C(=O)Nc1cnc2c(c1N1C[C@H](C(F)(F)F)C[C@H](N)C1)CCO2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130109679A1,CCOC(=O)c1ccc2cc(C(=O)OCC)n([C@H](C)CNC(=O)OC(C)(C)C)c2c1>>CCOC(=O)c1ccc2cc3n(c2c1)[C@H](C)CNC3=O,,CCO,ClCCl,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US05008277,O=C(Cl)C(=O)Cl.O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(OC(c2ccc(Cl)c(Cl)c2)C(F)(F)F)nc1>>O=C1C(=O)N(c2ccc(OC(c3ccc(Cl)c(Cl)c3)C(F)(F)F)nc2)C(=O)N1C(=O)c1c(F)cccc1F,,ClCCCl,,,,test
US20050209195A1,CCOP(=O)(Cl)OCC.COc1cc2c(cc1OC)/C(=C\c1ccc(O)cc1)C(=O)N2>>CCOP(=O)(OCC)Oc1ccc(/C=C2/C(=O)Nc3cc(OC)c(OC)cc32)cc1,,ClCCl,,,,test
US05183921,CC(C)CCON=O.N#CCc1ccccc1Oc1ccccc1>>N#CC(=NO)c1ccccc1Oc1ccccc1,,CCO,,Cl,[Na],test
US20020065309A1,CN(C)c1ccc([C@@H]2C[C@@H]3CNCC34C(=O)N(CCN3CCOCC3)C(=O)N24)c2ccccc12.COc1ccc(C=O)cc1[N+](=O)[O-]>>COc1ccc(CN2C[C@H]3C[C@@H](c4ccc(N(C)C)c5ccccc45)N4C(=O)N(CCN5CCOCC5)C(=O)C34C2)cc1[N+](=O)[O-],,CCOC(C)=O,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20030191118A1,COC(=O)[C@H](Cc1ccc(-c2c(OC)cccc2OC)cc1)NC(=O)c1c(Cl)cccc1Cl.O=[N+]([O-])O>>COC(=O)[C@H](Cc1ccc(-c2c(OC)ccc([N+](=O)[O-])c2OC)cc1)NC(=O)c1c(Cl)cccc1Cl,,C1CCOC1,CCOC(C)=O,,,test
US20060094750A1,CC(C)(C)C(=O)Nc1cc(Cl)ccc1[N+](=O)[O-].CC(C)(C)S>>CC(C)(C)Sc1ccc([N+](=O)[O-])c(NC(=O)C(C)(C)C)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060122065A1,NO.O=Cc1ccc2c(c1)CCC2>>ON=Cc1ccc2c(c1)CCC2,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20090137548A1,COC(=O)c1ccc(-c2ccc(OC)c(-c3ccc(C(F)(F)F)cc3CBr)c2)c(C)c1.C[C@@H]1NC(=O)O[C@@H]1c1cccc(F)c1>>COC(=O)c1ccc(-c2ccc(OC)c(-c3ccc(C(F)(F)F)cc3CN3C(=O)O[C@H](c4cccc(F)c4)[C@@H]3C)c2)c(C)c1,,CC(=O)N(C)C,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20040009995A1,C1CCOC1.Cc1c(Br)cccc1C(=O)O.ClCCl>>Cc1c(Br)cccc1C(=O)OC(C)C,,ClCCl,,O=S(Cl)Cl,,test
US20040152690A1,Fc1cc(-c2cc(C(F)(F)F)cc3[nH]c(Cl)nc23)cc(F)c1F.OCc1cnc(N2CCNCC2)c(C(F)(F)F)c1>>OCc1cnc(N2CCN(c3nc4cc(C(F)(F)F)cc(-c5cc(F)c(F)c(F)c5)c4[nH]3)CC2)c(C(F)(F)F)c1,,CCO,,,,test
US20080090884A1,COC(=O)CP(=O)(OC)OC.O=Cc1ccc(NC(=O)OCc2ccccc2)cc1>>COC(=O)/C=C/c1ccc(NC(=O)OCc2ccccc2)cc1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20110028450A1,C#CCN(CCN(C(=O)C(=O)OCC)C(C)C)C(=O)OC(C)(C)C.Ic1cccs1>>CCOC(=O)C(=O)N(CCN(CC#Cc1cccs1)C(=O)OC(C)(C)C)C(C)C,[Cu]I,Cc1ccccc1,,C1CCNCC1,,test
US20080027036A1,CCO.CCOC(OCC)OCC.O=Cc1ccc(Br)c(F)c1>>CCOC(OCC)c1ccc(Br)c(F)c1,,CCO,,CC(=O)Cl,,test
US06090797,CN1CCC(C(=O)NCCc2ccsc2)CC1>>CN1CCC(C2=NCCc3ccsc32)CC1,,Cc1ccccc1,,,,test
US04717416,O.O=C=NC1CCCCC1.ON=Cc1c(Cl)ccc2cc(Cl)cnc12>>O=C(O)NC1CCCCC1.ON=Cc1c(Cl)ccc2cc(Cl)cnc12,,CN(C)C=O,,,,test
US20160185778A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.O=C(Cl)C1CCC1>>CC(C)(C)OC(=O)N1CCC(=O)C(C(=O)C2CCC2)C1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20080132477A1,CCc1cc(C#N)ncn1>>CCc1cc(CN)ncn1,[Pd],CC(=O)O,,,,test
US20030036612A1,CCC(=O)c1ccccc1.CN(C)C=O.O=P(Cl)(Cl)Cl>>CC(C=O)=C(Cl)c1ccccc1,,O,,CC(=O)[O-].[Na+],,test
US20150018332A1,NCc1cncnc1.O=C(O)/C=C\n1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1>>O=C(/C=C\n1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)NCc1cncnc1,,CO,ClCCl,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20140296136A1,C#CCCC[C@@H]1C[C@H]1OC(=O)ON1C(=O)CCC1=O.N[C@H](C(=O)O)C1CCCCC1>>C#CCCC[C@@H]1C[C@H]1OC(=O)N[C@H](C(=O)O)C1CCCC1,,CC#N,CCOC(C)=O,CCN(CC)CC,O,test
US20040157890A1,O.O=Cc1cc(-c2ccc(C(F)(F)F)cc2)cs1>>O=C(O)c1cc(-c2ccc(C(F)(F)F)cc2)cs1,,CC(C)(C)O,O,CC=C(C)C,[Na+].[O-]Cl,test
US20130211075A1,CCOC(=O)C1CCC2(CC1)OCCO2.Fc1ccc(Br)cn1>>CCOC(=O)C1(c2ccc(Br)cn2)CCC2(CC1)OCCO2,,C1CCOC1,,O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20040006141A1,CC(C)(C)OC(=O)NCCO.CCOC(=O)C(Cc1ccc(O)c([N+](=O)[O-])c1)Oc1ccccc1>>CCOC(=O)C(Cc1ccc(OCCNC(=O)OC(C)(C)C)c([N+](=O)[O-])c1)Oc1ccccc1,,Cc1ccccc1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05091432,CCN(CC)CCNC(=O)c1ccc(N)cc1.Cl.O=C(CCn1cnc2c(=O)[nH]cnc21)Oc1ccc([N+](=O)[O-])cc1>>CCN(CC)CCNC(=O)c1ccc(NC(=O)CCn2cnc3c(=O)[nH]cnc32)cc1.Cl,,CC(C)=O,,CS(C)=O,,test
US20140329798A1,COCc1cnc(N2CCC([C@H]3C[C@@H]3CCOc3cc(F)c(CC(=O)O)c(F)c3)CC2)nc1>>COCc1cnc(N2CCC([C@H]3C[C@@H]3CCOc3cc(F)c(CCO)c(F)c3)CC2)nc1,,C1CCOC1,,CO,,test
US04863920,CN1CC2=C(n3cncc3C1)S(=O)C=C2.II>>CN1CC2=C(n3cnc(I)c3C1)S(=O)C=C2,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US06620940B1,Clc1nsnc1Br.OB(O)c1ccccc1>>Clc1nsnc1-c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,[F-].[K+],,test
US20030055265A1,CC(=O)CC(=O)c1ccc(C(F)(F)F)cc1.CCOC(=O)C(N)Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)c2ccsc12>>CCOC(=O)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)c2ccsc12)N/C(C)=C\C(=O)c1ccc(C(F)(F)F)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20060063805A1,CCNc1cccc(F)c1.O=C1CSC(=S)N1>>CCN(C1=NC(=O)CS1)c1cccc(F)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US05166347,COC(=NC#N)c1cnc2ccccc2c1.NCCc1ccccc1>>N#CNC(=NCCc1ccccc1)c1cnc2ccccc2c1,,CO,,,,test
US20090163592A1,CC(C)(C)C=O.COc1cccc(C(=O)NN)c1C>>COc1cccc(C(=O)NN=CC(C)(C)C)c1C,CC(=O)O,CO,,,,test
US20140128386A1,O=[N+]([O-])c1ncc(Cl)cc1OCc1ncccc1F>>Nc1ncc(Cl)cc1OCc1ncccc1F,[Fe],CCO,,Cl,N,test
US20060111375A1,CCOCC.Cc1ccoc1C.N#Cc1ccccn1>>Cc1cc(C(=O)c2ccccn2)oc1C,,CCCCCC,,Cl,[Li]CCCC,test
US20060167087A1,CCOC(=O)Nc1ccc(C=O)cc1.Nc1ccc(Cl)cc1>>CCOC(=O)Nc1ccc(CNc2ccc(Cl)cc2)cc1,,CCO,,[BH3-]C#N.[Na+],,test
US20150307507A1,CC(C)(C)OC(=O)c1ncc(-c2cnc(C(F)(F)F)nc2)s1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C(O)c1ncc(-c2cnc(C(F)(F)F)nc2)s1,,ClCCl,,,,test
US05292901,CC(=O)CSCCc1ccc2c(c1)OCO2.O=C(OO)c1cccc(Cl)c1>>CC(=O)CS(=O)CCc1ccc2c(c1)OCO2,,ClC(Cl)Cl,,O=C([O-])[O-].[Na+].[Na+],,test
US20130131076A1,CC(=O)c1cncc(Br)c1.OB(O)c1ccccc1>>CC(=O)c1cncc(-c2ccccc2)c1,,CCO,CCOC(C)=O,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(C=O)cnc3Nc3cnc(OC)c(F)c3)n2)cc1.C[Mg]Br>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(C(C)O)cnc3Nc3cnc(OC)c(F)c3)n2)cc1,,C1CCOC1,CCOC(C)=O,O,[Cl-].[NH4+],test
US20110190269A1,COc1cc(Br)ccc1-n1cnc(C)c1.Cc1cc(-c2ccc(F)c(F)c2)c2nc(N)nn2c1>>COc1cc(Nc2nc3c(-c4ccc(F)c(F)c4)cc(C)cn3n2)ccc1-n1cnc(C)c1,,CO,ClCCl,,,test
US20110003787A1,COC[C@H](C)Oc1cc(O[Si](C(C)C)(C(C)C)C(C)C)cc(-c2ccc(C3=NC[C@H](CO[Si](C(C)C)(C(C)C)C(C)C)O3)[nH]2)c1>>COC[C@H](C)Oc1cc(O)cc(-c2ccc(C3=NC[C@H](CO)O3)[nH]2)c1,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20010007875A1,O=C(O)C(Cl)(CCCOc1ccc(F)cc1)C(=O)O>>O=C(O)C(Cl)CCCOc1ccc(F)cc1,,CC(=O)O,Cl,CCOC(C)=O,O,test
US20110311474A1,C[C@@H]1CCNC[C@@H]1c1ncc2cnc3[nH]ccc3n12.O=C(Cl)N1CCCCC1>>C[C@@H]1CCN(C(=O)N2CCCCC2)C[C@@H]1c1ncc2cnc3[nH]ccc3n12,,C1CCOC1,ClCCl,Cl,,test
US20120077814A1,NS(=O)(=O)Cl.O=C(O[C@H]1C[C@H](c2ccc3c(N[C@H]4CCc5ccccc54)ncnn23)CC1CO)c1ccccc1>>NS(=O)(=O)OCC1C[C@@H](c2ccc3c(N[C@H]4CCc5ccccc54)ncnn23)C[C@@H]1OC(=O)c1ccccc1,,CCN(CC)CC,,CC#N,,test
US20070281937A1,CNc1ccc(F)cc1.O=C(O)c1cn(-c2ccc(Cl)cc2)c(Cc2ccc(F)cc2)n1>>CN(C(=O)c1cn(-c2ccc(Cl)cc2)c(Cc2ccc(F)cc2)n1)c1ccc(F)cc1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US05438118,C=CCBr.C[C@@H](N)C(=O)OC(C)(C)C>>C=CCN[C@H](C)C(=O)OC(C)(C)C,,Cc1ccccc1,,CCN(CC)CC,,test
US20140005197A1,COC(=O)C1C2CCC(CC2)C1N.Clc1cncc(Cl)n1>>COC(=O)C1C2CCC(CC2)C1Nc1cncc(Cl)n1,,CC#N,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20130190338A1,COC(=O)c1ccccc1CSc1cc(Cl)ccc1N.O=S(=O)(Cl)c1cc2ccccc2o1>>COC(=O)c1ccccc1CSc1cc(Cl)ccc1NS(=O)(=O)c1cc2ccccc2o1,,c1ccncc1,,,,test
US06780869B1,CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nc(S(C)(=O)=O)n2)cc1.NCC1CCC1>>CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nc(NCC3CCC3)n2)cc1,,CN1CCCC1=O,,O,,test
US20130115310A1,CC(C)(C)OC(=O)N1CCCC(OS(C)(=O)=O)C1.Sc1ccc(Br)cc1>>CC(C)(C)OC(=O)N1CCCC(Sc2ccc(Br)cc2)C1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05866611,C=CCc1cc(C=O)ccc1OCCCNC(C)C.Cl>>C=CCc1cc(C=O)ccc1OCCCNC(C)C.Cl,,CCO,,,,test
US04509972,COc1nc(N)nc2nccnc12.O=C=NS(=O)(=O)OCC(Cl)(Cl)Cl>>COc1nc(NC(=O)NS(=O)(=O)OCC(Cl)(Cl)Cl)nc2nccnc12,,ClCCl,,,,test
US20050239802A1,CCOC(=O)c1cccc(C2=C(c3ccccc3OCc3ccccc3)CCC2)c1>>O=C(O)c1cccc(C2=C(c3ccccc3OCc3ccccc3)CCC2)c1,,CO,,,,test
US20120316161A1,CCCC(C(=O)OCC)c1c(C)nc2c(-c3ccccc3)cnn2c1-c1ccc(C)cc1>>CCCC(C(=O)O)c1c(C)nc2c(-c3ccccc3)cnn2c1-c1ccc(C)cc1,,CCO,,[Na+].[OH-],,test
US20050037925A1,CCSC(C)c1c(C)cc(C)c(C)c1O.COc1cc(Cl)nnc1Cl>>CCSC(C)c1c(C)cc(C)c(C)c1Oc1nnc(Cl)cc1OC,,C1COCCO1,CS(C)=O,O,CC(C)(C)[O-].[K+],test
US20150225354A1,COC(=O)CC1(CC(=O)OC)CC(c2cc(OCc3ccccc3)ccc2/C=C/C(=O)OCc2ccccc2)=NO1>>COC(=O)CC1(CC(=O)OC)CC(c2cc(O)ccc2CCC(=O)O)=NO1,[Pd],C1CCOC1,,,,test
US20070037802A1,O=[N+]([O-])c1c(CS(=O)(=O)c2ccccc2)cccc1OCCCl>>Nc1c(CS(=O)(=O)c2ccccc2)cccc1OCCCl,[Pd],CCO,,NN,O,test
US20020156053A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC[C@@H](F)CO>>CC(C)(C)OC(=O)NC[C@@H](F)CO,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20140275097A1,CC1NCCNC1=O.COc1ccc(C=O)c(OC)c1>>COc1ccc(CN2CCNC(=O)C2C)c(OC)c1,,CC#N,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20060194783A1,CCOC(=O)CCN.O=[N+]([O-])/C=C/c1ccccc1>>CCOC(=O)CCNC(CN)c1ccccc1,[Zn],CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20090118346A1,Cn1cc(C(=O)O)c(C(F)F)n1.Nc1ccc(F)cc1-c1ccc(Cl)c(F)c1>>Cn1cc(C(=O)Nc2ccc(F)cc2-c2ccc(Cl)c(F)c2)c(C(F)F)n1,,ClCCl,O,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20060122215A1,Cc1c2c(n(-c3ccccc3Cl)c1-c1ccc(Cl)cc1)CCNC2=O>>Cc1c2c(n(-c3ccccc3Cl)c1-c1ccc(Cl)cc1)CCNC2,,C1CCOC1,,CO,,test
US20040063775A1,COC(=O)Cc1sc(S)nc1C.Cc1oc(-c2ccccc2)nc1COc1cccc(CCl)c1>>COC(=O)Cc1sc(SCc2cccc(OCc3nc(-c4ccccc4)oc3C)c2)nc1C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150232465A1,CC(=O)N1c2cc(Br)c(-c3ccc(S(C)(=O)=O)cc3)cc2N(C(=O)OC(C)C)C[C@@H]1C.CC(=O)N1c2cc(N)c(-c3cnn(C4CC4)c3)cc2N(C(=O)OC(C)C)C[C@@H]1C>>CC(=O)N1c2cc(C#N)c(-c3cnn(C4CC4)c3)cc2N(C(=O)OC(C)C)C[C@@H]1C,[Cu]Br,,,,,test
US20070049603A1,CC(C)(C)[Si](C)(C)ON=C1CCc2cc(Nc3c(-c4ccccc4C(F)(F)F)oc4cnccc34)ccc21>>ON=C1CCc2cc(Nc3c(-c4ccccc4C(F)(F)F)oc4cnccc34)ccc21,,ClCCl,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04762839,CNC(=O)N1C(=O)C(=O)c2ccccc21.NC(N)=O>>CN1C(=O)Nc2ccccc2C1(O)C(=O)NC(N)=O,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US04364921,COCC(=O)O.Nc1c(I)c(C(=O)Cl)c(I)c(C(=O)Cl)c1I>>COCC(=O)Nc1c(I)c(C(=O)Cl)c(I)c(C(=O)Cl)c1I,,CN(C)C=O,,O=S(Cl)Cl,,test
US04882342,CC(=O)NCC(C)(C)c1ccc2nc(C)[nH]c2c1>>Cc1nc2ccc(C(C)(C)CN)cc2[nH]1,,CCO,,Cl,,test
US09403835B2,CC(=O)OC(C)=O.Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccccc1OC1CCNCC1)C3>>CC(=O)N1CCC(Oc2ccccc2C(=O)N2Cc3nn4c(C)c(Cl)c(C)nc4c3C2)CC1,,ClCCl,,,,test
US20120214803A1,CN(C)c1ccncc1.N#Cc1ccc(S(=O)(=O)Cl)c([N+](=O)[O-])c1.c1ccncc1>>N#Cc1ccc(S(=O)(=O)Nc2cccc3cccnc23)c([N+](=O)[O-])c1,CN(C)c1ccncc1,ClCCl,,,,test
US20040214841A1,Nc1cc(OCc2ccccc2)cc(OCc2ccccc2)c1.O=C(Cl)C(=O)Cl>>O=C1Nc2cc(OCc3ccccc3)cc(OCc3ccccc3)c2C1=O,,CO,,Cl,,test
US20150011546A1,CC(=O)C1COCCO1.COc1ccc(CN)cc1>>COc1ccc(CNC(C)C2COCCO2)cc1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US06057311,O=C(Cl)OCc1ccccc1.c1ccc2c3c([nH]c2c1)CNCC3>>O=C(OCc1ccccc1)N1CCc2c([nH]c3ccccc23)C1,,C1COCCO1,,O=C([O-])O.[Na+],,test
US20030166932A1,CCOC(=O)c1ccc(N(C)c2cc3c(cc2C)C(C)=CCC3(C)C)cc1>>CC1=CCC(C)(C)c2cc(N(C)c3ccc(C(=O)O)cc3)c(C)cc21,,O,,CCO,[K+].[OH-],test
US05770755,BrCCC1c2ccccc2-c2ccccc21.C=Cc1ccc2c(c1)Cc1ccccc1-2>>C=Cc1ccc2c(c1C1(CC)c3ccccc3-c3ccccc31)Cc1ccccc1-2,,CCOCC,,[Li]CCCC,,test
US20060074111A1,CCCCN(Cc1ccc(OCC(=O)OCC)c(C)c1)c1cccc(Br)c1C.Cc1ccc(B(O)O)cc1>>CCCCN(Cc1ccc(OCC(=O)O)c(C)c1)c1cccc(-c2ccc(C)cc2)c1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20120035163A1,CCOC(=O)c1cc2cc(Oc3ccc(S(C)(=O)=O)nc3)cc(CC)c2[nH]1>>CCc1cc(Oc2ccc(S(C)(=O)=O)nc2)cc2cc(C(=O)O)[nH]c12,,C1CCOC1,,CO,[K+].[OH-],test
US05495023,CC(=O)OC(C)=O.CC/C=C(/C=C/CO)CC>>CC/C=C(/C=C/COC(C)=O)CC,,c1ccncc1,,,,test
US20090324581A1,CC(C)Cc1ccc(CO)cc1C(F)(F)F.O=S(Cl)Cl>>CC(C)Cc1ccc(CCl)cc1C(F)(F)F,,ClCCCl,,,,test
US20090281103A1,CCCOC(=O)c1cc(/C=C/COC)nc2ccccc12>>CCCOC(=O)c1cc(CCCOC)nc2ccccc12,,CCOC(C)=O,Cc1ccccc1,,,test
US20130102576A1,CC(C)(C)OC(=O)Nc1ccc2c(c1)C(=O)N(CC(=O)O)C2.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>CC(C)(C)OC(=O)Nc1ccc2c(c1)C(=O)N(CC(=O)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC3CC3)c1)C2,CN(C)c1ccncc1,CN(C)C=O,O,ClCCCl,,test
US20040180912A1,CC(C)O.COc1cc2nc(Cl)nc(-c3ccc(C(C)C)cc3)c2cc1OC>>COc1cc2nc(OC(C)C)nc(-c3ccc(C(C)C)cc3)c2cc1OC,,CC(C)O,CCOC(C)=O,[H-].[Na+],,test
US20160096837A1,CC(C)(C)OC(=O)Nc1cc(N)[nH]n1.COC(=O)c1cccc(N2CCC(=O)C(=CN(C)C)C2)c1>>COC(=O)c1cccc(N2CCc3nc4cc(NC(=O)OC(C)(C)C)nn4cc3C2)c1,,CCO,,,,test
US20060293311A1,COc1c(C)cc([N+](=O)[O-])cc1S(N)(=O)=O>>COc1c(C)cc(N)cc1S(N)(=O)=O,[Fe],CCO,,O,[Cl-].[NH4+],test
US20120225854A1,CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)C[C@@H]2COS(C)(=O)=O)cc1)C(F)(F)F.c1cnc2[nH]ccc2n1>>CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)C[C@@H]2Cn2ccc3nccnc32)cc1)C(F)(F)F,,CC#N,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090076070A1,COC(=O)Cc1ccc(C#N)cc1[N+](=O)[O-]>>N#Cc1ccc2c(c1)NC(=O)C2,[Fe],CC(=O)O,,,,test
US20110142796A1,CC(C)(C)[Si](C)(C)OCCC1CCN(c2ccc(Nc3ncc4c5ccnc(F)c5n(C5CCCC5)c4n3)nc2)CC1>>OCCC1CCN(c2ccc(Nc3ncc4c5ccnc(F)c5n(C5CCCC5)c4n3)nc2)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20070015802A1,COc1ccc(N2CC[C@@H](c3c(OC)cc(OC)c(C(C)=O)c3O)[C@H](OC(C)=O)C2)cc1>>COc1ccc(N2CC[C@@H](c3c(OC)cc(OC)c(C(C)=O)c3O)[C@H](O)C2)cc1,,CO,,[Na+].[OH-],,test
US04146624,Cc1ccc(S(N)(=O)=O)cc1.O=C(O)c1cccc2c1oc1c(C(=O)O)cccc12.c1ccncc1>>N#Cc1cccc2c1oc1c(C#N)cccc12,,O,,ClP(Cl)(Cl)(Cl)Cl,,test
US05380735,C=CCS.Cc1cc(Br)c2nc(Br)sc2c1>>C=CCSc1nc2c(Br)cc(C)cc2s1,,O,,C1CCOC1,[Na+].[OH-],test
US20160068496A1,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.CCCS(=O)(=O)Nc1ccc(F)c(-c2cc(OC)c3nc(Cl)nc(N4CCOCC4)c3c2)c1F>>CCCS(=O)(=O)Nc1ccc(F)c(-c2cc(OC)c3nc(-c4cnc(N)nc4)nc(N4CCOCC4)c3c2)c1F,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20150166480A1,CCOC(=O)c1ccc(-c2cnc(OCC3CCN(CC(C)(C)F)CC3)cn2)cc1F>>CC(C)(F)CN1CCC(COc2cnc(-c3ccc(C(=O)O)c(F)c3)cn2)CC1,,C1CCOC1,O,[Li]O,,test
US20160137636A1,COc1cc(-c2cccc(F)c2)c(Cl)cc1-c1ncnc2cc(S(=O)(=O)Oc3c(F)c(F)c(F)c(F)c3F)ccc12.Nc1cccnn1>>COc1cc(-c2cccc(F)c2)c(Cl)cc1-c1ncnc2cc(S(=O)(=O)Nc3cccnn3)ccc12,,CCOC(C)=O,Cl,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US04894383,CCCCCC1(CCc2ccc(Cl)cc2)CO1.c1nc[nH]n1>>CCCCCC(O)(CCc1ccc(Cl)cc1)Cn1cncn1,,CN1CCCC1=O,,O,[Na+].[OH-],test
US20150166564A1,N#CCN1C[C@@H](N)[C@H](c2ccc(F)c(F)c2)C1.O=C(Nc1c2c(nn1-c1ccccc1)CCC2)Oc1ccccc1>>N#CCN1C[C@@H](NC(=O)Nc2c3c(nn2-c2ccccc2)CCC3)[C@H](c2ccc(F)c(F)c2)C1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,Cl,test
US20160159751A1,Cc1ccc(-c2nc(Cl)c3ccccc3n2)cc1.NCC(c1ccccc1)c1cccc(Cl)n1>>Cc1ccc(-c2nc(NCC(c3ccccc3)c3cccc(Cl)n3)c3ccccc3n2)cc1,,C1CCOC1,O,CCN(C(C)C)C(C)C,,test
US20150031679A1,CC[C@H](C)N.COC(=O)c1ccc2nc(-c3ccccc3)c(Br)nc2c1>>CC[C@@H](C)Nc1nc2cc(C(=O)OC)ccc2nc1-c1ccccc1,,CS(C)=O,,,,test
US20130245065A1,CCNc1ccccc1.COC(=O)CC(=O)Cl>>CCN(C(=O)CC(=O)OC)c1ccccc1,,ClCCl,,,,test
US20050171131A1,CS(=O)(=O)c1ccc(C=O)cc1.Nc1ccc(-c2c(N)nc(N)nc2C2CCCCC2)cc1>>CS(=O)(=O)c1ccc(CNc2ccc(-c3c(N)nc(N)nc3C3CCCCC3)cc2)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20090298865A1,CCOC(=O)c1cc2cccnc2[nH]1.OCc1ccncc1>>CCOC(=O)c1cc2cccnc2n1Cc1ccncc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100113539A1,CC(C)(C)OC(=O)NCCOc1cccc(N)c1.CCCC(C)S(=O)(=O)Cl>>CCCC(C)S(=O)(=O)Nc1cccc(OCCNC(=O)OC(C)(C)C)c1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20070185165A1,O=c1onc(-c2nonc2CO)n1-c1ccc(F)c(Cl)c1.Oc1ccccc1>>O=c1onc(-c2nonc2COc2ccccc2)n1-c1ccc(F)c(Cl)c1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060004052A1,C#CCBr.C#CCN1CCCC1.C1CCNC1.C1CCOC1.CCN(CC)CC.COC(=O)c1[nH]c2cc(NC(=O)OC(C)(C)C)cc3c2c1C=NNC3=O>>C#CCN1CCCC1.O=C1NN=Cc2c(C#CCN3CCCC3)[nH]c3cc(NC(=O)[C@@H]4C[C@H]4c4ccccc4)cc1c23,,CCN(CC)CC,,,,test
US20070043065A1,CCOC(OCC)OCC.Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1cc(N2CCCN(C)CC2)ccc1N>>Cc1ccc(C(=O)NC2CC2)cc1-n1cnc2ccc(N3CCCN(C)CC3)cc2c1=O,,CCO,,CC(=O)O,,test
US20050209284A1,CN(C(=O)c1ccccc1)c1ccc(NCCc2cccnc2)c(N)c1.CSC(=NNC(=O)OCc1ccccc1)NNC(=O)OCc1ccccc1>>CN(C(=O)c1ccccc1)c1ccc2c(c1)nc(NC(=O)OCc1ccccc1)n2CCc1cccnc1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100168080A1,COc1cc(O)c([N+](=O)[O-])cc1Cl.OCCBr>>COc1cc(OCCBr)c([N+](=O)[O-])cc1Cl,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05529997,COC(=O)[C@H](CCCC=O)NC(=O)C(Cc1ccccc1)N1C(=O)c2ccccc2C1=O>>COC(=O)C1CCC=CN1C(=O)C(Cc1ccccc1)N1C(=O)c2ccccc2C1=O,,ClCCl,O,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20130317026A1,CNC.Cc1cc(C)c(CNC(=O)c2cc(-c3cccc(CBr)c3)nc3c2cnn3C(C)C)c(=O)[nH]1>>Cc1cc(C)c(CNC(=O)c2cc(-c3cccc(CN(C)C)c3)nc3c2cnn3C(C)C)c(=O)[nH]1,,CCOC(C)=O,,CN(C)C=O,O,test
US06277849B1,COc1cc(C=C[N+](=O)[O-])ccc1OCc1cccc2ccccc12>>COc1cc(CCN)ccc1OCc1cccc2ccccc12,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US05502187,Clc1cc(Cl)nc(Cl)n1.NCCS(=O)(=O)O>>O=S(=O)(O)CCNc1cc(Cl)nc(Cl)n1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US05922751,CCOC(=O)CC(C)=O.COc1ccc(C=O)cc1OC1CCCC1>>CCOC(=O)C(=Cc1ccc(OC)c(OC2CCCC2)c1)C(C)=O,,Cc1ccccc1,O,C1CCNCC1,CC(=O)O,test
US20110086834A1,CN(C)C=O.COC(C)(OC)c1nccs1>>COC(C)(OC)c1ncc(C=O)s1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20120035161A1,CC(C)(C)OC(=O)NC(C)(C)C(=O)NCCN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1>>CC(C)(N)C(=O)NCCN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060089404A1,C1CCOC1.C[Mg]Cl.O=c1cc(C(F)(F)F)c2cc(Cl)c(O)cc2o1>>CC1(C)C=C(C(F)(F)F)c2cc(Cl)c(O)cc2O1,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,O,,test
US05075303,Cc1ccnc2c1CCCC2.O=C(OO)c1cccc(Cl)c1>>Cc1cc[n+]([O-])c2c1CCCC2,,ClCCl,,,,test
US05605905,CCc1cc2c(OC)ccc(OC)c2nc1Cl.O>>CCc1cc2c(OC)ccc(OC)c2[nH]c1=O,,O,,CC(=O)O,,test
US20140148433A1,COC(=O)Cl.Nc1nc(-c2nn(Cc3ccccc3F)c3ncc(F)cc23)nc(N)c1N>>COC(=O)Nc1c(N)nc(-c2nn(Cc3ccccc3F)c3ncc(F)cc23)nc1N,,ClCCl,c1ccncc1,,,test
US20080293718A1,CN1C(=O)C(c2ccc(OS(C)(=O)=O)cc2)(c2cccc(Br)c2)NC1N.OB(O)c1cccnc1>>CN1C(=O)C(c2ccc(OS(C)(=O)=O)cc2)(c2cccc(-c3cccnc3)c2)N=C1N,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20030171359A1,CC(C)Oc1cnc(S)nc1O.O=C(O)CCl>>CC(C)Oc1c[nH]c(=O)[nH]c1=O,,O,,Cl,,test
US06458337B1,CO.Cl.N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O>>COC(=O)[C@@H](N)Cc1c[nH]c2ccccc12.Cl,,CO,,CCOCC,,test
US20140200227A1,CC(=O)OC1CCc2c1ncc(N)c2N1C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](C)C1.COc1ccc(F)c(-c2nc(C(=O)O)ccc2F)c1F>>COc1ccc(F)c(-c2nc(C(=O)Nc3cnc4c(c3N3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](C)C3)CCC4OC(C)=O)ccc2F)c1F,,CN(C)C=O,CO,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070117798A1,CC(=O)CCl.COC(=O)c1ccc(NC=O)c(OC)c1>>COC(=O)c1ccc(N(C=O)CC(C)=O)c(OC)c1,,CCOC(C)=O,CN(C)C=O,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US20020161010A1,Clc1nc(-c2ccccc2)nc2ccccc12.Nc1ccncc1>>c1ccc(-c2nc(Nc3ccncc3)c3ccccc3n2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030152520A1,CCC(=O)Cl.COc1cc(OC(F)(F)F)ccc1-c1nc(OC)c(N)cc1C>>CCC(=O)Nc1cc(C)c(-c2ccc(OC(F)(F)F)cc2OC)nc1OC,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20100317645A1,CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3ccc(C#N)cc32)cc1.[N-]=[N+]=[N-]>>CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3ccc(-c4nn[nH]n4)cc32)cc1,,CCOC(C)=O,CN(C)C=O,[Cl-].[NH4+],,test
US20150148342A1,Cc1ccc(S(=O)(=O)n2ccc3c(-c4ccc(N)c([N+](=O)[O-])c4Oc4ccc(F)cc4F)cn(C)c(=O)c32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(-c4ccc(N)c(N)c4Oc4ccc(F)cc4F)cn(C)c(=O)c32)cc1,[Zn],CCOC(C)=O,,CO,[Cl-].[NH4+],test
US05095015,O=C(Cl)OCc1ccccc1.O=c1[nH]c2c(c3nc(-c4ccccc4F)cn13)CNCC2>>O=C(OCc1ccccc1)N1CCc2[nH]c(=O)n3cc(-c4ccccc4F)nc3c2C1,,CN(C)C=O,,CCN(CC)CC,,test
US20100179122A1,NCc1cccc(F)c1.O=C(O)c1[nH]c2ccc(Br)cc2c1S(=O)(=O)N1CCCC1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>NC(=O)N(Cc1cccc(F)c1)c1[nH]c2ccc(Br)cc2c1S(=O)(=O)N1CCCC1,,c1ccccc1,,CCN(CC)CC,,test
US04239760,CC(=O)CC(C)=O.NNc1nc2ccc(Cl)cc2[n+]([O-])n1>>Cc1cc(C)n(-c2nc3ccc(Cl)cc3[n+]([O-])n2)n1,,CCO,,,,test
US20150291573A1,CI.O=S(=O)(c1cccc(C(F)(F)F)c1)C1CCC(c2ccc(Cl)cc2)OC1>>CC1(S(=O)(=O)c2cccc(C(F)(F)F)c2)CCC(c2ccc(Cl)cc2)OC1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20140371283A1,Cc1cc(C=O)ccc1OC(F)F.Clc1cccc(C2SCCCS2)c1>>Cc1cc(C(O)C2(c3cccc(Cl)c3)SCCCS2)ccc1OC(F)F,,C1CCOC1,,[Li]CCCC,,test
US05977134,O=C1NCCc2cc(Br)ccc21>>Brc1ccc2c(c1)CCNC2,,C1CCOC1,,CO,,test
US06232290B1,C=CCBr.COC(=O)c1ccc(-c2ccc(O)cc2)cc1>>C=CCOc1ccc(-c2ccc(C(=O)OC)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04404137,CCOC(=O)c1cn(C)nc1N.O=[N+]([O-])c1cc(F)ccc1F>>CCOC(=O)c1cn(C)nc1Nc1ccc(F)cc1[N+](=O)[O-],,C1CCOC1,,Cl,[Li]CCCC,test
US20140005183A1,C[Si](C)(C)CCOCn1cc(-c2cccc(C#N)c2)c2c(N3CCOCC3)ncnc21.NO>>C[Si](C)(C)CCOCn1cc(-c2cccc(C(N)=NO)c2)c2c(N3CCOCC3)ncnc21,,CCO,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20110039895A1,COC(=O)c1c(OC)ccc2c1ncn2Cc1ccccc1>>COc1ccc2c(ncn2Cc2ccccc2)c1C(=O)O,,CO,,Cl,[Na+].[OH-],test
US20060122399A1,CO.N#Cc1cccc(F)c1>>COC(=N)c1cccc(F)c1,,CO,,CO[Na],,test
US20040044029A1,O=C1CC[C@H]2CCN(C(=O)OCc3ccccc3)C[C@H]12>>O=C1CC[C@H]2CCN(C(=O)OCc3ccccc3)C[C@@H]12,,CCN(CC)CC,,,,test
US20140329799A1,Sc1nc2cccc(Cl)c2s1>>Clc1cccc2ncsc12,[Fe],CC(=O)O,,,,test
US06740647B1,BrC(Br)(Br)Br.N#Cc1csc(CO)c1Cl>>N#Cc1csc(CBr)c1Cl,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20120220622A1,COC(C)(OC)N(C)C.O=C1CN(Cc2ccc(Br)cn2)C(=O)N1>>CN1C(=O)CN(Cc2ccc(Br)cn2)C1=O,,Cc1ccccc1,,,,test
US20150368240A1,COC(=O)c1cccc(O)c1.C[Si](C)(C)C#CCBr>>COC(=O)c1cccc(OCC#C[Si](C)(C)C)c1,,CN(C)C=O,,[H-].[Na+],,test
US20130303497A1,C1=CCC=C1.O=C(O)C#CC(=O)O>>O=C(O)C1=C(C(=O)O)C2C=CC1C2,,CCOCC,,,,test
US03932407,CCNCC(=O)O.O=[N+]([O-])c1ccccc1CCl>>O=C(O)CNCCCc1ccccc1[N+](=O)[O-],,CCO,,CCN(CC)CC,Cl,test
US20050101636A1,CCOC(=O)C(Br)CC.O=Cc1cccc(O)c1>>CCOC(=O)C(CC)Oc1cccc(C=O)c1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20130158006A1,Cc1c(O)cccc1C(=O)O.O=[N+]([O-])O>>Cc1c(C(=O)O)ccc([N+](=O)[O-])c1O,,O=S(=O)(O)O,,,,test
US20090247524A1,N#CCBr.Nc1nc(SCc2ccccc2)nc(-c2cc(O)c(Cl)cc2Cl)n1>>N#CCOc1cc(-c2nc(N)nc(SCc3ccccc3)n2)c(Cl)cc1Cl,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070265331A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(F)c(F)c1)C(=O)CBr>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(F)c(F)c1)[C@H]1CO1,,C1CCOC1,CCO,[BH4-].[Na+],,test
US04680296,O=c1[nH]c2ccccc2n1CCBr.OC(c1ccccc1)(c1ccccc1)C1CCNCC1>>O=c1[nH]c2ccccc2n1CCN1CCC(C(O)(c2ccccc2)c2ccccc2)CC1,,CC(=O)CC(C)C,,[I-].[Na+],,test
US20140100231A1,COc1ccc(Cn2nc(CO)cc(OC)c2=O)cc1.CS(=O)(=O)Cl>>COc1ccc(Cn2nc(CCl)cc(OC)c2=O)cc1,,ClCCl,ClCCl,CCN(C(C)C)C(C)C,,test
US20140100229A1,COC(=O)C(C)(C)c1nnc(-c2nn(CC3CCCC3)c3ncc(F)cc23)nc1O.N>>CC1(C)C(=O)Nc2nc(-c3nn(CC4CCCC4)c4ncc(F)cc34)nnc21,,CC#N,,O=P(Cl)(Cl)Cl,,test
US20140275152A1,CC(=O)OC(C)=O.OCC1=C(c2ccccc2)CCNC1>>CC(=O)N1CCC(c2ccccc2)=C(CO)C1,,ClCCl,O,CCN(C(C)C)C(C)C,Cl,test
US20080139631A1,BrCC1CC1.CCOC(=O)c1cc2cc([N+](=O)[O-])ccc2[nH]1>>CCOC(=O)c1cc2cc([N+](=O)[O-])ccc2n1CC1CC1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160122331A1,COC(=O)c1ccc([C@H]2C[C@H](NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)C[C@@H](c3ccc(OC)cc3)O2)cc1>>COc1ccc([C@@H]2C[C@@H](NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)C[C@H](c3ccc(C(=O)O)cc3)O2)cc1,,CO,,[Li+].[OH-],,test
US20130158009A1,CC(C)(C)OC(=O)NC1CCNCC1.CCc1cnc(Cl)nc1>>CCc1cnc(N2CCC(NC(=O)OC(C)(C)C)CC2)nc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20140179689A1,Cl.Clc1ccnc(Cl)n1.c1ccc2c(c1)CCN2>>Cl.Clc1nccc(N2CCc3ccccc32)n1,,Cl,,,,test
US20150038488A1,CC(C)C(=O)O.C[C@@H](Oc1nc(-c2ccc(N3CCNCC3)cc2)cc2ncn(C)c12)[C@H]1CNC(=O)C1>>CC(C)C(=O)N1CCN(c2ccc(-c3cc4ncn(C)c4c(O[C@H](C)[C@H]4CNC(=O)C4)n3)cc2)CC1,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080085890A1,CC(=O)Nc1ccc(CCCN(C)C)cc1.Cl>>CN(C)CCCc1ccc(N)cc1.Cl,Cl,CO,,,,test
US20030087775A1,CC(=O)OC(C)=O.CC(C)(O)CCC1CCCC1>>CC(=O)OC(C)(C)CCC1CCCC1,,O,,O=P(O)(O)O,,test
US20100076029A1,CC(C)(CO)c1cc(NC(=O)C(C)(C)S(=O)(=O)C2CCOCC2)on1>>CC(C)(C=O)c1cc(NC(=O)C(C)(C)S(=O)(=O)C2CCOCC2)on1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20080318947A1,COc1ccc(CCl)cc1.O=Cc1cccc(O)c1>>O=Cc1cccc(OCc2ccccc2)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05403842,Cc1c(-c2ccccc2)oc2c(N)cccc2c1=O.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>Cc1c(-c2ccccc2)oc2c(NC(=O)C(F)(F)F)cccc2c1=O,,ClCCl,,,,test
US20050240021A1,COc1cc(C(=O)CBr)ccc1-c1ccccn1.NC1=NCCS1>>COc1cc(-c2cn3c(n2)SCC3)ccc1-c1ccccn1,,CCO,,,,test
US20150166564A1,CC1(C)CO1.Nc1cc(=O)[nH]n1-c1ccccc1>>CC(C)(O)COc1cc(N)n(-c2ccccc2)n1,,CC(=O)N(C)C,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20080194696A1,C=CC[Mg]Br.Cc1ccc(C#CC=O)cc1>>C=CCC(O)C#Cc1ccc(C)cc1,,C1CCOC1,,,,test
US04373104,CC(C)CO.COc1cc2c(cc1OC)C(C(S)(C#N)CCC(=O)O)=NCC2>>CCC(C)OC(=O)CCC(S)(C#N)C1=NCCc2cc(OC)c(OC)cc21,,CC(C)CO,,,,test
US20110230517A1,COC(=O)c1ccc(=O)n(-c2ccc(F)cc2)c1>>O=C(O)c1ccc(=O)n(-c2ccc(F)cc2)c1,,CCO,,[Na+].[OH-],,test
US20020137766A1,CN(C(=O)OC(C)(C)C)C1C2CCC1CNC2.Cc1ccc(S(=O)(=O)OCCCNc2ccc(C#N)cc2)cc1>>CN(C(=O)OC(C)(C)C)C1C2CCC1CN(CCCNc1ccc(C#N)cc1)C2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020022631A1,CCO.O=C(O)CNc1cccc([N+](=O)[O-])c1>>CCOC(=O)CNc1cccc([N+](=O)[O-])c1,,O,,,,test
US20090264440A1,COCCN.Cn1c(C=O)cnc1-c1cc2nccc(Oc3ccc([N+](=O)[O-])cc3F)c2s1>>COCCNCc1cnc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)n1C,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20080023671A1,Cc1ccccc1S(=O)(=O)n1cccc1C(=O)c1cc(NC(=O)C(F)(F)F)cc(NC(=O)C(F)(F)F)c1>>Nc1cc(N)cc(C(=O)c2ccc[nH]2)c1,,CCO,,[K+].[OH-],,test
US20110076291A1,C=CS(=O)(=O)N1CC(c2ccc3c(c2)OCCc2sc(-c4ncnn4C(C)C)nc2-3)C1.FC1(F)CNC1>>C=CS(=O)(=O)N1CC(F)(F)C1,,ClCCl,,Cl,,test
US20030065189A1,C#CC(CF)C(F)OS(=O)(=O)c1ccc(C)cc1.Oc1ccc(C(F)(F)F)cc1>>C#CC(CF)(CF)Oc1ccc(C(F)(F)F)cc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20070149561A1,CS(=O)(=O)Cl.[O-][n+]1ccc(Br)c2cc[nH]c21>>Clc1cc(Br)c2cc[nH]c2n1,,CN(C)C=O,,,,test
US20130253194A1,CC(C)(C)OC(=O)N1CCNCC1.Clc1ccn2ncc(Br)c2n1>>CC(C)(C)OC(=O)N1CCN(c2ccn3ncc(Br)c3n2)CC1,,CC(C)O,O,CCN(C(C)C)C(C)C,,test
US20150225412A1,CC(C)(C)C=C(C#N)C(=O)O.N#CCC(=O)N1CCC[C@@H]1Cn1c(NC(=O)c2ccc(C(F)F)s2)nc2ccccc21>>CC(C)(C)C=C(C#N)C(=O)N1CCC[C@@H]1Cn1c(NC(=O)c2ccc(C(F)F)s2)nc2ccccc21,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090192156A1,COC1CCNCC1.O=C(O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F>>COC1CCN(C(=O)c2cccc(Cc3n[nH]c(=O)c4ccccc34)c2)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US05216167,CCOc1cc(CC(=O)NC(c2ccccc2)c2ccccc2N2CCCCC2)ccc1CCl.[C-]#N>>CCOc1cc(CC(=O)NC(c2ccccc2)c2ccccc2N2CCCCC2)ccc1CC#N,,CS(C)=O,,O,,test
US04988703,O=C(NC1C(COC(=O)c2ccccc2)C1COC(=O)c1ccccc1)OCc1ccccc1>>O=C(NC1C(CO)C1CO)OCc1ccccc1,,CO,,C[O-].[Na+],,test
US20100160297A1,COc1cccc2cc[n+]([O-])cc12.O=P(Cl)(Cl)Cl>>COc1cccc2ccnc(Cl)c12,,O=P(Cl)(Cl)Cl,,Cl,,test
US20070203159A1,COc1ccc(CCl)cc1.Nc1nc(Cl)c2nc[nH]c2n1>>COc1ccc(Cn2cnc3c(Cl)nc(N)nc32)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100160327A1,Nc1ccccc1N.O=C(O)c1ccc(C(C(=O)Nc2ccccc2)C(=O)Nc2ccccc2)nc1>>Nc1ccccc1NC(=O)c1ccc(C(C(=O)Nc2ccccc2)C(=O)Nc2ccccc2)nc1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US05223508,CC(C)OC(=NC#N)c1cccnc1.NCCc1ccc(N)cc1>>N#CNC(=NCCc1ccc(N)cc1)c1cccnc1,,CO,,,,test
US20080038242A1,CC(=O)OC[C@H]1O[C@@H](n2c(N)nc3ccccc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O.O=Cc1ccc(-n2ccnc2)cc1>>OC[C@H]1O[C@@H](n2c(NCc3ccc(-n4ccnc4)cc3)nc3ccccc32)[C@H](O)[C@@H]1O,,C1CCOC1,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090221663A1,COC(=O)c1ccc(N(N)C(=O)OC(C)(C)C)cc1OC.Cl>>COC(=O)c1ccc(NN)cc1OC.Cl,,C1COCCO1,,,,test
US20130211075A1,Cc1c(C(=O)Nc2ccc(C3=CCN(C(=O)OC(C)(C)C)CC3)nc2)cnn1-c1ccc(C(F)(F)F)cn1>>Cc1c(C(=O)Nc2ccc(C3=CCNCC3)nc2)cnn1-c1ccc(C(F)(F)F)cn1,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20060009453A1,N=C1OCCN1Cc1ccc(C(F)(F)F)cc1[N+](=O)[O-]>>N=C1OCCN1Cc1ccc(C(F)(F)F)cc1N,[Pd],CO,,[H][H],,test
US20140378461A1,CC(C)(C)OC(=O)N[C@@H]1C[C@]1(C)c1ccc(Cl)cc1.Cl>>CC1(c2ccc(Cl)cc2)CC1N.Cl,,ClCCl,,,,test
US20030064991A1,CS(=O)(=O)Cl.O=C(OCc1ccccc1)c1c(C(F)(F)F)[nH]c2ccc(CCO)cc12>>CS(=O)(=O)OCCc1ccc2[nH]c(C(F)(F)F)c(C(=O)OCc3ccccc3)c2c1,,C1CCOC1,,CCN(CC)CC,,test
US05530019,CCCCCC/C=C/C(=O)OCC>>CCCCCC/C=C/C(=O)O,,C1COCCO1,CCO,[Na+].[OH-],,test
US07781483B2,COc1cc2c(cc1[N+](=O)[O-])OC(C)(C)[C@@H]1O[C@H]21.N>>COc1cc2c(cc1[N+](=O)[O-])OC(C)(C)[C@H](O)[C@H]2N,,CCO,,O,,test
US20040157904A1,CC(C)I.COc1ccc(Nc2ccnn2-c2ccccc2)c(C(=O)O)c1>>COc1ccc(Nc2ccnn2-c2ccccc2)c(C(=O)OC(C)C)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090105252A1,C1COCCN1.CC(Cl)c1ccc(Br)cc1>>CC(c1ccc(Br)cc1)N1CCOCC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20100144727A1,CCI.COC(=O)C1COC(=O)N1>>CCN1C(=O)OCC1C(=O)OC,,CN(C)C=O,,[H-].[Na+],,test
US20120052046A1,CCCOC(=O)[C@@H](N)c1ccccc1.O=P(Cl)(Cl)Oc1cccc2ccccc12>>CCCOC(=O)[C@@H](N=[P+]([O-])Oc1c(Cl)ccc2ccccc12)c1ccccc1,,ClCCl,,Cl,,test
US05919969,CCCCCCCCCCCCOC(=O)c1ccc(Cl)c(N)c1.CCOC(=O)C(C(=O)OCC)N1C(=O)c2ccccc2C1=O>>CCCCCCCCCCCCOC(=O)c1ccc(Cl)c(NC(=O)C(C(=O)OCC)N2C(=O)c3ccccc3C2=O)c1,,Cc1ccccc1,,,,test
US20120083475A1,CC(N)c1ccccc1.CC1(C)OC(=O)C2(CC2)C(=O)O1>>CC(c1ccccc1)N1CCC(C(=O)O)C1=O,,CCO,,,,test
US20110130409A1,CCOC(=O)CC1CCc2c1[nH]c1ccc(OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)cc21>>O=C(O)CC1CCc2c1[nH]c1ccc(OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)cc21,,C1COCCO1,,Cl,[Li+].[OH-],test
US05510504,Br.CCOP(=O)(C(Cc1ccccc1)N=C(c1ccccc1)c1ccccc1)C(Cc1ccccc1)N=C(c1ccccc1)c1ccccc1>>Br.NC(Cc1ccccc1)P(=O)(O)C(N)Cc1ccccc1,,CC(=O)O,,,,test
US20150225397A1,CC1C2CCc3c(n[nH]c3-c3ccccc3)C2(c2ccccc2)CCC12OCCO2>>CC1C(=O)CCC2(c3ccccc3)c3n[nH]c(-c4ccccc4)c3CCC12,,CO,,Cl,,test
US04066651,CCOC(=O)C(C(=O)OCC)c1cc(=O)n(-c2ccccc2)c2ccccc12>>O=C(O)Cc1cc(=O)n(-c2ccccc2)c2ccccc12,,CCO,O,[Na+].[OH-],,test
US20070254931A1,CC(=O)Nc1nc(CCCc2ccc(C=O)cc2)cs1.CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)/C=C/c1ccc(CCCc2csc(NC(C)=O)n2)cc1,,ClC(Cl)Cl,,,,test
US04711889,Br.O=C(NCCn1c2ccccc2c(=O)c2ccccc21)OCc1ccccc1>>Br.NCCn1c2ccccc2c(=O)c2ccccc21,,CC(=O)O,,,,test
US20100094000A1,CN(C)/C=C/C(=O)c1ccc(F)cc1F.CNN>>Cn1nccc1-c1ccc(F)cc1F,,CC(C)O,,CCN(CC)CC,,test
US20060287291A1,C[C@@H]1CN(C(=O)OC(C)(C)C)[C@@H](C)CN1Cc1cc(N)cc2ccoc12.Cc1ccccc1S(=O)(=O)Cl>>Cc1ccccc1S(=O)(=O)Nc1cc(CN2C[C@H](C)N(C(=O)OC(C)(C)C)C[C@H]2C)c2occc2c1,,CC#N,,,,test
US20120178162A1,CCO[Si](CCCN)(OCC)OCC.CO[Si](OC)(OC)OC>>CCO[Si](CCCN)(OCC)OCC.CO[Si](OC)(OC)OC,,O,,,,test
US20140080825A1,COC(=O)C1(C#Cc2ccc(OC)cc2)CC1>>COc1ccc(C#CC2(C(=O)O)CC2)cc1,,C1CCOC1,,O,[Li+].[OH-],test
US20140031349A1,CCOC(=O)C(C)(C)N1CCC2(CCNC2=O)CC1>>CC(C)(C=O)N1CCC2(CCNC2=O)CC1,,Cc1ccccc1,,CC(C)C[AlH]CC(C)C,,test
US20080300290A1,CCOC(=O)C(C)(C)Oc1ccc(-c2cn(CCC(C)(C)NC(=O)OC(C)(C)C)cn2)cc1>>CCOC(=O)C(C)(C)Oc1ccc(-c2cn(CCC(C)(C)N)cn2)cc1,,Cl,,,,test
US20050187230A1,CSc1ncc2cc(-c3c(Cl)ccc(NC(=O)c4cccc(C(F)(F)F)c4)c3Cl)c(N)nc2n1.O=C(O)C(F)(F)F>>CSc1ncc2cc(-c3c(Cl)ccc(NC(=O)c4cccc(C(F)(F)F)c4)c3Cl)c(=O)[nH]c2n1,,O=C(O)C(F)(F)F,,O=N[O-].[Na+],,test
US20070135467A1,N[C@@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(N[C@@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1)Oc1ccc([N+](=O)[O-])cc1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US03954764,COc1ccc2c(c1)Sc1ccc(SC)cc1C(N1CCNCC1)C2.O=C1CCCN1CCCl>>COc1ccc2c(c1)Sc1ccc(SC)cc1C(N1CCN(CCN3CCCC3=O)CC1)C2,,Cc1ccccc1,,[I-].[K+],O=C([O-])O.[Na+],test
US20090143444A1,CN(Cc1cc(Br)n(S(=O)(=O)c2cccnc2)c1)C(=O)OC(C)(C)C.CS(=O)(=O)c1ccc(B(O)O)cc1>>CN(Cc1cc(-c2ccc(S(C)(=O)=O)cc2)n(S(=O)(=O)c2cccnc2)c1)C(=O)OC(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20150065519A1,CS(=O)(=O)Cl.Nc1cc(-c2ncc(-c3ccc(NS(=O)(=O)C(F)(F)F)cc3Cl)s2)ccn1>>CS(=O)(=O)Nc1cc(-c2ncc(-c3ccc(NS(=O)(=O)C(F)(F)F)cc3Cl)s2)ccn1,,c1ccncc1,,,,test
US20110263556A1,CC1CCNCC1.O=C(O)c1cc([N+](=O)[O-])ccc1Cl>>CC1CCN(c2ccc([N+](=O)[O-])cc2C(=O)O)CC1,,Cl,,,,test
US20130245042A1,Clc1c(NC[C@@H]2CCC[C@H]2c2ccccc2)ccn2c(CC3CC3)nnc12>>Clc1c(NC[C@H]2CCC[C@@H]2c2ccccc2)ccn2c(CC3CC3)nnc12,,CCO,,,,test
US20120277224A1,COC(=O)CC(=O)c1ccccc1.Nc1[nH]ncc1-c1ccccn1>>O=c1cc(-c2ccccc2)[nH]c2c(-c3ccccn3)cnn12,,CC(=O)O,,,,test
US20060183762A1,CC(C)(C)OC(=O)NC1CCNC1.CCOC(=O)c1ccc(F)c(F)c1F>>CCOC(=O)c1ccc(N2CCC(NC(=O)OC(C)(C)C)C2)c(F)c1F,,CC#N,,CCN(CC)CC,,test
US05162328,CC(O)C(=O)O.c1cc(Nc2nccc(-c3cccs3)n2)cc(OCCn2ccnc2)c1>>CC(O)C(=O)O.c1cc(Nc2nccc(-c3cccs3)n2)cc(OCCn2ccnc2)c1,,CCO,,,,test
US20080085890A1,CN1CCN(c2ccc(NC=C3C(=O)NC(=O)c4ccc(-c5cc[nH]c5)cc43)cc2)CC1.NC(=O)CBr>>CN1CCN(c2ccc(NC=C3C(=O)NC(=O)c4ccc(-c5ccn(CC(N)=O)c5)cc43)cc2)CC1,,CC(C)=O,CN(C)C=O,[I-].[K+],O=C([O-])O.[Na+],test
US04748253,CCC(=O)Cl.CCC(=O)Nc1ccccc1>>CCC(=O)Nc1ccc(C(=O)CC)cc1,,S=C=S,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US04479953,NNC(=O)c1ccccc1.Nc1nc(Cl)c(Cl)nc1C=O>>Nc1nc(Cl)c(Cl)nc1C=NNC(=O)c1ccccc1,,CCO,,,,test
US20100305052A1,CC(=O)C1=C(C)Nc2cc[nH]c(=O)c2C1c1cccc2c(=O)cc(C)oc12.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(=O)C1=C(C)Nc2ccnc(OS(=O)(=O)C(F)(F)F)c2C1c1cccc2c(=O)cc(C)oc12,,c1ccncc1,,,,test
US20040266789A1,BrCc1ccc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)cc1.COC(=O)[C@H](CS)NC(=O)OC(C)(C)C>>COC(=O)[C@H](CSCc1ccc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)cc1)NC(=O)OC(C)(C)C,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20110092415A1,CCOC(C)=O.CN(C)C=O.CN1CCOCC1.COC(=O)N[C@H](C(=O)O)C(C)C.Fc1cc2nc([C@@H]3CCCN3)[nH]c2cc1[C@H]1CC[C@H](c2cc3[nH]c([C@@H]4CCCN4)nc3cc2F)N1c1cc(F)c(N2CCCCC2)c(F)c1.On1nnc2ccccc21>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc2cc([C@H]3CC[C@H](c4cc5nc([C@@H]6CCCN6C(=O)[C@@H](NC(=O)OC)C(C)C)[nH]c5cc4F)N3c3cc(F)c(N4CCCCC4)c(F)c3)c(F)cc2[nH]1)C(C)C,,CN(C)C=O,,ClCCCl,,test
US20090036445A1,C#Cc1ccc(F)cc1F.CC(C)(C)Cn1c(N)nc2ccc(Br)nc21>>CC(C)(C)Cn1c(N)nc2ccc(C#Cc3ccc(F)cc3F)nc21,,Cc1ccccc1,,CCN(CC)CC,,test
US20120309739A1,COc1nc(NCCO)nc2oc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)c12>>NC1(c2ccc(-c3oc4nc(NCCO)[nH]c(=O)c4c3-c3ccccc3)cc2)CCC1,,C1COCCO1,,Cl,,test
US20120238539A1,COc1ccccc1-c1ncn(C)c1CO>>COc1ccccc1-c1ncn(C)c1C=O,O=[Mn]=O,C1COCCO1,,,,test
US06011174,CCOC(=O)CN(C(=O)[C@]1(C(=O)OCC)OC[C@@H](C(=O)OC(C)(C)C)O1)[C@H](C)[C@H](CCc1ccccc1)c1ccc(Oc2ccccc2)cc1>>C[C@H]([C@H](CCc1ccccc1)c1ccc(Oc2ccccc2)cc1)N(CC(=O)O)C(=O)[C@]1(C(=O)O)OC[C@@H](C(=O)O)O1,,O=CO,,,,test
US20030087936A1,CC(CCCCCBr)Oc1ccc(Br)cc1.O=C1NCCN1c1ccc(F)cc1>>O=C1N(CCCCCCOc2ccc(Br)cc2)CCN1c1ccc(F)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20150057265A1,C1COCCN1.CCOC(=O)c1c(NC(=O)OC(C)(C)C)oc2cc(CCC=O)cnc12>>CCOC(=O)c1c(NC(=O)OC(C)(C)C)oc2cc(CCCN3CCOCC3)cnc12,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070117986A1,CC(C)(C)OC(=O)N1CC[C@H](CNS(=O)(=O)C(F)(F)F)C1>>O=S(=O)(NC[C@H]1CCNC1)C(F)(F)F,,ClCCl,,CCN(CC)CC,CCO,test
US20130172407A1,CCCCCCCC/C=C\CCCCCCCC(=O)O.CN(C)C=O>>CCCCCCCC/C=C\CCCCCCCC(=O)NCCO,,ClCCl,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20150094328A1,O=P(Cl)(Cl)Cl.[O-][n+]1cccc2[nH]ccc21>>Clc1ccnc2cc[nH]c12,,O,,,,test
US20100125076A1,CC(=O)Nc1ccc(S(=O)(=O)NCCCN2CCOCC2)cc1>>Nc1ccc(S(=O)(=O)NCCCN2CCOCC2)cc1,,ClC(Cl)Cl,,,,test
US20130150341A1,COC(=O)Cn1nc(-c2ccc(F)cc2)nc1-c1ccc(F)cc1>>O=C(O)Cn1nc(-c2ccc(F)cc2)nc1-c1ccc(F)cc1,,C1COCCO1,O,Cl,[Li+].[OH-],test
US20100197711A1,CC(=O)c1cccc(-c2ccc(C(=O)O)o2)c1.NNc1nc2ccccc2s1>>CC(=NNc1nc2ccccc2s1)c1cccc(-c2ccc(C(=O)O)o2)c1,,CCO,,,,test
US07541367B2,COC(=O)c1cccc2[nH]c(-c3n[nH]c4ncc(-c5cncc6ccccc56)cc34)nc12>>O=C(O)c1cccc2[nH]c(-c3n[nH]c4ncc(-c5cncc6ccccc56)cc34)nc12,,CO,,Cl,[Na+].[OH-],test
US20150126763A1,COS(=O)(=O)OC.Cc1cc(O)c2ccccc2c1O>>COc1cc(C)c(OC)c2ccccc12,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080207708A1,Nc1ccccc1N.O=C(O)c1csc(Cc2cc(Cl)ccc2OCc2ccccc2)n1>>Clc1ccc(OCc2ccccc2)c(Cc2nc(-c3nc4ccccc4[nH]3)cs2)c1,,O=P(Cl)(Cl)Cl,,O=C([O-])O.[Na+],,test
US06013663,COC(=O)CCCCNC(=O)CCCCC1CCSS1>>O=C(O)CCCCNC(=O)CCCCC1CCSS1,,CO,,[Na+].[OH-],,test
US20150023916A1,CCOc1ccc(-n2c[n+]([O-])c3cc(N)ccc32)cc1.CCc1ccc(C=O)cc1>>CCOc1ccc(-n2c[n+]([O-])c3cc(NCc4ccc(CC)cc4)ccc32)cc1,,CO,,[BH4-].[Na+],,test
US20050059651A1,C1CCNC1.O=C1CCc2ccc([N+](=O)[O-])cc2O1>>O=C(CCc1ccc([N+](=O)[O-])cc1O)N1CCCC1,,C1CCOC1,,,,test
US20150045349A1,CC(=O)CC(=O)NC(C)C(C)C.COC(OC)N(C)C>>CC(=O)C(=CN(C)C)C(=O)NC(C)C(C)C,,CN(C)C=O,,,,test
US20100041637A1,C[C@@H](c1ccc(Br)cc1)N1CCC[C@](CC2(C)CO2)(c2ccccc2)OC1=O>>C[C@@H](c1ccc(Br)cc1)N1CCC[C@](CC(C)(C)O)(c2ccccc2)OC1=O,,C1CCOC1,,,,test
US20050113340A1,CO.COc1cc(Cn2cnc3c(Cl)nc(N)nc32)c(Br)c(OC)c1OC>>COc1cc(Cn2cnc3c(OC)nc(N)nc32)c(Br)c(OC)c1OC,,CO,,CO[Na],,test
US04200758,C#CCN1CC(=O)N(CO)C1=O.CC(C)C1C(=O)OC(=O)N1c1ccc(Cl)cc1>>C#CCN1CC(=O)N(COC(=O)C(Nc2ccc(Cl)cc2)C(C)C)C1=O,,C1CCOC1,,CN(C)c1ccccn1,,test
US20080051399A1,Clc1ncnc2c1CCC2.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1cnc(Cl)c2c1CCC2,,ClC(Cl)Cl,,,,test
US04271314,CC(=O)CCCC#CCCCO.O=[Cr](=O)=O>>CC(=O)CCCC#CCCC(=O)O,,CC(C)=O,,O=S(=O)(O)O,,test
US20100069347A1,C=CC[Sn](CCCC)(CCCC)CCCC.CC(=O)O[C@@H](CC[C@H]1C(=O)N(c2ccc(OS(=O)(=O)C(F)(F)F)cc2)[C@@H]1c1ccc(I)cc1)c1ccc(F)cc1>>C=CCc1ccc([C@@H]2[C@@H](CC[C@H](OC(C)=O)c3ccc(F)cc3)C(=O)N2c2ccc(OS(=O)(=O)C(F)(F)F)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,[Cl-].[Li+],,test
US20100292221A1,Cc1ccc(NS(=O)(=O)c2cccc(OC(F)F)c2)cc1N1CCN(C(=O)OC(C)(C)C)CC1.Cl>>Cc1ccc(NS(=O)(=O)c2cccc(OC(F)F)c2)cc1N1CCNCC1.Cl,,CCOCC,ClCCl,,,test
US05728695,C=CC[Mg]Cl.O=C1OCCN(Cc2ccccc2)[C@H]1c1ccc(F)cc1>>C=CC[C@@]1(O)OCCN(Cc2ccccc2)[C@H]1c1ccc(F)cc1,,C1CCOC1,,,,test
US20110212958A1,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)N[C@@H](C)C(=O)Oc1ccc(-c2sc3cc(O[Si](C)(C)C(C)(C)C)ccc3c2C(=O)c2ccc(OCCN3CCOCC3)cc2)cc1>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)N[C@@H](C)C(=O)Oc1ccc(-c2sc3cc(O)ccc3c2C(=O)c2ccc(OCCN3CCOCC3)cc2)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20050187209A1,CC(C)(C)OC(=O)c1cc(C#N)c(S(C)(=O)=O)s1.NN>>CC(C)(C)OC(=O)c1cc(C#N)c(NN)s1,,CCOC(C)=O,CO,O,,test
US04202977,COc1ccccc1N1CCNCC1.ClCCCc1nc2ccccn2n1>>COc1ccccc1N1CCN(CCCc2nc3ccccn3n2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05973008,COc1cc([N+](=O)[O-])ccc1N.Clc1ccccc1>>COc1cc([N+](=O)[O-])ccc1-c1ccc(Cl)cc1,[Cu],,,CC(C)(C)ON=O,,test
US05025031,O=C=NS(=O)(=O)Cl.Oc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>NS(=O)(=O)Oc1cc(C(F)(F)F)cc(C(F)(F)F)c1,,Cc1ccccc1,,,,test
US20030078251A1,CCI.O=Cc1ccc(O)c([N+](=O)[O-])c1>>CCOc1ccc(C=O)cc1[N+](=O)[O-],,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20060084640A1,O=C(Cc1ccccc1)c1cc(F)c(F)c(F)c1.O=C1CCC(=O)N1Br>>O=C(C(=O)c1cc(F)c(F)c(F)c1)c1ccccc1,,CS(C)=O,,,,test
US20080161280A1,CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)CC1Cc1n[nH]c(=O)c2c1CCCC2>>CC(C)(C)OC(=O)N1CCNCC1Cc1n[nH]c(=O)c2c1CCCC2,[Pd],C1CCOC1,,,,test
US20100210674A1,CC(C)(C)OC(=O)C(C)(C)Oc1ccc(Cl)cc1/C=C1\C(=O)Nc2cc(Cl)ccc21.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1C(=O)/C(=C\c2cc(Cl)ccc2OC(C)(C)C(=O)OC(C)(C)C)c2ccc(Cl)cc21,CN(C)c1ccncc1,ClCCl,,,,test
US04888345,CN(C)C=CC(=O)c1ccccc1.NC(=O)c1[nH]cnc1N>>NC(=O)c1ncn2c(-c3ccccc3)ccnc12,,CC(=O)O,ClCCl,Cl,O=C([O-])O.[Na+],test
US04242278,O=C(O)CCC(Br)(Br)Br.O=S(Cl)Cl>>O=C(Cl)CCC(Br)(Br)Br,,CN(C)C=O,,,,test
US20080207900A1,CC(O)[C@@H]1COC[C@@H](c2cc(F)c(F)c(F)c2)N1.O=C(Cl)C(=O)Cl>>CC1OC(=O)C(=O)N2[C@@H]1COC[C@H]2c1cc(F)c(F)c(F)c1,,O,,ClCCl,c1ccncc1,test
US04380638,Cc1nc(CCl)no1.NCCS>>Cc1nc(CSCCN)no1,,CO,,Cl,C[O-].[Na+],test
US20060111375A1,COc1cc2c(Oc3cc(C)c(C)nc3-c3nc(C)c(C)s3)ccnc2cc1O.OCCCBr>>COc1cc2c(Oc3cc(C)c(C)nc3-c3nc(C)c(C)s3)ccnc2cc1OCCCO,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090149468A1,COC(CN)OC.CSc1nc(Cl)cc(-c2ccnc(Cl)c2)n1>>COC(CNc1cc(-c2ccnc(Cl)c2)nc(SC)n1)OC,,ClCCl,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20060063759A1,CC(C)(C)OOC(C)(C)C.CS(=O)(=O)Nc1cccc(C=C2c3ccccc3CS(=O)c3ccccc32)c1>>CS(=O)(=O)Nc1cccc(C=C2c3ccccc3CS(=O)(=O)c3ccccc32)c1,,ClCCl,,,,test
US20140309225A1,O=P(Cl)(Cl)Cl.[O-][n+]1cc(Br)c2cn[nH]c2c1>>Clc1ncc(Br)c2cn[nH]c12,,O,,,,test
US05393790,COC(=O)CC(=O)OC.CS(=O)(=O)c1ccc(C(=O)CBr)cc1.O=C(CBr)c1ccc(F)cc1>>COC(=O)C(CC(=O)c1ccc(F)cc1)(CC(=O)c1ccc(S(C)(=O)=O)cc1)C(=O)OC,,CN(C)C=O,,[H-].[Na+],,test
US20160002273A1,CCNC(=O)c1cccc(C(=O)O)c1.NCCC1CCN(c2ncnc3cc(C(N)=O)sc23)CC1>>CCNC(=O)c1cccc(C(=O)NCCC2CCN(c3ncnc4cc(C(N)=O)sc34)CC2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060252758A1,C=O.CCCCCN1C(=O)C(c2cc3c(cc2O)OCO3)c2ncccc21>>CCCCCN1C(=O)C(CO)(c2cc3c(cc2O)OCO3)c2ncccc21,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20050107419A1,CCOC(=O)C1=C(CCc2ccc(F)cc2)NC([C@@H]2CCCN2C(=O)OC(C)(C)C)=C(C(=O)OCC)C1c1ccc(C)cc1>>CCOC(=O)c1c(CCc2ccc(F)cc2)nc2c(c1-c1ccc(C)cc1)C(=O)N1CCC[C@@H]21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060135614A1,COc1c(C(C)C)cc(Oc2c(Cl)cc(C(=O)N(C)CC(=O)O)cc2Cl)cc1[N+](=O)[O-]>>COc1c(N)cc(Oc2c(Cl)cc(C(=O)N(C)CC(=O)O)cc2Cl)cc1C(C)C,O=[Pt]=O,CCOC(C)=O,,,,test
US20140243311A1,CCCN(C(=O)Oc1ccc([N+](=O)[O-])cc1)C(=O)[C@@H]1C[C@@H]2Cc3c(sc(N(C)C(=O)OC(C)(C)C)c3C#N)C[C@H]2N(C)C1.CN(C)CCN>>CCCN(C(=O)NCCN(C)C)C(=O)[C@@H]1C[C@@H]2Cc3c(sc(N(C)C(=O)OC(C)(C)C)c3C#N)C[C@H]2N(C)C1,,C1CCOC1,,,,test
US20090137561A1,COC(=O)c1ccc(-c2cc(OC)ccc2F)c(C2C(=O)CCC2C)c1>>COC(=O)c1ccc(-c2cc(OC)ccc2F)c(C2C(C)CCC2O)c1,,C1CCOC1,CO,[BH4-].[Na+],,test
US03991082,CC(C)N.O=C(CBr)c1coc2ccccc2c1=O>>CC(C)NC=C1C(=O)COc2ccccc2C1=O,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20010053853A1,CCN(C(C)C)C(C)C.CCO.CCOC(=O)CC(CCCCCCCN)c1cnc(C)nc1.Clc1ncccn1>>CCOC(=O)CC(CCCCCCCNc1ncccn1)c1cnc(C)nc1.CC[O-].[NH4+],,CCO,,,,test
US04673746,COc1ccc(C(=O)c2ccccc2F)c(O)c1Cl.NO>>COc1ccc(/C(=N\O)c2ccccc2F)c(O)c1Cl,,c1ccncc1,,Cl,,test
US20060111375A1,COc1cc2nccc(Oc3ccc(C)nc3I)c2cc1OC.Cc1ccccc1B(O)O>>COc1cc2nccc(Oc3ccc(C)nc3-c3ccccc3C)c2cc1OC,,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US05451601,F[C@@H]1CCC(c2ccccc2)(c2ccccc2)[C@@H]2CNC[C@H]12.O=C(O)Cc1ccccc1N1CCCC1>>O=C(Cc1ccccc1N1CCCC1)N1C[C@@H]2[C@H](F)CCC(c3ccccc3)(c3ccccc3)[C@@H]2C1,,CCN(CC)CC,ClCCl,Cl,O=C(n1ccnc1)n1ccnc1,test
US04410458,CC1(CCl)S[C@@H]2C(NC(=O)Cc3ccccc3)C(=O)N2C1C(=O)OCC(Cl)(Cl)Cl>>CC1=C(C(=O)OCC(Cl)(Cl)Cl)N2C(=O)C(NC(=O)Cc3ccccc3)[C@H]2SC1,,c1ccncc1,,,,test
US05614633,O=C(OO)c1cccc(Cl)c1.O=[N+]([O-])c1ccc2c(c1)C(c1ccccn1)=CC(C(F)(F)F)(C(F)(F)F)O2>>O=[N+]([O-])c1ccc2c(c1)C(c1cccc[n+]1[O-])=CC(C(F)(F)F)(C(F)(F)F)O2,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20150087646A1,NCc1ccc(Cl)c(-c2nn(-c3ccc(C(F)(F)F)cc3)c(=O)[nH]2)c1.O=S(=O)(Cl)C1CC1>>O=c1[nH]c(-c2cc(CNS(=O)(=O)C3CC3)ccc2Cl)nn1-c1ccc(C(F)(F)F)cc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090029963A1,NNc1cccc(C(F)(F)F)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NNc1cccc(C(F)(F)F)c1)C(F)(F)F,,C1CCOC1,,,,test
US20070265302A1,COC(=O)C1CCC(C#C[Si](C)(C)C)N1C(=O)[C@@H](NC(=O)OC(C)(C)C)C1CCCC1>>C#C[C@H]1CC[C@@H](C(=O)O)N1C(=O)[C@@H](NC(=O)OC(C)(C)C)C1CCCC1,,CO,O,[Li]O,,test
US20050192359A1,COc1ccc(-c2ccccc2[N+](=O)[O-])cc1OC>>COc1ccc(-c2ccccc2N)cc1OC,[Pt],Cc1ccccc1,,NN,O,test
US20070292545A1,COc1cc(CO)cc(OC)c1>>COc1cc(C=O)cc(OC)c1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20040122016A1,CC(C)(C)OC(=O)N1CCC(CCCO)CC1.COC(=O)Cc1cccc(O)c1>>COC(=O)Cc1cccc(OCCCC2CCN(C(=O)OC(C)(C)C)CC2)c1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080039457A1,CC(C)(C)OC(=O)[C@@H](NC(=O)c1ccc(-c2cnc3nnc(C4(c5ccc6ncsc6c5)CC4)n3n2)cc1)C(C)(C)C>>CC(C)(C)[C@H](NC(=O)c1ccc(-c2cnc3nnc(C4(c5ccc6ncsc6c5)CC4)n3n2)cc1)C(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110312969A1,CC(C)(C)OC(=O)N=c1n(CCCOc2ccc(F)cc2)c2ccccc2n1Cc1ccccc1N1CCN(Cc2ccccc2-c2ccccc2)CC1>>N=c1n(CCCOc2ccc(F)cc2)c2ccccc2n1Cc1ccccc1N1CCN(Cc2ccccc2-c2ccccc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070054887A1,CC(C)(O)CC=CC1(C2=CC[C@H]3C(=O)CCC[C@@]23C)CC1.C[Si](C)(C)c1ncc[nH]1>>CC(C)(CCCC1(C2=CC[C@H]3C(=O)CCC[C@@]23C)CC1)O[Si](C)(C)C,,ClCCl,,,,test
US20090325939A1,COc1ccc2c(C(=O)N3CCN4CCC3CC4)nsc2c1>>O=C(c1nsc2cc(O)ccc12)N1CCN2CCC1CC2,,ClCCCl,ClCCl,BrB(Br)Br,,test
US04846882,CC1(C)CON(Cc2cc([N+](=O)[O-])c(F)cc2Cl)C1=O>>CC1(C)CON(Cc2cc(N)c(F)cc2Cl)C1=O,O=[Pt],CCO,,,,test
US20090181942A1,CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2Cl)c2cc(C)ccc2-n2c1nnc2C(F)(F)F>>COc1cccc([C@H]2O[C@H](CC(=O)O)c3nnc(C(F)(F)F)n3-c3ccc(C)cc32)c1Cl,,C1COCCO1,,Cl,,test
US20160237090A1,Fc1ccc(-c2cnn3c2CNCC3)cc1.O=C(Nc1ccc(F)c(Cl)n1)Oc1ccccc1>>O=C(Nc1ccc(F)c(Cl)n1)N1CCn2ncc(-c3ccc(F)cc3)c2C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20150307450A1,COc1ccc(C#N)cc1/C=C(\C#N)c1cn(C(=O)C[C@H](C)NC(=O)OC(C)(C)C)c2ccc(Br)cc12.Cl>>COc1ccc(C#N)cc1/C=C(\C#N)c1cn(C(=O)C[C@H](C)N)c2ccc(Br)cc12.Cl,,CCO,,,,test
US05576324,Cc1cc2c3c(cc(C)c2[nH]c1=O)CC(CBr)O3.[N-]=[N+]=[N-]>>Cc1cc2c3c(cc(C)c2[nH]c1=O)CC(CN=[N+]=[N-])O3,,ClC(Cl)Cl,,CN(C)C=O,,test
US20120258950A1,Clc1ncc(Br)c(Cl)n1.NC12CC(C1)C2>>Clc1ncc(Br)c(NC23CC(C2)C3)n1,,CC#N,,,,test
US20150099888A1,COc1cc(Nc2ncccc2C=O)cc(OC)c1OC.COc1ccc(C(C)=O)cc1>>COc1ccc(C(=O)/C=C/c2cccnc2Nc2cc(OC)c(OC)c(OC)c2)cc1,,CO,,Cl,,test
US20090227575A1,CS(=O)(=O)n1ccc2c3nc(-c4ccc(N)cc4)nc(N4CCOCC4)c3ccc21.O=C=Nc1ccccc1>>CS(=O)(=O)n1ccc2c3nc(-c4ccc(NC(=O)Nc5ccccc5)cc4)nc(N4CCOCC4)c3ccc21,,ClCCl,,CCN(CC)CC,,test
US20100048842A1,C1COCCN1.O=C1CCCCC1=O>>O=C1CCCC=C1N1CCOCC1,,Cc1ccccc1,,N#N,,test
US06069132,CCCCCCBr.Nc1ncnc2pc[nH]c12>>CCCCCCn1cpc2ncnc(N)c21,,CN(C)C=O,,CO,[H-].[Na+],test
US20100324073A1,COc1cccc(C(C#N)C(=O)Cc2ccccc2)c1.NN>>COc1cccc(-c2c(N)n[nH]c2Cc2ccccc2)c1,,Cl,,CCO,O,test
US20110152326A1,CON(C)C(=O)CNC(=O)OC(C)(C)C.FC(F)(F)c1cccnc1Br>>CC(C)(C)OC(=O)NCC(=O)c1ncccc1C(F)(F)F,,CCCCCC,Cc1ccccc1,[Li]CCCC,,test
US04677115,O=C1CCCc2sccc21>>OC1CCCc2sccc21,,CCO,,O,[BH4-].[Na+],test
US04962115,CS(=O)(=O)Cl.O=[N+]([O-])c1cc(F)ccc1OC1CCC(O)CC1>>CS(=O)(=O)OC1CCC(Oc2ccc(F)cc2[N+](=O)[O-])CC1,,ClC(Cl)Cl,,c1ccncc1,,test
US20080207606A1,CCN(C(C)C)C(C)C.CS(=O)(=O)c1ccc(-c2nc(C(F)(F)F)nc(N3CCC(C(=O)O)CC3)c2-c2ccc(F)cc2)cc1.On1nnc2ccccc21>>CONC(=O)C1CCN(c2nc(C(F)(F)F)nc(-c3ccc(S(C)(=O)=O)cc3)c2-c2ccc(F)cc2)CC1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20130053382A1,CC(C)(C)OC(=O)N1Cc2ccc(-c3cc4cnn(COCC[Si](C)(C)C)c4cc3N)cc2C1.O=C(O)c1csc(C#CC2CC2)n1>>CC(C)(C)OC(=O)N1Cc2ccc(-c3cc4cnn(COCC[Si](C)(C)C)c4cc3NC(=O)c3csc(C#CC4CC4)n3)cc2C1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080004269A1,CCCc1c(NN)ncnc1C(C(=O)OCC)c1ccnn1-c1ncccc1Br>>CCCC1=C(Cc2ccnn2-c2ncccc2Br)N=CNC1NN,,Cl,,O=C([O-])O.[Na+],,test
US20070185133A1,CC(C)(C)OC(=O)N1CCN(CCOc2ccc3sc(-c4nc(NCCN5C(=O)NC(=O)C5(C)C)ncc4Br)cc3c2)CC1>>CC1(C)C(=O)NC(=O)N1CCNc1ncc(Br)c(-c2cc3cc(OCCN4CCNCC4)ccc3s2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100144760A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)[Si](OC[C@@H]1C[C@H]2C[C@H]2CN1)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H]2C[C@H]1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,ClCCl,,,,test
US20150290342A1,Cc1ccc(SCC(CSc2ccc(C)cc2)C(=O)c2ccc(C(=O)NC(CC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc2)cc1>>Cc1ccc(SCC(CSc2ccc(C)cc2)C(=O)c2ccc(C(=O)NC(CC(=O)O)C(=O)O)cc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150005258A1,CNCCCC(=O)NCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.N=C(N)n1cccn1.[Br-]>>CN(CCCC(=O)NCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1)C(=N)N.[Br-],,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US08304419B2,C[Si](C)(C)CCOCn1cnc(Cl)c1C=O>>C[Si](C)(C)CCOCn1cnc(Cl)c1CO,,CO,,[BH4-].[Na+],,test
US20120202785A1,Cc1ccc([N+](=O)[O-])c(Nc2ccccc2)c1>>Cc1ccc(N)c(Nc2ccccc2)c1,[Pd],CCOC(C)=O,,,,test
US04006237,CCCN(C(C)=O)C1=C(C(=O)O)CCCC1>>CCCn1c2c(c(O)cc1=O)CCCC2,,CCO,,,,test
US20100324030A1,COc1cnc2cccc(B3OC(C)(C)C(C)(C)O3)c2c1.OO>>COc1cnc2cccc(O)c2c1,,C1CCOC1,,[Na+].[OH-],,test
US03933836,CC(C)N=C=NC(C)C.N=c1ccccn1CCc1ccccc1Br>>CC(C)N=C(N=c1ccccn1CCc1ccccc1Br)NC(C)C,,CC(C)(C)O,,,,test
US20010046975A1,CCCCCCC(C)NC(C)=O>>CCCCCCC(C)NCC,,C1CCOC1,,B,CSC,test
US20100029737A1,COC(=O)c1cc2c([nH]1)CCC2Cc1cccc(-c2ccccc2)c1>>O=C(O)c1cc2c([nH]1)CCC2Cc1cccc(-c2ccccc2)c1,,C1CCOC1,,CO,[Li+].[OH-],test
US04563474,CC(C#N)=CCCl.O=C1NS(=O)(=O)c2ccccc21>>CC(C#N)=CCN1C(=O)c2ccccc2S1(=O)=O,,CN(C)C=O,,[Na],,test
US20100168082A1,CC1Cc2c(Cl)ncnc2CN1C(=O)OC(C)(C)C.Oc1ccc2[nH]ccc2c1>>CC1Cc2c(ncnc2Oc2ccc3[nH]ccc3c2)CN1C(=O)OC(C)(C)C,,CC#N,,C1CCC2=NCCCN2CC1,,test
US05130443,Nc1ccccc1.O=C(Oc1ccccc1)c1cc2ccc3c4ccccc4[nH]c3c2cc1O>>O=C(Nc1ccccc1)c1cc2ccc3c4ccccc4[nH]c3c2cc1O,,CN1CCCC1=O,,,,test
US20030069297A1,Cc1cc(C(=O)N2CCN(C)CC2)c(C=O)[nH]1.O=C1Cc2c(cccc2-c2ccc(F)cc2)N1>>Cc1cc(C(=O)N2CCN(C)CC2)c(C=C2C(=O)Nc3cccc(-c4ccc(F)cc4)c32)[nH]1,C1CCNCC1,CCO,,,,test
US20120322784A1,CC(C)(C)OC(=O)N1CCC(C2Cc3cc(N4CCNCC4)ncc3O2)CC1.O=S(=O)(Cl)C1CC1>>CC(C)(C)OC(=O)N1CCC(C2Cc3cc(N4CCN(S(=O)(=O)C5CC5)CC4)ncc3O2)CC1,,ClCCl,,CCN(CC)CC,,test
US05721185,[Li]CCCC.c1ccc2c(c1)CC1=C2CCCC1>>[Li+].c1ccc2c(c1)CC1=C2CCC[CH-]1,,CCCCC,,,,test
US20120238574A1,CC(C)(O)CN.Nc1ccc(C=C2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)(O)CNC(=O)Nc1ccc(C=C2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1,,C1COCCO1,,,,test
US20120283273A1,N#Cc1cc(Cl)ncn1.NCc1cnc2[nH]c(C(F)(F)F)cc2c1>>N#Cc1cc(NCc2cnc3[nH]c(C(F)(F)F)cc3c2)ncn1,,CCOC(C)=O,CN1CCCC1=O,CCN(C(C)C)C(C)C,,test
US04766133,CO.COc1c(C)cnc(CSc2nc3ccc(C(F)(F)F)cc3[nH]2)c1C>>COc1c(C)cnc(CS(=O)c2nc3ccc(C(F)(F)F)cc3[nH]2)c1C,,ClCCl,,,,test
US20130317024A1,COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(C2CCN(C(=O)OC(C)(C)C)CC2)C3=O)c(OC)n1>>COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(C2CCNCC2)C3=O)c(OC)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130237555A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2cc3c(cn2)C(C)Oc2cc(OC[C@H](CC(C)C)NC(=O)OC(C)(C)C)ccc2-3)cc1>>CC(C)C[C@H](N)COc1ccc2c(c1)OC(C)c1cnc(N)cc1-2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140275071A1,Cc1ccc(O)cn1.Cn1c(=O)n(CCCOC2CCCCO2)c(=O)c2c1nc(Br)n2Cc1ccc(Cl)cc1>>Cc1ccc(Oc2nc3c(c(=O)n(CCCOC4CCCCO4)c(=O)n3C)n2Cc2ccc(Cl)cc2)cn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05001125,CCOC(=O)N1CCC(Nc2cccc(C)c2C)C1>>Cc1cccc(NC2CCNC2)c1C,,CC(C)O,,[K+].[OH-],,test
US20060189613A1,O=S(=O)(Nc1nnc(Cl)cc1Br)c1cccc(Cl)c1Cl.OCc1cccnc1>>O=S(=O)(Nc1nnc(Cl)cc1OCc1cccnc1)c1cccc(Cl)c1Cl,,COCCOC,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20120052757A1,CC(=O)Oc1cc(C(=O)O)cc(OC(C)=O)c1OC(C)=O.Cc1ccccc1>>CC(=O)Oc1cc(/C=C/c2ccccc2)cc(OC(C)=O)c1OC(C)=O,,Cc1ccccc1,,O=S(Cl)Cl,,test
US20150291595A1,CCOC(=O)/C(C#N)=C(\NCc1ccc(OC)cc1)SC.N=CN>>CCOC(=O)/C(C#N)=C(/N=C/N)NCc1ccc(OC)cc1,,CCO,,CCN(C(C)C)C(C)C,Cl,test
US20100249119A1,Cc1ccc(NC(=O)OC(C)(C)C)cc1O.O=[N+]([O-])c1ccc(Cl)nc1>>Cc1ccc(NC(=O)OC(C)(C)C)cc1Oc1ccc([N+](=O)[O-])cn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080009530A1,CCOC(=O)/C=C/c1cc(OCOC)nn1Cc1ccc(Cl)cc1Cl>>CCOC(=O)/C=C/c1cc(O)nn1Cc1ccc(Cl)cc1Cl,,CO,,Cl,,test
US20100137313A1,COc1cc(Nc2ncc(-c3cnc(OC)c(C(=O)O)c3)c(-n3nc(C(F)(F)F)cc3C)n2)cc(OC)c1.CS(=O)(=O)CS(N)(=O)=O>>COc1cc(Nc2ncc(-c3cnc(OC)c(C(=O)NS(=O)(=O)CS(C)(=O)=O)c3)c(-n3nc(C(F)(F)F)cc3C)n2)cc(OC)c1,CN(C)c1ccncc1,ClCCl,ClCCl,CCN(CC)CC,C[n+]1ccccc1Cl.[I-],test
US20120114739A1,CCOC(=O)CC(=O)C1CCC(C(=O)OC)CC1.Nc1cc[nH]n1>>COC(=O)C1CCC(c2cc(O)n3nccc3n2)CC1,,ClCCl,,,,test
US05556864,CN1C[C@H](O)CC1COc1ccccc1CCc1ccccc1.Cl>>CN1C[C@H](O)CC1COc1ccccc1CCc1ccccc1.Cl,,C1COCCO1,,,,test
US06608070B1,COC(=O)Cc1c(C(=O)c2ccc(Cl)cc2)[nH]c2cc(Cl)ccc12>>O=C(O)Cc1c(C(=O)c2ccc(Cl)cc2)[nH]c2cc(Cl)ccc12,,C1CCOC1,CO,[Na+].[OH-],,test
US05656629,CCc1nn(C2CCCC2)c(N)c1C(N)=O.COc1ccc(CC(=O)[O-])cc1>>CCc1[nH]n(C2CCCC2)c2nc(Cc3ccc(OC)cc3)nc(=O)c1-2,,CCO,,O,[Na],test
US20090197862A1,Cc1nc(O)cc2ccccc12.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1nc(OS(=O)(=O)C(F)(F)F)cc2ccccc12,,ClCCl,,CCN(CC)CC,,test
US20060189623A1,C=CC#N.N#Cc1c[nH]c(C(=O)Nc2ccc(C3CCNCC3)cc2C2=CCCCC2)n1.O=C(O)C(F)(F)F>>N#CCCN1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1.O=C(O)C(F)(F)F,,ClCCCl,,CCN(CC)CC,CO,test
US20100113611A1,CO.O=C(O)C(O)c1ccc(O)c(O)c1>>COC(=O)Cc1ccc(O)c(O)c1,[Pd],Cl,,[H][H],,test
US20080021221A1,COc1cc(O)c(C(=O)O)cc1OC.Oc1ccccc1>>COc1cc(O)c(C(=O)Oc2ccccc2)cc1OC,,Cc1ccccc1C,,O=S(Cl)Cl,,test
US20110237573A1,Nc1ccc(-c2cccnn2)cn1.O=C(O)Cc1ccc(-c2ccnc(F)c2)c(F)c1>>O=C(Cc1ccc(-c2ccnc(F)c2)c(F)c1)Nc1ccc(-c2cccnn2)cn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120028959A1,O=C1Nc2ccc(Cl)cc2C1=O.O=[N+]([O-])O>>O=C1Nc2c(cc(Cl)cc2[N+](=O)[O-])C1=O,,O=S(=O)(O)O,,,,test
US20100160258A1,CN1C(=O)OC[C@@]1(C)c1ccc2cc(OC3CCC(C(C)(C)C)CC3)ccc2c1>>CN[C@@](C)(CO)c1ccc2cc(OC3CCC(C(C)(C)C)CC3)ccc2c1,,CCO,,[Li+].[OH-],,test
US20070172421A1,C=C(CBr)C(=O)OC.CN=Cc1ccc(Br)s1>>C=C1CC(c2ccc(Br)s2)N(C)C1=O,[Zn],C1CCOC1,,[Cl-].[NH4+],,test
US06329405B1,COc1ccc(C(NCCc2ccccc2)c2cccc(Nc3c(OC)c(=O)c3=O)c2)cc1.N>>COc1ccc(C(NCCc2ccccc2)c2cccc(Nc3c(N)c(=O)c3=O)c2)cc1,,CCO,,,,test
US05922725,CON=Cc1ccc2c(c1)ncn2-c1cccc(Br)c1.OB(O)c1ccoc1>>CON=Cc1ccc2c(c1)ncn2-c1cccc(-c2ccoc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])O.[Na+],,test
US20150252027A1,CC(C)c1cccc(C(C)C)c1O.O=C(Cl)OCCl>>CC(C)c1cccc(C(C)C)c1OC(=O)OCCl,,ClCCl,,CCN(CC)CC,,test
US20090131422A1,C[C@H]1CN(C(=O)CN2CC(C)(C)OC[C@H]2C(=O)Nc2cc(Cl)cc3c2[nH]c2cnccc23)C[C@@H](C)O1.Cc1ccc(S(=O)(=O)O)cc1.O>>C[C@H]1CN(C(=O)CN2CC(C)(C)OC[C@H]2C(=O)Nc2cc(Cl)cc3c2[nH]c2cnccc23)C[C@@H](C)O1.Cc1ccc(S(=O)(=O)O)cc1.O,,O,,,,test
US20130079321A1,Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2NC(=O)OC(C)(C)C)c1N1CC[C@@H](NC(=O)C(F)(F)F)C2(CCO2)CC1>>Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCC(N)C2(CCO2)CC1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20150361059A1,CC(C)(C)OC(=O)N[C@H]1COc2c(cccc2C(F)(F)F)NC1=O.COc1ccc2cc(Br)ccc2c1CCl>>COc1ccc2cc(Br)ccc2c1CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)COc2c1cccc2C(F)(F)F,,CCOC(C)=O,CN(C)C=O,[I-].[Na+],O=C([O-])[O-].[Cs+].[Cs+],test
US20140356322A1,CC(=O)OC(C)=O.Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)cc1>>CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)C,,C1COCCO1,ClCCl,CCN(CC)CC,Cl,test
US20090197862A1,COC(OC)C(=O)NCc1ccc(F)cc1>>Oc1cc2cc(F)ccc2cn1,,ClCCl,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US20060229280A1,CCCCCS(=O)(=O)Cl.CCCN>>CCCCC(CCC)S(N)(=O)=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20130196974A1,O=Cc1ccc([N+](=O)[O-])cc1>>Nc1ccc(C=O)cc1,[Fe],CC(=O)O,O,,,test
US20090264431A1,C[C@H]1C[C@@H](N)CN1C(=O)OC(C)(C)C.O=S(=O)(Cl)c1cc(Cl)ccc1Cl>>C[C@H]1C[C@@H](NS(=O)(=O)c2cc(Cl)ccc2Cl)CN1C(=O)OC(C)(C)C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20050080124A1,CN(C)CCOc1ccc(N)cc1-c1c(Br)cnn1C.O=C=Nc1ccc(F)cc1>>CN(C)CCOc1ccc(NC(=O)Nc2ccc(F)cc2)cc1-c1c(Br)cnn1C,,ClCCl,,,,test
US20060189663A1,CCCCN1C(=O)C(Cl)=C(c2ccccc2)C1=O.COc1ccc(N)cc1>>CCCCN1C(=O)C(Nc2ccc(OC)cc2)=C(c2ccccc2)C1=O,,CCO,,,,test
US20100298290A1,CC(C)(C)OC(=O)N1CCOc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C1.Cl>>CC1(C)OB(c2ccc3c(c2)CNCCO3)OC1(C)C.Cl,,CO,,,,test
US20050032786A1,CCOP(=O)(CCc1ccncc1)OCC.O=C(OO)c1cccc(Cl)c1>>CCOP(=O)(CCc1cc[n+]([O-])cc1)OCC,,CCOC(C)=O,,,,test
US20060069143A1,CN(C)S(=O)(=O)n1cnc(C(O)c2cccs2)c1>>CN(C)S(=O)(=O)n1cnc(Cc2cccs2)c1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US05481032,Cc1ccc(C(=O)c2ccc(F)cc2Cl)cc1.OO>>O=C(O)c1ccc(F)cc1Cl,,C1CCOC1,O,Cc1ccc(S(=O)(=O)O)cc1,,test
US05025025,C=CCC(CCCC#N)COS(C)(=O)=O.CCOC(=O)CC(=O)OCC>>C=CCC(CCCC#N)CC(C(=O)OCC)C(=O)OCC,,C1CCOC1,,CC(=O)O,[H-].[Na+],test
US20080045555A1,NN.O=C(O)COc1ccc(Br)cc1>>NNC(=O)COc1ccc(Br)cc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20070265225A1,CC(=O)OCc1ccccc1.O=C1CSC[C@@H](c2cc(F)cc(F)c2)N1>>O=C(CN1C(=O)CSC[C@H]1c1cc(F)cc(F)c1)OCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US04006245,CCCc1ccccc1OCCCCCCCBr.CCOC(=O)c1cc(=O)c2cccc(O)c2o1>>CCCc1ccccc1OCCCCCCCOc1cccc2c(=O)cc(C(=O)OCC)oc12,,CC(C)=O,,[I-].[K+],,test
US20130078728A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1.Cl>>C[C@H](N)C(=O)OCc1ccccc1.Cl,,C1COCCO1,,N#N,,test
US20080004285A1,CC(C)(C)OC(=O)N1CCNCC1.Fc1ccc(-c2ccc3nc(Cl)nc(Cl)c3n2)cc1>>CC(C)(C)OC(=O)N1CCN(c2nc(Cl)nc3ccc(-c4ccc(F)cc4)nc23)CC1,,C1COCCO1,,,,test
US20040171881A1,CCCCN.COC(=O)c1cc(C)cc(CO)c1>>CCCCNCc1cc(C)cc(C(=O)OC)c1,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20060111375A1,COc1cc2nccc(Cl)c2cc1OC.Cc1cc(O)c(-c2ccccc2)nc1C>>COc1cc2nccc(Oc3cc(C)c(C)nc3-c3ccccc3)c2cc1OC,CN(C)c1ccncc1,Clc1ccccc1Cl,,,,test
US04233299,COC(=O)C1=C(O)c2cc(Cl)ccc2S(=O)(=O)N1C.Cc1cnc(N)s1>>Cc1cnc(NC(=O)C2=C(O)c3cc(Cl)ccc3S(=O)(=O)N2C)s1,,Cc1ccccc1C,,,,test
US20120184542A1,C1CCOC1.CC(C)(C)OC(=O)NCC(O)C1CCCC1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)NCC(C1CCCCC1)N1C(=O)c2ccccc2C1=O,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US05130323,COC(=O)CCC/C=C\[C@@H]1C[C@@H](NS(=O)(=O)c2ccc(Cl)cc2)CN1Cc1ccccc1>>O=C(O)CCC/C=C\[C@@H]1C[C@@H](NS(=O)(=O)c2ccc(Cl)cc2)CN1Cc1ccccc1,,CO,,[Na+].[OH-],,test
US20090197863A1,COC(=O)c1cccc(NC(=O)c2cc3ccccc3[nH]2)c1O>>COC(=O)c1cccc2nc(-c3cc4ccccc4[nH]3)oc12,,Cc1ccccc1C,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20140206681A1,COC(=O)[C@@H]1CC[C@@H](CO)N(C(=O)[C@@H](C)Cl)C1>>COC(=O)[C@@H]1CC[C@H]2CO[C@@H](C)C(=O)N2C1,,C1CCOC1,,[H-].[Na+],,test
US20010053776A1,CC(C)(C)[Si](C)(C)Cl.OCCCc1ccncc1Br>>CC(C)(C)[Si](C)(C)OCCCc1ccncc1Br,,ClCCl,,c1c[nH]cn1,,test
US20130150360A1,C1COCCN1.O=C(O)c1ccc(Br)nc1>>O=C(c1ccc(Br)nc1)N1CCOCC1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050256159A1,CON(C)C(=O)C1CCN(C(=O)c2ccc(F)cc2)CC1.Fc1ccccc1I>>O=C(c1ccccc1F)C1CCN(C(=O)c2ccc(F)cc2)CC1,,CCOCC,,II,[Mg],test
US20090054427A1,BrP(Br)Br.COCc1cc(CO)cc(F)c1[N+](=O)[O-]>>COCc1cc(CBr)cc(F)c1[N+](=O)[O-],,CCOCC,,,,test
US20060142209A1,CSc1ccc(Cc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)n[nH]c2C)cc1.OCCCBr>>Cc1csc(Cc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)nn(CCCO)c2C)c1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US04436662,CCc1[nH]cc(C#N)c1-c1ccc(Cl)cc1C(=O)c1ccccc1Cl>>CCc1[nH]cc2c1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2,[Ni],CC(=O)O,,,,test
US20130116235A1,CN1CCc2nc(Nc3cc(-c4ccnc(N5CCn6c7c(c(F)c6C5=O)CCCC7)c4C=O)cn(C)c3=O)sc2C1>>CN1CCc2nc(Nc3cc(-c4ccnc(N5CCn6c7c(c(F)c6C5=O)CCCC7)c4CO)cn(C)c3=O)sc2C1,,CO,,[BH4-].[Na+],,test
US20020099055A1,CCOC(=O)c1c[nH]cc1C(=O)OCC.ClCc1cccc2ccccc12>>CCOC(=O)c1cn(Cc2cccc3ccccc23)cc1C(=O)OCC,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080280875A1,COC(=O)c1cc(OC)c2nc(N)sc2c1>>COC(=O)c1cc(OC)c2ncsc2c1,,CN(C)C=O,,CC(C)CCON=O,,test
US20070254874A1,O=C(CCCBr)OCC(Cl)(Cl)Cl.OCC1CCNCC1>>O=C(CCCN1CCC(CO)CC1)OCC(Cl)(Cl)Cl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05189046,BrCc1ccccc1.NC(=O)[C@@H]1CCCCN1>>O=C(NCc1ccccc1)[C@@H]1CCCCN1,,ClCCl,,CCN(CC)CC,,test
US05614527,CC(C)C(=O)Cl.O=[N+]([O-])N=C1NCCCN1CC1CCOC1>>CC(C)C(=O)N1CCCN(CC2CCOC2)C1=N[N+](=O)[O-],,CC#N,,[H-].[Na+],,test
US20100029611A1,CC(=O)O[C@@H](CC(=O)O)C(=O)Nc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1>>O=C(O)C[C@H](O)C(=O)Nc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1,,C1CCOC1,,[Na+].[OH-],,test
US05532235,Nc1ccc(C(=O)C2CN=c3ncccc3=C3N=NC=C32)cc1.O=C(Cl)c1ccccc1-c1ccccc1>>O=C(Nc1ccc(C(=O)N2CCc3cn[nH]c3-c3cccnc32)cc1)c1ccccc1-c1ccccc1,,CO,ClCCl,CCN(CC)CC,[Na+].[OH-],test
US20030119670A1,CN(C)C.Cc1ccccc1.ClCc1ccc(-c2ccccc2)cc1>>Cc1ccc(C[N+](C)(C)C)cc1.[Cl-],,Cc1ccccc1,,,,test
US20050070441A1,CCN=C=O.Cc1cc(Oc2c(F)cc(C(F)(F)F)cc2F)n[nH]1>>CCNC(=O)n1nc(Oc2c(F)cc(C(F)(F)F)cc2F)cc1C,,CCOC(C)=O,,CCN(CC)CC,Cl,test
US05252571,CCOC(=O)CC1Sc2ccccc2N(CC#N)C1=O.Nc1ccccc1S>>CCOC(=O)CC1Sc2ccccc2N(Cc2nc3ccccc3s2)C1=O,,O,,Cl,,test
US20140343038A1,CCn1ncc2c(C)cc([N+](=O)[O-])cc21>>CCn1ncc2c(C)cc(N)cc21,[Pd],CCOC(C)=O,,,,test
US20160229853A1,COc1ccc(CN2CC(N)CCC2=O)cc1.O=[N+]([O-])c1cc(Cl)ccc1F>>COc1ccc(CN2CC(Nc3ccc(Cl)cc3[N+](=O)[O-])CCC2=O)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100004229A1,CC(c1ccccc1Br)N(c1cccnc1)c1cccnc1.CC1(C)OB(c2ccc(S(=O)(=O)N3CCCC3)cc2)OC1(C)C>>CC(c1ccccc1-c1ccc(S(=O)(=O)N2CCCC2)cc1)N(c1cccnc1)c1cccnc1,[Pd],C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160185778A1,C[C@@H]1Cc2[nH]nc(C3CCCC3)c2CN1C(=O)OC(C)(C)C>>C[C@@H]1Cc2[nH]nc(C3CCCC3)c2CN1,,C1COCCO1,,Cl,,test
US20100144787A1,CCCC[Sn](CCCC)(CCCC)c1nccn1C.CCc1nc2c(F)ccc(OCC(=O)OC)c2c(OC(F)F)c1Cc1ccc(Br)cc1>>CCc1nc2c(F)ccc(OCC(=O)OC)c2c(OC(F)F)c1Cc1ccc(-c2nccn2C)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20090036495A1,COC(=O)c1cc(Cl)ccc1F.Oc1ccc(F)cc1>>COC(=O)c1cc(Cl)ccc1Oc1ccc(F)cc1,,CCOCC,CN(C)C=O,[H-].[Na+],,test
US20160122342A1,C=CC(CO)Cc1cc(C)nc(OC)c1C#N>>C=CC(CO)Cc1cc(C)nc(OC)c1CN,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100144722A1,Cc1noc(C)c1-c1cc(Cl)nc(Cl)n1.NC1CCCC1>>Cc1noc(C)c1-c1cc(NC2CCCC2)nc(Cl)n1,,CO,,CCN(C(C)C)C(C)C,,test
US06346626B1,C1COCCO1.O=C(Oc1ccc2oc(C34CC5CC(CC(C5)C3)C4)cc(=O)c2c1)C12CC3CC(CC(C3)C1)C2>>O=c1cc(C=Cc2ccccc2)oc2ccc(O)cc12,,C1COCCO1,,[K+].[OH-],,test
US20100311693A1,CNS(C)(=O)=O.O=[N+]([O-])c1ccccc1CCl>>CN(Cc1ccccc1[N+](=O)[O-])S(C)(=O)=O,,O,,O=C([O-])[O-].[K+].[K+],,test
US04642308,Nc1ccc2ccc(Oc3ccccc3)nc2n1.O=C(O)c1ccsc1>>O=C(Nc1ccc2ccc(Oc3ccccc3)nc2n1)c1ccsc1,,O,,CC#N,,test
US04055595,COC(=O)C(C)(OCc1ccc(-c2ccc(Cl)cc2)cc1)C(F)(F)F>>CC(OCc1ccc(-c2ccc(Cl)cc2)cc1)(C(=O)O)C(F)(F)F,,O,,CO,[K+].[OH-],test
US20120264737A1,CI.COC(=O)c1cc(C(N)=S)c(C2CCC2)cc1C>>COC(=O)c1cc(C(=N)SC)c(C2CCC2)cc1C,,C1CCOC1,,,,test
US20040204586A1,CCOC(=O)CC(=O)OCC.Cc1ccc2c(c1)c(=O)oc(=O)n2C.Cl>>CCOC(=O)c1c(O)c2cc(Cl)ccc2n(C)c1=O,,CC(=O)N(C)C,,[H][H],[H-].[Na+],test
US20040044203A1,Cc1cc(-n2ccnc2)cc([N+](=O)[O-])c1N>>Cc1cc(-n2ccnc2)cc(N)c1N,[Pd],O,,,,test
US20050245503A1,NNc1ncc(C(=O)O)cc1Cl.S=C=N[C@H]1c2ccccc2CC[C@H]1c1ccccc1>>O=C(O)c1cnc(NNC(=S)N[C@H]2c3ccccc3CC[C@H]2c2ccccc2)c(Cl)c1,,CC(=O)N(C)C,,,,test
US04721797,COCC(=O)N(c1c(C)cccc1C)C1CCOC1=O.ClCl>>COCC(=O)N(c1c(C)ccc(Cl)c1C)C1CCOC1=O,Cl[Fe](Cl)Cl,O=CO,,,,test
US20070225324A1,CC(=O)OCCn1ccc2c(NC(=O)Cc3ccc(F)c(C(F)(F)F)c3)c(Cl)ccc2c1=O>>O=C(Cc1ccc(F)c(C(F)(F)F)c1)Nc1c(Cl)ccc2c(=O)n(CCO)ccc12,O,CO,,O=C([O-])[O-].[K+].[K+],,test
US20040157841A1,COCCOCCOc1ccc2sc(C(=O)Nc3ccccc3NC(=O)OC(C)(C)C)cc2c1>>COCCOCCOc1ccc2sc(C(=O)Nc3ccccc3N)cc2c1,,O=C(O)C(F)(F)F,,O=C([O-])O.[Na+],,test
US20040019051A1,O=c1[nH]cncc1OCC(Br)CBr>>BrCC1COc2cncnc2O1,,CCO,,O=C([O-])O.[Na+],,test
US20040236109A1,CC(=O)N1c2cc(C)c(N)cc2C(C)=CC1(C)C.c1ccccc1>>CC(=O)N1c2cc(C)c(N)cc2C(C)(c2ccccc2)CC1(C)C,,c1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US06448270B1,C#CCCS(C)(=O)=O.OC1(Cc2ccccc2)CCNCC1>>C#CCCN1CCC(O)(Cc2ccccc2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20030162972A1,O=C(CCc1cccnc1)NCCCCC1CCNCC1.O=C=Nc1cccc2ccccc12>>O=C(CCc1cccnc1)NCCCCC1CCN(C(=O)Nc2cccc3ccccc23)CC1,,C1CCOC1,,,,test
US20090326074A1,C=C(CCNC(=O)OC(C)(C)C)c1cccc(OCC2CCCCC2)c1.OO>>CC(C)(C)OC(=O)NCCC(CO)c1cccc(OCC2CCCCC2)c1,,C1CCOC1,,[Na+].[OH-],,test
US20160151509A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)[C@@H](CCCO)C(=O)OC1CCCC1.CC(C)(C)[Si](C)(C)Cl>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)[C@@H](CCCO[Si](C)(C)C(C)(C)C)C(=O)OC1CCCC1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20050154042A1,CC(C)n1c(C=O)c(-c2ccc(F)cc2)c(-c2ccccc2)c1C(=O)N(C)C>>CC(C)n1c(CO)c(-c2ccc(F)cc2)c(-c2ccccc2)c1C(=O)N(C)C,,C1CCOC1,CO,[BH4-].[Na+],,test
US04670040,CC(Br)C(=O)Cl.CCOP(=O)(CO)OCC>>CCOP(=O)(COC(=O)C(C)Br)OCC,,ClCCl,,CCN(CC)CC,,test
US20120022043A1,Cc1ccc(C)c(-c2n[nH]cc2N)c1.O=C(Cl)c1cnn2ccc(Cl)nc12>>Cc1ccc(C)c(-c2n[nH]cc2NC(=O)c2cnn3ccc(Cl)nc23)c1,,ClCCl,,CCN(CC)CC,,test
US20020040157A1,CNC(=S)Nc1cccc(C(=O)O)c1>>CNc1nc2cccc(C(=O)O)c2s1,,CC(=O)O,,BrBr,,test
US20090324581A1,N#CCc1cc(OCc2ccccc2)c(F)cc1[N+](=O)[O-]>>Fc1cc2[nH]ccc2cc1OCc1ccccc1,O=[Pt]=O,CCO,,,,test
US03950353,Clc1nc[nH]n1.NCCCN>>NCCCNc1nc[nH]n1,,CCO,,C,C[O-].[Na+],test
US20070004786A1,C#Cc1cccc(Br)c1.FC(F)(F)Cn1cc(I)cn1>>FC(F)(F)Cn1cc(C#Cc2cccc(Br)c2)cn1,I[Cu]I,CC#N,CCN(CC)CC,,,test
US20080119407A1,CCC(CC)(C(=O)Nc1cc(C(=O)OC)ccc1O)c1ccc(OCc2ccccc2)c(C)c1>>CCC(CC)(c1ccc(OCc2ccccc2)c(C)c1)c1nc2cc(C(=O)OC)ccc2o1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20090093454A1,CN1CCCNCC1.Fc1cccc2nc(CN3CCC[C@H]4CCc5cccnc5[C@H]43)cn12>>CN1CCCN(c2cccc3nc(CN4CCC[C@H]5CCc6cccnc6[C@H]54)cn23)CC1,,CN1CCCC1=O,,O,,test
US20140303149A1,Nc1cc(Cl)ccc1OC1CCC(O)CC1.O=C(O)c1cnn2cnccc12>>O=C(Nc1cc(Cl)ccc1OC1CCC(O)CC1)c1cnn2cccnc12,,CC#N,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060069110A1,CN(c1ccnc(F)n1)c1ccnc(-c2ccccc2)n1.C[C@H](N)c1ccc(CCNC(=O)OCc2ccccc2)cc1>>C[C@H](Nc1nccc(N(C)c2ccnc(-c3ccccc3)n2)n1)c1ccc(CCNC(=O)OCc2ccccc2)cc1,,C1COCCO1,,,,test
US20150011773A1,BrCc1ccc(OCc2ccccc2)cn1.CC(C)(C)OC(=O)CC[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H](C[C@H](Cc1ccc(OCc2ccccc2)cn1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US05053430,CCNC1CCc2ccc(NC(C)=O)cc2C1.Cl>>CCNC1CCc2ccc(N)cc2C1.Cl,,Cl,,,,test
US20150315197A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.Fc1cc(F)c(C(F)(F)F)c(Br)c1>>CC(C)(C)OC(=O)N1CC=C(c2cc(F)cc(F)c2C(F)(F)F)CC1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US04744812,COC(=O)CBr.OCc1cccc(Oc2ccc(C(F)(F)F)cc2Cl)c1>>COC(=O)COCc1cccc(Oc2ccc(C(F)(F)F)cc2Cl)c1,,C1CCOC1,,[H-].[Na+],,test
US20050245532A1,CC(C(=O)NC1C2CC3CC(C2)CC1C3)N1CCN(C(=O)OC(C)(C)C)CC1.Cl>>CC(C(=O)NC1C2CC3CC(C2)CC1C3)N1CCNCC1.Cl,,C1COCCO1,,,,test
US20050020596A1,CN(C)CCn1c(=O)[nH]c2cccnc21.O=S(=O)(Cl)c1cccc(F)c1>>CN(C)CCn1c(=O)n(S(=O)(=O)c2cccc(F)c2)c2cccnc21,CN(C)c1ccncc1,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20050148769A1,CC(=O)OCC(=O)CCl.CCOC(=O)CNS(=O)(=O)c1ccccc1[N+](=O)[O-]>>CCOC(=O)CN(CC(=O)COC(C)=O)S(=O)(=O)c1ccccc1[N+](=O)[O-],,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20090093483A1,CC(C)(C)OC(=O)CNC(=O)C1=C(O)c2cc(Br)ccc2C(C)(C)C1=O>>CC1(C)C(=O)C(C(=O)NCC(=O)O)=C(O)c2cc(Br)ccc21,,O=C(O)C(F)(F)F,,,,test
US20160235716A1,NCc1ccccc1.O=C(C1CC1)C1CC1>>c1ccc(CNC(C2CC2)C2CC2)cc1,,ClCCCl,,,,test
US20050026963A1,CCO.CCOC(C)=O.NNc1ccccn1>>c1ccc(-n2cccn2)nc1,,CCOC(C)=O,O,Cl,O=C([O-])O.[Na+],test
US20100060155A1,NNC(=O)c1ccc(I)cc1.O=C(Cl)c1ccccc1>>O=C(NNC(=O)c1ccc(I)cc1)c1ccccc1,,O,,CN1CCCC1=O,,test
US04431822,Nc1cc(O)c(Cl)cc1F.O=C1OC(=O)C2=C1CCCC2>>O=C1C2=C(CCCC2)C(=O)N1c1cc(O)c(Cl)cc1F,,CC(=O)O,,,,test
US20120289493A1,O=c1c2cc(-c3ccc(OC(F)(F)F)cc3)ccc2cnn1Cc1cccnc1Br.OB(O)C1CC1>>O=c1c2cc(-c3ccc(OC(F)(F)F)cc3)ccc2cnn1Cc1cccnc1C1CC1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20150166564A1,COCCN1C[C@@H](N=[N+]=[N-])[C@H](O)C1>>COCCN1C[C@@H](O)[C@H](N)C1,[Pd],CO,,,,test
US20140302523A1,CCOC(=O)COc1ccc(C23CC4CC(CC(C4)C2)C3)cc1>>O=C(O)COc1ccc(C23CC4CC(CC(C4)C2)C3)cc1,,C1CCOC1,O,[Li]O,,test
US20090088425A1,Cc1cc(C(O)(C(C)c2ccc(OCC(=O)OC(C)(C)C)cc2Cl)C(F)(F)F)ccn1>>Cc1cc(C(O)(C(C)c2ccc(OCC(=O)O)cc2Cl)C(F)(F)F)ccn1,,ClCCl,O,O=C(O)C(F)(F)F,,test
US04447260,CC1(C(=O)Cl)CC1.Nc1ccc(OC(F)F)c(F)c1>>CC1(C(=O)Nc2ccc(OC(F)F)c(F)c2)CC1,,ClCCl,,CCN(CC)CC,O,test
US20160145247A1,CC1(COc2cc(Br)cc(COc3ccccc3CC(=O)OC(C)(C)C)c2)CC1.C[C@@H](NC(=O)OC(C)(C)C)c1cccc(-c2cc(O)cc(COc3ccccc3CC(=O)OC(C)(C)C)c2)c1F>>C[C@@H](NC(=O)OC(C)(C)C)c1cccc(-c2cc(COc3ccccc3CC(=O)OC(C)(C)C)cc(OCC3(C)CC3)c2)c1F,,CN(C)C=O,,ClCCl,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US04066772,CC(C)n1c(=O)n(CCCCl)c2ccccc21.OC1(c2ccc(F)cc2)CCNCC1>>O=c1[nH]c2ccccc2n1CCCN1CCC(O)(c2ccc(F)cc2)CC1,,CC(=O)CC(C)C,O,[Na+].[OH-],,test
US20160107997A1,CN(C)CCN(Cc1ccccc1)C(=O)CNc1cccc2c1CCN(C(=O)OC(C)(C)C)C2.Cl.ClCCl>>CN(C)CCN(Cc1ccccc1)C(=O)CNc1cccc2c1CCNC2.Cl.Cl,,C1COCCO1,ClCCl,,,test
US20080261941A1,CC(=C1CCN(C(=O)OC(C)(C)C)CC1)c1cccc(Oc2ccc(C(F)(F)F)cn2)c1.O=C(O)C(F)(F)F>>CC(=C1CCNCC1)c1cccc(Oc2ccc(C(F)(F)F)cn2)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US05212320,CC(C)Cc1cccc(C(O)c2cccc(CC(C)C)c2)c1.O=C(Cl)C(=O)Cl>>CC(C)Cc1cccc(C(Cl)c2cccc(CC(C)C)c2)c1,,ClCCl,,,,test
US20070259907A1,CCCc1nc2c(N)nc3cc(Br)ccc3c2s1.O=C(c1cccc(B(O)O)c1)N1CCCC1>>CCCc1nc2c(N)nc3cc(-c4cccc(C(=O)N5CCCC5)c4)ccc3c2s1,,CCOCC,,,,test
US20050054662A1,O=c1[nH]cnc2cc(F)cc(F)c12.OCc1ccccc1>>O=c1[nH]cnc2cc(F)cc(OCc3ccccc3)c12,,CN(C)C=O,,[H-].[Na+],,test
US07745589B1,CC(C)=CCCC(C)=CCCC(C)=CCBr.COC(=O)[C@@H](N)CS>>COC(=O)C(N)CSCC=C(C)CCC=C(C)CCC=C(C)C,,CO,N,,,test
US20100249119A1,CN(c1ccc(F)c(NC(=O)OC(C)(C)C)c1)c1ncc([N+](=O)[O-])c(SC#N)n1>>CN(c1ccc(F)c(NC(=O)OC(C)(C)C)c1)c1ncc2nc(N)sc2n1,,CC(=O)O,,,,test
US20030069297A1,Cc1[nH]c(C=O)c(C)c1C(=O)NCCN1CCCC1.O=C1Cc2c(cccc2-c2ccc(F)cc2)N1>>Cc1[nH]c(C=C2C(=O)Nc3cccc(-c4ccc(F)cc4)c32)c(C)c1C(=O)NCCN1CCCC1,C1CCNCC1,CCO,,,,test
US20090082379A1,CC(C)(C)c1ccc(N2C(=O)N(Cc3ccn4oc(=S)nc4c3)C(C)(C)C2=O)cc1.NC1CCC1>>CC(C)(C)c1ccc(N2C(=O)N(Cc3ccnc(NC(=O)NC4CCC4)c3)C(C)(C)C2=O)cc1,,C1COCCO1,,,,test
US20010039281A1,CCC(C)N[C@@H](Cc1ccccc1-n1ncn(-c2ccc(N3CCN(c4ccc(OCC5COC(Cn6cncn6)(c6ccc(F)cc6F)O5)cc4)CC3)cc2)c1=O)C(=O)O.O=C(O)/C=C\C(=O)O>>CCC(C)N[C@@H](Cc1ccccc1-n1ncn(-c2ccc(N3CCN(c4ccc(OCC5COC(Cn6cncn6)(c6ccc(F)cc6F)O5)cc4)CC3)cc2)c1=O)C(=O)O.O=C(O)/C=C\C(=O)O,,CC(C)=O,,,,test
US20090247559A1,CN1CCC[C@H]1C(=O)Nc1c(C(N)=O)oc2ccc(Br)cc12.Cl>>CN1CCC[C@H]1c1nc2c(oc3ccc(Br)cc32)c(=O)[nH]1.Cl,,CCO,,[Na+].[OH-],,test
US20120095002A1,CCNC(C)C.O=C(NC1CCCC1)c1onc(-c2ccc(C(F)(F)F)c(F)c2)c1CCl>>CCN(Cc1c(-c2ccc(C(F)(F)F)c(F)c2)noc1C(=O)NC1CCCC1)C(C)C,,CC#N,,CCN(C(C)C)C(C)C,,test
US20050014749A1,Cc1cc(C)c(S(=O)(=O)N2CC(C)(C)NC(=O)C2CC(=O)O)c(C)c1.N[C@@H]1CCc2ccccc21>>Cc1cc(C)c(S(=O)(=O)N2CC(C)(C)NC(=O)C2CC(=O)NC2CCc3ccccc32)c(C)c1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040082571A1,CCOC(=O)c1c(N)n[nH]c1C.O=C(CCl)N1CCN(c2ccc(F)cc2)CC1>>CCOC(=O)c1c(N)nn(CC(=O)N2CCN(c3ccc(F)cc3)CC2)c1C,,CCCCCC,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20120142705A1,COC(=O)C(Br)CC1CCCC1.O=C1Nc2cc(Br)ccc2C1=O>>COC(=O)C(CC1CCCC1)N1C(=O)C(=O)c2ccc(Br)cc21,,CN(C)C=O,O,[H-].[Na+],,test
US20120010191A1,O=C1NCCn2c1nc1ccccc12>>O=C1NCCn2c1nc1c2CCCC1,[Pd],CC(=O)O,,,,test
US20100210651A1,Cc1cc(O)no1.Cc1onc(-c2ccccc2)c1CO>>Cc1cc(OCc2c(-c3ccccc3)noc2C)no1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04282242,COC(=O)c1cc[nH]c1.ClSc1ccc(Cl)cc1Cl>>COC(=O)c1c[nH]c(Sc2ccc(Cl)cc2Cl)c1,,ClCCl,,,,test
US20100197683A1,CCCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OC(C)C(C)(C)O)CC2)c2nc(C)nn12.O=C([O-])O.[NH3+]O>>CCCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n([C@@H]2CC[C@@H](OC(C)C(C)(C)O)CC2)c2nc(C)nn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20160007601A1,COC(=O)C1CN1C(=O)OC(C)(C)C.OC[C@H](Cc1ccccc1)[C@H](CO)Cc1ccccc1>>COC(=O)[C@H](COC[C@H](Cc1ccccc1)[C@H](CO)Cc1ccccc1)NC(=O)OC(C)(C)C,,ClCCl,,CCOCC,FB(F)F,test
US05106871,COC(=O)COc1cc(OC)cc(OC)c1C(=O)CCc1ccc(OC)cc1>>COc1ccc(CCC(=O)c2c(OC)cc(OC)cc2OCC(=O)O)cc1,,CO,,Cl,[K+].[OH-],test
US04077980,CC(C)NC(C)C.CCCCCC.CCOC(=O)CCC(CSCC(CCC(=O)OCC)(OCC)OCC)(OCC)OCC>>CCOC(=O)C(CC#CCCCC#N)SCC(OCC)OCC,,C1CCOC1,,O,[Li]CCCC,test
US20080021032A1,Cc1ccc(Cn2ccc(N)n2)cc1.Cn1ccc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(C)(=O)=O)c(Cl)c2)n1>>Cc1ccc(Cn2ccc(NC(=O)[C@H](CC3CCCC3)c3ccc(S(C)(=O)=O)c(Cl)c3)n2)cc1,,ClCCl,,Cc1cccc(C)n1,O=C(Cl)C(=O)Cl,test
US20080269244A1,CS(=O)(=O)O.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(N3CCN(C(=O)CC4CCCC4)CC3)nc2)cc1>>CS(=O)(=O)O.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(N3CCN(C(=O)CC4CCCC4)CC3)nc2)cc1,,CO,ClCCl,N#N,,test
US20090022670A1,CC(C)(C)OC(=O)N1CCCC[C@H]1Cc1cn2cccc(F)c2n1>>Fc1cccn2cc(C[C@@H]3CCCCN3)nc12,,ClCCl,,C1COCCO1,Cl,test
US04173545,BrBr.CCCCCCCCOc1ccc(C(=O)O)cc1>>CCCCCCCCOc1ccc(C(=O)O)cc1Br,,O,,,,test
US20140228368A1,CCOC(=O)C(=O)NNC(=O)CNC(=O)OC(C)(C)C.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)c1nnc(CNC(=O)OC(C)(C)C)s1,,C1CCOC1,,,,test
US20150299183A1,COc1c(C#N)ccc(C)c1[N+](=O)[O-]>>COc1c(N)cccc1C#N,[Zn],C1CCOC1,,CO,[Cl-].[NH4+],test
US04547514,CCN(CC)CCCN.O=C(Cl)N1CCC(Oc2cccc(Cl)c2)C1>>CCN(CC)CCCNC(=O)N1CCC(Oc2cccc(Cl)c2)C1,,ClC(Cl)Cl,,O,O=C([O-])[O-].[Na+].[Na+],test
US04247700,C=O.CCOC(=O)C1CCNCC1.N#CCC(=O)O>>C=C(C#N)CN1CCC(C(=O)OCC)CC1,,C1COCCO1,O,O=C=O,,test
US20080058369A1,CCc1nc2c(cnn2CC)c(NC2CCN(C(N)=O)CC2)c1CN.O=C(Cl)c1ccc(CCCCOCCCCBr)cc1>>CCc1nc2c(cnn2CC)c(NC2CCN(C(N)=O)CC2)c1CNC(=O)c1ccc(CCCCOCCCCBr)cc1,,ClCCl,,CCN(CC)CC,O,test
US20070254940A1,O=[N+]([O-])c1ccc2c(C3=CN4CCC3CC4)c[nH]c2c1>>Nc1ccc2c(C3=CN4CCC3CC4)c[nH]c2c1,[Ni],CO,,NN,O,test
US20140371449A1,CC1(C)O[C@H]2[C@H](NC(c3ccccc3)(c3ccccc3)c3ccccc3)C[C@H](O)[C@H]2O1.Cc1ccc(S(=O)(=O)OCCOC(C)(C)C)cc1>>CC(C)(C)OCCO[C@H]1C[C@@H](NC(c2ccccc2)(c2ccccc2)c2ccccc2)[C@@H]2OC(C)(C)O[C@H]12,,CN(C)C=O,,[H-].[Na+],,test
US20130059835A1,COc1c(C(C)Cl)cc(Cl)c(C)c1-c1ccnc(C#N)c1.Nc1ncnc2[nH]ncc12>>COc1c(C(C)n2ncc3c(N)ncnc32)cc(Cl)c(C)c1-c1ccnc(C#N)c1,,CN(C)C=O,,O,[H-].[Na+],test
US09067898B1,BrCc1ccccc1.O=C1CCc2c(Br)ccc(O)c21>>O=C1CCc2c(Br)ccc(OCc3ccccc3)c21,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080139631A1,BrCc1nnc(C2CC2)s1.CCCc1cc2c(C(F)(F)F)c(C#N)ccc2[nH]1>>CCCc1cc2c(C(F)(F)F)c(C#N)ccc2n1Cc1nnc(C2CC2)s1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06307051B1,CC(C)=C1Oc2cccc(O)c2C1=O.ClCc1ccc(CCl)cc1>>CC(C)=C1Oc2cccc(OCc3ccc(CCl)cc3)c2C1=O,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20020156081A1,COc1cc(-c2nn(-c3ccc([N+](=O)[O-])cc3)c3ncnc(N)c23)ccc1NC(=O)OC(C)(C)C>>COc1cc(-c2nn(-c3ccc([N+](=O)[O-])cc3)c3ncnc(N)c23)ccc1N,,ClCCl,,O=C(O)C(F)(F)F,,test
US05780642,CCOC(=O)CC(=O)OCC.ClCc1nccn1Cc1ccccc1>>CCOC(=O)C(Cc1nccn1Cc1ccccc1)C(=O)OCC,,CCO,,Cl,[Na],test
US03947434,CCBr.COc1ccc(O)c([N+](=O)[O-])c1>>CCOc1ccc(OC)cc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140005213A1,CC(C)(C)OC(=O)N1C[C@H](O)[C@@H](O)C1.COc1ccc(C(Cl)(c2ccccc2)c2ccc(OC)cc2)cc1>>COc1ccc(C(O[C@H]2CN(C(=O)OC(C)(C)C)C[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1,,c1ccncc1,,,,test
US20050182040A1,COc1cc(N)c(C)cc1[N+](=O)[O-].O=C1OC(=O)c2ccccc21>>COc1cc(N2C(=O)c3ccccc3C2=O)c(C)cc1[N+](=O)[O-],,CC(=O)O,,,,test
US20030069273A1,NNCc1ccncc1.O=c1nc(-c2ccccc2O)oc2ccccc12>>Oc1ccccc1-c1nc(-c2ccccc2O)n(Cc2ccncc2)n1,,CCO,,CCN(CC)CC,Cl,test
US20100010053A1,CC(C)Oc1ccc(-c2nc(-c3cccc4cc[nH]c34)no2)cc1Cl.COC(=O)OC>>CC(C)Oc1ccc(-c2nc(-c3cccc4ccn(C)c34)no2)cc1Cl,,CN(C)C=O,,C1CN2CCN1CC2,,test
US20040186103A1,CC(C)[C@H]1COC(=O)N1C(=O)[C@@H](C)c1ccc(Cl)cc1.OO>>C[C@H](C(=O)O)c1ccc(Cl)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20150141402A1,C=CC(=O)Cl.CC(C)n1cnc2c(Nc3cnn(C)c3)nc(C3CCCNC3)nc21>>C=CC(=O)N1CCCC(c2nc(Nc3cnn(C)c3)c3ncn(C(C)C)c3n2)C1,,CCOC(C)=O,,O=C([O-])O.[Na+],,test
US20030229051A1,O=S(=O)(CCO)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1>>C=CS(=O)(=O)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US06627651B1,CCOCCOc1c(C)cc(Oc2ccc3c(c2)C=C(C(=O)OC)CCS3(=O)=O)cc1C>>CCOCCOc1c(C)cc(Oc2ccc3c(c2)C=C(C(=O)O)CCS3(=O)=O)cc1C,,CO,,C1CCOC1,O=C([O-])[O-].[K+].[K+],test
US05011932,CCCC(=O)NN=C(C)c1ccncc1.O=C(O)c1ccc2ccccc2c1O>>CCCC(=O)NN=C(C)c1ccncc1.O=C(O)c1ccc2ccccc2c1O,,CCO,,,,test
US20090137601A1,COC(=O)[C@H](Cc1ccc(C2=CCNCC2)cc1)NC(=O)c1c(Cl)cccc1Cl.O=S(=O)(Cl)c1ccccc1>>O=C(N[C@@H](Cc1ccc(C2=CCN(S(=O)(=O)c3ccccc3)CC2)cc1)C(=O)O)c1c(Cl)cccc1Cl,,c1ccncc1,,,,test
US04956474,Cc1cc(=O)n2nc(SCC3=C(C(=O)OC(c4ccccc4)c4ccccc4)N4C(=O)[C@@H](NC(=O)/C(=N\OC(=O)c5cc(OC(=O)CCl)c(OC(=O)CCl)cc5C)c5csc(NC(c6ccccc6)(c6ccccc6)c6ccccc6)n5)[C@H]4SC3)sc2n1>>Cc1cc(=O)n2nc(SCC3=C(C(=O)O)N4C(=O)[C@@H](NC(=O)/C(=N\OC(=O)c5cc(OC(=O)CCl)c(OC(=O)CCl)cc5C)c5csc(N)n5)[C@H]4SC3)sc2n1,,CC(Cl)Cl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US04282246,O=C(O)c1coc(Br)c1.Sc1cccc(Cl)c1>>O=C(O)c1coc(Sc2cccc(Cl)c2)c1,,CN(C)C=O,,,,test
US20130310377A1,FC(F)(F)c1cc(C2CC2)[nH]n1.O=[N+]([O-])c1cc(F)c(F)c(F)c1>>O=[N+]([O-])c1cc(F)c(-n2nc(C(F)(F)F)cc2C2CC2)c(F)c1,,C1CCOC1,,[H-].[Na+],,test
US20120197014A1,COC(=O)Cc1c[nH]c2ccc(Br)cc12>>OCCc1c[nH]c2ccc(Br)cc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090215758A1,C1CSCCN1.N.S=C(n1ccnc1)n1ccnc1>>NC(=S)N1CCSCC1,,C1CCOC1,CO,,,test
US20080125581A1,COCCOCCOCC(NC(=O)OC(C)(C)C)C(=O)O>>COCCOCCOC[C@H](NC(=O)OC(C)(C)C)C(=O)O,,ClC(Cl)Cl,,,,test
US20020004511A1,COC(=O)Cl.Cn1ccnc1-c1cc2nccc(Cl)c2s1>>COC(=O)c1cnc(-c2cc3nccc(Cl)c3s2)n1C,,C1CCOC1,,[Li]CCCC,,test
US20100029650A1,CC(C)c1noc(N2CCC(C(C)Oc3cnc(-c4ccc(S(C)(=O)=O)cc4)cn3)CC2)n1>>CC(C)c1noc(N2CCC([C@H](C)Oc3cnc(-c4ccc(S(C)(=O)=O)cc4)cn3)CC2)n1,,CO,,O=C=O,,test
US20050090533A1,CS(=O)(=O)Cl.Cc1cc(F)ccc1-c1cc(N2CC[C@@H](N)C2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1cc(F)ccc1-c1cc(N2CC[C@@H](NS(C)(=O)=O)C2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110237628A1,N#Cc1ccc(OCC(c2c3c(nn2-c2ccc(Cl)cc2)CCCCC3)C2CCCCC2)c(F)c1.[N-]=[N+]=[N-]>>Fc1cc(-c2nnn[nH]2)ccc1OCC(c1c2c(nn1-c1ccc(Cl)cc1)CCCCC2)C1CCCCC1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20080188528A1,CI.O=C(O)c1cccnc1O>>Cn1cccc(C(=O)O)c1=O,,CO,,[K+].[OH-],,test
US20090186886A1,Nc1nc2cc3c(cc2[n+]([O-])n1)CCC3>>[O-][n+]1ncnc2cc3c(cc21)CCC3,,CN(C)C=O,,CC(C)(C)ON=O,,test
US20080207654A1,CCCc1nc(CC)n(-c2ccc(O)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.OC1CCC(F)(F)CC1>>CCCc1nc(CC)n(-c2ccc(OC3CCC(F)(F)CC3)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110070190A1,Nc1ccc(-c2cc3c(s2)c(=O)ncn3Cc2ccc(Cl)cc2)cc1Cl.O=C1CCCO1>>O=C(CCCO)Nc1ccc(-c2cc3c(s2)c(=O)ncn3Cc2ccc(Cl)cc2)cc1Cl,,ClCCl,,,,test
US20110190297A1,NC(=O)C1CCN(c2c(Cl)cncc2Cl)CC1.OB(O)c1ccc(F)cc1>>NC(=O)C1CCN(c2c(Cl)cncc2-c2ccc(F)cc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US05225596,CCCN(CCC)C1CCc2cccc(Br)c2C1.CSC>>CCCN(CCC)C1CCc2cccc(SC)c2C1,,CCOCC,,O,,test
US04727081,CN=C=O.NNC(=S)NCCCOc1cccc(CN2CCCCC2)c1>>CNC(=O)NNC(=S)NCCCOc1cccc(CN2CCCCC2)c1,,C1CCOC1,,CCOCC,,test
US20080221110A1,CC(C)OB(OC(C)C)OC(C)C.COc1ccc2cccc(Br)c2n1>>COc1ccc2cccc(B(O)O)c2n1,,C1CCOC1,Cc1ccccc1,[Li]CCCC,,test
US20020040020A1,CC(C)(C)OC(=O)N1CCc2c(c(-c3ccc(C(F)(F)F)cc3)nn2CCCN2CCN(c3c(N)cccc3Cl)CC2)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCc2c(c(-c3ccc(C(F)(F)F)cc3)nn2CCCN2CCN(c3c(Cl)cccc3NS(C)(=O)=O)CC2)C1,,CCOC(C)=O,ClCCl,CCN(CC)CC,O=C([O-])O.[Na+],test
US20100311966A1,CC(C)(C)OC(=O)NC1CCN(C(=O)OCc2ccccc2)CC1.CCCI>>CCCN(C(=O)OC(C)(C)C)C1CCN(C(=O)OCc2ccccc2)CC1,,C1CCOC1,,O,[H-].[Na+],test
US20090131455A1,Cc1cc2c(=O)[nH]c(Cn3cc(C=O)c(C(F)(F)F)n3)nc2s1>>Cc1cc2c(=O)[nH]c(Cn3cc(CO)c(C(F)(F)F)n3)nc2s1,,ClCCl,,CO,[BH4-].[Na+],test
US05623049,COC(=O)[C@@H]1C[C@H](O)CN1C(=O)OCc1ccccc1.CS(=O)(=O)Cl>>COC(=O)[C@@H]1C[C@H](OS(C)(=O)=O)CN1C(=O)OCc1ccccc1,,c1ccncc1,,,,test
US20060258860A1,COC(=O)c1nc([C@@H]2CC(F)(F)CN2C(=O)OCc2ccccc2)n(C)c(=O)c1OC(=O)c1ccccc1.NCc1ccc(F)cc1>>Cn1c([C@@H]2CC(F)(F)CN2C(=O)OCc2ccccc2)nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O,,CO,,,,test
US20060264429A1,C1CNCCN1.Cc1ccc2c(F)cc(F)cc2n1>>Cc1ccc2c(N3CCNCC3)cc(F)cc2n1,,CS(C)=O,,,,test
US07758931B2,Cl.Nc1c(F)cccc1F>>Fc1cccc(F)c1Cl,,O,,O=N[O-].[Na+],,test
US20070254957A1,C=C(C)CC(C(=O)OC)c1cc(OCc2ccccc2)cc(OCc2ccccc2)c1>>C=C(C)CC(C(=O)OC)c1cc(O)cc(OCc2ccccc2)c1,[Pd],CO,,[Na+].[OH-],,test
US20110257174A1,CC(=O)c1cccc([N+](=O)[O-])c1O.O=C(Cl)c1cccnc1C(F)(F)F>>O=C(CC(=O)c1cccc([N+](=O)[O-])c1O)c1cccnc1C(F)(F)F,,c1ccncc1,,C1CCC2=NCCCN2CC1,Cl,test
US05144045,CCCCCCCCCCCCCCCCBr.CCOC(=O)C(=O)OCC>>CCCCCCCCCCCCCCCCC(=O)C(=O)OCC,,C1CCOC1,,Cl,[Mg],test
US20080280911A1,CCSc1cc(C)c2nnc(C(N)=O)c(Cl)c2c1.Cl.Nc1cncc(Cl)c1>>CCSc1cc(C)c2nnc(C(N)=O)c(Nc3cncc(Cl)c3)c2c1.Cl,,CC#N,,Cl,,test
US20130096113A1,CS(=O)c1nc2ccc(Cn3cnc4ccc(Br)nc43)cc2s1.N[C@@H]1c2ccccc2C[C@H]1O>>O[C@@H]1Cc2ccccc2[C@H]1Nc1nc2ccc(Cn3cnc4ccc(Br)nc43)cc2s1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,,test
US04476308,CC(=O)OC1CCN(CC(=O)O)C1=O.CC1CCCC(C)N1CCN>>CC(=O)OC1CCN(CC(=O)NCCN2[C@@H](C)CCC[C@H]2C)C1=O,,C1CCOC1,,,,test
US05243042,CC(=O)OC[C@H]1O[C@@H](n2cnc(C(=O)OC(c3ccccc3)c3ccccc3)c2N)[C@H](OC(C)=O)[C@@H]1OC(C)=O.O=C(N=C=S)OCc1ccccc1>>CC(=O)OC[C@H]1O[C@@H](n2cnc(C(=O)OC(c3ccccc3)c3ccccc3)c2NC(=S)NC(=O)OCc2ccccc2)[C@H](OC(C)=O)[C@@H]1OC(C)=O,,ClCCl,,,,test
US20160272651A1,CCc1cc(Br)cc(C)c1NC(=O)NCCCl>>CCc1cc(Br)cc(C)c1N1CCNC1=O,,CN(C)C=O,,[H-].[Na+],,test
US20110053921A1,O=C1Nc2cnc(Cl)nc2N2CCOCC12.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>O=C1C2COCCN2c2nc(Cl)ncc2N1CC(F)(F)F,,CN(C)C=O,,O,[H-].[Na+],test
US20040181066A1,BrBr.CSc1nccc(C(C)=O)n1>>CSc1nccc(C(=O)CBr)n1,,Br,,,,test
US20090048326A1,CC(C)c1ccc(S(=O)(=O)Cl)cc1.CCC(=O)N1C[C@@H]2C[C@@H](c3ccc(N)cc3)[C@@H]2C1>>CCC(=O)N1C[C@@H]2C[C@@H](c3ccc(NS(=O)(=O)c4ccc(C(C)C)cc4)cc3)[C@@H]2C1,,C1CCOC1,,CCN(CC)CC,,test
US20070293515A1,CC(C)(C)OC(=O)N[C@H]1CCNC1.ClC(Cl)(Cl)c1nc(-c2ccccc2)no1>>CC(C)(C)OC(=O)N[C@H]1CCN(c2nc(-c3ccccc3)no2)C1,,CO,,,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Nc1cc(C2CCC2)n[nH]1>>COc1ccc2nc(Nc3cc(C4CCC4)n[nH]3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US06884868B1,BrCCCCCCCBr.Cc1cc(Br)cc(C)c1O>>Cc1cc(Br)cc(C)c1OCCCCCCCBr,,CN(C)C=O,ClCCl,O,O=C([O-])[O-].[K+].[K+],test
US20050137171A1,CC(C)(C)OC(=O)n1c(B(O)O)cc2ccccc21.COP(=O)(OC)c1ccc2c(c1)c(I)nn2C(=O)OC(C)(C)C>>COP(=O)(O)c1ccc2[nH]nc(-c3cc4ccccc4[nH]3)c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20040106795A1,CCCCOc1c(Cl)cc(CN(C=O)OCc2ccccc2)cc1Cl>>CCCCOc1c(Cl)cc(CN(O)C=O)cc1Cl,[Pd],CO,,,,test
US04316043,C=CC12CCC(=O)C=C1c1c(cc(OCC(=O)OC)c(Cl)c1Cl)C2>>C=CC12CCC(=O)C=C1c1c(cc(OCC(=O)O)c(Cl)c1Cl)C2,,CO,,[Na+].[OH-],,test
US20030096788A1,NC1CCOCC1.O[C@@H]1[C@@H](c2ccn[nH]2)O[C@@H](n2cnc3c(Cl)ncnc32)[C@@H]1O>>O[C@H]1[C@@H](c2ccn[nH]2)O[C@@H](n2cnc3c(NC4CCOCC4)ncnc32)[C@H]1O,,CC(C)O,,CCN(C(C)C)C(C)C,Cl,test
US04234588,CCOC(=O)C(C=O)C(C)c1cccnc1.NC(N)=S>>CC(c1cccnc1)c1c[nH]c(=S)[nH]c1=O,,CCO,,C,C[O-].[Na+],test
US20140296208A1,COc1cc(Nc2cc(Oc3ccc(NC(=O)OC(C)(C)C)c4ccccc34)ccn2)cc(C(=O)NCCN2CCOCC2)c1>>COc1cc(Nc2cc(Oc3ccc(N)c4ccccc34)ccn2)cc(C(=O)NCCN2CCOCC2)c1,,CC(C)O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20050107609A1,CSc1cc(Cl)ncn1.N#CCc1ccccc1>>CSc1cc(C(C#N)c2ccccc2)ncn1,,C1CCOC1,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US06204293B1,O=C(O)[C@@H](O)CC1CCCCC1>>OC[C@@H](O)CC1CCCCC1,,C1CCOC1,,B,,test
US20100029650A1,CC(C)(C)OC(=O)NCCNS(=O)(=O)c1ccc(Br)cc1.OB(O)c1ccc(O)cc1>>CC(C)(C)OC(=O)NCCNS(=O)(=O)c1ccc(-c2ccc(O)cc2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20100256097A1,COC(=O)C1(N)CCN(Cc2ccccc2)CC1>>NC1(CO)CCN(Cc2ccccc2)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070161695A1,C[C@@H](O[C@H]1CC[C@@H]2CN(C3=CC(=O)CC3=O)C[C@H]2[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[C@@H](O[C@H]1CC[C@@H]2CN(C3=CC(=O)CC3O)C[C@H]2[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,CO,,[BH4-].[Na+],,test
US20090105221A1,O=C(O)C(O)(c1ccc(F)cc1)C1CCCC1.OC1C2CCC1CN(Cc1ccccc1)C2>>O=C(OC1C2CCC1CN(Cc1ccccc1)C2)C(O)(c1ccc(F)cc1)C1CCCC1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,[H-].[Na+],test
US20120208827A1,COc1cccc(NC[C@@H]2CCN(C(=O)OC(C)(C)C)C2)c1[N+](=O)[O-].Cl>>COc1cccc(NC[C@@H]2CCNC2)c1[N+](=O)[O-].Cl,,CO,,,,test
US20100184815A1,CC(C)(C)OC(=O)C(C)(C)Oc1ccc(C(=O)O)cc1.CCCn1c(CO)nn(Cc2ccc(C)cc2)c1=O>>CCCn1c(COC(=O)c2ccc(OC(C)(C)C(=O)OC(C)(C)C)cc2)nn(Cc2ccc(C)cc2)c1=O,CN(C)c1ccncc1,CN(C)C=O,,ClCCCl,,test
US20110245249A1,COC(OC)c1cccc(N)c1.Clc1ncc(Cl)c(NC2CC2)n1>>O=Cc1cccc(Nc2ncc(Cl)c(NC3CC3)n2)c1,,C1COCCO1,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20090186879A1,CCOC(=O)CCCn1c(Nc2ccc(OC(F)(F)F)cc2Br)nc2c(Cl)ccc(C(CC)CC)c21>>CCC(CC)c1ccc(Cl)c2nc(Nc3ccc(OC(F)(F)F)cc3Br)n(CCCCO)c12,,C1CCOC1,,[BH4-].[Li+],,test
US20110237565A1,CC(C)(C)OC(=O)N1CCN(c2ncc(CO)n3cnnc23)CC1>>CC(C)(C)OC(=O)N1CCN(c2ncc(C=O)n3cnnc23)CC1,O=[Mn]=O,ClCCl,,,,test
US20130053409A1,COc1cc(N2CCN(CC(=O)N(C)C)CC2)c([N+](=O)[O-])cc1Nc1ncc(Cl)c(-c2cnn3ccccc23)n1>>COc1cc(N2CCN(CC(=O)N(C)C)CC2)c(N)cc1Nc1ncc(Cl)c(-c2cnn3ccccc23)n1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20050096322A1,CCOP(=O)(Cc1nnc2ccc(N3CCCCCC3)nn12)OCC.O=Cc1ccccc1Br>>Brc1ccccc1/C=C/c1nnc2ccc(N3CCCCCC3)nn12,,C1CCOC1,,O,CC(C)(C)[O-].[K+],test
US20040254214A1,CCOc1cc([C@@H](CC(=O)OC)N2Cc3c(Cl)ccc(NC(=O)C4CC4)c3C2=O)ccc1OC>>CCOc1cc([C@@H](CC(=O)O)N2Cc3c(Cl)ccc(NC(=O)C4CC4)c3C2=O)ccc1OC,,C1CCOC1,,O,[Na+].[OH-],test
US20110136800A1,N.O=C(O)c1cccc2c1[C@H]1CCCN(C(=O)c3ccc4[nH]cnc4c3)[C@H]1CC2>>NC(=O)c1cccc2c1[C@H]1CCCN(C(=O)c3ccc4[nH]cnc4c3)[C@H]1CC2,,CO,ClCCl,,,test
US20130184292A1,C#Cc1nc(Br)cnc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.CC(C)(C)OC(=O)N(Cc1ccc(C(Cl)=NO)cc1)C1CCOCC1.ClCCl>>CN(Cc1ccc(-c2cc(-c3nc(Br)cnc3N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)on2)cc1)C(=O)OC(C)(C)C,,ClCCl,O,CCN(CC)CC,,test
US20110230459A1,CCOC(=O)C(CC#N)(c1ccc(Cl)cc1)c1ccc(Cl)cc1>>O=C1NCCC1(c1ccc(Cl)cc1)c1ccc(Cl)cc1,[Ni],CO,,N,O,test
US20140128360A1,BrCCBr.CS(=O)(=O)c1cc(O)cc(F)c1>>CS(=O)(=O)c1cc(F)cc(OCCBr)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20160152616A1,CC(C)=CCC[C@@H](C)CCBr.CC1(C)CCn2c(=O)c(=O)[nH]c3cccc1c32>>CC(C)=CCC[C@@H](C)CCn1c(=O)c(=O)n2c3c(cccc31)C(C)(C)CC2,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20060293343A1,CCN(CC)CC.CCN=C=NCCCN(C)C.CCc1c(C)nc(-c2ccc(Br)s2)nc1Nc1ccc(C(=O)O)cc1.CN(C)C=O.On1nnc2ccccc21>>CCc1c(C)nc(-c2ccc(Br)s2)nc1Nc1ccc(C(=O)NOC(C)(C)OC)cc1,CCN(CC)CC,,,Cl,O,test
US20120114600A1,COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(-c2ccc(-c3cc(Cl)c(N)cc3C(F)(F)F)cc2)c[nH]1)C(C)C.O=C(Cl)c1ccc(F)nc1>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(-c2ccc(-c3cc(Cl)c(NC(=O)c4ccc(F)nc4)cc3C(F)(F)F)cc2)c[nH]1)C(C)C,,ClCCl,,,,test
US06960662B2,CCn1c(=O)c(-c2cc(OC)cc(OC)c2)cc2cnc(S(C)=O)nc21.Cl.Nc1ccncc1>>CCn1c(=O)c(-c2cc(OC)cc(OC)c2)cc2cnc(-n3ccc(=N)cc3)nc21.Cl,,CC#N,CCO,,,test
US20160200708A1,CC(C)c1cc(Cl)ncn1.O=C1CCC(=O)N1Cl>>CC(C)(Cl)c1cc(Cl)ncn1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20120270867A1,COC(=O)c1cc(NC(=O)Cc2nc(N3CCOCC3)cc(=O)[nH]2)ccc1F>>O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1ccc(F)c(C(=O)O)c1,,CO,,[Na+].[OH-],,test
US20130214249A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Ic1ccc2c(c1)c1ccccc1n2-c1ccccc1>>CC1(C)OB(c2ccc3c(c2)c2ccccc2n3-c2ccccc2)OC1(C)C,,C1COCCO1,Cc1ccccc1,O,CC(=O)[O-].[K+],test
US20050222231A1,CCOC(=O)[C@H]1C2C1[C@](N[C@H](C)c1ccccc1)(C(=O)OCC)C[C@@H]2O.COCCN(CCOC)S(F)(F)F>>CCOC(=O)[C@H]1C2C1[C@](N[C@H](C)c1ccccc1)(C(=O)OCC)C[C@H]2F,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20150225389A1,CC(C)(C)[Si](c1ccccc1)(c1ccccc1)N1C(=O)C[C@H]1C(=O)OCc1ccccc1>>CC(C)(C)[Si](c1ccccc1)(c1ccccc1)N1C(=O)C[C@H]1CO,,CO,,[BH4-].[Na+],,test
US05102901,CC1CCc2cccc3c(C(=O)O)cn1c23.CNCc1ncn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c1C>>Cc1c(CNC(=O)c2cn3c4c(cccc24)CCC3C)ncn1C(c1ccccc1)(c1ccccc1)c1ccccc1,,CC#N,,,,test
US20150238558A1,CC(C)(C)OC(=O)N[C@H](C(=O)N1Cc2ccccc2C[C@H]1CO)C(C)(C)C>>CC(C)(C)[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1CO,,ClCCl,,Cl,,test
US20110054115A1,C=CC(=O)OCCC(=O)Cl.CC1CN1>>C=CC(=O)OCCC(=O)N1CC1C,,ClCCl,O,[Na+].[OH-],,test
US20110046110A1,CC(C)(C)OC(=O)Nc1cccc(CN2CCCC2)n1>>Nc1cccc(CN2CCCC2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040006099A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(C=O)cc2)C1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(O)cc2)C1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US04152319,C/C=C/C(=O)Cl.CC(C)(C)c1cc(N)cc(C(C)(C)C)c1O>>C/C=C/C(=O)Nc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1,,c1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20080194833A1,CCCCOC(=O)[C@@H](O)CC.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCCCOC(=O)[C@H](CC)OS(=O)(=O)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US04009170,CCOC1=NCCc2ccccc21.Cl.NN>>Cl.NNC1=NCCc2ccccc21,,CCO,,,,test
US20090163489A1,CC(=O)Nc1cn2nc(-c3cccc(N)c3)ccc2n1.O=S(=O)(Cl)c1cccc2cnccc12>>CC(=O)Nc1cn2nc(-c3cccc(NS(=O)(=O)c4cccc5cnccc45)c3)ccc2n1,,CN(C)C=O,,Cl,c1ccncc1,test
US20160039838A1,C#Cc1cccc(Nc2ncnc3cc(OCC)c([N+](=O)[O-])cc23)c1>>C#Cc1cccc(Nc2ncnc3cc(OCC)c(N)cc23)c1,[Fe],CCO,,Cl,[Na+].[OH-],test
US20020193367A1,Cc1cc(-c2cccc(C(=O)CC(=O)Nc3cc(Cl)c(N(C)CC(C)C)cc3NC(=O)OC(C)(C)C)c2)on1>>Cc1cc(-c2cccc(C3=Nc4cc(N(C)CC(C)C)c(Cl)cc4NC(=O)C3)c2)on1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140038957A1,CI.COC1(OC)CCN(C(=O)OC(C)(C)C)CC1O>>COC1CN(C(=O)OC(C)(C)C)CCC1(OC)OC,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20050250836A1,BrBr.COc1ccccc1-c1cc2c(ccn2C)c2c1C(=O)NC2=O>>COc1ccccc1-c1cc2c(c(Br)cn2C)c2c1C(=O)NC2=O,,CCOC(C)=O,ClC(Cl)Cl,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20080293694A1,CC(C)(C)OC(=O)N1CC(=O)c2cn(S(=O)(=O)c3ccccc3)c3cccc(c23)C1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=S(=O)(c1ccccc1)n1cc2c3c(cccc31)CNCC2O,,ClCCl,,CC(=O)O,[BH4-].[Na+],test
US20080247964A1,C1CC(N2CCC3(CCNCC3)CC2)C1.Clc1ccc(Cl)nn1>>Clc1ccc(N2CCC3(CC2)CCN(C2CCC2)CC3)nn1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060094767A1,Cc1ccc(S(=O)(=O)OCC2(C)CO2)cc1.O=c1[nH]nc(-c2ccc(OC(F)(F)F)cc2)o1>>CC1(Cn2nc(-c3ccc(OC(F)(F)F)cc3)oc2=O)CO1,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US04161592,CCCCCCCCS.Cc1cc(Nc2nc(Cl)nc(NC3CC(C)(C)NC(C)(C)C3)n2)cc(C(C)(C)C)c1O>>CCCCCCCCSc1nc(Nc2cc(C)c(O)c(C(C)(C)C)c2)nc(NC2CC(C)(C)NC(C)(C)C2)n1,,CO,,[Na],,test
US20100137594A1,CC(C)(C)OC(=O)Nc1cc(Cl)cc(CO)n1.O=S(Cl)Cl>>CC(C)(C)OC(=O)Nc1cc(Cl)cc(CCl)n1,,O,c1ccncc1,ClCCl,O=C([O-])O.[Na+],test
US20150018309A1,COC(=O)CS.Cc1nnc(Cl)c(C#N)c1C>>COC(=O)c1sc2nnc(C)c(C)c2c1N,,CC(C)(C)O,,O=C([O-])[O-].[K+].[K+],,test
US20060058337A1,CC1c2ccccc2-c2ccc(F)cc2N1C(=O)c1cccc(O)c1>>C[C@@H]1c2ccccc2-c2ccc(F)cc2N1C(=O)c1cccc(O)c1,,ClC(Cl)Cl,,,,test
US20100216808A1,NC(=O)c1nn(CCOC2CCCCO2)c2c1CCc1cnc(Nc3ccccc3OC(F)(F)F)nc1-2>>NC(=O)c1nn(CCO)c2c1CCc1cnc(Nc3ccccc3OC(F)(F)F)nc1-2,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20130302587A1,CC(=O)Cl.CO.N[C@H](Cc1ccccc1)C(=O)O>>COC(=O)[C@H](N)Cc1ccccc1.Cl,,CO,,,,test
US20140378431A1,CC(C)(C)OC(=O)N1CCC(n2cc(N)cn2)CC1.COc1ccc(-n2nnc3cnc(Cl)nc32)cc1>>COc1ccc(-n2nnc3cnc(Nc4cnn(C5CCNCC5)c4)nc32)cc1,,COCCO,,,,test
US04602030,O=C(Cn1ccnc1)CS(=O)(=O)c1ccccc1>>O=S(=O)(CC(O)Cn1ccnc1)c1ccccc1,,CO,,[Na],,test
US20110201580A1,CCOC(=O)CN1C[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)COC(C)=O)C1>>CCOC(=O)CN1C[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)C1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20070015743A1,CC(O)[C@H]1CCCN1.Oc1ccc(Nc2ncnc3cccc(F)c23)cc1Cl>>C[C@H](Oc1cccc2ncnc(Nc3ccc(O)c(Cl)c3)c12)[C@H]1CCCN1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20140051679A1,C[C@H](NC(=O)c1ccc2[nH]ncc2c1)C1CCCCC1.II>>C[C@H](NC(=O)c1ccc2[nH]nc(I)c2c1)C1CCCCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06248739B1,CN1C=C(C(=O)NCc2ccc(Cl)cc2)Cc2cc(CCl)ccc21.CN1CCCC1=O.OC1CNC1>>Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CC(O)C3)ccc21,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US05114461,C/C(=C/C(=O)O)C(F)(F)F.N>>CC(N)(CC(=O)O)C(F)(F)F,,[NH4+],[OH-],,,test
US20130267493A1,COC(=O)c1cn(C(=O)OC(C)(C)C)c2cc(Cl)c(-c3ccc(OCc4cccnc4)cc3)cc12>>O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(OCc4cccnc4)cc3)cc12,,CO,,[Na+].[OH-],,test
US20140221333A1,COc1ccc(CN)c(OC)c1.O=C(OCc1ccccc1)N1CCC[C@@H](c2nc(Br)c3c(Cl)ncc(Cl)n23)C1>>COc1ccc(CNc2ncc(Cl)n3c([C@@H]4CCCN(C(=O)OCc5ccccc5)C4)nc(Br)c23)c(OC)c1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20070185165A1,[N-]=[N+]=NCc1nonc1-c1noc(=O)n1-c1ccc(F)c(Cl)c1>>NCc1nonc1-c1noc(=O)n1-c1ccc(F)c(Cl)c1,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110245205A1,CC[Mg]Br.Clc1ccnc(Cl)n1>>CCc1ccnc(Cl)n1,,C1CCOC1,,[Cl-].[NH4+],,test
US20060223835A1,O=C[C@H]1C[C@@H](COCc2ccccc2)C1>>OC[C@H]1C[C@@H](COCc2ccccc2)C1,,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US20070093501A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(S)[C@@H](N)C(=O)O.COCCBr>>COCCSC(C)(C)[C@@H](NC(=O)OC(C)(C)C)C(=O)O,,CCO,,[Na+].[OH-],,test
US20070265346A1,COc1ccc(CCN(C)CCCC(C#N)(c2ccc(OC)c(OC)c2)C(C)C)cc1OC>>COc1ccc(CCN(C)CCCC(C#N)(c2ccc(OC)c(OC)c2)C(C)C)cc1OC,,CCO,,Cl,,test
US20120220622A1,CCOC(=O)CN(Cc1ccc(Br)cn1)C(N)=O>>O=C1CN(Cc2ccc(Br)cn2)C(=O)N1,,CO,,C[O-].[Na+],,test
US20030153570A1,CC(C)(C)OC(=O)NCC(=O)O.CC(C)N=C=NC(C)C.Cc1ccc(Cl)cc1-c1nc(Cl)nc(Nc2ccc(CO)cc2)n1>>Cc1ccc(Cl)cc1-c1nc(N)nc(Nc2ccc(COC(=O)CNC(=O)OC(C)(C)C)cc2)n1,,CN(C)C=O,,,,test
US04182881,Cc1cccc(C(N)=O)c1C.ClP(Cl)(Cl)(Cl)Cl.O=CO>>Cc1cccc(C(=O)NP(=O)(Cl)Cl)c1C,,ClC(Cl)(Cl)Cl,,,,test
US20130116216A1,COC(=O)C1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CC1>>O=C(O)C1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CC1,,C1CCOC1,O,[Li+].[OH-],,test
US20130059835A1,COc1c(C(C)n2ccc(=O)c3c(N)ncnc32)cc(Cl)c(C)c1C1CN(C(=O)OC(C)(C)C)C1.Cl>>COc1c(C(C)n2ccc(=O)c3c(N)ncnc32)cc(Cl)c(C)c1C1CNC1.Cl,,ClCCl,,C1COCCO1,,test
US04950796,Cc1c(COC2CCCCO2)cccc1C1CC1>>Cc1c(CO)cccc1C1CC1,,CO,,Cl,C[O-].[Na+],test
US20140303153A1,Cn1cc2c(c(N3CCOCC3)c1=O)C(=O)N(CCc1ccc3ccccc3n1)C2=O>>Cn1cc2c(c(N3CCOCC3)c1=O)CN(CCc1ccc3ccccc3n1)C2=O,[Zn],CC(=O)O,,,,test
US06093696,CC(=O)Cl.CO.N[C@@H](Cc1ccc(O)c([N+](=O)[O-])c1)C(=O)O>>COC(=O)[C@@H](N)Cc1ccc(O)c([N+](=O)[O-])c1.Cl,,CO,,,,test
US20100145060A1,C#CCCCCCC.II>>CCCCCC/C=C/I,,C1CCOC1,,,,test
US20130045942A1,CC(N)c1ccc(O)cc1.OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O>>CC(Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)c1ccc(O)cc1,,CCCO,,CCN(CC)CC,,test
US20070043080A1,ClCCCCCCBr.c1ccc2[nH]ccc2c1>>ClCCCCCCn1ccc2ccccc21,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20020143017A1,COc1ccc(S(=O)(=O)c2sc3ccc(Cl)cc3c2C)nn1>>Cc1c(S(=O)(=O)c2ccc(=O)[nH]n2)sc2ccc(Cl)cc12,,C1COCCO1,,Cl,,test
US20150336952A1,Cn1c(=O)n(C2CCOCC2)c2c3cc(-c4ccc(F)nc4)c(F)cc3ncc21.OCCCN1CCCCC1>>Cn1c(=O)n(C2CCOCC2)c2c3cc(-c4ccc(OCCCN5CCCCC5)nc4)c(F)cc3ncc21,,C1CCOC1,,[H-].[Na+],,test
US06989399B2,C1CCOC1.C[C@H](O)CCOC(c1ccccc1)(c1ccccc1)c1ccccc1.O=S(=O)(Nc1cc(Cl)ccc1Cl)c1ccc(Cl)cc1>>C[C@H](CCCOC(c1ccccc1)(c1ccccc1)c1ccccc1)N(c1cc(Cl)ccc1Cl)S(=O)(=O)c1ccc(Cl)cc1,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070244136A1,CC(=O)N(C)CCOc1cccc2ncnc(Cl)c12.Cc1ccc(Oc2ccc(N)cc2C)cn1>>CC(=O)N(C)CCOc1cccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c12,,CC(C)O,,,,test
US20060257987A1,CCOC(=O)C(C)(C)Oc1cccc(O)c1.CCc1ccc(OC(C)CCO)c(C(=O)c2ccccc2)c1>>CCOC(=O)C(C)(C)Oc1cccc(OCCC(C)Oc2ccc(CC)cc2C(=O)c2ccccc2)c1,,Cc1ccccc1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140336376A1,Nc1cccc(Br)c1O.O=C(Cl)CCl>>O=C1Cc2cccc(Br)c2ON1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20160002205A1,CNOC.O=C(O)c1ccnc(Cl)c1>>CON(C)C(=O)c1ccnc(Cl)c1,,ClCCl,,CCOCC,,test
US20100286125A1,CI.O=C(O)[C@@H](CC=CCOCc1ccccc1)C[C@@H](O)c1ccc(F)cc1>>CO[C@H](C[C@H](CC=CCOCc1ccccc1)C(=O)O)c1ccc(F)cc1,,C1CCOC1,,[H-].[Na+],,test
US20150152093A1,C[C@H](F)[C@H]1COC(=O)N1c1ccnc(F)n1.Cc1cc(-c2cnc([C@H](C)N)nc2)ccc1F>>Cc1cc(-c2cnc([C@H](C)Nc3nccc(N4C(=O)OC[C@@H]4[C@H](C)F)n3)nc2)ccc1F,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20100093714A1,N#Cc1cccc(-c2nc(N)c3ccsc3n2)c1.O=C1CCC(=O)N1Br>>N#Cc1cccc(-c2nc(N)c3cc(Br)sc3n2)c1,,O,,CN(C)C=O,,test
US20130274287A1,N.O=C(O)COC1CCc2c(-c3ccc(C(F)(F)F)cc3)cncc21>>NC(=O)COC1CCc2c(-c3ccc(C(F)(F)F)cc3)cncc21,,CN(C)C=O,ClCCl,Cl,O=C(n1ccnc1)n1ccnc1,test
US20150152065A1,Nc1ccccc1N.O=C(O)Cc1ccncc1>>c1ccc2[nH]c(Cc3ccncc3)nc2c1,,CCOC(C)=O,Cl,O=C([O-])[O-].[Na+].[Na+],,test
US20110224262A1,c1ccc(COCCn2ccc(-c3ccccc3)n2)cc1>>OCCc1cc(-c2ccccc2)n[nH]1,[Pd],C1CCOC1,,CC(=O)O,,test
US20070197626A1,CCOC(=O)Cc1ccc(OCC(=O)N2CC(C)(C)c3cc(-c4ccc(C(F)(F)F)cc4)ccc32)c(OCC)c1>>CCOc1cc(CC(=O)O)ccc1OCC(=O)N1CC(C)(C)c2cc(-c3ccc(C(F)(F)F)cc3)ccc21,,CCO,,Cl,[Na+].[OH-],test
US04990511,NCCN1CCCCC1.O=C(O)Cc1ccc(OCc2ccccc2)cc1OCc1ccccc1>>O=C(Cc1ccc(OCc2ccccc2)cc1OCc1ccccc1)NCCN1CCCCC1,,CN(C)C=O,O,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US05521147,Nc1c(F)cc(Cl)c2c1OCCC2.O=C(Cl)OC(Cl)(Cl)Cl>>O=C=Nc1c(F)cc(Cl)c2c1OCCC2,,Cc1ccccc1,,,,test
US20160083370A1,C1CNCCN1.Cc1nc(Br)sc1C(N)=O>>Cc1nc(N2CCNCC2)sc1C(N)=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US08093251B2,CC(=O)Cl.Cc1cc(O)n(-c2ccc(C(C)(C)C)cc2)n1>>CC(=O)Oc1cc(C)nn1-c1ccc(C(C)(C)C)cc1,,C1CCOC1,,CCN(CC)CC,O,test
US20020091150A1,CCc1nnc(N)o1.Cc1cc(C)n(C(=O)C2c3ccccc3Oc3ccccc32)n1>>CCc1nnc(NC(=O)C2c3ccccc3Oc3ccccc32)o1,,CN(C)C=O,,CC(C)=O,,test
US20090088458A1,COc1cnc(C2CC2)cc1CNC(=O)OC(C)(C)C.Cl.ClC(Cl)Cl>>COc1c[nH+]c(C2CC2)cc1C[NH3+].[Cl-].[Cl-],,ClC(Cl)Cl,,CCO,,test
US04179505,CCCn1c(C)nc2cc(C(=O)O)ccc21.O=S(Cl)Cl>>CCCn1c(C)nc2cc(C(=O)Cl)ccc21.Cl,,ClC(Cl)Cl,,,,test
US20090149468A1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2.Clc1nc(Cl)c2ccccc2n1>>CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2c1nc(Cl)nc2ccccc12,,CC(C)O,,,,test
US20020025935A1,CC(C)[C@H](NC(=O)c1cc2ccccc2n1C)C(=O)NC(CC(=O)OC(C)(C)C)C(O)COc1c(F)c(F)cc(F)c1F>>CC(C)[C@H](NC(=O)c1cc2ccccc2n1C)C(=O)NC(CC(=O)OC(C)(C)C)C(=O)COc1c(F)c(F)cc(F)c1F,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20070049616A1,O=S(Cl)Cl.OCCc1cncn1Cc1ccccc1-c1ccc(F)cc1>>Fc1ccc(-c2ccccc2Cn2cncc2CCCl)cc1,,ClCCl,,,,test
US20070149561A1,CCn1cc(-c2ccnc3[nH]ccc23)c(-c2ccc(N)cc2)n1.Nc1cccc(-c2ccccc2)c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCn1cc(-c2ccnc3[nH]ccc23)c(-c2ccc(NC(=O)Nc3cccc(-c4ccccc4)c3)cc2)n1,,C1CCOC1,O,CCN(CC)CC,,test
US04560692,CNC(=O)c1ccncc1>>CNC(=O)C1CCNCC1,O=[Pt],CCO,,,,test
US05606061,O=C1CCCCC1Cl.O=[N+]([O-])c1c[nH]cn1>>O=C1CCCCC1n1cnc([N+](=O)[O-])c1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20110319445A1,CCN(Cc1cc(C)cnc1Cl)C(=O)C1CC1.CCOC(=O)Cc1ccc(OC)c(B2OC(C)(C)C(C)(C)O2)c1>>CCOC(=O)Cc1ccc(OC)c(-c2ncc(C)cc2CN(CC)C(=O)C2CC2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20100222379A1,CI.COc1ccc(C(=Cc2ccc(OC)c(OC)c2)C(=O)O)cc1>>COC(=O)C(=Cc1ccc(OC)c(OC)c1)c1ccc(OC)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120101103A1,CCOC(=O)C1CCOc2cc(Oc3ccc(C(=O)Nc4cccc(Br)n4)cc3)c(Cl)cc21.OB(O)c1ccc(Cl)c(Cl)c1>>CCOC(=O)C1CCOc2cc(Oc3ccc(C(=O)Nc4cccc(-c5ccc(Cl)c(Cl)c5)n4)cc3)c(Cl)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],,test
US07157487B2,COC(=O)[C@@H]1C[C@H](O)CN1C(=O)OC(C)(C)C.Oc1ccccc1>>COC(=O)[C@@H]1C[C@H](Oc2ccccc2)CN1C(=O)OC(C)(C)C,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120252828A1,C1COCCN1.O=c1c2cc(Cc3ccc(Br)cc3)c3cnccc3c2ncn1[C@H]1CCCC[C@@H]1O>>O=c1c2cc(Cc3ccc(N4CCOCC4)cc3)c3cnccc3c2ncn1[C@H]1CCCC[C@@H]1O,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,CCOC(C)=O,Cc1ccccc1,CC(C)(C)[O-].[K+],,test
US20080004330A1,CC(C)(C)OC(=O)N1CC(CN)C1.O=Cc1ccc(Cl)cc1Cl>>CC(C)(C)OC(=O)N1CC(CNCc2ccc(Cl)cc2Cl)C1,,ClCCCl,,CC(=O)O,[Na+].[OH-],test
US20150005304A1,Cc1cc(C(=O)N2CCC3(CC2)CC(O)CC(c2cccnc2)O3)ccc1OC(C)C>>Cc1cc(C(=O)N2CCC3(CC2)CC(=O)CC(c2cccnc2)O3)ccc1OC(C)C,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20130060047A1,Cc1cccc2[nH]cc(C(=O)CC3CCCCCC3)c12.O=C1OCCO1>>Cc1cccc2c1c(C(=O)CC1CCCCCC1)cn2CCO,,O,,C1CCC2=NCCCN2CC1,,test
US20110046157A1,CCOC(=O)c1sc2c(c1C)CNCC2.Cn1cccc1C(=O)O>>CCOC(=O)c1sc2c(c1C)CN(C(=O)c1cccn1C)CC2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080021026A1,CC(=O)c1sc2ccc(Cl)cc2c1Br.OB(O)c1ccccc1>>CC(=O)c1sc2ccc(Cl)cc2c1-c1ccccc1,,Cc1ccccc1,,CCO,O=C([O-])[O-].[K+].[K+],test
US20060154926A1,CC(C)[C@H](CO)Cc1ccc(C(C)(C)C)cc1.O=C1CCC(=O)N1Br>>CC(C)[C@H](CBr)Cc1ccc(C(C)(C)C)cc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04036977,BrCCCCBr.Nc1ccc(OC23CC4CC(CC(C4)C2)C3)c(Cl)c1>>Clc1cc(N2CCCC2)ccc1OC12CC3CC(CC(C3)C1)C2,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20120046278A1,CI.Cc1ccc(NC(=O)N2CCN(c3nc(N)nc4sc(-c5cccnc5)nc34)CC2)cc1>>Cc1ccc(N(C)C(=O)N2CCN(c3nc(N)nc4sc(-c5cccnc5)nc34)CC2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US09255096B1,CCOC(=O)C1CN(Cc2ccccc2)CCC1=O>>CCOC(=O)C1CNCCC1=O,[Pd],CCO,,,,test
US20100029650A1,CCC(Oc1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1)C1CCN(C(=O)OC(C)C)CC1>>CC[C@H](Oc1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1)C1CCN(C(=O)OC(C)C)CC1,,CO,,O=C=O,,test
US20100286123A1,C=Cc1ccc2c(c1OC)COC2=O.O=C(OO)c1cccc(Cl)c1>>COc1c(C2CO2)ccc2c1COC2=O,,ClCCl,,,,test
US20060004046A1,CCOc1c(C#N)cnc2ccc(/C=C3\SC(SC)=NC3=O)cc12.NCCc1cccc(F)c1>>CCOc1c(C#N)cnc2ccc(/C=C3\SC(NCCc4cccc(F)c4)=NC3=O)cc12,,CC#N,,CCN(C(C)C)C(C)C,,test
US20070049618A1,CC(C)Oc1cc(OCCN(C)C)ccc1[N+](=O)[O-]>>CC(C)Oc1cc(OCCN(C)C)ccc1N,[Pd],CCOC(C)=O,,[H][H],,test
US20160221972A1,COC(=O)c1ccc(CNC[C@@H](C)O)c(Br)c1>>COC(=O)c1ccc2c(c1)O[C@H](C)CNC2,[Cu]I,CC(C)O,,O=C([O-])[O-].[K+].[K+],,test
US06133266,CN(C)C(=O)COc1ccc2c(c1)C[C@@H](NC[C@H](O)c1ccc3c(c1)COC(C)(C)O3)CC2>>CN(C)C(=O)COc1ccc2c(c1)C[C@@H](NC[C@H](O)c1ccc(O)c(CO)c1)CC2,,COCCOC,,Cl,O=C([O-])O.[Na+],test
US04719219,CCCCCCCCCC(=O)Cl.CCCN1CCCC(c2cccc(O)c2)C1.Cl>>CCCCCCCCCC(=O)Oc1cccc(C2CCCCN2CCC)c1.Cl,,CCOCC,ClCCl,Cl,c1ccncc1,test
US20120101099A1,O=C(C=Cc1cccc(CNS(=O)(=O)Cn2cc(-c3ccccc3)nn2)c1)NOC1CCCCO1>>O=C(C=Cc1cccc(CNS(=O)(=O)Cn2cc(-c3ccccc3)nn2)c1)NO,,CO,,C1COCCO1,Cl,test
US20040058964A1,BrBr.CSc1nccc(C)n1>>CSc1nccc(CBr)n1,,CC(=O)O,,,,test
US20080188528A1,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2.O=C(O)c1cccn(Cc2ccccc2Cc2ccccc2)c1=O>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)c2cccn(Cc3ccccc3Cc3ccccc3)c2=O)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US03966947,N#CSc1ccc(N=C=O)cc1.OCc1cccnc1>>N#CSc1ccc(NC(=O)OCc2cccnc2)cc1,,c1ccccc1,,,,test
US20080113966A1,C=C(C)CBr.CCOC(=O)CC1CCN(C(=O)OCc2ccccc2)CC1>>C=C(C)CC(C(=O)OCC)C1CCN(C(=O)OCc2ccccc2)CC1,,C1CCOC1,,,,test
US20080318935A1,CC(C)(C)OC(=O)N1CCCn2c(Br)nc(C(=O)O)c2C1.CNC(=O)[C@@H](N)CC(C)C>>CNC(=O)[C@H](CC(C)C)NC(=O)c1nc(Br)n2c1CN(C(=O)OC(C)(C)C)CCC2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20100292196A1,CCn1ncc2c(NC3CCC(O)CC3)c(C3=NOC4(CCCCC4)C3)cnc21>>CCn1ncc2c(NC3CCC(=O)CC3)c(C3=NOC4(CCCCC4)C3)cnc21,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20020165241A1,COc1nccnc1NCC1CCNCC1.Cc1ccc(COC(=O)ON2C(=O)CCC2=O)cc1>>COc1nccnc1NCC1CCN(C(=O)OCc2ccc(C)cc2)CC1,,CCOC(C)=O,CN(C)C=O,,,test
US20160207905A1,Cc1cc(Nc2ncc(Cl)c(NC3CCCC(NC(=O)OC(C)(C)C)C3)n2)sn1>>Cc1cc(Nc2ncc(Cl)c(NC3CCCC(N)C3)n2)sn1,,CO,ClCCl,C1COCCO1,Cl,test
US20100010219A1,CCOC(=O)c1csc(N2CCC(n3ncc(C(=O)N4CCC(c5ccccc5C(F)(F)F)C4)c3C3CC3)CC2)n1>>O=C(O)c1csc(N2CCC(n3ncc(C(=O)N4CCC(c5ccccc5C(F)(F)F)C4)c3C3CC3)CC2)n1,,C1CCOC1,CO,[Na+].[OH-],,test
US20010006969A1,C=CCNc1nc(Cl)nc2ccc([N+](=O)[O-])cc12.NC1CCCCC1>>C=CCNc1nc(NC2CCCCC2)nc2ccc([N+](=O)[O-])cc12,,O,,,,test
US05276168,CC1(C)Oc2ccc(C#N)cc2[C@@H](N)[C@@H]1O.S=C=Nc1ccccc1>>CC1(C)Oc2ccc(C#N)cc2[C@@H](NC(=S)Nc2ccccc2)[C@@H]1O,,CCO,,,,test
US05208247,CCCCCCCCCCCCCCOc1ccc(CBr)cc1.CS(=O)(=O)NCc1ccccn1>>CCCCCCCCCCCCCCOc1ccc(CN(Cc2ccccn2)S(C)(=O)=O)cc1,,C1CCOC1,,[H-].[Na+],,test
US20100190825A1,CCO[C@@H]1CC[C@@H](N2CCC(N)CC2)CC1.N#Cc1cc(I)c(N)cc1Cl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCO[C@@H]1CC[C@@H](N2CCC(NC(=O)Nc3cc(Cl)c(C#N)cc3I)CC2)CC1,,C1COCCO1,ClCCl,,,test
US20140163173A1,Cc1cc(C=O)c(O)c([Si](C(C)C)(C(C)C)C(C)C)c1>>Cc1cc(CO)c(O)c([Si](C(C)C)(C(C)C)C(C)C)c1,,CCOCC,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20120208859A1,C=CCOc1cc(F)c(F)c(F)c1[N+](=O)[O-].Nc1ccc(I)cc1>>C=CCOc1cc(F)c(F)c(Nc2ccc(I)cc2)c1[N+](=O)[O-],,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20130310358A1,CCOC(=O)c1ccc(O)cc1.O=[N+]([O-])c1cnc(Cl)nc1Cl>>CCOC(=O)c1ccc(Oc2nc(Cl)ncc2[N+](=O)[O-])cc1,,CC(C)=O,,O=C([O-])O.[Na+],,test
US20050080124A1,COc1ccc(N)cc1-c1c(Br)cnn1C.S=C=Nc1ccc(Cl)cc1>>COc1ccc(NC(=S)Nc2ccc(Cl)cc2)cc1-c1c(Br)cnn1C,,ClCCl,,,,test
US20090318448A1,Cn1nc(Cl)cc(Cl)c1=O.Nc1ccc(C(=O)N2CCOCC2)cn1>>Cn1nc(Cl)cc(Nc2ccc(C(=O)N3CCOCC3)cn2)c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20030018046A1,O=C(Cc1cccnc1CO)NCc1ccccc1>>OCc1ncccc1CCNCc1ccccc1,,C1CCOC1,,B,,test
US03971772,CC(N)C1(c2ccccc2)OCCO1.CCOC(=O)Cl>>CCOC(=O)NC(C)C1(c2ccccc2)OCCO1,,ClCCl,,CCN(CC)CC,,test
US20070244092A1,C1CNOC1.CC(C)(C)c1nc2cc(S(=O)(=O)Cl)ccc2n1CC1CCOCC1>>CC(C)(C)c1nc2cc(S(=O)(=O)N3CCCO3)ccc2n1CC1CCOCC1,CN(C)c1ccncc1,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20100056576A1,CC(CO)C1OC(=O)N[C@@H]1COCc1ccccc1>>CC(CO)C1OC(=O)N[C@@H]1CO,[Pd],CO,,,,test
US20140128372A1,CCOC(=O)C(Cl)C(C)=O.Nc1ncc(F)cc1O>>CCOC(=O)c1c(C)nc2c(O)cc(F)cn12,,CCO,,,,test
US20090214675A1,C/C(N)=C/C(=O)OC(C)C.CC([O-])=CC#N.Cc1cc(=O)c2cccc(C=O)c2o1>>CC1=C(C#N)C(c2cccc3c(=O)cc(C)oc23)C(C(=O)OC(C)C)=C(C)N1,,CC(C)O,,CC(=O)O,,test
US20140088101A1,COC(=O)c1cc(Br)c(=O)n(-c2ccccc2)c1C.O=C1CCC(=O)N1Br>>COC(=O)c1cc(Br)c(=O)n(-c2ccccc2)c1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20030045558A1,CCOC(=O)C(C)(C)Br.Oc1ccc(OCc2ccccc2)cc1Br>>CCOC(=O)C(C)(C)Oc1ccc(OCc2ccccc2)cc1Br,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040087798A1,Cc1ncn(-c2cccc(N)c2)c1C.O=C(O)C=Cc1ccc(F)cc1Cl>>Cc1ncn(-c2cccc(NC(=O)/C=C/c3ccc(F)cc3Cl)c2)c1C,,CO,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US04880784,NC1=C2SC(=O)NC2N([C@@H]2O[C@H](COC(=O)c3ccccc3)[C@@H](OC(=O)c3ccccc3)[C@H]2OC(=O)c2ccccc2)C=N1.Nc1ncnc2c1sc(=O)n2[C@@H]1O[C@H](COC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1>>NC1=C2SC(=O)NC2N([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C=N1.Nc1ncnc2c1sc(=O)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O,,CO,,C[O-].[Na+],,test
US03987160,CCOC(=O)C(C#N)=NO.COc1c(Cl)cc(Cl)cc1C(=N)N>>COc1c(Cl)cc(Cl)cc1-c1nc(N)c(N=O)c(=O)[nH]1,,CC(=O)O,CO,O,[Na],test
US20080207654A1,CCCc1nc(CC)n(-c2ccc(N3CCC4(CC3)OCCO4)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCc1nc(CC)n(-c2ccc(N3CCC4(CC3)OCCO4)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,O,,CS(C)=O,[Cl-].[Na+],test
US20140364432A1,Cc1cccc(CCOS(C)(=O)=O)n1.Oc1ccccc1>>Cc1cccc(CCOc2ccccc2)n1,,CC(C)O,,[Na+].[OH-],,test
US20140350007A1,CCOc1cc(C(=O)OC)cc([N+](=O)[O-])c1>>CCOc1cc(N)cc(C(=O)OC)c1,[Pd],CC(C)=O,,CO,O,test
US05151420,Nc1ccc(C2=NNC(=O)CC2)cc1.O=C(CCc1ccccc1)c1ccc(O)cc1O>>O=C1CCC(c2ccc(N=C(CCc3ccccc3)c3ccc(O)cc3O)cc2)=NN1,,CCOC(C)=O,,,,test
US05840740,BrCc1ccccc1.C[C@H](CCCO[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@H]4C[C@@H](OC5CCCCO5)CC[C@]4(C)[C@H]3CC[C@]12C>>C[C@H](CCCO[Si](C)(C)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3[C@H](OCc4ccccc4)C[C@H]4C[C@@H](OC5CCCCO5)CC[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,CN(C)C=O,,test
US03933824,CC(=O)CCCC(=O)N1CCN(c2ccccc2)CC1.NNc1ccccc1>>Cc1[nH]c2ccccc2c1CCC(=O)N1CCN(c2ccccc2)CC1,,CC(=O)O,,,,test
US06514911B1,N#Cc1cccc(C(F)(F)F)c1.O=C(N=C(C(F)(F)F)C(F)(F)F)C(F)(F)C(F)(F)F>>FC(F)(F)c1cccc(C2=NC(C(F)(F)F)(C(F)(F)F)N=C(C(F)(F)C(F)(F)F)O2)c1,,CCOCC,,,,test
US04822914,NC(Cc1ccccc1[N+](=O)[O-])c1ccccc1.O=C(Cl)C1CCCCC1>>O=C(NC(Cc1ccccc1[N+](=O)[O-])c1ccccc1)C1CCCCC1,,Cc1ccccc1,c1ccncc1,,,test
US05656573,CC(=O)C(C(=O)c1ccccc1)C(=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]>>O=C(CC(=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-])c1ccccc1,,CCO,,O,O=S(=O)(O)O,test
US20030166637A1,CC(C)(C)OC(=O)N1CCN(CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)CC1>>O=C(NCC(F)(F)F)C1(CCCCN2CCNCC2)c2ccccc2-c2ccccc21,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20070270414A1,COC(=O)c1cc(S(C)(=O)=O)c(F)cc1C.O=S1(=O)CC(c2ccc(F)cc2)CN1>>COC(=O)c1cc(S(C)(=O)=O)c(N2CC(c3ccc(F)cc3)CS2(=O)=O)cc1C,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US04107304,O=C(Cl)Cl.O=C1NCCN1c1ccccc1>>O=C(Cl)N1CCN(c2ccccc2)C1=O,,C1CCOC1,,,,test
US20070173532A1,Cc1cccc([N+](=O)[O-])c1N.N#CCC(=O)O>>Cc1cccc([N+](=O)[O-])c1NC(=O)CC#N,,c1ccccc1,,ClP(Cl)(Cl)(Cl)Cl,,test
US04272437,CCOC(=O)N1C(=O)c2ccccc2C1=O.NC[C@@H]1C(=O)N[C@H]1SC(c1ccccc1)(c1ccccc1)c1ccccc1>>O=C1N[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)[C@@H]1CN1C(=O)c2ccccc2C1=O,,c1ccccc1,,,,test
US20070032487A1,CN.Cc1nc(NC(=O)n2ccnc2)sc1-c1ccncc1>>CNC(=O)Nc1nc(C)c(-c2ccncc2)s1,,CN(C)C=O,O,,,test
US20160145238A1,CCOC(=O)c1n[nH]c(C2CC2)c1C.COc1ccc(CBr)cc1>>CCOC(=O)c1nn(Cc2ccc(OC)cc2)c(C2CC2)c1C,,C1CCOC1,,O,[H-].[Na+],test
US20080090861A1,CCc1cc(O)n(-c2cccc(C)n2)n1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCc1cc(OS(=O)(=O)C(F)(F)F)n(-c2cccc(C)n2)n1,,ClCCl,,CCN(CC)CC,,test
US20090306129A1,CCOC(=O)c1cnc2c(cnn2CC)c1NC1CC1>>CCn1ncc2c(NC3CC3)c(C(=O)O)cnc21,,CCO,,O,[Na+].[OH-],test
US04788206,CCC/C(=C\C=C\C(=O)OC)c1ccc(OC)cc1>>CCC/C(=C\C=C\C(=O)O)c1ccc(OC)cc1,,CO,,[Na+].[OH-],,test
US20090099227A1,CC(C)(C)OC(=O)N1CCC(Cc2noc(-c3cc4cnccc4o3)n2)CC1>>c1cc2oc(-c3nc(CC4CCNCC4)no3)cc2cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090099207A1,BrP(Br)Br.COCc1cc(C)cc(CO)c1>>COCc1cc(C)cc(CBr)c1,,C1CCOC1,,O,,test
US20070275987A1,COC(=O)COCCc1cccc(F)c1.NC(=O)c1cccnc1N>>O=c1[nH]c(COCCc2cccc(F)c2)nc2ncccc12,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04935430,CC(=O)C(Br)c1ccc(C#N)cc1.CC(N)=S>>Cc1nc(C)c(-c2ccc(C#N)cc2)s1,,Cc1ccccc1,,c1ccncc1,,test
US20040204397A1,CCOC(=O)c1cc2cc(Br)cc(C)c2[nH]1>>Cc1cc(Br)cc2cc[nH]c12,,CCO,O,[K+].[OH-],,test
US05147445,CCN(CC)C(=O)Cl.COc1c(C)c(C)cc(C)c1Sc1nc[nH]n1>>CCN(CC)C(=O)n1cnc(Sc2c(C)cc(C)c(C)c2OC)n1,,c1ccncc1,,,,test
US06562827B1,C1CNCCN1.CCOC(=O)c1cccnc1Cl>>CCOC(=O)c1cccnc1N1CCNCC1,,CCO,,,,test
US20100197908A1,CC(=O)N(C)C1CCN(C(=O)OC(C)(C)C)CC1.O=C(O)C(F)(F)F>>CC(=O)N(C)C1CCNCC1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20150284395A1,CCOC(=O)CC(=O)c1ccc(Cl)c(OC)c1.N#CCc1cn[nH]c1N>>COc1cc(-c2cc(=O)n3ncc(CC#N)c3[nH]2)ccc1Cl,Cc1ccc(S(=O)(=O)O)cc1,CCCCO,,,,test
US06140351,O=C(Nc1ccc(Cl)cc1)c1cc(Cl)ccc1NC(=O)c1scc(CCl)c1Cl.c1c[nH]cn1>>O=C(Nc1ccc(Cl)cc1)c1cc(Cl)ccc1NC(=O)c1scc(Cn2ccnc2)c1Cl,,CN(C)C=O,,[Na],,test
US20060128695A1,CO.COc1cc2c(cc1OC)N(C)C(=O)CN=C2c1cccc(N)c1.COc1cc2c(cc1OC)N(C)C(=O)CN=C2c1cccc([N+](=O)[O-])c1>>CCCC1N=C(c2cccc(CO)c2)c2cc(OC)c(OC)cc2N(C)C1=O,[Pd],,,,,test
US20050222294A1,Cc1ccc(P(=O)(O)C(=O)c2ccccc2)c(C)c1C.O=S(Cl)Cl>>Cc1ccc(P(=O)(Cl)C(=O)c2ccccc2)c(C)c1C,,Cc1ccccc1,,c1ccncc1,,test
US06458781B1,CC(C)C[C@@H](C=O)NC(=O)OC(C)(C)C.Fc1ccc(C(c2ccc(F)cc2)N2CCNCC2)cc1>>CC(C)C[C@@H](CN1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)NC(=O)OC(C)(C)C,,CC(=O)O,CO,Cl,[BH3-]C#N.[Na+],test
US06288061B1,O=C(Nc1nccs1)c1nc(-c2ccc([N+](=O)[O-])cc2)[nH]c1-c1ccc([N+](=O)[O-])cc1>>Nc1ccc(-c2nc(C(=O)Nc3nccs3)c(-c3ccc(N)cc3)[nH]2)cc1,,CO,Cl,Cl[Sn]Cl,,test
US04637988,Cc1cccc(C)c1O.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>Cc1cc(C(=O)c2ccc([N+](=O)[O-])cc2)cc(C)c1O,,O=[N+]([O-])c1ccccc1,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20040097590A1,CC(=O)OC(C)=O.COC(=O)CC(NC(=O)CCc1ccccc1)C(=O)O>>COC(=O)CC(NC(=O)CCc1ccccc1)C(C)=O,,c1ccncc1,,,,test
US20050272669A1,CC(=O)OC[C@H]1O[C@@H](Oc2n[nH]c(C(C)C)c2Cc2ccc(OCCCO)cc2C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O.CS(=O)(=O)Cl>>CC(=O)OC[C@H]1O[C@@H](Oc2n[nH]c(C(C)C)c2Cc2ccc(OCCCOS(C)(=O)=O)cc2C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O,,ClCCl,,CCN(CC)CC,Cl,test
US04125726,COC(=O)c1nc(SC)n2c1CN=C(c1ccccc1Cl)c1cc(Cl)ccc1-2.N>>CSc1nc(C(N)=O)c2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2,,CO,,[Br-].[K+],,test
US20100261755A1,CCOC(=O)CC(=O)[C@H]1CCN(C(=O)OC)[C@@H](Cc2cc(F)cc(F)c2)C1.NO>>COC(=O)N1CC[C@H](c2cc(=O)[nH]o2)C[C@@H]1Cc1cc(F)cc(F)c1,,CO,O,Cl,[Na+].[OH-],test
US20140201855A1,O=C1CCc2cc([N+](=O)[O-])ccc2N1>>O=[N+]([O-])c1ccc2c(c1)CCCN2,,C1CCOC1,,B,,test
US20120015908A1,O=C1CC(c2ccccc2F)=Nc2ccc3c(c21)OCO3>>O=C1CC(c2ccccc2F)=Nc2ccc(O)c(O)c21,[Pd],CO,,,,test
US20100105659A1,CN(C)CCN.O=C=NS(=O)(=O)Cl.OCCCl>>CN(C)CCNS(=O)(=O)N1CCOC1=O,,ClCCl,,CCN(CC)CC,,test
US04889858,O=C1c2ccccc2COc2cc(F)ccc21>>OC1c2ccccc2COc2cc(F)ccc21,,CO,,O,[BH4-].[Na+],test
US20150182507A1,C1COCCN1.O=C(Cl)COCc1nc2ccccn2c1C#Cc1ccc(F)cc1>>O=C(COCc1nc2ccccn2c1C#Cc1ccc(F)cc1)N1CCOCC1,,ClCCl,,O,,test
US20010004669A1,Br[Mg]c1ccccc1.CN1CCN(c2cccc3ccc(C(=O)c4ccccc4)cc23)CC1>>CN1CCN(c2cccc3ccc(C(O)(c4ccccc4)c4ccccc4)cc23)CC1,,C1CCOC1,,[Cl-].[NH4+],,test
US20040067933A1,CC(C)(C)OC(=O)CNC(=O)[C@H](NC(=O)OCc1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)CNC(=O)[C@H](N)c1ccccc1,[Pd],CCO,Cc1ccccc1,,,test
US20060189606A1,CCn1c(-c2ccc(NC(=O)NCCCl)cc2)c(C#N)c2ccc(OC)cc21>>CCn1c(-c2ccc(N3CCNC3=O)cc2)c(C#N)c2ccc(OC)cc21,,CO,,[K+].[OH-],,test
US05612377,CC(C)CN(OCc1ccccc1)C(=O)OC(C)(C)C>>CC(C)CN(O)C(=O)OC(C)(C)C,[Pd],CCO,,O=C[O-].[NH4+],,test
US20120238545A1,O=C(c1nn(C2CCCN(CCCl)C2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1.O=C1CCCN1>>O=C1CCCN1CCN1CCCC(n2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)C1,,CC#N,ClCCl,[H-].[Na+],,test
US20050038035A1,C=C(C)c1ccc(-c2ccc(C(F)(F)F)cc2)c(C(=O)O)c1>>CC(C)c1ccc(-c2ccc(C(F)(F)F)cc2)c(C(=O)O)c1,[Pd],CO,,,,test
US20090156642A1,CCOC(=O)c1cc(O)n(-c2ccccc2F)n1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1cc(OS(=O)(=O)C(F)(F)F)n(-c2ccccc2F)n1,,C1CCOC1,,CCN(CC)CC,O,test
US20100286123A1,COC(=O)Cc1cc(OC)c(C#N)cc1Cl>>COc1cc(CCO)c(Cl)cc1C#N,,C1CCOC1,CCOCC,[BH4-].[Li+],,test
US20050209241A1,CC(C)(C)OC(=O)N1CCN(c2ccc(C(F)(F)F)cc2C(F)(F)F)CC1.Cl>>Cl.FC(F)(F)c1ccc(N2CCNCC2)c(C(F)(F)F)c1,,C1COCCO1,,,,test
US20020128262A1,CCOC(=O)CN1CCN=C(C=Cc2ccc(Cl)c(Cl)c2)c2ccccc21>>O=C(O)CN1CCN=C(C=Cc2ccc(Cl)c(Cl)c2)c2ccccc21,,CCO,,[Na+].[OH-],,test
US20090281140A1,COc1ccc(C(C)=O)c(NC(=O)c2cccc(C(C)C)n2)c1C>>COc1ccc2c(O)cc(-c3cccc(C(C)C)n3)nc2c1C,,c1ccncc1,,O,[K+].[OH-],test
US20160214972A1,CC(C)(C)OC(=O)COCCCC=O.CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=S)N1c1ccc(-c2ccc(N)cc2)cc1>>CC(C)(C)OC(=O)COCCCCNc1ccc(-c2ccc(N3C(=S)N(c4ccc(C#N)c(C(F)(F)F)c4)C(=O)C3(C)C)cc2)cc1,,ClCCl,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20120165343A1,COc1cc(C#N)ccc1Br.OB(O)c1ccc(C(F)(F)F)cc1>>COc1cc(C#N)ccc1-c1ccc(C(F)(F)F)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,[F-].[K+],,test
US07176310B1,Cc1ccc(O)c(C)c1.O=C(O)COc1ncc(C(=O)Nc2ccc(F)cc2)cn1>>Cc1ccc(OC(=O)COc2ncc(C(=O)Nc3ccc(F)cc3)cn2)c(C)c1,,CO,ClCCl,,,test
US20130196952A1,CC(O)CBr.CC1(C)OB(c2cn[nH]c2)OC1(C)C>>CC(O)Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160221945A1,CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)O.NCc1cc(-c2cnc(C(F)(F)F)nc2)ncn1>>CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)NCc1cc(-c2cnc(C(F)(F)F)nc2)ncn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090137580A1,Cn1ccc2ncnc(Oc3ccc(N)c(Cl)c3)c21.Nc1ccnc(Cl)c1.O=C(Cl)Oc1ccccc1>>Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4ccnc(Cl)c4)c(Cl)c3)c21,,CN1CCCC1=O,,c1ccncc1,,test
US20030050330A1,CSc1ccc(CO)cc1.O=S([O-])OO>>CS(=O)(=O)c1ccc(CO)cc1,,O,,CO,,test
US20100120785A1,CCOC(=O)C(=CN(C)C)C(C)=O.NNc1ccccn1>>CCOC(=O)c1cnn(-c2ccccn2)c1C,,CCO,,,,test
US20160168167A1,CC(COCc1ccccc1)OS(C)(=O)=O.O=Cc1cccc(O)c1Br>>CC(COCc1ccccc1)Oc1cccc(C=O)c1Br,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130137699A1,BrCc1ccccc1.O=C1C2CC3CC1CC(c1cc(Br)ccc1O)(C3)C2>>O=C1C2CC3CC1CC(c1cc(Br)ccc1OCc1ccccc1)(C3)C2,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20020107278A1,BrCCOc1ccccc1.CC(C)(C)OC(=O)N1CCc2[nH]c3c(Cl)c(Cl)ccc3c2CC1>>CC(C)(C)OC(=O)N1CCc2c(n(CCOc3ccccc3)c3c(Cl)c(Cl)ccc23)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20040019098A1,O=C1Cc2ccccc2N1.O=C1OCc2ccccc21>>O=C1Nc2ccccc2C1=C1OCc2ccccc21,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20050282858A1,O=C(N1CCC(O)C1)C1(c2ccc(Cl)cc2Cl)CC1>>O=C1CCN(C(=O)C2(c3ccc(Cl)cc3Cl)CC2)C1,,O,,CC(C)=O,,test
US20080153812A1,CNC(=O)c1cccc(C=O)c1.COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CNC(=O)c1cccc(/C=C/C(=O)OC)c1,,ClCCl,,,,test
US20140148433A1,COC=C(C(=O)OC)C(=O)OC.N=C(N)c1nn(Cc2ccccc2F)c2ncccc12>>COC(=O)c1cnc(-c2nn(Cc3ccccc3F)c3ncccc23)nc1O,,CO,,Cl,C[O-].[Na+],test
US20140288123A1,C[Mg]Br.O=Cc1ccc(Br)cc1F>>CC(O)c1ccc(Br)cc1F,,C1CCOC1,,,,test
US20140329771A1,CCOC(=O)C(C)C(=O)OCC.IC(I)I>>CCOC(=O)C(C)(C(=O)OCC)C(I)I,,CCOCC,,Cl,[H-].[Na+],test
US05039672,O=C1N(OCc2ccccc2)CCC12CCOc1ccc(F)cc12>>O=C1N(O)CCC12CCOc1ccc(F)cc12,[Pd],CO,,,,test
US20030069428A1,CC(=O)OC1CC(N2C(=O)c3cccc(C)c3C2=O)C(=O)NC1=O>>Cc1cccc2c1C(=O)N(C1CC(O)C(=O)NC1=O)C2=O,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080207621A1,Nc1cccc(S(N)(=O)=O)c1.O=C=NC12CC3CC(CC(C3)C1)C2>>NS(=O)(=O)c1cccc(NC(=O)NC23CC4CC(CC(C4)C2)C3)c1,,CCO,,,,test
US03984467,CCCCC(=N)N.O=C=NC1CCCCC1>>CCCCC(=N)NC(=O)NC1CCCCC1,,CC(C)=O,,Cl,[Na],test
US20130261077A1,CNC(=O)c1cccc(-c2ccc(-c3ccc([C@H]4O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H]4OC(C)=O)cc3)c(C)c2)c1>>CNC(=O)c1cccc(-c2ccc(-c3ccc([C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)cc3)c(C)c2)c1,,CO,,CO[Na],,test
US06191127B1,CCC1Oc2ccccc2NC1=O.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CCC1Oc2ccccc2NC1=S,,c1ccncc1,,,,test
US20030220350A1,CC(Nc1ccc(C(C)(C)C)cc1)c1ccc(C(=O)Nc2nn[nH]n2)cc1.O=C=Nc1ccc(OC(F)(F)F)cc1>>CC(c1ccc(C(=O)Nc2nn[nH]n2)cc1)N(C(=O)Nc1ccc(OC(F)(F)F)cc1)c1ccc(C(C)(C)C)cc1,,CN(C)C=O,,,,test
US20050059723A1,Cc1c(C=O)c2cc(Br)ccc2n1-c1ccc(O)cc1.NO>>Cc1c(C=NO)c2cc(Br)ccc2n1-c1ccc(O)cc1,,c1ccncc1,,CO,Cl,test
US20100081644A1,CCOC(=O)C(C)(C)SC[C@@H]1CCCCO1>>CC(C)(SC[C@@H]1CCCCO1)C(=O)O,,C1COCCO1,O,[Li+].[OH-],,test
US20090156594A1,Cn1cc(-c2cnc3ccc(CC(=O)NNC(=S)[S-])cc3c2)cn1.NN>>Cn1cc(-c2cnc3ccc(Cc4nnc(S)n4N)cc3c2)cn1,,O,,Cl,,test
US04572912,CC(=O)O.Cc1c(C)c2c(c(C)c1O)CCC(C)(COc1ccc(CC3SC(=N)NC3=O)cc1)O2>>Cc1c(C)c2c(c(C)c1O)CCC(C)(COc1ccc(CC3SC(=O)NC3=O)cc1)O2,,O,,Cl,,test
US03989707,CC1CC(n2c(=O)[nH]c3cc(Cl)ccc32)CCN1.Fc1ccc(C(CCCCl)c2ccc(F)cc2)cc1>>CC1CC(n2c(=O)[nH]c3cc(Cl)ccc32)CCN1CCCC(c1ccc(F)cc1)c1ccc(F)cc1,,CC(=O)CC(C)C,O,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US20110190489A1,Cc1ccc(S(=O)(=O)n2ccc3c2ncc2c(-c4ccc(C(C)(C)O)cc4)ncn23)cc1.O=C1CCC(=O)N1Br>>Cc1ccc(S(=O)(=O)n2ccc3c2ncc2c(-c4ccc(C(C)(C)O)cc4)nc(Br)n23)cc1,,CN(C)C=O,O,,,test
US20140018313A1,COC(=O)N[C@H](C(=O)O)[C@@H](C)OC.COC[C@@H]1CN[C@H](c2ncc(-c3cc4c5c(c3)OCc3cc(-c6cnc([C@@H]7C[C@H](C)CN7C(=O)[C@H](NC(=O)OC)c7ccccc7)[nH]6)cc(c3-5)OC4)[nH]2)C1>>COC[C@H]1C[C@@H](c2ncc(-c3cc4c5c(c3)OCc3cc(-c6cnc([C@@H]7C[C@H](C)CN7C(=O)[C@H](NC(=O)OC)c7ccccc7)[nH]6)cc(c3-5)OC4)[nH]2)N(C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC)C1,,CCN(C(C)C)C(C)C,CN(C)C=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20110275797A1,CC(=O)OC(C)=O.CCCOc1ccc(O)c(C(=O)O)c1>>CCCOc1ccc(OC(C)=O)c(C(=O)O)c1,,ClCCl,c1ccncc1,,,test
US04426380,C=CC(C)c1cc(C)ccc1O.CC(=O)Cl>>C=CC(C)c1cc(C)ccc1OC(C)=O,,O,,,,test
US20150284391A1,CI.COc1ccc2c(Cl)nc(O)cc2c1>>COc1ccc2c(Cl)nc(OC)cc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090312383A1,CCC(CC)c1ccc(C)c2nc(Cl)n(C)c12.COc1cc(Cl)cc(C)c1N>>CCC(CC)c1ccc(C)c2nc(Nc3c(C)cc(Cl)cc3OC)n(C)c12,,O,,CN1CCCC1=O,,test
US20100305096A1,CC(C)(C)OC(=O)N1CC(N2CCC(O)CC2)C1>>OC1CCN(C2CNC2)CC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US06002008,COc1cc2ncc(C#N)c(Cl)c2cc1OC.Nc1cccnc1>>COc1cc2ncc(C#N)c(Nc3cccnc3)c2cc1OC,,CCOCCO,,Cl,c1ccncc1,test
US20100130545A1,CNC(=O)CCc1cnc2occc2c1>>CNCCCc1cnc2occc2c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US07163938B2,O=C(O)c1ccccc1NC(=O)N1CCC2(CC1)OCCO2>>O=c1oc(N2CCC3(CC2)OCCO3)nc2ccccc12,,CN(C)C=O,,CCN=C=NCCCN(C)C,Cl,test
US20100004331A1,CCOC(=O)Cc1ccc(OC)c(Oc2ccc(NC(=O)c3ccc(Cl)cc3)cc2CSCC(F)(F)F)c1>>COc1ccc(CC(=O)O)cc1Oc1ccc(NC(=O)c2ccc(Cl)cc2)cc1CSCC(F)(F)F,,CO,O,[Li+].[OH-],,test
US20060173018A1,CC(C)(C)OC(=O)N1CCNC[C@@H]1COCc1ccccc1.Cc1ccc2c(Cl)nc(-c3ccccc3O)nc2c1>>Cc1ccc2c(N3CCN(C(=O)OC(C)(C)C)[C@@H](COCc4ccccc4)C3)nc(-c3ccccc3O)nc2c1,,CCN(CC)CC,CN(C)C=O,,,test
US20070244131A1,COc1nc(NCCc2ccc(C(F)(F)F)cc2F)cc(-c2cccc(O)c2)n1.ClCC1CO1>>COc1nc(NCCc2ccc(C(F)(F)F)cc2F)cc(-c2cccc(OCC3CO3)c2)n1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070270311A1,CC(=O)OC(C)=O.CCC(CO)Nc1c(-c2c(F)cc(F)cc2F)c(Cl)nc2ncnn12>>CCC(COC(C)=O)Nc1c(-c2c(F)cc(F)cc2F)c(Cl)nc2ncnn12,,ClCCl,,CCN(CC)CC,,test
US20140228340A1,CC(C)(C)c1cc(N)on1.N#Cc1cc(-c2ccnc(F)c2)ccc1OC1CCOCC1>>CC(C)(C)c1cc(Nc2cc(-c3ccc(OC4CCOCC4)c(C#N)c3)ccn2)on1,,C1COCCO1,,CC(C)(C)[O-].[K+],,test
US20070232583A1,O=S(=O)(Cl)c1cccc(-c2cc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)(F)F)n3)ccn2)c1.OCCNCCO>>O=S(=O)(c1cccc(-c2cc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)(F)F)n3)ccn2)c1)N(CCO)CCO,,C1CCOC1,,CCN(CC)CC,Cl,test
US20060128807A1,COC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)cc1OC>>COc1cc(OS(=O)(=O)C(F)(F)F)ccc1C(=O)O,,O,,CC(=O)O,O=S(=O)(O)O,test
US20130267546A1,COCOCCCCCCCCCCc1cc(OC)nc(N(C)C)n1.O=C1CCC(=O)N1Br>>COCOCCCCCCCCCCc1nc(N(C)C)nc(OC)c1Br,,CC#N,,,,test
US20150353581A1,Cc1cc(OCC(C)(N)C#N)c(C)c2c1COB2O.O=C(O)c1ccc(OC(F)(F)F)cc1>>Cc1cc(OCC(C)(C#N)NC(=O)c2ccc(OC(F)(F)F)cc2)c(C)c2c1COB2O,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050033049A1,COC(=O)c1cccc2[nH]c(C(=O)OC(C)(C)C)cc12>>COC(=O)c1cccc2[nH]c(C(=O)O)cc12,,O=C(O)C(F)(F)F,,Cc1ccccc1,,test
US20100137299A1,CCOC(=O)Cl.O=C1Nc2ccccc2C12COc1cc3c(cc12)OCCO3>>CCOC(=O)N1C(=O)C2(COc3cc4c(cc32)OCCO4)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20150353499A1,COc1ccc(Br)cc1CO.CS(=O)(=O)Cl>>COc1ccc(Br)cc1COS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20040082767A1,COC(=O)[C@@]12O[C@@H](CN=[N+]=[N-])[C@@H](O)C1OC(C)(C)O2>>COC(=O)[C@@]12O[C@@H](CN)[C@@H](O)C1OC(C)(C)O2,,CO,,,,test
US07256198B2,CC1(C)CN=C2N(C1)c1ccc(C#N)cc1C21OCCCO1>>CC1(C)CN=C2C(=O)c3cc(C#N)ccc3N2C1,,CS(=O)(=O)O,,[NH4+].[OH-],,test
US20020161269A1,Clc1ccccc1.O=[N+]([O-])O>>O=[N+]([O-])c1ccccc1Cl,,O,,,,test
US20130041007A1,Cc1ccc(S(=O)(=O)n2c3c(c4c(Cl)c(Cl)ccc42)CCC3(O[Si](C)(C)C)C(F)(F)F)cc1>>OC1(C(F)(F)F)CCc2c1[nH]c1ccc(Cl)c(Cl)c21,,C1CCOC1,O,[K+].[OH-],,test
US06165672,C1CCOC1.CC(=O)[O-].CC(C)(C)OC(=O)C1CC2C=CC1C2.CCC12C=CC(CC1C(=O)OO)C2.O=C(O)C1CC2C=CC1C2>>CC(=O)[O-].CC(C)(C)OC(=O)C1CC2C=CC1C2.O=C(O)C1CC2C=CC1C2.O=C(OCCO)C1CC2C=CC1C2,,C1CCOC1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20120208815A1,CCOC(=O)c1nc(Cl)ncc1N>>Nc1cnc(Cl)nc1C(=O)O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20160235734A1,COC(=O)c1ccc(CN(C[C@H](O[Si](C)(C)C(C)(C)C)c2ccc(OCc3ccccc3)c3[nH]c(=O)ccc23)C(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)N(Cc1ccc(C(=O)O)cc1)C[C@H](O[Si](C)(C)C(C)(C)C)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12,,CO,,[Na+].[OH-],,test
US20160024095A1,Cc1ccc(S(=O)(=O)Nc2cnccn2)cc1.NC(=O)CI.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1cn2ccncc2n1)C(F)(F)F,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,O,test
US20030055085A1,C=[N+]=[N-].Fc1ccc(-c2noc(-c3cc(F)cc(-c4nnn[nH]4)c3)n2)nc1>>Cn1nnnc1-c1cc(F)cc(-c2nc(-c3ccc(F)cn3)no2)c1,,C1CCOC1,,,,test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4c(Br)cccc4nn23)CC1.Cn1nccc1B1OC(C)(C)C(C)(C)O1>>Cn1nccc1-c1cccc2nn3c(C4CCN(C(=O)OC(C)(C)C)CC4)cc(=O)[nH]c3c12,,C1CCOC1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US04889858,CCOC(=O)c1cccc(F)c1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1cccc(F)c1CBr,,ClC(Cl)(Cl)Cl,,,,test
US20160052884A1,COCCC(C(=O)O)(n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O)C(C)(C)C>>COCCC(C(=O)O)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140179668A1,CC(C)c1cc(N)n[nH]1.Clc1nc(Cl)c2c(n1)CCC2>>CC(C)c1cc(Nc2nc(Cl)nc3c2CCC3)n[nH]1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20120108572A1,BrCc1ccccc1.O=C(O)c1ccc(Cl)c(O)c1>>O=C(O)c1ccc(Cl)c(OCc2ccccc2)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050245503A1,O=C1c2ccccc2CCc2ccc(Cl)cc21>>OC1c2ccccc2CCc2ccc(Cl)cc21,,CO,,[BH4-].[Na+],,test
US20130065900A1,NCc1cccc(Cl)c1.O=[N+]([O-])c1ccc(CCBr)c(Cl)c1>>O=[N+]([O-])c1ccc(CCNCc2cccc(Cl)c2)c(Cl)c1,,CS(C)=O,,O,,test
US20050148627A1,CCOC(=O)C1=Cc2c(ccc(Cl)c2N=[N+]=[N-])OC1C(F)(F)F>>CCOC(=O)C1=Cc2c(ccc(Cl)c2N)OC1C(F)(F)F,,CO,,,,test
US20150057277A1,Brc1ccc2ncc(N3CCOCC3)nc2c1.CC(C)(C)C(=O)Nc1ccc(O)cc1>>CC(C)(C)C(=O)Nc1ccc(Oc2ccc3ncc(N4CCOCC4)nc3c2)cc1,[Cu]I,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110077240A1,CCOC(=O)Cl.NS(=O)(=O)C1CC1>>CCOC(=O)NS(=O)(=O)C1CC1,,CC(C)=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20130123235A1,COC(=O)c1c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)ccc(-c2c(CO[Si](C)(C)C(C)(C)C)oc([Si](C)(C)C)c2F)c1O>>COC(=O)c1c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)ccc(-c2c(F)coc2CO)c1O,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080004267A1,CCc1csc([C@@H](N)Cc2ccc([N+](=O)[O-])cc2)n1.O=C=NCc1ccccc1>>CCc1csc([C@H](Cc2ccc([N+](=O)[O-])cc2)NC(=O)NCc2ccccc2)n1,,ClCCl,,Br,CCN(CC)CC,test
US20090253681A1,CC(C)(C)OC(=O)NC(COCc1ccccc1)/C(N)=N\O.COC(=O)C#CC(=O)OC.O=C(OC(=O)c1ccccc1)c1ccccc1>>COC(=O)c1nc(C(COCc2ccccc2)NC(=O)OC(C)(C)C)nc(O)c1OC(=O)c1ccccc1,,ClC(Cl)Cl,,,,test
US20150239837A1,CC(=O)c1cn(CC(=O)OC(C)(C)C)c2ccc(O)cc12>>CC(=O)c1cn(CC(=O)O)c2ccc(O)cc12,,C1COCCO1,Cl,,,test
US20110212053A1,CC(C)(C#N)c1ccc(C(=O)Cl)cc1.Cc1ccc(S(=O)(=O)n2ccc3cc(Br)ccc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(C(=O)c3ccc(C(C)(C)C#N)cc3)c3cc(Br)ccc32)cc1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20080167368A1,CC(=O)NCC(=O)c1ccc([N+](=O)[O-])nc1.N#CCC#N>>N#Cc1c(-c2ccc([N+](=O)[O-])nc2)c[nH]c1N,,CO,,[K+].[OH-],,test
US20150266857A1,O=S(=O)(c1ccccc1)n1cc(-c2ccc3cn[nH]c3c2)c2ccc(F)cc21>>Fc1ccc2c(-c3ccc4cn[nH]c4c3)c[nH]c2c1,,CO,O,[Na+].[OH-],,test
US20030166658A1,CC(=O)c1ccccn1.NNc1nc2ccccc2[nH]1>>CC(=NNc1nc2ccccc2[nH]1)c1ccccn1,CC(=O)O,CO,,,,test
US20110152247A1,COS(=O)OCCNc1nc2ccccc2o1.O=Cc1ccc(O)cc1>>O=Cc1ccc(OCCNc2nc3ccccc3o2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20020013460A1,CCN1CCN(c2nc(-c3ccc(OC)cc3)cc3ccccc23)CC1>>CCN1CCN(c2nc(-c3ccc(O)cc3)cc3ccccc23)CC1,,Br,,,,test
US20110092423A1,Cn1ncc(Cl)c1-c1ncc(C(=O)N[C@@H](Cc2cccc(F)c2)CN2C(=O)c3ccccc3C2=O)s1>>Cn1ncc(Cl)c1-c1ncc(C(=O)N[C@H](CN)Cc2cccc(F)c2)s1,,C1CCOC1,CO,NN,,test
US20100298321A1,Brc1nccs1.COC(=O)C1CCNCC1>>COC(=O)C1CCN(c2nccs2)CC1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110112070A1,CCOc1ncc(-c2cc(NC(=O)c3csc(C)n3)c3cn[nH]c3c2)cc1NS(=O)(=O)c1ccccc1>>Cc1nc(C(=O)Nc2cc(-c3cnc(O)c(NS(=O)(=O)c4ccccc4)c3)cc3[nH]ncc23)cs1,,O,,CC(=O)O,Cl,test
US04167508,CC(C)(C)Oc1ccc(CCC(=O)OCc2ccc([N+](=O)[O-])cc2)cc1>>CC(C)(C)Oc1ccc(CCC(=O)O)cc1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20100063078A1,CC(=O)O.COc1cc2c(cc1Cl)CCC2(C#N)CC#N.O=S(=O)(O)O>>COc1cc2c(cc1Cl)CCC21CC(=O)NC1=O,,O=S(=O)(O)O,,O,,test
US07160901B2,CC(=O)N(CCNC(=O)C(F)(F)F)c1ccc([N+](=O)[O-])cc1>>CC(=O)N(CCNC(=O)C(F)(F)F)c1ccc(N)cc1,[Pd],CO,,[H][H],,test
US20140322195A1,CN(C)C(OC(C)(C)C)N(C)C.COc1ccc(CN(Cc2ccc(OC)cc2)c2cc(C)c(C#N)cn2)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2cc(/C=C/N(C)C)c(C#N)cn2)cc1,,CN(C)C=O,,,,test
US20160108027A1,C=CCI.CC1OCCN(Cc2ccccc2)C1=O>>C=CCC1(C)OCCN(Cc2ccccc2)C1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04826532,CC(C)C(=O)CC(=O)OC(C)(C)C.N>>CC(C)C(N)=CC(=O)OC(C)(C)C,,CO,,,,test
US04062869,CC(C)OC(=O)C(=O)c1c[nH]c2ccccc12>>OCCc1c[nH]c2ccccc12,,CC(C)O,O,Cl,[BH4-].[Li+],test
US04146721,CCOC(=O)CC(C(C)=O)C(=O)c1ccccc1.NNc1ccccc1>>Cc1nn(-c2ccccc2)c(-c2ccccc2)c1CC(=O)O,,CCCCO,,Cl,,test
US20090163512A1,Cc1ccc(F)cc1C1NC(=O)CC(c2cc(Cl)ccc2OC2(C(=O)O)CCC2)C12C(=O)Nc1cc(Cl)ccc12.NS(=O)(=O)c1ccc(F)cc1>>Cc1ccc(F)cc1C1NC(=O)CC(c2cc(Cl)ccc2OC2(C(=O)NS(=O)(=O)c3ccc(F)cc3)CCC2)C12C(=O)Nc1cc(Cl)ccc12,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,[H-].[Na+],test
US04162329,NNc1ccc(C(F)(F)F)c(Cl)c1.O=C1C=CC(=O)O1>>NN(C(=O)/C=C\C(=O)O)c1ccc(C(F)(F)F)c(Cl)c1,,Cc1ccccc1,,,,test
US20080255111A1,CCB(CC)CC.COc1ccc(CC#N)cc1Br>>CCc1cc(CC#N)ccc1OC,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100009975A1,O=C(Cl)CCl.O=[N+]([O-])c1ccc2c(c1)OCCN2>>O=C(CCl)N1CCOc2cc([N+](=O)[O-])ccc21,,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US20050250836A1,COCCCn1c(C=O)cc2c1CC(c1ccccc1Cl)C1C(=O)NC(=O)C21>>COCCCn1c(C=O)cc2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O,O=[Mn]=O,C1COCCO1,,,,test
US20090069408A1,Nc1cccc(CO)c1Sc1ccc(F)cc1CO>>OCc1cccc2c1sc1c(CO)cc(F)cc12,[Cu],O=S(=O)(O)O,,O=N[O-].[Na+],,test
US05082954,CCCCCCCCCCCCC(O)c1coc([Si](CC)(CC)CC)c1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CCCCCCCCCCCCC(N=[N+]=[N-])c1coc([Si](CC)(CC)CC)c1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US06180629B2,NO.O=C(O)c1ccccc1C(=O)c1ccccc1>>O=c1onc(-c2ccccc2)c2ccccc12,,c1ccncc1,,Cl,Cl,test
US20020143186A1,CCOC(=O)C(O)CNC(=O)c1ccc(C(NC(=O)Nc2cc(Cl)cc(Cl)c2)c2ccc(C3=CCCCC3)cc2)cc1>>O=C(Nc1cc(Cl)cc(Cl)c1)NC(c1ccc(C(=O)NCC(O)C(=O)O)cc1)c1ccc(C2=CCCCC2)cc1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US03983111,CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)CN5CCOCC5)[C@@]4(C)CC(=O)[C@@H]32)C[C@@H]1O.O=P(O)(O)O>>CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)CN5CCOCC5)[C@@]4(C)CC(=O)[C@@H]32)C[C@@H]1O.O=P(O)(O)O,,CCO,O,,,test
US20050124656A1,CC(C)(C)OC(=O)c1ccc(Br)cc1.Cc1ccc(-c2ccccc2B(O)O)cc1>>Cc1ccc(-c2ccc(C(=O)OC(C)(C)C)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US04582841,C=CCN1C(=O)C(O)SC1=NN=C1SCC(=O)N1C.CN1CCOP1(=O)Cl>>C=CCN1C(=O)C(OP2(=O)OCCN2C)SC1=NN=C1SCC(=O)N1C,,ClCCl,,CCN(CC)CC,,test
US20090099213A1,Clc1ncnc2nc[nH]c12.NC(=O)C1CCNCC1>>NC(=O)C1CCN(c2ncnc3[nH]cnc23)CC1,,CCCCO,,CCN(CC)CC,,test
US20090105249A1,C=O.CC(C)CC(N)CC(=O)N1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1>>CNC(CC(=O)N1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1)CC(C)C,,CCOC(C)=O,CO,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04139545,COc1cc(C)c(C(=O)CCCCCCCCC(=O)O)c(OC)c1OC.OO>>COC1=C(OC)C(=O)C(CCCCCCCCCC(=O)O)=C(C)C1=O,,CC(=O)O,,O,,test
US20160244410A1,COc1ccc(CNC(=O)c2c(Oc3cccc(O[C@H]4CCOC4)c3C)cc(=O)n(C)c2Nc2ccc(I)cc2F)cc1>>Cc1c(Oc2cc(=O)n(C)c(Nc3ccc(I)cc3F)c2C(N)=O)cccc1O[C@H]1CCOC1,,COc1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20070185089A1,COC(=O)c1cnc(N2CCC(c3ccc4c(c3)CCN(C3CCC3)CC4)CC2)cn1>>O=C(O)c1cnc(N2CCC(c3ccc4c(c3)CCN(C3CCC3)CC4)CC2)cn1,,ClCCl,,Cl,,test
US20080312226A1,COc1cccc2onc(N(C(=O)OCC(Cl)(Cl)Cl)C(=O)OCC(Cl)(Cl)Cl)c12.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>COc1cccc2onc(NC(=O)N3CCN(c4nc(-c5ccccc5)ns4)CC3)c12,,O,,CCN(C(C)C)C(C)C,CS(C)=O,test
US04661602,Cc1ccccc1S(=O)(=O)OCCn1ccnc1.Clc1ccc(N2CCN=C2Cc2ccccc2)c(Cl)c1>>Clc1ccc(N2CCN=C2C(CCn2ccnc2)c2ccccc2)c(Cl)c1,,C1CCOC1,,[Li]CCCC,,test
US20100152165A1,COC(=O)c1ccc2c(c1)N(c1ccccc1)C(=O)CC2>>O=C(O)c1ccc2c(c1)N(c1ccccc1)C(=O)CC2,,CO,,C1CCOC1,[Na+].[OH-],test
US06245713B1,O=C(O)CNCP(=O)(O)O>>O=C(O)CNCP(=O)(O)O,,O,,CC(C)O,,test
US06335360B1,CO.O=C(O)c1cc2c(F)cccc2[nH]1>>COC(=O)c1cc2c(F)cccc2[nH]1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20070004786A1,CCn1cc(C#Cc2cccc(OC)c2)cc1C(=O)Cl.CN(C)O>>CCn1cc(C#Cc2cccc(OC)c2)cc1C(=O)NC,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20120142922A1,COC(=O)c1ccc(N=C=S)cc1.COCCNc1ccc(-c2ccccc2)cc1[N+](=O)[O-]>>COCCn1c(Nc2ccc(C(=O)OC)cc2)nc2cc(-c3ccccc3)ccc21,,C1CCOC1,CCOC(C)=O,CCN=C=NCCCN(C)C,,test
US20140274914A1,COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)NS(=O)(=O)C6CC6)C[C@H]5C=CCCCCC[C@H](CC(=O)N5CCCC(F)(F)C5)C(=O)N4C3)cc(-c3nc(C(C)C)cs3)nc2c1C>>COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)NS(=O)(=O)C6CC6)C[C@H]5C=CCCCCC[C@H](CC(=O)N5CCCC(F)(F)C5)C(=O)N4C3)cc(-c3nc(C(C)C)cs3)nc2c1C,,O,,[Na],,test
US20020032219A1,CCOC(=O)c1sc2ccc(Cl)cc2c1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1sc2ccc(Cl)cc2c1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20090163471A1,COC(=O)c1cccc(OC)c1C#CCCO>>COc1cccc(C(=O)O)c1C#CCCO,,CO,O,Cl,[K+].[OH-],test
US20140171435A1,CO.CS(=O)(=O)c1ccc(Br)c(F)c1>>COc1cc(S(C)(=O)=O)ccc1Br,,CO,,C[O-].[Na+],,test
US20120101124A1,CCOC(=O)CCc1ccc(-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)c2cc[nH]c12>>CC(C)Oc1ccc(-c2nc(-c3ccc(CCC(=O)O)c4[nH]ccc34)no2)cc1Cl,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20070049607A1,Cc1cc([N+](=O)[O-])ccn1.O=C1CCC(=O)N1Br>>O=[N+]([O-])c1ccnc(CBr)c1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US06943184B2,CN(C(=O)OC(C)(C)C)C1(/C=C\c2cccnc2)CC1>>CN(C(=O)OC(C)(C)C)C1(CCc2cccnc2)CC1,[Pd],CO,,,,test
US20110237791A1,CC(C)OB(OC(C)C)OC(C)C.O=S(=O)(c1ccc(Br)cc1Cl)C1CC1>>O=S(=O)(c1ccc(B(O)O)cc1Cl)C1CC1,,C1CCOC1,,Cl,[Li]CCCC,test
US20070299051A1,Cc1cc(C(=O)O)cc2c1Oc1c(Cl)cc([N+](=O)[O-])cc1CS2(=O)=O>>Cc1cc(C(=O)O)cc2c1Oc1c(Cl)cc(N)cc1CS2(=O)=O,[Ni],CN(C)C=O,,,,test
US20020193382A1,C=C[Sn](CCCC)(CCCC)CCCC.CC(C)(C)OC(=O)N1CCC(CN2CCN(S(=O)(=O)c3ccc(Br)s3)CC2=O)CC1>>C=Cc1ccc(S(=O)(=O)N2CCN(CC3CCN(C(=O)OC(C)(C)C)CC3)C(=O)C2)s1,,C1COCCO1,,[Cl-].[Li+],,test
US20160194304A1,CC(C)(C)OC(=O)Nc1ccc(OCc2ccccc2)cc1.CCI>>CCN(C(=O)OC(C)(C)C)c1ccc(OCc2ccccc2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20030013720A1,CN(CC1(c2ccc(I)cc2)CCN(C(=O)OC(C)(C)C)CC1)C(=O)Nc1cc(Cl)cc(Cl)c1>>CN(CC1(c2ccc(I)cc2)CCNCC1)C(=O)Nc1cc(Cl)cc(Cl)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150183801A1,CC1(C)OB(c2cncc(F)c2)OC1(C)C.O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(Cl)c(I)c1>>O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(Cl)c(-c2cncc(F)c2)c1,,ClCCl,,CCCCCC,,test
US20110040092A1,C=CCCCCCCCCCC.O>>CCCCCCCCCCC1CO1,,CC#N,,ClCCl,,test
US20110136802A1,COc1ccc2c(c1)SC[C@H]1[C@@]2(C)CC[C@H]2C(C)(C)CCC[C@@]21C>>CC1(C)CCC[C@@]2(C)[C@H]1CC[C@@]1(C)c3ccc(O)cc3SC[C@@H]12,,ClCCl,,BrB(Br)Br,,test
US20030158188A1,COC(=O)Cl.O=[N+]([O-])c1cccc2[nH]ncc12>>COC(=O)n1ncc2c([N+](=O)[O-])cccc21,,CN(C)C=O,,O,[H-].[Na+],test
US20110009399A1,COCCCN1CCOc2ccc(CO[C@H]3CN(C(=O)OC(C)(C)C)CC[C@]3(O)c3ccc(Cl)cc3CCO)cc21>>COCCCN1CCOc2ccc(CO[C@H]3CNCC[C@]3(O)c3ccc(Cl)cc3CCO)cc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130303533A1,CC(C)Br.Fc1ccc(Sc2nc(Cl)c3cc[nH]c3n2)cc1>>CC(C)n1ccc2c(Cl)nc(Sc3ccc(F)cc3)nc21,,CN(C)C=O,O,[H-].[Na+],,test
US06235771B1,NC(=O)C1=Cc2ccccc2S(=O)(=O)CC1.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>NC(=O)C1=Cc2ccccc2S(=O)(=O)CC1.O=C(O)[C@H](O)[C@@H](O)C(=O)O,,C1CCOC1,,,,test
US20110021537A1,CCOC(=O)N1CCN(C(=O)[C@H](CC2COC(C)(C)O2)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)NC3CCC3)n(-c3ccccc3)n2)CC1>>CCOC(=O)N1CCN(C(=O)[C@H](CC(O)CO)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)NC3CCC3)n(-c3ccccc3)n2)CC1,,CO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20070213331A1,CCCN(C)C(=O)c1cc(C(=O)OC)cc(C(=O)c2ccccc2)c1.SCCCS>>CCCN(C)C(=O)c1cc(C(=O)OC)cc(C2(c3ccccc3)SCCCS2)c1,,ClCCl,,CCOCC,FB(F)F,test
US06124283,CN1CCN(c2cccc3c2C[C@H](N)CC3)CC1.O=C(O)c1ccc(-c2ccc(O)cc2)cc1>>CN1CCN(c2cccc3c2C[C@H](NC(=O)c2ccc(-c4ccc(O)cc4)cc2)CC3)CC1,,ClCCl,O=S(Cl)Cl,CCN(CC)CC,,test
US20080139561A1,CC(=O)c1ccc(F)nc1.NO>>CC(=NO)c1ccc(F)nc1,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20150105317A1,[N-]=[N+]=NCCC[C@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>NCCC[C@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,[Pd],CO,,,,test
US20060009453A1,Cc1cc(N)ccc1O.O=C(O)c1cccc(C(F)(F)F)c1>>Cc1cc(NC(=O)c2cccc(C(F)(F)F)c2)ccc1O,,ClCCl,,ClCCCl,,test
US20100179148A1,CCOC(=O)Cl.CCOC(=O)Nc1cccc(Cn2nc(-c3ccc(C(=N)NO)cc3)ccc2=O)c1>>CCOC(=O)Nc1cccc(Cn2nc(-c3ccc(-c4noc(=O)[nH]4)cc3)ccc2=O)c1,,CN(C)C=O,O,Cl,c1ccncc1,test
US20060052449A1,CN(C)CCCCN.O=C(O)c1ccc(-c2ccc(CSCCOc3ccccc3)cc2)cc1>>CN(C)CCCCNC(=O)c1ccc(-c2ccc(CSCCOc3ccccc3)cc2)cc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20130178486A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.COc1ccc(Cn2cnc3cc(Cl)ncc32)cc1>>C=C(OCC)c1cc2ncn(Cc3ccc(OC)cc3)c2cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN1CCCC1=O,,,,test
US20060057714A1,CCN(CC)C(=S)[S-].ClCc1ccccc1>>CCN(CC)C(=S)SCc1ccccc1,,O,,CCO,,test
US04727180,O=C(O)Cc1cccc(C(O)(C(F)(F)F)C(F)(F)F)c1>>OCCc1cccc(C(O)(C(F)(F)F)C(F)(F)F)c1,,C1CCOC1,,Cl,[H][H],test
US04762850,COC(=O)CCl.NCc1cc(F)cc(F)c1>>COC(=O)CNCc1cc(F)cc(F)c1,,CCOCC,CN(C)C=O,CCN(CC)CC,,test
US04084955,Brc1n[nH]c(Br)c1Br.CCCCC(Br)C(=O)OCC>>CCCCC(C(=O)OCC)n1nc(Br)c(Br)c1Br,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080171882A1,CC(C)(C)OC(=O)NCCCC1(CS(=O)(=O)N2CCC(Oc3ccc(Cl)cn3)CC2)NC(=O)NC1=O.O=C(O)C(F)(F)F>>NCCCC1(CS(=O)(=O)N2CCC(Oc3ccc(Cl)cn3)CC2)NC(=O)NC1=O.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20080027067A1,C[C@@H]1CNCCN1.O=S(=O)(Nc1ccncn1)c1ccc(Br)cc1>>C[C@@H]1CN(c2ccc(S(=O)(=O)Nc3ccncn3)cc2)CCN1,,Cc1ccccc1,,CC(C)(C)O[Na],,test
US20120270893A1,CC(C)(C)OC(=O)CBr.O=Cc1cc2cc(O)ccc2nc1Cl>>CC(C)(C)OC(=O)COc1ccc2nc(Cl)c(C=O)cc2c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20150158826A1,CC(C)(C)C(=O)Nc1cccc(C(=O)c2ccc3ncc(-c4cccnc4)nc3c2)c1>>Nc1cccc(C(=O)c2ccc3ncc(-c4cccnc4)nc3c2)c1,,CC(=O)O,,Cl,[Na+].[OH-],test
US20100184741A1,Nc1ccccc1CO.O=C(Cl)CCl>>O=C(CCl)Nc1ccccc1CO,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20140275152A1,CC(=O)N1CCC(CCl)=C(c2ccccc2)C1.O=Cc1c(O)cccc1O>>CC(=O)N1CCC(COc2cccc(O)c2C=O)=C(c2ccccc2)C1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20080188531A1,CC(=O)Nc1nc(C)c(-c2csc(C(=O)NCC3CCCO3)n2)s1.CC(C)(C)OC(=O)CN>>Cc1nc(NC(=O)NCC(=O)OC(C)(C)C)sc1-c1csc(CC#N)n1,,CN(C)C=O,,CCN(CC)CC,,test
US20100099681A1,CC1(C)C(=O)N(Br)C(=O)N1Br.COC(=O)c1cc(OC)ccc1Nc1cc(C)nn1-c1ccccc1OC>>COC(=O)c1cc(OC)ccc1Nc1c(Br)c(C)nn1-c1ccccc1OC,,ClCCl,,,,test
US08299074B2,Cc1ccc(-n2nc(C(C)(C)C)cc2N)cc1.Nc1ccc(Oc2ccnc(NC(=O)N3CCCC3)c2)c2ccccc12.O=C(n1ccnc1)n1ccnc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(NC(=O)N4CCCC4)c3)c3ccccc23)cc1,,ClCCl,,,,test
US04356186,C=CCO.CC(C(=O)O)c1ccc2c(c1)SCC1CCCCC1C2=O>>C=CCOC(=O)C(C)c1ccc2c(c1)SCC1CCCCC1C2=O,,O,,O=S(=O)(O)O,,test
US20160176868A1,C=CC(=O)c1cccc(OC)c1.CCOC(=O)CC#N>>CCOC(=O)C(C#N)CCC(=O)c1cccc(OC)c1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20120095022A1,O=C1c2cccc([N+](=O)[O-])c2C2CC3(CCN12)OCCO3>>Nc1cccc2c1C1CC3(CCN1C2=O)OCCO3,,CCO,,Cl[Sn]Cl,,test
US20040192692A1,CSc1nncc(-c2ccc(F)c(-c3ccc(F)cc3C#N)c2)n1.OB(O)c1ccc(F)cc1>>N#Cc1cc(F)ccc1-c1cc(-c2cnnc(-c3ccc(F)cc3)n2)ccc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,ClCCl,,,test
US20090105302A1,C=CC1CC1(NC(=O)C1CC(O[Si](C)(C)C(C)(C)C)CN1)C(=O)OCC.C=CCCCCCNCc1ccc(OC)cc1.O=C(Cl)Cl>>C=CCCCCCN(Cc1ccc(OC)cc1)C(=O)N1CC(O[Si](C)(C)C(C)(C)C)CC1C(=O)NC1(C(=O)OCC)CC1C=C,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20070099915A1,C[Si](C)(C)CCOCON1CCc2c(ncc3c2c(CCCN2CCOCC2)cn3Cc2ccc(F)cc2)C1=O.Cl>>Cl.O=C1c2ncc3c(c(CCCN4CCOCC4)cn3Cc3ccc(F)cc3)c2CCN1O,,CO,,C1COCCO1,,test
US20090130117A1,COCCCn1nnnc1-c1cc(Br)c(OCc2ccccc2)cc1OCc1ccccc1.OB(O)c1ccc(OC(F)(F)F)cc1>>COCCCn1nnnc1-c1cc(-c2ccc(OC(F)(F)F)cc2)c(O)cc1O,,CCO,,Cc1ccccc1,O=C([O-])O.[Na+],test
US20060128752A1,C=O.CN(Cc1cc(Br)cc(Br)c1)C(=O)CC1(c2ccc(F)c(F)c2)CCNCC1>>CN1CCC(CC(=O)N(C)Cc2cc(Br)cc(Br)c2)(c2ccc(F)c(F)c2)CC1,,CC#N,O,[Na],,test
US04864021,CC(=O)OC[C@H]1O[C@@H](n2cc(F)c(=O)[nH]c2=O)C[C@@H]1OCc1ccccc1.O=C(Cl)c1cccc(C(=O)Cl)c1.O=C(Oc1cc(=O)[nH]cc1Cl)c1ccccc1>>CC(=O)OC[C@H]1O[C@@H](n2cc(F)c(=O)n(C(=O)c3cccc(C(=O)Oc4cc(OC(=O)c5ccccc5)c(Cl)cn4)c3)c2=O)C[C@@H]1OCc1ccccc1,,C1COCCO1,,CCN(CC)CC,,test
US03950393,CCCC(=O)Cl.CCOC(=O)c1cc(Br)c(N)c(CN(CC)CC)c1>>CCCC(=O)Nc1c(Br)cc(C(=O)OCC)cc1CN(CC)CC,,c1ccccc1,,,,test
US20030022881A1,CSc1ncn2cc(C3=C(C(=O)OCc4ccc([N+](=O)[O-])cc4)N4C(=O)[C@H]([C@@H](C)O)[C@H]4[C@H]3C)sc12.O=C(CI)NOC(=O)OCc1ccc([N+](=O)[O-])cc1>>CSc1c2sc(C3=C(C(=O)OCc4ccc([N+](=O)[O-])cc4)N4C(=O)[C@H]([C@@H](C)O)[C@H]4[C@H]3C)c[n+]2cn1CC(=O)NOC(=O)OCc1ccc([N+](=O)[O-])cc1.[I-],,CC#N,,,,test
US20150057265A1,Cn1cc(-c2cnc3c(C(=O)Nc4cnccc4N4C[C@H](C(F)(F)F)C[C@H](NC(=O)OC(C)(C)C)C4)c(NC(=O)OC(C)(C)C)oc3c2)cn1>>Cn1cc(-c2cnc3c(C(=O)Nc4cnccc4N4C[C@H](C(F)(F)F)C[C@H](N)C4)c(N)oc3c2)cn1,,CO,,C1COCCO1,Cl,test
US20060111375A1,COc1cc2c(Oc3cc4cnccc4nc3C)ccnc2cc1O.OCCBr>>COc1cc2c(Oc3cc4cnccc4nc3C)ccnc2cc1OCCO,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04144341,C=CCBr.O=c1[nH]c2ccc(Cl)nc2n1-c1ccc2c(c1)OCO2>>C=CCn1c(=O)n(-c2ccc3c(c2)OCO3)c2nc(Cl)ccc21,,CC(C)=O,,[K+].[OH-],,test
US20060194969A1,CCOC(=O)c1cc(NCc2c(C)cccc2C)c2nc(C)n(OC)c2c1>>COn1c(C)nc2c(NCc3c(C)cccc3C)cc(C(=O)O)cc21,,C1COCCO1,,Cl,[Na+].[OH-],test
US20160272637A1,COc1cn(C(C[C@@H]2CCCCO2)C(=O)OC(C)(C)C)c(=O)cc1-c1cc(Cl)ccc1C#N>>COc1cn(C(C[C@@H]2CCCCO2)C(=O)O)c(=O)cc1-c1cc(Cl)ccc1C#N,,ClCCl,,O=C(O)C(F)(F)F,,test
US06022492,CCCCCCCCOc1ccc(-c2ncc(Br)cn2)cn1.CCCCCCCCc1ccc(B(O)O)c(F)c1F>>CCCCCCCCOc1ccc(-c2ncc(-c3ccc(CCCCCCCC)c(F)c3F)cn2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20090247514A1,CCO/C=C/C(=O)Cl.Nc1ccc2c(c1)CC1(C2)C(=O)Nc2ncccc21>>CCO/C=C/C(=O)Nc1ccc2c(c1)CC1(C2)C(=O)Nc2ncccc21,,ClCCl,c1ccncc1,,,test
US20140371278A1,O=S(=O)(Cl)C1CC1.O=c1[nH]c2cc3ocnc3c(F)c2n1-c1ccc(I)cc1F>>O=c1n(-c2ccc(I)cc2F)c2c(F)c3ncoc3cc2n1S(=O)(=O)C1CC1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US05260051,CCCCCCC(O)C(=O)O.CCCCCCCCCCO>>CCCCCCCCCCOC(=O)C(O)CCCCCC,O=S(=O)(O)O,,,,,test
US20090143444A1,CC1(C)OB(c2ccc(OC(F)F)cc2)OC1(C)C.CN(Cc1cc(Br)n(S(=O)(=O)c2cccnc2)c1)C(=O)OC(C)(C)C>>CN(Cc1cc(-c2ccc(OC(F)F)cc2)n(S(=O)(=O)c2cccnc2)c1)C(=O)OC(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090275573A1,CC(C)(C)OC(=O)N1CCCC1(C)CNCc1ccccc1Cl>>CC1(CNCc2ccccc2Cl)CCCN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04175135,CCOC(=O)CC(C)(C)CCC(C#N)c1ccc(C)cc1C.O>>Cc1ccc(C2C(=O)CC(C)(C)CC2=O)c(C)c1,,CCOCC,,CC(=O)O,Cl,test
US20020183319A1,O=C1Cc2c(ncnc2Nc2ccc(F)c(Cl)c2)N1.O=Cc1ccc(C(=O)N2CCOCC2)s1>>O=C1Nc2ncnc(Nc3ccc(F)c(Cl)c3)c2C1=Cc1ccc(C(=O)N2CCOCC2)s1,CCN(CC)CC,CCO,,,,test
US20080194617A1,CCOC(=O)Cl.Cc1nn(C)c(-n2ccc3cc(Cl)ccc32)c1CCS(N)(=O)=O>>CCOC(=O)NS(=O)(=O)CCc1c(C)nn(C)c1-n1ccc2cc(Cl)ccc21,,c1ccncc1,,Cl,,test
US20090069365A1,CCOC(=O)Cl.c1cc2c(s1)CC1CCNCC21>>CCOC(=O)N1CCC2Cc3sccc3C2C1,,ClCCl,,CCN(CC)CC,,test
US20040132727A1,COc1cc2nccc(Oc3ccc(N)c(F)c3)c2cc1OC.Cc1ccccc1C(=O)N=C=S>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4ccccc4C)c(F)c3)c2cc1OC,,Cc1ccccc1,,CCO,,test
US04442109,C=O.CS.Oc1ccnc2ccccc12>>CSCc1cnc2ccccc2c1O,,CC(C)O,,CCN(CC)CC,,test
US20060004017A1,BrCC1CO1.COc1cc2c(Oc3ccc4[nH]c(C)cc4c3)ncnc2cc1O>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3)ncnc2cc1OCC1CO1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120196864A1,COc1cc(/C=C2\SC(=O)NC2=S)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F.N>>COc1cc(/C=C2\SC(=O)N=C2N)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F,,CO,,,,test
US20080200501A1,CC(C)(C)C(=O)Cl.NNC(=O)c1nn(-c2ccc(F)cc2F)c2c1C1CCC2C1>>CC(C)(C)C(=O)NNC(=O)c1nn(-c2ccc(F)cc2F)c2c1C1CCC2C1,,ClCCl,,CCN(CC)CC,,test
US20070219234A1,COCC1CCCN(c2cc[nH]c(=S)c2C#N)C1.NC(=O)CCl>>COCC1CCCN(c2ccnc3sc(C(N)=O)c(N)c23)C1,,CCOC(C)=O,CN(C)C=O,O,[Na+].[OH-],test
US20020156081A1,COc1cc(-c2nn(C3CCN(C4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)OC(C)(C)C>>COc1cc(-c2nn(C3CCN(C4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1N,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100280029A1,COc1ncc(-c2cc(-c3ncc(CN4CCN(C(C)C)CC4)o3)c3cnn(S(=O)(=O)c4ccccc4)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F>>COc1ncc(-c2cc(-c3ncc(CN4CCN(C(C)C)CC4)o3)c3cn[nH]c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F,,CC(C)O,CO,[Na+].[OH-],,test
US20110144106A1,BrCc1ccncc1.O=C1Nc2ccccc2[C@@]12C[C@@H]2c1ccc(Cl)cc1>>O=C1N(Cc2ccncc2)c2ccccc2[C@@]12C[C@@H]2c1ccc(Cl)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US04777281,CCCC1(CCC(C)=O)CCc2cc(OC)c(Cl)c(Cl)c2C1=O>>CCCC12CCC(=O)C=C1c1c(cc(OC)c(Cl)c1Cl)CC2,,O,,CCO,[Na+].[OH-],test
US20030018034A1,C1CNCCN1.O=[N+]([O-])c1cnc(Br)s1>>O=[N+]([O-])c1cnc(N2CCNCC2)s1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US04820866,CC(C)C(Oc1ccc([N+](=O)[O-])cc1)C(C)(C)COc1ccc([N+](=O)[O-])cc1>>CC(C)C(Oc1ccc(N)cc1)C(C)(C)COc1ccc(N)cc1,[Ni],CN(C)C=O,,,,test
US09433623B2,O=C1CC(=O)NC(=O)N1.O=Cc1cc(Br)cc(Br)c1O>>O=C1NC(=O)C(=Cc2cc(Br)cc(Br)c2O)C(=O)N1,,CC(=O)O,,,,test
US20050065195A1,Brc1ccc(N(Cc2ccccc2)Cc2ccccc2)cc1.CC(C)OB(OC(C)C)OC(C)C>>OB(O)c1ccc(N(Cc2ccccc2)Cc2ccccc2)cc1,,O,,[Li]CCCC,,test
US20110190289A1,CN(C)c1cccc(B(O)O)c1.Fc1ccc(Oc2nn3c(I)cnc3s2)cc1>>CN(C)c1cccc(-c2cnc3sc(Oc4ccc(F)cc4)nn23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100286148A1,CN(C)C(=O)Cl.O=c1nc(-c2cc(C(F)(F)F)ccn2)[nH]o1>>CN(C)C(=O)n1c(-c2cc(C(F)(F)F)ccn2)noc1=O,,c1ccncc1,,C1CCC2=NCCCN2CC1,,test
US20160122341A1,Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(-c3cnn(CCOS(C)(=O)=O)c3)n2c1.O=S1(=O)CCNCC1>>Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(-c3cnn(CCN4CCS(=O)(=O)CC4)c3)n2c1,CN(C)c1ccncc1,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20100316601A1,CC1=NN(c2ccc3c(c2)CCCC3)C(=O)C1.COC(=O)c1ccc(-c2cccc(N)c2O)o1.O=N[O-]>>COC(=O)c1ccc(-c2cccc(NN=C3C(=O)N(c4ccc5c(c4)CCCC5)N=C3C)c2O)o1,,Cl,,O=C([O-])O.[Na+],,test
US20040165140A1,C1COCO1.CC(C)(C#N)N=NC(C)(C)C#N.N#Cc1ccc(-c2ccc(O)cc2)cc1.O=C1CCCCC1>>C=CC(=O)OCC.N#Cc1ccccc1-c1ccccc1.O=C(O)c1ccccc1,CC(C)(C#N)N=NC(C)(C)C#N,,,,,test
US20150175562A1,CCOC(=O)c1nc(CC2CCCCC2)c(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)s1.N>>CC(C)(C)c1cc(-c2sc(C(N)=O)nc2CC2CCCCC2)cc(C(C)(C)C)c1,,CO,,,,test
US20120270875A1,CCOCCOCCBr.Cc1nc(NCCCc2cccc(O)c2)nc(C)c1C(=O)N[C@@H](CNC(=O)c1cccs1)C(=O)O>>CCOCCOCCOC(=O)[C@H](CNC(=O)c1cccs1)NC(=O)c1c(C)nc(NCCCc2cccc(O)c2)nc1C,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,[I-].[Na+],test
US20080207654A1,CCCc1nc(C)n(-c2ccc(OC3CCC3)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCc1nc(C)n(-c2ccc(OC3CCC3)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US20080004271A1,N#Cc1c(Cl)ncnc1-c1cccc(NC(=O)Nc2ccc(C(F)(F)F)cc2)c1.NC(=O)CS>>N#Cc1c(SCC(N)=O)ncnc1-c1cccc(NC(=O)Nc2ccc(C(F)(F)F)cc2)c1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20090023924A1,COC(=O)c1c(OCc2c(F)cc(Br)cc2F)nsc1NC(=O)NCCCCN1CCCC1.N>>NC(=O)c1c(OCc2c(F)cc(Br)cc2F)nsc1NC(=O)NCCCCN1CCCC1,,C1CCOC1,CO,,,test
US05272134,Cc1ccc(S(=O)(=O)NN=C2CC[C@H]3[C@@H]4CCC5=CC(O)CC[C@]5(CO)[C@H]4CC[C@]23C)cc1>>C[C@@]12C=CC[C@H]1[C@@H]1CCC3=CC(O)CC[C@]3(CO)[C@H]1CC2,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20030134891A1,C=[N+]=[N-].CO.O=C(O)[C@H]1CCCN1C(=O)CCCCC(=O)N1CCC[C@@H]1C(=O)O>>COC(=O)[C@H]1CCCN1C(=O)CCCCC(=O)N1CCC[C@@H]1C(=O)OC,,C1CCOC1,,CCOCC,,test
US20110319380A1,CNC=O.O=C(O)c1ccc(Br)cc1[N+](=O)[O-]>>Cn1cnc2cc(Br)ccc2c1=O,,O,,,,test
US20090253917A1,CCOC(=O)C1(N(NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)CC(=O)NC1=O.Cl>>CCOC(=O)C1(NN)CC(=O)NC1=O.Cl,,CCOC(C)=O,,,,test
US20090062290A1,Cc1ccc(S(=O)(=O)N=c2ccc(F)cn2C(C(N)=O)c2ccccc2)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1nc2ccc(F)cn2c1-c1ccccc1)C(F)(F)F,,ClCCl,,,,test
US20150119385A1,COC(OC)c1nc2c(cc1CN1CCN(C)CC1=O)CCCN2.COCCNc1cc(N)ncc1C#N.O=C(n1cncn1)n1cncn1>>COCCNc1cc(NC(=O)N2CCCc3cc(CN4CCN(C)CC4=O)c(C(OC)OC)nc32)ncc1C#N,,CN(C)C=O,,,,test
US20120316193A1,BrBr.CC(=O)c1nc(-c2ccc(Cl)cc2)oc1C>>Cc1oc(-c2ccc(Cl)cc2)nc1C(=O)CBr,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20150299201A1,Cc1nnc2n1-c1ccc(OC(F)(F)F)cc1C(c1ccc(Cl)cc1)=C[C@H]2CC(=O)OC(C)(C)C>>Cc1nnc2n1-c1ccc(OC(F)(F)F)cc1C(c1ccc(Cl)cc1)=C[C@H]2CC(=O)O,,C1COCCO1,Cl,,,test
US05945382,Clc1cc(Cl)cc(-c2cc[nH]n2)c1.O=C1CCC(=O)N1I>>Clc1cc(Cl)cc(-c2n[nH]cc2I)c1,,ClCCl,,,,test
US05820785,C#Cc1ccc([C@@H]2CC[C@@H](CCCCC)CC2)cc1.CN(C)C=O>>CCCCC[C@@H]1CC[C@@H](c2ccc(C#CC=O)cc2)CC1,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US04820834,CN1C(=O)[C@@H](N)N=C(c2ccccc2)c2ccccc21.COc1cccc(N=C=O)c1>>COc1cccc(NC(=O)N[C@H]2N=C(c3ccccc3)c3ccccc3N(C)C2=O)c1,,C1CCOC1,,,,test
US20160075657A1,C[N+](=O)[O-].O=Cc1cccc(Br)c1OCC1CC1>>O=[N+]([O-])C=Cc1cccc(OCC2CC2)c1Br,,CC(=O)O,,C,O=C[O-].[NH4+],test
US20090306066A1,Cc1nc(Cl)c(F)c(N2CCN(C)C[C@@H]2C)n1.NN>>Cc1nc(NN)c(F)c(N2CCN(C)C[C@@H]2C)n1,,CS(C)=O,,O,,test
US20100168039A1,CC1(C)COC(CS[C@H]2C(=O)N(c3ccc(F)cc3)[C@@H]2c2ccc(OCC(=O)OC(C)(C)C)cc2)(c2ccc3c(c2)OCO3)OC1>>O=C(O)COc1ccc([C@@H]2[C@@H](SCC(=O)c3ccc4c(c3)OCO4)C(=O)N2c2ccc(F)cc2)cc1,,O=CO,,,,test
US05861417,COc1ccc(C(=O)[C@](O)(C(=O)O)[C@@](O)(C(=O)O)C(=O)c2ccc(OC)cc2)cc1.OCCC1(c2ccc(Cl)c(Cl)c2)CCNC1>>COc1ccc(C(=O)[C@](O)(C(=O)O)[C@@](O)(C(=O)O)C(=O)c2ccc(OC)cc2)cc1.OCC[C@@]1(c2ccc(Cl)c(Cl)c2)CCNC1,,CO,,O,,test
US20040122038A1,CCN1Cc2ccc(N)cc2-c2ccccc21.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCN1Cc2ccc(NC(=O)C(F)(F)F)cc2-c2ccccc21,,ClCCl,,c1ccncc1,,test
US20160046597A1,Cc1c([N+](=O)[O-])ccc2c1c(C1=CCN(C(=O)C3CCCC3)CC1)cn2C>>Cc1c(N)ccc2c1c(C1CCN(C(=O)C3CCCC3)CC1)cn2C,[Pd],CCO,,O=C[O-].[NH4+],,test
US20060079697A1,C[C@@]1(Cn2cc([N+](=O)[O-])nc2Cl)CO1.FC(F)(F)Oc1ccc(N2CCNCC2)cc1>>C[C@](O)(CN1CCN(c2ccc(OC(F)(F)F)cc2)CC1)Cn1cc([N+](=O)[O-])nc1Cl,,CN(C)C=O,,O,,test
US20120165347A1,CS(=O)(=O)OCc1cncc(Br)c1.OCC(F)(F)F>>FC(F)(F)COCc1cncc(Br)c1,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20070197620A1,Cc1cccc2c1C(c1ncc[nH]1)=CCO2>>Cc1cccc2c1C(c1ncc[nH]1)CCO2,[Pd],CCOC(C)=O,,,,test
US20080004325A1,COC(=O)CN(c1csc(-c2ccccc2)c1)S(N)(=O)=O>>O=C1CN(c2csc(-c3ccccc3)c2)S(=O)(=O)N1,,C1CCOC1,,[H-].[Na+],,test
US05908840,COC(=O)c1ccc(Br)cc1N.O=C(O)c1cccnc1Cl>>O=C(O)c1cccn2c(=O)c3ccc(Br)cc3nc12,Cl,O,,CCO,,test
US20110263647A1,CC(C)(C)OC(=O)N[C@H](CO)Cc1ccc(Cl)c(Cl)c1.O=S(Cl)Cl>>CC(C)(C)OC(=O)N1[C@@H](Cc2ccc(Cl)c(Cl)c2)COS1=O,,CC#N,,c1ccncc1,,test
US20160200725A1,CCN(CCn1c(=O)c(-c2c(Cl)c(OC)cc(OC)c2Cl)cc2cnc(NC)nc21)C1CCN(C(=O)OC(C)(C)C)CC1>>CCN(CCn1c(=O)c(-c2c(Cl)c(OC)cc(OC)c2Cl)cc2cnc(NC)nc21)C1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20090048259A1,CC(C)(C)OC(=O)OC(C)(C)C.C[C@H]1CN(c2nnc(Cl)c3ccccc23)CCN1>>C[C@H]1CN(c2nnc(Cl)c3ccccc23)CCN1C(=O)OC(C)(C)C,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20150087663A1,Cn1ncnc1-c1c(Cl)ncnc1Cl.N>>Cn1ncnc1-c1c(N)ncnc1Cl,,CO,,,,test
US04666915,CCOC(=O)c1cnc(SC)[nH]c1=O.Cc1ccc(C)c(N)c1>>CCOC(=O)c1cnc(Nc2cc(C)ccc2C)[nH]c1=O,,CCO,,,,test
US20070232583A1,COCCOCCOCCN.Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)Cl)c3)n2)n1>>COCCOCCOCCNS(=O)(=O)c1cccc(-c2cccc(-c3cc(-c4ccc(C(F)(F)F)cc4)cc(C)n3)n2)c1,,C1CCOC1,CCOC(C)=O,,,test
US20080312282A1,O=C(O)CBr.OC1(c2ccc(Br)cc2)CCCC1>>O=C(O)COC1(c2ccc(Br)cc2)CCCC1,,CN(C)C=O,,[H-].[Na+],,test
US20130345120A1,COc1cnc(NC(=O)[C@@H]2CCNN2C(=O)[C@H](CC2CCCC2)CN(C=O)OC2CCCCO2)nc1>>COc1cnc(NC(=O)[C@@H]2CCNN2C(=O)[C@H](CC2CCCC2)CN(O)C=O)nc1,,CC(=O)O,,O,,test
US04547507,CCCI.Cl.O=c1c2c(sc3ccccc13)CCNC2>>CCCN1CCc2sc3ccccc3c(=O)c2C1.Cl,,CCO,CO,CCN(CC)CC,ClCCl,test
US20080004251A1,Cc1cc(Cl)cc([N+](=O)[O-])c1.O=C1CCC(=O)N1Br>>O=[N+]([O-])c1cc(Cl)cc(CBr)c1,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20090131458A1,CC1(C)CC(CO)CCO1.CS(=O)(=O)Cl>>CC1(C)CC(COS(C)(=O)=O)CCO1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20120071461A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNC1CCN(Cc2ccccc2)CC1>>CN(C(=O)OC(C)(C)C)C1CCN(Cc2ccccc2)CC1,,ClCCl,,,,test
US03957850,CCI.CCOC(=O)Cc1ccc(N)cc1>>CCNc1ccc(CC(=O)OCC)cc1,,CC(C)O,,c1ccncc1,,test
US20110130401A1,CC(=O)OC(C)=O.N[C@@H]1c2ccccc2C[C@@H]1O>>CC(=O)N[C@@H]1c2ccccc2C[C@@H]1O,,ClCCl,,,,test
US05654458,CCC(=O)Cl.CCCCCCCCCCCCc1ccccc1>>CCCCCCCCCCCCc1ccc(C(=O)CC)cc1,,ClC(Cl)(Cl)Cl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US05990105,COc1cc(S)cc(OC)c1.Cc1cc(F)ccc1[N+](=O)[O-]>>COc1cc(OC)cc(Sc2ccc([N+](=O)[O-])c(C)c2)c1,,CN1CCCC1=O,,[K],,test
US20100152160A1,CC(C)(C)OC(=O)N1CCC(C#N)(C(O)c2ccc(F)cc2)CC1>>N#CC1(C(O)c2ccc(F)cc2)CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110190260A1,C[Si](C)(C)C#Cc1cccc2nc(NC(=O)C3CC3)nn12>>C#Cc1cccc2nc(NC(=O)C3CC3)nn12,,C1CCOC1,CC#N,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04792224,COCC1OCC(C)(C)[NH+]1C.O=Nc1c(O)ccc2ncccc12>>COC1=Nc2c(ccc3ncccc23)OC12OCC(C)(C)N2C,,c1ccccc1,,[I-].[K+],,test
US20090176786A1,CN(C(=O)NC1CCCCC1)c1ccc(SC(F)(F)F)cc1F.O=C(Cl)c1c(F)cccc1F>>CN(C(=O)N(C(=O)c1c(F)cccc1F)C1CCCCC1)c1ccc(SC(F)(F)F)cc1F,,Cc1ccccc1,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20120264735A1,CCN(CC)S(F)(F)F.Cn1cc(-n2ccc(=O)c(Cc3cccc(-c4ncc(OCC5(CO)COC5)cn4)c3)n2)cn1>>Cn1cc(-n2ccc(=O)c(Cc3cccc(-c4ncc(OCC5(CF)COC5)cn4)c3)n2)cn1,,ClCCl,,,,test
US20160046631A1,CC(C)(C)c1nc(Cl)c2nc[nH]c2n1.CC(C)n1nnnc1CCl>>CC(C)n1nnnc1Cn1cnc2c(Cl)nc(C(C)(C)C)nc21,,CN(C)C=O,,O,[H-].[Na+],test
US04284631,O=C(O)C1=CCS[C@@H]2C(NC(=O)C(=NOCc3ccc(F)cc3)c3csc(NC(=O)C(F)(F)F)n3)C(=O)N12>>Nc1nc(C(=NOCc2ccc(F)cc2)C(=O)NC2C(=O)N3C(C(=O)O)=CCS[C@H]23)cs1,,C1CCOC1,,O,CC(=O)[O-].[Na+],test
US20030195226A1,NO.O=Cc1ccc(F)cc1F>>ON=Cc1ccc(F)cc1F,,CCO,CO,Cl,O=C([O-])[O-].[K+].[K+],test
US04680297,CCCCC(O)Cc1c(O)c2cccnc2n(-c2ccccc2)c1=O>>CCCCC1Cc2c(c3cccnc3n(-c3ccccc3)c2=O)O1,,Br,,O,,test
US20150126490A1,CN1C[C@@H](c2ccc(Cl)c(F)c2)[C@H]([N+](=O)[O-])C1>>CN1C[C@@H](N)[C@H](c2ccc(Cl)c(F)c2)C1,[Zn],CO,,CC(=O)O,,test
US20100120841A1,Nc1ccccc1NC1CCN([C@@H]2CCCc3ccccc32)CC1.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2ccccc2n1C1CCN([C@@H]2CCCc3ccccc32)CC1,,C1CCOC1,,O,,test
US06020345,CI.c1cc(-c2cc[nH]n2)nc(C2OCCO2)c1>>Cn1ccc(-c2cccc(C3OCCO3)n2)n1,,CN(C)C=O,,[H-].[Na+],,test
US05756508,COc1ccncc1.C[Mg]Cl.O=C(Cl)OCc1ccccc1>>CC1CC(=O)C=CN1C(=O)OCc1ccccc1,,C1CCOC1,,,,test
US20030069233A1,COc1ccc(N)cc1N1CCN(Cc2ccccc2)CC1.Cc1c(S(=O)(=O)Cl)sc2ccc(Cl)cc12>>COc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N1CCN(CC2CC2)CC1,,CC(C)=O,,,,test
US20030220324A1,CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1C(=O)O.CN(C)Cc1ccccc1N1CCN(C(=O)[C@H](N)Cc2ccc(Cl)cc2)CC1>>CN(C)Cc1ccccc1N1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)OC(C)(C)C)CC1,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US05034370,C=O.CCC(C)c1ccc(O)c(C(=O)O)c1.Cc1ccccc1>>CCC(C)c1ccc(O)c(C(=O)O)c1.Cc1ccccc1C=O,,CC(=O)O,,O=S(=O)(O)O,,test
US20080188528A1,O=S(Cl)Cl.OCc1ccccc1Cc1ccccc1>>ClCc1ccccc1Cc1ccccc1,,ClCCl,,,,test
US05017604,CC(=O)c1cccc([N+](=O)[O-])c1C>>Cc1c(C(C)O)cccc1[N+](=O)[O-],,CO,O,[BH4-].[Na+],,test
US05244890,CON=C(C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(C[N+]3(C)CCN(C(=O)c4ccc(O)c(O)c4)CC3)CS[C@H]12)c1csc(NC=O)n1>>CON=C(C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(C[N+]3(C)CCN(C(=O)c4ccc(O)c(O)c4)CC3)CS[C@H]12)c1csc(N)n1,,CO,,Cl,O=C([O-])O.[Na+],test
US20120059030A1,CI.O=C(O)Cc1ccc(Cl)cc1>>CC(C(=O)O)c1ccc(Cl)cc1,,C1CCOC1,,[Li]CCCC,,test
US04990526,CCCc1c(OCCCSc2ccc(C(O)C(C)CC(=O)O)cc2)ccc(C(C)=O)c1O.CO>>CCCc1c(OCCCSc2ccc(C(O)C(C)CC(=O)OC)cc2)ccc(C(C)=O)c1O,,CO,,C1CCOC1,[Na+].[OH-],test
US20150080393A1,CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4ccc(Cl)cc4Br)C(F)(F)F)nc(N)n3)CC2)CN1C(=O)OC(C)(C)C.CS(=O)(=O)c1cccc(B(O)O)c1>>CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4ccc(Cl)cc4-c4cccc(S(C)(=O)=O)c4)C(F)(F)F)nc(N)n3)CC2)CN1C(=O)OC(C)(C)C,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20120270882A1,COC(O)C(F)(F)F.Cn1ccc(=O)c(O)c1>>Cn1ccc(=O)c(O)c1C(O)C(F)(F)F,,[Na+],[OH-],Cl,Cl,test
US06432982B1,COc1ccc(-c2cc3ccc(OC)cc3s2)cc1.COc1ccc(C(=O)O)cc1C#N>>COc1ccc(-c2sc3cc(OC)ccc3c2C(=O)c2ccc(OC)c(C#N)c2)cc1,CN(C)C=O,O=S(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20110201604A1,COCCNc1ccc(C(=O)OC)cc1[N+](=O)[O-]>>COCCNc1ccc(C(=O)OC)cc1N,[Pd],CCOC(C)=O,CO,,,test
US20130178478A1,CCOC(=O)c1nnc(Cl)cc1Cl.Cn1ccc2ccc(N)nc21>>CCOC(=O)c1nnc(Cl)cc1Nc1ccc2ccn(C)c2n1,,CC#N,,,,test
US06040309,CCOC(=O)c1sc2cc(CO)ccc2c1Cl.COc1cccc(S)c1>>CCOC(=O)c1sc2cc(CO)ccc2c1Sc1cccc(OC)c1,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20090105253A1,CCNC(=O)c1ccc(-n2nnc(C(=O)NC3CC3)c2CO)cc1.Oc1ccc(Br)cc1>>CCNC(=O)c1ccc(-n2nnc(C(=O)NC3CC3)c2COc2ccc(Br)cc2)cc1,,C1CCOC1,Cc1ccccc1,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20140051672A1,C=CCN.COc1cc(C(=O)O)ccc1-c1ccc(N(C)C2CC(C)(C)NC(C)(C)C2)nn1>>C=CCNC(=O)c1ccc(-c2ccc(N(C)C3CC(C)(C)NC(C)(C)C3)nn2)c(OC)c1,,CN(C)C=O,ClCCl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20040122006A1,COc1ccc(Sc2ccc3c(c2)OCC(=O)N3)cc1OC>>O=C1COc2cc(Sc3ccc(O)c(O)c3)ccc2N1,,ClCCl,,BrB(Br)Br,,test
US20040236109A1,CC(=O)N1c2ccc(NC(=O)CC(=O)O)cc2C(C)(c2ccccc2)CC1(C)C.COc1ccc(CN)cc1>>COc1ccc(CNC(=O)CC(=O)Nc2ccc3c(c2)C(C)(c2ccccc2)CC(C)(C)N3C(C)=O)cc1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090069326A1,COC(=O)c1ccc(B(O)O)cc1.O=C1[C@H](Cc2c(Cl)cc(OS(=O)(=O)C(F)(F)F)cc2Cl)CCN1C1CCC(F)(F)CC1>>COC(=O)c1ccc(-c2cc(Cl)c(C[C@@H]3CCN(C4CCC(F)(F)CC4)C3=O)c(Cl)c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20140114068A1,O=C1c2ccccc2C(=O)C1(O)O.Oc1ccc(F)cc1>>O=C1c2ccccc2C(=O)C1(O)c1cc(F)ccc1O,,CC(=O)O,,,,test
US03959322,C#CCCCc1ccc2c(c1)OCO2.C1COOOC1.CCNCC>>CCN(CC)CC#CCCCc1ccc2c(c1)OCO2,,C1COCCO1,,,,test
US05102877,C=CCOC(=O)N1CCC(O)(C#C[Si](C)(C)C)C1>>C=CCOC(=O)N1CC=C(C#C[Si](C)(C)C)C1,,c1ccncc1,,O,O=S(Cl)Cl,test
US20040106653A1,CC(C)[Si](Sc1ccc(C[C@@H](C)N(C[C@H](O)c2cccc(Cl)c2)C(=O)OC(C)(C)C)cc1)(C(C)C)C(C)C.COCOc1cccc(F)c1C=O>>COCOc1cccc(Sc2ccc(C[C@@H](C)N(C[C@H](O)c3cccc(Cl)c3)C(=O)OC(C)(C)C)cc2)c1C=O,,CN(C)C=O,,O,[Cs+].[F-],test
US20160206616A1,CCO.COC(=O)C1=C(CBr)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl.O=C(O)CC[C@@H]1CC(F)(F)CN1>>CCOC(=O)C1=C(CN2CC(F)(F)C[C@H]2CCC(=O)O)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US04092311,Clc1ccc(-c2ccc(Cl)nn2)cc1.NN>>NNc1ccc(-c2ccc(Cl)cc2)nn1,,CCCCO,,O,,test
US20080015187A1,COC(=O)c1nn2c(c1OCc1ccccc1)C(=O)NCC2.Fc1ccc(CBr)cc1>>COC(=O)c1nn2c(c1OCc1ccccc1)C(=O)N(Cc1ccc(F)cc1)CC2,,CN(C)C=O,,[H-].[Na+],,test
US20030114443A1,CC(=O)N1CCC(C(=O)Cl)CC1.CSc1ccccc1>>CSc1ccc(C(=O)C2CCN(C(C)=O)CC2)cc1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20110118322A1,COC(=O)c1cccc(COc2ccc(I)cc2)c1.OB(O)c1ccc(F)cc1F>>COC(=O)c1cccc(COc2ccc(-c3ccc(F)cc3F)cc2)c1,,C1COCCO1,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20070173530A1,Nc1ccc2cnccc2c1.O=C(Cl)CCc1ccccc1>>O=C(CCc1ccccc1)Nc1ccc2cnccc2c1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US06232290B1,BrCCCCCCCBr.Sc1ccc(Br)cc1>>BrCCCCCCCSc1ccc(Br)cc1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20060167055A1,O=[N+]([O-])c1ccc(Oc2ccc(Br)nc2)cn1>>Nc1ccc(Oc2ccc(Br)nc2)cn1,[Fe],CC(=O)O,,O,,test
US20060089375A1,CCOC(=O)c1cnc2c(cnn2CC)c1NC1CCOCC1>>CCn1ncc2c(NC3CCOCC3)c(C(=O)O)cnc21,,CCO,O,[Na+].[OH-],,test
US20080009491A1,CC12CC3CC(C)(C1)CC(N)(C3)C2.CCCCc1nc(C(=O)O)c2ccccn12.CCOC(C)=O.ClCCCl.On1nnc2ccccc21>>CC12CC3CC(C)(C1)CC(NC(=O)c1nc(CCN4CCOCC4)n4ccccc14)(C3)C2,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,Cl,test
US20110282056A1,CC(C)(C)OC(=O)NCc1ccccc1C#Cc1ccnc2[nH]ccc12>>NCc1ccccc1C#Cc1ccnc2[nH]ccc12,,CCOCC,CO,Cl,,test
US20090291971A1,CC(=O)c1ccc(B(O)O)cc1.Cn1ccc(On2nnc3cccnc32)nc1=O>>CC(=O)c1ccc(Oc2ccn(C)c(=O)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130059853A1,COC(=O)C(C)(C)CO.COc1ccc(-c2ccc3c(c2)COC3=O)c(O)c1OC>>COC(=O)C(C)(C)COc1c(-c2ccc3c(c2)COC3=O)ccc(OC)c1OC,,C1CCOC1,CCOC(C)=O,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100081653A1,Brc1cccnc1.CC1(C)OB(c2ccc(N)c([N+](=O)[O-])c2)OC1(C)C>>Nc1ccc(-c2cccnc2)cc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070088058A1,O=C(CCl)c1ccccc1.c1cn[nH]c1>>O=C(Cn1cccn1)c1ccccc1,,CC#N,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20100216746A1,C=Cc1cc(C#N)cc(Oc2c(Cl)ccc(CN)c2F)c1.C[Si](C)(C)CCOCn1cnc(Cl)c1C(=O)O>>C=Cc1cc(C#N)cc(Oc2c(Cl)ccc(CNC(=O)c3[nH]cnc3Cl)c2F)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040176433A1,CC(=O)C(=Cc1ccccc1C)c1ccncc1.OO>>CC(=O)C1(c2ccncc2)OC1c1ccccc1C,,CO,O,[Na+].[OH-],,test
US20140235658A1,C#Cc1cccc(Nc2ncnc3cc(OCC)c(N)cc23)c1.O=C(O)/C=C/CN1CCCCC1>>C#Cc1cccc(Nc2ncnc3cc(OCC)c(NC(=O)/C=C/CN4CCCCC4)cc23)c1,CN(C)C=O,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20100048636A1,CC(C)(C)OC(=O)N1CCC[C@@H](C(O)c2cccc(Cl)c2)C1.CCOC(=O)CCBr>>CCOC(=O)CCOC(c1cccc(Cl)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1,,CN(C)C=O,,[H-].[Na+],,test
US05434326,C=CC.C=CC.c1ccccc1>>CC(C)c1ccccc1,,c1ccccc1,,[Mg],,test
US06762205B1,COc1ccc(/C=C(\C#N)c2ccc(NS(N)(=O)=O)cc2)cc1>>N#C/C(=C\c1ccc(O)cc1)c1ccc(NS(N)(=O)=O)cc1,,ClCCCl,,,,test
US05158971,C[Si](C)(C)N=C=O.ONCc1ccc(CCCCCC(F)(F)F)s1>>NC(=O)N(O)Cc1ccc(CCCCCC(F)(F)F)s1,,C1COCCO1,,Cl,,test
US20120202785A1,CC(N)c1nc2ccc(F)c3c2n1CCO3.Clc1ncnc2c1ncn2C1CCCCO1>>CC(Nc1ncnc2c1ncn2C1CCCCO1)c1nc2ccc(F)c3c2n1CCO3,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20120288492A1,C1COCCN1.CSc1cnc(Cl)nc1Cl>>CSc1cnc(Cl)nc1N1CCOCC1,,CC(C)=O,,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US05011835,CCC(=O)Cl.Nc1nnc2c3c(c(N4CCOCC4)nn12)CCCC3>>CCC(=O)Nc1nnc2c3c(c(N4CCOCC4)nn12)CCCC3,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US04804394,C=O.O=C1COc2ccc([N+](=O)[O-])cc2N1>>O=C1COc2ccc([N+](=O)[O-])cc2N1CO,,O,,,,test
US04418073,CC(C)n1cc(O)cn1.CN(SN(C)C(=O)F)C(=O)F.CNC>>CC(C)n1cc(OC(=O)N(C)SN(C)C(=O)N(C)C)cn1,,Cc1ccccc1,,CCN(CC)CC,,test
US20120101086A1,Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(Cl)c3)s1)CCN(C(=O)OC(C)(C)C)C2>>Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(Cl)c3)s1)CCNC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US06100275,Cc1ccc(C2(O)CC3CCC(C2)N3C)cc1.O=C(O)/C=C/C(=O)O>>Cc1ccc(C2=CC3CCC(C2)N3C)cc1.O=C(O)/C=C/C(=O)O,,CCOCC,CO,CC(=O)O,Cl,test
US20100197681A1,NC1CCCOC1.O=C(Nc1nc2cccc(Cl)n2n1)c1ccccc1>>O=C(Nc1nc2cccc(NC3CCCOC3)n2n1)c1ccccc1,,CC(=O)N(C)C,,Cl,,test
US20090312338A1,Cc1ccc(S(=O)(=O)n2ccc3nc(NC(=O)OC(C)(C)C)cnc32)cc1.O=C(CBr)C1CCCCC1>>Cc1ccc(S(=O)(=O)n2ccc3nc(N(CC(=O)C4CCCCC4)C(=O)OC(C)(C)C)cnc32)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20160137617A1,NCCCCCCCC(=O)O.O=C(Cl)OCc1ccccc1>>O=C(O)CCCCCCCNC(=O)OCc1ccccc1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20030119807A1,CNC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1>>CNC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)O)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160272622A1,COS(=O)(=O)OC.Cc1sccc1-n1nn[nH]c1=O>>Cc1sccc1-n1nnn(C)c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20110009454A1,Cl.NO.O=Cc1cccc(Oc2ccc(C(F)(F)F)cc2)c1>>Cl.NCc1cccc(Oc2ccc(C(F)(F)F)cc2)c1,[Pd],CCO,O,Cl,[H][H],test
US04877795,CC(C)O.O=C(O)Cc1ccccn1>>CC(C)OC(=O)Cc1ccccn1,,Cl,,O=C([O-])O.[Na+],,test
US20120115894A1,CCOC(=O)[C@H]1C[C@@H]1c1ccc(-c2cn(C)cn2)cc1.O=C1CCC(=O)N1I>>CCOC(=O)[C@H]1C[C@@H]1c1ccc(-c2ncn(C)c2I)cc1,,ClCCl,,,,test
US20100056516A1,O=C(NCc1ccc(F)cc1)c1c(O)c2cccnc2n(OCc2ccccc2)c1=O>>O=C(NCc1ccc(F)cc1)c1c(O)c2cccnc2n(O)c1=O,,Br,,O,,test
US20140179666A1,CC(C)[Si](C(C)C)(C(C)C)N1CC(C)(C)c2cc(F)c(Br)cc21.O=S(=O)(F)c1ccccc1>>CC(C)[Si](C(C)C)(C(C)C)N1CC(C)(C)c2cc(F)c(S(=O)(=O)c3ccccc3)cc21,,C1CCOC1,,[Li]CCCC,,test
US20140194386A1,COC(=O)c1ccc2c(c1)N=C(SC)NC2.COc1ccc(CN)c(OC)c1>>COC(=O)c1ccc2c(c1)N=C(NCc1ccc(OC)cc1OC)NC2,,CC(C)(C)O,,,,test
US20160096827A1,Cc1cc(-c2ncnc(Nc3ccc(N4CCN(C5COC5)CC4)cc3)n2)cc(C#N)c1O[C@H]1CCN(C(=O)OC(C)(C)C)C[C@H]1F>>Cc1cc(-c2ncnc(Nc3ccc(N4CCN(C5COC5)CC4)cc3)n2)cc(C#N)c1O[C@H]1CCNC[C@H]1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120015907A1,C=CC(=O)OC.C=CCCN(c1nc2oc(-c3ccc(C)cc3)c(C(=O)NC)c2cc1C1CC1)S(C)(=O)=O>>CNC(=O)c1c(-c2ccc(C)cc2)oc2nc(N(CCC=CC(=O)OC)S(C)(=O)=O)c(C3CC3)cc12,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,ClCCl,,,,test
US04587047,CS(=O)(=O)NC(=O)N1C[C@H](NC(=O)OCc2ccccc2)C1=O.Cl>>CS(=O)(=O)NC(=O)N1C[C@H](N)C1=O.Cl,[Pd],CO,O,,,test
US20080070896A1,CNCCO.Cl.O=C(Oc1ccc([N+](=O)[O-])cc1)OC1CCN(c2nc(-c3cc(F)c(Cl)cc3F)nc3c2CS(=O)(=O)C3)CC1>>CN(CCO)C(=O)OC1CCN(c2nc(-c3cc(F)c(Cl)cc3F)nc3c2CS(=O)(=O)C3)CC1.Cl,,C1CCOC1,CN(C)C=O,C1COCCO1,O=C([O-])O.[Na+],test
US06414179B1,CC(C)(C)[Si](C)(C)Cl.COC(=O)CCc1ccc(O)cc1>>COC(=O)CCc1ccc(O[Si](C)(C)C(C)(C)C)cc1,,CN(C)C=O,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20090143429A1,CC[C@H](NC(=O)c1c(CC2CCNCC2)c(-c2ccccc2)nc2c(F)cccc12)c1ccccc1.O=C1CCOCC1>>CC[C@H](NC(=O)c1c(CC2CCN(C3CCOCC3)CC2)c(-c2ccccc2)nc2c(F)cccc12)c1ccccc1,,CC(=O)O,ClCCCl,Cl,O=C([O-])O.[Na+],test
US20060189681A1,COc1ccc(Br)cc1C(C)=O>>COc1ccc(Br)cc1[C@@H](C)O,,ClCCl,,,,test
US20050124656A1,CC(C)(C)OC(=O)c1cccc(-c2ccc(CBr)cc2)c1.N>>NCc1ccc(-c2cccc(C(=O)O)c2)cc1,,CO,,,,test
US20130123252A1,BrP(Br)Br.COC(=O)c1sc(C#CC(C)(C)C)cc1N1C(=O)[C@@H](O)CC[C@H]1C1CCCCC1>>COC(=O)c1sc(C#CC(C)(C)C)cc1N1C(=O)[C@@H](Br)CCC1C1CCCCC1,,ClCCl,,,,test
US20030105151A1,Cc1c(CCC(=O)O)c[nH]c1C=O.O=C1Cc2ccc(Br)cc2N1>>Cc1c(CCC(=O)O)c[nH]c1C=C1C(=O)Nc2cc(Br)ccc21,C1CCNCC1,CCO,,,,test
US20100331324A1,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.C[C@@]12C[C@H](O)[C@]3(CCO[C@H]4[C@@H]3[C@@H]1C(=O)N4c1ccc(C#N)c(C(F)(F)F)c1)O2>>COC(=O)/C=C1\C[C@@]2(C)O[C@@]13CCO[C@H]1[C@@H]3[C@@H]2C(=O)N1c1ccc(C#N)c(C(F)(F)F)c1,,C1CCOC1,,,,test
US05420270,ClCc1ccc(Br)nc1.Clc1ccc2c(c1)NCc1ccccc1O2>>Clc1ccc2c(c1)N(Cc1ccc(Br)nc1)Cc1ccccc1O2,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US20070179130A1,Nc1ccc(Oc2ncnc3[nH]ccc23)c(F)c1.O=C(O)C1(C(=O)Nc2ccc(F)cc2)CC1>>O=C(Nc1ccc(F)cc1)C1(C(=O)Nc2ccc(Oc3ncnc4[nH]ccc34)c(F)c2)CC1,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040009995A1,CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(Br)c1.Cc1ccc(COCC(=O)OC(C)(C)C)cc1B1OC(C)(C)C(C)(C)O1.O=C(O)C(F)(F)F>>CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2COCC(=O)O)c1.O=C(O)C(F)(F)F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,ClCCl,O=C([O-])[O-].[Na+].[Na+],test
US04590195,CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1c1ccccc1Cl.O=C(NS(=O)(=O)Cl)c1ccco1>>CCOC(=O)C1=C(COCCNS(=O)(=O)NC(=O)c2ccco2)NC(C)=C(C(=O)OC)C1c1ccccc1Cl,,CCN(CC)CC,ClC(Cl)Cl,,,test
US04271164,CNC.Cc1ncc2cc(-c3c(Cl)cccc3Cl)c(N)nc2n1.O=C(n1ccnc1)n1ccnc1>>Cc1ncc2cc(-c3c(Cl)cccc3Cl)c(NC(=O)N(C)C)nc2n1,,ClCCCl,,CCN(CC)CC,Cl,test
US20020068747A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.Oc1cccc(I)c1>>CC(C)(C)[Si](Oc1cccc(I)c1)(c1ccccc1)c1ccccc1,,CN(C)C=O,,c1c[nH]cn1,,test
US04486592,CC(C)(C)OC(=O)CCC1(C(N)=O)c2ccccc2-c2ccccc21>>NC(=O)C1(CCC(=O)O)c2ccccc2-c2ccccc21,,O=C(O)C(F)(F)F,,,,test
US04085125,COC(=O)CCCCCCC(Br)C(=O)OC.CS>>COC(=O)CCCCCCC(C)C(=S)OC,,CO,,[Na],C[O-].[Na+],test
US20150266862A1,COC(=O)C1CCN(Cc2cccc(Oc3ccccc3)c2)C1>>O=C(O)C1CCN(Cc2cccc(Oc3ccccc3)c2)C1,,C1CCOC1,O,[Li+].[OH-],,test
US20100234351A1,BrCc1ccccc1.COc1ccc(OCC(C)O)cc1>>COc1ccc(OCC(C)OCc2ccccc2)cc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20040224952A1,CCOC(=O)CC(=O)Cl.Nc1cc(Br)ccc1S>>CCOC(=O)C1=C(O)Nc2cc(Br)ccc2S1,,c1ccncc1,,,,test
US04192871,C[C@@H]1C[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]2(C)[C@H]1C1(C)OCCO1>>C[C@@H]1C[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@H]1C1(C)OCCO1,c1ccncc1,CCO,O,CC(=O)O,[BH4-].[Na+],test
US20140039140A1,COc1ccc(C)cc1-n1c2ccccc2c2ccccc21>>Cc1ccc(O)c(-n2c3ccccc3c3ccccc32)c1,,ClCCl,,BrB(Br)Br,,test
US20060020146A1,CC(C)(C)C=O.[Li]CCCC>>CCCCC(O)C(C)(C)C,,C1CCOC1,CCCCCC,,,test
US20160039794A1,Nc1cc(Cl)ccc1[N+](=O)[O-].OB(O)c1ccc(N2CCOCC2)nc1>>Nc1cc(-c2ccc(N3CCOCC3)nc2)ccc1[N+](=O)[O-],,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20060160864A1,CCCCOCCOc1ccc(-c2ccc(N3CCCC3)c(/C=C/C(=O)OCC)c2)cc1>>CCCCOCCOc1ccc(-c2ccc(N3CCCC3)c(/C=C/C(=O)O)c2)cc1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20080214543A1,C1CCOC1.C[C@@H]1CN(c2ccc(C#N)c(C(F)(F)F)c2)[C@@H](C)CN1C(=O)Cl.N#Cc1ccc(C(F)(F)F)cc1N.O>>COc1cc(N2C[C@@H](C)N(C(=O)Nc3cc(C(F)(F)F)ccc3C#N)C[C@@H]2C)ccc1C#N,,O,,[H-].[Na+],,test
US20100063066A1,CC(C)(C)OC(=O)n1nc(Cl)c2c(N)cccc21.O=C1CCC(=O)N1Cl>>CC(C)(C)OC(=O)n1nc(Cl)c2c(N)ccc(Cl)c21,,CC#N,,,,test
US20100016282A1,C[C@H]1C(=O)N(CCCN2CCCCC2)CCN1C(=O)OC(C)(C)C>>C[C@@H]1NCCN(CCCN2CCCCC2)C1=O,,C1COCCO1,,Cl,,test
US20100137313A1,Cn1c(=O)oc2cc(S(=O)(=O)Cl)ccc21.N>>Cn1c(=O)oc2cc(S(N)(=O)=O)ccc21,,ClC(Cl)Cl,,C1CCOC1,,test
US20130281402A1,NOC1CCCCO1.O=C(Cl)CCCCCCBr>>O=C(CCCCCCBr)NOC1CCCCO1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20060240048A1,CC(C)[Mg]Cl.O=C(NCC1CCC1)c1ccc(Cl)nc1>>CC(C)c1cc(Cl)ncc1C(=O)NCC1CCC1,,C1CCOC1,,,,test
US20040019059A1,NN.O=C(Cl)c1ccc(C(=O)c2ccccc2)cc1>>NNC(=O)c1ccc(C(=O)c2ccccc2)cc1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100298316A1,C1CCNCC1.O=Cc1ccc2nc(N3CCN(C4CC4)CC3)sc2c1>>c1cc2nc(N3CCN(C4CC4)CC3)sc2cc1CN1CCCCC1,,C1CCOC1,CO,CC(=O)O,[BH3-]C#N.[Na+],test
US20150258074A1,COc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(Cl)nc(CBr)c12.C[N+]1([O-])CCOCC1>>COc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(Cl)nc(C=O)c12,,C1CCOC1,,,,test
US20080242655A1,CN.N#Cc1cnccc1Cl>>CNc1ccncc1C#N,,O,,CCOCC,,test
US20070049606A1,CN1CCn2c1nc(C(=O)NCc1ccc(F)cc1)c(OCc1ccccc1)c2=O>>CN1CCn2c1nc(C(=O)NCc1ccc(F)cc1)c(O)c2=O,[Pd],CCO,CCOC(C)=O,[H][H],,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4cccs4)nc(Cl)c3n2)cc1.Nc1ccc(N2CCOCC2)cc1>>c1csc(-c2nc(Nc3ccc(N4CCOCC4)cc3)c3[nH]ncc3n2)c1,C1COCCO1,CO,,Cl,,test
US20100009974A1,O=S1(=O)N=CN(CC2CC2)c2ccc(Cl)cc21>>O=S1(=O)NCN(CC2CC2)c2ccc(Cl)cc21,,CC(C)O,,[BH4-].[Na+],,test
US20060264438A1,CCOC(=O)N1CC(O)C2OC2C1.[N-]=[N+]=[N-]>>CCOC(=O)N1CC(O)C(N=[N+]=[N-])C(O)C1,,COCCO,,[Cl-].[NH4+],,test
US20130102776A1,O=Cc1c[nH]c2ccccc12.O=S(=O)(Cl)c1ccccc1Cl>>O=Cc1cn(S(=O)(=O)c2ccccc2Cl)c2ccccc12,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20110003815A1,CC(=O)c1ccc(-c2ccc(C3(c4ccc(OCc5ccccn5)cc4)CCC3)cc2)nn1.C[Mg]Br>>CC(C)(O)c1ccc(-c2ccc(C3(c4ccc(OCc5ccccn5)cc4)CCC3)cc2)nn1,,C1CCOC1,CCOCC,Cc1ccccc1,,test
US20120316194A1,CCn1ccc2cnc(NC(=O)c3ccc([C@@](C)(O)CO)cc3)cc21.O=C1CCC(=O)N1Br>>CCn1cc(Br)c2cnc(NC(=O)c3ccc([C@@](C)(O)CO)cc3)cc21,,ClCCl,,,,test
US20110269712A1,CCOC(=O)Cn1nc(Cl)cc1Cl>>O=C(O)Cn1nc(Cl)cc1Cl,,C1CCOC1,O,[Na+].[OH-],,test
US20080027083A1,CCOC(=O)[C@@H]1CC2(CC[C@@H]1N1CC[C@H](NC(=O)OCc3ccccc3)C1=O)OCCO2>>CCOC(=O)[C@@H]1CC(=O)CC[C@@H]1N1CC[C@H](NC(=O)OCc2ccccc2)C1=O,,CC(C)=O,,Cl,,test
US20030092720A1,CC(C)c1csc(CCc2cc3nc(N4CCCC(C=O)C4)c(/C=C/C(=O)OC(C)(C)C)c(=O)n3cc2F)n1.CC(C)c1csc(COc2ccn3c(=O)c(/C=C/C(=O)OC(C)(C)C)c(N4CCCC(O)C4)nc3c2)n1>>CC(C)c1csc(CCc2cc3nc(N4CCCC(O)C4)c(/C=C/C(=O)OC(C)(C)C)c(=O)n3cc2F)n1,,CO,,O,C[O-].[Na+],test
US04532331,COc1ccc(Cn2ccnc2S)cc1>>COc1ccc(Cn2ccnc2)cc1,[Ni],CCO,,,,test
US20060264494A1,CC1(C)OCC(C(=O)N(CCOC2CCCCO2)[C@@H]2c3ccccc3C[C@H]2NC(=O)c2cc3cc(Cl)sc3[nH]2)O1>>O=C(N[C@@H]1Cc2ccccc2[C@H]1N(CCO)C(=O)C(O)CO)c1cc2cc(Cl)sc2[nH]1,,CC(=O)O,,,,test
US20040224997A1,CCCCOC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(-c2ccc(Nc3nc4ccc(OC)cc4s3)c(F)c2)cc1>>COc1ccc2nc(Nc3ccc(-c4ccc(C(=O)[C@@H]5CCC[C@H]5C(=O)O)cc4)cc3F)sc2c1,,CO,,[Na+].[OH-],,test
US04663327,CCOC(=O)C(=CO)c1ccccc1.NNc1ncccn1>>O=c1c(-c2ccccc2)c[nH]n1-c1ncccn1,,CCO,O,Cl,[Na+].[OH-],test
US20060030613A1,CC(C)(C)c1ccc(CNCCc2ccccc2)cc1.O=C(O)c1cc(F)cc2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCc2ccccc2)C(=O)c2cc(F)cc3cc[nH]c23)cc1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20090253907A1,Cc1ccc(C)c2c1C(=O)C(C)C2C.[Li]C>>CC1=C(C)C(C)c2c(C)ccc(C)c21,,CCOCC,,Cl,O,test
US20090197864A1,C[C@H](O)c1c(Cl)ccc(F)c1Cl.O=[N+]([O-])c1ncc2ccoc2c1O>>C[C@@H](Oc1c([N+](=O)[O-])ncc2ccoc12)c1c(Cl)ccc(F)c1Cl,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04889848,CCOC(=O)C(C(=O)OCC)=C1CSC2=C1SCCNC2>>CCOC(=O)C=C1CSC2=C1SCC=NC2,,CCO,,C[O-].[Na+],,test
US20050182091A1,CC(C)(C)[Si](C)(C)Cl.O=Cc1ccc(O)cc1Cl>>CC(C)(C)[Si](C)(C)Oc1ccc(C=O)c(Cl)c1,,CN(C)C=O,,c1c[nH]cn1,,test
US04835157,CC(=O)Cl.O=C(c1ccc(F)cc1)C1CCN(CCn2c(=O)[nH]c3sccc3c2=O)CC1>>CC(=O)n1c(=O)n(CCN2CCC(C(=O)c3ccc(F)cc3)CC2)c(=O)c2ccsc21,,ClCCl,,CCN(CC)CC,,test
US20070135457A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1ccc2nonc2c1>>O=S(=O)(Oc1ccc2nonc2c1)C(F)(F)F,CN(C)c1ccncc1,ClCCl,,,,test
US20130225588A1,COC(=O)Cc1cc2ccc(Cl)cc2c(B2OC(C)(C)C(C)(C)O2)c1C.Clc1ccc(Sc2ccc(Br)cc2)c(Cl)c1>>COC(=O)Cc1cc2ccc(Cl)cc2c(-c2ccc(Sc3ccc(Cl)cc3Cl)cc2)c1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])O.[Na+],test
US20160250211A1,Cc1cc(Nc2cc(C3CCCC3)[nH]n2)nc(Cl)n1.Nc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1>>Cc1cc(Nc2cc(C3CCCC3)[nH]n2)nc(Nc2ccc(C(=O)Nc3cccc(C(F)(F)F)c3)cc2)n1,,CCCCO,,Cl,,test
US20160120841A1,NC1CCOc2cc(Br)ccc21.O=C(O)C1(c2ccc3c(c2)OC(F)(F)O3)CC1>>O=C(NC1CCOc2cc(Br)ccc21)C1(c2ccc3c(c2)OC(F)(F)O3)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120289500A1,NOP(=O)(c1ccccc1)c1ccccc1.O=c1[nH]nc(N2CCOCC2)c2ccccc12>>Nn1nc(N2CCOCC2)c2ccccc2c1=O,,C1CCOC1,CCOC(C)=O,CC(C)(C)[O-].[K+],,test
US20030195232A1,CCS(=O)(=O)Cl.Nc1cnccc1CCCOc1cccnc1Oc1cccc(Cl)c1>>CS(=O)(=O)Nc1cnccc1CCCOc1cccnc1Oc1cccc(Cl)c1,,ClCCl,c1ccncc1,,,test
US20070249670A1,COC(=O)[C@H](C)N(Cc1ccccc1)C(=O)c1cc2ccccc2cc1N.O=C=Nc1c(Cl)cccc1Cl>>COC(=O)[C@H](C)N(Cc1ccccc1)C(=O)c1cc2ccccc2cc1NC(=O)Nc1c(Cl)cccc1Cl,,CN(C)C=O,,CCN(CC)CC,,test
US20130338081A1,COC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C.NN>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)NN,,CO,,O,,test
US20120202785A1,N#Cc1ccc([N+](=O)[O-])c(F)c1.Nc1ccccc1>>N#Cc1ccc([N+](=O)[O-])c(Nc2ccccc2)c1,,CS(C)=O,,,,test
US20040214841A1,COc1ccc(Br)c(Nc2ncnc3cccc(OCC4CCN(C(=O)OC(C)(C)C)CC4)c23)c1>>COc1ccc(Br)c(Nc2ncnc3cccc(OCC4CCNCC4)c23)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160009744A1,CC(C)(C)S(=O)/N=C(\c1cccc(Br)c1)c1csc(C2OCCO2)c1.[Li]C>>CC(C)(C)S(=O)N[C@](C)(c1cccc(Br)c1)c1csc(C2OCCO2)c1,,C1CCOC1,,CCOCC,,test
US20140275179A1,CCc1ccc(B(O)O)cc1.COC(=O)c1sc(C)cc1OS(=O)(=O)C(F)(F)F>>CCc1ccc(-c2cc(C)sc2C(=O)OC)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140155381A1,Cc1noc(C)c1C(O)c1cc2cc(CNC(=O)OC(C)(C)C)ccc2o1>>Cc1noc(C)c1C(O)c1cc2cc(CN)ccc2o1,,CO,,Cl,,test
US20080015203A1,CN(C)C(=O)c1ccc(F)c(F)c1.C[C@@H](CO)Oc1cc(O)cc(C(=O)Nc2ccn(C)n2)c1>>C[C@@H](CO)Oc1cc(Oc2ccc(C(=O)N(C)C)cc2F)cc(C(=O)Nc2ccn(C)n2)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20030158198A1,CC(=O)Nc1cc2c(N)cccc2cn1.O=C=NCc1ccc(C(F)(F)F)c(F)c1>>Nc1cc2c(NC(=O)NCc3ccc(C(F)(F)F)c(F)c3)cccc2cn1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20130336920A1,O=[N+]([O-])c1ccc(N2CCCCC2)cc1-c1cc(Oc2cccc(C(F)(F)F)c2)ncn1>>Nc1ccc(N2CCCCC2)cc1-c1cc(Oc2cccc(C(F)(F)F)c2)ncn1,[Pd],CCOC(C)=O,CO,,,test
US20060160879A1,CC(C)Oc1ccc(C(=O)Cl)cc1.CCCCc1ccc(-c2ccc3c(N)c(C(=O)OCC)n(Cc4cccc(Cl)c4)c3c2)cc1>>CCCCc1ccc(-c2ccc3c(NC(=O)c4ccc(OC(C)C)cc4)c(C(=O)OCC)n(Cc4cccc(Cl)c4)c3c2)cc1,CN(C)c1ccncc1,CC#N,,CCN(CC)CC,Cl,test
US20030013704A1,NCCSCCO.O=Cc1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1>>O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(CNCCSCCO)ccc1Cl,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05945382,Brc1cc(Br)cc(-c2cc[nH]n2)c1.O=S(=O)(Cl)Cl>>Clc1c[nH]nc1-c1cc(Br)cc(Br)c1,,ClCCCl,,c1ccncc1,,test
US05362480,CCCCCCCCCCN.OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O>>CCCCCCCCCCNC1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O,,CCOCC,CO,O,,test
US20080076924A1,Cc1ccccc1NC(=NC#N)N1CCNC(c2ccccc2)C1.O=C(Cl)Cc1ccc(Cl)cc1>>Cc1ccccc1NC(=NC#N)N1CCN(C(=O)Cc2ccc(Cl)cc2)C(c2ccccc2)C1,,ClCCl,,O,c1ccncc1,test
US07579352B2,CCC(CC)C(c1ccc(NC(=O)C2CCN(C(=O)[O-])C(C(C)(C)C)C2)cc1)n1ccnc1.Cl>>CCC(CC)C(c1ccc(NC(=O)C2CCNCC2)cc1)n1ccnc1.Cl,,CCOC(C)=O,,[Na+].[OH-],,test
US20080153837A1,O=C1c2ccccc2-c2c1cccc2C1=NC2CCCCC2N1>>O=C1c2ccccc2-c2c1cccc2-c1nc2c([nH]1)CCCC2,,CS(C)=O,,O,,test
US20070238723A1,CC(C)[C@]1(C(=O)O)CCC(=O)C1.CCN(CC)CC>>CC(C)C1(C(N)=O)CCC(=O)C1,CN(C)C=O,,,O=C(Cl)C(=O)Cl,,test
US20040132727A1,COc1cc2nccc(Oc3ccc(N)c(C)c3C)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OCCCOc1ccc(Cl)cc1>>COc1cc2nccc(Oc3ccc(NC(=O)OCCCOc4ccc(Cl)cc4)c(C)c3C)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20080119457A1,Cc1ncn2c1C(=O)CCC2.O=C1CCC(=O)N1Br>>Cc1nc(Br)n2c1C(=O)CCC2,,CC#N,,,,test
US20090247524A1,COc1ccccc1S.N#CCOc1cc(-c2nc(N)nc(S(=O)Cc3ccccc3)n2)c(Cl)cc1Cl>>COc1ccccc1Sc1nc(N)nc(-c2cc(OCC#N)c(Cl)cc2Cl)n1,,CN(C)C=O,,CCN(CC)CC,,test
US20140303378A1,N#CC(C#N)CC(=O)c1ccccc1.O=[N+]([O-])c1ccc(S)cc1>>N#Cc1cc(-c2ccccc2)[nH]c1Sc1ccc([N+](=O)[O-])cc1,,CO,,CCN(CC)CC,,test
US20120101110A1,COCc1cccc(-c2ocnc2C(=O)OC)c1>>COCc1cccc(-c2ocnc2CO)c1,,C1CCOC1,,[BH4-].[Li+],,test
US20050130997A1,COC(=O)c1nc(-c2sccc2N)n(C)c(=O)c1OC(=O)C(C)(C)C.O=CC=Cc1ccccc1>>COC(=O)c1nc(-c2sccc2NC/C=C/c2ccccc2)n(C)c(=O)c1OC(=O)C(C)(C)C,,ClCCCl,,CC(=O)O,O=C([O-])O.[Na+],test
US20130090334A1,CCN1N=C(c2cccnc2)CC1=O.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CCn1nc(-c2cccnc2)cc1OS(=O)(=O)C(F)(F)F,,C1CCOC1,,[H-].[Na+],,test
US20100016396A1,COc1ccc(COc2cc(Oc3c(C=O)cnn3C)c(Cl)cc2Cl)cc1.C[Si](C)(C)C[Mg]Cl>>C=Cc1cnn(C)c1Oc1cc(OCc2ccc(OC)cc2)c(Cl)cc1Cl,,C1CCOC1,,O,O=S(=O)(O)O,test
US20070066618A1,COC(=O)Cc1ccc(N)cc1Cl.Cc1cc(C)c([N+](=O)[O-])c(Cl)n1>>COC(=O)Cc1ccc(Nc2nc(C)cc(C)c2[N+](=O)[O-])cc1Cl,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20030087926A1,C=Cc1ccc(C)cc1.CCC(=O)C(=O)[O-].Nc1cc(Cl)cc(Cl)c1>>Cc1ccc(C2CC(C(=O)O)Nc3cc(Cl)cc(Cl)c32)cc1,,CC#N,CCO,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20070185171A1,N#Cc1ccnc2c1C(Br)(Br)C(=O)N2>>N#Cc1ccnc2c1CC(=O)N2,[Zn],CC#N,,CC(=O)O,,test
US04636506,O=[N+]([O-])c1ccc(F)c(-c2ccncc2)c1F>>Nc1ccc(F)c(-c2ccncc2)c1F,[Ni],CCO,,,,test
US20030027840A1,C=CC(=O)CC.CCCCC1Cc2cc(OC)ccc2C1=O>>CCCCC1(CCC(=O)CC)Cc2cc(OC)ccc2C1=O,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US05637579,C(Cc1ccccn1)=P(c1ccccc1)(c1ccccc1)c1ccccc1.C[C@@]1(C=O)S[C@@H]2CC(=O)N2[C@H]1C(=O)OC(c1ccccc1)c1ccccc1>>C[C@@]1(/C=C/c2ccccn2)S[C@@H]2CC(=O)N2[C@H]1C(=O)OC(c1ccccc1)c1ccccc1,,CCOCC,,ClCCl,,test
US05780642,N#Cc1ccc(OCCBr)cc1.O=C1NC(=O)c2ccccc21>>N#Cc1ccc(OCCN2C(=O)c3ccccc3C2=O)cc1,,CN(C)C=O,,[K],,test
US20080280917A1,COc1ccc2c(OC(C)COC(C)(C)C)ccnc2c1>>COc1ccc2c(OC(C)CO)ccnc2c1,,O=C(O)C(F)(F)F,,,,test
US20110105562A1,CC(C)(C)OC(=O)N[C@@H](Cc1cccs1)C(=O)NCCCC#Cc1cccc(OC2CCN(C(=O)OC(C)(C)C)CC2)c1.O=C(O)C(F)(F)F>>N[C@@H](Cc1cccs1)C(=O)NCCCC#Cc1cccc(OC2CCNCC2)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20130299805A1,CCCCCCC1(CCCCCC)c2cc(Br)ccc2-c2ccc(I)cc21.CCCC[Sn](CCCC)(CCCC)c1ccc(-c2ccc(OC)cc2)s1>>CCCCCCC1(CCCCCC)c2cc(Br)ccc2-c2ccc(-c3ccc(-c4ccc(OC)cc4)s3)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,[F-].[K+],,test
US20100286211A1,Nc1ccc(Br)cn1.O=C(Cl)c1ccc(F)cc1>>O=C(Nc1ccc(Br)cn1)c1ccc(F)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20040186132A1,O=[N+]([O-])c1ccc2c(c1)NCC2>>Nc1ccc2c(c1)NCC2,[Pd],CCOC(C)=O,,,,test
US20020091150A1,CCOC(N)=O.O=C(Cl)C1c2ccccc2Oc2ccccc21>>CCOC(=O)NC(=O)C1c2ccccc2Oc2ccccc21,CN(C)c1ccncc1,c1ccncc1,,,,test
US20100004235A1,COc1ccc(Cn2c(-c3nn(Cc4ccccc4F)c4ncccc34)nn(CC(F)(F)F)c2=O)c(OC)c1>>O=c1[nH]c(-c2nn(Cc3ccccc3F)c3ncccc23)nn1CC(F)(F)F,,CC(=O)O,,O=S(=O)(O)O,O=C([O-])[O-].[Na+].[Na+],test
US20150011527A1,C[C@@H](NC(=O)[C@H](Cc1ccc(-c2ncc(Br)cn2)cc1)NC(=O)c1ccc(C(C)(C)C)cc1)C(=O)OC(C)(C)C.OB(O)c1ccc(O)cc1>>C[C@@H](NC(=O)[C@H](Cc1ccc(-c2ncc(-c3ccc(O)cc3)cn2)cc1)NC(=O)c1ccc(C(C)(C)C)cc1)C(=O)OC(C)(C)C,,CC#N,O,C1CCOC1,O=C([O-])[O-].[Na+].[Na+],test
US20060178418A1,COc1ccc(C(=O)O)c2c3ccccc3n(Cc3ccc(F)cc3)c12.Nc1ccncc1>>COc1ccc(C(=O)Nc2ccncc2)c2c3ccccc3n(Cc3ccc(F)cc3)c12,CN(C)C=O,ClC(Cl)Cl,,CCN(CC)CC,O=S(Cl)Cl,test
US20140228340A1,CC(C)(C)OC(=O)N1CCC(n2ccc(Nc3cc(-c4ccc(OCC5CC5)c(C#N)c4)ccn3)n2)CC1>>N#Cc1cc(-c2ccnc(Nc3ccn(C4CCNCC4)n3)c2)ccc1OCC1CC1,,C1COCCO1,,Cl,,test
US20120035409A1,CC(C)C(N)=CC#N.CCOC(=O)CC(=O)COC(C)=O.Cc1n[nH]c2ccc(C=O)cc12>>Cc1n[nH]c2ccc(C3C(C#N)=C(C(C)C)NC4=C3C(=O)OC4)cc12,,CCCO,O,Cl,,test
US20040152699A1,Cn1c(SCc2noc(-c3cccc(Cl)c3)n2)nnc1-c1ccncc1.O=C(OO)c1cccc(Cl)c1>>Cn1c(SCc2noc(-c3cccc(Cl)c3)n2)nnc1-c1cc[n+]([O-])cc1,,ClCCl,,,,test
US20050014767A1,Nc1nc2cc(-c3ccc(C=C4SC(=O)NC4=O)cn3)cc(C34CC5CC(CC(C5)C3)C4)c2o1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C1NC(=O)C(=Cc2ccc(-c3cc(C45CC6CC(CC(C6)C4)C5)c4oc(NC(=O)C(F)(F)F)nc4c3)nc2)S1,,C1CCOC1,,c1ccncc1,,test
US20130338140A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C[C@@H](N)c1ccc(OC(F)F)cc1>>COC(=O)C[C@@H](NC(=O)OC(C)(C)C)c1ccc(OC(F)F)cc1,,ClCCl,,Cl,,test
US20080261941A1,CCOc1ccc(Oc2cccc(C=C3CCNCC3)c2)nc1.O=C(Nc1cccnn1)Oc1ccccc1>>CCOc1ccc(Oc2cccc(C=C3CCN(C(=O)Nc4cccnn4)CC3)c2)nc1,,CS(C)=O,O,CCN(CC)CC,,test
US20070298104A1,COc1ccc2oc(S)nc2c1.O=S(Cl)Cl>>COc1ccc2oc(Cl)nc2c1,CN(C)C=O,ClCCl,,,,test
US20070155813A1,COCCCC1C(c2ccccc2)=C(OCOC)C=C(OCOC)C1(Br)Br>>COCCCc1c(Br)c(O)cc(O)c1-c1ccccc1,,CCO,,Cl,,test
US20110257151A1,CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(N)c1)N2.O=C(Cl)N1CCCCC1>>CCOC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(NC(=O)N3CCCCC3)c1)N2,,ClCCl,,c1ccncc1,,test
US05117042,C1=COCCC1.CCCCCC(/C=C/[C@H]1[C@H](O)C[C@@H]2OC(=O)C[C@@H]21)O[Si](C)(C)C(C)(C)C>>CCCCCC(/C=C/[C@H]1[C@H](OC2CCCCO2)C[C@@H]2OC(=O)C[C@@H]21)O[Si](C)(C)C(C)(C)C,,ClCCl,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20060003998A1,CCOCC.Cl[Mg]c1ccccc1.N#CC1CN(Cc2ccccc2)CCO1>>O=C(c1ccccc1)[C@@H]1CN(Cc2ccccc2)CCO1,,Cc1ccccc1,,Cl,,test
US05158970,O=C1CC[C@@H](C(=O)O)N1.OC[C@@H]1CCCN1>>O=C1CC[C@@H](C(=O)N2CCC[C@H]2CO)N1,,ClCCl,,CCN(CC)CC,,test
US08741932B2,Cc1nc(N)ccc1Br.O=CC(Br)C=O>>Cc1c(Br)ccc2ncc(C=O)n12,,CC#N,,,,test
US20120252780A1,CO.Nc1nc(Cl)cnc1Br>>COc1ncc(Cl)nc1N,,CO,,C[O-].[Na+],,test
US20130115190A1,C=CCCC(C)C[C@H](CC)OS(=O)(=O)c1ccc(C)cc1.CCOC(=O)CN=C(c1ccccc1)c1ccccc1>>C=CCCC(C)C[C@@H](CC)C(N=C(c1ccccc1)c1ccccc1)C(=O)OCC,,Cc1ccccc1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20020025960A1,CCOC(=O)C(C(=O)[O-])[Si](C)(C)C.O=C(O)c1cc(I)ccc1F>>CCOC(=O)CC(=O)c1cc(I)ccc1F,,C1CCOC1,CC#N,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US20150344423A1,COC(=O)c1ccc(CC2CCCCC2)n1C(=O)OC(C)(C)C>>COC(=O)c1ccc(CC2CCCCC2)[nH]1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20070249686A1,CC(C)(C)OC(=O)/C=C/c1ccc(Cl)cc1-c1ccccc1>>O=C(O)CCc1ccc(Cl)cc1-c1ccccc1,[Pd],CCO,CCOC(C)=O,,,test
US20100298339A1,C[C@@H](O)CNC(=O)OC(C)(C)C.Oc1ccc(Br)cc1>>C[C@@H](CNC(=O)OC(C)(C)C)Oc1ccc(Br)cc1,,Cc1ccccc1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020004513A1,COc1ccc(CC(=O)Cl)cc1.COc1ccc(CNC2CCN(C(=O)OC(C)(C)C)CC2)cc1OC>>COc1ccc(CC(=O)N(Cc2ccc(OC)c(OC)c2)C2CCN(C(=O)OC(C)(C)C)CC2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20020193269A1,CC/C=C\CCO.O=C1CCC(=O)O1>>CCC=CCCOC(=O)CCC(=O)O,CN(C)c1ccccn1,CCOCC,ClCCl,Cl,c1ccncc1,test
US20150344423A1,Cc1c(S(=O)(=O)CC2CC2)cc(C(=O)O)n1CC1CCCCC1>>Cc1c(S(=O)(=O)CC2CC2)ccn1CC1CCCCC1,,CCO,Cl,,,test
US05036086,CC(=O)OCC(=O)Nc1nc2cc(C)c(C)cc2s1>>Cc1cc2nc(NC(=O)CO)sc2cc1C,,CO,,N,,test
US20100216746A1,CC(F)(F)c1cc(C#N)cc(Oc2c(Cl)ccc(CNC(=O)c3c(Cl)ncn3COCC[Si](C)(C)C)c2F)c1>>CC(F)(F)c1cc(C#N)cc(Oc2c(Cl)ccc(CNC(=O)c3[nH]cnc3Cl)c2F)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040186160A1,CS(=O)(=O)c1ccc2c(c1)CC(=O)N2.O=Cc1[nH]c2c(c1CCC(=O)O)CCCCC2>>CS(=O)(=O)c1ccc2c(c1)/C(=C/c1[nH]c3c(c1CCC(=O)O)CCCCC3)C(=O)N2,,CCO,,C1CCNCC1,,test
US05206240,COc1ccc2c(c1)C(=O)CC1(CCNCC1)O2.Cn1c(Cl)cc(=O)n(C)c1=O.NCCCl>>COc1ccc2c(c1)C(=O)CC1(CCN(NCCc3cc(=O)n(C)c(=O)n3C)CC1)O2,,CC#N,,Cl,O=C([O-])O.[Na+],test
US06960598B2,Clc1ccc2c(Cl)ccnc2n1.OB(O)c1ccccc1F>>Fc1ccccc1-c1ccc2c(Cl)ccnc2n1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20140213554A1,CC(C)(C)OC(=O)Nc1cnc2c(c1)cc(I)n2S(=O)(=O)c1ccccc1.Cl>>Cl.Nc1cnc2c(c1)cc(I)n2S(=O)(=O)c1ccccc1,,C1COCCO1,CC#N,,,test
US20120282546A1,BrC1CCCCC1.Oc1cccc(O)c1>>Oc1ccccc1OC1CCCCC1,,CN(C)C=O,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US20100120761A1,Fc1ccc(-c2ccn3ccnc3c2)cc1.Nc1cncc(Br)c1>>Nc1cncc(-c2cnc3cc(-c4ccc(F)cc4)ccn23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,N#N,O=C([O-])[O-].[K+].[K+],test
US04686224,CCOC(=O)OCC.O=C1Cc2cccc(C(=O)c3ccccc3)c2N1>>CCOC(=O)C1C(=O)Nc2c(C(=O)c3ccccc3)cccc21,,CN(C)C=O,,[H-].[Na+],,test
US20140031360A1,Cc1ccc(S(=O)(=O)Cl)cc1.Fc1ccccc1-c1ccc2[nH]cc(I)c2n1>>Cc1ccc(S(=O)(=O)n2cc(I)c3nc(-c4ccccc4F)ccc32)cc1,,C1CCOC1,CCOC(C)=O,[Na+].[OH-],,test
US20100144712A1,C[C@@H](N1CCN(c2nc3ccc(N)cc3s2)CC1)[C@](O)(Cn1cncn1)c1ccc(F)cc1F.ClCCN1CCOCC1>>C[C@@H](N1CCN(c2nc3ccc(NCCN4CCOCC4)cc3s2)CC1)[C@](O)(Cn1cncn1)c1ccc(F)cc1F,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US06358665B1,C1CCOC1.CC(C)(C)Oc1ccc(Cl)cc1.CC(C)(C)Oc1ccc(S(=O)c2ccc(OC(C)(C)C)cc2)cc1.C[Si](C)(C)OS(=O)(=O)C(F)(F)C(F)C(F)(F)F.c1ccncc1>>CCCCOc1ccc([S+](c2ccc(OCCCC)cc2)c2ccc(OCCCC)cc2)cc1.O=S(=O)([O-])C(F)(F)C(F)C(F)(F)F,,O,,[Mg],,test
US20140088078A1,CCN1CC[C@H](CN)C1.O=C(O)c1c(NS(=O)(=O)c2ccccc2F)ccc2c1OCC1CC21>>CCN1CC[C@H](CNc2ccccc2S(=O)(=O)Nc2ccc3c(c2C(=O)O)OCC2CC32)C1,,CS(C)=O,,CCN(CC)CC,,test
US20160052912A1,CC(C)(C)[Si](C)(C)OC(C#N)C#N.CCOc1cc(F)c(Cn2nc(C(=N)N)c3ccccc32)c(F)c1>>CCOc1cc(F)c(Cn2nc(-c3nc(N)c(O)c(N)n3)c3ccccc32)c(F)c1,,CC(C)(C)O,O,Cl,CC(C)(C)[O-].[K+],test
US20090286767A1,CC(=O)OC(C)=O.CCOC(=O)c1ncc(-c2ncccc2C(F)(F)F)cc1N>>Oc1cc(O)c2ncc(-c3ncccc3C(F)(F)F)cc2n1,,Cc1ccccc1,c1ccncc1,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20150266857A1,CS(=O)(=O)N1CCNCC1.O=S(=O)(c1ccccc1)n1cc(-c2ccc3nc(CCCl)oc3c2)c2ccc(F)cc21>>CS(=O)(=O)N1CCN(CCc2nc3ccc(-c4c[nH]c5cc(F)ccc45)cc3o2)CC1,,CO,,[Na+].[OH-],,test
US04788206,O=C(O)/C=C/C=C(c1ccc(-c2ccccc2)cc1)c1ccc(-c2ccccc2)cc1.O=[N+]([O-])c1ccc(O)cc1>>O=C(/C=C/C=C(c1ccc(-c2ccccc2)cc1)c1ccc(-c2ccccc2)cc1)Oc1ccc([N+](=O)[O-])cc1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20090324581A1,CCOC(=O)c1c[nH]nc1C(F)(F)F.IC1CCCC1>>CCOC(=O)c1cn(C2CCCC2)nc1C(F)(F)F,,O,,CN(C)C=O,[H-].[Na+],test
US20100022515A1,CS(=O)(=O)N1CCc2c(cc(F)c(OCc3ccccc3)c2F)C1>>CS(=O)(=O)N1CCc2c(cc(F)c(O)c2F)C1,[Pd],CCO,CCOC(C)=O,,,test
US03954789,C=[N+]=[N-].Cn1c(C=O)cnc1[N+](=O)[O-]>>CC(=O)c1cnc([N+](=O)[O-])n1C,,CCOCC,,,,test
US20100216746A1,COC(=O)c1[nH]cnc1Br>>O=C(O)c1[nH]cnc1Br,,CO,,Cl,[Na+].[OH-],test
US05344927,Cn1cc(C(=O)C2CCc3nc[nH]c3C2)c2ccccc21.O=C(O)C(O)(C(=O)c1ccccc1)C(O)(C(=O)O)C(=O)c1ccccc1>>Cn1cc(C(=O)[C@@H]2CCc3nc[nH]c3C2)c2ccccc21.O=C(O)C(O)(C(=O)c1ccccc1)C(O)(C(=O)O)C(=O)c1ccccc1,,CO,,,,test
US20090099190A1,CCOC(=O)C(=O)OCC.Cc1cc(F)ccc1Br>>CCOC(=O)C(=O)c1ccc(F)cc1C,,C1CCOC1,,[Li]CCCC,,test
US04604390,CCN(CC)CCn1nc2c3c(c(N)ccc31)Sc1ccccc1-2.O=C(Cl)CCl>>CCN(CC)CCn1nc2c3c(c(NC(=O)CCl)ccc31)Sc1ccccc1-2,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20090036492A1,Cc1cc(N)cc(C)c1C=O.O=S(=O)(Cl)c1ccccc1>>Cc1cc(NS(=O)(=O)c2ccccc2)cc(C)c1C=O,,ClCCl,c1ccncc1,[Cl-].[NH4+],,test
US20070203229A1,CNC(=O)c1ccccc1OC[C@@H]1CO1.NC1CCC2(CC1)Cc1cc(Cl)ccc1O2>>CNC(=O)c1ccccc1OC[C@@H](O)CNC1CCC2(CC1)Cc1cc(Cl)ccc1O2,,CCO,,,,test
US20020183361A1,CC[C@H](C)[C@@H](C=O)NS(=O)(=O)c1ccc(Cl)s1.C[Si](C)(C)C(F)(F)F>>CC[C@H](C)[C@H](NS(=O)(=O)c1ccc(Cl)s1)C(O)C(F)(F)F,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080318975A1,CCO.Cc1ccc2ccc(Cl)c(CC(=O)OC(C)(C)C)c2n1>>CCOC(=O)Cc1c(Cl)ccc2ccc(C)nc12,,CCO,Cl,,,test
US20060094767A1,C[C@](O)(COC(=O)N1CCN(N=Cc2ccc(C(F)(F)F)cc2)CC1)Cn1cc([N+](=O)[O-])nc1Cl>>C[C@]1(COC(=O)N2CCN(N=Cc3ccc(C(F)(F)F)cc3)CC2)Cn2cc([N+](=O)[O-])nc2O1,,CN(C)C=O,,[H-].[Na+],,test
US20100048554A1,CN(C)C1(CC2CCCC2)CCC2(CC1)OCCO2>>CN(C)C1(CC2CCCC2)CCC(=O)CC1,,O=S(=O)(O)O,,,,test
US04752645,C=CC[C@@H]1C(=O)N(CCN(C)C)c2ccccc2C[C@@H]1c1ccc(OC)cc1.Cl>>CCC[C@@H]1C(=O)N(CCN(C)C)c2ccccc2C[C@@H]1c1ccc(OC)cc1.Cl,[Pd],,,,,test
US07294636B2,CC(=O)Cl.Cc1noc(C2CCN(C(=O)OC(C)(C)C)CC2)n1>>Cc1noc(C2CCNCC2)n1.Cl,,CO,,,,test
US05198451,CC=C(c1ccccc1)c1ccccc1.O=C1CCC(=O)N1Br>>BrCC=C(c1ccccc1)c1ccccc1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20050032871A1,Cc1[nH]c(C=O)c(CCC(=O)O)c1S(C)(=O)=O.O=C1Cc2cc(Br)ccc2N1>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(Br)cc32)c(CCC(=O)O)c1S(C)(=O)=O,,CCO,,C1CCNCC1,,test
US20090012063A1,CCCCCCc1cccc(-c2nc(I)c(C(=O)N3CCC(N(CC)CC)C3)n2C)c1>>CCCCCCc1cccc(-c2ncc(C(=O)N3CCC(N(CC)CC)C3)n2C)c1,[Pd],CO,,,,test
US05576324,Cc1cc2c3c(cc(C)c2[nH]c1=O)CC(CN=[N+]=[N-])O3.Cl>>Cc1cc2c3c(cc(C)c2[nH]c1=O)CC(CN)O3.Cl,[Pd],C1CCOC1,,[H][H],,test
US20090105227A1,C=Cc1ccccc1B(O)O.COC(=O)c1cc2[nH]c(Br)c(C3CCCCC3)c2s1>>C=Cc1ccccc1-c1[nH]c2cc(C(=O)OC)sc2c1C1CCCCC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US06479424B1,Cc1ccc(CCC(=O)O)cc1C.O=S(Cl)Cl>>Cc1ccc(CCC(=O)Cl)cc1C,,ClCCl,,,,test
US04168287,Brc1ccccc1.Clc1nc(Cl)nc(Cl)n1.c1ccccc1>>Clc1nc(-c2ccccc2)nc(-c2ccccc2)n1,,CCOCC,c1ccccc1,II,[Mg],test
US20120040954A1,COc1cc(O)cc(C=O)c1.O=C1OCCO1>>COc1cc(C=O)cc(OCCO)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080167356A1,CCOC(=O)c1cccc2cc(-c3ccc(OCc4c(CCc5c(Cl)cccc5Cl)noc4C(C)C)cc3)ccc12>>CC(C)c1onc(CCc2c(Cl)cccc2Cl)c1COc1ccc(-c2ccc3c(C(=O)O)cccc3c2)cc1,,C1CCOC1,,CCO,[Na+].[OH-],test
US06815465B1,C[C@H]1C[C@@H](C)C[C@H](C)[C@@H](O)C(C#N)=CC=CC[C@@H]([C@@H]2CCC[C@H]2C(=O)O)OC(=O)C[C@H](O)[C@@H](C)C1.NCc1cccnc1>>C[C@H]1C[C@@H](C)C[C@H](C)[C@@H](O)C(C#N)=CC=CC[C@@H]([C@@H]2CCC[C@H]2C(=O)O)OC(=O)C[C@H](O)[C@@H](C)C1.[NH-]Cc1cccnc1,,CO,ClC(Cl)Cl,,,test
US20100305096A1,CC1(C)CN(C(=O)OC(C)(C)C)CCN1.Cn1c(CBr)nc2c(N3CCOCC3)nc(Cl)nc21>>Cn1c(CN2CCN(C(=O)OC(C)(C)C)CC2(C)C)nc2c(N3CCOCC3)nc(Cl)nc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04554349,CC(=O)O[C@@H]1[C@@H](C)O[C@H](SCC=Cc2ccccc2)[C@@H](OC(C)=O)[C@H]1OC(C)=O>>C[C@H]1O[C@H](SCC=Cc2ccccc2)[C@@H](O)[C@@H](O)[C@@H]1O,,CO,,C[O-].[Na+],,test
US20100179126A1,Cc1ncc(CCCN(C)C)cc1Nc1ncc2c(n1)-c1ccc(C(F)(F)F)cc1NC(=S)C2.Cl>>Cc1ncc(CCCN(C)C)cc1Nc1ncc2c(n1)-c1ccc(C(F)(F)F)cc1NC(=S)C2.Cl,,CCO,,,,test
US20060270690A1,CN(C)C=CC(=O)c1cccc(N(C)S(C)(=O)=O)c1.N#Cc1cn[nH]c1N>>CN(c1cccc(-c2ccnc3c(C#N)cnn23)c1)S(C)(=O)=O,,CC(=O)O,,CCOC(C)=O,,test
US20060264415A1,NCCc1c[nH]c2ccccc12.O=C(COCc1ccc(F)cc1)NCCC1CCNCC1.O=C(n1ccnc1)n1ccnc1>>O=C(COCc1ccc(F)cc1)NCCC1CCN(C(=O)NCCc2c[nH]c3ccccc23)CC1,,C1CCOC1,,CCN(CC)CC,Cl,test
US20090042890A1,CCOC(=O)c1nc(Nc2ccc(O)cc2)nc(Nc2ccccc2OC)c1N.CCOC(=O)c1nc(Nc2ccc(O)cc2)nc(Nc2ccccc2OC)c1[N+](=O)[O-]>>COc1ccccc1-n1c(=O)[nH]c2c(C(N)=O)nc(Nc3ccc(O)cc3)nc21,[Pd],,,CCO,,test
US20090203763A1,CC(C)(C)OC(=O)N1CCC[C@@H]1CC(=O)O>>CN1CCC[C@@H]1CCO,,C1COCCO1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US05070089,C=O.CCCOC(=O)c1cc(O)c(O)c(O)c1.CSC(=S)N1CCNCC1>>CCCOC(=O)c1cc(O)c(O)c(O)c1CN1CCN(C(=S)SC)CC1,,CCO,,,,test
US04894386,CI.COC(=O)c1ccc(Cc2c[nH]c3ccc(C=O)cc23)c(OC)c1>>COC(=O)c1ccc(Cc2cn(C)c3ccc(C=O)cc23)c(OC)c1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20080293775A1,COc1cc(CC(=O)O)ccc1Cl>>O=C(O)Cc1ccc(Cl)c(O)c1,,CC(=O)O,,Br,,test
US20050090493A1,BrCC1CO1.Oc1ccc(Nc2nccc(Nc3ccccc3)n2)cc1>>c1ccc(Nc2ccnc(Nc3ccc(OCC4CO4)cc3)n2)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050043315A1,CC(C)n1nc(CC(=O)c2ccccc2)ccc1=O.CI.CS(C)=O.S=C=S>>CSC(SC)=C(C(=O)c1ccccc1)c1ccc(=O)n(C(C)C)n1,,ClC(Cl)Cl,O,[Na+].[OH-],,test
US20140135316A1,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.Cc1nnc2n1-c1ccc(Br)cc1N(c1ccc(Cl)cc1)CC2>>Cc1nnc2n1-c1ccc(-c3ccc(N)nc3)cc1N(c1ccc(Cl)cc1)CC2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080194618A1,CCBr.OC(c1ccccc1)(c1ccccc1)C12CCN(CC1)C2>>CC[N+]12CCC(C(O)(c3ccccc3)c3ccccc3)(CC1)C2.[Br-],,CC#N,,,,test
US20060009511A9,Cc1ccc(S(=O)(=O)OCC(F)(F)F)cc1.O=Cc1cccc(O)c1>>O=Cc1cccc(OCC(F)(F)F)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130345221A1,CCC(=O)Cl.Cc1sc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1CN>>CCC(=O)NCc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)sc1C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05204353,CN(C)c1nc(Cl)cc(Cl)n1.NCc1ccccc1F>>CN(C)c1nc(Cl)cc(NCc2ccccc2F)n1,,CCO,,CCN(CC)CC,,test
US20150252038A1,CC1(COc2cc(F)c(C(=O)OC(C)(C)C)cc2C2CC2)CN(C(=O)OC(C)(C)C)C1.CO.O=S(Cl)Cl>>COC(=O)c1cc(C2CC2)c(OCC2(C)CNC2)cc1F.Cl,,CO,,,,test
US20080188453A1,CC(=O)c1cc(C(=O)N2CC(O)C2)c(Nc2ccc(I)cc2F)n1C.CS(=O)(=O)Cl>>CC(=O)c1cc(C(=O)N2CC(OS(C)(=O)=O)C2)c(Nc2ccc(I)cc2F)n1C,,ClCCl,,CCN(CC)CC,,test
US20150065482A1,COc1ccc2c(c1)c(C(N)=O)nn2-c1cccc(I)c1>>NC(=O)c1nn(-c2cccc(I)c2)c2ccc(O)cc12,,ClCCl,,BrB(Br)Br,,test
US20080234261A1,CCNc1cc(Oc2cccc(NC(=O)OC(C)(C)C)c2)ncc1[N+](=O)[O-]>>CCNc1cc(Oc2cccc(NC(=O)OC(C)(C)C)c2)ncc1N,[Pd],CCO,,,,test
US20090062360A1,CCOC(=O)CN1C(=O)C(c2cccc(Cl)c2)=NC12CCCCC2>>O=C(O)CN1C(=O)C(c2cccc(Cl)c2)=NC12CCCCC2,,CO,O,[Na+].[OH-],,test
US20160213657A1,CCOc1cccc(-c2ccc(CC(NS(=O)(=O)c3ccccn3)c3cccc(NCC(=O)OC(=O)OC(C)(C)C)n3)cc2)c1>>CCOc1cccc(-c2ccc(CC(NS(=O)(=O)c3ccccn3)c3cccc(NCC(=O)O)n3)cc2)c1,,O,,C1COCCO1,Cl,test
US20090209524A1,CCCCCNc1nc(N)nc(C)c1CCCNCc1cccc(CC(=O)OC)c1.Cn1cnc(S(=O)(=O)Cl)c1>>CCCCCNc1nc(N)nc(C)c1CCCN(Cc1cccc(CC(=O)OC)c1)S(=O)(=O)c1cn(C)cn1,,ClCCl,,,,test
US04722934,CCOC(=S)NNC(=O)C(C)Oc1ccc(Oc2ccc(Cl)cc2)cc1>>CCOc1nnc(C(C)Oc2ccc(Oc3ccc(Cl)cc3)cc2)s1,,O=S(=O)(O)O,,,,test
US20130190307A1,BrBr.CC(=O)Nc1ccccc1C(C)=O>>CC(=O)Nc1ccc(Br)cc1C(C)=O,,CC(=O)O,,,,test
US05391541,CCOC(=O)C=C(N)C(F)(F)F.O=C=NCc1cc([N+](=O)[O-])cc(Cl)c1Cl>>O=c1cc(C(F)(F)F)[nH]c(=O)n1Cc1cc([N+](=O)[O-])cc(Cl)c1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20080045591A1,CI.COc1cc(/C=C/C(=O)CC(=O)c2ccc(O[Si](C)(C)C(C)(C)C)c(OC)c2)ccc1O[Si](C)(C)C(C)(C)C>>COc1cc(C=CC(=O)C(C)C(=O)c2ccc(O[Si](C)(C)C(C)(C)C)c(OC)c2)ccc1O[Si](C)(C)C(C)(C)C,,CCOCC,,[Na],,test
US20120046267A1,Nc1nccc2cc(-c3cccn4cncc34)oc12.O=C1CCC(=O)N1I>>Nc1ncc(I)c2cc(-c3cccn4cncc34)oc12,,CN(C)C=O,,,,test
US20040122014A1,Cl.N#CC(c1ccccc1)(c1ccccc1)[C@@H]1CCN(Cc2ccccc2)C1>>Cl.N#CC(c1ccccc1)(c1ccccc1)[C@@H]1CCN(Cc2ccccc2)C1,,CC(=O)OC(C)C,,,,test
US20110190490A1,CSc1nc(O)c(NC(=O)c2cccc(C)c2)c(O)n1>>CSc1nc(O)c2nc(-c3cccc(C)c3)oc2n1,,O=P(Cl)(Cl)Cl,,CCOCC,,test
US20150175623A1,CCOC(=O)[C@H](O)Cc1ccccc1OC.CCc1sc2ncnc(Cl)c2c1I>>CCOC(=O)[C@@H](Cc1ccccc1OC)Oc1ncnc2sc(CC)c(I)c12,,CS(C)=O,O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20090069340A1,Cc1ccc(Cl)cc1C1CCN(C(=O)OC(C)(C)C)CC1.Cn1c(CBr)c(Cl)c(=O)n1-c1ccccc1>>Cc1c(Cl)cccc1C1CCN(Cc2c(Cl)c(=O)n(-c3ccccc3)n2C)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20030233002A1,CCOC(=O)C1CCc2cc(NC(C)=O)ccc2O1>>CC(=O)Nc1ccc2c(c1)CCC(CO)O2,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120184559A1,CC(C)(C)OC(=O)NC(CNC[C@@H](COCc1ccccc1)NC(=O)OC(C)(C)C)COCc1ccccc1.CC=O>>CCN(CC(COCc1ccccc1)NC(=O)OC(C)(C)C)C[C@@H](COCc1ccccc1)NC(=O)OC(C)(C)C,,CC(Cl)Cl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20080027049A1,CC(C)(C)C(=O)Cl.Nc1ccc2oc3c(c2c1)CCCCC3>>CC(C)(C)C(=O)Nc1ccc2oc3c(c2c1)CCCCC3,,c1ccncc1,,,,test
US05134147,C=CCBr.COc1ccccc1O>>C=CCOc1ccccc1OC,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04962103,CC(=O)S[C@H]1C[C@@H](CO)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1.O=C=NC(=O)C(Cl)(Cl)Cl>>CC(=O)S[C@H]1C[C@@H](COC(=O)NC(=O)C(Cl)(Cl)Cl)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1,,CCOC(C)=O,,,,test
US04920120,CC(C)(C)OC(=O)NC1CCNC1.CCc1c(C(=O)O)c(=O)c2c(C)c(F)c(F)c(F)c2n1-c1ccc(F)cc1F>>Cc1c(F)c(N2CCC(N)C2)c(F)c2c1c(=O)c(C(=O)O)cn2-c1ccc(F)cc1F,,CC#N,,CCN(CC)CC,,test
US20110230464A1,COC(=O)CNCC(C)(C)NC(=O)OC(C)(C)C>>COC(=O)CNCC(C)(C)N,,ClCCl,O=C(O)C(F)(F)F,,,test
US20140296203A1,CCOC(=O)CCc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(NC(=O)NCc3ccccc3)ncc12>>CCOC(=O)CCc1n[nH]c2cc(NC(=O)NCc3ccccc3)ncc12,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20110201593A1,CC(C)(C)OC(=O)N1CC[C@@H](Nc2c([N+](=O)[O-])cnc3c2ccn3S(=O)(=O)c2ccccc2)[C@H](F)C1>>CC(C)(C)OC(=O)N1CC[C@@H](Nc2c(N)cnc3c2ccn3S(=O)(=O)c2ccccc2)[C@H](F)C1,[Pd],CCOC(C)=O,,,,test
US20030069294A1,COCCl.Cc1cc(OC(=O)C(C)(C)C)c(C)c(C)c1O>>COCOc1c(C)cc(O)c(C)c1C,,C1CCOC1,,[H-].[Na+],,test
US20110245386A1,C=C(C)C.CCCCP(O)O>>CCCCP(=O)(O)CC(C)C,,CC(=O)O,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20110306722A1,COC(=O)[C@H](CCCCNC(=O)c1ccc(NC(=O)OCc2ccccc2)cc1)n1c2ccccc2c2ccccc21>>COC(=O)C(CCCCNC(=O)c1ccc(N)cc1)n1c2ccccc2c2ccccc21,[Pd],CC(C)O,,C1CCOC1,,test
US20050148604A1,N#CCC#N.O=C(Cl)C1CCCCC1>>N#CC(C#N)=C(O)C1CCCCC1,,C1CCOC1,,Cl,[H-].[Na+],test
US20070225335A1,COC(=O)c1cc(-c2ccncc2)n(-c2cccc(F)c2)n1>>O=C(O)c1cc(-c2ccncc2)n(-c2cccc(F)c2)n1,,C1COCCO1,O,Cl,[Na+].[OH-],test
US20060035978A1,CCC(=NC#N)NC(C)c1ccc(Cl)cc1Cl.CI>>CCC(=NC#N)N(C)C(C)c1ccc(Cl)cc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US05250700,BrCCCc1cccnc1.COc1ccc(C2CC(=O)NN2C)cc1OC1CCCC1>>COc1ccc(C2CC(=O)N(CCCc3cccnc3)N2C)cc1OC1CCCC1,,CN(C)C=O,,[H-].[Na+],,test
US20110230458A1,CC(C)(C)OC(=O)N1CC[C@H](CN=[N+]=[N-])[C@H](O)C1>>[N-]=[N+]=NC[C@H]1CCNC[C@H]1O,,Cl,ClCCl,,,test
US20090176804A1,CO.O=C(Cl)C(=O)Cl.O=S(=O)(NC1CCCCC1)c1cc(-c2cc3ccccc3[nH]2)ccc1Cl>>COC(=O)C(=O)c1c(-c2ccc(Cl)c(S(=O)(=O)NC3CCCCC3)c2)[nH]c2ccccc12,,ClCCl,,,,test
US20020077338A1,COc1cccc(C)c1OC.ClCCOCCCl>>COc1ccc(Cl)c(C)c1OC,,CC(=O)O,O,,,test
US20100048567A1,CCOC(=O)c1cnc(Cl)nc1Nc1ccc(-c2cscn2)c(F)c1>>O=C(O)c1cnc(Cl)nc1Nc1ccc(-c2cscn2)c(F)c1,,C1CCOC1,,[Li+].[OH-],,test
US20050197350A1,CNc1ccnc(N[C@H]2CC[C@@H](NC(=O)OC(C)(C)C)CC2)n1>>CNc1ccnc(N[C@@H]2CC[C@H](N)CC2)n1,,CCOC(C)=O,,Cl,,test
US20110245205A1,CC(O)(CO[Si](C)(C)C(C)(C)C)c1nccs1.O=C1CCC(=O)N1Br>>CC(O)(CO[Si](C)(C)C(C)(C)C)c1ncc(Br)s1,,CN(C)C=O,,O,,test
US20160200666A1,C#Cc1cccc(N)c1.CC1C(=O)CCCC1=O>>C#Cc1cccc(NC2=C(C)C(=O)CCC2)c1,,CO,,CC(=O)O,,test
US20020169165A1,CNC.Cc1cc(Nc2ncnc3ccc(C#CCNC(=O)CCl)cc23)ccc1Oc1cccnc1>>Cc1cc(Nc2ncnc3ccc(C#CCNC(=O)CN(C)C)cc23)ccc1Oc1cccnc1,,CO,,C1CCOC1,,test
US20100298336A1,BrP(Br)Br.CCc1ncccc1CO>>CCc1ncccc1CBr,,ClCCl,,,,test
US20130172292A1,COCCn1c(S(C)(=O)=O)nc2cccnc21.Oc1ccc(-c2nn(CC(F)F)c3cc(F)cnc23)cc1>>COCCn1c(Oc2ccc(-c3nn(CC(F)F)c4cc(F)cnc34)cc2)nc2cccnc21,,CN(C)C=O,,O,[H-].[Na+],test
US20150148340A1,CCOC(=O)c1cn(-c2ccc3ncn(C)c3c2)c(=O)[nH]c1=O.FC(F)(F)c1cccc(CBr)c1Cl>>CCOC(=O)c1cn(-c2ccc3ncn(C)c3c2)c(=O)n(Cc2cccc(C(F)(F)F)c2Cl)c1=O,,CO,ClCCl,,,test
US20110105566A1,CC(C)(C)OC(=O)Nc1cccc(C=O)n1>>CC(C)(C)OC(=O)Nc1cccc(CO)n1,,C1CCOC1,,[BH4-].[Na+],,test
US20160046597A1,Cn1cc(C2CCN(C(=O)[O-])CC2)c2cc(NC(=O)c3cccc(C#N)c3)cnc21>>Cn1cc(C2CCNCC2)c2cc(NC(=O)c3cccc(C#N)c3)cnc21,,C1COCCO1,,Cl,,test
US20150322056A1,Fc1cncc(F)c1F.Ic1cc[nH]n1>>Fc1cncc(F)c1-n1ccc(I)n1,,CS(C)=O,,[H-].[Na+],,test
US20150210708A1,COC(=O)C12CCC(NC(=O)OC(C)(C)C)(CC1)C2>>CC(C)(C)OC(=O)NC12CCC(C(=O)O)(CC1)C2,,C1CCOC1,CO,[Na+].[OH-],,test
US20110144105A1,CCOC(=O)C(C)(C)Oc1cnc2c(c1)cc(C(=CC1CCCC1)c1ccc(S(C)(=O)=O)cc1)n2S(=O)(=O)c1ccccc1>>CCOC(=O)C(C)(C)Oc1cnc2[nH]c(C(=CC3CCCC3)c3ccc(S(C)(=O)=O)cc3)cc2c1,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040157886A1,COc1ccc(CC2CCN(C(=O)C(=O)Nc3ccc4[nH]c(=O)oc4c3)CC2)cc1>>O=C(Nc1ccc2[nH]c(=O)oc2c1)C(=O)N1CCC(Cc2ccc(O)cc2)CC1,,CCOCC,,,,test
US20090036434A1,CNCC1CCN(C(=O)OC(C)(C)C)CC1.Clc1cc(Cl)ncn1>>CN(CC1CCN(C(=O)OC(C)(C)C)CC1)c1cc(Cl)ncn1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20050075293A1,COC(=O)C(Cc1ccc(Oc2ccc(CC3SC(=O)NC3=O)cc2)cc1)NC(=O)CNC(=O)OC(C)(C)C.Cl>>COC(=O)C(Cc1ccc(Oc2ccc(CC3SC(=O)NC3=O)cc2)cc1)NC(=O)CN.Cl,,ClCCl,,,,test
US20070021443A1,O=c1[nH]c2cnc(-n3cnc4ccccc43)nc2n1C1CCCc2c1ccn2S(=O)(=O)c1ccccc1>>O=c1[nH]c2cnc(-n3cnc4ccccc43)nc2n1C1CCCc2[nH]ccc21,,CO,,[Na+].[OH-],,test
US20060211739A1,CN(C)Cc1ccsc1CNC(=S)c1cccc(C(F)(F)F)c1Cl.C[Si](C)(C)N=[N+]=[N-]>>CN(C)Cc1ccsc1Cn1nnnc1-c1cccc(C(F)(F)F)c1Cl,,C1CCOC1,,,,test
US06255496B1,COC(=O)CCc1ccc(OCCSCCOC(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1>>O=C(O)CCc1ccc(OCCSCCOC(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1,,O,,CCO,[K+].[OH-],test
US04010177,C=O.c1ccc(C2=NCc3nncn3-c3ccccc32)cc1>>O=C(c1ccccc1)c1ccccc1,,O=CO,,,,test
US20040082542A1,CCCCN.O=[N+]([O-])c1ccc(F)cc1F>>CCCCNc1cc(F)ccc1[N+](=O)[O-],,CN(C)C=O,,CCN(CC)CC,,test
US20070185111A1,Clc1nnc(Cl)c2ccccc12.OC1CCCNC1>>OC1CCCN(c2nnc(Cl)c3ccccc23)C1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05741781,COC(=O)[C@@H]1CCC(c2cccc(O)c2)N1.O=C(O)CNC(=O)OCc1ccccc1>>COC(=O)[C@@H]1CCC(c2cccc(O)c2)N1C(=O)CNC(=O)OCc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20060293340A1,Cc1ccc(N)cc1Nc1nccc(-c2cnccn2)n1.O=C(O)c1cc(F)cc(C(F)(F)F)c1>>Cc1ccc(NC(=O)c2cc(F)cc(C(F)(F)F)c2)cc1Nc1nccc(-c2cnccn2)n1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20110003793A1,Cl.Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CNCCC2>>Cl.Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CNCCC2,,ClCCl,,CCOCC,,test
US20130188270A1,CCCCC(CC)Cn1c2ccccc2c2cc(C(=O)c3ccc(F)cc3)c3ccccc3c21.Cc1cc(C)c(C(=O)Cl)c(C)c1>>CCCCC(CC)Cn1c2ccc(C(=O)c3c(C)cc(C)cc3C)cc2c2cc(C(=O)c3ccc(F)cc3)c3ccccc3c21,,Clc1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US04332808,CCCI.Cn1ccc2c(C3(O)CCCNC3)cccc21>>CCCN1CCCC(O)(c2cccc3c2ccn3C)C1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20090291992A1,CC1(CN2C(=O)SC(=Cc3ccc(O)c(C(F)(F)F)c3)C2=O)CCCCC1>>CC1(CN2C(=O)SC(Cc3ccc(O)c(C(F)(F)F)c3)C2=O)CCCCC1,[Pd],CO,,,,test
US20070293472A1,CCOC(=O)c1cn(CC)c2ccc(C#CCNC(=O)OC(C)(C)C)cc2c1=O>>CCOC(=O)c1cn(CC)c2ccc(CCCNC(=O)OC(C)(C)C)cc2c1=O,[Pd],ClCCl,,,,test
US04347254,CCOC(=O)C1(C(=O)OCC)CC2C=CC1C2>>OCC1(CO)CC2C=CC1C2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06344483B1,CC(=O)NC(CC#CCN)C(=O)O.CCOC(=N)CF.Cl>>CC(=O)NC(CC#CCNC(=N)CF)C(=O)O.Cl,,CCO,,C1CCC2=NCCCN2CC1,,test
US20070082912A1,CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(S(C)(=O)=O)ccc2OCc2ccc(F)cc2)c1>>Cc1ccc(-c2cc(S(C)(=O)=O)ccc2OCc2ccc(F)cc2)n1-c1cccc(C(=O)O)c1,,CCOC(C)=O,,CCO,,test
US05773428,COC(=O)C(C(=O)OCc1ccccc1)[C@@H](CC(C)C)C(=O)N[C@H]1Cc2cn(c3ccccc23)CCCCCCNC1=O>>COC(=O)C(C(=O)O)[C@@H](CC(C)C)C(=O)N[C@H]1Cc2cn(c3ccccc23)CCCCCCNC1=O,[Pd],CCO,,O=C[O-].[NH4+],,test
US06884868B1,CCOC(=O)c1ccc(F)cc1.C[C@H]1CN(c2ccc(N3CCNCC3)cc2)C[C@@H](C)O1>>CCOC(=O)c1ccc(N2CCN(c3ccc(N4C[C@H](C)O[C@H](C)C4)cc3)CC2)cc1,,CS(C)=O,ClCCl,O,O=C([O-])[O-].[K+].[K+],test
US20050288515A1,CCS(=O)(=O)c1ccc(C)c(Nc2ncc(-c3cccc(O)c3)o2)c1.OCC1CC1>>CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(-c3cccc(OCC4CC4)c3)o2)c1,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090137557A1,CCCC[Sn](CCCC)(CCCC)c1ccco1.COc1ccccc1-c1nc(C)c(Cl)c(=O)n1CCc1ccccc1>>COc1ccccc1-c1nc(C)c(-c2ccco2)c(=O)n1CCc1ccccc1,,C1COCCO1,,[Cs+].[F-],,test
US20140249159A1,CC(C)(C)[Si](C)(C)OCc1nnc(C(=O)c2cnc(Cl)c(Cl)c2)o1>>CC(C)(C)[Si](C)(C)OCc1nnc(C(O)c2cnc(Cl)c(Cl)c2)o1,,C1CCOC1,CCO,CC(=O)O,[BH4-].[Na+],test
US20140356322A1,N#Cc1ccc(C=O)cc1.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>N#Cc1ccc(-c2cnco2)cc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20090247590A1,CC(=O)Cl.CCOC(=O)c1ccc2c(c1)CCC2NCCc1c[nH]c2ccccc12>>CCOC(=O)c1ccc2c(c1)CCC2N(CCc1c[nH]c2ccccc12)C(C)=O,,ClCCl,,CCN(CC)CC,Cl,test
US20060281771A1,COc1cc2ncnc(N3CCC(NC(=O)OC(C)(C)C)CC3)c2cc1OC.O=C(O)C(F)(F)F>>COc1cc2ncnc(N3CCC(N)CC3)c2cc1OC.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20050080124A1,COc1ccc([N+](=O)[O-])cc1-c1c(Br)c(C(F)(F)F)nn1C>>COc1ccc(N)cc1-c1c(Br)c(C(F)(F)F)nn1C,,CCO,,,,test
US04481142,Clc1ccc2c(c1)C(c1ccccc1Cl)NCc1cncnc1-2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(N1Cc2cncnc2-c2ccc(Cl)cc2C1c1ccccc1Cl)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US06358971B1,CC(C)Cc1c(NC(=O)C(F)(F)F)nc2ccc(C(=O)c3ccccc3)cn12>>CC(C)Cc1c(N)nc2ccc(C(=O)c3ccccc3)cn12,,CCOC(C)=O,,,,test
US20140275087A1,Cn1cnc(S(=O)(=O)Cl)c1.c1ccc(CC2CNCC2c2ccccc2)cc1>>Cn1cnc(S(=O)(=O)N2C[C@@H](c3ccccc3)[C@H](Cc3ccccc3)C2)c1,,ClCCl,,CCN(CC)CC,Cl,test
US20160272632A1,CCOC(C)=O.CN(C)C=O.N#CC[C@@]1(n2nc(Nc3ccc(Cl)cc3)c3c(=O)[nH]ccc32)CC[C@@H](C(=O)O)OC1>>CON(C)C(=O)[C@@H]1CC[C@@](CC#N)(n2nc(Nc3ccc(Cl)cc3)c3c(=O)[nH]ccc32)CO1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080194561A1,NCC(=O)O.O=C=Nc1cccc([N+](=O)[O-])c1>>O=C(O)CNC(=O)Nc1cccc([N+](=O)[O-])c1,,O,,[K+].[OH-],,test
US20080015199A1,COc1ccc(F)c(CCCO)c1O>>COc1ccc(F)c2c1OCCC2,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140121200A1,CN(CCO)c1ccc(-c2cc3nccnc3c(NCC3CN(C(=O)OC(C)(C)C)CCC3(F)F)n2)cc1>>CN(CCO)c1ccc(-c2cc3nccnc3c(NCC3CNCCC3(F)F)n2)cc1,,CCOC(C)=O,,Cl,,test
US20020068752A1,CCOC(=O)c1c(C)[nH]c2cc(Br)c(CC(=O)O)cc12.COc1cccc(CCN)c1>>CCOC(=O)c1c(C)[nH]c2cc(Br)c(CC(=O)NCCc3cccc(C)c3)cc12,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US05180728,Cc1c(CCl)ncn1C(c1ccccc1)(c1ccccc1)c1ccccc1.Cc1c2n(c3ccccc13)C(=O)NCC2>>Cc1c2n(c3ccccc13)C(=O)N(Cc1ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c1C)CC2,,CN(C)C=O,O,[H-].[Na+],,test
US04550103,CC(C)(C)OC(=O)NC1CCN(Cc2ccccc2)C1>>CC(C)(C)OC(=O)NC1CCNC1,[Pd],C1CCOC1,,[H][H],,test
US20090275628A1,CCOC(=O)C1=NOC2(CCC(C(C)(C)C)CC2)C1>>CC(C)(C)C1CCC2(CC1)CC(C(=O)O)=NO2,,CO,O,[Li+].[OH-],,test
US20130289027A1,C=CCC(C(=O)O)c1c(-c2ccc(C)cc2C)c2ccccc2c(=O)n1C>>CCCC(C(=O)O)c1c(-c2ccc(C)cc2C)c2ccccc2c(=O)n1C,O=[Pt]=O,CCOC(C)=O,,,,test
US20080058528A1,CN(C)c1ccncc1.CN1CCCC1=O.O=C(O)c1ccnc(Cl)c1>>CC(C)(C)OC(=O)c1ccnc(Cl)c1,CN(C)c1ccncc1,CN1CCCC1=O,,,,test
US06187777B1,C1CCNCC1.CCCCc1cc2nc(C)cc(Cl)c2o1>>CCCCc1cc2nc(C)cc(N3CCCCC3)c2o1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20120142717A1,N#CN.OCCc1ccc(Oc2cc(Cl)cc(C(F)(F)F)c2)cc1>>N=C(N)OCCc1ccc(Oc2cc(Cl)cc(C(F)(F)F)c2)cc1,,C1CCOC1,,O=S(=O)(O)C(F)(F)F,,test
US05922718,Fc1cccc(F)c1.O=C(Cl)CCCl>>O=C(CCCl)c1ccc(F)cc1F,,O,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20070203245A1,Cc1ccc(CNC(=O)C2CCC(CNC(=O)OC(C)(C)C)CC2)cc1>>Cc1ccc(CNC(=O)C2CCC(CN)CC2)cc1,,CO,ClCCl,O=C(O)C(F)(F)F,,test
US20140135318A1,CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1CN=[N+]=[N-]>>[N-]=[N+]=NC[C@@H]1Cc2ccccc2CN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05061706,CCOC(=O)C(=O)Nc1cc(OC)ccc1[N+](=O)[O-]>>COc1ccc2c(c1)[nH]c(=O)c(=O)n2O,[Pt],CN(C)C=O,,,,test
US20140005146A1,COC(=O)[C@@H](N)c1ccccc1.NC(=O)c1cnn2cc(Br)cc2c1Cl>>COC(=O)[C@@H](Nc1c(C(N)=O)cnn2cc(Br)cc12)c1ccccc1,,CCOC(C)=O,CN1CCCC1=O,CCN(C(C)C)C(C)C,Cl,test
US20140350019A1,CCOC(=O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)cc(C)c2OC)c1F>>COc1c(C)cc(-c2cccc(F)c2)cc1CNc1c(F)ccc(OCC(=O)O)c1F,,C1CCOC1,,O,[Li+].[OH-],test
US20120142707A1,C=C(C)[C@@H]1CC[C@]2(C(=O)OC)CC[C@]3(C)[C@H](CCC4[C@@]5(C)CC=C(OS(=O)(=O)C(F)(F)F)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.O=C(O)c1cccc(B(O)O)c1>>C=C(C)[C@@H]1CC[C@]2(C(=O)OC)CC[C@]3(C)[C@H](CCC4[C@@]5(C)CC=C(c6cccc(C(=O)O)c6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20020035276A1,CCCCOC(=O)C1CCc2cc(C(C)(C)C)cc(C(C)(C)C)c2O1>>CC(C)(C)c1cc2c(c(C(C)(C)C)c1)OC(C(=O)O)CC2,,Cc1ccccc1,,CO,[Na+].[OH-],test
US20130310361A1,CC(C)c1noc(CCCl)n1.Cc1cc(Nc2nc(Nc3cc(C)c(C4CCNCC4)cc3C)ncc2Cl)n[nH]1>>Cc1cc(Nc2nc(Nc3cc(C)c(C4CCN(CCc5nc(C(C)C)no5)CC4)cc3C)ncc2Cl)n[nH]1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US20150210800A1,COC(=O)c1sc2c(c1Br)CSC2>>O=C(O)c1sc2c(c1Br)CSC2,,C1CCOC1,,O,[Li+].[OH-],test
US20090264498A1,CC(C)(C)OC(=O)N1CC[C@@H](NS(=O)(=O)c2cc(Br)ccc2Br)C1.CCCBr>>CCCN([C@@H]1CCN(C(=O)OC(C)(C)C)C1)S(=O)(=O)c1cc(Br)ccc1Br,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20110230463A1,O=CC1=Cc2ccc(O)cc2OC1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=CC1=Cc2ccc(OS(=O)(=O)C(F)(F)F)cc2OC1,,ClCCl,,O,c1ccncc1,test
US04302607,COP(=O)(CC(=O)CP(=O)(OC)OC)OC.O=CCCCCCCCCCCC=O>>COP(=O)(CC(=O)C=CCCCCCCCCCCC=O)OC,,CC(C)(C)O,O,O=C([O-])O.[K+],,test
US20070218010A1,CC(=O)[C@@]1(O)[C@@](O)(C(C)=O)[C@](O)(C(C)=O)[C@@](O)(Oc2ccc(C(O)c3ccccn3)cc2)O[C@@]1(CO)C(C)=O.O=S(Cl)Cl>>CC(=O)[C@@]1(O)[C@@](O)(C(C)=O)[C@](O)(C(C)=O)[C@@](O)(Oc2ccc(C(Cl)c3ccccn3)cc2)O[C@@]1(CO)C(C)=O,,ClCCl,,,,test
US20040023973A1,N#Cc1ccccc1-c1cc(-c2ccccn2)cn(CC2CCNCC2)c1=O.O=Cc1ccccc1>>N#Cc1ccccc1-c1cc(-c2ccccn2)cn(CC2CCN(Cc3ccccc3)CC2)c1=O,,ClC(Cl)Cl,,CC(=O)O,,test
US20120122931A1,CCOC(=O)c1cccc(C(O)c2c(-c3cccnc3)[nH]c3cc(Cl)ccc23)n1>>CCOC(=O)c1cccc(Cc2c(-c3cccnc3)[nH]c3cc(Cl)ccc23)n1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20040127426A1,COC(=O)c1cscc1S(N)(=O)=O>>O=C1NS(=O)(=O)c2ccsc21,,CO,,Cl,C[O-].[Na+],test
US20070066820A1,COc1ccc(CCl)cc1.c1ccc(-c2cc[nH]n2)cc1>>COc1ccc(Cn2ccc(-c3ccccc3)n2)cc1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110251190A1,CN(C)c1cc2c(=O)c3cc(-c4cccnc4F)ccc3oc2cn1.C[Mg]Cl>>CN(C)c1cc2c(cn1)Oc1ccc(-c3cccnc3F)cc1C2(C)O,,C1CCOC1,,,,test
US20100063058A1,O=P(Br)(Br)Br.Oc1nnc(C(F)(F)F)cc1Br>>FC(F)(F)c1cc(Br)c(Br)nn1,,ClCCl,,O,O=C([O-])O.[Na+],test
US20150307454A1,COC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2ncc3ccccc3c2C2CC2)c(C)c1>>Cc1cc(C(=O)O)ccc1S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1,,CCO,,[Na+].[OH-],,test
US04062869,CC(C)COC(=O)C(=O)c1c[nH]c2ccccc12>>OCCc1c[nH]c2ccccc12,,CC(C)O,O,[BH4-].[Na+],,test
US08946413B2,COC(=O)[C@@]1(CC(F)F)C=C[C@@H](n2c(C)ccc2C)C1>>Cc1ccc(C)n1C1C=CC(CC(F)F)(C(=O)O)C1,,CO,,[Na+].[OH-],,test
US20130190312A1,COCCCl.Nc1ccc(Br)cn1>>COCCNc1ccc(Br)cn1,,CN(C)C=O,,[H][H],[H-].[Na+],test
US20150284386A1,CN1C(=O)C(C)(C)c2ccc(NCc3ccccc3)nc21.Cl>>CN1C(=O)C(C)(C)c2ccc(N)nc21.Cl,[Pd],CCO,,,,test
US20080234255A1,CCOC(=O)CCN(c1nc(Cl)ncc1[N+](=O)[O-])C1CCC(C)C1>>CCOC(=O)CCN(c1nc(Cl)ncc1N)C1CCC(C)C1,[Pd],CCOC(C)=O,,[H][H],,test
US20030229094A1,C=O.NC(=O)c1cccc(C(F)(F)F)c1.c1ccc(N2CCNCC2)nc1>>O=C(NCN1CCN(c2ccccn2)CC1)c1cccc(C(F)(F)F)c1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20090269301A1,CCCCCCC(=O)C(=O)OCC.NCCCn1ccnc1.O=Cc1cccc(Cl)c1>>CCCCCC1=C(O)C(=O)N(CCCn2ccnc2)C1c1cccc(Cl)c1,,CCO,,,,test
US20150259359A1,COc1ccc(C=O)c(OC)c1.C[C@@H]1CN[C@@H](CO)CN1C(=O)OC(C)(C)C>>COc1ccc(CN2C[C@@H](C)N(C(=O)OC(C)(C)C)C[C@@H]2CO)c(OC)c1,,ClCCCl,,O=C([O-])O.[Na+],,test
US20040122001A1,N#Cc1ccc2ccsc2c1.O=C1CCC(=O)N1Br>>N#Cc1ccc2c(Br)csc2c1,,CN(C)C=O,O,,,test
US20150336953A1,C#CCNc1cc(Cl)nc(SC)n1.O=C1CCC(=O)N1Br>>C#CCNc1nc(SC)nc(Cl)c1Br,,ClCCl,,,,test
US04442126,CCCN(CCC)C1CCc2cc(OC)c([N+](=O)[O-])cc2C1>>CCCN(CCC)C1CCc2cc(OC)c(N)cc2C1,[Ni],CCO,,,,test
US20110105532A1,O=C(/C=C/c1cccc([N+](=O)[O-])c1)NC(c1cccc(C(F)(F)F)c1)C(F)(F)F>>Nc1cccc(/C=C/C(=O)NC(c2cccc(C(F)(F)F)c2)C(F)(F)F)c1,,CCO,,O,[Na+].[OH-],test
US20100234365A1,COc1ccc(CN(Cc2ccc(OC)cc2)S(=O)(=O)CCN2C[C@H](c3cccc(OCCOC4CCCCO4)c3)N(c3ccc(Oc4ccc(Cl)cc4)cc3)C2=O)cc1>>NS(=O)(=O)CCN1C[C@H](c2cccc(OCCO)c2)N(c2ccc(Oc3ccc(Cl)cc3)cc2)C1=O,,O=C(O)C(F)(F)F,,O,[Na+].[OH-],test
US20160128326A1,C#CCBr.CCc1cc(C)cc(CC)c1C1=C(OC)CCC1=O>>C#CCC1CC(=O)C(c2c(CC)cc(C)cc2CC)C1=O,,C1CCOC1,Cc1ccccc1,CC(C)[N-]C(C)C.[Li+],,test
US20110039855A1,CC(C)(C)OC(=O)N1CC[C@H](O)[C@H]1COS(C)(=O)=O.CC(C)OC(=O)N[C@@H]1Cc2[nH]c3ccc(C#N)cc3c2C1>>CC(C)OC(=O)N[C@H]1Cc2c(n(C[C@@H]3[C@@H](O)CCN3C(=O)OC(C)(C)C)c3ccc(C#N)cc23)C1,,CCOC(C)=O,CN(C)C=O,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US04350706,CC(Oc1ccc(N=C=O)cc1)c1ccccc1.[NH-]C(=O)c1ccccc1Br>>CC(Oc1ccc(NC(=O)NC(=O)c2ccccc2Br)cc1)c1ccccc1,,CC#N,,[H-].[Na+],,test
US20120190635A1,C#CCCCCCCCCCO.CC(=O)OC1C(F)OC(C)CC1N(C)C>>C#CCCCCCCCCCOC1OC(C)CC(N(C)C)C1OC(C)=O,,CCOC(C)=O,,CCOCC,FB(F)F,test
US20110118251A1,NO.O=Cc1cccnc1Br>>ON=Cc1cccnc1Br,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20090270405A1,Cc1cc(N)nc(C)c1C#N.O=c1ccccn1C(=S)n1ccccc1=O>>Cc1cc(N=C=S)nc(C)c1C#N,,ClCCl,,,,test
US20110028450A1,C#CCBr.CC(C)(C)OC(=O)NCCO[Si](C)(C)C(C)(C)C>>C#CCN(CCO[Si](C)(C)C(C)(C)C)C(=O)OC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US04377695,COC(=O)CCCCCCCBr.O=c1[nH]c2ccccc2n1-c1cccc(Cl)c1>>COC(=O)CCCCCCCn1c(=O)n(-c2cccc(Cl)c2)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US05053422,CC(C)COC(=O)CCC1NCC(=O)N1>>O=C1CN2C(=O)CCC2N1,,O,,Cl,O=C([O-])O.[Na+],test
US06486328B1,C=CC1(O[Si](C)(C)C)C=CC=CC1.O=C1N(Cc2ccccc2)C(O)[C@@H]2CS[C@@H](c3ccccc3)N12>>O=C(C[C@H]1[C@@H]2CS[C@@H](c3ccccc3)N2C(=O)N1Cc1ccccc1)c1ccccc1,,CCOCC,ClCCl,FB(F)F,,test
US20100130489A1,COc1ccc(N)cc1.O=[N+]([O-])c1c(Cl)nc2cc(C(F)(F)F)ccc2c1Cl>>COc1ccc(Nc2c([N+](=O)[O-])c(Cl)nc3cc(C(F)(F)F)ccc23)cc1,,CN(C)C=O,Cl,CCN(CC)CC,,test
US20160016948A1,CC(C)n1cc(I)c2cnc(Cl)cc21.O=C=O>>CC(C)n1cc(C(=O)O)c2cnc(Cl)cc21,,C1CCOC1,,[Li]CCCC,,test
US06297196B1,Cc1cc(C(=O)O)c(C)c2c1S(=O)(=O)CCC2Oc1ncc(C(F)(F)F)cc1Cl.O=C1CCCCC1=O>>Cc1cc(C(=O)OC2=CC(=O)CCC2)c(C)c2c1S(=O)(=O)CCC2Oc1ncc(C(F)(F)F)cc1Cl,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20080275097A1,CC(C)(C)OC(=O)n1nc(CBr)c2cccnc21.N#Cc1cc(Cl)cc(Oc2c(Cl)ccc3[nH]nnc23)c1>>CC(C)(C)OC(=O)n1nc(Cn2nnc3c(Oc4cc(Cl)cc(C#N)c4)c(Cl)ccc32)c2cccnc21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150152069A1,CC(=O)N1CCN(c2ccc([N+](=O)[O-])c(Nc3ccccc3)c2)CC1>>CC(=O)N1CCN(c2ccc(N)c(Nc3ccccc3)c2)CC1,[Pd],CCO,,,,test
US04044015,CI.COc1ccc(-c2cn3ccccc3n2)cc1>>COc1ccc(-c2cn3ccccc3[n+]2C)cc1.[I-],,CC#N,,,,test
US20060257987A1,CCCC(CCO)Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1.CS(=O)(=O)Cl>>CCCC(CCOS(C)(=O)=O)Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1,,ClCCl,,O,,test
US20030199456A1,O=C1c2ccccc2C(=O)N1CCC#Cc1ccc(OCCO)cc1>>O=C1c2ccccc2C(=O)N1CCCCc1ccc(OCCO)cc1,[Pd],CCOC(C)=O,CO,[H][H],,test
US20060223890A1,CN1CCNCC1.O=C(O)c1cn(S(=O)(=O)c2ccccc2)c2ccccc12>>CN1CCN(C(=O)c2cn(S(=O)(=O)c3ccccc3)c3ccccc23)CC1,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20110046121A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.O=[N+]([O-])c1ccc2[nH]nc(Br)c2c1>>CC(C)(C)OC(=O)N1CC=C(c2n[nH]c3ccc([N+](=O)[O-])cc23)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20090306102A1,Cc1cccc(C(=O)Cl)n1.NC(=O)c1ccccc1N>>Cc1cccc(C(=O)Nc2ccccc2C(N)=O)n1,,CN(C)C=O,ClCCl,CCN(CC)CC,,test
US20130225620A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.Cn1ncc2c(Br)cc(F)cc21>>C=C(OCC)c1cc(F)cc2c1cnn2C,,CN1CCCC1=O,,,,test
US05789415,CCOC(=O)Cc1ccc2cc(CBr)ccc2c1.CCc1nc2nc(C)cc(C)c2[nH]1>>CCOC(=O)Cc1ccc2cc(Cn3c(CC)nc4c(C)cc(C)nc43)ccc2c1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20050009109A1,CC(O)(C(=O)c1ccc(F)cc1)C(F)(F)F.CCNCC>>CCN(CC)c1ccc(C(=O)C(C)(O)C(F)(F)F)cc1,Cc1ccc(S(=O)(=O)O)cc1,CS(C)=O,,,,test
US20120184565A1,COc1ccc(CBr)cc1.O=[N+]([O-])c1ccc(Cl)c(O)c1>>COc1ccc(COc2cc([N+](=O)[O-])ccc2Cl)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20160257653A1,CC(C)(C)OC(=O)NCC/C=C/c1cccc([N+](=O)[O-])c1>>CC(C)(C)OC(=O)NCCCCc1cccc(N)c1,[Pd],CO,,,,test
US20100261755A1,CC1(C)OB(c2ccc(Cl)c(F)c2)OC1(C)C.COC(=O)c1ccnc(Cl)c1>>COC(=O)c1ccnc(-c2ccc(Cl)c(F)c2)c1,Cl[Pd]Cl,CO,O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US04837236,CC(=Cc1cccc(Oc2ccccc2)c1)CBr.CC1CNCC(C)O1>>CC(=Cc1cccc(Oc2ccccc2)c1)CN1CC(C)OC(C)C1,,[Na+],[OH-],,,test
US05958924,COc1ccc2[nH]c(=O)cc(CCCl)c2c1.O=C(c1ccc(F)cc1)C1CCNCC1>>COc1ccc2[nH]c(=O)cc(CCN3CCC(C(=O)c4ccc(F)cc4)CC3)c2c1.Cl,,CC#N,,O=C([O-])O.[Na+],,test
US20050075334A1,CS(=O)(=O)c1nc2cc(Cl)c(F)cc2[nH]1.O=C(O)c1cc(S)c2[nH]c(=O)[nH]c2c1>>O=C(O)c1cc(Sc2nc3cc(Cl)c(F)cc3[nH]2)c2[nH]c(=O)[nH]c2c1,,C1CCOC1,CC(C)O,,,test
US20030114472A1,Cc1cc(C#N)cc(C)c1Oc1nc(Nc2ccc(C#N)cc2)nc(Cl)c1Br.N>>Cc1cc(C#N)cc(C)c1Oc1nc(Nc2ccc(C#N)cc2)nc(N)c1Br,,O,,C1COCCO1,,test
US20090142297A1,NCc1ccc2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C=Nc1ccccc1>>O=C1CCC(N2C(=O)c3ccc(CNC(=O)Nc4ccccc4)cc3C2=O)C(=O)N1,,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US20120302610A1,CCOC(=O)CCNC(=O)c1ccc(-c2cc(F)c(F)cc2C(=O)Nc2ccc(-c3ccc(Cl)cc3Cl)cc2)cn1>>O=C(O)CCNC(=O)c1ccc(-c2cc(F)c(F)cc2C(=O)Nc2ccc(-c3ccc(Cl)cc3Cl)cc2)cn1,,C1CCOC1,,[Na+].[OH-],,test
US20160184318A1,C=CC(=O)Cl.Cc1nc(CN2CCNCC2)co1>>C=CC(=O)N1CCN(Cc2coc(C)n2)CC1,,ClCCl,,,,test
US20120244073A1,O=C(Cl)CF.c1ccc(Oc2ccccc2NCc2cccc3c2OCO3)cc1>>O=C(CF)N(Cc1cccc2c1OCO2)c1ccccc1Oc1ccccc1,,ClCCl,,,,test
US20090270395A1,CC(C)OC(=O)c1ccc(CCN[C@H](CCO)CO[Si](C)(C)C(C)(C)C)cc1.O=C(Cl)Cl>>CC(C)OC(=O)c1ccc(CCN2C(=O)OCC[C@@H]2CO[Si](C)(C)C(C)(C)C)cc1,,ClCCl,,c1ccncc1,,test
US04588749,CC(=O)Cc1ccc(C)cc1.NCC(O)c1ccccc1>>Cc1ccc(CC(C)NCC(O)c2ccccc2)cc1,,c1ccccc1,,,,test
US20160016951A1,Cn1cc(-c2ccc(-c3cncc4ccc(C(=O)O)cc34)cc2)cn1.NC1CC1>>Cn1cc(-c2ccc(-c3cncc4ccc(C(=O)NC5CC5)cc34)cc2)cn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(N(C)C)=[N+]1N=[N+]([O-])c2ncccc21.F[P-](F)(F)(F)(F)F,test
US20160130254A1,Brc1cccnc1.CCN(c1ccc(C#N)c(C(F)(F)F)c1)C1CCCC(=O)C1>>CCN(c1ccc(C#N)c(C(F)(F)F)c1)C1CCCC(O)(c2cccnc2)C1,,C1CCOC1,CCOCC,[Li]CCCC,,test
US20100137281A1,CCc1cc2c(=O)n(CC(=O)c3ccc(OC)cc3)c(=O)n(Cc3ccc(-c4ccccc4C#N)cc3)c2s1>>CCc1cc2c(=O)n(CC(=O)c3ccc(O)cc3)c(=O)n(Cc3ccc(-c4ccccc4C#N)cc3)c2s1,,ClCCl,,CCOC(C)=O,O,test
US20150065482A1,COc1ccc2[nH]nc(I)c2n1.N#C[Cu]>>COc1ccc2[nH]nc(C#N)c2n1,,CN1CCCC1=O,ClCCl,,,test
US20080275046A1,O=C(OCCCCl)c1ccc(OCCCCl)cc1F>>O=C(O)c1ccc(OCCCCl)cc1F,,CO,,[Na+].[OH-],,test
US20020151595A1,BrCc1ccccc1.C=CCc1cc(C#N)ccc1O>>C=CCc1cc(C#N)ccc1OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090048281A1,COc1cccc(C(O)(C(=O)O[C@H]2CN3CCC2CC3)c2cccc(OC)c2)c1.O=C(CBr)Nc1ccon1>>COc1cccc(C(O)(C(=O)O[C@H]2C[N+]3(CC(=O)Nc4ccon4)CCC2CC3)c2cccc(OC)c2)c1.[Br-],,CC#N,,,,test
US20060194859A1,CCOC(=O)C(CCc1ccccc1)CC(=O)c1ccc(Br)cc1.O=[N+]([O-])c1ccc(B(O)O)cc1>>CCOC(=O)C(CCc1ccccc1)CC(=O)c1ccc(-c2ccc([N+](=O)[O-])cc2)cc1,,C1COCCO1,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20130190249A1,COc1ccc(CN2C(=O)COC[C@H]2C(=O)OCc2ccccc2)cc1>>O=C1COC[C@@H](C(=O)OCc2ccccc2)N1,,CC#N,O,CCN(C(C)C)C(C)C,,test
US20070142461A1,O=C(O)C(O)c1ccccc1>>O=C(O)C(O)C1CCCCC1,[Rh],CC(=O)O,,CO,,test
US05958954,CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2ccc(C)nc2)=CC(C)(C)S3)cc1>>Cc1ccc(C2=CC(C)(C)Sc3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cn1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US06444662B1,CC(C)=CCC[C@]1(C)[C@@H](CC=C(C)C)C[C@@]2(CC=C(C)C)C(=O)[C@]1(C(=O)C(C)C)C(=O)C(CC=C(C)C)=C2O.[Na]>>CC(C)=CCC[C@]1(C)[C@@H](CC=C(C)C)C[C@@]2(CC=C(C)C)C(=O)[C@]1(C(=O)C(C)C)C(=O)C(CC=C(C)C)=C2O.[Na],,CO,,,,test
US04110445,CNC(=O)CCl.N#CNc1ccc(Cl)cc1>>CN1C(=N)N(c2ccc(Cl)cc2)CC1=O,,O,,[Na+].[OH-],,test
US20160272617A1,Cc1cc(C(=O)NC2CCC(N(C)C)CC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nc(C(F)(F)C(F)(F)C(F)(F)F)n[nH]3)cc2)cc1.Cl>>Cc1cc(C(=O)NC2CCC(N(C)C)CC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3nc(C(F)(F)C(F)(F)C(F)(F)F)n[nH]3)cc2)cc1.Cl,,C1COCCO1,,O=C(O)C(F)(F)F,,test
US20110009447A1,COC(=O)c1ccccc1C#Cc1ccncc1>>COC(=O)c1ccccc1CCc1ccncc1,[Pd],CCO,,,,test
US20120040949A1,CC1(C)COC(c2c(F)cc(F)cc2F)=N1.C[Mg]Br>>Cc1cc(F)cc(F)c1C1=NC(C)(C)CO1,,C1CCOC1,,,,test
US05610156,CCCCOc1ccc(C(=O)Cl)cc1.c1ccc2c(c1)Cn1cccc1CN2>>CCCCOc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1,,ClCCl,,CCN(CC)CC,[Na+].[OH-],test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1-c1ccc2c(c1)CCO2>>CCCC(C(=O)O)c1c(C)nc(-c2ccccc2)nc1-c1ccc2c(c1)CCO2,,CO,,[Na+].[OH-],,test
US05055464,NC(=O)CN1C(=O)[C@@H](N)[C@H](c2ccccc2)Cc2ccccc21.O=C(ON1C(=O)CCC1=O)c1cc2ccccc2[nH]1>>NC(=O)CN1C(=O)[C@@H](NC(=O)c2cc3ccccc3[nH]2)[C@H](c2ccccc2)Cc2ccccc21,,CN(C)C=O,,,,test
US20100056527A1,O=S(Cl)Cl.OCc1cc(Cl)cc2cc(-c3ccc(Cl)cc3Cl)oc12>>ClCc1cc(Cl)cc2cc(-c3ccc(Cl)cc3Cl)oc12,,ClCCl,,,,test
US20070244125A1,CS(=O)(=O)Cl.O=C(c1ccc2[nH]c(C(=O)N3CCC(F)(F)CC3)cc2c1)N1CCN(C2CCCC2)CC1>>CS(=O)(=O)n1c(C(=O)N2CCC(F)(F)CC2)cc2cc(C(=O)N3CCN(C4CCCC4)CC3)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20130158009A1,COC(=O)c1cnc(N2CCC(N3CC[C@H](Nc4ccc(S(C)(=O)=O)cc4F)C3=O)CC2)c(Cl)c1>>CS(=O)(=O)c1ccc(N[C@H]2CCN(C3CCN(c4ncc(C(=O)O)cc4Cl)CC3)C2=O)c(F)c1,,C1CCOC1,,[Li+].[OH-],,test
US04075001,CC[N+](CC)=C(Cl)Cl.N#CCC#N>>CCN(CC)C(Cl)=C(C#N)C#N,,Clc1ccccc1,,CCN(CC)CC,,test
US20140045901A2,CS(=O)(=O)c1ccc(-n2cncc2-c2ccccc2)cn1.O=C1CCC(=O)N1Cl>>CS(=O)(=O)c1ccc(-n2cnc(Cl)c2-c2ccccc2)cn1,CC(C)(C#N)N=NC(C)(C)C#N,C1CCOC1,,,,test
US20140121377A1,Nc1ccc(I)cn1.O=C(CBr)c1ccc(-n2ccnc2)nc1>>Ic1ccc2nc(-c3ccc(-n4ccnc4)nc3)cn2c1,,CC#N,,,,test
US20130053386A1,CCn1nc(-c2cccc(C(C)(C)NS(=O)(=O)CC(F)(F)F)c2)cc1Oc1ccc(C=O)cc1.NCC1CCCO1>>CCn1nc(-c2cccc(C(C)(C)NS(=O)(=O)CC(F)(F)F)c2)cc1Oc1ccc(CNCC2CCCO2)cc1,,CN(C)C=O,,,,test
US06500797B1,C=CC(C)(O)CCC=C(C)C.CC1(C)OC(=O)CC(=O)O1.O=C(Cl)c1ccc2ccccc2c1>>C=CC(C)(CCC=C(C)C)OC(=O)CC(=O)c1ccc2ccccc2c1,,C1CCOC1,O,[H-].[Na+],,test
US20130045964A1,CC(C)(O)CN.O=C(O)C(O)c1ccc(-c2noc(-c3noc(-c4ccccc4)c3C(F)(F)F)n2)cc1>>CC(C)(O)CNC(=O)C(O)c1ccc(-c2noc(-c3noc(-c4ccccc4)c3C(F)(F)F)n2)cc1,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04476308,CCOC(=O)CN1CCC(O)C1=O.C[C@H]1CCC[C@@H](C)N1CCN>>C[C@H]1CCC[C@@H](C)N1CCNC(=O)CN1CCC(O)C1=O,,CCOCC,,,,test
US20150252048A1,C=CC(=O)Nc1cccc(-c2nc(Nc3cccc(N4CCN(C(=O)OC(C)(C)C)CC4)c3)ncc2Cl)c1>>C=CC(=O)Nc1cccc(-c2nc(Nc3cccc(N4CCNCC4)c3)ncc2Cl)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020019424A1,Cc1ccc(S(=O)(=O)N2[C@@H](CCCCl)CC[C@H]2c2ccc(F)cc2)cc1.c1c[nH]cn1>>Cc1ccc(S(=O)(=O)N2[C@@H](CCCn3ccnc3)CC[C@H]2c2ccc(F)cc2)cc1,,ClC(Cl)Cl,,,,test
US06114332,C1CCOC1.CCc1ccc2nc3c(C(=O)O)cccc3cc2c1.CN(C)C=O.CN(CCCN)CCCN.O=C(n1ccnc1)n1ccnc1.c1c[n-]cn1>>CCc1ccc2nc3c(C(=O)NCCCN(C)CCCNC(=O)c4cccc5cc6cc(CC)ccc6nc45)cccc3cc2c1,,C1CCOC1,,,,test
US06605124B1,CC(=O)Nc1cccc2c(O)c(NC(=O)CCl)ccc12.Cn1ccnc1>>CC(=O)Nc1cccc2c(O)c(NC(=O)Cn3cc[n+](C)c3)ccc12.[Cl-],,C1COCCO1,,,,test
US20160264553A1,Cc1cccc(-c2ncccc2-c2ccc3nc[nH]c(=O)c3n2)n1.O=C(Cl)C(=O)Cl>>Cc1cccc(-c2ncccc2-c2ccc3ncnc(Cl)c3n2)n1,,ClCCl,,CN(C)C=O,Cl,test
US20090118300A1,CCOC(=O)C(=O)CBr.CCOc1cccc(NC(=N)c2ccc(C)cc2)c1>>CCOC(=O)c1cn(-c2cccc(OCC)c2)c(-c2ccc(C)cc2)n1,,C1COCCO1,,O=C([O-])O.[Na+],,test
US20050171356A1,CC(O)COc1c(Cl)cc(O)cc1Cl.ClCCC(Cl)(Cl)Cl>>OCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05155223,C1CNCCN1.O=C(O)c1cn(C2CC2)c2cc(F)c(F)cc2c1=O>>O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O,,O,,,,test
US20160016947A1,Cc1nc(C#N)ccc1Cl>>Cc1nc(CN)ccc1Cl,,CO,O,[BH4-].[Na+],,test
US20020016339A1,BrCc1ccccc1.OCc1cccnc1>>OCC1=CC=CN(Cc2ccccc2)C1.[Br-],,CCO,,,,test
US06242439B1,O=C(C[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)OCc1ccccc1>>N[C@H](CC(=O)O)Cc1ccccc1,,CO,,,,test
US06440899B1,CC1(C)CCS(=O)(=O)c2c1ccc(C(=O)C1=C(Cl)CCCC1=O)c2Cl.Sc1ccc(Cl)cc1>>CC1(C)CCS(=O)(=O)c2c1ccc(C(=O)C1=C(Sc3ccc(Cl)cc3)CCCC1=O)c2Cl,,C1CCOC1,,CCN(CC)CC,O,test
US20070203136A1,COC(=O)Cc1ccc2ncccc2c1.O>>COC(=O)Cc1ccc2c(c1)C=CCN2O,,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US06090820,CC(=O)OC(C)=O.NC[C@H]1CN(c2ccc(N3C[C@@H]4CN(C(=O)OCc5ccccc5)C[C@@H]4C3)c(F)c2)C(=O)O1>>CC(=O)NC[C@H]1CN(c2ccc(N3C[C@@H]4CN(C(=O)OCc5ccccc5)C[C@@H]4C3)c(F)c2)C(=O)O1,,ClCCl,,c1ccncc1,,test
US20120094958A1,N#Cc1ccc2cc([N+](=O)[O-])cc(-c3cccc4ccccc34)c2n1>>N#Cc1ccc2cc(N)cc(-c3cccc4ccccc34)c2n1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20080085905A1,BrBr.COC(=O)c1cnc(N2CCCCC2)cn1>>COC(=O)c1cnc(N2CCCCC2)c(Br)n1,,ClC(Cl)Cl,,ClCCl,O,test
US20120202856A1,Cc1oc(C(=O)O)nc1C(C)(C)C.O=C(Cl)C(=O)Cl>>Cc1oc(C(=O)Cl)nc1C(C)(C)C,,ClCCl,,CN(C)C=O,,test
US20160177118A1,CC(N)COCC(C)OCC(C)OCC(C)N.O=C(n1ccnc1)n1ccnc1>>CC(N)COCC(C)OCC(C)OCC(C)N.[N-]=C=O,,CCOC(C)=O,,O,,test
US20130109682A1,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.CCC1(O)C(O)CC(c2ccncc2[N+](=O)[O-])OC1C>>CCC1(O)C(C)OC(c2ccncc2[N+](=O)[O-])CC1O[Si](C)(C)C(C)(C)C,,ClCCl,,Cc1cccc(C)n1,,test
US20120270865A2,CCOC(=O)CCNC(=O)c1ccc(NC(c2oc3ccc(Cl)nc3c2C)C2CCCCC2)cc1>>Cc1c(C(Nc2ccc(C(=O)NCCC(=O)O)cc2)C2CCCCC2)oc2ccc(Cl)nc12,,CCO,,C1CCOC1,[Na+].[OH-],test
US05405851,Cc1ccc2ccc3nc(NC(=O)C(C)(C)C)[nH]c(=O)c3c2c1.O=C1CCC(=O)N1Br>>CC(C)(C)C(=O)Nc1nc2ccc3ccc(CBr)cc3c2c(=O)[nH]1,,c1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20050197357A1,CN1[C@@H]2CC=C[C@@]1(OC(=O)C(O)(c1ccccc1)c1ccccc1)CC2.COCCN(CCOC)S(F)(F)F>>CN1[C@@H]2CC=C[C@@]1(O)CC2.O=C([O-])C(F)(c1ccccc1)c1ccccc1,,ClC(Cl)Cl,,,,test
US20110105542A1,CCc1cccc(CC)c1NC(=O)c1nn(C)c2c1CCc1cnc(NC3CCNCC3)nc1-2.O=C(Cl)CCBr>>C=CC(=O)N1CCC(Nc2ncc3c(n2)-c2c(c(C(=O)Nc4c(CC)cccc4CC)nn2C)CC3)CC1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20130172329A1,CC#CC(=O)OCC.O/N=C(\Cl)c1ccc(F)cc1>>CCOC(=O)c1c(-c2ccc(F)cc2)noc1C,,CCOCC,,CCN(CC)CC,,test
US03962224,CC(=O)CCl.CCOP(=O)(OCC)C(NC=S)C(=O)OCC(Cl)(Cl)Cl>>CCOP(=O)(OCC)C(N=CSCC(C)=O)C(=O)OCC(Cl)(Cl)Cl,,CC(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US05508293,CCCO.Cc1cncc(C#N)c1>>CCCOC(=N)c1cncc(C)c1,,CCCO,,CC(=O)O,C[O-].[Na+],test
US20150258074A1,CC(C)(C)O.COc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(Cl)nc(C(=O)O)c12.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(Cl)nc(NC(=O)OC(C)(C)C)c12,,O,,CCN(CC)CC,,test
US20110257151A1,COC(=O)c1ccc2c(c1)CC(C)(C)C(c1ccccc1NS(C)(=O)=O)N2>>CC1(C)Cc2cc(C(=O)O)ccc2NC1c1ccccc1NS(C)(=O)=O,,C1CCOC1,CO,[Na+].[OH-],,test
US20100105921A1,CN(C)c1ccc(N=O)cc1.O=Cc1ccccc1>>CN(C)c1ccc(N(O)C(=O)c2ccccc2)cc1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20080153817A1,CCOC(=O)CC1CCCc2c1n(C(CO)c1ccc(C(F)(F)F)cc1)c1ccc(C(C)C)cc21.CI>>CCOC(=O)CC1CCCc2c1n(C(COC)c1ccc(C(F)(F)F)cc1)c1ccc(C(C)C)cc21,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20090306076A1,CC(C)CN(Cc1ccc2c(c1)C(O)CCCC2)C(=O)C1CN(C(=O)OC(C)(C)C)CCO1>>CC(C)CN(Cc1ccc2c(c1)CCCCC2)C(=O)C1CN(C(=O)OC(C)(C)C)CCO1,[Pd],CCO,,[H][H],,test
US20110118261A1,C1CCN(C2CCNCC2)C1.O=c1cc(OCc2ccc(Cl)cn2)ccn1-c1ccc(F)nc1>>O=c1cc(OCc2ccc(Cl)cn2)ccn1-c1ccc(N2CCC(N3CCCC3)CC2)nc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090054435A1,CCOC(=O)c1c(C)cc(OC)cc1OCOC>>COCOc1cc(OC)cc(C)c1C(=O)O,,O,,CCO,[Na+].[OH-],test
US20030119857A1,CCOc1cc(Cc2cnc(N)nc2N)cc2[nH]ccc12.CN(C)S(=O)(=O)Cl>>CCOc1cc(Cc2cnc(N)nc2N)cc2c1ccn2S(=O)(=O)N(C)C,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20130150368A1,CC(C)(CNc1cnc(-c2cccc(C#N)c2)nn1)c1ccc(F)cc1.OO>>CC(C)(CNc1cnc(-c2cccc(C(N)=O)c2)nn1)c1ccc(F)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150111870A1,COC(=O)C(C(=O)OC)C1CCCCC1>>O=C(O)C(C(=O)O)C1CCCCC1,,C1CCOC1,,[Na+].[OH-],,test
US05006570,NCC1CCCN1CC1=CCCCC1.O=C(Cl)c1cc(Cl)cc2c1OCCC2>>O=C(NCC1CCCN1CC1=CCCCC1)c1cc(Cl)cc2c1OCCC2,,CCC(C)=O,,,,test
US20110301155A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CS(=O)(=O)c1ccc(Oc2cc(-c3ncccc3Cl)cc3c(Br)n[nH]c23)cc1>>CC(C)(C)OC(=O)n1nc(Br)c2cc(-c3ncccc3Cl)cc(Oc3ccc(S(C)(=O)=O)cc3)c21,CN(C)c1ccncc1,CC#N,,,,test
US20120309673A1,CC(C)(C)OC(=O)NC(CC1(F)CCCC1)C(=O)NC1(C(O)C(=O)O)CCC1.Nc1cc[nH]n1>>CC(C)(C)OC(=O)NC(CC1(F)CCCC1)C(=O)NC1(C(O)C(=O)Nc2cc[nH]n2)CCC1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100093757A1,COC(=O)[C@H](CCS(C)(=O)=O)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>COC(=O)[C@@H](O)CCS(C)(=O)=O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040157839A1,CC(C)(C)OC(=O)N1CC2CC1CN2.Cc1nc(Cl)n2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2n1>>Cc1nc(N2C[C@@H]3C[C@H]2CN3C(=O)OC(C)(C)C)n2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04945160,CC(=O)N1CCC(=O)CC1.CCCC[SnH](CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)C1(O)CCN(C(C)=O)CC1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20150175594A1,CC(C)(C)OC(=O)Nc1sc2c(c1-c1nc(C3CC3)no1)CCCC2.O=C1OC(=O)C2=C1CCC2>>O=C(O)C1=C(C(=O)Nc2sc3c(c2-c2nc(C4CC4)no2)CCCC3)CCC1,CN(C)c1ccncc1,CC#N,ClCCl,O=C(O)C(F)(F)F,,test
US20070105904A1,C=O.CCCC[SnH](CCCC)CCCC>>CCCC[Sn](CO)(CCCC)CCCC,,C1CCOC1,O,CC(C)NC(C)C,[Li]CCCC,test
US04254274,C1=C(N2CCOCC2)CCC1.CCOC(=O)C(C)c1ccc(C=O)cc1>>CCOC(=O)C(C)c1ccc(C=C2CCCC2=O)cc1,,c1ccccc1,,Cl,O,test
US20030187014A1,CCI.Cc1nn(-c2ccccn2)c2[nH]c3ccccc3c(=O)c12>>CCOc1c2ccccc2nc2c1c(C)nn2-c1ccccn1,,CN(C)C=O,,[H-].[Na+],,test
US20160122364A1,Brc1cnc2c(N3CCOCC3)snc2c1.COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1O>>COc1cc(-c2cnc3c(N4CCOCC4)snc3c2)ccc1O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20050090559A1,CC(C)(CC(O)(C=O)C(F)(F)F)c1cccc2c1OCO2.Cc1ncc2c(N)ccc(F)c2n1>>Cc1ncc2c(N=CC(O)(CC(C)(C)c3cccc4c3OCO4)C(F)(F)F)cccc2n1,,Cc1ccccc1,,CCCCCC,CCOC(C)=O,test
US04352815,CCOC(=O)c1ncn2c1[C@@H]1CCCN1C(=O)c1ccccc1-2.O=[N+]([O-])O>>CCOC(=O)c1ncn2c1[C@@H]1CCCN1C(=O)c1cc([N+](=O)[O-])ccc1-2,,O=S(=O)(O)O,,N,,test
US20110144105A1,COc1cnc2[nH]c(C(=CC3CCCC3)c3ccc(S(C)(=O)=O)cc3)cc2c1>>COc1cnc2[nH]c(C(CC3CCCC3)c3ccc(S(C)(=O)=O)cc3)cc2c1,[Pd],CO,,[H][H],,test
US20080249091A1,CCOC(=O)c1c(CCC#N)c2cc(O)ccc2n1-c1ccc(OC(C)C)cc1.FC(F)(F)c1ccc(Cl)nc1>>CCOC(=O)c1c(CCC#N)c2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1-c1ccc(OC(C)C)cc1,,CCOC(C)=O,CN(C)C=O,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US20040248961A1,O=C(O)[C@@H]1C[C@@H](O)CN1.O=[N+]([O-])c1ccc(F)cc1>>O=C(O)C1CC(O)CN1c1ccc([N+](=O)[O-])cc1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20110319378A1,C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)CC(C)=O)C1=O.C[Mg]Br>>C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)CC(C)(C)O)C1=O,,C1CCOC1,Cc1ccccc1,,,test
US20120328569A1,CCOC(=O)c1c(-c2ccc(F)cc2)oc2cc(N3CCOC3=O)c(Br)cc12>>O=C(O)c1c(-c2ccc(F)cc2)oc2cc(N3CCOC3=O)c(Br)cc12,,C1COCCO1,O,[Li+].[OH-],,test
US20080064690A1,CS(=O)(=O)c1cccc(N)c1.O=C(Cl)c1cnn(-c2ccc(Cl)cc2)c1C(F)(F)F>>CS(=O)(=O)c1cccc(NC(=O)c2cnn(-c3ccc(Cl)cc3)c2C(F)(F)F)c1,,CC#N,,CCN(CC)CC,Cl,test
US20030114666A1,BrC1CC1.COCNC(=O)C1CCN(C(=O)OCc2ccccc2)C1>>O=C(C1CC1)C1CCN(C(=O)OCc2ccccc2)C1,,C1CCOC1,CCOC(C)=O,[Li]CCCC,,test
US20110144085A1,CC(C)(C)OC(=O)N1CCCC2(CC1)CO2.Oc1cc(F)cc2ccc(-c3nnc4ccccn34)nc12>>CC(C)(C)OC(=O)N1CCCC(O)(COc2cccc3ccc(-c4nnc5ccccn45)nc23)CC1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06187801B1,Cc1nc2c(s1)Cc1cc(Cl)ccc1-2>>Cc1nc2c(s1)Cc1cc(Cl)ccc1-2,,CCOC(C)=O,,Cl,,test
US05574153,CCOC(=O)CBr.COc1cccc(C=O)c1O>>COc1cccc(C=O)c1OCC(=O)O,,CC#N,,,,test
US20140194469A1,CC(C)(C)[Si](C)(C)Cl.[Li]OC(=O)CCCO>>[Li]OC(=O)CCCO[Si](C)(C)C(C)(C)C,,CN(C)C=O,,O,c1c[nH]cn1,test
US05610174,COc1ccc2c(c1N)CCCC2C#N.CS(=O)(=O)Cl>>COc1ccc2c(c1NS(C)(=O)=O)CCCC2C#N,,CCOC(C)=O,c1ccncc1,,,test
US20090306041A1,C1COCCN1.CC(C)(C)OCC(=O)O>>CC(C)(C)OCC(=O)N1CCOCC1,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20070249642A1,Cc1nc(C)c(-c2c[nH]c(=O)[nH]c2=O)o1.ClCCCCBr>>Cc1nc(C)c(-c2cn(CCCCCl)c(=O)[nH]c2=O)o1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050054657A1,CC(C)(C)OC(=O)Nc1ccc2c(c1)Sc1cccc(B3OC(C)(C)C(C)(C)O3)c1S2.O=c1cc(Cl)oc(N2CCOCC2)c1>>CC(C)(C)OC(=O)Nc1ccc2c(c1)Sc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20100144727A1,CN(C(=O)OC(C)(C)C)C(CO)C(=O)NCc1cccc(C(F)(F)F)c1Cl>>CN[C@@H](CO)C(=O)NCc1cccc(C(F)(F)F)c1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060004084A1,Nc1ccc2c(c1)C(=C1C(=O)Nc3ccc(Cl)cc31)OC2.O=C(Cl)CCBr>>C=CC(=O)Nc1ccc2c(c1)C(=C1C(=O)Nc3ccc(Cl)cc31)OC2,,C1CCOC1,,CCN(CC)CC,O,test
US20060142372A1,CN(CCNc1ccc2oc(CO)cc2c1)C(=O)OC(C)(C)C>>CNCCNc1ccc2oc(CO)cc2c1,,C1COCCO1,Cl,,,test
US20050203089A1,CC(C)[C@H](N)C(=O)OCc1ccccc1.O=C(Cl)OCCl>>CC(C)[C@H](NC(=O)OCCl)C(=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
US20080039437A1,CCOC(=O)c1cc(C#N)c(=O)[nH]c1C(F)(F)F.O=C(Cl)C(=O)Cl>>CCOC(=O)c1cc(C#N)c(Cl)nc1C(F)(F)F,,CN(C)C=O,,,,test
US20080214598A1,CN(Cc1ccc(Cl)c(CO)c1)C(=O)OC(C)(C)C>>CN(Cc1ccc(Cl)c(C=O)c1)C(=O)OC(C)(C)C,O=[Mn]=O,CC#N,,,,test
US20160002188A1,C[C@@H]1CNCCN1C(=O)OC(C)(C)C.Cn1cnc2cc(-c3ccc(C(=O)O)cc3)ccc21>>C[C@@H]1CN(C(=O)c2ccc(-c3ccc4c(c3)ncn4C)cc2)CCN1C(=O)OC(C)(C)C,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05843973,CC(O[Si](C)(C)C(C)(C)C)[C@@H]1CC[C@@H](CNC(=O)OC(C)(C)C)CC1>>CC(O)[C@@H]1CC[C@@H](CNC(=O)OC(C)(C)C)CC1,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20080004271A1,NC(=O)c1sc2nc(NC3CC3)nc(-c3cccc(N)c3)c2c1N.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>NC(=O)c1sc2nc(NC3CC3)nc(-c3cccc(NC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)c3)c2c1N,,C1CCOC1,,,,test
US20060178378A1,NC(=O)c1c(Cl)cncc1Cl>>N#Cc1c(Cl)cncc1Cl,,O=P(Cl)(Cl)Cl,,,,test
US20120302610A1,CCOC(=O)CCNC(=O)c1ccc(-c2cc(OC)ccc2CNc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)cn1>>COc1ccc(CNc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)c(-c2ccc(C(=O)NCCC(=O)O)nc2)c1,,CO,,C1CCOC1,[Na+].[OH-],test
US20150005279A1,CC(C)(C)OC(=O)N1CC(Oc2ccc(C(N)=O)c3[nH]ccc23)C1.Cl>>Cl.NC(=O)c1ccc(OC2CNC2)c2cc[nH]c12,,CO,,,,test
US04514490,CCCCCCCCCCCCC(Br)C(=O)OCC.Oc1ccc2c(c1)OCO2>>CCCCCCCCCCCCC(Oc1ccc2c(c1)OCO2)C(=O)O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04311705,CCCCI.CCOC(=O)C(CC(C)C(=O)OCc1ccccc1)C(=O)OCC>>CCCCC(CC(C)C(=O)OCc1ccccc1)(C(=O)OCC)C(=O)OCC,,CCO,,[Na],,test
US20160206616A1,CCOC(=O)CC(C)[C@H]1CC(F)(F)CN1C(=O)OC(C)(C)C>>CC(CC(=O)O)[C@H]1CC(F)(F)CN1C(=O)OC(C)(C)C,,CCO,,O,[Li]O,test
US20050137226A1,Cl.Fc1ccc(Oc2ccc(OC3CN4CCC3CC4)cc2)cc1>>Cl.Fc1ccc(Oc2ccc(OC3CN4CCC3CC4)cc2)cc1,,CCOC(C)=O,,C1COCCO1,,test
US20110118245A1,CC(C)(C)c1cc(NC(=O)Nc2cc(O)ccc2F)n(-c2ccccc2)n1.COc1cc2ncnc(Cl)c2cc1OC>>COc1cc2ncnc(Oc3ccc(F)c(NC(=O)Nc4cc(C(C)(C)C)nn4-c4ccccc4)c3)c2cc1OC,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100160411A1,O=C(OO)c1cccc(Cl)c1.O=C1c2ccccc2C(=O)N1CC1CSc2cc(F)cc(-c3c(Cl)cccc3Cl)c2O1>>O=C1c2ccccc2C(=O)N1CC1CS(=O)c2cc(F)cc(-c3c(Cl)cccc3Cl)c2O1,,CCOC(C)=O,,,,test
US20160200688A1,COc1cc([N+](=O)[O-])c(C#N)cc1OCc1ccccc1>>COc1cc(N)c(C#N)cc1O,[Pd],CO,,,,test
US20160009710A1,COC(=O)c1cc(Cl)ncc1Br>>OCc1cc(Cl)ncc1Br,,C1CCOC1,,CO,[BH4-].[Li+],test
US20050026989A1,COC(=O)c1c[nH]c2cc(F)ccc12.Clc1ccnc2ccccc12>>COC(=O)c1cn(-c2ccnc3ccccc23)c2cc(F)ccc12,,CN(C)C=O,,O,[H-].[Na+],test
US20150238473A1,COc1ccc(CCBr)cc1.OC(c1ccccc1)(c1ccccc1)C1CCNCC1>>COc1ccc(CCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1,,CC#N,,,,test
US20150080369A1,CCc1ccc(NCC(C)C)cc1.COC(=O)c1cc(S(=O)(=O)Cl)ccc1O>>CCc1ccc(N(CC(C)C)S(=O)(=O)c2ccc(O)c(C(=O)OC)c2)cc1,,c1ccncc1,,,,test
US20090163472A1,BrP(Br)Br.OCC1(Br)C=CC=C(F)C1>>FC1=CC=CC(Br)(CBr)C1,,ClC(Cl)Cl,,c1ccncc1,,test
US06350749B1,CC#CCN.Cc1ccccc1C1CC(=O)CC(=O)C1>>Cc1ccccc1C1CC(=O)c2c(C)ccnc2C1,,CCN(CC)CC,,C1CCOC1,Cl,test
US20120258952A1,CCOC(=O)c1cnc(C)s1.Cc1nc(Cn2nc(I)c3c([N+](=O)[O-])cccc32)cs1>>Cc1ncc(Cn2nc(I)c3c(N)cccc32)s1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20030008768A1,Cc1ccccc1B(O)O.O=[N+]([O-])c1ccc(Cl)cc1>>Cc1ccccc1-c1ccc([N+](=O)[O-])cc1,,C1CCOC1,,[F-].[K+],,test
US20110301175A1,CCOC(=O)C1CCNCC1.Cc1ccc(Nc2ncc(-c3ccc(OC(F)F)cc3)cn2)cc1CCOS(C)(=O)=O>>CCOC(=O)C1CCN(CCc2cc(Nc3ncc(-c4ccc(OC(F)F)cc4)cn3)ccc2C)CC1,,CN(C)C=O,,,,test
US20110046122A1,O=C1NC(c2cc(Br)ccc2F)(C2CC2)CO1>>NC(CO)(c1cc(Br)ccc1F)C1CC1,,CCO,O,[Li+].[OH-],,test
US20040127538A1,O=C(O)c1ccc2c(c(-c3cccc(F)c3)nn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1F.OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>O=C(Nc1ccc2c(c(-c3cccc(F)c3)nn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1F)OCc1ccccc1,,Cc1ccccc1,O,CCN(CC)CC,,test
US20160115158A1,CCS(=O)(=O)c1cnc(NS(=O)(=O)Cc2cccc(Cl)c2)c(OC)n1>>CCS(=O)(=O)c1cnc(NS(=O)(=O)Cc2cccc(Cl)c2)c(O)n1,,ClCCl,,BrB(Br)Br,,test
US20110319393A1,CC(C)(C)OC(=O)COC1CCN(c2ccc(C(F)(F)F)cc2)CC1>>O=C(O)COC1CCN(c2ccc(C(F)(F)F)cc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040186108A1,Cc1cccc(CC(=O)O)c1[N+](=O)[O-]>>Cc1cccc(CCO)c1[N+](=O)[O-],,C1CCOC1,,,,test
US20060046980A1,CCOP(OCC)OCC.COc1ccc(Oc2c(Cl)cc(CBr)cc2Cl)cc1C(C)C>>CCOP(=O)(Cc1cc(Cl)c(Oc2ccc(OC)c(C(C)C)c2)c(Cl)c1)OCC,,CCOC(C)=O,CN(C)C=O,,,test
US20130079346A1,COC(=O)c1cc(C(N)=S)ccc1-c1ccccc1[N+](=O)[O-].O=C(CBr)c1ccccc1C(F)(F)F>>O=C(O)c1cc(-c2nc(-c3ccccc3C(F)(F)F)cs2)ccc1-c1ccccc1[N+](=O)[O-],,O,,,,test
US20100286132A1,CCOC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)cn1>>Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)nc1,,C1CCOC1,O,[Li+].[OH-],,test
US20090042872A1,CN(CCO)C(=O)OC(C)(C)C.COC(OC)c1cc(Br)ccc1O>>COC(OC)c1cc(Br)ccc1OCCN(C)C(=O)OC(C)(C)C,,c1ccccc1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080004271A1,CCOC(=O)CC#N.COc1cc(Cl)cc(C=O)c1.N=C(N)NC1CC1>>COc1cc(Cl)cc(-c2nc(NC3CC3)[nH]c(=O)c2C#N)c1,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US05026856,Fc1ccc2c(c1)CNC2.Nc1c(F)c(F)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1>>Nc1c(F)c(N2Cc3ccc(F)cc3C2)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20050154042A1,N#CC(=Cc1ccc(F)cc1)c1ccccn1.[C-]#[N+]CC(=O)OCC>>CCOC(=O)c1[nH]cc(-c2ccccn2)c1-c1ccc(F)cc1,,C1CCOC1,O,CCOC(C)=O,CC(C)(C)[O-].[K+],test
US20060293341A1,CC[Mg]Br.N#Cc1ccccn1.O=C(O)CC(O)(CC(=O)O)C(=O)O>>CCC(=O)c1ccccn1,,C1CCOC1,,CCOCC,,test
US20040038965A1,C[C@@H]1CC[C@H](NC(=O)C2(NC(=O)OC(C)(C)C)CCCCC2)[C@@H](O)CN1S(=O)(=O)c1ccccn1>>C[C@@H]1CC[C@H](NC(=O)C2(N)CCCCC2)[C@@H](O)CN1S(=O)(=O)c1ccccn1,,C1COCCO1,CO,Cl,,test
US20130116262A1,Nc1ncc(Cl)cc1Br.O=CCCl>>Clc1cc(Br)c2nccn2c1,,CCO,,,,test
US20090247746A1,CCOC(=O)c1cc2cccc(N)c2[nH]1.O=C(O)c1cccs1>>CCOC(=O)c1cc2cccc(NC(=O)c3cccs3)c2[nH]1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020068753A1,BrCCCCCCOC1CCNCC1.O=S(=O)(Cl)Nc1ccccc1>>O=S(=O)(Nc1ccccc1)N1CCC(OCCCCCCBr)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20110076291A1,C[C@H]1CN(c2ccc3c(n2)-c2sc(-c4ncnn4-c4ccc(F)cc4F)cc2CCO3)C[C@@H](C)N1.FCCBr>>C[C@H]1CN(c2ccc3c(n2)-c2sc(-c4ncnn4-c4ccc(F)cc4F)cc2CCO3)C[C@@H](C)N1CCF,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04845219,CCCCCCCCCCCCCCCCCCOCC(CS(=O)(=O)CCCOS(C)(=O)=O)OC.CN(C)C>>CCCCCCCCCCCCCCCCCCOCC(CS(=O)(=O)CCC[N+](C)(C)C)OC.CS(=O)(=O)[O-],,Cc1ccccc1,,,,test
US20130184254A1,NNc1c(F)cccc1F.O=Cc1c(I)ccnc1F>>Fc1cccc(F)c1-n1ncc2c(I)ccnc21,,CN1CCCC1=O,,,,test
US05231102,COC(=O)[C@H]1C[C@H](N)c2c(Cl)cc(Cl)cc2N1.O=C1CCC(=O)O1>>COC(=O)[C@H]1C[C@H](NC(=O)CCC(=O)O)c2c(Cl)cc(Cl)cc2N1,,CCOC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100256143A1,CC(C)(C)OC(=O)N1CC2CNCC2C1.Clc1cc(N2CCOCC2)nc(CBr)n1>>CC(C)(C)OC(=O)N1CC2CN(Cc3nc(Cl)cc(N4CCOCC4)n3)CC2C1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20140148487A1,CCCCCCCCCCCCCCBr.Cc1cccc(O)c1C>>CCCCCCCCCCCCCCOc1cccc(C)c1C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04369186,CC(C)NC=O.ClC1=NC(=C(Cl)Cl)N=C1Cl.O>>CC(C)N(C=O)C(=O)c1nc(Cl)c(Cl)[nH]1,,CC#N,,,,test
US07060425B1,CCC(C)(C)c1cccc(C(C)(C)CC)c1O.O=CC(=O)O>>CCC(C)(C)c1cc2c(c(C(C)(C)CC)c1)OC(=O)C2O,,ClCCCl,O,Cc1ccc(S(=O)(=O)O)cc1,,test
US04914207,CCOP([O-])(=S)SCC.COc1ccccc1C#N>>COc1ccccc1C(N)=S,,CCOC(C)=O,,Cl,,test
US20040077669A1,CCC#CCOc1cc(Cl)ncn1.Oc1cccc(F)c1F>>CCC#CCOc1cc(Oc2cccc(F)c2F)ncn1,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20130150343A1,CC(C)[Si](OS(=O)(=O)C(F)(F)F)(C(C)C)C(C)C.OC[C@H]1CCN(c2nnc3ccc(F)cn23)C1>>CC(C)[Si](OC[C@H]1CCN(c2nnc3ccc(F)cn23)C1)(C(C)C)C(C)C,,ClCCl,,CCN(CC)CC,,test
US20040214822A1,CN(C)C1(C#N)CCC2(CC1)OCCO2.Fc1ccccc1CCl>>CN(C)C1(Cc2ccccc2F)CCC2(CC1)OCCO2,,CCOCC,,[Mg],[Cl-].[NH4+],test
US20150175557A1,Cc1cc(C(F)(F)F)c(CNC(=O)OC(C)(C)C)cn1.O=C(OO)c1cccc(Cl)c1>>Cc1cc(C(F)(F)F)c(CN)c[n+]1[O-],,CO,ClCCl,C1COCCO1,Cl,test
US20100298324A1,COc1ccc(-n2c(=S)[nH]c3cc(C(=O)O)c(F)cc3c2=O)nc1OC.NCc1ccc(Cl)cc1>>COc1ccc(-n2c(=S)[nH]c3cc(C(=O)NCc4ccc(Cl)cc4)c(F)cc3c2=O)nc1OC,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080125423A1,C/C=C/C(=O)OC(=O)/C=C/C.CN(Cc1cc2ccccc2n1C)C(=O)/C=C/c1ccc(N)nc1>>C/C=C/C(=O)Nc1ccc(/C=C/C(=O)N(C)Cc2cc3ccccc3n2C)cn1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20060135447A1,CI.COC(=O)c1c(O)cnc2ccccc12>>COC(=O)c1c(OC)cnc2ccccc12,,CC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20110251190A1,CC1(C)OB(C2=CCCOC2)OC1(C)C.NC1=N[C@@]2(CS1)c1cc(-c3cncc(F)c3)ccc1Oc1ncc(Br)cc12>>NC1=N[C@@]2(CS1)c1cc(-c3cncc(F)c3)ccc1Oc1ncc(C3=CCCOC3)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,O,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US04351842,CCC(=O)c1cc2ccccc2cc1C(=O)O>>CCC(O)c1cc2ccccc2cc1CO,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20020035272A1,CCCCc1oc2ccccc2c1C(=O)c1ccc(O)cc1>>CCCCc1oc2ccccc2c1C(O)c1ccc(O)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060142286A1,Cl[Mg]c1ccccc1.ON1CCCCC1>>ON1CCCCC1c1ccccc1,O=[Mn]=O,ClCCl,,[Cl-].[NH4+],,test
US05204365,CC(C(=O)O)c1cccc(C(=CCO)c2ccccc2)c1.O=S(Cl)Cl>>CC(C(=O)O)c1cccc(C(=CCCl)c2ccccc2)c1,,ClCCl,,,,test
US04215123,CCN.COC(=O)c1ccc(C)nc1Cl>>CCNc1nc(C)ccc1C(=O)OC,,CCO,,,,test
US04123250,CO.Cc1cc([N+](=O)[O-])c(NC(C)C)c([N+](=O)[O-])c1Cl>>COc1c(C)cc([N+](=O)[O-])c(NC(C)C)c1[N+](=O)[O-],,CO,,C[O-].[Na+],,test
US20060074056A1,C1COCCN1.O=[N+]([O-])c1ccc(Oc2ccnc3cc(-c4ccc(CCl)cc4)sc23)c(F)c1>>O=[N+]([O-])c1ccc(Oc2ccnc3cc(-c4ccc(CN5CCOCC5)cc4)sc23)c(F)c1,,CN(C)C=O,,,,test
US20100016396A1,CCOC(=O)c1cc(O)n(C)n1.CN(C)C=O.O=P(Cl)(Cl)Cl>>CCOC(=O)c1nn(C)c(Cl)c1C=O,,O,,O=C([O-])O.[Na+],,test
US20070244103A1,C1CCOC1.CN(C)c1ccncc1.Cc1ccc(S(=O)(=O)Cl)cc1.ClCCl.Oc1cc2ccccc2nc1O>>COc1ccc2ncc(Cl)c(C(O)COS(=O)(=O)c3ccc(C)cc3)c2c1,CN(C)c1ccncc1,,,CCN(CC)CC,,test
US20100137278A1,COC(=O)N1CCC(c2nccnc2F)CC1.O=C(c1ccc(O)cc1)c1nc2ccccc2[nH]1>>COC(=O)N1CCC(c2nccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)CC1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020193367A1,Cc1noc(-c2cccc(C(=O)CC(=O)Nc3cc(Cl)c(N(C)C)cc3NC(=O)OC(C)(C)C)c2)c1COC1CCCCO1>>Cc1noc(-c2cccc(C3=Nc4cc(N(C)C)c(Cl)cc4NC(=O)C3)c2)c1CO,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100113450A1,NCCCC(=O)O.O=C(Cl)c1ccccc1>>O=C(O)CCCNC(=O)c1ccccc1,,O,,Cl,[Na+].[OH-],test
US20080115247A1,CS(=O)(=O)Oc1ccc(O)cc1.Cc1ccc(S(=O)(=O)OCCc2ccc(NC(=O)OC(C)(C)C)cc2)cc1>>CC(C)(C)OC(=O)Nc1ccc(CCOc2ccc(OS(C)(=O)=O)cc2)cc1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US05374772,CC(=O)OCCl.CCCCCCCCCCOc1cc(OCCCCCCc2cccc(OCc3ccccc3)c2OCc2ccccc2)cc(C(=O)O)c1>>CCCCCCCCCCOc1cc(OCCCCCCc2cccc(OCc3ccccc3)c2OCc2ccccc2)cc(C(=O)OCOC(C)=O)c1,,CC(C)=O,CN(C)C=O,CCN(CC)CC,[I-].[Na+],test
US20060217372A1,NC(=O)c1ccc(Oc2ccc3c(c2)CCN(C(=O)C(F)(F)F)CC3)nc1>>NC(=O)c1ccc(Oc2ccc3c(c2)CCNCC3)nc1,,CO,N,,,test
US20040235886A1,BrBr.Nc1ccc(-c2cccnc2)cc1[N+](=O)[O-]>>Nc1c(Br)cc(-c2cccnc2)cc1[N+](=O)[O-],,CC(=O)O,,,,test
US20050032830A1,Cc1nc(Cl)c([N+](=O)[O-])c(NCCCCO)c1C.Oc1ccccc1>>Cc1nc(Oc2ccccc2)c([N+](=O)[O-])c(NCCCCO)c1C,,C1COCCO1,,[H-].[Na+],,test
US06107329,COC(=O)[C@@H](N)Cc1c[nH]c2ccccc12.O=C(O)c1cc2cc(Cl)ccc2[nH]1>>COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)c1cc2cc(Cl)ccc2[nH]1,,CN(C)C=O,,Cl,,test
US20020193385A1,CC(C)(O)c1ccn2ccnc2n1.CCN(CC)S(F)(F)F>>CC(C)(F)c1ccn2ccnc2n1,,ClCCl,,,,test
US20090176804A1,NCc1ccc(Cl)cc1Cl.O=C(O)CCC(=O)c1ccc(Cl)c(S(=O)(=O)Cl)c1>>O=C(O)CCC(=O)c1ccc(Cl)c(S(=O)(=O)NCc2ccc(Cl)cc2Cl)c1,,ClCCl,,CO,Cl,test
US20090163472A1,CC(C)(C)OC(=O)N1C[C@H](NCc2ccccc2)[C@@H](O)C1.O=[N+]([O-])c1cc(Br)ccc1F>>CC(C)(C)OC(=O)N1C[C@H](Nc2ccc(Br)cc2[N+](=O)[O-])[C@@H](O)C1,,CCOC(C)=O,,CCN(CC)CC,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Cc1ccc(N)cc1>>COc1ccc2nc(Nc3ccc(C)cc3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US20100022484A1,CC(=O)CC(=O)C(F)(F)F.COC(=O)/C=C(/C)N.Cc1cc(=O)c2cccc(C=O)c2o1>>COC(=O)C1=C(C)NC(C)=C(C(=O)C(F)(F)F)C1c1cccc2c(=O)cc(C)oc12,,CC(C)O,,CC(=O)O,,test
US20120040985A1,COc1cc(C(C)(C)C(=O)NNC(=O)OC(C)(C)C)ccc1Cl.Cl>>COc1cc(C(C)(C)C(=O)NN)ccc1Cl.Cl,,CCOC(C)=O,CCOCC,,,test
US05126071,CCCCC(CC(=O)O)C(F)(F)F>>CCCCC(CCO)C(F)(F)F,,CCOCC,,[H-].[Na+],,test
US20140249104A1,C#CCOC1CCN(C(=O)OC(C)(C)C)CC1.Cl>>C#CCOC1CCNCC1.Cl,,C1COCCO1,,,,test
US20130065900A1,COc1cc(CCN(Cc2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)cc2)C(=O)OC(C)(C)C)c(Cl)cc1N.N#Cc1cnc(NC(=O)Oc2ccccc2)cn1>>COc1cc(CCN(Cc2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)cc2)C(=O)OC(C)(C)C)c(Cl)cc1NC(=O)Nc1cnc(C#N)cn1,,CN(C)C=O,O,,,test
US04923869,CC(C)O.CC1CC(=O)NN=C1c1ccc(NC(=O)c2cccnc2)c(N)c1>>CC1CC(=O)NN=C1c1ccc2nc(-c3cccnc3)[nH]c2c1.O.O,,CC(C)O,,Cl,,test
US20030207877A1,CN1C(=O)Cn2cc(C(=O)NCc3ccc(Cl)cc3)c(=O)c3cc(CCl)cc1c32.CNCC(O)c1cccc(OC)c1>>COc1cccc(C(O)CN(C)Cc2cc3c4c(c2)c(=O)c(C(=O)NCc2ccc(Cl)cc2)cn4CC(=O)N3C)c1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,CN(C)C=O,test
US20120083488A1,CC1(C)c2cc(OCC(=O)O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21.N#CCCN>>CC1(C)c2cc(OCC(=O)NCCC#N)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20060205807A1,COC(=O)c1ccc(F)c2c1C(O)C(N)CO2.O=C(n1ccnc1)n1ccnc1>>COC(=O)c1ccc(F)c2c1C1OC(=O)NC1CO2,,CC#N,,CCN(CC)CC,Cl,test
US20130178459A1,C[C@H](CO)c1ccc(Br)cc1F.O=C1NC(=O)c2ccccc21>>C[C@H](CN1C(=O)c2ccccc2C1=O)c1ccc(Br)cc1F,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120258948A1,CC(=O)c1ccc(-c2ccn(CCC(C)(C(=O)NO)S(C)(=O)=O)c(=O)c2)cc1.CON>>CO/N=C(\C)c1ccc(-c2ccn(CCC(C)(C(=O)NO)S(C)(=O)=O)c(=O)c2)cc1,,CCO,,Cl,CC(=O)[O-].[Na+],test
US06495542B1,Cc1ccc(S(=O)(=O)Cl)cc1.ON=C1CCCc2ccncc21>>Cc1ccc(S(=O)(=O)ON=C2CCCc3ccncc32)cc1,,CC(C)=O,,[Na+].[OH-],,test
US20090012097A1,BrBr.COC(=O)C(C)(C)Oc1ccc2cnccc2c1>>COC(=O)C(C)(C)Oc1ccc2cnccc2c1Br,,ClCCl,,,,test
US20040106650A1,COC(=O)[C@@H]1CC(=O)N(c2ccc(OCc3ccc(F)cc3)cc2)C1>>O=C(O)[C@@H]1CC(=O)N(c2ccc(OCc3ccc(F)cc3)cc2)C1,,C1COCCO1,,Cl,,test
US20110172221A1,CC[Mg]Br.O=Cc1cc(Br)ccc1F>>CCC(O)c1cc(Br)ccc1F,,CCOCC,,O,,test
US20160185779A1,O=C(O)C1CC1c1ccccc1.c1ccc(-c2n[nH]c3c2CNCC3)cc1>>O=C(C1CC1c1ccccc1)N1CCc2n[nH]c(-c3ccccc3)c2C1,,ClCCl,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070032489A1,CCc1cc(-c2nnc(C)o2)c(C)nc1OC>>CCc1cc(-c2nnc(C)o2)c(C)[nH]c1=O,,CC#N,,C[Si](C)(C)Cl,[I-].[Na+],test
US20150148536A1,Nc1ccccc1-c1ccccc1.O=C(Cl)c1ccc(CCl)cc1>>O=C(Nc1ccccc1-c1ccccc1)c1ccc(CCl)cc1,,ClCCl,,c1ccncc1,,test
US20070287716A1,O=[N+]([O-])c1cccc(Cc2ccccc2C(F)(F)F)c1>>Nc1cccc(Cc2ccccc2C(F)(F)F)c1,[Pd],CCO,,NN,O,test
US20060014797A1,CS(=O)(=O)Cl.OCCc1cc2ccccc2s1>>CS(=O)(=O)OCCc1cc2ccccc2s1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120015988A1,CC(C)(C(=N)NO)S(=O)(=O)c1ccc(Cl)cc1.Cn1nc(C(C)(C)C)cc1C(=O)Cl>>Cn1nc(C(C)(C)C)cc1-c1nc(C(C)(C)S(=O)(=O)c2ccc(Cl)cc2)no1,,c1ccncc1,,,,test
US07135469B2,C1CCNC1.COC(=O)CN1CCc2c(C(F)(F)F)nn(-c3ccc(OC)cc3)c2C1=O>>COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(CC(=O)N2CCCC2)CC3)cc1,,ClCCl,,C[Al](C)C,,test
US08748462B2,COCC1(c2cc(CO)ccc2-c2cc(OC)ncc2F)CCCC1.O=S(Cl)Cl>>COCC1(c2cc(CCl)ccc2-c2cc(OC)ncc2F)CCCC1,,ClCCl,,,,test
US20030096829A1,Brc1ccc(Br)nc1.CC(C)=O.CCCC[Sn](Cl)(CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)c1ccc(C(C)(C)O)nc1,,CCOCC,Cc1ccccc1,[Li]CCCC,,test
US05643931,COc1ccc(CON(Cc2ccc(C(=O)c3cccc(C(=O)c4ccc(CN(OCc5ccc(OC)cc5)C(N)=O)cc4)c3)cc2)C(N)=O)cc1>>NC(=O)N(O)Cc1ccc(C(=O)c2cccc(C(=O)c3ccc(CN(O)C(N)=O)cc3)c2)cc1,,O=C(O)C(F)(F)F,,COc1ccccc1,,test
US20120214802A1,CON(C)C(=O)[C@H](Cc1cc(F)cc(F)c1)N(Cc1ccccc1)Cc1ccccc1>>O=C[C@H](Cc1cc(F)cc(F)c1)N(Cc1ccccc1)Cc1ccccc1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110312936A1,O=C1NCCc2ncc(C(F)(F)F)cc21>>O=c1[nH]ccc2ncc(C(F)(F)F)cc12,,C1COCCO1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20070049632A1,CC(C)(C)OC(=O)NNc1ccccc1F.CC1(C)[C@H]2CC[C@]1(C)C(=O)C2C(=O)Cl>>CC(C)(C)OC(=O)NN(C(=O)C1C(=O)[C@@]2(C)CC[C@@H]1C2(C)C)c1ccccc1F,,ClCCl,,CCN(CC)CC,O,test
US20120122888A1,CN(C)C=CC=O.COC(=O)c1c(N)n[nH]c1N>>COC(=O)c1c(N)nn2cccnc12,,CCO,,CC(=O)O,,test
US06028116,CC1=C(CC(=O)Cl)c2cc(N(C)C)ccc2/C1=C\c1ccc(S(C)(=O)=O)cc1>>CC1=C(CCO)c2cc(N(C)C)ccc2/C1=C\c1ccc(S(C)(=O)=O)cc1,,C1CCOC1,,[BH4-].[Li+],,test
US20030078282A1,CC(C)Oc1cccc(Br)c1.CCN1CCC(=O)CC1>>CCN1CCC(O)(c2cccc(OC(C)C)c2)CC1,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US03960863,Cc1ccc2nc(C)c(CCCl)c(=O)n2c1.Cc1cccc(N2CCNCC2)c1>>Cc1cccc(N2CCN(CCc3c(C)nc4ccc(C)cn4c3=O)CC2)c1,,Cc1ccccc1,,,,test
US20140045936A1,C=C/C=C/c1ccccc1.COC(=O)C(=[N+]=[N-])c1ccccc1>>COC(=O)C1(c2ccccc2)CC1/C=C/c1ccccc1,,Cc1ccccc1,,,,test
US20020013466A1,CCOC(=O)C(C)Br.Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3ccc(O)cc3)c(Cl)cc2F)c1=O>>CCOC(=O)C(C)Oc1ccc(Oc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2Cl)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140371199A1,CC1(NC(=O)OC(C)(C)C)CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc(Cl)cc5)n4c3)cc2)CC1>>NC1CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc(Cl)cc5)n4c3)cc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050004122A1,CC(=O)[C@@H]1C[C@H](CC(=O)O)C1(C)C.CC(C)(C)O>>CC(=O)C1CC(CC(=O)OC(C)(C)C)C1(C)C,CN(C)C=O,CC(C)(C)O,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20120232056A1,CN1CCCC1.COC(=O)c1cc2nc(Cl)c(=O)[nH]c2cc1OC>>COC(=O)c1cc2nc(N3CCC[C@@H]3C)c(=O)[nH]c2cc1OC,,CS(C)=O,,CCN(C(C)C)C(C)C,Cl,test
US20100240708A1,CC(=O)[C@@H]1CCCC[C@H]1N(Cc1ccc(-c2ncco2)cc1F)S(=O)(=O)c1ccc(Cl)cc1.C[Mg]Br>>CC(C)(O)[C@@H]1CCCC[C@H]1N(Cc1ccc(-c2ncco2)cc1F)S(=O)(=O)c1ccc(Cl)cc1,,C1CCOC1,,Cc1ccccc1,,test
US20030216375A1,Cc1c(N)cccc1F.S=C(Cl)Cl>>Cc1c(F)cccc1N=C=S,,Cc1ccccc1,,CCN(CC)CC,,test
US04985419,CCNCC(C)N1c2ccccc2Sc2ccc(C#N)cc21.CI>>CCN(C)CC(C)N1c2ccccc2Sc2ccc(C#N)cc21,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20090099213A1,Clc1ncnc2[nH]ccc12.NC(c1ccc(Cl)cc1)C1CCNCC1>>NC(c1ccc(Cl)cc1)C1CCN(c2ncnc3[nH]ccc23)CC1,,CCCCO,,CCN(CC)CC,Cl,test
US20120244071A1,CC1=NC(CO)(CCc2ccc(OCCCC/C=C/I)cc2)CO1.Cl>>Cl.NC(CO)(CO)CCc1ccc(OCCCC/C=C/I)cc1,,CCO,,,,test
US20090018103A1,CC(C)(C)OC(=O)NC[C@@H](N)CC1CCCCC1.COCCCOC(c1ccccc1F)C1CCCN(c2c(OC)c(=O)c2=O)C1>>COCCCOC(c1ccccc1F)C1CCCN(c2c(N[C@H](CNC(=O)OC(C)(C)C)CC3CCCCC3)c(=O)c2=O)C1,,CC#N,,,,test
US20150353533A1,CC(C)(C)OC(=O)N[C@H]1CCc2cc(-c3nnn[nH]3)ccc2NC1=O>>N[C@H]1CCc2cc(-c3nnn[nH]3)ccc2NC1=O,,ClCCl,,Cl,,test
US20100144825A1,Cc1ccc(Cl)cc1C(CCN(C)C(=O)OC(C)(C)C)OCCN=[N+]=[N-]>>Cc1ccc(Cl)cc1C(CCN(C)C(=O)OC(C)(C)C)OCCN,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150329554A1,O=C(Nc1ccc(Cl)c(Cl)c1)C1=C(c2cccc(C(F)(F)F)n2)C2CCC1O2>>O=C(Nc1ccc(Cl)c(Cl)c1)[C@H]1[C@H]2CC[C@H](O2)[C@H]1c1cccc(C(F)(F)F)n1,[Pd],,,,,test
US20080076924A1,Nc1cccc2c1CCNC2.O=CC1CC1>>Nc1cccc2c1CCN(CC1CC1)C2,CC(=O)O,CN(C)C=O,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130087772A1,CC(C)(C)c1ccc(C(=O)Cl)cc1.NNC(=O)c1ccc(Br)cc1>>CC(C)(C)c1ccc(C(=O)NNC(=O)c2ccc(Br)cc2)cc1,,C1CCOC1,,c1ccncc1,,test
US20100267676A1,Nc1cc([C@H](CNC(=O)C(F)(F)F)CC(=O)[O-])ccc1Cl.O=C(Cl)c1ccccc1>>NC[C@H](CC(=O)O)c1ccc(Cl)c(NC(=O)c2ccccc2)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US08481731B2,CC(C)OC(=O)Cl.CN(c1cc(N2CCc3cc(S(C)(=O)=O)ccc32)ncn1)C1CCNCC1>>CC(C)OC(=O)N1CCC(N(C)c2cc(N3CCc4cc(S(C)(=O)=O)ccc43)ncn2)CC1,,Cc1ccccc1,ClCCl,CCN(CC)CC,,test
US20100137317A1,CC1(C)OC(c2ccc([N+](=O)[O-])cc2)=C(c2ccc(OCc3ccc4ccccc4n3)cc2)C1=O>>CC1(C)OC(c2ccc(N)cc2)=C(c2ccc(OCc3ccc4ccccc4n3)cc2)C1=O,[Fe],CCO,,CC(=O)O,,test
US20120101083A1,CC(C)Oc1ccc(-c2nnc(Br)s2)cc1Cl.Cc1c(B2OC(C)(C)C(C)(C)O2)ccc2c1CCN(C(=O)OC(C)(C)C)C2>>Cc1c(-c2nnc(-c3ccc(OC(C)C)c(Cl)c3)s2)ccc2c1CCN(C(=O)OC(C)(C)C)C2,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20050176743A1,CSc1ccc([N+](=O)[O-])cc1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1ccc([N+](=O)[O-])cc1,,ClCCl,,,,test
US20040176432A1,C[C@H]1C(=O)O[C@@]1(Cn1cncn1)c1cc(F)ccc1F.N>>C[C@@H](C(N)=O)[C@](O)(Cn1cncn1)c1cc(F)ccc1F,,N,,CN(C)c1ccccn1,,test
US20060223996A1,CN(CCOc1cc(NN)nc(N2CCOCC2)n1)C(=O)OC(C)(C)C.O=N[O-]>>CN(CCOc1cc(N=[N+]=[N-])nc(N2CCOCC2)n1)C(=O)OC(C)(C)C,,CC(=O)O,O,CCOC(C)=O,,test
US20150126525A1,N#Cc1ccc2[nH]cc(CCCC=O)c2c1.NC(=O)c1cc2cc(N3CCNCC3)ccc2o1>>N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc5oc(C(N)=O)cc5c4)CC3)c2c1,,CO,,[BH3-]C#N.[Na+],,test
US20040116490A1,CC(C)c1ccccc1NC(N)=S.CCI>>CCSC(=N)Nc1ccccc1C(C)C.I,,CCO,,,,test
US20130225554A1,CC(C)(C)OC(=O)NC(=O)NCCONC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1>>CC(C)(C)OC(=O)NC(=O)NCCONC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2O,[Pd],CO,,,,test
US05380850,COC(=O)C(C)(C)Cc1c(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc2n1S(=O)(=O)c1ccccc1.ClCc1ccccc1>>CC(C)(Cc1c(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc2n1Cc1ccccc1)C(=O)O,,O,,[Na],,test
US20120208817A1,BrCC1CCCCC1.CON(C)C(=O)c1ccccc1>>O=C(CC1CCCCC1)c1ccccc1,,C1CCOC1,,,,test
US05086070,CC(C)(C)NCCCOc1ccccc1C(O)c1cccc2[nH]ccc12.O=C(O)c1ccccc1>>CC(C)(C)NCCCOc1ccccc1C(OC(=O)c1ccccc1)c1cccc2[nH]ccc12,,CCOC(C)=O,,,,test
US20110275815A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.COc1cc(N)ccc1F>>COc1cc(NC2CCN(C(=O)OC(C)(C)C)CC2)ccc1F,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070219228A1,CCOCc1nc2c(N)nc3cc(Br)cnc3c2n1CC(C)(C)O.OCc1cccc(B(O)O)c1>>CCOCc1nc2c(N)nc3cc(-c4cccc(CO)c4)cnc3c2n1CC(C)(C)O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20040048915A1,CC=[N+]=CC.FC(F)(F)c1ccc2cc[nH]c2c1.[OH-]>>NC(=O)Cc1c[nH]c2cc(C(F)(F)F)ccc12,,ClCCl,,[Cl-].[Na+],,test
US04022901,O=[N+]([O-])c1ccc(-c2nc(-c3ccco3)no2)cc1>>Nc1ccc(-c2nc(-c3ccco3)no2)cc1,[Pd],,,Cl,O=C([O-])[O-].[K+].[K+],test
US20110319378A1,COC(=O)OC(=O)OC.COc1ccc(CN2C(=O)C(C)C[C@H](c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)c(OC)c1>>COC(=O)C1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(Cc2ccc(OC)cc2OC)C1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20150368269A1,CC(C)(C)OC(=O)Nc1cc2onc(N3C(=O)c4ccccc4C3=O)c2cc1N>>Nc1cc2onc(N3C(=O)c4ccccc4C3=O)c2cc1N,,C1COCCO1,,Cl,ClCCl,test
US20160221972A1,CC1=NCCOc2ccc(Br)cc21>>CC1NCCOc2ccc(Br)cc21,,CO,,CC(=O)[O-].[Na+],,test
US20080051458A1,CC(C)C(OC(=O)/C=C/c1ccccc1)OC(=O)NC1(C(=O)O)CC1>>CC(C)C(OC(=O)CCc1ccccc1)OC(=O)NC1(C(=O)O)CC1,[Pd],CCO,,CCOC(C)=O,,test
US05190934,CCOC(OCC)P(=O)(CC1CCCCC1)OCC>>OP(O)CC1CCCCC1,,O,,Cl,,test
US20110152290A1,COC(=O)C1(NC(=O)c2ccc(OC)c([N+](=O)[O-])c2)Cc2ccccc2C1>>COC(=O)C1(NC(=O)c2ccc(OC)c(N)c2)Cc2ccccc2C1,[Pd],CO,,,,test
US20090306043A1,CC(O)C1CN(Cc2ccccc2)CC1c1ccc(C#N)cc1.N#Cc1ccc(Cl)nc1>>CC(Oc1ccc(C#N)cn1)C1CN(Cc2ccccc2)CC1c1ccc(C#N)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20080255083A1,CC(C)(C)OC(=O)N1CCc2ccc(CCn3ncc(OCc4ccccc4)cc3=O)cc2C1>>O=c1cc(OCc2ccccc2)cnn1CCc1ccc2c(c1)CNCC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070167631A1,O=C1CCCC(=O)C1C(=O)c1ccc(C(F)(F)F)c(Cl)n1.c1cn[nH]c1>>O=C1CCCC(=O)C1C(=O)c1ccc(C(F)(F)F)c(-n2cccn2)n1,,CN1CCCC1=O,,O,[H-].[Na+],test
US20070021424A1,CCOC(=O)COC(=O)Oc1ccccc1.NCCOc1ccc(Cl)cc1>>CCOC(=O)COC(=O)NCCOc1ccc(Cl)cc1,,Cc1ccccc1,,,,test
US06756373B1,CCCCOc1ncc(C(C)=O)cc1-c1nc2c(CC)n(C3CCN(C(=O)OC(C)(C)C)CC3)nc2c(=O)[nH]1>>CCCCOc1ncc(C(C)=O)cc1-c1nc2c(CC)n(C3CCNCC3)nc2c(=O)[nH]1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040132727A1,CC(C)(C)c1ccc(CN2CCC(N)C2)cc1.COc1cc2ncnc(Oc3ccc(N)c([N+](=O)[O-])c3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2ncnc(Oc3ccc(NC(=O)NC4CCN(Cc5ccc(C(C)(C)C)cc5)C4)c([N+](=O)[O-])c3)c2cc1OC,,CCN(CC)CC,ClC(Cl)Cl,O=C([O-])O.[Na+],,test
US20140349991A1,COCOc1ccc2c(=O)c(C)c(N3CCN(C(C)=O)CC3)oc2c1C.Cl>>CC(=O)N1CCN(c2oc3c(C)c(O)ccc3c(=O)c2C)CC1.Cl,,C1COCCO1,,,,test
US20120245144A1,CI.Cc1nc(-c2cn3c(n2)-c2cc(Br)c(O)cc2OCC3)n(C(C)C)n1>>COc1cc2c(cc1Br)-c1nc(-c3nc(C)nn3C(C)C)cn1CCO2,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030013715A1,C[C@@H]1CC[C@@H](NC(=O)c2cnc3c(C(F)(F)F)cccc3c2Cl)CC1.O=S(Cl)Cl>>C[C@H]1CC[C@H](N)CC1.Cl,,CCN(CC)CC,,,,test
US20040006081A1,CCN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)C1CCNCC1.O=C(CCCl)c1ccc(F)cc1>>CCN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)C1CCN(CCC(=O)c2ccc(F)cc2)CC1.Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05854234,COC1=NCCC(C(C)(C)C)CC1.[Cl-].[NH4+]>>CC(C)(C)C1CCNC(=N)CC1.Cl,,CCO,,,,test
US20070203127A1,COc1ccc2nccc(OS(=O)(=O)C(F)(F)F)c2n1.OC1CCNC1>>COc1ccc2nccc(N3CCC(O)C3)c2n1,,CN(C)C=O,O,CCN(CC)CC,,test
US20110105463A1,CO.O=Cc1ccc(Br)cc1F>>COc1cc(Br)ccc1C=O,,CO,,C[O-].[Na+],,test
US20130344030A1,C=C[C@](C)(COC(F)(F)F)C(=O)OC>>C=C[C@](C)(COC(F)(F)F)C(=O)O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20120190677A1,CC(C)(C)c1ccc(-c2cncc(C3CC(C)(C)c4cc(C(=O)O)ccc4N3)c2)cc1.CS(N)(=O)=O>>CC(C)(C)c1ccc(-c2cncc(C3CC(C)(C)c4cc(C(=O)NS(C)(=O)=O)ccc4N3)c2)cc1,CN(C)c1ccncc1,ClCCl,,,,test
US20080287421A1,COC1CC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Br)ccc12.[NH4+].[OH-]>>CO[C@H]1C/C(=N/O)C[C@@H](c2cccc(Cl)c2)[C@]12C(=O)Nc1cc(Br)ccc12,,CCO,,Cl,[Na+].[OH-],test
US20060235037A1,CN(CCN1CCC(=O)CC1)C(=O)OC(C)(C)C.O=S(=O)(Nc1ccccc1)C(F)(F)F>>CN(CCN1CC=C(OS(=O)(=O)C(F)(F)F)CC1)C(=O)OC(C)(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20100222352A1,CC(C)=CCBr.CCOC(=O)c1coc(Nc2ccc(C)c(O)c2)n1>>CCOC(=O)c1coc(Nc2ccc(C)c(OCC=C(C)C)c2)n1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20060172999A1,CC(C)(C)OC(=O)N1CCC2(CC1)OCCC2O.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.OC1CCOC12CCNCC2,,ClCCl,,,,test
US20070043081A1,Cc1cc(N)cc(C)n1.O=C=NCCCl>>Cc1cc(NC(=O)NCCCl)cc(C)n1,,C1CCOC1,,,,test
US04775675,CC(C)(S)[C@@H](N)C(=O)O.CSc1ccc(C=O)cc1>>CSc1ccc(C2N[C@@H](C(=O)O)C(C)(C)S2)cc1,,CO,,,,test
US20100120763A1,COc1cc(F)cc(F)c1[N+](=O)[O-].Cc1c[nH]cn1>>COc1cc(F)cc(-n2cnc(C)c2)c1[N+](=O)[O-],,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050176745A1,Brc1coc2ccccc12.CCCC[Sn](Cl)(CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)c1coc2ccccc12,,CCOCC,,[Li]CCCC,,test
US20120184587A1,O=C(O)c1ccc(OCc2ccccc2)c(C(F)(F)F)c1.O=S(Cl)Cl>>O=C(Cl)c1ccc(OCc2ccccc2)c(C(F)(F)F)c1,,CN(C)C=O,,Cc1ccccc1,,test
US05622954,CC(=CCc1c(C)nc(N)nc1Cl)c1cc(Cl)ccc1Cl.[N-]=[N+]=[N-]>>CC(=CCc1c(C)nc(N)n2nnnc12)c1cc(Cl)ccc1Cl,,CS(C)=O,,[Cl-].[NH4+],,test
US20150126721A1,BrCc1ccccc1.CC1(C)O[C@@H]2[C@@H](O)[C@@H]([C@H]3COC(C)(C)O3)O[C@@H]2O1>>CC1(C)OCC(C2OC3OC(C)(C)OC3C2OCc2ccccc2)O1,,C1CCOC1,,[H-].[Na+],,test
US20150065482A1,Cc1cc(Cl)c(CO)cn1>>Cc1cc(Cl)c(C=O)cn1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05824652,CI.COC(=O)C1(C)Oc2ccccc2NC1=O>>COC(=O)[C@@]1(C)Oc2ccccc2N(C)C1=O,,Cc1ccccc1,,[H-].[Na+],,test
US05672712,CCOC(=O)c1sc(NC(=O)c2ccc(C#N)cc2)nc1C.CI>>CCOC(=O)c1sc(=NC(=O)c2ccc(C#N)cc2)n(C)c1C,,CN(C)C=O,Cl,[H-].[Na+],,test
US06596758B1,CCCCCC=CC=O.O=Cc1ccccc1O>>CCCCCC1Oc2ccccc2C=C1C=O,,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US04927819,Cc1ccc(S(=O)(=O)OCC2c3ccccc3C=Cc3ccccc32)cc1>>OC1=Cc2ccccc2C=Cc2ccccc21,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20110046169A1,COC(=O)c1cccc(-c2ccccc2)[n+]1[O-]>>O=C(O)c1cccc(-c2ccccc2)[n+]1[O-],,CO,,[Na+].[OH-],,test
US05286753,CCCN(CCC)C1CCc2cccc([Sn](C)(C)C)c2C1.COCC(=O)Cl>>CCCN(CCC)C1CCc2cccc(C(=O)COC)c2C1,,c1ccccc1,,O,,test
US20080200431A1,Cc1nc(N2CCC(C(=O)O)CC2)cnc1Cl.O=C(O)C(F)(F)F>>Cc1nc(N2CCC(C(=O)O)CC2)c[nH]c1=O,,O=C(O)C(F)(F)F,,CC(=O)[O-].[K+],,test
US20090258885A1,CC(C)(C)C(c1ccccc1)c1cc(OCc2ccc3cc(F)ccc3n2)ccc1C(=O)CBr.Nc1nccs1>>CC(C)(C)C(c1ccccc1)c1cc(OCc2ccc3cc(F)ccc3n2)ccc1-c1cn2ccsc2n1,,CCO,,,,test
US20090176778A1,N#CC1CCN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)C1.NO>>N=C(NO)C1CCN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)C1,,CCO,,,,test
US20040132727A1,COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.Cc1ccc(CO)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2ncnc(Oc3ccc(NC(=O)OCc4ccc(C)cc4)cc3)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20160152543A1,COC(=O)C(OC(C)(C)C)c1c(C)ccc(OCc2ccc(OC)cc2)c1-c1ccc(OC)cc1>>COC(=O)C(OC(C)(C)C)c1c(C)ccc(O)c1-c1ccc(OC)cc1,[Pd],CCOC(C)=O,,[H][H],,test
US20040097563A1,CC(C)(C)[Si](C)(C)Oc1ccccc1-c1cc(-c2cccc(N)c2)c(C#N)c(N)n1.O=C(O)CCN1CCCCC1>>CC(C)(C)[Si](C)(C)Oc1ccccc1-c1cc(-c2cccc(NC(=O)CCN3CCCCC3)c2)c(C#N)c(N)n1,,CC#N,ClCCl,O=C(Cl)C(=O)Cl,,test
US04486428,CCCCCCC(C)(C)c1cc(OCc2ccccc2)c2c(c1)OC(C)(C)CC2C#N.OCCO>>CCCCCCC(C)(C)c1cc(OCc2ccccc2)c2c(c1)OC(C)(C)CC2C(=O)O,,CCOCC,,Cl,[K+].[OH-],test
US20080113980A1,COc1ccc2c(c1)N(C(=O)OC(C)(C)C)CCC2>>COc1ccc2c(c1)NCCC2,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],test
US20100190770A1,C1COCCN1.O=[N+]([O-])c1ccc(Br)nc1>>O=[N+]([O-])c1ccc(N2CCOCC2)nc1,,ClCCl,,,,test
US06479265B1,O=C1C=CC(=O)O1.[NH3+]CCCCCC(=O)[O-]>>O=C(O)CCCCCN1C(=O)C=CC1=O,,CC(=O)O,,,,test
US20110201604A1,CNc1cc(C#N)ccc1[N+](=O)[O-]>>CNc1cc(C#N)ccc1N,[Pd],,,,,test
US20140135332A1,CS(=O)(=O)Cl.C[C@H](O)c1nc(-c2ccc(C(F)(F)F)cc2)co1>>C[C@H](OS(C)(=O)=O)c1nc(-c2ccc(C(F)(F)F)cc2)co1,,ClCCl,,CCN(CC)CC,O,test
US20070037260A1,CC(C)=O.C[C@](N)(CS)C(=O)O>>CC1(C)NC(C)(C(=O)O)CS1,,CO,,,,test
US03980788,CN.O=C1CCCN(Cc2ccccc2)C1>>CNC1CCCN(Cc2ccccc2)C1,O=[Pt],CCO,,[H][H],,test
US20050043388A1,NNC(=O)COc1ccc(C(=O)OCc2ccccc2)cc1>>NNC(=O)COc1ccc(C(=O)O)cc1,[Pd],CC(=O)O,,,,test
US20010027196A1,C=CC(=O)OC.Nc1ncc(I)c(-c2ccco2)n1>>COC(=O)/C=C/c1cnc(N)nc1-c1ccco1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090192156A1,O=C(COC1CCNCC1)N1CCCC1.O=C(O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F>>O=C(COC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccccc34)ccc2F)CC1)N1CCCC1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050064510A1,O=C(O)CC(=O)O.O=C1Nc2ccc(I)cc2C1=O>>O=C(O)c1cc(=O)[nH]c2ccc(I)cc12,,CC(=O)O,,,,test
US05420131,COC(=O)Cc1ccc(O)cc1.ClCc1ccc2ccccc2n1>>COC(=O)Cc1ccc(OCc2ccc3ccccc3n2)cc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20050043336A1,CC(=O)O.CCOC(C)=O.CN1CCC(Oc2cccc3ncnc(Nc4ccc(S(=O)(=O)c5nccs5)cc4)c23)CC1>>C#Cc1cc(N)ccc1C(=O)OC(C)(C)C,[Fe],CCOC(C)=O,O,,,test
US20130345192A1,CN(c1ncnc2c1cnn2COCC[Si](C)(C)C)[C@@H]1CCCNC1>>CN(c1ncnc2[nH]ncc12)[C@@H]1CCCNC1,,CCO,,Cl,,test
US05187094,CCCCCC(=O)O[C@H]1CCN(Cc2ccccc2)C1>>O[C@H]1CCN(Cc2ccccc2)C1,,CO,,,,test
US20140135318A1,CCCCN(CCCC)C(=O)c1nn(-c2ccc(C(=O)NS(=O)(=O)c3ccc4cccc(C(=O)OCC)c4c3)cc2C(=O)N2CCc3ccccc3C2)c(C)c1Cl>>CCCCN(CCCC)C(=O)c1nn(-c2ccc(C(=O)NS(=O)(=O)c3ccc4cccc(C(=O)O)c4c3)cc2C(=O)N2CCc3ccccc3C2)c(C)c1Cl,,C1CCOC1,CCO,[Li+].[OH-],,test
US05486466,Cc1c(O)cc(N)cc1C(=O)O.O=C1OC(=O)c2ccccc21>>Cc1c(O)cc(N2C(=O)c3ccccc3C2=O)cc1C(=O)O,,CN(C)C=O,,,,test
US20140128418A1,CCOC(=O)C(Cc1ccc([N+](=O)[O-])cc1)C(=O)c1ccccc1.NNc1ccccn1>>O=[N+]([O-])c1ccc(Cc2c(-c3ccccc3)nn(-c3ccccn3)c2O)cc1,,CCO,,,,test
US20050065160A1,COC(=O)CC1c2cccc(F)c2N=C(N2CCN(c3cccc(C)c3)CC2)N1c1cc(C(F)(F)F)ccc1OC>>COc1ccc(C(F)(F)F)cc1N1C(N2CCN(c3cccc(C)c3)CC2)=Nc2c(F)cccc2C1CC(=O)O,,C1COCCO1,,[Na+].[OH-],,test
US20080125431A1,O=C1OC2(CCCCC2)CN1Cc1ccc(I)cc1.OB(O)C1CN(Cc2ccccc2)CCO1>>O=C1OC2(CCCCC2)CN1Cc1ccc(-c2ccccc2CN2CCOCC2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,ClCCl,O=C([O-])[O-].[Na+].[Na+],,test
US03950339,Cc1cc(Cl)nc(SCC#N)n1.NCc1ccc2c(c1)OCO2>>Cc1cc(NCc2ccc3c(c2)OCO3)nc(SCC#N)n1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20110098276A1,CC[Mg]Br.N#Cc1ccc(OC(F)(F)F)cc1>>NC1(c2ccc(OC(F)(F)F)cc2)CC1,CC(C)O[Ti](OC(C)C)(OC(C)C)OC(C)C,CCOCC,,Cl,[Na+].[OH-],test
US20040147739A1,CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(OCC#N)ccc3N2)c(O)c2ccccc21>>CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(OCCN)ccc3N2)c(O)c2ccccc21,[Pd],CC(=O)O,,Cl,,test
US20110319403A1,CCC1CNc2ccc(-c3ccc(OCC(C)(C)C(=O)OC)nc3)cc2O1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCC1CN(C(=O)Cl)c2ccc(-c3ccc(OCC(C)(C)C(=O)OC)nc3)cc2O1,,ClCCl,,c1ccncc1,,test
US04775675,CC(C)(S)[C@@H](N)C(=O)O.O=Cc1ccc2c(c1)CCC2>>CC1(C)SC(c2ccc3c(c2)CCC3)N[C@H]1C(=O)O,,CO,,,,test
US20030109517A1,CCOC(=O)N=NC(=O)OCC.CCOC(C)=O.O=C1c2ccccc2C(=O)N1O.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>O=C(NCCON1C(=O)c2ccccc2C1=O)OCc1ccccc1,,CCOC(C)=O,,C1CCOC1,,test
US04826847,CC(C)=C1C(=O)Nc2ccc(O)cc21>>CC(C)C1C(=O)Nc2ccc(O)cc21,[Pd],C1CCOC1,,CCO,[H][H],test
US05527827,C[Si](C)(C)CCS.O=c1cc(-c2ccoc2)c2ccc(Br)cc2o1>>C[Si](C)(C)CCSc1ccc2c(-c3ccoc3)cc(=O)oc2c1,,CN1CCCC1=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US06100275,CN1C2CCC1CC(O)(c1ccccc1)C2.O=C(O)CC(=O)O>>CN1C2C=C(c3ccccc3)CC1CC2.O=C(O)CC(=O)O,,CCO,,CC(=O)O,Cl,test
US05576321,FC(F)(F)c1ccc(OC2(c3ccccc3)CCNCC2)cc1.O=C(O)C(=O)O.c1cc(OC[C@@H]2CO2)c2cc[nH]c2c1>>O=C(O)C(=O)O.O[C@H](COc1cccc2[nH]ccc12)CN1CCC(Oc2ccc(C(F)(F)F)cc2)(c2ccccc2)CC1,,CCOC(C)=O,,CO,,test
US20110076292A1,CC(C)n1ncnc1-c1c[nH]c(-c2ccc(OCc3ccccc3)cc2F)n1.O=C1OCCO1>>CC(C)n1ncnc1-c1cn(CCO)c(-c2ccc(OCc3ccccc3)cc2F)n1,,Cc1ccccc1,,,,test
US06608212B1,O=CCc1ccccc1.O=P(Cl)(Oc1ccccc1)Oc1ccccc1>>O=P(OC=Cc1ccccc1)(Oc1ccccc1)Oc1ccccc1,,CCOCC,ClCCl,C1CCC2=NCCCN2CC1,O,test
US20150126495A1,CC(C)(C)OC(=O)Nc1ccc(B(O)O)cc1.COC(=O)c1cc(Br)cn1C>>COC(=O)c1cc(-c2ccc(NC(=O)OC(C)(C)C)cc2)cn1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[K+].[K+],test
US20150018363A1,Cc1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cn12.OCc1ccc(Cl)cn1>>Cc1c(C2CC2)nc2ccc(-n3ccc(OCc4ccc(Cl)cn4)cc3=O)cn12,,C1CCOC1,CCOC(C)=O,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US06054457,CC(=O)OC(C)=O.CN1CCN(C(=O)CCCCCOc2ccccc2N(C)C(=O)c2ccc(NC(=O)c3ccccc3OCCCN)cc2)CC1>>CC(=O)NCCCOc1ccccc1C(=O)Nc1ccc(C(=O)N(C)c2ccccc2OCCCCCC(=O)N2CCN(C)CC2)cc1,,ClCCl,,CCN(CC)CC,,test
US20070010671A1,CN(C)c1nc(N[C@H]2CC[C@@H](NC(=O)OC(C)(C)C)CC2)nc2ccccc12>>CN(C)c1nc(N[C@@H]2CC[C@H](N)CC2)nc2ccccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090098218A1,C#CC(C)(C)O.CC1(C)OB(c2ccc(Br)cc2)OC1(C)C>>CC(C)(O)C#Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,CCN(CC)CC,,test
US20040024010A1,CC(C)c1cc(C=O)cc(C(C)C)c1O.OCCN1CCOCC1>>CC(C)c1cc(C=O)cc(C(C)C)c1OCCN1CCOCC1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120295915A1,Cc1cnc(NC[C@@H]2CCNC2)c([N+](=O)[O-])c1.O=C(Cl)C1CC1>>Cc1cnc(NC[C@@H]2CCN(C(=O)C3CC3)C2)c([N+](=O)[O-])c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090082261A1,COC(=O)[C@H]1C[C@H](O)CN1C(=O)OCc1ccccc1.O=C(n1ccnc1)n1ccnc1.c1ccc2c(c1)CCNC2>>COC(=O)[C@H]1C[C@H](OC(=O)N2CCc3ccccc3C2)CN1C(=O)OCc1ccccc1,,ClCCl,,,,test
US05750705,CO.N#Cc1cnn(-c2nc(F)c(C(F)(F)F)cc2Cl)c1N>>COc1nc(-n2ncc(C#N)c2N)c(Cl)cc1C(F)(F)F,,COC(C)(C)C,,Cl,[H-].[Na+],test
US20080227792A1,C[Si](C)(C)CCOc1ccc(NNC2=NC3(CCCC3)CS2)cn1>>Oc1ccc(NC2=NC3(CCCC3)CS2)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06057313,CS(=O)(=O)O.O=c1[nH]c2cc([N+](=O)[O-])c3c(c2[nH]c1=O)CCN(Cc1ccc(C(F)(F)F)cc1)C3>>CS(=O)(=O)O.O=c1[nH]c2cc([N+](=O)[O-])c3c(c2[nH]c1=O)CCN(Cc1ccc(C(F)(F)F)cc1)C3,,CN(C)C=O,,,,test
US04399145,CC(CCCO)(C(N)=O)N1C(=O)c2ccccc2S1(=O)=O>>CC1(N2C(=O)c3ccccc3S2(=O)=O)CCCNC1=O,,Cc1ccccc1C,,O,,test
US20110288090A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4ccnc(Cl)c4cc3-c3ccccc3)cc2)CCC1.Cl.O>>[Cl-].[NH3+]C1(c2ccc(-c3nc4cc[nH]c(=O)c4cc3-c3ccccc3)cc2)CCC1,,CCOC(C)=O,,C1COCCO1,,test
US20130005705A1,CC(C)=O.COC(=O)CC#N>>COC(=O)C(C#N)=C(C)C,,Cc1ccccc1,,CC(=O)O,O,test
US05747499,COC(=O)[C@H](CCc1nnnn1CC(=C=O)OC)NC(=O)OCc1ccccc1>>COC(=O)CCn1nnnc1CC[C@H](N)C(=O)OC,[Pd],,,CCOC(C)=O,,test
US20090221645A1,COC(=O)c1cccc2c(OC)cccc12>>COc1cccc2c(C(=O)O)cccc12,,CO,,[Na+].[OH-],,test
US20070054896A1,O=[N+]([O-])c1ccc(F)cc1.OC1CCCN(Cc2ccccc2)C1>>O=[N+]([O-])c1ccc(OC2CCCN(Cc3ccccc3)C2)cc1,,CN(C)C=O,O,[H-].[Na+],,test
US06498161B1,CCCN(c1ncccn1)C1CCN(C[C@H]2CN([C@@H]3CCCCC3CC(=O)OCc3ccccc3)C[C@@H]2c2cccc(F)c2)CC1>>CCCN(c1ncccn1)C1CCN(C[C@H]2CN([C@@H]3CCCCC3CC(=O)O)C[C@@H]2c2cccc(F)c2)CC1,[Pd],CO,,[H][H],,test
US20050075327A1,CC(=O)N1C[C@H](NC(=O)[C@H](C)OC(=O)Oc2ccc([N+](=O)[O-])cc2)C(=O)N(C)c2ccccc21.NCc1cc(F)cc(F)c1F>>CC(=O)N1C[C@H](NC(=O)[C@H](C)OC(=O)NCc2cc(F)cc(F)c2F)C(=O)N(C)c2ccccc21,,C1COCCO1,,,,test
US20130059845A1,CCOC(=O)c1ccc(-n2cnnc2-c2c(-c3cc(Cl)ccc3Cl)nc3ccccn23)cc1>>O=C(O)c1ccc(-n2cnnc2-c2c(-c3cc(Cl)ccc3Cl)nc3ccccn23)cc1,,C1CCOC1,CO,[Li+].[OH-],,test
US20140005213A1,CCBr.Cc1ccc2ccc(O)cc2n1>>CCOc1ccc2ccc(C)nc2c1,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040142935A1,CCN.Nc1ccc2[nH]cc(C3CN4CCC3CC4)c2c1>>Cc1nc2c(ccc3[nH]cc(C4CN5CCC4CC5)c32)[nH]1,O=[Mn]=O,CN(C)C=O,,,,test
US20050222410A1,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc(N2CCCC2)s1>>Nc1ccccc1NC(=O)c1ccc(N2CCCC2)s1,,C1COCCO1,,Cl,,test
US20080281105A1,Cc1cc(C=O)c(C)n1-c1ccccc1.Cc1ccc2ccc(Cl)cc2[n+]1C.O=S(=O)([O-])C(F)(F)F>>Cc1cc(/C=C/c2ccc3ccc(Cl)cc3[n+]2C)c(C)n1-c1ccccc1.O=S(=O)([O-])C(F)(F)F,C1CCNCC1,CO,,,,test
US20070167413A1,COc1cc(N2CCNCC2)nc(OC)n1.NS(=O)(=O)c1cccc(-c2nc(C(F)(F)F)nc(Cl)c2-c2ccccc2)c1>>COc1cc(N2CCN(c3nc(C(F)(F)F)nc(-c4cccc(S(N)(=O)=O)c4)c3-c3ccccc3)CC2)nc(OC)n1,,c1ccncc1,,,,test
US20060183756A1,CC(C)(N)CO.Cc1sc(S(=O)(=O)Cl)cc1[N+](=O)[O-]>>Cc1sc(S(=O)(=O)NC(C)(C)CO)cc1[N+](=O)[O-],,C1COCCO1,,CCN(CC)CC,,test
US20080085895A1,CC(C)(C)OC(=O)NCCC[C@H]1COCc2nc3cnc4ccccc4c3n21.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)OC(=O)NCCC[C@H]1COCc2nc3c[n+]([O-])c4ccccc4c3n21,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20070072925A1,Brc1cccc(C2OCCO2)c1.C#C[Si](C)(C)C>>C[Si](C)(C)C#Cc1cccc(C2OCCO2)c1,I[Cu]I,O,,CCN(CC)CC,CN(C)C=O,test
US20120214767A1,N.O=C1CCC(c2ccc3c(c2)CCc2c-3noc2-c2noc(-c3ccccc3)c2C(F)(F)F)C1.[C-]#N>>N#CC1(N)CCC(c2ccc3c(c2)CCc2c-3noc2-c2noc(-c3ccccc3)c2C(F)(F)F)C1,,CO,ClCCl,[Cl-].[NH4+],,test
US20130225524A1,COC(=O)c1cc(Nc2c(C(N)=O)cnc3cc(-c4c(C)n[nH]c4C)ccc23)cc(C(=O)OC)c1>>Cc1n[nH]c(C)c1-c1ccc2c(Nc3cc(C(=O)O)cc(C(=O)O)c3)c(C(N)=O)cnc2c1,,CO,,[Na+].[OH-],,test
US20120289551A1,CC(O)(Cc1ccnc(N)c1)c1ccccc1.O=C=NC(=O)c1ccccc1>>CC(O)(Cc1ccnc(NC(N)=O)c1)c1ccccc1,,ClCCl,,CCO,O=C([O-])[O-].[K+].[K+],test
US20100298301A1,CNCc1ccccc1.NC(=O)c1nc(-c2c(F)cccc2F)oc1-c1ccc(OCCCl)cc1>>CNCCOc1ccc(-c2oc(-c3c(F)cccc3F)nc2C(N)=O)cc1,[Pd],CO,,,,test
US20160024060A1,COCc1ccc(C(C)=O)c2sc(C(=O)Nc3ccc4c(CO)cccc4n3)c(C)c12.O=C1CCC(=O)O1>>COCc1ccc(C(C)=O)c2sc(C(=O)Nc3ccc4c(COC(=O)CCC(=O)O)cccc4n3)c(C)c12,CN(C)c1ccncc1,CN(C)C=O,,CCN(CC)CC,,test
US20160016951A1,CSc1ccc2cncc(-c3ccc(-c4cnn(C)c4)cc3)c2c1.O>>Cn1cc(-c2ccc(-c3cncc4ccc(S(C)=O)cc34)cc2)cn1,,O,,CO,,test
US05556939,COc1ccc(CSC(C)(C)C(=O)NCCN(CCN)CCNC(=O)C(C)(C)SCc2ccc(OC)cc2)cc1.S=C(Cl)Cl>>COc1ccc(CSC(C)(C)C(=O)NCCN(CCN=C=S)CCNC(=O)C(C)(C)SCc2ccc(OC)cc2)cc1,,ClCCl,,,,test
US20160168090A1,O=C(NCC1(O)CCCC(F)(F)C1)c1c[nH]c2cccc(Cl)c12.OCCN1CCCCC1>>O=C(NCC1(O)CCCC(F)(F)C1)c1cn(CCN2CCCCC2)c2cccc(Cl)c12,,Cc1ccccc1,,CCCCP(=CC#N)(CCCC)CCCC,,test
US20090170829A1,CC(C)(C)OC(=O)N1CCC(NC2CCc3cc(OC4CCN(c5ccc(C(F)(F)F)cc5)CC4)ccc32)CC1>>FC(F)(F)c1ccc(N2CCC(Oc3ccc4c(c3)CCC4NC3CCNCC3)CC2)cc1,,C1COCCO1,,Cl,,test
US20070208054A1,CC[Mg]Cl.CON(C)C(=O)Cc1ccc(Br)cc1>>CCC(=O)Cc1ccc(Br)cc1,,C1CCOC1,,,,test
US20100256363A1,C=CC[C@]1(c2cccs2)CCN([C@@H](C)c2ccc(Br)cc2)C(=O)O1.OB(O)c1ccc(F)cc1>>C=CC[C@]1(c2cccs2)CCN([C@@H](C)c2ccc(-c3ccc(F)cc3)cc2)C(=O)O1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05475042,CC(C)(C)c1cc(C(C)(C)C)c2op(Cl)oc3c(C(C)(C)C)cc(C(C)(C)C)cc3c2c1.O>>CC(C)(C)c1cc2c(c(C(C)(C)C)c1)O[PH](=O)Oc1c-2cc(C(C)(C)C)cc1C(C)(C)C,,Cc1ccccc1,,CCN(CC)CC,,test
US20140018373A1,CNc1ccc(C(F)(F)F)cc1[N+](=O)[O-].O=C1CCC(=O)N1Cl>>CNc1c(Cl)cc(C(F)(F)F)cc1[N+](=O)[O-],,O,,CN(C)C=O,,test
US20130150401A1,CC(C)(F)CN1CCC(C2Cc3cc(C4=CCN(S(C)(=O)=O)CC4)ncc3O2)CC1>>CC(C)(F)CN1CCC(C2Cc3cc(C4CCN(S(C)(=O)=O)CC4)ncc3O2)CC1,[Pd],CO,,,,test
US20140088101A1,CCCC[Sn](CCCC)(CCCC)c1cccnc1.COC(=O)c1nc(Br)c2c(cc(-c3ccc(C(F)(F)F)cc3)c(=O)n2Cc2ccccc2)c1O>>COC(=O)c1nc(-c2cccnc2)c2c(cc(-c3ccc(C(F)(F)F)cc3)c(=O)n2Cc2ccccc2)c1O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,O,CCOC(C)=O,Cl,test
US20070027178A1,Cc1c(NN)cccc1C(F)(F)F.Cl.O=C1CCNCC1>>Cc1c(C(F)(F)F)ccc2c3c([nH]c12)CCNC3.Cl,,CC(C)O,,O,,test
US03976633,CC(=O)Cl.N#Cc1ccc(C(F)(F)F)cc1N=NNc1cc(C(F)(F)F)ccc1C#N>>CC(=O)N(N=Nc1cc(C(F)(F)F)ccc1C#N)c1cc(C(F)(F)F)ccc1C#N,,CCOCC,,[H-].[Na+],,test
US20070167433A1,C=CC#N.COCCCN1CCOc2ccc(COC3CN(S(=O)(=O)c4ccc(C)cc4)CC(O)C3c3ccc(OC4CCN(c5cccc(F)c5)C4)cc3)cc21>>COCCCN1CCOc2ccc(COC3CN(S(=O)(=O)c4ccc(C)cc4)CC(OCCC#N)C3c3ccc(OC4CCN(c5cccc(F)c5)C4)cc3)cc21,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20020028834A1,CC(C)(C)OC(=O)N1CCC(CI)CC1.Cc1cc2onc(C)c2cc1C>>Cc1cc2onc(CCC3CCN(C(=O)OC(C)(C)C)CC3)c2cc1C,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20150191478A1,CCOC(OCC)c1cc2cncc(C#CC3CC3)c2o1>>O=Cc1cc2cncc(C#CC3CC3)c2o1,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20150291595A1,BrB(Br)Br.COc1ccc(NC(=O)c2c(N)ncnc2Cl)cc1F>>Nc1ncnc(Br)c1C(=O)Nc1ccc(O)c(F)c1,,ClCCl,,,,test
US20150322031A1,CC(C)(C)OC(=O)N1[C@H](c2ncc(-c3cnc4cc(-c5ccc6nc([C@@H]7C[C@H]8C[C@H]8N7C(=O)OC(C)(C)C)[nH]c6c5)ccc4n3)[nH]2)C[C@H]2C[C@H]21.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.c1ccc2nccnc2c1,,ClCCl,,,,test
US20110230462A1,CC(C)(C)OC(=O)N1CC(C#N)C1.CCI>>CCC1(C#N)CN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20150133428A1,CC(C)(C)N=C=O.CCOC(=O)c1c(I)nn2c1CNCC2>>CCOC(=O)c1c(I)nn2c1CN(C(=O)NC(C)(C)C)CC2,,C1CCOC1,,,,test
US04548932,CC(C)(C)OC(=O)CN1C(=O)[C@@H](N)COc2ccccc21.CCOC(=O)C(Br)CCCCCCCN1C(=O)c2ccccc2C1=O>>CCOC(=O)[C@@H](CCCCCCCN1C(=O)c2ccccc2C1=O)N[C@H]1COc2ccccc2N(CC(=O)OC(C)(C)C)C1=O,,CCN(CC)CC,,CC#N,,test
US20160052884A1,CCOC(=O)C(Cc1ccccc1)n1ccc(Br)cc1=O.N#Cc1ccc(Cl)cc1B(O)O>>CCOC(=O)C(Cc1ccccc1)n1ccc(-c2cc(Cl)ccc2C#N)cc1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20140329830A1,CCOC(=O)CCl.O=Cc1c(O)cccc1Cl>>CCOC(=O)c1cc2c(Cl)cccc2o1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130079412A1,COC(=O)CC(c1ccc(Cl)c(NC(=O)[C@H](c2ccc(Cl)cc2)[C@@H](C)C(F)(F)F)c1)C1CC1(F)F>>C[C@H](C(C(=O)Nc1cc(C(CC(=O)O)C2CC2(F)F)ccc1Cl)c1ccc(Cl)cc1)C(F)(F)F,,C1COCCO1,O,Cl,[Li+].[OH-],test
US20160176869A1,CC(C)(C)OC(=O)N1CN(c2nc(Cl)c3c(c2F)CNC3=O)[C@@H]2CCCC[C@@H]21.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1Cc2c(F)c(N3CN(C(=O)OC(C)(C)C)[C@H]4CCCC[C@H]43)nc(Cl)c2C1=O,CN(C)c1ccncc1,C1CCOC1,CC(C)O,O,,test
US04272541,BrCC1CC1.COc1ccc2c(c1O)[C@]13CCN[C@H](C2)[C@@H]1C[C@H](C)C(=O)C3>>COc1ccc2c(c1O)[C@]13CCN(CC4CC4)[C@H](C2)[C@@H]1C[C@H](C)C(=O)C3,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20060100219A1,N#Cc1ccc(CCN)cc1.O=C(Cl)OCc1ccccc1>>N#Cc1ccc(CCNC(=O)OCc2ccccc2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20120157425A1,CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(O)cc3)CC2)cc1.OC1CCOCC1>>CC(=O)N[C@@H](C)c1ccc(C2CCN(c3ccc(OC4CCOCC4)cc3)CC2)cc1,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05221665,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)O.CCOC(=O)CNC1CCCCCC1>>CCOC(=O)CN(C(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C1CCCCCC1,CN(C)c1ccncc1,ClCCl,,CCOC(C)=O,,test
US20110112074A1,Brc1cccc(Br)c1.CCI>>CCc1c(Br)cccc1Br,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20070179156A1,O=C(Nc1ccc[nH]c1=O)OCc1ccccc1.O=C1CCC(=O)N1I>>O=C(Nc1cc(I)c[nH]c1=O)OCc1ccccc1,,ClCCl,,,,test
US20060074071A1,CC(C)(C)OC(=O)N1CCC[C@H]1CNCc1cc2ccccc2s1.COc1cc(C(=O)Cl)cc2c1OC(C)(C)O2.O=C1CCC1>>COc1cc(C(=O)N(Cc2cc3ccccc3s2)C[C@@H]2CCCN2C2CCC2)cc2c1OC(C)(C)O2,,ClCCl,,CCN(CC)CC,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160272596A1,CC(=O)c1ccc(C(=O)N2C[C@H](NC(=O)OC(C)(C)C)C(=O)Nc3ccccc32)cc1.Cc1ccc2ccccc2c1CCl>>CC(=O)c1ccc(C(=O)N2C[C@H](NC(=O)OC(C)(C)C)C(=O)N(Cc3c(C)ccc4ccccc34)c3ccccc32)cc1,,CN(C)C=O,O,[I-].[Na+],O=C([O-])[O-].[Cs+].[Cs+],test
US06096780,CNC1CCCCC1.O=[N+]([O-])c1ccc(CBr)cc1>>CN(Cc1ccc([N+](=O)[O-])cc1)C1CCCCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05210092,CI.COC(=O)c1ccc(-c2c[nH]cc2C#N)cc1>>COC(=O)c1ccc(-c2cn(C)cc2C#N)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20080146614A1,CCOC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(OCCC(F)(F)F)cc2)c1CO.NC1CCCCC1>>O=C(NC1CCCCC1)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(OCCC(F)(F)F)cc2)c1CO,,CCOC(C)=O,Cc1ccccc1,C[Al](C)C,Cl,test
US20150291573A1,CS(=O)(=O)Cl.OC1COC(c2ccc(Cl)cc2)C1>>CS(=O)(=O)OC1COC(c2ccc(Cl)cc2)C1,,ClCCl,,,,test
US04479942,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O.O=C1c2ccccc2C(=O)N1CCCBr>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCCCN2C(=O)c3ccccc3C2=O)cc1)C(=O)O,,CS(C)=O,O,CC(C)(C)[O-].[K+],,test
US20110046371A1,COC(=O)C=CN1CCCCC1.O=C(Cl)C(F)F>>COC(=O)C(=CN1CCCCC1)C(=O)C(F)F,,Cc1ccccc1,,CCN(CC)CC,,test
US20090163488A1,COC(=O)c1cccc(O)c1.O=[N+]([O-])c1ccc(Cl)nc1>>COC(=O)c1cccc(Oc2ccc([N+](=O)[O-])cn2)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20160200714A1,C/C(N)=N\OC(=O)[C@H]1CC[C@@H](N(C)C(=O)OC(C)(C)C)C1>>Cc1noc([C@H]2CC[C@@H](N(C)C(=O)OC(C)(C)C)C2)n1,,CCO,,O,CC(=O)[O-].[Na+],test
US20020173490A1,C=Cc1sc(NC(=O)OC(C)(C)C)nc1C(=O)OCP(=O)(OCC)OCC>>CCOP(=O)(COC(=O)c1nc(NC(=O)OC(C)(C)C)sc1CC)OCC,[Pd],CO,,,,test
US20090306133A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CN)CC1.O=C(O)c1cc(Cl)ncc1Cl>>CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CNC(=O)c2cc(Cl)ncc2Cl)CC1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20130079365A1,CN1C(=O)CCc2cc(-c3cncc4c3CCCN4CCNC(=O)OC(C)(C)C)ccc21.Cl>>CN1C(=O)CCc2cc(-c3cncc4c3CCCN4CCN)ccc21.Cl,,CO,,C1COCCO1,,test
US20120058988A1,COC(=O)c1ccc(-c2nc(-c3ccc(OC)c(F)c3)cc(C(=O)OC)c2N=[N+]=[N-])cc1>>COC(=O)c1ccc2c(c1)[nH]c1c(C(=O)OC)cc(-c3ccc(OC)c(F)c3)nc12,,Clc1ccccc1Cl,,,,test
US20090227591A1,Fc1cc(F)c(CBr)c(F)c1.O=C(O)c1cncc(C2=C(c3cc(C(F)(F)F)ccc3O)CCC2)n1>>O=C(O)c1cncc(C2=C(c3cc(C(F)(F)F)ccc3OCc3c(F)cc(F)cc3F)CCC2)n1,,CO,,[I-].[K+],,test
US20120046267A1,CCOC(=O)c1cncc(Br)c1Br>>O=Cc1cncc(Br)c1Br,,ClCCl,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20130085164A1,CC(C)n1cc(I)ccc1=O.O=Cc1ccc(B(O)O)s1>>CC(C)n1cc(-c2ccc(C=O)s2)ccc1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20100292238A1,COc1ccc(C2=C(c3ccc(OCc4ccccc4)cc3)C(=O)C(C)(C)O2)cc1>>COc1ccc(C2=C(c3ccc(O)cc3)C(=O)C(C)(C)O2)cc1,[Pd],CO,,[H][H],,test
US20080096860A1,C[C@@H](O)[C@H]1COC(C)(C)O1.Fc1cccc(CSc2nc(Cl)cc(Cl)n2)c1F>>C[C@@H](Oc1cc(Cl)nc(SCc2cccc(F)c2F)n1)[C@H]1COC(C)(C)O1,,C1CCOC1,,[H-].[Na+],,test
US06022307,Nc1ccc(-c2ccc(N)cc2)cc1.O=S(=O)(O)O>>Nc1ccc2c(c1)S(=O)(=O)c1cc(N)ccc1-2,,O=S(=O)(O)O,,,,test
US20110218192A1,C[Si](C)(C)N=C=N[Si](C)(C)C.N#Cc1cccc(-c2ccc3c(c2)C(=O)CC2(CCOCC2)O3)c1>>N#C/N=C1/CC2(CCOCC2)Oc2ccc(-c3cccc(C#N)c3)cc21,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20100273755A1,CN(CCCN)C(=O)OC(C)(C)C.O=C(Cl)OCC1c2ccccc2-c2ccccc21>>CN(CCCNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC(C)(C)C,,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20030236412A1,CCOC(=O)c1cnn(-c2ccc([N+](=O)[O-])cc2)c1C(F)(F)F>>CCOC(=O)c1cnn(-c2ccc(N)cc2)c1C(F)(F)F,[Pd],CO,,O=C[O-].[NH4+],,test
US20150045560A1,CCCCC#Cc1ccc2c(NCCCCC)c(C#CCCCC)ccc2c1NCCCCC>>CCCCCn1c(CCCC)cc2ccc3c(ccc4cc(CCCC)n(CCCCC)c43)c21,,CS(C)=O,,[K+].[OH-],,test
US20130131017A1,CC(NC(=O)OC(C)(C)C)c1ccc2c(c1)B(O)OC2(C)C.Cl>>CC(N)c1ccc2c(c1)B(O)OC2(C)C.Cl,,CO,,O,,test
US06369063B1,CCOC(=O)CN1C=CN(C(=O)OCc2ccccc2)[C@@H](Cc2ccccc2)C1=O>>CCOC(=O)CN1C=CN[C@@H](Cc2ccccc2)C1=O,[Pd],CCO,,Cl,,test
US20120309754A1,C1CCNC1.CCOC(=O)c1cc2nc(Cl)cc(NC3CCOCC3)n2n1>>CCOC(=O)c1cc2nc(N3CCCC3)cc(NC3CCOCC3)n2n1,,CC(=O)N(C)C,,CCN(CC)CC,O,test
US05859009,CCC1(CC)COC2(CCC(=O)CC2)OC1>>CCC1(CC)COC2(CCC(O)CC2)OC1,,CCO,,[BH4-].[Na+],,test
US20120071505A1,CCCSCC(=O)OC.COC=O.COc1ccc(N)cc1>>CCCSC(=CNc1ccc(OC)cc1)C(=O)OC,,CCOCC,O,Cl,C[O-].[Na+],test
US04476307,COS(=O)(=O)OC.Cc1cc(Br)cc(Cl)c1O>>COc1c(C)cc(Br)cc1Cl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150353499A1,NO.O=C1CCCc2ccc(OCc3ccccc3)cc21>>ON=C1CCCc2ccc(OCc3ccccc3)cc21,,CO,O,Cl,CC(=O)[O-].[Na+],test
US20120196864A1,COc1cc(OCc2ccc(C(F)(F)F)cc2C(F)(F)F)ccc1/C=C1\SC(=O)NC1=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COc1cc(OCc2ccc(C(F)(F)F)cc2C(F)(F)F)ccc1/C=C1\SC(=O)NC1=S,,C1CCOC1,Cc1ccccc1,,,test
US04230713,CN1CC(=O)NC1=NC(=O)O.Cc1ccnc(N)c1>>Cc1ccnc(NC(=O)N=C2NC(=O)CN2C)c1,,CN(C)C=O,,,,test
US20100261679A1,CNC(=O)c1cc(Oc2ccc3nc(N)ncc3c2)ccn1.O=C(Cl)C1CCCCC1>>CNC(=O)c1cc(Oc2ccc3nc(NC(=O)C4CCCCC4)ncc3c2)ccn1,,CN1CCCC1=O,,,,test
US20100056502A1,CCOC(=O)CCn1c(=O)sc2ccc(F)cc21>>O=C(O)CCn1c(=O)sc2ccc(F)cc21,,Cl,,,,test
US05034391,COc1ccccc1N1CCN(CCCCN)CC1.Clc1cc(Cl)c(Cl)nn1>>COc1ccccc1N1CCN(CCCCNc2cc(Cl)nnc2Cl)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120157451A1,O=[N+]([O-])c1cnc2cc(-c3ccc(Cl)cc3)nn2c1>>Nc1cnc2cc(-c3ccc(Cl)cc3)nn2c1,[Pt],CCOC(C)=O,CO,,,test
US20120196864A1,CNC1=NC(=O)SC1.COc1cc(C=O)c(Cl)cc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F>>CNC1=NC(=O)S/C1=C\c1cc(OC)c(OCc2ccc(C(F)(F)F)cc2C(F)(F)F)cc1Cl,,CCO,,CC(C)(C)[O-].[K+],,test
US20020156081A1,Fc1cc(C(F)(F)F)ccc1C(=S)Nc1ccc(Br)cc1.NO>>ON=C(Nc1ccc(Br)cc1)c1ccc(C(F)(F)F)cc1F,,CCO,,Cl,O=C([O-])O.[Na+],test
US20080214495A1,C/C(=C\c1ccc(Cl)s1)S(=O)(=O)Cl.O=C(C1CCN(c2ccc(=O)[nH]n2)CC1)N1CCNCC1>>C/C(=C\c1ccc(Cl)s1)S(=O)(=O)N1CCN(C(=O)C2CCN(c3ccc(=O)[nH]n3)CC2)CC1,,CN(C)C=O,,Cl,,test
US20060100194A1,CN(C)C=C1CC(=O)Nc2cc(Cl)ccc2C1=O.N=C(N)Nc1ccc(C(=O)O)cc1>>O=C1Cc2cnc(Nc3ccc(C(=O)O)cc3)nc2-c2ccc(Cl)cc2N1,,CCO,CN(C)C=O,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20110021520A1,COC(=O)c1ccc(O)cn1.COCCO>>COCCOc1ccc(C(=O)OC)nc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050239841A1,COc1ccc([C@@]23CC[C@@H](N)C[C@@H]2N(C)CC3)cc1OC.COc1ncccc1N.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc([C@@]23CC[C@@H](NC(=O)Nc4cccnc4OC)C[C@@H]2N(C)CC3)cc1OC,,ClCCl,,CCN(CC)CC,,test
US20150065519A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.NC(=O)c1ccc(F)cc1C(F)(F)F>>NC(=S)c1ccc(F)cc1C(F)(F)F,,Cc1ccccc1,O,,,test
US20120059002A1,COc1cc(OC)c2c(=O)[nH]c(-c3cc(C)c(OCCN)c(C)c3)nc2c1.O=C(N=C=S)c1ccccc1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCNC(=S)NC(=O)c4ccccc4)c(C)c3)nc2c1,,CC(Cl)Cl,,,,test
US20070087994A1,CC(=O)OC[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)nc(I)nc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O.CCCC[Sn](C#N)(CCCC)CCCC>>CC(=O)OC[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)nc(C#N)nc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US06740662B1,CCn1c(=O)c(CCCC(=O)O)c(-c2cccc(Cl)c2)c2ccc(C)nc21.N>>CCn1c(=O)c(CCCC(N)=O)c(-c2cccc(Cl)c2)c2ccc(C)nc21,CN(C)C=O,C1CCOC1,,O=C(Cl)C(=O)Cl,,test
US20100113410A1,COc1c(C)cnc(Cn2nc(CC3COC(C)(C)O3)c3c(Cl)nc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nc32)c1C.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1c(C)cnc(Cn2nc(CCOS(=O)(=O)c3ccc(C)cc3)c3c(Cl)nc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nc32)c1C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20090163489A1,Cc1ccc(S(=O)(=O)Nc2ccc(Cl)nn2)cc1.NC(=O)CI>>Cc1ccc(S(=O)(=O)N=c2ccc(Cl)nn2CC(N)=O)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,,test
US20150119395A1,COc1ccc(COc2cc(OCc3ccc(OC)cc3)c(C(C)C)cc2-c2ccc(-c3cccnc3)n2-c2ccc(N3CCOCC3)cc2)cc1>>CC(C)c1cc(-c2ccc(-c3cccnc3)n2-c2ccc(N3CCOCC3)cc2)c(O)cc1O,,CCO,,Br,,test
US06350913B1,BrC1CCCC1.COc1ccc(O)cc1C=O>>COc1ccc(OC2CCCC2)cc1C=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US06350845B1,C1CCOC1.CCCCCCCCC(=O)Cl.CCN(CC)CC.Nc1ccc(O)cc1O>>CCCCCCCC.O=C(Nc1ccccc1)c1ccc(O)cc1O,,C1CCOC1,,O,,test
US20070049593A1,CC(C)(C)NS(=O)(=O)c1ccc2c(C3CCCCC3)c(Br)[nH]c2c1.Cc1ccc(B2OC(C)(C)C(C)(C)O2)c(N)c1>>Cc1ccc(-c2[nH]c3cc(S(=O)(=O)NC(C)(C)C)ccc3c2C2CCCCC2)c(N)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])O.[Na+],,test
US20140309227A1,Br[Mg]C1CC1.NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(Cn3cc(C=O)cn3)cc2n1>>NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(Cn3cc(C(O)C4CC4)cn3)cc2n1,,C1CCOC1,,,,test
US03932168,N#CCN.O=C(Cl)COc1ccc(Cl)cc1Cl>>N#CCNC(=O)COc1ccc(Cl)cc1Cl,,c1ccccc1,,CCN(CC)CC,Cl,test
US20070123534A1,Cc1c(OCCN2CCN(C)CC2)cn2ncnc(Oc3ccc([N+](=O)[O-])cc3F)c12>>Cc1c(OCCN2CCN(C)CC2)cn2ncnc(Oc3ccc(N)cc3F)c12,[Zn],C1CCOC1,CO,[Cl-].[NH4+],,test
US20080051416A1,Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC(C)(C)C)cc1C(=O)O.NCCCn1ccnc1>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC(C)(C)C)cc1C(=O)NCCCn1ccnc1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130289017A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Ic1c[nH]c2ncncc12>>CC(C)(C)OC(=O)n1cc(I)c2cncnc21,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20050277652A1,CN(C)CC1CCN(C(=O)Nc2cc(Oc3ccc(N)cc3)ccn2)CC1.O=C=NC(=O)Cc1ccc(F)cc1>>CN(C)CC1CCN(C(=O)Nc2cc(Oc3ccc(NC(=O)NC(=O)Cc4ccc(F)cc4)cc3)ccn2)CC1,,C1CCOC1,,,,test
US20100292210A1,COc1nc(Nc2ccc3c(n2)O[C@H](c2ccccc2)CN(C(=O)OC(C)(C)C)C3)ccc1-c1cnn(C)c1>>COc1nc(Nc2ccc3c(n2)O[C@H](c2ccccc2)CNC3)ccc1-c1cnn(C)c1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US03951952,CC(=O)Nc1ccc(C(N)=S)cc1.CI>>CSC(=N)c1ccc(NC(C)=O)cc1.I,,CC(C)=O,,,,test
US20100197630A1,CC(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)NCC4CCC(=O)CC4)cc3)oc12.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)NCC4CC=C(OS(=O)(=O)C(F)(F)F)CC4)cc3)oc12,,ClCCl,,Cc1cccc(C)n1,,test
US20070117847A1,CCCCOC(=O)N1CCC(c2ccnn2C)CC1.O=C(O)C(F)(F)F>>Cn1nccc1C1CCNCC1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US03931407,COC(=O)c1ccccc1N.O=C(CC1CCCCC1=O)c1ccccc1>>COC(=O)c1ccccc1-n1c(-c2ccccc2)cc2c1CCCC2,,O,,CC(=O)O,,test
US20100105655A1,COCC(=O)Cl.COc1cc(N2CCNCC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1>>COCC(=O)N1CCN(c2ccc(Nc3ncc(Cl)c(-c4cnc5ccccn45)n3)c(OC)c2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090264445A1,CC(C)C[C@@H](C(=O)O)N1CC(Oc2cccc(N3CCCC3)c2F)=CC1=O.CC1(C)OC[C@@H](Cn2ccc(N)n2)O1>>CC(C)C[C@@H](C(=O)Nc1ccn(C[C@@H]2COC(C)(C)O2)n1)N1CC(Oc2cccc(N3CCCC3)c2F)=CC1=O,,CN(C)C=O,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US20130190338A1,COC(=O)c1ccccc1CSc1ccc(C)cc1N.O=S(=O)(Cl)c1cc2ccccc2o1>>COC(=O)c1ccccc1CSc1ccc(C)cc1NS(=O)(=O)c1cc2ccccc2o1,,c1ccncc1,,,,test
US08338622B2,NC(CO)(CO)CO.O=C(O)CC[C@H]1CC[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)O1>>NC(CO)(CO)CO.O=C(O)CC[C@H]1CC[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)O1,,CO,O,,,test
US05552402,NNc1ccc(-n2cnnc2)cc1>>c1ccc2[nH]ccc2c1,,O=S(=O)(O)O,,O=C([O-])[O-].[K+].[K+],,test
US20160272617A1,COC(=O)c1ccc(-c2ccc(C[C@H](NC(=O)[C@@H]3CC[C@@H](CNC(=O)OC(C)(C)C)CC3)C(=O)O)cc2)c(C)c1.Nc1ccc2[nH]c(C(F)(F)F)nc2c1>>COC(=O)c1ccc(-c2ccc(C[C@H](NC(=O)[C@@H]3CC[C@@H](CNC(=O)OC(C)(C)C)CC3)C(=O)Nc3ccc4[nH]c(C(F)(F)F)nc4c3)cc2)c(C)c1,,CCOCC,CN(C)C=O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US05783605,CCN.O=C(Cl)Cc1ccccc1>>CCNC(=O)Cc1ccccc1,,c1ccccc1,,,,test
US20160235716A1,Cc1oncc1C(=O)Nc1ccc2c(c1)CC[C@]21NC(=O)N(CC(=O)N(Cc2ccccc2)C(C)C2CC2)C1=O.O=C1NC(=O)C2(CCc3[nH]c(=O)ccc32)N1>>COc1ccc(CN(C(=O)CN2C(=O)N[C@]3(CCc4ccccc43)C2=O)[C@@H](C)C2CC2)cn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06417194B1,BrCc1ccccc1.COc1ccc(C=O)c(O)c1OC>>COc1ccc(C=O)c(OCc2ccccc2)c1OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20060252811A1,ClCc1nccn1Cc1cc(Cl)cc(Cl)c1.Nc1cccc(O)c1>>Nc1cccc(OCc2nccn2Cc2cc(Cl)cc(Cl)c2)c1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20130317026A1,CCOC(=O)c1cc(-c2ccc(CN3CCOCC3)cc2)nc2c1c(Br)nn2C(C)C>>CC(C)n1nc(Br)c2c(C(=O)O)cc(-c3ccc(CN4CCOCC4)cc3)nc21,,CCO,CCO,[Na+].[OH-],,test
US20150073019A1,COC(OC)N(C)C.O=c1cc(-c2cccc(F)c2)[nH]n1-c1nc2ccccc2s1>>CN(C)C=C1C(=O)N(c2nc3ccccc3s2)N=C1c1cccc(F)c1,,C1CCOC1,,CCOCC,,test
US20120142732A1,C1CCNC1.CC(=O)Nc1cc(-c2cc(-c3ncn(COCC[Si](C)(C)C)n3)c(-c3cc(C=O)ccc3Cl)o2)c(C)cn1>>CC(=O)Nc1cc(-c2cc(-c3ncn(COCC[Si](C)(C)C)n3)c(-c3cc(CN4CCCC4)ccc3Cl)o2)c(C)cn1,,ClCCl,O,,,test
US03940407,BrCC1CO1.Oc1ccc(-c2csnn2)cc1>>c1cc(-c2csnn2)ccc1OCC1CO1,,O,,[Na+].[OH-],,test
US04937268,Nc1c(Cl)cc(C(=O)CBr)cc1Cl.c1ccc(CNCCCOCCOCCCOc2ccccc2)cc1>>Nc1c(Cl)cc(C(O)CN(CCCOCCOCCCOc2ccccc2)Cc2ccccc2)cc1Cl,,C1CCOC1,,,,test
US04318915,N=C(N)N.O=C(Br)C(Br)c1c(Cl)cccc1Cl>>N=C(N)NC(=O)C(Br)c1c(Cl)cccc1Cl,,CC(C)=O,O,[Na+].[OH-],,test
US20130324737A1,CSCCC(=O)Cl.Clc1nc(-c2cccnc2)sc1NC1CC1>>CSCCC(=O)N(c1sc(-c2cccnc2)nc1Cl)C1CC1,CN(C)c1ccncc1,CCOC(C)=O,,Cl,O=C([O-])O.[Na+],test
US20030109545A1,CSC1C(=O)Nc2ccc(C)c(Cl)c21.O=C1CCC(=O)N1Cl>>Cc1ccc2c(c1Cl)C(=O)C(=O)N2,,ClC(Cl)(Cl)Cl,,C1CCOC1,O,test
US20130102468A1,Cn1nc(C(=O)O)c(=O)n(-c2ccccc2)c1=O.O=C(Cl)C(=O)Cl>>Cn1nc(C(=O)Cl)c(=O)n(-c2ccccc2)c1=O,,ClCCl,,CN(C)C=O,,test
US05929085,O=C(O)CC(=O)O.O=[N+]([O-])c1ccc2c(c1)C=NCC2>>O=C(O)CC1NCCc2ccc([N+](=O)[O-])cc21,,CC(=O)O,CCO,,,test
US20100311966A1,CC(C)(C)OC(=O)OC(=O)[O-].CC[C@H]1[C@@H](N)CN1C(c1ccccc1)c1ccccc1>>CC[C@H]1[C@@H](NC(=O)OC(C)(C)C)CN1C(c1ccccc1)c1ccccc1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20120010190A1,Cn1cc(C(=O)CC(c2cccc(C(=O)O)c2)c2ccc(Cl)cc2F)ccc1=O.NCCO>>Cn1cc(C(=O)CC(c2cccc(C(=O)NCCO)c2)c2ccc(Cl)cc2F)ccc1=O,,C1CCOC1,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US20100168418A1,CCCCOC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)ccc3c(NC)cccc32)CC1.Cl>>CNc1cccc2c1ccc(=O)n2CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1.Cl,,C1COCCO1,,,,test
US20100303928A1,CCOC(=O)C(=O)C(C)C(CC)=NO>>CCOC(=O)c1onc(CC)c1C,,CCO,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US05789440,CCOC(=O)C(CCc1ccccc1)C(C)=O.O=C(c1ccccc1)c1ccccc1>>O=C1OC(c2ccccc2)(c2ccccc2)CC(O)=C1CCc1ccccc1,,C1CCOC1,O,[Li]CCCC,[H-].[Na+],test
US20130274244A1,Cc1cc(CO)nn1C(C)C.O=S(Cl)Cl>>Cc1cc(CCl)nn1C(C)C.Cl,,ClCCl,,,,test
US05739083,CSC(=CC(=O)c1c(Cl)cc(C(F)(F)F)cc1Cl)SC.NN>>CSc1cc(-c2c(Cl)cc(C(F)(F)F)cc2Cl)n[nH]1,,CCO,,O,,test
US20060258861A1,CC1(c2ccc([N+](=O)[O-])cc2)OCCO1>>CC1(C2CCC(N)CC2)OCCO1,,CO,,,,test
US06245761B1,CN.Fc1ccc(Br)cc1CBr>>CNCc1cc(Br)ccc1F,,CO,,,,test
US20080004327A1,CCOC(=O)c1cc2ccsc2[nH]1.O=C(Cl)c1ccc(Cl)cc1>>CCOC(=O)c1cc2cc(C(=O)c3ccc(Cl)cc3)sc2[nH]1,,CC(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100168080A1,CN.COC(=O)c1cc(Cl)c(OC)cc1OCCCN1CCC(O)(c2ccc(Cl)cc2)C(C)(C)C1>>CNC(=O)c1cc(Cl)c(OC)cc1OCCCN1CCC(O)(c2ccc(Cl)cc2)C(C)(C)C1,,CCO,,,,test
US20140296226A1,COc1cnc(C(N)=O)cn1.O=C(NC1=N[C@@]2(CCO1)c1cc(I)ccc1Oc1ncc(Br)cc12)c1ccccc1>>COc1cnc(C(=O)Nc2ccc3c(c2)[C@@]2(CCOC(N)=N2)c2cc(Br)cnc2O3)cn1,,C1CCOC1,CO,N,,test
US04021442,COS(=O)(=O)OC.Cc1ncc([N+](=O)[O-])[nH]1>>Cc1ncc([N+](=O)[O-])n1C,,CC(=O)O,,,,test
US20090069282A1,CCOC(=O)N1CCC(=O)C(Br)CC1.Sc1ccc(Br)cc1>>CCOC(=O)N1CCC(=O)C(Sc2ccc(Br)cc2)CC1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20140235628A1,CC(C)(C)OC(=O)CC(=O)OC(C)(C)C.N#Cc1ccc(F)c(Cl)c1F>>CC(C)(C)OC(=O)C(C(=O)OC(C)(C)C)c1ccc(C#N)c(F)c1Cl,,CN(C)C=O,,[H-].[Na+],,test
US06248772B1,COC(=O)c1cccc2c1ccn2C.Cl.N=C(N)N>>Cl.Cn1ccc2c(C(=O)NC(=N)N)cccc21,,CO,,C[O-].[Na+],,test
US20160176857A1,Cc1cc(C=O)cc(C)c1O.N#Cc1cccc(Nc2n[nH]c(N)c2C(N)=O)c1>>Cc1cc(CNc2[nH]nc(Nc3cccc(C#N)c3)c2C(N)=O)cc(C)c1O,C1CCNCC1,CCO,,O,[BH4-].[Na+],test
US20160096827A1,C=O.C[C@H](O)C(=O)N1CC[C@H](Oc2ccc(-c3ncnc(Nc4ccc(N5CCNCC5)cc4)n3)cc2C#N)[C@H](F)C1>>C[C@H](O)C(=O)N1CC[C@H](Oc2ccc(-c3ncnc(Nc4ccc(N5CCN(C)CC5)cc4)n3)cc2C#N)[C@H](F)C1,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05225409,CN1C(=O)COc2cc(CCCCBr)ccc21.CNCc1ccccc1>>CN(CCCCc1ccc2c(c1)OCC(=O)N2C)Cc1ccccc1,,C1COCCO1,,,,test
US20050282808A1,CI.CN(C)[C@@H]1CC[C@@H](C(=O)Nc2c(C(=O)Nc3ccc(Cl)cc3)oc3ccccc23)CC1>>C[N+](C)(C)C1CCC(C(=O)Nc2c(C(=O)Nc3ccc(Cl)cc3)oc3ccccc23)CC1.[I-],,ClCCl,,,,test
US05998436,Fc1nc(F)c(Cl)c(F)c1F.N>>Nc1c(F)c(F)nc(F)c1Cl,,O,,CC#N,,test
US20080269268A1,Cn1ccc2c(Nc3ccc(N)cc3F)ccnc21.Nc1nc(Cl)cc(-c2ccncc2)n1>>Cn1ccc2c(Nc3ccc(Nc4cc(-c5ccncc5)nc(N)n4)cc3F)ccnc21,,O,,Cl,[Na+].[OH-],test
US20120225854A1,O=C1CNCCN1.O=S(=O)(Cl)c1ccc(Cl)nc1>>O=C1CN(S(=O)(=O)c2ccc(Cl)nc2)CCN1,,ClCCl,,CCN(CC)CC,,test
US20060089348A1,COc1c(-c2ccccc2)nc2ccccc2c1C(=O)O.O=C(Cl)C(=O)Cl>>COc1c(-c2ccccc2)nc2ccccc2c1C(=O)Cl,,ClCCl,,,,test
US06063779,CC(C)(C)OC(=O)N1CCC(=O)CC1.Nc1ccccc1SCc1ccccc1Br>>CC(C)(C)OC(=O)N1CCC(Nc2ccccc2SCc2ccccc2Br)CC1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130261178A1,OCCOCCc1ccc(F)cc1.Oc1ccc(OCc2ccccc2)cc1>>Fc1ccc(CCOCCOc2ccc(OCc3ccccc3)cc2)cc1,,ClCCl,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100094000A1,Cc1cc(-c2ccc(F)cc2)n(Cc2ccccc2)n1.O=C1CCC(=O)N1Br>>Cc1nn(Cc2ccccc2)c(-c2ccc(F)cc2)c1Br,,CC#N,,,,test
US20120122900A1,COC(=O)[C@@H](CI)NC(=O)OC(C)(C)C.N#CCc1ccccc1F>>COC(=O)[C@H](CC(C#N)c1ccccc1F)NC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04925879,CC(=O)C1(c2ccc(Cl)cc2)CCC1.CN(C)N>>CC(=NN(C)C)C1(c2ccc(Cl)cc2)CCC1,,CCO,,CC(=O)O,,test
US20010047031A1,CC(C)(C)OC(=O)N1CCC(O)C1.CC(O)=S>>CC(=O)SC1CCN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05002942,COc1ccc([C@H](Sc2cc(Oc3ccccc3)ccc2N)[C@@H](O)C(=O)OC2(C)CCC(C(C)C)CC2)cc1>>COc1ccc([C@H](Sc2cc(Oc3ccccc3)ccc2N)[C@@H](O)C(=O)O)cc1,,CO,O,[K+].[OH-],,test
US20080161332A1,c1ccc(CN2CCC3(CC2)OCc2ncccc23)cc1>>c1cnc2c(c1)C1(CCNCC1)OC2,[Pd],OCC(F)(F)F,,,,test
US20090076004A1,CCOC(=O)c1c(C=O)c2cc(B3OC(C)(C)C(C)(C)O3)ccc2n1-c1ccc(OC(C)C)cc1.FC(F)(F)c1ccc(Br)nc1>>CCOC(=O)c1c(C=O)c2cc(-c3ccc(C(F)(F)F)cn3)ccc2n1-c1ccc(OC(C)C)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20050107449A1,CN(C)C(=S)Cl.COC(=O)Cc1cccc(O)c1>>COC(=O)Cc1cccc(OC(=S)N(C)C)c1,,C1COCCO1,,CCN(CC)CC,,test
US20050059700A1,Cc1cccc2c1CCC(C(=O)O)CC2=O.ClCCl>>COC(=O)C1CCc2c(C)cccc2C(=O)C1,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20090099158A1,COC(=O)c1ccc2c(c1)CCN(C(=O)C1CCCCC1)C2>>O=C(O)c1ccc2c(c1)CCN(C(=O)C1CCCCC1)C2,,CC(C)O,,[K+].[OH-],,test
US20070078145A1,COCN(c1nccs1)S(=O)(=O)c1ccc(C(=O)CBr)cc1.N=C(N)Cc1c(Cl)cccc1Cl>>COCN(c1nccs1)S(=O)(=O)c1ccc(-c2cnc(Cc3c(Cl)cccc3Cl)[nH]2)cc1,,CN(C)C=O,,,,test
US20120122907A1,COc1ccc(Cn2cc(-c3csc(N)n3)cn2)cc1.O=C1CCC(=O)N1Cl>>COc1ccc(Cn2cc(-c3nc(N)sc3Cl)cn2)cc1,,CC#N,,,,test
US20050124616A1,O=C1CCC(=O)N1I.c1ccc(-c2cc3ncnc(NC4CCCC4)n3n2)cc1>>Ic1c(-c2ccccc2)nn2c(NC3CCCC3)ncnc12,,ClCCl,,,,test
US20030191155A1,COc1ccc(C(=O)N(NC(N)=O)c2ccc(OC)nc2)cc1>>COc1ccc(-c2nc(O)nn2-c2ccc(OC)nc2)cc1,,[Na+],[OH-],CCO,,test
US20110178083A1,CC(O)c1cccc2cnccc12>>CC(=O)c1cccc2cnccc12,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20020035104A1,CC(=O)Cl.CC(=O)n1c2ccccc2c2ccccc21>>CC(=O)c1ccc2c3ccccc3n(C(C)=O)c2c1,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20050277652A1,Nc1cc(Cl)ccn1.O=[N+]([O-])c1ccc(O)cc1>>Nc1cc(Oc2ccc([N+](=O)[O-])cc2)ccn1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US20050222159A1,CC(C)n1nc(-c2nc(S(C)(=O)=O)c(N)nc2-c2ccccc2)ccc1=O>>CC(C)n1nc(-c2[nH]c(=O)c(N)nc2-c2ccccc2)ccc1=O,,C1COCCO1,,Cl,[Na+].[OH-],test
US20090239854A1,C=Cc1ccc(CO)nc1.CN1CCc2[nH]c3ccc(CO)cc3c2C1>>CN1CCc2c(c3cc(CO)ccc3n2CCc2ccc(CO)nc2)C1,,CN1CCCC1=O,,[K+].[OH-],,test
US20110034440A1,C[N+](=O)[O-].Cc1ccccc1C=O>>Cc1ccccc1C=C[N+](=O)[O-],,CC(=O)O,O,C,O=C[O-].[NH4+],test
US20140364412A1,CC(C)(C)c1cc(NC(=O)OCC(Cl)(Cl)Cl)n(-c2ccc(Cl)c(OCCOC3CCCCO3)c2)n1.C[C@H]1CCCN1c1nnc2ccc(O[C@@H]3CC[C@H](N)c4ccccc43)cn12>>C[C@H]1CCCN1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4ccc(Cl)c(OCCOC5CCCCO5)c4)c4ccccc43)cn12,,C1COCCO1,ClCCl,CCN(C(C)C)C(C)C,,test
US20080064719A1,Cc1cc(O)c2c(n1)c(-c1ccc(-n3cccn3)cc1C)nn2C.O=P(Cl)(Cl)Cl>>Cc1cc(Cl)c2c(n1)c(-c1ccc(-n3cccn3)cc1C)nn2C,,CC#N,,,,test
US20120202832A1,COc1ccc(CN)cc1.Fc1cc2c(Nc3ccc(OCc4ccccn4)c(Cl)c3)ncnc2cn1>>COc1ccc(CNc2cc3c(Nc4ccc(OCc5ccccn5)c(Cl)c4)ncnc3cn2)cc1,,CS(C)=O,,,,test
US04517191,CCOC(=O)c1cn(N)c2nc(C)ccc2c1=O>>Cc1ccc2c(=O)c(C(=O)O)cn(N)c2n1,,O,,[Na+].[OH-],,test
US20050075342A1,CCc1ccc2c(-c3cccc(C#N)c3)c(S(C)(=O)=O)c(C(=O)OCC[Si](C)(C)C)nn12>>CCc1ccc2c(-c3cccc(C#N)c3)c(S(C)(=O)=O)c(C(=O)O)nn12,,O=C(O)C(F)(F)F,,,,test
US20130252937A1,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5c(C)cc(OCC6CCCO6)cc5C)ccc(F)c43)ccc21>>Cc1cc(OCC2CCCO2)cc(C)c1-c1ccc(F)c2c1CC[C@H]2Oc1ccc2c(c1)OC[C@H]2CC(=O)O,,CC(C)O,,,,test
US20100120859A1,CCOC(=O)CCCBr.COCCCc1cc(O)cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)c1>>CCOC(=O)CCCOc1cc(CCCOC)cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140031364A1,Fc1ccccc1N1CCNCC1.Nc1onc(-c2cccc(OC(F)(F)F)c2)c1C(=O)O>>Nc1onc(-c2cccc(OC(F)(F)F)c2)c1C(=O)N1CCN(c2ccccc2F)CC1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20030195251A1,C=CCC(C)(C)C=O.CCOC(=O)CC#N>>C=CCC(C)(C)C=C(C#N)C(=O)OCC,,Cc1ccccc1,,C1CCNCC1,CC(=O)O,test
US20130331359A1,C=O.CCOP(=O)([O-])OCC.CNCCCCl>>CCOP(=O)(CN(C)CCCCl)OCC,,C1COCCO1,,,,test
US20160137652A1,CCOC(=O)C(CC)C1CCNCC1.Fc1ccc2nccc(Cl)c2c1>>CCOC(=O)C(CC)C1CCN(c2ccnc3ccc(F)cc23)CC1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US20040266775A1,Cc1cn(-c2cccc3ncccc23)cc1C(=O)Cl.Cl.N=C(N)N>>Cc1cn(-c2cccc3ncccc23)cc1C(=O)NC(=N)N.Cl,,CO,,Cl,C[O-].[Na+],test
US20160002175A1,Cc1cccc(-c2cc(NCCCN)nc(N)n2)c1C.O=C=Nc1ccc(F)c(F)c1>>Cc1cccc(-c2cc(NCCCNC(=O)Nc3ccc(F)c(F)c3)nc(N)n2)c1C,,CO,,,,test
US04452788,CCn1c(=O)c2[nH]c(-c3ccc(S(=O)(=O)O)cc3)nc2n(CC)c1=O.CN(C)CCN>>CCn1c(=O)c2[nH]c(-c3ccc(S(=O)(=O)NCCN(C)C)cc3)nc2n(CC)c1=O,,CN(C)C=O,,O=S(Cl)Cl,,test
US20140005418A1,CC(=O)O.COc1ccc2c(c1)OCCC2(C#N)O[Si](C)(C)C>>COc1ccc2c(c1)OCCC2C(=O)O,,Cl,ClCCl,,,test
US20160046618A1,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cccc(F)c2F)C=CS1.COc1ccc(CCl)cc1>>COc1ccc(CN(C(=O)OC(C)(C)C)C2=N[C@](C)(c3cccc(F)c3F)C=CS2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040023964A1,Nc1ccc(F)c(-c2ccnc(Cl)n2)c1>>Nc1ccc(F)c(-c2ccncn2)c1,[Pd],,,CCN(CC)CC,[H][H],test
US20160168156A1,CCC(=O)NNC(=O)c1cnn2ccc(N3CCCC3c3cncc(F)c3)nc12.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CCc1nnc(-c2cnn3ccc(N4CCCC4c4cncc(F)c4)nc23)s1,,COCCOCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20050267095A1,CN(CCCCl)C1CCC1.Oc1ccc(C2(CNc3ccccn3)CCOCC2)cc1>>CN(CCCOc1ccc(C2(CNc3ccccn3)CCOCC2)cc1)C1CCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100076027A1,CCOC(=O)c1ccc(NC(=O)C(c2c3cc(F)c(F)cc3nn2-c2ccc(Cl)cc2)C2CCCCC2)c(F)c1>>O=C(O)c1ccc(NC(=O)C(c2c3cc(F)c(F)cc3nn2-c2ccc(Cl)cc2)C2CCCCC2)c(F)c1,,C1CCOC1,CO,[Li+].[OH-],,test
US20080200471A1,CC(=O)c1ccc2c(c1)CCO2.NO>>NC(=O)Cc1ccc2c(c1)CCO2,,CO,,Cl,c1ccncc1,test
US05191092,COc1cc2c(c3ccccc13)C=CCC2=O>>O=C1CCCc2c(O)cc3c(c21)CCCC3,,ClCCl,,BrB(Br)Br,CO,test
US20050203296A1,N#C[Cu]C#N.O=[N+]([O-])c1sc2ccccc2c1Br>>N#Cc1c([N+](=O)[O-])sc2ccccc12,,CN(C)C=O,,O,,test
US05252601,CC(=O)SCC1(C(=O)NCC(O)C(=O)OCc2ccccc2)CCc2ccccc2C1>>O=C(OCc1ccccc1)C(O)CNC(=O)C1(CS)CCc2ccccc2C1,,C1CCOC1,,[NH4+].[OH-],,test
US20070129341A1,CCOC(=O)C(Cc1ccc(N)nc1)c1cn(C2CCCCC2)cn1.Cl>>Cl.Nc1ccc(CC(C(=O)O)c2cn(C3CCCCC3)cn2)cn1,,O,,,,test
US20140348748A1,CI.COc1ccc2nc(-c3ccc(NC(=O)C(C)(C)C)c(Cl)n3)sc2c1>>COc1ccc2nc(-c3ccc(N(C)C(=O)C(C)(C)C)c(Cl)n3)sc2c1,,C1CCOC1,,[H-].[Na+],,test
US20090029987A1,CNC(=O)c1cc(CN2CCN(C)CC2)ccc1C.Cc1cc(C#N)cc(C)c1O[Si](C)(C)C(C)(C)C>>CNc1nc(-c2cc(C)c(O)c(C)c2)cc2ccc(CN3CCN(C)CC3)cc12,,C1CCOC1,,[Li]CCCC,,test
US20130210909A1,CCC(C)c1cc(/C=C/C(=O)c2ccc(C)cc2)cc2cc(C(=O)O)c(=O)oc12.CN>>CCC(C)c1cc(/C=C/C(=O)c2ccc(C)cc2)cc2cc(C(=O)NC)c(=O)oc12,,ClC(Cl)(Cl)Cl,,O=S(Cl)Cl,,test
US05409943,Nc1ncccc1OCc1ccccc1F.S=C=Nc1ccc(Cl)cc1>>Fc1ccccc1COc1cccnc1NC(=S)Nc1ccc(Cl)cc1,,CCOCC,,Cc1ccccc1,,test
US20060106046A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Fc1ccc(Br)cn1>>Fc1ccc(C2CCNCC2)cn1,,CCOCC,,O,[Li]CCCC,test
US05439910,C=C(OCC)c1cc(C(F)(F)F)ccn1>>CC(=O)c1cc(C(F)(F)F)ccn1,,CC(C)=O,,Cl,,test
US05071636,CCCCSC(NC(=O)C(C)C)C(=O)OC>>CCCCSC(NC(=O)C(C)C)C(=O)O,,CO,,[Na+].[OH-],,test
US20110275611A1,N#Cc1ccc(-c2cc(N3CCC[C@@H](N)C3)nc(N)n2)cc1F.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OC1CCCC1>>N#Cc1ccc(-c2cc(N3CCC[C@@H](NC(=O)OC4CCCC4)C3)nc(N)n2)cc1F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US07176310B1,CSc1ncc(C(=O)Nc2ccc(F)cc2)c(Cl)n1.NCC(O)c1ccccc1>>CSc1ncc(C(=O)Nc2ccc(F)cc2)c(NCC(O)c2ccccc2)n1,,CO,,O,,test
US20090130090A1,COc1ccc(Cl)cc1C(=O)Cl.O=C(NCC1CCCNC1)C(F)(F)F>>COc1ccc(Cl)cc1C(=O)N1CCCC(CNC(=O)C(F)(F)F)C1,,C1CCOC1,,,,test
US20120208838A1,CO.O=C(OCCCCCO/N=[N+](\[O-])N1CCC[C@H]1C(=O)O)c1ccc([N+](=O)[O-])cc1>>COC(=O)[C@@H]1CCCN1/[N+]([O-])=N/OCCCCCOC(=O)c1ccc([N+](=O)[O-])cc1,,ClCCl,,CCN(CC)CC,O=C1OCCN1P(=O)(Cl)N1CCOC1=O,test
US20160257658A1,C#CCO.CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1>>C#CCO[Si](C(C)C)(C(C)C)C(C)C,,ClCCl,,c1c[nH]cn1,,test
US20050159462A1,CS(=O)(=O)Cl.C[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](O)CCc1cccc2oc(-c3ccc(Cl)cc3)nc12>>C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](CCc1cccc2oc(-c3ccc(Cl)cc3)nc12)OS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US04866065,CCOC(=O)c1c(C)csc1N.CN.O=C(Cl)Cl>>CCOC(=O)c1c(C)csc1NC(=O)NC,,C1CCOC1,,CCN(CC)CC,,test
US20150105373A1,COC(=O)CN.O=[N+]([O-])c1cc(F)cnc1Cl>>COC(=O)CNc1ncc(F)cc1[N+](=O)[O-],,CCO,,CCN(CC)CC,Cl,test
US20160145218A1,NCC(=O)O.O=N[O-].O=c1[nH]c2ccc(F)cc2c(=O)o1>>O=C(O)Cn1nnc2ccc(F)cc2c1=O,,O,,CCN(CC)CC,Cl,test
US20120295877A1,CCOC(=O)CC(C#N)c1ccccc1.Cl>>CCOC(=O)CC(CN)c1ccccc1.Cl,[Pd],CCO,,,,test
US20150236274A1,Fc1cccc(Br)c1Cl.Oc1ccccc1>>Clc1c(Br)cccc1Oc1ccccc1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20030195176A1,C1CCOC1.CC(C)(C)OC(=O)COCC1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C.CC[Mg]Br>>CCC(O)(CC)COCC1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,,,test
US20100173901A1,BrCC1CCCO1.CC1(C)OB(c2cn[nH]c2)OC1(C)C>>CC1(C)OB(c2cnn(CC3CCCO3)c2)OC1(C)C,,CC#N,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040010147A1,CCOC(=O)c1ccnc(-c2cc(OC)c(Cl)c(OC)c2)c1>>COc1cc(-c2cc(C(=O)O)ccn2)cc(OC)c1Cl,,CCO,,[Na+].[OH-],,test
US20120277229A1,CC1CN(c2ccc3[nH]c(-c4nn(C5CCCCO5)c5ccc([N+](=O)[O-])cc45)nc3c2)CCO1>>CC1CN(c2ccc3[nH]c(-c4nn(C5CCCCO5)c5ccc(N)cc45)nc3c2)CCO1,[Pd],CCO,,[H][H],,test
US20060019985A1,Cc1c(N2CCC(CNC(=O)OC(C)(C)C)C2)c(F)cn2c(=O)c(C(=O)O)cc(C3CC3)c12>>Cc1c(N2CCC(CN)C2)c(F)cn2c(=O)c(C(=O)O)cc(C3CC3)c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110178063A1,Cc1cc2c(Br)ccnc2n1S(=O)(=O)c1ccccc1>>Cc1cc2c(Br)ccnc2[nH]1,,C1COCCO1,,[Na+].[OH-],,test
US04160829,Cc1nc(CO)no1.O=C=O>>O=C(O)Cc1nc(CO)no1,,C1CCOC1,CCCCCC,CN(C)CCN(C)C,[Li]CCCC,test
US20090270394A1,CC(C)(C)c1cc(C(=O)NC2(C(=O)Cl)CCCCC2)cc(C(C)(C)C)c1.NCc1cccc(C(F)(F)F)c1>>CC(C)(C)c1cc(C(=O)NC2(C(=O)NCc3cccc(C(F)(F)F)c3)CCCCC2)cc(C(C)(C)C)c1,,ClCCl,,,,test
US20160038504A1,Cc1ncc(N)cc1-c1cnc(F)c(N2CCOCC2)c1.OCCO>>Cc1ncc(N)cc1-c1cnc(OCCO)c(N2CCOCC2)c1,,C1COCCO1,,[H-].[Na+],,test
US20020006943A1,CC(=O)c1ccc[nH]1.C[Si](C)(C)OS(=O)(=O)C(F)(F)F>>C=C(O[Si](C)(C)C)c1ccc[nH]1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20090181963A1,CC(C)n1nnc2c(N3CCOCC3)nc(-c3ccc(N)cc3)nc21.Nc1ccc(N2CCOCC2)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)n1nnc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(N5CCOCC5)cc4)cc3)nc21,,ClCCl,,CCN(CC)CC,,test
US20070299039A1,CC(C)(C)OC(=O)n1ccc2ccc([N+](=O)[O-])cc21>>CC(C)(C)OC(=O)N1CCc2ccc(N)cc21,[Pd],CO,,[H][H],,test
US20150065519A1,CC1(C)OB(c2c[nH]c3ccccc23)OC1(C)C.O=S(=O)(Nc1ccc(-c2csc(Br)n2)c(Cl)c1)C(F)(F)F>>O=S(=O)(Nc1ccc(-c2csc(-c3c[nH]c4ccccc34)n2)c(Cl)c1)C(F)(F)F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20050113436A1,CCOC(=O)c1cc2cc(Br)ccc2[nH]1.Cc1ccc(CBr)cc1>>CCOC(=O)c1cc2cc(Br)ccc2n1Cc1ccc(C)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20150080393A1,CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4ccc(-c5ccc(C)c(CO)c5)cc4-n4ccc(C)n4)C(F)(F)F)nc(N)n3)CC2)CN1C(=O)OCc1ccccc1>>CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4ccc(-c5ccc(C)c(CO)c5)cc4-n4ccc(C)n4)C(F)(F)F)nc(N)n3)CC2)CN1,[Pd],CCOC(C)=O,,,,test
US20160168100A1,COc1ccc(C=O)c2occc12.O=C(O)CC(=O)O>>COc1ccc(/C=C/C(=O)O)c2occc12,,O,c1ccncc1,C1CCNCC1,Cl,test
US20160009663A1,CC(C)(C)OC(=O)N1CCN(c2cnc3ccc(C(=O)c4ccc(N)cc4F)cc3n2)CC1.O=C(Cl)c1cccc(F)c1>>CC(C)(C)OC(=O)N1CCN(c2cnc3ccc(C(=O)c4ccc(NC(=O)c5cccc(F)c5)cc4F)cc3n2)CC1,,c1ccncc1,,,,test
US20080096874A1,COC(=O)C1CCC(c2ccc([N+](=O)[O-])cc2)C1>>COC(=O)C1CCC(c2ccc(N)cc2)C1,[Pd],CCO,,,,test
US20100173888A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](NC(=O)c2ccc(-c3cccc(F)c3)nc2)CC1>>N[C@@H]1CC[C@H](NC(=O)c2ccc(-c3cccc(F)c3)nc2)CC1,,C1COCCO1,,Cl,,test
US04018825,CC(C)N.O=CC(=O)c1cc(OCc2ccccc2)cc(C(=O)O)c1>>CC(C)NCC(O)c1cc(OCc2ccccc2)cc(C(=O)O)c1,,CO,,,,test
US20090215759A1,CCOc1cc(C(C)(C)O)nc(Cl)n1.COc1cc(N)ccc1-n1cnc(C)c1>>CCOc1cc(C(C)(C)O)nc(Nc2ccc(-n3cnc(C)c3)c(OC)c2)n1,,CCO,CCOC(C)=O,Cl,,test
US20160002225A1,COc1ccc(Cn2nc(N[C@@H]3CCN(C(=O)OC(C)(C)C)C3)c3c(Oc4ccc(C(=O)O)cc4)ccnc32)cc1.Nc1ccccn1>>COc1ccc(Cn2nc(N[C@@H]3CCN(C(=O)OC(C)(C)C)C3)c3c(Oc4ccc(C(=O)Nc5ccccn5)cc4)ccnc32)cc1,,c1ccncc1,,O=P(Cl)(Cl)Cl,,test
US04337256,O=P(Cl)(Cl)Cl.OCc1cccc2c(-c3ccc(Br)cc3)nccc12>>ClCc1cccc2c(-c3ccc(Br)cc3)nccc12,,C1CCOC1,,O,[Na+].[OH-],test
US05869492,CC(=O)O.O=C(CBr)c1csc2ccccc12.S=C1NCCN1>>Br.C1=C(c2csc3ccccc23)N2CCN=C2S1.O.O,,CC(=O)O,,CCO,,test
US05734051,O=c1c2[nH]c([N+](=O)[O-])nc2n(C2CC2)c(=O)n1C1CC1>>Nc1nc2c([nH]1)c(=O)n(C1CC1)c(=O)n2C1CC1,,CO,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20100113462A1,CCOC(=O)C1(N)Cc2ccc(F)cc2C1.O=C(O)c1cccc2c1CCCC2>>CCOC(=O)C1(NC(=O)c2cccc3c2CCCC3)Cc2ccc(F)cc2C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050245602A1,C=CC(=O)OC.COc1ccc2c(c1)CCC(c1ccccc1)C2c1ccc(OS(=O)(=O)C(F)(F)F)cc1>>COC(=O)C=Cc1ccc(C2c3ccc(OC)cc3CCC2c2ccccc2)cc1,,CC#N,,,,test
US20120142672A1,C=C(C)B1OC(C)(C)C(C)(C)O1.COc1cc(-c2nnc3n2CCCC3c2ccccc2Br)ccc1-c1cnc(C)o1>>C=C(C)c1ccccc1C1CCCn2c(-c3ccc(-c4cnc(C)o4)c(OC)c3)nnc21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O,O=C([O-])[O-].[K+].[K+],test
US20130324546A1,CC=O.COc1cc(C2CCNCC2)ccc1Nc1ncc(C(F)(F)F)c(CCc2cccc(C(N)=O)c2)n1>>CCN1CCC(c2ccc(Nc3ncc(C(F)(F)F)c(CCc4cccc(C(N)=O)c4)n3)c(OC)c2)CC1,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05468589,COC(C)Oc1ccc(Br)cc1.CS(C)(=O)=O>>COC(=O)CCc1ccccc1,,CS(C)=O,,C1CCOC1,[H-].[Na+],test
US06300347B1,C[Si](C)(C)CCOCCl.Fc1ccc(-c2nc[nH]c2-c2ccncc2)cc1>>C[Si](C)(C)CCOCn1cnc(-c2ccc(F)cc2)c1-c1ccncc1,,C1CCOC1,CN(C)C=O,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20070191389A1,Cc1c(C2=CCN(C(=O)OC(C)(C)C)CC2)nnn1-c1cccnc1>>C1=C(c2cn(-c3cccnc3)nn2)CCNC1,,C1COCCO1,,Cl,,test
US20070293475A1,COc1cccc(O)c1.O=C(N1CCc2ccc(CCl)cc2CC1)C(F)(F)F>>COc1cccc(OCc2ccc3c(c2)CCN(C(=O)C(F)(F)F)CC3)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130131016A1,C=C(Br)C(F)(F)F.OB(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(F)(F)F,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US06699995B1,Cc1ccccc1O.Cc1nccn1-c1nc(-c2ccc(C(F)(F)F)cc2)c(CCCO)o1>>Cc1ccccc1OCCCc1oc(-n2ccnc2C)nc1-c1ccc(C(F)(F)F)cc1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20090203903A1,Cc1ccccc1B(O)O.Cc1nc(C#Cc2ccc(Cl)nc2)cs1>>Cc1nc(C#Cc2ccc(-c3ccccc3C)nc2)cs1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,O=C([O-])[O-].[K+].[K+],,test
US20050148627A1,CC(C)(O)c1cc(OC(F)(F)F)cc2c1OC(C(F)(F)F)C(C(=O)O)=C2>>CC(C)c1cc(OC(F)(F)F)cc2c1OC(C(F)(F)F)C(C(=O)O)=C2,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20060270646A1,CCOC(=N)c1cnc2c(c1)c(-c1ccoc1)cn2S(=O)(=O)c1ccccc1.NNC=O>>O=S(=O)(c1ccccc1)n1cc(-c2ccoc2)c2cc(-c3nnc[nH]3)cnc21,,CCO,,CCN(CC)CC,Cl,test
US20040122001A1,C[C@@H]1CN(c2csc3ccc(C#N)cc23)CCN1C(=O)C(F)(F)F>>C[C@@H]1CN(c2csc3ccc(C#N)cc23)CCN1,,CCO,,O,[BH4-].[Na+],test
US20140349987A1,CCOC(=O)c1cc(C(=O)/C=C/c2ccccn2)n(CC2CCCCC2)c1C>>CCOC(=O)c1cc(C(=O)CCc2ccccn2)n(CC2CCCCC2)c1C,[Pd],CO,,,,test
US04705853,CN1CC(CCCl)Oc2ncc(Br)cc2C1=O.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CN1CC(CCCl)Oc2ncc(Br)cc2C1=S,,CC#N,Cc1ccccc1,,,test
US20030114502A1,CI.Cc1ccc(Cl)c(O)c1>>COc1cc(Cl)ccc1C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110190278A1,CC(C)N(C(=O)OCc1ccccc1)[C@@H]1CC[C@H](CC(=O)O)N(C(=O)OC(C)(C)C)C1>>CC(C)N(C(=O)OCc1ccccc1)[C@@H]1CC[C@H](CCO)N(C(=O)OC(C)(C)C)C1,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US05256675,CC(=O)Nc1ncc(Sc2ccc(N)cc2)s1>>Nc1ccc(Sc2cnc(N)s2)cc1,,CC(=O)O,,Cl,[Na+].[OH-],test
US20140163173A1,BrP(Br)Br.CC12CC3CC(C)(C1)CC(c1cc(C(C)(C)C)cc(CO)c1O)(C3)C2>>CC12CC3CC(C)(C1)CC(c1cc(C(C)(C)C)cc(CBr)c1O)(C3)C2,,O,,ClCCl,,test
US20160108039A1,COCC1COC(C)(C)CN1.COc1cc(C(=O)O)cn2nc(NCc3cccc(Cl)c3)nc12>>COCC1COC(C)(C)CN1C(=O)c1cc(OC)c2nc(NCc3cccc(Cl)c3)nn2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20010018438A1,COC(=O)Cc1ccncc1.COC(OC)N(C)C>>COC(=O)C(=CN(C)C)c1ccncc1,,CN(C)C=O,,,,test
US20070072865A1,Nc1cccnc1.O=C(Cl)C(Cl)(Cl)Cl>>O=C(Nc1cccnc1)C(Cl)(Cl)Cl,,C1CCOC1,,CCN(CC)CC,,test
US20100273739A1,CCOC(=O)NC1CCc2ccc(OCCNC(=O)OC(C)(C)C)cc2C1Cc1ccc(Cl)c(Cl)c1.Cl>>CCOC(=O)NC1CCc2ccc(OCCN)cc2C1Cc1ccc(Cl)c(Cl)c1.Cl,,CC(C)O,ClCCl,,,test
US20160060265A1,O=c1c2cnn(C3CCCCO3)c2c2cnc(Cl)cc2n1CC(F)(F)F.OB(O)c1cccnc1F>>O=c1c2cnn(C3CCCCO3)c2c2cnc(-c3cccnc3F)cc2n1CC(F)(F)F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US20150094297A1,CN(C)C(=O)c1ccc(-c2nc(CO)cs2)cc1.COc1cc(O)c2cc(-c3cn4nc(OC)sc4n3)oc2c1>>COc1cc(OCc2csc(-c3ccc(C(=O)N(C)C)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1,,C1CCOC1,CC#N,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20050209241A1,CI.O=C(O)c1c(F)ccc(S(=O)O)c1F>>CS(=O)(=O)c1ccc(F)c(C(=O)O)c1F,,CO,O,O=C([O-])[O-].[Na+].[Na+],,test
US20100016279A1,CCN(CC)S(F)(F)F.OCCOCC1CCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1>>FCCOCC1CCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1,,ClCCl,,,,test
US06130237,COC(=O)c1cc2c3c(ccc2[nH]1)N(C(=O)OC(C)(C)C)CC3CON1C(C)(C)CCCC1(C)C>>COC(=O)c1cc2c3c(ccc2[nH]1)N(C(=O)OC(C)(C)C)CC3CO,[Zn],C1CCOC1,CC(=O)O,O,,test
US20020052364A1,COc1ccc2c(c1)C(c1ccc([N+](=O)[O-])cc1)=NNC(=O)C2.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>COc1ccc2c(c1)C(c1ccc([N+](=O)[O-])cc1)=NNC(=S)C2,,O,c1ccncc1,CCCCCC,CCOC(C)=O,test
US04618677,CCCCc1ccc(N=C=O)cc1.Cl.Cl.SCCCN1CCN(CCCc2ccc(Cl)cc2)CC1>>CCCCc1ccc(NC(O)=[SH]CCCN2CCN(CCCc3ccc(Cl)cc3)CC2)cc1.Cl.Cl,,ClCCl,,CCN(CC)CC,,test
US20090306150A1,CC(=O)O.CCOC(=O)Nc1ccc(NCc2ccc(F)cc2)nc1N>>CC(=O)O.CCOC(=O)Nc1ccc(NCc2ccc(F)cc2)nc1N,,CCO,,,,test
US20130035318A1,COC(=O)c1ccc(C2=CC[C@@]3(C)[C@@H](CC[C@]4(C)[C@@H]3CC[C@@H]3[C@H]5[C@H](C(C)C)CC[C@]5(NC(=O)CN5CCS(=O)(=O)CC5)CC[C@]34C)C2(C)C)cc1.O=C(O)C(F)(F)F>>CC(C)[C@@H]1CC[C@]2(NC(=O)CN3CCS(=O)(=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.O=C(O)C(F)(F)F,,C1CCOC1,O,[Li+].[OH-],,test
US20080004309A1,CC(=O)OC(C)=O.CCOC(=O)c1nc(C#N)c2c(ccn2Cc2cccc(OC)c2)c1O>>CCOC(=O)c1nc(C#N)c2c(ccn2Cc2cccc(OC)c2)c1OC(C)=O,,CCN(CC)CC,,,,test
US20090286778A1,COC(=O)c1cc(N)cc(CCc2cccc(NC(=O)OC(C)(C)C)c2)c1.Clc1ncc(Cl)c(Cl)n1>>COC(=O)c1cc(CCc2cccc(NC(=O)OC(C)(C)C)c2)cc(Nc2nc(Cl)ncc2Cl)c1,,CN(C)C=O,Cl,O=C([O-])[O-].[K+].[K+],,test
US20130117941A1,CCN(CC)CC(=O)c1ccc(OC)cc1.Cl>>CC[NH+](CC)CC(=O)c1ccc(OC)cc1.[Cl-],,O,,,,test
US20080119505A1,COc1ccc(C(=O)O)c(OC)n1.COc1ccc([C@H]2CCCC[C@H]2N)cc1OC>>COc1ccc(C(=O)N[C@@H]2CCCC[C@@H]2c2ccc(OC)c(OC)c2)c(OC)n1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20040106626A1,COc1cc(C#N)cc(OC)c1CN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.NO>>COc1cc(C(N)=NO)cc(OC)c1CN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,CO,,CCN(C(C)C)C(C)C,Cl,test
US20080287414A1,CCOC(=O)/C(Cl)=N\Nc1cc(F)ccc1OC/C=C/c1ccccc1>>CCOC(=O)C1=NN2c3cc(F)ccc3OC[C@@H]2[C@@H]1c1ccccc1,,Cc1ccccc1,,CCN(CC)CC,CCOC(C)=O,test
US04801609,Cc1ccc(CSC[C@H](N)C(=O)NC(=O)OC(C)(C)C)cc1>>Cc1ccc(CSC[C@H](N)C(N)=O)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050075375A1,CNN.N#Cc1ccccn1>>CNNC(=N)c1ccccn1,,CCO,,,,test
US04124596,O=C(O)Cc1cccc(C(=O)c2cc3cc(C(=O)O)sc3s2)c1>>O=C(O)Cc1cccc(C(=O)c2cc3ccsc3s2)c1,[Cu],,,,,test
US20130217668A1,COC(=O)CBr.O=C(OCc1ccccc1)N1CCNCC1>>COC(=O)CN1CCN(C(=O)OCc2ccccc2)CC1,,C1CCOC1,,,,test
US20060014777A1,BrCc1ccccc1.CCc1cc(C)c2c(c1)[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1NC2=O>>CCc1cc(C)c2c(c1)[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1N(Cc1ccccc1)C2=O,,C1CCOC1,,CCCCCC,[H-].[Na+],test
US20140161736A1,COC(=O)c1ccc(COc2cccc([C@@H](NC(=O)O[C@H]3CN4CCC3CC4)c3ccccc3)c2)cc1>>O=C(N[C@@H](c1ccccc1)c1cccc(OCc2ccc(C(=O)O)cc2)c1)O[C@H]1CN2CCC1CC2,,C1CCOC1,,Cl,[Li+].[OH-],test
US20100081644A1,CCOC(=O)C(C)(C)S(=O)(=O)c1ccc2ncsc2c1>>CC(C)(C(=O)O)S(=O)(=O)c1ccc2ncsc2c1,,C1COCCO1,O,[Li+].[OH-],,test
US20090275570A1,CC(C)(C)OC(=O)N[C@H](COS(C)(=O)=O)CC(COS(C)(=O)=O)Cc1ccccc1.NCc1ccccc1>>CC(C)(C)OC(=O)N[C@H]1CC(Cc2ccccc2)CN(Cc2ccccc2)C1,,[Na+],[OH-],,,test
US20090149468A1,CC(Nc1cc(-c2cc3nccn3c(N3CC4CC3CN4)n2)ccn1)c1ccccc1.CCC(C)=O>>CCC(C)N1C[C@@H]2C[C@H]1CN2c1nc(-c2ccnc(N[C@@H](C)c3ccccc3)c2)cc2nccn12,,ClC(Cl)Cl,ClCCl,CO,,test
US20080161302A1,CCCN(CCC)c1ccc([N+](=O)[O-])cn1>>CCCN(CCC)c1ccc(N)cn1,[Pd],CO,,,,test
US20040009991A1,CI.Cc1ccc(-c2c(C(=O)OCCC(c3ccccc3)c3ccccc3)c(C)nc(C)c2C(=O)N2CCNCC2)c(C)c1>>Cc1ccc(-c2c(C(=O)OCCC(c3ccccc3)c3ccccc3)c(C)nc(C)c2C(=O)N2CCN(C)CC2)c(C)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070225319A1,C1=C(c2c[nH]c3ccccc23)CCN(CCc2csc3ccccc23)C1.C=CCBr>>C=CCn1cc(C2=CCN(CCc3csc4ccccc34)CC2)c2ccccc21,,C1CCOC1,,CCCCCC,,test
US20130231342A1,CC(C)(C)OC(=O)Nc1nnc(CCl)o1.NC1CC1c1ccc(OCc2ccccc2)cc1>>CC(C)(C)OC(=O)Nc1nnc(CNC2CC2c2ccc(OCc3ccccc3)cc2)o1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090270411A1,C1CCN(C2CCNCC2)CC1.CC(C)(C)OC(=O)NCCCBr>>CC(C)(C)OC(=O)NCCCN1CCC(N2CCCCC2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080261952A1,Cc1nccc(-c2cccc(N)c2)n1.NCCc1ccc(Cl)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>Cc1nccc(-c2cccc(NC(=O)NCCc3ccc(Cl)cc3)c2)n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150191419A1,CC(C)(C)OC(=O)NCC(=O)CCC(=O)OCCCCCCCCCCCC(=O)O.Cl>>Cl.NCC(=O)CCC(=O)OCCCCCCCCCCCC(=O)O,,CCOC(C)=O,,CCOCC,,test
US20110275610A1,COC(=O)C1CNC1.N#Cc1ccc(C=O)cc1>>COC(=O)C1CN(Cc2ccc(C#N)cc2)C1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20070100141A1,CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(N)cc2F)CC1.O=C(O)[C@H]1CCOC1>>CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(NC(=O)[C@H]3CCOC3)cc2F)CC1,,ClCCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20120068170A1,CC1(C)c2ccccc2-c2cc3c(cc21)[nH]c1ccccc13.Clc1nc(-c2ccccc2)nc(-c2ccccc2)n1>>CC1(C)c2ccccc2-c2cc3c4ccccc4n(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3cc21,,CN(C)C=O,,[H-].[Na+],,test
US20150031708A1,COc1ncc(B2OC(C)(C)C(C)(C)O2)cc1C.Cc1ccc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)nc1Cl>>COc1ncc(-c2nc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)ccc2C)cc1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US04971993,CC(C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1.O=S(=O)(Cl)c1ccccc1>>CC(C)[C@H](NS(=O)(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
US20120316151A1,O=C(C[C@H]1CCN(C(=O)C2CC2)C1)NNC(=O)Nc1ccc(Br)cc1>>O=C(C1CC1)N1CC[C@H](Cc2n[nH]c(=O)n2-c2ccc(Br)cc2)C1,,O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20040110945A1,COC(=O)Cc1ccc2nc(Nc3ccc(F)cc3C)oc2c1F>>Cc1cc(F)ccc1Nc1nc2ccc(CC(=O)O)c(F)c2o1,,C1CCOC1,CO,[Na+].[OH-],,test
US20110015181A1,CC(C)(C)O.O=C(O)c1cc(N2CCC(F)(F)CC2)cc(COC2CCCCO2)n1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)Nc1cc(N2CCC(F)(F)CC2)cc(COC2CCCCO2)n1,,C1COCCO1,O,CCN(CC)CC,,test
US20070161627A1,COc1ccc2nccc(CCN3CCN(N)CC3)c2n1.O=C1CSc2ccc(S(=O)(=O)Cl)nc2N1>>COc1ccc2nccc(CCN3CCN(NS(=O)(=O)c4ccc5c(n4)NC(=O)CS5)CC3)c2n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090209524A1,Cc1nc(N)nc(O)c1Sc1ccc(CCl)cc1.[C-]#N>>Cc1nc(N)nc(O)c1Sc1ccc(CC#N)cc1,,CN(C)C=O,CS(C)=O,O,,test
US20070275966A1,C1COCCN1.O=C1O[C@H](c2ccccc2)CN1Cc1ccc(CBr)cc1>>O=C1O[C@H](c2ccccc2)CN1C(CN1CCOCC1)c1ccccc1,,CCOC(C)=O,,CC#N,,test
US20100113462A1,COC(=O)C1(N)Cc2cccc3cccc(c23)C1.Cc1cccc(C(=O)O)c1O>>COC(=O)C1(NC(=O)c2cccc(C)c2O)Cc2cccc3cccc(c23)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130150353A1,N#CCC(=O)C1CCSCC1.Nc1cc[nH]n1>>Nc1cc(C2CCSCC2)nc2ccnn12,,CC(=O)O,,,,test
US20090023795A1,COC(CBr)OC.N#Cc1cc(F)ccc1Oc1ccc2[nH]ncc2c1>>COC(Cn1ncc2cc(Oc3ccc(F)cc3C#N)ccc21)OC,,CC(=O)N(C)C,,[H-].[Na+],,test
US20130217680A1,CI.COC(=O)Cc1ccc(F)c(C#N)c1>>COC(=O)C(C)c1ccc(F)c(C#N)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20050131017A1,Cc1ccnc(-c2ccc(C[C@H]3[C@H](C[C@H](Cc4ccccc4)NC(=O)OC(C)(C)C)OC(C)(C)N3C(=O)OCc3ccccc3)cc2)c1>>Cc1ccnc(-c2ccc(C[C@H](NC(=O)OCc3ccccc3)[C@@H](O)C[C@@H](N)Cc3ccccc3)cc2)c1,,C1CCOC1,,CO,Cl,test
US20160158207A1,BrCc1ccccc1.CC(=O)N1CCc2c(c(Nc3ccc(-c4cnn(C)c4)cc3)nn2[C@H]2CCOC2)C1>>CC(=O)N1CCc2c(c(N(Cc3ccccc3)c3ccc(-c4cnn(C)c4)cc3)nn2[C@H]2CCOC2)C1,,CN(C)C=O,,[H-].[Na+],,test
US05792886,CC#N.COc1ccc2cc(Br)ccc2c1>>C=Cc1ccc2cc(OC)ccc2c1,Cl[Pd]Cl,O,,CCN(CC)CC,,test
US20040072818A1,Clc1ccc2c(N3CCNCC3)ccnc2c1.O=C=Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)N1CCN(c2ccnc3cc(Cl)ccc23)CC1,,C1CCOC1,,CCCCCC,CCOC(C)=O,test
US04372953,ClCc1ccccn1.Cn1nnnc1S>>Cn1nnnc1SCc1ccccn1,,CC(C)=O,,[I-].[K+],,test
US04153796,CCOc1c(C(N)=O)cnc2c1cnn2CC.NN>>CCn1ncc2c(NN)c(C(N)=O)cnc21,,CO,,O,,test
US05089487,COc1cc(C)cc2c1Oc1ccc(C(=O)CC(C)C)c(O)c1C(=O)OC2>>COc1cc(C)cc2c1Oc1ccc(C(O)CC(C)C)c(O)c1C(=O)OC2,,C1CCOC1,,CC(=O)O,[BH3-]C#N.[Na+],test
US20130225548A1,O=S(Cl)Cl.OCc1cc(Br)ccn1>>Cl.ClCc1cc(Br)ccn1,,CCOCC,,,,test
US20120129811A1,Nc1cc(S(N)(=O)=O)ccc1OC(F)(F)F.S=C(Cl)Cl>>NS(=O)(=O)c1ccc(OC(F)(F)F)c(N=C=S)c1,,ClC(Cl)Cl,O,O=C([O-])O.[Na+],,test
US20140336185A1,CC(C)(C)OC(=O)CN(Cc1ccc(-c2noc(N)n2)cc1)C(=O)c1ccc([N+](=O)[O-])cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)Nc2nc(-c3ccc(CN(CC(=O)OC(C)(C)C)C(=O)c4ccc([N+](=O)[O-])cc4)cc3)no2)cc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20130231329A1,CC(C)(C)OC(=O)N1C=CC(C(=N)N)N1C(=O)OC(C)(C)C.CN1CCC(OC(c2cccc(SCCN)c2)c2nc3cc(F)ccc3[nH]2)CC1>>CN1CCC(OC(c2cccc(SCCNC(=N)N)c2)c2nc3cc(F)ccc3[nH]2)CC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20070021443A1,C[C@H](c1cccnc1)n1c(=O)n(C(=O)OC(C)(C)C)c2ccc(N)nc21.N#Cc1ccc([N+](=O)[O-])c(F)c1>>C[C@H](c1cccnc1)n1c(=O)n(C(=O)OC(C)(C)C)c2ccc(Nc3cc(C#N)ccc3[N+](=O)[O-])nc21,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US06436966B1,CNC(N)=S.O=C(c1cccnc1)C(Br)c1ccccc1>>CNc1nc(-c2cccnc2)c(-c2ccccc2)s1,,CC#N,,Br,CCN(CC)CC,test
US20050043351A1,C1CCNCC1.O=C1CCc2cc(F)c(F)cc21>>O=C1CCc2cc(N3CCCCC3)c(F)cc21,,c1ccncc1,,,,test
US20090291940A1,Cc1cc(C)nc(N)c1.O=C1CCN(Cc2ccccc2)C1>>Cc1cc(C)nc(NC2CCN(Cc3ccccc3)C2)c1,,CC(=O)O,ClC(Cl)Cl,[Na+].[OH-],,test
US20120215003A1,C1CNCCN1.COc1ccc2[nH]c([S+]([O-])Cc3ncc(C)c(OC)c3C)nc2c1>>C1CNCCN1.COc1ccc2[nH]c([S+]([O-])Cc3ncc(C)c(OC)c3C)nc2c1,,CC(C)=O,,,,test
US20100056530A1,O=[N+]([O-])c1ncc(Oc2ccccc2Cl)cc1OCc1ccccc1>>Nc1ncc(Oc2ccccc2Cl)cc1OCc1ccccc1,[Zn],CC(=O)O,ClCCl,,,test
US20070225267A1,CC(C)(C)OC(=O)N1CC(=O)OC[C@@H]1[C@@H](OCc1ccccc1)[C@H](Cc1cc(F)cc(F)c1)N(Cc1ccccc1)Cc1ccccc1.CCI>>CC[C@H]1C(=O)OC[C@H]([C@@H](OCc2ccccc2)[C@H](Cc2cc(F)cc(F)c2)N(Cc2ccccc2)Cc2ccccc2)N1C(=O)OC(C)(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20140080704A1,CC(=O)C(F)(F)F.CC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(=O)/C=C(/C)C(F)(F)F,,ClCCl,,CCOCC,,test
US04942178,CC(C)c1cccc(N)c1.O=C(Cl)c1ccccc1C(F)(F)F>>CC(C)c1cccc(NC(=O)c2ccccc2C(F)(F)F)c1,,C1CCOC1,,CCN(CC)CC,,test
US20050187398A1,CCCCCCCCCCC12C=CC(CC1)C2.CO[Si](OC)(OC)C12C=CC(CC1)C2>>CCCCCCCCCCC12C=CC(CC1)C2.CO[Si](OC)(OC)C12C=CC(CC1)C2,,ClCCl,,,,test
US20110262352A1,BrCC1COc2ccccc2O1.N#Cc1cccnc1N1CCCNCC1>>N#Cc1cccnc1N1CCCN(CC2COc3ccccc3O2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US05698577,CC(C)(C)[Si](C)(C)N1C(=O)[C@@H]2[C@H]1[C@@H](O)CN2C(=O)OCc1ccccc1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)[Si](C)(C)N1C(=O)[C@@H]2[C@H]1[C@H](OS(=O)(=O)C(F)(F)F)CN2C(=O)OCc1ccccc1,,ClCCl,,c1ccncc1,,test
US08383629B2,CI.COC(=O)c1ccc2c(c1)C1(CCN(C(=O)/C=C/c3ccccc3C(F)(F)F)CC1)C(=O)N2>>COC(=O)c1ccc2c(c1)C1(CCN(C(=O)/C=C/c3ccccc3C(F)(F)F)CC1)C(=O)N2C,,C1CCOC1,,[H-].[Na+],,test
US20080255124A1,CS(=O)(=O)Cl.N#Cc1ccc(N(CCOc2ccc(N)cc2)CC(F)(F)F)cc1C(F)(F)F>>CS(=O)(=O)Nc1ccc(OCCN(CC(F)(F)F)c2ccc(C#N)c(C(F)(F)F)c2)cc1,,c1ccncc1,,,,test
US20140371199A1,CN1CCN(C(=O)c2ccc(-c3ccc4ncc(Br)n4n3)cc2)CC1.OB(O)c1ccc2[nH]cnc2c1>>CN1CCN(C(=O)c2ccc(-c3ccc4ncc(-c5ccc6[nH]cnc6c5)n4n3)cc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])O.[Na+],,test
US04990517,CI.O[C@@H]1CN(Cc2ccccc2)C[C@H]1NCCc1ccccc1>>CO[C@@H]1CN(Cc2ccccc2)C[C@H]1NCCc1ccccc1,,C1CCOC1,,[H][H],[H-].[Na+],test
US20150203511A1,CCC(=O)c1ccc(OC)c(C)c1.CCOC(=O)OCC>>CCOC(=O)C(C)C(=O)c1ccc(OC)c(C)c1,,C1CCOC1,,Cl,CC(C)(C)[O-].[K+],test
US20070093484A1,ClCCl.[N-]=[N+]=NCc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1C(=O)O>>[N-]=[N+]=NCc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1C(=O)Cl,CN(C)C=O,,,,,test
US20160046624A1,Cc1ccc(Oc2cnc3c(c2C(O)c2ccc(Cl)cc2)c(=O)n(CCCOC2CCCCO2)c(=O)n3C)cn1.O=CO>>Cc1ccc(Oc2cnc3c(c2Cc2ccc(Cl)cc2)c(=O)n(CCCOC=O)c(=O)n3C)cn1,[Zn],O=CO,,,,test
US20110077240A1,O=[N+]([O-])c1ccc(Oc2ccnc3cc(-c4ccc(C5OCCCO5)cn4)sc23)c(F)c1>>Nc1ccc(Oc2ccnc3cc(-c4ccc(C5OCCCO5)cn4)sc23)c(F)c1,[Fe],CCO,O,[Cl-].[NH4+],,test
US20060122065A1,C#CCOc1ccc(CCC(=O)Cl)cc1OC.NCc1ccc2c(c1)CCCC2>>C#CCOc1ccc(CCC(=O)NCc2ccc3c(c2)CCCC3)cc1OC,,CCN(CC)CC,,Cl,,test
US20160075692A1,Cc1cnc(CCl)o1.O=C1NCCN1c1cccc2c1cnn2-c1ccccc1F>>Cc1cnc(CN2CCN(c3cccc4c3cnn4-c3ccccc3F)C2=O)o1,,C1CCOC1,,[H-].[Na+],,test
US06630472B1,O=C(Cl)OCc1ccccc1.O=C(O)c1cccc(C(=O)O)n1>>O=C(O)C1CCCC(C(=O)O)N1C(=O)OCc1ccccc1,[Rh],[Na+],[OH-],O,,test
US05232929,COc1ccccc1C=O.NC1C(c2ccccc2)CC(=O)NC1c1ccccc1>>COc1ccccc1CNC1C(c2ccccc2)CC(=O)NC1c1ccccc1,,CO,,Cl,,test
US20100216843A1,CS(=O)(=O)c1ccc(CN)nc1.Cc1c(-c2ccnn2C)cc(C(=O)O)c(=O)n1-c1cccc(C(F)(F)F)c1>>Cc1c(-c2ccnn2C)cc(C(=O)NCc2ccc(S(C)(=O)=O)cn2)c(=O)n1-c1cccc(C(F)(F)F)c1,,CC#N,,Cl,O,test
US20030191118A1,COC(=O)[C@H](Cc1ccc(-c2c(OC)cccc2OC)cc1)NC(=O)c1c(Cl)cccc1Cl.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COC(=O)[C@H](Cc1ccc(-c2c(OC)cccc2OC)cc1)NC(=S)c1c(Cl)cccc1Cl,,Cc1ccccc1C,,O,,test
US05789634,Br[Mg]c1ccccc1.CC1=Cc2cccc(Cl)c2C1>>CC1=Cc2cccc(-c3ccccc3)c2C1,,CCOCC,,,,test
US20110275610A1,N#Cc1ccc(C=O)cc1.O=C(O)C1CNC1>>N#Cc1ccc(CN2CC(C(=O)O)C2)cc1,,CO,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20070078121A1,CCOC(=O)C1Cc2cc(-n3nc(C(C)(C)C)cc3NC(=O)Nc3cccc(Oc4cccnc4)c3)ccc2CN1C(=O)OC(C)(C)C.NCC(O)CO>>CC(C)(C)c1cc(NC(=O)Nc2cccc(Oc3cccnc3)c2)n(-c2ccc3c(c2)CCNC3C(=O)NCC(O)CO)n1,,CO,Cl,,,test
US20150065464A1,CCOC(=O)c1cnn(-c2ccc(C(=O)OC(C)(C)C)cn2)c1>>CCOC(=O)c1cnn(-c2ccc(C(=O)O)cn2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110158989A1,C[C@H]1CN(c2ccc(C#N)cc2)CCN1C(=O)OC(C)(C)C.Cl>>C[C@H]1CN(c2ccc(C#N)cc2)CCN1.Cl,,C1COCCO1,CCOCC,,,test
US04772600,C[C@H](C(=O)O)n1c(-c2ccc(Cl)cc2)nc2cccnc21.OCCO>>C[C@H](C(=O)OCCO)n1c(-c2ccc(Cl)cc2)nc2cccnc21,O=S(=O)(O)O,,,O,O=C([O-])O.[Na+],test
US20030092699A1,CCCCN1CCC(CNC(=O)c2cc(Cl)c(N)n3cc(CCC)nc23)CC1.Cc1ccc(S(=O)(=O)O)cc1>>CCCCN1CCC(CNC(=O)c2cc(Cl)c(N)n3cc(CCC)nc23)CC1.Cc1ccc(S(=O)(=O)O)cc1,,CO,,,,test
US04154740,O=C1CCC(N2C(=O)c3ccccc3C2=O)c2sccc21>>NC1CCC(=O)c2ccsc21,,CCO,,Cl,,test
US03931177,CC(=O)Oc1cc(C(=O)C(C)CC(=O)O)ccc1[N+](=O)[O-]>>CC(CC(=O)O)C(=O)c1ccc([N+](=O)[O-])c(O)c1,,[Na+],[OH-],Cl,,test
US20050075373A1,CCOC(C)=NC(=O)c1ccccc1.NNc1ccc(S(N)(=O)=O)cn1>>Cc1nc(-c2ccccc2)n(-c2ccc(S(N)(=O)=O)cn2)n1,,CO,ClCCl,O,,test
US20100113391A1,NCCn1c(=O)c2cc(F)c(NC3CCCCC3)cc2n(C2CCCC2)c1=O.O=S(=O)(Cl)c1nc[nH]n1>>O=c1c2cc(F)c(NC3CCCCC3)cc2n(C2CCCC2)c(=O)n1CCNS(=O)(=O)c1nc[nH]n1,,O,,C1CCOC1,CCN(CC)CC,test
US20020016328A1,CC[C@H](N)CO.COC(=O)c1c(Cl)cc(C)nc1Oc1c(C)cc(Cl)cc1C>>CCC(CO)Nc1cc(C)nc(Oc2c(C)cc(Cl)cc2C)c1C(=O)OC,,CCOC(C)=O,CN1CCCC1=O,,,test
US20040038963A1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc2c(n1)NCCC2>>CCOC(=O)C=Cc1ccc2c(n1)NCCC2,,Cc1ccccc1,,,,test
US20130053397A1,CC(C)=O.CCOC(=O)c1ccncc1>>C/C(O)=C/C(=O)c1ccncc1,,C1CCOC1,,C[O-].[Na+],,test
US20100075944A1,Nc1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)c(F)c2)ccn1.O=C(Cl)Oc1ccccc1.OCC1CNC1>>O=C(Nc1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)c(F)c2)ccn1)N1CC(CO)C1,,C1CCOC1,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US04474602,CO.O=C(O)c1cc(Cl)nc(Cl)c1>>COC(=O)c1cc(Cl)nc(Cl)c1,,ClCCl,,O=S(=O)(O)O,,test
US20100035857A1,O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2ccc(I)cc2)N1c1ccc(O)cc1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>O=C1[C@H](CC[C@H](O)c2ccc(F)cc2)[C@@H](c2ccc(I)cc2)N1c1ccc(OS(=O)(=O)C(F)(F)F)cc1,,ClCCl,,CCN(CC)CC,,test
US20140024650A1,CC(C)(C)OC(=O)NC1CCOCC1CO.Oc1ccc(-n2cc(Cl)cn2)cc1>>CC(C)(C)OC(=O)NC1CCOCC1COc1ccc(-n2cc(Cl)cn2)cc1,,Cc1ccccc1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20130072677A1,CNC(=O)C(C(=O)OC)N(C)C(=O)c1ccc(C#C/C=C/c2ccc(C=O)cc2)cc1.NC1CC1>>CNC(=O)C(C(=O)OC)N(C)C(=O)c1ccc(C#C/C=C/c2ccc(CNC3CC3)cc2)cc1,,ClC(Cl)Cl,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20110237584A1,O=C([O-])CCS(=O)(=O)NC1C=Nc2ccccc2N1OC(c1cccnc1)C(F)(F)F>>O=C(O)CCS(=O)(=O)NC1C=Nc2ccccc2N1OC(c1cccnc1)C(F)(F)F,,CO,,Cl,[Na+].[OH-],test
US20040235905A1,Oc1ccc(O)c(OCC(O)c2ccccc2)c1>>Oc1ccc2c(c1)OCC(c1ccccc1)O2,,Cc1ccccc1,,,,test
US20090274632A1,CC(=O)O.O=C(Cl)C(=O)Cl.O=S(=O)(O)c1ccc(O)cc1>>CC(=O)Oc1ccc(S(=O)(=O)Cl)cc1,CN(C)C=O,CC(=O)O,,CC(=O)OC(C)=O,,test
US04775671,CN1Cc2c(C(=O)n3ccnc3)ncn2-c2cccc(Cl)c2C1=O.COCC(N)=NO>>COCc1noc(-c2ncn3c2CN(C)C(=O)c2c(Cl)cccc2-3)n1,,CN(C)C=O,,,,test
US20160271270A1,Cc1csc2c(OCc3ccccc3)cc3c(c12)[C@H](CCl)CN3C(=O)CCCC(=O)N1C[C@@H](CCl)c2c1cc(NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)c1ccccc21>>Cc1csc2c(O)cc3c(c12)[C@H](CCl)CN3C(=O)CCCC(=O)N1C[C@@H](CCl)c2c1cc(NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)c1ccccc21,[Pd],C1CCOC1,O,O=C[O-].[NH4+],,test
US06340704B1,CCOC(=O)Cc1c(C(=O)OCC)nc2ccc(OC)cc2c1-c1ccc(F)cc1>>COc1ccc2nc(CO)c(CCO)c(-c3ccc(F)cc3)c2c1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20060287362A1,CN1CCC(CO)CC1.O=C(Cl)C(=O)c1cccs1>>CN1CCC(COC(=O)C(=O)c2cccs2)CC1,,ClC(Cl)Cl,,,,test
US04963566,C=CCOC1CCN(CC)c2c(CO[Si](C)(C)C(C)(C)C)cccc21>>C=CCOC1CCN(CC)c2c(CO)cccc21,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20040082607A1,CC(C)Cn1c(C(=O)OC(C)(C)C)c(-c2ccccc2)c2cc(OCc3ccccc3)ccc2c1=O>>CC(C)Cn1c(C(=O)O)c(-c2ccccc2)c2cc(OCc3ccccc3)ccc2c1=O,,O=C(O)C(F)(F)F,,,,test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4cc(-c5ccccc5)cnc4nn23)CC1.Cl>>Cl.O=c1cc(C2CCNCC2)n2nc3ncc(-c4ccccc4)cc3c2[nH]1,,C1COCCO1,CO,,,test
US04343803,CN(C)C(=S)Cl.Cc1cc(O)nc(C(Cl)(Cl)Cl)n1>>Cc1cc(OC(=S)N(C)C)nc(C(Cl)(Cl)Cl)n1,,CCOCC,,CCN(CC)CC,,test
US20150133512A1,COC(=O)c1c(C)nnn1-c1ccc(Br)cc1>>Cc1nnn(-c2ccc(Br)cc2)c1C(=O)O,,C1CCOC1,O,[Li+].[OH-],,test
US20100190814A1,CC(C)COC(=O)Cl.CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)NS(C)(=O)=O>>CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)N(C(=O)OCC(C)C)c1cc(Cl)ccc12)C(=O)NS(C)(=O)=O,CN(C)c1ccncc1,C1CCOC1,CCOC(C)=O,,,test
US20090137580A1,CC(C)(C)OC(=O)NCC#Cc1ncnc(Oc2ccc(N)c(Cl)c2)c1N>>CC(C)(C)OC(=O)NCc1cc2ncnc(Oc3ccc(N)c(Cl)c3)c2[nH]1,I[Cu]I,CN(C)C=O,O,,,test
US20120329826A1,C[C@@H](Oc1c([N+](=O)[O-])nc(Cl)c2c1cc(C(C)(C)C)n2C(N)=O)c1c(Cl)ccc(F)c1Cl>>C[C@@H](Oc1c(N)nc(Cl)c2c1cc(C(C)(C)C)n2C(N)=O)c1c(Cl)ccc(F)c1Cl,[Zn],CC(=O)O,,,,test
US04460579,CCOC(=O)CN1C(=O)C(N)CSc2ccccc21.CCOP(=O)(Cl)CCCCc1ccccc1>>CCOC(=O)CN1C(=O)C(NP(=O)(CCCCc2ccccc2)OCC)CSC2=CC=CCC21,,C1CCOC1,,CCN(CC)CC,,test
US20060105997A1,CC(C)(C)OC(=O)N1CC=CC1(C)c1ccccc1.OO>>CC(C)(C)OC(=O)N1CC(O)CC1(C)c1ccccc1,,C1CCOC1,,O,[Na+].[OH-],test
US20130029973A1,CC(C)N1CCC(N)CC1.CCOC(=O)CCCBr>>CCOC(=O)CCCNC1CCN(C(C)C)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090088425A1,CC(=O)OCCOc1ccc(C(C)C(O)(c2cnc(C)cn2)C(F)(F)F)c(Cl)c1>>Cc1cnc(C(O)(C(C)c2ccc(OCCO)cc2Cl)C(F)(F)F)cn1,,CCO,CCOC(C)=O,[K+].[OH-],,test
US20050234235A1,CO/C=C/c1nc(Br)[nH]c1C(=O)OC>>CO/C=C/c1nc(Br)[nH]c1C(=O)O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20160264518A1,COC(=O)/C=C/c1ccccc1NCc1cccc(C#N)c1>>N#Cc1cccc(CNc2ccccc2/C=C/C(=O)O)c1,,C1CCOC1,,[Li+].[OH-],,test
US20150119362A1,CCc1c(C)nc(-c2ccc(Cl)s2)nc1Nc1ccc(Cc2nc(C(=O)OC)c[nH]2)cc1.N>>CCc1c(C)nc(-c2ccc(Cl)s2)nc1Nc1ccc(Cc2nc(C(N)=O)c[nH]2)cc1,,CCO,,,,test
US08163737B2,CC(C)(C)CCN1C(=O)C(CC(=O)O)SC1c1cccc(F)c1NCCN1CCOCC1.O=C1Nc2ccccc2CCN1C1CCNCC1>>CC(C)(C)CCN1C(=O)[C@H](CC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)SC1c1cccc(F)c1NCCN1CCOCC1,,CCOC(C)=O,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
US20150274661A1,CC(c1ccc2[nH]c(C(=O)Nc3cc(F)cc(F)c3)cc2c1)C1CCNC1.N#CCBr>>CC(c1ccc2[nH]c(C(=O)Nc3cc(F)cc(F)c3)cc2c1)C1CCN(CC#N)C1,,CN1CCCC1=O,,,,test
US20120157451A1,COCCO.Nc1cc(O)n[nH]1>>COCCOc1cc(N)[nH]n1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150175615A1,CCOC(OCC)c1ccc(F)c(N2CC(N3CCN(C)[C@H](C)C3)C2)n1>>C[C@@H]1CN(C2CN(c3nc(C=O)ccc3F)C2)CCN1C,,O=CO,,,,test
US20030171418A1,CC(C)(C)[Si](C)(C)Cl.C[C@H](O)Cn1ncc2ccc(OCc3ccccc3)cc21>>C[C@@H](Cn1ncc2ccc(OCc3ccccc3)cc21)O[Si](C)(C)C(C)(C)C,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US05596009,COC(=O)COc1cccc2c1CCC(CO)C2.O=C1NC(=O)c2ccccc21>>COC(=O)COc1cccc2c1CCC(CN)C2,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030181726A1,COc1ccc(C(CC(C)N)c2ccc(OC)cc2)cc1.O=C(Nc1ccc(OC[C@@H]2CO2)cn1)OCc1ccccc1>>COc1ccc(C(CC(C)NC[C@H](O)COc2ccc(NC(=O)OCc3ccccc3)nc2)c2ccc(OC)cc2)cc1,,CO,,,,test
US20110288076A1,Nc1cc(Cl)ccc1[N+](=O)[O-].Oc1ccc(F)cc1>>Nc1cc(Oc2ccc(F)cc2)ccc1[N+](=O)[O-],,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20110263602A1,CCOC(=O)c1cn(Cc2ccc(OC)cc2)nc1C(F)(F)F>>COc1ccc(Cn2cc(C(=O)O)c(C(F)(F)F)n2)cc1,,C1COCCO1,O,Cl,[Li+].[OH-],test
US20120142671A1,NC(=O)[C@@H](Cc1ccccc1)NC(=O)OCc1ccccc1>>NC(=O)[C@H](N)Cc1ccccc1,[Pd],CO,,,,test
US20110071310A1,CC(C)(C)OC(=O)CN.N=C1C=CC=C2C1=Cc1ccccc12>>CC(C)(C)OC(=O)CN=C1c2ccccc2-c2ccccc21,,CCCCCC,CCOCC,Cl,ClCCl,test
US20150080549A1,CC(=O)OC(C)=O.CC(C)(C)SSC[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)O>>CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CSSC(C)(C)C)C(=O)O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090203705A1,BrC1CCC1.Oc1ccc(Br)nc1>>Brc1ccc(OC2CCC2)cn1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100278833A1,COC(=O)c1sc(-n2cnc3ccncc32)cc1OCc1ccccc1OC(F)(F)F.N>>NC(=O)c1sc(-n2cnc3ccncc32)cc1OCc1ccccc1OC(F)(F)F,,CO,,,,test
US20090275537A1,CN(C(=O)NCc1cccc(F)c1Cl)[C@H](COC(=O)Nc1cc2ccccc2cn1)CC(=O)OC(C)(C)C>>CN(C(=O)NCc1cccc(F)c1Cl)[C@H](COC(=O)Nc1cc2ccccc2cn1)CC(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160244446A1,COc1ccc([C@H](C)N2C[C@H]([C@H](C)O)CC2=O)cc1.Cn1cc2c(O)cc(Br)cc2n1>>COc1ccc([C@H](C)N2C[C@H]([C@@H](C)Oc3cc(Br)cc4nn(C)cc34)CC2=O)cc1,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04246263,C=Cc1ccncc1.OCCS>>OCCSCCc1ccncc1,,CCO,,C[O-].[Na+],,test
US20110224188A1,CC(=N)NO.CC(C)(C)OC(=O)NC1(C(=O)O)CC1>>Cc1noc(C2(NC(=O)OC(C)(C)C)CC2)n1,,CN(C)C=O,O,O=C(n1ccnc1)n1ccnc1,,test
US20090036453A1,C[Si](C)(C)CCOCn1c(-c2ccc(OC(F)F)c(OC3CC3)c2)c(O)c2c(=O)n(Cc3ccccc3)ncc21.C[Si](C)(C)CCOCn1c(-c2ccc(OC(F)F)c(OC3CC3)c2)cc2c(=O)[nH]ncc21>>O=c1[nH]ncc2c1c(O)c(-c1ccc(OC(F)F)c(OC3CC3)c1)n2Cc1ccccc1,,O,,,,test
US20140274703A1,C[Sn](C)(C)C.Nc1c(F)cc(Cl)c(F)c1Br>>Cc1c(N)c(F)cc(Cl)c1F,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,ClCCCl,,,,test
US20110257174A1,COC(=O)c1cccc(C(C)=O)c1O.O=C(Cl)c1cccnc1C(F)(F)F>>COC(=O)c1cccc(C(=O)CC(=O)c2cccnc2C(F)(F)F)c1O,,c1ccncc1,,C1CCC2=NCCCN2CC1,O,test
US20100105607A1,BrCCCOc1ccccc1.CO>>COCCCOc1ccccc1,,CO,,C[O-].[Na+],,test
US05134152,C[C@H](OS(C)(=O)=O)[C@@H](C)[C@H](c1ccc(Cl)cc1)C(O)n1cncn1>>C[C@@H]1O[C@@](Cn2cncn2)(c2ccc(Cl)cc2)[C@H]1C,,CN(C)C=O,,[H-].[Na+],,test
US20020161237A1,N#Cc1ccc2cc[nH]c2c1>>NCc1ccc2cc[nH]c2c1,[Ni],CCO,,N,,test
US20040058964A1,Cc1cc(OS(=O)(=O)c2ccc(Br)cc2)cc(=O)n1Cc1ccccc1.OCc1cccc(Cl)c1>>Cc1cc(OCc2cccc(Cl)c2)cc(=O)n1Cc1ccccc1,,CN(C)C=O,,Cl,[Na+].[OH-],test
US05753664,Cn1c(=O)c2c(ncn2Cc2ccc(C(=O)c3ccc(CBr)cc3)cc2)n(C)c1=O.c1ccc(N2CCNCC2)cc1>>Cn1c(=O)c2c(ncn2Cc2ccc(C(=O)c3ccc(-c4ccccc4)cc3CN3CCNCC3)cc2)n(C)c1=O,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05859011,COC(=O)CC(C)=O.COc1ccc(C(C)C)cc1CCl>>COC(=O)CC(=O)CCc1cc(C(C)C)ccc1OC,,C1CCOC1,CCCCCC,Cl,[H-].[Na+],test
US05439911,CCOC(=O)c1c(CC)ncnc1NCCc1ccc(CCOS(C)(=O)=O)cc1.C[S-]>>CCOC(=O)c1c(CC)ncnc1NCCc1ccc(CCSC)cc1,,CN(C)C=O,,O,,test
US04461724,Cc1ccc(S(=O)(=O)n2cnc(C[C@H](NC(=O)[C@H](COCc3ccccc3)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCCNC(=O)OCc3ccccc3)C(=O)OCc3ccccc3)c2)cc1>>Cc1ccc(S(=O)(=O)n2cnc(C[C@H](NC(=O)[C@@H](N)COCc3ccccc3)C(=O)N[C@@H](CCCCNC(=O)OCc3ccccc3)C(=O)OCc3ccccc3)c2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06187769B1,CCC1=COc2ccccc2C(=O)N1.ClCCCCBr>>CCC1=COc2ccccc2C(=O)N1CCCCCl,,CN(C)C=O,,[H-].[Na+],,test
US20090118325A1,CC(=O)O[C@H]1[C@H](Oc2cccn3ncnc23)SC[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>O[C@H]1[C@H](Oc2cccn3ncnc23)SC[C@@H](O)[C@@H]1O,,CO,,N,,test
US20070244131A1,COc1ccc(C=C[N+](=O)[O-])cc1F>>COc1ccc(CCN)cc1F,,C1CCOC1,CCOCC,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04134980,COc1cc2ncn(CCCCl)c(=O)c2cc1OC.COc1ccc(CCNCc2ccccc2)cc1OC>>COc1ccc(CCN(CCCn2cnc3cc(OC)c(OC)cc3c2=O)Cc2ccccc2)cc1OC,,Clc1ccccc1,,CO,ClC(Cl)Cl,test
US04436748,BrCc1ccccc1.COc1ccc(S)c(Cl)c1Cl>>COc1ccc(SCc2ccccc2)c(Cl)c1Cl,,CN(C)C=O,,[H-].[Na+],,test
US03956310,CC1(C)CC(O)CC(C)(C)N1.CCCCCCBr>>CCCCCCN1C(C)(C)CC(O)CC1(C)C,,CC#N,,,,test
US20150018422A1,CC(=O)OC(C)=O.CCOC(=O)CCc1cc[n+]([O-])c(C)c1>>CCOC(=O)CCc1ccnc(COC(C)=O)c1,,CC(=O)OC(C)=O,,,,test
US05364866,COc1cc(C2(C=O)C=CC=CC2)ccc1OCCCBr.Fc1ccc2c(C3CCNCC3)noc2c1>>COc1cc(C2(C=O)C=CC=CC2)ccc1OCCCN1CCC(c2noc3cc(F)ccc23)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04374829,C[C@H](N)C(=O)N1CCC[C@H]1C(=O)O.O=C(O)C(=O)Cc1ccccc1>>C[C@H](NC(Cc1ccccc1)C(=O)O)C(=O)N1CCC[C@H]1C(=O)O,,CO,O,[BH3-]C#N.[Na+],,test
US20100168197A1,CC(C)(C)C1OC(=O)[C@](c2ccccc2)([C@@H]2CCCC(F)(F)C2)O1>>O=C(O)[C@](O)(c1ccccc1)[C@@H]1CCCC(F)(F)C1,,CO,,[Na+].[OH-],,test
US20150105366A1,CON(C)C(=O)C1CCOCC1.Cn1cncc1Br>>Cn1cncc1C(=O)C1CCOCC1,,C1CCOC1,,CC[Mg]Br,,test
US20150141406A1,N#CCc1cc(-c2cn(C3CCCC3)c3c(C#N)c[nH]c(=O)c23)cs1.OO>>N#Cc1c[nH]c(=O)c2c(-c3csc(CC(N)=O)c3)cn(C3CCCC3)c12,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US06562823B1,BrCc1ccccc1.Oc1ccc2cccc(I)c2c1>>Ic1cccc2ccc(OCc3ccccc3)cc12,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20140315917A1,NC1CCOCC1.O=C=NCCCl>>O=C(NCCCl)NC1CCOCC1,,C1CCOC1,,Cc1ccccc1,,test
US04778891,CC[C@@](O)(C(=O)N[C@@H](C)c1ccccc1)c1cc2n(c(=O)c1CO)CCC21OCCO1>>CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)CCC1=O,,O=C(O)C(F)(F)F,,,,test
US20060116372A1,CCOC(=O)c1ccsc1.CC[Mg]Br>>OC1(c2ccsc2)CC1,,CCOCC,,O=S(=O)(O)O,,test
US20050113370A1,CC(C)(C)OC(=O)n1nc(-c2ccccc2)c2ccc(Nc3ccccc3)cc21.Cl>>Cl.c1ccc(Nc2ccc3c(-c4ccccc4)n[nH]c3c2)cc1,,CCOCC,CO,,,test
US20040127482A1,CC(C)(C)OC(=O)N1CC[C@H]2[C@@H](C1)c1cc(Br)cc3c1N2CC3.CCOc1ccc(B(O)O)c(C(F)(F)F)c1>>CCOc1ccc(-c2cc3c4c(c2)[C@@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2N4CC3)c(C(F)(F)F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,,,test
US20150284362A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[Si](C)(C)O[C@H]1CCNC1=O>>CC(C)(C)OC(=O)N1CC[C@H](O[Si](C)(C)C)C1=O,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,Cl,test
US20070099954A1,CC(C)(C)c1ccc2c(c1)CC[C@H]2NC(=O)Nc1cccc2c1cnn2C(=O)OCP(=O)(O)O.CCN(CC)CC>>CC(C)(C)c1ccc2c(c1)CC[C@H]2NC(=O)Nc1cccc2c1cnn2C(=O)OCP(=O)(O)O.CCN(CC)CC,,CO,,,,test
US20150051171A1,Cc1cccc(-n2nnn(C)c2=O)c1CBr.Oc1ccn(-c2ccc(OC(F)(F)F)cc2)n1>>Cc1cccc(-n2nnn(C)c2=O)c1COc1ccn(-c2ccc(OC(F)(F)F)cc2)n1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US05079247,FC(F)(F)c1cccc(CN2C(=S)c3cccc4cccc2c34)c1.NCCCn1ccnc1>>FC(F)(F)c1cccc(CN2C(=NCCCn3ccnc3)c3cccc4cccc2c34)c1,,CCO,,,,test
US20030220373A1,COC(=O)c1ccc(OCc2cccc(OCc3ccc4ccccc4n3)c2)c(OC)c1>>COc1cc(C(=O)O)ccc1OCc1cccc(OCc2ccc3ccccc3n2)c1,,C1CCOC1,O,[Na+].[OH-],,test
US05935952,CCOC(=O)C(=CNC1CC1)C(=O)c1cc(F)c(Br)c(C)c1F>>CCOC(=O)c1cn(C2CC2)c2c(C)c(Br)c(F)cc2c1=O,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110312944A1,CC(C)(C)c1cc(NC(=O)C2COCCN2)no1.O=S(=O)(Cl)c1ccc(Cl)cc1>>CC(C)(C)c1cc(NC(=O)C2COCCN2S(=O)(=O)c2ccc(Cl)cc2)no1,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,Cl,test
US20100152192A1,COc1cccc(/C=C/c2nc3sccn3c2C(=O)O)c1OCC1CC1.Nc1nc(C(F)(F)F)cs1>>COc1cccc(/C=C/c2nc3sccn3c2C(=O)Nc2nc(C(F)(F)F)cs2)c1OCC1CC1,CN(C)c1ccncc1,CN(C)C=O,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US05994349,CCOC(=O)C1C(=O)CC(=O)CC1C.Cc1ccc(N)c(S)c1>>CCOC(=O)C1C(=O)C2=C(CC1C)Nc1ccc(C)cc1S2,,CS(C)=O,,,,test
US06392104B1,O=C(O)C12CC3CC(CC(O)(C3)C1)C2>>OCC12CC3CC(CC(O)(C3)C1)C2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04005099,Cc1nc(CN(C)C)n(-c2cccc(Cl)c2C(=O)c2ccc(F)cc2)c1CN1C(=O)c2ccccc2C1=O>>Cc1nc(CN(C)C)n2c1CN=C(c1ccc(F)cc1)c1c(Cl)cccc1-2,,CCO,,NN,O,test
US04888345,CN(C)C=CC(=O)c1ccc(Cl)c(Cl)c1.NC(=O)c1[nH]cnc1N>>NC(=O)c1ncn2c(-c3ccc(Cl)c(Cl)c3)ccnc12,,CC(=O)O,,Cl,,test
US04479942,N[C@@H]1[C@@H](C(=O)O)O[C@@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)[C@@H]1O.O=C(N[C@@H](Cc1ccccc1)C(=O)O)OCc1ccccc1>>O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@@H](C(=O)O)O[C@@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)[C@@H]1O)OCc1ccccc1,,C1CCOC1,O,CCN(CC)CC,,test
US04210742,CC(C)C1CC=CCCC=CCC(C(C)C)N=N1>>CC(C)C(N)CCCCCCCCC(N)C(C)C,[Rh],CC(C)(C)O,,[H][H],,test
US20030114666A1,O=C(OCc1ccccc1)N1CCC(C(=NO)C2CC2)C1>>NC(C1CC1)C1CCNC1,[Ni],CO,,[H][H],,test
US03940259,CCc1cccc(CC)c1NCC1OCCO1.O=C(Cl)CCl>>CCc1cccc(CC)c1N(CC1OCCO1)C(=O)CCl,,CCOCC,O,C1COCCO1,O=C([O-])O.[Na+],test
US20110082312A1,CCOC(=O)CO.CS(=O)(=O)Cl>>CCOC(=O)CS(C)(=O)=O,,CCOC(C)=O,,CCN(CC)CC,,test
US20140066369A1,CC(C)(C)OC(=O)N1C2CCC1CN(C(=O)OC1(C(F)(F)F)CCC1)C2>>O=C(OC1(C(F)(F)F)CCC1)N1CC2CCC(C1)N2,,ClCCl,,C1COCCO1,Cl,test
US20100130489A1,Nc1cc(C(F)(F)F)c(Br)cc1-n1ccnc1.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2cc(C(F)(F)F)c(Br)cc2n2ccnc12,,CCOC(C)=O,,,,test
US20100222339A1,CCC(CC)c1cc(C)nc2c(-c3sc(NCCNC(=O)OC(C)(C)C)nc3C(F)(F)F)c(C)nn12.Cl>>CCC(CC)c1cc(C)nc2c(-c3sc(NCCN)nc3C(F)(F)F)c(C)nn12.Cl,,CO,,,,test
US20060241115A1,Clc1ccnc(Cl)n1.O=C(O)c1cccc2cc(O)ccc12>>O=C(O)c1cccc2cc(Oc3ccnc(Cl)n3)ccc12,,CS(C)=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US04171431,CN1CNC(=O)NC1=O.C[Si](C)(C)N(C(=O)C(F)(F)F)[Si](C)(C)C>>CN1CN=C(O[Si](C)(C)C)N=C1O[Si](C)(C)C,,c1ccncc1,,,,test
US04602092,CCOC(=O)CBr.CCOP([O-])CCCCc1ccccc1>>CCOC(=O)CP(=O)(CCCCc1ccccc1)OCC,,ClC(Cl)Cl,,CCN(CC)CC,C[Si](C)(C)Cl,test
US04252802,Cl.O=C(CON1C(=O)c2ccccc2C1=O)NOCc1ccccc1>>Cl.NOCC(=O)NOCc1ccccc1,,CO,,NN,,test
US20060135578A1,CCOP(=O)(/C=C/c1cn(-c2ccccc2)nc1NC(=O)c1ccc(OCc2nc(-c3ccccc3)oc2C)cc1)OCC.CI>>CCOP(=O)(/C=C/c1cn(-c2ccccc2)nc1N(C)C(=O)c1ccc(OCc2nc(-c3ccccc3)oc2C)cc1)OCC,,O,,CN(C)C=O,[H-].[Na+],test
US20060127990A1,CC(=O)OC(C)=O.COc1ccc(C(Cl)(c2ccccc2)c2ccc(OC)cc2)cc1.O=c1ccn([C@H]2C[C@H](O)[C@@H](CO)S2)c(=O)[nH]1>>COc1ccc(C(OC[C@H]2S[C@@H](n3ccc(=O)[nH]c3=O)C[C@@H]2OC(C)=O)(c2ccccc2)c2ccc(OC)cc2)cc1,,CO,,c1ccncc1,,test
US04329465,C=C1c2ccccc2CC(=O)Cc2ccccc21>>CC1c2ccccc2CC(=O)Cc2ccccc21,[Pd],CCO,,[H][H],,test
US04743586,CCOC(OCC)OCC.Cc1[nH]c(-c2cccnc2)nc1C(=O)NN>>Cc1nc(-c2cccnc2)n2cn[nH]c(=O)c12,,CCO,,,,test
US05254592,CCC(C)(C)c1ccc(Oc2ccncc2[N+](=O)[O-])c(C(C)(C)CC)c1>>CCC(C)(C)c1ccc(Oc2ccncc2N)c(C(C)(C)CC)c1,[Pd],CCO,,[H][H],,test
US20100286171A1,CCN(CC)S(F)(F)F.Cn1ccc(NC(=O)/C(=C/[C@H]2CCC(O)C2)c2ccc(S(=O)(=O)C3CC3)c(C3CC3)c2)n1>>Cn1ccc(NC(=O)/C(=C/[C@H]2CCC(F)C2)c2ccc(S(=O)(=O)C3CC3)c(C3CC3)c2)n1,,ClCCl,O,,,test
US20150203492A1,C[Si](C)(C)CCOCCl.Nc1[nH]ncc1Br>>C[Si](C)(C)CCOCn1ncc(Br)c1N,,C1CCOC1,,[H-].[Na+],,test
US06235771B1,CCCOCCCl.Sc1ccc(Br)cc1>>CCCOCCSc1ccc(Br)cc1,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20130303505A1,COc1cc(C(C)(C)c2cnc(SCc3c(F)cc(S(=O)(=O)NCCCOS(C)(=O)=O)cc3Cl)n2-c2ccc(F)cc2)ccc1F.c1ccncc1>>COc1cc(C(C)(C)c2cnc(SCc3c(F)cc(S(=O)(=O)NCCC[n+]4ccccc4)cc3Cl)n2-c2ccc(F)cc2)ccc1F.CS(=O)(=O)[O-],,CC#N,,,,test
US06355796B1,CCOC(=O)/C=C(\NC(=O)N(C)C)C(F)(F)F>>CN(C)c1nc(C(F)(F)F)cc(=O)o1,,O=P(Cl)(Cl)Cl,,ClP(Cl)(Cl)(Cl)Cl,,test
US05252580,CCI.c1ccc2c3c([nH]c2c1)CNCC3>>CCN1CCc2c([nH]c3ccccc23)C1,,CC#N,,O=C([O-])O.[Na+],,test
US20120202856A1,CC1(C)COB(c2cc(Cl)c(N)c([N+](=O)[O-])c2)OC1.Fc1cccc(F)c1Br>>Nc1c(Cl)cc(-c2c(F)cccc2F)cc1[N+](=O)[O-],c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US04216326,C1CC2(CCN1)OCCO2.Cc1ccc(S(=O)(=O)OCC(C)c2ccc(C(=O)c3ccccc3)cc2)cc1>>CC(CN1CCC2(CC1)OCCO2)c1ccc(C(=O)c2ccccc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05843607,O=C1CCC(=NN(c2ccccc2)c2ccccc2)CC1>>c1ccc2c(c1)[nH]c1cc3c(cc12)[nH]c1ccccc13,,CC(=O)O,,O=S(=O)(O)O,,test
US20030191160A1,Cc1cccc2c1nc(C=O)n2Cc1c(F)cccc1F.Cc1cccc2c1nc(CO)n2Cc1c(F)cccc1F>>Cc1cccc2c1nc(C=O)n2Cc1c(F)cccc1F.Cc1cccc2c1ncn2Cc1c(F)cccc1F,,CN(C)C=O,ClCCl,c1ccncc1,,test
US05112867,CC(=O)Oc1ccc(C(c2ccc(OC(C)=O)cc2)c2ccccc2C(=O)Cl)cc1.COc1cccc(N)c1>>COc1cccc(NC(=O)c2ccccc2C(c2ccc(O)cc2)c2ccc(O)cc2)c1,,ClCCl,,CCN(CC)CC,O,test
US20070161622A1,CC(C)(C)C(=O)Cl.COCCCOc1cc(C[C@@H](C[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CN)C(C)C)ccc1OC>>COCCCOc1cc(C[C@@H](C[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CNC(=O)C(C)(C)C)C(C)C)ccc1OC,,O,,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US20120101095A1,Cc1cccc(-c2nc(OCc3cnn(CCOC4CCCCO4)c3)nc3sc(C(N)=O)c(N)c23)n1>>Cc1cccc(-c2nc(OCc3cnn(CCO)c3)nc3sc(C(N)=O)c(N)c23)n1,,C1COCCO1,ClCCl,Cl,,test
US20080280917A1,COC(=O)Cc1ccc(O[Si](C)(C)C(C)(C)C)cc1>>CC(C)(C)[Si](C)(C)Oc1ccc(CCO)cc1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040157886A1,Fc1ccc(CC2CCNCC2)cc1.O=C(CCl)Nc1ccc2c(c1)OCC(=O)N2>>O=C(CN1CCC(Cc2ccc(F)cc2)CC1)Nc1ccc2c(c1)OCC(=O)N2,,CCOCC,,,,test
US20120295885A1,CO.Cn1cc(Br)nc1C(=O)C(Cl)(Cl)Cl>>COC(=O)c1nc(Br)cn1C,,CO,,C[O-].[Na+],,test
US06018020,C=CC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1C)NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)CCC(=O)OC(C)(C)C)C(C)(C)C)C(OC)OC>>C=CCC(C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)CCC(=O)O)C(C)(C)C,O,ClCCl,O=C(O)C(F)(F)F,,,test
US20090227575A1,CC(=O)Cl.Cn1ccc2c3nc(-c4ccc(N)cc4)nc(N4CCOCC4)c3ccc21>>CC(=O)Nc1ccc(-c2nc(N3CCOCC3)c3ccc4c(ccn4C)c3n2)cc1,,ClCCl,,CCN(CC)CC,,test
US05219876,N#CC(=Cc1cccnc1)c1ccc(Br)cc1>>N#CC(Cc1cccnc1)c1ccc(Br)cc1,,CO,,[BH4-].[Na+],,test
US20080070867A1,CCO.COC(=O)c1ccc(-c2cn(Cc3ccccc3)c(=O)n2Cc2ccc(C(F)(F)P(=O)(O)O)c(Br)c2)cc1>>CCOC(=O)c1ccc(-c2cn(Cc3ccccc3)c(=O)n2Cc2ccc(C(F)(F)P(=O)(O)O)c(Br)c2)cc1,O=S(=O)(O)O,,,,,test
US20100210619A1,CCCNCC1CC1.CCOC(=O)CCCNS(=O)(=O)c1ccc(NC(=O)c2cc(Cl)ncn2)c(C)c1>>CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(S(=O)(=O)NCCCC(=O)OCC)cc2C)ncn1,,CCO,,CC(C)NC(C)C,,test
US20070213321A1,O=C(CSc1nc2ccccc2s1)N1CCCc2ccccc21.O=C(OO)c1cccc(Cl)c1>>O=C(CS(=O)c1nc2ccccc2s1)N1CCCc2ccccc21,,ClCCl,,,,test
US20160009683A1,CCOC(=O)C(F)(C(=O)OC(C)(C)C)c1cnn(C)c(=O)c1>>CCOC(=O)C(F)c1cnn(C)c(=O)c1,,ClCCl,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],,test
US20100022598A1,CN(C)S(=O)(=O)n1cc(CC(C)(C)C)nc1C(=O)C(F)c1ccc(-c2ccc(F)cn2)cc1.C[Mg]Br>>CN(C)S(=O)(=O)n1cc(CC(C)(C)C)nc1C(C)(O)C(F)c1ccc(-c2ccc(F)cn2)cc1,,C1CCOC1,,,,test
US20090233903A1,CC1(S(=O)(=O)N2CC(=O)C2)CC1.CCOP(=O)(CC#N)OCC>>CC1(S(=O)(=O)N2CC(=CC#N)C2)CC1,,C1CCOC1,O,[H-].[Na+],,test
US20040266644A1,CCCCCCN(CC#N)CCCCCC.COS(=O)(=O)c1ccccc1>>CCCCCC[N+](C)(CC#N)CCCCCC.O=S(=O)([O-])c1ccccc1,,CCOC(C)=O,,,,test
US06075021,CN(C)C(=O)C1CN(Cc2ccccc2)C(=O)c2c1c1cc(F)ccc1n2C>>CN(C)C(=O)c1cn(Cc2ccccc2)c(=O)c2c1c1cc(F)ccc1n2C,,ClCCl,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20120142732A1,COc1ccc(CN)c(OC)c1.Cc1cnc(F)cc1I>>COc1ccc(CNc2cc(I)c(C)cn2)c(OC)c1,,CCOC(C)=O,,,,test
US20060154928A1,CC=O.CCCCCCCCCCCNC(=N)NC(=N)NCc1ccc(OC)cc1.Cl>>CCCCCCCCCCCNC1N=C(C)N=C(NCc2ccc(OC)cc2)N1.Cl,,CCO,,Cl,Cl,test
US20080096861A1,CC(C)N1CCC[C@@H](Cn2c(CN(C)[C@@H]3CCCc4cccnc43)nc3ccccc32)C1.CN(Cc1nc2ccccc2n1C[C@H]1CCCN(C[C@@H]2CCCN2)C1)[C@H]1CCCc2cccnc21>>CC(C)N1CCC[C@H]1CN1CCC[C@H](Cn2c(CN(C)[C@H]3CCCc4cccnc43)nc3ccccc32)C1,,CC(C)=O,,,,test
US20050209283A1,C=CCC(C)(C)C=O.[Li]CCCC>>C=CCC(C)(C)C(O)CCCC,,C1CCOC1,,[Cl-].[NH4+],,test
US05861109,Brc1ccc(I)cc1.CCCCCCCCOc1ccc(B(O)O)c(F)c1F>>CCCCCCCCOc1ccc(-c2ccc(Br)cc2)c(F)c1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20140038999A1,COc1c(Cl)ccc(-c2ccnc(C)c2C(=O)Cl)c1F.COc1ccc(CN)cc1>>COc1ccc(CNC(=O)c2c(-c3ccc(Cl)c(OC)c3F)ccnc2C)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20140051676A1,C1CC(COCC2CC2)CCN1.CN(c1ccccc1)c1nc(N)nc(-c2noc(C(Cl)(Cl)Cl)n2)n1>>CN(c1ccccc1)c1nc(N)nc(-c2noc(N3CCC(COCC4CC4)CC3)n2)n1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20060199829A1,COC(=O)c1cnc(N2CCc3[nH]c4ccc(CN5CCN(C)CC5)cc4c3C2)nc1.NO>>CN1CCN(Cc2ccc3[nH]c4c(c3c2)CN(c2ncc(C(=O)NO)cn2)CC4)CC1,,CO,O,ClCCl,[Na+].[OH-],test
US20130324546A1,CCc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1ncc(C(F)(F)F)c(CCc2ccccc2CC(N)=O)n1>>CCc1cc(C2CCNCC2)ccc1Nc1ncc(C(F)(F)F)c(CCc2ccccc2CC(N)=O)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100137313A1,CCN=C=O.NS(=O)(=O)c1cccc(Br)c1>>CCNC(=O)NS(=O)(=O)c1cccc(Br)c1,,CC(C)=O,O,[K+].[OH-],,test
US20100331326A1,FC(F)(F)c1ccncc1Br.O=C1NCCN1c1ccc2ncsc2c1>>O=C1N(c2ccc3ncsc3c2)CCN1c1cnccc1C(F)(F)F,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20090318475A1,COc1ccc(-c2c(-c3ccccc3)oc3ncnc(OC(C)C(C)OCCC(=O)OC(C)(C)C)c23)cc1>>COc1ccc(-c2c(-c3ccccc3)oc3ncnc(OC(C)C(C)OCCC(=O)O)c23)cc1,,C1COCCO1,,Cl,,test
US05308853,CCCCc1ncc(/C=C2/C(=O)N(CCCC)C(=O)N2CCCC)n1Cc1ccc(C(=O)OC(C)(C)C)cc1>>CCCCc1ncc(/C=C2/C(=O)N(CCCC)C(=O)N2CCCC)n1Cc1ccc(C(=O)O)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20140288074A1,CC(C)C=O.Cc1nn(C)c(Br)c1-c1c(F)cccc1Cl>>Cc1nn(C)c(C(O)C(C)C)c1-c1c(F)cccc1Cl,,C1CCOC1,CCOC(C)=O,[Li]CCCC,,test
US20110092479A1,COc1ccc(Cn2nc(OC)c3cc(NC(=O)OC(C)(C)C)cnc32)cc1>>COc1ccc(Cn2nc(OC)c3cc(N)cnc32)cc1,,O=C(O)C(F)(F)F,,,,test
US20070117760A1,CC(C)CCBr.CCOC(=O)c1cc([N+](=O)[O-])c[nH]1>>CCOC(=O)c1cc([N+](=O)[O-])cn1CCC(C)C,,CN(C)C=O,,[K],,test
US20100048636A1,CN.O=C[C@H]([C@@H](O)C1CCCCC1)N1C(=O)c2ccccc2C1=O>>CNC[C@H]([C@@H](O)C1CCCCC1)N1C(=O)c2ccccc2C1=O,,C1CCOC1,,CC(=O)O,,test
US20070117760A1,COc1ccc(CC(=O)Cl)cc1.COc1cccc(C(=O)Nc2cc(C(=O)Nc3cc(C(=O)Nc4cc(C(=O)NCCCN(C)C)n(C)c4)n(CCC(C)C)c3)n(C)c2)c1>>COc1ccc(CC(=O)Nc2cc(C(=O)Nc3cc(C(=O)Nc4cc(C(=O)NCCCN(C)C)n(C)c4)n(CCC(C)C)c3)n(C)c2)cc1,,ClCCl,,,,test
US20150353559A1,CC(C)(C)OC(=O)N1C[C@@H]2CCNCC[C@@H]2C1.O=C(O)/C=C/c1cccc(OC(F)(F)F)c1>>CC(C)(C)OC(=O)N1C[C@@H]2CCN(C(=O)/C=C/c3cccc(OC(F)(F)F)c3)CC[C@@H]2C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160009744A1,CC(C)[Si](O[C@H]1C[C@H](Nc2ncncc2C(=O)c2cc(CO[Si](C)(C)C(C)(C)C)c(Cl)s2)C[C@@H]1CO)(C(C)C)C(C)C.NS(=O)(=O)Cl>>NS(=O)(=O)OC[C@H]1C[C@@H](Nc2ncncc2C(=O)c2cc(CO)c(Cl)s2)C[C@@H]1O,,CN(C)C=O,,C1CCOC1,Cl,test
US20050182041A1,CC(C)(C)c1cc(C(=O)Cl)cc(C(C)(C)C)c1O.C[C@@H]1NC[C@H]1NC(=O)C(F)(F)F>>C[C@H]1[C@H](NC(=O)C(F)(F)F)CN1C(=O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1,,ClCCl,,CCN(CC)CC,,test
US20100331312A1,CC(=O)OCC(=O)Cl.CC(C)(C)[Si](C)(C)OCCc1ccc(-c2ccc3c(c2)CCNC3)cc1>>CC(=O)OCC(=O)N1CCc2cc(-c3ccc(CCO[Si](C)(C)C(C)(C)C)cc3)ccc2C1,,ClCCl,,CCN(CC)CC,,test
US20100261708A1,CC(C)(C)OC(=O)N1CCCN(C(=O)CC2CCCC2)CC1>>O=C(CC1CCCC1)N1CCCNCC1,,C1COCCO1,CO,Cl,,test
US06384051B1,CCN(CC)CC#CC(=O)O.N#Cc1cnc2ccc(N)cc2c1Nc1cccc(Br)c1>>CCN(CC)CC#CC(=O)Nc1ccc2ncc(C#N)c(Nc3cccc(Br)c3)c2c1,,C1CCOC1,c1ccncc1,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20140256729A1,COc1cc(C#N)cc(-c2ccc([C@@H]3C[C@H]3NC3CCC(NC(=O)OC(C)(C)C)CC3)cn2)c1>>COc1cc(C#N)cc(-c2ccc([C@@H]3C[C@H]3NC3CCC(N)CC3)cn2)c1,,C1COCCO1,,Cl,,test
US20090124595A1,CC(C)(C)OCCONC(=O)c1c(Nc2ccc(I)cc2F)c(F)c(=O)n2c1CCC2>>O=C(NOCCO)c1c(Nc2ccc(I)cc2F)c(F)c(=O)n2c1CCC2,,O=C(O)C(F)(F)F,,,,test
US04260619,CC(=O)Cc1ccc(O)cn1.Cl.NO>>CC(Cc1ccc(O)cn1)=NO.Cl,,CCO,,,,test
US04273728,COC(=O)C(F)(F)C(F)(F)OC.N>>COC(F)(F)C(F)(F)C(N)=O,,CCOCC,,,,test
US20110118245A1,CC(C)(c1cc(NC(=O)Oc2ccccc2)no1)C(F)(F)F.COc1cc2ncnc(Oc3cccc(N)c3)c2cc1O>>COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C(F)(F)F)on4)c3)c2cc1O,,CN(C)C=O,,,,test
US20160159809A1,Clc1nc(Cl)c2ccccc2n1.NC(c1ccccc1)c1ccccc1>>Clc1nc(NC(c2ccccc2)c2ccccc2)c2ccccc2n1,,C1CCOC1,,CCN(CC)CC,,test
US20030166936A1,N#Cc1c(Cl)c(F)cc([N+](=O)[O-])c1Cl>>N#Cc1c(Cl)c(N)cc(F)c1Cl,[Pd],CCO,,[H][H],,test
US20130072493A1,N#Cc1ncc(-c2ccc(NS(=O)(=O)c3cccc(Cl)c3Cl)cc2)nc1Cl.NN>>Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cccc(Cl)c4Cl)cc3)cnc12,,CC(C)O,O,,,test
US06352982B1,CC(C)I.CN(C)C=O.CON(C)C(=O)c1cc(O)ccc1NC(=O)OCc1ccccc1>>CON(C)C(=O)c1cc(OCC(C)C)ccc1NC(=O)OCc1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120041009A1,C=CC=O.O=c1nc(-c2cc(C(F)(F)F)nc(C3CC3)n2)[nH]o1>>O=CCCn1c(-c2cc(C(F)(F)F)nc(C3CC3)n2)noc1=O,,CCN(CC)CC,,CCO,,test
US20140275179A1,CC[Al](CC)CC.Cc1ccc(-c2snc(Cl)c2C#N)c(F)c1>>CCc1nsc(-c2ccc(C)cc2F)c1C#N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20040048930A1,CS(=O)(=O)Cl.NC1CC(F)(F)C1>>CS(=O)(=O)NC1CC(F)(F)C1,,CCN(CC)CC,,Cl,ClCCl,test
US20040087798A1,Cc1ncc(-c2cccc(N)c2)n1C.O=C(O)C=Cc1ccc(-c2ccccc2)cc1>>Cc1ncc(-c2cccc(NC(=O)C=Cc3ccc(-c4ccccc4)cc3)c2)n1C,,CC(=O)N(C)C,CCOC(C)=O,,,test
US05294612,Cc1nn(C2CCCC2O)c(N)c1C#N.OO>>Cc1nn(C2CCCC2O)c(N)c1C(N)=O,,O,,CC(=O)O,[Na+].[OH-],test
US05217976,CCc1cc2c(ccc(=O)n2Cc2ccc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc2)c(CC)n1.Cl>>CCc1cc2c(ccc(=O)n2Cc2ccc(-c3ccccc3-c3nnn[nH]3)cc2)c(CC)n1.Cl,,CO,,,,test
US06114325,CCCCCCCCCCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCN(CC)CC.Cl>>CCCCCCCCCCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCN(CC)CC.Cl,,CCOC(C)=O,,,,test
US04562185,CCI.NC(=O)C1(c2ccc(Cl)c(Cl)c2)OS(=O)NC1=O>>CCN1C(=O)C(C(N)=O)(c2ccc(Cl)c(Cl)c2)OS1=O,,CC#N,,CCN(CC)CC,,test
US06495549B1,CC(C)I.C[C@H]1CCC[C@@H](C)N1CCNC(=O)[C@@H]1CCCCN1c1nc2ccc(O)cc2o1>>CC(C)Oc1ccc2ncoc2c1.NC(=O)C1CCCCN1,,CN(C)C=O,,[H-].[Na+],,test
US20130072487A1,NCCCN1CCOCC1.O=C(Cl)CC(=O)Cl.O=C=NC1CCCCC1>>O=C1CC(=O)N(C2CCCCC2)C(=O)N1CCCN1CCOCC1,,ClCCl,,,,test
US20030119890A1,CCOC(=O)C(=O)Cl.CCc1cc(C#N)ccc1NC(=S)NC(C)(C)CC>>CCc1cc(C#N)ccc1N1C(=O)C(=O)N(C(C)(C)CC)C1=S,,ClCCl,,,,test
US20120133273A1,COC(=N)C(C)C.O=C(Cl)c1ccccc1>>COC(=NC(=O)c1ccccc1)C(C)C,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US20130210857A1,CC(C)c1nc2c(c(-c3ccc(F)cc3)c1C(OC(C)(C)C)C(=O)O)CNCC2(C)C.O=C(Cl)CCCc1ccccc1>>CC(C)c1nc2c(c(-c3ccc(F)cc3)c1C(OC(C)(C)C)C(=O)O)CN(C(=O)CCCc1ccccc1)CC2(C)C,,ClCCl,,CCN(CC)CC,CO,test
US20120046267A1,CC(C)(C)OC(=O)N1CCC(n2cc(B3OC(C)(C)C(C)(C)O3)cn2)CC1.Nc1ncc(Br)c2cc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)oc12>>CC(C)(C)OC(=O)N1CCC(n2cc(-c3cnc(N)c4oc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)cc34)cn2)CC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20030186988A1,NC(=S)NC1CCCCC1.O=CC(Br)c1ccc2c(=O)[nH]cnc2c1>>O=c1[nH]cnc2cc(-c3cnc(NC4CCCCC4)s3)ccc12,,CN(C)C=O,,,,test
US20010027196A1,Cc1c(OS(=O)(=O)C(F)(F)F)nc(N)nc1-c1ccco1.NCc1ccccc1>>Cc1c(NCc2ccccc2)nc(N)nc1-c1ccco1,,COCCOC,,O,,test
US20150307507A1,CC(C)(C)OC(=O)c1ncc(-c2ccccn2)s1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C(O)c1ncc(-c2ccccn2)s1,,ClCCl,,,,test
US06248740B1,Cc1nc2ccc(Cl)nn2n1.NCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1>>Cc1nc2ccc(NCCCN3CCC(OC(c4ccccc4)c4ccccc4)CC3)nn2n1,,CCCCO,CCOC(C)=O,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20080287458A1,CC(=O)c1ccc(Cl)cc1Nc1ccccc1.CC(C)(O)CNS(=O)(=O)c1ccc(C=O)cc1>>CC(C)(O)CNS(=O)(=O)c1ccc(C=CC(=O)c2ccc(Cl)cc2Nc2ccccc2)cc1,,CO,,[Na+].[OH-],,test
US04927838,COc1ccc(-c2c(/C=C/C(=O)O)ccc3cc(OC)ccc23)cc1.O=[N+]([O-])c1ccc(O)cc1>>COc1ccc(-c2c(/C=C/C(=O)Oc3ccc([N+](=O)[O-])cc3)ccc3cc(OC)ccc23)cc1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20100003250A1,NC(=O)Nc1cccc(Cn2ccc3c(N4CCOCC4)nc(Cl)nc32)c1.OCc1cccc(B(O)O)c1>>NC(=O)Nc1cccc(Cn2ccc3c(N4CCOCC4)nc(-c4cccc(CO)c4)nc32)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US06130239,C#CC(O)CC.O=C1Nc2ccc(F)c(I)c2/C1=C/c1ccc[nH]1>>CCC(O)C#Cc1c(F)ccc2c1/C(=C/c1ccc[nH]1)C(=O)N2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCN(CC)CC,CN(C)C=O,,,test
US04201712,O=S1C(Br)=CC2=C1OC=CN=C2c1ccccc1Cl.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>S=C1CN=C(c2ccccc2Cl)c2cc(Br)sc2O1,,COCCOCCOC,,O=C([O-])O.[Na+],,test
US20150329521A1,COC(C)(C)n1nc(Cn2ccc(C(F)(F)F)c(F)c2=O)n(C)c1=O.N#Cc1cc(O)cc(Cl)c1>>COC(C)(C)n1nc(Cn2ccc(C(F)(F)F)c(Oc3cc(Cl)cc(C#N)c3)c2=O)n(C)c1=O,,CN(C)C=O,,,,test
US20050026916A1,CI.S=C1N[C@@H](c2ccccc2)[C@@H](c2ccccc2)N1>>CSC1=N[C@@H](c2ccccc2)[C@@H](c2ccccc2)N1.I,,CCO,,,,test
US20160229855A1,CCOC(=O)c1nn(C2CCCCO2)cc1-c1ccnc2[nH]ccc12>>OCc1nn(C2CCCCO2)cc1-c1ccnc2[nH]ccc12,,C1CCOC1,,,,test
US20040235842A1,COc1ccc(C2CCOCC2)cc1N.N#CS.O=C(Cl)c1ccccc1>>COc1ccc(C2CCOCC2)cc1NC(=S)NC(=O)c1ccccc1,,CC(C)=O,,N,,test
US20150336938A1,CN(C)C(=O)Cl.COc1cc(Br)c(C2OCCO2)cc1OC>>COc1cc(C=O)c(C(=O)N(C)C)cc1OC,,C1CCOC1,,Cl,[Li]CCCC,test
US04618359,O=C(Cl)c1cc(Oc2ccc(C(F)(F)F)cc2[N+](=O)[O-])ccc1[N+](=O)[O-].OC1CCOC1>>O=C(OC1CCOC1)c1cc(Oc2ccc(C(F)(F)F)cc2[N+](=O)[O-])ccc1[N+](=O)[O-],,Cc1ccccc1,,CCN(CC)CC,,test
US20120094958A1,CCOP(=O)(CNc1ccc2cc([N+](=O)[O-])cc(-c3cccc4ccccc34)c2n1)OCC>>CCOP(=O)(CNc1ccc2cc(N)cc(-c3cccc4ccccc34)c2n1)OCC,[Ni],C1CCOC1,CO,,,test
US04160096,CCS(=O)O.Cc1ncc([N+](=O)[O-])n1CCBr>>CCS(=O)(=O)CCn1c([N+](=O)[O-])cnc1C,,CS(C)=O,,[Na],,test
US06001839,CC(C)n1cc(-c2ccc(O)cc2)c2c(N)ncnc21.O=[N+]([O-])c1ccccc1F>>CC(C)n1cc(-c2ccc(Oc3ccccc3[N+](=O)[O-])cc2)c2c(N)ncnc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020028807A1,CN1C(=O)c2cc(CCOc3ccnc4ccccc34)cnc2N(C2CC2)c2nc(Cl)ccc21.O=C(OO)c1cccc(Cl)c1>>CN1C(=O)c2cc(CCOc3cc[n+]([O-])c4ccccc34)cnc2N(C2CC2)c2nc(Cl)ccc21,,C1CCOC1,ClCCl,,,test
US20080045521A1,Cc1cccc(N(C)C(=O)OC(C)(C)C)n1.O=C(OO)c1cccc(Cl)c1>>Cc1cccc(N(C)C(=O)OC(C)(C)C)[n+]1[O-],,CC#N,,,,test
US20130345126A1,CC(C)(C)NS(C)(=O)=O.COC(=O)c1ccc(F)cc1>>CC(C)(C)NS(=O)(=O)CC(=O)c1ccc(F)cc1,,C1CCOC1,CCOC(C)=O,CC(=O)O,[Li]CCCC,test
US04558143,N.O=C1CCCc2occc21>>O=C1CCCc2[nH]ccc21,,CCO,,,,test
US20050004186A1,N#CBr.NNC(=O)c1ccc(F)c(F)c1Nc1ccc(Br)cc1F>>Nc1nnc(-c2ccc(F)c(F)c2Nc2ccc(Br)cc2F)o1,,C1COCCO1,,O,O=C([O-])O.[Na+],test
US20140051682A1,Nc1cc(Cl)ccc1[N+](=O)[O-].O=S(=O)(Cl)c1cc2ccccc2o1>>O=[N+]([O-])c1ccc(Cl)cc1NS(=O)(=O)c1cc2ccccc2o1,,CN(C)C=O,,[H-].[Na+],,test
US20030125370A1,CCN(CC)S(F)(F)F.N#CCN1CCC(O)CC1>>N#CCN1CCC(F)CC1,,ClCCl,,,,test
US20090181965A1,COc1cc(NC(N)=S)ccc1-n1cnc(C)c1.O=C1C(Br)CCCC1c1ccc(Cl)cc1Cl>>COc1cc(Nc2nc3c(s2)CCCC3c2ccc(Cl)cc2Cl)ccc1-n1cnc(C)c1,,CCO,,,,test
US20090181963A1,CN(C)CCNC(=O)c1ccc(N)cc1.COC(=O)c1cccc(-n2nnc3c(N4CCOCC4)nc(-c4ccc(N)cc4)nc32)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COC(=O)c1cccc(-n2nnc3c(N4CCOCC4)nc(-c4ccc(NC(=O)Nc5ccc(C(=O)NCCN(C)C)cc5)cc4)nc32)c1,,C1CCOC1,,CCN(CC)CC,,test
US20120283273A1,CC(=O)c1cc(Cl)ncn1.NCc1cnc2[nH]c(C(F)(F)F)cc2c1>>CC(=O)c1cc(NCc2cnc3[nH]c(C(F)(F)F)cc3c2)ncn1,,CCOC(C)=O,CN1CCCC1=O,CCN(C(C)C)C(C)C,,test
US20120077799A1,Cc1cnc(N)c(-c2ccc(Oc3ccccc3)cc2)c1.O=S(=O)(Cl)CCCl>>CC1=CN2CCS(=O)(=O)N=C2C(c2ccc(Oc3ccccc3)cc2)=C1,,C1CCOC1,,[H-].[Na+],,test
US20070142386A1,CCC[C@H](CO)Nc1nc(SCc2ccccc2)nc2nc(N)sc12.Cl>>CCC[C@H](CO)Nc1nc(SCc2ccccc2)nc2nc(Cl)sc12,,CC#N,O,O=N[O-].[Na+],,test
US20150126449A1,N#Cc1cccc(F)c1F.NN>>Nc1n[nH]c2c(F)cccc12,,CCO,,O,,test
US20100249118A1,Brc1cnc2[nH]ccc2c1.COc1cccc(C(=O)Cl)c1F>>COc1cccc(C(=O)c2c[nH]c3ncc(Br)cc23)c1F,,ClCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20130345123A1,CC(C)(C)OC(=O)N[C@H]1CC=C[C@H]2CCCCN2C1=O.Cl>>Cl.N[C@H]1CC=C[C@H]2CCCCN2C1=O,,C1COCCO1,,,,test
US05820785,C#Cc1ccc([C@@H]2CC[C@@H](CCCCC)CC2)cc1.C=O>>CCCCC[C@@H]1CC[C@@H](c2ccc(C#CCO)cc2)CC1,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US20080021032A1,COC(=O)c1cccc(CBr)c1.O=[N+]([O-])c1cc[nH]n1>>COC(=O)c1cccc(Cn2ccc([N+](=O)[O-])n2)c1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20090054407A1,CN1CCNCC1.O=C(O)c1ccc2[nH]ccc2c1>>CN1CCN(C(=O)c2ccc3[nH]ccc3c2)CC1,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20060105997A1,N[C@H](C(=O)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1)C1CC1.O=S(=O)(Cl)CCCl>>O=C([C@@H](NS(=O)(=O)CCCl)C1CC1)N1CC(c2cc(F)ccc2F)=C[C@H]1c1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040242608A1,COC(=O)c1ccc(C)c(-n2c(C)nc(OCc3ccc(F)cc3F)cc2=O)c1.O=C1CCC(=O)N1Br>>COC(=O)c1ccc(C)c(-n2c(C)nc(OCc3ccc(F)cc3F)c(Br)c2=O)c1,,ClCCl,,,,test
US20040006056A1,CCOC(=O)C(C#N)C1(c2ccc(Cl)cc2)CCOCC1>>O=C(O)CC1(c2ccc(Cl)cc2)CCOCC1,,O,OCCO,[K+].[OH-],,test
US20150291595A1,COc1ccc(C)cc1B(O)O.Cc1ccn2nc([C@H](C)Nc3ncnc4c3c(Br)cn4COCC[Si](C)(C)C)n(-c3ccccc3)c(=O)c12>>COc1ccc(C)cc1-c1cn(COCC[Si](C)(C)C)c2ncnc(N[C@@H](C)c3nn4ccc(C)c4c(=O)n3-c3ccccc3)c12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US04029787,CN1CCNCC1.NC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1>>CN1CCN(c2ccc(C(N)=O)cc2S(N)(=O)=O)CC1,,O,,,,test
US20100249402A1,C1COCCN1.Cc1nc(-c2ccc(OCCCCCOc3ccc(C#N)cc3)cc2)c(CBr)s1>>Cc1nc(-c2ccc(OCCCCCOc3ccc(C#N)cc3)cc2)c(CN2CCOCC2)s1,,CCOC(C)=O,,CC#N,,test
US20120122848A1,O=C(OCc1ccccc1)N1CC[C@]23CCCC[C@H]2[C@H]1Cc1cc([N+](=O)[O-])c(OCc2ccccc2)cc13>>Nc1cc2c(cc1OCc1ccccc1)[C@@]13CCCC[C@H]1[C@@H](C2)N(C(=O)OCc1ccccc1)CC3,[Ni],CO,,NN,O,test
US20140221339A1,CC(C)OCCN.Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2c(F)cccc2Cl)cc2[nH]c(Cl)nc12>>Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2c(F)cccc2Cl)cc2[nH]c(NCCOC(C)C)nc12,,CCOC(C)=O,,C1CCOC1,,test
US20020103247A1,BrCCCCCCBr.Oc1ccc2c(ccn2-c2ccc(F)cc2)c1>>Fc1ccc(-n2ccc3cc(OCCCCCCBr)ccc32)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05830901,BrCc1ccccc1.Fc1ccc(/C=C/c2ccncc2)cc1>>Fc1ccc(/C=C/C2=CCN(Cc3ccccc3)CC2)cc1,,CCO,CN(C)C=O,[BH4-].[Na+],,test
US20130203756A1,CC1(C)OB(C=CCN2Cc3c(Br)cccc3C2=O)OC1(C)C.CCCC[Sn](CCCC)(CCCC)c1ncco1>>CC1(C)OB(C=CCN2Cc3c(cccc3-c3ncco3)C2=O)OC1(C)C,,CN(C)C=O,,,,test
US20050245555A1,COc1ccc(Nc2ccnc(N[C@@H](C)C(C)(C)O)n2)cc1.O=C=Nc1ccccc1Cl>>COc1ccc(N(C(=O)Nc2ccccc2Cl)c2ccnc(N[C@@H](C)C(C)(C)O)n2)cc1,,CC(Cl)Cl,ClCCl,,,test
US04166131,CCC(C)(Cc1ccccc1)C(=O)O>>CCC1(C)Cc2ccccc2C1=O,,O,,,,test
US06037354,COc1ccccc1C1(O)CCC2(CC1)OCCO2>>COc1ccccc1C1=CCC(=O)CC1,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20110319379A1,CCOC(=O)c1cc(O)c2cn(CC)nc2c1.COc1ccc(CN(Cc2ccc(OC)cc2OC)C(=O)c2cnc(Cl)cn2)c(OC)c1>>CCOC(=O)c1cc(Oc2cnc(C(=O)N(Cc3ccc(OC)cc3OC)Cc3ccc(OC)cc3OC)cn2)c2cn(CC)nc2c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120129890A1,COC(=O)c1cccc(Cn2c(-c3ccccc3)cc3cc(CO[Si](C(C)C)(C(C)C)C(C)C)ccc32)n1>>COC(=O)c1cccc(Cn2c(-c3ccccc3)cc3cc(CO)ccc32)n1,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100130446A1,CC(O)c1cnc(-c2ccc(C(CC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)[nH]2)s1.O=C1CCC(=O)N1Cl>>CC(O)c1cnc(-c2cc(Cl)c(C(CC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)[nH]2)s1,,C1CCOC1,CCOC(C)=O,,,test
US20080015246A1,CCN(CC)c1ccc(B(O)O)cc1.CCOC(=O)c1ccc(-c2ccc(OCCCO[Si](C)(C)C(C)(C)C)c(Br)c2)cc1>>CCOC(=O)c1ccc(-c2ccc(OCCCO[Si](C)(C)C(C)(C)C)c(-c3ccc(N(CC)CC)cc3)c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20080081822A1,BrCC1CCCO1.CC(=O)SC(C)(C)C(=O)Nc1cc(C(C)(C)C)on1>>CC(C)(SCC1CCCO1)C(=O)Nc1cc(C(C)(C)C)on1,,CCO,,C,C[O-].[Na+],test
US20110166139A1,CNC(=O)c1ccccc1N.N#Cc1cnc(Cl)cc1Cl>>CNC(=O)c1ccccc1Nc1cc(Cl)ncc1C#N,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20030060498A1,CC(C)(C)OC(=O)NCCc1c[nH]c2ccc(S(=O)(=O)c3ccccc3)cc12.COS(=O)(=O)OC>>Cn1cc(CCNC(=O)OC(C)(C)C)c2cc(S(=O)(=O)c3ccccc3)ccc21,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150322089A1,Cc1ccc(N)c(=O)[nH]1.N=C(n1ccnc1)n1ccnc1>>Cc1ccc2nc(N)oc2n1,,C1CCOC1,,,,test
US20100093748A1,CN(C)S(=O)(=O)Cl.Clc1nc2ccccc2[nH]1>>CN(C)S(=O)(=O)n1c(Cl)nc2ccccc21,,CN(C)C=O,O,C1CN2CCN1CC2,,test
US04661610,COc1ccc(CCl)cc1OC>>COc1ccccc1OC,,Cc1ccccc1,,,,test
US20040048897A1,NS(=O)(=O)c1c(Cl)ccc(Nc2c(Cl)c(=O)c2=O)c1O.Nc1ccc(F)cc1>>NS(=O)(=O)c1c(Cl)ccc(Nc2c(Nc3ccc(F)cc3)c(=O)c2=O)c1O,,CS(C)=O,,,,test
US05273974,CC(=O)N1CCC(CCC(=O)Cl)CC1.c1ccc2c(c1)CCO2>>CC(=O)N1CCC(CCC(=O)c2ccc3c(c2)CCO3)CC1,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US04518607,CS(=O)(=O)OC(CCc1ccc(Cl)cc1)Cn1ccnc1>>CS(=O)(=O)OC(CCc1ccc(Cl)cc1)Cn1ccnc1,,ClCCl,,Cl,O=C([O-])[O-].[K+].[K+],test
US20090170791A1,CCOC(=O)C(=CN(C)C)C(=O)c1cc(I)ccc1F.CN>>CCOC(=O)c1cn(C)c2ccc(I)cc2c1=O,,CCO,,,,test
US20070197512A1,COC(=O)CCN1C(=O)C(C(C)C)Sc2ccccc21>>CC(C)C1Sc2ccccc2N(CCC(=O)O)C1=O,,CO,,[Na+].[OH-],,test
US20130005574A1,COC(=O)c1nc(C(C)=O)cc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1OC.COCCN(CCOC)S(F)(F)F.O=C(O)C(F)(F)F>>COC(=O)c1nc(C(C)(F)F)cc(N)c1OC,,ClCCCl,,,,test
US20100267963A1,CC(C)CC(C)C(Cl)C[N+](=O)[O-].OC1CSC(O)CS1>>CC(C)CC(C)C1SCC(O)C1[N+](=O)[O-],,Cc1ccccc1,,CCN(CC)CC,,test
US20050026916A1,ClCc1ccc(Br)cc1.S=C1N[C@@H](c2ccccc2)[C@@H](c2ccccc2)N1>>Brc1ccc(CSC2=N[C@@H](c3ccccc3)[C@@H](c3ccccc3)N2)cc1.Cl,,CCO,,,,test
US20160024103A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2nc(NCc3ccccc3)c(-c3cccc(C(=O)NC45CC(C4)C5)c3)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2nc(N)c(-c3cccc(C(=O)NC45CC(C4)C5)c3)cc12,,ClCCl,,O=S(=O)(O)C(F)(F)F,,test
US20140100250A1,COC(=O)[C@H]1CC[C@@H](C(=O)c2nccs2)C1.C[Mg]Br>>COC(=O)[C@H]1CC[C@@H](C(C)(O)c2nccs2)C1,,C1CCOC1,,[Cl-].[NH4+],,test
US20160222014A1,CC(C)(C)OC(=O)N1CCCC(=O)C1.CNC>>CN(C)C1CCCN(C(=O)OC(C)(C)C)C1,[Pd],CCO,,CC(=O)O,,test
US20130210634A1,COC(=O)C(=O)N(C)C.OC1CCCCC1>>CN(C)C(=O)C(=O)OC1CCCCC1,,CO,,O=S(=O)(O)O,,test
US04661596,O=C1CCCc2ccc(OCc3ccc4ccccc4n3)cc21>>OC1CCCc2ccc(OCc3ccc4ccccc4n3)cc21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20050171181A1,C1CCNC1.Cc1ccc(S(=O)(=O)OC[C@@H]2C[C@@H](c3ccc(CN4CCCC4)cc3)C2)cc1>>c1cc([C@@H]2C[C@@H](CN3CCCC3)C2)ccc1CN1CCCC1,,CC(=O)N(C)C,,,,test
US20130079338A1,C=CB1OC(C)(C)C(C)(C)O1.FC(F)Oc1ccc(Nc2ccc(Cl)nn2)cc1>>C=Cc1ccc(Nc2ccc(OC(F)F)cc2)nn1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20090137595A1,CC(=O)Nc1cn2nc(Oc3ccc(C)c(NC(=O)c4cc(C)nn4C)c3)ccc2n1.Cl>>Cc1cc(C(=O)Nc2cc(Oc3ccc4nc(N)cn4n3)ccc2C)n(C)n1.Cl,,CO,,CCOC(C)=O,,test
US20080306115A1,Cc1c(C(=O)N[C@H]2CCCC[C@H]2NC(=O)OC(C)(C)C)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(O)cc1.O=S(=O)(Cl)CCC(F)(F)F>>Cc1c(C(=O)N[C@H]2CCCC[C@H]2NC(=O)OC(C)(C)C)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1,,ClCCl,,,,test
US04552876,COc1ccc(CC(=O)c2ccc(OC)cc2)cc1>>COc1ccc(CCc2ccc(OC)cc2)cc1,[Zn],Cc1ccccc1,,C1COCCO1,Cl,test
US20070249687A1,BrBr.COC(=O)c1[nH]cc(C(=O)NCc2ccc(F)cc2)c(=O)c1O>>Cc1ncc(C(=O)O)c(O)c1Br,,O,,CC(=O)O,,test
US03989704,O=C1OC(c2ccccc2)c2ccccc21>>O=C(O)c1ccccc1Cc1ccccc1,[Pd],CCO,,,,test
US20080021032A1,Cn1ccc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(C)(=O)=O)c(Cl)c2)n1.Nc1ccn(CC2CC2)n1>>CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)Nc2ccn(CC3CC3)n2)cc1Cl,,ClCCl,,Cc1cccc(C)n1,O=C(Cl)C(=O)Cl,test
US20160052922A1,Cc1nn(C(C)C)c2nc(-c3cccc(O)c3)c(C(=O)N(C)C)c(NC3CCOCC3)c12.ClCC1CO1>>Cc1nn(C(C)C)c2nc(-c3cccc(OCC4CO4)c3)c(C(=O)N(C)C)c(NC3CCOCC3)c12,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20040176388A1,COc1cc2c(cc1N1C[C@H](C)N(C)[C@H](C)C1)N(C(C)=O)CC2>>COc1cc2c(cc1N1C[C@H](C)N(C)[C@H](C)C1)NCC2,,Cl,,O=C([O-])[O-].[K+].[K+],,test
US20070299051A1,C1CCNCC1.COC(=O)c1cc(C)c2c(c1)S(=O)(=O)Cc1cc(NCCCl)cc(Cl)c1O2>>COC(=O)c1cc(C)c2c(c1)S(=O)(=O)Cc1cc(NCCN3CCCCC3)cc(Cl)c1O2,,CN(C)C=O,,,,test
US20100113462A1,CCOC(=O)C1(NC(=O)c2cccc3c2CCCC3)[C@@H](C)c2ccccc2[C@H]1C>>C[C@H]1c2ccccc2[C@@H](C)C1(NC(=O)c1cccc2c1CCCC2)C(=O)O,,CCO,,O,[K+].[OH-],test
US20060135578A1,COCCl.O=Cc1cn(-c2ccccc2)nc1O>>COCOc1nn(-c2ccccc2)cc1C=O,,C1CCOC1,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20110053906A1,Nc1ccccc1O.O=c1[nH]c2nccc(Cl)c2c2ccccc12>>Nc1cccc(Oc2ccnc3[nH]c(=O)c4ccccc4c23)c1,,CN(C)C=O,CO,O=C([O-])[O-].[K+].[K+],,test
US20030139393A1,CCOC(=O)N1CCCC(=O)CC1.OCCO>>CCOC(=O)N1CCCC2(CC1)OCCO2,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,,,test
US05162320,CC(=O)OC(C)=O.CN(C)CCCNc1nnc(NCCCN(C)C)c2cc3ccccc3cc12>>CC(=O)N(CCCN(C)C)c1nnc(NCCCN(C)C)c2cc3ccccc3cc12,,c1ccncc1,,,,test
US20100130474A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(-c2n[nH]c(N)c2F)cn1>>Cc1ccc(-c2nn(C(=O)OC(C)(C)C)c(N)c2F)cn1,,ClCCl,,[K+].[OH-],,test
US20040209921A1,CCOC([O-])[O-].Cc1cccnc1CN(Cc1ncccc1C)C1CCN(C(=N)NO)CC1>>Cc1cccnc1CN(Cc1ncccc1C)C1CCN(c2ncon2)CC1,,C1COCCO1,,,,test
US20110306587A1,CC(C)(C)OC(=O)N1CC(c2nccnc2Cl)C1.COc1ccccc1O>>COc1ccccc1Oc1nccnc1C1CN(C(=O)OC(C)(C)C)C1,,CS(C)=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110319385A1,CCCc1nnc2c(=O)[nH]c3cc(C(=O)O)ccc3n12.c1ccc2c(c1)CCNC2>>CCCc1nnc2c(=O)[nH]c3cc(C(=O)N4CCc5ccccc5C4)ccc3n12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030171309A1,Cc1cccnc1Br.OCc1ccc(B(O)O)cc1>>Cc1cccnc1-c1ccc(CO)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20130035318A1,C=C(C)[C@@H]1CC[C@]2(N(CCN3CCS(=O)(=O)CC3)C(C)=O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(N(CCN3CCS(=O)(=O)CC3)C(C)=O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1COCCO1,,[Na+].[OH-],,test
US20090264432A1,CCOC(=O)COC(c1cccc(F)c1-c1cccc(C)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1>>Cc1cccc(-c2c(F)cccc2C(OCCO)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1,,CCO,,[BH4-].[Na+],,test
US08003783B2,CC12CCC3c4ccc(O)cc4CCC3C1CC(=Cc1ccccc1)C2=O.NS(=O)(=O)Cl>>CC12CCC3c4ccc(OS(N)(=O)=O)cc4CCC3C1CC(=Cc1ccccc1)C2=O,,CC(=O)N(C)C,CCOC(C)=O,Cc1ccccc1,O,test
US20080139505A1,CCCc1c(O)ccc(C(C)=O)c1O.N#Cc1cccc(C(OC2CCCCO2)c2ccc(CO)cc2)c1>>CCCc1c(OCc2ccc(C(OC3CCCCO3)c3cccc(C#N)c3)cc2)ccc(C(C)=O)c1O,,Cc1ccccc1,ClCCl,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20050049259A1,Fc1ccc(-c2nn3ccccc3c2-c2ccncc2)cc1.O=C1CCC(=O)N1Br>>Fc1ccc(-c2nn3c(Br)cccc3c2-c2ccncc2)cc1,,C1CCOC1,CCOCC,[Li]CCCC,,test
US20050054626A1,CCCC[C@@H]1CC2(CC[C@@H]1N)OCCO2.O=C(Cl)OCc1ccccc1>>CCCC[C@H]1CC2(CC[C@@H]1NC(=O)OCc1ccccc1)OCCO2,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20060199962A1,CCOC(=O)Nc1ccncc1.COc1cc(C(=O)CBr)ccc1[N+](=O)[O-]>>CCOC(=O)Nc1cc[n+](CC(=O)c2ccc([N+](=O)[O-])c(OC)c2)cc1.[Br-],,ClCCl,,,,test
US20080070928A1,C#C[C@@H](C)O[Si](C)(C)C(C)(C)C.CON(C)C(=O)c1ccc(NC(=O)c2cnccn2)cc1F>>C[C@H](C#CC(=O)c1ccc(NC(=O)c2cnccn2)cc1F)O[Si](C)(C)C(C)(C)C,,C1CCOC1,O,CCCCCC,[Li]CCCC,test
US05484689,Cc1ccccc1C.O=CC(=O)c1ccccc1>>Cc1ccc(C(O)C(=O)c2ccccc2)cc1C,Cl[Ti](Cl)(Cl)Cl,CC(Cl)Cl,,O,,test
US20070135477A1,COC(=O)c1cccc([N+](=O)[O-])c1NC(C)=O>>Nc1c(C(=O)O)cccc1[N+](=O)[O-],,CCO,,Cl,,test
US20080255335A1,O=[N+]([O-])c1cc(C23CC4CC(C2)CC(C25CC6CC(CC(C6)C2)C5)(C4)C3)cc(-c2cc(C34CC5CC(C3)CC(C36CC7CC(CC(C7)C3)C6)(C5)C4)cc([N+](=O)[O-])c2O)c1O>>Nc1cc(C23CC4CC(C2)CC(C25CC6CC(CC(C6)C2)C5)(C4)C3)cc(-c2cc(C34CC5CC(C3)CC(C36CC7CC(CC(C7)C3)C6)(C5)C4)cc(N)c2O)c1O,[Pd],CN(C)C=O,,,,test
US04533739,CC(=O)N(C)c1ccc(N)c(C)c1.ClC1=NCCC1>>CC(=O)N(C)c1ccc(NC2=NCCC2)c(C)c1.Cl,,Cc1ccccc1,,,,test
US04456612,CC=Cc1cc(C(=O)c2ccccc2F)c(Cl)c(Cl)c1O.O=C(OO)c1cccc(Cl)c1>>O=C(c1ccccc1F)c1cc2c(c(Cl)c1Cl)OC(CO)C2,,ClCCl,,,,test
US04742052,Cc1ccc(S(=O)(=O)Cl)cc1.O=C(OCc1ccc([N+](=O)[O-])cc1)N1CCC(CO)CC1>>Cc1ccc(S(=O)(=O)OCC2CCN(C(=O)OCc3ccc([N+](=O)[O-])cc3)CC2)cc1,,c1ccncc1,,,,test
US20110152299A1,CCO.CN(c1cncnc1)c1cc(F)cc(C#N)c1.[OH-]>>CN(c1cncnc1)c1cc(F)cc(C(=O)O)c1,,CO,ClCCl,Cl,,test
US20070073061A1,CC1(C)OC(=O)CC(=O)O1.CC1CC(=O)CCN1C(=O)OC(C)(C)C>>CC1CC(=C2C(=O)OC(C)(C)OC2=O)CCN1C(=O)OC(C)(C)C,,CO,,C,O=C[O-].[NH4+],test
US20040266826A1,CC(C)OB(OC(C)C)OC(C)C.Fc1ccc2ccsc2c1>>OB(O)c1cc2ccc(F)cc2s1,,CCCCCC,,Cl,[Li]CCCC,test
US20100113782A1,CCOC(=O)C1CCN(c2ccc(C(=O)Nc3ccc(I)c(C)c3)cn2)CC1>>Cc1cc(NC(=O)c2ccc(N3CCC(C(=O)O)CC3)nc2)ccc1I,,C1CCOC1,O,,,test
US20120202785A1,C[C@H](NC(=O)OC(C)(C)C)C1=NC=C2C=C(F)CCC3=C2N1CC3>>C[C@H](N)C1=NC=C2C=C(F)CCC3=C2N1CC3,,ClCCl,,Cc1ccccc1,O=C(O)C(F)(F)F,test
US20090233902A1,CCOc1ccc2[nH]cc(CC(C)(C(=O)OC)[N+](=O)[O-])c2c1>>CCOc1ccc2[nH]cc(CC(C)(N)C(=O)OC)c2c1,,CO,,,,test
US07160887B1,CC(C)(C)OC(=O)NCCc1cccc(Oc2ncccc2N)c1.CCOC(=O)CCCBr>>CCOC(=O)CCCNc1cccnc1Oc1cccc(CCNC(=O)OC(C)(C)C)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150344481A1,Fc1ccc(-c2cn(C3CC3)cn2)cc1.O=C1CCC(=O)N1Br>>Fc1ccc(-c2ncn(C3CC3)c2Br)cc1,,ClCCl,O,,,test
US05519034,COc1ccc(CCN)cc1Cl.O=C(Cl)C1(c2ccc(Cl)cc2)CCC1>>CN1CCc2cc(Cl)c(O)cc2C1C1(c2ccc(Cl)cc2)CCC1,,CCOCC,,CCN(CC)CC,O,test
US05614517,COC(=O)CCc1c2n(c(=O)c3ccccc13)CCc1ccccc1-2>>O=C(O)CCc1c2n(c(=O)c3ccccc13)CCc1ccccc1-2,,CCO,,[Na+].[OH-],,test
US20130292614A1,FC(=C(F)C(F)(F)F)C(F)(F)F.[O-]Cl>>FC(F)(F)C1(F)OC1(F)C(F)(F)F,,CC#N,,[Na+].[OH-],,test
US20040077669A1,C#CCOc1cc(Cl)ncn1.Oc1cc(Cl)cc(Cl)c1>>C#CCOc1cc(Oc2cc(Cl)cc(Cl)c2)ncn1,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US05162308,N#CBr.N#Cc1c(Br)[nH]c(Br)c1Br>>N#Cc1c(Br)c(Br)n(C#N)c1Br,,C1CCOC1,O,CC(C)(C)[O-].[K+],,test
US06200963B1,COc1ccc(N=Nc2c(S(=O)(=O)OC(C)C)cc3cc(N)ccc3c2O)cc1.O=C(Cl)c1ccccc1>>COc1ccc(N=Nc2c(S(=O)(=O)OC(C)C)cc3cc(NC(=O)c4ccccc4)ccc3c2O)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110034451A1,C1CCNC1.Cc1cc(Cl)nn2c(N)nnc12>>Cc1cc(N2CCCC2)nn2c(N)nnc12,,CN(C)C=O,,Br,O,test
US20030083365A1,C=CC#N.NCC1CCN(Cc2ccccc2)CC1>>N#CCCNCC1CCN(Cc2ccccc2)CC1,,CCO,,,,test
US05539112,CCCCCCI.Cc1c(F)c(N)c2c(=O)cc(-c3ccc(NC(=O)C(C)(C)C)c(F)c3)oc2c1F>>CCCCCCNc1c(F)c(C)c(F)c2oc(-c3ccc(NC(=O)C(C)(C)C)c(F)c3)cc(=O)c12,,O,,CN(C)C=O,[H-].[Na+],test
US20050277676A1,CC(C)(C)OC(=O)N1CCC(CO)CC1.CNC(=O)c1csc(-c2ccccc2N)n1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CNC(=O)c1csc(-c2ccccc2NC(=O)OCC2CCN(C(=O)OC(C)(C)C)CC2)n1,,C1CCOC1,,,,test
US06150373,CCOC(=O)Cc1ccc(Br)cc1.C[Mg]Br>>CC(C)(O)Cc1ccc(Br)cc1,,C1CCOC1,Cc1ccccc1,CCOCC,[Cl-].[NH4+],test
US20020022633A1,CC(C)(C)[Si](C)(C)OCc1ccc(Br)nc1.O=c1ccc2ccc(OCc3ccccc3)cc2[nH]1>>CC(C)(C)[Si](C)(C)OCc1ccc(-n2c(=O)ccc3ccc(OCc4ccccc4)cc32)nc1,[Cu],ClC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US20090275592A1,N#Cc1ccc2c(c1)CC(=O)N2.NO>>NC(=NO)c1ccc2c(c1)CC(=O)N2,,CO,,Cl,O=C([O-])O.[Na+],test
US20030171377A1,Cc1oc(-c2ccccc2)nc1CCO>>Cc1oc(-c2ccccc2)nc1CC=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04370326,NC(N)=S.O=C(CBr)CC(=O)NC1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=CCS[C@H]12>>Nc1nc(CC(=O)NC2C(=O)N3C(C(=O)OCc4ccc([N+](=O)[O-])cc4)=CCS[C@H]23)cs1,,C1CCOC1,,O,O=C([O-])O.[Na+],test
US20010034445A1,CN.O=C1c2ccccc2C(=O)N1c1cccc(CBr)n1>>CNCc1cccc(N)n1,,CCO,,NN,O,test
US20100130489A1,FC(F)(F)Oc1ccc2c(c1)nc(Cl)c1ncc(Br)n12.NCCCO>>OCCCNc1nc2cc(OC(F)(F)F)ccc2n2c(Br)cnc12,,C1COCCO1,CCOC(C)=O,,,test
US20050096293A1,O=[N+]([O-])c1ccc(CBr)cc1.Sc1ncnc2nc[nH]c12>>O=[N+]([O-])c1ccc(CSc2ncnc3nc[nH]c23)cc1,,CN(C)C=O,,O,O,test
US20070219210A1,CCN(C)C(=O)c1cc(-c2ccc(C#N)cc2)n(-c2cccnc2)n1>>CCN(C)C(=O)c1cc(-c2ccc(CN)cc2)n(-c2cccnc2)n1,[Pd],CO,,Cl,,test
US20040254153A1,CCCC(CC1(C(=O)O)CCCC1)C(=O)OCc1ccccc1.O=C(Cl)C(=O)Cl>>CCCC(CC1(C(=O)Cl)CCCC1)C(=O)OCc1ccccc1,,ClCCl,,,,test
US20090298836A1,CC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(C(F)(F)F)cc1>>CC(=O)/C=C/c1ccc(C(F)(F)F)cc1,,ClCCl,,,,test
US20090311217A1,CNC(=O)Nc1ccc2c(c1)C(=O)CO2.COc1ccc2[nH]c(-c3c(C)nn(C)c3C)c(C=O)c2c1>>CNC(=O)Nc1ccc2c(c1)C(=O)/C(=C/c1c(-c3c(C)nn(C)c3C)[nH]c3ccc(OC)cc13)O2,Cl,CCO,,CCOC(C)=O,,test
US20050080106A1,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].N#Cc1ccc(NC(=O)c2cc(OCc3ccccc3)cc(OCc3ccccc3)c2)nc1>>O=C(Nc1ccc(-c2nnn[nH]2)cn1)c1cc(OCc2ccccc2)cc(OCc2ccccc2)c1,,Cc1ccccc1,,,,test
US20110136800A1,O=[N+]([O-])O.c1ccc2c(c1)Cc1ncccc1-2>>O=[N+]([O-])c1ccc2c(c1)Cc1ncccc1-2,,O=S(=O)(O)O,,,,test
US20110313165A1,NC1(c2ccccc2)CCC(=O)N2CCCC21>>NC1(c2ccccc2)CCCN2CCCC21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040102479A1,O=[Cr](=O)=O.OCCCC(F)(F)C(F)(F)F>>O=C(O)CCC(F)(F)C(F)(F)F,,CC(C)=O,,O=S(=O)(O)O,,test
US06165941,Fc1ccc(-c2ncc(C(F)(F)F)cc2Cl)cc1.O=[N+]([O-])O>>O=[N+]([O-])c1cc(-c2ncc(C(F)(F)F)cc2Cl)ccc1F,,O=S(=O)(O)O,,,,test
US20080153850A1,CNCCO.O=C(O)c1ccc(Cl)nc1Cl>>CN(CCO)c1nc(Cl)ccc1C(=O)O,,CC#N,,,,test
US20030216441A1,Cn1cncc1C=O.N#CC1=C(c2cccc3ccccc23)CN(C(=O)CNCc2ccc(C#N)cc2)CC1>>Cn1cncc1CN(CC(=O)N1CCC(C#N)=C(c2cccc3ccccc23)C1)Cc1ccc(C#N)cc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20110136764A1,COc1ccc([N+](=O)[O-])c2c1CN(C)C2=O>>COc1ccc(N)c2c1CN(C)C2=O,[Pd],CCOC(C)=O,CO,,,test
US05616599,CCCCc1nc(C(C)(O)CC)c(C#N)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCCc1nc(C(C)(O)CC)c(C#N)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,CC(=O)O,,,,test
US20050209241A1,CC(C)(C)OC(=O)N1CCN(c2cnc(C(N)=O)cn2)CC1.Cl>>Cl.NC(=O)c1cnc(N2CCNCC2)cn1,,C1COCCO1,,,,test
US20160095858A1,Cc1cc(C)c(Cn2c(C(=O)NS(=O)(=O)c3cccc([N+](=O)[O-])c3)cc3ccc(C#N)cc32)c(C)c1>>Cc1cc(C)c(Cn2c(C(=O)NS(=O)(=O)c3cccc(N)c3)cc3ccc(C#N)cc32)c(C)c1,[Pd],CO,,[H][H],,test
US20110319393A1,CC(C)(C)OC(=O)N1CCC(NC(=O)CCCN2CCN(c3ccc(C(F)(F)F)cc3)CC2)CC1>>O=C(CCCN1CCN(c2ccc(C(F)(F)F)cc2)CC1)NC1CCNCC1,,CCOC(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20040106672A1,CO.O=C(O)c1ccoc1-c1cccc([N+](=O)[O-])c1>>COC(=O)c1ccoc1-c1cccc([N+](=O)[O-])c1,O=S(=O)(O)O,,,,,test
US20050059702A1,Cc1cccnc1C1CCCC(c2ncccc2C)N1Cc1ccccc1[N+](=O)[O-]>>Cc1cccnc1C1CCCC(c2ncccc2C)N1Cc1ccccc1N,[Pd],CO,,,,test
US20100190825A1,CCO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C)c(Cl)cc3[N+](=O)[O-])CC2)CC1>>CCO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C)c(Cl)cc3N)CC2)CC1,[Ni],CCO,,NN,O,test
US20160152624A1,CC(=O)C1CCOC1=O.NC(N)=O>>C/C(NC(N)=O)=C1\CCOC1=O,Cl,CCO,O,,,test
US20100048597A1,COc1cnccc1B(O)O.Clc1ccnc(Cl)n1>>COc1cnccc1-c1ccnc(Cl)n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US05521188,CC#N.COc1cncnc1N1CCNC(C)C1.Cc1ccc(S(=O)(=O)OCCCc2cn([Si](C(C)C)(C(C)C)C(C)C)c3ccc(-c4c(NC(C)(C)C)c(=O)c4=O)cc23)cc1>>CNc1c(-c2ccc3c(c2)c(CCCN2CCN(c4ncncc4OC)CC2)cn3[Si](C(C)C)(C(C)C)C(C)C)c(=O)c1=O.[NH4+].[OH-],,CC#N,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US04709093,CN.O=Cc1ccccc1>>NC=Cc1ccccc1,,Cc1ccccc1,,,,test
US20100261755A1,CCOC(=O)CC(=O)[C@H]1CCN(C(=O)OC)[C@@H](Cc2ccc(OC(F)(F)F)cc2)C1.NO>>COC(=O)N1CC[C@H](c2cc(=O)[nH]o2)C[C@@H]1Cc1ccc(OC(F)(F)F)cc1,,CO,O,Cl,[Na+].[OH-],test
US20120022066A1,COc1cccc([Mg]Br)c1.Clc1nc(Cl)nc(Cl)n1>>COc1cccc(-c2nc(Cl)nc(Cl)n2)c1,,C1CCOC1,ClC(Cl)Cl,O,O=C([O-])O.[Na+],test
US20030055035A1,C=COC(=O)Cl.O=C1CN(Cc2ccccc2)CC2=C1C(c1ccc(F)c(Br)c1)C1=C(CCCS1(=O)=O)N2>>C=COC(=O)N1CC(=O)C2=C(C1)NC1=C(C2c2ccc(F)c(Br)c2)S(=O)(=O)CCC1,,C1CCOC1,,,,test
US20050245530A1,NC(=O)c1cc(Cl)ccn1.O=C(CC(=O)Nc1ccc(Oc2ccnc(Cl)c2)c(F)c1)Nc1ccc(F)cc1>>NC(=O)c1cc(Oc2ccc(N)cc2F)ccn1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20070135477A1,C=O.CN1CCNCC1.O=C(Nc1c[nH]nc1-c1nc2cc(O)ccc2[nH]1)c1c(F)cccc1F>>CN1CCN(Cc2c(O)ccc3[nH]c(-c4n[nH]cc4NC(=O)c4c(F)cccc4F)nc23)CC1,,c1ccccc1,,,,test
US20100286191A1,CC(C)(C)c1cc(C(=O)Cl)cc2c1OCCC2(C)C.N>>CC(C)(C)c1cc(C(N)=O)cc2c1OCCC2(C)C,,C1COCCO1,,,,test
US20100298347A1,CCOC(=O)c1cc2cc(-c3ccc(OC(F)(F)F)cc3)ccc2c(O)c1F.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1cc2cc(-c3ccc(OC(F)(F)F)cc3)ccc2c(OS(=O)(=O)C(F)(F)F)c1F,,ClCCl,,c1ccncc1,,test
US20080027067A1,NC1Cc2ccccc2C1.O=C=NCCCl>>O=C(NCCCl)NC1Cc2ccccc2C1,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US04522742,COS(=O)(=O)c1ccccc1C.c1ccc(-c2cnc(-c3ccccc3)o2)cc1>>C[n+]1cc(-c2ccccc2)oc1-c1ccccc1.Cc1ccccc1S(=O)(=O)[O-],,CCOCC,,,,test
US20110152282A1,Cc1ccc(N)cc1B1OC(C)(C)C(C)(C)O1.Clc1cc2ccccc2cn1>>Cc1ccc(N)cc1-c1cc2ccccc2cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20120289501A1,Nc1ncnc2c1c(I)cn2C1CCC2(CC1)OCCO2>>Nc1ncnc2c1c(I)cn2C1CCC(=O)CC1,,CC(C)=O,O,O=C(O)C(=O)O,,test
US05958914,CCOC(=O)/C(=N\O)c1nc(N)sc1C.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)/C(=N\O)c1nc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)sc1C,,CN(C)C=O,,CCN(CC)CC,,test
US20110105564A1,CC(C)(C)OC(=O)Nc1ccsc1.II>>CC(C)(C)OC(=O)Nc1ccsc1I,,C1CCOC1,,[Cl-].[Na+],,test
US20140051676A1,CNc1cccc(C)c1.N#Cc1nc(N)nc(Cl)n1>>Cc1cccc(N(C)c2nc(N)nc(C#N)n2)c1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,CS(C)=O,test
US20100041634A1,O=[N+]([O-])c1ccc(N2CC3CCC3C2)nc1>>Nc1ccc(N2CC3CCC3C2)nc1,[Pd],,,,,test
US20110098302A1,CCOC(=O)Cc1ccc(OC)c(Oc2ccc(N3CCOCC3)cc2CN2CCOC2=O)c1>>COc1ccc(CC(=O)O)cc1Oc1ccc(N2CCOCC2)cc1CN1CCOC1=O,,O,,CO,[Li+].[OH-],test
US05256824,CC(C)(C)NC1C=CC(c2ccccc2)(c2ccccc2)C1.CS(=O)(=O)O>>CC(C)(C)NC1C=CC(c2ccccc2)(c2ccccc2)C1.CS(=O)(=O)O,,CCOC(C)=O,,,,test
US20110263626A1,C1CCNC1.O=Cc1ccc(Oc2cccc(C(=O)O)c2)cc1>>O=Cc1ccc(Oc2cccc(C(=O)N3CCCC3)c2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US04697012,O=C(OO)c1cccc(Cl)c1.c1ccc(Cc2nc(-c3ccncc3)cs2)cc1>>[O-][n+]1ccc(-c2csc(Cc3ccccc3)n2)cc1,,ClCCl,,,,test
US20060063812A1,CC(C)(C)OC(=O)Nc1ccc(CCCCn2ccnn2)cc1.FC(F)(F)Oc1ccc2[nH]c(-c3nc(CCl)co3)cc2c1>>CC(C)(C)OC(=O)N(Cc1coc(-c2cc3cc(OC(F)(F)F)ccc3[nH]2)n1)c1ccc(CCCCn2ccnn2)cc1,,CN(C)C=O,,,,test
US20130190330A1,COC(=O)CCl.O=c1[nH]nc(-c2ccc(Cl)cc2)n1CC(O)C(F)(F)F>>COC(=O)Cn1nc(-c2ccc(Cl)cc2)n(CC(O)C(F)(F)F)c1=O,,CC#N,,[I-].[K+],,test
US05968944,CCI.CCOC[C@H]1Cc2ccccc2CN1Cc1c(CC)nn(-c2c(C)cc(Br)cc2C)c1CC>>CCOC[C@H]1Cc2ccccc2CN1Cc1c(CC)nn(-c2c(C)cc(CC)cc2C)c1CC,,C1CCOC1,,[Li]CCCC,,test
US20150191461A1,FC(F)(F)c1ccnc(Cl)n1.Nc1cc(Br)cc([N+](=O)[O-])c1>>O=[N+]([O-])c1cc(Br)cc(Nc2nccc(C(F)(F)F)n2)c1,,C1COCCO1,,,,test
US20070066624A1,CC(C)(C)OC(=O)N1CCC(N[C@@H](CO)c2ccccc2)CC1.O=C=Nc1ccccc1>>CC(C)(C)OC(=O)N1CCC(N(C(=O)Nc2ccccc2)[C@@H](CO)c2ccccc2)CC1,,ClCCl,,,,test
US06875771B2,CSc1nc2ccccn2c(=N)c1S(=O)(=O)c1ccccc1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1nc2ccccn2c(=N)c1S(=O)(=O)c1ccccc1,,ClCCl,,,,test
US20150368238A1,CC(C)(C)OC(=O)N1CCCCC1(O)c1cc(F)ccc1F>>Fc1ccc(F)c(C2=NCCCC2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100152163A1,CC(=CBr)c1ccc(F)c(F)c1.CN1CCc2[nH]c3ccc(Cl)cc3c2CC1>>C/C(=C\n1c2c(c3cc(Cl)ccc31)CCN(C)CC2)c1ccc(F)c(F)c1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US04840953,CCOC(=O)c1cnc2c(S)cccn2c1=O.COC(=O)c1ccc(C(=O)Cl)cc1>>CCOC(=O)c1cnc2c(SC(=O)c3ccc(C(=O)OC)cc3)cccn2c1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05741811,CC(=O)OC(C#Cc1ccc(-c2cccs2)s1)COC1CCCCO1>>CC(=O)OC(C#Cc1ccc(-c2cccs2)s1)CO,,CO,,O=S(=O)(O)O,,test
US20140256700A1,COC(=O)c1ccc2c3c(C#N)cc(Br)cc3n(CC3CCOCC3)c2c1.OO>>COC(=O)c1ccc2c3c(C(N)=O)cc(Br)cc3n(CC3CCOCC3)c2c1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20030078251A1,CC(=O)Cl.COc1cccc([C@H]2O[C@H](CC(=O)Nc3ccsc3C(=O)O)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC>>COc1cccc([C@H]2O[C@H](CC(=O)Nc3ccsc3C(=O)O)C(=O)N(CC(C)(C)COC(C)=O)c3ccc(Cl)cc32)c1OC,,O,,CCOC(C)=O,c1ccncc1,test
US20060084681A1,NNc1ccc(OC(F)(F)F)cc1.O=CC(Cc1ccc(Br)cc1)C(=O)C1CCCCC1>>FC(F)(F)Oc1ccc(-n2ncc(Cc3ccc(Br)cc3)c2C2CCCCC2)cc1,,CO,,Cl,C[O-].[Na+],test
US20080081821A1,CCOC(=O)c1sc2cnccc2c1O.O=S(=O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>CCOC(=O)c1sc2cnccc2c1OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US04910211,COc1ccc(-c2nc3c(OC)cccc3s2)cc1>>COc1ccc(-c2nc3c(O)cccc3s2)cc1,,ClCCl,,BrB(Br)Br,,test
US20110263611A1,C[S@](=N)(=O)c1ccccc1.Nc1ncc(C(=O)O)cc1I>>C[S@@](=O)(=NC(=O)c1cnc(N)c(I)c1)c1ccccc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20010020112A1,CC(=O)CCC(C(=O)[O-])C(=O)c1ccc(C)cc1.CCOC(C)=O>>CCOC(=O)C1CCC(=O)C=C1c1ccc(C)cc1,,Cc1ccccc1,,C1CCNCC1,CC(=O)O,test
US04105520,C1CCCCC1.O=C(O)CCCCC(=O)O.O=[N+]([O-])O>>O=C(O)CCCCC(=O)O.O=[N+]([O-])C1CCCCC1,,C1CCCCC1,,,,test
US20130237555A1,O=C(O)c1cnccc1-c1ccc(Cl)cc1F>>O=c1oc2cc(Cl)ccc2c2ccncc12,,CS(C)=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090099178A1,CC1CCCCN1CCOc1ccc2cc(Br)ccc2c1.COB(OC)OC>>CC1CCCCN1CCOc1ccc2cc(B(O)O)ccc2c1,,C1CCOC1,O,[Li]CCCC,[Cl-].[NH4+],test
US20070270437A1,COC(=O)c1sc(-n2cnc3ccc(O)cc32)cc1O[C@H](C)c1ccccc1C(F)(F)F.Cc1ccc(S(=O)(=O)OC2CCN(C(=O)OC(C)(C)C)CC2)cc1>>COC(=O)c1sc(-n2cnc3ccc(OC4CCN(C(=O)OC(C)(C)C)CC4)cc32)cc1O[C@H](C)c1ccccc1C(F)(F)F,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US05418232,CC1(C)Oc2ccc(C(F)(F)C(F)(F)F)cc2C(O)C1Br>>CC1(C)Oc2ccc(C(F)(F)C(F)(F)F)cc2C2OC21,,CCOCC,,[K+].[OH-],,test
US20080039511A1,CCOC(=O)C(CC(=O)CBr)C(=O)c1ccccc1.CCOc1ccc(C(N)=S)cc1OCC>>CCOC(=O)C(Cc1csc(-c2ccc(OCC)c(OCC)c2)n1)C(=O)c1ccccc1,,CCO,,,,test
US20070254877A1,CC(C)(C)OC(=O)N1CCC2(CC1)CO2.Oc1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCC(O)(COc2ccc(F)cc2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120295884A1,CC(C)(C)OC(=O)NCc1cc(C=O)cc(Cl)c1F.CN1CCNCC1>>CN1CCN(Cc2cc(Cl)c(F)c(CNC(=O)OC(C)(C)C)c2)CC1,,C1CCOC1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05728835,Nc1ccc(C(=O)N(CCN2CCC(C(=O)c3ccc(F)cc3)CC2)c2cccnc2)cc1.O=C(O)C(F)(F)F>>O=C(c1ccc(F)cc1)C1CCN(CCN(C(=O)c2ccc(NC(=O)C(F)(F)F)cc2)c2cccnc2)CC1,,ClCCl,,c1ccncc1,O=C([O-])O.[Na+],test
US20140065103A1,CC(C)(C)OC(=O)N[C@@H]1C[C@H](C(=O)O)C1>>CC(C)(C)OC(=O)N[C@@H]1C[C@H](CO)C1,,C1CCOC1,,,,test
US20100249124A1,Cc1ccc(Oc2ccc(C#N)c(Cl)c2)cc1Cl.O=C1CCC(=O)N1Br>>N#Cc1ccc(Oc2ccc(CBr)c(Cl)c2)cc1Cl,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US04152442,CCCNc1nnc(C)o1.O=C(Cl)C1CCC1>>CCCN(C(=O)C1CCC1)c1nnc(C)o1,,c1ccccc1,,CCN(CC)CC,,test
US20140094465A1,O=C(O)c1ccc(-c2ccc(Br)s2)s1.OB(O)c1ccc(O)c(F)c1>>O=C(O)c1ccc(-c2ccc(-c3ccc(O)c(F)c3)s2)s1,,O,,,,test
US20130261178A1,OCCOCC1CC1.Oc1ccc(OCc2ccccc2)cc1>>c1ccc(COc2ccc(OCCOCC3CC3)cc2)cc1,,ClCCl,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130079323A1,CCc1[nH]c2nc(Sc3cnc4nccnc4c3)nc(N3CC(NC(=O)OC(C)(C)C)C3)c2c1Cl>>CCc1[nH]c2nc(Sc3cnc4nccnc4c3)nc(N3CC(N)C3)c2c1Cl,,CCOCC,,ClCCl,O=C(O)C(F)(F)F,test
US04623652,CC(=O)NCCN.O=C=Nc1ccccc1>>NCCNC(=O)Nc1ccccc1,,ClCCl,,,,test
US20020165201A1,CC(C)(C)OC(=O)CN.O=C(Cl)OCCl>>CC(C)(C)OC(=O)CNC(=O)OCCl,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20120116075A1,COC(=O)c1ccc(C)c(N)c1.O=C(Cl)C=Cc1cccnc1>>COC(=O)c1ccc(C)c(NC(=O)C=Cc2cccnc2)c1,,ClCCl,,CCN(CC)CC,Cl,test
US20110034507A1,COC(=O)c1coc(Cn2ccc3cc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)ccc32)n1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2c(ccn2Cc2nc(C(=O)O)co2)c1,,C1CCOC1,CO,[Na+].[OH-],,test
US20010001799A1,C1CCNC1.C=Cc1cc(C=O)cc(C(Nc2ccc(C#N)cc2)C(=O)OC)c1>>C=Cc1cc(CN2CCCC2)cc(C(Nc2ccc(C#N)cc2)C(=O)OC)c1,,CC(=O)O,CO,Cl,[Na],test
US20110077252A1,C=CCOc1cc(C(F)(F)F)nc(-c2ccc(N)cn2)n1.O=C(Cl)CCl>>C=CCOc1cc(C(F)(F)F)nc(-c2ccc(NC(=O)CCl)cn2)n1,,C1CCOC1,,CCN(CC)CC,,test
US20110015172A1,CC(C)(C)OC(=O)N1CCCC(N)C1.Clc1cc(I)cc(Cl)n1>>CC(C)(C)OC(=O)N1CCCC(Nc2cc(I)cc(Cl)n2)C1,,O,,,,test
US06217793B1,CCCCCCCC[C@H](C)C(=O)O.Oc1ccc(OCc2ccccc2)cc1>>CCCCCCCC[C@H](C)C(=O)Oc1ccc(OCc2ccccc2)cc1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05550147,CCOC(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(S(C)(=O)=O)cc2)cc1>>CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(CO)cc2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110083984A1,BrCc1ccccc1.COc1c(O)ccc(C=O)c1[N+](=O)[O-]>>COc1c(OCc2ccccc2)ccc(C=O)c1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030055261A1,CC(C)(C)OC(=O)N1CC(C=O)C1.CCOC(C)=O>>CCOC(=O)/C=C/C1CN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,Cl,CC(C)(C)[O-].[K+],test
US20090215858A1,FC(F)(F)c1cccc(N=C=S)c1.O=C1c2ccccc2CCCC1(CO)CO>>O=C1c2ccccc2CCCC1(CO)COC(=S)Nc1cccc(C(F)(F)F)c1,,C1CCOC1,,CCN(CC)CC,,test
US20050059705A1,COC(=O)C1Cc2c(OC)ccc(Br)c2C(CC2CCCC2)=N1>>COc1ccc(Br)c2c(CC3CCCC3)nc(C(=O)O)cc12,,C1CCOC1,CO,[Li+].[OH-],,test
US20100029643A1,CCNc1cc(C2CC2)ncc1NC(=O)C(C)NS(=O)(=O)c1ccc(C#N)nc1>>CCn1c(C(C)NS(=O)(=O)c2ccc(C#N)nc2)nc2cnc(C3CC3)cc21,,C1CCOC1,CO,,,test
US20050250753A1,CC(=O)OC(C)=O.Clc1ccc2c(c1)NCc1cc(Br)ccc1CO2>>CC(=O)N1Cc2cc(Br)ccc2COc2ccc(Cl)cc21,CN(C)c1ccncc1,Cc1ccccc1,,c1ccncc1,,test
US20130336920A1,NCc1cccc(C(F)(F)F)c1.O=[N+]([O-])c1ccc(N2CCCCC2)cc1-c1cc(F)ccn1>>O=[N+]([O-])c1ccc(N2CCCCC2)cc1-c1cc(NCc2cccc(C(F)(F)F)c2)ccn1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20040122039A1,CCC#Cc1ccccn1.Cc1cc(C)c(S(=O)(=O)ON)c(C)c1>>CCC#Cc1cccc[n+]1N.Cc1cc(C)c(S(=O)(=O)[O-])c(C)c1,,ClCCl,,CCOCC,,test
US20100048564A1,COC(=O)c1cccc(O)c1.Cn1c(CO)nc2ccc(Oc3cc(F)cc(F)c3)cc21>>COC(=O)c1cccc(OCc2nc3ccc(Oc4cc(F)cc(F)c4)cc3n2C)c1,,ClCCl,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US06218431B1,CCCC=Cc1c(C(C)C)nc(C(C)C)c(CO)c1-c1cccc(C)c1>>CCCCCc1c(C(C)C)nc(C(C)C)c(CO)c1-c1cccc(C)c1,,CCCCCC,CCOC(C)=O,,,test
US20040127538A1,CC(C)(C)OC(=O)n1nc(-c2cccc(F)c2)c2cc([N+](=O)[O-])ccc21>>CC(C)(C)OC(=O)n1nc(-c2cccc(F)c2)c2cc(N)ccc21,[Pd],C1CCOC1,,[H][H],,test
US20160115125A1,Cn1cc(S(=O)(=O)Cl)cc1C(=O)Cl.Nc1cc(Cl)c(F)c(Cl)c1>>Cn1cc(S(=O)(=O)Cl)cc1C(=O)Nc1cc(Cl)c(F)c(Cl)c1,,Cc1ccccc1,,,,test
US20110118245A1,CC#N.CCOC(=O)C(C)(F)F>>CC(F)(F)C(=O)CC#N,,C1CCOC1,,[H-].[Na+],,test
US20140179676A1,Cc1cc(O)ccc1C1SCCNc2c1c(-c1ccccn1)nn2C.OCc1cccnc1>>Cc1cc(OCc2cccnc2)ccc1C1SCCNc2c1c(-c1ccccn1)nn2C,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020115715A1,COc1ccc2c(c1)CC[C@H](NCCCCCCc1cc(N)cc(S(N)(=O)=O)c1F)[C@@H]2Cc1cccnc1.Cl.Cl.Cl>>Cl.Cl.Cl.Nc1cc(CCCCCCN[C@H]2CCc3cc(O)ccc3[C@H]2Cc2cccnc2)c(F)c(S(N)(=O)=O)c1,,ClCCl,,BrB(Br)Br,,test
US20140288025A1,COC(=O)C1=C[C@H](NC(=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)[C@@H](NC(C)=O)[C@H]([C@H](OC(C)=O)[C@@H](COC(C)=O)OC(C)=O)O1>>CC(=O)N[C@@H]1[C@@H](NC(=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)C=C(C(=O)O)O[C@H]1[C@H](OC(C)=O)[C@@H](COC(C)=O)OC(C)=O,,CO,,Cl,[Na+].[OH-],test
US05246948,O=C1CSC(=O)N1.O=Cc1ccccc1>>O=C1NC(=O)C(=Cc2ccccc2)S1,,CCO,,C1CCNCC1,,test
US20100093730A1,NO.O=C1CCC2CN(Cc3cccc(C(F)(F)F)c3)CC12>>ON=C1CCC2CN(Cc3cccc(C(F)(F)F)c3)CC12,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20140336224A1,COC(=O)c1ccccc1F.O=C(O)Cc1ccc(Cl)cc1F>>O=C(Cc1ccc(Cl)cc1F)c1ccccc1F,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20110039847A1,CC(C)(C)C(=O)CNC(=O)c1ccccc1[N+](=O)[O-]>>CC(C)(C)c1cnc(-c2ccccc2[N+](=O)[O-])o1,,O=P(Cl)(Cl)Cl,,,,test
US20120108583A1,CC1(C)Cc2c(c(C(=O)O)cc3nc(Nc4c(Cl)cncc4Cl)[nH]c23)O1.CCCCCN>>CCCCCNC(=O)c1cc2nc(Nc3c(Cl)cncc3Cl)[nH]c2c2c1OC(C)(C)C2,,C1CCOC1,CN(C)C=O,CN1CCOCC1,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US05985799,BrBr.Cc1ccc(C)c(SCCC(=O)O)c1>>Cc1cc(SCCC(=O)O)c(C)cc1Br,,ClCCl,,,,test
US20040106653A1,BrCc1ccccc1.O=C(NCCc1ccc(S(=O)(=O)c2ccc(O)c(O)c2)cc1)C(F)(F)F>>O=C(NCCc1ccc(S(=O)(=O)c2ccc(OCc3ccccc3)c(O)c2)cc1)C(F)(F)F,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100056553A1,C=CCC1(N)CCC(O)CC1.COc1ccc(Cn2ccc3cc(F)c(Cl)cc3c2=O)cc1>>C=CCC1(N)CCC(Oc2cc3ccn(Cc4ccc(OC)cc4)c(=O)c3cc2Cl)CC1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20130225524A1,CCOC(=O)c1cccc(Nc2c(C(N)=O)cnc3cc(-c4c(C)nn(C)c4C)ccc23)c1>>Cc1nn(C)c(C)c1-c1ccc2c(Nc3cccc(C(=O)O)c3)c(C(N)=O)cnc2c1,,CCO,,[Na+].[OH-],,test
US20140031355A1,CC(=O)OC(C)C#Cc1ccccc1C=O.NO>>CC(=O)OC(C)C#Cc1ccccc1/C=N\O,,CCO,,Cl,c1ccncc1,test
US04871842,CCOC(=O)[C@H](CCCCC1CCN(C(=O)OCc2ccccc2)CC1)N[C@@H](C)C(=O)N(CC(=O)OC(C)(C)C)C1Cc2ccccc2C1>>C[C@H](N[C@@H](CCCCC1CCN(C(=O)OCc2ccccc2)CC1)C(=O)O)C(=O)N(CC(=O)OC(C)(C)C)C1Cc2ccccc2C1,,CO,,O,[Na+].[OH-],test
US20100076026A1,COC(=O)C(C)(C)c1ccc(N)c(F)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COC(=O)C(C)(C)c1ccc(N=C=O)c(F)c1,,ClCCl,,CCN(CC)CC,,test
US20040209865A1,O=[N+]([O-])c1ccc2[nH]c(CN3CCCC3)nc2c1>>Nc1ccc2[nH]c(CN3CCCC3)nc2c1,[Ni],CO,,,,test
US04261990,N#CCCl.c1ccc(C(OC2CCNCC2)c2ccccc2)cc1>>N#CCN1CCC(OC(c2ccccc2)c2ccccc2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110152326A1,CC(C)(c1c(F)cc(O)cc1F)C(F)(F)F.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(c1c(F)cc(OS(=O)(=O)C(F)(F)F)cc1F)C(F)(F)F,CN(C)c1ccncc1,CCOC(C)=O,,ClCCl,c1ccncc1,test
US04251263,O=C(O)c1cccnc1Cl.Oc1cccc(C(F)(F)F)c1>>O=C(O)c1cccnc1Oc1cccc(C(F)(F)F)c1,,CO,,C[O-].[Na+],,test
US20040106639A1,CC(=O)c1ccc2c(c1)C(=CCCBr)c1cccnc1CO2.CC1(C)CNCC[C@]1(O)c1ccc(Cl)cc1>>CC(=O)c1ccc2c(c1)C(=CCCN1CC[C@](O)(c3ccc(Cl)cc3)C(C)(C)C1)c1cccnc1CO2,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US06340687B1,C=CCN1CCCN(c2c(C)cccc2Cl)C1=S.CC(C)CN>>Cc1cccc(Cl)c1NCCCNCC(C)C,,O,,,,test
US20050233988A1,CC(=O)OC[C@H]1O[C@@H](n2cc(CBr)nn2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.CCCC[Sn](CCCC)(CCCC)c1ccc(CC)cc1>>CCc1ccc(Cc2cn([C@@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)nn2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,CCOC(C)=O,[F-].[K+],,test
US20050085512A1,O=C(O)c1ccc(-c2ncccc2Cl)cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Nc1ccc(-c2ncccc2Cl)cc1,,CN(C)C=O,O,CCN(CC)CC,,test
US20060094767A1,C[C@@]1(Cn2cc([N+](=O)[O-])nc2Cl)CO1.c1ccc2c(c1)CCCN2>>C[C@](O)(CN1CCCc2ccccc21)Cn1cc([N+](=O)[O-])nc1Cl,,O,,CN(C)C=O,,test
US04472433,CCOC(=O)Cc1cccc(Oc2ccccc2Cl)c1N>>Nc1c(CC(=O)O)cccc1Oc1ccccc1Cl,,O,,[Na+].[OH-],,test
US20130210844A1,CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)O)c1F.Cc1nc(NC2CCC(F)(F)CC2)c2cccc(N)c2n1>>Cc1nc(NC2CCC(F)(F)CC2)c2cccc(NC(=O)c3c(Cl)ccc(CNC(=O)C(C)(C)C)c3F)c2n1,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20080004289A1,O=C(c1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1>>OC(c1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1,,CO,O,[BH4-].[Na+],,test
US05804601,COc1ccc(C(O)CCCCC(=O)O)cc1.Oc1ccc(O)c2ccccc12>>COc1ccc(C(CCCCC(=O)O)C2=CC(=O)c3ccccc3C2=O)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04335126,COc1cc(O)cc(OC)c1OC.ClCC1CO1.[OH-]>>COc1cc(OOCC2CO2)cc(OC)c1OC,,Cc1ccccc1,,O,,test
US20040006067A1,CC(C)(C)OC(=O)N1CCC(c2ccccc2N(CCN2C(=O)c3ccccc3C2=O)S(C)(=O)=O)CC1.Cl>>CS(=O)(=O)N(CCN1C(=O)c2ccccc2C1=O)c1ccccc1C1CCNCC1.Cl,,CCOC(C)=O,,,,test
US05731331,Clc1cn[nH]c1.OC1(c2ccccc2)CC[N+]2(CCCC2)CC1>>OC1(c2ccccc2)CCN(CCCCn2cc(Cl)cn2)CC1,,CCOCC,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US05206327,B.C1=CCCCC1.C1=CCCCC1>>B(C1CCCCC1)C1CCCCC1,,C1CCOC1,,,,test
US20160176850A1,C[Si](C)(C)CCOCCl.Ic1n[nH]c2ncccc12>>C[Si](C)(C)CCOCn1nc(I)c2cccnc21,,CN(C)C=O,,O,[H-].[Na+],test
US04766131,COc1cc2c(cc1OC)C(C)NCC2.O=C(O)Cc1cccc([N+](=O)[O-])c1>>COc1cc2c(cc1OC)C(C)N(C(=O)Cc1cccc([N+](=O)[O-])c1)CC2,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20040014968A1,COCSc1ccc(CC(=O)OC)cc1>>COCSc1ccc(CC(=O)O)cc1,,CO,O,C1CCOC1,[Li+].[OH-],test
US05321082,C#CC(C)(C)O.C=C(C)C(=O)Cl>>C#CC(C)(C)OC(=O)C(=C)C,,c1ccncc1,,c1ccccc1,,test
US04816470,O=[N+]([O-])c1ccc(CS(=O)(=O)NC2CCCCC2)cc1>>Nc1ccc(CS(=O)(=O)NC2CCCCC2)cc1,,CC(C)O,,,,test
US20090264403A1,CS(=O)(=O)OC[C@H]1CCCO1.O=C1CCc2cc(O)ccc21>>O=C1CCc2cc(OC[C@H]3CCCO3)ccc21,,CN(C)C=O,,O,,test
US20060160803A1,Nc1cc(/C=C/N2C(=O)c3ccccc3C2=O)cc(C(F)(F)F)c1>>Nc1cc(CCN2C(=O)c3ccccc3C2=O)cc(C(F)(F)F)c1,[Pd],C1CCOC1,CCO,,,test
US06177132B1,N#Cc1cccc([N+](=O)[O-])c1C#N.Oc1ccccc1C(F)(F)F>>N#Cc1cccc(Oc2ccccc2C(F)(F)F)c1C#N,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US04611056,Cc1c2sc3ccccc3nc-2c2ccccc2c1=O>>Cc1c2c(c3ccccc3c1O)Nc1ccccc1S2,,CCOC(C)=O,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20130065881A1,Clc1nnc(NCC2CC2)c2c1OCCO2.NNC(=O)c1cccc(OC(F)(F)F)c1>>FC(F)(F)Oc1cccc(-c2nnc3c4c(c(NCC5CC5)nn23)OCCO4)c1,,CCCCO,,CCOC(C)=O,O=C([O-])O.[Na+],test
US04010177,C1CCNC1.ClCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2>>Clc1ccc2c(c1)C(c1ccccc1)=NCc1nnc(CN3CCCC3)n1-2,,C1CCOC1,,[I-].[K+],,test
US05834157,Cc1ccc(C)c(-c2c3ccccc3nc3ccc(N)cc23)c1.O=C(Cl)c1ccccc1>>Cc1ccc(C)c(-c2c3ccccc3nc3ccc(NC(=O)c4ccccc4)cc23)c1,,ClCCl,,,,test
US20110183998A1,c1ccc(COc2ccc(OC3COC(c4ccccc4)OC3)nc2)cc1>>OCC(CO)Oc1ccc(OCc2ccccc2)cn1,,CO,,Cl,,test
US04389403,Clc1cccc(Cl)c1NC1=NCCN1.O=C(O)c1ccc(O)nc1>>O=C(c1ccc(O)nc1)N1CCN=C1Nc1c(Cl)cccc1Cl,,C1CCOC1,CN(C)P(=O)(N(C)C)N(C)C,O=C([O-])O.[Na+],,test
US20120071478A1,CNCc1ccccc1.Clc1ccc2nc(Cl)cnc2c1>>CN(Cc1ccccc1)c1cnc2cc(Cl)ccc2n1,,CS(C)=O,,O,,test
US20080096861A1,CC(C)(C)OC(=O)N1CCC(n2c(CNC(=O)OCc3ccccc3)nc3ccccc32)CC1>>CC(C)(C)OC(=O)N1CCC(n2c(CN)nc3ccccc32)CC1,[Pd],CO,,,,test
US20110213143A1,CCOC(C)=O.CN(C)C=O.COc1ccc(CCl)cc1.Cc1ccnc(N)c1.O=C(O)CC(O)(CC(=O)O)C(=O)O>>COc1ccc(CN(Cc2ccc(OC)cc2)c2cc(C)ccn2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20030166650A1,C[C@H](NC(=O)OC(C)(C)C)c1cccc(N2CCN(C)CC2)c1>>C[C@H](N)c1cccc(N2CCN(C)CC2)c1,,C1COCCO1,,Cl,,test
US05512575,Brc1cccnc1.O=C1CCN(CC23CC(c4ccccc42)c2ccc(Cl)cc23)CC1>>OC1(c2cccnc2)CCN(CC23CC(c4ccccc42)c2ccc(Cl)cc23)CC1,,C1CCOC1,,[Li]CCCC,,test
US05750576,ClC(Cl)(Cl)Cl.OCC/C(=C(\c1ccccc1)c1ccc(OCCOCc2ccccc2)cc1)c1ccccc1>>ClCC/C(=C(\c1ccccc1)c1ccc(OCCOCc2ccccc2)cc1)c1ccccc1,,CC#N,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20130102584A1,COC(=O)c1ccc(Nc2ccc(F)cc2)c(N)c1.COC(OC)OC>>COC(=O)c1ccc2c(c1)ncn2-c1ccc(F)cc1,,CN(C)C=O,,O,,test
US20140005213A1,CC(C)(C)OC(=O)N(CCF)[C@H]1CCNC1.O=S(=O)(O[C@@H](c1ccc(Cl)nc1)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N(CCF)[C@H]1CCN([C@H](c2ccc(Cl)nc2)C(F)(F)F)C1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20020147188A1,CC(C)C[C@H](N)C(=O)NC1CCCN(S(=O)(=O)c2ccccn2)CC1O.O=S(=O)(Cl)c1ccccn1>>CC(C)C[C@H](NS(=O)(=O)c1ccccn1)C(=O)NC1CCCN(S(=O)(=O)c2ccccn2)CC1O,,ClCCl,,CCN(CC)CC,CO,test
US20130053341A1,CC(=O)O.Nc1nc(-c2cccnc2)nc2ccc(Br)cc12>>CC(=O)Nc1nc(-c2cccnc2)nc2ccc(Br)cc12,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20090306078A1,COC(=O)c1ccnc(NC(=O)COc2ccc(Cl)cc2Cl)c1>>O=C(COc1ccc(Cl)cc1Cl)Nc1cc(C(=O)O)ccn1,,c1ccncc1,,[I-].[Li+],,test
US06544976B1,CCC(C)(C)[Mg]Cl.COC(=O)C(=O)N1CC[C@H]1c1nnnn1CCCc1cccnc1>>CCC(C)(C)C(=O)C(=O)N1CC[C@H]1c1nnnn1CCCc1cccnc1,,C1CCOC1,ClCCl,CO,[Cl-].[NH4+],test
US20030069257A1,Brc1nccs1.CCCC[Sn](CCCC)(CCCC)c1nccn1COCC>>CCOCn1ccnc1-c1nccs1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US20150105317A1,O=C(CCCCC(=O)ON1C(=O)CCC1=O)OCc1ccccc1.OCCCNCCCO>>O=C(CCCCC(=O)N(CCCO)CCCO)OCc1ccccc1,,CN(C)C=O,,,,test
US03968228,CC(=O)OCc1nc([N+](=O)[O-])c(C#N)n1C>>Cn1c(CO)nc([N+](=O)[O-])c1C#N,,CO,,N,,test
US07078403B1,Clc1ccnnc1Cl.NCCCCCO>>OCCCCCNc1ccc(Cl)nn1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20040106606A1,Fc1ccc(Br)c(CBr)c1.O>>OCc1cc(F)ccc1Br,,C1COCCO1,O,O=C([O-])[O-].[Ca+2],,test
US04578392,CC=Cc1c(C(C)C)nn2ccccc12>>CCCc1c(C(C)C)nn2ccccc12,[Pd],CCO,,[H][H],,test
US05152824,CNOC.CNS(=O)(=O)Cl>>CNS(=O)(=O)N(C)OC,,ClCCl,,CCN(CC)CC,Cl,test
US05756532,Cc1ccc(S(=O)(=O)OC[C@H]2COc3cc(C)c4c(c3O2)CC(=O)N4)cc1.NCc1cccs1>>Cc1cc2c(c3c1NC(=O)C3)OC(CNCc1cccs1)CO2,,CS(C)=O,,O,,test
US20100087496A1,O=C(Cl)C(=O)Cl.O=C(O)C=Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>O=C(Cl)C=Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1,CN(C)C=O,,,,,test
US20120115848A1,CC[C@@H]1c2nncn2-c2cnc(-c3ccncc3)nc2N1C1CCCC1.O=C(OO)c1cccc(Cl)c1>>CC[C@@H]1c2nncn2-c2cnc(-c3cc[n+]([O-])cc3)nc2N1C1CCCC1,,ClCCl,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US05468733,CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)CCCCl)C(C)C)C(=O)N[C@@H](CCSC)C(=O)OC>>CC[C@H](C)[C@H](NC(=O)[C@H](C(C)C)N1CCCC1=O)C(=O)N[C@@H](CCSC)C(=O)O,,CO,,[Na+].[OH-],,test
US06180627B2,CC(C)(C)OC(=O)N1CCC[C@@H]1CN=[N+]=[N-]>>CC(C)(C)OC(=O)N1CCC[C@@H]1CN.N,[Pd],CCO,,,,test
US20130090390A1,CC(C)c1ccc(O)cc1>>CC(C)C1CCC(O)CC1,[Ru],CCO,,[H][H],,test
US20100137281A1,CC(C)(C)C(=O)CBr.CCCOc1cc(=O)[nH]c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1>>CCCOc1cc(=O)n(CC(=O)C(C)(C)C)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1,,CCOC(C)=O,,CN(C)C=O,[H-].[Na+],test
US20100041673A1,CN1CCN(C(=O)c2ccc3[nH]ccc3c2)CC1>>CN1CCN(Cc2ccc3[nH]ccc3c2)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130252941A1,CN.Clc1cc(Nc2nccc3nn(-c4c(Cl)cccc4Cl)cc23)ncn1>>CNc1cc(Nc2nccc3nn(-c4c(Cl)cccc4Cl)cc23)ncn1,,CN1CCCC1=O,,,,test
US04230628,COC(=O)CCCCCCCCCCCCCCCN(C(=O)OCc1ccccc1)c1ccc(C(=O)Cl)cc1.O=C(O)CC(O)C(=O)O>>COC(=O)CCCCCCCCCCCCCCCNc1ccc(C(=O)OC(=O)C(O)CC(=O)O)cc1,[Pd],C1CCOC1,CCOCC,CCN(CC)CC,[H][H],test
US20140121198A1,CC(C)(C)OC(=O)NC1CCC(N)CC1.O=[N+]([O-])c1cnc2ccsc2c1Cl>>CC(C)(C)OC(=O)NC1CCC(Nc2c([N+](=O)[O-])cnc3ccsc23)CC1,,CC(C)O,,CCN(CC)CC,,test
US20110172237A1,Cc1ccc(NC(=O)CBr)cc1.O=C(O[C@H]1CN2CCC1CC2)C1(c2ccccc2)CCCCCC1>>Cc1ccc(NC(=O)C[N+]23CCC(CC2)[C@@H](OC(=O)C2(c4ccccc4)CCCCCC2)C3)cc1.[Br-],,CC#N,,,,test
US04831055,COC(=O)c1ccc(OCCNC(=O)c2ccc(Cl)cc2)cc1>>O=C(O)c1ccc(OCCNC(=O)c2ccc(Cl)cc2)cc1,,CCO,O,[Na+].[OH-],,test
US20080103142A1,COC(=O)[C@@H]1CC[C@@H](N)CC1.Clc1ncc(Cl)c(-n2nnc3ccccc32)n1>>COC(=O)C1CCC(Nc2ncc(Cl)c(-n3nnc4ccccc43)n2)CC1,,C1CCOC1,,,,test
US20140364432A1,C[C@@H]1CCCN[C@@H]1CN1C(=O)c2ccccc2C1=O.O=C(O)c1c(F)cccc1I>>C[C@@H]1CCCN(C(=O)c2c(F)cccc2I)[C@@H]1CN1C(=O)c2ccccc2C1=O,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080070928A1,CC(C)(C)OC(=O)N1CCCC1c1cc(N)c(N)cc1Oc1ccc(S(C)(=O)=O)cc1.O=Cc1cc[nH]n1>>CC(C)(C)OC(=O)N1CCCC1c1cc2[nH]c(-c3cc[nH]n3)nc2cc1Oc1ccc(S(C)(=O)=O)cc1,,CCOC(C)=O,,CN(C)C=O,,test
US20160108027A1,COC(=O)[C@@H]1C[C@@H](OC2CC2)CN1.COc1cc(C(=O)O)cc2nc(NCc3cc(Cl)ccn3)oc12>>COC(=O)[C@@H]1C[C@@H](OC2CC2)CN1C(=O)c1cc(OC)c2oc(NCc3cc(Cl)ccn3)nc2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06093732,CCOC(=O)c1cnc2cc([N+](=O)[O-])ccc2c1O.NCc1ccc(Cl)cc1>>Nc1ccc2c(O)c(C(=O)NCc3ccc(Cl)cc3)cnc2c1,,CCOC(C)=O,,,,test
US05084084,C#CCN1C(=O)COc2cc(F)c(-n3c(=O)cc(C(F)(F)F)[nH]c3=O)cc21.COS(=O)(=O)OC>>C#CCN1C(=O)COc2cc(F)c(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20150203468A1,CCOC(=O)[C@H]1[C@H](c2cnc(Br)s2)[C@H]1c1ccccc1.OB(O)c1ccc(F)cc1>>CCOC(=O)[C@H]1[C@H](c2cnc(-c3ccc(F)cc3)s2)[C@H]1c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20100016319A1,C1COCCN1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(F)cc(C)c2Oc2ccnc(Cl)n2)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(F)cc(C)c2Oc2ccnc(N3CCOCC3)n2)cc1,,CCO,,O=C(O)CC(O)(CC(=O)O)C(=O)O,,test
US04083983,CCOc1cccnc1CO.O=S(Cl)Cl>>CCOc1cccnc1CCl.Cl,,ClC(Cl)Cl,,,,test
US04613598,NC(=O)c1cc(C(=O)CCCCl)ccc1OCc1ccccc1.O.c1ccc(N2CCNCC2)cc1>>NC(=O)C1C=C(C(=O)CCCN2CCN(c3ccccc3)CC2)C=CC1(O)OCc1ccccc1,,O,,CCN(CC)CC,CS(C)=O,test
US05041462,CC(=O)OCC(=O)Cl.CCN(CC)c1cccc(N)c1C#N>>CCN(CC)c1cccc(NC(=O)COC(C)=O)c1C#N,,ClCCl,,O,c1ccncc1,test
US20090156592A1,CCOC(=O)CI.FC(F)(F)c1cc(Br)[nH]n1>>CCOC(=O)Cn1nc(C(F)(F)F)cc1Br,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04153619,O=C(O)CC1(Br)OC2=CC=CC2=CC1c1ccccc1.O=[N+]([O-])[N+](=O)[O-]>>O=C(O)CC1([N+](=O)[O-])OC2=CC=CC2=CC1c1ccccc1,,ClC(Cl)Cl,,C1=CCCCC1,,test
US20090143353A1,CN(C)[C@H]1CCNC1.CNC(=O)c1nc2c(C#N)c(C)c(-c3ccccc3)c(F)c2o1>>CNC(=O)c1nc2c(C#N)c(C)c(-c3ccccc3)c(N3CC[C@H](N(C)C)C3)c2o1,,CS(C)=O,,CCN(CC)CC,,test
US20090163508A1,CC(C)(C)OC(=O)N1CCN(c2ccnc(Cl)n2)CC1.OB(O)Oc1cccc(F)c1F>>CC(C)(C)OC(=O)N1CCN(c2ccnc(-c3cccc(F)c3F)n2)CC1,,O,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20030176418A1,CCCCCC1CC2CCC(C1)N2.C[C@H](CI)CN1C(=O)COc2cc(F)ccc21>>CCCCCC1CC2CCC(C1)N2C[C@@H](C)CN1C(=O)COc2cc(F)ccc21,,CCCCCCC,CCOC(C)=O,,,test
US20040029932A1,COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cccc(C#N)c1)C(F)(F)F.OO>>COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cccc(C(N)=O)c1)C(F)(F)F,,CCO,O,Cl,[K+].[OH-],test
US20120122780A1,S=C=Nc1cccc2ccccc12.[N-]=[N+]=[N-]>>Sc1nnnn1-c1cccc2ccccc12,,CCO,,Cl,,test
US05238832,C#CCOC1CCCCO1.CCCCCCCCBr>>CCCCCCCCC#CCOC1CCCCO1,,C1CCOC1,,[Li]CCCC,,test
US20110039843A1,Fc1cnccc1-c1nc2cc(C(F)(F)F)ccc2o1.OCC(F)(F)F>>FC(F)(F)COc1cnccc1-c1nc2cc(C(F)(F)F)ccc2o1,,O,,CN(C)C=O,[H-].[Na+],test
US04474754,Cc1ccc(S(=O)(=O)NCCCC[C@H](NC(=O)OCc2ccccc2)C(=O)N[C@@H](CCC(=O)OCc2ccccc2)C(=O)OCc2ccccc2)cc1>>Cc1ccc(S(=O)(=O)NCCCC[C@H](N)C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1,[Pd],CC(=O)O,CO,O,,test
US20110257189A1,COc1ccc(Cn2cc(Cc3ccc([N+](=O)[O-])cc3)n3cc(-c4cn(S(=O)(=O)c5ccccc5)c5ncccc45)cc3c2=O)c(OC)c1>>COc1ccc(Cn2cc(Cc3ccc(N)cc3)n3cc(-c4cn(S(=O)(=O)c5ccccc5)c5ncccc45)cc3c2=O)c(OC)c1,[Pd],CO,ClCCl,,,test
US06878706B1,CC(C)CN.O=C(CBr)N1CCOCC1>>CC(C)CNCC(=O)N1CCOCC1,,C1CCOC1,,,,test
US20100168418A1,CNC(=O)COc1cccc2c1ccc(=O)n2CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1.Cl>>CNC(=O)COc1cccc2c1ccc(=O)n2CCN1CCC(NCc2ccc3c(c2)OCCO3)CC1.Cl,,CCOC(C)=O,,,,test
US05444129,C=Cc1ccc(N)cc1.Cc1cccc(N=C=O)c1.Cc1cccc(NC(N)=O)c1>>C=Cc1ccccc1.Cc1ccccc1NC(N)=O,,ClC(Cl)Cl,,,,test
US20110311474A1,CC[C@@H]1C[C@@H](O)C[C@@H]1c1nnc2cnc3c(ccn3COCC[Si](C)(C)C)n12.CS(=O)(=O)Cl>>CCC1CC(OS(C)(=O)=O)CC1c1nnc2cnc3c(ccn3COCC[Si](C)(C)C)n12,,ClCCl,,,,test
US05212320,CC(C)Cc1ccccc1.CCCCCC(=O)Cl>>CCCCCC(=O)c1ccc(CC(C)C)cc1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20130338124A1,CC(C)CI.Cn1c(=O)[nH]c2nn(Cc3ccc(-c4cccc(F)n4)cc3)cc2c1=O>>CC(C)Cn1c(=O)n(C)c(=O)c2cn(Cc3ccc(-c4cccc(F)n4)cc3)nc21,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140235660A1,COC(=O)/C=C/c1ccc(Oc2c(-c3ccc(OC)cc3)sc3cc(OC)ccc23)cc1>>COC(=O)/C=C/c1ccc(Oc2c(-c3ccc(O)cc3)sc3cc(O)ccc23)cc1,,ClCCl,,BrB(Br)Br,,test
US20070185324A1,CC(=O)Nc1c(C)ccc(C(=O)O)c1[N+](=O)[O-]>>Cc1ccc(C(=O)O)c([N+](=O)[O-])c1N,,C1COCCO1,,Cl,,test
US20110224254A1,COC1=C(C)C(c2cccc(F)c2F)N(c2ccc3nc[nH]c3c2)C1=O>>COC1=C(C)[C@@H](c2cccc(F)c2F)N(c2ccc3nc[nH]c3c2)C1=O,,CO,,C,O=C[O-].[NH4+],test
US04454120,N[C@H](CO)C(=O)NCCCc1ccccc1.O=C(N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)Oc1c(F)c(F)c(F)c(F)c1F)OCc1ccccc1>>O=C(N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@H](CO)C(=O)NCCCc1ccccc1)OCc1ccccc1,,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US20130034616A1,O=C(Nc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ncc(Br)nc12)c1ccccc1CBr>>O=C1c2ccccc2CN1c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ncc(Br)nc12,,CN(C)C=O,,[H-].[Na+],,test
US20040110767A1,C1CCNCC1.Cc1cc(C)c(S(=O)(=O)N(Cc2ccc(O)cc2Cl)c2ccc(CCC=O)cc2)c(C)c1>>Cc1cc(C)c(S(=O)(=O)N(Cc2ccc(O)cc2Cl)c2ccc(CCCN3CCCCC3)cc2)c(C)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US07001917B2,Cc1ccc(S(=O)(=O)N=C=O)cc1.OCCc1ccc(-n2nc(C(F)(F)F)cc2-c2ccccc2)cc1>>Cc1ccc(S(=O)(=O)NC(=O)OCCc2ccc(-n3nc(C(F)(F)F)cc3-c3ccccc3)cc2)cc1,,ClCCl,,,,test
US20130244958A1,CC(Cl)OC(=O)Cl.COCCOCCOCCOCCOCCOCCO>>COCCOCCOCCOCCOCCOCCOC(=O)OC(C)Cl,,ClCCl,,c1ccncc1,,test
US04458078,CC(C)COC(=O)Cl.C[Si](C)(C)C(C(N)=O)[Si](C)(C)C.NCC(=O)O.N[C@@H](CCC[C@@H](N)C(=O)O)C(=O)O>>C[C@@H](NC(=O)OC(C)(C)C)C(=O)ON1C(=O)CCC1=O,,CN(C)C=O,ClCCl,CN1CCOCC1,,test
US03931235,Cc1cc(O)c(SCc2ccc(Cl)cc2)c(=O)o1.OO>>Cc1cc(O)c(S(=O)Cc2ccc(Cl)cc2)c(=O)o1,,CC(=O)O,,,,test
US04228170,ClCCl.Sc1ccc2ccncc2c1Cl>>Cl.Sc1ccc2c(c1Cl)CNCC2,,CO,,,,test
US20080161328A1,Cc1nc2cccc([N+](=O)[O-])c2c(=O)o1.NC1CCC(=O)NC1=O>>Cc1nc2cccc([N+](=O)[O-])c2c(=O)n1C1CCC(=O)NC1=O,,c1ccncc1,,CO,Cl,test
US03951978,O=C(c1ccc(F)cc1)C(Br)CCCl.Oc1cccc2ccccc12>>O=C(c1ccc(F)cc1)C(CCCl)Oc1cccc2ccccc12,,CC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US05364866,ClCCCOc1ccccc1.Fc1ccc2c(C3CCNCC3)noc2c1>>Fc1ccc2c(C3CCN(CCCOc4ccccc4)CC3)noc2c1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20090143380A1,COC(=O)OC.O=C1CCc2cc(Cl)ccc2C1>>COC(=O)C1=C(O)CCc2cc(Cl)ccc21,,Cc1ccccc1,O,CC(=O)O,[H-].[Na+],test
US05057524,CNC(=O)CCCl.OC(c1ccc(F)cc1)(c1ccc(F)cc1)C1CCNCC1>>CNC(=O)CCN1CCC(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)CC1,,CN(C)C=O,O,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US20050250749A1,COCCOCCC[C@]12CCC3=C(CCc4cc(OC)ccc43)[C@@H]1CCC2=O>>COCCOCCC[C@]12CCC3=C(CCc4cc(OC)ccc43)[C@@H]1CCC2O,,CO,,[BH4-].[Na+],,test
US20140051679A1,C=O.CC1(C)OB(c2ccc(NC3CCOCC3)cc2)OC1(C)C>>CN(c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)C1CCOCC1,,CO,ClCCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05750545,Nc1nc[nH]n1.OCCCCCN=C=S>>Nc1ncnn1C(=S)NCCCCCO,,CO,ClC(Cl)Cl,CN(C)C=O,,test
US20100069418A1,Cc1nc2sccn2c1C(=O)N[C@@H]1CCCN(C(=O)O)C1>>Cc1nc2sccn2c1C(=O)N[C@@H]1CCCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130029990A1,COCC(=O)Nc1cc(Oc2ccc([N+](=O)[O-])c(F)c2)ccn1>>COCC(=O)Nc1cc(Oc2ccc(N)c(F)c2)ccn1,[Fe],CC(=O)O,,O=C([O-])O.[Na+],,test
US20070124152A1,CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN2C(=O)c3ccccc3C2=O)c1=O.NCCOCCO>>O=C(NCCOCCO)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN2C(=O)c3ccccc3C2=O)c1=O,,CCO,,,,test
US20140045819A1,O=C1CCC(=O)N1Br.O=C1CCCc2ccccc2N1>>O=C1CCCc2cc(Br)ccc2N1,,CCOC(C)=O,CN(C)C=O,,,test
US20040133008A1,[N-]=[N+]=NCCn1nccc1NC(c1ccccc1)(c1ccccc1)c1ccccc1>>NCCn1nccc1NC(c1ccccc1)(c1ccccc1)c1ccccc1,[Pd],CO,,[H][H],,test
US20050148604A1,CN1CCNCC1.COc1cc(C=O)ccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1>>COc1cc(CN2CCN(C)CC2)ccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1,,CC(=O)O,ClCCCl,O=C([O-])O.[Na+],,test
US20070232649A1,COc1cc(O)c(C=O)c(OC)c1.COc1ccc(CS(=O)(=O)CC(=O)O)cc1>>COc1ccc(CS(=O)(=O)c2cc3c(OC)cc(OC)cc3oc2=O)cc1,,CC(=O)O,,,,test
US20130237525A1,COc1ccc([N+](=O)[O-])c(O)c1C1CCCC(=O)N1Cc1ccc2ccccc2n1>>COc1ccc(N)c(O)c1C1CCCC(=O)N1Cc1ccc2ccccc2n1,,CO,,,,test
US20150051199A1,CC(C)(C)[S@@](=O)/N=C/c1ccc(Cl)cc1F.CC[Mg]Br>>CC[C@@H](N[S@](=O)C(C)(C)C)c1ccc(Cl)cc1F,,C1CCOC1,O,CCOCC,[Cl-].[NH4+],test
US20100076026A1,CC(C)(C)OC(=O)CCc1ccc(NC(=O)N(c2c3ccccc3nn2-c2ccc(Cl)cc2)C2CCCCC2)c(F)c1>>O=C(O)CCc1ccc(NC(=O)N(c2c3ccccc3nn2-c2ccc(Cl)cc2)C2CCCCC2)c(F)c1,,C1COCCO1,Cl,,,test
US20140288090A1,CC(C)(C)OC(=O)c1ccccc1-c1ccc(CBr)cc1.COC(=O)c1ccc2[nH]nc(Br)c2c1>>COC(=O)c1ccc2c(c1)c(Br)nn2Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20080039456A1,CCOC(=O)CCCN1C(=O)CNC1=S.CCOC(=O)c1cc(-c2ccc(Cl)cc2)oc1C=O>>CCOC(=O)CCCN1C(=O)c2cc3oc(-c4ccc(Cl)cc4)cc3c(=O)n2C1=S,,C1CCOC1,CCCCCC,CCOC(C)=O,[H-].[Na+],test
US04081441,NN.NNC(=O)c1n[nH]c(=O)[nH]c1=O.O.O=N[O-]>>O=C(O)c1n[nH]c(=O)[nH]c1=O.[N-]=[N+]=[N-],,CN(C)C=O,O,Cl,,test
US20110046372A1,CC(=O)OC(C)=O.Nc1ccccc1C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>O=c1cc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccccc2[nH]1,,Cc1ccccc1,,O,CC(C)(C)[O-].[K+],test
US05444074,CN(C)C(N)=O.O=C(Cl)SCl>>CN(C)c1nsc(=O)o1,,CC#N,,,,test
US20100286210A1,Cc1oc(-c2ccccc2)[n+]([O-])c1C.O=P(Cl)(Cl)Cl>>Cc1oc(-c2ccccc2)nc1CCl,,ClC(Cl)Cl,,,,test
US20060100213A1,O=Cc1ccc2c(c1)CCC[C@@H]2O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>[N-]=[N+]=N[C@@H]1CCCc2cc(C=O)ccc21,,Cc1ccccc1,,C1CCC2=NCCCN2CC1,,test
US20040242578A1,Cn1nc2cc([N+](=O)[O-])ccc2c1CBr.O>>Cn1nc2cc([N+](=O)[O-])ccc2c1CO,,CC#N,O,[Na+].[OH-],,test
US20120220665A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC(c1ccccc1)C(O)c1ccc(Br)cc1>>CC(C)(C)OC(=O)NCC(c1ccccc1)C(O)c1ccc(Br)cc1,,ClCCl,,CCN(CC)CC,,test
US05959146,CCN(CC)CC.O=C1OC(=O)c2ccccc21>>O=C1NC(=O)c2ccccc21,,Cc1ccccc1,,,,test
US03965151,O=C1CN2CCOC2(c2ccccc2Cl)c2cc([N+](=O)[O-])ccc2N1.OCCBr>>O=C1CN2CCOC2(c2ccccc2Cl)c2cc([N+](=O)[O-])ccc2N1CCO,,CN(C)C=O,,[H-].[Na+],,test
US04710585,CCC(C)CCCCCBr.Oc1ccc(O)cc1>>CCC(C)CCCCCOc1ccc(O)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100311966A1,CON.CO[C@@H]1CN(c2ncc(C(=O)O)s2)CC[C@@H]1NC(=O)c1nc(Cl)c(C)[nH]1>>CONC(=O)c1cnc(N2CC[C@H](NC(=O)c3nc(Cl)c(C)[nH]3)[C@H](OC)C2)s1,CN(C)c1ccncc1,,,CCN=C=NCCCN(C)C,Cl,test
US20070049603A1,C1CO1.COc1cccc2cc(Nc3coc4cnccc34)ccc12>>COc1cccc2cc(N(CCO)c3coc4cnccc34)ccc12,,C1CCOC1,,[Li]CCCC,,test
US20140073620A1,CC(NC(=O)OC(C)(C)C)c1ccc(Nc2ncc(C(F)(F)F)c(C#Cc3ccccc3C3(C(N)=O)CC3)n2)cc1>>CC(NC(=O)OC(C)(C)C)c1ccc(Nc2ncc(C(F)(F)F)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cc1,[Pd],CCOC(C)=O,CN(C)C=O,,,test
US05521177,CCCc1nc2c(Cl)cc(N3C(=O)c4ccccc4C3=O)cc2n1Cc1ccc(-c2ccccc2C(=O)OC)cc1>>CCCc1nc2c(Cl)cc(N)cc2n1Cc1ccc(-c2ccccc2C(=O)OC)cc1,,CCO,,CN,,test
US04963564,BrCCCCCCBr.OCCCc1ncccc1OCc1ccccc1>>BrCCCCCCOCCCc1ncccc1OCc1ccccc1,,O,,[Na+].[OH-],,test
US20090093454A1,N#CCBr.O=C1CCCc2cccnc21>>N#CCC1CCc2cccnc2C1=O,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US04665210,CCOC(=O)CC(C(=O)OCC)C(=O)OCC>>O=C(O)CC(C(=O)O)C(=O)O,,O,,[Na+].[OH-],,test
US06177440B1,COC(=O)c1cccc2c1c1c(O)cccc1n2Cc1cccc(Oc2ccccc2)c1.[NH4+]>>NC(=O)c1cccc2c1c1c(O)cccc1n2Cc1cccc(Oc2ccccc2)c1,,C1CCOC1,CCOC(C)=O,Cl,,test
US20060276469A1,C1CCNCC1.Cc1nc2ccc(I)cc2c(Cl)c1S(C)(=O)=O>>Cc1nc2ccc(I)cc2c(N2CCCCC2)c1S(C)(=O)=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05998433,CN(C)Cc1cc2c(o1)CN(C(=O)c1ccc(C3(c4ccccc4)CC3)cc1)CC2.Cl>>CN(C)Cc1cc2c(o1)CN(C(=O)c1ccc(C3(c4ccccc4)CC3)cc1)CC2.Cl,,CCOC(C)=O,CO,,,test
US20070099903A1,Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(=O)CC2)cc2oc(=O)[nH]c12.O=S1CCNCC1>>Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCS(=O)CC3)CC2)cc2oc(=O)[nH]c12,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20120053173A1,CCOC(=O)CCNC(=O)c1ccc(NC(c2oc3ccc(OC)cc3c2Br)C2CCCCC2)cc1>>COc1ccc2oc(C(Nc3ccc(C(=O)NCCC(=O)O)cc3)C3CCCCC3)c(Br)c2c1,,CCO,,C1CCOC1,[Na+].[OH-],test
US20090197863A1,CN(C)CCN.COC(=O)c1cccc2nc(-c3cccc(CBr)c3)oc12>>COC(=O)c1cccc2nc(-c3cccc(CNCCN(C)C)c3)oc12,,CCO,,,,test
US04092311,CCOC(=O)NN.Cc1cc(Cl)nnc1-c1ccccc1>>CCOC(=O)NNc1cc(C)c(-c2ccccc2)nn1,,CCCCO,,,,test
US20120309717A1,COC(=O)c1ccc(Cl)c([N+](=O)[O-])c1>>COC(=O)c1ccc(Cl)c(N)c1,[Pd],CCOC(C)=O,,,,test
US20120270893A1,O=C(OCc1ccccc1)c1cnc2cc[nH]c2c1.O=C1CCC(=O)N1Br>>O=C(OCc1ccccc1)c1cnc2c(Br)c[nH]c2c1,,CCOC(C)=O,CN(C)C=O,,,test
US05326770,N#CCCl.O=C1NC(=O)C(=Cc2ccc(OCCc3ccccc3)cc2)S1>>N#CCN1C(=O)SC(=Cc2ccc(OCCc3ccccc3)cc2)C1=O,,CN(C)C=O,,[H-].[Na+],,test
US09428452B2,Cc1ccc(N(CC(C)C)S(=O)(=O)c2ccc(OCC3CCOCC3)cc2Br)c(C)c1.O=C=O>>Cc1ccc(N(CC(C)C)S(=O)(=O)c2ccc(OCC3CCOCC3)cc2C(=O)O)c(C)c1,,C1CCOC1,,[Li]CCCC,,test
US20080269196A1,CC(C)(C)NC(=O)CCc1ccc(C#N)cc1>>CC(C)(C)NC(=O)CCc1ccc(CN)cc1,[Pd],CCO,,CC(=O)O,O,test
US20120245210A1,Brc1ccc(Br)s1.Cc1ncc[nH]1>>Cc1nccn1-c1ccc(Br)s1,[Cu]I,CS(C)=O,,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US04639518,COc1c([N+](=O)[O-])ccc(C=O)c1OS(=O)(=O)c1ccccc1>>COc1c(N)ccc(C=O)c1OS(=O)(=O)c1ccccc1,[Fe],CC(=O)O,O,,,test
US20150336962A1,C=O.CO.C[C@H](N)Cn1cc(NC(=O)c2cnn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1>>C[C@@H](Cn1cc(NC(=O)c2cnn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1)N(C)C,,CO,,[BH3-]C#N.[Na+],,test
US20060205942A1,O=C1CCC(=O)N1Br.O=Cc1cc(F)ccc1O>>O=Cc1cc(F)cc(Br)c1O,,CCOC(C)=O,CN(C)C=O,,,test
US04258060,CC(C)(C)N.ClC(Cl)(Cl)C1CO1>>CC(C)(C)NCC(O)C(Cl)(Cl)Cl,,CO,,,,test
US20120277224A1,CCOC(=O)CC(=O)c1cccc(F)c1.Nc1n[nH]c(N)c1-c1ccccn1>>Nc1nn2c(=O)cc(-c3cccc(F)c3)[nH]c2c1-c1ccccn1,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20030092770A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CS(=O)(=O)NCCc1ccc(I)cc1>>CC(C)(C)OC(=O)N(CCc1ccc(I)cc1)S(C)(=O)=O,CN(C)c1ccncc1,ClCCl,,,,test
US20150336949A1,CN.COc1ccc(Br)cc1S(=O)(=O)Cl>>CNS(=O)(=O)c1cc(Br)ccc1OC,,ClCCl,,CCN(CC)CC,Cl,test
US20160052888A1,C=CCO.Cc1ccc(S(=O)(=O)OCCOC2CCc3cc([C@H]4CC[C@]5(COC(=O)N5)C4)ccc3C2)cc1>>C=CCOCCOC1CCc2cc([C@H]3CC[C@]4(COC(=O)N4)C3)ccc2C1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20080319188A1,CNC1CCN(C)CC1.O=C(Oc1ccccc1)N(C(=O)Oc1ccccc1)c1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4F)CC3)c(F)c2)ccn1>>CN1CCC(N(C)C(=O)Nc2cc(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5F)CC4)c(F)c3)ccn2)CC1,,CN(C)C=O,,,,test
US20090221555A1,CN1CCOc2cc([N+](=O)[O-])ccc2C1=O>>CN1CCOc2cc(N)ccc2C1=O,[Pd],CCO,,,,test
US20050239826A1,OC1(CNCCOc2ccc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)cc2)CC1.OCCCBr>>OCCCN(CCOc1ccc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)cc1)CC1(O)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100056524A1,Cc1cccn(CCCNC(=O)OC(C)(C)C)c1=O.Cl>>Cc1cccn(CCCN)c1=O.Cl,,C1COCCO1,,,,test
US04939290,Nc1ccc(F)cc1F.O=C(O)c1cc(F)c(F)cc1Cl>>O=C(O)c1cc(F)c(F)cc1Nc1ccc(F)cc1F,[Cu],CN(C)C=O,,CCN(CC)CC,,test
US20040058903A1,COc1ccc(-c2ccccc2C(=O)Nc2ccc(N(CCc3ccccn3)C(=O)OC(C)(C)C)cc2)cc1>>O=C(Nc1ccc(NCCc2ccccn2)cc1)c1ccccc1-c1ccc(O)cc1,,CC(=O)O,,Br,,test
US06586441B2,CS(=O)c1nc(N)nc(-c2ccco2)c1Br.NCCNc1ccccc1>>Nc1nc(NCCNc2ccccc2)c(Br)c(-c2ccco2)n1,,C1COCCO1,,,,test
US04904653,BrBr.c1ccc(C2CNCCc3ccsc32)cc1>>Br.Brc1cc2c(s1)C(c1ccccc1)CNCC2,,CC(=O)O,,,,test
US20160068519A1,CCCCCCCC(=O)Cl.CCN(C(C)C)C(C)C>>CCCCCCCC(N)=O,,ClCCl,,[Na+].[OH-],,test
US20020002163A1,CC(C)C1=NC(N)C(=O)Nc2ccccc21.Cc1cccc(N=C=O)c1>>Cc1cccc(NC(=O)NC2N=C(C(C)C)c3ccccc3NC2=O)c1,,ClCCl,,,,test
US20100111862A1,C[C@H](O)C(F)(F)F.O=C(O)c1ccccc1F>>C[C@H](Oc1ccccc1C(=O)O)C(F)(F)F,,C1COCCO1,,O,[H-].[Na+],test
US20160002221A1,CC(C)(C#N)c1ccc(Br)cc1.OO>>CC(C)(C(N)=O)c1ccc(Br)cc1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20110160151A1,CC(=O)OC[C@@H](O)[C@@H](OCc1ccccc1)[C@H](OC(C)=O)[C@@H](O)C=O>>CC(=O)OC[C@@H](O)[C@@H](O)[C@H](OC(C)=O)[C@@H](O)C=O,[Pd],CCO,,[H][H],,test
US20150344423A1,CCOC(=O)c1cn(-c2cc(C(C)(C)C)cc(C3(C)CC3)c2)c(C(OC)C2CCCCC2)c1C>>COC(c1c(C)c(C(=O)O)cn1-c1cc(C(C)(C)C)cc(C2(C)CC2)c1)C1CCCCC1,,CS(C)=O,O,Cl,CC(C)(C)[O-].[K+],test
US20040147748A1,C=Cc1cnc(N)cn1.Cc1cc([C@@H](CC2CCCC2)C(=O)O)ccc1S(C)(=O)=O>>C=Cc1cnc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(C)(=O)=O)c(C)c2)cn1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20040266841A1,CCOCC.ClCc1ccc(Cl)cc1.N#Cc1ccc(Cl)cc1Cl>>O=C(Cc1ccc(Cl)cc1)c1ccc(Cl)cc1Cl,,Cc1ccccc1,ClCCl,II,[Mg],test
US20050107392A1,COC(=O)C(C)Br.COc1ccc2c(c1)CCC2=O>>COC(=O)C(C)C1=CCc2cc(OC)ccc21,[Zn],C1CCOC1,,,,test
US20130237571A1,CI.Oc1cc(F)c(Br)cc1F>>COc1cc(F)c(Br)cc1F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04661607,CCOC(=O)CBr.O=c1c2ccc(O)c(Cl)c2oc2cccc(Cl)c12>>O=C(O)COc1ccc2c(=O)c3c(Cl)cccc3oc2c1Cl,,CN(C)C=O,O,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US06900227B2,ClC(Cl)(c1ccccc1)c1ccccc1.O=C(O)c1cc(Cl)c(O)c(O)c1Cl>>O=C(O)c1cc(Cl)c2c(c1Cl)OC(c1ccccc1)(c1ccccc1)O2,,Cc1ccccc1,,,,test
US05674468,O=C(CCCCCCCCCCCCCCCOC(c1ccccc1)(c1ccccc1)c1ccccc1)OCOC(=O)CCCCCCCCCCCCCCCOC(c1ccccc1)(c1ccccc1)c1ccccc1>>O=C(CCCCCCCCCCCCCCCO)OCOC(=O)CCCCCCCCCCCCCCCO,,CC(=O)O,,,,test
US05925655,COC(=O)[C@H](CNC(=O)c1ccc2c(c1)C(=O)N(CCNc1ccccn1)C2)NS(=O)(=O)c1cccnc1>>O=C(NC[C@H](NS(=O)(=O)c1cccnc1)C(=O)O)c1ccc2c(c1)CNC2,,CO,,[Na+].[OH-],,test
US20050261291A1,Brc1ccccc1N1CCN(CC2CC2)CC1.CC1(C)CC(=O)CC(C)(C)C1>>CC1(C)CC(C)(C)CC(O)(c2ccccc2N2CCN(CC3CC3)CC2)C1,,C1CCOC1,CCOC(C)=O,O,[Li]CCCC,test
US20010044445A1,NNc1ccc([N+](=O)[O-])cc1.O=Cc1cccnc1>>O=[N+]([O-])c1ccc(NN=Cc2cccnc2)cc1,CC(=O)O,CCO,,,,test
US20030153564A1,CC(C)(C)OC(=O)N1CC2CN(Cc3ccccc3)CC(C1)O2.Cl>>CC(C)(C)OC(=O)N1CC2CN(Cc3ccccc3)CC(C1)O2.Cl,,CCOC(C)=O,CCOCC,N#N,,test
US20080175814A1,Cc1cc(Cl)nc(N)n1.Cl.Nc1ccc(C(=O)O)cc1>>Cc1cc(Nc2ccc(C(=O)O)cc2)nc(N)n1.Cl,,CCOCCO,,,,test
US05219847,CCCCOc1cccc(C)n1.O=C(OO)c1cccc(Cl)c1>>CCCCOc1cccc(C)[n+]1[O-],,CCOCC,,,,test
US20080269196A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N#Cc1ccc(OC2CCCCCC2)cn1>>CC(C)(C)OC(=O)NCc1ccc(OC2CCCCCC2)cn1,[Pd],CCO,,[H][H],,test
US05539112,CN1CCN(c2c(F)c(NC(=O)C(C)(C)C)c3c(=O)cc(-c4ccc(NC(=O)C(C)(C)C)c(F)c4)oc3c2F)CC1>>CN1CCN(c2c(F)c(N)c3c(=O)cc(-c4ccc(N)c(F)c4)oc3c2F)CC1,,C1COCCO1,,Cl,,test
US20140113882A1,CC(C)(C)OC(=O)N1CCNCC1.CCCCc1cncc2nc(-c3ccncc3)nc(Cl)c12>>CCCCc1cncc2nc(-c3ccncc3)nc(N3CCN(C(=O)OC(C)(C)C)CC3)c12,,ClCCl,,CCN(CC)CC,O=C([O-])[O-].[Na+].[Na+],test
US20030158185A1,CCOCC.Fc1cc(Br)c(F)cc1Br.O>>O=Cc1cc(F)c(Br)cc1F,,O,,[Li]CCCC,,test
US20130029970A1,COc1ccc(C(=O)c2cc3cc(C)n(CCN4CCOCC4)c3s2)cn1.Cc1ccc(S(=O)(=O)O)cc1>>COc1ccc(C(=O)c2cc3cc(C)n(CC[NH+]4CCOCC4)c3s2)cn1.Cc1ccc(S(=O)(=O)[O-])cc1,,CCOCC,,,,test
US20040186301A1,C=C(CC(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OCC.SC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)C(CSC(c1ccccc1)(c1ccccc1)c1ccccc1)CC(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,C1CCOC1,,CCCCCC,[H-].[Na+],test
US20110105544A1,O=C(O)C(CCc1ccccc1)(CCc1ccccc1)C(=O)O>>O=C(O)C(CCc1ccccc1)CCc1ccccc1,,CS(C)=O,,O,,test
US06627651B1,CCCOc1ccc(OB(O)O)cc1.COC(=O)C1=Cc2cc(O)ccc2S(=O)(=O)CC1>>CCCOc1ccc(Oc2ccc3c(c2)C=C(C(=O)OC)CCS3(=O)=O)cc1,,CCN(CC)CC,,ClCCl,,test
US20030158256A1,C=CCOC(=O)c1cccc(COC[C@H](C#N)NC(=O)OC(C)(C)C)c1>>CC(C)(C)OC(=O)N[C@@H](C#N)COCc1cccc(C(=O)O)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,C1COCCN1,,test
US20060270656A1,C=O.c1ccc(CC[C@H]2CN(C3=Nc4ccccc4Sc4ccccc43)CCN2)cc1>>CN1CCN(C2=Nc3ccccc3Sc3ccccc32)C[C@@H]1CCc1ccccc1,,CC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04455422,COc1ccccc1N1CCN(CCC(O)c2ccc3c(c2)CCC(=O)N3)CC1>>COc1ccccc1N1CCN(CC=Cc2ccc3c(c2)CCC(=O)N3)CC1,,C1COCCO1,,Cl,[Na+].[OH-],test
US04468394,CCn1cc(C(=O)O)c(=O)c2cc(OC(C)=O)c(OC(C)=O)cc21.O=S(Cl)Cl>>CCn1cc(C(=O)Cl)c(=O)c2cc(OC(C)=O)c(OC(C)=O)cc21,CN(C)C=O,c1ccccc1,,,,test
US20070032487A1,CCOC(=O)CN=C=O.Cc1nc(N)sc1-c1ccncc1>>CCOC(=O)CNC(=O)Nc1nc(C)c(-c2ccncc2)s1,,CN(C)C=O,,CCOC(C)=O,,test
US05939447,COC(=O)c1ccc(O)cc1.ClCCCC1(c2ccccc2)OCCO1>>COC1(c2ccc(OCCCC(=O)c3ccccc3)cc2)OCCO1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05256675,O=CNc1nc(CCl)cs1.O=[N+]([O-])c1ccc(S)cc1>>O=CNc1nc(CSc2ccc([N+](=O)[O-])cc2)cs1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150252030A1,COC(=O)COc1ccc(OC)cc1-c1ccco1.NN>>COc1ccc(OCC(=O)NN)c(-c2ccco2)c1,,CCO,,,,test
US20130109679A1,CC(C)(C)OC(=O)N1CCC(C#N)(COCc2ccccc2)CC1>>CC(C)(C)OC(=O)N1CCC(CN)(COCc2ccccc2)CC1,[Ni],CO,,N,,test
US20160159767A1,COC1=C(Br)COC1=O.O=C1CCC(=O)N1Br>>COC1=C(Br)C(Br)OC1=O,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20090054407A1,CC(C)(C)OC(=O)n1c(-c2ccc(Cl)c3c2C(=O)NC3)cc2cc(C=O)ccc21.NCCc1ccncc1>>CC(C)(C)OC(=O)n1c(-c2ccc(Cl)c3c2C(=O)NC3)cc2cc(CNCCc3ccncc3)ccc21,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20040116704A1,O=C(O)[C@H](O)[C@@H](O)C(=O)O.O=C1C2CCN(CC2)C1C(c1ccccc1)c1ccccc1>>O=C(O)[C@H](O)[C@@H](O)C(=O)O.O=C1C2CCN(CC2)[C@H]1C(c1ccccc1)c1ccccc1,,CCO,,CC(=O)O,,test
US04776929,CCCCN(CCCC)CCCC.COC(=O)OC>>CCCC[NH+](CCCC)CCCC.O=C([O-])O,,CO,,O,,test
US20020103229A1,CCON=Cc1ccc2[nH]nc(-c3cccc(C(=O)Nc4ccc(F)cc4)c3)c2c1.CN(C)CC(=O)NN.Cl.Cl>>CN(C)Cc1n[nH]c(-c2ccc3[nH]nc(-c4cccc(C(=O)Nc5ccc(F)cc5)c4)c3c2)n1.Cl.Cl,,CCOC(C)=O,CO,Cl,C[O-].[Na+],test
US20040116697A1,CSc1nc(Cl)c(C=O)c(Cl)n1.NC1CCCCC1>>CSc1nc(Cl)c(C=O)c(NC2CCCCC2)n1,,CC#N,O,,,test
US06057311,CC1CCN(C(=O)OC(C)(C)C)CC(=O)N(Cc2ccccc2)c2ccccc21>>CC1CCNCC(=O)N(Cc2ccccc2)c2ccccc21,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20060122391A1,CC(C)(C)C(=O)C(O)CC(O)CCO.CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1>>CC(C)(C)C(=O)C(O)CC(O)CC(O)[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,ClCCl,,c1c[nH]cn1,,test
US20130065881A1,CN1CCOc2c1c(Cl)nn1cnnc21.O=C1CCC(=O)N1Br>>CN1CCOc2c1c(Cl)nn1c(Br)nnc21,,ClC(Cl)Cl,ClCCl,,,test
US20150094474A1,CC1(C)C(/C=C(\Cl)C(F)(F)F)C1C(=O)Cl.OCc1cccc(Oc2ccccc2)c1>>CC1(C)C(/C=C(\Cl)C(F)(F)F)C1C(=O)OCc1cccc(Oc2ccccc2)c1,,CCOC(C)=O,Cc1ccccc1,c1ccncc1,,test
US20010018448A1,C=O.CCCCc1nccn1Cc1ccccc1Cl>>CCCCc1ncc(CO)n1Cc1ccccc1Cl,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20120245144A1,CC(c1ccc2c(c1)-c1nc(-c3ncnn3C(C)C)cn1CCO2)N1CC(OS(C)(=O)=O)C1.CNC>>CC(c1ccc2c(c1)-c1nc(-c3ncnn3C(C)C)cn1CCO2)N1CC(N(C)C)C1,,C1COCCO1,,,,test
US05179125,CC(=O)SCC(Cc1ccccc1)C(=O)Cl.CCc1cc(N)cc(C(=O)O)c1>>CCc1cc(NC(=O)C(CSC(C)=O)Cc2ccccc2)cc(C(=O)O)c1,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US05061289,Cn1ncc(N)c1[N+](=O)[O-].O=S(=O)(O)O>>C[n+]1[nH]cc(N)c1N.O.O=S(=O)([O-])O,[Pd],CO,,,,test
US05646265,CCCBr.Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1>>CCCO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1ccc(N)nc1=O,,CN(C)C=O,,[H-].[Na+],,test
US20120277228A1,COc1ccc(C=O)cc1.NCCNC(=O)c1sccc1Nc1ccnc2[nH]ccc12>>COc1ccc(CNCCNC(=O)c2sccc2Nc2ccnc3[nH]ccc23)cc1,,CO,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20030069257A1,CCCc1cc(N)c(NCC)cn1.COC(=O)Cn1ccnc1-c1cccc(F)n1>>CCCc1cc2nc(Cn3ccnc3-c3cccc(F)n3)n(CC)c2cn1,,ClCCCl,,C[Al](C)C,,test
US05536718,CN(C)CCNc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cn1.Cc1ccc(F)cc1C(=O)Cl>>Cc1ccc(F)cc1C(=O)N(CCN(C)C)c1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cn1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080221110A1,CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)C1CCN(CC2(O)Cn3c(=O)ccc4ccc(Br)c2c43)CC1.N#C[Cu]>>CC(C)(C)OC(=O)N(Cc1cc2c(cn1)OCCO2)C1CCN(CC2(O)Cn3c(=O)ccc4ccc(C#N)c2c43)CC1,,CN(C)C=O,,,,test
US20050222160A1,CCOc1cc(C2=NNCCC2)ccc1OC.Cc1nc(-c2cccnc2)sc1C(=O)Cl>>CCOc1cc(C2=NN(C(=O)c3sc(-c4cccnc4)nc3C)CCC2)ccc1OC,,ClCCl,,Cl,c1ccncc1,test
US20120208798A1,CC(=O)N1c2ccc(C#C[Si](C)(C)C)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C>>C#Cc1ccc2c(c1)[C@H](NC(=O)OC(C)C)C[C@H](C)N2C(C)=O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05068334,COC(=O)CBr.O=C1CCC2=C(CCCC2=O)N1>>COC(=O)CN1C(=O)CCC2=C1CCCC2=O,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20090105253A1,CCCc1c(C(=O)NC2CC2)nnn1-c1ccc(NC(=O)CC(=O)OCC)cc1>>CCCc1c(C(=O)NC2CC2)nnn1-c1ccc(NC(=O)CC(=O)O)cc1,,CO,,O,O=C([O-])[O-].[Na+].[Na+],test
US04101665,ClCC1CO1.O=[N+]([O-])c1ccccc1O>>O=[N+]([O-])c1ccccc1OCC1CO1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160083379A1,CC(C)(C)OC(=O)Nc1cncc(Br)c1.CI>>CN(C(=O)OC(C)(C)C)c1cncc(Br)c1,,C1CCOC1,,[H-].[Na+],,test
US20140336190A1,Cc1noc(C)c1-c1cc(C(O)C2OCCO2)c2nc(C3CC3)n(C(=O)OC(C)(C)C)c2c1>>Cc1noc(C)c1-c1cc(C(=O)C2OCCO2)c2nc(C3CC3)n(C(=O)OC(C)(C)C)c2c1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20150191461A1,C[C@@H](NC(=O)OC(C)(C)C)C(=O)C=[N+]=[N-].Cl>>C[C@@H](NC(=O)OC(C)(C)C)C(=O)CCl,,CCOCC,,,,test
US20100273806A1,CCN(CC)c1cc(C(F)(F)F)cc(Cl)n1.N#C[Zn]C#N>>CCN(CC)c1cc(C(F)(F)F)cc(C#N)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US03932644,CCOc1cc(NCCSCc2[nH]cnc2C)nc2ccccc12>>Cc1nc[nH]c1CSCCNC1=Nc2ccccc2C(=O)C1,,Cl,,,,test
US20150011512A1,Cc1cc(=O)oc2cc(O)ccc12.ClCc1cc2cc(Br)ccc2o1>>Cc1cc(=O)oc2cc(OCc3cc4cc(Br)ccc4o3)ccc12,,CN(C)C=O,,C,C[O-].[Na+],test
US04018802,CC(=O)OC(C#CCOC1CCCCO1)COc1cccc(C(F)(F)F)c1>>CC(=O)OC(CCCOC1CCCCO1)COc1cccc(C(F)(F)F)c1,[Pd],CCOC(C)=O,,[H][H],,test
US20080221096A1,CCOC(=O)COc1nc(N(C)Cc2ccccc2)c2c(c1C#N)CC(C)(C)OC2>>CCOC(=O)c1oc2nc(N(C)Cc3ccccc3)c3c(c2c1N)CC(C)(C)OC3,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05308853,CCCCI.CCOP(=O)(OCC)C1=NC(=O)NC1=O>>CCCCN1C(=O)N=C(P(=O)(OCC)OCC)C1=O,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20160016948A1,CC(C)n1cnc2cnc(Nc3ccnc(Cl)n3)cc21.c1cn2c(n1)CNCC2>>CC(C)n1cnc2cnc(Nc3ccnc(N4CCn5ccnc5C4)n3)cc21,,CC(C)O,,CCN(CC)CC,,test
US20070010526A1,Cl.O=C(Cl)C(=O)Cl.O=C(O)c1cccc2ncccc12>>Cl.O=C(Cl)c1cccc2ncccc12,,ClCCl,,,,test
US20080004271A1,CC(C)CN.CS(=O)c1nc(-c2ccc(Cl)c(Cl)c2)c2c(N)c(C(N)=O)sc2n1>>CC(C)CNc1nc(-c2ccc(Cl)c(Cl)c2)c2c(N)c(C(N)=O)sc2n1,,CC#N,O,C1CCOC1,,test
US05126497,N#Cc1ccc(C(F)(F)F)cc1>>Cc1ccc(C(F)(F)F)cc1,,CO,,,,test
US20120149681A1,CC(C)(C)OC(=O)N1CCC(Oc2cc(F)cc(Br)c2)CC1.CN(C)C=O>>CC(C)(C)OC(=O)N1CCC(Oc2cc(F)cc(C=O)c2)CC1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20060167055A1,O=[N+]([O-])c1ccc(Br)cn1.Oc1ccccc1F>>O=[N+]([O-])c1ccc(Oc2ccccc2F)cn1,,O,,CN(C)C=O,[H-].[Na+],test
US05346911,CCOC(=O)C1=CC[C@@H]2CC[C@H]1N2C.[Li]C>>CC(=O)C1=CCC2CCC1N2C,,C1CCOC1,,C[Si](C)(C)Cl,,test
US04841042,C=CCOC(=O)C1=C(Sc2ccncc2)C[C@@H]2[C@H]([C@@H](CO[SiH](C)C)C(C)(C)C)C(=O)N12>>C=CCOC(=O)C1=C(Sc2ccncc2)C[C@@H]2[C@@H]([C@@H](C)O)C(=O)N12,,C1CCOC1,,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20020052400A1,C=CC#N.COc1ccc2ccc(O)c(C=O)c2c1>>COc1ccc2ccc3c(c2c1)C=C(C#N)CO3,,CCOC(C)=O,,C1CN2CCN1CC2,,test
US20090318690A1,CC(C)(C)OC(=O)N1CCC(CCc2noc3c(CO)c(-c4ccc(C#N)cc4)ccc23)CC1.CCN(CC)CC>>CN(C)Cc1c(-c2ccc(C#N)cc2)ccc2c(CCC3CCN(C(=O)OC(C)(C)C)CC3)noc12,,C1CCOC1,,CS(=O)(=O)Cl,,test
US06545033B1,CC(=O)C1CCCC1=O.NNc1c(Cl)cc(C(F)(F)F)cc1Cl>>Cc1c2c(nn1-c1c(Cl)cc(C(F)(F)F)cc1Cl)CCC2,,CCO,,,,test
US20060025445A1,NCC(=O)c1ccccc1.O=S(=O)(Cl)c1ccccc1>>O=C(CNS(=O)(=O)c1ccccc1)c1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
US20070179148A1,CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCN(c2ccc(Cl)c(Cl)c2)CC1)C(C)(C)C>>CC(C)(C)[C@@H](N)C(=O)N1CCN(c2ccc(Cl)c(Cl)c2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100298336A1,Cn1cnc(C=O)c1Cl>>Cn1cnc(CO)c1Cl,,CO,,O,[BH4-].[Na+],test
US20080214598A1,CC(=O)NCCc1ccc(Cl)c(C(C)(C)O[SiH2]C(C)(C)C)c1>>CC(=O)NCCc1ccc(Cl)c(CO)c1,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20100022598A1,CN(C)S(=O)(=O)n1cc(CC2(C(F)(F)F)CC2)nc1[C@H](O)[C@](O)(c1ccc(-n2cccn2)cc1)C(F)(F)F>>O[C@H](c1nc(CC2(C(F)(F)F)CC2)c[nH]1)[C@@](O)(c1ccc(-n2cccn2)cc1)C(F)(F)F,,CO,,Cl,,test
US20140206673A1,CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)C(C(=O)O)C1.CCBr>>CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCN1C(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20010003747A1,CC(=O)OC(C)=O.COc1ccc2c(c1)N(CC#N)C(c1ccccc1)CO2>>COc1ccc2c(c1)N(CCNC(C)=O)C(c1ccccc1)CO2,[Ni],CC(=O)OC(C)=O,,CC(=O)[O-].[Na+],,test
US05587386,CC(C)(C)OC(=O)NC(C#N)c1ccccc1.C[C@H](c1ccccc1)N1CC(N)C(C)(C)C1>>C[C@H](c1ccccc1)N1CC(NC(=O)OC(C)(C)C)C(C)(C)C1,,C1CCOC1,,,,test
US04642307,BrCC1CO1.Oc1cccc(N2CCCCC2)c1Cl>>Clc1c(OCC2CO2)cccc1N1CCCCC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05750720,COS(=O)(=O)OC.Cc1c(Br)sc(Br)c1Br>>Cc1sc(Br)c(C)c1Br,,CCOCC,,[Li]CCCC,,test
US20060122399A1,CCc1cc(Br)ccc1C(=O)O.CN(C)C=O>>CCc1cc(Br)ccc1-c1ncco1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110166169A1,COCCCN.N#Cc1ccc(-n2c3ccccc3c3c(-c4nc5ccc(F)cc5[nH]4)cccc32)cc1F.OO>>COCCCNc1cc(-n2c3ccccc3c3c(-c4nc5ccc(F)cc5[nH]4)cccc32)ccc1C(N)=O,,CCO,CS(C)=O,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US04973599,Cn1ccnc1S.O=[N+]([O-])c1ccc(Cl)cc1[N+](=O)[O-]>>Cn1ccnc1Sc1cc(Cl)ccc1[N+](=O)[O-],,CCO,,C[O-].[Na+],,test
US20090099190A1,CON(C)c1cc(NC(C)C)c(CNc2cc([N+](=O)[O-])c(F)cc2C)cn1.O=C(Cl)OC(Cl)(Cl)Cl>>CON(C)c1cc2c(cn1)CN(c1cc([N+](=O)[O-])c(F)cc1C)C(=O)N2C(C)C,,C1COCCO1,,CCN(CC)CC,,test
US20120115882A1,CC(C)(C)OC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]1CO.O=C(O)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N1C[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]1COC(=O)c1ccc([N+](=O)[O-])cc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04677129,CC(C)N1C(=O)C2CC(c3ccc([N+](=O)[O-])cc3)(C2)C1=O>>CC(C)N1C(=O)C2CC(c3ccc(N)cc3)(C2)C1=O,[Pd],CCOC(C)=O,,CCCCCC,,test
US20110028501A1,Nc1ccc(O)cc1.O=CNNC=O>>Oc1ccc(-n2cnnc2)cc1,,CN(C)C=O,Cc1ccccc1,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100105659A1,N#Cc1ncc(Br)cc1[N+](=O)[O-].Oc1ccc(F)cc1Br>>N#Cc1ncc(Br)cc1Oc1ccc(F)cc1Br,,CN(C)C=O,O,[H-].[Na+],[Cl-].[NH4+],test
US04771065,O=C(Cn1cncn1)c1ccc(Cl)cc1Cl>>OC(Cn1cncn1)c1ccc(Cl)cc1Cl,,CO,,[BH4-].[Na+],,test
US20130085127A1,OC(c1ccccc1)c1ccc(F)cc1F.OC1CCNCC1>>Fc1ccc(C(OC2CCNCC2)c2ccccc2)c(F)c1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20150209352A1,C=CCC(CO)(C[C@H](N)Cc1ccc(-c2cc(Cl)ccc2F)cc1)C(=O)O.O=C(O)c1c[nH]nn1>>C=CCC(CO)(C[C@@H](Cc1ccc(-c2cc(Cl)ccc2F)cc1)NC(=O)c1cnn[nH]1)C(=O)O,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040009991A1,CC(=O)C(=Cc1cc(Cl)cc(Cl)c1)C(=O)NCCCc1ccccc1.CC(C)(C)C(=N)N>>Cc1nc(C(C)(C)C)nc(-c2cc(Cl)cc(Cl)c2)c1C(=O)NCCCc1ccccc1,,CN(C)C=O,,Cl,CC(=O)[O-].[Na+],test
US05399575,Cc1ccccn1.N#Cc1ccc(C=O)cc1>>N#Cc1ccc(C=Cc2ccccn2)cc1,,CCOCC,,CC(=O)OC(C)=O,,test
US20090264403A1,CN(C)[C@@H]1CCN(c2ccc(N3CCc4cc(O)ccc4C3=O)cc2F)C1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CN(C)[C@@H]1CCN(c2ccc(N3CCc4cc(OS(=O)(=O)C(F)(F)F)ccc4C3=O)cc2F)C1,,ClCCl,,c1ccncc1,,test
US04663336,C=CC(=O)OC.Sc1ccccc1>>COC(=O)CCSc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20150218170A1,Cc1cc(Nc2nc3c(C(=O)NC(C)(C)C)cn(COCC[Si](C)(C)C)c3nc2Cl)sn1>>Cc1cc(Nc2nc3c(C(=O)NC(C)(C)C)c[nH]c3nc2Cl)sn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070172421A1,CN(C)C=O.Cn1cncc1-c1ccc2c(c1)OCO2>>Cn1c(-c2ccc3c(c2)OCO3)cnc1C=O,,C1CCOC1,,CCOCC,[Li]CCCC,test
US20040039206A1,BrCc1ccccc1.CN(C)C(=O)[C@H]1CCCNC1>>CN(C)C(=O)[C@H]1CCCN(Cc2ccccc2)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070117824A1,CC(C)(C)OC(=O)N1CCC2(CC1)CC(C(=O)O)=NO2.CCOC(C)=O.CN(C)C=O.ClCCCl.NCCc1ccccc1.On1nnc2ccccc21>>Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc(N2CCC3(CC2)CC(C(=O)NCCc2ccccc2)=NO3)nc1,,CCOC(C)=O,,,,test
US20130237535A1,CC1CC2(CCN1C(=O)OC(C)(C)C)CN(C1CC1)C(=O)CO2.O=S(=O)(Cl)c1ccc(Br)cc1>>CC1CC2(CCN1S(=O)(=O)c1ccc(Br)cc1)CN(C1CC1)C(=O)CO2,CN(C)c1ccncc1,C1COCCO1,CCOC(C)=O,Cl,,test
US20110207213A1,CC#N.CCN(C(C)C)C(C)C.Nc1ccccc1N=Nc1ccccc1>>CCCc1ccc(N=Nc2ccc(N)cc2)cc1,,CN(C)C=O,,,,test
US20100105664A1,CC(C)(C)OC(=O)N1CCN(c2[nH]c(-c3ccnc(Cl)c3)cc2C#N)CC1.OB(O)/C=C/c1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCN(c2[nH]c(-c3ccnc(/C=C/c4ccc(F)cc4)c3)cc2C#N)CC1,,CCCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20090093483A1,CC(C#N)c1ccccc1C#C[Si](C)(C)C>>C#Cc1ccccc1C(C)C#N,,C1CCOC1,,Cl,[Na+].[OH-],test
US20090069288A1,CC(C)(C)OC(=O)NC1(c2ccc([N+](=O)[O-])cc2)CC1>>CC(C)(C)OC(=O)NC1(c2ccc(N)cc2)CC1,O=[Pt]=O,C1CCOC1,,O=S(=O)([O-])[O-].[Mg+2],,test
US20090076086A1,Cc1ccc(S(=O)(=O)CCO)cc1.O=C(O)c1cccnc1S>>Cc1ccc(S(=O)(=O)CCSc2ncccc2C(=O)O)cc1,,CN(C)C=O,,O=S(=O)(O)O,,test
US20110281865A1,COC(=O)c1ccc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)cc1F>>O=C(O)c1ccc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)cc1F,,CO,O,Cl,[Li+].[OH-],test
US20030149035A1,C#CCCCO.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCOCC3)cc(I)c21>>Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCOCC3)cc(C#CCCCO)c21,[Cu]I,CCNCC,,CN(C)C=O,,test
US07361665B2,COC(OC)C(Cl)C(C)=O.N=C(N)c1ccccc1>>CC(=O)c1cnc(-c2ccccc2)[nH]1,,C1COCCO1,,CC(=O)[O-].[Na+],,test
US04064236,CC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O.CCOC(=O)[C@](C)(O)C(=O)N(C)N>>CCOC(=O)[C@](C)(O)C(=O)N(C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(C)=O,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20030158245A1,CC(C)(C)OC(=O)CSC(NCc1ccccc1)=C1C(=O)CCCC1=O>>CC(C)(C)OC(=O)c1sc(NCc2ccccc2)c2c1CCCC2=O,,CC(C)O,,CC(C)(C)[O-].[K+],,test
US20020107251A1,Cc1nc2cccnc2n(-c2cccc(NC(=O)c3cc(Cl)cc(Cl)c3)c2)c1=O.O=C1CCC(=O)N1Br>>O=C(Nc1cccc(-n2c(=O)c(CBr)nc3cccnc32)c1)c1cc(Cl)cc(Cl)c1,,ClC(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20050014759A1,COc1ccc(C(=O)c2cc(C#N)c3cnc4ccccc4n23)cc1>>COc1ccc(C(=O)c2cc(C#N)c3n2-c2ccccc2NC3)cc1,,CC(C)=O,CO,,,test
US20140051676A1,CN.CN(c1ccccc1)c1nc(N)nc(-c2noc(-c3ccc(C(=O)O)s3)n2)n1>>CNC(=O)c1ccc(-c2nc(-c3nc(N)nc(N(C)c4ccccc4)n3)no2)s1,,CN(C)C=O,ClCCl,O=C(n1ccnc1)n1ccnc1,,test
US20100137299A1,BrCC1CCCCO1.O=C1Nc2ccccc2C12COc1cc3c(cc12)CCO3>>O=C1N(CC2CCCCO2)c2ccccc2C12COc1cc3c(cc12)CCO3,,CCC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080318947A1,CCn1c(-c2nonc2N)nc2c(Cl)nc(Br)cc21.O=Cc1ccccc1>>CCn1c(-c2nonc2N)nc2c(Cl)nc(C(O)c3ccccc3)cc21,,C1CCOC1,,[Li]CCCC,,test
US20060276496A1,NO.O=C(Nc1cccnc1)c1ccc2[nH]c3c(c2c1)CCCC3=O>>O=C(Nc1cccnc1)c1ccc2[nH]c3c(c2c1)CCCC3=NO,,CO,,Cl,CC(=O)[O-].[Na+],test
US06495700B1,CN1CC[C@@]2(C)c3cc(O)ccc3N(C)[C@@H]12.O=C=Nc1ccccc1>>CN1CC[C@@]2(C)c3cc(OC(=O)Nc4ccccc4)ccc3N(C)[C@@H]12,,COCCOC,,O,[Li]CCCC,test
US05268512,O=C(O)c1ccccc1.Oc1ccccc1>>c1ccc(Oc2ccccc2)cc1,[Cu],,,,,test
US20160068512A1,NCCO.O=C(O)c1ccc(S(=O)(=O)Cl)cc1>>O=C(O)c1ccc(S(=O)(=O)NCCO)cc1,,ClCCl,ClCCl,CCN(CC)CC,,test
US20070281943A1,CC(C)I.O=[N+]([O-])c1ccc(C2CCNCC2)cc1>>CC(C)N1CCC(c2ccc([N+](=O)[O-])cc2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04699651,CCOC(=O)C(=NNc1ccccc1CC)C(=O)OCC>>CCc1ccccc1NN=C(C(=O)O)C(=O)O,,CCO,,[Na+].[OH-],,test
US20030225053A1,COC(=O)c1cc2cccc(N)c2s1.O=C(O)c1cccnc1>>COC(=O)c1cc2cccc(NC(=O)c3cccnc3)c2s1,,ClCCl,,CCN(CC)CC,,test
US20070117793A1,CCOC(=O)c1cc(CSC(C)=O)cc(C(=O)OCC)c1.CI>>CCOC(=O)c1cc(CSC)cc(C(=O)OCC)c1,,C1CCOC1,CO,C[O-].[Na+],,test
US20090312310A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)c(N)c3)[C@H]2c2ccc(Cl)cc2)S1>>COC(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)c(NC(=O)OC(C)(C)C)c3)[C@H]2c2ccc(Cl)cc2)S1,CN(C)c1ccncc1,CC#N,,,,test
US20040053908A1,NCCF.O=C(Cl)Oc1ccccc1>>O=C(NCCF)Oc1ccccc1,,CCOC(C)=O,CN(C)C=O,O,c1ccncc1,test
US20100105658A1,CCOC(=O)c1nc(C#N)sc1-c1ccccc1.[OH-]>>NC(=O)c1nc(C(=O)O)c(-c2ccccc2)s1,,C1CCOC1,,Cl,,test
US20090093464A1,N#Cc1ccc(N2CCCCN2)c2ccccc12.O=C(O)Cc1ccccc1OC(F)(F)F>>N#Cc1ccc(N2CCCCN2C(=O)Cc2ccccc2OC(F)(F)F)c2ccccc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130053397A1,COC(=O)c1ccc(-c2cc(C(=O)NCc3c(C)cc(C)[nH]c3=O)c3c(C)cn(C(C)C)c3c2)cc1>>Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(C(=O)O)cc3)cc3c2c(C)cn3C(C)C)c(=O)[nH]1,,C1CCOC1,CO,[Na+].[OH-],,test
US05034404,CN(C)C(=N)N[N+](=O)[O-].ClCc1ccc(Cl)nc1>>CN(C)C(=N[N+](=O)[O-])NCc1ccc(Cl)nc1,,CN(C)C=O,,[H-].[Na+],,test
US20130123235A1,CC(C)(C)O.Nc1ccc(Br)c(O)c1C(=O)O>>CC(C)(C)OC(=O)c1c(N)ccc(Br)c1O,CN(C)c1ccncc1,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20100331335A1,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].COc1ccc(CC(=O)Nc2sccc2C#N)cc1>>COc1ccc(CC(=O)Nc2sccc2-c2nn[nH]n2)cc1,,Cc1ccccc1,,,,test
US20090156604A1,O=Cc1ccc(-c2nc3ccccn3c2Br)cc1.OB(O)c1ccc(F)cc1>>O=Cc1ccc(-c2nc3ccccn3c2-c2ccc(F)cc2)cc1,,Cc1ccccc1,O,CCO,O=C([O-])[O-].[K+].[K+],test
US20090105253A1,CCNC(=O)c1ccc(-n2nnc(C(=O)O)c2CCC(C)C)cc1.NC1CC1>>CCNC(=O)c1ccc(-n2nnc(C(=O)NC3CC3)c2CCC(C)C)cc1,,CC#N,CN(C)C=O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20100076021A1,CNC.COC(=O)/C=C/c1ncc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1>>COC(=O)CC(c1ncc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1)N(C)C,,C1CCOC1,,,,test
US04864021,Cc1ccccc1CBr.O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1F>>Cc1ccccc1C[C@]1(O)C[C@H](n2cc(F)c(=O)[nH]c2=O)O[C@@H]1CO,,CC#N,O,[K+].[OH-],,test
US20110218200A1,CN1CCNCC1.O=[N+]([O-])c1ccc(Br)cc1NCc1ccccc1>>CN1CCN(c2ccc([N+](=O)[O-])c(NCc3ccccc3)c2)CC1,,CN1CCCC1=O,,O,,test
US20080114007A1,CC(C)(C)OC(=O)N1CCN(CCc2ccc(N)cc2)CC1.CONC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(S(C)(=O)=O)ncc2c1=O>>CONC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(Nc3ccc(CCN4CCNCC4)cc3)ncc2c1=O,,CC(=O)O,,,,test
US20060025597A1,Nc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C(Cl)c1ccccn1>>O=C1CCC(N2C(=O)c3cccc(NC(=O)c4ccccn4)c3C2=O)C(=O)N1,,C1CCOC1,CO,Cl,,test
US20110021520A1,CCOC(=O)c1nc(C)oc1NC(=O)OC(C)(C)C>>Cc1nc(C(=O)O)c(NC(=O)OC(C)(C)C)o1,,C1CCOC1,,Cl,[Na+].[OH-],test
US06060462,O=C(CN(CCc1ccccc1)C(=O)CCc1ccccc1)OCc1ccccc1>>O=C(O)CN(CCc1ccccc1)C(=O)CCc1ccccc1,[Pd],CO,,[H][H],,test
US20090306133A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](CNC(=O)c2cc(-c3ccncc3)nc3ccccc23)CC1.Cl>>Cl.NC[C@@H]1CC[C@@H](CNC(=O)c2cc(-c3ccncc3)nc3ccccc23)CC1,,ClCCl,,CCOC(C)=O,,test
US20090156600A1,CC(=O)OC(F)(F)Cl.COC(=O)COc1ccc(F)c2[nH]c(=O)c(Cc3ccc(Cl)cc3)c(C)c12>>COC(=O)COc1ccc(F)c2nc(OC(F)F)c(Cc3ccc(Cl)cc3)c(C)c12,,O,,O=C([O-])[O-].[K+].[K+],,test
US20070213338A1,CC(C)(C)[Si](C)(C)OCc1cccc(COc2cnc(Cl)c3ccccc23)n1.NNC(=O)C(F)(F)F>>OCc1cccc(COc2cn3c(C(F)(F)F)nnc3c3ccccc23)n1,,CCCCO,,Cl,,test
US20110053921A1,CC(=O)CCl.O=C1Nc2cnc(Cl)nc2N2CCOCC12>>CC(=O)CN1C(=O)C2COCCN2c2nc(Cl)ncc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160176864A1,CC(F)(F)CO.CS(=O)(=O)c1ccc(F)c2c1[nH]c1cc(Br)cnc12>>CS(=O)(=O)c1ccc(OCC(F)F)c2c1[nH]c1cc(Br)cnc12,,CCOC(C)=O,CN1CCCC1=O,CC(C)(C)[O-].[K+],,test
US20140193707A1,BrCBr.CN1CCCC1>>C[N+]1(CBr)CCCC1.[Br-],,C1CCOC1,,,,test
US20070066820A1,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc(C(=O)c2ccccc2)cn1>>CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc(C(O)c2ccccc2)cn1,,CCO,O,[BH4-].[Na+],,test
US20150105366A1,COc1nc2ccc(C(=O)c3cnc(C)n3C)cc2c(Cl)c1Cc1ccc(F)cc1.Cc1ncc(Br)n1C>>COc1nc2ccc(C(O)(c3cnc(C)n3C)c3cnc(C)n3C)cc2c(Cl)c1Cc1ccc(F)cc1,,C1CCOC1,,[Li]CCCC,,test
US20060004068A1,CCN(CC(O)c1ccccc1)c1ccc(C(O[Si](CC)(CC)CC)(C(F)(F)F)C(F)(F)F)cc1>>CCN(CC(O)c1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100249374A1,CCCCCCCCCCCCCCCCCCOC1CC(COc2ccc(C=O)cc2)CC(OCCCCCCCCCCCCCCCCCC)C1OCCCCCCCCCCCCCCCCCC.COc1ccc([Mg]Br)cc1>>CCCCCCCCCCCCCCCCCCOC1CC(COc2ccc(C(O)c3ccc(OC)cc3)cc2)CC(OCCCCCCCCCCCCCCCCCC)C1OCCCCCCCCCCCCCCCCCC,,C1CCOC1,,,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Cc1cc(N)[nH]n1>>COc1ccc2nc(Nc3cc(C)n[nH]3)c3[nH]ncc3c2c1,C1COCCO1,CO,,Cl,,test
US20070167458A1,O=[N+]([O-])c1cccc2c1CCC2O>>O=[N+]([O-])c1cccc2c1CC=C2,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20110076292A1,NNc1ccccc1Cl.O=CNC(=O)c1cn2c(n1)-c1ccc(Br)cc1OCC2>>Clc1ccccc1-n1ncnc1-c1cn2c(n1)-c1ccc(Br)cc1OCC2,,CC(=O)O,,Cl,,test
US20100311693A1,CCOc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3ccc4c(c3)CCNCC4)nc12.CS(=O)(=O)CCCl>>CCOc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3ccc4c(c3)CCN(CCS(C)(=O)=O)CC4)nc12,,CCOC(C)=O,CN(C)C=O,[I-].[K+],O=C([O-])O.[Na+],test
US20070232615A1,CN(C)CCO.CN(Cc1cn2c(F)cccc2n1)[C@H]1CCCc2cccnc21>>CN(C)CCOc1cccc2nc(CN(C)[C@H]3CCCc4cccnc43)cn12,,C1CCOC1,,[H-].[Na+],,test
US05248693,CC(=O)OC(C)=O.CC(O)CC#Cc1ccccc1S(N)(=O)=O>>CC(=O)OC(C)CC#Cc1ccccc1S(N)(=O)=O,,c1ccncc1,,,,test
US20070167443A1,CON(C)C(=O)c1cn(Cc2cccc(Br)n2)c2ccccc2c1=O.COc1ccc([Mg]Br)cc1>>COc1ccc(C(=O)c2cn(Cc3cccc(Br)n3)c3ccccc3c2=O)cc1,,C1CCOC1,,,,test
US20120197014A1,N#CCc1c[nH]c2ccc(Br)cc12.O>>NC(=O)Cc1c[nH]c2ccc(Br)cc12,,CC(C)(C)O,O,Cl,[K+].[OH-],test
US20140296200A1,CCOC(=O)C(=CN(C)C)c1ccc(C#N)cc1.NNc1ccc(C(=O)O)cn1>>N#Cc1ccc(-c2cnn(-c3ccc(C(=O)O)cn3)c2O)cc1,,CC(C)O,,CCN(C(C)C)C(C)C,Cl,test
US20080096877A1,C=CC(=O)CC1CN=C(c2cc3cccc(N(C)S(=O)(=O)c4cccs4)c3[nH]2)S1.CNN>>CN1CCC(CC2CN=C(c3cc4cccc(N(C)S(=O)(=O)c5cccs5)c4[nH]3)S2)=N1,,CCOC(C)=O,,C1CCOC1,,test
US20130178460A1,CC(C)(C)OC(=O)N[C@H]1COCC[C@H]1N.Cc1ccc(NC(=O)c2csc3cnc(Cl)nc23)nc1C>>Cc1ccc(NC(=O)c2csc3cnc(N[C@@H]4CCOC[C@@H]4NC(=O)OC(C)(C)C)nc23)nc1C,,C1COCCO1,ClCCl,CCN(C(C)C)C(C)C,,test
US20130045986A1,CS(=O)(=O)c1ccc(C(=O)O)c(F)c1.Nc1ccc(Br)cc1N>>CS(=O)(=O)c1ccc(-c2nc3cc(Br)ccc3[nH]2)c(F)c1,,CCOC(C)=O,O,[Na+].[OH-],,test
US20100093733A1,COC(=O)/C=C/C1CCC(c2ccc([N+](=O)[O-])cc2)CC1>>COC(=O)CCC1CCC(c2ccc(N)cc2)CC1,[Pd],CCO,,,,test
US20040127536A1,Nc1cccc(-c2nn(C3CCCCO3)c3ccc(-c4ncn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc23)c1.O=C(O)c1ccoc1>>O=C(Nc1cccc(-c2nn(C3CCCCO3)c3ccc(-c4ncn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc23)c1)c1ccoc1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20110257100A1,CC(C)(C)OC(=O)N1CC(OCc2ccc(-c3cc4nccc(Oc5ccc(NC(=O)NC6CC6)cc5F)c4s3)nc2)C1>>O=C(Nc1ccc(Oc2ccnc3cc(-c4ccc(COC5CNC5)cn4)sc23)c(F)c1)NC1CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100292210A1,C=O.Clc1ccc2c(n1)O[C@H](c1ccccc1)CNC2>>CN1Cc2ccc(Cl)nc2O[C@H](c2ccccc2)C1,,CO,,CC(=O)O,,test
US20080188483A1,Cc1ccc(NC(=O)c2ccccc2)cc1Nc1nccn1-c1ncnc2[nH]ccc12>>Cc1ccc(N)cc1Nc1nccn1-c1ncnc2[nH]ccc12,,Cl,,,,test
US20080113981A1,COc1ccc(N)cc1-c1ccccc1.O=N[O-]>>COc1ccc(O)cc1-c1ccccc1,,CC(=O)O,O,O=S(=O)(O)O,,test
US20120115811A1,COC(=O)CBr.Cc1cc(-c2ccc(O)c(NC(=O)[C@H](Cc3ccccc3)NCc3cscn3)c2)ccn1>>COC(=O)COc1ccc(-c2ccnc(C)c2)cc1NC(=O)[C@H](Cc1ccccc1)NCc1cscn1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US08673843B2,COC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C>>COC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1,,C1COCCO1,,Cl,,test
US20140171403A1,O=C(CCCc1c[nH]nn1)NC1CCN(C(=O)/C=C/c2cc(Cl)cc(Cl)c2)CC1>>O=C(CCCc1c[nH]nn1)NC1CCN(C(=O)CCc2cc(Cl)cc(Cl)c2)CC1,[Pt],CCO,,,,test
US20050113392A1,C1CNNC1.CSc1nccc(C(=O)C(Cc2ccccc2Cl)C(=O)OC(C)(C)C)n1>>CSc1nccc(-c2c(Cc3ccccc3Cl)c(=O)n3n2CCC3)n1,,c1ccncc1,,Cl,Cl,test
US20080045555A1,CCCCCNc1nc[nH]c1-c1nc(-c2ccccc2)n[nH]1.O=C(n1ccnc1)n1ccnc1>>CCCCCn1c(=O)n2nc(-c3ccccc3)nc2c2[nH]cnc21,,C1CCOC1,,,,test
US05318966,CCOC(=O)CC1C(=O)CCc2c(OC)cccc21.NCCCCc1ccccc1>>COc1cccc2c1CC[C@H]1[C@@H]2CC(=O)N1CCCCC1CCCCC1,,Cc1ccccc1,,O,,test
US20100240858A1,C=CC(=O)Cl.CC1(C)CC(NC2CC(C)(C)NC(C)(C)C2)CC(C)(C)N1>>C=CC(=O)N(C1CC(C)(C)NC(C)(C)C1)C1CC(C)(C)NC(C)(C)C1,CN(C)c1ccncc1,O,,ClCCl,[Na+].[OH-],test
US20160075686A1,CC(C)(C)OC(=O)N1CC(c2cncc(N3C(=O)c4ccc(Cl)cc4C3(C)C)c2)C1.CCS(=O)(=O)Cl>>CCS(=O)(=O)N1CC(c2cncc(N3C(=O)c4ccc(Cl)cc4C3(C)C)c2)C1,,CO,ClCCl,CC(=O)Cl,,test
US04954518,CN.CS(=O)(=O)Nc1cc2occ(Br)c(=O)c2cc1Oc1ccccc1>>CNc1coc2cc(NS(C)(=O)=O)c(Oc3ccccc3)cc2c1=O,,O,,Cl,,test
US20150111885A1,COc1ccc(-c2cc(N)c(=O)n(C)c2)cc1NS(C)(=O)=O.O=CC1CC1>>COc1ccc(-c2cc(NCC3CC3)c(=O)n(C)c2)cc1NS(C)(=O)=O,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US20140031349A1,Brc1ccc2cocc2c1I.C=CC[Sn](CCCC)(CCCC)CCCC.CCOC(C)=O>>C=CCc1c(Br)ccc2c1COC2=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,[Cl-].[Li+],,test
US20120165312A1,CC(C)(C)[Si](C)(C)OCCN(Cc1ccccc1)C(=O)c1ccncc1F.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)[Si](C)(C)OCCN(Cc1ccccc1)C(=O)c1cc[n+]([O-])cc1F,,C1CCOC1,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US06201024B1,C1CCOC1.NCCO.O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(NCCCl)ccc1Cl>>O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(NCCN2CCCCC2)ccc1Cl,,C1CCOC1,,CCN(CC)CC,,test
US20160211456A1,BrC1=CC2(C3=c4cc5c6ccccc6c6ccccc6c5cc4=CC3=C1)c1ccccc1-c1ccccc12.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(C2=CC3(C4=c5cc6c7ccccc7c7ccccc7c6cc5=CC4=C2)c2ccccc2-c2ccccc23)OC1(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,CC(=O)[O-].[K+],,test
US20050085465A1,CC(=O)N1CCN(CCCO)CC1.COc1cc2ncnc(Cl)c2cc1O>>COc1cc2ncnc(Cl)c2cc1OCCCN1CCN(C(C)=O)CC1,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04531964,CC(C)OC(=O)c1cc(N)c(F)cc1Cl.O=C(Cl)OC(Cl)(Cl)Cl>>CC(C)OC(=O)c1cc(N=C=O)c(F)cc1Cl,,CCOC(C)=O,,,,test
US20140148437A1,Nc1cc(Br)cc2cc[nH]c12.O=C(Cl)C1CC1>>O=C(Nc1cc(Br)cc2cc[nH]c12)C1CC1,,ClCCl,,CCN(CC)CC,,test
US20040157886A1,Nc1ccc2c(c1)NC(=O)CO2.O=C(O)C(=O)N1CCC(Cc2ccccc2)CC1>>O=C1COc2ccc(NC(=O)C(=O)N3CCC(Cc4ccccc4)CC3)cc2N1,,CCOCC,,,,test
US20110046122A1,CC(N)(CO)c1cc(Br)ccc1F.O=C(Cl)C(Br)Cc1ccccc1>>CC(CO)(NC(=O)C=Cc1ccccc1)c1cc(Br)ccc1F,,CC#N,,CCN(CC)CC,,test
US20120094979A1,CCOC(=O)CCCBr.Cc1c(-c2nnc(-c3ccc(OC(C)C)c(C#N)c3)s2)ccc2c1CCNC2>>CCOC(=O)CCCN1CCc2c(ccc(-c3nnc(-c4ccc(OC(C)C)c(C#N)c4)s3)c2C)C1,,CCOC(C)=O,CN(C)C=O,Cl,O=C([O-])[O-].[K+].[K+],test
US20130150343A1,C1CNCCOC1.Fc1ccc2nnc(Cl)n2c1>>Fc1ccc2nnc(N3CCCOCC3)n2c1,,CN1CCCC1=O,,,,test
US20130029973A1,CCOC(=O)C1(N)CC1.COC(=O)c1ccc(CCc2ccc(NC(=O)c3c(NC(=O)c4cccc(S(=O)(=O)Cl)c4)sc4c3CCCC4)cc2)cc1>>CCOC(=O)C1(NS(=O)(=O)c2cccc(C(=O)Nc3sc4c(c3C(=O)Nc3ccc(CCc5ccc(C(=O)OC)cc5)cc3)CCCC4)c2)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20090181968A1,COC(=O)c1nc(OC)cnc1N.Cc1ccc(C(=O)Cl)c2ccccc12>>COC(=O)c1nc(OC)cnc1NC(=O)c1ccc(C)c2ccccc12,CN(C)c1ccncc1,ClC(Cl)Cl,,c1ccncc1,,test
US20090131483A1,CCOC(C)=O.Cc1c(C#CCO)cc(C(=O)NCc2cc(C3CC3)no2)c(=O)n1-c1cccc(C(F)(F)F)c1>>Cc1c(CCC(=O)O)cc(C(=O)NCc2cc(C3CC3)no2)c(=O)n1-c1cccc(C(F)(F)F)c1,[Pd],CCO,,,,test
US20100190824A1,COc1ccc(CC2NCC(=Cc3ccccn3)C(=O)C2(C)C)cc1.Cc1cccc(C)c1N=C=O>>COc1ccc(CC2N(C(=O)Nc3c(C)cccc3C)CC(=Cc3ccccn3)C(=O)C2(C)C)cc1,,Cc1ccccc1,,,,test
US20080004470A1,CC(=O)Cl.CNCCC(O)c1ccccc1>>CC(=O)N(C)CCC(O)c1ccccc1,,O,,CCN(CC)CC,ClCCl,test
US20080045546A1,NCc1ccc2c(c1)OC(F)(F)O2.O=C(Nc1cccc2c1C[C@H](O)CC2)Oc1ccccc1>>O=C(NCc1ccc2c(c1)OC(F)(F)O2)Nc1cccc2c1C[C@H](O)CC2,,CS(C)=O,,,,test
US05728866,CCCCCC1=C(CC(=O)O)CCC1=O.CO>>CCCCC[C@@H]1C(=O)CC[C@@H]1CC(=O)OC,,C1CCOC1,CO,CCN(CC)CC,[H][H],test
US20080269196A1,N#Cc1ccc(-c2csc(NCC3CC3)n2)cn1>>NCc1ccc(-c2csc(NCC3CC3)n2)cn1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080188528A1,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)c2cccn(Cc3ccc4ccccc4n3)c2=O)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2.O=C(O)C(F)(F)F>>N=C(N)NCCC[C@H](NC(=O)c1cccn(Cc2ccc3ccccc3n2)c1=O)C(=O)O.O=C(O)C(F)(F)F,,O,,CC[SiH](CC)CC,,test
US20110263548A1,CC1CNCCC1Oc1cc(=O)n(-c2ccc(C#N)c(F)c2)cc1Cl.Clc1ncc(C2CC2)cn1>>C[C@@H]1CN(c2ncc(C3CC3)cn2)CC[C@@H]1Oc1cc(=O)n(-c2ccc(C#N)c(F)c2)cc1Cl,,CS(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080063814A1,CCOc1ccc(Br)c(F)c1F.O=C1CCC(C2CCC3(CC2)OCCO3)CC1>>CCOc1ccc(C2(O)CCC(C3CCC4(CC3)OCCO4)CC2)c(F)c1F,,C1CCOC1,Cc1ccccc1,[Mg],[Cl-].[NH4+],test
US20130211093A1,CCCCCCCCO.O.[O-][n+]1c(Cl)cccc1Cl>>CCCCCCCCOc1cccc(=O)n1O,,O,,[Na+].[OH-],,test
US20100305133A1,CCCC[Sn](CCCC)(CCCC)c1cncs1.CCOC(=O)CNC(=O)c1c(O)cc(Br)c2nccnc12>>O=C(O)CNC(=O)c1c(O)cc(-c2cncs2)c2nccnc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CO,[Na+].[OH-],,test
US20150126490A1,CS(=O)(=O)CCc1cnc(N)cn1.O=C1CCC(=O)N1Br>>CS(=O)(=O)CCc1cnc(N)c(Br)n1,,CC#N,,,,test
US20150232481A1,Fc1ccc(CCI)c(Br)c1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>Fc1ccc(CC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c(Br)c1.[I-],,Cc1ccccc1,,,,test
US20090221654A1,CCOP(=O)(CC(=O)C1C=C2C=CC=CC2S1)OCC.O=C[C@H]1[C@H](OC(=O)c2ccc(-c3ccccc3)cc2)C[C@@H]2OC(=O)C[C@H]12>>O=C1C[C@@H]2[C@@H](/C=C/C(=O)c3cc4ccccc4s3)[C@H](OC(=O)c3ccc(-c4ccccc4)cc3)C[C@@H]2O1,,C1CCOC1,ClCCl,[Cl-].[Li+],,test
US20090143576A1,C[C@H]1CNCCc2ccc(Cl)cc21.Cl>>C[C@H]1CNCCc2ccc(Cl)cc21.Cl,,O,,,,test
US20100280010A1,CN(C)[C@@H]1CCNC1.COc1ccc([C@H](C)N(Cc2cn3c(F)cccc3n2)[C@H]2CCCc3cccnc32)cc1>>COc1ccc([C@H](C)N(Cc2cn3c(N4CC[C@@H](N(C)C)C4)cccc3n2)[C@H]2CCCc3cccnc32)cc1,,CC#N,,,,test
US20020103229A1,O=C(NCCOc1cccc(-c2n[nH]c3ccc(-c4ncn[nH]4)cc23)c1)OCc1ccccc1>>NCCOc1cccc(-c2n[nH]c3ccc(-c4ncn[nH]4)cc23)c1,[Pd],CO,,O=CO,,test
US20030186971A1,COC(=O)c1ccccc1S.N#Cc1ccncc1>>O=c1nc(-c2ccncc2)sc2ccccc12,,Cc1ccccc1,,CCN(CC)CC,,test
US20160046624A1,CC(C)CC(O)c1c(Oc2cccc(C(F)(F)F)c2)cnc2c1c(=O)n(CCCOC1CCCCO1)c(=O)n2C.O=CO>>CC(C)CCc1c(Oc2cccc(C(F)(F)F)c2)cnc2c1c(=O)n(CCCOC=O)c(=O)n2C,[Zn],O=CO,,,,test
US20120277224A1,CCCc1c(C)n[nH]c1N.COC(=O)CC(=O)c1ccc(OC)cc1>>CCCc1c(C)nn2c(=O)cc(-c3ccc(OC)cc3)[nH]c12,,CC(=O)O,,,,test
US05081131,CSC1=Nc2cccc3cccc1c23.I.NCCCCc1ccncc1>>I.c1cc2c3c(cccc3c1)C(NCCCCc1ccncc1)=N2,,CCO,,,,test
US20130296551A1,O=C1CN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)C(=O)C(Cc2cccc(Cl)c2)CN1>>Nc1ccc(S(=O)(=O)N2CC(=O)NCC(Cc3cccc(Cl)c3)C2=O)cc1,O=[Pt],CO,,,,test
US20150038488A1,COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1N1CCN(C(=O)OC(C)(C)C)CC1.C[C@@H](Oc1nc(Cl)cc2ncn(C(F)F)c12)[C@H]1CNC(=O)C1>>COc1cc(-c2cc3ncn(C(F)F)c3c(O[C@H](C)[C@H]3CNC(=O)C3)n2)ccc1N1CCN(C(=O)OC(C)(C)C)CC1,,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US05962479,CCC(CC)Nc1cc(C)nc(Cl)c1[N+](=O)[O-].Cc1cc(C)c(N)c(C)c1>>CCC(CC)Nc1cc(C)nc(Nc2c(C)cc(C)cc2C)c1[N+](=O)[O-],,CS(C)=O,,,,test
US20150065495A1,C1COCCN1.O=S(=O)(Cl)c1ccc2[nH]c(Cl)nc2c1>>O=S(=O)(c1ccc2[nH]c(Cl)nc2c1)N1CCOCC1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20040209905A1,BrCCBr.CCNC(=O)Nc1cc(C)c(Oc2ccnc3cc(O)c(OC)cc23)cc1C>>CCNC(=O)Nc1cc(C)c(Oc2ccnc3cc(OCCBr)c(OC)cc23)cc1C,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080300276A1,Fc1ccc(C=C2CCNCC2)cc1.O=C(O)c1nc2ccc(O)cc2[nH]1>>O=C(c1nc2ccc(O)cc2[nH]1)N1CCC(=Cc2ccc(F)cc2)CC1,,CC(C)O,,Cl,,test
US20120040954A1,CCOC(=O)c1ccc(N2CCC(O)CC2)cc1.CS(=O)(=O)Cl>>CCOC(=O)c1ccc(N2CCC(OS(C)(=O)=O)CC2)cc1,,ClCCl,,CCN(CC)CC,,test
US07625923B2,CI.COC(=O)[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)CCN1C(=O)OC(C)(C)C>>COC(=O)[C@]1(C)[C@@H](O[Si](C)(C)C(C)(C)C)CCN1C(=O)OC(C)(C)C,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20080064872A1,COC(=O)C(=CC=Cc1ccc(C(C)C)cc1)N=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccccc1>>COC(=O)c1ccc(-c2ccc(C(C)C)cc2)c(-c2ccccc2)n1,,CC#N,,,,test
US05539112,CC(C)(C)C(=O)Nc1cc(OC2CCCCO2)c(F)c(F)c1F.CC=O>>CC(O)c1c(NC(=O)C(C)(C)C)c(F)c(F)c(F)c1OC1CCCCO1,,C1CCOC1,CCCCCC,O,[Li]CCCC,test
US20160237059A1,COC(=O)Cc1nc(C(F)(F)F)c(Cc2ccc(Cl)c(Cl)c2)c(=O)[nH]1.NN>>NNC(=O)Cc1nc(C(F)(F)F)c(Cc2ccc(Cl)c(Cl)c2)c(=O)[nH]1,,C1CCOC1,,O,,test
US20120309738A1,CNc1cc(N2CCC(C(F)(F)F)CC2)c(Cl)cc1N.N#Cc1cc(N=C=S)c(Cl)cc1F>>Cn1c(Nc2cc(C#N)c(F)cc2Cl)nc2cc(Cl)c(N3CCC(C(F)(F)F)CC3)cc21,,CN(C)C=O,,CC(C)N=C=NC(C)C,,test
US06482852B2,CC(C)(C)OC(=O)N[C@H]1CCCCc2cc(OCC3CCCCC3)c(C(N)=O)cc21>>NC(=O)c1cc2c(cc1OCC1CCCCC1)CCCC[C@@H]2N,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110105461A1,CCCN.Cc1ccc(S(=O)(=O)OC[C@H]2COc3ccc(S(=O)(=O)C(F)(F)F)cc3O2)cc1>>CCCNC[C@H]1COc2ccc(S(=O)(=O)C(F)(F)F)cc2O1,,CC#N,,Cl,,test
US20150065519A1,Nc1cc(-c2nc(-c3ccc(NS(=O)(=O)C(F)(F)F)cc3Cl)cs2)ccn1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=S(=O)(Nc1ccc(-c2csc(-c3ccnc(NS(=O)(=O)C(F)(F)F)c3)n2)c(Cl)c1)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US05300693,Cc1ccccc1.O=C(Cl)c1ccc(Cl)cc1>>Cc1ccc(C(=O)c2ccc(Cl)cc2)cc1,,O,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20130023541A1,CCNCc1ccc(CN2CCN(c3ncccc3C(=O)OC(C)C)CC2)cc1.Cc1ncccc1C=O>>CCN(Cc1ccc(CN2CCN(c3ncccc3C(=O)OC(C)C)CC2)cc1)Cc1cccnc1C,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140031360A1,COC(=O)c1c[nH]c2ccc(-c3cncc(OC(C)C)n3)cc12.NN>>CC(C)Oc1cncc(-c2ccc3[nH]cc(C(=O)NN)c3c2)n1,,CCO,,O,,test
US20080004271A1,Nc1cccc(C2OCCO2)c1.O=C=Nc1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc(C(F)(F)F)cc1)Nc1cccc(C2OCCO2)c1,,C1CCOC1,CCCCCC,,,test
US20080114012A1,COS(=O)(=O)c1ccc(C)cc1.Cc1cc(C)cc(NC(=O)N2CC3(CC3)c3c4ccc[nH]c-4nc3C2c2cccc(F)c2)c1>>Cc1cc(C)cc(NC(=O)N2CC3(CC3)c3c4cccn(C)c-4nc3C2c2cccc(F)c2)c1,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20080051418A1,CC(C)Oc1nn(CCCO)cc1C(=O)NCc1ccc(Cl)cc1Cl.CCn1cc(CC(=O)OC)c(O)n1>>CCn1cc(CC(=O)O)c(OCCCn2cc(C(=O)NCc3ccc(Cl)cc3Cl)c(OC(C)C)n2)n1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20160176843A1,CC(C)(C)OC(=O)N1CCC(N(CCc2ccc(Cl)cc2)Cc2cccc(C#N)c2)CC1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1CCC(N(CCc2ccc(Cl)cc2)Cc2cccc(-c3nnn[nH]3)c2)CC1,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US20040122063A1,CCOC(=O)c1cn2cc(Cl)ccc2n1.[Li+]>>O=C([O-])c1cn2cc(Cl)ccc2n1.[Li+],,C1CCOC1,,O,,test
US04649146,CCN1CCCC1CN.CCOC(=O)c1nc(NC)sc1-c1ccncc1>>CCN1CCCC1CNC(=O)c1nc(NC)sc1-c1ccncc1,,OCCO,,Cl,O,test
US20110207704A1,N#Cc1cc(C=O)ccc1F.O>>N#Cc1cc(C(=O)O)ccc1F,,CC(C)(C)O,O,[Na+].[O-]Cl,,test
US05521177,CCCc1nc2c(Cl)cc(N3C(=O)c4ccccc4C3=O)cc2[nH]1.COC(=O)c1ccccc1-c1ccc(CBr)cc1>>CCCc1nc2c(Cl)cc(N3C(=O)c4ccccc4C3=O)cc2n1Cc1ccc(-c2ccccc2C(=O)OC)cc1,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20160235716A1,C[C@H](N)C1CC1.O=Cc1ccc(F)cc1>>C[C@H](NCc1ccc(F)cc1)C1CC1,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04152136,O=C(Cc1ccccc1)Cc1ccccc1.O=CNC(NC=O)NC=O>>O=c1c(-c2ccccc2)c[nH]cc1-c1ccccc1,,O,,CN(C)C=O,,test
US04996318,CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@H](O)C[C@]12C>>CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3C(=O)C[C@]12C,,CC(C)=O,,O=S(=O)(O)O,O=[Cr](=O)=O,test
US20030171377A1,COC(=O)C(Cc1ccc(O)cc1)c1ccccc1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)C(Cc1ccc(S(=O)(=O)C(F)(F)F)cc1)c1ccccc1,,CCOC(C)=O,ClCCl,,,test
US20030225106A1,O=S(Cl)Cl.OCc1ccc2ncccc2c1>>ClCc1ccc2ncccc2c1,,c1ccccc1,,,,test
US20070078164A1,CC(C)(C)OC(=O)N1CC[C@H](c2cccc(-c3cccc(O)c3)c2)[C@@H](OCc2ccc3ccccc3c2)C1.COCCCl.Cl>>COCCOc1cccc(-c2cccc([C@H]3CCNC[C@@H]3OCc3ccc4ccccc4c3)c2)c1.Cl,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20150210687A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Fc1cccc2[nH]nc(I)c12>>CC(C)(C)OC(=O)n1nc(I)c2c(F)cccc21,CN(C)c1ccncc1,C1CCOC1,,,,test
US20020115863A1,CCCC[C@@H](C(=O)OC)[C@H](O)C(=O)OC>>CCCC[C@@H](C(=O)O)[C@H](O)C(=O)O,,CO,O,Cl,[Na+].[OH-],test
US20140206618A1,CC(C)(C)OC(=O)N1CCN[C@@H](CO)C1.N#Cc1c(F)ccc(C2CO2)c1F>>CC(C)(C)OC(=O)N1CCN(CC(O)c2ccc(F)c(C#N)c2F)[C@@H](CO)C1,,CCO,,,,test
US06197960B1,CCOC(=O)CC(c1ccc(F)cc1)C(C#N)C(=O)OCC>>CCOC(=O)[C@@H]1CNC(=O)C[C@H]1c1ccc(F)cc1,[Ni],CCO,,[H][H],,test
US04745113,CCOC(=O)C(C)(SNc1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1F)C(=O)OCC.O=C=NC(=O)c1c(F)cccc1F>>CCOC(=O)C(C)(SN(C(=O)NC(=O)c1c(F)cccc1F)c1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1F)C(=O)OCC,,Cc1ccccc1,,,,test
US20080318968A1,CN(C)C(=O)c1cnc(Cl)cn1.COC(=O)c1cc(O)cc(O[C@@H](C)COC(F)F)c1>>COC(=O)c1cc(Oc2cnc(C(=O)N(C)C)cn2)cc(O[C@@H](C)COC(F)F)c1,,CC#N,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20140343000A1,C=C(C)[C@@H]1CC[C@]2(N=C=O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CC(C)(C)OC(=O)NC1(CN)CC1>>C=C(C)[C@@H]1CC[C@]2(NCC3(NC(=O)OC(C)(C)C)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1CCOC1,,,,test
US20090209476A1,O=C(Cl)Cl.O=C(NNc1ccc(C(F)(F)F)cc1)c1ccc([N+](=O)[O-])cc1>>O=c1oc(-c2ccc([N+](=O)[O-])cc2)nn1-c1ccc(C(F)(F)F)cc1,[Pd],CCO,,[H][H],,test
US20060074075A1,CC(C)(C)C1=CC(=O)C(=O)C(C(C)(C)C)=C1.O=[N+]([O-])O>>CC(C)(C)C1=CC(C(C)(C)C)=C([N+](=O)[O-])C(=O)C1=O,,CC(=O)O,,O,,test
US20120329785A1,CCOc1ccccc1N.COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1>>CCOc1ccccc1Nc1nc2ccc(OC)cc2c2c[nH]nc12,C1COCCO1,CO,,Cl,,test
US20100249071A1,CC(C)N.CCOC(=O)c1cc(C)nc(Cl)c1>>CCOC(=O)c1cc(C)nc(NC(C)C)c1,,C1COCCO1,,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20050222230A1,COC(OC)N(C)C.COc1ccc(CC(C)=O)cc1.NN>>COc1ccc(-c2cn[nH]c2C)cc1,,CCO,,O,,test
US20100152455A1,O=Cc1ccc(Br)cc1O.OB(O)c1ccccc1>>O=Cc1ccc(-c2ccccc2)cc1O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20110034334A1,CC(C)(C)C(=O)Oc1c(-c2c(F)ccc(F)c2Cl)c(=O)[nH]c2ncccc12.FC(F)CBr>>O=c1c(-c2c(F)ccc(F)c2Cl)c(O)c2cccnc2n1CC(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070043044A1,CCOC(=O)c1cc2c(Cl)nc(N)nc2s1.OCc1ccccc1>>Nc1nc(OCc2ccccc2)c2cc(C(=O)O)sc2n1,,C1CCOC1,,[H-].[Na+],,test
US05698560,C[Mg]Br.N#Cc1ccccc1C=O>>CC(O)c1ccccc1C#N,,C1CCOC1,,O,,test
US20040072829A1,C=CCN1CCNCC1.COc1ccc(CCNc2nc(Cl)nc(N(C)CCCc3ccc(Cl)cc3)n2)cc1>>C=CCN1CCN(c2nc(NCCc3ccc(O)cc3)nc(N(C)CCCc3ccc(Cl)cc3)n2)CC1,,CC#N,ClCCl,BrB(Br)Br,O=C([O-])O.[Na+],test
US20030078282A1,CC1(c2cccc(O)c2)CCNCC1.CCCCCCBr>>CCCCCCN1CCC(C)(c2cccc(O)c2)CC1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20050113387A1,CC(C)n1cc(-c2nc(Br)c(N)nc2-c2ccccc2)ccc1=O.Oc1ccccc1>>CC(C)n1cc(-c2nc(Oc3ccccc3)c(N)nc2-c2ccccc2)ccc1=O,,CN1CCCC1=O,O,CCOC(C)=O,[H-].[Na+],test
US20080181866A1,Cn1ccnc1[C@H]1SCC(C(=O)O)N1C(=O)OCc1ccccc1.Nc1nc(-c2ccc(C(=O)NC3CC3)cc2)cs1>>Cn1ccnc1[C@H]1SCC(C(=O)Nc2nc(-c3ccc(C(=O)NC4CC4)cc3)cs2)N1C(=O)OCc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160222033A1,CCN(Cc1cc(=O)n2c(C3CC3C(N)=O)c(C)sc2n1)c1ccc(F)cc1>>CCN(Cc1cc(=O)n2c(C3CC3C#N)c(C)sc2n1)c1ccc(F)cc1,,C1CCOC1,,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US20150291595A1,COc1cc(N)cc(B2OC(C)(C)C(C)(C)O2)c1.Cc1ccn2nc([C@H](C)Nc3ncnc4c3c(Br)cn4COCC[Si](C)(C)C)n(-c3ccccc3)c(=O)c12>>COc1cc(N)cc(-c2cn(COCC[Si](C)(C)C)c3ncnc(N[C@@H](C)c4nn5ccc(C)c5c(=O)n4-c4ccccc4)c23)c1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150065468A1,CNCc1nn(C2CCCCO2)c2ncc(-c3ccc(CC(=O)Nc4cc(C(C)(C)C)on4)c(F)c3)cc12>>CNCc1n[nH]c2ncc(-c3ccc(CC(=O)Nc4cc(C(C)(C)C)on4)c(F)c3)cc12,,C1COCCO1,,Cl,,test
US20040229876A1,CC(C)(C)c1csc(N)n1.COc1cc2nccc(Oc3ccc(N)c(F)c3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)Nc4nc(C(C)(C)C)cs4)c(F)c3)c2cc1OC,,ClC(Cl)Cl,O,CCN(CC)CC,,test
US20050234057A1,COC(=O)C1(NC(=O)c2cc3ccccc3o2)CCCCC1>>O=C(NC1(C(=O)O)CCCCC1)c1cc2ccccc2o1,,CO,O,[Na+].[OH-],,test
US06002008,N#Cc1cnc2ccc([N+](=O)[O-])cc2c1Cl.Nc1cccc(F)c1>>N#Cc1cnc2ccc([N+](=O)[O-])cc2c1Nc1cccc(F)c1,,CCOC(C)=O,,C,,test
US20080139631A1,Cc1cc2c(C(F)(F)F)c(C#N)ccc2[nH]1.N#CCBr>>Cc1cc2c(C(F)(F)F)c(C#N)ccc2n1CC#N,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110207701A1,CC(=O)OCc1cccc(CCCCO)c1Br>>CC(=O)OCc1cccc(CCCC=O)c1Br,,ClCCl,,CS(C)=O,O=C(Cl)C(=O)Cl,test
US20070167443A1,COC=C(C(=O)OC)C(=O)c1ccc(C)c(C)c1.Cc1ccncc1N>>Cc1ccc(C(=O)c2c[nH]c3c(C)ccnc3c2=O)cc1C,,c1ccc(Oc2ccccc2)cc1,,,,test
US05232940,BrC(Br)Br.N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1[N+](=O)[O-]>>N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(Br)c1[N+](=O)[O-],,CC#N,,CC(C)(C)ON=O,,test
US20030007927A1,COC(=O)CCc1c(O)cccc1OCCCCCO.O=C(NCCOCCOCCOCCI)OCc1ccccc1>>COC(=O)CCc1c(OCCCCCO)cccc1OCCOCCOCCOCCNC(=O)OCc1ccccc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040132727A1,CCN(CC)CC.COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2ncnc(Oc3ccc(NC(=O)OCCCCN(C)C)cc3)c2cc1OC,,ClCCl,,Cc1ccccc1,,test
US05597848,CO.O=C(O)CCCc1ccc(C(=O)CCCc2ccccc2)cc1>>COC(=O)CCCc1ccc(C(=O)CCCc2ccccc2)cc1,,O=S(=O)(O)O,,,,test
US20140010783A1,C[Si](C)(C)C#Cc1ccc([N+](=O)[O-])cc1Cl>>C[Si](C)(C)C#Cc1ccc(N)cc1Cl,[Fe],CO,O,[Cl-].[NH4+],,test
US20040102509A1,C=O.CCCCN.O=C1Nc2ccccc2/C1=C/c1ccc[nH]1>>CCCCNCN1C(=O)C(=Cc2ccc[nH]2)c2ccccc21,,CCO,,CCCCCC,,test
US05770617,CCCC[Sn](Cl)(CCCC)CCCC.Clc1ccc(Br)cc1>>CCCC[Sn](CCCC)(CCCC)c1ccc(Cl)cc1,,C1CCOC1,,[Li]CCCC,,test
US20150297586A1,ClCCCn1cnc2ccccc21.c1ccc(N2CCNCC2)cc1>>c1ccc(N2CCN(CCCn3cnc4ccccc43)CC2)cc1,,CC#N,,CCN(C(C)C)C(C)C,[I-].[K+],test
US20150065468A1,BrCc1ccccc1.COc1cc([N+](=O)[O-])c(N)cc1O>>COc1cc([N+](=O)[O-])c(N)cc1OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080181866A1,Cn1ccnc1[C@@H]1NC(C(=O)O)CS1.O=C(Cl)OCc1ccccc1>>Cn1ccnc1C1SCC(C(=O)O)N1C(=O)OCc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04057638,COC(=O)N=C=O.Nc1nc2ccccc2s1>>COC(=O)NC(=O)Nc1nc2ccccc2s1,,ClCCl,,,,test
US04607041,C1CCNCC1.CCCCCC(=O)O.CCOC(C)=O.COC(=O)CC(=O)c1ccccc1.O=Cc1cccc2nonc12>>COC(=O)C1C(c2cccc3nonc23)C(C(=O)OC(C)C)=C(C)NC1(O)c1ccccc1,,CCOC(C)=O,,c1ccccc1,,test
US20050267105A1,CSCCC=O.OCCO>>CSCCC1OCCO1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US06833387B1,COC(=O)CCC(=O)C(=O)OC.NNc1ccccc1>>COC(=O)Cc1c(C(=O)OC)[nH]c2ccccc12,,CO,,CC(=O)O,,test
US05439925,C=CCOC(=O)c1ccc(CO)cc1.CC(O)=S>>C=CCOC(=O)c1ccc(CSC(C)=O)cc1,,C1CCOC1,O,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140187588A1,C=C(C)CO[C@H]1[C@H](C)OC(=O)[C@@H](NC(=O)c2nccc(OC)c2O)CCC[C@@H]1OCC(=C)C.CC(C)C(=O)OCCl>>C=C(C)CO[C@H]1[C@H](C)OC(=O)[C@@H](NC(=O)c2nccc(OC)c2OCOC(=O)C(C)C)CCC[C@@H]1OCC(=C)C,,CC(C)=O,,[I-].[Na+],,test
US20080262042A1,CN(Cc1cc(-c2cccnc2C#N)n(S(=O)(=O)c2ccco2)c1)C(=O)OC(C)(C)C.Cl>>CNCc1cc(-c2cccnc2C#N)n(S(=O)(=O)c2ccco2)c1.Cl,,CC(C)O,CCOC(C)=O,,,test
US05250527,O=S(Cl)Cl.OCc1nccc(N2CCOCC2)c1F>>Cl.Fc1c(N2CCOCC2)ccnc1CCl,,ClC(Cl)Cl,,CCOCC,,test
US20040058965A1,CCCc1oc(-c2ccccc2)nc1CO.O=S(Cl)Cl>>CCCc1oc(-c2ccccc2)nc1CCl,,Cc1ccccc1,,,,test
US20100331293A1,Cc1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2cc(F)cc(F)c2c1Cl.O=C(O)C(F)(F)F>>Cc1c(N2CCNCC2)nc2cc(F)cc(F)c2c1Cl.O=C(O)C(F)(F)F,,ClCCl,,,,test
US06350749B1,CCCn1ccc2c1CC(c1ccccc1)CC2=O.Cl.N=C(N)NN>>CCCn1ccc2c1CC(c1ccccc1)CC2=NNC(=N)N.Cl,,CCO,,Cl,O,test
US20080280928A1,COC(=O)CC(=O)CC(=O)OC.N#CCC(=O)O>>COC(=O)CC(=CC#N)CC(=O)OC,,Cc1ccccc1,,CC(=O)O,,test
US20150238558A1,CI.COC(=O)c1ccc(CN(C(=O)[C@@H]2Cc3ccccc3CN2C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(C)(C)S)[C@H](C)c2ccccc2F)cc1>>COC(=O)c1ccc(CN(C(=O)[C@@H]2Cc3ccccc3CN2C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(C)(C)SC)[C@H](C)c2ccccc2F)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150274661A1,O=C(Nc1cccc(F)c1)c1cc2cc(C3CCN(Cc4ccccc4)C3)ccc2[nH]1>>O=C(Nc1cccc(F)c1)c1cc2cc(C3CCNC3)ccc2[nH]1,[Pd],CO,,,,test
US20160096827A1,CC(C)(C)OC(=O)N1CC[C@@H](Oc2ccc(-c3ncnc(Nc4ccc(N5CCN(C6COC6)CC5)cc4)n3)cc2C#N)C1>>N#Cc1cc(-c2ncnc(Nc3ccc(N4CCN(C5COC5)CC4)cc3)n2)ccc1O[C@@H]1CCNC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US06329405B1,C[C@@H](N)c1ccc(F)c(F)c1.O=C(c1ccc(Cl)cc1)c1cccc([N+](=O)[O-])c1>>C[C@@H](NC(c1ccc(Cl)cc1)c1cccc([N+](=O)[O-])c1)c1ccc(F)c(F)c1,Cl[Ti](Cl)(Cl)Cl,CC(=O)O,,Cl,[BH3-]C#N.[Na+],test
US20080153852A1,Cc1cscc1-c1ccccc1C(O)C(F)(F)F.Nc1nc(Cl)cc(Cl)n1>>Cc1cscc1-c1ccccc1C(Oc1cc(Cl)nc(N)n1)C(F)(F)F,,CCOC(C)=O,,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US20120208791A1,N=C(NN)c1ccn2ccnc2c1.O=CC=O>>c1cnc(-c2ccn3ccnc3c2)nn1,,CCO,,,,test
US20110245245A1,C1COCCN1.O=C(Cn1c(=O)[nH]c2ncc(Br)nc21)N1CCOCC1.O=C(O)Cn1c(=O)[nH]c2ncc(Br)nc21.O=C(n1ccnc1)n1ccnc1>>O=C(Cn1c(=O)[nH]c2ncc(-c3ccc(-c4nnc[nH]4)cc3)nc21)N1CCOCC1,,CN(C)C=O,ClCCl,O=C(O)C(F)(F)F,,test
US20110112151A1,Cn1ccnc1SCC(=O)C1(c2ccc(Cl)cc2)CC1.O=C(OO)c1cccc(Cl)c1>>Cn1ccnc1S(=O)CC(=O)C1(c2ccc(Cl)cc2)CC1,,ClCCl,,,,test
US20150274691A1,Cc1cc(C)c(-c2c(OC(=O)C(C)(C)C)cc(CCOS(C)(=O)=O)oc2=O)c(C)c1.Fc1cccc(S)c1>>Cc1cc(C)c(-c2c(O)cc(CCSc3cccc(F)c3)oc2=O)c(C)c1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US04938794,CCOC(=O)c1nn(-c2ccc(OC(F)(F)F)cc2)c2cccc(OC(F)F)c2c1=O>>O=C(O)c1nn(-c2ccc(OC(F)(F)F)cc2)c2cccc(OC(F)F)c2c1=O,,O,,CCO,[Na+].[OH-],test
US20140329794A1,NC[C@H](O)CN1CCc2ccccc2C1.O=C(O)c1ccccc1>>O=C(NC[C@H](O)CN1CCc2ccccc2C1)c1ccccc1,,ClCCl,O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20080312226A1,Cc1sc(N2CCNCC2)nc1-c1ccccc1.O=C(Nc1cccnc1)OCC(Cl)(Cl)Cl>>Cc1sc(N2CCN(C(=O)Nc3cccnc3)CC2)nc1-c1ccccc1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US06583156B1,CC(C)(C)[Si](C)(C)OCc1cccc(C(O)c2cc(C(F)(F)F)nc3c(C(F)(F)F)cccc23)c1>>OCc1cccc(C(O)c2cc(C(F)(F)F)nc3c(C(F)(F)F)cccc23)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120071479A1,CC(NC(=O)OCc1ccccc1)C(=O)O.CCCN(CCC)C(=O)CCl>>CCCN(CCC)C(=O)COC(=O)CCNC(=O)OCc1ccccc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130116233A1,CCOC(=O)c1c(Cl)cncc1/C=N/NC(C)=O>>O=c1[nH]ncc2cncc(Cl)c12,,C1COCCO1,,[Na+].[OH-],,test
US20080269300A1,CC1(C)OCC(CO)O1.O=Cc1ccc(O)cc1>>CC1(C)OCC(COc2ccc(C=O)cc2)O1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100029643A1,CS(=O)(=O)Nc1ccc(C(F)(F)F)cn1.O=[N+]([O-])O>>CS(=O)(=O)Nc1ncc(C(F)(F)F)cc1[N+](=O)[O-],,CC(=O)O,,,,test
US20140256700A1,CI.COc1ccc(COC(=O)Nc2ccc3c(c2)c2c(C(N)=O)cc(Br)cc2n3Cc2ccccc2)cc1>>COc1ccc(COC(=O)N(C)c2ccc3c(c2)c2c(C(N)=O)cc(Br)cc2n3Cc2ccccc2)cc1,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100190747A1,CCOCCCOc1nc2[nH]ccc2c(=O)n1-c1ccc(OCC(F)(F)F)cc1.O=Ic1ccccc1>>CCOCCCOc1nc2c(c(=O)n1-c1ccc(OCC(F)(F)F)cc1)CC(=O)N2,,CC(=O)O,,,,test
US20040006050A1,CC[C@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(Cl)cc1.CI>>CC[C@H](C)[C@@H](CO)N(C)S(=O)(=O)c1ccc(Cl)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05965555,C#CCN([Si](C)(C)C)[Si](C)(C)C.CCCn1cnc2c1c(=O)n(CCCCC(C)=O)c(=O)n2C>>CCCn1cnc2c1c(=O)n(CCCCC(C)(O)C#CCN)c(=O)n2C,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20100210619A1,Cc1cc(O)ccc1N.O=C(O)c1cc(NC2CCCCC2)ncn1>>Cc1cc(O)ccc1NC(=O)c1cc(NC2CCCCC2)ncn1,,CN(C)C=O,,CCN(CC)CC,ClCCl,test
US20160200704A1,CC(C)[Si](C(C)C)(C(C)C)n1ccc2c(F)cccc21.CN(C)C=O>>CC(C)[Si](C(C)C)(C(C)C)n1ccc2c(F)c(C=O)ccc21,,C1CCOC1,,[Li]C(C)CC,,test
US20020032227A1,CON=C(c1cc(C)no1)c1ccccc1CO.O=S(Cl)Cl>>CON=C(c1cc(C)no1)c1ccccc1CCl,,c1ccccc1,,,,test
US20090036492A1,BrP(Br)Br.CN(C)C=O.O=C1CCc2ccc(Cl)cc2C1>>O=CC1=C(Br)CCc2ccc(Cl)cc21,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20100316601A1,CC(C)(C)OC(=O)NN(C(=O)OC(C)(C)C)c1ccc2c(c1)C(C)(C)CC2.CCOC(=O)CC(C)=O>>CC1=NN(c2ccc3c(c2)C(C)(C)CC3)C(=O)C1,,CC(=O)O,,O=C(O)C(F)(F)F,,test
US20150259354A1,NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c1NCc1ccc([N+](=O)[O-])cc1-2>>NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c1NCc1ccc(N)cc1-2,[Pd],CO,ClCCl,,,test
US20100152235A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCN(C(=O)OC(C)(C)C)C4)no2)cc1C#N.Cl>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCNC4)no2)cc1C#N.Cl,,C1COCCO1,,,,test
US20140179676A1,CB1OB(C)OB(C)O1.COc1cc(C=O)c(Br)cc1Cl>>COc1cc(C=O)c(C)cc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20050143329A1,CN(C)N.O=Cc1c(Cl)n([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2cc(Cl)c(Cl)cc12>>CN(C)N=C=C1c2cc(Cl)c(Cl)cc2N([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C1Cl,,CN(C)C=O,CO,ClC(Cl)Cl,,test
US20160176817A1,CCOC(=O)C(=O)c1cc(C(=O)Nc2ccc(F)c(C)c2)n(C)c1.CC[C@@H](C)N>>CC[C@@H](C)NC(=O)C(=O)c1cc(C(=O)Nc2ccc(F)c(C)c2)n(C)c1,,CCO,,,,test
US20070072900A1,BrCCBr.O=[N+]([O-])c1ccc(S)cc1>>O=[N+]([O-])c1ccc(SCCBr)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05679696,O=C(O)c1ccc(OC(F)F)c(OC2CCCC2)c1.O=S(Cl)Cl>>O=C(Cl)c1ccc(OC(F)F)c(OC2CCCC2)c1,,Cc1ccccc1,,,,test
US20020193402A1,CCOC(=O)[C@]1(F)C[C@@]2(c3ccccc3)C(=O)C=C[C@@H]1N2Cc1ccccc1>>CCOC(=O)[C@]1(F)C[C@@]2(c3ccccc3)C(=O)CC[C@@H]1N2Cc1ccccc1,[Pd],ClCCl,,CCOC(C)=O,,test
US20160031847A1,CC(C)(C)OC(=O)CN.CC(C)(C)OC(=O)Cc1cc(C=O)cs1>>CC(C)(C)OC(=O)CNCc1csc(CC(=O)OC(C)(C)C)c1,,CC(=O)O,ClCCl,O=C([O-])O.[Na+],,test
US05045561,O=C(O)c1cc(=O)c2ccoc2s1.O=C(n1ccnc1)n1ccnc1>>CN(C)C(=O)c1cc(=O)c2ccoc2s1,,C1CCOC1,,,,test
US04017538,CSc1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1.O=P(Cl)(Cl)Cl>>CSc1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1,,CN(C)C=O,,,,test
US20120083605A1,CCOC(=O)C(C(=O)OCC)c1ncccc1C(F)(F)F>>CCOC(=O)Cc1ncccc1C(F)(F)F,,O,,CS(C)=O,[Cl-].[Na+],test
US20070161574A1,CCOC(=O)C12CC1C=CCCCCNC(=O)N1CC(Oc3cc(-c4ccccc4)nc4cc(OC)ccc34)CC1C(=O)N2>>COc1ccc2c(OC3CC4C(=O)NC5(C(=O)O)CC5C=CCCCCNC(=O)N4C3)cc(-c3ccccc3)nc2c1,,CO,,[Na+].[OH-],,test
US04273773,CCOC(CN)OCC.COC(=O)c1ccccc1C=C(C)[N+](=O)[O-]>>CCOC(CN1C(=O)c2ccccc2C1C(C)[N+](=O)[O-])OCC,,CC#N,,CC(=O)[O-].[Na+],,test
US20100256188A1,Cn1c(Nc2cc(CN)c(F)cc2Cl)nc2cc(C(=O)N[C@@H]3CC[C@@H](C(F)(F)F)CC3)c(OCC(F)F)cc21.O=C(O)C1(C(F)(F)F)CC1>>Cn1c(Nc2cc(CNC(=O)C3(C(F)(F)F)CC3)c(F)cc2Cl)nc2cc(C(=O)N[C@@H]3CC[C@@H](C(F)(F)F)CC3)c(OCC(F)F)cc21,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US06297250B1,C1CCOC1.CC(C)CO.Clc1nc(N2CCCCC2)c2nc(Cl)nc(N3CCCCC3)c2n1.O>>CC(C)COc1nc(N2CCCCC2)c2nc(OCC(C)C)nc(N3CCCCC3)c2n1,,C1CCOC1,,[Na],,test
US05654297,Cc1ccc(F)cc1C(=O)Cl.Nc1ccc(C(=O)N2CCC=Cc3sccc32)c(Cl)c1>>Cc1ccc(F)cc1C(=O)Nc1ccc(C(=O)N2CCC=Cc3sccc32)c(Cl)c1,,ClCCl,O,CCN(CC)CC,,test
US06235731B1,CS(=O)(=O)Cl.OC[C@@H]1COc2ccccc2O1>>CS(=O)(=O)OC[C@@H]1COc2ccccc2O1,,CCOCC,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20090105253A1,CCCC(=O)CC(=O)OCC.[N-]=[N+]=Nc1ccc2c(c1)CCNC2=O>>CCCc1c(C(=O)O)nnn1-c1ccc2c(c1)CCNC2=O,,CCO,,C,C[O-].[Na+],test
US20070054916A1,Cc1ccc(C(=O)O)cc1B1OC(C)(C)C(C)(C)O1.Nc1ncc2cc(Br)ccc2n1>>Cc1ccc(C(=O)O)cc1-c1ccc2nc(N)ncc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US05387709,CCOC(=O)Cc1ccc(CC2CCCC2=NO)cc1>>CCOC(=O)Cc1ccc(CC2CCCC2N)cc1,[Ni],CCO,O,N,[H][H],test
US20120232051A1,COc1cc(F)c(F)cc1B(O)O.COc1cc(F)ccc1-c1ccncc1N(CC(F)F)C(=O)c1cc(C(F)(F)F)nc(C(F)(F)F)c1>>COc1cc(F)c(F)cc1-c1ccncc1NCC(F)F,,CCCCCCC,CCOC(C)=O,,,test
US20080280956A1,CC(C)S(=O)NCc1cccnc1S(=O)(=O)c1ccc(/C=C/c2ccc(F)cc2)cc1>>NCc1cccnc1S(=O)(=O)c1ccc(/C=C/c2ccc(F)cc2)cc1,,CO,,Cl,,test
US20090306042A1,CC(C)(C)OC(=O)N1CCCC[C@H]1C(=O)N[C@H](C#N)Cc1ccc(-c2ccc(C#N)nc2)cc1>>N#Cc1ccc(-c2ccc(C[C@@H](C#N)NC(=O)[C@@H]3CCCCN3)cc2)cn1,,O=CO,,,,test
US20160176868A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCCOC(=O)C[C@@H](N)c1ccc(F)c(F)c1>>CC(C)(C)OC(=O)N[C@H](CC(=O)O)c1ccc(F)c(F)c1,,C1CCOC1,,CCN(CC)CC,,test
US20150065550A1,COC(=O)CS.CS(=O)(=O)OCCc1ccccc1Br>>COC(=O)CSCCc1ccccc1Br,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US04904690,CO.O=C(O)Cc1cccc2c(=O)cc(C3=CCCCC3)oc12>>COC(=O)Cc1cccc2c(=O)cc(C3=CCCCC3)oc12,,O,,O=S(=O)(O)O,,test
US05075433,COC(=O)CCCCCCCCCCCO[C@@H]1O[C@H](C(=O)OC)[C@@H](OC(C)=O)[C@H](OCc2ccccc2)[C@H]1OC(C)=O>>COC(=O)CCCCCCCCCCCO[C@@H]1O[C@H](C(=O)OC)[C@@H](OC(C)=O)[C@H](O)[C@H]1OC(C)=O,[Pd],CO,,,,test
US20020111358A1,C1CCOC1.COCOc1cccc2sccc12.O>>COCOc1cccc2sc(C(=O)O)cc12,,CCCCCC,,Cl,[Li]CCCC,test
US20080227782A1,COC(=O)c1cnc(-c2ccncc2)nc1>>O=C(O)c1cnc(-c2ccncc2)nc1,,CO,,[Li+].[OH-],,test
US20090099160A1,Cc1c(Br)cccc1C(=O)O.NC1CC1>>Cc1cc(Br)ccc1C(=O)NC1CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050065099A1,Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2>>Cc1c(C)c2c(c(C)c1O)CCC(C)(CO)O2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04512992,CCOC(=O)C(=Cc1ccc(OC)c(OC)c1)C(C)=O>>CCOC(=O)C(Cc1ccc(OC)c(OC)c1)C(C)=O,[Pd],CCOC(C)=O,,,,test
US20030078249A1,CI.COC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C>>COC(=O)[C@]1(C)CCCN1C(=O)OC(C)(C)C,,C1CCOC1,CCCCCC,CC(C)NC(C)C,[Li]CCCC,test
US20100008866A1,CC1(C)OB(C2=CCC(C(F)(F)F)CC2)OC1(C)C.Cn1cnc2c(=O)n(-c3ccc(F)cc3)c(Cl)nc21>>Cn1cnc2c(=O)n(-c3ccc(F)cc3)c(C3=CCC(C(F)(F)F)CC3)nc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140120538A1,COc1ccc(-c2cnc(N)c(Cc3ccccc3)n2)cc1.COc1cccc(C(=O)Cl)c1>>COc1ccc(-c2cnc(NC(=O)c3cccc(OC)c3)c(Cc3ccccc3)n2)cc1,CN(C)c1ccncc1,c1ccncc1,,O,,test
US20040133011A1,COC(=O)C12CCC(CCC(=O)O)(CC1)CC2>>COC(=O)C12CCC(CCCO)(CC1)CC2,,C1CCOC1,,B,Cl,test
US20070232583A1,CC(C)(N)CO.Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccnc(-c3cccc(S(=O)(=O)Cl)c3)c2)n1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccnc(-c3cccc(S(=O)(=O)NC(C)(C)CO)c3)c2)n1,,C1CCOC1,CCOC(C)=O,,,test
US20150322051A1,C=C[C@H](Cc1ccccc1)[C@@H](CCCC)[C@H](C)O.CC(=O)OC(C)=O>>C=C[C@H](Cc1ccccc1)[C@@H](CCCC)[C@H](C)OC(C)=O,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20040242660A1,Nc1ccc(N2C[C@H](CNC(=O)c3ccc(Cl)s3)OC2=O)cc1.O=C(Cl)CCCCCl>>O=C(CCCCCl)Nc1ccc(N2C[C@H](CNC(=O)c3ccc(Cl)s3)OC2=O)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20140206663A1,CC(C)(C)OC(=O)N1CC(=O)C1.CC1C(=O)N(COCC[Si](C)(C)C)N=C2COc3cc(OCc4ccccc4)c(N)cc3N21>>CC1C(=O)NN=C2COc3cc(OCc4ccccc4)c(NC4CN(C(=O)OC(C)(C)C)C4)cc3N21,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US20060040972A1,NN.O=C(CCCc1ccccc1)c1c(O)c2cccnc2n(-c2ccccc2)c1=O>>O=c1c2c(CCCc3ccccc3)n[nH]c2c2cccnc2n1-c1ccccc1,,CN(C)C=O,,O,O,test
US05990116,CI.COc1ccc(OC)c(CCc2ccc3nc[nH]c(=O)c3c2)c1>>COc1ccc(OC)c(CCc2ccc3ncn(C)c(=O)c3c2)c1,,CN(C)C=O,,[H-].[Na+],,test
US20120196864A1,COc1ccc(C=O)cc1O.FC(F)(F)c1ccc(CBr)c(C(F)(F)F)c1>>COc1ccc(C=O)cc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US05710139,COP(=O)(Cc1cc2cc(Cl)ccc2nc1C)OC.O=C1CCC(=O)N1Br>>COP(=O)(Cc1cc2cc(Cl)ccc2nc1CBr)OC,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US06350892B1,COC(=O)COc1ccc(CCCO)cc1.CS(=O)(=O)Cl>>COC(=O)COc1ccc(CCCOS(C)(=O)=O)cc1,,ClCCl,,CCN(CC)CC,,test
US20050054851A1,CC(C)(C)Cn1c(CBr)cc2cnc(C#N)nc21.NNC(=O)c1ccccc1C(=O)NN>>CC(C)(C)Cn1c(Cn2[nH]c(=O)c3ccccc3c2=O)cc2cnc(C#N)nc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05523302,CCCCI.O=Cc1ccc(O)c(C(=O)O)c1>>CCCCOC(=O)c1cc(C=O)ccc1O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130267513A1,Cc1cc2[nH]nc(I)c2c(Cl)n1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1cc2c(c(Cl)n1)c(I)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1,,O,,CCN(CC)CC,ClCCl,test
US20060287291A1,CC1CN(C(=O)OC(C)(C)C)CCN1Cc1cc([N+](=O)[O-])cc2ccoc12>>CC1CN(C(=O)OC(C)(C)C)CCN1Cc1cc(N)cc2ccoc12,[Ni],C1CCOC1,CCO,NN,O,test
US20040106655A1,BrBr.CC(C)Oc1ccc(N)cc1>>CC(C)Oc1ccc(N)c(Br)c1,,CC(=O)O,,,,test
US20100029753A1,CCC(C)(C)c1ccc(S(=O)(=O)Nc2ccsc2C(=O)OC)cc1>>CCC(C)(C)c1ccc(S(=O)(=O)Nc2ccsc2C(=O)O)cc1,,CO,,[Na+].[OH-],,test
US20160108027A1,CC1CCC(CC2(O)CC2)NC1.COc1cc(C(=O)O)cc2nc(NCc3cc(Cl)ccn3)oc12>>COc1cc(C(=O)N2CC(C)CCC2CC2(O)CC2)cc2nc(NCc3cc(Cl)ccn3)oc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05236950,CCSC/C=C(\C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C.O=C(OO)c1cccc(Cl)c1>>CCS(=O)C/C=C(\C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C,,ClCCl,,,,test
US08114894B2,CC(C)(C)OC(=O)N1CCC(N)CC1.CC(C)n1ccc2ccccc21.O=C(Cl)C(=O)Cl>>CC(C)n1cc(C(=O)C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)c2ccccc21,,CCOCC,ClCCl,CCN(CC)CC,,test
US05854272,CCCC=O.c1ccc(COC[C@H]2NC[C@@H](OCc3ccccc3)[C@@H]2OCc2ccccc2)cc1>>CCCCN1C[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1COCc1ccccc1,,CCOCC,CO,Cl,[BH3-]C#N.[Na+],test
US05563162,CNC.O=C(Cl)c1cccc([N+](=O)[O-])c1>>CN(C)C(=O)c1cccc([N+](=O)[O-])c1,,C1COCCO1,,CCOC(C)=O,,test
US20080312286A1,N#Cc1ccc(CBr)cc1.O=C1c2c(cc(O)c(Cl)c2Cl)CC1C1CCCC1>>N#Cc1ccc(C(=O)Oc2cc3c(c(Cl)c2Cl)CC(C2CCCC2)C3)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150266868A1,Cc1nc(CN2CCN(c3c(Cl)cnc(N)c3[N+](=O)[O-])CC2)no1.Cc1nn(C)cc1C=O>>Cc1nc(CN2CCN(c3c(Cl)cnc4[nH]c(-c5cn(C)nc5C)nc34)CC2)no1,,CCO,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20100035883A1,CNC.O=Cc1cccc(C2c3n[nH]c(=O)c4cccc(c34)NC2c2ccccc2)c1>>CN(C)Cc1cccc(C2c3n[nH]c(=O)c4cccc(c34)NC2c2ccccc2)c1,,CO,,[BH4-].[Na+],,test
US20080221335A1,C=CCBr.c1ccc(P(c2ccccc2)c2cccc(-c3cc[nH]n3)c2)cc1>>C=CCn1ccc(-c2cccc(P(c3ccccc3)c3ccccc3)c2)n1,,C1CCOC1,,[H][H],[H-].[Na+],test
US04705782,COc1cc2c(cc1OC)CCC(C(=O)NO)=C2.[Na]>>COc1cc2c(cc1OC)CCC(C(=O)NO)=C2.[Na],,CO,,,,test
US20150353499A1,C[C@@H](C(=O)N[C@H]1CCc2ccccc2N(Cc2c(C#CC3(O)COC3)ccc3ccccc23)C1=O)N(C)C(=O)OC(C)(C)C>>CN[C@@H](C)C(=O)N[C@H]1CCc2ccccc2N(Cc2c(C#CC3(O)COC3)ccc3ccccc23)C1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060183792A1,CCC(N)CC.COC(=O)Cc1c(Br)csc1-c1ccc(C(=O)O)cc1>>CCC(CC)NC(=O)c1ccc(-c2scc(Br)c2CC(=O)OC)cc1,,CN(C)C=O,,,,test
US20070088041A1,CN.COc1cc(-c2cc(-c3cc4ccccc4n3C(=O)OC(C)(C)C)c(OC)nn2)cc(C=O)c1OCOCC[Si](C)(C)C>>CNCc1cc(-c2cc(-c3cc4ccccc4n3C(=O)OC(C)(C)C)c(OC)nn2)cc(OC)c1OCOCC[Si](C)(C)C,,C1CCOC1,CO,CC(=O)O,[BH3-]C#N.[Na+],test
US20100256188A1,CC(=O)NC(C)c1ccc(Cl)c(N=C=S)c1.CNc1ccc(C(=O)Nc2ccc(Br)cc2)cc1N>>CNc1ccc(C(=O)Nc2ccc(Br)cc2)cc1NC(=S)Nc1cc(C(C)NC(C)=O)ccc1Cl,,CN(C)C=O,,,,test
US20160068529A1,CCOC(OCC)c1nn(C(=O)OC(C)(C)C)c2cnc(-c3cncc(CN(C)C)c3)cc12.Nc1cccc(N2CCCCC2)c1N>>CN(C)Cc1cncc(-c2cc3c(-c4nc5c(N6CCCCC6)cccc5[nH]4)n[nH]c3cn2)c1,,CN(C)C=O,,,,test
US20050009860A1,COC(=O)c1ccc(C(=O)OC)c(I)c1.Oc1ccccc1>>COC(=O)c1ccc(C(=O)OC)c(Oc2ccccc2)c1,,CCOC(C)=O,,Cc1ccccc1,O=C([O-])[O-].[Cs+].[Cs+],test
US20080070912A1,CC(C)c1nn2ccccc2c1C(NCc1ccccc1)C(C)C>>CC(C)c1nn2c(c1C(N)C(C)C)CCCC2,O=[Pt]=O,CC(=O)O,,,,test
US20070010511A1,CC=C[Mg]Br.COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OCc3ccccc3)CC2OCc2cccc([N+](=O)[O-])c2Br)cc1>>COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OCc3ccccc3)CC2OCc2ccc3c(C)c[nH]c3c2Br)cc1,,C1CCOC1,,[Cl-].[NH4+],,test
US20120010190A1,COC(=O)CC(=O)Nc1ccc(-c2ccc(C(C/C(=N\OC(=O)CC(=O)OC)c3ccc(=O)n(C)c3)c3ccc(F)cc3C)cc2)cc1>>Cc1cc(F)ccc1C(C/C(=N\O)c1ccc(=O)n(C)c1)c1ccc(-c2ccc(NC(=O)CC(=O)O)cc2)cc1,,C1COCCO1,O,[Li+].[OH-],,test
US20030166639A1,CC(C)c1ccc(-c2cccc(C(=O)CC(=O)Nc3cc(C(F)(F)F)ccc3NC(=O)OC(C)(C)C)c2)cn1>>CC(C)c1ccc(-c2cccc(C3=Nc4ccc(C(F)(F)F)cc4NC(=O)C3)c2)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120165322A1,CCOC(=O)c1cc2ccc(C#N)cc2[nH]1.CI>>CCOC(=O)c1cc2ccc(C#N)cc2n1C,,C1CCOC1,,[H-].[Na+],,test
US20080058327A1,COC(=O)C(CNC(=O)OC(C)(C)C)c1ccc(Cl)cc1.Cl>>COC(=O)C(CN)c1ccc(Cl)cc1.Cl,,C1COCCO1,CCOCC,,,test
US20110039840A1,BrCc1ccccc1.COC(=O)/C=C/c1ccc2c(c1)C(=O)NC1(CCN(C(=O)OC(C)(C)C)CC1)O2>>COC(=O)/C=C/c1ccc2c(c1)C(=O)N(Cc1ccccc1)C1(CCN(C(=O)OC(C)(C)C)CC1)O2,,CN(C)C=O,O,[H-].[Na+],[Cl-].[NH4+],test
US20130136782A1,BrCc1ccccc1.CCP(CC)CC>>CC[P+](CC)(CC)Cc1ccccc1.[Br-],,ClCCl,,,,test
US05096890,N#CC(c1ccccc1)(c1ccccc1)C1CCNC1.O>>NC(=O)C(c1ccccc1)(c1ccccc1)C1CCNC1,,O,O=S(=O)(O)O,[Na+].[OH-],,test
US20120329818A1,CN(C)C(=O)Oc1cccc(NC(=O)C2(C)CCNCC2)c1.Cc1c[nH]c2ncnc(Cl)c12>>Cc1c[nH]c2ncnc(N3CCC(C)(C(=O)Nc4cccc(OC(=O)N(C)C)c4)CC3)c12,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20080200444A1,CC(C)(C)OC(=O)N1CCCC(NC(=O)NC23CC4CC(CC(C4)C2)C3)C1.O=S(=O)(Cl)c1cccc(C(F)(F)F)c1>>O=C(NC1CCCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)C1)NC12CC3CC(CC(C3)C1)C2,,C1COCCO1,CO,CCN(CC)CC,Cl,test
US20050222118A1,CC(C)(C)OC(=O)N1CC(Cc2ccc(Cl)cc2)C1.O=C(O)C(F)(F)F>>Clc1ccc(CC2C[NH2+]C2)cc1.O=C([O-])C(F)(F)F,,ClCCl,,,,test
US20060004017A1,COc1cc2c(Oc3ccc4[nH]c(C)cc4c3)ncnc2cc1O.Cc1ccc(S(=O)(=O)C[C@H]2CCC(=O)N2)cc1>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3)ncnc2cc1OC[C@H]1CCC(=O)N1,,CN(C)C=O,,CCOCC,O=C([O-])[O-].[K+].[K+],test
US20060241115A1,CN(C)CCCN(C)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]>>CN(C)CCCN(C)c1ccc(C(F)(F)F)cc1N,[Pd],CO,,,,test
US20090023929A1,CN.C[O-].O=[N+]([O-])c1ccc(Cl)cc1Cl>>CNc1cc(OC)ccc1[N+](=O)[O-],,CC(=O)N(C)C,,O,,test
US06964981B2,C1CCOC1.O=C(OC1OCC(CN(Cc2ccccc2)Cc2ccccc2)C1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C=C(OC1OCC(CN(Cc2ccccc2)Cc2ccccc2)C1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,C1CCOC1,,CCOC(C)=O,O,test
US20110124679A1,COCOc1c(C)c(C)c2c(c1CCN)CCC(C)(C)O2.Cc1ccc(S(=O)(=O)Cl)cc1>>COCOc1c(C)c(C)c2c(c1CCNS(=O)(=O)c1ccc(C)cc1)CCC(C)(C)O2,,C1CCOC1,CCOC(C)=O,c1ccncc1,,test
US20150087600A1,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)N(c1cccc(F)c1)[C@H](C(=O)NC1CC(F)(F)C1)c1ccccc1Cl>>O=C(NC1CC(F)(F)C1)[C@H](c1ccccc1Cl)N(C(=O)[C@@H]1C[C@@H](O)CN1)c1cccc(F)c1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20070167443A1,COCCOc1ccc(I)cc1C.CON(C)C(=O)c1cn(Cc2cccc(Br)n2)c2ccccc2c1=O>>COCCOc1ccc(C(=O)c2cn(Cc3cccc(Br)n3)c3ccccc3c2=O)cc1C,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20020161000A1,COC(=O)c1cnc(O)c(C(=O)NCc2ccccc2)c1>>O=C(O)c1cnc(O)c(C(=O)NCc2ccccc2)c1,,CO,,[Na+].[OH-],,test
US05116842,CN(C)C(=O)Cl.O=C(Cc1ccc(Cl)c(Cl)c1)N1CCNCC1CN1CCCC1.c1ccncc1>>CN(C)C(=O)N1CCN(C(=O)Cc2ccc(Cl)c(Cl)c2)C(CN2CCCC2)C1.N,CN(C)c1ccncc1,ClCCl,,,,test
US20060183909A1,COC(=O)c1cc(O)c2cccc(OCc3ccccc3)c2n1.Cc1ccc(S(=O)(=O)N=C=O)cc1>>COC(=O)c1cc(NS(=O)(=O)c2ccc(C)cc2)c2cccc(OCc3ccccc3)c2n1,,ClCCCl,,,,test
US20120101134A1,CCOC(=O)CCc1cccc(-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)c1OC>>COc1c(CCC(=O)O)cccc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1,,CC(C)O,O,Cl,[Na+].[OH-],test
US20090156573A1,CC(C)(C)OC(=O)Nc1cnc(N2CCCC2)cc1C(F)(F)F.Cl>>Cl.Nc1cnc(N2CCCC2)cc1C(F)(F)F,,C1COCCO1,,CCOCC,,test
US20100278833A1,COC(=O)c1sc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)cc1OC(C)c1ccccc1OC(F)F.N>>CC(Oc1cc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)sc1C(N)=O)c1ccccc1OC(F)F,,CO,,,,test
US20030027302A1,COC(=O)CBr.COC(=O)[C@@H](N)Cc1ccc([N+](=O)[O-])cc1>>COC(=O)CN[C@@H](Cc1ccc([N+](=O)[O-])cc1)C(=O)OC,,C1CCOC1,,CCN(CC)CC,Cl,test
US05658854,COC(=O)c1cccc(N)c1SCc1ccccc1.O=CO>>COC(=O)c1cccc(NC=O)c1SCc1ccccc1,,C1CCOC1,,CC(=O)OC(C)=O,,test
US20090047246A1,CC1(C)OB(c2cc([N+](=O)[O-])cc([N+](=O)[O-])c2)OC1(C)C.CCOC(=O)Cc1cn(C(=O)OC(C)(C)C)c2cc(Br)ccc12>>CCOC(=O)Cc1cn(C(=O)OC(C)(C)C)c2cc(-c3cc([N+](=O)[O-])cc([N+](=O)[O-])c3)ccc12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20050137171A1,CO.CP(=O)(Oc1ccc([N+](=O)[O-])cc1)Oc1ccc([N+](=O)[O-])cc1.Oc1ccc2[nH]nc(-c3cc4ccccc4[nH]3)c2c1>>COP(C)(=O)Oc1ccc2[nH]nc(-c3cc4ccccc4[nH]3)c2c1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20040242588A1,Nc1ccc2nccnc2c1Br.S=C(Cl)Cl>>S=C=Nc1ccc2nccnc2c1Br,,O,,Br,,test
US04196208,CCCCCCCCCCCCCCCCNc1ccc(C(=O)OC(C)C(=O)Cl)cc1.CNC>>CCCCCCCCCCCCCCCCNc1ccc(C(=O)OC(C)C(=O)N(C)C)cc1,,c1ccncc1,,Cl,,test
US20070208007A1,Cc1cnc(C)c(C)c1.O=C(OO)c1cccc(Cl)c1>>Cc1cnc(C=O)c(C)c1,,ClCCl,,[Na+].[OH-],,test
US20050054819A1,CC(C)(C)OC(=O)N[C@H](CO)CCCCNC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N[C@H](C=O)CCCCNC(=O)OCc1ccccc1,,CS(C)=O,ClCCl,CCN(CC)CC,,test
US20130210796A1,CC(=O)OCc1nnnn1-c1ccc(C#N)c(C(F)(F)F)c1C>>Cc1c(-n2nnnc2CO)ccc(C#N)c1C(F)(F)F,,C1CCOC1,O,[Li+].[OH-],,test
US20140206650A1,COC(=O)[C@@H](C)OS(C)(=O)=O.Cn1c(=O)c2[nH]cnc2n(C)c1=O>>COC(=O)[C@H](C)n1cnc2c1c(=O)n(C)c(=O)n2C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100120844A1,CC(C)CC(O)Cc1cccc(F)c1>>CC(C)CC(=O)Cc1cccc(F)c1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20130046004A1,COc1cc(C(=O)O)nn1-c1ccccc1F.O=C(Cl)C(=O)Cl>>COc1cc(C(=O)Cl)nn1-c1ccccc1F,,CC1CCCO1,,CN(C)C=O,,test
US04833169,CC(=O)OC(C)=O.CCOC(=O)[C@@H]1CN(CC2=Cc3ccc(OC)cc32)CC[C@@H]1O.Cl>>CCOC(=O)[C@@H]1CN(CC2=Cc3ccc(OC)cc32)CC[C@@H]1OC(C)=O.Cl,,Cc1ccccc1,,[Na+].[OH-],,test
US20090023710A1,CC(=O)N1CCCCC1=O.NCc1ccccc1Oc1ccc(Cl)cc1>>CC(=O)N1CCC(NCc2ccccc2Oc2ccc(Cl)cc2)CC1,,ClCCCl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20080207590A1,CCOC(=O)/C=C/c1ccc(CN2C(=O)c3ccccc3Oc3ccccc32)cc1>>CCOC(=O)CCc1ccc(CN2C(=O)C3=C(C=CCC3)Oc3ccccc32)cc1,[Pd],CCO,,[H][H],,test
US03983135,CN1CC(=O)N=C1N.COc1ccc(N=C=O)cc1>>COc1ccc(NC(=O)N=C2NC(=O)CN2C)cc1,,CN(C)C=O,,,,test
US20080293776A1,O=C(Cl)c1ccccc1.O=C1CN(c2ccc(Cc3ccccc3)cc2O)S(=O)(=O)N1>>O=C1CN(c2ccc(Cc3ccccc3)cc2OC(=O)c2ccccc2)S(=O)(=O)N1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US05935993,CC(C)c1cc(C=O)cc(C(C)C)c1O.N#CCS(=O)(=O)CC#N>>CC(C)c1cc(/C=C(\C#N)S(=O)(=O)CC#N)cc(C(C)C)c1O,C1CCNCC1,CCO,,,,test
US05571775,Cn1ccc(N)n1.FC(F)(F)SCl>>Cn1cc(SC(F)(F)F)c(N)n1,,ClCCl,O,[Na+].[OH-],,test
US20130065881A1,CN1CCOc2c(NCCN3CCNCC3)nn3c(-c4cccc(OC(F)(F)F)c4)nnc3c21.CS(=O)(=O)Cl>>CN1CCOc2c(NCCN3CCN(S(C)(=O)=O)CC3)nn3c(-c4cccc(OC(F)(F)F)c4)nnc3c21,,CC#N,ClCCl,CCN(CC)CC,,test
US20100203647A1,C#CCCCCC(=O)NCCc1ccc(O)c(/N=N/c2ccc(C(=O)[O-])c(N3C(=O)CCC3=O)c2)c1.Nc1ccc(C(=O)O)cc1.O=N[O-]>>[N-]=[N+]=NCCc1ccc(O)c(/N=N/c2ccc(C(=O)O)cc2)c1,,C1CCOC1,Cl,O=C([O-])[O-].[K+].[K+],,test
US20130109661A1,C1CCNCC1.Nc1cccc(F)n1>>Nc1cccc(N2CCCCC2)n1,,O,,,,test
US20070054909A1,COc1cc(CC(=O)O)ccc1NC(=O)Nc1ccccc1C.Cc1c(C(=O)O)ccc(OCCN)c1[N+](=O)[O-]>>COc1cc(CC(=O)NCCOc2ccc(C(=O)O)cc2[N+](=O)[O-])ccc1NC(=O)Nc1ccccc1C,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20090163586A1,COc1ccc(NS(=O)(=O)CCc2ccc(Cl)cc2)c(S(N)(=O)=O)c1>>NS(=O)(=O)c1cc(O)ccc1NS(=O)(=O)CCc1ccc(Cl)cc1,,ClCCl,,BrB(Br)Br,,test
US20020086891A1,CN(C)CC#Cc1ccc2c(-c3ccc(Cl)cc3)nsc2c1>>CN(C)CCCc1ccc2c(-c3ccc(Cl)cc3)nsc2c1,O=[Pt]=O,CCO,,,,test
US20040087577A1,CC(C)[Si](Oc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3sccc3n(Cc3cnc(Cl)s3)c1=O)N2)(C(C)C)C(C)C>>O=c1c(C2=NS(=O)(=O)c3cc(O)ccc3N2)c(O)c2sccc2n1Cc1cnc(Cl)s1,,C1CCOC1,O,Cl,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20030207305A1,CSc1nc2ccccc2s1.O=[N+]([O-])O>>CSc1nc2ccc([N+](=O)[O-])cc2s1,,O=S(=O)(O)O,,,,test
US05688803,CCOC(=O)c1c(O)c2ccc([N+](=O)[O-])cc2[nH]c1=O.C[Si](C)(C)NO>>O=C(NO)c1c(O)c2ccc([N+](=O)[O-])cc2[nH]c1=O,,C1COCCO1,,,,test
US20050192359A1,CCOC(=O)C(=O)c1ccc(C)cc1>>Cc1ccc(C(=O)C(=O)O)cc1,,CCO,,Cl,[Na+].[OH-],test
US20110275797A1,C1CCNCC1.COCOc1ccc(CBr)cc1C(=O)Nc1cc(-c2ccccc2)ccc1C(=O)OC(C)(C)C>>COCOc1ccc(CN2CCCCC2)cc1C(=O)Nc1cc(-c2ccccc2)ccc1C(=O)OC(C)(C)C,,CC(C)=O,,,,test
US20130053397A1,COC(=O)c1cc(OC)cc2c1ccn2C(C)C>>COC(=O)c1cc(O)cc2c1ccn2C(C)C,,Cc1ccccc1,O,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20070149574A1,CC(=O)Nc1cc(COS(C)(=O)=O)ccn1.Cc1cc(C)cc(NC(=O)c2ccc[nH]c2=S)c1>>CC(=O)Nc1cc(CSc2ncccc2C(=O)Nc2cc(C)cc(C)c2)ccn1,,CN(C)C=O,,CCN(CC)CC,CCOC(C)=O,test
US20130224186A1,C[C@H](O)C(=O)N(C[C@@H]1CN(C(=O)OCc2ccccc2)C[C@@H]1F)[C@@H](c1nc(-c2cc(F)ccc2F)oc1Cc1ccccc1)C(C)(C)C>>C[C@H](O)C(=O)N(C[C@@H]1CNC[C@@H]1F)[C@@H](c1nc(-c2cc(F)ccc2F)oc1Cc1ccccc1)C(C)(C)C,[Pd],CCO,,,,test
US04931455,CC(=O)Cl.CCc1cc(NC(CC)CCCCCCN)nc(Cl)n1.COc1cc(CNCCCNCCCCNCCCN)ccc1O>>CCc1cc(NC(CC)CCCCCCNC(C)=O)nc(Cl)n1.COc1cc(CNCCCNCCCCNCCCN)ccc1O,,ClC(Cl)Cl,,CCN(CC)CC,,test
US05753664,CC(=O)Oc1ccc(C(=O)c2ccc(CSc3nc4scc(C)c4c(=O)n3C)cc2)cc1>>Cc1csc2nc(SCc3ccc(C(=O)c4ccc(O)cc4)cc3)n(C)c(=O)c12,,C1CCOC1,,O,[Na+].[OH-],test
US20150023916A1,CCOc1ccc(N)cc1.O=[N+]([O-])c1cc(Br)ccc1F>>CCOc1ccc(Nc2ccc(Br)cc2[N+](=O)[O-])cc1,,CC#N,,CCN(CC)CC,,test
US20090163472A1,C=O.O=[N+]([O-])c1cc(Br)ccc1NC1CNC1>>CN1CC(Nc2ccc(Br)cc2[N+](=O)[O-])C1,,CC#N,CCOC(C)=O,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20150210657A1,COc1ccc2nc(C)cnc2c1>>COc1ccc2c(c1)NC[C@H](C)N2,,Cc1ccccc1,,,,test
US20120071503A1,O=C1c2ccc(O)cc2C(=O)N1C1CCCC1>>O=C1c2ccc(O)cc2CN1C1CCCC1,[Zn],CC(=O)O,,,,test
US05073558,CCOCCc1ccc(OCCN(C(=O)Cl)c2ncnc(C)c2Cl)c(C)c1.CN>>CCOCCc1ccc(OCCN(C(=O)NC)c2ncnc(C)c2Cl)c(C)c1,,Cc1ccccc1,,,,test
US20020103199A1,Nc1nc2ccc(F)cc2s1.O=C(O)C(CC1CCCC1)c1ccc(Cl)c(Cl)c1>>O=C(Nc1nc2ccc(F)cc2s1)C(CC1CCCC1)c1ccc(Cl)c(Cl)c1,CN(C)C=O,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20060178362A1,NN1CCCc2ccccc21.O=C1CCCNCC1>>c1cc2c3c(c1)c1c(n3CCC2)CCNCC1,,CCO,,Cl,Cl,test
US20060173184A1,COc1cc(Br)cc(CN2CCN(C(=O)Nc3ccccc3)CC2)c1O.Cl>>COc1cc(Br)cc(CN2CCN(C(=O)Nc3ccccc3)CC2)c1O.Cl,,CCOCC,,,,test
US20040127574A1,CCOC(=O)C(Cc1cccc(C(F)(F)F)c1)C(O)c1ccc(F)cc1>>O=C(O)C(Cc1cccc(C(F)(F)F)c1)C(O)c1ccc(F)cc1,,CO,,Cl,[Na+].[OH-],test
US20020004522A1,COc1ccc(C=O)cc1F.Fc1cccc(Br)c1>>COc1ccc(C(O)c2cccc(F)c2)cc1F,,C1CCOC1,,,,test
US20160264518A1,COC(=O)/C=C/c1ccccc1N.Clc1cc(CBr)c(CBr)cc1Cl>>COC(=O)/C=C/c1ccccc1N1Cc2cc(Cl)c(Cl)cc2C1,,CN(C)C=O,O,[K],,test
US20070238733A1,NS(=O)(=O)c1cccc(NC(=O)c2ccccc2Br)c1.Oc1ccccc1N1CCCCC1>>NS(=O)(=O)c1cccc(NC(=O)c2ccccc2Oc2ccccc2N2CCCCC2)c1,[Cu]I,CN(C)C=O,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US04021432,CC1(C)CC(OCc2ccccc2)CC(C)(C)N1.CCOC(=O)CBr>>CCOC(=O)CN1C(C)(C)CC(OCc2ccccc2)CC1(C)C,,CCO,,,,test
US20100204214A1,NCCO.O=[N+]([O-])c1cc(Br)ccc1F>>O=[N+]([O-])c1cc(Br)ccc1NCCO,,CCCCO,,,,test
US20080194561A1,CN(C)CCCN.O=[N+]([O-])c1cccc(S(=O)(=O)Cl)c1>>CN(C)CCCNS(=O)(=O)c1cccc([N+](=O)[O-])c1,,C1CCOC1,,CCN(CC)CC,O,test
US05658923,CCCCCCCC.CCN(CC)CC.CCN=C=NCCCN(C)C.ClCCl.O=C(O)Cc1ccccn1>>CC1(C)C2CC[C@]1(C)CN(C(=O)Cc1ccccn1)C2,,ClCCl,,Cl,Cl,test
US20100261710A1,CC(C)(C)OC(=O)C1Cn2ccc3c(C(=O)NCc4ccc(C(=O)NOC5CCCCO5)cc4)ccc(c32)CN1>>CC(C)(C)OC(=O)C1Cn2ccc3c(C(=O)NCc4ccc(C(=O)NO)cc4)ccc(c32)CN1,,C1CCOC1,,CC(=O)O,O,test
US20100004238A1,O=C1NCc2ccc(Oc3ccc([N+](=O)[O-])cc3Cl)cc21>>Nc1ccc(Oc2ccc3c(c2)C(=O)NC3)c(Cl)c1,[Pt],C1CCOC1,,CO,,test
US20100197665A1,CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(S(=O)(=O)c5cc(F)cc(F)c5)cc34)c(N(C(=O)C(F)(F)F)C3CCOCC3)c2)CC1>>CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(S(=O)(=O)c5cc(F)cc(F)c5)cc34)c(NC3CCOCC3)c2)CC1,,CO,,CCN(CC)CC,,test
US06759414B2,O=C(Nc1ccc(Cl)cn1)c1ccccc1NCC1CCNCC1.O=C(O)c1cnccc1Cl>>O=C(O)c1cnccc1C1(C(=O)Nc2ccc(Cl)cn2)C=CC=CC1NCC1CCNCC1,,CCO,,CCN(CC)CC,,test
US20050070559A1,CCCc1ccc2c(c1)N(OC)C(=O)C2>>CCCc1ccc2c(c1)NC(=O)C2,[Pd],CO,,,,test
US04049417,NCCCN(CC(O)CO)CC(O)CO.OCC1CO1>>OCC(O)CNCCCN(CC(O)CO)CC(O)CO,,CO,,,,test
US20100021423A1,COc1c(CC(C)(C=O)c2ccc(NS(C)(=O)=O)cc2)cc(Br)cc1C(C)(C)C>>COc1c(CC(C)(CO)c2ccc(NS(C)(=O)=O)cc2)cc(Br)cc1C(C)(C)C,,CO,,[BH4-].[Na+],,test
US04631285,CCOCc1cccc2[nH]cc(C(COC)C(C(=O)OCC)[N+](=O)[O-])c12>>CCOCc1cccc2[nH]cc(C(COC)C(N)C(=O)OCC)c12,[Ni],CCO,,,,test
US20130324737A1,O=C1CCC(=O)N1Cl.c1cncc(-c2ncc(NC3CC3)s2)c1>>Clc1nc(-c2cccnc2)sc1NC1CC1,,CC#N,,,,test
US20110130380A1,COC[C@H]1C[C@@H](O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)CN1C(=O)OC(C)(C)C>>COC[C@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140038921A1,CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O>>CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@H]1C/C=C\CCCC(=O)O,,CCO,,,,test
US20130158067A1,BrBr.O=C1CCc2cccc(F)c21>>O=C1CCc2c(Br)ccc(F)c21,,CC(Cl)Cl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20150119362A1,CCOC(=O)Cc1ccc(Nc2cc(SC3CCCC3)nc3c2CCC3)cc1.N>>NC(=O)Cc1ccc(Nc2cc(SC3CCCC3)nc3c2CCC3)cc1,,CO,,,,test
US06242598B1,Cc1ccc(-c2nc(Oc3ccccc3)nc(-c3ccc(C)cc3C)n2)c(C)c1.Oc1cccc(O)c1>>Cc1ccc(-c2nc(-c3ccc(C)cc3C)nc(-c3ccc(O)cc3O)n2)c(C)c1,,CCOC(C)=O,,,,test
US20020010183A1,CCCC[Sn](CCCC)(CCCC)c1ccncc1.O=c1c2c([nH]c3ccccc13)C(c1ccc3c(c1)OCO3)N(c1ncc(Br)cn1)C2>>O=c1c2c([nH]c3ccccc13)C(c1ccc3c(c1)OCO3)N(c1ncc(-c3ccncc3)cn1)C2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,CN(C)C=O,,,test
US20100041637A1,CC(C)(C)[S@](N)=O.C[C@@H](c1ccc(Br)cc1)N(CCCC(=O)c1ccccc1)C(=O)OC(C)(C)C>>C[C@@H](c1ccc(Br)cc1)N(CCC/C(=N\[S@](=O)C(C)(C)C)c1ccccc1)C(=O)OC(C)(C)C,,C1CCOC1,,,,test
US08017608B2,CC[N+](=O)[O-].CS(=O)(=O)c1ccc(C=O)cc1C(F)(F)F>>CC(=Cc1ccc(S(C)(=O)=O)c(C(F)(F)F)c1)[N+](=O)[O-],,ClCCl,,C,O=C[O-].[NH4+],test
US04683239,CC(=O)c1ccc(OCc2ccccc2)cc1.O=Cc1ccccn1>>O=C(C=Cc1ccccn1)c1ccc(OCc2ccccc2)cc1,,CN(C)C=O,,O,[Na+].[OH-],test
US20120053053A1,C=C(OCC)c1c(N)nc(-c2ccc(C(F)(F)F)cc2)nc1C(=O)OC>>COC(=O)c1nc(-c2ccc(C(F)(F)F)cc2)nc(N)c1C(C)=O,,C1CCOC1,,Cl,,test
US20030105123A1,COc1ccc(C=O)cc1OC.C[N+](=O)[O-]>>C=Cc1ccc(OC)c(OC)c1[N+](=O)[O-],,CC(=O)O,,C,O=C[O-].[NH4+],test
US20150320702A1,NC1CCCC1.O=C1C=C(Br)C(=O)c2ccccc21>>O=C1C=C(NC2CCCC2)C(=O)c2ccccc21,,CCO,,,,test
US20130237573A1,CC(C)(C)OC(=O)N[C@@]1(C(=O)OC(C)(C)C)[C@H](OCc2ccc(Cl)c(Cl)c2)[C@@H](Sc2nc[nH]n2)[C@H]2[C@H](C(=O)OC(C)(C)C)[C@H]21.CI>>Cn1cnc(S[C@H]2[C@H]3[C@H](C(=O)OC(C)(C)C)[C@H]3[C@](NC(=O)OC(C)(C)C)(C(=O)OC(C)(C)C)[C@@H]2OCc2ccc(Cl)c(Cl)c2)n1,,C1CCOC1,O,Cl,CC(C)(C)[O-].[K+],test
US05250522,COC(=O)[C@@H](N)C(Cc1ccc(-c2ccccc2)cc1)C(=O)OC(C)(C)C.COP(=O)(COS(=O)(=O)C(F)(F)F)OC>>COC(=O)C[C@H](Cc1ccc(-c2ccccc2)cc1)NCP(=O)(OC)OC,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20090088425A1,COC(=O)COc1cc(C(O)(C(C)c2ccc(Cl)cc2Cl)C(F)(F)F)ccn1>>CC(c1ccc(Cl)cc1Cl)C(O)(c1ccnc(OCCO)c1)C(F)(F)F,Cl,C1CCOC1,,O,[BH4-].[Li+],test
US20070010511A1,CC(C)[Si](OCCI)(C(C)C)C(C)C.COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2OCc2ccc(Br)c(NC(=O)C(C)C)c2)cc1>>COc1ccccc1COCCCOc1ccc(C2CCN(C(=O)OC(C)(C)C)CC2OCc2ccc(Br)c(N(CCO[Si](C(C)C)(C(C)C)C(C)C)C(=O)C(C)C)c2)cc1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20100075948A1,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2)C1(C#N)c1ccc(Cl)cc1.OCCN1CCNCC1>>CC(C)(C)CC1NC(C(=O)N2CCN(CCO)CC2)C(c2cccc(Cl)c2)C1(C#N)c1ccc(Cl)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150210688A1,COC(=O)c1ccc(Cl)c(-c2[nH]c(C)nc2C)c1>>Cc1nc(C)c(-c2cc(C(=O)O)ccc2Cl)[nH]1,,CO,,[Na+].[OH-],,test
US20120083475A1,CC1(C)OC(=O)C2(CC2)C(=O)O1.Nc1ccccc1Cl>>O=C(O)C1CCN(c2ccccc2Cl)C1=O,,CCO,,,,test
US20020169188A1,CCOC(CSc1ccc(Br)cc1)OCC>>Brc1ccc2sccc2c1,,Clc1ccccc1,,O=P(O)(O)O,,test
US06194410B1,COc1ccc(S(=O)(=O)c2c(SC)nn3c(Cl)cc(C)nc23)cc1.N>>COc1ccc(S(=O)(=O)c2c(SC)nn3c(N)cc(C)nc23)cc1,,CO,,,,test
US20100137299A1,O=C1C(=O)N(Cc2ccc(Cl)s2)c2ccccc21.Oc1ccc(OCc2ccccc2)cc1>>O=C1N(Cc2ccc(Cl)s2)c2ccccc2C1(O)c1cc(OCc2ccccc2)ccc1O,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20040097555A1,COc1ccc(C(=O)C(Br)c2cccnc2)cc1.NC(N)=S>>COc1ccc(-c2nc(N)sc2-c2cccnc2)cc1,,CC#N,,Br,CCN(CC)CC,test
US20100331326A1,Brc1csc2ccccc12.Cc1ccncc1N1CCNC1=O>>Cc1ccncc1N1CCN(c2csc3ccccc23)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20040058903A1,CC(C)(C)OC(=O)Nc1cccc(C(=O)NCc2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2)n1>>NC(=O)c1ccccn1,,CO,,C1COCCO1,Cl,test
US20110118236A1,CC(C)=O.COc1ccc(Cl)cc1NC(=O)Cn1nc(C(F)(F)F)c2c1CCNC2>>COc1ccc(Cl)cc1NC(=O)Cn1nc(C(F)(F)F)c2c1CCN(C(C)C)C2,,CO,,[BH3-]C#N.[Na+],,test
US20100179137A1,CCc1cccc(OCc2c(Cl)cc(Cl)c(=O)n2CCc2ccc(C(=O)n3ccnc3)cc2)c1.CS(N)(=O)=O>>CCc1cccc(OCc2c(Cl)cc(Cl)c(=O)n2CCc2ccc(C(=O)NS(C)(=O)=O)cc2)c1,,C1COCCO1,ClC(Cl)Cl,C1CCC2=NCCCN2CC1,Cl,test
US20150031685A1,COC(=O)Cc1cccc(N)c1.O=C(Cl)C=Cc1ccccc1>>COC(=O)Cc1cccc(NC(=O)/C=C/c2ccccc2)c1,,ClCCl,c1ccncc1,,,test
US20140357618A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.OC1CC=CC1>>CC(C)(C)[Si](OC1CC=CC1)(c1ccccc1)c1ccccc1,,ClCCl,O,c1c[nH]cn1,,test
US04772596,BrC(c1ccccc1)c1ccccc1.OC1CCCNC1>>OC1CCCN(C(c2ccccc2)c2ccccc2)C1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070191289A1,CC(C)(C)C(=O)OC[C@H]1O[C@@H](Oc2nn(CCCOS(C)(=O)=O)c3nccc(CCc4ccc(OC(=O)C(C)(C)C)cc4)c23)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C.[N-]=[N+]=[N-]>>CC(C)(C)C(=O)OC[C@H]1O[C@@H](Oc2nn(CCCN=[N+]=[N-])c3nccc(CCc4ccc(OC(=O)C(C)(C)C)cc4)c23)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C,,CN(C)C=O,,O,,test
US20070225267A1,C=CC(C)(C)C.O=C(Cl)C(Cl)(Cl)Cl>>CC(C)(C)C1CC(=O)C1(Cl)Cl,[Zn],CCOCC,,COCCOC,,test
US20120214837A1,CC(=O)NCCN.COc1ccc2nc(Cl)c(C=O)cc2c1>>COc1ccc2nc(NCCNC(C)=O)c(C=O)cc2c1,,C1CCOC1,,,,test
US20110236952A1,C(=NC1CCCCC1)=NC1CCCCC1.O=C(O)c1ccccc1CNC(=O)C(F)(F)F>>O=C(NC1CCCCC1)NC1CCCCC1,,C1CCOC1,,,,test
US20130109679A1,CI.O=[N+]([O-])c1ncc[nH]1>>Cn1ccnc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150336962A1,CC(C)(C)OC(=O)Nc1nn2cccnc2c1C(=O)O.Nc1cn[nH]c1-c1cc(Cl)ccc1OC(F)F>>CC(C)(C)OC(=O)Nc1nn2cccnc2c1C(=O)Nc1c[nH]nc1-c1cc(Cl)ccc1OC(F)F,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05393875,CC(C)(C(=O)Cl)S(=O)(=O)CC(Cc1ccccc1)C(=O)OCc1ccccc1.CC1CNCC(C)O1>>C[C@H]1CN(C(=O)C(C)(C)S(=O)(=O)CC(Cc2ccccc2)C(=O)OCc2ccccc2)C[C@@H](C)O1,,c1ccncc1,,,,test
US20100204218A1,C=C[Sn](CCCC)(CCCC)CCCC.CC1(C)Oc2cc(Cl)ccc2C(c2ccc(F)cc2)=C1Br>>C=CC1=C(c2ccc(F)cc2)c2ccc(Cl)cc2OC1(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,[F-].[K+],,test
US07662956B2,CCOC(=O)C1CCN(C(=O)CN2CC(c3cccc(OC)c3OC)c3cc(Cl)ccc3C(CC(C)C)C2=O)CC1>>COc1cccc(C2CN(CC(=O)N3CCC(C(=O)O)CC3)C(=O)C(CC(C)C)c3ccc(Cl)cc32)c1OC,,C1COCCO1,O,Cl,[Na+].[OH-],test
US20100240702A1,COCC(=O)C(C)(C)C(=O)OC.Nc1ccccc1N>>COCC(Nc1ccccc1N)C(C)(C)C(=O)OC,,CCOC(C)=O,CO,CC(=O)O,[BH3-]C#N.[Na+],test
US20020035094A1,CI.O=[N+]([O-])c1ccc(NC2CCCCC2)nc1>>CN(c1ccc([N+](=O)[O-])cn1)C1CCCCC1,,CN(C)C=O,,[H-].[Na+],,test
US20110313002A1,COc1ccc(OC)c2c1CC1=C(O2)C(=O)N([C@@H](CC2CCCCC2)C(=O)O)C1.Nc1ccccn1>>COc1ccc(OC)c2c1CC1=C(O2)C(=O)N([C@@H](CC2CCCCC2)C(=O)Nc2ccccn2)C1,,C1CCOC1,O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05726182,O=C(NC1CCN(Cc2ccccc2)C1)C(F)(F)F>>FC(F)(F)CNC1CCN(Cc2ccccc2)C1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100160317A1,CCOC(=O)c1c(C)c[nH]c1CC(=O)NC[C@H](O)CN1CCOCC1>>CCOC(=O)c1c(C)c[nH]c1CCNC[C@H](O)CN1CCOCC1,,C1CCOC1,,,,test
US20140275071A1,C[Si](C)(C)CCOCCl.Cn1c(=O)[nH]c(=O)c2c1nc(Br)n2Cc1ccc(Cl)cc1>>Cn1c(=O)[nH]c(=O)c2c1nc(Br)n2COCC[Si](C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04281178,O=C(O)c1ccccc1.O=C(OCc1ccccc1)c1ccccc1>>O=C(O)c1ccccc1.O=Cc1ccccc1,,Cc1ccccc1,,O=O,,test
US20140155413A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Clc1nccc2c(I)c[nH]c12>>CC(C)(C)OC(=O)n1cc(I)c2ccnc(Cl)c21,,C1CCOC1,,CCOC(C)=O,[H-].[Na+],test
US04871748,COCC(C)(C)c1ccncc1>>COCC(C)(C)C1CCNCC1,O=[Pt]=O,CC(=O)O,,,,test
US20130012513A1,CC(=O)c1ccc([N+](=O)[O-])cc1Cl.O=C1CCC(=O)N1Br>>O=C(CBr)c1ccc([N+](=O)[O-])cc1Cl,,CC#N,,,,test
US20060019997A1,CC(Cl)c1nc(=O)n(-c2cccc(Cl)c2)[nH]1.CNc1nnc(-c2ccncc2)n1C>>CC(c1nn(-c2cccc(Cl)c2)c(=O)[nH]1)N(C)c1nnc(-c2ccncc2)n1C,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US04705797,C=CC(C)=O.CNCCC(c1ccccc1)c1ccccc1>>CC(=O)CCN(C)CCC(c1ccccc1)c1ccccc1,,CCOCC,,,,test
US20080009541A1,CC(C)(C)OC(=O)NCc1cccc(C(F)(F)F)c1C#N.O=C(O)C(F)(F)F>>N#Cc1c(CN)cccc1C(F)(F)F.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20150110809A1,Cc1ccc(C)c(CSc2nc(C3CCN(C(=O)OC(C)(C)C)CC3)c(C#N)c(=O)[nH]2)c1>>Cc1ccc(C)c(CSc2nc(C3CCNCC3)c(C#N)c(=O)[nH]2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120010183A1,CC(C)(C)OC(=O)c1cc(Cl)c(Oc2cnc(C3CC3)c(Cl)c2)cc1F>>O=C(O)c1cc(Cl)c(Oc2cnc(C3CC3)c(Cl)c2)cc1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US05750702,CCOc1ccc(NC(=O)c2c([N+](=O)[O-])[nH]c3c2C(=O)CCC3)cc1>>CCOc1ccc(NC(=O)c2c(N)[nH]c3c2C(=O)CCC3)cc1,[Pd],CCO,,,,test
US04511392,CCOC(=O)Cl.NC(=NO)c1ccccc1[N+](=O)[O-]>>O=c1[nH]c(-c2ccccc2[N+](=O)[O-])no1,,c1ccncc1,,,,test
US20110288066A1,CCOC(=O)C(C(=O)OCC)c1ncc(S(=O)(=O)N(C)C)cc1Br>>Cc1ncc(S(=O)(=O)N(C)C)cc1Br,,O,,Cl,,test
US20080020986A1,CC1CCN(C(=O)OC(C)(C)C)C1Cc1c[nH]c2cc(F)ccc12>>CC1CCNC1Cc1c[nH]c2cc(F)ccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060166894A1,CO.N[C@@H](CCC(=O)O)C(=O)O>>COC(=O)CC[C@H](N)C(=O)O,,c1ccncc1,,CC(=O)Cl,,test
US20100004233A1,C=O.Cc1c(Cc2cccc([N+](=O)[O-])c2)c(=O)oc2cc(OC(=O)N(C)C)c(Cl)cc12>>CN(C)C(=O)Oc1cc2oc(=O)c(Cc3cccc([N+](=O)[O-])c3)c(CCO)c2cc1Cl,,C1CCOC1,,O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US04097477,CC(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CC[C@H](C(=O)CO)[C@@]4(C)CC[C@@H]32)C1.COC(=O)CC(=O)OC>>COC(=O)CC(=O)OCC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(C)=O)CC[C@]4(C)[C@H]3CC[C@]12C,,Cc1ccccc1,,[Ca+2].[Cl-].[Cl-],,test
US04705786,CC(=O)Cc1nc(CCl)no1.CC(N)=Cc1nc(CCl)ns1.O=Cc1cccc([N+](=O)[O-])c1>>CC1=C(c2nc(CCl)no2)C(c2cccc([N+](=O)[O-])c2)C(c2nc(CCl)ns2)=C(C)N1,,CC(C)O,,,,test
US20150368269A1,CC(C)(C)OC(=O)Nc1cc2onc(N3C(=O)c4ccccc4C3=O)c2cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1cc2onc(N3C(=O)c4ccccc4C3=O)c2cc1N,,CCOC(C)=O,O,CN(C)C=O,,test
US20070259877A1,COc1ccc(N2C[C@H](C)N[C@H](C)C2)cc1N.O=S(=O)(Cl)c1ccc(-c2cccs2)cc1>>COc1ccc(N2C[C@H](C)N[C@H](C)C2)cc1NS(=O)(=O)c1ccc(-c2cccs2)cc1,,c1ccncc1,,,,test
US20160009703A1,FC(F)(F)c1cccc(C2CCNCC2)c1.Fc1ccc2nnn(CCCCCl)c2c1>>FC(F)(F)c1cccc(C2CCN(CCCCn3nnc4ccccc43)CC2)c1,,CC#N,,CCN(C(C)C)C(C)C,[I-].[K+],test
US20160200725A1,COC(=O)COC1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(OCCO)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06329370B1,COc1ccc2c(Cc3c(Cl)cncc3Cl)nnc(Cl)c2c1.Oc1ccccc1>>COc1ccc2c(Cc3c(Cl)cncc3Cl)nnc(Oc3ccccc3)c2c1,,CN(C)C=O,,[H-].[Na+],,test
US20150344466A1,CCOC(=O)c1cc(Cc2ccccc2C)on1>>Cc1ccccc1Cc1cc(C(=O)O)no1,,O,,CCO,[Na+].[OH-],test
US20140315894A1,CCOC(=O)CC(=O)c1ccc(OC)c(OC)c1.CNN>>COc1ccc(C2=NN(C)C(=O)C2)cc1OC,,CCO,,,,test
US06855711B1,Oc1ccc(CCl)c2cccnc12.c1c[nH]cn1>>Oc1ccc(Cn2ccnc2)c2cccnc12,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,Cl,test
US20090029939A1,CCOC(=O)c1ccccc1-c1c2c(c(OC(c3ccccc3)c3ccccc3)c3ncccc13)C(=O)N(Cc1ccc(F)cc1)C2>>CCOC(=O)c1ccccc1-c1c2c(c(O)c3ncccc13)C(=O)N(Cc1ccc(F)cc1)C2,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20050107364A1,C=CCC(C)(C(=O)OCc1ccccc1)c1ccccc1>>CCCC(C)(C(=O)O)c1ccccc1,[Pd],CCOC(C)=O,,,,test
US20040116424A1,CCCCOC(=O)c1nnc(-c2ccccc2)n1CCCC>>CCCCn1c(CO)nnc1-c1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20020068756A1,CC(C)=O.O=CN(c1cccnc1)c1c(OCc2ccccc2)c2cc(Br)ccc2n1Cc1ccc(F)cc1>>CC(C)(O)c1ccc2c(c1)c(OCc1ccccc1)c(N(C=O)c1cccnc1)n2Cc1ccc(F)cc1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20070213335A1,CC(C)(C)CCN.CCOC(=O)c1c(Cl)cc(C)nc1Cl>>CCOC(=O)c1c(NCCC(C)(C)C)cc(C)nc1Cl,,CCO,CCOC(C)=O,,,test
US20090105219A1,COC(=O)Cn1c(=O)n(CC(=O)OC)c2c([N+](=O)[O-])c(Cl)nc(Cl)c21>>COC(=O)Cn1c(=O)n2c3c(cncc31)NC(=O)C2,[Pd],CO,,,,test
US05153318,CCNC.Nc1nc(Cl)c2[nH]cnc2n1>>CCc1nc(N)nc2c1ncn2NC,,O,,CC#N,,test
US20080096874A1,CCOC(=O)C(C(=O)OCC)c1ccc(C2CCC3(CC2)OCCO3)cc1>>CCOC(=O)C(C(=O)OCC)c1ccc(C2CCC(=O)CC2)cc1,,C1CCOC1,,Cl,,test
US20160083363A1,CCOC(=O)c1[nH]c2ccc(C(F)(F)F)cc2c1-c1ccc(OC)nc1.COc1cccc(CBr)c1>>CCOC(=O)c1c(-c2ccc(OC)nc2)c2cc(C(F)(F)F)ccc2n1Cc1cccc(OC)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110218221A1,CCN(CC)CCSc1ccc(/C=C/C(=O)OC)cc1N.O=CCCc1ccccc1>>CCN(CC)CCSc1ccc(/C=C/C(=O)OC)cc1NCCCc1ccccc1,,CC#N,CCOC(C)=O,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130040962A1,CC(C)(C)c1cc(N)n(-c2ccc(C(=O)O)c(Cl)c2)n1>>CC(C)(C)c1cc(N)n(-c2ccc(CO)c(Cl)c2)n1,,C1CCOC1,,B,,test
US20120040968A1,CS(=O)(=O)c1cccc(Nc2nc(N[C@@H]3CC[C@@H](O)CC3)c(Br)nc2C(N)=O)c1.OB(O)C1CC1>>CS(=O)(=O)c1cccc(Nc2nc(N[C@@H]3CC[C@@H](O)CC3)c(C3CC3)nc2C(N)=O)c1,,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(Cl)nc1-c1ccc(C)cc1.OB(O)c1ccccc1>>CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1-c1ccc(C)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,CCN(C(C)C)C(C)C,,test
US20090192138A1,C[Si](C)(C)CCOCCl.Cn1c(=O)[nH]c(=O)c2c1c(C#N)c(N1CCCN(C(=O)OC(C)(C)C)CC1)n2Cc1ccccc1>>Cn1c(=O)n(COCC[Si](C)(C)C)c(=O)c2c1c(C#N)c(N1CCCN(C(=O)OC(C)(C)C)CC1)n2Cc1ccccc1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20150119373A1,CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC[C@@H]2[C@H]4[C@H](C5(C)CC5)CC[C@]4(C(=O)N4CCOCC4)CC[C@]23C)C1(C)C>>CC1([C@@H]2CC[C@]3(C(=O)N4CCOCC4)CC[C@]4(C)[C@H](CC[C@@H]5[C@@]6(C)CC[C@H](O)C(C)(C)[C@@H]6CC[C@]54C)[C@@H]23)CC1,,C1CCOC1,CO,O=C([O-])[O-].[K+].[K+],,test
US20100137313A1,CNC.CNc1ncc(Br)cc1C(=O)OC>>COC(=O)c1cc(Br)cnc1N(C)C,,C1CCOC1,,,,test
US20160194304A1,CN(C(=O)c1cc(-c2cc3c(cc2C(=O)N2Cc4ccccc4C[C@H]2CN2CCOCC2)CN(C(=O)NC(C)(C)C)C3)n2c1CCCC2)c1ccc(O)cc1.Cl>>CN(C(=O)c1cc(-c2cc3c(cc2C(=O)N2Cc4ccccc4C[C@H]2CN2CCOCC2)CN(C(=O)NC(C)(C)C)C3)n2c1CCCC2)c1ccc(O)cc1.Cl,,CC(C)O,,,,test
US20020006956A1,COc1cccc2c1CCCC(=O)C2.NCc1ccccc1>>COc1cccc2c1CCCC(NCc1ccccc1)C2,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20110104765A1,COc1ccc(CC(C)(N)C(=O)OC(C)(C)C)cc1>>C[C@](N)(Cc1ccc(O)cc1)C(=O)O,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20150119435A1,CS(=O)(=O)Cl.OCCOCCOCCC12CC3CC(CC(C3)C1)C2>>CS(=O)(=O)OCCOCCOCCC12CC3CC(CC(C3)C1)C2,,Cl,,CCN(CC)CC,CCOC(C)=O,test
US20150344468A1,COCn1c(=O)sc2cc(C(C)c3nc(-c4ccc(C#CC(C)(C)OC5CCCCO5)cn4)cs3)ccc21>>COCn1c(=O)sc2cc(C(C)c3nc(-c4ccc(CCC(C)(C)OC5CCCCO5)cn4)cs3)ccc21,[Pd],CO,,,,test
US20110053940A1,CCOC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@H]1c1cc(=O)n(C)c(C)c1C>>Cc1c([C@@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2C(=O)O)cc(=O)n(C)c1C,,CO,,C1CCOC1,[Li+].[OH-],test
US20040209892A1,CS(=O)(=O)c1nccc(Oc2ccc([N+](=O)[O-])c([N+](=O)[O-])c2)n1>>CS(=O)(=O)c1nccc(Oc2ccc(N)c(N)c2)n1,[Pd],CO,,,,test
US08188082B2,CC(C)c1nc(I)cn1CCNC(=O)OC(C)(C)C.Cl>>CC(C)c1nc(I)cn1CCN.Cl,,ClCCl,,C1COCCO1,,test
US06218376B1,COc1ccc(Cn2c(C)nc3c(=O)c4ccccc4ccc32)cc1>>COc1ccc(Cn2c(C)nc3c2C=Cc2ccccc2C3O)cc1,,CCO,ClCCl,[BH4-].[Na+],,test
US20050037925A1,CNOC.Cc1cccc(C2CC2)c1Oc1nnc(Cl)cc1O.O=C(Cl)Cl>>CON(C)C(=O)Oc1cc(Cl)nnc1Oc1c(C)cccc1C1CC1,,Cc1ccccc1,O,Cl,c1ccncc1,test
US20130109661A1,COC(=O)c1cccc(-c2cc(Nc3cccc(N4CCC(C(C)(C)C)C4)n3)c3nccn3n2)c1>>CC(C)(C)C1CCN(c2cccc(Nc3cc(-c4cccc(C(=O)O)c4)nn4ccnc34)n2)C1,,C1COCCO1,O,[Na+].[OH-],,test
US20060270690A1,CCS(=O)(=O)Nc1cccc(C(C)=O)c1.COC(OC)N(C)C>>CCS(=O)(=O)Nc1cccc(C(=O)C=CN(C)C)c1,,CCOC(C)=O,CO,,,test
US20130012499A1,CO.Cc1c(-c2cccc(C(F)(F)F)c2)nc2cc(O)c(F)cc2c1C(=O)O>>COC(=O)c1c(C)c(-c2cccc(C(F)(F)F)c2)nc2cc(O)c(F)cc12,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20160115128A1,CC(C)(C)C(=O)Cl.COc1ncccc1N>>CC(C)(C)CNc1ccc[nH]c1=O,,CC(=O)N(C)C,,O,,test
US05536869,CC(C)(C)OC(=O)CC(N)C#C[Si](C)(C)C.CCO>>CCOC(=O)CC(N)C#C[Si](C)(C)C,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US06281356B1,COC(=O)C(=O)Cl.Cn1ccc2ccc(-n3ccnc3)cc21>>COC(=O)C(=O)c1cn(C)c2cc(-n3ccnc3)ccc12,,ClCCl,,,,test
US20120077989A1,Cc1ccc(C=O)c(Br)c1.N#C[Cu]>>Cc1ccc(C=O)c(C#N)c1,,CN1CCCC1=O,,O,,test
US20030087902A1,C=Cc1ccc2c(c1)c(-c1ccc(C(C)(C)C)cc1)c(C(=O)OCC)n2Cc1cccc(OC)c1.CC(=O)O>>CCOC(=O)c1c(-c2ccc(C(C)(C)C)cc2)c2cc(CCO)ccc2n1Cc1cccc(OC)c1,,C1CCOC1,,[BH4-].[Na+],,test
US04956359,O=C(N1CCN(Cc2ccccc2)CC1)N1CC(Oc2ccc(F)cc2)C1.O=C(O)/C=C/C(=O)O>>O=C(N1CCN(Cc2ccccc2)CC1)N1CC(Oc2ccc(F)cc2)C1.O=C(O)/C=C/C(=O)O,,CC(C)O,,,,test
US20030232930A1,CCCCCCCCCCCCCCCCOC(=O)C=Cc1ccc(O)cc1.OCCCCCCCl>>CCCCCCCCCCCCCCCCOC(=O)C=Cc1ccc(OCCCCCCO)cc1,,CN1CCCC1=O,O,[I-].[K+],,test
US20050080108A1,CCOC(=O)c1c(Cl)c2cc([N+](=O)[O-])ccc2n1C>>CCOC(=O)c1c(Cl)c2cc(N)ccc2n1C,[Ni],CO,Cc1ccccc1,NN,O,test
US20100173880A1,COC(=O)[C@@H](c1ccccc1)N(C)c1ccccc1.Cl>>CN(c1ccccc1)[C@@H](C(=O)O)c1ccccc1.Cl,,C1COCCO1,,O,,test
US20080058320A1,COC(=O)C(C)(C)[C@H]1CCCN(C)C1>>CN1CCC[C@H](C(C)(C)C(=O)O)C1,,CO,,[Na+].[OH-],,test
US05089507,C1CCNC1.CCOC(=O)N1CCCC(C)(C)C1C(=O)O>>CC1(C)CCCNC1C(=O)N1CCCC1,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20120225062A1,C=Cc1cc(F)c(-c2nc(C(=O)Nc3cnccc3[C@H]3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](C)C3)ccc2F)c(F)c1>>CCc1cc(F)c(-c2nc(C(=O)Nc3cnccc3[C@H]3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](C)C3)ccc2F)c(F)c1,[Pd],CO,,,,test
US04457931,CC(C)NC(C)C.CC(Cl)C(=O)Cl>>CC(Cl)C(=O)N(C(C)C)C(C)C,,CO,,,,test
US20060030609A1,CCC(C)N.O=C(O)Cc1cc([N+](=O)[O-])ccc1F>>CCC(C)N1C(=O)Cc2cc([N+](=O)[O-])ccc21,,CS(C)=O,,,,test
US20090192156A1,C1CCN(CCOC2CCNCC2)CC1.O=C(O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F>>O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCC(OCCN2CCCC2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130331397A1,CC(C)(C)OC(=O)N1C[C@H](O)C[C@@H]1c1cc(F)cc(C#N)c1.CCN(CC)S(F)(F)F>>CC(C)(C)OC(=O)N1C[C@@H](F)C[C@@H]1c1cc(F)cc(C#N)c1,,ClCCl,,,,test
US05698691,CC(C)CN1C(=O)CCC(c2ccccc2Cl)c2ccccc21.O=C1CCC(=O)N1Cl>>CC(C)CN1C(=O)CCC(c2ccccc2Cl)c2cc(Cl)ccc21,,CN(C)C=O,,CCOC(C)=O,,test
US20100069383A1,COc1ccc(N(C)c2nc(CN)nc3ccccc23)cc1.O=C1CCC(=O)O1>>COc1ccc(N(C)c2nc(CNC(=O)CCC(=O)O)nc3ccccc23)cc1,,ClCCl,,,,test
US06169087A,CCOC(=O)c1nn(-c2ccc(OC)cc2)c(=O)c2c(N)scc12>>COc1cccc(-n2nc(C(=O)O)c3csc(N)c3c2=O)c1,,O,,CCO,[Na+].[OH-],test
US20160009726A1,C#CCCC.COC(=O)c1ccc(F)c(Br)n1>>CCCC#Cc1nc(C(=O)OC)ccc1F,[Cu]I,CN(C)C=O,,,,test
US20110144110A1,CCOC(=O)CCc1ccc(-c2ccc(Br)cc2)n1-c1ccc(-n2ccnc2)cn1.c1c[nH]cn1>>CCOC(=O)CCc1ccc(-c2ccc(-n3ccnc3)cc2)n1-c1ccc(-n2ccnc2)cn1,[Cu]I,CS(C)=O,O,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US20100130546A1,C1COCCN1.CCCOc1ccc(F)c2c(=O)c(-c3ccc(C(=O)O)cc3)c[nH]c12>>CCCOc1ccc(F)c2c(=O)c(-c3ccc(C(=O)N4CCOCC4)cc3)c[nH]c12,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US06329381B1,BrBr.Nc1nc(OCCCCO)nc2c1ncn2Cc1ccccc1>>Nc1nc(OCCCCO)nc2c1nc(Br)n2Cc1ccccc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20030153595A1,CI.c1cc2cc(C3OCCO3)ncc2[nH]1>>Cn1ccc2cc(C3OCCO3)ncc21,,C1CCOC1,,[H-].[Na+],,test
US20120058988A1,CC(=O)O.CCOC(=O)c1ccc(Nc2ccc(-c3ccc(Cl)c(Cl)c3)cc2C#N)cc1>>CCOC(=O)c1ccc2[nH]c3c(C(N)=O)cc(-c4ccc(Cl)c(Cl)c4)cc3c2c1,CC(=O)O[Pd]OC(C)=O,,,,,test
US20070149561A1,CCNCC.CCn1cc(-c2ccnc3[nH]c(-c4ccc(CN5CCCC5)cc4)cc23)c(-c2ccc(N)cc2)n1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCN(CC)C(=O)Nc1ccc(-c2nn(CC)cc2-c2ccnc3[nH]c(-c4ccc(CN5CCCC5)cc4)cc23)cc1,,C1CCOC1,,,,test
US20020146639A1,C=C(C(=O)O)C(F)(F)F.CC(C)(C)O>>C=C(C(=O)OC(C)(C)C)C(F)(F)F,,ClCCl,ClCCl,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20060084654A1,CC1(C)CCCC(C)(C)N1.Clc1cnccn1.O=Cc1cccc(OCc2ccccc2)c1F.OC(c1cccc(OCc2ccccc2)c1F)c1nccnc1Cl.[Li]CCCC>>Nc1nccn2c(C3CCC3)nc(-c3cccc(OCc4ccccc4)c3F)c12,,C1CCOC1,,CCCCCC,,test
US20150051171A1,Cn1nnn(-c2cccc(C3CC3)c2CBr)c1=O.Oc1ccn(-c2ccc(Br)cc2)n1>>Cn1nnn(-c2cccc(C3CC3)c2COc2ccn(-c3ccc(Br)cc3)n2)c1=O,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US05892048,Cc1ccc(S(=O)(=O)N(C)N=C(Cl)c2c(Cl)cccc2Cl)cc1.N#CCc1ccc(Cl)cc1>>Cn1nc(-c2c(Cl)cccc2Cl)nc1Cc1ccc(Cl)cc1,,Clc1ccccc1Cl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20100256172A1,CC(=O)Nc1cc(Br)ccn1.COc1ccc(CBr)cc1>>COc1ccc(CN(C(C)=O)c2cc(Br)ccn2)cc1,,CCCCCC,CCOC(C)=O,CN(C)C=O,[H-].[Na+],test
US20100056515A1,Cn1c(=O)[nH]c2c(Cl)ccc(C(N)=O)c21>>Cn1c(=O)[nH]c2c(Cl)ccc(C#N)c21,,CN(C)C=O,,O=S(Cl)Cl,O=C([O-])O.[Na+],test
US20050282819A1,CC1(C)C(=O)C(C)(C)c2cc(C(Cl)CCN3CCN(c4nsc5ccccc45)CC3)ccc21>>CC1(C)C(=O)C(C)(C)c2cc(CCCN3CCN(c4nsc5ccccc45)CC3)ccc21,,Cc1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,CCCC[SnH](CCCC)CCCC,test
US20070117760A1,CC(C)c1sc(NC(=O)c2cc(NC(=O)c3cc([N+](=O)[O-])cn3C)cn2C)nc1C(=O)NCCCN(C)C.CCO>>CC(C)c1sc(NC(=O)c2cc(NC(=O)c3cc(NC=O)cn3C)cn2C)nc1C(=O)NCCCN(C)C,[Pd],,,,,test
US05668161,CSc1ccc(C(Br)C(=O)c2ccc(F)cc2)cc1.O=C(OO)c1cccc(Cl)c1>>CS(=O)(=O)c1ccc(CC(=O)c2ccc(F)cc2)cc1,,ClCCl,,O=S([O-])O.[Na+],,test
US20130143863A1,CI.O=C1c2ccc(Cl)cc2CCN1c1cncc(CO)c1>>COCc1cncc(N2CCc3cc(Cl)ccc3C2=O)c1,,C1CCOC1,,[H][H],[H-].[Na+],test
US20020156087A1,CC(=O)OC(C)=O.Nc1nc(Cl)ccc1[N+](=O)[O-]>>CC(=O)Nc1nc(Cl)ccc1[N+](=O)[O-],,C1CCOC1,,[H-].[Na+],,test
US20110319394A1,CCn1c(=O)n(-c2ccc3c(c2)CCN3C(=O)OC(C)(C)C)c2ncccc21>>CCn1c(=O)n(-c2ccc3c(c2)CCN3)c2ncccc21,,CCOC(C)=O,,Cl,,test
US20110306610A1,CCCCOc1nc(N)c2[nH]cnc2n1.COC(=O)c1cccc(OCCBr)c1>>CCCCOc1nc(N)c2ncn(CCOc3cccc(C(=O)OC)c3)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090062280A1,COc1ccc2nc(-c3ccc(CCCOC(C)=O)cc3)c(=O)[nH]c2c1>>COc1ccc2nc(-c3ccc(CCCO)cc3)c(=O)[nH]c2c1,,CO,O,[Na+].[OH-],,test
US20110201632A1,CN[C@@H]1CCCC[C@H]1NC.O=C(O)c1ccccc1I.c1c[nH]nn1>>Cc1ccc(-n2nccn2)c(C(=O)O)c1,[Cu]I,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070129351A1,C1COCCN1.O=Cc1ccc(C(=O)N2CCN(C3CC3)CC2)cc1>>O=C(c1ccc(CN2CCOCC2)cc1)N1CCN(C2CC2)CC1,,ClCCCl,O,[Na+].[OH-],,test
US20090209524A1,CCCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)O)cc1OC.CO>>CCCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1OC,,CO,,Cl,O=C([O-])O.[Na+],test
US20090221654A1,CC(C)(C)[Si](OC[C@H]1[C@@H](F)C[C@@H]2OC(=O)C[C@@H]21)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](OC[C@H]1[C@@H](F)C[C@@H]2OC(O)C[C@@H]21)(c1ccccc1)c1ccccc1,,C1CCOC1,,CC(C)C[AlH]CC(C)C,,test
US20110118326A1,Cc1ccc(S(=O)(=O)Cl)cc1.OC[C@H]1OCC[C@@H]1O>>Cc1ccc(S(=O)(=O)OC[C@H]2OCC[C@@H]2O)cc1,,c1ccncc1,,,,test
US20100261755A1,CC(C)CC1CC(=O)CC(=O)N1>>CC(C)CC1CC(O)CCN1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05840732,O=c1c(Cc2ccccc2)c2n(c(=O)n1Cc1ccccc1)CCCS2>>O=c1[nH]c(=O)n2c(c1Cc1ccccc1)SCCC2,,Cc1ccccc1,,BrB(Br)Br,CO,test
US20150126490A1,CC(C)(C)OC(=O)c1ccc(Br)cc1F.CC1(C)OB(c2cccnc2N)OC1(C)C>>CC(C)(C)OC(=O)c1ccc(-c2cccnc2N)cc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCCCO,CCOC(C)=O,,,test
US20150274777A1,CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)C(=O)NCc1ccccc1>>CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)C(=O)NCc1ccccc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20050020605A1,CCO/N=C(\c1ccc(Br)cc1)C1CCN(C2(C)CCNCC2)CC1.O=C(O)c1cnnc2ccccc12>>CCON=C(c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3cnnc4ccccc34)CC2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05246948,Cl.O=C(Cl)c1ccccc1.c1ccc(CNCCCSc2ccncc2)cc1>>Cl.O=C(c1ccccc1)N(CCCSc1ccncc1)Cc1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
US20060247213A1,CC(=O)O.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)Cc1ccncc1>>CCOC(=O)CC1CCN(C(=O)OCc2ccccc2)CC1,O=[Pt],CC(=O)O,,[H][H],,test
US20060128685A1,CCOC(=O)C(=O)OCC.COc1ccc(C(C)=O)cc1.COc1ccc(NN)cn1>>CCOC(=O)c1cc(-c2ccc(OC)cc2)n(-c2ccc(OC)nc2)n1,,CN(C)C=O,,Cl,[H-].[Na+],test
US05464796,CCOC(=O)C(C(=O)OCC)C(=O)c1c(F)c(F)c(F)c(F)c1Br>>CCOC(=O)CC(=O)c1c(F)c(F)c(F)c(F)c1Br,,O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20140148452A1,Cc1ncccc1O.OC[C@@H]1CN(CCN2CCc3ccccc32)CCO1>>Cc1ncccc1OC[C@@H]1CN(CCN2CCc3ccccc32)CCO1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100168063A1,COC(=O)c1nc2ccc(C)cn2c(=O)c1OCc1ccccc1>>Cc1ccc2nc(C(=O)O)c(OCc3ccccc3)c(=O)n2c1,,CO,,Cl,[Li+].[OH-],test
US20070276009A1,NCc1ccccc1.O=C(O)c1ccc2[nH]c3c(c2c1)CCCC3=O>>O=C(NCc1ccccc1)c1ccc2[nH]c3c(c2c1)CCCC3=O,,C1CCOC1,,ClCCCl,,test
US20160255837A1,CCSc1cc(C(F)(F)F)cnc1C(=O)O.CNc1nnc(Cl)cc1N>>CCSc1cc(C(F)(F)F)cnc1C(=O)Nc1cc(Cl)nnc1NC,,c1ccncc1,,CCN=C=NCCCN(C)C,Cl,test
US20070287724A1,CCCC(OC)(OC)OC.Nc1cnc2ccccc2c1NCC1(O)CCOCC1>>CCCc1nc2cnc3ccccc3c2n1CC1(O)CCOCC1,,Cc1ccccc1,,Cl,c1ccncc1,test
US04370340,ClC1CCCCC1.Clc1ccc(Cl)cc1>>Clc1ccc(Cl)c(C2CCCCC2)c1,,S=C=S,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20040186292A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.O=C(O)Cc1ccccc1>>CC(C)(C)OC(=O)N1CCC(O)(C(C(=O)O)c2ccccc2)CC1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20160214934A1,CCOC(=O)CCBr.Cc1cc(OCCCc2c[nH]c3c(Br)cccc23)cc(C)c1Cl>>CCOC(=O)CCn1cc(CCCOc2cc(C)c(Cl)c(C)c2)c2cccc(Br)c21,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160166560A1,CN(C(=O)n1cnc(-c2cccc(C(N)=O)c2)c1)C1CCN(Cc2ccccc2O)CC1.Cl>>CN(C(=O)n1cnc(-c2cccc(C(N)=O)c2)c1)C1CCN(Cc2ccccc2O)CC1.Cl,,CO,,CCOCC,,test
US20040092582A1,CCOC(=O)CN=C=O.COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(N)c1)=NC(C)(C)C2>>COc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(N3C(=O)CNC3=O)c1)=NC(C)(C)C2,,C1CCOC1,,,,test
US20110237573A1,Brc1ccnnc1.CC1(C)OB(c2ccc(N)nc2)OC1(C)C>>Nc1ccc(-c2ccnnc2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US05985935,COc1ccc(C=CC(=O)c2ccc(O)cc2)c(OC)c1>>COc1ccc(CCC(=O)c2ccc(O)cc2)c(OC)c1,[Pt],CCO,,,,test
US07351719B2,CC1CCN(CCc2ccc(N)cc2Cl)CC1.O=C(O)/C=C/c1ccc(C(F)(F)F)cc1Cl>>CC1CCN(CCc2ccc(NC(=O)/C=C/c3ccc(C(F)(F)F)cc3Cl)cc2Cl)CC1,,CN(C)C=O,,,,test
US20050054631A1,CN(C)C=O.O=C1Cc2ccccc2N1c1ccccn1.O=P(Cl)(Cl)Cl>>O=Cc1c(Cl)n(-c2ccccn2)c2ccccc12,,ClCCl,c1ccncc1,,,test
US20160024009A1,CCI.COC(=O)[C@@H](NS(=O)(=O)c1ccc(F)cc1)C(C)O>>CCN([C@H](C(=O)OC)C(C)O)S(=O)(=O)c1ccc(F)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20070219195A1,CNc1ccc2c(Nc3cc(C)[nH]n3)nn(C(C)C)c(=O)c2c1.COCC(=O)Cl>>COCC(=O)N(C)c1ccc2c(Nc3cc(C)[nH]n3)nn(C(C)C)c(=O)c2c1,,CN(C)C=O,,O,[H-].[Na+],test
US20160214977A1,CCOC(=O)c1ccc(NCC2CC2)c(N)c1.CCn1c2ccc(C=O)cc2c2cc(OC)ccc21>>CCn1c2ccc(OC)cc2c2cc(-c3nc4cc(C(=O)O)ccc4n3CC3CC3)ccc21,,CC(=O)O,,[Cl-].[Na+],,test
US20070203191A1,CC(O)c1ccc(C(F)(F)Cl)nc1.O=S(Cl)Cl>>CC(Cl)c1ccc(C(F)(F)Cl)nc1,,ClCCl,,,,test
US05194440,Cl.N#Cc1ccc(N)cc1.O=N[O-]>>Cl.N#Cc1ccc(NN)cc1,,Cl,O,Cl[Sn]Cl,,test
US20110306607A1,NN.O=C1C(=CO)C2(CCN(C(=O)OCc3ccccc3)CC2)Oc2ccccc21>>O=C(OCc1ccccc1)N1CCC2(CC1)Oc1ccccc1-c1[nH]ncc12,,CCO,,,,test
US06093838,CCOC(=O)c1ccc(N(CC)c2cc(C(C)(C)C)c3c(c2)C(C)(C)CO3)cc1>>CCN(c1ccc(C(=O)O)cc1)c1cc(C(C)(C)C)c2c(c1)C(C)(C)CO2,,CCO,,[K+].[OH-],,test
US04234571,COC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O>>N[C@H](Cc1ccc2ccccc2c1)C(=O)O,,Cl,,,,test
US20150051402A1,CCNCc1cnc(Cl)s1.CCOc1ccc([N+](=O)[O-])c(Cl)n1>>CCOc1ccc([N+](=O)[O-])c(N(CC)Cc2cnc(Cl)s2)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120225867A1,N#Cc1ncc(-c2ccnn2C2CCCCO2)cc1[N+](=O)[O-]>>N#Cc1ncc(-c2ccn[nH]2)cc1[N+](=O)[O-],,CCO,Cl,O,O=C([O-])O.[Na+],test
US20140018345A1,CS(=O)(=O)c1ccc(CC(=O)O)cc1.Cc1c(Br)cnc(N)c1-c1cccc(C(F)(F)F)c1>>Cc1c(Br)cnc(NC(=O)Cc2ccc(S(C)(=O)=O)cc2)c1-c1cccc(C(F)(F)F)c1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20160176869A1,CC(C)O.O=C(O)c1cc(F)c(Cl)nc1Cl>>CC(C)OC(=O)c1cc(F)c(Cl)nc1Cl,CN(C)C=O,C1CCOC1,,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20080312192A1,CNc1nccc(Oc2ccc([N+](=O)[O-])cc2)n1>>CNc1nccc(Oc2ccc(N)cc2)n1,[Ni],CCCCCC,CCOC(C)=O,,,test
US20070249834A1,Brc1cccc(CC(Br)(Cc2cccc(Br)c2)Cc2cccc(Br)c2)c1>>Brc1cccc(CC(Cc2cccc(Br)c2)Cc2cccc(Br)c2)c1,[Zn],CC(=O)O,,,,test
US20120225854A1,CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)C[C@@H]2COS(C)(=O)=O)cc1)C(F)(F)F.O=C1CNCCN1>>CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)C[C@@H]2CN2CCNC(=O)C2)cc1)C(F)(F)F,,CC#N,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20080207703A1,CNCCOC.COc1ccc(CNc2nc(CCl)ns2)c(OC)c1>>COCCN(C)Cc1nsc(NCc2ccc(OC)cc2OC)n1,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04593019,NC1c2ccccc2-c2ccccc21.OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O>>OC[C@H]1O[C@@H](n2cnc3c(Nc4cccc5c4Cc4ccccc4-5)ncnc32)[C@H](O)[C@@H]1O,,CCO,,CCN(CC)CC,Cl,test
US20120196845A1,O=C(Cl)c1ncc(Br)cc1F>>OCc1ncc(Br)cc1F,,C1CCOC1,,CO,[BH4-].[Li+],test
US20110224302A1,CO.COc1cc(F)c(F)cc1CC(=O)O>>COC(=O)Cc1cc(F)c(F)cc1OC,,O,,O=S(=O)(O)O,,test
US20090258901A1,BrCCOCCBr.CCOCC.CS(C)=O.N#CCc1ccc(Cl)cc1>>CC(=O)[O-].N#CC1(c2ccc(Cl)cc2)CCOCC1,,CCOCC,,[H-].[Na+],,test
US08318757B2,Cc1ccc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)cc1Cl.O=C1CCC(=O)N1Br>>FC(F)(F)C1(c2cc(Cl)c(Cl)c(Cl)c2)CC(c2ccc(CBr)c(Cl)c2)=NO1,,ClCCCl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20160096831A1,Cc1ccc(C(C)C)c(N2C(=O)C(c3ccc([N+](=O)[O-])cc3)S/C2=N\C(=O)[O-])c1.NC1CCCCC1c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1>>Cc1ccc(C(C)C)c(N2C(=O)CS/C2=N\C(=O)NC2CCCCC2c2ccc(-c3ncn(-c4ccc(OC(F)(F)F)cc4)n3)cc2)c1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080312255A1,CCOC(=O)c1sc(Cl)nc1-c1cnccn1.Cc1[nH]c(C(=O)N[C@@H]2CCNC[C@@H]2F)c(C#N)c1Cl>>CCOC(=O)c1sc(N2CC[C@@H](NC(=O)c3[nH]c(C)c(Cl)c3C#N)[C@@H](F)C2)nc1-c1cnccn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20030008841A1,COC1CCC(OC)O1.Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>OC[C@H]1O[C@@H](n2cnc3c(-n4cccc4)ncnc32)[C@H](O)[C@@H]1O,,CC(=O)O,,,,test
US20030225127A1,CCOC(=O)CC1(C(C)CNS(=O)(=O)C(C)C)C=CC(c2ccccc2)=CC1[N+](=O)[O-]>>CC(CNS(=O)(=O)C(C)C)C1(CC(=O)O)C=CC(c2ccccc2)=CC1[N+](=O)[O-],,CCO,O,Cl,[Na+].[OH-],test
US20130231328A1,OCCC1CCc2sc3ncnc(Cl)c3c2C1>>OCC[C@H]1CCc2sc3ncnc(Cl)c3c2C1,,CO,,O=C=O,,test
US20090269305A1,NC(=O)CBr.NS(=O)(=O)c1ccccc1O>>NC(=O)COc1ccccc1S(N)(=O)=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060020146A1,COc1cc(C(=O)N(NC(=O)c2ccc3c(c2C)OCCO3)C(C)(C)C)cc(OC)c1OC(C)=O>>COc1cc(C(=O)N(NC(=O)c2ccc3c(c2C)OCCO3)C(C)(C)C)cc(OC)c1O,,CO,,N,,test
US20140228340A1,CC1(C)OB(c2ccc(OCC3CC3)c(C#N)c2)OC1(C)C.Clc1cc(Br)ccn1>>N#Cc1cc(-c2ccnc(Cl)c2)ccc1OCC1CC1,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20100331335A1,CC(=O)Nc1cc(F)cc(Br)c1.Cl>>Cl.Nc1cc(F)cc(Br)c1,,CCO,,,,test
US20100152208A1,COC(=O)CCc1nc2nc(N3CCC(Oc4cc(F)ccc4Br)CC3)sc2c(=O)[nH]1.COCBr>>O=C(O)C(O)Cc1nc2nc(N3CCC(Oc4cc(F)ccc4Br)CC3)sc2c(=O)[nH]1,,C1CCOC1,,[H-].[Na+],,test
US05885985,CC(=O)OC(C)=O.Cl.N=C(Nc1cccc(N)c1)N1CCCC1>>CC(=O)Nc1cccc(NC(=N)N2CCCC2)c1.Cl,,C1CCOC1,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20050266457A1,Br.Cc1c(N)cccc1C(=O)O>>Cc1c(Br)cccc1C(=O)O,,O,,O=N[O-].[Na+],,test
US20130225588A1,COC(=O)Cc1cc2ccc(F)cc2c(-c2ccc(S(=O)(=O)c3c(F)cccc3F)cc2)c1C>>Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2c(F)cccc2F)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20130131039A1,Clc1cc2nccn2c(-c2cn[nH]c2)n1.N#CC=C1CC2(CCC2)C1>>N#CCC1(n2cc(-c3nc(Cl)cc4nccn34)cn2)CC2(CCC2)C1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20090105219A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)CC12CNc3cccc(c31)NC(=O)C2>>CCOC(=O)CC12CC(=O)Nc3cccc(c31)N(C(=O)OC(C)(C)C)C2,,ClCCl,,CCN(CC)CC,,test
US05514719,CCOC(=O)c1ccc(C(F)(F)F)cc1-c1ccc(OC)c(OC)c1>>COc1ccc(-c2cc(C(F)(F)F)ccc2C(=O)O)cc1OC,,CCO,,[Na+].[OH-],,test
US20140343000A1,CC(C)(C)[Si](C)(C)OCCCBr.O=[N+]([O-])c1ccccc1S(=O)(=O)NCCN1CCS(=O)(=O)CC1>>CC(C)(C)[Si](C)(C)OCCCN(CCN1CCS(=O)(=O)CC1)S(=O)(=O)c1ccccc1[N+](=O)[O-],,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100120858A1,CC(C)(C)N.O=Cc1ccccc1F>>CC(C)(C)N=Cc1ccccc1F,,c1ccccc1,,,,test
US20070213330A1,COC(=O)C=Cc1ccc(CN(CCO[Si](C)(C)C(C)(C)C)CCc2c[nH]c3ccccc23)cc1>>CC(C)(C)[Si](C)(C)OCCN(CCc1c[nH]c2ccccc12)Cc1ccc(C=CC(=O)O)cc1,,C1CCOC1,O,[Li]O,,test
US20140221393A1,CCC(CC)n1ncn(-c2ccc(N3CCN(c4ccc(OC)cc4)CC3)cc2)c1=O>>CCC(CC)n1ncn(-c2ccc(N3CCN(c4ccc(O)cc4)CC3)cc2)c1=O,,Br,,,,test
US20090036431A1,BrC(Br)(Br)Br.COc1cc(CO)cc(CBr)c1>>COc1cc(CBr)cc(CBr)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US05665860,CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CC(C)C[C@H](N)C(=O)O,,CO,,C1=CCCCC1,,test
US20100273850A1,CC(C)(C)OC(=O)c1ccc2[nH]ccc2c1.COC(=O)Cc1ccc(F)c(C#N)c1>>COC(=O)Cc1ccc(-n2ccc3cc(C(=O)OC(C)(C)C)ccc32)c(C#N)c1,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US04612376,CCn1c(-c2ccc(OC)c(OC)c2)cc(=Nc2c(C)cc(C)cc2C)n(C)c1=O.Cl>>CCn1c(-c2ccc(OC)c(OC)c2)cc(=Nc2c(C)cc(C)cc2C)n(C)c1=O.Cl,,O,,,,test
US05840974,C#Cc1ccccc1.[O-]Br>>BrC#Cc1ccccc1,,C1CCOC1,,[Cl-].[NH4+],,test
US04112095,Cc1cc2nncn2nc1-c1cccc([N+](=O)[O-])c1>>Cc1cc2nncn2nc1-c1cccc(N)c1,O=[Pt],CCO,,,,test
US20040157836A1,COC(=O)c1c(N)ccc2ccccc12.O=C1CCC(=O)N1Cl>>COC(=O)c1c(N)c(Cl)cc2ccccc12,,CC#N,,,,test
US04440929,O=C(O)c1ncn2c1c(Cl)nc1ccccc12.O=C(OOC(=O)c1ccccc1)c1ccccc1.O=C1CCC(=O)N1Cl>>CCOC(=O)c1nc(Cl)n2c1c(Cl)nc1ccccc12,,ClC(Cl)(Cl)Cl,,,,test
US04511504,CCOC(=O)[C@@H](N)CC(C)C.O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1>>CCOC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1,,CCN(CC)CC,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20060183762A1,CC(C)(C)OC(=O)NN.O=C(O)c1cc(F)c(F)cc1NC1CC1>>CC(C)(C)OC(=O)NNC(=O)c1cc(F)c(F)cc1NC1CC1,,ClCCl,,CCN=C=NCCCN(C)C,,test
US05463149,CCBr.CCCCCCCCCC/C=C\CCCl>>CCCC/C=C\CCCCCCCCCC,,C1CCOC1,,[Mg],[Cl-].[NH4+],test
US20030139390A1,CCOC(=S)S.N#Cc1ccc(Cl)c(N)c1>>N#Cc1ccc2sc(S)nc2c1,,CN(C)C=O,,[K],,test
US04978753,C#CC(=O)OC.NC1=Nc2ccc(Cl)cc2C(c2ccccc2Cl)=NC1>>O=c1ccn2c(n1)CN=C(c1ccccc1Cl)c1cc(Cl)ccc1-2,,CO,,,,test
US20070142649A1,O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3>>O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3,,CS(=O)(=O)O,,,,test
US20110183938A1,C[Si](C)(C)CCOCn1c2cnc(Br)cc2c2cc(I)cnc21>>C[Si](C)(C)CCOCn1c2cnc(Br)cc2c2cccnc21,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20130156756A1,CC(C)(C)N1CCNCC1.COc1cc(F)ccc1Br>>COc1cc(N2CCN(C(C)(C)C)CC2)ccc1Br,,C1CCOC1,,O,[Li]CCCC,test
US20090298794A1,COc1cc([N+](=O)[O-])ccc1OC[C@H](O)C1CC1>>COc1cc(N)ccc1OC[C@H](O)C1CC1,[Pd],CCO,,,,test
US05491152,CCCCC(Cc1ccc(OC)c(OC)c1)C(=O)OCC>>CCCCC(CO)Cc1ccc(OC)c(OC)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100144745A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N[C@H]1CCC[C@H](CO)C1>>CC(=O)OC[C@H]1CCC[C@H](NC(=O)OC(C)(C)C)C1,,ClCCl,,c1ccncc1,,test
US20140142114A1,FC(F)(F)c1ccc(N2CCNCC2)cc1.O=C(Cl)CCl>>O=C(CCl)N1CCN(c2ccc(C(F)(F)F)cc2)CC1,,ClCCl,,CCN(CC)CC,,test
US04898874,Cc1ccc(-c2onc3ccccc23)cc1.O=C1CCC(=O)N1Br>>BrCc1ccc(-c2onc3ccccc23)cc1,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20020086890A1,CC#CCOc1ccc(S(=O)(=O)C2(C(=O)OC)CCN(C(=O)c3cccs3)CC2)cc1>>CC#CCOc1ccc(S(=O)(=O)C2(C(=O)O)CCN(C(=O)c3cccs3)CC2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20030078251A1,COC(=O)CCc1cc(NC(=O)C[C@H]2O[C@@H](c3cccc(C)c3C)c3cc(Cl)ccc3N(CC(C)(C)COC(C)=O)C2=O)ccc1F>>CCC(C)C[C@@H]1O[C@H](CC(=O)Nc2ccc(F)c(CCC(=O)O)c2)C(=O)N(CC(C)(C)CO)c2ccc(Cl)cc21,,O,,CCO,[Na+].[OH-],test
US05346913,C#CCBr.CC1(C)NC(=O)NC1=O>>C#CCN1C(=O)NC(C)(C)C1=O,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20020169192A1,CCCCCCCN(CCc1cccc(OCC(=O)OCC)c1)C(=O)Nc1ccc(OC)cc1OC>>CCCCCCCN(CCc1cccc(OCC(=O)O)c1)C(=O)Nc1ccc(OC)cc1OC,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20010044538A1,CC(C)(C)OC(=O)n1c(-c2ccncc2)c(-c2ccc(F)cc2)c2ncccc21.CSSC>>CSc1ccnc2c(-c3ccc(F)cc3)c(-c3ccncc3)n(C(=O)OC(C)(C)C)c12,,C1CCOC1,,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US05236931,COC(=O)c1cc(Cl)c(N)cc1O.Cc1nc(CCl)cs1>>Cc1nc(COc2cc(N)c(Cl)cc2C(=O)O)cs1,,CN(C)C=O,,O,[H-].[Na+],test
US20080176829A1,CC(C)(C)OC(=O)N1CCOc2ccc3[nH]cc(Cl)c3c2C1.O=C(O)C(F)(F)F.O=S(=O)(Cl)c1ccc(F)cc1>>O=C(O)C(F)(F)F.O=S(=O)(c1ccc(F)cc1)n1cc(Cl)c2c3c(ccc21)OCCNC3,,CN(C)C=O,,[H-].[Na+],,test
US04216148,CN1CCNCC1.O=C1Nc2cscc2Nc2ccc(F)cc21>>CN1CCN(C2=Nc3cscc3Nc3ccc(F)cc32)CC1,Cl[Ti](Cl)(Cl)Cl,Cc1ccccc1,,COc1ccccc1,,test
US20130142754A1,CC1C=C[C@@H]2C[C@@]2(C(=O)NS(=O)(=O)C2CC2)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)OC(C)(C)C)[C@H](C)CCC1.COc1cnc(Cl)c2cccc(Cl)c12>>COc1cnc(O[C@@H]2C[C@H]3C(=O)N[C@]4(C(=O)NS(=O)(=O)C5CC5)C[C@H]4C=CC(C)CCC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N3C2)c2cccc(Cl)c12,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20100160280A1,Fc1ncccc1-c1ccnc(C(F)(F)F)c1.Oc1ccc(Nc2ccccn2)cc1>>FC(F)(F)c1cc(-c2cccnc2Oc2ccc(Nc3ccccn3)cc2)ccn1,,CS(C)=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110269791A1,CI.C[C@]12CCN(C(=O)C3CCCC3)[C@@H](Cc3ccc(O)cc31)C2>>COc1ccc2c(c1)[C@]1(C)CCN(C(=O)C3CCCC3)[C@@H](C2)C1,,C1CCOC1,O,CN(C)C=O,[H-].[Na+],test
US20120202785A1,C[C@H](N)c1nc2ccccc2n1-c1ccccc1.Cc1c[nH]c2ncnc(Cl)c12>>Cc1c[nH]c2ncnc(N[C@@H](C)c3nc4ccccc4n3-c3ccccc3)c12,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20140171429A1,CC(C)(C)OC(=O)N1CCN(c2ccc(N)cc2)CC1.O=c1[nH]ccc2cc(Cl)nc(Cl)c12>>CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3nc(Cl)cc4cc[nH]c(=O)c34)cc2)CC1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20090012129A1,CCOCCOc1cc(C(=O)OC)ccc1I>>CCOCCOc1cc(CO)ccc1I,,C1CCOC1,,Cl,[BH4-].[Li+],test
US04090026,Cc1[nH]cnc1CSCCN.S=C=S>>Cc1[nH]cnc1CSCCNC(=S)S,,CCO,,,,test
US20100081692A1,O=C(O)c1ccc(F)cc1O>>OCc1ccc(F)cc1O,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100210672A1,COc1ncc(B(O)O)c(OC)n1.Cc1nc(I)sc1C>>COc1ncc(-c2nc(C)c(C)s2)c(OC)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,ClCCl,O=C([O-])O.[Na+],,test
US20080188498A1,CC(C)(C)OC(=O)N1CCC(OCc2ccccc2)C1COS(C)(=O)=O.[I-]>>CC(C)(C)OC(=O)N1CCC(OCc2ccccc2)C1CI,,CC(C)=O,,CCOC(C)=O,,test
US20080090794A1,Brc1ccccn1.CON(C)C(=O)C(c1ccccc1)N1CCOCC1>>O=C(c1ccccn1)C(c1ccccc1)N1CCOCC1,,C1CCOC1,,[Li]C(C)(C)C,,test
US06538015B1,CC(C)n1nc(CN=[N+]=[N-])c(Cc2ccncc2)c1Sc1cc(Cl)cc(Cl)c1>>CC(C)n1nc(CN)c(Cc2ccncc2)c1Sc1cc(Cl)cc(Cl)c1,[Pd],CCOC(C)=O,,,,test
US20090181965A1,O=C(C1CCCCC12OCCO2)N1CCOCC1>>O=C1CCCCC1C(=O)N1CCOCC1,O=S(=O)(O)O,CCO,CCOC(C)=O,,,test
US20120238559A1,C[Sn](C)(C)c1cc(N)c2cnn(S(=O)(=O)c3ccccc3)c2c1.Cc1ccc(S(=O)(=O)n2ncc3cc(Br)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2ncc3cc(-c4cc(N)c5cnn(S(=O)(=O)c6ccccc6)c5c4)cnc32)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US20110053909A1,CCCCN(CCNCCc1ccc(O)c2c1OCC(=O)N2)C(=O)CCOCCc1cccc(CCN2CCC3(CC2)CN(C(=O)c2csc(C(C)C)n2)CCO3)c1.O=S(=O)(O)O>>CCCCN(CCNCCc1ccc(O)c2c1OCC(=O)N2)C(=O)CCOCCc1cccc(CCN2CCC3(CC2)CN(C(=O)c2csc(C(C)C)n2)CCO3)c1.O=S(=O)(O)O,,CC#N,CCO,O,,test
US20160194315A1,COC(=O)c1ccnc2cc(C(O)C3CC3)[nH]c12>>O=C(O)c1ccnc2cc(C(O)C3CC3)[nH]c12,,CC#N,O,,,test
US20100249095A1,CC(C)(C)OC(=O)N1CCC2(CCC(OS(C)(=O)=O)CC2)CC1.c1c[nH]cn1>>CC(C)(C)OC(=O)N1CCC2(CCC(n3ccnc3)CC2)CC1,,CN(C)C=O,O,[H-].[Na+],,test
US20120157434A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cn1nnc(-c2ccc(Br)cn2)n1>>Cn1nnc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cn2)n1,,CS(C)=O,,CC(=O)[O-].[K+],,test
US20040023974A1,CCC(CC)CO.O=C(Cl)c1ccc(CBr)cc1>>CCC(CC)COC(=O)c1ccc(CBr)cc1,,ClCCl,,,,test
US05021431,NCCCc1c[nH]cn1.O=C(N=C1NCC(COc2cccc(CN3CCCCC3)c2)O1)c1ccccc1>>O=C(NC(=NCCCc1c[nH]cn1)NCC(O)COc1cccc(CN2CCCCC2)c1)c1ccccc1,,c1ccncc1,,,,test
US03974212,CC(C)C(=O)Cl.COc1cccc(Cl)c1Cl>>COc1ccc(C(=O)C(C)C)c(Cl)c1Cl,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20030096853A1,Cc1ccccc1C#CC(=O)C(F)(F)F.NNc1ccc(S(N)(=O)=O)cc1>>Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1,,O,,CCO,Cl,test
US05731890,CC(C)(C)C(=C(c1ccc([N+](=O)[O-])cc1)C(C)(C)C)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)C(=C(c1ccc([N+](=O)[O-])cc1)C(C)(C)C)c1ccc(N)cc1,[Pd],C1CCOC1,,C1=CCCCC1,,test
US20130059801A1,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O.COCCOCCOCCN>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCOCCOCCOC,,ClCCl,,ClCCCl,,test
US20090023745A1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.O=C(Nc1[nH]nc2c1CN(S(=O)(=O)c1cc(F)cc(F)c1)CC2)C(F)(F)F>>O=C(Nc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2c1CN(S(=O)(=O)c1cc(F)cc(F)c1)CC2)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US06251921B1,COC(=O)[C@@H](N)COc1ccc(-c2sc3cc(O)ccc3c2Cc2ccc(CN3CCCC3)c(OC)c2)cc1>>COc1cc(Cc2c(-c3ccc(OC[C@@H](N)CO)cc3)sc3cc(O)ccc23)ccc1CN1CCCC1,,C1CCOC1,ClCCl,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110301143A1,CCc1ccc(F)cc1C(=O)C1CCN(c2cc(-c3nnn(CC(=O)OC(C)(C)C)n3)on2)CC1>>CCc1ccc(F)cc1C(=O)C1CCN(c2cc(-c3nnn(CC(=O)O)n3)on2)CC1,,O,,O=CO,,test
US20120295884A1,CN(C)CCN(C)Cc1cc(Cl)c(F)c(CNC(=O)OC(C)(C)C)c1>>CN(C)CCNCc1cc(Cl)c(F)c(CN)c1,,C1COCCO1,,Cl,,test
US04000193,ClCCCCOC1CCCCO1.NC(=O)c1cc(C(=O)CN(Cc2ccccc2)Cc2ccccc2)ccc1O>>NC(=O)c1cc(C(=O)CN(Cc2ccccc2)Cc2ccccc2)ccc1OCCCCOC1CCCCO1,,CCC(C)=O,,[Na],,test
US05656629,N#Cc1c(Cc2ccccc2)nn(C2CCCC2)c1N.O=C(Cl)Cc1ccccc1>>N#Cc1c(Cc2ccccc2)nn(C2CCCC2)c1NC(=O)Cc1ccccc1,,ClC(Cl)Cl,,c1ccncc1,,test
US04377576,C1CCNCC1.O=C1Nc2ccccc2N(C(=O)CCCl)c2ccccc21>>Cl.O=C1Nc2ccccc2N(C(=O)CCN2CCCCC2)c2ccccc21,,CC(C)O,,,,test
US20040014773A1,BrC(Br)(Br)Br.O=c1[nH]c(NCc2ccc(Cl)c(Cl)c2)nc2ncn(CCCCO)c12>>O=c1[nH]c(NCc2ccc(Cl)c(Cl)c2)nc2ncn(CCCCBr)c12,,CC#N,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04147799,CC(C)NCC(=O)c1ccc(O)c(O)c1>>CC(C)NCC(=O)c1ccc(O)c(O)c1,,O,,Cl,O=C([O-])O.[Na+],test
US20130059834A1,CCCC[Sn](Cl)(CCCC)CCCC.Cn1nc(I)c2c1CCCC2>>CCCC[Sn](CCCC)(CCCC)c1nn(C)c2c1CCCC2,,C1CCOC1,,CC(C)[Mg]Cl,,test
US04985419,C1CCNC1.CC(COS(C)(=O)=O)N1c2ccc(Cl)cc2Sc2ccc(C#N)cc21>>CC(CN1CCCC1)N1c2ccc(Cl)cc2Sc2ccc(C#N)cc21,,Cc1ccccc1,,,,test
US20030078271A1,C1CCNCC1.Clc1cc(Cl)nc(Cl)n1>>Clc1cc(N2CCCCC2)nc(Cl)n1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20070003680A1,CCI.OCc1cncc(Br)c1>>CCOCc1cncc(Br)c1,,CS(C)=O,O,[K+].[OH-],,test
US20010039343A1,CC(C)C(=O)O.CCOC(=O)C(I)OC(=O)SCC>>CCOC(=O)C(OC(=O)SCC)OC(=O)C(C)C,,C1CCOC1,CCOCC,CCN(C(C)C)C(C)C,,test
US20110312963A1,CC(C)(COCc1ccccc1)C(=O)CC#N.Cc1ccc(NN)cc1>>Cc1ccc(-n2nc(C(C)(C)COCc3ccccc3)cc2N)cc1,,CCO,,Cl,O=C([O-])O.[Na+],test
US20100234365A1,CI.O=C1NCC(c2cccc(C(F)(F)F)c2)N1c1ccc(Oc2ccc(Cl)cc2)cc1>>CN1CC(c2cccc(C(F)(F)F)c2)N(c2ccc(Oc3ccc(Cl)cc3)cc2)C1=O,,CN(C)C=O,,[H-].[Na+],,test
US20060154926A1,CC(C)(C)c1ccc(CBr)cc1.CC(C)CC(=O)N1C(=O)OC[C@H]1Cc1ccccc1>>CC(C)[C@@H](Cc1ccc(C(C)(C)C)cc1)C(=O)N1C(=O)OC[C@H]1Cc1ccccc1,,C1CCOC1,,[Cl-].[NH4+],C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US06569888B1,CC(=O)OC(C)=O.COC(=O)c1cc2c(O)c(OC)ccc2[nH]1>>COC(=O)c1cc2c(OC(C)=O)c(OC)ccc2[nH]1,CN(C)c1ccncc1,,,,,test
US20100168421A1,Cc1ccc(CN(C(=O)OCc2ccccc2)C2CCN(C(=O)[C@@H](NC(=O)[C@H](CC3CCCC3)CN(C=O)OCc3ccccc3)C(C)(C)C)CC2)cc1>>Cc1ccc(CC2CCN(C(=O)[C@@H](NC(=O)[C@H](CC3CCCC3)CN(O)C=O)C(C)(C)C)CC2)cc1,[Pd],,,CCO,[H][H],test
US20060189666A1,CN(C)C=O.Fc1ccc(-c2cnco2)cc1>>O=Cc1ncc(-c2ccc(F)cc2)o1,,C1CCOC1,CCOCC,Cl,[Li]CCCC,test
US04814332,CNC.CSc1n(N=Cc2ccc(N(C)C)cc2)cc[n+]1N=Cc1ccc(N(C)C)cc1.F[B-](F)(F)F>>CN(C)c1ccc(C=Nn2cc[n+](N=Cc3ccc(N(C)C)cc3)c2N(C)C)cc1.F[B-](F)(F)F,,CCOCC,,CN(C)C=O,,test
US06498251B1,c1ccc(CN2CCc3occc3C2)cc1>>c1cc2c(o1)CCNC2,[Pd],CCO,,[H][H],,test
US04631278,N#C[Cu]C#N.O=c1cnn(-c2ccc(C(Cl)c3ccc(Cl)cc3)c(Cl)c2)c(=O)[nH]1>>N#CC(c1ccc(Cl)cc1)c1ccc(-n2ncc(=O)[nH]c2=O)cc1Cl,,CO,ClC(Cl)Cl,,,test
US20150299224A1,CSc1nccc(=O)[nH]1.O=C1CCC(=O)N1I>>CSc1ncc(I)c(=O)[nH]1,,ClC(Cl)Cl,,,,test
US04009200,ClC1=C(Cl)C(Cl)(Cl)C(Cl)=C1Cl.O=C1C=CC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)C2C1C1(Cl)C(Cl)=C(Cl)C2(Cl)C1(Cl)Cl,,Cc1ccccc1,,,,test
US20090118305A1,Brc1cn[nH]c1.CC(C)(C)OC(=O)N1CCC(=CC#N)CC1>>CC(C)(C)OC(=O)N1CCC(CC#N)(n2cc(Br)cn2)CC1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20020103211A1,CC(=O)O[C@H](C)CCCCn1c(=O)c2c(nc(CN)n2Cc2ccccc2)n(C)c1=O.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(=O)O[C@H](C)CCCCn1c(=O)c2c(nc(CNOC(=O)C(F)(F)F)n2Cc2ccccc2)n(C)c1=O,,ClC(Cl)Cl,,,,test
US05466687,O=C(Cl)c1ccc(Cl)cc1.O=C1CCNCC1>>O=C1CCN(C(=O)c2ccc(Cl)cc2)CC1,,C1CCOC1,O,Cl,O=C([O-])[O-].[K+].[K+],test
US04851387,CC(C)CNC(=O)C(=C[C@@H]1OC(C)(C)N(C(=O)OCc2ccccc2)[C@H]1CC(C)C)CC(C)OC1CCCCO1>>CC(C)CNC(=O)C(CC(C)OC1CCCCO1)C[C@H](O)[C@@H](N)CC(C)C,[Pd],CCO,,[H][H],,test
US03998834,BrCCc1ccccc1.Cc1ccc(NC2(C(N)=O)CCNCC2)cc1>>Cc1ccc(NC2(C(N)=O)CCN(CCc3ccccc3)CC2)cc1,,CC(=O)N(C)C,,CCN(CC)CC,,test
US03935223,CCOC(=O)CC(=N)N.O=C1CCCC(=O)C1.O=Cc1ccccc1-c1ccccc1>>CCOC(=O)C1=C(N)NC2=C(C(=O)CCC2)C1c1ccccc1-c1ccccc1,,CCO,,,,test
US20110257179A1,COc1ccc(Cn2cc(-c3nc(Nc4cccc(C#N)n4)sc3C)cn2)cc1>>Cc1sc(Nc2cccc(C#N)n2)nc1-c1cn[nH]c1,,O=C(O)C(F)(F)F,,CO,ClCCl,test
US20060111362A1,CC(C)(C)OC(=O)N1CCN(c2nccc3c2n(Cc2ccccc2)c(=O)n3Cc2ccccc2C#N)CC1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N1CCN(c2ncc(Br)c3c2n(Cc2ccccc2)c(=O)n3Cc2ccccc2C#N)CC1,,CC#N,O,CCOC(C)=O,O=C([O-])O.[Na+],test
US20040044057A1,CCOC(=O)/C=C/Cc1cccc(OC)c1Cc1ccccc1>>CCOC(=O)CCCc1cccc(OC)c1Cc1ccccc1,[Pd],CCO,,[H][H],,test
US20040241706A1,BrCc1ccccc1.Nc1nc(Cl)c2[nH]cnc2n1>>Nc1nc(Cl)c2ncn(Cc3ccccc3)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05324747,CCCCCCCCCC(=O)Oc1ccc([N+](=O)[O-])cc1OC(=O)CCCCCCCCC>>CCCCCCCCCC(=O)Oc1ccc(N)cc1OC(=O)CCCCCCCCC,[Pd],C1CCOC1,CCOC(C)=O,[H][H],,test
US20090137549A1,CCOC(=O)C1CCCNC1.CS(=O)(=O)Nc1ccccc1C(=O)O>>CCOC(=O)C1CCCN(C(=O)c2ccccc2NS(C)(=O)=O)C1,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20090239810A1,Br.OCc1ccc(-c2ccccc2)cc1>>BrCc1ccc(-c2ccccc2)cc1,,O,,,,test
US20150239900A1,Clc1ccc2cnccc2c1.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1ccc2cc(Cl)ccc2c1,,ClCCl,,,,test
US06821992B1,Cc1ccccc1CCC(=O)Cl.NCc1ncc(C(F)(F)F)cc1Cl>>Cc1ccccc1CCC(=O)NCc1ncc(C(F)(F)F)cc1Cl,,C1CCOC1,,CCN(CC)CC,Cl,test
US05741811,CC(=O)OC(C)=O.O=Cc1ccc(-c2ccc(CO)s2)s1>>CC(=O)OCc1ccc(-c2ccc(C=O)s2)s1,,O,,CCOC(C)=O,c1ccncc1,test
US20080119518A1,C=CCc1cc([N+](=O)[O-])ccc1O.CI>>C=CCc1cc([N+](=O)[O-])ccc1OC,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20140113884A1,CC(C)(C)[Si](OCCCCCO)(c1ccccc1)c1ccccc1.II>>CC(C)(C)[Si](OCCCCCI)(c1ccccc1)c1ccccc1,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020037905A1,O=[N+]([O-])c1ccccc1-c1nncn1O>>Nc1ccccc1-c1nncn1O,[Pd],CCO,,,,test
US20140371201A1,COc1cc(Br)c(Cl)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccncn3)ccc21.Cc1cc(B(O)O)ccc1Cl>>COc1cc(-c2ccc(Cl)c(C)c2)c(Cl)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccncn3)ccc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US04931452,N#CCBr.Oc1ncc(C(F)(F)F)cc1Cl>>N#CCn1cc(C(F)(F)F)cc(Cl)c1=O,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100130446A1,C1CCOC1.O=Cc1cnc(C2OCCO2)s1>>CC(O)c1cnc(C2OCCO2)s1,,C1CCOC1,,O=C(O)CC(O)(CC(=O)O)C(=O)O,,test
US20030114505A1,CNC(C)=CC(=O)OC.O=C(Cl)c1ccc(CCl)cc1>>COC(=O)c1c(C)noc1-c1ccc(CCl)cc1,,C1CCOC1,,c1ccncc1,,test
US08569495B2,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](CCC(=O)N2CCN(c3ccc(C(F)(F)F)cc3)CC2)CC1.O=[N+]([O-])c1ccc(F)cc1C(F)(F)F>>O=C(CC[C@@H]1CC[C@@H](Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)CC1)N1CCN(c2ccc(C(F)(F)F)cc2)CC1,,CS(C)=O,ClCCl,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US06326386B1,CC1CCCCN1C(=O)c1cc(Cl)cc(OCCN(C(=O)OC(C)(C)C)c2ccncc2)c1.O=C(O)C(F)(F)F>>CC1CCCCN1C(=O)c1cc(Cl)cc(OCCNc2ccncc2)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20130225552A1,O=[N+]([O-])c1cccnc1NC1CCN(c2nc3ccccc3s2)CC1>>Nc1cccnc1NC1CCN(c2nc3ccccc3s2)CC1,[Pd],CO,,,,test
US20110092698A1,C[C@@H](Nc1ccc(C(F)(F)F)c(Cl)c1)C(=O)O>>C[C@H](CO)Nc1ccc(C(F)(F)F)c(Cl)c1,,C1CCOC1,,,,test
US03966938,CN1CC[C@H](NC(=O)c2ccccc2)[C@H](c2ccc3c(c2)OCO3)C1>>CN1CC[C@@H]2N=C(c3ccccc3)c3cc4c(cc3[C@@H]2C1)OCO4,,O=P(Cl)(Cl)Cl,,,,test
US20160039825A1,CS(N)(=O)=O.O=C(Cl)c1cc2n(n1)CCCN(C(=O)OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C2>>CS(=O)(=O)NC(=O)c1cc2n(n1)CCCN(C(=O)OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C2,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070049593A1,CC(C)(C)OC(=O)n1cccc1B(O)O.COC(=O)c1ccc2c(C3CCCCC3)c(Br)[nH]c2c1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3cccn3C(=O)OC(C)(C)C)[nH]c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US05891902,CI.O=S(=O)(NC(c1ccccc1)c1ccccc1)c1cc2ccccc2n1S(=O)(=O)c1ccccc1>>CN(C(c1ccccc1)c1ccccc1)S(=O)(=O)c1cc2ccccc2n1S(=O)(=O)c1ccccc1,,CN(C)C=O,O,[H-].[Na+],[Cl-].[NH4+],test
US20090149456A1,CN(C)CCNCc1cccc([N+](=O)[O-])c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CN(C)CCN(Cc1cccc([N+](=O)[O-])c1)C(=O)C(F)(F)F,,ClCCl,,,,test
US04672062,CNC1COc2ccccc2C(O)C1>>CNC1C=Cc2ccccc2OC1,,Cl,,N,,test
US20140024666A1,CCC(C)(C)N.O=C(Cl)CC(=O)Cl.O=C=NC1CCCCC1>>CCC(C)(C)N1C(=O)CC(=O)N(C2CCCCC2)C1=O,,ClC(Cl)Cl,,,,test
US20110003787A1,COC[C@H](C)Oc1cc(Oc2ccc(S(=O)(=O)N(Cc3ccc(OC)cc3)Cc3ccc(OC)cc3)nc2)cc(-c2ccc(C3=NC[C@H](C)O3)[nH]2)c1>>COC[C@H](C)Oc1cc(Oc2ccc(S(N)(=O)=O)nc2)cc(-c2ccc(C3=NC[C@H](C)O3)[nH]2)c1,,O=C(O)C(F)(F)F,,,,test
US06291475B1,CCN=C=O.N#Cc1ccc(O)c(N)c1>>CCNC(=O)Nc1cc(C#N)ccc1O,,CC#N,,,,test
US20150175604A1,Cc1nnc2ccc3c(cc(C(=O)OCc4cccc(CO[Si](c5ccccc5)(c5ccccc5)C(C)(C)C)c4)n3Cc3cccc(CO[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)c3)n12.Cl>>Cc1nnc2ccc3c(cc(C(=O)OCc4cccc(CCl)c4)n3Cc3cccc(CO)c3)n12,,C1COCCO1,,,,test
US20070049578A1,COC(=O)C1CN(C(=O)OC(C)(C)C)CCN1C(=O)C=Cc1cccc(Cl)c1>>COC(=O)C1CNCCN1C(=O)C=Cc1cccc(Cl)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05604229,CC(=O)OCCc1ccccc1.CCCCCCCCCC(=O)Cl>>CCCCCCCC(=O)c1ccc(CCOC(C)=O)cc1,,CC(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120022109A1,CC(C)(C)OC(=O)CBr.COCCNCc1ccc(C#N)cc1>>COCCN(CC(=O)OC(C)(C)C)Cc1ccc(C#N)cc1,,CC#N,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20120058989A1,CC(C)(C)OC(=O)CC[C@H](N)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C.CCOC(=O)c1cn(C2CC2)c2c(C=O)c(F)c(F)cc2c1=O>>CCOC(=O)c1cn(C2CC2)c2c(C=O)c(N[C@H](CO)CCC(=O)OC(C)(C)C)c(F)cc2c1=O,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US20020188120A1,CCCCOc1ccc(S(=O)(=O)C2(C(=O)OCC)CCN(Cc3ccc(C)cc3)CC2)cc1>>CCCCOc1ccc(S(=O)(=O)C2(C(=O)O)CCN(Cc3ccc(C)cc3)CC2)cc1,,C1CCOC1,,CO,[Na+].[OH-],test
US20090298807A1,CCOC(=O)C(C)(C)CCCCCCO[Si](C)(C)C(C)(C)C>>CC(C)(CO)CCCCCCO[Si](C)(C)C(C)(C)C,,CCOCC,,CC(C)C[Al+]CC(C)C.[H-],,test
US20150011533A1,CC(C)OC(=O)N=NC(=O)OC(C)C.CC(C)[Si](C(C)C)(C(C)C)n1ccc2c(F)c(O)ccc21.CO>>COc1cnc2c(ccn2[Si](C(C)C)(C(C)C)C(C)C)c1F,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090227622A1,CS(=O)(=O)c1ccc(-c2ccn3c(-c4ccc(CN)cc4)cnc3c2)cc1.O=C=Nc1cccc(C(F)(F)F)c1>>CS(=O)(=O)c1ccc(-c2ccn3c(-c4ccc(CNC(=O)Nc5cccc(C(F)(F)F)c5)cc4)cnc3c2)cc1,,CS(C)=O,,CCN(C(C)C)C(C)C,CO,test
US04080502,BrBr.CN1C(=O)N(C2CCCCC2)CN(C2CCCCC2)C1=O>>CN1C(=O)N(C2CCCCC2)C[NH+](C2CCCCC2)C1=O.[Br-],,ClCCl,,,,test
US05486612,C1CCNCC1.COC(=O)c1cccc(C)c1[N+](=O)[O-].COC(OC)N(C)C>>N#CCCc1cccc2cc[nH]c12,,CN(C)C=O,,O,,test
US20130338137A1,CC(C)(C)OC(=O)NC1CN(c2nc(-c3nn(Cc4ccccc4F)c4ncccc34)nc3c2C(C)(C)C(=O)N3)C1>>CC1(C)C(=O)Nc2nc(-c3nn(Cc4ccccc4F)c4ncccc34)nc(N3CC(N)C3)c21,,CCOCC,,Cl,,test
US20040097732A1,CCCCC1COC(=O)C1.Nc1ccccc1>>CCCCC(CO)CC(=O)Nc1ccccc1,,Cc1ccccc1,,C[Al](C)C,,test
US20060178360A1,C=Cc1ccncc1.CN1CCNCC1>>CN1CCN(CCc2ccncc2)CC1,,CCO,,CC(=O)O,[Na+].[OH-],test
US20150087585A1,CCN(C)C(=O)[C@@H]1CCCNC1.Nc1nc(Cl)ccc1[N+](=O)[O-]>>CCN(C)C(=O)[C@@H]1CCCN(c2ccc([N+](=O)[O-])c(N)n2)C1,,CS(C)=O,,CCN(CC)CC,,test
US20020133015A1,COC(=O)[C@H](Cc1ccc(-c2c(C)ccn(C)c2=O)cc1)NC(=O)OC(C)(C)C.Cl>>COC(=O)[C@@H](N)Cc1ccc(-c2c(C)ccn(C)c2=O)cc1.Cl,,C1COCCO1,,,,test
US03956334,BrCCCCCBr.CC(C)(CO)Oc1ccc(-c2ccc(N)cc2)cc1>>CC(C)(CO)Oc1ccc(-c2ccc(NCCCCCBr)cc2)cc1,,CCCCO,,O=C([O-])[O-].[K+].[K+],,test
US20150361100A1,CC(Nc1ncnc(N)c1C=O)c1cc2ccccn2c1-c1ccccn1>>CC(Nc1ncnc(N)c1CO)c1cc2ccccn2c1-c1ccccn1,,CO,,[BH4-].[Na+],,test
US20050222213A1,CCOC(=O)C(C)c1cccc(C(F)(F)F)c1.O=C1CCC(=O)N1Br>>CCOC(=O)C(C)(Br)c1cccc(C(F)(F)F)c1,,ClC(Cl)(Cl)Cl,,,,test
US06514964B1,COC(=O)CCCC(=O)CBr.NC(N)=S>>COC(=O)CCCC1=CSC(N)N1,,CCO,CCOC(C)=O,,,test
US20040102450A1,CI.O=C1CN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CCN1Cc1cc2cnccc2[nH]1>>Cn1c(CN2CCN(S(=O)(=O)c3cc4ccc(Cl)cc4s3)CC2=O)cc2cnccc21,,CN(C)C=O,,[H-].[Na+],,test
US20040266774A1,COC(=O)c1ccc(-c2ccc(F)cc2)s1>>O=C(O)c1ccc(-c2ccc(F)cc2)s1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20010034051A1,CCN(C(C)C)C(C)C.N#Cc1ccc(NCCN)nc1.O=[N+]([O-])c1ncc(Br)nc1-c1ccc(Cl)cc1Cl>>N#Cc1ccc(NCCNc2cnc([N+](=O)[O-])c(-c3ccc(Cl)cc3Cl)n2)cc1,,CN(C)C=O,,,,test
US20090247505A1,CC[Si](C#CC[C@@H](C)COC1CCCCO1)(CC)CC>>CC[Si](C#CC[C@@H](C)CO)(CC)CC,,C1CCOC1,,Cl,[Na+].[OH-],test
US20120238541A1,COCCBr.O=c1c(I)c(-c2ccccc2)oc2c(=O)[nH]ccc12>>COCCn1ccc2c(=O)c(I)c(-c3ccccc3)oc2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05550147,CS(=O)(=O)c1ccc(-c2cc(C(F)F)nn2-c2ccc(C(N)=O)cc2)cc1>>CSc1ccc(-c2cc(C(F)F)nn2-c2ccc(C#N)cc2)cc1,,CN(C)C=O,,O=P(Cl)(Cl)Cl,,test
US20140154186A1,Cc1c(Br)c[nH]c1C=O.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)n2cc(Br)c(C)c2C=O)cc1,,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US04166862,CCC(C)Br.O=c1c(-c2ccccc2)coc2cc(O)ccc12>>CCC(C)Oc1ccc2c(=O)c(-c3ccccc3)coc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04657913,CCOC(=O)c1cn(CC)c2c(F)c(F)c(F)c(F)c2c1=O>>CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(F)c(F)c21,,O,,CC(=O)O,Cl,test
US20160024077A1,C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OC)c(C)cn3nc(-c4cccc(-c5cc(C#N)ccc5O)c4)cc23)CC1.C=CC[C@@H](C)O>>C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OC)c(C)cn3nc(-c4cccc(-c5cc(C#N)ccc5O[C@@H](C)CC=C)c4)cc23)CC1,,C1CCOC1,O,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070244095A1,Cl.Cn1nnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H]2CCCN(Cc3ccncc3)c3cc4c(cc32)COC4)n1>>Cl.Cn1nnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)[C@H]2CCCN(Cc3ccncc3)c3cc4c(cc32)COC4)n1,,CCOCC,,,,test
US20150105367A1,Cc1cc(F)c(NC(=O)NC2CCCCCC2)cc1-c1cc2cnc(NC(=O)OC(C)(C)C)cc2nc1C>>Cc1cc(F)c(NC(=O)NC2CCCCCC2)cc1-c1cc2cnc(N)cc2nc1C,,CO,,Cl,,test
US20070149579A1,Cc1nc(-c2cc(=O)oc3cc(CO)ccc23)cs1>>Cc1nc(-c2cc(=O)oc3cc(C=O)ccc23)cs1,O=[Mn]=O,ClCCl,,,,test
US04260816,CCOC(=O)c1ccc(NCCBr)cc1.Oc1cccc2c1CCCC2>>CCOC(=O)c1ccc(NCCOc2cccc3c2CCCC3)cc1,,COCCOC,,CCCCCC,[H-].[Na+],test
US05597820,CC(C)I.CCCCC1Oc2cc(C(=O)OC)ccc2NC1=O>>CCCCC1Oc2cc(C(=O)OC)ccc2N(C(C)C)C1=O,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20140142083A1,COC(=O)c1cc(Br)cc([N+](=O)[O-])c1Cl>>COC(=O)c1cc(Br)cc(N)c1Cl,[Fe],CCO,O,[Cl-].[NH4+],,test
US20010025111A1,CI.N#CCS(=O)(=O)c1ccc(Cl)cc1.S=C=Nc1cc(Cl)cc(Cl)c1>>CSC(Nc1cc(Cl)cc(Cl)c1)=C(C#N)S(=O)(=O)c1ccc(Cl)cc1,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20090291993A1,FC(F)(F)c1ccc(-c2ccc(CCl)cc2)cc1.OCc1cc(F)ccc1O>>OCc1cc(F)ccc1OCc1ccc(-c2ccc(C(F)(F)F)cc2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070054916A1,CI.Nc1ncc2cc(Br)ccc2n1>>CNc1ncc2cc(Br)ccc2n1,,CN(C)C=O,,[H-].[Na+],,test
US04616026,Fc1ccc(Br)c(F)c1.O=C(OC(=O)C(F)(F)Cl)C(F)(F)Cl>>O=C(c1ccc(F)cc1F)C(F)(F)Cl,,CCOCC,,Cl,[Mg],test
US20050209226A1,CCOC(=O)C=C1CC2CCC(C1)N2C(=O)OC(C)(C)C>>CCOC(=O)C=C1CC2CCC(C1)N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150210722A1,CC(C)c1cc(C(=O)O)n(-c2cccc(CP(C)(C)=O)c2)n1.COc1cc(Nc2cc(Oc3ccc(N)c4ccccc34)ccn2)cc(OCCN2CCOCC2)c1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(C(C)C)nn4-c4cccc(CP(C)(C)=O)c4)c4ccccc34)ccn2)cc(OCCN2CCOCC2)c1,,CC#N,CN(C)C=O,CCN(CC)CC,,test
US20090227795A1,CN(CCN(C)C(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)c1ccc(C2(C(F)(F)F)N=N2)cc1)C(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21>>CN(CCN(C)C(=O)[C@H](CCCCN)NC(=O)c1ccc(C2(C(F)(F)F)N=N2)cc1)C(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21,,CCOC(C)=O,,Cl,,test
US05106871,CC(=O)c1ccc(O)c(CC=C(C)C)c1O.CI>>COc1ccc(C(C)=O)c(O)c1CC=C(C)C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070270588A1,C=O.CCC(CC)n1ccc2c(C)nc(N(CC)c3c(C)cc(C)cc3C)nc21.CNC>>CCC(CC)n1cc(CN(C)C)c2c(C)nc(N(CC)c3c(C)cc(C)cc3C)nc21,,CO,O,,,test
US04025635,O=C(O)c1ccc(Cl)c(S(=O)(=O)c2ccccc2[N+](=O)[O-])c1>>Nc1ccccc1S(=O)(=O)c1cc(C(=O)O)ccc1Cl,,O,,CC(=O)O,Cl,test
US20150099777A1,CCc1nc2c(cc1C(=O)OC)C(=O)N(C1CCN(Cc3cc(C4CC4)c(-c4ccc(F)cc4F)c(Cl)c3OC)CC1)CC2>>CCc1nc2c(cc1C(=O)O)C(=O)N(C1CCN(Cc3cc(C4CC4)c(-c4ccc(F)cc4F)c(Cl)c3OC)CC1)CC2,,CCO,,[Na+].[OH-],,test
US05281619,CC(=O)N(C(C)=O)C1=C(C#N)C(c2cccc([N+](=O)[O-])c2)c2ccc3ccccc3c2O1>>CC(=O)NC1=C(C#N)C(c2cccc([N+](=O)[O-])c2)c2ccc3ccccc3c2O1,,ClC(Cl)Cl,,,,test
US20140114068A1,CC(C)c1ccc2c(c1)OC1(O)c3c([N+](=O)[O-])ccc(N)c3C(=O)C21O>>CC(C)c1ccc2c(c1)OC1(O)c3c(N)ccc(N)c3C(=O)C21O,[Fe],CCO,,Cl,O,test
US20020002187A1,BrBr.CC(=O)Oc1ccc(-c2c3ccccc3cc3sc(C)c(C)c23)cc1>>CC(=O)Oc1ccc(-c2c3ccccc3c(Br)c3sc(C)c(C)c23)cc1,Cl[Fe](Cl)Cl,ClCCl,,O=S([O-])O.[Na+],,test
US04266082,Cc1ccc(F)c(Oc2ccccc2)c1.O=C1CCC(=O)N1Br>>Fc1ccc(CBr)cc1Oc1ccccc1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20140045821A1,Clc1nc(Cl)c2sccc2n1>>Clc1ncc2sccc2n1,[Pd],CCO,,O=C([O-])O.[Na+],,test
US20100093757A1,COC(=O)[C@H](O)CO[C@@H](C)CO[Si](C(C)C)(C(C)C)C(C)C.Cc1cnc(N)cn1>>Cc1cnc(NC(=O)[C@@H](O)CO[C@H](C)CO[Si](C(C)C)(C(C)C)C(C)C)cn1,,Cc1ccccc1,,C[Al](C)C,,test
US20130245049A1,CCOC(=O)C(OC(C)(C)C)c1c(C)nc2cc3c(cc2c1-c1ccc(C)cc1)CCCC3>>Cc1ccc(-c2c(C(OC(C)(C)C)C(=O)O)c(C)nc3cc4c(cc23)CCCC4)cc1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20090018132A1,CC(C)(C)OC(=O)N1CCC(COC(CCO)c2cc(Cl)cc3cn(COCC[Si](C)(C)C)nc23)(c2ccc(F)cc2)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(COC(CCOS(C)(=O)=O)c2cc(Cl)cc3cn(COCC[Si](C)(C)C)nc23)(c2ccc(F)cc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20140080804A1,CCOC(=O)Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)OCC.CI>>CCOC(=O)Cc1nc(N(C)C(=O)OC(C)(C)C)sc1C(=O)OCC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080021032A1,CCC(=O)Cl.CS(=O)(=O)c1ccc([C@@H](CC2CCCC2)C(=O)Nc2cc[nH]n2)cc1Cl>>CCC(=O)n1ccc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(C)(=O)=O)c(Cl)c2)n1,,CCOC(C)=O,ClCCl,CN1CCOCC1,,test
US20090036492A1,COc1cc(O)c2c(c1C(=O)NCc1c(C)ccc3ccccc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.NOCC(=O)O>>COc1cc(O)c2c(c1C(=O)NCc1c(C)ccc3ccccc13)OC1=CC(O)=C(/C(C)=N/OCC(=O)O)C(=O)[C@]12C,,C1CCOC1,CO,O=C([O-])O.[Na+],,test
US05071844,COc1ccc(CCN2CCC[C@H]2CN2c3ccccc3CSc3ccccc32)cc1.CS(=O)(=O)O>>COc1ccc(CCN2CCC[C@H]2CN2c3ccccc3CSc3ccccc32)cc1.CS(=O)(=O)O,,ClCCl,,,,test
US20160176880A1,CC(N)(C#N)CC(F)F.O=C(Cl)OCc1ccccc1>>CC(C#N)(CC(F)F)NC(=O)OCc1ccccc1,,C1CCOC1,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20110263526A1,CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@H](CC(=O)O)OC(C)(C)O1.OC/C=C\CO>>CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@H](CC(=O)OC/C=C\CO)OC(C)(C)O1,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20160214972A1,CC(C)(C)OC(=O)Nc1ccc(C(=O)N[C@H]2C(C)(C)[C@H](Oc3ccc(C#N)c(Cl)c3)C2(C)C)cc1>>CC1(C)[C@H](NC(=O)c2ccc(N)cc2)C(C)(C)[C@H]1Oc1ccc(C#N)c(Cl)c1,,CO,,C1COCCO1,Cl,test
US20100075948A1,CC(C)(C)CC1NC(C(=O)OC(C)(C)C)C(c2cc(Br)cs2)C1(C#N)c1ccc(Cl)cc1F.O=C(O)C(F)(F)F>>CC(C)(C)CC1NC(C(=O)O)C(c2cc(Br)cs2)C1(C#N)c1ccc(Cl)cc1F.O=C(O)C(F)(F)F,,ClCCl,,,,test
US05064953,CCOC(=O)c1cc(Cl)n2ncnc2n1.[SH-]>>CCOC(=O)c1cc(S)n2ncnc2n1,,O,,Cl,,test
US20070232607A1,C[C@H](O)C(=O)N(C)C.Cc1ccc(Oc2ccc(Nc3ncnc4cccc(F)c34)cc2C)cn1>>Cc1ccc(Oc2ccc(Nc3ncnc4cccc(O[C@@H](C)C(=O)N(C)C)c34)cc2C)cn1,,C1CCOC1,,[H-].[Na+],,test
US20030134854A1,COc1ccc(N2CCOCC2)c2sc(NC(=O)c3ccc(Cl)nc3)nc12.C[C@H]1CNC[C@@H](C)O1>>COc1ccc(N2CCOCC2)c2sc(NC(=O)c3ccc(N4C[C@H](C)O[C@H](C)C4)nc3)nc12,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160009744A1,CC(C)(C)[Si](C)(C)OCc1coc(C(O)c2cncnc2Cl)c1>>CC(C)(C)[Si](C)(C)OCc1coc(C(=O)c2cncnc2Cl)c1,O=[Mn]=O,ClCCl,,,,test
US20140024650A1,C=Cc1cnn(-c2ccc(OC)cc2)c1.COc1ccc(-n2cc(Br)cn2)cc1>>CCc1cnn(-c2ccc(OC)cc2)c1,[Pd],C1CCOC1,CCO,,,test
US03968235,CC(=CCCl)CCOC(C)C.Oc1ccc2c(c1)OCO2>>CC(=CCOc1ccc2c(c1)OCO2)CCOC(C)C,,COCCOC,,[K+].[OH-],,test
US20130045169A1,CC(C)(C)OC(=O)NC(c1ccccc1)c1cccc(OCCCCCC2OCCO2)c1>>COC(CCCCCOc1cccc(C(N)c2ccccc2)c1)OC,,CO,,C1COCCO1,Cl,test
US20020130937A1,Cl.Nc1ccccn1.O=C(OO)c1cccc(Cl)c1>>Cl.Nc1cccc[n+]1[O-],,CC(C)=O,,CCOCC,,test
US20040143024A1,OC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO>>OC[C@@H](O)[C@H](O)[C@H](O)[C@H](O)CO,[Pt],,,,,test
US20090318690A1,C=CCc1cc(O)cc(C(C)=NO)c1O.CC(=O)OC(C)=O>>C=CCc1cc(OC(C)=O)cc2c(C)noc12,,CN(C)C=O,,CC(=O)[O-].[Na+],,test
US20100317739A1,CN(C)c1cccc2c(S(=O)(=O)NCCCCCC(=O)O)cccc12.NOCc1ccccc1>>CC(CCCC(=O)NOCc1ccccc1)NS(=O)(=O)c1cccc2c(N(C)C)cccc12,CN(C)c1ccncc1,C1CCOC1,O,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20110207709A1,Cc1ccccc1-c1ccc(C=O)c(OC2CN(C(=O)OC(C)(C)C)C2)c1.O=C(OO)c1cccc(Cl)c1>>Cc1ccccc1-c1ccc(O)c(OC2CN(C(=O)OC(C)(C)C)C2)c1,,ClCCl,,,,test
US20060183783A1,CS(=O)(=O)Cl.Cc1ccc(NC(=O)Nc2nc(CCN)cs2)c(C(=O)C2CCCC2)c1>>Cc1ccc(NC(=O)Nc2nc(CCNS(C)(=O)=O)cs2)c(C(=O)C2CCCC2)c1,,ClCCl,,c1ccncc1,,test
US08394820B2,CCOC(=O)C(=O)CBr.Nc1cc(NC(=O)c2cc3cc(C(F)(F)F)cnc3n2Cc2cccc(F)c2)ccn1>>CCOC(=O)c1cn2ccc(NC(=O)c3cc4cc(C(F)(F)F)cnc4n3Cc3cccc(F)c3)cc2n1,,CC#N,,,,test
US20150291563A1,COC(=O)C(=O)C=Cc1ccc(Br)cc1.NNc1ccc(F)cc1F>>COC(=O)C1=NN(c2ccc(F)cc2F)C(c2ccc(Br)cc2)C1,,CC(=O)O,,Cl,,test
US20150181868A1,CC(=O)OCBr.CCCO[C@H]1COC[C@H](NC(=O)c2nccc(OC)c2O)C(=O)O[C@@H](C)[C@@H]1CCC(C)C>>CCCO[C@H]1COC[C@H](NC(=O)c2nccc(OC)c2OCOC(C)=O)C(=O)O[C@@H](C)[C@@H]1CCC(C)C,,CC(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20050288480A1,CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4CC(OC(=O)C(Cc5ccc([N+](=O)[O-])cc5)Cc5ccc([N+](=O)[O-])cc5)CC[C@]4(C)[C@H]3CC[C@]12C>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4CC(OC(=O)C(Cc5ccc(N)cc5)Cc5ccc(N)cc5)CC[C@]4(C)[C@H]3CC[C@]12C,[Zn],CO,O,[Cl-].[NH4+],,test
US20110118314A1,CC(=O)OC(C)=O.COc1cc(F)c(F)cc1-c1ccc(OCC2CCCN(C(=O)[C@@H](CC(=O)OCc3ccccc3)NC(=O)OC(C)(C)C)C2)cc1>>COc1cc(F)c(F)cc1-c1ccc(OCC2CCCN(C(=O)[C@@H](CC(=O)OCc3ccccc3)NC(C)=O)C2)cc1,,C1COCCO1,ClCCl,CCN(CC)CC,Cl,test
US06228868B1,FC(F)(F)Cn1ccc2cc(OCc3ccccc3)ccc21>>Oc1ccc2c(ccn2CC(F)(F)F)c1,,ClCCl,,BrB(Br)Br,O,test
US04438271,CC(=O)c1c(F)cccc1F>>CC(O)c1c(F)cccc1F,,CC(C)O,O,Cl,[Na+].[OH-],test
US20120214784A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1cn(-c2c(F)cccc2CNC2CC2)nc1C>>CCOC(=O)c1cn(-c2c(F)cccc2CN(C(=O)OC(C)(C)C)C2CC2)nc1C,,ClCCl,,CCN(CC)CC,O,test
US20060241173A1,N#Cc1ccc(N(Cc2ccc(Br)c(OC3CCCCO3)c2)n2cnnc2)cc1>>N#Cc1ccc(N(Cc2ccc(Br)c(O)c2)n2cnnc2)cc1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20150284362A1,CC(C)(C)OC(=O)N1CCCCC1=O.O=S(=O)(c1ccccc1)N(F)S(=O)(=O)c1ccccc1>>CC(C)(C)OC(=O)N1CCCC(F)C1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20040121965A1,COc1cccc(C=O)c1.O=C1CNC(=O)N1>>COc1cccc(/C=C2/NC(=O)NC2=O)c1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20100234351A1,C=CS(C)(=O)=O.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1CC1>>CC(C)(C)OC(=O)N(CCS(C)(=O)=O)C1CC1,,CO,,,,test
US20100022468A1,CCOC(=O)[C@H](C)N.O=P(Cl)(Cl)OP(=O)([O-])Oc1ccc(Cl)cc1>>CCOC(=O)[C@H](C)NP(=O)(Cl)Oc1ccc(Cl)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US06225320B1,BrBr.COc1cnc(C(F)(F)F)cc1[Sn](C)(C)C>>COc1cnc(C(F)(F)F)cc1Br,,ClCCl,,O=S([O-])[O-].[Na+].[Na+],,test
US05238939,CCC(=O)CCCl.CN1CCNCC1>>CCC(=O)CCN1CCN(C)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120108583A1,CS(=O)(=O)O.Cc1cccc(Cl)c1Nc1nc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3F)c3c(c2[nH]1)CC(C)(C)O3>>CS(=O)(=O)O.Cc1cccc(Cl)c1Nc1nc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3F)c3c(c2[nH]1)CC(C)(C)O3,,CC(C)=O,,,,test
US20160068531A1,CC(=O)OC(C)=O.O=C1N(Cc2cc3cc(Cl)ccc3n2CCN2CCNCC2)c2cnccc2C12CC2>>CC(=O)N1CCN(CCn2c(CN3C(=O)C4(CC4)c4ccncc43)cc3cc(Cl)ccc32)CC1,,ClCCl,,CCN(CC)CC,,test
US20100298377A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nn(C(=O)OC(C)(C)C)c2ccc([N+](=O)[O-])cc12>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nn(C(=O)OC(C)(C)C)c2ccc(N)cc12,[Pd],CCO,,,,test
US20120010135A1,OC1c2ccccc2CC12CCN(Cc1ccccc1)CC2>>c1ccc(CN2CCC3(CC2)Cc2ccccc2C3)cc1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20060241147A1,C=O.CC#N.Nc1ccc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)nc1>>CN(C)c1ccc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)nc1,,CC#N,,CC(=O)O,[BH3-]C#N.[Na+],test
US20080119488A1,CC(C)(C)OC(=O)n1ccc2ccc(B3OC(C)(C)C(C)(C)O3)cc21.Cc1ccc(Cn2c(-c3cccc(Br)c3)cc(C(F)(F)F)c(C#N)c2=O)c(C)c1>>Cc1ccc(Cn2c(-c3cccc(-c4ccc5ccn(C(=O)OC(C)(C)C)c5c4)c3)cc(C(F)(F)F)c(C#N)c2=O)c(C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,N#N,O=C([O-])[O-].[K+].[K+],test
US20070105904A1,C#CCOCc1ccc(CCl)cc1.Nc1ncccc1-c1cn[nH]c1>>C#CCOCc1ccc(Cn2cc(-c3cccnc3N)cn2)cc1,,CN(C)C=O,O,C1CCOC1,[H-].[Na+],test
US06414005B1,CCI.Cc1c(NC(N)=S)ccc(-n2cccn2)c1CNC(=O)OC(C)(C)C>>CCSC(=N)Nc1ccc(-n2cccn2)c(CNC(=O)OC(C)(C)C)c1C,,CC#N,,,,test
US20130197009A1,CC1(C)CN(Cc2ccccc2)CCN1c1ccc(C#N)c(Cl)c1>>CC1(C)CNCCN1c1ccc(C#N)c(Cl)c1,,ClCCCl,,CC(Cl)OC(=O)Cl,,test
US05484795,COc1ccc(C2=C(C(O)c3ccc(OCCN4CCCC4)cc3)c3ccccc3CC2)cc1.Cl>>COc1ccc(-c2ccc3ccccc3c2Cc2ccc(OCCN3CCCC3)cc2)cc1.Cl,,CO,,,,test
US20080207728A1,COC(=O)c1cc(Br)cc2c1OCCCC2>>O=C(O)c1cc(Br)cc2c1OCCCC2,,CO,,[K+].[OH-],,test
US05070207,C#CC(C)(C)CCOc1ccc(Cl)cc1.CCOC(=O)C(F)(F)F>>CC(C)(C#CC(=O)C(F)(F)F)CCOc1ccc(Cl)cc1,,C1CCOC1,,[Li]CCCC,,test
US20140031342A1,CC(C)(C)OC(=O)N1CCC(CCOc2ccc(OC(F)(F)F)cc2)CC1>>FC(F)(F)Oc1ccc(OCCC2CCNCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060040888A1,CC(C)(C)OC(=O)N1CCC(CO)CC1.Cc1ccccc1S(=O)(=O)Cl>>Cc1ccc(S(=O)(=O)OCC2CCN(C(=O)OC(C)(C)C)CC2)cc1,,ClC(Cl)Cl,,c1ccncc1,,test
US20080021043A1,COC(=O)Cc1ccnc(-c2ccc(C(F)(F)F)cc2)c1.ClC/C=C\CCl>>COC(=O)C1(c2ccnc(-c3ccc(C(F)(F)F)cc3)c2)CC=CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20110166163A1,CCCC[Sn](CCCC)(CCCC)c1ccc(CC)cn1.C[C@H](CCCCC(=O)OC(C)(C)C)Oc1ncnc2oc(-c3ccccc3)c(Br)c12>>CCc1ccc(-c2c(-c3ccccc3)oc3ncnc(O[C@H](C)CCCCC(=O)OC(C)(C)C)c23)nc1,,Cc1ccccc1,,,,test
US20070015207A1,Nc1ccc2c(c1)CCC2.O=[N+]([O-])c1cnc(Cl)nc1Cl>>O=[N+]([O-])c1cnc(Cl)nc1Nc1ccc2c(c1)CCC2,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US05886178,Cc1cccc(C(=O)O)c1Cl.O=C(Cl)C(=O)Cl>>Cc1cccc(C(=O)Cl)c1Cl,CN(C)C=O,CCOC(C)=O,,,,test
US20020151715A1,CC(=O)O.CCOC(=O)C[N+](=O)[O-].CCOC(OCC)OCC.Nc1ccc(F)c(Br)c1>>OCc1cn(-c2ccc(F)c(Br)c2)cn1,[Fe],,,,,test
US20040127524A1,CC#CCOc1ccc(S(=O)(=O)Oc2c(C)cccc2C(=O)OC)cc1>>CC#CCOc1ccc(S(=O)(=O)Oc2c(C)cccc2C(=O)O)cc1,,CCOC(C)=O,,[I-].[Li+],,test
US20160200725A1,CC(C)(C)OC(=O)N1CC(=O)C1.COc1cc(OC)c(Cl)c(-c2cc3cnc(SC)nc3n(CCN)c2=O)c1Cl>>COc1cc(OC)c(Cl)c(-c2cc3cnc(SC)nc3n(CCNC3CN(C(=O)OC(C)(C)C)C3)c2=O)c1Cl,,ClCCl,,[BH3-]C#N.[Na+],,test
US20100137307A1,CC1(C)Nc2ccc(Br)c(CO)c2NC1=O.CI>>CN1C(=O)C(C)(C)Nc2ccc(Br)c(CO)c21,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20060111427A1,Fc1cc2cc(-c3ccccc3)[nH]c2cc1Cl.O=[N+]([O-])c1ccc(SSc2ccc([N+](=O)[O-])cc2)cc1>>O=[N+]([O-])c1ccc(Sc2c(-c3ccccc3)[nH]c3cc(Cl)c(F)cc23)cc1,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20150232452A1,CCn1cc(-c2cccc(N)c2)c(-c2ccncc2)n1.O=C=Nc1ccccc1F>>CCn1cc(-c2cccc(NC(=O)Nc3ccccc3F)c2)c(-c2ccncc2)n1,,ClCCl,,,,test
US06087364,CN1C(=O)c2ccccc2C1CCO.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)CCC2c3ccccc3C(=O)N2C)cc1,,ClCCl,,,,test
US20140213581A1,COC(=O)c1ncc(OC)nc1C>>COc1cnc(C(=O)O)c(C)n1,,CO,,[Na+].[OH-],,test
US04956382,CNCCc1ccc([N+](=O)[O-])cc1.O=[N+]([O-])c1ccc2oc(CBr)cc2c1>>CN(CCc1ccc([N+](=O)[O-])cc1)Cc1cc2cc([N+](=O)[O-])ccc2o1,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US20070037851A1,CC(C)(C)OC(=O)N1CCC(F)(CN)CC1.O=C(N=C=S)OCC1c2ccccc2-c2ccccc21>>CC(C)(C)OC(=O)N1CCC(F)(CNC(=S)NC(=O)OCC2c3ccccc3-c3ccccc32)CC1,,C1CCOC1,,,,test
US20050085483A1,CC(C)N1CC2N(C(=O)C(N)CN2S(=O)(=O)c2ccc(Cl)cc2Cl)C(Cc2ccc(Cl)cc2)C1=O.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(C)N1CC2N(C(=O)C(NC(=O)C(F)(F)F)CN2S(=O)(=O)c2ccc(Cl)cc2Cl)C(Cc2ccc(Cl)cc2)C1=O,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20040058820A1,BrC1CCC1.CC#N.CC(=O)Cc1cccc(C#N)c1>>CC(=O)C(CC1CCC1)c1cccc(C#N)c1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040142850A1,CCOC(=O)N(Cc1ccccc1Cl)c1c(N)cc(N)cc1C(F)(F)F>>Nc1cc(C(F)(F)F)c2c(c1)[nH]c(=O)n2Cc1ccccc1Cl,,CCO,,[H-].[Na+],,test
US06124277,CCN(CC(=O)OC(C)(C)C)C(=O)[C@H]1CCCCN1C(=O)OCc1ccccc1>>CCN(CC(=O)O)C(=O)[C@H]1CCCCN1C(=O)OCc1ccccc1,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US05350538,C=CCCCCCCOc1ccc(C(=O)OC)cc1>>C=CCCCCCCOc1ccc(C(=O)O)cc1,,CO,O,Cl,[K+].[OH-],test
US05302720,Nc1ccc(F)cc1-c1ccccc1.S=C(Cl)Cl>>Fc1ccc(N=C=S)c(-c2ccccc2)c1,,C1COCCO1,O,,,test
US20090176769A1,OCc1cccc(F)c1NCCN1CCCCC1>>O=Cc1cccc(F)c1NCCN1CCCCC1,O=[Mn]=O,Cc1ccccc1,,,,test
US05180723,CC#N.COc1ccc(C(=O)c2ccc(OC)cc2)cc1>>COc1ccc(C(O)(CC#N)c2ccc(OC)cc2)cc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20100173933A1,BrCCCCCCCCOC1CCCCO1.CCCCC.CS(C)=O>>C#CCCCCCCCCCO,,CS(C)=O,,,,test
US04323707,COc1ccc([Mg]Br)cc1.COc1ccc2c(c1)CCC(=O)C2C(=O)c1ccc(OCc2ccccc2)cc1>>COc1ccc(C2=C(C(=O)c3ccc(OCc4ccccc4)cc3)c3ccc(OC)cc3CC2)cc1,,C1CCOC1,,[Cl-].[NH4+],,test
US20100331326A1,Cc1ccncc1N1CCNC1=O.O=Cc1cc(Br)ccc1F>>Cc1ccncc1N1CCN(c2ccc(F)c(C=O)c2)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20120122930A1,CCOC(=O)c1cc([N+](=O)[O-])c(NCc2ccccc2)cc1OCCN(C)C>>CCOC(=O)c1cc(N)c(N)cc1OCCN(C)C,[Pd],C1CCOC1,CO,,,test
US20100069381A1,CSc1ccc(CO)cc1C(F)(F)F.O=S(Cl)Cl>>CSc1ccc(CCl)cc1C(F)(F)F,,Cc1ccccc1,,,,test
US05382379,OC1(c2cc(F)c(C(F)(F)F)c(F)c2)CCC2(CC1)OCCO2>>Fc1cc(C2=CCC3(CC2)OCCO3)cc(F)c1C(F)(F)F,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20110110889A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=Cc1c[nH]c2ncccc12>>Cc1ccc(S(=O)(=O)n2cc(C=O)c3cccnc32)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20140038981A1,C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(C)CC4)cc3)nc3c2ccn3CO)c1>>C=C(C(N)=O)c1cccc(Oc2nc(Nc3ccc(N4CCN(C)CC4)cc3)nc3[nH]ccc23)c1,,CO,,N,,test
US20040082781A1,CCCN(C(=O)OC(C)(C)C)c1c(CC)nc2c(-c3ccc(Cl)cc3Cl)nccn12>>CCCNc1c(CC)nc2c(-c3ccc(Cl)cc3Cl)nccn12,,CCOC(C)=O,,Cl,[Na+].[OH-],test
US20160176864A1,Cn1nnc(CO)c1-c1cnc2c3ccc(C(C)(C)O)cc3n([C@H](c3ccccc3)C3CCOCC3)c2c1>>Cn1nnc(C=O)c1-c1cnc2c3ccc(C(C)(C)O)cc3n([C@H](c3ccccc3)C3CCOCC3)c2c1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20040067964A1,CCOC(=O)c1ccc(C#C[Si](C)(C)C)o1.CS(=O)(=O)c1ccc(NS(=O)(=O)c2ccccc2)c(I)c1>>CCOC(=O)c1ccc(-c2cc3cc(S(C)(=O)=O)ccc3[nH]2)o1,,CN(C)C=O,,O,CC(=O)[O-].[K+],test
US20080293718A1,Brc1cccc(C#Cc2ccc3c(c2)CCO3)c1.CS(C)=O.O>>O=C(C(=O)c1ccc2c(c1)CCO2)c1cccc(Br)c1,Cl[Pd]Cl,,,,,test
US20150080393A1,C=Cc1ccc(-n2ccc(C)n2)c([C@@H](Oc2cc(N3CCC4(CC3)CN[C@H](C(=O)OCC)C4)nc(N)n2)C(F)(F)F)c1>>CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4cc(CC)ccc4-n4ccc(C)n4)C(F)(F)F)nc(N)n3)CC2)CN1,[Pd],CO,,,,test
US20040186091A1,CCN(C(C)C)C(C)C.CN(C)S(=O)(=O)Cl.Clc1ccc2c(c1)CNCc1nnc(C3CCN(c4ncccn4)CC3)n1-2>>CN(C)S(=O)(=O)N1Cc2cc(Cl)ccc2-n2c(nnc2C2CCN(c3ncccn3)CC2)C1.N,,ClCCl,,,,test
US05082976,O=O.O=[N+]([O-])c1ccccc1C=CN1CCOCC1>>O=Cc1ccccc1[N+](=O)[O-],Cl[Cu],CS(C)=O,,,,test
US20010049374A1,COc1cc2c(c(OC)c1)C(=O)CCC2>>COc1cc(O)c2c(c1)CCCC2=O,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20140364431A1,COc1cc(C(C)=O)c([N+](=O)[O-])cc1OCCCCl>>COc1cc(C(C)=O)c(N)cc1OCCCCl,[Fe],CCO,,Cl,,test
US20120329780A1,CC(=O)N1CCN(c2ccc(N)cc2)CC1.COC(=O)c1cccc(-c2nc(Cl)c3nn(Cc4ccc(OC)cc4)cc3n2)c1>>COC(=O)c1cccc(-c2nc(Nc3ccc(N4CCN(C(C)=O)CC4)cc3)c3[nH]ncc3n2)c1,C1COCCO1,CO,,Cl,,test
US20110034433A1,CC1(C)OI(C(F)(F)F)c2ccccc21.CC1=C(C#N)[C@@H](c2ccc(C#N)cc2S)N(C)C(=O)N1c1cccc(C(F)(F)F)c1>>CC1=C(C#N)[C@@H](c2ccc(C#N)cc2SC(F)(F)F)N(C)C(=O)N1c1cccc(C(F)(F)F)c1,,ClCCl,,,,test
US20160176857A1,CC1CCN(C2CCN(c3ccc(Nc4n[nH]c(N)c4C(N)=O)cc3)CC2)CC1.Cc1cc(C=O)cc(C)c1O>>Cc1cc(CNc2[nH]nc(Nc3ccc(N4CCC(N5CCC(C)CC5)CC4)cc3)c2C(N)=O)cc(C)c1O,C1CCNCC1,CCO,,O,[BH4-].[Na+],test
US05693310,CCOC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O.Nc1ccccc1>>O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CCN(CC(=O)O)CC(=O)Nc1ccccc1,,CO,,,,test
US20040248872A1,CC(CCCCOC(=O)c1ccc2[nH]ccc2c1)=C(F)F.CI>>CC(CCCCOC(=O)c1ccc2c(ccn2C)c1)=C(F)F,,O,,CN(C)C=O,[H-].[Na+],test
US20160244437A1,COCCOCCOCCN.Cc1cc(C(=O)O)ccc1-c1cccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)c1>>COCCOCCOCCNC(=O)c1ccc(-c2cccc(C[C@H](NC(=O)[C@@H]3CC[C@@H](CNC(=O)OC(C)(C)C)CC3)C(=O)Nc3ccc(-c4nnn[nH]4)cc3)c2)c(C)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05514811,CC(C)c1nc(CO)c(CO)[nH]1.O=C1CCC(=O)N1Cl>>CC(C)c1nc(Cl)c(CO)[nH]1,,CCO,,,,test
US20090082597A1,CNCCC(O)c1ccccc1.O=C(O)[C@@H](O)c1ccccc1>>CNCC[C@@H](O)c1ccccc1.O=C(O)[C@@H](O)c1ccccc1,,CCOC(C)=O,,,,test
US06613766B1,CCOC(=O)c1cc(C)on1.NN>>Cc1cc(C(=O)NN)no1,,CO,,O,,test
US20090143375A1,CC1(C)C(=O)Nc2cc([N+](=O)[O-])ccc21.ClCCCN1CCOCC1>>CC1(C)C(=O)N(CCCN2CCOCC2)c2cc([N+](=O)[O-])ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20130190289A1,COC(=O)c1sc(-c2ccc(Oc3ccccc3)cc2)cc1N(CC(=O)N1CCOCC1)C(=O)c1ccc(Cl)cc1Cl>>O=C(O)c1sc(-c2ccc(Oc3ccccc3)cc2)cc1N(CC(=O)N1CCOCC1)C(=O)c1ccc(Cl)cc1Cl,,C1CCOC1,O,Cl,[Li]O,test
US20110312936A1,CCN(C(=O)OCc1ccccc1)C1CCC2(CC1)OCCO2>>CCN(C(=O)OCc1ccccc1)C1CCC(=O)CC1,,CC#N,,Cl,,test
US20070275962A1,CCOC(=O)c1c(N)sc2c1CCOC2.CS(=O)(=O)Cl>>CCOC(=O)c1c(NS(C)(=O)=O)sc2c1CCOC2,,c1ccccc1,,CCN(CC)CC,,test
US20120238539A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(N2CCNCC2)c(Cl)cc1Br>>CC(C)(C)OC(=O)N1CCN(c2cc(N)c(Br)cc2Cl)CC1,,ClCCl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20080280876A1,CC(C)Oc1ccc(C#N)cc1Cl.NO>>CC(C)Oc1ccc(C(=N)NO)cc1Cl,,CCO,,,,test
US20030195201A1,CC(C)(C)c1ccc(/C=C/C(=O)Nc2ccc3cn[nH]c3c2)cc1.CN=C=O>>CNC(=O)n1ncc2ccc(NC(=O)/C=C/c3ccc(C(C)(C)C)cc3)cc21,,CCOC(C)=O,,C1CCOC1,,test
US20110195948A1,Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3C(F)F)nc12.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3C(F)F)nc12)N1CC[C@@H](O)C1,,ClCCl,,,,test
US04337247,CCOC(=O)CNC(=O)[C@@H](CCSC)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C>>CSCC[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)NCC(=O)O,,CO,,Cl,[Na+].[OH-],test
US03954983,Br.CC1CCC(=O)c2ccccc21>>CC1CC(Br)C(=O)c2ccccc21,,CCOC(C)=O,,ClC(Cl)Cl,,test
US08003663B2,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CN.O=C(Cl)c1ccc(CCCCOCCCCBr)cc1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1ccc(CCCCOCCCCBr)cc1,,ClCCl,,CCN(CC)CC,O,test
US20090209607A1,Cn1ncc(Br)c1-c1cc(C(=O)O)sc1Cl.N[C@@H](CC1CCCCC1)CN1C(=O)c2ccccc2C1=O>>Cn1ncc(Br)c1-c1cc(C(=O)N[C@@H](CC2CCCCC2)CN2C(=O)c3ccccc3C2=O)sc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US07064102B2,CC1(C)CCCC(C(C)(C)O)C1.O=C(CCl)OC(=O)CCl>>CC1(C)CCCC(C(C)(C)OC(=O)CCl)C1,,c1ccncc1,,O,,test
US20010000038A1,COC(=O)C(C)(C)c1ccc(C(=O)CCCCl)cc1.OC(c1ccccc1)(c1ccccc1)C1CCNCC1>>COC(=O)C(C)(C)c1ccc(C(=O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1.Cl,,Cc1ccccc1,,,,test
US20150232444A1,Cc1cc(C)c(S(=O)(=O)N2CCC(=O)CC2)c(C)c1.N#CCCC1CCNCC1>>Cc1cc(C)c(S(=O)(=O)N2CCC(N3CCC(CCC#N)CC3)CC2)c(C)c1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US06407243B1,COc1ccc(-c2oc3cc(OC)ccc3c2C(=O)c2ccc(OCCN(C)C)cc2)cc1>>COc1ccc(-c2oc3cc(OC)ccc3c2C(O)c2ccc(OCCN(C)C)cc2)cc1,,CO,,,,test
US20080188499A1,NCCN.O=[N+]([O-])c1ccc(C=Cc2nc(Cl)c3ccccc3n2)o1>>NCCNc1nc(C=Cc2ccc([N+](=O)[O-])o2)nc2ccccc12,,CN(C)C=O,Cc1ccccc1,,,test
US04550203,CC(=O)NC#N.CCCCCCCBr>>CCCCCCCN(C#N)C(C)=O,,CN(C)C=O,,[Na],,test
US20080318929A1,CC(C)(C)OC(=O)NCC(=O)Nc1cccc(CN)c1.O=[N+]([O-])c1cnc(Cl)nc1NC[C@@H]1CC[C@@H](CO)CC1>>CC(C)(C)OC(=O)NCC(=O)Nc1cccc(CNc2ncc([N+](=O)[O-])c(NC[C@@H]3CC[C@@H](CO)CC3)n2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20100249123A1,CC(=O)Cl.CCc1cc(NC(=O)c2ccc(OC)c(OC)c2)ccc1C(C)(C)CN>>CCc1cc(NC(=O)c2ccc(OC)c(OC)c2)ccc1C(C)(C)CNC(C)=O,,ClCCl,,CCN(CC)CC,,test
US04631147,C=CCBr.CC1(C)CCCC(C)(C)C1=O>>C=CCC1(O)C(C)(C)CCCC1(C)C,,CCOCC,O,Cl,[Mg],test
US20050014941A1,CCOC(=O)CS.N#CCNC(=O)[C@@H]1CCCC[C@H]1CS(=O)(=O)c1ccc(F)cc1>>CCOC(=O)CSc1ccc(S(=O)(=O)C[C@@H]2CCCC[C@H]2C(=O)NCC#N)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050239786A1,NO.O=C(c1ccccc1Cl)c1c(CCO)noc1-c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1-c1ccccc1>>OCCc1noc(-c2nnn(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)c2-c2ccccc2)c1C(=NO)c1ccccc1Cl,,c1ccncc1,,Cl,,test
US20090023703A1,CCOC(=O)c1cc2ncccc2[nH]1>>O=C(O)c1cc2ncccc2[nH]1,,[Na+],[OH-],CC(=O)O,,test
US20080182854A1,CC(C)(C)OC(=O)/C=C/c1cccc(CO)n1>>CC(C)(C)OC(=O)CCc1cccc(CO)n1,O=[Pt]=O,CCO,,,,test
US20090170907A1,ClCc1ncc(COCc2ccccc2)o1.N#Cc1ccc(NCC(F)(F)F)cc1C(F)(F)F>>N#Cc1ccc(N(Cc2ncc(COCc3ccccc3)o2)CC(F)(F)F)cc1C(F)(F)F,,CN(C)C=O,,,,test
US20140005146A1,CCOC(=O)CN.COC=O>>CCOC(=O)CNC=O,,CCN(CC)CC,,Cl,,test
US05128351,CCCCCCCCCCCCCCOc1cccc(CC(=O)Nc2cccc(CBr)c2)c1.Cc1cncs1>>CCCCCCCCCCCCCCOc1cccc(CC(=O)Nc2cccc(C[n+]3csc(C)c3)c2)c1.[Br-],,Cc1ccccc1,,,,test
US20080015199A1,COC(=O)N=C(SC)C(=Nc1ccc(-c2noc(C)n2)cc1)c1cc(OC)c(OC)c(C(C)O)c1.NNc1ncccn1>>COc1cc(C(Nc2ccc(-c3noc(C)n3)cc2)C2NC(=O)N(c3ncccn3)N2)cc(C(C)O)c1OC,,CN(C)C=O,,CCN(CC)CC,,test
US20080234276A1,CC(C)(C)OC(=O)N1CCC(COc2ccc3nnc(N)nc3c2)CC1.Cl>>Cl.Nc1nnc2ccc(OCC3CCNCC3)cc2n1,,C1COCCO1,Cl,ClCCl,,test
US20160052888A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=C1N[C@@]2(CC[C@H](c3ccc4c(c3)CCC(OCCO)C4)C2)CO1>>Cc1ccc(S(=O)(=O)OCCOC2CCc3cc([C@H]4CC[C@]5(COC(=O)N5)C4)ccc3C2)cc1,,CCOC(C)=O,c1ccncc1,,,test
US20100120761A1,NCC(F)(F)F.Nc1ccnc(Cl)c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(NCC(F)(F)F)Nc1ccnc(Cl)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20160137636A1,COc1cc(-c2cccc(Cl)c2)c(F)cc1B(O)O.Clc1ncnc2cc(SCc3ccccc3)ccc12>>COc1cc(-c2cccc(Cl)c2)c(F)cc1-c1ncnc2cc(SCc3ccccc3)ccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20040176389A1,c1c(COC2CCCCO2)noc1CN1CCOCC1>>OCc1cc(CN2CCOCC2)on1,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080287517A1,Cc1c(C(=O)O)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(OCCCF)cc1.O=C(Cl)C(=O)Cl>>Cc1c(C(=O)Cl)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(OCCCF)cc1,,ClCCl,,CN(C)C=O,,test
US20060025414A1,CN(C)Cc1ccc(C(=O)NN)cc1.CN=C(SC)N1CCCCC1c1nnn(-c2cccc(Cl)c2)n1>>CN(C)Cc1ccc(-c2nnc(N3CCCCC3c3nnn(-c4cccc(Cl)c4)n3)n2C)cc1,,CCO,CCOC(C)=O,,,test
US05807859,Cn1cncc1C=c1c2ccccc2c2[nH]c(=O)c3nccn3c12>>Cn1cncc1CC1c2ccccc2-c2[nH]c(=O)c3nccn3c21,[Pd],O,,Cl,[H][H],test
US20050124683A1,BrCC1CC1.O=C(O)c1cccc2[nH]ccc12>>OCc1cccc(OCC2CC2)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20090062273A1,Cc1ccc(F)c(N=C=O)c1.Cn1ncc2c(-c3ccc(N)cc3)cncc21>>Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cncc4c3cnn4C)cc2)c1,,ClCCl,,,,test
US20090270450A1,CCOc1cc([N+](=O)[O-])ccc1-c1ccncc1.CI>>CCOc1cc([N+](=O)[O-])ccc1-c1cc[n+](C)cc1.[I-],,CC#N,CCOCC,,,test
US04044021,CN1C(=N)N(c2ccccc2)CC1=O.Cl>>CN1C(=N)N(c2ccccc2)CC1=O.Cl,,CCOCC,,CCO,,test
US20160198713A1,FC(F)c1cc(C(F)F)[nH]n1.N#CC1CCN(C(=O)C(Br)C(=O)OCc2ccccc2)CC1>>N#CC1CCN(C(=O)C(C(=O)OCc2ccccc2)n2nc(C(F)F)cc2C(F)F)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150005278A1,COC(=O)[C@@H](C)Oc1ncccc1[N+](=O)[O-]>>C[C@@H](Oc1ncccc1[N+](=O)[O-])C(=O)O,,CO,,Cl,[Na+].[OH-],test
US20150141406A1,CC1(C)OB(c2ccc(N3CCOCC3)cc2)OC1(C)C.COc1nccc2c1c(OS(=O)(=O)C(F)(F)F)nn2-c1c(F)cccc1F>>COc1nccc2c1c(-c1ccc(N3CCOCC3)cc1)nn2-c1c(F)cccc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US06222048B1,C=CCC(C)(C)C=O.Cl[Mg]Cc1ccccc1>>C=CCC(C)(C)C(O)Cc1ccccc1,,CCOCC,,,,test
US20090312338A1,O=C(O)C1CCNCC1.O=C(OCc1ccccc1)ON1C(=O)CCC1=O>>O=C(O)C1CCN(C(=O)OCc2ccccc2)CC1,,CC#N,O,O=C([O-])[O-].[Na+].[Na+],,test
US20040259904A1,CC(=O)Cl.Cc1ccc(Br)cc1N>>CC(=O)Nc1cc(Br)ccc1C,,c1ccncc1,,,,test
US20120196864A1,Cc1cc(C=O)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F.O=C1CSC(=O)N1>>Cc1cc(/C=C2\SC(=O)NC2=O)ccc1OCc1ccc(C(F)(F)F)cc1C(F)(F)F,,CCO,,C1CCNCC1,,test
US20040242641A1,CC(C)(C)OC(=O)N1C[C@H]2CN(c3cnc(Cl)c(Cl)c3)C[C@H]21.Cc1ccc(S(=O)(=O)O)cc1>>Cc1ccc(S(=O)(=O)O)cc1.Clc1cc(N2C[C@@H]3CN[C@@H]3C2)cnc1Cl,,CCOC(C)=O,,O,,test
US20090221555A1,O=C(O)c1cc(F)cc(F)c1[N+](=O)[O-]>>Nc1c(F)cc(F)cc1C(=O)O,[Pd],CO,,,,test
US20010044452A1,COc1ccc(C(=O)Cl)cc1.Cn1cccc1>>COc1ccc(C(=O)c2cccn2C)cc1,,Cc1ccccc1,,,,test
US20110300174A1,CN1CCC[C@H]1c1cncc(OCCNC(=O)OC(C)(C)C)c1>>CN1CCC[C@H]1c1cncc(OCCN)c1,,O=C(O)C(F)(F)F,,ClCCl,,test
US20080161294A1,C[C@H](CO)N=Cc1ccccc1NC(=O)c1ccc(N2CCCC2)cc1Cl>>C[C@H](CO)NCc1ccccc1NC(=O)c1ccc(N2CCCC2)cc1Cl,,CCO,,[BH4-].[Na+],,test
US20050282819A1,CC(=O)Cl.NC1CCc2ccc(CCN3CCN(c4nsc5ccccc45)CC3)cc21>>CC(=O)NC1CCc2ccc(CCN3CCN(c4nsc5ccccc45)CC3)cc21,,C1CCOC1,,CCN(CC)CC,,test
US06187780B1,BrBr.COc1ccc(Cn2c(N)cc(=O)[nH]c2=O)cc1>>COc1ccc(Cn2c(N)c(Br)c(=O)[nH]c2=O)cc1,,CO,,O=C([O-])O.[Na+],,test
US20100210620A1,CC(C)(C1CCNCC1)S(=O)(=O)c1cccc(C(F)(F)F)c1.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1Br>>CC(C)(C1CCN(S(=O)(=O)c2ccc(C(F)(F)F)cc2Br)CC1)S(=O)(=O)c1cccc(C(F)(F)F)c1,,CCOC(C)=O,,ClCCl,,test
US20160222014A1,C[C@H]1CN(C(=O)OC(C)(C)C)CCN1.O=Cc1cc([N+](=O)[O-])ccc1F>>C[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1ccc([N+](=O)[O-])cc1C=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100240867A1,BrCCCCCCCCCCCCBr.CCCCCCCCCCCCCCCCCCCCCCO>>CCCCCCCCCCCCCCCCCCCCCCOCCCCCCCCCCCCBr,,CCCCCC,Cc1ccccc1,Cl,[H-].[Na+],test
US05366972,Cc1cc(-n2ccnc2)nc(Cl)c1C#N.O=S(=O)(O)O>>Cc1cc(-n2ccnc2)nc(Cl)c1C(N)=O,,O,O=S(=O)(O)O,[Na+].[OH-],,test
US20060004017A1,COc1cc2c(Oc3ccc(Cl)cc3F)ncnc2cc1C=CC(=O)OC(C)(C)C>>COc1cc2c(Oc3ccc(Cl)cc3F)ncnc2cc1C=CC(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20140336177A1,CCOC(=O)Cc1ccc(-n2nnnc2C)cn1>>Cc1nnnn1-c1ccc(CC(=O)O)nc1,,C1CCOC1,O,[Li+].[OH-],,test
US20050101636A1,CC(C)(C)OC(=O)C(C)(C)Br.N#CCc1ccc(O)cc1>>CC(C)(C)OC(=O)C(C)(C)Oc1ccc(CC#N)cc1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05025025,CC(=O)CCCC(=O)O.N#CCBr>>N#CCCC(=O)CCCC(=O)O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20030032663A1,CCN(CC)CCCN.CCN(CC)CCCOc1ccc([N+](=O)[O-])c(F)c1>>CCN(CC)CCCNc1cc(OCCCN(CC)CC)ccc1[N+](=O)[O-],,C1CCOC1,,,,test
US20110082209A1,Cc1cc(CC(=O)O)ccc1NC(=O)c1cc(OCc2cccc(Cl)c2)ccc1C.NC(CO)(CO)CO>>Cc1cc(CC(=O)O)ccc1NC(=O)c1cc(OCc2cccc(Cl)c2)ccc1C.NC(CO)(CO)CO,,CC(C)=O,,,,test
US04613606,COc1ccc(C(C#N)(CCC=O)C(C)C)cc1OC.COc1ccc(CC[N+](=O)[O-])cc1OC>>COc1ccc(CC(C(O)CCC(C#N)(c2ccc(OC)c(OC)c2)C(C)C)[N+](=O)[O-])cc1OC,,CC(C)O,,[F-].[K+],,test
US20150087585A1,CC(C)(C)OC(=O)N1CCO[C@@H](C(=O)N2CCCC2)C1.Cl>>Cl.O=C([C@H]1CNCCO1)N1CCCC1,,C1COCCO1,,,,test
US20100063119A1,CC(C)Oc1ccc(C2(C)NC(=O)N(CC#CCO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)C2=O)cc1>>CC(C)Oc1ccc(C2(C)NC(=O)N(CC#CCO)C2=O)cc1,,C1CCOC1,,Cl,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20130102776A1,CC(C)(C)OC(=O)N1CCNCC1.COc1cc(CBr)c2c(c1)C(=O)CO2>>COc1cc(CN2CCN(C(=O)OC(C)(C)C)CC2)c2c(c1)C(=O)CO2,,ClCCl,,CCN(CC)CC,,test
US20050176761A1,CC(=O)Nc1ccc(N)cc1.CCCCCCBr>>CCCCCCN(C(C)=O)c1ccc(N)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20040092737A1,CSC(=N)NCc1ccc2c(c1)Nc1nccnc1S2.N#CN>>N#CN=C(N)NCc1ccc2c(c1)Nc1nccnc1S2,,CN(C)C=O,,CCOC(C)=O,O,test
US20120329649A1,N#Cc1cc(C=O)ccc1F.O=[N+]([O-])c1nc[nH]n1>>N#Cc1cc(C=O)ccc1-n1cnc([N+](=O)[O-])n1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20090156603A1,CC(C)(C)OC(=O)N1CCC(c2nsc(Nc3ncc(Sc4ccnc5ccsc45)cc3Sc3ccccc3)n2)CC1.Cl.ClCCl>>Cl.Cl.c1ccc(Sc2cc(Sc3ccnc4ccsc34)cnc2Nc2nc(C3CCNCC3)ns2)cc1,,C1COCCO1,ClCCl,CO,,test
US04469868,CC(C)[C@H](N)CO.Cc1nc(Cl)c2c(n1)c(C)nn2C>>Cc1nc(NC(CO)C(C)C)c2c(n1)c(C)nn2C,,CN(C)C=O,,CCN(CC)CC,,test
US20090298807A1,CC(C)(C)[Si](C)(C)Cl.OCCc1ccc(F)cc1>>CC(C)(C)[Si](C)(C)OCCc1ccc(F)cc1,,CN(C)C=O,,c1c[nH]cn1,,test
US20110201656A1,COc1ccc(-c2nnn(-c3ccc(C(F)(F)F)cc3Cl)c2CBr)cc1.O>>COc1ccc(-c2nnn(-c3ccc(C(F)(F)F)cc3Cl)c2CO)cc1,,C1COCCO1,O,O=C([O-])[O-].[Ca+2],,test
US20120270838A1,O=C(OCc1ccccc1)c1ccc(OCCC(F)(F)F)cc1>>O=C(O)C1CCC(OCCC(F)(F)F)CC1,,CC(C)O,,[H][H],,test
US20100261732A1,CCOC(=O)CCN1CCN(c2ccccc2OC)CC1.NN>>COc1ccccc1N1CCN(CCC(=O)NN)CC1,,CCO,,O,,test
US20020004501A1,C[C@@H]1NC(=O)O[C@H]1c1ccc(C(C)(C)C)cc1>>C[C@H](N)Cc1ccc(C(C)(C)C)cc1,[Pd],CO,,O=C[O-].[NH4+],,test
US20040138286A1,C1=COCCC1.O=[N+]([O-])c1ccc2[nH]ncc2c1>>O=[N+]([O-])c1ccc2c(cnn2C2CCCCO2)c1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120071535A1,CI.OCC#Cc1ccc2c(cnn2C2CCCCO2)c1>>COCC#Cc1ccc2c(cnn2C2CCCCO2)c1,,C1CCOC1,,[H-].[Na+],,test
US20100016337A1,CC(C)(C)OC(=O)CBr.Sc1nc(-c2ccc(Cl)cc2)cs1>>CC(C)(C)OC(=O)CSc1nc(-c2ccc(Cl)cc2)cs1,,CN(C)C=O,,CCN(CC)CC,O,test
US20130210825A1,Cc1cn2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)cc2n1.Cl>>Cc1cn2nc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)cc2n1.Cl,,C1COCCO1,,,,test
US20110144105A1,COc1cnc2c(c1)cc(C(=CC1CCCC1)c1ccc(S(C)(=O)=O)cc1)n2S(=O)(=O)c1ccccc1>>COc1cnc2[nH]c(C(=CC3CCCC3)c3ccc(S(C)(=O)=O)cc3)cc2c1,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040039037A1,N#CCC#N.NCl.S=C=Nc1ccccc1>>N#Cc1c(N)nsc1Nc1ccccc1,,CCO,,C,C[O-].[Na+],test
US20030166639A1,CC(C)(C)OC(=O)Nc1cc(OCC2CC2)c(C(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-c2cccnc2)c1>>O=C1CC(c2cccc(-c3cccnc3)c2)=Nc2cc(OCC3CC3)c(C(F)(F)F)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100305096A1,Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C=O)n(C)c2n1.O=C(C1CNC1)N1CCCC1>>Cc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CC(C(=O)N4CCCC4)C3)n(C)c2n1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20050113450A1,ClCCl.O=C(O)c1ccc(S(=O)(=O)N2CCc3cc(Cl)ccc32)cc1>>COC(=O)c1ccc(S(=O)(=O)N2CCc3cc(Cl)ccc32)cc1,,ClCCl,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US06518268B1,O=C(Cl)c1ccc(Cl)c(Cl)c1.O=C1NC(=O)C(=C(O)c2ccccc2)S1>>O=C1NC(=O)C(=Cc2ccccc2OC(=O)c2ccc(Cl)c(Cl)c2)S1,,CCOC(C)=O,,C1CCOC1,,test
US04849525,C=CC(=O)[O-].CCO[PH](=O)CCCCc1ccccc1.C[Si](C)(C)Cl>>CCOP(=O)(/C=C/C(=O)OC)CCCCc1ccccc1,,CCOC(C)=O,ClC(Cl)Cl,CCN(CC)CC,,test
US20110082181A1,C=CC(C)(C)C(O)c1c(C)noc1-c1ccc(Br)cc1.CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1>>C=CC(C)(C)C(O)c1c(C)noc1-c1ccc(-c2ccc(C3(C(=O)OCC)CC3)cc2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,,,test
US20040048858A1,COCCOCCBr.COc1cc(O)c(C=O)cc1-c1cccs1>>COCCOCCOc1cc(OC)c(-c2cccs2)cc1C=O,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20060058352A1,COc1ccc(C2(C#N)CCN(C)CC2)cc1>>COc1ccc(C2(CN)CCN(C)CC2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040077670A1,COc1ccccc1Oc1c(Cl)nc(SC)nc1NS(=O)(=O)NCc1ccccc1.OCCO>>COc1ccccc1Oc1c(NS(=O)(=O)NCc2ccccc2)nc(SC)nc1OCCO,,OCCO,,O=C(O)CC(O)(CC(=O)O)C(=O)O,,test
US20090018122A1,CCOCc1nc2cnc3ccc(OCc4ccccc4)cc3c2n1CC(C)(C)N.CS(=O)(=O)OS(C)(=O)=O>>CCOCc1nc2cnc3ccc(OCc4ccccc4)cc3c2n1CC(C)(C)NS(C)(=O)=O,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US06919460B2,COOC(CBr)OOC.NC(=S)c1ccc(O)cc1>>O[C@@H](CBr)c1cccnc1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20140323468A1,Fc1ccc(OCc2cncc(-c3cnc4c(c3)CCCN4)c2)cc1.O=C=NC(=O)c1ccccc1>>NC(=O)N1CCCc2cc(-c3cncc(COc4ccc(F)cc4)c3)cnc21,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20080312226A1,O=C=Nc1ccc(C(F)(F)F)cc1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>O=C(Nc1ccc(C(F)(F)F)cc1)N1CCN(c2nc(-c3ccccc3)ns2)CC1,,C1CCOC1,,CCN(CC)CC,,test
US20120302610A1,O=C(O)CCNC(=O)c1ccc(-c2cc(C3=CCCCC3)ccc2CNc2ccc(-c3ccc(F)cc3)cc2)cn1>>O=C(O)CCNC(=O)c1ccc(-c2cc(C3CCCCC3)ccc2CNc2ccc(-c3ccc(F)cc3)cc2)cn1,[Pd],CO,,O=C[O-].[NH4+],,test
US20160130268A1,CC(C)(C)OC(=O)NCCN1CCN(C2COC2)CC1>>NCCN1CCN(C2COC2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120309842A1,C[C@@H](N)c1cccc2ccccc12.ClC=CCCl>>C[C@@H](NCC=CCl)c1cccc2ccccc12,,CC(C)O,,[I-].[K+],,test
US20110166132A1,CCOC(=O)C(C)(C#N)c1cc(C)cc(Br)c1>>Cc1cc(Br)cc(C(C)C#N)c1,,C1COCCO1,CCOC(C)=O,Cl,O=C([O-])O.[Na+],test
US20120202785A1,COCCn1c([C@H](C)N)nc2ccc(F)c(-c3ccccn3)c21.N#Cc1c(N)ncnc1Cl>>COCCn1c([C@H](C)Nc2ncnc(N)c2C#N)nc2ccc(F)c(-c3ccccn3)c21,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US05585378,Cc1ccc2c(c1)C1(OCCO1)C(=O)N2.ClCCC1CCN(Cc2ccccc2)CC1>>Cc1ccc2c(c1)C1(OCCO1)C(=O)N2CCC1CCN(Cc2ccccc2)CC1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20020035288A1,CC(C)(C)OC(=O)N1COC(=O)[C@@H]1Cc1ccccc1.Cl.ClCBr>>Cl.N[C@@H](Cc1ccccc1)C(=O)CCl,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US06087006,CC(C)C(=O)Cl.O=C(NCCO)Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>CC(C)C(=O)OCCNC(=O)Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1,,O,,ClCCl,c1ccncc1,test
US04354027,COc1ccc2c(c1)nc(NN)c(=O)n2C.O=C(Cl)C1CC1>>COc1ccc2c(c1)nc(NNC(=O)C1CC1)c(=O)n2C,,C1COCCO1,,CCN(CC)CC,,test
US20100249229A1,C=CCCC=O.O=C(O)CC(=O)O>>C=CCC/C=C/C(=O)O,,c1ccncc1,,C1CCNCC1,Cl,test
US20140073623A1,CCN(CC)C/C=C\c1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1C(=O)OC(C)(C)C)OC[C@H]1CCN21>>CCN(CC)C/C=C\c1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)OC[C@H]1CCN21,,ClCCl,O=C(O)C(F)(F)F,,,test
US05405997,BrCCCC1CC1.CCNCCCC(O)c1ccc(NS(C)(=O)=O)cc1>>CCN(CCCC1CC1)CCCC(O)c1ccc(NS(C)(=O)=O)cc1,,CC#N,,O=C([O-])O.[Na+],,test
US20110028450A1,CCCC[Sn](CCCC)(CCCC)c1cccc(F)n1.COc1cc2c(cc1Br)-c1c(-c3cncs3)c3c(n1CC2)C(=O)N(C(C)(C)C)CCOC3>>COc1cc2c(cc1-c1cccc(F)n1)-c1c(-c3cncs3)c3c(n1CC2)C(=O)N(C(C)(C)C)CCOC3,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US04642240,Nc1cc(N)cc(C(=O)O)c1.O=Cc1ccccc1>>Nc1cc(NCc2ccccc2)cc(C(=O)O)c1,,CO,,[BH3-]C#N.[Na+],,test
US20100152047A1,CC(=O)N1C(=O)C(=Cc2ccccc2Br)NC(=O)C1Cc1ccccc1>>O=C1NC(Cc2ccccc2)C(=O)NC1=Cc1ccccc1Br,,C1CCOC1,,Cl,,test
US20060189591A1,Cc1ccc(C(N)=O)cn1>>Cc1ccc(C#N)cn1,,c1ccccc1,,O=P(Cl)(Cl)Cl,,test
US20050107362A1,CC(=O)OCC(=O)O.CC(C)(C)OC(=O)CN[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1>>O=C(N[C@@H]1Cc2ccccc2[C@H]1NC[C@@H](O)CO)c1cc2cc(Cl)ccc2[nH]1,,C1CCOC1,,COc1nc(OC)nc([N+]2(C)CCOCC2)n1.[Cl-],,test
US09273028B2,CN(Cc1ccccc1)C1COCCN(C(=O)OC(C)(C)C)C1>>CNC1COCCN(C(=O)OC(C)(C)C)C1,[Pd],CO,,O=CO,,test
US20060264457A1,CCOC(=O)c1c(C)nc2cn(Cc3ccccc3)cc2c1-c1ccc(Cl)cc1Cl>>Cc1nc2cn(Cc3ccccc3)cc2c(-c2ccc(Cl)cc2Cl)c1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080214503A1,CCOP(=O)(CCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(C)c1=O)OCC>>Cn1c(=O)c(C(=O)NCCP(=O)(O)O)c(O)c2ncc(Cc3ccc(F)cc3)cc21,,Cl,,,,test
US20140256933A1,O=C(NC1=NC2(c3ccccc3F)CN(c3ncc(F)cn3)CC2CS1)c1ccccc1>>NC1=NC2(c3ccccc3F)CN(c3ncc(F)cn3)CC2CS1,,CO,,[Li+].[OH-],,test
US20110021487A1,CC(C)(C)[Si](C)(C)Cl.O=Cc1ccc(O[C@@H]2COC[C@H]2O)cc1>>CC(C)(C)[Si](C)(C)O[C@@H]1COC[C@H]1Oc1ccc(C=O)cc1,,ClCCl,,CCN(CC)CC,,test
US04591584,COC(=O)c1ccc([N+](=O)[O-])cc1O.CS(=O)(=O)Cl>>COC(=O)c1ccc([N+](=O)[O-])cc1OS(C)(=O)=O,,CCN(CC)CC,ClC(Cl)Cl,,,test
US20060111347A1,CC(=O)OC(C)(C)C.CC(C)(C=O)S(=O)(=O)c1cccc(C(F)(F)F)c1>>CC(C)(C)OC(=O)CC(O)C(C)(C)S(=O)(=O)c1cccc(C(F)(F)F)c1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US06043373,Nc1nc2c(s1)C(=O)CCC2.O=C(CBr)c1ccccc1>>O=C1CCCc2c1sc1nc(-c3ccccc3)cn21,,CN(C)C=O,,,,test
US05300668,C=CC1CC1(C(=O)OC)c1ccc(CO[Si](C)(C)C(C)(C)C)cc1>>COC(=O)C1(c2ccc(CO)cc2)CC=CC1,,C1CCOC1,,Cl,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05272163,Nc1ccc(S(=O)(=O)c2ccccc2)cc1.O=C(O)C(O)(C(F)F)C(F)F>>O=C(Nc1ccc(S(=O)(=O)c2ccccc2)cc1)C(O)(C(F)F)C(F)F,,CC(=O)N(C)C,O,O=S(Cl)Cl,O=C([O-])O.[Na+],test
US06355659B1,Clc1ccc(C2=CCN(CCCCn3cncn3)CC2)cc1.O=P(O)(O)O>>Clc1ccc(C2=CCN(CCCCn3cncn3)CC2)cc1.O=P(O)(O)O,,CC(C)O,,,,test
US20140039207A1,C[C@H]1CO[C@@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(OCOC(=O)OCC(=O)OCc4ccccc4)c3C(=O)N12>>C[C@H]1CO[C@@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(OCOC(=O)OCC(=O)O)c3C(=O)N12,[Pd],CCOC(C)=O,CO,[H][H],,test
US20060258860A1,COC(=O)c1nc([C@@H]2C[C@@H](OCc3ccccc3)CN2C(=O)c2ccccc2)n(C)c(=O)c1OC(=O)c1ccccc1.NCc1ccc(F)cc1>>Cn1c([C@@H]2C[C@@H](OCc3ccccc3)CN2C(=O)c2ccccc2)nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O,,CO,,,,test
US20120142665A1,CCOC(=O)c1cnn(C)c1C(=O)Nc1ccn2nc(N(C)C)nc2c1>>CN(C)c1nc2cc(NC(=O)c3c(C(=O)O)cnn3C)ccn2n1,,CO,O,[Li+].[OH-],,test
US20150259354A1,C1=COCCC1.O=[N+]([O-])c1ccc(CO)c(F)c1>>O=[N+]([O-])c1ccc(COC2CCCCO2)c(F)c1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05739336,COc1cc(OC)c(C(=O)CCCCCl)cc1N.O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1>>COc1cc(OC)c(C(=O)CCCCCl)cc1NS(=O)(=O)c1ccc(C(F)(F)F)cc1,,C1CCOC1,,,,test
US20130203735A1,NC(=NO)C1CCCN(c2ccc(F)cc2)C(=O)C1.O=C(Cl)c1ccc(F)cc1>>NC(=NOC(=O)c1ccc(F)cc1)C1CCCN(c2ccc(F)cc2)C(=O)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150266895A1,CNc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(NC(=O)NC(c3ccccc3)C3CCCO3)ncc12>>CNc1n[nH]c2cc(NC(=O)NC(c3ccccc3)C3CCCO3)ncc12,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20060004012A1,CN(C)C(=O)C(CC(=O)OC(C)(C)C)c1ccc(OCc2cccc(-c3ccc(C(F)(F)F)cc3)c2)cc1>>CN(C)C(=O)C(CC(=O)O)c1ccc(OCc2cccc(-c3ccc(C(F)(F)F)cc3)c2)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20120329818A1,CN(C)CCC1(C(=O)Nc2cccc(OC(=O)N(C)C)c2)CCNCC1.Cc1c[nH]c2ncnc(Cl)c12>>Cc1c[nH]c2ncnc(N3CCC(CCN(C)C)(C(=O)Nc4cccc(OC(=O)N(C)C)c4)CC3)c12,,CC(C)CO,,CCN(C(C)C)C(C)C,,test
US20130079340A1,Nc1ccc2nc(N3CCN(C4CC4)CC3)sc2c1.O=S(=O)(Cl)CCCCl>>O=S1(=O)CCCN1c1ccc2nc(N3CCN(C4CC4)CC3)sc2c1,,CN(C)C=O,,[H-].[Na+],,test
US20100121052A1,CC(=O)O.Nc1ccc2nc(Nc3ccc(S(N)(=O)=O)cc3)ncc2c1>>CC(=O)Nc1ccc2nc(Nc3ccc(S(N)(=O)=O)cc3)ncc2c1,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150316557A1,CCN(CC)c1ccc2cc(C(=O)Nc3cc(NC(=O)OC(C)(C)C)cc(N4C(=O)C=C(C)C4=O)c3)c(=O)oc2c1>>CCN(CC)c1ccc2cc(C(=O)Nc3cc(N)cc(N4C(=O)C=C(C)C4=O)c3)c(=O)oc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160194292A1,C=CC#N.Cc1cc(C=O)ccc1Br>>Cc1cc(C(=O)CCC#N)ccc1Br,,CN(C)C=O,,[C-]#N.[Na+],,test
US20120077828A1,CC(C)(C)OC(=O)N1CCc2c(Cl)cccc21.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N1CCc2c1ccc(Br)c2Cl,,ClCCl,,O=C([O-])O.[Na+],,test
US07413727B2,CC(C)(C)OC(=O)CBr.Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1>>CC(C)(C)OC(=O)CN1C=CN(CC(OCc2ccc(Cl)cc2)c2ccc(Cl)cc2Cl)C1,,CC#N,,,,test
US20080214549A1,C1=C2CCCCNN2CCC1.CCOC(=O)C(=O)C(C)C.CCOC(=O)c1c(O)c(C(C)C)nn(Cc2ccccc2)c1=O>>CC(C)c1nn(Cc2ccccc2)c(=O)c(C(=O)NCC(=O)O)c1O,,CCOC(C)=O,ClCCl,CC(=O)O,Cl,test
US20140045819A1,CC(=O)NN.S=C1CCc2cc(Br)ccc2N1>>Cc1nnc2n1-c1ccc(Br)cc1CC2,,CCCCO,O,,,test
US20150266857A1,CC(C)(C)CS(=O)(=O)N(Cc1nc2ccc(-c3c[nH]c4cc(F)ccc34)cc2o1)C(=O)OC(C)(C)C>>CS(=O)(=O)NCc1nc2ccc(-c3c[nH]c4cc(F)ccc34)cc2o1,,C1COCCO1,Cl,,,test
US05985858,CCOP(OCC)OCC.O=C(O)c1ccc(CBr)s1>>CCOP(=O)(Cc1ccc(C(=O)O)s1)OCC,,CCO,,ClCCl,[Na+].[OH-],test
US20100152160A1,CN.COC(=O)c1cc2c(cc1Cl)NCC(C(=O)N1CCC(C#N)(Cc3ccc(F)cc3)CC1)O2>>CNC(=O)c1cc2c(cc1Cl)NCC(C(=O)N1CCC(C#N)(Cc3ccc(F)cc3)CC1)O2,,C1CCOC1,,,,test
US20080227811A1,CS(=O)(=O)Cl.O=C(NC1(CO)CC1)OCc1ccccc1>>CS(=O)(=O)OCC1(NC(=O)OCc2ccccc2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110021520A1,CCOC(=O)COCC(NC(=O)OC(C)(C)C)(c1cccc(Br)c1)C(F)(F)F>>CCOC(=O)COCC(N)(c1cccc(Br)c1)C(F)(F)F,,ClCCl,,C1COCCO1,Cl,test
US20150152068A1,CC#CC(=O)N[C@@H](C)COc1c(-c2cc(F)cc(N(C(=O)OC(C)(C)C)C(=O)c3ccc(C4CC4)cc3)c2C)ncnc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.CI>>CC#CC(=O)N(C)[C@@H](C)COc1c(-c2cc(F)cc(N(C(=O)OC(C)(C)C)C(=O)c3ccc(C4CC4)cc3)c2C)ncnc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,CN(C)C=O,,Cl,[H-].[Na+],test
US20030008768A1,COc1ccccc1Br.OB(O)c1ccc(C(F)(F)F)cc1>>COc1ccccc1-c1ccc(C(F)(F)F)cc1,,C1CCOC1,,[F-].[K+],,test
US20090156605A1,COC(=O)CCC(=O)c1c(O)c2cc(C3=CCCCC3)cnc2n(C)c1=O.Cn1c(=O)c(C(=O)CCC(=O)O)c(O)c2cc(I)cnc21>>Cn1c(=O)c(C(=O)CCC(=O)O)c(O)c2cc(C3CCCCC3)cnc21,[Pd],,,C1=CCCCC1,,test
US20030114443A1,CS(=O)(=O)Cl.O=C(NC1CCNCC1)N(CCCN1CCC(Cc2ccccc2)CC1)c1ccccc1>>CS(=O)(=O)N1CCC(NC(=O)N(CCCN2CCC(Cc3ccccc3)CC2)c2ccccc2)CC1,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20090209532A1,O=C(c1sc2cc(O)c(O)cc2c1Cl)N1CCC(O)CC1.O=[N+]([O-])O>>O=C(c1sc2c([N+](=O)[O-])c(O)c(O)cc2c1Cl)N1CCC(O)CC1,,CCOC(C)=O,ClCCl,,,test
US04229595,Cc1cccc(O)c1.O=[N+]([O-])O>>Cc1cc(O)ccc1[N+](=O)[O-],,O,,,,test
US20130131016A1,C=C(Br)C(F)(F)F.OB(O)c1ccc(F)c(Cl)c1>>C=C(c1ccc(F)c(Cl)c1)C(F)(F)F,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20080119518A1,COC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.COc1cccc(Oc2cccc(Br)n2)c1C=O>>CO/C=C/c1c(OC)cccc1Oc1cccc(Br)n1,,C1CCOC1,O,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US20100278833A1,CCN.C[C@@H](Oc1cc(-n2cnc3cc(COS(C)(=O)=O)ncc32)sc1C(N)=O)c1ccccc1C(F)(F)F>>CCNCc1cc2ncn(-c3cc(O[C@H](C)c4ccccc4C(F)(F)F)c(C(N)=O)s3)c2cn1,,CO,,,,test
US20060223795A1,C[C@@H](COc1ccc(Br)cc1)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>C[C@@H](COc1ccc(Br)cc1)CO[Si](C)(C)C(C)(C)C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20070167476A1,CC(C)(C)OC(=O)N1CCn2c(nc3c(N)nc4cc(OCc5ccccc5)ccc4c32)C1>>Nc1nc2cc(OCc3ccccc3)ccc2c2c1nc1n2CCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040122080A1,COC(=O)c1ccc(-c2ccc3cc4c(cc3c2)C(c2cccc(C)c2)=CCC4(C)C)cc1.O=[Se]=O>>COC(=O)c1ccc(-c2ccc3cc4c(cc3c2)C(c2cccc(C)c2)=CC(=O)C4(C)C)cc1,,C1COCCO1,CCOC(C)=O,,,test
US20130029968A1,C1=COCCC1.CCc1cc(OC)c(F)cc1-c1ccc2c(I)n[nH]c2c1>>CCc1cc(OC)c(F)cc1-c1ccc2c(I)nn(C3CCCCO3)c2c1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US06054457,COc1cc(C(=O)N(C)c2ccc(C)cc2OCCCCCC(=O)N2CCC(N(C)C)CC2)ccc1NC(=O)c1ccccc1OC(C)=O>>COc1cc(C(=O)N(C)c2ccc(C)cc2OCCCCCC(=O)N2CCC(N(C)C)CC2)ccc1NC(=O)c1ccccc1O,,CO,,[Na+].[OH-],,test
US20160060260A1,Cn1c(=O)n(C)c2cc([N+](=O)[O-])ccc21>>Cn1c(=O)n(C)c2cc(N)ccc21,[Pd],CCOC(C)=O,,[H][H],,test
US06124283,CC(=O)Oc1ccccc1C(=O)Cl.CN1CCN(c2cccc3c2C[C@H](N)CC3)CC1>>CN1CCN(c2cccc3c2C[C@H](NC(=O)c2ccccc2O)CC3)CC1,,ClCCl,,CCN(CC)CC,,test
US20070049632A1,CCOC(=O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)nc1C(F)(F)F>>OCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)nc1C(F)(F)F,,C1CCOC1,C1CCOC1,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090131468A1,COC(=O)c1ccc(Br)c(O)c1.OCCC(F)(F)F>>COC(=O)c1ccc(Br)c(OCCC(F)(F)F)c1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05340701,CC(C)CCOc1cc(Cl)nc(Cl)n1.CC(C)CS>>CC(C)CCOc1cc(Cl)nc(SCC(C)C)n1,,C1CCOC1,,O,[H-].[Na+],test
US20120122940A1,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCOC(CC)(CC)C(=O)OC(C)(C)C>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCOC(CC)(CC)C(=O)O,,O=CO,,,,test
US20100216837A1,CC(C)(C)OC(=O)NC(c1ccccc1F)C(C)(C)C(=O)O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1C(=O)NC(C)(C)C1c1ccccc1F,,CN(C)C=O,,CCN(CC)CC,,test
US05260297,O=C(N=c1sc2cc(C(F)(F)F)ccc2n1CCN1CCN(c2ccc(F)cc2)CC1)C(F)(F)F>>N=c1sc2cc(C(F)(F)F)ccc2n1CCN1CCN(c2ccc(F)cc2)CC1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US05856503,COc1cccc(CCNC(=O)c2ccc(Br)cc2)c1>>COc1ccc2c(c1)CCN=C2c1ccc(Br)cc1,,CC#N,,O=P(Cl)(Cl)Cl,,test
US20150175594A1,Cc1nsc(-c2c(N)sc3c2CCCC3)n1.O=C1OC(=O)C2=C1CCC2>>Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCC3)sc3c2CCCC3)n1,,CO,ClCCl,,,test
US04552876,O=[N+]([O-])c1cc(CCCCCc2ccc(O)c([N+](=O)[O-])c2)ccc1O>>Nc1cc(CCCCCc2ccc(O)c(N)c2)ccc1O,[Pd],CCOC(C)=O,,CO,,test
US20020111358A1,CCOC(=O)c1cc2cccc(OC[C@@H](O)CN3CCC(c4ccc5ccccc5c4)CC3)c2o1>>O=C(O)c1cc2cccc(OC[C@@H](O)CN3CCC(c4ccc5ccccc5c4)CC3)c2o1,,CO,,Cl,[Na+].[OH-],test
US20150376136A1,CN1C(=O)NC(=O)C1(C)C1CCCCC1.O=C(CBr)c1ccc([N+](=O)[O-])cc1>>CN1C(=O)N(CC(=O)c2ccc([N+](=O)[O-])cc2)C(=O)C1(C)C1CCCCC1,,CN(C)C=O,,[H-].[Na+],,test
US20120202287A1,CCCCC[C@H]([C@H](C)O[Si](C)(C)C(C)(C)C)n1cnc2c(Cl)ncnc21.N>>CCCCC[C@H]([C@H](C)O[Si](C)(C)C(C)(C)C)n1cnc2c(N)ncnc21,,CO,ClCCl,,,test
US20090286765A1,N#Cc1ccc(F)cc1.Sc1c[nH]nn1>>N#Cc1ccc(Sc2c[nH]nn2)cc1,,CN(C)C=O,,[Na],,test
US20080182842A1,CC(C)(C)OC(=O)N1CCOc2ccc(CCO)nc21.COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C>>COC(=O)[C@H](Cc1ccc(OCCc2ccc3c(n2)N(C(=O)OC(C)(C)C)CCO3)cc1)NC(=O)OC(C)(C)C,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US03998829,CC(=O)OC(C)=O.C[C@]12CC(=O)[C@H]3[C@@H](CC[C@H]4C[C@H](OC5CCCCO5)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)CCO>>CC(=O)OCCC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C,,c1ccncc1,,,,test
US20050085465A1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCN(C(C)=O)CC1.Oc1ccc2[nH]ccc2c1F>>COc1cc2c(Oc3ccc4[nH]ccc4c3F)ncnc2cc1OCCCN1CCN(C(C)=O)CC1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20070010573A1,CCC(N)CC.O=S1(=O)CCCO1>>CCC(CC)NCCCS(=O)(=O)O,,C1CCOC1,C1CCOC1,,,test
US05246929,O=C1Nc2ccccc2SC1Cl.c1ccsc1>>O=C1Nc2ccccc2SC1c1cccs1,,ClCCl,,,,test
US20100022583A1,C=C(C)CBr.COC(=O)Cc1cc(-c2ccc(C(F)(F)F)cc2)nc(N(CC(C)C)c2ccc(C(F)(F)F)cc2)c1>>C=C(C)CC(C(=O)OC)c1cc(-c2ccc(C(F)(F)F)cc2)nc(N(CC(C)C)c2ccc(C(F)(F)F)cc2)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20060025459A1,C[C@H](NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc(N2CCCC2=O)cc([N+](=O)[O-])c1)C(=O)NC1CCCCC1>>C[C@H](NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc(N)cc(N2CCCC2=O)c1)C(=O)NC1CCCCC1,[Pd],O,,CCO,,test
US20050014941A1,CSc1ccc(S(=O)(=O)C[C@@H]2CCCC[C@H]2C(=O)NCC#N)cc1.SCCc1ccccc1>>N#CCNC(=O)[C@@H]1CCCC[C@H]1CS(=O)(=O)c1ccc(SCCc2ccccc2)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070197478A1,CCOC(=O)N(Cc1ccccc1)c1cc(Br)nc(N)c1[N+](=O)[O-].CO>>CCOC(=O)N(Cc1ccccc1)c1cc(OC)nc(N)c1[N+](=O)[O-],,C1CCOC1,,[H-].[Na+],,test
US09434690B2,COS(=O)(=O)OC.O=c1[nH][nH]c2cc([N+](=O)[O-])ccc12>>Cn1[nH]c2cc([N+](=O)[O-])ccc2c1=O,,CN(C)C=O,ClCCl,O=C([O-])[O-].[Na+].[Na+],,test
US20150336931A1,C=CCC1(O)CCN(C(=O)OC(C)(C)C)CC1.C[Si](C)(C)C(F)(F)F>>CC(C)(C)OC(=O)N1CCC(O)(CC2CC2(F)F)CC1,,ClCCl,,C1CCOC1,,test
US20110172237A1,CO.O=C(O)C1(c2ccccc2)CCCCCC1>>COC(=O)C1(c2ccccc2)CCCCCC1,,CO,Cc1ccccc1,C[Si](C)(C)C=[N+]=[N-],,test
US20150368247A1,CNC(=O)Oc1ccc([N+](=O)[O-])cc1.C[C@H]1CC[C@H](Cn2cnc3nc(C(=O)NN)nc(N[C@H](C)C4CCC4)c32)CC1>>CNC(=O)NNC(=O)c1nc(N[C@H](C)C2CCC2)c2c(ncn2C[C@H]2CC[C@H](C)CC2)n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US06197729B1,OC1CCC(C(O)C(F)(F)F)CC1>>O=C1CCC(C(O)C(F)(F)F)CC1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20110213143A1,CCOC(=O)C(Cc1ncn2c1CCc1ccccc1-2)c1ccnc(N(Cc2ccc(OC)cc2)Cc2ccc(OC)cc2)c1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2cc(C(Cc3ncn4c3CCc3ccccc3-4)C(=O)O)ccn2)cc1,,CO,,[Na+].[OH-],,test
US08455528B2,CI.N#Cc1ccc(-c2nc(-c3ccccc3)[nH]c2Sc2ccc(Cl)cc2)cc1>>Cn1c(-c2ccccc2)nc(-c2ccc(C#N)cc2)c1Sc1ccc(Cl)cc1,,C1CCOC1,,[H-].[Na+],,test
US20010047018A1,FCCBr.O=[N+]([O-])c1ccc2c(c1)CS(=O)(=O)N2>>O=[N+]([O-])c1ccc2c(c1)CS(=O)(=O)N2CCF,,O,,O=C([O-])O.[Na+],,test
US20160137659A1,CCc1cc(C(C)=O)c(O)cc1Br.O=C1COC1>>CCc1cc2c(cc1Br)OC1(COC1)CC2=O,,CC(C)O,,C1CCNC1,,test
US20060252751A1,O=C(c1cnc(C2(O)CCC3(CC2)OCCO3)s1)N1CCCC1.O=S(Cl)Cl>>O=C(c1cnc(C2(Cl)CCC3(CC2)OCCO3)s1)N1CCCC1,,c1ccncc1,,,,test
US20110028455A1,CCc1ncc(C#N)c(Cl)c1I.Cc1c(N)ccc2[nH]ccc12>>CCc1ncc(C#N)c(Nc2ccc3[nH]ccc3c2C)c1I,,CCO,,O,,test
US20130072467A1,C[C@H](N)C(=O)N(C)C.O=C1NC(=S)CS1>>C[C@H](NC1=NC(=O)SC1)C(=O)N(C)C,,CCO,,CCN(CC)CC,,test
US20070105919A1,CNC.O=C(Nc1nc(-c2ccco2)c(C(=O)c2ccccc2)s1)c1ccnc(CCl)c1>>CN(C)Cc1cc(C(=O)Nc2nc(-c3ccco3)c(C(=O)c3ccccc3)s2)ccn1,,CO,,O,,test
US20140336190A1,Cc1noc(C)c1-c1cc([N+](=O)[O-])c(N)c(S(=O)(=O)NC2CCCC2)c1>>Cc1noc(C)c1-c1cc(N)c(N)c(S(=O)(=O)NC2CCCC2)c1,[Pd],CO,,,,test
US05063243,N#CCC(=O)O.OCCc1ccccc1>>N#CCC(=O)OCCc1ccccc1,CN(C)c1ccncc1,CN(C)C=O,,,,test
US04954520,CCCCCCCCCC/C=C/C=C/C=O.COC(=O)CCCC(O)CO>>CCCCCCCCCC/C=C/C=C/C1OCC(CCCC(=O)OC)O1,,c1ccccc1,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20080194549A1,CCN.COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2C=O)C(C)C)ccc1OC>>CCNC[C@@H]1CNC[C@H]1CN(C(=O)c1ccc(OC)c(OCCCOC)c1)C(C)C,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090215829A1,Brc1ccccc1OCCNCc1ccccc1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N(CCOc1ccccc1Br)Cc1ccccc1,,ClCCl,,,,test
US20100261910A1,C#CC1=CCCCC1.Cc1ccc(S(=O)(=O)Oc2cccc(C(F)(F)F)c2)cc1>>FC(F)(F)c1cccc(C#CC2=CCCCC2)c1,,CCCCCCC,,,,test
US20090076046A1,CC(C)[Si](C(C)C)(C(C)C)n1cc(C(O)c2sc(N(C)Cc3ccc(Cl)cc3)nc2Cl)c2cccnc21>>CN(Cc1ccc(Cl)cc1)c1ncc(C(=O)c2c[nH]c3ncccc23)s1,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20110152247A1,O=C(O)/C=C\C(=O)O.O=C1NC(=O)C(Cc2ccc3c(c2)CN(c2ccccn2)CCO3)S1>>O=C(O)/C=C\C(=O)O.O=C1NC(=O)C(Cc2ccc3c(c2)CN(c2ccccn2)CCO3)S1,,CO,,,,test
US20140249126A1,CCOC(=O)c1c[nH]c2c(F)c(OC)c(OC)cc2c1=O.CCOP(=O)(OCC)OCC>>CCOC(=O)c1cn(CC)c2c(F)c(OC)c(OC)cc2c1=O,,O,,O=C([O-])[O-].[K+].[K+],,test
US20140179715A1,CN1CCn2c1cc(Cl)nc2=O.OCc1ccc(Oc2ccnc(C(F)(F)F)c2)c(F)c1>>CN1CCn2c1cc(OCc1ccc(Oc3ccnc(C(F)(F)F)c3)c(F)c1)nc2=O,,C1CCOC1,,[H-].[Na+],,test
US20100184761A1,CC(=O)Cl.CNCCCOc1ccc(-c2cc3c(ncn3C)c(C#N)n2)cc1C(F)(F)F>>CC(=O)N(C)CCCOc1ccc(-c2cc3c(ncn3C)c(C#N)n2)cc1C(F)(F)F,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20160046643A1,COCCOCCOCCOCCOC1CN(C2CC3(CCOCC3)N(O)C3(CCOCC3)C2)C(=O)N(C2CC3(CCOCC3)N(O)C3(CCOCC3)C2)C1.O=C1CCOCC1>>O=C1CC2(CCOCC2)NC2(CCOCC2)C1,,CS(C)=O,O,Cl,[Cl-].[NH4+],test
US20050119256A1,CCOC(=O)CC(=O)CCl.NC(=O)c1ccc2ccccc2c1>>O=C(O)Cc1coc(-c2ccc3ccccc3c2)n1,,CCOC(C)=O,,,,test
US20100087448A1,CC(=O)Nc1nc(C#N)cs1.[Cl-].[NH4+]>>CC(=O)Nc1nc(C(=N)N)cs1.Cl,,CO,,C[O-].[Na+],,test
US20050187390A1,CC(=O)c1ccc[nH]1.O=C(O)c1ccc2c(c1)nc(-c1ccc3nc(-c4cc(Br)ccc4O)ccc3c1)n2C1CCCCC1>>O=C(O)c1ccc2c(c1)nc(-c1ccc3nc(-c4ccc[nH]4)ccc3c1)n2C1CCCCC1,,CCO,,[K+].[OH-],,test
US20060063805A1,CO.Clc1ccnc2ccc(Br)cc12>>COc1ccnc2ccc(Br)cc12,,CO,,C[O-].[Na+],,test
US20130079328A1,COc1cc(CN)ccn1>>NCc1cc[nH]c(=O)c1,,Cl,,,,test
US20040181064A1,CS(C)=O.Nc1cccc(Cl)c1F.O>>Nc1ccc(C=O)c(Cl)c1F,Cl[Cu]Cl,O,,Cl,[Na+].[OH-],test
US20050209241A1,CC(C)(C)OC(=O)N1CCN(c2cncc(Cl)n2)CC1.O=C(O)C(F)(F)F>>Clc1cncc(N2CCNCC2)n1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20040186132A1,CC1=CC(C)(C)N(C(=O)OC(C)(C)C)c2ccc(Br)cc21.COB(OC)OC>>CC1=CC(C)(C)N(C(=O)OC(C)(C)C)c2ccc(B(O)O)cc21,,C1CCOC1,,[Li]C(C)(C)C,,test
US04503045,CCC(=O)OC[C@H]1O[C@@H](n2cc(F)c(=O)[nH]c2=O)C[C@@H]1OC(=O)CC.O=C(Cl)c1cccc(F)c1>>CCC(=O)OC[C@H]1O[C@@H](n2cc(F)c(=O)n(C(=O)c3cccc(F)c3)c2=O)C[C@@H]1OC(=O)CC,,C1COCCO1,,CCN(CC)CC,,test
US20070054935A1,COc1ccc([Mg]Br)cc1F.N#Cc1cccc(-c2ccncc2C=O)c1>>COc1ccc(C(O)c2cnccc2-c2cccc(C#N)c2)cc1F,,C1CCOC1,,,,test
US05116992,CCCCCCCCCCCCCCCCCCN(C)CC(O)COC(c1ccccc1)(c1ccccc1)c1ccccc1.CN=C=O>>CCCCCCCCCCCCCCCCCCN(C)CC(COC(c1ccccc1)(c1ccccc1)c1ccccc1)OC(=O)NC,,c1ccccc1,,c1ccncc1,,test
US04806549,CCCC(=O)c1cnc2c(C)cccc2c1Cl.Nc1ccccc1Cl>>CCCC(=O)c1cnc2c(C)cccc2c1Nc1ccccc1Cl,,C1COCCO1,,,,test
US20030212070A1,CCN1CCCC1CN.O=C(Nc1ccc(Oc2ccccc2)cc1)Nc1ccc(F)c([N+](=O)[O-])c1>>CCN1CCCC1CNc1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1[N+](=O)[O-],,CCCCCC,CCOC(C)=O,,,test
US20050049259A1,CCCCNc1cccc2c(-c3ccnc(S(C)=O)n3)c(-c3ccc(F)cc3)nn12.NCCCO>>CCCCNc1cccc2c(-c3ccnc(NCCCO)n3)c(-c3ccc(F)cc3)nn12,,C1CCOC1,,,,test
US20160122344A1,CCOC(=O)c1cn2c(cc1=O)-c1cc(OCC)c(OCC)cc1CC2CN1C(=O)c2ccccc2C1=O>>CCOC(=O)c1cn2c(cc1=O)-c1cc(OCC)c(OCC)cc1CC2CN,,CCO,O,NN,,test
US20050009859A1,Nc1c(C(F)(F)F)n[nH]c1-c1ccccc1.O=C(Cl)c1ccccc1>>O=C(Nc1c(C(F)(F)F)n[nH]c1-c1ccccc1)c1ccccc1,,ClCCl,,c1ccncc1,,test
US20120264737A1,COC(=O)c1cc(-c2nc3c([nH]2)CN(C(=O)OC(C)(C)C)CC3)c(C)cc1C>>Cc1cc(C)c(-c2nc3c([nH]2)CN(C(=O)OC(C)(C)C)CC3)cc1C(=O)O,,CO,O,[Na+].[OH-],,test
US20040162278A1,CCCCC(=O)NN.CN(C)C=O.CN1CCCC1=O.ClCCl.O=C(Cl)C(=O)Cl>>CCCCC(=O)NNC(=O)C1CCN(c2ccccn2)CC1,CN(C)C=O,ClCCl,O,Cl,,test
US06610688B2,O=C1Cc2c(ncnc2Nc2ccc(F)c(Cl)c2)N1.O=Cc1ccc(C(=O)N2CCOCC2)[nH]1>>O=C1Nc2ncnc(Nc3ccc(F)c(Cl)c3)c2C1=Cc1ccc(C(=O)N2CCOCC2)[nH]1,C1CCNCC1,CCO,,,,test
US05807892,O=C1CC2C(CC(OC(=O)c3ccccc3)C2/C=C/[C@H](O)C2CCCCC2)O1>>O=C1C[C@@H]2[C@@H](/C=C/[C@H](O)C3CCCCC3)[C@H](O)C[C@@H]2O1,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20040248985A1,Cl.O=CNc1cc([C@@H](O)CNCCc2ccc(NC[C@H](O)c3ccccc3)cc2)ccc1OCc1ccccc1>>Cl.O=CNc1cc([C@@H](O)CNCCc2ccc(NC[C@H](O)c3ccccc3)cc2)ccc1OCc1ccccc1,,CC(C)O,,C1COCCO1,,test
US05489593,COC(=O)C(=Cc1ccc(OC)cc1)N=[N+]=[N-]>>COC(=O)c1cc2ccc(OC)cc2[nH]1,,Cc1ccccc1,,,,test
US20140155389A1,C1COCCN1.C=Cc1cc(Nc2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc2OC)c2c(=O)[nH]ncc2n1>>COc1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1cc(CCN2CCOCC2)nc2cn[nH]c(=O)c12,,CO,,CC(=O)O,,test
US20100056531A1,CCOC(=O)CN(C(=O)C1CCCCN1C(=O)OCc1ccccc1)c1c[nH]c2cccnc12>>O=C1C2CCCCN2C(=O)CN1c1c[nH]c2cccnc12,[Pd],CO,,,,test
US20160272596A1,COc1ccc2cc(Br)ccc2c1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)CNc2ccccc21.N#Cc1ccc(CBr)cc1>>COc1ccc2cc(Br)ccc2c1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)CN(Cc2ccc(C#N)cc2)c2ccccc21,,CCOC(C)=O,CN(C)C=O,[I-].[Na+],O=C([O-])[O-].[Cs+].[Cs+],test
US06136852,CCOC(=O)CCc1ccc2c(c1)C[C@@H](NC(=O)OC(C)(C)C)CC2>>CCOC(=O)CCc1ccc2c(c1)C[C@@H](N)CC2,,CCO,,Cl,,test
US20090143361A1,COc1ccc2nc(Cl)c3c(C(F)(F)F)ncn3c2n1.O=C1CCC(=O)N1Br>>COc1ccc2nc(Cl)c3c(C(F)(F)F)nc(Br)n3c2n1,,CC#N,,O=S([O-])[O-].[Na+].[Na+],,test
US20150152108A1,FC(F)(F)[C@@H]1CCCN1c1ccc2c(n1)N[C@H]1CCCN2C1.O=c1nc2ccccn2c(=O)n1-c1ccccn1>>O=C(Nc1ccccn1)N1c2nc(N3CCC[C@H]3C(F)(F)F)ccc2N2CCC[C@H]1C2,,C1CCOC1,,[H-].[Na+],,test
US20120322802A1,COC(=O)Cc1ccccc1.COc1cc(OC)nc(S(C)(=O)=O)n1.O>>COC(=O)C(Oc1nc(OC)cc(OC)n1)c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160120850A1,COC(=O)C(C)(C)CC(=O)O.N=C(NO)c1nc(CC2CCC2)cs1>>COC(=O)C(C)(C)Cc1nc(-c2nc(CC3CCC3)cs2)no1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070004776A1,CC(C)(C)OC(=O)NC(Cc1ccc(Oc2ccc(C(=O)NOCc3ccccc3)cc2)cc1)C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NC(Cc1ccc(Oc2ccc(C(=O)NO)cc2)cc1)C(=O)O,[Pd],CO,,[H][H],,test
US20150361095A1,C[C@H](NC(=O)OC(C)(C)C)c1nc2c(Cl)ccc(Cl)c2c(=O)n1-c1cccc(N)c1.NCCCO.O=C(Cl)Oc1ccccc1>>C[C@H](NC(=O)OC(C)(C)C)c1nc2c(Cl)ccc(Cl)c2c(=O)n1-c1cccc(NC(=O)NCCCO)c1,CN(C)c1ccncc1,C1CCOC1,,CN(C)C=O,,test
US05968944,CCc1nn(-c2c(C)cc(Br)cc2C)c(CC)c1CO.OCC1Cc2ccccc2CN1>>CCc1nn(-c2c(C)cc(Br)cc2C)c(CC)c1CN1Cc2ccccc2C[C@@H]1CO,,CN(C)C=O,,CCN(CC)CC,ClCCl,test
US20160264567A1,Fc1c(-c2cnc(C(F)(F)F)nc2)cc(CBr)nc1Br.N>>NCc1cc(-c2cnc(C(F)(F)F)nc2)c(F)c(Br)n1,,C1COCCO1,,,,test
US20150053900A1,COC(=O)c1ccc(O)cc1.N#Cc1c(Cl)c(Cl)c(Cl)c(Cl)c1C#N>>COC(=O)c1ccc(Oc2c(Cl)c(Cl)c(C#N)c(C#N)c2Cl)cc1,,CCOC(C)=O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20050176736A1,CCOC(=O)CC(=O)OCC.N#Cc1ccc(Br)cc1>>CCOC(=O)C(C(=O)OCC)c1ccc(C#N)cc1,,C1COCCO1,,Cl,[H-].[Na+],test
US05723471,CSc1nccc(Cl)n1.OCC(F)(F)F>>CSc1nccc(OCC(F)(F)F)n1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20110046097A1,Fc1ncccc1I.NN>>NNc1ncccc1I,,CCO,,O,,test
US05225584,COC(OC)OC.COc1cccc(C=O)c1>>COc1cccc(C(OC)OC)c1,,CO,,O=C([O-])O.[Na+],,test
US20060025432A1,C1CCNCC1.NS(N)(=O)=O>>NS(=O)(=O)N1CCCCC1,,C1COCCO1,,,,test
US04186132,CC1C(=S)N(C)c2ccccc21.O=C1CCC(=O)N1Cl>>CN1C(=S)C(C)(Cl)c2ccccc21,,ClC(Cl)(Cl)Cl,,,,test
US20100261732A1,COc1ccccc1N1CCN(CCC(=O)NNC(=O)Nc2ccccc2)CC1>>COc1ccccc1N1CCN(CCc2n[nH]c(=O)n2-c2ccccc2)CC1,,[Na+],[OH-],Cl,,test
US20090030012A1,Cc1cn(CC(=O)OC(C)(C)C)c(C)n1>>Cc1cn(CC(=O)O)c(C)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110269705A1,CCCOc1ccc(F)c2c(=O)c(-c3ccc(OC)cc3)c[nH]c12.CN1CCNCC1.[NH-]CC(Cl)C(=O)O>>CCCOc1ccc(F)c2c(=O)c(-c3ccc(OC)cc3)c[nH]c12.CN1CCN(C(C[NH-])C(=O)O)CC1,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US04548944,CNc1cccc(C(=O)CBr)c1.N=C(N)NC(N)=S>>CNc1cccc(-c2csc(NC(=N)N)n2)c1,,CCO,,Br,,test
US05948786,CC(C)(C)OC(=O)NCCCCCCC(=O)N1CCC(c2nc(N)nc3ccccc23)CC1>>NCCCCCCC(=O)N1CCC(c2nc(N)nc3ccccc23)CC1,,C1CCOC1,,C1COCCO1,Cl,test
US20060211720A1,CCOc1cc(/C=N/c2ccc(C#N)cc2)c(F)c(OC(C)C)c1.c1ccc(-c2ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c2-c2ccccc2)cc1>>CCOc1cc(CN(c2ccc(C#N)cc2)c2nc(-c3ccccc3)c(-c3ccccc3)n2C(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)c(OC(C)C)c1,,C1CCOC1,,[Li]CCCC,,test
US20120289522A1,Br[Mg]CCCc1ccccc1.Cc1noc(-c2ccc(Br)cc2)c1C=O>>Cc1noc(-c2ccc(Br)cc2)c1C(O)CCCc1ccccc1,,CCO,,,,test
US06441017B1,CC(C)(C)OC(=O)N[C@@H]1CCN(c2cccc3ccc(O[Si](C)(C)C(C)(C)C)cc23)C1=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)OC(=O)N[C@@H]1CCN(c2cccc3ccc(O[Si](C)(C)C(C)(C)C)cc23)C1=S,,Cc1ccccc1,,,,test
US20060094767A1,CC(C)(C)OC(=O)N1CCC2(CC1)CO2.O=[N+]([O-])c1c[nH]c([N+](=O)[O-])n1>>CC(C)(C)OC(=O)N1CCC2(CC1)Cn1cc([N+](=O)[O-])nc1O2,,CCO,,CC(=O)[O-].[Na+],,test
US20080004252A1,NC(=S)CN1C2CCC1CC(Oc1ccc(Cl)c(Cl)c1)C2.O=CCCl>>Clc1ccc(OC2CC3CCC(C2)N3Cc2nccs2)cc1Cl,,CC(=O)O,O,,,test
US20060173058A1,COC(=O)c1ccc(NCc2ccc(C#CCO)cc2)cc1O>>O=C(O)c1ccc(NCc2ccc(C#CCO)cc2)cc1O,,C1CCOC1,O,[Li+].[OH-],,test
US20160159782A1,CC(=O)C1CCC2(CC1)OCCO2.O=P(Cl)(Oc1ccccc1)Oc1ccccc1>>C=C(OP(=O)(Oc1ccccc1)Oc1ccccc1)C1CCC2(CC1)OCCO2,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05169868,C#CCNC.CC(C)Br.Cl>>C#CCN(C)C(C)C.Cl,,CCO,,,,test
US20060257987A1,CCCC(CCO)Oc1ccc2c(-c3ccccc3)coc2c1.CS(=O)(=O)Cl>>CCCC(CCOS(C)(=O)=O)Oc1ccc2c(-c3ccccc3)coc2c1,,ClCCl,,,,test
US05869485,N#CCC#N.O=C(CCl)c1ccccc1Nc1ccccc1>>N#Cc1c(-c2ccccc2Cl)cn(-c2ccccc2)c1N,,CCO,,CC(C)(C)[O-].[K+],,test
US05773607,CN(C)C=Nc1c(C(=O)CN)ncn1[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F>>O=C1CNC=Nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F,,CO,,C[O-].[Na+],,test
US20070049618A1,CCOc1cc(Nc2cccc(C(=O)OC)c2C(=O)OC)ccc1OC>>CCOc1cc(Nc2cccc(C(=O)O)c2C(=O)O)ccc1OC,,CCO,,[Na+].[OH-],,test
US20050148796A1,COC(=O)CC[C@H](O)c1ccc(NS(C)(=O)=O)cc1>>CS(=O)(=O)Nc1ccc([C@@H]2CCC(=O)O2)cc1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20040116518A1,CCOC(=O)/C=C/c1ccc(O)c(C(F)(F)F)c1C(F)(F)F.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)/C=C/c1ccc(S(=O)(=O)C(F)(F)F)c(C(F)(F)F)c1C(F)(F)F,,CCOCC,,c1ccncc1,,test
US20140371201A1,CCOC(=O)/C=C/c1cc(SCc2ccccc2)ccc1Nc1cc(Cl)c(Br)cc1OC>>COc1cc(Br)c(Cl)cc1-n1c(=O)ccc2cc(SCc3ccccc3)ccc21,,CO,,C[O-].[Na+],,test
US20070249674A1,Cc1cc(NC(=O)CCN2CCC(OC(=O)Nc3ccccc3-c3ccccc3)CC2)c(C)cc1C=NC[C@H](O[Si](C)(C)C(C)(C)C)c1ccc(O)c(NC=O)c1>>Cc1cc(NC(=O)CCN2CCC(OC(=O)Nc3ccccc3-c3ccccc3)CC2)c(C)cc1CNC[C@H](O[Si](C)(C)C(C)(C)C)c1ccc(O)c(NC=O)c1,,CC1CCCO1,,,,test
US04800224,C=Cc1ccc([C@@H](N)Cc2ccccc2)cc1.Cc1cccc(C=O)n1>>C=Cc1ccc([C@H](Cc2ccccc2)N=Cc2cccc(C)n2)cc1,,c1ccccc1,,,,test
US20090192162A1,CCOC(=O)COc1ccc(Sc2cc(C#CCOC)cc(OCCCN3CCOCC3)c2)cc1Cl>>COCC#Cc1cc(OCCCN2CCOCC2)cc(Sc2ccc(OCC(=O)O)c(Cl)c2)c1,,CCO,,Cl,[Na+].[OH-],test
US20130210844A1,O=[N+]([O-])c1cccc2c(Cl)ccnc12.Oc1ccc(C(F)(F)F)cc1>>O=[N+]([O-])c1cccc2c(Oc3ccc(C(F)(F)F)cc3)ccnc12,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090270374A1,Clc1cc(Cl)c(Cl)nn1.OCCS>>OCCSc1cc(Cl)nnc1Cl,,C1CCOC1,CCN(CC)CC,ClCCl,O=C([O-])O.[Na+],test
US20140094459A1,CC(C)(C)OC(=O)N1CCC[C@@H](n2nc(I)c3c(N)ncnc32)C1.CC1(C)OB(c2ccc(Oc3cccc(F)c3)cc2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4cccc(F)c4)cc3)c3c(N)ncnc32)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20150175557A1,CC1(C)CC(N)CCC1O.O=C(Cl)OCc1ccccc1>>CC1(C)CC(NC(=O)OCc2ccccc2)CCC1O,,C1CCOC1,CO,ClCCl,O=C([O-])[O-].[Na+].[Na+],test
US20120316151A1,NNC(=O)C[C@@H]1CCN(C(=O)C2CC2)C1.O=C=Nc1c(F)cc(Br)cc1F>>O=C(C[C@@H]1CCN(C(=O)C2CC2)C1)NNC(=O)Nc1c(F)cc(Br)cc1F,,ClCCl,,,,test
US20050245741A1,CC(=O)OC(C)=O.COC(=O)c1ccc([N+](=O)[O-])c(O)c1>>COC(=O)c1ccc(NC(C)=O)c(O)c1,[Pd],C1CCOC1,,O,[H][H],test
US06350749B1,CS(=O)(=O)Cl.Cc1c[nH]c2c1C(=O)CC(c1cccs1)C2>>Cc1cn(S(C)(=O)=O)c2c1C(=O)CC(c1cccs1)C2,,CN(C)C=O,,[H-].[Na+],,test
US05969190,CCOC(=O)C=CC[C@@H](C)CCC1OC1(C)C>>CCOC(=O)CCC[C@@H](C)CCC1OC1(C)C,[Pd],CCOC(C)=O,,,,test
US05190958,CC(C)(C)c1ccc(CC2CN(Cc3ccccc3)CCO2)cc1.CC(Cl)OC(=O)Cl>>CC(C)(C)c1ccc(CC2OCCN(Cc3ccccc3)C2=O)cc1,,ClCCCl,,,,test
US06384058B1,C=C(O[Si](C)(C)C)c1ccc2ccccc2c1.O=C(C=Cc1ccc2c(c1)OCO2)c1ccccc1O>>O=C(CC(CC(=O)c1ccccc1O)c1ccc2c(c1)OCO2)c1ccc2ccccc2c1,,CS(C)=O,,[Cs+].[F-],,test
US07790709B2,CN(C)C=O.Cc1csc2ccc(F)cc12>>CNCc1sc2ccc(F)cc2c1C,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US04863942,CCCc1c(OCCCOc2cc([N+](=O)[O-])c(Cl)cc2C)ccc(C(C)=O)c1O>>CCCc1c(OCCCOc2cc(N)c(Cl)cc2C)ccc(C(C)=O)c1O,[Ni],C1CCOC1,,,,test
US04845118,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccnc(CSc2nc3cscc3[nH]2)c1>>COc1ccnc(CSc2nc3cscc3n2C(=O)OC(C)(C)C)c1,,CN(C)C=O,,CCN(CC)CC,,test
US20100173909A1,CCOC(=O)c1sc(N2CC[C@@H](NC(=O)c3[nH]c(C)c(Cl)c3Cl)[C@@H](OC)C2)nc1-c1cnc(NCC2CN3CCN2CC3)cn1>>CO[C@H]1CN(c2nc(-c3cnc(NCC4CN5CCN4CC5)cn3)c(C(=O)O)s2)CC[C@H]1NC(=O)c1[nH]c(C)c(Cl)c1Cl,,CO,O,[Li+].[OH-],,test
US20150025071A1,COc1ccccc1N1CCNCC1.CSc1nc2c(c(=O)[nH]1)CCCC2>>COc1ccccc1N1CCN(c2nc3c(c(=O)[nH]2)CCCC3)CC1,,CC(C)CCO,,,,test
US20110159019A1,COc1ccncc1CO.O=S(Cl)Cl>>COc1ccncc1CCl,,ClC(Cl)Cl,,,,test
US20080312231A1,CI.COC(=O)Cc1ccccc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1>>COC(=O)Cc1ccccc1N(C)S(=O)(=O)c1ccc(Cl)c(Cl)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090036492A1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.Cc1ccc2ccc(C)c(C=O)c2c1>>COc1cc(O)c2c(c1C(=O)NCc1c(C)ccc3ccc(C)cc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20150329849A1,CCOC(=O)CBr.CN(C)CCOCCO>>CCOC(=O)C[N+](C)(C)CCOCCO.[Br-],,ClCCl,,,,test
US20130274255A1,COc1ccc(-c2nn(COCC[Si](C)(C)C)c3c2Cc2sc(-c4ccc(OC)c(OC)c4)cc2-3)cc1>>COc1ccc(-c2n[nH]c3c2Cc2sc(-c4ccc(OC)c(OC)c4)cc2-3)cc1,,CO,,Cl,,test
US20130059834A1,Cn1nc(-c2cnc3c(n2)c(C(=O)NCC2CC2)cn3COCC[Si](C)(C)C)c2ccc(Cl)cc21>>Cn1nc(-c2cnc3[nH]cc(C(=O)NCC4CC4)c3n2)c2ccc(Cl)cc21,,ClCCl,,NCCN,O=C(O)C(F)(F)F,test
US04758557,O=C(Sc1cccnc1)c1ccccc1.OCCI>>CC(O)[n+]1cccc(SC(=O)c2ccccc2)c1.[I-],,CC(C)=O,,,,test
US20080076762A1,CCCCCc1cccs1.O=C=O>>CCCCCc1ccc(C(=O)O)s1,,CCOCC,O,Cl,[Li]CCCC,test
US20050239841A1,COc1ccc([C@@]23CC[C@@H](N)C[C@@H]2N(C)CC3)cc1OC.Nc1ccc(C(F)(F)F)nc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc([C@@]23CC[C@@H](NC(=O)Nc4ccc(C(F)(F)F)nc4)C[C@@H]2N(C)CC3)cc1OC,,ClCCl,,CCN(CC)CC,,test
US20110269774A1,CN(C)Cc1cc(N)n(C)n1.CNC(=O)c1cccc(F)c1Nc1cc(Cl)ncc1Cl>>CNC(=O)c1cccc(F)c1Nc1cc(Nc2cc(CN(C)C)nn2C)ncc1Cl,,C1COCCO1,,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20130150325A1,Cc1cc(C(F)S(=O)(=O)c2nc3ccccc3s2)nn1C1CCCCO1.O=Cc1ccc(OC(F)(F)F)c(F)c1>>Cc1cc(/C(F)=C/c2ccc(OC(F)(F)F)c(F)c2)nn1C1CCCCO1,,C1CCOC1,,[Cl-].[NH4+],C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US05232947,C=CCN(CC=C)C(=O)C(=O)OC>>C=CCN(CC=C)C(=O)C(=O)O,,CO,,[Na+].[OH-],,test
US20030114666A1,CC(=O)c1csc(Br)c1.NOCc1ccccc1>>CC(=NOCc1ccccc1)c1csc(Br)c1,,CO,,Cl,,test
US06387911B1,CCOC(=O)c1cc(OC)ccc1C#N>>COc1ccc(C#N)c(CO)c1,,C1CCOC1,,[BH4-].[Li+],,test
US20150175623A1,CCOC(=O)[C@@H](Cc1ccccc1O)OC(C)=O.COc1ccccc1-c1nccc(CO)n1>>COc1ccccc1-c1nccc(COc2ccccc2C[C@@H](O)C(=O)O)n1,,Cc1ccccc1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140179715A1,CC(C)(C)OC(=O)N1CCn2c1cc(OCc1ccc(Oc3cccc(C(F)(F)F)c3)c(C#N)c1)nc2=O>>N#Cc1cc(COc2cc3n(c(=O)n2)CCN3)ccc1Oc1cccc(C(F)(F)F)c1,,O=C(O)C(F)(F)F,,,,test
US20110230458A1,CC(C)(C)OC(=O)N1CC[C@H](NC(=O)OCc2ccccc2)[C@H](O)C1>>CC(C)(C)OC(=O)N1CC[C@H](N)[C@H](O)C1,[Pd],CO,,[H][H],,test
US20130217666A1,C#CC(C)(O)COC.NC(=O)c1nc2n(c1-c1nc(C3CC3)n[nH]1)CCOc1cc(F)c(Br)cc1-2>>COCC(C)(O)C#Cc1cc2c(cc1F)OCCn1c-2nc(C(N)=O)c1-c1nc(C2CC2)n[nH]1,,CN(C)C=O,,CC(C)NC(C)C,,test
US05183492,CCOC(=O)C(C)(C)OC(=O)c1cc([N+](=O)[O-])c(F)cc1Cl>>CCOC(=O)C(C)(C)OC(=O)c1cc(N)c(F)cc1Cl,[Fe],CCO,,Cl,O,test
US20020099212A1,CCCCCS(N)(=O)=O.Cc1sc2ccc(C(=O)O)cc2c1Cc1ccc(Cl)cc1Cl>>CCCCCS(=O)(=O)NC(=O)c1ccc2sc(C)c(Cc3ccc(Cl)cc3Cl)c2c1,,CN(C)C=O,,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US20160024021A1,C[C@@H](O)Cn1cc([N+](=O)[O-])cn1>>C[C@@H](O)Cn1cc(N)cn1,[Pd],CO,,,,test
US20100204209A1,CN(C)C(=O)CC1CCC2(CC1)OCCO2>>CN(C)C(=O)CC1CCC(=O)CC1,,CC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20110098302A1,BrP(Br)Br.COC(=O)Cc1cccc(Oc2ccc(Br)cc2CO)c1>>COC(=O)Cc1cccc(Oc2ccc(Br)cc2CBr)c1,,COCCOC,,O=C([O-])O.[Na+],,test
US20160237090A1,C[C@H]1Cn2ncc(N3C(=O)OC[C@H]3c3ccccc3)c2CN1.O=C(Nc1cc(F)c(F)c(F)c1)Oc1ccccc1>>C[C@H]1Cn2ncc(N3C(=O)OC[C@H]3c3ccccc3)c2CN1C(=O)Nc1cc(F)c(F)c(F)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20060094696A1,CCc1cc2c(cc1OCc1ccccc1)CCC1C2CCC2(C)C(=CCOC)CCC12>>CCc1cc2c(cc1O)CCC1C2CCC2(C)C(=CCOC)CCC12,,CC(C)(C)O,,CC(C)O,,test
US06110903,CCn1c(C)nc2c([N+](=O)[O-])cccc21.O=C1CCC(=O)N1Br>>CCn1c(CBr)nc2c([N+](=O)[O-])cccc21,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20130079561A1,CC(=O)CO.OCC(O)CO>>CC(=O)CO.CC(O)CO,,O,,,,test
US20060128734A1,CN.Nc1ccc(Cc2cc(Cl)ncn2)cc1>>CNc1cc(Cc2ccc(N)cc2)ncn1,,CCO,,,,test
US20160024095A1,CC(C)(C)OC(=O)N1CCn2cc(CO)nc2C1>>OCc1cn2c(n1)CNCC2,,CCOC(C)=O,Cl,,,test
US20010036944A1,COC(=O)CBr.COC(=O)c1ccccc1S(=O)(=O)Nc1ccccc1C(F)(F)F>>COC(=O)CN(c1ccccc1C(F)(F)F)S(=O)(=O)c1ccccc1C(=O)OC,,CN(C)C=O,,[H-].[Na+],,test
US20050070549A1,CC(C)(C)OC(=O)N1CCC(NCc2ccc(Cl)cc2)CC1.CC=O>>CCN(Cc1ccc(Cl)cc1)C1CCNCC1,CC(=O)O,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150094297A1,BrCc1ccccc1.CC(=O)c1cc2c(O)cc(F)cc2o1>>CC(=O)c1cc2c(OCc3ccccc3)cc(F)cc2o1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050032786A1,N#Cc1cccc(Cl)n1.Sc1ccncc1>>N#Cc1cccc(Sc2ccncc2)n1,,C1CCOC1,O,CCOC(C)=O,[H-].[Na+],test
US20150315198A1,O=C1NC(=O)c2ccccc21.OCc1cc2ccc(Cl)nc2s1>>O=C1c2ccccc2C(=O)N1Cc1cc2ccc(Cl)nc2s1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06008220,NO.O=C(O)CCC(=O)c1ccc(N2CCC(c3ccccc3)CC2)cc1>>O=C(O)CC/C(=N/O)c1ccc(N2CCC(c3ccccc3)CC2)cc1,,CCO,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20020137931A1,N#Cc1ccc(B(O)O)cc1.Oc1ccc(Br)cc1F>>N#Cc1ccc(-c2ccc(O)c(F)c2)cc1,,CC(C)O,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US04880802,CN1CCNCC1.COc1cccc2c1CC(=O)CC2>>COc1cccc2c1CC(N1CCN(C)CC1)CC2,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20140134133A1,COc1ncc(-c2ccc3nncn3c2)cc1NS(=O)(=O)c1ccc(F)cc1F.O=C1CCC(=O)N1Br>>COc1ncc(-c2ccc3nnc(Br)n3c2)cc1NS(=O)(=O)c1ccc(F)cc1F,,ClC(Cl)Cl,,,,test
US20080287409A1,CC(=O)OC(C)=O.NCc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1ccc(-c2noc(=O)[nH]2)c(F)c1>>CC(=O)NCc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1ccc(-c2noc(=O)[nH]2)c(F)c1,,ClCCl,,O,c1ccncc1,test
US20070015918A1,CC(N)=NO.COC(=O)CC(=O)C1CC1>>Cc1noc(CC(=O)C2CC2)n1,,Cc1ccccc1,,,,test
US05518903,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(N)CC(=O)O>>CC(CC(=O)O)NC(=O)OC(C)(C)C,,O,,C1COCCO1,[Na+].[OH-],test
US06211223B1,COc1cc(C)c(Br)cc1S(=O)(=O)O>>COc1cc(C)ccc1S(=O)(=O)O,[Pd],CO,,O,O,test
US20040152743A1,Nc1ccc(-c2noc(=O)[nH]2)cc1OC(F)(F)F.O=C=NC(=O)c1cc(F)c(F)cc1Cl>>O=C(NC(=O)c1cc(F)c(F)cc1Cl)Nc1ccc(-c2noc(=O)[nH]2)cc1OC(F)(F)F,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20050215574A1,CC(C)(C)OC(=O)N1CC[C@@H](O)C1.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>CC(C)(C)OC(=O)N1CC[C@@H](OS(=O)(=O)c2ccc([N+](=O)[O-])cc2)C1,,ClCCl,,c1ccncc1,O=C([O-])O.[Na+],test
US20090048281A1,O=C(CBr)Nc1ccon1.O[C@H]1CN2CCC1CC2>>O=C(C[N+]12CCC(CC1)[C@@H](O)C2)Nc1ccon1.[Br-],,CC#N,ClC(Cl)Cl,,,test
US20160244535A1,CC(C)(Br)C(=O)Br.CC1(C)Cc2ccccc2C1>>CC1Cc2cc3c(cc2C1=O)CC(C)(C)C3,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20160060257A1,COc1ccc(F)cc1-c1ccnc2c1cc(C1=CC3CC4(CC3C1)OCCO4)n2S(=O)(=O)c1ccc(C)cc1>>COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CC4CC5(CC4C3)OCCO5)cc12,,CO,,[Na+].[OH-],,test
US20090324569A1,COc1ccc(C=O)cc1B(O)O.Ic1cccc(-c2nnco2)c1>>COc1ccc(C=O)cc1-c1cccc(-c2nnco2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,COCCOC,O=C([O-])[O-].[K+].[K+],,test
US05393730,Fc1c2ccc(c1F)C(Br)OCO2.[C-]#N>>N#CC1OCOc2ccc1c(F)c2F,,CCO,,O,,test
US20110172202A1,COC(=O)[C@@H](C)O.CS(=O)(=O)Cl>>COC(=O)[C@@H](C)OS(C)(=O)=O,,Cc1ccccc1,,,,test
US20100292196A1,CCn1ncc2c(NC3CCCCC3)c(C3=NOC4(CCC(C(=O)[O-])CC4)C3)cnc21>>CCn1ncc2c(NC3CCCCC3)c(C3=NOC4(CCC(C(=O)O)CC4)C3)cnc21,,C1CCOC1,O,[Li+].[OH-],,test
US05095014,CN.O=C(Cl)N1CC(Oc2ccc(F)cc2Cl)C1>>CNC(=O)N1CC(Oc2ccc(F)cc2Cl)C1,,C1CCOC1,O,,,test
US03932425,Cl.NC1CCC2(CCc3ccccc3C2)CC1.O=C(CCCCl)c1ccc(F)cc1>>Cl.O=C(CCCNC1CCC2(CCc3ccccc3C2)CC1)c1ccc(F)cc1,,CN(C)C=O,,[I-].[K+],,test
US20040225108A1,COC(=O)[C@@H](NC(=O)[C@H](CSCNC(C)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CSCNC(C)=O)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)O)[C@@H](C)O>>CC(=O)NCSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CSCNC(C)=O)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)O)C(=O)N[C@H](C(=O)O)[C@@H](C)O,,CCO,,CC(=O)O,[BH4-].[Na+],test
US20070060577A1,CCOC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(S(C)(=O)=O)ncc2c1=O.Nc1ccc(CN2CCOCC2)cc1>>CCOC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(Nc3ccc(CN4CCOCC4)cc3)ncc2c1=O,,CC(C)O,,,,test
US20160214997A1,CC(C)(C)OC(=O)N1CCCC(O)(C(F)(F)F)C1.Cl>>OC1(C(F)(F)F)CCC[NH2+]C1.[Cl-],,C1COCCO1,,ClCCl,,test
US20120202785A1,N#Cc1c(F)ccc([N+](=O)[O-])c1Nc1ccccn1>>N#Cc1c(F)ccc(N)c1Nc1ccccn1,[Fe],CO,O,[Cl-].[NH4+],,test
US20150252022A1,C1=COCCC1.Cc1[nH]ncc1Br>>Cc1c(Br)cnn1C1CCCCO1,O=C(O)C(F)(F)F,O,,CCOC(C)=O,,test
US20050010052A1,C#CCN(CC)C(=O)OC(C)(C)C.O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(I)ncc1Cl>>CCN(CC#Cc1cc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c(Cl)cn1)C(=O)OC(C)(C)C,[Cu]I,CC#N,,CCN(CC)CC,,test
US20040067964A1,CS(=O)(=O)c1ccc2[nH]c(C3=CCOCC3)cc2c1.Fc1ccc(CBr)cc1>>CS(=O)(=O)c1ccc2c(c1)cc(C1=CCOCC1)n2Cc1ccc(F)cc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20080312286A1,COC(=O)CCc1ccc(OCCCCOc2cc3c(c(Cl)c2Cl)C(=O)C(C)(C2CCCC2)C3)cc1>>CC1(C2CCCC2)Cc2cc(OCCCCOc3ccc(CCC(=O)O)cc3)c(Cl)c(Cl)c2C1=O,,C1CCOC1,,Cl,[Na+].[OH-],test
US20150038438A1,C=CCC(OCc1ccccc1)c1cc(Cl)ccc1C(O)C=C>>C=CCC(OCc1ccccc1)c1cc(Cl)ccc1C(=O)C=C,O=[Mn]=O,ClCCl,,,,test
US20090318442A1,CCOC(=O)CC(=O)c1ccccc1OC.O=C1CCC(=O)N1Br>>CCOC(=O)C(Br)C(=O)c1ccccc1OC,,ClC(Cl)(Cl)Cl,,O,,test
US20120149718A1,Cc1ccccc1CC(C(=O)O)c1ccc(S(C)(=O)=O)cc1.Nc1cnc(Br)cn1>>Cc1ccccc1CC(C(=O)Nc1cnc(Br)cn1)c1ccc(S(C)(=O)=O)cc1,CN(C)C=O,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20150291526A1,CC1(C)CCC(CC(=O)O)CC1.CC1(C)OC(=O)CC(=O)O1>>CC1(C)OC(=O)C(=C(O)CC2CCCCC2)C(=O)O1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20120071512A1,CCS(=O)(=O)NCc1cncc(Br)c1.CI>>CCS(=O)(=O)N(C)Cc1cncc(Br)c1,,CN(C)C=O,,[H-].[Na+],,test
US05082856,CCCCCCCCCCCCCc1cc(C(=O)OCC)c[nH]1>>CCCCCCCCCCCCCc1cc(C(=O)O)c[nH]1,,CCO,,[Na+].[OH-],,test
US20060293352A1,CCSc1ccc(C=O)cc1.FC(F)(F)c1ccc(OCc2ccccc2)c(Br)c1>>CCSc1ccc(C(O)c2cc(C(F)(F)F)ccc2OCc2ccccc2)cc1,,CCOCC,,[Li]CCCC,,test
US20120065396A1,COC(=O)c1cc(OC)c(OC)c(Br)c1CBr.COC(=O)c1ccc(CN)cc1>>COC(=O)c1ccc(CN2Cc3c(cc(OC)c(OC)c3Br)C2=O)cc1,,C1CCOC1,,CCN(CC)CC,Cl,test
US20050038072A1,COc1ccc(NS(C)(=O)=O)cc1CN1CCC(=O)C(C(c2ccccc2)c2ccccc2)C1.Cc1ccc(S(=O)(=O)OCC(F)(F)F)cc1>>COc1ccc(N(CC(F)(F)F)S(C)(=O)=O)cc1CN1CCC(=O)C(C(c2ccccc2)c2ccccc2)C1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20040058965A1,COC(=O)Cc1ccccc1O.COc1ccc(CO)cc1OCc1nc(-c2ccccc2)oc1OC>>COc1ccc(COc2ccccc2CC(=O)O)cc1OCc1nc(-c2ccccc2)oc1C,,C1CCOC1,Cc1ccccc1,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060116393A1,COc1ccc(CCNC=O)cc1Br>>COc1cc2c(cc1Br)CCN=C2,,ClCCl,,Cl,O=C(Cl)C(=O)Cl,test
US20080132525A1,COC(=O)[C@@H]1C[C@H](SC[C@H]2O[C@@H](n3cnc4c(-n5cnnc5)ncnc43)[C@@H]3OC(C)(C)O[C@@H]32)CN1C(=O)OC(C)(C)C.NCCCc1ccccc1>>COC(=O)[C@@H]1C[C@H](SC[C@H]2O[C@@H](n3cnc4c(NCCCc5ccccc5)ncnc43)[C@@H]3OC(C)(C)O[C@@H]32)CN1C(=O)OC(C)(C)C,,CN(C)C=O,,,,test
US05130239,OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)OC(O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O.OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O>>OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O[C@]3(CO)O[C@H](CO)[C@@H](O)[C@@H]3O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O,,O,,,,test
US20060270654A1,CC(=O)c1cccc(Br)n1.NO>>C/C(=N/O)c1cccc(Br)n1,,c1ccncc1,,Cl,,test
US05075304,CCOC(=O)C(=O)Nc1c([N+](=O)[O-])cc(Cl)cc1C(F)(F)F.CI>>CCOC(=O)C(=O)N(C)c1c([N+](=O)[O-])cc(Cl)cc1C(F)(F)F,,CN(C)C=O,,[H-].[Na+],,test
US20090069250A1,CC(=O)NCC(C(=O)O)c1ccc(C(=O)OC(C)(C)C)cc1.Nc1ccccc1>>CC(=O)NCC(C(=O)Nc1ccccc1)c1ccc(C(=O)OC(C)(C)C)cc1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20080076785A1,CC1CCNCC1.Cc1nc2ncnn2c(CBr)c1-c1c(F)cc(F)cc1F>>Cc1nc2ncnn2c(CN2CCC(C)CC2)c1-c1c(F)cc(F)cc1F,,ClCCl,,CCN(CC)CC,,test
US05102877,CC(OC1CCCCO1)C1CCN(C(=O)OC(C)(C)C)C1C>>CC(O)C1CCN(C(=O)OC(C)(C)C)C1C,,CC(=O)O,,Cl,,test
US20100210704A1,CCOC(=O)c1c(OCC)nn(-c2cc(SCC(F)(F)F)c(C)cc2F)c1N>>CCOC(=O)c1cn(-c2cc(SCC(F)(F)F)c(C)cc2F)nc1OCC,,C1CCOC1,,CC(C)(C)ON=O,,test
US05646173,C[C@@H](O)CN.Cc1ccc2c(c1)C(=O)C(CC=O)C21CCCCC1>>Cc1ccc2c(c1)-c1c(ccn1C[C@@H](C)O)C21CCCCC1,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,O,,test
US20150038488A1,CC(C)(C)n1cc(Br)cn1.CON(C)C(C)=O>>CC(=O)c1cnn(C(C)(C)C)c1,,C1CCOC1,,[Li]CCCC,,test
US04659503,CCCCCc1ccc(-c2cccs2)cn1.ClCl>>CCCCCc1ccc(-c2ccc(Cl)s2)cn1,,ClC(Cl)(Cl)Cl,,BrBr,,test
US04737487,CCCC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(N)=O)C(C)C>>CCCC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(N)=O)C(C)C,,O=C(O)C(F)(F)F,,Br,,test
US05750524,CCOC(=O)COc1ccc2c(c1)CC(CNC(=O)OC(C)(C)C)C2.O=S(=O)(Cl)c1ccccc1>>CCOC(=O)COc1ccc2c(c1)CC(CNS(=O)(=O)c1ccccc1)C2,,ClCCl,O,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US05380724,CC(C)(C)OC(=O)N1CCNCC1.ClCC1CO1>>CC(C)(C)OC(=O)N1CCN(CC2CO2)CC1,,CO,,,,test
US04929613,CCO.NO.O=C1CCC(c2cc3c(cc2F)c(=O)ccn3C2CC2)C1.[OH-]>>O=C(O)c1cn(C2CC2)c2cc(C3CCC(=NO)C3)c(F)cc2c1=O,,O,,Cl,,test
US20020022638A1,CCCCCCNC(=O)Nc1cccnc1Nc1ccc(CCNC[C@H](O)COc2ccc(O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)cc2)cc1>>CCCCCCNC(=O)Nc1cccnc1Nc1ccc(CCNC[C@H](O)COc2ccc(O)cc2)cc1,,CO,ClC(Cl)Cl,,,test
US20090082434A1,Cc1ccc(S(=O)(=O)OCC2Cc3cccc(Br)c3O2)cc1.OB(O)c1ccc(F)cc1F>>Cc1ccc(S(=O)(=O)OCC2Cc3cccc(-c4ccc(F)cc4F)c3O2)cc1,Cc1ccccc1[P](c1ccccc1C)(c1ccccc1C)[Pd](Cl)(Cl)[P](c1ccccc1C)(c1ccccc1C)c1ccccc1C,,,O=C([O-])[O-].[K+].[K+],,test
US20020119995A1,CCOC(=O)C(C(=O)OCC)=C1NC(C)=C(S(=O)(=O)NC)S1.Nc1ccc(-c2ccccc2)cc1>>CCOC(=O)C(C(=O)Nc1ccc(-c2ccccc2)cc1)=C1NC(C)=C(S(=O)(=O)NC)S1,,Cc1ccccc1C,,,,test
US20130196993A1,CSc1nc(N)cc(NCCNC(=O)OC(C)(C)C)n1.O=S(=O)(O)C(F)(F)F>>CSc1nc(N)cc(NCCN)n1.O=S(=O)(O)C(F)(F)F,,ClCCl,,,,test
US04119635,Br.Cn1nc(-c2ccccc2)nc1-c1ccccc1CO>>Cn1nc(-c2ccccc2)nc1-c1ccccc1CBr,,ClCCl,,,,test
US06060469,O=[N+]([O-])c1cc(Br)c(O)c(CCO)c1>>O=[N+]([O-])c1cc(Br)c2c(c1)CCO2,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090286811A1,COc1cccc(C=O)c1OCC1CC1.Cc1nc2n(C)c3ccccc3n2c(=O)c1-c1ccc(OC(F)(F)F)cc1>>COc1cccc(/C=C/c2nc3n(C)c4ccccc4n3c(=O)c2-c2ccc(OC(F)(F)F)cc2)c1OCC1CC1,,CCO,,C,C[O-].[Na+],test
US20060292060A1,CCOC(=O)CCCCCBr.Oc1ccc(I)cc1>>CCOC(=O)CCCCCOc1ccc(I)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05041673,CC(C)(C)OC(=O)NC1Cc2ccc3ccccc3c2CC1=O.Cl>>Cl.NC1Cc2ccc3ccccc3c2CC1=O,,CCOCC,,,,test
US20100113512A1,NC(=S)c1ccc(O)cc1.O=C(O)C(=O)CBr>>O=C(O)c1csc(-c2ccc(O)cc2)n1,,CO,O,Cl,[K+].[OH-],test
US20060069097A1,CI.c1cnn2ncc(-c3ccnc(NC4CC4)n3)c2c1>>CN(c1nccc(-c2cnn3ncccc23)n1)C1CC1,,CN(C)C=O,,[H-].[Na+],,test
US20070276011A1,COc1ccc(CO)cc1.O=Cc1ccc(O)c(C(=O)O)c1>>COc1ccc(COC(=O)c2cc(C=O)ccc2O)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130317003A1,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)/C=C/c1cn[nH]c1.Fc1cc(Cl)cc(OCCBr)c1>>CC(C)(C)OC(=O)Nc1ccccc1NC(=O)/C=C/c1cnn(CCOc2cc(F)cc(Cl)c2)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120157439A1,C/C(=C(\C#N)C(N)=O)N(C)C.CCOC(=O)CS>>CCOC(=O)c1sc(C)c(C(N)=O)c1N,,O,,CCO,O=C([O-])[O-].[K+].[K+],test
US20150065464A1,CS(=O)(=O)Cl.Nc1ccc(C(=O)NC2CCC(=Cc3cccc(Oc4ccc(C(F)(F)F)cn4)c3)CC2)cn1>>CS(=O)(=O)Nc1ccc(C(=O)NC2CCC(=Cc3cccc(Oc4ccc(C(F)(F)F)cn4)c3)CC2)cn1,,ClCCl,,CCN(CC)CC,,test
US07071175B1,CCOC(=O)C(C(=O)OCC)C(c1ccccc1)c1ccc(NC(=O)OC(C)(C)C)nc1>>CCOC(=O)C(C(=O)O)C(c1ccccc1)c1ccc(NC(=O)OC(C)(C)C)nc1,,CCO,ClCCl,[K+].[OH-],,test
US20090131336A1,O=C(O)c1cc(-c2ccco2)on1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Nc1cc(-c2ccco2)on1,,c1ccccc1,,O,,test
US20090143407A1,COC(=O)c1cnc(OCc2c(-c3ccccc3)noc2C)cn1>>Cc1onc(-c2ccccc2)c1COc1cnc(C(=O)O)cn1,,CCO,,[Na+].[OH-],,test
US20100197678A1,CI.Cc1cc(C(O)(c2ccc3c(cnn3-c3ccc(F)cc3)c2)C(F)(F)F)c[nH]c1=O>>Cc1cc(C(O)(c2ccc3c(cnn3-c3ccc(F)cc3)c2)C(F)(F)F)cn(C)c1=O,,CN(C)C=O,O,[H-].[Na+],,test
US20110105509A1,COC(=O)CBr.Cc1[nH]c2ccc(Cl)cc2c1Cc1nn(Cc2ccccc2)c(=O)c2ccccc12>>COC(=O)Cn1c(C)c(Cc2nn(Cc3ccccc3)c(=O)c3ccccc23)c2cc(Cl)ccc21,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04472400,C=CCn1c(NN)nc2ccccc2c1=O.O=C(Cl)CCCl>>C=CCn1c(NNC(=O)CCCl)nc2ccccc2c1=O,,ClC(Cl)Cl,,O,O=C([O-])[O-].[K+].[K+],test
US20140371209A1,COc1ccc2cc(C(O)C(F)(F)F)ccc2c1.CS(=O)(=O)Cl>>COc1ccc2cc(C(OS(C)(=O)=O)C(F)(F)F)ccc2c1,,ClCCl,,,,test
US20060111375A1,COc1cc2nccc(Cl)c2cc1OC.O=C(O)c1nc2ncccc2cc1O>>COc1cc2nccc(Oc3cnc4ncccc4c3)c2cc1OC,CN(C)c1ccncc1,Clc1ccccc1Cl,,O,,test
US20160194302A1,CCC1CCN(NC)CC1.CCOC(=O)Cn1ccnc1CCC(=O)O>>CCOC(=O)Cn1ccnc1CCC(=O)N1CCC(N(C)CC)CC1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04451476,COC(=O)CCc1cc(C)on1>>Cc1cc(CCCO)no1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20060258672A1,COC(=C1CC2CCC(C1)N2c1ncccn1)c1ccc(Br)cc1>>O=C(c1ccc(Br)cc1)C1CC2CCC(C1)N2c1ncccn1,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20090291971A1,OB(O)c1ccccc1.c1ccc2c(-n3nnc4ccccc43)ncnc2c1>>c1ccc(Oc2ncnc3ccccc23)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070105943A1,O=C(NCc1ccc(Br)o1)c1ccc2ncccc2c1.OB(O)c1ccccc1>>O=C(NCc1ccc(-c2ccccc2)o1)c1ccc2ccccc2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US20100099728A1,NC(CN1C(=O)C2(COc3cc4c(cc32)OCO4)c2c(Cl)cccc21)=NO.O=C(Cl)C1CC1>>NC(CN1C(=O)C2(COc3cc4c(cc32)OCO4)c2c(Cl)cccc21)=NOC(=O)C1CC1,,ClCCl,,CC(C)NC(C)C,,test
US20040029932A1,Brc1ccc2c(c1)CCO2.C=C(C)CC(O)(C(=O)OCC)C(F)(F)F>>CCOC(=O)C(O)(CC(C)(C)c1cc(Br)cc2c1OCC2)C(F)(F)F,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US04847251,O=C1CCC(c2ccc(-n3ccnc3)nc2)=NN1>>O=c1ccc(-c2ccc(-n3ccnc3)nc2)n[nH]1,,C1COCCO1,,,,test
US05977027,CC(C)(N)C(=O)O.O=C(Cl)C(Br)c1ccccc1>>CC(C)(NC(=O)C(Br)c1ccccc1)C(=O)O,,CC#N,,[NH4+].[OH-],,test
US20120330012A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=C(OCc1ccccc1)N1CCCC(c2ncn3cnc4[nH]ccc4c23)C1>>Cc1ccc(S(=O)(=O)n2ccc3c2ncn2cnc(C4CCCN(C(=O)OCc5ccccc5)C4)c32)cc1,,C1CCOC1,,[H-].[Na+],,test
US20150018377A1,O=[N+]([O-])c1ccc(F)cc1.Oc1cc(F)cc(Cl)c1>>O=[N+]([O-])c1ccc(Oc2cc(F)cc(Cl)c2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080255197A1,Cc1cnc(CN(Cc2ncccc2C(C)C)C2CCNCC2)c(C)c1.Nc1cccnn1.O=C(n1ccnc1)n1ccnc1>>Cc1cnc(CN(Cc2ncccc2C(C)C)C2CCN(C(=O)Nc3cccnn3)CC2)c(C)c1,,ClCCl,,,,test
US20130085131A1,COc1c(CN2CCN(C(=O)OC(C)(C)C)CC2)c([C@H](C)N)nc2ccc(F)cc12.N#Cc1c(N)ncnc1Cl>>COc1c(CN2CCN(C(=O)OC(C)(C)C)CC2)c([C@H](C)Nc2ncnc(N)c2C#N)nc2ccc(F)cc12,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20130252941A1,C[Si](C)(C)Br.N#Cc1cccc(F)c1-n1cc2c(Cl)ncc(F)c2n1>>N#Cc1cccc(F)c1-n1cc2c(Br)ncc(F)c2n1,,CCC#N,,,,test
US20140249133A1,C=C(OCC)c1cc(F)c(Cn2nc(-c3ncc(OC)c(Nc4ccncc4)n3)c3ccccc32)c(F)c1>>COc1cnc(-c2nn(Cc3c(F)cc(C(C)=O)cc3F)c3ccccc23)nc1Nc1ccncc1,,CCO,O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120071523A1,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21.COc1ccc(C(=O)c2coc3c(Br)cc(O)c(Br)c23)cc1>>COc1ccc(C(=O)c2coc3c2C(=O)C(=O)C=C3Br)cc1,,CS(C)=O,,,,test
US20100210594A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCNc1ccc(I)nn1>>CC(C)(C)OC(=O)NCCNc1ccc(I)nn1,,C1CCOC1,,,,test
US04943578,NCC(=O)N[C@H](CO)C(=O)O>>O=C1CNC(=O)[C@@H](CO)N1,,CO,,O=S(Cl)Cl,,test
US20130230542A1,CNc1ccccc1.OCCI>>CN(CCO)c1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20040029862A1,O=C1C2CCC1Cc1cc(O)ccc1C2.OCCN1CCOCC1>>O=C1C2CCC1Cc1cc(OCCN3CCOCC3)ccc1C2,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070066618A1,Cc1cc(C)c(N)c(Nc2ccc(CCCl)cc2)n1.O=C(O)CCc1nccs1>>Cc1cc(C)c2nc(CCc3nccs3)n(-c3ccc(CCCl)cc3)c2n1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20150266867A1,CN.O=Cc1cnn(C[C@H]2NC(=O)[C@H]2NC(=O)OCc2ccccc2)n1>>CNCc1cnn(C[C@H]2NC(=O)[C@H]2NC(=O)OCc2ccccc2)n1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100076027A1,N#Cc1ccc(OCC(c2c3c(nn2-c2ccc(Cl)cc2)CCCC3)C2CCCCC2)c(F)c1.[N-]=[N+]=[N-]>>Fc1cc(-c2nnn[nH]2)ccc1OCC(c1c2c(nn1-c1ccc(Cl)cc1)CCCC2)C1CCCCC1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20090143371A1,CN(C)C=O.Clc1ccc(Br)nc1>>O=Cc1ccc(Cl)cn1,,C1CCOC1,,,,test
US05610293,NC(=O)C(N)Cc1ccccc1>>NCC(N)Cc1ccccc1,,C1CCOC1,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20070281933A1,CC(C)(C)O.N#Cc1cc(Br)cc2c(C3CCN(C(=O)[O-])CC3)n[nH]c12>>CC(C)(C)OC(=O)N1CCC(c2n[nH]c3c(C(N)=O)cc(Br)cc23)CC1,,CC(C)(C)O,,[K+].[OH-],,test
US20060041128A1,CC(C)(C)OC(=O)NCCC=O.Cc1noc2nc(C(N)C(C)C)n(Cc3ccccc3)c(=O)c12>>Cc1noc2nc(C(NCCCNC(=O)OC(C)(C)C)C(C)C)n(Cc3ccccc3)c(=O)c12,CC(=O)O,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100048582A1,CN1CCN(c2cc(N)ccn2)CC1.O=S(=O)(Cl)c1cccc(OC(F)F)c1>>CN1CCN(c2cc(NS(=O)(=O)c3cccc(OC(F)F)c3)ccn2)CC1,,c1ccncc1,,,,test
US20100160387A1,COC(=O)Cc1cc(OC(F)F)c(OC)cc1Br>>COc1cc(Br)c(CC(=O)O)cc1OC(F)F,,CO,O,Cl,[Li+].[OH-],test
US20150243909A1,CC(C)c1ccccc1N.c1ccc(-c2nnc(-c3ccccc3-c3ccccc3)o2)cc1>>CC(C)c1ccccc1-n1c(-c2ccccc2)nnc1-c1ccccc1-c1ccccc1,,CN1CCCC1=O,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20130225679A1,CN(C)CC1CCC2CC2C1=O.Oc1cccc(Br)c1>>CN(C)CC1CCC2CC2C1(O)c1cccc(O)c1,,C1CCOC1,,[Li]C(C)(C)C,,test
US20060106048A1,CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)OC)c(N)c1)=NC(C)(C)C2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)OC)c(NC(=O)C(F)(F)F)c1)=NC(C)(C)C2,,C1CCOC1,,CCN(CC)CC,,test
US20110021537A1,CC(C)(C)OC(=O)CC[C@H](NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1)C(=O)O.CCOC(=O)N1CCN[C@H](C)C1>>CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)O)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)NC3CCC3)n(-c3ccccc3)n2)[C@H](C)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110034416A1,O=C(Nc1ccc(Oc2ccnc(N=C(c3ccccc3)c3ccccc3)c2Cl)c(F)c1)c1c[nH]cc(-c2ccc(F)cc2)c1=O>>O=C(Nc1ccc(Oc2ccnc(NC(c3ccccc3)c3ccccc3)c2Cl)c(F)c1)c1c[nH]cc(-c2ccc(F)cc2)c1=O,,C1CCOC1,CCO,[BH4-].[Na+],,test
US05066577,CC(=O)Nc1cc(Cl)c([N+](=O)[O-])cc1C#N.COCCOCCO>>COCCOCCOc1cc(N)c(C#N)cc1[N+](=O)[O-],,O,,[K+].[OH-],,test
US20150376188A1,COc1ccc(-c2n[nH]c3ncnc(N)c23)cc1[N+](=O)[O-].C[C@@H](O)c1oc2cccc(F)c2c(=O)c1-c1cccc(F)c1>>COc1ccc(-c2nn([C@@H](C)c3oc4cccc(F)c4c(=O)c3-c3cccc(F)c3)c3ncnc(N)c23)cc1[N+](=O)[O-],,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120289474A1,CCCOC/C(N)=N/O.COC(=O)C(=O)Cl>>CCCOCc1noc(C(=O)OC)n1,,C1CCOC1,,,,test
US20150266881A1,COC(=O)c1ccc([C@@H]2C[C@H]2N)cc1.O=C1CCS(=O)(=O)CC1>>COC(=O)c1ccc([C@@H]2C[C@H]2NC2CCS(=O)(=O)CC2)cc1,,CC(=O)O,CO,Cl,O=C([O-])O.[Na+],test
US20120220572A1,CC(C)(C)OC(=O)Nc1ccc(N)cc1.CS(=O)c1ncc2c(=O)n(-c3ccccc3Cl)c3nccn3c2n1>>CC(C)(C)OC(=O)Nc1ccc(Nc2ncc3c(=O)n(-c4ccccc4Cl)c4nccn4c3n2)cc1,,CCOC(C)=O,,,,test
US04933458,CCN(CC)c1ccccc1CSc1nc2ccccc2nc1C.O=C(OO)c1cccc(Cl)c1>>CCN(CC)c1ccccc1CS(=O)c1nc2ccccc2nc1C,,ClC(Cl)Cl,,,,test
US20040097526A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc2[nH]nnc2c1>>Cc1ccc2c(c1)nnn2C(=O)OC(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20120258949A1,NOC1CCCCO1.O=C(O)/C=C/c1ccc2c(c1)C(=O)NC1(CCCN(Cc3ccccc3)C1)O2>>O=C(/C=C/c1ccc2c(c1)C(=O)NC1(CCCN(Cc3ccccc3)C1)O2)NOC1CCCCO1,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US04847256,CCOC(=O)c1cn[nH]c1N.COC(CC(OC)OC)OC>>CCOC(=O)c1cnn2cccnc12,,CC(=O)O,,,,test
US20040087659A1,COc1cc(C(=O)O)c(N)cc1[N+](=O)[O-].O=C(Cl)Cl>>COc1cc2c(=O)oc(=O)[nH]c2cc1[N+](=O)[O-],,C1CCOC1,ClC(Cl)Cl,,,test
US03959309,Cc1cc(C)c2[nH]c3c(c2c1)CC(N(C)C)CC3>>Cc1cc(C)c2[nH]c3c(c2c1)CC(N(C)C)CC3,,CCOCC,,Cl,Cl,test
US20110263556A1,COc1ccc([N+](=O)[O-])cc1C(=O)O.Nc1ccc(Br)cc1>>COc1ccc([N+](=O)[O-])cc1C(=O)Nc1ccc(Br)cc1,,C1CCOC1,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US04016166,C=CCBr.O=c1[nH]c(=O)n(-c2cccc([N+](=O)[O-])c2)c2ccccc12>>C=CCn1c(=O)c2ccccc2n(-c2cccc([N+](=O)[O-])c2)c1=O,,O,,CN(C)C=O,[H-].[Na+],test
US20070281934A1,COC(=O)c1ccc2ccn(Cc3cccc([N+](=O)[O-])c3)c2c1>>COC(=O)c1ccc2ccn(Cc3cccc(N)c3)c2c1,[Zn],CC(=O)O,CO,,,test
US20070299050A1,COC(=O)c1cc(C)c2c(c1)S(=O)Cc1cc([N+](=O)[O-])cc(Cl)c1O2>>COC(=O)c1cc(C)c2c(c1)S(=O)Cc1cc(N)cc(Cl)c1O2,[Ni],CN(C)C=O,,,,test
US20030220358A1,CCCn1c(=O)[nH]c(=S)c2[nH]c(C34CCC(CCC(=O)OC)(CC3)CC4)nc21.CI>>CCCn1c(=O)nc(SC)c2[nH]c(C34CCC(CCC(=O)OC)(CC3)CC4)nc21,,CCO,O,[Na+].[OH-],,test
US20110311447A1,Nc1cccc2c1CC=CC2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1cccc2c1CC=CC2)C(F)(F)F,,ClCCl,,CCN(CC)CC,Cl,test
US20140275030A1,C=Cc1nc2ccc(-c3c(C)noc3C)c3c2n1[C@@H](c1ccccn1)CO3.O=[Os](=O)(=O)=O>>Cc1noc(C)c1-c1ccc2nc(C=O)n3c2c1OC[C@@H]3c1ccccn1,O=[Os](=O)(=O)=O,C1CCOC1,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20120184553A1,COC(=O)c1cc(O)ccc1O.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1cc(OS(=O)(=O)c2ccc(C)cc2)ccc1O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100137317A1,CC1(C)OB(c2ccc(OCc3ccc4ccccc4n3)cc2)OC1(C)C.CN1C(=O)C(Br)=C(N2CCC(=O)CC2)C1=O>>CN1C(=O)C(c2ccc(OCc3ccc4ccccc4n3)cc2)=C(N2CCC(=O)CC2)C1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US06166006,C1CCNCC1.O=[N+]([O-])c1cccc(CCl)c1>>O=[N+]([O-])c1cccc(CN2CCCCC2)c1,,C1CCOC1,,O,,test
US04624955,CCn1ncc2c(Cl)c(C(=O)c3cccc(F)c3)cnc21.NO>>CCn1ncc2c3noc(-c4cccc(F)c4)c3cnc21,,CC(=O)O,,Cl,Cl,test
US20070010670A1,O=C(Cl)c1ccc(O)c(C(F)(F)F)c1.c1ccc2c(c1)NCCO2>>O=C(c1ccc(O)c(C(F)(F)F)c1)N1CCOc2ccccc21,,CCOC(C)=O,,,,test
US20150239842A1,COC(=O)c1cc(C#N)cc(-c2c(C)cnn2C)c1C>>Cc1cnn(C)c1-c1cc(C#N)cc(C(=O)O)c1C,,CO,,Cl,[K+].[OH-],test
US20020082280A1,CCC(=O)Nc1ccc(C(=O)[O-])c(CC)c1N.Fc1ccc(COc2ccc(CBr)cc2)cc1>>CCOC(=O)c1ccc2nc(CC)n(Cc3ccc(OCc4ccc(F)cc4)cc3)c2c1,,O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20150133422A1,O=C(OCc1ccccc1)[C@@H]1C[C@@H](n2cc(-c3cn(S(=O)(=O)c4ccccc4)c4cc(F)ccc34)cn2)C1>>O=C(O)[C@@H]1C[C@@H](n2cc(-c3cn(S(=O)(=O)c4ccccc4)c4cc(F)ccc34)cn2)C1,[Pd],CO,,,,test
US20050032786A1,Fc1ccc(N2CCNCC2)cc1.N#Cc1ccnc(Cl)c1>>N#Cc1ccnc(N2CCN(c3ccc(F)cc3)CC2)c1,,CN1CCCC1=O,,O,,test
US04558132,CNc1ccccc1.Cl.O=[N+]([O-])c1cccnc1Cl>>CN(c1ccccc1)c1ncccc1[N+](=O)[O-].Cl,,Cl,,,,test
US20030212111A1,CCNc1ccc(C(C)=O)cc1N=C1SC(=C2Sc3ccccc3N2C)C(=O)N1Cc1ccccc1.NO>>CCNc1ccc(C(C)=NO)cc1N=C1SC(=C2Sc3ccccc3N2C)C(=O)N1Cc1ccccc1,,c1ccncc1,,Cl,,test
US20110319394A1,CNc1ncccc1N.O=C(n1ccnc1)n1ccnc1>>Cn1c(=O)[nH]c2cccnc21,,C1CCOC1,,,,test
US04108997,COc1ccc(-c2ncccc2O)cc1OC>>COc1ccc([C@@H]2NCCC[C@@H]2O)cc1OC,[Ni],C1COCCO1,,[Na+].[OH-],,test
US06822074B1,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@@H]2NC(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H](CC(=O)OCc3ccccc3)NC(=O)CNC2=O)c(C)c2c1OC(C)(C)C2>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@@H]2NC(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H](CC(=O)O)NC(=O)CNC2=O)c(C)c2c1OC(C)(C)C2,[Pd],C1CCOC1,,[H][H],,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4cccs4)nc(Cl)c3n2)cc1.Nc1cccc(S(=O)(=O)C(F)(F)F)c1>>O=S(=O)(c1cccc(Nc2nc(-c3cccs3)nc3cn[nH]c23)c1)C(F)(F)F,C1COCCO1,CO,,Cl,,test
US20040029902A1,O=C1COc2cccnc2N1.O=[N+]([O-])O>>O=C1COc2ccc([N+](=O)[O-])nc2N1,,CC(=O)O,CC(=O)OC(C)=O,,,test
US20120208817A1,CCO.NC(N)=O.O=C(Cc1ccccc1)c1ccccc1.O=Cc1ccc(C(=O)O)c([N+](=O)[O-])c1>>CCOC(=O)c1ccc(C2NC(=O)NC(c3ccccc3)=C2c2ccccc2)cc1[N+](=O)[O-],,CCOC(C)=O,,Cl,,test
US08394825B2,COc1cc2c(cc1OCc1ccccc1)CC(C)NC2.COc1cccc(CCl)c1>>COc1cccc(CN2Cc3cc(OC)c(OCc4ccccc4)cc3CC2C)c1,,CCO,,,,test
US20120203002A1,Nc1ncc(-c2cnn(CCO)c2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12.O=C(O)/C=C\C(=O)O>>Nc1ncc(-c2cnn(CCO)c2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12.O=C(O)/C=C\C(=O)O,,CN(C)C=O,,,,test
US20100093803A1,CC(C)(C)OC(=O)c1ccc(NN)nc1.CCOC(=O)/C(=C\N(C)C)c1cncc(Br)c1.Cl>>CC(C)(C)OC(=O)c1ccc(-n2[nH]cc(-c3cncc(Br)c3)c2=O)nc1.Cl,,C1COCCO1,CCO,Cc1ccc(S(=O)(=O)O)cc1,,test
US05723452,Cc1cc(C)cc(S)c1.N#Cc1c([N+](=O)[O-])cccc1[N+](=O)[O-]>>Cc1cc(C)cc(Sc2cccc([N+](=O)[O-])c2C#N)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US06245761B1,Cn1c(COc2ccc(Cl)cc2)cc2ccccc21.O=C(Cl)C(=O)Cl>>Cn1c(COc2ccc(Cl)cc2)c(C(=O)C(=O)Cl)c2ccccc21,,CCOCC,,,,test
US20160046596A1,CCc1cc(C=O)c(OCOC)c(-c2ccccc2)n1>>CCc1cc(C=O)c(O)c(-c2ccccc2)n1,,C1CCOC1,,Cl,O=C([O-])[O-].[K+].[K+],test
US07947727B2,OC(COCc1ccccc1)(COCc1ccccc1)C(F)(F)F>>OCC(O)(CO)C(F)(F)F,[Pd],Cc1ccccc1,,CCO,,test
US20110207716A1,CSc1ccc(C2=NCCN2)cc1>>CSc1ccc(-c2ncc[nH]2)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160108027A1,COc1cc(C(=O)N2CC(C)OCC2CCO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc2nc(NCc3cc(Cl)ccn3)oc12>>COc1cc(C(=O)N2CC(C)OCC2CCO)cc2nc(NCc3cc(Cl)ccn3)oc12,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20070167631A1,CCCCC([Sn])=C(CCCC)CCCC.CCOC(=O)c1ncc(C(F)(F)F)cc1Cl>>C=Cc1nc(C(=O)OCC)ccc1C(F)(F)F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20100035883A1,CNC.O=Cc1cccc(C2Nc3cccc4c(=O)[nH]nc(c34)C2c2ccccc2)c1>>CN(C)Cc1cccc(C2Nc3cccc4c(=O)[nH]nc(c34)C2c2ccccc2)c1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20110003807A1,CCOC(=O)CC(=O)C1CCOCC1.O=S(=O)(Cl)Cl>>CCOC(=O)C(Cl)C(=O)C1CCOCC1,,CCOCC,,,,test
US20090042929A1,NCc1cccs1.O=C=NC12CC3CC(CC(C3)C1)C2>>O=C(NCc1cccs1)NC12CC3CC(CC(C3)C1)C2,,ClCCl,,,,test
US20150225404A1,CI.c1ccc(COc2cc(-c3cncc(OC4CNC4)c3)c3c(n2)CCCC3)nc1>>CN1CC(Oc2cncc(-c3cc(OCc4ccccn4)nc4c3CCCC4)c2)C1,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060293310A1,CNC(=O)CO.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CNC(=O)COC(=O)Oc1ccc([N+](=O)[O-])cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040067999A1,CCN(CC)CC.Cc1cc2c(c(C)c1N)c1ccccc1n2C(C)C.O=C(Cl)Oc1ccccc1>>CCCC(C)C.Cc1cc2c(c(C)c1NC(=O)Oc1ccccc1)c1ccccc1n2C(C)C,,C1CCOC1,,,,test
US06353008B1,CC(C)(C)OC(=O)N1CCC(=O)C1.CCCC[SnH](CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)C1(O)CCN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US04871872,CC(N)(Cc1ccccc1)c1ccccc1.O=C(O)C(O)(C(=O)c1ccccc1)C(O)(C(=O)O)C(=O)c1ccccc1>>CC(N)(Cc1ccccc1)c1ccccc1.O=C(O)C(O)(C(=O)c1ccccc1)C(O)(C(=O)O)C(=O)c1ccccc1,,CCO,,O,,test
US20120122843A1,CC#N.Cc1cc(Cl)nc(Cl)c1CBr.Cc1csc(C(O)CN)n1>>Cc1csc(C(O)CNCc2c(C)cc(Cl)nc2Cl)n1.N,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US06740662B1,CCn1c(=O)c(CCCO)c(-c2cccc(Cl)c2)c2ccc(C)nc21.CS(=O)(=O)Cl>>CCn1c(=O)c(CCCOS(C)(=O)=O)c(-c2cccc(Cl)c2)c2ccc(C)nc21,,CCN(CC)CC,,C1CCOC1,,test
US05646173,CC(O)CN.COc1cc2c(cc1OC)C(=O)C(CC=O)C2>>COc1cc2c(cc1OC)-c1c(ccn1CC(C)O)C2,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US06114369,CN(CCCN(C)c1nc2ccccc2[nH]1)C(=O)OC(C)(C)C.Fc1ccc(CCl)cc1>>CN(CCCN(C)c1nc2ccccc2n1Cc1ccc(F)cc1)C(=O)OC(C)(C)C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100048881A1,COCCOC(=O)N=NC(=O)OCCOC.C[C@H](O)c1ccccc1.ClCCl.O=C(O)c1ccc([N+](=O)[O-])cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>C[C@@H](OC(=O)c1ccc([N+](=O)[O-])cc1)c1ccccc1.C[C@H](O)c1ccccc1,,ClCCl,O,,,test
US20050153942A1,Cn1cnc2c(F)c(Nc3ccc(Br)cc3F)c(C(=O)NN)nc21.N#CBr>>Cn1cnc2c(F)c(Nc3ccc(Br)cc3F)c(-c3nnc(N)o3)nc21,,C1COCCO1,O,O=C([O-])O.[Na+],,test
US20090275609A1,CC(C)(C)OC(=O)N1CCC(NC(=O)c2nc3ccc(O)cc3s2)CC1.OC1CCN(c2ccc(C(F)(F)F)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(NC(=O)c2nc3ccc(OC4CCN(c5ccc(C(F)(F)F)cc5)CC4)cc3s2)CC1,,Cc1ccccc1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100317651A1,CN(c1cnc(C=O)c(Cl)n1)C1CCC1.OCCNCc1ccccc1>>CN(c1cnc(CN(CCO)Cc2ccccc2)c(Cl)n1)C1CCC1,,CC#N,CC(=O)O,O=C([O-])O.[Na+],,test
US20150045213A1,ON=C1CCC1c1ccc(Cl)cc1>>NC1CCC1c1ccc(Cl)cc1,,CO,,[BH4-].[Na+],,test
US20050054658A1,N[C@H]1CC[C@H](O)C1.O=C1CCC(=O)N1C(=O)OCc1ccccc1>>O=C(N[C@H]1CC[C@H](O)C1)OCc1ccccc1,,CC#N,,,,test
US20100317651A1,CC(C)Sc1cnc2c(n1)OCCN(Cc1ccccc1)C2.CC(Cl)OC(=O)Cl>>CC(C)Sc1cnc2c(n1)OCCNC2.Cl,,Cc1ccccc1,,,,test
US04705786,C1CCNCC1.CC(=O)Cc1nc(CCl)no1>>CC(=O)Cc1nc(CN2CCCCC2)no1,,C1CCOC1,,CCN(CC)CC,,test
US06174901B1,Cc1cccc(C2(O)CNC(=O)C=C2c2ccncc2)c1>>Cc1cccc(-c2c[nH]c(=O)cc2-c2ccncc2)c1,,ClC(Cl)Cl,,O=S(=O)(O)O,,test
US20100087418A1,CC(C)(C)OC(=O)N1CCOc2c(cccc2C2CC2)C1.Cl>>Cl.c1cc2c(c(C3CC3)c1)OCCNC2,,CCOC(C)=O,,,,test
US20110092505A1,CC(C)(C)N.COC(=O)c1cc(Cl)nc(Cl)c1>>CC(C)(C)NC(=O)c1cc(Cl)nc(Cl)c1,,Cc1ccccc1,,C[Al](C)C,,test
US05276150,CC(=O)Cc1ccccn1.O=Cc1cccc([N+](=O)[O-])c1>>C=CC(=O)Cc1cnccc1-c1cccc([N+](=O)[O-])c1,,c1ccccc1,,C1CC[NH2+]CC1.CC(=O)[O-],,test
US20120225858A1,C[C@@](N)(c1ccccc1F)[C@H]1COC[C@H]1OC=O>>C[C@@](N)(c1ccccc1F)[C@H]1COC[C@H]1O,,ClCCl,,O=C([O-])O.[Na+],,test
US20120202871A1,BrCC1CO1.CCCCC/C=C\C/C=C\CCCCCCCCO>>CCCCC/C=C\C/C=C\CCCCCCCCOCC(O)CBr,,ClCCl,,CCOCC,FB(F)F,test
US20110152273A1,Cc1cccc(Nc2nc(N[C@@H]3CCCC[C@@H]3NC(=O)OC(C)(C)C)c(Cl)c3c2C(=O)NC3)c1.O=C(O)C(F)(F)F>>Cc1cccc(Nc2nc(N[C@@H]3CCCC[C@@H]3N)c(Cl)c3c2C(=O)NC3)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20030207400A1,COC(=O)c1cc([N+](=O)[O-])c[nH]1.ClCCl>>COC(=O)c1cc(N)cn1C.Cl,[Pd],CCOC(C)=O,,CO,,test
US20160083367A1,C[C@H](N)c1cc2cc(Cl)ccc2[nH]c1=O.Fc1cc(Br)ccn1>>C[C@H](Nc1cc(Br)ccn1)c1cc2cc(Cl)ccc2[nH]c1=O,,CCOC(C)=O,CS(C)=O,Cl,O=C([O-])[O-].[K+].[K+],test
US20150148313A1,CN(Cc1cc([N+](=O)[O-])ccc1SC1CC1)C(=O)OC(C)(C)C>>CN(Cc1cc(N)ccc1SC1CC1)C(=O)OC(C)(C)C,[Zn],CCO,,[Cl-].[NH4+],,test
US05266701,CCC1CO1.N#CNc1ccccc1>>CCC1CN(c2ccccc2)C(=N)O1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05334598,CCOC(=O)C(Oc1c(Cl)cc(CBr)cc1Cl)c1ccc2c(c1)OCO2.CCc1nc2nc(C)cc(C)c2[nH]1>>CCc1nc2c(C)cc(C)nc2n1Cc1cc(Cl)c(OC(C(=O)O)c2ccc3c(c2)OCO3)c(Cl)c1,,CN(C)C=O,,[H-].[Na+],,test
US04766133,CCCS.Cl.O=S(Cc1ccccn1)c1nc2ccccc2[nH]1>>CCCSSCc1cccc[n+]1-c1nc2ccccc2[nH]1.[Cl-],,C1CCOC1,,,,test
US20050054696A1,NNC(=O)c1cc2cc(Cl)ccc2[nH]1.O=C(O)CCNc1ccccc1>>O=C(CCNc1ccccc1)NNC(=O)c1cc2cc(Cl)ccc2[nH]1,,CN(C)C=O,O,ClCCCl,On1nnc2ccccc21,test
US04430339,C=C(CCCC1CCCCCCC1)C(=O)OCC.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)C1(CCCC2CCCCCCC2)CO1,,ClCCl,,,,test
US20050250836A1,Cn1c(CO)c(Cl)c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O.OCCO>>Cn1c(COCCO)c(Cl)c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O,O=S(=O)(O)O,,,O,,test
US20120016119A1,CN(C)C(=O)c1ccc(Nc2ncnc3c2c(F)cn3C2CCN(C(=O)OC(C)(C)C)CC2)c(F)c1.CS(=O)(=O)c1ccc(O)c(F)c1>>CC(C)(C)OC(=O)N1CCC(n2cc(F)c3c(Oc4ccc(S(C)(=O)=O)cc4F)ncnc32)CC1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120165324A1,CN.O=C(CCl)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1>>CNCC(=O)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1,,O,,C1CCOC1,,test
US20120046273A1,CC(C)(C)OC(=O)N1CCCC(C(N)=S)C1.COC(C)(OC)N(C)C>>CC(=NC(=S)C1CCCN(C(=O)OC(C)(C)C)C1)N(C)C,,ClCCl,,,,test
US20060270725A1,Nc1nnc(S)n1-c1ccc(C2CC2)c2ccccc12.O=C(CCl)Nc1ccc(C(=O)O)cc1Cl>>Nc1nnc(SCC(=O)Nc2ccc(C(=O)O)cc2Cl)n1-c1ccc(C2CC2)c2ccccc12,,CN(C)C=O,,O,,test
US20150166564A1,N[C@@H]1CN(C(CF)CF)C[C@H]1c1ccccc1.O=C(Nc1c2c(nn1-c1ccccc1)CCC2)Oc1ccccc1>>O=C(Nc1c2c(nn1-c1ccccc1)CCC2)N[C@@H]1CN(C(CF)CF)C[C@H]1c1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20130338133A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.FC(F)(F)CCNc1cc(Br)nn2ccnc12>>CC(C)(C)OC(=O)N(CCC(F)(F)F)c1cc(Br)nn2ccnc12,CN(C)c1ccncc1,C1CCOC1,,CCOC(C)=O,,test
US20120214762A1,C#Cc1ccc2c(C(=O)N(C)C)nn(-c3ccnc(N)n3)c2c1.CC(=O)c1nccn1COCC[Si](C)(C)C>>Cc1nn(-c2ccnc(N)n2)c2cc(C#CC(C)(O)c3nccn3COCC[Si](C)(C)C)ccc12,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20060052374A1,CC1CN(c2ncccc2C#N)CC(C)O1>>CC1CN(c2ncccc2CN)CC(C)O1,[Ni],,,,,test
US20120001161A1,CC(C)(C)c1cc2ccc3cccc4ccc(c1)c2c34.O=C1CCC(=O)N1Br>>CC(C)(C)c1cc2ccc3ccc(Br)c4ccc(c1)c2c34,,C1CCOC1,,,,test
US20130296281A1,N#Cc1cc(Oc2ccc(-n3cc(C(=O)C(N)=O)c4ccccc43)cc2)ccc1C(F)(F)F>>N#Cc1cc(Oc2ccc(-n3cc(C(O)C(N)=O)c4ccccc43)cc2)ccc1C(F)(F)F,,C1CCOC1,CCO,[BH4-].[Na+],,test
US20090270374A1,COc1cnc2ccc(=O)n(CCN3CC[C@@H](CNC(=O)OCc4ccccc4)C3)c2c1>>COc1cnc2ccc(=O)n(CCN3CC[C@@H](CN)C3)c2c1,[Pd],CO,,,,test
US04918091,[N-]=[N+]=NCCOc1ccc(CC2SC(=O)NC2=O)cc1>>NCCOc1ccc(CC2SC(=O)NC2=O)cc1,[Pd],CO,,,,test
US20050014749A1,CC(C)(C)OC(=O)N[C@@H]1CCc2cc(Br)ccc2C1.ClCCl.O=C(O)C(F)(F)F>>C=Cc1ccc2c(c1)CC[C@@H](NC(=O)OC(C)(C)C)C2,,ClCCl,,,,test
US20060074111A1,CCOC(=O)COc1ccc(CNCCOC)cc1C.CS(=O)(=O)c1nccc(-c2ccc(C(F)(F)F)cc2)n1>>CCOC(=O)COc1ccc(CN(CCOC)c2nccc(-c3ccc(C(F)(F)F)cc3)n2)cc1C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070244087A1,CC(C)(C)OC(=O)NC1CSCCN(Cc2ccc3ccccc3c2)C1=O.Cl>>Cl.NC1CSCCN(Cc2ccc3ccccc3c2)C1=O,,C1COCCO1,,,,test
US20060293343A1,CCOC(=O)Cc1ccc(N)cc1.CCc1c(C)nc(-c2ccc(Br)s2)nc1Cl>>CCOC(=O)Cc1ccc(Nc2nc(-c3ccc(Br)s3)nc(C)c2CC)cc1,,CCO,,Cl,,test
US20020160986A1,CCCN(CCC)C1(c2ccc(C#C[Si](C)(C)C)cc2)CC1>>C#Cc1ccc(C2(N(CCC)CCC)CC2)cc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20150133495A1,O/N=C/c1ccccc1Cl.O=C1CCC(=O)N1Cl>>O/N=C(\Cl)c1ccccc1Cl,,CN(C)C=O,,O,,test
US20070099990A1,CCCN.Cc1c(C)c2c(c(C)c1NC(=O)OCC(Cl)(Cl)Cl)C(c1ccc(C(C)C)cc1)CO2>>CCCNC(=O)Nc1c(C)c(C)c2c(c1C)C(c1ccc(C(C)C)cc1)CO2,,CCCCCC,CCOC(C)=O,,,test
US20110190255A1,O/N=C/c1ccccc1.O=C1CCC(=O)N1Cl>>O/N=C(\Cl)c1ccccc1,,CN(C)C=O,O,,,test
US20140296246A1,O=C1CCC(=O)N1Br.c1c(C2CC2)noc1C1CC1>>Brc1c(C2CC2)noc1C1CC1,,ClCCl,,,,test
US04656182,CN[C@@H]1CCCC[C@H]1N1CCCC1.O=C(O)Cc1c[nH]c2ccccc12.O=S(Cl)Cl>>CN(C(=O)Cc1c[nH]c2ccccc12)[C@@H]1CCCC[C@H]1N1CCCC1.Cl,,ClCCl,,CCOCC,,test
US20040242608A1,C[C@@H](N)CO.Cc1ccc(C(=O)O)cc1-n1c(C)nc(OCc2ccc(F)cc2F)c(Br)c1=O>>Cc1ccc(C(=O)N[C@H](C)CO)cc1-n1c(C)nc(OCc2ccc(F)cc2F)c(Br)c1=O,,CC(=O)N(C)C,ClCCl,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20150376130A1,CCOC(=O)c1ccc(C(F)(F)F)nc1NC(C)C>>CC(C)Nc1nc(C(F)(F)F)ccc1C(=O)O,,C1CCOC1,,[Na+].[OH-],,test
US05716964,CC(C)(C)C(=O)Nc1cccc(CBr)n1.O=S(=O)(O)O>>Nc1cccc(CO)n1,,O=S(=O)(O)O,,O=C([O-])[O-].[K+].[K+],,test
US20130136794A1,C=CC=O.NCc1ccco1.S=C=S>>OC1CCSC(=S)N1Cc1ccco1,,O,,CCN(CC)CC,,test
US20070129379A1,CC(Cl)C#N.SCCCCl>>CC(C#N)SCCCCl,,CC#N,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20120149711A1,C[C@H]1CC[C@@H](CNc2ncc(F)cc2F)N(C(=O)OC(C)(C)C)C1>>C[C@H]1CC[C@@H](CNc2ncc(F)cc2F)NC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090192144A1,COc1ccc(C(C)(N)CO)cc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COc1ccc(C(C)(N)CS)cc1,,Cc1ccccc1,,,,test
US20080234268A1,Nc1ccc(Br)c(F)c1.OB(O)c1cccc2cnccc12>>Nc1ccc(-c2cccc3cnccc23)c(F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US04035495,CCOC(=O)C(C)=O.Oc1ccccc1-n1cccc1>>CCOC(=O)C1(C)Oc2ccccc2-n2cccc21,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20150225405A1,CC1(C)OB(c2ccnn2C2CCCCO2)OC1(C)C.[N-]=[N+]=Nc1cc(Cl)ccc1Br>>[N-]=[N+]=Nc1cc(Cl)ccc1-c1ccnn1C1CCCCO1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US06358985B1,O=S(Cl)Cl.OCc1ccccc1-c1cccc(OCc2ccccc2)c1>>ClCc1ccccc1-c1cccc(OCc2ccccc2)c1,,ClCCl,,,,test
US20100197683A1,CCCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(=O)N(C)OC)CC2)c2ccnn12.C[Mg]Br>>CCCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(C)O)CC2)c2ccnn12,,C1CCOC1,,CCOC(C)=O,[Cl-].[NH4+],test
US05270322,CCCc1nc2c(C)cccn2c1C(=O)OCC>>CCCc1nc2c(C)cccn2c1C(=O)O,,CCO,,[Na+].[OH-],,test
US20090239845A1,CC(C)N.Cc1cc(C(=O)O)nn1Cc1cc(Cl)ccc1OCc1ccccc1>>Cc1cc(C(=O)NC(C)C)nn1Cc1cc(Cl)ccc1OCc1ccccc1,,CCOCC,ClCCl,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20130023526A1,CCOC(=O)CBr.Oc1ccc(Cl)nn1>>CCOC(=O)Cn1nc(Cl)ccc1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040092533A1,CCCC[Sn](CCCC)(CCCC)c1nccs1.CC[Si](CC)(CC)OC(C)(C)c1ccn2c(-c3ccnc(Cl)n3)cnc2n1>>CC[Si](CC)(CC)OC(C)(C)c1ccn2c(-c3ccnc(-c4nccs4)n3)cnc2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,N#N,,test
US05981737,C1COCCO1.O=C([O-])c1ccccc1C(=O)O.[K+].[O-][Cl+3]([O-])([O-])O>>C1COCCO1.O=C([O-])c1ccccc1C(=O)O.[K+].[O-][Cl+3]([O-])([O-])O,,CC(=O)O,,,,test
US20040110767A1,COC(=O)CCc1ccc(N(Cc2cccc(O)c2)S(=O)(=O)c2c(C)cc(C)cc2C)cc1>>Cc1cc(C)c(S(=O)(=O)N(Cc2cccc(O)c2)c2ccc(CCC(=O)O)cc2)c(C)c1,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20100160319A1,C1CN[C@H](CN2CCCC2)C1.O=C(Cl)C(=O)Cl.O=C(O)c1ccc(NS(=O)(=O)Cc2ccccc2)cc1>>Cl.O=C(c1ccc(NS(=O)(=O)Cc2ccccc2)cc1)N1CCC[C@H]1CN1CCCC1,CN(C)C=O,ClCCl,,CN1CCOCC1,,test
US20080221185A1,CCOC(=O)CN1C(=O)C(c2ccc(C)cc2)=NC12CCCCC2>>Cc1ccc(C2=NC3(CCCCC3)N(CC(=O)O)C2=O)cc1,,CO,,O,[Na+].[OH-],test
US20100317528A1,CS(=O)(=O)Cl.Cc1c(Cl)cccc1Cl>>Cc1c(Cl)ccc(S(C)(=O)=O)c1Cl,,CCCCCC,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US04263207,N#Cc1ccc2c(c1)Sc1ccccc1NC2=O.O=CO>>O=Cc1ccc2c(c1)Sc1ccccc1NC2=O,[Ni],,,,,test
US06025372,CC(C)(C)OC(=O)NCc1ccnc(CN)c1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)NCc1ccnc(CNC(=O)OCc2ccccc2)c1,CN(C)c1ccncc1,ClCCl,,CN1CCOCC1,,test
US20110046169A1,CC(C)(C)OC(=O)Nc1ccc(Oc2ccc3nc(N)sc3n2)c(F)c1.O=C(Cl)C1CC1>>CC(C)(C)OC(=O)Nc1ccc(Oc2ccc3nc(NC(=O)C4CC4)sc3n2)c(F)c1,,CC(=O)N(C)C,,CCN(CC)CC,O,test
US20100105667A1,C=O.CCNCC.O=[N+]([O-])c1ncc[nH]1>>CCN(CC)Cc1c[nH]c([N+](=O)[O-])n1,,CCO,,,,test
US20130178459A1,CC[C@@H](NC(=O)OC(C)(C)C)c1ccc(-c2c(OC)ccc3[nH]c(=O)c4sccc4c23)cc1.O=C1CCC(=O)N1Cl>>CC[C@@H](NC(=O)OC(C)(C)C)c1ccc(-c2c(OC)cc(Cl)c3[nH]c(=O)c4sccc4c23)cc1,,CN(C)C=O,,,,test
US20060154877A1,C=C(CO)C(CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)OC(=O)/C=C/c1ccc(O)c(O)c1>>O=C(O)/C=C/c1ccc(O)c(O)c1.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO,,O,,,,test
US20140018325A1,CCOC(=O)[C@H](CC(F)CCNC(=O)[C@@H](NC(=O)OC)C(c1ccccc1)c1ccccc1)N(C(C)C)S(=O)(=O)c1ccc([N+](=O)[O-])cc1>>CCOC(=O)[C@H](CC(F)CCNC(=O)[C@@H](NC(=O)OC)C(c1ccccc1)c1ccccc1)N(C(C)C)S(=O)(=O)c1ccc(N)cc1,[Pd],CCOC(C)=O,,,,test
US20070281952A1,CC(=O)c1ccc(F)cc1.Nc1ncc(Br)cc1C=O>>Fc1ccc(-c2ccc3cc(Br)cnc3n2)cc1,,CCO,,[K+].[OH-],,test
US20100113608A1,Nc1ccc(S)cc1.O=[N+]([O-])c1ccc(Cl)cc1>>O=[N+]([O-])c1ccc(Nc2ccc(S)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05998433,CN(C)Cc1cc2c(o1)CN(C(=O)c1ccccc1C(=O)c1ccccc1)CC2.Cl>>CN(C)Cc1cc2c(o1)CN(C(=O)c1ccccc1C(=O)c1ccccc1)CC2.Cl,,CCOC(C)=O,CO,,,test
US20040152699A1,O=C(O)Cn1c(-c2cccs2)n[nH]c1=S>>OCCn1c(-c2cccs2)n[nH]c1=S,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05104888,CC(=O)Oc1cc2c(cc1C(C)(C)CC(C)(C)C)OC(C)(COc1ccc([N+](=O)[O-])cc1)CC2=O>>CC(=O)Oc1cc2c(cc1C(C)(C)CC(C)(C)C)OC(C)(COc1ccc(N)cc1)CC2=O,[Pd],CO,c1ccccc1,[H][H],,test
US20100069394A1,CC(C)(C)OC(=O)N1CCN(c2cc(-c3ccc(F)cc3)c(C(F)(F)F)nn2)CC1>>Fc1ccc(-c2cc(N3CCNCC3)nnc2C(F)(F)F)cc1,,CO,,,,test
US05015661,Brc1csc2ccccc12.C#CC1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1>>CC(=O)Oc1c(C)c(C)c2c(c1C)CCC(C)(C#Cc1csc3ccccc13)O2,,CN(C)C=O,,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060270656A1,CCOC(=O)c1csc(CC)n1.ClC(Cl)(Cl)C(Cl)(Br)Br>>CCOC(=O)c1nc(CC)sc1Br,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20150111885A1,COc1cc(F)c(CSC)cc1Br.O=S([O-])OO>>COc1cc(F)c(CS(C)(=O)=O)cc1Br,,CO,,O,,test
US04016174,CCN(CC)c1ccc(C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2C(=O)O)cc1.CCn1c(C)cc2ccc3ccccc3c21>>CCN(CC)c1ccc(C2(c3c(C)n(CC)c4c3ccc3ccccc34)OC(=O)c3c(Cl)c(Cl)c(Cl)c(Cl)c32)cc1,,CC(=O)OC(C)=O,,N,,test
US20090156612A1,NC1CCCCC1.[C-]#[N+]C(C(=O)OC)=C(Br)c1ccccc1>>COC(=O)c1ncn(C2CCCCC2)c1-c1ccccc1,,CN(C)C=O,,CCN(CC)CC,,test
US08916702B2,CCOC(=O)C(=O)NC1CCCC1CNC(=O)c1ccc(Nc2nc(NC3(c4ccc(Cl)cc4)CC3)nc(OCC(F)(F)F)n2)cc1.Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)C(=O)NC1CCCC1CNC(=O)c1ccc(Nc2nc(NC3(c4ccc(Cl)cc4)CC3)nc(OCC(F)(F)F)n2)cc1,,CCO,,CCN(C(C)C)C(C)C,,test
US04739106,CCOC(=O)/C=C(\N)COC(N)=O.CCOC(=O)C(=Cc1ccccc1[N+](=O)[O-])C(C)=O>>CCOC(=O)C1=C(C)NC(COC(N)=O)=C(C(=O)OCC)C1c1ccccc1[N+](=O)[O-],,CCO,,CCCCCC,CCOC(C)=O,test
US05866724,C=O.CC(=O)O.Cc1ccc(O)c(Cc2c(C)c(Cc3cc(C)c(O)c(Cc4cc(C)ccc4O)c3C)cc(C)c2O)c1>>Cc1cc(CO)c(O)c(Cc2c(C)c(Cc3cc(C)c(O)c(Cc4cc(C)cc(CO)c4O)c3C)cc(C)c2O)c1,,C1CCOC1,,O,[Na+].[OH-],test
US05116869,CCCCCC(C=CC1C=CC(=O)C1C(O)CCCCCC(=O)OC)O[Si](C)(C)C(C)(C)C.OO>>CCCCCC(C=CC1C2OC2C(=O)C1C(O)CCCCCC(=O)OC)O[Si](C)(C)C(C)(C)C,,CO,,[Na+].[OH-],,test
US20160244437A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2cccc(-c3ccc(C(=O)NCCN4CCCCC4)cc3)c2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)CC1.Cl>>Cl.NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2cccc(-c3ccc(C(=O)NCCN4CCCCC4)cc3)c2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)CC1,,C1COCCO1,,CC#N,,test
US20100331298A1,Cc1ccc2ccc(=O)n(C)c2c1.NC(=O)CCC(=O)NBr>>Cn1c(=O)ccc2ccc(CBr)cc21,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20090156600A1,COC(=O)CBr.Cc1nc2c(Cl)ccc(O)c2c(C)c1Oc1ccc(Cl)cc1>>COC(=O)COc1ccc(Cl)c2nc(C)c(Oc3ccc(Cl)cc3)c(C)c12,,ClCCl,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20030232848A1,CC(C)c1ccc(S(=O)(=O)Cl)cc1.COc1nn(C)c(N)c1-c1ccc2c(c1)OCO2>>COc1nn(C)c(NS(=O)(=O)c2ccc(C(C)C)cc2)c1-c1ccc2c(c1)OCO2,,c1ccncc1,,CN(C)c1ccccn1,,test
US20010049371A1,CCOc1cc(C(CC(=O)O)N2C(=O)c3ccc([N+](=O)[O-])cc3C2=O)ccc1OC.NOCc1ccccc1>>CCOc1cc(C(CC(=O)NOCc2ccccc2)N2C(=O)c3ccc([N+](=O)[O-])cc3C2=O)ccc1OC,,C1CCOC1,,Cl,O=C(n1ccnc1)n1ccnc1,test
US20020037889A1,BrCCBr.CCOC(=O)Cc1cccnc1>>COC(=O)C1(c2cccnc2)CC1,,C1CCOC1,CN(C)P(=O)(N(C)C)N(C)C,CC(C)[N-]C(C)C.[Li+],,test
US20080318924A1,C1CCOC1.CCN(CC)CC.Nc1cc(Oc2cc(F)c(NC(=O)CC3(CC(=O)Nc4ccc(F)cc4)CC3)cc2F)ccn1.O=C(Cl)Oc1ccccc1>>O=C(CC1(CC(=O)Nc2cc(F)c(Oc3ccnc(NC(=O)N4CC(O)C4)c3)cc2F)CC1)Nc1ccc(F)cc1,,C1CCOC1,CCOC(C)=O,O=C([O-])O.[Na+],,test
USRE030538,CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC4OCCO[C@@]45CCCC[C@]5(C)[C@H]3CC[C@]12C.CCOC(C)=O>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC4(OCCO4)[C@H]4CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C,,c1ccncc1,,,,test
US04167508,O=C(O)CCc1ccc(O)cc1.O=[N+]([O-])c1ccc(CBr)cc1>>O=C(CCc1ccc(O)cc1)OCc1ccc([N+](=O)[O-])cc1,,CN(C)C=O,,CCN(CC)CC,,test
US20080269196A1,C1CCNCC1.N#Cc1ccc(C=O)cc1>>N#Cc1ccc(CN2CCCCC2)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20150239921A1,CCOP(=O)(OCC)c1ccc2c(C(=O)O)nn(CC(=O)N3C[C@H](F)C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c1.[NH4+]>>CCOP(=O)(OCC)c1ccc2c(C(N)=O)nn(CC(=O)N3C[C@H](F)C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120196845A1,COCCN(CCOC)S(F)(F)F.O=c1c2cn(Cc3ccc(-n4cccn4)cc3)c3ccccc3c-2nn1[C@@H]1CCCC[C@H]1O>>O=c1c2cn(Cc3ccc(-n4cccn4)cc3)c3ccccc3c-2nn1[C@@H]1CCCC[C@@H]1F,,ClCCl,,O=C([O-])O.[Na+],,test
US20040072818A1,CC1CCCC(N)C1C.Clc1ccc2c(N3CCNCC3)ccnc2c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC1CCCC(NC(=O)N2CCN(c3ccnc4cc(Cl)ccc34)CC2)C1C,,CO,ClCCl,CCN(C(C)C)C(C)C,,test
US04361511,CC1N=C(c2ccccc2Cl)c2cc([N+](=O)[O-])ccc2NC1=O.CI>>CC1N=C(c2ccccc2Cl)c2cc([N+](=O)[O-])ccc2N(C)C1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100160303A1,NC(=O)c1ccc(Br)c2c1[nH]c1cc(CO)ccc12>>NC(=O)c1ccc(Br)c2c1[nH]c1cc(C=O)ccc12,,C1CCOC1,CCOC(C)=O,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20150011548A1,CC(=O)Nc1cc(-c2ccc(F)cc2F)cc([N+](=O)[O-])c1>>CC(=O)Nc1cc(N)cc(-c2ccc(F)cc2F)c1,[Pd],CCOC(C)=O,CO,,,test
US05523476,COC(=O)c1cc(F)c(F)c(F)c1F>>O=C(O)c1cc(F)c(F)c(F)c1F,,O,,O=S(=O)(O)O,,test
US20080255124A1,CC(=O)Nc1ccc(OCc2ccccc2)nc1>>CC(=O)Nc1ccc(O)nc1,[Pd],CCO,,,,test
US20080132486A1,C=O.COc1cc(C)ccn1>>COc1cc(CCO)ccn1,,C1CCOC1,,[Li]CCCC,,test
US20090088425A1,COC(=O)Cn1ccc(C(O)(C(C)c2ccc(Cl)cc2Cl)C(F)(F)F)cc1=O>>CC(c1ccc(Cl)cc1Cl)C(O)(c1ccn(CC(=O)O)c(=O)c1)C(F)(F)F,,CO,,Cl,[Na+].[OH-],test
US20130064770A1,O=C1c2ccccc2C(=O)N1CCCCN1CCN(Cc2ccccc2)CC1>>NCCCCN1CCN(Cc2ccccc2)CC1,,CCO,,NN,O,test
US20150361101A1,CCN(CC)S(F)(F)F.CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3C(CO)C4)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3C(CF)C4)cc12,,CCOC(C)=O,ClCCl,,,test
US20100081643A1,COC(=O)c1cc(N)c(C)cc1C.O=N[O-]>>COC(=O)c1cc(O)c(C)cc1C,,O,,O=S(=O)(O)O,,test
US06323011B1,COc1cc(/C=C/C(=O)O)ccc1O>>COc1cc(C=O)ccc1O,,CO,,CC(=O)[O-].[Na+],,test
US20090163503A1,CCOC(=O)n1nc2c(c1NC(=O)c1ccccc1CN1C(=O)c3ccccc3C1=O)CNC2(C)C.O=S(=O)(Cl)c1cc(F)cc(F)c1>>CCOC(=O)n1nc2c(c1NC(=O)c1ccccc1CN1C(=O)c3ccccc3C1=O)CN(S(=O)(=O)c1cc(F)cc(F)c1)C2(C)C,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20120258952A1,CI.Cc1ccc[nH]c1=O>>Cc1cccn(C)c1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04943585,Cc1ccc(S(=O)(=O)[O-])cc1CCOc1ccc(Oc2ccccc2)cc1.Clc1nc[nH]c1Cl>>Clc1ncn(CCOc2ccc(Oc3ccccc3)cc2)c1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20090005356A1,Clc1c(Br)cnc2[nH]ccc12.[N-]=[N+]=[N-]>>[N-]=[N+]=Nc1c(Br)cnc2[nH]ccc12,,CN(C)C=O,O,[Cl-].[NH4+],,test
US20130178597A1,O=C(O)c1cccc(-c2cccc(C(=O)O)c2C(=O)O)c1C(=O)O>>O=C1OC(=O)c2cc(-c3cccc4c3C(=O)OC4=O)ccc21,,CN1CCCC1=O,,,,test
US06432976B1,CCOC(=O)N1C2CCC1CC(Cc1ccc(Cl)cc1)C2>>Clc1ccc(CC2CC3CCC(C2)N3)cc1,,CC(=O)O,,Br,[Na+].[OH-],test
US20090054463A1,COC(=O)C1CCC(N(CCC(c2ccccc2)c2ccccc2)C(=O)Nc2nc3ccccc3s2)C1>>O=C(O)C1CCC(N(CCC(c2ccccc2)c2ccccc2)C(=O)Nc2nc3ccccc3s2)C1,,CO,O,[Li+].[OH-],,test
US05972976,COc1ccc(S(=O)(=O)Nc2ccccc2/C=C/c2ccncc2)cc1.Cl>>COc1ccc(S(=O)(=O)Nc2ccccc2/C=C/c2ccncc2)cc1.Cl,,CO,,,,test
US20140336192A1,BrCc1ccccc1.O=C1NC(c2ccc(Br)cc2)=COc2ccc(F)cc21>>Fc1ccc2c(c1)C(OCc1ccccc1)=NC(c1ccc(Br)cc1)=CO2,,Cc1ccccc1,,,,test
US04576933,CCCCCCCCCCCCCCCCCCNC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OCc1ccccc1>>CCCCCCCCCCCCCCCCCCNC(=O)OCC(O)COP(=O)([O-])OCC[N+](C)(C)C,[Pd],CC(=O)O,,,,test
US20050014210A1,CCOC(=O)C1Oc2ccc(CC(C)N(CC)C(=O)OC(C)(C)C)cc2O1>>CCN(C(=O)OC(C)(C)C)C(C)Cc1ccc2c(c1)OC(C(=O)O)O2,,CO,O,[Li+].[OH-],,test
US20100197678A1,CC1(C)OCC(Cn2cc(C(=O)C(F)(F)F)c3ccccc32)O1.Fc1ccc(-c2ncc3cc(Br)ccn23)cc1>>CC1(C)OCC(Cn2cc(C(O)(c3ccn4c(-c5ccc(F)cc5)ncc4c3)C(F)(F)F)c3ccccc32)O1,,C1CCOC1,,[Li]CCCC,,test
US20050267170A1,COC(=O)c1cc(Cl)ccc1COc1ccccc1Cl>>O=C(O)c1cc(Cl)ccc1COc1ccccc1Cl,,C1CCOC1,CO,[Na+].[OH-],,test
US20020147188A1,C=CCC(C)(C)C=O.C=CCN>>C=CCN=CC(C)(C)CC=C,,c1ccccc1,,,,test
US20090176847A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCC1(O)CC2CC(NCC(=O)N3CCCC3C#N)CC2C1>>CCC1(O)CC2CC(N(CC(=O)N3CCCC3C#N)C(=O)OC(C)(C)C)CC2C1,,ClCCl,,O,O=C([O-])[O-].[K+].[K+],test
US04847256,CN(C)C=CC(=O)c1cc(Cl)ccc1Cl.Cc1[nH]nc(N)c1C#N>>Cc1nn2c(-c3cc(Cl)ccc3Cl)ccnc2c1C#N,,CC(=O)O,,,,test
US04831029,CN(C)c1n[nH]c(N)n1.COC(=O)C1CN(Cc2ccccc2)CCC1=O>>CN(C)C1=NC2=NC3=C(CN(Cc4ccccc4)CC3=O)CN2N1,,CC(=O)O,,Cl,[NH4+].[OH-],test
US20110251247A1,CC(=O)Cl.NCc1cc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)ccc1Br>>CC(=O)NCc1cc(C2=NOC(c3cc(Cl)c(Cl)c(Cl)c3)(C(F)(F)F)C2)ccc1Br,,CN(C)C=O,,O,c1ccncc1,test
US20030055265A1,COC(Cl)Cl.c1ccc(COc2cccc3ccsc23)cc1>>O=Cc1ccc(OCc2ccccc2)c2sccc12,,ClCCl,,,,test
US20080269268A1,Cc1c[nH]c2nccc(Nc3ccc([N+](=O)[O-])cc3F)c12>>Cc1c[nH]c2nccc(Nc3ccc(N)cc3F)c12,[Pd],CCO,,[H][H],,test
US05658901,[N-]=[N+]=NC1N=C(c2ccccc2)c2ccccc2N(CC(F)(F)F)C1=O>>NC1=CN(CC(F)(F)F)c2ccccc2C(c2ccccc2)=N1,[Pd],C1CCOC1,CCO,,,test
US06194450B1,Br.COC(=O)c1ccc(CO)c(O)c1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>COC(=O)c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c(O)c1.[Br-],,CC#N,,,,test
US20110237573A1,Cc1cc(CC(=O)O)cnc1-c1cc[n+]([O-])c(C)c1.Nc1ccc(-c2cnccn2)cn1>>Cc1cc(CC(=O)Nc2ccc(-c3cnccn3)cn2)cnc1-c1cc[n+]([O-])c(C)c1,CN(C)c1ccncc1,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20090023789A1,CCCCc1cn(C(C)(C)C)s/c1=N\C(=O)c1cc(C#C[Si](C)(C)C)ccc1OC>>C#Cc1ccc(OC)c(C(=O)/N=c2\sn(C(C)(C)C)cc2CCCC)c1,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100010038A1,CC(=O)Nc1ccc(Br)c(C(=O)O)c1.O=[N+]([O-])O>>CC(=O)Nc1ccc(Br)c(C(=O)O)c1[N+](=O)[O-],,O,,,,test
US20160137584A1,CCOC(=O)C(C)(C)CCCCOCc1ccccc1>>CCOC(=O)C(C)(C)CCCCO,[Pd],CCOC(C)=O,,[H][H],,test
US20060111375A1,COc1cc2c(Oc3cc4ccccc4nc3C)ccnc2cc1OCCN1C(=O)c2ccccc2C1=O>>COc1cc2c(Oc3cc4ccccc4nc3C)ccnc2cc1OCCN,,CN(C)C=O,,NN,,test
US20140171388A1,BrP(Br)Br.OCCCCCCCCCCc1ccccc1>>BrCCCCCCCCCCc1ccccc1,,CCOCC,,O,,test
US20110309345A1,CC(=O)n1c2ccccc2c2cc(Br)ccc21.c1ccc(-n2c3ccccc3c3ccc4c5ccccc5[nH]c4c32)cc1>>c1ccc(-n2c3ccccc3c3ccc4c5cccc(-c6ccc7[nH]c8ccccc8c7c6)c5[nH]c4c32)cc1,O=[Cu],,,,,test
US05091382,CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](N)[C@H]2SC1.COC(=O)c1ncsc1S>>COC(=O)c1ncsc1SCC1=C(C(=O)O)N2C(=O)C(N)[C@H]2SC1,,O,,O=C([O-])O.[Na+],,test
US20140349972A1,CCOP(C)(=O)c1ccc([C@H](NC(=O)c2cnc(-n3cc(F)cn3)nc2O)c2ccc(F)cc2)cc1>>CP(=O)(O)c1ccc([C@H](NC(=O)c2cnc(-n3cc(F)cn3)nc2O)c2ccc(F)cc2)cc1,,C1COCCO1,,[Na+].[OH-],,test
US04185992,ClCc1ccc(Cl)c(Cl)c1.N#Cc1nc[nH]c1C#N>>N#Cc1ncn(Cc2ccc(Cl)c(Cl)c2)c1C#N,,CN(C)C=O,,O,[H-].[Na+],test
US20130102600A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1cc(-c2ccccc2)sc1N>>CCOC(=O)c1cc(-c2ccccc2)sc1NC(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,,,test
US04029780,CI.O=S1(=O)NC(N2CCNCC2)=Nc2ccc(Cl)cc21>>CN1CCN(C2=Nc3ccc(Cl)cc3S(=O)(=O)N2)CC1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US04250183,CCC(C)(C)N(CCCC(=O)O)C(=O)c1ccc(Cl)cc1.CCOC(=O)CCCNc1c(CC)cccc1CC>>CCc1cccc(CC)c1N(CCCC(=O)O)C(=O)CCCN(C(=O)c1ccc(Cl)cc1)C(C)(C)CC,,CCO,,[K+].[OH-],,test
US20100130495A1,CC(C)(C)OC(=O)N1CCc2c(nc(Nc3ccc(-c4cnco4)cc3)nc2NCc2ccccc2)C1>>c1ccc(CNc2nc(Nc3ccc(-c4cnco4)cc3)nc3c2CCNC3)cc1,,CO,,Cl,,test
US20160039811A1,CCOC(=O)c1c(Br)nn(C)c1Br.CN1CCCC1=O>>C1CC2CNCCN2C1,,CN1CCCC1=O,,,,test
US20060293349A1,CON(C)C(=O)c1c(Cl)ccc(Cl)c1N.[Li]C>>CC(=O)c1c(Cl)ccc(Cl)c1N,,C1CCOC1,O,,,test
US20050261291A1,C1CCOC1.CC(=O)O.CCOC(C)=O.COc1ccc(N2CCNCC2)c(C2CC(C)(C)CC(C)(C)C2)c1>>COc1ccc(N2CCN(CC3CCOCC3)CC2)c(C2CC(C)(C)CC(C)(C)C2)c1,,CCOC(C)=O,,O=C([O-])O.[Na+],,test
US20090281079A1,CC1(C)C(=O)N(Br)C(=O)N1Br.Nc1ncnn2c(CN3CCOCC3)c(Cl)cc12>>Nc1ncnn2c(CN3CCOCC3)c(Cl)c(Br)c12,,CN(C)C=O,,,,test
US20120245124A1,CC(C)[C@H](CO)NCc1cccc(Br)n1.CC1(C)OB(c2ccc([Si](C)(C)C(C)(C)C)s2)OC1(C)C>>CC(C)[C@H](CO)NCc1cccc(-c2ccc([Si](C)(C)C(C)(C)C)s2)n1,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100278733A1,CCN(CC)S(F)(F)F.CN(C)c1ccc(/C=C/C(=O)c2ccc(OCCO)cc2)cc1>>CN(C)c1ccc(/C=C/C(=O)c2ccc(OCCF)cc2)cc1,,COCCOC,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20060148858A1,COC(=O)CCc1cn(-c2ccc(Cl)cn2)nc1C(C)(C)C>>CC(C)(C)c1nn(-c2ccc(Cl)cn2)cc1CCCO,,C1CCOC1,CCCCCC,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20040072818A1,Clc1ccc2c(N3CCNCC3)ccnc2c1.N#CN=C(Oc1ccccc1)Oc1ccccc1>>N#CN=C(Oc1ccccc1)N1CCN(c2ccnc3cc(Cl)ccc23)CC1,,C1CCOC1,CCOCC,,,test
US20150329542A1,CCc1cc(OCOCC[Si](C)(C)C)ccc1-c1cc2c(cnn2COCC[Si](C)(C)C)c[n+]1[O-]>>CCc1cc(OCOCC[Si](C)(C)C)ccc1-c1cc2c(cnn2COCC[Si](C)(C)C)c(O)n1,,C1CCOC1,,CC(=O)OC(C)=O,,test
US20070135631A1,CC(C)(C)[S@@](=O)N[C@](Cc1nnn(C(c2ccccc2)(c2ccccc2)c2ccccc2)n1)(c1ccc(F)cc1)c1cc(F)cc(OC(F)(F)C(F)F)c1>>N[C@](Cc1nn[nH]n1)(c1ccc(F)cc1)c1cc(F)cc(OC(F)(F)C(F)F)c1,,C1COCCO1,CO,Cl,,test
US05461050,CN=C=S.COC(CN)OC>>CNC(=S)NCC(OC)OC,,C1CCOC1,,,,test
US20030114683A1,CCOC(=O)C(=O)OCC.COc1ccccc1OC>>CCOC(=O)C(=O)c1cccc(OC)c1OC,,CCCCCC,CCOCC,[Li]CCCC,[Cl-].[NH4+],test
US05130318,CC(=O)Cl.Cc1cc(OCc2ccc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc2)c(CN)c(C)n1>>CC(=O)NCc1c(OCc2ccc(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)cc2)cc(C)nc1C,,ClCCl,,CCN(CC)CC,O,test
US20140200344A1,C[Si](C)(C)CCOCn1ccc2c3c(cnc21)CNC(=O)N3C1CCNCC1.O=S(=O)(Cl)Cc1ccccc1>>C[Si](C)(C)CCOCn1ccc2c3c(cnc21)CNC(=O)N3C1CCN(S(=O)(=O)Cc2ccccc2)CC1,,ClCCl,,CCN(CC)CC,O,test
US04720500,COc1ccccc1-c1cc2cccnc2nc1N.O=C(O)c1cccc(Br)c1>>COc1ccccc1-c1ccc2ccc(NC(=O)c3cccc(Br)c3)nc2n1,,O,,CO,,test
US20150274704A1,CN(c1nc(Nc2cnn(C)c2)ncc1Cl)C1CC2CN(C(=O)OC(C)(C)C)CC2C1>>CN(c1nc(Nc2cnn(C)c2)ncc1Cl)C1CC2CNCC2C1,,ClCCl,,CCOC(C)=O,Cl,test
US20140179666A1,CC(C)[Si](OS(=O)(=O)C(F)(F)F)(C(C)C)C(C)C.CC1(C)CNc2cc(Br)c(F)cc21>>CC(C)[Si](C(C)C)(C(C)C)N1CC(C)(C)c2cc(F)c(Br)cc21,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070054916A1,Cc1ccc(N)cc1-c1ccc2nc(N)ncc2c1.O=C(Cl)Oc1cccc(C(F)(F)F)c1>>Cc1ccc(NC(=O)Oc2cccc(C(F)(F)F)c2)cc1-c1ccc2nc(N)ncc2c1,,ClCCl,,CCN(CC)CC,,test
US20090181942A1,CC(=O)O.COC(=O)CC[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2-n2c(C#N)ccc21>>COC(=O)CC[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2-n2c(C=O)ccc21,,c1ccncc1,,,,test
US20150218160A1,CC(C)[C@H]1c2ncc(C(=O)O)cc2CN1C(=O)OC(C)(C)C.CCS(=O)(=O)c1ccc(CN)cc1>>CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3c(c2)CN(C(=O)OC(C)(C)C)[C@H]3C(C)C)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040106642A1,CC(C)(C)C(=O)Cl.Cc1cn2ccc3c(c2n1)N[C@H](c1ccccc1)[C@@H](O)C3=O>>Cc1cn2ccc3c(c2n1)N[C@H](c1ccccc1)[C@@H](OC(=O)C(C)(C)C)C3=O,,ClCCl,,CCN(CC)CC,CN(C)c1ccccn1,test
US20140256782A1,C=C[Mg]Br.CC1(C)C=C(C=O)CCC1>>C=CC(O)C1=CC(C)(C)CCC1,,C1CCOC1,,,,test
US07202239B2,COC(=O)c1ccc2c(c1)NCc1cccn1C2.O=C(Cl)c1ccc(C2CCCCC2)cc1>>COC(=O)c1ccc2c(c1)N(C(=O)c1ccc(C3CCCCC3)cc1)Cc1cccn1C2,,ClCCCl,,CCN(CC)CC,,test
US20110021494A1,CCOC(=O)c1cc2c(s1)CCN(S(=O)(=O)c1ccc(C)cc1)C2>>Cc1ccc(S(=O)(=O)N2CCc3sc(C(=O)O)cc3C2)cc1,,CCO,,[Na+].[OH-],,test
US20020165241A1,COc1ccc(CNc2nc(C)cc(NCC3CCN(C(=O)OCc4ccccc4)CC3)n2)c(OC)c1>>Cc1cc(NCC2CCN(C(=O)OCc3ccccc3)CC2)nc(N)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06576596B1,CCON=Cc1c(S(C)(=O)=O)ccc(C(=O)OC)c1Cl>>CCON=Cc1c(S(C)(=O)=O)ccc(C(=O)O)c1Cl,,c1ccncc1,,[I-].[Li+],,test
US04670447,CC(Cl)OC(=O)Cl.CN1CCC(c2nn(-c3ccc(C(F)(F)F)cc3)c3ccc(F)cc23)CC1>>Cl.Fc1ccc2c(c1)c(C1CCNCC1)nn2-c1ccc(C(F)(F)F)cc1,,ClCCCl,,,,test
US20140371199A1,C1COCCN1.O=C(O)c1ccc(-c2cn3c(I)cnc3cn2)cc1>>O=C(c1ccc(-c2cn3c(I)cnc3cn2)cc1)N1CCOCC1,,CN(C)C=O,O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070254908A1,C=CCBr.CCCCc1nc(-c2ccc(C(F)(F)F)cc2)sc1Cn1ccc2cc(O)cnc21>>C=CCOc1cnc2c(ccn2Cc2sc(-c3ccc(C(F)(F)F)cc3)nc2CCCC)c1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20160152609A1,CCOC(=O)c1nc(Br)n2c1CCc1cc(OC)c(OC(C)C)cc1-2>>CCOC(=O)c1nc(Br)n2c1CCc1cc(OC)c(O)cc1-2,,ClCCl,,ClB(Cl)Cl,,test
US20050107449A1,CCOC(=O)C(C)c1nc(-c2ccc(-c3ccccc3F)nc2)sc1C>>Cc1sc(-c2ccc(-c3ccccc3F)nc2)nc1C(C)CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04218458,CCn1cc(-c2ccc(O)cc2)nc1S>>CCn1cnc(-c2ccc(O)cc2)c1,[Ni],CCO,,[NH4+].[OH-],,test
US20160046647A1,Cc1c(CN2CCC(Nc3ncnc4sc(CC(F)(F)F)cc34)CC2)ccc2c1cc(C#N)n2CCN1CCN(C(=O)OC(C)(C)C)CC1>>Cc1c(CN2CCC(Nc3ncnc4sc(CC(F)(F)F)cc34)CC2)ccc2c1cc(C#N)n2CCN1CCNCC1,,CC#N,,Cl[Sn](Cl)(Cl)Cl,,test
US20150080549A1,CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)[C@@H]1CSCN1C(=O)OC(C)(C)C)C(=O)O.N#CCBr>>CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)[C@@H]1CSCN1C(=O)OC(C)(C)C)C(=O)OCC#N,,CC#N,,CCN(C(C)C)C(C)C,,test
US20150011546A1,CO.C[O-].Cc1cc(Cl)c(C#N)c(Cl)n1>>COc1cc(C)nc(OC)c1C#N,,CO,,CC(=O)O,,test
US20160200719A1,Clc1ccc(C(c2ccc(Cl)cc2)c2ccc3nncc(NC4CCNCC4)c3c2)cc1.O=C(O)c1ccc(S(=O)(=O)Cl)cc1>>O=C(O)c1ccc(S(=O)(=O)N2CCC(Nc3cnnc4ccc(C(c5ccc(Cl)cc5)c5ccc(Cl)cc5)cc34)CC2)cc1,,ClCCl,,CCN(CC)CC,,test
US04051148,COC(=O)c1ccc(C=O)cc1SCc1ccccc1>>O=Cc1ccc(C(=O)O)c(SCc2ccccc2)c1,,CO,O,CC(=O)O,[K+].[OH-],test
US20100317647A1,CCOC(=O)[C@@H]1CC(O[Si](C)(C)C(C)(C)C)C[C@H]1CO.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOC(=O)[C@@H]1CC(O[Si](C)(C)C(C)(C)C)C[C@H]1COS(=O)(=O)c1ccc(C)cc1,,ClCCl,,CCN(CC)CC,,test
US20100256156A1,Br[Mg]C1CCC2(CC1)OCCO2.Cc1oc(-c2ccccc2)cc1C=O>>Cc1oc(-c2ccccc2)cc1C(O)C1CCC2(CC1)OCCO2,,C1CCOC1,,Cl,O,test
US05698575,COc1ccc2c(=O)c(I)coc2c1.c1ccc2[nH]ncc2c1>>COc1ccc2c(=O)cc(-c3n[nH]c4ccccc34)oc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160175289A1,C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(NC3CN(C(=O)OC(C)(C)C)C3)cc2F)N1CC(C)(C)F>>C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(NC3CNC3)cc2F)N1CC(C)(C)F,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20100240580A1,Fc1ccccc1C(F)(F)F.Oc1ccc(Br)cc1>>FC(F)(F)c1ccccc1Oc1ccc(Br)cc1,,CS(C)=O,O,[K+].[OH-],,test
US20050234101A1,C#Cc1ccc(-c2ccc(Cl)cc2)cn1.COC(=O)c1cc2cc(I)ccc2s1>>COC(=O)c1cc2cc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)ccc2s1,[Cu]I,C1CCOC1,,CCN(CC)CC,CCOC(C)=O,test
US20160009683A1,CCOC(=O)C(F)(F)c1ccccc1OCC(F)(F)F>>O=C(O)C(F)(F)c1ccccc1OCC(F)(F)F,,C1CCOC1,O,CO,[Li+].[OH-],test
US20090325929A1,C1CNCCN1.O=[N+]([O-])c1ccc(Br)cc1>>O=[N+]([O-])c1ccc(N2CCNCC2)cc1,[Cu]I,CC(C)O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US04297499,C=CCCCCCCCCCC.Cl[SiH2]Cl>>CCCCCCCCCCCC[SiH](Cl)Cl,Cl[Ni]Cl,,,,,test
US20070167433A1,CC(C)[Si](OC1CN(C(=O)OCc2ccccc2)CC(O)C1c1ccc(O)cc1)(C(C)C)C(C)C.COS(=O)(=O)OC>>COc1ccc(C2C(O)CN(C(=O)OCc3ccccc3)CC2O[Si](C(C)C)(C(C)C)C(C)C)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06951864B2,CCCc1c(Cl)ncnc1Cn1ccnc1-c1cccc(F)n1.CO>>CCCc1c(Cn2ccnc2-c2cccc(F)n2)ncnc1OC,,CO,,CC(=O)O,C[O-].[Na+],test
US20060052599A1,CCOC(=O)/C(F)=C/c1cnc(N[C@@H]2CCCN(CC3CCCCC3)C2)c(Cl)c1>>O=C(O)/C(F)=C/c1cnc(N[C@@H]2CCCN(CC3CCCCC3)C2)c(Cl)c1,,CO,,[Na+].[OH-],,test
US04220795,CCC1CC(C)(C(=O)C=CO)C1.O=S(Cl)Cl>>CCC1CC(C)(C(=O)/C=C/Cl)C1,,c1ccccc1,,,,test
US20100305133A1,CCOC(=O)CNC(=O)c1c(O)c(-c2cc3ccccc3s2)cc2nccnc12>>O=C(O)CNC(=O)c1c(O)c(-c2cc3ccccc3s2)cc2nccnc12,,CCO,,[Na+].[OH-],,test
US04956465,CCOC(=O)c1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O.N#CCC#N>>CCOC(=O)c1cn(C2CC2)c2c(F)c(C(C#N)C#N)c(F)cc2c1=O,,C1COCCO1,,Cl,CC(C)(C)[O-].[K+],test
US20090054465A1,COC(=O)/C=C/c1cnc(N[C@@H]2CCCN(CCCc3ccccc3)C2)cn1>>O=C(O)/C=C/c1cnc(N[C@@H]2CCCN(CCCc3ccccc3)C2)cn1,,CO,,Cl,[Na+].[OH-],test
US20100093694A1,CC(C)/C(N)=N/O.CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cccc(C(=O)OC)c3)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cccc(-c4nc(C(C)C)no4)c3)cc12,,CCO,,C[O-].[Na+],,test
US20070004736A1,CC(C)(C)OC(=O)N1CCC(NCCO)CC1.Cc1nc(C(=O)O)c[nH]1>>Cc1nc(C(=O)N(CCO)C2CCN(C(=O)OC(C)(C)C)CC2)c[nH]1,,CC#N,CCN(CC)CC,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20100094005A1,NC(=O)CCl.O=c1cc(CCN2CCN(c3nccc4sccc34)CC2)c2ccc(F)cc2[nH]1>>NC(=O)Cn1c(=O)cc(CCN2CCN(c3nccc4sccc34)CC2)c2ccc(F)cc21,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20040106616A1,N#C[Cu].O=[N+]([O-])c1cc(Br)ccc1Br>>N#Cc1ccc(Br)cc1[N+](=O)[O-],,CC(=O)N(C)C,CCOC(C)=O,,,test
US20040092737A1,CCOC(=O)CP(=O)(OCC)OCC.C[C@@H]1C[C@@H](C)C2CN(C)CC1C2=O>>CCOC(=O)C=C1C2CN(C)CC1[C@H](C)C[C@H]2C,,C1CCOC1,,CCOC(C)=O,[H-].[Na+],test
US20160052888A1,COc1ccc2c(c1)C(C)(C)N(CCCc1ccccc1)C2=O>>CC1(C)c2cc(O)ccc2C(=O)N1CCCc1ccccc1,,ClCCl,,BrB(Br)Br,,test
US20050209338A1,C#CCCOCCCCCCN1C[C@@H](c2ccc3c(c2)COC(C)(C)O3)OC1=O.Nc1cccc(I)c1>>CC1(C)OCc2cc([C@@H]3CN(CCCCCCOCCC#Cc4cccc(N)c4)C(=O)O3)ccc2O1,,CCN(CC)CC,,CC#N,,test
US20090286778A1,COc1ccc(N)cc1I.Clc1ncc(Cl)c(Cl)n1>>COc1ccc(Nc2nc(Cl)ncc2Cl)cc1I,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040198793A1,CCCCCCCCCC(=O)Cl.COc1ccc(OC)c(Cl)c1>>CCCCCCCCCC(=O)c1cc(OC)c(Cl)cc1OC,Cl[Ti](Cl)(Cl)Cl,ClCCl,,Cl,,test
US05541324,C1CCNC1.Fc1ccc(-c2ncn3c2CNc2ccccc2-3)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=C(N1CCCC1)N1Cc2c(-c3ccc(F)cc3)ncn2-c2ccccc21,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040198784A1,CSc1cc(S(N)(=O)=O)sc1[Si](C)(C)C>>CSc1csc(S(N)(=O)=O)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080227770A1,CCOC(=O)CC(=O)CNC(=O)OC(C)(C)C.Cl>>CCOC(=O)CC(=O)CN.Cl,,CC(=O)O,CCOC(C)=O,,,test
US04163062,Clc1ccc(NN=Cc2ccccc2)cc1.O=CO>>O=CN(N=Cc1ccccc1)c1ccc(Cl)cc1,,COCCOC,,CC(=O)OC(C)=O,,test
US06169107A,CCOC(=O)c1cc2c(C)ccc(O)c2n1C.CN(C)C=O>>CCOC(=O)c1cc2c(C)ccc(OC)c2n1C,,CN(C)C=O,,[I-].[K+],,test
US06376491B1,CCOC(=O)c1cc2cc(OCc3oc4cccc(OCCCNCc5cccnc5)c4c3C)ccc2o1>>Cc1c(COc2ccc3oc(CO)cc3c2)oc2cccc(OCCCNCc3cccnc3)c12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090054376A1,CCCCCCC(C)(C)c1cc(O)cc(O)c1.OC1C=CCCC1>>CCCCCCC(C)(C)c1cc(O)c(C2C=CCCC2)c(O)c1,,ClCCl,,CS(=O)(=O)O,,test
US20080207902A1,CCOC(=O)c1c(C(F)(F)C(F)(F)F)nn2c(OC)ccc(CO)c12>>COc1ccc(CO)c2cc(C(F)(F)C(F)(F)F)nn12,,CO,,[K+].[OH-],,test
US04281017,O=C(O)Cc1ccc(C(CC(=O)O)c2ccccc2)cc1>>O=C(O)Cc1ccc(C2CC(=O)c3ccccc32)cc1,,O,,,,test
US06156700,COS(=O)(=O)OC.Cn1c(C(F)(F)F)cc(=O)n(-c2ccc3snc(C(=O)NS(C)(=O)=O)c3c2)c1=O>>CN(C(=O)c1nsc2ccc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)cc12)S(C)(=O)=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140080808A1,CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(C3(c4ccc(B5OC(C)(C)C(C)(C)O5)cc4)CC3)n2CCS1.Clc1cccnc1Br>>CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(C3(c4ccc(-c5ncccc5Cl)cc4)CC3)n2CCS1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20070275907A1,CCc1ccc(Cc2cc3c(cc2Cl)C(O)C[C@]32O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1>>CCc1ccc(Cc2cc3c(cc2Cl)C(=O)C[C@]32O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04831041,CI.Cc1nc2c(OCc3ccccc3C#N)cccn2c1CN(C)C>>Cc1nc2c(OCc3ccccc3C#N)cccn2c1C[N+](C)(C)C.[I-],,ClC(Cl)Cl,,CC(C)=O,,test
US20140179680A1,O=C(CCl)N(Cc1ccccc1)[C@@H]1COC[C@H]1O>>O=C1CO[C@@H]2COC[C@H]2N1Cc1ccccc1,,CC(C)(C)O,,CC(C)(C)[O-].[K+],,test
US20140315963A1,Nc1cc(OC(F)(F)F)ccc1O.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2cc(OC(F)(F)F)ccc2o1,,C1COCCO1,,,,test
US06235789B1,CCOC(=O)CCc1cc(C)c(OC)c(Br)c1>>COc1c(C)cc(CCC(=O)O)cc1Br,,CO,,Cl,[Na+].[OH-],test
US20130217680A1,COc1cc(CC(=O)O)ccc1OC(C)=O.O=C1CCC(=O)N1Cl>>COc1cc(CC(=O)O)c(Cl)cc1OC(C)=O,,CN(C)C=O,,O,,test
US20030130213A1,C=CCO.N#Cc1nc(F)cnc1F>>C=CCOc1ncc(F)nc1C#N,,CS(C)=O,O,CCN(CC)CC,Cc1ccccc1,test
US20080051395A1,CN(C)CCOc1cccc(N)c1.O=C(Nc1cccc(-c2nn3cc(F)ccc3c2-c2ccnc(Cl)n2)c1)c1c(F)cccc1F>>CN(C)CCOc1cccc(Nc2nccc(-c3c(-c4cccc(NC(=O)c5c(F)cccc5F)c4)nn4cccc(F)c34)n2)c1,Cl,CC(C)O,,,,test
US20040235919A1,COC(=O)C(C)c1ccc(N2CCNC2=O)cc1>>CC(C(=O)O)c1ccc(N2CCNC2=O)cc1,,CO,,O=C([O-])[O-].[Na+].[Na+],,test
US20070254869A1,CC(=O)Cl.CC(C)(C)OC(=O)N1CCCC(NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccc(Cl)cc21>>CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(C(=O)OC(C)(C)C)c2cc(Cl)ccc21,,ClCCl,,c1ccncc1,,test
US20100004269A1,CCON.COC(=O)c1ncc2cncn2c1Nc1ccc(I)cc1F>>CCONC(=O)c1ncc2cncn2c1Nc1ccc(I)cc1F,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20120252853A1,CI.N#Cc1ccc2c(ccn2S(=O)(=O)c2ccccc2)c1>>Cc1cc2cc(C#N)ccc2n1S(=O)(=O)c1ccccc1,,C1CCOC1,CCOC(C)=O,CC(C)[N-]C(C)C.[Li+],,test
US20080085910A1,Clc1ncccn1.Nc1ccc(I)cc1>>Ic1ccc(Nc2ncccn2)cc1,,C1COCCO1,,CC(=O)O,O=C([O-])O.[Na+],test
US06274120B1,CC(Cl)OC(=O)Cl.CCCCCCCCCCCCCCCCCCO>>CCCCCCCCCCCCCCCCCCOC(=O)OC(C)Cl,,ClC(Cl)Cl,,c1ccncc1,,test
US20090149448A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC[C@H]1CN(Cc2ccccc2)CCN1>>CC[C@H]1CN(Cc2ccccc2)CCN1C(=O)OC(C)(C)C,,ClCCl,,,,test
US04965257,C#Cc1ccc(C23OCC(CCC)(CO2)CO3)cc1.CC(C)(C)[Si](C)(C)Cl>>CCCC12COC(c3ccc(C#C[Si](C)(C)C(C)(C)C)cc3)(OC1)OC2,,C1CCOC1,,[Li]CCCC,,test
US20040235836A1,CCOC(=O)CC(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1N>>CCOC(=O)Cc1nc2cc(C(F)(F)F)cc(C(F)(F)F)c2[nH]1,,C1CCOC1,CC(=O)O,,,test
US20050096309A1,CN(C)Cc1nccn1-c1ccc(N)c(F)c1.ClCCl.O=C=Nc1cccc(Cl)c1>>CN(C)Cc1nccn1-c1ccc(NC(=O)NCCCCl)c(F)c1,,ClCCl,,,,test
US05576324,Cc1cc2c(c3c1NC(=O)CC3)OC(CN)C2.N#CBr>>Cc1cc2c(c3c1NC(=O)CC3)OC(CNC#N)C2,,C1CCOC1,,,,test
US20060084645A1,C1COCCN1.CC(=O)c1cccc(-c2nc(Cl)cc(Nc3ccc(OC(F)(F)F)cc3)n2)c1>>CC(=O)c1cccc(-c2nc(Nc3ccc(OC(F)(F)F)cc3)cc(N3CCOCC3)n2)c1,,CCCCO,,,,test
US05286728,CC(C)OCCNc1ccc(C(=O)N2CCN(CCc3ccc(Cl)cc3)CC2)cc1.COCC(=O)Cl>>COCC(=O)N(CCOC(C)C)c1ccc(C(=O)N2CCN(CCc3ccc(Cl)cc3)CC2)cc1.Cl,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20050004391A1,ClCCOCCl.OC1C2CC3CC(C2)CC1C3>>ClCCOCOC1C2CC3CC(C2)CC1C3,,C1CCOC1,,CCN(CC)CC,,test
US20090227588A1,COCCn1cc(C(=O)Cl)ccc1=O.Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)nc1>>COCCn1cc(C(=O)Nc2ccc(-n3nc(-c4cccnc4)cc3C(F)(F)F)nc2)ccc1=O,,c1ccncc1,,,,test
US20140275027A1,COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCN(C(=O)[C@H]4C[C@@H](O)CN4C(=O)OC(C)(C)C)CC3)cc12>>COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCN(C(=O)[C@H]4C[C@@H](O)CN4)CC3)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150239842A1,CC1(C)OB(c2cc(F)c(Cl)c(C(=O)[O-])c2)OC1(C)C.COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)ccc1Cl.Cn1cc(Br)cn1>>COC(=O)c1cc(-c2cnn(C)c2)cc(F)c1Cl,,C1COCCO1,,[Cs+].[F-],,test
US05114925,CCOC(=O)CS(=O)(=O)C[C@H](O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C.NCCN1CCOCC1>>CC(C)(C)OC(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CS(=O)(=O)CC(=O)NCCN1CCOCC1,,CCOC(C)=O,,CO,ClC(Cl)Cl,test
US20060030612A1,C=CCBr.COc1ccc(-c2n[nH]c3c(C(F)(F)F)cccc23)c(OC)c1>>C=CCn1nc2c(C(F)(F)F)cccc2c1-c1ccc(OC)cc1OC,,CN(C)C=O,,[H-].[Na+],,test
US20040006081A1,CC(C)(C)OC(=O)NC1CCNCC1.O=CCC(c1ccc(F)cc1)c1ccc(F)cc1>>CC(C)(C)OC(=O)NC1CCN(CCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1,,CC(Cl)Cl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20080300242A1,COc1cc(C2=CCC3(CC2)OCCO3)ccc1[N+](=O)[O-]>>COc1cc(C2=CCC(=O)CC2)ccc1[N+](=O)[O-],,ClCCl,,O=C(O)C(F)(F)F,,test
US20160137587A1,C1CCOC1.C1COCCOCCOCCOCCOCCO1.C[Si](C)(C)c1ccccc1OS(=O)(=O)C(F)(F)F.c1ccc2c(c1)CCNC2>>C=Cc1ccccc1CN(c1ccccc1)c1ccccc1,,C1CCOC1,,[F-].[K+],,test
US08697725B2,CC(=O)N1c2ccc(B3OC(C)(C)C(C)(C)O3)cc2C(NC(=O)OC(C)C)CC1C.CC(=O)N1c2ccc(B3OC(C)(C)C(C)(C)O3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C.CN(C)CCn1cc(Br)cn1.Cl>>CC(=O)N1c2ccc(-c3cnn(CCN(C)C)c3)cc2[C@H](N(C(=O)O)C(C)C)C[C@@H]1C.Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,CO,O=C([O-])[O-].[K+].[K+],test
US05834486,CC(C)(C)OC(=O)NCCCN(CCc1ccccn1)C(=O)OC(C)(C)C.CCN(CCCBr)C(=O)OC(C)(C)C>>CCN(CCCN(CCCN(CCc1ccccn1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,C1COCCO1,,O,[H-].[Na+],test
US20150087825A1,C=C(CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)CC(C)(NS(=O)C(C)(C)C)c1cc(Br)cs1>>C=C(CO)CC(C)(N)c1cc(Br)cs1,,CO,ClCCl,Cl,,test
US06083959,CNC(=O)c1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(Cl)c(CBr)c2Cl)cc1.Cc1cc(-n2ccnc2)c2cccc(O)c2n1>>CNC(=O)c1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(-n5ccnc5)cc(C)nc34)c2Cl)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090054435A1,CC(Br)C(=O)[O-].Cc1oc(-c2ccccc2)nc1COc1ccc(C(=O)c2ccccc2O)cc1>>Cc1oc(-c2ccccc2)nc1COc1ccc(C(=O)c2ccccc2OC(C)C(=O)O)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20160229816A1,CC(=O)OCCl.N#Cc1[nH]nnc1-c1cc(-c2ccsc2)cc(C(F)(F)F)c1>>CC(=O)OCn1nc(C#N)c(-c2cc(-c3ccsc3)cc(C(F)(F)F)c2)n1,,CN(C)C=O,,O,[H-].[Na+],test
US20020002169A1,CC(C)(C)n1nc(-c2ccc(OCc3ccccc3)cc2)c(C(N)=O)c1N>>CC(C)(C)n1nc(-c2ccc(O)cc2)c(C(N)=O)c1N,[Pd],C1CCOC1,CO,O=C[O-].[NH4+],,test
US06048864,COc1ccc(C#N)c(O)c1OC.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>COc1ccc(C#N)c(OCC(F)(F)F)c1OC,,CN(C)C=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20110118230A1,II.O=C(O)c1ccc(Br)nc1>>O=C(O)c1cnc(Br)cc1I,,C1CCOC1,,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US20120197027A1,COc1cc2c(Cl)ncnc2cc1OCCCn1cncn1.Cl.Nc1ccc2[nH]ccc2c1>>COc1cc2c(Nc3ccc4[nH]ccc4c3)ncnc2cc1OCCCn1cncn1.Cl,,CC(C)O,,,,test
US20060226768A1,Brc1c2ccccc2c(Br)c2ccccc12.Cl[Si](c1ccccc1)(c1ccccc1)c1ccccc1>>Brc1c2ccccc2c([Si](c2ccccc2)(c2ccccc2)c2ccccc2)c2ccccc12,,C1CCOC1,,[Li]CCCC,,test
US20040157149A1,Cc1ccc(S(=O)(=O)NN=CC(=O)O)cc1.O=S(Cl)Cl>>Cc1ccc(S(=O)(=O)NN=CC(=O)Cl)cc1,,c1ccccc1,,Cl,,test
US20070270411A1,COc1ccc(N(C(=O)CN2C=CN(c3ccccc3)C(=O)C(=CO)C2=O)C(C)C)cc1.CS(=O)(=O)Cl>>COc1ccc(N(C(=O)CN2C=CN(c3ccccc3)C(=O)C(=COS(C)(=O)=O)C2=O)C(C)C)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20060100262A1,CN(C)CCN.COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(=O)COc1ccccc1-3>>COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(NCCN(C)C)COc1ccccc1-3,,CCOC(C)=O,ClCCCl,CC(=O)O,[Na+].[OH-],test
US20040180898A1,CCOC(=O)C(Nc1cc(NC(=O)OC(C)(C)C)cc(Cl)n1)OC.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>CCOC(=O)c1cncn1-c1cc(NC(=O)OC(C)(C)C)cc(Cl)n1,,CCO,,O,O=C([O-])[O-].[K+].[K+],test
US05883106,COc1cccc(C2(C#N)CCC2)c1>>N#CC1(c2cccc(O)c2)CCC1,,ClCCl,,BrB(Br)Br,,test
US04925863,CCC(Oc1ccc(C=Cc2nc[nH]n2)cc1)C(=O)OC.N>>CCC(Oc1ccc(C=Cc2nc[nH]n2)cc1)C(N)=O,,CC(C)=O,,CCO,,test
US20050014740A1,Cc1ccc(Sc2ccccc2C2(O)CCN(C(=O)OC(C)(C)C)CC2)cc1>>Cc1ccc(Sc2ccccc2C2=CCNCC2)cc1,,CC(=O)O,,Cl,[Na+].[OH-],test
US05459270,BrCc1ccccc1.FC(F)(F)c1cc(CO[C@H]2CCCN[C@H]2c2ccccc2)cc(C(F)(F)F)c1>>FC(F)(F)c1cc(CO[C@H]2CCCN(Cc3ccccc3)[C@H]2c2ccccc2)cc(C(F)(F)F)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070167443A1,CCOC(=O)c1cn(Cc2cccc(Br)n2)c2ccccc2c1=O>>O=C(O)c1cn(Cc2cccc(Br)n2)c2ccccc2c1=O,,CO,O,Cl,[Li+].[OH-],test
US20090156642A1,CN(Cc1cc(Sc2cccnc2)cs1)C(=O)OC(C)(C)C.O=C1CCC(=O)N1Br>>CN(Cc1cc(Sc2cccnc2)c(Br)s1)C(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US05164397,CN(CCCl)C(c1ccccc1)(c1ccccc1)c1ccccc1.c1ccc(N2CCNCC2)c(C2CC2)c1>>CN(CCN1CCN(c2ccccc2C2CC2)CC1)C(c1ccccc1)(c1ccccc1)c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04181802,COc1ccccc1OCC1CO1.O=c1[nH]c2ccc(Cl)cc2n1CC1CCCNC1>>COc1ccccc1OCC(O)CN1CCCC(Cn2c(=O)[nH]c3ccc(Cl)cc32)C1,,CC(C)O,,,,test
US20150291640A1,CCOC(=O)C(O[C@H]1C=C[C@@H](n2cc(C)c(=O)[nH]c2=O)C1)P(=O)(OCC)OCC>>CCOC(=O)C(O[C@H]1CC[C@@H](n2cc(C)c(=O)[nH]c2=O)C1)P(=O)(OCC)OCC,[Pd],CCO,,,,test
US20040138065A1,N#CCC#N.O=Cc1cccc(Br)c1>>N#CC(C#N)Cc1cccc(Br)c1,,CCO,O,Cl,[BH4-].[Na+],test
US20060211717A1,COc1cc2nccc(Oc3ccc(N)c(C)c3C)c2cc1OC.Cc1ccc(SCCCO)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)OCCCSc4ccc(C)cc4)c(C)c3C)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US04859229,Cn1c(C(F)(F)F)cc(=O)n(-c2cc(O)c(Cl)cc2F)c1=O.O=S(=O)(Cl)Cl>>Cn1c(C(F)(F)F)cc(=O)n(-c2cc(OS(=O)(=O)Cl)c(Cl)cc2F)c1=O,,ClCCl,,c1ccncc1,,test
US20080096921A1,COC(=O)c1cc2ccc(-c3ccc(O)cc3)cc2cn1.Cc1cccc(C)c1OCc1noc(C(C)C)c1CO>>COC(=O)c1cc2ccc(-c3ccc(OCc4c(COc5c(C)cccc5C)noc4C(C)C)cc3)cc2cn1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100204276A1,CC(=O)NCCc1cn(S(=O)(=O)c2ccc(C)cc2)c2ccc(OCCN3CCCCC3)cc12>>CC(=O)NCCc1c[nH]c2ccc(OCCN3CCCCC3)cc12,,CO,,[Mg],,test
US20080293709A1,C[Si](C)(C)Cl.Cc1ccsc1C#N>>Cc1cc([Si](C)(C)C)sc1C#N,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20040138269A1,Cc1ccc(S(=O)(=O)n2cc(-c3cccc(N)c3)cc2C(=O)OCc2ccccc2)cc1.O=C=Nc1ccc(C(F)(F)F)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3cccc(NC(=O)Nc4ccc(C(F)(F)F)cc4)c3)cc2C(=O)OCc2ccccc2)cc1,,ClCCl,,,,test
US05990142,CCOC(=O)c1cc(=O)c2cccc([N+](=O)[O-])c2o1.N>>NC(=O)c1cc(=O)c2cccc([N+](=O)[O-])c2o1,,C1CCOC1,CCO,,,test
US20060148858A1,CCOC(=O)CCc1cc(O)nn1-c1ccccc1.Cc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO>>Cc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCOc1cc(CCC(=O)O)n(-c2ccccc2)n1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20100197609A1,CC[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)OCCOc1ccc(-c2c(C#N)c(SCc3csc(-c4ccc(Cl)cc4)n3)nc(N3CCCC3)c2C#N)cc1.Cl>>CC[C@H](C)[C@H](N)C(=O)N[C@@H](C)C(=O)OCCOc1ccc(-c2c(C#N)c(SCc3csc(-c4ccc(Cl)cc4)n3)nc(N3CCCC3)c2C#N)cc1.Cl,,CCOCC,ClCCl,,,test
US20090176778A1,COC(=O)Cc1c(C(=O)O)nc2c(C(F)(F)F)cc(-c3ccoc3)cn12.NCc1cccs1>>COC(=O)Cc1c(C(=O)NCc2cccs2)nc2c(C(F)(F)F)cc(-c3ccoc3)cn12,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150152108A1,CNC.Nc1nccc(Cl)n1>>CN(C)c1ccnc(N)n1,,O,,,,test
US20130143892A1,COC(=O)c1cnc(Cl)cn1.Cc1nc[nH]n1>>Cc1ncn(-c2cnc(C(=O)O)cn2)n1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20030166628A1,CC(Br)C(=O)c1cc2cccc(Cl)c2s1.S=C1NCCN1>>Br.CC1=C(c2cc3cccc(Cl)c3s2)N2CCN=C2S1,,CC(=O)O,,CCO,,test
US20100204119A1,CCCCOC(=O)N1CCC(c2ccc(N3CCOc4ncnc(N)c4C3=O)cc2)CC1>>Nc1ncnc2c1C(=O)N(c1ccc(C3CCNCC3)cc1)CCO2,,ClCCl,,O=C(O)C(F)(F)F,,test
US05510326,CC1=CCC(C2CC(C)(C)OC2C)C1(C)C>>CC1OC(C)(C)CC1C1CCC(C)C1(C)C,[Pd],,,,,test
US20130281428A1,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.Nc1ncc(Br)cc1I>>Nc1ccc(-c2cc(Br)cnc2N)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20050164402A1,C=CCCCCCCCCCOCCOCCOCCOCCOCCOCCO.CC(C)(C)OC(=O)CBr>>C=CCCCCCCCCCOCCOCCOCCOCCOCCOCCOCC(=O)OC(C)(C)C,,CCOC(C)=O,,CN(C)C=O,[H-].[Na+],test
US20150166558A1,CCOC(=O)C1=C(NC(N)=O)CCC12CCN(Cc1ccccc1)CC2>>O=c1[nH]c2c(c(=O)[nH]1)C1(CC2)CCN(Cc2ccccc2)CC1,,CCO,,Cl,[Na+].[OH-],test
US20160120841A1,CCOC(=O)c1cnc([C@@H]2C[C@H](NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c3ccccc3O2)s1>>O=C(O)c1cnc(C2C[C@H](NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c3ccccc3O2)s1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20050054696A1,CN(C)c1cccc(C(=O)NNC(=O)c2cc3cc(Cl)ccc3[nH]2)c1.CS(=O)(=O)O>>CN(C)c1cccc(C(=O)NNC(=O)c2cc3cc(Cl)ccc3[nH]2)c1.CS(=O)(=O)O,,CO,,CCOCC,,test
US05882628,CC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>CC(O)c1cc(N)cc(N)c1,[Pd],CO,,,,test
US07169926B1,CCn1ccc2nc(C3CCCC(NC(=O)OCc4ccccc4)C3)[nH]c2c1=O.N#Cc1ccccc1CBr>>CCn1ccc2nc(C3CCCC(NC(=O)OCc4ccccc4)C3)n(Cc3ccccc3C#N)c2c1=O,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150246894A1,NC(=O)CBr.O=C1N[C@@H](c2ccccc2F)C(c2ccc(F)cc2)(c2ccc(F)cc2)O1>>NC(=O)CN1C(=O)OC(c2ccc(F)cc2)(c2ccc(F)cc2)[C@@H]1c1ccccc1F,,C1CCOC1,,Cl,[H-].[Na+],test
US20040209886A1,Cc1c(N)cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c12.O=S(=O)(Cl)c1ccccc1>>Cc1c(NS(=O)(=O)c2ccccc2)cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c12,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20100204196A1,CCOc1cc2c(cc1[N+](=O)[O-])N(C(=O)CN(C)C)CCC2>>CCOc1cc2c(cc1N)N(C(=O)CN(C)C)CCC2,[Pd],CO,,[H][H],,test
US20160095858A1,CC(C)(C)c1ccc(C#N)c(O)n1.O=C1CCC(=O)N1Br>>CC(C)(C)c1nc(O)c(C#N)cc1Br,,ClCCCl,,O,,test
US20110224263A1,CC(=O)N[C@@H]1CCC[C@H]1c1ccc(S(=O)(=O)Cl)cc1.CC(C)c1nnc(N)s1>>CC(=O)N[C@@H]1CCC[C@H]1c1ccc(S(=O)(=O)Nc2nnc(C(C)C)s2)cc1,,c1ccncc1,,,,test
US20070066596A1,CNCCO.N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(Br)c1S(=O)(=O)C(F)(F)F>>CN(CCO)c1c(S(=O)(=O)C(F)(F)F)c(C#N)nn1-c1c(Cl)cc(C(F)(F)F)cc1Cl,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20150336928A1,CC1(O)CCCc2ccccc21.C[Si](C)(C)C#N>>CC1(C#N)CCCc2ccccc21,,ClCCl,,,,test
US20150119390A1,CC(OC1CCCCO1)c1ccc(-c2cccc(CO)c2)nc1.COc1cc(O)c2cc(-c3cn4nc(OC)sc4n3)oc2c1>>COc1cc(OCc2cccc(-c3ccc(C(C)OC4CCCCO4)cn3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1,,C1CCOC1,ClCCl,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20120252770A1,C[C@H](N)[C@H](Oc1ccc2c(cnn2-c2cccnc2)c1)c1ccccc1.O=C(Cl)c1ccco1>>C[C@H](NC(=O)c1ccco1)[C@H](Oc1ccc2c(cnn2-c2cccnc2)c1)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20020111353A1,CSc1nccc(CC(C)=O)n1.NNc1ccccc1>>CSc1nccc(CC(C)=NNc2ccccc2)n1,,CCO,,,,test
US20150297586A1,C1CCC(N2CCNCC2)CC1.ClCCCCn1nnc2ccccc21>>c1ccc2c(c1)nnn2CCCCN1CCN(C2CCCCC2)CC1,,CC#N,,CCN(C(C)C)C(C)C,[I-].[K+],test
US06268365B1,CCC(=O)O.COc1ccc(Cn2cc(Br)c(C)c(N)c2=O)cc1>>CCC(=O)Nc1c(C)c(Br)cn(Cc2ccc(OC)cc2)c1=O,,CN(C)C=O,ClCCl,ClCCCl,On1nnc2cccnc21,test
US20060293350A1,CC=O.COc1cc(Cl)c(C)c(Br)c1NC(=O)OC(C)(C)C>>COc1cc(Cl)c(C)c2c1NC(=O)OC2C,,C1CCOC1,O,[Li]CCCC,[Cl-].[NH4+],test
US20070191336A1,CCOC(=O)Cc1cccc(-n2nc(C(C)(C)C)cc2N)c1.[N-]=C=O.c1ccccc1>>CCOC(=O)Cc1cccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccccc2)c1,,C1CCOC1,,CCN(CC)CC,Cl,test
US20020077329A1,Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(-n3c(C(C)NC(=O)OC(C)(C)C)nc4cc(C(F)(F)F)c(Cl)cc43)cc2)cc1>>CC(=O)NC(C)c1nc2cc(C(F)(F)F)c(Cl)cc2n1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20100216746A1,C[Si](C)(C)CCOCn1cnc(Cl)c1C(=O)O.N#Cc1cc(Oc2c(Cl)ccc(CN)c2F)cc(C(F)(F)F)c1>>C[Si](C)(C)CCOCn1cnc(Cl)c1C(=O)NCc1ccc(Cl)c(Oc2cc(C#N)cc(C(F)(F)F)c2)c1F,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110319378A1,C=CC[C@@]1(COCC[Si](C)(C)C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)CN(C)S(=O)(=O)C2CC2)C1=O>>C=CC[C@@]1(CO)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)CN(C)S(=O)(=O)C2CC2)C1=O,,ClCCl,,FB(F)F,,test
US20060094750A1,CCS(=O)(=O)c1ccc(Cl)c([N+](=O)[O-])c1.NCCOC(F)(F)F>>CCS(=O)(=O)c1ccc(NCCOC(F)(F)F)c([N+](=O)[O-])c1,,CCN(CC)CC,,Cl,,test
US20020065308A1,C[Si](C)(C)N=[N+]=[N-].N#Cc1ccc(CCCN2C(=O)CCC2CCC(O)Cc2ccccc2)cc1>>O=C1CCC(CCC(O)Cc2ccccc2)N1CCCc1ccc(-c2nn[nH]n2)cc1,,Cc1ccccc1,,CCCC[Sn](=O)CCCC,,test
US05420126,C1CC2OC2C1.CC1(C)CNc2cc(C#N)ccc2O1>>CC1(C)CN(C2CCCC2O)c2cc(C#N)ccc2O1,,CN(C)C=O,O,[H-].[Na+],,test
US20100210674A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1Nc2cc(Cl)ccc2/C1=C/c1cccnc1>>CC(C)(C)OC(=O)N1C(=O)/C(=C\c2cccnc2)c2ccc(Cl)cc21,CN(C)c1ccncc1,ClCCl,,,,test
US20120095007A2,CC(=O)Cl.NC(=O)OC(CCN1CCN(c2ccc(O)cc2)CC1)c1ccc(F)cc1>>CC(=O)Oc1ccc(N2CCN(CCC(OC(N)=O)c3ccc(F)cc3)CC2)cc1,,CC(C)=O,O,CCN(CC)CC,,test
US20120114600A1,CC(C)(C)OC(=O)N1CCN(c2ccc(C(=O)O)cc2)CC1>>O=C(O)c1ccc(N2CCNCC2)cc1,,CO,Cl,,,test
US20100204272A1,Cc1ccc(C(=O)O)c([N+](=O)[O-])c1>>Cc1ccc(CO)c([N+](=O)[O-])c1,,C1CCOC1,,,,test
US20160002242A1,CN1CCC(n2cc(Nc3ncc([N+](=O)[O-])c(Nc4ccc5ncccc5c4)n3)cn2)CC1>>CN1CCC(n2cc(Nc3ncc(N)c(Nc4ccc5ncccc5c4)n3)cn2)CC1,[Pd],CO,,,,test
US05750300,COC1CCC(CBr)CC1>>OC1CCC(CBr)CC1,,ClC(Cl)Cl,,C[Si](C)(C)I,,test
US20080161302A1,CC(=O)c1ccc(N)cc1>>CC(O)c1ccc(N)cc1,,CO,,[BH4-].[Na+],,test
US20100004280A1,CN(C)S(=O)(=O)n1cc(CC(C)(C)C)nc1C(=O)Cc1ccc(Br)cc1.Cn1cc(B2OC(C)(C)C(C)(C)O2)c(NC(=O)OC(C)(C)C)n1>>CN(C)S(=O)(=O)n1cc(CC(C)(C)C)nc1C(=O)Cc1ccc(-c2cn(C)nc2NC(=O)OC(C)(C)C)cc1,,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20120202688A1,Oc1ccccc1.[N-]=[N+]=NC(=O)C1CC1c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1>>O=C(NC1CC1c1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1)Oc1ccccc1,,Cc1ccccc1,,CCN(CC)CC,CCOC(C)=O,test
US20130336920A1,NCc1cccc(C(F)(F)F)c1.O=C(O)c1ccnc(Cl)c1>>O=C(NCc1cccc(C(F)(F)F)c1)c1ccnc(Cl)c1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20110021498A1,CCOC(=O)c1cnn([C@@H](C)c2ccccc2)c1>>C[C@@H](c1ccccc1)n1cc(C(=O)O)cn1,,C1CCOC1,O,[Li+].[OH-],,test
US20100286126A1,CCC(=O)N(C(=O)OC(C)(C)C)[C@H]1C[C@@H](n2cnc3c(Cl)nc(Cl)nc32)[C@H](O)[C@@H]1O.NCC(c1ccc(O)cc1)c1ccc(O)cc1>>CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccc(O)cc4)c4ccc(O)cc4)nc(Cl)nc32)[C@H](O)[C@@H]1O.Cl,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US05686486,CC[Mg]Br.O=Cc1cccs1>>CCC(O)c1cccs1,,C1CCOC1,,,,test
US06008363,CN.COC(=N[N+](=O)[O-])NCc1ccc(Cl)nc1>>CNC(=N[N+](=O)[O-])NCc1ccc(Cl)nc1,,O,,,,test
US20080188521A1,COC(=O)c1ccc2c(-c3cccc(C)c3)cc(=O)oc2c1>>Cc1cccc(-c2cc(=O)oc3cc(C(=O)O)ccc23)c1,,C1CCOC1,Cl,[Li+].[OH-],,test
US20160152543A1,COc1cc2cccnc2cc1Cl.O=C1CCC(=O)N1I>>COc1c(Cl)cc2ncccc2c1I,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20100111900A1,COc1cc(Cn2c(=O)n(C)c3ccccc32)c(Br)cc1C(C)(C)C.OB(O)c1cccnc1OCc1ccccc1>>COc1cc(Cn2c(=O)n(C)c3ccccc32)c(-c2cccnc2OCc2ccccc2)cc1C(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,ClCCl,O=C([O-])[O-].[Na+].[Na+],,test
US20110269780A1,CCOC(=O)C[C@@H](Nc1nc(C)ccc1[N+](=O)[O-])c1ccccc1>>CCOC(=O)C[C@@H](Nc1nc(C)ccc1N)c1ccccc1,[Pd],CO,,,,test
US20150005304A1,CC(C)=O.COC(=O)c1cccnc1>>CC(=O)CC(=O)c1cccnc1,,C1CCOC1,,C[O-].[Na+],,test
US20080319188A1,C1CCOC1.CCN(CC)CC.Nc1cc(Oc2cc(F)c(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ccn1.O=C(Cl)Oc1ccccc1>>O=C(Nc1cc(Oc2cc(F)c(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ccn1)N1CC[C@H](O)C1,,C1CCOC1,CCOC(C)=O,O=C([O-])O.[Na+],,test
US20140206688A1,CSc1ccc2ncnc(Nc3cc(O)ccc3C)c2c1.O=S([O-])OO>>Cc1ccc(O)cc1Nc1ncnc2ccc(S(C)(=O)=O)cc12,,O,,CO,,test
US20080171786A1,CCC(C(=O)Nc1ccc(I)c(C(N)=O)c1)c1ccccc1.OB(O)c1ccc(-c2ccccc2)s1>>CCC(C(=O)Nc1ccc(-c2ccc(-c3ccccc3)s2)c(C(N)=O)c1)c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US20130200341A1,Brc1cccc(-c2c3ccc4ccccc4c3nc3c2ccc2ccccc23)c1.OB(O)c1ccc2ccc3cccc4ccc1c2c34>>c1cc(-c2c3ccc4ccccc4c3nc3c2ccc2ccccc23)cc(-c2ccc3ccc4cccc5ccc2c3c45)c1,,CCO,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20130296298A1,CCOC(=O)CSc1ccc2nnc(-c3cccs3)n2n1>>O=C(O)CSc1ccc2nnc(-c3cccs3)n2n1,,C1CCOC1,CO,[Na+].[OH-],,test
US04464531,CC(=O)OC[C@H]1O[C@@H](Oc2nc[nH]c2C(N)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>NC(=O)c1[nH]cnc1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O,,CO,,CC(=O)O,C[O-].[Na+],test
US04623652,CN(C)S(=O)(=O)NCCN.Cl.O=Cc1ccccc1>>CN(C)S(=O)(=O)NCCN=Cc1ccccc1.Cl,,c1ccccc1,,CCN(CC)CC,,test
US20130018030A1,CS(=O)(=O)N1CC=C(c2cc3c(cn2)O[C@H](C2CCNCC2)C3)CC1.FC(F)(F)c1cnc(Cl)nc1>>CS(=O)(=O)N1CC=C(c2cc3c(cn2)O[C@H](C2CCN(c4ncc(C(F)(F)F)cn4)CC2)C3)CC1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040053908A1,Nc1ccc(Oc2ncnc3[nH]c(-c4ccccc4)cc23)cc1.O=C=Nc1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)Nc1ccc(Oc2ncnc3[nH]c(-c4ccccc4)cc23)cc1,,CC#N,Cc1ccccc1,,,test
US04218448,Cc1c([N+](=O)[O-])c(=O)n2c3c(cc(C(O)(C(F)(F)F)C(F)(F)F)cc13)CC2>>Cc1c(N)c(=O)n2c3c(cc(C(O)(C(F)(F)F)C(F)(F)F)cc13)CC2,[Pd],,,,,test
US20040053908A1,C1CCNC1.N#Cc1cc2c(Oc3ccc(NC(=O)Nc4ccc(F)cc4)c(F)c3)ccnc2cc1OCC1CO1>>N#Cc1cc2c(Oc3ccc(NC(=O)Nc4ccc(F)cc4)c(F)c3)ccnc2cc1OCC(O)CN1CCCC1,,C1CCOC1,,,,test
US20060211678A1,CN(C)CCn1ccnc1-c1cccc([N+](=O)[O-])c1>>CN(C)CCn1ccnc1-c1cccc(N)c1,[Pd],CO,,,,test
US20100168136A1,Cc1cc(Br)ncc1C(S)c1c(F)ccc(F)c1F.FC(F)(F)CCI>>Cc1cc(Br)ncc1C(SCCC(F)(F)F)c1c(F)ccc(F)c1F,,O,,CN(C)C=O,[H-].[Na+],test
US20150284395A1,COC(=O)c1ccc(Cl)c(O)c1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>COC(=O)c1ccc(Cl)c(OCC(F)(F)F)c1,,CC(C)=O,,,,test
US20130261125A1,COC(=O)C1(Cc2ccccc2F)CCCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CCCC(CO)(Cc2ccccc2F)C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20060205731A1,CCOC(=O)C1CCNCC1.O=C(N=C=S)OCC1c2ccccc2-c2ccccc21>>CCOC(=O)C1CCN(C(N)=S)CC1,,ClC(Cl)Cl,,CCOCC,,test
US20080255086A1,CS(=O)(=O)Cl.NC(=O)c1c(NC(=O)Cn2cc(CCO)c(C(F)(F)F)n2)sc2c1CCCC2>>CS(=O)(=O)OCCc1cn(CC(=O)Nc2sc3c(c2C(N)=O)CCCC3)nc1C(F)(F)F,,ClCCl,,CCN(CC)CC,O,test
US20090069370A1,COc1ccc2c(c1)CCN([C@@H]1CCN(Cc3ccccc3)C1)C2=O>>O=C1c2ccc(O)cc2CCN1[C@@H]1CCN(Cc2ccccc2)C1,,CO,,,,test
US05290477,CCCC[C@@H](F)CCOc1cnc(-c2ccc(OCc3ccccc3)cc2)nc1>>CCCC[C@@H](F)CCOc1cnc(-c2ccc(O)cc2)nc1,,C1CCOC1,,CO,[H][H],test
US20050282823A1,C1COC2(CC3CNCC2C3)O1.CCOC(=O)Cl>>CCOC1(N2CC3CC(=O)C(C3)C2)OCCO1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20040023974A1,CC(C)(C)O.COC(=O)Cc1ccccc1NCC(=O)OC(C)(C)C.O=C=NS(=O)(=O)Cl>>COC(=O)Cc1ccccc1N(CC(=O)OC(C)(C)C)S(=O)(=O)NC(=O)OC(C)(C)C,,ClCCl,,O,,test
US20040002524A1,CCOC(=O)C(F)(F)F.COc1ccc(C(Cc2ccccc2)=NO)cc1>>COc1ccc(C2=NOC(O)(C(F)(F)F)C2c2ccccc2)cc1,,C1CCOC1,,[Li]CCCC,,test
US20080086003A1,CCc1ccc(C[C@@H](NC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCN(C3CCN(C)CC3)CC2)cc1CC.O=S(=O)(O)c1cccc2c(S(=O)(=O)O)cccc12>>CCc1ccc(C[C@@H](NC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCN(C3CCN(C)CC3)CC2)cc1CC.O=S(=O)([O-])c1cccc2c(S(=O)(=O)[O-])cccc12,,CC(C)O,,,,test
US20110092512A1,O=C1NCCC12CCC1(CC2)OCCO1.OC(c1ccc(I)cc1)C(F)(F)F>>O=C1N(c2ccc(C(O)C(F)(F)F)cc2)CCC12CCC1(CC2)OCCO1,,CN(C)C=O,,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20070197512A1,CCc1cccc2c1OC(C(C)C)C(=O)N2CCC(=O)OC>>CCc1cccc2c1OC(C(C)C)C(=O)N2CCC(=O)O,,CO,,[Na+].[OH-],,test
US20060084673A1,Cc1ccc(CBr)c(C)c1.NC1=NC(=O)CN1C(=O)OCc1ccccc1>>Cc1ccc(CNC2=NC(=O)CN2C(=O)OCc2ccccc2)c(C)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060004017A1,COc1cc2c(Oc3ccccc3)ncnc2cc1O.ClCCN1CCCCC1>>COc1cc2c(Oc3ccccc3)ncnc2cc1OCCN1CCCCC1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20110070317A1,CC(C)(C)OC(=O)N[C@@H]1CCCNC1.CO[C@H](C)C(=O)Nc1c[nH]c2ncc(F)c(F)c12.ClCCl>>CO[C@H](C)C(=O)Nc1c[nH]c2ncc(F)c(N3CCC[C@@H](N)C3)c12.Cl,,CCCCO,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20060264440A1,Brc1cccc(-c2n[nH]cc2-c2ccc3c(c2)OCO3)n1.CN(C)S(=O)(=O)Cl>>CN(C)S(=O)(=O)n1cc(-c2ccc3c(c2)OCO3)c(-c2cccc(Br)n2)n1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20160152561A1,Nc1cccc(S(N)(=O)=O)c1.O=C(Cl)c1c(F)cc(C(F)(F)F)cc1C(F)(F)F>>NS(=O)(=O)c1cccc(NC(=O)c2c(F)cc(C(F)(F)F)cc2C(F)(F)F)c1,,COC(C)(C)C,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20100197681A1,CC(C)N.Nc1nc2cc(C(F)(F)F)cc(Cl)n2n1>>CC(C)Nc1cc(C(F)(F)F)cc2nc(N)nn12,,CCCCO,,,,test
US20130116243A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)NC(=O)CO4)cc2)CCC1.CCOC(=O)CBr>>CCOC(=O)CN1C(=O)COc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20140315888A1,CCOC(=O)C(=O)OCC.Nc1cc(Cl)c(Cl)nc1N>>O=c1[nH]c2cc(Cl)c(Cl)nc2[nH]c1=O,,CCOCC,,,,test
US20060166997A1,COC(=O)C1CCN(C(=O)OC(C)(C)C)C1c1cc([N+](=O)[O-])ccc1S(=O)(=O)C(C)C>>COC(=O)C1CCN(C(=O)OC(C)(C)C)C1c1cc(N)ccc1S(=O)(=O)C(C)C,[Pd],CO,,,,test
US04931581,CI.O=C(O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1Cl.SCc1ccccc1>>COC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1SCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070276011A1,O=C1CSC(=O)N1Cc1ccc(Cl)c(Cl)c1.O=Cc1cc(C=Cc2ccccc2)ccc1O>>O=C1SC(=Cc2cc(C=Cc3ccccc3)ccc2O)C(=O)N1Cc1ccc(Cl)c(Cl)c1,,CCO,,C,O=C[O-].[NH4+],test
US04478835,C1COCCO1.CC(C)c1ncc2cc(Cl)nc(Cl)n12.CCCN.ClC(Cl)Cl>>CCCNc1nc(Cl)cc2cnc(C(C)C)n12.Cl.O,,ClC(Cl)Cl,,,,test
US06166064,Brc1cccc(Br)c1.O=C1CCC1>>OC1(c2cccc(Br)c2)CCC1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20080167287A1,CC(C)(C)OC(=O)N1CCN(c2ccc(-c3cnc(N)nc3)cn2)CC1.O=CC(Cl)C1(c2ccc3ncccc3c2)CC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(-c3cnc4ncc(C5(c6ccc7ncccc7c6)CC5)n4c3)cn2)CC1,,CC(C)O,CO,,,test
US20110105462A1,O=C(OO)c1cccc(Cl)c1.O=Cc1cc(F)ccc1OCC1CO1>>Oc1cc(F)ccc1OCC1CO1,,ClCCl,,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US20150266867A1,CC(C)(C)OC(=O)Nc1nc(/C(=N/OC2(C(=O)OC(c3ccccc3)c3ccccc3)CC2)C(=O)N[C@@H]2C(=O)N(S(=O)(=O)O)[C@@H]2Cn2ncc(CN(CC3CN(C(=O)OC(C)(C)C)C3)C(=O)OC(C)(C)C)n2)cs1>>Nc1nc(/C(=N/OC2(C(=O)O)CC2)C(=O)N[C@@H]2C(=O)N(S(=O)(=O)O)[C@@H]2Cn2ncc(CNCC3CNC3)n2)cs1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150119405A1,CC(C)(C)[Si](C)(C)O[C@H]1[C@H]2C[C@H]2C[C@@H]1C(=O)O.OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](C)(C)O[C@H]1[C@H]2C[C@H]2C[C@@H]1NC(=O)OCc1ccccc1,,CCOC(C)=O,Cc1ccccc1,CCN(CC)CC,,test
US20020115859A1,CC1(C)CN(CCOCCC#N)C(=O)C(C)(C)N1>>CC1(C)CN(CCOCCCN)C(=O)C(C)(C)N1,[Ni],CO,,,,test
US20110118245A1,COC(=O)c1cc(OCc2ccccc2)c(OC)cc1[N+](=O)[O-]>>COC(=O)c1cc(OCc2ccccc2)c(OC)cc1N,,CO,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20160009704A1,CC(C)(C)OC(=O)c1cn(CCC(F)Cn2cc(NC(=O)Cc3ccccn3)nn2)nn1>>O=C(Cc1ccccn1)Nc1cn(CC(F)CCn2cc(C(=O)O)nn2)nn1,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20020082254A1,CC(C)(C)OC(=O)Nc1ccc(O)cc1.NN1CCc2ccccc2C1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)Nc1ccc(OC(=O)NN2CCc3ccccc3C2)cc1,,CCN(CC)CC,ClCCl,Cl,c1ccncc1,test
US20020107273A1,CCc1nc2cc(NS(C)(=O)=O)c(Cl)cc2n1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1.O=CO>>CCc1nc2cc(NC)c(Cl)cc2n1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1,,C1CCOC1,,CC(=O)OC(C)=O,,test
US20050184287A1,O=C(O)CC(=O)O.O=Cc1ccc(N(c2ccccc2)c2ccccc2)cc1>>O=C(O)C=Cc1ccc(N(c2ccccc2)c2ccccc2)cc1,,c1ccncc1,,C1CCNCC1,Cl,test
US20100010053A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCC(=O)O)c[nH]c34)no2)cc1Cl.CCCCI.CCOC(C)=O.CS(C)=O>>CCCCOC(=O)CCc1cn(CCCC)c2c(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)cccc12,,CCOC(C)=O,CS(C)=O,[K+].[OH-],,test
US08318757B2,CC(c1ccc(C2=NOC(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1)N1C(=O)c2ccccc2C1=O>>CC(N)c1ccc(C2=NOC(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1,,CCO,,NN,O,test
US06124283,CN1CCN(c2cccc3c2C[C@H](N)CC3)CC1.CS(=O)(=O)Oc1ccc(C(=O)O)cc1>>CN1CCN(c2cccc3c2C[C@H](NC(=O)c2ccc(OS(C)(=O)=O)cc2)CC3)CC1,,ClCCl,O=S(Cl)Cl,CCN(CC)CC,,test
US20100048949A1,c1ccc([C@@H]2[C@H](c3ccccc3)N2c2ccccc2)cc1>>c1ccc(CC(Nc2ccccc2)c2ccccc2)cc1,,Cc1ccccc1,,N#N,,test
US20110160256A1,COC(=O)c1nc(-c2c(Cl)cnn2C)cs1>>Cn1ncc(Cl)c1-c1csc(C(=O)O)n1,,C1CCOC1,O,[K+].[OH-],,test
US20070167423A1,CC(=O)Cc1cccc(Br)c1.Cc1ccc2c(N3CCN(CCc4cccc(N)c4)CC3)cccc2n1>>Cc1ccc2c(N3CCN(CC(C)c4cccc(Br)c4)CC3)cccc2n1,,CO,,[BH3-]C#N.[Na+],,test
US05783704,CCOCC(=O)CCl.COc1n[nH]c(=O)s1>>CCOC(C(C)=O)n1nc(OC)sc1=O,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20030036557A1,CS(=O)(=O)c1ccc(NC(=N)c2ccc(F)cc2)cc1.O=C(CBr)C(F)(F)F>>CS(=O)(=O)c1ccc(N2CC(O)(C(F)(F)F)N=C2c2ccc(F)cc2)cc1,,CC(C)O,,O=C([O-])O.[Na+],,test
US20100240620A1,C/C(N)=C/C#N.CC(=O)Cc1nc(C)cs1.COc1cc(C#N)ccc1C=O>>COc1cc(C#N)ccc1C1C(C#N)=C(C)NC(C)=C1c1nc(C)cs1,,CC(C)O,,,,test
US20120010191A1,CI.COC(=O)c1cc([N+](=O)[O-])[nH]n1>>COC(=O)c1cc([N+](=O)[O-])nn1C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080255183A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(CCCc2ccc3c(n2)NCCC3)s1)C(=O)[O-].ClCCl>>COC(=O)[C@@H](N)Cc1ccc(CCCc2ccc3c(n2)NCCC3)s1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04906634,CCN(CC)CCOc1ccc(N)cc1.CS(=O)(=O)OS(C)(=O)=O>>CCN(CC)CCOc1ccc(NS(C)(=O)=O)cc1.CS(=O)(=O)O,,CC#N,,,,test
US20040142850A1,CCOC(=O)Nc1ccc(Cl)cc1Cl.O=[N+]([O-])c1cc([N+](=O)[O-])c(Cl)c(C(F)(F)F)c1>>CCOC(=O)N(c1ccc(Cl)cc1Cl)c1c([N+](=O)[O-])cc([N+](=O)[O-])cc1C(F)(F)F,,C1CCOC1,,Cl,[H-].[Na+],test
US20130237555A1,Nc1nccc(-c2ccc(Cl)cc2F)c1C=O>>Nc1nccc(-c2ccc(Cl)cc2F)c1CO,,C1CCOC1,CO,[BH4-].[Na+],,test
US20160159815A1,COc1nc(C(=O)N2CC[C@]3(c4cccc(F)c4)OCO[C@@H]3C2)ccc1O.CS(=O)(=O)OCC1CC2(C1)CC(F)(F)C2>>COc1nc(C(=O)N2CC[C@]3(c4cccc(F)c4)OCO[C@@H]3C2)ccc1OCC1CC2(C1)CC(F)(F)C2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160168122A1,Cn1cc(N)cn1.Nc1nc(Cl)nc(Cl)n1>>Cn1cc(Nc2nc(N)nc(Cl)n2)cn1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US05089043,COC(=O)C(C)Oc1ccc(Oc2cnc3cc(Cl)ccc3n2)cc1>>CC(Oc1ccc(Oc2cnc3cc(Cl)ccc3n2)cc1)C(=O)O,,C1CCOC1,,CO,[Na+].[OH-],test
US20060128700A1,CC(=O)O/C=C(\C#N)N1C2CCCC1COC2.N=C(N)c1nn(Cc2ccccc2F)c2ccccc12>>Nc1nc(-c2nn(Cc3ccccc3F)c3ccccc23)ncc1N1C2CCCC1COC2,,Cc1ccccc1,,,,test
US20030078251A1,COC(=O)[C@H](CCSC)NC(=O)C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2N(CC(C)(C)CO)C1=O>>COc1cccc([C@H]2O[C@H](CC(=O)N[C@@H](CCSC)C(=O)O)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC,,C1CCOC1,CO,O,[Na+].[OH-],test
US20030114442A1,CC(=O)Cl.Nc1ccc(CC(=O)N2CCN(CCCCC3(C(=O)NCC(F)(F)F)c4ccccc4-c4ccccc43)CC2)cc1>>CC(=O)Nc1ccc(CC(=O)N2CCN(CCCCC3(C(=O)NCC(F)(F)F)c4ccccc4-c4ccccc43)CC2)cc1,,ClCCl,,,,test
US20050014765A1,CCOC(=O)c1cc[nH]c1-c1ccccc1>>O=C(O)c1cc[nH]c1-c1ccccc1,,CCO,,[Na+].[OH-],,test
US20110183997A1,Cc1cc2c(cn1)cc(-c1cc(N=C=S)ccc1C)c(=O)n2C.NNC(=O)c1ccccc1>>Cc1cc2c(cn1)cc(-c1cc(NC(=S)NNC(=O)c3ccccc3)ccc1C)c(=O)n2C,,CCO,,,,test
US05476851,COc1ccc(C(C)=O)cc1F.O=[Se]>>COc1ccc(C(=O)C=O)cc1F,,C1COCCO1,,,,test
US04584318,CC(=O)OC(C)=O.CCCON=Cc1cc(Cl)ccc1O>>CCCON=Cc1cc(Cl)ccc1OC(C)=O,,CC(=O)OC(C)=O,,CC(=O)[O-].[Na+],,test
US20010039343A1,CCSC(=O)OC(I)C(=O)OC(C)C.O=C(O)c1ccccc1>>CCSC(=O)OC(OC(=O)c1ccccc1)C(=O)OC(C)C,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US05182283,CCCCSc1nccnc1C1(O)CN2CCC1CC2.O=S(Cl)Cl>>CCCCSc1nccnc1C1(Cl)CN2CCC1CC2,,ClCCl,,,,test
US20140303139A1,COC(=O)c1cc(N(CC2COC(C)(C)O2)S(C)(=O)=O)nc(Cl)n1.N>>CC1(C)OCC(CN(c2cc(C(N)=O)nc(Cl)n2)S(C)(=O)=O)O1,,CO,,,,test
US06013658,CN(C(=O)OC(C)(C)C)[C@H](Cc1ccccc1)c1nnc(C(N)=O)o1>>CN[C@H](Cc1ccccc1)c1nnc(C(N)=O)o1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05180833,ClCc1cnc(Cl)s1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1Cc1cnc(Cl)s1,,CN(C)C=O,,[K],,test
US04377580,CC1(C)OC(=O)C(=CNc2ncnc3ccccc23)C(=O)O1>>O=c1ccnc2c3ccccc3ncn12,,c1ccc(Oc2ccccc2)cc1,,CCCCCC,CCOC(C)=O,test
US03957777,CCCCCCCCNC.O=C(c1ccccc1)c1ccc(Cl)c([N+](=O)[O-])c1>>CCCCCCCCN(C)c1ccc(C(=O)c2ccccc2)cc1[N+](=O)[O-],,CCO,,,,test
US20110124634A1,CCOC(=O)c1nc(NC(=O)C(C)C)cn1COC>>COCn1cc(NC(=O)C(C)C)nc1C=O,O=[Mn]=O,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140024649A1,CC(C)(C)OC(=O)N1OC2C=CC1C2>>CC(C)(C)OC(=O)N[C@H]1CC[C@@H](O)C1,[Pd],CO,,,,test
US20030158219A1,COC(=O)CBr.O=C1Nc2ccccc2CC1CN1CCC2(CCc3ccccc32)CC1>>COC(=O)CN1C(=O)C(CN2CCC3(CCc4ccccc43)CC2)Cc2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20160137595A1,COc1ccc(-c2ccc(Oc3ccccc3C(C)(C)C)c(N)c2)cc1[N+](=O)[O-].Cc1ccc(N=C=O)cc1>>Cc1ccc(NC(N)=O)cc1,,C1CCOC1,,,,test
US20020188127A1,CC(C)(C)Nc1c([N+](=O)[O-])c2nnnn2c2ccccc12>>CC(C)(C)Nc1c(N)c2nnnn2c2ccccc12,[Pt],CCO,,,,test
US20050267095A1,CN(C)C=NC(=O)C1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1.NN>>c1nc(C2(c3ccc(OCCCN4CCCC4)cc3)CCOCC2)n[nH]1,,CC(=O)O,,O,,test
US05625080,CCOC(=O)C(O)(C(=O)OCC)c1cc(C)ccc1C>>Cc1ccc(C)c(C(O)C(=O)O)c1,,O,,[K+].[OH-],,test
US20130281438A1,NC1CCC1.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=[N+]([O-])c1ccccc1S(=O)(=O)NC1CCC1,,ClCCl,,CCN(CC)CC,,test
US20100184815A1,CCCNC(=O)NNC(=O)[C@H](C)OCc1ccccc1>>CCCn1c([C@H](C)OCc2ccccc2)n[nH]c1=O,,CCO,,[K+].[OH-],,test
US20130035325A1,CC(C)(CO)NC(=O)CC#N.Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)cn2-c1cccc(C=O)c1>>CC(C)(CO)NC(=O)/C(C#N)=C/c1cccc(-n2cc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)c1,,CC(C)O,,C1CC[NH2+]CC1.CC(=O)[O-],,test
US20100056490A1,COC[C@@H](Oc1cc(C[C@@H]2C[S@](=O)C[C@H](NCc3cccc(C(C)(C)C)c3)[C@H]2O)cc(F)c1[N+](=O)[O-])C(F)(F)F>>COC[C@@H](Oc1cc(C[C@@H]2C[S@](=O)C[C@H](NCc3cccc(C(C)(C)C)c3)[C@H]2O)cc(F)c1N)C(F)(F)F,,CCOC(C)=O,CO,,,test
US20110263629A1,C=CCN=C=O.CC(C)(C)OC(=O)N1C[C@H]2CNC[C@@H]1C2>>C=CCNC(=O)N1C[C@@H]2C[C@@H](CN2)C1,,ClCCl,,CCN(CC)CC,,test
US20060281810A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(Cl)c(F)cc1Br>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1cc(Cl)c(F)cc1Br,CN(C)c1ccncc1,C1CCOC1,CCOC(C)=O,,,test
US05527827,NC=S.O=C(CBr)c1cc(=O)oc2cc(Br)ccc12>>O=c1cc(-c2cscn2)c2ccc(Br)cc2o1,,C1CCOC1,,CCOC(C)=O,,test
US20100311693A1,ClCc1ccc(Br)cc1.O=S1(=O)CCNCC1>>O=S1(=O)CCN(Cc2ccc(Br)cc2)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160002225A1,COc1ccc(Oc2ccccc2)cc1S(=O)(=O)O.O=P(Cl)(Cl)Cl>>COc1ccc(Oc2ccccc2)cc1S(=O)(=O)Cl,,O=P(Cl)(Cl)Cl,,ClP(Cl)(Cl)(Cl)Cl,,test
US20100267750A1,Cn1c(=O)c2c(ncn2CC(=O)O)n(C)c1=O.N#Cc1ccc(CCN)cc1>>Cn1c(=O)c2c(ncn2CC(=O)NCCc2ccc(C#N)cc2)n(C)c1=O,,CCOC(C)=O,,,,test
US20080045544A1,CC(C)(C)OC(=O)Oc1ccc(N(C(=O)OC(C)(C)C)C2CCN(C(=O)OC(C)(C)C)CC2)nc1>>CC(C)(C)OC(=O)N1CCC(N(C(=O)OC(C)(C)C)c2ccc(O)cn2)CC1,,C1CCOC1,CO,O,[Li+].[OH-],test
US03935217,CCOC(=O)C1C(=O)NCC1c1ccc2c(c1)OCO2.COc1ccc(CCl)cc1OC>>CCOC(=O)C1(Cc2ccc(OC)c(OC)c2)C(=O)NCC1c1ccc2c(c1)OCO2,,CCO,,[Na],,test
US20080312216A1,COC(=O)C(C)c1ccc(Cl)c(Cl)c1.COC(CBr)OC>>COC(=O)C(C)(CC(OC)OC)c1ccc(Cl)c(Cl)c1,,CN(C)C=O,,[H-].[Na+],,test
US20010053823A1,C=Cc1nc(C#N)c(C#N)[nH]1.COS(=O)(=O)OC>>C=Cc1nc(C#N)c(C#N)n1C,,C1CCOC1,CCOCC,,,test
US20100216814A1,C#Cn1c2c(c3cc(Cl)ccc31)CN(C)CC2.FC(F)(F)c1ccc(Br)cn1>>CN1CCc2c(c3cc(Cl)ccc3n2C#Cc2ccc(C(F)(F)F)nc2)C1,,CC#N,O,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04985419,CC(C)=O.CC(CN1CCCC1)N1c2ccccc2Sc2ccc(C#N)cc21.Cl.[OH-]>>CC(CN1CCCC1)N1c2ccccc2Sc2ccc(C(=O)O)cc21.Cl,,CCOCC,,Cl,,test
US20130096113A1,CS(=O)c1nc2ccc(Cn3cnc4cc(I)ccc43)cc2s1.N[C@@H]1CCC[C@@H](O)[C@H]1O>>O[C@@H]1CCC[C@@H](Nc2nc3ccc(Cn4cnc5cc(I)ccc54)cc3s2)[C@@H]1O,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,Cl,test
US20150274696A1,O=[N+]([O-])c1ccc2ncoc2c1>>Nc1ccc2ncoc2c1,[Pd],Cc1ccccc1,,N#N,,test
US04299831,Nc1nccs1.O=C(Cl)c1c(C(F)(F)F)nc2ccccc2c1O>>O=C(Nc1nccs1)c1c(C(F)(F)F)nc2ccccc2c1O,,c1ccncc1,,,,test
US20070049596A1,C=CC[Mg]Cl.O=[N+]([O-])/C=C/c1cc(F)c(F)cc1F>>C=CCC(C[N+](=O)[O-])c1cc(F)c(F)cc1F,,C1CCOC1,,,,test
US05622976,O=[N+]([O-])c1ccc(-c2nc(C(O)CCCC3CCN(Cc4ccccc4)CC3)no2)cc1>>O=C(CCCC1CCN(Cc2ccccc2)CC1)c1noc(-c2ccc([N+](=O)[O-])cc2)n1,,CS(C)=O,,O=P(O)(O)O,,test
US20070135477A1,Nc1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1.O=C(O)c1onc2ccccc12>>O=C(Nc1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1)c1onc2ccccc12,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20130085129A1,CC(C)(C)OC(=O)N1CCN(C(=O)C(F)(F)F)CC1>>O=C(N1CCNCC1)C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140093505A1,CC(C)(C)OC(=O)N1CCN(c2ccc(-n3c(=O)ccc4cnc5ccc(-c6ccc(N)nc6)nc5c43)cc2C(F)(F)F)CC1.Cl>>Cl.Nc1ccc(-c2ccc3ncc4ccc(=O)n(-c5ccc(N6CCNCC6)c(C(F)(F)F)c5)c4c3n2)cn1,,ClCCl,,,,test
US06376530B1,C=CCNC(=O)c1ccc(OC(F)(F)F)cc1>>CC=CNC(=O)c1ccc(OC(F)(F)F)cc1,,C1CCOC1,,CC(C)NC(C)C,,test
US20150284395A1,CC(=O)N(C)C.CCn1ncc2cc(-c3cc(=O)n4nc(C)c(C(N)=O)c4[nH]3)ccc21>>CCn1ncc2cc(-c3cc(=O)n4nc(C)c(C(=O)/N=C(\C)N(C)C)c4[nH]3)ccc21,,CN(C)C=O,,CC(=O)N(C)C,,test
US20030013875A1,C=CCN1CC2C(C1=O)C2(C)c1cccc(N)c1>>C=CCN1CC2C(C1)C2(C)c1cccc(N)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070287701A1,COc1ccc2ncc(Cl)c(CCN3CC[C@@H](CNC(=O)OCc4ccccc4)C3)c2n1>>COc1ccc2ncc(Cl)c(CCN3CC[C@@H](CN)C3)c2n1,,CO,,O,[K+].[OH-],test
US20080027090A1,CCCCC(=O)Cl.Nc1cc2c3c(c1)c1c(n3CCC2)CCCCC1>>CCCCC(=O)Nc1cc2c3c(c1)c1c(n3CCC2)CCCCC1,,CC(Cl)Cl,,,,test
US20110190489A1,CC(C)[Si](Cl)(C(C)C)C(C)C.Clc1ccnc2[nH]cc(I)c12>>CC(C)[Si](C(C)C)(C(C)C)n1cc(I)c2c(Cl)ccnc21,,CN(C)C=O,,[H-].[Na+],,test
US04956359,Clc1ccc(SC2CN(C(c3ccccc3)c3ccccc3)C2)cc1.O=C(Cl)Cl>>O=C(Cl)N1CC(Sc2ccc(Cl)cc2)C1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20090099204A1,O=C(Nc1c(Br)cc(C(O)(C(F)(F)F)C(F)(F)F)cc1SC(F)(F)F)c1cccc(NC(=O)c2ccccc2F)c1.O=S(Cl)Cl>>O=C(Nc1c(Br)cc(C(Cl)(C(F)(F)F)C(F)(F)F)cc1SC(F)(F)F)c1cccc(NC(=O)c2ccccc2F)c1,,c1ccncc1,,,,test
US20120245152A1,C[C@@H](O)C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1.Oc1cc(Cl)cnc1Cl>>C[C@H](Oc1cc(Cl)cnc1Cl)C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,O,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150183802A1,CC(C)=NOc1cc2c(-c3cnc(OCC(C)C)c(Cl)c3)nn(C)c2cc1C#N.O=S(=O)(Cl)C1CC1>>CC(C)COc1ncc(-c2nn(C)c3cc4c(NS(=O)(=O)C5CC5)noc4cc23)cc1Cl,CN(C)c1ccncc1,ClCCl,c1ccncc1,,,test
US20100286390A1,CON(C)C(=O)c1cn[nH]c1.C[Si](C)(C)CCOCCl>>CON(C)C(=O)c1cnn(COCC[Si](C)(C)C)c1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,ClCCl,test
US20060025465A1,CCC1(c2cnc(S)n2Cc2ccccc2)Cc2ccc(F)cc2C1>>CCC1(c2cncn2Cc2ccccc2)Cc2ccc(F)cc2C1,[Ni],CCO,,,,test
US20090325937A1,NC(=O)c1cccc(NC(=O)c2cc(Cl)nnc2Cl)c1N>>NC(=O)c1cccc2c1Nc1nnc(Cl)cc1C(=O)N2,,CC(=O)O,,,,test
US20110306636A1,CCC1CCCCN1c1ccc(Br)cc1COC.Cl.O=C=O>>CCC1CCCCN1c1ccc(C(=O)O)cc1COC.Cl,,C1CCOC1,,[Li]CCCC,,test
US20130102782A1,CCC(C)(N)C(=O)OC.Clc1ccnc(Cl)n1>>CCC(C)(Nc1ccnc(Cl)n1)C(=O)OC,,O,,CN1CCCC1=O,,test
US20150239837A1,CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)O.O=C(CBr)c1cccc(Cl)c1>>CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)OCC(=O)c1cccc(Cl)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20160194316A1,CCN(c1cc(Cl)cc(C(=O)NCc2c(OC)nn(C)c2N2CCCCC2)c1C)[C@@H]1CC[C@@H](N(C)Cc2cccc(OC)c2)CC1>>CCN(c1cc(Cl)cc(C(=O)NCc2c(O)nn(C)c2N2CCCCC2)c1C)[C@@H]1CC[C@@H](N(C)Cc2cccc(OC)c2)CC1,,Cl,,,,test
US20160130299A1,CCCN(C(=O)[C@@H](N=[N+]=[N-])[C@@H](C)CC)[C@H](C[C@@H](OC(=O)NC)c1nc(C(=O)OC)cs1)C(C)C>>CCCN(C(=O)[C@@H](N=[N+]=[N-])[C@@H](C)CC)[C@H](C[C@@H](OC(=O)NC)c1nc(C(=O)O)cs1)C(C)C,,C1CCOC1,CO,[Li+].[OH-],,test
US08759520B2,BrCc1ccc(Br)cc1.N=c1[nH]c2ccccc2n1CCCOc1ccc(F)cc1>>N=c1n(CCCOc2ccc(F)cc2)c2ccccc2n1Cc1ccc(Br)cc1,,CCC(C)=O,,,,test
US20050234031A1,CN1C(=O)C=CC1=O.COCN(Cc1ccccc1)C[Si](C)(C)C>>CN1C(=O)C2CN(Cc3ccccc3)CC2C1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US06420409B1,CS(=O)(=O)Cl.OCc1ccc(C(F)(F)F)cc1Cl>>CS(=O)(=O)OCc1ccc(C(F)(F)F)cc1Cl,,ClCCl,,CCN(CC)CC,,test
US20100120761A1,Nc1cccc(N)c1.O=[N+]([O-])c1cc(Br)cnc1Cl>>Nc1cccc(Nc2ncc(Br)cc2[N+](=O)[O-])c1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US06610692B1,CC(C)(C)OC(=O)CBr.CCOC(=O)c1cc(C)[nH]c(=O)c1OCc1ccccc1>>CCOC(=O)c1cc(C)n(CC(=O)OC(C)(C)C)c(=O)c1OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040142941A1,COc1ccc(-c2nn3c(NC4CCCC4)cc(Cl)cc3c2-c2ccnc(SC)n2)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(-c2nn3c(NC4CCCC4)cc(Cl)cc3c2-c2ccnc(S(C)=O)n2)cc1,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US05750523,COc1ccc(CN)cc1OC.O=c1[nH]nc(OCCC(O)c2ccc(Cl)cc2)c(Br)c1Br>>COc1ccc(CNc2c(OCCC(O)c3ccc(Cl)cc3)n[nH]c(=O)c2Br)cc1OC,,CCN(CC)CC,,,,test
US20120053188A1,COC(=O)CCCCCCc1nc2ccc(-c3ccccc3)cc2[nH]1.NO>>O=C(CCCCCCc1nc2ccc(-c3ccccc3)cc2[nH]1)NO,,C1CCOC1,,[K+].[OH-],,test
US20080027126A1,C=C[Mg]Br.CON(C)C(=O)C1CCCCC1>>C=CC(=O)C1CCCCC1,,C1CCOC1,,[Cl-].[NH4+],,test
US20030134859A1,CCOC(=O)c1ccc(NC(=O)c2cc([N+](=O)[O-])ccc2Cl)cc1>>O=C(O)c1ccc(NC(=O)c2cc([N+](=O)[O-])ccc2Cl)cc1,,C1COCCO1,,[Na+].[OH-],,test
US20090062282A1,CCOC(=O)/C=C(\C)c1ccc(Cl)c(Cl)c1.N=C(N)N>>CC1(c2ccc(Cl)c(Cl)c2)CC(=O)NC(N)=N1,,CN1CCCC1=O,,Cl,C[O-].[Na+],test
US04686220,O=C1c2ccccc2C(=O)C2OC12.c1ccc2oc(N3CCNCC3)nc2c1>>O=C1C(O)=C(N2CCN(c3nc4ccccc4o3)CC2)C(=O)c2ccccc21,,CCO,,,,test
US20130274479A1,O=C(Cl)c1ccc(Cl)cc1.O=C(NO)OCC1c2ccccc2-c2ccccc21>>O=C(NOC(=O)c1ccc(Cl)cc1)OCC1c2ccccc2-c2ccccc21,,CCOC(C)=O,,CCN(CC)CC,O,test
US20090192213A1,COC(=O)c1cc(C)ccc1S.O=C1CCC(=O)N1Cl>>COC(=O)c1cc(C)ccc1SCl,,ClCCCl,,,,test
US20150111891A1,Cc1cc2ccc(Br)cc2c(O)c1[C@@H](COC(=O)C(C)(C)C)OC(C)(C)C.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1cc2ccc(Br)cc2c(OS(=O)(=O)C(F)(F)F)c1[C@@H](COC(=O)C(C)(C)C)OC(C)(C)C,,ClCCl,,CCN(C(C)C)C(C)C,[Cl-].[NH4+],test
US20090042874A1,CC(C)(C)OC(=O)N1CC[C@H](OS(=O)(=O)c2ccccc2[N+](=O)[O-])C1.O=C1COc2ccc(O)cc2N1>>CC(C)(C)OC(=O)N1CC[C@@H](Oc2ccc3c(c2)NC(=O)CO3)C1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070232590A1,Ic1ccc(I)nn1.Oc1ccc2c(c1)CCN(C1CCCC1)CC2>>Ic1ccc(Oc2ccc3c(c2)CCN(C2CCCC2)CC3)nn1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150175619A1,CC(C)n1nc(I)cc1[C@@H]1[C@H]2C=CC[C@H]21.C[N+](C)(C)[O-]>>CC(C)n1nc(I)cc1[C@H]1[C@@H]2CC3CN(C)C[C@H]3[C@H]12,,C1CCOC1,O,CC(C)[N-]C(C)C.[Li+],,test
US20080096877A1,CN(c1cccc2cc(C3=NCC(CC=O)S3)[nH]c12)S(=O)(=O)c1cccs1.Nc1nnc[nH]1>>CN(c1cccc2cc(C3=NCC(CCNc4nnc[nH]4)S3)[nH]c12)S(=O)(=O)c1cccs1,,CC(=O)O,,O=C([O-])O.[Na+],,test
US20070208036A1,N#CBr.Nc1ccccc1CNC1CCN(Cc2ccccc2)CC1>>NC1=Nc2ccccc2CN1C1CCN(Cc2ccccc2)CC1,,CCO,,ClCCl,[Na+].[OH-],test
US20130102585A1,COC(=O)c1ccc2c(c1)CCN2Cc1ccccc1>>O=C(O)c1ccc2c(c1)CCN2Cc1ccccc1,,C1CCOC1,O,[Li]O,,test
US20080039440A1,CCOC(=O)c1cc(Oc2ccc3[nH]ccc3c2)ncn1>>CCOC(=O)c1cc(Oc2ccc3c(c2)CCN3)ncn1,,CC(=O)O,,O,[BH3-]C#N.[Na+],test
US20100152190A1,CC(C)(C)[Si](C)(C)Cl.CC1(C)OC(=O)[C@H](CCO)O1>>CC1(C)OC(=O)[C@H](CCO[Si](C)(C)C(C)(C)C)O1,,CN(C)C=O,,O,c1c[nH]cn1,test
US20030008768A1,Cc1ccccc1B(O)O.O=Cc1ccc(Cl)cc1>>Cc1ccccc1-c1ccc(C=O)cc1,,C1CCOC1,,[F-].[K+],,test
US04409234,BrCCCBr.Cc1ccc2[nH]nc(-c3ccccc3)c2c1>>Cc1ccc2c(c1)c(-c1ccccc1)n1[n+]2CCC1.[Br-],,CN(C)C=O,,[H-].[Na+],,test
US20140235671A1,BrCc1ccccc1.Oc1ccnc(Br)c1>>Brc1cc(OCc2ccccc2)ccn1,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20060019985A1,CC(C)(C)OC(=O)N1CCC(C(=O)NCC2CCN(C(=O)OC(C)(C)C)C2)CC1>>O=C(NCC1CCNC1)C1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05753709,CCCC(=O)NC[C@@H]1C[C@H]1c1cccc(O)c1.CCCC(N)=O.ClCCl>>C=CCOc1cccc([C@@H]2C[C@H]2CNC(=O)CCC)c1,,ClCCl,,BrB(Br)Br,,test
US20120259123A1,CC(C)(C)OC(=O)CN(C(=O)OC(C)(C)C)c1cccc(C(Cc2ccc(C(C)(C)C)cc2)NS(=O)(=O)c2cccc(F)c2)n1.Cl>>CC(C)(C)c1ccc(CC(NS(=O)(=O)c2cccc(F)c2)c2cccc(NCC(=O)O)n2)cc1.Cl,,ClCCl,,C1COCCO1,,test
US20110306591A1,Fc1cnc(F)c(C2CCOCC2)c1.O[C@@H]1C[C@H](Nc2nc3ccccc3s2)C1>>Fc1cnc([C@@H]2C[C@@H](Nc3nc4ccccc4s3)C2)c(C2CCOCC2)c1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],[Cl-].[NH4+],test
US20150099734A1,O=C(NCC1(CCl)CCNCC1)N1CCc2[nH]nnc2C1.O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O.OCc1ccc(OC(F)(F)F)cc1>>O=C(NCC1(CCl)CCN(C(=O)OCc2ccc(OC(F)(F)F)cc2)CC1)N1CCc2[nH]nnc2C1,,CC#N,,CCN(CC)CC,Cl,test
US20090197959A1,CC(C)(Oc1ccc(Cl)cc1)C(=O)O.O=C(Cl)C(=O)Cl>>CC(C)(Oc1ccc(Cl)cc1)C(=O)Cl,CN(C)C=O,ClCCl,,CCN(CC)CC,,test
US07728155B2,COc1cc(CC(O)CO)c(OCc2ccccc2)c2c1C1CCC2CC1.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1cc(CC(O)COS(=O)(=O)c2ccc(C)cc2)c(OCc2ccccc2)c2c1C1CCC2CC1,,c1ccncc1,,,,test
US20070269664A1,Cc1nc2c(F)cccc2n1N.Nc1c(F)cccc1[N+](=O)[O-]>>Cc1nc2cccc(F)c2[nH]1,[Fe],CC(=O)O,,CC(=O)OC(C)=O,,test
US20060293319A1,COc1cccc(C2C(=O)Nc3cc(Cl)ccc32)c1.COc1cccc(CBr)c1>>COc1cccc(CC2(c3cccc(OC)c3)C(=O)Nc3cc(Cl)ccc32)c1,,CC(C)=O,CCOC(C)=O,[I-].[K+],,test
US20030199491A1,C1CCNC1.OCCCCl>>OCCCN1CCCC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140364433A1,COc1ccnc(Cl)n1.Cc1nc(C(=O)N2CCC[C@H](C)[C@@H]2CN)c(-c2ccc(F)cc2)s1>>COc1ccnc(NC[C@H]2[C@@H](C)CCCN2C(=O)c2nc(C)sc2-c2ccc(F)cc2)n1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20030100770A1,CC(C)(C)OC(=O)[C@H]1CCCN1C(=O)COc1ccc(OCC(=O)N2CCC[C@@H]2C(=O)OC(C)(C)C)c2ccccc12>>O=C(O)[C@H]1CCCN1C(=O)COc1ccc(OCC(=O)N2CCC[C@@H]2C(=O)O)c2ccccc12,,O=C(O)C(F)(F)F,,,,test
US04479002,CCCCC(CC)COC(=O)NC.ClSCl>>CCCCC(CC)COC(=O)N(C)SCl,,ClCCl,,CCN(CC)CC,,test
US20050113370A1,Cc1cc2c(-c3ccccc3)nn(C(=O)OC(C)(C)C)c2cc1Nc1ccccc1Cl.Cl>>Cc1cc2c(-c3ccccc3)n[nH]c2cc1Nc1ccccc1Cl.Cl,,CCOCC,CO,,,test
US05061720,CCOC(=O)c1ccc(OCCCCl)cc1.O=C1NC(=O)c2ccccc21>>CCOC(=O)c1ccc(OCCCN2C(=O)c3ccccc3C2=O)cc1,,CN(C)C=O,,[K],,test
US20160271081A1,CCOC(=O)C(CCc1ccccc1)CCc1ccccc1>>O=C(O)C(CCc1ccccc1)CCc1ccccc1,,CCO,O,[K+].[OH-],,test
US20040143009A1,CCCCCBr.CCOC(=O)CCN(CC)CC=Cc1ccccc1.CCOCC>>CCCCCC(O)(CCCCC)CCN(CC)CC=Cc1ccccc1,,CCOCC,O,[Mg],[Cl-].[NH4+],test
US20150239845A1,C=CC(=O)OC(C)(C)C.O=c1cc(NC2CCNCC2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2[nH]1>>CC(C)(C)OC(=O)CCN1CCC(Nc2cc(=O)[nH]c3ccc(C(c4ccc(Cl)cc4)c4ccc(Cl)cc4)cc23)CC1,,CO,ClCCl,,,test
US05610293,CCO.Cc1ccc(S(=O)(=O)N2CCCN(S(=O)(=O)c3ccc(C)cc3)CCN(S(=O)(=O)c3ccc(C)cc3)CN(S(=O)(=O)c3ccc(C)cc3)CCN(S(=O)(=O)c3ccc(C)cc3)CC2)cc1>>C1CNCCNCCCNCCNCCNC1,,CCOCC,,O=S(=O)(O)O,,test
US04198527,C=C(C)CCl.OCC(F)(F)F>>C=C(C)COCC(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130259830A1,Cc1[nH]c2c(c1C(O)c1ccccc1S(=O)(=O)N1CCCC1)C(=O)N(C(=O)OC(C)(C)C)CC2>>Cc1[nH]c2c(c1Cc1ccccc1S(=O)(=O)N1CCCC1)C(=O)NCC2,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US05952386,NCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl.O=C(Cl)c1ccc(C(F)(F)F)cc1>>O=C(NCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl)c1ccc(C(F)(F)F)cc1,,ClCCl,,CCN(CC)CC,,test
US20150218171A1,Clc1ccc(-c2cnn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c2)nn1>>Clc1ccc(-c2cn[nH]c2)nn1,,C1CCOC1,,Cl,,test
US05733914,CCn1c(=O)c(-c2c(Cl)cccc2Cl)cc2cnc(S(C)(=O)=O)nc21.COc1ccc(N)cc1OC>>CCn1c(=O)c(-c2c(Cl)cccc2Cl)cc2cnc(Nc3ccc(OC)c(OC)c3)nc21,,CC(=O)O,O,,,test
US20050107435A1,C=CCO.ON=Cc1ccc(Br)cc1>>OCC1CC(c2ccc(Br)cc2)=NO1,,C1CCOC1,,,,test
US20100075948A1,C=CC(C)(C)CC=O.CC(C)(C)OC(=O)CN>>C=CC(C)(C)C/C=N/CC(=O)OC(C)(C)C,,ClCCl,,,,test
US20150203486A1,CCOC(=O)C1CC=C(c2ncc(-c3cn4c(Cc5ccccc5OC(F)F)c(C)nc4cc3F)cn2)CC1>>CCOC(=O)C1CCC(c2ncc(-c3cn4c(Cc5ccccc5OC(F)F)c(C)nc4cc3F)cn2)CC1,,CCO,,,,test
US20110021568A1,CC(=O)O.Oc1c(F)c(F)c(F)c(F)c1F>>CC(=O)Oc1c(F)c(F)c(F)c(F)c1F,,CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20090203629A1,CC(=O)O.CC(C)(C)OC(=O)N[C@H](C=O)CC1CCC1.[C-]#[N+]C1CC1>>CC(=O)OC(C(=O)NC1CC1)[C@H](CC1CCC1)NC(=O)OC(C)(C)C,,ClCCl,,CCOC(C)=O,,test
US20070244106A1,CN1CCN(c2cc(CS(=O)(=O)c3cccc4ccccc34)c([N+](=O)[O-])c(OCCCl)c2)CC1>>CN1CCN(c2cc(CS(=O)(=O)c3cccc4ccccc34)c(N)c(OCCCl)c2)CC1,[Pd],CO,,C1CCOC1,,test
US06492355B1,CC(C)(C)OC(=O)N1CCN(Cc2ccc(Cl)c(C(=O)NCC34CC5CC(CC(C5)C3)C4)c2)CC1.Cl>>Cl.O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(CN2CCNCC2)ccc1Cl,,C1COCCO1,CO,,,test
US20140179680A1,Brc1cccnn1.CCCC[Sn](CCCC)(CCCC)[Sn](CCCC)(CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)c1cccnn1,,C1COCCO1,,ClCCl,,test
US20120202776A1,CP(C)(=O)c1ccc(Nc2ncnc(Cl)n2)cc1.NCCc1ccc(S(N)(=O)=O)cc1>>CP(C)(=O)c1ccc(Nc2ncnc(NCCc3ccc(S(N)(=O)=O)cc3)n2)cc1,,CCO,,CCN(CC)CC,,test
US20110166173A1,CCOC(=O)c1cnc2c(c1)c(I)cn2S(=O)(=O)c1ccccc1.OB(O)c1ccoc1>>CCOC(=O)c1cnc2c(c1)c(-c1ccoc1)cn2S(=O)(=O)c1ccccc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,Cc1ccccc1,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US20160115125A1,COC(=O)c1cc(S(=O)(=O)Cl)cn1C.C[C@H](N)C(F)(F)F>>COC(=O)c1cc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1C,,CC#N,,CCN(C(C)C)C(C)C,,test
US04831055,C1CN1.CC(C)c1ccc(C(=O)Cl)cc1>>CC(C)c1ccc(C(=O)N2CC2)cc1,,c1ccccc1,,CCN(CC)CC,,test
US20100261728A1,FC(F)(F)c1ccc([C@H]2NCCc3ccccc32)cc1.O=C(NC1CCC(F)(F)CC1)Oc1ccc([N+](=O)[O-])cc1>>O=C(NC1CCC(F)(F)CC1)N1CCc2ccccc2[C@H]1c1ccc(C(F)(F)F)cc1,,CC#N,,CO,,test
US20130336920A1,CC(C)(C)OC(=O)CCSCc1cccc(C(=O)O)c1.CC(C)Oc1ccc(N)c(-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1>>CC(C)Oc1ccc(NC(=O)c2cccc(CSCCC(=O)OC(C)(C)C)c2)c(-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US20120157430A1,Brc1ncnc2[nH]cnc12.COc1c(C(C)N)cc(Cl)c(C)c1-c1ccc(C(N)=O)c(F)c1>>COc1c(C(C)Nc2ncnc3[nH]cnc23)cc(Cl)c(C)c1-c1ccc(C(N)=O)c(F)c1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20100311966A1,CO[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1NC(=O)OCc1ccccc1.C[Si](C)(C)N=C=O>>CO[C@@H]1CN(C(N)=O)CC[C@@H]1NC(=O)OCc1ccccc1,,CCOC(C)=O,,CO,Cl,test
US20090105253A1,CCCc1c(C(=O)NC2CC2)nnn1-c1ccc(N)cc1.COCC(=O)O>>CCCc1c(C(=O)NC2CC2)nnn1-c1ccc(NC(=O)COC)cc1,,CC#N,CCN(CC)CC,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US04011335,BrP(Br)Br.C=CC(C)(O)CCC=C(C)CC(C)C>>CC(=CCBr)CCC=C(C)CC(C)C,,CCCCCC,,c1ccncc1,,test
US05171356,N#CN(CC=CCl)CC=CCl>>ClC=CCNCC=CCl,,O,,O=S(=O)(O)O,,test
US20110288066A1,OCCCBr.Sc1cccc(Br)c1>>OCCCSc1cccc(Br)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050256078A1,CCOC(=O)C(C)OP(=O)(CC=CCC(CC(C)=CCc1c(OC)c(C)c2c(c1OCC[Si](C)(C)C)C(=O)OC2)C(=O)OCC[Si](C)(C)C)OC>>CCOC(=O)C(C)OP(=O)(CC=CCC(CC(C)=CCc1c(O)c2c(c(C)c1OC)COC2=O)C(=O)O)OC,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120010182A1,COc1ccc(CN(c2ncccn2)S(=O)(=O)c2cc(Cl)c(F)cc2F)c(OC)c1.Oc1ccc(-c2ccc(C(F)(F)F)cc2)cc1-c1ccnnc1>>COc1ccc(CN(c2ncccn2)S(=O)(=O)c2cc(Cl)c(Oc3ccc(-c4ccc(C(F)(F)F)cc4)cc3-c3ccnnc3)cc2F)c(OC)c1,,CS(C)=O,,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US04927926,CC1(NC(=O)C(F)(F)F)CNC1.O=C(O)c1cn(-c2ccc(F)cc2)c2c(F)c(F)c(F)cc2c1=O>>CC1(NC(=O)C(F)(F)F)CN(c2c(F)cc3c(=O)c(C(=O)O)cn(-c4ccc(F)cc4)c3c2F)C1,,c1ccncc1,,CCN(CC)CC,Cl,test
US20090105213A1,CN(C)C=C1CC(=O)Nc2ccc(I)cc2C1=O.COc1ccc(NC(=N)N)cc1OC>>COc1ccc(Nc2ncc3c(n2)-c2cc(I)ccc2NC(=O)C3)cc1OC,,CCO,O,Cl,O=C([O-])[O-].[K+].[K+],test
US05177210,CC(C)(C)OC(=O)N1CC2CCNC2C1.CCOC(=O)Cl>>CCOC(=O)N1CCC2CN(C(=O)OC(C)(C)C)CC21,,Cc1ccccc1,O,[Na+].[OH-],,test
US20110014271A1,CC(C)(C)OC(=O)N[C@H]1CCN(C(=O)CN(C(=O)/C=C/c2ccccc2)c2ccc(Br)cc2)C1.O=C(O)C(F)(F)F>>N[C@H]1CCN(C(=O)CN(C(=O)/C=C/c2ccccc2)c2ccc(Oc3ccccc3)cc2)C1,,ClCCl,,,,test
US20150366893A1,CON(C)C(=O)C1CC(CC(=O)Nc2cc(C(F)(F)F)ccc2N)C1>>CON(C)C(=O)C1CC(Cc2nc3cc(C(F)(F)F)ccc3[nH]2)C1,,CC(=O)O,,,,test
US20050043388A1,COC(=O)CCc1ccc(C(=O)OC)cc1.COC(=O)c1cccc(CCC(=O)NN)c1.NN>>NNC(=O)CCc1ccc(C(=O)NN)cc1,,CO,,O,O,test
US20030199520A1,COc1cc(C)c(S(=O)(=O)N(Cc2ccc3c(c2)OCO3)[C@H](COC2CCCCO2)C(=O)NOCc2ccccc2)c(C)c1>>COc1cc(C)c(S(=O)(=O)N(Cc2ccc3c(c2)OCO3)[C@H](CO)C(=O)NOCc2ccccc2)c(C)c1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20160272588A1,CCc1c(-c2ccc(O)cc2)cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1Br>>CCc1c(-c2ccc(O)cc2)cnc(N)c1Br,,CCOC(C)=O,,Cl,,test
US20090099205A1,COC(=O)CBr.Sc1ccccn1>>COC(=O)CSc1ccccn1,,CC#N,,CCN(CC)CC,,test
US20060069140A1,CC(=O)c1c(C)nn(-c2ccc(C(C)(C)C)cc2)c1O.NNC(=O)c1ccc(-c2nnn[nH]2)cc1>>CC1=NN(c2ccc(C(C)(C)C)cc2)C(=O)C1=C(C)NNC(=O)c1ccc(-c2nnn[nH]2)cc1,Cl,CN(C)C=O,,,,test
US20090299072A1,CCOC(=O)CC(=O)OCC.O=[N+]([O-])c1c(OCC(F)(F)F)cc(F)cc1OCC(F)(F)F>>CCOC(=O)C(C(=O)OCC)c1cc(OCC(F)(F)F)c([N+](=O)[O-])c(OCC(F)(F)F)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20070032530A1,Cc1nc(-c2ccc(C(F)(F)F)cc2)ccc1CCl.O=S(CCn1ccnn1)Cc1ccc(O)cc1>>Cc1nc(-c2ccc(C(F)(F)F)cc2)ccc1COc1ccc(CS(=O)CCn2ccnn2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20090143361A1,COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)cc(Cl)c4)n3c2n1.N#Cc1cccc(B(O)O)c1>>COc1ccc2nc(C)c3c(C)nc(-c4cccc(C#N)c4)n3c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20080015223A1,Cn1ncc(Br)c1Nc1ccc(I)cc1.OB(O)c1ccc(F)c(F)c1>>Cn1ncc(Br)c1Nc1ccc(-c2ccc(F)c(F)c2)cc1,,CS(C)=O,O,COCCOC,O=C([O-])[O-].[Cs+].[Cs+],test
US20080021217A1,CCOC(=O)C(C)NC(=O)c1cccs1.NN>>CC(NC(=O)c1cccs1)C(=O)NN,,CO,,,,test
US20060074056A1,NO.O=Cc1cc2nccc(Cl)c2s1>>ON=Cc1cc2nccc(Cl)c2s1,,CO,O,Cl,,test
US20100120764A1,NC1CCCCC1.O=C(Cl)c1ccc2nonc2c1>>O=C(NC1CCCCC1)c1ccc2nonc2c1,,ClCCl,,CCN(CC)CC,,test
US20100278878A1,Cc1ccc(C(=O)[C@](O)(C(=O)O)[C@@](O)(C(=O)O)C(=O)c2ccc(C)cc2)cc1.OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1>>Cc1ccc(C(=O)[C@](O)(C(=O)[O-])[C@@](O)(C(=O)[O-])C(=O)c2ccc(C)cc2)cc1.OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1,,CC(C)=O,,,,test
US06413974B1,Clc1nc(Cl)c2ncn(C3CCCC3)c2n1.NCc1ccc(Cl)cc1>>Clc1ccc(CNc2nc(Cl)nc3c2ncn3C2CCCC2)cc1,,CCN(CC)CC,,,,test
US20150105557A1,Clc1ccnc2[nH]ccc12.O=[N+]([O-])O>>O=[N+]([O-])c1c[nH]c2nccc(Cl)c12,,O,,O=S(=O)(O)O,,test
US20060287295A1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.COc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1O>>COc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OC1CCN(C(=O)OC(C)(C)C)CC1,,CC(=O)N(C)C,,[Cs+].[F-],,test
US20150175530A1,COC(=O)[C@@H](NC(=O)c1ccc(C#CC#CC(O)CCO)cc1)C(C)(C)N.NO>>CC(C)(N)[C@H](NC(=O)c1ccc(C#CC#CC(O)CCO)cc1)C(=O)NO,,CC(C)O,,O,,test
US05849921,CI.Cc1ncsc1C(O)c1ccccc1>>COC(c1ccccc1)c1scnc1C,,CN(C)C=O,,[H-].[Na+],,test
US20090170921A1,COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)c(COS(C)(=O)=O)cc(OC)c21.Cc1cn[nH]c1>>COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)c(Cn3cc(C)cn3)cc(OC)c21,,CN(C)C=O,,[H-].[Na+],,test
US20120122843A1,CC(Br)c1ccc(Cl)nc1Cl.NCC(O)C1CC1>>CC(NCC(O)C1CC1)c1ccc(Cl)nc1Cl,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05006511,NCCCN1CCCC1=O.O=C(Cl)OCc1ccccc1>>O=C(NCCCN1CCCC1=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20110224225A1,CCOC(=O)C(C)(Cc1ccc(N2CCN(C)CC2)cc1)C(=O)OCC>>CC(Cc1ccc(N2CCN(C)CC2)cc1)C(=O)O,,Cl,,,,test
US20060084804A1,CNC(=N)SC.O=c1[nH]c2ccc(Br)cc2c(=O)o1>>CNc1nc(=O)c2cc(Br)ccc2[nH]1,,O,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US20080255147A1,CC(C)COC(=O)NC1CCNCC1.Clc1nc(Br)ns1>>CC(C)COC(=O)NC1CCN(c2nc(Br)ns2)CC1,,O,,CN(C)C=O,,test
US20110275611A1,COc1ccc(N)c(N)c1.O=C(O)C1CN(Cc2ccccc2)CCO1>>COc1ccc2[nH]c(C3CN(Cc4ccccc4)CCO3)nc2c1,,Cl,,[Na+].[OH-],,test
US20140020808A1,CO.Nc1ccc(NC(=O)/C=C\C(=O)[O-])cc1.[Na+]>>CO.Nc1ccc(NC(=O)/C=C\C(=O)[O-])cc1.[Na+],,C1CCOC1,,,,test
US20040063680A1,CC(C)S(=O)(=O)NCC(C)(O)c1ccc(OCc2ccccc2)cc1>>CC(C)S(=O)(=O)NCC(C)(O)c1ccc(O)cc1,[Pd],CCOC(C)=O,,[H][H],,test
US05654299,O=C(OCc1ccccc1)N1CC[C@H](c2ccccc2)[C@@H](O)C1>>O[C@H]1CNCC[C@@H]1c1ccccc1,[Pd],CO,,,,test
US20140163024A1,CC(C)CN.O=S(=O)(Cl)c1ccc(CBr)cc1>>CC(C)CNS(=O)(=O)c1ccc(CBr)cc1,,ClCCl,,c1ccncc1,,test
US20160176816A1,CC(C)(C)OC(=O)N1CC[C@@H](COC(=O)Nc2ccccc2-c2ccccc2)C1>>O=C(Nc1ccccc1-c1ccccc1)OC[C@@H]1CCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US03976783,NS(=O)(=O)c1ccc(OCCCl)cc1.c1ccc(CNCCc2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)cc1>>Cl.NS(=O)(=O)c1ccc(OCCN(CCc2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)Cc2ccccc2)cc1,,Cc1ccccc1C,,,,test
US20150225389A1,COc1ccc(CC[C@@]2(C)C(=O)N(C(=O)N[C@H](C)c3ccccc3)[C@@H]2C(=O)OCc2ccccc2)cc1>>COc1ccc(CC[C@@]2(C)C(=O)N(C(=O)N[C@H](C)c3ccccc3)[C@@H]2C(=O)O)cc1,[Pd],CCOC(C)=O,CO,,,test
US05585376,CC1(C)CCCNC1.O=C(Br)CBr>>CC1(C)CCCN(C(=O)CBr)C1,,ClCCl,,CCN(CC)CC,O,test
US04315858,N#CCC(=O)Cl.Nc1ccc(-c2ccc(C(=O)O)c(=O)[nH]2)cc1>>N#CCC(=O)Nc1ccc(-c2ccc(C(=O)O)c(=O)[nH]2)cc1,,ClCCl,,CCN(CC)CC,C[Si](C)(C)Cl,test
US20130085164A1,BrP(Br)Br.CCC(O)c1ccc(-c2cccc(OC)c2)cn1>>CCC(Br)c1ccc(-c2cccc(OC)c2)cn1,,ClC(Cl)Cl,O,,,test
US20070129368A1,COC(=O)c1ccc(/C=C\c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1>>CC1(C)CCC(C)(C)c2cc(/C=C\c3ccc(C(=O)O)cc3)ccc21,,O,,[K+].[OH-],,test
US20070293677A1,CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@@H]2c3cccc4c3c(cn4C(=O)OC(C)(C)C)C[C@H]2N(C(=O)OC(C)(C)C)C1>>CCNC(=O)N(CCCN(C)C)C(=O)[C@H]1CN[C@@H]2Cc3c[nH]c4cccc(c34)[C@H]2C1,,ClCCl,,Cl,N,test
US20100137305A1,CCOC(=O)C1(C)CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(C)(C(=O)O)CC1,,C1CCOC1,CO,[Na+].[OH-],,test
US20040254189A1,CCOC(=O)C(C)(C)c1nc2ccc(Cl)nn2c1C.NCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1>>CCOC(=O)C(C)(C)c1nc2ccc(NCCCN3CCC(OC(c4ccccc4)c4ccccc4)CC3)nn2c1C,,CN1CCCC1=O,,O,,test
US05106871,COCOc1cc(OCOC)c(C(=O)C=Cc2cc(OC)c(OCOC)c(OC)c2)c(O)c1CC=C(C)C>>COCOc1cc(OCOC)c(C(=O)CCc2cc(OC)c(OCOC)c(OC)c2)c(O)c1CCC(C)C,[Pd],CCOC(C)=O,,,,test
US20110218188A1,COCC(=O)Cl.NC(=NO)c1cc(-c2ncnc(Nc3cccc(Cl)c3)n2)ccn1>>COCC(=O)ON=C(N)c1cc(-c2ncnc(Nc3cccc(Cl)c3)n2)ccn1,,CC(C)=O,,O=C([O-])O.[Na+],,test
US20040157804A1,CI.O=C1c2c(c(O)c3c(ncn3Cc3ccccc3)c2OC(c2ccccc2)c2ccccc2)C(=O)N1Cc1ccc(F)cc1>>COc1c2c(c(OC(c3ccccc3)c3ccccc3)c3ncn(Cc4ccccc4)c13)C(=O)N(Cc1ccc(F)cc1)C2=O,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05243049,O=C1OCc2c1c(Cl)nc1ccccc21>>O=C1OCc2c1cnc1ccccc21,[Pd],CC(=O)O,,CC(=O)[O-].[Na+],,test
US20070197512A1,O.O=CCCN1C(=O)C(c2ccccc2)Oc2cc(Cl)ccc21>>O=C(O)CCN1C(=O)C(c2ccccc2)Oc2cc(Cl)ccc21,,CC(C)(C)O,O,CC=C(C)C,[Na+].[O-]Cl,test
US20050020596A1,CN(C)CCNc1ncccc1N.O=C(n1ccnc1)n1ccnc1>>CN(C)CCn1c(=O)[nH]c2cccnc21,,CN(C)C=O,,,,test
US20060235029A1,Cc1ccc(C(=O)Nc2nccs2)cc1-c1nc(NCc2ncc[nH]2)nc2c1ccc(=O)n2-c1c(F)cccc1F.O=S(=O)(O)c1ccccc1>>Cc1ccc(C(=O)Nc2nccs2)cc1-c1nc(NCc2ncc[nH]2)nc2c1ccc(=O)n2-c1c(F)cccc1F.O=S(=O)(O)c1ccccc1,,O,,CC(C)=O,,test
US20120108574A1,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.O=C(Cl)C1CC1>>CC1(C)OB(c2ccc(NC(=O)C3CC3)cc2)OC1(C)C,,ClCCl,,CCN(CC)CC,,test
US20090312314A1,N#CCc1ccc(C(F)(F)F)nc1.Nc1ccc2c(c1)CCCC2>>FC(F)(F)c1ccc(CCNc2ccc3c(c2)CCCC3)cn1,[Pd],CO,,,,test
US20080085890A1,O=Cc1ccn(-c2ccsc2)c(=O)c1>>O=c1cc(CO)ccn1-c1ccsc1,,CO,,[BH4-].[Na+],,test
US20110190278A1,CC(=O)N1C(=O)C(C)(C)c2ccc(Br)cc21>>CC1(C)C(=O)Nc2cc(Br)ccc21,,CCO,,[Na+].[OH-],,test
US04894386,COC(=O)c1ccc(CBr)c(OC)c1.O=C(/C=C/c1ccc2c(/C=C/C(=O)N3CCCC3)c[nH]c2c1)N1CCCC1>>COC(=O)c1ccc(Cn2cc(/C=C/C(=O)N3CCCC3)c3ccc(/C=C/C(=O)N4CCCC4)cc32)c(OC)c1,,CN(C)C=O,,[H-].[Na+],,test
US20150191474A1,CCSc1ccccc1-c1nc(Cl)c2ncc(C(F)(F)F)cc2n1.NN>>CCSc1ccccc1-c1nc(NN)c2ncc(C(F)(F)F)cc2n1,,C1CCOC1,,O,O=C([O-])O.[Na+],test
US20070142464A1,C#C[Mg]Br.O=C(CC1(c2cc(C(F)(F)F)ccc2F)CC1)C(=O)Nc1ccc2c(c1)COC2=O>>C#CC(O)(CC1(c2cc(C(F)(F)F)ccc2F)CC1)C(=O)Nc1ccc2c(c1)COC2=O,,C1CCOC1,,[Cl-].[NH4+],,test
US05556977,COC(=O)COc1ccc(C(=O)CN2CCN(c3ccncc3)CC2)cc1.N>>NC(=O)COc1ccc(C(=O)CN2CCN(c3ccncc3)CC2)cc1,,CO,,,,test
US20130210787A1,C=C(C)[C@@H]1CC[C@]2(CO)CC[C@]3(C)C(CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(C=O)CC[C@]3(C)C(CC[C@@H]4[C@@]5(C)CCC(=O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,CS(C)=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20040033995A1,C=CC(=O)OC.OCCCc1ccccc1>>O=C(O)CCOCCCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US05380925,CCOC(=O)C(C1c2ccccc2C=Cc2ccccc21)[N+](=O)[O-].Cl>>Cl.NC(C(=O)O)C1c2ccccc2CCc2ccccc21,[Pd],CCO,,O,,test
US04367236,CCC(=O)Cl.Cc1c[nH]c(=O)[nH]1>>CCC(=O)c1[nH]c(=O)[nH]c1C,,Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20130281450A1,COC(=O)c1ccc(Oc2ccccc2)c(-c2[nH]c(C)c3c2CCCC3=O)c1>>Cc1[nH]c(-c2cc(C(=O)O)ccc2Oc2ccccc2)c2c1C(=O)CCC2,,C1CCOC1,O,[Na+].[OH-],,test
US04520134,CC(=O)OC(C)=O.CC(C)Nc1ccc(O)cc1>>CC(=O)N(c1ccc(O)cc1)C(C)C,,CC(=O)O,,[Na+].[OH-],,test
US20090240052A1,COc1cccc(/C=C/c2ccc(C(=O)OC(C)(C)C)c(NC(=O)c3cccc(C)c3C)c2)c1>>COc1cccc(/C=C/c2ccc(C(=O)O)c(NC(=O)c3cccc(C)c3C)c2)c1,,O=C(O)C(F)(F)F,,,,test
US20070088036A1,C1CCNC1.Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)N1CCC(C(=O)O)(c2ccc(Cl)cc2)CC1>>Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)N1CCC(C(=O)N2CCCC2)(c2ccc(Cl)cc2)CC1,,CN1CCCC1=O,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US20120022060A1,Cl.Clc1cnc2[nH]c3c(c2c1)CNCC3.O=C=Nc1cccc(Cl)c1>>Cl.O=C(Nc1cccc(Cl)c1)N1CCc2[nH]c3ncc(Cl)cc3c2C1,,CCOCC,ClCCl,CCN(C(C)C)C(C)C,,test
US20110152273A1,CC(C)(C)OC(=O)N[C@H]1CCC[C@H]1N.COC(=O)c1c(C#N)cc(Cl)nc1Nc1cccc(S(C)(=O)=O)c1>>COC(=O)c1c(C#N)cc(N[C@@H]2CCC[C@@H]2NC(=O)OC(C)(C)C)nc1Nc1cccc(S(C)(=O)=O)c1,,CN(C)C=O,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20080275037A1,Cc1ccc(N2CCc3ncnc(Cl)c3C2)c(C#N)c1.NCc1ccc2ccccc2n1>>Cc1ccc(N2CCc3ncnc(NCc4ccc5ccccc5n4)c3C2)c(C#N)c1,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20020042409A1,Cc1cc2cc(N)ccc2[nH]1.O=C(c1cc2nccc(Cl)c2s1)N1CCCC1>>Cc1cc2cc(Nc3ccnc4cc(C(=O)N5CCCC5)sc34)ccc2[nH]1,,CCO,,,,test
US04507296,[N-]=[N+]=NCC(O)CCOc1cccc(CN2CCCCC2)c1>>NCC(O)CCOc1cccc(CN2CCCCC2)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100137250A1,ClC(Cl)(Cl)Cl.O=S(=O)(c1ccccc1)c1ccc(CO)cc1>>O=S(=O)(c1ccccc1)c1ccc(CCl)cc1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090227648A1,C[C@H](N)c1ccc(F)cc1.N#Cc1cc([N+](=O)[O-])c(Nc2cc(C3CC3)[nH]n2)cc1F>>C[C@H](Nc1cc(Nc2cc(C3CC3)[nH]n2)c([N+](=O)[O-])cc1C#N)c1ccc(F)cc1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US05011931,CNc1cc(F)ccc1C(=O)CS(C)=O>>CNc1cc(F)ccc1C(C)=O,[Zn],CC(=O)O,,CCO,,test
US20090111811A1,COC(=O)c1ccc(-c2nnc(N3CCC[C@@H]3c3cc(-c4cccc(Cl)c4)on3)n2C)cc1>>Cn1c(-c2ccc(C(=O)O)cc2)nnc1N1CCC[C@@H]1c1cc(-c2cccc(Cl)c2)on1,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20110021516A1,C[Si](C)(C)CCOCN1C(=O)Cc2cccnc21.Clc1cc(CBr)c(CBr)cn1>>C[Si](C)(C)CCOCN1C(=O)C2(Cc3cnc(Cl)cc3C2)c2cccnc21,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US03970592,C=C(C)C=CCCC(=C)C>>C=C(C)CC=CC=C(C)C,,CC(C)O,,O=P(O)(O)O,,test
US04753935,CC(=O)OC(C)=O.COc1c(C)c2c(c(O)c1C/C=C(\C)CCC(=O)OCCN1CCOCC1)C(=O)OC2>>COc1c(C)c2c(c(OC(C)=O)c1C/C=C(\C)CCC(=O)OCCN1CCOCC1)C(=O)OC2,,c1ccncc1,,O,,test
US20110062165A1,CC(C)(C)[Si](C)(C)OCc1cc(Cl)cc(CCl)c1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>OCc1cc(Cl)cc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c1.[Cl-],,Cc1ccccc1,,,,test
US20070135385A1,CCCCCCCCCCCC(Br)Br.CCOC(=O)C(Oc1cccc2[nH]c(C)cc12)C(C)C>>CCOC(=O)C(Oc1cccc2c1cc(C)n2CCCCCCCCCCCCBr)C(C)C,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20150210727A1,CC(=O)c1cccc(C(C)(C)N)c1.O=C(Cl)Oc1ccc(Cl)cc1>>CC(=O)c1cccc(C(C)(C)NC(=O)Oc2ccc(Cl)cc2)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070191336A1,CCOC(=O)c1cccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccccc2F)c1>>CC(C)(C)c1cc(NC(=O)Nc2ccccc2F)n(-c2cccc(CO)c2)n1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06127354,CN(CCc1ccccc1OCCCO)C(=O)[C@@H](Cc1ccc2ccccc2c1)N(C)C(=O)OC(C)(C)C>>CN[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)CCc1ccccc1OCCCO,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US05922725,N#Cc1ccc2c(c1)ncn2-c1cccc(-c2nccs2)c1.O=CO>>O=Cc1ccc2c(c1)ncn2-c1cccc(-c2nccs2)c1,[Ni],O,,,,test
US20060173022A1,CC(C)(C)OC(=O)NCCN.O=C(Cl)c1cnccc1C(F)(F)F>>CC(C)(C)OC(=O)NCCNC(=O)c1cnccc1C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20100035942A1,COC(=O)CBr.Nc1c(F)cc(Br)cc1OCc1ccccc1>>COC(=O)CNc1c(F)cc(Br)cc1OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140163000A1,CC(C)(C)OC(=O)NC1CCN(c2ccncc2[N+](=O)[O-])CC1.CI>>CN(C(=O)OC(C)(C)C)C1CCN(c2ccncc2N)CC1,[Pd],CN(C)C=O,CO,[H-].[Na+],,test
US06204277B1,COC(=O)CCc1ccc(OCCc2nc(-c3cc4ccccc4s3)oc2C)cc1>>Cc1oc(-c2cc3ccccc3s2)nc1CCOc1ccc(CCC(=O)O)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20090137557A1,C=C(C)CC(C(C)=O)C(=O)NCCc1ccccc1>>CC(=O)C(CC(C)C)C(=O)NCCc1ccccc1,[Pd],CCOC(C)=O,,CCO,,test
US20090203737A1,COC(=O)C1=CC(C)(C)CN(C(=O)c2ccc(F)cc2)C1>>COC(=O)C1CN(C(=O)c2ccc(F)cc2)CC(C)(C)C1,[Pd],CCO,,,,test
US20150031674A1,CCN.Cc1cncc(-c2ccc(-c3cc4cnc(S(C)=O)nc4n(CCOC4CN(C(=O)OC(C)(C)C)C4)c3=O)c(Cl)c2)n1>>CCNc1ncc2cc(-c3ccc(-c4cncc(C)n4)cc3Cl)c(=O)n(CCOC3CN(C(=O)OC(C)(C)C)C3)c2n1,,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US04192953,C1CCOC1.CC(=O)O.COC(OC)C(=O)CCC=C(C)CCC=C(C)CCC=C(C)C.[Li]CCCC>>CC(C)=CCCC(C)=CCCC(C)=CCCC(C=O)=CCCC(C)=CCOC1CCCCO1,,C1CCOC1,,,,test
US20040254217A1,NC(=O)C=Cc1ccc(Cl)c(Cl)c1.O=C(CCl)CCl>>ClCc1coc(C=Cc2ccc(Cl)c(Cl)c2)n1,,Cc1ccccc1,,,,test
US04560701,CC(CCCO)c1ccc(OCc2ccsc2C(=O)O)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC(CCCOC(=O)C(F)(F)F)c1ccc2c(c1)C(=O)c1sccc1CO2,,O,,ClCCl,,test
US20070155726A1,CNCCNC.COC(=O)c1ccc(CBr)cc1>>CNCCN(C)Cc1ccc(C(=O)OC)cc1,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US05166214,BrCCCCCCBr.C[Si](C)(C)CCOCn1cnc(-c2ccccc2)c1-c1ccccc1>>C[Si](C)(C)CCOCn1c(CCCCCCBr)nc(-c2ccccc2)c1-c1ccccc1,,C1CCOC1,O,CCCCCC,[Li]CCCC,test
US04820729,CC(=O)C(=O)O.CCO.Cc1ccc(CN(CC(=O)O)C(=O)[C@H](C)NC(=O)OCc2ccccc2)cc1>>CC(=O)C(=O)O.Cc1ccc(CN(CC(=O)O)C(=O)[C@H](C)NC(C)C(=O)O)cc1,[Pd],CCO,,,,test
US20160075711A1,COP(=O)(CC(=O)C1CCCCC1)OC.COc1cc(C=O)c(-c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)cn1>>COc1cc(C=CC(=O)C2CCCCC2)c(-c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)cn1,,C1CCOC1,,[BH4-].[Na+],,test
US04883653,C1COCCO1.Cc1ccc(N)cc1N.O.O=C(Cl)C=Cc1ccccc1.c1ccncc1>>Cc1ccc(NC(=O)C=Cc2ccccc2)cc1NC(=O)C=Cc1ccccc1,,C1COCCO1,,,,test
US20130029971A1,CCOC(=O)CC1CCN(c2nc(S(C)(=O)=O)ccc2[N+](=O)[O-])CC1>>CCOC(=O)CC1CCN(c2nc(S(C)(=O)=O)ccc2N)CC1,[Pd],CCO,,,,test
US20040214864A1,CS(N)(=O)=O.O=C(O)c1ccc(-c2nn(Cc3cccc(Cl)c3)c(=S)[nH]2)cc1>>CS(=O)(=O)NC(=O)c1ccc(-c2nn(Cc3cccc(Cl)c3)c(=S)[nH]2)cc1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20070066618A1,CCOC(=O)Cc1ccc([N+](=O)[O-])nc1>>Nc1ccc(CCO)cn1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150307470A1,CC1(C)OB(c2cccc(Cl)n2)OC1(C)C.COC(=O)c1cccnc1Br>>COC(=O)c1cccnc1-c1cccc(Cl)n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US20050113379A1,COC[C@H](C)Nc1cnc(-c2ccc(C(C)C)nc2OC)c(C)c1C.O=C1CCC(=O)N1Br>>COC[C@H](C)Nc1c(Br)nc(-c2ccc(C(C)C)nc2OC)c(C)c1C,,ClC(Cl)Cl,,O,,test
US20060205751A1,CCOC(=O)c1cccc(-c2cc3cc(Cl)ccc3o2)c1>>O=C(O)c1cccc(-c2cc3cc(Cl)ccc3o2)c1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20060194843A1,CCOC(=O)c1n[nH]cc1-c1ccc(Cl)cc1Cl>>O=C(O)c1n[nH]cc1-c1ccc(Cl)cc1Cl,,C1CCOC1,O,[Li+].[OH-],,test
US20140179680A1,C=C(I)CO.CC(C)(C)[Si](C)(C)Cl>>C=C(I)CO[Si](C)(C)C(C)(C)C,,ClCCl,,c1c[nH]cn1,,test
US20090233937A1,O=C1CCC(=O)O1.OCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(Cl)c3)c21>>O=C(O)CCC(=O)OCCn1ccc2ncnc(Nc3ccc(Oc4cccc5sncc45)c(Cl)c3)c21,,CN1CCCC1=O,,CCN(CC)CC,[Cl-].[NH4+],test
US20030065179A1,CCCC(=O)O[C@H](C)c1nccc(N2CCC(=Cc3cccc(Cl)c3)CC2)n1>>C[C@@H](O)c1nccc(N2CCC(=Cc3cccc(Cl)c3)CC2)n1,,CO,ClC(Cl)Cl,[Na+].[OH-],,test
US20090176786A1,C=O.CO.Nc1ccc(SC(F)(F)F)cc1F>>COCNc1ccc(SC(F)(F)F)cc1F,,CO,,C[O-].[Na+],,test
US06511974B1,Cc1cn[nH]c1.O=C(c1ccc(F)cc1C(F)(F)F)N1Cc2cccn2Cc2ccccc21>>Cc1cnn(-c2ccc(C(=O)N3Cc4cccn4Cc4ccccc43)c(C(F)(F)F)c2)c1,,CN(C)C=O,,[H-].[Na+],,test
US05874427,COC(OC)N(C)C.Cc1nc(Cl)ccc1[N+](=O)[O-]>>CN(C)C=Cc1nc(Cl)ccc1[N+](=O)[O-],CCN(CC)CC,CN(C)C=O,,,,test
US20140018313A1,COC(=O)NC(C(=O)N1CCCC1c1nc2ccc3cc(-c4ccc5cc(-c6cnc(C7CCCN7C(=O)C(N)c7ccccc7)[nH]6)ccc5c4)ccc3c2[nH]1)C(C)C.O=C(Oc1ccc([N+](=O)[O-])cc1)OC1COC1>>COC(=O)NC(C(=O)N1CCCC1c1nc2ccc3cc(-c4ccc5cc(-c6cnc(C7CCCN7C(=O)C(NC(=O)OC7COC7)c7ccccc7)[nH]6)ccc5c4)ccc3c2[nH]1)C(C)C,,CC#N,,CCN(C(C)C)C(C)C,,test
US20020137974A1,Brc1ccccc1.Sc1ccccc1>>c1ccc(Sc2ccccc2)cc1,,Cc1ccccc1,,CC(C)(C)O[Na],,test
US20140113901A1,CC(C)(C)OC(=O)NC1(c2ccc(C(=O)C(Br)c3ccccc3)cc2)CCC1.Cc1ccc(N)nn1>>Cc1ccc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)n2n1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20100216750A1,O=C(O)CCCOCCc1ccccc1.c1ccc(-c2cnco2)nc1>>O=C(CCCOCCc1ccccc1)c1ncc(-c2ccccn2)o1,,CO,ClCCl,,,test
US20100317848A1,O=C(N[C@@]1(C(=O)O)CCOC1)c1ccc(Cl)s1>>O=C1OC(c2ccc(Cl)s2)=N[C@]12CCOC2,,CC(=O)OC(C)=O,,,,test
US20160176858A1,COC(=O)C(NC(=O)[C@@H]1CC[C@@H](C)N(C(=O)c2ccccc2-n2nccn2)C1)C(=O)c1ccccc1>>C[C@@H]1CC[C@@H](c2nc(C(=O)O)c(-c3ccccc3)o2)CN1C(=O)c1ccccc1-n1nccn1,,C1CCOC1,O,[Li]O,,test
US04654343,CC(=O)Nc1cccc(-c2ccc3nnc(C)n3n2)c1.CCCBr>>CCCN(C(C)=O)c1cccc(-c2ccc3nnc(C)n3n2)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20040038967A1,C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(c3cn4cnc(C(=O)c5cccnc5)c4s3)[C@H](C)[C@H]12.NC(=O)CI>>C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(c3cn4cnc(C(=O)c5ccc[n+](CC(N)=O)c5)c4s3)[C@H](C)[C@H]12.[I-],,CC#N,,,,test
US20130310438A1,COC(=O)CCC[C@H]1CC[C@H]2[C@H](C[C@@H](OC3CCCCO3)[C@@H]2C=O)S1.COP(=O)(CC(=O)COc1ccccc1)OC>>COC(=O)CCC[C@H]1CC[C@H]2[C@H](C[C@@H](OC3CCCCO3)[C@@H]2/C=C/C(=O)COc2ccccc2)S1,,CC(=O)O,CCOC(C)=O,C1CCOC1,[H-].[Na+],test
US20020099055A1,COC(=O)CCCSc1c(Cc2cccc3ccccc23)sc2c(CC(C)C)nn(C)c(=O)c12>>CC(C)Cc1nn(C)c(=O)c2c(SCCCC(=O)O)c(Cc3cccc4ccccc34)sc12,,C1CCOC1,O,Cl,[Li+].[OH-],test
US04728645,CCOC(=O)c1ccc(-c2cccc3cncn23)cc1.Cl>>CCOC(=O)c1ccc(C2CCCc3cncn32)cc1.Cl,[Pd],CCO,,[H][H],,test
US20120083469A1,C=CCCC(CO)(NC(=O)OC(C)(C)C)C(=O)OCC.CC(=O)OC(C)=O>>C=CCCC(COC(C)=O)(NC(=O)OC(C)(C)C)C(=O)OCC,,ClCCl,,CN(C)c1ccccn1,,test
US20130072467A1,NCC(=O)NC1CC1.O=C1NC(=S)CS1>>O=C(CNC1=NC(=O)SC1)NC1CC1,,CCO,,,,test
US20140303186A1,CCOC(=O)Cc1nn(Cc2ccc([N+](=O)[O-])cc2)c2cc(F)ccc12>>CCOC(=O)Cc1nn(Cc2ccc(N)cc2)c2cc(F)ccc12,[Pd],CO,,CCOC(C)=O,,test
US05587486,C=CC(=O)OC.CCOC(=O)Cl.Cc1ccccc1.Cc1ccoc1C=N>>CCOC(=O)N(c1ccccc1)C1c2occc2CCC1C(=O)OC,,O,,CCN(C(C)C)C(C)C,,test
US20140249126A1,COc1ccc(COc2cn(C)c3ccc(CO)cc3c2=O)cc1>>COc1ccc(COc2cn(C)c3ccc(C=O)cc3c2=O)cc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US20030144263A1,CCOC(=O)Cl.N#Cc1ccn(-c2ccc(N)cc2F)c1>>CCOC(=O)Nc1ccc(-n2ccc(C#N)c2)c(F)c1,,c1ccncc1,,,,test
US20110237584A1,CC(C)[Mg]Br.O=Cc1cccnc1>>CC(C)C(O)c1cccnc1,,C1CCOC1,,,,test
US20130085151A1,CCCC[Sn](CCCC)(CCCC)c1ccccn1.Cc1cc2cc([C@H](C)N3C(=O)c4ccccc4C3=O)c(Cl)nc2s1>>Cc1cc2cc([C@H](C)N3C(=O)c4ccccc4C3=O)c(-c3ccccn3)nc2s1,,C1COCCO1,CCOC(C)=O,,,test
US04343945,Nc1nc(C(Cl)(Cl)Cl)ns1.O=C(Cl)c1ccccc1F>>O=C(Nc1nc(C(Cl)(Cl)Cl)ns1)c1ccccc1F,,Cc1ccccc1C,,,,test
US20150284335A1,COC(=O)c1nc2cc(N)ccc2[nH]1.O=C(Cl)c1ccccc1>>COC(=O)c1nc2cc(NC(=O)c3ccccc3)ccc2[nH]1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20030149001A1,C=C(OCC)c1c(C)c2cnc(Nc3ccc(N4CCN(C)CC4)cn3)nc2n(C2CCCC2)c1=O>>CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCN(C)CC4)cn3)nc2n(C2CCCC2)c1=O,,ClC(Cl)Cl,,Cl,,test
US04886794,Cc1ccc(C(O)(c2ccc(C)cc2)C2CCN(Cc3ccccc3)CC2)cc1>>Cc1ccc(C(O)(c2ccc(C)cc2)C2CCNCC2)cc1,[Pd],CCO,,,,test
US20110053916A1,N#CCc1ccc(-c2nccc(OCc3ccccc3)n2)cc1>>N#CCc1ccc(-c2nccc(O)n2)cc1,,O=C(O)C(F)(F)F,,,,test
US05028728,O=[N+]([O-])c1cc(C(c2ccc(Nc3ccccc3)c([N+](=O)[O-])c2)(C(F)(F)F)C(F)(F)F)ccc1Nc1ccccc1>>Nc1cc(C(c2ccc(Nc3ccccc3)c(N)c2)(C(F)(F)F)C(F)(F)F)ccc1Nc1ccccc1,[Pd],CCO,,[H][H],,test
US20110263598A1,C[S+](C)(C)=O.C[Si](C)(C)CCOCn1nc(I)c2ccc(/C=C3/C(=O)Nc4ccc(F)cc43)cc21>>C[Si](C)(C)CCOCn1nc(I)c2ccc([C@@H]3C[C@@]34C(=O)Nc3ccc(F)cc34)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20040116518A1,CC(=O)N1CCN(C(=O)/C=C/c2ccc(Sc3cc(N)c([N+](=O)[O-])cc3Cl)c(Cl)c2)CC1>>CC(=O)N1CCN(C(=O)/C=C/c2ccc(Sc3cc(N)c(N)cc3Cl)c(Cl)c2)CC1,,CCO,,Cl[Sn]Cl,,test
US04999356,C=CCBr.c1ccc(-n2nc(N3CCNCC3)c3ccccc32)cc1>>C=CCN1CCN(c2nn(-c3ccccc3)c3ccccc23)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04435397,BrCC1CO1.Cc1ccc(O)c2oc(=O)ccc12>>Cc1ccc(OCC2CO2)c2oc(=O)ccc12,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05231102,COC(=O)[C@H]1C[C@H](NCc2ccccc2)c2c(Cl)cc(Cl)cc2N1>>O=C(O)[C@H]1C[C@H](NCc2ccccc2)c2c(Cl)cc(Cl)cc2N1,,CS(C)=O,,,,test
US04590201,Cc1cc(C)cc(C)c1.O=C(Cl)c1ccc(Cl)cc1>>Cc1cc(C)c(C(=O)c2ccc(Cl)cc2)c(C)c1,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100204442A1,COC(=O)C(CCCCCCOc1ccc([N+](=O)[O-])cc1)C(=O)OC>>Nc1ccc(OCCCCCCC(CO)CO)cc1,,C1CCOC1,,CO,[BH4-].[Li+],test
US20130338196A1,COC(=O)C1CCc2cc(O)ccc2C1.OCc1ccccc1>>COC(=O)C1CCc2cc(OCc3ccccc3)ccc2C1,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110237791A1,Br.COc1nc(C(=C[C@H]2CCC(=O)N2)c2ccc(COCCC(C)C)cc2)ccc1Cl>>O=C1CC[C@H](C=C(c2ccc(CBr)cc2)c2ccc(Cl)c(=O)[nH]2)N1,,CC#N,,O,O=C([O-])O.[Na+],test
US20100317651A1,CCC(C)N(C)c1cnc(CN(CCO)Cc2ccccc2)c(Cl)n1>>CCC(C)N(C)c1cnc2c(n1)OCCN(Cc1ccccc1)C2,,CN(C)C=O,,O,CC(C)(C)[O-].[K+],test
US20150080549A1,CC(C)(C)SSCC(O[Si](C)(C)C(C)(C)C)C(=O)O.N#CCBr>>CC(C)(C)SSCC(O[Si](C)(C)C(C)(C)C)C(=O)OCC#N,,CCOCC,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20110250135A1,CC(=O)Oc1ccc(C(=O)CCC(=O)O)cc1.O=[N+]([O-])c1ccc(N2CCNCC2)cc1>>CC(=O)Oc1ccc(C(=O)CCC(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140088075A1,CCn1c(=O)c(-c2cc(N)c(F)cc2F)cc2cnc(N)cc21.O=C=Nc1ccccc1>>CCn1c(=O)c(-c2cc(NC(=O)Nc3ccccc3)c(F)cc2F)cc2cnc(N)cc21,,ClCCl,,,,test
US20100197678A1,Fc1ccc(-n2ncc3cc(Br)ccc32)cc1.O=C(c1c[nH]c2ccccc12)C(F)(F)F>>OC(c1ccc2c(cnn2-c2ccc(F)cc2)c1)(c1c[nH]c2ccccc12)C(F)(F)F,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20090197871A1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)O)c1.NCc1ccc(F)c(Br)c1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(F)c(Br)c2)c1,,ClCCl,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20150166564A1,O=C(Nc1c2c(nn1-c1ccccc1)CCC2)N[C@@H]1CNC[C@H]1c1cccc(Cl)c1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>O=C(Nc1c2c(nn1-c1ccccc1)CCC2)N[C@@H]1CN(CC(F)(F)F)C[C@H]1c1cccc(Cl)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20090099206A1,COc1cccc(-c2ccc([C@@H](Oc3cc(-c4ccc(C[C@H](N)C(=O)[O-])cc4)nc(N)n3)C(F)(F)F)cc2)c1.O=C(O)/C=C\C(=O)O>>COc1cccc(-c2ccc([C@@H](Oc3cc(-c4ccc(C[C@H](N)C(=O)O)cc4)nc(N)n3)C(F)(F)F)cc2)c1.O=C(O)/C=C\C(=O)O,,CO,,,,test
US20160024083A1,CC(=O)OC(C)=O.CCCn1c2ccc(O)cc2c2cc(C(C)=O)ccc21>>CCCn1c2ccc(OC(C)=O)cc2c2cc(C(C)=O)ccc21,,ClC(Cl)Cl,ClCCl,c1ccncc1,,test
US20080146566A1,Cc1ccc(C(=O)O)cc1-n1cc(C)c2ccc(O)cc2c1=O.ClCCBr>>Cc1ccc(C(=O)O)cc1-n1cc(C)c2ccc(OCCCl)cc2c1=O,,CN(C)C=O,,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20100009969A1,CC1CCCN1.O=C(NC1Cc2nc(-c3ccc(OCCCCl)cc3)sc2C1)OCc1ccccc1>>CC1CCCN1CCCOc1ccc(-c2nc3c(s2)CC(NC(=O)OCc2ccccc2)C3)cc1,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US20100125062A1,CC(=O)N1CC=C(c2cccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)CC1>>CC(=O)N1CCC(c2cccnc2Oc2ccc(C(O)c3nc4ccccc4[nH]3)cc2)CC1,[Pd],C1CCOC1,,CC(=O)O,,test
US20160257658A1,Cc1ccc(C(=O)CBr)cc1Br.NC(N)=S>>Cc1ccc(-c2csc(N)n2)cc1Br,,CCO,,,,test
US20130336921A1,O=[N+]([O-])c1ncn(-c2cccc(C(F)(F)F)c2)n1>>Nc1ncn(-c2cccc(C(F)(F)F)c2)n1,[Pd],CO,,,,test
US08652353B2,CCCCCc1ccc(I)cc1.OB(O)c1cccc(F)c1F>>CCCCCc1ccc(-c2cccc(F)c2F)cc1,,CC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US05389658,Cl.NCCCSc1ccncc1.O=C(Cl)c1ccc(-c2ccccc2)cc1>>Cl.O=C(NCCCSc1ccncc1)c1ccc(-c2ccccc2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20090209529A1,Brc1cccc(Br)c1.CC(=O)c1ccc(OC2CCCCO2)cc1>>C=C(c1ccc(O)cc1)c1cccc(Br)c1,,C1CCOC1,,Cl,[Li]CCCC,test
US20130237535A1,CCO/C=C/C(=O)OCC.Nc1cc(Br)ccc1C=O>>CCOC(=O)c1cnc2cc(Br)ccc2c1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20050075334A1,CN(C)C(=O)Sc1cccc2[nH]c(=O)[nH]c12>>O=c1[nH]c2cccc(S)c2[nH]1,,O,,CC(=O)O,[Na+].[OH-],test
US05420151,CC(C)=O.COc1cccc2c1C[C@@H](N)CO2>>COc1cccc2c1C[C@@H](NC(C)C)CO2,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US20150166564A1,CC(C)(C)OC(=O)N1C[C@@H](c2ccccc2)[C@H](NC(=O)Nc2c3c(nn2-c2ccccc2)CCC3)C1.Cl>>Cl.O=C(Nc1c2c(nn1-c1ccccc1)CCC2)N[C@@H]1CNC[C@H]1c1ccccc1,,C1COCCO1,,,,test
US20090093456A1,COC(=O)c1sc(-c2ccc(Cl)cc2)cc1C#C[Si](C)(C)C.COc1cc(N)ccc1OC1CN(C(=O)OC(C)(C)C)C1>>COc1cc(NC(=O)c2sc(-c3ccc(Cl)cc3)cc2C#C[Si](C)(C)C)ccc1OC1CN(C(=O)OC(C)(C)C)C1,,Cc1ccccc1,,C[Al](C)C,,test
US04788206,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.COc1ccc(/C(C)=C/C=O)cc1>>COC(=O)/C=C/C=C(\C)c1ccc(OC)cc1,,ClC(Cl)(Cl)Cl,ClCCl,,,test
US20120065214A1,COc1ccccc1C1(C(N)=O)CCC1>>NC(=O)C1(c2ccccc2O)CCC1,,ClCCl,,BrB(Br)Br,,test
US20140200207A1,C[Si](C)(C)CCOCn1cc(I)c2c(OC3CCOCC3)nc(Cl)nc21.OB(O)c1ccncc1>>C[Si](C)(C)CCOCn1cc(-c2ccncc2)c2c(OC3CCOCC3)nc(Cl)nc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20140249244A1,O=C(O)Cc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]>>O=[N+]([O-])c1ccc(CCO)c([N+](=O)[O-])c1,,C1CCOC1,,CCOC(C)=O,O,test
US05747525,NC=C(O)CO.O=Cc1ccc(-c2cccs2)s1>>OCC(O)CN=C=C1CC=C(c2cccs2)S1,,c1ccccc1,,,,test
US20030013730A1,CN1CCNCC1.Cc1cccc2nc(S)oc12>>Cc1cccc2nc(N3CCN(C)CC3)oc12,,Cc1ccccc1,,ClP(Cl)(Cl)(Cl)Cl,,test
US05629406,CC(C)(C)NC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C.Cl>>CC(C)(C)NC(=O)[C@@H]1CCCN1.Cl,,C1COCCO1,,,,test
US20150152118A1,CCOC(=O)OCC.O=C1CCC2(CC1)CC2>>CCOC(=O)C1CC2(CCC1=O)CC2,,CN(C)C=O,,[H-].[Na+],,test
US20090137603A1,CCOC(=O)c1nc2scc(C)c2c(=O)[nH]1.O=C1CCC(=O)N1Br>>CCOC(=O)c1nc2scc(CBr)c2c(=O)[nH]1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20140206663A1,CC(=O)c1cc2c(cc1F)OCC(=O)N2.CCOC(=O)C(C)Br>>CCOC(=O)C(C)N1C(=O)COc2cc(F)c(C(C)=O)cc21,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140315889A1,Cc1cn(C(=O)OC(C)(C)C)c2c1C(=O)NCC2.ClCCN1CCOCC1>>Cc1cn(C(=O)OC(C)(C)C)c2c1C(=O)N(CCN1CCOCC1)CC2,,CN(C)C=O,,Cl,[H-].[Na+],test
US06117888,CCOC(=O)CBr.O=[N+]([O-])c1c(Cl)ccnc1O>>CCOC(=O)Cn1ccc(Cl)c([N+](=O)[O-])c1=O,,C1CCOC1,,[H-].[Na+],,test
US20130102776A1,C=O.CC(C)(C)OC(=O)N1CCNCC1.O=C1COc2cc(O)c(Cl)cc21>>CC(C)(C)OC(=O)N1CCNCC1Cc1c(O)c(Cl)cc2c1OCC2=O,,CCO,,,,test
US20100240620A1,CCC(=O)C(=Cc1ccc(C#N)cc1OC)c1nc(C)cs1.N#CC=C(N)C(F)(F)F>>CCC1=C(c2nc(C)cs2)C(c2ccc(C#N)cc2OC)C(C#N)=C(C(F)(F)F)N1,,CC(C)O,,CC(C)(C)[O-].[K+],,test
US20150299181A1,CC(=O)c1ccc2oc(C#N)cc2c1.CCCc1ccc(N)cc1Cl>>CCCc1ccc(NC(C)c2ccc3oc(C#N)cc3c2)cc1Cl,CC(C)O[Ti](OC(C)C)(OC(C)C)OC(C)C,ClCCl,,[BH4-].[Na+],,test
US20090192156A1,CCOC1CCNCC1.COc1cccc2c(=O)[nH]nc(Cc3ccc(F)c(C(=O)O)c3)c12>>CCOC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4cccc(OC)c34)ccc2F)CC1,,CC#N,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120225854A1,CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)C[C@@H]2COS(C)(=O)=O)cc1)C(F)(F)F.Nc1ccccc1>>CC(O)(c1ccc(N2CCN(S(=O)(=O)c3cccs3)C[C@@H]2CNc2ccccc2)cc1)C(F)(F)F,,CO,,,,test
US20070015784A1,C[Si](C)(C)Cl.O=C(COc1ccccc1)N1CCC2(CC1)N[C@@H](Cc1ccccc1)C(=O)N2Cc1ccccc1>>Cl.O=C(COc1ccccc1)N1CCC2(CC1)N[C@@H](Cc1ccccc1)C(=O)N2Cc1ccccc1,,CCC(C)=O,,CCOCC,O,test
US20150337004A1,CC1(C)CC(=O)OC1=O.CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2CC[C@@H]2[C@H]3[C@H](C4(C)CC4)CC[C@]3(C(=O)N3CCC[C@@H]3c3ncc(-c4ccccc4)[nH]3)CC[C@]21C>>CC(C)(CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC[C@@H]2[C@H]4[C@H](C5(C)CC5)CC[C@]4(C(=O)N4CCC[C@H]4c4ncc(-c5ccccc5)[nH]4)CC[C@]23C)C1(C)C)C(=O)O,CN(C)c1ccncc1,CCOC(C)=O,Cc1ccccc1,,,test
US04447441,CCOC(=O)CCCSc1nccc(NC(N)=NCC(F)(F)F)n1.NCCO>>NC(=NCC(F)(F)F)Nc1ccnc(SCCCC(=O)NCCO)n1,,CO,,,,test
US20100010115A1,CC(C)=O.O=C1NC(=O)N(Cc2ccccc2)C(=O)C1c1ccccc1>>CC(C)=O.O=C1NC(=O)N(Cc2ccccc2)C(=O)C1c1ccccc1,,CC(C)=O,,O,,test
US20100099715A1,CCCCn1ccc(Br)c(C#N)c1=O.Cc1cc(Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2F)cc(C)n1>>CCCCn1ccc(-c2ccc(Oc3cc(C)nc(C)c3)c(F)c2)c(C#N)c1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])O.[Na+],,test
US20120270838A1,O=C1NC(C2CCCCC2)=NC12CCN(S(=O)(=O)CCc1cccc([N+](=O)[O-])c1)CC2>>Nc1cccc(CCS(=O)(=O)N2CCC3(CC2)N=C(C2CCCCC2)NC3=O)c1,[Pd],CCO,,,,test
US20080160028A1,CCO.Cc1nc(-c2ccccc2)nc2sc3c(N4CCNCC4)nc(Cl)nc3c12>>CCOc1nc(N2CCNCC2)c2sc3nc(-c4ccccc4)nc(C)c3c2n1,,CCO,,C,C[O-].[Na+],test
US20110224225A1,CCOC(=O)C(C(=O)OCC)C(C)Cc1ccncc1>>CC(Cc1ccncc1)C(=O)O,,Cl,,O=C([O-])O.[Na+],,test
US05109013,CNC1CCN(C)C1.Clc1nc2ccccc2[nH]1>>CN1CCC(N(C)c2nc3ccccc3[nH]2)C1,,[Na+],[OH-],,,test
US20020173646A1,COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1O.OCC1CCOC1>>COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCC1CCOC1,,CCOCC,ClCCl,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20080139631A1,CCCc1cc2c(C(F)(F)F)c(C#N)ccc2n1CC(=N)NO.CS(=O)(=O)c1ccc(Cl)c(C(=O)O)c1>>CCCc1cc2c(C(F)(F)F)c(C#N)ccc2n1Cc1noc(-c2cc(S(C)(=O)=O)ccc2Cl)n1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05391537,COC(=O)c1nc(N(C)C)ccc1O.COc1cc(OC)nc(S(C)(=O)=O)n1>>COC(=O)c1nc(N(C)C)ccc1Oc1nc(OC)cc(OC)n1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20050096350A1,COc1cc2c(Cl)c(C(=O)O)sc2cc1F.Nc1nnn[nH]1>>COc1cc2c(Cl)c(C(=O)Nc3nnn[nH]3)sc2cc1F,CN(C)C=O,ClCCl,O,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20100010053A1,CCOC(=O)CCc1cc2cc(Br)cc(F)c2[nH]1.N#C[Cu]>>CCOC(=O)CCc1cc2cc(C#N)cc(F)c2[nH]1,[Cu]I,CN(C)C=O,,,,test
US20160115170A1,CC(C)(C)OC(=O)N1[C@](C)(c2cc(Br)ccc2F)COS1(=O)=O.CCOC(=O)c1nc[nH]c1C(=O)OCC>>CCOC(=O)c1ncn(C[C@](C)(NC(=O)OC(C)(C)C)c2cc(Br)ccc2F)c1C(=O)OC,,CC#N,ClCCl,C1CCC2=NCCCN2CC1,,test
US20150166549A1,CC(N)c1oc(=O)c2ccccc2c1-c1ccccc1.Clc1ncnc2sccc12>>CC(Nc1ncnc2sccc12)c1oc(=O)c2ccccc2c1-c1ccccc1,,CC(C)(C)O,,CCN(CC)CC,Cl,test
US20030018046A1,NCc1ccc(CN(Cc2nc3ccccc3[nH]2)C2CCCc3cccnc32)cc1.O=Cc1ccccc1>>c1ccc(CNCc2ccc(CN(Cc3nc4ccccc4[nH]3)C3CCCc4cccnc43)cc2)cc1,,CO,,[BH4-].[Na+],,test
US20120214803A1,CC(C)c1ccc2cccnc2c1N.O=S(=O)(Cl)c1ccccc1>>CC(C)c1ccc2cccnc2c1NS(=O)(=O)c1ccccc1,CN(C)c1ccncc1,,,,,test
US05521147,C=C(C)Cc1c(Cl)ccc([N+](=O)[O-])c1O>>CC1(C)Cc2c(Cl)ccc([N+](=O)[O-])c2O1,,Cc1ccccc1C,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080167314A1,Cc1cccc(-c2nc3cccnn3c2-c2ccnc(N)c2)c1.O=C=Nc1ccccc1>>Cc1cccc(-c2nc3cccnn3c2-c2ccnc(NC(=O)Nc3ccccc3)c2)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20030045560A1,CN(Cc1ccc2c(Br)c(OCC#N)ccc2c1)C(=O)c1cn(C)c2ccccc12.[N-]=[N+]=[N-]>>CN(Cc1ccc2c(Br)c(OCc3nnn[nH]3)ccc2c1)C(=O)c1cn(C)c2ccccc12,,CN(C)C=O,,[Cl-].[NH4+],,test
US20070207175A1,CCCCCC(=O)Cl.CCCCOc1cc(CCC(=O)OC)ccc1-c1cccc(CNC)c1>>CCCCCC(=O)N(C)Cc1cccc(-c2ccc(CCC(=O)OC)cc2OCCCC)c1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,Cl,test
US20140081017A1,COC(=O)Cc1ccc(CCCCc2ccc(OC)cc2)cc1>>COC(=O)Cc1ccc(CCCCc2ccc(O)cc2)cc1,,ClCCl,,BrB(Br)Br,,test
US20040110767A1,Nc1ccc(OCCN2CCCC2)cc1.O=Cc1ccc(OC2CCCCO2)cc1>>C(=Nc1ccc(OCCN2CCCC2)cc1)c1ccc(OC2CCCCO2)cc1,,ClCCl,,O=S(=O)([O-])[O-].[Mg+2],,test
US20060106048A1,CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)OC)c(NCc3ccc(C#N)cc3)c1)=NC(C)(C)C2>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)O)c(NCc3ccc(C#N)cc3)c1)=NC(C)(C)C2,,CO,,Cl,[Na+].[OH-],test
US20110224204A1,O=S(=O)(Oc1c(Cl)cccc1-c1ccc(OCc2ccc3ccccc3n2)cc1)C(F)(F)F.OB(O)c1ccncc1>>Clc1cccc(-c2ccc(OCc3ccc4ccccc4n3)cc2)c1-c1ccncc1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20040014962A1,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)O.O=[N+]([O-])c1ccc(CO)cc1>>CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)OCc1ccc([N+](=O)[O-])cc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20150307489A1,CC(=O)OCC(=O)Cl.COc1ccc([C@H]2C[C@@H]2COc2nc(C)ncc2-c2ccc(C(N)=NO)cc2)nc1>>COc1ccc([C@H]2C[C@@H]2COc2nc(C)ncc2-c2ccc(-c3noc(COC(C)=O)n3)cc2)nc1,,c1ccncc1,,,,test
US20130245021A1,CC(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)CC1C.Cl>>CC(C)OC(=O)N1CCNCC1C.Cl,,CO,,,,test
US20110306612A1,COC(=O)c1cccc(C(=O)O)c1N.O=C(Cl)c1cccc(C(F)(F)F)c1>>COC(=O)c1cccc2c(=O)oc(-c3cccc(C(F)(F)F)c3)nc12,,c1ccncc1,,O=C([O-])O.[Na+],,test
US20020016347A1,Cc1ccccc1C(=O)c1ccc(N)cc1Cl.Clc1ccccn1>>Cc1ccccc1C(=O)c1ccc(Nc2ccccn2)cc1Cl,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20090275538A1,COC(=O)C1OC(Oc2cc(F)ccc2/C=C2\SC(N3CCCCN3)=NC2=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O>>O=C1N=C(N2CCCCN2)S/C1=C\c1ccc(F)cc1OC1OC(C(=O)O)C(O)C(O)C1O,,C1CCOC1,O,[Li+].[OH-],,test
US20130079412A1,CCOP(=O)(CC(=O)OC(C)(C)C)OCC.O=CC1CCC1>>CC(C)(C)OC(=O)/C=C/C1CCC1,,C1CCOC1,CN(C)C=O,O,[H-].[Na+],test
US20030232808A1,COC(=O)/C=C(/C)Br.c1ccc(CNCCNCc2ccccc2)cc1>>COC(=O)CC1CN(Cc2ccccc2)CCN1Cc1ccccc1,,CCN(CC)CC,Cc1ccccc1,,,test
US20150291617A1,Clc1ccc(-c2csc(N3C4CCC3COC4)n2)cc1.O=C1CCC(=O)N1Br>>Clc1ccc(-c2nc(N3C4CCC3COC4)sc2Br)cc1,,CN(C)C=O,,O,[Na+].[OH-],test
US03982006,CC1(C)CC(NC(=O)c2cc([N+](=O)[O-])cc([N+](=O)[O-])c2)CC(C)(C)N1>>CC1(C)CC(NC(=O)c2cc([N+](=O)[O-])cc([N+](=O)[O-])c2)CC(C)(C)N1,,O,,Cl,[Na+].[OH-],test
US20130035326A1,Cc1nc(N)ccc1Br.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1nc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)ccc1Br,,ClC(Cl)Cl,,,,test
US20080139484A1,CI.Cc1cccc2c1c(Cc1ccc(/C=C/CC(=O)O)cc1)cn2[C@@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>COC(=O)C/C=C/c1ccc(Cc2cn([C@@H]3O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)c3cccc(C)c23)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150191483A1,CC(C)(C)OC(=O)N1CC[C@](c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)(S(=O)(=O)c2ccc(F)cc2)C1.CCN(CC)S(F)(F)F>>CC(C)(C)OC(=O)N1CC[C@](c2ccc(C(F)(C(F)(F)F)C(F)(F)F)cc2)(S(=O)(=O)c2ccc(F)cc2)C1,,ClCCl,,,,test
US20150087639A1,O=[N+]([O-])c1ccc(NCCN2CCOCC2)c(F)c1>>Nc1ccc(NCCN2CCOCC2)c(F)c1,[Pd],C1CCOC1,,,,test
US06150373,CC(=O)NC(C)(C)Cc1ccc(Br)cc1.O=[N+]([O-])O>>CC(=O)NC(C)(C)Cc1ccc(Br)c([N+](=O)[O-])c1,,O=S(=O)(O)O,,,,test
US05547606,CCC[Mg]Cl.Fc1ccc([C@@H]2CC[C@@H](CCC3CC[SiH](Cl)CC3)CC2)cc1F>>CCC[Si@@H]1CC[C@@H](CC[C@@H]2CC[C@@H](c3ccc(F)c(F)c3)CC2)CC1,,C1CCOC1,,,,test
US20110294796A1,Brc1ccc(OCCN2CCCC2)cc1.Cc1cc(Br)cc2nnc(N)nc12.Cc1ccccc1.c1ccc(P(c2ccccc2)c2ccc3ccccc3c2-c2c(P(c3ccccc3)c3ccccc3)ccc3ccccc23)cc1>>Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(OCCN4CCCC4)cc3)nnc2c1,,Cc1ccccc1,,,,test
US06603020B1,CCCCS.N#Cc1ccc(Cl)cc1>>CCCCSc1ccc(C#N)cc1,,CC(=O)N(C)C,,O,O=C([O-])[O-].[K+].[K+],test
US20080004285A1,Nc1nc2ccc(Cl)nc2c(=O)[nH]1.OB(O)c1ccc(F)cc1>>Nc1nc2ccc(-c3ccc(F)cc3)nc2c(=O)[nH]1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US04482556,CC(C)(C)N.COc1cc2c(cc1OC)-c1cc(Cl)nc(=O)n1CC2>>COc1cc2c(cc1OC)-c1cc(NC(C)(C)C)nc(=O)n1CC2.Cl,,ClC(Cl)Cl,,,,test
US20130115190A1,CCI.COc1ccc2c(Cl)ncc(O)c2c1>>CCOc1cnc(Cl)c2ccc(OC)cc12,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090134780A1,Brc1ccc(Br)nc1.OB(O)c1cccnc1>>Brc1ccc(-c2cccnc2)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,O,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20110201777A1,CC(C)(C)OC(=O)n1c(=O)[nH]c2c(-c3ccc(-c4scc5c4[nH]c(=O)n5C(=O)OC(C)(C)C)cc3)scc21>>O=c1[nH]c2csc(-c3ccc(-c4scc5[nH]c(=O)[nH]c45)cc3)c2[nH]1,,CCOC(C)=O,,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],test
US20090286813A1,COc1cccc(-n2c(N)c(N)c(=O)[nH]c2=S)c1.N=CN>>COc1ccccc1-n1c(=S)[nH]c(=O)c2[nH]cnc21,,CS(C)=O,,CC(=O)O,,test
US20140296136A1,CN1CCC(O)CC1.COC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C1(C)CCCCC1)NC(=O)O[C@@H]1C[C@H]1CCCCCc1c(nc3ccccc3c1O)O2>>COC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C1(C)CCCCC1)NC(=O)O[C@@H]1C[C@H]1CCCCCc1c(nc3ccccc3c1OC1CCN(C)CC1)O2,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100056502A1,C[S+](C)(C)=O.O=C1CCn2c(=O)ccc3cccc1c32>>O=c1ccc2cccc3c2n1CCC31CO1,,CS(C)=O,,[H-].[Na+],,test
US20080176829A1,CC(C)(C)OC(=O)N1CCOc2ccc3[nH]ccc3c2C1.O=S(=O)(Cl)c1ccc2ccccc2c1>>O=S(=O)(c1ccc2ccccc2c1)n1ccc2c3c(ccc21)OCCNC3,,CO,N,CN(C)C=O,[H-].[Na+],test
US20020010371A1,N#CC1(CC(=O)O)C=CCC=C1>>NCC1(CC(=O)O)CCCCC1,[Pd],CO,,[NH4+].[OH-],,test
US05545651,CCCc1nc(CC)c(C(C)=O)n1Cc1ccc(I)cc1F.ICc1ccccc1Oc1ccccc1>>CCCc1nc(CC)c(C(=O)CCc2ccccc2Oc2ccccc2)n1Cc1ccc(I)cc1F,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US04839379,C=[N+]=[N-].Nc1ccc(C23CC2C(=O)NC3=O)cc1>>CN1C(=O)C2CC2(c2ccc(N)cc2)C1=O,,CO,,,,test
US20080188473A1,CCOC(=O)c1c(N)c2cc(-c3ccc(C(C)(C)C)cc3)ccc2n1-c1ccc(OC(C)C)cc1.CI>>CCOC(=O)c1c(NC)c2cc(-c3ccc(C(C)(C)C)cc3)ccc2n1-c1ccc(OC(C)C)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US05093335,CC(C)(C)Nc1nc(C#N)c(C#N)nc1Cl.CN>>CNc1nc(C#N)c(C#N)nc1NC(C)(C)C,,C1CCOC1,,O,,test
US05849930,CCN1CC(N)CN1CC.O=C(O)c1ccc(O)cc1O>>CCN1CC(NC(=O)c2ccc(O)cc2O)CN1CC,,ClC(Cl)Cl,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US07071175B1,C=C(CBr)C(=O)OCC.CC(C)(C)OC(=O)N1CCNCC1>>C=C(CN1CCN(C(=O)OC(C)(C)C)CC1)C(=O)OCC,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20110190395A1,CC/C=C\C/C=C\C/C=C\C/C=C\CCSC(C)=O>>CC/C=C\C/C=C\C/C=C\C/C=C\CCS,,CCOCC,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20130137661A1,BrCCc1ccccc1.Cc1c(N2CCNCC2)c(=O)n(C[C@H](NC(=O)OC(C)(C)C)c2ccccc2)c(=O)n1Cc1c(F)cccc1F>>Cc1c(N2CCN(CCc3ccccc3)CC2)c(=O)n(C[C@H](NC(=O)OC(C)(C)C)c2ccccc2)c(=O)n1Cc1c(F)cccc1F,,CN(C)C=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20110172230A1,N#Cc1ccc(NC(=O)N2CCC(Oc3ccc(OCc4cccc(F)c4)cc3)CC2)cn1.OO>>NC(=O)c1ccc(NC(=O)N2CCC(Oc3ccc(OCc4cccc(F)c4)cc3)CC2)cn1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130129753A1,CC(C)(C)OC(=O)N1CCCC[C@@]1(C)C(=O)O.CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC)OC)N(C)C(=O)[C@@H](N)C(C)C>>CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC)OC)N(C)C(=O)[C@@H](NC(=O)[C@]1(C)CCCCN1C(=O)OC(C)(C)C)C(C)C,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130178478A1,COC(=O)c1nnc(Cl)cc1Nc1cccc(C(C)C)n1.N>>CC(C)c1cccc(Nc2cc(Cl)nnc2C(N)=O)n1,,CO,,,,test
US06207675B1,COC(=O)CCS.NC(=O)c1c(Cl)c(-c2cccnc2)n2c1C=C(Cl)CC2>>NC(=O)c1c(Cl)c(-c2cccnc2)n2c1C=C(S)CC2,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20040053979A1,CO/C(=C\c1ccc2c(ccn2CCc2nc(-c3ccccc3)oc2C)c1)C(=O)O>>COC(Cc1ccc2c(ccn2CCc2nc(-c3ccccc3)oc2C)c1)C(=O)O,[Pd],CO,ClCCl,[H][H],,test
US20110230458A1,CCCCc1nnc(OC[C@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2OC)cc1-c1ccc(OC2CCCCC2)cc1.Cl.ClCCl>>CCCCc1nnc(OC[C@H]2CCNC[C@H]2OC)cc1-c1ccc(OC2CCCCC2)cc1.Cl.Cl,,C1COCCO1,ClCCl,,,test
US04804400,CC1=C(C)C(=O)OC1=O.Nc1ccc(Cl)cc1F>>CC1=C(C)C(=O)N(c2ccc(Cl)cc2F)C1=O,CN(C)c1ccncc1,Cc1ccccc1C,,O,,test
US20160272602A1,CS(=O)(=O)N[C@@H]1CCN(c2cc(C(F)(F)F)ccc2CN2CCNCC2)C1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OC(C(F)(F)F)C(F)(F)F>>CS(=O)(=O)N[C@@H]1CCN(c2cc(C(F)(F)F)ccc2CN2CCN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC2)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110046171A1,C1CCC2(C1)CN=NC2.CCNC(=N)SC>>CCNC(=N)N1CC2(C=N1)CCCC2,,c1ccncc1,,I,,test
US20060106048A1,CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccccc1)=NC(C)(CBr)C2.N#C[O-]>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccccc1)=NC(C)(CC#N)C2,,CS(C)=O,,O,,test
US20100120761A1,CC(=O)O.Nc1cccc(Nc2ncc(-c3ccc(F)cc3)cc2[N+](=O)[O-])c1>>Nc1cccc(-n2cnc3cc(-c4ccc(F)cc4)cnc32)c1,[Zn],,,,,test
US05998438,C1=COCCC1.CCCC[Sn](Cl)(CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)C1CCC=CO1,,C1CCOC1,O,[Li]C(C)(C)C,,test
US20040162352A1,CC(C)(C)OC(=O)C(C)(C)Br.CN(C)C(=O)Sc1ccc2c(c1)CC(N)C2>>CC(C)(C)OC(=O)C(C)(C)Sc1ccc2c(c1)CC(N)C2,,CO,,[K+].[OH-],,test
US20100056576A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1CC(c2ccncc2[N+](=O)[O-])=CC(NC(=O)OC(C)(C)C)C1OS(C)(=O)=O>>CC1CC(c2ccncc2[N+](=O)[O-])=CC2C1OC(=O)N2C(=O)OC(C)(C)C,,c1ccncc1,,CCN(CC)CC,,test
US20090082203A1,CC(C)=O.OCC(O)COc1ccc(Br)cc1>>CC1(C)OCC(COc2ccc(Br)cc2)O1,,CC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04137414,Cl.N#CCc1c(-c2ccccc2)sc2ccc(Cl)cc12>>Cl.NCCc1c(-c2ccccc2)sc2ccc(Cl)cc12,,CC(C)O,,[BH4-].[Na+],,test
US20020086879A1,COC(=O)c1cc(Cl)c(NC(C)=O)c2c1OCO2>>Nc1c(Cl)cc(C(=O)O)c2c1OCO2,,O,,Cl,[K+].[OH-],test
US20050032786A1,BrCCCc1ccccc1.O=c1nc(-c2ccccn2)sc2ccc(O)cc12>>O=c1nc(-c2ccccn2)sc2ccc(OCCCc3ccccc3)cc12,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05344845,CCOC(=O)CBr.COc1cc(C=CC(=O)N[C@@H]2CC[C@@H](C)CC2)ccc1O>>CCOC(=O)COc1ccc(C=CC(=O)N[C@@H]2CC[C@@H](C)CC2)cc1OC,,CC(=O)CC(C)C,,CO,O=C([O-])[O-].[K+].[K+],test
US20100063067A1,CC(=O)OC(C)=O.COc1cc(N2CCC(C(N)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)ccc1Cl>>COc1cc(N2CCC(C(Cn3nc(C(F)(F)F)c(Cl)c3C)NC(C)=O)CC2)ccc1Cl,CN(C)c1ccncc1,ClCCl,,,,test
US20120238587A1,CC1(C)OB(c2cncc(NS(=O)(=O)c3ccccc3)c2)OC1(C)C.Clc1ccc2ncnc(OC3CCOCC3)c2n1>>O=S(=O)(Nc1cncc(-c2ccc3ncnc(OC4CCOCC4)c3n2)c1)c1ccccc1,,C1COCCO1,,O=C([O-])O.[Na+],,test
US05686421,CCOC(=O)CN=C=O.N=C(NCCC[C@H](N)C(=O)O)N[N+](=O)[O-]>>N=C(NCCC[C@@H]1NC(=O)N(CC(=O)O)C1=O)N[N+](=O)[O-],,O,,Cl,O=C([O-])O.[Na+],test
US20150353493A1,COC=CC(C)=O.NCc1ccccc1>>CC(=O)C=CNCc1ccccc1,,ClC(Cl)Cl,,,,test
US20030144263A1,O=C(CCc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)N1CCN(c2ccc(N3C[C@H](COc4ccon4)OC3=O)cc2F)CC1>>O=C(CCc1c[nH]cn1)N1CCN(c2ccc(N3C[C@H](COc4ccon4)OC3=O)cc2F)CC1,,CCO,CO,CCN(CC)CC,Cl,test
US20120225866A1,CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(CNCc3ccncc3)ccc21.Cc1cc2c(=O)n(CC(O)O)ccc2o1>>CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(CN(CCn3ccc4oc(C)cc4c3=O)Cc3ccncc3)ccc21,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20070060754A1,CCCn1c(COCC)nc2c(N)nc3ccc(O)cc3c21.O=C(CBr)N1CCOCC1>>CCCn1c(COCC)nc2c(N)nc3ccc(OCC(=O)N4CCOCC4)cc3c21,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US04110447,BrCCCCCBr.CC(CCN)c1ccccc1-c1ccccc1>>CC(CCN1CCCCC1)c1ccccc1-c1ccccc1,,CCCCO,,O=C([O-])[O-].[K+].[K+],,test
US20130102776A1,COc1ccc2c(c1C1C=CCCN1C(=O)[O-])OC(=Cc1n[nH]c3ccccc13)C2=O>>COc1ccc2c(c1C1=CCNCC1)O/C(=C\c1n[nH]c3ccccc13)C2=O,,ClCCl,,C1COCCO1,Cl,test
US20080242685A1,CC(C)(C)OC(=O)N1CCC(c2n[nH]c3c(C(N)=O)nc(-c4ccccc4)cc23)CC1>>NC(=O)c1nc(-c2ccccc2)cc2c(C3CCNCC3)n[nH]c12,,CO,,Cl,,test
US20140243302A1,CON.COc1ccc2ncc(F)c(CCC34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2n1>>CON=C1COc2ccc(CNC34CCC(CCc5c(F)cnc6ccc(OC)nc56)(CC3)OC4)nc2N1,,c1ccncc1,,Cl,,test
US20110237573A1,O=[N+]([O-])c1ccc(-c2cccc(F)c2)nc1>>Nc1ccc(-c2cccc(F)c2)nc1,[Pd],CO,,[H][H],,test
US04556711,Clc1cnccn1.O=C(OCc1ccccc1)N(O)c1ccccc1>>O=C(Nc1ccc(-c2c[nH]c(=O)cn2)cc1)OCc1ccccc1,,CC(=O)O,,[K+].[OH-],,test
US20120202988A1,CC(CO)(CO)C(=O)O.COC(OC)(c1ccccc1)c1ccccc1>>CC1(C(=O)O)COC(c2ccccc2)(c2ccccc2)OC1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100222321A1,COc1ccc(C=O)cn1>>O=Cc1ccc(O)nc1,,Cl,,,,test
US20020037891A1,CCOC(=O)c1cn(-c2ccc(F)cc2F)c2nc3c(F)c(F)c(F)cc3cc2c1=O.Fc1ccc(N2CCNCC2)cc1>>CCOC(=O)c1cn(-c2ccc(F)cc2F)c2nc3c(F)c(N4CCN(c5ccc(F)cc5)CC4)c(F)cc3cc2c1=O,,CS(C)=O,,O,,test
US05493053,CC(C)(C)OC(=O)NCCCCCN(OCc1ccccc1)C(=O)CCC(=O)NCCCCCNOCc1ccccc1.O=C1CCC(=O)O1>>CC(C)(C)OC(=O)NCCCCCN(OCc1ccccc1)C(=O)CCC(=O)NCCCCCN(OCc1ccccc1)C(=O)CCC(=O)O,,c1ccncc1,,,,test
US20090036453A1,CC(C)[N+](=O)[O-].C[Si](C)(C)CCOCn1c(Br)c(CBr)c2c(=O)[nH]ncc21>>C[Si](C)(C)CCOCn1c(Br)c(C=O)c2c(=O)[nH]ncc21,,CCO,,C,C[O-].[Na+],test
US20160039811A1,COc1ccn(C(C)C2(C)CC2)c(=O)c1C#N.O=C1CCC(=O)N1Br>>COc1c(Br)cn(C(C)C2(C)CC2)c(=O)c1C#N,,O,,CN(C)C=O,,test
US20080070960A1,COc1cc(OC)c(-c2noc3ccccc23)cc1Br>>Oc1cc(O)c(-c2noc3ccccc23)cc1Br,,ClCCl,,BrB(Br)Br,,test
US20070045613A1,CCCCCCCCc1ccc(C#C[Si](C)(C)C)s1>>C#Cc1ccc(CCCCCCCC)s1,,CO,O,C1CCOC1,O=C([O-])[O-].[K+].[K+],test
US20130130396A1,O=C(O)CC(O)(CC(=O)O)C(=O)O.O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Na+].[Na+].[Na+]>>O=C(O)CC(O)(CC(=O)O)C(=O)O.O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Na+].[Na+].[Na+],,O,,,,test
US05726325,CC(O)(C(=O)O)C(F)(F)F.Nc1cccc2c1C(=O)c1sccc1CO2>>CC(O)(C(=O)Nc1cccc2c1C(=O)c1sccc1CO2)C(F)(F)F,,CC(=O)N(C)C,CCOC(C)=O,O=S(Cl)Cl,,test
US20080255092A1,CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(CSc3ccc(-c4csc(NCC5CC5)n4)cn3)c2CC1>>Clc1ccc2c(c1CSc1ccc(-c3csc(NCC4CC4)n3)cn1)CCNCC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130237535A1,COC(=O)C1(NC(=O)OC(C)(C)C)CCNCC1.O=S(=O)(Cl)c1ccc(Br)cc1>>COC(=O)C1(NC(=O)OC(C)(C)C)CCN(S(=O)(=O)c2ccc(Br)cc2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090233918A1,C[C@@H]1CNCCN1c1nc(-c2ccncn2)cc(=O)n1C.Cc1nc(-c2ccc(CBr)cc2)no1>>Cc1nc(-c2ccc(CN3CCN(c4nc(-c5ccncn5)cc(=O)n4C)[C@H](C)C3)cc2)no1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120197014A1,CCCCCCCCn1cc(CN)c2cc(-c3cccc(C)c3)ccc21.CS(=O)(=O)Cl>>CCCCCCCCn1cc(CNS(C)(=O)=O)c2cc(-c3cccc(C)c3)ccc21,,C1CCOC1,,CCN(CC)CC,,test
US04876027,CCCCCCCCCCCCOc1ccc(C(=O)O)cc1.ClP(Cl)(Cl)(Cl)Cl>>CCCCCCCCCCCCOc1ccc(C(=O)Cl)cc1,,c1ccccc1,,,,test
US04929618,NC(=O)CCCN1CCC(OC(c2ccc(Cl)cc2)c2ccccn2)CC1.O=C(O)/C=C\C(=O)O>>NC(=O)CCCN1CCC(OC(c2ccc(Cl)cc2)c2ccccn2)CC1.O=C(O)/C=C\C(=O)O,,CCO,,,,test
US20160122335A1,CC(C)(C)OC(=O)c1csc(-c2noc(C(C)(C)O)n2)n1>>CC(C)(O)c1nc(-c2nc(C(=O)O)cs2)no1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070254868A1,COc1ccc(CNc2ncc(-c3cccnc3)cc2-c2ncsc2-c2cccc(Cl)c2Cl)cc1>>Nc1ncc(-c2cccnc2)cc1-c1ncsc1-c1cccc(Cl)c1Cl,,O=C(O)C(F)(F)F,,,,test
US20080269193A1,N#Cc1c(F)cc(Br)cc1F.N[C@H]1CCOC1>>N#Cc1c(F)cc(Br)cc1N[C@H]1CCOC1,,CS(C)=O,,O,,test
US07285558B2,Cn1cc(C#N)cc1-c1c2c(=O)n(C)c(=O)n(CC3CC3)c2nn1Cc1ccnc2ccc(Cl)cc12.[N-]=[N+]=[N-]>>Cn1cc(-c2nnn[nH]2)cc1-c1c2c(=O)n(C)c(=O)n(CC3CC3)c2nn1Cc1ccnc2ccc(Cl)cc12,,CN(C)C=O,,[Cl-].[NH4+],,test
US06765089B1,CC(=O)OC(C)=O.O=C1CC(=O)c2ccccc21>>CC(=O)C1C(=O)c2ccccc2C1=O,CN(C)c1ccncc1,ClCCCl,,CCN(CC)CC,,test
US20020091261A1,CC(=O)Nc1ccc2c(Cc3ccncc3)nnc(Cl)c2c1.Nc1ccc(Cl)cc1>>CC(=O)Nc1ccc2c(Cc3ccncc3)nnc(Nc3ccc(Cl)cc3)c2c1.Cl,,CCCCO,,,,test
US05444082,CC(=O)OC1CCC2(CCC(C=O)CC2)CC1>>CC(=O)OC1CCC2(CCC(CO)CC2)CC1,,CO,,[BH4-].[Na+],[Cl-].[NH4+],test
US20110237584A1,CC[Si](CC)(CC)OC(C1CCNCC1)C(F)(F)F.O=C(Cl)C1CC1>>CC[Si](CC)(CC)OC(C1CCN(C(=O)C2CC2)CC1)C(F)(F)F,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20080255092A1,CC(C)(C)OC(=O)N1CCc2ccc(Cl)c(CNc3ccc(C(=O)NC4CCCCCC4)cc3)c2CC1>>O=C(NC1CCCCCC1)c1ccc(NCc2c(Cl)ccc3c2CCNCC3)cc1,,CCOC(C)=O,CO,Cl,,test
US20030018194A1,CC1(C2(C=O)CC2)OCCO1.COC(=O)CP(=O)(OC)OC>>COC(=O)/C=C/C1(C2(C)OCCO2)CC1,,C1CCOC1,,[H-].[Na+],,test
US20100003250A1,CN(C)CCn1ccc2c(N3CCOCC3)nc(Cl)nc21.OB(O)c1cccc(O)c1>>CN(C)CCn1ccc2c(N3CCOCC3)nc(-c3cccc(O)c3)nc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20040186060A1,BrCCc1ccccc1.COC(=O)C(CCSC)N=Cc1ccc(Cl)cc1.Cl>>COC(=O)C(N)(CCSC)CCc1ccccc1.Cl,,CN(C)C=O,,[H-].[Na+],,test
US20070244159A1,Fc1cc2c(cc1CCl)OCO2.[C-]#N>>N#CCc1cc2c(cc1F)OCO2,,CS(C)=O,,O,,test
US20100099681A1,CC1(C)OB(c2cc(F)c3nccnc3c2)OC1(C)C.COC(=O)c1ccccc1Nc1c(Br)c(C)nn1-c1ccc(F)cc1C>>COC(=O)c1ccccc1Nc1c(-c2cc(F)c3nccnc3c2)c(C)nn1-c1ccc(F)cc1C,,C1COCCO1,O,C1CCC(P(C2CCCCC2)C2CCCCC2)CC1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20020193385A1,CCOC(CBr)OCC.Nc1nccc(C(F)(F)F)n1>>FC(F)(F)c1ccn2ccnc2n1,,CCO,,Br,,test
US20060247238A1,CC(C)(C)OC(=O)N1C[C@H](N=[N+]=[N-])[C@@H](O)C1>>CC(C)(C)OC(=O)N1C[C@H](N)[C@@H](O)C1,O=[Pt]=O,CO,,,,test
US20070249593A1,COc1ccc(CN)cc1.O=C1CC(c2ccc([N+](=O)[O-])cc2)CC(=O)O1>>COc1ccc(CN2C(=O)CC(c3ccc([N+](=O)[O-])cc3)CC2=O)cc1,,C1CCOC1,,,,test
US20080188471A1,CC(C)(C)OC(=O)OC(=O)[O-].OC1=CC=C(O)N(O)C1O>>CC(C)(C)OC(=O)N1CC(O)=CC=C1O,,C1CCOC1,O,CCOC(C)=O,,test
US04263319,CCOC(=O)C(Cc1ccccc1-c1ccccc1)C(=O)OCC>>O=C(O)C(Cc1ccccc1-c1ccccc1)C(=O)O,,CCO,O,[K+].[OH-],,test
US20080045521A1,CN(C(=O)OC(C)(C)C)c1cccc(CCOc2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)OC(C)(C)C)cn2)n1>>CNc1cccc(CCOc2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cn2)n1,,O=C(O)C(F)(F)F,,,,test
US20150361070A1,CC[C@H](N)c1nc2cccc(Cl)c2c(=O)n1-c1cc[nH]n1.N#Cc1c(N)nc(N)nc1Cl>>CC[C@H](Nc1nc(N)nc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1cc[nH]n1,,CC(C)O,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20140142325A1,B.Cc1cc(Br)c(Br)cc1C.c1ccc(Pc2ccccc2)cc1>>B.Cc1cc(Br)c(P(c2ccccc2)c2ccccc2)cc1C,,C1CCOC1,,[Li]CCCC,,test
US20080103123A1,CC(C)(C)OC(=O)N1CCC(N)CC1.OCc1ccc(Br)cn1>>CC(C)(C)OC(=O)N1CCC(NCc2ccc(Br)cn2)CC1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,O=S(Cl)Cl,test
US20020103141A1,CCOC(=O)C1=Cc2cc(Cl)c(C)c(Cl)c2OC1C(F)(F)F>>Cc1c(Cl)cc2c(c1Cl)OC(C(F)(F)F)C(C(=O)O)=C2,,C1CCOC1,CCO,[Na+].[OH-],,test
US20050090498A1,O=C1Nc2cc(C(=O)OCc3ccccc3)ccc2C1=C1C=Cc2ccccc2N1>>O=C1Nc2cc(C(=O)O)ccc2C1=C1C=Cc2ccccc2N1,[Pd],CN(C)C=O,,,,test
US20140057291A1,Brc1c(Br)c(Br)c2[nH]cnc2c1Br.COC(=O)CCCCCCCBr>>O=C(O)CCCCCCCn1cnc2c(Br)c(Br)c(Br)c(Br)c21,,CN(C)C=O,,[H-].[Na+],,test
US20070254873A1,N.O=C(O)c1cc(Br)cc2cc[nH]c12>>NC(=O)c1cc(Br)cc2cc[nH]c12,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US04450149,C=CCCCO.O=C(Cl)c1ccccc1>>C=CCCCOCc1ccccc1,,c1ccncc1,,O,,test
US20160068496A1,CCCS(=O)(=O)Nc1cccc(B2OC(C)(C)C(C)(C)O2)c1F.Clc1ccc2nc(Cl)nc(N3CCOCC3)c2n1>>CCCS(=O)(=O)Nc1cccc(-c2ccc3nc(Cl)nc(N4CCOCC4)c3n2)c1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20160016951A1,Cc1ncc(-c2ccc(-c3cnn(C)c3)cc2)c2[nH]c(=O)ccc12.O=P(Cl)(Cl)Cl>>Cc1ncc(-c2ccc(-c3cnn(C)c3)cc2)c2nc(Cl)ccc12,CN(C)C=O,,,,,test
US04075165,CC(=O)OC(C)=O.CCC1(C)CC(OC(=O)c2ccccc2)C(C)C(C)(CC)N1CCO>>CCC1(C)CC(OC(=O)c2ccccc2)C(C)C(C)(CC)N1CCOC(C)=O,,CN(C)C=O,,CCN(CC)CC,,test
US20100249163A1,COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(O)c2ccc(F)c(F)c2)C2CC2)c(Cl)c[n+]1[O-]>>COCCCc1cc(CN(C(=O)C2CNCCC2(O)c2ccc(F)c(F)c2)C2CC2)c(Cl)c[n+]1[O-],,ClCCl,,Cl,,test
US20070155839A1,Cc1noc(C)c1B(O)O.Oc1ccc(C(=C2CCCCCC2)c2ccc(Br)cc2)cc1>>Cc1noc(C)c1-c1ccc(C(=C2CCCCCC2)c2ccc(O)cc2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,O,O=C([O-])[O-].[Na+].[Na+],,test
US06350749B1,CCOC(=O)c1coc2c1C(=O)CC(c1ccccc1)C2.Cl.N=C(N)NN>>CCOC(=O)c1coc2c1/C(=N/NC(=N)N)CC(c1ccccc1)C2.Cl,,CCO,,Cl,,test
US20150105369A1,COc1ccc(Br)cn1.Cc1cc(C(=O)c2ccc3nc(Cl)c(-c4ccccc4)c(Cl)c3c2)on1>>COc1ccc(C(O)(c2ccc3nc(Cl)c(-c4ccccc4)c(Cl)c3c2)c2cc(C)no2)cn1,,C1CCOC1,,[Li]CCCC,,test
US20150284362A1,CC(NC(=O)OC(C)(C)C)C(N)=O>>CC(CN)NC(=O)OC(C)(C)C,,C1CCOC1,,B,,test
US20110274638A1,CCOC(=O)C(NC(=O)OC(C)(C)C)C(=O)c1ccc(OC)cc1>>CCOC(=O)C(NC(=O)OC(C)(C)C)C(O)c1ccc(OC)cc1,,CCO,,[BH4-].[Na+],[Cl-].[NH4+],test
US20060287386A1,COC(=O)c1ccccc1SCl.Cc1cc2ccccc2s1>>COC(=O)c1ccccc1Sc1c(C)sc2ccccc12,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20030092712A1,COC(=O)c1cc(Br)c2c(c1)N(c1c(Cl)cccc1Cl)C(=O)OC2.OB(O)c1ccccc1Cl>>COC(=O)c1cc(-c2ccccc2Cl)c2c(c1)N(c1c(Cl)cccc1Cl)C(=O)OC2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US04317915,CCCC1SCC(C(=O)OC)C1=O.NO>>CCCC1SCC(C(=O)OC)C1=NO,,c1ccncc1,,Cl,,test
US20090264406A1,C1CCNC1.OCCn1cc(-c2ccc3ncc(Cc4ccc5ncccc5c4)n3n2)cn1>>c1cnc2ccc(Cc3cnc4ccc(-c5cnn(CCN6CCCC6)c5)nn34)cc2c1,,C1CCOC1,ClCCl,CCN(CC)CC,CS(=O)(=O)Cl,test
US20110053909A1,Br.OCCc1cccc(CCO)c1>>OCCc1cccc(CCBr)c1,,Cc1ccccc1,,,,test
US20050038041A1,COc1nc(C)nc(C(F)(F)F)c1C#C[Si](C)(C)C>>C#Cc1c(OC)nc(C)nc1C(F)(F)F,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20110152290A1,CC(=O)OC(C)=O.OCCc1cccc(CCO)c1>>CC(=O)OCCc1cccc(CCO)c1,,CC#N,,,,test
US06800785B1,C=CCCBr.CN(C)C=O.COc1ccc2c(c1)CCC2=O.ClCCl>>C=CCCC1(CCC=C)Cc2cc(OC)ccc2C1=O,,CN(C)C=O,ClCCl,[H-].[Na+],,test
US20100093694A1,CC(C)(N)c1ccccc1.CCOC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3cccc(C(=O)O)c3)cc12>>CCOC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3cccc(C(=O)NC(C)(C)c4ccccc4)c3)cc12,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120165339A1,CC#CC(=O)OCC.CCNN>>CCn1nc(C)cc1O,,ClCCl,,,,test
US05348944,CCOC(=O)[C@@H]1CC2CCCCC2N1C(=O)[C@H](C)NC(=O)OCc1ccccc1>>C[C@H](NC(=O)OCc1ccccc1)C(=O)N1C2CCCCC2C[C@H]1C(=O)O,,CO,,[Na+].[OH-],,test
US04210648,C1COCCO1.C=CC(=O)N1c2ccccc2C(=O)Nc2cccnc21.O=C1Nc2cccnc2N(C(=O)CCCl)c2ccccc21>>O=C1Nc2cccnc2N(C(=O)CCCCCCl)c2ccccc21,,C1COCCO1,,CC#N,CCN(CC)CC,test
US20040220185A1,C#C[Si](C)(C)C.CC(C)(C)OC(=O)N1CCN(c2ccc(I)cn2)CC1>>CC(C)(C)OC(=O)N1CCN(c2ccc(C#C[Si](C)(C)C)cn2)CC1,,CC(=O)N(C)C,,CCN(CC)CC,,test
US20080085890A1,C1CCOC1.CN(C)C=Cc1ccn(-c2ccoc2)c(=O)c1>>O=Cc1ccn(-c2ccoc2)c(=O)c1,,C1CCOC1,,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20100298290A1,Cc1ncnc(N2CCOc3ccc(-c4cnc(N)c([N+](=O)[O-])c4)cc3C2)c1Cc1ccc(F)cc1>>Cc1ncnc(N2CCOc3ccc(-c4cnc(N)c(N)c4)cc3C2)c1Cc1ccc(F)cc1,,CC(=O)O,,Cl[Sn]Cl,,test
US20090247559A1,CN1CCNCC1.O=c1[nH]c(CCl)nc2c1oc1ccc(C3CC3)cc12>>CN1CCN(Cc2nc3c(oc4ccc(C5CC5)cc43)c(=O)[nH]2)CC1,,CCO,,,,test
US20090270443A1,COc1ccc(CN)cc1.Cc1nc(Cl)c2ncn(N(C)C)c2c1C>>COc1ccc(CNc2nc(C)c(C)c3c2ncn3N(C)C)cc1,,OCC(F)(F)F,,Cl,c1ccncc1,test
US20130116204A1,CC(=O)OC1C(OC(=N)C(Cl)(Cl)Cl)OC(C(=O)OCc2ccccc2)C(OC(C)=O)C1OC(C)=O.CCOc1cc([C@@H](CS(C)(=O)=O)N2Cc3cccc(NC(=O)C4CC4)c3C2=O)ccc1O>>CCOc1cc([C@@H](CS(C)(=O)=O)N2Cc3cccc(NC(=O)C4CC4)c3C2=O)ccc1O[C@@H]1O[C@H](C(=O)OCc2ccccc2)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O,,CCOC(C)=O,ClCCl,CCOCC,FB(F)F,test
US20020103229A1,N#Cc1ccc2[nH]nc(-c3ccc4c(c3)CCO4)c2c1.OO>>NC(=O)c1ccc2[nH]nc(-c3ccc4c(c3)CCO4)c2c1,,CCO,O,Cl,[Na+].[OH-],test
US20090054681A1,CC(=O)Oc1c(F)cccc1C1CC1>>Oc1c(F)cccc1C1CC1,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20110306607A1,COC(=O)c1ccc(O)c(OC)c1.O=S(=O)(OCCOC(F)(F)F)C(F)(F)F>>COC(=O)c1ccc(OCCOC(F)(F)F)c(OC)c1,,CN(C)C=O,,[H-].[Na+],,test
US20150366977A1,CC(=O)N1CCc2cc(Br)ccc21.O=S(=O)(O)Cl>>CC(=O)N1CCc2cc(Br)c(S(=O)(=O)Cl)cc21,,CCOC(C)=O,,,,test
US20100324049A1,Brc1c[nH]c2cnccc12.COS(=O)(=O)OC>>Cn1cc(Br)c2ccncc21,,CN(C)C=O,,[H-].[Na+],,test
US20100249119A1,Nc1cccc(NC(=O)c2cccc(C(F)(F)F)c2)c1.O=CO>>O=CNc1cccc(NC(=O)c2cccc(C(F)(F)F)c2)c1,,C1CCOC1,,CC(=O)OC(C)=O,,test
US20160194358A1,CCCCc1ccc(-c2ccc(NC(=O)OC(C)(C)C)cn2)cc1>>CCCCc1ccc(-c2ccc(N)cn2)cc1,,CCOC(C)=O,Cl,,,test
US20130210824A1,N=C(N)NN=C(Cc1c(F)ccc(F)c1F)c1cc(Cl)ccc1Br>>N=C(N)n1nc(Cc2c(F)ccc(F)c2F)c2cc(Cl)ccc21,[Cu]I,CN1CCCC1=O,,N,,test
US20070054916A1,Brc1ccc2nc(I)ncc2c1.Nc1ccc(OCCCN2CCCCC2)cc1>>Brc1ccc2nc(Nc3ccc(OCCCN4CCCCC4)cc3)ncc2c1,,CC(C)O,,O=C(O)C(F)(F)F,,test
US20120225886A1,CC(C)(C)OC(=O)N1[C@H](Cc2ccc(C(=O)O)cc2)CC[C@@H]1[C@H](O[Si](C)(C)C(C)(C)C)c1ccccc1.NCCc1ccccn1>>CC(C)(C)OC(=O)N1[C@H](Cc2ccc(C(=O)NCCc3ccccn3)cc2)CC[C@@H]1[C@H](O[Si](C)(C)C(C)(C)C)c1ccccc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050288273A1,Cn1cc([N+](=O)[O-])cc([N+](=O)[O-])c1=O.O=C1CCCCCC1>>O=[N+]([O-])c1cnc2c(c1)CCCCC2,,CO,,N,,test
US20150368228A1,CC(C)(C)OC(=O)N1CC=C(c2c(Cl)cc(N)cc2C(F)(F)F)CC1.S=C(n1ccnc1)n1ccnc1>>CC(C)(C)OC(=O)N1CC=C(c2c(Cl)cc(N=C=S)cc2C(F)(F)F)CC1,,ClCCl,,,,test
US05852016,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].COc1nc2cc(Cl)c(Cl)c(N(CC#N)S(C)(=O)=O)c2nc1OC>>COc1nc2cc(Cl)c(Cl)c(N(Cc3nnn[nH]3)S(C)(=O)=O)c2nc1OC,,Cc1ccccc1,,,,test
US20130109685A1,N#CN.O=C(O)COc1ccc(Cl)cc1[C@@H]1c2ccccc2CCN1C(=O)OCc1ccccc1>>N#CNC(=O)COc1ccc(Cl)cc1[C@@H]1c2ccccc2CCN1C(=O)OCc1ccccc1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130190306A1,C1CNC1.O=Cc1ccc(C2Nc3cccc4c(=O)[nH]nc(c34)C2c2ccccc2)cc1>>O=c1[nH]nc2c3c(cccc13)NC(c1ccc(CN3CCC3)cc1)C2c1ccccc1,,CO,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04414226,CC(=O)OC(C)=O.COc1cc(C)cc2c(=O)oc3c(c12)C(=O)c1cccc(O)c1C3=O>>COc1cc(C)cc2c(=O)oc3c(c12)C(=O)c1cccc(OC(C)=O)c1C3=O,,c1ccncc1,,,,test
US20050020652A1,CCOC(=O)C(C)(Cc1cccc(OCCC2CN(Cc3ccc(C(F)(F)F)cc3)C(=O)N2C)c1)Oc1ccccc1>>CN1C(=O)N(Cc2ccc(C(F)(F)F)cc2)CC1CCOc1cccc(CC(C)(Oc2ccccc2)C(=O)O)c1,,CO,,Cl,[Na+].[OH-],test
US06806230B1,CC(C)C(Cl)c1cncnc1C(F)(F)F.NCCNc1ccccc1>>CC(C)C(NCCNc1ccccc1)c1cncnc1C(F)(F)F,,CC(C)O,,,,test
US20080004309A1,CCOC(=O)CNCc1ccc(OC)cc1OC.CCOC(=O)c1sc(-c2cccc(OC)c2)nc1CBr>>CCOC(=O)CN(Cc1ccc(OC)cc1OC)Cc1nc(-c2cccc(OC)c2)sc1C(=O)OCC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120028964A1,CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(NC(=O)c3ccc(OCC(F)(F)F)nc3)cc2)C1.Cl>>Cl.O=C(Nc1ccc([C@H]2CNCCO2)cc1)c1ccc(OCC(F)(F)F)nc1,,C1COCCO1,,,,test
US20040024010A1,CCOC(=O)CCc1c(C=O)[nH]c(C(=O)OCC)c1C.Cc1cccc2c1CC(=O)N2>>Cc1cccc2c1C(=Cc1[nH]c(C(=O)O)c(C)c1CCC(=O)O)C(=O)N2,C1CCNCC1,CCO,,[K+].[OH-],,test
US20140249143A1,FC(F)(F)c1nc(C(F)(F)F)nc(C(F)(F)F)n1.Nc1cccc(N)n1>>Nc1ccc2c(C(F)(F)F)nc(C(F)(F)F)nc2n1,,CC(=O)O,,,,test
US20090029903A1,CC1(C)OC(=O)c2ccc(N)cc2O1.O=C(Cl)CCC1CCCC1>>CC1(C)OC(=O)c2ccc(NC(=O)CCC3CCCC3)cc2O1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150158851A1,CCOC(=O)c1n[nH]c2c1CC1C(F)(F)C1(C)C2>>CC12Cc3[nH]nc(C(=O)O)c3CC1C2(F)F,,O,,CCO,[Na+].[OH-],test
US20120171703A1,COc1ccc(-c2cnc(N)c(Br)n2)cc1.Sc1ccccc1>>COc1ccc(-c2cnc(N)c(Sc3ccccc3)n2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04371708,CC(=O)C(C)(C)COS(=O)(=O)c1ccc(C)cc1.Oc1ccc(Cl)cc1>>CC(=O)C(C)(C)COc1ccc(Cl)cc1,,CO,,O,C[O-].[Na+],test
US08772533B1,C/C=C/C(=O)Cl.CC(C)C(C)O>>CC=CC(=O)OC(C)C(C)C,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US04954509,O=C(Cl)c1cccs1.Oc1cccc2c1CCNC2CN1CCCC1>>O=C(c1cccs1)N1CCc2c(O)cccc2C1CN1CCCC1,,ClC(Cl)Cl,,,,test
US04157347,C#CCN.CSC(=NC#N)SC>>C#CCN=C(NC#N)SC,,CC#N,,,,test
US20050165001A1,CC(C)(C)OC(=O)N1CCN(c2cccc(N)c2C#N)CC1.O=C(Cl)c1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCN(c2cccc(NC(=O)c3ccc(F)cc3)c2C#N)CC1,,C1CCOC1,,CCN(CC)CC,,test
US04894381,C=C(c1ccccc1O)n1ccnc1.CC(C)=C(C)CCl>>C=C(c1ccccc1OCC(C)=C(C)C)n1ccnc1,,CO,,[Na+].[OH-],,test
US04200748,Nc1cccc2nc3c(nc12)N1CCCCC1CO3.O=C(Cl)c1ccccc1>>O=C(Nc1cccc2nc3c(nc12)N1CCCCC1CO3)c1ccccc1,,ClCCl,,[Na+].[OH-],,test
US20110201629A1,COC(=O)[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](COS(=O)(=O)C(F)(F)F)CC1,,ClCCl,,c1ccncc1,,test
US20140206681A1,CCOC(=O)C=O.COC(=O)c1ccc(C)nc1>>CCOC(=O)/C=C/c1ccc(C(=O)OC)cn1,,CC(=O)OC(C)=O,,,,test
US20030199525A1,Nc1ccc(-c2coc3ncnc(N)c23)cc1.O=C(Cl)c1ccccc1>>Nc1ncnc2occ(-c3ccc(NC(=O)c4ccccc4)cc3)c12,,ClCCl,,c1ccncc1,,test
US20060154931A1,CC(=O)c1ccc(O)cc1.ClCc1ccc2ccccc2n1>>CC(=O)c1ccc(OCc2ccc3ccccc3n2)cc1,,CC(C)=O,CCOC(C)=O,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20100298320A1,CCOC(=O)c1cc(C(C)(C)C)n[nH]1.COCCl>>CCOC(=O)c1cc(C(C)(C)C)nn1COC,,ClCCl,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20140274930A1,CC1(C)OC[C@H]([C@H]2OC(O)[C@@]3(C)OC(C)(C)O[C@@H]23)O1>>C[C@@]1(O)C(O)O[C@H](CO)[C@@H](O)[C@@H]1O,,C1COCCO1,O,,,test
US20070225372A1,CN1CCN(C(=O)OCc2ccccc2)CC1=O.O=CC(Cc1ccccc1)N(Cc1ccccc1)Cc1ccccc1>>CN1CCN(C(=O)OCc2ccccc2)C(C(O)[C@H](Cc2ccccc2)N(Cc2ccccc2)Cc2ccccc2)C1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20040102435A1,COc1ccc(C(=O)Nc2ccc(Br)cc2)cc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COc1ccc(C(=S)Nc2ccc(Br)cc2)cc1,,Clc1ccccc1,,,,test
US20100143505A1,COc1cc2c(cc1OC)C(=O)C(CC1CCN(C(=O)OC(C)(C)C)CC1)C2>>COc1cc2c(cc1OC)C(=O)C(CC1CCNCC1)C2,,CCOC(C)=O,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20150366851A1,CC(=O)O.CCCC(=O)CC(=O)N[C@@H](C)CC1(C)OCCCO1>>CCCCCCCC(=O)CC(=O)N[C@@H](C)CC(C)=O,,CC(=O)O,,,,test
US20130072467A1,CCOCCN.O=C1NC(=S)CS1>>CCOCCNC1=NC(=O)SC1,,CCO,,,,test
US20060135578A1,COC(=O)c1cc(-c2nc(CCl)c(C)o2)ccc1C.COc1cc(C=O)ccc1O>>COC(=O)c1cc(-c2nc(COc3ccc(C=O)cc3OC)c(C)o2)ccc1C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150246897A1,Clc1cc(N2CCOCC2)nc(N2CCOCC2)n1.Nc1cc(C(F)(F)F)c(B2OCCNCCO2)cn1>>Nc1cc(C(F)(F)F)c(-c2cc(N3CCOCC3)nc(N3CCOCC3)n2)cn1,[Pd],,,,,test
US05652271,CN(C)CCCSCC(=O)C1(c2ccc(Cl)c(Cl)c2)CCC1.O=C(O)/C=C/C(=O)O>>CN(C)CCCSCC(=O)C1(c2ccc(Cl)c(Cl)c2)CCC1.O=C(O)/C=C/C(=O)O,,CCO,CCOCC,,,test
US03980089,COC1CCC(OC)O1.Nc1cnccn1>>c1ccn(-c2cnccn2)c1,,CC(=O)O,,[Na+].[OH-],,test
US20090325989A1,CC(=O)NN(Cc1ccccc1Br)c1nc(C)cc(Nc2ccc(Cl)cc2)n1>>Cc1cc(Nc2ccc(Cl)cc2)nc(N(N)Cc2ccccc2Br)n1,,Cl,O,O=C([O-])O.[Na+],,test
US05889026,OC1(Cc2ccccc2)CCNCC1.c1ccc(COc2ccc(OC[C@H]3CO3)cc2)cc1>>O[C@@H](COc1ccc(OCc2ccccc2)cc1)CN1CCC(O)(Cc2ccccc2)CC1,,CCO,,,,test
US20100087427A1,C#CC(=O)OCC.CC(C)c1cccc(O)c1>>CCOC(=O)/C=C/Oc1cccc(C(C)C)c1,,C1CCOC1,,CN1CCOCC1,,test
US20150322043A1,CCOC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1.NCCO>>O=C(NCCO)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1,,CO,,CCN(C(C)C)C(C)C,,test
US20110263594A1,Fc1cccc(-c2ccc3nncn3c2)c1.O=C1CCC(=O)N1Br>>Fc1cccc(-c2ccc3nnc(Br)n3c2)c1,,ClC(Cl)Cl,,,,test
US20160016948A1,C[Si](C)(C)CCOCCl.Cn1c(-c2cn[nH]c2)nc2cc(Br)ncc21>>Cn1c(-c2cnn(COCC[Si](C)(C)C)c2)nc2cc(Br)ncc21,,CN(C)C=O,,[H-].[Na+],,test
US20150031679A1,COC(=O)c1ccc2nc(Cl)c(N(C)C(C)C)nc2c1.OB(O)c1ccncc1>>COC(=O)c1ccc2nc(-c3ccncc3)c(N(C)C(C)C)nc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US06218376B1,CC(=O)OC(C)=O.CCOC(=O)C(=NO)C(=O)CCc1cccc(Cl)c1>>CCOC(=O)C(NC(C)=O)C(=O)CCc1cccc(Cl)c1,[Zn],CC(=O)OC(C)=O,,CC(=O)O,O,test
US20140011795A1,COC(=O)[C@H]1CC[C@@](C)(C(=O)OC)C1(C)C>>COC(=O)[C@@H]1CC[C@@](C)(C(=O)OC)C1(C)C,,C1CCOC1,,[H-].[Na+],,test
US20030144326A1,CS(=O)(=O)Nc1cc([C@@H](O)CN)ccc1O.O=C1CCN(c2ccc(Cn3oc(=O)[nH]c3=O)cc2)CC1>>CS(=O)(=O)Nc1cc([C@@H](O)CNC2CCN(c3ccc(Cn4oc(=O)[nH]c4=O)cc3)CC2)ccc1O,,CN(C)C=O,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130230542A1,O=C(COc1ccc(O)cc1)Nc1ccccc1>>Oc1ccc(OCCNc2ccccc2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130217709A1,CC(C)(C)OC(=O)N1C[C@@H](NC(=O)OCC[Si](C)(C)C)[C@H](c2cccc(F)c2)C1>>CC(C)(C)OC(=O)N1CC(N)C(c2cccc(F)c2)C1,,CO,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05434151,C=O.CNC.COc1cc(C(C)=O)cc(OC)c1OC>>COc1cc(C(=O)C(C)N(C)C)cc(OC)c1OC,,CCO,O,Cl,Cl,test
US04791124,CSc1ccc(-c2cnc(-c3ccc(F)cc3)s2)s1.O=C(OO)c1cccc(Cl)c1>>CS(=O)(=O)c1ccc(-c2cnc(-c3ccc(F)cc3)s2)s1,,ClCCl,,O=S(=O)([O-])[O-].[Na+].[Na+],,test
US20080090856A1,O=[N+]([O-])c1ccc(F)c(F)c1F.OCc1ccccc1>>O=[N+]([O-])c1ccc(OCc2ccccc2)c(F)c1F,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090156607A1,CCCC1CC(=O)N(Cc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)C1>>CCCC1CC(=O)N(Cc2c[nH]cn2)C1,,CC(=O)O,O,,,test
US20090156615A1,Cc1ccoc1C(=O)NCc1ccccc1.O=C1CCC(=O)N1Br>>Cc1cc(Br)oc1C(=O)NCc1ccccc1,,CC#N,,,,test
US20110059989A1,CCC[C@@H](CN)NC(=O)OC(C)(C)C.Nc1nc(N)c(C(=O)O)nc1Cl>>CCC[C@@H](CNC(=O)c1nc(Cl)c(N)nc1N)NC(=O)OC(C)(C)C,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160176861A1,CS(=O)(=O)Cl.OCCc1c(Cl)cccc1Cl>>CS(=O)(=O)OCCc1c(Cl)cccc1Cl,,ClCCl,O,,,test
US07183278B1,COC(=O)c1nc(OC)ccc1OCc1ccccc1>>COc1ccc(OCc2ccccc2)c(C(=O)O)n1,,CO,,Cl,[Na+].[OH-],test
US20030191027A1,CCOC(=O)c1ccc(Br)c(O)c1Br.NC(=O)CCl>>CCOC(=O)c1ccc(Br)c(OCC(N)=O)c1Br,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20110046132A1,CCOC(=O)c1cn[nH]c1.N#CNc1c(Br)cc(F)cc1Br>>CCOC(=O)c1cnn(C(=N)Nc2c(Br)cc(F)cc2Br)c1,,CCOCC,,C1COCCO1,Cl,test
US05242890,CCC(=O)c1noc(COc2ccc(Cl)cc2Cl)n1.NO>>CCC(=NO)c1noc(COc2ccc(Cl)cc2Cl)n1,,CO,,Cl,,test
US20050165063A1,CCCN(CCC)Cc1ccc(NC(=O)c2ccc(CN(Cc3ncc[nH]3)Cc3nccn3C)cc2)cc1.CN(C)C(=O)Cl>>CCCN(CCC)Cc1ccc(NC(=O)c2ccc(CN(Cc3nccn3C)Cc3nccn3C(=O)N(C)C)cc2)cc1,,c1ccncc1,,,,test
US20050250836A1,O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c(Br)cn1CCCO.O=[Cr](=O)=O>>O=C(O)CCn1cc(Br)c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O,,CC(C)=O,O,O=S(=O)(O)O,,test
US20150005348A1,C1CCOC1.NCC1CCCO1.O=C(O)/C=C/[C@@H]1C[C@H]1Cc1ccccc1>>O=C(/C=C/[C@@H]1C[C@H]1Cc1ccccc1)NCC1CCCCO1,,O,,CCN=C=NCCCN(C)C,Cl,test
US20090143600A1,CN(C)CC[C@@H](Oc1cccc2ccccc12)c1cccs1>>CN(C)CCC(Oc1cccc2ccccc12)c1cccs1,,CS(C)=O,,[K+].[OH-],,test
US20120295884A1,NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cnccc12.O=C(OO)c1cccc(Cl)c1>>NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2c[n+]([O-])ccc12,,CC(=O)O,,,,test
US20080090856A1,Cc1ccc(O)cn1.N#Cc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>Cc1ccc(Oc2cc(C#N)cc([N+](=O)[O-])c2)cn1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20140275568A1,CCOC(OCC)OCC.Cl.NC(=O)C(N)C(N)=O.O.O=C(O)C(=O)O>>Cl.NC(=O)c1nc[nH]c1O.O.O,,CC(C)O,O,,,test
US20070021482A1,N#Cc1cc(I)c2c(c1)ncn2-c1ccccc1.N#Cc1cccc(B(O)O)c1>>N#Cc1cccc(-c2cc(C#N)cc3ncn(-c4ccccc4)c23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20110160229A1,CC1(C)O[C@@H]2[C@@H](CC[C@H]2n2cnc3c(N)ncc(F)c32)O1.Cl>>Cl.Nc1ncc(F)c2c1ncn2[C@@H]1CC[C@@H](O)[C@H]1O,,CO,,,,test
US06458781B1,CC(C)[C@H](N)C(=O)O.CCC(C)=O>>CCC(C)N[C@H](C(=O)O)C(C)C,[Pd],CCO,,[H][H],,test
US20160222033A1,Cc1sc2nc(Cn3nc([N+](=O)[O-])cc3Cl)cc(=O)n2c1Br>>Cc1sc2nc(Cn3nc(N)cc3Cl)cc(=O)n2c1Br,[Fe],CCO,O,[Cl-].[NH4+],,test
US20150078992A1,C1CCC([NH+]2CCCC2)CC1>>C1CCC(N2CCCC2)CC1,,O,,Cl,,test
US20090209559A1,COC(=O)c1sccc1NC(=O)c1cccc(OC)c1.N>>COc1cccc(-c2nc3ccsc3c(=O)[nH]2)c1,,CO,,,,test
US06107458,CCCCCOc1ccc(-c2cc(-c3ccc(C(=O)OCC)cc3)no2)cc1>>CCCCCOc1ccc(-c2cc(-c3ccc(C(=O)O)cc3)no2)cc1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20150322045A1,CCC(C)C1NC(=O)CNC1=O>>CCC(C)C1CNCCN1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20130172323A1,CC(CC(=O)O)C(=O)c1ccc(NCc2ccccc2)c(O)c1.NN>>CC1CC(=O)NN=C1c1ccc(NCc2ccccc2)c(O)c1,,CC(=O)O,,O,,test
US20100256113A1,Cc1c(COc2ccc(CCC3(O)CCCC3)cc2)nc2ccccc2c1OCc1ccccc1>>Cc1c(COc2ccc(CCC3(O)CCCC3)cc2)[nH]c2ccccc2c1=O,[Pd],C1CCOC1,CCO,,,test
US20030207920A1,COC(=O)[C@H](CCCC1CCN(C(=O)OCc2ccccc2)CC1)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H](CCCC1CCN(C(=O)OCc2ccccc2)CC1)C(=O)O,,CO,O,[Li+].[OH-],,test
US20070037794A1,COCN(c1cc(Cl)cnc1C(=O)c1cccc(N)n1)S(=O)(=O)c1ccc(C(C)(C)C)cc1>>CC(C)(C)c1ccc(S(=O)(=O)Nc2cc(Cl)cnc2C(=O)c2cccc(N)n2)cc1,,C1COCCO1,Cl,O,,test
US05216020,CI.O=C(O)C1Cc2ccsc2S1(=O)=O>>CC1(C(=O)O)Cc2ccsc2S1(=O)=O,,CN(C)C=O,,[H-].[Na+],,test
US20120130076A1,CC(=O)c1cccc(O)c1.COc1ccc(C=O)cc1OC>>COc1ccc(C=CC(=O)c2cccc(O)c2)cc1OC,,CCO,,Cl,[K+].[OH-],test
US06005116,COc1ccc(-c2cc(O)no2)cc1>>Oc1ccc(-c2cc(O)no2)cc1,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20080200692A1,CS(=O)(=O)O.Cc1cn(-c2cc([N+](=O)[O-])cc(C(F)(F)F)c2)cn1>>CS(=O)(=O)O.Cc1cn(-c2cc([N+](=O)[O-])cc(C(F)(F)F)c2)cn1,,CCOC(C)=O,,,,test
US20080009530A1,CC(C)(C)c1cc(/C=C/C(=O)O)n(Cc2ccc(C(F)(F)F)cc2Cl)n1.CCCCCS(N)(=O)=O>>CCCCCS(=O)(=O)NC(=O)/C=C/c1cc(C(C)(C)C)nn1Cc1ccc(C(F)(F)F)cc1Cl,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US05972975,Cc1ccnc2ccccc12>>Cc1ccnc2c1CCCC2,O=[Pt],O=C(O)C(F)(F)F,,[H][H],,test
US20090197877A1,CCNC(=O)Nc1nc2cc(Br)cc(Br)c2s1.COc1cncc(B2OC(C)(C)C(C)(C)O2)c1>>CCNC(=O)Nc1nc2cc(-c3cncc(OC)c3)cc(Br)c2s1,,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150141406A1,CO.COC(=O)C1=CNC(Cl)c2ccn(C3CCCC3)c21>>COC(=O)C1=CNC(OC)c2ccn(C3CCCC3)c21,,CO,,C[O-].[Na+],,test
US20140221435A1,COC(=O)c1ccc(N)cn1.O=C(Cl)c1cc(C(F)(F)F)ccc1F>>COC(=O)c1ccc(NC(=O)c2cc(C(F)(F)F)ccc2F)cn1,,ClCCl,,c1ccncc1,,test
US20080227770A1,CCOC(=O)CCC(=O)C(NC(C)=O)C(=O)OCC.Cl>>Cl.NCC(=O)CCC(=O)O,,CCOC(C)=O,,,,test
US20060167061A1,CCc1ccc(C(COC(C)=O)OC(C)=O)nc1>>CCc1ccc(C(O)CO)nc1,,O,,[Na+].[OH-],,test
US20150274777A1,COC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](C)NC(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>COC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](C)N.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20140128372A1,Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(C(=O)NC[C@H]3CCCCN3C(=O)OC(C)(C)C)n2c1>>Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(C(=O)NC[C@H]3CCCCN3)n2c1,,CCOCC,Cl,O=C(O)C(F)(F)F,,test
US20080318947A1,C=O.CC(=O)c1ccccc1.CNC>>CN(C)CCC(=O)c1ccccc1,,CCO,,CCCCCC,CCOC(C)=O,test
US04539152,CC(C)(OC(=O)OCc1ccc([N+](=O)[O-])cc1)[C@@H]1C(=O)N[C@@H]1CC(=O)O.O=C([O-])CC(=O)OCc1ccc([N+](=O)[O-])cc1>>CC(C)(OC(=O)OCc1ccc([N+](=O)[O-])cc1)[C@@H]1C(=O)N[C@@H]1CC(=O)CC(=O)OCc1ccc([N+](=O)[O-])cc1,,C1CCOC1,,,,test
US20050090498A1,CC(=O)Nc1cc(Cl)c([N+](=O)[O-])cc1Cl.COC(=O)CC(=O)OC>>COC(=O)C(C(=O)OC)c1cc(NC(C)=O)c(Cl)cc1[N+](=O)[O-],,CS(C)=O,,[H-].[Na+],,test
US20130129753A1,CC[C@H](C)[C@@H]([C@@H](CC(=O)OC(C)(C)C)OC)N(C)C(=O)[C@@H](N)C(C)C.O=C(NC1(C(=O)O)CCCC1)OCC1c2ccccc2-c2ccccc21>>CC[C@H](C)[C@@H]([C@@H](CC(=O)OC(C)(C)C)OC)N(C)C(=O)[C@@H](NC(=O)C1(NC(=O)OCC2c3ccccc3-c3ccccc32)CCCC1)C(C)C,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05804587,Cc1cc(N=C=S)c(C)c2c(C#N)ccnc12.NCCN>>Cc1cc(NC(=S)NCCN)c(C)c2c(C#N)ccnc12,,Cc1ccccc1,,,,test
US20120252801A1,CCN1CC(C)(C)OC(=O)C1CC(=O)O.Nc1ccccn1>>CCN1CC(C)(C)OC(=O)C1CC(=O)Nc1ccccn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120264735A1,C=CCOCC(=C)Br.CC(C)OB1OC(C)(C)C(C)(C)O1>>C=CCOCC(=C)B1OC(C)(C)C(C)(C)O1,,CCOCC,,[Li]C(C)(C)C,,test
US20090012093A1,COC(=O)c1cccc(Br)c1.Nc1ccccc1>>COC(=O)c1cccc(Nc2ccccc2)c1,,Cc1ccccc1,,c1ccc(P(c2ccccc2)c2ccc3ccccc3c2-c2c(P(c3ccccc3)c3ccccc3)ccc3ccccc23)cc1,O=C([O-])[O-].[Cs+].[Cs+],test
US04160837,Cl.O=C(OCC(Cl)(Cl)Cl)N1CCC2OC2C1>>O=C(OCC(Cl)(Cl)Cl)N1CC[C@@H](Cl)[C@H](O)C1,,C1COCCO1,O,,,test
US20130303507A1,CC(C)(C)[Si](C)(C)OCCN[C@@H]1CC[C@@H](Nc2cc(-c3cccc(NCC4(C#N)CCOCC4)n3)c(Cl)cn2)CC1>>N#CC1(CNc2cccc(-c3cc(N[C@@H]4CC[C@@H](NCCO)CC4)ncc3Cl)n2)CCOCC1,,CO,ClCCl,Br,,test
US05053422,CC(C)COC(=O)CCC1NC(=O)[C@H](Cc2ccccc2)N1>>O=C1NC2CCC(=O)N2[C@H]1Cc1ccccc1,,Cc1ccccc1,,,,test
US04283532,CCN(C(=O)Cc1ccccc1Br)c1ccccc1.Nc1c(Cl)cccc1Cl>>CCN(C(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl)c1ccccc1,[Cu],Cc1ccccc1C,,O=C([O-])[O-].[K+].[K+],,test
US20040192686A1,Nc1nc2ccccc2[n+]([O-])n1>>Nc1nnc2ccccc2n1,,CCO,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20130065925A1,C/C=C/C(=O)O.COc1ccc(CCl)cc1>>C/C=C/C(=O)OCc1ccc(OC)cc1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US05273975,CCOC(=O)C1(NC=O)Cc2cccc3c2N(CCC3)C1=O>>O=CNC1Cc2cccc3c2N(CCC3)C1=O,,CO,,Cl,[Na+].[OH-],test
US04658037,COC(=O)C(C(=O)OC)c1ccc(Br)cc1[N+](=O)[O-]>>O=C1Cc2ccc(Br)cc2N1,,CS(C)=O,,[Cl-].[Li+],,test
US20150299115A1,CCSc1ccc(S(=O)(=O)NCC(F)(F)F)cc1NC(=O)Nc1cccc(C(F)(F)F)c1.O=C(OO)c1cccc(Cl)c1>>CCS(=O)c1ccc(S(=O)(=O)NCC(F)(F)F)cc1NC(=O)Nc1cccc(C(F)(F)F)c1,,C1CCOC1,,,,test
US20140018393A1,CC(C)(C)OC(=O)CCN1CC[C@H](CN(C(=O)C(F)(F)F)[C@@H]2C[C@H]2c2ccccc2)C1>>O=C(O)CCN1CC[C@H](CN[C@@H]2C[C@H]2c2ccccc2)C1,,CO,,[Na+].[OH-],,test
US20090286768A1,Clc1cnccn1.O=Cc1ccc(Oc2ccccc2)cc1>>OC(c1ccc(Oc2ccccc2)cc1)c1nccnc1Cl,,C1CCOC1,,[Li]CCCC,,test
US20120277224A1,CCOC(=O)CC(=O)c1ccc(Cl)cc1F.Nc1[nH]ncc1-c1ccccn1>>O=c1cc(-c2ccc(Cl)cc2F)[nH]c2c(-c3ccccn3)cnn12,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20080114002A1,CCS(=O)(=O)c1ccc(Sc2cc(Cl)ccc2[N+](=O)[O-])c(Cl)c1>>CCS(=O)(=O)c1ccc(Sc2cc(Cl)ccc2N)c(Cl)c1,,CC(=O)O,,[Na+].[OH-],,test
US04943582,CC(=O)Cl.CC1(C)Oc2ccc(CN)cc2[C@@H](N2CCCC2=O)[C@@H]1O>>CC(=O)NCc1ccc2c(c1)[C@@H](N1CCCC1=O)[C@H](O)C(C)(C)O2,,ClCCl,,CCN(CC)CC,,test
US20040138462A1,COc1ccc(S(=O)(=O)c2ccc(CCNCc3ccccc3)cc2)cc1.Fc1ccc(OC[C@@H]2CO2)cc1>>COc1ccc(S(=O)(=O)c2ccc(CCN(Cc3ccccc3)C[C@H](O)COc3ccc(F)cc3)cc2)cc1,,CCO,,,,test
US20040072842A1,CC(=O)OCC(=O)Cl.O=C1O[C@@H](CNC(=S)C(F)F)CN1c1cc(F)c(N2CCNCC2)c(F)c1>>CC(=O)OCC(=O)N1CCN(c2c(F)cc(N3C[C@H](CNC(=S)C(F)F)OC3=O)cc2F)CC1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20030171359A1,Clc1ncc(Br)c(Cl)n1.NCCCN1CCCC1=O>>O=C1CCCN1CCCNc1nc(Cl)ncc1Br,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20140045818A1,CI.Cc1cc2nc(O)sc2c(Br)c1[C@@H](COC(=O)C(C)(C)C)OC(C)(C)C>>Cc1cc2c(sc(=O)n2C)c(Br)c1[C@@H](COC(=O)C(C)(C)C)OC(C)(C)C,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20070078121A1,CCOC(=O)/C(C)=C/c1cccc(-n2nc(C(C)(C)C)cc2N)c1>>CCOC(=O)C(C)Cc1cccc(-n2nc(C(C)(C)C)cc2N)c1,[Pd],CO,,,,test
US07074801B1,CN1CCNCC1.Clc1ccnc2ccc(Br)cc12>>CN1CCN(c2ccnc3ccc(Br)cc23)CC1,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100273764A1,CC(Br)c1ccc(F)nc1.CC(C)(C)OC(=O)N1CCNCC1>>CC(c1ccc(F)nc1)N1CCN(C(=O)OC(C)(C)C)CC1,,CC#N,,[I-].[K+],,test
US20110105544A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNS(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)N(C)C(=O)OC(C)(C)C)cc1,CN(C)c1ccncc1,CC#N,,CCN(C(C)C)C(C)C,O,test
US20100029737A1,COC(=O)c1cc2c([nH]1)CCC2=O.Clc1ccc([Mg]Br)cc1>>COC(=O)c1cc2c([nH]1)CCC2c1ccc(Cl)cc1,[Pd],,,,,test
US20060167248A1,Nc1c(F)cc(N2CCOCC2)cc1F.O=C(O)CC1C=CCC1>>O=C(CC1C=CCC1)Nc1c(F)cc(N2CCOCC2)cc1F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20120283297A1,CCOC(=O)CCCn1ncc2cc(C#N)c(Cl)cc21.NO>>CCOC(=O)CCCn1ncc2cc(C(=N)NO)c(Cl)cc21,,CCO,,Cl,O=C([O-])O.[Na+],test
US20150210686A1,CC(C)(O)c1ccc(-c2cc3ccccc3c(=O)[nH]2)cc1.CCN(CC)S(F)(F)F>>CC(C)(F)c1ccc(-c2cc3ccccc3c(=O)[nH]2)cc1,,ClCCl,,,,test
US20060178418A1,O=C(Nc1cccnc1)c1ccc(OC(F)F)c2oc3ccccc3c12.O=C(OO)c1cccc(Cl)c1>>O=C(c1ccc(OC(F)F)c2oc3ccccc3c12)[NH+]([O-])c1cccnc1,,ClC(Cl)Cl,,,,test
US20040248941A1,Cc1c(OCC(F)(F)F)ccnc1CSc1nc2ccccc2n1C(C)OC(=O)OC1CCCCC1.O=C(OO)c1cccc(Cl)c1>>Cc1c(OCC(F)(F)F)ccnc1CS(=O)c1nc2ccccc2n1C(C)OC(=O)OC1CCCCC1,,ClCCl,,,,test
US05192785,CC(O)Cl.Oc1cccc2cccnc12>>OCCOc1cccc2cccnc12,O,Cc1ccccc1,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US06432993B1,CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(-n3ccnc3)cc2)ccc1N.O=C(O)COc1ccc(CC2SC(=O)NC2=O)cc1>>CN(C(=O)OC(C)(C)C)c1cc(Oc2ccc(-n3ccnc3)cc2)ccc1NC(=O)COc1ccc(CC2SC(=O)NC2=O)cc1,,C1CCOC1,,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20040063643A1,N#Cc1ccc2oc(=O)[nH]c2c1.O=CO>>O=Cc1ccc2oc(=O)[nH]c2c1,,O,,,,test
US20100035883A1,CNC.O=Cc1ccc(C2Nc3cccc4c(=O)[nH]nc(c34)C2c2ccc(F)cc2)cc1>>CN(C)Cc1ccc(C2Nc3cccc4c(=O)[nH]nc(c34)C2c2ccc(F)cc2)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20160039807A1,C=CCOc1ccc2c(c1)CCn1c-2cc(Cl)nc1=O.CO>>C=CCOc1ccc2c(c1)CCn1c-2cc(OC)nc1=O,,CO,,CC(C)(C)O[K],,test
US05698575,S=c1c(Br)coc2ccccc12.c1cn[nH]c1>>S=c1cc(-c2cc[nH]n2)oc2ccccc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130210798A1,Brc1ccc(C2CCNCC2)cc1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>FC(F)(F)CN1CCC(c2ccc(Br)cc2)CC1,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20100310512A1,CC(C)(C)OC(=O)N1CCCC1C(=O)O.O=C(CBr)c1ccc2cc(Br)ccc2c1>>CC(C)(C)OC(=O)N1CCCC1C(=O)OCC(=O)c1ccc2cc(Br)ccc2c1,,CC#N,,CCN(CC)CC,,test
US20090275578A1,COC(=O)c1ccccc1CBr.NCCCc1ccc(Br)cc1>>O=C1c2ccccc2CN1CCCc1ccc(Br)cc1,,Cc1ccccc1,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20030130278A1,C#CCc1ccccc1.Cn1c(=O)n(Cc2ccc(Br)cc2)c(=O)c2cc(I)ccc21>>Cn1c(=O)n(Cc2ccc(Br)cc2)c(=O)c2cc(C#CCc3ccccc3)ccc21,[Cu]I,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20130029938A1,CCCCC1(CCCC)CS(=O)(=O)c2cc(CBr)c(OC)cc2C(c2ccccc2)N1.CCOP(OCC)OCC>>CCCCC1(CCCC)CS(=O)(=O)c2cc(CP(=O)(OCC)OCC)c(OC)cc2C(c2ccccc2)N1,,Cc1ccccc1,,CCOC(C)=O,,test
US20070142362A1,CCCC(C)(C)C(=O)N(C)OC.Cl[Mg]Cc1ccccc1>>CCCC(C)(C)C(=O)Cc1ccccc1,,C1CCOC1,,,,test
US04695569,CSc1ccc(N)c(C(=O)NCCN2CCC(Nc3nc4ccccc4n3Cc3ccc(F)cc3)CC2)c1.O=C(n1ccnc1)n1ccnc1>>CSc1ccc2[nH]c(=O)n(CCN3CCC(Nc4nc5ccccc5n4Cc4ccc(F)cc4)CC3)c(=O)c2c1,,C1CCOC1,,,,test
US07893055B2,CCOC(=O)C#CC(=O)OCC.N#CC1(CCCCl)CCOCC1.NO>>CCOC(=O)CC1(C(=O)OCC)N=C2N(CCCC23CCOCC3)O1,,CCOC(C)=O,,[I-].[Na+],,test
US20070219229A1,Cc1cn(C(=O)OC(C)(C)C)c2c(Cl)ncc(C(=O)NC3CCOCC3)c12.NC1CCCCC1>>Cc1c[nH]c2c(NC3CCCCC3)ncc(C(=O)NC3CCOCC3)c12.Cl,,CCOC(C)=O,,CS(=O)(=O)O,,test
US04597902,CC(C)N.O=S(=O)(CCCCCl)c1ccccc1>>CC(C)NCCCCS(=O)(=O)c1ccccc1.Cl,,CO,ClC(Cl)Cl,,,test
US20020147191A1,CC(=O)N(Cc1ccccc1C(=O)O)c1ccccc1Oc1ccccc1.CN(C)P(=O)(N(C)C)N(C)C>>CC(=O)N(Cc1ccccc1C(=O)N(C)C)c1ccccc1Oc1ccccc1,,C1CCOC1,,O=S(Cl)Cl,,test
US20110189708A1,CC(=O)OC(C)=O.CCOC(C)=O.O=C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)CO.c1ccncc1>>CC(=O)OC[C@@H]1OC(OC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O,,c1ccncc1,,,,test
US05837704,CC(=O)OC(C)=O.CCN1c2ncccc2C(=O)N(C)c2ccc(-c3cn[nH]c3)nc21>>CCN1c2ncccc2C(=O)N(C)c2ccc(-c3cnn(C(C)=O)c3)nc21,,CC(=O)OC(C)=O,,CC(=O)[O-].[K+],,test
US20060063779A1,Cc1nc(Cl)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1.c1cn[nH]c1>>Cc1nc(-n2cccn2)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1,,CN(C)C=O,,[H-].[Na+],,test
US20050209291A1,N=C(Sc1ccccc1)c1cccs1.Nc1ccc2nc(NCCN3CCCC3)sc2c1>>N=C(Nc1ccc2nc(NCCN3CCCC3)sc2c1)c1cccs1,,CCO,,Br,,test
US20120283297A1,CC(C)Oc1ccc(C(=O)Cl)cc1Cl.CCOC(=O)CCn1ncc2c(C(=N)NO)cccc21>>CCOC(=O)CCn1ncc2c(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)cccc21,,CN(C)C=O,,CCN(CC)CC,,test
US05958924,CO.Cn1c(=O)cc(CC(=O)O)c2cc(Cl)ccc21>>COC(=O)CC1=CCN(C)c2ccc(Cl)cc21,,ClCCl,,O=S(Cl)Cl,,test
US20100305065A1,COc1ccc(CBr)cc1.Cc1cc(N2CCC(c3ccccc3)C2)c2cc(O)ccc2n1>>COc1ccc(COc2ccc3nc(C)cc(N4CCC(c5ccccc5)C4)c3c2)cc1,,CN(C)C=O,O,[H-].[Na+],,test
US20150141400A1,CCOC(=O)c1cc(C(F)(F)F)c(C=O)c(Cl)c1N>>Nc1c(C(=O)O)cc(C(F)(F)F)c(C=O)c1Cl,,CCO,,Cl,[Na+].[OH-],test
US20100249119A1,CC(C)(C)OC(=O)Nc1cccc(O)c1.O=[N+]([O-])c1ccc(Cl)nc1>>CC(C)(C)OC(=O)Nc1cccc(Oc2ccc([N+](=O)[O-])cn2)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20030171303A1,N#CCCOC(=O)CC1(CN=C=O)CCCCC1.O=C(c1ccccc1)C(O)c1ccccc1>>N#CCCOC(=O)CC1(CNC(=O)OC(C(=O)c2ccccc2)c2ccccc2)CCCCC1,,Cc1ccccc1,,,,test
US20120010189A1,Cc1cc(CN2CCN(C)CC2)ccc1OC1CN(C(=O)OC(C)(C)C)C1>>Cc1cc(CN2CCN(C)CC2)ccc1OC1CNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130244958A1,CC(C)(C)OP(=O)(OCCl)OC(C)(C)C.COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F>>COc1cc(C(=O)OCOP(=O)(OC(C)(C)C)OC(C)(C)C)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070270446A1,CC(C)(C)OC(=O)Nc1cc2ccccc2s1>>Nc1cc2ccccc2s1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090227588A1,O=C(Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)nn1)c1ccccc1Br.OB(O)c1ccccc1>>O=C(Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)nn1)c1ccccc1-c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05112385,CCCNC(=O)NOc1cc(Cl)ccc1Cl.CCOCCl>>CCCNC(=O)N(COCC)Oc1cc(Cl)ccc1Cl,,O,,O=C([O-])[O-].[K+].[K+],,test
US20110144105A1,CS(=O)(=O)c1ccc(B(O)O)cc1.Cc1ccc(S(=O)(=O)OC(=CC2CCOCC2)c2cc3cccnc3n2S(=O)(=O)c2ccccc2)cc1>>CS(=O)(=O)c1ccc(C(=CC2CCOCC2)c2cc3cccnc3n2S(=O)(=O)c2ccccc2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US03956310,O=C1NC2(CCCCC2)NC12CCCCC2.O=C=Nc1cccc2ccccc12>>O=C(Nc1cccc2ccccc12)N1C(=O)C2(CCCCC2)NC12CCCCC2,,Cc1ccccc1,,C1CN2CCN1CC2,,test
US20100311966A1,CCc1[nH]c(C(=O)O)nc1C.CO[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1N>>CCc1[nH]c(C(=O)N[C@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2OC)nc1C,CN(C)c1ccncc1,,,CCN=C=NCCCN(C)C,Cl,test
US06329370B1,COc1ccc2c(Cl)nnc(-c3ccccc3)c2c1.Cc1c(Cl)cncc1Cl>>COc1ccc2c(Cc3c(Cl)cncc3Cl)nnc(-c3ccccc3)c2c1,,CN(C)C=O,,[H-].[Na+],,test
US20060106048A1,CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)OC)c(N)c1)=NC(C)(C)C2.O=C(Cl)c1ccccn1>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(=O)OC)c(NC(=O)c3ccccn3)c1)=NC(C)(C)C2,CN(C)c1ccncc1,CN(C)C=O,,Cl,Cl,test
US20100233116A1,NCCNCc1ccccc1.NS(N)(=O)=O>>O=S1(=O)NCCN1Cc1ccccc1,,c1ccncc1,,,,test
US20130048956A1,CC(=O)n1c2ccccc2c2cc(Br)ccc21.OB(O)c1ccc(-c2nc3ccccc3s2)cc1>>CC(=O)n1c2ccccc2c2cc(-c3ccc(-c4nc5ccccc5s4)cc3)ccc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[K+].[K+],test
US20150152216A1,CC[SiH](Cl)CC.O=Cc1ccccc1.[Li]CCCC>>CCCCC1O[Si](CC)(CC)c2ccccc21,,CCOCC,,,,test
US20110039889A1,CC(C)(C)OC(=O)CCc1nccc2c(C#N)cccc12.NO>>CC(C)(C)OC(=O)CCc1nccc2c(C(=N)NO)cccc12,,CCO,,Cl,O=C([O-])O.[Na+],test
US20140315917A1,Cn1cc(-c2cc(Oc3ccc(N)cc3F)ccn2)cn1.O=C(Cl)N1CCN(C2CCOCC2)C1=O>>Cn1cc(-c2cc(Oc3ccc(NC(=O)N4CCN(C5CCOCC5)C4=O)cc3F)ccn2)cn1,,ClCCl,,O,,test
US06265421B1,CCOC(=O)C1CCCCC1=O.Oc1cc(O)cc(O)c1>>O=c1oc2cc(O)cc(O)c2c2c1CCCC2,,O=S(=O)(O)O,,,,test
US20120114739A1,C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)c1cc(C2CCN(C(=O)OCc3ccccc3)CC2)nc2ccnn12.O=C1CCC(=O)N1I>>C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)c1cc(C2CCN(C(=O)OCc3ccccc3)CC2)nc2c(I)cnn12,,CC#N,,,,test
US20100204236A1,CCC(C)(C)CC(O)CNC(=O)CCc1ccc(Br)cc1>>CCC(C)(C)CC(=O)CNC(=O)CCc1ccc(Br)cc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20130045964A1,NCc1nnn[nH]1.O=C(O)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1>>O=C(NCc1nnn[nH]1)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070161673A1,CC(=O)Cl.Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(N)n[nH]c2n1>>CC(=O)Nc1n[nH]c2nc(-c3cc(C(=O)NC4CC4)ccc3C)ccc12,,c1ccncc1,,,,test
US20130338142A1,COc1cc(Nc2nc(-c3cnc4c(c3)NCCS4)cn3ccnc23)ccc1N1CCOCC1.O=S([O-])OO>>COc1cc(Nc2nc(-c3cnc4c(c3)NCCS4=O)cn3ccnc23)ccc1N1CCOCC1,,O,,CO,,test
US20040110945A1,COC(=O)Cc1ccc(NC(=O)c2nn(C)c3ccccc23)c(Cl)c1>>Cn1nc(C(=O)Nc2ccc(CC(=O)O)cc2Cl)c2ccccc21,,Cl,,C1CCOC1,[Na+].[OH-],test
US05466706,CN.Cc1ccc2c(c1)n1c(CC(=O)O)c(-c3ccccc3)nc1n2C>>CNC(=O)Cc1c(-c2ccccc2)nc2n(C)c3ccc(C)cc3n12,,C1CCOC1,,Cl,,test
US20010018200A1,CC(=O)OC[C@H]1OC(OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.OCCBr>>CC(=O)OC[C@H]1O[C@@H](OCCBr)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,ClCCl,,CCOCC,FB(F)F,test
US20080287463A1,COC(=O)c1cnn2c(NC(C)C)c(-c3ccc(Cl)cc3Cl)c(Cl)nc12>>CC(C)Nc1c(-c2ccc(Cl)cc2Cl)c(Cl)nc2c(C(=O)O)cnn12,,C1COCCO1,,Cl,[K+].[OH-],test
US20060160865A1,CN(C(=O)Oc1ccc(NC(=O)c2ccc([N+](=O)[O-])cc2)cn1)c1ccccc1>>CN(C(=O)Oc1ccc(NC(=O)c2ccc(N)cc2)cn1)c1ccccc1,,CCOC(C)=O,,[H][H],,test
US20020013328A1,CCOC(=O)Cc1ccc(OC)c(O)c1.NC(=O)c1c(C2CC2)nn(-c2c(Cl)cc(Cl)cc2Cl)c1N>>COc1ccc(Cc2nc3n(-c4c(Cl)cc(Cl)cc4Cl)[nH]c(C4CC4)c-3c(=O)n2)cc1O,,CCO,,C,C[O-].[Na+],test
US20140221311A1,CC(C)(C)OC(=O)NC1CCN(S(=O)(=O)Cc2ccccc2Br)CC1>>NC1CCN(S(=O)(=O)Cc2ccccc2Br)CC1,,CO,Cl,,,test
US20100249075A1,CN.O=C1CCc2cc3c(cc2O1)C1CCCCC1C(c1ccc(O)cc1)C3>>CNC(=O)CCc1cc2c(cc1O)C1CCCCC1C(c1ccc(O)cc1)C2,,C1CCOC1,,,,test
US03935211,NC(=NO)C1CC1.O=C(Cl)c1cnccn1>>c1cnc(-c2nc(C3CC3)no2)cn1,,Cc1ccccc1C,,,,test
US20100173933A1,COc1ccc(Br)c(-c2nc(COc3ccc(F)c(C(N)=O)c3F)sc2Br)c1>>COc1ccc(Br)c(-c2csc(COc3ccc(F)c(C(N)=O)c3F)n2)c1,[Zn],CC(=O)O,,,,test
US20080096878A1,CC(C)(C)OC(=O)CN1CC2(CCN(CC(F)(F)F)CC2)c2ccccc21>>O=C(O)CN1CC2(CCN(CC(F)(F)F)CC2)c2ccccc21,,ClCCl,O=C(O)C(F)(F)F,,,test
US20140121377A1,CC(=O)c1ccc(Br)nc1.c1nc[nH]n1>>CC(=O)c1ccc(-n2cncn2)nc1,,CN(C)C=O,O,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20090226954A1,CCOP(=O)(CCCBr)OCC.Cc1nc2ccccc2s1>>CCOP(=O)(CCC[n+]1c(C)sc2ccccc21)OCC.[Br-],,CCOC(C)=O,,,,test
US20120214803A1,Nc1cccc2cccnc12.O=S(=O)(Cl)c1cccc(Cl)c1>>O=S(=O)(Nc1cccc2cccnc12)c1cccc(Cl)c1,CN(C)c1ccncc1,,,,,test
US20070049593A1,CC1(C)OB(c2ccc(Cl)cc2N)OC1(C)C.COC(=O)c1ccc2c(C3CCCCC3)c(Br)[nH]c2c1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccc(Cl)cc3N)[nH]c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])O.[Na+],,test
US20150361100A1,OCc1cc2ccccn2c1-c1ccc(CN2CCOCC2)s1>>O=Cc1cc2ccccn2c1-c1ccc(CN2CCOCC2)s1,O=[Mn]=O,,,,,test
US20070049603A1,CC(C)(C)[Si](C)(C)ON=C1CCc2cc(Nc3c(C(=O)C4CCOCC4)oc4cnccc34)ccc21>>O=C(c1oc2cnccc2c1Nc1ccc2c(c1)CCC2=NO)C1CCOCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050234033A1,CN(C)c1cccc2c(S(=O)(=O)Cl)cccc12.COC(=O)c1cnc(N2CCNCC2)s1>>COC(=O)c1cnc(N2CCN(S(=O)(=O)c3cccc4c(N(C)C)cccc34)CC2)s1,,ClCCl,,CCN(CC)CC,O,test
US20020103161A1,Cc1ccc(C2=NN(CCCCO)C3N=CN=C(N)C23)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(C2=NN(CCCCOS(=O)(=O)c3ccc(C)cc3)C3N=CN=C(N)C23)cc1,CN(C)c1ccncc1,O,,ClCCl,,test
US20110224202A1,COC(C(=O)N(C)OC)c1ccc(CN2CCOCC2)cc1.COc1cc(-c2ccco2)cc(OC)c1Br>>COc1cc(-c2ccc(C(=O)C(OC)c3ccc(CN4CCOCC4)cc3)o2)cc(OC)c1Br,,CCOC(C)=O,,,,test
US08129371B2,CCn1ncc2c(N3CC4CCC(C3)O4)nc(Cl)nc21.Nc1ccc(B(O)O)cc1>>CCn1ncc2c(N3CC4CCC(C3)O4)nc(-c3ccc(N)cc3)nc21,,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US05407936,CC(C)n1c(Cl)nc2cc(Cl)c([N+](=O)[O-])cc21.CN1CCNCC1>>CC(C)n1c(N2CCN(C)CC2)nc2cc(Cl)c([N+](=O)[O-])cc21,,Cc1ccccc1,,CCOC(C)=O,,test
US06455523B1,CS(=O)(=O)N1Cc2cc(C#N)ccc2N(Cc2c[nH]cn2)C[C@H]1Cc1ccccc1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CS(=O)(=O)N1Cc2cc(C#N)ccc2N(Cc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)C[C@H]1Cc1ccccc1,,CC#N,,Cl,,test
US20030225091A1,O=C(O)C(O)c1cccc(OCc2ccccc2Cl)c1OCc1ccccc1Cl>>O=C(O)C(=O)c1cccc(OCc2ccccc2Cl)c1OCc1ccccc1Cl,,CS(C)=O,O,CC(=O)OC(C)=O,,test
US20140274951A1,CC(C)(C)OC(=O)NCCOCCOCCOCCN.CC(C)(C)OC(=O)[C@H](CCC(=O)O)NC(=O)OCC1c2ccccc2-c2ccccc21>>CC(C)(C)OC(=O)NCCOCCOCCOCCNC(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC(C)(C)C,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150094328A1,FC1(F)CC=CCC1.O=C(OO)c1cccc(Cl)c1>>FC1(F)CCC2OC2C1,,ClCCl,,O=S([O-])[O-].[Na+].[Na+],,test
US20140051679A1,Cc1ccccc1C(N)C1CC1.O=C(O)c1ccc2[nH]nc(-c3ccc(N4CCOCC4)cc3)c2c1>>Cc1ccccc1C(NC(=O)c1ccc2[nH]nc(-c3ccc(N4CCOCC4)cc3)c2c1)C1CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20150087646A1,COC(=O)c1ccc(-n2nc(-c3c(Cl)cccc3I)[nH]c2=O)cc1OC.Nc1cccc(C(F)(F)F)c1>>COc1cc(-n2nc(-c3c(Cl)cccc3I)[nH]c2=O)ccc1C(=O)Nc1cccc(C(F)(F)F)c1,,Cc1ccccc1,,C[Al](C)C,,test
US05109014,C=O.O=C(Nc1ccc(C(F)(F)F)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)N1>>O=C1N(c2ccc(C(F)(F)F)cc2)CN2C(c3ccc(Cl)cc3)C(c3ccccc3)CN12,,O=CO,,,,test
US20110257198A1,CB(O)O.Cc1ccnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1Br>>Cc1ccnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06235771B1,CCI.O=Cc1cc(Br)ccc1O>>CCOc1ccc(Br)cc1C=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080081821A1,CCOC(=O)c1sc2c(F)cncc2c1Nc1ccc([Si](C)(C)C)cc1F.ClI>>CCOC(=O)c1sc2c(F)cncc2c1Nc1ccc(I)cc1F,,ClCCl,,,,test
US20100305093A1,CCc1c(C(=O)N2CCOc3ccc(-c4ccc5nc(C=O)[nH]c5c4)cc3C2)ccc(S(C)(=O)=O)c1F.NC1CC1>>CCc1c(C(=O)N2CCOc3ccc(-c4ccc5nc(CNC6CC6)[nH]c5c4)cc3C2)ccc(S(C)(=O)=O)c1F,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US06071903,COC(=O)C(CO)N(Cc1ccccc1N)S(=O)(=O)c1ccc(OC)cc1.Cc1ccc(F)cc1C(=O)Cl>>COC(=O)C1CN(C(=O)c2cc(F)ccc2C)c2ccccc2CN1S(=O)(=O)c1ccc(OC)cc1,,ClCCl,O,CCN(CC)CC,,test
US20150051190A1,CC(C)(C)OC(=O)N[C@@H]1CNC(=O)C1.N#Cc1cc(Br)ccc1F>>CC(C)(C)OC(=O)N[C@H]1CC(=O)N(c2ccc(Br)cc2C#N)C1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US04410540,CCCC1C(C(=O)c2ccc(OCc3ccccc3)cc2)N(C)C(=O)N1C>>CCCC1C(C(=O)c2ccc(O)cc2)N(C)C(=O)N1C,,CCO,,[H][H],,test
US20010000511A1,COC(=O)c1ccc2c(c1)C(c1cccs1)=CCC2(C)C>>CC1(C)CC=C(c2cccs2)c2cc(C(=O)O)ccc21,,C1CCOC1,CCO,[Na+].[OH-],,test
US20120172599A1,CC1=C(C#N)C(=C(C#N)C#N)OC1(c1ccccc1)C(F)(F)F.CCCCN(CCCC)c1ccc(C=Cc2ccc(C=O)s2)c(OC)c1>>CCCCN(CCCC)c1ccc(C=Cc2ccc(C=CC3=C(C#N)C(=C(C#N)C#N)OC3(c3ccccc3)C(F)(F)F)s2)c(OC)c1,,C1CCOC1,CCO,,,test
US20090221587A1,CC(=O)C(C)=O.COC(=O)c1cc(N)c(N)c(Cl)c1N>>COC(=O)c1cc2nc(C)c(C)nc2c(Cl)c1N,,CCO,,CCOC(C)=O,,test
US05336482,CC(C)N.CC1=NC=CC(=O)C1O>>Cc1c(O)c(=O)ccn1C(C)C,,CC(C)=O,O,C,,test
US04657899,CCOC(=O)C(NC(C)=O)C(=O)OCC.CCOP(=O)(Cc1ccccc1CBr)OCC>>CCOC(=O)C(Cc1ccccc1CP(=O)(OCC)OCC)(NC(C)=O)C(=O)OCC,,CCO,,,,test
US20070093501A1,Cc1nc(C=O)c[nH]1.NN1CCN(Cc2ccccc2)CC1>>Cc1nc(/C=N/N2CCN(Cc3ccccc3)CC2)c[nH]1,,CO,,,,test
US20130303532A1,CCOC(CC)(CBr)OCC.Nc1nccnc1Cl>>Clc1nccn2ccnc12,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US05177069,CCCCCN(CC(=O)N1CCCCC1)C(=O)C(CCC(=O)OC)CS(=O)(=O)c1ccc2ccccc2c1>>CCCCCN(CC(=O)N1CCCCC1)C(=O)C(CCC(=O)O)CS(=O)(=O)c1ccc2ccccc2c1,,CO,,[Na+].[OH-],,test
US04581377,CC(=O)CCc1ccc2c(c1)Cc1cc(O)ccc1-2.CI>>COc1ccc2c(c1)Cc1cc(CCC(C)=O)ccc1-2,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05306829,CCCCCCCCBr.O=c1c2ccccc2oc2cc(O)cc(O)c12>>CCCCCCCCOc1cc(O)c2c(=O)c3ccccc3oc2c1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110275801A1,Cc1nc([C@@H]2CC[C@@H](c3nnc4n3-c3ccc(Cl)cc3CNC4)CC2)no1.O=S(=O)(OCC(F)F)C(F)(F)F>>Cc1nc([C@@H]2CC[C@@H](c3nnc4n3-c3ccc(Cl)cc3CN(CC(F)F)C4)CC2)no1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US04625047,CC(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl.O=Cc1ccccc1F>>O=C(O)COc1ccc(C(=O)C=Cc2ccccc2F)c(Cl)c1Cl,,CCO,O,[Na+].[OH-],,test
US04478842,CCOC(=O)c1ccc(OCCn2c(-c3cccnc3)c(C)c3ccccc32)cc1>>Cc1c(-c2cccnc2)n(CCOc2ccc(C(=O)O)cc2)c2ccccc12,,Cl,,[Na+].[OH-],,test
US20030018046A1,Nc1cc[nH]n1.O=Cc1ccc(CN(Cc2nc3ccccc3[nH]2)C2CCCc3cccnc32)cc1>>c1cnc2c(c1)CCCC2N(Cc1ccc(CNc2cc[nH]n2)cc1)Cc1nc2ccccc2[nH]1,,C1CCOC1,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20120040957A1,CC(C)(C)OC(=O)NC1CCNCC1.O=C(CBr)C1CC1>>CC(C)(C)OC(=O)NC1CCN(CC(=O)C2CC2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160122342A1,C=CCCc1cc(C)nc(OC)c1CNC(=O)c1cccc(N(CC)C2CCN(C(=O)OC(C)(C)C)CC2)c1CC=C>>CCN(c1cccc2c1CC=CCCc1cc(C)nc(OC)c1CNC2=O)C1CCNCC1,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,ClCCl,,O=C(O)C(F)(F)F,,test
US06599917B1,O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1ccc(I)nc1Br>>O=S(=O)(Oc1ccc(I)nc1Br)C(F)(F)F,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20150005289A1,CO.COc1ccc(C=O)cc1OC(F)(F)F>>COc1ccc(C(=O)O)cc1OC(F)(F)F,,CC(C)=O,,,,test
US20100113458A1,NC(=S)c1cccc([N+](=O)[O-])c1.O=CCCl>>O=[N+]([O-])c1cccc(-c2nccs2)c1,,CCOC(C)=O,,CC(=O)O,[Na+].[OH-],test
US20060004069A1,Cc1cc2nc[nH]c2cc1C.O=[N+]([O-])c1ccc(CBr)cc1>>Cc1cc2ncn(Cc3ccc([N+](=O)[O-])cc3)c2cc1C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150018422A1,CCOC(=O)CC(c1cccc(COc2cnc(-c3cc(OC)ccc3F)c(CC(C)(C)C)c2)c1)C1CC1>>COc1ccc(F)c(-c2ncc(OCc3cccc(C(CC(=O)O)C4CC4)c3)cc2CC(C)(C)C)c1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20150361100A1,CC(O)c1cc2ccccn2c1-c1ccc(=O)n(CCN2CCN(C)CC2)n1.Nc1ncnc2[nH]nc(I)c12>>CC(c1cc2ccccn2c1-c1ccc(=O)n(CCN2CCN(C)CC2)n1)n1nc(I)c2c(N)ncnc21,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06015825,CCOCCl.CSc1ncn[nH]1>>CCOCn1cnc(SC)n1,,Cc1ccccc1,,,,test
US06291507B1,CCOC(=O)C(=NNc1ccccc1)C(C)=O.O=C1CCCCCC1>>CCOC(=O)c1[nH]c2c(c1C)CCCCC2,[Zn],CC(=O)O,,CC(=O)[O-].[Na+],,test
US07833995B2,CO.C[C@@]1(CCCC(F)(F)F)CC=C[C@H]2COC(=O)N2CCSc2nc(cs2)C(=O)O1>>C[C@](O)(C/C=C/[C@H]1COC(=O)N1CCSc1nc(C(=O)O)cs1)CCCC(F)(F)F,,CO,,C1CCOC1,,test
US20110003807A1,CCOC(=O)C(Cl)C(=O)c1ccccc1C(F)(F)F.Cc1nn2ccccc2c1C(N)=S>>CCOC(=O)c1sc(-c2c(C)nn3ccccc23)nc1-c1ccccc1C(F)(F)F,,CC(C)O,,Cl,,test
US20090318373A1,CO[C@@H]1O[C@H]2[C@H](OC[C@H]2OS(C)(=O)=O)[C@H]1OC.COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O>>COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1O[C@H]1CO[C@H]2[C@@H]1O[C@@H](OC)[C@@H]2OC,,CCOC(C)=O,CN(C)C=O,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20060217372A1,CCCCBr.NC(=O)c1ccc(Oc2ccc3c(c2)CCCNC3)nc1>>CCCCN1CCCc2cc(Oc3ccc(C(N)=O)cn3)ccc2C1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090149441A1,Nc1ccccc1.O=C(O)c1cn2cc(Cl)ccc2n1>>O=C(Nc1ccccc1)c1cn2cc(Cl)ccc2n1,,ClCCl,O=S(Cl)Cl,CN(C)C=O,O,test
US05026856,CCNc1ccc2c(c1)CNC2.CCn1cc(C(=O)O)c(=O)c2cc(F)c(F)cc21>>CCNc1ccc2c(c1)CN(c1cc3c(cc1F)c(=O)c(C(=O)O)cn3CC)C2,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20090258885A1,COc1ccc(C#N)c(C(=O)c2cccc(F)c2)c1>>N#Cc1ccc(O)cc1C(=O)c1cccc(F)c1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20020013321A1,COc1cccc(C2(O)CCN(Cc3ccccc3)CC2)c1.Oc1ccccc1>>COc1cccc(C2(c3ccc(O)cc3)CCN(Cc3ccccc3)CC2)c1,,[NH4+],[OH-],[Al+3].[Cl-].[Cl-].[Cl-],,test
US20160002242A1,NC(=O)c1ccc(Nc2nc(Nc3cnn(C4CCOCC4)c3)ncc2[N+](=O)[O-])cc1>>NC(=O)c1ccc(Nc2nc(Nc3cnn(C4CCOCC4)c3)ncc2N)cc1,[Pd],CO,,,,test
US20070135595A1,Cc1cc(Br)c2c(c1Br)C(=O)C(C)C2>>CC1=Cc2c(Br)c(C)cc(Br)c2C1,,C1CCOC1,CO,Cl,[BH4-].[Na+],test
US20060205794A1,CC1(C)OCc2cc([C@@H]3CN(CCCCCCOCCCCc4cccc(S(=O)C5CCCC5)c4)C(=O)O3)ccc2O1.O=C(OO)c1cccc(Cl)c1>>CC1(C)OCc2cc([C@@H]3CN(CCCCCCOCCCCc4cccc(S(=O)(=O)C5CCCC5)c4)C(=O)O3)ccc2O1,,ClCCl,,,,test
US07071175B1,CCOC(=O)C(CSC(C)=O)Cc1ccnc(NC(=O)OC(C)(C)C)c1>>CCOC(=O)C(CSC(C)=O)Cc1ccnc(N)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04378357,CCOC(=O)C(C)(C)Br.NC(N)=S>>CC1(C)SC(=N)NC1=O,,CCO,,,,test
US20100035875A1,CNC.CS(=O)(=O)c1cccc(-c2cccc3nc(Nc4ccc(C=O)cc4)nn23)c1>>CN(C)Cc1ccc(Nc2nc3cccc(-c4cccc(S(C)(=O)=O)c4)n3n2)cc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20040106650A1,COC(=O)C1CC(=O)N(c2ccc(O)cc2)C1.COC(=O)C1CC(=O)N(c2ccc(OCc3cccc(C#N)c3)cc2)C1.N#Cc1cccc(CBr)c1>>CN.CNC(=O)C1CC(=O)N(c2ccc(OCc3cccc(C#N)c3)cc2)C1,,CCO,,,,test
US05969140,COCOc1cc(=O)n(-c2cc(-c3c(CO)c(CO)cc4cc(OC)c(OC)cc34)ccn2)c2ccccc12>>COc1cc2cc(CO)c(CO)c(-c3ccnc(-n4c(=O)cc(O)c5ccccc54)c3)c2cc1OC,,C1COCCO1,CO,Cl,,test
US20030125370A1,Cc1[nH]c(C=O)c(C)c1CCC(=O)O.O=C1Cc2cc(S(=O)(=O)Cc3c(Cl)cccc3Cl)ccc2N1>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1CCC(=O)O,,CCO,,C1CCNCC1,,test
US20060069093A1,ClCCl.Nc1ccc([N+](=O)[O-])cc1.O=C(O)c1cc(F)c(F)cc1O.c1ccncc1>>COc1ccc(CNC(=O)c2cc(F)c(F)cc2O)cc1,,c1ccncc1,,CC(=O)OC(C)=O,,test
US20040034061A1,Cc1cc(N2CC=C(C(N)=O)CC2)c2cccc(Br)c2n1.OB(O)Oc1ccc(Cl)cc1Cl>>Cc1cc(N2CC=C(C(N)=O)CC2)c2cccc(-c3ccc(Cl)cc3Cl)c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],test
US20110092557A1,CC[C@H](C)[C@H](N)C(=O)O.O=[N+]([O-])c1cc([N+](=O)[O-])c(F)cc1F>>CC[C@H](C)[C@H](Nc1cc(F)c([N+](=O)[O-])cc1[N+](=O)[O-])C(=O)O,,O,,O=C([O-])O.[Na+],,test
US20100145036A1,CC(=O)c1ccc(C(=O)O)cc1.CC(C)(C)OC(=O)c1cc2cc(N)ccc2[nH]1>>CC(=O)c1ccc(C(=O)Nc2ccc3[nH]c(C(=O)OC(C)(C)C)cc3c2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20140088124A1,O=C(C[C@H]1CC[C@@H](OC2CC3CC2CN3C(=O)OCc2ccccc2)CC1)OCc1ccccc1>>O=C(O)C[C@@H]1CC[C@H](OC2CC3CC2CN3)CC1,[Pd],O,,CCO,[H][H],test
US20070191361A1,CCN(CC)C(=O)N(C1CCCCC1)C1CC2CCC(C1)N2C(=O)[C@@H](Cc1ccc(Cl)cc1)NC[C@@H]1C[C@@H](O)CN1.Cl>>CCN(CC)C(=O)N(C1CCCCC1)C1CC2CCC(C1)N2C(=O)[C@@H](Cc1ccc(Cl)cc1)NC[C@@H]1C[C@@H](O)CN1.Cl,,CCOCC,Cl,,,test
US20080234272A1,CCCCCc1ccc(CN(C(=O)C=Cc2ccc(C(F)(F)F)cc2)[C@@H](Cc2ccccc2)C(=O)OC)cc1>>CCCCCc1ccc(CN(C(=O)C=Cc2ccc(C(F)(F)F)cc2)[C@@H](Cc2ccccc2)C(=O)O)cc1,,CO,,O=C(O)CC(O)(CC(=O)O)C(=O)O,,test
US20070179173A1,BrCc1ccc(-c2ccccc2)cc1.COc1ccc(-c2ccccc2)c2c1CCC(=O)N2>>COc1ccc(-c2ccccc2)c2c1CCC(=O)N2Cc1ccc(-c2ccccc2)cc1,,CCOC(C)=O,O,CN(C)C=O,[H-].[Na+],test
US20080262021A1,Cl.O=[N+]([O-])c1ccc(CCC2=NCCN2)cc1>>Cl.Nc1ccc(CCC2=NCCN2)cc1,[Pd],CO,,,,test
US20100273744A1,COC(=O)c1ccc(Cl)c(Cn2ccc(NC(=O)c3c(F)cccc3F)n2)c1>>O=C(O)c1ccc(Cl)c(Cn2ccc(NC(=O)c3c(F)cccc3F)n2)c1,,CO,,[Na+].[OH-],,test
US20120077799A1,CC(F)(F)c1cccc(Oc2ccc(C3=CC=CN4CCS(=O)(=O)N=C34)cc2)c1>>CC(F)(F)c1cccc(Oc2ccc(C3CCCN4CCS(=O)(=O)N=C34)cc2)c1,O=[Pt]=O,C1CCOC1,CO,,,test
US20130331377A1,CC(=O)C(C)Oc1ccc([N+](=O)[O-])cc1>>Cc1oc2ccc([N+](=O)[O-])cc2c1C,,Cc1ccccc1,,O,,test
US20100105604A1,C=CCBr.COC(=O)c1ccc(OC)c(O)c1>>C=CCOc1cc(C(=O)O)ccc1OC,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120115844A1,Cn1nnc(-c2ccccc2F)c1COc1ccc(C(=O)O)cn1.NC1CCOCC1>>Cn1nnc(-c2ccccc2F)c1COc1ccc(C(=O)NC2CCOCC2)cn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20100292235A1,NCC1CCOCC1.O=c1occc2c([N+](=O)[O-])cccc12>>O=c1c2cccc([N+](=O)[O-])c2ccn1CC1CCOCC1,,CCOC(C)=O,,C1COCCO1,,test
US20050085470A1,CCC1(CC)OC(=O)N(C)c2ccc(Nc3ccc(F)c(F)c3)cc21.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCC1(CC)OC(=S)N(C)c2ccc(Nc3ccc(F)c(F)c3)cc21,,Cc1ccccc1,,,,test
US20140206694A1,C[C@H](NC(=O)c1ccccc1C(=O)O)c1cc2ccc(F)cc2nc1-c1cccc(F)c1>>C[C@@H](c1cc2ccc(F)cc2nc1-c1cccc(F)c1)N1C(=O)c2ccccc2C1=O,,CCO,,Cl,,test
US04153721,O=C(COc1ccc(-c2ccccc2)cc1Br)c1ccccc1>>Brc1cc(-c2ccccc2)cc2c(-c3ccccc3)coc12,,O,,,,test
US20120329785A1,CN1CCN(c2ccc(N)cc2)CC1.COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(Br)cc23)cc1>>CN1CCN(c2ccc(Nc3nc4ccc(Br)cc4c4c[nH]nc34)cc2)CC1,C1COCCO1,CO,,Cl,,test
US20150175562A1,BrBr.CC(=O)CC1CCCCC1>>O=C(CBr)CC1CCCCC1,,CO,,O,,test
US20150045356A1,O=C(Cl)C1CCCCC1.O=C1CCc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc2N1>>O=C1CCc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc2N1C(=O)C1CCCCC1,,ClCCl,,O,c1ccncc1,test
US20130252941A1,Clc1cccc(Cl)c1-n1cc2cnccc2n1.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1ccc2nn(-c3c(Cl)cccc3Cl)cc2c1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20130225620A1,Cc1ccc(S(=O)(=O)n2ccc3ccc(C#N)cc32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3ccc(CN)cc32)cc1,[Ni],CO,,N,,test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(c2cc(=O)n3nc4cc(F)ccc4c3[nH]2)CC1.Cl>>Cl.O=c1cc(C2CCNCC2)n2nc3cc(F)ccc3c2[nH]1,,C1COCCO1,CO,,,test
US20040204421A1,CCN1CCN(c2nc(-c3ccc(O)cc3)cc3ccccc23)CC1.CCN=C=O>>CCNC(=O)c1ccc(-c2cc3ccccc3c(N3CCN(CC)CC3)n2)cc1,,C1CCOC1,,,,test
US04737514,COc1ccc2c(c1)C(=O)c1ccc(C#N)cc1S2(=O)=O.NCCN>>COc1ccc2c(c1)C(=O)c1ccc(C3=NCCN3)cc1S2(=O)=O,,CO,,C[O-].[Na+],,test
US20070161638A1,CC(C)S(=O)(=O)N[C@H]1Cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C1.Clc1ccc(Br)nc1>>CC(C)S(=O)(=O)N[C@H]1Cc2ccc(-c3ccc(Cl)cn3)cc2C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090298807A1,CCOC(COc1ccc(CCO)cc1)OCC>>O=CCOc1ccc(CCO)cc1,,C1COCCO1,O,Cl,,test
US20050288340A1,CC(C)c1ccccc1C(=O)O.c1ccncc1>>COC(=O)c1ccccc1C(C)C,CN(C)C=O,,,O=S(Cl)Cl,,test
US04666993,C=CC(N)=O.O=C(Cl)C(=O)Cl>>C=CC1=NC(=O)C(=O)O1.Cl,,CC(Cl)Cl,,,,test
US04018802,CCCCCC(CCCC(CCCCCCC(=O)OCC)SCCO)OC(C)=O.O=S(Cl)Cl>>CCCCCC(CCCC(CCCCCCC(=O)OCC)SCCCl)OC(C)=O,,c1ccccc1,,,,test
US20050148648A1,COc1ccc(C2(C#N)CCCCC2)cc1OC>>COc1ccc(C2(CN)CCCCC2)cc1OC,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110300165A1,COC(=O)c1onc(-c2ccccc2)c1C(=O)OC>>COC(=O)c1c(-c2ccccc2)noc1C(=O)O,,CO,,O,[Li+].[OH-],test
US20110300165A1,COC(=O)CS(=O)c1ccccc1.COC(C=O)OC>>COC(=O)/C(=C\C(OC)OC)S(=O)c1ccccc1,,CC#N,,C1CCNCC1,,test
US20120253012A1,CCCCCCCCCCCCCCCC(=O)NCC(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O>>CCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O,,Cc1ccccc1,,CCN(CC)CC,O=S(Cl)Cl,test
US20100197609A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)OCCOc1ccc(-c2c(C#N)c(SCc3csc(-c4ccc(Cl)cc4)n3)nc(N3CCCC3)c2C#N)cc1.O=C(O)C(F)(F)F>>C[C@H](N)C(=O)OCCOc1ccc(-c2c(C#N)c(SCc3csc(-c4ccc(Cl)cc4)n3)nc(N3CCCC3)c2C#N)cc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20140121198A1,N#CC[C@@H]1CC[C@@H](N)CC1.O=[N+]([O-])c1cnc2ccsc2c1Cl>>N#CC[C@@H]1CC[C@@H](Nc2c([N+](=O)[O-])cnc3ccsc23)CC1,,CC(C)O,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US03980643,O=C(O)/C=C\C(=O)O.O=C(O)c1ccccn1.OCCCN1CCCNCC1>>O=C(O)/C=C\C(=O)O.O=C(O)c1ccccn1.OCCCN1CCCNCC1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090156615A1,Cc1nc(-n2cccc(OCc3ccccc3)c2=O)sc1C(=O)NCc1ccccc1>>Cc1nc(-n2cccc(O)c2=O)sc1C(=O)NCc1ccccc1,[Pd],CO,,,,test
US20150011773A1,CC(C)(C)OC(=O)N[C@H](C[C@@H](Cc1ccc(OCCCF)cc1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>N[C@H](C[C@@H](Cc1ccc(OCCCF)cc1)C(=O)O)C(=O)O,,O=C(O)C(F)(F)F,,,,test
US20100048556A1,CCOCCNC(=O)c1ccc([N+](=O)[O-])c(-n2ccnc2C2CCCCC2)c1.CI>>CCOCCN(C)C(=O)c1ccc([N+](=O)[O-])c(-n2ccnc2C2CCCCC2)c1,,CC(=O)N(C)C,O,[H-].[Na+],,test
US20140378459A1,BrCc1ccccc1.O=C(O)CCCc1ccc(O)cc1>>O=C(CCCc1ccc(O)cc1)OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070281918A1,COc1nc2c(c(Cl)c1Br)C(C)CN(C(=O)C(F)(F)F)CC2>>COc1nc2c(c(Cl)c1Br)C(C)CNCC2,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US04820719,COCC(=O)OC.O=Cc1ccccc1CCCCCCCCc1ccccc1>>COC(=O)C(OC)C(O)c1ccccc1CCCCCCCCc1ccccc1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4ccc(OC)c(OC)c4)nc(Cl)c3n2)cc1.Nc1ccc2[nH]ncc2c1>>COc1ccc(-c2nc(Nc3ccc4[nH]ncc4c3)c3[nH]ncc3n2)cc1OC,C1COCCO1,CO,,Cl,,test
US20070265225A1,CCOC(=O)CBr.C[C@H]1OC[C@@H](c2ccccc2)NC1=O>>CCOC(=O)CN1C(=O)[C@@H](C)OC[C@H]1c1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20100081825A1,CC(C)(C)[Si](C)(C)Cl.Oc1ccc2ccc(O)cc2c1>>CC(C)(C)[Si](C)(C)Oc1ccc2ccc(O)cc2c1,,CN(C)C=O,,O,c1c[nH]cn1,test
US05753664,Cc1c[nH]c2nc(S)[nH]c(=O)c12>>Cc1c[nH]c2nc[nH]c(=O)c12,[Ni],CO,,C[O-].[Na+],,test
US04593035,CC(C)N=C=O.Nc1ccc2c(c1)CCC(=O)N2>>CC(C)NC(=O)Nc1ccc2c(c1)CCC(=O)N2,,c1ccccc1,,,,test
US20070238726A1,CC=O.COc1ccc(Cn2nc(CC3CCNCC3)c3c(Oc4ccc(NC(=O)c5nccn(-c6ccc(F)cc6)c5=O)cc4F)ccnc32)cc1>>CCN1CCC(Cc2nn(Cc3ccc(OC)cc3)c3nccc(Oc4ccc(NC(=O)c5nccn(-c6ccc(F)cc6)c5=O)cc4F)c23)CC1,,C1CCOC1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20080275097A1,COc1ccc(CNc2ccc3c(Cn4ncc5c(Oc6cc(Cl)cc(C#N)c6)c(Cl)ccc54)nn(Cc4ccc(OC)cc4)c3n2)cc1>>N#Cc1cc(Cl)cc(Oc2c(Cl)ccc3c2cnn3Cc2n[nH]c3nc(N)ccc23)c1,,O=C(O)C(F)(F)F,,,,test
US20070249607A1,COc1ccc(-n2nnnc2C)cc1COCC1(c2ccccc2)CCN(C(=O)OC(C)(C)C)CC1>>COc1ccc(-n2nnnc2C)cc1COCC1(c2ccccc2)CCNCC1,,CCOC(C)=O,,Cl,,test
US20060142265A1,CN.N#Cc1c(C=O)[nH]c2ccccc12>>CNCc1[nH]c2ccccc2c1C#N,,O,,CO,[BH4-].[Na+],test
US20020132796A1,CC(=O)Cl.CC(C)c1cc(OS(=O)(=O)C(F)(F)F)ccc1CO>>CC(=O)OCc1ccc(OS(=O)(=O)C(F)(F)F)cc1C(C)C,,ClCCl,,c1ccncc1,,test
US20100029737A1,COC(=O)c1cc2c([nH]1)CCC2c1ccc(F)c(F)c1>>O=C(O)c1cc2c([nH]1)CCC2c1ccc(F)c(F)c1,,CO,,O,[Li+].[OH-],test
US04238490,CC(=O)c1c(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)n[nH]c1=O.CN(C)CCCl>>CC(=O)c1c(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nn(CCN(C)C)c1=O,,CN(C)C=O,O,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20110034464A1,COC(=O)c1ccccc1S.IC1CCCC1>>COC(=O)c1ccccc1SC1CCCC1,,C1CCOC1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20030114666A1,CC(C)(C)OC(=O)NC1(c2cccs2)CC1.CCCC[Sn](Cl)(CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)c1ccc(C2(NC(=O)OC(C)(C)C)CC2)s1,,C1CCOC1,,[Li]CCCC,,test
US20140243309A1,CC(C)(C=O)c1ccc(Br)cc1.C[Si](C)(C)C(F)(F)F>>CC(C)(c1ccc(Br)cc1)C(O)C(F)(F)F,,C1CCOC1,,Cl,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20140256719A1,CS(=O)(=O)Cl.NC1(c2nc(NCc3ccccn3)c3c(-c4ccccc4)ccn3n2)CC1>>CS(=O)(=O)NC1(c2nc(NCc3ccccn3)c3c(-c4ccccc4)ccn3n2)CC1,,ClCCl,,c1ccncc1,,test
US20120302549A1,NC1=N[C@@]2(CCc3ccc(Br)cc32)C(F)(F)CO1.OB(O)c1cncc(Cl)c1>>NC1=N[C@@]2(CCc3ccc(-c4cncc(Cl)c4)cc32)C(F)(F)CO1,,O,,COCCOC,,test
US20110053905A1,CC(C)(C)OC(=O)n1cccc1B(O)O.Nc1ccc(Oc2ccnc(Cl)c2)cc1>>CC(C)(C)OC(=O)n1cccc1-c1cc(Oc2ccc(N)cc2)ccn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20120115845A1,C1CCNC1.CS(=O)(=O)c1ccc2nc(NC(=O)NC(=O)c3cc(CBr)ccc3Cl)sc2c1>>CS(=O)(=O)c1ccc2nc(NC(=O)NC(=O)c3cc(CN4CCCC4)ccc3Cl)sc2c1,,CC#N,,,,test
US05202315,CC(=O)[O-].CC(CC(=O)OC(C)(C)C)ON=C(C#N)C#N.[NH4+]>>CC(=O)[O-].CC(CC(=O)OC(C)(C)C)ON=C(C#N)C(N)=[NH2+],,CO,,,,test
US09221804B2,COc1nc2ccc(Br)cc2c(Cl)c1Cc1ccc(C(F)(F)F)nc1.Cc1ncc(C=O)n1C>>COc1nc2ccc(C(O)c3cnc(C)n3C)cc2c(Cl)c1Cc1ccc(C(F)(F)F)nc1,,C1CCOC1,,[Li]CCCC,,test
US20150141406A1,COc1nccc2c(O)nn(-c3ccc(S(N)(=O)=O)cc3)c12.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1nccc2c(OS(=O)(=O)C(F)(F)F)nn(-c3ccc(S(N)(=O)=O)cc3)c12,,c1ccncc1,,O=C([O-])O.[Na+],,test
US04287313,C1CCCCC1.C=CC=C.CC1CO1.O=C1CCCCCO1>>C=CC=C.C=Cc1ccccc1.O=C1CCCCCO1,,C1CCCCC1,,,,test
US20120059028A1,CCCI.COC(=O)Cc1c(C)nc2sc3c(c2c1-c1ccccc1F)CCCC3>>CCCC(C(=O)OC)c1c(C)nc2sc3c(c2c1-c1ccccc1F)CCCC3,,CN(C)C=O,,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20120208840A1,CC(C)c1cc(=O)[nH]c2ncccc12.O=P(Cl)(Cl)Cl>>CC(C)c1cc(Cl)nc2ncccc12,,Cc1ccccc1,,,,test
US20090299072A1,CCOC(=O)C(CC(C)C)C(=O)OCC.O=[N+]([O-])c1ccc(Cl)cc1C(F)(F)F>>CCOC(=O)C(CC(C)C)(C(=O)OCC)c1ccc([N+](=O)[O-])c(C(F)(F)F)c1,,CN(C)C=O,,[H-].[Na+],,test
US20110172442A1,N#Cc1cccc(C=CC(=O)ON2C(=O)CCC2=O)c1.N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O>>N#Cc1cccc(C=CC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)O)c1,,C1COCCO1,,O,O=C([O-])O.[Na+],test
US20090306066A1,CC1(C)CNC[C@@H]1O.O=C(Cl)OCc1ccccc1>>CC1(C)CN(C(=O)OCc2ccccc2)C[C@@H]1O,,ClCCl,,Cl,,test
US20110105509A1,BrC1CCCC1.Cc1c(-c2nnc(O)c3ccccc23)c2ccccc2n1CC(=O)OC(C)(C)C>>Cc1c(-c2nn(C3CCCC3)c(=O)c3ccccc23)c2ccccc2n1CC(=O)O,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US05294734,C=C(C1CCN(C(C)=O)CC1)C(O)C(NC=O)C(=O)OCC.O=S(Br)Br>>CCOC(=O)C(C=C(CBr)C1CCN(C(C)=O)CC1)NC=O,,ClCCCl,,O,,test
US20120245163A1,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](C(N)=O)C1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)OC(=O)N[C@H]1CC[C@@H](C(N)=S)C1,,C1CCOC1,,CCOC(C)=O,,test
US06030967,CCOC(=O)C1N=c2ccc3c(c2=CC1(C(=O)OCC)c1ccc2c(c1)OCO2)OCO3>>O=C1OCc2c1nc1ccc3c(c1c2-c1ccc2c(c1)OCO2)OCO3,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20040097566A1,CC(C)(C)[Si](C)(C)Oc1ccc(-c2cccc(C=O)c2)cc1C12CC3CC(CC(C3)C1)C2>>O=Cc1cccc(-c2ccc(O)c(C34CC5CC(CC(C5)C3)C4)c2)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120065191A1,CN(C(=O)n1cnc(-c2cccc(N)c2)c1)C1CCCCC1.Cl.N#CN>>CN(C(=O)n1cnc(-c2cccc(NC(=N)N)c2)c1)C1CCCCC1.Cl,,CCO,,,,test
US20150072984A1,COS(=O)(=O)OC.COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(O)c(OC)c2)ccc1O>>COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC)c(OC)c2)ccc1O,,CC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100093694A1,CC(C)I.CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cccc(-c4nnn[nH]4)c3)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cccc(-c4nnn(C(C)C)n4)c3)cc12,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US04079066,CN(C)CCCl.COc1ccc2cc(C3=CC(C)(C)Oc4cc(O)ccc43)ccc2c1>>COc1ccc2cc(C3=CC(C)(C)Oc4cc(OCCN(C)C)ccc43)ccc2c1,,CCOCC,Cc1ccccc1,O,[H-].[Na+],test
US06583319B1,COc1ccc2ccccc2c1C=CC#N.C[S+](C)(C)=O>>COc1ccc2ccccc2c1[C@@H]1C[C@H]1C#N,,CS(C)=O,,[H-].[Na+],,test
US20100048636A1,O=S(=O)(Cl)c1ccc(Br)cc1.OCC1CCCCO1>>O=S(=O)(OCC1CCCCO1)c1ccc(Br)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20100298336A1,Cc1cc(O)nc(S)n1.Clc1cc(CBr)c(Cl)s1>>Cc1cc(O)nc(SCc2cc(Cl)sc2Cl)n1,,CCO,,CCN(CC)CC,,test
US20030078276A1,C=CC(=O)OC.COC(=O)c1ccc(N)o1>>COC(=O)C1=C(N)C=CC(O)(C(=O)OC)C1,,CCOC(C)=O,ClCCl,c1ccccc1,,test
US20120184582A1,CCOC(=O)c1cn(-c2ccc3c(ccn3C(C)C)c2)cn1.CN(C)C=O>>CCOC(=O)c1cn(-c2ccc3c(c2)c(C=O)cn3C(C)C)cn1,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20110098324A1,CCOC(=O)CN=C=O.CCOC(=O)CNC(=O)c1c(O)c(C(=O)OC)c(O)n(Cc2cc(C)ccc2C)c1=O.COC(=O)c1c(O)cc(=O)n(Cc2cc(C)ccc2C)c1O>>Cc1ccc(C)c(Cn2c(O)c(C(=O)Nc3cccnc3)c(O)c(C(=O)NCC(=O)O)c2=O)c1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,,test
US04644010,CCOC(=O)C(C#N)C(=O)c1ccc[nH]1.Nc1ccc(F)cc1>>N#CC(C(=O)Nc1ccc(F)cc1)C(=O)c1ccc[nH]1,,Cc1ccccc1C,,,,test
US03953449,O=C(OCCN1CCN(c2cccc(Cl)c2)CC1)c1ccccc1[N+](=O)[O-]>>Nc1ccccc1C(=O)OCCN1CCN(c2cccc(Cl)c2)CC1,[Pd],CO,,,,test
US07041667B1,CCN(CC)CC.CCN=C=NCCCN(C)C.COc1ccc(CC(=O)O)cc1.ClCCl>>COc1ccc(CC(=O)N(C)C2CCN(Cc3ccccc3)CC2)cc1,,ClCCl,,Cl,,test
US04593118,CCOC(=O)C(NC(C)=O)C(C)N>>CC(=O)NC(C(=O)O)C(C)N,,CO,,[K+].[OH-],,test
US20060160840A1,O=C(O)C1Cc2cc(O)ccc2CN1.O=C=Nc1ccc(Cl)cc1>>O=C(O)C1Cc2cc(O)ccc2C(C(=O)Nc2ccc(Cl)cc2)N1,,CN(C)C=O,,,,test
US04435403,CCOC(=O)c1cc2c(cn1)[nH]c1ccc(I)cc12.CCOP([O-])OCC>>CCOC(=O)c1cc2c(cn1)[nH]c1ccc(P(=O)(OCC)OCC)cc12,[Pd],CN1CCCC1=O,,CCN(CC)CC,,test
US20050261350A1,Cc1ccc(F)cn1.O=C1CCC(=O)N1Br>>Fc1ccc(CBr)nc1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20060063762A1,C=C[Mg]Br.CCN(CC)C(=O)Cc1ccccc1[N+](=O)[O-]>>CCN(CC)C(=O)Cc1cccc2cc[nH]c12,,C1CCOC1,,[Cl-].[NH4+],,test
US06521643B1,CC(C)(C)OC(=O)NC(=Nc1cccc(-c2ncccc2CO[Si](C)(C)C(C)(C)C)c1)NC(=O)OC(C)(C)C.Cl.ClCCl>>Cl.Cl.N=C(N)Nc1cccc(-c2ncccc2CO)c1,,C1COCCO1,ClCCl,,,test
US20100113528A1,CCCI.COC(=O)c1ccc(O)c(Cl)c1>>CCCOc1ccc(C(=O)OC)cc1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04657915,Cc1ncc([N+](=O)[O-])[nH]1.O=c1ccc2c(Br)nccc2[nH]1>>Cc1ncc([N+](=O)[O-])n1-c1nccc2[nH]c(=O)ccc12,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US04532254,COc1c(OC)c(OC)c2c(=O)cc(-c3ccc(OCc4ccccc4)c(OCc4ccccc4)c3)oc2c1OC>>COc1c(OC)c(OC)c2c(=O)cc(-c3ccc(O)c(O)c3)oc2c1OC,[Pd],CO,,CCOC(C)=O,,test
US04873243,COC1=CC(=CCl)SN1.Nc1ccc(-c2ccc(Cl)cc2)nn1>>COc1cc(Cn2nc(-c3ccc(Cl)cc3)ccc2=N)sn1.Cl,,CN(C)C=O,,,,test
US04371537,O=S(=O)(c1ccccc1)c1ccc(S(=O)(=O)c2ccccc2)nc1.Oc1ccc(Cl)c(Cl)c1>>O=S(=O)(c1ccccc1)c1ccc(Oc2ccc(Cl)c(Cl)c2)nc1,,C1CCOC1,,O,CC(C)(C)[O-].[K+],test
US20130053409A1,C=CC(=O)Cl.COc1cc(N2CC[C@@H](N(C)C)C2)c(N)cc1Nc1ncc(Cl)c(-c2c[nH]c3ccccc23)n1>>C=CC(=O)Nc1cc(Nc2ncc(Cl)c(-c3c[nH]c4ccccc34)n2)c(OC)cc1N1CC[C@@H](N(C)C)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04598075,Cn1nnnc1SCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)[C@@H](N)[C@H]2SC1.O=C(O)/C(=N\OC1CCNC1=O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>Cn1nnnc1SCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)[C@@H](NC(=O)/C(=N\OC3CCNC3=O)c3csc(NC(c4ccccc4)(c4ccccc4)c4ccccc4)n3)[C@H]2SC1,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20120225858A1,COc1ccc(C(Cl)(c2ccccc2)c2ccc(OC)cc2)cc1.NC1=N[C@@](c2cc(Br)ccc2F)(C(F)F)CCS(=O)(=O)C1>>COc1ccc(C(NC2=N[C@@](c3cc(Br)ccc3F)(C(F)F)CCS(=O)(=O)C2)(c2ccccc2)c2ccc(OC)cc2)cc1,,ClCCl,,CCN(CC)CC,,test
US20110105461A1,Cc1ccc(S(=O)(=O)OCC2COc3ccc(S(C)(=O)=O)cc3O2)cc1.NCCO>>CS(=O)(=O)c1ccc2c(c1)OC(CNCCO)CO2,,CC#N,,,,test
US20060167016A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1ccc(CN2CC3CNCC(C2)O3)cc1>>CC(C)(C)OC(=O)N1CC2CN(Cc3ccccc3)CC(C1)O2,,CC(C)(C)O,O,[Na+].[OH-],,test
US05089513,CCC(O)(c1cncc(OCc2ccc3ccccc3c2)c1)c1nccs1.CI>>CCC(OC)(c1cncc(OCc2ccc3ccccc3c2)c1)c1nccs1,,CS(C)=O,,[K+].[OH-],,test
US20150291563A1,COC(=O)C(=O)C=Cc1cccc(Br)c1.NNc1ccccc1Cl>>COC(=O)C1=NN(c2ccccc2Cl)C(c2cccc(Br)c2)C1,,CC(=O)O,,Cl,,test
US20160009710A1,CC(C)(C)[Si](C)(C)Cl.OCc1cc2nncn2cc1C1CC1>>CC(C)(C)[Si](C)(C)OCc1cc2nncn2cc1C1CC1,,ClCCl,,CCN(CC)CC,,test
US20040225009A1,CC[Si](CC)(CC)O[C@@H]1C(=O)N[C@@H]1C(C)C.O=C(Cl)c1ccccc1>>CC[Si](CC)(CC)O[C@@H]1C(=O)N(C(=O)c2ccccc2)[C@@H]1C(C)C,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070105913A1,CCCCc1ccc(C#Cc2ccc(CN(C(=O)C(C)(C)C)c3ccc4c(c3)C(=O)OC(C)(C)O4)cc2)cc1>>CCCCc1ccc(C#Cc2ccc(CN(C(=O)C(C)(C)C)c3ccc(O)c(C(=O)O)c3)cc2)cc1,,CCO,,[Na+].[OH-],,test
US04882340,O=C(O)c1cccc2cc(-c3ccccc3)oc12>>OCc1cccc2cc(-c3ccccc3)oc12,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20110300165A1,CCOC(=O)c1noc(-c2ccccc2)c1C(F)(F)CC>>CCC(F)(F)c1c(C(=O)O)noc1-c1ccccc1,,CCO,,[Na+].[OH-],,test
US20040072876A1,CC(=O)Cl.Nc1ccc(-c2csc(-c3cnccc3C(F)(F)F)n2)cc1>>CC(=O)Nc1ccc(-c2csc(-c3cnccc3C(F)(F)F)n2)cc1,,ClCCl,,c1ccncc1,,test
US20060041134A1,Cc1nc2c3c(ccn2c1C)C(=O)C(O[Si](C)(C)C(C)(C)C)C(c1ccccc1)N3>>Cc1nc2c3c(ccn2c1C)C(=O)C(O)C(c1ccccc1)N3,,CO,,Cl,N,test
US20160031899A1,C=C1CC[C@H]2[C@H](C=O)[C@@H]([C@@]3(C)CC[C@H](NC(C)=O)C[C@@H]3C=O)CC[C@]12C>>C=C1CC[C@H]2[C@H](CO)[C@@H]([C@@]3(C)CC[C@H](NC(C)=O)C[C@@H]3CO)CC[C@]12C,,C1CCOC1,CO,[BH4-].[Na+],,test
US04895951,CCCCCCCCN(CCCCCCCC)C(=O)CCl.COCCOC.NCc1ccccn1>>NC(=O)c1cccnc1C(N)=O,,CCCCCCC,,CCN(C(C)C)C(C)C,,test
US20110294836A1,CCOC(=O)CC(=O)C1CCN(C(=O)OC(C)(C)C)CC1.N=CN>>CC(C)(C)OC(=O)N1CCC(c2cc(O)ncn2)CC1,,CO,,Cl,C[O-].[Na+],test
US20070037862A1,C1CCNC1.O=C=Nc1ccc([N+](=O)[O-])cc1>>O=C(Nc1ccc([N+](=O)[O-])cc1)N1CCCC1,,CC#N,,,,test
US07737166B2,Cc1c(C=O)c(N2CC[C@H](N(C)C)C2)c2oc(C3CC3)nc2c1C#N.Cl>>Cc1c(C=O)c(N2CC[C@H](N(C)C)C2)c2oc(C3CC3)nc2c1C#N.Cl,,CCO,CCOCC,,,test
US20110053897A1,CC(C)(C)Nc1nc(Nc2cc(OC3CCN(C(=O)OC(C)(C)C)CC3)ncn2)cc2ccn(CCO)c(=O)c12>>CC(C)(C)Nc1nc(Nc2cc(OC3CCNCC3)ncn2)cc2ccn(CCO)c(=O)c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160193218A1,CC(C)N1CCC(Nc2cccc(C3OCCCO3)c2)CC1>>CC(C)N1CCC(Nc2cccc(C=O)c2)CC1,,CO,,Cl,,test
US20090275538A1,O=C(Cl)N1CCC(N2CCCCC2)CC1.Oc1cc(F)ccc1/C=C1\SC(N2CCCCN2)=NC1=S>>O=C(Oc1cc(F)ccc1/C=C1\SC(N2CCCCN2)=NC1=S)N1CCC(N2CCCCC2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04310526,CI.Cc1c(/C=C/c2ccccc2)nc2n(c1=O)C1CC1(C(=O)O)C=C2>>COC(=O)C12C=Cc3nc(/C=C/c4ccccc4)c(C)c(=O)n3C1C2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05700818,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN(C)CCNc1cc([N+](=O)[O-])cc2c1OCC2>>CN(C)CCN(C(=O)OC(C)(C)C)c1cc([N+](=O)[O-])cc2c1OCC2,,ClCCl,,CCN(CC)CC,,test
US04663336,NCC(=O)O.O=C(Cl)COc1ccccc1>>O=C(O)CNC(=O)COc1ccccc1,,CCOCC,O,[Na+].[OH-],,test
US20150065468A1,COc1cc(N)c(NC(=O)C(OC)OC)cc1OCc1ccccc1>>COc1cc2ncc(=O)[nH]c2cc1OCc1ccccc1,,CCO,O,,,test
US20100076027A1,COC(=O)c1ccc(S)cc1.CS(=O)(=O)OCC(c1c2c(nn1-c1ccc(Cl)cc1)CCCC2)C1CCCCC1>>COC(=O)c1ccc(SCC(c2c3c(nn2-c2ccc(Cl)cc2)CCCC3)C2CCCCC2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100280013A1,N#Cc1ccc2c(n1)OCCO2.O=C([O-])O.[Li]C>>CC(=O)c1ccc2c(n1)OCCO2,,C1CCOC1,,O=S(=O)(O)O,,test
US04939143,Cc1cc(C2=CC(O[Si](C)(C)C(C)(C)C)CC(C)(C)C2CO)ccc1F>>Cc1cc(C2=CC(O[Si](C)(C)C(C)(C)C)CC(C)(C)C2C=O)ccc1F,,CS(C)=O,,,,test
US04710496,CC1CC(=O)NN=C1c1ccc(N)cc1.COC1CC(C=O)C(OC)O1>>CC1CC(=O)NN=C1c1ccc(-n2ccc(C=O)c2)cc1,,CC(=O)O,,O=C([O-])O.[Na+],,test
US04999359,O=C(C1NCCc2[nH]cnc21)N1CCCC1>>c1nc2c([nH]1)CCNC2CN1CCCC1,,C1COCCO1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080287695A1,Brc1ccc(C2=CCCC2)cc1.OO>>O=C1CCCC1c1ccc(Br)cc1,,CC(C)=O,,O=CO,,test
US20110312959A1,O=C(Cl)c1ccc2nccnc2c1.O=C(Nc1cnc2[nH]c(CO)cc2c1)c1ccccc1Br>>O=C(OCc1cc2cc(NC(=O)c3ccccc3Br)cnc2[nH]1)c1ccc2nccnc2c1,,CCOC(C)=O,,CCN(CC)CC,ClCCl,test
US20070135631A1,Fc1cc(Br)cc(OC(F)(F)C(F)F)c1.O=Cc1ccc(F)c(Br)c1>>OC(c1ccc(F)c(Br)c1)c1ccc(F)cc1OC(F)(F)C(F)F,,CCOCC,,[Li]CCCC,,test
US20100179150A1,CCC(CC)(CC)C([O-])([O-])[O-].O=C(O)c1cc(Cl)ncc1[N+](=O)[O-]>>CCOC(=O)c1cc(Cl)ncc1[N+](=O)[O-],,Cc1ccccc1,,Cl,,test
US20160222014A1,O=[N+]([O-])c1ccc(N2CCCC(CO)C2)cc1>>Nc1ccc(N2CCCC(CO)C2)cc1,[Zn],CCO,O,[Cl-].[NH4+],,test
US20160185769A1,CCOC(=O)Cl.COc1ncc(Br)c2ccn(S(=O)(=O)c3ccc(C)cc3)c12>>CCOC(=O)c1cc2c(Br)cnc(OC)c2n1S(=O)(=O)c1ccc(C)cc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US04948804,CC(C)CCOC1CCC(=O)N1.O=C(Cl)c1ccccc1>>CC(C)CCOC1CCC(=O)N1C(=O)c1ccccc1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20090264445A1,CC#CC(=O)OCC.CC(C)(O)Cc1cccc(O)c1>>CCOC(=O)/C=C(\C)Oc1cccc(CC(C)(C)O)c1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20090028925A1,COCOc1ccc(Br)cc1Cc1ccc(F)cc1.Cc1cc(O[Si](C(C)C)(C(C)C)C(C)C)cc(C)c1C=O>>COCOc1ccc(C(O)c2c(C)cc(O[Si](C(C)C)(C(C)C)C(C)C)cc2C)cc1Cc1ccc(F)cc1,,C1CCOC1,,[Li]CCCC,,test
US20100273781A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.O=C(Nc1cc(Cl)ccc1Br)c1cccc(Cl)c1>>O=C(Nc1cc(Cl)ccc1C1=CCN(C(=O)O)CC1)c1cccc(Cl)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US05852051,N#Cc1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@H](N)Cc2ccccc2)cc1.O=S(=O)(O)Cl>>N#Cc1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccccc2)NS(=O)(=O)O)cc1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20120028919A1,CC(=O)N1CCc2ccc(N)cc21.CS(=O)c1ncc2ccc(-c3cccc(S(=O)(=O)N4CC[C@H](O)C4)c3)n2n1>>CC(=O)N1CCc2ccc(Nc3ncc4ccc(-c5cccc(S(=O)(=O)N6CC[C@H](O)C6)c5)n4n3)cc21,,CS(C)=O,,,,test
US20070099908A1,[N-]=[N+]=NC[C@H]1CCc2ccc(S(=O)(=O)c3cccc(F)c3)cc2O1>>NC[C@H]1CCc2ccc(S(=O)(=O)c3cccc(F)c3)cc2O1,[Pd],C1CCOC1,,[H][H],,test
US05998433,C=C(c1ccccc1)c1ccc(C(=O)N2CCc3oc(CN(C)C)cc3C2)cc1.Cl>>C=C(c1ccccc1)c1ccc(C(=O)N2CCc3oc(CN(C)C)cc3C2)cc1.Cl,,CCOC(C)=O,CO,,,test
US20010027196A1,C1CCC2=NCCCN2CC1.CS(=O)c1nc(N)nc(-n2cccn2)c1C#N>>N#Cc1c(SCCc2ccccn2)nc(N)nc1-n1cccn1,,COCCOC,,,,test
US20020115674A1,C1CCNC1.Cn1c(=O)n(O)c(=O)c2cc(F)c(F)cc21>>Cn1c(=O)n(O)c(=O)c2cc(F)c(N3CCCC3)cc21,,CC#N,,CCN(CC)CC,,test
US04455422,CS(=O)(=O)Oc1cc2c(cc1C(=O)CCCl)NC(=O)CC2>>O=C1CCc2ccc(C(=O)CCCl)cc2N1,[Pd],CCO,,[H][H],,test
US20160157491A1,C=Cc1ccc2c([N+](=O)[O-])c(OC)ccc2c1>>C=Cc1ccc2c([N+](=O)[O-])c(O)ccc2c1,,ClCCl,,BrB(Br)Br,,test
US20080242643A1,CCI.CS(=O)(=O)c1ccc(/C(COC(=O)OCCCC(CO[N+](=O)[O-])O[N+](=O)[O-])=C(/C(=O)O)c2ccccc2)cc1>>CCOC(=O)/C(=C(\COC(=O)OCCCC(CO[N+](=O)[O-])O[N+](=O)[O-])c1ccc(S(C)(=O)=O)cc1)c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100256188A1,Cn1c(Nc2cc(CNC(=O)C(C)(C)C)ccc2Cl)nc2cc(C(=O)O)c(OCC(F)F)cc21.Nc1ccc(F)c(Cl)c1>>Cn1c(Nc2cc(CNC(=O)C(C)(C)C)ccc2Cl)nc2cc(C(=O)Nc3ccc(F)c(Cl)c3)c(OCC(F)F)cc21,,C1CCOC1,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20080015199A1,COc1cc(C=O)cc(CO[Si](C(C)C)(C(C)C)C(C)C)c1OC.C[Si](C)(C)C#N.Cc1nc(-c2ccc(N)cc2)no1>>COc1cc(C(C#N)Nc2ccc(-c3noc(C)n3)cc2)cc(CO[Si](C(C)C)(C(C)C)C(C)C)c1OC,,ClCCl,,O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3],,test
US04748252,C=O.CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)OC)OCC3N>>CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)OC)OCC3O,,C1CCOC1,,O,,test
US03984467,CCCCC(=N)N.O=C=Nc1cccc(C(F)(F)F)c1>>CCCCC(=N)NC(=O)Nc1cccc(C(F)(F)F)c1,,CC(C)=O,,Cl,[Na],test
US20120245136A1,O=C1CC2(CCN(C(=O)OCc3ccccc3)CC2)Oc2ccccc21>>O=C1CC2(CCNCC2)Oc2ccccc21,[Pd],CC(C)O,,[H][H],,test
US20130225620A1,N#Cc1cc2cc[nH]c2cc1Cl>>NCc1cc2cc[nH]c2cc1Cl,[Ni],CO,N,,,test
US20130172317A1,CCSc1nc(=O)[nH]c(=O)n1Cc1ccc(Cl)cc1.COC(=O)c1coc(CCl)n1>>CCSC1NC(=O)N(c2nc(C(=O)OC)co2)C(=O)N1Cc1ccc(Cl)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04874856,C/C=C\C1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)C(NC(=O)/C(=N\OC(c3ccccc3)(c3ccccc3)c3ccccc3)c3csc(NC(c4ccccc4)(c4ccccc4)c4ccccc4)n3)[C@H]2SC1>>C/C=C/C1=C(C(=O)O)N2C(=O)C(NC(=O)/C(=N\O)c3csc(N)n3)[C@H]2SC1,,O=CO,,,,test
US04002610,CN1C(=O)c2ccccc2N(O)C(=N)C1c1ccccc1>>CN1C(=O)c2ccccc2N=C(N)C1c1ccccc1,,CCO,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US05359073,COc1cc(C(=O)N(C2CCCC2)C2CCCC2)ccc1CBr.c1cnc2nc[nH]c2c1>>COc1cc(C(=O)N(C2CCCC2)C2CCCC2)ccc1CN1CNc2ncccc21,,CN(C)C=O,,[H-].[Na+],,test
US20090099220A1,CCOC(=O)CCCOc1ccc2nc(C)cc(OCCCBr)c2c1.CCc1nc(N)nc(N)c1O>>CCOC(=O)CCCOc1ccc2nc(C)cc(OCCCOc3c(N)nc(N)nc3CC)c2c1,,CN(C)C=O,,[K+].[OH-],,test
US20090012126A1,CNc1cccc(Br)n1.N#Cc1ccccc1-c1ccc(C(=O)O)c(NCCc2cccc(F)c2)n1>>N#Cc1ccccc1-c1ccc(C(=O)NCc2cccc(Br)n2)c(NCCc2cccc(F)c2)n1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20060178532A1,CC(C)N(NC(=O)c1ccccc1)C(=O)COc1ccc(F)cc1Br.CCc1ccccc1B(O)O>>CCc1ccccc1-c1cc(F)ccc1OCC(=O)N(NC(=O)c1ccccc1)C(C)C,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20090099169A1,Cc1cc(C(=O)NCC2CCN(C(=O)OC(C)(C)C)CC2)nn1Cc1cc(C#N)cc2cc(C(C)C)oc12.Cl>>Cc1cc(C(=O)NCC2CCNCC2)nn1Cc1cc(C#N)cc2cc(C(C)C)oc12.Cl,,C1COCCO1,,,,test
US05190922,NCC1(c2ccccc2)CC1>>CC(C)(CN)C1CCCCC1,[Pt],CC(=O)O,,[H][H],,test
US20090082390A1,BrCC1CCCCN1Cc1ccccc1.c1ccc(-c2c[nH]cn2)cc1>>c1ccc(CN2CCCCC2Cn2cnc(-c3ccccc3)c2)cc1,,C1CCOC1,,[H-].[Na+],,test
US05840732,Cc1c2n(c(=O)n(Cc3ccccc3)c1=O)CCCS2>>Cc1c2n(c(=O)[nH]c1=O)CCCS2,,Cc1ccccc1,,BrB(Br)Br,CO,test
US20100331317A1,CCC1(CC)C(=O)Nc2ccc(OC)cc2NC1=O.CI.CN(C)C=O>>CCC1(CC)C(=O)N(C)c2ccc(OC)cc2N(C)C1=O,,CCOC(C)=O,,O,[H-].[Na+],test
US20090156603A1,CCOC(=O)c1ccc(Cl)c(Oc2cc(Br)cnc2N)c1.O=C(N=C=S)c1ccccc1>>CCOC(=O)c1ccc(Cl)c(Oc2cc(Br)cnc2NC(=S)NC(=O)c2ccccc2)c1,,C1CCOC1,,,,test
US20120238539A1,CNC.COC(=O)c1ccc(C(=O)O)cc1>>COC(=O)c1ccc(C(=O)N(C)C)cc1,,C1CCOC1,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100239520A1,Cc1nc(-c2ccn[nH]2)sc1C(=O)NCc1ccccc1.Fc1ccc(OCCBr)cc1>>Cc1nc(-c2ccn(CCOc3ccc(F)cc3)n2)sc1C(=O)NCc1ccccc1,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20030100770A1,COc1cccc(OCC(=O)N2CCCC2C(=O)OC(C)(C)C)c1OCC(=O)N1CCC[C@@H]1C(=O)OC(C)(C)C>>COc1cccc(OCC(=O)N2CCC[C@@H]2C(=O)O)c1OCC(=O)N1CCC[C@@H]1C(=O)O,,O=C(O)C(F)(F)F,,,,test
US20150291554A1,N#Cc1c(-c2ccc(Cc3ccccc3)cc2)nn(C2CCCN(C(=O)OCc3ccccc3)C2)c1N>>NC(=O)c1c(-c2ccc(Cc3ccccc3)cc2)nn(C2CCCNC2)c1N,,CCO,,[Na+].[OH-],,test
US20080139595A1,N#Cc1c[nH]c2nccc(Oc3ccc(N)cc3F)c12.Nc1nc(Cl)cc(C(F)(F)F)n1>>N#Cc1c[nH]c2nccc(Oc3ccc(Nc4cc(C(F)(F)F)nc(N)n4)cc3F)c12,,O,,CCO,Cl,test
US20120214803A1,Nc1cccc2cccnc12.O=S(=O)(Cl)c1cccnc1>>O=S(=O)(Nc1cccc2cccnc12)c1cccnc1,,CO,,Cl,c1ccncc1,test
US20020055639A1,CCOC(=O)c1c(C)c(-c2ncc(Cl)cc2F)nn1C>>Cc1c(-c2ncc(Cl)cc2F)nn(C)c1C(=O)O,,CS(C)=O,,Cl,[Na+].[OH-],test
US06235771B1,CCCOCCCl.CCOc1cc(Br)ccc1O>>CCCOCCOc1ccc(Br)cc1OCC,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20030050251A1,CC(C)(C)[C@@H]1OC[C@](Cc2cccc(C#N)c2)(C(=O)OCc2ccccc2)N1C=O>>N#Cc1cccc(C[C@](N)(CO)C(=O)OCc2ccccc2)c1,,O,,CO,Cl,test
US05245039,CCOC(=O)C1=C(CSCC)NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1>>CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1,,CO,,,,test
US20130029961A1,CCOC(=O)C(C)c1cnc(N)c(F)c1.CS(=O)(=O)Cl>>CCOC(=O)C(C)c1cnc(NS(C)(=O)=O)c(F)c1,,C1CCOC1,,CCN(CC)CC,,test
US20110021493A1,O=C(/C=C/CCl)N1CCc2c(sc3ncnc(Nc4ccc(Cl)c(Cl)c4)c23)C1.c1ccc(N2CCNCC2)nc1>>O=C(/C=C/CN1CCN(c2ccccn2)CC1)N1CCc2c(sc3ncnc(Nc4ccc(Cl)c(Cl)c4)c23)C1,,CN(C)C=O,,,,test
US20080113966A1,NC(N)=O.O=C(O)CC1(CC(=O)O)CCN(Cc2ccccc2)CC1>>O=C1CC2(CCN(Cc3ccccc3)CC2)CC(=O)N1,,CCO,,,,test
US20100190778A1,CC1=NN(C)S(=O)(=O)c2c1ccc(Cl)c2Cl>>CC1NN(C)S(=O)(=O)c2c1ccc(Cl)c2Cl,O=[Pt]=O,,,,,test
US20100069630A1,COC(=O)CCCC/C=C(/CNCCN1CCOCC1)COc1cccc2ccccc12>>O=C(O)CCCC/C=C(/CNCCN1CCOCC1)COc1cccc2ccccc12,,C1CCOC1,O,[Li+].[OH-],,test
US20120122843A1,C=O.Cc1ccc(C2CNCc3ccc(Cl)nc3O2)nc1.[BH3-]C#N>>Cc1ccc(C2CN(C)Cc3ccc(Cl)nc3O2)nc1.N,,CO,,CC(=O)O,,test
US20100022513A1,CCCc1sc(N)nc1-c1ccc(F)cc1.O=C(O)[C@@H]1CCCN1c1nc2ccccc2o1>>CCCc1sc(NC(=O)[C@@H]2CCCN2c2nc3ccccc3o2)nc1-c1ccc(F)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150065705A1,CSC(=N)N.O=C(n1ccnc1)n1ccnc1>>CSC(=N)NC(=O)n1ccnc1,,[Na+],[OH-],O=S(=O)(O)O,,test
US20090275590A1,Cn1c2c(c3ccc(Br)cc31)CCN(C(=O)OC(C)(C)C)C2>>Cn1c2c(c3ccc(Br)cc31)CCNC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030036652A1,COc1cccc(B(O)O)c1.Nc1ccc(I)cc1C(=O)O>>COc1cccc(-c2ccc(N)c(C(=O)O)c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US05340802,C=C[Mg]Br.CC(C)(C)OC(=O)NCC=O>>C=CC(O)CNC(=O)OC(C)(C)C,,C1CCOC1,,,,test
US05840732,Cl.O=C1SC(=CCCCc2ccccc2)C(=O)N1CCCCSc1cccc2nccn12>>Cl.O=C1SC(=CCCCc2ccccc2)C(=O)N1CCCCSc1cccc2nccn12,,CO,,,,test
US20070135479A1,CC(C)(C)OC(=O)N1CCC[C@H](Oc2ccc3c(N)nccc3c2)C1.O=C(Cl)c1ccccc1C(=O)Cl>>CC(C)(C)OC(=O)N1CCC[C@H](Oc2ccc3c(N4C(=O)c5ccccc5C4=O)nccc3c2)C1,,O,,CCN(CC)CC,,test
US20010034357A1,C=Cc1ccnc(-c2cc(OC[C@@H](C)N)cnc2Cl)c1.Cc1ccc(S(=O)(=O)O)cc1>>C=Cc1ccnc(-c2cc(OC[C@@H](C)N)cnc2Cl)c1.Cc1ccc(S(=O)(=O)O)cc1,,CCOC(C)=O,,CCOCC,O,test
US04218448,CC(=O)CC(=O)N1CCCc2cc(C(O)(C(F)(F)F)C(F)(F)F)ccc21>>Cc1cc(=O)n2c3c(cc(C(O)(C(F)(F)F)C(F)(F)F)cc13)CCC2,,O=S(=O)(O)O,,,,test
US08748462B2,CCOC(=O)c1ccc(O)c(Cl)c1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(Cl)c1,CN(C)c1ccncc1,ClCCl,,,,test
US04780556,CCCCCC[Si](C)(C)O.O=C(Cl)Cl>>CCCCCC[Si](C)(C)Cl,,ClCCCl,,CN(C)C=O,,test
US20060100425A1,CC(C)(C)OC(=O)CBr.Cc1cc2ccccc2n1C=O>>Cc1c(C=O)c2ccccc2n1CC(=O)OC(C)(C)C,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20020022605A1,CCCCOc1ccc(S(=O)(=O)Cl)cc1.OC1CCNC1>>CCCCOc1ccc(S(=O)(=O)N2CCC(O)C2)cc1,,ClCCl,O,CCN(CC)CC,O=C([O-])[O-].[Na+].[Na+],test
US05162336,C=O.N[C@H](Cc1c[nH]c2ccccc12)C(=O)O>>O=C(O)[C@H]1Cc2c([nH]c3ccccc23)CN1,,O,,Cl,[Na+].[OH-],test
US20070197584A1,Brc1ccc(COc2ccccn2)cc1.O=C=O>>O=C(O)c1ccc(COc2ccccn2)cc1,,C1CCOC1,O,[Li]CCCC,,test
US20130079306A1,CCO.Cn1cc(Br)cc1C(=O)C(Cl)(Cl)Cl>>CCOC(=O)c1cc(Br)cn1C,,CCO,,C,C[O-].[Na+],test
US20050214287A1,CC1CCCCN1C(=O)CCNc1cccc(-c2ccccc2)c1>>CC1CCCCN1CCCNc1cccc(-c2ccccc2)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070105904A1,C#Cc1ccc(N)nc1N.Cc1ccnc(OCc2ccc(CC(Cl)=NO)cc2)c1>>Cc1ccnc(OCc2ccc(Cc3cc(-c4ccc(N)nc4N)on3)cc2)c1,,O,,C1CCOC1,CCN(CC)CC,test
US20130143863A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.O=C1c2ccc(Cl)cc2CCN1c1cncc(Br)c1>>O=C1c2ccc(Cl)cc2CCN1c1cncc(-c2cn[nH]c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US20160075657A1,C[C@H](NC(=O)OC(C)(C)C)c1ccc(C=O)cc1.Cl.FC1(F)CC1COc1ccc2c(c1)CCNC2>>C[C@H](N)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1.Cl,,C1CCOC1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160002175A1,COc1ccc(B(O)O)c(C)c1C.Nc1nc(Cl)cc(NCCCN2CCCC2=O)n1>>COc1ccc(-c2cc(NCCCN3CCCC3=O)nc(N)n2)c(C)c1C,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20080221110A1,CC(C)(C)OC(=O)NC1CCNCC1.Cc1ccc(S(=O)(=O)OC2(CO)Cn3c(=O)ccc4ccc(F)c2c43)cc1>>CC(C)(C)OC(=O)NC1CCN(CC2(O)Cn3c(=O)ccc4ccc(F)c2c43)CC1,,CCO,,O,O=C([O-])[O-].[Na+].[Na+],test
US20090137609A1,CCOC(=O)Cc1ccc(-c2ccc(C(CC)(CC)c3ccc(C#CC4(O[Si](C)(C)C)CCCCC4)c(C)c3)cc2C)nc1>>CCC(CC)(c1ccc(C#CC2(O)CCCCC2)c(C)c1)c1ccc(-c2ccc(CC(=O)O)cn2)c(C)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20060154975A1,CC(=O)Nc1nc(CCl)cs1.Oc1ccccc1>>CC(=O)Nc1nc(COc2ccccc2)cs1,,C1CCOC1,CCO,[H-].[Na+],,test
US20110015225A1,CC(C)(C)OC(=O)NCCN.O=S(=O)(Cl)CCCCl>>Cl.NCCN1CCCS1(=O)=O,,C1CCOC1,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20090054402A1,CC(=O)OC(C)(C)C.COC(=O)c1ccc(Br)c(C)c1>>Cc1cc(C(=O)OC(C)(C)C)ccc1Br,,C1CCOC1,CCOC(C)=O,CC(C)(C)[O-].[K+],,test
US20100004259A1,Cc1ccc(F)cc1CO[C@H]1CCc2ccc(N3CCNC[C@H]3C)nc21.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>Cc1ccc(F)cc1CO[C@H]1CCc2ccc(N3CCNC[C@H]3C)nc21.O=C(O)[C@H](O)[C@@H](O)C(=O)O,,CC(C)O,,,,test
US20110130365A1,COC(=O)[C@@H](CC1CCCC1)OS(=O)(=O)C(F)(F)F.O=c1ccc(C(F)(F)F)c[nH]1>>COC(=O)[C@H](CC1CCCC1)n1cc(C(F)(F)F)ccc1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20140256756A1,CN(C)c1nsc(N2CCC(NC(=O)OC(C)(C)C)CC2)n1>>CN(C)c1nsc(N2CCC(N)CC2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120316169A1,COC(=O)C(C)(C)c1ccc(OS(=O)(=O)C(F)(F)F)cc1>>CC(C)(C(=O)O)c1ccc(OS(=O)(=O)C(F)(F)F)cc1,,CC(=O)O,,Cl,,test
US20010046471A1,N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(=O)O.O=N[O-]>>N[C@@H](CCC(=O)N[C@@H](CSN=O)C(=O)NCC(=O)O)C(=O)O,,O,,Cl,,test
US20060217562A1,CCOC1=CC(=O)C(C(=O)C(=O)OC(C)(C)C)C1.NNCc1ccccc1>>CC(C)(C)OC(=O)c1nn(Cc2ccccc2)c2c1CC(=O)C2,,CCO,,CC(=O)O,Cl,test
US20100160317A1,CN(C)C=O.Cc1c[nH]c2c1C(=O)N(C[C@@H](O)CN1CCOCC1)CC2>>Cc1c(C=O)[nH]c2c1C(=O)N(C[C@@H](O)CN1CCOCC1)CC2,,ClCCl,,O=P(Cl)(Cl)Cl,,test
US05965591,CC(=O)Cl.CC(C)(C)OC(=O)NCCOc1noc2ccc(O)cc12>>CC(=O)Oc1ccc2onc(OCCN)c2c1.Cl,,C1CCOC1,,CCN(CC)CC,,test
US20040132810A1,COc1ccccc1O.O=S(=O)(O)O>>COc1cc(S(=O)(=O)O)ccc1O,,O,,,,test
US20070078279A1,CCOC(=O)CC(=O)C(Cl)(Cl)Cl>>CCOC(=O)CC(O)C(Cl)(Cl)Cl,,CCO,,,,test
US05155113,O=C(Cl)c1ccc(OCc2ccccc2)cc1.O=c1cc(O)c(Cl)c[nH]1>>O=C(Oc1cc(=O)[nH]cc1Cl)c1ccc(OCc2ccccc2)cc1,,c1ccncc1,,,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Nc1cc(F)c(F)c(F)c1>>COc1ccc2nc(Nc3cc(F)c(F)c(F)c3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US20140350043A1,C=CC(=O)OC.[C-]#[N+]CS(=O)(=O)c1ccccc1C>>COC(=O)c1cc[nH]c1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US06815465B1,C[C@H]1C[C@@H](C)C[C@H](C)[C@@H](O)C(C#N)=CC=CC[C@@H]([C@@H]2CCC[C@H]2C(=O)O)OC(=O)C[C@H](O)[C@@H](C)C1.NC1CCCCC1>>C[C@H]1C[C@@H](C)C[C@H](C)[C@@H](O)C(C#N)=CC=CC[C@@H]([C@@H]2CCC[C@H]2C(=O)O)OC(=O)C[C@H](O)[C@@H](C)C1.[NH-]C1CCCCC1,,CCOC(C)=O,ClC(Cl)Cl,,,test
US20100331293A1,CCCC[Sn](CCCC)(CCCC)c1ccc(C)cn1.Cc1c(Cl)nc2cc(F)cc(F)c2c1Cl>>Cc1ccc(-c2nc3cc(F)cc(F)c3c(Cl)c2C)nc1,,Cc1ccccc1,,,,test
US05863947,CN(C)C=O.O=Cc1ccc(Br)cc1F>>N#Cc1ccc(C=O)c(F)c1,,Cl,,O,,test
US05136090,CCOC(=O)CCc1ccc(O)c(-c2cc(CCC(=O)OCC)ccc2O)c1.Fc1cc(Br)ccc1CBr>>CCOC(=O)CCc1ccc(O)c(-c2cc(CCC(=O)OCC)ccc2OCc2ccc(Br)cc2F)c1,[Cu],CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120157439A1,COC(=O)c1c(F)ccc(N)c1Cl.O=S(=O)(Cl)CC1CC1>>O=C(O)c1c(F)ccc(NS(=O)(=O)CC2CC2)c1Cl,,C1CCOC1,,CCN(CC)CC,[Na+].[OH-],test
US20030087957A1,O=Cc1ccc(OCc2ccccc2)cc1.ONC1CCCC1>>[O-][N+](=Cc1ccc(OCc2ccccc2)cc1)C1CCCC1,,ClC(Cl)Cl,,,,test
US20150125884A1,CCN(CCNC(=O)OC(C)(C)C)c1ccc(C(c2ccc(N(C)C)cc2)c2ccc(N(C)C)cc2)cc1.Cl>>CC[N+](CCN)=C1C=CC(=C(c2ccc(N(C)C)cc2)c2ccc(N(C)C)cc2)C=C1.[Cl-],,O,,CCOC(C)=O,,test
US20080014189A1,N#C[Cu].Nc1nc(Nc2ccc(N3CCOCC3)cc2)nn1-c1ccc(I)cc1F>>N#Cc1ccc(-n2nc(Nc3ccc(N4CCOCC4)cc3)nc2N)c(F)c1,,CN(C)P(=O)(N(C)C)N(C)C,,O,,test
US20030134860A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(CNCCO)Nc1cccc2ccc(O)cc12>>CC(C)(C)OC(=O)N(CCO)CC(=O)Nc1cccc2ccc(O)cc12,,C1CCOC1,,,,test
US20090306066A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)N(C(=O)OC(C)(C)C)c1nc(Cl)nc(N2CC(C)(N3CCCC3)C2)c1F>>CC(C)Nc1nc(Cl)nc(NN)c1F,,C1COCCO1,Cl,CO,,test
US08088815B2,COC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)cc1OC>>COc1cc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)ccc1C(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20050277670A1,O=C(c1ccc(Br)cc1)C1CCN(C(=O)C(F)(F)F)CC1>>O=C(c1ccc(Br)cc1)C1CCNCC1,,CO,,O,O=C([O-])[O-].[K+].[K+],test
US20020156087A1,NCCNc1ccc([N+](=O)[O-])cn1.O=S(=O)(Oc1ccc(-c2nccn2S(=O)(=O)C(F)(F)F)c(-c2ccc(Cl)cc2Cl)n1)C(F)(F)F>>O=[N+]([O-])c1ccc(NCCNc2ccc(-c3ncc[nH]3)c(-c3ccc(Cl)cc3Cl)n2)nc1,,CC(=O)N(C)C,,,,test
US20160024110A1,CO.COc1cc(CC(=O)O)c(Cl)cc1Cl>>COC(=O)Cc1cc(OC)c(Cl)cc1Cl,,CCOCC,,O=S(=O)(O)O,,test
US20050277670A1,O=C(c1ccc(Br)cc1)C1CCNCC1.Oc1ccccc1O>>Brc1ccc(C2(C3CCNCC3)Oc3ccccc3O2)cc1,,Cc1ccccc1C,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US04678500,COC(=O)c1cccc([N+](=O)[O-])c1CS(=O)(=O)Cl.[NH4+]>>COC(=O)c1cccc([N+](=O)[O-])c1CS(N)(=O)=O,,C1CCOC1,,O,,test
US20080139558A1,CNC.Cc1nc(Cl)sc1C(=O)N(Cc1cc(=O)[nH]c2c(F)cccc12)c1ccc(F)c(Cl)c1>>Cc1nc(N(C)C)sc1C(=O)N(Cc1cc(=O)[nH]c2c(F)cccc12)c1ccc(F)c(Cl)c1,,CN(C)C=O,,Cl,,test
US06169107A,CCOC(=O)c1cc2cccc(NC(=O)CCc3ccccc3)c2n1C.Cl.N=C(N)N>>CNC(N)=NC(=O)c1cc2cccc(NC(=O)CCc3ccccc3)c2[nH]1.Cl,,CO,,C[O-].[Na+],,test
US20110021522A1,COc1ccc2cc(C(=O)O)c(=O)oc2c1OC.Nc1cccc(-c2cn3ccccc3n2)c1>>COc1ccc2cc(C(=O)Nc3cccc(-c4cn5ccccc5n4)c3)c(=O)oc2c1OC,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04978476,CI.NCCCCO.O=Cc1ccc(F)cc1>>CN(CCCCO)c1ccc(C=O)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130165651A1,COC(=O)[C@@H]1CC[C@@H](C(=O)ON2C(=O)CCC2=O)CC1.NCc1nnc(N)[nH]c1=O>>COC(=O)[C@@H]1CC[C@@H](C(=O)NCc2nnc(N)[nH]c2=O)CC1,,C1CCOC1,CC#N,O,O=C([O-])O.[Na+],test
US20110118261A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNC1CCN(C(=O)OCc2ccccc2)CC1>>CN(C(=O)OC(C)(C)C)C1CCN(C(=O)OCc2ccccc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20140243548A1,CCCCC/C=C\C/C=C\CCCCCCCC(=O)O.CCCCCCCCCCCCCCCC(=O)OCC(O)COC(C)=O>>CCCCC/C=C\C/C=C\CCCCCCCC(=O)OC(COC(C)=O)COC(=O)CCCCCCCCCCCCCCC,CN(C)c1ccncc1,,,,,test
US05489570,O=C(O)c1cccc2c1OC(F)(F)O2.O=S(Cl)Cl>>O=C(Cl)c1cccc2c1OC(F)(F)O2,,ClCCCl,,CN(C)C=O,,test
US20060194780A1,CCOC(=O)N1C2CCC1CC(c1ccc(Cl)cc1C(CC)NC(C)=O)C2.C[Si](C)(C)I>>CCC(NC(C)=O)c1cc(Cl)ccc1C1CC2CCC(C1)[NH2+]2.[I-],,ClCCl,,,,test
US20100137281A1,CCc1cc2c(=O)[nH]c(=O)n(Cc3ccc(-c4ccc(F)cc4C#N)cc3)c2s1.COc1ccc(C(=O)CBr)cc1>>CCc1cc2c(=O)n(CC(=O)c3ccc(OC)cc3)c(=O)n(Cc3ccc(-c4ccc(F)cc4C#N)cc3)c2s1,,CCOC(C)=O,,CN(C)C=O,[H-].[Na+],test
US20110237565A1,CC(C)(C)OC(=O)N1CCN(c2ncc(-c3cccs3)nc2CNC=O)CC1>>c1csc(-c2cnc(N3CCNCC3)c3cncn23)c1,,Cc1ccccc1,,O=P(Cl)(Cl)Cl,O=C([O-])O.[Na+],test
US20090275756A1,CCC[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](C3CC(=O)O3)CC2)CC1>>C=C[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](CCC)CC2)CC1,,CCCCCCC,,,,test
US05250527,Cc1ncc(F)c([N+](=O)[O-])c1C.O=P(Cl)(Cl)Cl>>Cc1c(Cl)c(F)c[n+]([O-])c1C,,ClCCl,,[Na+].[OH-],,test
US20050113340A1,COc1cc(Cn2cnc3c(Cl)nc(N)nc32)c(Br)c(OC)c1OC.N>>COc1cc(Cn2cnc3c(N)nc(N)nc32)c(Br)c(OC)c1OC,,CO,,,,test
US20100136136A1,Cc1cc(OCCCN2CCOCC2)ccc1[N+](=O)[O-]>>Cc1cc(OCCCN2CCOCC2)ccc1N,[Pd],,,,,test
US04410539,COC(=O)c1cc2c(OC)cc(Cc3ncc[nH]3)cc2s1>>O=C(O)c1cc2c(O)cc(Cc3ncc[nH]3)cc2s1,,CC(=O)O,,Br,,test
US20140018313A1,CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O.O=C1c2ccc(Br)c(F)c2CCC1Br>>CC(C)(C)OC(=O)N1CCCC1C(=O)O[C@H]1CCc2c(ccc(Br)c2F)C1=O,,CC#N,CCOC(C)=O,CCN(CC)CC,,test
US20140364620A1,CC1(C)OCC(CBr)(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)CO1.O=[N+]([O-])c1ncc[nH]1>>CC1(C)OCC(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)(Cn2ccnc2[N+](=O)[O-])CO1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050215630A1,COC(=O)C(Cl)Cc1ccc(CCOc2ccc(O)cc2)cc1.CS(=O)(=O)Cl>>COC(=O)C(Cl)Cc1ccc(CCOc2ccc(OS(C)(=O)=O)cc2)cc1,,ClCCl,,CCN(CC)CC,,test
US20160272617A1,Cc1cc(C(=O)NC2CC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc3[nH]nnc3c2)cc1.Cl>>Cc1cc(C(=O)NC2CC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc3[nH]nnc3c2)cc1.Cl,,C1COCCO1,CO,,,test
US20120141414A1,BrCCCCCOC1CCCCO1.COC(=O)c1csc(-c2cccc(O)c2)n1>>COC(=O)c1csc(-c2cccc(OCCCCCOC3CCCCO3)c2)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110052534A1,CC(C)O.CCCOc1ccc(-c2cc(C(C(=O)OC)n3cc4nc(-c5cccc(F)c5F)nc-4cn3)on2)c(C(F)(F)F)c1>>CCCOc1ccc(-c2cc(C(C(=O)OC(C)C)n3cc4nc(-c5cccc(F)c5F)nc-4cn3)on2)c(C(F)(F)F)c1,,CCOC(C)=O,,CC(=O)O,O=C([O-])[O-].[K+].[K+],test
US20100105667A1,CCOC(=O)c1ccc(-c2c(F)c(OC)cc(OC)c2F)c2nccnc12.CN1CCN(Cc2ccc(N)nc2)CC1(C)C>>COc1cc(OC)c(F)c(-c2ccc(C(=O)Nc3ccc(CN4CCN(C)C(C)(C)C4)cn3)c3nccnc23)c1F,,CO,ClCCl,O=C([O-])O.[Na+],,test
US20100068204A1,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.O=c1cc(Oc2cccc(Br)c2)c2ccccc2[nH]1>>Nc1ccc(-c2cccc(Oc3cc(=O)[nH]c4ccccc34)c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US06326372B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(CC(=O)O)c1ccc(F)c(F)c1>>CC(C)(C)OC(=O)NC(CC(=O)O)c1ccc(F)c(F)c1,,C1CCOC1,O,CCN(CC)CC,,test
US20150315186A2,Cc1c(Br)c([N+](=O)[O-])cc(OC(=O)[O-])c1C(C)(C)C>>CC(C)(C)c1cc(Br)c([N+](=O)[O-])cc1O,,CO,,Cl,[K+].[OH-],test
US20080275043A1,CC1(N)CCCCC1.O=C(Cl)CCCCl>>CC1(NC(=O)CCCCl)CCCCC1,,C1CCOC1,,CCN(CC)CC,O,test
US06255494B1,CC(C)(C)OC(=O)N1CCC(CCCn2c(COc3ccc(Cl)cc3)nc3c(O)cccc32)CC1.CC(C)Br.O=C(O)C(F)(F)F>>CC(C)Oc1cccc2c1nc(COc1ccc(Cl)cc1)n2CCCC1CCN(C(=O)OC(C)(C)C)CC1.O=C(O)C(F)(F)F,,CN(C)C=O,,[H-].[Na+],,test
US20140080800A1,Nc1ccc(Br)cc1NC(=O)N1CCCC1.OB(O)c1cccnc1>>Nc1ccc(-c2cccnc2)cc1NC(=O)N1CCCC1,[Pd],C1CCOC1,O,O=C([O-])O.[Na+],,test
US04731364,OC1c2ccc(Cl)cc2SCC1Br.c1c[nH]cn1>>O[C@H]1c2ccc(Cl)cc2S[C@H]1Cn1ccnc1,,O,,CC#N,,test
US20100305122A1,CC(C)(C)OC(=O)NCC1CCCNC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NCC1CCCN(S(C)(=O)=O)C1,,ClCCl,,CCN(CC)CC,,test
US06432976B1,CCOC(=O)N1C2CC(=Cc3ccccc3)CC1C(OC1CCCCO1)C2>>CCOC(=O)N1C2CC(Cc3ccccc3)CC1C(OC1CCCCO1)C2,[Pt],,,,,test
US04895861,COS(=O)(=O)OC.N#CCC(O)c1ccc2ccccc2c1>>COC(CC#N)c1ccc2ccccc2c1,,C1CCOC1,O,[H-].[Na+],,test
US20100035906A1,CC(=O)Cl.Cl.NCc1ccnc(-n2[nH]cc(-c3cccnc3)c2=O)c1>>CC(=O)NCc1ccnc(-n2[nH]cc(-c3cccnc3)c2=O)c1.Cl,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20070099990A1,Cc1ccc(C(=O)COc2cc(C)cc(C)c2C)nc1>>Cc1ccc(-c2coc3c(C)c(C)cc(C)c23)nc1,,CCCCCC,CCOC(C)=O,,,test
US20100210622A1,CC(C)(C)OC(=O)n1nc(-c2ccc(OCc3ccccc3)cc2)c(C#N)c1N>>CC(C)(C)OC(=O)n1nc(-c2ccc(O)cc2)c(C#N)c1N,[Pd],CCO,,[H][H],,test
US20130150344A1,COC(=O)C1(c2c(F)cccc2[N+](=O)[O-])CCC1>>O=C1Nc2cccc(F)c2C12CCC2,[Zn],CC(=O)O,,,,test
US20150065464A1,CCOC(=O)Cl.Cc1cc2cc(Br)cnc2[nH]1>>CCOC(=O)c1cnc2[nH]c(C)cc2c1,,C1CCOC1,,[Li]CCCC,,test
US20090226398A1,ClCc1ccc(Cl)nn1.Fc1cccc(-c2nc3cnncc3[nH]2)c1F>>Fc1cccc(-c2nc3cnn(Cc4ccc(Cl)nn4)cc-3n2)c1F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100179128A1,CCCCCn1c(=O)n(CCCN)c(=O)c2[nH]c(Cl)nc21.O=C(n1ccnc1)n1ccnc1.OCCc1cccnc1>>CCCCCn1c(=O)n(CCCNC(=O)OCCc2cccnc2)c(=O)c2[nH]c(Cl)nc21,,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US20150051199A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccc(NCc2ccc(OC)cc2)nc1>>COC(=O)c1ccc(N(Cc2ccc(OC)cc2)C(=O)OC(C)(C)C)nc1,CN(C)c1ccncc1,ClCCl,,,,test
US20020019378A1,C=CCOC(=O)CC(=O)OCC=C.CC(=O)OCC(=O)C1=CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C>>C=CCOC(=O)C(C(=O)OCC=C)[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@H]1C(=O)COC(C)=O,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20070072873A1,COC(=O)c1cscc1NC(=O)COc1ccc(-c2ccc(F)cc2)cc1>>O=C(COc1ccc(-c2ccc(F)cc2)cc1)Nc1cscc1C(=O)O,,CCO,,[Na+].[OH-],,test
US20040127574A1,CC(C)(C)OC(=O)NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccc(F)cc1.Cl>>Cl.NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccc(F)cc1,,CCO,,,,test
US05556863,CCCC(=O)c1cnc2c(OCCSC)cccc2c1Nc1c(C)cccc1Cl.[O-]Cl>>CCCC(=O)c1cnc2c(OCCS(C)=O)cccc2c1Nc1c(C)cccc1Cl,,ClCCl,,O,,test
US20080153836A1,CCCC[Sn](CCCC)(CCCC)c1cc(C)nn1CCOC[Si](C)(C)C.COC(=O)c1cc(I)c(C(F)(F)F)cc1N>>COC(=O)c1cc(-c2cc(C)nn2CCOC[Si](C)(C)C)c(C(F)(F)F)cc1N,,C1COCCO1,,,,test
US20060257987A1,CCc1ccc(OCCC(CC)OS(C)(=O)=O)c(C(=O)c2ccccc2)c1.COC(=O)CCc1ccc(O)cc1C>>CCc1ccc(OCCC(CC)Oc2ccc(CCC(=O)OC)c(C)c2)c(C(=O)c2ccccc2)c1,,CCOCC,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150299188A1,COc1ccc(CCl)cc1.O=C1Nc2ccccc2CN1c1cc(OCc2ncccc2F)ccc1Br>>COc1ccc(CN2C(=O)N(c3cc(OCc4ncccc4F)ccc3Br)Cc3ccccc32)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20130252934A1,CCOC(=O)[C@H]1C[C@@H](NCc2ccccc2)CCO1>>OC[C@H]1C[C@@H](NCc2ccccc2)CCO1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US03996278,C=O.CC(C)(C)N.Oc1ccc(Br)cc1Br>>CC(C)(C)NCc1cc(Br)cc(Br)c1O,,C1COCCO1,,,,test
US20160075686A1,Brc1cncc(I)c1.CCC(=O)N1CC=CCC1>>CCC(=O)N1CCC(c2cncc(Br)c2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,CCN(CC)CC,O=CO,test
US20090192138A1,C1CNCCNC1.N#Cc1c(Cl)n(Cc2ccccc2)c2c(=O)n(Cc3nccc4ccccc34)cnc12>>Cl.N#Cc1c(N2CCCNCC2)n(Cc2ccccc2)c2c(=O)n(Cc3nccc4ccccc34)cnc12,,CC(=O)N(C)C,,,,test
US20140005132A1,C#Cc1ccccc1.CC(C)(C)[Si](O[C@H]1CC[C@@]2(C)C(=CCC3C2CC[C@@]2(C)C3CC[C@@H]2N=[N+]=[N-])C1)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](O[C@H]1CC[C@@]2(C)C(=CCC3C2CC[C@@]2(C)C3CC[C@@H]2n2cc(-c3ccccc3)nn2)C1)(c1ccccc1)c1ccccc1,,CN(C)C=O,O,O=C(CO)O[CH][C@@H](O)CO,C[O-].[Na+],test
US20040192767A1,CN(C)S(N)(=O)=O.COc1ccc(-c2ccc(OCc3cc(C(=O)O)oc3C)cc2)cc1>>COc1ccc(-c2ccc(OCc3cc(C(=O)NS(=O)(=O)N(C)C)oc3C)cc2)cc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20030073742A1,C=C(C)C(=O)Cl.CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O>>C=C(C)C(=O)O[C@@H]1C[C@H](C)CC[C@H]1C(C)C,,ClCCl,,CCN(CC)CC,,test
US05919811,C[Si](C)(C)N=C=O.NCc1ccc(N)cc1>>NC(=O)NCc1ccc(N)cc1,,C1CCOC1,,,,test
US20140288090A1,BrCc1ccccc1.COC(=O)c1ccc2[nH]nc(Br)c2c1>>COC(=O)c1ccc2c(c1)c(Br)nn2Cc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20110059943A1,CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(N)nc21.O=C(Cl)CCl>>CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(NC(=O)CCl)nc21,,ClCCl,,CCN(CC)CC,,test
US20050143597A1,CC#Cc1ccccc1.O=S(=O)(O)O>>CCC(=O)c1ccccc1,,CO,O,,,test
US20060111353A1,C1COCCO1.CCOC(=O)/C(=C/C1CCCCC1)c1ccc(Br)s1>>O=C(O)/C(=C\C1CCCCC1)C1=CC=C(Br)C1,,C1COCCO1,,CO,[Na+].[OH-],test
US20150094296A1,CC(C)(C)OC(=O)C(C)(C)Br.O=[N+]([O-])c1cn[nH]c1>>CC(C)(C)OC(=O)C(C)(C)n1cc([N+](=O)[O-])cn1,,CN(C)C=O,,O,,test
US20100311966A1,CCOC(=O)c1cccc2nc(N3CC(NC(=O)c4nc(Cl)c(CC)[nH]4)C3)sc12>>CCc1[nH]c(C(=O)NC2CN(c3nc4cccc(C(=O)O)c4s3)C2)nc1Cl,,CO,,O,[Li+].[OH-],test
US20130085148A1,Brc1nccs1.CC1(C)OB(c2cn[nH]c2)OC1(C)C>>c1csc(-c2cn[nH]c2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20070287709A1,N#Cc1ncc(F)cc1F.Nc1ccc(I)cc1F>>N#Cc1ncc(F)cc1Nc1ccc(I)cc1F,,C1CCOC1,CCOC(C)=O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20020137750A1,CCCCCCNCCO.O=[N+]([O-])c1cccc(CCl)c1>>CCCCCCN(CCO)Cc1cccc([N+](=O)[O-])c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140256756A1,CC(C)(C)OC(=O)N1CCC(N2CCC(Br)C2=O)CC1.Oc1ccc(Br)cc1F>>CC(C)(C)OC(=O)N1CCC(N2CCC(Oc3ccc(Br)cc3F)C2=O)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140288045A1,COC(=O)c1cc(I)c(Cl)cc1OC.OB(O)c1cc(Cl)ccc1Cl>>COC(=O)c1cc(-c2cc(Cl)ccc2Cl)c(Cl)cc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20140235591A1,CCCCCC[C@@H]1CCc2cc(C3CCC(=O)C3)ccc2C1.N.[C-]#N>>CCCCCC[C@@H]1CCc2cc(C3CCC(N)(C#N)C3)ccc2C1,,CO,ClCCl,[Cl-].[NH4+],,test
US20160009662A1,CC1(C)C(C(=O)O)C1(C)C>>CC1(C)C(CO)C1(C)C,,C1CCOC1,,,,test
US20020156081A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CC1=NN(c2ccc(Br)cc2)C(c2ccccc2)C1>>CC1=NN(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)C(c2ccccc2)C1,,CN(C)C=O,,ClCCl,CC(=O)[O-].[K+],test
US20040152690A1,Clc1cccnc1N1CCNCC1.FC(F)(F)c1ccc2nc(Cl)[nH]c2c1>>FC(F)(F)c1ccc2nc(N3CCN(c4ncccc4Cl)CC3)[nH]c2c1,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20120065233A1,COc1nccc(Cl)c1-c1nc2cc3c(cc2[nH]1)C(=O)N(C[C@@H](O)CO)C3=O>>O=C1c2cc3nc(-c4c(Cl)cc[nH]c4=O)[nH]c3cc2C(=O)N1C[C@@H](O)CO,,C1COCCO1,,Cl,,test
US20070142372A1,Brc1ccc2c(C3CCOC3)n[nH]c2c1.CCNC(=O)c1cc(F)c(C)c(B2OC(C)(C)C(C)(C)O2)c1>>CCNC(=O)c1cc(F)c(C)c(-c2ccc3c(C4CCOC4)n[nH]c3c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(C)O,,O=C([O-])O.[Na+],,test
US20060089398A1,Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)Nc1ccc(CCO)cc1>>Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)Nc1ccc(CC=O)cc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20090298826A1,CNCCN(C)C.COc1cc(O)ccc1-c1ccc2c(c1COC(=O)c1ccc(C)s1)C(C)=CC(C)(C)N2.O=C(n1ccnc1)n1ccnc1>>COc1cc(OC(=O)N(C)CCN(C)C)ccc1-c1ccc2c(c1COC(=O)c1ccc(C)s1)C(C)=CC(C)(C)N2,CN(C)c1ccncc1,C1CCOC1,,,,test
US20020183319A1,Cc1cc(C(=O)N2CCOCC2)[nH]c1C=O.O=C1Cc2c(ncnc2Nc2ccc(F)c(Cl)c2)N1>>Cc1cc(C(=O)N2CCOCC2)[nH]c1C=C1C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c21,C1CCNCC1,CCO,,,,test
US20080262033A1,C/C(N)=C\C#N.CCCC1CC(=O)CC(=O)C1.COCCNc1c(Br)cc(C=O)cc1S(=O)(=O)N1CCCC1>>CCCC1CC(=O)C2=C(C1)NC(C)=C(C#N)C2c1cc(Br)c(NCCOC)c(S(=O)(=O)N2CCCC2)c1,,CCO,,,,test
US20100016352A1,COCCl.COc1c(-c2ccc(Cl)cc2)oc2cc(O)cc(O)c2c1=O>>COCOc1cc(O)c2c(=O)c(OC)c(-c3ccc(Cl)cc3)oc2c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,Cl,test
US05554630,CC(=O)OC(C)=O.Nc1ccc(-c2ccccc2)cc1>>CC(=O)Nc1ccc(-c2ccccc2)cc1,,Cc1ccccc1,,,,test
US20130065897A1,CC1(C)OB(c2ccc3c(c2)COC3=O)OC1(C)C.CCO.O=Cc1ccc(Br)o1>>O=C1OCc2cc(-c3ccc(C4OCCO4)o3)ccc21,,Cc1ccccc1,,,,test
US20120040950A1,O=C1c2cccnc2C(=O)N1c1cnn(CC(F)(F)F)c1>>O=C1c2cccnc2C(O)N1c1cnn(CC(F)(F)F)c1,[Zn],CC(=O)O,,,,test
US20070173501A1,CC1(C)O/C(=C2/C(=O)Nc3cc(F)ccc32)C=C1Br.OB(O)c1ccc(F)nc1>>CC1(C)O/C(=C2/C(=O)Nc3cc(F)ccc32)C=C1c1ccc(F)nc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20070249607A1,O=C1CCC(=O)N1Br.OCc1cc(Cl)cc(C(F)(F)F)c1>>FC(F)(F)c1cc(Cl)cc(CBr)c1,,C1CCOC1,CCOC(C)=O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20040235932A1,CCOc1ccccc1OCCN(C(=O)OC(C)(C)C)[C@H](C)Cc1cc(C(N)=O)c2c(ccn2CCCOC(=O)C(C)(C)C)c1>>CCOc1ccccc1OCCN[C@H](C)Cc1cc(C(N)=O)c2c(ccn2CCCOC(=O)C(C)(C)C)c1,,CC(C)O,O,Cl,O=C([O-])O.[Na+],test
US03966801,CCOC(=O)C(O)CCc1ccc(C2CCCCC2)c(N)c1.CI>>CCOC(=O)C(O)CCc1ccc(C2CCCCC2)c(NC)c1,,c1ccncc1,,,,test
US20100190763A1,CI.O=C1Nc2cc(CN3CCN(c4ccc(Cl)cc4)CC3)cnc2N2CCNCC12>>CN1CCN2c3ncc(CN4CCN(c5ccc(Cl)cc5)CC4)cc3NC(=O)C2C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070105943A1,NCc1ccc(Oc2ccccc2)s1.O=C(O)c1cccnc1Cl>>O=C(NCc1ccc(Oc2ccccc2)s1)c1cccnc1Cl,,CN(C)C=O,O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20160108037A1,COC(=O)c1ccc(C(F)(F)F)nc1NN.S=C(n1ccnc1)n1ccnc1>>COC(=O)c1ccc(C(F)(F)F)n2c(=S)[nH]nc12,,CN(C)C=O,,,,test
US04304728,CCOC(=O)C(=O)CC(=O)CC(=O)c1cccc2ccccc12>>O=C(O)c1cc(=O)cc(-c2cccc3ccccc23)o1,,C1COCCO1,,Cl,,test
US20100272680A1,C[C@@H]1OC(=O)N(C2CCNCC2)C1=O.O=C(O)c1nc2c(C(F)(F)F)cc(Br)cn2c1Cl>>C[C@@H]1OC(=O)N(C2CCN(C(=O)c3nc4c(C(F)(F)F)cc(Br)cn4c3Cl)CC2)C1=O,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06313137B1,CCc1cccc(C)c1CNc1cc(C(=O)O)cn2c(C)c(C)nc12.CNC>>CCc1cccc(C)c1CNc1cc(C(=O)N(C)C)cn2c(C)c(C)nc12,,ClCCl,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,test
US20110184029A1,Cc1cc(Br)cc(CO)c1>>Cc1cc(Br)cc(C=O)c1,,CCOCC,ClCCl,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20090099182A1,O=C1C(N2CCC(F)(F)CC2)CCN1Cc1c(Cl)cc(OS(=O)(=O)C(F)(F)F)cc1Cl.OB(O)c1ccc(-c2ccccc2)cc1>>O=C1C(N2CCC(F)(F)CC2)CCN1Cc1c(Cl)cc(-c2ccc(-c3ccccc3)cc2)cc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],,test
US05935907,Cc1c(C(F)(F)F)n(C)c(=O)n(-c2cc([N+](=O)[O-])c(C#C[Si](C)(C)C)cc2F)c1=O>>Cc1c(C(F)(F)F)n(C)c(=O)n(-c2cc(N)c(C#C[Si](C)(C)C)cc2F)c1=O,[Fe],CCO,,CC(=O)O,O,test
US20070208003A1,CO.Nc1cccnc1C(=O)O>>COC(=O)c1ncccc1N,,CCOC(C)=O,CO,C[Si](C)(C)C=[N+]=[N-],,test
US05182283,CCCCCOc1nccnc1C1(O)CN2CCC1CC2.O=S(Cl)Cl>>CCCCCOc1nccnc1C1(Cl)CN2CCC1CC2,,ClCCl,,,,test
US05070207,C#CCO.CCCCCCCCCCCCCCCc1cccc(O)c1>>C#CCOc1cccc(CCCCCCCCCCCCCCC)c1,,CCCCCC,O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050038041A1,CSc1nc(C(F)(F)F)c(I)c(=O)[nH]1.O=P(Cl)(Cl)Cl>>CSc1nc(Cl)c(I)c(C(F)(F)F)n1,,O=P(Cl)(Cl)Cl,,ClP(Cl)(Cl)(Cl)Cl,,test
US20070299085A1,Cc1cc(Cn2cc(I)c(C(F)(F)F)n2)ccc1[N+](=O)[O-].FC(F)(F)C(F)(F)I>>Cc1cc(Cn2cc(C(F)(F)C(F)(F)F)c(C(F)(F)F)n2)ccc1[N+](=O)[O-],[Cu],CCOC(C)=O,,CN(C)C=O,,test
US20150051208A1,CC1CC(=O)NN=C1c1ccc2c(c1)nc(-c1cc([N+](=O)[O-])c(=O)n(C)c1)n2Cc1ccccc1>>CC1CC(=O)NN=C1c1ccc2c(c1)nc(-c1cc(N)c(=O)n(C)c1)n2Cc1ccccc1,[Ni],C1CCOC1,,,,test
US20090042876A1,C#Cc1ccc2[nH]c(=O)c3[nH]ccc3c2c1.C1COCCN1.C=O.CCC(=O)[O-]>>CCC(=O)[O-].O=c1[nH]c2ccc(C#CCN3CCOCC3)cc2c2cc[nH]c12,I[Cu]I,C1COCCO1,,CC(=O)O,,test
US20050245563A1,COC(=O)CCc1ccc2c(c1)c1nn(C3CCCCO3)c(C)c1c(=O)n2CCCNC(=O)OC(C)(C)C>>Cc1c2c(=O)n(CCCNC(=O)OC(C)(C)C)c3ccc(CCC(=O)O)cc3c2nn1C1CCCCO1,,C1CCOC1,O,Cl,[Na+].[OH-],test
US05424277,BrC1CCCC1.O=C1C2=C(CCCC2)C(=O)N1c1cc(O)c(Cl)cc1F>>O=C1C2=C(CCCC2)C(=O)N1c1cc(OC2CCCC2)c(Cl)cc1F,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US20090062277A1,COc1cc2nncc(-c3cnc(N4CCC(=O)CC4)c(C)c3)c2cc1OC.C[Mg]Br>>COc1cc2nncc(-c3cnc(N4CCC(C)(O)CC4)c(C)c3)c2cc1OC,,C1CCOC1,,,,test
US05061706,CCOC(=O)C(=O)Nc1ccc(Br)cc1[N+](=O)[O-]>>O=c1[nH]c2ccc(Br)cc2n(O)c1=O,[Ni],CN(C)C=O,,,,test
US20160038504A1,CNC.CS(=O)(=O)c1nc(Cl)cc(N2CCOCC2)n1>>CN(C)c1nc(Cl)cc(N2CCOCC2)n1,,C1COCCO1,,CCO,,test
US20130225600A1,Nc1ccc(Br)nc1.O=C(Cl)c1c(F)cccc1F>>O=C(Nc1ccc(Br)nc1)c1c(F)cccc1F,,ClCCl,,c1ccncc1,,test
US20070232645A1,O=[N+]([O-])c1cc(COc2ccccc2)ccc1Br.Oc1ccc(S)cc1>>O=[N+]([O-])c1cc(COc2ccccc2)ccc1Sc1ccc(O)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030232875A1,CCOC(=O)NC(=O)c1ccccc1C(N)=O.N[C@@H](Cc1ccc(F)cc1)C(=O)O>>O=C(O)C(Cc1ccc(F)cc1)N1C(=O)c2ccccc2C1=O,,CCOC(C)=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20130252951A1,CC(O)c1ccc(Cl)cc1.COC(=O)CC(C)=O>>COC(=O)C(C(C)=O)C(C)c1ccc(Cl)cc1,,ClCCl,,,,test
US20150299120A1,CCOC(=O)c1cnc(CN=[N+]=[N-])o1>>[N-]=[N+]=NCc1ncc(CO)o1,,CCO,,[BH4-].[Na+],,test
US20060194969A1,COCc1nc2c(N)cc(Br)cc2n1C.Cc1cccc(C)c1CCl>>COCc1nc2c(NCc3c(C)cccc3C)cc(Br)cc2n1C,,CC#N,O,[I-].[K+],,test
US20100249123A1,CC(C#N)c1cc([N+](=O)[O-])ccc1Cl.CI>>CC(C)(C#N)c1cc([N+](=O)[O-])ccc1Cl,,CN(C)C=O,,,,test
US20040053913A1,OCc1cc2n(n1)CCC2>>O=Cc1cc2n(n1)CCC2,O=[Mn]=O,ClC(Cl)Cl,,,,test
US20090149457A1,CCOC(=O)n1nc(NC(=O)c2ccccc2NC(=O)c2ccc[nH]2)c2cc(C(=O)OC(C)(C)C)sc21>>CCOC(=O)n1nc(NC(=O)c2ccccc2NC(=O)c2ccc[nH]2)c2cc(C(=O)O)sc21,,C1COCCO1,,Cl,,test
US05733913,CN1CCN(CCCNc2ncc3cc(-c4c(Cl)cccc4Cl)c(N)nc3n2)CC1.O=C=Nc1ccccc1>>CN1CCN(CCCNc2ncc3cc(-c4c(Cl)cccc4Cl)c(NC(=O)Nc4ccccc4)nc3n2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US04788195,Cc1ccc(S(=O)(=O)OCCCl)cc1.O=[N+]([O-])c1cccc(O)c1>>O=[N+]([O-])c1cccc(OCCCl)c1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06172228B2,Clc1ccc(C(c2ccc(Cl)cc2)N2CCNCC2)cc1.O=S(=O)(CCCCCCCl)NC1CC1>>O=S(=O)(CCCCCCN1CCN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CC1)NC1CC1,,CCN(C(C)C)C(C)C,,,,test
US20030144524A1,Cc1ccc(O)cc1.OC(O)C(F)(F)F>>Cc1ccc(O)c(C(O)C(F)(F)F)c1,,O,,[Na+].[OH-],,test
US20050222424A1,CCOC(=O)C(C)(C)Oc1ccc(CN(C)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1C>>Cc1cc(CN(C)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OC(C)(C)C(=O)O,,CCO,,[Na+].[OH-],,test
US20050282824A1,COC(=O)c1cc(C)nc(N2CCC(c3ccccc3)CC2)n1>>Cc1cc(C(=O)O)nc(N2CCC(c3ccccc3)CC2)n1,,C1CCOC1,,CO,[Li+].[OH-],test
US04742068,CC(C)(CC=O)CC=O.Cc1csc(N)n1>>Cc1csc(N2C=CC(C)(C)C=C2)n1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05952362,Cc1c([N+](=O)[O-])cc(NC(=O)OC(C)(C)C)cc1[N+](=O)[O-]>>Cc1c([N+](=O)[O-])cc(N)cc1[N+](=O)[O-],,O=C(O)C(F)(F)F,,,,test
US20050014754A1,N#Cc1ccc(CCC#Cc2nccs2)cc1>>Cc1cc(-c2ccc3sccn23)ccc1C#N,Cl[Cu],,,CC(=O)N(C)C,,test
US20070197526A1,COc1ccc(-n2nc(C(F)(F)F)cc2C=Cc2ccccc2)cc1>>Oc1ccc(-n2nc(C(F)(F)F)cc2C=Cc2ccccc2)cc1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20090137561A1,COc1ccc(F)c(-c2ccc(CO)cc2C2=C[C@H]3CC[C@]2(C)C3(C)C)c1.O=S(Cl)Cl>>COc1ccc(F)c(-c2ccc(CCl)cc2C2=C[C@H]3CC[C@]2(C)C3(C)C)c1,,CN(C)C=O,ClCCl,,,test
US05534529,BrCC1CCCCC1.CCCCCC.CSCS(=O)(=O)c1ccc(C)cc1>>CCCCCCCC(SC)S(=O)(=O)c1ccc(C)cc1,,CCCCCC,CN(C)C=O,[H-].[Na+],[Cl-].[NH4+],test
US20110124665A1,COC(=O)CNc1cccc(Oc2ncnc3oc(-c4ccccc4)c(-c4ccc(OC)cc4)c23)c1>>COc1ccc(-c2c(-c3ccccc3)oc3ncnc(Oc4cccc(NCC(=O)O)c4)c23)cc1,,C1COCCO1,,Cl,[Na+].[OH-],test
US04698093,CC(C)N.CCOC(=O)c1c(C(F)(F)F)nc(C(F)(F)Cl)c(C(=O)OC)c1Cl>>CCOC(=O)c1c(C(F)(F)F)nc(C(F)(F)Cl)c(C(=O)OC)c1NC(C)C,,CN(C)C=O,,,,test
US04810708,O=c1c2c(n(-c3ccccc3)c3ncccc13)-c1ccc(O)cc1CC2>>O=c1c2c(n(-c3ccccc3)c3c1CCc1cc(O)ccc1-3)NCCC2,[Pd],CCO,,[H][H],,test
US05508306,O=C(Cl)C(=O)Cl.O=C(O)C1CCc2ccccc2C1>>O=C(Cl)C1CCc2ccccc2C1,,Cc1ccccc1,,,,test
US20120129811A1,COc1ccc(C#N)cc1N.S=C(Cl)Cl>>COc1ccc(C#N)cc1N=C=S,,ClC(Cl)Cl,O,CCOC(C)=O,O=C([O-])O.[Na+],test
US20090082379A1,CC1(C)NC(=O)N(c2ccc(C(C)(C)C)cc2)C1=O.ClCc1ccnc(Cl)c1>>CC(C)(C)c1ccc(N2C(=O)N(Cc3ccnc(Cl)c3)C(C)(C)C2=O)cc1,,CN(C)C=O,O,[H-].[Na+],,test
US20090093474A1,CC(=O)Nc1nc2c(s1)C(=O)C(C(=O)C1CC1)CC2.COC(=O)c1ccc(NN)c(Cl)c1>>COC(=O)c1ccc(-n2nc(C3CC3)c3c2-c2sc(NC(C)=O)nc2CC3)c(Cl)c1,,CC(=O)O,,,,test
US20160168156A1,CC(C)(C)OC(=O)NN.CCC(=O)Cl>>CCC(=O)NNC(=O)OC(C)(C)C,,ClCCl,,,,test
US20080038195A1,CCCC[Sn](CCCC)(CCCC)c1cc(/C=C/c2ccc(N(C)C)cc2)cnc1OCCOCCOCCF.II>>CN(C)c1ccc(/C=C/c2cnc(OCCOCCOCCF)c(I)c2)cc1,,C1CCOC1,,ClCCl,,test
US20100056507A1,CC1(C)CCC(C)(C)c2cc(C(=O)OCCc3ccc([N+](=O)[O-])cc3)ccc21>>CC1(C)CCC(C)(C)c2cc(C(=O)OCCc3ccc(N)cc3)ccc21,[Pd],CCOC(C)=O,CO,,,test
US20140296232A1,C#CC(=O)Oc1cc(C)c(Br)c(C)c1.O=[N+]([O-])c1cccc(I)c1>>Cc1cc(OC(=O)C#Cc2cccc([N+](=O)[O-])c2)cc(C)c1Br,[Cu]I,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20030153566A1,COCCN(C)c1ccc(OC)c(NC(N)=S)c1>>COCCN(C)c1ccc(OC)c2nc(N)sc12,,ClC(Cl)Cl,,BrBr,,test
US20100305096A1,CC(C)(C)OC(=O)N1CC(=O)C1.CC1(O)CCNCC1>>CC1(O)CCN(C2CN(C(=O)OC(C)(C)C)C2)CC1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130338066A1,CC1(C)OC(N[C@@H](CCO)c2ccccc2)=NS(=O)(=O)C1c1ccc(O)cc1.CI>>COc1ccc(C2C(C)(C)OC(N[C@@H](CCO)c3ccccc3)=NS2(=O)=O)cc1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20150329523A1,COc1cc(N)cc(S(=O)(=O)C2CC2)c1.Cc1ccc(-n2nc(C(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c(Cl)c2Cl)cc1>>COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)C)nn4-c4ccc(C)cc4)c(Cl)c3Cl)n2)cc(S(=O)(=O)C2CC2)c1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20080269191A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1ccc2c(-c3ccc(I)cc3)noc2c1>>O=S(=O)(Oc1ccc2c(-c3ccc(I)cc3)noc2c1)C(F)(F)F,,ClCCl,O,c1ccncc1,,test
US20100234609A1,CCOC(CBr)OCC.Cc1ccc(N)cc1Br>>CCOC(CNc1ccc(C)c(Br)c1)OCC,,O,,CCN(CC)CC,CCO,test
US20060135773A1,CCOP(=O)(OCC)C(F)(F)c1ccc(CBr)cc1Br.CCOP(=O)(OCC)C(F)(F)c1ccc(CNS(=O)(=O)c2ccccc2)cc1>>CCOP(=O)(OCC)C(F)(F)c1ccc(CN(Cc2ccc(C(F)(F)P(=O)(OCC)OCC)c(Br)c2)S(=O)(=O)c2ccccc2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04493728,COCC(C)(C)C(=O)CC#N.NO>>COCC(C)(C)c1cc(N)no1,,CCO,O,Cl,[Na+].[OH-],test
US20030055244A1,CCOC(=O)COC1CCN(C(=O)N2CCC3(CCN(c4ccncc4)CC3)C2)CC1>>O=C(O)COC1CCN(C(=O)N2CCC3(CCN(c4ccncc4)CC3)C2)CC1,,C1COCCO1,,[Li+].[OH-],,test
US20150225381A1,CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=S)N1c1ccc(O)c(F)c1.Cc1ccc(S(=O)(=O)OC2CN(C(=O)OC(C)(C)C)C2)cc1>>CC(C)(C)OC(=O)N1CC(Oc2ccc(N3C(=S)N(c4ccc(C#N)c(C(F)(F)F)c4)C(=O)C3(C)C)cc2F)C1,,CC(=O)N(C)C,,O,O=C([O-])[O-].[K+].[K+],test
US20160075653A1,ON=C1CCC1c1ccccc1Cl>>NC1CCC1c1ccccc1Cl,,C1CCOC1,,B,,test
US20020091148A1,CCOC(=O)c1[nH]c2ccccc2c1-c1cccs1.NN>>NNC(=O)c1[nH]c2ccccc2c1-c1cccs1,,CCO,,O,,test
US20020156081A1,CN(Cc1ccccc1)c1ccccc1.O=C1C(Br)=CC(Br)(Br)C=C1Br>>CN(Cc1ccccc1)c1ccc(Br)cc1,,ClCCl,,,,test
US20060276655A1,O=C(NCC1(CC2CC2)CCC2(CC1)OCCO2)c1ccc(Cl)cc1Cl>>O=C1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(CC2CC2)CC1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20080167307A1,CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCN)cs1.CCCCCCCI.COC(=O)c1cnc(Cl)c(Cl)c1>>CCCCCCCN(CCc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1)c1ncc(C(=O)OC)cc1Cl,,CN(C)C=O,O,CC(C)(C)[O-].[K+],,test
US20060194788A1,CC(C)C1CCC(=O)C(Br)C1.NC(=S)N=C(N)N>>CC(C)C1CCc2nc(NC(=N)N)sc2C1,,CCO,,CCOC(C)=O,,test
US04732903,C[C@@H](OC(=O)[C@@H]1[C@H](C#CC(=O)OCC(Cl)(Cl)Cl)C1(C)C)c1cccc(Oc2ccccc2)c1>>C[C@@H](OC(=O)[C@@H]1[C@H](C#CC(=O)O)C1(C)C)c1cccc(Oc2ccccc2)c1,[Zn],ClCCl,,CC(=O)O,O,test
US20120252801A1,CCN1CC(C)(C)OC(=O)C1CC(=O)O.NCc1ccccc1Cl>>CCN1CC(C)(C)OC(=O)C1CC(=O)NCc1ccccc1Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060264415A1,Fc1ccc(S)cc1.O=C(O)C(F)(F)Cl>>O=C(O)C(F)(F)Sc1ccc(F)cc1,,C1COCCO1,,[H-].[Na+],,test
US20050256311A1,COCCN(C(C)(C)C)S(=O)(=O)c1ccc(I)cc1.Cc1ncc(-c2ccnc(N)n2)n1CC1CC1>>COCCN(C(C)(C)C)S(=O)(=O)c1ccc(Nc2nccc(-c3cnc(C)n3CC3CC3)n2)cc1,,O,,CC(=O)O,,test
US04112086,CCOC(C[PH](=O)OC(C)(C)C)(Sc1nnn[nH]1)C1=C(C(=O)OC(C)(C)C)N2C(=O)C(N)[C@H]2SC1.O=C(O)CS(=O)(=O)CC(F)(F)F>>CCOC(C[PH](=O)OC(C)(C)C)(Sc1nnn[nH]1)C1=C(C(=O)OC(C)(C)C)N2C(=O)[C@@H](NC(=O)CS(=O)(=O)CC(F)(F)F)[C@H]2SC1,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20050261291A1,CC1(C)CCC(c2ccccc2N2CCNCC2)CC1.O=Cc1ccoc1>>CC1(C)CCC(c2ccccc2N2CCN(Cc3ccoc3)CC2)CC1,,C1CCOC1,CCOC(C)=O,O=C([O-])O.[Na+],,test
US20120088741A1,FC1(F)Oc2ccc(CC3CCNC3)cc2O1.O=C(Nc1cccnc1)Oc1ccccc1>>O=C(Nc1cccnc1)N1CCC(Cc2ccc3c(c2)OC(F)(F)O3)C1,,CC#N,,CCN(CC)CC,,test
US20090163471A1,CC(=O)Nc1ccc(C(=O)O)c(C)c1.O=[N+]([O-])O>>Cc1c(C(=O)O)ccc(N)c1[N+](=O)[O-],,O,O=S(=O)(O)O,,,test
US20160115119A1,CC(=O)Oc1ccccc1C(=O)O.N[C@@H]1CCc2c(F)cc(Cl)cc21.O=Cc1cccnc1.[C-]#[N+]C1=CCC(c2ccccc2)CC1>>NC(=O)[C@@H](c1cccnc1)N(C(=O)c1ccccc1O)[C@@H]1CCc2c(F)cc(Cl)cc21,,CCN(CC)CC,,CO,Cl,test
US20130338142A1,O=[N+]([O-])c1ccc(F)cc1.OCCC1CNCCO1>>O=[N+]([O-])c1ccc(N2CCOC(CCO)C2)cc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20090227591A1,COc1ccc(C(F)(F)F)cc1C1=C(c2cccc(C(=O)O)n2)CCC1>>O=C(O)c1cccc(C2=C(c3cc(C(F)(F)F)ccc3O)CCC2)n1,,ClCCl,,BrB(Br)Br,,test
US20090137557A1,COCc1nc(-c2ccccc2OCc2ccccc2)n(CCc2ccccc2)c(=O)c1Br.OB(O)c1ccc2c(c1)OCCO2>>COCc1nc(-c2ccccc2OCc2ccccc2)n(CCc2ccccc2)c(=O)c1-c1ccc2c(c1)OCCO2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCO,O=C([O-])[O-].[Na+].[Na+],,test
US20110118245A1,CC(C)c1cc(NC(=O)Oc2ccccc2)n(-c2ccccc2)n1.COc1cc2ncnc(Sc3cccc(N)c3)c2cc1OC>>COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(C(C)C)nn4-c4ccccc4)c3)c2cc1OC,CN(C)c1ccncc1,C1CCOC1,,,,test
US20060247179A1,COC(=O)CBr.COc1cccc(S)c1C(=O)C=CC1C=CC=CC1>>COC(=O)c1sc2cccc(OC)c2c1CCc1ccccc1,,ClCCl,,CCN(CC)CC,O,test
US20040024052A1,C/C(=C\C(=O)OCCCCCCCCC(=O)[O-])C[C@@H]1OC[C@H](C[C@@H]2O[C@H]2[C@@H](C)[C@H](C)O)[C@@H](O)[C@H]1O.C/C(=C\C(=O)OCCCCCCCCC(=O)[O-])C[C@@H]1OC[C@H](C[C@@H]2O[C@H]2[C@@H](C)[C@H](C)O)[C@@H](O)[C@H]1O.CO.O.[Ca+2]>>C/C(=C\C(=O)OCCCCCCCCC(=O)[O-])C[C@@H]1OC[C@H](C[C@@H]2O[C@H]2[C@@H](C)[C@H](C)O)[C@@H](O)[C@H]1O.C/C(=C\C(=O)OCCCCCCCCC(=O)[O-])C[C@@H]1OC[C@H](C[C@@H]2O[C@H]2[C@@H](C)[C@H](C)O)[C@@H](O)[C@H]1O.O.O.[Ca+2],,CO,,,,test
US20060235029A1,CCCN.CCN(CC)CCCNc1nc(-c2cccc(C(=O)O)c2)c2ccc(=O)n(-c3c(F)cccc3F)c2n1>>CCCNC(=O)c1ccccc1-c1nc(NCCCN(CC)CC)nc2c1ccc(=O)n2-c1c(F)cccc1F,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160115158A1,COc1cc(Cl)nnc1NS(=O)(=O)Cc1ccc(C#N)cc1>>N#Cc1ccc(CS(=O)(=O)Nc2nnc(Cl)cc2O)cc1,,ClCCl,,BrB(Br)Br,,test
US20100075976A1,COCc1ccc(-c2nccnc2N2CCN(CCN(C)S(=O)(=O)c3cnn(C)c3)CC2)cc1.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>COCc1ccc(-c2nccnc2N2CCN(CCN(C)S(=O)(=O)c3cnn(C)c3)CC2)cc1.O=C(O)[C@H](O)[C@@H](O)C(=O)O,,CCO,,,,test
US20140309213A1,Cc1c([C@@H](O)CN2CCN(C(=O)OC(C)(C)C)C3(CCCC3)C2)ccc2c1COC2=O.Cl>>Cc1c([C@@H](O)CN2CC[NH2+]C3(CCCC3)C2)ccc2c1COC2=O.[Cl-],,C1COCCO1,,,,test
US20140148453A1,FCCBr.O=[N+]([O-])c1ccc(Br)c(O)c1>>O=[N+]([O-])c1ccc(Br)c(OCCF)c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20120040998A1,CC1CCC(C(N)=O)CN1C(=O)OC(C)(C)C.O=C(COS(=O)(=O)c1ccc([N+](=O)[O-])cc1[N+](=O)[O-])c1ccc(F)cn1>>C[C@@H]1CC[C@H](c2nc(-c3ccc(F)cn3)co2)CN1C(=O)OC(C)(C)C,,CC#N,,,,test
US20140288045A1,COc1cc(Cl)c(-c2ccccc2Cl)cc1C(=O)N1CCN(C(=O)/C=C/CN(C)C)CC1>>CN(C)C/C=C/C(=O)N1CCN(C(=O)c2cc(-c3ccccc3Cl)c(Cl)cc2O)CC1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20060199833A1,COc1ccc(N(C(=O)c2c3ccccc3nc3occc23)S(=O)(=O)CCCC(=O)OC(C)(C)C)cc1>>COc1ccc(N(C(=O)c2c3ccccc3nc3occc23)S(=O)(=O)CCCC(=O)O)cc1,,O=C(O)C(F)(F)F,,,,test
US03994900,CN(C)CCCOc1ccc2c(c1)C(c1ccccc1)CC(=O)N2.Cl>>CN(C)CCCOc1ccc2c(c1)C(c1ccccc1)CC(=O)N2.Cl,,CCO,,CCOCC,,test
US20080058549A1,CCCCCCCCCC.CCCCCCO>>CCCCCCCCCCO,,CCCCCC,,C1CCC2=NCCCN2CC1,,test
US05059611,C[Si](C)(C)c1cc(CCC=O)co1.O=CC=P(c1ccccc1)(c1ccccc1)c1ccccc1>>C[Si](C)(C)c1cc(CCC=CC=O)co1,,C1CCOC1,,,,test
US20050203296A1,C=O.Cc1ccc2c(c1)Nc1ccccc1N=C2N1CCN[C@@H](CCc2ccccc2)C1>>Cc1ccc2c(c1)Nc1ccccc1N=C2N1CCN(C)[C@@H](CCc2ccccc2)C1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05994536,C1CNCCNCCNCCN1.CC1(C)OCC2OC2CO1.[Cl-].[Li+]>>CC1(C)OCC(O)C(N2CCNCCNCCNCC2)CO1.[Cl-].[Li+],,CC(C)O,,,,test
US04495195,COC(=O)c1c(Br)c(-c2cccc(C(F)(F)F)c2)nn1C>>Cn1nc(-c2cccc(C(F)(F)F)c2)c(Br)c1C(=O)O,,CCO,,[Na+].[OH-],,test
US20050250775A1,CC(C)(C)OC(=O)N1CCO[C@H]([C@H](O)c2ccccn2)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCO[C@H]([C@H](OS(C)(=O)=O)c2ccccn2)C1,,ClCCl,O,CCN(CC)CC,O=C([O-])O.[Na+],test
US05753677,CN.Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(COS(C)(=O)=O)c3ccccc32)cc1>>CNCC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc21,,CO,,,,test
US20100048849A1,CCCCCC1CCC(C(=O)O)CC1.O=C(/C=C/c1ccc(O)cc1)OCCCCCCOC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>CCCCCC1CCC(C(=O)Oc2ccc(/C=C/C(=O)OCCCCCCOC(=O)c3cc([N+](=O)[O-])cc([N+](=O)[O-])c3)cc2)CC1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US04766233,CC(C)Oc1cc(-n2ncc(=O)[nH]c2=O)c(Cl)cc1Cl.CI>>CC(C)Oc1cc(-n2ncc(=O)n(C)c2=O)c(Cl)cc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20100102299A1,CCCCCCCCCCCCCCCCBr.c1ccsc1>>CCCCCCCCCCCCCCCCc1cccs1,,C1CCOC1,ClCCl,O,[Li]CCCC,test
US20060089371A1,N#Cc1ccnc(Oc2ccc(-c3cc(N[C@@H](Cc4ccccc4)C(=O)[O-])ncn3)cc2)c1>>N#Cc1ccnc(Oc2ccc(-c3cc(N[C@@H](Cc4ccccc4)C(=O)O)ncn3)cc2)c1,,C1CCOC1,,Cl,[Li+].[OH-],test
US05106835,CC(C)C[C@@H](C=O)NC(=O)OC(C)(C)C.C[Si](C)(C)c1nccs1>>CC(C)C[C@H](NC(=O)OC(C)(C)C)[C@H](O)c1nccs1,,C1CCOC1,ClCCl,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20060089382A1,C#CCOC.COc1cc2ncc(C#N)c(Nc3c(Cl)cc(I)c4c3OCO4)c2cc1OC>>COCC#Cc1cc(Cl)c(Nc2c(C#N)cnc3cc(OC)c(OC)cc23)c2c1OCO2,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,,CC(C)NC(C)C,,test
US03952041,C=Cc1ccccc1.c1ccccc1>>C=CC=C.C=Cc1ccccc1,,c1ccccc1,,,,test
US20160198713A1,N#CC1CCNCC1.O=C(Cl)CC(=O)OCc1ccccc1>>N#CC1CCN(C(=O)CC(=O)OCc2ccccc2)CC1,,ClCCl,,CCN(CC)CC,O,test
US06375943B1,CCCCCC.CCOC(C)=O>>C[C@@H]1CC=CC[C@H]1C(=O)O,,ClC(Cl)Cl,,Cl,,test
US04159344,Nc1cccc(NC(=O)C(F)(F)C(F)(F)F)c1.O=C(Cl)Cl>>O=C=Nc1cccc(NC(=O)C(F)(F)C(F)(F)F)c1,,C1CCOC1,,CCN(CC)CC,,test
US20140187556A1,Nc1cc(N2CCN(C(=O)c3ccccc3)CC2)ccc1-n1cnnn1.O=Cc1ccccc1>>O=C(c1ccccc1)N1CCN(c2ccc(-n3cnnn3)c(NCc3ccccc3)c2)CC1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20040162276A1,Cc1ccc(S(=O)(=O)n2nc(N)c3c2CC(c2ccccc2)(c2ccccc2)C=C3)cc1>>Nc1n[nH]c2c1C=CC(c1ccccc1)(c1ccccc1)C2,,C1CCOC1,,C1COCCO1,[Na+].[OH-],test
US20060148858A1,O=C1CCC(C(F)(F)F)=NN1>>O=c1ccc(C(F)(F)F)n[nH]1,,CC(=O)O,,BrBr,,test
US20090197871A1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1ccc(C(=O)O)cc1.C[C@H]1CN(Cc2cccc(-c3cc(CN)ccc3F)c2)CCN1C(=O)OC(C)(C)C>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1ccc(C(=O)NCc2ccc(F)c(-c3cccc(CN4CCN[C@@H](C)C4)c3)c2)cc1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06632816B1,CC(C)CN([C@H](CO)CCCCNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)OC(C)(C)C)S(=O)(=O)c1ccc(N)cc1>>CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](N)Cc1ccc2ccccc2c1)S(=O)(=O)c1ccc(N)cc1,,CCO,,Cl,,test
US20060128724A1,CC(Oc1cc(-c2cnn(CC3(O)CCN(C(=O)OC(C)(C)C)CC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl>>CC(Oc1cc(-c2cnn(CC3(O)CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl,,ClCCl,,C1COCCO1,Cl,test
US04931455,CCc1cc(NC(CC)CCCCCCOC(=O)Cl)nc(Cl)n1.COc1cc(CNCCCNCCCCNCCCN)ccc1O.c1c[nH]cn1>>CCc1cc(NC(CC)CCCCCCOC(=O)n2ccnc2)nc(Cl)n1.COc1cc(CNCCCNCCCCNCCCN)ccc1O,,Cc1ccccc1,,CCN(CC)CC,,test
US20060089393A1,CC(C)(C)C(=O)NNC(=O)c1ccc(Br)cc1.CC(C)O.Cc1c(F)cc(C(=O)NC2CC2)cc1B1OC(C)(C)C(C)(C)O1>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NNC(=O)OC(C)(C)C)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(C)O,CCOC(C)=O,O=C([O-])O.[Na+],,test
US04239901,Clc1cnn(-c2ccc(CBr)c(Cl)c2)c1.[C-]#N>>N#CCc1ccc(-n2cc(Cl)cn2)cc1Cl,,CS(C)=O,,O,,test
US06150533,Nc1c(OCCN(CCCc2c[nH]c3ccccc23)C(=O)C(F)(F)F)cccc1[N+](=O)[O-]>>Nc1cccc(OCCN(CCCc2c[nH]c3ccccc23)C(=O)C(F)(F)F)c1N,[Pd],CCO,,,,test
US20150045349A1,CC(C)C(C)n1ccc(Cl)c(C#N)c1=O.O=C1CCC(=O)N1Br>>CC(C)C(C)n1cc(Br)c(Cl)c(C#N)c1=O,,CN(C)C=O,,O,,test
US20110300074A1,CN(C)c1cccc(N)c1.CS(=O)(=O)Cl>>CN(C)c1cccc(NS(C)(=O)=O)c1,,O,,[Na+].[OH-],,test
US04140687,COC1=CC=C2[C@H]3Cc4ccc(OC)c5c4[C@@]2(CCN3C)[C@H]1O5>>COc1ccc2c3c1O[C@H]1[C@@H](O)C=C[C@H]4[C@@H](C2)N(C)CC[C@@]341,,CC(=O)O,,Br,,test
US20150018363A1,Cc1c(C2CC2)nc2ccc(-n3ccc(Br)cc3=O)cn12.OCc1ccc(C(F)(F)F)o1>>Cc1c(C2CC2)nc2ccc(-n3ccc(OCc4ccc(C(F)(F)F)o4)cc3=O)cn12,,Cc1ccccc1,,CC(C)(C)[O-].[K+],,test
US20110021522A1,COc1cccc2cc(C(=O)O)c(=O)oc12.Nc1cccc(-c2ccc3c(c2)OCO3)c1>>COc1cccc2cc(C(=O)Nc3cccc(-c4ccc5c(c4)OCO5)c3)c(=O)oc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050282842A1,CSc1nccc(-c2c(CC(C)C)nn3ccccc23)n1.O=C(OO)c1cccc(Cl)c1>>CC(C)Cc1nn2ccccc2c1-c1ccnc(S(C)=O)n1,,ClCCl,,O=C([O-])O.[Na+],,test
US20060106225A1,C1COCCN1.O=C(NOCC1CC1)c1cc2c(ncn2CCCCCl)c(F)c1Nc1ccc(I)cc1Cl>>O=C(NOCC1CC1)c1cc2c(ncn2CCCCN2CCOCC2)c(F)c1Nc1ccc(I)cc1Cl,,CN(C)C=O,,[I-].[Na+],,test
US20120015962A1,CN(C)C=O.O.O=C(O)c1csc2cnc(Cl)nc12.c1ccc2c(c1)nnn2OC(N1CCCC1)=[N+]1CCCC1>>COc1ccc(NC(=O)c2csc3cnc(Cl)nc23)c(OC)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040210081A1,Cc1ccc(S(=O)(=O)O)cc1.Cc1ccccc1.O=C(O)CCC(=O)O.OCC1CC2CCC1C2>>O=C(CCC(=O)OCC1CC2CCC1C2)OCC1CC2CCC1C2,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,,,test
US04489093,C=CCC1=C(C)[C@@H](O)CC1=O.COC(=O)/C(Cl)=C/[C@H]1[C@@H](C(=O)Cl)C1(C)C>>C=CCC1=C(C)C(OC(=O)[C@@H]2[C@H](/C=C(\Cl)C(=O)OC)C2(C)C)CC1=O,,c1ccccc1,,,,test
US20120046278A1,C1CNCCN1.CS(=O)(=O)c1nc(N)nc2sc(-c3ccc(F)cc3)nc12>>Nc1nc(N2CCNCC2)c2nc(-c3ccc(F)cc3)sc2n1,,C1COCCO1,,CCN(CC)CC,,test
US20140005168A1,Cc1cncc(-c2cc3c(cn2)cnn3-c2cccc(C3CN(C(=O)OC(C)(C)C)CCC3=O)n2)n1>>Cc1cncc(-c2cc3c(cn2)cnn3-c2cccc(C3CN(C(=O)OC(C)(C)C)CCC3O)n2)n1,,C1CCOC1,,[BH4-].[Na+],,test
US20110245249A1,Clc1ncc(Cl)c(NC2CC2)n1.Nc1cccc(C2OCCCO2)c1>>Clc1cnc(Nc2cccc(C3OCCCO3)c2)nc1NC1CC1,,C1COCCO1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US06391991B1,CC(C)(C)C1Cc2ccccc2C1O>>CC(C)(C)C1=Cc2ccccc2C1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US06174884B1,CC(CCCc1ccccc1)n1ncc(C#N)c1N.OO>>CC(CCCc1ccccc1)n1ncc(C(N)=O)c1N,,CCO,,N,,test
US05942511,C=CCS.CCCOc1ccc(Cl)nn1>>C=CCSc1ccc(OCCC)nn1,,CO,,[Na],,test
US20090137623A1,BrC1C2CCC1N(Cc1ccccc1)C2.CC(C(=O)O)(c1ccccc1)c1ccccc1>>CC(C(=O)OC1C2CCC1N(Cc1ccccc1)C2)(c1ccccc1)c1ccccc1,,Cc1ccccc1,,C1CCC2=NCCCN2CC1,,test
US20100267666A1,CC(C)(C)C(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3cc(O)cc(N4CCCC4)c3)nc12.CSCCO>>CSCCOc1cc(-c2cnc3c(n2)c(C(=O)C(C)(C)C)cn3COCC[Si](C)(C)C)cc(N2CCCC2)c1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080255128A1,CC1C(=O)N(c2cc(Cc3n[nH]c(=O)c4ccccc34)ccc2F)C(=O)N1CCN1CCCC1.Cl>>CC1C(=O)N(c2cc(Cc3n[nH]c(=O)c4ccccc34)ccc2F)C(=O)N1CCN1CCCC1.Cl,,CO,,,,test
US20060183736A1,CC(C)COC(=O)Cl.CS(=O)(=O)c1ccc(-c2ccc3cc(O)ccc3c2Oc2ccc(OCCN3CCCCC3)cc2)cc1>>CC(C)COC(=O)Oc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(S(C)(=O)=O)cc3)ccc2c1,,ClCCl,,CCOCC,,test
US20050272665A1,CC(=O)Cl.CO.COC(OC)OC.C[C@@H](C=O)N(C)C(=O)OC(C)(C)C>>CN[C@@H](C)C(OC)OC.Cl,,CO,,,,test
US07169926B1,CCn1ccc(N)c([N+](=O)[O-])c1=O>>CCn1ccc(N)c(N)c1=O,[Pd],C1CCOC1,CCO,,,test
US20030212276A1,CNCCCN(C)C.COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(C#N)cnc2cc1F>>COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(C#N)cnc2cc1N(C)CCCN(C)C,,CN1CCCC1=O,,,,test
US03989841,COc1ccc2c(c1)Cc1c-2ccc(CC(=O)O)c1C>>COc1ccc2c(c1)Cc1cc(CC(=O)O)ccc1-2,,CCO,,[K+].[OH-],,test
US20110136764A1,CCOP(=O)(Cc1cnc([N+](=O)[O-])c(OC)c1)OCC>>CCOP(=O)(Cc1cnc(N)c(OC)c1)OCC,[Pd],CO,,,,test
US09181279B2,CCN(CC)S(F)(F)F.O=C(OCc1cccc(C(F)(F)F)c1)[C@H]1C[C@@H](O)CN1Cc1cccc(C(F)(F)F)c1>>O=C(OCc1cccc(C(F)(F)F)c1)C1CC(F)CN1Cc1cccc(C(F)(F)F)c1,,ClCCl,,,,test
US20020103229A1,COC(=O)c1ccc(NC(=O)c2ccc3[nH]nc(-c4ccc(F)cc4)c3c2)cc1>>O=C(O)c1ccc(NC(=O)c2ccc3[nH]nc(-c4ccc(F)cc4)c3c2)cc1,,CO,O,[Na+].[OH-],,test
US20160002169A1,CC(C)(C)[Si](OC[C@@H]1C[C@H]1CO)(c1ccccc1)c1ccccc1.CS(=O)(=O)Cl>>CC(C)(C)[Si](OC[C@@H]1C[C@H]1COS(C)(=O)=O)(c1ccccc1)c1ccccc1,,O,,C1CCOC1,,test
US20140142083A1,COC(=O)c1cc(C(F)(F)F)cc(N)c1C.O=C1CCCC1>>COC(=O)c1cc(C(F)(F)F)cc(NC2CCCC2)c1C,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20130157995A1,CN1C(=O)CC[C@H]1CO.Oc1cccnc1>>CN1C(=O)CC[C@H]1COc1cccnc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100160369A1,CC(C)Oc1cnc(N)c(Cl)c1.CCOC(=O)C(=O)CBr>>CC(C)Oc1cc(Cl)c2nc(C(=O)O)cn2c1,,CCO,,O,[Na+].[OH-],test
US04052412,COC(=O)CCC(=O)c1cc2c(s1)CCc1ccccc1C2=O>>O=C(O)CCC(=O)c1cc2c(s1)CCc1ccccc1C2=O,,C1COCCO1,O,Cl,[K+].[OH-],test
US20020132796A1,CC(C)=CC(=O)Cl.CNc1ccc(Br)cc1>>CC(C)=CC(=O)N(C)c1ccc(Br)cc1,,ClCCl,,CCN(CC)CC,,test
US20130052281A1,FC(F)(F)c1cncc(C#Cc2cc(OCc3ccccc3)c(OCc3ccccc3)nn2)c1>>FC(F)(F)c1cncc(CCc2cc(OCc3ccccc3)c(OCc3ccccc3)nn2)c1,[Pd],CO,,,,test
US20080004302A1,CI.O=C(O)CCc1cccc(O)c1>>COC(=O)CCc1cccc(O)c1,,CN(C)C=O,,O=C([O-])O.[K+],,test
US20150307483A1,CC(=O)c1cccc([N+](=O)[O-])c1O.CI>>COc1c(C(C)=O)cccc1[N+](=O)[O-],,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US06207662B1,CCCCOB(OCCCC)OCCCC.COc1ccc(Cl)cc1Br>>COc1ccc(Cl)cc1B(O)O,,C1CCOC1,CCOCC,Cl,[Li]CCCC,test
US20030125317A1,COC(=O)CC1Cc2ccc(OCCCNc3ccccn3)cc2CN(CC(F)(F)F)C1=O>>O=C(O)CC1Cc2ccc(OCCCNc3ccccn3)cc2CN(CC(F)(F)F)C1=O,,C1CCOC1,O,[Li+].[OH-],,test
US20130040934A1,CC(C)(C)OC(=O)N1CC2(CNC2)C1.FC(F)c1nc2ccccc2n1-c1nc(Cl)nc(N2CCOCC2)n1>>CC(C)(C)OC(=O)N1CC2(C1)CN(c1nc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n1)C2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04322357,CC(C)(C)[Si](C)(C)Cl.CC1CCC(O)CCC1=O>>CC1CCC(O[Si](C)(C)C(C)(C)C)CCC1=O,,CCOCC,CN(C)C=O,c1c[nH]cn1,,test
US20070232583A1,Clc1ccnc(Cl)n1.OB(O)c1ccc(Cl)cc1>>Clc1ccc(-c2ccnc(Cl)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US04588821,CC(=CCBr)CBr.COC(=O)CC#N>>C=C(C)C1CC1(C#N)C(=O)OC,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20030216432A1,COc1cc(NC(=O)C(C)C)c(Br)cc1C.COc1ccc(CCl)cc1>>COc1ccc(CN(C(=O)C(C)C)c2cc(OC)c(C)cc2Br)cc1,,CS(C)=O,,O,[K+].[OH-],test
US04029774,Cc1cccc(O)c1.ClSc1ccccc1.Oc1ccccc1>>Cc1cc(S)ccc1-c1ccccc1,,ClC(Cl)(Cl)Cl,,,,test
US05302593,CN1CCNCC1CCCCCCCCc1cccc2c1C(=O)NC2=O.NN>>CN1CCNCC1CCCCCCCCN,,CO,,,,test
US20120110702A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1nn(-c2cncc(F)c2)cc1[N+](=O)[O-]>>Cc1nn(-c2cncc(F)c2)cc1NC(=O)OC(C)(C)C,[Pd],CCO,O,CCOC(C)=O,O=C([O-])O.[Na+],test
US20130184253A1,COc1nc(-c2cccc3c2c(C)cn3S(=O)(=O)c2ccc(C)cc2)nc2c1CN(c1cc(C(C)C)nn1C)CC2>>Cc1ccc(S(=O)(=O)n2cc(C)c3c(-c4nc(O)c5c(n4)CCN(c4cc(C(C)C)nn4C)C5)cccc32)cc1,,CCO,,Cl,O=C([O-])O.[Na+],test
US04558134,CCCSc1ccc(Cl)c(C#N)n1.Oc1ccc(Cl)c(Cl)c1>>CCCSc1ccc(Oc2ccc(Cl)c(Cl)c2)c(C#N)n1,,C1CCOC1,CS(C)=O,CC(C)(C)[O-].[K+],,test
US20150210722A1,CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)n(-c2cccc(CP(C)(C)=O)c2)n1.COCCOCCOCCOCCOCCOc1cc(N)cc(OC)c1>>COCCOCCOCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)C)nn4-c4cccc(CP(C)(C)=O)c4)c4ccccc34)n2)cc(OC)c1,,CCOCC,CN(C)C=O,O=C([O-])O.[Na+],,test
US20140038990A1,CN.COC(=O)c1nc(CC2CCCCC2)[nH]c(=O)c1O>>CNC(=O)c1nc(CC2CCCCC2)[nH]c(=O)c1O,,CO,,,,test
US20100216814A1,CC(=CBr)c1ccc(C(=O)N(C)C)cc1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>Cc1ccc2c(c1)c1c(n2C2(C(=O)N(C)C)C=CC=CC2)CCN(C)C1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20140140956A1,BrP(Br)Br.COc1ccc2c(=O)[nH]c(-c3ccc(OCCO)c(-c4ccc(S(C)(=O)=O)cc4)n3)nc2c1>>COc1ccc2c(=O)[nH]c(-c3ccc(OCCBr)c(-c4ccc(S(C)(=O)=O)cc4)n3)nc2c1,,CN(C)C=O,,,,test
US05212324,CCCCC(F)(F)C(=O)CC[C@H]1[C@H](OC2CCCCO2)C[C@@H]2OC(=O)C[C@@H]21>>O=C1CC2CCCC2O1,,CO,,[BH4-].[Na+],,test
US20150038488A1,C[C@@H](Oc1cc(-c2ccc3c(c2)N(C(=O)OC(C)(C)C)CCN3C)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1>>C[C@@H](Oc1cc(-c2ccc3c(c2)NCCN3C)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070185111A1,Cc1csc(-c2nnc(Nc3ccc(Oc4ncccc4-c4ccnc(N)n4)cc3)c3ccccc23)n1.O=P(OCc1ccccc1)(OCc1ccccc1)OP(=O)(OCc1ccccc1)OCc1ccccc1>>Cc1csc(-c2nnc(Nc3ccc(Oc4ncccc4-c4ccnc(NP(=O)(OCc5ccccc5)OCc5ccccc5)n4)cc3)c3ccccc23)n1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20030092694A1,BrCCOc1ccccc1.Oc1cccnc1Cl>>Clc1ncccc1OCCOc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060217372A1,CC(C)CCCN.COc1cc(C=O)ccc1Oc1cnc(C(N)=O)cn1>>COc1cc(CNCCCC(C)C)ccc1Oc1cnc(C(N)=O)cn1,,CO,,[BH4-].[Na+],,test
US20020169173A1,N#CN.O=C(OC(C(=O)c1ccc(F)cc1)c1ccncc1)c1ccccc1>>Nc1nc(-c2ccc(F)cc2)c(-c2ccncc2)o1,,CCO,,[K+].[OH-],,test
US20160172678A1,C=CCCCC.C=COC(C)=O>>C=CCCCC.C=COC(C)=O,,CO,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20070129334A1,CC(=O)OCCCn1c(Sc2ccc3c(c2)OCO3)nc2c(N)ncnc21>>Nc1ncnc2c1nc(Sc1ccc3c(c1)OCO3)n2CCCO,,C1CCOC1,CO,O=C([O-])[O-].[K+].[K+],,test
US05274116,C[C@H](NC(=O)OCc1ccccc1)C(=O)O.Nn1cccc1>>C[C@H](NC(=O)OCc1ccccc1)C(=O)Nn1cccc1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20160251348A1,Cc1nccnc1Cl.O=C1CCC(=O)N1Br>>Clc1nccnc1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US06218431B1,CCCC=Cc1c(C(C)C)nc(C(C)C)c(C(=O)OCC)c1-c1ccc(Cl)cc1Cl>>CCCC=Cc1c(C(C)C)nc(C(C)C)c(CO)c1-c1ccc(Cl)cc1Cl,,CCCCCC,CCOC(C)=O,,,test
US20050222197A1,CCOc1ccc2nccc(C)c2c1.CON(C)C(=O)c1cccc(C)n1>>CCOc1ccc2nccc(CC(=O)c3cccc(C)n3)c2c1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US05286740,CC(CC(F)(F)F)C(=O)O.C[C@H](N)c1ccccc1>>CC(CC(F)(F)F)C(=O)N[C@@H](C)c1ccccc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20080207634A1,CCOC(C)=O.CN(Cc1cn2c(F)cccc2n1)[C@H]1CCOc2cccnc21.CN1CCCC1=O.NC1CCNC1>>CN(Cc1cn2c(N3CCC(N)C3)cccc2n1)[C@H]1CCOc2cccnc21.[NH4+].[OH-],,CCOC(C)=O,CN1CCCC1=O,,,test
US20110112151A1,CC(C)(C(=O)CBr)c1ccc(Cl)cc1.Cn1cnnc1S>>Cn1cnnc1SCC(=O)C(C)(C)c1ccc(Cl)cc1,,CC#N,ClCCl,CCN(CC)CC,,test
US20140011845A1,COC(=O)C(CC1CCN(OC)CC1)NC(=O)Cc1cc(C)ccc1C>>CON1CCC(CC2NC(=O)C(c3cc(C)ccc3C)=C2O)CC1,,C1CCOC1,,Cl,CC(C)(C)[O-].[K+],test
US20080009524A1,Brc1cccc(-c2nnn[nH]2)c1.Cc1ccc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)cc1B1OC(C)(C)C(C)(C)O1>>Cc1ccc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)cc1-c1cccc(-c2nn[nH]n2)c1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20140107194A1,NCCO.O=C(O)c1ccc(C[C@@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@H]2O)cc1>>O=C(NCCO)c1ccc(C[C@@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@H]2O)cc1,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US20130053365A1,O=C1CCC(=O)N1Br.O=C1OCc2c(F)cc(F)cc21>>O=C1OC(Br)c2c(F)cc(F)cc21,,ClC(Cl)(Cl)Cl,,O,,test
US20120157479A1,C=CCN(CC=C)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC=CC1,,ClCCl,,,,test
US20110021351A1,CC(=N)NO.COC(=O)c1c(OC(=O)C(C)C)c2nccnc2n(C)c1=O>>Cc1noc(-c2c(O)c3nccnc3n(C)c2=O)n1,,Cc1ccccc1,,,,test
US04492708,CC#N.CC(C)n1c(N)nc2ccc(C(=O)c3ccccc3)cc21>>CC(C)n1c(N)nc2ccc(C(=CC#N)c3ccccc3)cc21,,CCOC(C)=O,O,C1CCOC1,[Li]CCCC,test
US20120015907A1,C=CCBr.COC(=O)C(C)(C)CO>>C=CCOCC(C)(C)C(=O)OC,,O,,CN(C)C=O,[H-].[Na+],test
US20140018373A1,COC(=O)Cl.Nc1cc(C(F)(F)F)cnc1N>>COC(=O)Nc1cc(C(F)(F)F)cnc1N,,c1ccncc1,,,,test
US05276187,CC(=NO)c1ccccc1.O=C(Oc1ccccc1)Oc1ccccc1>>CC(=NO)c1ccccc1.O=C(O)O,,Cc1ccccc1,,,,test
US20160106754A1,CC(=O)NN1C(=O)C2=C(CC13CCOCC3)Nc1ccc(OC(F)(F)F)cc1S2>>NN1C(=O)C2=C(CC13CCOCC3)Nc1ccc(OC(F)(F)F)cc1S2,,CO,,Cl,,test
US20150315198A1,CN(C)C=O.Clc1ccc2cc(Br)sc2n1>>O=Cc1cc2ccc(Cl)nc2s1,,C1CCOC1,,[Li]CCCC,,test
US20050032786A1,CCOC(=O)c1ccnc(C#N)c1.COC(=O)c1ccccc1S>>CCOC(=O)c1ccnc(-c2nc(=O)c3ccccc3s2)c1,,Cc1ccccc1,,CCN(CC)CC,,test
US20090082440A1,CC(C)(COS(=O)(=O)CCCCl)[C@@H](OCc1ccccc1)C(=O)O.OCCN1CCOCC1>>CC(C)(COS(=O)(=O)CCCCl)[C@@H](OCc1ccccc1)C(=O)OCCN1CCOCC1,,ClCCl,,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20020019569A1,CCOC(COCCCCOc1c(CC)cc(O)cc1CC)OCC.ClCC=C(Cl)Cl>>CCOC(COCCCCOc1c(CC)cc(OCC=C(Cl)Cl)cc1CC)OCC,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150232452A1,CCn1cc(-c2cccc(N)c2)c(-c2ccncc2)n1.Cc1ccc(N=C=O)cc1>>CCn1cc(-c2cccc(NC(=O)Nc3ccc(C)cc3)c2)c(-c2ccncc2)n1,,ClCCl,,,,test
US04408052,CCCCCCCC(C(=O)O)C1=C(C)C(=O)C(OC)=C(OC)C1=O.CCN(CC)CC.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COC1=C(OC)C(=O)C(CCCCCCCCCN=C=O)=C(C)C1=O,,Cc1ccccc1,,,,test
US20050203078A1,C[C@H](N)c1nc2cc(Cl)ccc2[nH]1.O=C(O)c1ccc(N2CC=CCO2)c(Cl)c1>>C[C@H](NC(=O)c1ccc(N2CC=CCO2)c(Cl)c1)c1nc2cc(Cl)ccc2[nH]1,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20120108583A1,CCOC(=N)C1CC1.COC(=O)c1cc2nc(Nc3c(Cl)cccc3Cl)[nH]c2c(N)c1O>>COC(=O)c1cc2nc(Nc3c(Cl)cccc3Cl)[nH]c2c2nc(C3CC3)oc12,,ClCCl,,Cl,,test
US20010047020A1,CCOC(=O)c1cccc2nc(OCC)n(Cc3ccc(-c4ccccc4-c4nnn[nH]4)cc3)c12>>CCOc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,CCO,,[Na+].[OH-],,test
US20060046999A1,CCSc1c(C(=O)c2ccccc2)ccc(=O)n1C.NC1CCC1>>Cn1c(NC2CCC2)c(C(=O)c2ccccc2)ccc1=O,,CCO,,,,test
US20100105650A1,CC(C)(C)OC(=O)N1CC[C@@H](O)C1.CC(O)=S>>CC(=O)S[C@H]1CCN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05128351,CCCCCCCCCCCCCCCCOc1ccc(OCC(=O)OC)cc1>>CCCCCCCCCCCCCCCCOc1ccc(OCC(=O)O)cc1,,CCO,O,Cl,[K+].[OH-],test
US20130005743A1,COc1ccc(-n2nc(C)c3c(O)ccnc32)cc1.O=P(Br)(Br)Br>>COc1ccc(-n2nc(C)c3c(Br)ccnc32)cc1,,CC#N,,,,test
US20040121964A1,CC[C@H]1CC[C@@H](C(=O)O)N1C(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C.N>>CC[C@H]1CC[C@@H](C(N)=O)N1C(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C,,C1CCOC1,C1COCCO1,CCN(CC)CC,CCOC(=O)Cl,test
US20110183980A1,NC1CCCCC1.O=C(O)c1ccc(Br)nc1>>O=C(NC1CCCCC1)c1ccc(Br)nc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150064175A1,O=C(C=P(c1ccccc1)(c1ccccc1)c1ccccc1)c1ccncc1.O=Cc1ccc2ccc(C(F)(F)F)cc2n1>>O=C(C=Cc1ccc2ccc(C(F)(F)F)cc2n1)c1ccncc1,,Cc1ccccc1,,,,test
US20070078135A1,CCC(=O)Cl.Clc1ccc(-c2ncc(C3CCNCC3)nc2-c2ccc(Cl)cc2)cc1>>CCC(=O)N1CCC(c2cnc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)n2)CC1,,ClCCl,,,,test
US20120101116A1,COc1cc2nc[nH]c(=O)c2cc1OC(C)=O.O=S(Cl)Cl>>COc1cc2ncnc(Cl)c2cc1OC(C)=O,,CN(C)C=O,,,,test
US20010056092A1,CCOc1c(Nc2cccc(C(F)(F)F)c2)c(=O)c1=O.Nc1ccc(Br)cc1-c1nnn[nH]1>>O=c1c(Nc2cccc(C(F)(F)F)c2)c(Nc2ccc(Br)cc2-c2nnn[nH]2)c1=O,,CC#N,,CCN(CC)CC,Cl,test
US20090036448A1,CC(=N)N.CCOC(=O)C(C)C(=O)OCC>>Cc1nc(O)c(C)c(O)n1,,CCO,O,Cl,Cl,test
US20120171245A1,CN(CCN[C@@H]1CCC[C@H](Nc2nc(-c3c[nH]c4ncc(Cl)cc34)ncc2F)C1)C(=O)OC(C)(C)C>>CNCCN[C@@H]1CCC[C@H](Nc2nc(-c3c[nH]c4ncc(Cl)cc34)ncc2F)C1,,CO,ClCCl,C1COCCO1,Cl,test
US20140114068A1,CC(C)c1ccc2c(c1)OC1(O)c3cccc([N+](=O)[O-])c3C(=O)C21NC(=O)c1cnc2ccccc2c1>>CC(C)c1ccc2c(c1)OC1(O)c3cccc(N)c3C(=O)C21NC(=O)c1cnc2ccccc2c1,[Fe],CCO,,Cl,O,test
US08431604B2,CC(C)(C)c1cc(NC(N)=S)n[nH]1.CI>>CSC(=N)Nc1cc(C(C)(C)C)[nH]n1.I,,CO,,,,test
US06107300,CCCn1nnc2c(Nc3ccc(C(C)C)cc3Br)nc(C)nc21.CCI>>CCCn1nnc2c(N(CC)c3ccc(C(C)C)cc3Br)nc(C)nc21,,CN(C)C=O,,[H-].[Na+],,test
US20020018843A1,CN.O=Cc1c2ccccc2c(CO)c2ccccc12>>CN=Cc1c2ccccc2c(CO)c2ccccc12,,CO,,,,test
US04123537,CC(C)(C)c1cc(CN)c(O)cn1.ClI>>CC(C)(C)c1cc(CN)c(O)c(I)n1,,Cl,O,[NH4+].[OH-],,test
US20160185775A1,CCCC(C)(CNC(=O)c1c(C)nn2c(OCCC(C)C)cc(C)cc12)NC(=O)OC(C)(C)C>>CCCC(C)(N)CNC(=O)c1c(C)nn2c(OCCC(C)C)cc(C)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US06576656B1,CI.O=C1Nc2cc(Cl)cc(Cl)c2C1=O>>CN1C(=O)C(=O)c2c(Cl)cc(Cl)cc21,,C1CCOC1,,Cl,[H-].[Na+],test
US20090186879A1,CC(=O)OC(C)=O.CCC(O)c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(OC)nc1C>>CCC(OC(C)=O)c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(OC)nc1C,,c1ccncc1,,,,test
US05866573,Cc1nc(NC(=O)OC(C)(C)C)ccc1C#N>>Cc1nc(NC(=O)OC(C)(C)C)ccc1CN,[Pd],CC(=O)O,,,,test
US04230635,CCNS(=O)(=O)Cl.Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1>>CCNS(=O)(=O)Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20080261941A1,CC(C)(C)OC(=O)N1CCC(=Cc2cccc(Oc3ccc(F)cc3)c2)CC1.Cl>>Cl.Fc1ccc(Oc2cccc(C=C3CCNCC3)c2)cc1,,ClCCl,,CCOCC,,test
US20060128790A1,COc1c(C)cc(NC2(CC(=O)O)CCC2)cc1C>>COc1c(C)cc2c(c1C)C(=O)CC1(CCC1)N2,,Cc1ccccc1,,O,,test
US20040106642A1,COCCO[C@@H]1c2ccn3cc(C)nc3c2N(C(C)=O)[C@H](c2ccccc2)[C@H]1OC(=O)C(C)(C)C.O=C1CCC(=O)N1Br>>COCCO[C@@H]1c2ccn3c(Br)c(C)nc3c2N(C(C)=O)[C@H](c2ccccc2)[C@H]1OC(=O)C(C)(C)C,,CCO,,,,test
US20120178740A1,Cc1ccccc1C(=O)O.N.O=S(=O)(O)Cl>>Cc1cc(S(N)(=O)=O)ccc1C(=O)O,,ClC(Cl)Cl,O,Cl,,test
US09248117B2,COCC[N+](C)(C)CCC(C)(C)NC(=O)OCc1ccccc1.[Cl-]>>COCC[N+](C)(C)CCC(C)(C)N.[Cl-],[Pd],CO,,,,test
US06350749B1,Cc1ccc(C2CC(=O)c3c(C)ccnc3C2)s1.Cl.N=C(NN)NO>>Cc1ccc(C2CC(=NNC(=N)NO)c3c(C)ccnc3C2)s1.Cl,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05639884,CC(=O)OC(C)=O.O=S1(=O)Nc2ccccc2C1=Cc1ccc(O)cc1>>CC(=O)Oc1ccc(C=C2c3ccccc3NS2(=O)=O)cc1,,c1ccncc1,,,,test
US06211234B1,CC(=O)c1ccc(OCc2ccsc2)cc1OC(CCc1ccccc1C#N)C(=O)[O-]>>CC(=O)c1ccc(OCc2ccsc2)cc1OC(CCc1ccccc1C#N)C(=O)O,,CO,,Cl,[Na+].[OH-],test
US04243409,CCCCc1noc(-c2cccc(N)c2)n1.CN(C)C(=O)Cl>>CCCCc1noc(-c2cccc(NC(=O)N(C)C)c2)n1,,c1ccncc1,,,,test
US20100130506A1,CC(C(=O)OC(C)(C)C)c1ccc(O)cc1.COC(=O)CBr>>COC(=O)COc1ccc(CCC(=O)OC(C)(C)C)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US05159103,CC(C)(C)OC(=O)N[C@@H]1CCc2ccc(O)cc2C1.CCOC(=O)CBr>>CCOC(=O)COc1ccc2c(c1)C[C@H](NC(=O)OC(C)(C)C)CC2,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140135374A1,CCOC(=O)C1C(=O)CCCC1(C)C.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)C1=C(OS(=O)(=O)C(F)(F)F)CCCC1(C)C,,CCOCC,,[H-].[Na+],[Cl-].[NH4+],test
US05013736,N#Cc1c2cccccc-2nc1Cl.NCC(c1ccccc1)c1ccccc1>>N#Cc1c2cccccc-2nc1NCC(c1ccccc1)c1ccccc1,,CN(C)C=O,,O,,test
US20040092737A1,Cl.N=C(N)Cc1ccc2c(c1)Nc1nccnc1S2>>Cl.N=C(N)Cc1ccc2c(c1)Nc1nccnc1S2,,CCOC(C)=O,CO,,,test
US20100029650A1,CSc1ccc(-c2cnc(O[C@@H](C)C3CCN(C(=O)OC(C)C)CC3)cn2)c(F)c1.O=S([O-])OO>>CC(C)OC(=O)N1CCC([C@H](C)Oc2cnc(-c3ccc(S(C)(=O)=O)cc3F)cn2)CC1,,CC(C)=O,,O,,test
US20100029772A1,Br.OCc1cc(F)ccc1O.c1ccc([PH+](c2ccccc2)c2ccccc2)cc1>>Oc1ccc(F)cc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-],,CC#N,,,,test
US20110028486A1,NCc1ccc2[nH]c(C(F)(F)F)cc2c1.O=C(O)c1ccc(-c2cc[nH]n2)cc1>>O=C(NCc1ccc2[nH]c(C(F)(F)F)cc2c1)c1ccc(-c2cc[nH]n2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05849735,O=C(Cl)c1ccc(-c2ccccc2)cc1.c1ccc2c(c1)CNc1ccccc1O2>>O=C(c1ccc(-c2ccccc2)cc1)N1Cc2ccccc2Oc2ccccc21,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,,test
US04940710,CCn1cc(C(=O)O)c(=O)c2cc(F)c(F)cc21.FCC1CNCCN1>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(CF)C3)cc21,,c1ccncc1,,,,test
US05624942,CSc1cc(Cl)nc(OCc2ccsc2)c1.Oc1cccc(C(F)(F)F)c1>>CSc1cc(OCc2ccsc2)nc(Oc2cccc(C(F)(F)F)c2)c1,[Cu]I,CN(C)C=O,,[H-].[Na+],,test
US05977105,C=CC(=O)CCc1cccnc1.Sc1ccc2ccccc2c1>>O=C(CCSc1ccc2ccccc2c1)CCc1cccnc1,,CCO,,,,test
US05326760,CC(C)C[C@H](N[C@H](CCO)C(=O)OC(C)(C)C)C(=O)OCc1ccccc1.O=C1NC(=O)c2cc3ccccc3cc21>>CC(C)C[C@H](N[C@H](CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)OC(C)(C)C)C(=O)OCc1ccccc1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20010018436A1,C1CCNC1.CNc1ccccc1.Cc1nc(Cl)nc(Cl)c1[N+](=O)[O-]>>Cc1nc(N(C)c2ccccc2)nc(N2CCCC2)c1[N+](=O)[O-],,CCO,ClCCl,,,test
US20030130270A1,BrCc1ccc(Br)cc1.OC1CCOCC1>>Brc1ccc(COC2CCOCC2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20070254881A1,CC(=O)c1c[nH]c(C)n1.Cc1ccc(S(=O)(=O)Cl)cc1>>CC(=O)c1cn(S(=O)(=O)c2ccc(C)cc2)c(C)n1,,ClCCl,O,CCN(CC)CC,CCOC(C)=O,test
US20150141400A1,CC(C)(C)OC(=O)N[C@H]1CCNC1.CCOC(=O)c1cc(C(F)(F)F)c(C=O)cc1N>>CCOC(=O)c1cc(C(F)(F)F)c(CN2CC[C@H](NC(=O)OC(C)(C)C)C2)cc1N,,C1CCOC1,CCOC(C)=O,O=C([O-])O.[Na+],,test
US20080269059A1,NC1CCC1.O=C(O)c1ccc(C(F)(F)F)[nH]c1=O>>O=C(NC1CCC1)c1ccc(C(F)(F)F)[nH]c1=O,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20150282482A1,N#CN.O=C(Cl)c1cc2cc(C(F)(F)F)ccc2s1>>N#CNC(=O)c1cc2cc(C(F)(F)F)ccc2s1,,CCOC(C)=O,,CCN(CC)CC,ClCCl,test
US20090233915A1,COC(=O)CCCCN.O=Cc1cc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)c(F)c1F>>O=C(NOCCO)c1cc(CN2CCCCC2=O)c(F)c(F)c1Nc1ccc(I)cc1F,,C1CCOC1,,Cl,[BH3-]C#N.[Na+],test
US04346088,CN1C(=Nc2ccccc2Cl)SCC1(O)c1ccc(Cl)c(S(=O)(=O)N(C)C)c1>>CN(C)S(=O)(=O)c1cc(-c2csc(=Nc3ccccc3Cl)n2C)ccc1Cl,,CCN(CC)CC,CO,Br,O,test
US20070275950A1,COC(=O)c1ccnc(-c2ccc(O)c(C#N)c2)c1.CSCCCO>>COC(=O)c1ccnc(-c2ccc(OCCCSC)c(C#N)c2)c1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20130303510A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(Nc1ccc(CC2CCNCC2)cc1)C(F)(F)F>>CC(C)(C)OC(=O)N1CCC(Cc2ccc(N)cc2)CC1,,ClCCl,,CCN(CC)CC,[Na+].[OH-],test
US20130281433A1,CC1(C)OB(c2cc(Cl)ncc2F)OC1(C)C.CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(Br)sc2c1-c1ccc(Cl)cc1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3cc(Cl)ncc3F)sc2c1-c1ccc(Cl)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100286211A1,N#Cc1ccc(Br)cc1F.NNC(N)=S>>Nc1nnc(-c2ccc(Br)cc2F)s1,,O=C(O)C(F)(F)F,,,,test
US20150376169A1,CC(C)(C)[Si](C)(C)Cl.CNc1ccc(O)cc1>>CNc1ccc(O[Si](C)(C)C(C)(C)C)cc1,,ClCCl,,O,c1c[nH]cn1,test
US20070197603A1,Cc1c(C=O)[nH]c2ccccc12.Clc1cccc(Cl)c1C1CCNCC1>>Cc1c(CN2CCC(c3c(Cl)cccc3Cl)CC2)[nH]c2ccccc12,CC(=O)O,CO,,[BH3-]C#N.[Na+],,test
US20110136871A1,CC1(C)OC[C@@H](CCl)O1.COc1ccc(C=O)cc1>>CC1(C)OC[C@@H](COc2ccc(C=O)cc2)O1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120202785A1,C1COCCN1.CN(C)C(On1nnc2cccnc21)=[N+](C)C.C[C@H](Nc1ncnc2c1ncn2C1CCCCO1)c1nc2ccc(F)c(C(=O)O)c2n1-c1ccccc1>>CC(Nc1ncnc2[nH]cnc12)c1nc2ccc(F)c(C(=O)N3CCOCC3)c2n1-c1ccccc1.[NH4+].[OH-],,ClCCl,O,CCN(C(C)C)C(C)C,,test
US20110039852A1,CCN(Cc1cc(C(F)(F)F)ccc1B1OC(C)(C)C(C)(C)O1)C(=O)NC.COC(=O)Cc1cc(OS(=O)(=O)C(F)(F)F)cc(C(F)(F)F)c1>>CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)OC)cc(C(F)(F)F)c1)C(=O)NC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20080242675A1,CN1CCN(c2cc(CC(=O)OC(C)(C)C)c(C(F)(F)F)cn2)CC1.N>>CN1CCN(c2cc(CC(N)=O)c(C(F)(F)F)cn2)CC1,,ClCCl,O=C(O)C(F)(F)F,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US20160176861A1,COC(=O)c1ncoc1C1CC1>>COC(=O)C(N)C(=O)C1CC1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20040176446A1,CC#N.COC(=O)CCCCBr.COC(=O)c1ccc(CNCCc2cc(OC(F)(F)F)ccc2OCc2ccc(Br)cc2)cc1>>CCOC(=O)CCCCN(CCc1cc(OC(F)(F)F)ccc1OCc1ccc(Br)cc1)Cc1ccc(C(=O)OC)cc1,,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20100056586A1,CCOC(=O)N=C=S.COC(=O)C(N)Cc1ccc(Cl)cc1>>CCOC(=O)NC(=S)NC(Cc1ccc(Cl)cc1)C(=O)OC,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090047246A1,CCOC(=O)Cc1cn(Cc2csc3c(N(C)C=O)cc(Cl)cc23)c2cc(-c3cc([N+](=O)[O-])cc([N+](=O)[O-])c3)ccc12>>CCOC(=O)Cc1cn(Cc2csc3c(NC)cc(Cl)cc23)c2cc(-c3cc([N+](=O)[O-])cc([N+](=O)[O-])c3)ccc12,,CCO,ClCCl,Cl,,test
US05574064,CC(N)CO.Clc1ncccn1>>CC(N)COc1ncccn1,,CN(C)C=O,,[H-].[Na+],,test
US20050159599A1,CS(=O)(=O)N(CCl)CCl.O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(SC(F)(F)F)cc1F>>CS(=O)(=O)N1CN(C(=O)c2c(F)cccc2F)C(=O)N(c2ccc(SC(F)(F)F)cc2F)C1,,CN(C)C=O,O,[H-].[Na+],[Cl-].[NH4+],test
US20150203515A1,COC(=O)C12CCC(NCc3ccc4cc(O)ccc4c3)(CC1)CC2.C[Si](C)(C)[C@H]1CC[C@@H](OS(C)(=O)=O)CC1>>COC(=O)C12CCC(NCc3ccc4cc(O[C@@H]5CC[C@@H]([Si](C)(C)C)CC5)ccc4c3)(CC1)CC2,,CN(C)C=O,O,Cl,[Na+].[OH-],test
US05412137,BrCCCCCOCc1ccccc1.CCCCC=Cc1cccc(Br)c1>>CCCCC=Cc1cccc(CCCCCOCc2ccccc2)c1,,C1CCOC1,CCCCCC,[Li]C(C)(C)C,,test
US20070244333A1,COC(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](OC2CCCCO2)[C@@H]1CO[Si](C)(C)C(C)(C)C>>COC(=O)CCCCCC[C@H]1[C@@H](O)C[C@@H](OC2CCCCO2)[C@@H]1CO[Si](C)(C)C(C)(C)C,[Pd],CCOC(C)=O,,,,test
US20020038025A1,CN(C)CCCC#Cc1ccc(N(C)C(=O)OC(C)(C)C)cc1>>CNc1ccc(C#CCCCN(C)C)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090221577A1,CCOC(=O)C1CCN(C(=O)c2ccc(CC)cc2)CC1>>CCc1ccc(C(=O)N2CCC(C(=O)O)CC2)cc1,,CO,,[Na+].[OH-],,test
US20090143368A1,CC1=CC(=O)OC(C)(C)O1.COC(=O)c1cccnc1N>>COC(=O)c1cccnc1NC(=O)CC(C)=O,,Cc1ccccc1C,,,,test
US04840971,CCOc1ccc(C(CO)C(F)(F)F)cc1.Fc1ccc(Oc2cccc(CBr)c2)cc1>>CCOc1ccc(C(COCc2cccc(Oc3ccc(F)cc3)c2)C(F)(F)F)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20090264498A1,CC(C)(C)OC(=O)N1CC[C@@H](N)C1.O=S(=O)(Cl)c1cccc(Br)c1>>CC(C)(C)OC(=O)N1CC[C@@H](NS(=O)(=O)c2cccc(Br)c2)C1,,CN(C)C=O,,CCN(CC)CC,,test
US20060160794A1,CC(=O)Cl.CN(Cc1ccccc1Cl)C(=O)c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1N1CCNCC1>>CC(=O)N1CCN(c2c(C(=O)N(C)Cc3ccccc3Cl)nnn2Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1,,ClCCl,O,CCN(CC)CC,,test
US04772600,CCOC(=O)N1CCNCC1.O=C(O)Cn1c(-c2ccc(Cl)cc2)nc2cccnc21>>CCOC(=O)N1CCN(C(=O)Cn2c(-c3ccc(Cl)cc3)nc3cccnc32)CC1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20070149508A1,CC(C)(C)OC(=O)N1CCC(N)CC1.CI>>CNC1CCN(C(=O)OC(C)(C)C)CC1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20030083238A1,CO.OCCCCCCCBr>>COCCCCCCCO,,CO,,C[O-].[Na+],,test
US20090023720A1,CCN=C=S.Cc1nc(Oc2ccccc2)c(N)c(NCC(C)C)c1C>>CCNc1nc2c(Oc3ccccc3)nc(C)c(C)c2n1CC(C)C,,CCOC(C)=O,c1ccncc1,CCN(CC)CC,,test
US20110224204A1,N#Cc1ccc(O)c(-c2ccc(OCc3ccc4ccccc4n3)cc2)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>N#Cc1ccc(OS(=O)(=O)C(F)(F)F)c(-c2ccc(OCc3ccc4ccccc4n3)cc2)c1,,c1ccncc1,,,,test
US20100272678A1,COC(=O)c1ccc(C)[se]1.O=[Se]=O>>COC(=O)c1ccc(C=O)[se]1,,CC(=O)O,,O,,test
US20060079696A1,C[C@H]1CNC[C@@H](C)C1.N#Cc1ccccc1F>>C[C@@H]1C[C@H](C)CN(c2ccccc2C#N)C1,,CC#N,Cc1ccccc1,O=C(O)CC(O)(CC(=O)O)C(=O)O,,test
US20150087639A1,COC(=O)/C=C(/C)N.O=C(Cl)CCc1cccc(F)c1>>COC(=O)/C=C(/C)NC(=O)CCc1cccc(F)c1,,ClCCl,,c1ccncc1,,test
US20100249142A1,CN.Clc1nc2ccccc2n2ccnc12>>CNc1nc2ccccc2n2ccnc12,,CCO,ClCCl,CO,O,test
US04426381,CN1CCNCC1.O=C(O)c1c2n(c3cc(Cl)c(F)cc3c1=O)CCS2>>CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)c2n3CCS2)CC1,,c1ccncc1,,,,test
US20130210796A1,C1O[C@@H]2CN[C@H]1C2.NC(=O)c1cc(-n2nnnc2CCl)cc(C(F)(F)F)c1>>NC(=O)c1cc(-n2nnnc2CN2C[C@@H]3C[C@H]2CO3)cc(C(F)(F)F)c1,,CC#N,,Cl,,test
US20150291572A1,CCC1(S(=O)(=O)c2cccc(C(F)(F)F)c2)CCOC(C(=O)NC(=NO)C2CC2)C1>>CCC1(S(=O)(=O)c2cccc(C(F)(F)F)c2)CCOC(c2nc(C3CC3)no2)C1,,CCO,O,CC(=O)[O-].[Na+],,test
US20100130468A1,Brc1csc(Br)n1.CC1(C)OB(c2cc(C(N)=O)c3[nH]cc(C4CCS(=O)(=O)CC4)c3c2)OC1(C)C>>NC(=O)c1cc(-c2nc(Br)cs2)cc2c(C3CCS(=O)(=O)CC3)c[nH]c12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20130116243A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)NC(=S)CO4)cc2)CCC1.NNC(=O)CC(F)(F)F>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)-n3c(nnc3CC(F)(F)F)CO4)cc2)CCC1,,Cc1ccc(C)cc1,,,,test
US04465834,CCOC(=O)C(O)(C#Cc1ccccc1)c1ccccc1.OC1CN2CCC1CC2>>O=C(OC1CN2CCC1CC2)C(O)(C#Cc1ccccc1)c1ccccc1,,Cc1ccccc1,,[Na],,test
US20100184761A1,COC(=O)c1cccc(CO)n1.CS(=O)(=O)Cl>>COC(=O)c1cccc(COS(C)(=O)=O)n1,,ClCCl,,,,test
US20090118296A1,COC(=O)c1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1.NN>>NNC(=O)c1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1,,CO,,O,,test
US20140315879A1,Cc1cc(F)c(C(=O)NS(=O)(=O)N(C)C)cc1F.O=C1CCC(=O)N1Br>>CN(C)S(=O)(=O)NC(=O)c1cc(F)c(CBr)cc1F,CC(C)(C#N)N=NC(C)(C)C#N,ClCCCl,,,,test
US05109017,CC(=O)OC(C)=O.Cc1ccsc1C(N)Cc1ccccc1>>CC(=O)ONC(Cc1ccccc1)c1sccc1C,,c1ccncc1,,,,test
US20100029650A1,CC(C)c1noc(N2CCC(COS(C)(=O)=O)CC2)n1.CSc1ccc(-c2ccc(O)cn2)c(F)c1>>CSc1ccc(-c2ccc(OCC3CCN(c4nc(C(C)C)no4)CC3)cn2)c(F)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20070287716A1,COc1ccccc1Oc1cccc([N+](=O)[O-])c1>>COc1ccccc1Oc1cccc(N)c1,[Fe],CCO,,Cl,,test
US20030195176A1,CC(C)(O)CCSCC1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>CC(C)(O)CCSCC1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04595535,CI.Cc1nc(Cc2ccccc2N=C=S)n[nH]1>>CSC1=Nc2ccccc2Cc2nc(C)nn21,,C1CCOC1,,O,[H-].[Na+],test
US06011174,CCOC(=O)C1(C(=O)OCC)O[C@@H](C(=O)[O-])[C@H](C(=O)OC(C)(C)C)O1.C[C@@H](NCC(=O)OC(C)(C)C)[C@H](CCc1ccccc1)c1ccc(Oc2ccccc2)cc1>>CCOC(=O)C1(C(=O)OCC)O[C@@H](C(=O)OC(C)(C)C)[C@H](C(=O)N(CC(=O)OC(C)(C)C)[C@H](C)[C@H](CCc2ccccc2)c2ccc(Oc3ccccc3)cc2)O1,,ClC(Cl)Cl,O,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US04011339,CCOC(=O)C#CCC(C)(C)c1ccc(Cl)cc1>>CC(C)(C=C=CC(=O)O)c1ccc(Cl)cc1,,CCO,,[Na+].[OH-],,test
US20050256078A1,CCOP(=O)(CCNCC(C)=CCc1c(CC)c(C)c2c(c1OCC[Si](C)(C)C)C(=O)OC2)OCC>>CCc1c(C)c2c(c(O)c1CC=C(C)CNCCP(=O)(O)O)C(=O)OC2,,CN(C)C=O,ClCCl,C[Si](C)(C)Br,,test
US20160096834A1,CC(C)(C)C(=O)NN.COC(=O)C(=O)Cl>>COC(=O)C(=O)NNC(=O)C(C)(C)C,,ClCCl,O,,,test
US20080269213A1,O=C(COc1ccccc1)NC(c1ccccc1)c1cc([N+](=O)[O-])c2cccnc2c1O>>Nc1cc(C(NC(=O)COc2ccccc2)c2ccccc2)c(O)c2ncccc12,[Pd],C1CCOC1,,,,test
US05157160,CC(=O)O.COC(=O)C12CCCN(C1)C2.COCC(N)=NO>>COCc1noc(C23CCCN(C2)C3)n1.O=C(O)C(=O)O,,CC(=O)O,CO,[Na],C[O-].[Na+],test
US20090137609A1,CCC(CC)(c1ccc(CCC2(O)CCCCC2)c(C)c1)c1ccc(-c2ccc(CC(=O)OC)c(F)c2)c(C)c1>>CCC(CC)(c1ccc(CCC2(O)CCCCC2)c(C)c1)c1ccc(-c2ccc(CC(=O)O)c(F)c2)c(C)c1,,CO,,[Na+].[OH-],[Cl-].[NH4+],test
US20150344481A1,BrCCBr.OCc1nc(-c2ccc(F)cc2)c[nH]1>>Fc1ccc(-c2cn3c(n2)COCC3)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05366987,BrP(Br)Br.CCCCCCCCCCCCc1cc(CO)on1>>CCCCCCCCCCCCc1cc(CBr)on1,,ClCCl,,,,test
US05610161,CCOC(=O)C1CCNC2(CCCCC2)C1=O>>O=C1CCCNC12CCCCC2,,O,,Cl,,test
US20030139544A1,C1=CCC(C2C3CC4CC(C3)CC2C4)=C1.O=C(c1ccccc1)c1ccccc1>>C1=CC(=C(c2ccccc2)c2ccccc2)C=C1C1C2CC3CC(C2)CC1C3,,CCO,,C[O-].[Na+],,test
US04966898,C[C@]12CC[C@H](OC3CCCCO3)C(F)(F)C1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(=NC3CC3)CC[C@@H]12>>C[C@]12CC[C@H](OC3CCCCO3)C(F)(F)C1=CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](NC3CC3)CC[C@@H]12,,CCO,,[BH4-].[Na+],,test
US20150005282A1,COC(=O)C[C@@H]1COc2cc(OCc3cccc(-c4c(C)cc(OC5CCN(S(C)(=O)=O)CC5)cc4C)c3)ccc21>>Cc1cc(OC2CCN(S(C)(=O)=O)CC2)cc(C)c1-c1cccc(COc2ccc3c(c2)OC[C@H]3CC(=O)O)c1,,CCO,,Cl,[Na+].[OH-],test
US20090054411A1,CCOc1ccc([N+](=O)[O-])cc1Br>>CCOc1ccc(N)cc1Br,[Fe],CCO,,Cl,,test
US04810702,C=CCOC(=O)/C(=N\O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1.C[C@@H](Cl)C(=O)OC(c1ccccc1)c1ccccc1>>C[C@H](ON=C(C(=O)O)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1)C(=O)OC(c1ccccc1)c1ccccc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040082609A1,C[C@@H](CC#N)Nc1ccccc1.O=S(=O)(O)O>>C[C@@H](CC(N)=O)Nc1ccccc1,,Cc1ccccc1,O,,,test
US20060235013A1,CCOC(=O)c1n[nH]c2c1CNC2.CCc1cccc(CC)c1N=C=O>>CCOC(=O)c1n[nH]c2c1CN(C(=O)Nc1c(CC)cccc1CC)C2,,CN(C)C=O,,CCN(CC)CC,O,test
US20100222319A1,CCNc1nc(-c2ccc(N)cc2)ccc1C(=O)NC.NCc1ccc(N)nc1.O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O>>CCNc1nc(-c2ccc(NC(=O)NCc3ccc(N)nc3)cc2)ccc1C(=O)NC,,C1CCOC1,CCN(CC)CC,CN(C)c1ccccn1,,test
US20160052888A1,CC(C)O[Si](C)(C)C.O=CCC[C@@H]1CCc2cc([C@H]3CC[C@]4(COC(=O)N4)C3)ccc2C1>>CC(C)OCCC[C@@H]1CCc2cc([C@H]3CC[C@]4(COC(=O)N4)C3)ccc2C1,,C[N+](=O)[O-],,CC[SiH](CC)CC,,test
US20030199440A1,CC(C)(C)OC(=O)CCNS(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1.N=C(N)N>>CC(C)(C)OC(=O)CCNS(=O)(=O)c1ccc2c(Cl)cnc(NC(=N)N)c2c1,,CCOC(C)=O,COCCOC,Cl,[H-].[Na+],test
US20120035363A1,COc1cc2nc[nH]c(=O)c2cc1OC(C)=O.Nc1cccc(Cl)c1F.O=P(Cl)(Cl)Cl>>COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC(C)=O.Cl,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20150223460A1,CSc1cccc(-n2nnn(C)c2=O)c1CBr.Cc1cc(-c2nn(C)c(Cl)c2C)ccc1O>>CSc1cccc(-n2nnn(C)c2=O)c1COc1ccc(-c2nn(C)c(Cl)c2C)cc1C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05374772,CCCCCCCCCCCCCCCCCCOc1cc(OCCCOc2ccc(OCc3ccccc3)cc2)cc(C(=O)OC)c1>>CCCCCCCCCCCCCCCCCCOc1cc(OCCCOc2ccc(O)cc2)cc(C(=O)OC)c1,[Pd],C1CCOC1,,[H][H],,test
US04739065,CCOC(=O)c1cn(CC)c2sc(C=O)cc2c1=O.NO>>CCOC(=O)c1cn(CC)c2c(c1=O)CC(=NO)S2,,CCO,,Cl,[Na+].[OH-],test
US20090156610A1,CC1(C)CC(OS(C)(=O)=O)CC(C)(C)O1.O=Cc1cc(Cl)ccc1O>>CC1(C)CC(Oc2ccc(Cl)cc2C=O)CC(C)(C)O1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100278833A1,C[C@@H](Oc1cc(-n2cnc3cnc(COS(C)(=O)=O)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F.O=C(CN1CCNCC1)N1CCCC1>>C[C@@H](Oc1cc(-n2cnc3cnc(CN4CCN(CC(=O)N5CCCC5)CC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F,,ClCCl,,,,test
US20130085157A1,COc1ccc(COS(C)(=O)=O)cc1OC.Fc1ccc(-c2c(-c3c(F)cccc3Cl)sc3nnc(S)n23)cc1>>COc1ccc(CSc2nnc3sc(-c4c(F)cccc4Cl)c(-c4ccc(F)cc4)n23)cc1OC,,ClCCl,,CCN(CC)CC,,test
US20110118266A1,Cn1nc(N2CCNCC2)c(=O)n(C)c1=O.Fc1ccc(CBr)c(C(F)(F)F)c1>>Cn1nc(N2CCN(Cc3ccc(F)cc3C(F)(F)F)CC2)c(=O)n(C)c1=O,,Cc1ccccc1,,CCN(CC)CC,O,test
US20120252759A1,CC(C)(C)OC(=O)Nc1cscn1.O=C1CCC(=O)N1I>>CC(C)(C)OC(=O)Nc1ncsc1I,,CC(Cl)Cl,,,,test
US03940394,CCOC(=O)CSc1nc(Cl)cc(NCc2ccc(Cl)cc2)n1.NN>>NNC(=O)CSc1nc(Cl)cc(NCc2ccc(Cl)cc2)n1,,CCO,,O,O=C([O-])[O-].[Na+].[Na+],test
US20140206663A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Clc1ccc(N2CCNCC2)cc1Cl>>CC(C)(C)OC(=O)N1CCN(c2ccc(Cl)c(Cl)c2)CC1,,ClCCl,,,,test
US20040082607A1,CCCCOc1c(CNC(=O)OC(C)(C)C)n(CC(C)C)c(=O)c2ccc(O)cc12.NC(=O)CI>>CCCCOc1c(CNC(=O)OC(C)(C)C)n(CC(C)C)c(=O)c2ccc(OCC(N)=O)cc12,,CN(C)C=O,,C1CCC2=NCCCN2CC1,O,test
US20130123259A1,CC1(C)O/C(=C2/C(=O)Nc3ccc(F)cc32)C=C1Br.O=Cc1ccc(B(O)O)cc1>>CC1(C)O/C(=C2/C(=O)Nc3ccc(F)cc32)C=C1c1ccc(C=O)cc1,,C1CCOC1,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20110049427A1,CC=Cc1ccc(-c2ccc(-c3ccc(CC)cc3)cc2F)s1>>CCCc1ccc(-c2ccc(-c3ccc(CC)cc3)cc2F)s1,[Pd],C1CCOC1,,,,test
US20070299056A1,O=C(O)CCCOc1ccc2c(c1)CCN(C1CCC1)CC2.O=C(n1ccnc1)n1ccnc1>>O=C(CCCOc1ccc2c(c1)CCN(C1CCC1)CC2)n1ccnc1,,CN(C)C=O,,,,test
US20080261920A1,CC(C)(C)OC(=O)N1[C@H](CO)COC1(C)C.Sc1nc2ccccc2s1>>CC(C)(C)OC(=O)N1[C@H](CSc2nc3ccccc3s2)COC1(C)C,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110319394A1,Cn1c(Oc2ccc(Nc3ncnc(Cl)c3[N+](=O)[O-])cc2)nc2ccccc21>>Cn1c(Oc2ccc(Nc3ncncc3N)cc2)nc2ccccc21,[Pd],C1CCOC1,CO,,,test
US05597918,CC(=O)O.Cc1ccc(N2N=C3c4cc(C(=O)CCl)sc4CCC3CC2=O)cc1>>CC(=O)OCC(=O)c1cc2c(s1)CCC1CC(=O)N(c3ccc(C)cc3)N=C21,,CC(=O)O,,CC(=O)[O-].[K+],,test
US04171369,NC(=O)C1CC1.c1ccc(C2c3ccccc3CC3CNCC32)cc1>>c1ccc(C2c3ccccc3CC3CN(CC4CC4)CC32)cc1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050014811A1,Nc1ccc(OS(=O)(=O)c2ccc(F)cc2)cc1[N+](=O)[O-].c1c[nH]cn1>>Nc1ccc(OS(=O)(=O)c2ccc(-n3ccnc3)cc2)cc1[N+](=O)[O-],,CN(C)C=O,,,,test
US20030216571A1,Cl.O=C(CCSC1c2ccccc2COc2ccc(/C=C/c3ccc4cc(F)c(F)cc4n3)cc21)NS(=O)(=O)C(F)(F)F>>Cl.O=C(CCSC1c2ccccc2COc2ccc(/C=C/c3ccc4cc(F)c(F)cc4n3)cc21)NS(=O)(=O)C(F)(F)F,,C1CCOC1,O,[Na],,test
US20090270350A1,CSc1ccccc1Cn1c(C)cc(OCc2ccccc2CNC(=O)Nc2cc(C(C)(C)C)nn2-c2cccc(OCCOC3CCCCO3)c2)c(Cl)c1=O>>CSc1ccccc1Cn1c(C)cc(OCc2ccccc2CNC(=O)Nc2cc(C(C)(C)C)nn2-c2cccc(OCCO)c2)c(Cl)c1=O,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20120277325A1,CC(=O)CCC1=C(C)CCC(C)C1(C)C.CCCCO.N=CN>>CC1=C(CCc2ccncn2)C(C)(C)C(C)CC1,,CCCCO,,CC(=O)O,,test
US05792763,CN1CCC(c2coc3ccc(N)cc23)CC1.CS(=O)(=O)Cl>>CN1CCC(c2coc3ccc(NS(C)(=O)=O)cc23)CC1.Cl,,ClCCl,,C1CCNCC1,,test
US20140364432A1,C[C@@H]1CCCN[C@@H]1CN1C(=O)c2ccccc2C1=O.O=C(O)c1cc(F)c(F)cc1I>>C[C@@H]1CCCN(C(=O)c2cc(F)c(F)cc2I)[C@@H]1CN1C(=O)c2ccccc2C1=O,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080242704A1,Cc1ccc([N+](=O)[O-])cc1N=C=O.N#Cc1ccc(C(=O)CN=[N+]=[N-])cc1>>Cc1ccc([N+](=O)[O-])cc1Nc1ncc(-c2ccc(C#N)cc2)o1,,C1COCCO1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20020193314A1,O=C(OC[C@H]1O[C@H](Cl)C[C@@]1(O)C(=O)c1ccc(Cl)cc1)c1ccc(Cl)cc1.O=P(O)(O)O>>O=C(OC[C@H]1O[C@H](OP(=O)(O)O)C[C@@]1(O)C(=O)c1ccc(Cl)cc1)c1ccc(Cl)cc1,,CC#N,,CCCCN(CCCC)CCCC,,test
US20140323470A1,CN1CCN(CCc2nnc3ccc(O[C@@H]4CC[C@H](N)c5ccccc54)cn23)CC1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1.O=CO>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(CCN5CCN(C)CC5)n4c3)c3ccccc32)cc1.O=CO,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20030176460A1,CC(C)(C)OC(=O)N[C@H](Cc1ccc([N+](=O)[O-])cc1)CN1CCC(C(=O)c2ccc(F)cc2)CC1>>CC(C)(C)OC(=O)N[C@H](Cc1ccc(N)cc1)CN1CCC(C(=O)c2ccc(F)cc2)CC1,[Zn],CC(=O)O,,[Ca+2].[Cl-].[Cl-],,test
US06515167B1,CC(C(=O)O)c1ccccc1.ClCCl>>COC(=O)C(C)c1ccccc1,,ClCCl,O,C1CCC2=NCCCN2CC1,,test
US05338853,CC1(C)CC(NC(=O)C(=O)NN)CC(C)(C)N1.CCC(=O)OC(=O)CC>>CCC(=O)NNC(=O)C(=O)NC1CC(C)(C)NC(C)(C)C1,,C1CCOC1,,,,test
US20100029650A1,CC(C)c1noc(N2CCC(CO)CC2)n1.CS(=O)(=O)c1ccc(-c2ccc(O)cn2)cc1>>CC(C)c1noc(N2CCC(COc3ccc(-c4ccc(S(C)(=O)=O)cc4)nc3)CC2)n1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06166006,CC=O.NCc1ccc([N+](=O)[O-])cc1.O=C1CCOCC1>>O=[N+]([O-])c1ccc(CNCCC2CCOCC2)cc1,,ClCCCl,,CCN(CC)CC,Cl,test
US20130059835A1,C1CCNC1.CCOc1c(C(C)=O)cc(Cl)c(C#N)c1I>>CCOc1c(C(C)=O)cc(Cl)c(C#N)c1N1CCCC1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020169200A1,C#Cc1cc(Cl)cc(Cl)c1.CCOC(=O)Cl>>CCOC(=O)C#Cc1cc(Cl)cc(Cl)c1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20100266821A1,COc1cc(C=O)ccc1OCCCCCCCCCCCO.COc1ccc(CC#N)cc1OC>>COc1ccc(C(C#N)=Cc2ccc(OCCCCCCCCCCCO)c(OC)c2)cc1OC,,COC(C)(C)C,,O,[K],test
US05104442,NN.O=C1CCCC(=O)C1C(=O)c1ccccc1[N+](=O)[O-]>>O=C1CCCc2[nH]nc(-c3ccccc3[N+](=O)[O-])c21,,CCO,,O,,test
US20050070441A1,CCN=C=O.Cc1cc(Oc2ccc(Cl)cc2C(F)(F)F)n[nH]1>>CCNC(=O)n1nc(Oc2ccc(Cl)cc2C(F)(F)F)cc1C,,CCOC(C)=O,,CCN(CC)CC,Cl,test
US20090163508A1,Fc1cccc(-c2ccnc(N3CCNCC3)n2)c1.O=C(Nc1cccnn1)OCC(Cl)(Cl)Cl>>O=C(Nc1cccnn1)N1CCN(c2nccc(-c3cccc(F)c3)n2)CC1,,C1CCOC1,CCCCCC,Cl,Cl,test
US20120077828A1,CCI.Nc1ncnc2[nH]nc(I)c12>>CCn1nc(I)c2c(N)ncnc21,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20120208796A1,CI.Cn1c(-c2cccc(Cl)c2)nc2ccc(N3CCN4CCC3CC4)cc2c1=O>>Cn1c(-c2cccc(Cl)c2)nc2ccc(N3CC[N+]4(C)CCC3CC4)cc2c1=O.[I-],,C1CCOC1,,,,test
US20090042891A1,Nc1cncc(-c2cccc(F)c2)n1.O=C1CCC(=O)N1Br>>Nc1cnc(Br)c(-c2cccc(F)c2)n1,,CS(C)=O,O,,,test
US05753664,C1CCN(C2CCNCC2)CC1.Cc1c(OCc2ccc(C(=O)c3ccc(Cl)nc3)cc2)nc2ccccn2c1=O>>Cc1c(OCc2ccc(C(=O)c3ccc(N4CCC(N5CCCCC5)CC4)nc3)cc2)nc2ccccn2c1=O,,c1ccncc1,,,,test
US20120065212A1,COC(=O)c1ncc(OCC2CC2)c(-c2ccc(Cl)cc2)n1>>O=C(O)c1ncc(OCC2CC2)c(-c2ccc(Cl)cc2)n1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US04699915,CCOC(=O)Nc1cccc(-c2csc(NC)n2)c1>>CNc1nc(-c2cccc(N)c2)cs1,,Cl,,Br,[Na+].[OH-],test
US20140080704A1,CCOC(=O)C1=C(/C=C/C2(O)C(C)=CC3(CC2(C)C)OC(C)C(C)O3)CCC1>>CCOC(=O)C1=C(/C=C/C2(O)C(C)=CC(=O)CC2(C)C)CCC1,Cl,CC(C)=O,,O,,test
US20050119489A1,CCc1nn([C@@H]2CCN(C(=O)OC(C)(C)C)C2)c(CC)c1Sc1ccc(F)cc1.Cl>>CCc1nn([C@@H]2CCNC2)c(CC)c1Sc1ccc(F)cc1.Cl,,CCOCC,,,,test
US20120277244A1,CC(C)(C)OC(=O)CNCC(NC(=O)OC(C)(C)C)(c1cc(Br)ccc1F)C(F)F>>O=C1CNCC(c2cc(Br)ccc2F)(C(F)F)N1,,C1COCCO1,ClCCl,Cl,,test
US20050107343A1,CCCCCCCC(=O)Nc1nc(Cl)c2cc(CN3CCCC3)[nH]c2n1.COc1c(C)cnc(CCl)c1C>>COc1c(C)cnc(Cn2c(CN3CCCC3)cc3c(Cl)nc(N)nc32)c1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090005433A1,CS(=O)(=O)Cl.N[C@H](COC(F)F)C(=O)NCc1ccccc1>>CS(=O)(=O)N[C@H](COC(F)F)C(=O)NCc1ccccc1,,CCOC(C)=O,,CCN(CC)CC,,test
US20100298343A1,CCOC(=O)C(Cc1ccc(-c2ccc(C(F)(F)F)cn2)cc1)c1c(SC(C)(C)C)c2cc(O)ccc2n1C.Fc1ccccn1>>CCOC(=O)C(Cc1ccc(-c2ccc(C(F)(F)F)cn2)cc1)c1c(SC(C)(C)C)c2cc(Oc3ccccn3)ccc2n1C,,CS(C)=O,O,[H-].[Na+],,test
US20050054626A1,CCC=C[C@@H]1CC2(CC[C@@H]1NC(=O)[O-])OCCO2>>CCCC[C@@H]1CC2(CC[C@@H]1N)OCCO2,[Pd],CO,,,,test
US20130096113A1,CSc1nc2ccc(CCl)cc2s1.O=c1[nH]ccnc1N1CCOCC1>>CSc1nc2ccc(Cn3ccnc(N4CCOCC4)c3=O)cc2s1,,CN(C)C=O,,O,[H-].[Na+],test
US20020016337A1,CCC(=O)Cl.c1ccc(CN2CCCOC(CNc3ccccc3)C2)cc1>>CCC(=O)Nc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,[Na+].[OH-],test
US20140323435A1,CC(C)c1cc(C(C)C)c(S(=O)(=O)Cl)c(C(C)C)c1.Cc1sc2c(O)nc(-c3ccncc3)nc2c1Br>>Cc1sc2c(OS(=O)(=O)c3c(C(C)C)cc(C(C)C)cc3C(C)C)nc(-c3ccncc3)nc2c1Br,CN(C)c1ccncc1,ClCCl,O,CCN(CC)CC,,test
US08796471B2,CC1(C(=O)Cl)CC1.COC(=O)[C@@H]1C[C@@H](O)CN1.CS(=O)(=O)Cl>>COC(=O)[C@@H]1C[C@@H](OS(C)(=O)=O)CN1C(=O)C1(C)CC1,CN(C)c1ccccn1,ClCCl,,CCN(CC)CC,Cl,test
US20110065707A1,CC(C)c1ccc(NC(=O)C2CCN(C(=O)OC(C)(C)C)CC2)cc1>>CC(C)c1ccc(NC(=O)C2CCNCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090143358A1,CC(C)(C)OC(=O)N1CCC(COCC2CC2)C1>>C1CC(COCC2CC2)CN1,,CC(C)O,,Cl,,test
US20100137280A1,Ic1ccc2[nH]ccc2c1.O=S(=O)(Cl)c1ccc(OC(F)F)cc1>>O=S(=O)(c1ccc(OC(F)F)cc1)n1ccc2cc(I)ccc21,,CN(C)C=O,,O,[H-].[Na+],test
US04503051,COc1c(N)c(=O)c1=O.NCCSc1cccc(CN2CCCCC2)c1>>Nc1c(NCCSc2cccc(CN3CCCCC3)c2)c(=O)c1=O,,CO,,,,test
US20070060607A1,CCOC(=O)c1cnc(Cl)c2c(CBr)csc12.O=[N+]([O-])c1cccc(O)c1>>CCOC(=O)c1cnc(Cl)c2c(COc3cccc([N+](=O)[O-])c3)csc12,,C1CCOC1,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20110280803A1,O=C(O)c1cccc(I)c1.O=C1CCC(=O)N1O>>O=C(ON1C(=O)CCC1=O)c1cccc(I)c1,,CN(C)C=O,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20150284395A1,CC(=O)N(C)C.CCc1nn2c(=O)cc(-c3ccc(Cl)c(OC)c3)[nH]c2c1C(N)=O>>CCc1nn2c(=O)cc(-c3ccc(Cl)c(OC)c3)[nH]c2c1C(=O)/N=C(\C)N(C)C,,CN(C)C=O,,CC(=O)N(C)C,,test
US20160264554A1,C=CC(=O)Cl.CN(Cc1ccc(N)cc1)[C@H]1CCC[C@@H](Nc2ncc(Cl)c(-c3c[nH]c4ccccc34)n2)C1>>C=CC(=O)Nc1ccc(CN(C)[C@H]2CCC[C@@H](Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)C2)cc1,,C1CCOC1,CN1CCCC1=O,CCN(C(C)C)C(C)C,Cl,test
US06114358,CC(=O)CCC(=O)O.CCO>>CCOC(=O)CCC(C)=O,,c1ccccc1,,O,O=S(=O)(O)O,test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc([C@@H](C)N4CCN(S(C)(=O)=O)CC4)cnc3Nc3cnc(OC)c(C(C)C)c3)n2)cc1>>COc1ncc(Nc2ncc([C@@H](C)N3CCN(S(C)(=O)=O)CC3)cc2-c2nc(C)nc(N)n2)cc1C(C)C,,O=C(O)C(F)(F)F,,O=S(=O)(O)C(F)(F)F,,test
US04151360,CC#C[C@@H](C[C@H](C)CCCC(C)C)OC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>CC#C[C@H](O)C[C@H](C)CCCC(C)C,,CO,,[Na+].[OH-],,test
US04230878,C=CCCCCCCCCC=CCCCN(C(=O)OCc1ccccc1)c1ccc(C(=O)Cl)cc1.O=C(O)CC(O)C(=O)O>>C=CCCCCCCCCC=CCCCNc1ccc(C(=O)OC(=O)C(O)CC(=O)O)cc1,[Pd],C1CCOC1,CCOCC,CCN(CC)CC,[H][H],test
US06586447B1,CC(C)(C)OC(=O)C1(C(=O)OC(C)(C)C)C(=O)Nc2cc(Br)ccc21.CN(C)S(=O)(=O)c1ccc(CBr)cc1>>CN(C)S(=O)(=O)c1ccc(CN2C(=O)C(C(=O)OC(C)(C)C)(C(=O)OC(C)(C)C)c3ccc(Br)cc32)cc1,,CN(C)C=O,,[H-].[Na+],,test
US06020342,Cc1ccccc1-c1nc2c3ccccc3ccn2c1N.ClCCOCCCl>>Cc1ccccc1-c1nc2c3ccccc3ccn2c1N1CCOCC1,,CN(C)C=O,,CCCCCC,[H-].[Na+],test
US20090163549A1,CC(=O)c1ccc(C(=O)O)cc1.O=C(Cl)C(=O)Cl>>CC(=O)c1ccc(C(=O)Cl)cc1,,CN(C)C=O,,ClCCl,,test
US20120122838A1,COc1ccc(Cn2cnc3c(N[C@@H](C)c4cc5cccc(Cl)c5c(Cl)n4)ncnc32)cc1.N#C[Zn]C#N>>COc1ccc(Cn2cnc3c(N[C@@H](C)c4cc5cccc(Cl)c5c(C#N)n4)ncnc32)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,,test
US20030055265A1,CCO/C(=C\c1ccc(OCCc2nc(-c3ccccc3)oc2C)c2ccoc12)C(=O)O>>CCOC(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)c2c1OCC2)C(=O)O,[Pd],CO,ClCCl,,,test
US20120040984A1,COC(=O)[C@@H]1CC[C@H](Oc2ccc(C(=O)Nc3nnc(-c4cccc(Cl)c4)s3)cc2)CC1>>O=C(Nc1nnc(-c2cccc(Cl)c2)s1)c1ccc(O[C@H]2CC[C@@H](C(=O)O)CC2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20090247507A1,Fc1cccc(Cl)c1CN1CCNCC1.Nc1ncc(Cl)c(Cl)c1[N+](=O)[O-]>>Nc1ncc(Cl)c(N2CCN(Cc3c(F)cccc3Cl)CC2)c1[N+](=O)[O-],,CC(C)O,,,,test
US20040063708A1,CONC(=O)c1ccc(F)c(N)c1.Cc1cnc(-c2cn3ncnc(Cl)c3c2C(C)C)o1>>CONC(=O)c1ccc(F)c(Nc2ncnn3cc(-c4ncc(C)o4)c(C(C)C)c23)c1,,CCOC(C)=O,CN(C)C=O,,,test
US20110003776A1,C#CCBr.COc1ccc(C#CC[C@@H](O)c2ccccc2)c(C)c1>>C#CCO[C@H](CC#Cc1ccc(OC)cc1C)c1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20110257137A1,N#Cc1ccc(N)c(N)c1.O=C(O)C(=O)O>>N#Cc1ccc2[nH]c(=O)c(=O)[nH]c2c1,,Cl,,,,test
US20110053940A1,COCCCc1cc(CN(C(=O)[C@@H]2CN(C(=O)OC(C)(C)C)CC[C@H]2c2ccn(C)c(=O)c2)C2CC2)cc(-c2ccccc2)c1>>COCCCc1cc(CN(C(=O)[C@@H]2CNCC[C@H]2c2ccn(C)c(=O)c2)C2CC2)cc(-c2ccccc2)c1,,ClCCl,,Cl,,test
US20120238569A1,C#CC(OCC)OCC.O=Cc1ccccc1>>CCOC(C#CC(O)c1ccccc1)OCC,,C1CCOC1,,[Li]CCCC,,test
US05986108,CC(=O)O[C@H]1[C@@H](C(=O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)C(=O)N1N.O=S(=O)(Cl)/C=C/c1ccccc1>>CC(=O)O[C@H]1[C@@H](C(=O)[C@H](Cc2ccccc2)NC(=O)/C=C/c2ccccc2)C(=O)N1N,[Pd],CCOC(C)=O,,CCN(CC)CC,[H][H],test
US20100105744A1,CCC(CCC#N)(c1ccc(Cl)cc1)c1c[nH]c2c(CSC)cccc12.O=C(OO)c1cccc(Cl)c1>>CCC(CCC#N)(c1ccc(Cl)cc1)c1c[nH]c2c(CS(C)=O)cccc12,,CO,,ClCCl,,test
US20110319380A1,O=C1OCCC1=CNc1cc(Br)ccn1>>O=c1c(CCO)cnc2cc(Br)ccn12,O=C(O)C(F)(F)F,O,,Cc1ccccc1C,,test
US20090247596A1,CC(NC(=O)c1sc(Cl)cc1Cc1cccc(Cl)c1)c1ccc(C#N)cc1.CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-]>>CC(NC(=O)c1sc(Cl)cc1Cc1cccc(Cl)c1)c1ccc(-c2nnn[nH]2)cc1,,Cc1ccccc1,,,,test
US20160095858A1,Cc1cc(C)c(Oc2ncc(Br)cc2C(=O)O)c(C)c1.OB(O)c1ccccc1>>Cc1cc(C)c(Oc2ncc(-c3ccccc3)cc2C(=O)O)c(C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20090143420A1,CC(=O)O.Nc1ccc2nc(C(=O)c3ccccc3)cn2c1>>CC(=O)Nc1ccc2nc(C(=O)c3ccccc3)cn2c1,,CC(=O)O,,CC(=O)OC(C)=O,,test
US04279637,CCOC(=O)Nc1ccc(Oc2ccc(OC)cc2)cc1.CNCC(OC)OC>>COc1ccc(Oc2ccc(NC(=O)N(C)CC(OC)OC)cc2)cc1,,Cc1ccccc1,,,,test
US20080194653A1,CC(C)(C)C(=O)NC1=NN(C(=O)C(C)(C)C)C(CNS(=O)(=O)CCl)(c2ccccc2)S1.CC(C)(C)OC(=O)NCCS>>C[SH](CCNC(=O)OC(C)(C)C)S(=O)(=O)NCC1(c2ccccc2)SC(NC(=O)C(C)(C)C)=NN1C(=O)C(C)(C)C,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US20110218182A1,COC(=O)NC1CN(c2c(Cl)cccc2C=O)CCC1C>>CC1CCN(c2c(Cl)cccc2C=O)CC1N,,CO,O,[K+].[OH-],,test
US05130485,C#CCSc1ccccc1C=O.C=C(C)Br>>C#CCSc1ccccc1C(O)C(=C)C,,C1CCOC1,CCCCC,[Li]C(C)(C)C,,test
US06054605,Fc1cc(C(F)(F)F)ccc1Cl.O=C=O>>O=C(O)c1c(C(F)(F)F)ccc(Cl)c1F,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US05346647,CCCCC[C@@H]1CC[C@@H](CCCCc2ccc(-c3ccc(O)cc3)cc2)CC1.CCOC(=O)[C@H](C)O>>CCCCC[C@@H]1CC[C@@H](CCCCc2ccc(-c3ccc(O[C@H](C)C(=O)OCC)cc3)cc2)CC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040167123A1,Nn1c(=O)c(C(=O)Nc2ccc(OCc3ccccc3)cc2S(N)(=O)=O)c(O)c2ccccc21>>Nn1c(=O)c(C2=NS(=O)(=O)c3cc(OCc4ccccc4)ccc3N2)c(O)c2ccccc21,,[K+],[OH-],Cl,,test
US20130331387A1,CCOC(=O)c1sc(Br)cc1Br.OB(O)c1ccc(Cl)cc1>>CCOC(=O)c1sc(-c2ccc(Cl)cc2)cc1Br,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O,O=C([O-])[O-].[K+].[K+],test
US20100152441A1,Cl.OC/C=C/c1cc(F)ccc1F>>Fc1ccc(F)c(/C=C/CCl)c1,,C1COCCO1,,,,test
US06020342,Cc1ccccc1-c1nc2c3cc(OCc4ccccc4)ccc3ccn2c1N>>Cc1ccccc1-c1nc2c3cc(O)ccc3ccn2c1N,[Pd],CCO,,[H][H],,test
US20080027036A1,COc1ccc(Cc2ccccc2)cn1>>Oc1ccc(Cc2ccccc2)cn1,,CC(=O)O,,Br,,test
US08022062B2,CCOC(OCC)c1ccc(C(=O)CC(C)(C)C)cc1>>CC(C)(C)CC(=O)c1ccc(C=O)cc1,,CC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20090131438A1,CCCC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)NN.CN=C=S>>CCCC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)NNC(=S)NC,,CCO,,,,test
US06002008,CCOC(=O)c1cc(OCCOC)c(OCCOC)cc1N.CN(C)C=O>>CCOC(=O)c1cc(OCCOC)c(OCCOC)cc1N=CN(C)C,,ClCCl,,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US20090162283A1,Brc1cnc2[nH]c(-c3ccc(-c4cnco4)cc3)nc2c1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)n1c(-c2ccc(-c3cnco3)cc2)nc2cc(Br)cnc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110098431A1,Cc1ccccc1C(Br)c1ccccc1.Nc1cccc2cccnc12>>Cc1ccccc1C(Nc1cccc2cccnc12)c1ccccc1,,CCN(CC)CC,,,,test
US20060111375A1,COc1cc2nccc(Cl)c2cc1OC.O=C1c2ccccc2-c2ccc(O)cc21>>COc1cc2nccc(Oc3ccc4c(c3)C(=O)c3ccccc3-4)c2cc1OC,CN(C)c1ccncc1,Clc1ccccc1Cl,,O,,test
US20110190281A1,COc1c(OCCCN2CCOCC2)ccc2c1N=C(NC(=O)c1cccnc1)N1CCN=C21>>O=C(NC1=Nc2c(ccc(OCCCN3CCOCC3)c2O)C2=NCCN12)c1cccnc1,,CN1CCCC1=O,,,,test
US06416746B1,C#CCBr.COc1cc2c(cc1O)C(C)(C)CC2=O>>C#CCOc1cc2c(cc1OC)C(=O)CC2(C)C,,CCOC(C)=O,CN1CCCC1=O,O,O=C([O-])[O-].[K+].[K+],test
US20100249163A1,COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(OCc2c[nH]nn2)c2ccc(F)c(F)c2)C2CC2)cc(OCCOC)c1>>COCCCc1cc(CN(C(=O)[C@H]2CNCC[C@]2(OCc2cnn[nH]2)c2ccc(F)c(F)c2)C2CC2)cc(OCCOC)c1,,ClCCl,,Cl,,test
US20070191447A1,CN(C(=O)Cn1c(=O)n2c3c(cccc31)CC(NC(=O)OC(C)(C)C)C2)c1ccccc1.Cl>>CN(C(=O)Cn1c(=O)n2c3c(cccc31)CC(N)C2)c1ccccc1.Cl,,C1COCCO1,,,,test
US20160068513A1,CC(C)c1cc(Nc2nc(N3CCC[C@H]3C(=O)Nc3cccnc3)nc3c2CCC3)n[nH]1.O=C(OO)c1cccc(Cl)c1>>CC(C)c1cc(Nc2nc(N3CCC[C@H]3C(=O)Nc3ccc[n+]([O-])c3)nc3c2CCC3)n[nH]1,,ClCCl,,,,test
US20140296246A1,CCOc1nc2c(C=O)cc(-c3c(C)noc3C)cc2n1C(=O)OC(C)(C)C.Fc1cccc(F)c1>>CCOc1nc2c(C(=O)c3c(F)cccc3F)cc(-c3c(C)noc3C)cc2n1C(=O)OC(C)(C)C,,C1CCOC1,,[Li]CCCC,,test
US05942517,CC(=O)CC(=O)OCc1ccccc1.O=Cc1ccc2c(c1)OCO2>>CC(=O)C(=Cc1ccc2c(c1)OCO2)C(=O)OCc1ccccc1,,CC(C)O,,C1CCNCC1,CC(=O)O,test
US20040127574A1,NC(Cc1ccccc1C(F)(F)F)C(O)c1ccc(F)cc1.O=C(Cl)C1CCCCC1>>O=C(NC(Cc1ccccc1C(F)(F)F)C(O)c1ccc(F)cc1)C1CCCCC1,,CCOC(C)=O,O,O=C([O-])O.[Na+],,test
US20090275537A1,CN(C(=O)NCc1cccc(F)c1Cl)[C@@H](CNC(=O)CNC(=O)OC(C)(C)C)COC(=O)Nc1cc2cc(F)ccc2cn1>>CN(C(=O)NCc1cccc(F)c1Cl)[C@@H](CNC(=O)CN)COC(=O)Nc1cc2cc(F)ccc2cn1,,ClCCl,,Cl,O=C(O)C(F)(F)F,test
US20020183320A1,COc1ccccc1C=O.Nc1nccs1.[C-]#[N+]C(C)(C)C>>COc1ccccc1-c1nc2sccn2c1NC(C)(C)C,,[O-][Cl+3]([O-])([O-])O,,,,test
US20040087593A1,C1CNCCN1.O=S(=O)(c1ccc(Cl)cc1)n1ccc2cc(F)ccc21>>O=S(=O)(c1ccc(N2CCNCC2)cc1)n1ccc2cc(F)ccc21,,CS(C)=O,O,,,test
US20110281865A1,CC(=O)c1ccc2nnn(Cc3ccc4ncccc4c3)c2n1.NNC(N)=O>>CC(=NNC(N)=O)c1ccc2nnn(Cc3ccc4ncccc4c3)c2n1,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20090018132A1,C=O.Cn1cc2cc(C(F)(F)F)cc(COCC3(c4ccccc4)CCNCC3)c2n1>>CN1CCC(COCc2cc(C(F)(F)F)cc3cn(C)nc23)(c2ccccc2)CC1,CC(=O)O,CC#N,,[BH3-]C#N.[Na+],,test
US20040082779A1,COc1ccc(Br)cc1CCc1c(Cl)cccc1C#N>>N#Cc1cccc(Cl)c1CCc1cc(Br)ccc1O,,ClCCl,,BrB(Br)Br,,test
US20130203776A1,CCOC(=O)c1cnn2ccc(N3CC(O[Si](C)(C)C(C)(C)C)C[C@@H]3c3cc(F)ccc3OC)nc12>>CCOC(=O)c1cnn2ccc(N3CC(O)C[C@@H]3c3cc(F)ccc3OC)nc12,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130053409A1,C=CC(=O)Nc1cc(Nc2nccc(-c3cn(C)c4ccccc34)n2)c(OC)cc1N(C)CCN(C)C(=O)OC(C)(C)C>>C=CC(=O)Nc1cc(Nc2nccc(-c3cn(C)c4ccccc34)n2)c(OC)cc1N(C)CCNC,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110275611A1,O=C(N[C@@H]1CCCC[C@H]1O)C1CN(Cc2ccccc2)CCO1>>O=C(N[C@@H]1CCCCC1=O)C1CN(Cc2ccccc2)CCO1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20070244125A1,FC1CCNC(F)C1.O=C(O)c1cc2cc(Br)cc(Cl)c2[nH]1>>O=C(c1cc2cc(Br)cc(Cl)c2[nH]1)N1CCC(F)(F)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20110166133A1,CCCC[Sn](CCCC)(CCCC)c1cccc(C2(C)OCCO2)n1.Fc1ccc(F)c(C2CCCN2c2ccc3ncc(Br)n3n2)c1>>CC1(c2cccc(-c3cnc4ccc(N5CCC[C@@H]5c5cccc(F)c5)nn34)n2)OCCO1,,Cc1ccccc1,,,,test
US20130190315A1,O=S(Cl)Cl.OCc1cccnc1-c1ccnn1CC(F)(F)F>>Cl.FC(F)(F)Cn1nccc1-c1ncccc1CCl,,ClCCl,,,,test
US20160207922A1,Cc1c([C@@H]2CO2)ccc2c1COC2=O.N#Cc1ccc(N2CCC3(CCNCC3)C2=O)nc1>>Cc1c([C@@H](O)CN2CCC3(CC2)CCN(c2ccc(C#N)cn2)C3=O)ccc2c1COC2=O,,CC(C)O,O,O=C(O)C(F)(F)F,,test
US04652551,CC(C)CC(NC(=O)OC(C)(C)C)C(O)CCc1ccccc1.Cl>>CC(C)CC(N)C(O)CCc1ccccc1.Cl,,CO,,,,test
US20050288286A1,CCOC(=O)CCc1cccc(-n2nc(C(C)(C)C)cc2NC(=O)c2ccc(Cl)cc2)c1>>CC(C)(C)c1cc(NC(=O)c2ccc(Cl)cc2)n(-c2cccc(CCC(=O)O)c2)n1,,CO,,[Li+].[OH-],,test
US20050101643A1,CCC[C@@H](C)[C@@H](C)C(=O)N1C(=O)OC[C@H]1c1ccccc1>>CCC[C@@H](C)[C@@H](C)CO,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050192347A1,CC(CO)(CCCCN1C(=O)c2ccccc2C1=O)c1ccccc1>>CC(CO)(CCCCN)c1ccccc1,,CCO,,NN,O,test
US20070185136A1,COc1cccc(C(=O)c2cc(Cl)ccc2N)c1>>COc1cccc(C(O)c2cc(Cl)ccc2N)c1,,CCO,,[BH4-].[Na+],,test
US20120245209A1,O=S(=O)(Nc1c(Nc2ccc(I)cc2F)c(F)c(F)c2ncoc12)C1CC1COCc1ccccc1>>O=S(=O)(Nc1c(Nc2ccc(I)cc2F)c(F)c(F)c2ncoc12)C1CC1CO,,ClCCl,,ClB(Cl)Cl,,test
US20030055085A1,C[Sn](C)(C)c1ccc(C#N)cn1.N#Cc1cccc(-c2ccc(Br)o2)c1>>N#Cc1ccc(-c2ccc(-c3cccc(C#N)c3)o2)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20030203944A1,COc1cc(OCC(C)O)ccc1O[Si](C)(C)C(C)(C)C.S=C=NCCc1ccccc1>>COc1cc(OCC(C)OC(=S)NCCc2ccccc2)ccc1O[Si](C)(C)C(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20150175621A1,N#Cc1ccc(Br)cn1.[Li]OS(=O)c1ccc(NC(=O)OC(C)(C)C)nc1>>N#Cc1ccc(S(=O)(=O)c2ccc(N)nc2)cn1,,CS(C)=O,,,,test
US20140011800A1,CC(C)(C)OC(=O)N1CC[C@@H](Nc2c(C(N)=O)cnn3cc(C(=O)NN)cc23)C(C)(C)C1.CI.S=C(n1ccnc1)n1ccnc1>>CSc1nnc(-c2cc3c(N[C@@H]4CCN(C(=O)OC(C)(C)C)CC4(C)C)c(C(N)=O)cnn3c2)o1,,C1CCOC1,,CCN(CC)CC,,test
US20080194546A1,CC(=O)OC(C)=O.C[C@H]1COCCN1c1nc(N2CCOC[C@@H]2C)c2ccc(-c3ccnc(N)c3)nc2n1>>CC(=O)Nc1cc(-c2ccc3c(N4CCOC[C@@H]4C)nc(N4CCOC[C@@H]4C)nc3n2)ccn1,,c1ccncc1,,,,test
US20090275606A1,CC(C)(C)OC(=O)N1CCCCC1C1(O)CN(C(=O)c2c(Nc3ccc(Br)cc3F)c(F)c(=O)n3c2CCC3)C1>>O=C(c1c(Nc2ccc(Br)cc2F)c(F)c(=O)n2c1CCC2)N1CC(O)(C2CCCCN2)C1,,CO,Cl,C1COCCO1,,test
US20070135385A1,COc1nccc2c1cc(C)n2Cc1ccccc1-c1ccccc1>>Cc1cc2c(=O)[nH]ccc2n1Cc1ccccc1-c1ccccc1,,Br,CC(=O)O,,,test
US20070219193A1,COC(=O)Cc1ccc2c(c1)CN(C(=O)C(F)(F)F)CC2>>COC(=O)Cc1ccc2c(c1)CNCC2,,CO,,[BH4-].[Na+],,test
US20100093698A1,N#Cc1nc2ccc(-c3cccc4nc(Nc5ccc(C(F)(F)F)cc5)nn34)cc2[nH]1>>N#Cc1nc2ccccc2[nH]1,,N,,,,test
US20130225524A1,COC(=O)c1ccc([N+](=O)[O-])cc1C(=O)OC.Cc1noc(C)c1-c1ccc2c(Cl)c(C(N)=O)cnc2c1>>COC(=O)c1ccc(Nc2c(C(N)=O)cnc3cc(-c4c(C)noc4C)ccc23)cc1C(=O)OC,[Pd],CC(=O)O,,,,test
US04035376,CCOC(=O)C(C)c1ccc(C(=O)c2cccs2)cc1.NO>>CC(C(=O)NO)c1ccc(C(=O)c2cccs2)cc1,,CO,,Cl,[K+].[OH-],test
US04772312,CCOC(=O)c1cnn(-c2ccc(C(F)(F)F)cn2)c1N>>Nc1c(C(=O)O)cnn1-c1ccc(C(F)(F)F)cn1,,CCO,,[Na+].[OH-],,test
US20100016337A1,C1CCNCC1.CCOC(=O)CC(C)(C)c1csc(-c2ccc(C(F)(F)F)cc2)n1>>CC(C)(CC(=O)N1CCCCC1)c1csc(-c2ccc(C(F)(F)F)cc2)n1,,CN(C)C=O,,[H-].[Na+],,test
US06207697B1,CC(=O)Nc1ccc(C#N)cc1N.O=C1N=c2ccccc2=N1>>CC(=O)n1c(=O)[nH]c2cc(C#N)ccc21,,CC#N,,,,test
US04093742,CCN=C=O.CNc1c(C)cc(C(O)(C(F)(F)F)C(F)(F)F)cc1C>>CCNC(=O)N(C)c1c(C)cc(C(O)(C(F)(F)F)C(F)(F)F)cc1C,,CCOCC,,,,test
US20040225137A1,COCOC.Cl.O=[N+]([O-])c1ccc(O)cc1>>O=[N+]([O-])c1ccc(O)c(CCl)c1,,O=S(=O)(O)O,,,,test
US20160009744A1,Cc1sc(CO)cc1Cc1cccc(Cl)c1>>Cc1sc(C=O)cc1Cc1cccc(Cl)c1,O=[Mn]=O,ClCCl,,,,test
US05859007,Brc1cccnc1.CC(C)N(C(=O)CN1C(=O)CC(=O)Nc2ccccc21)c1ccccc1>>CC(C)N(C(=O)CN1C(=O)CC(=O)N(c2cccnc2)c2ccccc21)c1ccccc1,[Cu],CCOC(C)=O,CN(C)C=O,CC(=O)[O-].[K+],,test
US20150291549A1,Cc1cc(C=O)c(O)cc1OCc1cccc(-c2ccc3c(c2)OCCO3)c1C.N#Cc1cncc(CCl)c1>>Cc1cc(C=O)c(OCc2cncc(C#N)c2)cc1OCc1cccc(-c2ccc3c(c2)OCCO3)c1C,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20150111935A1,CCCCCCC/C=C/C=C/C(=O)O.O=C(Cl)C(=O)Cl>>CCCCCCC/C=C/C=C/C(=O)Cl,,ClCCl,,,,test
US20060004046A1,CS(=O)(=O)c1cnc2ccc(C=O)cc2c1-c1ccccc1.O=C1CSC(=S)N1>>CS(=O)(=O)c1cnc2ccc(C=C3SC(=S)NC3=O)cc2c1-c1ccccc1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20040192735A1,OCc1nn(C2CCCCO2)c2cc(Cl)ccc12>>O=Cc1nn(C2CCCCO2)c2cc(Cl)ccc12,,CCOC(C)=O,O,CS(C)=O,,test
US20150203511A1,BrCCBr.Cc1cc(-c2n[nH]c(O)c2C)ccc1OC(C)C>>Cc1cc(-c2nn3c(c2C)OCC3)ccc1OC(C)C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090124625A1,Cn1c(CCC#C[Si](C)(C)C)nc2ccccc21>>C#CCCc1nc2ccccc2n1C,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20140005213A1,CC(C)I.Cc1ccc2ccc(O)c(C)c2n1>>Cc1ccc2ccc(OC(C)C)c(C)c2n1,,CC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160145247A1,COC(=O)Cc1ccccc1OCc1cc(Cl)cc(C(NS(=O)C(C)(C)C)C(F)(F)F)c1>>COC(=O)Cc1ccccc1OCc1cc(Cl)cc(C(N)C(F)(F)F)c1,,CO,,C1COCCO1,Cl,test
US20040167155A1,COc1ccc(S(=O)(=O)NC(C)c2ccccc2-c2cc(F)ccc2F)cc1>>COc1ccc(S(=O)(=O)N2c3ccc(F)cc3-c3ccccc3C2C)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140275015A1,CC(C)(C)ON=O.Cc1cc(Nc2ccccn2)c(N)cn1>>Cc1cc2c(cn1)nnn2-c1ccccn1,,C1CCOC1,,CC(=O)O,,test
US05608069,CCCCCCC/C(=N\OCCN1CCC[C@@H](C(=O)OCC)C1)c1ccccc1.Cl>>CCCCCCC/C(=N\OCCN1CCC[C@@H](C(=O)O)C1)c1ccccc1.Cl,,CCO,,[Na+].[OH-],,test
US20120264823A1,C=CCOc1ccc([C@@H]2C[C@H]2NC(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1ccc(O)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,[BH4-].[Li+],,test
US05276038,Nc1ccccc1C(=O)O.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=c1oc(C(F)(F)F)nc2ccccc12,,CC(=O)OC(C)=O,,,,test
US05114939,Fc1cccc2c(Cl)ccnc12.NCCc1cccs1>>Fc1cccc2c(NCCc3cccs3)ccnc12,,O,,[NH4+].[OH-],,test
US20140011819A1,CC(Br)c1oc2ccccc2c(=O)c1-c1cccc(F)c1.CS(C)=O>>CC(O)c1oc2ccccc2c(=O)c1-c1cccc(F)c1,,CCCCO,,,,test
US20120059028A1,CCCI.COC(=O)Cc1c(C)nc2sc3c(c2c1-c1cccs1)CCC3>>CCCC(C(=O)OC)c1c(C)nc2sc3c(c2c1-c1cccs1)CCC3,,CN(C)C=O,,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20080009486A1,CCOC(=O)N1C(=O)C2(c3ccc(Cl)cc31)C(c1cccc(Cl)c1)CC(=O)NC2c1cccc(F)c1C>>Cc1c(F)cccc1C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12,,CO,,[Na+].[OH-],,test
US20110230476A1,CC(C)(C)OC(=O)N1CCNCC1.COC(=O)c1ccc2nccc(Cl)c2c1>>COC(=O)c1ccc2nccc(N3CCN(C(=O)OC(C)(C)C)CC3)c2c1,,CC(C)O,,,,test
US20120238763A1,N#C[C@]1(N)[C@H](OCc2ccc(Cl)c(Cl)c2)C[C@@H]2[C@H]1[C@@]2(F)C(N)=O.OO>>NC(=O)[C@]1(N)[C@H](OCc2ccc(Cl)c(Cl)c2)C[C@@H]2[C@H]1[C@@]2(F)C(N)=O,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090018147A1,COc1c(O)cccc1C=O.Cc1nc2ccccc2c(=O)n1-c1ccccc1>>COc1c(O)cccc1C=Cc1nc2ccccc2c(=O)n1-c1ccccc1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20050004134A1,CC(C)N.CCOC(=O)c1nc(-c2cccc(Cl)c2)c(-c2ccc(=O)n(C(C)C)n2)s1>>CC(C)NC(=O)c1nc(-c2cccc(Cl)c2)c(-c2ccc(=O)n(C(C)C)n2)s1,,C1CCOC1,,,,test
US04759869,CC[C@H](C)CCCCCOS(=O)(=O)c1ccc(C)cc1.Oc1ccc(OCc2ccccc2)cc1>>CC[C@H](C)CCCCCOc1ccc(OCc2ccccc2)cc1,,CCO,O,[Na+].[OH-],,test
US04774365,C=C(C)C.COC(C)(C)C>>C=C(C)C.COC(C)(C)C,,CO,,,,test
US20150087828A1,COc1ccc(CNCCO)cc1.O=CC(=O)O>>COc1ccc(CN2CCOC(O)C2=O)cc1,,C1CCOC1,,O,,test
US20140213586A1,COc1ccc(C=O)cn1.COc1cncc(N)n1>>COc1ccc(C=Nc2cncc(OC)n2)cn1,,CCO,,,,test
US20130183704A1,COC(=O)CN(CCCc1ccccc1)C(=O)CCCCc1ccccc1>>O=C(O)CN(CCCc1ccccc1)C(=O)CCCCc1ccccc1,,CCOC(C)=O,CO,Cl,[Na+].[OH-],test
US20080045526A1,C1COCCN1.CCC1OC(=C2C(=O)Nc3ccccc32)c2cnc(Cl)cc21>>CCC1OC(=C2C(=O)Nc3ccccc32)c2cnc(N3CCOCC3)cc21,,CC(C)O,,,,test
US20090012308A1,BrCc1ccc2ccccc2c1.O=S([O-])c1ccc(Cl)cc1>>O=S(=O)(Cc1ccc2ccccc2c1)c1ccc(Cl)cc1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US04160837,C1=CCN(Cc2ccccc2)C1.O=C(Cl)OCC(Cl)(Cl)Cl>>O=C(OCC(Cl)(Cl)Cl)N1CC=CC1,,c1ccccc1,,,,test
US20130072490A1,CCOC(=O)C1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1ccccc1N1CCN(C(=O)c2c(C)noc2-c2ccc(Br)cc2)CC1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4C(=O)N4CCN(c5ccccc5C)CC4)cc3)cc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])O.[Na+],,test
US20160158207A1,CCC1=Cc2ccccc2NC1>>CCC1CNc2ccccc2C1,[Pd],CO,,,,test
US20040229924A1,CC#CCOc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(C(=O)C3(C)COC(C)(C)OC3)CC2)cc1>>CC#CCOc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(C(=O)C(C)(CO)CO)CC2)cc1,,C1CCOC1,,Cl,,test
US20020013460A1,CCCC(=O)c1ccc(-c2cc3ccccc3c(N3CCN(CC)CC3)n2)cc1.NO>>CCCC(=NO)c1ccc(-c2cc3ccccc3c(N3CCN(CC)CC3)n2)cc1,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20150232481A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc(C=O)nn2c1N1CCC(C)(OCCCC[C@@H](C)O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)CC1.Fc1cc(F)c(OCc2ccccc2)c(CC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc(C=CCc3cc(F)cc(F)c3OCc3ccccc3)nn2c1N1CCC(C)(OCCCC[C@@H](C)O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)CC1,,C1CCOC1,,[H-].[Na+],,test
US05192766,CC(C)CBr.CCOC(=O)/C=C/c1ccc(O)cc1>>CCOC(=O)/C=C/c1ccc(OCC(C)C)cc1,,CS(C)=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US05472964,Cc1ccc2oc(Cl)c(Cl)c2n1>>Cc1ccc2occ(Cl)c2n1,,C1CCOC1,,[Li]C(C)(C)C,,test
US20160045505A1,Cc1ccc(C(=O)Cl)o1.Nc1ccc(Cl)c(-c2cn3cc(Br)cnc3n2)c1>>Cc1ccc(C(=O)Nc2ccc(Cl)c(-c3cn4cc(Br)cnc4n3)c2)o1,CN(C)c1ccncc1,CO,c1ccncc1,,,test
US20020055527A1,Cc1ncsc1CO.O=C(CCl)c1ccccc1>>Cc1c(CO)sc[n+]1CC(=O)c1ccccc1.[Cl-],,COC(C)(C)C,,CC#N,,test
US20130317031A1,CN1CCC(C(=O)NN)CC1.O=C(O)/C=C\n1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1>>CN1CCC(C(=O)NNC(=O)/C=C\n2cnc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)CC1,,C1CCOC1,CCOC(C)=O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20100190745A1,CCOC(=O)/C(=C\N(C)C)C(=O)c1cc(I)ccc1F.N[C@H]1CCCC[C@@H]1N>>CCOC(=O)c1cn([C@H]2CCCC[C@@H]2N)c2ccc(I)cc2c1=O,,O,,O=C([O-])[O-].[K+].[K+],,test
US20120316161A1,CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1Cl.Cc1ccc(B(O)O)c(F)c1>>CCCC(C(=O)OC)c1c(C)nc2cc(C(C)(C)C)nn2c1-c1ccc(C)cc1F,,COCCOC,O,CCN(C(C)C)C(C)C,,test
US04354970,CC1(C)CC(=O)c2sc(N)nc2C1.O=C(CBr)c1ccccc1>>CC1(C)CC(=O)c2sc3nc(-c4ccccc4)cn3c2C1,,ClC(Cl)Cl,,,,test
US20070219181A1,COC(=O)Cc1ccccc1.ClCCCI>>COC(=O)C(CCCCl)c1ccccc1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US05420130,COc1ccc(Cl)cc1N1CCN(CCCNc2cnc(C(=O)NCCNC(=O)OC(C)(C)C)cn2)CC1>>COc1ccc(Cl)cc1N1CCN(CCCNc2cnc(C(=O)NCCN)cn2)CC1,,O,,Cl,[Na+].[OH-],test
US20090270430A1,CCNc1nc(C)cc(NC2CCCCC2)n1.O=C1CCC(=O)N1I>>CCNc1nc(C)c(I)c(NC2CCCCC2)n1,,CC#N,,,,test
US04634705,C=CCBr.COc1c(O)cccc1F>>C=CCOc1cccc(F)c1OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050049245A1,CCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CCl)sc21.CNC[C@@H](O)c1ccco1>>CCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN(C)C[C@@H](O)c3ccco3)sc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20090143592A1,COC(=O)CCNC(=O)c1ccc(C(NC(=O)Nc2ccc(OC(F)(F)F)cc2)C2CCN(C(=O)C3CC3)CC2)cc1>>O=C(O)CCNC(=O)c1ccc(C(NC(=O)Nc2ccc(OC(F)(F)F)cc2)C2CCN(C(=O)C3CC3)CC2)cc1,,CCO,O,[Li+].[OH-],,test
US20070054916A1,COCC(=O)Nc1ccc(C(F)(F)F)cc1[N+](=O)[O-]>>COCC(=O)Nc1ccc(C(F)(F)F)cc1N,[Pd],CCOC(C)=O,CO,,,test
US20150225449A1,Cc1cnc2ccccc2c1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)[C@H](C)N(C(=O)CS(C)(=O)=O)c2ccccc21.Cl>>CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(C)cnc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C.Cl,,C1COCCO1,CCOCC,,,test
US20090325988A1,C#CCC(O)(CC(C)(C)c1ccccc1C(=O)O)C(F)(F)F.C[Si](C)(C)Cl>>C#CCC(CC(C)(C)c1ccccc1C(=O)O)(O[Si](C)(C)C)C(F)(F)F,,CCOCC,CN(C)C=O,c1c[nH]cn1,,test
US20160102058A1,Cl[Mg]C1CCCCC1.O=CC1CCC2(CC1)OCCO2>>OC(C1CCCCC1)C1CCC2(CC1)OCCO2,,C1CCOC1,,,,test
US05474998,CC(=O)c1ccc(Cl)s1.C[Mg]Br>>C=C(C)c1ccc(Cl)s1,,CCOCC,,[Cl-].[NH4+],,test
US20150152050A1,CC(C)(C)OC(=O)/C=C/c1ccc(Cl)c([N+](=O)[O-])c1>>CC(C)(C)OC(=O)CCc1ccc(Cl)c(N)c1,[Pd],CCOC(C)=O,,,,test
US04279637,COC(CN(C)C(=O)Nc1ccc(Oc2ccc(Cl)c(Cl)c2)cc1)OC>>Cn1ccn(-c2ccc(Oc3ccc(Cl)c(Cl)c3)cc2)c1=O,,O,,Cl,,test
US20120065396A1,COc1cc2c(c(Br)c1OC)CN(Cc1ccc(C(=O)O)cc1)C2=O.Nc1ccccc1N>>COc1cc2c(c(Br)c1OC)CN(Cc1ccc(C(=O)Nc3ccccc3N)cc1)C2=O,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US05849753,CCCCc1nc2nc(CO)c(Br)cc2[nH]1.O=C(CBr)c1ccccc1>>CCCCc1nc2cc(Br)c(CO)nc2n1CC(=O)c1ccccc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US06403594B1,COc1ccc(C#N)cc1[N+](=O)[O-]>>COc1ccc(C#N)cc1N,,CCO,,,,test
US05789409,COC(=O)Cc1ccc(CBr)cc1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>COC(=O)Cc1ccc(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1,,C1COCCO1,,CCN(CC)CC,,test
US20080312192A1,Cc1cc(Oc2ccnc(NCCCCN(C)C)n2)ccc1NC(=O)Nc1ccc(-c2cccc(Cl)c2)c(C(F)(F)F)c1.OB(O)c1cccc(Br)c1>>Nc1ccc(-c2cccc(Br)c2)c(C(F)(F)F)c1,,CCCCCC,CCOC(C)=O,,,test
US20110021532A1,CO.CSc1ccc2nc(-c3ccc(-c4ccccc4F)cc3)[nH]c2c1>>CS(=O)c1ccc2nc(-c3ccc(-c4ccccc4F)cc3)[nH]c2c1,,O,,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US04297129,Cc1ccc(C(=O)OCn2ncc(=O)[nH]c2=O)cc1>>Cc1ccc(C(=O)OCN2NCC(=O)NC2=O)cc1,O=[Pt],CCO,,[H][H],,test
US07495106B1,CCBr.O=C(O)c1ccc(-c2nc3ccccc3s2)cc1>>CCOC(=O)c1ccc(-c2nc3ccccc3s2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080194536A1,C[C@H](N)C(=O)N(C)C.N#Cc1ccc(F)cc1C(F)(F)F>>C[C@H](Nc1ccc(C#N)c(C(F)(F)F)c1)C(=O)N(C)C,,CCOCC,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100190747A1,CC(C)OCC1CO1.O=c1c2[nH]ccc2[nH]c(=S)n1-c1ccc(OCC(F)(F)F)cc1>>CC(C)OCC(O)CSc1nc2cc[nH]c2c(=O)n1-c1ccc(OCC(F)(F)F)cc1,,CN(C)C=O,,CCN(CC)CC,[I-].[Na+],test
US20010039285A1,COc1ccc2c(c1)CCNC2C1CCN(S(=O)(=O)c2cn(C)cn2)CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccc2c(c1)CCN(C(=O)C(F)(F)F)C2C1CCN(S(=O)(=O)c2cn(C)cn2)CC1,,ClCCl,,CCN(CC)CC,,test
US20070207997A1,CN(C)S(=O)(=O)Cl.NC(=O)c1cc2c(nc1N)[nH]c1ccccc12>>CN(C)S(=O)(=O)n1c2ccccc2c2cc(C(N)=O)c(N)nc21,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US05250669,CCO.O=C(Cl)C1CCCCC1>>CCOC(=O)C1CCCCC1,,Cc1ccccc1,O,CCN(CC)CC,Cl,test
US20110034433A1,CC1=C(C#N)[C@@H](c2ccc(C#N)cc2S(C)(=O)=O)N(CC(=O)O)C(=O)N1c1cccc(C(F)(F)F)c1.OC1CCNCC1>>CC1=C(C#N)[C@@H](c2ccc(C#N)cc2S(C)(=O)=O)N(CC(=O)N2CCC(O)CC2)C(=O)N1c1cccc(C(F)(F)F)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04036977,CC#CCBr.CNc1ccc(OC23CC4CC(CC(C4)C2)C3)cc1>>CC#CCN(C)c1ccc(OC23CC4CC(CC(C4)C2)C3)cc1,,c1ccccc1,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20040110802A1,CC(C)(C)OC(=O)c1ccccc1N.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)c1cc(Br)ccc1N,,CN(C)C=O,,,,test
US20160002169A1,CCOC(=O)C1c2ccc(O)cc2CCN1C(=O)OC(C)(C)C.CI>>CCOC(=O)C1c2ccc(OC)cc2CCN1C(=O)OC(C)(C)C,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20150189884A1,CS(=O)(=O)OCc1ccc(C2=NCC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1Br.N>>NCc1ccc(C2=NCC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1Br,,C1CCOC1,CO,,,test
US20070167433A1,CC(C)[Mg]Br.COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CC(O[Si](C(C)C)(C(C)C)C(C)C)C3c3ccc(C=O)cc3)cc21>>COCCCN1CCOc2ccc(COC3CN(C(=O)OCc4ccccc4)CC(O[Si](C(C)C)(C(C)C)C(C)C)C3c3ccc(C(O)C(C)C)cc3)cc21,,C1CCOC1,,,,test
US20160002204A1,CCOC(=O)c1cn(CCC(F)Cn2ccc(NC(=O)Cc3ccccc3)cc2=O)nn1>>O=C(Cc1ccccc1)Nc1ccn(CC(F)CCn2cc(C(=O)O)nn2)c(=O)c1,,C1CCOC1,CO,[Li+].[OH-],,test
US20130172342A1,CCCOc1ccc([N+](=O)[O-])c(NC(=O)CC2CCCCN2)c1>>CCCOc1ccc(N)c(NC(=O)CC2CCCCN2)c1,[Pd],CCO,,,,test
US04600775,NNC(=O)c1cccc(N)c1C(=O)NN.O=C1C=CC(=O)O1>>NC(=O)/C=C\C(=O)O.Nc1cccc2c(=O)[nH][nH]c(=O)c12,,CC(=O)O,,,,test
US05314885,C1CCNC1.C1CCOC1.CC(C)Oc1ccccc1N1CCN(Cc2ccc(CCl)cc2)CC1.CCN(CC)CC>>CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCC3)cc2)CC1.[NH4+].[OH-],,ClCCl,,Cl,,test
US20070232583A1,CNC.O=S(=O)(Cl)c1cccc(-c2cc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)(F)F)n3)ccn2)c1>>CN(C)S(=O)(=O)c1cccc(-c2cc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)(F)F)n3)ccn2)c1,,C1CCOC1,,CCN(CC)CC,Cl,test
US20020013310A1,Cc1ccc(C#N)c(N=Cc2ccccc2)c1.O=C1CCC(=O)N1Br>>N#Cc1ccc(CBr)cc1N,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20140018365A1,CC(C)(C)OC(=O)NCCCBr.COc1cc2c(Oc3ccc([N+](=O)[O-])cc3F)ccnc2cc1O>>COc1cc2c(Oc3ccc([N+](=O)[O-])cc3F)ccnc2cc1OCCCNC(=O)OC(C)(C)C,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US08877747B2,CS(=O)(=O)Cl.Cc1ccc(C2=C(c3cc(F)cc(F)c3)c3ccc(OCCCN4CCNCC4)cc3C2=O)cc1>>Cc1ccc(C2=C(c3cc(F)cc(F)c3)c3ccc(OCCCN4CCN(S(C)(=O)=O)CC4)cc3C2=O)cc1,,ClCCl,,CCN(CC)CC,,test
US20100105655A1,CNCCN(C)c1ccc([N+](=O)[O-])c(OC)c1.O=C(O)CO>>COc1cc(N(C)CCN(C)C(=O)CO)ccc1[N+](=O)[O-],,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090247559A1,CC(C)(C)OC(=O)N1CCC(CO)C1.O=c1[nH]c(C2CCCN2)nc2c1oc1ccc(Br)cc12>>O=c1[nH]c(CN2CCC(CO)C2)nc2c1oc1ccc(Br)cc12,,C1COCCO1,CCOC(C)=O,CCN(CC)CC,Cl,test
US20120214837A1,CC(=O)NCCNc1nc2ccc(OCC3CC3)cc2cc1CCl.CCCc1nc(O)cc2cc(OC)c(OC)cc12>>CCCc1nc(O)c(Cc2cc3cc(OCC4CC4)ccc3nc2NCCNC(C)=O)c2cc(OC)c(OC)cc12,,C1CCOC1,,Cl,[Li+].[OH-],test
US20100249123A1,CC(C)(C#N)c1ccc(N)cc1.COc1ccc(C(=O)O)c(Cl)c1OC>>COc1ccc(C(=O)Nc2ccc(C(C)(C)C#N)cc2)c(Cl)c1OC,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US05952386,CCOC(=O)CC(C)Br.Oc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl>>CCOC(=O)C(CC)Oc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130109566A1,C#CCN(C(=O)OC(C)(C)C)c1cn(-c2cccnc2)nc1Cl>>C#CCNc1cn(-c2cccnc2)nc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070037836A1,CC(C)(C)OC(=O)Nc1ccc(N)cc1.CN(C)c1nc(Cl)nc2ccccc12>>CN(C)c1nc(Nc2ccc(NC(=O)OC(C)(C)C)cc2)nc2ccccc12,,ClCCl,,,,test
US20060014948A1,C[C@H](N)CO.O=Cc1ccccc1>>C[C@@H](CO)NCc1ccccc1,,CC(=O)O,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130210825A1,Cc1nc2cc(-c3ccccc3)c(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)nn2c1-c1cccc(C(N)=O)c1>>Cc1nc2cc(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nn2c1-c1cccc(C(N)=O)c1,,C1COCCO1,,Cl,,test
US06060207,C=CC(=O)O.CC(C)=CCCC(C)CCO>>C=CC(=O)OCCC(C)CCC=C(C)C,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04540692,CN1C(C(=O)Nc2cccccc2=O)=C(OC(=O)C=Cc2ccccc2)c2ccccc2S1(=O)=O>>CN1C(C(=O)Nc2cccccc2=O)=C(O)c2ccccc2S1(=O)=O,,CO,,Cl,[Na+].[OH-],test
US07030063B1,COC(=O)c1ccc(C(F)F)c2ncccc12>>O=C(O)c1ccc(C(F)F)c2ncccc12,,CCO,,O,[Na+].[OH-],test
US20140249129A1,CN(C)C=O.CS(=O)(=O)c1cc(C#N)ccc1C1NC(=O)N(c2ccnc(C(F)(F)F)c2)C2=C1C(=O)CCC2>>CN1C(=O)N(c2ccnc(C(F)(F)F)c2)C2=C(C(=O)CCC2)C1c1ccc(C#N)cc1S(C)(=O)=O,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US04163844,CC(C)(N)CS.O=C(O)Cc1ccccc1C(=O)O>>CC1(C)CSc2cc3ccccc3c(=O)n21,,Clc1ccccc1Cl,,CC(=O)[O-].[Na+],,test
US20050009829A1,CC(C)N1CCC(NC(=O)c2nc3c(CO)cccc3n2CC(=O)Nc2ccc(Cl)cn2)CC1.COCCBr>>COCCOCc1cccc2c1nc(C(=O)NC1CCN(C(C)C)CC1)n2CC(=O)Nc1ccc(Cl)cn1,,CN(C)C=O,,,,test
US20020028938A1,CC(C)CCc1c(-c2ccc(S(C)(=O)=O)cc2)cnn(-c2ccc(F)c(Cl)c2)c1=O.N>>CC(C)CCc1c(-c2ccc(S(N)(=O)=O)cc2)cnn(-c2ccc(F)c(Cl)c2)c1=O,,O,,,,test
US20080269196A1,CC(C)(C)CS(=O)(=O)Cc1ccc(CNc2c(Cl)ccc3c2CCN(C(=O)C(F)(F)F)CC3)cc1>>CC(C)(C)CS(=O)(=O)Cc1ccc(CNc2c(Cl)ccc3c2CCNCC3)cc1,,CO,,O,[Li]O,test
US20110269738A1,CCc1c(/C=C/OC)cccc1-c1nsc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1>>CCc1c(CC=O)cccc1-c1nsc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)n1,,C1CCOC1,,Cl,,test
US20130237525A1,O=Cc1cccc(O)c1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>O=Cc1cccc(OCC(F)(F)F)c1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20040235822A1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4cncn4C4CC4)cc2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4cncn4C4CC4)cc2)CCN3CC(C)C)cc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20160159797A1,Brc1cc2cn[nH]c2cn1.OB(O)c1cccnc1>>c1cncc(-c2cc3cn[nH]c3cn2)c1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US05624935,CCOC(=O)Cc1cn2ccccc2n1>>OCCc1cn2ccccc2n1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130225620A1,CNCc1ccc2c(ncn2C2CCCCO2)c1Cl.Fc1cnc(Cl)nc1Nc1cc(C2CC2)[nH]n1>>CN(Cc1ccc2[nH]cnc2c1Cl)c1ncc(F)c(Nc2cc(C3CC3)[nH]n2)n1,,CCCCO,,CCN(C(C)C)C(C)C,Cl,test
US20140024650A1,Clc1cnc(Cl)nc1.OB(O)c1ccc(O)cc1>>Oc1ccc(-c2ncc(Cl)cn2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150099766A1,COC(=O)c1cc(NC(=O)c2c(C(F)(F)F)c(C(F)(F)C(F)(F)F)nn2C)ncc1Cl>>Cn1nc(C(F)(F)C(F)(F)F)c(C(F)(F)F)c1C(=O)Nc1cc(C(=O)O)c(Cl)cn1,,CO,,[Na+].[OH-],,test
US20150284381A1,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.COC(=O)c1ccc2c(c1)CCCC2(O)c1nccs1>>COC(=O)c1ccc2c(c1)CCCC2(O[Si](C)(C)C(C)(C)C)c1nccs1,,ClCCl,,O,,test
US20120101100A1,CC(C)N=C=O.COC(=O)c1cncc(-c2cnc(N)cc2-c2nc(C(F)(F)F)cs2)c1>>COC(=O)c1cncc(-c2cnc(NC(=O)NC(C)C)cc2-c2nc(C(F)(F)F)cs2)c1,,ClC(Cl)Cl,,,,test
US05859051,CCCc1c(OCCCBr)ccc2cc(CC)c(=O)oc12.COC(=O)Cc1ccc(SC(=O)N(C)C)c(Cl)c1>>CCCc1c(OCCCSc2ccc(CC(=O)OC)cc2Cl)ccc2cc(CC)c(=O)oc12,,CO,,C[O-].[Na+],,test
US20030105133A1,Cc1cccc(C#CCCS(C)(=O)=O)c1.OC1(Cc2ccccc2)CCNCC1>>Cc1cccc(C#CCCN2CCC(O)(Cc3ccccc3)CC2)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04518607,CC(C)(C)C(Cn1ccnc1)Oc1ccc([N+](=O)[O-])cc1>>CC(C)(C)C(Cn1ccnc1)Oc1ccc(N)cc1,,CCO,,[NH4+].[OH-],,test
US20050209217A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)C1NCCC1SC(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1CCC(SC(c2ccccc2)(c2ccccc2)c2ccccc2)C1C(=O)O,,ClCCl,,CCN(CC)CC,,test
US20140235612A1,N#Cc1ccc(Nc2ncccc2[N+](=O)[O-])cc1F>>N#Cc1ccc(Nc2ncccc2N)cc1F,[Zn],O,,C1CCOC1,[Cl-].[NH4+],test
US20140140956A1,BrP(Br)Br.COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCO)c(-c4ccc(S(C)(=O)=O)cc4)c3)nc2c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCBr)c(-c4ccc(S(C)(=O)=O)cc4)c3)nc2c1,,CN(C)C=O,,,,test
US04897392,CN1N=CN2C1=Cn1c(cc3ccc(Cl)cc31)-c1ccccc12.O=C1CCC(=O)N1Cl>>CN1N=CN2C1=Cn1c(cc3c(Cl)cc(Cl)cc31)-c1ccccc12,,CN(C)C=O,,O,,test
US20060004195A1,C#CCBr.CC1(C)OC(=O)C(c2cccc(Cl)c2)O1>>C#CCC1(c2cccc(Cl)c2)OC(C)(C)OC1=O,,Cc1ccccc1,,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20150252038A1,COC(=O)c1cc(C2CC2)c(OCC2CCNCC2)cc1F.Cn1nc(C(F)(F)F)c(C=O)c1Cl>>COC(=O)c1cc(C2CC2)c(OCC2CCN(Cc3c(C(F)(F)F)nn(C)c3Cl)CC2)cc1F,,CC(Cl)Cl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090042918A1,COC(=O)c1ccc(Cl)cc1N.O=C(Cl)c1sccc1Cl>>COC(=O)c1ccc(Cl)cc1NC(=O)c1sccc1Cl,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20150175623A1,CC(C)[Si](OCCN1CCN(CC(F)F)CC1)(C(C)C)C(C)C>>OCCN1CCN(CC(F)F)CC1,,C1CCOC1,,,,test
US20050272765A1,CCN.N#Cc1c(Cl)ccc([N+](=O)[O-])c1Cl>>CCNc1c([N+](=O)[O-])ccc(Cl)c1C#N,,C1CCOC1,CCOC(C)=O,,,test
US20160102059A1,COC(=O)c1cc(C(C)(C)C)cc(NC(=O)Oc2ccccc2)c1OC.COc1cc(Nc2cc(Oc3ccc(N)c4ccccc34)ccn2)ccc1C(=O)NCCN1CCS(=O)CC1>>COC(=O)c1cc(C(C)(C)C)cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc(C(=O)NCCN5CCS(=O)CC5)c(OC)c4)c3)c3ccccc23)c1OC,,C1CCOC1,,,,test
US05972975,CSc1c(C)ccnc1NC(=O)C(C)(C)C>>CSc1c(C)ccnc1N,,Cl,O,,,test
US20150111938A1,Brc1cccnc1.O=C(CCSCCC(F)(F)F)Nc1c[nH]nc1Cl>>O=C(CCSCCC(F)(F)F)Nc1cn(-c2cccnc2)nc1Cl,[Cu]I,CC#N,,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US20090029955A1,CC1(C)CCc2c(-c3ccco3)nc3sc4c(Cl)ncnc4c3c2C1.NCCN1CCOCC1>>CC1(C)CCc2c(-c3ccco3)nc3sc4c(NCCN5CCOCC5)ncnc4c3c2C1,,CCO,,,,test
US20050282887A1,NCC1Oc2ccccc2O1.NS(N)(=O)=O>>NS(=O)(=O)NCC1Oc2ccccc2O1,,C1COCCO1,,,,test
US20080090856A1,N#Cc1ccc(Br)cn1.Nc1cc(O)ccc1F>>N#Cc1ccc(Oc2ccc(F)c(N)c2)cn1,,CC(=O)N(C)C,,CC(C)(C)[O-].[K+],,test
US20050245530A1,COc1ccc(CN)cc1.O=[N+]([O-])c1ccc(Oc2ccnc(Cl)n2)c(F)c1>>COc1ccc(CNc2nccc(Oc3ccc([N+](=O)[O-])cc3F)n2)cc1,,ClCCl,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US03959309,CN(C)C1CCc2[nH]c3c(Br)cccc3c2C1.CN(C)C=O.NCCN>>CN(C)C1CCc2[nH]c3c(C#N)cccc3c2C1,,O,,,,test
US20120184544A1,COC(=O)c1cc(O)cc(Oc2ccc(-c3nnc(C)o3)cc2)c1.O=C1NCC[C@H]1O>>COC(=O)c1cc(Oc2ccc(-c3nnc(C)o3)cc2)cc(O[C@H]2CCNC2=O)c1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080280876A1,COC(=O)[C@H]1C[C@@H]1c1ccc(-c2nc(-c3ccc(OC(C)C)c(Cl)c3)no2)cc1>>CC(C)Oc1ccc(-c2noc(-c3ccc([C@@H]4C[C@H]4C(=O)O)cc3)n2)cc1Cl,Cl,CCO,,CC(=O)O,[Na+].[OH-],test
US20160106842A1,CCCCCCCCCC(=O)OCCCCCCCCO.CS(=O)(=O)Cl>>CCCCCCCCCC(=O)OCCCCCCCCOS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20050154011A1,O=C(N1CCc2ccc([N+](=O)[O-])cc2C1)C(F)(F)F>>O=[N+]([O-])c1ccc2c(c1)CNCC2,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20090181942A1,CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2-n2c1nnc2C(F)(F)F>>COc1cccc([C@H]2O[C@H](CC(=O)O)c3nnc(C(F)(F)F)n3-c3ccc(Cl)cc32)c1OC,,C1COCCO1,CCOC(C)=O,Cl,,test
US20080176829A1,COc1cc2c(ccn2S(=O)(=O)c2ccccc2)cc1OCCNC(C)=O>>COc1cc2c(ccn2S(=O)(=O)c2ccccc2)c2c1OCCN=C2C,,CC#N,,O=P(Cl)(Cl)Cl,,test
US20060223797A1,CC(C)(C)C(=O)Nc1nc(Cl)c2c(I)c[nH]c2n1.COc1c(C)cnc(CCl)c1C>>COc1c(C)cnc(Cn2cc(I)c3c(Cl)nc(NC(=O)C(C)(C)C)nc32)c1C,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080182852A1,CCOC(=O)c1ccccc1N.Clc1ncc(Cl)c(Cl)n1>>CCOC(=O)c1ccccc1Nc1nc(Cl)ncc1Cl,,CCO,,CCN(C(C)C)C(C)C,,test
US20110230518A1,CC(C)(C)OC(=O)CCN1CCc2ccc(C(N)=NO)cc2C1.COCc1cc(C(=O)O)ccc1-c1ccccc1C>>COCc1cc(-c2nc(-c3ccc4c(c3)CN(CCC(=O)OC(C)(C)C)CC4)no2)ccc1-c1ccccc1C,,CCOC(C)=O,,,,test
US20110003793A1,CC(C)N1CCc2[nH]c3cc(-n4ccc(OCc5ccc(F)cn5)cc4=O)ccc3c2CC1.Cl>>CC(C)N1CCc2[nH]c3cc(-n4ccc(OCc5ccc(F)cn5)cc4=O)ccc3c2CC1.Cl,,CO,,,,test
US20070088041A1,O=C1CCC(=O)N1I.O=c1[nH]nc(-c2ccncc2)cc1-c1cc2ccccc2[nH]1>>O=c1[nH]nc(-c2ccncc2)cc1-c1[nH]c2ccccc2c1I,,CC(C)=O,,,,test
US20130267499A1,COc1cccc(CBr)c1.C[Si](C)(C)CCOCn1cc2c(n1)NCCCC2=O>>COc1cccc(CN2CCCC(=O)c3cn(COCC[Si](C)(C)C)nc32)c1,,CN1CCCC1=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050245514A1,CCC(O[Si](CC)(CC)CC)C(C)C1OC1CC(C)(/C=C/C=C(\C)C1OC(=O)CC(O[Si](CC)(CC)CC)CCC(C)C(O)C=CC1C)O[Si](CC)(CC)CC.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCC(O[Si](CC)(CC)CC)C(C)C1OC1CC(C)(/C=C/C=C(\C)C1OC(=O)CC(O[Si](CC)(CC)CC)CCC(C)C(C(=O)OOc2ccc([N+](=O)[O-])cc2)C=CC1C)O[Si](CC)(CC)CC,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US06008229,C/C(=C/CO)c1ccc(C)c(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1C.CS(=O)(=O)Cl>>C/C(=C/COS(C)(=O)=O)c1ccc(C)c(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1C,,ClCCl,,CCN(CC)CC,,test
US20110105532A1,CC(C)(C)OC(=O)NC1CCc2cc(/C=C/C(=O)O)ccc21.NC(c1cccc(C(F)(F)F)c1)C(F)(F)F>>CC(C)(C)OC(=O)NC1CCc2cc(/C=C/C(=O)NC(c3cccc(C(F)(F)F)c3)C(F)(F)F)ccc21,,CCOC(C)=O,CN(C)C=O,COc1nc(OC)nc([N+]2(C)CCOCC2)n1.[Cl-],,test
US06410556B1,COC(=O)c1c(CCl)cccc1OC.C[C@@H](c1ccccc1)N1Cc2sc(N)c(C(=O)OC(C)(C)C)c2C[C@H]1CN>>COc1cccc2c1C(=O)N(C[C@@H]1Cc3c(sc(N)c3C(=O)OC(C)(C)C)CN1[C@@H](C)c1ccccc1)C2,,CC#N,,CCN(CC)CC,,test
US03937702,CC1(C)c2cc(O)ccc2OC1N1CCCCC1.CS(=O)(=O)Cl>>CC1(C)c2cc(OS(C)(=O)=O)ccc2OC1N1CCCCC1,,c1ccncc1,,O,,test
US06372770B1,COc1ccc(C=O)cc1OC1CCCC1.Nc1cccc2nc(-c3cccc(Cl)c3)oc12>>COc1ccc(CNc2cccc3nc(-c4cccc(Cl)c4)oc23)cc1OC1CCCC1,,CO,,[BH3-]C#N.[Na+],,test
US20070299051A1,COC(=O)c1cc(C)c2c(c1)S(=O)(=O)Cc1cc(NCCN3CCCC3)cc(Cl)c1O2.COCC(=O)Cl>>COCC(=O)N(CCN1CCCC1)c1cc(Cl)c2c(c1)CS(=O)(=O)c1cc(C(=O)OC)cc(C)c1O2,,O,,CO,,test
US20110212939A1,COC(=O)Cc1ccc(OCCCC2CCN(C(=O)OC(C)(C)C)CC2)cc1>>CC(C)(C)OC(=O)N1CCC(CCCOc2ccc(CC(=O)O)cc2)CC1,,CO,,[Na+].[OH-],,test
US20040132727A1,COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1N.NCCN1CCCCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NCCN1CCCCC1,,ClC(Cl)Cl,O,CCN(CC)CC,,test
US20120149699A1,Cc1c(N(C(=O)OC(C)(C)C)S(=O)(=O)c2ccccc2)nc2ccc(C(F)(F)F)cn12>>Cc1c(NS(=O)(=O)c2ccccc2)nc2ccc(C(F)(F)F)cn12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030008873A1,CCN(CC)c1ccccc1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(N)(=O)=O)cc1,,C1CCOC1,,,,test
US20140155391A1,COc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1NC(=O)CCl.C[C@@H]1CN[C@@H](C)CN1C(=O)OC(C)(C)C>>COc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1NC(=O)CN1C[C@@H](C)N(C(=O)OC(C)(C)C)C[C@@H]1C,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US06521643B1,COc1cccnc1-c1cccc(N=C(NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)c1.Cl.ClCCl>>COc1cccnc1-c1cccc(NC(=N)N)c1.Cl.Cl,,C1COCCO1,ClCCl,,,test
US20100137308A1,COC(=O)c1ccc(OC)cc1N.Cn1cnc(S(=O)(=O)Nc2nc3ccccc3nc2Cl)c1>>COC(=O)c1ccc(OC)cc1Nc1nc2ccccc2nc1NS(=O)(=O)c1cn(C)cn1,,O,,CC(=O)O,,test
US20130143880A1,CC(C)(C)CBr.COc1ccc2[nH]c(=O)n(C)c2c1F>>COc1ccc2c(c1F)n(C)c(=O)n2CC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US09266853B2,CC#CCOc1ccc(C[C@H](NC(=O)[C@@H](/C=C/CCCCCCC(=O)CCCCCCC)[C@@](O)(CCOC(C)=O)C(=O)O)C(=O)OC)cc1>>CC#CCOc1ccc(C[C@H](NC(=O)[C@@H](/C=C/CCCCCCC(=O)CCCCCCC)[C@@](O)(CCO)C(=O)O)C(=O)O)cc1,,CO,,[Li+].[OH-],,test
US20130225619A1,Brc1ncccn1.OCC1CCCCC1>>c1cnc(OCC2CCCCC2)nc1,,C1CCOC1,,[H-].[Na+],,test
US20140275076A1,O=C1Cc2cc(Br)ccc2N1.OB(O)c1ccc(-c2ccccc2)s1>>O=C1Cc2cc(-c3ccc(-c4ccccc4)s3)ccc2N1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20150133457A1,CS(=O)(=O)N1CC[C@H](Nc2ccc([N+](=O)[O-])cc2)C1>>CS(=O)(=O)N1CC[C@H](Nc2ccc(N)cc2)C1,[Fe],C1CCOC1,O,[Cl-].[NH4+],,test
US20040127492A1,COC(=O)c1c2c(nn1CCCNC(=O)OC(C)(C)C)-c1cc(-c3cccc([N+](=O)[O-])c3)c(OC)cc1CC2>>COC(=O)c1c2ccc3cc(OC)c(-c4cccc([N+](=O)[O-])c4)cc3c2nn1CCCNC(=O)OC(C)(C)C,,C1COCCO1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20100022535A1,BrCCCCBr.Cc1cccc(-c2[nH]c(Cc3cccc(N)c3)nc2-c2ccc3ncccc3c2)n1>>Cc1cccc(-c2[nH]c(Cc3cccc(N4CCCC4)c3)nc2-c2ccc3ncccc3c2)n1,,CN(C)C=O,,O,,test
US20120232051A1,Cc1ccccc1-c1ccncc1N(CC(F)(F)F)C(=O)c1cc(C(F)(F)F)nc(C(F)(F)F)c1.OB(O)c1ccccc1F>>Fc1ccccc1-c1ccncc1NCC(F)(F)F,,CCCCCCC,CCOC(C)=O,,,test
US20060148858A1,CC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO.CCOC(=O)Cn1ncc(CC)c1O>>CCc1cnn(CC(=O)O)c1OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1C(C)C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20130296344A1,C=CCOc1c(Br)cc(C=O)cc1OC.N#CCC#N.Oc1ccc2ccccc2c1>>C=CCOc1c(Br)cc(C2C(C#N)=C(N)Oc3cc4ccccc4cc32)cc1OC,,CCO,O,C1CCNCC1,,test
US20020143182A1,CCOC(=O)c1ccc2cc(-c3cc(Br)c4c(c3)OCO4)ccc2c1>>OCc1ccc2cc(-c3cc(Br)c4c(c3)OCO4)ccc2c1,,Cc1ccccc1,,CC(C)C[AlH]CC(C)C,,test
US20090170828A1,COC(=O)c1ccc(N2CC(Oc3ccccc3Br)C2)nn1.NN>>NNC(=O)c1ccc(N2CC(Oc3ccccc3Br)C2)nn1,,CCO,,,,test
US20070082912A1,CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(Br)ccc2O)c1.Fc1ccc(CBr)c(F)c1>>CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2F)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US08703761B2,CC(C)(N)C(=O)Nc1nc(-c2ccccc2)c(Cc2ccccc2)s1.Cc1ccccc1N=C=O>>Cc1ccccc1NC(=O)NC(C)(C)C(=O)Nc1nc(-c2ccccc2)c(Cc2ccccc2)s1,,ClCCl,,,,test
US06248783B1,COC(=O)C(OC1CCCCO1)C(=O)CCC/C=C\C[C@H]1[C@@H](OC2CCCCO2)C[C@@H](OC2CCCCO2)[C@@H]1CO[Si](C)(C)C(C)(C)C>>CC(C)(C)[Si](C)(C)OC[C@H]1[C@H](OC2CCCCO2)C[C@H](OC2CCCCO2)[C@@H]1C/C=C\CCCC(=O)COC1CCCCO1,,C1CCOC1,,[Li+].[OH-],,test
US20100120761A1,NNC(=O)c1ccn2c(-c3cccc(NC(=O)NCC(F)(F)F)c3)cnc2c1.S=C=S>>O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4n[nH]c(=S)o4)ccn23)c1,,CCO,,[K+].[OH-],,test
US20120108582A1,C=CCBr.C[C@H](c1ccccc1)N1C[C@@H](CO[Si](C)(C)C(C)(C)C)CC1=O>>C=CC[C@@H]1C(=O)N([C@H](C)c2ccccc2)C[C@H]1CO[Si](C)(C)C(C)(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04267180,CC(=O)NC(C)(C)C(=O)Nc1ccc(-c2ncc(C(=O)O)c(O)n2)cc1.O=C(n1ccnc1)n1ccnc1>>CC(=O)NC(C)(C)C(=O)Nc1ccc(-c2ncc(C(=O)O)c(O)n2)cc1.c1c[n-]cn1,,C1CCOC1,,,,test
US20100261673A1,COc1ccc(Oc2ccc(-c3noc(-c4ccc(F)cc4)n3)cc2)cc1>>Oc1ccc(Oc2ccc(-c3noc(-c4ccc(F)cc4)n3)cc2)cc1,,ClCCl,,BrB(Br)Br,O,test
US20140023611A1,CN(CCN1CCC[C@H]1C(=O)O)C(=O)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)N[C@H]3CCCc4ccccc43)ccn2)c1.CNCCOCCOCCOCCC(=O)OC(C)(C)C>>CN(CCN1CCC[C@H]1C(=O)N(C)CCOCCOCCOCCC(=O)OC(C)(C)C)C(=O)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)N[C@H]3CCCc4ccccc43)ccn2)c1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080261944A1,CCOC(=O)/C=C/c1ccc(NC(=O)C2(N)CCCC2)cc1.COc1ccc(-c2c(C3CCCCC3)c3ccc(C(=O)O)cc3n2CC(=O)N(C)C)cc1>>COc1ccc(-c2c(C3CCCCC3)c3ccc(C(=O)NC4(C(=O)Nc5ccc(/C=C/C(=O)O)cc5)CCCC4)cc3n2CC(=O)N(C)C)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040082596A1,Nc1nc(-c2nn(Cc3ccccc3F)c3ncccc23)ncc1O.O=C(Cl)N1CCCC1>>Nc1nc(-c2nn(Cc3ccccc3F)c3ncccc23)ncc1OC(=O)N1CCCC1,,C1CCOC1,,[H-].[Na+],,test
US05948785,CCOC(C)=N.CCOC(CN)OCC>>CCOC(CNC(C)=N)OCC,,CCO,,Cl,,test
US06441173B1,CCCBr.COc1ccc2c(-c3cccc(O)c3)cc(=O)oc2c1>>CCCOc1cccc(-c2cc(=O)oc3cc(OC)ccc23)c1,,CC#N,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140315888A1,CC1CN(c2nc3ncc(Cl)cc3nc2NN)CC(C)N1C.COC(OC)OC>>CC1CN(c2nc3ncc(Cl)cc3n3cnnc23)CC(C)N1C,,CCOCC,,,,test
US20150376130A1,CCOC(=O)c1cccnc1NC(C)(C)C>>CC(C)(C)Nc1ncccc1C(=O)O,,O,,C1CCOC1,[Li+].[OH-],test
US20130310393A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cc1ncncc1Br>>Cc1ncncc1B1OC(C)(C)C(C)(C)O1,,CS(C)=O,,CC(=O)[O-].[K+],,test
US20120252815A1,CC(C)(C)OC(=O)N1CCCC(=O)CC1.NCCCCO>>CC(C)(C)OC(=O)N1CCCC(NCCCCO)CC1,,CCO,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20080146616A1,CC(C)I.O=c1ccc(Br)c[nH]1>>CC(C)Oc1ccc(Br)cn1,,CCOC(C)=O,,Cc1ccccc1,,test
US20090181963A1,Nc1ccc(-c2nc(N3CCOCC3)c3nnn(CC(F)(F)F)c3n2)cc1.Nc1ccncc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=C(Nc1ccncc1)Nc1ccc(-c2nc(N3CCOCC3)c3nnn(CC(F)(F)F)c3n2)cc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20060155121A1,CCOC(=O)Nc1c(C)cc(NCc2ccc(C(F)(F)F)cc2)cc1[N+](=O)[O-]>>CCOC(=O)Nc1c(C)cc(NCc2ccc(C(F)(F)F)cc2)cc1N,,C1CCOC1,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US03931239,CC(C)CC(=O)Cl.Cc1ccc2c(c1C)OC(C(=O)O)C2>>Cc1c(C(=O)CC(C)C)cc2c(c1C)OC(C(=O)O)C2,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US06348485B1,CCOC(=O)/C=C/c1ccc2c(c1)CCO2>>CCOC(=O)CCc1ccc2c(c1)CCO2,[Pd],CC(=O)O,,,,test
US04616014,CC(=O)CC(C)=O.Cc1nc(NN)nnc1-c1ccc(Cl)cc1>>Cc1cc(C)n(-c2nnc(-c3ccc(Cl)cc3)c(C)n2)n1,CC(=O)O,CO,,,,test
US06008229,CNc1cccc(OCc2ccccc2)c1[N+](=O)[O-]>>CNc1cccc(OCc2ccccc2)c1N,,CO,,NN,O,test
US20140336252A1,NC1=C([N+](=O)[O-])CC(=NCc2ccc(F)cc2)C=C1>>NC1=C(N)CC(=NCc2ccc(F)cc2)C=C1,[Pd],C1CCOC1,,N#N,,test
US06002008,N#Cc1cnc2ccc([N+](=O)[O-])cc2c1Nc1ccc(F)c(Cl)c1>>N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1,,CCO,,,,test
US20040106616A1,COc1ccc(-c2ncccc2C(F)(F)F)cn1>>O=c1ccc(-c2ncccc2C(F)(F)F)c[nH]1,,Br,CC(=O)O,,,test
US07230007B2,Cl.N=C(N)N.O=C(O)c1cn(-c2ccccn2)c2ncccc12>>Cl.N=C(N)NC(=O)c1cn(-c2ccccn2)c2ncccc12,,C1CCOC1,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20110245205A1,Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C3(O)CCNCC3)s2)c1.O=S(=O)(Cl)c1ccccc1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C3(O)CCN(S(=O)(=O)c4ccccc4)CC3)s2)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110034521A1,Nc1cc(-c2ccc(Cl)cc2)n[nH]1.O=C(O)CS>>O=C(CS)Nc1cc(-c2ccc(Cl)cc2)n[nH]1,,Cc1ccccc1,,[Al],,test
US20080064699A1,CS(=O)(=O)c1ccc2nc(N)sc2c1.O=C(Cl)C12CC3CC(CC(C3)C1)C2>>CS(=O)(=O)c1ccc2nc(NC(=O)C34CC5CC(CC(C5)C3)C4)sc2c1,,CCN(CC)CC,,,,test
US20100261755A1,CC1(C)OB(c2ccc(OC(F)(F)F)cc2F)OC1(C)C.COC(=O)c1ccnc(Cl)c1>>COC(=O)c1ccnc(-c2ccc(OC(F)(F)F)cc2F)c1,Cl[Pd]Cl,CO,,O=C([O-])[O-].[K+].[K+],,test
US20150282482A1,COC(=O)CS.N#Cc1cc(C(F)(F)F)ccc1Cl>>COC(=O)c1sc2ccc(C(F)(F)F)cc2c1N,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20050133762A1,O=C(O)Cc1cccc(F)c1F.O=S(Cl)Cl>>O=C(Cl)Cc1cccc(F)c1F,,ClCCl,,O,,test
US20110269712A1,CN[C@@H]1CCCc2ccccc21.Cc1cc(C(F)(F)F)nn1CC(=O)N1CCC(n2ccc(C(=O)O)n2)CC1>>Cc1cc(C(F)(F)F)nn1CC(=O)N1CCC(n2ccc(C(=O)N(C)[C@@H]3CCCc4ccccc43)n2)CC1,,ClCCl,O,CN1CCOCC1,,test
US20140187588A1,C=C[C@H](OCc1ccccc1)[C@@H](OCc1ccccc1)[C@H](C)O.CC(=O)OC(C)=O>>C=C[C@H](OCc1ccccc1)[C@@H](OCc1ccccc1)[C@H](C)OC(C)=O,CN(C)c1ccncc1,ClCCl,,,,test
US20160122342A1,CCN(c1cccc2c1CC=CCCc1cc(C)nc(OC)c1CN(CCO[Si](C)(C)C(C)(C)C)C2=O)C1CCOCC1>>CCN(c1cccc2c1CC=CCCc1cc(C)[nH]c(=O)c1CN(CCO)C2=O)C1CCOCC1,,C1COCCO1,CO,Cl,,test
US20160152543A1,CCOC(=O)C(=O)c1c(OCc2ccccc2)c(Cl)cc2ncccc12>>CCOC(=O)C(O)c1c(OCc2ccccc2)c(Cl)cc2ncccc12,,CCO,,[BH4-].[Na+],,test
US20150094328A1,O=C(OCc1ccc(F)cc1)c1cn(Cc2ccc(F)cc2)c2cccnc12>>O=C(O)c1cn(Cc2ccc(F)cc2)c2cccnc12,,C1CCOC1,O,[Li+].[OH-],,test
US05258396,CCOC(=O)c1sc(NC)nc1C(C)c1ccc(-c2ccc(F)cc2)c(F)c1>>CNc1nc(C(C)c2ccc(-c3ccc(F)cc3)c(F)c2)c(C(=O)O)s1,,CO,O,[K+].[OH-],,test
US20040097589A1,COc1cc(Br)c(Oc2ccc([N+](=O)[O-])cc2)c(Br)c1>>O=[N+]([O-])c1ccc(Oc2c(Br)cc(O)cc2Br)cc1,,ClCCl,,Cl,,test
US20110003866A1,Cc1ccc(F)cc1CNc1ccc([N+](=O)[O-])c(N(C)C)n1>>Cc1ccc(F)cc1CNc1ccc(N)c(N(C)C)n1,[Ni],C1CCOC1,,NN,O,test
US20160272602A1,N[C@@H]1CCN(c2cc(Cl)ccc2C=O)C1.O=C(Cl)CCCCl>>O=Cc1ccc(Cl)cc1N1CC[C@@H](NC(=O)CCCCl)C1,,O,,CCN(CC)CC,ClCCl,test
US20160137618A1,CC(C)(C)OC(=O)Nc1ccc(C[C@](C)(N=C=O)C(=O)OC(C)(C)C)cn1.CC(C)[C@H]1COCCCCOc2ccc(cc2)C[C@@H](N)C(=O)N1>>CC(C)[C@H]1COCCCCOc2ccc(cc2)C[C@@H](NC(=O)N[C@@](C)(Cc2ccc(NC(=O)OC(C)(C)C)nc2)C(=O)OC(C)(C)C)C(=O)N1,,O=P([O-])([O-])[O-],,,,test
US20150057271A1,COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(c2)OCCN3C(=O)Oc2ccc([N+](=O)[O-])cc2)cc1>>O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCOc2cc(S(=O)(=O)Nc3nccs3)ccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US05294612,Cc1nn(C2CCC2)c2nc(-c3ccncc3)nc(N)c12.O=N[O-]>>Cc1[nH]n(C2CCC2)c2nc(-c3ccncc3)nc(=O)c1-2,,O,O=S(=O)(O)O,O=C([O-])[O-].[K+].[K+],,test
US20100069629A1,C1COCCN1.Cc1ccc(C(=O)O)cc1Br>>Cc1ccc(C(=O)N2CCOCC2)cc1Br,,ClCCl,,[Cl-].[NH4+],,test
US20100273806A1,CCOC(=O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cnc(F)c(C)c4)n3)cc21.CC[C@H](C)O>>CCC(C)Oc1ncc(-c2nc(-c3ccc4[nH]c5c(c4c3)CCC5CC(=O)O)no2)cc1C,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US04423071,CCCC(CCC)C(=O)O.ClCC1CO1>>CCCC(CCC)C(=O)OCC1CO1,,CN(C)C=O,,Cc1ccccc1,[Na+].[OH-],test
US20160027592A1,CCO.C[Si](C)(C)Cl.O=S(=O)(O)Cl>>CCOS(=O)(=O)O[Si](C)(C)C,,ClCCl,,,,test
US05230710,CC(=O)O.Cc1c(NC(=O)NOCCCl)cccc1NC(=O)NOCCCl>>Cc1c(NCCO)cccc1NCCO,,O,,CO,[K+].[OH-],test
US20100305133A1,COC(=O)c1c(OC)ccc2nc(Cl)c(-c3ccccc3)nc12.NCc1ccccc1>>COC(=O)c1c(OC)ccc2nc(NCc3ccccc3)c(-c3ccccc3)nc12,,C1CCOC1,CO,CCN(CC)CC,,test
US20100324074A1,NCc1ccc2ncccc2c1.O=[N+]([O-])c1cnc(Cl)nc1Cl>>O=[N+]([O-])c1cnc(Cl)nc1NCc1ccc2ncccc2c1,,C1COCCO1,,CCN(C(C)C)C(C)C,ClCCl,test
US20030055265A1,CO[C@H](C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1)[C@H](O)c1ccc(OCCc2nc(-c3ccccc3)oc2C)c2ccsc12>>CO[C@@H](Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)c2ccsc12)C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20160009744A1,Cc1sc(C2OCCO2)cc1[C@H](O)c1cc(Cl)ccc1CCO[Si](C)(C)C(C)(C)C>>Cc1sc(C2OCCO2)cc1[C@H](O)c1cc(Cl)ccc1CCO,,C1CCOC1,,,,test
US04898874,Cc1cccc2c(-c3ccc(Cl)cc3Cl)onc12.O=C1CCC(=O)N1Br>>Clc1ccc(-c2onc3c(CBr)cccc23)c(Cl)c1,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US05538965,O=C1Cc2cc([N+](=O)[O-])ccc2Sc2ccccc21.c1cc2c(cc1CN1CCNCC1)OCO2>>O=[N+]([O-])c1ccc2c(c1)C=C(N1CCN(Cc3ccc4c(c3)OCO4)CC1)c1ccccc1S2,Cl[Ti](Cl)(Cl)Cl,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US20070244158A1,CC(=O)Cl.Cc1cc(F)ccc1[C@H]1CN(C2CNC2)CC[C@@H]1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(=O)N1CC(N2CC[C@H](N(C)C(=O)C(C)(C)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H](c3ccc(F)cc3C)C2)C1,,ClC(Cl)Cl,O,CCN(CC)CC,ClCCl,test
US20100075990A1,NCCN1CCOCC1.O=C(O)c1csc(-c2cnc(-c3ccccc3)nc2)n1>>O=C(NCCN1CCOCC1)c1csc(-c2cnc(-c3ccccc3)nc2)n1,CN(C)C=O,O=S(Cl)Cl,,CCN(C(C)C)C(C)C,,test
US20160009683A1,CCOC(=O)C(F)(F)c1cccc(OCCN2CCC(F)(F)CC2)c1>>O=C(O)C(F)(F)c1cccc(OCCN2CCC(F)(F)CC2)c1,,C1CCOC1,O,CO,[Li+].[OH-],test
US05412124,C=C(C)C(=C)C.O=C1C=CC(=O)C=C1>>CC1=C(C)CC2=C(C1)C(=O)C=CC2=O,,CC(=O)O,Cc1ccccc1,O,,test
US20080108663A1,CCS(=O)(=O)N1CCC(CN)(CC2CC2)CC1.O=C(Cl)c1ccc(Cl)cc1Cl>>CCS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(CC2CC2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080287479A1,C=[N+]=[N-].CC1CCC(C(=O)Cl)CC1.Cl>>CC1CCC(C(=O)CCl)CC1,,CCOCC,,,,test
US20060148858A1,CCOC(=O)CP(=O)(OCC)OCC.Cn1nc(OCc2ccccc2)cc1C=O>>CCOC(=O)/C=C/c1cc(OCc2ccccc2)nn1C,,O,,CN(C)C=O,[H-].[Na+],test
US20130053384A1,CCCS(=O)(=O)N(c1cc(F)c(F)c(C(=O)c2ccc3ncc(N4CCOCC4)nc3c2)c1F)S(=O)(=O)CCC>>CCCS(=O)(=O)Nc1cc(F)c(F)c(C(=O)c2ccc3ncc(N4CCOCC4)nc3c2)c1F,,CO,,[Na+].[OH-],,test
US05556864,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccccc1CCc1ccccc1.Cl>>Cl.c1ccc(CCc2ccccc2OC[C@H]2CCCN2)cc1,,C1COCCO1,,,,test
US20150080549A1,C=CCCC(=O)Cl.N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O>>C=CCCC(=O)N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O,,C1CCOC1,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20010034343A1,CCOC(=O)c1ccc(Cn2c(N3CCCNCC3)nc3ccccc32)o1>>OCc1ccc(Cn2c(N3CCCNCC3)nc3ccccc32)o1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110269780A1,C=C(CCC)C(=O)OCC.Nc1ncccc1[N+](=O)[O-]>>CCCC(CNc1ncccc1[N+](=O)[O-])C(=O)OCC,,CCOC(C)=O,CN(C)C=O,C1CCC2=NCCCN2CC1,O,test
US20100331335A1,CCOC(=O)Cn1c(=O)ccc2cc(Br)ccc21.CN(C)C=O>>CCOC(=O)Cn1c(=O)ccc2cc(C#N)ccc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,CCOC(C)=O,,test
US05116844,CC(c1cccnc1)C(O)(Cn1cncn1)c1ccc(F)cc1F.O=C(OO)c1cccc(Cl)c1>>CC(c1ccc[n+]([O-])c1)C(O)(Cn1cncn1)c1ccc(F)cc1F,,ClCCl,,,,test
US20090054508A1,O=Cc1ccn(-c2ccccc2/C=C/c2n[nH]c3ccccc23)c1>>OCc1ccn(-c2ccccc2/C=C/c2n[nH]c3ccccc23)c1,,CO,,O,[BH4-].[Na+],test
US20140323468A1,CC(=O)Cl.FC(F)(F)c1cncc(-c2cnc3c(c2)CCCN3)c1>>CC(=O)N1CCCc2cc(-c3cncc(C(F)(F)F)c3)cnc21,,ClCCl,,CCN(CC)CC,,test
US20080076762A1,CCCCCc1ccc(C(=O)N(Cc2ccc([N+](=O)[O-])cc2)C2CCN(CCC(C)C)CC2)cc1>>CCCCCc1ccc(C(=O)N(Cc2ccc(N)cc2)C2CCN(CCC(C)C)CC2)cc1,[Pd],CCOC(C)=O,,,,test
US20090054475A1,CC(C)(C)OC(=O)N1CCC(c2noc(CO)n2)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCC(c2noc(COS(C)(=O)=O)n2)CC1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20130197237A1,NCCN1CCNC1=O.O=Cc1ccc(C(=O)Cl)cc1>>O=Cc1ccc(C(=O)NCCN2CCNC2=O)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20160024091A1,CC(C=O)c1ccc(-n2cnnn2)nn1.CC1=C(N2CCC3(CCNCC3)C2=O)COC1=O>>CC1=C(N2CCC3(CCN(CC(C)c4ccc(-n5cnnn5)nn4)CC3)C2=O)COC1=O,CC(=O)O,ClC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20160096827A1,COc1cc(N)ccc1N1CCN(C)CC1.N#Cc1cc(-c2ncnc(Cl)n2)ccc1OC1CCOCC1>>COc1cc(Nc2ncnc(-c3ccc(OC4CCOCC4)c(C#N)c3)n2)ccc1N1CCN(C)CC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20010011086A1,CC(C)(C)[Si](C)(C)Cl.O=C1c2cc(CO)ccc2-c2c(O)cccc21>>CC(C)(C)[Si](C)(C)OCc1ccc2c(c1)C(=O)c1cccc(O)c1-2,,CN(C)C=O,,c1c[nH]cn1,,test
US20040192681A1,Brc1ccc2cc[nH]c2c1.O=C(O)c1ccc(B(O)O)cc1>>O=C(O)c1ccc(-c2ccc3cc[nH]c3c2)cc1,,CCO,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],,test
US07176324B1,CC1C(C)(C)C2CCCC(O)C2C1(C)C.CCOCOCC>>CCOCOC1CCCC2C1C(C)(C)C(C)C2(C)C,,Cc1ccccc1,,,,test
US20070208007A1,CCCN(CCC)CCCCN(Cc1ccc(CNCc2ncc[nH]2)cc1)S(C)(=O)=O.O=C1CCCc2cccnc21>>CCCN(CCC)CCCCN(Cc1ccc(CN(Cc2ncc[nH]2)C2CCCc3cccnc32)cc1)S(C)(=O)=O,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20140243302A1,COc1ccc2ncc(F)c(CC(O)(C(F)(F)F)C34CCC(NC(=O)OC(C)(C)C)(CC3)CO4)c2n1>>COc1ccc2ncc(F)c(CC(O)(C(F)(F)F)C34CCC(N)(CC3)CO4)c2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05064833,CCN.Cc1ccccc1NCc1nc(Cl)nc2ccccc12>>CCNc1nc(Nc2ccccc2C)c2ccccc2n1,,CCO,,,,test
US20150158847A1,CCOc1cc(C=NO)ccc1OCc1ccc(OC)nc1>>CCOc1cc(CN)ccc1OCc1ccc(OC)nc1,[Zn],CC(=O)O,CCOC(C)=O,,,test
US20160200725A1,CC(C)(C)OC(=O)NC1CCN(CCO)CC1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NC1CCN(CCOS(C)(=O)=O)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20140315886A1,CN(C(=O)OC(C)(C)C)c1nc(-c2ccc[n+]([O-])c2)nc2cc(-c3cc(F)ccc3F)ccc12>>CNc1nc(-c2ccc[n+]([O-])c2)nc2cc(-c3cc(F)ccc3F)ccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100305133A1,CCOC(=O)CNC(=O)c1c(O)cc(-c2ccccc2)c2nccnc12>>O=C(O)CNC(=O)c1c(O)cc(-c2ccccc2)c2nccnc12,,C1CCOC1,CO,[Na+].[OH-],,test
US20030166639A1,Cc1cc(-c2cccc(C(=O)CC(=O)Nc3cc(C(F)(F)F)c(Cl)cc3NC(=O)OC(C)(C)C)c2)c(C)cn1>>Cc1cc(-c2cccc(C3=Nc4cc(Cl)c(C(F)(F)F)cc4NC(=O)C3)c2)c(C)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120028924A1,C=CP(=O)(C=C)c1ccc([N+](=O)[O-])c(OC)c1.CCOC(=O)CC(=O)OCC>>CCOC(=O)C1(C(=O)OCC)CCP(=O)(c2ccc([N+](=O)[O-])c(OC)c2)CC1,,CS(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20070219194A1,Cc1ccc(CC(=O)OC(C)(C)C)c(C(=O)OC(C)(C)C)c1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)Cc1ccc(CBr)cc1C(=O)OC(C)(C)C,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20050209225A1,COC(=O)C(C)Cc1cc2cc(OCc3ccccc3)ccc2[nH]1>>COC(=O)C(C)Cc1cc2cc(O)ccc2[nH]1,[Pd],CCO,,,,test
US04352792,CC(=O)OC[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.COc1cc(O)c2c(=O)c(OC)c(-c3ccc(O)c(OC)c3)oc2c1>>COc1cc(O)c2c(=O)c(OC)c(-c3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(OC)c3)oc2c1,,CC(C)=O,,[Na+].[OH-],,test
US20140155597A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.COC(=O)c1cc(C)ccc1Br>>COC(=O)c1cc(C)ccc1C(C)=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,,,test
US20090042931A1,CC(C)Cc1cc(-c2cccc(CBr)c2)c(S(=O)(=O)NC(C)(C)C)s1.c1cn[nH]c1>>CC(C)Cc1cc(-c2cccc(Cn3cccn3)c2)c(S(=O)(=O)NC(C)(C)C)s1,,C1COCCO1,,,,test
US20150152108A1,COC(=O)c1cc(-c2ccc3c(n2)N(C(=O)Nc2cnccn2)[C@H]2CCN3C2)ccn1>>O=C(Nc1cnccn1)N1c2nc(-c3ccnc(CO)c3)ccc2N2CC[C@H]1C2,,C1CCOC1,,[BH4-].[Na+],,test
US20130102776A1,COC(=O)c1c(OC)ccc2c1OCC2=O.O=Cc1n[nH]c2ccccc12>>COC(=O)c1c(OC)ccc2c1O/C(=C\c1n[nH]c3ccccc13)C2=O,C1CCNCC1,CO,,,,test
US05714498,Cc1ccc(C=Cc2ccncc2)o1.ClCc1nc2ccccc2[nH]1>>Cc1ccc(/C=C/C2=CCN(Cc3nc4ccccc4[nH]3)CC2)o1,,CN(C)C=O,,,,test
US20150210697A1,COc1ccc(CN(c2nc(Nc3cc(C#N)cc(C(C)CCO)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1>>CC(CCO)c1cc(C#N)cc(Nc2nc(NC3CC3)c3ncc(C#N)n3n2)c1Cl,,ClCCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US20120232052A1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.FC(F)(F)Oc1cccc(S)c1>>CC(C)(C)OC(=O)N1CCC(Sc2cccc(OC(F)(F)F)c2)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130225580A1,CC(C)Oc1ccc(S(=O)(=O)Cl)cc1.Nc1cc(C(F)(F)F)nn1-c1cccc2ncccc12>>CC(C)Oc1ccc(S(=O)(=O)Nc2cc(C(F)(F)F)nn2-c2cccc3ncccc23)cc1,,c1ccncc1,,,,test
US20140018319A1,CC(C)(C)OP(=O)(OCCCC(=O)O)OC(C)(C)C.CCN(Cc1ccc(OC)cc1)c1nc(Nc2cc(C#N)cc(N3CC[C@@H](NC(=O)OC)[C@H](O)C3)c2Cl)nn2c(C#N)cnc12>>CCN(Cc1ccc(OC)cc1)c1nc(Nc2cc(C#N)cc(N3CC[C@@H](NC(=O)OC)[C@H](OC(=O)CCCOP(=O)(OC(C)(C)C)OC(C)(C)C)C3)c2Cl)nn2c(C#N)cnc12,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20080267887A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CCc1cccc(CC)c1-c1cc2cc[nH]c2cn1>>CCc1cccc(CC)c1-c1cc2c(C3=CCN(C(=O)OC(C)(C)C)CC3)c[nH]c2cn1,,CO,,O=C([O-])[O-].[Cs+].[Cs+],,test
US07015237B2,CN(C)C=O.COC(=O)c1cnc(O)c(C(=O)O)c1.NCc1ccccc1.On1nnc2ccccc21>>O=C(O)c1c[nH]c(=O)c(C(=O)N(Cc2ccccc2)Cc2ccccc2)c1,,CN(C)C=O,O,CCN=C=NCCCN(C)C,Cl,test
US20100261687A1,CCOC(=O)c1cc(-c2nnnn2C)cc([N+](=O)[O-])c1>>CCOC(=O)c1cc(N)cc(-c2nnnn2C)c1,[Pd],CCO,CCOC(C)=O,,,test
US20070066618A1,CCOC(=O)Cc1ccc(-n2c(CC)nc3cc(Cl)c(Cl)cc32)cc1>>CCc1nc2cc(Cl)c(Cl)cc2n1-c1ccc(CC(=O)O)cc1,,CO,,[Na+].[OH-],,test
US20120142671A1,N#Cc1cc(F)c(F)cc1Br.NC(=O)[C@H](N)Cc1ccccc1>>N#Cc1cc(F)c(N[C@H](Cc2ccccc2)C(N)=O)cc1Br,,CCOC(C)=O,CS(C)=O,CCN(C(C)C)C(C)C,O,test
US20040039038A1,CCCCCCC(=O)N(C)Cc1cccc(-c2ccc(C=C3SC(=O)NC3=O)cc2)c1>>CCCCCCC(=O)N(C)Cc1cccc(-c2ccc(CC3SC(=O)NC3=O)cc2)c1,,C1COCCO1,,,,test
US20080182802A1,C=CC[C@@]1(c2cc(Cc3ccc(CC)cc3)c(Cl)cc2O)O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1.O=C(OO)c1cccc(Cl)c1>>CCc1ccc(Cc2cc3c(cc2Cl)OC(CO)C[C@]32O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1,,ClCCl,,,,test
US20060270706A1,CCOC(=O)CCCn1ncc(/C=C2\CN(C(C(=O)C3CC3)c3ccccc3F)CCC2SC(C)=O)n1.Cl>>CCOC(=O)CCCn1ncc(/C=C2\CN(C(C(=O)C3CC3)c3ccccc3F)CCC2S)n1.Cl,,CCO,,O=C([O-])O.[Na+],,test
US05491126,Cc1cc(Br)c2nc(Cl)n[n+]([O-])c2c1.OCC(F)(F)F>>Cc1cc(Br)c2nc(OCC(F)(F)F)n[n+]([O-])c2c1,,C1CCOC1,O,CCOC(C)=O,[H-].[Na+],test
US20110130445A1,COC(=O)CC1(c2ccc(Cl)c(NC(=O)C(c3ccc(Cl)cc3)[C@@H](C)C(F)(F)F)c2)CCC1>>C[C@H](C(C(=O)Nc1cc(C2(CC(=O)O)CCC2)ccc1Cl)c1ccc(Cl)cc1)C(F)(F)F,,C1COCCO1,,Cl,[Na+].[OH-],test
US20110139654A1,CCc1c(C(=O)OC)ccc(OC)c1C>>CCc1c(C(=O)OC)ccc(O)c1C,,ClCCl,,BrB(Br)Br,,test
US20160130222A1,NC1=C(Cl)C(=O)c2ccccc2C1=O.O=C(Cl)c1ccccc1>>O=C(NC1=C(Cl)C(=O)c2ccccc2C1=O)c1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US05629295,CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@@H]3[C@@H]2C(=O)[C@@H](OC(C)=O)[C@@]2(C)[C@H]3C[C@@H]3O[C@]4(CC[C@@H](C)CO4)[C@@H](C)[C@@H]32)C1>>C[C@@H]1CC[C@@]2(OC1)O[C@H]1C[C@H]3[C@@H]4CC[C@H]5C[C@@H](O)CC[C@]5(C)[C@H]4[C@@H](O)[C@@H](O)[C@]3(C)[C@H]1[C@@H]2C,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130190540A1,CC(N=[N+]=[N-])c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(N)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,[Pd],CO,,[H][H],,test
US20040266793A1,CC(C)(N)CN.N#CBr>>Br.CC1(C)CN=C(N)N1,,O,,,,test
US20090233901A1,CI.OCCC1CN(C(c2ccccc2)c2ccccc2)C1>>COCCC1CN(C(c2ccccc2)c2ccccc2)C1,,CN(C)C=O,,[H-].[Na+],,test
US20060100229A1,CCCCn1nc(C(=O)O)cc1CCS(=O)(=O)CCC.CN(C)C=O>>CCCCn1nc(C(N)=O)cc1CCS(=O)(=O)CCC,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20110034416A1,Nc1ccc(Oc2ccnc(N=C(c3ccccc3)c3ccccc3)c2Cl)c(F)c1.O=C(O)c1c[nH]cc(-c2ccc(F)cc2)c1=O>>O=C(Nc1ccc(Oc2ccnc(N=C(c3ccccc3)c3ccccc3)c2Cl)c(F)c1)c1c[nH]cc(-c2ccc(F)cc2)c1=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04309354,CCOC(=O)Oc1cc2occ(C=O)c(=O)c2cc1OC(=O)OCC.NS(=O)(=O)O>>CCOC(=O)Oc1cc2occ(C(=O)O)c(=O)c2cc1OC(=O)OCC,,ClCCl,O,[Na+].[O-]Cl,,test
US06281354B1,COC(=O)C1CCCN(COS(C)(=O)=O)c2c1cc(OCc1ccccc1)c1ccccc21>>COC(=O)C1CCCN(COS(C)(=O)=O)c2c1cc(O)c1ccccc21,[Pd],,,,,test
US20100197651A1,COc1cn(-c2cccc(Br)c2F)nc(C(=O)N(C)OC)c1=O.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>COc1cn(-c2cccc(-c3cnn(C)c3)c2F)nc(C(=O)N(C)OC)c1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20080146611A1,Cc1cccc2c1NCCC2.O=C(O)CSc1ncccc1Cl>>Cc1cccc2c1N(C(=O)CSc1ncccc1Cl)CCC2,CN(C)c1ccncc1,C1CCOC1,ClCCl,CCN=C=NCCCN(C)C,,test
US20070135416A1,C[C@H]1CNC(=O)c2cc3cc(OCc4ccccc4)ccc3n21>>C[C@H]1CNC(=O)c2cc3cc(O)ccc3n21,[Pd],CO,,,,test
US20110130409A1,COc1ncc(CCl)cc1C(F)(F)F.O=P(Cl)(Cl)Cl>>FC(F)(F)c1cc(CCl)cnc1Cl,,CN(C)C=O,,,,test
US20110124642A1,Nn1nc(C(F)(F)F)c2ccccc2c1=O.O=C(O)Cc1ccccc1>>O=C(Cc1ccccc1)Nn1nc(C(F)(F)F)c2ccccc2c1=O,,CC(=O)N(C)C,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070043048A1,CC(C)(N)C#Cc1ccc(-c2ccnc(NC3CC(C)(C)NC(C)(C)C3)n2)s1>>CC(C)(N)CCc1ccc(-c2ccnc(NC3CC(C)(C)NC(C)(C)C3)n2)s1,[Pd],CO,,,,test
US04607041,CCOC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(C)=O.CCOC(=O)CC(=O)c1ccc([N+](=O)[O-])cc1.N>>CCOC(=O)C1=C(C)NC(O)(c2ccc([N+](=O)[O-])cc2)C(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1,,CCO,,,,test
US20140018344A1,CSc1nc(Cl)c(C#N)c(Cl)n1.C[C@H](N)c1nc2ccn(C)c2cc1-c1ccnn1C>>CSc1nc(Cl)c(C#N)c(N[C@@H](C)c2nc3ccn(C)c3cc2-c2ccnn2C)n1,,C1CCOC1,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20100324074A1,c1cnc2ccc(Cn3nnc4cnc(-c5cnn(CCOC6CCCCO6)c5)nc43)cc2c1>>OCCn1cc(-c2ncc3nnn(Cc4ccc5ncccc5c4)c3n2)cn1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05948775,COc1ccc(N2C(=O)c3cccc(OC)c3NC2c2ccc(OCCCl)cc2)cc1>>COc1ccc(-n2c(-c3ccc(OCCCl)cc3)nc3c(OC)cccc3c2=O)cc1,,Cc1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US05990101,NS(=O)(=O)Cl.OCCNCc1csc2cncn12>>NS(=O)(=O)N(CCO)Cc1csc2cncn12,,CN(C)C=O,,CCN(CC)CC,,test
US20100113510A1,BrCCCOc1ccccc1.CC1(C)CN(C(C)(C(=O)O[C@H]2CN3CCC2CC3)c2ccccc2)C1>>CC1(C)CN(C(C)(C(=O)O[C@H]2C[N+]3(CCCOc4ccccc4)CCC2CC3)c2ccccc2)C1.[Br-],,CC#N,,CCOCC,,test
US20080234335A1,FC(F)(F)c1ccc(OCc2ccccc2)c(I)c1.O=C1CCCCC1>>OC1(c2cc(C(F)(F)F)ccc2OCc2ccccc2)CCCCC1,,CCOCC,,[Mg],,test
US20070244159A1,CC(=O)OC(C)=O.CC(C)(CN)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc2[nH]1>>CC(=O)NCC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc2[nH]1,,ClCCl,,O,c1ccncc1,test
US20050171101A1,Nc1cccc(NC(=O)C2CCCCC23OCCO3)c1.O=C1OC(=O)c2ccccc21>>O=C(Nc1cccc(N2C(=O)c3ccccc3C2=O)c1)C1CCCCC12OCCO2,,ClC(Cl)Cl,,,,test
US04499094,CCNCC.O=C(O)c1cc2ccccc2c(-c2cccc(Cl)c2)n1>>CCN(CC)C(=O)c1cc2ccccc2c(-c2cccc(Cl)c2)n1,,ClC(Cl)Cl,,CCN(CC)CC,CCOC(=O)Cl,test
US20160039841A1,COC(=O)CCn1c(=O)c2c(CBr)c(-c3ccc(Cl)cc3)sc2n(C)c1=O.OB(O)c1ccc(Cl)cc1>>COC(=O)CCn1c(=O)c2c(Cc3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)sc2n(C)c1=O,,Cc1ccccc1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120083502A1,Cc1cccc2nc(CO)c(-c3cccc(F)c3)c(=O)n12.O=C1NC(=O)c2ccccc21>>Cc1cccc2nc(CN3C(=O)c4ccccc4C3=O)c(-c3cccc(F)c3)c(=O)n12,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050014812A1,CCOC(=O)c1cc(C)c(NC(C)=O)c(N)c1>>CCOC(=O)c1cc(C)c2nc(C)[nH]c2c1,,CCO,,O=S(=O)(O)O,,test
US20100273806A1,CCOC(=O)CC1(C(=O)OCC)CCCC1=O>>O=C(O)CC1CCCC1=O,,CC(=O)O,Cl,,,test
US20150175604A1,Cc1nnc2ccc3c(cc(-c4ccn[nH]4)n3Cc3ccccc3)n12.ClCCN1CCOCC1>>Cc1nnc2ccc3c(cc(-c4ccn(CCN5CCOCC5)n4)n3Cc3ccccc3)n12,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20030139418A1,CCN(Cc1ccccc1Oc1ccccc1)c1ccc(C(=O)OC)cn1>>CCN(Cc1ccccc1Oc1ccccc1)c1ccc(C(=O)O)cn1,,C1CCOC1,CO,[Na+].[OH-],,test
US06492355B1,Cc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1[N+](=O)[O-]>>Cc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ccc1N,[Fe],O,,CCO,[Cl-].[NH4+],test
US20070106074A1,CCOC(=O)c1ccc(Sc2ccccc2C(=O)OC)c([N+](=O)[O-])c1>>Nc1cc(C(=O)O)ccc1Sc1ccccc1C(=O)O,,C1CCOC1,,[Li+].[OH-],,test
US20090042890A1,CCOC(=O)c1nc(N[C@@H]2CCN(C(=O)OC(C)(C)C)C2)nc2c1[nH]c(=O)n2-c1ccccc1OC.CCOC(=O)c1nc(N[C@@H]2CCNC2)nc2c1[nH]c(=O)n2-c1ccccc1OC>>COc1ccccc1-n1c(=O)[nH]c2c(C(N)=O)nc(N[C@@H]3CCNC3)nc21,,ClCCl,O=C(O)C(F)(F)F,,,test
US05236957,NCC(N)=O.O=Cc1cccc(Cl)c1OCc1ccccc1>>NC(=O)CNCc1ccc(OCc2cccc(Cl)c2)cc1,,CO,,Cl,[BH3-]C#N.[Na+],test
US20130172302A1,O=C(CCl)c1ccccc1.O=C(O[C@H]1CN2CCC1CC2)C(c1ccccc1)N1CCCC1=O>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C(c1ccccc1)N1CCCC1=O)C2)c1ccccc1.[Cl-],,CC#N,CCOC(C)=O,,,test
US20040019072A1,CCCCCCCOc1c(C(C)=CC=CC(C)=CC(=O)[O-])cc(C(C)C)cc1C(C)C>>CCCCCCCOc1c(C(C)=CC=CC(C)=CC(=O)O)cc(C(C)C)cc1C(C)C,,CO,,Cl,[Na+].[OH-],test
US20050070589A1,C1COCCN1.CCCCCc1ccc(S(=O)(=O)NCCc2c(-c3cccs3)n[nH]c2-c2ccnc(Cl)c2)cc1>>CCCCCc1ccc(S(=O)(=O)NCCc2c(-c3cccs3)n[nH]c2-c2ccnc(N3CCOCC3)c2)cc1,,CN1CCCC1=O,,,,test
US20070105864A1,CC(C)(C)OC(=O)N1CCC(O)CC1.O=[N+]([O-])c1cccc(F)c1>>CC(C)(C)OC(=O)N1CCC(Oc2cccc([N+](=O)[O-])c2)CC1,,CS(C)=O,,[H-].[Na+],,test
US20070069197A1,CCCCCCc1ccc2c3ccc(CO)cc3n(C)c2c1>>CCCCCCc1ccc2c3ccc(C=O)cc3n(C)c2c1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US05534518,Cc1c(Br)ccc(N)c1C#N.OB(O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1c(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)ccc(N)c1C#N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O,O=C([O-])[O-].[K+].[K+],test
US20150111876A1,Cc1nc(CNC(C)(C)CO)c2cc(C3CCCCC3)sc2n1.O=C(n1ccnc1)n1ccnc1>>Cc1nc(CN2C(=O)OCC2(C)C)c2cc(C3CCCCC3)sc2n1,,ClCCl,,,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Nc1ccc2c(c1)OCCO2>>COc1ccc2nc(Nc3ccc4c(c3)OCCO4)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US20090298744A1,CCOC(=O)c1cn[nH]c1.CS(=O)(=O)OC1CC(=O)N(c2cccc(C(F)(F)F)c2)C1>>CCOC(=O)c1cnn(CC2CC(=O)N(c3cccc(C(F)(F)F)c3)C2)c1,,CCCCCC,CCOC(C)=O,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US05641793,CN(C)c1cccc2c(S(=O)(=O)Cl)cccc12.Cc1cc(Br)cnc1N>>Cc1cc(Br)cnc1NS(=O)(=O)c1cccc2c(N(C)C)cccc12,CN(C)c1ccncc1,c1ccncc1,,,,test
US20110118230A1,COC(=O)c1c(CN(CC#N)S(=O)(=O)c2ccc(C)cc2)n(S(=O)(=O)c2ccccc2)c2ncc(Br)cc12>>N#Cc1ncc2c(c1O)c1cc(Br)cnc1n2S(=O)(=O)c1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04537891,COc1cccc(Cc2cnc(SC)[nH]c2=O)c1.Cc1cc(Br)cnc1CCCCN>>COc1cccc(Cc2cnc(NCCCCc3ncc(Br)cc3C)[nH]c2=O)c1,,c1ccncc1,,,,test
US20140066432A1,CCOC(=O)C1=Cc2cc(Br)ccc2N=C(N)C1.OB(O)c1cccc(C(F)(F)F)c1>>CCOC(=O)C1=Cc2cc(-c3cccc(C(F)(F)F)c3)ccc2N=C(N)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060052431A1,CC(N)Cc1n[nH]c2ccc(O)cc12.O=C(Cl)OCC1c2ccccc2-c2ccccc21>>CC(Cc1n[nH]c2ccc(O)cc12)NC(=O)OCC1c2ccccc2-c2ccccc21,,O,,C1COCCO1,O=C([O-])O.[Na+],test
US20040171634A1,C[Si](C)(C)CCOCn1ccnc1CO.O=S(Cl)Cl>>C[Si](C)(C)CCOCn1ccnc1CCl.Cl,,ClC(Cl)Cl,,,,test
US20080070920A1,O=C(O)c1ccncc1F>>OCc1ccncc1F,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150005279A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.NC(=O)c1ccc(Br)c2cc[nH]c12>>CC1(C)OB(c2ccc(C(N)=O)c3[nH]ccc23)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20150210690A1,CCOC(=O)[C@H](CO)C[C@@H](Cc1ccc(-c2cc(Cl)ccc2F)cc1)NC(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CCOC(=O)[C@H](COS(C)(=O)=O)C[C@@H](Cc1ccc(-c2cc(Cl)ccc2F)cc1)NC(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20090298823A1,CCCCOC(=O)C1CCCN(c2nc(Nc3ccc(N4CCN(C(C)=O)CC4)cc3)nc3[nH]cnc23)C1>>CC(=O)N1CCN(c2ccc(Nc3nc(N4CCCC(C(=O)O)C4)c4nc[nH]c4n3)cc2)CC1,,C1CCOC1,,CC(=O)O,[Li+].[OH-],test
US20150141433A1,COC(=O)c1ccc(C)nn1.O=C1CCC(=O)N1Br>>COC(=O)c1ccc(CBr)nn1,,CN(C)C=O,O,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20100226853A1,Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCNCC2)n1.FCCBr>>Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCF)CC2)n1,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US20100197725A1,CCCC(CCC)N1CCc2c(C(=O)OC)cc(N)cc2C1=O.CS(=O)(=O)Cl>>CCCC(CCC)N1CCc2c(C(=O)OC)cc(NS(C)(=O)=O)cc2C1=O,,ClCCl,O,c1ccncc1,O=C([O-])O.[Na+],test
US20050256158A1,CC(C)(C)OC(=O)NC(CCO)C(=O)O.CO>>COC(=O)C(CCO)NC(=O)OC(C)(C)C,,CO,,C[Si](C)(C)C=[N+]=[N-],,test
US20050239683A1,CC(C)=CCC1(C)CCC=C(C)C1=O>>CC12CCC3C(C1)C(C)(C)C3(C)C2=O,,CO,,,,test
US20030100753A1,COc1cc([N+](=O)[O-])c(C#N)c(I)c1OC>>COc1cc(N)c(C#N)c(I)c1OC,,CCO,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20020061996A1,CC(C)(CO)CO.CCCOc1cc(C=O)ccc1OCc1ccccc1>>CCCOc1cc(C2OCC(C)(C)CO2)ccc1OCc1ccccc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100103366A1,C=C(C)C(=O)O.CCCCCC1CCC(C2CCC(C(=O)OCCCCCCBr)CC2)CC1>>C=C(C)C(=O)OCCCCCCOC(=O)C1CCC(C2CCC(CCCCC)CC2)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US20030004173A1,CCCOc1ccc(S(=O)(=O)N2CCN(CC)CC2)cc1-c1nc2ncn(-c3ccc([N+](=O)[O-])cc3)c2c(=O)[nH]1>>CCCOc1ccc(S(=O)(=O)N2CCN(CC)CC2)cc1-c1nc2ncn(-c3ccc(N)cc3)c2c(=O)[nH]1,[Fe],CC(=O)O,O,,,test
US20090298883A1,CCS(=O)(=O)Cl.NC1(CN2CCC(CNC(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC2)CCCC1>>CCS(=O)(=O)NC1(CN2CCC(CNC(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC2)CCCC1,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20110124661A1,OCc1ccccc1.Oc1ccc(Br)nc1>>Brc1ccc(OCc2ccccc2)cn1,,ClCCl,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160024016A1,CN(CCN(C)C(=O)OC(C)(C)C)Cc1cn(C2CCCCO2)nc1C1=C[C@@H](O[Si](C)(C)C(C)(C)C)C(C)(C)CC1>>CN(CCN(C)C(=O)OC(C)(C)C)Cc1cn(C2CCCCO2)nc1C1CCC(C)(C)[C@H](O[Si](C)(C)C(C)(C)C)C1,,CCO,,,,test
US20100297079A1,CNC.C[C@@]1(O)C(O)C(CO)O[C@H]1n1cc(-c2cc(C(=O)O)cs2)c2c(N)ncnc21.ClCCCl.On1nnc2ccccc21>>CN(C)C(=O)c1csc(-c2cn([C@@H]3OC(CO)C(O)[C@@]3(C)O)c3ncnc(N)c23)c1.ClCCCl.On1nnc2ccccc21,,CN(C)C=O,,C1CCOC1,CCN(C(C)C)C(C)C,test
US20080064682A1,CCN(CC)S(F)(F)F.O=C(c1ccccc1)N1CCC[C@H]1CO>>O=C(c1ccccc1)N1CCC[C@H]1CF,,ClCCl,,,,test
US20120142671A1,Cc1cc(Nc2cc(N[C@H](Cc3c[nH]c4ccccc34)C(N)=O)ccc2C#N)sn1.OO>>Cc1cc(Nc2cc(N[C@H](Cc3c[nH]c4ccccc34)C(N)=O)ccc2C(N)=O)sn1,,CCO,CS(C)=O,CC(=O)O,[Na+].[OH-],test
US20070099929A1,COC(=O)c1cc(Br)sc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C(C)C.OB(O)c1ccc(F)cc1>>COC(=O)c1cc(-c2ccc(F)cc2)sc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C(C)C,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20160039834A1,Cc1noc(C)c1-c1nc(-c2cc(OC[C@@H](CN(C)C(=O)OC(C)(C)C)O[Si](C)(C)C(C)(C)C)ccc2Cl)nc(N2Cc3cc(F)cnc3C2)c1C>>CNC[C@@H](O)COc1ccc(Cl)c(-c2nc(-c3c(C)noc3C)c(C)c(N3Cc4cc(F)cnc4C3)n2)c1,,C1COCCO1,Cl,,,test
US04413010,CCOC(=O)N(C)CCCl.Oc1ccc(Oc2ccccc2)cc1>>CCOC(=O)N(C)CCOc1ccc(Oc2ccccc2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150315160A1,CC(C)(C)OC(=O)Nc1conc1-c1ccc(OCc2ccc(F)cc2)cc1>>Nc1conc1-c1ccc(OCc2ccc(F)cc2)cc1,,C1COCCO1,,CCOCC,Cl,test
US20030158226A1,CC1(C)CCC(C)(C)c2cc(N)ccc21.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC1(C)CCC(C)(C)c2cc(NC(=O)C(F)(F)F)ccc21,,CCOC(C)=O,c1ccncc1,,,test
US20100273764A1,CC(C)OB(OC(C)C)OC(C)C.COCCOc1ccc(F)nc1>>COCCOc1cnc(F)c(B(O)O)c1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20140045828A1,C[N+](=O)[O-].O=CC1CCCCC1>>O=[N+]([O-])CC(O)C1CCCCC1,,CCO,,CC(=O)O,[Na+].[OH-],test
US20110312952A1,C[Si](C)(C)[O-].NC(=O)c1c(F)cccc1C(F)(F)F>>NC(=O)c1c(O)cccc1C(F)(F)F,,COCCOCCOC,,Cl,,test
US20140206618A1,CN(C)C=O.COc1c(Br)ccc(F)c1C(=O)O>>COc1c(Br)ccc(F)c1C(N)=O,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20150087639A1,ClCCCn1cnnn1.Nc1ccc([N+](=O)[O-])cc1F>>O=[N+]([O-])c1ccc(NCCCn2cnnn2)c(F)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100286210A1,CC(=O)/C(C)=N/O.O=Cc1ccccc1>>Cc1oc(-c2ccccc2)[n+]([O-])c1C,,CC(=O)O,,Cl,[Na+].[OH-],test
US20100197683A1,CC(C)(C)[Si](C)(C)OC1CCC(=O)CC1.Nc1cnnn1Cc1ccccc1>>CC(C)(C)[Si](C)(C)OC1CCC(Nc2cnnn2Cc2ccccc2)CC1,,CC(=O)O,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150045351A1,CC(=O)Cl.CC(C)(C)OC(=O)N1CCc2cccc3c2C(CN3)C1>>CC(=O)N1CC2CN(C(=O)OC(C)(C)C)CCc3cccc1c32,,O,,CC(=O)N(C)C,,test
US20030166686A1,CC(C)(C)[Si](C)(C)Cl.O[C@@H](CBr)c1cccnc1>>CC(C)(C)[Si](C)(C)[C@@H](CBr)c1cccnc1,,CN(C)C=O,ClC(Cl)Cl,O,c1c[nH]cn1,test
US20080214641A1,CCOC(=O)CN=C=O.C[C@H](N)[C@H](Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1>>CCOC(=O)CNC(=O)N[C@@H](C)[C@H](Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1,,ClCCl,,,,test
US20160152543A1,C=C(C)c1ccc(C)c(C(OC(C)(C)C)C(=O)OC)c1-c1ccc2c(c1)CCCO2>>COC(=O)C(OC(C)(C)C)c1c(C)ccc(C(C)C)c1-c1ccc2c(c1)CCCO2,[Pd],CO,,,,test
US20130126856A1,CC1(C)C2=C(C=C3N=c4ccccc4=C31)C(Br)=C1C=CC(c3ccc(-c4ccccc4)cc3)C=C12.CC1(C)OB(c2ccc3c(c2)c2ccccc2n3-c2ccccc2)OC1(C)C>>CC1(C)C2=C(C=C3N=c4ccccc4=C31)C(c1ccc3c(c1)c1ccccc1n3-c1ccccc1)=C1C=CC(c3ccc(-c4ccccc4)cc3)C=C12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],,test
US04129436,CON(C)C(=O)Nc1ccc(O)cc1.COc1ccc(CCBr)cc1>>COc1ccc(CCOc2ccc(NC(=O)N(C)OC)cc2)cc1,,CN(C)C=O,,C,C[O-].[Na+],test
US20160081340A1,CCOc1c(C=O)c(-c2ccc(OCc3ccccc3-n3nnn(C)c3=O)c(C)c2)nn1C>>CCOc1c(C)c(-c2ccc(OCc3ccccc3-n3nnn(C)c3=O)c(C)c2)nn1C,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20090047246A1,CCOC(=O)Cc1c[nH]c2cc(Br)ccc12.Clc1ccc2scc(CBr)c2c1>>CCOC(=O)Cc1cn(Cc2csc3ccc(Cl)cc23)c2cc(Br)ccc12,,CN(C)C=O,O,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20120277237A1,CNc1c(Cl)cccc1[N+](=O)[O-]>>CNc1c(N)cccc1Cl,[Fe],CCO,O,CC(=O)O,,test
US20160207905A1,CC(C)(C)OC(=O)NC1CCCC(CO)C1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)NC1CCCC(CN2C(=O)c3ccccc3C2=O)C1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120028961A1,COC(=O)c1ccc(C#N)cc1F>>N#Cc1ccc(C(=O)O)c(F)c1,,CCO,O,[K+].[OH-],,test
US20100272680A1,COC(=O)C(=O)CBr.Nc1ncccc1C(F)(F)F>>COC(=O)c1cn2cccc(C(F)(F)F)c2n1,,CN(C)C=O,,,,test
US20120277240A1,CC(C)(C)OC(=O)N[C@H]1C[C@@H](N2Cc3n[nH]c(C(N)=O)c3C2)CSC1c1cc(F)ccc1F>>CC(C)(C)OC(=O)N[C@H]1C[C@@H](N2Cc3n[nH]c(C#N)c3C2)CSC1c1cc(F)ccc1F,,c1ccncc1,,O=P(Cl)(Cl)Cl,,test
US04843068,Cc1nn(C)c(Oc2ccccc2)c1C=NOCc1ccc(C(=O)O)cc1.Oc1ccccc1>>Cc1nn(C)c(Oc2ccccc2)c1C=NOc1ccc(C(=O)Oc2ccccc2)cc1,,CCOCC,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090124613A1,O=C1c2ccccc2C(=O)N1CCC1(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)OCCc2ccccc21>>NCCC1(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)OCCc2ccccc21,,CCO,CCOCC,NN,,test
US20150368245A1,CC(C)(C)[Si](C)(C)Cl.C[Si](C)(C)CCOCn1ccc2c(N[C@@H]3CC[C@@H](CO)CC3)c(C(N)=O)cnc21>>CC(C)(C)[Si](C)(C)OC[C@@H]1CC[C@@H](Nc2c(C(N)=O)cnc3c2ccn3COCC[Si](C)(C)C)CC1,,CN(C)C=O,,O,c1c[nH]cn1,test
US20100093798A1,CC(C)(C)OC(=O)N1CCC(C(=O)CCl)CC1.NC(=O)Nc1cc(Cl)ccc1O>>CC(C)(C)OC(=O)N1CCC(C(=O)COc2ccc(Cl)cc2NC(N)=O)CC1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20020082254A1,Cc1ccccc1OC(=O)Cl.NN1CCc2ccccc2C1>>Cc1ccccc1OC(=O)NN1CCc2ccccc2C1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US04698337,Nc1nc(C(=NOCCO)C(=O)NC2C(=O)N3C(C(=O)O)=C(CSc4nncs4)CS[C@H]23)cs1>>Nc1nc(C(=NOCCO)C(=O)NC2C(=O)N3C(C(=O)O)=C(CSc4nncs4)CS[C@H]23)cs1,,O,,Cl,,test
US05902801,Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O.O=S(=O)([O-])[O-].[Mn+2]>>N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O.O=S(=O)([O-])[O-].[Cl-].[Mn+3],,O,,,,test
US04680300,Clc1ccc2c(Cl)ccnc2c1.NCCCCCCN>>NCCCCCCc1ccnc2cc(Cl)ccc12,,ClCCl,,O,,test
US04457862,CC1CC(=O)CC(C)C1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)C=C1CC(C)CC(C)C1,,Cc1ccccc1,,[Na],,test
US06335332B1,CCO.O=C([O-])Cc1ccc(Oc2ccccc2)cc1>>CCOC(=O)Cc1ccc(Oc2ccccc2)cc1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20070010670A1,S=C(c1cc(Cl)c(OCc2ccccc2)c(Cl)c1)N1CCOc2ccccc21>>Oc1c(Cl)cc(C(=S)N2CCOc3ccccc32)cc1Cl,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US05585394,NC1CCCC1.O=[N+]([O-])c1ccc(Cl)cc1[N+](=O)[O-]>>O=[N+]([O-])c1ccc(Cl)cc1NC1CCCC1,,CCO,,,,test
US20130089512A1,ClC[C@@H]1CO1.N#Cc1ccc2ncc(-c3ncc4[nH]c(=O)n(C5CCOCC5)c4n3)n2c1>>N#Cc1ccc2ncc(-c3ncc4c(n3)n(C3CCOCC3)c(=O)n4C[C@@H]3CO3)n2c1,,CN(C)C=O,,[H-].[Na+],,test
US06048868,CCOC(=O)CCCC(=O)OCC.COc1ccc2[nH]cc(CCN)c2c1>>COc1ccc2[nH]c3c(c2c1)CCN1C(=O)CCC=C31,,CCOC(C)=O,,,,test
US20070219181A1,O=S(Cl)Cl.OCCCNc1ccc(F)cc1>>Fc1ccc(NCCCCl)cc1,,Cc1ccccc1,,,,test
US20160002225A1,CCNC(=O)Nc1ccc(Oc2ccnc3[nH]nc(N[C@@H]4CCCNC4)c23)cc1.CN(C/C=C/C(=O)O)C1CC1>>CCNC(=O)Nc1ccc(Oc2ccnc3[nH]nc(N[C@@H]4CCCN(C(=O)/C=C/CN(C)C5CC5)C4)c23)cc1,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US06479670B1,CCOC(=O)c1ccc(CP(=O)(OCC)OCC)cc1.CCOCC1(C)CCCSc2cc(C=O)ccc21>>CCOCC1(C)CCCSc2cc(/C=C/c3ccc(C(=O)O)cc3)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US04284631,CCOC(=O)C(=NOCc1ccc(Cl)cc1)C(=O)CCl.NC(N)=S>>CCOC(=O)C(=NOCc1ccc(Cl)cc1)c1csc(N)n1,,CCO,,O,CC(=O)[O-].[Na+],test
US20040209921A1,Cc1cccnc1CN(Cc1ncccc1C)C1CCNCC1.N#CBr>>Cc1cccnc1CN(Cc1ncccc1C)C1CCN(C#N)CC1,,CO,,O,CC(=O)[O-].[Na+],test
US20160264594A1,C=C1[C@H](C)C[C@H](CC[C@@H]2O[C@@H](/C=C/C=O)CC2=C)O[C@@H]1C[C@@H]1O[C@H](C[C@@H](CO[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@H](OC)[C@H]1CS(=O)(=O)c1ccccc1>>C=C1[C@H](C)C[C@H](CC[C@@H]2O[C@@H](/C=C/CO)CC2=C)O[C@@H]1C[C@@H]1O[C@H](C[C@@H](CO[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@H](OC)[C@H]1CS(=O)(=O)c1ccccc1,,C1CCOC1,Cc1ccccc1,CC(C)C[AlH]CC(C)C,,test
US06600042B1,Nc1cc(O)nc(N)n1.Nc1nc(N)c(N=O)c(N)n1>>c1ncc2nc3cncnc3nc2n1,,CC(=O)O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20110251190A1,COc1cc(F)c2oc3cc(F)c(Br)cc3c(=O)c2c1.C[Mg]Cl>>COc1cc(F)c2c(c1)C(C)(O)c1cc(Br)c(F)cc1O2,,C1CCOC1,,,,test
US04337270,COc1ccc(C=CC(=O)Cl)cc1OC.Nc1ccc(Cl)cc1C(=O)O>>COc1ccc(C=CC(=O)Nc2ccc(Cl)cc2C(=O)O)cc1OC,,CCN(CC)CC,ClC(Cl)Cl,,,test
US20100197749A1,CC(=O)NN.O=C(O)[C@H](Cc1ccccc1)NS(=O)(=O)c1ccc(Cl)cc1>>CC(=O)N(N)C(=O)C(Cc1ccccc1)NS(=O)(=O)c1ccc(Cl)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140206663A1,CCOC(=O)C(C)Br.Cc1cc2c(cc1[N+](=O)[O-])NC(=O)CO2>>CCOC(=O)C(C)N1C(=O)COc2cc(C)c([N+](=O)[O-])cc21,,CC(C)=O,O,CC#N,O=C([O-])[O-].[K+].[K+],test
US05212187,CN(CCCCN)CCC(c1ccc(Cl)cc1)c1ccccn1.N#CNC(=NCCCOc1cccc(CN2CCCCC2)c1)Oc1ccccc1>>CN(CCCCNC(=NCCCOc1cccc(CN2CCCCC2)c1)NC#N)CCC(c1ccc(Cl)cc1)c1ccccn1,,CO,ClCCl,,,test
US20080176829A1,C=O.CC1NCCOc2ccc3c(c(Cl)cn3S(=O)(=O)c3ccccc3)c21>>CC1c2c(ccc3c2c(Cl)cn3S(=O)(=O)c2ccccc2)OCCN1C,,C1CCOC1,CO,O=C(O)C(F)(F)F,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130281490A1,C[C@H](O)[C@@H](NC(=O)OCCCCCC1CCCCC1)C(=O)O>>C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCCC1CCCCC1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20100130497A1,CCC#CCCOc1cc(C=O)ccc1OC.O=C(O)CC(=O)Nc1ccccc1C(=O)O>>CCC#CCCOc1cc(/C=C/C(=O)Nc2ccccc2C(=O)O)ccc1OC,,Cc1ccccc1,,C1CCNCC1,Cl,test
US05631401,CC(=O)Cl.c1ccc2c(c1)oc1ccccc12>>CC(=O)c1ccc2oc3ccccc3c2c1,,CC(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20010034357A1,C=Cc1ccnc(-c2cc(OC[C@H](C)N)cnc2Cl)c1.Cc1ccc(S(=O)(=O)O)cc1>>C=Cc1ccnc(-c2cc(OC[C@H](C)N)cnc2Cl)c1.Cc1ccc(S(=O)(=O)O)cc1,,CCOC(C)=O,,CCOCC,O,test
US04539319,Brc1ccc(OCc2ccccc2)c2c1CCCC2.CN(C)P(=O)(N(C)C)N(C)C>>N#CC1(OCc2ccccc2)CC=CC2=C1CCCC2,,ClCCl,,,,test
US20160031811A1,BrC(Br)(Br)Br.ClCCl.O=C([O-])c1ccc(C#CCO)s1>>COC(=O)c1ccc(C#CCBr)s1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110071150A1,CCOC(=O)n1c(-c2ccncc2F)cc2cc(-c3nc(-c4ccccn4)sc3C)ccc21>>Cc1sc(-c2ccccn2)nc1-c1ccc2[nH]c(-c3ccncc3F)cc2c1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20140323504A1,Cn1cc(N)cn1.O=[N+]([O-])c1cccc(Cn2ncc3cnc(Cl)nc32)c1>>Cn1cc(Nc2ncc3cnn(Cc4cccc([N+](=O)[O-])c4)c3n2)cn1,,CC(C)O,,Cl,,test
US20070066618A1,CCC(=O)OCCc1ccc(-n2c(CC)nc3c(C)c(N)cnc32)cc1.CS(=O)(=O)Cl>>CCC(=O)OCCc1ccc(-n2c(CC)nc3c(C)c(NS(C)(=O)=O)cnc32)cc1,,ClCCl,,c1ccncc1,,test
US20100105700A1,C[C@]12CC[C@H]3[C@@H](CCC(=O)[C@]3(C)CCC(=O)O)[C@@H]1CCC2=O.NC1CC1>>C[C@]12CC[C@H]3[C@@H](CC=C4N(C5CC5)C(=O)CC[C@@]43C)[C@@H]1CCC2=O,,OCCO,,,,test
US20120015975A1,CN.FC(F)(F)c1ccc(Cl)nc1>>CNc1ccc(C(F)(F)F)cn1,,O,,CN1CCCC1=O,,test
US20090186879A1,COc1ccc([N+](=O)[O-])c(C)n1>>COc1ccc(N)c(C)n1,[Pd],CO,,,,test
US06048852,CI.O=CC(=O)O.c1ccoc1>>COC(=O)C(=O)c1ccco1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05902814,CC(C)(C)OC(=O)CC1(O)CN2CCC1CC2.NN>>NNC(=O)CC1(O)CN2CCC1CC2,,CO,ClCCl,O=C(O)C(F)(F)F,,test
US20090176756A1,CC(C)(C)OC(=O)NC1CCN(c2nccs2)C1.Cl>>Cl.NC1CCN(c2nccs2)C1,,CO,,,,test
US20120238559A1,C[Sn](C)(C)c1cc(N)c2c(F)nn(S(=O)(=O)c3ccccc3)c2c1.Cc1cc2c(Br)ccnc2n1S(=O)(=O)c1ccccc1>>Cc1cc2c(-c3cc(N)c4c(F)nn(S(=O)(=O)c5ccccc5)c4c3)ccnc2n1S(=O)(=O)c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US20030130213A1,N#Cc1cncc(F)n1.O>>NC(=O)c1cncc(F)n1,,Cl,,CCOC(C)=O,,test
US20060116410A1,N#Cc1ccc(CNC(=O)c2cccc(F)c2)c(O)c1.NC(=O)CI>>N#Cc1ccc(CNC(=O)c2cccc(F)c2)c(OCC(N)=O)c1,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05006536,COC(OC)c1ccsc1.O=Cc1ccccc1F>>COC(OC)c1ccsc1C(O)c1ccccc1F,,C1CCOC1,,CCOCC,[Li]CCCC,test
US04556669,CC1=C(C(=O)Nc2ccccc2)SC2=NCCN21>>CC1=C(C(=O)Nc2ccccc2)SC2=NCCN21,,O,,CCN(CC)CC,Cl,test
US04725610,ClCc1coc(-c2ccccc2)n1.O=C1NC(=O)C(Cc2ccc(O)cc2)S1>>O=C1NC(=O)C(Cc2ccc(OCc3coc(-c4ccccc4)n3)cc2)S1,,CN(C)C=O,,O,[H-].[Na+],test
US20090118279A1,C[Si](C)(C)CCOCn1ccnc1CC(CO)Cc1nccn1COCC[Si](C)(C)C.O=Cc1ccc(O)cc1>>C[Si](C)(C)CCOCn1ccnc1CC(COc1ccc(C=O)cc1)Cc1nccn1COCC[Si](C)(C)C,,C1CCOC1,O,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05985873,CC1CCC(c2cccc(NC(=O)N3CCC4(CC3)OCCO4)c2)(N2CCN(c3ccccc3)CC2)CC1>>CC1CCC(c2cccc(NC(=O)N3CCC(=O)CC3)c2)(N2CCN(c3ccccc3)CC2)CC1,,Cl,,[Na+].[OH-],,test
US20040024218A1,BrCc1ccccc1.O=C1CC(C(=O)N2CCC(c3ccccc3)CC2)CCc2c(O)cccc21>>O=C1CC(C(=O)N2CCC(c3ccccc3)CC2)CCc2c(OCc3ccccc3)cccc21,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20100087438A1,COc1cccc(N)c1.O=Cc1ccc(Cl)cc1>>COc1cccc(NCc2ccc(Cl)cc2)c1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100204196A1,CCNCC.COc1cc2c(cc1[N+](=O)[O-])NCC2.O=C(Cl)CBr>>CCN(CC)CC(=O)N1CCc2cc(OC)c([N+](=O)[O-])cc21,,C1CCOC1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20020177606A1,COc1ccc2ncc(F)c(C(O)CCC3CCN(C(=O)OC(C)(C)C)CC3CC(=O)O)c2c1.O=S(Cl)Cl>>COc1ccc2ncc(F)c(C(O)CCC3CCNCC3CC(=O)O)c2c1.Cl.Cl,,CO,,,,test
US20030187014A1,COC(=O)c1ccc2[nH]c3c(c(C)nn3-c3ccccn3)c(=O)c2c1>>Cc1nn(-c2ccccn2)c2[nH]c3ccc(C(=O)O)cc3c(=O)c12,,CCO,,Cl,[Na+].[OH-],test
US04027038,O=C(Nc1ccc2c(S(=O)(=O)[O-])cccc2c1S(=O)(=O)[O-])c1cccc([N+](=O)[O-])c1.[Na+].[Na+]>>Nc1cccc(C(=O)Nc2ccc3c(S(=O)(=O)[O-])cccc3c2S(=O)(=O)[O-])c1.[Na+].[Na+],[Pd],O,,[H][H],,test
US20140228360A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1cc(CNC2CCCC2)cc(OCC2CO2)c1>>CC(C)(C)OC(=O)N(Cc1cccc(OCC2CO2)c1)C1CCCC1,,C1CCOC1,,,,test
US20120015962A1,CCOC(=O)c1c[nH]c2c(C)csc2c1=O>>CCOC(=O)c1cnc2c(C)csc2c1,,CCOC(C)=O,,O=P(Cl)(Cl)Cl,,test
US06521627B1,CC(=O)OC(C)c1ncnc(Cl)c1I.NCCc1ccccc1>>CC(=O)OC(C)c1ncnc(NCCc2ccccc2)c1I,,Cc1ccccc1,,CCN(CC)CC,,test
US20120108535A1,CC(C)[Si](OC[C@H]1OC(O)[C@@H](F)[C@@H]1O[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C.CS(=O)(=O)Cl>>CC(C)[Si](OC[C@H]1OC(O)(Cl)[C@@H](F)[C@@H]1O[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C,,ClCCl,,CCN(CC)CC,,test
US20160009744A1,CC(C)[Si](O[C@H]1C[C@H](Nc2ncncc2C(=O)c2cc(CBr)cs2)C[C@@H]1CO[Si](C)(C)C(C)(C)C)(C(C)C)C(C)C.FC1(F)CCNC1>>CC(C)[Si](O[C@H]1C[C@H](Nc2ncncc2C(=O)c2cc(CN3CCC(F)(F)C3)cs2)C[C@@H]1CO[Si](C)(C)C(C)(C)C)(C(C)C)C(C)C,,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US20130210844A1,Nc1cccc(C(F)(F)F)c1.O=[N+]([O-])c1cccc2c(Cl)ncnc12>>O=[N+]([O-])c1cccc2c(Nc3cccc(C(F)(F)F)c3)ncnc12,,CC(C)O,,,,test
US20100197665A1,O=C(Nc1nn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ccc(S(=O)(=O)c3cc(F)cc(F)c3)cc12)c1ccc(C(=O)N2CCC(N3CCCC3)CC2)cc1>>O=C(Nc1n[nH]c2ccc(S(=O)(=O)c3cc(F)cc(F)c3)cc12)c1ccc(C(=O)N2CCC(N3CCCC3)CC2)cc1,,C1COCCO1,,CO,Cl,test
US20050203095A1,CC(C)(C)OC(=O)NN=Cc1ccc2ccccc2n1>>CC(C)(C)OC(=O)NNCc1ccc2ccccc2n1,[Pd],CO,,,,test
US20150119435A1,CC(C)(C)OC(=O)NCCOCCO.O=C(O)CC12CC3CC(CC(C3)C1)C2>>CC(C)(C)OC(=O)NCCOCCOC(=O)CC12CC3CC(CC(C3)C1)C2,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20120142665A1,Cc1c(C(=O)O)ccn2nc(-c3ccccc3)nc12.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>Cc1c(N)ccn2nc(-c3ccccc3)nc12,,CC(C)(C)O,,CCN(CC)CC,,test
US20090041723A1,Cn1cc(C#Cc2ccc(NC(=O)C3COCCN3C(=O)C(N)c3ccccc3)cc2)c(-c2cc(Cl)ccc2O)n1.O=C(Cl)N1CCOCC1>>Cn1cc(C#Cc2ccc(NC(=O)C3COCCN3C(=O)C(NC(=O)N3CCOCC3)c3ccccc3)cc2)c(-c2cc(Cl)ccc2O)n1,,ClCCl,,CCN(CC)CC,,test
US20090270452A1,CC(C)(C)OC(=O)NCCCCCC=O.CCOC(=O)C(F)P(=O)(OCC)OCC>>CCOC(=O)/C(F)=C/CCCCCNC(=O)OC(C)(C)C,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US05216167,CCOC(=O)c1ccc(CC(=O)NC(CC(C)C)c2ccccc2N2CCCCC2)cc1OCC>>CCOc1cc(CC(=O)NC(CC(C)C)c2ccccc2N2CCCCC2)ccc1C(=O)O,,CCO,,Cl,[Na+].[OH-],test
US20110092590A1,C=CCCCC(=O)O.CC(C)(C)O.ClCCl>>C=CCCCC(=O)OCCCC,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04638067,CCNCC1CCNC1.O=C(O)c1cn(C2CCCCC2)c2c(F)c(F)c(F)cc2c1=O>>CCNCC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CCCCC4)c3c2F)C1,,CC#N,,,,test
US20050282875A1,CN1CC[C@@H](O)C1.COC(=O)C(O)(c1ccco1)C1CCCCC1>>CN1CC[C@@H](OC(=O)C(O)(c2ccco2)C2CCCCC2)C1,,Cc1ccccc1,,,,test
US20100234341A1,C1COCCN1.Cc1cc(C)n(-c2nc(Cl)cc(NC(=O)CCl)n2)n1>>Cc1cc(C)n(-c2nc(Cl)cc(NC(=O)CN3CCOCC3)n2)n1,,ClCCl,,CC(C)NC(C)C,,test
US06265411B1,NCCN1CCOCC1.O=C1Cc2cc(S(=O)(=O)Cl)ccc2N1>>O=C1Cc2cc(S(=O)(=O)NCCN3CCOCC3)ccc2N1,,CCO,,,,test
US04806552,NC(=O)NC(=O)c1ccco1.NC1CCN(Cc2ccc3ccccc3c2)CC1>>O=C(NC(=O)c1ccco1)NC1CCN(Cc2ccc3ccccc3c2)CC1,,c1ccncc1,,O,,test
US04808593,Cc1ccc2c(n1)Oc1ccc(C(C)C(=O)O)cc1C2.NC(=O)CCCl>>Cc1ccc2c(n1)Oc1ccc(C(C)C(=O)OCCC(N)=O)cc1C2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040082551A1,C[C@@H](N)c1ccccc1.O=C1CCC(c2[nH]nc(-c3ccc(Cl)cc3)c2-c2ccncn2)CC1>>C[C@@H](N[C@@H]1CC[C@@H](c2[nH]nc(-c3ccc(Cl)cc3)c2-c2ccncn2)CC1)c1ccccc1,,C1CCOC1,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05622951,COc1ccccc1N1CCN(C2CCC(O)(c3ccc(C)cc3C)CC2)CC1>>COc1ccccc1N1CCN([C@@H]2CC[C@@H](c3ccc(C)cc3C)CC2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020055497A1,CN(C)c1ccc2c(n1)n(C1CCN(C(=O)OC(C)(C)C)CC1)c(=O)n2C>>CN(C)c1ccc2c(n1)n(C1CCNCC1)c(=O)n2C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040044052A1,C[C@@H]1Cc2cc(NC(=O)OCc3ccccc3)ccc2N1C(=O)OCc1ccccc1>>C[C@@H]1Cc2cc(N)ccc2N1,[Pd],C1CCOC1,CO,[H][H],,test
US20110034461A1,CC(=O)OC(C)=O.CC(=O)c1cc(N)cc(S(F)(F)(F)(F)F)c1>>CC(=O)Nc1cc(C(C)=O)cc(S(F)(F)(F)(F)F)c1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US05026856,CC(=O)NCc1ccc2c(c1)CN(c1cc3c(cc1F)c(=O)c(C(=O)O)cn3C1CC1)C2.Cl>>Cl.NCc1ccc2c(c1)CN(c1cc3c(cc1F)c(=O)c(C(=O)O)cn3C1CC1)C2,,CCO,,O,,test
US20070185133A1,CC(=O)CCC(C)=O.Nc1ccc2sccc2c1>>Cc1ccc(C)n1-c1ccc2sccc2c1,,CCOCC,c1ccccc1,CC(=O)O,,test
US20130085132A1,NC1=NN(c2ccc(F)cc2)C(c2cccc(OC(F)(F)F)c2)C1>>Nc1cc(-c2cccc(OC(F)(F)F)c2)n(-c2ccc(F)cc2)n1,,Cc1ccccc1,,,,test
US20070072925A1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=C1CC(c2cccc(Br)c2)C1>>CCOC(=O)C=C1CC(c2cccc(Br)c2)C1,,ClCCl,,,,test
US20100056535A1,BrBr.COc1ncc(CO)c(Oc2cc(Cl)cc(C#N)c2)c1Br>>COc1ncc(CBr)c(Oc2cc(Cl)cc(C#N)c2)c1Br,,ClCCl,,c1c[nH]cn1,,test
US20020120148A1,CC(C)(C)OC(=O)N(Cc1ccccc1)C1CCCc2ccc(OC(F)(F)F)cc2C1.OB(O)c1ccccc1>>CC(C)(C)OC(=O)N(Cc1ccccc1)C1CCCc2ccc(-c3ccccc3)cc2C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20100056576A1,CB(O)O.COC(=O)c1ccc(F)c(-c2c(F)ccc(OS(=O)(=O)C(F)(F)F)c2F)n1>>Cc1ccc(F)c(-c2nc(C(=O)O)ccc2F)c1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US05969138,COCCN1CCN(C[C@H]2CCN(c3ccc(Cl)cc3)C2=O)CC1.C[C@H](O)C(=O)O>>COCCN1CCN(C[C@H]2CCN(c3ccc(Cl)cc3)C2=O)CC1.C[C@H](O)C(=O)O,,CCOC(C)=O,,,,test
US04059705,CCCCCC(Cl)CCn1ccnc1.CCCCCCCCS>>CCCCCCCCSC(CCCCC)CCn1ccnc1,,C1CCOC1,,[H-].[Na+],,test
US20160102071A1,CC#C[C@@H](CC(=O)OCC)c1ccc(OCc2ccc3scc(-c4cnccc4OC)c3c2)cc1>>CC#C[C@@H](CC(=O)O)c1ccc(OCc2ccc3scc(-c4cnccc4OC)c3c2)cc1,,CCO,,Cl,[Li+].[OH-],test
US06274583B1,CC(C)(C)OC(=O)NCCCBr.Cc1ccccc1C1(C#N)CCNCC1>>Cc1ccccc1C1(C#N)CCN(CCCNC(=O)OC(C)(C)C)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20160083362A1,CCI.Fc1cccc(CC2CC3CCC(C2)N3)c1>>CCN1C2CCC1CC(Cc1cccc(F)c1)C2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140336377A1,C1COCCN1.O=C(OCC(F)(F)F)c1ccc(OCC(F)(F)F)nc1Cl>>O=C(OCC(F)(F)F)c1ccc(OCC(F)(F)F)nc1N1CCOCC1,,C1CCOC1,,CCN(CC)CC,O,test
US08129361B2,O=C1CCC(=O)N1Br.OCCCc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>FC(F)(F)c1cc(CCCBr)cc(C(F)(F)F)c1,,ClCCl,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150065482A1,CCOC(=O)c1ncc2ccccn12>>CCOC(=O)c1ncc2n1CCCC2,[Pd],CO,,,,test
US20160185775A1,CC(C)(C)OC(=O)NC1(CN)CC1.Cc1cc(OCc2c(F)cccc2F)n2nc(C)c(C(=O)O)c2c1>>Cc1cc(OCc2c(F)cccc2F)n2nc(C)c(C(=O)NCC3(N)CC3)c2c1,,CN(C)C=O,ClCCl,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06281355B1,CCCCCCN(CCCCCC)C(=O)C1Sc2ccccc2-c2[nH]c3ccccc3c21.CI>>CCCCCCN(CCCCCC)C(=O)C1Sc2ccccc2-c2c1c1ccccc1n2C,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US04079179,CO[C@]12SCC(COC(C)=O)=C(C(=O)OCc3ccc([N+](=O)[O-])cc3)N1C(=O)C2N.O=C(Cl)Cc1cccs1>>CO[C@]12SCC(COC(C)=O)=C(C(=O)OCc3ccc([N+](=O)[O-])cc3)N1C(=O)C2NC(=O)Cc1cccs1,,ClCCl,,c1ccncc1,,test
US20090042854A1,C=C(O[C@H]1CN(C(=O)OC(C)(C)C)[C@@H](CO[Si](C)(C)C(C)(C)C)[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C[C@@H](O[C@H]1CN(C(=O)OC(C)(C)C)[C@@H](CO[Si](C)(C)C(C)(C)C)[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,[Pd],CCO,,,,test
US20120208732A1,C=CCCCCCCCC(=O)O.C=CCCCCCCCCO>>C=CCCCCCCCCOC(=O)CCCCCCCC=C,,CCCCCC,CCOC(C)=O,,,test
US20130190289A1,CNC.COCC(Nc1cc(C#CC(C)(C)C)sc1C(=O)OC)C(=O)O>>COCC(Nc1cc(C#CC(C)(C)C)sc1C(=O)OC)C(=O)N(C)C,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05380731,CC(C)(C)OC(=O)N1CCC(C(=O)c2nc3ccccc3[nH]2)CC1.COC(=O)COCCBr>>COC(=O)COC(C)n1c(C(=O)C2CCN(C(=O)OC(C)(C)C)CC2)nc2ccccc21,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080262036A1,CCC(O)c1sc(-c2ccc(C(F)(F)F)cc2)nc1C.N#Cc1ccc(F)cc1OC(F)F>>CCC(Oc1ccc(C#N)c(OC(F)F)c1)c1sc(-c2ccc(C(F)(F)F)cc2)nc1C,,CN(C)C=O,,O,[H-].[Na+],test
US05110812,CC(=O)OC1NC(=O)C1CCCNC(=NC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1.O=C(Cl)c1ccccc1>>CC(=O)OC1C(CCCNC(=NC(=O)OCc2ccccc2)NC(=O)OCc2ccccc2)C(=O)N1C(=O)c1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20070270471A1,CN1C[C@@H](c2ccc(N)cc2)[C@H]([N+](=O)[O-])C1.O=C(Cl)c1ccccc1>>CN1C[C@@H](c2ccc(NC(=O)c3ccccc3)cc2)[C@H]([N+](=O)[O-])C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070225324A1,CC(C)[C@H](C(=O)NC1CC1)n1ccc2c([N+](=O)[O-])cccc2c1=O>>CC(C)[C@H](C(=O)NC1CC1)n1ccc2c(N)cccc2c1=O,[Pd],,,CO,,test
US20060094733A1,CCOC(=O)C1CCCNC1.Cn1c(=O)c2c(nc(Br)n2Cc2c(F)cccc2Cl)n(C)c1=O>>CCOC(=O)C1CCCN(c2nc3c(c(=O)n(C)c(=O)n3C)n2Cc2c(F)cccc2Cl)C1,,CCOC(C)=O,CS(C)=O,ClCCl,O,test
US05166154,CCOC(=O)CN(C(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C1Cc2ccccc2C1>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N(CC(=O)O)C1Cc2ccccc2C1,,CCO,,[K+].[OH-],,test
US20030149001A1,CCOCCCC(=O)OCC.CSc1ncc(C=O)c(NC2CCCC2)n1>>CCOCCc1cc2cnc(SC)nc2n(C2CCCC2)c1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US06423689B1,CC(C)CC(NC(=O)N1CCCCCC1)C(=O)NC(Cc1ccc(OCc2cccc(NC(=O)OC(C)(C)C)c2)cc1)C(=O)OC(C)(C)C>>CC(C)CC(NC(=O)N1CCCCCC1)C(=O)NC(Cc1ccc(OCc2cccc(N)c2)cc1)C(=O)OC(C)(C)C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140221503A1,OCCCCCBr.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>OCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-],,CCO,,,,test
US20090324581A1,CC(C)(C)OC(=O)CCN(CC(=O)N1CCc2cc(OCc3cn(C4CCCCC4)nc3C(F)(F)F)ccc21)C(=O)OC(C)(C)C>>O=C(O)CCNCC(=O)N1CCc2cc(OCc3cn(C4CCCCC4)nc3C(F)(F)F)ccc21,,ClCCl,O=C(O)C(F)(F)F,,,test
US20160168156A1,CCOC(=O)c1cnn2ccc(Cl)nc12.Fc1ccc(F)c([C@H]2CCCN2)c1>>CCOC(=O)c1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nc12,,CS(C)=O,,[F-].[K+],,test
US20130281434A1,CC(Br)Br.Oc1ccc(Br)cc1O>>CC1Oc2ccc(Br)cc2O1,,CC(C)=O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040023938A1,CCc1ccc(S(=O)(=O)Cl)cc1.Nc1ccc(Cl)cc1>>CCc1ccc(S(=O)(=O)Nc2ccc(Cl)cc2)cc1,,c1ccncc1,,O,,test
US04146721,CCOC(=O)Cc1c(C)nn(-c2ccc(C)cc2)c1C>>Cc1ccc(-n2nc(C)c(CC(=O)O)c2C)cc1,,CCO,O,[K+].[OH-],,test
US05958968,CN(C)C=O.COc1cc2c(cc1Br)OCC2>>COc1cc2c(cc1C=O)OCC2,,C1CCOC1,,[Li]CCCC,,test
US20020193596A1,COC(=O)[C@H](CCSC)NC(=O)c1ccc(CNc2cccnc2)cc1-c1ccccc1>>CSCC[C@H](NC(=O)c1ccc(CNc2cccnc2)cc1-c1ccccc1)C(=O)O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US06248739B1,Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(C#CCO)ccc21>>Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CCCO)ccc21,[Pt],C1CCOC1,CO,[H][H],,test
US06166004,CC(C)(C)OC(=O)NN(Cc1ccc(-c2cncs2)cc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)C(F)(F)F>>CC(C)(C)OC(=O)NN(Cc1ccc(-c2cncs2)cc1)C[C@H](O)[C@@H](N)Cc1ccccc1,,CO,,ClCCl,O,test
US20020091135A1,CCOC(=O)c1cnc(Br)s1.OB(O)c1ccccc1F>>CCOC(=O)c1cnc(-c2ccccc2F)s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US20100260778A1,COC(=O)Cc1ccsc1-c1ccccc1.O=C(Cl)c1ccc(Cl)cc1>>COC(=O)Cc1cc(C(=O)c2ccc(Cl)cc2)sc1-c1ccccc1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20160207930A1,C=CCC1(CC=C)C[C@H]2[C@H](c3ccccc3OC)NCCN2C1=O.CN[C@H](C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>C=CCC1(CC=C)C[C@H]2[C@H](c3ccccc3OC)N(C(=O)N(C)[C@H](C)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CCN2C1=O,CN(C)c1ccncc1,CCOC(C)=O,,,,test
US04916121,CCCCCCCCCCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCCCCCCCCCC.Cc1cn(COCCO)c(=O)[nH]c1=O>>CCCCCCCCCCCCCCCCCCCC(=O)OCCOCn1cc(C)c(=O)[nH]c1=O,,c1ccncc1,,Cl,,test
US20040259912A1,COC(=O)c1cc([N+](=O)[O-])ccc1OC(c1ccccc1)c1ccc(Cl)cc1>>COC(=O)c1cc(N)ccc1OC(c1ccccc1)c1ccc(Cl)cc1,[Fe],CCO,O,[Ca+2].[Cl-].[Cl-],,test
US20130085161A1,CC(=O)Cl.Cc1ccc(N)c(N2CCC(NC(=O)OC(C)(C)C)CC2)c1>>CC(=O)Nc1ccc(C)cc1N1CCC(NC(=O)OC(C)(C)C)CC1,,CCOC(C)=O,,CCN(CC)CC,,test
US05093364,C=CCBr.O=c1[nH]c2cc(F)ccc2c(=O)o1>>C=CCNc1cc(F)ccc1C(=O)O,,CN(C)C=O,,O,[H-].[Na+],test
US20090149437A1,CC(C)(C)[Si](C)(C)Cl.O=C1c2ccccc2C(=O)N1CCCO>>CC(C)(C)[Si](C)(C)OCCCN1C(=O)c2ccccc2C1=O,,CN(C)C=O,,c1c[nH]cn1,,test
US20120208850A1,CC(C)(COS(=O)(=O)CCCS(=O)(=O)Oc1ccccc1)[C@@H](OCc1ccccc1)C(=O)O.CN(C)C=O.ClCCl>>CCOC(=O)[C@H](OCc1ccccc1)C(C)(C)COS(=O)(=O)CCCS(=O)(=O)Oc1ccccc1,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20060004012A1,CCOC(=O)CC(c1ccc(OCc2cccc(-c3ccc(C(F)(F)F)cc3)c2)cc1)c1ccno1>>O=C(O)CC(c1ccc(OCc2cccc(-c3ccc(C(F)(F)F)cc3)c2)cc1)c1ccno1,,CC(=O)O,,Cl,O,test
US20050070583A1,CCOC(=O)COc1ccc(S)cc1C(F)(F)F.Cc1ccsc1C(=CCO)c1sccc1C>>CCOC(=O)COc1ccc(SCC=C(c2sccc2C)c2sccc2C)cc1C(F)(F)F,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080076745A1,CC(C)(C)OC(=O)N[C@@H](CCCNC(=O)OCc1ccccc1)C(=O)NCCC[C@@H](CC(=O)NCCNC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1.Cl>>Cl.N[C@@H](CCCN(Cc1ccccc1)C(=O)O)C(=O)NCCC[C@@H](CC(=O)NCCNC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1,,C1COCCO1,,,,test
US20150284394A1,CC(C)(C)OC1CNC1.CN(C)CCn1cc(-c2cc3c(-c4ccc(CN)c(F)c4)ncnc3[nH]2)cn1.O=C(n1ccnc1)n1ccnc1>>CN(C)CCn1cc(-c2cc3c(-c4ccc(CNC(=O)N5CC(OC(C)(C)C)C5)c(F)c4)ncnc3[nH]2)cn1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US05523302,C1CO1.CC(=O)O.COC(=O)c1cccc(N)c1>>COC(=O)c1cccc(N(CCO)CCO)c1,,O,,,,test
US20110152253A1,C=CC1(O)CCOc2ccccc21.NC(N)=S>>N=C(N)SC/C=C1\CCOc2ccccc21,,CC(=O)O,,,,test
US20120289504A1,CC(C)(C)OC(=O)N1CCO[C@H](COS(C)(=O)=O)C1.O=C1NC(=O)c2ccccc21>>CC(C)(C)OC(=O)N1CCO[C@H](CN2C(=O)c3ccccc3C2=O)C1,,CN(C)C=O,,O,[K],test
US04709044,Cc1[nH]c(=O)[nH]c1C(=O)CCCCC(=O)O>>CC1NC(=O)NC1CCCCCC(=O)O,O=[Pt]=O,CC(=O)O,,[H][H],,test
US20110136843A1,C[C@@]1(COS(=O)(=O)c2cccc([N+](=O)[O-])c2)CO1.OCc1ccc(F)cc1O>>C[C@@]1(COc2cc(F)ccc2CO)CO1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070032481A1,CCOC(C)=O.CS(=O)(=O)Cl.Cc1ccc(-c2cc(CCN=[N+]=[N-])nc(Cc3ccccc3)n2)cc1>>Cc1ccc(-c2cc(CCOS(C)(=O)=O)nc(Cc3ccccc3)n2)cc1,,C1CCOC1,,CCN(CC)CC,,test
US05962496,CC(C)(C)OC(=O)N1CC(=Cc2c(C(=O)O)[nH]c3cc(Cl)cc(Cl)c23)C(=O)N1c1ccc(N)cc1.C[Si](C)(C)N=C=O>>CC(C)(C)OC(=O)N1CC(=Cc2c(C(=O)O)[nH]c3cc(Cl)cc(Cl)c23)C(=O)N1c1ccc(NC(N)=O)cc1,,C1CCOC1,,,,test
US06657052B1,COc1cc(C(C)Oc2c(C)cc(C=O)cc2C)c([N+](=O)[O-])cc1OC>>COc1cc(C(C)Oc2c(C)cc(CO)cc2C)c([N+](=O)[O-])cc1OC,,CCO,,[BH4-].[Na+],,test
US20050148623A1,COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(-c2cccnc2)cc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(C)(C)C>>COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(-c2cccnc2)cc1)C[C@H](O)[C@@H](N)Cc1ccccc1)C(C)(C)C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020147334A1,CC(O)c1cccc(N(C)C(=O)OC(C)(C)C)n1.CCOC(=O)CN(Cc1ccccc1)Cc1ccc(O)cc1>>CCOC(=O)CN(Cc1ccccc1)Cc1ccc(OCCc2cccc(N(C)C(=O)OC(C)(C)C)n2)cc1,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04992588,CC(=O)OC(C)=O.COCc1ccccc1CN>>COCc1ccccc1CNC(C)=O,,Cc1ccccc1,,[Na+].[OH-],,test
US20100286140A1,COC(=O)c1ccc(Nc2nn3c(-c4ccc(OC)cc4)nnc3c3ccccc23)cc1>>COc1ccc(-c2nnc3c4ccccc4c(Nc4ccc(C(=O)O)cc4)nn23)cc1,,CO,,O,[K+].[OH-],test
US20130237515A1,BrP(Br)Br.Cc1cc(CO)ccc1C(=O)Cn1ccc(OCc2ccccc2)cc1=O>>Cc1cc(CBr)ccc1C(=O)Cn1ccc(OCc2ccccc2)cc1=O,,ClCCl,,,,test
US20120322831A1,COC(=O)C(N)(CC(C)C)C(=O)c1cccnc1>>CC(C)CC(N)(C(=O)O)C(=O)c1cccnc1,,CO,O,C1CCOC1,[Li+].[OH-],test
US20140018319A1,CSc1nc(SC)c2nccn2n1.O=C1CCC(=O)N1Br>>CSc1nc(SC)c2ncc(Br)n2n1,,CN(C)C=O,O,,,test
US05846537,NCCCCCC(=O)O.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(O)CCCCCNC(=O)C(F)(F)F,,O,,,,test
US20120114739A1,COC(=O)C1CCN(c2cc(N)n3ncc(-c4cnc5ccccc5c4)c3n2)C1>>Nc1cc(N2CCC(C(=O)O)C2)nc2c(-c3cnc4ccccc4c3)cnn12,,O,,C1CCOC1,[Li+].[OH-],test
US05153316,C#CCBr.N#Cc1c2n(c(=O)n1-c1cc(O)c(Cl)cc1F)CCCC2>>C#CCOc1cc(-n2c(C#N)c3n(c2=O)CCCC3)c(F)cc1Cl,,Cc1ccccc1,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20130303492A1,NC(=O)c1c(Nc2ccc([N+](=O)[O-])cc2)n[nH]c1NCc1ccc(O)cc1>>NC(=O)c1c(Nc2ccc(N)cc2)n[nH]c1NCc1ccc(O)cc1,[Pd],CO,,,,test
US20090042897A1,CCOC(=O)C1CCC2(CC1)CO2.Nc1ccccc1>>CCOC(=O)C1CCC(O)(CNc2ccccc2)CC1,,CC(C)(C)O,,[Cl-].[NH4+],,test
US20070254866A1,CC(C)I.CCOC(=O)c1cn(C2CC2)c2c(O)c(F)c(F)c([N+](=O)[O-])c2c1=O>>CCOC(=O)c1cn(C2CC2)c2c(OC(C)C)c(F)c(F)c([N+](=O)[O-])c2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110034464A1,COC(=O)Nc1ccc(Cl)cc1CN.Cl.N#CC(C(N)=O)C1OC(=O)C(Cl)=C1Cl>>CN(C(=O)O)c1ccc(Cl)cc1Cn1cc(Cl)cc(C(N)=O)c1=N.Cl,,CCO,,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2F)c(=O)n(C2CCOC(C)(C)C2)c2nc(C)nn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2F)c(=O)n(C2CCOC(C)(C)C2)c2nc(C)nn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20060178418A1,CC(C)Oc1ccc(C(N)=O)c2c1oc1ccccc12.O=C(OO)c1cccc(Cl)c1>>CC(C)Oc1ccc(C(=O)[NH2+][O-])c2c1oc1ccccc12,,ClC(Cl)Cl,,,,test
US20130011361A1,COC(=O)c1cc([N+](=O)[O-])n[nH]1.COc1ccc(CBr)cc1>>COC(=O)c1cc([N+](=O)[O-])nn1Cc1ccc(OC)cc1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20140221393A1,COc1ccc(N2CCN(c3ccc(-n4cnn(C5CCCCC5)c4=O)cc3)CC2)cc1>>O=c1n(-c2ccc(N3CCN(c4ccc(O)cc4)CC3)cc2)cnn1C1CCCCC1,,Br,,,,test
US20040047960A1,CCCC(C)(CC(=O)OCC)SCc1ccccc1>>CCCC(C)(CCO)SCc1ccccc1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],[Cl-].[NH4+],test
US20140288123A1,CC(Oc1ccccc1)c1ccc(C(=O)O)cc1Cl.Cc1cc(C)c(CN)c(O)n1>>Cc1cc(C)c(CNC(=O)c2ccc(C(C)Oc3ccccc3)c(Cl)c2)c(O)n1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US05202356,CCOC(=O)C=Cc1ccccc1>>OCC=Cc1ccccc1,,CCCCCC,ClCCl,CC(C)C[Al+]CC(C)C.[H-],,test
US20120108619A1,CC(C)n1cc(CBr)c(I)n1.CCOC(=O)C1CCN(C(=O)OC(C)(C)C)CC1>>CCOC(=O)C1(Cc2cn(C(C)C)nc2I)CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20060135551A1,CCOC(=O)N1c2c(cc(C)nc2C)C(=NO)CC1CC>>CCOC(=O)N1c2c(cc(C)nc2C)C(N)CC1CC,[Zn],CC(=O)O,,,,test
US20090023753A1,CCN=C=O.Nc1cc(CCl)ccn1>>CCNC(=O)Nc1cc(CCl)ccn1,,CCOC(C)=O,CN(C)C=O,,,test
US06051592,COC(=O)Cl.OC(Cc1ccccc1Cl)(Cn1ncnc1S)C1(Cl)CC1>>COC(=O)Sc1ncnn1CC(O)Cc1ccccc1Cl,,ClCCl,,CCN(CC)CC,,test
US20100298336A1,COc1ccc(CSc2nc(C)cc(O)n2)c(Cl)c1>>Cc1cc(O)nc(SCc2ccc(O)cc2Cl)n1,,ClCCl,,BrB(Br)Br,O,test
US20130079478A1,CC=Nc1c(C)cccc1C>>CCNc1c(C)cccc1C,,C1CCOC1,CO,O,[BH4-].[Na+],test
US20100137322A1,CCOC(=O)c1ccc(Cl)nc1.O=C(OO)c1cccc(Cl)c1.SC1CCCC1>>O=C(O)c1ccc(S(=O)(=O)C2CCCC2)nc1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20120289495A1,Cc1nc(-c2ccc(F)cc2)cs1.O=C1CCC(=O)N1Br>>Fc1ccc(-c2csc(CBr)n2)cc1,,ClC(Cl)(Cl)Cl,ClCCl,,,test
US20150291659A1,C[C@@H](NC(=O)CNC(=O)OC(C)(C)C)C(=O)Nc1ccccc1/C=C/CCCC(=O)OCC(Cl)(Cl)Cl>>C[C@H]1NC(=O)CNC(=O)CCCC=Cc2ccccc2NC1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040152742A1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(-c2ccc(Cl)cc2)cn1>>CCOC(=O)/C=C/c1ccc(-c2ccc(Cl)cc2)cn1,,C1CCOC1,,,,test
US20150094328A1,Fc1cccc(CBr)c1F.O=C(N[C@H]1CCCC[C@@H]1O)c1c[nH]c2c(Cl)ccnc12>>O=C(N[C@H]1CCCC[C@@H]1O)c1cn(Cc2cccc(F)c2F)c2c(Cl)ccnc12,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100009991A1,CCOC(=O)/C=C/c1cccc(/C=C/C(=O)O)c1>>CCOC(=O)CCc1cccc(CCC(=O)O)c1,[Pd],CCOC(C)=O,,C1CCOC1,,test
US20110034469A1,CCO[C@@H]1C[C@@H]2CN(C(=O)[C@@H](NC(=O)[C@H](C3CC3)N(C)C(=O)OC(C)(C)C)C3CCC(F)(F)CC3)[C@H](C(=O)N[C@@H]3CCOc4ccccc43)CN2C1>>CCO[C@@H]1C[C@@H]2CN(C(=O)[C@@H](NC(=O)[C@@H](NC)C3CC3)C3CCC(F)(F)CC3)[C@H](C(=O)N[C@@H]3CCOc4ccccc43)CN2C1,,O=C(O)C(F)(F)F,,,,test
US05270310,CCCCCCCCCCCCCCCC(=O)Cl.CN(C)CCCN>>CCCCCCCCCCCCCCCC(=O)NCCCN(C)C,,ClCCl,,,,test
US20150152069A1,CC(=O)N1CCNCC1.O=[N+]([O-])c1ccc(Cl)cc1Nc1ccccc1>>CC(=O)N1CCN(c2ccc([N+](=O)[O-])c(Nc3ccccc3)c2)CC1,,CS(C)=O,,O,,test
US06835731B2,CS(=O)(=O)OCc1ccc(CNC(=O)c2ccccn2)cc1.NC1CCCc2cccnc21>>O=C(NCc1ccc(CNC2CCCc3cccnc32)cc1)c1ccccn1,,O,,,,test
US20140080808A1,CSC1=NCCS[C@@](C)(CO[Si](C)(C)C(C)(C)C)C1.NNC(=O)C1(c2ccc(Br)cc2)CC1>>CC(C)(C)[Si](C)(C)OC[C@@]1(C)Cc2nnc(C3(c4ccc(Br)cc4)CC3)n2CCS1,,CCCCO,,,,test
US20150284395A1,CC(=O)N(C)C.Cn1ncc2cc(-c3cc(=O)n4ncc(C(N)=O)c4[nH]3)ccc21>>CC(=NC(=O)c1cnn2c(=O)cc(-c3ccc4c(cnn4C)c3)[nH]c12)N(C)C,,CN(C)C=O,,CC(=O)N(C)C,,test
US20070082890A1,COC(=O)Cc1nc(C)sc1C.NN>>Cc1nc(CC(=O)NN)c(C)s1,,CCCCO,,O,,test
US20090137577A1,C[C@@H]1CN(Cc2ccc(Cl)nc2)C(=O)O1.OB(O)c1ccc(Cl)cc1F>>C[C@@H]1CN(Cc2ccc(-c3ccc(Cl)cc3F)nc2)C(=O)O1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US03984467,CC(C)(C)CCC(=N)N.S=C=Nc1ccc(Cl)cc1>>CC(C)(C)CCC(=N)NC(=S)Nc1ccc(Cl)cc1,,CC(C)=O,,Cl,[Na],test
US20080234255A1,CCOC(=O)CCN(c1nc(Cl)ncc1N)C1CCCC1(C)C>>CC1(C)CCCC1N1CCC(=O)Nc2cnc(Cl)nc21,,CC(=O)O,,CCO,,test
US20140206875A1,CCCI.COC(=O)C(C)(C)NS(=O)(=O)c1ccccc1C(F)(F)F>>CCCN(C(C)(C)C(=O)OC)S(=O)(=O)c1ccccc1C(F)(F)F,,CN(C)C=O,,O,,test
US20100093711A1,CC1(C)C(=O)Nc2ccccc2C1=O.CI>>CN1C(=O)C(C)(C)C(=O)c2ccccc21,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US05166347,CC(C)OC(=NC#N)c1cccnc1.NC(c1ccccc1)c1ccccc1>>N#CNC(=NC(c1ccccc1)c1ccccc1)c1cccnc1,,CO,,,,test
US20120202856A1,CC(C)(C)C(N)=S.O=CC(Br)C=O>>CC(C)(C)c1ncc(C=O)s1,,CCO,,,,test
US20160024059A1,CI.Cc1cc(O)cc(Br)c1>>COc1cc(C)cc(Br)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150150893A1,C=C1CCC2C3(C)COC(C)(C)OC3CCC2(C)C1C/C=C1/C(=O)OCC1O.O=C(OO)c1cccc(Cl)c1>>CC1(C)OCC2(C)C(CCC3(C)C(C/C=C4/C(=O)OCC4O)C4(CCC23)CO4)O1,,ClC(Cl)Cl,,,,test
US20030134849A1,CCCS(=O)(=O)Cl.CCc1ccc(-c2ccc([C@@]3(CC(=O)OC(C)(C)C)CCNCCS3(=O)=O)s2)cc1>>CCCS(=O)(=O)N1CC[C@](CC(=O)OC(C)(C)C)(c2ccc(-c3ccc(CC)cc3)s2)S(=O)(=O)CC1,,CCOC(C)=O,ClC(Cl)Cl,c1ccncc1,,test
US20140121200A1,CC(C)(C)OC(=O)N1CCC(O[Si](C)(C)C(C)(C)C)C(CN=[N+]=[N-])C1>>CC(C)(C)OC(=O)N1CCC(O[Si](C)(C)C(C)(C)C)C(CN)C1,[Pd],,,,,test
US20070032494A1,COC(=O)c1cc(Br)c(C)c(Br)c1.NC(=O)CCC(=O)NBr>>COC(=O)c1cc(Br)c(CBr)c(Br)c1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20040002461A1,CC1(C)CC(OC(=O)C2CC2)CC(C)(C)N1O.Cl>>CC1(C)CC(OC(=O)C2CC2)CC(C)(C)N1O.Cl,,CCO,,,,test
US20070093548A1,CCC(C)c1c(OC)cccc1OC>>CCC(C)c1c(O)cccc1OC,,ClCCl,,BrB(Br)Br,,test
US20150158851A1,CS(=O)(=O)CCC(c1ccccc1)n1cc([N+](=O)[O-])cn1>>CS(=O)(=O)CCC(c1ccccc1)n1cc(N)cn1,[Ni],CO,,,,test
US20160185785A1,COC1CN(C(=O)OC(C)(C)C)CCC1=O.C[S+](C)(C)=O>>COC1CN(C(=O)OC(C)(C)C)CCC12CO2,,CS(C)=O,,[H-].[Na+],,test
US20050261272A1,C#C[Si](C)(C)C.CC(C)NC(C)C.CCOC(=O)c1cc2cc(Br)ncc2[nH]1>>CCCC(C)C.CCOC(C)=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,,,test
US20060004043A1,CCOC(=O)CN1CCCCC1C.NN>>CC1CCCCN1CC(=O)NN,,CCO,,,,test
US20080312226A1,Fc1ccc(-c2csc(N3CCNCC3)n2)cc1.O=C(Nc1cnccn1)OCC(Cl)(Cl)Cl>>O=C(Nc1cnccn1)N1CCN(c2nc(-c3ccc(F)cc3)cs2)CC1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20060247260A1,Brc1cnc(OCc2ccccc2)nc1.COC(=O)C(Cc1ccccc1)NC(=O)c1ccc(B(O)O)cc1>>COC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1-c1cnc(OCc2ccccc2)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US03969363,CC(=O)CC(=O)c1ccc(C)nc1.Cl.O=S(Cl)Cl>>Cc1ccc(C(O)CC(C)Cl)cn1.Cl,,Cc1ccccc1,,[Na],,test
US20160152621A1,COc1cc([N+](=O)[O-])ccc1-c1ccnnc1>>COc1cc(N)ccc1-c1ccnnc1,[Pd],CCO,,,,test
US20150011540A1,Cc1noc(C)c1-c1ccc2cnn3c2c1OCC3c1ccccc1.O=C1CCC(=O)N1Br>>Cc1noc(C)c1-c1cc(Br)c2cnn3c2c1OCC3c1ccccc1,,CC#N,CCOC(C)=O,,,test
US20100298339A1,COc1ccc(-c2cccc3nc(Nc4ccc(OCCCN5C(=O)c6ccccc6C5=O)cc4)nn23)cc1>>COc1ccc(-c2cccc3nc(Nc4ccc(OCCCN)cc4)nn23)cc1,,CCO,,NN,O,test
US20100204196A1,C1CCNC1.Cc1ccc(NC(=O)CCl)cc1[N+](=O)[O-]>>Cc1ccc(NC(=O)CN2CCCC2)cc1[N+](=O)[O-],,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20090312383A1,CC(=O)OC(C)=O.CCCC(O)(CCC)c1cccc2nc(Nc3c(C)cc(Cl)cc3OC)n(CCO)c12>>CCCC(O)(CCC)c1cccc2nc(Nc3c(C)cc(Cl)cc3OC)n(CCOC(C)=O)c12,,c1ccncc1,,,,test
US05929120,CCOC(=O)[C@H](CNC(=O)c1ccc(C#Cc2nc(N)cc3ccccc23)cc1)NS(=O)(=O)c1ccccc1.O=C(O)C(F)(F)F>>Nc1cc2ccccc2c(C#Cc2ccc(C(=O)NC[C@H](NS(=O)(=O)c3ccccc3)C(=O)O)cc2)n1.O=C(O)C(F)(F)F,,C1COCCO1,Cl,CC#N,O,test
US05831115,NCc1ccccc1.O=Cc1ccc(Oc2ccccc2)cc1>>c1ccc(CNCc2ccc(Oc3ccccc3)cc2)cc1,[Pd],CCO,CCOCC,[H][H],,test
US20080293802A1,CC(C)(C)OC(=O)c1cccc2c1N(C(=O)OC(C)(C)C)CC2.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)c1cc(Br)cc2c1N(C(=O)OC(C)(C)C)CC2,,ClCCl,,O,,test
US20080221086A1,N#CO[K].NCCCn1ccnc1.O=Cc1ccccc1F.[C-]#[N+]CCc1c[nH]c2ccccc12>>O=C1NC(=NCCc2c[nH]c3ccccc23)C(c2ccccc2F)N1CCCn1ccnc1,,CO,,Cl,c1ccncc1,test
US20130064770A1,Cn1c(=O)cnn(CCCCCl)c1=O.Fc1cccc(N2CCNCC2)n1>>Cn1c(=O)cnn(CCCCN2CCN(c3cccc(F)n3)CC2)c1=O,,CCCCO,,CCN(CC)CC,,test
US20130165423A1,CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)O.C[C@@H]1CN(c2ccc3cnn([C@H](C)c4ccc(Cl)cc4Cl)c3c2)CCN1>>C[C@@H]1CN(c2ccc3cnn([C@H](C)c4ccc(Cl)cc4Cl)c3c2)CCN1C(=O)[C@H]1CCCN1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100016303A1,Cc1cc(C)n2cc(CCl)nc2n1.Cn1cc(-c2ccccc2)[nH]c1=S>>Cc1cc(C)n2cc(CSc3nc(-c4ccccc4)cn3C)nc2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130245021A1,CCOc1ccccc1CCN.Fc1ccc2ncc(Br)n2n1>>CCOc1ccccc1CCNc1ccc2ncc(Br)n2n1,,CC(C)O,,CCN(CC)CC,,test
US20010016570A1,CC(C)(C)OC(=O)N[C@H](CO)C(=O)O.Fc1ccc(CBr)c(F)c1>>CC(C)(C)OC(=O)NC(COCc1ccc(F)cc1F)C(=O)O,,C1CCOC1,CN(C)C=O,CC(C)(C)[O-].[K+],,test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1Cl.OB(O)c1cccc2ncccc12>>CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1-c1cccc2ncccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,CCN(C(C)C)C(C)C,,test
US20140179670A1,Cc1c(-c2cccnc2Br)c(=O)n(C(C)C)c(=O)n1-c1cccc(C(F)(F)F)c1.N#Cc1ccc(B(O)O)cc1>>Cc1c(-c2cccnc2-c2ccc(C#N)cc2)c(=O)n(C(C)C)c(=O)n1-c1cccc(C(F)(F)F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20050222146A1,CC(C)(C)OC(=O)N[C@@]1(C(=O)O)C[C@@H]1c1ccccc1>>N[C@@]1(C(=O)O)C[C@@H]1c1ccccc1,,CCOCC,,C1COCCO1,Cl,test
US20090062282A1,CC(=O)OCCBr.Cn1c(N)nc(CCc2cccc(-c3cccc(O)c3)c2)cc1=O>>CC(=O)OCCOc1cccc(-c2cccc(CCc3cc(=O)n(C)c(N)n3)c2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04656298,CCOC(OCC)P([O-])OCC.N#CC=Cc1ccc(Cl)cc1>>CCOC(OCC)P(=O)(OCC)C(CC#N)c1ccc(Cl)cc1,,CCO,,CC(=O)O,[H-].[Na+],test
US20150166483A1,CNC(=O)c1cc(C(C)(C)C)cc(NC(=O)Oc2ccccc2)c1OC.COCCOCCOCCOc1cc(Nc2cc(Oc3ccc(N)c4ccccc34)ccn2)cc(OC)c1>>CNC(=O)c1cc(C(C)(C)C)cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(OC)cc(OCCOCCOCCOC)c4)c3)c3ccccc23)c1OC,,C1CCOC1,,CCN(CC)CC,,test
US20080021217A1,CC(NC(=O)c1cccs1)C(=O)NN.N#Cc1ccncc1>>CC(NC(=O)c1cccs1)c1nc(-c2ccncc2)n[nH]1,,CCCCO,,O=C([O-])[O-].[K+].[K+],,test
US20110077290A1,COC(=O)c1ccc(N=C=S)cc1[N+](=O)[O-].NN>>COC(=O)c1ccc(NC(=S)NN)cc1[N+](=O)[O-],,C1CCOC1,,O,O,test
US20120323007A1,CC(C)(CO)NC(=O)c1cccc(N)n1.O=S(Cl)Cl>>CC(C)(CCl)NC(=O)c1cccc(N)n1,,ClC(Cl)Cl,,,,test
US04188395,CCOC(=O)/C=C(/C)N.CCOC(=O)CC(=O)COC(C)=O.O=Cc1ccccn1>>CCOC(=O)C1=C(C)NC(COC(C)=O)=C(C(=O)OCC)C1c1ccccn1,,CCO,,,,test
US20120172351A1,C1CCNC1.Cc1cc(C)nc(Cl)n1>>Cc1cc(C)nc(N2CCCC2)n1,,CCO,O,CCN(CC)CC,,test
US20160257673A1,Fc1ccc(-c2ccc3nc(Cl)nc(Cl)c3c2)cc1.NC1CC1>>Fc1ccc(-c2ccc3nc(Cl)nc(NC4CC4)c3c2)cc1,,C1COCCO1,CCOC(C)=O,,,test
US06399582B1,O=C1c2ccccc2C(=O)N1C/C=C/Cn1cnc2ncccc21>>NCC=CCn1cnc2ncccc21,,CCO,,NN,O,test
US20100298321A1,COC(=O)c1ccc(N2CCN(CC3=C(c4ccc(Cl)cc4)CC(C)(C)CC3)CC2)cc1Oc1cccc2[nH]ncc12.O=C1CCC(=O)N1Cl>>COC(=O)c1cc(Cl)c(N2CCN(CC3=C(c4ccc(Cl)cc4)CC(C)(C)CC3)CC2)cc1Oc1cccc2[nH]ncc12,,CC#N,,,,test
US20110015392A1,Cc1oc(=O)c(Cl)nc1Cl.Nc1ccc([N+](=O)[O-])cc1>>Cc1oc(=O)c(Nc2ccc([N+](=O)[O-])cc2)nc1Cl,,C1CCOC1,,O,,test
US20100022522A1,CCC(CCO)n1cc(-c2ncnc3c2ccn3COCC[Si](C)(C)C)cn1.COC(=O)Cl>>CCC(CCOC(=O)OC)n1cc(-c2ncnc3c2ccn3COCC[Si](C)(C)C)cn1,,O,,c1ccncc1,,test
US04181806,C=O.CNC1CCS(=O)(=O)C1.OP(O)O>>CN(CP(=O)(O)O)C1CCS(=O)(=O)C1,,CCO,,Cl,O,test
US04769402,CC1(C)CC(=O)OC1=O.Nc1ccc(O)cc1>>CC1(C)CC(=O)N(c2ccc(O)cc2)C1=O,,CN(C)C=O,,,,test
US20140288081A1,COC(=O)c1ccc([N+](=O)[O-])cc1Cl.N#C[Cu]>>COC(=O)c1ccc([N+](=O)[O-])cc1C#N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US06936602B1,CCCOCCOc1ccc(OB([O-])[O-])cc1.COC(=O)C1=Cc2cc(Br)ccc2N(Cc2ccccc2)CC1>>CCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3Cc2ccccc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[K+].[K+],test
US20120046306A1,O=C1Cc2ncc(Cl)cc2N1.O=Cc1cccc(Br)c1F>>O=C1Nc2cc(Cl)cnc2/C1=C/c1cccc(Br)c1F,,CO,,C1CCNCC1,,test
US20160002177A1,COCCOCOc1cc(-c2ccccc2COCCC2CCN(CC(F)(F)F)CC2)c(Cl)c2c(=O)n(COCCOC)cnc12.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=c1[nH]cnc2c(O)cc(-c3ccccc3COCCC3CCN(CC(F)(F)F)CC3)c(Cl)c12,,O,,,,test
US20130116430A1,CCCCOC(=O)C=Cc1cc([N+](=O)[O-])cnc1NC>>Cn1c(=O)ccc2cc([N+](=O)[O-])cnc21,,O,,CO,C[O-].[Na+],test
US04695576,O=C(O)[C@@H]1CCCCN1>>O=C(O)C1CCCCN1,,O,,,,test
US20050203139A1,C=CC(=O)Cl.COC(=O)c1cc(Cl)c(N)cc1O>>C=CC(=O)Nc1cc(O)c(C(=O)OC)cc1Cl,,CCN(CC)CC,,ClCCl,,test
US20090088431A1,FC(F)(F)c1ccccc1OC1CCN(c2ccc(Cl)nn2)CC1.O>>Oc1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1,,CC(=O)O,O,CC(=O)[O-].[K+],,test
US04840965,Oc1ccc(OCc2ccccc2)c2c1OCO2>>O=C1C=CC(=O)C2=C1OCO2,[Pd],C1CCOC1,,,,test
US06420560B1,Clc1ccc(C(Cl)c2ccccc2)cc1.Clc1ccc(C(c2ccccc2)N2CCNCC2)cc1>>Clc1ccc(C(c2ccccc2)N2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)cc1,,CCN(CC)CC,ClCCl,O=C([O-])[O-].[Na+].[Na+],,test
US20150299203A1,Cc1cc(-c2cnn3c(NCC4CCOCC4)nc(S(C)(=O)=O)nc23)ccc1C(=O)NC1CC1.NC1CCCC1>>Cc1cc(-c2cnn3c(NCC4CCOCC4)nc(NC4CCCC4)nc23)ccc1C(=O)NC1CC1,,C1CCOC1,,,,test
US20090023725A1,CCNC(=O)c1cc(F)c(C)c(-c2ccc3c(-c4ccccn4)n[nH]c3c2)c1.O=C(OO)c1cccc(Cl)c1>>CCNC(=O)c1cc(F)c(C)c(-c2ccc3c(-c4cccc[n+]4[O-])n[nH]c3c2)c1,,ClC(Cl)Cl,,CO,,test
US20040121989A1,CC(=O)OC(C)=O.CCCCc1nc(CN)nn1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1>>CCCCc1nc(CNC(C)=O)nn1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,O,,O=C([O-])[O-].[K+].[K+],,test
US05185446,CC(C)(C)OC(=O)NC1CCc2[nH]c(=O)n3cc(-c4ccccc4F)nc3c2C1>>NC1CCc2[nH]c(=O)n3cc(-c4ccccc4F)nc3c2C1,,O=C(O)C(F)(F)F,,,,test
US05256679,CNC(=N[N+](=O)[O-])SC.O=C(Cl)Cc1ccccc1>>CSC(=N[N+](=O)[O-])N(C)C(=O)Cc1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100004238A1,CC#N.O=Cc1c(O)cccc1Oc1ccc([N+](=O)[O-])cc1Cl>>O=[N+]([O-])c1ccc(Oc2cccc3oncc23)c(Cl)c1,,O,,O=C([O-])O.[Na+],,test
US20030073700A1,Brc1cccc2cc[nH]c12.CC(C)(C)OC(=O)N1CCC(=O)CC1>>CC(C)(C)OC(=O)N1CCC(O)(c2cccc3cc[nH]c23)CC1,,C1CCOC1,,[Li]CCCC,,test
US20080269192A1,C[C@@H](CNC(=O)OC(C)(C)C)n1c(CCl)nc2cnc3ccccc3c21>>C[C@H]1CNCc2nc3cnc4ccccc4c3n21,,CCO,Cl,ClC(Cl)Cl,,test
US20150018335A1,Cc1cc(B(O)O)cc(C)n1.Cc1cc(Br)ccc1CN1CCN(C(=O)OC(C)(C)C)CC1>>Cc1cc(-c2ccc(CN3CCN(C(=O)OC(C)(C)C)CC3)c(C)c2)cc(C)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20100010053A1,N#Cc1ccc2cc[nH]c2c1.NO>>N=C(NO)c1ccc2cc[nH]c2c1,,CCO,,Cl,O=C([O-])O.[Na+],test
US20140162876A1,CCC(O)(Cn1cncn1)c1ccc(Oc2ccc(Cl)cc2)cc1Cl.CCI>>CCOC(CC)(Cn1cncn1)c1ccc(Oc2ccc(Cl)cc2)cc1Cl,,C1CCOC1,,[H-].[Na+],,test
US20070185104A1,N#CCCNCCO.O=C(Cl)CCl>>N#CCCN(CCO)C(=O)CCl,,ClCCl,,,,test
US20150376136A1,Cc1ccc(S(=O)(=O)n2cccc2C(=O)CN(C)C(=O)[C@@H](C)C2CCCCC2)cc1>>C[C@H](C(=O)N(C)CC(=O)c1ccc[nH]1)C1CCCCC1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US04611056,COCCl.Oc1cc2c(c3ccccc13)Nc1ccccc1S2>>COCOc1cc2c(c3ccccc13)Nc1ccccc1S2,,C1CCOC1,O,CCOCC,[H-].[Na+],test
US20140194406A1,COc1ccc([N+](=O)[O-])cc1I>>COc1ccc(N)cc1I,[Fe],CO,O,[Cl-].[NH4+],,test
US06124341,CCc1cccc(CC)c1N.O=[N+]([O-])O>>CCc1cc([N+](=O)[O-])cc(CC)c1N,,O=S(=O)(O)O,,,,test
US20040019023A1,CC(C)(C)OC(=O)CBr.C[C@H](O)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@@]21C>>C[C@H](OCC(=O)OC(C)(C)C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@@]21C,,C1CCOC1,,C1COCCOCCOCCOCCO1,[H-].[Na+],test
US20040267007A1,N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O.O=C(Cl)OCC(Cl)(Cl)Cl>>O=C[C@H](NC(=O)OCC(Cl)(Cl)Cl)[C@@H](O)[C@H](O)[C@H](O)CO,,O,,Cl,O=C([O-])O.[Na+],test
US20070135442A1,C/C(N)=N\OC(=O)c1ccc([N+](=O)[O-])cc1>>Cc1noc(-c2ccc([N+](=O)[O-])cc2)n1,,CC#N,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20150307494A1,COc1ccc(B2OC(C)(C)C(C)(C)O2)c(C)c1.Cc1ncnc(C)c1Br>>COc1ccc(-c2c(C)ncnc2C)c(C)c1,,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140235895A1,C=O.CCCCCCCCc1ccc(CCC[N+](=O)[O-])cc1.CO>>CCCCCCCCc1ccc(CCC(CO)(CO)[N+](=O)[O-])cc1,,CCOC(C)=O,O,CCN(CC)CC,,test
US20030092677A1,CC(C)(C)OC(=O)Nc1ccc(-c2ccco2)cc1NC(=O)CC(=O)c1cccc(C#N)c1>>N#Cc1cccc(C2=Nc3ccc(-c4ccco4)cc3NC(=O)C2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050209290A1,C=CCOc1ccc(CO)c(F)c1.O=S(Cl)Cl>>C=CCOc1ccc(CCl)c(F)c1,,CN(C)C=O,ClCCl,,,test
US20060183736A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CS(=O)(=O)c1ccc(Br)cc1F>>CC1(C)OB(c2ccc(S(C)(=O)=O)c(F)c2)OC1(C)C,,CCOC(C)=O,CS(C)=O,ClCCl,CC(=O)[O-].[K+],test
US20060258689A1,Clc1ncnc2c1CN(Cc1ccccc1)CC2.Nc1ccc(F)cc1>>Fc1ccc(Nc2ncnc3c2CN(Cc2ccccc2)CC3)cc1,,CC#N,,,,test
US05817688,N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(C=O)c1SC(F)(F)F.[Li]C>>CC(O)c1c(SC(F)(F)F)c(C#N)nn1-c1c(Cl)cc(C(F)(F)F)cc1Cl,[Cu]I,CCOCC,,Cl,,test
US20140128255A1,CCC(=O)c1ccc(Oc2ccc(Cl)cc2)cc1Cl.C[S+](C)C>>CCC1(c2ccc(Oc3ccc(Cl)cc3)cc2Cl)CO1,,C1CCOC1,CS(C)=O,[H-].[Na+],,test
US04323691,CCOC(=O)C(C)Br.COc1ccc(C(=O)c2ccc(O)c(Cl)c2Cl)cc1>>CCOC(=O)C(C)Oc1ccc(C(=O)c2ccc(OC)cc2)c(Cl)c1Cl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030162799A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C=Cc1ccc(N)cc1>>CCOC(=O)/C=C/c1ccc(NC(=O)OC(C)(C)C)cc1,,C1CCOC1,,,,test
US20150057260A1,CCNN.O=Cc1c(Cl)cc(Cl)nc1Cl>>CCn1ncc2c(Cl)nc(Cl)cc21,,CCO,,CCN(CC)CC,,test
US20140275027A1,COc1ccc(F)cc1-c1c(F)cnc2[nH]c(C3=CC4CNCC4C3)cc12.CS(=O)(=O)Cl>>COc1ccc(F)cc1-c1c(F)cnc2[nH]c(C3=CC4CN(S(C)(=O)=O)CC4C3)cc12,,CN1CCCC1=O,,CCN(CC)CC,O,test
US20120108815A1,CCCN(C(=O)CN1CCN(C(=O)OC(C)(C)C)CC1)C1CCc2c(cccc2OC)C1>>CCCN(C(=O)CN1CCNCC1)C1CCc2c(cccc2OC)C1,,O=C(O)C(F)(F)F,,,,test
US20040063946A1,CC(=O)N(C)C.Cc1cccc(-c2nc(N)sc2-c2ccnc(NC(=O)OC(C)(C)C)n2)c1.O=C(Cl)Cc1ccccc1>>Cc1cccc(-c2nc(NC(=O)Cc3ccccc3)sc2-c2ccnc(NC(=O)Cc3ccccc3)n2)c1,,CC(=O)N(C)C,,O=C([O-])O.[Na+],,test
US20050107449A1,CCOC(=O)CC(=O)CCc1ccccc1.O=S(=O)(Cl)Cl>>CCOC(=O)C(Cl)C(=O)CCc1ccccc1,,ClCCl,,O,,test
US20160002175A1,CNc1cc(-c2cccc(C(=O)O)c2)nc(N)n1.Cc1ccc(N)cc1>>CNc1cc(-c2cccc(C(=O)Nc3ccc(C)cc3)c2)nc(N)n1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130082209A1,CN(C)C=O.Cc1cc(C(C)(C)C)ncc1C#N.N>>CC(C)(C)c1cc2ccnc(N)c2cn1,,CCO,O,C,O=C[O-].[NH4+],test
US20160229871A1,COC(=O)c1cccc(Cn2nc(-c3cccc(CCOS(C)(=O)=O)c3)ccc2=O)c1.Cc1cc([N+](=O)[O-])[nH]n1>>COC(=O)c1cccc(Cn2nc(-c3cccc(CCn4nc(C)cc4[N+](=O)[O-])c3)ccc2=O)c1,,CN(C)C=O,,[H-].[Na+],,test
US20120208819A1,CC(C)(C)OC(=O)NCc1ccc(-c2cn(S(=O)(=O)c3ccccc3)c3ncnc(N)c23)cc1>>NCc1ccc(-c2cn(S(=O)(=O)c3ccccc3)c3ncnc(N)c23)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150218086A1,CC(C)(C)OC(=O)C[C@@H](CI)NC(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(CO)cc1Br>>CC(C)(C)OC(=O)C[C@@H](Cc1cc(CO)ccc1[N+](=O)[O-])NC(=O)OC(C)(C)C,[Zn],,,Cc1ccccc1P(c1ccccc1C)c1ccccc1C,,test
US20110207728A1,COC(=O)c1cc(Br)c[nH]1.COc1ccc(C(=O)CBr)cc1>>COC(=O)c1cccn1CC(=O)c1ccc(OC)cc1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20090197908A1,CNCc1ccccc1.C[N+](C)=c1ccn(S(=O)(=O)[N-]C(=O)OC(C)(C)C)cc1>>CN(Cc1ccccc1)S(=O)(=O)NC(=O)OC(C)(C)C,,ClCCl,,,,test
US20100317659A1,N#Cc1cc(N)n[nH]1.O=C(c1ccc(F)cc1)c1nc(Cl)c2ccccc2n1>>N#Cc1cc(Nc2nc(C(=O)c3ccc(F)cc3)nc3ccccc23)n[nH]1,,CN(C)C=O,,CO,,test
US20100093694A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(OS(=O)(=O)C(F)(F)F)cc12.N#Cc1cccc(B(O)O)c1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cccc(C#N)c3)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US03933804,CC(=O)c1ccc(OCC=C(C)CBr)cc1.SCc1ccccc1>>CC(=O)c1ccc(OCC=C(C)CSCc2ccccc2)cc1,,CN(C)C=O,,[Na],,test
US20160185823A1,CC(C)(C)OC(=O)NCC[C@H](O)C(=O)O.O=C(Cl)c1c(F)cc(-c2ccccc2)cc1F>>CC(C)(C)OC(=O)NCC[C@H](OC(=O)c1c(F)cc(-c2ccccc2)cc1F)C(=O)O,,CC#N,ClCCl,,,test
US20120214803A1,O=C(c1ccc(F)c(F)c1)c1ccc2cccnc2c1[N+](=O)[O-]>>Nc1c(C(=O)c2ccc(F)c(F)c2)ccc2cccnc12,[Pd],C1CCOC1,,,,test
US05525619,COCCn1nc(-c2ccc(OCCCC(F)(F)F)cc2)oc1=O>>O=c1oc(-c2ccc(OCCCC(F)(F)F)cc2)nn1CCO,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20070269494A1,CCCCCCOC(=O)c1ccc(O)cc1O.O=C1CCC(=O)O1>>CCCCCCOC(=O)c1ccc(OC(=O)CCC(=O)O)cc1O,,ClCCl,,,,test
US20110312960A1,CN1CCNCC1.COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(CCl)nc2)cc(OC)c1>>COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(CN3CCN(C)CC3)nc2)cc(OC)c1,,CC#N,ClCCl,CCN(C(C)C)C(C)C,,test
US20060183734A1,CN1c2ccccc2CN(C(=O)C(F)(F)F)c2ccccc21>>CN1c2ccccc2CNc2ccccc21,,CCO,,[Na+].[OH-],,test
US20110034469A1,CON(C)C(=O)[C@@H]1CN2CCC[C@@H]2CN1C(=O)OC(C)(C)C.C[Mg]Cl>>CC(=O)[C@@H]1CN2CCC[C@@H]2CN1C(=O)OC(C)(C)C,,C1CCOC1,,[Cl-].[NH4+],,test
US20090221586A1,NC(=O)c1ccc(OCc2ccccc2)c(OCc2ccccc2)c1.O=C(CCl)CCl>>ClCc1coc(-c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)n1,,CCCO,,,,test
US20020042429A1,N[C@H]1CN2CCC1CC2.O=C(O)/C=C/C(=O)O.O=C(O)c1cnc(Sc2ccccc2)s1>>O=C(N[C@H]1CN2CCC1CC2)c1cnc(Sc2ccccc2)s1.O=C(O)/C=C/C(=O)O,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110207746A1,CC(C)C1c2nc[nH]c2CCN1C(=O)OCC(Cl)(Cl)Cl.CC1(CO)COC1>>CC(C)C1c2nc[nH]c2CCN1C(=O)OCC1(C)COC1,,C1CCOC1,,[H-].[Na+],,test
US04440941,CC(=O)Sc1c(C)cccc1C(=O)O.CC(C)(C)OC(=O)CNC1CCCC1>>CC(=O)Sc1c(C)cccc1C(=O)N(CC(=O)OC(C)(C)C)C1CCCC1,,ClCCl,,,,test
US20090197866A1,CCN(CC)C(=O)Nc1cn(C2CCCCO2)nc1-c1nc2cc(OCCCCN3CCCCC3)c(F)cc2[nH]1>>CCN(CC)C(=O)Nc1c[nH]nc1-c1nc2cc(OCCCCN3CCCCC3)c(F)cc2[nH]1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050153970A1,NO.O=C1CCc2cc(F)ccc2C1>>ON=C1CCc2cc(F)ccc2C1,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US06596461B1,C=O.CC(C)[N+](=O)[O-].CC(O)CN>>CC(O)CNCC(C)(C)[N+](=O)[O-],,CC(C)O,,,,test
US06462183B1,CC(=O)C1C(=O)CC(C)(C)CC1=O.CC(=O)OC[C@H]1O[C@H](O[C@@H]2[C@@H](COC(C)=O)O[C@@H](N)[C@H](OC(C)=O)[C@H]2OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O>>CC(=O)OC[C@H]1O[C@H](O[C@@H]2[C@@H](COC(C)=O)O[C@@H](NC(C)=C3C(=O)CC(C)(C)CC3=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O,,CO,,,,test
US20100075952A1,Cc1c(C=O)[nH]c2c1C(=O)N(CCN1CCCCC1)CCC2.O=C1Cc2cc(F)ccc2N1>>Cc1c(C=C2C(=O)Nc3ccc(F)cc32)[nH]c2c1C(=O)N(CCN1CCCCC1)CCC2,,CCO,,C1CCNCC1,,test
US04963561,CN(C)C=Cc1ccncc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CN(C)C=C(C(=O)C(F)(F)F)c1ccncc1,,ClCCl,,CCN(CC)CC,,test
US20140357637A1,CC1(C)C(=O)Nc2nc(-c3nn(Cc4ccccc4F)c4ncccc34)nc(N)c21.O>>CC1(C)C(=O)Nc2nc(-c3nn(Cc4ccccc4F)c4ncccc34)nc(O)c21,,O=C(O)C(F)(F)F,,O=N[O-].[Na+],,test
US20110218192A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C1NC(=O)C2(CC(c3ccccc3)Oc3ccc(Br)cc32)N1>>O=C1NC(=S)NC12CC(c1ccccc1)Oc1ccc(Br)cc12,,C1COCCO1,,,,test
US04846882,BrC(Br)(Br)Br.O=C1C2=C(CCCC2)C(=O)N1c1cc(CO)c(Cl)cc1F>>O=C1C2=C(CCCC2)C(=O)N1c1cc(CBr)c(Cl)cc1F,,CCOCC,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110294776A1,Brc1ccc2nc(Cc3ccccc3)sc2c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(c2ccc3nc(Cc4ccccc4)sc3c2)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20080200473A1,CI.Cc1ccc(-c2nc3ccc(C)cn3c2CNC(=O)c2ccc(N(C)C)cc2)cc1>>Cc1ccc(-c2nc3ccc(C)cn3c2CN(C)C(=O)c2ccc(N(C)C)cc2)cc1,,CN(C)C=O,,[Na+].[OH-],,test
US03931174,COC(=O)c1c(CSC)[n+]([O-])c2ccccc2[n+]1[O-].O=C(OO)c1cccc(Cl)c1>>COC(=O)c1c(CS(C)=O)[n+]([O-])c2ccccc2[n+]1[O-],,ClC(Cl)Cl,,CCOCC,,test
US05283241,COC(=O)Nc1ccccc1-c1ccc(CO)cc1.C[Si](C)(C)Br>>COC(=O)Nc1ccccc1-c1ccc(CBr)cc1,,ClCCl,,,,test
US20160108036A1,CCOC(=O)c1cn[nH]c1.Cc1cnn(Cc2ccc(CO)cc2)c1>>CCOC(=O)c1cnn(Cc2ccc(Cn3cc(C)cn3)cc2)c1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120295915A1,O=C(C1CC1)N1CC[C@@H](CNc2ccncc2[N+](=O)[O-])C1>>Nc1cnccc1NC[C@@H]1CCN(C(=O)C2CC2)C1,[Pd],CO,,,,test
US04634710,COc1cc(COC(C)=O)ncc1C>>COc1cc(CO)ncc1C,,CCO,,[Na+].[OH-],,test
US04983619,CN(C)C=CC(=O)c1ccc(C(C)(C)C)cc1.N=C(N)N>>CC(C)(C)c1ccc(-c2ccnc(N)n2)cc1,,CCO,,O=C(O)O,,test
US20100041635A1,COC(=O)c1ccc(-c2ccc(C(C)=O)o2)cc1>>CC(=O)c1ccc(-c2ccc(C(=O)O)cc2)o1,,CCO,,Cl,[Na+].[OH-],test
US20140213575A1,Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)OC(C)(C)C)c1nnc(C)n1-2.Cl>>Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(CC(=O)O)c1n[nH+]c(C)n1-2.Cl,,C1COCCO1,Cl,,,test
US20160207893A1,CC(C)(C)OC(=O)NCCS.CCOC(=O)c1nc(OC)ncc1I>>CCOC(=O)c1nc(OC)ncc1SCCNC(=O)OC(C)(C)C,[Cu]I,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US05654316,CNc1ccccc1.O=C1CC(c2ccccc2)CC(=O)O1>>O=C(O)CC(CC(=O)NCc1ccccc1)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US05401621,CC(=O)N(C)N.O=S(=O)(O)CCN=C=S.[Na]>>CC(=O)N(C)NC(=S)NCCS(=O)(=O)O.[Na],,O,,CO,,test
US20040058979A1,CCOC(=O)Cc1c(C)c2c(c([N+](=O)[O-])c1C)N(C(C)=O)CC2>>CCOC(=O)Cc1c(C)c(N)c2c(c1C)CCN2C(C)=O,[Pd],CCO,,,,test
US20120071685A1,CC1=CC2C(C1)CC2(CC(=O)OC(C)(C)C)C[N+](=O)[O-]>>CC1=CC2C(C1)CC2(CN)CC(=O)OC(C)(C)C,[Fe],CCO,O,[Cl-].[NH4+],,test
US20050221990A1,CC(=NNC(=O)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl)C(C)(C)C.CC(=O)Cl>>CC(=O)OC(=NN=C(C)C(C)(C)C)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl,,ClCCl,,CCN(CC)CC,,test
US20040229900A1,CCN=C=O.COc1ccc(OC(CCCN2CC3CNCC(C3)C2)c2ccc(C#N)cc2)cc1OC>>CCNC(=O)N1CC2CC(CN(CCCC(Oc3ccc(OC)c(OC)c3)c3ccc(C#N)cc3)C2)C1,,CC#N,ClC(Cl)Cl,,,test
US20090137576A1,CCOC(C)=O.O=c1ccc(Br)c[nH]1>>CC(C)Oc1ccc(Br)cn1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160151375A1,COC(=O)CC1CCC(O)CC1.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)CC1CCC(OS(=O)(=O)c2ccc(C)cc2)CC1,,ClCCl,,CN(C)c1ccccn1,,test
US20030207865A1,Cc1cc([N+](=O)[O-])ccc1N=C1SCCN1CC(=O)C(C)(C)C>>Cc1cc([N+](=O)[O-])ccc1N=C1SCCN1CC(O)C(C)(C)C,,CO,,[BH4-].[Na+],,test
US20100048562A1,N#Cc1ccc2c(c1)CSCC2O.O=C(c1cnc[nH]1)N1CCCC1>>N#Cc1ccc2c(c1)CSCC2n1cncc1C(=O)N1CCCC1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150038438A1,C=CCCCC(O[Si](C)(C)C(C)(C)C)c1ccc(N(C)C)cc1C=C>>CN(C)c1ccc2c(c1)C=CCCCC2O[Si](C)(C)C(C)(C)C,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,Cc1ccccc1,,,,test
US20040102459A1,COc1cccc(Cn2cnc3c(-c4ccco4)nc(N)nc32)c1>>Nc1nc(-c2ccco2)c2ncn(Cc3cccc(O)c3)c2n1,,ClCCl,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05547983,COC(=O)CBr.O=C(OCc1ccccc1)c1ccc2cc(-c3ccc(O)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1>>COC(=O)COc1ccc(-c2ccc3cc(C(=O)OCc4ccccc4)ccc3c2)cc1C12CC3CC(CC(C3)C1)C2,,CN(C)C=O,,Cl,[H-].[Na+],test
US20130096113A1,CS(=O)c1nc2ccc(Cn3cnc4cc(Br)cnc43)cc2o1.N[C@@H]1c2ccccc2C[C@H]1O>>O[C@@H]1Cc2ccccc2[C@H]1Nc1nc2ccc(Cn3cnc4cc(Br)cnc43)cc2o1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,,test
US20130059834A1,CCCC[Sn](Cl)(CCCC)CCCC.Ic1ncn2ccccc12>>CCCC[Sn](CCCC)(CCCC)c1ncn2ccccc12,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20130184253A1,CC(=O)N1CCN[C@H](C)C1.Clc1nc(Cl)c2c(n1)CCN(Cc1ccccc1)C2>>CC(=O)N1CCN(c2nc(Cl)nc3c2CN(Cc2ccccc2)CC3)[C@H](C)C1,,CC(C)O,CCOC(C)=O,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US05026859,COC(=O)c1cc(C=O)cnc1C(=O)OC.OCCCCO>>COC(=O)c1cc(C2OCCCCO2)cnc1C(=O)OC,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20060173184A1,COC(=O)c1ccccc1NC(=O)N1CCN(Cc2cnc3ccccc3c2)CC1>>O=C(O)c1ccccc1NC(=O)N1CCN(Cc2cnc3ccccc3c2)CC1,,C1CCOC1,,,,test
US20070254931A1,COC(=O)CCc1ccc(-c2nc(NC(C)=O)sc2Cc2ccc(S(C)(=O)=O)cc2)cc1>>CC(=O)Nc1nc(-c2ccc(CCC(=O)O)cc2)c(Cc2ccc(S(C)(=O)=O)cc2)s1,,C1COCCO1,,[Na+].[OH-],,test
US20130035318A1,C=C(C)[C@@H]1CC[C@]2(NCC3CCCN(C(=O)OC(C)(C)C)C3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NCC3CCCNC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090036492A1,COCc1cc(C2OCCCO2)c2ccccc2c1>>COCc1cc(C=O)c2ccccc2c1,,CC(=O)O,O,,,test
US20160257670A1,CCOC(=O)C1=NNC2C(=O)N(Cc3ccccc3)C(=O)C12>>CCOC(=O)C1C2C(=O)N(Cc3ccccc3)C(=O)C12,,CCOCC,,,,test
US20110319277A1,CC(=O)Nc1cccc2c1C(=O)N(C1(CCCCNC(=O)OCc3ccccc3)CCC(=O)NC1=O)C2=O.Cl>>CC(=O)Nc1cccc2c1C(=O)N(C1(CCCCN)CCC(=O)NC1=O)C2=O.Cl,[Pd],CCO,,[H][H],,test
US20020156075A1,CN[C@H](CC1CCCCC1)CN1CCC(c2ccccc2OC)CC1.ClCCl.O=C(Cl)C1CCCCC1>>COc1ccccc1C1CCN(C[C@@H](CC2CCCCC2)N(C)C(=O)C2CCCCC2)CC1.Cl,,ClCCl,O,O=C([O-])[O-].[K+].[K+],,test
US20060040961A1,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.CN(C)CC(=O)Cl>>CN(C)CC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20050182045A1,C1CCNCC1.CCc1nc2ccccc2c(=O)n1-c1ccc(OCCCCl)c(Br)c1>>CCc1nc2ccccc2c(=O)n1-c1ccc(OCCCN2CCCCC2)c(Br)c1,,CCOCC,,,,test
US20120088748A1,CI.COCC(=O)NC[C@H]1OCCN(C(=O)OC(C)(C)C)C[C@H]1c1ccc(Cl)c(Cl)c1>>COCC(=O)N(C)C[C@H]1OCCN(C(=O)OC(C)(C)C)C[C@H]1c1ccc(Cl)c(Cl)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20120225888A1,CC(=O)OC(C)(C)C.COC(=O)C(O)c1c(C)nc2cc(-c3cccc(Cl)c3)nn2c1Cl>>COC(=O)C(OC(C)(C)C)c1c(C)nc2cc(-c3cccc(Cl)c3)nn2c1Cl,,ClCCl,,[O-][Cl+3]([O-])([O-])O,,test
US04336401,CC(=O)OC(C)=O.CC1=CCCC(C)(C)C1(O)C#CC(C)O>>CC(=O)OC(C)C#CC1=C(C)C=CCC1(C)C,,COC(C)(C)C,,c1ccncc1,,test
US08030340B2,Br[Mg]c1ccc2c(c1)OCCO2.CON(C)C(=O)[C@H](C)NC(=O)OC(C)(C)C>>C[C@H](NC(=O)OC(C)(C)C)[C@H](O)c1ccc2c(c1)OCCO2,,C1CCOC1,O,CC(C)[Mg]Cl,Cl,test
US20070219210A1,CC(C)(C)NC(=O)c1cc(-c2ccc(C#N)cn2)n(-c2ccccc2)n1>>CC(C)(C)NC(=O)c1cc(-c2ccc(CN)cn2)n(-c2ccccc2)n1,,CCO,,N,,test
US04826836,CC(C)(COc1ccc(Cl)cc1)C1(C)OC(CN2CCCCC2)CS1.O=C1NS(=O)(=O)c2ccccc21>>CC(C)(COc1ccc(Cl)cc1)C1(C)OC(CN2CCCCC2)CS1.O=C1NS(=O)(=O)c2ccccc21,,C1CCOC1,,,,test
US03978071,CC(C(N)=O)c1ccc(C(=O)CCl)cc1.Nc1ccccn1>>CC(C(N)=O)c1ccc(-c2cn3ccccc3n2)cc1,,CCO,,,,test
US20100197960A1,CC(C)OB(OC(C)C)OC(C)C.COc1cc(I)c(I)cc1OC>>COc1cc(I)c(B(O)O)cc1OC,,C1CCOC1,CCOCC,CC(C)[Mg]Cl,[Cl-].[NH4+],test
US20110118470A1,COc1ccc(NC(=O)Nc2ccc(Oc3ccnc4cc([O-])c(C#N)cc34)cc2)cc1.ClCCCN1CCOCC1>>COc1ccc(NC(=O)Nc2ccc(Oc3ccnc4cc(OCCCN5CCOCC5)c(C#N)cc34)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05532258,COCCNC(N)=Nc1nc(-c2cccc(CNC(C)=O)c2)cs1.Cl>>COCCNC(N)=Nc1nc(-c2cccc(CNC(C)=O)c2)cs1.Cl,,CO,,C1COCCO1,,test
US20140045936A1,CN.COC(=O)C1(c2ccccc2)CC1C=O>>CNCC1CC1(C(=O)OC)c1ccccc1,,CO,,[BH4-].[Na+],,test
US20110152257A1,CC(C)(C)C(=O)Nc1ccc(I)cn1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)C(=S)Nc1ccc(I)cn1,,Cc1ccccc1,,,,test
US04886814,COC(=O)COc1ccc(CC(C)NCCO)cc1.Cc1sc(C(F)(F)F)nc1C(=O)CBr>>COC(=O)c1ccc(CC(C)N2CCOC(c3nc(C(F)(F)F)sc3C)C2)cc1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20040116465A1,C1CCNC1.CCOc1ccc(Cc2nc3cc(C(=O)O)ccc3n2CC2CC2)nc1>>CCOc1ccc(Cc2nc3c(C(=O)N4CCCC4)cccc3n2CC2CC2)nc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130172556A1,CCc1cc(C)cc(CC)c1C(=O)C(=O)N(C)N=C(C)CSC>>CCc1cc(C)cc(CC)c1-c1c(SC)c(C)nn(C)c1=O,,C1CCOC1,,O,[H-].[Na+],test
US20160016908A1,CC(=O)N1c2ccc(C(=O)O)cc2[C@H](Nc2cccc(C)n2)[C@@H](C)[C@@H]1C1CC1.CCN>>CCNC(=O)c1ccc2c(c1)[C@H](Nc1cccc(C)n1)[C@@H](C)[C@H](C1CC1)N2C(C)=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050282858A1,O=C(OCc1ccccc1)N1CC(O)C(c2ccccc2)C1>>OC1CNCC1c1ccccc1,[Pd],,,CO,,test
US20110144105A1,CC(C)Oc1cnc2[nH]c(C(=CC3CCCC3)c3ccc(S(C)(=O)=O)cc3)cc2c1>>CC(C)Oc1cnc2[nH]c(C(CC3CCCC3)c3ccc(S(C)(=O)=O)cc3)cc2c1,[Pd],CO,,[H][H],,test
US20110136763A1,CCOC(=O)CC1OB(O)c2cc(OC)cc(COC)c21>>COCc1cc(OC)cc2c1C(CC(=O)O)OB2O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20110136821A1,CC(C)(C)OC(=O)N1CCC2(CC1)CC(N)c1cccc(Br)c12.C[Si](C)(C)CCOC(=O)ON1C(=O)CCC1=O>>CC(C)(C)OC(=O)N1CCC2(CC1)CC(NC(=O)OCC[Si](C)(C)C)c1cccc(Br)c12,,C1CCOC1,CCOCC,O=C([O-])[O-].[K+].[K+],,test
US20070254894A1,CNC.O=[N+]([O-])c1ccccc1F>>CN(C)c1ccccc1[N+](=O)[O-],,C1CCOC1,,,,test
US06143311,C#CCOCOc1ccc(OC)cc1.II>>COc1ccc(OCOCC#CI)cc1,,CO,,[Na+].[OH-],,test
US20050043334A1,CC(=O)OC(C)=O.Cc1ccc(Oc2ccc(Nc3ncnc4ccc(NC5=NC6(CCNCC6)CO5)cc34)cc2C)cn1>>CC(=O)N1CCC2(CC1)COC(Nc1ccc3ncnc(Nc4ccc(Oc5ccc(C)nc5)c(C)c4)c3c1)=N2,,ClCCl,c1ccncc1,,,test
US20110015175A1,C=CCBr.COc1cc(NC(N)=S)c(F)cc1-n1cnc(C)n1>>Br.C=CCSC(=N)Nc1cc(OC)c(-n2cnc(C)n2)cc1F,,CCO,,,,test
US03931200,CNOC.O=C=Nc1ccc(OCc2nc(Cl)ccc2Cl)cc1>>CON(C)C(=O)Nc1ccc(OCc2nc(Cl)ccc2Cl)cc1,,c1ccncc1,,CCN(CC)CC,Cl,test
US20140200227A1,C[C@H]1CN(c2c([N+](=O)[O-])cnc3c2CCC3)C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O.O=C(OO)c1cccc(Cl)c1>>C[C@H]1CN(c2c([N+](=O)[O-])c[n+]([O-])c3c2CCC3)C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O,,ClCCl,,,,test
US20110275611A1,CC[C@@H]1CCCN1c1cc(-c2cc(F)c(C#N)c(F)c2)nc(NC)n1.CS>>CC[C@@H]1CCCN1c1cc(-c2cc(F)c(C#N)c(SC)c2)nc(NC)n1,,CN(C)C=O,,O,[Na],test
US20030060473A1,O=C(NOC1CCCCO1)[C@H]1CNCCN1S(=O)(=O)c1ccc(-c2ccccc2)s1.O=S(=O)(Cl)CCc1ccccn1>>O=C(NOC1CCCCO1)[C@H]1CN(S(=O)(=O)CCc2ccccn2)CCN1S(=O)(=O)c1ccc(-c2ccccc2)s1,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20060148858A1,CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO.COC(=O)C(C)(C)c1cccc(O)c1>>CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCOc1cccc(C(C)(C)C(=O)O)c1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20140045862A1,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)N(C(=O)OC(C)(C)C)c2cscn2)cc1Cl>>Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130331378A1,C[Si](C)(C)Cl.Clc1ccc2cc(N3CCOCC3)nn2c1>>C[Si](C)(C)c1c(Cl)ccc2cc(N3CCOCC3)nn12,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US20020052384A1,C/C=C/C=O.Nc1c[nH]c(=O)[nH]c1=O>>Cc1ccc2[nH]c(=O)[nH]c(=O)c2n1,,Cl,,,,test
US04080330,Clc1ccc(-c2c[nH]c3ccccc23)cc1>>Clc1ccc(C2CNc3ccccc32)cc1,[Zn],CC(=O)O,,CCOCC,FB(F)F,test
US04863942,CCCc1c(OCCCOc2cc(NC(=O)C(=O)OC)c(C)cc2Br)ccc(C(C)=O)c1O>>CCCc1c(OCCCOc2cc(NC(=O)C(=O)O)c(C)cc2Br)ccc(C(C)=O)c1O,,CO,,[Na+].[OH-],,test
US03940259,CCc1cccc(CC)c1N.ClCC1OCCCCO1>>CCc1cccc(CC)c1NCC1OCCCCO1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130035329A1,COc1ccccc1N1CCN(C(=O)OC(C)(C)C)CC1>>COc1ccccc1N1CCNCC1,,CO,Cl,,,test
US20080167289A1,BrCc1ccccc1.CN1C(=O)C(C)(C)CNc2nc(Cl)ncc21>>CN1C(=O)C(C)(C)CN(Cc2ccccc2)c2nc(Cl)ncc21,,CC(=O)N(C)C,,[H-].[Na+],,test
US06245829B1,C=CC(=O)O.CCCCCCCCCCCC1=NCCO1>>C=CC(=O)OCCNC(=O)CCCCCCCCCC,,CCOCC,,,,test
US20150031727A1,CC(C)(C)OC(=O)NCCNC1CC1.COC(=O)c1ccc(CCc2ccc(NC(=O)c3c(NC(=O)c4cccc(CCl)c4)sc4c3CCCC4)cc2)cc1>>COC(=O)c1ccc(CCc2ccc(NC(=O)c3c(NC(=O)c4cccc(CN(CCNC(=O)OC(C)(C)C)C5CC5)c4)sc4c3CCCC4)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050054851A1,CC(=O)Cl.CC(C)(C)Cn1c(Cc2ccc(N)cc2)cc2cnc(C#N)nc21>>CC(=O)Nc1ccc(Cc2cc3cnc(C#N)nc3n2CC(C)(C)C)cc1,,ClCCl,,CCN(CC)CC,,test
US05861421,C#CC1(c2ccc(OC)c(OC3CCCC3)c2)CCC2(CC1)OCCO2.C1CCNCC1.COC(=O)COc1ccc(I)cc1>>COc1ccc(C2(C#Cc3ccc(OCC(=O)N4CCCCC4)cc3)CCC3(CC2)OCCO3)cc1OC1CCCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110251199A1,CNc1ncc2cc(B3OC(C)(C)C(C)(C)O3)ccc2n1.Cc1nc(Nc2cccc(OC(F)(F)F)c2)c2ccc(C)c(I)c2n1>>CNc1ncc2cc(-c3c(C)ccc4c(Nc5cccc(OC(F)(F)F)c5)nc(C)nc34)ccc2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20050261303A1,C1COCCN1.O=[N+]([O-])c1ccc2nc(Cl)cnc2c1>>O=[N+]([O-])c1ccc2nc(N3CCOCC3)cnc2c1,,C1CCOC1,,,,test
US20120230951A1,COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc2cc(B3OC(C)(C)C(C)(C)O3)ccc2[nH]1)C(C)C.COC(=O)N[C@H]1CCc2ccn3c2C1C(=O)C[C@H](c1ncc(-c2ccc(Br)cc2)[nH]1)C3>>COC(=O)N[C@H]1CCc2ccn3c2C1C(=O)C[C@H](c1ncc(-c2ccc(-c4ccc5nc([C@@H]6CCCN6C(=O)[C@@H](NC(=O)OC)C(C)C)[nH]c5c4)cc2)[nH]1)C3,Cl[Pd]Cl,CC(C)(C)O,,O=C([O-])O.[Na+],,test
US20060189627A1,COS(=O)(=O)OC.c1cc(-c2cc[nH]n2)ccn1>>Cn1ccc(-c2ccncc2)n1,,CCCCCC,CCOCC,C1CCOC1,[H-].[Na+],test
US20110306587A1,Cc1ccc2nc(Cl)ccc2c1.OCC1CCN(c2nccnc2C2CNC2)CC1>>Cc1ccc2nc(N3CC(c4nccnc4N4CCC(CO)CC4)C3)ccc2c1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20140243362A1,BrCc1ccncc1.Cc1ccc(N(CC(C)C)S(=O)(=O)c2cccc(CO)c2)c(C)c1>>Cc1ccc(N(CC(C)C)S(=O)(=O)c2cccc(COCc3ccncc3)c2)c(C)c1,,CN(C)C=O,,[H-].[Na+],,test
US03943140,CCOC(=O)/C=C(/C)N.CCOC(=O)CC(=O)C(=O)OCC.[N-]=[N+]=Nc1ccccc1C=O>>CCOC(=O)C1=C(C(=O)OCC)C(c2ccccc2N=[N+]=[N-])C(C(=O)OCC)=C(C)N1,,CCO,,,,test
US20050143381A1,O=c1c(Cl)c(-c2ccc(Cl)cc2)cnn1Cc1ccccc1>>O=c1[nH]ncc(-c2ccc(Cl)cc2)c1Cl,,Cc1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20130116430A1,CCCC(=O)[C@H](C)NC(=O)OC(C)(C)C>>CCCC(O)[C@H](C)NC(=O)OC(C)(C)C,,CC(C)O,CO,[BH4-].[Na+],,test
US04652558,Cl[Sn](c1ccccc1)(c1ccccc1)c1ccccc1.O=c1c2ccc(Cl)cc2nc(S)n1-c1ccccc1>>O=c1c2ccc(Cl)cc2nc(S[Sn](c2ccccc2)(c2ccccc2)c2ccccc2)n1-c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20070027133A1,CCOC(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1OCC=O.NCC(F)(F)F>>CCOC(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1OCCNCC(F)(F)F,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20120010241A1,CC(C)(O)CNc1cc(-n2nc(Br)c3c(-c4cnc5ccccc5c4)cccc32)cnc1C#N.OO>>CC(C)(O)CNc1cc(-n2nc(Br)c3c(-c4cnc5ccccc5c4)cccc32)cnc1C(N)=O,,CCO,CS(C)=O,O,[Na+].[OH-],test
US20090281107A1,CCCI.O=C(O)c1ccc(O)c(F)c1>>CCCOc1ccc(C(=O)O)cc1F,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150018546A1,CCOC(=O)c1cncnc1Cl.O=C(Cc1ccccc1)NOCc1ccccc1>>O=c1c(-c2ccccc2)c(O)c2cncnc2n1OCc1ccccc1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20050101587A9,CCOC(=O)N1CCC(N)CC1.O=[N+]([O-])c1ccc(Cl)cc1F>>CCOC(=O)N1CCC(Nc2cc(Cl)ccc2[N+](=O)[O-])CC1,,CN(C)C=O,ClCCl,,,test
US20110144099A1,CCOCc1nc2c[n+]([O-])c3ccc(OCc4ccccc4)cc3c2n1CC(C)C.O=C=NC(=O)C(Cl)(Cl)Cl>>CCOCc1nc2c(N)nc3ccc(OCc4ccccc4)cc3c2n1CC(C)C,,ClC(Cl)Cl,,C[O-].[Na+],,test
US20130029990A1,COCC(=O)Nc1cc(O)ccn1.O=[N+]([O-])c1ccc(F)c2ncccc12>>COCC(=O)Nc1cc(Oc2ccc([N+](=O)[O-])c3cccnc23)ccn1,,CC#N,,C1CCC2=NCCCN2CC1,O,test
US20090124595A1,Nc1ccc(I)cc1F.O=C(O)c1c(Cl)c(F)c(=O)n2c1CCC2>>O=C(O)c1c(Nc2ccc(I)cc2F)c(F)c(=O)n2c1CCC2,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20040180884A1,O=C(O)c1cccc(F)c1CCc1ccc(Br)cc1>>O=C1c2cc(Br)ccc2CCc2c(F)cccc21,,O,,,,test
US20080064704A1,CC(=O)CC(=O)C1CCCCN1C(=O)OCc1ccccc1.N#Cc1ccc(C=O)cc1.NC(=O)Nc1cccc(C(F)(F)F)c1>>CC1=C(C(=O)C2CCCCN2C(=O)OCc2ccccc2)C(c2ccc(C#N)cc2)NC(=O)N1c1cccc(C(F)(F)F)c1,,COC(C)(C)C,,,,test
US05981533,CN(C)C(OCc1ccccc1)OCc1ccccc1.N#Cc1c(-c2ccc([N+](=O)[O-])cc2)n[nH]c1N>>CN(C)C=Nc1[nH]nc(-c2ccc([N+](=O)[O-])cc2)c1C#N,,Cc1ccccc1,,,,test
US20070244159A1,O=[N+]([O-])c1cccc(F)c1Br>>Nc1cccc(F)c1Br,Cl[Ni]Cl,CO,,O,[BH4-].[Na+],test
US20110294776A1,N#Cc1ccc(Br)cc1F.NNc1ccccc1>>Nc1c2ccc(Br)cc2nn1-c1ccccc1,,CCCCO,,CCN(C(C)C)C(C)C,Cl,test
US20130296377A1,C[Si](C)(C)CCOCCl.Cc1ccc(S(=O)(=O)n2ccc3c(COC4CCCCO4)c(CO)cc(C)c32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(CO)c(COCOCC[Si](C)(C)C)cc(C)c32)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US03961055,CN(C)S(=O)(=O)c1cccc2c1Sc1ccc(O)cc1N2.COS(=O)(=O)OC>>COc1ccc2c(c1)Nc1cccc(S(=O)(=O)N(C)C)c1S2,,CCC(C)=O,,[Na+].[OH-],,test
US04966905,CC1=CC(=O)C(C)(c2ccc(F)cc2)O1.N#Cc1ccc(C=O)cc1>>CC1(c2ccc(F)cc2)OC(C=Cc2ccc(C#N)cc2)=CC1=O,,CCO,,[Na+].[OH-],,test
US20090069305A1,CN1CCNCC1.Cc1ccc(-c2ccnc(Cl)c2)cc1F>>Cc1ccc(-c2ccnc(N3CCN(C)CC3)c2)cc1F,Cl,CC(C)O,,,,test
US20130023566A1,CC(C)(C)[S@](=O)/N=C/c1ccccc1-c1noc2cc(C(N)=O)ccc12.Cc1ccccn1>>CC(C)(C)[S@](=O)N[C@@H](Cc1ccccn1)c1ccccc1-c1noc2cc(C(N)=O)ccc12,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US05374643,Nc1cccc(-c2ncno2)c1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(Nc1cccc(-c2ncno2)c1)Oc1ccc([N+](=O)[O-])cc1,,CC#N,,c1ccncc1,,test
US20160106765A1,COC(=O)[C@@H](N)Cc1ccc(OP(=O)(O)O)c(O)c1>>N[C@@H](Cc1ccc(OP(=O)(O)O)c(O)c1)C(=O)O,,O,,[Na+].[OH-],,test
US20070276000A1,CCS(=O)(=O)Cl.COc1ccc2c(Oc3ccc(N)cc3)c(-c3ccccc3)c(C)cc2c1>>CCS(=O)(=O)Nc1ccc(Oc2c(-c3ccccc3)c(C)cc3cc(OC)ccc23)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20120010190A1,COc1ccc(C(=O)/C=C/c2ccc(Cl)cc2F)cn1>>O=C(/C=C/c1ccc(Cl)cc1F)c1ccc(=O)[nH]c1,,C1COCCO1,,Cl,,test
US20160200710A1,COc1cccnc1CC(=O)Nc1cccc(Br)c1C.O=C(n1ccnc1)n1ccnc1>>COc1cccn2c(=O)n(-c3cccc(Br)c3C)c(=O)cc12,,CCOC(C)=O,Cc1ccccc1,,,test
US20050059723A1,Cc1cc2ccccc2[nH]1.Fc1cc(Br)ccc1OCc1ccccc1>>Cc1cc2ccccc2n1-c1ccc(OCc2ccccc2)c(F)c1,[Cu]Br,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20070129334A1,O=[N+]([O-])c1cc(OC(F)(F)F)ccc1I>>Nc1cc(OC(F)(F)F)ccc1I,,CO,,NN,O,test
US20090005558A1,CC(C)(C)OC(=O)N1CC2CNCC(C1)O2.CN(CC=O)S(=O)(=O)c1ccc(C#N)cc1>>CN(CCN1CC2CN(C(=O)OC(C)(C)C)CC(C1)O2)S(=O)(=O)c1ccc(C#N)cc1,,ClCCl,,CC(=O)O,[BH3-]C#N.[Na+],test
US20100130468A1,CCOC(=O)c1cc(Br)cc2c(C3CCS(=O)(=O)C(C)(C)C3)cn(C(=O)OC(C)(C)C)c12>>CC1(C)CC(c2c[nH]c3c(C(=O)O)cc(Br)cc23)CCS1(=O)=O,,CO,O,Cl,[Na+].[OH-],test
US20090036492A1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.O=Cc1ccccc1>>COc1cc(O)c2c(c1C(=O)NCc1ccccc1)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,Cc1ccccc1,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20110269737A1,COc1c(CO)cc(C(C)(C)C)cc1[N+](=O)[O-].CS(=O)(=O)Cl>>COc1c(COS(C)(=O)=O)cc(C(C)(C)C)cc1[N+](=O)[O-],,ClCCl,,CCN(CC)CC,,test
US06479491B1,COc1ccc(Cl)cc1Br.[O-]B([O-])[O-]>>COc1ccc(Cl)cc1B(O)O,,C1CCOC1,CCOCC,Cl,[Li]CCCC,test
US20060235035A1,COC(=O)c1ccc(N)cc1OC.Nc1ccc(OC(F)(F)F)cc1Br.O=C(Cl)Cl>>COC(=O)c1ccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2Br)cc1OC,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150210722A1,C[Si](C)(C)c1cc(C(=O)O)n(-c2cccc(CP(C)(C)=O)c2)n1.Nc1ccc(Oc2ccnc(Nc3ccccc3)n2)c2ccccc12.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>C[Si](C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccccc4)n3)c3ccccc23)n(-c2cccc(CP(C)(C)=O)c2)n1,,C1COCCO1,,CCN(CC)CC,,test
US20150259457A1,C=CCCCCCCN.CC(O)=S.Cl>>CC(=O)SCCCCCCCCN.Cl,,C1CCOC1,,,,test
US20090298863A1,C=CCn1c(=O)n([C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]2OC(C)=O)c2nc(N)nc(Cl)c21>>C=CCn1c(=O)n([C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H]2OC(C)=O)c2nc(N)ncc21,,CC(=O)O,,,,test
US03998829,C=CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C.[Li]C>>CCCC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C,,CCOCC,,[Cl-].[NH4+],,test
US20110060011A1,Nc1ccc(-c2nc(-c3cccc(Cl)c3)co2)cc1.O=C(Cl)c1ccccc1>>O=C(Nc1ccc(-c2nc(-c3cccc(Cl)c3)co2)cc1)c1ccccc1,,CCOC(C)=O,,ClCCl,c1ccncc1,test
US20060111413A1,O=C(N[C@@H]1Cc2ccccc2C[C@H]1O)OCc1ccccc1>>O=C(NC1Cc2ccccc2CC1=O)OCc1ccccc1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20090181928A1,CI.C[Si](C)(C)CCN1C(=O)CN(c2ccc(C=Cc3cn[nH]c3)cc2OCc2ccccc2)S1(=O)=O>>Cn1cc(C=Cc2ccc(N3CC(=O)N(CC[Si](C)(C)C)S3(=O)=O)c(OCc3ccccc3)c2)cn1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100311748A1,COc1ccc(CO)nc1.Cc1ccc(-c2ncc[nH]2)cc1NC(=O)c1ccc(O)cc1>>COc1ccc(COc2ccc(C(=O)Nc3cc(-c4ncc[nH]4)ccc3C)cc2)nc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030186992A1,COc1ccc2ccccc2c1CCCCN1CCNCC1.Fc1ccc(C2CO2)cc1>>COc1ccc2ccccc2c1CCCCN1CCN(CC(O)c2ccc(F)cc2)CC1,,CCO,,,,test
US20090285881A1,CCCCC/C=C\C/C=C\CCCCCCCCOCC(CO)COCCCCCCCC/C=C\C/C=C\CCCCC.O=C([O-])Oc1ccc([N+](=O)[O-])cc1>>CCCCC/C=C\C/C=C\CCCCCCCCOCC(COCCCCCCCC/C=C\C/C=C\CCCCC)COC(=O)Oc1ccc([N+](=O)[O-])cc1,,ClCCl,,CCN(CC)CC,,test
US20100158996A1,COC(=O)C(C(=O)OC(C)(C)C)c1ccc([N+](=O)[O-])c(Br)c1>>COC(=O)Cc1ccc([N+](=O)[O-])c(Br)c1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20150099777A1,CC(C)(C)OC(=O)N1CCC(N)CC1.O=CCc1ccc(Cl)nc1Cl>>CC(C)(C)OC(=O)N1CCC(NCCc2ccc(Cl)nc2Cl)CC1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US05268378,COC(=O)c1ccc(Cl)cc1N.O=C(O)Cc1ccsc1>>COC(=O)c1ccc(Cl)cc1NC(=O)Cc1ccsc1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20070249670A1,COC(=O)C(NC(=O)OCc1ccccc1)P(=O)(OC)OC.O=CCCC(F)(F)F>>COC(=O)/C(=C\CCC(F)(F)F)NC(=O)OCc1ccccc1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US04267193,Cc1cccc(C)c1N.NC(=O)CCl>>Cc1cccc(C)c1NCC(N)=O,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100021423A1,COc1c(C(=O)c2cccc(C#N)c2)cc(-c2ccc[nH]c2=O)cc1C(C)(C)C>>COc1c(C(=O)c2cccc(CN)c2)cc(-c2ccc[nH]c2=O)cc1C(C)(C)C,[Ni],,,,,test
US20060106048A1,CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C(N)=O)c(NCc3ccccc3)c1)=NC(C)(C)C2>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(C#N)c(NCc3ccccc3)c1)=NC(C)(C)C2,,ClC(Cl)Cl,,O=P(Cl)(Cl)Cl,O=C([O-])O.[Na+],test
US20040077646A1,CCOC(=O)c1cc2ccccc2n1CCOCCO.CI>>CCOC(=O)c1cc2ccccc2n1CCOCCOC,,CN(C)C=O,,O,[H-].[Na+],test
US20050049203A1,COc1ccc(C(O)c2c(C)cc(OC)nc2OC)cc1>>COc1cc(C)c(C(=O)c2ccccc2OC)c(OC)n1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20050043537A1,CCOc1ccc([N+](=O)[O-])cc1I>>CCOc1ccc(N)cc1I,[Fe],CCO,O,[Cl-].[NH4+],,test
US20050107409A1,CC(C)(C)OC(=O)NC(Cc1ccccc1)c1cc(C#N)ccc1OCc1ccccc1>>N#Cc1ccc(OCc2ccccc2)c(C(N)Cc2ccccc2)c1,,C1COCCO1,,Cl,,test
US06090813,Brc1ccc(OC2CCNCC2)cc1.O=C(Cl)C1CCN(c2ccncc2)CC1>>O=C(C1CCN(c2ccncc2)CC1)N1CCC(Oc2ccc(Br)cc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20160264518A1,COC(=O)CCc1ccc2nc(CNc3ccccc3Br)[nH]c2c1>>OCCCc1ccc2nc(CNc3ccccc3Br)[nH]c2c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US09409922B2,COC(CBr)(OC)c1cccc(Br)c1.Cc1cc(N)nc(Cl)c1C(=O)OC(C)(C)C>>Cc1cc2nc(-c3cccc(Br)c3)cn2c(Cl)c1C(=O)OC(C)(C)C,,Clc1ccccc1,,,,test
US20150065464A1,O=C(NC1CCC(=Cc2cccc(Oc3ccc(C(F)(F)F)cn3)c2)CC1)c1ccc(Cl)nc1.O=C1CCCN1>>O=C(NC1CCC(=Cc2cccc(Oc3ccc(C(F)(F)F)cn3)c2)CC1)c1ccc(N2CCCC2=O)nc1,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=C([O-])[O-].[K+].[K+],test
US20140086834A1,COc1ccc(-c2ccccc2N2CCNCC2)cc1.O=C(CCCCCBr)NCc1ccccn1>>COc1ccc(-c2ccccc2N2CCN(CCCCCC(=O)NCc3ccccn3)CC2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04657898,CC(=O)N1CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C2C1=C(Cl)N(C(C)=O)C(Cl)N2C(C)=O.NCC(c1ccccc1)c1ccccc1>>OC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O,,COCCOC,,CCN(CC)CC,,test
US20080207902A1,CCC(=O)c1ccc(OC)n2nc(C(F)(F)F)cc12.OCc1ccccc1>>COc1ccc(C(=O)CCOCc2ccccc2)c2cc(C(F)(F)F)nn12,,ClCCl,,,,test
US20110212937A1,CCNC.Clc1nc(Cl)c2c(n1)C(c1ccccc1)COC2>>CCN(C)c1nc(Cl)nc2c1COCC2c1ccccc1,,CO,,,,test
US20110034526A1,CS(=O)(=O)c1cccc(Oc2cccc(I)c2)c1.Cc1nc2cccc(C(F)(F)F)c2[nH]1>>Cc1nc2c(C(F)(F)F)cccc2n1-c1cccc(Oc2cccc(S(C)(=O)=O)c2)c1,[Cu]I,CN(C)C=O,,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US20160052884A1,CC(C(=O)OC(C)(C)C)n1ccc(Br)cc1=O.OB(O)c1cc(Cl)ccc1Cl>>CC(C(=O)OC(C)(C)C)n1ccc(-c2cc(Cl)ccc2Cl)cc1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US05861414,BrCc1ccccc1.CC(C)(C)OC(=O)CN1CCC(c2n[nH]c3cc(/C=C/C4CCN(C(=O)OC(C)(C)C)CC4)ccc23)CC1>>CC(C)(C)OC(=O)CN1CCC(c2nn(Cc3ccccc3)c3cc(/C=C/C4CCN(C(=O)OC(C)(C)C)CC4)ccc23)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20070043083A1,CC(C)(C)OC(=O)N1CCC(C(N)=S)CC1.O=C(CBr)c1ccccc1>>Br.c1ccc(-c2csc(C3CCNCC3)n2)cc1,,CO,,,,test
US20160251340A1,CC(C)(C)OC(=O)NC(C)(C)C(=O)Nc1ccc(Oc2cccc3c2C2CC2(C)CO3)nc1>>CC(C)(N)C(=O)Nc1ccc(Oc2cccc3c2C2CC2(C)CO3)nc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04829071,CNC1Cc2ccc([N+](=O)[O-])cc2C1.O=[N+]([O-])c1ccc2oc(CBr)cc2c1>>CN(Cc1cc2cc([N+](=O)[O-])ccc2o1)C1Cc2ccc([N+](=O)[O-])cc2C1,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20090298878A1,CC(=O)Cl.O=S(=O)(c1ccc(OC(F)(F)F)cc1)N1CCC(=NOCC2CCCNC2)CC1>>CC(=O)N1CCCC(CON=C2CCN(S(=O)(=O)c3ccc(OC(F)(F)F)cc3)CC2)C1,,CC(Cl)Cl,,CCN(CC)CC,,test
US04277394,C[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)OC(C)(C)C>>C[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NN,,O=C(O)C(F)(F)F,,,,test
US20150038488A1,Brc1ccncn1.C[C@@H](Oc1cc(B2OC(C)(C)C(C)(C)O2)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1>>C[C@@H](Oc1cc(-c2ccncn2)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20130096118A1,COC(=O)c1cc(C)ccc1C.O=C1CCC(=O)N1Br>>COC(=O)c1cc(C)ccc1CBr,,c1ccccc1,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US07230023B2,C=CCOP(=O)(OCC=C)OCc1ccc(COC(C)=O)c(C(=O)O)c1.O=C(Cl)C(=O)Cl>>C=CCOP(=O)(OCC=C)OCc1ccc(COC(C)=O)c(C(=O)Cl)c1,,C1CCOC1,,CN(C)C=O,,test
US20020019436A1,C1CCNCC1.C=O.CC(=O)c1cc(C(=O)c2cccc3ccccc23)n(C)c1>>Cn1cc(C(=O)CCN2CCCCC2)cc1C(=O)c1cccc2ccccc12,,CO,,Cl,[Na+].[OH-],test
US20100099684A1,CCOC(=O)N=C=S.Cc1cnc(N)c(Br)n1>>CCOC(=O)Nc1nc2ncc(C)nc2s1,,CO,,Cc1ccccc1,,test
US05330986,FC(F)(F)c1cccc(N2CCNCC2)c1.O=C(O)c1cccc2cc[nH]c12>>O=C(c1cccc2cc[nH]c12)N1CCN(c2cccc(C(F)(F)F)c2)CC1,,CN(C)C=O,,,,test
US20060009471A1,CI.COC(=O)Cc1ccc(Cl)cc1>>COC(=O)C(C)c1ccc(Cl)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20090042872A1,O=Cc1cc(Br)ccc1OCCBr.Oc1cccc(Br)c1>>O=Cc1cc(Br)ccc1OCCOc1cccc(Br)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080227791A1,C1CC2(CCN1)OCCO2.O=Cc1ccc(F)c(F)c1>>Fc1ccc(CN2CCC3(CC2)OCCO3)cc1F,,CC(Cl)Cl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20080207654A1,CCCc1nc(C)c(Cc2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCc1nc(C)c(Cc2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US20050197350A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](CN)CC1.O=C(Cl)c1cccc([N+](=O)[O-])c1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@H](CNC(=O)c2cccc([N+](=O)[O-])c2)CC1,,ClCCl,,,,test
US20090029975A1,CC(C)(C)OC(=O)CCc1cc(S(C)(=O)=O)cc(C#N)n1.COC(=O)c1ccc(Cl)cc1S>>CC(C)(C)OC(=O)CCc1cc(S(C)(=O)=O)cc(-c2nc(=O)c3ccc(Cl)cc3s2)n1,,Cc1ccccc1,,CCN(CC)CC,,test
US05728686,CCI.CCOCn1cnc2c1c(=O)[nH]c(=O)n2C>>CCOCn1cnc2c1c(=O)n(CC)c(=O)n2C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120322837A1,CC(C)(C)OC(=O)CC(CCO)C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1.CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)CC(CCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1,,O,,CN(C)C=O,c1c[nH]cn1,test
US20150175540A1,C1COCCN1.CC(=O)[C@@H]1CC[C@@H](CN2Cc3ccc(O)c(F)c3C2=O)CC1>>CC([C@@H]1CC[C@@H](CN2Cc3ccc(O)c(F)c3C2=O)CC1)N1CCOCC1,,C1CCOC1,ClCCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04036843,CC(C)(N)CO.ClCCl.O=C(Cl)OCc1ccccc1>>CC(=O)OCC(C)(C)N.Cl,,ClCCl,,,,test
US20090311217A1,CN(CCN)C(=O)OC(C)(C)C.Nc1ccc2c(c1)C(=O)CO2.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CN(CCNC(=O)Nc1ccc2c(c1)C(=O)CO2)C(=O)OC(C)(C)C,,C1CCOC1,,CCN(CC)CC,,test
US04140715,C=CC(=O)NC(C)(C)CC(C)=O.O>>C=CC(N)=O.CC(C)=O.CC(C)=O,,O,,N,,test
US20090181963A1,CCn1nnc2c(N3CCOCC3)nc(-c3ccc(N)cc3)nc21.Nc1ccc(C(=O)Nc2cccnc2)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCn1nnc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(C(=O)Nc5cccnc5)cc4)cc3)nc21,,ClCCl,,CCN(CC)CC,,test
US20040102360A1,NC(=O)c1[nH]c2c(N)cccc2c1S(=O)(=O)N1CCOCC1.O=Cc1ccncc1>>NC(=O)c1[nH]c2c(NCc3ccncc3)cccc2c1S(=O)(=O)N1CCOCC1,,CO,,[BH4-].[Na+],,test
US04631282,CC1(C)Oc2ccc(C#N)cc2C2OC21.CCOC(=O)CN>>CCOC(=O)C=N[C@@H]1c2cc(C#N)ccc2OC(C)(C)[C@H]1O,,CCO,,Cl,[Na+].[OH-],test
US20060205787A1,CC1(N2C(=O)c3cccc(N)c3C2=O)CCC(=O)NC1=O.O=C(Cl)CCl>>CC1(N2C(=O)c3cccc(NC(=O)CCl)c3C2=O)CCC(=O)NC1=O,,C1CCOC1,,,,test
US20100137299A1,O=C1N(C[C@@H]2CCCO2)c2ccccc2C12COc1cc3c(cc12)CCO3>>O=C1N(C[C@@H]2CCCO2)c2ccccc2[C@]12COc1cc3c(cc12)CCO3,,COC(C)(C)C,,,,test
US20120252805A1,COc1cccc(-c2c(C#CCO)sc3nc(C)cc(NS(=O)(=O)c4cccc(Cl)c4)c23)c1.CS(=O)(=O)Cl>>COc1cccc(-c2c(C#CCOS(C)(=O)=O)sc3nc(C)cc(NS(=O)(=O)c4cccc(Cl)c4)c23)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090156571A1,CC(C)(C)OC(=O)N1CC(N)C1.O=C(O)c1ccc(-c2cc(Cl)c(CC3CCN(C4CCCCC4)C3=O)c(Cl)c2)cc1>>O=C(NC1CNC1)c1ccc(-c2cc(Cl)c(CC3CCN(C4CCCCC4)C3=O)c(Cl)c2)cc1,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20080275054A1,CN1CCC(c2nc(Cl)c3cnn(C)c3n2)CC1.COc1ccc(C(=O)Nc2ccc(C)c(N)c2)cc1C(F)(F)F>>COc1ccc(C(=O)Nc2ccc(C)c(Nc3nc(C4CCN(C)CC4)nc4c3cnn4C)c2)cc1C(F)(F)F,,CC(C)(C)O,,,,test
US05663440,O=[N+]([O-])c1ccc(Cc2ccc(CCCCCCc3ccc(Cc4ccc([N+](=O)[O-])cc4)cc3)cc2)cc1>>Nc1ccc(Cc2ccc(CCCCCCc3ccc(Cc4ccc(N)cc4)cc3)cc2)cc1,[Pd],C1CCOC1,,O,[H][H],test
US20110053906A1,COC(=O)c1ccc2c(c1)c(=O)[nH]c1nccc(Nc3ccc(NC(=O)c4ccccc4)cc3)c12>>O=C(O)c1ccc2c(c1)c(=O)[nH]c1nccc(Nc3ccc(NC(=O)c4ccccc4)cc3)c12,,C1CCOC1,,O,[Li+].[OH-],test
US20140023642A1,COC(=O)c1cccc(N)c1.NC(=O)c1ccccc1Br.O=C(Cl)C(=O)Cl>>COC(=O)c1cccc(NC(=O)NC(=O)c2ccccc2Br)c1,,ClCCl,,,,test
US20070213331A1,CC(C)(C)OC(=O)N1C[C@H](OCc2ccccc2)C[C@@H]1[C@@H](O)[C@H](Cc1cc(F)cc(F)c1)[N+](=O)[O-]>>CC(C)(C)OC(=O)N1C[C@H](OCc2ccccc2)C[C@@H]1[C@@H](O)[C@@H](N)Cc1cc(F)cc(F)c1,Cl[Ni]Cl,CO,,O,[BH4-].[Na+],test
US20130090309A1,CO.O=C(O)c1ccc2c(c1)C(=O)CC2>>COC(=O)c1ccc2c(c1)C(=O)CC2,,CO,ClCCl,C[Si](C)(C)C=[N+]=[N-],,test
US20080027041A1,COc1ccc(C2=NNC(=O)C(C)C2)cc1>>COc1ccc(-c2cc(C)c(=O)[nH]n2)cc1,,CC#N,,,,test
US05378728,CC(C)(C)C(=O)c1ccc(C(=O)O)cc1.OCCO>>CC(C)(C)C1(c2ccc(C(=O)O)cc2)OCCO1,,Cc1ccccc1,,Cc1ccccc1S(=O)(=O)O,,test
US20160090381A1,COc1cc(C#N)cc(C(=O)Nc2cnc3c(c([C@@H]4CCN(C(=O)C5CCCC5)C(C)(C)C4)cn3C)c2C)c1>>Cc1c(NC(=O)c2cc(O)cc(C#N)c2)cnc2c1c([C@@H]1CCN(C(=O)C3CCCC3)C(C)(C)C1)cn2C,,ClCCl,,BrB(Br)Br,O,test
US20150307477A1,CN.Clc1nc(-c2cccnc2)nc2cc(Br)ccc12>>CNc1nc(-c2cccnc2)nc2cc(Br)ccc12,,C1CCOC1,,,,test
US06414031B1,CC1CCC(C=O)CC1.CC[Mg]Cl>>CCC(O)C1CCC(C)CC1,,C1CCOC1,,Cl,[Cl-].[NH4+],test
US06013649,COC(=O)C(CS(=O)(=O)c1ccc(OC)cc1)NC(C)=O.Cl>>COc1ccc(S(=O)(=O)CC(N)C(=O)O)cc1.Cl,,CC(=O)O,Cc1ccccc1,,,test
US05569780,C=CC1CC1(C(=O)OC)C(=O)OC.Cl>>C=CC(Cl)CC(C(=O)OC)C(=O)OC,,COCCOC,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20130172302A1,O=C(O)C(c1ccccc1)N1CCCC1=O.O[C@H]1CN2CCC1CC2>>O=C(O[C@H]1CN2CCC1CC2)C(c1ccccc1)N1CCCC1=O,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20130210796A1,CC(=O)Cl.N#Cc1ccc(-n2nnnc2CN2CCNCC2)cc1C(F)(F)F>>CC(=O)N1CCN(Cc2nnnn2-c2ccc(C#N)c(C(F)(F)F)c2)CC1,,ClCCl,,CCN(CC)CC,O,test
US20100305145A1,COC(=O)/C=C/c1ccc2nc(C)sc2c1>>COC(=O)CCc1ccc2nc(C)sc2c1,[Pd],CCOC(C)=O,,,,test
US20110230458A1,CC(C)(C)OC(=O)N1CC[C@@H](C(F)F)[C@H](O)C1.CCCCc1nnc(Cl)cc1-c1ccc(OC2CCCCC2)cc1>>CCCCc1nnc(O[C@@H]2CN(C(=O)OC(C)(C)C)CC[C@H]2C(F)F)cc1-c1ccc(OC2CCCCC2)cc1,,C1CCOC1,,[H-].[Na+],,test
US04692456,O=C1c2ccccc2C(=O)N1CCCBr.c1ccc(Nc2ccccn2)cc1>>O=C1c2ccccc2C(=O)N1CCCN(c1ccccc1)c1ccccn1,,CS(C)=O,O,[H][H],[H-].[Na+],test
US20070043035A1,CC(=CCO)c1ccc(-c2ccccc2)cc1.CC(C)OC(=O)/N=N/C(=O)OC(C)C.CCOC(C)=O.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CCOC(=O)C(C)(C)Oc1ccc(OCC=C(C)c2ccc(-c3ccccc3)cc2)cc1,,C1CCOC1,,,,test
US20060148858A1,CCCC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1C=O.CCOC(=O)CP(=O)(OCC)OCC>>CCCC(C)c1nn(-c2ccc(C(F)(F)F)cn2)cc1/C=C/C(=O)OCC,,O,,CN(C)C=O,[H-].[Na+],test
US20160244438A1,C1COCCN1.CC(C)OC(=O)[C@@H](C)OC(=O)C1=C(CBr)NC(c2nccs2)=N[C@@H]1c1ccc(F)cc1Cl>>CC(C)OC(=O)[C@@H](C)OC(=O)C1=C(CN2CCOCC2)NC(c2nccs2)=N[C@@H]1c1ccc(F)cc1Cl,,CC(C)O,,,,test
US20130079544A1,CCCCCCCC(=O)c1ccc(OC(=O)OCC)c(C(=O)O)c1.O=S(Cl)Cl>>CCCCCCCC(=O)c1ccc(OC(=O)OCC)c(C(=O)Cl)c1,c1ccncc1,Cc1ccccc1,,,,test
US20120258953A1,FC(F)(F)c1ccccn1>>FC(F)(F)C1CCCCN1,O=[Pt],CC(=O)O,Cl,,,test
US20060160794A1,CC(=O)Cl.O=C(c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1N1CCNCC1)N1CCC[C@@H]1c1ccccc1Cl>>CC(=O)N1CCN(c2c(C(=O)N3CCC[C@@H]3c3ccccc3Cl)nnn2Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1,,ClCCl,O,CCN(CC)CC,,test
US20110201603A1,Cc1cc(C(O)(C(F)(F)F)C(F)(F)F)cc(C)c1N.O=C(Cl)c1cccc([N+](=O)[O-])c1>>Cc1cc(C(O)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1cccc([N+](=O)[O-])c1,,C1CCOC1,COC(C)(C)C,O,c1ccncc1,test
US20120172599A1,CC1=C(C#N)C(=C(C#N)C#N)OC1(C)C.CCCCN(CCCC)c1ccc(C=Cc2ccc(C=O)cc2)c(OC)c1>>CCCCN(CCCC)c1ccc(C=Cc2ccc(C=CC3=C(C#N)C(=C(C#N)C#N)OC3(C)C)cc2)c(OC)c1,,C1CCOC1,CCO,C,O=C[O-].[NH4+],test
US04925944,CCOC(=O)c1cc(CC)cnc1C>>CCc1cnc(C)c(C(=O)O)c1,,CO,O,Cl,[Na+].[OH-],test
US20090069586A1,CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COC(=O)CCCCCCC/C=C\CCCCCCCC)OC(=O)CCCCCCC/C=C\CCCCCCCC.CO>>CCCCCCCC/C=C\CCCCCCCC(=O)OC,,OCC(O)CO,,,,test
US05202356,CC(C)C(C)NC(=O)/C=C/C=C/[C@@H]1C[C@H]1c1ccc(C=C(Br)Br)cc1.O>>C#Cc1ccc([C@@H]2C[C@H]2CO)cc1,,C1CCOC1,,[Li]CCCC,,test
US20060142265A1,CN.O=Cc1sc2ccccc2c1Cl>>CNCc1sc2ccccc2c1Cl,,CO,,[BH4-].[Na+],,test
US04973721,CC(=O)O[C@H]1C[C@H](OC(C)=O)CC2=CC[C@H]3[C@@H]4CC[C@H]([C@H](C)[C@H](O)C#CC(C)(C)OC5CCCCO5)[C@@]4(C)CC[C@@H]3[C@]21C.CI>>CO[C@H](C#CC(C)(C)OC1CCCCO1)[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(C)=O)C[C@H](OC(C)=O)[C@]4(C)[C@H]3CC[C@]12C,,CCOC(C)=O,CS(C)=O,[K],,test
US05856274,CC(=O)O.CC(=O)OC(C)=O.CSc1c(Cl)ccc(C(=O)CC(=O)C2CC2)c1SC>>CCOC=C(C(=O)c1ccc(Cl)c(SC)c1SC)C(=O)C1CC1,,CC(=O)O,,,,test
US20140005167A1,CC(C)C(O)c1ccccc1Cl>>CC(C)C(=O)c1ccccc1Cl,,CCOCC,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20060166983A1,CCOC(=O)CBr.COc1ccc2[nH]c(C)cc2c1>>CCOC(=O)Cn1c(C)cc2cc(OC)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20140023611A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=C(OCc1ccccc1)c1cccc(C#CCOCCOCCOCCOCCO)c1>>Cc1ccc(S(=O)(=O)OCCOCCOCCOCCOCC#Cc2cccc(C(=O)OCc3ccccc3)c2)cc1,,ClCCl,,CCN(CC)CC,,test
US20070049593A1,CCOC(=O)c1ccc(N)cc1.O=C1CCCCC1>>CCOC(=O)c1ccc(NC2CCCCC2)cc1,,C1CCOC1,CC(=O)O,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160184318A1,Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)N2CCC(O)CC2)n1.Oc1ccc(C(F)(F)F)cn1>>Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)N2CCC(Oc3ccc(C(F)(F)F)cn3)CC2)n1,,ClCCl,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080269193A1,CC1(C)CC(=O)CC(=O)C1.CCC(=O)C=NO>>CCc1c[nH]c2c1C(=O)CC(C)(C)C2,[Zn],CC(=O)O,O,,,test
US20150336967A1,CCn1c(Br)nc2c([N+](=O)[O-])c(Br)c(Br)cc21.O=C1CNCCN1>>CCn1c(N2CCNCC2=O)nc2c([N+](=O)[O-])c(Br)c(Br)cc21,,CCO,,,,test
US20110003787A1,COC[C@H](C)Oc1cc(Oc2cnc(S(C)(=O)=O)cn2)cc(-c2ccc(C3=NC[C@H](CO[Si](C(C)C)(C(C)C)C(C)C)O3)[nH]2)c1>>COC[C@H](C)Oc1cc(Oc2cnc(S(C)(=O)=O)cn2)cc(-c2ccc(C3=NC[C@H](CO)O3)[nH]2)c1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20090318415A1,Nc1ccccc1Sc1ccc(F)cc1C(=O)O>>O=C1Nc2ccccc2Sc2ccc(F)cc21,,Cc1ccccc1C,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US03954438,CCn1c(C)nc2cc(C(F)(F)F)c(Cl)cc21.O=[N+]([O-])O>>CCn1c(C)nc2cc(C(F)(F)F)c(Cl)c([N+](=O)[O-])c21,,ClC(Cl)Cl,,O=S(=O)(O)O,,test
US20040116694A1,COc1ccc(F)cc1C(C)(C)CC(O)(CNc1cccc2nc(COC(C)=O)ccc12)C(F)(F)F>>COc1ccc(F)cc1C(C)(C)CC(O)(CNc1cccc2nc(CO)ccc12)C(F)(F)F,,C1CCOC1,CO,[BH4-].[Na+],,test
US20060287300A1,CC(=O)NC1(CCC(C)(C)C)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21>>CC(C)(C)CCC1(N)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21,,C1COCCO1,,Cl,,test
US20050222139A1,CNCc1cccc(C(=O)N2CC(=O)Nc3ccccc32)c1.O=S(=O)(Cl)c1ccc(Br)cc1>>CN(Cc1cccc(C(=O)N2CC(=O)Nc3ccccc32)c1)S(=O)(=O)c1ccc(Br)cc1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20030040437A1,C=C(C)C(C)=O.COC(=O)C(OC)C(=O)OC>>COC(=O)C1(OC)CC(C)C(=O)C=C1O,,CS(C)=O,,Cl,C[O-].[Na+],test
US20070244110A1,Nc1ccccc1N.O=C(O)C(F)F>>FC(F)c1nc2ccccc2[nH]1,,Cl,,O=C([O-])[O-].[Na+].[Na+],,test
US20100093730A1,Fc1ccc2c(c1)CNC2.O=C(O)CN1CCC(c2ccc(F)cc2)C1=O>>O=C(CN1CCC(c2ccc(F)cc2)C1=O)N1Cc2ccc(F)cc2C1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20120065191A1,CN(C(=O)n1cnc(-c2cccc([N+](=O)[O-])c2)c1)C1CCCCC1>>CN(C(=O)n1cnc(-c2cccc(N)c2)c1)C1CCCCC1,[Pd],CCOC(C)=O,CO,,,test
US20020045747A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)NC1N=C(c2ccccn2)c2ccccc2N(C)C1=O>>C[C@H](N)C(=O)NC1N=C(c2ccccn2)c2ccccc2N(C)C1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US04032323,CCCC(=N)CC(=O)OCC.O=C(N=C=S)Oc1ccccc1>>CCCC(=N)C(C(=O)OCC)C(=S)NC(=O)Oc1ccccc1,,Cc1ccccc1,,,,test
US20040152693A1,CC(=O)CCl.CC1Cc2cc3c(cc2C(c2ccc([N+](=O)[O-])cc2)=NN1C(N)=S)OCO3>>Cc1csc(N2N=C(c3ccc([N+](=O)[O-])cc3)c3cc4c(cc3CC2C)OCO4)n1,,O,,CN(C)C=O,,test
US20160102083A1,COC(=O)c1csc(C(=O)CCCCl)c1C.NC1CCOCC1>>COC(=O)c1csc(C2CCCN2C2CCOCC2)c1C,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20090029905A1,Cc1ccc(S(=O)(=O)O[C@@H]2CCOC2)cc1.Cn1ccc(NC(=O)c2cc(O)cc(OCc3ccccc3)c2)n1>>Cn1ccc(NC(=O)c2cc(OCc3ccccc3)cc(O[C@H]3CCOC3)c2)n1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060228331A1,CC(C)(C)OC(=O)NOCCCCN1C(=O)c2ccccc2C1=O>>CC(C)(C)OC(=O)NOCCCCN,,CCO,,NN,O,test
US20100152175A1,CN(C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnc(N2C[C@H]3COCCN3C[C@H]2CO[Si](C)(C)C(C)(C)C)cc1-c1ccccc1CO>>CN(C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnc(N2C[C@H]3COCCN3C[C@H]2CO)cc1-c1ccccc1CO,Cl,CO,,,,test
US20040092533A1,Brc1cccc(Br)n1.CCCC[Sn](CCCC)(CCCC)c1cnc2nc(C(F)(F)F)ccn12>>FC(F)(F)c1ccn2c(-c3cccc(Br)n3)cnc2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20040138269A1,CCOC(=O)c1[nH]c(C)c(-c2cccc(C(=O)O)c2)c1C.Nc1ccc(Br)cc1F>>CCOC(=O)c1[nH]c(C)c(-c2cccc(C(=O)Nc3ccc(Br)cc3F)c2)c1C,,CCOC(C)=O,ClCCl,O=C(Cl)C(=O)Cl,O=C([O-])O.[Na+],test
US06025387,COc1ccc(-c2cc(=O)c3c(OC)cc(O)cc3o2)cc1OC.OCCBr>>COc1ccc(-c2cc(=O)c3c(OC)cc(OCCO)cc3o2)cc1OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110257151A1,CCOC(=O)c1ccc(N)cc1.O=Cc1cc(Br)ccc1F>>CCOC(=O)c1ccc(N=Cc2cc(Br)ccc2F)cc1,,CCO,,,,test
US04602012,O=C(Cc1cccs1)N[C@@H]1C(=O)N2C(C(=O)O)=C(CO)CS[C@H]12.O=C=NC(=O)C(Cl)(Cl)Cl>>O=C(Cc1cccs1)N[C@@H]1C(=O)N2C(C(=O)O)=C(COC(=O)NC(=O)C(Cl)(Cl)Cl)CS[C@H]12,,CCOC(C)=O,,,,test
US20140194469A1,COC(=O)c1ccnc(-n2nccc2OCc2ccc(C#N)cc2)c1>>N#Cc1ccc(COc2ccnn2-c2cc(C(=O)O)ccn2)cc1,,CC#N,O,,,test
US20020115674A1,C1CCNC1.O=c1c2cc(F)c(F)cc2n(CCF)c(=O)n1OCc1ccccc1>>O=c1c2cc(F)c(N3CCCC3)cc2n(CCF)c(=O)n1OCc1ccccc1,,CC#N,,CCN(CC)CC,,test
US04336261,CC(C)(N)CCc1ccccc1.OCC1CO1>>CC(C)(CCc1ccccc1)NCC(O)CO,,CC(C)O,,,,test
US20090029965A1,Cc1cc(C(=O)O)ccc1CC(=O)N1CCN(CC2CCC2)CC1.Cn1ncc2c1Nc1ccccc1NC2>>Cc1cc(C(=O)N2Cc3cnn(C)c3Nc3ccccc32)ccc1CC(=O)N1CCN(CC2CCC2)CC1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160244451A1,O=[N+]([O-])c1ccnc(C2CCOCC2)c1>>Nc1ccnc(C2CCOCC2)c1,[Pd],CO,,[H][H],,test
US06399621B1,CC(=O)N(C)c1cccc(C(=O)C=CN(C)C)c1.Nc1n[nH]cc1C(=O)c1cccs1>>C=C(C(=O)c1cccs1)N(C)C,,CC(=O)O,,,,test
US20090149458A1,C1CCNC1.C=O.Cn1ccc2nc(-c3cccc(CO)c3)nc(N3CCOCC3)c21>>Cn1cc(CN2CCCC2)c2nc(-c3cccc(CO)c3)nc(N3CCOCC3)c21,,CC(=O)O,,,,test
US20140080800A1,CC(C)(C)OC(=O)N1CCC(CN)CC1.Nc1cc(-c2cccs2)ccc1[N+](=O)[O-].O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)(C)OC(=O)N1CCC(CNC(=O)Nc2cc(-c3cccs3)ccc2[N+](=O)[O-])CC1,,ClCCl,,,,test
US20070066677A1,CC(C)(C)OC(=O)N[C@H](C(=O)N1C[C@@H](F)C[C@H]1C#N)C(c1ccc(F)cc1)c1ccc(F)cc1.Cc1ccc(S(=O)(=O)O)cc1>>Cc1ccc(S(=O)(=O)O)cc1.N#C[C@@H]1C[C@H](F)CN1C(=O)[C@@H](N)C(c1ccc(F)cc1)c1ccc(F)cc1,,CCO,,,,test
US20150225394A1,CC(C)(C)OC(=O)N1CC(CC#N)(N2CCC(N(C(=O)C(F)(F)F)[C@@H]3C[C@H]3c3ccccc3)CC2)C1>>N#CCC1(N2CCC(N(C(=O)C(F)(F)F)[C@@H]3C[C@H]3c3ccccc3)CC2)CNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110312905A1,O=S(=O)(Cl)c1ccccc1.O=c1cccccc1O>>O=c1cccccc1OS(=O)(=O)c1ccccc1,,c1ccncc1,,,,test
US20030144299A1,CCN(CC)C(=O)c1cccc([C@H](c2cccc(OC)c2)N2C[C@@H](C)NC[C@@H]2C)c1.Fc1cccc(CBr)c1>>CCN(CC)C(=O)c1cccc([C@H](c2cccc(OC)c2)N2C[C@@H](C)N(Cc3cccc(F)c3)C[C@@H]2C)c1,,CC#N,,[I-].[Na+],,test
US20120135999A1,Cc1cc2[nH]ccc2c[n+]1[O-]>>Cc1cc2[nH]ccc2cn1,[Fe],CC(=O)O,,,,test
US20100130738A1,CI.COC(=O)C(C)C(=O)c1ccc(OC)c2ncccc12>>COC(=O)C(C)(C)C(=O)c1ccc(OC)c2ncccc12,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US05585390,Cc1cc(C)nc(N(CC(=O)NCC(N)=O)C(=O)OCc2ccccc2)c1>>Cc1cc(C)nc(NC(=O)CN)c1,[Pd],,,CO,,test
US20100056511A1,Nc1ccc(N2CCS(=O)(=O)CC2)cc1.O=C(Cl)C(=O)c1c(-c2ccccc2)cc2ccccn12>>O=C(Nc1ccc(N2CCS(=O)(=O)CC2)cc1)C(=O)c1c(-c2ccccc2)cc2ccccn12,,C1CCOC1,,CCN(CC)CC,,test
US05238932,Br.N[C@H](Cc1ccccc1)C(=O)O>>O=C(O)[C@H](Br)Cc1ccccc1,,O,,O=N[O-].[Na+],,test
US20060160879A1,CCOC(=O)c1c(N)c2ccc(Br)cc2n1Cc1cccc(Cl)c1.O=C(Cl)c1ccc(Cl)cc1>>CCOC(=O)c1c(NC(=O)c2ccc(Cl)cc2)c2ccc(Br)cc2n1Cc1cccc(Cl)c1,CN(C)c1ccncc1,O,,CC#N,CCN(CC)CC,test
US04874771,C=CS(=O)(=O)F.Nc1ccc(Cl)c(Cl)c1>>O=S(=O)(F)CCNc1ccc(Cl)c(Cl)c1,,O,,CN(C)C=O,,test
US20090281087A1,CN1CCC(CO)CC1.O=C(Oc1ccc([N+](=O)[O-])cc1)Oc1ccc([N+](=O)[O-])cc1>>CN1CCC(COC(=O)Oc2ccc([N+](=O)[O-])cc2)CC1,,ClCCl,,CN1CCOCC1,,test
US04226860,CC1(C)OCCc2c1[nH]c1ccccc21.ClCc1ccccc1>>CC1(C)OCCc2c1n(Cc1ccccc1)c1ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20100121048A1,NC1Cc2ccccc2C1.[C-]#[N+]C(C(=O)OC)=C(Br)c1ccccc1>>COC(=O)c1ncn(C2Cc3ccccc3C2)c1-c1ccccc1,,CN(C)C=O,O,CCN(CC)CC,Cl,test
US20040023961A1,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCc3ccncc3)c3ccccc23)cc1.NNc1cccc(C(F)(F)F)c1>>CC(C)(C)c1cc(NC(=O)Nc2ccc(OCc3ccncc3)c3ccccc23)n(-c2cccc(C(F)(F)F)c2)n1,,CCCCCC,CCOC(C)=O,,,test
US20080139505A1,CN(C)C=O.N#Cc1cc(Cl)ccc1F>>N#Cc1cc(C=O)ccc1F,II,C1CCOC1,,[Mg],,test
US20050124605A1,O=C(Cl)c1ccccc1.c1ccc(C2=NCCNc3ccccc32)cc1>>O=C(c1ccccc1)N1CCN=C(c2ccccc2)c2ccccc21,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20110044899A1,CCOC(=O)c1cnc2cc(I)ccc2n1>>O=C(O)c1cnc2cc(I)ccc2n1,,CC(=O)O,,CCO,[Na+].[OH-],test
US20080096921A1,C=CC(=O)OC.O=Cc1ccc(Br)cc1>>C=C(C(=O)OC)C(O)c1ccc(Br)cc1,,CO,,C1CN2CCN1CC2,,test
US20020094938A1,CC(N)CC(=O)C1C(C)C=CCC1(C)C.O=C(O)C=Cc1ccc(O)cc1O>>C=CC(C)(CCC=C(C)C)OC(=O)C=Cc1ccc(O)cc1O,,C1CCOC1,CN(C)C=O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20120157439A1,BrCc1ccccc1.CCCS(=O)(=O)Nc1ccc(F)c(N)c1F>>CCCS(=O)(=O)N(Cc1ccccc1)c1ccc(F)c(N)c1F,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20130178460A1,CN(CCNc1ncc2scc(C(=O)Nc3cccc4c3ncn4C)c2n1)C(=O)OC(C)(C)C.Cl>>CNCCNc1ncc2scc(C(=O)Nc3cccc4c3ncn4C)c2n1.Cl,,C1COCCO1,,,,test
US20040122002A1,CS(=O)(=O)c1ccc(C=O)cc1.C[N+](=O)[O-]>>CS(=O)(=O)c1ccc(C=C[N+](=O)[O-])cc1,,CO,,Cl,[Na+].[OH-],test
US20150246923A1,N#CCC(=O)C1CC1.NNCCO>>Nc1cc(C2CC2)nn1CCO,,CCO,,,,test
US20020161237A1,COC(=O)/C(=C/c1cnc2ccccc2c1)NC(=O)c1ccc(C(O)CCc2cccc(O)c2)cc1Cl>>O=C(O)/C(=C/c1cnc2ccccc2c1)NC(=O)c1ccc(C(O)CCc2cccc(O)c2)cc1Cl,,C1CCOC1,CO,[Na+].[OH-],,test
US20050277661A1,CCO/C=C/c1c(C(=O)OCC)ncc2c1ccn2Cc1ccc(F)cc1.NO>>CCO/C=C/c1c(C(=O)NO)ncc2c1ccn2Cc1ccc(F)cc1,,CO,,Cl,[Na+].[OH-],test
US20120083475A1,CC1(C)OC(=O)C2(CC2)C(=O)O1.CCc1cccc(N)c1>>CCc1cccc(N2CCC(C(=O)O)C2=O)c1,,CCO,,,,test
US05948775,COc1ccc2c(=O)[nH]c(=O)oc2c1.Nc1ccc(OCCCl)cc1>>COc1ccc(C(=O)Nc2ccc(OCCCl)cc2)c(N)c1,CN(C)c1ccncc1,,,CCO,,test
US05153210,CC(=O)Cc1ccc(O)cc1.COC(=O)c1ccc([N+](=O)[O-])o1>>COC(=O)c1ccc(Oc2ccc(CC(C)=O)cc2)o1,,CS(C)=O,,[H-].[Na+],,test
US06511974B1,O=C(Cl)c1ccc(-n2ccnc2)cc1.c1ccc2c(c1)Cn1cccc1CN2>>O=C(c1ccc(-n2ccnc2)cc1)N1Cc2cccn2Cc2ccccc21,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20140163001A1,CCOC(=O)CC(=O)CCl.NC(=S)c1cnn(C2CCCCC2)c1-c1ccc(F)cc1>>CCOC(=O)Cc1csc(-c2cnn(C3CCCCC3)c2-c2ccc(F)cc2)n1,,CCO,,,,test
US05214037,C=[N+]=[N-].COc1ccc(CSc2nc[nH]n2)cc1>>COc1ccc(CSc2ncnn2C)cc1,,CCOCC,CO,,,test
US20100113502A1,CC1CCN(C(=O)c2ccc3[nH]c4c(c3c2)CN(C(=O)OC(C)(C)C)CC4)CC1.CI>>CC1CCN(C(=O)c2ccc3c(c2)c2c(n3C)CCN(C(=O)OC(C)(C)C)C2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20110092485A1,CCCN(CCC)C(=O)C1=Cc2ccc(Br)cc2N=C(N)C1.CCOC(C)=O.COC(=O)c1ccc(B(O)O)cc1.c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCN(CCC)C(=O)C1=Cc2ccc(-c3cccc(CC(=O)OCC)c3)cc2N=C(N)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20040102509A1,C1CCNCC1.C=O.O=C1Nc2ccccc2/C1=C/c1ccc[nH]1>>O=C1C(=Cc2ccc[nH]2)c2ccccc2N1CN1CCCCC1,,CCO,,,,test
US06350749B1,Cl.N=C(N)NN.O=C1CC(c2ccccc2Cl)Cc2[nH]nc(Nc3ccccc3)c21>>Cl.N=C(N)NN=C1CC(c2ccccc2Cl)Cc2[nH]nc(Nc3ccccc3)c21,,CCO,,Cl,O,test
US20040186301A1,O=[PH](O)CCCCc1ccccc1.OCc1ccccc1>>O=[PH](CCCCc1ccccc1)OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US06087390,CC(C)C1=CC2CC3(C=O)C4CCC(C)C4CC2(COC24OC5OC(C(O)C5O2)C4O)C13C(=O)O.CCCCCC(=O)OC(=O)CCCCC>>CCCCCC(=O)OC1C2OC3(OCC45CC6C(C)CCC6C6(C=O)CC4C=C(C(C)C)C65C(=O)O)OC2OC1C3O,,c1ccncc1,,,,test
US20040023964A1,CC(C)(O)c1cnn2c(-c3ccc(F)c(-c4ncncc4C(N)=O)c3)cnc2n1>>CC(C)(O)c1cnn2c(-c3ccc(F)c(-c4ncncc4C#N)c3)cnc2n1,,Cc1ccccc1,,CCCC[Sn](=O)CCCC,,test
US20140206700A1,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.CC(C)(C)c1nnc(-c2nc(/C(N)=N/N)cnc2N)o1>>CC(C)(C)OC(=O)N1CCC(C(=O)N/N=C(\N)c2cnc(N)c(-c3nnc(C(C)(C)C)o3)n2)CC1,,CC(=O)N(C)C,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05665718,CCNCC.O=C1c2ccccc2-n2cnc(-c3noc(CCl)n3)c2[C@@H]2CCN12>>CCN(CC)Cc1nc(-c2ncn3c2[C@@H]2CCN2C(=O)c2ccccc2-3)no1,,CN(C)C=O,,,,test
US07074801B1,Nc1cc(Br)ccc1F.O=C(c1ccccc1)c1ccccc1>>Fc1ccc(Br)cc1N=C(c1ccccc1)c1ccccc1,,CCOC(C)=O,Cc1ccccc1,Cc1ccc(S(=O)(=O)O)cc1,,test
US20040235875A1,CSc1nccc(C(=O)/C=C/N(C)C)n1.NN>>CSc1nccc(-c2ccn[nH]2)n1,,CCO,,Cl,,test
US05763621,C=C(C(=O)O)C(CC(C)C)C(=O)NC(C(=O)NC1CC1)C(C)(C)C.Sc1cccs1>>CC(C)CC(C(=O)NC(C(=O)NC1CC1)C(C)(C)C)C(CSc1cccs1)C(=O)O,,CO,,CCOCC,,test
US20110245232A1,Nc1ccccc1.O=C(O)c1cnccc1Cl>>O=C(O)c1cnccc1Nc1ccccc1,,CC#N,,,,test
US20020013310A1,Br.OCc1ccc2c(Cl)ccnc2c1>>Clc1ccnc2cc(CBr)ccc12,,O,,CCOC(C)=O,O=C([O-])O.[Na+],test
US20040048908A1,CCOC(=O)c1conc1-c1ccc(C(F)(F)F)cc1>>OCc1conc1-c1ccc(C(F)(F)F)cc1,,C1CCOC1,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US04153716,BrBr.OCCc1ccc2occ(-c3ccccc3)c2c1>>OCCc1ccc2oc(Br)c(-c3ccccc3)c2c1,,ClCCl,,,,test
US20140378431A1,Nc1ccc(F)cc1.O=[N+]([O-])c1cnc(Cl)nc1Cl>>O=[N+]([O-])c1cnc(Cl)nc1Nc1ccc(F)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20130102778A1,Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)O)cn1.Cn1cc(N)cn1>>Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)Nc2cnn(C)c2)cn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20100267561A1,Cc1cc(-c2ccc(Cl)cc2)nn1-c1cnn(C)c(=O)c1-n1nc(-c2ccc(Cl)cc2)cc1C.O>>CC1=CC(c2ccc(Cl)cc2)(c2c(O)cnn(C)c2=O)NN1,,O,,CO,[Na+].[OH-],test
US05286728,Clc1ccc(CCN2CCNCC2)cc1.O=C(CCl)Nc1ccc(C(=O)Cl)cc1>>O=C(CCl)Nc1ccc(C(=O)N2CCN(CCc3ccc(Cl)cc3)CC2)cc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US04880894,Cc1nc2ccccc2s1.O=Cc1ccccc1>>C(=Cc1nc2ccccc2s1)c1ccccc1,,O,,Cc1ccccc1,[Na+].[OH-],test
US06069176,CC(C)=O.COc1ccc(C=O)cc1OC>>COc1ccc(C=CC(C)=O)cc1OC,,CC(C)=O,,C1CCNCC1,CC(=O)O,test
US20100244009A1,O=[N+]([O-])c1cc(-c2ccccc2)ccc1-c1ccc(-c2ccccc2)cc1[N+](=O)[O-]>>Nc1cc(-c2ccccc2)ccc1-c1ccc(-c2ccccc2)cc1N,[Pd],CO,,Cl,[BH4-].[Na+],test
US20050171118A1,CC(C)[Si](C(C)C)(C(C)C)n1ccc2cc(N3CCN(C(=O)OC(C)(C)C)CC3)ccc21>>CC(C)(C)OC(=O)N1CCN(c2ccc3[nH]ccc3c2)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140235660A1,COc1ccc(-c2sc3cc(OC)ccc3c2Oc2ccc(/C=C/C(=O)O)cc2)cc1.[NH4+]>>COc1ccc(-c2sc3cc(OC)ccc3c2Oc2ccc(/C=C/C(N)=O)cc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06251887B1,CCOC(C)O[C@H]1CC[C@]2(C)C3=C(CC[C@H]2C1(C)C)C1=CC[C@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)[C@@]1(C)CC3>>CCOC(C)O[C@H]1CC[C@]2(C)C3=C(CC[C@H]2C1(C)C)C1=CC[C@H]([C@@H](C)O)[C@@]1(C)CC3,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20150291595A1,COc1ccc(C(N)=O)cc1N.O=C(Cl)c1c(Cl)ncnc1Cl>>COc1ccc(C(N)=O)cc1NC(=O)c1c(Cl)ncnc1Cl,,ClCCl,,,,test
US20030007927A1,CC(C)(C)OC(=O)N[C@@H](CC(=O)ON1C(=O)CCC1=O)C(=O)OCc1ccccc1.NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>CC(C)(C)OC(=O)NC(CC(=O)NCC(O)C(O)C(O)C(O)CO)C(=O)OCc1ccccc1,,C1CCOC1,O,CCN(CC)CC,,test
US20160090374A1,CC(=O)N[C@H]1CCN(c2nc(Cl)nc3c2CCCC3)C1.Nc1ccc(N)c([N+](=O)[O-])c1>>CC(=O)N[C@H]1CCN(c2nc(Nc3ccc(N)c([N+](=O)[O-])c3)nc3c2CCCC3)C1.Cl,,CCCCO,,,,test
US20070244132A1,Nc1ccc(OCc2cccc(F)c2)c(Cl)c1.OCc1ccc(Cn2ccc3ncnc(Cl)c32)cc1>>OCc1ccc(Cn2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c32)cc1,,CCOC(C)=O,CN1CCCC1=O,,,test
US20010006969A1,CC(C)(C)N.CCc1csc2c(Cl)nc(Cl)nc12>>CCc1csc2c(NC(C)(C)C)nc(Cl)nc12,,CN(C)C=O,,,,test
US20060194969A1,CCOC(=O)c1cc(NCc2c(C)cccc2CC)c2nc(C)n(C)c2c1.NCCO>>CCc1cccc(C)c1CNc1cc(C(=O)NCCO)cc2c1nc(C)n2C,,[Cl-],[NH4+],,,test
US20060009453A1,CN(C)CCN.CNc1nccc(-c2cccnc2Oc2ccc(NC(=O)c3cccc(C=O)c3)cc2C)n1>>CNc1nccc(-c2cccnc2Oc2ccc(NC(=O)c3cccc(CNCCN(C)C)c3)cc2C)n1,,CO,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20120010397A1,Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)[C@H]1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)[C@H]1OS(=O)(=O)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US20030073675A1,C[C@]12C[C@H](c3ccc(CCCO)cc3)C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CCC2=O.O=C1CCC(=O)N1Cl>>C[C@@]12CCC[C@H]1[C@@H]1CCC3=C(Cl)C(=O)CCC3=C1[C@@H](c1ccc(CCCO)cc1)C2,,CN(C)C=O,,O,,test
US20100267666A1,CC1(C(=O)c2cn(COCC[Si](C)(C)C)c3ncc(-c4cccc(NC5CCCC5)c4)nc23)CCCCC1.CI>>CN(c1cccc(-c2cnc3c(n2)c(C(=O)C2(C)CCCCC2)cn3COCC[Si](C)(C)C)c1)C1CCCC1,,CN(C)C=O,,[H-].[Na+],,test
US20110224191A1,CC(c1c(Cl)ccc(F)c1Cl)c1c[nH]c2ncc(C3=CCNCC3)cc12.O=CO>>CC(c1c(Cl)ccc(F)c1Cl)c1c[nH]c2ncc(C3=CCN(C=O)CC3)cc12,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20080045493A1,C=Cc1ccc([N+](=O)[O-])c(F)c1.COCN(Cc1ccccc1)C[Si](C)(C)C>>O=[N+]([O-])c1ccc(C2CCN(Cc3ccccc3)C2)cc1F,,CCOC(C)=O,ClCCl,O=C(O)C(F)(F)F,,test
US20110136823A1,O=C=Nc1ccccc1.c1csc(-c2noc(C3CC[NH2+]CC3)n2)c1>>O=C(Nc1ccccc1)N1CCC(c2nc(-c3cccs3)no2)CC1,,c1ccncc1,,Cl,,test
US20130345246A1,CC(C)(C)S(=O)N=C1c2cc(OCCCF)ccc2CC12CCC(O)CC2>>N=C1c2cc(OCCCF)ccc2CC12CCC(O)CC2,,C1COCCO1,,Cl,,test
US20030236287A1,CCOC(=O)C(=O)CC(=O)C1CC1.NO>>CCOC(=O)c1cc(C2CC2)on1,,CCO,,Cl,,test
US20100173955A1,COC(=O)Cc1ccc(Oc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(CN)c1.O=S(=O)(Cl)c1ccc(F)cc1>>COC(=O)Cc1ccc(Oc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(CNS(=O)(=O)c2ccc(F)cc2)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20010039285A1,COc1ccc(C(=O)CBr)cc1.NCc1ccccc1>>COc1ccc(C(=O)CNCc2ccccc2)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20120108627A1,CC(C)(C#N)c1ccc(-n2c(=O)[nH]c3cnc4ccc(Br)cc4c32)cc1.O=C=NCc1ccccc1>>CC(C)(C#N)c1ccc(-n2c(=O)n(C(=O)NCc3ccccc3)c3cnc4ccc(Br)cc4c32)cc1,,ClCCl,,CCN(CC)CC,O,test
US20150197522A1,CCOC(=O)Cn1c2ccccc2c2nnc(SC(CC)C(=O)N3c4ccccc4Sc4ccccc43)nc21>>CCC(Sc1nnc2c3ccccc3n(CC(=O)O)c2n1)C(=O)N1c2ccccc2Sc2ccccc21,,C1COCCO1,,[Na+].[OH-],,test
US20140018313A1,CC#N.CC(C)(C)OC(=O)N1C2CC[C@@H](C2)C1C(=O)O.CCN(C(C)C)C(C)C.O=C(CBr)c1ccc2c(c1)CCc1cc(Br)ccc1-2>>CC(C)(C)OC(=O)N1[C@@H]2CC[C@@H](C2)[C@H]1c1ncc(-c2ccc3c(c2)CCc2cc(Br)ccc2-3)[nH]1,,CCOC(C)=O,,,,test
US08815877B2,C[Si](C)(C)CCOCn1ccc2c(C#N)cncc21>>C[Si](C)(C)CCOCn1ccc2c(CN)cncc21,[Ni],CO,N,,,test
US20070072925A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.CCCC#CO>>C#CCCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,ClCCl,,CCN(CC)CC,O=C([O-])[O-].[K+].[K+],test
US20060089360A1,FC(F)(F)c1ccc(Nc2cc(Cl)ncn2)cc1.OB(O)c1ccc2nccnc2c1>>FC(F)(F)c1ccc(Nc2cc(-c3ccc4nccnc4c3)ncn2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20060173018A1,O=C(NC[C@@H]1CCN(c2nc(-c3ccccc3O)nc3ccc(F)cc23)C1)OCc1ccccc1>>NC[C@@H]1CCN(c2nc(-c3ccccc3O)nc3ccc(F)cc23)C1,[Pd],CO,,,,test
US20050245514A1,CCC(O[Si](CC)(CC)CC)C(C)C1OC1CC(C)(/C=C/C=C(\C)C1OC(=O)CC(O[Si](CC)(CC)CC)CCC(C)C(OC(C)=O)C=CC1C)O[Si](CC)(CC)CC>>CCC(O[Si](CC)(CC)CC)C(C)C1OC1CC(C)(/C=C/C=C(\C)C1OC(=O)CC(O[Si](CC)(CC)CC)CCC(C)C(O)C=CC1C)O[Si](CC)(CC)CC,,CCOC(C)=O,CO,O=C([O-])[O-].[K+].[K+],,test
US20060223826A1,O=[N+]([O-])c1cc(C2OCCO2)ccc1OS(=O)(=O)C(F)(F)F.OB(O)c1cccs1>>O=[N+]([O-])c1cc(C2OCCO2)ccc1-c1cccs1,,COCCOC,O,O=C([O-])O.[Na+],,test
US20130331378A1,N=C(NO)c1cccc(Cc2c(-c3ccccc3)nn3cc(Cl)ccc23)n1.O.S=C(n1ccnc1)n1ccnc1>>O=c1[nH]c(-c2cccc(Cc3c(-c4ccccc4)nn4cc(Cl)ccc34)n2)ns1,,O,,C1CCOC1,Cl,test
US20080070896A1,CC(C)(CO)C(=O)O.NCCNS(=O)(=O)c1ccccc1[N+](=O)[O-]>>CC(C)(CO)C(=O)NCCNS(=O)(=O)c1ccccc1[N+](=O)[O-],,CN(C)C=O,ClCCl,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20100152230A1,CC(C)(O)CN.CCCCCc1cc(Cl)c([N+](=O)[O-])c(Cl)n1>>CCCCCc1cc(NCC(C)(C)O)c([N+](=O)[O-])c(Cl)n1,,CN(C)C=O,,CCN(CC)CC,,test
US04219657,CCOC(=O)CC1CCC(=O)C(Br)C1.Sc1cccc(Cl)c1>>CCOC(=O)CC1CCC(=O)C(Sc2cccc(Cl)c2)C1,,CCO,,[K+].[OH-],,test
US05376681,CC(C)C(=O)c1ccccc1.COc1c(C)c(C)cc(C)c1Br>>COc1c(C)c(C)cc(C)c1C(O)(c1ccccc1)C(C)C,,C1CCOC1,O,[Li]CCCC,,test
US20090298815A1,C=CCOC(=O)Nc1cc(C(=O)OC)ccc1F.Cc1ccnc(Cl)n1>>C=CCOC(=O)Nc1cc(C(=O)Cc2ccnc(Cl)n2)ccc1F,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20100168145A1,CCOC(=O)C1(c2ccc(OC)cc2OC)CCCC(=O)N1>>COc1ccc(C2(CO)CCCC(=O)N2)c(OC)c1,,CO,,[BH4-].[Na+],,test
US20130252941A1,N#Cc1cccc(F)c1/N=C/c1cncc(F)c1N=[N+]=[N-]>>N#Cc1cccc(F)c1-n1cc2cncc(F)c2n1,,Cc1ccccc1,,,,test
US20150353497A1,CN1CC=C(c2ccc3c(C(=O)NCC4CCC(F)(F)CC4)c(Cl)ccc3n2)CC1>>CN1CCC(c2ccc3c(C(=O)NCC4CCC(F)(F)CC4)c(Cl)ccc3n2)CC1,[Pd],,,CC[SiH](CC)CC,,test
US20140018393A1,O=C(N(CC1CCNCC1)[C@@H]1C[C@H]1c1ccc(I)cc1)C(F)(F)F.O=Cc1ccccc1>>O=C(N(CC1CCN(Cc2ccccc2)CC1)[C@@H]1C[C@H]1c1ccc(I)cc1)C(F)(F)F,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05726306,COc1ccccc1C(=O)c1cc(Cl)ccc1N>>Nc1ccc(Cl)cc1C(=O)c1ccccc1O,,Br,,O=C([O-])O.[Na+],,test
US20110028445A1,CC1(C)[C@H]2Cc3cc([N+](=O)[O-])c([N+](=O)[O-])cc3[C@]1(C)CCN2C(=O)C(F)(F)F>>CC1(C)[C@H]2Cc3cc(N)c(N)cc3[C@]1(C)CCN2C(=O)C(F)(F)F,[Pd],CO,,,,test
US04544652,CCCCO.O=[PH](O)C(O)CCl>>CCCCO[PH](=O)C(O)CCl,,c1ccccc1,,O,,test
US20140073627A1,CNCCc1ccc(C2=NCCN2)cc1.COC(=O)c1nnc(CN(C)S(=O)(=O)c2c(C)cc(OC)cc2C)s1>>COc1cc(C)c(S(=O)(=O)N(C)Cc2nnc(C(=O)N(C)CCc3ccc(C4=NCCN4)cc3)s2)c(C)c1,,ClCCl,,C[Al](C)C,,test
US20110230459A1,O=C(O)CN1CCCC(c2ccc(F)cc2)(c2ccc(F)cc2)C1=O.O=C(OCc1ccccc1)N1CCNCC1>>O=C(CN1CCCC(c2ccc(F)cc2)(c2ccc(F)cc2)C1=O)N1CCN(C(=O)OCc2ccccc2)CC1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20050043388A1,NNC(=O)c1ccc(NC(=O)CCc2ccc3c(c2)OCO3)cc1.O=C1Nc2ccc(I)cc2C1=O>>O=C(CCc1ccc2c(c1)OCO2)Nc1ccc(C(=O)NN=C2C(=O)Nc3ccc(I)cc32)cc1,,CC(=O)O,,,,test
US20160159752A1,COC(=O)N[C@H](C(=O)Nc1cccc(F)c1CC[C@H]1CN(C(=O)OC(C)(C)C)C[C@H](C)N1S(=O)(=O)C1CC1)[C@@H](c1ccc(Cl)cc1)C1CCOCC1>>COC(=O)N[C@H](C(=O)Nc1cccc(F)c1CC[C@H]1CNC[C@H](C)N1S(=O)(=O)C1CC1)[C@@H](c1ccc(Cl)cc1)C1CCOCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160176864A1,COC(=O)c1ccc2c(c1)[nH]c1cc(-c3c(C)noc3C)cnc12.CS(=O)(=O)OC(c1ccncc1F)C1CCOCC1>>COC(=O)c1ccc2c3ncc(-c4c(C)noc4C)cc3n(C(c3ccncc3F)C3CCOCC3)c2c1,,CC#N,O,O=C(O)C(F)(F)F,,test
US08084466B2,O=C1CCC(=O)N1Cl.O=Cc1ccc2[nH]ccc2c1>>O=Cc1ccc2[nH]cc(Cl)c2c1,,ClCCl,,,,test
US20090076086A1,NCC1CCCCC1.O=C(O)c1cccnc1SCCS(=O)(=O)c1ccccc1>>O=C(NCC1CCCCC1)c1cccnc1SCCS(=O)(=O)c1ccccc1,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20040102450A1,C1CCOC1.CCOC(=O)N=NC(=O)OCC.COc1ccc(CN(C[C@H](C)O)C(=O)[C@H](C)NC(=O)C(F)(F)F)c(OC)c1.O=P(Oc1ccccc1)(Oc1ccccc1)Oc1ccccc1>>COc1ccc(CN2C[C@@H](C)N(C(=O)C(F)(F)F)[C@@H](C)C2=O)c(OC)c1.COc1ccc(CN2C[C@@H](C)N(C(=O)OCc3ccccc3)[C@@H](C)C2=O)c(OC)c1,,C1CCOC1,,,,test
US05254697,C=CC(O)CC1CCCCC1.O=S(Cl)Cl>>ClC/C=C/CC1CCCCC1,,CCOCC,,O,,test
US20150210688A1,COC(=O)c1ccc(C)c(-c2[nH]c(C3CCC(OC)CC3)nc2C)c1>>COC1CCC(c2nc(C)c(-c3cc(C(=O)O)ccc3C)[nH]2)CC1,,CO,O,[Na+].[OH-],,test
US20150119373A1,CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC[C@@H]2[C@H]4[C@H](C5(C)CC5)CC[C@]4(C(=O)Cl)CC[C@]23C)C1(C)C.CCN1CCNCC1>>CCN1CCN(C(=O)[C@]23CC[C@@H](C4(C)CC4)[C@@H]2[C@H]2CC[C@H]4[C@@](C)(CC[C@H]5C(C)(C)[C@@H](OC(C)=O)CC[C@@]54C)[C@]2(C)CC3)CC1,,ClCCl,,CCN(CC)CC,,test
US20050075327A1,C[C@H](OC(=O)Oc1ccc([N+](=O)[O-])cc1)C(=O)N[C@@H]1C(=O)N(CC2CC2)c2ccccc2-c2ccccc21.NCC(F)(F)C(F)(F)F>>C[C@H](OC(=O)NCC(F)(F)C(F)(F)F)C(=O)N[C@@H]1C(=O)N(CC2CC2)c2ccccc2-c2ccccc21,,CCOC(C)=O,ClCCl,,,test
US20060111360A1,CC(C)C(=O)Cl.CN1CCN(CCCN(C(=O)Nc2ccc(F)c(Cl)c2)C2CCc3ccc(N)cc3C2)CC1>>CC(C)C(=O)Nc1ccc2c(c1)CC(N(CCCN1CCN(C)CC1)C(=O)Nc1ccc(F)c(Cl)c1)CC2,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160244437A1,Cc1cc(C(=O)NC2CCC(N(C)C)CC2)ccc1-c1cccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nnn[nH]3)c(F)c2)c1.Cl>>Cc1cc(C(=O)NC2CCC(N(C)C)CC2)ccc1-c1cccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3nnn[nH]3)c(F)c2)c1.Cl,,C1COCCO1,ClCCl,,,test
US20080312192A1,Nc1ccc(N2CCC(N3CCCCC3)CC2)c(C(F)(F)F)c1.O=C=Nc1ccc(Oc2cc(Cl)ncn2)cc1>>O=C(Nc1ccc(Oc2cc(Cl)ncn2)cc1)Nc1ccc(N2CCC(N3CCCCC3)CC2)c(C(F)(F)F)c1,,C1CCOC1,,,,test
US20080171755A1,COC(OC)c1ccnc(C)n1.Nc1ccccc1.[O-]P(Oc1ccccc1)Oc1ccccc1>>Cc1nccc(C(Nc2ccccc2)P(=O)(Oc2ccccc2)Oc2ccccc2)n1,,O,,Br,,test
US20100113782A1,CCOC(=O)C1CCNCC1.O=C(Nc1ccc(I)c(Cl)c1)c1ccc(Cl)nc1>>CCOC(=O)C1CCN(c2ccc(C(=O)Nc3ccc(I)c(Cl)c3)cn2)CC1,CN(C)c1ccncc1,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US04256640,C#CCBr.S=C1Cc2ccccc2N1>>C#CCSc1cc2ccccc2[nH]1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150284395A1,C#CCN.O=C(O)c1cnn2c(=O)cc(-c3ccc4[nH]nnc4c3)[nH]c12>>C#CCNC(=O)c1cnn2c(=O)cc(-c3ccc4[nH]nnc4c3)[nH]c12,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20030220196A1,BrBr.O=C1COc2ccc(F)cc2N1>>O=C1COc2cc(Br)c(F)cc2N1,,ClCCl,,,,test
US20130059834A1,CC(C)(C)NC(=O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ncc(-c3n[nH]c4ccc(OC(F)F)cc34)nc12.CC(C)(CCCCl)[N+](=O)[O-]>>CC(C)(C)NC(=O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ncc(-c3nn(CCCC(C)(C)[N+](=O)[O-])c4ccc(OC(F)F)cc34)nc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080021081A1,CC(C)O.Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1.N#Cc1ccc(B(O)O)cc1>>N#Cc1ccc(-c2ccc([C@@H]3C[C@H]3CCO)cc2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070225267A1,CC(=O)OC(C)=O.C[C@H]1[C@H](OCC(C)(C)C)OC[C@H]([C@@H](O)[C@@H](N)Cc2cccc(O)c2)N1C(=O)OC(C)(C)C>>CC(=O)N[C@@H](Cc1cccc(O)c1)[C@H](O)C1CO[C@@H](OCC(C)(C)C)[C@H](C)N1C(=O)OC(C)(C)C,,CCOC(C)=O,,CCN(C(C)C)C(C)C,,test
US20050107616A1,CCCC[C@H](NC(=O)O[C@@H](Cc1nnc(-c2ccc(F)cc2)o1)C(C)(C)C)C(=O)C(C#N)=P(c1ccccc1)(c1ccccc1)c1ccccc1.NCc1ccncc1.O=[O+][O-]>>CCCC[C@H](NC(=O)O[C@H](Cc1nnc(-c2ccc(F)cc2)o1)C(C)(C)C)C(=O)C(=O)NCc1ccncc1,,ClCCl,,,,test
US20040072880A1,CCN.Clc1nc(NCC2(c3ccccc3)CCCCC2)c2ccccc2n1>>CCNc1nc(NCC2(c3ccccc3)CCCCC2)c2ccccc2n1,,C1CCOC1,,,,test
US20140288123A1,CCOC(=O)c1c(C)[nH]c2ccccc12.C[Al](C)C>>CCOC(=O)c1c(C)cncc1C,,C1COCCO1,,,,test
US20130158031A1,C(#Cc1ccc2ccccc2n1)c1ccc(-c2n[nH]cc2-c2ccncc2)cc1.CCBr>>CCn1cc(-c2ccncc2)c(-c2ccc(C#Cc3ccc4ccccc4n3)cc2)n1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US07855292B2,Nc1cc(Cl)c(Cl)cc1C(=O)O.O=C(Cl)Cl>>O=c1[nH]c2c(Cl)c(Cl)ccc2c(=O)o1,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,O,test
US20050020574A1,Nc1ccnc(Cl)c1[N+](=O)[O-].O>>Nc1ccnc(O)c1[N+](=O)[O-],,O,,CS(C)=O,,test
US20050245529A1,ClC/C=C/c1ccc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)cc1.NC1CCCC1>>Clc1ccc(-c2ccc(C#Cc3ccc(/C=C/CNC4CCCC4)cc3)nc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20100240698A1,C=CC1CC1(NC(=O)C1CC(Oc2cc(-c3nc(C(C)C)cs3)nc3c(Cl)c(OC)ccc23)CN1)C(=O)OCC.C=CCCCCCC(C)(C)C(=O)O>>C=CCCCCCC(C)(C)C(=O)N1CC(Oc2cc(-c3nc(C(C)C)cs3)nc3c(Cl)c(OC)ccc23)CC1C(=O)NC1(C(=O)OCC)CC1C=C,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20060287300A1,CC(C)CCC1(O)C(=O)CC(=O)c2ccccc21.CO>>COC1=CC(=O)C(O)(CCC(C)C)c2ccccc21,,CO,,CCOCC,FB(F)F,test
US20120108583A1,CC1(C)Cc2c(c(C(=O)O)cc3nc(Nc4c(Cl)cccc4Cl)[nH]c23)O1.Cc1ccc(N)c(F)c1>>Cc1ccc(NC(=O)c2cc3nc(Nc4c(Cl)cccc4Cl)[nH]c3c3c2OC(C)(C)C3)c(F)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,O=S(Cl)Cl,test
US20130217699A1,CC(=O)O.CC(O)C(=O)O>>CC(=O)OC(C)C(=O)O,,Cc1ccccc1,,O=S(=O)(O)O,,test
US20110237579A1,CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)NC1CCC(=O)CC1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)NC1CC=C(OS(=O)(=O)C(F)(F)F)CC1,,ClCCl,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20150111870A1,CO.FC(F)(F)Cc1c(Cl)nc2ccc(Br)cc2c1Cl>>COc1c(CC(F)(F)F)c(Cl)nc2ccc(Br)cc12,,CO,,C[O-].[Na+],,test
US20090298878A1,CI.N#Cc1cccc(C(CO)ON=C2CCN(S(=O)(=O)c3ccc(OC(F)(F)F)cc3)CC2)c1>>COCC(ON=C1CCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)CC1)c1cccc(C#N)c1,,C1CCOC1,,[H-].[Na+],,test
US05296603,COC(=O)c1sc2c(c1N)CN(C(C)=O)CC2.Cl>>COC(=O)c1sc2c(c1N)CNCC2.Cl,,CO,,,,test
US20090291978A1,CCOC(=O)c1cc2ccc(CO)cc2s1>>O=C(O)c1cc2ccc(CO)cc2s1,,C1CCOC1,,O,[Li+].[OH-],test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Nc1cccc(O)c1>>COc1ccc2nc(Nc3cccc(O)c3)c3[nH]ncc3c2c1,C1COCCO1,CO,,Cl,,test
US04837242,CC1CC(C)(C)c2cccc(N)c21.Cc1nc(Cl)sc1C(=O)O>>Cc1nc(Cl)sc1C(=O)Nc1cccc2c1C(C)CC2(C)C,,ClCCl,,O,,test
US20130087772A1,C=C[Sn](CCCC)(CCCC)CCCC.CC(C)(C)c1ccc(-c2nnc(-c3ccc(Br)cc3)o2)cc1>>C=Cc1ccc(-c2nnc(-c3ccc(C(C)(C)C)cc3)o2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20080090840A1,CCCCc1ccc(-c2ccc(COc3ccc([C@H](CC(=O)N4C(=O)OC[C@@H]4Cc4ccccc4)c4ccon4)cc3)s2)cc1.OO>>CCCCc1ccc(-c2ccc(COc3ccc([C@H](CC(=O)O)c4ccon4)cc3)s2)cc1,,C1CCOC1,,Cl,[Li+].[OH-],test
US20140275111A1,CCOC(=O)C(C)(C)Cc1ccc(NC(=O)Cc2ccc(-c3cnc(OCc4ccccc4)cc3OCC)cc2F)cc1C(F)(F)F>>CCOc1cc(OCc2ccccc2)ncc1-c1ccc(CC(=O)Nc2ccc(CC(C)(C)CO)c(C(F)(F)F)c2)c(F)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20160200725A1,CC(C)(C)OC(=O)N1CCN(CC2(CO)CC2)CC1.II>>CC(C)(C)OC(=O)N1CCN(CC2(CI)CC2)CC1,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060264435A1,CC(=O)Cc1cc(Cl)ccc1OCc1ccccc1.COC(OC)N(C)C>>CC(=O)/C(=C\N(C)C)c1cc(Cl)ccc1OCc1ccccc1,,Cc1ccccc1,,,,test
US04252809,CN(C)CCOc1ccc(CC#N)cc1.Nc1nc(N)c(N=O)c(N)n1>>CN(C)CCOc1ccc(-c2nc3c(N)nc(N)nc3nc2N)cc1,,CCOCCO,,Cl,[Na],test
US20020133007A1,CCOC(=O)Nc1c(F)cc(Cl)c(F)c1[N+](=O)[O-]>>Nc1c(F)cc(Cl)c(F)c1[N+](=O)[O-],,CC(=O)O,,Br,,test
US07030145B2,Br.COc1ccc(S(=O)(=O)c2ccc(C)nc2Cl)cc1>>Cc1ccc(S(=O)(=O)c2ccc(O)cc2)c(Br)n1,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20030105099A1,CI.COC(=O)[C@H](CCCc1ccccc1)[C@H](O)C(=O)N1CCOCC1>>COC(=O)[C@H](CCCc1ccccc1)C(OC)C(=O)N1CCOCC1,,CN(C)C=O,O,[H-].[Na+],,test
US06448442B1,CC(=O)OCc1c(I)c(N)c(I)c(C(=O)Cl)c1I.OCC(O)CNCC(O)CO>>CC(=O)OCc1c(I)c(N)c(I)c(C(=O)N(CC(O)CO)CC(O)CO)c1I,,C1COCCO1,O,CC#N,CCN(CC)CC,test
US04946858,COC(=O)Cl.NC(=O)c1cc(Cl)c(Cl)cc1C(=O)O>>COC(=O)c1cc(Cl)c(Cl)cc1C#N,,ClCCl,,CCN(CC)CC,,test
US20060122394A1,C1CNCCN1.Cc1cc([N+](=O)[O-])cnc1Cl>>Cc1cc([N+](=O)[O-])cnc1N1CCNCC1,,CC(=O)N(C)C,,,,test
US20150376192A1,FC(F)(F)c1ccccc1Cn1ncc2c(Cl)nc(Cl)nc21.FC1(F)CCNC1>>FC1(F)CCN(c2nc(Cl)nc3c2cnn3Cc2ccccc2C(F)(F)F)C1,,C1COCCO1,,CCN(C(C)C)C(C)C,Cl,test
US05147445,CCN(CC)C(=O)n1cnc(Sc2ccc(C(F)(F)F)cc2Cl)n1.O=C(OO)c1cccc(Cl)c1>>CCN(CC)C(=O)n1cnc(S(=O)c2ccc(C(F)(F)F)cc2Cl)n1,,ClC(Cl)Cl,,,,test
US20010041700A1,CC=O.NCC(NC(=O)C(CC(=O)N1CCOCC1)CC1CCCCC1)C(N)=O.O=C1CCCCC1>>CCN(CC(C#N)NC(=O)C(CC(=O)N1CCOCC1)CC1CCCCC1)C1CCCCC1,,C1CCOC1,,O=C(O)C(F)(F)F,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160052922A1,CC(C)n1ncc2c(N3CCOCC3)nc(Cl)nc21.COc1cc(O)cc(B2OC(C)(C)C(C)(C)O2)c1>>COc1cc(O)cc(-c2nc(N3CCOCC3)c3cnn(C(C)C)c3n2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])O.[Na+],,test
US20110130398A1,O=C1Cc2ccc(Cl)cc2N1.O=Cc1cc(F)cc(Cl)c1>>O=C1Nc2cc(Cl)ccc2/C1=C/c1cc(F)cc(Cl)c1,,CO,,C1CCNCC1,,test
US05491241,CCOC(=O)C1C2C=CC(=O)C2CN1C(=O)OCc1ccccc1.COC(=O)OC(=O)OC>>CCOC(=O)C1C2C(=O)CCC2CN1C(=O)OC,[Pd],C1CCOC1,,[H][H],,test
US20090209529A1,CC(=O)c1cccc(Br)c1.CCOc1ccc(Br)cc1>>C=C(c1ccc(OCC)cc1)c1cccc(Br)c1,,C1CCOC1,,Cl,[Li]CCCC,test
US04159338,N#C[S-].O=C(c1ccco1)C(O)c1ccco1.[NH4+]>>Sc1nc(-c2ccco2)c(-c2ccco2)[nH]1,,CCO,,,,test
US20110281838A1,Cc1nc(N)nc(N2CCC(NC(=O)OC(C)(C)C)CC2)c1C#Cc1ccc(N)nc1>>Cc1nc(N)nc(N2CCC(N)CC2)c1C#Cc1ccc(N)nc1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],test
US20120205645A1,Brc1cccc2c1oc1ccccc12.c1c[nH]cn1>>c1ccc2c(c1)oc1c(-n3ccnc3)cccc12,[Cu]I,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060173050A1,CC(C)I.COC(OC)c1cc(SC)c(C#N)c(O)n1>>COC(OC)c1cc(SC)c(C#N)c(OC(C)C)n1,,CN(C)C=O,,[Na],,test
US20080113967A1,CC(C)(C)c1cc(N)n(-c2ccc3c(c2)C(=S)NCC3)n1.O=C=Nc1cccc(Cl)c1Cl>>CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)n(-c2ccc3c(c2)C(=S)NCC3)n1,,C1CCOC1,,c1ccncc1,,test
US20140249199A1,COC(=O)C(=[N+]=[N-])c1ccc2ccccc2c1.COc1ccco1>>COC(=O)/C=C\C=C(\C(=O)OC)c1ccc2ccccc2c1,,CCCCCC,,,,test
US20090054681A1,C=C[Mg]Cl.O=Cc1cccc(F)c1O>>C=CC(O)c1cccc(F)c1O,,C1CCOC1,,[Cl-].[NH4+],,test
US20060154979A1,CCOC1(Cl)C=CC(O)=C(Cl)C1.COC(=O)C(C)(C)Sc1ccc(O)cc1>>COC(=O)C(C)(C)Sc1ccc(OCCc2ccc(Cl)cc2Cl)cc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100069351A1,Clc1ccc(-n2ccnc2)nn1.c1ccc2c(c1)COC21CCNC1>>c1ccc2c(c1)COC21CCN(c2ccc(-n3ccnc3)nn2)C1,,CCN(CC)CC,,Cl,,test
US20040204448A1,CCOc1cc(C(CC(=O)O)N2Cc3cccc(NC(=O)C4CC4)c3C2=O)ccc1OC(F)F.CNC>>CCOc1cc(C(CC(=O)N(C)C)N2Cc3cccc(NC(=O)C4CC4)c3C2=O)ccc1OC(F)F,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCS(=O)(=O)CC1.Oc1ccc2cccnc2c1>>COc1cc2c(Oc3ccc4cccnc4c3)ncnc2cc1OCCCN1CCS(=O)(=O)CC1,,CN(C)C=O,,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20150284395A1,C#CCN.CCn1ncc2cc(-c3cc(=O)n4nc(C)c(C(=O)O)c4[nH]3)ccc21>>C#CCNC(=O)c1c(C)nn2c(=O)cc(-c3ccc4c(cnn4CC)c3)[nH]c12,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US04241060,Cl.O=[N+]([O-])c1nccn1CC(O)CN1CCCCC1>>Cl.O=[N+]([O-])c1nccn1CC(O)CN1CCCCC1,,CCO,,,,test
US07273856B2,CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)O.NCCCN1CCOCC1>>CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)NCCCN1CCOCC1,,C1CCOC1,,,,test
US20140107151A1,C1CCNCC1.N#CCC(=O)N1CCC(c2cc3[nH]nc(N)c3c(-c3ccc(Oc4ccccc4)cc3)n2)CC1>>N#CC(=CC1CC1)C(=O)N1CCC(c2cc3[nH]nc(N)c3c(-c3ccc(Oc4ccccc4)cc3)n2)CC1,,CO,,N#N,,test
US20080108676A1,Cc1cc(C(F)(F)F)ccc1N.Cc1nc2cc(C(=O)O)ccc2s1>>Cc1nc2cc(C(=O)Nc3ccc(C(F)(F)F)cc3C)ccc2s1,CN(C)c1ccncc1,CN(C)C=O,ClCCl,ClCCCl,,test
US20130281366A1,CCC(=NOCc1ccc(C(F)(F)F)cc1)c1ccc(NC(C)=O)cc1>>CCC(=NOCc1ccc(C(F)(F)F)cc1)c1ccc(N)cc1,,CCO,O,[K+].[OH-],,test
US20130053386A1,CCn1nc(-c2cccc(C(C)(C)NS(=O)(=O)CC(F)(F)F)c2)cc1Oc1ccc(C(=O)O)cc1.NCC1CCCO1>>O=C(NCC1CCCO1)c1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20050277772A1,COc1ccc2ccc(O)c(-c3nnc(Cl)c4ccccc34)c2c1.C[C@@H](O)c1ccccc1>>COc1ccc2ccc(O)c(-c3nnc(O[C@H](C)c4ccccc4)c4ccccc34)c2c1,,C1CCOC1,,[H-].[Na+],,test
US20020028820A1,CCOC(=O)c1cc(O)cc(Oc2nc(Oc3cccc(C#N)c3)c(F)c(C)c2F)c1.CI>>CCOC(=O)c1cc(OC)cc(Oc2nc(Oc3cccc(C#N)c3)c(F)c(C)c2F)c1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04409018,O=C1N(c2ccc(Cl)cc2F)C(=S)C2CCCCC12O>>O=C1C2=C(CCCC2)C(=S)N1c1ccc(Cl)cc1F,,c1ccncc1,,CC(=O)OC(C)=O,,test
US20070161615A1,CCCC(=O)Cl.CCNc1cnoc1C>>CCCC(=O)N(CC)c1cnoc1C,,ClCCl,,CCN(CC)CC,,test
US20060052595A1,C=C[Mg]Br.O=C(CCCl)c1ccccc1>>C=CC(O)(CCCl)c1ccccc1,,C1CCOC1,,,,test
US05334716,CC(C)=O.CCOP(=O)(Cc1ccc(C(=O)OC)c(OC)c1)OCC>>COC(=O)c1ccc(C=C(C)C)cc1OC,,CN(C)C=O,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20080275018A1,CC(C)(C)OC(=O)NCCC[C@@H](CN)NC(=O)OC(C)(C)C.CC(C)(C)OC(=O)N[C@@H](CCCNC(=O)OCc1ccccc1)CCC(=O)O>>CC(C)(C)OC(=O)NCCC[C@@H](CNC(=O)C[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20030166639A1,CC(C)(C)OC(=O)Nc1cc(OCC2CC2)c(C(F)(F)F)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)Nc1cc(OCC2CC2)c(C(F)(F)F)cc1N,[Pd],,,,,test
US20150274696A1,CC(=S)Nc1cc(F)ccc1F>>Cc1nc2cc(F)ccc2s1,,Cc1ccccc1C,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120071482A1,CC1(C)O[C@H]2[C@H](Nc3nc(Cl)nc(N[C@H]4CCc5ccccc54)n3)C[C@H](CO)[C@H]2O1>>CC1(C)O[C@H]2[C@H](Nc3ncnc(N[C@H]4CCc5ccccc54)n3)C[C@H](CO)[C@H]2O1,[Pd],CCO,,,,test
US04244963,O=C(O)CCl.Sc1ccc(Cl)cc1>>OC(=S)Cc1ccc(Cl)cc1,,O,,[Na+].[OH-],,test
US20130172339A1,Nc1cccc(-c2nnn[nH]2)c1.O=S(=O)(Cl)c1ccc(-c2ccon2)s1>>O=S(=O)(Nc1cccc(-c2nnn[nH]2)c1)c1ccc(-c2ccon2)s1,,O,,O=C(O)C(F)(F)F,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Nc1ccc(F)c(F)c1>>COc1ccc2nc(Nc3ccc(F)c(F)c3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US20040248918A1,Cc1ccc(Nc2nccc(-c3cccnc3)n2)cc1[N+](=O)[O-]>>Cc1ccc(Nc2nccc(-c3cccnc3)n2)cc1N,,CCO,CCOC(C)=O,,,test
US20140243286A1,COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCOCCOCCN)c1nnc(C)n1-2.O=C(O)c1cccc(O)c1O>>COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCOCCOCCNC(=O)c1cccc(O)c1O)c1nnc(C)n1-2,CN(C)c1ccncc1,CN(C)C=O,ClCCl,CCN=C=NCCCN(C)C,,test
US20160075692A1,Cc1cncc(CCl)n1.O=C1NCCN1c1cccc2c1cnn2-c1ccccc1F>>Cc1cncc(CN2CCN(c3cccc4c3cnn4-c3ccccc3F)C2=O)n1,,C1CCOC1,,[H-].[Na+],,test
US20160016914A1,CCOC(=O)c1cnc2cc(O)ccn12.Fc1ccccn1>>CCOC(=O)c1cnc2cc(Oc3ccccn3)ccn12,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20140094473A1,CC(C)(C)C(CC(N)=O)Nc1nc(-c2c[nH]c3ncc(F)cc23)ncc1F>>CC(C)(C)C(CC#N)Nc1nc(-c2c[nH]c3ncc(F)cc23)ncc1F,,c1ccncc1,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US05725798,CC(=O)O.O=Cc1ccc(C(=O)OCc2ccccc2)cc1>>O=C(O)c1ccc(C(=O)OCc2ccccc2)cc1,,O,,,,test
US20100041663A1,C[C@@H]1CNCCN1.Cc1c(Cl)nnc(Cl)c1C>>Cc1c(Cl)nnc(N2CCN[C@H](C)C2)c1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140031364A1,Clc1ccc(N2CCNCC2)cc1Cl.Nc1onc(-c2ccccc2F)c1C(=O)O>>Nc1onc(-c2ccccc2F)c1C(=O)N1CCN(c2ccc(Cl)c(Cl)c2)CC1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US08629168B2,CSc1nc2cccc(Br)c2o1.Cc1cc(N)ccc1C(=O)N(C)C>>Cc1cc(Nc2nc3cccc(Br)c3o2)ccc1C(=O)N(C)C,,ClCCl,,O=C(OO)c1cccc(Cl)c1,,test
US06486190B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cc2nc(N)[nH]c2c(C)c1[N+](=O)[O-]>>Cc1cc2nc(NC(=O)OC(C)(C)C)[nH]c2c(C)c1[N+](=O)[O-],,CCOC(C)=O,CO,CCN(CC)CC,CN(C)c1ccccn1,test
US20100197687A1,CN(C)C=O.O=C(O)c1cc2cc(Br)ccc2[nH]1>>NC(=O)c1cc2cc(Br)ccc2[nH]1,,CCOCC,,O=S(Cl)Cl,,test
US20150175567A1,CC(C)OC(=O)COc1cccc(N)c1.O=C1CCCc2ccc(-c3cccc(F)c3)cc21>>CC(C)OC(=O)COc1cccc(N=C2CCCc3ccc(-c4cccc(F)c4)cc32)c1,,Cc1ccccc1,,,,test
US07390830B1,FC(F)(F)Sc1ccc(CCl)cc1.Nc1ccc(Cl)cc1C(=O)NCC(=O)NCC1CCNCC1>>Nc1ccc(Cl)cc1C(=O)NCC(=O)NCC1CCN(Cc2ccc(SC(F)(F)F)cc2)CC1,,ClC(Cl)Cl,,CC#N,,test
US20070004679A1,CC(=O)Cl.N#Cc1ccc(N2CCCC(CN)C2)c2ccccc12>>CC(=O)NCC1CCCN(c2ccc(C#N)c3ccccc23)C1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20030162777A1,C=CC(=O)N1c2ccccc2CCC1CN1CCN(c2cccc3[nH]ccc23)CC1.NCc1ccccc1>>O=C(CCNCc1ccccc1)N1c2ccccc2CCC1CN1CCN(c2cccc3[nH]ccc23)CC1,,O,,,,test
US20160122344A1,CCOC=C(C(C)=O)C(=O)OCC.CCOc1cc2c(cc1OCC)CC(CN1C(=O)c3ccccc3C1=O)N=C2>>CCOC(=O)C1=CN2C(CN3C(=O)c4ccccc4C3=O)Cc3cc(OCC)c(OCC)cc3C2CC1=O,,CCO,,,,test
US20090054555A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCCCCCCCCCCC(=O)O>>CC(C)(C)OC(=O)C(CCCCCCCCCCN)C(=O)O,,C1COCCO1,,O,[Na+].[OH-],test
US20100022580A1,CC(C)O.CN1CCc2c(c3cc(Cl)ccc3n2CC(=O)O)C1>>CC(C)OC(=O)Cn1c2c(c3cc(Cl)ccc31)CN(C)CC2,,CC(C)O,,CCN=C=NCCCN(C)C,,test
US20140343083A1,CC(C(=O)O)c1ccc(O)cc1.CCN>>CCNC(=O)C(C)c1ccc(O)cc1,,C1CCOC1,CN(C)C=O,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,test
US20110152299A1,Cc1csc(N)n1.O=C(O)c1cc(F)cc(Oc2cncnc2)c1>>Cc1csc(NC(=O)c2cc(F)cc(Oc3cncnc3)c2)n1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100249119A1,N#CC1(c2cccc(C(=O)Nc3cc(Oc4ccc5nc(N)sc5n4)c(F)cc3F)c2Cl)CC1.O=C(Cl)C1CC1>>N#CC1(c2cccc(C(=O)Nc3cc(Oc4ccc5nc(NC(=O)C6CC6)sc5n4)c(F)cc3F)c2Cl)CC1,CN(C)c1ccncc1,c1ccncc1,,O,,test
US20100292210A1,COc1cc(Nc2ccc3c(n2)O[C@H](c2ccccc2)CN(C(=O)OC(C)(C)C)C3)ccc1-n1cnc(C)c1>>COc1cc(Nc2ccc3c(n2)O[C@H](c2ccccc2)CNC3)ccc1-n1cnc(C)c1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20080146575A1,C1CNCCN1.O=C(Cl)C1CC1>>Cl.O=C(C1CC1)N1CCNCC1,,CC(=O)O,,,,test
US08513270B2,Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1-c1cccc(N)c1.Clc1ncccc1Br>>Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1-c1cccc(Nc2ncccc2Br)c1,,CO,,,,test
US20140163033A1,Nc1cc(F)cc(F)c1.O=C(O)c1ncc[nH]1>>O=C(Nc1cc(F)cc(F)c1)c1ncc[nH]1,,CN(C)C=O,,On1nnc2ccccc21,,test
US20070032530A1,ClCc1cccc(-c2ccc(Cl)cc2)n1.Oc1ccc(CCCCn2ccnn2)cc1>>Clc1ccc(-c2cccc(COc3ccc(CCCCn4ccnn4)cc3)n2)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US06825219B2,CCOC(=O)CCCn1c(N)nc2cc(C(=O)N(C)C3CCCCC3)ccc21.O=C(Cl)c1cccs1>>CCOC(=O)CCCn1c(NC(=O)c2cccs2)nc2cc(C(=O)N(C)C3CCCCC3)ccc21,,c1ccncc1,,,,test
US05849796,COC(=O)c1cc(S(C)(=O)=O)c(Br)cc1C.N=C(N)N>>Cc1cc(Br)c(S(C)(=O)=O)cc1C(=O)N=C(N)N,,CO,,,,test
US06265421B1,CCOC(=O)C(C(C)=O)C1CCCC1.Oc1cc(O)cc(O)c1>>Cc1c(C2CCCC2)c(=O)oc2cc(O)cc(O)c12,,CCO,,Cl,,test
US20030069230A1,Cc1cccc(-n2cnc3c2CCN(Cc2ccccc2)C3)c1>>Cc1cccc(-n2cnc3c2CCNC3)c1,[Pd],CO,,O=C[O-].[NH4+],,test
US20060247179A1,CC(C)(C)OC(=O)NC(C)(C)C(=O)OCc1ccccc1.Cl>>CC(C)(N)C(=O)OCc1ccccc1.Cl,,CCOCC,,,,test
US20110257151A1,COC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(OC(C)(C)C(=O)OC)c1)=N2>>COC(=O)c1ccc2c(c1)CC(C)(C)C(c1cccc(OC(C)(C)C(=O)OC)c1)N2,[Pd],C1CCOC1,CO,,,test
US20040102325A1,C#CCO.Fc1ccc(Br)cn1>>C#CCOc1ccc(Br)cn1,,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US05576321,FC(F)(F)c1ccccc1N1CCNCC1.O=C(O)C(=O)O.c1cc(OC[C@@H]2CO2)c2cc[nH]c2c1>>O=C(O)C(=O)O.O[C@H](COc1cccc2[nH]ccc12)CN1CCN(c2ccccc2C(F)(F)F)CC1,,CCOC(C)=O,,CO,,test
US20130281392A1,Nc1cc(Cl)c(-c2ccc(C(F)(F)F)cc2Cl)cc1[N+](=O)[O-]>>Nc1cc(Cl)c(-c2ccc(C(F)(F)F)cc2Cl)cc1N,[Zn],CCO,,Cl,,test
US20100286129A1,CC(=O)c1ccc(F)c([N+](=O)[O-])c1.CC(C)CN>>CC(=O)c1ccc(NCC(C)C)c([N+](=O)[O-])c1,,CC#N,,O,O=C([O-])O.[Na+],test
US20090042929A1,CSc1ccc(CN(C)C(=O)C23CC4CC(CC(C4)C2)C3)s1.O=C(OO)c1cccc(Cl)c1>>CN(Cc1ccc(S(C)=O)s1)C(=O)C12CC3CC(CC(C3)C1)C2,,ClCCl,,,,test
US20130345444A1,COC(=O)Cc1coc2cc(O)ccc12.Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(CCl)c1>>Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(COc2ccc3c(CC(=O)O)coc3c2)c1,,CN(C)C=O,O,Cc1ccccc1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20080207902A1,COc1ccc(C2=NNC(=O)CC2C)c2cc(C=O)nn12.C[Mg]Br>>COc1ccc(C2=NNC(=O)CC2C)c2cc(C(C)O)nn12,,C1CCOC1,,,,test
US20050031993A1,CC(=O)CCc1ccc(Br)cc1F.CN(N)c1ccccc1>>c1ccc2[nH]ccc2c1,,Cc1ccccc1,,CCO,Cl,test
US20090253687A1,NNc1ccc(F)cc1.O=C1CSc2ccc(C(=O)CC(=O)C(F)(F)F)cc2N1>>O=C1CSc2ccc(-c3cc(C(F)(F)F)nn3-c3ccc(F)cc3)cc2N1,,CCN(CC)CC,,Cl,,test
US20040082780A1,FC(F)(F)c1ccc(-c2cc(Cl)ncn2)cc1.Oc1ccccc1Br>>FC(F)(F)c1ccc(-c2cc(Oc3ccccc3Br)ncn2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20130131039A1,CN1CCC(c2ccc(-c3cc4nccn4c(-c4cn[nH]c4)n3)cc2)CC1.N#CC=CC1CCCC1>>CN1CCC(c2ccc(-c3cc4nccn4c(-c4cnn(C(CC#N)C5CCCC5)c4)n3)cc2)CC1,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20070148164A1,Cl.N#Cc1cc(Oc2nc(-c3ccccc3C(=O)O)c(F)cc2F)cc(-c2cccc(CN)c2)c1>>Cl.N#Cc1cc(Oc2nc(-c3ccccc3C(=O)O)c(F)cc2F)cc(-c2cccc(CN)c2)c1,,CC#N,O,,,test
US20060025395A1,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.COc1ccc(C2OC[C@H](C)[C@@H]([C@@H](C)[C@H](O)CC[C@H](C)C[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)/C=C\[C@H](C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](C)/C=C/COC(c3ccccc3)(c3ccccc3)c3ccccc3)O[Si](C)(C)C(C)(C)C)O2)cc1>>COc1ccc(C2OC[C@H](C)[C@@H]([C@@H](C)[C@@H](CC[C@H](C)C[C@H](C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)/C=C\[C@H](C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](C)/C=C/COC(c3ccccc3)(c3ccccc3)c3ccccc3)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O2)cc1,,ClCCl,,Cc1cccc(C)n1,,test
US20070124152A1,CS(=O)(=O)Cl.NCCn1c(=O)c(C(=O)NCCCN2CCOCC2)c(O)c2ncc(Cc3ccc(F)cc3)cc21>>CS(=O)(=O)NCCn1c(=O)c(C(=O)NCCCN2CCOCC2)c(O)c2ncc(Cc3ccc(F)cc3)cc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20130216498A1,CC(C)(C)OC(=O)N1CCC[C@@H](Nc2nc(-c3cnc4ccc(F)cn34)ncc2[N+](=O)[O-])C1>>O=[N+]([O-])c1cnc(-c2cnc3ccc(F)cn23)nc1N[C@@H]1CCCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100137299A1,COc1ccc(CN2C(=O)C3(COc4cc(O)c(C#N)cc43)c3ccccc32)cc1.NO>>COc1ccc(CN2C(=O)C3(COc4cc(O)c(C(N)=NO)cc43)c3ccccc32)cc1,,CCO,,CCN(CC)CC,Cl,test
US20130336921A1,C1CCNCC1.O=C(Nc1ncn(-c2cccc(C(F)(F)F)c2)n1)c1cc(Cl)ccc1[N+](=O)[O-]>>O=C(Nc1ncn(-c2cccc(C(F)(F)F)c2)n1)c1cc(N2CCCCC2)ccc1[N+](=O)[O-],,CN(C)C=O,,,,test
US20070219210A1,CCOC(=O)c1cc(-c2ccc(C#N)cc2)n(-c2cccnc2)n1>>N#Cc1ccc(-c2cc(C(=O)O)nn2-c2cccnc2)cc1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US04806553,CSC(=S)C[N+](=O)[O-].NCCNCc1ccc(Cl)nc1>>O=[N+]([O-])C=C(S)NCCNCc1ccc(Cl)nc1,,CO,,,,test
US05332831,CCc1nc(C2CC2)c(C(N)=O)n1Cc1ccc2oc(-c3ccccc3NS(=O)(=O)C(F)(F)F)c(Br)c2c1.N>>CCc1nc(C2CC2)c(C([NH-])=O)n1Cc1ccc2oc(-c3ccccc3NS(=O)(=O)C(F)(F)F)c(Br)c2c1.[NH4+],,CCO,,,,test
US06043358,CC(C)(C)OC(=O)N1CCNC(=N)CC1.Cl.Cl>>Cl.Cl.N=C1CCNCCN1,,CCOC(C)=O,,,,test
US20120101100A1,CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2cncc(-c3n[nH]c(=O)o3)c2)cn1.OC1CNC1>>CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2cncc(C(=O)NNC(=O)N3CC(O)C3)c2)cn1,,CCO,,,,test
US20140206673A1,Cc1ccc(S(=O)(=O)N2CC(F)CN(S(=O)(=O)c3ccc(C)cc3)C(C)C2)cc1>>CC1CNCC(F)CN1,,Br,CC(=O)O,,,test
US20070093521A1,CCOc1cc(C=O)cc(OCC)c1F.Cc1nccc2nc(NC3CCNCC3)oc12>>CCOc1cc(CN2CCC(Nc3nc4ccnc(C)c4o3)CC2)cc(OCC)c1F,,CC(=O)O,CCO,CCN(C(C)C)C(C)C,[BH3-]C#N.[Na+],test
US20050131239A1,CSc1ccc(B(O)O)cc1.O=C1OCC(Cl)=C1Cl>>CSc1ccc(C2=C(Cl)C(=O)OC2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,[Cs+].[F-],,test
US20080171872A1,CC#N.CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(=O)O>>c1ccc(CCNCc2ccccc2)cc1,,CC#N,,,,test
US20100210622A1,CC(C)(C)OC(=O)c1nc(N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)ccc1CCC=O>>CC(C)(C)OC(=O)c1nc(N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)ccc1CCCO,,C1CCOC1,CO,[BH4-].[Na+],,test
US04476125,CCOC(=O)C(=O)N(c1ccccc1)c1cc(OC)c([N+](=O)[O-])cc1OC>>CCOC(=O)C(=O)N(c1ccccc1)c1cc(OC)c(N)cc1OC,,CCO,,,,test
US20150166574A1,CCOC(=O)c1cn2cc(-c3ccccc3)sc2n1>>OCc1cn2cc(-c3ccccc3)sc2n1,,ClCCl,O,CC(C)C[AlH]CC(C)C,,test
US20070010511A1,COCCCCl.COc1ccccc1COCCCOc1ccc([C@H]2CCN(C(=O)OC(C)(C)C)C[C@@H]2OCc2ccc3oc(=O)[nH]c3c2)cc1>>COCCCn1c(=O)oc2ccc(COC3CN(C(=O)OC(C)(C)C)CCC3c3ccc(OCCCOCc4ccccc4OC)cc3)cc21,,CN(C)C=O,,[H-].[Na+],,test
US04471138,CC(O)OCCCl.CCC(C)(N)CC>>CCC(C)(CC)NCCOC(C)O,,COCCO,,[K+].[OH-],,test
US05959107,CC(=O)C(C)=O.Nc1ccc(S(=O)(=O)c2cccc3cnccc23)cc1N>>Cc1nc2ccc(S(=O)(=O)c3cccc4cnccc34)cc2nc1C,,CCO,,,,test
US20100249139A1,CC(c1ccc(N)cc1Cl)C(O)(c1ccnc(Cl)c1)C(F)(F)F.COC(=O)c1cccc(C(=O)[O-])c1>>COC(=O)c1cccc(C(=O)Nc2ccc(C(C)C(O)(c3ccnc(Cl)c3)C(F)(F)F)c(Cl)c2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080319078A1,CCCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(OCC(=O)OCC)cc1>>CCCC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(OCC(=O)O)cc1,,CCO,,C1CCOC1,[Na+].[OH-],test
US20050288293A1,CC(C)(C)OC(=O)N1CCN(Cc2ccc(Cl)cc2)C(=O)C1>>O=C1CNCCN1Cc1ccc(Cl)cc1,,CCOC(C)=O,,Cl,,test
US20140073620A1,C=O.NC(=O)C1(c2ccccc2CCc2nc(Nc3ccc(C4CCNCC4)cc3)ncc2Cl)CC1>>CN1CCC(c2ccc(Nc3ncc(Cl)c(CCc4ccccc4C4(C(N)=O)CC4)n3)cc2)CC1,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05723499,CC(C)(C)[Si](C)(C)Cl.Oc1cc2ccc(Br)cc2cc1C12CC3CC(CC(C3)C1)C2>>CC(C)(C)[Si](C)(C)Oc1cc2ccc(Br)cc2cc1C12CC3CC(CC(C3)C1)C2,CN(C)c1ccncc1,O,,CCN(CC)CC,CN(C)C=O,test
US20100144760A1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H]2C[C@H]1CN.FC(F)(F)c1ccc(Cl)nn1>>CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H]2C[C@H]1CNc1ccc(C(F)(F)F)nn1,,CS(C)=O,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20140243286A1,BrCCBr.Oc1ccc(Br)cc1>>BrCCOc1cccc(Br)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120302573A1,CC(=O)C(OS(=O)(=O)c1ccc(C)cc1)C(=O)C(F)(F)F.NC(N)=S>>CC(=O)c1sc(N)nc1C(F)(F)F,,CC#N,,,,test
US20120149662A1,CC(C)(C)C(=O)OCn1ccc2c(-c3cnn([C@@H](CC#N)C4CCCC4)c3)cnnc21>>N#CC[C@@H](C1CCCC1)n1cc(-c2cnnc3[nH]ccc23)cn1,,CO,,[Na+].[OH-],,test
US20140275030A1,Cc1noc(C)c1B(O)O.O=c1[nH]c2ccc(Br)c3c2n1C(C1CCCCN1)CO3>>Cc1noc(C)c1-c1ccc2[nH]c(=O)n3c2c1OCC3C1CCCCN1,,C1COCCO1,O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US08828987B2,COC(=O)c1cc(Cl)cnc1N1CC(OS(C)(=O)=O)C1.Oc1cccc(F)c1>>COC(=O)c1cc(Cl)cnc1N1CC(Oc2cccc(F)c2)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100292190A1,C#Cc1ccco1.COc1cc(C=O)cc(OC)c1OC>>COc1cc(C(=O)C#Cc2ccco2)cc(OC)c1OC,,C1CCOC1,,[Li]CCCC,,test
US20050101647A1,CC(=O)OC(C)=O.Nc1ccc(CCc2nc3ncc(-c4ccccc4)cc3[nH]2)cc1>>CC(=O)Nc1ccc(CCc2nc3ncc(-c4ccccc4)cc3[nH]2)cc1,,c1ccncc1,,C,O=C[O-].[NH4+],test
US05932595,Brc1ccc(Oc2ccccc2)cc1.C[S-]>>Sc1ccc(Oc2ccccc2)cc1,,CN(C)C=O,,[Na+].[OH-],,test
US20160090381A1,Cl.Cn1cc(C2=CCN(C(=O)OC(C)(C)C)CC2)c2c(C(F)(F)F)c([N+](=O)[O-])cnc21>>Cl.Cn1cc(C2=CCNCC2)c2c(C(F)(F)F)c([N+](=O)[O-])cnc21,,CCOC(C)=O,ClCCl,C1COCCO1,,test
US20010006969A1,C=CCNc1nc(Cl)nc2ccc([N+](=O)[O-])cc12.CC(C)(C)CN>>C=CCNc1nc(NCC(C)(C)C)nc2ccc([N+](=O)[O-])cc12,,CC#N,,O,,test
US20050239832A1,OC1=CCOc2ccc(I)cc21>>O=C1CCOc2ccc(I)cc21,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20090062125A1,CCOC(C)=O.COc1c(Cl)ccc(-c2nc(N)c(Br)c(C(=O)O)n2)c1F.C[S-]>>COC(=O)c1nc(-c2ccc(Cl)c(OC)c2F)nc(N)c1SC,,CN(C)C=O,O,Cl,,test
US05563162,COc1cccc2c(Cl)nc(C)nc12>>COc1cccc2cnc(C)nc12,[Pd],CCOC(C)=O,,CCN(CC)CC,,test
US20100168105A1,CCOC(=O)C1CC12CCNCC2.O=C1CCOCC1>>CCOC(=O)C1CC12CCN(C1CCOCC1)CC2,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20120259123A1,CC(C)(CCOC(F)F)c1ccc(CBr)cc1.CCOC(=O)CNc1cccc(CNS(=O)(=O)c2ccccn2)n1>>CCOC(=O)CNc1cccc(C(Cc2ccc(C(C)(C)CCOC(F)F)cc2)NS(=O)(=O)c2ccccn2)n1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20090105214A1,COC[C@H](C)Oc1cc(O)cc(C(=O)Nc2cnc(C)cn2)c1.O=S1(=O)CCCOc2cc(F)ccc21>>COC[C@H](C)Oc1cc(Oc2ccc3c(c2)OCCCS3(=O)=O)cc(C(=O)Nc2cnc(C)cn2)c1,,CC#N,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20070149508A1,CC(C)(C)OC(=O)N1CCC(CBr)CC1.Sc1ccc(Br)cc1>>CC(C)(C)OC(=O)N1CCC(CSc2ccc(Br)cc2)CC1,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110105460A1,CCOC(=O)C(=O)Cl.Cn1c(-c2ccccc2C(F)(F)F)nnc1C(C)(C)Oc1ccc(Cl)cc1C(=O)NN>>CCOC(=O)c1nnc(-c2cc(Cl)ccc2OC(C)(C)c2nnc(-c3ccccc3C(F)(F)F)n2C)o1,,C1CCOC1,,CCN(CC)CC,O,test
US20060173018A1,Cc1ccc2c(N3CC[C@@H](NC(=O)O[C@H]4CCOC4)C3)nc(-c3ccccc3O)nc2c1.Cl>>Cc1ccc2c(N3CC[C@@H](NC(=O)O[C@H]4CCOC4)C3)nc(-c3ccccc3O)nc2c1.Cl,,ClCCl,,CCOCC,,test
US20110312935A1,Cc1ccnc(NC(=O)c2ccc(N)c([N+](=O)[O-])c2)c1>>Cc1ccnc(NC(=O)c2ccc(N)c(N)c2)c1,[Ni],C1CCOC1,,,,test
US20060160853A1,O=C(c1ccccc1)C1CCN(Cc2nc3cc(O)ccc3[nH]2)CC1>>Oc1ccc2[nH]c(CN3CCC(C(O)c4ccccc4)CC3)nc2c1,,CO,,[BH4-].[Na+],,test
US20140094459A1,CC(C)(C)OC(=O)N1CCC[C@@H](n2nc(I)c3c(N)ncnc32)C1.CC1(C)OB(c2ccc(Oc3cc(F)cc(F)c3)cc2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4cc(F)cc(F)c4)cc3)c3c(N)ncnc32)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20160137639A1,CC(C)(C)OC(=O)C[C@H](CCCOCc1ccccc1)c1noc(-c2cc(C(F)(F)C(C)(C)C)on2)c1C(F)F>>CC(C)(C)C(F)(F)c1cc(-c2onc([C@@H](CCCOCc3ccccc3)CC(=O)O)c2C(F)F)no1,,Cc1ccccc1,,O=C(O)C(F)(F)F,,test
US20040144708A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)O.Cc1cc(C)cc(N)c1>>Cc1cc(C)cc(NC(=O)[C@@H](C)N)c1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20150126364A1,CI.Fc1ccc(-c2[nH]c(-c3cccc(C(F)(F)F)c3)nc2CN2CCOCC2)c(F)c1>>Cn1c(-c2cccc(C(F)(F)F)c2)nc(-c2ccc(F)cc2F)c1CN1CCOCC1,,C1CCOC1,,[H-].[Na+],,test
US20130281433A1,BrBr.Clc1ccc2[nH]ncc2c1>>Clc1ccc2[nH]nc(Br)c2c1,,CN(C)C=O,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20100004300A1,O=C1[C@@H](N2CCC(c3cc(Cl)cc(Cl)c3)C2)CCN1c1cc(F)cc(F)c1.O=S(=O)(O)Cl>>O=C1[C@@H](N2CCC(c3cc(Cl)cc(Cl)c3)C2)CCN1c1cc(F)c(S(=O)(=O)Cl)c(F)c1,,ClCCCl,,O,,test
US20160152616A1,COC1O[C@H](Cn2c(=O)n3c4c(cccc42)C(C)(C)CC3)[C@H]2OC(C)(C)O[C@@H]12>>COC1O[C@H](Cn2c(=O)n3c4c(cccc42)C(C)(C)CC3)[C@@H](O)[C@H]1O,,CC(=O)O,O,,,test
US20140018361A1,CN(C)C1CCC(Nc2nc(Cl)nc3[nH]ccc23)CC1.Nc1ccccc1>>CN(C)C1CCC(Nc2nc(Nc3ccccc3)nc3[nH]ccc23)CC1,,CCCCO,,,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2cc(OC)c(OC)cc23)cc1.Nc1ccc2cn[nH]c2c1>>COc1cc2nc(Nc3ccc4cn[nH]c4c3)c3n[nH]cc3c2cc1OC,C1COCCO1,CO,,Cl,,test
US06166064,CC(C)(C)NS(=O)(=O)c1cccc(S(=O)(=O)Cl)c1.CNC>>CN(C)S(=O)(=O)c1cccc(S(=O)(=O)NC(C)(C)C)c1,,CCOC(C)=O,,O,,test
US04241079,CCCSC1(C)C=CC(=N)C(NC(=S)NC(=O)OC)=C1Cc1ccccc1.CI>>CCCSC1(C)C=CC(=N)C(NC(=NC(=O)OC)SC)=C1Cc1ccccc1,,CC(C)=O,O,[Na+].[OH-],,test
US20090239882A1,CC(=O)NCCCl.Nc1nc2[nH]c(SCc3ccccc3F)nc(=O)c2s1>>CC(=O)NCCOc1nc(SCc2ccccc2F)nc2nc(N)sc12,,CN(C)C=O,,[I-].[Na+],,test
US06110937,CC(=O)Oc1c(C)cc(O)cc1C.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>CC(=O)Oc1c(C)cc(OCC(F)(F)F)cc1C,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05141945,CCC1(Cc2ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c2C)CCc2c(C)c3ccccc3n2C1=O>>CCC1(Cc2nc[nH]c2C)CCc2c(C)c3ccccc3n2C1=O,,CC(=O)O,O,,,test
US20030087926A1,C=Cc1ccccc1F.CCC(=O)C(=O)[O-].Nc1cc(Cl)cc(Cl)c1>>CCOC(=O)C1CC(c2ccccc2F)c2c(Cl)cc(Cl)cc2N1,,CC#N,,O=C(O)C(F)(F)F,,test
US20120264735A1,CCOC(=O)Cl.Nc1cccc(C(=O)c2nn(-c3ccc(Cl)cc3)ccc2=O)c1>>CCOC(=O)Nc1cccc(C(=O)c2nn(-c3ccc(Cl)cc3)ccc2=O)c1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20150038498A1,CC(C)(C)OC(=O)NCc1ccc(Cl)cc1CNC(=O)[C@@H]1COCCN1C(=O)[C@H](O)C(C)(C)C.O=C(O)C(F)(F)F>>CC(C)(C)[C@@H](O)C(=O)N1CCOC[C@H]1C(=O)NCc1cc(Cl)ccc1CN.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20100069381A1,O=C(OO)c1cccc(Cl)c1.c1ccc(CCc2cc3cccnc3[nH]2)cc1>>[O-][n+]1cccc2cc(CCc3ccccc3)[nH]c21,,CC#N,,,,test
US20100216746A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)c1nc2cc([N+](=O)[O-])ccc2[nH]1>>CC(C)(C)OC(=O)c1nc2cc([N+](=O)[O-])ccc2[nH]1,,ClCCl,,,,test
US20090054435A1,COC(=O)[C@@H](C)O.COc1ccc(C(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c(O)c1>>COc1ccc(C(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c(O[C@@H](C)C(=O)O)c1,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05929074,COc1ccc(CNC(=O)OCc2ccccc2)cc1OCC1CO1.Fc1ccc(CN2CCNCC2)cc1>>COc1ccc(CNC(=O)OCc2ccccc2)cc1OCC(O)CN1CCN(Cc2ccc(F)cc2)CC1,,CCO,,,,test
US05880162,CCOc1ccc(C(C)(C)C=C(F)COC(C)=O)cc1.Fc1ccc(Br)cc1Oc1ccccc1>>CCOc1ccc(C(C)(C)C=C(F)Cc2ccc(F)c(Oc3ccccc3)c2)cc1,,C1CCOC1,,[Mg],,test
US20100190787A1,CN1CCNCC1.O=[N+]([O-])c1ccc(CCl)cc1>>NCc1ccc([N+](=O)[O-])cc1,,C1CCOC1,CCOC(C)=O,,,test
US20010037032A1,C(=NC1CCCCC1)=NC1CCCCC1.N#CCCOP(=O)([O-])[O-].c1cc[nH+]cc1.c1cc[nH+]cc1.c1ccncc1>>CCCCCC=CCC=CCC=CC/C=C\CCCC(=O)NCCOP(=O)=O,,c1ccncc1,,O,,test
US20140142126A1,Nc1ncnc2c1c(-c1ccc(Cl)cc1)cn2-c1ccc([N+](=O)[O-])cc1.O=C1CCC(=O)N1Cl>>Nc1ncnc2c1c(-c1ccc(Cl)cc1)c(Cl)n2-c1ccc([N+](=O)[O-])cc1,,ClCCCl,,,,test
US20050014210A1,CCN(C(=O)C(F)(F)F)C(C)Cc1ccc2c(c1)OC(CNC(=O)OCc1ccccc1)O2>>CCN(C(=O)C(F)(F)F)C(C)Cc1ccc2c(c1)OC(CN)O2,[Pd],CO,,,,test
US04789740,C=C(C)C(C(=O)OCc1ccccc1)N1C(=O)C(NC(=O)COc2ccccc2)C1SS(=O)(=O)c1ccccc1.CC(C)(C)OCl>>C=C(CCl)C(C(=O)OCc1ccccc1)N1C(=O)C(NC(=O)COc2ccccc2)C1SS(=O)(=O)c1ccccc1,,c1ccccc1,,O,,test
US05212187,CN(CCCCCCCN)CCC(c1ccccc1)c1ccccn1.N=C(N)Nc1nc(CSCCN)cs1.O=C(n1ccnc1)n1ccnc1>>CN(CCCCCCCNC(=O)NCCSCc1csc(NC(=N)N)n1)CCC(c1ccccc1)c1ccccn1,,ClCCl,,,,test
US04076849,CCCCCC(=O)Cl.c1ccc(NOc2ccccc2)cc1>>CCCCCC(=O)Nc1ccc(Oc2ccccc2)cc1,,[Na+],[OH-],ClCCl,O,test
US20090197866A1,CC(C)(C)OC(=O)N1CCN(c2cc3[nH]c(-c4nn(C5CCCCO5)cc4[N+](=O)[O-])nc3cc2F)CC1>>CC(C)(C)OC(=O)N1CCN(c2cc3[nH]c(-c4nn(C5CCCCO5)cc4N)nc3cc2F)CC1,[Pd],CO,,[H][H],,test
US20140228386A1,O=C1NCCN1c1ccnc(Cl)c1.OC1(c2ccncc2Br)CCCC1>>O=C1N(c2ccnc(Cl)c2)CCN1c1cnccc1C1(O)CCCC1,I[Cu]I,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20040009995A1,CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(Br)c1.Cc1ccc(C(=O)OC(C)(C)C)c(B2OC(C)(C)C(C)(C)O2)c1>>CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2C(=O)OC(C)(C)C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20140051679A1,CC1(C)OB(c2ccc(OC3CN(C4COC4)C3)cc2)OC1(C)C.O=C(NC(c1ccccn1)C1CC1)c1ccc2[nH]nc(I)c2c1>>O=C(NC(c1ccccn1)C1CC1)c1ccc2[nH]nc(-c3ccc(OC4CN(C5COC5)C4)cc3)c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20120184546A1,O=C(Cc1ccc([N+](=O)[O-])cc1)Nc1ccccc1C(=O)O>>O=c1oc(Cc2ccc([N+](=O)[O-])cc2)nc2ccccc12,,CC(=O)OC(C)=O,,,,test
US20150011779A1,CCOC(=O)c1c(C(F)F)nn(-c2ccccc2)c1C(F)(F)F>>O=C(O)c1c(C(F)F)nn(-c2ccccc2)c1C(F)(F)F,,CCO,,[Na+].[OH-],,test
US20070179138A1,CCI.N#Cc1nc(Cl)cc(N)c1[N+](=O)[O-]>>CCNc1cc(Cl)nc(C#N)c1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070055067A1,CC1(C)O[C@H](c2ccc(S(C)(=O)=O)cc2)[C@@H](CF)N1C(=O)C(Cl)Cl>>CS(=O)(=O)c1ccc([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)cc1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20050004095A1,Nc1nnc(SC2=C(C(=O)OC(c3ccccc3)c3ccccc3)N3C(=O)[C@H](NC(=O)/C(=N\OC(c4ccccc4)(c4ccccc4)c4ccccc4)c4nc(N)sc4Cl)C3CC2)s1>>Nc1nnc(SC2=C(C(=O)O)N3C(=O)[C@H](NC(=O)/C(=N\O)c4nc(N)sc4Cl)C3CC2)s1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20100130470A1,O=C1COCc2cc(Br)cnc2N1>>Brc1cnc2c(c1)COCCN2,,C1CCOC1,,,,test
US04843087,BrCCCCCCBr.CCOC(=O)c1ccc(O)cc1>>CCOC(=O)c1ccc(OCCCCCCBr)cc1,,CS(C)=O,,O,[K+].[OH-],test
US20070072847A1,C1COCCN1.N#CC1(O)CCN(Cc2ccccc2)CC1>>N#CC1(N2CCOCC2)CCN(Cc2ccccc2)CC1,,CO,,,,test
US20100310512A1,COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(-c3ccc(C(=O)CN)cc3)cc2)[nH]1)C(C)C.COC(=O)NC1CCCN(C(C)C(=O)O)C1=O>>COC(=O)NC1CCCN(C(C)C(=O)NCC(=O)c2ccc(-c3ccc(-c4cnc(C5CCCN5C(=O)C(NC(=O)OC)C(C)C)[nH]4)cc3)cc2)C1=O,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06759428B2,CI.Cn1c(C(=O)N[C@H]2CCCC[C@H]2C(=O)N[C@H](C#N)Cc2ccc(O)cc2)cc2ccccc21>>COc1ccc(C[C@@H](C#N)NC(=O)[C@@H]2CCCC[C@@H]2NC(=O)c2cc3ccccc3n2C)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20130253012A1,CCOC(OCC)OCC.Cc1c(C(=O)NN)cnn1CC(F)(F)F.Nc1cccnc1>>Cc1c(-c2nncn2-c2cccnc2)cnn1CC(F)(F)F,,CC#N,,CC(=O)O,,test
US20150218165A1,CN(C(=O)OC(C)(C)C)c1cc(F)c(F)cc1Br>>CNc1cc(F)c(F)cc1Br,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130345120A1,C=CCOC(=O)N1CCC(C(=O)O)N1.O=CN(C[C@@H](CC1CCCC1)C(=O)F)OC1CCCCO1>>C=CCOC(=O)N1CCC(C(=O)O)N1C(=O)[C@H](CC1CCCC1)CN(C=O)OC1CCCCO1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20060128635A1,CCOC(=O)c1cn(C(C)C)nc1O.O=C1CCC(=O)N1Br>>CCOC(=O)c1c(O)nn(C(C)C)c1Br,,ClCCl,,,,test
US20130261111A1,CC(C)(O)c1nc(Cl)ncc1F.CCN(CC)S(F)(F)F>>CC(C)(F)c1nc(Cl)ncc1F,,ClCCl,,,,test
US20050107435A1,Cc1cn(C[C@H]2CN(c3ccc(-c4ccc(C5=NOC(CO[Si](C)(C)C(C)(C)C)C5)cc4)c(F)c3)C(=O)O2)nn1>>Cc1cn(C[C@H]2CN(c3ccc(-c4ccc(C5=NOC(CO)C5)cc4)c(F)c3)C(=O)O2)nn1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20160060257A1,CCNS(=O)(=O)Cl.COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCNCC3)cc12>>CCNS(=O)(=O)N1CCC(c2cc3c(-c4cc(F)ccc4OC)ccnc3[nH]2)CC1,,ClCCl,,CCN(CC)CC,,test
US20160083370A1,COc1ccc2[nH]cc(CCCOS(=O)(=O)c3ccc(C)cc3)c2c1.Cc1cc(C)nc(N2CCNCC2)n1>>COc1ccc2[nH]cc(CCCN3CCN(c4nc(C)cc(C)n4)CC3)c2c1,,CC#N,,[I-].[K+],,test
US20160264567A1,COc1nn(-c2cnc(C(F)(F)F)nc2)cc1CO.O=S(Cl)Cl>>COc1nn(-c2cnc(C(F)(F)F)nc2)cc1CCl,,ClCCl,,,,test
US20080234237A1,CC(C)N(CCN1CCCc2cc(NC(=N)c3cccs3)ccc21)C(=O)OC(C)(C)C>>CC(C)NCCN1CCCc2cc(NC(=N)c3cccs3)ccc21,,CO,,Cl,,test
US20110257198A1,CC(C)(C)[Si](C)(C)Cl.Cc1ccc(O)c(CO)n1>>Cc1ccc(O)c(CO[Si](C)(C)C(C)(C)C)n1,,CN(C)C=O,ClCCl,c1c[nH]cn1,,test
US20070004736A1,CC(=O)O.CC(C)(C)OC(=O)CCSc1c(C=O)c2cc(Cl)ccc2n1C(=O)OC(C)(C)C.CN>>CC(=O)N(C)Cc1c(SCCC(=O)OC(C)(C)C)n(C(=O)OC(C)(C)C)c2ccc(Cl)cc12,,CO,ClC(Cl)Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130184455A1,CC(C)(C)OC(=O)NCCO.O=C(O)CBr>>CC(C)(C)OC(=O)NCCOCC(=O)O,,C1CCOC1,,[H-].[Na+],,test
US09375000B2,C[C@H](NC(=O)C1CC1)c1ccc(N2CCC(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1.O=Ic1ccccc1>>C[C@H](NC(=O)C1CC1)c1ccc(N2CCC(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)(C(F)(F)F)C2O)cc1,,ClCCl,,,,test
US05122523,C=C(CC(C)C)C(=O)OCC.CCOC(C)=O.CS>>CCOC(=O)C(CSCC)CC(C)C,,CCOC(C)=O,,CC(C)(C)[O-].[K+],,test
US20160207950A1,CC(C#N)(CO)NC(=O)[c-]1cccc1.N#Cc1ccc(C(F)(F)F)c(F)c1.[Fe+2].c1cc[cH-]c1>>CC(C#N)(COc1cc(C#N)ccc1C(F)(F)F)NC(=O)[c-]1cccc1.[Fe+2].c1cc[cH-]c1,,C1CCOC1,,[H-].[Na+],,test
US20050256316A1,COc1c(Cl)cc(C)c2cnn(S(=O)(=O)c3ccccc3)c12.O=C1CCC(=O)N1Br>>COc1c(Cl)cc(CBr)c2cnn(S(=O)(=O)c3ccccc3)c12,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20160185778A1,CC(C)(C)OC(=O)N1CCc2[nH]nc(CF)c2C1>>FCc1n[nH]c2c1CNCC2,,C1COCCO1,,Cl,,test
US20160272631A1,O=C(NCc1ccccn1)C(=O)c1c(Cl)cccc1Cl>>O=C(c1c(Cl)cccc1Cl)c1ncc2ccccn12,,O=P(Cl)(Cl)Cl,,,,test
US20060211720A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nccc2cc([N+](=O)[O-])ccc12>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nccc2cc(N)ccc12,[Pd],C1CCOC1,CO,[H][H],,test
US05208243,CN.O=C(O)C1CC(=O)N(Cc2ccccc2)C1>>CNC(=O)C1CC(=O)N(Cc2ccccc2)C1,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20150105373A1,COC(=O)C(Br)c1ccc(C(F)(F)F)cc1.[N-]=[N+]=[N-]>>COC(=O)C(N=[N+]=[N-])c1ccc(C(F)(F)F)cc1,,CC#N,,O,,test
US20030060472A1,O=C(CCl)c1cc(O)c(O)c([N+](=O)[O-])c1.Oc1cccc2ccccc12>>O=C(COc1cccc2ccccc12)c1cc(O)c(O)c([N+](=O)[O-])c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04515727,CC(C)(C)[Si](C)(C)Cl.OC/C=C\CCCCl>>CC(C)(C)[Si](C)(C)OC/C=C\CCCCl,,CN(C)C=O,,c1c[nH]cn1,,test
US20150197509A1,COCCNCC(=O)OC.O=S(=O)(Cl)c1ccc(F)cc1>>COCCN(CC(=O)OC)S(=O)(=O)c1ccc(F)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20130237515A1,Cc1cc(CBr)ccc1C(=O)Cn1ccc(OCc2ccc(Br)cn2)cc1=O.OC[C@H]1CCCCN1>>Cc1cc(CN2CCCC[C@@H]2CO)ccc1C(=O)Cn1ccc(OCc2ccc(Br)cn2)cc1=O,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20120283256A1,Clc1ccc2c(Cl)ccnc2c1.N#Cc1cc(N)cc(N)c1>>Cl.N#Cc1cc(N)cc(Nc2ccnc3cc(Cl)ccc23)c1,,CCO,,,,test
US20160068531A1,CCOC(=O)CCn1c(CO)cc2cc(Cl)ccc21.CS(=O)(=O)Cl>>CCOC(=O)CCn1c(COS(C)(=O)=O)cc2cc(Cl)ccc21,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20130261123A1,COC(=O)c1ccc(-c2cnc3cc(OC)ccc3n2)cc1>>COc1ccc2nc(-c3ccc(C(=O)O)cc3)cnc2c1,,CO,,[Na+].[OH-],,test
US20090318476A1,CC(C)(C)ON=O.Nc1cnc(N2CCC(Oc3cc(F)ccc3Br)CC2)nc1N>>Fc1ccc(Br)c(OC2CCN(c3ncc4nn[nH]c4n3)CC2)c1,,C1COCCO1,,,,test
US06441017B1,CC(C)(C)OC(=O)N1CC[C@H](NC(=O)Cc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)C1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)OC(=O)N1CC[C@H](NC(=S)Cc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)C1,,Cc1ccccc1,,,,test
US20120088748A1,CC(C)(C)[Si](C)(C)OCC(CNCc1ccccc1)C(O)c1ccc(Cl)c(Cl)c1.O=C(Cl)CCl>>CC(C)(C)[Si](C)(C)OCC(CN(Cc1ccccc1)C(=O)CCl)C(O)c1ccc(Cl)c(Cl)c1,,C1CCOC1,,CCN(CC)CC,,test
US20030225064A1,NNc1ccc(S(=O)(=O)CF)cc1.O=C(CC(=O)C(F)(F)F)c1ccc(-c2ccco2)cc1>>O=S(=O)(CF)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(-c3ccco3)cc2)cc1,,CCO,,Cl,,test
US20030153604A1,CC(C)(CN)c1ccc(C(=O)NCCc2ccc3[nH]cc(C#N)c3c2)cc1.CS(=O)(=O)Cl>>CC(C)(CNS(C)(=O)=O)c1ccc(C(=O)NCCc2ccc3[nH]cc(C#N)c3c2)cc1,,ClCCl,,c1ccncc1,,test
US20130336920A1,CC(C)(C)OC(=O)N1CCC[C@H](C(=O)O)C1.CNCCOCCOCCOCCOCCOCCOCCOC>>COCCOCCOCCOCCOCCOCCOCCN(C)C(=O)[C@H]1CCCN(C(=O)OC(C)(C)C)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070049616A1,N#Cc1ccc(C2(C(=O)O)CCc3cncn32)c(Cl)c1>>N#Cc1ccc(C2CCc3cncn32)c(Cl)c1,,CS(C)=O,,CCN(CC)CC,,test
US20090102361A1,Brc1cccc(-c2nnc(-c3cccc(-c4ccccn4)n3)n2-c2ccccc2)n1.OB(O)c1cccc2ccccc12>>c1ccc(-n2c(-c3cccc(-c4ccccn4)n3)nnc2-c2cccc(-c3cccc4ccccc34)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[K+].[K+],test
US20150329523A1,COCCOCCOCCOc1cc(N)cc(OC)c1.Cc1ccc(-n2nc(C(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3cccnc23)cc1>>COCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)C)nn4-c4ccc(C)cc4)c4ncccc34)n2)cc(OC)c1,,CN(C)C=O,,C1CCOC1,,test
US05278134,COC(=O)C(=O)N(C)c1ccccc1.Cc1ccc(C2=NC(=O)C(C)(C(C)C)N2)nc1>>Cc1cnc(C2=NC(C)(C(C)C)C(=O)N2)c(C(=O)C(=O)N(C)c2ccccc2)c1,,C1CCOC1,,O,[Li]CCCC,test
US05292452,N#C[C@@H]1CC[C@@H](C=Cc2ccc(-c3ccc(F)c(F)c3)nc2)CC1>>N#C[C@@H]1CC[C@@H](CCc2ccc(-c3ccc(F)c(F)c3)nc2)CC1,[Pd],Cc1ccccc1,,,,test
US20140256771A1,Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1>>Cn1nc(C(F)(F)F)cc1-c1ccc(NCc2c(F)cccc2F)cc1,,C1CCOC1,,CCOC(C)=O,Cl,test
US20160022640A1,CCOC(=O)CC(C)=O.NNCC1CCCCC1>>CC1=NN(CC2CCCCC2)C(=O)C1,,CCO,,Cl,Cl,test
US05017724,CI.Cc1cc(C)c(O)c(C(=O)C2CCCCC2)c1>>COc1c(C)cc(C)cc1C(=O)C1CCCCC1,,CN(C)C=O,,[H-].[Na+],,test
US20140142083A1,CCN(c1cc(C2CN(C(=O)OC(C)(C)C)C2)cc(C(=O)OC)c1C)C1CCOCC1>>CCN(c1cc(C2CN(C(=O)OC(C)(C)C)C2)cc(C(=O)O)c1C)C1CCOCC1,,C1CCOC1,CO,[Na+].[OH-],,test
US20080085886A1,CCOC(=O)c1oc2ccncc2c1Oc1ccc([N+](=O)[O-])cc1F>>CCOC(=O)c1oc2ccncc2c1Oc1ccc(N)cc1F,[Fe],CCO,Cl,,,test
US05696148,CS(=O)(=O)CC#N.Cn1c(Cl)c(C=O)c2ccccc21>>Cn1c(Cl)c(C=C(C#N)S(C)(=O)=O)c2ccccc21,,C1CCOC1,,CCN(CC)CC,,test
US20040229861A1,COc1ccc(CNc2cccnc2C#N)c(OC)c1>>COc1ccc(CNc2cccnc2CN)c(OC)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100120749A1,CC1CCCCN1CCN.O=C(O)c1ccc(-n2c(-c3ccccc3)cc3c2CCCC3)cc1>>CC1CCCCN1CCNC(=O)c1ccc(-n2c(-c3ccccc3)cc3c2CCCC3)cc1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20040204427A1,CC(C)(C)O.COc1cc(C(=O)O)ccc1F.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COc1cc(NC(=O)OC(C)(C)C)ccc1F,,Cc1ccccc1,,CCN(CC)CC,,test
US04036842,CCCl.CNC.c1ccc2c3c(sc2c1)COCC3>>CN(C)CCC1OCCc2c1sc1ccccc21,,C1COCCO1,,,,test
US20030186969A1,CCOC(=O)CNCc1cc(C(=O)OC)ccc1[N+](=O)[O-].O=C(O)c1ccc(Cl)cc1>>COC(=O)c1ccc(N)c(CNCC(=O)OCCC(=O)c2ccc(Cl)cc2)c1,[Pd],CCOC(C)=O,ClCCl,CCN(CC)CC,[H][H],test
US05506267,CCCCCCCCCCCCCCCC(=O)OCC(CSCCC(=O)N[C@@H](CCCNC(=O)OC(C)(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H](CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)OC(=O)CCCCCCCCCCCCCCC.Cl>>CCCCCCCCCCCCCCCC(=O)OCC(CSCCC(=O)N[C@@H](CCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)O)OC(=O)CCCCCCCCCCCCCCC.Cl,,CC(=O)O,,,,test
US04923857,C=CCOC(=O)C(N1C(=O)[C@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)[C@H]1[C@@H](C)C(C)=O)=P(c1ccccc1)(c1ccccc1)c1ccccc1.C=CCOC(=O)N1CCC[C@H]1C=O>>C=CCOC(=O)C(N1C(=O)[C@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)[C@H]1[C@@H](C)C(=O)CC(O)[C@@H]1CCCN1C(=O)OCC=C)=P(c1ccccc1)(c1ccccc1)c1ccccc1,,C1CCOC1,CCOC(C)=O,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US06498251B1,CC(C)(C)OC(=O)N1CCc2sc(C(N)=O)cc2C1>>NC(=O)c1cc2c(s1)CCNC2,,CO,Cl,,,test
US20080188506A1,N#Cc1cccc(N=C=O)c1.O=C1Nc2cc(Cl)ccc2C12C(c1ccc(Cl)cc1)CCNC2c1cccc(F)c1>>N#Cc1cccc(NC(=O)N2CCC(c3ccc(Cl)cc3)C3(C(=O)Nc4cc(Cl)ccc43)C2c2cccc(F)c2)c1,,ClCCl,,,,test
US05403851,NCCc1c[nH]c2ccccc12.O=C(n1ccnc1)n1ccnc1.OCC1CC1>>O=C(NCCc1c[nH]c2ccccc12)OCC1CC1,,C1CCOC1,,CCCCCC,CCOC(C)=O,test
US20040067930A1,CCOC(=O)C1(CC[N+](=O)[O-])CCCN1Cc1ccccc1>>O=C1NCCC12CCCN2Cc1ccccc1,[Ni],CCO,,,,test
US05310757,C[C@@H]1C[C@H](O)CC(C)(C)C1.Cc1ccc(C)c(OCCCC(C)(C)C(=O)Cl)c1>>Cc1ccc(C)c(OCCCC(C)(C)C(=O)O[C@H]2C[C@@H](C)CC(C)(C)C2)c1,,Cc1ccccc1,,,,test
US20120010228A1,COC(=O)c1ccc(N2CN(c3ccccc3)C3(CCN(C(=O)OCc4ccccc4)CC3)C2=O)cc1>>O=C(O)c1ccc(N2CN(c3ccccc3)C3(CCN(C(=O)OCc4ccccc4)CC3)C2=O)cc1,,CO,O,[Li+].[OH-],,test
US06235680B1,COc1ccccc1C(=O)Cl.NS(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)cc2Cl)cc1>>COc1ccccc1C(=O)NS(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)cc2Cl)cc1,CN(C)c1ccncc1,CC#N,,CCN(CC)CC,O,test
US20090023753A1,NCCO.O=C(Nc1ccc2c(c1)OC(F)(F)O2)c1scnc1NCc1ccnc(Cl)c1>>O=C(Nc1ccc2c(c1)OC(F)(F)O2)c1scnc1NCc1ccnc(NCCO)c1,,O,c1ccncc1,,,test
US20070264505A1,BrC(Br)(Br)Br.CC(C)(C)OC(=O)COCCOCCOCCOCCOCCOCCO>>CC(C)(C)OC(=O)COCCOCCOCCOCCOCCOCCBr,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090023737A1,CCCc1cc(N)nnc1Cn1ccnc1-c1cccc(F)n1.CCOC(=O)C(=O)CBr>>CCCc1cc2nc(C(=O)OCC)cn2nc1Cn1ccnc1-c1cccc(F)n1,,CN(C)C=O,,,,test
US20030105151A1,CCOc1cccc(-c2ccc3c(c2)NC(=O)C3)c1.Cc1[nH]c(C=O)c(C)c1CCC(=O)O>>CCOc1cccc(-c2ccc3c(c2)NC(=O)C3=Cc2[nH]c(C)c(CCC(=O)O)c2C)c1,C1CCNCC1,CCO,,,,test
US06225316B1,CNC(=O)c1ccncc1I.Cc1ccccc1B(O)O>>CNC(=O)c1ccncc1-c1ccccc1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20100313782A1,CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O.NC=O>>CC(C)(C)c1cc(CNC=O)cc(C(C)(C)C)c1O,,O,,O=C[O-].[NH4+],,test
US20070203133A1,COCc1nc2nc(-c3ncccc3C(F)(F)F)ccc2c(Nc2ccc(C(F)(F)F)cc2O)c1[N+](=O)[O-]>>COCc1nc2nc(-c3ncccc3C(F)(F)F)ccc2c2c1Oc1cc(C(F)(F)F)ccc1N2,,CC(=O)N(C)C,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20120157430A1,COc1c(C(C)=O)cc(Cl)c(C)c1-c1cn[nH]c1.N#CCCl>>COc1c(C(C)=O)cc(Cl)c(C)c1-c1cnn(CC#N)c1,,CN(C)C=O,,[H-].[Na+],,test
US04550105,CO/N=C(\C(=O)Cl)c1csc(NC(=O)CCl)n1.N[C@@H]1C(=O)N[C@@H]1CO>>CON=C(C(=O)N[C@@H]1C(=O)N[C@@H]1CO)c1csc(NC(=O)CCl)n1,,C1CCOC1,O,Cl,O=C([O-])O.[Na+],test
US04323570,CC(=O)N1CCN=C1C1=C(Cl)N(N)C(C)N=C1Cl.CO>>COC1=C(C2=NCCN2)C(Cl)=NC(C)N1N,,CO,,O,C[O-].[Na+],test
US20110319394A1,CCn1c(=O)n(-c2ccc(O)cc2)c2ncccc21.Cn1c(S(C)(=O)=O)nc2c1CCCC2>>CCn1c(=O)n(-c2ccc(Oc3nc4c(n3C)CCCC4)cc2)c2ncccc21,,CC(=O)N(C)C,,O,[H-].[Na+],test
US20020137769A1,CC(=O)c1cccc2ccccc12.COC(=O)OC>>COC(=O)CC(=O)c1cccc2ccccc12,,CCCCCC,CCOC(C)=O,[H-].[Na+],,test
US20150336960A1,CC1CC(c2ccncc2[N+](=O)[O-])=CC2C1OC(=O)N2C(=O)OC(C)(C)C>>C[C@H]1CC(c2ccncc2[N+](=O)[O-])=C[C@@H](NC(=O)OC(C)(C)C)[C@H]1O,,C1CCOC1,CCOC(C)=O,[Li+].[OH-],,test
US20160272628A1,COC(=O)C1NS(=O)(=O)c2ccc(-c3cn(C(=O)OC(C)(C)C)c4cc(F)ccc34)cc21.N>>CC(C)(C)OC(=O)n1cc(-c2ccc3c(c2)C(C(N)=O)NS3(=O)=O)c2ccc(F)cc21,,CCO,,,,test
US20160075663A1,CCOC(=O)CBr.O=C1CCCC1>>CCOC(=O)CC1(O)CCCC1,[Zn],CCOCC,,C[Si](C)(C)Cl,,test
US20130029961A1,CC(C)(C)OC(=O)NCc1ccc(C(F)(F)F)nc1-c1ccc(F)c(Cl)c1.Cl>>Cl.NCc1ccc(C(F)(F)F)nc1-c1ccc(F)c(Cl)c1,,C1COCCO1,,,,test
US20050101643A1,CC[C@H](CO)Cc1ccc(F)cc1F.CS(=O)(=O)Cl>>CC[C@H](COS(C)(=O)=O)Cc1ccc(F)cc1F,,ClCCl,,CCN(CC)CC,,test
US20080113963A1,Cc1nc2c3c(c(C(=O)O)cc2n1C)CCC(c1ccccc1)O3.OC1CCNC1>>Cc1nc2c3c(c(C(=O)N4CCC(O)C4)cc2n1C)CCC(c1ccccc1)O3,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US09243002B2,CCOC(=O)/C=C/c1ccc(Cl)nc1Cl>>CCOC(=O)CCc1ccc(Cl)nc1Cl,[Pt],CCO,,,,test
US20010039285A1,COc1cccc(CCNC(=O)C2CCN(C(=O)C(F)(F)F)CC2)c1>>COc1ccc2c(c1)CCN=C2C1CCN(C(=O)C(F)(F)F)CC1,,O=P(Cl)(Cl)Cl,,,,test
US20100150827A1,CCOC(=O)/C=C/c1c(C)nc(SC)nc1NC1CCOC1>>CSc1nc(C)c2ccc(=O)n(C3CCOC3)c2n1,,CCN(C(C)C)C(C)C,,C1CCC2=NCCCN2CC1,,test
US20100226881A1,CI.Oc1ccn2nccc2c1>>COc1ccn2nccc2c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20030187026A1,CC(=N)N.O=Cc1ccc(Br)cc1F>>Cc1ncc2ccc(Br)cc2n1,,CC(=O)N(C)C,,,,test
US20090156578A1,CC(=O)c1oc2ccccc2c1C.CC(C)(C)[S@](N)=O>>CC(=N[S@](=O)C(C)(C)C)c1oc2ccccc2c1C,,C1CCOC1,,[Cl-].[Na+],,test
US20110263658A1,CC(C)OB(OC(C)C)OC(C)C.COCCc1ccccc1Br>>COCCc1ccccc1B(O)O,,C1CCOC1,,[Li]CCCC,,test
US05086062,CC1CCCC(C(=O)O)C1>>CC1CCCC(CO)C1,,C1CCOC1,CCOCC,,,test
US05260314,CCOC(=O)C(C#N)=C1CN2CCC1CC2>>CCOC(=O)C(C#N)C1CN2CCC1CC2,[Pd],CCO,,[H][H],,test
US20040199005A1,CC[C@@H]1CC(=O)N1c1ccc(C(F)(F)F)cc1.CO>>CC[C@H](CC(=O)OC)Nc1ccc(C(F)(F)F)cc1,,CO,,C[O-].[Na+],,test
US04467098,NC(N)=O.NNc1ccccc1.O=CO>>Oc1ncn(-c2ccccc2)n1,,Cc1ccccc1C,O,O=S(=O)(O)O,,test
US05434261,CC(C)(C)C1C=CC=CC1(Br)S(N)(=O)=O.Cc1ccc([Sn](C)(C)C)cc1>>Cc1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,,,test
US20090192138A1,COC(=O)c1c(Cl)n(COCC[Si](C)(C)C)c2c(=O)n(CC(=O)c3cccc(OC)c3)cnc12>>COC(=O)c1c(Cl)[nH]c2c(=O)n(CC(=O)c3cccc(OC)c3)cnc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070298104A1,CCCCOC(=O)c1nc(O)c2ccc(Oc3c(C)cccc3CC)cc2c1O.O=P(Br)(Br)Br>>CCCCOC(=O)c1nc(Br)c2ccc(Oc3c(C)cccc3CC)cc2c1O,,CC#N,,,,test
US20100168185A1,CCc1nc(-c2ccc(F)cc2)c(Br)s1.Cc1cc(B2OC(C)(C)C(C)(C)O2)ccn1>>CCc1nc(-c2ccc(F)cc2)c(-c2ccnc(C)c2)s1,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120053180A1,CCCCC(=O)Cl.CS(=O)(=O)c1ccc(-c2cc(F)c(OC3CCC(O)CC3)c(F)c2)cc1>>CCCCC(=O)OC1CCC(Oc2c(F)cc(-c3ccc(S(C)(=O)=O)cc3)cc2F)CC1,,CC#N,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20030144283A1,CCCCc1nc2c(N)nc3ccccc3c2n1CCCCN.O=C(Cl)c1ccccc1>>CCCCc1nc2c(N)nc3ccccc3c2n1CCCCNC(=O)c1ccccc1,,c1ccncc1,,,,test
US20060183763A1,C1CCOC1.CC(C)(C)OC(=O)N1CC(Oc2cnc3ccccc3n2)CC1C(=O)O.CN(C)C(=O)C1CC(Oc2cnc3ccccc3n2)CN1C(=O)OC(C)(C)C.CNC>>COc1cc2ncnc(N3CCC(OC4=NC5CCCCC5N=C4)C3)c2cc1OC,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US03944560,CC(C)N1CC2(COc3ccccc3OC2)OC1=O.O=[N+]([O-])O>>CC(C)N1CC2(COc3ccc([N+](=O)[O-])cc3OC2)OC1=O,,CC(=O)O,,O=S(=O)(O)O,,test
US20060247251A1,CC1(C)CCNC1=O.Oc1ccc(I)cc1>>CC1(C)CCN(c2ccc(O)cc2)C1=O,,C1COCCO1,,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US20040259923A1,CSc1ccc(-c2sc(NC(C)=O)nc2/C=C/c2ccc([N+](=O)[O-])cc2)cc1.O=S(=O)([O-])O[O-]>>CC(=O)Nc1nc(/C=C/c2ccc([N+](=O)[O-])cc2)c(-c2ccc(S(C)(=O)=O)cc2)s1,,C1CCOC1,,O,,test
US04414225,CCCN1CCc2cc(C(=O)OCC)sc2CC1.NN>>CCCN1CCc2cc(C(=O)NN)sc2CC1,,CCO,,O,,test
US20070142304A1,CC(C)(C)OC(=O)NCC(=O)O.N[C@H](CC1CCCCC1)C(=O)O>>NCC(=O)N[C@H](CC1CCCCC1)C(=O)O,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20080009490A1,CC(C)n1c(=O)c(O)c2n(c1=O)CCNC2=O.CO>>COc1c2n(c(=O)n(C(C)C)c1=O)CCNC2=O,,CCOCC,CO,C[Si](C)(C)C=[N+]=[N-],,test
US20140256926A1,CC(C)OC(=O)CCC1(CCCBr)OCCO1.CCCCP(CCCC)CCCC>>CCCC[P+](CCCC)(CCCC)CCCC1(CCC(=O)OC(C)C)OCCO1.[Br-],,CC#N,,,,test
US20100204196A1,CCN(CC)CC(=O)N1CCc2cc(OC)c(Nc3nc(Nc4cccc(F)c4C(N)=O)c4ccnc-4[nH]3)cc21.CN>>CCN(CC)CC(=O)N1CCc2cc(OC)c(Nc3nc(Nc4cccc(F)c4C(=O)NC)c4ccnc-4[nH]3)cc21,,C1CCOC1,,CO,C[O-].[Na+],test
US20140349993A1,CC1(C)OC[C@H](CCl)O1.COC(=O)c1cccc(O)c1>>COC(=O)c1cccc(OC[C@H]2COC(C)(C)O2)c1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20030119787A1,CC(C)C(NC(=O)CCc1ccccc1)[PH](=O)O[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OCc1ccccc1.O>>CC(C)C(NC(=O)CCc1ccccc1)P(=O)(O)O[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)OCc1ccccc1,,C1COCCO1,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20030073731A1,COc1cc2cc(C(=O)Nc3cc(OCc4ccccc4)c4ccccc4c3CCCl)[nH]c2c(OC)c1OC>>COc1cc2cc(C(=O)Nc3cc(O)c4ccccc4c3CCCl)[nH]c2c(OC)c1OC,[Pd],C1CCOC1,,,,test
US20070232632A1,CN=C=O.CS(=N)(=O)c1ccc([N+](=O)[O-])cc1>>CNC(=O)N=S(C)(=O)c1ccc([N+](=O)[O-])cc1,,Cc1ccccc1,,,,test
US05891871,COC(=O)Cc1cc2c(cc1C(=O)c1ccc([N+](=O)[O-])cc1)OCO2.NN>>O=C1Cc2cc3c(cc2C(c2ccc([N+](=O)[O-])cc2)=NN1)OCO3,,CCO,,CC(=O)O,O,test
US20090163512A1,Cc1ccc(S(=O)(=O)OCC2(C)COC2)cc1.O=Cc1cc(Cl)ccc1O>>CC1(COc2ccc(Cl)cc2C=O)COC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060063779A1,N#Cc1ccc(F)cc1Cl.O=C1CCCN1>>N#Cc1ccc(N2CCCC2=O)cc1Cl,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05420308,COc1cccc(C=O)c1O>>O=Cc1cccc(O)c1O,,CC(=O)O,,Br,,test
US04116951,CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)ON1C(=O)CCC1=O.C[C@@H](OCc1ccccc1)[C@H](N)C(=O)N[C@@H](COCc1ccccc1)C(=O)N[C@@H](COCc1ccccc1)C(=O)N[C@@H](CCC(=O)OCc1ccccc1)C(=O)O>>C[C@@H](OCc1ccccc1)[C@H](NC(=O)[C@H](CC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](COCc1ccccc1)C(=O)N[C@@H](COCc1ccccc1)C(=O)N[C@@H](CCC(=O)OCc1ccccc1)C(=O)O,,CN(C)C=O,,CCN(CC)CC,CS(C)=O,test
US20100035942A1,Cc1ccc(CO)c(OS(C)(=O)=O)c1.II>>Cc1ccc(CI)c(OS(C)(=O)=O)c1,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05891909,Cc1cc(NC(=O)C(C)(C)O)cc(OCc2ccccc2)c1>>Cc1cc(N)cc(OCc2ccccc2)c1,,O,,CCO,[Na+].[OH-],test
US20090215759A1,CC(C)O.COc1cc(Nc2nc(C)cc(Cl)n2)ccc1-n1cnc(C)c1>>COc1cc(Nc2nc(C)cc(OC(C)C)n2)ccc1-n1cnc(C)c1,,CC(C)O,,[Na],,test
US20080004309A1,CCOC(=O)CNC(=O)OC(C)(C)C.CCOC(=O)c1sc(N(C)c2ccccc2)nc1CBr>>CCOC(=O)CN(Cc1nc(N(C)c2ccccc2)sc1C(=O)OCC)C(=O)OC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20030092711A1,CC1OC(=O)Nc2ccc(-c3cccc(F)c3)cc21.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC1OC(=S)Nc2ccc(-c3cccc(F)c3)cc21,,Cc1ccccc1,,,,test
US20150210722A1,CC(C)(C)c1cc(C(=O)O)n(-c2cccc(CP3(=O)CCCC3)c2)n1.Nc1ccc(Oc2ccnc(Nc3ccccc3)c2)c2ccccc12.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccccc4)c3)c3ccccc23)n(-c2cccc(CP3(=O)CCCC3)c2)n1,,CN(C)C=O,,CC#N,,test
US20060217426A1,COC(=O)c1cc(C)sc1NC(=O)c1ccc(OC)c(OC)c1>>COc1ccc(C(N)=O)cc1OC,,CCO,,NN,,test
US20130085142A1,CC(C)(C)OC(=O)N1C[C@H](Oc2cnc(C3CC3)cn2)C[C@H]1CN=[N+]=[N-]>>[N-]=[N+]=NC[C@@H]1C[C@@H](Oc2cnc(C3CC3)cn2)CN1,,C1COCCO1,ClCCl,Cl,,test
US20030134854A1,CO.COc1ccc(-c2ccccc2)c2sc(NC(=O)c3ccnc(Br)c3)nc12>>COc1cc(C(=O)Nc2nc3c(OC)ccc(-c4ccccc4)c3s2)ccn1,,C1COCCO1,,[H-].[Na+],,test
US20160083365A1,COC(=O)CS(C)(=O)=O.CSc1nccc(Cl)n1>>COC(=O)C(c1ccnc(SC)n1)S(C)(=O)=O,,CN(C)C=O,,Cl,[H-].[Na+],test
US05686445,O=C(c1ccc([N+](=O)[O-])cc1)N1Cc2ccccc2Cc2cc(Cl)ccc21>>Nc1ccc(C(=O)N2Cc3ccccc3Cc3cc(Cl)ccc32)cc1,[Pd],CCO,CCOC(C)=O,[H][H],,test
US20110294807A1,COC(=O)c1ccc(NC(=O)c2ccccc2N)cc1.Cc1cc(C=O)cc(C)c1OCCO[Si](C)(C)C(C)(C)C>>COC(=O)c1ccc(-n2c(-c3cc(C)c(OCCO)c(C)c3)nc3ccccc3c2=O)cc1,,CCO,,,,test
US20010004669A1,CN1CCN(c2cccc3ccc(N)cc23)CC1.O=[N+]([O-])c1ccc(Cl)c([N+](=O)[O-])c1>>CN1CCN(c2cccc3ccc(Nc4ccc([N+](=O)[O-])cc4[N+](=O)[O-])cc23)CC1,,CN(C)C=O,,,,test
US20140228368A1,CCN(CC)S(F)(F)F.OCc1ccc(Br)nc1>>FCc1ccc(Br)nc1,,ClCCl,,,,test
US04187099,CC(C)N.O=C(Cl)c1csnc1-c1cccc(C(F)(F)F)c1>>CC(C)NC(=O)c1csnc1-c1cccc(C(F)(F)F)c1,,C1CCOC1,,,,test
US05534518,Brc1cccc(Br)c1.Oc1ccc(Cl)cc1>>Clc1ccc(Oc2cccc(Br)c2)cc1,,COCCOCCOC,,C[O-].[Na+],,test
US06239131B1,COC(=O)c1cc(N)ccc1Cl.Cc1ccc2c(c1)N(CC(=O)c1ccccc1C)C(=O)C(N)CN2C(=O)C(C)(C)C.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COC(=O)c1cc(NC(=O)NC2CN(C(=O)C(C)(C)C)c3ccc(C)cc3N(CC(=O)c3ccccc3C)C2=O)ccc1Cl,,C1CCOC1,O,CCN(CC)CC,,test
US20140371199A1,N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)O)cc4)cn23)cc1.c1ccc(N2CCNCC2)cc1>>N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)N5CCN(c6ccccc6)CC5)cc4)cn23)cc1,,CN(C)C=O,O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05686445,Cc1ccccc1C(=O)Cl.Nc1ccc(C(=O)N2Cc3ccccc3Cc3ccccc32)c(Cl)c1>>Cc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3ccccc3Cc3ccccc32)c(Cl)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04734416,ClCC1CO1.O=C1CCc2c(O)ccc(Cl)c2N1>>O=C1CCc2c(OCC3CO3)ccc(Cl)c2N1,,CC(C)O,,O=C([O-])[O-].[K+].[K+],,test
US20090029958A1,C[C@H](COCC(=O)O)c1ccccc1.OCC1CCNCC1>>C[C@H](COCC(=O)N1CCC(CO)CC1)c1ccccc1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150073019A1,COc1ccccc1C1=NN(c2nc3ccccc3s2)C(=O)C1=CN(C)C>>COc1ccccc1C1=NN(c2nc3ccccc3s2)C(=O)C1=CN,,CCO,O,N,,test
US20070249579A1,Brc1nccnc1Br.c1c[nH]cn1>>Brc1cnc(-n2ccnc2)cn1,,C1CCOC1,,[H-].[Na+],,test
US05084085,COC(=O)C(C)Br.Cc1nn(-c2cc(Oc3ccc(O)cc3Cl)c(Cl)cc2Cl)c(=O)n1C(F)F>>COC(=O)C(C)Oc1ccc(Oc2cc(-n3nc(C)n(C(F)F)c3=O)c(Cl)cc2Cl)c(Cl)c1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090156610A1,C#C[Si](C)(C)C.Cc1cc(Oc2ccc(I)cc2C2NC(=O)CC(c3cccc(Cl)c3)C23C(=O)Nc2cc(Cl)ccc23)cc(C)n1>>C#Cc1ccc(Oc2cc(C)nc(C)c2)c(C2NC(=O)CC(c3cccc(Cl)c3)C23C(=O)Nc2cc(Cl)ccc23)c1,[Cu]I,CN(C)C=O,CO,CCN(CC)CC,[Na+].[OH-],test
US20080242704A1,CC(=O)c1ccc(C)c(Nc2ncc(-c3ccc(C#N)cc3)o2)c1.O=Cc1ccccc1>>Cc1ccc(C(=O)CCc2ccccc2)cc1Nc1ncc(-c2ccc(C#N)cc2)o1,,CCO,,[Na+].[OH-],,test
US20130150364A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](Nc2cc(-n3c(C(F)F)nc4ccccc43)nc(N3CCOCC3)n2)CC1.CC(C)CBr>>CC(C)CN(c1cc(-n2c(C(F)F)nc3ccccc32)nc(N2CCOCC2)n1)[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20130065859A1,COC(=O)CC(=O)c1ccccc1C.Fc1ccc(Br)cc1CBr>>Cc1ccccc1C(=O)CCc1cc(Br)ccc1F,,C1CCOC1,,[H-].[Na+],,test
US20060154931A1,BrBr.O=C(Cc1ccncc1)c1ccc(OCc2ccccc2)cc1>>O=C(c1ccc(OCc2ccccc2)cc1)C(Br)c1ccncc1,,CC(=O)O,,,,test
US20120202785A1,C[C@H](N)c1nc2ccc(F)cc2n1[C@@H]1C[C@@H](OCc2ccccc2)C1.Clc1ncnc2c1ncn2C1CCCCO1>>C[C@H](Nc1ncnc2[nH]cnc12)c1nc2ccc(F)cc2n1[C@@H]1C[C@@H](OCc2ccccc2)C1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US04593092,CC1CCc2cccc3c2N1C(=O)C3=O.O=S(=O)(Cl)Cl>>CC1CCc2cc(Cl)cc3c2N1C(=O)C3=O,,ClC(Cl)(Cl)Cl,,,,test
US20120208827A1,Cc1cccc(NC[C@@H]2CCN(C(=O)C3CC3)C2)c1[N+](=O)[O-]>>Cc1cccc(NC[C@@H]2CCN(C(=O)C3CC3)C2)c1N,[Pd],CCO,,,,test
US04377522,CN1C(=O)C(C)(C)N=C(c2ccccc2F)c2cc(N)c(Cl)c(Cl)c21>>CN1C(=O)C(C)(C)N=C(c2ccccc2F)c2cc(N)cc(Cl)c21,,CCOCC,,,,test
US20110288067A1,CC(C)(CO)CNC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(C3CC3)nc12.CS(=O)(=O)Cl>>CC(C)(CNC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(C3CC3)nc12)COS(C)(=O)=O,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,Cl,test
US04666502,CCOCCNc1c(OC)csc1C.O=C(Cl)CCl>>CCOCCN(C(=O)CCl)c1c(OC)csc1C,,ClCCl,,O,O=C([O-])[O-].[K+].[K+],test
US05455339,Nc1ncnc2c1ncn2[C@H]1C=C[C@@H](CO)O1>>Nc1ncnc2c1ncn2[C@H]1CC[C@@H](CO)O1,[Pd],CO,,,,test
US20150031668A1,COC(=O)C[C@](N[S@](=O)C(C)(C)C)(c1ccc(OC(F)(F)F)c(F)c1)c1ncccc1F>>CC(C)(C)[S@@](=O)N[C@@](CCO)(c1ccc(OC(F)(F)F)c(F)c1)c1ncccc1F,,C1CCOC1,,[BH4-].[Li+],,test
US20140194469A1,BrCc1ccccc1.Cc1cc(O)n(-c2cc(C#N)ccn2)n1>>Cc1cc(OCc2ccccc2)n(-c2cc(C#N)ccn2)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100009978A1,CC(=O)Cl.COc1cc(Nc2nc3cccc(-c4ccc(CN)cc4)c3o2)cc(OC)c1OC>>COc1cc(Nc2nc3cccc(-c4ccc(CNC(C)=O)cc4)c3o2)cc(OC)c1OC,,c1ccncc1,,,,test
US20140199263A1,COc1ncc(Br)cc1C(N)=S.O=C1CCC(Br)C(=O)N1>>COc1ncc(Br)cc1-c1nc2c(s1)CCC(=O)N2,,CCO,,,,test
US20100160302A1,N#C[C@@H]1CCCN1C(=O)CCl.NC12CC3CC1CC(CN1C(=O)c4ccccc4C1=O)(C3)C2>>N#C[C@@H]1CCCN1C(=O)CNC12CC3CC1CC(CN1C(=O)c4ccccc4C1=O)(C3)C2,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20110172187A1,O=C(Nc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(Br)c1)C(F)(F)F>>Nc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(Br)c1,,CO,N,,,test
US20160194316A1,Cn1c(C(F)(F)F)c(C=O)c(=O)n1C.NO>>Cn1c(C(F)(F)F)c(C#N)c(=O)n1C,,CS(C)=O,,Cl,,test
US20090209524A1,CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC#N)cc1OC.CO.O=C([O-])O>>CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1OC,,CO,,O=S(=O)(O)O,,test
US20120088753A1,CC(C)(C)OC(=O)Nc1ccc(C(=O)N2CCOCC2)cc1>>Nc1ccc(C(=O)N2CCOCC2)cc1,,C1COCCO1,,Cl,,test
US20110251181A1,Brc1ccc2cc[nH]c2c1.O=[N+]([O-])/C=C/c1ccc(Cl)cc1>>O=[N+]([O-])CC(c1ccc(Cl)cc1)c1c[nH]c2cc(Br)ccc12,,CO,,,,test
US20050020605A1,CCON=C(c1ccc(Br)cc1)C1CCN(C2(C)CCNCC2)CC1.O=C(O)c1ccc2ccccc2n1>>CCON=C(c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3ccc4ccccc4n3)CC2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150141455A1,CC(C)(C)OC(=O)N[C@@H]1C[C@@]1(F)c1ccccc1.Cl>>Cl.N[C@@H]1C[C@@]1(F)c1ccccc1,,C1COCCO1,,,,test
US20100249123A1,CC(=O)NCC(C)(C)c1ccc(N)cc1-c1cccnc1.COc1ccc(C(=O)Cl)cc1OC>>COc1ccc(C(=O)Nc2ccc(C(C)(C)CNC(C)=O)c(-c3cccnc3)c2)cc1OC,,ClCCl,,CCN(CC)CC,,test
US20160222014A1,CC(C)(C)OC(=O)N1CCNCC1.O=[N+]([O-])c1ccc(F)cc1Cl>>CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)[O-])c(Cl)c2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160075711A1,CO.O=C(O)c1nc(Cl)ccc1Br>>COC(=O)c1nc(Cl)ccc1Br,O=S(=O)(O)O,O,,,,test
US20050080124A1,COc1ccc(N)cc1-c1c(Br)cnn1C.O=C=Nc1cccc2ccccc12>>COc1ccc(NC(=O)Nc2cccc3ccccc23)cc1-c1c(Br)cnn1C,,ClCCl,,,,test
US20030208079A1,COc1ccc2c(c1)CCOC2(C)C(F)(F)F>>CC1(C(F)(F)F)OCCc2cc(O)ccc21,,CC(=O)O,,Br,,test
US20070124152A1,COC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(-c2ccc(C(=O)N(C)C)cc2)c1=O.NCCN1CCOCC1>>CN(C)C(=O)c1ccc(-n2c(=O)c(C(=O)NCCN3CCOCC3)c(O)c3ncc(Cc4ccc(F)cc4)cc32)cc1,,CO,,,,test
US05498728,CCOC(=O)C(Cc1ccccc1)(Cc1ccc([N+](=O)[O-])cc1)C(=O)OCC>>O=C(O)C(Cc1ccccc1)Cc1ccc([N+](=O)[O-])cc1,,CCO,,O,[K+].[OH-],test
US20160108035A1,CCOC(=O)C1(Sc2ccnc3ccc(COC(C)=O)cc23)CCC1>>O=C(O)C1(Sc2ccnc3ccc(CO)cc23)CCC1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US04272437,CCC(CC(=O)OC(C)(C)C)N=[N+]=[N-]>>CCC(CC(=O)O)N=[N+]=[N-],,O=C(O)C(F)(F)F,,,,test
US03987047,Cc1c2c(nc3ccccc13)CCNCC2.Clc1ccccc1.O=S(=O)(O)Cl>>Cc1c2c(nc3ccccc13)CCN(S(=O)(=O)c1ccc(Cl)cc1)CC2,,c1ccncc1,,,,test
US20150336953A1,C#CCNc1nc(SC)nc(Cl)c1Br.O=C(OO)c1cccc(Cl)c1>>C#CCNc1nc(S(C)=O)nc(Cl)c1Br,,ClCCl,,,,test
US20110201640A1,C/C(C#N)=C1\c2ccccc2COc2cc(CO)ccc21.Cc1cc(C)c2nc(C)[nH]c2n1>>C/C(C#N)=C1\c2ccccc2COc2cc(Cn3c(C)nc4c(C)cc(C)nc43)ccc21,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160122341A1,CCOC(=O)c1c(C)nc2c(OCc3c(F)cccc3F)cc(C)cn12.NN>>Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(C(=O)NN)n2c1,,CCO,,O,O,test
US20100331335A1,C1CCOC1.CN(C)C=O.O=c1ccc2cc(C(F)(F)F)ccc2[nH]1>>CCOC(=O)Cn1c(=O)ccc2cc(C(F)(F)F)ccc21,,C1CCOC1,,[H-].[Na+],,test
US20070010671A1,CN(C)c1nc(N[C@@H]2CC[C@H](N)CC2)nc2ccccc12.O=C(Br)CBr>>CN(C)c1nc(N[C@@H]2CC[C@H](NC(=O)CBr)CC2)nc2ccccc12,,ClCCl,,,,test
US20040082651A1,CC(=CCCl)CCC=C(C)COC1CCCCO1.CC(=O)OC(C(C)=O)C(=O)OC(C)(C)C>>CC(=O)OC(CC=C(C)CCC=C(C)COC1CCCCO1)(C(C)=O)C(=O)OC(C)(C)C,,CN(C)C=O,,[H][H],[H-].[Na+],test
US20110312930A1,Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1ccc(NC(=O)OC(C)(C)C)cc1.ClCCN1CCCC1>>Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1ccc(N(CCN2CCCC2)C(=O)OC(C)(C)C)cc1,,CN(C)C=O,CO,Cl,[H-].[Na+],test
US20130085143A1,COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cc1cc(C)cc(C)c1>>Cc1cc(C)cc(CC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)O)c1,,CO,,O,[Li+].[OH-],test
US20100298373A1,CCCCOC(=O)/C=C/c1ccc(OC)c(C)c1CCNC(=O)OC(C)(C)C>>CCCCOC(=O)CC1NCCc2c1ccc(OC)c2C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150148332A1,CCN(c1nc(/C=C/c2nc3c(C)ncc(C)n3n2)n(C)n1)C1CC1>>CCN(c1nc(CCc2nc3c(C)ncc(C)n3n2)n(C)n1)C1CC1,[Pd],CO,,,,test
US20150353537A1,CC(C)(C)OC(=O)N1CC(C)(C)c2ccc(Cc3ccc(F)cc3)cc21.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N1CC(C)(C)c2cc(Br)c(Cc3ccc(F)cc3)cc21,,CC#N,,,,test
US04439365,CC(=O)O.CCOC(=O)CCCCCCC1CCCC1=O>>CCOC(=O)CCCCCCC1=C(OC(C)=O)CCC1,,CC(=O)OC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US06310095B1,COC(=O)[C@@H](N)CCSC.O=C(Cl)c1ccc(CCl)cc1>>COC(=O)[C@H](CCSC)NC(=O)c1ccc(CCl)cc1,,ClC(Cl)Cl,,Cl,c1ccncc1,test
US05019578,CC1(NC[C@H](O)c2ccc3nnnn3c2)CCCC1.Cl.Cl[Sn]Cl>>CC1(NCC(O)c2ccc(N)nc2)CCCC1.Cl.Cl,,CO,,,,test
US04014677,CCc1nc(Cl)c([N+](=O)[O-])c(NC(C)C)n1.SC1CCCCC1>>CCc1nc(NC(C)C)c([N+](=O)[O-])c(SC2CCCCC2)n1,,CCN(CC)CC,,,,test
US20160200695A1,Br[Mg]c1ccccc1.COC(=O)c1ccc(/C=N/[S@@](=O)C(C)(C)C)cc1>>COC(=O)c1ccc([C@H](N[S@@](=O)C(C)(C)C)c2ccccc2)cc1,,CCOCC,ClCCl,,,test
US04182727,COc1ccc(OCCOCCCl)c(Cl)c1.[I-]>>COc1ccc(OCCOCCI)c(Cl)c1,,CCC(C)=O,,[Cl-].[Na+],,test
US20030186969A1,CCOC(=O)c1ccc2c(c1)N(Cc1ccc(C3=NCCN3C)cc1)C(=O)CN(C(=O)c1ccc(Cl)cc1)C2.CI.O=C(O)C(F)(F)F>>CCOC(=O)c1ccc2c(c1)N(Cc1ccc(C3=[N+](C)CCN3C)cc1)C(=O)CN(C(=O)c1ccc(Cl)cc1)C2.O=C([O-])C(F)(F)F,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05175166,CCC(N)=NO.COC(=O)C1CN=CN(C(c2ccccc2)(c2ccccc2)c2ccccc2)C1>>CCc1noc(C2CN=CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)C2)n1,,C1CCOC1,,[H-].[Na+],,test
US04431653,O=CN1CCC(CCCn2ccnc2)CC1>>c1cn(CCCC2CCNCC2)cn1,,C1COCCO1,,,,test
US05534520,CC(=O)NC1(CO)CCN(C)CC1>>CCNC1(CO)CCN(C)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06506751B1,O=C1CSC(c2cccc(Cl)c2)N1CCCN1CCCCC1.O=Cc1cccc(Cl)c1>>O=C1C(=Cc2cccc(Cl)c2)SC(c2cccc(Cl)c2)N1CCCN1CCCCC1,,Cc1ccccc1,,CC(C)(C)[O-].[K+],,test
US20100168418A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc2ncc(=O)n(CCN3CCC(NCc4nc5c(cc4Cl)SCC(=O)N5)CC3)c2c1>>COc1ccc2ncc(=O)n(CCN3CCC(N(Cc4nc5c(cc4Cl)SCC(=O)N5)C(=O)OC(C)(C)C)CC3)c2c1,,CCN(CC)CC,,ClC(Cl)Cl,,test
US04710509,Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)Cl.c1c[nH]cn1>>Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)n1ccnc1,,c1ccncc1,,O,,test
US20070232649A1,O=C(O)CS(=O)(=O)Nc1ccc(Br)cc1.O=Cc1cccc(Br)c1O>>O=c1oc2c(Br)cccc2cc1S(=O)(=O)Nc1ccc(Br)cc1,,CC(=O)O,,,,test
US20100216814A1,CC(=CBr)c1ccncc1.Cc1ccc2[nH]c3c(c2c1)CN(C)C(C)C3>>C/C(=C\n1c2c(c3cc(C)ccc31)CN(C)C(C)C2)c1ccncc1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20100016371A1,CC(C)(C)OC(=O)n1cc(C(=O)C(F)(F)F)c2ccc(Cl)cc21>>CC(C)(C)OC(=O)n1cc(C(O)C(F)(F)F)c2ccc(Cl)cc21,,CCO,,[BH4-].[Na+],,test
US20150038510A1,CC(=O)Cl.CCc1ccccc1N>>CCc1ccccc1NC(C)=O,,O,,CCN(CC)CC,ClCCl,test
US20090156604A1,COC(=O)c1ccc(-c2nc3scnn3c2-c2ccccc2)cc1>>OCc1ccc(-c2nc3scnn3c2-c2ccccc2)cc1,,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US20070054891A1,CC(C)(C)N=C=O.Clc1ccc(C(OC2CNC2)c2ccc(Cl)cc2Cl)cc1>>CC(C)(C)NC(=O)N1CC(OC(c2ccc(Cl)cc2)c2ccc(Cl)cc2Cl)C1,,ClCCl,,CCN(CC)CC,,test
US03974154,COC(=O)C(O)N1C(=O)C(NC(c2ccccc2)(c2ccccc2)c2ccccc2)C1SCC#Cc1ccccc1.O=S(Cl)Cl>>COC(=O)C(Cl)N1C(=O)C(NC(c2ccccc2)(c2ccccc2)c2ccccc2)C1SCC#Cc1ccccc1,,C1CCOC1,C1COCCO1,c1ccncc1,,test
US20010053853A1,C#CCCC(=O)OCCCC.COc1ccc(CNc2cccc(Br)n2)cc1>>CCCCOC(=O)CCC#Cc1cccc(NCc2ccc(OC)cc2)n1,[Cu]I,CCN(CC)CC,,,,test
US20090170926A1,O=C1C=Cc2c(ccc3c2C=CC(c2ccccc2)(c2ccccc2)O3)C1=O.[OH-]>>O=C1C(O)=CC(=O)c2c1ccc1c2C=CC(c2ccccc2)(c2ccccc2)O1,,CCO,,Cl,,test
US20060019965A1,C[Mg]Br.O=Cc1ccc2nccnc2c1>>CC(O)c1ccc2nccnc2c1,,C1CCOC1,,,,test
US20140031364A1,COc1cccc(N2CCNCC2)c1.Nc1onc(-c2ccc(OC(F)(F)F)cc2)c1C(=O)O>>COc1cccc(N2CCN(C(=O)c3c(-c4ccc(OC(F)(F)F)cc4)noc3N)CC2)c1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20090143421A1,Nc1ccc(Cl)cn1.O=C(CBr)C(=O)c1ccccc1>>Br.O=C(c1ccccc1)c1cn2cc(Cl)ccc2n1,,CN(C)C=O,,,,test
US20150282482A1,C#Cc1ccc2cc(C(=O)O)sc2c1.CO>>C#Cc1ccc2cc(C(=O)OC)sc2c1,,CO,,C[Si](C)(C)C=[N+]=[N-],,test
US20050032849A1,CCCCCOc1ccc([N+](=O)[O-])cc1C(F)(F)F>>CCCCCOc1ccc(N)cc1C(F)(F)F,[Pd],CCO,,[H][H],,test
US20050239766A1,Fc1ccc(S)cc1.O=C1C(CCCl)C(c2ccc(O)cc2)N1c1ccc(F)cc1>>O=C1C(CCSc2ccc(F)cc2)C(c2ccc(O)cc2)N1c1ccc(F)cc1,,CC#N,,CCN(CC)CC,,test
US05066795,FC(F)(F)Sc1ccccc1-c1ccccc1.O=C(OO)c1cccc(Cl)c1>>O=S(c1ccccc1-c1ccccc1)C(F)(F)F,,ClCCl,,,,test
US06248756B1,COC(=O)C1CCN(C(=O)OC(C)(C)C)CC1.Cc1cccc(CBr)c1>>COC(=O)C1(Cc2cccc(C)c2)CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US05106871,COC(=O)CBr.COc1cc(OC)c(C(C)=O)c(O)c1CCC(C)C>>COC(=O)COc1c(CCC(C)C)c(OC)cc(OC)c1C(C)=O,,CN(C)C=O,,Cl,[H-].[Na+],test
US20130178461A1,CC(C)(C)OC(=O)N1CC2(C1)CN(c1ccc([N+](=O)[O-])nc1)C2>>CC(C)(C)OC(=O)N1CC2(C1)CN(c1ccc(N)nc1)C2,[Pd],CO,,CCOC(C)=O,,test
US04956333,Cc1cc(C)c(S(=O)(=O)Cl)c(C)c1.Oc1ccccc1>>Cc1cc(C)c(S(=O)(=O)Oc2ccccc2)c(C)c1,,Cc1ccccc1,,O,[Na+].[OH-],test
US05302595,CNCCc1ccc(F)cc1.N#CC(CCBr)(c1ccccc1)c1ccccc1>>CN(CCc1ccc(F)cc1)CCC(C#N)(c1ccccc1)c1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05648367,Cc1nccn1CCCC(=O)c1ccc(F)cc1.Cl.Cl.NCCON>>Cc1nccn1CCCC(=NOCCN)c1ccc(F)cc1.Cl.Cl,,CCO,,c1ccncc1,,test
US20110224262A1,Cc1cc(-c2ccccc2)n[nH]1.II>>Cc1n[nH]c(-c2ccccc2)c1I,,C1CCOC1,O,[I-].[K+],O=C([O-])O.[Na+],test
US20110028455A1,Cc1[nH]cc(C(N)=O)c(=O)c1Br.O=P(Cl)(Cl)Cl>>Cc1ncc(C#N)c(Cl)c1Br,CN(C)C=O,,,,,test
US04146715,CCO.C[Si](C)(C)c1nc2nc(N([Si](C)(C)C)[Si](C)(C)C)[nH]c(=O)c2[nH]1.O=C1c2ccccc2C(=O)N1CCOCCl>>Nc1nc2c(ncn2COCCN2C(=O)c3ccccc3C2=O)c(=O)[nH]1.O,,CCO,Cc1ccccc1,CCN(CC)CC,,test
US20060135503A1,N#Cc1cc(C(F)(F)F)ccc1F.NN>>Nc1n[nH]c2ccc(C(F)(F)F)cc12,,CCCCO,,O,,test
US06277850B1,CCOC(=O)c1ccc(NC(=O)NCc2ccn(-c3cc4[nH]c(=O)c(=O)[nH]c4cc3C(F)(F)F)c2)cc1>>O=C(NCc1ccn(-c2cc3[nH]c(=O)c(=O)[nH]c3cc2C(F)(F)F)c1)Nc1ccc(C(=O)O)cc1,,O,,[Li+].[OH-],,test
US20160060197A1,CC[C@H](C)c1cccc([C@H](C)C2CC2)c1O.ClCBr>>CC[C@H](C)c1cccc([C@H](C)C2CC2)c1OCCl,,C1CCOC1,,[Na+].[OH-],,test
US06177154B1,CCCc1ccc(C(=S)S)cc1.O=S(Cl)Cl>>CCCc1ccc(C(=S)Cl)cc1,,CCOCC,,,,test
US04224325,CNN.Cc1cc(C)n(-c2ccc(Cl)nn2)n1>>Cc1cc(C)n(-c2ccc(N(C)N)nn2)n1,,O,,CCO,,test
US20100190768A1,COCOC(C(=O)N1CCC(Oc2ccc(CC(=O)O)cc2OC)CC1)(c1cn(Cc2ccccc2)c2cc([N+](=O)[O-])ccc12)C(F)(F)F>>COc1cc(CC(=O)O)ccc1OC1CCN(C(=O)C(O)(c2cn(Cc3ccccc3)c3cc([N+](=O)[O-])ccc23)C(F)(F)F)CC1,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20020040146A1,O=C(Cl)OCc1ccccc1.[N-]=[N+]=NC[C@@H]1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1>>NC[C@@H]1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1C(=O)OCc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20060084673A1,Cc1ccccc1CBr.NC1=NC(=O)CN1C(=O)OCc1ccccc1>>Cc1ccccc1CNC1=NC(=O)CN1C(=O)OCc1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04452738,N#CN1c2ccccc2C=C([N+](=O)[O-])c2ccccc21.O>>NC(=O)N1c2ccccc2C=C([N+](=O)[O-])c2ccccc21,,CC(=O)O,ClC(Cl)Cl,O=S(=O)(O)O,,test
US20110160198A1,Clc1ccc(CBr)cc1Cl.O=CC(=O)c1ccc(O)cc1>>O=CC(=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05688795,CS(=O)(=O)Cl.Cc1ccc(NCCCN2CCN(c3ccccc3N)CC2)c(C(=O)N(C)C)c1>>Cc1ccc(NCCCN2CCN(c3ccccc3NS(C)(=O)=O)CC2)c(C(=O)N(C)C)c1.Cl,,c1ccncc1,,,,test
US20140056928A1,C1CCNC1.CCCCc1nc(NCc2ccc(OC)c(OC)c2)c2[nH]nc(C#CCCCCCl)c2n1>>CCCCc1nc(NCc2ccc(OC)c(OC)c2)c2[nH]nc(C#CCCCCN3CCCC3)c2n1,,CC#N,,CCN(CC)CC,,test
US20150175602A1,CO[C@H](C)C(=O)O.Fc1ccc(OC2CCN(c3nc4c(nc3NCC(F)F)CNCC4)CC2)c(F)c1.O=C(O)C(F)(F)F>>CO[C@H](C)C(=O)N1CCc2nc(N3CCC(Oc4ccc(F)cc4F)CC3)c(NCC(F)F)nc2C1.O=C(O)C(F)(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040180934A1,COC(=O)CC1CCn2c1cc1c(Br)cc(F)cc12.O=CCc1ccc(Cl)cc1>>COC(=O)CC1CCn2c1c(CCc1ccc(Cl)cc1)c1c(Br)cc(F)cc12,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20100130738A1,BrBr.CCc1ccc2cccc(OC)c2n1>>CCc1ccc2c(Br)ccc(OC)c2n1,,CO,,O=C([O-])O.[Na+],,test
US20090253687A1,Nn1cnnc1S.O=C1COc2ccc(C(=O)C(Br)c3ccccc3Cl)cc2N1>>O=C1COc2ccc(C3=Nn4cnnc4SC3c3ccccc3Cl)cc2N1,,Cc1ccccc1,,CCO,,test
US20010016579A1,CN1CCCNCC1.Sc1nc2c(ccc3ccccc32)o1>>CN1CCCN(c2nc3c(ccc4ccccc43)o2)CC1,,ClC(Cl)Cl,,,,test
US04143047,CCNC(C)=O.Cc1coc(S(=O)Cc2ccccc2)n1>>CCN(C(C)=O)c1nc(C)co1,,CN(C)C=O,,O,[H-].[Na+],test
US20120328569A1,CI.COC(=O)c1c(-c2ccc(F)cc2)oc2cc(NS(=O)(=O)c3ccccc3)c(Br)cc12>>COC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(=O)(=O)c3ccccc3)c(Br)cc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080103133A1,CC(C)(C)OC(=O)N[C@H]1CN(C(=O)OCC(F)(F)F)c2ccccc2N(CC(F)(F)F)C1=O.Cl>>Cl.N[C@H]1CN(C(=O)OCC(F)(F)F)c2ccccc2N(CC(F)(F)F)C1=O,,C1COCCO1,,,,test
US04145538,C=[N+]=[N-].NC(=O)OCC1=C(C(=O)O)N2C(=O)C(NC(=O)Cc3cccs3)[C@H]2SC1>>COC(=O)C1=C(COC(N)=O)CS[C@@H]2C(NC(=O)Cc3cccs3)C(=O)N12,,CCO,,,,test
US20110251247A1,CN(C)C=O.O=C([O-])NCc1cc(Br)ccc1F.[Li]CCCC>>CC(C)(C)OC(=O)NCc1cc(C=O)ccc1F,,C1CCOC1,,CCOC(C)=O,,test
US20160145247A1,CC(C)(C)OC(=O)Cc1ccccc1O.OCc1cc(Br)cc(CO)c1>>CC(C)(C)OC(=O)Cc1ccccc1OCc1cc(Br)cc(CO)c1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120142706A1,O=C1Cc2cccc(Cl)c2N1.O=[N+]([O-])O>>O=C1Cc2cc([N+](=O)[O-])cc(Cl)c2N1,,O=S(=O)(O)O,,,,test
US20130165472A1,CC(=O)Nc1cc(-c2cn(-c3ccc(Cl)cc3Cl)c(-c3ccnn3COCC[Si](C)(C)C)n2)c(C)cn1>>CC(=O)Nc1cc(-c2cn(-c3ccc(Cl)cc3Cl)c(-c3ccn[nH]3)n2)c(C)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160194329A1,CO.C[C@H]1CN(C(=O)Nc2ccc3c(c2)CCC3)CCN1c1nc(S(C)(=O)=O)nc2c1cnn2C>>COc1nc(N2CCN(C(=O)Nc3ccc4c(c3)CCC4)C[C@@H]2C)c2cnn(C)c2n1,,CO,,C[O-].[Na+],,test
US04766125,COc1ccc(C)cc1N.O=C(Cl)CCl>>COc1ccc(C)cc1NC(=O)CCl,,O,,Cc1ccccc1,,test
US04992433,COc1ccc(O)c(Cl)c1.ClCCCC1CCN(c2ccc(Cl)nn2)CC1>>COc1ccc(OCCCC2CCN(c3ccc(Cl)nn3)CC2)c(Cl)c1,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4nccs4)nc(Cl)c3n2)cc1.Nc1ccc2c(c1)NC(=O)CC2>>O=C1CCc2ccc(Nc3nc(-c4nccs4)nc4cn[nH]c34)cc2N1,C1COCCO1,CO,,Cl,,test
US06867200B1,N=C(N)c1ccc2[nH]c(-c3cccc(-c4nc5cnccc5[nH]4)c3O)nc2c1>>N=C(N)c1ccc2[nH]c(-c3cccc(-c4nc5c([nH]4)CNCC5)c3O)nc2c1,O=[Pt]=O,CO,,Cl,,test
US05166181,CN.O=C1CCCc2c(Br)cccc21.[BH3-]C#N>>CN(C)C1CCCc2c(Br)cccc21,,CCO,,CC(=O)O,,test
US20160039757A1,CC(C)(C(=O)OCc1ccccc1)c1cccc(Oc2cc([N+](=O)[O-])cc(C(F)(F)F)c2)c1>>CC(C)(C(=O)OCc1ccccc1)c1cccc(Oc2cc(N)cc(C(F)(F)F)c2)c1,[Fe],CCO,,O,[Cl-].[NH4+],test
US20050049245A1,CNC[C@@H](O)c1ccco1.O=C(NCc1ccc(Cl)cc1)c1cn(CCOCCOC2CCCCO2)c2sc(CCl)cc2c1=O>>CN(Cc1cc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(CCOCCOC3CCCCO3)c2s1)C[C@@H](O)c1ccco1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20010056117A1,COC(=O)C1CC(C#N)(c2ccc(OC)c3c2OCCO3)CCC1=O>>COc1ccc(C2(C#N)CCC(=O)CC2)c2c1OCCO2,,O,,CS(C)=O,[Cl-].[Na+],test
US20100204240A1,CC1(C)OC[C@@](C)(C=O)O1.NO>>CC1(C)OC[C@@](C)(C=NO)O1,,CO,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20150232469A1,CC(C)(C)OC(=O)N1CCNCC1.CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(S(C)(=O)=O)cc2Cl)CC1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US08304419B2,CC(C)(C)OC(=O)CC(=O)OC(C)(C)C.COc1cc(C#N)cc(Oc2c([N+](=O)[O-])ccc(F)c2F)c1>>COc1cc(C#N)cc(Oc2c([N+](=O)[O-])ccc(C(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c2F)c1,,C1CCOC1,,Cl,[H-].[Na+],test
US05240923,C=CCN1CC(O)c2ccsc2S1(=O)=O.C=COCC>>C=CCN1CC(OCCOCC)c2ccsc2S1(=O)=O,Cc1ccc(S(=O)(=O)O)cc1,C1CCOC1,CCOC(C)=O,,,test
US20090130076A1,CC(C)(C)OC(=O)Nc1nc2c(-c3cccc(Cl)c3)c(F)c(CBr)cc2s1.CCCC[Sn](CCCC)(CCCC)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)Nc1nc2c(-c3cccc(Cl)c3)c(F)c(Cc3ccc([N+](=O)[O-])cc3)cc2s1,,C1COCCO1,,,,test
US20060084679A1,CC(C)N1CCC(O)C1.CCOC(=O)c1ccc2cc(O)ccc2n1>>CCOC(=O)c1ccc2cc(OC3CCN(C(C)C)C3)ccc2n1,,C1CCOC1,Cc1ccccc1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20050215574A1,CN(C)C(=O)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>CN(C)C(=O)C1CC(OS(=O)(=O)c2ccc([N+](=O)[O-])cc2)CN1,,ClCCl,,c1ccncc1,,test
US20090018160A1,BrBr.C[Si](C)(C)c1onc(-c2cccnc2)c1[Si](C)(C)C>>C[Si](C)(C)c1onc(-c2cccnc2)c1Br,,ClC(Cl)(Cl)Cl,,,,test
US20050026973A1,CCOC(Cc1ccc(OCCn2c(=O)sc3cc(C(=O)c4ccccc4)ccc32)cc1)C(=O)OC.CON>>CCOC(Cc1ccc(OCCn2c(=O)sc3cc(C(=NOC)c4ccccc4)ccc32)cc1)C(=O)OC,,CO,,Cl,c1ccncc1,test
US05091407,COC(=O)Cn1cccc1C(=O)c1ccccc1.COC=O>>COC(=O)C(=CO)n1cccc1C(=O)c1ccccc1,,CN(C)C=O,,[H-].[Na+],O=C([O-])[O-].[K+].[K+],test
US20070135631A1,C[Si](C)(C)C=[N+]=[N-].O=C(NC(Cc1nn[nH]n1)(c1cccc(OC(F)(F)F)c1)c1cccc(OC(F)(F)F)c1)c1ccc(F)c(C(F)(F)F)c1>>Cn1nnc(CC(NC(=O)c2ccc(F)c(C(F)(F)F)c2)(c2cccc(OC(F)(F)F)c2)c2cccc(OC(F)(F)F)c2)n1,,C1CCOC1,CO,,,test
US20150361100A1,CC(C)[Si](OCC#Cc1c(N)ncnc1Cl)(C(C)C)C(C)C.CC(N)c1cc2ccccn2c1-c1ccccn1>>CC(Nc1ncnc(N)c1C#CCO[Si](C(C)C)(C(C)C)C(C)C)c1cc2ccccn2c1-c1ccccn1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20060094767A1,C[S+](C)(C)=O.O=C1CCN(c2ccc(C(F)(F)F)cc2)CC1>>FC(F)(F)c1ccc(N2CCC3(CC2)CO3)cc1,,CS(C)=O,,[H-].[Na+],,test
US20040127576A1,C=C(C)C(C)=O.COc1ccc2c(c1)CCC(=O)C2C>>COc1ccc2c(c1)CCC1=CC(=O)[C@@H](C)C[C@]12C,,Cc1ccccc1,,,,test
US20040162303A1,CN=C=O.COc1ccccc1C(=O)c1cnc(NC2CCNCC2)nc1N>>CNC(=O)N1CCC(Nc2ncc(C(=O)c3ccccc3OC)c(N)n2)CC1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US04452990,COc1ccc(C(=O)Cl)cc1.O=C1CCC(CCC(=O)OCc2ccccc2)N1>>COc1ccc(C(=O)N2C(=O)CCC2CCC(=O)OCc2ccccc2)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20150238601A1,CC(C)NC(=O)COc1cccc(B2OC(C)(C)C(C)(C)O2)c1.Nc1ccnc(Cl)n1>>CC(C)NC(=O)COc1cccc(-c2nccc(N)n2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,[Cs+].[F-],,test
US05521316,CCOC(=O)c1cccnc1.CCOC(=O)c1ccncc1>>OCc1cccnc1.OCc1ccncc1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04698352,CCOCC.COC(=O)CC(=O)C=CC1=CCCC1.Cc1cc(O)ccc1N>>COC(=O)C(=CNc1ccc(O)cc1C)C(=O)C=CC1=CCCC1,,c1ccccc1,,,,test
US20160002185A1,CCOC(=O)[C@H]1CCC(=O)N1[C@@H](c1cccc(Cl)c1)[C@H](NC(C)C)c1ccc(Cl)cc1>>CC(C)N[C@H](c1ccc(Cl)cc1)[C@H](c1cccc(Cl)c1)N1C(=O)CC[C@@H]1C(=O)O,,C1CCOC1,O,[Na+].[OH-],,test
US04672116,COc1cc(Cl)c2nc(Cl)nc(N)c2c1OC.NN>>COc1cc(Cl)c2nc(NN)nc(N)c2c1OC,,CO,,,,test
US20060293298A1,CC(C)N1CCC(Oc2ccc(C3CCNCC3)cc2)CC1.O=C(O)c1ccc(C(=O)N2CCC2)cc1>>CC(C)N1CCC(Oc2ccc(C3CCN(C(=O)c4ccc(C(=O)N5CCC5)cc4)CC3)cc2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20060211698A1,CN(C)c1ccc(B(O)O)cc1.COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccc(OS(=O)(=O)C(F)(F)F)cc3)n(CC(=O)N3CCOCC3)c2c1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccc(-c4ccc(N(C)C)cc4)cc3)n(CC(=O)N3CCOCC3)c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])O.[Na+],,test
US05773388,CC(=O)CC(=O)C(F)(F)Cl.CCOC([O-])[O-]>>CCOC=C(C(C)=O)C(=O)C(F)(F)Cl,,O,,CC(=O)OC(C)=O,,test
US20140275027A1,CC(C)(C)OC(=O)N1CC=C(c2cc3c(-c4cccc(F)c4F)ccnc3[nH]2)CC1>>Fc1cccc(-c2ccnc3[nH]c(C4=CCNCC4)cc23)c1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070298104A1,CCOC(=O)CN1C(=O)c2ccc([N+](=O)[O-])cc2C1=O.Cc1nc2ccc(O)cc2s1>>CCOC(=O)CN1C(=O)c2ccc(Oc3ccc4nc(C)sc4c3)cc2C1=O,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US04885386,CCC(C)(C)N.COC(=O)c1c(F)c(F)c(F)c(F)c1C(=O)OC>>CCC(C)(C)Nc1c(F)c(F)c(C(=O)OC)c(C(=O)OC)c1F,,O,,CS(C)=O,,test
US20130116245A1,C[C@H]1CN(C2COC2)[C@H](C)CN1c1ccc(Nc2cc(-c3cc(F)cc(-n4ccn5c6c(cc5c4=O)CCCC6)c3C=O)cn(C)c2=O)nc1>>C[C@H]1CN(C2COC2)[C@H](C)CN1c1ccc(Nc2cc(-c3cc(F)cc(-n4ccn5c6c(cc5c4=O)CCCC6)c3CO)cn(C)c2=O)nc1,,CO,,O,[BH4-].[Na+],test
US05891909,COc1ccc(OC)c(S(=O)(=O)Cl)c1.Cc1cc(O)cc(O)c1>>COc1ccc(OC)c(S(=O)(=O)Oc2cc(C)cc(O)c2)c1,,CCOCC,,O,O=C([O-])O.[Na+],test
US20110295017A1,Brc1ccc2c(-c3ccccc3)c3ccccc3c(-c3ccccc3)c2c1.CCOB(OCC)OCC>>OB(O)c1ccc2c(-c3ccccc3)c3ccccc3c(-c3ccccc3)c2c1,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US20090227594A1,CC(C)(C)OC(=O)NCCCCCCCCCCCC(=O)O.N>>CC(C)(C)OC(=O)NCCCCCCCCCCCC(N)=O,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US04717724,CCCCCCCC(=O)N1CCc2cc(OC)ccc2C1>>CCCCCCCCN1CCc2cc(OC)ccc2C1,,CCOCC,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20070276138A1,CC1(C)OC(=O)[C@H](Cc2ccc(OCc3ccccc3)cc2)O1>>CC1(C)OC(=O)[C@H](Cc2ccc(O)cc2)O1,[Pd],CCOC(C)=O,,,,test
US20090253699A1,CCOC(=O)c1cccc(-c2nc(-c3ccc(C(C)C)cc3)cs2)c1>>CC(C)c1ccc(-c2csc(-c3cccc(C(=O)O)c3)n2)cc1,,CO,O,[Li+].[OH-],,test
US20060252943A1,COS(=O)(=O)OC.Cc1n[nH]c2cc([N+](=O)[O-])ccc12>>Cc1c2ccc([N+](=O)[O-])cc2nn1C,,CS(C)=O,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US20150232445A1,COC(=O)N1c2ccc(-c3cn[nH]c3)c(OC3CCC3)c2CC[C@@H]1C.CS(=O)(=O)OC1CCS(=O)(=O)CC1>>COC(=O)N1c2ccc(-c3cnn(C4CCS(=O)(=O)CC4)c3)c(OC3CCC3)c2CC[C@@H]1C,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070179115A1,CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@H](n2c(NCc3ccc(-c4cccc(OCc5ccccc5)c4)cc3)nc3c(N)ncnc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C>>CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@H](n2c(NCc3ccc(-c4cccc(O)c4)cc3)nc3c(N)ncnc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C,[Pd],CCOC(C)=O,,,,test
US20160096834A1,CC(C)(C)c1ccc(C(=O)Cl)cc1.COc1ccc(-c2nc3c(-c4ccc(CN)c(F)c4)ccnc3[nH]2)cc1>>COc1ccc(-c2nc3c(-c4ccc(CNC(=O)c5ccc(C(C)(C)C)cc5)c(F)c4)ccnc3[nH]2)cc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20030045552A1,Nc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=C(Cl)c1ccc(F)cc1>>O=C1CCC(N2C(=O)c3cccc(NC(=O)c4ccc(F)cc4)c3C2=O)C(=O)N1,,C1CCOC1,,CO,,test
US20060142265A1,C=CC(=O)Cl.CCCOc1c(CCN)cccc1C(C)C>>C=CC(=O)N(C)Cc1cccc(C(C)C)c1OCCC,,ClCCl,,CCN(CC)CC,,test
US20080027067A1,O=C1[C@@H](N2CCc3ccccc32)CCN1c1ccc(S(=O)(=O)Nc2nccs2)cc1>>O=C1[C@@H](n2ccc3ccccc32)CCN1c1ccc(S(=O)(=O)Nc2nccs2)cc1,O=[Mn]=O,ClCCl,,,,test
US20130252941A1,[N-]=[N+]=Nc1c(F)cncc1/C=N/c1c(Cl)cc(Br)cc1Cl>>Fc1cncc2cn(-c3c(Cl)cc(Br)cc3Cl)nc12,,Cc1ccccc1,,,,test
US05206257,FC(F)(F)c1cc(Cl)c(-c2nc(Br)c[nH]2)c(Cl)c1.O=[N+]([O-])O>>O=[N+]([O-])c1[nH]c(-c2c(Cl)cc(C(F)(F)F)cc2Cl)nc1Br,,O,,O=S(=O)(O)O,,test
US04725610,BrBr.CC(=O)c1nc(-c2ccccc2)oc1C>>Cc1oc(-c2ccccc2)nc1C(=O)CBr,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20090181928A1,NC(=O)c1cccc(C=Cc2ccc(N3CC(=O)NS3(=O)=O)c(OCc3ccccc3)c2)c1>>NC(=O)c1cccc(CCc2ccc(N3CC(=O)NS3(=O)=O)c(O)c2)c1,[Pd],CCO,O,,,test
US20150018343A1,CC(=O)CC(C)=O.CC(C)(C)OC(=O)N1Cc2n[nH]c(N)c2C1>>Cc1cc(C)n2nc3c(c2n1)CN(C(=O)OC(C)(C)C)C3,,CC(=O)O,,O=C([O-])O.[Na+],,test
US20090176786A1,CNC(=O)N(C)c1ccc(SC(F)(F)F)cc1F.O=C(Cl)c1c(F)cccc1F>>CN(C(=O)c1c(F)cccc1F)C(=O)N(C)c1ccc(SC(F)(F)F)cc1F,,c1ccncc1,,CCOC(C)=O,O,test
US20090275570A1,C[C@H]1[C@@H](NC(=O)OC(C)(C)C)CCCN1C(=O)OCc1ccccc1>>C[C@H]1[C@@H](N)CCCN1C(=O)OCc1ccccc1,,CO,,Cl,,test
US20090156516A1,CCc1ccc(Cc2cc(Cl)ccc2O)cc1.O[C@H]1C=C(COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>CCc1ccc(Cc2cc(Cl)ccc2O[C@@H]2C=C(COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080153810A1,CN(C)CCN(C)c1n[nH]c2ccc([N+](=O)[O-])cc12>>CN(C)CCN(C)c1n[nH]c2ccc(N)cc12,[Pd],CO,,,,test
US20130096144A1,CC(C)(C)OC(=O)NC[C@H](c1ccccc1)N1Cc2cc(Br)ccc2C1=O.Cn1ncc(Cl)c1B1OC(C)(C)C(C)(C)O1>>Cn1ncc(Cl)c1-c1ccc2c(c1)CN([C@@H](CN)c1ccccc1)C2=O,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,C1COCCO1,O,CCN(C(C)C)C(C)C,,test
US04661477,CCCCOCCCN.COP([O-])OC>>CCCCOCCC[NH3+].COP=O,,CO,,O,,test
US20100298324A1,COC(=O)c1cc(N)c(C(=O)OC)c(Cl)c1.S=C(Cl)Cl>>COC(=O)c1cc(Cl)c(C(=O)OC)c(N=C=S)c1,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20090275578A1,COC(=O)c1c(Cl)cc(Br)cc1CBr.NCc1ccc(Cl)cc1>>O=C1c2c(Cl)cc(Br)cc2CN1Cc1ccc(Cl)cc1,,CCCCCC,Cc1ccccc1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20050267105A1,CCOC(=O)c1nc(C(CCSC)OCCO)[nH]c(=O)c1OCc1ccccc1>>CCOC(=O)c1nc2n(c(=O)c1OCc1ccccc1)CCOC2CCSC,,CCOCC,ClCCl,CCN(CC)CC,CS(=O)(=O)Cl,test
US06114325,CCCCCCCCCCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCCN(CCO)CCO.Cl>>CCCCCCCCCCCCCCCCCCN(C=O)c1ccccc1COC(=O)NCCCN(CCO)CCO.Cl,,CCOC(C)=O,ClC(Cl)Cl,,,test
US05057516,CCOC(=O)Nc1cc2nc(O)c(O)nc2cc1Cl.O=[N+]([O-])O>>CCOC(=O)Nc1c(Cl)cc2nc(O)c(O)nc2c1[N+](=O)[O-],,CC(=O)O,,,,test
US20100256092A1,COC(=O)c1ccc(Oc2nncs2)cc1B1OC(C)(C)C(C)(C)O1>>OB1OCc2ccc(Oc3nncs3)cc21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04033947,CCO.CN(CCN1NC2=CC(=O)N(c3ccccc3)c3cc(Cl)ccc3N2C1=O)Cc1ccccc1>>CNC(C)CN1NC2=CC(=O)N(c3ccccc3)c3cc(Cl)ccc3N2C1=O,[Pd],,,,,test
US20040229858A1,CC(C)(C)OC(=O)N1CCCC1C=C(Br)Br>>C#CC1CCCN1C(=O)OC(C)(C)C,,C1CCOC1,,[Li]CCCC,,test
US20140221311A1,CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ncccc2-c2ccc(-c3cnc(N)cn3)c(F)c2)C1.Cl>>Cl.Nc1cnc(-c2ccc(-c3cccnc3S(=O)(=O)C3CCNC3)cc2F)cn1,,ClCCl,,CCO,,test
US20100316601A1,CC1=NN(c2ccc3c(c2)CCC3)C(=O)C1.Nc1cc(F)cc(-c2cccc(C(=O)O)c2)c1O.O=N[O-]>>CC1=NN(c2ccc3c(c2)CCC3)C(=O)C1=NNc1cc(F)cc(-c2cccc(C(=O)O)c2)c1O,,CCO,Cl,O=C([O-])O.[Na+],,test
US06417009B1,CNC(=O)CC(C)CCCC(C)CCCC(C)CCCC(C)C>>CNCCC(C)CCCC(C)CCCC(C)CCCC(C)C,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120219522A1,C1CO1.COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(C)n(-c5ccccc5)c4=O)cc3)ccnc2cc1O>>COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(C)n(-c5ccccc5)c4=O)cc3)ccnc2cc1OCCO,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130211075A1,CCOC(=O)C(C)(C)Br.Cc1c(C(=O)Nc2ccc(C3(C#N)CCNCC3)nc2)cnn1-c1ccc(C(F)(F)F)cn1>>CCOC(=O)C(C)(C)N1CCC(C#N)(c2ccc(NC(=O)c3cnn(-c4ccc(C(F)(F)F)cn4)c3C)cn2)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090054392A1,C1CCOC1.NN.O=C1C=C(c2ccc3ccccc3c2)C(=O)O1.O=c1cc(-c2ccc3ccccc3c2)c(=O)[nH][nH]1>>NCC1CCN(c2cc(-c3ccc4ccccc4c3)cnn2)CC1,,O,,Cl,Cl,test
US05679696,COc1ccc(C(=O)Cc2c(Cl)cncc2Cl)cc1OC1CCCC1.OO>>COc1ccc(C(=O)Cc2c(Cl)c[n+]([O-])cc2Cl)cc1OC1CCCC1,,CC(=O)O,CCOC(C)=O,,,test
US20040127536A1,Nc1ccc(-c2nn(C3CCCCO3)c3ccc(-c4ncn(C(c5ccccc5)(c5ccccc5)c5ccccc5)n4)cc23)cc1.O=C(Cl)c1ccco1>>O=C(Nc1ccc(-c2n[nH]c3ccc(-c4ncn[nH]4)cc23)cc1)c1ccco1,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20150376208A1,Cc1ccc(O)cc1[N+](=O)[O-].O=[N+]([O-])O>>Cc1ccc(O)c([N+](=O)[O-])c1[N+](=O)[O-],,CC(=O)O,O,,,test
US20090098218A1,N#Cc1ccc(OCCN2CCOCC2)cc1.[Li]N([Si](C)(C)C)[Si](C)(C)C>>N=C(N)c1ccc(OCCN2CCOCC2)cc1,,C1CCOC1,,Cl,,test
US20100197725A1,CCOCCN.CS(=O)(=O)OCCc1ccccc1Br>>CCOCCNCCc1ccccc1Br,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20160176864A1,CS(=O)(=O)c1ccc2c(c1)[nH]c1cc(Br)cnc12.O[C@@H](c1ccccc1)C1CCOCC1>>CS(=O)(=O)c1ccc2c3ncc(Br)cc3n([C@H](c3ccccc3)C3CCOCC3)c2c1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05962002,CCOC(=O)C=C1CCCCC1>>OCC=C1CCCCC1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120010188A1,COC(=O)c1ccc(N)nc1.O=C(CBr)c1ccc(Cl)cc1>>Br.COC(=O)c1ccc2nc(-c3ccc(Cl)cc3)cn2c1,,CCO,,,,test
US04544747,C1CNCCN1.CCn1cc(C(=O)O)c(=O)c2ccc(Cl)c(C)c21>>CCn1cc(C(=O)O)c(=O)c2ccc(N3CCNCC3)c(C)c21.Cl,,CN(C)P(=O)(N(C)C)N(C)C,,,,test
US20100204472A1,CCCN(CCCOc1ccc2c(c1)CC[C@H]2CC(=O)OCC)c1ccc(-c2nc(C)c(C)s2)cn1>>CCCN(CCCOc1ccc2c(c1)CC[C@H]2CC(=O)O)c1ccc(-c2nc(C)c(C)s2)cn1,,C1CCOC1,,CO,O,test
US20070104644A1,COC(=O)CCN(C1(C(=O)OCc2ccccc2)CCCC1)S(=O)(=O)c1ccc(-c2ccc(F)cc2)cc1>>COC(=O)CCN(C1(C(=O)O)CCCC1)S(=O)(=O)c1ccc(-c2ccc(F)cc2)cc1,[Pd],CO,,,,test
US20020183336A1,CC(=O)c1ccc2c(c1O)O[C@@H](CO)CO2.NO>>CC(=NO)c1ccc2c(c1O)OC(CO)CO2,,CCO,,Cl,c1ccncc1,test
US03962443,CCO.CCOC(=O)c1cnc2nc(N3CCN(C)CC3)ncc2c1Cl>>CCOC(=O)c1cnc2nc(N3CCN(C)CC3)ncc2c1OCC,,CCO,,C,C[O-].[Na+],test
US20020183320A1,Nc1nccs1.O=Cc1cccc(Cl)c1Cl.[C-]#[N+]C(C)(C)C>>CC(C)(C)Nc1c(-c2cccc(Cl)c2Cl)nc2sccn12,,[O-][Cl+3]([O-])([O-])O,,,,test
US20140323418A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(=O)c1cnc(N[C@@H]2CCC[C@H](O)[C@@H]2N)nc1Nc1cccc(-n2nccn2)c1>>CC(C)(C)OC(=O)N[C@@H]1[C@H](Nc2ncc(C(N)=O)c(Nc3cccc(-n4nccn4)c3)n2)CCC[C@@H]1O,,CCO,,CCN(CC)CC,,test
US20070259965A1,CC(CCNC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1>>CC(N)CCNC(=O)OC(C)(C)C,[Pd],CCO,,,,test
US20150225449A1,COc1ccc(-c2ccccc2)cc1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)[C@H](C)N(C(C)=O)c2cc(C#N)ccc21.Cl>>CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cc(-c3ccccc3)ccc2OC)c2ccc(C#N)cc2N(C(C)=O)[C@H]1C.Cl,,C1COCCO1,CCOCC,,,test
US20120114739A1,CC(C)(C)OC(=O)N1CCC(CO)CC1.C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)c1cc(Cl)nc2c(-c3cnc4ccccc4c3)cnn12.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N1CCC(COc2nc3c(-c4cnc5ccccc5c4)cnn3c(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)c2Br)CC1,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20110178089A1,COC(=O)CNC(=O)c1cc(Cl)c(Oc2ccncc2C(=O)N2CCN(C3CC3)c3ccccc32)cc1Cl.NCCS(=O)(=O)O>>O=C(NCCS(=O)(=O)O)c1cc(Cl)c(Oc2ccncc2C(=O)N2CCN(C3CC3)c3ccccc32)cc1Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140194469A1,CCCCC(C)=O.COC(OC)N(C)C>>CCCCC(=O)/C=C/N(C)C,,CN(C)C=O,,,,test
US20120220586A1,FC(F)(F)c1ccccc1-c1nc2c(Cl)cccc2nc1CNc1ncnc2[nH]cnc12.OB(O)c1cc(F)ccc1Cl>>Cc1nc2cccc(Cl)c2nc1-c1cc(F)ccc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,O,O=C(O)O,,test
US20130295141A1,O=CO[C@H](CCc1ccc(-c2cc(F)cc(F)c2)cc1)[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)O>>O=C(O)[C@@H](CCN1C(=O)c2ccccc2C1=O)[C@H](O)CCc1ccc(-c2cc(F)cc(F)c2)cc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20140011795A1,CCSc1c(C(N)=O)cnn2cc(-c3nnn[nH]3)cc12.CI>>CCSc1c(C(N)=O)cnn2cc(-c3nnn(C)n3)cc12,,CN1CCCC1=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20080015193A1,Cc1nc2ccc(C(=O)NCC(=O)c3ccccc3)cc2[nH]1>>Cc1nc2ccc(-c3ncc(-c4ccccc4)o3)cc2[nH]1,,O=P(Cl)(Cl)Cl,,,,test
US04843066,CC#N.N#Cc1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1N>>Cc1nc(N)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1,,CO,N,,,test
US20160152605A1,COc1ccncc1.Fc1ccc([Mg]Br)cc1.O=C(Cl)Oc1ccccc1>>O=C1C=CN(C(=O)Oc2ccccc2)C(c2ccc(F)cc2)C1,,C1CCOC1,,,,test
US04000260,Cc1ccc(S(=O)(=O)Cl)cc1.O=c1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1>>Cc1ccc(S(=O)(=O)OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)C[C@@H]2O)cc1,,c1ccncc1,,,,test
US20110144090A1,C1COCCN1.CCn1cc(CC(=O)O)c2c(O)cc(F)cc21>>CCn1cc(CC(=O)N2CCOCC2)c2c(O)cc(F)cc21,,CN(C)C=O,O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20030149062A1,C[C@H](O)CN(CC=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCC1CC1)CC(=O)OC(C)(C)C>>C[C@H]1CN(CC=CC(=O)Nc2cc3c(Nc4ccc(F)c(Cl)c4)ncnc3cc2OCC2CC2)CC(=O)O1,,CC#N,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20090176786A1,CN(C(=O)NC(=O)c1c(F)cccc1F)c1ccc(S(=O)C(F)(F)F)cc1F.O=C(OO)c1cccc(Cl)c1>>CN(C(=O)NC(=O)c1c(F)cccc1F)c1ccc(S(=O)(=O)C(F)(F)F)cc1F,,ClC(Cl)Cl,,,,test
US06800637B2,CS(C)=O.N#Cc1ccc2[nH]cc(CCCN)c2c1.O=S(=O)(OC[C@H]1COc2ccc3ncccc3c2O1)c1ccc(Br)cc1>>Cc1ccc2c3c(ccc2n1)OCC(CNCCCc1c[nH]c2ccc(C#N)cc12)O3,,CS(C)=O,,CCN(CC)CC,,test
US08314103B2,NC(=NO)c1ccc(NC(=O)CCl)cn1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(CCl)Nc1ccc(-c2noc(C(F)(F)F)n2)nc1,,O,,N,,test
US20160009703A1,C1CCC(=C2CCNCC2)CC1.ClCCCCn1nnc2ccccc21>>c1ccc2c(c1)nnn2CCCCN1CCC(C2CCCCC2)CC1,,CC#N,,CCN(C(C)C)C(C)C,[I-].[K+],test
US20050107377A1,BrCCCOc1ccc(-c2csc3ccccc23)cc1.NCc1ccccc1F>>Fc1ccccc1CNCCCOc1ccc(-c2csc3ccccc23)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05364871,CC(=O)NCc1cccc(-c2csc(N)n2)n1.CN=C=S>>CNC(=S)Nc1nc(-c2cccc(CNC(C)=O)n2)cs1,,CCO,,CCOC(C)=O,,test
US20100298347A1,CC(C)(C)OC(=O)N1CCC(c2ccc(-c3cc(C(=O)O)cc4cc(-c5ccc(C(F)(F)F)cc5)ccc34)cc2)CC1.CS(=O)(=O)O>>CS(=O)(=O)[O-].O=C(O)c1cc(-c2ccc(C3CC[NH2+]CC3)cc2)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140221345A1,CCOC(=O)C(C)(C)Oc1cccc2cccnc12.NCC(O)CN1CCc2ccccc2C1>>CC(C)(Oc1cccc2cccnc12)C(=O)NCC(O)CN1CCc2ccccc2C1,,CCO,,,,test
US20040204462A1,Cc1oc(-c2ccc3ccccc3c2)[n+]([O-])c1C.O=P(Cl)(Cl)Cl>>Cc1oc(-c2ccc3ccccc3c2)nc1CCl,,ClC(Cl)Cl,,N,,test
US20140128372A1,Fc1cccc(F)c1CBr.Nc1nccc(F)c1O>>Nc1nccc(F)c1OCc1c(F)cccc1F,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130150339A1,Cc1cc2c(O)ccnc2cc1Br.O=P(Cl)(Cl)Cl>>Cc1cc2c(Cl)ccnc2cc1Br,,CC#N,,,,test
US20050182066A1,CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12.O=C(O)CC(O)(CC(=O)O)C(=O)O>>CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12.O=C(O)CC(O)(CC(=O)O)C(=O)O,,CC(C)=O,,,,test
US04639451,CC1CC(=O)NN=C1c1ccc(N)cc1.O=C(Cl)c1cccs1>>CC1CC(=O)NN=C1c1ccc(NC(=O)c2cccs2)cc1,,c1ccccc1,,,,test
US20140179667A1,COc1ccc(CNCCO)cc1.Cc1c(Br)ccc(F)c1C(=O)O>>COc1ccc(CN(CCO)C(=O)c2c(F)ccc(Br)c2C)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05623081,C1COC2(CCSCC2)O1.OO>>O=S1CCC2(CC1)OCCO2,,CC(=O)O,,,,test
US20120142694A1,COc1ccc(-c2ccc(C(C)(C)NC(C)=O)cn2)cc1.O=S(=O)(O)c1ccccc1>>COc1ccc(-c2ccc(C(C)(C)N)cn2)cc1.O=S(=O)(O)c1ccccc1,,O,,Cl,[Na+].[OH-],test
US20140018335A1,CON(C)C(=O)c1ccccc1.Cc1cc(C2CC2)ccc1NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)Nc1ccc(C2CC2)cc1CC(=O)c1ccccc1,,C1CCOC1,,[Li]C(C)CC,,test
US05886011,CC1(C)Cc2cccc(C=O)c2O1.Nc1cccnc1Cl>>CC1(C)Cc2cccc(CNc3cccnc3Cl)c2O1,,CC(=O)O,,,,test
US20020013328A1,CC(C)c1[nH]n(-c2c(Cl)cc(Cl)cc2Cl)c2nc(Cc3ccc(N(C(=O)OC(C)(C)C)C(=O)[C@@H]4CCCN4)cc3)nc(=O)c1-2>>CC(C)c1[nH]n(-c2c(Cl)cc(Cl)cc2Cl)c2nc(Cc3ccc(NC(=O)[C@@H]4CCCN4)cc3)nc(=O)c1-2,,Cl,,,,test
US05998433,CN(C)Cc1cc2c(o1)CCN(C(=O)c1ccc(C(=O)c3cccc(Cl)c3)cc1)C2.Cl>>CN(C)Cc1cc2c(o1)CCN(C(=O)c1ccc(C(=O)c3cccc(Cl)c3)cc1)C2.Cl,,CCOC(C)=O,CO,,,test
US05952382,BrCc1ccccc1.Oc1cc2ccc(Br)cc2cc1C12CC3CC(CC(C3)C1)C2>>Brc1ccc2cc(OCc3ccccc3)c(C34CC5CC(CC(C5)C3)C4)cc2c1,,CCO,CN(C)C=O,O,[H-].[Na+],test
US20150087663A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)O.Nc1cccc(F)c1C(=O)Nc1ccccc1>>C[C@H](NC(=O)OC(C)(C)C)C(=O)Nc1cccc(F)c1C(=O)Nc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090098218A1,BrBr.COc1ccc(-c2ncc3c(n2)C(=O)CCC3)cc1>>COc1ccc(-c2ncc3c(n2)C(=O)C(Br)CC3)cc1,,Br,,,,test
US20150025093A1,Clc1ncnc2scc(-c3ccccn3)c12.NC1CCC(N)CC1>>NC1CCC(Nc2ncnc3scc(-c4ccccn4)c23)CC1,,CN(C)C=O,,,,test
US20160039841A1,COC(=O)CCn1c(=O)c2c(C)c(-c3ccc(Cl)cc3)sc2n(C)c1=O>>Cc1c(-c2ccc(Cl)cc2)sc2c1c(=O)n(CCCO)c(=O)n2C,,CCO,,[BH4-].[Na+],,test
US20140315888A1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2c1nc2ncc(Cl)cc2nc1Cl.CCOCC.NN>>CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2c1nc2ncc(Cl)cc2n2cnnc12,,CCOCC,,CCO,O,test
US20110301143A1,CC(C)(C)OC(=O)N1CCNCC1.N#Cc1nnc(Br)s1>>CC(C)(C)OC(=O)N1CCN(c2nnc(C#N)s2)CC1,,C1COCCO1,,CCN(C(C)C)C(C)C,[Cl-].[NH4+],test
US04863920,C#Cc1ncn2c1CN(C)C(=O)c1c(Cl)cccc1-2.CI>>CC#Cc1ncn2c1CN(C)C(=O)c1c(Cl)cccc1-2,,CCCCCC,CN(C)C=O,O,[H-].[Na+],test
US20150025087A1,COc1ncnc(Cn2cc(N)c3ncccc32)c1C.O=C(O)CC1CC1>>COc1ncnc(Cn2cc(NC(=O)CC3CC3)c3ncccc32)c1C,,ClCCl,O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US03989522,CCn1c(C)nc2cc(C(N)=O)ccc21>>CCn1c(C)nc2cc(C#N)ccc21,,c1ccncc1,,O=P(Cl)(Cl)Cl,,test
US20090298807A1,CC(C)(C)[Si](C)(C)Cl.OCCCc1ccccc1F>>CC(C)(C)[Si](C)(C)OCCCc1ccccc1F,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US05763700,COC(=O)C(F)=CC1(c2ccc3c(c2)OCO3)CC1>>OCC(F)=CC1(c2ccc3c(c2)OCO3)CC1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04205071,CN(C)C(N)=S.CN(C)CCCO>>CN(C)CCCSC(=N)N(C)C,,Br,,,,test
US20150119380A1,Cc1cnc(N)c(C)n1.O=C(CBr)c1cc2ccc(Br)cc2oc1=O>>Cc1cn2cc(-c3cc4ccc(Br)cc4oc3=O)nc2c(C)n1,,CC#N,,O=C([O-])O.[Na+],,test
US20150315188A1,CC1(c2cncc(F)c2)CO1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>Cc1ccc2c(c1)c1c(n2C[C@@](C)(O)c2cncc(F)c2)CCN(C)C1,,CN(C)C=O,,[H-].[Na+],,test
US06391520B1,C=C(C)C(=O)Cl.OC12CC3CC(O)(C1)CC(O)(C3)C2>>C=C(C)C(=O)OC12CC3CC(O)(CC(O)(C3)C1)C2,,O,,C1CCOC1,CCN(CC)CC,test
US20060264493A1,CC1CCc2c([nH]c3ccc(C(=O)O)cc23)C1=O.CO>>COC(=O)c1ccc2[nH]c3c(c2c1)CCCC3=O,,CO,O,O=C([O-])O.[Na+],,test
US20080207645A1,CC1(C)Cc2c(c(N3CCCC3)nc3sc4c(Cl)ncnc4c23)CO1.NCc1ccncc1>>CC1(C)Cc2c(c(N3CCCC3)nc3sc4c(NCc5ccncc5)ncnc4c23)CO1,,CCO,,,,test
US20100113391A1,CCOC(=O)CNCCn1c(=O)c2cc(F)c(NC3CCCCC3)cc2n(C2CCCC2)c1=O.CI>>CCOC(=O)CN(C)CCn1c(=O)c2cc(F)c(NC3CCCCC3)cc2n(C2CCCC2)c1=O,,O,,C1CCOC1,O=C([O-])[O-].[K+].[K+],test
US20160016948A1,CCOC(C)/C=N/c1cnc(Br)cc1NC(C)C(F)(F)F>>Cc1nc2cnc(Br)cc2n1C(C)C(F)(F)F,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20120083502A1,C[Mg]Br.O=Cc1nc2ccc(F)cn2c(=O)c1Br>>CC(O)c1nc2ccc(F)cn2c(=O)c1Br,,C1CCOC1,,CCOCC,,test
US20040063732A1,Clc1nc(Cl)c2[nH]cnc2n1.Nc1ccc(Cl)cc1>>Clc1ccc(Nc2nc(Cl)nc3[nH]cnc23)cc1,,CCCCO,,,,test
US20040044235A1,BrBr.C[SiH](C)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>C[Si](C)(Br)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F,,ClC(Cl)(Cl)Cl,,,,test
US20020028823A1,CCOCn1c(S)nc2c1c(=O)n(CCCC[C@@H](C)O)c(=O)n2C.CI>>CCOCn1c(SC)nc2c1c(=O)n(CCCC[C@@H](C)O)c(=O)n2C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05464865,COC(=O)c1ccc(CCl)cc1.Oc1ccc2ccccc2c1>>COC(=O)c1ccc(COc2ccc3ccccc3c2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04839365,Brc1cccs1.CC(=O)Cl>>CC(=O)c1ccc(Br)s1,,ClCCl,,Cl,,test
US20110319380A1,CCOC(=O)C=CC1CCCN1C(=O)OC(C)(C)C>>CCOC(=O)CCC1CCCN1C(=O)OC(C)(C)C,[Pd],CO,,[H][H],,test
US05668161,CSc1ccccc1.O=C(Cl)Cc1ccc(F)cc1>>CSc1ccc(C(=O)Cc2ccc(F)cc2)cc1,,S=C=S,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20060019997A1,CC(O)c1nn(-c2cccc(Cl)c2)c(=O)[nH]1.O=S(Cl)Cl>>CC(Cl)c1nc(=O)n(-c2cccc(Cl)c2)[nH]1,,ClCCl,,,,test
US04957935,CC(C(Cl)=NNc1c(Cl)cc(C(F)(F)F)cc1Cl)C(F)(F)F.CCCNC#N>>CCCNc1nc(C(C)C(F)(F)F)nn1-c1c(Cl)cc(C(F)(F)F)cc1Cl,,C1CCOC1,,CCN(CC)CC,,test
US20130096113A1,Clc1nccnc1Cl.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cn1cc(-c2nccnc2Cl)cn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20060235031A1,C=C1CC(C(=O)O)C1.NC(c1ccc2ccc(-c3ccccc3)nc2c1)c1nccnc1Cl>>C=C1CC(C(=O)NC(c2ccc3ccc(-c4ccccc4)nc3c2)c2nccnc2Cl)C1,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20100069367A1,N#CCC(=O)C(F)(F)F.NNc1ccccc1C(F)(F)F>>Nc1cc(C(F)(F)F)nn1-c1ccccc1C(F)(F)F,,Cc1ccccc1,,,,test
US04078071,ClC(CCc1ccccc1)Cn1ccnc1.SCc1ccc(Cl)c(Cl)c1>>Clc1ccc(CSC(CCc2ccccc2)Cn2ccnc2)cc1Cl,,C1CCOC1,,Cl,[H-].[Na+],test
US20130324579A1,O=[N+]([O-])c1cnn(CCN2CCc3ccccc32)c1>>Nc1cnn(CCN2CCc3ccccc32)c1,O=[Pt]=O,CCO,CCOC(C)=O,,,test
US05364871,CCCCN.CSC(N)=Nc1nc(-c2cccc(CNC(C)=O)n2)cs1>>CCCCNC(N)=Nc1nc(-c2cccc(CNC(C)=O)n2)cs1,,CCO,,I,,test
US05273982,N=C(NC(=O)OCc1ccccc1)c1ccc(C(=O)N2CCC[C@H]2CC(=O)NCCC(=O)O)cc1>>N=C(N)c1ccc(C(=O)N2CCC[C@H]2CC(=O)NCCC(=O)O)cc1,[Pd],CC(=O)O,,,,test
US20100136142A1,CC1=C(C(=O)OCCC#N)C(c2ccc(Br)cc2OC(F)(F)F)c2c(cc[nH]c2=O)N1.CCOC(OCC)OCC>>CCOc1nccc2c1C(c1ccc(Br)cc1OC(F)(F)F)C(C(=O)OCCC#N)=C(C)N2,O=S(=O)(O)O,,,,,test
US20090005356A1,BrC(Br)(Br)Br.CC(C)[Si](C(C)C)(C(C)C)n1ccc2c(C(F)(F)F)ccnc21>>FC(F)(F)c1c(Br)cnc2[nH]ccc12,,C1CCOC1,,[Li]C(C)CC,,test
US20160264552A1,CC(C)(C)OC(=O)Nc1ccc(C(=O)N2CCC(Nc3ncc(Cl)c(-c4cn(S(=O)(=O)c5ccccc5)c5ccccc45)n3)CC2)cc1.O=C(O)C(F)(F)F>>Nc1ccc(C(=O)N2CCC(Nc3ncc(Cl)c(-c4cn(S(=O)(=O)c5ccccc5)c5ccccc45)n3)CC2)cc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20150018373A1,CCn1nc2ccc(Br)cc2c1C.O=c1cc(OCc2ccc(Cl)cc2)cc[nH]1>>CCn1nc2ccc(-n3ccc(OCc4ccc(Cl)cc4)cc3=O)cc2c1C,[Cu]I,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=C([O-])[O-].[K+].[K+],test
US20120214855A1,Cn1ncc(C(=O)O)c1Br.N#Cc1c(Oc2cc(N)c(F)cc2Cl)ccc2nc(NC(=O)C3CC3)sc12>>Cn1ncc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)sc4c3C#N)c(Cl)cc2F)c1Br,,C1CCOC1,CCOC(C)=O,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20060111406A1,CCOC(=O)[C@H](Cc1ccc(OCC(=O)OC(C)(C)C)cc1)OC>>CCOC(=O)[C@H](Cc1ccc(OCC(=O)O)cc1)OC,,ClCCl,,O=C(O)C(F)(F)F,,test
US04287341,COc1cc2nc(Cl)nc(N)c2cc1Cl.O=C(c1ccco1)N1CCNCC1>>COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)nc(N)c2cc1Cl.Cl,,CC(C)CCO,,,,test
US20060199829A1,COc1cc2c(cc1OC)CN(c1ccc(C(=O)[O-])cn1)CC2.NO>>COc1cc2c(cc1OC)CN(c1ccc(C(=O)NO)cn1)CC2,,C1COCCO1,,[Na+].[OH-],,test
US20040053908A1,COC(=O)c1cc2c(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)ccnc2cc1OC>>COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(=O)O,,CO,,Cl,[Na+].[OH-],test
US20090264428A1,CC(=O)OC(C)=O.CCc1cccc(-c2c(Cl)cccc2[C@](O)(CCCN)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1>>CCc1cccc(-c2c(Cl)cccc2[C@](O)(CCCNC(C)=O)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1,,ClCCl,,CCN(CC)CC,,test
US03959292,CCOC(=O)C=C(N)N1CCCC1.CCOC(=O)CC(=O)C=Cc1cccc2ccccc12>>CCOC(=O)C1=C(N2CCCC2)N=C(C)C(C(=O)OCC)C1c1cccc2ccccc12,,CCO,,,,test
US20090111798A1,CCOC(=O)C1CCCC1=O.NCc1ccc(F)cc1>>CCOC(=O)C1=C(NCc2ccc(F)cc2)CCC1,,Cc1ccccc1,,CC(=O)O,,test
US20120225867A1,CC(=O)CCn1cnc(C(=O)N[C@@H](C)Cn2ccc(-c3ccc(C#N)c(Cl)c3)n2)c1.C[Mg]Br>>C[C@@H](Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1cn(CCC(C)(C)O)cn1,,C1CCOC1,CCOCC,[Cl-].[NH4+],,test
US06100419,C=C(C)OC(C)=O.CC(C)(O)C#N.ON=C1CCCCC1>>CC(=O)ONC1(C#N)CCCCC1,,Cc1ccccc1,,,,test
US05985306,COc1ccc2c(c1)OC[C@@H](c1ccccc1)[C@H]2c1ccc(O)cc1.ClCCN1CCCC1>>COc1ccc2c(c1)OC[C@@H](c1ccccc1)[C@H]2c1ccc(OCCN2CCCC2)cc1,,Cc1ccccc1,O,Cl,[Na+].[OH-],test
US20030176460A1,CC(C)(C)OC(=O)N[C@@H](C=O)Cc1ccccc1.O=C(c1ccc(F)cc1)C1CCNCC1>>CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)CN1CCC(C(=O)c2ccc(F)cc2)CC1,,C1CCOC1,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100105642A1,CC(C)(C)OC(=O)CCOCCc1cccc(C#C[Si](C)(C)C)c1>>C#Cc1cccc(CCOCCC(=O)OC(C)(C)C)c1,,ClCCl,O,CO,O=C([O-])[O-].[K+].[K+],test
US20120059002A1,C=C[Sn](CCCC)(CCCC)CCCC.Cc1cc(-c2nc3ccc(Br)cc3c(=O)[nH]2)cc(C)c1OCCO[Si](C)(C)C(C)(C)C>>C=Cc1ccc2nc(-c3cc(C)c(OCCO[Si](C)(C)C(C)(C)C)c(C)c3)[nH]c(=O)c2c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,,,,test
US20140343032A1,O=C1CC2COCC(C1)N2.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=C1CC2COCC(C1)N2S(=O)(=O)c1ccccc1[N+](=O)[O-],,ClCCl,,Cl,,test
US20140364433A1,C=CCOC(=O)N1CCC[C@H](C)[C@@H]1CNc1ccc(C(F)(F)F)cn1>>C[C@H]1CCCN[C@H]1CNc1ccc(C(F)(F)F)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,C1COCCN1,,test
US05834506,CC(C)(C)[Si](C)(C)Cl.O=C(CCc1ccccc1)c1ccc(OCCO)cc1>>CC(C)(C)[Si](C)(C)OCCOc1ccc(C(=O)CCc2ccccc2)cc1,,ClCCl,,c1c[nH]cn1,,test
US03940489,CC(C)(C)NCC(O)COc1ccc(Cl)cc1C#N>>CC(C)(C)NCC(O)COc1ccc(Cl)cc1CN,[Ni],CO,N,Cl,,test
US05110956,Cc1cc2c(cc1C=O)OCO2.[Li]C>>Cc1cc2c(cc1C(C)O)OCO2,,C1CCOC1,CCOCC,O,,test
US04997840,CC(=O)c1cc(F)ccc1N(C)C=O.O=S(=O)(Cl)Cl>>CN(C=O)c1ccc(F)cc1C(=O)CCl,,ClCCl,,O,,test
US05859007,BrC/C=C/c1ccccc1.CC(C)N(C(=O)CN1C(=O)CC(=O)N(c2ccccc2)c2ccccc21)c1ccccc1>>CC(C)N(C(=O)CN1C(=O)C(CC=Cc2ccccc2)C(=O)N(c2ccccc2)c2ccccc21)c1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20150126490A1,COCCc1cnc(N)cn1.O=C1CCC(=O)N1Br>>COCCc1cnc(N)c(Br)n1,,ClCCl,,,,test
US20050282812A1,CCOC(=O)N1c2ccc(C(F)(F)F)cc2N(C(C#N)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1CC.[N-]=[N+]=[N-].[NH4+]>>CCOC(=O)N1c2ccc(C(F)(F)F)cc2N(C(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nn[nH]n2)CC1CC,,CN(C)C=O,,[Cl-].[Na+],,test
US04992421,O=C(Cl)Cl.OCC(c1ccccc1)c1ccccc1>>O=C(Cl)OCC(c1ccccc1)c1ccccc1,,Cc1ccccc1,,,,test
US20130225551A1,CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(N/C(=C/C(C)=O)SC)nc21.CN(N)C(=O)OC(C)(C)C>>CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(Nc3cc(C)n(C)n3)nc21,,CC(=O)O,,O=CO,,test
US20150218141A1,COc1cccc(C2CCCN(CC(O)C(F)(F)F)C2)c1.ClCCl.O=C=Nc1ccc(Cl)cc1>>COc1cccc(C2CCCN(CC(OC(=O)Nc3ccc(Cl)cc3)C(F)(F)F)C2)c1.Cl,,ClCCl,,CC#N,,test
US20140275011A1,NCc1cccc(F)c1.O=[N+]([O-])c1cc(F)c(Br)cc1F>>O=[N+]([O-])c1cc(F)c(Br)cc1NCc1cccc(F)c1,,CCOCC,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100056515A1,CCC(CC)c1ccc(OC)c2nc(Cl)n(C)c12.Cc1cc(OC(F)(F)F)cc(CN(C)C)c1O.Cl>>CCC(CC)c1ccc(OC)c2nc(Oc3c(C)cc(OC(F)(F)F)cc3CN(C)C)n(C)c12.Cl,,CCOC(C)=O,,,,test
US20040019042A1,NO.O=C1c2ccc(S(=O)(=O)Nc3cccc(O)c3)cc2C(=O)c2cc(S(=O)(=O)Nc3cccc(O)c3)ccc21>>O=C1c2cc(S(=O)(=O)Nc3cccc(O)c3)ccc2C(=NO)c2ccc(S(=O)(=O)Nc3cccc(O)c3)cc21,,CO,,Cl,,test
US20100216788A1,BrCC1CC1.O=[N+]([O-])c1ccc(Oc2cccc(O)c2)c(Cl)c1>>O=[N+]([O-])c1ccc(Oc2cccc(OCC3CC3)c2)c(Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040225111A1,CCOC(=O)CCCOc1ccc(C[C@H](N)C(=O)OC(C)(C)C)cc1.Fc1nnnn1Cc1ccccc1>>CCOC(=O)CCCOc1ccc(C[C@H](Nc2nnnn2Cc2ccccc2)C(=O)OC(C)(C)C)cc1,,c1ccncc1,,,,test
US20130225591A1,O=C1CCC(=O)N1I.c1cn2cncc2s1>>Ic1ncn2ccsc12,,CN(C)C=O,,,,test
US06936602B1,COC(=O)C1=Cc2cc(-c3ccc(OCCOC(C)C)cc3)ccc2N(S(C)(=O)=O)CC1>>CC(C)OCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3S(C)(=O)=O)cc1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US03979390,CNC.O=C(c1ccccc1)C(F)CC(F)N1CCC(O)(c2ccc(Cl)cc2)CC1>>CN(C)C(CC(F)N1CCC(O)(c2ccc(Cl)cc2)CC1)C(=O)c1ccccc1,,c1ccccc1,,Cl,,test
US20100035874A1,CC(Br)C(=O)c1ccc(Cl)cc1Cl.Cc1nc(C)n(-c2c(C)n[nH]c2O)n1>>Cc1nc(C)n(-c2c(C)n[nH]c2OC(C)C(=O)c2ccc(Cl)cc2Cl)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040077633A1,CCOC(OCC)(OCC)OCC.Nc1ccc(O)cc1O>>CCOc1nc2ccc(O)cc2o1,,CCO,,Cl,CC(=O)[O-].[Na+],test
US05155130,C/C=C/C=O.O=Cc1cc(O)ccc1O>>CC1Oc2ccc(O)cc2C=C1C=O,,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US04921967,CCC1(C(=O)Cn2cncn2)CCCC1.O=CC(Cl)(Cl)Cl>>CCC1(C(=O)C(C(O)C(Cl)(Cl)Cl)n2cncn2)CCCC1,,C1CCOC1,,O,O=C([O-])[O-].[K+].[K+],test
US20150299192A1,CC(=O)N(C)c1nccc(-c2cc3c(n2C)CCN(C(=O)OC(C)(C)C)C3=O)n1>>CC(=O)N(C)c1nccc(-c2cc3c(n2C)CCNC3=O)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070270433A1,COc1ncnc2sc(NC(=O)N3CCC(N)CC3)nc12.O=C(Cl)c1ccc(F)c(C(F)(F)F)c1>>COc1ncnc2sc(NC(=O)N3CCC(NC(=O)c4ccc(F)c(C(F)(F)F)c4)CC3)nc12,,ClCCl,O,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20120071481A1,N[C@@H]1CCC[C@H](O)C1.O=C(Cl)c1noc(-c2ccc(C(F)(F)F)c(F)c2)c1CCl>>O=C(N[C@@H]1CCC[C@H](O)C1)c1noc(-c2ccc(C(F)(F)F)c(F)c2)c1CCl,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20080255136A1,NC(=O)c1cccc(N2CC(c3cccc(OCc4ccccc4)c3)CC2=O)c1>>NC(=O)c1cccc(N2CC(c3cccc(O)c3)CC2=O)c1,[Pd],CCO,,,,test
US06627651B1,CCCOc1cccc(Oc2ccc3c(c2)C=C(C(=O)OC)CCS3(=O)=O)c1>>CCCOc1cccc(Oc2ccc3c(c2)C=C(C(=O)O)CCS3(=O)=O)c1,,C1CCOC1,CO,Cl,O=C([O-])[O-].[K+].[K+],test
US20060234997A1,COc1ccc(CO)c([N+](=O)[O-])c1.ClP(Cl)(Cl)(Cl)Cl>>COc1ccc(CCl)c([N+](=O)[O-])c1,,ClC(Cl)Cl,,,,test
US20160068506A1,COc1cc(CC#N)cc(OC)c1OC.O=Cc1ccc2ccccc2n1>>COc1cc(/C(C#N)=C/c2ccc3ccccc3n2)cc(OC)c1OC,,CO,,C[O-].[Na+],,test
US05532240,CC(=O)OC(C)=O.c1cc2c(s1)CNCCC2>>CC(=O)N1CCCc2ccsc2C1,,ClC(Cl)Cl,,O,c1ccncc1,test
US20090048245A1,CCN(CC)CCN.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>CCN(CC)CCNS(=O)(=O)c1ccc([N+](=O)[O-])cc1,,ClCCl,ClCCl,CCN(CC)CC,,test
US06265434B1,CC(C)(C)OC(=O)C=C1CCN(Cc2ccccc2)CC1>>CC(C)(C)OC(=O)CC1CCN(Cc2ccccc2)CC1,O=[Pt],CCO,,[H][H],,test
US20040122057A1,CCOC(C(=O)NCc1ccc(C#N)cc1)c1c(F)ccc(C=O)c1F.Nc1ccccc1>>CCOC(C(=O)NCc1ccc(C#N)cc1)c1c(F)ccc(CNc2ccccc2)c1F,,CCO,,[BH4-].[Na+],,test
US20060074244A1,CS(=O)(=O)c1ccc(B(O)O)cc1.Cc1cccc(C#Cc2ccnc(Cl)c2)n1>>Cc1cccc(C#Cc2ccnc(-c3ccc(S(C)(=O)=O)cc3)c2)n1,,CCO,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],test
US04001244,CC(C)N(CCN)C(C)C.COc1ccc(C2c3cc(OC)c(OC)cc3CCN2C(=O)Cl)cc1OC>>COc1ccc(C2c3cc(OC)c(OC)cc3CCN2C(=O)NCCN(C(C)C)C(C)C)cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20160039821A1,CCN.Cn1cc(Br)c2cc(C(=O)O)[nH]c2c1=O>>CCNC(=O)c1cc2c(Br)cn(C)c(=O)c2[nH]1,,CS(C)=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130303433A1,CC(C)CC1=CCC(C=O)C(C)C1.[Li]C>>CC(C)CC1=CCC(C(C)O)C(C)C1,,CCOCC,,[Cl-].[NH4+],,test
US06472410B1,CC(C)(C)OC(=O)N1CCC(NC(=O)OCc2ccccc2)CC1.CCCI>>CCCN(C(=O)OCc1ccccc1)C1CCNCC1,,CN(C)C=O,,O,[H-].[Na+],test
US20080188528A1,COC(=O)[C@H](CCCNC(=O)OC(C)(C)C)NC(=O)c1cccn(Cc2cccc(I)c2)c1=O>>CC(C)(C)OC(=O)NCCC[C@H](NC(=O)c1cccn(Cc2cccc(I)c2)c1=O)C(=O)O,,CO,,C1CCOC1,[Na+].[OH-],test
US05091104,C=C(C)C.OCC(F)(F)F>>CC(C)(C)OCC(F)(F)F,,O,,O=S(=O)(O)O,,test
US20100160258A1,CC(F)(F)[C@@H]1CC[C@H](O)CC1.CS(=O)(=O)OS(C)(=O)=O>>CC(F)(F)[C@@H]1CC[C@H](OS(C)(=O)=O)CC1,,ClCCl,,CCN(CC)CC,O,test
US20030212111A1,CCNc1ccc(C#N)cc1N=C1SC(=C2Sc3cc(NC(=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)ccc3N2C)C(=O)N1Cc1ccccc1>>CCNc1ccc(C#N)cc1N=C1SC(=C2Sc3cc(NC(=N)N)ccc3N2C)C(=O)N1Cc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100137313A1,CC(=O)c1cccc(S(=O)(=O)Cl)c1.N>>CC(=O)c1cccc(S(N)(=O)=O)c1,,C1COCCO1,CCOC(C)=O,,,test
US20060069110A1,CC(N)Cc1cccc(CO)c1.CN(c1cccc(-c2cccc(F)c2)n1)c1ccnc(S(C)=O)n1>>CC(Cc1cccc(CO)c1)Nc1nccc(N(C)c2cccc(-c3cccc(F)c3)n2)n1,,CN1CCCC1=O,,,,test
US20140364620A1,CC1(C)OCC(CO)(Cn2ccnc2[N+](=O)[O-])CO1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCC2(Cn3ccnc3[N+](=O)[O-])COC(C)(C)OC2)cc1,,c1ccncc1,,O,[Cl-].[NH4+],test
US20020058652A1,O=S(=O)(c1ccc(F)cc1)N1CCCC1.Oc1cncc(Br)c1>>O=S(=O)(c1ccc(Oc2cncc(Br)c2)cc1)N1CCCC1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US05591762,CCCCc1nc2c(C)ccc(OCCCCCN3CNC4CC=CC=C43)c2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc2c(C)ccc(OCCCCCN3CNC4CC=CC=C43)c2n1Cc1ccc(-c2ccccc2C(=O)O)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110201643A1,O=C(NOC1CCCCO1)c1ccc2c(c1)CCNC2.O=C(O)CCc1cccnc1>>O=C(NOC1CCCCO1)c1ccc2c(c1)CCN(C(=O)CCc1cccnc1)C2,,CCN(CC)CC,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
US20050107364A1,CC(C)(C)CCC1(C)C(=O)C(C2=NS(=O)(=O)c3cc(NCl)ccc3N2)=C(O)c2ccccc21.CS(=O)(=O)Cl>>CC(C)(C)CCC1(C)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21,,CC(C)=O,,c1ccncc1,,test
US20070078129A1,Cc1ccc(N)c(C(C)(C)O)c1.O=C(Cl)Cl>>Cc1ccc2c(c1)C(C)(C)OC(=O)N2,,C1CCOC1,,CCN(CC)CC,Cc1ccccc1,test
US05952266,BrBr.O=C1CCSc2c(Cl)ccc(Cl)c21>>O=C1CCSc2c(Cl)cc(Br)c(Cl)c21,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US05418235,Cc1nc(N)sc1Br.Cl.SCCN1CCC(c2ccccc2)CC1>>Cc1nc(N)sc1SCCN1CCC(c2ccccc2)CC1.Cl,,CN(C)C=O,CO,O=C([O-])[O-].[K+].[K+],,test
US20100056576A1,CO.O=C(O)c1ccc(F)c(C2=CCC3(CC2)OCCO3)n1>>COC(=O)c1ccc(F)c(C2=CCC3(CC2)OCCO3)n1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US03966816,NC1CC1.O=[N+]([O-])c1cc(C(F)(F)F)c(Cl)c([N+](=O)[O-])c1Cl>>O=[N+]([O-])c1cc(C(F)(F)F)c(Cl)c([N+](=O)[O-])c1NC1CC1,,C1CCCCC1,,,,test
US20030229089A1,COc1ccc(CNc2nc(S(C)=O)nc(N3CCC(O)CC3)c2C(=O)OCCOCc2ccccc2)cc1Cl.OC[C@@H]1CCCN1>>COc1ccc(CNc2nc(N3CCCC3CO)nc(N3CCC(O)CC3)c2C(=O)OCCOCc2ccccc2)cc1Cl,,O,,CCN(CC)CC,CN(C)C=O,test
US03957784,CCO.CCOC(=O)c1cnc(-c2cccc(N)c2)nc1O>>CC(=O)Nc1cccc(-c2ncc(C(=O)O)c(O)n2)c1,,O,,[K+].[OH-],,test
US20120245181A1,C=CCC1(NN)CCOC2(CCCC2)C1.CN(C)C=CC=O>>C=CCC1(n2cccn2)CCOC2(CCCC2)C1,,CC(C)O,,CCN(CC)CC,,test
US20130190295A1,BrCCc1ccccc1.CN1CCc2[nH]c3ccc(Cl)cc3c2CC1>>CN1CCc2c(n(CCc3ccccc3)c3ccc(Cl)cc23)CC1,,C1CCOC1,,O,[Na+].[OH-],test
US20110294853A1,CCCCc1ccc(C(=O)Cl)cc1.COC(=O)c1cc([N+](=O)[O-])ccc1N>>CCCCc1ccc(C(=O)Nc2ccc([N+](=O)[O-])cc2C(=O)OC)cc1,,CO,,CC#N,CCN(CC)CC,test
US20160251339A1,COc1ccc(S(=O)(=O)Cl)cc1N1CCN(C(=O)C(Cl)(Cl)Cl)CC1.Fc1cccc2cc[nH]c12>>COc1ccc(S(=O)(=O)n2ccc3cccc(F)c32)cc1N1CCN(C(=O)C(Cl)(Cl)Cl)CC1,,C1CCOC1,,[H-].[Na+],,test
US20160272662A1,Cc1ccc(S(=O)(=O)OCCCCCCCO)cc1.O=C=NS(=O)(=O)Cl>>Cc1ccc(S(=O)(=O)OCCCCCCCOS(N)(=O)=O)cc1,,ClCCl,,CCN(CC)CC,O=CO,test
US20150087646A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NNc1ccc(C(F)(F)F)nc1>>CC(C)(C)OC(=O)NNc1ccc(C(F)(F)F)nc1,,O,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US20070112077A1,COC(=O)[C@H](C)COCOCc1ccccc1>>C[C@H](CO)COCOCc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080181866A1,CC(C)(C)OC(=O)N1CCCC([C@H]2SCC(C(=O)Nc3nc(-c4ccc(C(=O)NC5CC5)cc4)cs3)N2C(=O)OCc2ccccc2)C1>>O=C(NC1CC1)c1ccc(-c2csc(NC(=O)C3CS[C@H](C4CCCNC4)N3C(=O)OCc3ccccc3)n2)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20070105852A1,C=C[Sn](CCCC)(CCCC)CCCC.CCOC(=O)c1sc(SC)c(C#N)c1-c1ccc(I)cc1>>C=Cc1ccc(-c2c(C(=O)OCC)sc(SC)c2C#N)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,[Cl-].[Li+],,test
US04552703,C=CCC1=C(C)[C@H](O)CC1=O.O=[N+]([O-])O>>C=CCC1=C(C)[C@H](O[N+](=O)[O-])CC1=O,,ClC(Cl)Cl,,CC(=O)OC(C)=O,,test
US20110245310A1,CC(C)c1nc2c(n1Cc1ccc(Cl)c(Cl)c1)C(=O)CC2>>CC(C)c1nc2c(n1Cc1ccc(Cl)c(Cl)c1)C(O)CC2,,CO,ClCCl,[BH4-].[Na+],,test
US06437167B1,N#Cc1c(Cl)c(Cl)c(Cl)c(C#N)c1Cl.NC1CCCCC1N>>N#Cc1c(Cl)c(Cl)c(NC2CCCCC2N)c(C#N)c1Cl,,CC#N,,,,test
US20110195917A1,CCc1ccc(Cc2cc([C@@]3(O)O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)cc(OC)c2C#N)cc1>>CCc1ccc(Cc2cc([C@@]3(O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc(OC)c2C#N)cc1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20110319394A1,CC1(C)OB(c2ccc(-n3c(=O)n(COCC[Si](C)(C)C)c4cccnc43)cc2)OC1(C)C.Cc1nc2c(Br)cccc2n1Cc1ccccc1>>Cc1nc2c(-c3ccc(-n4c(=O)n(COCC[Si](C)(C)C)c5cccnc54)cc3)cccc2n1Cc1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1CCOC1,O=C([O-])[O-].[Na+].[Na+],test
US20150011753A1,CC(=O)OCCCl.COC(=O)c1ccccc1O>>CCOC(=O)COc1ccccc1C(=O)OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040157886A1,CCOC(=O)C(C)Br.c1ccc(CC2CCNCC2)cc1>>CCOC(=O)C(C)N1CCC(Cc2ccccc2)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120129852A1,N#Cc1c(-c2ccc(Oc3ccccc3)cc2)cc(Cl)nc1Cl.Oc1ccccc1>>N#Cc1c(-c2ccc(Oc3ccccc3)cc2)cc(Oc2ccccc2)nc1Cl,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090186870A1,CN(C)[C@@H]1CCNC1.NC(=O)c1cc(F)ccc1Cl>>CN(C)[C@@H]1CCN(c2ccc(Cl)c(C(N)=O)c2)C1,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20160075711A1,COC(=O)c1nc(Cl)ccc1Br>>OCc1nc(Cl)ccc1Br,,CO,,[BH4-].[Na+],,test
US20040185520A1,C1CCOC1.NN.O=C1c2cccc(Cl)c2C(=O)c2cccc(Cl)c21>>O=C1CC(Cl)=c2cc3ccc4c(c3cc2C1)C=NN=4,,C1CCOC1,,CCN(C(C)C)C(C)C,O,test
US20150045349A1,COc1ccn(C(C)C2CC2)c(=O)c1C#N.O=C1CCC(=O)N1Br>>COc1c(Br)cn(C(C)C2CC2)c(=O)c1C#N,,CN(C)C=O,,,,test
US20130102576A1,O=C(O)CN1C(=O)c2cccc([N+](=O)[O-])c2C1=O.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>O=C(CN1C(=O)c2cccc([N+](=O)[O-])c2C1=O)O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1,CN(C)c1ccncc1,CN(C)C=O,,ClCCCl,,test
US05053408,Nc1cccnc1Cl.S=C=S>>S=c1[nH]c2cccnc2s1,,CN(C)C=O,,,,test
US20110288299A1,CCOC(=O)c1cnc(Nc2cc3c4c(c2)CCCC4(C)CCC3)nc1>>CC12CCCc3cc(Nc4ncc(C(=O)O)cn4)cc(c31)CCC2,,CCO,,Cl,[Na+].[OH-],test
US20030078299A1,BrC(Br)(Br)Br.CCCCCCCCCCCCCCCCCCO>>CCCCCCCCCCCCCCCCCCBr,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070004675A1,CCOC(=O)CC(=O)OCC.CCOC(Nc1ccccc1)C(F)(F)F>>CCOC(=O)C(C(=O)OCC)C(Nc1ccccc1)C(F)(F)F,,C1CCOC1,,Cl,[H-].[Na+],test
US20130338142A1,COc1cc([N+](=O)[O-])ccc1N1CCN(C[C@H](C)O)CC1>>COc1cc(N)ccc1N1CCN(C[C@H](C)O)CC1,[Pd],CCO,,,,test
US20110077252A1,CCOc1cc(C(F)(F)F)nc(-c2ccc(N)cn2)n1.O=C(Cl)CCl>>CCOc1cc(C(F)(F)F)nc(-c2ccc(NC(=O)CCl)cn2)n1,,C1CCOC1,,CCN(CC)CC,,test
US04451474,CC(O)(Cl)C(=O)O.Oc1ccc(Cl)cc1>>O=C(O)C(O)COc1ccc(Cl)cc1,,[Na+],[OH-],Cl,,test
US20030176477A1,CC(=Cc1ccccc1)C(=O)Cl.NNC(=O)c1snc(Cl)c1Cl>>Cc1c(-c2ccccc2)[nH]n(C(=O)c2snc(Cl)c2Cl)c1=O,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20080269193A1,CC1(C)CC(=O)c2c(C(F)(F)F)cn(-c3ccc(C#N)c(N[C@@H]4CCC[C@H]4O)c3)c2C1.OO>>CC1(C)CC(=O)c2c(C(F)(F)F)cn(-c3ccc(C(N)=O)c(N[C@H]4CCC[C@@H]4O)c3)c2C1,,CCO,CS(C)=O,[Na+].[OH-],,test
US06316632B1,CC(=O)Nc1cccnc1Cl.OB(O)c1ccccc1>>CC(=O)Nc1cccnc1-c1ccccc1.Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20030207882A1,N#Cc1ccc(F)cc1C(F)(F)F.Sc1ccc2cc(Br)ccc2c1>>N#Cc1ccc(Sc2ccc3cc(Br)ccc3c2)cc1C(F)(F)F,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,,test
US20120015963A1,Clc1ncc(Br)c(Cl)n1.O=CN1CCOCC1>>O=Cc1cnc(Cl)nc1Cl,,C1CCOC1,,CCOCC,Cl,test
US20110105502A1,O=S1(=O)CCCO1.Oc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)=NCC2>>O=S(=O)(O)CCCOc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)=NCC2,,CN(C)C=O,,[H-].[Na+],,test
US20100298336A1,BrP(Br)Br.OCc1c(Cl)cncc1Cl>>Br.Clc1cncc(Cl)c1CBr,,ClCCl,,,,test
US05521173,O=C(Cl)c1ccc(-c2ccccc2)cc1.c1ccc2c(c1)Cn1nccc1CN2>>O=C(c1ccc(-c2ccccc2)cc1)N1Cc2ccnn2Cc2ccccc21,,ClCCl,,CCN(CC)CC,,test
US20030232852A1,Cc1cc(NCC(C)C)c([N+](=O)[O-])c(Cl)n1>>Cc1cc(NCC(C)C)c(N)c(Cl)n1,[Pt],Cc1ccccc1,,[H][H],,test
US20110294822A1,C[C@@H](NC(=O)C(F)(F)F)C(=O)O.O=C(Cl)C(=O)Cl>>C[C@@H](NC(=O)C(F)(F)F)C(=O)Cl,,ClCCl,,c1ccncc1,,test
US05070196,CC(C)CCN.Cl.ClCCCN1CCCCC1>>CC(C)CCNCCCN1CCCCC1.Cl.Cl,,CCO,,,,test
US04720586,CC(=O)Cl.CCCc1c(C=O)ccc(OC)c1O>>CCCc1c(C=O)ccc(OC)c1OC(C)=O,,CN(C)C=O,,[H-].[Na+],,test
US20040058964A1,BrBr.Cc1cc(OCc2cccc(Cl)c2)cc(=O)n1Cc1ccccc1>>Cc1cc(OCc2cccc(Cl)c2)c(Br)c(=O)n1Cc1ccccc1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20080293775A1,COC(=O)c1ccc(Cl)cc1Oc1ccc(S(C)(=O)=O)cc1Cl>>CS(=O)(=O)c1ccc(Oc2cc(Cl)ccc2C(=O)O)c(Cl)c1,,C1CCOC1,,CO,[Na+].[OH-],test
US20090018122A1,COCCc1nc2c(N)nc3cc(OCc4cccc([N+](=O)[O-])c4)ccc3c2n1CC(C)(C)O>>COCCc1nc2c(N)nc3cc(OCc4cccc(N)c4)ccc3c2n1CC(C)(C)O,[Pt],CO,,CCO,,test
US20160031873A1,C[C@H](N)CC(N)=O.NC(=O)c1cc(Cl)nc(Cl)n1>>C[C@H](Nc1cc(C(N)=O)nc(Cl)n1)C(N)=O,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20110118230A1,Brc1ccc(-c2ccccn2)cc1.CCI>>CCN1CC=CCC1c1ccc(Br)cc1,,CN(C)C=O,CO,[BH4-].[Na+],,test
US04906621,CCOC(=O)c1cc(CCO)ccn1>>CCOC(=O)C1CC(CCO)CCN1,O=[Pt],CC(=O)O,,,,test
US06294538B1,C1CNCCN1.CCCC(=O)O[C@@H](C)c1nccc(O)n1>>CCCC(=O)O[C@@H](C)c1nccc(N2CCNCC2)n1,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20020137766A1,CCCCS(=O)(=O)Cl.CNC1C2CCC1CN(CCCNc1ccc(C#N)cc1)C2>>CCCCS(=O)(=O)N(C)C1C2CCC1CN(CCCNc1ccc(C#N)cc1)C2,,CC#N,ClC(Cl)Cl,O=C([O-])[O-].[K+].[K+],,test
US20150087600A1,Clc1ncccn1.O=C(NC1CC(F)(F)C1)[C@H](c1ccccc1Cl)N(C(=O)[C@@H]1C[C@@H](O)CN1)c1cccc(F)c1>>O=C(NC1CC(F)(F)C1)[C@H](c1ccccc1Cl)N(C(=O)[C@@H]1C[C@@H](O)CN1c1ncccn1)c1cccc(F)c1,,CCO,,O,O=C([O-])[O-].[K+].[K+],test
US20100093730A1,CCOC(=O)CN1CCCC(c2ccc(F)cc2)(c2ccc(F)cc2)C1=O>>O=C(O)CN1CCCC(c2ccc(F)cc2)(c2ccc(F)cc2)C1=O,,CCO,O,[Li+].[OH-],,test
US20120190666A1,Cc1nc(Cl)cc(-c2c(Cl)nc3ccc(Br)cn23)n1.N>>Cc1nc(N)cc(-c2c(Cl)nc3ccc(Br)cn23)n1,,CC(C)O,,CO,,test
US20070142357A1,C[C@@H]1CN(C(=O)C(F)(F)F)CCc2ccc(Cl)c(F)c21>>C[C@@H]1CNCCc2ccc(Cl)c(F)c21,,CO,,[Na+].[OH-],,test
US20090264420A1,CCC(C)(C)C(Br)C(=O)Cl.Fc1cccc(CNCCc2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)c1>>CCC(C)(C)C1C(=O)N(Cc2cccc(F)c2)CCc2cncn21,,CN(C)C=O,ClCCl,CCN(CC)CC,,test
US05041638,CCOC(=O)CCCCC(CO)Cc1ccc(C(=O)OCC)cc1>>CCOC(=O)CCCCC(C=O)Cc1ccc(C(=O)OCC)cc1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20130324551A1,NC(=S)C1CCOCC1.O=C(CBr)c1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(-c2csc(C3CCOCC3)n2)c1,,CCO,,,,test
US20140275047A1,C=CC(=O)Cl.Cc1ccc(C(C)C)c(NC(N)=S)c1.O=C=NCCc1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1>>Cc1ccc(C(C)C)c(N2C(=O)CCS/C2=N\C(=O)NCCc2ccc(-c3ncn(-c4ccc(OC(F)(F)F)cc4)n3)cc2)c1,,CC#N,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050261333A1,Nc1ncc(Cl)c(Cl)c1N.O=C(O)c1ccc(N2CCOCC2)cc1>>Clc1cnc2nc(-c3ccc(N4CCOCC4)cc3)[nH]c2c1Cl,,O=P(Cl)(Cl)Cl,,,,test
US20150266874A1,CCOC(=O)c1cn(COCC[Si](C)(C)C)nc1-c1nc(-c2ccccc2)cs1>>C[Si](C)(C)CCOCn1cc(C(=O)O)c(-c2nc(-c3ccccc3)cs2)n1,,C1COCCO1,,[Na+].[OH-],,test
US20140357858A1,Nc1cccc(C2=NCC(=O)Nc3c2ccc2ccccc32)c1.O=S(=O)(Cl)c1ccccc1>>O=C1CN=C(c2cccc(NS(=O)(=O)c3ccccc3)c2)c2ccc3ccccc3c2N1,,c1ccncc1,,,,test
US20050049274A1,C=Cc1ccc(N)c(C(=O)c2ccccc2)c1.Cc1cc(CC(=O)Cl)on1>>C=Cc1ccc2[nH]c(=O)c(-c3cc(C)no3)c(-c3ccccc3)c2c1,,ClCCl,,CCN(CC)CC,,test
US04820698,C=O.CCCCCCCOP(=O)(CP(=O)(OCCCCCCC)OCCCCCCC)OCCCCCCC>>C=C(P(=O)(OCCCCCCC)OCCCCCCC)P(=O)(OCCCCCCC)OCCCCCCC,,CO,,CCNCC,,test
US20160009744A1,Cc1cccc(B(O)O)c1.Cc1oc(C=O)cc1CBr>>Cc1cccc(Cc2cc(C=O)oc2C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Cs+].[Cs+],test
US20050250797A1,COCCC#Cc1cc(Cl)c(N)c2c1OCO2.COc1cc2c(Cl)ncnc2cc1OCCCN1CCN(CCF)CC1>>COCCC#Cc1cc(Cl)c(Nc2ncnc3cc(OCCCN4CCN(CCF)CC4)c(OC)cc23)c2c1OCO2,,CN(C)C=O,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US08476253B2,CN(CCCCCC(=O)N(C)CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1)Cc1cccc(C(=O)N(C)CCCN(C)C(=O)CO[C@H]2Cc3ccccc3C23CCN(CC[C@@]2(c4ccc(F)cc4)CN(C(=O)c4cc(C(F)(F)F)cc(C(F)(F)F)c4)CO2)CC3)c1.Cl.ClCCl>>CN(CCCCCC(=O)N(C)CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1)Cc1cccc(C(=O)N(C)CCCN(C)C(=O)CO[C@H]2Cc3ccccc3C23CCN(CC[C@@]2(c4ccc(F)cc4)CN(C(=O)c4cc(C(F)(F)F)cc(C(F)(F)F)c4)CO2)CC3)c1.Cl.Cl.Cl,,ClCCl,,C1COCCO1,,test
US08129361B2,CC(C)(C)OC(=O)NC1(CCc2ccc(OCCCc3ccc4c(c3)OCO4)c(C(F)(F)F)c2)COC(C)(C)OC1.Cl>>Cl.NC(CO)(CO)CCc1ccc(OCCCc2ccc3c(c2)OCO3)c(C(F)(F)F)c1,,CCO,,,,test
US04178449,CC(=CN(C)C)C(=O)c1cccc(C(F)(F)F)c1.CCc1[nH]nc(N)c1C#N>>CCc1nn2c(-c3cccc(C(F)(F)F)c3)c(C)cnc2c1C#N,,CC(=O)O,,,,test
US20150141406A1,CC1(C)OBOC1(C)C.C[C@H]1COCCN1c1ccc(Br)cc1>>C[C@H]1COCCN1c1ccc(B2OC(C)(C)C(C)(C)O2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,CCN(CC)CC,O,test
US20090099156A1,CCBr.O=C(OCc1ccccc1)N1CCN(C[C@@H]2CCCNC2)CC1>>CCN1CCC[C@@H](CN2CCN(C(=O)OCc3ccccc3)CC2)C1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050014840A1,CCCCCBr.COc1ccc(S(=O)(=O)NCCO)cc1>>CCCCCN(CCO)S(=O)(=O)c1ccc(OC)cc1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20030060461A1,CCOC(=O)c1nc2cc(OC)c(OC)c(OC)c2s1>>COc1cc2nc(CO)sc2c(OC)c1OC,,CO,,[BH4-].[Na+],,test
US20040157804A1,CC(=O)O.CCOC(=O)C(C)OP(=O)(CCNC(=O)OCc1ccccc1)Oc1ccccc1>>CC(=O)O.CCOC(=O)C(C)OP(=O)(CCN)Oc1ccccc1,[Pd],CCO,,,,test
US20110009391A1,CCS(=O)(=O)N1CCN(c2ccc(N3CCN(C(=O)OC(C)(C)C)c4ccccc43)nc2)CC1>>CCS(=O)(=O)N1CCN(c2ccc(N3CCNc4ccccc43)nc2)CC1,,C1COCCO1,,Cl,,test
US20140155391A1,O=Cc1ccc(C(=O)O)cc1OCC1CC1.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>O=Cc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1OCC1CC1,CN(C)c1ccncc1,ClCCl,O,CCN=C=NCCCN(C)C,Cl,test
US20080287446A1,COC(=O)[C@H](CCSc1ccccn1)NC(=O)OC(C)(C)C>>COC(=O)[C@@H](N)CCSc1ccccn1,,C1CCOC1,,CS(=O)(=O)O,,test
US20120301401A1,O=C(COCCO)OCc1ccccc1.O=C(O)COCCOC1CCCCO1>>O=C(COCCOC1CCCCO1)OCCOCC(=O)OCc1ccccc1,CN(C)c1ccncc1,,,CC(C)N=C=NC(C)C,,test
US20120208798A1,CCOC(=O)c1cn(-c2ccc3c(c2)[C@H](NC(=O)OC(C)C)C[C@H](C)N3C(C)=O)cn1>>CC(=O)N1c2ccc(-n3cnc(CO)c3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C,,C1CCOC1,,[BH4-].[Li+],,test
US20080096860A1,CC(C)I.CC1(C)OCC(CO)O1>>CC(C)OC[C@@H]1COC(C)(C)O1,,CS(C)=O,O,[K+].[OH-],,test
US20130324576A1,CO.Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Oc2ncc(Cl)cc2F)CC1>>COc1cc(Cl)cnc1OC1CCN(S(=O)(=O)c2c(C)nn(C)c2C)CC1,,CO,,C[O-].[Na+],,test
US05578620,CC(=O)COc1ccc(CC2SC(=O)NC2=O)cc1.NCC(O)COCc1ccccc1>>CC(COc1ccc(CC2SC(=O)NC2=O)cc1)NCC(O)COCc1ccccc1,,CO,,[BH3-]C#N.[Na+],,test
US20130022573A1,CO[C@@H]1CCC=Cc2ccnc(c2)COC(=O)[C@@H]2CCCN(N2)C(=O)[C@H](Cc2cccc(O[Si](C)(C)C(C)(C)C)c2)NC(=O)[C@H](C(C)C)NC(=O)[C@@H]1C>>CO[C@@H]1CCC=Cc2ccnc(c2)COC(=O)[C@@H]2CCCN(N2)C(=O)[C@H](Cc2cccc(O)c2)NC(=O)[C@H](C(C)C)NC(=O)[C@@H]1C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05210092,C[Sn](C)(C)N=[N+]=[N-].Cc1ccc(-c2cc(Cl)sc2C#N)cc1>>Cc1ccc(-c2cc(Cl)sc2-c2nnn[nH]2)cc1,,Cc1ccccc1C,,,,test
US20160090374A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H]1CCCN(c2nc(Cl)nc3cccnc23)C1>>CC(C)(C)OC(=O)N[C@@H]1CCCN(c2nc(Cl)nc3cccnc23)C1,,C1COCCO1,,CCN(CC)CC,,test
US05294734,CCOC(=O)COCCCC(=O)Cl>>CCOC(=O)COCCCC=O,[Pd],C1CCOC1,,Cc1cccc(C)n1,,test
US04499097,CC(=O)c1nc(-c2ccncc2)[nH]c1C.NO>>CC(=NO)c1nc(-c2ccncc2)[nH]c1C,,O,,Cl,CC(=O)[O-].[Na+],test
US20130053383A1,CN1CCN(c2cc(B3OC(C)(C)C(C)(C)O3)ccn2)CC1.Cc1cc(C)c(CNC(=O)c2cc(Br)cc3c2c(C)nn3C(C)C)c(=O)[nH]1>>Cc1cc(C)c(CNC(=O)c2cc(-c3cccc(N4CCN(C)CC4)n3)cc3c2c(C)nn3C(C)C)c(=O)[nH]1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20060293540A1,CC(=O)ONC(=N)c1ccc(-c2ccc(-c3ccc(C(=N)NOC(C)=O)o3)o2)cc1>>CC(=O)O.N=C(N)c1ccc(-c2ccc(-c3ccc(C(=N)N)o3)o2)cc1,[Pd],CC(=O)O,,CCO,,test
US20040157741A1,CC(C)(C)[Si](C)(C)Oc1ccc(S(N)(=O)=O)cc1.O=C(O)c1ccc(Cl)cc1Cl>>CC(C)(C)[Si](C)(C)Oc1ccc(S(=O)(=O)NC(=O)c2ccc(Cl)cc2Cl)cc1,,ClCCl,,ClCCCl,,test
US20150045368A1,CC(C)(C)OC(=O)NC(c1ccccc1F)C(C)(C)O>>CC1(C)OC(=O)NC1c1ccccc1F,,C1CCOC1,CCCCCC,CCOC(C)=O,CC(C)(C)[O-].[K+],test
US20160221945A1,Cc1cc(-c2cnc(C(F)(F)F)nc2)cc(N2C(=O)c3ccccc3C2=O)n1>>Cc1cc(-c2cnc(C(F)(F)F)nc2)cc(N)n1,,CO,,NN,O,test
US05015777,CC(=O)c1ccccc1.CCCCCCCCCCCCCCCCCC(=O)OC>>CC(=O)CCCCCCCCCCCCCCCCCC(=O)c1ccccc1,,Cc1ccccc1C,,C[O-].[Na+],,test
US20100093703A1,CC(=O)OC(C)=O.NCCCNc1ccc(-n2ccc3cc(N(CC(=O)O)S(=O)(=O)c4cc(Cl)cc(Cl)c4)ccc32)nn1>>CC(=O)NCCCNc1ccc(-n2ccc3cc(N(CC(=O)O)S(=O)(=O)c4cc(Cl)cc(Cl)c4)ccc32)nn1,,C1CCOC1,,c1ccncc1,,test
US20070054924A1,COC(=O)c1nn[nH]c1N(C)S(C)(=O)=O>>CN(c1[nH]nnc1C(=O)O)S(C)(=O)=O,,C1CCOC1,,[Na+].[OH-],,test
US04319919,CC(C)(C)c1ccc(O)cc1.CCCCl>>CCCOc1ccc(C(C)(C)C)cc1,,CCO,,[Na],,test
US20070078124A1,CN(C)CCCOCc1onc2c1-c1ccccc1Sc1ccc(Cl)cc1-2.O>>ON=C1Cc2ccccc2Oc2ccccc21,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20120252779A1,CS(=O)(=O)Cl.O=[N+]([O-])c1cn[nH]c1>>CS(=O)(=O)n1cc(N)cn1,,ClCCl,,CCN(CC)CC,O,test
US04857507,CC(C)S.CCOC(=O)CBr>>CCOC(=O)CSC(C)C,,CCO,,[Na],,test
US20040063954A1,CCC(=O)Cl.N#CC=C1CCN(c2ccc(N3C[C@H](CN)OC3=O)cc2F)CC1>>CCC(=O)NC[C@H]1CN(c2ccc(N3CCC(=CC#N)CC3)c(F)c2)C(=O)O1,,c1ccncc1,,,,test
US20110144136A1,CCC[C@H](C)Oc1nc(N)c2nc(OC)n(CCC3CCCNC3)c2n1>>CCC[C@H](C)Oc1nc(N)c2[nH]c(=O)n(CCC3CCCNC3)c2n1,,CO,,C1COCCO1,Cl,test
US20160002224A1,C[Si](C)(C)CCOCn1c(Cl)cc2nc(-c3ccc(-c4ccccc4)cc3)c(Cl)cc21.OC1CCC2(CC1)OCCO2>>Clc1cc2[nH]c(OC3CCC4(CC3)OCCO4)cc2nc1-c1ccc(-c2ccccc2)cc1,,CN1CCCC1=O,,[H-].[Na+],,test
US06166006,CCOC(=O)CCCBr.O=CNc1ccc(Br)cc1C=O>>CCOC(=O)CCCN(C=O)c1ccc(Br)cc1C=O,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20110144105A1,CC(C)(C)[Si](C)(C)N1CCc2cc(Br)cnc21.CCSSCC>>CCSc1cnc2c(c1)CCN2[Si](C)(C)C(C)(C)C,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20100075948A1,CC(C)(C)OC(=O)CN.CC(C)(CC=O)c1ccccc1>>CC(C)(C)OC(=O)C/N=C/CC(C)(C)c1ccccc1,,ClCCl,,,,test
US20040157922A1,CC(C)(C)OC(=O)COc1ccccc1N.O=C=NC(=O)c1ccc(F)cc1Cl>>CC(C)(C)OC(=O)COc1ccccc1NC(=O)NC(=O)c1ccc(F)cc1Cl,,CC#N,,,,test
US20090247588A1,CCOC(=O)c1cc(Br)c(=O)[nH]c1C(F)(F)F.OCC(F)(F)F>>CCOC(=O)c1cc(Br)c(OCC(F)(F)F)nc1C(F)(F)F,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100130738A1,COC(=O)C(C)(C)C(=O)c1ccc(OC)c2sc(C(F)(F)F)cc12.NN>>COc1ccc(C2=NNC(=O)C2(C)C)c2cc(C(F)(F)F)sc12,,CCO,,O,,test
US20100249085A1,O=[N+]([O-])c1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)n[nH]1>>Nc1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)n[nH]1,[Pd],CCOC(C)=O,,,,test
US20020002177A1,CCCOc1ccc2c(c1)C(c1ccc(OC)cc1O)CC2c1ccc2c(c1)OCO2.CCOC(=O)CBr>>CCCOc1ccc2c(c1)C(c1ccc(OC)cc1OCC(=O)OCC)CC2c1ccc2c(c1)OCO2,,CN(C)C=O,,[H-].[Na+],,test
US20040259903A1,CO.COc1cc2c(cc1OC)C1CC(NC(=O)OC(C)(C)C)C(C(=O)N3CCCC3)CN1CC2.ClCCl.[NH4+].[OH-]>>CO.COc1cc2c(cc1OC)C1CC(N)C(C(=O)N3CCCC3)CN1CC2.ClCCl.[NH4+].[OH-],,Cl,,,,test
US20150126523A1,FC(F)(F)CNCCCCl.O=C(Cl)Oc1ccccc1>>O=C(Oc1ccccc1)N(CCCCl)CC(F)(F)F,,c1ccncc1,,ClCCl,,test
US20110257100A1,CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)O)C(C)(C)CCC1.O=C(Nc1ccc(Oc2ccnc3cc(-c4ccc(CN5CCNCC5)cn4)sc23)c(F)c1)NC1CC1>>CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)N2CCN(Cc3ccc(-c4cc5nccc(Oc6ccc(NC(=O)NC7CC7)cc6F)c5s4)nc3)CC2)C(C)(C)CCC1,,CN(C)C=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20100137276A1,CCOC(=O)C(F)(F)F.O=C1CCOCC1>>O=C1CCOCC1C(=O)C(F)(F)F,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20060235031A1,O=C1NC(=O)c2ccccc21.OCc1nccnc1Cl>>O=C1c2ccccc2C(=O)N1Cc1nccnc1Cl,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05344843,COC(=O)C(=O)c1ccc(OCCOc2ccc3ccccc3c2)cc1.OCCNCCO>>O=C(C(=O)N(CCO)CCO)c1ccc(OCCOc2ccc3ccccc3c2)cc1,,C1CCOC1,CO,,,test
US20080249102A1,CC1(C)O[C@@H]2Cc3ccccc3[C@@H]2N1C(=O)[C@](O)(CCO)Cc1ccccc1>>CC1(C)O[C@@H]2Cc3ccccc3[C@@H]2N1C(=O)[C@](O)(CC=O)Cc1ccccc1,,CCOCC,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US06329396B1,CC(C)(C)OC(=O)N1CCC[C@H](N)[C@@H]1c1ccccc1.CC(F)(F)c1ccc(OC(F)(F)F)c(C=O)c1>>CC(C)(C)OC(=O)N1CCC[C@H](NCc2cc(C(C)(F)F)ccc2OC(F)(F)F)[C@@H]1c1ccccc1,,ClCCl,,CC(=O)O,[Na+].[OH-],test
US20140323518A1,CC1(C)NC(c2cc(C#N)cc(-c3ccc(O)cc3)c2-c2cc(F)cc(F)c2)=NO1>>N#Cc1cc(C(N)=NO)c(-c2cc(F)cc(F)c2)c(-c2ccc(O)cc2)c1,,CCO,,Cl,O=C([O-])O.[Na+],test
US20100286145A1,COC(=O)c1cc(CNC[C@@H](O)[C@H](Cc2ccccc2)NC(=O)c2cccc(C(=O)N(C)Cc3nc(C)cs3)c2)cc(N(C)S(C)(=O)=O)c1>>Cc1csc(CN(C)C(=O)c2cccc(C(=O)N[C@@H](Cc3ccccc3)[C@H](O)CNCc3cc(C(=O)O)cc(N(C)S(C)(=O)=O)c3)c2)n1,,C1CCOC1,CO,[Na+].[OH-],,test
US20090048452A1,CC(C)(C)OC(=O)N[C@@H](C(=O)O)c1ccc(O)cc1.CC(C)(C)[Si](C)(C)OCCN(CCO[Si](C)(C)C(C)(C)C)C(=O)CCl>>CC(C)(C)OC(=O)N[C@@H](C(=O)O)c1ccc(OCC(=O)N(CCO[Si](C)(C)C(C)(C)C)CCO[Si](C)(C)C(C)(C)C)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20050187266A1,Cc1oc(-c2ccccc2)nc1CCCO>>Cc1oc(-c2ccccc2)nc1CCC=O,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20110021500A1,CCOC(=O)c1cc(Nc2ccc3c(c2)CC2(C3)C(=O)Nc3ncccc32)ncn1.Cl>>Cl.O=C(O)c1cc(Nc2ccc3c(c2)CC2(C3)C(=O)Nc3ncccc32)ncn1,,CCO,,[Li+].[OH-],,test
US04002751,CNN.O=c1c(Cl)c(Cl)cnn1-c1cccc(C(F)(F)F)c1>>CN(N)c1cnn(-c2cccc(C(F)(F)F)c2)c(=O)c1Cl,,CO,,O,,test
US20140046069A1,O=C1c2ccccc2C(=O)N1Cc1cnc(N2CCC(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1C(F)(F)F>>NCc1cnc(N2CCC(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)(C(F)(F)F)C2)cc1C(F)(F)F,,CCO,,NN,O,test
US20130220415A1,O=C1C=c2ccccc2=N1.O=C1Nc2cc(Br)ccc2C1=O>>O=C1Nc2ccccc2/C1=C1\C(=O)Nc2ccccc21,,CC(=O)O,,Cl,,test
US20100249119A1,CC(C)(C)OC(=O)Nc1cccc(Oc2ccc3nc(N)nn3c2)c1.O=C(Cl)C1CC1>>CC(C)(C)OC(=O)Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)c1,,CC(=O)N(C)C,CCOC(C)=O,,,test
US20150005289A1,CC(C)(C)OC(=O)N1CC2(CCNCC2)C1.O=[N+]([O-])c1ccc(F)cn1>>CC(C)(C)OC(=O)N1CC2(CCN(c3ccc([N+](=O)[O-])nc3)CC2)C1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070265309A1,C=O.Fc1ccc([C@H]2CNCCN2Cc2cncc(Br)c2)cc1>>CN1CCN(Cc2cncc(Br)c2)[C@@H](c2ccc(F)cc2)C1,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20140235629A1,CC(C)(C)OC(=O)N[C@@H](C=O)c1ccc(Cl)cc1Br.Clc1cccc([Mg]Br)c1>>CC(C)(C)OC(=O)N[C@H](c1ccc(Cl)cc1Br)[C@H](O)c1cccc(Cl)c1,,C1CCOC1,,,,test
US04812164,C#CCO.CC(C)OC(=O)c1cc(-n2c(Cl)nc(C(F)(F)C(F)(F)F)cc2=O)c(F)cc1Cl>>C#CCOc1nc(C(F)(F)C(F)(F)F)cc(=O)n1-c1cc(C(=O)OC(C)C)c(Cl)cc1F,,c1ccncc1,,,,test
US04603198,Cc1[nH]cnc1CCl.O=C1c2ccccc2C(=O)N1O>>Cc1[nH]cnc1CON1C(=O)c2ccccc2C1=O,,CCO,,Cl,[Na],test
US20040072873A1,CI.COc1cc(-c2ccc(N3C[C@H](CNC(C)=O)OC3=O)cc2)ccn1>>CC(=O)NC[C@H]1CN(c2ccc(C3CCN(C)C(=O)C3)cc2)C(=O)O1,,ClCCl,,C1CCOC1,O=C([O-])[O-].[K+].[K+],test
US20100016279A1,C[C@H](c1ccc(F)cc1)N1CCNCC1.FC(F)c1nnc2ccc(Cl)nn12>>C[C@H](c1ccc(F)cc1)N1CCN(c2ccc3nnc(C(F)F)n3n2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20120316165A1,Cc1cc([C@@H]2CN(C(=O)OC(C)(C)C)CCO2)ccc1NC(=O)Nc1ccc(Cl)nc1>>Cc1cc([C@@H]2CNCCO2)ccc1NC(=O)Nc1ccc(Cl)nc1,,CC#N,O,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20090215767A1,COc1ccc(-c2coc3cc(O)ccc3c2=O)cc1OC.ClCC1CO1>>COc1ccc(-c2coc3cc(OCC4CO4)ccc3c2=O)cc1OC,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20080188529A1,CCC[C@H](N[C@@H](c1ccc(Br)cc1)C(F)(F)F)C(=O)NC1(C#N)CC1.CS(=O)(=O)c1ccc(B(O)O)cc1>>CCC[C@H](N)C(=O)N([C@@H](c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1)C(F)(F)F)C1(C#N)CC1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20040266738A1,CC(C)OC(=O)NNc1ccc(Oc2cccc(C(F)(F)F)c2)cc1>>CC(C)OC(=O)N=Nc1ccc(Oc2cccc(C(F)(F)F)c2)cc1,,ClCCl,,[Na+].[O-]Cl,,test
US20130190338A1,NCCN1CCCC1.O=C(O)c1cccc(CSc2ccc(Cl)cc2NS(=O)(=O)c2ccc(Cl)c(C(F)(F)F)c2)c1>>O=C(NCCN1CCCC1)c1cccc(CSc2ccc(Cl)cc2NS(=O)(=O)c2ccc(Cl)c(C(F)(F)F)c2)c1,CN(C)c1ccncc1,CN(C)C=O,,ClCCCl,,test
US20090118292A1,CS(=O)(=O)Nc1cc(C#N)cc(C(=O)CBr)c1.Nc1ccc(Cl)nn1>>CS(=O)(=O)Nc1cc(C#N)cc(-c2cn3nc(Cl)ccc3n2)c1,,CCO,,,,test
US20040024034A1,CCOC(=O)C(C)(C)Oc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1C>>Cc1cc(OCCc2nc(-c3ccccc3)oc2C)ccc1OC(C)(C)C(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20080315754A1,Brc1ccc2c(-c3ccccc3)c(-c3ccccc3)oc2c1.COB(OC)OC>>OB(O)c1ccc2c(-c3ccccc3)c(-c3ccccc3)oc2c1,,C1CCOC1,CCCCCC,Cl,[Li]CCCC,test
US20110263598A1,CC1(C)OB(/C=C/c2cccnc2)OC1(C)C.Ic1n[nH]c2ccccc12.O=C1Nc2ccccc2C12CC2>>O=C1Nc2ccccc2[C@]12C[C@H]2c1ccc2c(/C=C/c3cccnc3)n[nH]c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,CCOC(C)=O,,test
US20100136142A1,CCOc1nccc2c1C(c1ccc(C#N)cc1OC)C(C(=O)O)=C(C(F)(F)F)N2.N>>CCOc1nccc2c1C(c1ccc(C#N)cc1OC)C(C(N)=O)=C(C(F)(F)F)N2,,CCOC(C)=O,,O=C(n1ccnc1)n1ccnc1,,test
US20060166983A1,CCOC(=O)Cn1ccc2cc(OCCc3nc(-c4ccc(C(F)(F)F)cc4)oc3C)ccc21>>Cc1oc(-c2ccc(C(F)(F)F)cc2)nc1CCOc1ccc2c(ccn2CC(=O)O)c1,,C1CCOC1,CCOCC,Cl,[Na+].[OH-],test
US20050215572A1,CSc1nc2c(c(Nc3ccc(C(C)(C)C)cc3)n1)CCN(c1ncccc1Cl)C2.O=C(OO)c1cccc(Cl)c1>>COc1nc2c(c(Nc3ccc(C(C)(C)C)cc3)n1)CCN(c1ncccc1Cl)C2,,CCO,,C[O-].[Na+],,test
US20080234261A1,CC(=O)Nc1cccc(Oc2cc(Nc3ccc4c(c3)CN(C(=O)OC(C)(C)C)CC4)c([N+](=O)[O-])cn2)c1>>CC(=O)Nc1cccc(Oc2cc(Nc3ccc4c(c3)CN(C(=O)OC(C)(C)C)CC4)c(N)cn2)c1,[Pd],CO,,[H][H],,test
US20090247474A1,C[C@H]1C[C@H](OC(=O)c2ccccc2)CN1C(=O)OC(C)(C)C>>C[C@H]1C[C@H](O)CN1C(=O)OC(C)(C)C,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20080214616A1,COC(=O)[C@@H](Cc1ccccc1F)N(Cc1ccccc1)Cc1ccccc1>>OC[C@@H](Cc1ccccc1F)N(Cc1ccccc1)Cc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070129345A1,COC(=O)Cl.Cc1cc(N)cnc1N1CCC2(CC1)CCN([C@@H]1CC[C@H](O)CC1)C2=O>>COC(=O)Nc1cnc(N2CCC3(CC2)CCN([C@@H]2CC[C@H](O)CC2)C3=O)c(C)c1,,CC#N,CO,CCN(C(C)C)C(C)C,,test
US05015656,COC(=O)c1csc(C)c1O.COS(=O)(=O)OC>>COC(=O)c1csc(C)c1OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100160369A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCN(CC)CC.NC(CO)COc1cc(Cl)c(-c2nnc(-c3cn4cc(C(F)(F)F)cc(Cl)c4n3)s2)cc1F>>CC(C)(C)OC(=O)NC(CO)COc1cc(Cl)c(-c2nnc(C3=CC4C=C(C(F)(F)F)C=C(Cl)C4=N3)s2)cc1F,,C1CCOC1,,,,test
US20090048320A1,O=C1CC(c2cccc(C#Cc3ccc(OC(F)F)cc3)c2)C1>>OC1CC(c2cccc(C#Cc3ccc(OC(F)F)cc3)c2)C1,,CO,,O,[BH4-].[Na+],test
US03989704,CNC(=O)c1ccccc1C(O)c1ccccc1>>O=C1OC(c2ccccc2)c2ccccc21,,Clc1ccccc1Cl,,,,test
US20120122843A1,OC(CNCc1ccc(Cl)nc1Cl)C1CC(F)(F)C1>>FC1(F)CC(C2CNCc3ccc(Cl)nc3O2)C1,,C1CCOC1,,[H-].[Na+],,test
US06169107A,CCOC(=O)c1cc2cc(NC(=O)c3ccccc3)ccc2n1C.Cl.N=C(N)N>>CNC(N)=NC(=O)c1cc2cc(NC(=O)c3ccccc3)ccc2[nH]1.Cl,,CO,,C[O-].[Na+],,test
US20120142705A1,CC(C)CC(C(=O)O)N1C(=O)C(=O)c2cc(Br)ccc21.Nc1nccs1>>CC(C)CC(C(=O)Nc1nccs1)N1C(=O)C(=O)c2cc(Br)ccc21,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20110152240A1,Cc1cc(NC2CC2)n2nc(C)c(C=O)c2n1.O=C1CSC(=O)N1>>Cc1cc(NC2CC2)n2nc(C)c(C=C3SC(=O)NC3=O)c2n1,,CN(C)C=O,,C1CCNCC1,,test
US20120258948A1,COc1ccc(COc2ccc(-c3ccn(CC[C@](C)(C(=O)NOC4CCCCO4)S(C)(=O)=O)c(=O)c3)cc2)cn1>>COc1ccc(COc2ccc(-c3ccn(CC[C@](C)(C(=O)NO)S(C)(=O)=O)c(=O)c3)cc2)cn1,,CC(C)O,,Cl,,test
US20060276508A1,COc1cc(OCC#N)cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)c1.OO>>COc1cc(OCC(N)=O)cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130303507A1,CO[C@H]1C[C@@H](NC(=O)OCc2ccccc2)CC[C@@H]1N=[N+]=[N-]>>CO[C@H]1C[C@@H](NC(=O)OCc2ccccc2)CC[C@@H]1N,[Zn],CC(=O)O,CO,,,test
US20060025423A1,COc1ncc(C)nc1N.O=S(=O)(Cl)c1cccc(Cl)c1Cl>>COc1ncc(C)nc1NS(=O)(=O)c1cccc(Cl)c1Cl,,c1ccncc1,,,,test
US20160168130A1,CCOC(=O)CC(=O)C(=O)OCC.NNCc1ccccc1F>>CCOC(=O)c1cc(O)n(Cc2ccccc2F)n1,,C1COCCO1,,[Na],,test
US20090131467A1,NN.O=C(Cc1cccc(C(F)(F)F)c1)c1c(O)c2cccnc2n(-c2cccc(OC(F)(F)F)c2)c1=O>>O=c1c2c(Cc3cccc(C(F)(F)F)c3)n[nH]c2c2cccnc2n1-c1cccc(OC(F)(F)F)c1,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US20120208817A1,CCOc1cc(C=O)cc([N+](=O)[O-])c1O.CN(C)c1ccc(C(=O)Cc2ccccc2)cc1.NC(N)=O>>CCOc1cc(C2NC(=O)NC(c3ccc(N(C)C)cc3)=C2c2ccccc2)cc([N+](=O)[O-])c1O,,CCO,,Cl,,test
US20120245144A1,Cc1nc(-c2cn3c(n2)-c2cc(S(=O)C4CCN(C(C)C)CC4)c(F)cc2OCC3)n(C(C)C)n1.O=C(OO)c1cccc(Cl)c1>>Cc1nc(-c2cn3c(n2)-c2cc(S(=O)(=O)C4CCN(C(C)C)CC4)c(F)cc2OCC3)n(C(C)C)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04115575,CC(C)N1CC(CO)OC1c1ccccc1.Cc1cnc(Cl)c(N2CCOCC2)n1>>Cc1cnc(OCC(O)CNC(C)C)c(N2CCOCC2)n1,,CN(C)P(=O)(N(C)C)N(C)C,,[H-].[Na+],,test
US20140274960A1,COC(=O)/C=C/c1cc(Cl)c(F)cc1-n1cnnn1>>O=C(O)/C=C/c1cc(Cl)c(F)cc1-n1cnnn1,,C1CCOC1,CO,[Na+].[OH-],,test
US20040254241A1,C=CC(=O)OC.CO.COCOc1ccc(C=O)cc1>>COCOc1ccc(/C=C(\COC)C(=O)O)cc1,,C1CCOC1,O,[H-].[Na+],,test
US04214004,Cc1cccc(-c2ccccc2F)c1.O=C1CCC(=O)N1Br>>Fc1ccccc1-c1cccc(CBr)c1,,ClC(Cl)(Cl)Cl,,,,test
US20120264734A1,COC(=O)c1c(C)c(N)cc(Br)c1F.O=C1CCOCC1>>COC(=O)c1c(C)c(NC2CCOCC2)cc(Br)c1F,,ClCCCl,O,CC(=O)O,O=C([O-])O.[Na+],test
US20090312382A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccccc1NC(=O)CNCC(O)c1cccc(Br)c1>>Cc1ccccc1NC(=O)CN(CC(O)c1cccc(Br)c1)C(=O)OC(C)(C)C,CN(C)c1ccncc1,C1CCOC1,,CCOC(C)=O,O=C([O-])O.[Na+],test
US04910318,CN.Cn1c2c(c3ccccc31)SCCC2C=O>>CN=CC1CCSc2c1n(C)c1ccccc21,,c1ccccc1,,,,test
US20030216394A1,Cn1nc(Cl)c(C(=O)n2cccn2)c1Cl.N#CCn1ccc(-c2c(F)cccc2F)n1>>Cn1nc(Cl)c(C(O)=C(C#N)n2ccc(-c3c(F)cccc3F)n2)c1Cl,,C1CCOC1,,O,[H-].[Na+],test
US20050054683A1,CC(=O)OC(C)=O.NC[C@H]1CN(c2ccc(C3CN(C(=O)OCc4ccccc4)C3)c(F)c2)C(=O)O1>>CC(=O)NC[C@H]1CN(c2ccc(C3CN(C(=O)OCc4ccccc4)C3)c(F)c2)C(=O)O1,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20150183802A1,Cc1nn(-c2cnc(OCC(C)C)c(Cl)c2)c2cc(F)c(C#N)cc12.N#Cc1cc2c(cc1F)NC(=O)C1(CC1)O2>>CC(C)COc1ncc(N2C(=O)C3(CC3)Oc3cc(C#N)c(F)cc32)cc1Cl,[Cu]I,CC#N,,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US20160244429A1,COc1ccc2[nH]cc(CCCCOS(=O)(=O)c3ccc(C)cc3)c2c1.O=c1c2ccoc2ccn1-c1ccc(N2CCNCC2)cc1>>COc1ccc2[nH]cc(CCCCN3CCN(c4ccc(-n5ccc6occc6c5=O)cc4)CC3)c2c1,,CC#N,,[I-].[K+],,test
US07037919B1,C1=CCC=C1.CC(C)(C=O)CO.Nc1ccc([N+](=O)[O-])cc1>>CC(C)(CO)C1Nc2ccc([N+](=O)[O-])cc2C2C=CCC21,,CC#N,,O=C(O)C(F)(F)F,,test
US20160237090A1,C[C@H]1Cn2ncc(N3CC(NC(=O)OC(C)(C)C)CC3=O)c2CN1.Nc1cc(F)c(F)c(F)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>C[C@H]1Cn2ncc(N3CC(NC(=O)OC(C)(C)C)CC3=O)c2CN1C(=O)Nc1cc(F)c(F)c(F)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070049578A1,CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)C(C(=O)O)C1.N>>CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)C(C(N)=O)C1,,C1CCOC1,CN(C)C=O,CC(C)COC(=O)Cl,CCN(CC)CC,test
US04824848,CCCCn1c(=O)cc(Cl)[nH]c1=O.COc1ccc(CCl)cc1>>CCCCn1c(=O)cc(Cl)n(Cc2ccc(OC)cc2)c1=O,,CN(C)C=O,,[I-].[K+],,test
US20060160770A1,CCCCCCCCCCO.C[Si](C)(C)C#C/C=C\c1ccccn1>>CCCCCCCCCCOCc1ccc2ccccn12,,Cc1ccccc1,,[Cs+].[F-],,test
US20070054898A1,CC(C)N(CCCl)C(C)C.CN(C)C=O.Cc1ccc2[nH]c(=O)c(C#N)c(N3CCN(C(=O)c4cccs4)CC3)c2c1>>Cc1ccc2c(c1)c(N1CCN(C(=O)c3cccs3)CC1)c(C#N)c(=O)n2CCN(C)C,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US07109229B2,CC(C)(C)[Si](C)(C)Cl.OCCCc1cccc2cc[nH]c12>>CC(C)(C)[Si](C)(C)OCCCc1cccc2cc[nH]c12,,ClCCl,,c1c[nH]cn1,,test
US20110065708A1,BrCCBr.COC(=O)Cc1ccc2ncccc2c1>>COC(=O)C1(c2ccc3ncccc3c2)CC1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20040082639A1,O=C1CCc2ccccc21.S=C=Nc1ccccc1>>O=C1c2ccccc2CC1C(=S)Nc1ccccc1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20140018344A1,Brc1cnc2cc[nH]c2c1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)n2ccc3ncc(Br)cc32)cc1,,CN(C)C=O,ClCCl,[H-].[Na+],,test
US20150175599A1,CO.COc1cc2cc(C)[nH]c2cc1F.O=C(Cl)C(=O)Cl>>COC(=O)C(=O)c1c(C)[nH]c2cc(F)c(OC)cc12,,ClCCl,,,,test
US04973599,Cl.Cn1ccnc1Sc1c(Cl)cccc1Cl>>Cl.Cn1ccnc1Sc1c(Cl)cccc1Cl,,CCOCC,ClCCl,,,test
US20110086834A1,Nc1cc(I)ccc1CN1CCOCC1.Nc1ncc(Cl)c(Cl)n1>>Nc1ncc(Cl)c(Nc2cc(I)ccc2CN2CCOCC2)n1,,C1COCCO1,,Cl,[Na+].[OH-],test
US06204264B1,CCCCCCCCCCCCCCCCCCn1c(C(=O)NCCCN(C)C)nc2ccccc21.Cl>>CCCCCCCCCCCCCCCCCCn1c(C(=O)NCCCN(C)C)nc2ccccc21.Cl,,CCOC(C)=O,,CCO,,test
US20120190635A1,CC(=O)OC1C(F)OC(C)CC1N(C)C.OC1CCCCCCCCCCCC1>>CC(=O)OC1C(OC2CCCCCCCCCCCC2)OC(C)CC1N(C)C,,CCOC(C)=O,,CCOCC,FB(F)F,test
US20040132727A1,COc1cc2ncnc(Oc3ccc(N)cc3)c2cc1OC.Cc1ccc(C(C)O)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2ncnc(Oc3ccc(NC(=O)OC(C)c4ccc(C)cc4)cc3)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20040152690A1,Clc1cccc(Cl)c1CBr.FC(F)(F)c1ccc2nc(N3CCNCC3)[nH]c2c1>>FC(F)(F)c1ccc2nc(N3CCN(Cc4c(Cl)cccc4Cl)CC3)[nH]c2c1,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US04287340,N#Cc1ccc2nc3c(c(=O)n2c1)CSC3.[N-]=[N+]=[N-]>>O=c1c2c(nc3ccc(-c4nnn[nH]4)cn13)CSC2,,CN(C)C=O,,[Cl-].[NH4+],,test
US20110212053A1,NCc1ccccc1.O=C(Cl)c1cncc(Br)c1>>O=C(NCc1ccccc1)c1cncc(Br)c1,,ClCCl,O,CCN(CC)CC,,test
US20140323475A1,C1N2CN3CN1CN(C2)C3.CCOC(=O)c1ccnc2[nH]ccc12.O>>CCOC(=O)c1ccnc2[nH]cc(C=O)c12,,CC(=O)O,,,,test
US20080176904A1,CCCc1c(OCc2cccc([Sn](C)(C)C)c2)ccc2c1ccn2CC(C)(C)C.COC(=O)c1cccc(Br)n1>>CCCc1c(OCc2cccc(-c3cccc(C(=O)O)n3)c2)ccc2c1ccn2CC(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20100016306A1,CCOC(=O)C(C)(C)N1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCN(C(C)(C)CO)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110190353A1,Cn1nnnc1C(=O)c1cccc(OC(F)(F)F)c1.NO>>Cn1nnnc1C(=NO)c1cccc(OC(F)(F)F)c1,,CCOC(C)=O,c1ccncc1,Cl,,test
US20030130340A1,CC(C)Br.Oc1cccc(-c2ccc3c(-c4cccnc4)csc3c2)c1>>CC(C)Oc1cccc(-c2ccc3c(-c4cccnc4)csc3c2)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20110306588A1,COC(=O)Cl.c1ccc2nc(N3CC(Oc4nccnc4C4CCNCC4)C3)ccc2c1>>COC(=O)N1CCC(c2nccnc2OC2CN(c3ccc4ccccc4n3)C2)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20090068242A1,CC(C)(C)c1cccc(O)c1.O=C(Oc1ccc([N+](=O)[O-])cc1)Oc1ccc([N+](=O)[O-])cc1>>CC(C)(C)c1cccc(OC(=O)Oc2ccc([N+](=O)[O-])cc2)c1,CN(C)c1ccncc1,CCCCCC,CCOC(C)=O,ClCCl,,test
US20100305093A1,CS(=O)(=O)c1ccc(C(=O)N2CCOc3ccc(-c4ccc(N)c(N)c4)cc3C2)cc1.S=C(n1ccnc1)n1ccnc1>>CS(=O)(=O)c1ccc(C(=O)N2CCOc3ccc(-c4ccc5[nH]c(=S)[nH]c5c4)cc3C2)cc1,,C1CCOC1,,,,test
US20030056669A1,CN(C)C.Cc1cccc(CBr)c1>>Cc1cccc(C[N+](C)(C)C)c1.[Br-],,CCOCC,,CO,,test
US05585394,CN(C)c1ccc(N)cc1>>CN(C)C1CCC(N)CC1,[Pd],CC(=O)O,,,,test
US20120245168A1,CC1(C)OC(O)C(=O)c2sc(=S)sc21.Nc1ccccc1N>>CC(C)(O)c1sc(=S)sc1-c1cnc2ccccc2n1,,ClCCl,,,,test
US05539112,CC(C)(C)C(=O)Nc1ccc(-c2cc(=O)c3c(NC(=O)C(C)(C)C)c(F)c(Br)c(F)c3o2)cc1F.CN1CCNCC1>>CN1CCN(c2c(F)c(NC(=O)C(C)(C)C)c3c(=O)cc(-c4ccc(NC(=O)C(C)(C)C)c(F)c4)oc3c2F)CC1,,CS(C)=O,,O,,test
US20030232846A1,C[C@@H](C(=O)OC(C)(C)C)N1C(=O)c2ccccc2C1=O>>C[C@@H](C(=O)OC(C)(C)C)N1C(=O)c2ccccc2C1O,,C1CCOC1,CO,[BH4-].[Na+],,test
US20130115190A1,CCOC(=O)[C@@]12C[C@H]1C=CCCC(C)C[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N1C[C@H](Oc3ncc(OC)c4c(Cl)cccc34)C[C@H]1C(=O)N2>>COc1cnc(O[C@@H]2C[C@H]3C(=O)N[C@]4(C(=O)O)C[C@H]4C=CCCC(C)C[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N3C2)c2cccc(Cl)c12,,C1CCOC1,O,CO,[Li+].[OH-],test
US20040235892A1,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.Cc1cccc(N=C=O)c1>>Cc1cccc(NC(=O)Nc2ccc(B3OC(C)(C)C(C)(C)O3)cc2)c1,,C1CCOC1,,,,test
US07250063B2,CN.COCCn1nc(Br)c([N+](=O)[O-])c1Br>>CNc1c([N+](=O)[O-])c(Br)nn1CCOC,,CCO,,,,test
US06288061B1,CN1CCOC2(CCN(c3ccc(C#N)cc3)CC2)C1>>CN1CCOC2(CCN(c3ccc(CN)cc3)CC2)C1,,C1CCOC1,,[H-].[Na+],,test
US04448969,C=O.CC1(C)NC(=O)C(C)(C)N1>>CN1C(C)(C)NC(=O)C1(C)C,,O,,O=CO,,test
US20130281434A1,COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(-c4ccc5[nH]ncc5c4)c3)sc2c1-c1ccc(Cl)cc1>>Cc1cc2nc(-c3ccnc(-c4ccc5[nH]ncc5c4)c3)sc2c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O,,CO,,O,,test
US20160222005A1,BrCc1ccccc1.COC(=O)c1cc(C=O)ccc1O>>COC(=O)c1cc(C=O)ccc1OCc1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140259230A1,COB(OC)OC.COCOCc1cc(Cl)ccc1Br>>OB1OCc2cc(Cl)ccc21,,C1CCOC1,CCOC(C)=O,CCCCCC,[Li]CCCC,test
US20070208010A1,CC(C)(C)OC(=O)N[C@@H](CC(=O)NN)Cc1cc(F)c(F)cc1F.COC1=NCCc2cnc(C(F)(F)F)nc21>>CC(C)(C)OC(=O)N[C@@H](CC(=O)NNC1=NCCc2cnc(C(F)(F)F)nc21)Cc1cc(F)c(F)cc1F,,CCOCC,,CO,,test
US20040157849A1,COC(=O)n1ncc2c(N)cccc21.NCc1ccc(N2C3CCCC2CC3)c(C(F)(F)F)c1.O=C(Cl)Cl>>COC(=O)n1ncc2c(NC(=O)NCc3ccc(N4C5CCCC4CC5)c(C(F)(F)F)c3)cccc21,,C1CCOC1,Cc1ccccc1,,,test
US04183948,CC1(C)[C@@H](C=C(Cl)C(F)(F)F)[C@@H]1C(=O)Cl.N#CC(O)c1cccc(Oc2ccccc2)c1>>CC1(C)[C@H](C=C(Cl)C(F)(F)F)[C@@H]1C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1,,O,,c1ccncc1,,test
US20050245592A1,CCOc1cc(CN=[N+]=[N-])c(C#N)cc1C(=O)OC(C)(C)C>>CCOc1cc(CN=[N+]=[N-])c(C#N)cc1C(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100130474A1,N#CC(F)C(=O)c1cnc2ccccc2c1.NN>>Nc1[nH]nc(-c2cnc3ccccc3c2)c1F,,CCO,,O,,test
US20160052888A1,CC(=O)[C@@H]1CCc2cc([C@H]3CC[C@]4(COC(=O)N4)C3)ccc2C1.O=C(OO)c1cccc(Cl)c1>>CC(=O)O[C@@H]1CCc2cc([C@H]3CC[C@]4(COC(=O)N4)C3)ccc2C1,,ClCCl,,,,test
US20120040949A1,CN1CCN(c2cnc([N+](=O)[O-])cn2)CC1>>CN1CCN(c2cnc(N)cn2)CC1,[Pd],CO,,,,test
US05780480,CCOC(=O)C1(c2ccccn2)CCNCC1>>O=C(O)C1(c2ccccn2)CCNCC1,,C1CCOC1,,O,[Li+].[OH-],test
US20110190257A1,COc1cc(F)c(C=O)c(Nc2ccc(I)cc2F)c1[N+](=O)[O-].NN>>COc1cc2[nH]ncc2c(Nc2ccc(I)cc2F)c1[N+](=O)[O-],,COCCOC,,O,,test
US20080004289A1,O=C(c1ccccc1)c1cccc(Br)c1>>OC(c1ccccc1)c1cccc(Br)c1,,CO,O,[BH4-].[Na+],,test
US20060160864A1,CCCCOCCOc1ccc(-c2cnc(N3CCC(C)C3)c(/C=C(\C)C(=O)Nc3ccc(SCc4nncn4CCC)cc3)c2)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2cnc(N3CCC(C)C3)c(/C=C(\C)C(=O)Nc3ccc(S(=O)Cc4nncn4CCC)cc3)c2)cc1,,ClCCl,,,,test
US04242519,COC(=O)C(C)(SC)c1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1>>COC(=O)C(C)(SC)c1ccc(N)c(Cl)c1,,CO,,NN,O,test
US20070191364A1,COc1ccc(N(C2CCCCC2)C2CCN(C(=O)OC(C)(C)C)CC2)cc1>>COc1ccc(N(C2CCCCC2)C2CCNCC2)cc1,,C1COCCO1,Cl,,,test
US20110218193A1,CCOC(=O)CCc1ccc(NC(=O)c2cccnc2Cl)cc1.COCCl>>CCOC(=O)CCc1ccc(N(COC)C(=O)c2cccnc2Cl)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20100056518A1,CC(C)(C)[Si](C)(C)Cl.O[C@@H]1CCC[C@H](O)CCC1>>CC(C)(C)[Si](C)(C)O[C@@H]1CCC[C@H](O)CCC1,CN(C)c1ccncc1,C1CCOC1,,c1c[nH]cn1,,test
US04294960,O=CNc1nc(C(=NOCCCl)C(=O)NC2C(=O)N3C(C(=O)O)=CCS[C@H]23)cs1>>Nc1nc(C(=NOCCCl)C(=O)NC2C(=O)N3C(C(=O)O)=CCS[C@H]23)cs1,,C1CCOC1,,CO,Cl,test
US05512183,C=C(C)CC(C)(C)C.C=C(C)P(=O)(O)O>>C=C(C)CC(C)(C)C.C=C(C)P(=O)(O)O,,COCCOC,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20080255155A1,CC(=O)Nc1ccc(Oc2ccnc(Cl)n2)c(F)c1.Nc1ccccc1>>CC(=O)Nc1ccc(Oc2ccnc(Nc3ccccc3)n2)c(F)c1,,C1COCCO1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04464300,Fc1ccccc1C1CCC(=S)Nc2ccc(Cl)cc21.NN>>NNC1CCC(c2ccccc2F)c2cc(Cl)ccc2N1,,C1CCOC1,,O,,test
US20150087646A1,Cc1cccc(C)c1C(=O)O.O=C(NCO)C(F)(F)F>>Cc1ccc(CNC(=O)C(F)(F)F)c(C)c1C(=O)O,,O=S(=O)(O)O,,,,test
US20050080124A1,COc1ccc(N)cc1-c1c(Br)c(C(F)(F)F)nn1C.O=C=Nc1ccc(F)cc1>>COc1ccc(NC(=O)Nc2ccc(F)cc2)cc1-c1c(Br)c(C(F)(F)F)nn1C,,ClCCl,,,,test
US20130079346A1,COC(=O)c1cc(C(N)=S)ccc1-c1ccccc1[N+](=O)[O-].O=C(CBr)c1cccc(Cl)c1>>O=C(O)c1cc(-c2nc(-c3cccc(Cl)c3)cs2)ccc1-c1ccccc1[N+](=O)[O-],,O,,,,test
US20100305140A1,C=C(C)CBr.CC(C)(C)c1nc2cc(C(=O)N3CCC(O)CC3)ccc2n1CC1CCC(F)(F)CC1>>C=C(C)COC1CCN(C(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCC(F)(F)CC2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20100113439A1,CC[Si](CC)(CC)OS(=O)(=O)C(F)(F)F.NC(=O)c1nc[nH]n1>>CC[Si](CC)(CC)NC(=O)c1nc[nH]n1,,ClCCCl,ClCCl,Cc1cccc(C)n1,,test
US20080119538A1,CC(=O)N(C[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@H](Cl)C[C@H]1O)c1cc(Cl)cc(Cl)c1>>O=C(O)CCC/C=C\C[C@H]1[C@H](Cl)C[C@@H](O)[C@@H]1CNc1cc(Cl)cc(Cl)c1,,C1CCOC1,,[Li+].[OH-],,test
US20070037836A1,CN(C)c1nc(N[C@@H]2CC[C@H](N)CC2)nc2ccccc12.O=S(=O)(Cl)c1ccc(Br)cc1OC(F)(F)F>>CN(C)c1nc(N[C@@H]2CC[C@H](NS(=O)(=O)c3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20050113340A1,NC(=O)Cc1cccc(Cl)c1Cl.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>NC(=S)Cc1cccc(Cl)c1Cl,,Cc1ccccc1,,,,test
US20030050313A1,O=[N+]([O-])c1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCOCC1>>Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCOCC1,[Ni],C1CCOC1,,,,test
US20140329825A1,BrCc1ccccc1.CC#N.N#Cc1ccc(Cl)nn1>>N#Cc1ccc(NCc2ccccc2)nn1,,CCOC(C)=O,O,CCN(C(C)C)C(C)C,,test
US05977355,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc2c(c1)NC(=O)C(N)CC2c1ccccc1>>Cc1ccc2c(c1)NC(=O)C(NC(=O)OC(C)(C)C)CC2c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20100068771A1,NC[C@@H](O)c1ccc(F)cc1>>NC[C@H](O)c1ccc(F)cc1,,CCO,,,,test
US20100016279A1,OCCBr.Oc1ccc(N2CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)cc1>>FC(F)(F)c1nnc2ccc(N3CCN(c4ccc(OCCBr)cc4)CC3)nn12,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06362177B1,CC(C)(C)OC(=O)Nc1cc(F)c(F)cc1C(=O)NCC(=O)NCC1CCNCC1.CCOc1ccc(Br)cc1C=O>>CCOc1ccc(Br)cc1CN1CCC(CNC(=O)CNC(=O)c2cc(F)c(F)cc2N)CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20070208056A1,COC(=O)c1ccccc1CNC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCc1ccccc1C(=O)O,,C1CCOC1,,Cl,[Na+].[OH-],test
US20060058361A1,CC[Mg]Br.COC(OC)c1ccc(C=O)cc1F>>CCC(O)c1ccc(C(OC)OC)c(F)c1,,CCOCC,O,,,test
US20150119254A1,C#CCCCCCCC=O.OCCO>>C#CCCCCCCC1OCCO1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20040152702A1,COCCN(C)Cc1ccc(C(=O)Cl)cc1.COc1ccc(-c2ccccc2)c2oc(N)nc12>>COCCN(C)Cc1ccc(C(=O)Nc2nc3c(OC)ccc(-c4ccccc4)c3o2)cc1,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20030232863A1,CC(C)(O)C[C@H]1COC(=O)N1.CCN(CC)S(F)(F)F>>CC(C)(F)C[C@H]1COC(=O)N1,,ClCCl,,O=C([O-])O.[Na+],,test
US20030166644A1,CC1(C)CC(=O)OC(=O)C1.Nc1ccc(O)cc1>>CC1(C)CC(=O)N(c2ccc(O)cc2)C(=O)C1,,CCO,,C,,test
US20090054435A1,CCC(Br)C(=O)OC.COc1ccc(C(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c(O)c1>>CCC(Oc1cc(OC)ccc1C(=O)c1ccc(OCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20030087902A1,CCOC(=O)c1c(-c2ccc(C(C)(C)C)cc2)c2cc(N)ccc2n1Cc1cccc(OC)c1.O=C(Cl)C1CC1>>COC(=O)c1c(-c2ccc(C(C)(C)C)cc2)c2cc(NC(=O)C3CC3)ccc2n1Cc1cccc(OC)c1,,ClCCl,,CCN(CC)CC,CN(C)c1ccccn1,test
US20110275610A1,CC(C)(C)OC(=O)C1CN(Cc2ccc(/C(N)=N/OC(=O)c3cc(-c4ccccc4)c(C(F)(F)F)s3)cc2)C1>>CC(C)(C)OC(=O)C1CN(Cc2ccc(-c3noc(-c4cc(-c5ccccc5)c(C(F)(F)F)s4)n3)cc2)C1,,CC#N,,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20050245519A1,CC(C)(C)OC(=O)N1CCO[C@H](CO)C1.CCOc1ccccc1O>>CCOc1ccccc1OC[C@@H]1CN(C(=O)OC(C)(C)C)CCO1,,COCCOC,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05681833,CCN(CC)CC.Nc1cccc([N+](=O)[O-])c1.S=C(Cl)Cl>>NC(=S)Nc1cccc([N+](=O)[O-])c1,,C1CCOC1,,,,test
US03966801,CCOC(=O)C(O)CCc1ccc(C2CCCCC2)c(Br)c1.FC(F)(F)I>>CCOC(=O)C(O)CCc1ccc(C2CCCCC2)c(C(F)(F)F)c1,[Cu],CN(C)C=O,,,,test
US05264437,ClCc1ccncc1.O=c1[nH]c(=O)n(-c2cccc([N+](=O)[O-])c2)c2ncccc12>>O=c1c2cccnc2n(-c2cccc([N+](=O)[O-])c2)c(=O)n1Cc1ccncc1,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US06166064,CC(=O)Cl.Fc1ccc2c(c1)CCN2>>CC(=O)C1Cc2cc(F)ccc2N1,,ClCCl,O,CCN(CC)CC,,test
US05135955,CCCCC(CC)COc1ccc(C=C(C#N)c2ccccc2)cc1>>CCCCC(CC)COc1ccc(CC(CN)c2ccccc2)cc1,[Ni],C1CCOC1,,N,,test
US20150353553A1,CSc1nc(NC(C)C2CC(C)C2)c2c(ncn2Cc2ccc(C(F)(F)F)cc2)n1.O=S([O-])OO>>CC1CC(C(C)Nc2nc(S(C)(=O)=O)nc3ncn(Cc4ccc(C(F)(F)F)cc4)c23)C1,,O,,CO,,test
US20020198197A1,COc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(C#N)c2)cc1-n1cccc1C(C)(C)C>>COc1cc2c(cc1-n1cccc1C(C)(C)C)NC(=O)CC(c1cccc(C#N)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110142796A1,CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nc2)CC1>>c1cc2c3cnc(Nc4ccc(N5CCNCC5)cn4)nc3n(C3CCCC3)c2cn1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20090105134A1,[N-]=[N+]=NCCCCCCCCCCN1C(=O)c2ccccc2C1=O>>[N-]=[N+]=NCCCCCCCCCCN,,CCO,,NN,O,test
US20030207877A1,CC(C)[Si](OC(=CCl)c1ccccn1)(C(C)C)C(C)C>>O=C(CCl)c1ccccn1,,CC#N,,ClCCl,O=C([O-])O.[Na+],test
US20120208819A1,Fc1ccc2ocnc2c1.Nc1ncc(C(F)(F)F)cc1Br>>Nc1ncc(C(F)(F)F)cc1-c1nc2cc(F)ccc2o1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(=O)N(C)C,,CC(=O)[O-].[K+],,test
US20060154958A1,CC(C)(C)OC(=O)N[C@H]1C[C@@H](CN=[N+]=[N-])OC1=O>>CC(C)(C)OC(=O)NC1CC(O)CNC1=O,,CO,,,,test
US20010049371A1,CCOc1cc(C(CC(=O)O)N2C(=O)c3ccc(C(C)(C)C)cc3C2=O)ccc1OC.NO>>CCOc1cc(C(CC(=O)NO)N2C(=O)c3ccc(C(C)(C)C)cc3C2=O)ccc1OC,,C1CCOC1,,Cl,O=C(n1ccnc1)n1ccnc1,test
US05324743,CCCI.COc1cccc(OC)c1>>CCCc1c(OC)cccc1OC,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US04012413,CO.N#CCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2.O=C([O-])O>>COC(=O)Cc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2,,CCOCC,O,Cl,,test
US20070213361A1,CCc1nc2c(C)cc(C)nc2n1Cc1cccc(C(=O)c2ccc(CO[Si](C)(C)C(C)(C)C)cc2)c1>>CCc1nc2c(C)cc(C)nc2n1Cc1cccc(C(=O)c2ccc(CO)cc2)c1,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110015157A1,C=CC[Mg]Br.COC(=O)N(CCC(=O)c1ccccc1)c1cccc(Br)c1>>C=CCC1(c2ccccc2)CCN(c2cccc(Br)c2)C(=O)O1,,C1CCOC1,,,,test
US06057441,C=CC[Mg]Br.c1ccc2c(c1)Cc1ccccc1C1OC21>>C=CCC1c2ccccc2Cc2ccccc2C1O,,C1CCOC1,,,,test
US20050277661A1,CCCC[Sn](C=COCC)(CCCC)CCCC.CCOC(=O)c1ncc2c(ccn2Cc2ccc(F)cc2)c1OS(=O)(=O)C(F)(F)F>>CCO/C=C/c1c(C(=O)OCC)ncc2c1ccn2Cc1ccc(F)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,CCN(CC)CC,,test
US05525711,CC(=O)C=O.Nc1nc(=O)[nH]c(N)c1N>>Cc1cnc2c(N)nc(=O)[nH]c2n1,,O,,Cl,,test
US05852016,CN=C=O.COc1nc2cc(Cl)c(Cl)c(N(CCN)S(C)(=O)=O)c2nc1OC>>CNC(=O)NCCN(c1c(Cl)c(Cl)cc2nc(OC)c(OC)nc12)S(C)(=O)=O,,ClCCl,,,,test
US05688815,Cl.O=c1ccn(CCO)c(C(O)c2ccc([N+](=O)[O-])cc2)c1OCc1ccccc1>>Cl.O=c1ccn(CCO)c(C(O)c2ccc([N+](=O)[O-])cc2)c1O,,Cc1ccccc1,,,,test
US20130331349A1,COC(=O)c1c([C@@H]2C[C@H]2C(F)(F)F)noc1C1CC1>>OCc1c([C@@H]2C[C@H]2C(F)(F)F)noc1C1CC1,,C1CCOC1,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US06329547B1,CCOC(=O)C(=O)c1ccc(C)cc1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)/C=C(\C(=O)OCC)c1ccc(C)cc1,,C1CCOC1,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20100266714A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COC(=O)c1cc(Br)cc(-c2ccc(C)cn2)c1>>COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)cc(-c2ccc(C)cn2)c1,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20150336962A1,ClCC1CO1.O=C(Nc1c[nH]nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12>>O=C(Nc1cn(CC2CO2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110039843A1,Cc1cn[nH]c1.Fc1cnccc1-c1nc2cc(C(F)(F)F)ccc2o1>>Cc1cnn(-c2cnccc2-c2nc3cc(C(F)(F)F)ccc3o2)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140256710A1,Nc1ccc(F)cc1F.O=[N+]([O-])c1cnc(Cl)c(Br)c1>>O=[N+]([O-])c1cnc(Nc2ccc(F)cc2F)c(Br)c1,,CS(C)=O,,,,test
US20110152318A1,CC(NC(=O)c1coc(Cl)n1)c1cc(F)c(NS(C)(=O)=O)c(F)c1.CC1(C)OB(c2cc(C3CC3)cc(C3CC3)c2)OC1(C)C>>CC(NC(=O)c1coc(-c2cc(C3CC3)cc(C3CC3)c2)n1)c1cc(F)c(NS(C)(=O)=O)c(F)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140155427A1,COC(=O)c1cccc(C=O)c1.O=C1CCC(=O)N1Br>>COC(=O)c1cc(Br)cc(C=O)c1,,O=S(=O)(O)O,,,,test
US20140114068A1,Cc1cc2c(cc1C)C1(N)C(=O)c3ccccc3C1(O)O2.O=C(O)c1cccnc1>>Cc1cc2c(cc1C)C1(NC(=O)c3cccnc3)C(=O)c3ccccc3C1(O)O2,,CN(C)C=O,ClCCl,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20080255197A1,Cc1cccnc1CN(Cc1ncccc1C)C1CCNCC1.NS(N)(=O)=O>>Cc1cccnc1CN(Cc1ncccc1C)C1CCN(S(N)(=O)=O)CC1,,C1COCCO1,,,,test
US04609399,CCOC(=O)c1c(OC(C)C)cc(OC(C)C)nc1C(F)(F)F>>CC(C)Oc1cc(OC(C)C)c(C(=O)O)c(C(F)(F)F)n1,,CO,,[K+].[OH-],,test
US20140186875A1,CCCCCCCc1c[nH]c(CCC(=O)OCC)c1>>CCCCCCCc1c[nH]c(CC(CC)C(=O)O)c1,,[Na+],[OH-],CCOC(C)=O,Cl,test
US20010027196A1,CS(=O)c1nc(N)nc(-c2ccco2)c1C#N.NCc1ccccc1Cl>>N#Cc1c(NCc2ccccc2Cl)nc(N)nc1-c1ccco1,,COCCOC,,,,test
US20040087800A1,O=C1Nc2ccccc2C12CCCCNC2>>O=C1Nc2ccccc2C12CCCCNC2,[Pd],CC(=O)O,,Cl,,test
US20050176784A1,ClCc1cccnc1.N#CC(C#N)CCC(F)(F)F>>N#CC(C#N)(CCC(F)(F)F)Cc1cccnc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05859007,COC(=O)c1nn(C)c2ccccc12>>Cn1nc(CO)c2ccccc21,,CCCCCC,ClCCl,CC(C)C[AlH]CC(C)C,,test
US20050020581A1,O=CNc1cc(Cl)ccc1CO>>O=CNc1cc(Cl)ccc1C=O,,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20080051418A1,CCOC(=O)CCc1c[nH]nc1OCC.ClCc1ccc(Cl)cc1Cl>>CCOC(=O)CCc1cn(Cc2ccc(Cl)cc2Cl)nc1OCC,,CN(C)C=O,,O,[H-].[Na+],test
US20040127527A1,C=CC#N.O=C(NCC(=O)c1cccs1)c1ccc(F)cc1>>N#CCCc1nc(-c2ccc(F)cc2)oc1-c1cccs1,,CN(C)C=O,,[H-].[Na+],,test
US20100184786A1,COc1ccc(CN)cc1.O=S(=O)(Cl)c1cccc(Br)c1>>COc1ccc(CNS(=O)(=O)c2cccc(Br)c2)cc1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20040092728A1,I.Nc1ccc(C(=O)c2ccccc2)cc1>>O=C(c1ccccc1)c1ccc(I)cc1,,CCOCC,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20090312338A1,Cc1ccc(S(=O)(=O)n2ccc3nc(/C=C/c4ccccc4)cnc32)cc1.O>>Cc1ccc(S(=O)(=O)n2ccc3nc(C=O)cnc32)cc1,,O,,C1COCCO1,,test
US20090036450A1,CCOC(=O)CC(C(C)=O)C(C)=O.Cc1cccc(NN)c1>>Cc1cccc(-n2nc(C)c(CC(=O)O)c2C)c1,,CCO,,[Na+].[OH-],,test
US05952306,CC(C)(C)OC(=O)NCC(=O)NC[C@H](NS(=O)(=O)c1ccccc1)C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CC(C)(C)OC(=O)[C@H](CNC(=O)CN)NS(=O)(=O)c1ccccc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US05981533,COc1cccc(CN)c1.CSC(SC)=C(C#N)C#N>>COc1cccc(CNC(SC)=C(C#N)C#N)c1,,CCOC(C)=O,,,,test
US20110028445A1,COc1ccc2c(c1)C1CC(=O)NC2C1>>COc1ccc2c(c1)C1CCNC2C1,,C1CCOC1,,Cl,,test
US20110207771A1,CC(F)(CN)c1ccc(Cl)cc1Cl.Cn1cc(C(=O)Cl)c(C(F)F)n1>>Cn1cc(C(=O)NCC(C)(F)c2ccc(Cl)cc2Cl)c(C(F)F)n1,,ClCCl,,CCN(CC)CC,Cl,test
US20090286807A1,CC(C)[C@@H]1C[C@@H](C2C[N@@]2S(=O)(=O)c2ccccc2[N+](=O)[O-])OC1=O.COCOc1ccccc1N1CC(C)(C)NCC1=O>>COCOc1ccccc1N1CC(C)(C)N(C[C@H](NS(=O)(=O)c2ccccc2[N+](=O)[O-])[C@@H]2C[C@@H](C(C)C)C(=O)O2)CC1=O,,Cc1ccccc1,,,,test
US20140329807A1,CS(=O)(=O)Cl.N[C@@H]1CC[C@@H](Nc2ccc3ncc(-c4cccc(OC(F)(F)F)c4)n3n2)CC1>>CS(=O)(=O)N[C@@H]1CC[C@@H](Nc2ccc3ncc(-c4cccc(OC(F)(F)F)c4)n3n2)CC1,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
USRE028973,O=C(C(=O)N1CCC(O)(c2ccccc2)CC1)c1c[nH]c2ccccc12>>OC1(c2ccccc2)CCN(CCc2c[nH]c3ccccc23)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070185109A1,CCOC(=O)CC(=O)c1cccc(C)c1.O=Cc1ccccc1>>CCOC(=O)C(=Cc1ccccc1)C(=O)c1cccc(C)c1,,c1ccccc1,,C1CCNCC1,CC(=O)O,test
US20120157448A1,NC1=NC2(CO1)c1cc(Br)ccc1O[C@H]1CCN(C(=O)OCc3ccccc3)C[C@@H]12.OB(O)c1cccnc1F>>NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1O[C@H]1CCN(C(=O)OCc3ccccc3)C[C@@H]12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20090318385A1,CCC(=O)c1ccc(OC)n2nc(C(F)F)cc12.COC(=O)OC>>COC(=O)c1ccc(OC)n2nc(C(F)F)cc12,CO,,,[H-].[Na+],[Cl-].[NH4+],test
US04206309,C=COCCN1C(=O)NC(C)(C)C1=O.CC1CO1>>C=COCCN1C(=O)N(CC(C)O)C(C)(C)C1=O,,CN(C)C=O,,[Cl-].[Li+],,test
US04303655,CCOC(=O)Cc1csc(N)n1.CS(=O)(=O)Cl>>CCOC(=O)Cc1csc(NS(C)(=O)=O)n1,,ClCCl,,c1ccncc1,,test
US20120259123A1,CCCCC(C)(C)c1ccc(CNC(c2cccc(N(CC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n2)S(=O)(=O)c2ccco2)cc1>>CCCCC(C)(C)c1ccc(CNC(c2cccc(NCC(=O)O)n2)S(=O)(=O)c2ccco2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130331460A1,COc1cc(CC#C[Si](C)(C)C)cc(OC)c1>>C#CCc1cc(OC)cc(OC)c1,,C1CCOC1,CCOCC,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20110251186A1,CC(CO)C1(N=[N+]=[N-])c2cc(Br)ccc2Oc2cnc(Cl)cc21>>CC(CO)C1(N)c2cc(Br)ccc2Oc2cnc(Cl)cc21,,C1CCOC1,,[H-].[Na+],,test
US20130090298A1,Cc1ccc(S(=O)(=O)OC[C@H]2O[C@@H](c3ccc(Cl)c(Cc4ncc(-c5ccco5)s4)c3)[C@H](O)[C@@H](O)[C@@H]2O)cc1.[F-]>>O[C@H]1[C@H](c2ccc(Cl)c(Cc3ncc(-c4ccco4)s3)c2)O[C@H](CF)[C@@H](O)[C@@H]1O,,OCCO,,O,,test
US20020128270A1,CCI.Oc1ccc(I)cc1>>CCOc1ccc(I)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090286882A1,CCOC(=O)CC1(CCC(CCc2ccc(C(=O)OC)cc2)C(=O)O)CC1>>CCOC(=O)CC1(CCC(CO)CCc2ccc(C(=O)OC)cc2)CC1,,C1CCOC1,,[Cl-].[NH4+],,test
US20100292210A1,CN(Cc1ccc(Cl)nc1Cl)C[C@H](O)c1ccccc1>>CN1Cc2ccc(Cl)nc2O[C@H](c2ccccc2)C1,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20130324516A1,CNOC.O=C(O)c1cc(F)cc(Br)c1>>CON(C)C(=O)c1cc(F)cc(Br)c1,,ClCCl,O=S(Cl)Cl,CCN(CC)CC,Cl,test
US05280047,CC(=O)CC(=O)c1ccccc1.CCCCCCc1ccc(C=O)cc1>>CCCCCCc1ccc(/C=C(/C(C)=O)C(=O)c2ccccc2)cc1,C1CCNCC1,CCOCC,,,,test
US20140275085A1,C1CCNC1.COc1nc(SC)ncc1-c1ccc(Oc2ccnc(-c3cnn(C)c3)c2)c(C)n1>>COc1nc(N2CCCC2)ncc1-c1ccc(Oc2ccnc(-c3cnn(C)c3)c2)c(C)n1,,ClCCl,,O=C(OO)c1cccc(Cl)c1,,test
US20030171395A1,C[Si](C)(C)C#Cc1ncccc1NC(=O)C(F)(F)F>>c1cnc2cc[nH]c2c1,,CCO,,C,C[O-].[Na+],test
US20120196863A1,CC1(c2ccc(F)c(Br)c2)COCC(=O)N1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC1(c2ccc(F)c(Br)c2)COCC(=S)N1,,C1CCOC1,,,,test
US05422358,COc1cc(CCO)ccc1O.O=S(Cl)Cl>>COc1cc(CCCl)ccc1O,,ClCCl,,,,test
US20120022060A1,Clc1ccc2c(c1Nc1ccnc3[nH]c4c(c13)CNCC4)OCO2.O=C(Cl)C1CCC1>>O=C(C1CCC1)N1CCc2[nH]c3nccc(Nc4c(Cl)ccc5c4OCO5)c3c2C1,,ClCCCl,,CCN(C(C)C)C(C)C,,test
US20070208059A1,CC(C)CCS(=O)(=O)Cl.Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(O)cc1>>Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(OS(=O)(=O)CCC(C)C)cc1,,ClCCl,,CCN(CC)CC,O,test
US20120010247A1,CI.COC(=O)Cc1noc2cc(OC)ccc12>>COC(=O)C(C)c1noc2cc(OC)ccc12,,C1CCOC1,,O,[H-].[Na+],test
US20030018034A1,CCO.Cc1cc(C)c([N+](=O)[O-])c(C)c1C(=O)O>>CCOC(=O)c1c(C)cc(C)c([N+](=O)[O-])c1C,,CCO,,Cl,,test
US20020086891A1,COc1ccc2c(-c3ccc(C(F)(F)F)cc3)nsc2c1>>Oc1ccc2c(-c3ccc(C(F)(F)F)cc3)nsc2c1,,Br,CC(=O)O,,,test
US20130231329A1,C1CCNCC1.CN1CCC(OC(c2cccc(C=O)c2)c2nc3ccccc3[nH]2)CC1.O=C1CNC(=S)N1>>CN1CCC(OC(c2cccc(C=C3NC(=N)NC3=O)c2)c2nc3ccccc3[nH]2)CC1,,CCO,O,,,test
US20080312226A1,O=C(Nc1cnns1)OCC(Cl)(Cl)Cl.c1ccc(-c2csc(N3CCNCC3)n2)cc1>>O=C(Nc1cnns1)N1CCN(c2nc(-c3ccccc3)cs2)CC1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20100063054A1,CC(c1ccc2nc(N)cn2n1)c1nnc2ccc(Br)cn12.O=C(Cl)C1CC1>>CC(c1ccc2nc(NC(=O)C3CC3)cn2n1)c1nnc2ccc(Br)cn12,,ClCCl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20070105890A1,COC(=O)c1[nH]nc2c3nc(N4CCC[C@@H](NC(=O)OC(C)(C)C)C4)n(Cc4ccccc4Cl)c3c(=O)n(C)c12.Cl>>COC(=O)c1[nH]nc2c3nc(N4CCC[C@@H](N)C4)n(Cc4ccccc4Cl)c3c(=O)n(C)c12.Cl,,C1COCCO1,Cl,,,test
US20150361094A1,CCNC(=O)c1c(C)c(Cl)cc(C(C)N)c1-c1cc(F)cc(F)c1.Clc1ncnc2cccnc12>>CCNC(=O)c1c(C)c(Cl)cc(C(C)Nc2ncnc3cccnc23)c1-c1cc(F)cc(F)c1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20080114023A1,COc1cccc(S(=O)(=O)n2cc(CCNC(=O)OC(C)(C)C)c3ccncc32)c1>>COc1cccc(S(=O)(=O)n2cc(CCN)c3ccncc32)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030181485A1,CC(C)(C)OC(=O)N1CCc2[nH]c3ccc([N+](=O)[O-])cc3c2CC1>>CC(C)(C)OC(=O)N1CCc2[nH]c3ccc(N)cc3c2CC1,[Zn],CCO,,[Ca+2].[Cl-].[Cl-],,test
US20030064962A1,CC(C)(C)OC(=O)CBr.CC1C[C@@H](C(=O)Nc2ccccc2)n2c1ncc(N(Cc1cccc(C(F)(F)F)c1)C(=O)OCc1ccccc1)c2=O>>CC(C)(C)OC(=O)C[C@@]1(C)C[C@@H](C(=O)Nc2ccccc2)n2c1ncc(NCc1cccc(C(F)(F)F)c1)c2=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20130345215A1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1cc(F)c(F)c(F)c1>>CC(C)(C)OC(=O)N1CCN(c2c(F)cc(C=O)cc2F)CC1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130172278A1,CCc1ccc(Cc2sc([C@@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)c(C)c2C)cc1>>CCc1ccc(Cc2sc([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(C)c2C)cc1,,CO,,CC(=O)O,C[O-].[Na+],test
US20160264567A1,CN(C)C=O.FC(F)(F)Oc1ccc(Cl)nc1>>O=Cc1cc(Cl)ncc1OC(F)(F)F,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20070244154A1,CCOC(=O)[C@H](O[Si](C)(C)C(C)(C)C)[C@H](N)c1ccccc1.Cc1nc2c(n1C)CC(C(=O)N(C)C)CC2=O>>Cc1nc2c(n1C)CC(C(=O)N(C)C)C1=C2N[C@H](c2ccccc2)[C@@H](O)C1=O,,COCCO,,,,test
US20120028961A1,CC(C)(C)CCBr.N#Cc1ccc(C=O)cc1>>CC(C)(C)CCC(=O)c1ccc(C#N)cc1,,C1CCOC1,,II,,test
US20040147519A1,CCOC(=O)Cc1ccnc(C)c1>>Cc1cc(CCO)ccn1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150087639A1,O=C(O)CCc1ccco1>>O=C(O)CCC1CCCO1,[Pd],CO,,,,test
US20130045949A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cc1ccc(Br)c(C)c1>>Cc1ccc(B2OC(C)(C)C(C)(C)O2)c(C)c1,Cl[Pd]Cl,CN(C)C=O,,O,CC(=O)[O-].[K+],test
US20120010209A1,CCc1sc(C(=O)N[C@@H]2[C@@H](NC(=O)OCC3c4ccccc4-c4ccccc43)CCCC2(F)F)cc1-c1cnc2cccnn12>>CCc1sc(C(=O)N[C@@H]2[C@@H](N)CCCC2(F)F)cc1-c1cnc2cccnn12,,CN(C)C=O,,C1CCNCC1,,test
US20080045546A1,Nc1cccc2c1CC(=O)CC2.O=C(Cl)OCc1ccccc1>>O=C1CCc2cccc(NC(=O)OCc3ccccc3)c2C1,,C1CCOC1,,O,c1ccncc1,test
US04814349,CC(C)(C)NN.CC(C)=O>>CC(C)=NNC(C)(C)C,,CCOCC,,[K+].[OH-],,test
US20040220169A1,CC(=O)N1CCNCC1.O=C(NCc1nc2cc(Cl)ccc2[nH]1)c1ccc(C(=O)O)c(Cl)c1>>CC(=O)N1CCN(C(=O)c2ccc(C(=O)NCc3nc4cc(Cl)ccc4[nH]3)cc2Cl)CC1,,CS(C)=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US05714489,CCOC(=O)Cn1c(=O)c(=O)[nH]c2cc(C(F)(F)F)c(-n3ccc(C=O)c3)cc21.NCc1ccccc1>>CCOC(=O)Cn1c(=O)c(=O)[nH]c2cc(C(F)(F)F)c(-n3ccc(CNCc4ccccc4)c3)cc21,,CCO,,CC(=O)O,[BH3-]C#N.[Na+],test
US04582847,CC(=O)OC(C)=O.Cc1cc(Cn2c(-c3ccccc3)nc(Cl)c2CC(=O)O)ccc1O>>CC(=O)Oc1ccc(Cn2c(-c3ccccc3)nc(Cl)c2CC(=O)O)cc1C,,c1ccncc1,,,,test
US05863935,CN1CC=C(c2c[nH]c3ccc(C=O)cc23)CC1.O=C1CNC(=O)N1>>CN1CC=C(C(=C2NC(=O)NC2=O)c2ccc3[nH]ccc3c2)CC1,,CC(=O)O,,C,O=C[O-].[NH4+],test
US20120122843A1,C=O.FC(F)(F)CCC1CNCc2ccc(Cl)nc2O1>>CN1Cc2ccc(Cl)nc2OC(CCC(F)(F)F)C1,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150141402A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OC1CN(Cc2ccccc2)CC1(F)F>>CC(C)(C)OC(=O)N1CC(O)C(F)(F)C1,,CCO,,,,test
US20130261106A1,CC(C)Oc1cc(N2CCN(C)CC2)ccc1NC=O.CS(=O)(=O)c1ncc2sc(C(N)=O)c(-c3ccc(F)cc3)c2n1>>CC(C)Oc1cc(N2CCN(C)CC2)ccc1Nc1ncc2sc(C(N)=O)c(-c3ccc(F)cc3)c2n1,,CN(C)C=O,CO,[H-].[Na+],,test
US20080009482A1,C=CC(=O)NC.COCCN>>CNC(=O)CCNCCOC,,CO,,CCO,,test
US20100317657A1,CI.COc1ccc(-c2ccc3ncc4[nH]c(=O)n(-c5cn(C)nc5C)c4c3n2)cc1OC>>COc1ccc(-c2ccc3ncc4c(c3n2)n(-c2cn(C)nc2C)c(=O)n4C)cc1OC,,CN(C)C=O,,[H-].[Na+],,test
US20070173519A1,CC(C)(C)[Si](C)(C)Cl.CCOc1ccc(Nc2c(CCCO)c(Cl)nc3ccnn23)cc1>>CCOc1ccc(Nc2c(CCCO[Si](C)(C)C(C)(C)C)c(Cl)nc3ccnn23)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20120028042A1,C=CC[Si](OCC)(OCC)OCC.C[SiH](C)O[SiH](C)C>>CCO[Si](CCC[Si](C)(C)O[SiH](C)C)(OCC)OCC,[Pt],,,,,test
US05252749,BrCCBr.O=C1c2ccccc2C(=O)N1O>>O=C1c2ccccc2C(=O)N1OCCBr,,CN(C)C=O,,CCN(CC)CC,,test
US04034107,CN(C)CC(=O)Cl.COC(=O)NC(=S)Nc1ccc(SC#N)cc1N.Cl>>COC(=O)NC(=S)Nc1ccc(SC#N)cc1NC(=O)CN(C)C.Cl,,ClCCl,,,,test
US04224052,N#CC(c1ccccc1)C(CC(=O)Cl)c1ccccc1.OCC#CCO>>N#CC(c1ccccc1)C(CC(=O)OCC#CCO)c1ccccc1,,C1CCOC1,c1ccccc1,O,c1ccncc1,test
US20150152047A1,CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1cc(Cl)c(CN2CCC[C@H](N)C2)c(C(F)(F)F)c1.O=C(O)c1ccc[nH]1>>CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1cc(Cl)c(CN2CCC[C@H](NC(=O)c3ccc[nH]3)C2)c(C(F)(F)F)c1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04590189,COc1ccc(N2C(=O)C3=C(CCCC3)C2O)cc1.O=C(C=P(c1ccccc1)(c1ccccc1)c1ccccc1)N1CCCCC1>>COc1ccc(N2C(=O)C3=C(CCCC3)C2CC(=O)N2CCCCC2)cc1,,Cc1ccccc1,,,,test
US20100222581A1,C=CCO[C@@H]1C[C@H](C(=O)O)N(C(=O)OC(C)(C)C)C1.CCCO[C@@H]1C[C@H]([C@@H](O[Si](C)(C)C(C)(C)C)[C@H](Cc2cc(F)cc(F)c2)NC(=O)c2cc(Br)cc(C(=O)OC)c2)N(C(=O)OC(C)(C)C)C1.Nc1cc(C(=O)O)cc(N2CCCC2=O)c1>>CCCO[C@@H]1C[C@H]([C@@H](O[Si](C)(C)C(C)(C)C)[C@H](Cc2cc(F)cc(F)c2)NC(=O)c2cc(O)cc(N3CCCC3=O)c2)N(C(=O)OC(C)(C)C)C1,[Pd],CO,,,,test
US06184180B2,CCOC(=O)CCCCCCCCCCOc1ccc(O)cc1>>O=C(O)CCCCCCCCCCOc1ccc(O)cc1,,CCO,,[Na+].[OH-],,test
US20070043080A1,CC(C)C(=O)Nc1cccc(C2CCNCC2)c1.Cn1c(C=O)cc2ccccc21>>CC(C)C(=O)Nc1cccc(C2CCN(Cc3cc4ccccc4n3C)CC2)c1,,CC(=O)O,,,,test
US20070219229A1,CCn1ccc2c(Nc3cccc(Cl)c3)ncc(C(=O)N3CCOCC3)c21.Cl>>CCn1ccc2c(Nc3cccc(Cl)c3)ncc(C(=O)N3CCOCC3)c21.Cl,,CCOCC,,,,test
US20080146606A1,CNc1ccc(-c2ccnc3c2cc(C)n3S(=O)(=O)c2ccccc2)cc1>>CNc1ccc(-c2ccnc3[nH]c(C)cc23)cc1,,C1COCCO1,,[Na+].[OH-],,test
US20120196853A1,N#Cc1ccc(C(c2ccc3cccnc3c2O)N2CCOCC2)cc1.O=S(=O)(O)O>>NC(=O)c1ccc(C(c2ccc3cccnc3c2O)N2CCOCC2)cc1,,CCN(CC)CC,,O=C([O-])O.[Na+],,test
US20120252801A1,CCN1CC(C)(C)OC(=O)C1CC(=O)O.CNc1ccccc1>>CCN1CC(C)(C)OC(=O)C1CC(=O)N(C)c1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080176862A1,B1Oc2ccccc2O1.C#CC1CC1>>C(=C/C1CC1)\B1Oc2ccccc2O1,,C1CCOC1,,,,test
US20040053916A1,CC1(C)COC(c2ccc(C3CCC4(CC3)OCCO4)cc2)=N1.CCO>>CCOC(=O)c1ccc(C2CCC(=O)CC2)cc1,,CCO,,O=S(=O)(O)O,,test
US20150376130A1,CCCNc1cc(Cl)ccc1C(=O)OC>>CCCNc1cc(Cl)ccc1C(=O)O,,C1CCOC1,O,[Na+].[OH-],,test
US20120202785A1,C[C@H](N)C1=NC=C2C=C(F)CCC3=C2N1CC3.N#Cc1c(N)ncnc1Cl>>C[C@H](Nc1ncnc(N)c1C#N)C1=NC=C2C=C(F)CCC3=C2N1CC3,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20120184542A1,CN1CCN(CCNc2ncc3cc(C(=O)Nc4cc(C(=O)NC(CCNC(=O)OC(C)(C)C)c5ccccc5)ccc4Cl)c(=O)[nH]c3n2)CC1.Cl>>CN1CCN(CCNc2ncc3cc(C(=O)Nc4cc(C(=O)NC(CCN)c5ccccc5)ccc4Cl)c(=O)[nH]c3n2)CC1.Cl,,C1COCCO1,,,,test
US20070287701A1,COc1cc(F)c2ncc(N(C(=O)[O-])C(C)(C)C)c(Br)c2c1>>COc1cc(F)c2ncc(N)c(Br)c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100099665A1,C[C@H]1CN(Cc2cn(S(=O)(=O)c3ccccc3)c(=O)c3ccc(Br)cc23)CCN1C(=O)OC(C)(C)C>>C[C@H]1CN(Cc2c[nH]c(=O)c3ccc(Br)cc23)CCN1C(=O)OC(C)(C)C,,CN(C)C=O,O,[Na+].[OH-],,test
US20160137636A1,COc1cc(-c2cccc(F)c2)c(Cl)cc1-c1ncnc2cc(S(=O)(=O)Oc3c(F)c(F)c(F)c(F)c3F)ccc12.COc1ccc(CNc2cscn2)cc1>>COc1ccc(CN(c2cscn2)S(=O)(=O)c2ccc3c(-c4cc(Cl)c(-c5cccc(F)c5)cc4OC)ncnc3c2)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20030166639A1,CCOc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3ccnc(C4CCCC4)c3)c2)cc1C(F)(F)F>>CCOc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3ccnc(C4CCCC4)c3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130281663A1,C[C@H](N)C(=O)O.NCCCC[C@H](NC(=O)C(F)(F)F)C(=O)O.N[C@@H](CCC(=O)OCc1ccccc1)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O>>C[C@H](N)C(=O)O.NCCCC[C@H](N)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O,,C1COCCO1,O,CCNCC,,test
US20120135990A1,CC(C)(C)OC(=O)N1CC(O)C2C1CCN2C(=O)OCc1ccccc1.Cl>>Cl.O=C(OCc1ccccc1)N1CCC2NCC(O)C21,,Cc1ccccc1,ClCCl,C1COCCO1,,test
US20010053779A1,CC(c1nc2c([nH]1)CCN(C(=O)OCc1ccccc1)C2)c1nc2ccc(C(=O)O)cc2n1C.COC(=O)c1ccccc1OCCN>>COC(=O)c1ccccc1OCCNC(=O)c1ccc2nc(C(C)c3nc4c([nH]3)CCN(C(=O)OCc3ccccc3)C4)n(C)c2c1,,CN(C)C=O,ClCCCl,CCN(C(C)C)C(C)C,On1nnc2ccccc21,test
US07247645B2,O=C(COCCCO)CC(=O)OCCC(c1ccccc1)c1ccccc1.O=[Cr](=O)(O)O>>O=C(O)CCOCC(=O)CC(=O)OCCC(c1ccccc1)c1ccccc1,,CC(C)=O,CCOC(C)=O,O,O=S(=O)(O)O,test
US20120330037A1,CCCCc1oc2ccc([N+](=O)[O-])cc2c1C(=O)c1ccc(OCCCO)cc1>>CCCCc1oc2ccc(N)cc2c1C(=O)c1ccc(OCCCO)cc1,[Pd],CO,,,,test
US20070299070A1,CCN(C(C)C)C(C)C.CCOC(C)=O.CN(C)C=O.Nc1ccc(CO)cc1.O=C(O)c1cc2cc(O)ccc2[nH]1>>O=C(Nc1ccc(CO)cc1)c1cc2cc(OCc3ccccc3)ccc2[nH]1,,CCOC(C)=O,CN(C)C=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20070010670A1,COC(=O)c1ccc2c(c1)NCCO2.O=C(Cl)c1cc(Cl)c(O)c(Cl)c1>>COC(=O)c1ccc2c(c1)N(C(=O)c1cc(Cl)c(O)c(Cl)c1)CCO2,,CCOC(C)=O,,,,test
US20040122063A1,COC(=O)[C@H]1CC[C@H](N=[N+]=[N-])[C@H](NC(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N[C@@H]1C[C@@H](C(=O)O)CC[C@@H]1N=[N+]=[N-],,C1CCOC1,,O,[Li+].[OH-],test
US20090022664A1,COC(=O)CCC(=O)N1CC2C(C1)N2S(=O)(=O)c1c(C(C)C)cc(C(C)C)cc1C(C)C>>CC(C)c1cc(C(C)C)c(S(=O)(=O)N2C3CN(C(=O)CCC(=O)O)CC32)c(C(C)C)c1,,C1CCOC1,,[Na+].[OH-],,test
US20020022631A1,CCOC(=O)[C@@H](Cc1cccc([N+](=O)[O-])c1)NC(C)=O>>CC(=O)N[C@@H](CO)Cc1cccc([N+](=O)[O-])c1,,CCO,,[BH4-].[Na+],,test
US20110059957A1,Brc1csc(Br)n1.CC(=O)N1CCNCC1>>CC(=O)N1CCN(c2nc(Br)cs2)CC1,,CN(C)C=O,,CCN(CC)CC,O,test
US20120316193A1,C1CCNCC1.O=C(CCl)c1cnn(-c2ccc(Cl)cc2)c1>>O=C(CN1CCCCC1)c1cnn(-c2ccc(Cl)cc2)c1,,CC#N,,CCN(CC)CC,,test
US20150111876A1,CO.Cc1nc(Cl)c2cc(Br)sc2n1>>COc1nc(C)nc2sc(Br)cc12,,C1CCOC1,,O,[H-].[Na+],test
US20040157902A1,CC(C)(C)OC(=O)NCC(=O)NC(CC#N)c1ccc(-c2ccccc2)cc1>>N#CCC(NC(=O)CN)c1ccc(-c2ccccc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080293718A1,COC1CCc2cc(C3(c4cccc(Br)c4)N=C(N)N(C)C3=O)ccc2C1.COc1cc(OS(C)(=O)=O)cc(B2OC(C)(C)C(C)(C)O2)c1>>COc1cc(OS(C)(=O)=O)cc(-c2cccc(C3(c4ccc5c(c4)CCC(OC)C5)N=C(N)N(C)C3=O)c2)c1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20040009995A1,CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cnc(Cl)c(Br)c1.Cc1ncc(CN)c(N)n1.O=C(O)C(F)(F)F>>CSc1sc(C(=N)N)cc1S(=O)(=O)c1cnc(NCc2cncnc2N)c(Br)c1.O=C(O)C(F)(F)F,,C1CCOC1,,ClCCl,,test
US20150158851A1,CN(C)CCC(O)c1ccccc1.O=[N+]([O-])c1cn[nH]c1>>CN(C)CCC(c1ccccc1)n1cc([N+](=O)[O-])cn1,,C1CCOC1,O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120149691A1,N#Cc1cnn2cccc2c1NC1CCCCCC1.OO>>NC(=O)c1cnn2cccc2c1NC1CCCCCC1,,CCO,,[NH4+].[OH-],,test
US20160068496A1,CI.COc1cc(N)c(C(=O)O)cc1Br>>COC(=O)c1cc(Br)c(OC)cc1N,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120101086A1,Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(C#N)c3)s1)CCNC2.O=C[C@@H](O)CO>>Cc1c2c(nn1-c1nnc(-c3ccc(OC(C)C)c(C#N)c3)s1)CCN(C[C@@H](O)CO)C2,,CO,ClCCl,O=C([O-])O.[Na+],,test
US05760033,CS(=O)(=O)Cl.O=C(NC(CCO)c1ccccc1Br)c1c(F)cccc1F>>CS(=O)(=O)OCCC(NC(=O)c1c(F)cccc1F)c1ccccc1Br,,ClCCl,,CCN(CC)CC,O,test
US20090270475A1,CC(C)(C)OC(=O)NC(=N)N.[N-]=[N+]=Nc1ccc(C(=O)CBr)cc1>>CC(C)(C)OC(=O)n1c(-c2ccc(N=[N+]=[N-])cc2)cnc1N,,CN(C)C=O,,,,test
US20090117074A1,O=C(/C=C/c1ccn(S(=O)(=O)c2ccc3ncsc3c2)c1)NOC1CCCCO1>>O=C(/C=C/c1ccn(S(=O)(=O)c2ccc3ncsc3c2)c1)NO,,CO,,Cl,,test
US20110281888A1,CC(C)(C)[Si](C)(C)Cl.Cn1ccnc1[C@@H]1CC[C@@H](O)CC1>>Cn1ccnc1[C@@H]1CC[C@@H](O[Si](C)(C)C(C)(C)C)CC1,CN(C)c1ccncc1,ClCCl,,c1c[nH]cn1,,test
US20120157454A1,CC(C)(C)OC(=O)NCCCNCC(=O)Nc1ccc2[nH]c(=O)c3ccccc3c2c1.Cl>>Cl.NCCCNCC(=O)Nc1ccc2[nH]c(=O)c3ccccc3c2c1,,C1COCCO1,ClCCl,,,test
US20140364414A1,CN1C(=O)NS(=O)(=O)c2cc(Br)ccc21.COc1ccc(CCl)cc1>>COc1ccc(CN2C(=O)N(C)c3ccc(Br)cc3S2(=O)=O)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04259338,CCOC(=O)C1CCC(C)(O)C(C(=O)OCC)C1c1ccc2oc3c(c2c1)CCCC3>>O=C(O)CC(CC(=O)O)c1ccc2oc3c(c2c1)CCCC3,,C1COCCO1,O,CCO,[Na+].[OH-],test
US20100137281A1,CCCc1cc(C(=O)OC)c(N)s1.COc1ccc(CN)c(OC)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCCc1cc2c(=O)n(Cc3ccc(OC)cc3OC)c(=O)[nH]c2s1,,ClCCl,,CCN(CC)CC,,test
US20050176775A1,COC(=O)c1ccc(C)c(-n2c(C)cc(CBr)cc2=O)c1.Oc1ccc(F)cc1F>>COC(=O)c1ccc(C)c(-n2c(C)cc(COc3ccc(F)cc3F)cc2=O)c1,,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120208817A1,COC(=O)c1c(O)cc(C=O)cc1F.NC(N)=O.O=C(Cc1ccccc1)c1ccccc1>>O=C1NC(c2ccccc2)=C(c2ccccc2)C(c2cc(O)c(C(=O)O)c(F)c2)N1,,CCO,,Cl,,test
US04284631,CC(C)(C)OC(=O)NCCON.O=CNc1nc(C(=O)C(=O)O)cs1>>CC(C)(C)OC(=O)NCCON=C(C(=O)O)c1csc(NC=O)n1,,CO,,,,test
US20040014962A1,CC(C)N(CCO[Si](C)(C)C(C)(C)C)C(=O)c1csc(N2CC(O)C2)n1.CS(=O)(=O)Cl>>CC(C)N(CCO[Si](C)(C)C(C)(C)C)C(=O)c1csc(N2CC(OS(C)(=O)=O)C2)n1,,ClCCl,,CCN(CC)CC,,test
US06177440B1,CC(C)(C)OC(=O)CBr.NC(=O)c1cccc2c1c1c(O)cccc1n2Cc1cccc(F)c1>>CC(C)(C)OC(=O)COc1cccc2c1c1c(C(N)=O)cccc1n2Cc1cccc(F)c1,,CCOC(C)=O,CN(C)C=O,,,test
US20110301167A1,C=CCOC(C)C(=O)N(C)OC.C=C[Mg]Br>>C=CCOC(C)C(=O)C=C,,C1CCOC1,,Cl,,test
US20140221417A1,CC(=O)O.COc1ccc(N(C)C(=O)[C@H](Cc2cccc(C#N)c2)NC(=O)OC(C)(C)C)cc1>>COc1ccc(N(C)C(=O)[C@H](Cc2cccc(C=O)c2)NC(=O)OC(C)(C)C)cc1,[Ni],O,c1ccncc1,,,test
US20140088124A1,CC(C)(C)OC(=O)N1CCC(CO)CC1.CCOC(=O)C(Br)CC>>CCOC(=O)C(CC)OCC1CCN(C(=O)OC(C)(C)C)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US05811389,C=[N+]=[N-].CN1c2cccc(C(=O)OC(C)(C)C)c2Sc2c(CC(=O)O)ccc(CN)c21>>COC(=O)Cc1ccc(CN)c2c1Sc1c(C(=O)OC(C)(C)C)cccc1N2C,,ClCCl,,,,test
US06608085B1,FC(F)(F)c1cc(Br)c2cccc(C(F)(F)F)c2n1.O=C1CN(C(c2ccccc2)c2ccccc2)C1>>OC1(c2cc(C(F)(F)F)nc3c(C(F)(F)F)cccc23)CN(C(c2ccccc2)c2ccccc2)C1,,CCOCC,,O,[Li]CCCC,test
US20040030132A1,CCOc1c(OCC)c(=O)c1=O.COC(=O)[C@H](Cc1ccc(-c2cccc(N)c2)cc1)NS(=O)(=O)c1c(C)cc(C)cc1C>>CCOc1c(Nc2cccc(-c3ccc(C[C@H](NS(=O)(=O)c4c(C)cc(C)cc4C)C(=O)OC)cc3)c2)c(=O)c1=O,,CCCO,,,,test
US20090163464A1,CN.O=C(Cl)c1cccc(Br)n1>>CNC(=O)c1cccc(Br)n1,,C1CCOC1,,,,test
US20110015175A1,COc1cc(Nc2nc(C(CCCCCl)c3ccc(F)cc3)n[nH]2)ccc1-c1cnnc(C)c1>>COc1cc(Nc2nc3n(n2)CCCCC3c2ccc(F)cc2)ccc1-c1cnnc(C)c1,,CN(C)C=O,,[I-].[K+],,test
US05962002,C1CCNC1.Cc1ccc(S(=O)(=O)O)cc1.O=C1C=C(O)C(=O)c2ccccc21.c1ccccc1>>CC(C)(C)CCC=CC1=C(O)C(=O)c2ccccc2C1=O,,c1ccccc1,,C1CCOC1,,test
US20160257951A1,CC(=O)Cl.CCCCCCCCCCC(CCCCCCC/C=C\C[C@H](O)CCCCCC)OC(=O)OCCCN(C)C>>CCCCCCCCCCC(CCCCCCC/C=C\C[C@@H](CCCCCC)OC(C)=O)OC(=O)OCCCN(C)C,,ClCCl,,c1ccncc1,,test
US20070105831A1,COc1cccc(C=O)c1Cl.O=C(OO)c1cccc(Cl)c1>>COc1cccc(O)c1Cl,,ClCCl,,,,test
US05852019,ClCCNCCCl.Nc1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(N2CCNCC2)c1,,CCCCO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US05422353,CI.COCc1ccncc1>>COCc1cc[n+](C)cc1.[I-],,CC#N,,,,test
US20050288273A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCC(=O)C(Br)C3)C(=O)O1.CC(N)=S>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCc2nc(C)sc2C3)C(=O)O1,,CCO,,O=C([O-])O.[Na+],,test
US20080081907A1,CN(C)C=O.Cc1ccc(CNc2ccc3c(Br)cccc3n2)o1>>Cc1ccc(CNc2ccc3c(C=O)cccc3n2)o1,,C1CCOC1,,[Li]CCCC,,test
US20060069077A1,CN1C(=O)[C@@H]2CCCN2C[C@H]1CO.CS(=O)(=O)Cl>>CN1C(=O)[C@@H]2CCCN2C[C@H]1COS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20140051706A1,CC(=O)OC(C)=O.C[C@H]1C2N(C(=O)CN(C)N2C(=O)NCc2ccccc2)[C@@H](Cc2ccc(O)cc2)C(=O)N1Cc1cccc2cccnc12>>CC(=O)Oc1ccc(C[C@H]2C(=O)N(Cc3cccc4cccnc34)[C@@H](C)C3N2C(=O)CN(C)N3C(=O)NCc2ccccc2)cc1,,CCOC(C)=O,c1ccncc1,,,test
US20110319378A1,C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](C=O)C(C)C)C1=O.C[Mg]Br>>C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(C(C(C)C)[C@H](C)O)C1=O,,C1CCOC1,,,,test
US20120270857A1,COC(=O)c1cccc2nc(C(C)C)n(CC(OC)OC)c12>>COC(=O)c1cccc2nc(C)n(CC=O)c12,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20120157471A1,CN=C=O.Cn1c(-c2nc(N3CCNCC3)ccc2Cl)nc2ccccc21>>CNC(=O)N1CCN(c2ccc(Cl)c(-c3nc4ccccc4n3C)n2)CC1,,ClCCl,,O=CO,,test
US20100152165A1,CCOC(=O)/C=C/c1ccc(C)cc1F.O=C1CCC(=O)N1Br>>CCOC(=O)/C=C/c1ccc(CBr)cc1F,CC(C)(C#N)N=NC(C)(C)C#N,ClC(Cl)(Cl)Cl,,,,test
US20120295907A1,CCc1cc(C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)cc(C)c1NC(=O)c1cccc([N+](=O)[O-])c1F.CO>>CCc1cc(C(F)(C(F)(F)F)C(F)(F)C(F)(F)F)cc(C)c1NC(=O)c1cccc([N+](=O)[O-])c1OC,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20110263610A1,C[C@@H]1CNCCN1c1ccc(C(F)(F)F)cn1.ClCCl.N#Cc1ccc(-c2n[nH]nc2C=O)cc1>>C[C@@H]1CN(Cc2n[nH]nc2-c2ccc(C#N)cc2)CCN1c1ccc(C(F)(F)F)cc1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100063068A1,CC(C)(C)N.CNC(=O)c1c(-c2ccc(F)cc2)oc2ncc(-c3cccc(C(=O)O)c3)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ncc(-c3cccc(C(=O)NC(C)(C)C)c3)cc12,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050148634A1,CC(=O)Nn1c(S)nc2cc(OC(F)F)ccc21.Cl>>Cl.Nn1c(S)nc2cc(OC(F)F)ccc21,,CCO,,O,,test
US20120116045A1,C=C(C)C(=O)OC(=O)C(=C)C.CC(C)(C)OC(=O)Nc1cc(COc2ccc(O)cc2)cc(NC(=O)[O-])c1.CN(C)c1ccncc1>>C=C(C)C(=O)Oc1ccc(OCc2cc(NC(=O)OC(C)(C)C)cc(NC(=O)OC(C)(C)C)c2)cc1,CN(C)c1ccncc1,CCOC(C)=O,O,C1CCOC1,CCN(C(C)C)C(C)C,test
US20100298324A1,COc1cnc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)nc1OC.NCc1ccncc1>>COc1cnc(-n2c(=S)[nH]c3cc(C(=O)NCc4ccncc4)ccc3c2=O)nc1OC,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US03979397,COc1cc2c(cc1OC)-c1c(C#N)sc(=N)n1CC2.O=C(Cl)c1ccccc1>>COc1cc2c(cc1OC)-c1c(C#N)sc(=NC(=O)c3ccccc3)n1CC2,,O,,c1ccncc1,,test
US20050113419A1,CCCc1c(OCCC(NC)OCCCBr)ccc2c(C(F)(F)F)noc12.O=C=Nc1ccccc1>>CCCc1c(OCCCN(C)C(=O)Nc2ccccc2)ccc2c(C(F)(F)F)noc12,,c1ccncc1,,,,test
US20040186160A1,O=C1Cc2cc(F)ccc2N1.O=Cc1[nH]c2c(c1CCC(=O)O)CCCCC2>>O=C(O)CCc1c(/C=C2\C(=O)Nc3ccc(F)cc32)[nH]c2c1CCCCC2,,CCO,,C1CCNCC1,,test
US04536346,CCOC(=O)c1ccc(N)cc1.COc1ccc(C=CC(=O)Cl)cc1>>CCOC(=O)c1ccc(NC(=O)C=Cc2ccc(OC)cc2)cc1,,ClCCl,,CCN(CC)CC,,test
US20150166512A1,COc1ccc(CNc2ncnc(Cl)c2CCCl)cc1>>COc1ccc(CN2CCc3c(Cl)ncnc32)cc1,,O,,CN(C)C=O,,test
US20110105553A1,Cc1ccc(C(=O)c2c(O)c3cc(C)ccc3[nH]c2=S)cc1.NOS(=O)(=O)O>>Cc1ccc(-c2nsc3[nH]c4ccc(C)cc4c(=O)c23)cc1,,CO,,[Li+].[OH-],,test
US20080058378A1,CS(=O)(=O)O.Cc1cc(F)c2[nH]c(=O)n(C3CCN(C4CCOCC4)CC3)c2c1>>CS(=O)(=O)O.Cc1cc(F)c2[nH]c(=O)n(C3CCN(C4CCOCC4)CC3)c2c1,,CCCO,,CC#N,,test
US20130059834A1,CC(NS(=O)C(C)(C)C)C1CN(C(=O)OC(C)(C)C)C1>>CC(N)C1CN(C(=O)OC(C)(C)C)C1,,CO,,C1COCCO1,Cl,test
US20160016968A1,NC(=NO)C1CC1.O=C(O)c1cc(OCC(F)(F)F)c(C2CC2)cn1>>FC(F)(F)COc1cc(-c2nc(C3CC3)no2)ncc1C1CC1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20080027107A1,N#CCN1CCCCC1CO>>NCCN1CCCCC1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20030166639A1,CC(C)(C)OC(=O)Nc1cc(OCC(F)(F)F)c(C(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-c2ccnc(N3CCOCC3)c2)c1>>O=C1CC(c2cccc(-c3ccnc(N4CCOCC4)c3)c2)=Nc2cc(OCC(F)(F)F)c(C(F)(F)F)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150322045A1,CC(C)C(CO)NC(=O)OC(C)(C)C.O=C1NC(=O)c2ccccc21>>CC(C)C(CN1C(=O)c2ccccc2C1=O)NC(=O)OC(C)(C)C,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140094459A1,N#CCC(=O)N1CCC[C@@H]1Cn1nc(-c2ccc(Oc3cccc(F)c3)cc2)c2c(N)ncnc21.O=CC1CC1>>N#CC(=CC1CC1)C(=O)N1CCC[C@@H]1Cn1nc(-c2ccc(Oc3cccc(F)c3)cc2)c2c(N)ncnc21,,CO,,C1CCNCC1,,test
US20030216385A1,O=C(NNC(=S)Nc1ccccc1F)c1ccc(-c2ccccc2)cc1>>Fc1ccccc1-n1c(S)nnc1-c1ccc(-c2ccccc2)cc1,,[Na+],[OH-],Cl,,test
US05185446,CO.Fc1ccccc1-c1cn2c(Cl)nc3c(c2n1)CCCC3>>COc1nc2c(c3nc(-c4ccccc4F)cn13)CCCC2,,CC(=O)O,,[Na],,test
US20130096130A1,C=CC(=O)OC.C=CCC[C@@H](c1cccc(F)c1F)[C@H](NC(=O)OC(C)(C)C)c1scnc1Br>>COC(=O)/C=C/CC[C@@H](c1cccc(F)c1F)[C@H](NC(=O)OC(C)(C)C)c1scnc1Br,,ClCCl,,,,test
US20050215560A1,CC(Cl)CNc1cnn(C)c(=O)c1Cl.Fc1ccc2c(C3CCNCC3)noc2c1>>Cn1ncc(NCCCN2CCC(c3noc4cc(F)ccc34)CC2)c(Cl)c1=O,,CC#N,,[I-].[K+],,test
US20060287522A1,COc1cc(C(=O)N2Cc3ccc(C(=O)C(Cl)(Cl)Cl)n3Cc3ccccc32)ccc1-c1ccccc1C.NCc1cccnc1>>COc1cc(C(=O)N2Cc3ccc(C(=O)NCc4cccnc4)n3Cc3ccccc32)ccc1-c1ccccc1C,,CC#N,,CS(C)=O,,test
US20040180912A1,BrCCOC1CCCCO1.C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1cccc(O)c1>>C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1cccc(OCCOC2CCCCO2)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160068513A1,COC(=O)C1CCCN1c1nc(Nc2cc(C(C)C)n[nH]2)c2c(n1)C(C)(C)CC2.Nc1nccs1>>CC(C)c1cc(Nc2nc(N3CCCC3C(=O)Nc3nccs3)nc3c2CCC3(C)C)[nH]n1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20110207815A1,COCC(C)(COC)C(=O)NCCCN(C)CC[C@@]1(O)CCc2cc(F)ccc2[C@@H]1C(C)C>>COCC(C)(CNCCCN(C)CC[C@@]1(O)CCc2cc(F)ccc2[C@@H]1C(C)C)COC,,C1CCOC1,,,,test
US20120022080A1,NC(c1ccccc1)c1ccccc1.O=C(CCl)Nc1ccc(Cl)cc1C(=O)O>>O=C(CNC(c1ccccc1)c1ccccc1)Nc1ccc(Cl)cc1C(=O)O,,CCOC(C)=O,CN(C)C=O,[I-].[Na+],,test
US20140135277A1,CCOc1ccc(Cc2cc([C@@H]3O[C@H](OC)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)ccc2Cl)cc1>>CCOc1ccc(Cc2cc([C@@H]3O[C@H](OC)[C@@H](O)[C@H](O)[C@H]3O)ccc2Cl)cc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US06159901,COC(=O)c1cc(C)cc(Oc2cccc(C(F)(F)F)c2)n1.NN>>Cc1cc(Oc2cccc(C(F)(F)F)c2)nc(C(=O)NN)c1,,CO,,O,,test
US20090215742A1,COCOc1cc(OCOC)c(C(=O)N2Cc3ccccc3C2C(=O)OC)cc1Cl>>COCOc1cc(OCOC)c(C(=O)N2Cc3ccccc3C2C(=O)O)cc1Cl,,CO,O,[Li+].[OH-],,test
US20130102776A1,COc1ccc2c(c1CN1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccc(S(C)(=O)=O)cc13)C2=O>>COc1ccc2c(c1CN1CCNCC1)O/C(=C\c1n[nH]c3ccc(S(C)(=O)=O)cc13)C2=O,,C1COCCO1,ClCCl,Cl,,test
US20090137595A1,Nc1cccc(O)c1.O=C(Nc1cn2nc(I)ccc2n1)C1CCOCC1>>Nc1cccc(Oc2ccc3nc(NC(=O)C4CCOCC4)cn3n2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040171543A1,COC(=O)c1cc(Br)cs1.O=[N+]([O-])c1ccc(B(O)O)cc1>>COC(=O)c1cc(-c2ccc([N+](=O)[O-])cc2)cs1,,COCCOC,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20080027070A1,Nc1ccc(Cl)c(C(=O)O)c1.O=C(Cl)c1cccc(C(F)(F)F)c1>>O=C(Nc1ccc(Cl)c(C(=O)O)c1)c1cccc(C(F)(F)F)c1,,C1CCOC1,,,,test
US20130129753A1,CO[C@H]([C@@H](C)C(=O)O)[C@@H]1CCCN1C(=O)OC(C)(C)C.NCCC1C=CC=CC=C1>>CO[C@H]([C@@H](C)C(=O)NCCC1C=CC=CC=C1)[C@@H]1CCCN1C(=O)OC(C)(C)C,,CN(C)C=O,ClCCl,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070142634A1,C=CC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C.CNC>>CN(C)CCC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C,,CO,,,,test
US20160095858A1,C[C@@H]1CN(c2ncccc2C(=O)O)C(C)(C)C1.O=C(OCc1ccccc1)N1CCNCC1.O=C=NS(=O)(=O)Cl>>C[C@@H]1CN(c2ncccc2C(=O)NS(=O)(=O)N2CCN(C(=O)OCc3ccccc3)CC2)C(C)(C)C1,,ClCCl,,c1ccncc1,,test
US20110288063A1,CC12CCC(CC1=O)C2(C)C.CCOC(=O)C(=O)OCC>>CC12CCC(C(=C(O)C(=O)O)C1=O)C2(C)C,,C1CCOC1,,[H-].[Na+],,test
US20120220622A1,CC1(C)OB(c2ccc3c(c2)CN(C2CC2)C3=O)OC1(C)C.CCN1C(=O)CN(Cc2ccc(Br)cc2Cl)C1=O>>CCN1C(=O)CN(Cc2ccc(-c3ccc4c(c3)CN(C3CC3)C4=O)cc2Cl)C1=O,,C1COCCO1,O,C1CCC(P(C2CCCCC2)C2CCCCC2)CC1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20080009486A1,COC(=O)CN1C(=O)CC(c2cccc(Cl)c2)C2(C(=O)N(C(=O)OC(C)(C)C)c3cc(Cl)ccc32)C1c1ccccc1C>>COC(=O)CN1C(=O)CC(c2cccc(Cl)c2)C2(C(=O)Nc3cc(Cl)ccc32)C1c1ccccc1C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150175623A1,CN1CCN(CCO)CC1.Oc1ccc(Br)cc1Cl>>CN1CCN(CCOc2ccc(Br)cc2Cl)CC1,,Cc1ccccc1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160264567A1,C[C@@H]1N[C@H](C(=O)NCc2cc(-c3cnc(C(F)(F)F)nc3)ncc2Br)C[C@H]1F.O=S(=O)(Cl)c1ccc(F)cc1>>C[C@H]1[C@H](F)C[C@@H](C(=O)NCc2cc(-c3cnc(C(F)(F)F)nc3)ncc2Br)N1S(=O)(=O)c1ccc(F)cc1,,ClCCl,,Cl,,test
US05750526,CCOP(=O)(OCC)C1CCc2cc(C(F)(F)F)cc3[nH]c(=O)c(=O)n1c23>>O=c1[nH]c2cc(C(F)(F)F)cc3c2n(c1=O)C(P(=O)(O)O)CC3,,CC#N,,C[Si](C)(C)Br,,test
US20120115843A1,CN1CCNCC1.N#Cc1ccnc(N2CC[C@H](S(=O)(=O)c3ccc(F)cc3Cl)C2)n1>>CN1CCN(c2ccc(S(=O)(=O)[C@H]3CCN(c4nccc(C#N)n4)C3)c(Cl)c2)CC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20090239854A1,C=Cc1cnc(C)nc1.CN1CCc2[nH]c3ccc(Cl)cc3c2C1>>Cc1ncc(CCn2c3c(c4cc(Cl)ccc42)CN(C)CC3)cn1,,CN1CCCC1=O,O,[K+].[OH-],,test
US06737425B1,C=CC(=O)Nc1ccc(F)cc1.c1ccc(CN2CCNCC2)cc1>>O=C(CCN1CCN(Cc2ccccc2)CC1)Nc1ccc(F)cc1,,CO,,,,test
US20080269300A1,CN(C)CCCl.N#Cc1c(N)nc(SCc2ccccc2)c(C#N)c1-c1ccc(O)cc1>>CN(C)CCOc1ccc(-c2c(C#N)c(N)nc(SCc3ccccc3)c2C#N)cc1,,CCO,,Cl,CC(C)(C)[O-].[K+],test
US20110206783A1,C=C(C)c1cc(C(=O)O)cc(Cl)n1.CO>>C=C(C)c1cc(C(=O)OC)cc(Cl)n1,,CO,ClCCl,C[Si](C)(C)C=[N+]=[N-],,test
US20080249091A1,CCOC(=O)c1cc2ccc(O)cc2n1-c1ccc(OC(C)C)cc1.Clc1cccc(Cl)n1>>CCOC(=O)c1cc2ccc(Oc3cccc(Cl)n3)cc2n1-c1ccc(OC(C)C)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04454338,CC(C(=O)O)c1ccccc1.CS(=O)(=O)Oc1ccc2cc(C(=N)N)ccc2c1>>CC(C(=O)Oc1ccc2cc(C(=N)N)ccc2c1)c1ccccc1,,c1ccncc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05721255,CS(=O)(=O)OS(C)(=O)=O.Nc1ccc(OC2CCCC2)cc1>>CS(=O)(=O)Nc1ccc(OC2CCCC2)cc1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20030162818A1,CCCCCCCCCC(=O)Cl.NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCC2CCCCC2)c1>>CCCCCCCCCC(=O)NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCC2CCCCC2)c1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20090325987A1,CI.O=c1[nH]c2cccc([N+](=O)[O-])c2c(=O)n1CC1CC1>>Cn1c(=O)n(CC2CC2)c(=O)c2c([N+](=O)[O-])cccc21,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20110098288A1,CS(=O)(=O)Nc1ccccc1N.O=[N+]([O-])c1cnc(Cl)nc1Cl>>CS(=O)(=O)Nc1ccccc1Nc1nc(Cl)ncc1[N+](=O)[O-],,C1CCOC1,,CCN(C(C)C)C(C)C,O,test
US20080108594A1,Nc1cccnc1Cl.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1cccnc1Cl)C(F)(F)F,,ClCCl,,,,test
US20130096084A1,CC(C)(C)OC(=O)N1CCC[C@@H](N)C1.O=C(O)c1ccc2c(c1)c(Br)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@@H](NC(=O)c2ccc3c(c2)c(Br)nn3C(c2ccccc2)(c2ccccc2)c2ccccc2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140162076A1,O=C(/C=C/c1ccc(OC(=O)c2ccc(C(=O)c3ccccc3)cc2)cc1)OCCc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]>>Nc1ccc(CCOC(=O)/C=C/c2ccc(OC(=O)c3ccc(C(=O)c4ccccc4)cc3)cc2)c(N)c1,[Zn],CN(C)C=O,O,CCCCCC,,test
US20110118314A1,CC(C)(C)OC(=O)N1CCCC(CBr)C1.COc1cc(F)c(F)cc1-c1ccc(O)cc1>>COc1cc(F)c(F)cc1-c1ccc(OCC2CCCNC2)cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20080021023A1,CCOC(=O)c1ccc2c(c1)N(CC(=O)OC(C)(C)C)C(=O)CO2>>CCOC(=O)c1ccc2c(c1)N(CC(=O)O)C(=O)CO2,,ClCCl,O=C(O)C(F)(F)F,CC#N,O,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Nc1ccc2[nH]c(=O)[nH]c2c1>>COc1ccc2nc(Nc3ccc4[nH]c(=O)[nH]c4c3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US06372740B1,CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(C)c2cnc(-c3ccccc3)nc21.Cl>>CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(C)c2cnc(-c3ccccc3)nc21.Cl,,CCO,,,,test
US20090069288A1,CC(C)Oc1ccc(-c2cc(CO)no2)cc1Cl.N#Cc1ccc(O)cc1>>CC(C)Oc1ccc(-c2cc(COc3ccc(C#N)cc3)no2)cc1Cl,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110263899A1,CC(=O)OC(C)=O.COCC(N)C(=O)O>>COCC(NC(C)=O)C(=O)O,,O,,C1CCOC1,,test
US04409017,CCOC(=O)C(C)Br.CN(c1ccc(O)cc1)c1cc2ccc(Cl)cc2cn1>>CCOC(=O)C(C)Oc1ccc(N(C)c2cc3ccc(Cl)cc3cn2)cc1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140039203A1,O=C(O)CC1(CC(=O)O)CC1>>O=C1CC2(CC2)CC(=O)O1,,Cc1cc(C)cc(C)c1,,CC(=O)OC(C)=O,,test
US04435326,CCSC1=CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C.S>>CCS[C@@]1(S)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C,,ClC(Cl)Cl,ClCCl,CCOCC,FB(F)F,test
US04657915,O=c1ccc2c(Br)nccc2[nH]1.c1nc[nH]n1>>O=c1ccc2c(-n3cncn3)nccc2[nH]1,,CN(C)C=O,,,,test
US20140088079A1,CI.COc1ccc(Cc2cc(C3O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)c3c(c2Br)CCC3)cc1>>COc1ccc(Cc2cc(C3O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)c3c(c2C)CCC3)cc1,,C1CCOC1,,[Li]CCCC,,test
US20090298807A1,O=C(O)Cc1cc(F)cc(CBr)c1>>OCCc1cc(F)cc(CBr)c1,,C1CCOC1,,B,CSC,test
US20070078136A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(Nc2cc(Cl)nn3ccnc23)cc1>>CC(C)(C)OC(=O)Nc1ccc(Nc2cc(Cl)nn3ccnc23)cc1,,C1CCOC1,,,,test
US20120083469A1,CC1(C)OB(CCCCBr)OC1(C)C.CCOC(=O)CN=C(c1ccccc1)c1ccccc1>>CCOC(=O)C(CCCCB1OC(C)(C)C(C)(C)O1)N=C(c1ccccc1)c1ccccc1,,CCOC(C)=O,,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20040162303A1,CC(N)CO.COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(S(=O)(=O)CCCCl)CC2)nc1N>>COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(S(=O)(=O)CCCNC(C)CO)CC2)nc1N,,C1CCOC1,,[I-].[Na+],,test
US04183909,Br.NC(=O)[C@H](NC(=O)OCc1ccccc1)c1ccccc1>>Br.NC(=O)[C@H](N)c1ccccc1,,CC(=O)O,CCOCC,,,test
US05698697,CC(C)(C)O.N#CC1CNCCN1>>CC(C)(C)NC(=O)C1CNCCN1,,O=S(=O)(O)O,,O,[Na+].[OH-],test
US20030236240A1,C=CCO.Fc1cc(F)cc(Br)c1>>C=CCOc1cc(F)cc(Br)c1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20150031708A1,COc1cc(C)c(B(O)O)cn1.Cc1cc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)nc(Cl)c1C>>COc1cc(C)c(-c2nc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)cc(C)c2C)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US06372749B1,CCCCc1cc(Cl)n2nccc2n1.CCOP(=O)(CSC)OCC>>CCCCc1cc(CSCP(=O)(OCC)OCC)n2nccc2n1,,C1CCOC1,CCOC(C)=O,[Li]CCCC,,test
US20050288293A1,CCOC(=O)c1cn2c(c1O)C(=O)N(Cc1ccccc1)CC2>>O=C(O)c1cn2c(c1O)C(=O)N(Cc1ccccc1)CC2,,CCO,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US04753941,Nc1ccc2ccc(Cl)nc2n1.O=C(O)C1=CSCCO1>>O=C(Nc1ccc2ccc(Cl)nc2n1)C1=CSCCO1,,O,,,,test
US20130267493A1,COC(=O)c1c[nH]c2cc(Cl)c(-c3ccc(OC[C@@H]4CCCN4C(=O)OC(C)(C)C)c(OC)c3)cc12>>COC(=O)c1c[nH]c2cc(Cl)c(-c3ccc(OC[C@@H]4CCCN4)c(OC)c3)cc12,,ClCCl,,Cl,,test
US20100125062A1,O=C(c1ccc(Oc2ncccc2Br)cc1)c1nc2ccccc2[nH]1.O=C1C=CCC1>>O=C1C=C(c2cccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)CC1,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,C1COCCO1,,,,test
US20100120858A1,CC(C)(C)OC(=O)N1CCC[C@H](COc2ccc(F)cc2Oc2ccccc2)C1.ClCCl.O=C(O)C(F)(F)F>>O=C(O)/C=C(/C(=O)O)N1CCC[C@H](COc2ccc(F)cc2Oc2ccccc2)C1,,ClCCl,,,,test
US20050065163A1,CCOC(C)=O.CI.O=C(O)c1cc(S)c2ccc(Cl)cc2n1>>COC(=O)c1cc(SC)c2ccc(Cl)cc2n1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20160102107A1,Cc1cc(N2C(=O)c3c(C4CC4)nn(C)c3C2c2ccc(Cl)cc2)cn2c(C)nnc12>>Cc1cc(N2C(=O)c3c(C4CC4)nn(C)c3[C@@H]2c2ccc(Cl)cc2)cn2c(C)nnc12,,CCOCC,,CO,,test
US20010027196A1,CS(=O)c1nc(N)nc(-c2ccccn2)c1C#N.Cc1cccnc1CO>>Cc1cccnc1COc1nc(N)nc(-c2ccccn2)c1C#N,,COCCOC,,C1CCC2=NCCCN2CC1,,test
US20140364413A1,COc1cc2ccccc2nc1/C=C/c1nc2c(N3CCOCC3)ccnn2c1-c1ccc(C(=O)OC(C)(C)C)cc1>>COc1cc2ccccc2nc1/C=C/c1nc2c(N3CCOCC3)ccnn2c1-c1ccc(C(=O)O)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060211682A1,CC(C)(C)OC(=O)N[C@@H](CC(=O)O)Cc1cc(F)c(F)cc1F.C[C@@H]1CCN[C@H](C)C(=O)N1>>C[C@@H]1CCN(C(=O)C[C@@H](Cc2cc(F)c(F)cc2F)NC(=O)OC(C)(C)C)[C@H](C)C(=O)N1,,CO,ClCCl,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20110269652A1,CCCCCCCCCCCCCCOCC(COCCCCCCCCCCCCCC)(CN1CCCC1)CN1CCCC1>>CCCCCCCCCCCCCCOCC(COCCCCCCCCCCCCCC)(CN1CCCC1)CN1CCCC1,,[Na+],[OH-],Cl,Cl,test
US04159273,CCCc1c2c(cc3c(=O)cc(C(=O)OCC)oc13)CCCC2.O=[N+]([O-])O>>CCCc1c2c(c([N+](=O)[O-])c3c(=O)cc(C(=O)OCC)oc13)CCCC2,,O=S(=O)(O)O,,O,,test
US20100029718A1,O=C(OC(=O)C(F)(F)F)C(F)(F)F.O=C1CCCN1>>O=C1CCCN1C(=O)C(F)(F)F,,Cc1ccccc1,,,,test
US20080153868A1,CC(C)(C)OC(=O)N1Cc2ccccc2C[C@H]1[C@H]1OC(=O)N[C@H]1Cc1cc(F)cc(F)c1>>O=C1N[C@@H](Cc2cc(F)cc(F)c2)[C@@H]([C@@H]2Cc3ccccc3CN2)O1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04156732,CNS(=O)(=O)c1cc(C(=O)Cl)ccc1Cl.Cc1cc2ccccc2[nH]1>>CNS(=O)(=O)c1cc(C(=O)c2c(C)[nH]c3ccccc23)ccc1Cl,,CC(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20160108027A1,CC1CCC(CCO)NC1.COc1cc(C(=O)O)cc2nc(NCc3cc(Cl)ccn3)oc12>>COc1cc(C(=O)N2CC(C)CCC2CCO)cc2nc(NCc3cc(Cl)ccn3)oc12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110201604A1,CC(C)(C)OC(=O)N1CC[C@H](N)C1.Cn1c(Nc2nc3ccc(Cl)cc3s2)nc2cc(C(=O)O)ccc21>>Cn1c(Nc2nc3ccc(Cl)cc3s2)nc2cc(C(=O)N[C@H]3CCN(C(=O)OC(C)(C)C)C3)ccc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060264448A1,COC(=O)c1nc(N)c2c(n1)N(Cc1ccccc1)C(OC)N2>>COC1Nc2c(N)nc(C(=O)O)nc2N1Cc1ccccc1,,CO,,Cl,[Na+].[OH-],test
US20110178063A1,C#CC(=O)OCC.C[Si](C)(C)N=[N+]=[N-]>>CCOC(=O)c1cn[nH]n1,,CO,,,,test
US20040259910A1,CCOCCBr.CCOc1cccc(Cc2ncc(C=O)c3cc(O)c(OC)cc23)c1>>CCOCCOc1cc2c(C=O)cnc(Cc3cccc(OCC)c3)c2cc1OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140275087A1,Cn1cnc(S(=O)(=O)N2C[C@@H](NC(=O)c3cc(C(F)(F)F)ccc3[N+](=O)[O-])[C@H](c3ccccc3)C2)c1>>Cn1cnc(S(=O)(=O)N2C[C@@H](NCc3cc(C(F)(F)F)ccc3N)[C@H](c3ccccc3)C2)c1,,C1CCOC1,,,,test
US03989711,CCCCCCCCCCCC(=O)OCCl.CCN(CC)CC>>CCCCCCCCCCCC(=O)OC[N+](CC)(CC)CC.[Cl-],,CCOCC,,,,test
US05948775,COc1ccc(C2Nc3c(OC)cccc3C(=O)N2c2ccc(OCCCl)cc2)cc1>>COc1ccc(-c2nc3c(OC)cccc3c(=O)n2-c2ccc(OCCCl)cc2)cc1,,Cc1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20150274628A1,CCCCCCCCCCCCCC1=C(O)C(=O)C=C(N(C)CCCC(=O)OCCCCCC)C1=O.COS(=O)(=O)OC>>CCCCCCCCCCCCCC1=C(OC)C(=O)C=C(N(C)CCCC(=O)OCCCCCC)C1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20020028832A1,CC(C)(C)[Si](Oc1ccc(OCC2CO2)cc1)(c1ccccc1)c1ccccc1.NCCc1ccc(NC2CCN(C(=O)NCc3ccccc3C(F)(F)F)CC2)cc1>>O=C(NCc1ccccc1C(F)(F)F)N1CCC(Nc2ccc(CCNC[C@H](O)COc3ccc(O)cc3)cc2)CC1,,CO,ClC(Cl)Cl,O=CO,,test
US20160251339A1,COc1ccc(S(=O)(=O)n2ccc3cc(C#N)ccc32)cc1N1CCN(C(=O)C(Cl)(Cl)Cl)CC1>>COc1ccc(S(=O)(=O)n2ccc3cc(C#N)ccc32)cc1N1CCNCC1,,C1CCOC1,,[K+].[OH-],,test
US03991202,BrCCOc1ccc(Br)cc1.Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1>>Clc1ccc(COC(Cn2cc[n+](CCOc3ccc(Br)cc3)c2)c2ccc(Cl)cc2Cl)c(Cl)c1.[Br-],,CC#N,,,,test
US20060160879A1,CCOC(=O)c1c(NC(=O)c2ccc(Cl)cc2)c2ccc(-c3ccc(C(=O)O)cc3)cc2n1Cc1cccc(Cl)c1>>CCOC(=O)c1c(NC(=O)c2ccc(Cl)cc2)c2ccc(-c3ccc(CO)cc3)cc2n1Cc1cccc(Cl)c1,,C1CCOC1,,CC(=O)O,,test
US06201006B1,CCOC(=O)C(c1ccccc1)N1CCC[C@H]1CCc1cc2ccc(C(=N)N)cc2n1C>>Cn1c(CC[C@@H]2CCCN2C(C(=O)O)c2ccccc2)cc2ccc(C(=N)N)cc21,,Cl,,,,test
US20120028974A1,COc1ccc(-c2cccc(C#N)c2)n2nc(C3(CO)CC3)nc12.O=C(Cl)N1CCCC1>>COc1ccc(-c2cccc(C#N)c2)n2nc(C3(COC(=O)N4CCCC4)CC3)nc12,,CN(C)C=O,O,[H-].[Na+],,test
US20140378540A1,CC(=O)OC[C@H]1O[C@@H](c2ccc(C#N)c(Cc3ccc(OCC=O)cc3)c2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.CON>>CON=CCOc1ccc(Cc2cc([C@@H]3O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)ccc2C#N)cc1,,CCO,,Cl,c1ccncc1,test
US20090176823A1,CNC(=O)OCCc1ccc(Cl)c(CN(C(=O)OC(C)(C)C)C2CC2)c1>>CNC(=O)OCCc1ccc(Cl)c(CNC2CC2)c1,,ClCCl,,Cl,,test
US20140303143A1,COC(=O)c1cccc2c1CC1(CC2)OCCO1>>OCc1cccc2c1CC1(CC2)OCCO1,,C1CCOC1,,CC(C)C[AlH]CC(C)C,,test
US04174317,CN(C)CCCN=Cc1ccc2ccccc2c1.ClCCl.O=C(OC(=O)C(Cl)(Cl)Cl)C(Cl)(Cl)Cl>>CN(C)CCCN1C(=O)C(Cl)(Cl)C1c1ccc2ccccc2c1.Cl,,ClCCl,,Cc1ccccc1C,,test
US20100324024A1,CC(C)(C)OC(=O)N1CCC(c2nc3ccccc3[nH]2)CC1.CI>>Cn1c(C2CCN(C(=O)OC(C)(C)C)CC2)nc2ccccc21,,CC(C)=O,,[K+].[OH-],,test
US20090118500A1,COC(=O)c1ccc(C(=O)NCCCc2ccncc2)s1.NN>>NNC(=O)c1ccc(C(=O)NCCCc2ccncc2)s1,,CO,,O,,test
US04128716,CCOC(=O)c1cnn2c1c(OCC)nc1ccccc12>>CCOc1nc2ccccc2n2ncc(C(=O)O)c12,,CCO,,[Na+].[OH-],,test
US20080085887A1,CC(N)Cc1ccc(F)c(F)c1.Nc1ccnc(C(F)(F)F)c1C(=O)O>>CC(Cc1ccc(F)c(F)c1)NC(=O)c1c(N)ccnc1C(F)(F)F,,CN(C)C=O,ClCCl,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US07176310B1,COC(=O)COc1ncc(C(=O)Nc2ccc(F)cc2)cn1.OC1CCCCC1>>O=C(COc1ncc(C(=O)Nc2ccc(F)cc2)cn1)OC1CCCCC1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20130183269A1,CCOC(=O)C1(C(=O)OC(C)(C)C)CC2CC(=O)CC2C1>>CCOC(=O)C1CC2CC(=O)CC2C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100029650A1,CC(C)OC(=O)N1CCC(COc2ccc(Br)cc2)CC1.CN(C)C(=O)c1ccc(B(O)O)cc1>>CC(C)OC(=O)N1CCC(COc2ccc(-c3ccc(C(=O)N(C)C)cc3)cc2)CC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US04533664,CCN1C(C(=O)OC)=C(O)c2ccccc2S1(=O)=O.Nc1cncc(Cl)n1>>CCN1C(C(=O)Nc2cncc(Cl)n2)=C(O)c2ccccc2S1(=O)=O,,Cc1ccccc1C,,,,test
US20020045777A1,BrCCCOC1CCCCO1.CN(C(=O)OC(C)(C)C)[C@@H]1CC[C@@H](C=C(Br)Br)CC1>>CN(C(=O)OC(C)(C)C)[C@@H]1CC[C@@H](C#CCCCOC2CCCCO2)CC1,,C1CCOC1,CN1CCCN(C)C1=O,[Li]CCCC,[Cl-].[NH4+],test
US20130274227A1,CSC(SC)=C(C#N)C#N.NN>>CSc1[nH]nc(N)c1C#N,,CCO,,O,,test
US20050267093A1,Br.Nc1ccc(-c2ccccc2)cc1>>Nc1ccc(-c2ccccc2)cc1Br,,CS(C)=O,,N,,test
US05334719,CC(OS(C)(=O)=O)c1ccc2ccccc2n1.COC(=O)C(C)(C)Cc1c(SC(C)(C)C)c2cc(O)ccc2n1Cc1ccc(Cl)cc1>>COC(=O)C(C)(C)Cc1c(SC(C)(C)C)c2cc(OC(C)c3ccc4ccccc4n3)ccc2n1Cc1ccc(Cl)cc1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04261888,CSCC[C@H](N)CO.C[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)O>>CSCC[C@H](N)CO.C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20050165063A1,CCCN(CCC)Cc1ccc(N)cc1.O=Cc1ccc(CN2C(=O)c3ccccc3C2=O)cc1>>CCCN(CCC)Cc1ccc(NCc2ccc(CN3C(=O)c4ccccc4C3=O)cc2)cc1,,CO,O,CC(=O)O,[BH3-]C#N.[Na+],test
US20120022059A1,O=C(O)c1cc(-c2cccc(Cl)c2)c(-c2cccc(Cl)c2)o1.O=C1CNCCN1>>O=C1CN(C(=O)c2cc(-c3cccc(Cl)c3)c(-c3cccc(Cl)c3)o2)CCN1,,Cc1ccccc1,,CCN(CC)CC,O=S(Cl)Cl,test
US20070129419A1,CC(C)(C)OC(=O)N1CC(C(=O)O)C(c2ccc(F)cc2)C1>>CC(C)(C)OC(=O)N1CC(CO)C(c2ccc(F)cc2)C1,,C1CCOC1,,,,test
US20160096827A1,N#Cc1cc(-c2ncnc(Nc3ccc(N4CCN(C5COC5)CC4)cc3)n2)ccc1O[C@H]1CCNCC1(F)F.O=C1N[C@H](C(=O)O)CO1>>N#Cc1cc(-c2ncnc(Nc3ccc(N4CCN(C5COC5)CC4)cc3)n2)ccc1O[C@H]1CCN(C(=O)[C@@H]2COC(=O)N2)CC1(F)F,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05679576,C=O.F.OC(C(F)(F)F)C(F)(F)F>>FCOC(C(F)(F)F)C(F)(F)F,,O=S(=O)(O)O,,,,test
US06632826B1,CC(C)(C)NC(=O)C1CCC(O)CC1CC1OC(C)(C)N(C(=O)OC(C)(C)C)C1Cc1ccccc1.CI>>COC1CCC(C(=O)NC(C)(C)C)C(CC2OC(C)(C)N(C(=O)OC(C)(C)C)C2Cc2ccccc2)C1,,CN(C)C=O,,[H-].[Na+],,test
US20030225007A1,NCCCCCCNc1nsc2nccn12.O=S(=O)(Cl)c1cccc2ccccc12>>O=S(=O)(NCCCCCCNc1nsc2nccn12)c1cccc2ccccc12,,c1ccncc1,,,,test
US20060148862A1,CCCCCCCNC(=O)N(C)c1nc(-c2ccc(C[C@H](OCC)C(=O)OC)cc2)n(C)n1>>CCCCCCCNC(=O)N(C)c1nc(-c2ccc(C[C@H](OCC)C(=O)O)cc2)n(C)n1,,C1CCOC1,,[Li+].[OH-],,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccccc23)cc1.Cc1cc2[nH]ncc2cc1N>>Cc1cc2[nH]ncc2cc1Nc1nc2ccccc2c2c[nH]nc12,C1COCCO1,CO,,Cl,,test
US20120094997A1,COC(=O)c1ccc2ccn(Cc3cccc(NC(=O)OC(C)(C)C)c3)c(=O)c2c1>>COC(=O)c1ccc2ccn(Cc3cccc(N)c3)c(=O)c2c1,,ClCCl,,C1COCCO1,Cl,test
US20080306053A1,N#Cc1cccnc1NC(=O)NC(=O)c1ccccc1>>Nc1nc(=O)[nH]c2ncccc12,,CCO,,[Na+].[OH-],,test
US20120208806A1,CC(C)NCCCn1c(Sc2cc3c(cc2I)OCO3)nc2c(N)ncnc21.OB(O)c1ccoc1>>CC(C)NCCCn1c(Sc2cc3c(cc2-c2ccoc2)OCO3)nc2c(N)ncnc21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,CN(C)C=O,O=C([O-])O.[Na+],test
US05496843,COC(=O)C(=O)Cc1c(CCCO)cc(Cl)cc1[N+](=O)[O-]>>COC(=O)c1cc2c(CCCO)cc(Cl)cc2[nH]1,,CC(C)=O,,O,,test
US20140163000A1,CI.COc1cc(NC(=O)OC(C)(C)C)ncc1I>>COc1cc(N(C)C(=O)OC(C)(C)C)ncc1I,,CN(C)C=O,,[H-].[Na+],,test
US20030232875A1,O=C1NC(=O)c2ccccc21.O[C@@H]1c2ccccc2C[C@H]1Br>>O=C1c2ccccc2C(=O)N1[C@@H]1Cc2ccccc2[C@H]1O,,CN(C)C=O,,[K],,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccccc23)cc1.Nc1ccc2c(c1)OCO2>>c1ccc2c(c1)nc(Nc1ccc3c(c1)OCO3)c1n[nH]cc12,C1COCCO1,CO,,Cl,,test
US20040157804A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2c3c(c(OC(c4ccccc4)c4ccccc4)c4ncccc24)C(=O)N(Cc2ccc(F)cc2)C3)CC1>>O=C1c2c(c(C(=O)N3CCNCC3)c3cccnc3c2O)CN1Cc1ccc(F)cc1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20040157838A1,O=P(Cl)(Cl)Cl.O=c1cc[nH]c2cc(-c3ccccc3Cl)nn12>>Clc1ccccc1-c1cc2nccc(Cl)n2n1,,CCOC(C)=O,Cc1ccccc1,CCN(CC)CC,O=C([O-])O.[Na+],test
US20110152240A1,Cc1c(Cl)nc2c(C=O)cnn2c1N(C(=O)OC(C)(C)C)C1CC1.N#Cc1cccnc1N1CCNCC1>>Cc1c(N2CCN(c3ncccc3C#N)CC2)nc2c(C=O)cnn2c1NC1CC1,,CC(C)O,,,,test
US04939253,C[C@H]1[C@H](NC(=O)OC(C)(C)C)C(=O)N1O.O=C(CCl)OC(c1ccccc1)c1ccccc1>>C[C@H]1[C@H](NC(=O)OC(C)(C)C)C(=O)N1OCC(=O)OC(c1ccccc1)c1ccccc1,,CN(C)C=O,,CCN(CC)CC,,test
US20160200719A1,COC(=O)c1ccc(CCNc2cnnc3ccc(C(c4ccc(Cl)cc4)c4ccc(Cl)cc4)cc23)cc1>>O=C(O)c1ccc(CCNc2cnnc3ccc(C(c4ccc(Cl)cc4)c4ccc(Cl)cc4)cc23)cc1,,CO,,[Na+].[OH-],,test
US20160229837A1,CCC1CN(C(=O)OC(C)(C)C)CCC1Nc1nc(Cl)ncc1Cl.CI>>CCC1CN(C(=O)OC(C)(C)C)CCC1N(C)c1nc(Cl)ncc1Cl,,C1CCOC1,,[H-].[Na+],,test
US20080233127A1,Clc1nc(N2CCOCC2)c2ncn(C3CCNCC3)c2n1.O=Cc1cccnc1>>Clc1nc(N2CCOCC2)c2ncn(C3CCN(Cc4cccnc4)CC3)c2n1,,C1CCOC1,ClCCl,O=C(O)C(F)(F)F,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100256188A1,N#Cc1ccc(Cl)c(N)c1>>NCc1ccc(Cl)c(N)c1,[Ni],CO,,N,,test
US20040082607A1,Cc1nnc(-c2ccc3c(=O)n(CC(C)C)c(CNC(=O)OC(C)(C)C)c(-c4ccccc4)c3c2)o1>>Cc1nnc(-c2ccc3c(=O)n(CC(C)C)c(CN)c(-c4ccccc4)c3c2)o1,,O=C([O-])O,[Na+],CCOC(C)=O,Cl,test
US20130317024A1,CC(C)I.COC(=O)c1cc[nH]c1>>COC(=O)c1ccn(C(C)C)c1,,CN(C)C=O,,[H-].[Na+],,test
US20130217680A1,CC1Cc2cc(CC3OCCO3)ccc2C(=O)O1>>CC1Cc2cc(CC=O)ccc2C(=O)O1,,C1COCCO1,,Cl,,test
US20080319188A1,CN(C)[C@@H]1CCNC1.O=C(Oc1ccccc1)N(C(=O)Oc1ccccc1)c1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ccn1>>CN(C)[C@@H]1CCN(C(=O)Nc2cc(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccn2)C1,,CN(C)C=O,,,,test
US20040006056A1,CCOC(=O)CC1(c2ccc(NC(C)=O)cc2)C(=O)c2ccccc2C1=O>>CCOC(=O)CC1(c2ccc(NC(C)=O)cc2)C(O)c2ccccc2C1O,,CCO,,CC(=O)O,[BH4-].[Na+],test
US20130296377A1,COc1cc(C)c2c(ccn2C(=O)OC(C)(C)C)c1C(O)c1nc2cc(C#N)ccc2o1>>COc1cc(C)c2[nH]ccc2c1C(O)c1nc2cc(C#N)ccc2o1,,CCOC(C)=O,CO,O=C([O-])[O-].[Cs+].[Cs+],,test
US20010027196A1,CSc1nc(N)nc(-c2ccco2)c1Br.O=S(=O)(c1ccccc1)N1OC1c1ccccc1>>CS(=O)c1nc(N)nc(-c2ccco2)c1Br,,ClCCl,,,,test
US20020193414A1,Nc1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1.O=CCCl>>O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(NCCCl)ccc1Cl,,CO,,Cl,[BH3-]C#N.[Na+],test
US20020193367A1,CCCN(C)c1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1C>>CCCN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1C,[Pd],,,,,test
US04536507,N#Cc1ccc2c(c1)Sc1ccc(N)cc1C=C2.O=N[O-]>>N#Cc1ccc2c(c1)Sc1ccc(O)cc1C=C2,,O,,O=S(=O)(O)O,,test
US20100113391A1,CCOC(=O)C(C)P(=O)(OCC)OCC.O=CCn1c(=O)c2cc(F)c(NC3CCCCC3)cc2n(C2CCCC2)c1=O>>CCOC(=O)/C(C)=C/Cn1c(=O)c2cc(F)c(NC3CCCCC3)cc2n(C2CCCC2)c1=O,,O,,CN(C)C=O,[H-].[Na+],test
US20120115811A1,CCn1nc(-c2ccncc2)cc1NC(=O)[C@@H](Cc1ccccc1)OC(C)=O>>CCn1nc(-c2ccncc2)cc1NC(=O)[C@H](O)Cc1ccccc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US05795887,CC(C)N(C(=O)CN1C(=O)C(N)N=C(c2ccccc2)c2ccccc21)c1ccccc1.Nc1cccc(-c2nn[nH]n2)c1.O=C(n1ccnc1)n1ccnc1>>CC(C)C(C(=O)Nc1ccccc1)N1C(=O)C(NC(=O)Nc2cccc(-c3nnn[nH]3)c2)N=C(c2ccccc2)c2ccccc21,,C1CCOC1,,Cl,,test
US20140309208A1,CCOc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O.Cc1ccc([C@H](N)C2(C)COC2)o1>>Cc1ccc([C@H](Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C2(C)COC2)o1,,CO,,,,test
US20040147611A1,CCOC(=O)/C=C(C)/C=C/C(F)=C(/CC)c1cc2c(cc1OCC)C(C)(C)CCC2(C)C>>CCOc1cc2c(cc1/C(CC)=C(F)\C=C\C(C)=C\C(=O)O)C(C)(C)CCC2(C)C,,CCO,,Cl,[K+].[OH-],test
US04354973,O=C(O)c1ccc(Cl)cc1C(=O)c1ccccc1>>O=C(O)c1ccc(Cl)cc1Cc1ccccc1,[Zn],[NH4+],[OH-],,,test
US20150119385A1,COCCOc1cc(NC(=O)N2CCCc3cc(CO[Si](C)(C)C(C)(C)C)c(C(OC)OC)nc32)ncc1C#N>>COCCOc1cc(NC(=O)N2CCCc3cc(CO)c(C=O)nc32)ncc1C#N,,C1CCOC1,O,Cl,O=C([O-])O.[Na+],test
US05442060,CCCCC[C@@H](CN)c1cccc2c1OCO2.CCOC(=O)c1cnn(-c2ccccc2)c1N.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCCCC[C@@H](CNC(=O)Nc1c(C(=O)OCC)cnn1-c1ccccc1)c1cccc2c1OCO2,,ClCCl,,CCN(CC)CC,,test
US20140256733A1,Clc1ccc2ncc(-c3cc4cccnc4s3)n2n1.N[C@H]1CC[C@H](O)CC1>>O[C@@H]1CC[C@@H](Nc2ccc3ncc(-c4cc5cccnc5s4)n3n2)CC1,,CS(C)=O,O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20020035263A1,CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)O.CC[Al](Cl)CC.COc1ccccc1C1CCNCC1.C[N+]1([O-])CCOCC1.On1nnc2ccccc21>>COc1ccccc1C1CCN(C[C@@H](Cc2ccccc2)NC(=O)C2(C)CCCCC2)CC1,,CCOC(C)=O,CN(C)C=O,,,test
US20140142298A1,Nc1ccc(CC(=O)NCC2CN(CC(=O)O)CCN(CC(=O)O)CCN2CC(=O)O)cc1.S=C(Cl)Cl>>O=C(O)CN1CCN(CC(=O)O)CC(CNC(=O)Cc2ccc(N=C=S)cc2)N(CC(=O)O)CC1,,ClCCl,O,,,test
US04877858,CC[C@H](C)CO.O=C(O)c1ccc(-c2ccc(O)cc2)cc1>>CCC(C)COC(=O)c1ccc(-c2ccc(O)cc2)cc1,,c1ccccc1,,O=S(=O)(O)O,,test
US20090270391A1,COc1cc(Oc2ccnc3cc(-c4nccn4C)sc23)ccc1N.S=C(Oc1ccccn1)Oc1ccccn1>>COc1cc(Oc2ccnc3cc(-c4nccn4C)sc23)ccc1N=C=S,,ClC(Cl)Cl,,O,,test
US20050209338A1,Nc1cccc(CCCCOCCCCCCBr)c1.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)Nc1cccc(CCCCOCCCCCCBr)c1,,ClCCl,,CO,,test
US20070141512A1,C=CC(=O)OC(C)CC1C2CC3CC(C2)CC1C3.Oc1ccc(S)cc1>>CC(CC1C2CC3CC(C2)CC1C3)OC(=O)CCSc1ccc(O)cc1,,CO,,CCN(CC)CC,CCOC(C)=O,test
US20040063714A1,C[Si](C)(C)CCOCn1c(COc2nn3c(-c4ccc(F)cc4F)nnc3cc2C2CCC2)nc2ccccc21>>Fc1ccc(-c2nnc3cc(C4CCC4)c(OCc4nc5ccccc5[nH]4)nn23)c(F)c1,,CCO,Cl,,,test
US20150072969A1,CCOC(=O)CC1(c2ccc(OCc3cccc(-c4c(C)cc(O)cc4C)c3)cc2)COC1.OCC1(CBr)COC1>>CCOC(=O)CC1(c2ccc(OCc3cccc(-c4c(C)cc(OCC5(CO)COC5)cc4C)c3)cc2)COC1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120316151A1,CCC(=O)Cl.O=c1[nH]nc(C[C@@H]2CCNC2)n1-c1ccc(Br)cc1F>>CCC(=O)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(Br)cc2F)C1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20100210671A1,CCCC1(c2ccc(F)cc2)c2cc(Cl)ccc2N(Cc2ccncc2)C(=O)N1CC(F)(F)F.O=C(OO)c1cccc(Cl)c1>>CCCC1(c2ccc(F)cc2)c2cc(Cl)ccc2N(Cc2cc[n+]([O-])cc2)C(=O)N1CC(F)(F)F,,ClCCl,,,,test
US20090233946A1,Nc1cc(Cl)ccc1C(=O)O.O=S(=O)(Cl)c1ccc(Cl)c(C(F)(F)F)c1>>O=C(O)c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1,,C1COCCO1,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US04727082,COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cc([N+](=O)[O-])ccc1OCCN.c1ccc(C2CO2)cc1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cc([N+](=O)[O-])ccc1OCCNCC(O)c1ccccc1,,CN(C)C=O,,,,test
US20130178478A1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1cc(Nc2cccc(C3CCC3)n2)c(C(N)=O)nn1>>NC(=O)c1nnc(N[C@@H]2CCCC[C@@H]2N)cc1Nc1cccc(C2CCC2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090099155A1,CC(O)c1ccccn1.O=C1CCC(=O)N1Br>>CC(Br)c1ccccn1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20160159752A1,CC(C)[C@H](c1ccc(Cl)cc1)[C@H](N=[N+]=[N-])C(=O)N1C(=O)OC[C@@H]1c1ccccc1.OO>>CC(C)[C@H](c1ccc(Cl)cc1)[C@H](N=[N+]=[N-])C(=O)O,,C1CCOC1,O,[Li+].[OH-],,test
US05681958,O=C(O)c1c2nc3ccc(Br)c(Cl)c3c-2[nH]c2ccccc12>>Clc1c(Br)ccc2nc3cc4ccccc4[nH]c-3c12,,c1ccc(Oc2ccccc2)cc1,,,,test
US20140315888A1,CN(C(=O)OC(C)(C)C)C1CN(c2nc3ncc([N+](=O)[O-])cc3nc2Cl)C1.NN>>CN(C(=O)OC(C)(C)C)C1CN(c2nc3ncc([N+](=O)[O-])cc3nc2NN)C1,,CCO,,O,,test
US20100311734A1,C[Si](C)(C)OC1(C#N)Cc2ccccc2Sc2ccc(F)cc21>>NCC1(O)Cc2ccccc2Sc2ccc(F)cc21,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20030171370A1,O=C(O)c1ccc(CO)cc1.O=CO>>O=COCc1ccc(C(=O)O)cc1,,O,,CC(=O)OC(C)=O,,test
US04588718,O=C(O)CS.OCCCCCCCl>>O=C(O)CSCCCCCCO,,[Na+],[OH-],,,test
US20070208062A1,Brc1ccc(C2=NO[C@H](COCCN3CCOCC3)C2)nc1.CC1(C)OB(c2ccc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)OC1(C)C>>O=C1O[C@H](Cn2ccnn2)CN1c1ccc(-c2ccc(C3=NO[C@H](COCCN4CCOCC4)C3)nc2)c(F)c1,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US06337331B1,Cn1ncnc1CO.O=c1[nH]c2c(-c3ccccc3F)nnn2cc1-c1ccccc1>>Cn1ncnc1COc1nc2c(-c3ccccc3F)nnn2cc1-c1ccccc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090137582A1,CCOC(=O)c1cnn(-c2cccc(F)c2)c1NC(C)=O.CI>>CCOC(=O)c1cnn(-c2cccc(F)c2)c1N(C)C(C)=O,,C1CCOC1,CN(C)C=O,[H-].[Na+],[Cl-].[NH4+],test
US20020016506A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N#Cc1ccc(N)c([N+](=O)[O-])c1>>CC(C)(C)OC(=O)Nc1ccc(C#N)cc1[N+](=O)[O-],,C1CCOC1,,[H-].[Na+],,test
US20100010053A1,CCOC(=O)CCc1cc2cc(-c3noc(-c4cnc(OC(C)C)c(Cl)c4)n3)ccc2[nH]1.COC(=O)OC>>COC(=O)CCc1cc2cc(-c3noc(-c4cnc(OC(C)C)c(Cl)c4)n3)ccc2n1C,,CCOC(C)=O,CN(C)C=O,C1CN2CCN1CC2,,test
US20130032764A1,O=C1CCC(=O)N1Br.c1ccc(-c2ncc(-c3c4ccccc4cc4ccccc34)cn2)nc1>>Brc1c2ccccc2c(-c2cnc(-c3ccccn3)nc2)c2ccccc12,,ClC(Cl)Cl,,O,,test
US20100113801A1,CC[Si](Cl)(CC)CC.O=C1CC[C@@H](Cc2ccc(-c3ccccc3)cc2)N1>>CC[Si](CC)(CC)N1C(=O)CC[C@H]1Cc1ccc(-c2ccccc2)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20030013720A1,CC(C)COC(=O)NCC1(c2ccc(I)cc2)CCNCC1.O=CC1CC1>>CC(C)COC(=O)NCC1(c2ccc(I)cc2)CCN(CC2CC2)CC1,,CCOC(C)=O,ClCCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04125729,COC(=O)C(Oc1ccccc1)c1ccc(Oc2ccc(Cl)cc2)cc1>>O=C(O)C(Oc1ccccc1)c1ccc(Oc2ccc(Cl)cc2)cc1,,CO,,[K+].[OH-],,test
US20110039893A1,CNc1ccccc1N.O.c1ccncc1>>Cn1c(=O)[nH]c2ccccc21,,O,,C1CCOC1,,test
US05026836,NSc1nc(N)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O.O=C(OO)c1cccc(Cl)c1>>Nc1nc(S(N)=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3O)c2n1,,CCO,O,,,test
US20100113514A1,CC(C)(C)OC(=O)c1ccc(CBr)cc1.O=C1CCc2ccc(O)cc2N1>>CC(C)(C)OC(=O)c1ccc(COc2ccc3c(c2)NC(=O)CC3)cc1,,CCOCC,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20070225201A1,CCOC(=O)C1(C)CC12CCCC(C)(C)C2>>CC1(C)CCCC2(C1)CC2(C)C(=O)O,,CCO,O,[Na+].[OH-],,test
US20150218129A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(C=CC(=O)N3CCOCC3)cc2)CC1>>O=C(C=Cc1ccc(OC2CCNCC2)cc1)N1CCOCC1,,ClCCl,,O,O=C(O)C(F)(F)F,test
US04877444,Fc1ccc(-n2nc3c(c2Cl)CCCC3)c(F)c1.O=[N+]([O-])O>>O=[N+]([O-])c1cc(-n2nc3c(c2Cl)CCCC3)c(F)cc1F,,O=S(=O)(O)O,,,,test
US20080132497A1,O=C1c2ccccc2C(=O)N1CC(O)COc1ccc2c(c1)sc1ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c12>>NCC(O)COc1ccc2c(c1)sc1ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c12,,CCO,,,,test
US20130231333A1,CC/C(=C(/c1ccc(/C=C/C(N)=N/O)cc1)c1ccc2c(cnn2C2CCCCO2)c1)c1ccccc1.S=C(n1ccnc1)n1ccnc1>>CC/C(=C(/c1ccc(/C=C/c2noc(=S)[nH]2)cc1)c1ccc2c(cnn2C2CCCCO2)c1)c1ccccc1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20150011528A1,CCC(C(=O)[O-])n1c(=NC(=O)c2ccc(C)cc2)sc2cc(OCc3ccccc3)ccc21>>CCC(C(=O)O)n1c(=NC(=O)c2ccc(C)cc2)sc2cc(OCc3ccccc3)ccc21,,CO,,C1CCOC1,[Na+].[OH-],test
US20080161297A1,O=c1[nH]cnc2cc([N+](=O)[O-])c(Cl)cc12>>Nc1cc2nc[nH]c(=O)c2cc1Cl,[Fe],CO,O,[Cl-].[NH4+],,test
US20110135650A1,N#Cc1ccc(NC(=O)[C@H](O)[C@H]2OCCN(c3ccc(I)cc3)C2=O)cc1.OB(O)c1cccs1>>N#Cc1ccc(NC(=O)[C@H](O)[C@H]2OCCN(c3ccc(-c4cccs4)cc3)C2=O)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160075711A1,CC(=O)OC(C)=O.O=C(CC1c2c(F)cccc2-c2cncn21)C1CCC(O)CC1>>CC(=O)OC1CCC(C(=O)CC2c3c(F)cccc3-c3cncn32)CC1,CN(C)c1ccncc1,ClCCl,,,,test
US20140275711A1,C[Si](C)(C)N[Si](C)(C)C.O=c1[nH]c2c(c(=O)[nH]1)CCC2>>C[Si](C)(C)Oc1nc2c(c(O[Si](C)(C)C)n1)CCC2,,Cc1ccccc1,,O=S(=O)(O)O,,test
US20100160369A1,CC(C)(C)[Si](C)(C)OCC(F)(F)COc1cc(Cl)c(-c2noc(-c3cn4cc(C(F)(F)F)cc(Cl)c4n3)n2)cc1Cl>>OCC(F)(F)COc1cc(Cl)c(-c2noc(-c3cn4cc(C(F)(F)F)cc(Cl)c4n3)n2)cc1Cl,,O,O=C(O)C(F)(F)F,,,test
US05631286,COc1ccc(C=O)cc1O.ClCC1CC1>>COc1ccc(C=O)cc1OCC1CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150045348A1,CC1CN(Cc2ccccc2)CC1c1nn2cncc2c(=O)[nH]1.II>>CC1CN(Cc2ccccc2)CC1c1nn2c(I)ncc2c(=O)[nH]1,,C1CCOC1,,[Li]CCCC,,test
US20120015941A1,CNOC.O=C(NCc1cccc(F)c1)Nc1nc(CCl)cs1>>CON(C)Cc1csc(NC(=O)NCc2cccc(F)c2)n1,,O,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20010039348A1,CC(C)(C)OC(=O)Nc1ccc(N)c(Cl)c1.ClCCl.O.OCCN1CCCCC1>>CC(C)(C)OC(=O)Nc1ccc(NC(=O)OCCN2CCCCC2)c(Cl)c1,,ClCCl,,C1CCOC1,,test
US20120184546A1,Nc1nc2c3ccccc3nc(Cc3cccc([N+](=O)[O-])c3)n2n1>>Nc1cccc(Cc2nc3ccccc3c3nc(N)nn23)c1,[Pd],CN(C)C=O,,,,test
US04810722,CCOC1CCC(=O)N1.O=S(=O)(Cl)C=Cc1ccccc1>>CCOC1CCC(=O)N1S(=O)(=O)C=Cc1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US20080207654A1,CCCc1nc(CC)n(-c2ccc(OC(C)C)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCc1nc(CC)n(-c2ccc(OC(C)C)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,O,,CS(C)=O,[Cl-].[Na+],test
US20060052599A1,CCOC(=O)/C=C/c1ccc(N[C@@H]2CCN(C(=O)c3ccc(Cl)cc3)C2)cc1>>O=C(O)/C=C/c1ccc(N[C@@H]2CCN(C(=O)c3ccc(Cl)cc3)C2)cc1,,C1COCCO1,O,[Na+].[OH-],,test
US20020198195A1,CC(=O)c1ccncc1.NC=O>>CC(NC=O)c1ccncc1,,O,O=CO,[Na+].[OH-],,test
US20050038016A1,CC(C)(C)[Si](C)(C)OCCOc1cccc(C=O)c1.CN>>CN=Cc1cccc(OCCO[Si](C)(C)C(C)(C)C)c1,,CCO,,,,test
US20040198736A1,CCCCC([Sn])=C(CCCC)CCCC.CCOC(=O)Cc1ccc(Cl)c(Oc2cc(Br)cc(C#N)c2)c1F.Cc1ccccc1>>C=Cc1cc(C#N)cc(Oc2c(Cl)ccc(CC(=O)OCC)c2F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,,,test
US20080045497A1,COC(=O)CNc1ccc(Br)cc1.O=C(Cl)C=Cc1ccccc1>>COC(=O)CN(C(=O)/C=C/c1ccccc1)c1ccc(Br)cc1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20060035956A1,CCOC(=O)Cn1ccc2ccc(N)cc21.O=C(O)CCC#Cc1cccc(OC(F)(F)F)c1>>CCOC(=O)Cn1ccc2ccc(NC(=O)CCC#Cc3cccc(OC(F)(F)F)c3)cc21,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20090209529A1,CC(=O)c1cccc(Br)c1.CC(C)Oc1ccc(Br)cc1>>C=C(c1ccc(OC(C)C)cc1)c1cccc(Br)c1,,C1CCOC1,,Cl,[Li]CCCC,test
US20150361059A1,COc1ccc2cc(Br)ccc2c1CCl.Cc1ccc2c(c1)OC[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)N2>>COc1ccc2cc(Br)ccc2c1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)COc2cc(C)ccc21,,CCOC(C)=O,CN(C)C=O,[I-].[Na+],O=C([O-])[O-].[Cs+].[Cs+],test
US20120071503A1,Cc1ccc(C(=O)O)cc1I.O=c1c2ccc(OCc3cccc(B(O)O)c3)cc2sn1C1CCCC1>>Cc1ccc(C(=O)O)cc1-c1cccc(COc2ccc3c(=O)n(C4CCCC4)sc3c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,N#N,O=C([O-])[O-].[Na+].[Na+],test
US20120258946A1,CC(C)(C)c1cc(CN)n(-c2cccc(Cl)c2)n1.O=C(Nc1ccc(C(O)(CO)CO)cc1)Oc1ccccc1>>CC(C)(C)c1cc(CNC(=O)Nc2ccc(C(O)(CO)CO)cc2)n(-c2cccc(Cl)c2)n1,,CC#N,,,,test
US20100137299A1,BrCCBr.O=C1C(c2cc3c(cc2O)OCC3)c2ccccc2N1C(c1ccccc1)c1ccccc1>>O=C1N(C(c2ccccc2)c2ccccc2)c2ccccc2C12CCOc1cc3c(cc12)CCO3,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080058332A1,CC(C)(C)OC(=O)NCC(=O)O.Nc1cccc(-c2nc(-c3cccc(CO)c3)cc(N3CCOCC3)n2)c1>>NCC(=O)Nc1cccc(-c2nc(-c3cccc(CO)c3)cc(N3CCOCC3)n2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04189499,C=CCOc1ccc(CC(=O)O)cc1Cl.CCO.NCCCC[C@H](N)C(=O)O.O>>NCCCC[C@H](N)C(=O)O.O=C(O)O.O=C=O,,CCO,O,,,test
US20040254371A1,CCCC[Sn](CCCC)(CCCC)c1ccco1.O=S1(=O)N=C2CCCN2c2ccc(Oc3cccc(Br)c3)cc21>>O=S1(=O)N=C2CCCN2c2ccc(Oc3cccc(-c4ccco4)c3)cc21,,Cc1ccccc1,,,,test
US05721234,CC(=O)Nc1ccc(Br)c2c1CC(OC(C)=O)CC2.O=[N+]([O-])O>>CC(=O)Nc1c([N+](=O)[O-])cc(Br)c2c1CC(OC(C)=O)CC2,,O=C(O)C(F)(F)F,,,,test
US20110118488A1,C=C1C[C@H]2[C@@H]3CC[C@H](OC(C)=O)[C@@]3(C)CC[C@@H]2[C@@]2(C)C=CC(=O)C=C12>>C=C1C[C@H]2[C@@H]3CC[C@H](O)[C@@]3(C)CC[C@@H]2[C@@]2(C)C=CC(=O)C=C12,,CO,,CC(=O)O,[Na+].[OH-],test
US20090170921A1,CC(C)c1ccc(C(=O)O)cc1.COc1ccc(Br)c(N)c1N>>COc1ccc(Br)c(N)c1NC(=O)c1ccc(C(C)C)cc1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20150299189A1,COC(=O)c1cc(C2CC2)cnc1N(C(=O)C(F)(F)F)c1ccc2c(ccn2C(=O)OC(C)(C)C)c1>>COC(=O)c1cc(C2CC2)cnc1N(C(=O)C(F)(F)F)c1ccc2[nH]ccc2c1,,CC(=O)N(C)C,,,,test
US05668137,COc1nc(C)cnc1N.O=S(=O)(Cl)c1ccccc1I>>COc1nc(C)cnc1NS(=O)(=O)c1ccccc1I,,c1ccncc1,,,,test
US20150038488A1,Brc1cc2ccncc2s1.C[C@@H](Oc1nc(B2OC(C)(C)C(C)(C)O2)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1>>C[C@@H](Oc1nc(C2Cc3ccncc3S2)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,ClCCl,N#N,O=C([O-])[O-].[Na+].[Na+],test
US20030233015A1,CC(C)S(=O)(=O)Cl.C[C@@H](CN)c1ccc([N+](=O)[O-])cc1>>CC(C)S(=O)(=O)NC[C@H](C)c1ccc([N+](=O)[O-])cc1,,ClCCl,,CCN(CC)CC,,test
US20150056305A1,CC(C)(C)OC(=O)/N=C(/NC(=O)OC(C)(C)C)n1cccn1.CC(C)(C)OC(=O)N[C@H](CCCCN)C(=O)O>>CC(C)(C)OC(=O)N=C(NCCCC[C@@H](NC(=O)OC(C)(C)C)C(=O)O)NC(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US05147645,CC(C)c1cccc(CO)c1Cl.O=S(Cl)Cl>>CC(C)c1cccc(CCl)c1Cl,,ClC(Cl)(Cl)Cl,,,,test
US20070244125A1,CC(C)N1CCNCC1.O=C(O)c1ccc2c(c1)cc(C(=O)N1CCOCC1)n2CC(F)(F)F>>CC(C)N1CCN(C(=O)c2ccc3c(c2)cc(C(=O)N2CCOCC2)n3CC(F)(F)F)CC1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20100137305A1,NC(N)=S.O=C(Nc1ccc(I)cc1F)C1CC1>>O=C(Nc1ccc(S)cc1F)C1CC1,[Ni],CN1CCCC1=O,,,,test
US20080114006A1,CSc1ncc2cc(Br)c(=O)n(C(C)C)c2n1.O=[N+]([O-])c1cc(B(O)O)ccc1F>>CSc1ncc2cc(-c3ccc(F)c([N+](=O)[O-])c3)c(=O)n(C(C)C)c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US06037474,CC(C)C(C)(N)C(N)=O.CCCCC=O>>CCCCC1NC(=O)C(C)(CCC)N1,,O,,CO,,test
US20050054627A1,CCC[C@@H]1C[C@H](N(C)C(C)C)CC[C@@H]1N1CC[C@H](N)C1=O.CCNC(=O)Nc1ccc(C(F)(F)F)cc1C(=O)O>>CCC[C@@H]1C[C@H](N(C)C(C)C)CC[C@@H]1N1CC[C@H](NC(=O)c2cc(C(F)(F)F)ccc2NC(=O)NCC)C1=O,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060194811A1,Clc1ncc(I)c(Cl)n1.NCc1ccc(F)cc1F>>Fc1ccc(Cc2nc(Cl)ncc2I)c(F)c1,,CCO,,O=C([O-])O.[Na+],,test
US20030236212A1,CC(C)(CCCCBr)COC1CCCCO1.[C-]#N>>CC(C)(CCCCC#N)COC1CCCCO1,,CS(C)=O,,O,,test
US20120214767A1,C=Cc1ccc2c(c1)CCCC2=O.O=C(F)c1noc(-c2ccccc2)c1C(F)(F)F>>C=Cc1ccc2c(c1)CCC(C(=O)c1noc(-c3ccccc3)c1C(F)(F)F)C2=O,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20160272617A1,Cc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1.Cl>>Cc1cc(C(=O)N2CCNCC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1.Cl,,C1COCCO1,,,,test
US20150291595A1,COc1ccc(S(=O)(=O)Nc2cccc(-c3c(N)ncnc3N[C@@H](C)c3nn4cccc4c(=O)n3-c3ccccc3)c2)cc1>>C[C@H](Nc1ncnc(N)c1-c1cccc(NS(=O)(=O)c2ccc(O)cc2)c1)c1nn2cccc2c(=O)n1-c1ccccc1,,ClCCl,,BrB(Br)Br,,test
US20100311732A1,CCOC(=O)c1ncn2c1CN(C(=O)C[C@@H](Cc1cc(F)c(F)cc1F)NC(=O)OC(C)(C)C)Cc1ccccc1-2.O=C(O)C(F)(F)F>>CCOC(=O)c1ncn2c1CN(C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F)Cc1ccccc1-2.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20040087601A1,CCCC[Sn](Cl)(CCCC)CCCC.Fc1ccc2occc2c1>>CCCC[Sn](CCCC)(CCCC)c1cc2cc(F)ccc2o1,,C1CCOC1,,O,[Li]CCCC,test
US20020055631A1,CC(C)(C)OC(=O)NNc1ccc(S(N)(=O)=O)cc1[N+](=O)[O-].O=C1CCCc2ccccc21>>NS(=O)(=O)c1ccc(N/N=C2\CCCc3ccccc32)c([N+](=O)[O-])c1,,ClCCl,O=C(O)C(F)(F)F,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US04861795,CCOC(=O)c1cc2cccc(OCc3ccccc3)c2cc1OCCN1CCCCC1.Cl>>CCOC(=O)c1cc2cccc(O)c2cc1OCCN1CCCCC1.Cl,[Pd],CCO,,,,test
US20050065340A1,COCOc1cc(-c2nc3ccccc3o2)ccc1C.O=C1CCC(=O)N1Br>>COCOc1cc(-c2nc3ccccc3o2)ccc1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20090318441A1,O=[N+]([O-])c1ccc(N2CCC(O)CC2)cc1>>O=C1CCN(c2ccc([N+](=O)[O-])cc2)CC1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20150266878A1,COCC(=O)NC[C@H](Nc1cncc(-c2ccc3[nH]nc(F)c3c2)c1)c1ccccc1>>COCCNC[C@H](Nc1cncc(-c2ccc3[nH]nc(F)c3c2)c1)c1ccccc1,,C1CCOC1,,,,test
US20100298324A1,COC(=O)c1ccc(C(=O)NCc2ccc(Cl)cc2)cc1N=C=S.Nc1cccnn1>>O=C(NCc1ccc(Cl)cc1)c1ccc2c(=O)n(-c3cccnn3)c(=S)[nH]c2c1,,CS(C)=O,,,,test
US20060106037A1,CC(O)C(CCCc1ccccc1)n1cnc(C(N)=O)c1N.CCOC(=O)Cc1ccc(OC(F)F)c(OC)c1>>COc1cc(Cc2nc3c(ncn3C(CCCc3ccccc3)C(C)O)c(=O)[nH]2)ccc1OC(F)F,,CCO,,[Na],,test
US20160068531A1,CC(C)(C)[Si](C)(C)OCc1cc2cc(Cl)cnc2n1CCC1CS(=O)(=O)C1>>O=S1(=O)CC(CCn2c(CO)cc3cc(Cl)cnc32)C1,,CCO,,Cl,O=C([O-])O.[Na+],test
US20140148433A1,Nc1nc(-c2nn(Cc3ccccc3F)c3ncccc23)ccc1[N+](=O)[O-]>>Nc1ccc(-c2nn(Cc3ccccc3F)c3ncccc23)nc1N,[Pd],c1ccncc1,,,,test
US20080275097A1,N#Cc1cc(Cl)cc(Oc2c(Cl)ccc3c2nnn3CC(=O)O)c1.Nc1ccncc1C(F)(F)F>>N#Cc1cc(Cl)cc(Oc2c(Cl)ccc3c2nnn3CC(=O)Nc2ccncc2C(F)(F)F)c1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20160214972A1,CC(C)(C)OC(=O)COCCCOCCCCCOCc1ccccc1>>CC(C)(C)OC(=O)COCCCOCCCCCO,[Pd],CO,,CC(=O)O,[H][H],test
US20080287535A1,COc1ccc(-c2ccccc2)cc1N=NC(=O)OC(C)C.O=C(OO)c1cccc(Cl)c1>>COc1ccc(-c2ccccc2)cc1[N+]([O-])=NC(=O)OC(C)C,,ClCCl,,,,test
US20140350002A1,Cn1c(=O)n(CC(C)(C)C)c2ccc(C3=CC4CN(C(=O)OC(C)(C)C)CC4C3)nc21>>Cn1c(=O)n(CC(C)(C)C)c2ccc(C3=CC4CNCC4C3)nc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100331328A1,CC(C)(C)OC(=O)n1ccc2cc(Cl)ncc21.N#Cc1cnc(N)cn1>>N#Cc1cnc(Nc2cc3cc[nH]c3cn2)cn1,,C1COCCO1,,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20100331372A1,CCc1cc(-c2noc(-c3cc(C)c(CC(C)C)cn3)n2)cc(C)c1OC[C@@H](O)CNC.COC(=O)CCN>>CCc1cc(-c2noc(-c3cc(C)c(CC(C)C)cn3)n2)cc(C)c1OC[C@@H](O)CNCCC(=O)OC,,CO,,CCN(CC)CC,Cl,test
US05013842,COC1O[C@@H]2CCN[C@H]1[C@H]2OCc1ccccc1.O=C(Cl)OCc1ccccc1>>COC1O[C@@H]2CCN(C(=O)OCc3ccccc3)[C@H]1[C@H]2OCc1ccccc1,,CCOCC,,O=C([O-])O.[Na+],,test
US20110092497A1,CC(C)(C)OC(=O)N(c1ccc(N2CCOCC2)cc1)c1ncc(-c2cc(F)nc(C(F)(F)F)c2)n2ccnc12.O>>O=c1cc(-c2cnc(Nc3ccc(N4CCOCC4)cc3)c3nccn23)cc(C(F)(F)F)[nH]1,,C1CCOC1,O,Cl,CC(C)(C)[O-].[K+],test
US05595989,BrCCCOC1CCCCO1.N#CC1c2ccccc2CCc2ccccc21>>N#CC1(CCCOC2CCCCO2)c2ccccc2CCc2ccccc21,,Cc1ccccc1,,[H-].[Na+],,test
US20100152166A1,COC(=O)c1cn(C)c2cc(N3CCC(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)CC3)ccc12>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COC1CCN(c2ccc3c(C(=O)O)cn(C)c3c2)CC1,,C1COCCO1,,[Li+].[OH-],,test
US20120220565A1,COC(=O)[C@]12C/C(=C/O)C(=O)C=C1CCN(C(=O)OC(C)(C)C)C2.NNc1ccc(F)cc1>>COC(=O)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(C(=O)OC(C)(C)C)C2,,CC(=O)O,,Cl,CC(=O)[O-].[Na+],test
US05091523,CC(=O)N[C@]1(O)[C@H](S)O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.CS(SCCN)=C(O)O.Cl>>CC(=O)CC(=O)CC(=O)O.Cl,,CO,,,,test
US20070004774A1,COC(=O)Cl.O=C(N1c2ccc(C(F)(F)F)cc2C(NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1CCOCc1ccccc1)C(F)(F)F>>COC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CC(CCOCc2ccccc2)N(C(=O)C(F)(F)F)c2ccc(C(F)(F)F)cc21,,ClCCl,,c1ccncc1,,test
US20110112151A1,Nc1nnc(S)s1.O=C(CBr)C12CC3CC(CC(C3)C1)C2>>Nc1nnc(SCC(=O)C23CC4CC(CC(C4)C2)C3)s1,,CC#N,,CCN(CC)CC,,test
US20020086891A1,COc1cccc(F)c1.O=C(Cl)c1ccc(C(F)(F)F)cc1F>>COc1ccc(C(=O)c2ccc(C(F)(F)F)cc2)c(F)c1,,O=[N+]([O-])c1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20090105211A1,Cc1ccc(Br)cc1N.O=C(Cl)c1ccc(Nc2nc(-c3ccccc3)c3ccccc3n2)cc1>>Cc1ccc(Br)cc1NC(=O)c1ccc(Nc2nc(-c3ccccc3)c3ccccc3n2)cc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20100249163A1,COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(O)c2ccnc(OCc3ccccc3)c2)C2CC2)cc(OCCOC)c1>>COCCCc1cc(CN(C(=O)C2CNCCC2(O)c2ccnc(OCc3ccccc3)c2)C2CC2)cc(OCCOC)c1,,ClCCl,,Cl,,test
US20060069256A1,COc1ccc2c(c1)c(CC(=O)NN1CCN(C(=O)OC(C)(C)C)CC1)c(C)n2C(=O)c1ccc(Cl)cc1>>COc1ccc2c(c1)c(CC(=O)NN1CCNCC1)c(C)n2C(=O)c1ccc(Cl)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100152451A1,O=C1CCN(C(=O)OCc2ccccc2)c2ccccc21>>O=C(OCc1ccccc1)N1CC[C@H](O)c2ccccc21,,ClCCl,,CO,,test
US20100152190A1,CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccn(CC(=O)OC(C)(C)C)n2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F>>CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2ccn(CC(=O)O)n2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F,,O,,O=S(=O)(O)O,,test
US20080119442A1,COC(=O)c1ccc2c(Br)c(N(CC=CCl)C(=O)OC(C)(C)C)ccc2c1>>COC(=O)c1ccc2c3c(ccc2c1)N(C(=O)OC(C)(C)C)CC3CCl,,c1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,CCCC[SnH](CCCC)CCCC,test
US20050197367A1,COC(=O)Cc1ccc(C#N)c2ccccc12>>N#Cc1ccc(CC(=O)O)c2ccccc12,,CO,,[Li+].[OH-],,test
US04734416,CCOC(=O)CBr.O=C1CCc2c(cccc2OCCCN2CCNCC2)N1>>CC(=O)OCCN1CCN(CCCOc2cccc3c2CCC(=O)N3)CC1,,CN(C)C=O,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20050176775A1,Cc1ccn(C(=O)OC(C)(C)C)n1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)n1ccc(CBr)n1,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US05082856,CCCCCCCCCCCCCCc1ccc(C(=O)OCC)[nH]1>>CCCCCCCCCCCCCCc1ccc(C(=O)O)[nH]1,,CCO,,[Na+].[OH-],,test
US20070093526A1,CC(C)CCN(Cc1cc2ccccc2o1)C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)CCN(Cc1cc2ccccc2o1)C1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080207703A1,COCCOCc1csc(NC(=O)OC(C)(C)C)n1.O=C(Cl)Oc1ccccc1>>COCCOCc1csc(NC(=O)Oc2ccccc2)n1,CN(C)c1ccncc1,C1CCOC1,c1ccncc1,O,,test
US20130252941A1,O=P(Br)(Br)Br.[O-][n+]1ccc2nn(-c3c(F)cccc3Cl)cc2c1>>Fc1cccc(Cl)c1-n1cc2c(Br)nccc2n1,,ClCCCl,ClCCl,,,test
US20010014691A1,CN1CCC(O)CC1.Oc1cccnc1>>CN1CCC(Oc2cccnc2)CC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05109000,CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C(CC(C)C)C(CC(=O)NCC(=O)O)SC(C)=O>>CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C(CC(C)C)C(S)CC(=O)NCC(=O)O,,CO,,N,,test
US05032594,CCCCn1c(=O)n(Cc2ccccc2)c(=O)c2c3n(nc21)CCN3>>CCCCn1c(=O)[nH]c(=O)c2c3n(nc21)CCN3,,CO,,BrB(Br)Br,,test
US20140038969A1,CC(C)(C)[S@](N)=O.O=Cc1cccc(Br)c1>>CC(C)(C)[S@@](=O)/N=C/c1cccc(Br)c1,,ClCCl,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05322954,COC(=O)C1=C(C(=O)OC)CC(Cl)=CC1.F.O=C1CCC(=O)N1Cl>>COC(=O)C1=C(C(=O)OC)CC(F)(Cl)C(Cl)C1,,ClCCl,,c1ccncc1,,test
US03962277,C/C(=N\[Si](C)(C)C)O[Si](C)(C)C.CC1(C)CC(=O)NC(=O)C1>>CC1(C)CC(=O)N([Si](C)(C)C)C(=O)C1,,CC#N,,,,test
US20070179143A1,COC(=O)c1cccc(CC=O)c1>>COC(=O)c1cccc(CCO)c1,,CCO,,[BH4-].[Na+],,test
US05849759,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1nc2cc(O)c(O)cc2[nH]1>>Cc1nc2cc(O)c(O)cc2n1C(=O)OC(C)(C)C,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20130072555A1,CC1(C)OB(C(Cl)Cl)OC1(C)C.CCOC(=O)C[C@H](C)C=O>>CCOC(=O)C[C@H](C)/C=C/B1OC(C)(C)C(C)(C)O1,,C1CCOC1,,[I-].[Li+],,test
US20140364410A1,CC(C)(Br)C=O.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(C(C)(C)C=O)CC1,,CCOCC,,,,test
US20110172240A1,CC(C)(C)OC(=O)[C@@H](CCCCN)C(=O)OCC[Si](C)(C)C.COC(=O)/C=C/C(=O)[O-]>>COC(=O)/C=C/C(=O)NCCCC[C@@H](C(=O)OCC[Si](C)(C)C)C(=O)OC(C)(C)C,,CC#N,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020151535A1,CC(C)(C)OC(=O)C[C@@H](CCCC1CCCCC1)c1nc(NS(=O)(=O)CCCCl)no1>>O=C(O)C[C@@H](CCCC1CCCCC1)c1nc(N2CCCS2(=O)=O)no1,,CO,,[Na],,test
US20150336986A1,BrBr.CCn1c(C)c(C(=O)c2ccccc2)c(=O)n(CC)c1=O>>CCn1c(CBr)c(C(=O)c2ccccc2)c(=O)n(CC)c1=O,,ClC(Cl)Cl,,,,test
US20130310277A1,CCC(N)C(=O)OC.O=C(O)CCC(=O)c1ccc2c(c1)OCCO2>>CCC(N)C(=O)O.O=C(O)CCC(=O)c1ccc2c(c1)OCCO2,,C1CCOC1,,O,[K+].[OH-],test
US20160052930A1,CCOC(=O)c1ncc([N+](=O)[O-])cc1C>>CCOC(=O)c1ncc(N)cc1C,[Pd],CCO,,,,test
US20030114508A1,BrCc1ccccc1.Cc1nc2c(n1C(C)C)C(=O)c1ccccc1C2=O>>Cc1n(Cc2ccccc2)c2c([n+]1C(C)C)C(=O)c1ccccc1C2=O.[Br-],,CC#N,,,,test
US05922751,BrC1CCCC1.COc1ccc(-c2nc(C(N)=O)c[nH]2)cc1O>>COc1ccc(-c2nc(C(N)=O)c[nH]2)cc1OC1CCCC1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130131018A1,CCOc1cccc(CNCC(OCC)OCC)c1O.COc1c(Cl)cc(C=O)cc1Cl.Cl>>CCOc1ccc2c(Cc3cc(Cl)c(OC)c(Cl)c3)cncc2c1O.Cl,,CCO,,CO,,test
US20150057271A1,COc1cc(C(F)(F)F)ccc1N1C(=O)COc2cc([N+](=O)[O-])ccc21>>COc1cc(C(F)(F)F)ccc1N1C(=O)COc2cc(N)ccc21,[Fe],C1CCOC1,,CC(=O)O,,test
US20130281433A1,CC(C)N1CCN(C(=O)OC(C)(C)C)[C@H](C)C1>>CC(C)N1CCN[C@H](C)C1,,C1COCCO1,,Cl,,test
US20090197898A1,CON(C)C(=O)c1ccccc1.Cc1ccncc1>>O=C(Cc1ccncc1)c1ccccc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20120277224A1,CCOC(=O)CC(=O)c1ccc2oc(C)cc2c1.Nc1n[nH]c(N)c1-c1ccccn1>>Cc1cc2cc(-c3cc(=O)n4nc(N)c(-c5ccccn5)c4[nH]3)ccc2o1,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120225854A1,CC(C)NC[C@H]1CN(S(=O)(=O)c2cccs2)CCN1c1ccc(C(C)(O)C(F)(F)F)cc1.CS(=O)(=O)Cl>>CC(C)N(C[C@H]1CN(S(=O)(=O)c2cccs2)CCN1c1ccc(C(C)(O)C(F)(F)F)cc1)S(C)(=O)=O,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20130225577A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1cnc2cc[nH]c2c1>>CC(C)(C)OC(=O)n1ccc2ncccc21,CN(C)c1ccncc1,ClCCl,,,,test
US20040082611A1,Cc1cc(-c2cnc(N3CCN(C(=O)OC(C)(C)C)CC3)s2)ccn1.Cl>>Cc1cc(-c2cnc(N3CCNCC3)s2)ccn1.Cl,,CO,,,,test
US20060025383A1,C1COCCN1.COc1ccc(C)cc1OCCCBr>>COc1ccc(C)cc1OCCCN1CCOCC1,,C1CCOC1,CCOCC,,,test
US04200641,ClC(c1ccccc1)c1ccccn1.O=c1[nH]c2ccccc2n1CCCN1CCNCC1>>O=c1[nH]c2ccccc2n1CCCN1CCN(C(c2ccccc2)c2ccccn2)CC1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20090286778A1,CC(C)(C)OC(=O)Nc1cccc(N)c1.CS(=O)(=O)OCCSc1cccc(Nc2nc(Cl)ncc2Cl)c1>>CC(C)(C)OC(=O)Nc1cccc(NCCSc2cccc(Nc3nc(Cl)ncc3Cl)c2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030055261A1,CN(C(=O)OC(C)(C)C)[C@@H](CNS(C)(=O)=O)Cc1ccccc1>>CN[C@@H](CNS(C)(=O)=O)Cc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060035895A1,Fc1ccc(C2=NOC(Cn3ccnn3)C2)cc1F.c1c[nH]cn1>>Fc1cc(C2=NOC(Cn3ccnn3)C2)ccc1-n1ccnc1,,CN(C)C=O,,[H-].[Na+],,test
US20020173527A1,Cc1nn(Cc2ccccc2)c2cc(C(=O)O)ccc12.O=C(Cl)C(=O)Cl>>CC1(C(=O)Cl)NN(Cc2ccccc2)c2ccccc21,CN(C)C=O,ClCCl,,,,test
US20030199550A1,CN(C[C@@H]1CC[C@@H](C#CCOS(C)(=O)=O)CC1)C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>CNC[C@@H]1CC[C@@H](C#CCOS(C)(=O)=O)CC1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US05010108,COc1cc(N)c(Cl)cc1C(=O)O.NCCNC1CC1>>COc1cc(N)c(Cl)cc1C(=O)NCCNC1CC1,,C1CCOC1,,O,O=C(n1ccnc1)n1ccnc1,test
US20070099895A1,CON(C)C(=O)C1CC1.COc1ccc(Br)c(C(=O)O)c1>>COc1ccc(C(=O)C2CC2)c(C(=O)O)c1,,CC(C)OC(C)C,,[Li]CCCC,,test
US20030109579A1,C/C(C#Cc1cccc(C#C/C(C)=C/CO)c1)=C\CO.C1CCOC1.CCOC(=O)N=NC(=O)OCC.CCOC(=O)[C@H](Cc1ccc(O)cc1)OCC.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CCOC(=O)[C@H](Cc1ccc(OC/C=C(\C)C#Cc2cccc(C#C/C(C)=C/COc3ccc(C[C@H](OCC)C(=O)OCC)cc3)c2)cc1)OCC,,C1CCOC1,O,,,test
US20130129677A1,CI.Nc1c(C(=O)Nc2nnc(-c3ccccc3)s2)sc2nc3c(cc12)CCCCC3>>CNc1c(C(=O)Nc2nnc(-c3ccccc3)s2)sc2nc3c(cc12)CCCCC3,,CN1CCCC1=O,,ClCCl,,test
US03978097,CC(CCOC(C)C)CCC(O)c1ccc2c(c1)OCO2>>CC(CC=Cc1ccc2c(c1)OCO2)CCOC(C)C,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100144801A1,O=C(Oc1ccc([N+](=O)[O-])cc1)N(Cc1ccccc1)c1ccccc1.OCc1ccccn1>>O=C(OCc1ccccn1)N(Cc1ccccc1)c1ccccc1,,Cc1ccccc1,,[H-].[Na+],,test
US20050288273A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCc2c(N)n[nH]c2-3)C(=O)O1.CC1(C)OC[C@@H](C(=O)O)O1>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCc2c(NC(=O)[C@@H]4COC(C)(C)O4)n[nH]c2-3)C(=O)O1,,c1ccncc1,,CCN=C=NCCCN(C)C,Cl,test
US20060025459A1,CCI.COC(=O)c1cc([N+](=O)[O-])c2cn[nH]c2c1>>CCn1ncc2c([N+](=O)[O-])cc(C(=O)OC)cc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06461876B1,O=C(CC(c1ccccc1)C1CCCCC1=O)c1ccccc1>>O=C1C2CCCC1C(c1ccccc1)C=C2c1ccccc1,,O,,CC(=O)O,Cl,test
US20150224113A1,NCc1ccccc1.O=C(O)c1ccc(Cl)nc1>>NC(=O)c1ccc(Cl)nc1Cc1ccccc1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140200206A1,CC1(Oc2nc(Cl)nc3c2c(I)cn3COCC[Si](C)(C)C)CCC1.Cc1nc2ccc(B3OC(C)(C)C(C)(C)O3)cc2o1>>Cc1nc2ccc(-c3cn(COCC[Si](C)(C)C)c4nc(Cl)nc(OC5(C)CCC5)c34)cc2o1,,O,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20100311693A1,COCc1ccccc1-c1cccc2nc(Nc3ccc4c(c3)CCN(C(=O)OC(C)(C)C)CC4)nn12>>COCc1ccccc1-c1cccc2nc(Nc3ccc4c(c3)CCNCC4)nn12,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110077240A1,COCCN(Cc1cnc(-c2cc3nccc(Oc4ccc(NC(=O)NC(C)C)cc4F)c3s2)n1C)C(=O)OC(C)(C)C>>COCCNCc1cnc(-c2cc3nccc(Oc4ccc(NC(=O)NC(C)C)cc4F)c3s2)n1C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060014826A1,COCC1C(=O)CC(=O)CC1(C)C.O=C=Nc1cccc(C(F)(F)F)c1>>COCC1C(=O)C(C(=O)Nc2cccc(C(F)(F)F)c2)C(=O)CC1(C)C,,C1CCOC1,,[H-].[Na+],,test
US05369110,CCC1(CC)CCC(=O)OC1=O.CCCCNCc1ccc(-c2ccccc2C#N)cc1>>CCCCN(Cc1ccc(-c2ccccc2C#N)cc1)C(=O)CCC(CC)(CC)C(=O)O,,C1COCCO1,,,,test
US20090005410A1,CCOC(=O)c1cn(-c2cc(Cl)ccc2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nn1>>CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-n2cc(C(=O)O)nn2)cc1,,C1CCOC1,,[Na+].[OH-],,test
US20090221555A1,O=C1NCCOc2cc([N+](=O)[O-])ccc21>>Nc1ccc2c(c1)OCCNC2=O,[Pd],CCO,,CN(C)C=O,,test
US20110017986A1,C=CCc1ccc(C)s1.Cl[SiH](Cl)Cl>>Cc1ccc(CCC[Si](Cl)(Cl)Cl)s1,[Pt],Cc1ccccc1,,,,test
US20070179173A1,COC(Cl)Cl.COc1cccc2c1CCC(=O)N2>>COc1ccc(C=O)c2c1CCC(=O)N2,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20100331549A1,Cc1ccncc1.O=Cc1ccc(C=O)cc1>>O=Cc1ccc(/C=C/c2ccncc2)cc1,,CC(=O)O,CC(=O)OC(C)=O,O,,test
US20140309227A1,C1CSC(C2CC2)CN1.Cn1cc(-c2cc(C#N)nc3cc(CBr)ccc23)cn1>>Cn1cc(-c2cc(C#N)nc3cc(CN4CCSC(C5CC5)C4)ccc23)cn1,,CC#N,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20080032986A1,COc1c(F)ccc(C(Nc2cccc3nc(C)ccc23)C(O)(CSc2nccn2C)C(F)(F)F)c1F>>Cc1ccc2c(NC(c3ccc(F)c(O)c3F)C(O)(CSc3nccn3C)C(F)(F)F)cccc2n1,,ClCCl,,BrB(Br)Br,,test
US04929618,Clc1ccc(C(OC2CCNCC2)c2ccccn2)cc1.OCCBr>>OCCN1CCC(OC(c2ccc(Cl)cc2)c2ccccn2)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050282812A1,CC(C)(C)OC(=O)C[C@@H]1CC[C@@H](C=O)CC1.CCC1CN(C(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(C)n2)c2cc(C(F)(F)F)ccc2N1>>CCC1CN(C(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(C)n2)c2cc(C(F)(F)F)ccc2N1C[C@@H]1CC[C@@H](CC(=O)OC(C)(C)C)CC1,CC(=O)O,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090012116A1,Nc1ccc(F)cc1.O=Cc1ccc(F)cc1>>Fc1ccc(NCc2ccccc2)cc1,,CC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05243042,O=C(Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)s1)OCc1ccccc1>>Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)s1,[Pd],CN(C)C=O,,,,test
US20080194660A1,CC(Cl)OC(=O)OCCCC[C@H](CO[N+](=O)[O-])O[N+](=O)[O-].CCCCc1nc(Cl)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCCc1nc(Cl)c(C(=O)OC(C)OC(=O)OCCCC[C@H](CO[N+](=O)[O-])O[N+](=O)[O-])n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20080113978A1,C1COCCN1.CCC(CC)c1c(Br)c(C)nn2c(-c3sc(Br)nc3C)c(C)nc12>>CCC(CC)c1c(Br)c(C)nn2c(-c3sc(N4CCOCC4)nc3C)c(C)nc12,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150152108A1,NC(CO)C(F)(F)F.O=C(O)c1ccc2c(n1)N(C(=O)Nc1ccccn1)[C@H]1CCN2C1>>O=C(NC(CO)C(F)(F)F)c1ccc2c(n1)N(C(=O)Nc1ccccn1)[C@H]1CCN2C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080076924A1,COc1c(OC)c(=O)c1=O.Cc1ccccc1N.O=C(Nc1ccc(Cl)cc1)N1CCNCC1c1ccccc1>>Cc1ccccc1Nc1c(N2CCN(C(=O)Nc3ccc(Cl)cc3)C(c3ccccc3)C2)c(=O)c1=O,,CO,,CCN(CC)CC,,test
US20100210617A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.Clc1cccc([Mg]Br)c1>>CC(C)(C)OC(=O)N1CCC(O)(c2cccc(Cl)c2)CC1,,[Cl-],[NH4+],C1CCOC1,,test
US20040176385A1,O=Cc1cccc(-c2cc(Nc3cccnc3)nc(N3CCOCC3)c2)c1>>OCc1cccc(-c2cc(Nc3cccnc3)nc(N3CCOCC3)c2)c1,,C1CCOC1,,CC(C)C[AlH]CC(C)C,,test
US20060160794A1,CN1CCNCC1.O=C(c1nnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1Cl)N1CCCC1c1ccccc1Cl>>CN1CCN(c2c(C(=O)N3CCCC3c3ccccc3Cl)nnn2Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1,,CCOC(C)=O,,,,test
US20050090499A1,C1COCCN1.O=C(O)c1ccc(Nc2nc(Br)cn3ccnc23)cc1>>O=C(c1ccc(Nc2nc(Br)cn3ccnc23)cc1)N1CCOCC1,,O,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US20090098218A1,CCOC(=O)C1(C#N)CN(C(=O)OC(C)(C)C)C1>>COC(=O)C1(CN)CN(C(=O)OC(C)(C)C)C1,[Ni],CO,,[H][H],,test
US20090286811A1,COc1cccc(C=O)c1OCCC(C)C.Cc1nc2sccn2c(=O)c1-c1ccc(OC(F)(F)F)cc1>>COc1cccc(/C=C/c2nc3sccn3c(=O)c2-c2ccc(OC(F)(F)F)cc2)c1OCCC(C)C,,CCO,,C,C[O-].[Na+],test
US20070299092A1,COCCOc1cc2ncnc(NC3=CC(=O)C(Cl)=CC3=O)c2cc1OC.Cc1ccccc1O>>COCCOc1cc2ncnc(NC3=CC(=O)C(Oc4ccccc4C)=CC3=O)c2cc1OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05686457,Cc1c(C)n(Cc2ccccc2)c2ncnc(Nc3cccc(Cl)c3)c12>>Cc1[nH]c2ncnc(Nc3cccc(Cl)c3)c2c1C,,Cc1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20090247507A1,CC(C)CN1CCN(c2c(Cl)cnc(N)c2[N+](=O)[O-])CC1.COc1ccc(C=O)cc1>>COc1ccc(-c2nc3c(N4CCN(CC(C)C)CC4)c(Cl)cnc3[nH]2)cc1,,CCO,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20090192156A1,OC1CCC1.Oc1ccncc1>>c1cc(OC2CCC2)ccn1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090105257A1,Cc1nc(Oc2ccc(F)c(F)c2)sc1C=O.Nc1ccc([C@@H]2C[C@H]2C(=O)O)cc1>>Cc1nc(Oc2ccc(F)c(F)c2)sc1CNc1ccc([C@@H]2C[C@H]2C(=O)O)cc1,,CC(Cl)Cl,,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20150210632A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](CO)Cc1ccc(-c2ccccc2)cc1>>CC(C)(C)OC(=O)N[C@@H](CO)Cc1ccc(-c2ccccc2)cc1,,CCO,O,Cl,[Na+].[OH-],test
US20080234306A1,O=C(OO)c1cccc(Cl)c1.O=C1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5>>C[N+]1([O-])CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@H]3[C@H]1C5,,ClCCl,,Cl,,test
US20140051713A1,CN(C)C/C=C/C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1.O=C(O)CC(O)(CC(=O)O)C(=O)O>>CN(C)C/C=C/C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1.O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-],,CCO,,,,test
US20140275015A1,Cc1cc(Cl)c([N+](=O)[O-])c(Cl)n1.Nc1ncc(F)cn1>>Cc1cc(Nc2ncc(F)cn2)c([N+](=O)[O-])c(Cl)n1,,C1CCOC1,CCOC(C)=O,CCO,[H-].[Na+],test
US20020094963A1,CC(C)N.O[C@@H]1CC[C@@H](n2c(Br)nc3cc(Cl)c(Cl)cc32)C[C@@H]1O>>CC(C)Nc1nc2cc(Cl)c(Cl)cc2n1[C@@H]1CC[C@@H](O)[C@@H](O)C1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20040220191A1,CCOC(=O)C1CCN(c2ccc(F)cc2)CC1>>O=C(O)C1CCN(c2ccc(F)cc2)CC1,,CO,,Cl,[K+].[OH-],test
US20150329538A1,Nc1c(Br)cccc1C(=O)NC1CCOCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=c1[nH]c2c(Br)cccc2c(=O)n1C1CCOCC1,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20150197530A1,Cc1cc(C(=O)c2ccco2)sc1-c1ccc(F)cc1.O=C1CCC(=O)N1Br>>O=C(c1ccco1)c1cc(CBr)c(-c2ccc(F)cc2)s1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US03948854,CCOC(=O)Cl.NNC(=O)c1cc(Cl)ccc1O>>CCOC(=O)N(N)C(=O)c1cc(Cl)ccc1O,,CC(=O)N(C)C,,c1ccncc1,,test
US20050234109A1,Cc1ccnc(Br)c1.O=Cc1cc(F)ccc1F>>Cc1ccnc(C(O)c2cc(F)ccc2F)c1,,C1CCOC1,,CC(C)[Mg]Cl,[Cl-].[NH4+],test
US20070244140A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.NS(=O)(=O)c1ccc(Nc2nccc(-c3ccc(O)cc3)n2)cc1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)Oc1ccc(-c2ccnc(Nc3ccc(S(N)(=O)=O)cc3)n2)cc1,,ClCCl,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20090054644A1,C[C@@H]1CNCCN1S(C)(=O)=O.ClCCl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>C[C@@H]1CN(C(=O)Cl)CCN1S(C)(=O)=O,,ClCCl,,c1ccncc1,,test
US20080171755A1,COC(OC)N(C)C.Cc1nccc(C(=O)Cc2ccc3nccnc3c2)n1.NN>>Cc1nccc(-c2n[nH]cc2-c2ccc3nccnc3c2)n1,,CN(C)C=O,,CC(=O)O,O,test
US20100249119A1,CC(=O)OC(C)=O.N#CC1(c2cccc(C(=O)Nc3cc(Oc4ccc5nc(NC(=O)C6CC6)sc5n4)ccc3F)c2Cl)CC1>>CC(=O)N(C(=O)c1cccc(C2(C#N)CC2)c1Cl)c1cc(Oc2ccc3nc(NC(=O)C4CC4)sc3n2)ccc1F,CN(C)c1ccncc1,c1ccncc1,,O,,test
US06143907,CCCOc1ccc2c(c1)C(=O)C=C2c1ccc2c(c1)OCO2>>CCCOc1ccc2c(c1)C(=O)C[C@H]2c1ccc2c(c1)OCO2,,CO,,C1CCOC1,CCN(CC)CC,test
US20070032525A1,COc1ccc2c(C[N+](C)(C)C)cn(C)c2c1.c1ccc2[nH]c(NCC3CCNCC3)nc2c1>>COc1ccc2c(CN3CCC(CNc4nc5ccccc5[nH]4)CC3)cn(C)c2c1,,CC#N,,[I-].[K+],,test
US20050239832A1,O=c1ccoc2ccccc12>>OC1=CCOc2ccccc21,,CO,,[BH4-].[Na+],,test
US20050203153A1,CC(C)O.O=[N+]([O-])c1ccc(F)c(-c2nc3cc(-c4ccccc4)ccc3o2)c1>>CC(C)Oc1ccc([N+](=O)[O-])cc1-c1nc2cc(-c3ccccc3)ccc2o1,,CC(C)O,,,,test
US05281593,ClCc1ccccc1.O=[N+]([O-])c1cc(Cl)ccc1O>>O=[N+]([O-])c1cc(Cl)ccc1OCc1ccccc1,,CN(C)C=O,O,[H-].[Na+],,test
US20120115882A1,C1CCC2(C1)CCNCC2.CC(C)(C)OC(=O)OC(=O)[O-]>>CC(C)(C)OC(=O)N1CCC2(CCCC2)CC1,,ClCCl,,CCN(CC)CC,,test
US04478758,BrCCBr.CCOC(=O)CN=Cc1ccccc1>>CCOC(=O)C1(N=Cc2ccccc2)CC1,,CCOCC,CS(C)=O,[H-].[Na+],,test
US20040110754A1,CON(C)C(=O)C1CC1c1ccc(Cl)cc1.[OH-]>>O=C(O)C1CC1c1ccc(Cl)cc1,,CO,,O,,test
US04147794,CC(=O)NNc1nnc(-c2ccccc2C)s1.CI>>CC(=O)N(C)Nc1nnc(-c2ccccc2C)s1,,CCO,,[Na],,test
US03997535,CCOC(=O)c1nc2cc(OC)c(OC)cc2nc1Cl.C[O-]>>COc1cc2nc(OC)c(C(=O)O)nc2cc1OC,,O,,Cl,,test
US20140349998A1,C=C(C)C(=O)Cl.CCOC(=O)c1c[nH]c2ncnc(-c3cccc(N)c3F)c12>>C=C(C)C(=O)Nc1cccc(-c2ncnc3[nH]cc(C(=O)OCC)c23)c1F,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20130059846A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(C#N)cc1N>>Cc1ccc(C#N)cc1NC(=O)OC(C)(C)C,CN(C)c1ccncc1,C1CCOC1,,,,test
US20040092502A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1[C@@H]2CNC[C@H]2c2cccc3c2N1CCC3>>CC(C)(C)OC(=O)N1C[C@H]2c3cccc4c3N(CCC4)C(=O)[C@@H]2C1,,ClCCl,,CCN(CC)CC,Cl,test
US20130274242A1,CCn1cc(C=O)c(C)n1.Clc1ccnc(Cl)n1>>Cc1nn(-c2ccnc(Cl)n2)cc1C=O,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20150353553A1,COC(=O)c1nc(N[C@H](C)C2CCC2)c2c(n1)nc(-c1cccc(OC)c1)n2Cc1ccc(C(F)(F)F)cc1>>COc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1,,C1CCOC1,,[Li+].[OH-],,test
US20050282823A1,CCOC(=O)N(CO)CC1CC=CCC1>>CCOC(=O)N1CC2C=CCC(C2)C1,,ClCCl,,CCOCC,FB(F)F,test
US20140194431A1,CC(C)(C)[Si](C)(C)OCCNC(=O)c1nc(CC2(c3cccc4ccccc34)CCCC2)nc(O)c1OCc1ccccc1>>O=C(NCCO)c1nc(CC2(c3cccc4ccccc34)CCCC2)nc(O)c1OCc1ccccc1,,C1CCOC1,,CO,Cl,test
US20080242692A1,COc1ccc(OC)c(C=NCC(OC)OC)c1>>COc1ccc(OC)c(CNCC(OC)OC)c1,,CCO,,[BH4-].[Na+],,test
US20120238541A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccccc4)oc4c(ccc5[nH]ncc54)c3=O)cc2)CCC1.CI>>Cn1cc2c(ccc3c(=O)c(-c4ccc(C5(NC(=O)OC(C)(C)C)CCC5)cc4)c(-c4ccccc4)oc32)n1,,CN(C)C=O,,[H-].[Na+],,test
US20160083343A1,O=C(c1cccnc1)N1CCC[C@H]1CO.O=Cc1c(O)cccc1O>>O=Cc1c(O)cccc1OC[C@@H]1CCCN1C(=O)c1ccncc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080300276A1,CCOP(=O)(Cc1ccccc1)OCC.O=C1CCN(Cc2ccccc2)CC1>>C(=C1CCN(Cc2ccccc2)CC1)c1ccccc1,,CCO,O,CN(C)C=O,[H-].[Na+],test
US20090275537A1,CN(C(=O)NCc1cccc(F)c1Cl)[C@H](CO)CCCN1C(=O)c2ccccc2C1=O.O=C(O)c1ccc(Cl)cn1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CN(C(=O)NCc1cccc(F)c1Cl)[C@@H](CCCN1C(=O)c2ccccc2C1=O)COC(=O)Nc1ccc(Cl)cn1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20030119827A1,CCCN1CCC(C#N)(NC(=O)C(O)CC(C)C)CC1.NCc1ccccc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCCN1CCC(C#N)(NC(=O)C(CC(C)C)OC(=O)NCc2ccccc2)CC1,CN(C)c1ccncc1,ClCCl,,CN1CCOCC1,,test
US20080306046A1,C(CC1CCNCC1)CC1CCNCC1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCC(CCCC2CCNCC2)CC1,,ClC(Cl)Cl,,ClCCl,,test
US20120208817A1,CCOc1cc(C=O)cc([N+](=O)[O-])c1O.NC(N)=O.O=C(Cc1ccccc1)c1ccn(S(=O)(=O)c2ccccc2)c1>>CCOc1cc(C2NC(=O)NC(c3ccn(S(=O)(=O)c4ccccc4)c3)=C2c2ccccc2)cc([N+](=O)[O-])c1O,,CCO,,Cl,,test
US20050261376A1,COc1cc2c(cc1OC)C(C#N)C2>>COc1cc2c(cc1OC)C(CN)C2,[Ni],CO,,N,,test
US06130239,C#CCCC(N)=O.COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(I)c21>>COc1cc[nH]c1/C=C1\C(=O)Nc2cccc(C#CCCC(N)=O)c21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCN(CC)CC,CN(C)C=O,,,test
US20090048300A1,CN(C)CCN.COC(=O)C=Cc1ccc(Cl)c([N+](=O)[O-])c1>>COC(=O)C=Cc1ccc(NCCN(C)C)c([N+](=O)[O-])c1,,C1COCCO1,,CCN(CC)CC,,test
US20080242685A1,CCOP(OCC)OCC.O=[N+]([O-])c1cncnc1CBr>>CCOP(=O)(Cc1ncncc1[N+](=O)[O-])OCC,,Cc1ccccc1,,,,test
US20080161328A1,CCCCCCC(=O)Cl.Cc1nc2cccc(N)c2c(=O)n1C1CCC(=O)NC1=O>>CCCCCCC(=O)Nc1cccc2nc(C)n(C3CCC(=O)NC3=O)c(=O)c12,,C1CCOC1,,,,test
US04405333,O=[N+]([O-])O.OC1CCCOC1>>O=[N+]([O-])OC1CCCOC1,,CC(=O)OC(C)=O,,,,test
US20040116690A1,CN(C)C(=O)Cl.COc1cc[n+]([O-])cc1.COc1ccnc(C(=O)O)c1.C[Si](C)(C)C#N.ClCCl>>CCCCCc1ccnc(C#N)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20090186870A1,COC(=O)c1cc(NN)c(OC(C)C)cc1Cl.COC(CC(OC)OC)OC>>COC(=O)c1cc(-n2cccn2)c(OC(C)C)cc1Cl,,CCO,,,,test
US20090036422A1,COc1ccc(N(CCc2ccc(C(F)(F)F)cc2)C(=O)[C@@H](NC(=O)OC(C)(C)C)c2ccccc2)cc1OC.Cl>>COc1ccc(N(CCc2ccc(C(F)(F)F)cc2)C(=O)[C@@H](N)c2ccccc2)cc1OC.Cl,,C1COCCO1,,,,test
US20140315911A1,CCOC(=O)C(C)OS(=O)(=O)C(F)(F)F.Nc1ccccc1>>CCOC(=O)[C@H](C)Nc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US05104867,CCNC(=O)[C@@H]1C[C@H](SCc2ccc(OC)cc2)CN1C(=O)OC(C)(C)C>>CCNC(=O)[C@@H]1C[C@H](SCc2ccc(OC)cc2)CN1,,CCOC(C)=O,,Cl,O=C([O-])O.[Na+],test
US20070173505A1,Cc1noc(C)c1CCl.Nc1nc(N2CC3CC2CN3)cc2nc(-c3ccco3)nn12>>Cc1noc(C)c1CN1CC2CC1CN2c1cc2nc(-c3ccco3)nn2c(N)n1,,CC#N,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20110294807A1,Nc1ccc(F)cc1.O=c1[nH]c2ccccc2c(=O)o1>>Nc1ccccc1C(=O)Nc1ccc(F)cc1,,CCOC(C)=O,CN(C)C=O,,,test
US20040110807A1,CCCCOCC(=O)OC.Cc1cc(OCc2ccccc2)ccc1C=O>>CCCCOC(C(=O)OC)C(O)c1ccc(OCc2ccccc2)cc1C,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20110275801A1,CS(=O)(=O)Cl.Cc1nc([C@@H]2CC[C@@H](c3nnc4n3-c3ccc(Cl)cc3CNC4)CC2)no1>>Cc1nc([C@@H]2CC[C@@H](c3nnc4n3-c3ccc(Cl)cc3CN(S(C)(=O)=O)C4)CC2)no1,,ClCCl,,CCN(CC)CC,Cl,test
US04935413,C=C(C)C(=O)N=C=O.N>>C=C(C)C(=O)NC(N)=O,,ClCCCl,,ClC(Cl)Cl,,test
US05420164,CN(C(=O)Cl)C1CCCCC1c1ccccc1.Cc1cccc(C(C)(C)C)c1N>>Cc1cccc(C(C)(C)C)c1NC(=O)N(C)C1CCCCC1c1ccccc1,,ClCCl,c1ccncc1,,,test
US20150126523A1,NCCCCl.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NCCCCl)C(F)(F)F,,c1ccncc1,,Cl,ClCCl,test
US20120329775A1,CC(C)(C)OC(=O)NC1(C(=O)N[C@@H](Cc2ccc(-c3cccc(OS(C)(=O)=O)c3)cc2)C(N)=O)CCOCC1>>CS(=O)(=O)Oc1cccc(-c2ccc(C[C@@H](C#N)NC(=O)C3(N)CCOCC3)cc2)c1,,ClCCl,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US20120226053A1,COC(=O)c1ccc(O)cc1.Fc1ccccc1CBr>>COC(=O)c1ccc(OCc2ccccc2F)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090156590A1,CCOC(=O)C(C)c1ccc([N+](=O)[O-])c(O)c1>>CCOC(=O)C(C)c1ccc(N)c(O)c1,[Pd],C1CCOC1,CCO,,,test
US20140221344A1,Cc1ccc(-c2ncccc2Cl)nn1.O=c1n(Cl)c(=O)n(Cl)c(=O)n1Cl>>ClCc1ccc(-c2ncccc2Cl)nn1,,ClCCCl,,,,test
US20060135578A1,CCOC(=O)Cc1ccc(OCc2nc(-c3ccco3)oc2C)c(OC)c1>>COc1cc(CC(=O)O)ccc1OCc1nc(-c2ccco2)oc1C,,[K+],[OH-],Cl,,test
US20080293951A1,CCCN(CCC)CCCCNCc1ccc(C#N)cc1.O=Cc1ccc(Br)cc1>>CCCN(CCC)CCCCN(Cc1ccc(Br)cc1)Cc1ccc(C#N)cc1,,CCO,,O=C([O-])O.[Na+],,test
US20080171403A1,CC1(C)OC2C=CC=CC2O1.O=S(=O)(/C=C/S(=O)(=O)c1ccccc1)c1ccccc1>>CC1(C)OC2C3C=CC(C2O1)C(S(=O)(=O)c1ccccc1)C3S(=O)(=O)c1ccccc1,,Cc1ccccc1,,,,test
US05952354,O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.O=C(NCCCCCCO)OC1CCN(C(=O)Oc2ccc(Oc3ccccc3)cc2)CC1>>O=C(NCCCCCCOC(=O)Oc1ccc([N+](=O)[O-])cc1)OC1CCN(C(=O)Oc2ccc(Oc3ccccc3)cc2)CC1,,ClCCl,,c1ccncc1,,test
US04577015,NCCO.O=[N+]([O-])c1ccc(Cl)c(S(=O)[O-])c1.[Na+]>>O=[N+]([O-])c1ccc(NCCO)c(S(=O)[O-])c1.[Na+],,O,,Cl,,test
US20090130076A1,CO.Nc1nc2c(Br)cc(C(=O)O)cc2s1>>COC(=O)c1cc(Br)c2nc(N)sc2c1,,C1CCOC1,CO,C[Si](C)(C)C=[N+]=[N-],,test
US20080318878A1,O=C1c2ccccc2C(=O)N1CCCBr.Oc1cccc(Br)c1>>O=C1c2ccccc2C(=O)N1CCCOc1cccc(Br)c1,,CN(C)C=O,,[H-].[Na+],,test
US20120264734A1,Cc1cc(C)c(CNC(=O)c2cc(Br)cc(NC3CCCC3)c2C)c(=O)[nH]1.O=Cc1ccc(B(O)O)cc1>>Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(C=O)cc3)cc(NC3CCCC3)c2C)c(=O)[nH]1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20050261277A1,CCOC(C)OCc1cc(OC)ccc1Br.COB(OC)OC>>COc1ccc2c(c1)COB2O,,C1CCOC1,,Cl,[Li]CCCC,test
US20110312963A1,COCC(=O)Nc1cc(Oc2ccc([N+](=O)[O-])cc2C)ccn1>>COCC(=O)Nc1cc(Oc2ccc(N)cc2C)ccn1,[Pt],CC(=O)O,CO,[H][H],,test
US20090136513A1,CCOC(=O)n1nc(NC(=O)c2ccc(N3CCN(C)CC3)c([N+](=O)[O-])c2)c2c1CN(S(=O)(=O)c1cccc(F)c1)C2>>CCOC(=O)n1nc(NC(=O)c2ccc(N3CCN(C)CC3)c(N)c2)c2c1CN(S(=O)(=O)c1cccc(F)c1)C2,,CCO,Cl,Cl[Sn]Cl,,test
US20080242655A1,CC1(C)OCC(CONC(=O)c2c(Nc3ccc(I)cc3F)c3cnccc3n2C2CC2)O1>>O=C(NOCC(O)CO)c1c(Nc2ccc(I)cc2F)c2cnccc2n1C1CC1,,C1COCCO1,CO,Cl,,test
US05364866,CSc1cc(C(C)=O)ccc1OCCCBr.Fc1ccc2c(C3CCNCC3)noc2c1>>CSc1cc(C(C)=O)ccc1OCCCN1CCC(c2noc3cc(F)ccc23)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130085148A1,C[Mg]Br.O=Cc1cnc(-c2ccc(F)cc2)s1>>CC(O)c1cnc(-c2ccc(F)cc2)s1,,C1CCOC1,,CCOCC,,test
US20120196833A1,Fc1cccc(CBr)c1.O=[N+]([O-])c1cc2cn[nH]c2c2ccccc12>>O=[N+]([O-])c1ccc2c(cnn2Cc2cccc(F)c2)c1,,CC(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20040067999A1,Cc1c([N+](=O)[O-])ccc2c1c1ccccc1n2S(C)(=O)=O>>Cc1c(N)ccc2c1c1ccccc1n2S(C)(=O)=O,[Pd],CCOC(C)=O,,[H][H],,test
US03965099,CC(Sc1nnn[nH]1)C1=C(C(=O)O)N2C(=O)C(NC(=O)CSC(F)(F)F)[C@H]2SC1.COC(=O)OCCl>>COC(=O)OCOC(=O)C1=C(C(C)Sc2nnn[nH]2)CS[C@@H]2C(NC(=O)CSC(F)(F)F)C(=O)N12,,CN(C)C=O,,[Na],,test
US20070275968A1,Cc1cccc(-c2nn(COCC[Si](C)(C)C)cc2-c2ccc(F)c(B3OC(C)(C)C(C)(C)O3)c2)n1.NS(=O)(=O)c1ccc(Br)cc1F>>Cc1cccc(-c2n[nH]cc2-c2ccc(F)c(-c3ccc(S(N)(=O)=O)c(F)c3)c2)n1,,CCOC(C)=O,COCCOC,O,,test
US05594145,Nc1nc2ccc([N+](=O)[O-])cc2s1.O=N[O-]>>O=c1[nH]c2ccc([N+](=O)[O-])cc2s1,,O,,Cl,,test
US20100173880A1,CN(c1ccc(F)cc1)C(C(=O)O[C@H]1CN2CCC1CC2)c1ccccc1.O=C(CCl)c1cccs1>>CN(c1ccc(F)cc1)C(C(=O)O[C@H]1C[N+]2(CC(=O)c3cccs3)CCC1CC2)c1ccccc1.[Cl-],,CCOC(C)=O,,,,test
US20090227622A1,C1COCCN1.CC(=O)Cc1cc(-c2ccn3ccnc3c2)ccn1>>CC(Cc1cc(-c2ccn3ccnc3c2)ccn1)N1CCOCC1,,CO,,Cl,[BH3-]C#N.[Na+],test
US20080306053A1,Cc1sc(N)c(C#N)c1C.O=C(N=C=S)c1ccccc1>>Cc1sc(NC(=S)NC(=O)c2ccccc2)c(C#N)c1C,,C1COCCO1,,,,test
US04283532,O=C(O)Cc1ccccc1Br.O=S(Cl)Cl>>O=C(Cl)Cc1ccccc1Br,,c1ccccc1,,,,test
US05856503,C=CCN(C)CCCCCCOc1ccc(C(=O)c2ccc(Br)cc2)c(F)c1.CO>>C=CCN(C)CCCCCCOc1ccc(C(=O)c2ccc(Br)cc2)c(OC)c1,,C1CCOC1,CO,C[O-].[Na+],,test
US20060173018A1,Cc1ccc2c(N3CCN(C(=O)[C@H](O)CC(C)C)CC3)nc(-c3ccccc3O)nc2c1.Cl>>Cc1ccc2c(N3CCN(C(=O)[C@H](O)CC(C)C)CC3)nc(-c3ccccc3O)nc2c1.Cl,,ClCCl,,CCOCC,,test
US20160200639A1,Cc1ccnc2c1ccc1c(C)ccnc12.[Li]C>>Cc1cc(C)c2ccc3c(C)ccnc3c2n1,O=[Mn]=O,C1CCOC1,,,,test
US06011028,Cl.Cl.N=C1CCCCC(CCc2ccccn2)N1>>Cl.Cl.N=C1CCCCC(CCC2CCCCN2)N1,O=[Pt],Cl,,CCO,[H][H],test
US04228288,CCCC1(c2cccc(OC)c2)CCN(C)CC1C>>CCCC1(c2cccc(OC)c2)C=CN(C)CC1C,,CC(=O)O,,,,test
US05155268,CS(=O)(=O)Nc1ccccc1.O=C1CCC(=O)O1>>CS(=O)(=O)Nc1ccc(C(=O)CCC(=O)O)cc1,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20050153942A1,CC(C)=NO.COC(=O)c1nc(C(C)=O)c(Cl)c(F)c1Nc1ccccc1F>>COC(=O)c1nc(C(C)=O)c(ON=C(C)C)c(F)c1Nc1ccccc1F,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US06479512B1,CC(C)(C)OC(=O)Nc1sccc1C=O.CCOC(=O)CC(=O)OCC>>CCOC(=O)c1cc2ccsc2[nH]c1=O,,CCO,,C1CCNCC1,,test
US20120202785A1,C[C@H](N)c1nc2ccc(C#N)cc2n1-c1ccccc1.Clc1ncnc2[nH]cnc12>>C[C@H](Nc1ncnc2[nH]cnc12)c1nc2ccc(C#N)cc2n1-c1ccccc1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20040157886A1,N#Cc1cccc(N)c1.O=C(CCl)N1CCC(Cc2ccc(F)cc2)CC1>>N#Cc1cccc(NCC(=O)N2CCC(Cc3ccc(F)cc3)CC2)c1,,CCOCC,,,,test
US20110319277A1,NC1(CCCCNC(=O)OCc2ccccc2)CCC(=O)NC1=O.O=C1OC(=O)c2cc([N+](=O)[O-])ccc21>>O=C1CCC(CCCCNC(=O)OCc2ccccc2)(N2C(=O)c3ccc([N+](=O)[O-])cc3C2=O)C(=O)N1,,CC(=O)O,,Cl,CC(=O)[O-].[Na+],test
US20130225552A1,COC(=O)/C=C/c1ncccc1N>>O=c1ccc2ncccc2[nH]1,,CO,,C[O-].[Na+],,test
US04402960,COc1ccc(-c2nc(Sc3ccc(Cl)cc3)[nH]c2-c2ccc(OC)cc2)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(-c2nc(S(=O)c3ccc(Cl)cc3)[nH]c2-c2ccc(OC)cc2)cc1,,ClCCl,,,,test
US20090291956A1,CCOC(C#Cc1ccc2ncccc2c1)OCC>>CCOC(CCc1ccc2ncccc2c1)OCC,[Pd],C1CCOC1,,,,test
US20070185103A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C1CNc2ccccc2O1>>CCOC(=O)C1CN(C(=O)OC(C)(C)C)c2ccccc2O1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20020052495A1,CO.CS(=O)(=O)c1nc(Cl)c2c(n1)CCC2>>COc1nc(S(C)(=O)=O)nc2c1CCC2,,CO,,C[O-].[Na+],,test
US20120157436A1,CCOC(=O)c1nc(C)cs1.NN>>Cc1csc(C(=O)NN)n1,,CCO,,,,test
US20130274241A1,C#Cc1n[nH]c2ccc(C(=O)OC)cc12.C1=COCCC1>>C#Cc1nn(C2CCCCO2)c2ccc(C(=O)OC)cc12,,COCCOC,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20050070592A1,CI.Cc1[nH]c2ccc(Br)cc2c1Cc1ccccc1>>Cc1c(Cc2ccccc2)c2cc(Br)ccc2n1C,,CN(C)C=O,,,,test
US20150210657A1,c1ccc(-c2cnc3ccccc3n2)cc1>>c1ccc([C@@H]2CNc3ccccc3N2)cc1,,Cc1ccccc1,,,,test
US20050124656A1,CCCCCCCCCCCC#N.NO>>CCCCCCCCCCCC(=N)NO,,CCO,,,,test
US20150376165A1,CI.FC(F)(F)c1ccnc(N=C=S)c1.N#CN>>CSC(NC#N)Nc1cc(C(F)(F)F)ccn1,,CO,,C[O-].[Na+],,test
US20110021537A1,CCOC(=O)N1CCN(C(=O)[C@@H](N)CC2COC(C)(C)O2)CC1.O=C(O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1>>CCOC(=O)N1CCN(C(=O)[C@H](CC2COC(C)(C)O2)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)NC3CCC3)n(-c3ccccc3)n2)CC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110021522A1,Nc1cccc(-c2cn3ccccc3n2)c1.O=C(O)c1cc2cccc(OC(F)(F)F)c2oc1=O>>O=C(Nc1cccc(-c2cn3ccccc3n2)c1)c1cc2cccc(OC(F)(F)F)c2oc1=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130158006A1,COS(=O)(=O)OC.Cc1c(C(=O)O)ccc([N+](=O)[O-])c1O>>COC(=O)c1ccc([N+](=O)[O-])c(OC)c1C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05317016,COC(=O)[C@@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C.O=CO>>COC(=O)[C@@H]1C[C@H](OC=O)CN1C(=O)OC(C)(C)C,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090176770A1,CC(C)(C)ON1CCC(N2CCN(C(=O)[C@@H](Cc3ccc(O)cc3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1=C=O>>O=C(O[C@H](Cc1ccc(O)cc1)C(=O)N1CCN(C2CCNCC2)CC1)N1CCC(N2CCc3ccccc3NC2=O)CC1,,O=CO,,,,test
US07601738B2,CCOC(=O)[C@@H]1C[C@@H]2C[C@@H](Oc3cc(-n4cccn4)ccc3-c3nn[nH]n3)CC[C@H]2CN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1C[C@@H]2CC[C@H](Oc3cc(-n4cccn4)ccc3-c3nn[nH]n3)C[C@@H]2C[C@H]1C(=O)O,,CO,,[Na+].[OH-],,test
US20050065155A1,CC(C)(C)OC(=O)N1CCCC(CO)C1.Cc1ccc(S(=O)(=O)O)cc1>>Cc1ccc(S(=O)(=O)OCC2CCCN(C(=O)OC(C)(C)C)C2)cc1,,c1ccncc1,,,,test
US20110311461A1,CCOC(=O)c1cccc(NC(C(=O)O)c2ccc(OC)nc2)c1.O[C@H]1CN2CCC1CC2>>CCOC(=O)c1cccc(NC(C(=O)O[C@H]2CN3CCC2CC3)c2ccc(OC)nc2)c1,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20060111347A1,N[C@@H]1CCCc2cc(CN3CCCCC3)ccc21.O=C(O)CCCS(=O)(=O)c1ccc2ccccc2c1>>O=C(CCCS(=O)(=O)c1ccc2ccccc2c1)N[C@@H]1CCCc2cc(CN3CCCCC3)ccc21,,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20050014942A1,C1CNCCN1.COC(=O)c1cnc(Cl)cn1>>COC(=O)c1cnc(N2CCNCC2)cn1,,Cc1ccccc1,,,,test
US20090048281A1,CCOC(=O)C(=O)c1cccs1.Cl[Mg]C1CCCCC1>>CCOC(=O)C(O)(c1cccs1)C1CCCCC1,,CCOCC,CCOCC,,,test
US20120322801A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(N)c1ccc(C(=O)O)cc1Br>>CC(NC(=O)OC(C)(C)C)c1ccc(C(=O)O)cc1Br,,C1CCOC1,,CC(C)=O,,test
US20050287566A1,CC(C)C(=O)Nc1nc2c(ncn2[C@@H]2O[C@@]3(CO)CO[C@@H]2[C@@H]3O)c(=O)[nH]1.COc1ccc(C(Cl)(c2ccccc2)c2ccc(OC)cc2)cc1>>COc1ccc(C(OC[C@@]23CO[C@@H]([C@H](n4cnc5c(=O)[nH]c(NC(=O)C(C)C)nc54)O2)[C@@H]3O)(c2ccccc2)c2ccc(OC)cc2)cc1,,c1ccncc1,,,,test
US20120114739A1,CCOC(=O)CC1CCC(c2cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n3nccc3n2)CC1.O=C1CCC(=O)N1I>>CCOC(=O)CC1CCC(c2cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n3ncc(I)c3n2)CC1,,CC#N,,,,test
US20140142081A1,O=CC1CCC(C=O)C1>>OCC1CCC(CO)C1,,O,,[BH4-].[Na+],,test
US20150295179A1,CCCCCCCCCCCCC(CCCCCCCCCC)CCC(=O)O>>CCCCCCCCCCCCC(CCCO)CCCCCCCCCC,,CCOCC,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20160024103A1,CCC(C)c1cc2oc(-c3ccc(F)cc3)c(C(=O)NC)c2cc1OC(C)C>>CCC(C)c1cc2oc(-c3ccc(F)cc3)c(C(=O)NC)c2cc1O,,ClCCl,,ClB(Cl)Cl,,test
US05554607,CC(C)c1cccc(C(C)C)c1N=C=S.CCNCC(=O)O>>CCN1CC(=O)N(c2c(C(C)C)cccc2C(C)C)C1=S,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20090247517A1,O=C(Cl)N1CCOCC1.O=c1c2cn[nH]c2nc(-c2ccccc2F)n1-c1ccc(Br)cc1>>O=C(N1CCOCC1)n1ncc2c(=O)n(-c3ccc(Br)cc3)c(-c3ccccc3F)nc21,,c1ccncc1,,,,test
US20060135605A1,CCOC(=O)CCl.COC(OC)C(O)c1cc(C)c(O)cc1C>>CCOC(=O)COc1cc(C)c(C(O)C(OC)OC)cc1C,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US03931195,CCOC(=O)c1ccccn1.CN1CCCCC1CCc1ccccc1N>>CN1CCCCC1CCc1ccccc1NC(=O)c1ccccn1,,CS(C)=O,,O,[H-].[Na+],test
US20150175560A1,O=C(NO)c1cc(Br)ccc1O>>Oc1noc2ccc(Br)cc12,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20090197862A1,COC(=O)C(OC)OC.NCc1ccccc1Cl>>COC(OC)C(=O)NCc1ccccc1Cl,,CCOC(C)=O,,,,test
US20100168122A1,CCCCCn1c(=O)n(CCCCC(=O)OCC)c(=O)c2[nH]c(Cl)nc21.[H]/N=C(/Cc1c(Cl)cccc1Cl)NO>>CCCCCn1c(=O)n(CCCc2nc(Cc3c(Cl)cccc3Cl)no2)c(=O)c2[nH]c(Cl)nc21,,CCO,,C,C[O-].[Na+],test
US20100068197A1,COc1ccc(N(C)c2nc(NCCO)nc3ccccc23)cc1.O=C(N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)OCc1ccccc1>>COc1ccc(N(C)c2nc(NCCOC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)OCc3ccccc3)nc3ccccc23)cc1,,C1CCOC1,,CCN(CC)CC,O=C1OCCN1P(=O)(Cl)N1CCOC1=O,test
US20140171408A1,O=C(Cl)C(=O)Cl.O=C(O)/C=C/c1csc(-c2c(Cl)cccc2Cl)n1>>O=C(Cl)/C=C/c1csc(-c2c(Cl)cccc2Cl)n1,CN(C)C=O,ClCCl,,,,test
US20090069420A1,C1CCOC1.CCOC(=O)c1ccc(NC(=O)CC(CNS(=O)(=O)c2ccc(C)cc2)c2ccc(Cl)cc2)cc1>>O=C(CC(CNS(=O)(=O)c1ccc(Oc2ccccc2)cc1)c1ccc(Cl)cc1)Nc1ccc(C(=O)O)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20100120763A1,COc1cc(C(F)(F)F)cc2c1nnc1c(C)nc(Br)n12.Cc1noc(C)c1B(O)O>>COc1cc(C(F)(F)F)cc2c1nnc1c(C)nc(-c3c(C)noc3C)n12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150038437A1,CCc1c(-c2ccc3c(ccn3C)c2OCc2ccccc2)[nH]c(=O)c(C(=O)OC)c1O>>CCc1c(-c2ccc3c(ccn3C)c2O)[nH]c(=O)c(C(=O)OC)c1O,[Pd],CCOC(C)=O,ClCCl,,,test
US04587262,CCCCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CC(C)(C)CC(=O)Cl.Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl>>CCCCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CC(C)(C)CC(=O)Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl,,ClCCl,,c1ccncc1,,test
US06008230,C1OCOCO1.Cc1ccc([N+](=O)[O-])c2[nH]ccc(=O)c12>>Cc1ccc([N+](=O)[O-])c2[nH]cc(CO)c(=O)c12,,C1COCCO1,,Cl,,test
US20130157999A1,C1COCCN1.COc1cc(C(=O)O)c(C)cc1[N+](=O)[O-]>>COc1cc(C(=O)N2CCOCC2)c(C)cc1[N+](=O)[O-],,ClCCl,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050192294A1,BrBr.COc1cccc(C)c1-n1nc(C(C)(C)C)cc1N>>COc1cccc(C)c1-n1nc(C(C)(C)C)c(Br)c1N,,CC(=O)O,O,,,test
US20050131015A1,COC(=O)CN1C(=O)C(NC(=O)c2cc3cc(Cl)sc3[nH]2)Cc2ccccc21.NN>>NNC(=O)CN1C(=O)C(NC(=O)c2cc3cc(Cl)sc3[nH]2)Cc2ccccc21,,CCO,,O,,test
US05071866,COC(=O)CSCCCCCCn1nc(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1.O=S([O-])OO>>COC(=O)CS(=O)(=O)CCCCCCn1nc(-c2ccccc2)c(-c2ccccc2)c1-c1ccccc1,,CO,,O,,test
US20070055072A1,CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C>>CC(O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(O)CC[C@]4(C)[C@H]3CC[C@]12C,,CO,,[BH4-].[Na+],,test
US20060287363A1,CN1CCC(=O)CC1.ClCCl.Nc1cccc(NC(=O)c2ccc(F)cc2Cl)c1>>CN1CCC(Nc2cccc(NC(=O)c3ccc(F)cc3Cl)c2)CC1.Cl.Cl,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04927822,CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](CCCCN)C(=O)N1N=C(C(C)(C)C)S[C@H]1C(=O)O.Cl>>CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](CCCCN)C(=O)N1N=C(C(C)(C)C)S[C@H]1C(=O)O.Cl,,C1CCOC1,,O,,test
US20150038438A1,COC(=O)c1c(O)c2c(n(Cc3ccc(OC)cc3OC)c1=O)-c1cc3cc(CO[Si](C)(C)C(C)(C)C)n(C)c3cc1C=CC2.OCc1ccccc1>>COC(=O)c1c(OCc2ccccc2)c2c(n(Cc3ccc(OC)cc3OC)c1=O)-c1cc3cc(CO[Si](C)(C)C(C)(C)C)n(C)c3cc1C=CC2,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050215578A1,CSc1nsc(Cl)n1.OCc1ccccc1>>CSc1nsc(OCc2ccccc2)n1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US04337265,CC(=O)c1c2cccccc-2[nH]c1=O.CCOC(=O)CBr>>CCOC(=O)Cn1c2cccccc-2c(C(C)=O)c1=O,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20140323303A1,COC1=C(c2c(Cl)cc(Br)cc2Cl)C(=O)/C(=C/c2ccccn2)C1>>COC1=C(c2c(Cl)cc(Br)cc2Cl)C(=O)C(Cc2ccccn2)C1,[Zn],CC(=O)O,CCOC(C)=O,,,test
US20110152297A1,COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1O[C@H]1CCN(C(=O)OC(C)(C)C)[C@H](C(N)=O)C1>>COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1O[C@H]1CCN[C@H](C(N)=O)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110230458A1,CCOC(=O)C1CCN(C(=O)OC(C)(C)C)CC1=O>>CC(C)(C)OC(=O)N1CCC(CO)C(O)C1,,C1CCOC1,CO,[BH4-].[Na+],,test
US20160166560A1,COc1cc(CN2CCC(N(C)C(=O)n3cnc(-c4ccc(O)cc4)c3)CC2)ccc1F.NS(=O)(=O)Cl>>COc1cc(CN2CCC(N(C)C(=O)n3cnc(-c4ccc(OS(N)(=O)=O)cc4)c3)CC2)ccc1F,,CC(=O)N(C)C,,,,test
US05037990,NCCc1ccc([N+](=O)[O-])cc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=[N+]([O-])c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20030092677A1,CC(C)(C)OC(=O)Nc1ccc(-c2ccccc2)cc1N.CC1(C)OC(=O)C=C(c2cccs2)O1>>O=C1CC(c2cccs2)=Nc2ccc(-c3ccccc3)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120004270A1,BrCc1ccccc1.CC(C)(C)OC(=O)N1[C@H](C(O)C(F)(F)F)COC1(C)C>>CC(C)(C)OC(=O)N1[C@H]([C@@H](OCc2ccccc2)C(F)(F)F)COC1(C)C,,CN(C)C=O,,[H-].[Na+],,test
US05972964,CCCN(CCC)CC1CCc2ccc(NC(C)=O)cc21>>c1ccc2c(c1)CCC2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20030008768A1,Brc1ccc2c(c1)OCO2.Cc1ccccc1B(O)O>>Cc1ccccc1-c1ccc2c(c1)OCO2,,Cc1ccccc1,,[F-].[K+],,test
US20120202785A1,Cc1c(F)ccc([N+](=O)[O-])c1F.Nc1ccccn1>>Cc1c(F)ccc([N+](=O)[O-])c1Nc1ccccn1,,C1CCOC1,O,CC(C)(C)[O-].[K+],,test
US20160000760A1,CSC(NC#N)Nc1cc(F)c(-c2ccc(S(C)(=O)=O)cc2)c(Cl)c1.NN>>CS(=O)(=O)c1ccc(-c2c(F)cc(Nc3n[nH]c(N)n3)cc2Cl)cc1,,CCO,,,,test
US20030100579A1,C1=C(c2c[nH]c3ccccc23)CCNC1.Cc1ccc(S(=O)(=O)OCC2CCc3ccccc3O2)cc1>>C1=C(c2c[nH]c3ccccc23)CCN(CC2CCc3ccccc3O2)C1,,CCOC(C)=O,CS(C)=O,CCN(CC)CC,,test
US20100190825A1,CCCO[C@H]1CC[C@@H](N2CCC(Nc3cc(C)c(Cl)cc3[N+](=O)[O-])CC2)CC1>>CCCO[C@@H]1CC[C@H](N2CCC(Nc3cc(C)c(Cl)cc3N)CC2)CC1,[Ni],CCO,,NN,O,test
US20060167264A1,N#CCN.O=S(=O)(Cl)c1cnccc1C(F)(F)F>>N#CCNS(=O)(=O)c1cnccc1C(F)(F)F,,C1COCCO1,Cl,,,test
US20130331605A1,CCC(=O)O.CCCO.CO>>CCCOC.COCO,,CCCO,,,,test
US04673746,COC(Cl)Cl.COc1cccc(OC)c1Cl.O>>COc1ccc(C=O)c(OC)c1Cl,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20150126523A1,COC(=O)c1ccc(Br)c(CC(F)(F)F)c1>>OCc1ccc(Br)c(CC(F)(F)F)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US07071175B1,CCOC(=O)C(CSC(C)=O)Cc1ccc(NC(=O)OC(C)(C)C)nc1>>CCOC(=O)C(CSC(C)=O)Cc1ccc(N)nc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020002190A1,COC(=O)C(CC1CCCC1)c1ccc(N2CCOCC2)cc1>>O=C(O)C(CC1CCCC1)c1ccc(N2CCOCC2)cc1,,C1CCOC1,,[Li+].[OH-],,test
US20090111840A1,O=C(O)c1cnco1.c1ncn2c1CCCC21CCNC1>>O=C(c1cnco1)N1CCC2(CCCc3cncn32)C1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US05254655,C=CCBr.O=[N+]([O-])c1ccc(NCCO)cc1>>C=CCN(CCO)c1ccc([N+](=O)[O-])cc1,,CN1CCCC1=O,,,,test
US20030073850A1,CN(C)S(=O)(=O)n1cnc(C(=O)c2cccc([N+](=O)[O-])c2CO)c1>>CN(C)S(=O)(=O)n1cnc(C2OCc3c2cccc3[N+](=O)[O-])c1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20080070896A1,NCCNS(=O)(=O)c1ccccc1[N+](=O)[O-].O=S(=O)(Cl)CCCl>>O=[N+]([O-])c1ccccc1S(=O)(=O)NCCNS(=O)(=O)CCCl,,ClCCl,,CCN(CC)CC,,test
US05627215,BrCC1CC1.CC(C)(C)OC(=O)NCCCN(C/C=C/CN(CCCNC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.CCCCCC>>CC(C)(C)OC(=O)N(C/C=C/CN(CCCN(CC1CC1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)CCCN(CC1CC1)C(=O)OC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US06103718,COc1ccc(Br)cc1OC1CCCC1.O=C1OC(=O)[C@H]2CCCC[C@@H]12>>COc1ccc(C(=O)[C@H]2CCCC[C@H]2C(=O)O)cc1OC1CCCC1,,C1CCOC1,O,[Li]CCCC,[Cl-].[NH4+],test
US20160222033A1,CCN.COC(=O)c1ncsc1C(F)(F)F>>CCNC(=O)c1ncsc1C(F)(F)F,,CCO,,,,test
US20070203136A1,O=C(O)Cc1ccc2c(c1)CCO2.O=C1CCC(=O)N1Br>>BrCc1ccc2occc2c1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20040242608A1,COC(=O)c1ccc(C)c(N2C(=O)CC(=O)N=C2C)c1.Fc1ccc(CBr)c(F)c1>>COC(=O)c1ccc(C)c(-n2c(C)nc(OCc3ccc(F)cc3F)cc2=O)c1,C1COCCOCCOCCOCCOCCO1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140148576A1,CC(C)(C)OC(=O)NCC(S)CCC(NC(=O)OC(C)(C)C)C(=O)O.CSS(C)(=O)=O>>CSSC(CCC(NC(=O)OC(C)(C)C)C(=O)O)CNC(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20150266834A1,BrCc1ccccc1.C[C@@](O)(C(=O)O)C(F)(F)F>>C[C@@](O)(C(=O)OCc1ccccc1)C(F)(F)F,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20120009226A1,COC(=O)c1c(O)c2c(Cl)cccc2n(C)c1=O>>Cn1c(=O)c(C(=O)O)c(O)c2c(Cl)cccc21,,CC(=O)O,,,,test
US04983619,CC(C)(C)c1ccc(-c2ccoc2C(=O)[O-])cc1>>CC(C)(C)c1ccc(-c2ccoc2C(=O)O)cc1,,C1CCOC1,O,[Na+].[OH-],,test
US20100197683A1,CCCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(C2CCC(O)CC2)c2ncnn12.CI>>CCCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(C2CCC(OC)CC2)c2ncnn12,,CCOC(C)=O,,CN(C)C=O,[H-].[Na+],test
US04812464,ClC(=NN=Cc1cccnc1)c1cccnc1.S>>c1cncc(C2=NNC(c3cccnc3)S2)c1,,CCO,,[K+].[OH-],,test
US20040235905A1,O=c1c(-c2cccc(F)c2)coc2cc(O)ccc12>>Oc1ccc2c(c1)OCC(c1cccc(F)c1)C2,[Pd],CCO,,,,test
US20080242694A1,CC(C)(C)OC(=O)NCC(CN=[N+]=[N-])Cc1ccccc1.CC(C)(C)OC(=O)NCC(CO)Cc1ccccc1.CS(=O)(=O)Cl.[N-]=[N+]=[N-]>>Cl.NCC(Cc1ccccc1)Cc1[nH]nnc1-c1ccc2cnccc2c1,,ClCCl,,CCN(CC)CC,,test
US20090312338A1,OC(c1c(Cl)cnc2[nH]ccc12)C1CCC1>>O=C(c1c(Cl)cnc2[nH]ccc12)C1CCC1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20010051631A1,Cl.O=C1c2cnc3cccc(n23)CN1CC1CCN(C(=O)C(F)(F)F)CC1>>Cl.O=C1c2cnc3cccc(n23)CN1CC1CCN(C(=O)C(F)(F)F)CC1,,CCO,,,,test
US04638067,CCOC(=O)c1cn(CC)c2cc(-c3nc(CN=[N+]=[N-])cs3)c(F)cc2c1=O>>CCOC(=O)c1cn(CC)c2cc(-c3nc(CN)cs3)c(F)cc2c1=O,[Pd],CC(=O)O,,[H][H],,test
US20130217680A1,C=Cc1ccc2c(c1)CC(C)OC2=O.O=C(OO)c1cccc(Cl)c1>>CC1Cc2cc(C3CO3)ccc2C(=O)O1,,ClCCl,O,,,test
US20090247567A1,CN(C)C=C(C(=O)c1cc2c(s1)-c1ccc(Br)cc1OCC2)c1ccccc1Cl.NN>>Clc1ccccc1-c1c[nH]nc1-c1cc2c(s1)-c1ccc(Br)cc1OCC2,,CO,,,,test
US03943148,CI.c1ccc2c3c([nH]c2c1)C1CCCN1CC3>>Cn1c2c(c3ccccc31)CCN1CCCC21,,CN(C)C=O,,[H-].[Na+],,test
US20110230486A1,CC(=O)Nc1cc(C)c(C(C)=O)c(Cl)c1>>CC(=O)c1c(C)cc(N)cc1Cl,,CCO,,Cl,[Na+].[OH-],test
US04025505,Cc1ccc([N+](=O)[O-])cc1N1C(=O)c2cc(Cl)ccc2C(C)C1=O>>Cc1ccc(N)cc1N1C(=O)c2cc(Cl)ccc2C(C)C1=O,[Ni],CCOC(C)=O,,,,test
US20160272622A1,Cc1c(C(=O)O)cnn1C(C)(C)C.O=C(Cl)C(=O)Cl>>Cc1c(C(=O)Cl)cnn1C(C)(C)C,,C1CCOC1,,CN(C)C=O,,test
US05344845,C=CCOC(=O)C1(C)CCC(OC(=O)/C=C/c2ccc(OC(C)=O)c(OC)c2)CC1>>C=CCOC(=O)C1(C)CCC(OC(=O)/C=C/c2ccc(O)c(OC)c2)CC1,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US04587049,CCOC(=O)C1(C(=O)OCC)CC(=O)N1Cc1ccc(OC)cc1OC>>CCOC(=O)C1CC(=O)N1Cc1ccc(OC)cc1OC,,CS(C)=O,,O,[Cl-].[Na+],test
US20040048897A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(Cl)c(S(=O)(=O)N2CCNCC2)c1O>>CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2c(Cl)ccc(N)c2O)CC1,,ClCCl,,,,test
US20140094462A1,CCOCCN.C[C@@H]1[C@@H](c2ccccc2)OC(=O)CCC=CC[C@@H](CC(=O)O)C(=O)N1C>>CCOCCNC(=O)C[C@@H]1CC=CCCC(=O)O[C@H](c2ccccc2)[C@@H](C)N(C)C1=O,,ClCCl,,CO,,test
US20090105214A1,CC1(C)NC(=O)c2ccc(F)cc2O1.CI>>CN1C(=O)c2ccc(F)cc2OC1(C)C,,C1CCOC1,,[H-].[Na+],,test
US20050080105A1,BrCC1CO1.COc1ccc(Cl)cc1C1=C(S)C(=O)NC2C=CC(C(F)(F)F)=CC12>>COc1ccc(Cl)cc1C1=C(SCC2CO2)C(=O)NC2C=CC(C(F)(F)F)=CC12,,CCO,,[Na+].[OH-],,test
US05674886,N#Cc1ccccc1F.Nn1cnnc1>>N#Cc1ccccc1Nn1cnnc1,,CS(C)=O,O,Cl,CC(C)(C)[O-].[K+],test
US04362728,CN=C=S.NS(=O)(=O)C(F)(F)F>>CNC(=S)NS(=O)(=O)C(F)(F)F,,CC(C)=O,O,[Na+].[OH-],,test
US04536518,COc1ccc(C2(O)CCCc3ccccc32)cc1>>COc1ccc(C2=CCCc3ccccc32)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20140323468A1,Brc1cncc(C2CCCN2)c1.CS(=O)(=O)Cl>>CS(=O)(=O)N1CCCC1c1cncc(Br)c1,,ClCCl,,c1ccncc1,,test
US20110245242A1,COc1cc(NC(=O)CCCCl)cc([N+](=O)[O-])c1>>COc1cc(N2CCCC2=O)cc([N+](=O)[O-])c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US06018046,COc1cc2c(=O)c(Cc3cncc(C)c3)cn3c4cc(Br)ccc4c(c1)c23>>Cc1cncc(Cc2cn3c4cc(Br)ccc4c4cc(O)cc(c2=O)c43)c1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US04283328,Br.O=C(CNC(=O)OCc1ccccc1)NC(=Cc1ccccc1)C(=O)O>>Br.NCC(=O)NC(=Cc1ccccc1)C(=O)O,,CC(=O)O,,CC(=O)OC(C)=O,,test
US04329495,C=C(Cc1ccc(Cl)cc1)C(=O)O.OC(=S)c1ccccc1>>O=C(SCC(Cc1ccc(Cl)cc1)C(=O)O)c1ccccc1,,ClC(Cl)Cl,,ClCCl,,test
US20120142672A1,ClCCCBr.O=C(O)Cc1ccc(F)cc1F>>O=C(O)C(CCCCl)c1ccc(F)cc1F,,C1CCOC1,,[Li]CCCC,,test
US20110105761A1,CCCCCCBr.CCc1ccc(-n2ccnc2)c(C(=O)O)c1>>CCCCCCn1cc[n+](-c2ccc(CC)cc2C(=O)O)c1.[Br-],,C1CCOC1,,,,test
US20150175604A1,Cc1cc2c(ccc3nnc(C)n32)[nH]1.O=[N+]([O-])c1cccc(CCl)c1>>Cc1cc2c(ccc3nnc(C)n32)n1Cc1cccc([N+](=O)[O-])c1,,CN(C)C=O,,[H-].[Na+],,test
US20120202788A1,CC(C)O.NC(N)=S.O=[N+]([O-])c1cccc(Cl)c1-c1nc2c(F)cncc2s1.O=[N+]([O-])c1cccc(Cl)c1C(Cl)=Nc1c(F)cncc1F.c1ccncc1>>Cc1cc(Nc2ncc(F)c3nc(-c4c(Cl)cccc4C#N)sc23)ncn1,,CC(C)O,,CCN(CC)CC,,test
US20160016908A1,CC(=O)Cl.CC(C)[C@@H]1Nc2ccccc2[C@H](NC(=O)OCc2ccccc2)[C@H]1C>>CC(=O)N1c2ccccc2[C@H](NC(=O)OCc2ccccc2)[C@@H](C)[C@@H]1C(C)C,,ClCCl,,c1ccncc1,,test
US05952306,CCOC(=O)[C@H](CNC(=O)CNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccccc1>>CCOC(=O)[C@H](CNC(=O)CN)NS(=O)(=O)c1ccccc1,[Pd],CCO,,,,test
US20070219261A1,CCOC(=O)CCNc1ccc(Cl)cc1C(=O)N(CCc1cccc(C(F)(F)F)c1)Cc1ccc(C(C)(C)C)cc1>>CC(C)(C)c1ccc(CN(CCc2cccc(C(F)(F)F)c2)C(=O)c2cc(Cl)ccc2NCCC(=O)O)cc1,,CCO,,[Na+].[OH-],,test
US20150266881A1,CC(C)(C)OC(=O)NC1CC1c1cccc(C(=O)O)c1.Nc1ccc(-c2ncccn2)cc1>>CC(C)(C)OC(=O)N[C@@H]1C[C@H]1c1cccc(C(=O)Nc2ccc(-c3ncccn3)cc2)c1,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110020460A1,CCOC(=O)c1cnn(C2CCN(C(=O)OC(C)C)CC2)c1Br>>CC(C)OC(=O)N1CCC(n2ncc(CO)c2Br)CC1,,C1CCOC1,CCOC(C)=O,CO,[Na+].[OH-],test
US04933355,OCc1csc(N2CCCCC2)n1>>O=Cc1csc(N2CCCCC2)n1,,CS(C)=O,,CCN(CC)CC,,test
US20130253186A1,OCC1CCN(c2ncc(C3=CCOCC3)c(OC3CN(c4ccc5ccccc5n4)C3)n2)CC1>>OCC1CCN(c2ncc(C3CCOCC3)c(OC3CN(c4ccc5ccccc5n4)C3)n2)CC1,[Pd],CO,,,,test
US20140350019A1,CCOC(=O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1C>>Cc1c(OCC(=O)O)ccc(F)c1NCc1cc(-c2cccc(F)c2)ccc1F,,C1CCOC1,,[Na+].[OH-],,test
US20040138251A1,CN1CCNCC1.N#Cc1cnc2cc(-c3ccc(C=O)cc3)sc2c1Nc1ccc(Oc2ccccc2)cc1>>CN1CCN(Cc2ccc(-c3cc4ncc(C#N)c(Nc5ccc(Oc6ccccc6)cc5)c4s3)cc2)CC1,CC(=O)O,CN(C)C=O,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US06358931B1,CN(C)S(=O)(=O)n1c(C=CC#N)cnc1[Si](C)(C)C(C)(C)C>>CN(C)S(=O)(=O)n1c(CCCN)cnc1[Si](C)(C)C(C)(C)C,O=[Pt],C1CCOC1,CCO,ClC(Cl)Cl,,test
US20020022605A1,CS(=O)(=O)Nc1cc(C(=O)CCl)ccc1OCc1ccccc1.c1ccc(CNCc2ccccc2)cc1>>CS(=O)(=O)Nc1cc(C(=O)CN(Cc2ccccc2)Cc2ccccc2)ccc1OCc1ccccc1,,CN(C)C=O,,,,test
US20130102776A1,CC(C)(C)OC(=O)N1CCN(Cc2c(O)ccc3c2OCC3=O)CC1.O=Cc1c[nH]c2c([N+](=O)[O-])cccc12>>CC(C)(C)OC(=O)N1CCN(Cc2c(O)ccc3c2O/C(=C\c2c[nH]c4c([N+](=O)[O-])cccc24)C3=O)CC1,C1CCNCC1,CO,,,,test
US20110245205A1,Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C3=CCSCC3)s2)c1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc(C3CCSCC3)s2)c1,[Pd],CCOC(C)=O,,,,test
US20150189880A1,CCSc1cccnc1C(=O)N(C)c1ccc(C(F)(F)F)cn1.O=C(OO)c1cccc(Cl)c1>>CCS(=O)(=O)c1cccnc1C(=O)N(C)c1ccc(C(F)(F)F)cn1,,ClC(Cl)Cl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US04965396,CCOC(=O)CC(=O)c1cc(F)c(F)cc1[N+](=O)[O-].CCOC([O-])[O-]>>CCOC=C(C(=O)OCC)C(=O)c1cc(F)c(F)cc1[N+](=O)[O-],,CC(=O)O,,,,test
US20160194328A1,CC(C)(C)OC(=O)NCCCCCCNCCCn1c(Sc2cc(Cl)cc(Cl)c2)nc2c(N)ncnc21>>NCCCCCCNCCCn1c(Sc2cc(Cl)cc(Cl)c2)nc2c(N)ncnc21,,ClCCl,O=C(O)C(F)(F)F,,,test
US20090105219A1,CCOC(=O)CBr.COC(=O)CC1CNc2cccc([N+](=O)[O-])c21>>CCOC(=O)CN1CC(CC(=O)OC)c2c1cccc2[N+](=O)[O-],,CC(C)=O,,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US20110207728A1,CO.O=C(Cn1cccc1C(=O)C(Cl)(Cl)Cl)c1ccc(C(F)(F)F)cn1>>COC(=O)c1cccn1CC(=O)c1ccc(C(F)(F)F)cn1,,O,,Cl,[Na+].[OH-],test
US20130261128A1,Cc1cc(OCC(C)(C)C(=O)O)ncc1-c1ccc(-c2nc(C(F)(F)F)cn2COCC[Si](C)(C)C)nc1>>Cc1cc(OCC(C)(C)C(=O)O)ncc1-c1ccc(-c2ncc(C(F)(F)F)[nH]2)nc1,,O,O=C(O)C(F)(F)F,[Na+].[OH-],,test
US20150038438A1,CCOC(=O)CCCBr.Sc1cccc(Br)c1>>CCOC(=O)CCCSc1cccc(Br)c1,,CN(C)C=O,,[H-].[Na+],,test
US05223498,CI.NC(=S)Nc1ccccc1N1CCOSC1>>CSC(=N)Nc1ccccc1N1CCOSC1,,CC(C)=O,,,,test
US20070249847A1,CCOC(=O)CNC(=O)c1cc(OC(F)(F)F)ccc1[N+](=O)[O-]>>O=C(O)CNC(=O)c1cc(OC(F)(F)F)ccc1[N+](=O)[O-],,COC(C)(C)C,,O,[Na+].[OH-],test
US06156758,CC(C)(C)OC(=O)c1ccc(NC2CCNCC2)cc1.O=S(=O)(Cl)c1ccc2ccccc2c1>>CC(C)(C)OC(=O)c1ccc(NC2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)cc1,,ClCCl,,CCN(CC)CC,,test
US20140187542A1,COc1ccc2ncc(=O)n(CC[C@@H]3COC(C)(C)O3)c2n1>>COc1ccc2ncc(=O)n(CC[C@@H](O)CO)c2n1,,C1CCOC1,,Cl,,test
US04057559,CI.N#CCC1CCCCCC1=O>>CC1(CC#N)CCCCCC1=O,,c1ccccc1,,Cc1ccccc1,,test
US20160152561A1,COc1cc(F)ccc1O.NS(=O)(=O)c1cccc(NC(=O)c2c(F)cccc2C(F)(F)F)c1>>COc1cc(F)ccc1Oc1cccc(C(F)(F)F)c1C(=O)Nc1cccc(S(N)(=O)=O)c1,,CN1CCCC1=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US04187316,COC(=O)C1=CC(NC(=O)OC(C)(C)C)CC=C1.Cl>>Cl.NC1C=C(C(=O)O)C=CC1,,CO,O,[Na+].[OH-],,test
US20090306066A1,CN(C)C(=O)[C@@H]1CCCCN1C(=O)OCc1ccccc1.Cl>>CN(C)C(=O)[C@@H]1CCCCN1.Cl,,CO,,,,test
US20130217666A1,CC(C)[Si](C#CC1(O)CCN(C)C1)(C(C)C)C(C)C>>C#CC1(O)CCN(C)C1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130197026A1,BrCCCCBr.Cc1ccc(S(=O)(=O)c2cc3ccccc3[nH]2)cc1>>Cc1ccc(S(=O)(=O)c2cc3ccccc3n2CCCCBr)cc1,,CN(C)C=O,,[K+].[OH-],,test
US04380638,ClCc1csc(=NC2NCCN2)[nH]1.NCCS>>NCCSCc1csc(=NC2NCCN2)[nH]1,,Cl,,,,test
US04221814,CC(C)C(=O)Cl.Nc1ccc(C(=O)O)c(NC(=O)c2ccc(C(=O)O)cc2)c1>>CC(C)C(=O)Nc1ccc(C(=O)O)c(NC(=O)c2ccc(C(=O)O)cc2)c1,,O,c1ccncc1,[Na+].[OH-],,test
US08193207B2,Cc1cc([N+](=O)[O-])cnc1Cl.O=C1N([C@@H]2CC[C@H](O)CC2)CCC12CCNCC2>>Cc1cc([N+](=O)[O-])cnc1N1CCC2(CC1)CCN([C@@H]1CC[C@H](O)CC1)C2=O,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US07034147B2,CCOC(=O)CCCCCOc1ccc(C2OC3C(CN=[N+]=[N-])OC(n4ccc(=O)[nH]c4=O)C3O2)cc1>>[N-]=[N+]=NCC1OC(n2ccc(=O)[nH]c2=O)C2OC(c3ccc(OCCCCCC(=O)O)cc3)OC12,,CCO,O,Cl,[Na+].[OH-],test
US04910201,O=c1c(Cl)c(Cl)cnn1-c1ccc(C(F)(F)F)cc1.OCc1ccc(Cl)cc1>>O=c1c(Cl)c(OCc2ccc(Cl)cc2)cnn1-c1ccc(C(F)(F)F)cc1,,CN(C)C=O,,[K+].[OH-],,test
US07452906B2,NO.O=C1CCc2cc(-c3cc(CO)oc3-c3ccncc3)ccc21>>OCc1cc(-c2ccc3c(c2)CCC3=NO)c(-c2ccncc2)o1,,CCO,,,,test
US20100022515A1,CC(C)OC(=O)N1CCC(C#N)CC1.NO>>CC(C)OC(=O)N1CCC(C(N)=NO)CC1,,CCO,,,,test
US20130079338A1,C[Si](C)(C)CCOCCl.O=c1[nH]c2ccc(O)cc2o1>>C[Si](C)(C)CCOCn1c(=O)oc2cc(O)ccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090176786A1,CNc1ccc(SC(F)(F)F)cc1Cl.O=C=NC(=O)c1c(F)cccc1F>>CN(C(=O)NC(=O)c1c(F)cccc1F)c1ccc(SC(F)(F)F)cc1Cl,,CCOCC,,,,test
US20110213003A1,C[C@@H](NC(=O)c1cc2ccccc2o1)c1cc(C(=O)O)on1.NOC1CCCCO1>>C[C@@H](NC(=O)c1cc2ccccc2o1)c1cc(C(=O)NO)on1,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20120184557A1,CSc1nc(N(C)c2ccccc2)n2ncc(C(C)C)c2n1.NCc1ccc(-c2ccccc2)cc1>>CSc1nc(NCc2ccc(-c3ccccc3)cc2)n2ncc(C(C)C)c2n1,,CO,,,,test
US20060025432A1,CN(C)C(=O)[C@@H]1CCCN1.NS(N)(=O)=O>>CN(C)C(=O)[C@@H]1CCCN1S(N)(=O)=O,,C1COCCO1,,CCN(CC)CC,Cl,test
US20130005707A1,C[Si](C)(C)C#N.[O-][n+]1ccc(Br)cc1>>N#Cc1cc(Br)ccn1,,CC#N,,CCN(CC)CC,,test
US20040039176A1,O=C(O)CCCS.c1ccc(SSc2ccccn2)nc1>>O=C(O)CCCSSc1ccccn1,,CCO,,CC(=O)O,,test
US20040121964A1,CC(C)(C)OC(=O)NC1CCN(c2ccccn2)CC1>>NC1CCN(c2ccccn2)CC1,,C1COCCO1,,Cl,,test
US05256799,COP(=O)(OC)OC.Oc1ccc2c(c1)NCC2>>CN1CCc2ccc(O)cc21,,ClCCl,,,,test
US20160096827A1,N#Cc1cc(Br)ccc1O[C@H]1CCNCC1(F)F.O=CO>>N#Cc1cc(Br)ccc1O[C@H]1CCN(C=O)CC1(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04801595,NC1CCN(CCc2c[nH]c3ccccc23)CC1.O=C(O)c1ccnc2ccccc12>>O=C(NC1CCN(CCc2c[nH]c3ccccc23)CC1)c1ccnc2ccccc12,,C1CCOC1,,CC(C)COC(=O)Cl,CCN(CC)CC,test
US05637780,C=C(C)C.OCc1ccc(CCl)cc1>>CC(C)(C)OCc1ccc(CCl)cc1,,ClCCl,O,O=S(=O)(O)O,[Na+].[OH-],test
US20150291549A1,N#Cc1c(Cl)cccc1C(=O)O>>N#Cc1c(Cl)cccc1CO,,C1CCOC1,,,,test
US20050267100A1,COc1ccc(N(C(=O)CN2C(=O)C(=Cc3c[nH]c4cc(F)ccc34)c3nnc(-c4ccccc4)n3-c3ccccc32)C(C)C)cn1>>COc1ccc(N(C(=O)CN2C(=O)C(Cc3c[nH]c4cc(F)ccc34)c3nnc(-c4ccccc4)n3-c3ccccc32)C(C)C)cn1,[Pd],CO,,O=C[O-].[NH4+],,test
US20040171099A1,ClCCBr.N#Cc1nc2ccc(O)cc2s1>>N#Cc1nc2ccc(OCCCl)cc2s1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04584293,COc1cc2c(cc1OC)CC(N(C)CCCNC(=O)Cc1cc(Cl)c(Cl)cc1N)CC2>>COc1cc2c(cc1OC)CC(N(C)CCCNCCc1cc(Cl)c(Cl)cc1N)CC2,,C1CCOC1,,Cc1ccccc1,,test
US06552022B1,COc1cccc(C(=O)Nc2ccc(N3CCNCC3)cc2)c1-c1ccc(C(C)C)cc1.NC(=O)CBr>>COc1ccc(-c2ccc(C(C)C)cc2)c(C(=O)Nc2ccc(N3CCN(CC(N)=O)CC3)cc2)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090062366A1,COC(=O)[C@@H]1CC[C@@H](C(=O)O)CC1.C[C@H](c1cccc2ccccc12)N(C[C@H]1CNC[C@@H]1c1ccccc1)C(=O)OC(C)(C)C.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COC(=O)[C@@H]1CC[C@@H](NC(=O)N2C[C@H](c3ccccc3)[C@@H](CN(C(=O)OC(C)(C)C)[C@H](C)c3cccc4ccccc34)C2)CC1,,Cc1ccccc1,,CCN(CC)CC,,test
US20150166549A1,BrP(Br)Br.CC(O)c1oc(=O)c2ccccc2c1-c1cccc(S(=O)(=O)N2CCOCC2)c1>>CC(Br)c1oc(=O)c2ccccc2c1-c1cccc(S(=O)(=O)N2CCOCC2)c1,,ClCCl,,CN(C)C=O,,test
US20060035938A1,CCOC=CC=C(C(=O)OCC)C(=O)OCC.Cc1cccc(N)c1>>CCOC(=O)C(=CC=CNc1cccc(C)c1)C(=O)OCC,,CCO,,,,test
US20140031349A1,CC1=C(N2CCC3(CCN(C(=O)OC(C)(C)C)CC3O)C2=O)COC1=O.CI>>COC1CN(C(=O)OC(C)(C)C)CCC12CCN(C1=C(C)C(=O)OC1)C2=O,O=[Ag],CC#N,,,,test
US20120172333A1,CCOC(=O)c1c(NC(=O)Cc2ccccc2F)cc(Cl)n1-c1ccc(OC)cc1>>COc1ccc(-n2c(Cl)cc3[nH]c(=O)c(-c4ccccc4F)c(O)c32)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20060084645A1,CC(=O)c1cccc(B(O)O)c1.FC(F)(F)Oc1ccc(Nc2cc(Cl)nc(N3CCOCC3)n2)cc1>>CC(=O)c1cccc(-c2nc(Cl)cc(Nc3ccc(OC(F)(F)F)cc3)n2)c1,,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20030191155A1,COc1ccc(C(=O)Cl)cc1.COc1ccc(NN=C(N)C(F)(F)F)cc1>>COc1ccc(-c2nc(C(F)(F)F)nn2-c2ccc(OC)cc2)cc1,,C1COCCO1,,c1ccncc1,,test
US20050272794A1,CC1(C)OB(c2ccc3cc(Cl)ccc3c2)OC1(C)C>>OB(O)c1ccc2cc(Cl)ccc2c1,,CC(C)=O,,Cl,,test
US20040082561A1,C1CN2CCN1CC2.COc1ccc(C2C(CCC(O)c3ccc(F)cc3)C(=O)N2c2ccc(OCc3ccc(CBr)cc3)cc2)cc1>>COc1ccc(C2C(CCC(O)c3ccc(F)cc3)C(=O)N2c2ccc(OCc3ccc(C[N+]45CCN(CC4)CC5)cc3)cc2)cc1.[Br-],,Cc1ccccc1,,,,test
US20080015184A1,CC(C)(C)OC(=O)NCCCCNc1c(N)cnc2cccnc12.CCN(CC)CC.O.O=C(Cl)CCl>>CC(C)(C)OC(=O)NCCCCn1c(CCl)nc2cnc3cccnc3c21.[NH4+].[OH-],,ClCCl,O,ClCCCl,,test
US20060025601A1,C1=Cc2ccccc2C1.CCOCC.O=C(Cl)C(Cl)(Cl)Cl>>O=C1CC2c3ccccc3CC12,[Zn],CCOCC,,,,test
US20130064770A1,ClCCCCBr.O=C1CNC(=O)N1>>O=C1CNC(=O)N1CCCCCl,,CN(C)C=O,,Cl,[H-].[Na+],test
US20140024650A1,COc1ccc(B(O)O)c(F)c1.Clc1ccc(Br)nc1>>COc1ccc(-c2ccc(Cl)cn2)c(F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20070099944A1,O=[N+]([O-])c1ccc2[nH]nc(Nc3cccc(F)c3)c2c1>>Nc1ccc2[nH]nc(Nc3cccc(F)c3)c2c1,[Pd],CO,,,,test
US05998459,CC(=O)NC(C(C)=O)c1ccccc1F.N#CCC#N>>Cc1c(-c2ccccc2F)[nH]c(N)c1C#N,,CO,,O,[K+].[OH-],test
US20060094752A1,CCC(=O)CBr.NC(=O)CCc1ccccn1>>CCc1cn2ccccc2c1CC(N)=O,,CC(C)=O,,,,test
US20090215843A1,CCOC(=O)CCCCC(CO)CCc1ccc(C#N)cc1>>CCOC(=O)CCCCC(C=O)CCc1ccc(C#N)cc1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20100137286A1,CCOC(=O)[C@@H]1CC[C@@H](Oc2ncccn2)CC1>>O=C(O)[C@@H]1CC[C@@H](Oc2ncccn2)CC1,,C1COCCO1,,[Na+].[OH-],,test
US03951981,O=C1Nc2ccc(Cl)cc2Nc2cscc21.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>S=C1Nc2ccc(Cl)cc2Nc2cscc21,,c1ccncc1,,,,test
US20070172421A1,CN.Cc1ccc(C=O)cc1C>>CN=Cc1ccc(C)c(C)c1,,CCO,,,,test
US04771058,CN.COC1=NS(=O)N=C1OC.Cc1cc(Br)cnc1NCCCN>>CNC1=NS(=O)N=C1NCCCNc1ncc(Br)cc1C,,CCO,CO,,,test
US06281218B1,CCOC(=O)Cl.COc1ccc(N)c([N+](=O)[O-])c1>>CCOC(=O)Nc1ccc(OC)cc1[N+](=O)[O-],,c1ccncc1,,,,test
US20160016927A1,CCC(=O)Cl.Nc1ccnc(Br)c1>>CCC(=O)Nc1ccnc(Br)c1,,CC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070117824A1,COC(=O)c1ccc(Cl)nc1.c1ccc(CN2CCC3(CCNC3)C2)cc1>>COC(=O)c1ccc(N2CCC3(CCN(Cc4ccccc4)C3)C2)nc1,,CS(C)=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20050113417A1,C=CC(=O)Cl.Nc1ccc(CO)cc1>>C=CC(=O)Nc1ccc(CO)cc1,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20100179109A1,CCc1cccc(-c2c(Cl)cccc2C(O)(CCCNC(=O)OC)[C@@H]2CCCN(C(=O)c3ccc(CN(C)C(=O)OC(C)(C)C)cc3CCC(N)=O)C2)c1>>CCc1cccc(-c2c(Cl)cccc2C(O)(CCCNC(=O)OC)[C@@H]2CCCN(C(=O)c3ccc(CNC)cc3CCC(N)=O)C2)c1,,CC#N,,Cl,,test
US20090137561A1,COC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(C(C)(C)C)c1.COc1ccc(F)c(B(O)O)c1>>COC(=O)c1ccc(-c2cc(OC)ccc2F)c(C(C)(C)C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20060135578A1,COc1cc(COc2nn(-c3ccccc3)cc2C=O)ccc1OCc1nc(-c2ccco2)oc1C.O=C1CSC(=O)N1>>COc1cc(COc2nn(-c3ccccc3)cc2/C=C2\SC(=O)NC2=O)ccc1OCc1nc(-c2ccco2)oc1C,,CCO,,C1CCNCC1,,test
US20150353553A1,Cc1cccnc1-c1ccccc1>>CC1CCCNC1c1ccccc1,O=[Pt]=O,CC(=O)O,,,,test
US20130261130A1,N#Cc1ccc(N)cc1.O=C(Cl)c1cccs1.O=C(O)c1ccc([N+](=O)[O-])c(C(=O)O)c1>>N#Cc1ccc(NC(=O)c2cc(C(=O)O)ccc2NC(=O)c2cccs2)cc1,,CN(C)C=O,ClCCl,O=S(Cl)Cl,,test
US20060172983A1,COC(=O)C(C)Oc1ccc(N=C=O)cc1.OCCO>>COC(=O)C(C)Oc1ccc(NC(=O)OCCO)cc1,,O,,,,test
US20110195954A1,CCC1Cc2ccccc2N1C(=O)c1cc(Cl)ncn1.COc1ccc2c(c1)CCN(C1CCNCC1)C(=O)N2>>CCC1Cc2ccccc2N1C(=O)c1cc(N2CCC(N3CCc4cc(OC)ccc4NC3=O)CC2)ncn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20110003862A1,C/C=C/C#N.NNc1cccc(C(F)(F)F)c1>>CC1CC(N)=NN1c1cccc(C(F)(F)F)c1,,CCO,,C,C[O-].[Na+],test
US20080097097A1,CCNC1(C(N)=O)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1>>CCNC1(C(N)=O)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1,,CC(C)=O,O,O=S(=O)(O)O,O=C([O-])[O-].[Na+].[Na+],test
US20150037280A1,CNCCO.Cc1c(C(=O)Nc2ccc(Oc3ccnc(NC(=O)Oc4ccccc4)c3)cn2)c(=O)n(-c2ccccc2)n1C>>Cc1c(C(=O)Nc2ccc(Oc3ccnc(NC(=O)N(C)CCO)c3)cn2)c(=O)n(-c2ccccc2)n1C,,CCOC(C)=O,O,CN1CCCC1=O,,test
US04980349,O=C(c1ccc(Cl)cc1Cl)c1cc([N+](=O)[O-])ccc1Cl>>Nc1ccc(Cl)c(C(=O)c2ccc(Cl)cc2Cl)c1,,CCOC(C)=O,,C,,test
US05047411,Cc1ccnc(N)c1.O=C(C=Cc1ccc([N+](=O)[O-])cc1)CBr>>Cc1ccn2cc(C=Cc3ccc([N+](=O)[O-])cc3)nc2c1,,CC#N,,,,test
US20040063691A1,CCOC(=O)C(OCC)OCC.SCCCS>>CCOC(=O)C1SCCCS1,,ClC(Cl)Cl,,CCOCC,FB(F)F,test
US20050113283A1,CC(=O)Nc1cc(-c2ccncc2)n[nH]1>>Nc1cc(-c2ccncc2)n[nH]1,,Cl,,,,test
US04477556,COc1cc(C=O)c([N+](=O)[O-])cc1OC>>COc1cc(CO)c([N+](=O)[O-])cc1OC,,CCO,,O,[BH4-].[Na+],test
US20100010015A1,CC(C)(C)O.N#Cc1ccc(I)c(C(=O)O)c1>>CC(C)(C)OC(=O)c1cc(C#N)ccc1I,CN(C)C=O,ClC(Cl)Cl,,O=S(Cl)Cl,c1ccncc1,test
US20080255092A1,Clc1ccc2c(c1CSc1nnc(NCC3CC3)s1)CCNCC2.O=C(O)CCC(=O)O>>Clc1ccc2c(c1CSc1nnc(NCC3CC3)s1)CCNCC2.O=C(O)CCC(=O)O,,CCO,,,,test
US20120101137A1,CC=O.CC[C@H](N)C(=O)OCc1ccccc1>>CCN[C@@H](CC)C(=O)OCc1ccccc1,,CO,,[Na+].[OH-],,test
US04388238,CCOC(N)=O.Nc1ccccc1>>CCOC(=O)Nc1ccccc1,,CCO,,,,test
US20030083238A1,COCCCCCCCOC1CCC2(CC1)OCCO2>>COCCCCCCCOC1CCC(=O)CC1,,C1CCOC1,,Cl,,test
US20090227588A1,CCOC(=O)C1CCN(c2cccc(C(=O)Nc3ccc(-n4nc(-c5cccnc5)cc4C(F)(F)F)nn3)c2)CC1>>O=C(Nc1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)nn1)c1cccc(N2CCC(C(=O)O)CC2)c1,,C1COCCO1,,O,[Li+].[OH-],test
US20020107278A1,CC(C)(C)OC(=O)N1CCc2c(n(CC(=O)O)c3ccc(Cl)c(Cl)c23)CC1.COc1ccc(N)cc1>>COc1ccc(NC(=O)Cn2c3c(c4c(Cl)c(Cl)ccc42)CCN(C(=O)OC(C)(C)C)CC3)cc1,CN(C)c1ccncc1,C1CCOC1,CCOC(C)=O,CC(C)N=C=NC(C)C,,test
US20120053171A1,N#CC(OCCO)c1cccc(Br)c1.O=S(Cl)Cl>>N#CC(OCCCl)c1cccc(Br)c1,,c1ccncc1,,O,,test
US20050130970A1,COc1ccc(CC(=O)Cl)cc1.ClCCl.NC(CO)C(=O)O>>COC(=O)C(CO)NC(=O)Cc1ccc(OC)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20130331372A1,CCOC(=O)c1cnn(-c2ccc(OC)c(F)c2)c1C(F)(F)F.O=C1CCC(=O)N1I>>CCOC(=O)c1cnn(-c2cc(F)c(OC)c(I)c2)c1C(F)(F)F,,CC(=O)O,,O=S(=O)(O)O,,test
US20120190654A1,COc1ccc(CN2Cc3c(Oc4ccc(N)nc4)ccnc3NC2=O)cc1.O=C(O)c1c[nH]cc(-c2ccc(F)cc2)c1=O>>COc1ccc(CN2Cc3c(Oc4ccc(NC(=O)c5c[nH]cc(-c6ccc(F)cc6)c5=O)nc4)ccnc3NC2=O)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04435387,CC(=O)OC[C@H]1O[C@H](O[C@H]2[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](Sc3ccc(NC(=O)c4cc(C(=O)Nc5ccc(S[C@@H]6O[C@H](COC(C)=O)[C@@H](O[C@H]7O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]7OC(C)=O)[C@H](OC(C)=O)[C@H]6OC(C)=O)cc5)cc(C(=O)Nc5ccc(S[C@@H]6O[C@H](COC(C)=O)[C@@H](O[C@H]7O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]7OC(C)=O)[C@H](OC(C)=O)[C@H]6OC(C)=O)cc5)c4)cc3)O[C@@H]2COC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>O=C(Nc1ccc(S[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)cc1)c1cc(C(=O)Nc2ccc(S[C@@H]3O[C@H](CO)[C@@H](O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)cc2)cc(C(=O)Nc2ccc(S[C@@H]3O[C@H](CO)[C@@H](O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)cc2)c1,,CO,,N,,test
US20080293770A1,Cc1cc(NC2CCN(C(=O)OC(C)(C)C)CC2)c([N+](=O)[O-])cc1C#N>>Cc1cc(NC2CCN(C(=O)OC(C)(C)C)CC2)c(N)cc1C#N,[Ni],CCO,,NN,O,test
US05504244,CCCCCCOC(=O)c1cccc(C(=O)c2ccc(C)cc2OCCCCCC)c1>>CCCCCCOc1cc(C)ccc1C(=O)c1cccc(C(=O)O)c1,,O,,[Na+].[OH-],,test
US20060041137A1,CCCC1=NNC(=O)/C1=C1/C=C(Sc2ccc(N)cc2)c2ccccc2N1.O=C(Cl)C1CCCC1>>CCCC1=NNC(=O)/C1=C1/C=C(Sc2ccc(NC(=O)C3CCCC3)cc2)c2ccccc2N1,,C1CCOC1,,,,test
US20110217311A1,CN[C@@H]1CC[C@@H](Oc2cc(F)ccc2[N+](=O)[O-])CC1.COC(=O)Cl>>COC(=O)N(C)[C@@H]1CC[C@@H](Oc2cc(F)ccc2[N+](=O)[O-])CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20150232460A1,COc1cccc(OC)c1C(=O)N(C1CCC1)[C@H]1CCC[C@@H]1NC(=O)OC(C)(C)C.Cl>>COc1cccc(OC)c1C(=O)N(C1CCC1)[C@H]1CCC[C@@H]1N.Cl,,CO,,C1COCCO1,,test
US20050107381A1,C=CC(C)=O.CCCC(NC1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cnc(Br)cn1>>CCCC(NC1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cnc(CCC(C)=O)cn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCC#N,,CCN(C(C)C)C(C)C,,test
US20100093724A1,C1COCCN1.CS(=O)(=O)c1cc([C@H](CC=O)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1>>CS(=O)(=O)c1cc([C@H](CCN2CCOCC2)NC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1,,CC(Cl)Cl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20050014749A1,Cc1noc(-c2ccccc2-c2ccc3c(c2)CCC[C@H]3NC(=O)OC(C)(C)C)n1>>Cc1noc(-c2ccccc2-c2ccc3c(c2)CCC[C@H]3N)n1,,C1COCCO1,CCOC(C)=O,Cl,,test
US20020146718A1,Nc1nc(Cl)c2[nH]cnc2n1.O=C(O)CBr>>Nc1nc(Cl)c2ncn(CC(=O)O)c2n1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20070213341A1,CC(C)(C)OC(=O)N1C(=O)C2(c3ccc(Cl)cc31)C(c1cccc(Cl)c1)CC(=O)NC2c1cc(F)ccc1CBr.CS(=O)(=O)N1CCNCC1>>CS(=O)(=O)N1CCN(Cc2ccc(F)cc2[C@H]2NC(=O)C[C@@H](c3cccc(Cl)c3)[C@]23C(=O)Nc2cc(Cl)ccc23)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04430455,C=CC(=O)OCC.CNCCCN(C)C>>CN(C)CCCN(C)CCCO,,CCOC(C)=O,CCOCC,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050054696A1,NNC(=O)c1cc2cc(Cl)ccc2[nH]1.O=C(O)C(=O)c1ccccc1>>O=C(NNC(=O)c1cc2cc(Cl)ccc2[nH]1)C(=O)c1ccccc1,,CN(C)C=O,O,ClCCCl,On1nnc2ccccc21,test
US20070135501A1,CCCCCCCOc1ccc(CC[C@](C)(CO)NC(=O)OC(C)(C)C)cc1.O=S(Cl)Cl>>CCCCCCCOc1ccc(CCC2(C)CO[S@@](=O)N2C(=O)OC(C)(C)C)cc1,,CC#N,CCOC(C)=O,Cl,c1ccncc1,test
US05332739,Cn1c(N2CCNCC2)cc(=O)n(C)c1=O.OCCCBr>>Cn1c(N2CCN(CCCO)CC2)cc(=O)n(C)c1=O,,CCO,,CCN(CC)CC,CCOCC,test
US20150119378A1,CC(C)(C)OC(=O)N1CC[C@H](O)C1.Oc1cc(Br)cnc1Cl>>CC(C)(C)OC(=O)N1CC(Br)=CC(O[C@@H]2CCNC2)=C1Cl,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150152108A1,O=C(NCc1ncc(-c2cccc(NC(=O)N3c4nc(-c5cccc(C(F)(F)F)c5)ccc4N4CC[C@H]3C4)c2)o1)OCc1ccccc1>>NCc1ncc(-c2cccc(NC(=O)N3c4nc(-c5cccc(C(F)(F)F)c5)ccc4N4CC[C@H]3C4)c2)o1,,CCOC(C)=O,,,,test
US04897420,O=C(O)CCCCCCc1ccc(O)cc1>>O=C(O)CCCCCC[C@@H]1CC[C@@H](O)CC1,,CCO,,CCOCC,,test
US20120277224A1,CCOC(CBr)OCC.NC(=O)c1ccc(C(=O)O)cc1>>O=C(O)c1ccc(-c2ncco2)cc1,,C1COCCO1,,,,test
US04732979,O=C1CCC2=C(CCc3cc(Cl)ccc32)N1>>Clc1ccc2c(c1)CCC1=C2CCCN1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20130196974A1,C=CC#N.OCc1ccccc1>>N#CCCOCc1ccccc1,,[Na+],[OH-],Cl,,test
US20150152048A1,CC(C)(C)OC(=O)N=C(NC(=O)OC(C)(C)C)n1cccn1.O=C(OCc1ccccc1)N1CCNCC1>>CC(C)(C)OC(=O)N=C(NC(=O)OC(C)(C)C)N1CCN(C(=O)OCc2ccccc2)CC1,,CO,,CCN(CC)CC,,test
US20100048568A1,C=CCBr.Nc1ccc(C(F)(F)F)cc1I>>C=CCNc1ccc(C(F)(F)F)cc1I,,O,,C1CCOC1,CC(C)(C)[O-].[K+],test
US20120101105A1,Cc1ccc(OCC2CC2)cn1.O=C(OO)c1cccc(Cl)c1>>OCc1ccc(OCC2CC2)cn1,,ClCCl,O,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20070135456A1,C=CCn1c(Cl)nc2c1c(=O)[nH]c(=O)n2COCC[Si](C)(C)C.CI>>C=CCn1c(Cl)nc2c1c(=O)n(C)c(=O)n2COCC[Si](C)(C)C,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20080161187A1,NCc1ccncc1.O=S(=O)(Cl)c1ccc(I)cc1>>O=S(=O)(NCc1ccncc1)c1ccc(I)cc1,,C1COCCO1,CCOCC,c1ccncc1,,test
US20160083361A1,BrCc1ccccc1.O=c1oc2c(C3OCCCO3)c(O)ccc2c2c1CNCC2>>O=Cc1c(O)ccc2c3c(c(=O)oc12)CN(Cc1ccccc1)CC3,,CN(C)C=O,,CCN(CC)CC,,test
US04435208,CCOC(=O)CC#N.O=Cc1cc(Oc2c(Cl)cc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]>>CCOC(=O)C(C#N)=Cc1cc(Oc2c(Cl)cc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-],,Cc1ccccc1,,C1CCNCC1,CC(=O)O,test
US20110144068A1,COc1ccc(Cn2cc(-c3ccnc(NC(C)(C)C)c3)c(-c3cccc([N+](=O)[O-])c3)n2)cc1>>COc1ccc(Cn2cc(-c3ccnc(NC(C)(C)C)c3)c(-c3cccc(N)c3)n2)cc1,[Zn],C1COCCO1,,O,[Cl-].[NH4+],test
US20160096827A1,COc1cc(Nc2ncnc(-c3ccc(O[C@H]4CCNCC4(F)F)c(C#N)c3)n2)ccc1N1CCN(C2COC2)CC1.C[C@H](O)C(=O)O>>COc1cc(Nc2ncnc(-c3ccc(O[C@H]4CCN(C(=O)[C@H](C)O)CC4(F)F)c(C#N)c3)n2)ccc1N1CCN(C2COC2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04824830,C=C1[C@@H]2OC23CC2OCCOC2[C@@H](C)[C@]3(C)[C@H]2CC[C@]3(C)C4OCCO[C@@]4(F)C[C@H]3[C@H]12.CI>>C=C1[C@@H](C)C2=CC(=O)C[C@@H](C)[C@]2(C)[C@H]2CC[C@]3(C)C(=O)[C@H](F)C[C@H]3[C@H]12,,CCOCC,c1ccccc1,[Mg],,test
US20080280836A1,CS(=O)(=O)NCCCc1ccc(N2C(=O)[C@H](CC[C@H](O)c3ccc(F)cc3)[C@H]2c2ccc(-c3ccc(C(O)(CO)CO)cc3)cc2OCc2ccccc2)cc1>>CS(=O)(=O)NCCCc1ccc(N2C(=O)[C@H](CC[C@H](O)c3ccc(F)cc3)[C@H]2c2ccc(-c3ccc(C(O)(CO)CO)cc3)cc2O)cc1,[Pd],CCO,,,,test
US20160016981A1,CCCCCCCCCCCCCCN(C)C.O=S1(=O)CCCCO1>>CCCCCCCCCCCCCC[N+](C)(C)CCCCS(=O)(=O)[O-],,CN(C)C=O,,,,test
US20110312936A1,CC(=O)c1ccccc1N.ClI>>CC(=O)c1cc(I)ccc1N,,Cl,,,,test
US20150232454A1,COc1cnc(Cl)nc1OC.N#Cc1ccc(B(O)O)cc1.c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>COc1cnc(-c2ccc(C#N)cc2)cc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US04073898,CSCC[NH3+].CSCC[NH3+].O=C([O-])CC(O)C(=O)[O-].OO>>CS(=O)CC[NH3+].CS(=O)CC[NH3+].O=C([O-])CC(O)C(=O)[O-],,CO,,,,test
US20150158851A1,CCOC(=O)C(=[N+]=[N-])C1(O)CCC(c2cnn(COCC[Si](C)(C)C)c2)CC1>>CCOC(=O)c1n[nH]c2c1CCC(c1cnn(COCC[Si](C)(C)C)c1)C2,,c1ccncc1,,O=P(Cl)(Cl)Cl,,test
US04452788,CCn1c(=O)c2[nH]c(-c3ccc(S(=O)(=O)O)cc3)nc2n(CC)c1=O.N>>CCn1c(=O)c2[nH]c(-c3ccc(S(N)(=O)=O)cc3)nc2n(CC)c1=O,,CN(C)C=O,,O=S(Cl)Cl,,test
US04369184,Cc1ccc(F)cc1CCl.[C-]#N>>Cc1ccc(F)cc1CC#N,,CCO,,O,,test
US20150210722A1,CC(C)(C)OC(=O)Nc1ccc(Oc2ccnc(Nc3cc(C#N)cc(OCCN4CCOCC4)c3)n2)c2ccccc12>>N#Cc1cc(Nc2nccc(Oc3ccc(N)c4ccccc34)n2)cc(OCCN2CCOCC2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Nc1ccc(N2CCOCC2)c(F)c1>>COc1ccc2nc(Nc3ccc(N4CCOCC4)c(F)c3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US05334716,CC(C)Cc1ccc(C(Cl)c2ccc(CC(C)C)cc2)cc1.CCOC(=O)CCCc1cc(C(=O)c2cccc(N)c2)c2ccccn12>>CCOC(=O)CCCc1cc(C(=O)c2cccc(NC(c3ccc(CC(C)C)cc3)c3ccc(CC(C)C)cc3)c2)c2ccccn12,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05843975,CCOC(=O)Cl.Cn1nc(N)c2ccc(OCc3ccccc3)cc21>>CCOC(=O)Nc1nn(C)c2cc(OCc3ccccc3)ccc12,,C1CCOC1,O,O=C([O-])O.[Na+],,test
US20120041004A1,Cc1c[nH]c2c(=O)n(C)c(=O)n(C)c12.O=C(CBr)Nc1nc(-c2cc(F)c(OCC(F)(F)F)c(Cl)c2)cs1>>Cn1c(=O)c2c(ccn2CC(=O)Nc2nc(-c3cc(F)c(OCC(F)(F)F)c(Cl)c3)cs2)n(C)c1=O,,CN(C)C=O,,[H-].[Na+],,test
US04781750,CCOC(=O)C(C(=O)N(C)C)=C(O)c1ccc(Cl)cc1Cl.O=C(Cl)c1ccccc1>>CCOC(=O)C(C(=O)N(C)C)=C(OC(=O)c1ccccc1)c1ccc(Cl)cc1Cl,,CCOCC,,CCN(CC)CC,,test
US20080096860A1,Fc1cccc(CBr)c1F.Oc1cc(O)nc(S)n1>>Oc1cc(O)nc(SCc2cccc(F)c2F)n1,,CC#N,O,CC(=O)[O-].[Na+],,test
US20150274705A1,C1CC2(CCC3(CC2)OCCO3)CN1>>O=C1CCC2(CCNC2)CC1,,CO,,Cl,,test
US20100093821A1,COc1ccc(-n2ncc(C(N)=O)c2N)cc1.[OH-]>>COc1ccc(-n2ncc(C(=O)O)c2N)cc1,,[Na+],[OH-],CCO,Cl,test
US20030087923A1,N#Cc1cnc(Cl)nc1N.Nc1ccc(C(=O)NCCCn2ccnc2)cc1>>N#Cc1cnc(Nc2ccc(C(=O)NCCCn3ccnc3)cc2)nc1N,,CN1CCCC1=O,O,,,test
US20140296203A1,CN1C[C@@H](c2ccccc2C(F)(F)F)[C@H]([N+](=O)[O-])C1>>CN1C[C@@H](N)[C@H](c2ccccc2C(F)(F)F)C1,[Zn],CO,,CC(=O)O,,test
US05011825,CC(=O)O.CC(=O)O.CC(=O)O.CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)OCc1ccccc1)C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C>>CC(=O)O.CC(=O)O.CC(=O)O.CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)OC(C)(C)C,,CC(=O)O,,,,test
US20100105744A1,CSCc1cc(F)cc2c(C(CCO)c3ccc(Cl)cc3)c[nH]c12.O=C(OO)c1cccc(Cl)c1>>CS(=O)Cc1cc(F)cc2c(C(CCO)c3ccc(Cl)cc3)c[nH]c12,,ClCCl,,,,test
US20120178963A1,C=Cc1ccccc1.CCC(C)=O.Cc1ccc(S(=O)(=O)O)cc1.OC1OC[C@@H](O)[C@H](O)[C@H]1O.Oc1ccccc1.c1ccc(P(c2ccccc2)c2cc3ccc2CCc2ccc(c(P(c4ccccc4)c4ccccc4)c2)CC3)cc1>>CC(C(=O)Oc1ccccc1)c1ccccc1.O=C(CCc1ccccc1)Oc1ccccc1,,CCC(C)=O,,[Cl-].[Li+],,test
US20140213586A1,COc1cc(N)cnc1OC.O=Cc1ccccc1>>COc1cc(N=Cc2ccccc2)cnc1OC,,CCO,,,,test
US20110300218A1,COc1ccccc1OCC(O)CN1CCN(CC(=O)Nc2c(C)cccc2C)CC1.O=C(O)/C=C/C(=O)O>>COc1ccccc1OCC(O)CN1CCN(CC(=O)Nc2c(C)cccc2C)CC1.O=C([O-])/C=C/C(=O)[O-],,CC(C)O,,,,test
US20080085895A1,Nc1nc2ccccc2c2c1nc1n2[C@@H](CO)COC1.O=S(Cl)Cl>>Nc1nc2ccccc2c2c1nc1n2[C@@H](CCl)COC1,,CC#N,,[Na+].[OH-],,test
US20120157430A1,COC(=O)/C=C/c1c(C)c(Cl)cc(C(C)NC(=O)OC(C)(C)C)c1OC.C[N+](=O)[O-]>>COC(=O)CC(C[N+](=O)[O-])c1c(C)c(Cl)cc(C(C)NC(=O)OC(C)(C)C)c1OC,,ClCCl,,C1CCC2=NCCCN2CC1,O,test
US20020156081A1,C1CCOC1.CCOC(=O)C1CCC(O)CC1.Nc1ncnc2[nH]nc(I)c12>>CCOC(=O)C1CCC(C2N=C(I)c3c(N)ncnc32)CC1,,C1CCOC1,O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100189658A1,CC(C)(C)OC(=O)N1CCN(CCCN=[N+]=[N-])CC1>>[N-]=[N+]=NCCCN1CCNCC1,,CO,ClCCl,O=C(O)C(F)(F)F,,test
US20150031685A1,CN(C(=O)OCc1ccccc1)[C@H](CN1CC[C@H](O[Si](C)(C)C(C)(C)C)C1)c1cccc(-c2ncon2)c1>>CNC(CN1CC[C@H](O)C1)c1cccc(-c2ncon2)c1,,Cl,,,,test
US20110144081A1,COC(=O)[C@@H]1CN(Cc2ccccc2)C[C@H]1c1ccc(Cl)cc1.NC=O>>NC(=O)[C@@H]1CN(Cc2ccccc2)C[C@H]1c1ccc(Cl)cc1,,CN(C)C=O,,C[O-].[Na+],,test
US20160251339A1,COc1ccc(S(=O)(=O)n2cc(C(F)F)c3ccc(Br)cc32)cc1C1CCN(C(=O)C(Cl)(Cl)Cl)CC1>>COc1ccc(S(=O)(=O)n2cc(C(F)F)c3ccc(Br)cc32)cc1C1CCNCC1,,C1CCOC1,,[K+].[OH-],,test
US20080103183A1,NC1(CNC2C3CC4(O)CC2CC(O)(C3)C4)CCCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=C1NC2(CCCC2)CN1C1C2CC3(O)CC1CC(O)(C2)C3,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20160102071A1,CC#C[C@@H](CC(=O)OCC)c1ccc(COc2ccc3scc(-c4c(C)cccc4C)c3c2)cc1>>CC#C[C@@H](CC(=O)O)c1ccc(COc2ccc3scc(-c4c(C)cccc4C)c3c2)cc1,,CCO,,Cl,[Li+].[OH-],test
US20120184542A1,COC(=O)c1ccc(Cl)c(NC(=O)c2cc3cnc(N4CCCCC4)nc3[nH]c2=O)c1>>O=C(O)c1ccc(Cl)c(NC(=O)c2cc3cnc(N4CCCCC4)nc3[nH]c2=O)c1,,CO,O,[Na+].[OH-],,test
US20160039808A1,CN(C)CCCO.Oc1nc(Cl)nc2cnccc12>>CN(C)CCCOc1nc(O)c2ccncc2n1,,C1COCCO1,,[H-].[Na+],,test
US04918080,C1CCOC1.CC(=O)O.Cc1ccc2ccccc2c1C(=O)/C=C/c1ncn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c1C.O>>Cc1ccc2ccccc2c1C(=O)CCc1nc[nH]c1C.O=C(O)/C=C\C(=O)O,,O,,,,test
US20160021883A1,C=C(C)c1ccc(C)cc1[N+](=O)[O-]>>Cc1ccc(C(C)C)c(N)c1,[Pd],CCOC(C)=O,,,,test
US20080234329A1,CC(=O)c1ccc(N2CCOCC2)cc1.COC(OC)N(C)C.NN>>c1cc(-c2ccc(N3CCOCC3)cc2)n[nH]1,,CO,,O,,test
US20140114068A1,O=C1c2ccccc2C(=O)C1(O)O.Oc1cccc2c1CCCC2>>O=C1c2ccccc2C2(O)Oc3c(ccc4c3CCCC4)C12O,,CC(=O)O,,,,test
US20050038247A1,CC(C)(C)C(=O)Nc1ccc(Br)cc1-c1ncccn1.O=[N+]([O-])O>>CC(C)(C)C(=O)Nc1c(-c2ncccn2)cc(Br)cc1[N+](=O)[O-],,O,O=C(O)C(F)(F)F,CO,,test
US20160213653A1,C=CC(=O)Nc1cccc(-c2cnc3c(c2)c(-c2ccnc(OC)c2)cn3S(=O)(=O)c2ccc(C)cc2)c1>>C=CC(=O)Nc1cccc(-c2cnc3[nH]cc(-c4ccnc(OC)c4)c3c2)c1,,C1COCCO1,,[Li+].[OH-],,test
US20060084815A1,CC(=O)Nc1cccc2c1C(=O)OC2=O.COc1ccc(C(N)C#N)cc1OC1CCCC1>>COc1ccc(C(C#N)N2C(=O)c3cccc(NC(C)=O)c3C2=O)cc1OC1CCCC1,,CC(=O)O,CCOC(C)=O,,,test
US20150274777A1,CCCC[C@H](NC(=O)OC(C)(C)C)C(=O)N(C)OC>>CCCC[C@@H](C=O)NC(=O)OC(C)(C)C,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20110160201A1,CCCCBr.CCOC(=O)C1CCNCC1>>CCCCC1(C(=O)OCC)CCNCC1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20140357614A1,CN1CCNCC1.O=c1cc(I)cn[nH]1>>CN1CCN(c2cn[nH]c(=O)c2)CC1,,CCO,,,,test
US05986108,CC(=O)O[C@H]1[C@@H](C(=O)[C@H](Cc2ccccc2)NC(=O)OCc2ccccc2)C(=O)N1N.CCOC(C)=O>>CC(=O)O[C@H]1[C@@H](C(=O)[C@H](Cc2ccccc2)NC(=O)CCc2ccccc2)C(=O)N1N,[Pd],CCOC(C)=O,,[H][H],,test
US20120157435A1,CC(=O)OC(C)=O.Nc1ccccc1C(F)(F)F>>CC(=O)Nc1ccccc1C(F)(F)F,,O,,,,test
US05254655,C=CCBr.CNc1cccc(O)c1>>C=CCN(C)c1cccc(O)c1,,CN1CCCC1=O,,,,test
US20080269220A1,BrC(c1ccccc1)c1ccccc1.COC(=O)c1ccc(O)c(CC(C)C)c1>>COC(=O)c1ccc(OC(c2ccccc2)c2ccccc2)c(CC(C)C)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100168188A1,O=C1C=C2c3ccc4nn(Cc5ccccc5)cc4c3CC2(CCF)CC1>>O=C1C=C2c3ccc4nn(Cc5ccccc5)cc4c3CC23CCC1C3,,CN(C)C=O,,[Cl-].[Li+],,test
US20130317023A1,Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F)c1ccccc1,,ClCCl,,c1ccncc1,,test
US04431815,O=[N+]([O-])c1cccc(Cn2ccnc2)c1>>Nc1cccc(Cn2ccnc2)c1,[Pd],CCO,,,,test
US20090082379A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1(C)CN(C(=O)CNC2CCCC2)c2cc(N3C(=O)N(Cc4ccnc(Cl)c4)C(C)(C)C3=O)ccc21>>CC(C)(C)OC(=O)N(CC(=O)N1CC(C)(C)c2ccc(N3C(=O)N(Cc4ccnc(Cl)c4)C(C)(C)C3=O)cc21)C1CCCC1,,ClCCl,,CCN(CC)CC,,test
US20140296200A1,CCOC(=O)C(=CN(C)C)n1cc(C#N)cn1.NNc1ccc(C(=O)NCc2ccccc2)cn1>>N#Cc1cnn(-c2cnn(-c3ccc(C(=O)NCc4ccccc4)cn3)c2O)c1,,CC(C)O,,CCN(C(C)C)C(C)C,Cl,test
US05081135,C=C1CC(C(=O)OCC)N(C=O)C(C(=O)OCC)(C(=O)OCC)C1>>C=C1CC(C(=O)OCC)N(C=O)C(C(=O)OCC)C1,,CS(C)=O,,O,[Cl-].[Na+],test
US20150353553A1,CN1CCNCC1.COC(=O)c1nc(N[C@H](CCCOS(C)(=O)=O)C2CCC2)c2c(n1)nc(-c1cccc(C)c1)n2Cc1ccc(C(F)(F)F)cc1>>COC(=O)c1nc(N[C@H](CCCN2CCN(C)CC2)C2CCC2)c2c(n1)nc(-c1cccc(C)c1)n2Cc1ccc(C(F)(F)F)cc1,,C1CCOC1,,,,test
US20070032515A1,COCCOc1cccc(-c2c(C)n[nH]c2N)c1OCCOC.O=Cc1ccc(O)cc1>>COCCOc1ccc2c(-c3ccc(O)cc3)nc3[nH]nc(C)c3c2c1OCCOC,,O=C(O)C(F)(F)F,,,,test
US20130150339A1,COc1ccc(CN(c2cscn2)S(=O)(=O)c2ccc3c(-c4ccc(C(F)(F)F)cc4OC)nccc3c2)cc1>>COc1cc(C(F)(F)F)ccc1-c1nccc2cc(S(=O)(=O)Nc3cscn3)ccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080076758A1,C[C@H]1CN(C(=O)OC(C)(C)C)CCN1S(C)(=O)=O.Cl>>C[C@H]1CNCCN1S(C)(=O)=O.Cl,,CCOCC,ClCCl,,,test
US20070299092A1,COCCOc1cc2ncnc(NC3=CC(=O)C(N4CC4C)=CC3=O)c2cc1OC.O>>COCCOc1cc2ncnc(NC3=CC(=O)C(NCC(C)O)=CC3=O)c2cc1OC,,Cl,O,C1CCOC1,,test
US20060264460A1,N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1.O=Cc1ccc(-n2ccnc2)cc1>>N#Cc1cnc2ccc(NCc3ccc(-n4ccnc4)cc3)cc2c1Nc1ccc(F)c(Cl)c1,,CCO,,[BH3-]C#N.[Na+],,test
US20140336106A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC1CC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1.O=C(O)C(F)(F)F>>C[C@H](N)C(=O)N[C@@H](CC1CC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US04544501,CC1(C)CN1P(=O)(Cl)N1CC1(C)C.CN(C)CCCN>>CN(C)CCCNP(=O)(N1CC1(C)C)N1CC1(C)C,,C1CCOC1,,,,test
US20140303140A1,CCc1nc2c(C)cc(N3CCN(C(=O)OC(C)(C)C)CC3)cn2c1N(C)c1nc(-c2ccc(F)cc2)c(C#N)s1>>CCc1nc2c(C)cc(N3CCNCC3)cn2c1N(C)c1nc(-c2ccc(F)cc2)c(C#N)s1,,CO,,CCOCC,Cl,test
US06110952,COc1ccc(N)c(C)c1[N+](=O)[O-].O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1ccc(NC(=O)C(F)(F)F)c(C)c1[N+](=O)[O-],,ClCCl,ClCCl,CCN(CC)CC,Cl,test
US20090005558A1,BrC(Br)(Br)Br.OCCc1ccc(OC(F)F)c(OC(F)F)c1>>FC(F)Oc1ccc(CCBr)cc1OC(F)F,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100087418A1,CC(C)(C)OC(=O)N1CCOc2c(cccc2C2CCCCC2)C1.Cl>>Cl.c1cc2c(c(C3CCCCC3)c1)OCCNC2,,CCOC(C)=O,,,,test
US20150094296A1,CCOC(=O)C(C)(C)n1cc(N)cn1.CSc1nccc(=O)[nH]1>>CCOC(=O)C(C)(C)n1cc(Nc2nccc(=O)[nH]2)cn1,,COCCOCCOC,,O,,test
US05399291,CCOCC(F)(F)C(F)(F)C(F)(F)CO.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOCC(F)(F)C(F)(F)C(F)(F)COS(=O)(=O)C(F)(F)F,,ClCCl,,CCN(CC)CC,O,test
US20160237090A1,Cc1nc(C2CC(=O)N(c3cnn4c3CN(C(=O)OC(C)(C)C)[C@@H](C)C4)C2)no1.O=C(Nc1cc(F)c(F)c(F)c1)Oc1ccccc1>>Cc1nc(C2CC(=O)N(c3cnn4c3CN(C(=O)Nc3cc(F)c(F)c(F)c3)[C@@H](C)C4)C2)no1,,ClCCl,O=C(O)C(F)(F)F,CCN(C(C)C)C(C)C,,test
US03988471,C=Cc1ccccc1.CC(C)(C)c1cc(C(=S)S)cc(C(C)(C)C)c1O>>CC(SC(=S)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)c1ccccc1,,Cc1ccccc1,,,,test
US20050032786A1,COC(=O)c1ccccc1S.N#Cc1cc(C2CCCN2C(=O)c2ccccc2)ccn1>>O=C(c1ccccc1)N1CCCC1c1ccnc(-c2nc(=O)c3ccccc3s2)c1,,Cc1ccccc1,,CCN(CC)CC,,test
US20100168080A1,COC(=O)c1cc(Cl)ccc1OCCCO.CS(=O)(=O)Cl>>COC(=O)c1cc(Cl)ccc1OCCCOS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US06599917B1,C#C[C@@]1(O)CN2CCC1CC2.Ic1ccc(N2CCC3(C2)OCCO3)nc1Cc1ccccc1>>O[C@]1(C#Cc2ccc(N3CCC4(C3)OCCO4)nc2Cc2ccccc2)CN2CCC1CC2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,,CCN(CC)CC,,test
US04053605,CC(C)(C)N1CC(COc2ncccc2C#N)OC1c1ccccc1.Cl>>CC(C)(C)NCC(O)COc1ncccc1C#N.Cl,,CCOCC,,,,test
US20090012010A1,COC(=O)c1cc(OC(C)C)cc(OC(C)C)c1>>CC(C)Oc1cc(OC(C)C)cc(C(=O)O)c1,,C1CCOC1,O,[Li]O,,test
US20060217372A1,COC(=O)CCc1ccc(O)cc1.NCc1ccccc1>>O=C(CCc1ccc(O)cc1)NCc1ccccc1,,Cl,,,,test
US20150038488A1,COc1ccc([C@@H](C)N2C[C@H]([C@@H](C)Oc3nc(Cl)cc4ncn(CCO[Si](C)(C)C(C)(C)C)c34)CC2=O)cc1>>C[C@@H](Oc1nc(Cl)cc2ncn(CCO)c12)[C@H]1CNC(=O)C1,,ClCCl,,CO,O=C(O)C(F)(F)F,test
US05258382,CCOC(=O)C1(n2cccc2C(=O)C(Cl)(Cl)Cl)CC(=O)NC1=O.O=S(=O)(Cl)Cl>>CCOC(=O)C1(n2cc(Cl)cc2C(=O)C(Cl)(Cl)Cl)CC(=O)NC1=O,,ClC(Cl)Cl,,O,,test
US04130658,CCCI.COc1cccc(CCNC(=O)Cc2cccc(OC)c2)c1>>CCCN(CCc1cccc(OC)c1)CCc1cccc(OC)c1,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20110294812A1,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCc3ccnc(NC(=O)C(C)(C)N(C)C(=O)OC(C)(C)C)c3)c3ccccc23)cc1>>CNC(C)(C)C(=O)Nc1cc(COc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)c3ccccc23)ccn1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20080004302A1,CCOC(=O)c1cc(CNc2nccc(Nc3cc(OC(C)C)n[nH]3)n2)on1.CN>>CNC(=O)c1cc(CNc2nccc(Nc3cc(OC(C)C)n[nH]3)n2)on1,,CN(C)C=O,CO,,,test
US20070232627A1,CC(C)c1ccc2c(Nc3cc(C(=O)Nc4ccc(Br)cn4)ccc3Sc3ccc(NC(=O)CCC(C)C4CCC5C6C(OC=O)CC7CC(OC=O)CCC7(C)C6CC(OC=O)C45C)cc3)ncnc2n1>>CC(C)c1ccc2c(Nc3cc(C(=O)Nc4ccc(Br)cn4)ccc3Sc3ccc(NC(=O)CCC(C)C4CCC5C6C(O)CC7CC(O)CCC7(C)C6CC(O)C45C)cc3)ncnc2n1,,CO,,[Na+].[OH-],,test
US20040102481A1,C=C[Sn](CCCC)(CCCC)CCCC.CN1C=CC(c2c[nH]c3c(Br)cc(OS(=O)(=O)c4ccccc4)cc23)=CC1>>C=Cc1cc(OS(=O)(=O)c2ccccc2)cc2c(C3CCN(C)CC3)c[nH]c12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCOC(C)=O,,test
US05958942,CCOC(=O)c1cccc2nc(C)cn12.O=C(Cl)C(Cl)(Cl)Cl>>CCOC(=O)c1cccc2nc(C)c(C(=O)C(Cl)(Cl)Cl)n12,CN(C)c1ccncc1,ClC(Cl)Cl,,,,test
US05599813,CC(C)CCl.CC1(C)OC(=O)CC(=O)O1.c1ccncc1>>CC(C)C(=O)CC(=O)OC(C)(C)C,,c1ccncc1,,ClCCl,,test
US20160002264A1,C=CC(=O)OC.C=CCC(OCC(OCC)OCC)C1CC1>>CCOC(COC(C/C=C/C(=O)OC)C1CC1)OCC,,ClCCl,,,,test
US20080207654A1,CCCc1nc(CC)n(-c2ccc(OC3CCCC(O)C3)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1>>CCCc1nc(CC)n(-c2ccc(OC3CCCC(=O)C3)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20160272617A1,CN.COC(=O)C(F)(F)C(F)(F)c1n[nH]c(-c2ccc(N)cc2)n1>>CNC(=O)C(F)(F)C(F)(F)c1n[nH]c(-c2ccc(N)cc2)n1,,C1CCOC1,,,,test
US20140206680A1,CC(C)(C)OC(=O)N[C@H]1COCC[C@H]1Nc1nc(Cl)c2c(c1F)CN(C(=O)OC(C)(C)C)C2=O.CCCC[Sn](CCCC)(CCCC)c1cc2c(s1)c(C)nn2C>>Cn1ncc2sc(-c3nc(N[C@@H]4CCOC[C@@H]4NC(=O)OC(C)(C)C)c(F)c4c3C(=O)N(C(=O)OC(C)(C)C)C4)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20070191604A1,COC(=O)C1CCN(CC(=O)N2CCN(c3ccc(-c4ncccn4)cc3)CC2)C1>>O=C(O)C1CCN(CC(=O)N2CCN(c3ccc(-c4ncccn4)cc3)CC2)C1,,CO,,Cl,[Li+].[OH-],test
US20040209921A1,COC(=O)c1cc(C#N)ccc1CN(Cc1ncccc1C)Cc1ncccc1C>>COC(=O)c1cc(CN)ccc1CN(Cc1ncccc1C)Cc1ncccc1C,[Ni],N,,,,test
US03956297,COC(CN)OC.Cc1ccc2c(c1)NC(=S)c1ccccc1N2>>COC(CNC1=Nc2cc(C)ccc2Nc2ccccc21)OC,,CCCCO,,,,test
US20020099089A1,COC(=O)c1ccccc1NC(=O)/C=C/c1ccc2cc(F)ccc2c1>>O=C(/C=C/c1ccc2cc(F)ccc2c1)Nc1ccccc1C(=O)O,,CO,,[Na+].[OH-],,test
US20160068512A1,Clc1ccc(C(c2ccc(Cl)cc2)c2ccc3ncnc(Cl)c3c2)cc1.NC1CCN(c2ccccc2)CC1>>Clc1ccc(C(c2ccc(Cl)cc2)c2ccc3ncnc(NC4CCN(c5ccccc5)CC4)c3c2)cc1,,CC(C)O,,,,test
US20150080364A1,CC(C)(C)OC(=O)N1CCNCC1.Cc1cc(C=O)n(C(C)C)n1>>Cc1cc(CN2CCN(C(=O)OC(C)(C)C)CC2)n(C(C)C)n1,,ClCCCl,,CCN(CC)CC,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20120088748A1,CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(Cl)c(Cl)c2)[C@H](CC(N)=O)C1.[OH-]>>CC(C)(C)OC(=O)N1CCO[C@@H](c2ccc(Cl)c(Cl)c2)[C@H](CC(=O)O)C1,,CCCCO,,Cl,,test
US20120029029A1,NC(=S)Nc1ccc(F)cc1.O=C(O)C(=O)CBr>>O=C(O)c1csc(Nc2ccc(F)cc2)n1,,CO,,,,test
US05965745,CN(C)C(=O)Cl.COc1cc(C(=O)O)ccc1Cc1c[nH]c2ccc(NC(=O)OC3CCCC3)cc12>>COc1cc(C(=O)O)ccc1Cc1cn(C(=O)N(C)C)c2ccc(NC(=O)OC3CCCC3)cc12,,CN(C)C=O,,[H-].[Na+],,test
US20160083349A1,O.O=Cc1cc2cc(Cl)c(OCc3ccccn3)cc2nc1Cl>>O=Cc1cc2cc(Cl)c(OCc3ccccn3)cc2[nH]c1=O,,Cl,,,,test
US20070197617A1,COP(=O)(COc1ccc([C@H]2NC(=O)N([C@H](C(=O)Nc3ccc(I)cc3F)[C@@H](C)c3ccccc3)C2=O)cc1)OC>>C[C@@H](c1ccccc1)[C@@H](C(=O)Nc1ccc(I)cc1F)N1C(=O)N[C@H](c2ccc(OCP(=O)(O)O)cc2)C1=O,,ClCCl,,C[Si](C)(C)Br,,test
US06071932,COc1ccc(C2(O)CCNCC2)cc1.OC(CCl)Cn1c2ccccc2c2ccccc21>>COc1ccc(C2(O)CCN(CC(O)Cn3c4ccccc4c4ccccc43)CC2)cc1.Cl,,CC(=O)CC(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20030232849A1,C1CN=C2NCCCN2C1.CC#N.CC(=O)O.CCOCCN1Cc2cc(Oc3ccc(O)cc3)ccc2C1=O.CO.COCCC1(Br)C(=O)NC(=O)NC1=O>>CC(C)OC(C)C.CCOCCN1Cc2cc(Oc3ccc(OC4(CCOC)C(=O)NC(=O)NC4=O)cc3)ccc2C1=O,,CC(=O)O,CO,,,test
US05106871,COCOc1cc(O)c(C(=O)CCc2ccc(OCOC)c(OCOC)c2)c(OCOC)c1>>O=C(CCc1ccc(O)c(O)c1)c1c(O)cc(O)cc1O,,CO,,Cl,,test
US06780870B2,CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nc(S(C)(=O)=O)n2)cc1.NCc1ccccn1>>CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nc(NCc3ccccn3)n2)cc1,,CC#N,,,,test
US05474994,COc1ccccc1N1CCNCC1.Cc1c(-c2ccccc2)oc2c(CS(=O)(=O)CCCl)cccc2c1=O>>COc1ccccc1N1CCN(CCS(=O)(=O)Cc2cccc3c(=O)c(C)c(-c4ccccc4)oc23)CC1.Cl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US06169107A,CCOC(=O)c1cc2c(C(F)(F)F)ccc(O)c2n1C.N#CCCl>>CCOC(=O)c1cc2c(C(F)(F)F)ccc(OCC#N)c2n1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130184254A1,NNc1ccc(F)cc1.O=Cc1c(I)ccnc1F>>Fc1ccc(-n2ncc3c(I)ccnc32)cc1,,CN1CCCC1=O,,,,test
US20140343052A1,CC(C)(C)N.COc1ccc(-c2cc(C)cc(C(=O)NS(C)(=O)=O)n2)c(C)c1C1C2=C(CC(C)(C)CC2=O)OC2=C1C(=O)CC(C)(C)C2>>CC(C)(C)N.COc1ccc(-c2cc(C)cc(C(=O)NS(C)(=O)=O)n2)c(C)c1C1C2=C(CC(C)(C)CC2=O)OC2=C1C(=O)CC(C)(C)C2,,CCO,,CCOCC,,test
US20110028502A1,Cc1cnn(-c2ccc(C)c([N+](=O)[O-])c2)c1>>Cc1cnn(-c2ccc(C)c(N)c2)c1,[Pd],CCO,,[H][H],,test
US20110294798A1,Cc1ccc2c(c1)C(=O)C(=O)N2.NNc1cc(N2CCOCC2)nc(OCCN2CCOCC2)n1>>Cc1ccc2c(c1)C(=NNc1cc(N3CCOCC3)nc(OCCN3CCOCC3)n1)C(=O)N2,CC(=O)O,CCO,,,,test
US20080227782A1,CNS(=O)(=O)c1cccc(CN)c1.Cc1nc(-c2ccc(F)cc2)ncc1C(=O)O>>CNS(=O)(=O)c1cccc(CNC(=O)c2cnc(-c3ccc(F)cc3)nc2C)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05547949,Clc1cc(NC23CC4CC(CC(C4)C2)C3)nc(Cl)n1.NC12CC3CC(CC(C3)C1)C2>>Clc1cc(NC23CC4CC(CC(C4)C2)C3)nc(NC23CC4CC(CC(C4)C2)C3)n1,,CCCCO,,,,test
US20090275537A1,CN(C(=O)OC(C)(C)C)C(COCc1ccccc1)COCC1COC(C)(C)O1>>CN(C(=O)OC(C)(C)C)C(CO)COCC1COC(C)(C)O1,[Pd],CO,,[H][H],,test
US05580866,CC(=O)N1CCSc2cccc(Cl)c2C1.O=C(OO)c1cccc(Cl)c1>>CC(=O)N1CCS(=O)c2cccc(Cl)c2C1,,ClCCl,,,,test
US20090124802A1,Cc1cc(C2CC2)cc(C)c1Oc1nc(Cl)nc2cc[nH]c12.N#Cc1ccc(N)cc1>>Cc1cc(C2CC2)cc(C)c1Oc1nc(Nc2ccc(C#N)cc2)nc2cc[nH]c12,,O,,O=C(O)C(F)(F)F,,test
US20120028939A1,Cc1ccc(S(=O)(=O)N2C(=O)N([C@H](C)c3ccccc3)C[C@@H]2C(=O)O[C@@H]2C[C@H](C)CC[C@H]2C(C)C)cc1>>C[C@H](c1ccccc1)N1C[C@H](CO)NC1=O,,C1CCOC1,,[H-].[Na+],,test
US20130303533A1,Cc1cc(N)n[nH]1.Cn1ncc2c(Br)nc(C(F)(F)c3ccc(F)cn3)nc21>>Cc1cc(Nc2nc(C(F)(F)c3ccc(F)cn3)nc3c2cnn3C)n[nH]1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20090029958A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCCOCCc1ccccc1>>Cc1ccc(S(=O)(=O)OCCOCCc2ccccc2)cc1,,c1ccncc1,,,,test
US20090054483A1,CC(=O)Cl.CCC(O)(CC)c1nnc(N)o1>>CCC(O)(CC)c1nnc(NC(C)=O)o1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20120245124A1,CC(C)[C@@H](N=Cc1nc(-c2ccc(C(F)(F)F)cc2)ccc1F)C(C)O>>CC(C)[C@@H](NCc1nc(-c2ccc(C(F)(F)F)cc2)ccc1F)C(C)O,[Ni],C1CCOC1,,[H][H],,test
US20110172230A1,Nc1cnccn1.O=C(Cl)Oc1ccccc1>>O=C(Nc1cnccn1)Oc1ccccc1,,c1ccncc1,,,,test
US20150174099A1,CC#CCBr.CCOC(=O)CC(=O)OCC>>CC#CCC(C(=O)OCC)C(=O)OCC,,C1CCOC1,,Cl,[H-].[Na+],test
US20150336986A1,Cn1c(=O)c2c(-c3ccccc3)[nH]c(C(c3nc(Cl)cs3)C(C)(C)COS(C)(=O)=O)c2n(C)c1=O>>Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1nc(Cl)cs1)C(C)(C)C3,,C1CCOC1,,[H-].[Na+],,test
US20130281452A1,CCS(=O)(=O)c1cc(N2CCOCC2)cc(C)c1C#N.O=S(=O)(O)O>>CCS(=O)(=O)c1cc(N2CCOCC2)cc(C)c1C(N)=O,,O,,N,,test
US20020169317A1,CC(C)(C)OC(=O)N1CCNCC1.ClCCOc1cccc2c1c1cccc3c1n2C(c1ccccc1)CO3>>CC(C)(C)OC(=O)N1CCN(CCOc2cccc3c2c2cccc4c2n3C(c2ccccc2)CO4)CC1,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20100087427A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1C[C@H](CN(Cc2cccc(CN)c2)c2ccc(Cl)cc2)[C@@H](Cc2ccccc2)C1>>CC(=O)NCc1cccc(CN(C[C@H]2CN(C(=O)OC(C)(C)C)C[C@@H]2Cc2ccccc2)c2ccc(Cl)cc2)c1,,CCO,O,O=C([O-])O.[Na+],,test
US20090023745A1,CC(C)(C)OC(=O)c1ccc(N2CCN(C(=O)C(F)(F)F)CC2)cc1[N+](=O)[O-]>>O=C(O)c1ccc(N2CCN(C(=O)C(F)(F)F)CC2)cc1[N+](=O)[O-],,ClCCl,,,,test
US20120142668A1,C[C@@H](C(=O)N[C@H](/C=C/C(=O)n1ccc2ccccc21)CCc1ccccc1)N(C(=O)[O-])C(C)(C)C.O=C(O)C(F)(F)F>>C[C@H](N)C(=O)N[C@H](/C=C/C(=O)n1ccc2ccccc21)CCc1ccccc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20160024077A1,C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OC)c(C)cn3nc(-c4cccc(-c5ccc(F)cc5O)c4)cc23)CC1.C=CC[C@@H](C)O>>C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OC)c(C)cn3nc(-c4cccc(-c5ccc(F)cc5O[C@@H](C)CC=C)c4)cc23)CC1,,C1CCOC1,O,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110294836A1,CC(C)(C)OC(=O)N1CCC(c2cccc(COc3ccc(-n4cnnn4)cc3F)n2)CC1.Cl>>Cl.Fc1cc(-n2cnnn2)ccc1OCc1cccc(C2CCNCC2)n1,,CO,ClCCl,,,test
US03978071,CCOC(=O)Cc1ccc(C(=O)CCl)cc1.Nc1ccccn1>>CCOC(=O)Cc1ccc(-c2cn3ccccc3n2)cc1,,CCOCC,,CCO,,test
US20120165304A1,CC(=O)CCl.CC(C)(C)OC(=O)N1CC(C(N)=S)C1>>Cc1csc(C2CN(C(=O)OC(C)(C)C)C2)n1,,CO,,,,test
US20150274704A1,CC(C)(C)OC(=O)N1CC(N)C2(CCCC2)C1.Clc1ccnc(Cl)n1>>CC(C)(C)OC(=O)N1CC(Nc2ccnc(Cl)n2)C2(CCCC2)C1,,CCO,,CCN(CC)CC,,test
US20150239900A1,CC(C)(C)OC(=O)N1CCNCC1.Clc1cc2c(Cl)cnnc2cc1Br>>CC(C)(C)OC(=O)N1CCN(c2cnnc3cc(Br)c(Cl)cc23)CC1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20030195210A1,CCOc1ccccc1-c1nc2c(C3CCCC3)nc(C)n2c(=O)[nH]1.O=S(=O)(O)Cl>>CCOc1ccc(S(=O)(=O)Cl)cc1-c1nc2c(C3CCCC3)nc(C)n2c(=O)[nH]1,,ClCCl,,,,test
US20130317065A1,COc1ccc2c(Cc3cccc(C(=O)NN)n3)c(-c3ccccc3)[nH]c2c1.O=C(n1ccnc1)n1ccnc1>>COc1ccc2c(Cc3cccc(-c4n[nH]c(=O)o4)n3)c(-c3ccccc3)[nH]c2c1,,C1CCOC1,,Cl,,test
US20100168430A1,O=C(Nc1ccc(Oc2ccnc3[nH]ncc23)cc1)Nc1ccc(Oc2ccc(F)cc2)c(C(F)(F)F)c1.O=CC=O>>O=C1N(c2ccc(Oc3ccnc4[nH]ncc34)cc2)C(O)C(O)N1c1ccc(Oc2ccc(F)cc2)c(C(F)(F)F)c1,,CCO,,[Na+].[OH-],,test
US20020016337A1,CC(C)(C)OC(=O)N1CCCC(CNc2ccccc2)C1.O=C(Cl)c1cccs1>>CC(C)(C)OC(=O)N1CCCC(CN(C(=O)c2cccs2)c2ccccc2)C1,,ClCCl,,,,test
US20050245518A1,Nc1ccccc1NC(=O)c1ccc(N2CC[C@H](Sc3ccccn3)C2)cc1.O=C(OO)c1cccc(Cl)c1>>Nc1ccccc1NC(=O)c1ccc(N2CC[C@H]([S@](=O)c3ccccn3)C2)cc1,,ClCCl,,,,test
US03984412,CCCCNc1c(N)c(N)nc(C)c1C(=O)OCC.O=CC=O>>CCCCNc1c(C(=O)OCC)c(C)nc2nccnc12,,O,,Cc1ccccc1,,test
US20050203089A1,COc1ccc(Cl)cc1[C@]1(F)C(=O)N(CO)c2cc(C(F)(F)F)ccc21.ClP(Cl)Cl>>COc1ccc(Cl)cc1[C@]1(F)C(=O)N(CCl)c2cc(C(F)(F)F)ccc21,,ClCCl,,,,test
US20070197636A1,O=[N+]([O-])c1cc(O)c(F)cc1C(F)(F)F>>Nc1cc(O)c(F)cc1C(F)(F)F,[Ni],C1CCOC1,,[H][H],,test
US05866576,CC(C)=CCC[C@H](C)CCBr.Cn1cnc2c1c(=O)[nH]c(=O)n2C>>CC(C)=CCC[C@H](C)CCn1c(=O)c2c(ncn2C)n(C)c1=O,,CS(C)=O,,O,[H-].[Na+],test
US20020099212A1,Cc1nc(=O)c2ccc(C(N)=O)cc2n1Cc1ccc(Cl)cc1Cl.O=S(=O)(O)O>>Cc1nc(=O)c2ccc(C(=O)O)cc2n1Cc1ccc(Cl)cc1Cl,,O,,,,test
US05369098,Cc1ccc(S(=O)(=O)OC2CC(CO)C2)cc1.Nc1ncnc2nc[nH]c12>>Nc1ncnc2c1ncn2[C@@H]1C[C@H](CO)C1,,CN(C)C=O,,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US20060009434A1,CC(=O)Oc1cc2c(cc1I)[C@H]1CC[C@]3(C)C(=O)CC[C@H]3[C@@H]1[C@@H](OC(C)=O)C2>>C[C@]12CC[C@@H]3c4cc(I)c(O)cc4C[C@H](O)[C@H]3[C@@H]1CCC2=O,,CO,,C[O-].[Na+],,test
US20040138251A1,CN1CCNCC1.COc1cc(Nc2c(C#N)cnc3cc(-c4csc(C=O)c4)sc23)c(Cl)cc1Cl>>COc1cc(Nc2c(C#N)cnc3cc(-c4csc(CN5CCN(C)CC5)c4)sc23)c(Cl)cc1Cl,CC(=O)O,CN(C)C=O,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20060004003A1,CCOC(=O)/C=C/c1c(COC)nc2c(cnn2CC)c1-c1cncc(C)c1>>CCOC(=O)CCc1c(COC)nc2c(cnn2CC)c1-c1cncc(C)c1,O=[Pt],CCO,,,,test
US20150051225A1,C#C[Si](C)(C)C.CC1(C)CC(=O)CC(C)(C)O1>>CC1(C)CC(O)(C#C[Si](C)(C)C)CC(C)(C)O1,,C1CCOC1,,[Li]CCCC,,test
US04588719,CCO.NN.O=C1c2ccccc2C(=O)N1C1CCCc2ccccc21>>CN(C)C1(OCCCN)CCCc2ccccc21,,CCO,,O,,test
US20090076032A1,CC1(C)CC(=O)OC1=O.CC1(C)[C@@H](O[C@H]2O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]2O[C@@H]2O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]2O)CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@@](C)(C(=O)O)CC[C@]3(C)CC[C@]21C>>CC(C)(CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2C(=O)C=C2[C@@H]4C[C@@](C)(C(=O)O)CC[C@]4(C)CC[C@]23C)C1(C)C)C(=O)O,CN(C)c1ccncc1,c1ccncc1,,Cl,,test
US20100160288A1,Cc1nc(N2CCN(C)CC2)c2nc(-c3ccccc3Cl)n(C3CCOCC3)c2n1.O=P(O)(O)O>>Cc1nc(N2CCN(C)CC2)c2nc(-c3ccccc3Cl)n(C3CCOCC3)c2n1.O=P(O)(O)O,,CCO,,,,test
US20120232056A1,COC(=O)c1ccc2nc(-c3cc4ccccc4s3)c(N3CCCCCC3)nc2c1>>O=C(O)c1ccc2nc(-c3cc4ccccc4s3)c(N3CCCCCC3)nc2c1,,CO,O,Cl,[Na+].[OH-],test
US05436343,COC(=O)C1(CCC(OC)OC)CCCC1>>COC(CCC1(CO)CCCC1)OC,,CCOCC,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20100190763A1,NC1CC1.O=C(O)c1ccc(N2CCN(Cc3cnc4c(c3)NC(=O)[C@@H]3CCCN43)CC2)nc1>>O=C(NC1CC1)c1ccc(N2CCN(Cc3cnc4c(c3)NC(=O)[C@@H]3CCCN43)CC2)nc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120202852A1,CO.COC(=O)C(C)(C)n1cc([C@H](NS(=O)C(C)(C)C)c2ccc(OCC(F)(F)F)cn2)nn1.Cl>>COC(=O)C(C)(C)n1cc([C@@H]([NH3+])c2ccc(OCC(F)(F)F)cc2)nn1.[Cl-],,CO,,CCOCC,,test
US04046889,CC(=O)SCCC(=O)N1CCC[C@H]1C(=O)O>>O=C(O)[C@@H]1CCCN1C(=O)CCS,,N,,,,test
US03984403,O=C([O-])c1cc[n+](CC2=CN3C(=O)C(NC(=O)C(c4ccccc4)S(=O)(=O)O)[C@H]3SC2)cc1>>O=C([O-])c1cc[n+](CC2=CN3C(=O)C(NC(=O)C(c4ccccc4)S(=O)(=O)O)[C@H]3SC2)cc1,,O,,[Na],,test
US04826866,CCOC(=O)C(Cl)C(C)=O.Cl.NNC(=S)NC1CC1>>CCOC(=O)c1c(NC2CC2)n[nH]c1C.Cl,,Cl,,,,test
US05245085,C=C[Mg]Br.CC(=O)CCC=C(C)CCC=C(C)COC1CCCCO1>>C=CC(C)(O)CCC=C(C)CCC=C(C)COC1CCCCO1,,C1CCOC1,,[Cl-].[NH4+],,test
US20090169558A1,CCOC(=O)c1cc(-c2ccnc(Cl)c2)[nH]c1N.N=CN>>O=c1[nH]cnc2[nH]c(-c3ccnc(Cl)c3)cc12,,CCCCO,,Cl,O=C([O-])O.[Na+],test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCCCS(C)(=O)=O.Oc1ccc2[nH]c(C(F)(F)F)cc2c1>>COc1cc2c(Oc3ccc4[nH]c(C(F)(F)F)cc4c3)ncnc2cc1OCCCS(C)(=O)=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090227601A1,COC(CNC(=O)[C@@H](CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccc(C)cc1)OC>>Cc1ccc(S(=O)(=O)N2C=CNC(=O)[C@H]2CC(=O)OC(C)(C)C)cc1,,C1COCCO1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05863911,CCO.O=C(O)C[c-]1cccc1.[Fe+2].c1cc[cH-]c1>>CCOC(=O)C[c-]1cccc1.[Fe+2].c1cc[cH-]c1,,CCO,,O=S(=O)(O)O,,test
US20040242884A1,CCOC(=O)c1c[nH]c2c(C)c(C=O)sc2c1=O.CI>>CCOC(=O)c1cn(C)c2c(C)c(C=O)sc2c1=O,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20040106604A1,Br.O=C1CC(Cc2ccccc2)CO1>>O=C(O)CC(CBr)Cc1ccccc1,,CC(=O)O,,,,test
US20120252778A1,CCOC(=O)c1c(C)nn(-c2ccc(Cc3c(CC)nn4c(C)cc(C)nc34)cc2)c1N>>CCOC(=O)c1cn(-c2ccc(Cc3c(CC)nn4c(C)cc(C)nc34)cc2)nc1C,,C1CCOC1,,CC(C)CCON=O,,test
US20100240729A1,CCC(=O)OC.COC=O.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)/C(C)=C/OS(=O)(=O)c1ccc(C)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20100298339A1,Nc1cccc(-c2cccc3nc(Nc4ccc(OCCN5CCCC5)cc4)nn23)c1.O=C(O)Cc1cccc(Cl)c1>>O=C(Cc1cccc(Cl)c1)Nc1cccc(-c2cccc3nc(Nc4ccc(OCCN5CCCC5)cc4)nn23)c1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140249129A1,CS(=O)(=O)c1cc(C#N)ccc1[C@H]1NC(=O)N(c2cccc(C(F)(F)F)c2)C2=C1C(=O)CCC2.N#CCI>>CS(=O)(=O)c1cc(C#N)ccc1[C@@H]1C2=C(CCCC2=O)N(c2cccc(C(F)(F)F)c2)C(=O)N1CC#N,,C1CCOC1,O,[H-].[Na+],,test
US20070299069A1,COc1ccc2c(C#N)cn(C3CC3)c2c1>>N#Cc1cn(C2CC2)c2cc(O)ccc12,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20150353505A1,CC1(C)CO1.COC(=O)c1n[nH]c2ccc(F)cc12>>CC(C)(O)Cn1nc(C(=O)O)c2cc(F)ccc21,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130090353A1,Fc1cnccc1-c1cc2cc(C(F)(F)F)ccc2o1.OCC(F)F>>FC(F)COc1cnccc1-c1cc2cc(C(F)(F)F)ccc2o1,,O,,CN(C)C=O,[H-].[Na+],test
US05284853,CCCCc1nc(=O)c2cc(C=O)ccc2[nH]1.[Li]c1ccccc1>>CCCCc1nc(=O)c2cc(C(O)c3ccccc3)ccc2[nH]1,,C1CCOC1,,,,test
US20080312229A1,COC(=O)Cc1c(C)n(CC(=O)c2ccc(S(C)(=O)=O)cc2)c2ncccc12>>Cc1c(CC(=O)O)c2cccnc2n1CC(=O)c1ccc(S(C)(=O)=O)cc1,,CO,O,[Na+].[OH-],,test
US05270324,CC(C)(OC1CCCCO1)c1ccccc1CC[C@H](O[Si](C)(C)C(C)(C)C)c1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1>>CC(C)(OC1CCCCO1)c1ccccc1CC[C@H](O)c1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110053893A1,CCOP(=O)(/C=C/c1ccc2c(c1)nc(N)c1ncc(CCc3ccc(OC)cc3C)cc12)OCC>>COc1ccc(CCc2cnc3c(N)nc4cc(/C=C/P(=O)(O)O)ccc4c3c2)c(C)c1,,ClCCl,,C[Si](C)(C)Br,,test
US20040186301A1,COC(=O)C(CC(=O)NOC(c1ccccc1)(c1ccccc1)c1ccccc1)CC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)CC(CC(=O)NOC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O,,CO,O,[Na+].[OH-],,test
US20080200697A1,COc1ccc2c(c1)CCC1OC21c1ccccc1>>COc1ccc2c(c1)CCC(=O)C2c1ccccc1,,Cc1ccccc1,,O=S(=O)([O-])[O-].[Mg+2],,test
US04828754,CC[C@H](C)CO.O=C(O)c1ccc(O)cc1Cl>>CC[C@H](C)COC(=O)c1ccc(O)cc1Cl,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,,,test
US20080319005A1,CN1CCC(N(C)c2ccc(N)cc2C(F)(F)F)CC1.O=C(O)Cc1ccc(-n2cnc3ccccc32)cc1>>CN1CCC(N(C)c2ccc(NC(=O)Cc3ccc(-n4cnc5ccccc54)cc3)cc2C(F)(F)F)CC1,,CO,ClCCl,,,test
US20110118354A1,CCOP(=O)(OCC)OC1=C(C(=O)OC)C(C)(c2ccc(Cl)c(Cl)c2)CC(C)C1.[Li]C>>COC(=O)C1=C(C)CC(C)CC1(C)c1ccc(Cl)c(Cl)c1,[Cu]I,CCOCC,,[Cl-].[NH4+],,test
US20020128409A1,CC(=O)c1cccc(C(C)=Nc2c(C)cc(C)cc2C)n1.N[c-]1cccc1.[Fe+2].c1cc[cH-]c1>>CC(=Nc1c(C)cc(C)cc1C)c1cccc(C(C)=N[c-]2cccc2)n1.[Fe+2].c1cc[cH-]c1,,Cc1ccccc1,,,,test
US20070027154A1,CCOC(=O)c1cccc(NC(=O)OCC(Cl)(Cl)Cl)c1.COS(=O)(=O)OC>>CCOC(=O)c1cccc(N(C)C(=O)OCC(Cl)(Cl)Cl)c1,,C1CCOC1,,O,[H-].[Na+],test
US20140171408A1,C[Si](C)(C)Br.Fc1cccc(Cl)c1-c1nc2c(F)cnc(Cl)c2s1>>Fc1cccc(Cl)c1-c1nc2c(F)cnc(Br)c2s1,,CCC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140088101A1,COC(=O)c1ncc2c(cc(-c3ccccc3)c(=O)n2[C@H](C)c2ccccc2)c1O.O=C1CCC(=O)N1Br>>COC(=O)c1nc(Br)c2c(cc(-c3ccccc3)c(=O)n2[C@H](C)c2ccccc2)c1O,,ClCCl,,,,test
US20100256181A1,CN1CCCC1=O.N#C[Cu].O=c1[nH]ccc(C(F)(F)F)c1Oc1cc(Br)cc(Br)c1>>N#Cc1cc(C#N)cc(Oc2c(C(F)(F)F)cc[nH]c2=O)c1,,CCOC(C)=O,,O,,test
US20160168090A1,O=C(NCC1(O)CCCC(F)(F)C1)c1c[nH]c2cccc(Cl)c12.O=C1CCCN1CCO>>O=C(NCC1(O)CCCC(F)(F)C1)c1cn(CCN2CCCC2=O)c2cccc(Cl)c12,,Cc1ccccc1,,CCCCP(=CC#N)(CCCC)CCCC,,test
US20160221972A1,C=O.COC(=O)c1ccc2c(c1)OC[C@H](C(C)C)NC2>>COC(=O)c1ccc2c(c1)OC[C@H](C(C)C)N(C)C2,,CC(=O)O,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20160024016A1,CC1(C)CCC(=O)C[C@H]1O[Si](C)(C)C(C)(C)C.O=S(=O)(N(c1ccc(Cl)cn1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC1(C)CCC(OS(=O)(=O)C(F)(F)F)=C[C@H]1O[Si](C)(C)C(C)(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20120309750A1,C1CCNC1.CCNC(=O)c1noc(-c2cc(C(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)c1-c1noc(C(Cl)(Cl)Cl)n1>>CCNC(=O)c1noc(-c2cc(C(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)c1-c1noc(N2CCCC2)n1,,CN(C)C=O,,,,test
US20070149533A1,CC(C)(C)OC(=O)N1CCc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)cc2C1>>O=C(Nc1cc(Oc2ccc3c(c2)CNCC3)ccn1)C1CC1,,C1COCCO1,Cl,,,test
US06004724,CS(=O)(=O)Cl.N#CC(=C1C=CC(=NO)C=C1)c1ccccc1>>CS(=O)(=O)ON=C1C=CC(=C(C#N)c2ccccc2)C=C1,,C1CCOC1,,CCN(CC)CC,O,test
US20050054883A1,O=C(C(F)(F)F)C(F)(F)C(O)C1CC2C=CC1C2>>OC(C1CC2C=CC1C2)C(F)(F)C(O)C(F)(F)F,,Cc1ccccc1,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20050009906A1,CN(CC[C@@H]1CC[C@@H](CO)CC1)C(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CN(CC[C@@H]1CC[C@@H](COS(C)(=O)=O)CC1)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,Cl,test
US04202899,CCOC(=O)c1cnn2c1nc(Cl)c1cnc3c(cnn3CC)c12.CN1CCNCC1>>CCOC(=O)c1cnn2c1nc(N1CCN(C)CC1)c1cnc3c(cnn3CC)c12,,CCCCO,,,,test
US20160083380A1,CC(=NOCc1ccc(C(F)(F)F)cc1)c1ccc(OCC(=N)NO)cc1.O=C(Cl)Oc1ccccc1>>CC(=NOCc1ccc(C(F)(F)F)cc1)c1ccc(OCC(=NO)NC(=O)Oc2ccccc2)cc1,,ClCCl,,CCN(CC)CC,O,test
US20090023725A1,CCNC(=O)c1cc(F)c(C)c(-c2ccc3c(Br)n[nH]c3c2)c1.Cc1cc(F)ccc1B(O)O>>CCNC(=O)c1cc(F)c(C)c(-c2ccc3c(-c4ccc(F)cc4C)n[nH]c3c2)c1,,CC(C)O,,O=C([O-])O.[Na+],,test
US05061720,CCOC(=O)c1ccc(OCCCN2C(=O)c3ccccc3C2=O)cc1>>CCOC(=O)c1ccc(OCCCN)cc1,,CCO,,NN,O,test
US20140303168A1,CC(C)OC(=O)Cl.Nc1cncc(-c2nnc(NCc3ccccn3)c3c(-c4ccccc4)cccc23)c1>>CC(C)OC(=O)Nc1cncc(-c2nnc(NCc3ccccn3)c3c(-c4ccccc4)cccc23)c1,,ClCCl,,c1ccncc1,,test
US20030166639A1,CC(C)(C)OC(=O)Nc1ccc(C(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-c2ccnc(N3CCCC3)c2)c1>>O=C1CC(c2cccc(-c3ccnc(N4CCCC4)c3)c2)=Nc2ccc(C(F)(F)F)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120029002A1,CC(C)OC(=O)Cl.Nc1nc(-n2nc(Sc3ccccc3F)c3ncccc32)nc(N)c1N>>CC(C)OC(=O)Nc1c(N)nc(-n2nc(Sc3ccccc3F)c3ncccc32)nc1N,,c1ccncc1,,,,test
US20040053941A1,CCO[C@H]1CN(C(=O)OC)C[C@H]1Nc1nc(CC)cnc1CC.O=C1CCC(=O)N1I>>CCO[C@H]1CN(C(=O)OC)C[C@H]1Nc1nc(CC)c(I)nc1CC,,CN(C)C=O,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20070004700A1,CCCCCN.O=C(Cl)OCCl>>CCCCCNC(=O)OCCl,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US05153201,CC(=O)OC(C)=O.COc1cccc(C=Cc2nc3c(s2)NCCC3)c1OC>>COc1cccc(C=Cc2nc3c(s2)N(C(C)=O)CCC3)c1OC,,c1ccncc1,,O=C([O-])O.[Na+],,test
US20100069384A1,CCOc1ccc2c(c1)C(C)(c1ccccc1Cl)C(=O)N2.COc1ccc(S(=O)(=O)Cl)c(OC)c1>>CCOc1ccc2c(c1)C(C)(c1ccccc1Cl)C(=O)N2S(=O)(=O)c1ccc(OC)cc1OC,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US04496558,CC(=O)OC(C)=O.Clc1cccc2c1CCNCC2>>CC(=O)N1CCc2cccc(Cl)c2CC1,,c1ccncc1,,,,test
US04315011,CCC1CCCOC1=O.NCCc1c[nH]c2ccc(Br)cc12>>CCC(CCCO)C(=O)NCCc1c[nH]c2ccc(Br)cc12,,Cc1ccccc1C,,,,test
US20080287437A1,Cc1nc(C(C)N)ccc1F.Clc1ncc(Cl)c(Nc2cc(C3CC3)[nH]n2)n1>>Cc1nc(C(C)Nc2ncc(Cl)c(Nc3cc(C4CC4)[nH]n3)n2)ccc1F,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20150031540A1,COc1cnn(C)c(=O)c1-n1cc(Cl)c2ccccc21>>CN1N=CC(=O)C(n2cc(Cl)c3ccccc32)C1=O,,O,,C1COCCN1,,test
US20070078140A1,Fc1ccc2c(c1)CCN2.O=C(Cl)c1cccnc1Cl>>O=C(c1cccnc1Cl)N1CCc2cc(F)ccc21,,CC#N,,CCN(CC)CC,,test
US20140329807A1,CC(C)(N=[N+]=[N-])[C@@H]1CC[C@@H](Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1>>CC(C)(N)[C@@H]1CC[C@@H](Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1,[Pd],CO,ClCCl,,,test
US05177095,CCCCC(=N)OCC.NNC(=O)c1ccccc1>>CCCCC(=NNC(=O)c1ccccc1)OCC,,CCO,,Cl,,test
US05023256,NC(N)=O.Nc1cccnc1NCc1ccccc1>>Oc1nc2cccnc2n1Cc1ccccc1,,Cc1ccccc1C,,,,test
US20100197651A1,CN(C)C=CC(=O)c1nn(-c2ccc(Cl)cc2)ccc1=O.NNc1ccccc1>>O=c1ccn(-c2ccc(Cl)cc2)nc1-c1ccnn1-c1ccccc1,,CO,,,,test
US20150045368A1,CC1(C)OC(=O)N(c2ccc(-c3cnc(F)c(-c4ncccn4)c3)cc2)[C@H]1c1ccccc1.N>>CC1(C)OC(=O)N(c2ccc(-c3cnc(N)c(-c4ncccn4)c3)cc2)[C@H]1c1ccccc1,,CS(C)=O,,,,test
US20130131039A1,Cn1cc(-c2cc3nccn3c(-c3ccn(C4(CC#N)CN(C(=O)OC(C)(C)C)C4)c3)n2)cn1.O=C(O)C(F)(F)F>>Cn1cc(-c2cc3nccn3c(-c3ccn(C4(CC#N)CNC4)c3)n2)cn1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US05767131,C=CC#N.COc1ccc(C2(c3ccccc3)CCNCC2)cc1>>COc1ccc(C2(c3ccccc3)CCN(CCC#N)CC2)cc1,,CCO,,,,test
US20060235029A1,CCN(CC)CCCNc1nc(-c2ccc(C(=O)O)cc2)c2ccc(=O)n(-c3c(F)cccc3F)c2n1.Nc1ccc(F)cc1>>CCN(CC)CCCNc1nc(-c2ccc(C(=O)Nc3ccc(F)cc3)cc2)c2ccc(=O)n(-c3c(F)cccc3F)c2n1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140249126A1,CCOC(=O)c1cn(CC)c2cc(OC)c(OC)c(F)c2c1=O>>CCn1cc(C(=O)O)c(=O)c2c(F)c(O)c(O)cc21,,CO,ClCCl,BrB(Br)Br,,test
US20150232452A1,CCn1cc(-c2cccc(N)c2)c(-c2ccncc2)n1.O=C=Nc1ccc(Br)cc1F>>CCn1cc(-c2cccc(NC(=O)Nc3ccc(Br)cc3F)c2)c(-c2ccncc2)n1,,ClCCl,,,,test
US20040259923A1,COC(=O)c1nc(NC(C)=O)sc1-c1ccc(SC)cc1>>CSc1ccc(-c2sc(NC(C)=O)nc2C=O)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090042918A1,N#Cc1cccc(Cl)c1N.[N-]=[N+]=[N-]>>Nc1c(Cl)cccc1-c1nnn[nH]1,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US20130237502A1,C1COCCN1.CC(OS(C)(=O)=O)c1ccc(-c2ccc([C@H]3OC(C)(C)N(C(=O)C(F)F)[C@@H]3CF)cc2)cn1>>CC(c1ccc(-c2ccc([C@H]3OC(C)(C)N(C(=O)C(F)F)[C@@H]3CF)cc2)cn1)N1CCOCC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20130225620A1,Cc1c[nH]c2cccc(CN)c12.Clc1nccc(Nc2cc(C3CC3)n[nH]2)n1>>Cc1c[nH]c2cccc(CNc3nccc(Nc4cc(C5CC5)[nH]n4)n3)c12,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US04783396,CCOC(=O)CC(=O)C(C)(C)C.NN>>CC(C)(C)C1CC(=O)NN1,,CCO,,O,O,test
US20090221600A1,CC(C)(C)OC(=O)N1CCC(N)CC1.Cc1ccccc1-c1cc2cnc(S(C)(=O)=O)nc2n([C@H]2CCOC2)c1=O>>Cc1ccccc1-c1cc2cnc(NC3CCN(C(=O)OC(C)(C)C)CC3)nc2n([C@H]2CCOC2)c1=O,,CCOC(C)=O,,,,test
US20150105373A1,CCC(NC(=O)N1CC(=O)N(Cc2ccc(OC)cc2OC)c2nc(C)cnc21)c1ccc(OC(F)(F)F)cc1>>CCC(NC(=O)N1CC(=O)Nc2nc(C)cnc21)c1ccc(OC(F)(F)F)cc1,,O,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20070049581A1,CCOC(=O)CN(C(=O)OC(C)(C)C)C1CCN(C2CCN(Cc3ccccc3)CC2)CC1>>CCOC(=O)CN(C(=O)OC(C)(C)C)C1CCN(C2CCNCC2)CC1,[Pd],CCO,,[H][H],,test
US05994368,CC(=O)[O-].CCOC(=O)c1nc2ccc(CBr)cc2cc1C>>CCOC(=O)c1nc2ccc(COC(C)=O)cc2cc1C,,CN(C)C=O,,O,,test
US05798362,CN(C)C=O.COc1cc2nc(N3CCNCC3)nc(N)c2cc1OC.N=C=NC1CCCCC1.O=C(O)CC(c1ccccc1)c1ccccc1>>O=C(NC1CCCCC1)NC1CCCCC1,CN(C)c1ccncc1,CN(C)C=O,,,,test
US20150076454A1,ClP(Cl)Cl.Oc1cccc(-c2ccccc2)n1>>ClP(Cl)Oc1cccc(-c2ccccc2)n1,,ClCCl,ClCCl,CCN(CC)CC,,test
US20150087639A1,CC(=O)CC(=O)Nc1ccc(NC(C)(C)Cc2ccc3ccccc3c2)c(Cl)c1.N>>C/C(N)=C/C(=O)Nc1ccc(NC(C)(C)Cc2ccc3ccccc3c2)c(Cl)c1,,CO,,,,test
US20020049243A1,N#CCCn1nnnc1[C@@H](N)Cc1ccc(-c2ccccc2)cc1.O=C(O)[C@@H]1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1S(=O)(=O)c1ccc2ccccc2c1>>N#CCCn1nnnc1[C@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)[C@@H]1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1S(=O)(=O)c1ccc2ccccc2c1,,C1CCOC1,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20050277652A1,CC(=O)Cl.Nc1cc(Oc2ccc(NC(=O)CC(=O)Nc3ccc(F)cc3)c(F)c2)ccn1>>CC(=O)Nc1cc(Oc2ccc(NC(=O)CC(=O)Nc3ccc(F)cc3)c(F)c2)ccn1,,CN(C)C=O,,CCN(CC)CC,[Na+].[OH-],test
US20120329785A1,COC(=O)c1scc2c1nc(Cl)c1nn(Cc3ccc(OC)cc3)cc12.COc1ccc(N)cc1OC>>COC(=O)c1scc2c1nc(Nc1ccc(OC)c(OC)c1)c1n[nH]cc12,C1COCCO1,CO,,Cl,,test
US20110263584A1,C=C(OCC)c1cnc(Cl)nc1>>CC(=O)c1cnc(Cl)nc1,,C1CCOC1,,Cl,,test
US20090281317A1,COC(=O)CCN1CCN(C(=S)NN=C(C)c2csc(-c3ccc(Br)cc3)c2O)CC1>>CC(=NNC(=S)N1CCN(CCC(=O)O)CC1)c1csc(-c2ccc(Br)cc2)c1O,,CCO,,,,test
US20040063904A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNC(=O)[C@@H](N)C(C)(C)c1ccccc1>>CN(C(=O)OC(C)(C)C)C(=O)[C@@H](N)C(C)(C)c1ccccc1,,CC#N,,,,test
US20100137281A1,CCc1cc2c(=O)n(CC(=O)c3ccc(OC)cc3)c(=O)n(Cc3ccc(-c4ccccc4-c4noc(=O)[nH]4)cc3)c2s1.NOCC(=O)O>>CCc1cc2c(=O)n(CC(=NOCC(=O)O)c3ccc(OC)cc3)c(=O)n(Cc3ccc(-c4ccccc4-c4noc(=O)[nH]4)cc3)c2s1,,ClC(Cl)Cl,O,Cl,c1ccncc1,test
US20050209241A1,CNS(=O)(=O)c1ccc(OC(C)C(F)(F)F)c(C(=O)OC)c1>>CNS(=O)(=O)c1ccc(OC(C)C(F)(F)F)c(C(=O)O)c1,,C1CCOC1,,[Na+].[OH-],,test
US20150018363A1,CC(=O)c1nc2ccc(Br)cc2n1C.O=c1cc(OCc2ccc(Cl)cc2)cc[nH]1>>CC(=O)c1nc2ccc(-n3ccc(OCc4ccc(Cl)cc4)cc3=O)cc2n1C,I[Cu]I,CS(C)=O,,CNCCNC,O=C([O-])[O-].[K+].[K+],test
US20100252433A1,CCOC(=O)/C=C/c1cc(/C=C/C(=O)N(C)C)c[nH]1>>CCOC(=O)CCc1cc(CCC(=O)N(C)C)c[nH]1,[Pd],CCO,,,,test
US20130303559A1,COC(=O)OC(=O)OC.Nc1nc(-n2nc(Sc3ccccc3F)c3ccccc32)nc(N)c1N>>COC(=O)Nc1c(N)nc(-n2nc(Sc3ccccc3F)c3ccccc32)nc1N,,CC(C)O,,CN1CCCC1=O,,test
US20090137588A1,CN(c1ccccc1)c1cc(Nc2cccc(NC(=O)OC(C)(C)C)c2)ncn1>>CN(c1ccccc1)c1cc(Nc2cccc(N)c2)ncn1,,O=C(O)C(F)(F)F,,,,test
US05474994,Cc1ccccc1N1CCN(CC(=O)c2cccc3c(=O)c(C)c(-c4ccccc4)oc23)CC1.Cl>>Cc1ccccc1N1CCN(CC(O)c2cccc3c(=O)c(C)c(-c4ccccc4)oc23)CC1.Cl,,CCO,,,,test
US20030092712A1,COc1cc(-c2ccc(F)cc2Cl)c2cnc(=O)n(-c3c(Cl)cccc3Cl)c2c1.C[Mg]Br>>COc1cc(-c2ccc(F)cc2Cl)c2c(c1)N(c1c(Cl)cccc1Cl)C(=O)N(C)C2,,C1CCOC1,,,,test
US20050107616A1,CC(C)(C)C=O.Clc1cc(-c2nnco2)cc(Cl)n1>>CC(C)(C)[C@H](O)c1nnc(-c2cc(Cl)nc(Cl)c2)o1,,C1CCOC1,,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US06596730B1,COC(=O)c1cc(N)ccc1OC.Cc1cc(N)c2ncccc2n1.O=C(n1ccnc1)n1ccnc1>>COC(=O)c1cc(NC(=O)Nc2cc(C)nc3cccnc23)ccc1OC,,CCOC(C)=O,CN(C)C=O,,,test
US05290789,CC(C)=CCC1(C)C(C)CCN(Cc2ccccc2)C1C.O=[O+][O-]>>CC1CCN(Cc2ccccc2)C(C)C1(C)CCO,,CCO,,Cl,[BH4-].[Na+],test
US20030087926A1,CCOC(=O)C1Nc2cc(Cl)cc(Cl)c2C2C=CCC12>>O=C(O)C1Nc2cc(Cl)cc(Cl)c2C2C=CCC12,,CCO,,[Na+].[OH-],,test
US20160137637A1,Nc1nc2cc(C(=O)N3CCOCC3)ccc2[nH]1.O=C(O)c1csc(-c2ccc3c(c2)CCO3)n1>>O=C(Nc1nc2cc(C(=O)N3CCOCC3)ccc2[nH]1)c1csc(-c2ccc3c(c2)CCO3)n1,CN(C)c1ccncc1,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090069336A1,CC(Br)C(=O)c1cc2c(-c3ccc(Cl)cc3Cl)nc(N)nc2s1.NC(N)=S>>Cc1sc(N)nc1-c1cc2c(-c3ccc(Cl)cc3Cl)nc(N)nc2s1,,CCO,,,,test
US20160176861A1,COC(=O)c1[nH]c(=O)oc1C1CC1.CS(=O)(=O)OCCc1c(Cl)cccc1Cl>>COC(=O)c1c(C2CC2)oc(=O)n1CCc1c(Cl)cccc1Cl,,CN(C)C=O,O,[H-].[Na+],,test
US04339267,Cc1nc(N)nc2c1CCC2.O=C=NS(=O)(=O)c1ccccc1[N+](=O)[O-]>>Cc1nc(NC(=O)NS(=O)(=O)c2ccccc2[N+](=O)[O-])nc2c1CCC2,,ClCCl,,,,test
US20130085148A1,CC(O)c1cc(-c2ccc(F)cc2)no1>>CC(=O)c1cc(-c2ccc(F)cc2)no1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20110152321A1,C#CCCCNC(=O)[C@H](CC)NC(=O)C(F)(F)F.Nc1ccccc1I>>CC[C@H](NC(=O)C(F)(F)F)C(=O)NCCCC#Cc1ccccc1N,I[Cu]I,,,CCNCC,,test
US08629133B2,C[Si](C)(C)CCOC(=O)N[C@@H]1CC[C@@H](/C(N)=N/O)CC1.O=C(n1ccnc1)n1ccnc1>>C[Si](C)(C)CCOC(=O)N[C@@H]1CC[C@@H](c2noc(=O)[nH]2)CC1,,ClCCl,,C1CCOC1,,test
US20010027196A1,COC(=O)CCl.N#Cc1c(-c2ccccc2)nc(N)[nH]c1=S>>COC(=O)CSc1nc(N)nc(-c2ccccc2)c1C#N,,CO,,C[O-].[Na+],,test
US20080021032A1,CC(C)(O)Cn1ccc(N)n1.O=C(O)[C@H](CC1CCCC1)c1ccc(S(=O)(=O)C2CC2)cc1>>CC(C)(O)Cn1ccc(NC(=O)[C@H](CC2CCCC2)c2ccc(S(=O)(=O)C3CC3)cc2)n1,CN(C)C=O,ClCCl,,Cc1cccc(C)n1,O=C(Cl)C(=O)Cl,test
US05254685,CN1CCc2c(CC(=O)O)c(F)cc3c(=O)c(C(=O)O)cn1c23>>Cc1c(F)cc2c(=O)c(C(=O)O)cn3c2c1CCN3C,,CCO,,CCN(CC)CC,,test
US20150111734A1,CCN(C(=O)CC1CCN([Si](C)(C)C(C)(C)C)C1=O)c1cn(-c2cccnc2)nc1Cl>>CCN(C(=O)CC1CCNC1=O)c1cn(-c2cccnc2)nc1Cl,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080261952A1,Nc1ccc(N2CCCC2)c(F)c1.O=C=Nc1ccc(Cl)cc1>>O=C(Nc1ccc(Cl)cc1)Nc1ccc(N2CCCC2)c(F)c1,,ClCCl,,,,test
US20020173646A1,COC(CBr)OC.COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1O>>COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCC(OC)OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070021484A1,C/C(=C\c1ccc(F)cc1F)CN.Cn1ccnc1C=O>>CC(=Cc1ccc(F)cc1F)CNCc1nccn1C,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20120122846A1,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.[N-]=[N+]=NC1CCCN(C(=O)OCc2ccccc2)CC1O>>CC(C)(C)[Si](C)(C)OC1CN(C(=O)OCc2ccccc2)CCCC1N=[N+]=[N-],,ClCCl,,,,test
US05981533,Cl.Nc1cccc(Cl)c1>>Cl.Nc1cccc(Cl)c1,,CO,Cl,,,test
US04250099,CC(=O)/C=C/C1C(C)=CCCC1(C)C.CI>>CC(=O)/C=C/C1C(C)=CCC(C)C1(C)C,,CCOCC,,[Mg],[Cl-].[NH4+],test
US20030162818A1,CCCCCCCCCC(=O)Cl.COc1ccc(COc2cccc(C(=O)Nc3ccccc3S(N)(=O)=O)c2)cc1>>CCCCCCCCCC(=O)NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCc2ccc(OC)cc2)c1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20070212569A1,COc1ccc(Br)c2ccccc12.OB(O)c1ccc2ccccc2c1>>COc1ccc(-c2ccc3ccccc3c2)c2ccccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O,O=C([O-])[O-].[K+].[K+],test
US20090270460A1,CI.COC(=O)c1c(C)[nH]c2cc(Cl)ccc12>>COC(=O)c1c(C)n(C)c2cc(Cl)ccc12,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20110224188A1,CC(C)(C)OC(=O)NC1(c2ccc(I)cn2)CC1.NC(=O)C1CC1>>CC(C)(C)OC(=O)NC1(c2ccc(NC(=O)C3CC3)cn2)CC1,[Cu]I,C1COCCO1,CCOC(C)=O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20120302641A1,CC(Nc1ccc(-c2ccc(Cl)cc2)cc1)c1ccc(Cl)cc1Br.CCOC(=O)c1ccc(B(O)O)cc1>>CCOC(=O)c1ccc(-c2cc(Cl)ccc2C(C)Nc2ccc(-c3ccc(Cl)cc3)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100286185A1,Cc1ccccc1.Oc1cc2ccccc2nc1Cl>>C=Cc1nc2ccccc2cc1O,,CS(C)=O,,,,test
US20150011773A1,CC(C)(C)OC(=O)N[C@@H](C[C@H](Cc1ccc(N)cc1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)OCCCOS(=O)(=O)c2ccc(C)cc2)cc1>>Cc1ccc(S(=O)(=O)OCCCNc2ccc(C[C@@H](C[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150218116A1,C1CCNC1.CS(=O)(=O)OCCS(=O)(=O)Cc1ccc(Br)cc1>>O=S(=O)(CCN1CCCC1)Cc1ccc(Br)cc1,,ClCCl,,,,test
US20100096252A1,CCOC(=O)COc1cccc2[nH]ccc12>>CCOC(=O)COc1cccc2c1CCN2,,CC(=O)O,,[BH3-]C#N.[Na+],,test
US20030139390A1,O=C(OO)c1cccc(Cl)c1.O=S(=O)(Nc1ccc(Sc2ccc3ccccc3c2)c(Cl)c1)c1ccc(Cl)nc1>>O=S(c1ccc2ccccc2c1)c1ccc(NS(=O)(=O)c2ccc(Cl)nc2)cc1Cl,,CCOC(C)=O,ClCCl,,,test
US20160272617A1,Cc1cc(C(=O)NC2CCC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)O)cc1.Nc1cc(Cl)c2oc(=O)[nH]c2c1>>Cc1cc(C(=O)NC2CCC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2cc(Cl)c3oc(=O)[nH]c3c2)cc1,,CCOC(C)=O,CS(C)=O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US05439928,Brc1ccccc1.C1CCOC1.CCOC(=O)CCCc1cncn1Cc1ccccc1>>OC(CCCc1cncn1Cc1ccccc1)(c1ccccc1)c1ccccc1,,C1CCOC1,,[Mg],[Cl-].[NH4+],test
US20100069431A1,COC(=O)c1cc(OCc2ccccc2)ccc1N.O=S(=O)(Cl)c1cccs1>>COC(=O)c1cc(OCc2ccccc2)ccc1NS(=O)(=O)c1cccs1,,ClCCl,,c1ccncc1,,test
US20070010529A1,CC(C)(C)OC(=O)N1CCNCC1.Cc1cc(CBr)ccc1[N+](=O)[O-]>>Cc1cc(CN2CCN(C(=O)OC(C)(C)C)CC2)ccc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040082570A1,CC#CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2[nH]c(=O)n(COC(=O)C(C)(C)C)c(=O)c21.CCOCCBr>>CC#CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2c1c(=O)n(COC(=O)C(C)(C)C)c(=O)n2CCOCC,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20050137193A1,Nc1ccc(Cl)cc1C(=O)c1cccnc1.O=S(=O)(Cl)c1ccc(Br)c(F)c1>>O=C(c1cccnc1)c1cc(Cl)ccc1NS(=O)(=O)c1ccc(Br)c(F)c1,,c1ccncc1,,,,test
US20040138277A1,CCOC(=O)C(C)(Cc1ccc(O)cc1)Oc1ccc(C2CCCCC2)cc1.Cc1ccc(S(=O)(=O)OCCc2nc(-c3ccc(-c4ccccc4)cc3)oc2C)cc1>>Cc1oc(-c2ccc(-c3ccccc3)cc2)nc1CCOc1ccc(CC(C)(Oc2ccc(C3CCCCC3)cc2)C(=O)O)cc1,,CCO,,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US05075043,CCCCOC(=O)CCCCCBr.CNc1ccccc1>>CCCCOC(=O)CCCCCN(C)c1ccccc1,,CCCCO,,[I-].[K+],,test
US20160016948A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OC1CCNCC1C(F)(F)F>>CC(C)(C)OC(=O)N1CCC(O)C(C(F)(F)F)C1,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US05712274,CCOC(=O)C1(CC(=O)O)N=C(c2ccc(Cl)cc2)c2c(sc(C)c2C)-n2c(C)nnc21>>Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(CC(=O)O)c1nnc(C)n1-2,,CCO,,[Na+].[OH-],,test
US20120301401A1,O=C(O)CBr.OCCOC1CCCCO1>>O=C(O)COCCOC1CCCCO1,,C1CCOC1,,CN(C)C=O,[H-].[Na+],test
US20100305133A1,CC1(C)OB(c2cn(S(=O)(=O)c3ccccc3)c3ccccc23)OC1(C)C.CCOC(=O)CNC(=O)c1c(O)c(Br)cc2nccnc12>>CCOC(=O)CNC(=O)c1c(O)c(-c2cn(S(=O)(=O)c3ccccc3)c3ccccc23)cc2nccnc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US04833164,BrBr.Oc1c(Cc2ccccc2)ccc2ccccc12>>Oc1c(Cc2ccccc2)cc(Br)c2ccccc12,,CC(=O)O,,O,,test
US20140088153A1,COC(=O)c1cc(NC(=O)c2c(C(F)(F)F)c(C(F)(F)C(F)(F)F)nn2C)ccc1Cl>>Cn1nc(C(F)(F)C(F)(F)F)c(C(F)(F)F)c1C(=O)Nc1ccc(Cl)c(C(=O)O)c1,,CO,,Cl,[Na+].[OH-],test
US20120010183A1,C[C@@H](Oc1ncc(O)cc1Cl)C(F)(F)F.Cc1ccc(OC(=O)c2cc(Cl)c(F)cc2F)cc1>>Cc1ccc(OC(=O)c2cc(Cl)c(Oc3cnc(O[C@H](C)C(F)(F)F)c(Cl)c3)cc2F)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050130960A1,CC(Cn1ncc2ccc(O)cc21)NC(=O)OCc1ccccc1.O=C1CCC(=O)N1Br>>CC(Cn1ncc2ccc(O)c(Br)c21)NC(=O)OCc1ccccc1,,C1CCOC1,ClCCl,[Cl-].[NH4+],,test
US20100093724A1,CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(C=O)c1.[Li]C>>CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(C(C)O)c1,,C1CCOC1,CCOCC,,,test
US05707989,O=S(Cl)Cl.Oc1ncnc2cnc(NC3CC3)nc12>>Clc1ncnc2cnc(NC3CC3)nc12,CN(C)C=O,,,,,test
US20140051656A1,COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(Br)cc2)[nH]1)C(C)C.C[Si](C)(C)CCOCCl>>COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(Br)cc2)n1COCC[Si](C)(C)C)C(C)C,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20130005730A1,COCCCOc1cc(C[C@@H](C[C@H](N)[C@@H](O)C[C@H](C(=O)NCC(C)(C)C(N)=O)C(C)C)C(C)C)ccc1OC.ClCCl.O=C(Cl)OCCl>>COCCCOc1cc(C[C@@H](C[C@H]2[C@H](C[C@H](C(=O)NCC(C)(C)C(N)=O)C(C)C)OCN2C(=O)OCCl)C(C)C)ccc1OC,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20100144884A1,CCCCO.O=Cc1ccc(O)c(Br)c1>>CCCCOc1cc(C=O)ccc1O,Cl[Cu],CCCCO,,Cl,,test
US20120149723A1,CN(C)C=O.CN[C@@H]1CCCC[C@H]1NC.O=C([O-])[O-].c1c[nH]nn1>>COC(=O)c1nc(C)ccc1-n1nccn1,[Cu]I,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070129346A1,CCOC(=O)C(C)(C)CO.CI>>CCOC(=O)C(C)(C)COC,,CC#N,,,,test
US20150238601A1,CCOC(COc1cccc(-c2nccc(Nc3ccc4c(cnn4C(=O)OC(C)(C)C)c3)n2)c1)OCC>>O=CCOc1cccc(-c2nccc(Nc3ccc4[nH]ncc4c3)n2)c1,,C1CCOC1,,Cl,,test
US20130115190A1,BrC1CC1.Oc1cnc(Cl)c2ccccc12>>Clc1ncc(OC2CC2)c2ccccc12,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040014766A1,CNc1ccc(Cc2nc3c([nH]2)c(=O)n(Cc2ccccc2F)c(=O)n3CC2CC2)cc1.COc1ccc(C(=O)O)c(OC)n1>>COc1ccc(C(=O)N(C)c2ccc(Cc3nc4c([nH]3)c(=O)n(Cc3ccccc3F)c(=O)n4CC3CC3)cc2)c(OC)n1,CN(C)c1ccncc1,CCN(CC)CC,,,,test
US20090163524A1,CC(C)(C)OC(=O)NC1(C(=O)O)CCN(c2ncnc3[nH]ccc23)CC1.N[C@@H](CCO)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)NC1(C(=O)N[C@@H](CCO)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150266881A1,CC(C)(C)OC(=O)N(CC1CC1)[C@@H]1C[C@H]1c1ccc(F)c(C(=O)NC2CC(F)(F)C2)c1.Cl>>Cl.O=C(NC1CC(F)(F)C1)c1cc([C@@H]2C[C@H]2NCC2CC2)ccc1F,,CO,,,,test
US05294714,CC(=O)N1C(=O)C(=Cc2ccccc2)NC(=O)C1CC#N>>N#CCC1NC(=O)C(=Cc2ccccc2)NC1=O,,CN(C)C=O,,NN,O,test
US20060211680A1,C(=NC1CCCCC1)=NC1CCCCC1.CN(C)C=O.Cc1cc(O)c(C(=O)C=Cc2cccc(OCC(=O)O)c2)c(=O)n1C.O=C1CCC(=O)N1O>>Cc1cc(O)c(C(=O)C=Cc2cccc(OCC(=O)OCCCCCCCCCO)c2)c(=O)n1C,,CN(C)C=O,,,,test
US04579854,CC(=O)c1ccc(O)c2[nH]c(=O)ccc12.ClCc1ccccc1>>CC(=O)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12,,O,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20060223849A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C1=NCCc2cc(OC)c(OC)cc21>>CCOC(=O)C1c2cc(OC)c(OC)cc2CCN1C(=O)OC(C)(C)C,[Pd],CCO,ClCCl,CCN(CC)CC,,test
US05347013,CCCN(CCC)[C@H]1Cc2c(C(C)=O)ccc3c2[C@@H](CN3)C1.CCN(CC)CC.O=C(Cl)OCC(Cl)(Cl)Cl>>NC(=O)N1CCc2ccccc21,,ClCCl,,,,test
US20120010241A1,Cc1nn(-c2ccc(C#N)cc2)c2cccc(-c3cnc4ccccc4c3)c12.OO>>Cc1nn(-c2ccc(C(N)=O)cc2)c2cccc(-c3cnc4ccccc4c3)c12,,CS(C)=O,O,CCO,[Na+].[OH-],test
US20150021575A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(O)OC1(C)C,,CS(C)=O,,O,CC(=O)[O-].[K+],test
US20150225422A1,CI.O=C(Nc1cncc(Br)c1)c1ccc(F)cc1F>>CN(C(=O)c1ccc(F)cc1F)c1cncc(Br)c1,,CN(C)C=O,,[H-].[Na+],,test
US20110059043A1,COC(=O)c1cc(Cl)ccc1O.COCCBr>>COCCOc1ccc(Cl)cc1C(=O)OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150133457A1,C=CC(=O)Cl.Nc1cccc(Oc2nc(Cl)ncc2F)c1>>C=CC(=O)Nc1cccc(Oc2nc(Cl)ncc2F)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20130236468A1,CC(C)(O)CN.O=C(O)C1CCN(Cc2ccc([C@H]3COc4cccnc4O3)cc2)CC1>>CC(C)(O)CNC(=O)C1CCN(Cc2ccc([C@H]3COc4cccnc4O3)cc2)CC1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04468392,O=C1NCCCCC1Br.Sc1ccc(Cl)cc1>>O=C1NCCCCC1Sc1ccc(Cl)cc1,,CO,,C[O-].[Na+],,test
US20080139856A1,CC(=O)CC=C=C(C)CCCC(C)CCCC(C)C>>CC(=O)CCCC(C)CCCC(C)CCCC(C)C,[Pd],,,,,test
US20090286807A1,Cc1ccc(F)cc1N1CC(C)(C)N(C[C@H](N)[C@@H](O)C[C@H](C(=O)NCC(C)(C)C)C(C)C)CC1=O.Cc1ccc(F)cc1N1CC(C)(C)N(C[C@H](NC(=O)OC(C)(C)C)[C@@H](O)C[C@H](C(=O)NCC(C)(C)C)C(C)C)CC1=O.O=C(O)/C=C/C(=O)O>>Cc1ccc(F)cc1N1CC(C)(C)N(C[C@H](N)[C@@H](O)C[C@H](C(=O)NCC(C)(C)C)C(C)C)CC1=O.Cc1ccc(F)cc1N1CC(C)(C)N(C[C@H](N)[C@@H](O)C[C@H](C(=O)NCC(C)(C)C)C(C)C)CC1=O.O=C(O)/C=C/C(=O)O,,CO,ClCCl,O=C(O)C(F)(F)F,,test
US06211242B1,COc1ccc(N(C(=O)c2ccc(N)cc2)C2CCCC2)cc1.Cc1ccccc1C(=O)Cl>>COc1ccc(N(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)C2CCCC2)cc1,,ClCCl,,c1ccncc1,,test
US20080182852A1,CC(C)NC(=O)c1ccccc1Nc1nc(Cl)ncc1F.C[C@@H]1CN(c2cccc(N)c2)C(=O)CN1C(=O)C(F)(F)F>>CC(C)NC(=O)c1ccccc1Nc1nc(Nc2cccc(N3C[C@@H](C)NCC3=O)c2)ncc1F,Cl,,,,,test
US20120101083A1,CC(C)Nc1ccc(-c2nc(-c3ccc4c(c3)CCN(C(=O)CNC(=O)OC(C)(C)C)CC4)no2)cc1C#N>>CC(C)Nc1ccc(-c2nc(-c3ccc4c(c3)CCN(C(=O)CN)CC4)no2)cc1C#N,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110166141A1,CCOC(=O)CNC(=O)C(=O)[C@@H](COCc1ccccc1)NC(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc(C(=O)OC)c(NC(=O)OC(C)(C)C)c1>>CCOC(=O)CNC(=O)C(=O)C(COCc1ccccc1)NC(=O)[C@@H](CC1CCCCC1)NC(=O)c1ccc(C(=O)OC)c(N)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030069297A1,COc1ccc(-c2cccc3c2CC(=O)N3)cc1.Cc1cc(C(=O)N2CC[C@@H](N(C)C)C2)c(C=O)[nH]1>>COc1ccc(-c2cccc3c2C(=Cc2[nH]c(C)cc2C(=O)N2CC[C@@H](N(C)C)C2)C(=O)N3)cc1,C1CCNCC1,CCO,,,,test
US05663164,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.c1ccc(-c2cccs2)nc1>>O=S(=O)([O-])C(F)(F)F.c1c[nH+]c2sccc2c1,,ClCCl,,,,test
US04568687,NCCCn1cnc(-c2ccccc2)c1.O=C(Cl)c1ccc(Br)cc1>>O=C(NCCCn1cnc(-c2ccccc2)c1)c1ccc(Br)cc1,,ClCCl,,[Na+].[OH-],,test
US20130196974A1,Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(N3C[C@H](N)[C@H](O)C3)c2c1.N#CBr>>Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(N3C[C@H]4N=C(N)O[C@H]4C3)c2c1,,CO,,CC(=O)[O-].[Na+],,test
US20150005357A1,COC(=O)c1c(SC)cc(-c2ccc3ccc4cccc5ccc2c3c45)oc1=O.O=C1CCCc2nn(-c3ccccc3)cc21>>COC(=O)c1c(SC)cc(-c2ccc3ccc4cccc5ccc2c3c45)c2c1-c1cn(-c3ccccc3)nc1CC2,,CN(C)C=O,,Cl,[K+].[OH-],test
US05128356,CCOC(=O)c1cccc2nc(CO)n(Cc3ccc(-c4ccccc4-c4nnn[nH]4)cc3)c12.O=S(Cl)Cl>>CCOC(=O)c1cccc2nc(CCl)n(Cc3ccc(-c4ccccc4-c4nnn[nH]4)cc3)c12,,ClCCl,,,,test
US20100311734A1,O=C(O)Cc1ccccc1Cc1ccccc1>>O=C1Cc2ccccc2Cc2ccccc21,,O,,,,test
US20100286116A1,CC(N)CO.Cc1nc(CCc2c(-c3ccccc3)noc2C)sc1C(=O)O>>Cc1nc(CCc2c(-c3ccccc3)noc2C)sc1C(=O)NC(C)CO,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US03933853,CC(=O)Cc1cn(Cc2ccccc2Cl)c2ccccc12.NO>>CC(Cc1cn(Cc2ccccc2Cl)c2ccccc12)=NO,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US03991076,CCNCCN.O=C(CC1CSCCC1=O)c1ccc(Br)cc1>>CCNCCn1c(-c2ccc(Br)cc2)cc2c1CCSC2,Cl,O,,CCO,,test
US06200981B1,CCOC(=O)CN(c1cc(CO)cc(C(=O)OC)c1)C(c1ccccc1)c1ccccc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCOC(=O)CN(c1cc(CCl)cc(C(=O)OC)c1)C(c1ccccc1)c1ccccc1,,C1CCOC1,,c1ccncc1,,test
US20090221608A1,C=C(C)B1OC(C)(C)C(C)(C)O1.Nc1ncc(Br)cc1I>>C=C(C)c1cc(Br)cnc1N,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],test
US04715994,C=C(CBr)C(=O)OC.CC(NC(=O)OCc1ccccc1)P(O)O>>C=C(CP(=O)(O)C(C)NC(=O)OCc1ccccc1)C(=O)OC,,ClCCl,,CCN(CC)CC,C[Si](C)(C)Cl,test
US20100204196A1,COc1cc2c(cc1[N+](=O)[O-])N(C(=O)[C@@H](C)N(C)C)CC2>>COc1cc2c(cc1N)N(C(=O)[C@@H](C)N(C)C)CC2,[Pd],CCOC(C)=O,,,,test
US06320068B1,COC(=O)c1c(O)ccc2ccccc12.O=S(=O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>COC(=O)c1c(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)ccc2ccccc12,,C1CCOC1,,CCN(CC)CC,Cc1ccccc1,test
US03992375,NN.O=C(O)N1Cc2ccccc2Oc2ccc(Cl)cc21.O=C1C=CC(=O)O1>>O=C(O)C=CC(=O)NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21,,ClCCl,c1ccccc1,,,test
US20120149662A1,CC(C)(C)OC(=O)N1CC(CC#N)(n2cc(-c3cnnc4c3ccn4COC(=O)C(C)(C)C)cn2)C1>>CC(C)(C)OC(=O)N1CC(CC#N)(n2cc(-c3cnnc4[nH]ccc34)cn2)C1,,CO,,[Na+].[OH-],,test
US20140094473A1,CCOC(=O)CC(N)C1(C)CCCC1.N#Cc1cc(F)c(Cl)nc1Cl>>CCOC(=O)C[C@@H](Nc1nc(Cl)c(C#N)cc1F)C1(C)CCCC1,,C1CCOC1,,CCN(CC)CC,,test
US20100041663A1,Cc1c(Cc2ccccc2)nnc(N2CCN(c3cnc(C(=O)CO)cn3)[C@H](C)C2)c1C>>Cc1c(Cc2ccccc2)nnc(N2CCN(c3cnc(C(O)CO)cn3)[C@H](C)C2)c1C,,CCO,,Cl,[BH4-].[Na+],test
US20060257987A1,CCc1ccc(O)c(Br)c1.OB(O)c1cccnc1>>CCc1ccc(O)c(-c2cccnc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20050187298A1,CNc1cccc(Br)c1.O=CO>>CN(C=O)c1cccc(Br)c1,,O,,,,test
US20050245529A1,CCCNCC1CC1.ClC/C=C/c1ccc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)cc1>>CCC(C/C=C/c1ccc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)cc1)N(C)C1CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20050288290A1,COc1cn2ncnc(Oc3ccc(NC(=S)NC(=O)Cc4ccc(F)cc4)cc3F)c2c1C.Cc1c(OCCN2CCOCC2)cn2ncnc(Oc3ccc(NC(=O)CC(=O)Nc4ccc(F)cc4)cc3F)c12.Cl>>Cc1c(OCCN2CCOCC2)cn2ncnc(Oc3ccc(NC(=S)NC(=O)Cc4ccc(F)cc4)cc3F)c12.Cl,,C1CCOC1,,,,test
US20120149707A1,COc1cc(C)c(C=O)cc1C.C[Mg]Br>>COc1cc(C)c(C(C)O)cc1C,,C1CCOC1,O,Cl,,test
US20060287300A1,BrCc1ccccc1.COC1=CC(=O)C(O)(CCC(C)C)c2ccccc21>>COC1=CC(=O)C(CCC(C)C)(OCc2ccccc2)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20080167318A1,CON=C1CN[C@H](c2nc3ccccc3[nH]2)C1.O=C(Cl)c1ccc(-c2ccccc2)cc1>>CO/N=C1/C[C@@H](c2nc3ccccc3[nH]2)N(C(=O)c2ccc(-c3ccccc3)cc2)C1,,ClCCl,,CCN(CC)CC,,test
US20120316195A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=C1OCc2cc(Br)ccc21>>CC1(C)OB(c2ccc3c(c2)COC3=O)OC1(C)C,,C1COCCO1,CCOC(C)=O,ClCCl,CC(=O)[O-].[K+],test
US20110301122A1,CC(C)[Si](Cl)(C(C)C)C(C)C.CCOC(=O)c1cccc(O)c1>>CCOC(=O)c1cccc(O[Si](C(C)C)(C(C)C)C(C)C)c1,,CN(C)C=O,,O,c1c[nH]cn1,test
US20100261771A1,CCOC(=O)CCl.COCCn1c(-c2ccc(Cl)s2)n[nH]c1=O>>CCOC(=O)Cn1nc(-c2ccc(Cl)s2)n(CCOC)c1=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080207654A1,CCSc1nc(C)cc(=O)[nH]1.N#Cc1ccccc1-c1ccc(CBr)cc1>>CCSc1nc(C)cc(=O)n1Cc1ccc(-c2ccccc2C#N)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130338140A1,O=C(C[C@H](C[N+](=O)[O-])c1ccc(Cl)c(F)c1)N1C(=O)OC[C@@H]1Cc1ccccc1>>O=C1C[C@@H](c2ccc(Cl)c(F)c2)CN1,[Ni],CCO,CCOC(C)=O,,,test
US20090163524A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C1(CN)CCN(c2ncnc3[nH]ccc23)CC1>>CCOC(=O)C1(CNC(=O)OC(C)(C)C)CCN(c2ncnc3[nH]ccc23)CC1,,ClCCl,,CCN(CC)CC,,test
US20100094000A1,CC(C)(C)OC(=O)NN.O=Cc1cccnc1>>CC(C)(C)OC(=O)NN=Cc1cccnc1,,CCO,,,,test
US20070179148A1,CC(C)N=C=O.CC(C)[C@@H](N)C(=O)N1CCN(c2ccc(Cl)cc2)C(C)(C)C1>>CC(C)NC(=O)N[C@@H](C(=O)N1CCN(c2ccc(Cl)cc2)C(C)(C)C1)C(C)C,,ClCCl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20130029962A1,N#Cc1ncc([N+](=O)[O-])cc1F>>N#Cc1ncc(N)cc1F,[Fe],CC(=O)O,CCOC(C)=O,,,test
US20150018343A1,CCOC(=O)C(F)(F)Oc1ccccc1C(=O)N1Cc2nn3c(C)c(Cl)c(C)nc3c2C1>>Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccccc1OC(F)(F)CO)C3,,C1COCCO1,CCOC(C)=O,[BH4-].[Li+],,test
US05763437,CC(=O)c1sccc1CN1C(=O)C(NC(=O)OC(C)(C)C)N=C(C2CCCCC2)c2ccccc21>>CC(=O)c1sccc1CN1C(=O)C(N)N=C(C2CCCCC2)c2ccccc21,,CCOC(C)=O,,Cl,,test
US20120122840A1,C1COCCN1.C=Cc1nc(Cl)nc2c1ncn2C1CCCCO1>>Clc1nc(CCN2CCOCC2)c2ncn(C3CCCCO3)c2n1,,ClCCl,,,,test
US20060189663A1,O=C(Cl)C(=O)Cl.O=C1NC(=O)C(c2ccccc2)=C1O>>O=C1NC(=O)C(c2ccccc2)=C1Cl,,ClCCl,,CN(C)C=O,,test
US20070203129A1,Cc1c(C(=O)C(C)Br)cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n1-c1cccc(C(F)(F)F)c1.NC(N)=S>>Cc1sc(N)nc1-c1cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n(-c2cccc(C(F)(F)F)c2)c1C,,CCO,,CC(=O)[O-].[Na+],,test
US04415572,ClCc1ccc(Cl)cc1.O=C1CCc2cc(N3CCNCC3)ccc2N1>>O=C1CCc2cc(N3CCN(Cc4ccc(Cl)cc4)CC3)ccc2N1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130143925A1,CCC(=O)N1CCC(NC(=O)Nc2ccc(C(=O)OC)cc2)CC1>>CCC(=O)N1CCC(NC(=O)Nc2ccc(C(=O)O)cc2)CC1,,CCO,,[Na+].[OH-],,test
US20140221345A1,CCOC(=O)COc1cccc2c1N(C)C(=O)CO2.NCC(O)CN1CCc2ccccc2C1>>CN1C(=O)COc2cccc(OCC(=O)NCC(O)CN3CCc4ccccc4C3)c21,,CCO,,,,test
US20060019997A1,CC(O)c1cnn(-c2cccc(Cl)c2)n1.O=S(Cl)Cl>>CC(Cl)c1cnn(-c2cccc(Cl)c2)n1,CN(C)C=O,,,,,test
US20090274655A1,COC(=O)c1sc(-c2ccc(N)cc2)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C(C)C.O=C(O)c1cocn1>>COC(=O)c1sc(-c2ccc(NC(=O)c3cocn3)cc2)cc1N(C(=O)[C@@H]1CC[C@@H](C)CC1)C(C)C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040152690A1,BrCc1ccccc1.FC(F)(F)c1ccc2nc(N3CCN(c4ncccc4C(F)(F)F)CC3)[nH]c2c1>>FC(F)(F)c1ccc2c(c1)nc(N1CCN(c3ncccc3C(F)(F)F)CC1)n2Cc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20070066615A1,Nc1ccc(N2CCNC2=O)cc1.O=C(NC[C@H]1CO1)c1ccc(Cl)s1>>O=C(NC[C@H](O)CNc1ccc(N2CCNC2=O)cc1)c1ccc(Cl)s1,,C1CCOC1,,O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3],,test
US05346925,CC1=Cc2ccccc2C1[Zr](C)(C)(=[SiH2])C1C(C)=Cc2ccccc21.[Cl-].[Cl-]>>CC1=CC2=C(CCCC2)C1[Zr](C)(C)(=[SiH2])C1C(C)=CC2=C1CCCC2.[Cl-].[Cl-],O=[Pt],ClCCl,,[H][H],,test
US20040072840A1,BrCCOC1CCCCO1.Cc1ccc(CC#N)cc1C>>Cc1ccc(C(C#N)CCOC2CCCCO2)cc1C,,C1CCOC1,,[H-].[Na+],,test
US20050130954A1,CC(C)(C)OC(=O)N1CCN(c2ncnc(C#C[Si](C)(C)C)c2N)CC1>>CC(C)(C)OC(=O)N1CCN(c2ncnc3cc[nH]c23)CC1,,CN1CCCC1=O,,CC(C)(C)O[K],,test
US04576629,COC(CN(C)C(=O)Nc1nnc(S)s1)OC>>CN1CC(O)N(c2nnc(S)s2)C1=O,,O,,Cl,,test
US04940710,CCn1cc(C(=O)O)c(=O)c2cc(F)c(F)c(F)c21.FC(F)C1CNCCN1>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C(F)F)C3)c(F)c21,,c1ccncc1,,,,test
US20060019985A1,CC(C)(C)OC(=O)N1CCC2(CCNC2)CC1.CCOC(=O)c1cc(C2CC2)c2c(C)c(Cl)c(F)cn2c1=O>>CCOC(=O)c1cc(C2CC2)c2c(C)c(N3CCC4(CCN(C(=O)OC(C)(C)C)CC4)C3)c(F)cn2c1=O,,CC#N,,O=C([O-])O.[Na+],,test
US09034884B2,C[C@@H]1CCCN1.C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C(CC#N)CN4CCC(Oc5cc(F)cc(C=O)c5)C(F)C4)c3)ncnc21>>C[C@@H]1CCCN1Cc1cc(F)cc(OC2CCN(CC(CC#N)n3cc(-c4ncnc5[nH]ccc45)cn3)CC2F)c1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20080015191A1,COc1cc(N)cc(OC)c1OC.Clc1cncc(Oc2ccccc2Cl)n1>>COc1cc(Nc2cncc(Oc3ccccc3Cl)n2)cc(OC)c1OC,,C1CCCCC1,CCOC(C)=O,,,test
US20130143877A1,COc1ccc2c(c1)C(C)(C)c1[nH]c3cc(Br)ccc3c1C2=O.N#C[Cu]C#N>>COc1ccc2c(c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O,,CCOC(C)=O,CN1CCCC1=O,,,test
US20070135623A1,CC1=C(C)C([Si](C)(C)Cl)c2sccc21.Cc1cc(Br)cc(C)c1N>>CC1=C(C)C([Si](C)(C)Nc2c(C)cc(Br)cc2C)c2sccc21,,C1CCOC1,,[Li]CCCC,,test
US05624923,Cc1ccccc1C(=O)Nc1ccc(C(=O)Cl)cc1.c1ccc2c(c1)NCc1cccn1-2>>Cc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3-c3ccccc32)cc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20150191452A1,F[C@@H]1CNCC[C@@H]1c1ccc(OCc2ccccc2)cc1>>Oc1ccc([C@H]2CCNC[C@H]2F)cc1,[Pd],CC(C)O,,,,test
US20080108608A1,Cn1nc(C2CC2)cc1N.O=C(Nc1ncc(Br)s1)Oc1ccccc1>>Cn1nc(C2CC2)cc1NC(=O)Nc1ncc(Br)s1,,C1CCOC1,,CCN(CC)CC,,test
US20070244159A1,COC(=O)C1(c2ccc3oc(=O)[nH]c3c2)CC1>>O=C(O)C1(c2ccc3oc(=O)[nH]c3c2)CC1,,CO,O,[Li]O,,test
US20100331326A1,COC(=O)c1cc(Br)ccc1F.Cc1ccncc1N1CCNC1=O>>COC(=O)c1cc(N2CCN(c3cnccc3C)C2=O)ccc1F,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US06498251B1,CC(C)(C)OC(=O)N1CCc2sc(C(=O)O)cc2C1.CI>>COC(=O)c1cc2c(s1)CCN(C(=O)OC(C)(C)C)C2,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20160130254A1,N#Cc1ccc(NC2CCCC(O)C2)cc1C(F)(F)F>>N#Cc1ccc(NC2CCCC(=O)C2)cc1C(F)(F)F,,CS(C)=O,,CCN(CC)CC,,test
US20110245242A1,O=C1C=CC(=O)N1c1ccc(Cl)c([N+](=O)[O-])c1>>Nc1cc(N2C(=O)CCC2=O)ccc1Cl,[Pd],C1CCOC1,,[H][H],,test
US20070219237A1,C1COCCN1.Cc1nc2c(NC3CCOc4ccccc43)cc(C(=O)O)cn2c1CO>>Cc1nc2c(NC3CCOc4ccccc43)cc(C(=O)N3CCOCC3)cn2c1CO,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090318690A1,CC(C)(C)OC(=O)N1CCC(CCc2noc3c(CO)c(OCc4ccc(F)cc4)ccc23)CC1>>OCc1c(OCc2ccc(F)cc2)ccc2c(CCC3CCNCC3)noc12,,C1CCOC1,CO,CS(=O)(=O)O,,test
US04209515,C1COCCN1.O=C(O)c1nc(CCl)n(-c2ccc(Cl)cc2C(=O)c2ccccc2Cl)n1>>Cl.O=C(O)c1nc(CN2CCOCC2)n(-c2ccc(Cl)cc2C(=O)c2ccccc2Cl)n1,,CCO,,[I-].[Na+],,test
US20070203116A1,COc1cccc(CCc2ccc(Br)cc2CO)c1C.II>>COc1cccc(CCc2ccc(Br)cc2CI)c1C,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120172345A1,CC(=O)Nc1cc(-c2cc(C(=O)c3ccc(Cl)cc3)c(-c3ncn(COCC[Si](C)(C)C)n3)s2)ccn1.CN1CCC(Cl)CC1>>CC(=O)Nc1cc(-c2cc(C(O)(c3ccc(Cl)cc3)C3CCN(C)CC3)c(-c3ncn(COCC[Si](C)(C)C)n3)s2)ccn1,,C1CCOC1,,[Mg],,test
US20140256725A1,COC(=O)c1ccc([N+](=O)[O-])cc1Br.OB(O)c1ccccc1F>>COC(=O)c1ccc([N+](=O)[O-])cc1-c1ccccc1F,,ClCCl,,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20130317231A1,COc1ccc(C2CC(c3cc(OC)c(OC)c(OC)c3)=NN2C(C)=O)cc1OCC(=O)O.Nc1nc2ccccc2s1>>COc1ccc(C2CC(c3cc(OC)c(OC)c(OC)c3)=NN2C(C)=O)cc1OCC(=O)Nc1nc2ccccc2s1,,ClCCl,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20150119395A1,C=C[Mg]Br.COc1ccc(COc2cc(OCc3ccc(OC)cc3)c(C(C)C)cc2C=O)cc1>>C=CC(O)c1cc(C(C)C)c(OCc2ccc(OC)cc2)cc1OCc1ccc(OC)cc1,,C1CCOC1,,,,test
US04021461,CC(C)=CCC(C)C=O>>CC(C)CCC(C)C=O,[Pd],,,,,test
US20090042841A1,CCOC(=O)C1CCN(c2ncccc2[N+](=O)[O-])CC1>>O=C(O)C1CCN(c2ncccc2[N+](=O)[O-])CC1,,CO,O,Cl,[K+].[OH-],test
US05545734,CCC1C=C(C)C(O)C(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(O[Si](C)(C)C(C)(C)C)C(OC)C3)C(C)C(O[Si](C)(C)C(C)(C)C)CC1=O)C(C)CC2OC.CCN(CC)S(F)(F)F>>CCC1C=C(C)C(F)C(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(O)C(OC)C3)C(C)C(O)CC1=O)C(C)CC2OC,,ClCCl,,CCOC(C)=O,O=C([O-])O.[Na+],test
US20090062363A1,NC(N)=NC(=O)c1ccc2c(c1)c(C=O)cn2Cc1ccccc1>>NC(N)=NC(=O)c1ccc2c(c1)c(CO)cn2Cc1ccccc1,,CO,,[BH4-].[Na+],,test
US20120238574A1,Cc1cc(F)c([N+](=O)[O-])cc1F.O=C1CCC(=O)N1Br>>O=[N+]([O-])c1cc(F)c(CBr)cc1F,O=C(OOC(=O)c1ccccc1)c1ccccc1,Clc1ccccc1,,,,test
US20110237791A1,O=C(c1ccccc1)C(F)(F)Cl.Oc1ccc(Br)cc1Cl>>FC(F)Oc1ccc(Br)cc1Cl,,CC#N,,[K+].[OH-],,test
US20120225844A1,CC(=O)OCc1cc2n(n1)CCN(c1ccc(F)cn1)C2=O>>O=C1c2cc(CO)nn2CCN1c1ccc(F)cn1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20100009973A1,COC(=O)c1ccc(CN)cc1.N#Cc1c(-c2ccoc2)cc(-c2cccs2)nc1OS(=O)(=O)C(F)(F)F>>COC(=O)c1ccc(CNc2nc(-c3cccs3)cc(-c3ccoc3)c2C#N)cc1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20070161684A1,CCC(C)(C)NC(=O)c1ccc(-c2cc(C(=O)NC3CC3)cc(F)c2C)nc1.O=C(OO)c1cccc(Cl)c1>>CCC(C)(C)NC(=O)c1ccc(-c2cc(C(=O)NC3CC3)cc(F)c2C)[n+]([O-])c1,,CO,ClC(Cl)Cl,,,test
US20100130474A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(-c2ccc(Cl)cc2)n[nH]1>>CC(C)(C)OC(=O)n1nc(-c2ccc(Cl)cc2)cc1N,,ClCCl,,,,test
US20140187553A1,COC(=O)c1cc(C2CC2)nc(-c2cn(S(=O)(=O)c3ccc(C)cc3)c3ccc(-c4nnc(NC(C)C)o4)cc23)n1>>CC(C)Nc1nnc(-c2ccc3[nH]cc(-c4nc(C(=O)O)cc(C5CC5)n4)c3c2)o1,,C1COCCO1,,[Na+].[OH-],,test
US20130072690A1,CCOC(=O)C1CC2(CCOCC2)CN1.O=C(Cl)OCc1ccccc1>>CCOC(=O)[C@@H]1CC2(CCOCC2)CN1C(=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20030204083A1,CN(C)C=Nc1nc(NC(CCCc2ccccc2)C2CC2)nc(C(C)(C)F)n1.NO>>CC(C)(F)c1nc(NC=NO)nc(NC(CCCc2ccccc2)C2CC2)n1,,CO,,Cl,,test
US20080138912A1,BrCc1ccccc1.CCCCCCCCCCCCOc1cc(Br)c(O)cc1Br>>CCCCCCCCCCCCOc1cc(Br)c(OCc2ccccc2)cc1Br,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20080269280A1,COCCNCC(=O)N1CC(=O)N(c2cccc(Cl)c2C)C1.N#Cc1cccc(C(=O)Cl)c1>>COCCN(CC(=O)N1CC(=O)N(c2cccc(Cl)c2C)C1)C(=O)c1cccc(C)c1,,CN1CCCC1=O,,,,test
US20110237584A1,C[Si](C)(C)C(F)(F)F.O=Cc1ccccn1>>OC(c1ccccn1)C(F)(F)F,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04459152,O.O=[N+]([O-])c1cc(CS(=O)(=O)Cc2ccc(Cl)c([N+](=O)[O-])c2)ccc1Cl.[OH-]>>O=[N+]([O-])c1cc(CS(=O)(=O)Cc2ccc(O)c([N+](=O)[O-])c2)ccc1O,,O,,O=S(=O)(O)O,,test
US05686458,COc1cccc2c(N3CCc4ccccc4C3C)nc(Cl)nc12.Nc1ccc(F)cc1>>COc1cccc2c(N3CCc4ccccc4C3C)nc(Nc3ccc(F)cc3)nc12.Cl,,CN(C)C=O,,,,test
US20090054435A1,C=CCOC(=O)[C@H](C)O.COc1ccc(C(=O)c2ccc(OCCc3nc(-c4ccccc4)oc3C)nc2)c(O)c1>>C=CCOC(=O)[C@@H](C)Oc1cc(OC)ccc1C(=O)c1ccc(OCCc2nc(-c3ccccc3)oc2C)nc1,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090318511A1,COc1cccc(S(=O)(=O)N(CCC(C)C)[C@@H](C(=O)OCc2ccccc2)C(C)(C)C)c1>>COc1cccc(S(=O)(=O)N(CCC(C)C)[C@@H](C(=O)O)C(C)(C)C)c1,[Pd],CO,,[H][H],,test
US20100022550A1,CC(C)C(=O)NC1CCc2[nH]c3ccc(C#N)cc3c2C1.Fc1ccc(CCl)nc1>>CC(C)C(=O)NC1CCc2c(c3cc(C#N)ccc3n2Cc2ccc(F)cn2)C1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20120208800A1,COc1cc2c(N[C@H](C)c3ccccc3)c([N+](=O)[O-])cnc2cc1-c1c(C)noc1C>>COc1cc2c(N[C@H](C)c3ccccc3)c(N)cnc2cc1-c1c(C)noc1C,,CCO,Cl,,,test
US04638000,CCOC(=O)C(CCCCC1CCN(C(=O)OCc2ccccc2)CC1)OS(C)(=O)=O.N[C@H]1CSc2ccccc2NC1=O>>CCOC(=O)C(CCCCC1CCN(C(=O)OCc2ccccc2)CC1)N[C@H]1CSc2ccccc2NC1=O,,CCOC(C)=O,,,,test
US20020161041A1,COCOc1ccc(C2CCCC(=O)C2)c(OCOC)c1>>O=C1CCCC(c2ccc(O)cc2O)C1,,CO,,,,test
US20050065020A1,CC1CO1.CCCCn1ccnc1.Cl>>CCCCn1cc[n+](CC(C)O)c1.[Cl-],,CCO,,,,test
US20130196974A1,CC(=O)NC1(C)CCN(c2cc(N3CCS(=O)(=O)c4ccccc4C3)nc3ccc(C)cc23)C1>>Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(N3CCC(C)(N)C3)c2c1,,ClCCl,,Cl,O=C([O-])[O-].[K+].[K+],test
US20040209892A1,O=[N+]([O-])c1ccc(Oc2ccnc3ccccc23)cc1[N+](=O)[O-]>>Nc1ccc(Oc2ccnc3ccccc23)cc1N,[Zn],C1CCOC1,,CC(=O)O,,test
US20150266870A1,CC(C)(C)[Si](OCCOc1ccc([N+](=O)[O-])nc1)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](C)(C)OCCOc1ccc(N)nc1,[Pd],CO,,,,test
US20070197626A1,CC(C)(C)OC(=O)CBr.CCOC(=O)Cc1ccc(O)c(OCC)c1>>CCOC(=O)Cc1ccc(OCC(=O)OC(C)(C)C)c(OCC)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130011361A1,COC(=O)c1cc(N)nn1Cc1ccc(OC)cc1.O=C=NCCCl>>COC(=O)c1cc(NC(=O)NCCCl)nn1Cc1ccc(OC)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20050222410A1,CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1cnc(N2CCN(C(=O)OC(C)(C)C)CC2)nc1>>Nc1ccccc1NC(=O)c1cnc(N2CCNCC2)nc1,,C1COCCO1,CCOCC,Cl,,test
US20110172442A1,COC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)c1cc2ccccc2o1>>COc1ccc(C[C@H](NC(=O)c2cc3ccccc3o2)C(=O)O)cc1,,CO,,[Na+].[OH-],,test
US04996318,O=[N+]([O-])c1cccnc1N1CCNCC1>>Nc1cccnc1N1CCNCC1,,CCO,,Cl,,test
US20030069276A1,CNC(=O)N(Cc1ccccc1)C1CCN(Cc2nc[nH]c2C)CC1.II>>CNC(=O)N(Cc1ccccc1)C1CCN(Cc2nc(I)[nH]c2C)CC1,,ClCCl,O,[Na+].[OH-],,test
US20040259916A1,CCO.COCC1(c2ccc(NC(=O)c3ccccc3N(Cc3ccncc3)C(C)=O)cc2)CC1>>COCC1(c2ccc(NC(=O)c3ccccc3NCc3ccncc3)cc2)CCC1,,CCO,,Cl,O=C([O-])O.[Na+],test
US06472386B1,COc1cc(B(O)O)cc(OC)c1OC.O=Cc1ccc(Cl)s1>>COc1cc(-c2ccc(C=O)s2)cc(OC)c1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,CCOC(C)=O,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20090093483A1,Cc1c(Cl)cccc1I.O=C1CCC(=O)N1Br>>Clc1cccc(I)c1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US05866573,C=CCNC(C)C#N.O=C(Cl)C(=O)Cl>>C=CCn1c(C)c(Cl)nc(Cl)c1=O,,Clc1ccccc1Cl,,Cl,,test
US20070191333A1,CC(C)(C)OC(=O)NC[C@@H]1CNC[C@H]1F.Cc1c(F)c(F)cc2c(=O)n(N)c(=O)n(C3CC3)c12>>Cc1c(N2CC(F)C(CNC(=O)OC(C)(C)C)C2)c(F)cc2c(=O)n(N)c(=O)n(C3CC3)c12,,CS(C)=O,O,CCN(CC)CC,,test
US20080021069A1,Cl.FC(F)(F)Oc1ccc(-n2c(SCc3ccc(Cl)cc3)nc3cc(Cl)ccc32)cc1>>Cl.FC(F)(F)Oc1ccc(-n2c(SCc3ccc(Cl)cc3)nc3cc(Cl)ccc32)cc1,,CCOCC,,CCOC(C)=O,,test
US06469167B1,COC(=O)COc1ccc(CC2SC(=O)NC2=O)cc1>>O=C(O)COc1ccc(CC2SC(=O)NC2=O)cc1,,O,,Cl,[Na+].[OH-],test
US06271234B1,COc1cc(N)ccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1.O=CO>>COc1cc(NC=O)ccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1,,CCOC(C)=O,,,,test
US20130165446A1,CCCc1nc2c(C)cc(-c3nc4ccc(N(C)CCOc5ccc([N+](=O)[O-])c(N(C)C(=O)OC(C)(C)C)c5)cc4n3C)cc2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1>>CCCc1nc2c(C)cc(-c3nc4ccc(N(C)CCOc5ccc(N)c(N(C)C(=O)OC(C)(C)C)c5)cc4n3C)cc2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,CO,,,,test
US20140094462A1,O=C(C[C@@H]1CC=CCCC(=O)O[C@H](c2ccccc2)CNC1=O)NCc1ccc(Cl)cc1.O=C(OO)c1cccc(Cl)c1>>O=C(C[C@@H]1C[C@H]2O[C@@H]2CCC(=O)O[C@H](c2ccccc2)CNC1=O)NCc1ccc(Cl)cc1,,ClCCl,,,,test
US20100179150A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C1=C(O)CCNC1>>COC(=O)C1=C(O)CCN(C(=O)OC(C)(C)C)C1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20120171245A1,C[Si](C)(C)N=[N+]=[N-].N#C[C@@H]1CCC[C@H](Nc2nc(-c3c[nH]c4ncc(Cl)cc34)ncc2F)C1>>Fc1cnc(-c2c[nH]c3ncc(Cl)cc23)nc1N[C@H]1CCC[C@@H](c2nnn[nH]2)C1,,Cc1ccccc1,,CCCC[Sn](=O)CCCC,,test
US20150333274A1,CC1(C)c2ccccc2-c2ccc(-n3c4ccccc4c4cc(Br)ccc43)cc21.COB(OC)OC>>CC1(C)c2ccccc2-c2ccc(-n3c4ccccc4c4cc(B(O)O)ccc43)cc21,,C1CCOC1,,[Li]CCCC,,test
US20070003539A1,COc1ccc(B(O)O)cc1OC.NC(=O)c1cccc(N)c1.O=CC(=O)O>>COc1ccc(C(Nc2cccc(C(N)=O)c2)C(=O)O)cc1OC,,CC#N,CN(C)C=O,O,,test
US20070185092A1,CSCCOc1cccn(-c2ccc(-n3cc(CNC(=O)c4ccc(Cl)s4)nn3)cc2)c1=O.O=S([O-])OO>>CS(=O)CCOc1cccn(-c2ccc(-n3cc(CNC(=O)c4ccc(Cl)s4)nn3)cc2)c1=O,,O,,CO,,test
US05789434,C=CCOC(=O)CC(=O)OCC=C.O=C1c2ccccc2C(=O)N1CCBr>>C=CCOC(=O)C(CCN1C(=O)c2ccccc2C1=O)C(=O)OCC=C,,C1CCOC1,,[H-].[Na+],,test
US05232939,CC(=O)C(C#N)c1ccc(NC(=O)OC(C)(C)C)cc1.CCOC(CNN)OCC.Cl>>Cc1nn2cc[nH]c2c1-c1ccc(N)cc1.Cl,,C1COCCO1,CCOC(C)=O,CCO,,test
US20150307493A1,CI.CS(=O)(=O)c1cc(Br)c2c(c1)NC(=O)C1(CC1)O2>>CN1C(=O)C2(CC2)Oc2c(Br)cc(S(C)(=O)=O)cc21,,CN(C)C=O,,[H-].[Na+],,test
US05166151,CC(C)CCON=O.c1ccc(C2=NCc3cncnc3-c3ccccc32)cc1>>ON=c1nc(-c2ccccc2)c2ccccc2c2ncncc12,,C1CCOC1,,CC(C)(C)O,CC(C)(C)[O-].[K+],test
US06207686B1,CC[C@H]1CN2CC[C@H]1C[C@H]2[C@H](O)c1ccnc2ccc(OC)cc12.O=C(O)C(c1ccccc1OCc1ccccc1)C(O)C1CCCCC1>>CC[C@H]1CN2CC[C@H]1C[C@H]2[C@H](O)c1ccnc2ccc(OC)cc12.O=C(O)[C@@H](c1ccccc1OCc1ccccc1)[C@@H](O)C1CCCCC1,,ClCCl,,,,test
US20080221148A1,Clc1ccc(CBr)cc1.O=Cc1ccc(O)c(Cl)c1>>O=Cc1ccc(OCc2ccc(Cl)cc2)c(Cl)c1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20130289033A1,O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(I)c1.OB(O)c1ccccc1Cl>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(-c2ccccc2Cl)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20140018533A1,CCOC(=O)C1=C(Nc2ccc(F)cc2F)OC(=Cc2c[nH]c3ncccc23)C1=O>>O=C1C=C(Nc2ccc(F)cc2F)OC1=Cc1c[nH]c2ncccc12,,CN(C)C=O,,,,test
US20140179676A1,Cc1cc(Br)ccc1C=O.Cn1nc(-c2ccccn2)cc1N>>Cc1cc(Br)ccc1C=C1C(=N)N(C)N=C1c1ccccn1,,CC#N,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20140336190A1,Cc1noc(C)c1-c1cc(C(O)[C@@H]2CCC3(CC3)O2)c2nc(C3CC3)n(C(=O)OC(C)(C)C)c2c1>>Cc1noc(C)c1-c1cc(C(=O)[C@@H]2CCC3(CC3)O2)c2nc(C3CC3)n(C(=O)OC(C)(C)C)c2c1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04379092,O=C(O)c1ccccc1C(=O)c1ccccc1>>O=C1c2ccccc2C(=O)c2ccccc21,,O=S(=O)(O)O,,O,,test
US20100010053A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCC(=O)OC(C)(C)C)cn(C)c34)no2)cc1Cl>>CC(C)Oc1ccc(-c2nc(-c3cccc4c(CCC(=O)O)cn(C)c34)no2)cc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050130954A1,CC(C)(C)OC(=O)C(N)C=O.N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(c2ncnc3ccccc23)CC1>>NCCN[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(c2ncnc3ccccc23)CC1,,CO,,[BH4-].[Na+],,test
US20090270374A1,C=CCI.O=c1[nH]c2cc(Cl)ccc2s1>>C=CCn1c(=O)sc2ccc(Cl)cc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120202781A1,O=C(NC1CCc2cc(Cc3cc(CO)cc(C(F)(F)F)c3)ccc21)OCc1ccccc1>>NC1CCc2cc(Cc3cc(CO)cc(C(F)(F)F)c3)ccc21,[Pd],CCO,,,,test
US20100152187A1,Cc1nc(N)sc1C(=O)NCc1ccccc1.O=C=Nc1ccccc1>>Cc1nc(NC(=O)Nc2ccccc2)sc1C(=O)NCc1ccccc1,,C1CCOC1,CCOCC,CCN(CC)CC,,test
US20130156700A1,FC(F)(F)c1cnc(Cl)nc1NC1CC1.Nc1cc(F)c(C(=O)N2CCOCC2)cc1O>>O=C(c1cc(O)c(Nc2ncc(C(F)(F)F)c(NC3CC3)n2)cc1F)N1CCOCC1,,CCCCO,,Cl,,test
US20150018547A1,COc1ccc(CSc2cc(F)cc(OC)c2)cc1>>COc1cc(F)cc(S)c1,,O=C(O)C(F)(F)F,,COc1ccccc1,,test
US08129361B2,CC(C)(C)OC(=O)NC1(CCc2ccc(OCCCc3cccc(OC(F)(F)F)c3)c(C(F)(F)F)c2)COC(C)(C)OC1.Cl>>Cl.NC(CO)(CO)CCc1ccc(OCCCc2cccc(OC(F)(F)F)c2)c(C(F)(F)F)c1,,CCO,,,,test
US04096143,NN.O=C(O)c1ccc(Cl)cc1C(Cl)Cl>>O=c1[nH]ncc2cc(Cl)ccc12,,CCO,,O,,test
US05344830,CC(C)(C)OC(=O)NCCN.O=C(CBr)OCc1ccccc1>>CC(C)(C)OC(=O)NCCNCC(=O)OCc1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20110117073A1,CN1CCNCC1.Cc1cc(Nc2cc(Cl)nc(Sc3ccc(NC(=O)OC(C)(C)C)cc3)n2)[nH]n1>>Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Sc3ccc(NC(=O)OC(C)(C)C)cc3)n2)[nH]n1,,CCOC(C)=O,,,,test
US20100197678A1,O=[N+]([O-])c1ccccc1NC(c1ccc2c(cnn2-c2ccc(F)cc2)c1)C(F)(F)F>>Nc1ccccc1NC(c1ccc2c(cnn2-c2ccc(F)cc2)c1)C(F)(F)F,[Zn],CO,,Cl,O=C([O-])O.[Na+],test
US20160052898A1,CC(Cl)C(=O)Cl.COc1ccc(NC(=O)c2ccc(-c3ccccc3)cc2)cc1N>>COc1ccc(NC(=O)c2ccc(-c3ccccc3)cc2)cc1NC(=O)C(C)Cl,,Cc1ccccc1,,,,test
US20090124655A1,NCCc1ccc(Cl)c(Cl)c1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NCCc1ccc(Cl)c(Cl)c1)C(F)(F)F,,C1CCOC1,,,,test
US09138427B2,CCOC(=O)CCC(=O)CCC(=O)c1ccc(F)cc1.Cc1ncc[nH]1>>CCOC(=O)CCC(=O)CCC(=O)c1ccc(-n2ccnc2C)cc1,,O,,CS(C)=O,,test
US20150166564A1,O=Nc1c(-c2ccccc2)nn2ccccc12>>Nc1c(-c2ccccc2)nn2ccccc12,[Zn],CCO,CO,Cl,,test
US20020156081A1,Cc1cccc(NC(=O)Nc2ccc(-c3nn(C4CCN(C(=O)CN(C)C(=O)OC(C)(C)C)CC4)c4ncnc(N)c34)cc2F)c1>>CNCC(=O)N1CCC(n2nc(-c3ccc(NC(=O)Nc4cccc(C)c4)c(F)c3)c3c(N)ncnc32)CC1,,CC(C)=O,,Cl,,test
US20060229353A1,CCCCCC(O)C1C(=O)NC2(C(O)C3C=CCCC3)C(=O)OC12C.SCc1ccccc1>>CCCCCC(O)C1C(=O)NC(C(=O)SCc2ccccc2)(C(O)C2C=CCCC2)C1(C)O,,ClCCl,,CCN(CC)CC,,test
US20120020884A1,O=C(Cl)C(=O)Cl.O=C(O)C1CCCc2c1c1ccccc1n2CCF>>O=C(Cl)C1CCCc2c1c1ccccc1n2CCF,,ClCCl,,CN(C)C=O,,test
US20150259354A1,N#Cc1c(-c2ccc(Oc3ccccc3)cc2)nn2c1NCCC2c1cccc(N)c1.OO>>NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c1NCCC2c1cccc(N)c1,,CCO,CS(C)=O,[Na+].[OH-],,test
US20070054909A1,C1CCOC1.CC(C)(C)OC(=O)N1CC(O)C[C@@]1(C)C(=O)O.Oc1ccc(F)cc1F>>COC(=O)C1CC(Oc2ccc(F)cc2F)CN1C(=O)OC(C)(C)C,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05587486,Cc1[nH]c2ccccc2c1C=O.Nc1ccccc1>>Cc1[nH]c2ccccc2c1C=N,,Cc1ccccc1,,CCCCCC,,test
US20020128247A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)[Si](C)(C)OC(CNCCO)c1ccc(Cl)nc1>>CC(C)(C)OC(=O)N(CCO)CC(O[Si](C)(C)C(C)(C)C)c1ccc(Cl)nc1,,C1CCOC1,,,,test
US04055596,CCOC(=O)CCCCCCN(CCCC(O)COc1ccc(F)cc1)S(C)(=O)=O>>CS(=O)(=O)NCCCC(O)COc1ccc(F)cc1,,CCO,,O,[Na+].[OH-],test
US20130045942A1,Cc1ccc(C=NO)o1.Cl>>Cc1ccc(CN)o1.Cl,[Pd],CCO,,,,test
US20030199491A1,COCCOc1cc2nccc(Cl)c2cc1C#N.Cc1cc2c(F)c(O)ccc2[nH]1>>COCCOc1cc2nccc(Oc3ccc4[nH]c(C)cc4c3F)c2cc1C#N,,CN(C)C=O,,,,test
US20160251339A1,C=O.COc1ccc(S(=O)(=O)n2cc(C(F)F)c3cc(Br)ccc32)cc1N1CCNCC1>>COc1ccc(S(=O)(=O)n2cc(C(F)F)c3cc(Br)ccc32)cc1N1CCN(C)CC1,,CO,,[BH3-]C#N.[Na+],,test
US20150322019A1,NC1CCN(Cc2ccccc2)CC1.O=C(O)c1cnc2nc1NCCCCc1cn(nn1)CCCCCCN2>>O=C(NC1CCN(Cc2ccccc2)CC1)c1cnc2nc1NCCCCc1cn(nn1)CCCCCCN2,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20150307476A1,C[C@@H](Oc1cc(-c2cnn(C3CCN(NC(=O)OC(C)(C)C)CC3)c2)cnc1NC(=O)OC(C)(C)C)c1c(Cl)ccc(F)c1Cl>>C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl,,ClCCl,,CCO,Cl,test
US20100183603A1,O=C1NC(=O)C(c2c[nH]c3ccc(Br)cc23)=C1c1cc2c3c(ccn3CCC2)c1>>O=C1NC(=O)[C@@H](c2cc3c4c(ccn4CCC3)c2)[C@@H]1c1c[nH]c2ccc(Br)cc12,,CO,O,Cl,[Mg],test
US20140315879A1,CC(C)Oc1ncc(O)cc1Cl.CN(C)S(=O)(=O)NC(=O)c1cc(F)c(CBr)cc1F>>CC(C)Oc1ncc(OCc2cc(F)c(C(=O)NS(=O)(=O)N(C)C)cc2F)cc1Cl,,CS(C)=O,O,CC(=O)O,O=C([O-])[O-].[K+].[K+],test
US20040097555A1,Cc1cc(C)cc(-c2nc(N)sc2-c2ccncc2)c1.O=C(Cl)Cc1ccccc1>>Cc1cc(C)cc(-c2nc(NC(=O)Cc3ccccc3)sc2-c2ccncc2)c1,CN(C)c1ccncc1,CC(=O)N(C)C,,O=C([O-])O.[Na+],,test
US20120157487A1,O=S(=O)(Nc1cc(Cl)ccc1SSc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1)c1ccc(Cl)c(C(F)(F)F)c1>>O=S(=O)(Nc1cc(Cl)ccc1S)c1ccc(Cl)c(C(F)(F)F)c1,,C1CCOC1,O,Cl,[BH4-].[Na+],test
US20140011802A1,C[C@H]1OC[C@@](N)(c2ccc(F)cc2F)[C@@H]1CO.O=C(N=C=S)c1ccccc1>>C[C@H]1OC[C@@](NC(=S)NC(=O)c2ccccc2)(c2ccc(F)cc2F)[C@@H]1CO,,ClCCl,,,,test
US20090298815A1,CS(=O)(=O)N1CCC(N)CC1.O=S(=O)(Nc1cc(-c2nc(C3CCC3)sc2-c2ccnc(Cl)n2)ccc1F)c1cc(F)ccc1F>>CS(=O)(=O)N1CCC(Nc2nccc(-c3sc(C4CCC4)nc3-c3ccc(F)c(NS(=O)(=O)c4cc(F)ccc4F)c3)n2)CC1,,C1CCOC1,,,,test
US06251917B1,BrCc1ccc2ccccc2c1.COC(=O)c1ccccc1O>>COC(=O)c1ccccc1OCc1ccc2ccccc2c1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20080076771A1,CO.O=C(O)c1ccc(Nc2cc(OC3CC3)ncn2)cc1>>COC(=O)c1ccc(Nc2cc(OC3CC3)ncn2)cc1,,C1COCCO1,,O,O=S(Cl)Cl,test
US20040235872A1,Cc1cc2cc(N)cc(I)c2[nH]1.N#C[N-]C#N>>Cc1cc2cc(NC(N)=NC#N)cc(I)c2[nH]1,,CN(C)C=O,,Cl,,test
US04197296,CCO.C[C@]12CC(=O)[C@H]3[C@@H](CC[C@H]4C[C@@H]5O[C@@H]5C[C@@]43C)[C@@H]1CCC2=O>>CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CCC(=O)[C@@]4(C)CC(=O)[C@@H]32)C[C@@H]1O,O=S(=O)(O)O,,,O=C([O-])O.[Na+],,test
US20150038528A1,CC(C)(C)OC(=O)N[C@@H](CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(=O)O>>N#Cc1nc(C(=O)NC[C@H](N)C(=O)O)c(O)c2ccc(Oc3ccccc3)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120232083A1,Brc1ncccn1.CC1(C)OB(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)OC1(C)C>>CC1(C)OB(c2ccc(-c3ncccn3)cc2)OC1(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20140187553A1,Cc1ccc(S(=O)(=O)n2cc(-c3cncc(OC(C)C)n3)c3cc(-c4noc(N)n4)ccc32)cc1>>CC(C)Oc1cncc(-c2c[nH]c3ccc(-c4noc(N)n4)cc23)n1,,C1COCCO1,,[Na+].[OH-],,test
US20120165320A1,CC(=O)NC[C@H]1CN(c2ccc(C34CNCC3C4)cc2)C(=O)O1.COC(=O)Cl>>COC(=O)N1CC2CC2(c2ccc(N3C[C@H](CNC(C)=O)OC3=O)cc2)C1,,ClCCl,,CCN(CC)CC,,test
US20080009435A1,CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1>>CC(C)C[C@H](N)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1,,C1COCCO1,,CCOC(C)=O,Cl,test
US06410556B1,CC(C)(C)OC(=O)c1c(NC(=O)OCc2ccccc2)sc2c1C[C@@H](CN1Cc3ccccc3C1=O)N(C(=O)OC(C)(C)C)C2>>CC(C)(C)OC(=O)c1c(N)sc2c1C[C@@H](CN1Cc3ccccc3C1=O)N(C(=O)OC(C)(C)C)C2,[Pd],CO,,,,test
US04381297,CCCCCC(=O)CC(CCc1ccccc1)P(=O)(CC(=O)OC)OCC>>CCCCCC(=O)CC(CCc1ccccc1)P(=O)(CC(=O)O)OCC,,CC(=O)O,,Cl,,test
US20050096336A1,Cc1ncc(-c2ccc(C(F)(F)F)cc2)cn1.O=C1CCC(=O)N1Br>>FC(F)(F)c1ccc(-c2cnc(CBr)nc2)cc1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20040034232A1,COC(=O)c1ccc(C(=O)N(CC(=O)Nc2ccc(-c3csc(N)n3)cc2)c2ccc(OC)cc2)cc1.[Na+]>>COc1ccc(N(CC(=O)Nc2ccc(-c3csc(N)n3)cc2)C(=O)c2ccc(C(=O)[O-])cc2)cc1.[Na+],,CO,,Cl,,test
US20030120064A1,CC(=O)O[C@@H]1O[C@H](COC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1.COC(=O)c1nc[nH]n1>>COC(=O)c1ncn([C@@H]2O[C@H](COC(=O)c3ccccc3)[C@@H](OC(=O)c3ccccc3)[C@H]2OC(=O)c2ccccc2)n1,Cc1ccc(S(=O)(=O)O)cc1,,,,,test
US20110306606A1,CC#N.CCCCc1ccc(Nc2nc(Cl)ccc2[N+](=O)[O-])cc1>>NCCCn1ccnc1,,CC#N,,CCN(CC)CC,,test
US20140364427A1,O=C(CO)c1ccccc1.O=Cc1ccccc1>>O=C1CCOc2ccccc21,,CO,,C1CCNC1,,test
US20130029968A1,CC(C)(C)OC(=O)N1CCc2nc(I)[nH]c2CC1.C[Si](C)(C)CCOCCl>>CC(C)(C)OC(=O)N1CCc2nc(I)n(COCC[Si](C)(C)C)c2CC1,,C1CCOC1,,[H-].[Na+],,test
US05962490,CCCc1ccc(-c2ccc(S(=O)(=O)Cl)s2)cc1.Cc1noc(N)c1Br>>CCCc1ccc(-c2ccc(S(=O)(=O)Nc3onc(C)c3Br)s2)cc1,,CO,ClC(Cl)Cl,,,test
US20040082607A1,CCCCOc1c(CNC(=O)OC(C)(C)C)n(CC(C)(C)C)c(=O)c2ccc(OCC)cc12.Cl>>CCCCOc1c(CN)n(CC(C)(C)C)c(=O)c2ccc(OCC)cc12.Cl,,CCOC(C)=O,,,,test
US20060024330A1,CC(C)(C)OC(=O)N1CCC(Cc2c(O)c(O)c3n(c2=O)CCN(Cc2ccc(F)cc2)C3=O)CC1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C1c2c(O)c(O)c(CC3CCNCC3)c(=O)n2CCN1Cc1ccc(F)cc1,,ClCCl,,,,test
US04284644,CC(=O)O.Nc1ccc2c(c1)C(=O)C1(CC1)O2>>CC(=O)Nc1ccc2c(c1)C(=O)C1(CC1)O2,,CC(=O)O,,CC(=O)OC(C)=O,,test
US05925655,COC(=O)c1ccc2c(c1)C(=O)N(CCNc1ccccn1)C2>>O=C(O)c1ccc2c(c1)C(=O)N(CCNc1ccccn1)C2,,CO,,[Na+].[OH-],,test
US20020045777A1,BrC(Br)(Br)Br.CN(C(=O)OC(C)(C)C)[C@@H]1CC[C@@H](C=O)CC1>>CN(C(=O)OC(C)(C)C)[C@@H]1CC[C@@H](C=C(Br)Br)CC1,,ClCCl,,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080096877A1,CN(c1cccc2cc(C(=O)NCC3(SCc4ccccc4)CCC4(CC3)OCCO4)[nH]c12)S(=O)(=O)c1cccs1>>CN(c1cccc2cc(C(=O)NCC3(SCc4ccccc4)CCC(=O)CC3)[nH]c12)S(=O)(=O)c1cccs1,,O,,CC(=O)O,,test
US20080139639A1,BrC1CCCCC1.CCOC(=O)c1cc[nH]c1>>CCOC(=O)c1c[nH]c(C2CCCCC2)c1,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100216746A1,Cc1nc(Cl)c(C(=O)O)[nH]1.N#Cc1cc(Cl)cc(Oc2c(F)ccc(CN)c2Cl)c1>>Cc1nc(Cl)c(C(=O)NCc2ccc(F)c(Oc3cc(Cl)cc(C#N)c3)c2Cl)[nH]1,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20060058391A1,O=[N+]([O-])c1cccc(S(=O)(=O)OC[C@H]2CO2)c1.Oc1cc(Br)cc(F)c1F>>Fc1cc(Br)cc(OC[C@H]2CO2)c1F,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110224262A1,BrBr.CCCc1cc(-c2ccccc2)n[nH]1>>CCCc1[nH]nc(-c2ccccc2)c1Br,,ClCCl,,,,test
US20010021713A1,O=C(NCCO)OCc1ccccc1.O=C1c2ccccc2C(=O)N1O>>O=C(NCCON1C(=O)c2ccccc2C1=O)OCc1ccccc1,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150299189A1,BrCC1CCC1.CC(C)(C)OC(=O)c1cc(C2CC2)cnc1Nc1cccc2[nH]ccc12>>CC(C)(C)OC(=O)c1cc(C2CC2)cnc1Nc1cccc2c1ccn2CC1CCC1,,CCOC(C)=O,CN(C)C=O,O,CC(C)(C)[O-].[K+],test
US20050171087A1,O=C(N[C@@H]1CCCN2c3cc(Cl)ccc3Oc3ccccc3[C@H]12)C(F)(F)F>>O=C(N[C@@H]1CCCN2c3ccccc3Oc3ccccc3[C@H]12)C(F)(F)F,[Pd],CN(C)C=O,,,,test
US20140179638A1,CC(C)(C)OC(=O)N1CCCC12CC2.O=C(O)C(F)(F)F>>C1CNC2(C1)CC2.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20040082609A1,COc1cccc(C(=O)N2c3ccccc3C(O)CC2(C)C)c1.Nc1ccccc1>>COc1cccc(C(=O)N2c3ccccc3C(Nc3ccccc3)CC2(C)C)c1,,ClCCl,,C[Si](C)(C)I,,test
US05026856,O=C(O)c1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O.c1ccc2c(c1)CNC2>>O=C(O)c1c(C2NCc3ccccc32)n(C2CC2)c2c(F)cc(F)cc2c1=O,,ClC(Cl)Cl,,CN(C)C=O,,test
US20090270394A1,COC(=O)c1cc(O)cc(O)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1cc(OS(=O)(=O)C(F)(F)F)cc(OS(=O)(=O)C(F)(F)F)c1,,CCOCC,ClCCl,c1ccncc1,,test
US20120015958A1,CS(=O)(=O)Cl.ClCCl.O=C([O-])c1cccc(CO)n1>>COC(=O)c1cccc(COS(C)(=O)=O)n1,,ClCCl,,CCN(CC)CC,,test
US20010034343A1,CC(C)(C)OC(=O)N1CCCN(c2nc3ccccc3[nH]2)CC1.COCCOCCBr>>COCCOCCn1c(N2CCCN(C(=O)OC(C)(C)C)CC2)nc2ccccc21,,O,,CN(C)C=O,[H-].[Na+],test
US20100159596A1,C#CCBr.Cc1nnc(Cl)c2cc(O)ccc12>>C#CCOc1ccc2c(C)nnc(Cl)c2c1,,Cc1ccccc1,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120142717A1,COC(=O)CCc1ccc(OC)nc1.COC=O.NC(N)=S>>COc1ccc(Cc2c[nH]c(=S)[nH]c2=O)cn1,,COCCOC,,[H-].[Na+],,test
US05733922,BrCc1ccccc1.CC1(C)NC(=S)NC1=S>>CC1(C)NC(SCc2ccccc2)=NC1=S,,CCO,,,,test
US20030232875A1,Clc1ccc(Cl)nn1.NCCO>>NCCOc1cccnn1,,Cc1ccccc1C,,[H-].[Na+],,test
US03996374,C.CCOC(=O)c1c2ccc(Cl)cc2c(-c2ccccc2)n1CCO.O=S(=O)(O)Cl>>CCOC(=O)c1c2ccc(Cl)cc2c(-c2ccccc2)n1CCOS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US06211376B1,Cc1ccc2cccc(O)c2n1.O=Cc1ccco1>>Oc1cccc2ccc(C=Cc3ccco3)nc12,,CC(C)=O,,,,test
US20050171130A1,CC#CCO.CC(C)C(O)C(C)C.Clc1cc(Cl)ncn1>>CC#CCOc1cc(OC(C(C)C)C(C)C)ncn1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US04317830,O=C(O)CCC(=O)O.c1cn(CC2CCCCCCC2)cn1>>O=C(O)CCC(=O)O.c1cn(CC2CCCCCCC2)cn1,,CCO,,,,test
US20090306066A1,Cc1nc(NNC(=O)[C@H](CC2CCCC2)CN(C=O)OCc2ccccc2)c(F)c(N2CCN(C)[C@H](C)C2)n1>>Cc1nc(NNC(=O)[C@H](CC2CCCC2)CN(O)C=O)c(F)c(N2CCN(C)[C@H](C)C2)n1,,CO,,,,test
US20100120761A1,Nc1cccc(Br)c1.O=C1CCOCC1>>Brc1cccc(NC2CCOCC2)c1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20010018438A1,COc1ccc(-c2cc(S(=O)(=O)C(F)(F)F)c(=O)n(C)c2-c2ccncc2)cc1.OB(O)c1ccccc1>>COc1ccc(-c2cc(-c3ccccc3)c(=O)n(C)c2-c2ccncc2)cc1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20150210715A1,ON=Cc1ccc(Oc2ccc(Cl)cc2)cc1>>NCc1ccc(Oc2ccc(Cl)cc2)cc1,[Zn],CC(=O)O,,,,test
US20060074084A1,CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc3[nH]c(C(=O)O)c(-c4cccc(F)c4)c3c2)cc1.CN(C)CCN>>CN(C)CCNC(=O)c1[nH]c2ccc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)cc2c1-c1cccc(F)c1,,CO,ClCCl,,,test
US20080085890A1,C1CCNCC1.Cc1ccc(S(=O)(=O)OCCN(C)c2ccc([N+](=O)[O-])cc2)cc1>>CN(CCN1CCCCC1)c1ccc([N+](=O)[O-])cc1,,Cc1ccccc1,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20100184739A1,CCOC(=O)c1c[nH]c2c(Br)ccc(C)c2c1=O>>CCOC(=O)c1c[nH]c2cccc(C)c2c1=O,[Pd],,,CC(=O)[O-].[Na+],,test
US20030229949A1,N=C(N)n1cccn1.NC1CCN(c2ccc([N+](=O)[O-])cc2)C1>>N=C(N)NC1CCN(c2ccc([N+](=O)[O-])cc2)C1,,CN(C)C=O,,Cl,,test
US20060046980A1,CCOP(=O)(COS(=O)(=O)c1ccc(C)cc1)OCC.Cc1cc(O)cc(C)c1Br>>CCOP(=O)(COc1cc(C)c(Br)c(C)c1)OCC,,CN(C)C=O,,O,[H-].[Na+],test
US20040192644A1,CC(C)(C)OC(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NCCCCC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NCCCCC(=O)O,[Pd],CO,,O,,test
US05646173,CC(O)CN.COc1ccc2c(c1)CC(CC(C)=O)C2=O>>COc1ccc2c(c1)Cc1cc(C)n(CC(C)O)c1-2,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,O,,test
US20060111402A1,COc1ccc(C(=O)CBr)c(OC)c1.FC(F)(F)Cc1nc2cc(Cl)c(Cl)cc2[nH]1>>COc1ccc(C(=O)Cn2c(CC(F)(F)F)nc3cc(Cl)c(Cl)cc32)c(OC)c1,,CN(C)C=O,,[H-].[Na+],,test
US20060004043A1,CC1CCCN1.CCN(CC)CC.COC(=O)CBr>>CCOC(=O)CN1CCCC1C,,C1CCOC1,,,,test
US20080125436A1,Cc1cccc(NN)c1.O=CC(=O)O>>Cc1cccc(NN=CC(=O)O)c1,,O,,CCO,Cl,test
US20140288088A1,Cc1cc2c(cc1C1CO1)COC2=O.N#Cc1ccc2cc(N3CCNCC3=O)ccc2c1>>Cc1cc2c(cc1C(O)CN1CCN(c3ccc4cc(C#N)ccc4c3)C(=O)C1)COC2=O,,CCO,,,,test
US20160002218A1,CC(=O)Nc1nc(-c2cc(C)cc(OC(F)(F)F)c2)c(CN2CCC[C@H]2C)s1>>Cc1cc(OC(F)(F)F)cc(-c2nc(N)sc2CN2CCC[C@H]2C)c1,,O,,CCO,[Na+].[OH-],test
US20070155839A1,COc1ccc(C(=O)c2ccc(Br)cc2)c(C)c1>>Cc1cc(O)ccc1C(=O)c1ccc(Br)cc1,,c1ccccc1,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20090137561A1,COc1cccc(C(C)(C)C2C(=O)OC(C)(C)OC2=O)c1>>COc1cccc(C(C)(C)CC(=O)O)c1,,O,,CN(C)C=O,,test
US04154835,Cc1ccc(C(Cl)=C(Cl)Cl)cn1.O=[Se]=O>>O=C(O)c1ccc(C(Cl)=C(Cl)Cl)cn1,,CCOC(C)=O,,C1COCCO1,,test
US20130079341A1,CN.Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1NC(=O)c1cc2ncc(Cl)nc2s1>>CNc1cnc2cc(C(=O)Nc3cc(NC(=O)c4cccc(C(C)(C)C#N)c4)ccc3C)sc2n1,,CCC(C)O,,CO,,test
US20070060567A1,COC(=O)c1ccc(N)cc1.O=C(O)c1ccc2c(c1)N(S(=O)(=O)c1ccccc1)CC2>>COC(=O)c1ccc(NC(=O)c2ccc3c(c2)N(S(=O)(=O)c2ccccc2)CC3)cc1,,CN(C)C=O,ClCCl,O=S(Cl)Cl,,test
US20130116245A1,O=C1NCCn2c3c(c(Br)c21)CCCC3.O=S(=O)(c1ccccc1)N(F)S(=O)(=O)c1ccccc1>>O=C1NCCn2c3c(c(F)c21)CCCC3,,C1CCOC1,,[Li]CCCC,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(-c2ccc(OCC(=O)N(C)OC)cc2)c2ccnn12.C[Mg]Br>>CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(-c2ccc(OCC(C)O)cc2)c2ccnn12,,C1CCOC1,,CCOC(C)=O,[Cl-].[NH4+],test
US06133485,C[C@H](O)[C@@]1(c2ccc(F)cc2F)CO1.c1nc[nH]n1>>C[C@H](O)[C@](O)(Cn1cncn1)c1ccc(F)cc1F,,CN(C)C=O,,[H-].[Na+],,test
US20090062279A1,Brc1nccc2ccccc12.COc1ccccc1B(O)O>>COc1ccccc1-c1nccc2ccccc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20080280877A1,Clc1cnc(Cl)cn1.O=C(c1ccccc1)N1CC(CO)(C(=O)O)C1>>O=C(c1ccccc1)N1CC(COc2cnc(Cl)cn2)(C(=O)O)C1,,CS(C)=O,O,[H-].[Na+],,test
US20020183375A1,Cc1cc(C)c(Nc2ccc(F)cc2[N+](=O)[O-])c(C)c1>>Cc1cc(C)c(Nc2ccc(F)cc2N)c(C)c1,[Pd],CCOC(C)=O,,,,test
US20150166564A1,CC1(C)OCC(COS(C)(=O)=O)CO1.Cc1c(N)n(-c2ccccc2)[nH]c1=O>>Cc1c(OCC2COC(C)(C)OC2)nn(-c2ccccc2)c1N,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050272709A1,CC#N.COC(=O)c1cccn1C>>Cn1cccc1C(=O)CC#N,,Cc1ccccc1,,CC(C)(C)[O-].[K+],,test
US20150368245A1,CN1CN([C@@H]2CC[C@@H](CO[Si](C)(C)C(C)(C)C)CC2)c2c(cnc3c2ccn3COCC[Si](C)(C)C)C1=O>>CN1CN([C@@H]2CC[C@@H](CO)CC2)c2c(cnc3c2ccn3COCC[Si](C)(C)C)C1=O,,C1COCCO1,,Cl,O=C([O-])O.[Na+],test
US20060293299A1,CO.COC(=O)C(c1cc(F)cc(F)c1)C1CN(C(c2ccccc2)c2ccccc2)C1.[Li]C>>CC(C)(O)[C@H](c1cc(F)cc(F)c1)C1CN(C(c2ccccc2)c2ccccc2)C1,,C1CCOC1,,CCOCC,,test
US20100305143A1,Cn1ccc2c(Cl)nc(Cl)nc21.O=C1CCC(=O)N1Br>>Cn1cc(Br)c2c(Cl)nc(Cl)nc21,,CN(C)C=O,,,,test
US20150166480A1,BrCc1ccccc1.CC(C)(C)OC(=O)N1CCC(CNc2ccc(Br)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(CN(Cc2ccccc2)c2ccc(Br)cc2)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US20150018343A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCC1CNCCO1>>CC(C)(C)OC(=O)N1CCOC(CO)C1,CN(C)c1ccncc1,ClCCl,,,,test
US20060205737A1,C1CNCCN1.COc1ccc(OC)c2c1CCCC2Nc1cc(F)ccc1S(C)(=O)=O>>COc1ccc(OC)c2c1CCCC2Nc1cc(N2CCNCC2)ccc1S(C)(=O)=O,,CC#N,,CCN(C(C)C)C(C)C,,test
US20030166650A1,C1COCCN1.CC(NC(=O)OC(C)(C)C)c1cccc(OS(=O)(=O)C(F)(F)F)c1>>CC(NC(=O)OC(C)(C)C)c1cccc(N2CCOCC2)c1,,ClCCl,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20120134934A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O.O[C@H]1CN2CCC1CC2>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O[C@H]1CN2CCC1CC2,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US07002047B2,O=C1CCCC(O)=C1O>>O=C1C=C[C@H](O)[C@@H](O)C1,,O=C(O)C(F)(F)F,,ClCCl,O,test
US20050080111A1,CCSc1cc(B2OC(C)(C)C(C)(C)O2)cc(C(F)(F)F)c1.N#Cc1c(C(F)(F)F)cc(-c2ccc(Br)o2)n(Cc2ccc(F)cc2F)c1=O>>CCSc1cc(-c2ccc(-c3cc(C(F)(F)F)c(C#N)c(=O)n3Cc3ccc(F)cc3F)o2)cc(C(F)(F)F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20140155391A1,COc1ccc(C(=O)O)cc1N(C(=O)OC(C)(C)C)S(=O)(=O)CCN1CCN(C)CC1.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>COc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1N(C(=O)OC(C)(C)C)S(=O)(=O)CCN1CCN(C)CC1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20030045560A1,CCCCc1c(C(=O)Cl)oc2ccccc12.CNCc1ccc2c(Br)c(OC)ccc2c1>>CCCCc1c(C(=O)N(C)Cc2ccc3c(Br)c(OC)ccc3c2)oc2ccccc12,,ClCCl,,CCN(CC)CC,,test
US20020193367A1,CC(C)(C)OC(=O)Nc1cc(Cl)c(Cl)cc1[N+](=O)[O-].CNC>>CN(C)c1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1Cl,,CS(C)=O,,,,test
US04131674,CCC(C)N.O=C(Oc1ccccc1)OC1c2ccccc2C(=O)N1c1ccc2ccc(Cl)nc2n1>>CCC(C)NC(=O)OC1c2ccccc2C(=O)N1c1ccc2ccc(Cl)nc2n1,,CC(C)OC(C)C,,,,test
US20130225567A1,CC(C(=O)Nc1ccc(B(O)O)c(C#C[Si](C(C)C)(C(C)C)C(C)C)n1)N(C)C(=O)OC(C)(C)C.Cc1ccn2c(I)c(-c3ccncc3)nc2c1>>Cc1ccn2c(-c3ccc(NC(=O)C(C)N(C)C(=O)OC(C)(C)C)nc3C#C[Si](C(C)C)(C(C)C)C(C)C)c(-c3ccncc3)nc2c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US05945535,CCOC(=O)C(Br)(CC)CC(C)C.CCOC(=O)C(C)(C)Br.CCOCC.COc1cccc(CC#N)c1.N#CCc1ccccc1>>CC(N)C(C)(C)C(=O)[O-].CCOC(=O)C(C)(C)C(C)N.CCOCC,[Zn],CCOCC,,,,test
US03950320,C=[N+]=[N-].CCC(C(=O)C(C)C(O)C(C)CCCC(=O)c1ccc(C)c(O)c1C(=O)O)C1OC(CC)(C2CCC(O)(CC)C(C)O2)CC1C>>CCC(C(=O)C(C)C(O)C(C)CCCC(=O)c1ccc(C)c(O)c1C(=O)OC)C1OC(CC)(C2CCC(O)(CC)C(C)O2)CC1C,,CCOCC,,Cl,[Na],test
US04220647,CCOC(CN(C(=O)OCc1ccccc1)c1ccc(F)cc1)OCC.Cl.NCCc1ccc(O)c(O)c1>>Cl.O=C(OCc1ccccc1)N(CC1NCCc2cc(O)c(O)cc21)c1ccc(F)cc1,,O,,CCCCO,,test
US20090275537A1,CN(C(=O)NCc1cccc(F)c1Cl)[C@@H](CCC(=O)N1CCN(C(=O)OC(C)(C)C)CC1)COC(=O)Nc1nc2ccccc2s1>>CN(C(=O)NCc1cccc(F)c1Cl)[C@@H](CCC(=O)N1CCNCC1)COC(=O)Nc1nc2ccccc2s1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030055047A1,Cc1cc(C(=O)Cl)ccc1Br.c1cnc2c(c1)NCc1cccn1C2>>Cc1cc(C(=O)N2Cc3cccn3Cc3ncccc32)ccc1Br,,ClCCl,,CCN(CC)CC,,test
US20080312226A1,Cc1noc(NC(=O)OCC(Cl)(Cl)Cl)c1C.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>Cc1noc(NC(=O)N2CCN(c3nc(-c4ccccc4)ns3)CC2)c1C,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20020019389A1,CCCNc1nc(NCCC)nc(N2CCNCC2)n1.O=C([O-])N(c1ccccc1)C(c1ccccc1)c1ccccc1>>CCCNc1nc(NCCC)nc(N2CCN(C(=O)NC(c3ccccc3)c3ccccc3)CC2)n1,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20130059834A1,CC(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(C)c4ccc(CO)cc34)nc12>>CC(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(C)c4ccc(C=O)cc34)nc12,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04471116,CC(C)Nc1cccc(Oc2ccc(OCc3ccccc3)cc2)c1>>CC(C)NCCCCCOc1ccc(O)cc1,[Pd],CC(=O)O,,[H][H],,test
US20090215776A1,Cc1cc(C=O)cc(B(O)O)c1.N>>Cc1cc(CN)cc(B(O)O)c1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140031349A1,CC(C)(C)OC(=O)N1CCC2(CC1)CCN(C1=CC(=O)OC1)C2=O>>O=C1C=C(N2CCC3(CCNCC3)C2=O)CO1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04595532,NC1CN(CC(=O)OC(c2ccccc2)c2ccccc2)C1=O.O=C(Cl)COc1ccccc1>>O=C(COc1ccccc1)NC1CN(CC(=O)OC(c2ccccc2)c2ccccc2)C1=O,,C1CCOC1,O,CCN(CC)CC,,test
US20140309225A1,CC(C)C(O)[C@H](C)NC(=O)OC(C)(C)C.O=C1NC(=O)c2ccccc21>>CC(C)[C@H]([C@H](C)NC(=O)OC(C)(C)C)N1C(=O)c2ccccc2C1=O,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140275004A1,COc1ccc(F)cc1-c1ncnc2c1ccn2S(=O)(=O)c1ccccc1.II>>COc1ccc(F)cc1-c1ncnc2c1cc(I)n2S(=O)(=O)c1ccccc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20080015203A1,CC(C)[Si](OC[C@H](C)Oc1cc(OCc2ccccc2)cc(C(=O)Nc2ccn(C)n2)c1)(C(C)C)C(C)C>>CC(C)[Si](OC[C@H](C)Oc1cc(O)cc(C(=O)Nc2ccn(C)n2)c1)(C(C)C)C(C)C,[Pd],C1CCOC1,,,,test
US20080306067A1,CN(C/C=C/CN)Cc1ccc(F)cc1.Cn1nnnc1-c1cccc(NC(=O)Oc2ccccc2)c1>>CN(C/C=C/CNC(=O)Nc1cccc(-c2nnnn2C)c1)Cc1ccc(F)cc1,,CS(C)=O,,,,test
US20100041693A1,COC(=O)C(=O)c1c[nH]c2ccccc12.Cc1cc2ccc(CN(C)C)cn2c1CC(N)=O>>Cc1cc2ccc(CN(C)C)cn2c1C1=C(c2c[nH]c3ccccc23)C(=O)NC1=O,,C1CCOC1,CCOC(C)=O,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US05308840,CN(C)c1cc(C2(C)OCCO2)ccc1O>>CC(=O)c1ccc(O)c(N(C)C)c1,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20140114068A1,O=C1c2ccccc2C(=O)C1(O)O.Oc1cccc2ccccc12>>O=C1c2ccccc2C2(O)Oc3c(ccc4ccccc34)C12O,,CC(=O)O,,,,test
US07608673B2,C=CCC(CC=C)CO[SiH2]c1ccc(I)cc1.COc1ccc(B(O)O)cc1>>C=CC[Si](O)(CC=C)c1ccc(-c2ccc(OC)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US03968121,CC(C)O.COc1ccc(-n2c(-c3ccccc3)cc3c2CCCC3)cc1>>Cc1cc(C)cc(C)c1,[Pd],,,,,test
US20160159752A1,CC(C)(C)OC(=O)N[C@H](C(=O)Nc1cccc(F)c1CC[C@H]1CN(C(=O)OC(C)(C)C)CC2(CC2)N1S(=O)(=O)c1ccccc1)C(c1ccc(F)cc1)c1ccc(F)cc1>>N[C@H](C(=O)Nc1cccc(F)c1CC[C@H]1CNCC2(CC2)N1S(=O)(=O)c1ccccc1)C(c1ccc(F)cc1)c1ccc(F)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020002152A1,CC(C)(C)OC(=O)N[C@H](CC1CCCCC1)C(O)C(=O)NN.O=Cc1ccc(Cl)cc1>>N[C@H](CC1CCCCC1)C(O)C(=O)N/N=C/c1ccc(Cl)cc1,,CCO,,c1ccncc1,,test
US20060178527A1,O=C(O)c1ccccc1F.OCc1ccccc1>>O=C(OCc1ccccc1)c1ccccc1F,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20090186879A1,CCOC(=O)CP(=O)(OCC)OCC.O=Cc1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl>>CCOC(=O)/C=C/c1ccc(Cl)c2nc3n(c12)CCCN3c1ccc(Cl)cc1Cl,,C1CCOC1,,O,[H-].[Na+],test
US20100249179A1,COC(=O)c1csc2cc(O)ccc12.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1csc2cc(OS(=O)(=O)C(F)(F)F)ccc12,,ClCCl,,c1ccncc1,,test
US20010027196A1,CS(=O)(=O)c1nc(N)nc(-c2ccco2)c1C#N.NCCCCc1ccccc1>>N#Cc1c(NCCCCc2ccccc2)nc(N)nc1-c1ccco1,,COCCOC,,,,test
US20130303492A1,C1CCNCC1.CCO.NC(=O)c1c(Nc2cccnc2)n[nH]c1N>>NC(=O)c1c(Nc2cccnc2)n[nH]c1N=Cc1ccc[nH]1,C1CCNCC1,,,,,test
US20070185161A1,CCC1(c2cn(C)c3c([N+](=O)[O-])cccc23)CCc2cc(F)ccc21>>CCC1(c2cn(C)c3c(N)cccc23)CCc2cc(F)ccc21,[Pd],CCO,,,,test
US20090221663A1,CCCSc1c(C(=O)NC2CCCCC2)cnn1-c1ccc(CC(=O)OC)cc1>>CCCSc1c(C(=O)NC2CCCCC2)cnn1-c1ccc(CC(=O)O)cc1,,CO,,[Na+].[OH-],,test
US20120157439A1,COC(=O)c1csc2c(Cl)ncnc12.COc1ccc(CN)c(OC)c1>>COC(=O)c1csc2c(NCc3ccc(OC)cc3OC)ncnc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20100121048A1,O=C(OC(=O)C(F)(F)F)C(F)(F)F.c1ccc(C[C@@H]2CNCCN2)cc1>>O=C(N1CCN(C(=O)C(F)(F)F)[C@H](Cc2ccccc2)C1)C(F)(F)F,,Cc1ccccc1,,,,test
US20030100770A1,O=C(OCc1ccccc1)[C@H]1CCCN1C(=O)CCc1cccc(CCC(=O)N2CCC[C@@H]2C(=O)OCc2ccccc2)n1>>O=C(O)[C@H]1CCCN1C(=O)CCc1cccc(CCC(=O)N2CCC[C@@H]2C(=O)O)n1,[Pd],CCO,,,,test
US20020090661A1,CC(N)Cc1ccc([N+](=O)[O-])cc1.NC(=O)C(F)(F)F>>CC(N)Cc1ccc(N)cc1.NC(=O)C(F)(F)F,[Pd],CCO,,,,test
US20020019569A1,CCOC(COCCCCO)OCC.CCc1cc(OC(=O)c2ccccc2)cc(CC)c1O>>CCOC(COCCCCOc1c(CC)cc(OC(=O)c2ccccc2)cc1CC)OCC,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100316601A1,COc1c(-c2cccc(C(=O)O)c2)cccc1[N+](=O)[O-]>>COc1c(N)cccc1-c1cccc(C(=O)O)c1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20080182854A1,CC(=O)Nc1ccc(C=C(C#N)C#N)cc1.CC(C)OC(C)C.CCO.NC(N)=S.O=C1CCC(=O)N1Br>>CC(=O)Nc1ccc(-c2nc(SCc3cccc(C)n3)nc(N)c2C#N)cc1,,CCO,,O=C([O-])O.[Na+],,test
US05660598,CCCCCC(C)Br.CCCCNc1ccccc1>>CCCCCC(C)N(CCCC)c1ccccc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100234387A1,CNC1CCc2cc(CN3CCCCC3)ccc2C1.COc1ccc2cc(S(=O)(=O)N3CCn4cccc4C3CC(=O)O)ccc2c1>>COc1ccc2cc(S(=O)(=O)N3CCn4cccc4C3CC(=O)N(C)C3CCc4cc(CN5CCCCC5)ccc4C3)ccc2c1,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020165245A1,Cc1ccc(S(=O)(=O)OC[C@H]2COc3ccc4nc(C)ccc4c3O2)cc1.Cc1ccc2[nH]cc(C3=CCNCC3)c2c1>>Cc1ccc2[nH]cc(C3=CCN(CC4COc5ccc6nc(C)ccc6c5O4)CC3)c2c1,,CS(C)=O,,,,test
US20110257151A1,C(=NC1CCCCC1)=NC1CCCCC1.ClCCl.O=Cc1cccc(C(=O)O)c1>>O=Cc1cccc(C(=O)OCc2ccccc2)c1,CN(C)c1ccncc1,ClCCl,,CCOC(C)=O,,test
US20050176775A1,BrC(Br)(Br)Br.O=C(OCC(Cl)(Cl)Cl)N1Cc2ccc(CO)cc2C1>>O=C(OCC(Cl)(Cl)Cl)N1Cc2ccc(CBr)cc2C1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20130204017A1,CCCCCCCC(=O)Cl.O=C1O[C@H]([C@@H](O)CO)C(O)=C1OCC(O)CO>>CCCCCCCC(=O)OC1=C(OCC(O)CO)C(=O)O[C@@H]1[C@@H](O)CO,,O,,CCN(CC)CC,CS(C)=O,test
US04800203,Cn1c2ccccc2c(=O)c2cccn21.O=C1CCC(=O)N1Cl>>Cn1c2ccccc2c(=O)c2ccc(Cl)n21,,C1CCOC1,,,,test
US20120088770A1,CCOC(OCC)[C@H](C)NCc1ccccc1.C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O>>CCOC(OCC)[C@H](C)N(Cc1ccccc1)C(=O)[C@H](C)NC(=O)OCC1c2ccccc2-c2ccccc21,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150183763A1,CC(C)(OCc1cccc(Cl)c1)C(F)(F)F.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(C)(OCc1cc(Cl)cc(B2OC(C)(C)C(C)(C)O2)c1)C(F)(F)F,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20020068747A1,CC(C)(C)OC(=O)NCC(=O)NCc1cc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)ccc1Br>>CC(C)(C)[Si](Oc1ccc(Br)c(CNC(=O)CN)c1)(c1ccccc1)c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100029619A1,COC(=O)C1(c2ccc(C(=O)Nc3cn4c(C)cccc4n3)cc2)CCC1>>Cc1cccc2nc(NC(=O)c3ccc(C4(C(=O)O)CCC4)cc3)cn12,,C1CCOC1,CCO,[K+].[OH-],,test
US20080108629A1,CCOC(=O)C(=O)Cl.NNC(=S)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1>>CCOC(=O)C(=O)NNC(=S)N1CCN(C(=O)c2ccccc2C(F)(F)F)CC1,,CN(C)C=O,,CCN(CC)CC,CCOC(C)=O,test
US04849414,CCCC[C@@H](CO)NS(=O)(=O)c1ccc(C)cc1.CCOP([O-])OCC>>CCCC[C@@H](CP(=O)(OCC)OCC)NS(=O)(=O)c1ccc(C)cc1,,C1CCOC1,,[H-].[Na+],,test
US20110224204A1,CC1(C)OB(c2ccc(OCc3ccc4ccccc4n3)cc2)OC1(C)C.N#Cc1ccc(OS(=O)(=O)C(F)(F)F)c(-c2ccncc2)c1>>N#Cc1ccc(-c2ccc(OCc3ccc4ccccc4n3)cc2)c(-c2ccncc2)c1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20160143895A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(C3=C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C3)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(C3C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C3)cc12,[Pd],CO,,,,test
US20060030609A1,NC1CCC1.O=C(O)Cc1cc([N+](=O)[O-])ccc1F>>O=C1Cc2cc([N+](=O)[O-])ccc2N1C1CCC1,,CS(C)=O,,,,test
US20090054407A1,CC(C)(C)OC(=O)n1c(-c2ccc(O)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21.O=S(=O)(Cl)c1cc2ccccc2s1>>CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)c3cc4ccccc4s3)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21,,CC#N,,CCN(CC)CC,,test
US20040162303A1,CC(=O)N1CCC(N)CC1.CCS(=O)c1ncc(C(=O)c2cc(C)ccc2OC)c(N)n1>>COc1ccc(C)cc1C(=O)c1cnc(NC2CCN(C(C)=O)CC2)nc1N,,CC(C)O,,,,test
US20090247547A1,CCOC(=O)Cc1c(CC)n[nH]c1CC>>CCc1n[nH]c(CC)c1CCO,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20030176454A1,NC(=S)Nc1cccc(-n2ccnc2)c1.O=C(CBr)c1ccccc1>>c1ccc(-c2csc(Nc3cccc(-n4ccnc4)c3)n2)cc1,,CCO,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US04254135,CCN1C[C@@H](O)[C@H](NC)C1.O=C(Cl)c1ccc(Cl)cc1>>CCN1C[C@@H](O)[C@H](N(C)C(=O)c2ccc(Cl)cc2)C1,,ClCCl,,O,O=C([O-])[O-].[K+].[K+],test
US20080171770A1,CO[C@@H](C)COc1ccc(C(C)NC(=O)OC(C)(C)C)cc1>>CO[C@@H](C)COc1ccc(C(C)N)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070275954A1,CC(C)(C)N(C(=O)O)C(C(=O)Nc1ncccc1C(=O)c1cccs1)c1ccc(F)cc1.O=C1Nc2ncccc2C(c2cccs2)=NC1c1ccc(F)cc1>>Fc1ccc(C2N=C(c3cccs3)c3cccnc3N=C2NC2CC2)cc1,,ClCCl,O,O=C(O)C(F)(F)F,,test
US20070135442A1,CI.O=C1NCCCN1c1ccc([N+](=O)[O-])cc1>>CN1CCCN(c2ccc([N+](=O)[O-])cc2)C1=O,,C1CCOC1,,[H-].[Na+],,test
US20080194633A1,COC(=O)C1(CO)CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)C1(CO)CCNCC1,,CO,,Cl,,test
US20130079321A1,CC(C)(C)OC(=O)N1CCC=CC(=O)C1.COc1ccc(CO)cc1>>COc1ccc(COC2CCN(C(=O)OC(C)(C)C)CC(=O)C2)cc1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20070225267A1,CN(C)C=O.Fc1cc(Br)cc(Br)c1.[Li]CCCC>>CCCCc1cc(F)cc(C=O)c1,,CCOCC,,,,test
US05455253,CC(=O)C=C(C)N.O=C1CCCC(=O)C1.O=Cc1cccc([N+](=O)[O-])c1>>CC(=O)C1=C(C)NC2=C(C(=O)CCC2)C1c1cccc([N+](=O)[O-])c1,,CCO,,,,test
US20140303121A1,Cc1noc(C)c1-c1cnc2c(-c3cnn(C)c3)c[nH]c2c1.N#C/C=C/C1CCCC1>>Cc1noc(C)c1-c1cnc2c(-c3cnn(C)c3)cn(C(CC#N)C3CCCC3)c2c1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110306625A1,Nc1c(Cl)cc(Br)c(Cl)c1Br>>Clc1cc(Br)c(Cl)c(Br)c1,,CCO,,CC(C)(C)ON=O,,test
US20120142717A1,COC(=O)/C(=C\O)Cn1ccc2ccccc21.NC(N)=S>>O=c1[nH]c(=S)[nH]cc1Cn1ccc2ccccc21,,CO,,,,test
US09085602B1,CC(C)CC(=O)O.C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3[C@H](O)CC4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C,[Pt],CO,,C[O-].[Na+],,test
US20110206607A1,COc1ccc(F)c(C=O)c1Cl>>O=Cc1c(F)ccc(O)c1Cl,,ClCCl,,BrB(Br)Br,,test
US20120028919A1,N#CC1(c2ccc([N+](=O)[O-])cc2)CCN(CC(N)=O)CC1>>N#CC1(c2ccc(N)cc2)CCN(CC(N)=O)CC1,[Pt],CO,ClCCl,,,test
US20100137313A1,COc1ncc(-c2cnc(Nc3ccc(F)c(Cl)c3)nc2S(C)(=O)=O)cn1.NCCc1c[nH]cn1>>COc1ncc(-c2cnc(Nc3ccc(F)c(Cl)c3)nc2NCCc2c[nH]cn2)cn1,,CN1CCCC1=O,,O,[H-].[Na+],test
US20080027070A1,Nc1ccc(Cl)c(C(=O)O)c1.O=C(Cl)c1cc(C(F)(F)F)ccc1F>>O=C(Nc1ccc(Cl)c(C(=O)O)c1)c1cc(C(F)(F)F)ccc1F,,C1CCOC1,,,,test
US20100105658A1,CCOC(=O)C1(CCCl)CCCN(Cc2ccccc2)CC1>>CCOC(=O)C12CCC[N+](Cc3ccccc3)(CC1)CC2.[Cl-],,CC#N,,,,test
US20110311461A1,NCc1ccccc1.O=CC(=O)O.OB(O)c1csc2ccccc12>>O=C(O)C(NCc1ccccc1)c1csc2ccccc12,,CC#N,,O,,test
US04908461,FC(F)(F)C(F)(F)C1(F)OC(F)(Cl)C(F)(Cl)O1>>FC1=C(F)OC(F)(C(F)(F)C(F)(F)F)O1,Cl[Ti](Cl)(Cl)Cl,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090221669A1,CC(C)(C)OC(=O)Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(N)cc1,[Pd],C1CCOC1,CCOC(C)=O,[H][H],,test
US20140275048A1,CC(C)(N)CCC(=O)OC(C)(C)C.O=CCCl>>CC(C)(CCC(=O)OC(C)(C)C)NCCCl,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20150119380A1,CC(=O)c1cccc(O)c1>>CC(O)c1cccc(O)c1,,CO,,Cl,[BH4-].[Na+],test
US20080081815A1,Cc1c(C(=O)Cl)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1.NC1CC1>>Cc1c(C(=O)NC2CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1,,ClCCl,,CCN(CC)CC,,test
US20110144105A1,COC(=O)c1cnc2c(c1)cc(C(=CC1CCCC1)c1ccc(SC)nc1)n2S(=O)(=O)c1ccccc1.O>>COC(=O)c1cnc2c(c1)cc(C(=CC1CCCC1)c1ccc(S(C)=O)nc1)n2S(=O)(=O)c1ccccc1,,CO,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20120309737A1,CC(C)(C)OC(=O)N1C2CNCC1C2.COCCOC(=O)Cl>>COCCOC(=O)N1CC2CC(C1)N2C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20060025474A1,CCC(CC)(c1ccc(CCC(O[Si](C)(C)C(C)(C)C)C(C)(C)C)c(C)c1)c1ccc(OS(=O)(=O)C(F)(F)F)c(C)c1>>CCC(CC)(c1ccc(CCC(O)C(C)(C)C)c(C)c1)c1ccc(OS(=O)(=O)C(F)(F)F)c(C)c1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20080051415A1,CC(C)(C)OC(=O)N1CCNC(CNc2cccnc2)C1.COc1ccc(N=C=O)cc1>>COc1ccc(NC(=O)N2CCN(C(=O)OC(C)(C)C)CC2CNc2cccnc2)cc1,,ClCCl,,,,test
US20060135491A1,CC(C)(O)CCCC1CCC2(CCCC(=O)C2)C1.C[Si](C)(C)n1ccnc1>>CC(C)(CCCC1CCC2(CCCC(=O)C2)C1)O[Si](C)(C)C,,C1CCOC1,,,,test
US06187802B1,BrBr.CC(=O)C(C)(C)c1ccc(Cl)c(Cl)c1>>CC(C)(C(=O)CBr)c1ccc(Cl)c(Cl)c1,,CCOCC,,,,test
US04963568,BrB(Br)Br.COc1ccc2c(c1OC)CC(c1ccccc1)C=C2CN>>Br.NCC1=CC(c2ccccc2)Cc2c1ccc(O)c2O,,ClCCl,,CO,Cl,test
US20020052512A1,COC(=O)[C@@H](N)CNC(=O)c1ccccc1.[N-]=[N+]=NCc1ccc(C(=O)ON2C(=O)CCC2=O)c(Cl)c1>>COC(=O)[C@H](CNC(=O)c1ccccc1)NC(=O)c1ccc(CN=[N+]=[N-])cc1Cl,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20160244429A1,N#Cc1ccc2[nH]cc(CC=O)c2c1.O=c1c(F)cc(F)cn1-c1ccc(N2CCNCC2)cc1>>N#Cc1ccc2[nH]cc(CCN3CCN(c4ccc(-n5cc(F)cc(F)c5=O)cc4)CC3)c2c1,,C1CCOC1,CO,CC(=O)O,[BH3-]C#N.[Na+],test
US20100063067A1,CC[Mg]Br.COc1cc(N2CCC(C(=O)N(C)OC)CC2)ccc1Cl>>CCC(=O)C1CCN(c2ccc(Cl)c(OC)c2)CC1,,C1CCOC1,CCOCC,Cl,,test
US20020169200A1,CC(C)(C)OC(=O)Cc1ccc2c(n1)N(C(=O)OC(C)(C)C)CCO2>>OCCc1ccc2c(n1)NCCO2,,C1CCOC1,,[BH4-].[Li+],,test
US20160263087A1,O=C1CCC(n2cc(-c3c[nH]c4cc(F)ccc34)cn2)CC1>>O[C@@H]1CC[C@H](n2cc(-c3c[nH]c4cc(F)ccc34)cn2)CC1,,CO,,[BH4-].[Na+],,test
US20140142083A1,C=O.COC(=O)c1cc(Br)cc(NC2CCOCC2)c1C>>COC(=O)c1cc(Br)cc(N(C)C2CCOCC2)c1C,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US06387896B1,CC(=O)OC(C)=O.CC(C)(C)C1Cc2ccccc2N1>>CC(=O)N1c2ccccc2CC1C(C)(C)C,CN(C)c1ccncc1,c1ccncc1,,O,,test
US20050192297A1,CCS.C[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CCSC(=O)[C@@H](C)NC(=O)OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20110152257A1,CC(C)(C)c1cc(N)[nH]n1.O=CC(Br)C=O>>CC(C)(C)c1cc2ncc(Br)cn2n1,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120065211A1,COC[C@H](C)Oc1nc(-c2ccc(Cl)nc2)nc2c1CNCC2.Cc1ccc(C(=O)O)cn1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COC[C@H](C)Oc1nc(-c2ccc(Cl)nc2)nc2c1CN(C(=O)Nc1ccc(C)nc1)CC2,,Cc1ccccc1,ClCCl,CCOCC,Cl,test
US20120316147A1,COC(=O)c1ccc(C2CC2)c(Nc2ccc(Cl)cc2Cl)n1>>O=C(O)c1ccc(C2CC2)c(Nc2ccc(Cl)cc2Cl)n1,,C1CCOC1,O,[Li+].[OH-],,test
US04425154,COc1cc(Cl)nc(N)n1.O=C=NS(=O)(=O)c1ccccc1OC(Cl)=CCl>>COc1cc(Cl)nc(NC(=O)NS(=O)(=O)c2ccccc2OC(Cl)=CCl)n1,,C1COCCO1,,,,test
US20080021032A1,CC(C)(C)[Si](C)(C)OCCn1ccc(N)n1.CS(=O)(=O)c1ccc([C@@H](C[C@H]2CCC(=O)C2)C(=O)Cl)cc1Cl>>CC(C)(C)[Si](C)(C)OCCn1ccc(NC(=O)[C@H](C[C@H]2CCC(=O)C2)c2ccc(S(C)(=O)=O)c(Cl)c2)n1,,ClCCl,,Cc1cccc(C)n1,,test
US20070105865A1,CN1Cc2cc(N)ccc2C(C)(C)C1.Clc1cccnc1-c1cnc2c(Cl)ncnc2c1>>CN1Cc2cc(Nc3ncnc4cc(-c5ncccc5Cl)cnc34)ccc2C(C)(C)C1.Cl,,CC(C)O,,,,test
US20110178041A1,COc1ccc(Br)c2cc(C(F)(F)F)nn12.NC=O>>Nc1ccc(Br)c2cc(C(F)(F)F)nn12,,CS(C)=O,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US20040162427A1,N#Cc1c(N)nc(Sc2ccccc2)c(C#N)c1-c1ccc2c(c1)OCCO2.NCc1ccccn1>>N#Cc1c(N)nc(NCc2ccccn2)c(C#N)c1-c1ccc2c(c1)OCCO2,,CN(C)C=O,,,,test
US20120149676A1,CC(C)(C)C(=O)Cl.NCc1ccc(Cl)c([N+](=O)[O-])c1Cl>>CC(C)(C)C(=O)NCc1ccc(Cl)c([N+](=O)[O-])c1Cl,,C1CCOC1,,,,test
US20110118257A1,O=c1c(-c2ccccc2)c(CN2CCOCC2)oc2ccc(Br)cc12>>O=c1c(-c2ccccc2)c(CN2CCOCC2)oc2ccccc12,[Pd],CO,,[H][H],,test
US20060241137A1,CC(=O)Cl.O=C(N1CCc2ccccc2C1)C(F)(F)F>>CC(=O)c1ccc2c(c1)CN(C(=O)C(F)(F)F)CC2,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20070049555A1,COC(=O)c1cccc(C#N)c1CBr.O=C1Cc2ccccc2C(=O)O1>>COC(=O)c1cccc2c1Cc1c-2[nH]c(=O)c2ccccc12,,CC#N,,CCN(CC)CC,,test
US20120083475A1,CC1(C)OC(=O)C2(CC2)C(=O)O1.CCc1ccc(N)cc1>>CCc1ccc(N2CCC(C(=O)O)C2=O)cc1,,CCO,,,,test
US20130172342A1,Cc1cccc(C)c1CCCBr.c1ccc2[nH]c(CN3CCCCC3)nc2c1>>Cc1cccc(C)c1CCCn1c(CN2CCCCC2)nc2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120172351A1,Cc1c(CO)cccc1-n1c([C@H]2CCCO2)nc2cc(OC(F)(F)F)ccc21>>Cc1c(C=O)cccc1-n1c([C@H]2CCCO2)nc2cc(OC(F)(F)F)ccc21,,CC#N,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20120149676A1,CC(C)(C)OC(=O)NCc1ccc(Cl)c(N=C=S)c1Cl.CNc1cc(N2CCC(C(F)(F)F)CC2)c(C(=O)NCCC(F)(F)F)cc1N>>Cn1c(Nc2c(Cl)ccc(CNC(=O)OC(C)(C)C)c2Cl)nc2cc(C(=O)NCCC(F)(F)F)c(N3CCC(C(F)(F)F)CC3)cc21,,CN(C)C=O,,CC(C)N=C=NC(C)C,,test
US20050192302A1,CC(C)[C@@H]1C[C@@H](OCc2ccccc2)CN1.O=C(O)CNC(=O)c1cccc(C(F)(F)F)c1>>CC(C)[C@@H]1C[C@@H](OCc2ccccc2)CN1C(=O)CNC(=O)c1cccc(C(F)(F)F)c1,,ClCCl,,ClCCCl,,test
US20020032340A1,CC(C)(O)CCBr.C[C@H](SC(=O)Oc1ccccc1)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>C[C@H](SCCC(C)(C)O)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,CO,[K+].[OH-],,test
US20160002204A1,CC(C)(C)OC(=O)Nc1cc[nH]c(=O)c1F.CCOC(=O)c1nnc(CCCCOS(C)(=O)=O)s1>>CCOC(=O)c1nnc(CCCCn2ccc(NC(=O)OC(C)(C)C)c(F)c2=O)s1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150344497A1,CC(C)(C)OC(=O)N1[C@@H](CCC=CC#N)COC1(C)C>>CC(C)(C)OC(=O)N[C@H](CO)CCC=CC#N,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20130085141A1,CC(C)(C)OC(=O)N1CCN2CC[C@@H](OC(=O)c3ccccc3)[C@@H]2C1>>CC(C)(C)OC(=O)N1CCN2CC[C@@H](O)[C@@H]2C1,,CO,,CC(C)(C)[O-].[K+],,test
US20110015178A1,CC1(C)CCCN(C(=O)c2csc(-c3cn[nH]c3)c2)CC1.OCCBr>>CC1(C)CCCN(C(=O)c2csc(-c3cnn(CCO)c3)c2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US03950339,CCCc1cc(Cl)nc(SCC#N)n1.NCc1ccc(Cl)cc1>>CCCc1cc(NCc2ccc(Cl)cc2)nc(SCC#N)n1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20120208817A1,CN(C)CCOc1cc(C=O)cc([N+](=O)[O-])c1O.NC(N)=O.O=C(Cc1ccccc1)c1ccccc1>>CN(C)CCOc1cc(C2NC(=O)NC(c3ccccc3)=C2c2ccccc2)cc([N+](=O)[O-])c1O,,CCO,,Cl,,test
US20070185171A1,Cn1c(C(F)(F)F)nc2cc([N+](=O)[O-])ccc21>>Cn1c(C(F)(F)F)nc2cc(N)ccc21,[Pd],CO,,,,test
US05554629,CCOP(=O)(CC(=O)OC)OCC.CN1CCC(=O)CC1>>COC(=O)CC1CCN(C)CC1,,C1CCOC1,,[H-].[Na+],,test
US20120184747A1,CCCCN(CC(F)(F)F)c1ccc(C(=O)OCC)cc1>>CCCCN(CC(F)(F)F)c1ccc(CO)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140099316A1,CCOC(=O)C1(COC)CCNCC1.ClCc1ccc(-c2noc(-c3ccc(C4CCCC4)c(Cl)c3)n2)cc1>>CCOC(=O)C1(COC)CCN(Cc2ccc(-c3noc(-c4ccc(C5CCCC5)c(Cl)c4)n3)cc2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120035346A1,BrC(C=Nc1ccccc1)=C[NH2+]c1ccccc1.O=C(O)CS.[Br-]>>O=C(O)CSC(C=Nc1ccccc1)=C[NH2+]c1ccccc1.[Br-],,CO,O,Cl,O=C([O-])O.[Na+],test
US20090118259A1,[N-]=[N+]=NCCn1cnc2cc(C(=O)N3CCCC4CCCCC43)ccc21>>NCCn1cnc2cc(C(=O)N3CCCC4CCCCC43)ccc21,[Pd],CO,,,,test
US20100331293A1,Cc1c(-c2ccccc2F)nc2ccccc2c1Cl.Nc1cc(Br)ccc1N1CCOCC1>>Cc1c(-c2ccccc2F)nc2ccccc2c1Nc1cc(Br)ccc1N1CCOCC1,,CN1CCCC1=O,,C1COCCO1,Cl,test
US20090264445A1,CC(C)(O)Cn1ccc(NC(=O)[C@H](CC2CCCCC2)N2CC(Oc3ccccc3Cl)=CC2=O)n1.COC(=O)C(N)C[C@@H]1C[C@@H](C)C1>>COC(=O)C(C[C@@H]1C[C@@H](C)C1)N1CC(Oc2ccccc2Cl)=CC1=O,,CC#N,,CCN(C(C)C)C(C)C,,test
US20010021714A1,CC(=O)O.CC(C)c1ccc(N)cc1.COC1CCC(OC)O1>>CC(C)c1ccc(-n2cccc2)cc1,,CC(=O)O,,,,test
US20120264735A1,COS(=O)(=O)OC.O=C(O)C1CCOC1>>COC(=O)C1CCOC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05652239,CCOC(=O)c1[nH]c2cccc(Br)c2c1C(=O)OCC.NN>>O=C1N=NC(=O)c2c1[nH]c1cccc(Br)c21,,CCO,,O,,test
US20050267095A1,BrCCBr.NCC1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1>>c1cc(C2(CN3CC3)CCOCC2)ccc1OCCCN1CCCC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110207750A1,COC(=O)c1ccc(F)c([N+](=O)[O-])c1.Nc1ccc(OC(F)(F)F)cc1>>COC(=O)c1ccc(Nc2ccc(OC(F)(F)F)cc2)c([N+](=O)[O-])c1,,CN(C)C=O,,CCN(CC)CC,,test
US20040106520A1,CN(C)C=C1CCC(C)(C)C1=O.NN>>CC1(C)CCc2c[nH]nc21,,CCO,,O,,test
US20070208007A1,CCCN(CCC)CCCCN(CC)Cc1ccc(CNC(=O)OC(C)(C)C)cc1>>CCCN(CCC)CCCCN(CC)Cc1ccc(CN)cc1,,CO,,C1COCCO1,Cl,test
US20020049222A1,C=C1CCC(C(=O)OC)C1.O=[O+][O-]>>COC(=O)C1CCC(=O)C1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US09272983B2,C=CC[C@@H](C)[C@H](C(=O)OC)N1C(=O)c2ccccc2C1=O>>C=CC[C@@H](C)[C@@H](N)C(=O)O,,CC(=O)O,Cl,,,test
US20120157435A1,CC(=O)OC(C)=O.CCc1ccccc1N>>CCc1ccccc1NC(C)=O,,O,,,,test
US20090018103A1,COCCCOS(C)(=O)=O.C[Si](C)(C)CCS(=O)(=O)N1CCCC(C(O)c2ccccc2Br)C1>>COCCCOC(c1ccccc1Br)C1CCCN(S(=O)(=O)CC[Si](C)(C)C)C1,,C1CCOC1,,[H][H],[H-].[Na+],test
US04657899,CCOC(=O)C(NC(C)=O)C(=O)OCC.CCOP(=O)(Cc1ccccc1CCBr)OCC>>CCOC(=O)C(CCc1ccccc1CP(=O)(OCC)OCC)(NC(C)=O)C(=O)OCC,,CCO,Cc1ccccc1,[Na],,test
US20050075346A1,CCN(C(C)C)C(C)C.COc1nc(Br)cnc1NS(=O)(=O)c1ccc(Cl)s1.C[Si](C)(C)CCOCCl>>CCCC(C)C.CCOC(C)=O,,ClCCl,,,,test
US20110053909A1,OCC#Cc1cccc(CO)c1>>OCCCc1cccc(CO)c1,[Pd],CCO,,,,test
US06143751,C[C@H](Oc1ccc(B(O)O)cc1)[C@@H](CCc1cccnc1)O[Si](C)(C)C(C)(C)C.NS(=O)(=O)c1cc(Br)cs1>>C[C@H](Oc1ccc(-c2csc(S(N)(=O)=O)c2)cc1)[C@H](O)CCc1cccnc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20070254940A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCCNC1CC=C(c2c[nH]c3cc([N+](=O)[O-])ccc23)CC1>>CCCN(C(=O)OC(C)(C)C)C1CC=C(c2c[nH]c3cc([N+](=O)[O-])ccc23)CC1,,C1COCCO1,,CCN(CC)CC,,test
US20120282218A1,COC(=O)C(O)=CC(=O)c1cc(Cc2ccc(F)cc2F)cn(Cc2ccccc2F)c1=O>>O=C(O)C(O)=CC(=O)c1cc(Cc2ccc(F)cc2F)cn(Cc2ccccc2F)c1=O,,C1COCCO1,,Cl,,test
US20030144288A1,C1CCOC1.CCN(C(C)C)C(C)C.CO.COc1ccc(C2=CCN(C(=O)OC(C)(C)C)CC2)c2sc(N)nc12>>COc1ccc(C2=CCN(C(=O)OC(C)(C)C)CC2)c2sc(NC(=O)c3ccnc(C)c3)nc12,,ClCCl,,,,test
US20090227548A1,CSc1cccc(S)c1.O=Cc1ccc(F)cc1>>CSc1cccc(Sc2ccc(C=O)cc2)c1,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US04220644,NC(=O)CCC(Sc1nnn[nH]1)C1=C(C(=O)O)N2C(=O)C(N)[C@H]2SC1.O=C(O)CSC(F)(F)F>>NC(=O)CCC(Sc1nnn[nH]1)C1=C(C(=O)O)N2C(=O)C(NC(=O)CSC(F)(F)F)[C@H]2SC1,,CCN(CC)CC,,CN(C)C=O,,test
US20060111445A1,CCCCCCc1cc2c(cc1OCCCC(=O)OCC)C(=O)CC2>>CCCCCCc1cc2c(cc1OCCCC(=O)O)C(=O)CC2,,O,,CCO,[K+].[OH-],test
US20010000345A1,Cc1c([N+](=O)[O-])ccc2c1ncn2C(=O)OC(C)(C)C>>Cc1c(N)ccc2c1ncn2C(=O)OC(C)(C)C,[Pd],CCOC(C)=O,CO,O=C[O-].[NH4+],,test
US20090105217A1,COC(=O)c1ccc(NC(=O)c2ccccc2F)cc1.NN>>NNC(=O)c1ccc(NC(=O)c2ccccc2F)cc1,,CO,,O,,test
US20080300275A1,CO.O=C(CCOCCc1ccccc1)N(CCNCCc1ccc(O)c2[nH]c(=O)sc12)Cc1ccccc1>>O=c1[nH]c2c(O)ccc(CCNCCN(CCCOCCc3ccccc3)CCc3ccccc3)c2s1,,C1CCOC1,,B,,test
US20160052930A1,Fc1cnc(Cl)nc1N1C[C@@H]2CC[C@H](C1)N2.O=C(O)C1CC1>>O=C(C1CC1)N1[C@H]2CC[C@@H]1CN(c1nc(Cl)ncc1F)C2,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040152690A1,FC(F)(F)c1cc(C2=CCC(C(F)(F)F)CC2)c2nc(N3CCN(c4ncccc4C(F)(F)F)CC3)[nH]c2c1>>FC(F)(F)c1cc(C2CCC(C(F)(F)F)CC2)c2nc(N3CCN(c4ncccc4C(F)(F)F)CC3)[nH]c2c1,[Pd],CCO,,[H][H],,test
US20090176778A1,CC(=O)Cl.O=C(c1nc2c(C(F)(F)F)cc(C3=CCNCC3)cn2c1Cl)N1CCC(c2cccc(F)c2)C1>>CC(=O)N1CC=C(c2cc(C(F)(F)F)c3nc(C(=O)N4CCC(c5cccc(F)c5)C4)c(Cl)n3c2)CC1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US05556864,CN1CCCC1CCCl.COCOc1cccc(CCc2ccccc2O)c1>>COCOc1cccc(CCc2ccccc2OCCC2CCCN2C)c1,,CC(=O)N(C)C,,Cl,CC(C)(C)[O-].[K+],test
US20100298558A1,CC(C)(C#N)N=NC(C)(C)C#N.Cc1ccc(C(=O)C=C(c2cc(Cl)cc(Cl)c2)C(F)(F)F)cc1Br.ClCCCl.O=C1CCC(=O)N1Br>>O=C(C=C(c1cc(Cl)cc(Cl)c1)C(F)(F)F)c1ccc(CN2C(=O)c3ccccc3C2=O)c(Br)c1,,ClC(Cl)Cl,,O,,test
US20110059118A1,CSc1ncc(-c2cnc3c(ccn3COCC[Si](C)(C)C)n2)c(N[C@H]2CCCN(S(C)(=O)=O)C2)n1>>C[Si](C)(C)CCOCn1ccc2nc(-c3cncnc3N[C@H]3CCCN(S(C)(=O)=O)C3)cnc21,[Ni],C1COCCO1,,CCO,O,test
US03979444,COC(=O)C1CC(C#N)(c2cccc3ccccc23)CCC1=O>>N#CC1(c2cccc3ccccc23)CCC(=O)CC1,,O,,CC(=O)O,O=S(=O)(O)O,test
US05942618,CCCCCCCCBr.CCCCCCCCC1CCc2cc(-c3ccc(O)cc3)nc(F)c2C1>>CCCCCCCCOc1ccc(-c2cc3c(c(F)n2)CC(CCCCCCCC)CC3)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20160046614A1,CCOC(=O)c1cccc(Sc2c(C3CC3)n(-c3cnn(CCNC(=O)OC(C)(C)C)c3)c3c(F)c(Cl)ccc23)c1F>>CCOC(=O)c1cccc(Sc2c(C3CC3)n(-c3cnn(CCN)c3)c3c(F)c(Cl)ccc23)c1F,,C1COCCO1,Cl,,,test
US20100298221A1,CC(C)(C)OC(=O)c1c(C(F)(F)F)cc(-c2cc(F)cc(F)c2)nc1Cl.Oc1ccc(Br)cc1F>>CC(C)(C)OC(=O)c1c(C(F)(F)F)cc(-c2cc(F)cc(F)c2)nc1Oc1ccc(Br)cc1F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150210647A1,O=C1CCC(=O)N1Cl.O=Cc1ccc2ccc(O[C@H]3CC[C@@H](C(F)(F)F)CC3)cc2c1>>O=Cc1ccc2ccc(O[C@H]3CC[C@@H](C(F)(F)F)CC3)c(Cl)c2c1,,CC#N,,O=C(O)C(F)(F)F,,test
US20050113379A1,CCc1cccc(N)n1.O=C1CCC(=O)N1Br>>CCc1nc(N)ccc1Br,,ClC(Cl)Cl,,,,test
US04536391,CS(=O)(=O)Cl.N#Cc1ccc(CCCO)cc1>>CS(=O)(=O)OCCCc1ccc(C#N)cc1,,ClCCl,,CCN(CC)CC,,test
US20070213341A1,CCOC(=O)N1C(=O)C2(c3ccc(Cl)cc31)C(c1cc(F)ccc1C)CC(=O)NC2c1cccc(Cl)c1>>Cc1ccc(F)cc1C1CC(=O)NC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12,,CO,,[Na+].[OH-],,test
US20140135330A1,COCCOc1ccc([C@@H]2OC(=O)N[C@H]2C(=O)OC)cc1>>COCCOc1ccc([C@@H]2OC(=O)N[C@H]2CO)cc1,,CCO,,Cl,[BH4-].[Na+],test
US05780633,COC(=O)CCCC(Br)C(=O)Cl.Oc1ccccc1>>COC(=O)CCCC(Br)C(=O)Oc1ccccc1,,CCOCC,,CCN(C(C)C)C(C)C,Cl,test
US20060106075A1,CC(=O)Cl.CCc1ccccc1CC>>CCc1ccc(C(C)=O)cc1CC,,C[N+](=O)[O-],,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20100256698A1,Cn1c(C(C)(C)C)c(-c2ccccc2)c2cc(O)ccc2c1=O.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>Cn1c(C(C)(C)C)c(-c2ccccc2)c2cc(OS(=O)(=O)C(F)(F)F)ccc2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030060466A1,CS(=O)(=O)c1nc(Cl)c(C#N)c(NCCO)n1.NCc1cccnc1>>N#Cc1c(Cl)nc(NCc2cccnc2)nc1NCCO,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20070197537A1,O=c1c(-c2ccc(OCc3ccccc3)c(F)c2)cnc2n1CCN2c1ccccc1>>O=c1c(-c2ccc(O)c(F)c2)cnc2n1CCN2c1ccccc1,,O=C(O)C(F)(F)F,,,,test
US20060178373A1,CC(C)N.COc1cc(-c2cc(=O)c3ccc(OCC4CO4)cc3o2)cc(OC)c1OC>>COc1cc(-c2cc(=O)c3ccc(OCC(O)CNC(C)C)cc3o2)cc(OC)c1OC,,CO,,,,test
US05292762,C#CCBr.O=c1[nH]nc(-c2ccccc2)s1>>C#CCn1nc(-c2ccccc2)sc1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130053366A1,C#Cn1c2c(c3cc(C)ccc31)CN(C)CC2.NS(=O)(=O)c1ccc(Br)s1>>Cc1ccc2c(c1)c1c(n2C#Cc2ccc(S(N)(=O)=O)s2)CCN(C)C1,,O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040082619A1,COc1nc(C)c(C)cc1[N+](=O)[O-]>>COc1nc(C)c(C)cc1N,[Pd],C1CCOC1,CO,,,test
US08101612B2,COC(=O)c1ccc(C)c(-c2ccc3c(-c4ccc(S(=O)(=O)C(F)(F)F)cc4C)nncc3c2)c1>>Cc1ccc(C(=O)O)cc1-c1ccc2c(-c3ccc(S(=O)(=O)C(F)(F)F)cc3C)nncc2c1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20040138230A1,CC1(C)CC(=O)Nc2ccc(C(=O)CCCl)cc21>>CC1(C)CC(=O)Nc2ccc(CCCCl)cc21,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20150336935A1,COc1cc(OC)cc(C(=O)[C@H]2[C@H](C)[C@@H](CN)C[C@H]3C(C)(C)CCC[C@]23C)c1.O=C(O)c1ccccc1>>COc1cc(OC)cc(C(=O)[C@H]2[C@H](C)[C@@H](CNC(=O)c3ccccc3)C[C@H]3C(C)(C)CCC[C@]23C)c1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20060281743A1,CC(=O)Cl.COc1ccc2c(=O)n(C)c(CCN)c(-c3ccccc3)c2c1>>COc1ccc2c(=O)n(C)c(CCNC(C)=O)c(-c3ccccc3)c2c1,,ClCCl,,CCN(CC)CC,Cl,test
US05025025,CCOC(=O)CS.Cc1ccc(S(=O)(=O)OC(CCCCOC2CCCCO2)CCCc2cccnc2)cc1>>CCOC(=O)CSC(CCCCOC1CCCCO1)CCCc1cccnc1,,C1CCOC1,CN(C)C=O,O,CC(C)(C)[O-].[K+],test
US20160272617A1,Cc1cc(C(=O)NC2CCC(N(C)C)CC2(C)C)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)cc1.Cl>>Cc1cc(C(=O)NC2CCC(N(C)C)CC2(C)C)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)cc1.Cl,,C1COCCO1,,,,test
US20040053966A1,CNC.COc1cc(C)nc2ccc(NC(C)=O)cc12>>Cc1cc(N(C)C)c2cc(N)ccc2n1,,CC(=O)O,,,,test
US20100056515A1,CCC(CC)c1ccc(OC)c2nc(Cl)n(C)c12.Cc1cc(Cl)cc(Cl)c1N>>CCC(CC)c1ccc(OC)c2nc(Nc3c(C)cc(Cl)cc3Cl)n(C)c12,,CN1CCCC1=O,,[H-].[Na+],,test
US20160229847A1,C[C@H](NS(=O)C(C)(C)C)c1cccc(Br)n1>>C[C@H](N)c1cccc(Br)n1,,Cl,,,,test
US20120316192A1,CCOC(=O)C#CC(=O)OCC.COc1ccc2[nH]cc(CCN)c2c1.Cc1ccc2occ(C=O)c(=O)c2c1>>CCOC(=O)C1=CC(C(=O)c2cc(C)ccc2O)=CN2CCc3c([nH]c4ccc(OC)cc34)C12C(=O)OCC,,Cc1ccccc1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20050240021A1,COc1cc(C(=O)CBr)ccc1-c1ccccn1.Nc1nccs1>>COc1cc(-c2cn3ccsc3n2)ccc1-c1ccccn1,,CCO,,,,test
US06130239,CC(=O)c1c[nH]c(/C=C2\C(=O)Nc3ccc(F)c(C#C[C@@H]4CCCN4)c32)c1.Cl>>CC(=O)c1c[nH]c(/C=C2\C(=O)Nc3ccc(F)c(C#C[C@@H]4CCCN4)c32)c1.Cl,,C1COCCO1,,,,test
US20050026964A1,CCOC(=O)c1cnc(Cl)cc1Cl.Nc1ccc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1F>>CCOC(=O)c1cnc(Cl)cc1Nc1ccc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1F,,CCO,,Cl,,test
US05733921,CCC(C)C(NC(=O)c1ccccc1C(=O)N(SSc1ccccc1)C(C(=O)O)C(C)CC)C(=O)O>>CCC(C)C(C(=O)O)n1sc2ccccc2c1=O,,ClCCl,,BrBr,,test
US20060074083A1,O=C(CBr)C12CC3CC(CC(C3)C1)C2.O=Cc1ccccc1O>>O=C(c1cc2ccccc2o1)C12CC3CC(CC(C3)C1)C2,,CCO,,[K+].[OH-],,test
US20090124656A1,CC1(C)CCN(CCBr)c2ccc(C(=O)c3ccccc3)cc21.CCOC(=O)C(Cc1ccc(O)cc1)OCC>>CCOC(=O)C(Cc1ccc(OCCN2CCC(C)(C)c3cc(C(=O)c4ccccc4)ccc32)cc1)OCC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120115811A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.CCn1nc(-c2ccncc2)cc1N>>CCn1nc(-c2ccncc2)cc1NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20120094997A1,COC(=O)c1ccc2ccn(CCCBr)c(=O)c2c1.COc1ccc(O)cc1>>COC(=O)c1ccc2ccn(CCCOc3ccc(OC)cc3)c(=O)c2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04426385,Cc1cc([N+](=O)[O-])cc(C)c1Cl.Oc1ccc(Cl)c2c1CCCC2>>Cc1cc([N+](=O)[O-])cc(C)c1Oc1ccc(Cl)c2c1CCCC2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05744466,CC(C)(C)O.CCN(CC)CC.Cc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>C=C[C@@H]1C[C@H]1NC(=O)OC(C)(C)C,,CCOCC,,,,test
US20050209291A1,Nc1ccc2sc(N)nc2c1.O=C(N=C=S)c1ccccc1>>Nc1nc2cc(NC(=S)NC(=O)c3ccccc3)ccc2s1,,C1CCOC1,,,,test
US20060217424A1,CN.N#Cc1ccc(Cl)cc1Oc1cccc2c1CCCC2=O.O=C(O)/C=C/C(=O)O>>CNC1CCCc2c(Oc3cc(Cl)ccc3C#N)cccc21.O=C(O)/C=C/C(=O)O,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US04871746,CCOC(=O)CC[C@H](NC(=O)c1ccc(CN(Cc2cnc3nc(NC(=O)C(C)(C)C)nc(O)c3c2)C(=O)C(F)(F)F)cc1)C(=O)OCC>>CCOC(=O)CC[C@H](NC(=O)c1ccc(CN(CC2CNc3nc(NC(=O)C(C)(C)C)nc(O)c3C2)C(=O)C(F)(F)F)cc1)C(=O)OCC,O=[Pt],CC(=O)O,,,,test
US04963563,CI.CS(=O)(=O)Nc1ccc2c(c1)CCN(C(=O)CCc1ccccc1)C2.Cl>>CN(c1ccc2c(c1)CCN(CCCc1ccccc1)C2)S(C)(=O)=O.Cl,,CN(C)C=O,,[H-].[Na+],,test
US20140179667A1,Cc1cc(C)c(CN2CCc3cnc(OC(C)C)c(Cl)c3C2=O)c(OCc2ccccc2)n1>>Cc1cc(C)c(CN2CCc3cnc(OC(C)C)c(Cl)c3C2=O)c(=O)[nH]1,,O=C(O)C(F)(F)F,,,,test
US06258829B1,CCOC(=O)c1cc2c(nc1C)C(O)CCCC2.CI>>CCOC(=O)c1cc2c(nc1C)C(OC)CCCC2,,C1CCOC1,,O,[H-].[Na+],test
US04988496,COC(=O)CCC1CN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC1CCC(=O)O,,CCO,,[Na+].[OH-],,test
US20090275617A1,CC(=O)O.CCOC(=O)C[N+](=O)[O-].CCOC([O-])[O-].Nc1cc(F)cc(F)c1>>CCOC(=O)c1cn(-c2cc(F)cc(F)c2)c(C)n1,,CCOC(C)=O,O,,,test
US20150175601A1,C=CC(=O)Nc1cccc(-c2cccc3cnc(Cl)nc23)c1.CN1CCN(c2cc(F)c(N)c(F)c2)CC1>>C=CC(=O)Nc1cccc(-c2cccc3cnc(Nc4c(F)cc(N5CCN(C)CC5)cc4F)nc23)c1,,CCCCO,,O=C(O)C(F)(F)F,,test
US20070082907A1,BrCc1ccccc1.Cc1cc(Oc2cccc(C(=O)O)c2)ccc1O>>Cc1cc(Oc2cccc(C(=O)OCc3ccccc3)c2)ccc1O,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050131014A1,CCOC(=O)c1cnc2c(C(F)(F)F)cccc2c1OS(=O)(=O)C(F)(F)F.OB(O)c1ccccc1>>CCOC(=O)c1cnc2c(C(F)(F)F)cccc2c1-c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20100279970A1,NC1(Cl)N=CN=C2C1=NCN2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O.NC1CCCCC1>>OC[C@H]1O[C@@H](n2cnc3c(NC4CCCCC4)ncnc32)[C@H](O)[C@@H]1O,,CCO,,,,test
US20130053366A1,COc1ccc(C(C)(O)Cn2c3c(c4cc(C)ccc42)CN(C)CC3)cn1>>Cc1ccc2c(c1)c1c(n2CC(C)(O)c2ccc(O)nc2)CCN(C)C1,,Cl,,,,test
US04017622,CCOC(=O)c1cn(CCCl)c2nc(N3CCN(C)CC3)ccc2c1=O>>C=Cn1cc(C(=O)O)c(=O)c2ccc(N3CCN(C)CC3)nc21,,CC(=O)O,,[Na+].[OH-],,test
US20090291950A1,COc1ccc2c(Cl)ncnc2c1OC1CCCC1.Nc1c(Cl)cccc1Cl>>COc1ccc2c(Nc3c(Cl)cccc3Cl)ncnc2c1OC1CCCC1,,CN(C)C=O,,[H-].[Na+],O=C([O-])[O-].[K+].[K+],test
US20090186912A1,COc1ccc(CN)cc1.CS(=O)(=O)Cl>>COc1ccc(CNS(C)(=O)=O)cc1,,ClCCl,,,,test
US20150025278A1,C=COC1CCCCC1.CC(=O)Oc1cc(O)c(Br)cc1Br>>CC(=O)Oc1cc(OC(C)OC2CCCCC2)c(Br)cc1Br,,Cc1ccccc1,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20060252768A1,O=C(O)c1sc2cc(F)ccc2c1C1CCN(C(=O)c2ccccc2)CC1>>O=C(c1ccccc1)N1CCC(c2csc3cc(F)ccc23)CC1,,c1ccc2ncccc2c1,,,,test
US05229413,C=O.CCOC(=O)c1cc2ccccc2[nH]1>>O=C(O)c1[nH]c2ccccc2c1CO,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20080063678A1,CO.N#Cc1cccc(F)c1F>>COc1cccc(F)c1C#N,,CO,,O,C[O-].[Na+],test
US04769378,CC#N.OC1(c2ccc(Cl)cc2)c2ccc(Cl)cc2-c2ncncc21>>CC(=O)NC1(c2ccc(Cl)cc2)c2ccc(Cl)cc2-c2ncncc21,,CS(=O)(=O)O,,O=C([O-])O.[K+],,test
US20090156600A1,CC(=O)CC(C)=O.CS(=O)(=O)c1ccc(CBr)cc1>>CC(=O)C(Cc1ccc(S(C)(=O)=O)cc1)C(C)=O,,CN(C)C=O,Cl,[H-].[Na+],,test
US20100105607A1,CCBr.OCCOc1ccccc1>>CCOCCOc1ccccc1,,C1CCOC1,,CCOC(C)=O,[H-].[Na+],test
US20050026973A1,CCOC(=O)C(C)(C)Oc1ccc(OCCCl)cc1.O=C(c1ccccc1)c1ccc2c(c1)S(=O)C=N2>>CCOC(=O)C(C)(C)Oc1ccc(OCCn2c(=O)sc3cc(C(=O)c4ccccc4)ccc32)cc1,,CN(C)C=O,O,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20110237573A1,Cc1cc(B(O)O)ccn1.O=C(Cc1ccc(Br)c(C(F)(F)F)c1)Nc1ccc(-c2ccccc2)cn1>>Cc1cc(-c2ccc(CC(=O)Nc3ccc(-c4ccccc4)cn3)cc2C(F)(F)F)ccn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20080214520A1,COc1cccc2c1CCNCC2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COc1cccc2c1CCN(C(=O)C(F)(F)F)CC2,,ClCCl,,CCN(CC)CC,Cl,test
US20100035883A1,CCOC(=O)c1cccc2c1C(=O)C(c1nccs1)C(c1ccc(F)cc1)N2.NN>>O=c1[nH]nc2c3c(cccc13)NC(c1ccc(F)cc1)C2c1nccs1,,CO,,O,,test
US20160168148A1,CCI.Cc1nnc2ccc3c(cc(-c4ccn[nH]4)n3Cc3cc(Cl)cc(CO[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)c3)n12>>CCn1ccc(-c2cc3c(ccc4nnc(C)n43)n2Cc2cc(Cl)cc(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)c2)n1,,CN(C)C=O,,[H-].[Na+],,test
US20050043334A1,C[C@@H](OC(C)(C)C)[C@@H]1COC(Nc2ccc3ncnc(Nc4ccc(OCc5nccs5)c(Cl)c4)c3c2)=N1>>C[C@@H](O)[C@@H]1COC(Nc2ccc3ncnc(Nc4ccc(OCc5nccs5)c(Cl)c4)c3c2)=N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110201663A1,CCOC(=O)Cc1cc(F)c(N2C(=O)c3c(c(OCC)c4ccccc4c3OCC)C2O)c(F)c1>>CCOC(=O)Cc1cc(F)c(N2Cc3c(c(OCC)c4ccccc4c3OCC)C2=O)c(F)c1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US20100261762A1,CCOP(C)(=O)OCC.CON(C)C(=O)[C@H]1CCN(C(=O)OC(C)(C)C)C1>>CCOP(=O)(CC(=O)C1CCN(C(=O)OC(C)(C)C)C1)OCC,,C1CCOC1,,O,[Li]CCCC,test
US20090054405A1,COCCOCCl.Oc1ccc(F)nc1I>>COCCOCOc1ccc(F)nc1I,,CO,,CCN(CC)CC,ClCCCl,test
US20100160303A1,Cc1c(Br)cccc1N1C(=O)C2CCCCC2C1=O>>Cc1c(Br)cccc1N1C(=O)C2CCCCC2C1O,,CO,,[BH4-].[Na+],,test
US20080207728A1,CNC(=O)c1ccc(B(O)O)cc1Cl.O=C(N[C@@H](CO)Cc1c[nH]c2ccccc12)c1cc(I)cc2c1OCC=C2>>CNC(=O)c1ccc(-c2cc3c(c(C(=O)N[C@@H](CO)Cc4c[nH]c5ccccc45)c2)OCC=C3)cc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US05985905,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1cc2cc(Cl)c(Cl)cc2[nH]1>>CCOC(=O)C=Cc1cc2cc(Cl)c(Cl)cc2[nH]1,,Cc1ccccc1,,,,test
US20070149508A1,C=Cc1cnc(Nc2ccc(S(=O)(=O)N3CCN(C(=O)OC(C)(C)C)CC3)c(N3CCN(C(=O)OC(C)(C)C)CC3)c2)nc1.O=C(O)C(F)(F)F>>C=Cc1cnc(Nc2ccc(S(=O)(=O)N3CCNCC3)c(N3CCNCC3)c2)nc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20040053908A1,CNC(=O)Nc1ccc(Oc2ccnc3cc(O)c(C#N)cc23)cc1Cl.Cc1ccc(S(=O)(=O)OC[C@H]2CO2)cc1>>CNC(=O)Nc1ccc(Oc2ccnc3cc(OC[C@H]4CO4)c(C#N)cc23)cc1Cl,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05883294,CN(C)C=O.COc1cc(C)c(Br)c(C)c1>>COc1cc(C)c(C=O)c(C)c1,,C1CCOC1,CCOCC,[Li]C(C)(C)C,,test
US20030044845A1,CCCCOc1cc(C)c([N+](=O)[O-])c(C)c1>>CCCCOc1cc(C)c(N)c(C)c1,[Pd],CO,,Cl,,test
US20100035985A1,C=CCc1c(F)c(F)c(CO)c(F)c1F.CC(C#N)=C[C@@H]1[C@@H](C(=O)O)C1(C)C>>C=CCc1c(F)c(F)c(COC(=O)[C@@H]2[C@@H](C=C(C)C#N)C2(C)C)c(F)c1F,CN(C)c1ccncc1,ClC(Cl)Cl,,CCN=C=NCCCN(C)C,Cl,test
US20030096826A1,CON(C)C(=O)C(CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccccc1O.OCCc1ccc2ccccc2n1>>CON(C)C(=O)[C@H](CC(=O)OC(C)(C)C)NS(=O)(=O)c1ccccc1OCCc1cccc2ncccc12,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100204196A1,CC(C)=CC(=O)Cl.COc1ccc(N)cc1>>COc1ccc(NC(=O)C=C(C)C)cc1,,CC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20060264460A1,Cn1ccnc1C=O.N#Cc1cnc2c(C(F)(F)F)cc(N)cc2c1Nc1ccc(F)c(Cl)c1>>Cn1ccnc1CNc1cc(C(F)(F)F)c2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1,,CCO,,[BH3-]C#N.[Na+],,test
US20130225640A1,C=O.CCCCCCCCOC(=O)CC#N>>C=C(C#N)C(=O)OCCCCCCCC,,Cc1ccccc1,,,,test
US20120302540A1,Cc1ccc(C2CN(C)C(=O)C23CCCN(C(=O)OC(C)(C)C)C3)cc1>>Cc1ccc(C2CN(C)C(=O)C23CCCNC3)cc1,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US05424460,CC1C(Cl)(Cl)CCC2OC21Cl>>Cc1c(O)cccc1Cl,,CN(C)C=O,,Cl,,test
US20060089398A1,COC(=O)CC(=O)C(C)C.ON=C(Cl)c1c(Cl)cccc1Cl>>COC(=O)c1c(-c2c(Cl)cccc2Cl)noc1C(C)C,,C1CCOC1,,C[O-].[Na+],,test
US20130059835A1,CC(C)(C)OC(=O)C(C)(C)Br.CCOc1c(C(C)n2nc(C)c3c(N)ncnc32)cc(Cl)c(C#N)c1C1CNC1>>CCOc1c(C(C)n2nc(C)c3c(N)ncnc32)cc(Cl)c(C#N)c1C1CN(C(C)(C)C(=O)OC(C)(C)C)C1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120059162A1,COC(=O)c1ccc(-c2cnc3c(SC)nccn23)cc1>>CSc1nccn2c(-c3ccc(C(=O)O)cc3)cnc12,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20050267149A1,CCCCCCCNCCc1ccccc1.COC(=O)c1ccccc1COc1ccc(CC(=O)O)cc1>>CCCCCCCN(CCc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2C(=O)OC)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20140094474A1,Cn1cc(-c2nc(C(=O)OCc3ccccc3)cn2C)cn1>>Cn1cc(-c2nc(C(=O)O)cn2C)cn1,[Pd],CCO,,,,test
US20080009492A1,Nc1cc([N+](=O)[O-])cnc1N.O=Cc1ccc(F)c(F)c1>>O=[N+]([O-])c1cnc2[nH]c(-c3ccc(F)c(F)c3)nc2c1,,O=[N+]([O-])c1ccccc1,,,,test
US20020165235A1,N#Cc1cc(-c2ccccc2)ccc1N.O=C(Cl)Cl.OCc1cc2cc(-c3ccccc3)ccc2o1>>NC(=O)OCc1cc2cc(-c3ccccc3)ccc2o1,,Cc1ccccc1,,CCN(CC)CC,c1ccncc1,test
US20120122842A1,CC(=O)Cl.CC(C)(C)OC(=O)N1CCC(Sc2ccc(N)cc2)CC1>>CC(=O)Nc1ccc(SC2CCN(C(=O)OC(C)(C)C)CC2)cc1,,ClCCl,O,CCN(CC)CC,,test
US08003783B2,COc1cc(C=O)cc(OC)c1OC.C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=O>>COc1cc(C=C2CC3C4CCc5cc(O)ccc5C4CCC3(C)C2=O)cc(OC)c1OC,,CCO,,CC(=O)O,[K+].[OH-],test
US20030176496A1,COC(=O)CCCCl.NCC1CCCO1.S=C=S>>COC(=O)CCCSC(=S)NCC1CCCO1,,CCO,,[Na+].[OH-],,test
US20030092749A1,CCCCON=O.Cc1cccc(CC(=O)c2ccc3c(c2)n(C)c(=O)n3C2CCCC2)c1>>Cc1cccc(C(=NO)C(=O)c2ccc3c(c2)n(C)c(=O)n3C2CCCC2)c1,,CCO,O,C,C[O-].[Na+],test
US06441237B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cccc(C)c1C(CN)CO>>Cc1cccc(C)c1C(CO)CNC(=O)OC(C)(C)C,,CCOC(C)=O,,CC(=O)O,,test
US20110021506A1,N#Cc1ccc(F)cc1C(F)(F)F.N[C@H]1CC[C@H](O)CC1>>N#Cc1ccc(N[C@@H]2CC[C@@H](O)CC2)cc1C(F)(F)F,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20020169314A1,COC(=O)[C@H](N)C(C)C.O=S(=O)(Cl)c1ccc2nc(Cl)sc2c1>>COC(=O)[C@H](NS(=O)(=O)c1ccc2nc(Cl)sc2c1)C(C)C,,ClCCl,,CCN(CC)CC,Cl,test
US20160244441A1,C1CNC1.Nc1cc(Cl)ccn1>>Nc1cc(N2CCC2)ccn1,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020183327A1,CC(=O)Cl.Nc1ccc(C(F)(F)F)cn1.O=Cc1ccco1.[C-]#[N+]C1CCCCC1>>CC(=O)N(c1c(-c2ccco2)nc2ccc(C(F)(F)F)cn12)C1CCCCC1,,[O-][Cl+3]([O-])([O-])O,,,,test
US05679696,BrCC1CCCC1.COc1ccc(C=O)cc1O>>COc1ccc(C=O)c(OC)c1C1CCCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160264575A1,CC(C)(C)OC(=O)CCCN1C(=O)[C@@H]2Cc3c(n(Cc4ccc(F)cc4)c4ccccc34)CN2C1=O>>O=C(O)CCCN1C(=O)[C@@H]2Cc3c(n(Cc4ccc(F)cc4)c4ccccc34)CN2C1=O,,C1COCCO1,,Cl,,test
US20030187026A1,N#CCc1c[nH]c2ccccc12.O=Cc1cncc(Br)c1>>N#C/C(=C\c1cncc(Br)c1)c1c[nH]c2ccccc12,,CCO,,C,C[O-].[Na+],test
US20150344468A1,COCn1c(=O)sc2cc(C(C)C(N)=O)ccc21.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COCn1c(=O)sc2cc(C(C)C(N)=S)ccc21,,C1CCOC1,,,,test
US04673672,CCCCCCCCCCCCCCCCCCOCC1(COCc2ccccc2)CCC(=O)O1>>CCCCCCCCCCCCCCCCCCOCC1(CO)CCC(=O)O1,[Pd],O,,CCO,[H][H],test
US20110224204A1,CC1(C)OB(c2ccc(OCc3ccc4ccccc4n3)cc2)OC1(C)C.Cc1cccc(Br)c1OC1CCCCO1>>Cc1cccc(-c2ccc(OCc3ccc4ccccc4n3)cc2)c1OC1CCCCO1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US06017926,CC(C)(C)OC(=O)Nc1ccc(N)cn1.CI>>CN(C(=O)OC(C)(C)C)c1ccc(N)cn1,,CN(C)C=O,,O,[H-].[Na+],test
US20080293687A1,CNCCOCc1cnc(-c2ccc(C(=O)Nc3ccccc3NC(=O)OC(C)(C)C)cc2)c(C#N)c1>>CNCCOCc1cnc(-c2ccc(C(=O)Nc3ccccc3N)cc2)c(C#N)c1,,C1COCCO1,,Cl,,test
US20130310380A1,Cc1cc(B2OC(C)(C)C(C)(C)O2)ccn1.Cc1occc1-c1cc(N2C[C@H](C)O[C@H](C)C2)ccc1Br>>Cc1cc(-c2ccc(N3C[C@H](C)O[C@H](C)C3)cc2-c2ccoc2C)ccn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20120172377A1,CCOC(=O)CC(Cn1c2c(c3cc(C)ccc31)CN(C)CC2)c1ccc(F)cc1>>Cc1ccc2c(c1)c1c(n2CC(CC(=O)O)c2ccc(F)cc2)CCN(C)C1,,CO,,Cl,[Na+].[OH-],test
US20140371199A1,N#Cc1ccc(N)cc1.O=[N+]([O-])c1cnc(Br)cc1Br>>N#Cc1ccc(Nc2cc(Br)ncc2[N+](=O)[O-])cc1,,CCO,,CCN(CC)CC,,test
US20100009973A1,COC(=O)c1ccc([O-])cc1.N#Cc1c(-c2ccoc2)cc(-c2cccs2)nc1Br>>COC(=O)c1ccc(Oc2nc(-c3cccs3)cc(-c3ccoc3)c2C#N)cc1,,CN(C)C=O,Cl,[Na],,test
US20070161627A1,COc1ccc2nccc(CCC3(O)CCN(N)CC3)c2n1.O=C1CSc2ccc(C(=O)O)nc2N1>>COc1ccc2nccc(CCC3(O)CCN(NC(=O)c4ccc5c(n4)NC(=O)CS5)CC3)c2n1,,CN(C)C=O,ClCCl,ClCCCl,On1nnc2ccccc21,test
US04808729,COC(=O)CCCC(C)=O.SCC(S)CS>>COC(=O)CCCC1(C)SCC(CS)S1,,ClCCl,,CCOCC,FB(F)F,test
US20120077828A1,CC1(C)OB(c2ccc3c(c2)CCN3C(=O)Cc2cccc(C(F)(F)F)c2)OC1(C)C.CN(C)CCn1cc(Br)c2c(N)ncnc21>>CN(C)CCn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(C(F)(F)F)c2)c2c(N)ncnc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])O.[Na+],test
US20120289710A1,CN1CCCN(C)C1=O.COC(=O)c1ccccc1.COc1ccc(CN2C(=O)CC[C@H]2Cc2ccc(-c3ccccc3)cc2)cc1>>O=C(c1ccccc1)[C@H]1CC(Cc2ccc(-c3ccccc3)cc2)N(CN2CCCC2)C1=O,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],[Cl-].[NH4+],test
US20120232056A1,COC(=O)c1ccc2nc(-c3coc4ccccc34)c(N(C)C(C)C)nc2c1>>CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1coc2ccccc12,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20160151375A1,CC1(C)CCCC(=O)C1>>CC1(C)CCCC(O)C1,,CO,,[BH4-].[Na+],,test
US20150045339A1,CCCNc1nc(Nc2cccc(F)c2)ncc1C(=O)OCC>>CCCNc1nc(Nc2cccc(F)c2)ncc1CO,,C1CCOC1,,CCOC(C)=O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US04463002,CC(C)C(=O)OCI.CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=CCS[C@H]12)c1csc(N)n1>>CON=C(C(=O)NC1C(=O)N2C(C(=O)OCOC(=O)C(C)C)=CCS[C@H]12)c1csc(N)n1,,CCN(CC)CC,,,,test
US20110263549A1,CC(C)(C)OC(=O)[O-].OCCc1cn[nH]c1>>CC(C)(C)OC(=O)n1cc(CCO)cn1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20060258860A1,COC(=O)[C@@H]1CC(F)(F)CN1C(=O)OCc1ccccc1>>O=C(O)[C@@H]1CC(F)(F)CN1C(=O)OCc1ccccc1,,CO,,[Na+].[OH-],,test
US20130034616A1,CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc(-c3cnc4c(n3)c(N3Cc5cccc(Cl)c5C3=O)cn4C(c3ccccc3)(c3ccccc3)c3ccccc3)cc2)CC1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C1c2c(Cl)cccc2CN1c1c[nH]c2ncc(-c3ccc(S(=O)(=O)C4CCNCC4)cc3)nc12,,ClCCl,,CC[SiH](CC)CC,,test
US20070225288A1,CCOC(=O)C1=C(c2ccccc2)c2ccc(OC)cc2C1=O.Cl[Mg]C1CCCCC1>>CCOC(=O)C1=C(c2ccccc2)c2ccc(OC)cc2C1(O)C1CCCCC1,,C1CCOC1,,,,test
US20160031838A1,C[Si](C)(C)Cl.NC[C@@H](O)c1cccc2c1OCC(=O)N2>>C[Si](C)(C)O[C@H](CN)c1cccc2c1OCC(=O)N2,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05808062,CC(C)(C)N=C=O.O=c1oc(-c2ccccc2)cc(O)c1NCc1ccccc1>>CC(C)(C)NC(=O)N(Cc1ccccc1)c1c(O)cc(-c2ccccc2)oc1=O,,CCOC(C)=O,,CN1CCOCC1,Cl,test
US20090233900A1,NC1CC2CCC1C2.O=C(O)c1cccnc1Cl>>O=C(O)c1cccnc1N[C@@H]1C[C@H]2CC[C@@H]1C2,,[Na+],[OH-],,,test
US20140066369A1,O=C(Oc1c(F)c(F)c(F)c(F)c1F)Oc1c(F)c(F)c(F)c(F)c1F.OC1(C(F)(F)F)COC1>>O=C(Oc1c(F)c(F)c(F)c(F)c1F)OC1(C(F)(F)F)COC1,,C1CCOC1,,CC#N,CCN(CC)CC,test
US20100184998A1,C=CC=O.CCOC(=O)CC(C)C>>C=CC(O)C(C(=O)OCC)C(C)C,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20150072980A1,COc1cc2c(cc1Cl)C/C(=C\c1ccc(SC(F)(F)F)cc1)C2=O>>COc1cc2c(cc1Cl)CC(Cc1ccc(SC(F)(F)F)cc1)C2=O,[Pt],CO,,,,test
US20100160286A1,Cc1ccc(S(=O)(=O)O[C@@H]2CCOC2)cc1.Cn1ccc(NC(=O)c2cc(O)cc(Oc3ccc(C(=O)N4CCC4)cc3)c2)n1>>Cn1ccc(NC(=O)c2cc(Oc3ccc(C(=O)N4CCC4)cc3)cc(O[C@H]3CCOC3)c2)n1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20160272645A1,CC(C)(C)OC(=O)NCCn1cc(Br)c2c(N)ncnc21.OB(O)c1ccc(Cl)c(O)c1>>CC(C)(C)OC(=O)NCCn1cc(-c2ccc(Cl)c(O)c2)c2c(N)ncnc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20120328569A1,CC(C)(C)OC(=O)n1c(-c2ccnc(Cl)c2)cc2ccccc21>>Clc1cc(-c2cc3ccccc3[nH]2)ccn1,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20090233965A1,CI.CN1CCC(OC(=O)C(C)(c2ccccc2)C2CC2)CC1>>CC(C(=O)OC1CC[N+](C)(C)CC1)(c1ccccc1)C1CC1.[I-],,CC#N,ClCCl,,,test
US05576335,C(=NC1CCCCC1)=NC1CCCCC1.CC(C)(C)c1cc(C(=O)O)cc(C(C)(C)C)c1O.Nc1cc(Cl)c(Cl)cc1NC(=O)NC1CCCC1>>CCCCCCCNC(=O)Nc1cc(Cl)c(Cl)cc1NC(=O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1,,ClCCl,,,,test
US20060247292A1,CC(C)(CC(=O)C(=O)O)Cc1ccccc1Br.CI>>COC(=O)C(=O)CC(C)(C)Cc1ccccc1Br,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06211359B1,COCCCl.O=[N+]([O-])c1ccccc1O>>COCCOc1ccccc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04218448,C=C1CC(=O)O1.OC(c1ccc2c(c1)CCN2)(C(F)(F)F)C(F)(F)F>>CC(=O)CC(=O)N1CCc2cc(C(O)(C(F)(F)F)C(F)(F)F)ccc21,,C1CCOC1,,,,test
US06372764B1,Fc1ccc(C2C=CNCC2)cc1>>Fc1ccc(C2CCNCC2)cc1,[Pd],CO,,Cl,,test
US20060194763A1,COCC#CC(C)(C)NC(=O)C(Br)COC.Oc1cc(Cl)cc(Cl)c1>>COCC#CC(C)(C)NC(=O)C(COC)c1cc(Cl)cc(Cl)c1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20150320702A1,NCc1ccc(Cl)c(Cl)c1.O=C1C=C(Br)C(=O)c2ccccc21>>O=C1C=C(NCc2ccc(Cl)c(Cl)c2)C(=O)c2ccccc21,,CCO,,,,test
US20110312936A1,C=CCC(NS(=O)C(C)(C)C)C1CCC2(CC1)OCCO2>>C=CCC(N)C1CCC(OC)(OC)CC1,,CO,,Cl,,test
US20130071327A1,CC(C)(C)OC(=O)CCC[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C.N#Cc1ccc(CBr)cc1F>>N#Cc1ccc(CC(CC[C@H](N)C(=O)O)C(=O)O)cc1F,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04677100,O=C(CO/N=C(\C(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CCl)CS[C@H]12)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1)OC(c1ccccc1)c1ccccc1.O=C(OO)c1cccc(Cl)c1>>O=C(CO/N=C(\C(=O)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CCl)CS(=O)[C@H]12)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1)OC(c1ccccc1)c1ccccc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US06248739B1,O=C(NCc1ccc(Cl)cc1)c1cn(CSc2ccccc2)c2ccc(CN3CCOCC3)cc2c1=O.O=C(OO)c1cccc(Cl)c1>>O=C(NCc1ccc(Cl)cc1)c1cn(CS(=O)c2ccccc2)c2ccc(CN3CCOCC3)cc2c1=O,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20120101100A1,CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2cncc(C(=O)OCC)c2)cn1>>CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2cncc(C(=O)O)c2)cn1,,C1CCOC1,CO,[Li+].[OH-],,test
US06002008,N#Cc1cnc2ccc([N+](=O)[O-])cc2c1Nc1cccc(Cl)c1>>N#Cc1cnc2ccc(N)cc2c1Nc1cccc(Cl)c1,,CCO,,,,test
US20150203492A1,C=CC[C@H](NC(=O)OC(C)(C)C)c1cc(Cl)ccn1.CC(C)(C)OC(=O)Nc1cnccc1B(O)O>>C=CC[C@H](NC(=O)OC(C)(C)C)c1cc(-c2ccncc2NC(=O)OC(C)(C)C)ccn1,,C1CCOC1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20100298324A1,COc1cnc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)nc1OC.NCc1ccc(Cl)cc1>>COc1cnc(-n2c(=S)[nH]c3cc(C(=O)NCc4ccc(Cl)cc4)ccc3c2=O)nc1OC,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150011508A1,Cc1nc(-c2ccc(C)c(NC(=O)c3cnc4ccc(B(O)O)cn34)c2)no1.Cc1nc(CO)sc1Br>>Cc1nc(-c2ccc(C)c(NC(=O)c3cnc4ccc(-c5sc(CO)nc5C)cn34)c2)no1,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100125062A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1CCCCC1c1cccnc1F>>CC(=O)N1CCCCC1c1cccnc1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160002177A1,C[Si](C)(C)CCOCOc1cc(C2=Cc3ccccc3CC2)cc2c(=O)n(COCC[Si](C)(C)C)cnc12>>O=c1[nH]cnc2c(O)cc(C3=Cc4ccccc4CC3)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120053216A1,CO[C@H]1[C@H](ONCc2ccc(-c3ncn(-c4ccc(OC(F)(F)F)cc4)n3)cc2)O[C@@H](C)[C@H](OC)[C@H]1OC.O=C1CCC(=O)O1>>CO[C@H]1[C@H](ON(Cc2ccc(-c3ncn(-c4ccc(OC(F)(F)F)cc4)n3)cc2)C(=O)CCC(=O)O)O[C@@H](C)[C@H](OC)[C@H]1OC,,CCOC(C)=O,c1ccncc1,,,test
US20100298324A1,COc1cnc(-n2c(=S)[nH]c3cc(C(=O)O)ccc3c2=O)c(OC)c1.NCc1cccc(Cl)c1>>COc1cnc(-n2c(=S)[nH]c3cc(C(=O)NCc4cccc(Cl)c4)ccc3c2=O)c(OC)c1,,CC#N,CCOC(C)=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20120232068A1,CC1(C)OCC(c2cncc(B3OC(C)(C)C(C)(C)O3)c2)CO1.Clc1nc(NCc2ccccn2)c2c(-c3ccccc3)cccc2n1>>CC1(C)OCC(c2cncc(-c3nc(NCc4ccccn4)c4c(-c5ccccc5)cccc4n3)c2)CO1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20110237791A1,CC(=O)N(C)C.COc1nc(Br)ccc1I>>COc1nc(Br)ccc1C(C)=O,,CCOC(C)=O,CCOCC,O,[Li]CCCC,test
US20090247517A1,Nc1ccc(Cl)cc1.O=C(O)c1ccc(-c2ccnc(O)n2)cc1.O=P(Cl)(Cl)Cl>>O=C(Nc1ccc(Cl)cc1)c1ccc(-c2ccnc(Cl)n2)cc1,,O,,CCN(CC)CC,,test
US03954860,CCCC=O.NC(=O)Nc1ccc(Cl)cc1.c1ccc(OP(c2ccccc2)c2ccccc2)cc1>>CCCC(NC(=O)Nc1ccc(Cl)cc1)P(=O)(c1ccccc1)c1ccccc1,,Cc1ccccc1,,,,test
US06743811B2,CC(C)(C)OC(=O)c1ccc(N2CO[C@H](CN=[N+]=[N-])C2)cc1F.O=C(O)C(F)(F)F>>[N-]=[N+]=NC[C@@H]1CN(c2ccc(C(=O)O)c(F)c2)C(=O)O1,,ClCCl,,,,test
US20100152187A1,Nc1nc(Cc2ccccc2)c(C(=O)NCc2ccccc2)s1.O=C(Cl)CCc1ccccc1>>O=C(CCc1ccccc1)Nc1nc(Cc2ccccc2)c(C(=O)NCc2ccccc2)s1,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20100130497A1,C#CCOc1cc(C=O)ccc1OC.O=C(O)CC(=O)Nc1ccccc1C(=O)O>>C#CCOc1ccc(/C=C/C(=O)Nc2ccccc2C(=O)O)cc1OC,,Cc1ccccc1,,C1CCNCC1,CC(=O)O,test
US06423840B1,O=C(CCc1ccccc1)NC1CCC(=O)N2CCCC(C(=O)NC3CC(=O)OC3OCc3ccccc3)N2C1=O>>O=CC(CC(=O)O)NC(=O)C1CCCN2C(=O)CCC(NC(=O)CCc3ccccc3)C(=O)N12,[Pd],CO,,,,test
US20040132994A1,CC(C)(C)OC(=O)NCCCN.CCOc1c(Nc2cnn(C)c2NC(c2ccccc2)(c2ccccc2)c2ccccc2)c(=O)c1=O>>Cn1ncc(Nc2c(NCCCNC(=O)OC(C)(C)C)c(=O)c2=O)c1NC(c1ccccc1)(c1ccccc1)c1ccccc1,,CCCCCC,CCO,CCN(CC)CC,CCOCC,test
US20150005275A1,CC(=O)Cl.O=C(O)C1(O)CC1>>CC(=O)OC1(C(=O)O)CC1,,ClCCl,,c1ccncc1,,test
US20150291563A1,CSc1cccc(-c2ccc(C3CC(C(O)(C(F)(F)F)C(F)(F)F)=NN3c3ccccc3Cl)c(F)c2)c1.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1cccc(-c2ccc(C3CC(C(O)(C(F)(F)F)C(F)(F)F)=NN3c3ccccc3Cl)c(F)c2)c1,,ClCCl,,,,test
US20090062258A1,Nc1ccncn1.O=C(O)c1scc2[nH]c(=O)n(-c3cccc(S(=O)(=O)N4CCCc5ccccc54)c3)c(=O)c12>>O=C(Nc1ccncn1)c1scc2[nH]c(=O)n(-c3cccc(S(=O)(=O)N4CCCc5ccccc54)c3)c(=O)c12,CN(C)c1ccncc1,CN(C)C=O,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US05182289,CC1C(=O)N(c2ccccc2)c2ncccc21.Cc1ccc(S(=O)(=O)N(F)CC(C)(C)C)cc1>>CC1(F)C(=O)N(c2ccccc2)c2ncccc21,,C1CCOC1,ClCCl,Cl,[H-].[Na+],test
US20160009710A1,Clc1cc(OCC23CC4CC(CC(C4)C2)C3)c(Br)cn1.NN>>NNc1cc(OCC23CC4CC(CC(C4)C2)C3)c(Br)cn1,,C1COCCO1,,O,,test
US20090124596A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@H](NC(=O)c2cc(F)cnc2Nc2cccc(I)c2)CC1.O=C(n1ccnc1)n1ccnc1>>CC(C)(C)OC(=O)N[C@@H]1CC[C@H](n2c(=O)c3cc(F)cnc3n(-c3cccc(I)c3)c2=O)CC1,,CN1CCCC1=O,,O,[H-].[Na+],test
US20130059835A1,COc1c(C(C)Cl)cc(Cl)c(C)c1-c1ccc(C(=O)N(C)C)nc1.Nc1ncnc2[nH]cc(I)c(=O)c12>>COc1c(C(C)n2cc(I)c(=O)c3c(N)ncnc32)cc(Cl)c(C)c1-c1ccc(C(=O)N(C)C)nc1,,CN(C)C=O,CO,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US20100093748A1,Clc1ncnc2[nH]ccc12.N#CC1(c2nc3cc(Br)ccc3[nH]2)CCNCC1>>N#CC1(c2nc3cc(Br)ccc3[nH]2)CCN(c2ncnc3[nH]ccc23)CC1,,CN1CCCC1=O,,CCN(CC)CC,,test
US20160248017A1,CCCCC(CC)CBr.c1ccc2c(c1)[nH]c1ccccc12>>CCCCC(CC)Cn1c2ccccc2c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20130023502A1,CC1(C)CC2COC(C)(C)N2C1=O>>CC1(C)C[C@@H](CO)NC1=O,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120015976A1,Nc1ccc2[nH]c(=O)oc2c1.O=C(Cc1ccc(Cl)cc1F)Nc1nc2ccc(C(=O)O)cc2s1>>O=C(Cc1ccc(Cl)cc1F)Nc1nc2ccc(C(=O)Nc3ccc4[nH]c(=O)oc4c3)cc2s1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20090062258A1,COC(=O)c1ccsc1NC(=O)Nc1cccc(S(=O)(=O)N2CCCc3ccccc32)c1>>O=c1[nH]c2sccc2c(=O)n1-c1cccc(S(=O)(=O)N2CCCc3ccccc32)c1,,CC#N,CO,C[O-].[Na+],,test
US20150329542A1,COc1cc(C2CC2)c(-c2cc3c(cn2)cnn3C2CCCCO2)cc1F>>COc1cc(C2CC2)c(-c2cc3[nH]ncc3cn2)cc1F,,CO,,Cl,,test
US20090105474A1,CC(C)(C)OC(=O)c1ccc(Br)cc1Nc1ccc(F)cc1.COc1ccc(B(O)O)cn1>>COc1ccc(-c2ccc(C(=O)OC(C)(C)C)c(Nc3ccc(F)cc3)c2)cn1,,CC(=O)N(C)C,,O=C([O-])[O-].[Na+].[Na+],,test
US20070197478A1,Nc1c(NCc2ccccc2)cc(-c2ncco2)nc1NCc1ccccc1.O=C(n1ccnc1)n1ccnc1>>Nc1nc(-c2ncco2)cc2c1[nH]c(=O)n2Cc1ccccc1,,C1CCOC1,,,,test
US03948967,CCOC(=O)Cl.CNC(=O)N(O)c1ccc(Cl)c(Cl)c1>>CCOC(=O)ON(C(=O)NC)c1ccc(Cl)c(Cl)c1,,c1ccncc1,,CC(C)O,,test
US20040024034A1,CCOC(=O)C(C)(C)Oc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1>>Cc1oc(-c2ccccc2)nc1CCOc1ccc(OC(C)(C)C(=O)O)cc1,,CO,,[Na+].[OH-],,test
US20150190457A1,COC(=O)CBr.Cc1cc2[nH]nc(I)c2cc1OCc1ccccc1>>COC(=O)Cn1nc(I)c2cc(OCc3ccccc3)c(C)cc21,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04140713,CC(=O)c1ccc(F)c(S(N)(=O)=O)c1.CCNCC>>CCN(CC)c1ccc(C(C)=O)cc1S(N)(=O)=O,,CCO,,,,test
US20030008849A1,CC#CCOc1ccc(S(=O)(=O)N(C)C(C(=O)O)c2ccc(OCCCNC(=O)OCC)cc2)cc1.NO>>CC#CCOc1ccc(S(=O)(=O)N(C)C(C(=O)NO)c2ccc(OCCCNC(=O)OCC)cc2)cc1,,CN(C)C=O,,On1nnc2ccccc21,,test
US20070032496A1,CNC.O=c1[nH]ccc(Cl)c1[N+](=O)[O-]>>CN(C)c1cc[nH]c(=O)c1[N+](=O)[O-],,C1CCOC1,,,,test
US06080754,CCCc1ccc([N+](=O)[O-])cn1>>CCCc1ccc(N)cn1,[Pd],CCO,,[H][H],,test
US20140094453A1,CC(C)(C)OC(=O)N1CCC[C@H](CO)C1.N#Cc1c([N+](=O)[O-])cccc1[N+](=O)[O-]>>CC(C)(C)OC(=O)N1CCC[C@H](COc2cccc([N+](=O)[O-])c2C#N)C1,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20090264406A1,Cn1cc(-c2ccc3ncc(Br)n3n2)cn1.O=Cc1cn(S(=O)(=O)c2ccccc2)c2ncccc12>>Cn1cc(-c2ccc3ncc(C(O)c4cn(S(=O)(=O)c5ccccc5)c5ncccc45)n3n2)cn1,,C1CCOC1,,CC[Mg]Br,,test
US06713471B1,ClCCCBr.c1ccc2c(c1)CCCN2>>ClCCCN1CCCc2ccccc21,,C1COCCO1,CCOCC,CCN(CC)CC,,test
US20120178752A1,COC(=O)c1cccc(O)c1.C[C@H](O)C(=O)OCc1ccccc1>>COC(=O)c1cccc(O[C@H](C)C(=O)OCc2ccccc2)c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090143355A1,CC1(C)CNC(=O)c2cc([N+](=O)[O-])ccc21>>CC1(C)CNCc2cc([N+](=O)[O-])ccc21,,C1CCOC1,,,,test
US04060603,C[C@H]1CCN[C@@H]1C(=O)NC(=O)OC(C)(C)C.Cl>>C[C@H]1CCN[C@@H]1C(N)=O.Cl,,C1COCCO1,,,,test
US05574042,CC(=O)Nc1cccn2cc(C)nc12.Clc1cccc(Cl)c1CBr>>CC(=O)N(Cc1c(Cl)cccc1Cl)c1cccn2cc(C)nc12,,O,,[H-].[Na+],,test
US20120277423A1,C=C(C)C(=O)Cl.Cc1ccc(C)cc1>>C=CC(=O)c1cc(C)ccc1C,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20080269286A1,Fc1cc(F)cc(C2=CCNCC2)c1>>Fc1cc(F)cc(C2CCNCC2)c1,O=[Pt],CO,,Cl,,test
US20140275071A1,CCCO.CCn1c(=O)n(CCCO)c(=O)c2c1nc(Cl)n2Cc1ccc(Cl)cc1>>CCCOc1nc2c(c(=O)n(CCCO)c(=O)n2CC)n1Cc1ccc(Cl)cc1,,CCCO,,[Na],,test
US05258382,CCOC(=O)C(C(=O)OC1CC(C)CCC1C(C)C)n1cccc1C(=O)C(Cl)(Cl)Cl.NCc1ccc(Br)cc1F>>CC1CCC(C(C)C)C(OC(=O)C2C(=O)N(Cc3ccc(Br)cc3F)C(=O)c3cccn32)C1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20020087002A1,COc1cc(CO[C@H]2CN(C(=O)OC(C)(C)C)C[C@@H](OC[C@H](O)COS(=O)(=O)c3ccc(C)cc3)[C@@H]2c2ccc(OCCCOc3ccccc3[N+](=O)[O-])cc2)cc2ccccc12>>COc1cc(CO[C@H]2CN(C(=O)OC(C)(C)C)C[C@@H](OC[C@H]3CO3)[C@@H]2c2ccc(OCCCOc3ccccc3[N+](=O)[O-])cc2)cc2ccccc12,,CS(C)=O,,[Na+].[OH-],,test
US20070135631A1,CC(C)(C)[S@](N)=O.COc1cc(C(=O)Cc2ccccc2)ccc1F>>COc1cc(/C(Cc2ccccc2)=N/[S@](=O)C(C)(C)C)ccc1F,,C1CCOC1,,,,test
US20120295842A1,O=P(Cl)(Cl)Cl.Oc1nc2ccccc2c2ccc(F)cc12>>Fc1ccc2c(c1)c(Cl)nc1ccccc12,,CN(C)C=O,,,,test
US04012513,CC(=O)OC(C)=O.COc1ccc2c(c1)c(CCO)c(C)n2-c1ncnc2cc(Cl)ccc12>>COc1ccc2c(c1)c(CCOC(C)=O)c(C)n2-c1ncnc2cc(Cl)ccc12,,c1ccccc1,,,,test
US20150087663A1,CC[C@H](N)c1nc2cccc(Cl)c2c(=O)n1C1CC1.Cn1nnc(-c2c(N)ncnc2Cl)n1>>CC[C@H](Nc1ncnc(N)c1-c1nnn(C)n1)c1nc2cccc(Cl)c2c(=O)n1C1CC1,,CCCCO,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20090029976A1,CC(C)(C)OC(=O)N1CCC(O)CC1.CCOC(=O)c1cc2ccc(O)cc2s1>>CCOC(=O)c1cc2ccc(OC3CCN(C(=O)OC(C)(C)C)CC3)cc2s1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04109088,CN1CC(COc2cccc3c2CC=C3)OCC1=O>>CN1CCOC(COc2cccc3c2CC=C3)C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20030187023A1,CI.CN(C(=O)CCS(=O)(=O)c1cc2cc(Cl)ccc2[nH]1)C1CCN(C(=O)OC(C)(C)C)CC1>>CN(C(=O)CCS(=O)(=O)c1cc2cc(Cl)ccc2n1C)C1CCN(C(=O)OC(C)(C)C)CC1,,CN(C)C=O,,[H-].[Na+],,test
US03947434,Cc1cc(Nc2ccccc2)c2c(ccc3nc[nH]c32)n1.Cc1ccc(Cl)c(N)c1.Cl>>Cc1ccc(Cl)c(Nc2cc(C)nc3ccc4nc[nH]c4c23)c1.Cl,,CCO,,,,test
US05660762,CCCCCCCCCCC(=O)Cl.O=C(O)c1ccc(O)cc1>>CCCCCCCCCCC(=O)Oc1ccc(C(=O)O)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,Cl,test
US20150025093A1,BrBr.CCc1cc2c(NC3CCC(N(C)C)CC3)ncnc2s1>>CCc1sc2ncnc(NC3CCC(N(C)C)CC3)c2c1Br,,CC(=O)O,,,,test
US20020045654A1,CCc1cc(-c2cc(C(F)(F)F)nn2-c2ccc(S(C)(=O)=O)c(F)c2)ccc1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCc1cc(-c2cc(C(F)(F)F)nn2-c2ccc(S(C)(=O)=O)c(F)c2)ccc1OS(=O)(=O)C(F)(F)F,,ClCCl,,CCN(CC)CC,O,test
US05741892,CO[C@H](CC(=O)OC(C)(C)C)[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C>>CO[C@H](CC(=O)O)[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130072490A1,CCOC(=O)CC1(c2ccc(-c3ccc(-c4onc(C)c4C(O)C/C=C/c4ccc(Cc5ccccc5)cc4)cc3)cc2)CC1>>CCOC(=O)CC1(c2ccc(-c3ccc(-c4onc(C)c4C(O)CCCc4ccc(Cc5ccccc5)cc4)cc3)cc2)CC1,[Pd],CCO,,,,test
US20120302756A1,CC(C)(C)[S@](=O)N1CCC[C@@H]1c1ccc(Cl)cc1>>Clc1ccc([C@H]2CCCN2)cc1,,ClCCl,,Cl,,test
US20040072818A1,CCCCc1ccc(N=C=O)cc1.Clc1ccc2c(N3CCNCC3)ccnc2c1>>CCCCc1ccc(NC(=O)N2CCN(c3ccnc4cc(Cl)ccc34)CC2)cc1,,C1CCOC1,,CCCCCC,CCOC(C)=O,test
US20020151715A1,CC(F)(F)c1cc([N+](=O)[O-])ccc1F>>CC(F)(F)c1cc(N)ccc1F,,CO,,,,test
US20110065681A1,COC(=O)c1cc(O)cc(Br)c1.Cc1ccc(B(O)O)cc1>>COC(=O)c1cc(O)cc(-c2ccc(C)cc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080096874A1,O=C(O)CC1CCC(c2ccc(NC(=O)c3nnc(Nc4ccccc4F)o3)cc2)CC1>>O=C(Nc1ccc(C2CCC(CCO)CC2)cc1)c1nnc(Nc2ccccc2F)o1,,C1CCOC1,,B,,test
US20100076014A1,C/C=C(/OCc1ccccc1)O[Si](C)(C)C.O=C(O)c1ccc(C(O)c2ccc3c(cnn3-c3ccc(F)cc3)c2)cc1>>CC(C(=O)OCc1ccccc1)C(c1ccc(C(=O)O)cc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20040157866A1,CS(=O)(=O)O.Cc1ccc(-c2cc(C)ccc2C(=O)Nc2ccc3c(c2)CCN3C(=O)Cc2ccccn2)cc1>>CS(=O)(=O)O.Cc1ccc(-c2cc(C)ccc2C(=O)Nc2ccc3c(c2)CCN3C(=O)Cc2ccccn2)cc1,,C1CCOC1,CO,CC(C)OC(C)C,,test
US20070179138A1,CCOc1ccc(-c2cc(N)c([N+](=O)[O-])c(C#N)n2)cc1C(F)(F)F>>CCOc1ccc(-c2cc(N)c(N)c(C#N)n2)cc1C(F)(F)F,[Pd],CCOC(C)=O,,,,test
US20060148858A1,COC(=O)Cc1cn(C)nc1O.OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1C1CCCCC1>>Cn1cc(CC(=O)O)c(OCCCc2cn(-c3ccc(C(F)(F)F)cn3)nc2C2CCCCC2)n1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20060079550A1,COC(=O)[C@H](CCN=[N+]=[N-])NC(=O)OC(C)(C)C.O=S(=O)(Cl)c1ccc(Br)cc1>>COC(=O)[C@H](CCNS(=O)(=O)c1ccc(Br)cc1)NC(=O)OC(C)(C)C,[Pd],C1CCOC1,CCOC(C)=O,CCN(CC)CC,Cl,test
US09376441B2,CC(=O)OC(C)=O.COc1cc(-c2cc3ncn(C4CC4)c3c(O[C@H](C)[C@H]3CNC(=O)C3)n2)ccc1N1CCNCC1>>COc1cc(-c2cc3ncn(C4CC4)c3c(O[C@H](C)[C@H]3CNC(=O)C3)n2)ccc1N1CCN(C(C)=O)CC1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20110086834A1,C#C[Mg]Br.CC(=O)c1nc(C)cn1S(=O)(=O)c1ccc(C)cc1>>C#CC(C)(O)c1nc(C)cn1S(=O)(=O)c1ccc(C)cc1,,C1CCOC1,,,,test
US20080113946A1,CS(=O)(=O)c1nc(Cl)c2c(n1)COC2.O=C(Nc1ccc(S)cc1)C1CC1>>CS(=O)(=O)c1nc2c(c(Sc3ccc(NC(=O)C4CC4)cc3)n1)COC2,,CC(C)(C)O,,,,test
US20100273806A1,CC(C)OC(=O)c1cc(OC(C)C)cc(OC(F)(F)F)c1>>CC(C)Oc1cc(OC(F)(F)F)cc(C(=O)O)c1,,C1CCOC1,,O,[Li+].[OH-],test
US20040186118A1,C#CCNc1nc(Nc2ccc(N)cc2)ncc1Br.CCN=C=O>>C#CCNc1nc(Nc2ccc(NC(=O)NCC)cc2)ncc1Br,,CC#N,,,,test
US07582753B2,Nc1cccc(-c2noc(=O)[nH]2)c1.O=C(O)CN1N=C(C2CCCCC2)c2ccccc2N(CC(=O)C2CCCC2)C1=O>>O=C(CN1N=C(C2CCCCC2)c2ccccc2N(CC(=O)C2CCCC2)C1=O)Nc1cccc(-c2noc(=O)[nH]2)c1,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20080153868A1,CO.O=C1N[C@@H](Cc2cc(F)cc(F)c2)[C@@H]([C@H]2Cc3cccc(O)c3CN2C(c2ccccc2)c2ccccc2)O1>>COc1cccc2c1CN(C(c1ccccc1)c1ccccc1)[C@@H]([C@H]1OC(=O)N[C@H]1Cc1cc(F)cc(F)c1)C2,,CCOCC,CO,C[Si](C)(C)C=[N+]=[N-],,test
US20130184284A1,Clc1ccnc(Cl)n1.OB(O)c1ccc(OC(F)(F)F)cc1>>FC(F)(F)Oc1ccc(-c2ccnc(Cl)n2)cc1,,CC#N,,O,O=C([O-])[O-].[Na+].[Na+],test
US20060142366A1,CCCCCCCOc1ccc(O)cc1.N#Cc1ccc2c(ccn2CC2CO2)c1>>CCCCCCCOc1ccc(OCC(O)Cn2ccc3cc(C#N)ccc32)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20090105253A1,CCNC(=O)c1ccc(-n2nnc(C(=O)NCCO)c2COc2cccc(F)c2)cc1.O=C1CCC(=O)O1>>CCNC(=O)c1ccc(-n2nnc(C(=O)NCCOC(=O)CCC(=O)O)c2COc2cccc(F)c2)cc1,,c1ccncc1,,,,test
US20050004114A1,CC(C)(C)OC(=O)N1CCN(Cc2ccc(-c3ccc(-c4cccc5c4oc4ccccc45)cc3)cc2)CC1C(=O)[O-]>>O=C(O)C1CN(Cc2ccc(-c3ccc(-c4cccc5c4oc4ccccc45)cc3)cc2)CCN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150152112A1,C1COCCO1.Nc1ccc(-c2cnc([C@@H]3CCc4cc(-c5cc(Cl)ccc5-n5cnnn5)cc(=O)n43)[nH]2)cc1.O=C(Cl)OCCF>>O=C(Nc1ccc(-c2cnc([C@@H]3CCc4cc(-c5cc(Cl)ccc5-n5cnnn5)cc(=O)n43)[nH]2)cc1)OCCF.O=CO,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20120115862A1,COC(=O)c1ccc([N+](=O)[O-])cc1COc1cccc(NC(C)=O)c1>>CC(=O)Nc1cccc(OCc2cc([N+](=O)[O-])ccc2C(=O)O)c1,,CO,,[K+].[OH-],,test
US20030092711A1,CC1(C)OC(=O)Nc2ccc(B(O)O)cc21.Fc1cc(Br)cc(Br)c1>>CC1(C)OC(=O)Nc2ccc(-c3cc(F)cc(Br)c3)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150087585A1,CCOC(=N)C1(n2cc(F)cn2)CC1.Nc1cnc(N2CCC[C@@H](C(=O)N3CCCC3)C2)nc1N>>O=C([C@@H]1CCCN(c2ncc3nc(C4(n5cc(F)cn5)CC4)[nH]c3n2)C1)N1CCCC1,,CC(=O)O,,,,test
US20090156612A1,CCOC(=O)/C=C1\CCCC[C@@H]1n1cnc(C(=O)N2CCN(C(=O)OC(C)(C)C)C[C@H]2Cc2ccccc2)c1-c1ccccc1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ncn([C@H]3CCCC/C3=C\C(=O)O)c2-c2ccccc2)[C@H](Cc2ccccc2)C1,,CCO,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[Na+].[OH-],test
US20110311474A1,Cc1ccc(S(=O)(=O)n2ccc3c2ncc2ncc(C4CCC(N(Cc5ccccc5)Cc5ccccc5)CC4)n23)cc1>>c1ccc(CN(Cc2ccccc2)[C@@H]2CC[C@H](c3cnc4cnc5[nH]ccc5n34)CC2)cc1,,C1COCCO1,,[Na+].[OH-],,test
US20090099187A1,BrCCCCBr.COc1ccc(S(=O)(=O)Oc2ccc(Cl)c(Cl)c2)c2c1CC(NC(=O)C(F)(F)F)CC2>>COc1ccc(S(=O)(=O)Oc2ccc(Cl)c(Cl)c2)c2c1CC(N1CCCC1)CC2,,CC#N,,O,[Li+].[OH-],test
US20100099680A1,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](N)CC1.CCOC(=S)Nc1cc(Nc2ncc3c(n2)N(C(C)C)CC(=O)N3C)cc(S(C)(=O)=O)c1>>CC(C)N1CC(=O)N(C)c2cnc(Nc3cc(NC(=O)NC4CCC(NC(=O)OC(C)(C)C)CC4)cc(S(C)(=O)=O)c3)nc21,,CN(C)C=O,O,,,test
US20090142279A1,C[C@H]1CN(Cc2cccc(-c3cc(C#N)ccc3F)c2)CCN1C(=O)OCc1ccccc1>>C[C@H]1CN(Cc2cccc(-c3cc(CN)ccc3F)c2)CCN1C(=O)OCc1ccccc1,,C1CCOC1,,B,,test
US20030207400A1,CCOC(=O)c1nccn1C.O=[N+]([O-])O>>CCOC(=O)c1nc([N+](=O)[O-])cn1C,,O=S(=O)(O)O,,,,test
US04366160,Fc1cccc(F)c1N=C=S.O=C1c2ccccc2C(=O)N1CCNOCc1ccccc1>>O=C1c2ccccc2C(=O)N1CCN(OCc1ccccc1)C(=S)Nc1c(F)cccc1F,,c1ccccc1,,,,test
US20110201604A1,CNc1ccc(C(=O)OC)cc1N.CS(=O)(=O)c1ccc2nc(N)sc2c1.S=C(n1ccnc1)n1ccnc1>>COC(=O)c1ccc2c(c1)nc(Nc1nc3ccc(S(C)(=O)=O)cc3s1)n2C,,ClCCCl,,,,test
US20120101115A1,CC(=O)Cl.CC(C)C(=O)Nc1cc2c(c(-c3ccccc3Cl)c1)CCNC2>>CC(=O)N1CCc2c(cc(NC(=O)C(C)C)cc2-c2ccccc2Cl)C1,,CC(=O)N(C)C,,CCN(CC)CC,,test
US04851410,COC(=O)c1cnn(O)c1.ClCCCC1OCCO1>>COC(=O)c1cnn(OCCCC2OCCO2)c1,,CN(C)C=O,,[H][H],[H-].[Na+],test
US20070093521A1,CC(C)(C)OC(=O)N1CCC(Nc2nc3c([N+](=O)[O-])cccc3o2)CC1>>O=[N+]([O-])c1cccc2oc(NC3CCNCC3)nc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140228361A1,CCI.c1cnc2c(c1)CNC2>>CCN1Cc2cccnc2C1,,C1CCOC1,,[H-].[Na+],,test
US20070099990A1,Cc1c(NC(=O)CC(C)(C)C)cc2c(c1C)OC(C)(C)C2O.Nc1ccccc1OC(F)(F)F>>Cc1c(NC(=O)CC(C)(C)C)cc2c(c1C)OC(C)(C)C2Nc1ccccc1OC(F)(F)F,,CCCCCC,CCOC(C)=O,,,test
US20100305138A1,Nc1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)cn1.O=C=NCc1ccccc1>>O=C(NCc1ccccc1)Nc1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)cn1,,ClCCl,,,,test
US06329380B1,CN(c1nccc(-n2cnc3ccccc32)n1)C1CCCNC1.O=C=Nc1ccccc1>>CN(c1nccc(-n2cnc3ccccc32)n1)C1CCCN(C(=O)Nc2ccccc2)C1,,C1CCOC1,,,,test
US20110130393A1,CN(C)C(=O)c1ccc(Nc2nn(-c3ccccc3)cc2C#N)cc1.OO>>CN(C)C(=O)c1ccc(Nc2nn(-c3ccccc3)cc2C(N)=O)cc1,,CS(C)=O,O,CCO,[Na+].[OH-],test
US20120184543A1,COC(=O)c1ccc([N+](=O)[O-])c2c1CC(C)O2>>COC(=O)c1ccc(N)c2c1CC(C)O2,[Pd],CO,,[H][H],,test
US20060270632A1,Cc1cc(C)c(NC2CCN(C(=O)OC(C)(C)C)CC2)c(C)c1>>Cc1cc(C)c(NC2CCNCC2)c(C)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120010414A1,Cn1cnc(C(=O)N(Cc2ccc(F)c(Br)c2)C2CCOCC2)c1.OB(O)c1ccccc1>>Cn1cnc(C(=O)N(Cc2ccc(F)c(-c3ccccc3)c2)C2CCOCC2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04426387,CNC(=O)NC1CCN(Cc2ccc3ccccc3c2)CC1.O=C(Cl)c1ccccc1>>CN(C(=O)NC1CCN(Cc2ccc3ccccc3c2)CC1)C(=O)c1ccccc1,,Cc1ccccc1,,c1ccncc1,,test
US20090118305A1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.COc1[nH]ncc1Br>>COc1nn(C2CCN(C(=O)OC(C)(C)C)CC2)cc1Br,,CN(C)C=O,,Cl,[H-].[Na+],test
US20140094445A1,CC(=O)c1cc(Cl)ccc1O.NNC(=O)c1ccccc1>>C/C(=N\NC(=O)c1ccccc1)c1cc(Cl)ccc1O,,CC(=O)O,CO,,,test
US20150336920A1,CC(C)c1ccc2c(c1)OC1(O)c3c(cccc3[N+](=O)[O-])C(=O)C21N.O=C(O)C(=O)c1ccccc1>>CC(C)c1ccc2c(c1)OC1(O)c3c(cccc3[N+](=O)[O-])C(=O)C21NC(=O)C(=O)c1ccccc1,,CN(C)C=O,ClCCl,CCN=C=NCCCN(C)C,,test
US04876269,CCN(CC)CC.O[C@@H]1CCc2ccccc2[C@H]1N1CCCC1>>CN[C@@H]1c2ccccc2CC[C@H]1N1CCCC1,,ClCCl,,CS(=O)(=O)Cl,,test
US20090281088A1,CC1(c2ccc(Br)cc2)CO1.O=[N+]([O-])c1cnc(Br)[nH]1>>CC1(c2ccc(Br)cc2)Cn2cc([N+](=O)[O-])nc2O1,,CCN(CC)CC,,,,test
US20110311461A1,COC(=O)c1sccc1NC(C(=O)O[C@H]1CN2CCC1CC2)c1ccccc1.O=C(CBr)c1ccc(O)cc1>>COC(=O)c1sccc1NC(C(=O)O[C@H]1C[N+]2(CC(=O)c3ccc(O)cc3)CCC1CC2)c1ccccc1.[Br-],,CC#N,,CCOCC,,test
US20060111375A1,COc1cc2c(Oc3cc(C)c(C)nc3-c3ccccc3)ccnc2cc1OCc1ccccc1>>COc1cc2c(Oc3cc(C)c(C)nc3-c3ccccc3)ccnc2cc1O,,O=C(O)C(F)(F)F,,CS(=O)(=O)O,,test
US20150158864A1,C#CCNC(=O)c1c[nH]c2ncc(NC3CCNCC3)nc12.C=CC(=O)Cl>>C#CCNC(=O)c1c[nH]c2ncc(NC3CCN(C(=O)C=C)CC3)nc12,,C1CCOC1,O,CCN(C(C)C)C(C)C,,test
US20140296246A1,CCOc1nc2c(C(=O)c3c(F)cccc3F)cc(-c3c(C)noc3C)cc2n1C(=O)OC(C)(C)C.c1cnccn1>>Cc1noc(C)c1-c1cc(C(O)(c2cnccn2)c2c(F)cccc2F)c2[nH]c(=O)[nH]c2c1,,C1CCOC1,,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US20150038488A1,C[C@@H](Oc1cc(B2OC(C)(C)C(C)(C)O2)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1.Cc1cnc(Br)s1>>Cc1cnc(-c2cc(O[C@H](C)[C@H]3CNC(=O)C3)c3c(c2)ncn3C2CC2)s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,ClCCl,N#N,O=C([O-])[O-].[Na+].[Na+],test
US20050245554A1,CNC.CS(=O)(=O)c1ncc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1>>CN(C)c1ncc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1,,CCOCC,,CN(C)C=O,,test
US20100249163A1,COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(O)c2ccncc2)C2CC2)cc(OCCOC)c1>>COCCCc1cc(CN(C(=O)C2CNCCC2(O)c2ccncc2)C2CC2)cc(OCCOC)c1,,ClCCl,,Cl,,test
US20010031874A1,COc1ccc(C(=O)Nc2ccccc2)cc1N.COc1ccc(S(=O)(=O)Cl)cc1>>COc1ccc(S(=O)(=O)Nc2cc(C(=O)Nc3ccccc3)ccc2OC)cc1,,c1ccncc1,,,,test
US20070049578A1,COC(=O)C1CN(c2nccnc2C#N)CCN1C(=O)C=Cc1cccc(Cl)c1>>N#Cc1nccnc1N1CCN(C(=O)C=Cc2cccc(Cl)c2)C(C(=O)O)C1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20100160303A1,CC(=O)OC(C)=O.Cc1c(-c2ccc(C(N)=O)c3[nH]c4cc(CN)ccc4c23)cccc1N1Cc2ccccc2C1=O>>CC(=O)NCc1ccc2c(c1)[nH]c1c(C(N)=O)ccc(-c3cccc(N4Cc5ccccc5C4=O)c3C)c12,,C1CCOC1,,,,test
US20110065691A1,CC[Mg]Br.CON(C)C(=O)c1ccc(Br)cc1F>>CC(=O)Cc1ccc(Br)cc1F,,C1CCOC1,,CCOCC,,test
US20060094714A1,CCOC(=O)CC(=O)c1cccnc1Nc1cccc(C(F)(F)F)c1>>O=c1cc(O)c2cccnc2n1-c1cccc(C(F)(F)F)c1,,Cc1ccccc1C,,,,test
US05322847,Nc1ccc(O)cc1.O=[N+]([O-])c1cnccc1Cl>>O=[N+]([O-])c1cnccc1Nc1ccc(O)cc1,,CCO,,O=C([O-])O.[Na+],,test
US20110257151A1,CC1(C)Cc2cc(C(=O)O)ccc2NC1c1cccc([N+](=O)[O-])c1.CS(N)(=O)=O>>CC1(C)Cc2cc(C(=O)NS(C)(=O)=O)ccc2NC1c1cccc([N+](=O)[O-])c1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,[H-].[Na+],test
US06140100,COC(=O)c1ccc(O[Si](C)(C)C(C)(C)C)c(C(C)(C)C)c1>>CC(C)(C)c1cc(CO)ccc1O[Si](C)(C)C(C)(C)C,,Cc1ccccc1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20130040930A1,CI.Cc1cnc(N2CCN(C(=O)c3ccc(Br)cc3NS(C)(=O)=O)CC2)c(C)c1>>Cc1cnc(N2CCN(C(=O)c3ccc(Br)cc3N(C)S(C)(=O)=O)CC2)c(C)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20150203442A1,Nc1cc(O)c2c(c1)C(=O)c1cccc(O)c1C2=O.O=C(Cl)CI>>O=C(CI)Nc1cc(O)c2c(c1)C(=O)c1cccc(O)c1C2=O,,C1COCCO1,O,CO,ClCCl,test
US20150336949A1,CC(C)(C)OC(=O)N1CCN(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1.Cc1ccc(S(=O)(=O)n2cc(-c3ccn(Cc4cc(F)cc(F)c4)n3)c3cc(Br)cnc32)cc1>>Cc1ccc(S(=O)(=O)n2cc(-c3ccn(Cc4cc(F)cc(F)c4)n3)c3cc(-c4ccc(N5CCN(C(=O)OC(C)(C)C)CC5)cc4)cnc32)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20140121200A1,O=C(OCC1c2ccccc2-c2ccccc21)N1CCC2CN(c3nc(Cl)cc4nccnc34)CC21>>Clc1cc2nccnc2c(N2CC3CCNC3C2)n1,,ClCCl,,C1CCNCC1,,test
US20010051632A1,O=C(CBr)c1ccc([N+](=O)[O-])cc1.O=C1CCCC(=O)C1>>O=C(CC1C(=O)CCCC1=O)c1ccc([N+](=O)[O-])cc1,,ClC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US03948939,O=C(c1ccccc1)N(N=Cc1ccccc1)c1ccccc1F.O=C1CCC(C(=O)O)CC1>>O=C(O)C1CCc2c(c3cccc(F)c3n2C(=O)c2ccccc2)C1,,O,,CC(=O)O,Cl,test
US20050032786A1,COc1ccc(C(=O)O)c(S)c1.N#Cc1ccccn1>>COc1ccc2c(=O)nc(-c3ccccn3)sc2c1,,c1ccncc1,,,,test
US20130274244A1,Cc1nn(Cc2cccc(C3CC3)n2)c2cccc(NC(=O)c3cnc4cc(OCCN5CCN(C)[C@@H](C)C5)ccn34)c12.Cl.ClCCl>>Cc1nn(Cc2cccc(C3CC3)n2)c2cccc(NC(=O)c3cnc4cc(OCCN5CCN(C)[C@@H](C)C5)ccn34)c12.Cl.Cl,,CO,ClCCl,C1COCCO1,,test
US05633279,COCCOCOc1c(C/C=C(\C)CCC(=O)OC)c(OC)c(C)c2c1C(=O)OC2>>COCCOCOc1c(C/C=C(\C)CCC(=O)O)c(OC)c(C)c2c1C(=O)OC2,,CO,O,[Na+].[OH-],,test
US20080045521A1,COC(=O)[C@H](Cc1ccc(OCCc2ccc3c(n2)NCCC3C)cc1)NC(=O)c1c(Cl)cccc1Cl>>CC1CCNc2nc(CCOc3ccc(C[C@H](NC(=O)c4c(Cl)cccc4Cl)C(=O)O)cc3)ccc21,,CN(C)C=O,,O,[Li+].[OH-],test
US20030096835A1,COCCc1nc2c(N)nc3c(c2n1CCOCCN)CCCC3.O=C(Cl)c1ccccc1>>COCCc1nc2c(N)nc3c(c2n1CCOCCNC(=O)c1ccccc1)CCCC3,,CO,ClCCl,CCN(CC)CC,CCOCC,test
US20120189546A1,Cc1ccc(S(=O)(=O)O[C@H]2C[C@@H](OCc3ccccc3)C2)cc1>>Cc1ccc(S(=O)(=O)O[C@@H]2C[C@H](O)C2)cc1,,CCO,,,,test
US05807927,CN1C(=O)N(CCC(=O)O)C(C)(C)C1=O.COC(CN)OC>>COC(CNC(=O)CCN1C(=O)N(C)C(=O)C1(C)C)OC,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US05610295,CNCc1ccccc1.O=C(C(CCCl)c1ccccc1)N1CCCCCC1>>CN(CCC(C(=O)N1CCCCCC1)c1ccccc1)Cc1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20080019915A1,CC(C)(C)OC(=O)Nc1cccc(Br)n1.N#Cc1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)Nc1cccc(-c2ccc(C#N)cc2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100111900A1,COc1cc(CN2C(=O)CC[C@H]2C(C)(C)O[SiH2]C(C)(C)C)c(Br)cc1C(C)(C)C.OB(O)c1cccnc1OCc1ccccc1>>COc1cc(CN2C(=O)CC[C@H]2C(C)(C)O[SiH2]C(C)(C)C)c(-c2cccnc2OCc2ccccc2)cc1C(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,ClCCl,O=C([O-])[O-].[Na+].[Na+],,test
US20100105653A1,CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3ncc4cc(C#N)n(C5CCCC5)c4n3)nc2)CC1>>N#Cc1cc2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n1C1CCCC1,,CCOCC,,,,test
US20070213338A1,Clc1nnc(Cl)c2ccccc12.c1nc[nH]n1>>Clc1nnc(-n2cncn2)c2ccccc12,,CN(C)C=O,,[H-].[Na+],,test
US20090054508A1,CCOC(=O)c1cnc(Nc2ccccc2/C=C/c2n[nH]c3ccccc23)s1>>O=C(O)c1cnc(Nc2ccccc2/C=C/c2n[nH]c3ccccc23)s1,,CO,,O,[Na+].[OH-],test
US20060160864A1,CC(C(=O)OC(C)(C)C)=P(c1ccccc1)(c1ccccc1)c1ccccc1.CCOC(=O)CC1CCN(c2ccc(Br)cc2C=O)C1>>CCOC(=O)CC1CCN(c2ccc(Br)cc2/C=C(\C)C(=O)OC(C)(C)C)C1,,Cc1ccccc1,,O,,test
US20040132720A1,CCOC(=O)CBr.Oc1ccc(Br)c(F)c1>>CCOC(=O)COc1ccc(Br)c(F)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050026968A1,Nc1cccc(N2CCN(c3ccccn3)CC2)c1.O=C(Cl)c1ccc([N+](=O)[O-])o1>>O=C(Nc1cccc(N2CCN(c3ccccn3)CC2)c1)c1ccc([N+](=O)[O-])o1,,ClCCl,,CCN(CC)CC,,test
US20160046618A1,CCOC(=O)/C=C/[C@]12C[C@H]1[C@@](CF)(c1cc(N)ccc1F)N=C(N(COCC[Si](C)(C)C)C(=O)OC(C)(C)C)S2>>CC(C)(C)OC(=O)N(COCC[Si](C)(C)C)C1=N[C@](CF)(c2cc(N)ccc2F)[C@@H]2C[C@]2(/C=C/C(=O)O)S1,,CCO,,[Li+].[OH-],,test
US20090023761A1,Cc1cccc2cc(CN)c(-c3ccccc3Cl)nc12.Nc1ncc(Cl)c(Cl)n1>>Cc1cccc2cc(CNc3nc(N)ncc3Cl)c(-c3ccccc3Cl)nc12,,CCCCCO,,,,test
US20100311760A1,COc1nc(OCc2ccccc2)ccc1F.O=C1CCC(=O)N1Br>>COc1nc(OCc2ccccc2)c(Br)cc1F,,CN(C)C=O,,,,test
US20090253705A1,COC(=O)C1CCc2ccc[n+]([O-])c21.O=P(Cl)(Cl)Cl>>COC(=O)C1CCc2ccc(Cl)nc21,,CN(C)C=O,ClC(Cl)Cl,O,,test
US20150291595A1,CS(=O)(=O)Nc1cc(O)cc(O)c1.O=C(Cl)c1c(Cl)ncnc1Cl>>CS(=O)(=O)Nc1cc(O)cc(OC(=O)c2c(Cl)ncnc2Cl)c1,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US20140221339A1,Cc1c(Cl)cccc1NC(=O)c1cc(N)cc2[nH]c(N(C)C)nc12.O=C(Cl)c1c(F)cccc1Cl>>Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2c(F)cccc2Cl)cc2[nH]c(N(C)C)nc12,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20120309769A1,CCOC(=O)c1ccc2[nH]c(C)c(C)c2c1.Fc1ccc(CBr)c(F)c1>>CCOC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(F)cc1F,,CN(C)C=O,,[H-].[Na+],,test
US20120232056A1,COC(=O)c1ccc2nc(-c3cc4cc(OC)ccc4[nH]3)c(N(C)C(C)C)nc2c1>>COc1ccc2[nH]c(-c3nc4ccc(C(=O)O)cc4nc3N(C)C(C)C)cc2c1,,CO,O,[Na+].[OH-],,test
US05192785,O=C(O)COc1ccc(Cl)c(Cl)c1>>OCCOc1ccc(Cl)c(Cl)c1,,C1CCOC1,,B,,test
US20130225589A1,CCOC(=O)CC(=O)CC.COC(OC)N(C)C.CSC(=N)N>>CCOC(=O)c1cnc(SC)nc1CC,,CCOC(C)=O,,O=S(=O)(O)O,,test
US05872115,CN(C)c1cccc([N+](=O)[O-])c1C(=O)NC1CCN(C(c2ccccc2)c2ccccc2)CC1>>CN(C)c1cccc(N)c1C(=O)NC1CCN(C(c2ccccc2)c2ccccc2)CC1,[Ni],CCO,,,,test
US06660742B2,CCOC(=O)Cc1c([N+](=O)[O-])cc(NC(=O)OCc2ccccc2)c2ccccc12>>O=C(O)Cc1c([N+](=O)[O-])cc(NC(=O)OCc2ccccc2)c2ccccc12,,CCO,O,[Na+].[OH-],,test
US03993622,NNC(=O)c1ccccc1O.O=C(Cl)c1ccccc1O>>O=C(NNC(=O)c1ccccc1O)c1ccccc1O,,CC(=O)N(C)C,,O,,test
US20160264578A1,CCOC(=O)c1c(C)c(-c2ccc([N+](=O)[O-])cc2)cn1NC(=O)Nc1cccc(OC)c1F>>COc1cccc(-n2c(=O)[nH]n3cc(-c4ccc([N+](=O)[O-])cc4)c(C)c3c2=O)c1F,,ClCCl,,Cl,[Na+].[OH-],test
US05140034,CCOC(=O)c1nc[nH]c1C.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)c1ncn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c1C,,Cc1ccccc1,,CCN(CC)CC,,test
US20070232583A1,CN1CCNCC1.Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccnc(-c3cccc(S(=O)(=O)Cl)c3)c2)n1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccnc(-c3cccc(S(=O)(=O)N4CCN(C)CC4)c3)c2)n1,,C1CCOC1,CCOC(C)=O,,,test
US20060270632A1,CC(C)(C)[Si](C)(C)Cl.Cc1ccc(NC2CCN(CCC(O)C3CCCCC3)CC2)nc1>>Cc1ccc(NC2CCN(CCC(O[Si](C)(C)C(C)(C)C)C3CCCCC3)CC2)nc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20100184765A1,CNc1cc(-n2ncnc2Nc2cc(C(=O)O)ccc2C)ncn1.Nc1cccc(C(F)(F)F)c1>>CNc1cc(-n2ncnc2Nc2cc(C(=O)Nc3cccc(C(F)(F)F)c3)ccc2C)ncn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150266881A1,Cc1nnc(NC(=O)c2cc([C@@H]3C[C@H]3N)ccc2F)s1.Cl.Cl.O=C1CCC(F)(F)CC1>>Cc1nnc(NC(=O)c2cc([C@@H]3C[C@H]3NC3CCC(F)(F)CC3)ccc2F)s1.Cl.Cl,,CC(=O)O,CO,O=C([O-])O.[Na+],,test
US20100075948A1,CC(C)(C)CC1NC(C(=O)OC(C)(C)C)C(c2cccc(Br)c2)C1(C#N)c1ccc(Cl)cc1F.O=C(O)C(F)(F)F>>CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Br)c2)C1(C#N)c1ccc(Cl)cc1F.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20100029615A1,COC(=O)C12CCCC(C(=O)OC)(C1)C2>>COC(=O)C12CCCC(C(=O)O)(C1)C2,,CO,,,,test
US20150295178A1,C#C[Mg]Br.CCCCCCC(=O)CCl>>C#CC(O)(CCl)CCCCCC,,C1CCOC1,,,,test
US06514956B1,Brc1ccc(NC2CCCCC2)cc1.C[Si](C)(C)Cl>>C[Si](C)(C)N(c1ccc(Br)cc1)C1CCCCC1,,CCCCCC,,[Li]CCCC,,test
US20040002488A1,CCOC(CCl)(OCC)OCC.Nc1cccnc1S>>ClCc1nc2cccnc2s1,,CCO,,,,test
US05416087,O=S(Cl)Cl.OC1c2ccccc2-c2ccccc21>>ClC1c2ccccc2-c2ccccc21,,c1ccccc1,,,,test
US05493030,COC(=O)CC/C(C)=C/Cc1c(O)c2c(c(C)c1OC)COC2=O.COCCOCCl>>COCCOCOc1c(C/C=C(\C)CCC(=O)OC)c(OC)c(C)c2c1C(=O)OC2,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150291558A1,C[C@@H]1CC[C@@H](O)CN1C(=O)c1ccccc1-n1nccn1.Cc1c(I)ccnc1F>>Cc1c(I)ccnc1O[C@@H]1CC[C@@H](C)N(C(=O)c2ccccc2-n2nccn2)C1,,CS(C)=O,,[H-].[Na+],,test
US20100216788A1,Nc1ccc(Oc2cccc(C(=O)OC(c3ccccc3)c3ccccc3)c2)c(Cl)c1.O=C(OCCOCCn1ccc2ncnc(Cl)c21)c1ccccc1>>Cl.O=C(O)c1cccc(Oc2ccc(Nc3ncnc4ccn(CCOCCOC(=O)c5ccccc5)c34)cc2Cl)c1,,CC(C)O,,O=C([O-])O.[Na+],,test
US06979690B2,CCCCC(Br)C(=O)OCC.COc1nc(N)c(Cl)cc1C(=O)NCC1CCNCC1>>CCCCC(C(=O)OCC)N1CCC(CNC(=O)c2cc(Cl)c(N)nc2OC)CC1,,CN(C)C=O,O,CCN(CC)CC,[I-].[Na+],test
US20080045526A1,CCC=O.O=C(O)c1ccccn1>>CCC1OC(=O)c2ncccc21,,C1CCOC1,,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US20040242608A1,C=CCN.COC(=O)c1ccc(C)c(-n2c(S(C)(=O)=O)nc(OCc3ccc(F)cc3F)c(Cl)c2=O)c1>>C=CCNc1nc(OCc2ccc(F)cc2F)c(Cl)c(=O)n1-c1cc(C(=O)OC)ccc1C,CN(C)c1ccncc1,C1COCCO1,,CCOC(C)=O,,test
US20020128287A1,Cn1c(C(O)(c2ccc(Cl)cc2)c2ccc3c(c2)c(-c2cccc(C#C[Si](C)(C)C)c2)cc(=O)n3C)cnc1S>>Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2c(c1)c(-c1cccc(C#C[Si](C)(C)C)c1)cc(=O)n2C,[Ni],CCO,,,,test
US20060041128A1,CCC(c1nc2snc(C)c2c(=O)n1Cc1cccc(F)c1)N(CCCNC(=O)OC(C)(C)C)C(=O)c1ccc(C)cc1.Cl>>CCC(c1nc2snc(C)c2c(=O)n1Cc1cccc(F)c1)N(CCCN)C(=O)c1ccc(C)cc1.Cl,,C1COCCO1,,,,test
US05340831,COC(=O)c1ccc(CCBr)cc1.NC(=O)C(c1ccccc1)(c1ccccc1)C1CCNC1>>COC(=O)c1ccc(CCN2CCC(C(C(N)=O)(c3ccccc3)c3ccccc3)C2)cc1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US06608084B1,CC(CC(=O)O)c1ccc2c(c1)CCCN2.O=C1CCC(=O)N1C(=O)OCC1c2ccccc2-c2ccccc21>>CC(CC(=O)O)c1ccc2c(c1)CCCN2C(=O)OCC1c2ccccc2-c2ccccc21,,CC(C)=O,O,O=C([O-])O.[Na+],,test
US05863864,Cc1c(C(=O)O)ccc2c1C(=O)N(C)S2(=O)=O.O=S(Cl)Cl>>Cc1c(C(=O)Cl)ccc2c1C(=O)N(C)S2(=O)=O,,Cc1ccccc1,,,,test
US04229464,CCOC(=O)c1cc2c(OCc3ccccc3)cc(C)cc2[nH]1.N>>Cc1cc(OCc2ccccc2)c2cc(C(N)=O)[nH]c2c1,,CO,,,,test
US20080221188A1,O=[N+]([O-])c1cccc(Cl)c1NCCO>>Nc1cccc(Cl)c1NCCO,,CO,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US06229011B1,COC(=O)c1ccc(S(=O)(=O)NCc2cccc(OC(C)=O)c2)cc1Cl>>O=C(O)c1ccccc1,,C1CCOC1,CO,[Li+].[OH-],,test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCCCC1.O=[N+]([O-])c1c(O)ccc2[nH]ccc12>>COc1cc2cnc(Oc3ccc4[nH]ccc4c3[N+](=O)[O-])nc2cc1OCCCN1CCCCC1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20020052458A1,CCCC[Sn](=O)CCCC.OCC(CO)(CO)CO>>CCCC[Sn]1(CCCC)OCCCO1,,Cc1ccccc1,,,,test
US20120178623A1,Cc1cc(C)c(C2C(=O)CC(=CC3CCCCCC3)C2=O)c(C)c1>>Cc1cc(C)c(C2C(=O)CC(CC3CCCCCC3)C2=O)c(C)c1,[Pd],CO,,,,test
US03954860,CC=O.NS(=O)(=O)N1CCOCC1.c1ccc(OP(c2ccccc2)c2ccccc2)cc1>>CC(NS(=O)(=O)N1CCOCC1)P(=O)(c1ccccc1)c1ccccc1,,Clc1ccccc1,,,,test
US20070244159A1,CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)cc(C#N)c2[nH]1.OO>>CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)cc(C(N)=O)c2[nH]1,,CO,,[Na+].[OH-],,test
US20110287353A1,COc1ccc2cc(N(c3ccc(C)cc3)c3ccc4cc(OC)ccc4c3)ccc2c1>>Cc1ccc(N(c2ccc3cc(O)ccc3c2)c2ccc3cc(O)ccc3c2)cc1,,ClCCl,,BrB(Br)Br,,test
US20040014962A1,CC[C@@H](CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)NC(=O)c1csc(N2CC(O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)C2)n1>>CC[C@@H](CO)NC(=O)c1csc(N2CC(O)C2)n1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130065897A1,C=C(Cl)CSc1ccc(Br)cc1>>Cc1cc2cc(Br)ccc2s1,,CCOCC,,CCNCC,,test
US07053070B2,CCOC(=O)C(F)P(=O)(OCC)OCC.CSc1ncc(C=O)c(N)n1>>CSc1ncc2cc(F)c(=O)[nH]c2n1,,C1CCOC1,O,[Li]CCCC,[Cl-].[NH4+],test
US20150218111A1,O=C(O)CC(F)(F)F.O=C1COC(=O)C1>>O=C(CC(F)(F)F)C1=C(O)COC1=O,CN(C)c1ccncc1,CC#N,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20090197926A1,CCOC(=O)[C@H]1CC[C@@H](Oc2ccc([N+](=O)[O-])c(NC(=O)c3nnc(Nc4ccc(F)cc4)o3)c2F)CC1>>CCOC(=O)[C@@H]1CC[C@H](Oc2ccc(N)c(NC(=O)c3nnc(Nc4ccc(F)cc4)o3)c2F)CC1,[Pd],C1CCOC1,,,,test
US20060154955A1,CC(C)(C)OC(=O)Nc1ccc(-c2ccccc2)nc1C=O>>CC(C)(C)OC(=O)Nc1ccc(-c2ccccc2)nc1CO,,C1CCOC1,CCO,[BH4-].[Na+],,test
US04882326,CCOC(=O)CN1C(=O)C(N[C@@H](CSCCC2CCNCC2)C(=O)OCC)CCc2ccccc21.[OH-]>>O.O=C(O)CN1C(=O)C(N[C@@H](CSCCC2CCNCC2)C(=O)O)CCc2ccccc21,,CO,,CC(=O)O,,test
US05708181,CI.Cc1nc2cc(C)c(N(C)C)cc2[se]1>>Cc1cc2c(C)[n+](C)[se]c2cc1N(C)C.[I-],,ClC(Cl)Cl,,,,test
US20040138277A1,CCOC(=O)C(C)(Cc1ccc(O)cc1)Oc1ccccc1OC.Cc1ccc(S(=O)(=O)OCCc2nc(-c3ccc(-c4ccccc4)cc3)oc2C)cc1>>COc1ccccc1OC(C)(Cc1ccc(OCCc2nc(-c3ccc(-c4ccccc4)cc3)oc2C)cc1)C(=O)O,,CCO,,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20100331293A1,CCOC(=O)C(C)C(=O)Nc1cccc(F)c1Cl>>CC(C(=O)O)C(=O)Nc1cccc(F)c1Cl,,C1CCOC1,,,,test
US04435405,CN(C)CCCl.Cl.O=C(O)c1ccc(-c2cc3ccccc3[nH]c2=S)cc1>>CN(C)CCSc1nc2ccccc2cc1-c1ccc(C(=O)O)cc1.Cl,,CN(C)C=O,,[H][H],[H-].[Na+],test
US20060020019A1,CC[Si](CC)(CC)O[C@](C=C[N+](=O)[O-])(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1>>CC[Si](CC)(CC)O[C@](CCN)(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1,O=[Pt]=O,CO,,,,test
US20130011345A1,COC(=O)/C=C/CCC#CC#C[Si](C)(C)C>>C#CC#CCC/C=C/C(=O)O,,CCOC(C)=O,,[Na+].[OH-],,test
US20030096848A1,CCOC(=O)c1nnsc1Nc1ccccc1>>O=C(O)c1nnsc1Nc1ccccc1,,[Na+],[OH-],Cl,,test
US20110098302A1,CC(C)(C)C(=O)Cl.CCOC(=O)Cc1ccc(OC)c(Oc2ccc(N)cc2CN2CCOC2=O)c1>>CCOC(=O)Cc1ccc(OC)c(Oc2ccc(NC(=O)C(C)(C)C)cc2CN2CCOC2=O)c1,,ClCCl,,CCN(CC)CC,,test
US20150087585A1,BrCCBr.CSc1cnn(CC#N)c1>>CSc1cnn(C2(C#N)CC2)c1,,CS(C)=O,,[H-].[Na+],[Cl-].[NH4+],test
US20090149661A1,CCOC(=O)Cn1c(C(=O)OCC)c2c(c1C(=O)OCC)OCCCO2>>O=C(O)Cn1c(C(=O)O)c2c(c1C(=O)O)OCCCO2,,CC(C)=O,,O,[K+].[OH-],test
US20070249649A1,C#CCO.CC1CCN(c2cc(Br)ccc2[N+](=O)[O-])CC1>>CC1CCN(c2cc(C#CCO)ccc2[N+](=O)[O-])CC1,[Cu]I,C1COCCO1,CCOC(C)=O,CCN(CC)CC,,test
US20070032478A1,CN1CCN(c2ccc(N)cc2)CC1.Cn1nccc1C(=O)Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3=CO)c1>>CN1CCN(c2ccc(NC=C3C(=O)Nc4cc(C(=O)c5cccc(NC(=O)c6ccnn6C)c5)ccc43)cc2)CC1,,C1CCOC1,,,,test
US20110257179A1,CC(=O)NCN(c1ccccn1)c1nc(-c2cnn(CNC(C)=O)c2)c(C)s1>>CC(=O)NCn1cc(-c2nc(Nc3ccccn3)sc2C)cn1,,Cl,,,,test
US20100035883A1,C1CCNC1.O=Cc1ccc(C2Nc3cccc4c(=O)[nH]nc(c34)C2c2ccccc2)cc1>>O=c1[nH]nc2c3c(cccc13)NC(c1ccc(CN3CCCC3)cc1)C2c1ccccc1,,ClCCl,,CC(=O)O,[BH4-].[Na+],test
US20110105461A1,CCCN.Cc1ccc(S(=O)(=O)OC[C@H]2COc3c(F)cc(S(C)(=O)=O)cc3O2)cc1>>CCCNC[C@H]1COc2c(F)cc(S(C)(=O)=O)cc2O1,,CC#N,,,,test
US20130053574A1,O=C1CCCc2ccccc21>>OC1CCCc2ccccc21,,CCO,,[K+].[OH-],,test
US20110082181A1,CCOC(=O)C1(c2ccc(-c3ccc(-c4onc(C)c4CBr)cc3)cc2)CC1.OCCc1ccccc1>>Cc1noc(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1COCCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20060035920A1,CCn1c(=O)c2c(C)n(C3CCCCO3)nc2c2cc(-c3ccc(CN4CCCC4)s3)ccc21>>CCn1c(=O)c2c(C)[nH]nc2c2cc(-c3ccc(CN4CCCC4)s3)ccc21,,CO,,Cl,,test
US20100048940A1,CCC(=O)CC.OCC(O)CO>>CCC(=O)CC.OCC(O)CO,[Pd],,,,,test
US05434150,CNc1ccc(C(=O)OC)cc1[N+](=O)[O-].N#Cc1ccc(C(=O)Cl)cc1>>COC(=O)c1ccc(N(C)C(=O)c2ccc(C#N)cc2)c([N+](=O)[O-])c1,,O,,O=P(Cl)(Cl)Cl,,test
US05486446,CCCCOc1cc([N+](=O)[O-])c(OCCCC)cc1Cl.Sc1ccc(Cl)cc1>>CCCCOc1cc([N+](=O)[O-])c(OCCCC)c(Sc2ccccc2)c1Cl,,O,,CO,C[O-].[Na+],test
US05599829,CCI.Cc1c(Cl)cccc1NC(=S)NCC(N)=O.Cl>>CCSC1=NCC(=O)N1c1cccc(Cl)c1C.Cl,,Cl,,,,test
US20070105943A1,NCc1ccc(Oc2cccc(Cl)c2)s1.O=C(O)c1ccc2nccn2c1>>O=C(NCc1ccc(Oc2cccc(Cl)c2)s1)c1ccc2nccn2c1,,CN(C)C=O,O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20030069230A1,c1ccc(CN2CCc3c(ncnc3N3CCOCC3)C2)cc1>>c1nc2c(c(N3CCOCC3)n1)CCNC2,[Pd],CO,,O=C[O-].[NH4+],,test
US04479000,COc1cc(N)ccc1NC(=O)OCc1ccccc1.O=P(Cl)(Cl)Cl>>COc1cc(NP(=O)(Cl)Cl)ccc1NC(=O)OCc1ccccc1,,ClCCl,,c1ccncc1,,test
US20120129852A1,N#Cc1c(Cl)cncc1-c1ccc(OCc2ccccc2)cc1>>N#Cc1c(Cl)cncc1-c1ccc(O)cc1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20130345438A1,C[N+](=O)[O-].O=C1Nc2ccc(Cl)cc2C1=O>>O=C1Nc2ccc(Cl)cc2C1(O)C[N+](=O)[O-],,O,,,,test
US20080176813A1,CC(C)(C)[Si](C)(C)O[C@H]1C[C@@H](C(=O)c2ccccc2)[C@H](CC(=O)c2ccccc2)[C@@H](O)C1.CS(=O)(=O)Cl>>CC(C)(C)[Si](C)(C)O[C@H]1C[C@@H](C(=O)c2ccccc2)[C@H](CC(=O)c2ccccc2)[C@@H](OS(C)(=O)=O)C1,,ClCCl,,CCN(CC)CC,,test
US20020147192A1,Nc1ccc(CO)cc1.O=C(O)c1c(Cl)cncc1Cl>>O=C(Nc1ccc(CO)cc1)c1c(Cl)cncc1Cl,,O=S(Cl)Cl,,C1CCOC1,,test
US20140248268A1,CC(C)(C)OC(=O)c1c(NC(=S)NC(=O)c2ccccc2F)sc2c1CC(C)(C)OC2>>CC1(C)Cc2c(sc(NC(=S)NC(=O)c3ccccc3F)c2C(=O)O)CO1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05665719,COC(=O)C1CN(C(=O)OC(C)(C)C)CCC1Nc1ccccc1CO.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COC(=O)C1CN(C(=O)OC(C)(C)C)CCC1N1C(=O)OCc2ccccc21,,C1CCOC1,,CCN(CC)CC,O,test
US20020103247A1,CS(=O)(=O)Cl.OCCCCCc1ccc2c(ccn2-c2ccc(F)cc2)c1>>CS(=O)(=O)OCCCCCc1ccc2c(ccn2-c2ccc(F)cc2)c1,,ClCCl,,CCN(CC)CC,,test
US05610141,O=C(O)C(NCc1ccccc1)C(NCc1ccccc1)C(=O)O>>NC(C(=O)O)C(N)C(=O)O,[Pd],CC(=O)O,Cl,O,,test
US20060160865A1,CN(C(=O)Oc1ccc(N)cn1)c1ccccc1.O=C(Cl)c1cccc(Br)c1>>CN(C(=O)Oc1ccc(NC(=O)c2cccc(Br)c2)cn1)c1ccccc1,,CC#N,,CCN(CC)CC,ClCCl,test
US20090099178A1,CN1CCC[C@H]1CO.N#Cc1ccc2c(c1)c(-c1ccc3cc(O)ccc3c1)nn2C1CCCCO1>>CN1CCCC1COc1ccc2cc(-c3nn([C@@H]4CCCCO4)c4ccc(C#N)cc34)ccc2c1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110263630A1,O=C(/C=C/c1ccoc1)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5.O=C(O)C(=O)O>>O=C(/C=C/c1ccoc1)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5.O=C(O)C(=O)O,,CO,O,,,test
US20110053932A1,COc1cc(OC)c(Cl)c(NC(=O)c2cccc3c(Cl)ncnc23)c1Cl.Nc1ccc(CN2CCOCC2)cn1>>COc1cc(OC)c(Cl)c(NC(=O)c2cccc3c(Nc4ccc(CN5CCOCC5)cn4)ncnc23)c1Cl,,CCOC(C)=O,,C1COCCO1,,test
US20050026946A1,CC(C)(C)n1nc(C2CCC2)cc1N.CCOC(=O)CC(=O)c1ccccc1>>CC(C)(C)n1nc(C2CCC2)c2c(-c3ccccc3)cc(=O)[nH]c21,,CC(=O)O,,,,test
US20050272778A1,BrCc1ccc(I)c(Br)c1.O=C(Cc1ccccc1)c1ccccc1>>O=C(c1ccccc1)C(Cc1ccc(I)c(Br)c1)c1ccccc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US05399545,CCC(O)COc1cccc(C(F)(F)F)c1.O=C=NCc1ccccc1>>CCC(COc1cccc(C(F)(F)F)c1)OC(=O)NCc1ccccc1,CCN(CC)CC,CCCCCC,CCOC(C)=O,,,test
US20090118456A1,C=CCOC(CC(=O)OC)(CC(=O)OC)C(=O)OC.CCO[SiH](OCC)OCC>>CCO[Si](CCCOC(CC(=O)OC)(CC(=O)OC)C(=O)OC)(OCC)OCC,,Cc1ccccc1,,,,test
US20070179115A1,NCc1ccc(-c2cccc(OCc3ccccc3)c2)cc1.Nc1ncnc2c1nc(Br)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>Nc1ncnc2c1nc(NCc1ccc(-c3cccc(OCc4ccccc4)c3)cc1)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O,,CCCO,,CCN(C(C)C)C(C)C,,test
US20140037573A1,CC(C)(C)OC(=O)NC(=NCCC[C@H](NC(=O)OC(C)(C)C)C(=O)O)NC(=O)OC(C)(C)C>>N=C(N)NCCC[C@H](N)C(=O)O,CN(C)c1ccncc1,CS(C)=O,O,CCN=C=NCCCN(C)C,,test
US20150111891A1,C=Cc1ccc2c(OS(=O)(=O)C(F)(F)F)c([C@H](OC(C)(C)C)C(=O)OCC)c(C)cc2c1.O>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2cc(C=O)ccc2c1OS(=O)(=O)C(F)(F)F,,O,,C1CCOC1,,test
US20090124682A1,CC(C)(C)OC(=O)N[C@@H]1Cc2ccccc2[C@H]1CO[Si](C)(C)C(C)(C)C>>CC(C)(C)OC(=O)N[C@@H]1Cc2ccccc2[C@H]1CO,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040132733A1,CCO.N#Cc1ccccc1.N#N>>N#Cc1ccc(CCN)cc1,[Pd],,,CCOC(C)=O,,test
US20130310358A1,CCOC(=O)c1ccc(Oc2nc(-c3cccnc3)ncc2NC[C@@H]2CCCN2C(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)N1CCC[C@H]1CNc1cnc(-c2cccnc2)nc1Oc1ccc(C(=O)O)cc1,,CCO,,Cl,[Na+].[OH-],test
US20100298330A1,CC(C)(C)OC(=O)NC/C=C(/F)COc1ccc(C(=O)NC2CCCCC2)cc1.Cl>>Cl.NC/C=C(/F)COc1ccc(C(=O)NC2CCCCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150257385A1,CCOC(=O)C(Cl)C(C)=O.N=CN>>Cc1ncnc(O)c1Cl,,CO,,CO[Na],,test
US20060148858A1,CCOC(=O)CCc1ccc(O)c(OC)c1.Cc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO>>COc1cc(CCC(=O)O)ccc1OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US06316589B1,Ic1cccc(N=Nc2cccc(I)c2)c1>>Nc1ccc(-c2ccc(N)cc2I)c(I)c1,[Zn],CC(=O)O,,O=P(O)(O)O,,test
US05849755,CCC1=C(C)CN(C(=O)NC2COc3cc(OC)c(S(N)(=O)=O)cc3C2)C1=O.CN=C=S>>CCC1=C(C)CN(C(=O)NC2COc3cc(OC)c(S(=O)(=O)NC(=S)NC)cc3C2)C1=O,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20050239827A1,O=C(c1ccc(O)cc1O)c1ccc([N+](=O)[O-])cc1O>>Nc1ccc(C(=O)c2ccc(O)cc2O)c(O)c1,,CC(=O)O,,CCCCCC,CCOC(C)=O,test
US20130296554A1,C=C(C)[C@@H]1CC[C@]2(N3CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CC(C)(C)OC(=O)N1[C@@H]2CNC[C@H]1C2>>C=C(C)[C@@H]1CC[C@]2(NCCN3C[C@@H]4C[C@H](C3)N4C(=O)OC(C)(C)C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20140275027A1,CC(C)(C)OC(=O)N1CCC(c2cc3c(Cl)c(F)cnc3[nH]2)CC1.COc1ccc(F)cc1B(O)O>>COc1ccc(F)cc1-c1c(F)cnc2[nH]c(C3CCN(C(=O)OC(C)(C)C)CC3)cc12,,C1CCOC1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20050288290A1,COC(=O)c1cccoc1=O.NCc1ccc(F)cc1>>COC(=O)c1cccn(Cc2ccc(F)cc2)c1=O,CN(C)c1ccncc1,CN(C)C=O,,CCN=C=NCCCN(C)C,,test
US05098919,C1COCCN1.Cc1cn2c(c1C(=O)OC(C)C)SCC2CC(=O)O>>Cc1cn2c(c1C(=O)OC(C)C)SCC2CC(=O)N1CCOCC1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20090253758A1,C[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](Nc1ccc(C#N)c2sccc12)C(=O)NNC(=O)c1ccc(C#N)cc1>>C[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](Nc1ccc(C#N)c2sccc12)c1nnc(-c2ccc(C#N)cc2)o1,,ClCCl,,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110257151A1,CCOC(=O)c1ccc(N)cc1.Cc1ccc(F)cc1C=O>>CCOC(=O)c1ccc(N=Cc2cc(F)ccc2C)cc1,,CCO,,,,test
US06143764,CC(N=C=O)c1cccc2ccccc12.COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC>>COc1cc2nccc(Oc3ccc(NC(=O)NC(C)c4cccc5ccccc45)cc3)c2cc1OC,,Cc1ccccc1,,,,test
US20030027814A1,COc1cc(Br)cc(OC)c1N.Cl>>COc1cc(Br)cc(OC)c1Cl,,O,,O=N[O-].[Na+],,test
US05585385,CI.CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(-c2ccc(F)cc2)c2cccnc2c(=O)n1C>>CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(-c2ccc(F)cc2)c2ccc[n+](C)c2c(=O)n1C.[I-],,C1COCCO1,,,,test
US20080275029A1,CC(C)(C)OC(=O)NC(CCN)c1ccc(Cl)cc1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)NC(CCNC(=O)OCc1ccccc1)c1ccc(Cl)cc1,,ClCCl,ClCCl,CCN(C(C)C)C(C)C,,test
US20160237090A1,BrCc1ccccc1.CC1(C)CNC(=O)C1>>CC1(C)CC(=O)N(Cc2ccccc2)C1,,CN(C)C=O,,[H-].[Na+],,test
US20100197683A1,CCCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(C2CCC(OC)CC2)c2ncnn12.O=C([O-])O.[NH3+]O>>CCCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(C2CCC(OC)CC2)c2ncnn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US04876346,C#CCBr.CCN(CC)CC.CCOC(C)=O.Cc1ccccc1.O>>C#CCN(C)C[C@H](O)c1cccc(O)c1,,O,,C1CCOC1,,test
US03950332,N=c1c[n+](N2CCOCC2)[n-]o1.O>>NC(=O)CN(N=O)N1CCOCC1,,O,,Cl,[Na+].[OH-],test
US20120214766A1,CCOC(=O)C1(NC(=O)c2nn(-c3cnccn3)c3c2C[C@H]2C[C@@H]32)CCC1>>O=C(NC1(CO)CCC1)c1nn(-c2cnccn2)c2c1C[C@H]1C[C@@H]21,,C1COCCO1,,O,[BH4-].[Na+],test
US20020004511A1,CCOC(=O)c1sc(-c2cc3nccc(Nc4ccc5[nH]c(C)cc5c4)c3s2)nc1C>>Cc1cc2cc(Nc3ccnc4cc(-c5nc(C)c(CO)s5)sc34)ccc2[nH]1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120264734A1,C1COCCN1.CCN(c1cc(-c2ccc(C=O)c(F)c2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1>>CCN(c1cc(-c2ccc(CN3CCOCC3)c(F)c2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1,,CC(Cl)Cl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05412117,CC1(C)Oc2ccc([N+](=O)[O-])cc2CC1=O.CN=C=S>>CNC(=S)C1=C(O)C(C)(C)Oc2ccc([N+](=O)[O-])cc21,,CN(C)C=O,,Cl,CC(C)(C)[O-].[K+],test
US20090093497A1,COC(=O)C(C)(C)CC1CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)C(C)(C)CC1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04914188,CC(C)C[C@@H](C(=O)N[C@H](C(=O)N(C)[C@@H](C)C(=O)N[C@@H](C)C(=O)OCc1ccccc1)C(C)C)N(C)C(=O)OC(C)(C)C>>CN[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N(C)[C@@H](C)C(=O)N[C@@H](C)C(=O)OCc1ccccc1)C(C)C,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20110105509A1,COC(=O)Cn1c(C)cc2cc(F)ccc21.COc1ccc(C=O)cn1>>COC(=O)Cn1c(C)c(Cc2ccc(OC)nc2)c2cc(F)ccc21,,CC(Cl)Cl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US04327091,CCI.O=C(Nc1coc2ccccc2c1=O)C1NS(=O)(=O)c2ccccc2C1=O>>CCN1C(C(=O)Nc2coc3ccccc3c2=O)C(=O)c2ccccc2S1(=O)=O,,CN(C)C=O,,[H-].[Na+],,test
US04733012,Cl.O=Cc1ccc(CO)cc1>>O=Cc1ccc(CCl)cc1,,Cc1ccccc1,,,,test
US20030125339A1,CSc1ncc(C(=O)Nc2ccc(C(C)C)cc2)c(NCc2ccncc2)n1>>CC(C)c1ccc(NC(=O)c2cncnc2NCc2ccncc2)cc1,[Ni],CCO,,,,test
US20100216814A1,COc1ccc(C(C)=CBr)cc1.Cc1ccc2[nH]c3c(c2c1)CN(C)CC3>>COc1ccc(/C(C)=C/n2c3c(c4cc(C)ccc42)CN(C)CC3)cc1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20130225553A1,Nc1cc(Br)ccc1-c1ccnn1C1CCCC1.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2cc(Br)ccc2c2c1cnn2C1CCCC1,,CN1CCCC1=O,,,,test
US20030138663A1,CS(=O)(=O)Cl.Nc1cccc2cccnc12>>CS(=O)(=O)Nc1cccc2cccnc12,,c1ccncc1,,,,test
US20130130378A1,CC(=O)Nc1nc2c(ncn2COC(CO)CO)c(=O)[nH]1.COc1ccc(C(Cl)(c2ccccc2)c2ccc(OC)cc2)cc1>>COc1ccc(C(OCC(CO)OCn2cnc3c(=O)[nH]c(NC(C)=O)nc32)(c2ccccc2)c2ccc(OC)cc2)cc1,,c1ccncc1,,,,test
US20060128713A1,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCc2[nH]c3c(F)cccc3c2C1.CS(=O)(=O)Cl>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCc2c(c3cccc(F)c3n2S(C)(=O)=O)C1,,ClCCl,,CCN(CC)CC,,test
US20060122263A1,COc1ccc(C=O)cc1.N[C@H]1CC[C@@H](C(c2ccccc2)c2ccccc2)OC1>>COc1ccc(CN[C@H]2CC[C@@H](C(c3ccccc3)c3ccccc3)OC2)cc1,,CO,ClCCCl,CC(=O)O,[BH3-]C#N.[Na+],test
US20020099047A1,Cl.Clc1ccc(CCN2CCCC[C@@H]2CN2c3ccccc3COc3ccccc32)cc1>>Cl.Clc1ccc(CCN2CCCC[C@@H]2CN2c3ccccc3COc3ccccc32)cc1,,ClCCl,,CCOC(C)=O,,test
US20020068737A1,CC(C)(C)OC(=O)NC(CO)c1ccc(F)c(F)c1>>O=C1NC(c2ccc(F)c(F)c2)CO1,,C1CCOC1,,[H-].[Na+],,test
US20070191364A1,CC(=O)Cl.NC1CCC(=O)CC1>>CC(=O)NC1CCC(=O)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150307493A1,CC(C)C1Oc2c(Br)cc(C#N)cc2N(C)C1=O.Cc1ccc(S(=O)(=O)n2ccc3c(B4OC(C)(C)C(C)(C)O4)cn(C)c(=O)c32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(-c4cc(C#N)cc5c4OC(C(C)C)C(=O)N5C)cn(C)c(=O)c32)cc1,,C1COCCO1,O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20090163469A1,CC(=O)Nc1nc(C)c(-c2csc(Nc3cccnc3)n2)s1>>Cc1nc(N)sc1-c1csc(Nc2cccnc2)n1,,CCO,,Cl,O=C([O-])O.[Na+],test
US20160096830A1,Br.CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)C1CCCC1)C(=O)C=[N+]=[N-]>>CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)C1CCCC1)C(=O)CBr,,CCOC(C)=O,,CC(=O)O,O=C([O-])O.[Na+],test
US20060287522A1,COc1ccccc1-c1ccc(C(=O)N2Cc3ccc(C(=O)C(Cl)(Cl)Cl)n3Cc3ccccc32)cc1.NCc1cncc(Br)c1>>COc1ccccc1-c1ccc(C(=O)N2Cc3ccc(C(=O)NCc4cncc(Br)c4)n3Cc3ccccc32)cc1,,CC#N,,CCN(CC)CC,CS(C)=O,test
US20080139639A1,CCOC(=O)c1cc(-c2ccccc2)n(S(=O)(=O)c2cccs2)c1>>O=S(=O)(c1cccs1)n1cc(CO)cc1-c1ccccc1,,C1CCOC1,Cc1ccccc1,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20140128373A1,NCC1CC1.O=C(c1c(F)ccc(NS(=O)(=O)N2CCCC2)c1F)c1c[nH]c2ncc(F)c(I)c12>>O=C(c1c(F)ccc(NS(=O)(=O)N2CCCC2)c1F)c1c[nH]c2ncc(F)c(NCC3CC3)c12,,CC(C)O,,,,test
US20020156081A1,CN1CCN(CCCn2nc(I)c3c(N)ncnc32)CC1.COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1NC(=O)c1cc2ccccc2n1C>>COc1cc(-c2nn(CCCN3CCN(C)CC3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20100292206A1,CC(C)(C)c1ccccc1OC1CNC1.O=C(Cl)c1ccccc1>>CC(C)(C)c1ccccc1OC1CN(C(=O)c2ccccc2)C1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20140288123A1,CC(C)C(Oc1ccccc1)c1ccc(C(=O)O)cc1.Cc1cc(C)c(CN)c(O)n1>>Cc1cc(C)c(CNC(=O)c2ccc(C(Oc3ccccc3)C(C)C)cc2)c(O)n1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04039316,CCC(=O)Nc1cccc(NC(=O)CC(C)(OC)OC)c1>>CCC(=O)Nc1cccc(NC(=O)/C=C(/C)OC)c1,,Cc1ccccc1,,,,test
US20100137313A1,C1COCCN1.NS(=O)(=O)CCCCl>>NS(=O)(=O)CCCN1CCOCC1,,C1COCCO1,ClC(Cl)Cl,[I-].[Na+],,test
US20150344437A1,Cn1[nH]c(-c2ccccc2)c(C=O)c1=O>>Cc1c(-c2ccccc2)nn(C)c1O,,CC(=O)O,,,,test
US20070149561A1,O=S(=O)(c1ccccc1)n1c(I)cc2c(Br)ccnc21.OCc1cccc(B(O)O)c1>>O=S(=O)(c1ccccc1)n1c(-c2cccc(CO)c2)cc2c(Br)ccnc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])O.[Na+],,test
US20130317065A1,COc1ccc2c(Cc3cccc(C(=O)OCc4ccccc4)n3)c(-c3ccccc3)[nH]c2c1.O=S(=O)(Cl)c1ccccc1>>COc1ccc2c(Cc3cccc(C(=O)OCc4ccccc4)n3)c(-c3ccccc3)n(S(=O)(=O)c3ccccc3)c2c1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US04814346,O=c1c(-c2ccc([N+](=O)[O-])cc2)coc2cc(O)c(O)cc12>>Nc1ccc(-c2coc3cc(O)c(O)cc3c2=O)cc1,[Ni],C1COCCO1,CCO,,,test
US20100034766A1,CC(OC(C)(C)C=O)C1CCCC(C)(C)C1.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)C=CC(C)(C)OC(C)C1CCCC(C)(C)C1,,COCCOC,,CC(=O)O,[H-].[Na+],test
US03941802,COC(OC)OC.NCC=O.Nc1ccccc1Cc1ccccc1>>c1ccc(Cc2ccccc2-n2ccnc2)cc1,Cl[Ti](Cl)(Cl)Cl,COCCOC,,,,test
US20090143353A1,Cc1c(C#N)c(N)c(OC(=O)C(C)(C)C(=O)[O-])c(F)c1-c1ccccc1.Cc1ccccc1>>Cc1c(-c2ccccc2)c(F)c2oc(C(C)(C)C(=O)OCc3ccccc3)nc2c1C#N,,CCOC(C)=O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20030171395A1,NC(=O)C(=O)c1c[nH]c2ccncc12>>NCCc1c[nH]c2ccncc12,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06048868,CC(=O)OC(C)=O.CC1=C2N=c3ccccc3=C2CCN1>>C=C1c2[nH]c3ccccc3c2CCN1C(C)=O,,c1ccncc1,,CCOC(C)=O,,test
US20040063735A1,C=C(C(=O)OC)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.CC1(C)CNCc2cn[nH]c21>>COC(=O)C(CN1Cc2cn[nH]c2C(C)(C)C1)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,CO,,,,test
US20070059364A1,CN(C)CCc1c[nH]c2c(N)cccc12.O=S(=O)(Cl)c1cccc2ccccc12>>CN(C)CCn1ccc2cccc(NS(=O)(=O)c3cccc4ccccc34)c21,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20100016388A1,O=P(O)(O)O.O=c1[nH]c2c(O)ccc([C@@H](O)CNCCSCCCNCCc3ccccc3Cl)c2s1>>O=P(O)(O)O.O=c1[nH]c2c(O)ccc([C@@H](O)CNCCSCCCNCCc3ccccc3Cl)c2s1,,CO,,,,test
US20010027196A1,CS(=O)(=O)c1nc(N)nc(-c2ccco2)c1C#N.OCCCCc1ccccc1>>N#Cc1c(OCCCCc2ccccc2)nc(N)nc1-c1ccco1,,COCCOC,,C1CCC2=NCCCN2CC1,,test
US20120277212A1,CC(C)(C)ON=c1cc(-c2cc3ccccc3cn2)oc2cc(C#Cc3cccc(N)c3)ccc12.CI>>CNc1cccc(C#Cc2ccc3c(=NOC(C)(C)C)cc(-c4cc5ccccc5cn4)oc3c2)c1,,CN(C)C=O,CN(C)C=O,[H-].[Na+],,test
US20040186103A1,C[C@H](C(=O)O)c1ccc(Cl)cc1.Cc1ccc(NC(=O)C(C)C)cc1C1CCN(CCCN)CC1>>Cc1ccc(NC(=O)C(C)C)cc1C1CCN(CCCNC(=O)[C@@H](C)c2ccc(Cl)cc2)CC1,,CO,,,,test
US20010027196A1,CS(=O)(=O)c1nc(N)nc(-c2ccc3c(c2)OCO3)c1C#N.OC1CCCCC1>>N#Cc1c(OC2CCCCC2)nc(N)nc1-c1ccc2c(c1)OCO2,,COCCOC,,C1CCC2=NCCCN2CC1,,test
US20040204450A1,CCOC(=O)N1c2ccc(C(F)(F)F)cc2C(C(OS(C)(=O)=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1CC>>CCOC(=O)N1c2ccc(C(F)(F)F)cc2[C@H](Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C[C@H]1CC,,CN(C)C=O,,[BH4-].[Na+],,test
US20100317757A1,C=CCBr.CN(C)C=O.Cc1ccccc1O>>C=CCOCC=C.Cc1ccccc1O,,CN(C)C=O,,[H-].[Na+],,test
US20060293319A1,O=C(O)c1ccncc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>O=C=Nc1ccncc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20090318431A1,CN1C(=O)OCc2cc(N)cc(F)c21.O=C(Cl)OCc1ccccc1>>CN1C(=O)OCc2cc(NC(=O)OCc3ccccc3)cc(F)c21,,ClCCl,O,c1ccncc1,,test
US08614321B2,COc1ccc(B(O)O)cc1.Nc1cnc(Br)cn1>>COc1ccc(Nc2cnc(Br)cn2)cc1,CN(C)c1ccncc1,ClCCl,,,,test
US20100173933A1,COc1ccc(C(N)=O)cc1.O=C(CCl)CCl>>COc1ccc(-c2nc(CCl)co2)cc1,,Cc1ccccc1,,,,test
US20070244095A1,CC(C)OC(=O)N1CCCC(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nn[nH]n2)c2cc3c(cc21)CCC3.CO>>CC(C)OC(=O)N1CCCC(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(C)n2)c2cc3c(cc21)CCC3,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160060528A1,C1CCOC1.CCOC(=O)CC(=O)OCC.CCOC(=O)CCCCCCCBr>>CCOC(=O)CCCCCCCC(CC)(C(=O)OCC)C(=O)OCC,,C1CCOC1,O,Cl,CC(C)[N-]C(C)C.[Li+],test
US20020143009A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)CC(C)N3C(=O)CO)C(=O)O1>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)C[C@@H](C)N3C(=O)CO)C(=O)O1,,CCO,,,,test
US05972975,Cc1cc(C)nc(-n2c(C)ccc2C)c1.Cc1ccc(C)n1CCCBr>>Cc1cc(CCCCn2c(C)ccc2C)nc(-n2c(C)ccc2C)c1,,CCCCCC,CCOCC,C1CCOC1,[Li]CCCC,test
US20140031385A1,Cc1cccc(-n2nc(C)cc2O)n1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1cccc(-n2nc(C)cc2OS(=O)(=O)C(F)(F)F)n1,,ClCCl,,CCN(CC)CC,,test
US20140148443A1,CCOc1cc(Cl)c(S(=O)(=O)NC(C)(C)C)cc1C1=N[C@@](C)(c2ccc(Cl)cc2)[C@@](C)(c2ccc(Cl)cc2)N1.O=C(Cl)Cl>>CCOc1cc(Cl)c(S(=O)(=O)NC(C)(C)C)cc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)Cl,,CCN(CC)CC,,,,test
US05380721,CCOC(=O)CBr.COc1cc([N+](=O)[O-])ccc1O>>CCOC(=O)COc1ccc([N+](=O)[O-])cc1OC,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120289504A1,Cc1ccc(NC[C@@H]2CN(C(=O)OC(C)(C)C)CCO2)c(N)c1.O=Cc1c(F)cc(C(=O)O)cc1F>>Cc1ccc2c(c1)nc(-c1c(F)cc(C(=O)O)cc1F)n2C[C@@H]1CN(C(=O)OC(C)(C)C)CCO1,,CO,,CC(=O)O,,test
US20060084643A1,CCC=O.COCC[C@H]1CN(C2=Nc3ccccc3Nc3sc(C(F)(F)F)nc32)CCN1>>CCCN1CCN(C2=Nc3ccccc3Nc3sc(C(F)(F)F)nc32)C[C@@H]1CCOC,,CC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130324576A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(Cl)c(F)c2)CC1.Cl>>Cl.Fc1cc(OC2CCNCC2)ccc1Cl,,C1COCCO1,,,,test
US20130102776A1,COc1ccc2c(c1CCCCC1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccccc13)C2=O>>COc1ccc2c(c1CCCCC1CCNCC1)O/C(=C\c1n[nH]c3ccccc13)C2=O,,C1COCCO1,ClCCl,Cl,,test
US20120122848A1,CS(=O)(=O)Cl.Cc1c2c(cc(OCc3ccccc3)c1Nc1ccccc1N)[C@@]13CCCC[C@H]1[C@@H](C2)N(C(=O)OCc1ccccc1)CC3>>Cc1c2c(cc(OCc3ccccc3)c1Nc1ccccc1NS(C)(=O)=O)[C@@]13CCCC[C@H]1[C@@H](C2)N(C(=O)OCc1ccccc1)CC3,,ClCCl,,O,,test
US20150329518A1,COC(=O)c1ccc(CC[C@H]2C(=O)C=C[C@@H]2/C=C/C(Cc2ccc3ccccc3c2)O[Si](C)(C)C(C)(C)C)cc1>>COC(=O)c1ccc(CC[C@H]2C(=O)CC[C@@H]2/C=C/C(Cc2ccc3ccccc3c2)O[Si](C)(C)C(C)(C)C)cc1,,Cc1ccccc1,,,,test
US06593437B1,CC(=O)O.Cc1c(C)c(C)[c-](C)c1C.[Fe+2].[N-]=[N+]=NC(=O)[c-]1cccc1>>Cc1c[c-](C)c(C)c1C.Cc1ccc[c-]1CC(N)=O.[Fe+2],,CC(=O)OC(C)=O,,,,test
US20040176324A1,CC(=O)OC(C)=O.O=[N+]([O-])c1cccc2c(Cl)cccc12>>CC(=O)Nc1cccc2c(Cl)cccc12,[Fe],,,,,test
US05569659,CC(C)Br.O=[N+]([O-])c1ccc(F)cc1O>>CC(C)Oc1cc(F)ccc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04325970,CC(=O)OC(C)=O.CCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@H](C)CC(=O)[C@@H]1C/C=C\CCCC(=O)O>>CCCCC(C)(C)[C@@H](/C=C/[C@@H]1[C@H](C)CC(=O)[C@@H]1C/C=C\CCCC(=O)O)OC(C)=O,CN(C)c1ccncc1,CCN(CC)CC,,,,test
US20070105943A1,N#Cc1ccc([N+](=O)[O-])s1.Oc1cccc(Br)c1>>N#Cc1ccc(Oc2cccc(Br)c2)s1,,CS(C)=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US05034417,CC(=O)c1ccc(Sc2ccc(F)cc2F)c(NS(C)(=O)=O)c1.O=[N+]([O-])O>>CC(=O)c1cc(NS(C)(=O)=O)c(Sc2ccc(F)cc2F)cc1[N+](=O)[O-],,CC(=O)O,,,,test
US06448266B1,CCOC(=O)CC(C[N+](=O)[O-])C1(NC(=O)OC(C)(C)C)CC(OCc2ccccc2)C1>>CC(C)(C)OC(=O)NC1(C2CNC(=O)C2)CC(OCc2ccccc2)C1,[Ni],CCO,,[H][H],,test
US20140135270A1,CC(C)(C)OC(=O)c1ccc(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)cc1.CO>>COC(=O)[C@H](Cc1ccc(C(=O)OC(C)(C)C)cc1)NC(=O)OCC1c2ccccc2-c2ccccc21,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080312255A1,CC(=O)NN.CCOC(=O)c1sc(Cl)nc1C(=O)Cl>>CCOC(=O)c1sc(Cl)nc1C(=O)NNC(C)=O,,ClCCl,,Cc1cccc(C)n1,,test
US20020094935A1,CCOC(=O)N=C=S.COc1cc(OC)nc(N)n1>>CCOC(=O)NC(=S)Nc1nc(OC)cc(OC)n1,,C1CCOC1,,,,test
US04754050,O=C1CCCc2nc3ccccc3c(NCc3ccc(OCc4ccccc4)cc3)c21>>OC1CCCc2nc3ccccc3c(NCc3ccc(OCc4ccccc4)cc3)c21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040132727A1,COc1cc2nccc(Oc3ccc(N)c(C)c3C)c2cc1OC.O=C(N=C=S)c1ccc(Cl)cc1>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4ccc(Cl)cc4)c(C)c3C)c2cc1OC,,CCO,,Cc1ccccc1,,test
US20090298823A1,COc1ccc(N)cc1.Cc1ccc(S(=O)(=O)n2cc(I)c3c(Cl)nc(Cl)nc32)cc1>>COc1ccc(Nc2nc(Cl)nc3c2c(I)cn3S(=O)(=O)c2ccc(C)cc2)cc1,,C1COCCO1,CCOC(C)=O,CCN(C(C)C)C(C)C,O,test
US20050059650A1,O=P(Cl)(Cl)Cl.O=c1cc[nH]c2c(I)cccc12>>Clc1ccnc2c(I)cccc12,,CN(C)C=O,,,,test
US07247645B2,CCOC(=O)CC(=O)CCl.OCCC(c1ccccc1)c1ccccc1>>O=C(CCl)CC(=O)OCCC(c1ccccc1)c1ccccc1,,Cc1ccccc1,,,,test
US20060106084A1,CC(C)I.COc1cccc(C(=O)c2n[nH]c3c(C(F)(F)F)cccc23)c1>>COc1cccc(C(=O)c2nn(C(C)C)c3c(C(F)(F)F)cccc23)c1,,CN(C)C=O,,[H-].[Na+],,test
US20060217372A1,COc1ccc(CCCl)cc1.N[C@H]1CC[C@H](O)CC1>>COc1ccc(CCN[C@@H]2CC[C@@H](O)CC2)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050182072A1,NC(=O)c1ccccc1NC(=O)c1ccnc(Cl)c1>>O=c1[nH]c(-c2ccnc(Cl)c2)nc2ccccc12,,CC(C)=O,O,Cl,[Na+].[OH-],test
US20100210680A1,CCOC(=O)Cl.COc1cc(C)c2c(c1)[C@@H]1CNC[C@@H]1OC2>>CCOC(=O)N1C[C@@H]2OCc3c(C)cc(OC)cc3[C@@H]2C1,,O,,C1CCOC1,O=C([O-])O.[Na+],test
US20150376213A1,CCCCCC1CC1CC1CC1CCCCCCCC(=O)OC[C@H](COCc1ccccc1)OC(=O)CCCCCCCC1CC1CC1CC1CCCCC>>CCCCCC1CC1CC1CC1CCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCCC1CC1CC1CC1CCCCC,[Pd],CCO,,,,test
US20060166964A1,COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(C(=O)N1CCOCC1)Cc1ccccc1-3>>O=C(O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(C(=O)N1CCOCC1)Cc1ccccc1-3,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20020006934A1,CS(=O)(=O)Cl.Cc1ccn2cc(-c3ccc(CCCCO)cc3)nc2c1>>Cc1ccn2cc(-c3ccc(CCCCOS(C)(=O)=O)cc3)nc2c1,,ClCCl,,CCN(CC)CC,,test
US20110294781A1,NNc1cc(N2CCOCC2)n2ncc(-c3ccccn3)c2n1.O=Cc1c[nH]c2ccccc12>>C(=NNc1cc(N2CCOCC2)n2ncc(-c3ccccn3)c2n1)c1c[nH]c2ccccc12,,CCO,,CC(=O)O,,test
US04954163,Cc1cc(C)n2nc(S(=O)(=O)Cl)nc2n1.Nc1c(Cl)cc(Cl)cc1Cl>>Cc1cc(C)n2nc(S(=O)(=O)Nc3c(Cl)cc(Cl)cc3Cl)nc2n1,,C1CCOC1,CCCCCC,,,test
US20100317675A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.O=C(Nc1ccccc1)c1cn2cc(I)ccc2n1>>C=C(OCC)c1ccc2nc(C(=O)Nc3ccccc3)cn2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US20090005353A1,CC(C)(C)OC(=O)NC1CNC1.FC(F)(F)c1cnc(Cl)c(Cl)c1>>CC(C)(C)OC(=O)NC1CN(c2ncc(C(F)(F)F)cc2Cl)C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130096113A1,CCOC(OCC)OCC.Nc1cc(F)cnc1N>>Fc1cnc2[nH]cnc2c1,,O=CO,,,,test
US04013686,COC(=O)C1=C(O)c2ccccc2S(=O)(=O)C1.Nc1ccccc1>>O=C(Nc1ccccc1)C1=C(O)c2ccccc2S(=O)(=O)C1,,Cc1ccccc1C,,,,test
US20100222318A1,Cc1cc(CN(C)C(=O)OC(C)(C)C)ccc1-c1nnc(-c2nc(-c3ccc(S(=O)(=O)C(C)C)cc3)cnc2N)o1>>CNCc1ccc(-c2nnc(-c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)o2)c(C)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150148327A1,CC(=O)c1cncc(Br)c1.C[Si](C)(C)C(F)(F)F>>CC(O)(c1cncc(Br)c1)C(F)(F)F,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110319394A1,CCn1c(=O)n(-c2ccc(O)cc2)c2ncc(C#N)cc21.Cn1c(S(C)(=O)=O)nc2cccnc21>>CCn1c(=O)n(-c2ccc(Oc3nc4cccnc4n3C)cc2)c2ncc(C#N)cc21,,CN(C)C=O,CO,[H-].[Na+],,test
US20120094979A1,N#Cc1ccccc1O.O=C1CCC(=O)N1I>>N#Cc1cc(I)ccc1O,,CC#N,,O=S(=O)(O)C(F)(F)F,,test
US05736573,CC(N)C(O)c1ccccc1>>CC(N)C(O)c1ccccc1,,O,,Cl,[Na+].[OH-],test
US20160122344A1,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCCCSC)cc1CC2C(C)(C)COC>>COCC(C)(C)C1Cc2cc(OCCCSC)c(OC)cc2-c2cc(=O)c(C(=O)O)cn21,,C1CCOC1,CCO,Cl,[Li+].[OH-],test
US20140105921A1,CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@](C)(O)CO.O=C(CCCCCS(=O)(=O)Cl)OCc1ccccc1>>CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@](C)(O)COS(=O)(=O)CCCCCC(=O)OCc1ccccc1,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20030078258A1,CC(C)(C)OC(=O)N(C[C@@H]1CCc2cc(-c3ccc4c(c3)OC(C)(C)OC4=O)ccc2O1)C[C@@H](COc1ccccc1)O[Si](C)(C)C(C)(C)C.CO>>COC(=O)c1ccc(-c2ccc3c(c2)CC[C@@H](CN(C[C@@H](COc2ccccc2)O[Si](C)(C)C(C)(C)C)C(=O)OC(C)(C)C)O3)cc1O,,CO,,O=C([O-])[O-].[K+].[K+],,test
US06228868B1,CC(=O)CBr.COC(=O)c1ccc(C)nc1>>COC(=O)c1ccc(C)[n+](CC(C)=O)c1.[Br-],,CC(C)=O,,,,test
US20110105462A1,CCN.Cc1ccc(S(=O)(=O)OCC2COc3ccc(OS(C)(=O)=O)cc3O2)cc1>>CCNCC1COc2ccc(OS(C)(=O)=O)cc2O1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140045823A1,CC(C)(C)OC(=O)N1CCC(NC2CC2)CC1.O=C(Cl)c1cnc(Cl)cn1>>CC(C)(C)OC(=O)N1CCC(N(C(=O)c2cnc(Cl)cn2)C2CC2)CC1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20130331378A1,C[Si](C)(C)c1cccc2cc(-c3ccccc3)nn12.O=C1CCC(=O)N1Br>>C[Si](C)(C)c1cccc2c(Br)c(-c3ccccc3)nn12,,O,,CC#N,,test
US20080171743A1,CC#N.CC#N.CO.COCCOC.COCCOC>>C1CCOC1.C1CCOC1,,ClCCl,ClCCl,CO,,test
US20140024650A1,CCOC(=O)[C@@H]1CC(F)(F)CC[C@H]1NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H]1CCC(F)(F)C[C@H]1CO,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20040199014A1,CN.CON.O=C1c2ccccc2OC1(Cl)Cl>>CNC(=O)/C(=N\OC)c1ccccc1O,,COC(C)(C)C,O,Cl,CC(=O)[O-].[Na+],test
US20090209553A1,O=C1CNCC2(CCCCC2)N1c1ccc2[nH]ncc2c1>>c1cc2[nH]ncc2cc1N1CCNCC12CCCCC2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150252030A1,COC(=O)CBr.Cc1cc(O)nc(C)n1>>COC(=O)COc1cc(C)nc(C)n1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080194535A1,O=C(N[C@@H](Cc1cc(Cl)cc(Cl)c1)[C@H](O)CBr)OCc1ccccc1>>O=C(N[C@@H](Cc1cc(Cl)cc(Cl)c1)[C@H]1CO1)OCc1ccccc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20150210677A1,NC1=C(O)C(=O)C(c2ccc(Cl)cc2)O1.O=S(=O)(Cl)c1ccccc1>>NC1=C(OS(=O)(=O)c2ccccc2)C(=O)C(c2ccc(Cl)cc2)O1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20140315886A1,Fc1cccc(-c2ccc3nc(-c4cccnc4)nc(Cl)c3c2)c1.NCCC(=O)O>>O=C(O)CCNc1nc(-c2cccnc2)nc2ccc(-c3cccc(F)c3)cc12,,CC(C)CCO,,CCN(C(C)C)C(C)C,O=C([O-])[O-].[K+].[K+],test
US20030199422A1,CC(C)CCCC(C)CCO.COC(=O)c1ccc(N)cc1>>CC(C)CCCC(C)CCOC(=O)c1ccc(N)cc1,,Cc1ccccc1,,CO,,test
US20010031870A1,C=CCN(C(=O)c1cc(Cl)cc(OCCCO)c1)C1CCCC1.O=C1c2ccccc2C(=O)N1O>>C=CCN(C(=O)c1cc(Cl)cc(OCCCON2C(=O)c3ccccc3C2=O)c1)C1CCCC1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05753679,O=C(Cl)c1ccccc1F.OC1CCN(Cc2ccccc2)CC1>>O=C(OC1CCN(Cc2ccccc2)CC1)c1ccccc1F,,Cc1ccccc1,,CCN(CC)CC,,test
US20100099718A1,N#Cc1ccc(N)nc1.[N-]=[N+]=[N-].[NH4+]>>N.Nc1ccc(-c2nn[nH]n2)cn1,,CN(C)C=O,,[Cl-].[Na+],,test
US20070099901A1,CCOCc1nc2c(N)nc3ccccc3c2n1CCCC(C)=O.CON.Cl>>CCOCc1nc2c(N)nc3ccccc3c2n1CCCC(C)=NOC.Cl,,CCOCC,,CCO,Cl,test
US20150289512A1,CNc1ncccc1N.COC(=N)C(Cl)(Cl)Cl>>Cn1c(C(Cl)(Cl)Cl)nc2cccnc21,,CC(=O)O,,,,test
US20110150827A1,Brc1csc2c(Br)csc12.COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)[nH]1)C(C)C>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc(-c2ccc(-c3csc4c(Br)csc34)cc2)c[nH]1)C(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US04366331,C=CCBr.CC(C)(C)c1cccc(C(C)(C)C)c1O>>C=CCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1,,Cc1ccccc1,,O,[Na+].[OH-],test
US20090131659A1,CC(=O)c1csc(-c2ccc(Cl)c(Cl)c2)c1O.NNC(=O)c1ccc(C(=O)NN2CCOCC2)s1>>CC(=NNC(=O)c1ccc(C(=O)NN2CCOCC2)s1)c1csc(-c2ccc(Cl)c(Cl)c2)c1O,,CS(C)=O,,O,,test
US20020052376A1,O=C(CBr)c1nccs1.c1c[nH]cn1>>O=C(Cn1ccnc1)c1nccs1,,CC#N,,,,test
US20050014813A1,CCI.CCOC(=O)CCc1cn(C(=O)OCc2ccccc2)nc1O>>CCOC(=O)CCc1cn(C(=O)OCc2ccccc2)nc1OCC,,CCOC(C)=O,CN(C)C=O,Cl,O=C([O-])[O-].[K+].[K+],test
US20150342951A1,CC(C)(C)OC(=O)N1CC2CC1CN2.O=C(O)c1cccc(-c2ncnc3ccc(Br)cc23)c1>>CC(C)(C)OC(=O)N1CC2CC1CN2C(=O)c1cccc(-c2ncnc3ccc(Br)cc23)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06124283,CCOc1ccccc1C(=O)Cl.CN1CCN(c2cccc3c2C[C@H](N)CC3)CC1>>CCOc1ccccc1C(=O)N[C@@H]1CCc2cccc(N3CCN(C)CC3)c2C1,,ClCCl,,CCN(CC)CC,,test
US20040053908A1,Cc1ccc(S(=O)(=O)OC[C@H]2CO2)cc1.N#Cc1cc2c(Oc3ccc(N)c(F)c3)ccnc2cc1O>>N#Cc1cc2c(Oc3ccc(N)c(F)c3)ccnc2cc1OC[C@H]1CO1,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140066622A1,C1CNC1.Cc1ccc(-c2c(-c3nc(C)n4ncnc(-n5cncn5)c34)cnn2C)cc1>>Cc1ccc(-c2c(-c3nc(C)n4ncnc(N5CCC5)c34)cnn2C)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160145204A1,CCCCC=CCCc1ccccc1C>>CCCCCCCCc1ccccc1C,[Pd],CCOC(C)=O,,,,test
US04369321,CCCCNC1CC(C)(C)NC(C)(C)C1.CCOC(=O)Cl>>CCCCN(C(=O)OCC)C1CC(C)(C)NC(C)(C)C1,,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20050090526A1,C1CCNCC1.COc1cccc(C(=O)c2ccc(OC)cc2S)c1.N#CCC#N>>COc1cccc(C2c3ccc(OC)cc3SC(=N)C2(C#N)C#N)c1,,CCO,,,,test
US20060205718A1,CC(C)(C)OC(=O)N1CCC(N)CC1.COC(=O)c1cccc2nc(Cl)oc12>>COC(=O)c1cccc2nc(NC3CCN(C(=O)OC(C)(C)C)CC3)oc12,,CC#N,,CCN(CC)CC,,test
US20040132727A1,COc1cc2nccc(Oc3ccc(N)c(C)c3C)c2cc1OC.NN1CCCCC1.S=C(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=S)NN4CCCCC4)c(C)c3C)c2cc1OC,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,,test
US20100160311A1,COc1cc(F)c(-c2c(Cl)nc3ncnn3c2N2CCC(C)CC2)c(F)c1>>CC1CCN(c2c(-c3c(F)cc(O)cc3F)c(Cl)nc3ncnn23)CC1,,Cc1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120101105A1,CC(C)(C)OC(=O)CBr.C[C@@H](NC(=O)[C@H]1C[C@@H]1c1ccc(O)cc1)c1ccc(OCC(F)(F)F)cn1>>C[C@@H](NC(=O)[C@H]1C[C@@H]1c1ccc(OCC(=O)OC(C)(C)C)cc1)c1ccc(OCC(F)(F)F)cn1,,ClCCl,,O,O=C([O-])[O-].[K+].[K+],test
US05380735,C1CCOC1.Cc1cc(Br)c2nc(S)sc2c1>>CCCCSc1nc2c(Br)cc(C)cc2s1,,C1CCOC1,,[H-].[Na+],,test
US20100075965A1,Cc1ccc(S(=O)(=O)/N=c2/ccc(Br)cn2CC(N)=O)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1cn2cc(Br)ccc2n1)C(F)(F)F,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090270389A1,CC(C)(C)[Si](C)(C)Cl.CSc1ncc(C#N)c(N[C@H]2CC[C@H](O)C2)n1>>CSc1ncc(C#N)c(N[C@H]2CC[C@H](O[Si](C)(C)C(C)(C)C)C2)n1,,CN(C)C=O,,c1c[nH]cn1,,test
US05536725,FC1(F)Oc2c(CC3CCC4(CC3)OCCO4)cccc2C1(F)F>>FC1(F)Oc2c(C=C3CCC4(CC3)OCCO4)cccc2C1(F)F,[Pd],CCO,,,,test
US20150025105A1,O=C(C#Cc1ccccc1)c1ccccc1.c1cc[nH+]cc1>>c1ccn2cccc2c1,,CS(C)=O,,[H-].[Na+],,test
US20030069428A1,CC(=O)OC1CC(N2C(=O)c3cccc([N+](=O)[O-])c3C2=O)C(=O)NC1=O.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(=O)OC1CC(N2C(=O)c3cccc([N+](=O)[O-])c3C2=O)C(=O)N(C(=O)OC(C)(C)C)C1=O,CN(C)c1ccncc1,C1COCCO1,,,,test
US20080070866A1,CC(C)(C)OC(=O)N1C(C)(C)OC[C@]1(C)c1ncc(-c2ccc(OCCOCCc3ccccc3)c(C(F)(F)F)c2)s1>>C[C@](N)(CO)c1ncc(-c2ccc(OCCOCCc3ccccc3)c(C(F)(F)F)c2)s1,,CC#N,O,,,test
US20100069347A1,Nc1ccc(O)cc1.O=Cc1ccc(I)cc1OCc1ccccc1>>Oc1ccc(/N=C/c2ccc(I)cc2OCc2ccccc2)cc1,,CC(C)O,,,,test
US20090306062A1,Cc1ccc(OC2(C(=O)O)CCOCC2)c([N+](=O)[O-])c1>>Cc1ccc2c(c1)NC(=O)C1(CCOCC1)O2,[Fe],CC(=O)O,O,,,test
US20130116258A1,O=[N+]([O-])c1ccc(S(=O)(=O)CCc2ccncc2)cc1>>Nc1ccc(S(=O)(=O)CCc2ccncc2)cc1,[Pd],CCO,,,,test
US20140005213A1,COc1cc2nc(-c3nnc4ccc([C@@H](N5CC[C@H](NC(=O)OC(C)(C)C)C5)C(F)(F)F)cn34)ccc2cc1F>>COc1cc2nc(-c3nnc4ccc([C@@H](N5CC[C@H](N)C5)C(F)(F)F)cn34)ccc2cc1F,,O=C(O)C(F)(F)F,,,,test
US20120302566A1,COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(B5OC(C)(C)C(C)(C)O5)cccc43)ccc21.Cc1nccnc1Cl>>COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c(-c5nccnc5C)cccc43)ccc21,,C1CCOC1,,,,test
US20120108638A1,CCc1cc(-c2noc(-c3cc(OC)nc(C(CC)CC)c3)n2)cc(C)c1OC[C@@H]1COC(C)(C)O1>>CCc1cc(-c2noc(-c3cc(OC)nc(C(CC)CC)c3)n2)cc(C)c1OC[C@@H](O)CO,,C1COCCO1,Cl,,,test
US20080287475A1,C1COCCN1.COc1cc(Nc2nc(Cl)nc(Cl)c2F)n[nH]1>>COc1cc(Nc2nc(Cl)nc(N3CCOCC3)c2F)n[nH]1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20130331450A1,C#Cc1ccc([N+](=O)[O-])cc1.C1CCOC1.CCOCC>>CCCC#Cc1ccc([N+](=O)[O-])cc1,,CCOCC,,CO,O=C([O-])[O-].[K+].[K+],test
US20060211720A1,CC1(c2ccc(F)c(C=O)c2)OCCO1.Cn1cnc(-c2ccccc2)n1>>Cn1nc(-c2ccccc2)nc1C(O)c1cc(C2(C)OCCO2)ccc1F,,C1CCOC1,,[Li]CCCC,,test
US20130231328A1,CO[C@@H](C[C@H]1CCc2sc3ncnc(OC4CCC(N(C)C(=O)OC(C)(C)C)CC4)c3c21)C(N)=O.Cl>>CNC1CCC(Oc2ncnc3sc4c(c23)[C@@H](C[C@H](OC)C(N)=O)CC4)CC1.Cl,,ClCCl,,,,test
US20080070928A1,CCOC(=O)Cl.Fc1ccc(Oc2cc3nc(-c4ccccn4)[nH]c3cc2C2CCCN2)cc1>>CCOC(=O)N1CCCC1c1cc2[nH]c(-c3ccccn3)nc2cc1Oc1ccc(F)cc1,[Zn],c1ccccc1,,,,test
US20160075711A1,CCCC[Sn](CCCC)(CCCC)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.COC(=O)c1cc(F)ncc1Br>>COC(=O)c1cc(F)ncc1-c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1,,CC#N,O,,,test
US20160002177A1,C[Si](C)(C)CCOCOc1cc(C2=CCOCC2)cc2c(=O)n(COCC[Si](C)(C)C)cnc12>>C[Si](C)(C)CCOCOc1cc(C2CCOCC2)cc2c1NCN(COCC[Si](C)(C)C)C2=O,[Pd],CCOC(C)=O,,,,test
US20110034689A1,Clc1cc(OCc2ccccc2)ccn1.NN>>NNc1cc(OCc2ccccc2)ccn1,,c1ccncc1,,,,test
US20120309738A1,CN(C)CC1CCN(c2cc(N)c([N+](=O)[O-])cc2Cl)C1>>CN(C)CC1CCN(c2cc(N)c(N)cc2Cl)C1,[Ni],CCOC(C)=O,,,,test
US08431695B2,CC(C)(C)OC(=O)NCc1cccc(-c2ccc3c(N)ncnn23)c1.CC1(C)C(=O)C(Br)C(=O)C1Br>>CC(C)(C)OC(=O)NCc1cccc(-c2cc(Br)c3c(N)ncnn23)c1,,C1CCOC1,,,,test
US20020120007A1,COc1ccc(NC(=O)c2ccc(NC(=O)[C@H](Cc3ccccc3)NC(=O)OC(C)(C)C)cc2NC(=O)c2ccc(C(C)(C)C)cc2)cc1.O=C(O)C(F)(F)F>>COc1ccc(NC(=O)c2ccc(NC(=O)[C@@H](N)Cc3ccccc3)cc2NC(=O)c2ccc(C(C)(C)C)cc2)cc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20100261728A1,N#Cc1cc(N)ccc1F.O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCc2ccccc2[C@H]1c1ccc(C(F)(F)F)cc1>>N#Cc1cc(NC(=O)N2CCc3ccccc3[C@H]2c2ccc(C(F)(F)F)cc2)ccc1F,,C1CCOC1,CO,O,[H-].[Na+],test
US20090163512A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1(COc2ccc(Cl)cc2/C=C2\C(=O)Nc3cc(Cl)ccc32)COC1>>CC1(COc2ccc(Cl)cc2/C=C2\C(=O)N(C(=O)OC(C)(C)C)c3cc(Cl)ccc32)COC1,CN(C)c1ccncc1,ClCCl,,,,test
US20040087623A1,Brc1cc(-c2c[nH]nc2-c2ccccn2)ccn1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>Brc1cc(-c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)nc2-c2ccccn2)ccn1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100286390A1,CON(C)C(=O)c1cnn(COCC[Si](C)(C)C)c1.C[Mg]Br>>CC(=O)c1cnn(COCC[Si](C)(C)C)c1,,C1CCOC1,,[Cl-].[NH4+],,test
US20140066459A1,CC(=O)N1c2ccc(Br)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C.COCCn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>COCCn1cc(-c2ccc3c(c2)[C@H](NC(=O)OC(C)C)C[C@H](C)N3C(C)=O)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20130317026A1,CC(C)I.COC(=O)c1cc(Br)cc2[nH]ncc12>>COC(=O)c1cc(Br)cc2c1cnn2C(C)C,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160176916A1,CC(C)(C)OC(=O)COc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O>>O=C(O)COc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110251190A1,NC1=N[C@@]2(CO1)c1cc(OS(=O)(=O)C(F)(F)F)ccc1Oc1c(F)cc(N3CCCC3=O)cc12.OB(O)c1cccnc1>>NC1=N[C@@]2(CO1)c1cc(-c3cccnc3)ccc1Oc1c(F)cc(N3CCCC3=O)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20040054172A1,CCCCCC.CO.ClCCl.NC(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F.O.O>>O=C(NOC[C@H](O)CO)c1ccc(F)c(F)c1Nc1ccc(I)cc1F,,O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120196377A1,CO.Cc1c(CC(=O)O)c(=O)oc2cc(N)ccc12>>COC(=O)Cc1c(C)c2ccc(N)cc2oc1=O,O=S(=O)(O)O,,,,,test
US20120122863A1,CCC[C@H](C(=O)OC)n1c(=O)c2ccccc2n(Cc2cn(C)c3cc(C)cc(C)c23)c1=O>>CCC[C@H](C(=O)O)n1c(=O)c2ccccc2n(Cc2cn(C)c3cc(C)cc(C)c23)c1=O,,C1COCCO1,O,[Li+].[OH-],,test
US04837225,CC(=O)NCCn1c(C)ccc1C>>Cc1ccc(C)n1CCN,,CCO,,O,[K+].[OH-],test
US20150266857A1,C1CNCCN1.O=S(=O)(c1ccccc1)n1cc(-c2ccc3oc(CCl)nc3c2)c2ccc(F)cc21>>O=S(=O)(c1ccccc1)n1cc(-c2ccc3oc(CN4CCNCC4)nc3c2)c2ccc(F)cc21,,CCOC(C)=O,CN(C)C=O,,,test
US20100087418A1,C=CB1OC(C)(C)C(C)(C)O1.CC(C)(C)OC(=O)N1CCOc2c(Br)cccc2C1>>C=Cc1cccc2c1OCCN(C(=O)OC(C)(C)C)C2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US04529548,CS[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C.O=C(OO)c1cccc(Cl)c1>>CS(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C,,ClC(Cl)Cl,,,,test
US20090137568A1,NC1CCN(CC2Cn3c(=O)ccc4ncc(F)c2c43)CC1.O=C(Cl)c1ccc(Br)cc1>>O=C(NC1CCN(C[C@H]2Cn3c(=O)ccc4ncc(F)c2c43)CC1)c1ccc(Br)cc1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US08569495B2,CCOC(=O)C1(C)CCN(c2ccc(C(C)(C)C)cc2)CC1>>CC1(C(=O)O)CCN(c2ccc(C(C)(C)C)cc2)CC1,,CO,,[Na+].[OH-],,test
US20070185140A1,Clc1nc(-n2cnc3ccccc32)c2nc[nH]c2n1.OC[C@H]1CCCN1>>OC[C@H]1CCCN1c1nc(-n2cnc3ccccc32)c2nc[nH]c2n1,,CS(C)=O,,,,test
US20090069384A1,CCOC(=O)c1cc2sc(Br)cc2n1Cc1cccc(Br)c1.C[Sn](C)(C)C#Cc1ccccc1.Cc1ccccc1>>CCOC(=O)c1cc2sc(C#Cc3ccccc3)cc2n1Cc1ccc(C#Cc2ccccc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20150266824A1,C1CO1.Clc1cncc(Cl)c1>>OCCc1c(Cl)cncc1Cl,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20110092479A1,C[Si](C)(C)CCOCCl.O=[N+]([O-])c1cnc2[nH]nc(Br)c2c1>>C[Si](C)(C)CCOCn1nc(Br)c2cc([N+](=O)[O-])cnc21,,CN(C)C=O,,[H-].[Na+],,test
US20110218248A1,CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1.Cl.O=C(O)CC(=O)O>>CCCCCCCCc1ccc(CCC(N)(CO)CO)cc1.Cl.O=C([O-])CC(=O)[O-],,CCOC(C)=O,,,,test
US20120329780A1,CN1CCN(c2ccc(N)cn2)CC1.COc1ccc(Cn2cc3nc(-c4ccsc4)nc(Cl)c3n2)cc1>>CN1CCN(c2ccc(Nc3nc(-c4ccsc4)nc4cn[nH]c34)cn2)CC1,C1COCCO1,CO,,Cl,,test
US04833259,CC1(C)COC(=O)C1O.COc1ccc(C=CC(=O)Cl)cc1>>COc1ccc(C=CC(=O)O)cc1,,ClCCl,,c1ccncc1,,test
US20030144267A1,CC(C)(C)C1C(O)CCN1C(=O)O.Clc1ccc(CBr)cc1>>CC(C)(C)OC(=O)N1CCC(OCc2ccc(Cl)cc2)C1,,C1CCOC1,,[H-].[Na+],,test
US20060105997A1,Br[Mg]C1CC1.CC(C)(C)OC(=O)N1CC(OS(=O)(=O)C(F)(F)F)=C[C@H]1c1ccccc1>>CC(C)(C)OC(=O)N1CC(C2CC2)=C[C@H]1c1ccccc1,I[Cu]I,C1CCOC1,,,,test
US20140315220A1,CN(Cc1ccccc1B(O)O)Cc1c2ccccc2c(CN(C)C(=O)c2ccc(C(=O)N(C)Cc3c4ccccc4c(CN(C)Cc4ccccc4B(O)O)c4ccccc34)c(OCc3cn(CCCNC(=O)OC(C)(C)C)nn3)c2)c2ccccc12>>CN(Cc1ccccc1B(O)O)Cc1c2ccccc2c(CN(C)C(=O)c2ccc(C(=O)N(C)Cc3c4ccccc4c(CN(C)Cc4ccccc4B(O)O)c4ccccc34)c(OCc3cn(CCCN)nn3)c2)c2ccccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090111871A1,CC#N.O=C=NS(=O)(=O)Cl.OCC(CO)c1ccccc1>>NC(=O)OCC(COC(N)=O)c1ccccc1,,Cc1ccccc1,,O,,test
US20160184318A1,Cc1nnn(Cc2cc(C(F)(F)F)ccc2/C=C/C(=O)O)n1.FC(F)(F)C1COCCN1>>Cc1nnn(Cc2cc(C(F)(F)F)ccc2/C=C/C(=O)N2CCOCC2C(F)(F)F)n1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20060148858A1,CCOC(=O)C(C)(C)Oc1cccc(O)c1.CCOc1nn(-c2ccccn2)cc1CCCO>>CCOc1nn(-c2ccccn2)cc1CCCOc1cccc(OC(C)(C)C(=O)O)c1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20100160302A1,CC1(C23CC4CC2CC(COS(C)(=O)=O)(C4)C3)OCCO1.c1nc[nH]n1>>CC1(C23CC4CC2CC(Cn2cncn2)(C4)C3)OCCO1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US07381841B2,COC(=O)c1cc(S(C)(=O)=O)c(Br)cc1C.FS(F)(F)(F)(F)c1ccc(S)cc1>>COC(=O)c1cc(S(C)(=O)=O)c(Sc2ccc(S(F)(F)(F)(F)F)cc2)cc1C,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120277192A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cc1cc(Br)cc(Nc2nccc(C(C)C)n2)c1>>Cc1cc(Nc2nccc(C(C)C)n2)cc(B2OC(C)(C)C(C)(C)O2)c1,,CS(C)=O,,CC(=O)[O-].[K+],,test
US20120065195A1,CI.O=C1NC(=O)C2(CCCc3ccc(Br)cc32)N1>>CN1C(=O)NC2(CCCc3ccc(Br)cc32)C1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04677129,C#CCBr.O=C1NC(=O)C2(c3ccc([N+](=O)[O-])cc3)CC1C2>>C#CCN1C(=O)C2CC(c3ccc([N+](=O)[O-])cc3)(C2)C1=O,,CN(C)C=O,,[H-].[Na+],,test
US20130137661A1,CC(C)(C)OC(=O)N[C@@H](CO)c1ccccc1.Cc1c(Br)c(=O)[nH]c(=O)n1Cc1c(F)cccc1F>>Cc1c(Br)c(=O)n(C[C@H](NC(=O)OC(C)(C)C)c2ccccc2)c(=O)n1Cc1c(F)cccc1F,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04497817,CC(Br)C(=O)c1ccccc1.Nc1nc2ccccc2s1>>Cc1c(-c2ccccc2)nc2sc3ccccc3n12,,CC#N,,,,test
US20080004327A1,CO.O=C(O)c1cc2sccc2[nH]1>>COC(=O)c1cc2sccc2[nH]1,,CO,,C[Si](C)(C)C=[N+]=[N-],,test
US20070043061A1,COc1cc(C(=O)Cn2c(-c3nonc3N)nc3ccccc32)ccc1OCc1ccccc1>>COc1cc(C(=O)Cn2c(-c3nonc3N)nc3ccccc32)ccc1O,[Pd],C1CCOC1,,,,test
US20090124624A1,NCCN1CCCCC1.O=C(Cl)c1ccc(CCl)cc1>>O=C(NCCN1CCCCC1)c1ccc(CCl)cc1,,ClCCl,,CCN(CC)CC,O,test
US20130053409A1,C=CC(=O)Cl.COc1cc(C2=CCN(C)CC2)c(N)cc1Nc1ncc(Cl)c(-c2c[nH]c3ccccc23)n1>>C=CC(=O)Nc1cc(Nc2ncc(Cl)c(-c3c[nH]c4ccccc34)n2)c(OC)cc1C1=CCN(C)CC1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US06262058B1,CCCOc1nc2ccsc2c(=O)n1CCC.O=C1CCC(=O)N1Cl>>CCCOc1nc2c(Cl)scc2c(=O)n1CCC,,c1ccncc1,,,,test
US20100197678A1,Brc1ccc2cc[nH]c2c1.C=CCBr>>C=CCn1ccc2ccc(Br)cc21,,CN(C)C=O,,[H][H],[H-].[Na+],test
US05484763,CC1=C(C)C(=O)OC1=O.COC(=O)C(C)c1noc2cc(F)c(N)cc12>>COC(=O)C(C)c1noc2cc(F)c(N3C(=O)C(C)=C(C)C3=O)cc12,,CC(=O)O,,,,test
US20020099047A1,COc1ccc(CCOS(=O)(=O)c2ccc(C)cc2)cc1.O=C(O[C@H]1CCNC1)c1ccc([N+](=O)[O-])cc1>>COc1ccc(CCN2CC[C@H](OC(=O)c3ccc([N+](=O)[O-])cc3)C2)cc1,,CC#N,,[I-].[Na+],,test
US20100105714A1,C#CC1(O[Si](C)(C)C)CCC2(CC1)OCCO2.O=Cc1ccc2ncnn2c1>>C[Si](C)(C)OC1(C#CC(O)c2ccc3ncnn3c2)CCC2(CC1)OCCO2,,C1CCOC1,CCCCCC,CC(C)NC(C)C,[Li]CCCC,test
US04816452,CCOC(=O)/C(=N\O[C@@H]1CC[C@H](Cl)CC1)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>CCOC(=O)/C(=N\O[C@@H]1CC[C@H](Cl)CC1)c1csc(N)n1,,O=CO,,,,test
US20150291593A1,CC(N)c1cn2ccc(Cl)c2c(=O)n1-c1cccc(F)c1.Clc1ncnc2[nH]cnc12>>CC(Nc1ncnc2[nH]cnc12)c1cn2ccc(Cl)c2c(=O)n1-c1cccc(F)c1,,CCCCO,,,,test
US04612314,CCCCCCCC(=O)Cl.CN(C)c1ccncc1.COc1ccc(C(Nc2nc3c(ncn3COC(CO)CO)c(=O)[nH]2)(c2ccccc2)c2ccccc2)cc1.N#N.O.c1ccncc1>>CCCCCCCC(=O)OCC(COC(=O)CCCCCCC)OCn1cnc2c(=O)[nH]c(NC(c3ccccc3)(c3ccccc3)c3ccc(OC)cc3)nc21.N#N,CN(C)c1ccncc1,ClCCl,c1ccncc1,,,test
US20080119491A1,COc1ccc(CNc2nccnc2C(Cl)=NO)cc1.Nc1cccc(C(F)(F)F)c1>>COc1ccc(CNc2nccnc2C(=NO)Nc2cccc(C(F)(F)F)c2)cc1,,CCO,,CCN(C(C)C)C(C)C,,test
US20090221555A1,N#Cc1ccc([N+](=O)[O-])cc1N1CCNC1C1OCCO1>>N#Cc1ccc(N)cc1-n1ccnc1C1OCCO1,[Pd],CCO,,,,test
US20080261987A1,Cc1[nH]nc(N)c1Cl.O=C(CCl)N1CCN(c2ccc(F)cc2)CC1>>Cc1c(Cl)c(N)nn1CC(=O)N1CCN(c2ccc(F)cc2)CC1,,CCCCCC,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100160288A1,NCC1CCOCC1.Nc1c(Cl)ncnc1Cl>>Nc1c(Cl)ncnc1NCC1CCOCC1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20160083387A1,C=C1C=C[C@H]2[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H]([C@@]3(C)CC[C@H](O[Si](C)(C)C(C)(C)C)C[C@@H]3CO[Si](C)(C)C(C)(C)C)CC[C@]12C>>C=C1C=C[C@H]2[C@H](CO)[C@@H]([C@@]3(C)CC[C@H](O)C[C@@H]3CO)CC[C@]12C,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04689341,CN1C=C[NH+](CC(=O)c2ccc(NS(C)(=O)=O)cc2)C1.[Cl-]>>CN1C=C[NH+](CC(O)c2ccc(NS(C)(=O)=O)cc2)C1.[Cl-],[Pd],O,,,,test
US20050014811A1,COCCNC(=O)Nc1nc2ccc(O)cc2[nH]1.O=C(Oc1ccc(S(=O)(=O)Cl)cc1)c1ccccc1>>COCCNC(=O)Nc1nc2cc(OS(=O)(=O)c3ccc(OC(=O)c4ccccc4)cc3)ccc2[nH]1,,CC(C)=O,,CCN(CC)CC,,test
US20110184177A1,CCOC(=O)C(C)(CC)NC(=O)c1cc(Cl)c2ccccc2c1OCC1CCN(C(=O)OC(C)(C)C)CC1>>CCC(C)(NC(=O)c1cc(Cl)c2ccccc2c1OCC1CCN(C(=O)OC(C)(C)C)CC1)C(=O)O,,C1CCOC1,,CO,[Na+].[OH-],test
US20090105219A1,COC(=O)Cn1c(=O)n(Cc2ccc3cc4c(cc3n2)C[C@]2(C4)C(=O)Nc3ncccc32)c2cccc([N+](=O)[O-])c21>>O=C1Cn2c(=O)n(Cc3ccc4cc5c(cc4n3)C[C@]3(C5)C(=O)Nc4ncccc43)c3cccc(c32)N1,[Fe],CC(=O)O,,,,test
US05003080,CCOC(CCn1c(-c2ccc(F)cc2)c(-c2ccccc2)c(C(=O)Nc2ccccc2)c1C(C)C)OCC>>CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CCC=O,,CC(C)=O,,Cl,,test
US20130109713A1,CC(C)(C)OC(=O)NC(=NS(=O)(=O)C(F)(F)F)NC(=O)OC(C)(C)C.CCN(CC)CC.COc1cc(C(F)(F)F)ccc1-c1cccc2c(CCN)cccc12>>CCCCCC.CCOC(C)=O,,ClCCl,,,,test
US20160115333A1,CC(C)(C)OC(=O)/C=C/C(=O)OC(C)(C)C.CCCCOC(=O)/C=C/C(=O)OCCCC>>CC(C)(C)OC(=O)/C=C/C(=O)OC(C)(C)C.CCCCOC(=O)/C=C/C(=O)OCCCC,,O,,,,test
US20110281886A1,CCNCCNC(=O)C(F)(F)F.O=C1CCC(=O)N1C(=O)OCc1ccccc1>>CCN(CCNC(=O)C(F)(F)F)C(=O)OCc1ccccc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20160090374A1,CC(=O)Cl.COc1cc2nc(Cl)nc(N3CCC[C@@H](N)C3)c2cc1OC>>COc1cc2nc(Cl)nc(N3CCC[C@@H](NC(C)=O)C3)c2cc1OC,,ClCCl,,CCN(CC)CC,,test
US20040082607A1,CCCCOc1c(CNC(=O)OCC2c3ccccc3-c3ccccc32)n(CC(C)C)c(=O)c2ccc(C(N)=S)cc12.CCOC(=O)C(=O)CBr>>CCCCOc1c(CNC(=O)OCC2c3ccccc3-c3ccccc32)n(CC(C)C)c(=O)c2ccc(-c3nc(C(=O)OCC)cs3)cc12,,CCO,,O,,test
US20040122050A1,CS(=O)(=O)Cl.O=S(=O)(CC1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CC(O)C1>>CS(=O)(=O)OC1CN(S(=O)(=O)CC2CCC(c3cc(F)ccc3F)(S(=O)(=O)c3ccc(Cl)cc3)CC2)C1,,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US20070105943A1,C=C[Sn](CCCC)(CCCC)CCCC.COC(=O)c1ccc(Cl)nc1N>>C=Cc1ccc(C(=O)OC)c(N)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1C,,CCOC(C)=O,O,test
US20090124604A1,CCOC(OCC)OCC.COC(=O)c1cc(Br)ccc1N.COC(=O)c1ccc(C)c(N)c1>>COC(=O)c1ccc(C)c(-n2cnc3ccc(Br)cc3c2=O)c1,,Cc1ccccc1,,CC(=O)O,,test
US05948793,CC(C)(C)OC(=O)N1CCC[C@H]1CO.Cc1ncccc1O>>Cc1ncccc1OC[C@@H]1CCCN1C(=O)OC(C)(C)C,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140296183A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCCCCCCOc1ccc(CCC(C)(N)CO)cc1C(F)(F)F>>CCCCCCCOc1ccc(CCC(C)(CO)NC(=O)OC(C)(C)C)cc1C(F)(F)F,,CO,,CCN(C(C)C)C(C)C,Cl,test
US20090253677A1,CCOC(=O)c1nc2n(c(=O)c1OCc1ccccc1)CC1CCC2(OCCO)CC1.CI>>COCCOC12CCC(CC1)Cn1c2nc(C(=O)OC)c(OCc2ccccc2)c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20080132495A1,COc1cc2nc(-c3n[nH]cc3NC(=O)C3CN(C(=O)OC(C)(C)C)CCO3)[nH]c2cc1OC.O=C(O)C(F)(F)F>>COc1cc2nc(-c3n[nH]cc3NC(=O)C3CNCCO3)[nH]c2cc1OC.O=C(O)C(F)(F)F,,ClCCl,,COc1ccccc1,,test
US20100069383A1,CCOc1ccc(NC)cc1F.Cc1nc(Cl)c2cc(Br)ccc2n1>>CCOc1ccc(N(C)c2nc(C)nc3ccc(Br)cc23)cc1F,,CC(C)O,,,,test
US20100004312A1,COC(=O)C[C@@H]1COc2cc(O)ccc21.Cc1c(C)c(-c2cccc(CO)c2)c(C)c(C)c1OCCCS(C)(=O)=O>>COC(=O)C[C@@H]1COc2cc(OCc3cccc(-c4c(C)c(C)c(OCCCS(C)(=O)=O)c(C)c4C)c3)ccc21,,CCCCCC,Cc1ccccc1,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20140163012A1,CC(C)(C)OC(=O)N1CCCc2oc3cc(-n4ccc(OCc5ccccc5)cc4=O)ccc3c2C1>>O=c1cc(OCc2ccccc2)ccn1-c1ccc2c3c(oc2c1)CCCNC3,,CCOCC,CO,Cl,O=C([O-])O.[Na+],test
US20120244171A1,CC(C)(S)CSCc1cc(CO)cc(CO)c1.CSS(C)(=O)=O>>CSSC(C)(C)CSCc1cc(CO)cc(CO)c1,,CCO,ClCCl,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20090306062A1,COCCCN1CCOc2ccc(CO[C@@H]3CC[C@@H](CC(C)(C)C(=O)OC)N(S(=O)(=O)c4ccc(C)cc4)C3)cc21>>COCCCN1CCOc2ccc(CO[C@@H]3CC[C@@H](CC(C)(C)C(=O)O)N(S(=O)(=O)c4ccc(C)cc4)C3)cc21,,C1CCOC1,CO,[Na+].[OH-],,test
US20090253687A1,Cc1cc(F)ccc1N.O=N[O-]>>Cc1cc(F)ccc1NN,,Cl,,Cl[Sn]Cl,,test
US20140323484A1,COc1cc(CCN(CC2CCN(C(=O)OC(C)(C)C)CC2)C(=O)OC(C)(C)C)c(Cl)cc1NC(=O)Nc1cnc(C#N)cn1.Cl>>COc1cc(CCNCC2CCNCC2)c(Cl)cc1NC(=O)Nc1cnc(C#N)cn1.Cl,,C1COCCO1,CC#N,,,test
US04335127,O=CNc1cc(F)ccc1C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1>>Nc1cc(F)ccc1C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1,,CCO,,O=S(=O)(O)O,[Na+].[OH-],test
US20020091264A1,CCNc1nc(CCO)cs1.CCOC(=O)CC1Cc2ccc(O)cc2Cc2ccccc21>>CCNc1nc(CCOc2ccc3c(c2)Cc2ccccc2C(CC(=O)OCC)C3)cs1,,CN(C)C=O,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040235810A1,CC#C[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@@H](c3ccc(N(C)CCO[C@H]4CC[C@]5(C)[C@H]6C[C@H](O)[C@]7(C)[C@@H]([C@H](C)CC(C)C(=O)O)CC[C@H]7[C@@H]6[C@H](OCSC)C[C@@H]5C4)cc3)C[C@@]21C.O=S(=O)(Cl)Cl>>CC#C[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@@H](c3ccc(N(C)CCO[C@H]4CC[C@]5(C)[C@H]6C[C@H](O)[C@]7(C)[C@@H]([C@H](C)CC(C)C(=O)O)CC[C@H]7[C@@H]6[C@H](OCCl)C[C@@H]5C4)cc3)C[C@@]21C,,ClCCl,,,,test
US20100316601A1,CC1=NN(c2ccc3c(c2)CCO3)C(=O)C1.Nc1cc(F)cc(-c2cccc(C(=O)O)c2)c1O.O=N[O-]>>CC1=NN(c2ccc3c(c2)CCO3)C(=O)C1=NNc1cc(F)cc(-c2cccc(C(=O)O)c2)c1O,,Cl,,O=C([O-])O.[Na+],,test
US20070066618A1,Cc1cc(N)nc(C)c1C#N.O>>Cc1cc(O)nc(C)c1C#N,,O,O=S(=O)(O)O,O=N[O-].[Na+],,test
US20030078251A1,CC(=O)Cl.COc1ccc(CCC(=O)O)cc1NC(=O)C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2N(CC(C)(C)CO)C1=O>>COc1ccc(CCC(=O)O)cc1NC(=O)C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2N(CC(C)(C)COC(C)=O)C1=O,,O,,CCOC(C)=O,c1ccncc1,test
US20130178478A1,CCOC(=O)c1nnc(Cl)cc1Cl.Nc1ccc2c(n1)CCC2>>CCOC(=O)c1nnc(Cl)cc1Nc1ccc2c(n1)CCC2,,CC#N,,CCN(C(C)C)C(C)C,,test
US20010056117A1,COc1ccc(C2(O)CCC3(CC2)OCCO3)c2c1OCCO2.C[Si](C)(C)C#N>>COc1ccc(C2(C#N)CCC3(CC2)OCCO3)c2c1OCCO2,,ClCCl,,O=C([O-])O.[Na+],,test
US05091109,CCCCBr.CCCCCCc1ccc(-c2nnc(-c3ccc4cc(O)ccc4c3)s2)cc1>>CCCCCCc1ccc(-c2nnc(-c3ccc4cc(OCCCC)ccc4c3)s2)cc1,,CCCCO,,[K+].[OH-],,test
US20130158009A1,CCc1cnc(N2CCC(N3CCC[C@H](NC)C3=O)CC2)nc1.CS(=O)(=O)c1cc(F)c(F)cc1F>>CCc1cnc(N2CCC(N3CCC[C@H](N(C)c4cc(F)c(S(C)(=O)=O)cc4F)C3=O)CC2)nc1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20100160309A1,CC(C)c1nc2cc[nH]c(=O)c2c2cc(Br)ccc12.O=C1CCC(=O)N1I>>CC(C)c1nc2c(I)c[nH]c(=O)c2c2cc(Br)ccc12,,CCOC(C)=O,CN(C)C=O,,,test
US04914188,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)O.CN[C@@H](C)C(=O)N[C@@H](C)C(=O)OCc1ccccc1>>CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N(C)[C@@H](C)C(=O)N[C@@H](C)C(=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,O=C1OCCN1P(=O)(Cl)N1CCOC1=O,test
US20100331326A1,Cc1ccncc1N1CCNC1=O.Fc1ccc(Br)cc1>>Cc1ccncc1N1CCN(c2ccc(F)cc2)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=C([O-])[O-].[K+].[K+],test
US20090075979A1,CCNC[C@@H]1CC[C@@H](CC(=O)OCC)CC1.O=Cc1cc(C(F)(F)F)ccc1F>>CCOC(=O)C[C@@H]1CC[C@@H](CN(CC)c2ccc(C(F)(F)F)cc2C=O)CC1,,Cc1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20030144338A1,CCCCCCCCCCCCOc1ccc(CCn2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)OCC)cc2)cc1>>CCCCCCCCCCCCOc1ccc(CCn2c(C)ccc2-c2ccc(O[C@H](Cc3ccccc3)C(=O)O)cc2)cc1,,C1CCOC1,CO,Cl,[K+].[OH-],test
US20160168156A1,CC(C)(C)[S@](=O)N1CCC[C@@H]1c1cc(F)ccc1F>>Fc1ccc(F)c([C@H]2CCCN2)c1,,CO,,Cl,,test
US20120165337A1,CC(C)(C)N1CCN(c2ccc(N3CCN(C(=O)O)c4ccccc43)nc2)CC1>>CC(C)(C)N1CCN(c2ccc(N3CCNc4ccccc43)nc2)CC1,,C1COCCO1,ClCCl,Cl,O=C([O-])O.[Na+],test
US20090149425A1,CC(O)c1cc(C(C)(C)C)on1.Cc1ccc(S(=O)(=O)Cl)cc1>>CC(Cl)c1cc(C(C)(C)C)on1,,c1ccncc1,,O,,test
US20110178063A1,Nc1cc(-c2cccc3[nH]ccc23)cc2nn(C3CCCCO3)cc12.O=C(O)c1c[nH]cn1>>O=C(Nc1cc(-c2cccc3[nH]ccc23)cc2[nH]ncc12)c1c[nH]cn1,,CCN(C(C)C)C(C)C,CN(C)C=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20140349998A1,CCOC(=O)c1c[nH]c2ncnc(-c3cccc([N+](=O)[O-])c3)c12.C[Si](C)(C)CCOCCl>>CCOC(=O)c1cn(COCC[Si](C)(C)C)c2ncnc(-c3cccc([N+](=O)[O-])c3)c12,,C1CCOC1,,[H-].[Na+],,test
US05563162,COCCN(CCOC)C(=O)c1cccc([N+](=O)[O-])c1>>COCCN(CCOC)C(=O)c1cccc(N)c1,[Pd],CCOC(C)=O,,[H][H],,test
US20110312944A1,CC(C)(C)c1cc(NC(=O)C2CCCNC2)no1.ClCc1ccc(Cl)cc1>>CC(C)(C)c1cc(NC(=O)C2CCCN(Cc3ccc(Cl)cc3)C2)no1,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,Cl,test
US20100240702A1,CCOC(=O)CCNc1cc(C(=O)OC(C)(C)C)ccc1[N+](=O)[O-]>>CCOC(=O)CCNc1cc(C(=O)OC(C)(C)C)ccc1N,[Pd],CCO,,,,test
US20140274959A1,CC(C)=C(O)C(O)CO.CCCCCCCCCCCCCCCCCCOCCNc1nc2c(ncn2CCOCP(=O)(O)O)c(=O)[nH]1>>CCCCCCCCCCCCCCCCCCOCCN(CC(O)CO)C1N=c2c(nc(=C(C)C)n2CCOCP(=O)(O)O)C(=O)N1,,CN(C)C=O,Cc1ccccc1,O=C(Cl)C(=O)Cl,O=C([O-])O.[Na+],test
US04788304,OCCCCCOc1ccc(Cl)cc1>>O=CCCCCOc1ccc(Cl)cc1,,CCOCC,ClCCl,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20100075948A1,CC(=O)OC(C)=O.CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCNCC2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F.ClCCl>>CN1CCC(NC(=O)C2NC(CC(C)(C)C)C(C#N)(c3ccc(Cl)cc3F)C2c2cccc(Cl)c2F)CC1=C=O,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20140045690A1,Cc1c(C(=O)Cl)cnn1C(C(F)(F)F)C(F)(F)F.Nc1ccnnc1>>Cc1c(C(=O)Nc2ccnnc2)cnn1C(C(F)(F)F)C(F)(F)F,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20110003738A1,C=CC(C)=O.CCO.CCOC(CCCN)OCC.CN(N)c1cccc(Br)c1>>Cn1c2c(c3ccc(Br)cc31)CN1CCCC1C2,,CCO,CCOCC,Cl,Cl,test
US20150307451A1,COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)c(C)c(C)c1O.Cn1ccc(-c2ccc(CCl)cc2)n1>>COC(=O)c1cc(Cc2ccc(-c3ccn(C)n3)cc2)c(C)c(C)c1O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20060135578A1,COc1cc(COc2nn(Cc3ccccc3)cc2C=O)ccc1OCc1nc(-c2ccco2)oc1C.C[Mg]Br>>COc1cc(COc2nn(Cc3ccccc3)cc2C(C)O)ccc1OCc1nc(-c2ccco2)oc1C,,C1CCOC1,,O,,test
US20090105309A1,BrC(Br)(Br)Br.N#Cc1cccc(COCCOc2ccc(CCO)cc2)c1>>N#Cc1cccc(COCCOc2ccc(CCBr)cc2)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090124613A1,C=CC(O)(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1C1OCCCO1>>C=CC1(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(O)c2ccccc21,,CC(C)=O,O,Cl,,test
US20150344473A1,CC1(C)OB(c2ccc(OC3CCOCC3)c(C#N)c2)OC1(C)C.COc1cc(-c2cc3c(Cl)ncnc3n2COCC[Si](C)(C)C)ccc1N1CCN(C2COC2)CC1>>COc1cc(-c2cc3c(-c4ccc(OC5CCOCC5)c(C#N)c4)ncnc3n2COCC[Si](C)(C)C)ccc1N1CCN(C2COC2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20090082379A1,O=C(c1cccc([N+](=O)[O-])c1)N1CCCC1>>Nc1cccc(C(=O)N2CCCC2)c1,[Pd],CO,,O=C[O-].[NH4+],,test
US20100204196A1,CC(=O)O.COc1ccc(N)c(C)c1>>COc1ccc(NC(C)=O)c(C)c1,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20120077781A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCNCc3ccccc3)c2cc1C>>Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCN(Cc3ccccc3)C(=O)OC(C)(C)C)c2cc1C,,CO,,CCN(CC)CC,,test
US20120202856A1,CCOC(=O)c1cc(C(C)(C)C)nn1CCOCc1ccccc1>>CC(C)(C)c1cc(C(=O)O)n(CCOCc2ccccc2)n1,,C1COCCO1,CO,[Na+].[OH-],,test
US20100144987A1,Cc1cc(C)c(N)c(C)c1.O=CO>>Cc1cc(C)c(NC=O)c(C)c1,,ClCCl,,CC(=O)OC(C)=O,,test
US20130053382A1,CC(C)(C)OC(=O)N1Cc2ccc(-c3cc4cnn(COCC[Si](C)(C)C)c4cc3N)cc2C1.O=C(O)c1csc(-c2cc(C(F)(F)F)nn2C2CCCCO2)n1>>CC(C)(C)OC(=O)N1Cc2ccc(-c3cc4cnn(COCC[Si](C)(C)C)c4cc3NC(=O)c3csc(-c4cc(C(F)(F)F)nn4C4CCCCO4)n3)cc2C1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140329820A1,CNN.O=Cc1c(Br)cncc1Br>>CNN=Cc1c(Br)cncc1Br,,CC(C)O,,,,test
US20150368254A1,CC(=O)O[C@H](C)[C@H](NC(=O)OCc1ccccc1)C(N)=O>>CC(=O)O[C@H](C)[C@H](N)C(N)=O,[Pd],CO,,,,test
US20110245272A1,Clc1cnc2[nH]c3c(c2c1)CN1CCCC1C3.c1cc(C2CO2)ccn1>>OC(Cn1c2c(c3cc(Cl)cnc31)CN1CCCC1C2)c1ccncc1,,CN(C)C=O,,[H-].[Na+],,test
US20150259295A1,CC[C@@H](C)OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)OC)CC4)cc3)cc2)cnn1C>>CC[C@@H](C)OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)cnn1C,,CO,,C1CCOC1,[Na+].[OH-],test
US20150005232A1,CN(C)C(=O)CCl.Cn1cc(Br)c(=O)[nH]c1=O>>CN(C)C(=O)Cn1c(=O)c(Br)cn(C)c1=O,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05405997,CC(C)(F)CCCCBr.CCNCCCC(O)c1ccc(NS(C)(=O)=O)cc1>>CCN(CCCCC(C)(C)F)CCCC(O)c1ccc(NS(C)(=O)=O)cc1,,CC#N,,O=C([O-])O.[Na+],,test
US06867161B1,C=CCC(CCC(=O)Cl)(C(=O)OCC)C(=O)OCC.[Li]C>>C=CCC(CCC(C)=O)(C(=O)OCC)C(=O)OCC,I[Cu]I,CCOCC,,[Cl-].[NH4+],,test
US20130137865A1,CON(C)C(=O)c1cnn(C)c1COc1ccc(C(F)(F)F)cc1.C[Mg]Br>>CC(=O)c1cnn(C)c1COc1ccc(C(F)(F)F)cc1,,O,,C1CCOC1,Cl,test
US20130090327A1,CC(C)(C)OC(=O)N1CC(N)C1.Nc1ccc(Oc2ccnc3cc(-c4ccc(C5OCCO5)cn4)sc23)c(F)c1.O=C(Cl)Oc1ccccc1>>CC(C)(C)OC(=O)N1CC(NC(=O)Nc2ccc(Oc3ccnc4cc(-c5ccc(C6OCCO6)cn5)sc34)c(F)c2)C1,,CN1CCCC1=O,O,c1ccncc1,,test
US20090023724A1,C1COCCO1.CCN(C(C)C)C(C)C.CCOC(=O)CN.CCOC(=O)CNC(=O)Nc1ncc(Br)nc1Br.Nc1ncc(Br)nc1Br.O=C(n1ccnc1)n1ccnc1>>O=C(Cn1c(=O)[nH]c2ncc(-c3ccc(-c4nnc[nH]4)cc3)nc21)N1CCOCC1,,C1COCCO1,O,CN(C)C=O,Cl,test
US06048861,COC(=O)CCCCCCCCc1ccc2cccnc2n1>>COC(=O)CCCCCCCCc1ccc2c(n1)NCCC2,[Pd],CCO,,,,test
US20040220173A1,COc1cccc2c(C3CCN(C(=O)OC(C)(C)C)CC3)noc12.Cl>>COc1cccc2c(C3CCNCC3)noc12.Cl,,CCOCC,,CO,,test
US20030232848A1,CC(=O)OCCBr.COCN(c1[nH]nc(OC)c1-c1ccc2c(c1)OCO2)S(=O)(=O)CCc1ccccc1>>COCN(c1nn(CCOC(C)=O)c(OC)c1-c1ccc2c(c1)OCO2)S(=O)(=O)CCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20050245554A1,COc1nc(S(C)(=O)=O)nc(-c2ccc(Cl)cc2Cl)c1S(=O)(=O)C(F)(F)F.Oc1ccc(F)c(F)c1>>COc1nc(Oc2ccc(F)c(F)c2)nc(-c2ccc(Cl)cc2Cl)c1S(=O)(=O)C(F)(F)F,,C1CCOC1,ClCCl,[Li]CCCC,[Cl-].[NH4+],test
US20140274690A1,CC(C)(C)OC(=O)N(N)c1cccs1.O=C(Cl)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)N(NC(=O)c1ccc(Cl)cc1)c1cccs1,,C1CCOC1,,CCN(CC)CC,,test
US05670503,O=C(C(=O)N1NCCn2nc(-c3ccc(F)cc3)c(-c3ccncc3)c21)c1ccccc1.O=S(=O)(O)O>>O=C(C(=O)N1NCCn2nc(-c3ccc(F)cc3)c(-c3ccncc3)c21)c1ccccc1.O=S(=O)(O)O,,CCO,CCOC(C)=O,,,test
US20060223810A1,CN(C)c1ccc(C=O)c(F)c1C#N.COc1ccc2nccc(-n3cc4c(n3)CCC(N)C4)c2n1>>COc1ccc2nccc(-n3cc4c(n3)CCC(NCc3ccc(N(C)C)c(C#N)c3F)C4)c2n1,O,CO,,[BH4-].[Na+],,test
US04859229,CC(C)Oc1cc(N=C=O)c(F)cc1Cl.CCOC(=O)/C(F)=C(/C)N>>Cc1[nH]c(=O)n(-c2cc(OC(C)C)c(Cl)cc2F)c(=O)c1F,,CCOCC,,,,test
US04661513,COCCOc1ccc(OCC2CO2)cc1.NCCNC(=O)C1CCCOC1>>COCCc1ccc(OCC(O)CNCCNC(=O)C2CCCOC2)cc1,,CCOC(C)=O,,CO,,test
US05663448,CC(=O)Nc1ccc(C(C)(C)C)cc1Br.Cl>>CC(C)(C)c1ccc(N)c(Br)c1.Cl,,CCO,,,,test
US05624935,CCO.CNc1nc(Cl)ccc1[N+](=O)[O-]>>CCOc1ccc([N+](=O)[O-])c(NC)n1,,CN(C)C=O,,[H-].[Na+],,test
US20080300231A1,CC(C)(C)OC(=O)N[C@@H](CCCO)C(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N[C@@H](CCCOS(C)(=O)=O)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,O,test
US20050137139A1,CCCC(NC(=O)OCc1ccccc1)C(O)C(=O)NC1CC1>>CCCC(N)C(O)C(=O)NC1CC1,,CO,,,,test
US20090131458A1,CCCCCNc1nc(N)c2ncn(C3CCCCO3)c2n1.O=C1CCC(=O)N1Br>>CCCCCNc1nc(N)c2nc(Br)n(C3CCCCO3)c2n1,,ClC(Cl)Cl,ClCCl,,,test
US04310682,Cc1ccccc1NC(=O)c1ccccc1O.II>>Cc1ccccc1NC(=O)c1cc(I)ccc1O,,CC(=O)O,,,,test
US20020006932A1,CN1C(=O)C(c2ccccc2)C2(CCN(Cc3ccccc3)CC2)C1=O>>CN1CC(c2ccccc2)C2(CCN(Cc3ccccc3)CC2)C1,,O,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20090137609A1,CC(=O)c1ccc(Br)cc1.[Li]C>>CC(C)(O)c1ccc(Br)cc1,,C1CCOC1,,[Cl-].[NH4+],,test
US20040142979A1,O=C(NOC1CCCCO1)C1(S(=O)(=O)c2ccc(-c3ccc(OC(F)(F)C(F)F)cc3)s2)CCOCC1>>O=C(NO)C1(S(=O)(=O)c2ccc(-c3ccc(OC(F)(F)C(F)F)cc3)s2)CCOCC1,,C1COCCO1,,CO,Cl,test
US05856518,CCOC(=O)C1(C=O)CC1.CC[C@H](N)c1ccccc1.[C-]#N>>CCOC(=O)C1(C(C#N)N[C@@H](CC)c2ccccc2)CC1,,CCO,O,Cl,,test
US04840953,CCOC(=O)CC(C)=O.Nc1ncccc1O>>Cc1cc(=O)n2cccc(O)c2n1,,ClC(Cl)Cl,,[Na+].[OH-],,test
US20050256191A1,COC(=O)c1cc(N(CCOS(C)(=O)=O)CCOS(C)(=O)=O)c([N+](=O)[O-])cc1[N+](=O)[O-]>>CS(=O)(=O)OCCN(CCOS(C)(=O)=O)c1cc(C(=O)O)c([N+](=O)[O-])cc1[N+](=O)[O-],,C1COCCO1,,[K+].[OH-],,test
US20110070317A1,CC(C)(C)OC(=O)N[C@@H]1CCCNC1.O=C(Nc1c[nH]c2ncc(Br)c(F)c12)c1ccc(F)c(Cl)c1>>CC(C)(C)OC(=O)N[C@@H]1CCCN(c2c(Br)cnc3[nH]cc(NC(=O)c4ccc(F)c(Cl)c4)c23)C1,,CCCCO,,,,test
US20060211603A1,O=C(Cl)C(=O)Cl.O=C(O)c1ccc2c(c1)OC(F)(F)O2>>O=C(Cl)c1ccc2c(c1)OC(F)(F)O2,,CN(C)C=O,,,,test
US20140249104A1,COc1ccc(CCl)cc1.Cc1cc(O)cnc1Cl>>COc1ccc(COc2cnc(Cl)c(C)c2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05444066,CNC(=S)C1(n2cnc([N+](=O)[O-])c2)CCCCC1O.COc1ccc(CCl)cc1>>CN=C(SCc1ccc(OC)cc1)C1(n2cnc([N+](=O)[O-])c2)CCCCC1O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04552882,CC(=O)O.CCn1cc(C(=O)O)c(=O)c2ccc(N)nc21.COC1CCC(OC)O1>>CCn1cc(C(=O)O)c(=O)c2ccc(-n3cccc3)nc21,,CC(=O)O,,,,test
US20120022054A1,COc1ccc(F)cc1CN(C)C(=O)CCCSc1ccc(O)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(F)cc1CN(C)C(=O)CCCS(=O)c1ccc(O)cc1,,ClCCl,,O=C([O-])O.[Na+],,test
US20040225108A1,CC(=O)NCSC[C@H](NC(=O)OC(C)(C)C)C(=O)O.COC(=O)[C@@H](N)Cc1ccccc1>>COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CSCNC(C)=O)NC(=O)OC(C)(C)C,,C1CCOC1,CS(C)=O,CN1CCOCC1,Cl,test
US06380249B1,CCOC(=O)C(=O)CC(=O)c1cccc(N(Cc2ccccc2)Cc2ccccc2)c1>>O=C(O)C(=O)CC(=O)c1cccc(N(Cc2ccccc2)Cc2ccccc2)c1,,C1CCOC1,,[Li+].[OH-],,test
US20100160357A1,CCCCCCCOc1ccc2c(ccc[n+]2[O-])c1.CCOC(=O)C(C)[N+](=O)[O-]>>CCCCCCCOc1ccc2nc(C(C)(C(=O)OCC)[N+](=O)[O-])ccc2c1,,CN(C)C=O,CN(C)C=O,CC(=O)OC(C)=O,,test
US20160159752A1,O=C(O)CC1(c2ccc(Cl)cc2)CCOCC1.O=S(Cl)Cl>>O=C(Cl)CC1(c2ccc(Cl)cc2)CCOCC1,,ClCCl,,,,test
US20110201555A1,Cn1cncc1-c1c(C=O)c2ccccc2n1-c1ccc(O)cc1.NO>>Cn1cncc1-c1c(C=NO)c2ccccc2n1-c1ccc(O)cc1,,CCO,,Cl,c1ccncc1,test
US04906654,NN(Cc1ccc(Cl)cc1)c1ccc(F)cc1.O=C(O)CC1CCCCC(=O)C1>>O=C(O)CC1CCCCc2c1c1cc(F)ccc1n2Cc1ccc(Cl)cc1,,CC(C)(C)O,,Cl,,test
US20080207897A1,O=C(NCC#Cc1c(Cl)ccc2c1CCN(C(=O)C(F)(F)F)CC2)C1CCCC1>>O=C(NC/C=C\c1c(Cl)ccc2c1CCN(C(=O)C(F)(F)F)CC2)C1CCCC1,[Pd],CCOC(C)=O,,,,test
US20130046013A1,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCOC(CC)C(=O)Nc1ccc(O)c(C(=O)OC)c1>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCOC(CC)C(=O)Nc1ccc(O)c(C(=O)O)c1,,CO,,Cl,[Na+].[OH-],test
US20070054916A1,Cc1ccc(C(=O)O)cc1B1OC(C)(C)C(C)(C)O1.Nc1cccc(C(F)(F)F)c1>>Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1B1OC(C)(C)C(C)(C)O1,,ClCCl,,CCN(CC)CC,O=S(Cl)Cl,test
US20090048203A1,Clc1nc(-c2ccccn2)nc2c1ncn2C1CCCO1.N>>Nc1nc(-c2ccccn2)nc2c1ncn2C1CCCO1,,CO,,,,test
US20060252931A1,C1CN(C2CCOCC2)CCN1.Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)O)cc(Cl)c1OCc1ccccc1>>Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCN(C3CCOCC3)CC2)cc(Cl)c1OCc1ccccc1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20030069287A1,CCOC(=O)CN(C(C)=O)S(=O)(=O)c1ccc(-c2c(-c3ccccc3)noc2C)cc1>>Cc1onc(-c2ccccc2)c1-c1ccc(S(=O)(=O)NCC(=O)O)cc1,,CO,O,[Li]O,,test
US20110190490A1,CC(C)(C)OC(=O)CBr.CCCOc1nc(Cc2ccc(Cl)cc2)nc2oc(-c3cc(C)c(O)c(C)c3)nc12>>CCCOc1nc(Cc2ccc(Cl)cc2)nc2oc(-c3cc(C)c(OCC(=O)OC(C)(C)C)c(C)c3)nc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06307056B1,COc1ccccc1B(O)O.O=C1Nc2cccc(I)c2/C1=C/c1ccc[nH]1>>COc1ccccc1-c1cccc2c1/C(=C/c1ccc[nH]1)C(=O)N2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20090291940A1,CCC(=O)c1ccccc1NC(=O)CC(=O)OCc1ccccc1>>CCc1c(C(=O)OCc2ccccc2)c(O)nc2ccccc12,,CCO,,CC(C)(C)[O-].[K+],,test
US20020052376A1,COC(=O)c1ccc(C(OCCc2cncn2C)c2nccs2)cc1-c1ccc(F)cc1>>Cn1cncc1CCOC(c1ccc(C(=O)O)c(-c2ccc(F)cc2)c1)c1nccs1,,CO,O,[Na+].[OH-],,test
US05753595,COC(C)(C)C(=O)Nc1ccc(F)c(Cl)c1.O=C=O>>COC(C)(C)c1nc2ccc(F)c(C(=O)O)c2o1,,C1CCOC1,,[Li]CCCC,,test
US20140336185A1,COC(=O)c1ccc(CC(=O)Nc2ccc(OC)cc2C(F)(F)F)cc1>>COc1ccc(NC(=O)Cc2ccc(C(=O)O)cc2)c(C(F)(F)F)c1,,CCO,,[Na+].[OH-],,test
US20130331378A1,O=C(O)c1c(-c2ccccc2)nn2cc(Br)ccc12>>Brc1ccc2cc(-c3ccccc3)nn2c1,,Clc1ccccc1Cl,,,,test
US20100286170A1,CC(C)(C)OC(=O)N1CCC[C@]1(C)C(=O)[O-]>>CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US04174448,COCCl.NCCc1cccs1>>Cl.c1cc2c(s1)CCNC2,,CN(C)C=O,,,,test
US20100298325A1,COc1cc(N)c(F)cc1F.Clc1ccc(Oc2cccc(N3CCOCC3)c2)cn1>>COc1cc(Nc2ccc(Oc3cccc(N4CCOCC4)c3)cn2)c(F)cc1F,,C1COCCO1,CCOC(C)=O,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US05824691,COC(=O)c1cc(C(=O)O)cc(-n2cccc2)c1.OC1CCNCC1>>COC(=O)c1cc(C(=O)N2CCC(O)CC2)cc(-n2cccc2)c1,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US05495023,C/C=C(/C=C/CO)CC.CCN=C=O>>C/C=C(/C=C/COC(=O)NCC)CC,,ClCCCl,,,,test
US20030065182A1,O=C(O)c1ccc(C(F)(F)F)cc1.O=[N+]([O-])O>>O=[N+]([O-])c1cc(CO)ccc1C(F)(F)F,,O=S(=O)(O)O,,,,test
US05703050,N#Cc1ccc(C(Cc2ccccc2)=NO)cc1>>N#Cc1ccc(CNCc2ccccc2)cc1,,CCO,,Cl,,test
US20090264431A1,CC(C)(C)OC(=O)N1C[C@H](NS(=O)(=O)c2cc(Br)ccc2Br)C[C@@H]1CO.O=C(n1ccnc1)n1ccnc1>>CC(C)(C)OC(=O)N1C[C@H](NS(=O)(=O)c2cc(Br)ccc2Br)C[C@@H]1COC(=O)n1ccnc1,,ClCCl,,,,test
US20140163032A1,CC(C)(C)OC(=O)NC(=NS(=O)(=O)C(F)(F)F)NC(=O)OC(C)(C)C.COc1cccc(C(=O)Nc2ccc(OCCN)c(-c3ccnn3C)c2)c1>>COc1cccc(C(=O)Nc2ccc(OCCNC(=N)N)c(-c3ccnn3C)c2)c1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20160009683A1,CI.O=C(Nc1ccccc1I)OCc1ccccc1>>CN(C(=O)OCc1ccccc1)c1ccccc1I,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130109677A1,Cc1csc2c1C(=O)CC2C[N+](=O)[O-]>>Cc1csc2c1CCC2C[N+](=O)[O-],,C1CCOC1,,,,test
US03962438,ClP(Cl)Cl.O=C(O)c1cccc2c1Nc1cc(C(F)(F)F)ccc1S2>>O=C(Cl)c1cccc2c1Nc1cc(C(F)(F)F)ccc1S2,,CN(C)C=O,,ClC(Cl)Cl,,test
US20160083403A1,Cc1cc(C)cc(C(=O)N(NC(=O)c2ccc(C=O)c(B3OC(C)(C)C(C)(C)O3)c2)C(C)(C)C)c1.NNc1ccccc1>>Cc1cc(C)cc(C(=O)N(NC(=O)c2ccc3c(c2)B(O)N(c2ccccc2)N=C3)C(C)(C)C)c1,,CCO,,ClCCl,,test
US20080076705A1,CC(C)(C)OC(=O)CCCCCCCCCCCCCCBr.COC(=O)c1cc(O)cc(C(=O)OC)c1>>COC(=O)c1cc(OCCCCCCCCCCCCCCC(=O)OC(C)(C)C)cc(C(=O)OC)c1,,CCCCCCC,CCOC(C)=O,CC#N,O=C([O-])[O-].[K+].[K+],test
US20110306587A1,Brc1ccc2ccccc2n1.Clc1nccnc1C1CNC1>>Clc1nccnc1C1CN(c2ccc3ccccc3n2)C1,,CN(C)C=O,O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20150038528A1,COC(=O)C(C)(C)CNC(=O)c1nc(C#N)c2cc(Sc3ccccc3)ccc2c1O>>CC(C)(CNC(=O)c1nc(C#N)c2cc(Sc3ccccc3)ccc2c1O)C(=O)O,,CO,,Cl,[Na+].[OH-],test
US06310096B1,C=C(C)C(=C)C.CON=C(C#CC(=O)c1cccc(Br)c1)C(=O)OC>>CON=C(C(=O)OC)C1=C(C(=O)c2cccc(Br)c2)CC(C)=C(C)C1,,Cc1ccccc1,,,,test
US20120040953A1,COC(=O)[C@@H](C)OC1CN(C(=O)OC(C)(C)C)C1.O=C(O)C(F)(F)F>>COC(=O)[C@@H](C)OC1CNC1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20160237090A1,C[C@H]1Cn2ncc(N3CC4(CC3=O)CN(C(=O)OC(C)(C)C)C4)c2CN1.O=C=Nc1ccc(F)c(Cl)c1>>C[C@H]1Cn2ncc(N3CC4(CC3=O)CN(C(=O)OC(C)(C)C)C4)c2CN1C(=O)Nc1ccc(F)c(Cl)c1,,ClCCl,O,CCN(CC)CC,,test
US20160251339A1,COc1ccc(S(=O)(=O)n2cc(C(F)F)c3ccc(Br)cc32)cc1N1CCN(C(=O)C(Cl)(Cl)Cl)CC1>>COc1ccc(S(=O)(=O)n2cc(C(F)F)c3ccc(Br)cc32)cc1N1CCNCC1,,C1CCOC1,,[K+].[OH-],,test
US20070149508A1,Nc1ccc(F)cc1[N+](=O)[O-].O=C1CCC(=O)N1Br>>Nc1c(Br)cc(F)cc1[N+](=O)[O-],,CN(C)C=O,,O,,test
US04597902,CC(C)N(CCS(=O)(=O)c1ccc(Cl)c(Cl)c1)C(=O)Oc1ccccc1>>CC(C)NCCS(=O)(=O)c1ccc(Cl)c(Cl)c1,,Br,,,,test
US05733914,CSc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1.NCc1ccccc1>>Cn1c(=O)c(-c2c(Cl)cccc2Cl)cc2cnc(NCc3ccccc3)nc21,,CN(C)C=O,,,,test
US20130178460A1,CC(C)(C)OC(=O)N[C@H]1COCC[C@H]1N.Cn1ccc(NC(=O)c2csc3cnc(Cl)nc23)n1>>Cn1ccc(NC(=O)c2csc3cnc(N[C@@H]4CCOC[C@@H]4NC(=O)OC(C)(C)C)nc23)n1,,C1COCCO1,ClCCl,CCN(C(C)C)C(C)C,,test
US20140163000A1,CC(C)(C)OC(=O)N1CCN2[C@@H](CCS2(=O)=O)C1>>O=S1(=O)CC[C@H]2CNCCN21,,ClCCl,,O=C(O)C(F)(F)F,,test
US05410052,CCCNCCCN.O=Cc1ccccn1>>CCCN1CCCNC1c1ccccn1,,c1ccccc1,,,,test
US20130131075A1,CC(=O)c1ccc(Nc2ccccc2C(F)(F)F)cn1.NO>>CC(=NO)c1ccc(Nc2ccccc2C(F)(F)F)cn1,,CCO,,,,test
US20070043065A1,CCO.Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(N2CCN(C)CC2)cc1[N+](=O)[O-]>>Cc1ccc(C(=O)NC2CC2)cc1-n1cnc2cc(N3CCN(C)CC3)ccc2c1=O,[Pd],,,,,test
US20070037812A1,BrCc1ccccc1.Cc1cc(O)cc(O)c1>>Cc1cc(O)cc(OCc2ccccc2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030207877A1,CC(C)[Si](OC(=CCl)c1ncccn1)(C(C)C)C(C)C>>O=C(CCl)c1ncccn1,,CC#N,,O=C([O-])O.[Na+],,test
US20090264428A1,O=C1CCCCC1.Oc1ccccc1O>>c1ccc2c(c1)OC1(CCCCC1)O2,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,,,test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCC1CCN(C)CC1.Oc1ccc2[nH]ccc2c1>>COc1cc2c(Oc3ccc4[nH]ccc4c3)ncnc2cc1OCC1CCN(C)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080221201A1,C1CCNC1.O=S(=O)(Cl)c1ccc(Br)cc1C(F)(F)F>>O=S(=O)(c1ccc(Br)cc1C(F)(F)F)N1CCCC1,,ClCCl,,,,test
US20140140956A1,COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCO[Si](C)(C)C(C)(C)C)c(-c4ccc(S(C)(=O)=O)cc4)n3)nc2c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCO)c(-c4ccc(S(C)(=O)=O)cc4)n3)nc2c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140302993A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccc2c(c1)C1NC(=O)CC1C2>>COC(=O)c1ccc2c(c1)C1C(CC(=O)N1C(=O)OC(C)(C)C)C2,,CC#N,CCOC(C)=O,CCN(CC)CC,CN(C)c1ccccn1,test
US20060019965A1,CC(=O)C=O.Nc1ccncc1N>>Cc1cnc2ccncc2n1,,CO,,CCOC(C)=O,,test
US20090233879A1,CC1(F)[C@H](n2ccc(=O)[nH]c2=O)OC(CO)[C@@]1(C)O.CCCC(=O)Cl>>CCCC(=O)OC[C@H]1OC(n2ccc(=O)[nH]c2=O)[C@](C)(F)C1(C)O,,ClCCl,,O,,test
US20100041663A1,COC(=O)c1cnc(Cl)cn1.Cc1c(-c2ccc(F)cc2)nnc(N2CCN[C@H](C)C2)c1C>>COC(=O)c1cnc(N2CCN(c3nnc(-c4ccc(F)cc4)c(C)c3C)C[C@H]2C)cn1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20150266893A1,COC(=O)c1ccccc1N.COc1cc2c(cc1OC)CCC(C(=O)Cl)=C2>>COC(=O)c1ccccc1NC(=O)C1=Cc2cc(OC)c(OC)cc2CC1,,ClCCl,,CCN(CC)CC,,test
US20100286123A1,CC(C)(C)C1CN(CC2OCCc3c(C#N)cccc32)CCN1C(=O)[O-]>>N#Cc1cccc2c1CCOC2CN1CCNCC1,,ClCCl,,C1COCCO1,Cl,test
US20030060453A1,Cn1nnc2cc([N+](=O)[O-])ccc21>>Cn1nnc2cc(N)ccc21,,Cl,,Cl[Sn]Cl,,test
US20060287536A1,CCC(=O)O.CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc(C)c(S(N)(=O)=O)s1>>CCC(=O)NS(=O)(=O)c1sc(C(CC)(CC)c2ccc(OCC(=O)C(C)(C)C)c(C)c2)cc1C,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US20130178478A1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1N.NC(=O)c1nnc(Cl)cc1Nc1cccc(C2CCC2)n1>>CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1cc(Nc2cccc(C3CCC3)n2)c(C(N)=O)nn1,,CN1CCCC1=O,,,,test
US20140107097A1,Cl.Cn1cncc1C(=O)c1ccc(Cl)cc1.O=c1[nH]c2ccc(Br)cc2c(O)c1-c1ccccc1>>Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2ncc(-c3ccccc3)c(Cl)c2c1,,C1CCOC1,,[Li]CCCC,,test
US06632919B1,COC(=O)CN(CCNC(=O)OC(C)(C)C)C(=O)CCc1ccc(=O)[nH]n1>>CC(C)(C)OC(=O)NCCN(CC(=O)O)C(=O)CCc1ccc(=O)[nH]n1,,C1CCOC1,,O,[Li+].[OH-],test
US04482556,CCOC(=O)OCC.COc1cc2c(cc1OC)C(=CC(N)=O)NCC2>>COc1cc2c(cc1OC)-c1cc(=O)[nH]c(=O)n1CC2,,CCO,,C,C[O-].[Na+],test
US20080167368A1,CCCC(=O)Cl.NC(=O)c1c(-c2ccc([N+](=O)[O-])cc2)c[nH]c1N>>CCCC(=O)Nc1[nH]cc(-c2ccc([N+](=O)[O-])cc2)c1C(N)=O,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20040192708A1,O=C(CC(=O)OCc1ccccc1)OCc1ccccc1.O=[N+]([O-])c1ccc(Cl)nc1>>O=C(OCc1ccccc1)C(C(=O)OCc1ccccc1)c1ccc([N+](=O)[O-])cn1,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US05594023,CCN(CC)C(=O)Nc1ccc(S(=O)(=O)N2C(=O)C(c3ccccc3Cl)(N(C)C)c3cc(Cl)ccc32)cc1.CI>>CCN(CC)C(=O)N(C)c1ccc(S(=O)(=O)N2C(=O)C(c3ccccc3Cl)(N(C)C)c3cc(Cl)ccc32)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20100204240A1,Cc1ccnc(C)c1Oc1cc(Br)cnc1C#N.S=c1cccc[nH]1>>Cc1ccnc(C)c1Oc1cc(Sc2ccccn2)cnc1C#N,,O,,CN(C)C=O,[H-].[Na+],test
US04053608,CC(=O)OC(C)=O.NC(=O)c1cc([N+](=O)[O-])cnc1C(Br)Br>>CC(=O)NC(=O)c1cc([N+](=O)[O-])cnc1C(Br)Br,O=S(=O)(O)O,,,O=C([O-])O.[Na+],,test
US20030073641A1,COC(=O)[O-].O=C1CCc2ccccc21>>COC(=O)C1Cc2ccccc2C1=O,,c1ccccc1,,[H-].[Na+],,test
US20110288292A1,Brc1ccc(CCC2(CCc3ccc(Br)cc3)CO2)cc1>>Brc1ccc2c(c1)C1c3cc(Br)ccc3CCC1CC2,Cl[Ti](Cl)(Cl)Cl,Clc1ccccc1,,,,test
US05521173,O=C(Cl)c1ccc(-c2ccccc2)cc1.c1ccc2c(c1)NCc1cccn1-2>>O=C(c1ccc(-c2ccccc2)cc1)N1Cc2cccn2-c2ccccc21,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,,test
US20160257653A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1cc(Br)cc(C#N)c1>>Cc1cc(Br)cc(CNC(=O)OC(C)(C)C)c1,,CO,,[BH4-].[Na+],,test
US05763700,Brc1cccc(Oc2ccccc2)c1.CC(=O)OCC(F)=CC1(c2ccc(Cl)cc2)CC1>>FC(=CC1(c2ccc(Cl)cc2)CC1)Cc1cccc(Oc2ccccc2)c1,,C1CCOC1,O,II,[Mg],test
US04684654,CCOC(=O)Cl.Nc1ccccc1C(=O)NCCCn1ccnc1>>O=c1[nH]c2ccccc2c(=O)n1CCCn1ccnc1,,CCO,,,,test
US20160096830A1,CC(=O)Cl.O=C(NCCCC[C@H](NC(=O)[C@@H]1CCCNC1)C(=O)c1nc2ccccc2s1)OCc1ccccc1>>CC(=O)N1CCC[C@@H](C(=O)N[C@@H](CCCCNC(=O)OCc2ccccc2)C(=O)c2nc3ccccc3s2)C1,,ClCCl,,Cl,,test
US05679683,CC(=O)Nc1cc2ncnc(Nc3cccc(Br)c3)c2cc1[N+](=O)[O-]>>Nc1cc2ncnc(Nc3cccc(Br)c3)c2cc1[N+](=O)[O-],,CO,O,[K+].[OH-],,test
US20140275027A1,CC(C)(C)OC(=O)N1CC(CO)OCC1(C)C>>CC(C)(C)OC(=O)N1CC(C=O)OCC1(C)C,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US20080214621A1,CI.O=C1C(Cc2cccc3ccccc23)CCN1C1CCCCC1>>CC1(Cc2cccc3ccccc23)CCN(C2CCCCC2)C1=O,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20050227959A1,Cl.Nc1csc2c1CCCC2=O.O=C1CCC(=O)N1Br>>Cl.Nc1c(Br)sc2c1CCCC2=O,,CN(C)C=O,,,,test
US20110039841A1,C#CCBr.CC(=O)N1CCNCC1>>C#CCN1CCN(C(C)=O)CC1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130096113A1,COc1ccc2c(c1)ncn2Cc1ccc2nc(S(C)=O)oc2c1.N[C@@H]1CCCC[C@H]1O>>COc1ccc2c(c1)ncn2Cc1ccc2nc(N[C@@H]3CCCC[C@H]3O)oc2c1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,O,test
US20080234255A1,COC(=O)C(C)CN(c1nc(Cl)ncc1[N+](=O)[O-])C1CCCC1>>COC(=O)C(C)CN(c1nc(Cl)ncc1N)C1CCCC1,[Pd],CCOC(C)=O,,[H][H],,test
US20040058904A1,Cc1ccccc1N=C=O.Nc1ccc(N)cc1>>Cc1ccccc1NC(=O)Nc1ccc(N)cc1,,CCOC(C)=O,,,,test
US20140005132A1,CC(=O)OCC(=O)[C@H]1CCC2C3CC=C4C[C@@H](O[Si](c5ccccc5)(c5ccccc5)C(C)(C)C)CC[C@]4(C)C3CC[C@@]21C>>CC(C)(C)[Si](O[C@H]1CC[C@@]2(C)C(=CCC3C2CC[C@@]2(C)C3CC[C@@H]2C(=O)CO)C1)(c1ccccc1)c1ccccc1,,C1CCOC1,CO,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20100267697A1,Nc1ccc(F)cc1.O=Cc1cnc(N2CCCCC2)nc1>>Fc1ccc(NCc2cnc(N3CCCCC3)nc2)cc1,,CCOC(C)=O,ClCCl,CC(=O)O,[Na+].[OH-],test
US20150126490A1,CC(C)(C)[S@](=O)N[C@H](C[N+](=O)[O-])c1cc(F)cc(Br)c1>>CC(C)(C)[S@](=O)N[C@H](CN)c1cc(F)cc(Br)c1,O=[Pt]=O,CO,,[H][H],,test
US20040229937A1,COC(=O)c1cc(Oc2cccc(NC(=O)Nc3ccc4c(cnn4C)c3)c2)ccn1>>Cn1ncc2cc(NC(=O)Nc3cccc(Oc4ccnc(C(=O)O)c4)c3)ccc21,,CO,O,[K+].[OH-],,test
US04824848,CCCn1c(=O)cc(NN)n(Cc2ccc(F)cc2)c1=O.CN=C=S>>CCCn1c(=O)c2c(NC)n[nH]c2n(Cc2ccc(F)cc2)c1=O,,CN(C)C=O,,CO,,test
US20120258949A1,Cn1cc(CN2CCCC3(CC2)CC(=O)c2cc(/C=C/C(=O)NOC4CCCCO4)ccc2O3)c2ccccc21>>Cn1cc(CN2CCCC3(CC2)CC(=O)c2cc(/C=C/C(=O)NO)ccc2O3)c2ccccc21,,C1COCCO1,ClCCl,Cl,,test
US20050240017A1,COc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(Cc3ccccc3OC)ccc2c1>>O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(Cc2ccccc2O)ccc2cc(O)ccc12,,ClCCl,,BrB(Br)Br,,test
US20090186870A1,COC(=O)c1cc(NN)ccc1Cl.COC(CC(C)=O)OC>>COC(=O)c1cc(-n2nccc2C)ccc1Cl,,CO,,,,test
US20070129345A1,Cc1cc([N+](=O)[O-])cnc1N1CCC2(CC1)CCN([C@@H]1CC[C@H](O)CC1)C2=O>>Cc1cc(N)cnc1N1CCC2(CC1)CCN([C@@H]1CC[C@H](O)CC1)C2=O,[Pd],CO,,,,test
US20160002204A1,Cc1ccc(CNC(=O)c2nnc(CCCCn3ccc(NC(=O)OC(C)(C)C)c(F)c3=O)s2)cn1>>Cc1ccc(CNC(=O)c2nnc(CCCCn3ccc(N)c(F)c3=O)s2)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110077248A1,CC(C)(C)OC(=O)Nc1cccc(CN2CCOCC2)n1>>Nc1cccc(CN2CCOCC2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120077828A1,CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)cn1.Nc1ncc(I)c2scc(-c3ccc4c(c3)CCN4C(=O)Cc3cc(F)ccc3F)c12>>Nc1ncc(-c2cn[nH]c2)c2scc(-c3ccc4c(c3)CCN4C(=O)Cc3cc(F)ccc3F)c12,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20140294724A1,COc1ccc2[nH]cc(CCN)c2c1.O=C(CCCCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O>>COc1ccc2[nH]cc(CCNC(=O)CCCCCN3C(=O)C=CC3=O)c2c1,,ClCCl,,,,test
US05153227,CC(=O)Nc1ccc(S(=O)(=O)C[N+](=O)[O-])cc1>>Nc1ccc(S(=O)(=O)C[N+](=O)[O-])cc1,,CCO,,Cl,O,test
US20140349993A1,CCOC(=O)c1cnc2ccc(Cl)nn12.OB(O)c1ccccc1C(F)(F)F>>CCOC(=O)c1cnc2ccc(-c3ccccc3C(F)(F)F)nn12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120214766A1,CC(C)(C)S(=O)NC1(C(F)(F)F)COC1.Cl>>Cl.NC1(C(F)(F)F)COC1,,CO,,C1COCCO1,,test
US20090042929A1,NCCc1cccs1.O=C(Cl)CC12CC3CC(CC(C3)C1)C2>>O=C(CC12CC3CC(CC(C3)C1)C2)NCCc1cccs1,,ClCCl,,CCN(CC)CC,,test
US20020161041A1,COCOc1ccc(C2CCCC(NC(C)=O)C2)c(OCOC)c1>>CC(=O)NC1CCCC(c2ccc(O)cc2O)C1,,CO,,,,test
US20080182842A1,CCOC(=O)C(C)(C)C(=O)N1CCCC1>>CC(C)(C(=O)O)C(=O)N1CCCC1,,CCO,,[K+].[OH-],,test
US20150336949A1,Cc1ccc(S(=O)(=O)n2cc(-c3cnn(Cc4cccc(C)c4)c3)c3cc(-c4ccc(N5CCN(C(=O)OC(C)(C)C)CC5)nc4)cnc32)cc1.Cl>>Cc1ccc(S(=O)(=O)n2cc(-c3cnn(Cc4cccc(C)c4)c3)c3cc(-c4ccc(N5CCNCC5)nc4)cnc32)cc1.Cl,,CCOCC,CO,,,test
US20120225062A1,CCOS(=O)(=O)OCC.C[C@@H]1C[C@H](NC(=O)OC(C)(C)C)C[C@H](c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cc(C=O)cc3F)n2)C1>>CCOc1cc(F)c(-c2nc(C(=O)Nc3cnccc3[C@H]3C[C@@H](NC(=O)OC(C)(C)C)C[C@@H](C)C3)ccc2F)c(F)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04477466,CC(=O)Cl.NS(=O)(=O)c1ccc(S(=O)(=O)c2ccc(O)cc2)s1>>CC(=O)Oc1ccc(S(=O)(=O)c2ccc(S(N)(=O)=O)s2)cc1,,CC(C)=O,,CCN(CC)CC,,test
US20130059834A1,Cc1ccc2c(-c3cnc4c(n3)c(C(=O)NC(C)(C)CO[Si](C)(C)C(C)(C)C)cn4C(c3ccccc3)(c3ccccc3)c3ccccc3)n[nH]c2c1.ClCCCN1CCOCC1>>Cc1ccc2c(-c3cnc4c(n3)c(C(=O)NC(C)(C)CO[Si](C)(C)C(C)(C)C)cn4C(c3ccccc3)(c3ccccc3)c3ccccc3)nn(CCCN3CCOCC3)c2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05494928,C[C@H]1CO1.Fc1ccc2[nH]ccc2c1>>C[C@H](O)Cn1ccc2cc(F)ccc21,,C1CCOC1,CCOCC,O,[H-].[Na+],test
US20090181942A1,COc1ccc(Cn2nnc(CCO)n2)cc1.COc1cccc([C@H]2O[C@H](CCn3ccc(COS(C)(=O)=O)n3)c3cccn3-c3ccc(Cl)cc32)c1OC>>COc1ccc(Cn2nnc(CCOS(C)(=O)=O)n2)cc1,,CCN(CC)CC,,CS(=O)(=O)Cl,,test
US20150376189A1,Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1.NC(=O)C(O)c1cccnc1>>O=C(Nc1ccc2ncc(-c3cc4ccccc4o3)n2n1)C(O)c1cccnc1,,CCCCCC,CN(C)C=O,[H-].[Na+],,test
US20140256723A1,CS(=O)(=O)Cl.Nc1ccc(N)c([N+](=O)[O-])c1>>CS(=O)(=O)Nc1ccc(N)c([N+](=O)[O-])c1,,c1ccncc1,,,,test
US20090221555A1,BrCCOCCBr.CCN1C(=O)C(N)CCc2c1ccc([N+](=O)[O-])c2OC>>CCN1C(=O)C(N2CCOCC2)CCc2c1ccc([N+](=O)[O-])c2OC,,CC#N,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20020022722A1,CC[Si](C#C[C@]1(COCc2ccccc2)O[C@@H](n2cnc3c(N)ncnc32)[C@H](OC(C)=O)[C@@H]1OCc1ccccc1)(CC)CC>>CC[Si](C#C[C@]1(COCc2ccccc2)O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OCc1ccccc1)(CC)CC,,CCN(CC)CC,CO,,,test
US20140171390A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)CC1CC(NCc2ccc(OC)cc2OC)C1>>COC(=O)CC1CC(N(Cc2ccc(OC)cc2OC)C(=O)OC(C)(C)C)C1,,ClCCl,,,,test
US20020099089A1,COC(=O)c1cc(-n2nc(C)cc2C)ccc1[N+](=O)[O-]>>COC(=O)c1cc(-n2nc(C)cc2C)ccc1N,,CO,,,,test
US04363813,COc1cc(-c2nc(C)c(C(C)=O)s2)cc(OC)c1OC.NO>>COc1cc(-c2nc(C)c(C(C)=NO)s2)cc(OC)c1OC,,CCO,,O,[Na+].[OH-],test
US05846982,BrCC1CC1.Oc1cccc2[nH]ccc12>>c1cc(OCC2CC2)c2cc[nH]c2c1,,CN(C)C=O,,[H-].[Na+],,test
US20160263122A1,O=C(Nc1nnc(-c2ccccc2)s1)c1ccc(OCc2ccccc2)c(NC(=O)C2(N3CCOCC3)CC2)c1>>O=C(Nc1nnc(-c2ccccc2)s1)c1ccc(O)c(NC(=O)C2(N3CCOCC3)CC2)c1,[Pd],CCO,,C1CCOC1,,test
US06413938B1,CC(=O)[C@@]1(O)[C@@H](C)O[C@@H](n2cnc3cc(Cl)c(Cl)cc32)[C@@H]1F.O=C1CCC(=O)N1Br>>CC(=O)[C@@]1(O)[C@@H](C)O[C@@H](n2c(Br)nc3cc(Cl)c(Cl)cc32)[C@@H]1F,,Cc1ccccc1,,,,test
US20090197877A1,CCCC[Sn](CCCC)(CCCC)c1cccc(OC)n1.CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(Br)c2s1>>CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(-c3cccc(OC)n3)c2s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US20090035215A1,BrCCCOC1CCCCO1.Cc1cc(O)cc(C)c1Br>>Cc1cc(OCCCOC2CCCCO2)cc(C)c1Br,,CS(C)=O,ClCCl,O,[K+].[OH-],test
US20130059883A1,CCOC(=O)CCc1nc(-c2ccc(F)cc2)cs1>>O=C(O)CCc1nc(-c2ccc(F)cc2)cs1,,CO,,[Na+].[OH-],,test
US20130225554A1,Cn1ncc2c1CN(C(=O)OC(C)(C)C)CC2ONC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1>>Cn1ncc2c1CN(C(=O)OC(C)(C)C)CC2ONC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2O,[Pd],CO,,,,test
US04593102,ON=C1CCC(Sc2ccccc2)CC1>>c1ccc(SC2CCCNCC2)cc1,,ClCCl,,CC(C)C[Al+]CC(C)C.[H-],,test
US20100125066A1,CC(=O)OCC(=O)N1Cc2cc(Cl)ccc2-n2c(nnc2[C@@H]2CC[C@@H](OC(C)C)CC2)C1>>CC(C)O[C@@H]1CC[C@@H](c2nnc3n2-c2ccc(Cl)cc2CN(C(=O)CO)C3)CC1,,CO,,C[O-].[Na+],,test
US04198424,COc1cccc(C(=O)CC2CCCN2)c1>>COc1cccc(C(O)CC2CCCN2)c1,,CO,O,Cl,[BH4-].[Na+],test
US20160184305A1,COc1cc(N)c(C(=O)O)cc1Br.N=CN>>COc1cc2[nH]cnc(=O)c2cc1Br,,CCO,,CC(=O)O,,test
US20080096877A1,CC(C)(C)OC(=O)O.CCOC(=O)c1cc2cc(OCCOC)cc([N+](=O)[O-])c2[nH]1>>CCOC(=O)c1cc2cc(OCCOC)cc([N+](=O)[O-])c2n1C(=O)OC(C)(C)C,CN(C)c1ccncc1,CCOC(C)=O,O,C1CCOC1,,test
US20050164402A1,C=CCCCCCCCCCO.Fc1c(F)c(F)c(CBr)c(F)c1F>>C=CCCCCCCCCCOCc1c(F)c(F)c(F)c(F)c1F,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20080261921A1,CCOC(=O)C(=O)c1cccc(Br)c1.C[Mg]Br>>CCOC(=O)C(C)(O)c1cccc(Br)c1,,CCOCC,,O,,test
US20110081365A1,CO.O=C(O)CCc1ccc(I)cc1>>COC(=O)CCc1ccc(I)cc1,,Cc1ccccc1,,C[Si](C)(C)C=[N+]=[N-],,test
US20050038043A1,CCCc1c(N)nc(C)nc1Cn1ccnc1-c1cccc(F)n1.O=CCCl>>CCCc1c(Cn2ccnc2-c2cccc(F)n2)nc(C)n2ccnc12,,CN(C)C=O,,,,test
US20040058970A1,Clc1onc(-c2ccccc2)c1-c1nnc2n1Cc1ccc(Br)cc1-2.NCc1ccccn1>>NCc1ncccc1-c1onc(-c2ccccc2)c1-c1nnc2n1Cc1ccc(Br)cc1-2,,CO,,CC(=O)[O-].[Na+],,test
US20150011773A1,C#CC[C@@H](C[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.[N-]=[N+]=NCCO>>CC(C)(C)OC(=O)N[C@@H](C[C@H](Cc1cn(CCO)nn1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,[Cu]I,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090264428A1,CCc1cccc(-c2c(Cl)cccc2[C@](O)(CCCNC(=O)CO)[C@@H]2CCCN(C(=O)OC(C)(C)C)C2)c1>>CCc1cccc(-c2c(Cl)cccc2[C@](O)(CCCNC(=O)CO)[C@@H]2CCCNC2)c1,,CC#N,,Cl,,test
US05135914,CC(C)OC(=O)C(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C>>CC(C)OC(=O)C(O)C(CC1CCCCC1)NC(=O)OC(C)(C)C,[Rh],CC(C)O,,,,test
US20090275627A1,CC(C)C(C=O)NC(=O)OC(C)(C)C.COP(=O)(OC)C(=[N+]=[N-])C(C)=O>>C#CC(NC(=O)OC(C)(C)C)C(C)C,,CO,,O=C([O-])[O-].[K+].[K+],,test
US05741796,N[C@H]1CCCC[C@H]1N.S=C=S>>S=C1N[C@@H]2CCCC[C@@H]2N1,,ClCCl,,,,test
US20030125346A1,CC(C)(C)c1cc(Nc2ccnc(Cl)n2)no1.COc1cc(C)c(N)cc1OC>>COc1cc(C)c(Nc2nccc(Nc3cc(C(C)(C)C)on3)n2)cc1OC,,CS(C)=O,ClCCl,O,O=C([O-])O.[Na+],test
US20100172867A1,CNC1Cc2ccccc2N(Cc2ccc(Cl)c(Cl)c2)C1.Nc1nc(Cl)c2cn[nH]c2n1>>CN(c1nc(N)nc2[nH]ncc12)C1Cc2ccccc2N(Cc2ccc(Cl)c(Cl)c2)C1,,CC(=O)N(C)C,O,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20100022572A1,CC(C)(C)OC(=O)N1CCC2(CC1)CC(C)(O)c1ccccc12>>CC1=CC2(CCNCC2)c2ccccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070111995A1,CCOC(=O)c1cnc2c(cnn2CC)c1N[C@H]1CCNC1.C[Si](C)(C)N=C=O>>CCOC(=O)c1cnc2c(cnn2CC)c1N[C@H]1CCN(C(N)=O)C1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20110015242A1,N#Cc1ccc(NN)cc1.O=C(C=C(O)c1ccc2c(ccc3ccccc32)c1)C(F)(F)F>>N#Cc1ccc(-n2nc(C(F)(F)F)cc2-c2ccc3c(ccc4ccccc43)c2)cc1,,CCO,,Cl,,test
US20080207654A1,CCCc1nc(C)n(-c2ccc(SC)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCc1nc(C)n(-c2ccc(SC)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US20150266867A1,C#CCNC(=O)OC(C)(C)C.C[Si](C)(C)N=[N+]=[N-]>>CC(C)(C)OC(=O)NCc1cn[nH]n1,[Cu]I,CN(C)C=O,CO,,,test
US20100292242A1,CC(N)c1cccc(Br)c1.O=C(CBr)c1ccc(Cl)cc1>>CC(NCC(=O)c1ccc(Cl)cc1)c1cccc(Br)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20030207875A1,CC(C)(C)OC(=O)N1CCC(CN)CC1.COc1nc(N)c(Cl)cc1C(=O)O>>CCN1CCC(CNC(=O)c2cc(Cl)c(N)[nH]c2=O)CC1,,CN(C)C=O,,O,O=C(n1ccnc1)n1ccnc1,test
US20110112081A1,BrCc1ccc(Br)cc1.c1c[nH]nn1>>Brc1ccc(Cn2nccn2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140364413A1,C1COCCN1.CCOC(=O)c1cn2nc(Cl)cc(Br)c2n1>>CCOC(=O)c1cn2nc(Cl)cc(N3CCOCC3)c2n1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20080113966A1,Cc1cc(C2CCNCC2)c(=O)[nH]n1.N[C@@H]1CC[C@@H](c2c(F)cccc2F)Cn2c(CC(F)(F)F)cnc21.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>Cc1cc(C2CCN(C(=O)N[C@@H]3CC[C@@H](c4c(F)cccc4F)Cn4c(CC(F)(F)F)cnc43)CC2)c(=O)[nH]n1,,C1CCOC1,ClC(Cl)Cl,CCN(CC)CC,O=C([O-])[O-].[Na+].[Na+],test
US20100063054A1,COc1ccc(CN)c(OC)c1.FC(F)(c1ccc(Cl)nn1)c1nnc2ccc(Br)cn12>>COc1ccc(CNc2ccc(C(F)(F)c3nnc4ccc(Br)cn34)nn2)c(OC)c1,,CC(C)O,,O=C([O-])O.[Na+],,test
US20040039061A1,COC1=C(OC)C(=O)C(Cc2ccc(-c3ccccc3)c(C(=O)O)c2)=C(C)C1=O.COc1ccc(N)cc1>>COC1=C(OC)C(=O)C(Cc2ccc(-c3ccccc3)c(C(=O)Nc3ccc(OC)cc3)c2)=C(C)C1=O,,ClCCl,O,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US20160002188A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.OCc1nc2cc(Br)ccc2[nH]1>>CC(C)(C)OC(=O)OCc1nc2cc(Br)ccc2n1C(=O)OC(C)(C)C,CN(C)c1ccncc1,ClCCl,,,,test
US20120277305A1,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)NCCNC(=O)CN(C)C(=O)OC(C)(C)C>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)NCCNC(=O)CNC,,CCOC(C)=O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20160272632A1,CNC.Clc1ccc2cc(Br)ccc2n1>>CN(C)c1ccc2cc(Br)ccc2n1,,CCOC(C)=O,,,,test
US20030100554A1,CC(=O)C(Cl)C(C)=O.Oc1cc(Cl)cc(Cl)c1>>CC(=O)C(Oc1cc(Cl)cc(Cl)c1)C(C)=O,,CC(C)=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US05008267,Cn1c(NCCOS(C)(=O)=O)c([N+](=O)[O-])c(=O)n(C)c1=O>>Cn1c(N2CC2)c([N+](=O)[O-])c(=O)n(C)c1=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20160068531A1,CCOC(=O)CCn1c(CO[Si](C)(C)C(C)(C)C)cc2cc(Cl)ccc21>>CCOC(=O)CCn1c(CO)cc2cc(Cl)ccc21,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110294776A1,Nc1ncnn2c(CCCNCC3CN(C(=O)O)C3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12>>Nc1ncnn2c(CCCNCC3CNC3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120277325A1,CC(=O)C1C(C)C=CCC1(C)C.CCCCO.N=CN>>CC1C=CCC(C)(C)C1c1ccncn1,,CCCCO,,CC(=O)O,,test
US20140249104A1,O=P(Cl)(Cl)Cl.Oc1ncnc2sc(C(F)F)nc12>>FC(F)c1nc2c(Cl)ncnc2s1,,Cc1ccccc1,,CN(C)c1ccccc1,,test
US20040122029A1,COC(=O)C(Cc1cnc(Cl)nc1Nc1ccccc1)c1ccc(OC)cc1.COc1ccc(N)cn1>>COC(=O)C(Cc1cnc(Nc2ccc(OC)nc2)nc1Nc1ccccc1)c1ccc(OC)cc1,,CCOC(C)=O,,,,test
US20100298287A1,COc1ccc(N2CCCn3c2nc2c(Cl)ccc(C(OC(F)F)C(F)(F)F)c23)c(C)n1>>Cc1nc(O)ccc1N1CCCn2c1nc1c(Cl)ccc(C(OC(F)F)C(F)(F)F)c12,,CC#N,,C[Si](C)(C)Cl,[I-].[Na+],test
US05879894,C/C=C/C(=O)OCc1ccccc1.O=C1CCC(=O)N1Br>>O=C(C=CCBr)OCc1ccccc1,,ClC(Cl)(Cl)Cl,,,,test
US05041436,NCCCCC(=O)O.O=S(=O)(Cl)c1ccc(N2CCCCC2)cc1>>O=C(O)CCCCNS(=O)(=O)c1ccc(N2CCCCC2)cc1,,O,,C1CCOC1,[Na+].[OH-],test
US08716484B1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=S(=O)(Oc1ccc(N(c2ccc(-c3ccccc3)cc2)c2c(-c3ccccc3)cccc2-c2ccccc2)cc1)C(F)(F)F>>CC1(C)OB(c2ccc(N(c3ccc(-c4ccccc4)cc3)c3c(-c4ccccc4)cccc3-c3ccccc3)cc2)OC1(C)C,,C1COCCO1,,ClCCl,CC(=O)[O-].[K+],test
US20130303533A1,CC(C)n1ccc2c(Cl)nc(S(=O)(=O)c3ccc(F)cc3)nc21.Cc1cc(N)n[nH]1>>Cc1cc(Nc2nc(S(=O)(=O)c3ccc(F)cc3)nc3c2ccn3C(C)C)n[nH]1,,CN(C)C=O,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20090215725A1,CC#CCBr.OCC1CCC2(CC1)OCCO2>>CC#CCOCC1CCC2(CC1)OCCO2,,C1CCOC1,,[H-].[Na+],,test
US20080064681A1,C[C@H]1CN(C(=O)OC(C)(C)C)CCCCN1S(=O)(=O)c1cccc2cncc(Br)c12.Cl.ClC(Cl)Cl>>C[C@H]1CNCCCCN1S(=O)(=O)c1cccc2cncc(Br)c12.Cl.Cl,,ClC(Cl)Cl,,C1COCCO1,,test
US20140349991A1,CCC(=O)c1ccc(OCOC)c(C)c1O.S=C=S>>COCOc1ccc2c(O)c(C)c(=S)oc2c1C,,C1CCOC1,O,Cl,CC(C)(C)[O-].[K+],test
US20130059883A1,CCOC(=O)C(=O)NCC(=O)c1ccccc1.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CCOC(=O)c1ncc(-c2ccccc2)s1,,ClC(Cl)Cl,,,,test
US20120010188A1,Nc1ccc(C(F)(F)F)cn1.O=C(CBr)c1ccc(Cl)cc1>>FC(F)(F)c1ccc2nc(-c3ccc(Cl)cc3)cn2c1,,CCO,,[Na+].[OH-],,test
US20080293716A1,NCc1ccccc1.O=C(Cl)c1ccc(Br)s1.OB(O)c1ccncc1>>O=C(NCc1ccccc1)c1ccc(-c2ccncc2)s1,[Pd],,,,,test
US20060106048A1,CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(/C=C/C(=O)OC)c(NC(=O)c3cc4ccccc4[nH]3)c1)=NC(C)(C)C2>>CCOc1cc2c(c3c1OC(C)(C)C3)C(c1ccc(/C=C/C(=O)O)c(NC(=O)c3cc4ccccc4[nH]3)c1)=NC(C)(C)C2,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20130210831A1,C1COCCN1.CN(c1cnc(Br)cn1)[C@@H]1CCN(c2ncnc3c2ccn3COCC[Si](C)(C)C)C1>>CN(c1cnc(N2CCOCC2)cn1)[C@@H]1CCN(c2ncnc3c2ccn3COCC[Si](C)(C)C)C1,,CN1CCCC1=O,,O,,test
US04086238,CCCCCN.COCC(Cl)C=O>>CCCCCNC(C=O)COC,,Cc1ccccc1,,,,test
US20080188442A1,C=O.CCOC(=O)CC(=O)C(F)F.CNN>>CCOC(=O)C1CN(C)N=C1C(F)F,,CCO,,Cl,,test
US20070123492A1,CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](OCCOC1CCCCO1)C(Cc1ccccc1)OOC>>CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](CO)OCCOC1CCCCO1,,ClCCl,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20100056600A1,CC(C)(C)OC(=O)NC1C2CC3CC1CC(O)(C3)C2>>CNC1C2CC3CC1CC(O)(C3)C2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100273786A1,CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2c(C(F)(F)F)nc(C(=O)N3CCSC3)c2C1)Cc1cc(F)c(F)cc1F.Cl>>Cl.N[C@@H](CC(=O)N1CCn2c(C(F)(F)F)nc(C(=O)N3CCSC3)c2C1)Cc1cc(F)c(F)cc1F,,CCOC(C)=O,,,,test
US04343942,CC=O.[O-][n+]1onc2ccccc21>>O=[n+]1ccn([O-])c2ccccc21,,CCN(CC)CC,,,,test
US20030134867A1,CN(C)C1CN(C(=O)Cc2ccc(F)cc2)N(C(=O)OCc2ccccc2)C1>>CN(C)C1CNN(C(=O)Cc2ccc(F)cc2)C1,[Pd],CO,,Cl,,test
US20080131367A1,CC(=O)c1cc(Br)ccc1O.COc1ccc(C(=O)Cl)cc1>>COc1ccc(C(=O)Oc2ccc(Br)cc2C(C)=O)cc1,,c1ccncc1,,Cl,,test
US20020032168A1,CC(=O)OC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CNC(=O)NCCN4CCCCC4)nc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O.N>>N.O=C(NCCN1CCCCC1)NCc1nc(NCC(c2ccccc2)c2ccccc2)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1,,CO,,,,test
US20110312905A1,O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1.O=c1cccccc1O>>O=c1cccccc1OS(=O)(=O)c1ccc([N+](=O)[O-])cc1,,c1ccncc1,,O,,test
US20100286118A1,CC(C)(C)OC(=O)NC1(C(=O)N[C@@H](Cc2ccc(I)cc2)C(N)=O)CCOCC1.CS(=O)(=O)Oc1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)NC1(C(=O)N[C@@H](Cc2ccc(-c3ccc(OS(C)(=O)=O)cc3)cc2)C(N)=O)CCOCC1,,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20090181928A1,CC(=O)Cl.C[Si](C)(C)CCN1C(=O)CN(c2ccc(C[C@@H]3CCCC[C@H]3N)cc2OCc2ccccc2)S1(=O)=O>>CC(=O)N[C@@H]1CCCC[C@H]1Cc1ccc(N2CC(=O)N(CC[Si](C)(C)C)S2(=O)=O)c(OCc2ccccc2)c1,,ClCCl,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20130195848A1,CSc1nc(-c2ccccc2)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1nc(-c2ccccc2)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12,,ClCCl,,,,test
US20160158207A1,CNC(=O)N1CCc2c(c(N3CCCc4cc(-c5ccnc(Cl)n5)c(C#N)cc43)nn2C2CCOCC2)C1>>CNC(=O)N1CCc2c(c(N3CCCc4cc(-c5ccncn5)c(C#N)cc43)nn2C2CCOCC2)C1,[Pd],CO,,,,test
US20090137530A1,CC(C)(C)OC(=O)NC(CO)(CO)CCc1ccc(O)c(C(F)(F)F)c1.CCCCCCCCBr>>CCCCCCCCOc1ccc(CCC(CO)(CO)NC(=O)OC(C)(C)C)cc1C(F)(F)F,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20020107255A1,C[C@H]1CN(C(=O)COc2ccc(Cl)cc2C=O)[C@H](C)CN1Cc1ccc(F)cc1.[NH4+]>>C[C@H]1CN(C(=O)COc2ccc(Cl)cc2CN)[C@H](C)CN1Cc1ccc(F)cc1,,CO,,[BH3-]C#N.[Na+],,test
US06878736B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CS(=O)(=O)NCc1ccc(Cl)cc1>>CC(C)(C)OC(=O)N(Cc1ccc(Cl)cc1)S(C)(=O)=O,,ClCCl,,,,test
US04760158,ClCBr.N#CC1CCCC1>>N#CC1(CCl)CCCC1,,C1CCOC1,CCCCCC,O,CC(C)[N-]C(C)C.[Li+],test
US20160000929A1,C#CCC(CC#C)C(=O)O.CCCCB1O[C@@H]2C[C@H](O1)[C@H](C/C=C\CCCC(=O)OC(C)C)[C@H]2CC[C@@H](O)CCc1ccccc1>>C#CCC(CC#C)C(=O)O[C@@H](CCc1ccccc1)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)OC(C)C,CN(C)c1ccncc1,CO,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05705499,Brc1cccnc1.C#Cc1cnc2c(c1)C(=O)N(C)c1cccnc1N2CC>>CCN1c2ncc(C#Cc3cccnc3)cc2C(=O)N(C)c2cccnc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCN(CC)CC,,,,test
US20120289549A1,BrC(Br)(Br)Br.O=C1N(c2ccc(OC(F)(F)F)cc2)C[C@@H]2C[C@H](O)CN12>>O=C1N(c2ccc(OC(F)(F)F)cc2)C[C@@H]2C[C@@H](Br)CN12,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US06399600B1,BrBr.C=C1CC(=O)O1.OCc1ccccc1>>O=C(CBr)CC(=O)OCc1ccccc1,,ClCCl,,,,test
US05117830,CC(=O)OCCOCBr.Clc1ncnc2nc[nH]c12>>CC(=O)OCCOCn1cnc2c(Cl)ncnc21,,CN(C)C=O,,O,[H-].[Na+],test
US20080306109A1,CCOC(=O)Cc1c(C)c(Sc2ccc(S(C)(=O)=O)cc2)c2ccc(C#N)cn12>>Cc1c(Sc2ccc(S(C)(=O)=O)cc2)c2ccc(C#N)cn2c1CC(=O)O,,C1CCOC1,,[Li+].[OH-],,test
US20130317023A1,Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F.O=S(=O)(Cl)c1ccc(C2OCCO2)o1>>O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F)c1ccc(C2OCCO2)o1,,ClCCl,,c1ccncc1,,test
US20090275537A1,CC(C)(C)OC(=O)N1CCNCC1.CN(C(=O)NCc1cccc(F)c1Cl)[C@@H](CCC(=O)O)COC(=O)Nc1nc2ccccc2s1>>CN(C(=O)NCc1cccc(F)c1Cl)[C@@H](CCC(=O)N1CCN(C(=O)OC(C)(C)C)CC1)COC(=O)Nc1nc2ccccc2s1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120184574A1,BrBr.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn3)n(C3CCCC3)c2c1>>Cc1cc2c(cc1Br)c(C#N)c(-c1ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn1)n2C1CCCC1,,O,,,,test
US06329405B1,COc1ccc(C(NCC(c2ccccc2)c2ccccc2)c2cccc(Nc3c(OC)c(=O)c3=O)c2)cc1.N>>COc1ccc(C(NCC(c2ccccc2)c2ccccc2)c2cccc(Nc3c(N)c(=O)c3=O)c2)cc1,,CCO,,,,test
US20110118278A1,CC(C)(NC(=O)c1cc2c(NC(=O)c3ccc(CN4CCCCC4)cc3)n[nH]c2s1)c1ccccc1.CCOC(=O)Cl>>CCOC(=O)n1nc(NC(=O)c2ccc(CN3CCCCC3)cc2)c2cc(C(=O)NC(C)(C)c3ccccc3)sc21,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20110070190A1,CC1(C)OB(c2ccc(N)c(Cl)c2)OC1(C)C.O=c1ncn(Cc2ccc(Cl)cc2)c2cc(Br)sc12>>Nc1ccc(-c2cc3c(s2)c(=O)ncn3Cc2ccc(Cl)cc2)cc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20140094474A1,C[C@H](N)Cn1ccc(-c2cc(F)c(C#N)c(Cl)c2)n1.O=C(O)c1cc(-c2ccn[nH]2)n[nH]1>>C[C@@H](Cn1ccc(-c2cc(F)c(C#N)c(Cl)c2)n1)NC(=O)c1cc(-c2ccn[nH]2)n[nH]1,,O,,CN(C)C=O,,test
US20080176872A1,CCOC(=O)c1nc(N[C@@H](C)c2ccc(F)cc2)nc(Nc2cc(C3CC3)[nH]n2)c1[N+](=O)[O-]>>CCOC(=O)c1nc(N[C@@H](C)c2ccc(F)cc2)nc(Nc2cc(C3CC3)[nH]n2)c1N,[Zn],C1CCOC1,CCO,[Cl-].[NH4+],,test
US20070010526A1,COc1ccc(N2CCN(C)CC2)c2c1CCNC2.Nc1ccc(N2CCSCC2)cc1.O=C(n1ccnc1)n1ccnc1>>COc1ccc(N2CCN(C)CC2)c2c1CCN(C(=O)Nc1ccc(N3CCSCC3)cc1)C2,,ClCCl,,CCN(CC)CC,,test
US04625032,CI.COC(=O)[C@@H]1Cc2c([nH]c3c(C)cccc23)CN1.S=C=S>>CSC(=S)N1Cc2[nH]c3c(C)cccc3c2C[C@H]1C(=O)O,,CO,,[Na+].[OH-],,test
US20160002273A1,Cc1c(C(=O)[O-])ccc(N2CCC(C3OCC(C)(C)CO3)CC2)c1C.NC(=O)c1cc2ncnc(Cl)c2s1>>CC1(C)COC(C2CCN(c3ncnc4cc(C(N)=O)sc34)CC2)OC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20020040048A1,COC(=O)[C@@H]1C[C@H](OS(C)(=O)=O)CN1S(=O)(=O)c1ccc2ccccc2c1.SC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)[C@@H]1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1S(=O)(=O)c1ccc2ccccc2c1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20070135429A1,COc1cc2[nH]cc(C#N)c(=O)c2cc1OC.O=P(Cl)(Cl)Cl>>COc1cc2ncc(C#N)c(Cl)c2cc1OC,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20100056530A1,O=C(NC(=S)Nc1ncc(Br)nc1OCc1ccccc1)c1ccccc1>>NC(=S)Nc1ncc(Br)nc1OCc1ccccc1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20060223814A1,CC(C)(C)OC(=O)N1CCC(CCI)CC1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CC(C)(C)OC(=O)N1CCC(CC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)CC1.[I-],,CC#N,,,,test
US20090253687A1,NC1=NC=C(c2ccc3c(c2)NC(=O)CO3)C(c2ccccc2)S1.O=CCCl>>O=C1COc2ccc(C3=Cn4ccnc4SC3c3ccccc3)cc2N1,,CCO,COCCOC,CCOC(C)=O,O=C([O-])O.[Na+],test
US20130029995A1,CC1CCN(c2nc(C(F)(F)F)ccc2CN)CC1.O=C(Nc1cnc2c(c1)CCC2)Oc1ccccc1>>CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cnc3c(c2)CCC3)CC1,CN(C)c1ccncc1,CN(C)C=O,,,,test
US05661159,CC1(C)CC(=O)OC1=O.Nc1ccc2oc(-c3ccc4ccc(Cl)cc4n3)cc2c1>>CC(C)(CC(=O)Nc1ccc2oc(-c3ccc4ccc(Cl)cc4n3)cc2c1)C(=O)O,,CN(C)C=O,ClCCl,c1ccncc1,,test
US20050288273A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCCC3=O)C(=O)O1.O=C(Cl)C1CCCC1>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCC(C(=O)C2CCCC2)C3=O)C(=O)O1,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20100113782A1,Cc1cc(N)ccc1I.O=C(Cl)c1ccc(Cl)nc1>>Cc1cc(NC(=O)c2ccc(Cl)nc2)ccc1I,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US20030134854A1,CC(=O)Cl.CNCc1cc(C(=O)Nc2nc3c(OC)ccc(N4CCOCC4)c3s2)ccn1>>COc1ccc(N2CCOCC2)c2sc(NC(=O)c3ccnc(CN(C)C(C)=O)c3)nc12,,ClCCl,,c1ccncc1,O=C([O-])O.[Na+],test
US20120165304A1,CN1CCc2nc3ccnn3c(Cl)c2CC1.O=C(O)C1CNC1>>CN1CCc2nc3ccnn3c(N3CC(C(=O)O)C3)c2CC1,,CCO,,CCN(C(C)C)C(C)C,,test
US20070259888A1,CC(C)(C)OC(=O)NCc1ccc(C(=O)O)cc1.CCN(C(C)C)C(C)C.CCO[C@@H]1CCCN(C[C@@H]2CCCC[C@H]2N)C1>>CCOC[C@@H]1CCCN(C[C@H]2CCCC[C@@H]2NC(=O)c2ccc(CNC(=O)OC(C)(C)C)cc2)C1,,CN(C)C=O,,Cl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060167246A1,CI.Cc1ccc(C(=O)O)s1>>COC(=O)c1ccc(C)s1,,CN(C)C=O,,CCOCC,O=C([O-])[O-].[K+].[K+],test
US20050261284A1,COc1ccc(Cl)c(C(=O)Cl)c1.CSc1ncc(Br)c(N(C)N)n1>>COc1ccc(Cl)c(C(=O)NN(C)c2nc(SC)ncc2Br)c1,,ClCCl,,CCN(CC)CC,,test
US20110046378A1,CN(C)c1ccc2c(c1)c1cc(OCc3ccccc3)ccc1n2CO.CO>>COCn1c2ccc(O)cc2c2cc(N(C)C)ccc21,[Pd],CO,,CC(=O)O,,test
US20120208804A1,C#CC(C)(C)N.C=C(C)CC(O)(CCCl)c1ccccc1>>C#CC(C)(C)NCCC(O)(CC(=C)C)c1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04287207,CNC(=O)NC.O=C=Nc1ccccc1>>CNC(=O)N(C)C(=O)Nc1ccccc1,,C1COCCO1,,,,test
US06214873B1,O=C(CCCCc1ccccc1)c1ccc(CCBr)cc1.[I-]>>O=C(CCCCc1ccccc1)c1ccc(CCI)cc1,,CCC(C)=O,,O,,test
US05602170,O.O=Cc1ccc(-c2ccc(-c3cccs3)s2)s1>>O=C(O)c1ccc(-c2ccc(-c3cccs3)s2)s1,,CC(C)=O,,,,test
US20140288052A1,COC(=O)c1cc(Cl)nn2cc(-c3ccccc3C(F)(F)F)nc12>>COC(=O)c1ccnn2cc(-c3ccccc3C(F)(F)F)nc12,[Pd],CCOC(C)=O,,CCN(CC)CC,,test
US05726306,COc1cc(OC)c(C(=O)c2cc(Cl)ccc2NC(C)=O)c(OC)c1>>COc1cc(OC)c(C(=O)c2cc(Cl)ccc2N)c(OC)c1,,CCO,,Cl,,test
US20140364411A1,CC(C)c1cc(N)n(-c2cnn(CCO)c2)n1.O=C(Cl)OCC(Cl)(Cl)Cl>>CC(C)c1cc(NC(=O)OCC(Cl)(Cl)Cl)n(-c2cnn(CCO)c2)n1,,CCOC(C)=O,,[Na+].[OH-],,test
US20050009815A1,CCCc1cc(OC)c2cc(C(=O)OCC)ccc2n1>>CCCc1cc(OC)c2cc(C(=O)O)ccc2n1,,CCO,O,Cl,[K+].[OH-],test
US20030027847A1,CNC(=O)C(c1ccc(F)cc1)c1ccc(F)cc1>>CNCC(c1ccc(F)cc1)c1ccc(F)cc1,,C1CCOC1,,CCOCC,FB(F)F,test
US20050038072A1,O=C(N=C=S)c1ccccc1.O=C1CCNCC1C(c1ccccc1)c1ccccc1>>O=C(NC(=S)N1CCC(=O)C(C(c2ccccc2)c2ccccc2)C1)c1ccccc1,,ClCCl,,CCN(CC)CC,Cl,test
US20060281695A1,Nc1ccc(Cl)cc1Oc1ccc(Cl)cc1Cl.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=S(=O)(Nc1ccc(Cl)cc1Oc1ccc(Cl)cc1Cl)C(F)(F)F,,ClCCl,,O,,test
US04931436,CCN(CC)CCC1CCNCC1.O=C1Nc2cccnc2N(C(=O)Cl)c2ccccc21>>CCN(CC)CCC1CCN(C(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1,,CCOC(C)=O,,,,test
US20070027321A1,CCI.Oc1cncc(Cl)c1>>CCOc1cncc(Cl)c1,,O,,CN(C)C=O,[H-].[Na+],test
US05223505,Nc1nccc(Cl)n1.c1ccc2c(c1)CCN2>>Nc1nccc(N2CCc3ccccc32)n1,,C1COCCO1,,,,test
US20130252972A1,Brc1cccnc1.CC(=O)c1c(-c2ccc(Cl)cc2)noc1-c1ccccc1>>CC(O)(c1cccnc1)c1c(-c2ccc(Cl)cc2)noc1-c1ccccc1,,C1CCOC1,CCOCC,[Li]CCCC,,test
US04829067,CC[N+](=O)[O-].COC(=O)c1cccc(C=O)c1O>>COC(=O)c1cccc(C=C(C)[N+](=O)[O-])c1O,,Cc1ccccc1,,C1CCNCC1,,test
US20090023795A1,COC(Cn1ncc2cc(Oc3ccc(F)cc3CNC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)ccc21)OC>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(F)ccc2Oc2ccc3c(cnn3CC=O)c2)cc1,,ClCCl,,C[Si](C)(C)I,,test
US20050107409A1,CN(C)C1CN(C(=O)c2ccc3c(Cl)ncnc3c2)C1.N=C(N)c1cccc(CN)c1>>CN(C)C1CN(C(=O)c2ccc3c(NCc4cccc(C(=N)N)c4)ncnc3c2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20030139409A1,COc1cccc2c1ccc1nc3cccc(C(=O)O)c3nc12>>O=C(O)c1cccc2nc3ccc4c(O)cccc4c3nc12,,ClCCl,,BrB(Br)Br,,test
US20150218096A1,O=C(Cl)C(=O)Cl.O=C(O)c1c(Cl)cccc1C1CCC1>>O=C(Cl)c1c(Cl)cccc1C1CCC1,CN(C)C=O,ClCCl,,,,test
US20100286390A1,CI.C[C@H]1[C@H](Nc2cnn(C3CCCCO3)c(=O)c2O)C[C@@H]2C[C@H]1C2(C)C>>COc1c(N[C@@H]2C[C@@H]3C[C@H]([C@H]2C)C3(C)C)cnn(C2CCCCO2)c1=O,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20080214526A1,C=CCNC(=O)C[C@@H](C)C(=O)OC(C)(C)C>>C=CCNC(=O)C[C@@H](C)C(=O)O,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20120053053A1,COC(=O)c1nc(C2CC2)nc(Cl)c1Cl.N>>COC(=O)c1nc(C2CC2)nc(N)c1Cl,,ClC(Cl)Cl,,CO,,test
US20120077828A1,Cc1cccc(CC(=O)O)c1.Cn1nc(-c2ccc3c(c2)CCN3)c2c(N)ncnc21>>Cc1cccc(CC(=O)N2CCc3cc(-c4nn(C)c5ncnc(N)c45)ccc32)c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05859007,Cc1nn(C(=O)OC(C)(C)C)c2ccccc12.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)n1nc(CBr)c2ccccc21,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20150225412A1,CC(C)(C=O)NC(=O)OC(C)(C)C.C[C@H](N(Cc1ccc2c(c1)nc(NC(=O)c1ccc(Cl)cc1)n2C1CCCN(C(=O)CC#N)C1)C(=O)OCc1ccccc1)C(C)(C)C>>C[C@H](N(Cc1ccc2c(c1)nc(NC(=O)c1ccc(Cl)cc1)n2C1CCCN(C(=O)C(C#N)=CC(C)(C)NC(=O)OC(C)(C)C)C1)C(=O)OCc1ccccc1)C(C)(C)C,,C1COCCO1,,C1CCNCC1,,test
US20110118251A1,Cc1nn(-c2ncccc2Cl)cc1C=O.FC1(F)COC2(CCNCC2)c2sc(Cl)cc21>>Cc1nn(-c2ncccc2Cl)cc1CN1CCC2(CC1)OCC(F)(F)c1cc(Cl)sc12,CC(=O)O,ClCCCl,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070015783A1,COc1ccc(S(=O)(=O)Cl)cc1.O=C1C(Cc2ccccc2)NC2(CCNCC2)N1Cc1ccccc1>>COc1ccc(S(=O)(=O)N2CCC3(CC2)NC(Cc2ccccc2)C(=O)N3Cc2ccccc2)cc1,,ClCCl,,CCN(CC)CC,O=C([O-])[O-].[Na+].[Na+],test
US05952306,C1CCOC1.COC(=O)CCBr.c1cnc2ncccc2c1>>COC(=O)CCCc1ccnc2ncccc12,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20080234255A1,CCC1CN(C2CCCC2)c2nc(Cl)ncc2N(CC)C1=O.COc1cc(C(=O)O)ccc1N>>CCC1CN(C2CCCC2)c2nc(Nc3ccc(C(=O)O)cc3OC)ncc2N(CC)C1=O,Cl,O,,CCO,,test
US20080249093A1,CC(O)C(F)(F)F.COC(=O)c1cnc(Cl)cc1C(F)(F)F>>CC(Oc1cc(C(F)(F)F)c(C(=O)O)cn1)C(F)(F)F,,C1CCOC1,CCOC(C)=O,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20130072492A1,FC(F)(F)CCBr.N#Cc1n[nH]c2ncccc12>>N#Cc1nn(CCC(F)(F)F)c2ncccc12,,CCOC(C)=O,O,CC#N,O=C([O-])[O-].[K+].[K+],test
US04426385,Cc1cc([N+](=O)[O-])cc(C)c1Oc1ccc(Cl)c2c1CCCC2>>Cc1cc(N)cc(C)c1Oc1ccc(Cl)c2c1CCCC2,[Pt],Cc1ccccc1,,[H][H],,test
US20060106029A1,Cl.O=C(c1cccc(Cl)c1F)N1CCN(Cc2cccc(Nc3nccs3)n2)CC1>>Cl.O=C(c1cccc(Cl)c1F)N1CCN(Cc2cccc(Nc3nccs3)n2)CC1,,CCO,,,,test
US04197240,COCc1cc(C(N)C(=O)O)ccc1O.O=C(Cl)OCc1ccccc1>>COCc1cc(C(NC(=O)OCc2ccccc2)C(=O)O)ccc1O,,O,,[Na+].[OH-],,test
US20150152131A1,CC1CC(Oc2ccccc2)C(O)O1.CON>>CON=CC(CC(C)O)Oc1ccccc1,,CCN(CC)CC,,CO,Cl,test
US20100267820A1,CC(C)CCCC(C)CC([PH3+])Br.Cc1c(C)c2c(c(C)c1O[Si](C)(C)C(C)(C)C)CCC(C)(C=O)O2>>Cc1c(C)c2c(c(C)c1O[Si](C)(C)C(C)(C)C)CCC(C)(C=CCC(C)CCCC(C)C)O2,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04620868,CC(C)(C)NS(=O)(=O)c1sc([Si](C)(C)C)cc1C(F)=C(F)Cl>>NS(=O)(=O)c1sccc1C(F)=C(F)Cl,,O,,O=S(=O)(O)C(F)(F)F,,test
US20080319114A1,C[C@@H]1OC(=O)[C@H](C)OC1=O.C[C@@H]1OC(=O)[C@H](C)OC1=O.O=C1COC(=O)C(CCCCNC(=O)OCc2ccccc2)N1.O=C1COC(=O)C(CCCCNC(=O)OCc2ccccc2)N1>>C[C@H](O)C(=O)O.N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O.O=C(O)CO,,ClC(Cl)Cl,,,,test
US20150232465A1,C[C@H](N)CO.O=[N+]([O-])c1ccccc1F>>C[C@@H](CO)Nc1ccccc1[N+](=O)[O-],,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20130029973A1,COC(=O)[C@@H]1CC[C@@H](N(C(=O)OC(C)(C)C)C(C)C)CC1.Cl>>COC(=O)[C@@H]1CC[C@@H](NC(C)C)CC1.Cl,,CCOC(C)=O,,,,test
US20020193398A1,CCOC(=O)Cc1ccnc(N(CC(F)(F)c2ccccn2)C(=O)OC(C)(C)C)c1F>>CCOC(=O)Cc1ccnc(NCC(F)(F)c2ccccn2)c1F,,CCOC(C)=O,,Cl,,test
US20130211075A1,CNC1CC=C(c2ncc(Br)cc2C)CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>Cc1cc(Br)cnc1C1=CCC(N(C)C(=O)C(F)(F)F)CC1,CN(C)c1ccncc1,c1ccncc1,,CCN(CC)CC,O,test
US20140206681A1,O=C(NCc1nccnc1Cl)[C@H]1CC[C@@H]2COC(=O)N2C1>>O=C1OC[C@@H]2CC[C@@H](c3ncc4c(Cl)nccn34)CN12,,CC#N,,O=P(Cl)(Cl)Cl,O=C([O-])O.[Na+],test
US05547960,C=CCC1CC2(Cc3ccc(=O)[nH]c31)OCCO2.CI>>C=CCC1CC2(Cc3ccc(OC)nc31)OCCO2,,ClC(Cl)Cl,,,,test
US20070082912A1,CC(=O)CCC(=O)c1cc(Br)ccc1OCc1ccc(F)cc1.Cc1ccc(N)cc1C(=O)O>>Cc1ccc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2)cc1C(=O)O,,CCOC(C)=O,CN1CCCC1=O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20050245530A1,CC(C)(C)OC(=O)Nc1cc(Oc2ccc(N)cc2F)ncn1.O=C(O)CC(=O)Nc1ccc(F)cc1>>CC(C)(C)OC(=O)Nc1cc(Oc2ccc(NC(=O)CC(=O)Nc3ccc(F)cc3)cc2F)ncn1,,CO,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20150038528A1,COC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O.NC[C@H](NC(=O)OCc1ccccc1)C(=O)O>>N#Cc1nc(C(=O)NC[C@H](NC(=O)OCc2ccccc2)C(=O)O)c(O)c2ccc(Oc3ccccc3)cc12,,COCCO,,C[O-].[Na+],,test
US04952722,CCC(=O)OC(=O)CC.O=C1C=C(O)CC(c2ccc3c(c2)CCCC3)C1>>CCC(=O)C1=C(O)CC(c2ccc3c(c2)CCCC3)CC1=O,,CN(C)C=O,,[H-].[Na+],,test
US20080227779A1,CCc1ccc(Nc2noc3c(C(=O)O)c(Cl)ccc23)cc1.Nc1cncnc1>>CCc1ccc(Nc2noc3c(C(=O)Nc4cncnc4)c(Cl)ccc23)cc1,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20070213371A1,Cn1nnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)Cc2cc(C(F)(F)F)ccc2C(=O)CC2CCCC2)n1>>Cn1nnc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)Cc2cc(C(F)(F)F)ccc2C(O)CC2CCCC2)n1,,CO,,[BH4-].[Na+],,test
US06355800B1,CC(=O)N1CCNCC1.[N-]=C=O>>CC(=O)N1CCN(C(N)=O)CC1,,O,,Cl,,test
US04012513,Clc1cc(Cl)nc(Cl)n1.NNc1ccccc1>>NN(c1ccccc1)c1cc(Cl)nc(Cl)n1,,CCO,O,CC(=O)[O-].[Na+],,test
US20150236279A1,CCN(CC)C(=O)c1cccnc1Br.Cc1cccc(C)c1B(O)O>>CCN(CC)C(=O)c1cccnc1-c1c(C)cccc1C,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US05324837,CC(=O)CNC(=O)C(F)(F)F.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>Cc1cnc(C(F)(F)F)s1,,c1ccccc1,,,,test
US06166006,Cc1ccc(-c2cccc(/C=C/C(=O)Nc3ccc(CCl)cc3)c2)cc1.OC1CCCNC1>>Cc1ccc(-c2cccc(/C=C/C(=O)Nc3ccc(CN4CCCC(O)C4)cc3)c2)cc1,,CN(C)C=O,,O,,test
US20130210809A1,C1COCCN1.COc1ccc(Cn2cc(C(=O)N(C)OC)c(Cl)n2)cc1>>COc1ccc(Cn2cc(C(=O)N(C)OC)c(N3CCOCC3)n2)cc1,,CN1CCCC1=O,,CCOC(C)=O,,test
US20120277207A1,CC(=O)C1CN(C(=O)/C=C/c2cnc3c(c2)CCC(=O)N3)C1.CCON>>CCO/N=C(/C)C1CN(C(=O)/C=C/c2cnc3c(c2)CCC(=O)N3)C1,,CO,ClCCl,Cl,,test
US20130072535A1,CI.COC(=O)C(Cc1ccc(Cl)cc1Cl)=NO>>CON=C(Cc1ccc(Cl)cc1Cl)C(=O)OC,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US06077841,CCCc1nn(C)c(C(N)=O)c1N.CCOc1cccc2cc(C(=O)Cl)oc12>>CCCc1nn(C)c(C(N)=O)c1NC(=O)c1cc2cccc(OCC)c2o1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20010021718A1,C=CC[C@H](CC(=O)CC(C)(C)C)C(=O)NC(CO)C(=O)[O-].CCN(CC)CC.CC[N+](CC)(CC)S(=O)(=O)NC(=O)OC>>C=CC[C@H](CC(=O)CC(C)(C)C)C1=N[C@H](C(=O)OCC)CO1,,C1CCOC1,,Cl,,test
US20120225854A1,BrC(Br)(Br)Br.COc1cc(CO)ccn1>>COc1cc(CBr)ccn1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090018132A1,Cn1cc2cc(C(F)(F)F)cc(COCC3(c4ccc(F)cc4)CCN(C(=O)OC(C)(C)C)CC3)c2n1>>Cn1cc2cc(C(F)(F)F)cc(COCC3(c4ccc(F)cc4)CCNCC3)c2n1,,O=C(O)C(F)(F)F,,,,test
US05500453,CCCC[B-](c1ccccc1)(c1ccccc1)c1ccccc1.C[S+](C)CC(=O)c1ccccc1>>CCCC[B-](c1ccccc1)(c1ccccc1)c1ccccc1.C[S+](C)Cc1ccccc1,,O,,[Cl-].[Li+],,test
US05116402,CCCCO.OC(O)C(Cl)(Cl)Cl.c1ccccc1>>CCCCOC(OCCCC)C(Cl)(Cl)Cl,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20080132546A1,COC(=O)C(Cl)C(=O)C(C)(OC)OC.NC(N)=S>>COC(=O)c1sc(N)nc1C(C)=O,,CCO,,,,test
US05622953,COC(=O)c1cccc(O[SiH](C)C)c1C(C)(C)C.Cc1cc(C)on1>>Cc1cc(CC(=O)c2cccc(O[SiH](C)C)c2C(C)(C)C)on1,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US20100249119A1,Cc1ccc(NC(=O)OC(C)(C)C)cc1N.N#CSc1nc(Cl)ncc1[N+](=O)[O-]>>Cc1ccc(NC(=O)OC(C)(C)C)cc1Nc1ncc([N+](=O)[O-])c(SC#N)n1,,C1CCOC1,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20150299189A1,O=[N+]([O-])c1ccc2c(ccn2CCc2ccccc2)c1>>Nc1ccc2c(ccn2CCc2ccccc2)c1,[Pd],C1CCOC1,,,,test
US20110059118A1,Brc1cnc2[nH]ccc2n1.OB(O)c1cccnc1F>>c1cnc2cc[nH]c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20100280030A1,CN(C)CCO.Cc1ccc2oc(=O)n(Cc3cccc(-c4ncc(O)cn4)c3)c2n1>>Cc1ccc2oc(=O)n(Cc3cccc(-c4ncc(OCCN(C)C)cn4)c3)c2n1,,CN(C)C=O,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070232583A1,CC(C)(CO)NS(=O)(=O)c1cccc(Br)c1.CCCC[Sn](CCCC)(CCCC)c1cn(-c2cc(C(F)(F)F)cc(-c3ccc(C(F)(F)F)cc3)n2)cn1>>CC(C)(CO)NS(=O)(=O)c1cccc(-c2cn(-c3cc(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)n3)cn2)c1,,Cc1ccccc1,,CCCCCCC,,test
US06130241,C=CCCCCCCBr.O=C1NC(=O)C2CC12>>C=CCCCCCCN1C(=O)C2CC2C1=O,,CN(C)C=O,O,[H-].[Na+],,test
US20060182714A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@H](CCCCNC(=O)COCCOCCOCCN=[N+]=[N-])NC(=O)COCCOCCOCCN=[N+]=[N-]>>COC(=O)[C@H](CCCCNC(=O)COCCOCCOCCNC(=O)OC(C)(C)C)NC(=O)COCCOCCOCCNC(=O)OC(C)(C)C,[Pd],CCOC(C)=O,,,,test
US20130023541A1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.CC(C)OC(=O)c1cccnc1Cl>>CC(C)OC(=O)c1cccnc1N1CC[C@@H](NC(=O)OC(C)(C)C)C1,,C1CCOC1,,CCN(CC)CC,,test
US20080312226A1,N=C(N)c1ccsc1.SC(Cl)(Cl)Cl>>Clc1nc(-c2ccsc2)ns1,,ClCCl,O,Cl,[Na+].[OH-],test
US20070219234A1,C/C(=C(\C#N)C(N)=S)N1CCCCC1.COC(OC)N(C)C>>N#Cc1c(N2CCCCC2)cc[nH]c1=S,,Cc1ccccc1,,[Na+].[OH-],,test
US20110319394A1,CC1(C)C(=O)N(c2ccc(O)cc2)c2ncccc21.Cn1c(S(C)(=O)=O)nc2cccnc21>>Cn1c(Oc2ccc(N3C(=O)C(C)(C)c4cccnc43)cc2)nc2cccnc21,,CN(C)C=O,CO,[H-].[Na+],,test
US20090111807A1,CN1C(=O)C(C)(C)Nc2ccc(Br)c(CO)c21.CS(=O)(=O)Cl>>CN1C(=O)C(C)(C)Nc2ccc(Br)c(CCl)c21,,ClCCl,O,CCN(CC)CC,CCOC(C)=O,test
US20090036493A1,CC(=O)OC(C)=O.NCc1ccc2c(c1)ncn2-c1cccc(-c2nccs2)c1>>CC(=O)NCc1ccc2c(c1)ncn2-c1cccc(-c2nccs2)c1,,ClCCl,,,,test
US20150087646A1,CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)N=C=O)c1F.CC(C)(C)OC(=O)NNc1ccc(Cl)cc1>>CC(C)(C)C(=O)NCc1ccc(Cl)c(-c2nn(-c3ccc(Cl)cc3)c(=O)[nH]2)c1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100004269A1,C[Si](C)(C)c1ccc(Nc2nc(Cl)c(F)cc2C(=O)O)c(F)c1.ClCCl>>COC(=O)c1cc(F)c(Cl)nc1Nc1ccc([Si](C)(C)C)cc1F,,CN(C)C=O,ClCCl,O=C(Cl)C(=O)Cl,,test
US20070099927A1,CC(=O)OCCn1c(Cl)cnc(NCCC2CCCCN2C(=O)OC(C)(C)C)c1=O>>CC(=O)OCCn1c(Cl)cnc(NCCC2CCCCN2)c1=O,,ClCCl,,Cc1ccccc1,O=C(O)C(F)(F)F,test
US20140194383A1,COC(=O)Cc1cc(=O)oc2c(O)c(O)ccc12>>O=C(O)Cc1cc(=O)oc2c(O)c(O)ccc12,,CC(=O)O,,Cl,,test
US20110212053A1,CC(C)(C#N)c1ccc(Cc2c([N+](=O)[O-])cnc3ccc(B4OC(C)(C)C(C)(C)O4)cc23)cc1.COc1cccc(Br)n1>>COc1cccc(-c2ccc3ncc([N+](=O)[O-])c(Cc4ccc(C(C)(C)C#N)cc4)c3c2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20130005705A1,COC(=O)c1c(Br)cccc1CBr.NCCc1ccc2ccccc2n1>>O=C1c2c(Br)cccc2CN1CCc1ccc2ccccc2n1,,CCO,,,,test
US04985428,NC(CO)(CO)CO.O=C(O)CCCNC(=O)c1cc(Br)no1>>NC(CO)(CO)CO.O=C(O)CCCNC(=O)c1cc(Br)no1,,CCO,,,,test
US20110092531A1,BrP(Br)Br.Cc1cc(CO)ccc1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>Cc1cc(CBr)ccc1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,ClCCl,ClCCl,,,test
US06251912B1,Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1.O=C(O)C#CCN1CCOCC1>>O=C(C#CCN1CCOCC1)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1,,C1CCOC1,c1ccncc1,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20090215766A1,CCCCO.Nc1ccnc(Cl)c1>>CCCCOc1cc(N)ccn1,,O,,[Na+].[OH-],,test
US20090247550A1,Nc1nc(C(F)(F)F)c(Br)nc1Br.OB(O)c1ccc(Cl)cc1>>Nc1nc(C(F)(F)F)c(Br)nc1-c1ccc(Cl)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US05968982,Clc1ccc(CCCCCBr)cc1.NC(N)=S>>SCCCCCc1ccc(Cl)cc1,,CCO,,Cl,N,test
US20160068512A1,CS(=O)(=O)NCCOc1nc(NC2CCNCC2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2n1.O=C(O)c1ccc(S(=O)(=O)Cl)cc1>>CS(=O)(=O)NCCOc1nc(NC2CCN(S(=O)(=O)c3ccc(C(=O)O)cc3)CC2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2n1,,ClCCl,,CCN(CC)CC,,test
US04288596,CCOC(=O)c1cc2[nH]c3ccccc3c2o1.CI>>CCOC(=O)c1cc2c(o1)c1ccccc1n2C,,CN(C)C=O,,[H-].[Na+],,test
US20100292279A1,C#C[Mg]Br.O=C(C1CC1)C1CC1>>C#CC(O)(C1CC1)C1CC1,,CCOCC,,Cl,[Cl-].[NH4+],test
US20080153817A1,CCC[Mg]Cl.O=Cc1ccc(C(F)(F)F)cc1>>CCCC(O)c1ccc(C(F)(F)F)cc1,,C1CCOC1,,,,test
US20100137282A1,CCOC(=O)CSc1cnc(Cl)nc1Cl.N>>CCOC(=O)CSc1cnc(Cl)nc1N,,CN(C)C=O,,CC(C)O,,test
US05093353,C1CCNC1.CCCc1c(O)ccc(C(C)=O)c1O.Cc1ccccc1>>C=CCCC1(CCC=C)CC(=O)c2ccc(O)c(CCC)c2O1,,Cc1ccccc1,,,,test
US20160039745A1,Brc1ccc2cn[nH]c2c1.FC(F)Cl>>FC(F)n1cc2ccc(Br)cc2n1,,CN(C)C=O,,[H-].[Na+],,test
US20130165390A1,CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B1OB([C@H](CC(C)C)NC(=O)CNC(=O)c2cc(Cl)ccc2Cl)OB([C@H](CC(C)C)NC(=O)CNC(=O)c2cc(Cl)ccc2Cl)O1.O=C(O)C(O)(c1ccccc1)c1ccccc1>>CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B1OC(=O)C(c2ccccc2)(c2ccccc2)O1,,CCOC(C)=O,,,,test
US04208502,C1COCCO1.O=C(Cl)c1c(Cl)c(Cl)c(C(=O)Cl)c(Cl)c1Cl.OCCO.c1ccncc1>>O=C(OCCO)c1c(Cl)c(Cl)c(C(=O)OCCO)c(Cl)c1Cl,,c1ccncc1,,C1CCOC1,,test
US20130053364A1,CCOC(=O)c1c(C)ccc(Br)c1O.COS(=O)(=O)OC>>CCOC(=O)c1c(C)ccc(Br)c1OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140065103A1,COC(=O)c1sc(C#CC(C)(C)C)cc1N(Cc1ccnn1C)C(=O)[C@@H]1CC[C@@H](C)CC1>>C[C@@H]1CC[C@@H](C(=O)N(Cc2ccnn2C)c2cc(C#CC(C)(C)C)sc2C(=O)O)CC1,,CO,,[Na+].[OH-],,test
US20110053916A1,N#CCc1ccc(-c2ncc([N+](=O)[O-])c(Nc3cc(C4CC4)[nH]n3)n2)cc1>>N#CCc1ccc(-c2ncc(N)c(Nc3cc(C4CC4)[nH]n3)n2)cc1,[Fe],O,,CCO,[Cl-].[NH4+],test
US06573289B1,CC(C)(C)C(=O)OCI.CC(C)C(O)(c1ccc2cc(O)ccc2c1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>CC(C)C(O)(c1ccc2cc(OCOC(=O)C(C)(C)C)ccc2c1)c1c[nH]cn1,,CCOC(C)=O,O,CN(C)C=O,[H-].[Na+],test
US20120101064A1,COC(=O)c1cccnc1Br.OB(O)c1cncc2ccccc12>>COC(=O)c1ccncc1-c1cncc2ccccc12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20070244125A1,CC(C)CS(=O)(=O)[O-].CCOC(=O)c1cc2cc(C(=O)N3CCCC(N(C)C)C3)ccc2[nH]1>>CCOC(=O)c1cc2cc(C(=O)N3CCCC(N(C)C)C3)ccc2n1C(C)C,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05264578,C=CC(=O)OCC.Sc1ccc(Br)cc1>>CCOC(=O)CCSc1ccc(Br)cc1,,ClCCl,,CCN(CC)CC,[Na+].[OH-],test
US20160264552A1,NC1CC2(C1)CC(Nc1ncc(Cl)c(-c3cn(S(=O)(=O)c4ccccc4)c4ccccc34)n1)C2.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>O=C(NC1CC2(C1)CC(Nc1ncc(Cl)c(-c3cn(S(=O)(=O)c4ccccc4)c4ccccc34)n1)C2)c1ccc([N+](=O)[O-])cc1,,ClCCl,,CCN(CC)CC,,test
US20100081673A1,CCN.O=Cc1cc(C(F)(F)F)ccc1Br>>CCNCc1cc(C(F)(F)F)ccc1Br,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20110150833A1,CN(C)CCOc1cc(Br)ccc1[N+](=O)[O-]>>CN(C)CCOc1cc(Br)ccc1N,,CCO,,,,test
US20060094708A1,CC(C)(C)OC(=O)CC[C@H](CO)NC(=O)OC(C)(C)C.II>>CC(C)(C)OC(=O)CC[C@H](CI)NC(=O)OC(C)(C)C,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06011159,CCC(=O)c1ccc(Br)cc1O.CS(=O)(=O)Cl>>CCC(=O)c1ccc(Br)cc1OS(C)(=O)=O,,ClCCl,,CCN(CC)CC,Cl,test
US20140179670A1,C[C@@H](O)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C.O=c1ccn(-c2cccc(C(F)(F)F)c2)c(=O)[nH]1>>C[C@H](CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)n1c(=O)ccn(-c2cccc(C(F)(F)F)c2)c1=O,,C1CCOC1,O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090227588A1,O=C(NCCC(c1ccccc1)c1ccccc1)c1ccc(N2N=C(c3cccnc3)CC2(O)C(F)(F)F)nc1>>O=C(NCCC(c1ccccc1)c1ccccc1)c1ccc(-n2nc(-c3cccnc3)cc2C(F)(F)F)nc1,,CC(=O)O,,,,test
US20080300275A1,CC(C)(C)OC(=O)CCOCCc1ccc2ccccc2c1>>O=C(O)CCOCCc1ccc2ccccc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06015774,N#CC(N)c1ccc(F)cc1.O=S(=O)(O)O>>NC(=O)C(N)c1ccc(F)cc1,,O,,N,,test
US20120142714A1,C[C@@H](COc1noc(CO)c1F)NC(=O)OC(C)(C)C>>C[C@@H](COc1noc(C=O)c1F)NC(=O)OC(C)(C)C,,CC#N,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20100197654A1,CC(C)(C)OC(=O)N1C[C@H](F)C[C@H]1C(=O)Nc1cnccn1>>O=C(Nc1cnccn1)[C@@H]1C[C@@H](F)CN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04262005,CCOC(=O)Cl.Clc1ccc(N=C2NCCN2)c(Cl)c1>>CCOC(=O)N1CCNC1=Nc1ccc(Cl)cc1Cl,,C1CCOC1,,[H-].[Na+],,test
US20120172448A1,C=COCC.C[C@H]([C@H](C(=O)Nc1cc(C(O)C2(C(=O)OC(C)(C)C)CC2)ccc1Cl)c1ccc(Cl)cc1)C(F)(F)F>>C=COC(c1ccc(Cl)c(NC(=O)[C@H](c2ccc(Cl)cc2)[C@@H](C)C(F)(F)F)c1)C1(C(=O)OC(C)(C)C)CC1,,ClCCl,,,,test
US20030008849A1,CC#CCOc1ccc(S(=O)(=O)NC(C(=O)OC)c2ccc(OCCN3CCCC3)cc2)cc1>>CC#CCOc1ccc(S(=O)(=O)NC(C(=O)O)c2ccc(OCCN3CCCC3)cc2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20120010247A1,Cc1cc(F)ncc1C(=O)O.OCC1CC1>>Cc1cc(F)ncc1C(=O)OCC1CC1,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,Cl,test
US20040157886A1,Nc1ccc2[nH]c(=O)[nH]c2c1.O=C(O)C(=O)N1CCC(Cc2ccc(F)cc2)CC1>>O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)C(=O)N1CCC(Cc2ccc(F)cc2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090124625A1,C(#Cc1ccccn1)CCn1nc2ccccc2n1.Cl>>C(#Cc1ccccn1)CCn1nc2ccccc2n1.Cl,,C1COCCO1,,,,test
US20120126175A1,Brc1ccc2ccc3cccc4ccc1c2c34.CC(C)(C)[Si](C)(C)OCc1cc(CO[Si](C)(C)C(C)(C)C)cc(B(O)O)c1>>CC(C)(C)[Si](C)(C)OCc1cc(CO[Si](C)(C)C(C)(C)C)cc(-c2ccc3ccc4cccc5ccc2c3c45)c1,Cl[Pd]Cl,C1CCOC1,O,CCOC(C)=O,,test
US20020037907A1,COC(=O)c1ccc(N2CCC(C(OC)OC)CC2)cc1>>COC(OC)C1CCN(c2ccc(C(=O)O)cc2)CC1,,CO,,Cl,,test
US04294960,CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=CCS[C@H]12)c1csc(NC=O)n1>>CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=CCS[C@H]12)c1csc(N)n1,,CO,,Cl,,test
US20090088322A1,COC(=O)c1cc(Cl)nc(Cl)n1.N>>COC(=O)c1cc(N)nc(Cl)n1,,CS(C)=O,,,,test
US20100041642A1,C=Cc1ccc(Br)nc1>>CCc1ccc(Br)nc1,O=[Pt]=O,CCO,,[H][H],,test
US20080114002A1,CS(=O)(=O)c1ccc(F)c(C(F)(F)F)c1.O=C(O)Cc1ccc(Cl)cc1O>>CS(=O)(=O)c1ccc(Oc2cc(Cl)ccc2CC(=O)O)c(C(F)(F)F)c1,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090291978A1,CCOC(=O)CCc1ccc2[nH]c(C(=O)NCCCCCCC(=O)NOC3CCCCO3)cc2c1>>O=C(O)CCc1ccc2[nH]c(C(=O)NCCCCCCC(=O)NOC3CCCCO3)cc2c1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US05081271,C[Si](C)(C)c1cccc([Si](C)(C)C)c1.O=[N+]([O-])O>>C[Si](C)(C)c1cccc([N+](=O)[O-])c1,,CC(=O)OC(C)=O,,ClCCl,O=C([O-])[O-].[K+].[K+],test
US05231102,CC(C)(CCI)C(=O)[O-].O=C(Cc1ccccc1)N[C@H]1C[C@H](C(=O)O)Nc2cc(Cl)cc(Cl)c21>>CC(C)(C)C(=O)OCOC(=O)[C@H]1C[C@H](NC(=O)Cc2ccccc2)c2c(Cl)cc(Cl)cc2N1,,C1CCOC1,,CCN(CC)CC,,test
US20110105499A1,CCn1c(=O)c(=O)[nH]c2cnn(-c3ccc(F)cc3F)c21.O=P(Cl)(Cl)Cl>>CCn1c(=O)c(Cl)nc2cnn(-c3ccc(F)cc3F)c21,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US20110263564A1,ON=C1CCOc2ccc(-c3cccc(C(F)(F)F)c3)nc21>>NC1CCOc2ccc(-c3cccc(C(F)(F)F)c3)nc21,[Zn],CC(=O)O,,,,test
US20150218093A1,COc1cc(N2CCC(Oc3ccc(-c4ccccc4)cc3)C2=O)ccc1OCOCC[Si](C)(C)C>>COc1cc(N2CCC(Oc3ccc(-c4ccccc4)cc3)C2=O)ccc1O,,ClCCl,,C1COCCO1,Cl,test
US20110003833A1,CCOC(=O)C1(Cc2cccc(Nc3ccnn3C(C)(C)C)n2)CCN(C(=O)c2cccc(Cl)c2F)CC1>>CCOC(=O)C1(Cc2cccc(Nc3cc[nH]n3)n2)CCN(C(=O)c2cccc(Cl)c2F)CC1,,O=CO,,,,test
US20110144097A1,CCOC(=O)c1cc(C2CC2)n[nH]1.O=C1CCC(=O)N1Cl>>CCOC(=O)c1[nH]nc(C2CC2)c1Cl,,CN(C)C=O,,,,test
US20100056507A1,CC1(C)CCC(C)(C)c2cc(-c3nnc(CCc4ccc(N)cc4)o3)ccc21.O=C(Cl)C1CCC1>>CC1(C)CCC(C)(C)c2cc(-c3nnc(CCc4ccc(NC(=O)C5CCC5)cc4)o3)ccc21,,C1CCOC1,,CCN(CC)CC,,test
US20130131018A1,COCCl.O=Cc1cccc(O)c1O>>COCOc1c(O)cccc1C=O,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04087611,COCCn1cc(-c2ccccc2)[nH]c1=O.O=C(Cl)c1ccccc1>>COCCn1cc(-c2ccccc2)n(C(=O)c2ccccc2)c1=O,,Cc1ccccc1C,,CCCCN(CCCC)CCCC,,test
US20040063580A1,CI.NCCCO.S=C=S>>CSC(=S)NCCCO,,c1ccncc1,,CCN(CC)CC,Cl,test
US06147214,Cl.O=C(Nc1cccc(C=C[N+](=O)[O-])c1)c1ccccc1-c1ccc(C(F)(F)F)cc1>>Cl.NCCc1cccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)c1,[Pd],CCO,,,,test
US20080139639A1,CN(Cc1cc(Br)n(S(=O)(=O)c2cccc(Cl)c2)c1)C(=O)OC(C)(C)C.OB(O)c1ccccc1>>CN(Cc1cc(-c2ccccc2)n(S(=O)(=O)c2cccc(Cl)c2)c1)C(=O)OC(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US20090023725A1,Cc1ccc(C(=O)Nc2c(C)cnn2C)cc1B1OC(C)(C)C(C)(C)O1.Fc1ccc(-c2n[nH]c3cc(Br)ccc23)cc1>>Cc1ccc(C(=O)Nc2c(C)cnn2C)cc1-c1ccc2c(-c3ccc(F)cc3)n[nH]c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(C)O,,O=C([O-])O.[Na+],,test
US20140134235A1,Cc1cccc2cc(CNCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)c(N(CC3CC3)CC3CC3)nc12.Clc1ncnc(Cl)n1>>Cc1cccc2cc(CN(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)c3ncnc(Cl)n3)c(N(CC3CC3)CC3CC3)nc12,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20090281160A1,O=C(N[C@@H](Cc1ccccc1)C(=O)CCC(=O)N1CCC[C@H]1C(=O)OCc1ccccc1)c1ccccc1>>O=C(N[C@@H](Cc1ccccc1)C(=O)CCC(=O)N1CCC[C@H]1C(=O)O)c1ccccc1,[Pd],CCOC(C)=O,CO,[H][H],,test
US20110021516A1,Nc1ccc2c(c1)C[C@@]1(C2)C(=O)Nc2ncccc21.O=C1CCC(=O)N1I>>Nc1cc2c(cc1I)C[C@]1(C2)C(=O)Nc2ncccc21,,C1CCOC1,,,,test
US20110237527A1,COCOCC1O[C@@H](c2ccc(Cl)c(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)c2)[C@@H](OCOC)[C@@H](OCOC)[C@@H]1OCOC>>COCOCC1O[C@@H](c2ccc(Cl)c(CO)c2)[C@@H](OCOC)[C@H](OCOC)[C@@H]1OCOC,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040157886A1,Nc1ccc(Br)cc1.O=C(O)C(=O)N1CCC(Cc2ccccc2)CC1>>O=C(Nc1ccc(Br)cc1)C(=O)N1CCC(Cc2ccccc2)CC1,,CCOCC,,,,test
US20120115903A1,CCOC(=O)C(CC)C(=O)OC.CCOC(=O)c1cc2ccccc2n1C>>CCOC(=O)c1c(C(C)(C(=O)OCC)C(=O)OCC)c2ccccc2n1C,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20030134748A1,BrBr.Cc1c(-c2ccc(OC(F)(F)C(F)Br)cc2)csc1-c1nc(-c2c(F)cccc2Cl)nn1C>>Cc1c(-c2nc(-c3c(F)cccc3Cl)nn2C)sc(Br)c1-c1ccc(OC(F)(F)C(F)Br)cc1,,CC(=O)O,,O=C([O-])O.[Na+],,test
US20110306591A1,Clc1nc2ccccc2s1.NC1CC(Oc2nccnc2Cl)C1>>Clc1nccnc1OC1CC(Nc2nc3ccccc3s2)C1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,Cl,test
US20100305085A1,CCOC(=O)C(=CNNc1cc(N2CCOCC2)ncn1)n1ccnn1.Cl>>Cl.O=c1c(-n2ccnn2)c[nH]n1-c1cc(N2CCOCC2)ncn1,,CCO,CO,C[O-].[Na+],,test
US06300352B1,C[C@H](Oc1ccc(B(O)O)cc1)[C@H](O)CCc1cccnc1.NS(=O)(=O)c1cc(Br)cc(C(F)(F)F)c1>>C[C@H](Oc1ccc(-c2cc(C(F)(F)F)cc(S(N)(=O)=O)c2)cc1)[C@H](O)CCc1cccnc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US05273977,CS(=O)(=O)OS(C)(=O)=O.Nc1ccc(C#CCCN2CC=C(c3ccccc3)CC2)nc1>>CS(=O)(=O)Nc1ccc(C#CCCN2CC=C(c3ccccc3)CC2)nc1,,ClCCl,,CCN(CC)CC,,test
US04544562,CC1CC(=O)NN=C1c1ccc(N)cc1.COC(=O)CC(=O)Cl>>COC(=O)CC(=O)Nc1ccc(C2=NNC(=O)CC2C)cc1,,CC(C)=O,,,,test
US20090270402A1,N=C1NCCO1.O=C(CBr)c1ccc(F)cc1F>>Fc1ccc(-c2cn3c(n2)OCC3)c(F)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US04272540,BrCC1CC1.COc1ccc2c(c1)[C@]13CCN[C@H](C2)[C@]1(OC)CCC(=O)C3>>COc1ccc2c(c1)[C@]13CCN(CC4CC4)[C@H](C2)[C@]1(OC)CCC(=O)C3,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20150045356A1,Cl.O=C(OCCl)OC1CCCCC1.O=c1ccc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc2[nH]1>>Cl.O=C(OCn1c(=O)ccc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc21)OC1CCCCC1,,C1CCOC1,,[H-].[Na+],,test
US20130211075A1,CN(C)S(=O)(=O)Cl.Cc1c(C(=O)Nc2ccc(C3(C#N)CCNCC3)nc2)cnn1-c1ccc(C(F)(F)F)cn1>>Cc1c(C(=O)Nc2ccc(C3(C#N)CCN(S(=O)(=O)N(C)C)CC3)nc2)cnn1-c1ccc(C(F)(F)F)cn1,,O,,CCN(CC)CC,ClCCl,test
US20040106824A1,CO.Cl.N#CC(NCCc1cccs1)c1ccccc1Cl>>Cl.NC(=O)C(NCCc1cccs1)c1ccccc1Cl,,CCOC(C)=O,,,,test
US20050267149A1,CCCCCCNCc1ccccc1.O=C(Cl)CBr>>CCCCCCN(Cc1ccccc1)C(=O)CBr,,ClCCl,,CCN(CC)CC,,test
US20060052365A1,CC(C)(C)OC(=O)N[C@@H](CC1CCCC1)C(=O)NC1CCCN(C(=O)OCc2ccccc2)CC1O>>N[C@@H](CC1CCCC1)C(=O)NC1CCCN(C(=O)OCc2ccccc2)CC1O,,C1COCCO1,CO,,,test
US20090118305A1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.CNC(=O)c1n[nH]cc1Br>>CNC(=O)c1nn(C2CCN(C(=O)OC(C)(C)C)CC2)cc1Br,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080019915A1,O=C(Nc1cccc(-c2ccc(S(=O)(=O)O)cc2)n1)C1(c2ccc3c(c2)OCO3)CC1.O=S(Cl)Cl>>O=C(Nc1cccc(-c2ccc(S(=O)(=O)Cl)cc2)n1)C1(c2ccc3c(c2)OCO3)CC1,,O=P(Cl)(Cl)Cl,,CN(C)C=O,,test
US20090036448A1,Cc1nc(N[C@@H]2CC[C@H](N)CC2)cc(N(C)C)n1.O=C(Cl)Oc1ccc(Br)cc1>>Cc1nc(N[C@@H]2CC[C@H](NC(=O)Oc3ccc(Br)cc3)CC2)cc(N(C)C)n1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20110177302A1,C=C(C)C(=O)OC(C)OC1CCCCC1.C=Cc1ccc(OC)cc1.CC(=O)CC(C)C.CCC(C)(N=NC(C)(CC)C(=O)[O-])C(=O)[O-].CCCCCCC>>C=C(C)C(=O)OC(C)OC1CCCCC1.C=Cc1ccc(OC)cc1.CCOCCOCCOC,,CCCCCCC,,,,test
US05175157,COc1cc2c(cc1OC)CC(=O)N(CC1CCCN(CCc3ccc(OCc4ccccc4)c(OC)c3)C1)CC2>>COc1cc(CCN2CCCC(CN3CCc4cc(OC)c(OC)cc4CC3=O)C2)ccc1O,,CC(=O)O,,,,test
US20160083387A1,C=C1CC[C@H]2[C@H](CNCc3ccc(C(=O)c4ccccc4)cc3)[C@@H]([C@@]3(C)CC[C@H](OC(C)=O)C[C@@H]3COC(C)=O)CC[C@]12C>>C=C1CC[C@H]2[C@H](CNCc3ccc(C(=O)c4ccccc4)cc3)[C@@H]([C@@]3(C)CC[C@H](O)C[C@@H]3CO)CC[C@]12C,,CO,,[Na+].[OH-],,test
US20030096826A1,C1CCOC1.CON(C)C(=O)Cc1c(C)ccc2ccccc12>>CC(=O)Cc1c(C)ccc2ccccc12,,O,,,,test
US20120142705A1,Cc1ccc2c(c1)C(=O)C(=O)N2C(CC(C)C)C(=O)O.Nc1nccs1>>Cc1ccc2c(c1)C(=O)C(=O)N2C(CC(C)C)C(=O)Nc1nccs1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20040138222A1,Cc1ccc2c3c(ccc2n1)OC[C@H](COS(=O)(=O)c1ccc(Br)cc1)O3.Cn1cc(CCCN)c2cc(C#N)ccc21>>Cc1ccc2c3c(ccc2n1)OCC(CNCCCc1cn(C)c2ccc(C#N)cc12)O3,,CS(C)=O,,CCN(CC)CC,,test
US20090239949A1,CC(C)(C)OC(=O)N[C@@H](CCCNC(N)=O)C(=O)O>>NC(=O)NCCC[C@H](N)C(=O)O,,C1COCCO1,,Cl,,test
US20070265225A1,COC(=O)C(C)(C)CC[C@H](N[S@@](=O)C(C)(C)C)c1cc(F)cc(F)c1>>CC1(C)CC[C@@H](c2cc(F)cc(F)c2)NC1=O,,CO,,CCN(CC)CC,,test
US20120329818A1,COC(=O)C1(O)CCN(C(=O)OC(C)(C)C)CC1.COCCCl>>COCCOC1(C(=O)OC)CCN(C(=O)OC(C)(C)C)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20020042427A1,CN1CCC=CC1=O.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>CN1CCc2c[nH]cc2C1=O,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20130289031A1,CC1(C)Cn2c(nc(Cl)cc2=O)N1.Cc1ccc(S(=O)(=O)OCCOC(C)C)cc1>>CC(C)OCCN1c2nc(Cl)cc(=O)n2CC1(C)C,,CC#N,CCOC(C)=O,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20030069273A1,C1COCCN1.O=C(O)c1ccc(-n2nc(-c3ccccc3O)nc2-c2ccccc2O)cc1>>O=C(c1ccc(-n2nc(-c3ccccc3O)nc2-c2ccccc2O)cc1)N1CCOCC1,,C1CCOC1,,CCN(CC)CC,,test
US05861359,CCI.Cc1ccc(COc2ccc(-c3nn(C)c(OC(F)F)c3Cl)cc2)c(OC(C)C(=O)O)c1>>CCOC(=O)C(C)Oc1cc(C)ccc1COc1ccc(-c2nn(C)c(OC(F)F)c2Cl)cc1,,CC#N,,,,test
US20160159740A1,CCC(=O)OC(=O)CC.O=C(OCc1ccccc1)n1cc(CO)c2ccccc21>>CCC(=O)OCc1cn(C(=O)OCc2ccccc2)c2ccccc12,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20110275801A1,C1COCCN1.CCC(C)=O>>C=C(CC)N1CCOCC1,Cl[Ti](Cl)(Cl)Cl,CCCCC,,ClCCl,,test
US03949076,CC(=O)OC1c2ccccc2Oc2ccccc21.NCCn1ccnc1>>c1ccc2c(c1)Oc1ccccc1C2NCCn1ccnc1,,c1ccccc1,,,,test
US20070232612A1,CN1C[C@H]2[C@H](CCN2c2ccc(-c3ccc(-c4cnn(C(c5ccccc5)(c5ccccc5)c5ccccc5)c4)cc3)cc2)C1>>CN1C[C@H]2[C@H](CCN2c2ccc(-c3ccc(-c4cn[nH]c4)cc3)cc2)C1,,O=CO,,,,test
US20160090386A1,CCOC(=O)c1cc(-c2ccccc2)sc1N>>Nc1ccc(-c2ccccc2)s1,,CCO,,Cl,,test
US20150018345A1,CCc1cc([C@@H](C)NC)cc(C(F)(F)F)c1.Cc1ccccc1[C@@H]1NCCN2C(=O)CC[C@@H]12.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCc1cc([C@@H](C)N(C)C(=O)N2CCN3C(=O)CC[C@H]3[C@@H]2c2ccccc2C)cc(C(F)(F)F)c1,CN(C)c1ccncc1,CCOC(C)=O,,,,test
US04360690,CCOc1ccc(C2(C(=O)Cl)CC2(Cl)Cl)cc1.OCc1ccc(F)c(Oc2ccccc2)c1>>CCOc1ccc(C2(C(=O)OCc3ccc(F)c(Oc4ccccc4)c3)CC2(Cl)Cl)cc1,,Cc1ccccc1,O,Cl,c1ccncc1,test
US04803215,COC(CC(OC)OC)OC.NNc1c(S(=O)(=O)C(F)(F)F)cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl>>O=S(=O)(c1cnn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1-n1cccn1)C(F)(F)F,,CCO,,O=S(=O)(O)O,O=C([O-])[O-].[Na+].[Na+],test
US20160152616A1,C#CCBr.CC1(C)CCn2c(=O)[nH]c3cccc1c32>>C#CCn1c(=O)n2c3c(cccc31)C(C)(C)CC2,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20040038986A1,CCOC(CN)OCC.O=C(Cl)OCc1ccccc1>>CCOC(CNC(=O)OCc1ccccc1)OCC,,CCOC(C)=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20100210622A1,CCO/C=C(/C#N)C(=O)OCC.COc1ccc(NN)cc1>>CCOC(=O)c1cnn(-c2ccc(OC)cc2)c1N,,CCO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US04962115,CCI.CCOC(=O)N1CCC(OC)(OC)C(O)C1>>CCOC(=O)N1CCC(OC)(OC)C(OCC)C1,,CN(C)C=O,,[H-].[Na+],,test
US20100069368A1,FC(F)(F)c1ccc(Cl)nc1.c1ccc2c(C3CCNCC3)c[nH]c2c1>>FC(F)(F)c1ccc(N2CCC(c3c[nH]c4ccccc34)CC2)nc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150119394A1,Cc1ccc(S(=O)(=O)OC[C@@H]2CN(Cc3ccccc3)CCO2)cc1.Oc1ccc(Br)cc1>>Brc1ccc(OC[C@@H]2CN(Cc3ccccc3)CCO2)cc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US04979961,CI.NCCS.O=[N+]([O-])c1ccc(F)cc1>>CSCCNc1ccc([N+](=O)[O-])cc1,,CCN(CC)CC,O,Cl,[Na+].[OH-],test
US20140364413A1,CCOP(=O)(Cc1ccc2ccccc2n1)OCC>>CCOP(=O)(Cc1ccc2c(n1)CCCC2)OCC,O=[Pt]=O,O=C(O)C(F)(F)F,,,,test
US05817700,CI.CN(C)C(=O)Cc1ccsc1>>CC(C(=O)N(C)C)c1ccsc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20060047118A1,COc1cc(C(=O)OCc2ccccc2)ccc1Nc1ncc2nc(C)c(=O)n(C3CCCC3)c2n1>>COc1cc(C(=O)O)ccc1Nc1ncc2nc(C)c(=O)n(C3CCCC3)c2n1,,Cl,,,,test
US20020193599A1,CCOC(=O)CCCCCN=[N+]=[N-]>>[N-]=[N+]=NCCCCCC(=O)O,,CO,,O,[K+].[OH-],test
US20080132502A1,CC(=O)Nc1nc(C)c(-c2cnc(Cl)c(N)c2)s1.O=C=Nc1ccc(F)cc1F>>CC(=O)Nc1nc(C)c(-c2cnc(Cl)c(NC(=O)Nc3ccc(F)cc3F)c2)s1,,C1CCOC1,,,,test
US05891871,COC(=O)Cc1ccc2c(c1)OCO2.COc1cc(C(=O)O)ccc1[N+](=O)[O-]>>COC(=O)Cc1cc2c(cc1C(=O)c1ccc([N+](=O)[O-])c(OC)c1)OCO2,,ClCCCl,,O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3,,test
US20080312226A1,Nc1nncs1.O=C(Cl)OCC(Cl)(Cl)Cl>>O=C(Nc1nncs1)OCC(Cl)(Cl)Cl,,C1CCOC1,,O,c1ccncc1,test
US20070213331A1,CCN(CC)S(F)(F)F.COC(=O)[C@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C>>COC(=O)[C@H]1C[C@H](F)CN1C(=O)OC(C)(C)C,,ClCCl,,,,test
US20090048258A1,CCOc1ccc(C(=O)CCC(=O)O)cc1OCC.Nc1cc(-c2ccccc2)c2ccc(Br)cc2n1>>CCOc1ccc(C(=O)CCC(=O)Nc2cc(-c3ccccc3)c3ccc(Br)cc3n2)cc1OCC,,CC#N,CN(C)C=O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US06265575B1,COc1ccc(B(O)O)cc1.COc1ccc(Oc2c(I)sc3ccccc23)cc1>>COc1ccc(Oc2c(-c3ccc(OC)cc3)sc3ccccc23)cc1,,CCOC(C)=O,,,,test
US20120071512A1,Brc1cncc(Br)c1.CN1C(=O)Cc2c1ccc(B1OC(C)(C)C(C)(C)O1)c2Cl>>CN1C(=O)Cc2c1ccc(-c1cncc(Br)c1)c2Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,ClCCl,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20120245140A1,Cc1cc(C)c(S(=O)(=O)ON)c(C)c1.FC(F)(F)c1ccncc1>>Cc1cc(C)c(S(=O)(=O)[O-])c(C)c1.N[n+]1ccc(C(F)(F)F)cc1,,ClCCl,,,,test
US20090264442A1,CC(=O)NC1CCNC1.Cc1cc(OCCCl)nn1-c1ccc(Cl)c(Cl)c1>>CC(=O)NC1CCN(CCOc2cc(C)n(-c3ccc(Cl)c(Cl)c3)n2)C1,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20020161036A1,C#CCOc1ccc2c(C)cc(=O)oc2c1C(C)=O.O=Cc1ccc(F)cc1>>C#CCOc1ccc2c(C)cc(=O)oc2c1C(=O)C=Cc1ccc(F)cc1,,CCO,O,[K+].[OH-],,test
US20070254894A1,CN1CCC[C@H]1C(=O)Nc1cccc2cccnc12.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>CN1CCC[C@H]1C(=O)Nc1cccc2cccnc12.O=C(O)[C@H](O)[C@@H](O)C(=O)O,,CC(C)=O,,,,test
US20060142333A1,CN1CCCc2ccc([N+](=O)[O-])cc21>>CN1CCCc2ccc(N)cc21,[Pd],CO,,,,test
US20080146797A1,NCCN.S=C=Nc1ccccc1>>NCCNC(=S)Nc1ccccc1,,O,,C1CCOC1,Cl,test
US05374648,CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1/C=C/C(=O)Nc1ccccc1.C[Si](C)(C)CCOCCl>>CCOC(=O)c1c(/C=C/C(=O)Nc2ccccc2)c2c(Cl)cc(Cl)cc2n1COCC[Si](C)(C)C,,CN(C)C=O,O,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Nc1ccc(C2=NCCN2)cc1>>COc1ccc2nc(Nc3ccc(C4=NCCN4)cc3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US06197729B1,FC(=C1CCC2(CC1)OCCO2)C(F)F>>FC(F)C(F)C1CCC2(CC1)OCCO2,[Pd],CCO,,[H][H],,test
US05167858,CCC[C@@H]1CC[C@@H](CCc2c(Cl)nc(-c3ccc(F)c(F)c3)nc2Cl)CC1>>CCC[C@@H]1CC[C@@H](CCc2cnc(-c3ccc(F)c(F)c3)nc2)CC1,[Pd],CCO,,CCN(CC)CC,,test
US20130034494A1,C#CCOc1ccc(C=O)cc1.NCCCCCC(=O)O>>C#CCOc1ccc(CNCCCCCC(=O)O)cc1,,ClCCCl,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090099184A1,O=C(NCc1ccc(Cl)cc1Cl)c1ccc(F)nc1.Oc1ccccn1>>O=C(NCc1ccc(Cl)cc1Cl)c1ccc(Oc2ccccn2)nc1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20010010818A1,Nc1ccc(O[C@H]2O[C@H](CO)[C@H](O)[C@H](O[C@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@H]2O)cc1>>OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O,,CC#N,O,O=C([O-])O.[Na+],,test
US20150274777A1,COC(=O)CBr.c1ccc2c(c1)NCCO2>>COC(=O)CN1CCOc2ccccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070281933A1,CCS(=O)(=O)Cl.NC(=O)c1cc(-c2cccs2)cc2c(C3CCNCC3)n[nH]c12>>CCS(=O)(=O)N1CCC(c2n[nH]c3c(C(N)=O)cc(-c4cccs4)cc23)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US04937373,COC(=O)C(C)c1ccc2cc(OCCCCCCc3cccc(OCc4ccccc4)c3OCc3ccccc3)ccc2c1>>CC(C(=O)O)c1ccc2cc(OCCCCCCc3cccc(OCc4ccccc4)c3OCc3ccccc3)ccc2c1,,CO,,[Na+].[OH-],,test
US20070093523A1,CC(C)(C)[Si](C)(C)Cl.Cc1cccc(O)c1>>Cc1cccc(O[Si](C)(C)C(C)(C)C)c1,,ClCCl,,,,test
US20100152491A1,COc1ccc(CO)cc1OS(=O)(=O)c1ccc(C)cc1.O=S(Cl)Cl>>COc1ccc(CCl)cc1OS(=O)(=O)c1ccc(C)cc1,,c1ccccc1,,O=CO,,test
US20110098293A1,COCCOCCOCCN(Cc1ccc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)cc1)C(=O)OC(C)(C)C.Cc1cc(N)no1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COCCOCCOCCN(Cc1ccc(-c2cc3nccc(Oc4ccc(NC(=O)Nc5cc(C)on5)cc4F)c3s2)cc1)C(=O)OC(C)(C)C,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20090239810A1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.Sc1ccccc1Cl>>CC(C)(C)OC(=O)N1CCC(Sc2ccccc2Cl)CC1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20010046991A1,CN1CCN(c2ccc(N)cc2)CC1.Clc1c2ccccc2nc2ccccc12>>CN1CCN(c2ccc(Nc3c4ccccc4nc4ccccc34)cc2)CC1,Cl,CO,,,,test
US08618288B2,CC(C)(C)OC(=O)N1CCc2nc(Cc3ccccc3)nc(O)c2C1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCc2nc(Cc3ccccc3)nc(OS(=O)(=O)C(F)(F)F)c2C1,,C1CCOC1,O,CC(C)(C)[O-].[K+],,test
US20120101127A1,CC1(C)CC(c2cccc(N)c2)Nc2ccc(Cl)cc21.Cl.O=S=O>>CC1(C)CC(c2cccc(S(=O)(=O)Cl)c2)Nc2ccc(Cl)cc21,,CC(=O)O,O,O=N[O-].[Na+],,test
US20090124636A1,N[C@@H]1CCN(Cc2ccccc2)C1.O=Cc1ccccc1>>c1ccc(CN[C@@H]2CCN(Cc3ccccc3)C2)cc1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05026856,COc1cccc2c1CNC2.O=C(O)c1cn(-c2ccc(F)cc2)c2c(F)c(F)c(F)cc2c1=O>>COc1cccc2c1CN(c1c(F)cc3c(=O)c(C(=O)O)cn(-c4ccc(F)cc4)c3c1F)C2,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20120094972A1,CC1(C)CNc2cc(Br)cnc21.Cc1c(-c2ccccn2)nc2cc(F)ccc2c1Cl>>Cc1c(-c2ccccn2)nc2cc(F)ccc2c1N1CC(C)(C)c2ncc(Br)cc21,,CN1CCCC1=O,,C1COCCO1,Cl,test
US20150133424A1,COc1ccc(Cn2c(=O)c3c(Nc4ccc(I)cc4F)n(C)c(=O)c(C)c3n(-c3cccc(CCC(N)=O)c3)c2=O)cc1>>Cc1c(=O)n(C)c(Nc2ccc(I)cc2F)c2c(=O)[nH]c(=O)n(-c3cccc(CCC(N)=O)c3)c12,,COc1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20140249133A1,COc1cnc(-c2nn(Cc3ccccc3F)c3ccccc23)nc1N>>Nc1nc(-c2nn(Cc3ccccc3F)c3ccccc23)ncc1O,,CN1CCCC1=O,,,,test
US20110230493A1,CC(C)(C)OC(=O)N1CCC2(C=C(OS(=O)(=O)C(F)(F)F)CO2)CC1.OB(O)c1cccc(C(F)(F)F)c1>>CC(C)(C)OC(=O)N1CCC2(C=C(c3cccc(C(F)(F)F)c3)CO2)CC1,,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20140200344A1,CC[Mg]Br.C[Si](C)(C)CCOCn1ccc2c(Cl)c(C=O)cnc21>>CCC(O)c1cnc2c(ccn2COCC[Si](C)(C)C)c1Cl,,C1CCOC1,,[Cl-].[NH4+],,test
US06358971B1,O=C(c1ccccc1)c1ccc2nc(NC(=O)C(F)(F)F)c(-c3cc(F)ccc3F)n2c1>>Nc1nc2ccc(C(=O)c3ccccc3)cn2c1-c1cc(F)ccc1F,,CCOC(C)=O,,,,test
US20150148333A1,COC(=O)Cc1noc(C)c1-c1ccccc1NC(=O)OC(C)(C)C>>COC(=O)Cc1noc(C)c1-c1ccccc1N,,CO,Cl,,,test
US20100273764A1,Cc1nc(N)nc(-c2cc(F)cnc2Cl)n1.Nc1cncc(F)c1>>Cc1nc(N)nc(-c2cc(F)cnc2Nc2cncc(F)c2)n1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20150038510A1,Cc1cc2cn[nH]c2cc1-c1cc(F)cc2c(N)c(C(N)=O)nnc12.OC1CCNCC1>>Cc1cc2cn[nH]c2cc1-c1cc(N2CCC(O)CC2)cc2c(N)c(C(N)=O)nnc12,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,,test
US20100179126A1,CC(C)(C)[Si](C)(C)Cl.Cc1ncc(CCCO)cc1Nc1ncc2c(n1)-c1ccc(C(F)(F)F)cc1NC(=O)C2>>Cc1ncc(CCCO[Si](C)(C)C(C)(C)C)cc1Nc1ncc2c(n1)-c1ccc(C(F)(F)F)cc1NC(=O)C2,,C1CCOC1,,c1c[nH]cn1,,test
US20140142085A1,NC(=O)c1cc(-c2cccnc2[C@H](Cc2cc(F)cc(F)c2)NC(=O)Cn2nc(C(F)(F)F)c3c2CCC2(C3)OCCO2)ccc1F>>NC(=O)c1cc(-c2cccnc2[C@H](Cc2cc(F)cc(F)c2)NC(=O)Cn2nc(C(F)(F)F)c3c2CCC(=O)C3)ccc1F,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100144707A1,COCCOC(=O)c1cc(OCCOC)c(OC)cc1[N+](=O)[O-]>>COCCOc1cc(C(=O)O)c([N+](=O)[O-])cc1OC,,CCO,O,[Na+].[OH-],,test
US05580872,C1CCN(C2CCNCC2)CC1.CCOC(=O)c1cc(C2CC2)c2c(C)c(Cl)c(F)cn2c1=O>>Cc1c(N2CCC(N3CCCCC3)CC2)c(F)cn2c(=O)c(C(=O)O)cc(C3CC3)c12,,CC#N,,,,test
US04968809,N.O=S=O.[N-]=[N+]=C1c2ccccc2-c2ccc(Cl)cc21>>NS(=O)(=O)C1c2ccccc2-c2ccc(Cl)cc21,,C1CCOC1,,CCCCCC,,test
US20070259951A1,CS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)c([N+](=O)[O-])c2)cc1>>CS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)c(N)c2)cc1,[Zn],CC(=O)O,,,,test
US20040058903A1,CC(=O)c1ccc(-c2ccccc2C(=O)Nc2ccc(NC(=O)Cc3cccc(NC(=O)OC(C)(C)C)n3)cc2)cc1>>CC(=O)c1ccc(-c2ccccc2C(=O)Nc2ccc(NC(=O)Cc3cccc(N)n3)cc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20070021414A1,Cl.Oc1cc(F)c(C(O)CN2CCC(O)(c3cccc(F)c3)CC2)cc1F>>Cl.Oc1cc(F)c(C(O)CN2CCC(O)(c3cccc(F)c3)CC2)cc1F,,CCOC(C)=O,CO,,,test
US20140120087A1,BrC1CC1.Oc1cc(F)ccc1Br>>Fc1ccc(Br)c(OC2CC2)c1,,CCOC(C)=O,CN(C)C=O,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US20070241054A1,C=C(C)C(=O)OCCN.C=CC(=O)NC(C)C.NC(=O)C=CCC=CC(N)=O>>C=C(C)C(=O)OCCN.C=CC(=O)NC(C)C.NC(=O)C=CCC=CC(N)=O,,O,,,,test
US20110318388A1,CC1(C)[C@H]2CC[C@@H](CN)[C@@H]1C2.O=S(=O)(Cl)c1ccc(Br)cc1>>CC1(C)C2CCC(NS(=O)(=O)c3ccc(Br)cc3)C1C2,,ClCCl,,CCN(CC)CC,,test
US04205170,CC(C(N)=O)c1ccc2c(c1)C(=O)Cc1ccccc1O2.CCO>>CCOC(=O)C(C)c1ccc2c(c1)C(=O)Cc1ccccc1O2,O=S(=O)(O)O,,,,,test
US20030134854A1,CCCCO.COc1ccc(N2CCOCC2)c2sc(NC(=O)c3ccc(Cl)nc3)nc12>>CCCCOc1ccc(C(=O)Nc2nc3c(OC)ccc(N4CCOCC4)c3s2)cn1,,C1COCCO1,CN(C)C=O,[H-].[Na+],,test
US20120283238A1,C=O.FCCNC1CCC(Nc2ncnc3sc4c(c23)CCC4)CC1>>CN(CCF)C1CCC(Nc2ncnc3sc4c(c23)CCC4)CC1,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20040167123A1,CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(N)ccc3N2)c(O)c2cccnc21.CC(C)S(=O)(=O)Cl>>CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(NS(=O)(=O)C(C)C)ccc3N2)c(O)c2cccnc21,,c1ccncc1,,,,test
US20100267712A1,Brc1ccsc1.CC(C)=O.CCOC(CBr)OCC>>CCOC(CSc1cccc(Br)c1)OCC,,O,,O=C([O-])[O-].[K+].[K+],,test
US20160122339A1,CO.Cn1cc(-c2cnc3ccc(Br)cc3c2Cl)cn1>>COc1c(-c2cnn(C)c2)cnc2ccc(Br)cc12,,CO,,C[O-].[Na+],,test
US20090030015A1,COC(=O)c1cccc(NC(=O)c2cccc(-c3ccc(OC)cc3OC)c2)c1>>COc1ccc(-c2cccc(C(=O)Nc3cccc(C(=O)O)c3)c2)c(OC)c1,,CC#N,,,,test
US20100305093A1,CCOC(=O)c1cc(-c2ccccc2)cn1C>>Cn1cc(-c2ccccc2)cc1C(=O)O,,CO,,[Na+].[OH-],,test
US20050245589A1,CCOC(=O)C(C)(C)Oc1cc(Cl)c(OC(=O)c2ccccc2)cc1Cl>>COC(=O)C(C)(C)Oc1cc(Cl)c(O)cc1Cl,,CO,,Cl,[Na],test
US05017724,CN.Cc1ccc(O)c2c1C1CCCCC1C2=O>>CN=C1c2c(O)ccc(C)c2C2CCCCC12,,CO,,,,test
US20150376130A1,COC(=O)c1cccnc1Nc1cc(Cl)cc(OC)c1>>COc1cc(Cl)cc(Nc2ncccc2C(=O)O)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20140100210A1,OB(O)C1CC1.OCc1ccnc(Br)c1>>OCc1ccnc(C2CC2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,O,C1CCC(P(C2CCCCC2)C2CCCCC2)CC1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20070185096A1,C1CSCCN1.O=C(O)c1ccc(F)cc1F>>O=C(O)c1ccc(F)cc1N1CCSCC1,,CC#N,,CCN(CC)CC,,test
US04680287,NCc1ccccc1.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>OC[C@H]1O[C@@H](NCc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O,,CCO,,,,test
US20050137231A1,CB1OB(C)OB(C)O1.O=c1oc2c(I)c(O)ccc2c(Cc2ccc(OCCN3CCCC3)cc2)c1-c1ccc(Cl)cc1Cl>>Cc1c(O)ccc2c(Cc3ccc(OCCN4CCCC4)cc3)c(-c3ccc(Cl)cc3Cl)c(=O)oc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20120171199A1,O=Cc1nc2c(N3CCOCC3)nc(Cl)nc2n1C1CCCCO1>>OCc1nc2c(N3CCOCC3)nc(Cl)nc2n1C1CCCCO1,,CO,,[BH4-].[Na+],,test
US20150111857A1,Cc1nc(N2CCN(C(=O)OC(C)(C)C)CC2)ncc1Cc1ccccc1>>Cc1nc(N2CCNCC2)ncc1Cc1ccccc1,,C1COCCO1,,Cl,,test
US20080167303A1,CN(C(=O)OC(C)(C)C)C(CCN1c2ccccc2N(c2cccc(F)c2F)S1(=O)=O)c1ccccc1>>CNC(CCN1c2ccccc2N(c2cccc(F)c2F)S1(=O)=O)c1ccccc1,,CCOCC,,Cl,,test
US20120129870A1,CCC(CC)C(=O)Cl.CNc1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)c(F)c1>>CCC(CC)C(=O)Nc1ccc(N2CCNCC2)c(F)c1,,ClCCl,,O,,test
US20050119489A1,CI.Cc1nn(CCNC(=O)OC(C)(C)C)c(O)c1Sc1ccc(F)cc1>>COc1c(Sc2ccc(F)cc2)c(C)nn1CCNC(=O)OC(C)(C)C,,CCOC(C)=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US04377695,COC(=O)CCCCCCCn1c(=O)[nH]c2ccccc21.COc1ccc(CCl)cc1>>COC(=O)CCCCCCCn1c(=O)n(-c2ccc(OC)cc2)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US05151526,CC(O)c1cccc2ccccc12.O=S(Cl)Cl>>CC(Cl)c1cccc2ccccc12,,Cc1ccccc1,,,,test
US20120225858A1,C[C@@](N)(c1ccccc1F)[C@H]1COC[C@@H]1SCC#N>>C[C@]1(c2ccccc2F)N=C(N)CS[C@H]2COC[C@@H]21,,Cc1ccccc1,,C[Al](C)C,,test
US20160222007A1,CS(=O)(=O)OCC12CC1Oc1ccc(C(F)(F)F)cc12.N>>NCC12CC1Oc1ccc(C(F)(F)F)cc12,,CO,,,,test
US20060111422A1,COC(=O)CC(=O)CC(C=Cc1c(C(C)C)c(C(=O)N(C)Cc2ccccc2C)nn1-c1ccc(F)cc1)O[Si](C)(C)C(C)(C)C>>COC(=O)CC(=O)CC(O)C=Cc1c(C(C)C)c(C(=O)N(C)Cc2ccccc2C)nn1-c1ccc(F)cc1,,CC#N,O,CCOC(C)=O,,test
US20120196845A1,CN(C)/C=C1\C(=O)N(c2ccccc2F)N=C1c1ccccc1F.NCC1CCN(c2ccccc2)C(=O)C1>>O=C1CC(Cn2cc3c(=O)n(-c4ccccc4F)nc-3c3ccccc32)CCN1c1ccccc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US04983601,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C1Nc2cc(Br)ccc2N2CCc3cccc1c32>>S=C1Nc2cc(Br)ccc2N2CCc3cccc1c32,,Cc1ccccc1,,,,test
US20100034961A1,COc1cccc(O)c1C=O.O=[N+]([O-])O>>COc1ccc([N+](=O)[O-])c(O)c1C=O,,CC(=O)O,,,,test
US05559106,CCOP(=O)(CC(=O)NNc1nc2ccc(C(F)(F)F)cc2n(OCc2ccccc2)c1=O)OCC>>CCOP(=O)(CC(=O)NNc1nc2ccc(C(F)(F)F)cc2n(O)c1=O)OCC,[Pd],CCO,,,,test
US20090298744A1,BrP(Br)Br.OCC1CC1c1cccc(C(F)(F)F)c1>>FC(F)(F)c1cccc(C2CC2CBr)c1,,CCOCC,,,,test
US20130131164A1,NCc1ccc(F)cc1.Nc1cc(Cl)ccc1[N+](=O)[O-]>>Nc1cc(NCc2ccc(F)cc2)ccc1[N+](=O)[O-],II,CS(C)=O,,CCN(CC)CC,O,test
US20150051270A1,O=C(CBr)C1COc2ccccc2O1>>OC(CBr)C1COc2ccccc2O1,,CO,,[BH4-].[Na+],,test
US20090318475A1,COC(=O)CCCCCNc1ncnc2oc(-c3ccccc3)cc12.O=C1CCC(=O)N1Br>>COC(=O)CCCCCNc1ncnc2oc(-c3ccccc3)c(Br)c12,,ClC(Cl)(Cl)Cl,,,,test
US04281141,ClCc1c[nH]cn1.N#CC(c1ccccc1)c1ccc(Cl)cc1>>N#CC(Cc1c[nH]cn1)(c1ccccc1)c1ccc(Cl)cc1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20100331320A1,C=CC[C@]1(c2ccc(F)cc2)CCN([C@@H](C)c2ccc(-c3ccc(=O)[nH]c3)cc2)C(=O)O1.CI>>C=CC[C@]1(c2ccc(F)cc2)CCN([C@@H](C)c2ccc(-c3ccc(=O)n(C)c3)cc2)C(=O)O1,,C1CCOC1,,[H-].[Na+],,test
US04584293,CNC1CCc2c(cccc2OC)C1.COc1cc2c(cc1OC)CC(=O)N(CCCCl)CC2>>COc1cc2c(cc1OC)CC(=O)N(CCCN(C)C1CCc3c(cccc3OC)C1)CC2,,CCN(CC)CC,,,,test
US20120149684A1,C1CCNC1.CC(C)(C)OC(=O)N1CCC(c2nc(Br)cn2CCOS(C)(=O)=O)CC1>>CC(C)(C)OC(=O)N1CCC(c2nc(Br)cn2CCN2CCCC2)CC1,,CCOC(C)=O,,CN(C)C=O,,test
US20020156081A1,COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1NC(=O)OC(C)(C)C>>COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1N,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120329788A1,Fc1ccc(C2(C(F)(F)c3ccc(Oc4ncc(C(F)(F)F)cc4Cl)cn3)CO2)c(F)c1.c1nnn[nH]1>>OC(Cn1cnnn1)(c1ccc(F)cc1F)C(F)(F)c1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cn1,,CS(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US04873356,O=C(Cl)OCc1ccccc1.O=C(O)CP(=O)(O)CCCCc1ccccc1>>O=C(CP(=O)(O)CCCCc1ccccc1)OCc1ccccc1,,C1CCOC1,,CCN(CC)CC,,test
US20080317861A1,COC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C>>COC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)OC(C)(C)C,,CO,,O=C(O)C(F)(F)F,,test
US20080038242A1,CI.N#Cc1cccc(NCCCCOCc2ccccc2)c1>>CN(CCCCOCc1ccccc1)c1cccc(C#N)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20120196864A1,CCN1C(=N)/C(=C/c2ccc(OCc3ccc(C(F)(F)F)cc3C(F)(F)F)c(OC)c2)NC1=O.CON>>CCN1C(=O)NC(=C\c2ccc(OCc3ccc(C(F)(F)F)cc3C(F)(F)F)c(OC)c2)/C1=N\OC,,CO,,Cl,,test
US06492356B1,CC(C)(C)OC(=O)[C@H](CN)NC(=O)OCc1ccccc1.COC(=O)COc1ccc(C(=O)O)cc1>>COC(=O)COc1ccc(C(=O)NC[C@H](NC(=O)OCc2ccccc2)C(=O)OC(C)(C)C)cc1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20040014802A1,CCCC(=O)Cl.Nc1n[nH]c2cc(Br)ccc12>>CCCC(=O)Nc1n[nH]c2cc(Br)ccc12,,c1ccncc1,,,,test
US20080312226A1,CC(C)(C)OC(=O)N1CCCC(NC(=O)OCC(Cl)(Cl)Cl)C1.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>CC(C)(C)OC(=O)N1CCCC(NC(=O)N2CCN(c3nc(-c4ccccc4)ns3)CC2)C1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20070066624A1,BrCCCOCCCBr.Cc1nc(Oc2ccc(O)cc2)ccc1CN1CCC(N2C(=O)NC[C@H]2c2ccccc2)CC1>>COCCOc1ccc(Oc2ccc(CN3CCC(N4C(=O)NC[C@H]4c4ccccc4)CC3)c(C)n2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20120171245A1,COCC(O)CN1CCC[C@H](Nc2nc(-c3cn(S(=O)(=O)c4ccc(C)cc4)c4ncc(Cl)cc34)ncc2F)C1>>COCC(O)CN1CCC[C@H](Nc2nc(-c3c[nH]c4ncc(Cl)cc34)ncc2F)C1,,C1CCOC1,O,[Li+].[OH-],,test
US20120115900A1,C1CCNC1.Cc1cc(Cl)nc(Cl)c1[N+](=O)[O-]>>Cc1cc(Cl)nc(N2CCCC2)c1[N+](=O)[O-],,CC#N,,O,,test
US20040138449A1,CNC[C@@H](O)c1ccccn1.Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2sc(CCl)cc21>>CN(Cc1cc2c(s1)c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn2C)C[C@@H](O)c1ccccn1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,,test
US05138069,CC/C=C/c1nc(Cl)c(C=O)n1Cc1ccc(-c2ccccc2C(=O)OC)cc1>>CC/C=C/c1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2C(=O)OC)cc1,,CO,O,[Na+].[OH-],,test
US05973140,CCCCCCCCOc1c(Cl)c(Sc2ccccc2N)c(OCCCCCCCC)c(C#N)c1C#N.N>>CCCCCCCCOc1c(Cl)c(Sc2ccccc2N)c(OCCCCCCCC)c2c1C(=N)NC2=N,,CCCO,,[Na],,test
US20060135578A1,CC(=O)C(C)=NO.CCOC(=O)c1ccc(C=O)o1.Cl>>CCOC(=O)c1ccc(-c2nc(CCl)c(C)o2)o1,,CCOCC,,CCOC(C)=O,,test
US20030096847A1,COc1ccc2c(c1)CC(N)CC2.O=C(Cl)c1ccc(F)cc1>>COc1ccc2c(c1)CC(NC(=O)c1ccc(F)cc1)CC2,,CCOC(C)=O,ClCCl,O,c1ccncc1,test
US20140303153A1,CCI.O=C1c2c(c[nH]c(=O)c2N2CCOCC2)CN1CCc1ccc2ccccc2n1>>CCn1cc2c(c(N3CCOCC3)c1=O)C(=O)N(CCc1ccc3ccccc3n1)C2,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20070037790A1,Brc1nccs1.CCOC(=O)n1nc(NC(=O)c2ccc(F)cc2)c2c1CNC2>>O=C(Nc1[nH]nc2c1CN(c1nccs1)C2)c1ccc(F)cc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070232645A1,CCCOc1ccc(Sc2ccc(NC(C)=O)cc2)c(N)c1.Cc1ccc2c(Cl)ccnc2n1>>CCCOc1ccc(Sc2ccc(NC(C)=O)cc2)c(Nc2ccnc3nc(C)ccc23)c1,,CCO,,,,test
US20090192176A1,CC(C)(C)OC(=O)Nc1ccc(-c2nc(C3=CCOCC3)c3cnn(CC(F)(F)F)c3n2)cc1>>Nc1ccc(-c2nc(C3=CCOCC3)c3cnn(CC(F)(F)F)c3n2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090156608A1,Cc1cc(C)[nH]n1.Cc1nnc(Cl)c(Cl)c1-c1ccc(Cl)cc1>>Cc1cc(C)n(-c2c(Cl)nnc(C)c2-c2ccc(Cl)cc2)n1,,CCOC(C)=O,,C1CCOC1,[H-].[Na+],test
US20040132727A1,COc1cc2nccc(Oc3ccc(NC(=O)COc4cc(C)cc(C)c4)cc3)c2cc1OC>>COc1cc2nccc(Oc3ccc(NCCOc4cc(C)cc(C)c4)cc3)c2cc1OC,,C1CCOC1,,Cl,[Na+].[OH-],test
US20080182815A1,CC(=O)Cl.CSSc1ccc(N)cc1>>CSSc1ccc(NC(C)=O)cc1,,ClCCl,ClCCl,CCN(CC)CC,CCOC(C)=O,test
US20140371202A1,CN1CCC2(CC1)CC(C)(O)c1cc(Br)ccc1O2>>CC1=CC2(CCN(C)CC2)Oc2ccc(Br)cc21,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20150183799A1,CCC(C#N)c1ccc(-c2c(OC)ccc3[nH]c(=O)c4sccc4c23)cc1>>CCC(C#N)c1ccc(-c2c(O)ccc3[nH]c(=O)c4sccc4c23)cc1,,ClCCl,,BrB(Br)Br,,test
US20060100201A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1CCN(c2cc(N3CCNCC3)ccc2[N+](=O)[O-])CC1>>CC1CCN(c2cc(N3CCN(C(=O)OC(C)(C)C)CC3)ccc2[N+](=O)[O-])CC1,,C1CCOC1,ClCCl,,,test
US05688798,Cc1ncc(CCl)c(N)n1.c1ccc(COc2ccc3c(c2)CNCC3)cc1>>Cc1ncc(CN2CCc3ccc(OCc4ccccc4)cc3C2)c(N)n1,,CN(C)C=O,,CCN(CC)CC,,test
US04609736,CC(C)(C)C=O.O=C(O)CN1C(=O)CSC1=S>>CC(C)(C)C=C1SC(=S)N(CC(=O)O)C1=O,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US05308837,C=C(CCl)CCl.O=C1NC(=O)c2ccccc21>>C=C(CCl)CN1C(=O)c2ccccc2C1=O,,CN(C)C=O,,[K],,test
US20070249670A1,COC(=O)[C@@H](NC(=O)c1cc(-c2cccc(OC)c2)sc1NC(=O)Nc1c(Cl)cccc1Cl)C1CCCCC1>>COc1cccc(-c2cc(C(=O)N[C@H](C(=O)O)C3CCCCC3)c(NC(=O)Nc3c(Cl)cccc3Cl)s2)c1,,C1CCOC1,,[Li+].[OH-],,test
US20030220364A1,CI.Cc1cccc(CCO)c1Br>>COCCc1cccc(C)c1Br,,C1CCOC1,CC(=O)O,O,[H-].[Na+],test
US04514212,CN=C=O.NS(=O)(=O)c1ccccc1OCCCl>>CNC(=O)NS(=O)(=O)c1ccccc1OCCCl,,ClCCl,,CCN(CC)CC,,test
US20150239895A1,CC(=O)c1cn(CC(=O)O)c2ccc(N3CCN(C(C)=O)CC3)cc12.CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C.CN(C)C=O.F[P-](F)(F)(F)(F)F.O=C(Nc1cccc(Cl)n1)[C@@H]1NC[C@@H](F)C1Cl>>CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(-c3ccccc3Cl)c2F)c2ccc(N3CCN(C(C)=O)CC3)cc12,,CN(C)C=O,O,Cl,,test
US04017503,O=C(Cl)Cl.OCCOCc1ccccc1>>O=C(Cl)OCCOCc1ccccc1,,c1ccccc1,,,,test
US20100292263A1,CCOC(=O)CN(C(=O)C(C)(C)COCc1ccccc1)c1ccccc1>>CC(C)(COCc1ccccc1)C(=O)N(CC(=O)O)c1ccccc1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20130131135A1,CCOC(=O)C(C)Cc1cc(C)n(Cc2cc(Br)ccc2OCC2CCCC2)n1.CI>>CCOC(=O)C(C)(C)Cc1cc(C)n(Cc2cc(Br)ccc2OCC2CCCC2)n1,,C1CCOC1,,,,test
US20160083370A1,Cc1ccc(S(=O)(=O)OCCCCc2c[nH]c3ccc(C#N)cc23)cc1.Cc1nc(N2CCNCC2)sc1C#N>>Cc1nc(N2CCN(CCCCc3c[nH]c4ccc(C#N)cc34)CC2)sc1C#N,,CC#N,,[I-].[K+],,test
US05665737,CC(=O)Cl.COc1ccc(Cc2nc3c(O)cccc3o2)cc1OC1CCCC1>>COc1ccc(Cc2nc3c(OC(C)=O)cccc3o2)cc1OC1CCCC1,,CO,c1ccncc1,,,test
US20120004273A1,COC(=O)C1(NC(=O)Nc2ccc(C(F)(F)F)cc2)CCCCC1>>O=C1NC2(CCCCC2)C(=O)N1c1ccc(C(F)(F)F)cc1,,C1CCOC1,O,[Li]O,,test
US20100105782A1,CC1=CCC(COC(C)(C)CO)C1(C)C.CCO>>CC1=CCC(COC(C)(C)C(C)O)C1(C)C,[Pd],,,,,test
US20100048564A1,CC(C)(C)OC(=O)NCc1cc(Cl)ccc1[N+](=O)[O-].Oc1ccc(F)c(F)c1>>CC(C)(C)OC(=O)NCc1cc(Oc2ccc(F)c(F)c2)ccc1[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],,test
US20030105081A1,CCOC(=O)c1cccnc1C(OC)OC>>COC(OC)c1ncccc1CO,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140275027A1,CC(C)(C)OC(=O)N1CCC(c2cc3c(Cl)ccnc3[nH]2)C1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCC(c2cc3c(Cl)ccnc3n2C(=O)OC(C)(C)C)C1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20050096348A1,C[C@H]1COS(=O)(=O)N1C(=O)OC(C)(C)C.Oc1ccc2ccccc2c1>>C[C@@H](COc1ccc2ccccc2c1)NC(=O)OC(C)(C)C,,CN(C)C=O,,[Cl-].[NH4+],,test
US20100317822A1,O=C(O)c1ccc(C(=O)O)o1>>O=C(O)C1CCC(C(=O)O)O1,,CC(=O)O,,,,test
US20150366197A1,COc1cc(OCc2ccccc2)ccc1C(=O)c1c(-n2cccc2CO)ccn1S(=O)(=O)c1ccc(C)cc1>>COc1cc(OCc2ccccc2)ccc1C(=O)c1c(-n2cccc2C=O)ccn1S(=O)(=O)c1ccc(C)cc1,,CS(C)=O,,,,test
US04243682,CC(=O)Cl.COc1ccc2cccc(F)c2c1>>COc1ccc2cc(C(C)=O)cc(F)c2c1,,O=[N+]([O-])c1ccccc1,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20070037888A1,CC(C)(C)OC(=O)NCc1cc(C2CC2)no1>>NCc1cc(C2CC2)no1,,CO,,Cl,,test
US20110201643A1,O=C(NOC1CCCCO1)c1ccc2c(c1)CCNC2.O=C(O)C1CC1>>O=C(NOC1CCCCO1)c1ccc2c(c1)CCN(C(=O)C1CC1)C2,,CCN(CC)CC,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
US20130131035A1,O=C(O)C(F)(F)F.O=C([O-])N1CCc2c(cccc2OCC(F)(F)F)C1>>FC(F)(F)COc1cccc2c1CCNC2.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20150368238A1,CC(C)(C)[S@](=O)N1CCCC1c1cc(F)ccc1O[C@@H]1CCOC1.Cl>>Cl.Fc1ccc(O[C@@H]2CCOC2)c(C2CCCN2)c1,,C1COCCO1,,,,test
US03940394,CCOC(=O)CSc1nc(Cl)cc(Cl)n1.COc1ccc(N)cc1>>CCOC(=O)CSc1nc(Cl)cc(Nc2ccc(OC)cc2)n1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20160176869A1,NC(=O)c1cc(F)c(F)nc1Cl.O=CN1CCOCC1>>O=C1NC(O)c2c(F)c(F)nc(Cl)c21,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20150166535A1,CC#C[C@@H](CC(=O)OCC)c1ccc(OCc2ccc3nc(-c4c(C)cccc4C)nn3c2)cc1>>CC#C[C@@H](CC(=O)O)c1ccc(OCc2ccc3nc(-c4c(C)cccc4C)nn3c2)cc1,,CCO,,[Na+].[OH-],,test
US20110269738A1,CCc1c(CN2CC(C(=O)O)C2)cccc1-c1nnc(-c2ccc(OC(C)C)c(Cl)c2)s1.O=S(=O)(O)O>>CCc1c(C[NH+]2CC(C(=O)O)C2)cccc1-c1nnc(-c2ccc(OC(C)C)c(Cl)c2)s1.O=S(=O)([O-])O,,C1CCOC1,,,,test
US20080081818A1,O=C(NCc1ccc(OC(F)(F)F)cc1)[C@H]1CNCCN1S(=O)(=O)c1ccc(C(F)(F)F)cc1.O=c1[nH]ncc2sc(Cl)nc12>>O=C(NCc1ccc(OC(F)(F)F)cc1)[C@H]1CN(c2nc3c(=O)[nH]ncc3s2)CCN1S(=O)(=O)c1ccc(C(F)(F)F)cc1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US04568383,CCCC(=O)C1C(=O)CC(C2=C(C)CCCC2(C)C)C(C(=O)OC)C1=O.CCON>>CCCC(NOCC)=C1C(=O)CC(C2=C(C)CCCC2(C)C)C(C(=O)OC)C1=O,,CCO,,,,test
US20100286145A1,COC(=O)c1cc(N)cc(C(=O)OC)c1.CS(=O)(=O)Cl>>COC(=O)c1cc(NS(C)(=O)=O)cc(C(=O)OC)c1,,ClCCl,,c1ccncc1,,test
US20060089370A1,CC(=O)COc1ccc(CCNC(=O)OC(C)(C)C)cc1>>CC(=O)COc1ccc(CCN)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150329506A1,C/C(=N\[S@](=O)C(C)(C)C)c1ccc(F)cc1F.CC(=O)c1cncnc1>>CC(C)(C)[S@@](=O)N[C@@](C)(CC(=O)c1cncnc1)c1ccc(F)cc1F,,CN(C)C=O,,[H-].[Na+],,test
US20070197581A1,Fc1ccc(F)c2c1OCC1OC21.Sc1ccc(Cl)cc1>>OC1COc2c(F)ccc(F)c2C1Sc1ccc(Cl)cc1,,ClCCl,,O,,test
US06093838,CC(C)I.COc1ccc(Nc2cc3c(c(C(C)C)c2C)OCC3(C)C)cc1>>COc1ccc(N(c2cc3c(c(C(C)C)c2C)OCC3(C)C)C(C)C)cc1,,C1CCOC1,,[Li]CCCC,,test
US20110152316A1,CC(=O)O.COC(=O)c1cc(CCN)cc2ccccc12>>COC(=O)c1cc(CCNC(C)=O)cc2ccccc12,,CCOCC,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04123538,NC12CC3CC(CC(C3)C1)C2.O=C1COCC(=O)O1>>O=C(O)COCC(=O)NC12CC3CC(CC(C3)C1)C2,,ClCCl,,,,test
US04786310,CCN1CCCCC1C(=O)O.CCn1c(=O)sc2cc(F)c(N=C=O)cc21>>CCn1c(=O)sc2cc(F)c(N3C(=O)C4CCCCN4C3=O)cc21,,Cc1ccccc1,,CCN(CC)CC,O,test
US20130253204A1,CC[Mg]Br.N#CCc1ccccc1>>NC1(Cc2ccccc2)CC1,,C1CCOC1,,[Na+].[OH-],,test
US20130053341A1,CN(C)CC#Cc1ccc2nc(Cl)nc(Nc3ccc(F)c(Cl)c3)c2c1.OB(O)c1cccnc1>>CN(C)CC#Cc1ccc2nc(-c3cccnc3)nc(Nc3ccc(F)c(Cl)c3)c2c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US04314942,C=CCOC(=O)Cl.NC12CC3CC(CC(C3)C1)C2>>C=CCOC(=O)NC12CC3CC(CC(C3)C1)C2,,ClCCl,,CCN(CC)CC,,test
US20120178715A1,CC(C)[C@H]1CN(CCO)C(=O)N1c1ccn2ncc(-c3ccc(-c4ncn(COCC[Si](C)(C)C)n4)cc3)c2n1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCCN2C[C@H](C(C)C)N(c3ccn4ncc(-c5ccc(-c6ncn(COCC[Si](C)(C)C)n6)cc5)c4n3)C2=O)cc1,,c1ccncc1,,,,test
US20010031874A1,CN(C)c1cccc2c(S(=O)(=O)Cl)cccc12.COc1ccc(C(=O)Nc2ccccc2)cc1N>>COc1ccc(C(=O)Nc2ccccc2)cc1NS(=O)(=O)c1cccc2c(N(C)C)cccc12,,O,,c1ccncc1,,test
US20150336934A1,Cc1cnc(-c2ccc(-c3ccc(N)cc3F)c3c2C(=O)NC3)[nH]1.O=C(O)c1ccc(F)cc1F.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>Cc1cnc(-c2ccc(-c3ccc(NC(=O)Nc4ccc(F)cc4F)cc3F)c3c2C(=O)NC3)[nH]1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US04874775,CS(=O)(=O)Cl.Clc1ccc(NCc2ccncc2)cc1>>CS(=O)(=O)N(Cc1ccncc1)c1ccc(Cl)cc1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US04267176,COC(=O)Cc1ccnc(N)n1.O=CO>>COC(=O)Cc1ccnc(NC=O)n1,,CCOC(C)=O,,CC(=O)OC(C)=O,,test
US20150284401A1,C1CCOC1.C1CCOC1.O=C(CCl)N[C@@H](c1ccc2ccccc2c1)[C@@H](NC(=O)CCl)c1ccc2ccccc2c1>>c1ccc2cc([C@H]3[C@H](c4ccc5ccccc5c4)N4CCN3CC4)ccc2c1,,C1CCOC1,,B,,test
US20160016903A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCCCC1(N(C)C)CCC2(CC1)CNC(=O)C2>>CCCCC1(N(C)C)CCC2(CC1)CC(=O)N(C(=O)OC(C)(C)C)C2,CN(C)c1ccncc1,C1CCOC1,CC#N,,,test
US20080009482A1,CC(C)N1CCC(=O)N(C)c2cnc(Cl)nc21.Nc1ccc(C(=O)NCCN2CCOCC2)cc1>>CC(C)N1CCC(=O)N(C)c2cnc(Nc3ccc(C(=O)NCCN4CCOCC4)cc3)nc21,,CO,O,CCO,Cl,test
US20020133021A1,CC(C)(C)OC(=O)NC[C@H]1CN(c2ccc3c(c2)CCNC3)C(=O)O1.O=C(Cl)COCc1ccccc1>>CC(C)(C)OC(=O)NC[C@H]1CN(c2ccc3c(c2)CCN(C(=O)COCc2ccccc2)C3)C(=O)O1,,ClCCl,,CCN(CC)CC,,test
US20040266758A1,C=CCC1Oc2cccc(OC)c2-c2ccc3c(c21)NC(=O)C(C)(C)N3.CI>>C=CCC1Oc2cccc(OC)c2-c2ccc3c(c21)N(C)C(=O)C(C)(C)N3,,CC#N,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US07015218B1,CCOC(=O)c1cnn(-c2ccc(F)cc2)c1>>O=C(O)c1cnn(-c2ccc(F)cc2)c1,,CCO,O,[Na+].[OH-],,test
US20070254873A1,Cc1ccc(O)cc1.NC(=O)c1cc(-c2ccccc2)cc2c(C3CCN(S(=O)(=O)CCCCl)CC3)c[nH]c12>>Cc1ccc(OCCCS(=O)(=O)N2CCC(c3c[nH]c4c(C(N)=O)cc(-c5ccccc5)cc34)CC2)cc1,,CS(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20040082563A1,O=[N+]([O-])c1ccc(F)cc1.Oc1ccccn1>>O=c1ccccn1-c1ccc([N+](=O)[O-])cc1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US05726191,C#CCCCC.CC1(C)CCCCc2ccc(Br)cc21>>CCCCC#Cc1ccc2c(c1)C(C)(C)CCCC2,,C1CCNCC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070185144A1,CI.COc1cc(C[C@H]2[C@@H](CO)OC(C)(C)N2C(=O)OC(C)(C)C)ccn1>>Cn1ccc(C[C@H]2[C@@H](CO)OC(C)(C)N2C(=O)OC(C)(C)C)cc1=O,,CO,,,,test
US20140094465A1,COCCl.Oc1ccc2cc(Br)c(O)cc2c1>>COCOc1cc2cc(O)ccc2cc1Br,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040053941A1,CCI.CCc1nc(N[C@@H](CC)CO)c(CC)nc1Br>>CCOC[C@H](CC)Nc1nc(CC)c(Br)nc1CC,,CN(C)C=O,,[H-].[Na+],,test
US20080207598A1,C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1.NC(=O)CBr>>C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1CC(N)=O,,CC#N,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20140315888A1,C=O.Clc1cnc2nc(N3CC4CCCNC4C3)c3nncn3c2c1>>CN1CCCC2CN(c3nc4ncc(Cl)cc4n4cnnc34)CC21,,CCOC(C)=O,CO,[BH4-].[Na+],,test
US20090099224A1,CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2CC[Si](C)(C)CCCO[Si](CC)(CC)CC.O=C(Cl)Cl.OCc1ccccc1>>CCC1(OC(=O)OCc2ccccc2)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2CC[Si](C)(C)CCCO[Si](CC)(CC)CC,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20150246912A1,CC(C)(CO[Si](C)(C)C(C)(C)C)n1cc(C(=O)c2cncc(N)c2)c2cncc(F)c21.Cc1cc(C(F)(F)F)nn1CC(=O)O>>Cc1cc(C(F)(F)F)nn1CC(=O)Nc1cncc(C(=O)c2cn(C(C)(C)CO[Si](C)(C)C(C)(C)C)c3c(F)cncc23)c1,,C1CCOC1,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US04108993,C=O.O=C1NOCCN1c1ccc(Cl)c(Cl)c1>>O=C1N(CO)OCCN1c1ccc(Cl)c(Cl)c1,,C1COCCO1,,CC(=O)[O-].[Na+],,test
US06380239B1,CCOC(=O)N1C(=O)c2cccc([N+](=O)[O-])c2C1=O.N[C@@H](CCC(=O)O)C(=O)O>>O=C(O)CCC(C(=O)O)N1C(=O)c2cccc([N+](=O)[O-])c2C1=O,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20080207609A1,CC(C)(C)[Si](C)(C)Cl.Oc1cccc(-c2nc(N3CCOCC3)c3sccc3n2)c1>>CC(C)(C)[Si](C)(C)Oc1cccc(-c2nc(N3CCOCC3)c3sccc3n2)c1,,CN(C)C=O,,c1c[nH]cn1,,test
US04382949,C=CCOC(=O)N[C@H](CSSC[C@@H](N)C(=O)OCC=C)C(=O)OCC=C>>C=CCOC(=O)N[C@H](CS)C(=O)OCC=C,[Zn],CO,,Cl,,test
US20110230458A1,CCOC(=O)C=O.O=C(Cc1ccc(OC2CCCCC2)cc1)C1CCC1>>CCOC(=O)C(O)C(C(=O)C1CCC1)c1ccc(OC2CCCCC2)cc1,,C1CCOC1,,CCN(CC)CC,,test
US04720586,COc1ccc(CCN)cc1OC.O=C(O)CCCCCCCCc1ccccc1>>COc1ccc(CCNC(=O)CCCCCCCCc2ccccc2)cc1OC,,ClCCl,,O,,test
US05312924,CC(C)CC(N)c1ccccc1N1CCCCC1>>CC(C)C[C@H](N)c1ccccc1N1CCCCC1,,CC(C)=O,,CO,,test
US05290780,C[Sn](C)(C)N=[N+]=[N-].N#Cc1ccccc1Br>>C[Sn](C)(C)n1nnnc1-c1ccccc1Br,,Cc1ccccc1,,,,test
US20120264737A1,CCc1cc(C)c(N)cc1C(=O)O.N#Cc1ccc(C2(F)CCNCC2)cc1>>CCc1cc(C)c(N)cc1C(=O)N1CCC(F)(c2ccc(C#N)cc2)CC1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160000760A1,Nc1nc(Nc2ccc(Br)c(Cl)c2)n[nH]1.OB(O)c1ccc(F)c(F)c1>>Nc1nc(Nc2ccc(-c3ccc(F)c(F)c3)c(Cl)c2)n[nH]1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20060135578A1,CCOP(=O)(/C=C/c1cn(-c2ccccc2)nc1OCc1ccccc1)OCC>>CCOP(=O)(CCc1cn(-c2ccccc2)nc1O)OCC,[Pd],C1CCOC1,,,,test
US20130157996A1,COC(=O)C(=O)N(C)c1cc(C(=O)N[C@@H](c2ccc(OC(F)(F)F)c(F)c2)c2ncccc2F)ccc1[N+](=O)[O-]>>Cn1c(=O)c(=O)n(O)c2ccc(C(=O)N[C@@H](c3ccc(OC(F)(F)F)c(F)c3)c3ncccc3F)cc21,,CO,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20150329538A1,C1COCCN1.O=C(O)c1ccc2cccc(Br)c2n1>>O=C(c1ccc2cccc(Br)c2n1)N1CCOCC1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20160046596A1,COc1cc(C=Nc2ccc(F)c(Cl)c2)c(O)cn1.C[Si](C)(C)C#N>>COc1cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc2cn1,,ClCCl,,,,test
US04311699,Nc1ccc(-c2ncc(C(=O)O)c(O)n2)cc1.O=C1CCC(C(=O)O)N1>>O=C1CCC(C(=O)Nc2ccc(-c3ncc(C(=O)O)c(O)n3)cc2)N1,,CN(C)C=O,ClCCl,CCN(CC)CC,O=S(Cl)Cl,test
US20060235021A1,Cn1cc(CO)c(C(F)(F)F)n1.Oc1cc(-c2cnnc(-c3ccccc3)c2)ccc1F>>Cn1cc(COc2cc(-c3cnnc(-c4ccccc4)c3)ccc2F)c(C(F)(F)F)n1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04198406,CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](N)[C@H]2SC1.NC(=O)Cn1nnnc1S>>NC(=O)Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(N)[C@H]2SC1,,CC(C)=O,,O=C([O-])O.[Na+],,test
US20110263588A1,CCOC(=O)C(=O)OCC.CNN.O=C1CCCc2cccnc21>>CCOC(=O)c1nn(C)c2c1CCc1cccnc1-2,,CCO,,C,C[O-].[Na+],test
US20100286148A1,O=C(OCCl)c1cccc(F)c1.O=c1nc(-c2cc(C(F)(F)F)ccn2)[nH]o1>>O=C(OCn1c(-c2cc(C(F)(F)F)ccn2)noc1=O)c1cccc(F)c1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20080161254A1,CC(=O)OC(C(=O)NC1CC1)[C@H](CC1CCC1)NC(=O)OCC1c2ccccc2-c2ccccc21>>O=C(N[C@@H](CC1CCC1)C(O)C(=O)NC1CC1)OCC1c2ccccc2-c2ccccc21,,CO,,O,O=S(=O)(O)O,test
US20070254937A1,Brc1csc(COCc2ccccc2)c1.O=CN1CCCCC1>>O=Cc1sc(COCc2ccccc2)cc1Br,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20160102071A1,CC#C[C@@H](CC(=O)OCC)c1ccc(O)cc1.ClCc1ccc2scc(Br)c2c1>>CC#C[C@@H](CC(=O)OCC)c1ccc(OCc2ccc3scc(Br)c3c2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130261086A1,COc1c([N+](=O)[O-])ccc(C=O)c1Cl>>COc1c([N+](=O)[O-])ccc(CO)c1Cl,,CO,,O,[BH4-].[Na+],test
US20090267491A1,BrCc1cccc2ccccc12.C1=C(N2CCCC2)CCc2ccccc21.CCOC(C)=O>>O=C1CCc2ccccc2C1Cc1cccc2ccccc12,,CCCCCC,CCOC(C)=O,C1COCCO1,Cl,test
US20080188528A1,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2.O=C(O)c1ccc(=O)n(C(c2ccccc2)c2ccccc2)c1>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)c2ccc(=O)n(C(c3ccccc3)c3ccccc3)c2)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060116406A1,CC(C)[N-]C(C)C.CCOC(=O)C(F)(F)F.Sc1nccs1.[Li+]>>CC(C)[N-]C(C)C.O=C(c1cnc(S)s1)C(F)(F)F.[Li+],,C1CCOC1,,,,test
US20140315917A1,CC1(C)CC(N2CCN(C(=O)Cl)C2=O)CCO1.Cn1cc(-c2cc(Oc3ccc(N)nc3)ccn2)cn1>>Cn1cc(-c2cc(Oc3ccc(NC(=O)N4CCN(C5CCOC(C)(C)C5)C4=O)nc3)ccn2)cn1,,ClCCl,,,,test
US05932569,CN(C)C=O.c1ccc(CCn2cncn2)cc1>>O=Cc1ncnn1CCc1ccccc1,,C1CCOC1,CCCCCC,CC(C)NC(C)C,[Li]CCCC,test
US20090005353A1,CS(=O)(=O)Oc1ccccc1O.Cc1ccc(S(=O)(=O)OCCNC2=C(c3ccccc3)S(=O)(=O)N(C(C)C)C2=O)cc1>>CC(C)N1C(=O)C(NCCOc2ccccc2OS(C)(=O)=O)=C(c2ccccc2)S1(=O)=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US06391916B1,C#CCCCCC#C/C(=C\c1ccccc1)CO.II>>OC/C(C#CCCCCC#CI)=C/c1ccccc1,,Cc1ccccc1,,C1COCCN1,,test
US20150183790A1,C#CCCCCOC1CCCCO1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)C#CCCCCOC1CCCCO1,,C1CCOC1,,[Li]CCCC,,test
US20110053921A1,COC(=O)C(C)(C)OC1CCCCO1>>CC(C)(CO)OC1CCCCO1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06100272,COC(=O)c1ccc(-c2ccc(NC(=O)NCCCl)cc2C)cc1>>COC(=O)c1ccc(-c2ccc(N3CCNC3=O)cc2C)cc1,,O,,,,test
US20120252777A1,C[C@H]1CCCN1c1cccc(Nc2nc(-c3cccc(CNC4CCN(C(=O)OC(C)(C)C)CC4)c3)nc3scnc23)c1.O=C(O)C(F)(F)F>>C[C@H]1CCCN1c1cccc(Nc2nc(-c3cccc(CNC4CCNCC4)c3)nc3scnc23)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20100056524A1,O=[N+]([O-])c1ccc(-c2cnco2)nc1>>Nc1ccc(-c2cnco2)nc1,[Pd],CCO,,,,test
US20160108046A1,CC(C)(C)OC(=O)NC1CCNCC1.Clc1cncc(Cl)n1>>CC(C)(C)OC(=O)NC1CCN(c2cncc(Cl)n2)CC1,,CN1CCCC1=O,,CCN(CC)CC,,test
US20060270726A1,ClCCC(Cl)(Cl)Cl.OCCOc1c(Cl)cc(O)cc1Cl>>OCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05059590,C#Cc1c(C#N)ncn1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O.OO>>C#Cc1c(C(N)=O)ncn1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O,,CO,N,,,test
US05455348,CC(C)(CCCl)C(=O)[O-].N=C(NC(=O)OCc1ccccc1)c1ccc(-c2ccc(OC[C@@H]3C[C@@H](CC(=O)O)C(=O)N3)cc2)nc1>>CC(C)(C)C(=O)OCOC(=O)C[C@@H]1C[C@@H](COc2ccc(-c3ccc(C(=N)NC(=O)OCc4ccccc4)cn3)cc2)NC1=O,,CS(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20150087639A1,CC(=O)C=C=O.Nc1ccc(N2CCOCC2=O)c(F)c1>>CC(=O)CC(=O)Nc1ccc(N2CCOCC2=O)c(F)c1,,CCOC(C)=O,,,,test
US20060089394A1,CCOC(=O)COc1ccc(O)cc1C.CCOCC(O)c1cccc(Br)n1>>CCOCC(Oc1ccc(OCC(=O)OCC)c(C)c1)c1cccc(Br)n1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050143421A1,CC(=O)NC[C@H]1CN(c2ccc(N3CCC4(CC3)OCCO4)c(F)c2)C(=O)O1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(=S)NC[C@H]1CN(c2ccc(N3CCC4(CC3)OCCO4)c(F)c2)C(=O)O1,,C1COCCO1,,,,test
US05399574,CN1CC=C(c2c[nH]c3ccc(C=C4NC(=O)NC4=O)cc23)CC1>>CN1CCC(c2c[nH]c3ccc(CC4NC(=O)NC4=O)cc23)CC1,[Pd],CCO,O,[H][H],,test
US20100029782A1,CCOC(=O)CC(CC)c1cc(F)c(F)c([C@H](O)CO)c1.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOC(=O)CCc1cc(F)c(F)c([C@H](O)COS(=O)(=O)c2ccc(C)cc2)c1,,c1ccncc1,,,,test
US20080090805A1,O=C(O)c1ccc(Sc2ccc(F)cc2C(=O)O)c([N+](=O)[O-])c1>>Nc1cc(C(=O)O)ccc1Sc1ccc(F)cc1C(=O)O,,CCO,,O,,test
US20150152047A1,COC(=O)c1ccc(NC2CCN(C(=O)OC(C)(C)C)CC2)c(OC)c1>>COc1cc(C(=O)O)ccc1NC1CCN(C(=O)OC(C)(C)C)CC1,,CO,,,,test
US20120258968A1,COc1ccccc1B(O)O.Clc1cc(Nc2cccc(CNc3nc4ccccc4[nH]3)c2)ncn1>>COc1ccccc1-c1cc(Nc2cccc(CNc3nc4ccccc4[nH]3)c2)ncn1,,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US20130079335A1,C1CCNC1.CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(-c3ccc(C=O)cc3)ccc2-n2c(C)nnc21>>CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(-c3ccc(CN4CCCC4)cc3)ccc2-n2c(C)nnc21,,CC(=O)O,ClCCl,O=C([O-])O.[Na+],,test
US04350695,NN.O=[N+]([O-])c1ccc2nc(Cl)nc(O)c2c1>>NNc1nc(O)c2cc([N+](=O)[O-])ccc2n1,,O,,,,test
US20140336190A1,CCN(CC)S(F)(F)F.Cc1noc(C)c1-c1cc(C(O)(c2cccnc2)c2ncco2)c2nc(C3CC3)[nH]c2c1>>Cc1noc(C)c1-c1cc(C(F)(c2cccnc2)c2ncco2)c2nc(C3CC3)[nH]c2c1,,ClCCl,,CCOC(C)=O,,test
US06143764,COc1cc2nccc(C(C#N)c3ccc(Br)cc3)c2cc1OC>>COc1cc2nccc(Cc3ccc(Br)cc3)c2cc1OC,,O=S(=O)(O)O,,Cl,N,test
US20150094297A1,COc1nn2cc(-c3cc4c(OCc5csc(-c6ccc(C(=O)OC(C)(C)C)cc6)n5)cc(F)cc4o3)nc2s1>>COc1nn2cc(-c3cc4c(OCc5csc(-c6ccc(C(=O)O)cc6)n5)cc(F)cc4o3)nc2s1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130035446A1,O=C(/C=C/c1ccc(C(F)(F)Oc2ccc(OCCCC(F)(F)F)cc2)cc1)OCCCCCCOC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>Nc1cc(N)cc(C(=O)OCCCCCCOC(=O)/C=C/c2ccc(C(F)(F)Oc3ccc(OCCCC(F)(F)F)cc3)cc2)c1,[Zn],CN(C)C=O,O,,,test
US20020002268A1,COC(=O)C(NC(=O)OC(C)(C)C)c1ccccc1>>COC(=O)C(NC(=O)OC(C)(C)C)C1CCCCC1,[Rh],CO,,CC(=O)O,[H][H],test
US20110039843A1,O=[N+]([O-])O.Oc1ccc(C(F)(C(F)(F)F)C(F)(F)F)cc1>>O=[N+]([O-])c1cc(C(F)(C(F)(F)F)C(F)(F)F)ccc1O,,O,,CC(=O)O,O=S(=O)(O)O,test
US20080287474A1,COc1ccccc1B(O)O.Clc1cc(Cl)ncn1>>COc1ccccc1-c1cc(Cl)ncn1,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20090131458A1,CO.Nc1nc(OCC2CCCO2)nc2c1nc(Br)n2C1CCCCO1>>COc1nc2c(N)nc(OCC3CCCO3)nc2n1C1CCCCO1,,CO,,C[O-].[Na+],,test
US20110312936A1,C=CC[Mg]Br.CCOC(=O)C1CCC2(CC1)OCCO2>>C=CCC(O)C1CCC2(CC1)OCCO2,,C1CCOC1,,,,test
US20030130277A1,Cc1ccc2c(c1)c(=O)c1c(cnn1C)n2C1CCN(C(=O)OC(C)(C)C)CC1>>Cc1ccc2c(c1)c(=O)c1c(cnn1C)n2C1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160009744A1,Cc1cc(Cc2cccc(Cl)c2)sc1C(O)c1cncnc1Cl>>Cc1cc(Cc2cccc(Cl)c2)sc1C(=O)c1cncnc1Cl,O=[Mn]=O,ClCCl,,,,test
US04742060,N=C(N)N[N+](=O)[O-].NCCCNCc1ccc(Cl)nc1>>O=[N+]([O-])N=C1NCCCN1Cc1ccc(Cl)nc1,,O,,,,test
US20100217012A1,N#CCOc1ccc(Cl)cc1.O=[N+]([O-])c1ccc2c(c1)O[C@@H](CNCc1ccccc1)CO2>>N#CCc1c([N+](=O)[O-])ccc2c1O[C@@H](CNCc1ccccc1)CO2,,CN(C)C=O,,Cl,CC(C)(C)[O-].[K+],test
US20130096160A1,CC(C)(C)OC(=O)NC1CCN(c2nc(-c3ccc(Br)cc3)cs2)CC1>>NC1CCN(c2nc(-c3ccc(Br)cc3)cs2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05866724,C=O.CC(=O)O.Cc1cc(C(C)(c2ccccc2)c2ccc(O)c(C)c2)ccc1O.O>>Cc1cc(C(C)(c2ccccc2)c2cc(C)c(O)c(CO)c2)cc(CO)c1O,,CC(=O)O,Cc1ccccc1,CCOC(C)=O,[Na+].[OH-],test
US20100081641A1,CN(Cc1cnc(F)cc1-c1cccc2cc(-c3nc(NCCn4cc[nH]c4=O)ncc3F)sc12)C(=O)OC(C)(C)C>>CNCc1cnc(F)cc1-c1cccc2cc(-c3nc(NCCn4cc[nH]c4=O)ncc3F)sc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130102584A1,COC(=O)c1ccc(Nc2ccc(F)cc2)c(N)c1.O=C(n1ccnc1)n1ccnc1>>COC(=O)c1ccc2c(c1)[nH]c(=O)n2-c1ccc(F)cc1,,CN(C)C=O,,,,test
US20030069238A1,C1CCNCC1.CC(=O)N1CCN(C(=O)c2cccc(Sc3cnc(Nc4cccc(Br)n4)s3)c2)CC1>>CC(=O)N1CCN(C(=O)c2cccc(Sc3cnc(Nc4cccc(N5CCCCC5)n4)s3)c2)CC1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20070167436A1,CC(C)N1CCN(C(=O)[C@@H]2CC[C@@H](N)CC2)CC1.N#Cc1ccc(Cl)nc1>>CC(C)N1CCN(C(=O)[C@@H]2CC[C@@H](Nc3ccc(C#N)cn3)CC2)CC1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20050176791A1,Nc1ncc(-c2c(OCc3ccccc3)ccc3ccccc23)o1>>Nc1ncc(-c2c(O)ccc3ccccc23)o1,[Pd],CCO,,[H][H],,test
US20080280933A1,CCN(CC)S(F)(F)F.Cc1nc2ccccc2n1CO>>Cc1nc2ccccc2n1CF,,ClCCl,,[Na+].[OH-],,test
US07105680B1,COCOc1ccc(OC)cc1C=Nc1c(C)cccc1O>>COCOc1ccc(OC)cc1-c1nc2c(C)cccc2o1,,c1ccccc1,,,,test
US20130156756A1,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.O=C(O)Cc1ccc(F)cc1>>O=C(Cc1ccc(F)cc1)Nc1ccc(B(O)O)cn1,,CN(C)C=O,ClCCl,Cl,O=C(Cl)C(=O)Cl,test
US20050288273A1,NC[C@H]1CN(c2ccc3c(c2)CCCc2cn[nH]c2-3)C(=O)O1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C1O[C@@H](CNC(=O)C(F)(F)F)CN1c1ccc2c(c1)CCCc1cn[nH]c1-2,,ClCCl,,Cl,,test
US20130116235A1,COC(=O)c1cc2n(c1/C=N/S(=O)C(C)(C)C)CCCC2>>COC(=O)c1cc2n(c1CNS(=O)C(C)(C)C)CCCC2,,O,,CO,[BH4-].[Na+],test
US20080176862A1,CC1(C)OB(c2cc(C#N)cc(OS(C)(=O)=O)c2)OC1(C)C.CN1C(=O)C(c2ccc(OC(F)F)cc2)(c2ccc(F)c(Br)c2)N=C1N.Cl>>CN1C(=O)C(c2ccc(OC(F)F)cc2)(c2ccc(F)c(-c3cc(C#N)cc(OS(C)(=O)=O)c3)c2)N=C1N.Cl,,CCOCC,ClCCl,,,test
US20080015180A1,C1=C(c2ccccc2)CCNC1.O=S1(=O)CCCO1>>O=S(=O)(O)CCCN1CC=C(c2ccccc2)CC1,,CC(C)=O,,,,test
US20140086834A1,COc1cccc(C(=O)CBr)c1.c1ccc(-c2cccnc2N2CCNCC2)nc1>>COc1cccc(C(=O)CN2CCN(c3ncccc3-c3ccccn3)CC2)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150225342A1,COC(=O)c1ccc(N=C=O)cc1.ClCCl.OC1(c2ccccc2)CC2CNCC2C1>>COC(=O)c1ccc(NC(=O)N2CC3CC(O)(c4ccccc4C)CC3C2)cc1,,ClCCl,O,CCN(CC)CC,,test
US20100113444A1,NC1CCCN(C(=O)OCc2ccccc2)C1.O=C(Cl)CC(=O)Cl.O=C(OCc1ccccc1)N1CCCC(N2C(=O)CC(=O)N(C3CCCCC3)C2=O)C1.O=C=NC1CCCCC1>>O=C(O)CNC(=O)c1c(O)n(C2CCCNC2)c(=O)n(C2CCCCC2)c1=O,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20020151535A1,CC(C)(C)OC(=O)C[C@@H](CCCC1CCCCC1)c1nc(CN)no1.CC(C)S(=O)(=O)Cl>>CC(C)S(=O)(=O)NCc1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1,,ClCCl,,Cc1cccc(C)n1,,test
US20110201650A1,Cc1ccc(-c2cc(C3(O)CCC4(CC3)OCCO4)nn2-c2ccc(Cl)cc2)cc1>>Cc1ccc(-c2cc(C3(O)CCC(=O)CC3)nn2-c2ccc(Cl)cc2)cc1,,C1CCOC1,Cl,O=C([O-])O.[Na+],,test
US20080269218A1,CC(C)c1cc(Br)c(O)cc1O.CCOC(C)=O.COCCl>>COCOc1cc(OCOC)c(C(C)C)cc1Br,,CCOC(C)=O,,CCN(C(C)C)C(C)C,CN(C)C=O,test
US20070155743A1,CC(C)[C@@H](CO)C[C@H]1COC(C)(C)N1C(=O)OC(C)(C)C.CS(=O)(=O)Cl>>CC(C)[C@@H](COS(C)(=O)=O)C[C@H]1COC(C)(C)N1C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US04101658,NNC1CCS(=O)(=O)C1.O=CC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)C(NC(=O)Cc3cccs3)[C@H]2SC1>>O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(C=NNC3CCS(=O)(=O)C3)CS[C@H]12,,C1CCOC1,O,Cl,,test
US20150218106A1,COc1ccc(C=O)c(F)c1.N#Cc1cn[nH]c1N.[C-]#[N+]C1CCCC1>>COc1ccc(-c2[nH]c3c(C#N)cnn3c2NC2CCCC2)c(F)c1,,CO,,[O-][Cl+3]([O-])([O-])O,,test
US20060135483A1,COC(=O)c1ccc(CBr)cc1.COC(=O)c1cccc(Oc2cccc(-c3nnc(Nc4ccc(Cl)c(Cl)c4)o3)c2)c1>>O=C(O)c1cccc(Oc2cccc(-c3nnc(NC4=CC=C(Cl)C(Cl)(Cc5ccccc5)C4)o3)c2)c1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120177748A1,Nc1ncc(Br)cc1C(=O)NNC(=O)c1ccccc1>>Nc1ncc(Br)cc1-c1nnc(-c2ccccc2)o1,,O,,[Na+].[OH-],,test
US20110207716A1,CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3C3=CCOCC3)nc2N1C1CCCC1>>CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3C3CCOCC3)nc2N1C1CCCC1,[Pd],CO,,,,test
US04264512,CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C=CC4=C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4CCC[C@H](O)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,[Li],,test
US20090029976A1,CC(C)N1CCC(Oc2ccc3oc(C(=O)O)cc3c2)CC1.O=S1(=O)CCNCC1>>CC(C)N1CCC(Oc2ccc3oc(C(=O)N4CCS(=O)(=O)CC4)cc3c2)CC1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20070135430A1,C[C@@H](Cn1ncc2ccc3oc(C(N)=O)cc3c21)NC(=O)OCc1ccccc1.c1ccc(N2CCNCC2)nc1>>C[C@@H](Cn1ncc2ccc3oc(CN4CCN(c5ccccn5)CC4)cc3c21)NC(=O)OCc1ccccc1,,ClCCl,,O=S(Cl)Cl,,test
US05866560,C[C@]12C[C@H](F)[C@@H]3[C@H]4CCC(=O)C=C4C[C@@H](CCCCCO)[C@H]3[C@@H]1CCC2=O.ClC(Cl)(Cl)Cl>>C[C@]12C[C@H](F)[C@@H]3[C@H]4CCC(=O)C=C4C[C@@H](CCCCCCl)[C@H]3[C@@H]1CCC2=O,,CC#N,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20040024010A1,CCOC(=O)CCc1c(C=O)[nH]c(C(=O)OCC)c1C.COc1cccc(-c2ccc3c(c2)NC(=O)C3)c1>>COc1cccc(-c2ccc3c(c2)NC(=O)C3=Cc2[nH]c(C(=O)O)c(C)c2CCC(=O)O)c1,C1CCNCC1,CCO,,,,test
US20120157421A1,CC(C)(C)OC(=O)N1CCC[C@H]1C=CCCCCC(F)(F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCC[C@H]1CCCCCCC(F)(F)C(F)(F)F,O=[Pt],CO,O,[H][H],,test
US20110172237A1,O=C(CCl)Nc1noc2ccccc12.O=C(O[C@H]1CN2CCC1CC2)C1(c2cccs2)CCCCCC1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)C1(c3cccs3)CCCCCC1)C2)Nc1noc2ccccc12.[Cl-],,CC#N,,,,test
US20090042876A1,C=O.CCC(=O)[O-].Nc1ccc2[nH]c(=O)c3[nH]ccc3c2c1.[BH3-]C#N>>CCC(=O)[O-].CN(C)c1ccc2[nH]c(=O)c3[nH]ccc3c2c1,,CCO,,CC(=O)O,,test
US20090029994A1,CCCN(CC1CC1)c1ccc(C(F)(F)F)cc1CNc1ncc(Br)cn1.N#Cc1cc(CBr)cc(C(F)(F)F)c1>>CCCN(CC1CC1)c1ccc(C(F)(F)F)cc1CN(Cc1cc(C#N)cc(C(F)(F)F)c1)c1ncc(Br)cn1,,CN(C)C=O,,CC(=O)O,[H-].[Na+],test
US20090105253A1,CC(=O)c1ccccc1.CCNC(=O)c1ccc(-n2nnc(C(=O)NC3CC3)c2CP(=O)(OCC)OCC)cc1>>CCNC(=O)c1ccc(-n2nnc(C(=O)NC3CC3)c2/C=C(\C)c2ccccc2)cc1,,C1CCOC1,,O,[H-].[Na+],test
US20090005452A1,Nc1cc(F)cc(C(F)(F)F)c1.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>O=C(Nc1cc(F)cc(C(F)(F)F)c1)Nc1ccc(Cl)c(C(F)(F)F)c1,,C1CCOC1,,,,test
US20070219214A1,CC(=O)Oc1ccc(C(=O)N(C)C[C@@H](CCN2CCC(C(=O)N(C)C)(N3CCCCC3)CC2)c2ccc(Cl)c(Cl)c2)cc1>>CN(C)C(=O)C1(N2CCCCC2)CCN(CC[C@H](CN(C)C(=O)c2ccc(O)cc2)c2ccc(Cl)c(Cl)c2)CC1,,CO,,[K+].[OH-],,test
US20080015187A1,COC(=O)c1n[nH]c(C(=O)OC)c1OCc1ccccc1.O=[N+]([O-])c1ccccc1F>>COC(=O)c1nn(-c2ccccc2[N+](=O)[O-])c(C(=O)OC)c1OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080280917A1,BrBr.CC(C)(C)[Si](C)(C)Oc1ccc(CCO)cc1>>CC(C)(C)[Si](C)(C)Oc1ccc(CCBr)cc1,,CC#N,CCOCC,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05618819,BrBr.CC(=O)c1cnc2c(c1)CC(=O)N2C>>CN1C(=O)Cc2cc(C(=O)CBr)cnc21,,CC(=O)O,,,,test
US05089504,CCCC(=O)C(=CNc1ccccc1CO)C(=O)OCC.COc1ccc(C(=O)Cl)cc1>>CCCC(=O)C(=CNc1ccccc1COC(=O)c1ccc(OC)cc1)C(=O)OCC,,c1ccncc1,,,,test
US20020193414A1,COCCN.O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(NCCCl)ccc1Cl>>COCCNCCNc1ccc(Cl)c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1,,CCO,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20080132528A1,CSc1ncc2cc(-c3cc(-c4nnc(CC(C)C)o4)ccc3C)c(=O)n(C3CCCC3)c2n1.O=C(OO)c1cccc(Cl)c1>>Cc1ccc(-c2nnc(CC(C)C)o2)cc1-c1cc2cnc(S(C)=O)nc2n(C2CCCC2)c1=O,,CCOC(C)=O,ClCCl,,,test
US20120264785A1,Cc1n[nH]c2ccc(C=O)cc12.N#CC=C(N)C(F)(F)F.N#CCC(=O)C(F)F>>Cc1n[nH]c2ccc(C3C(C#N)=C(C(F)F)NC(C(F)(F)F)=C3C#N)cc12,,CC(=O)O,ClCCl,C1CCNCC1,,test
US20050054658A1,CC(C)(C)OC(=O)NC[C@H]1CC[C@@H](C(O)CCc2ccccc2)CC1>>NC[C@H]1CC[C@@H](C(O)CCc2ccccc2)CC1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20150038574A1,CC1=C(CC=O)C(C)(C)CCC1.Clc1ccc(Br)cc1Cl>>CC1=C(CC(O)c2ccc(Cl)c(Cl)c2)C(C)(C)CCC1,,CCOCC,,[Mg],,test
US20140364408A1,NNc1ccccn1.O=C(O)/C=C\n1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1>>O=C(/C=C\n1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)NNc1ccccn1,,CCOC(C)=O,ClCCl,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20090281161A1,COCCCOc1cc(C[C@@H](C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2C(=O)O)C(C)C)ccc1OC.C[Si](C)(C)CCO.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COCCCOc1cc(C[C@@H](C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2NC(=O)OCC[Si](C)(C)C)C(C)C)ccc1OC,,Cc1ccccc1,,CCN(CC)CC,,test
US20140142085A1,COC(=O)C(=O)c1c[nH]c2ccc(CNC(=O)OC(C)(C)C)cc12>>COC(=O)Cc1c[nH]c2ccc(CNC(=O)OC(C)(C)C)cc12,[Pd],O,,C1COCCO1,,test
US20160009718A1,CC=O.CCOC(=O)c1c(C)c(C(C)NC)n2ncccc12>>CCOC(=O)c1c(C)c(C(C)N(C)CC)n2ncccc12,,CC(=O)O,,[BH3-]C#N.[Na+],,test
US03983130,Nc1cc([N+](=O)[O-])ccc1O.O=Cc1ccco1>>O=[N+]([O-])c1ccc2oc(-c3ccco3)nc2c1,,CCO,,,,test
US20100216802A1,CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)[C@H](CC=O)NC(=O)OC(C)(C)C.CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCNCC4)cc3OC)nc2N1C1CCCC1>>CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(CC[C@H](NC(=O)OC(C)(C)C)C(=O)O[C@@H]5C[C@H](C)CC[C@H]5C(C)C)CC4)cc3OC)nc2N1C1CCCC1,,ClCCCl,ClCCl,O=C([O-])O.[Na+],,test
US20100273764A1,CS(=O)(=O)Nc1cc(N)cnc1Cl.Cc1nc(N)cc(-c2nccnc2F)n1>>Cc1nc(N)cc(-c2nccnc2Nc2cnc(Cl)c(NS(C)(=O)=O)c2)n1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20150232480A1,CCOC(=O)C(=O)CBr.Cc1cc(N)nc(Cl)c1C(=O)OC(C)(C)C>>CCOC(=O)c1cn2c(Cl)c(C(=O)OC(C)(C)C)c(C)cc2n1,,CCO,,,,test
US05593993,Nc1ccc(Br)cn1.S=C(n1ccnc1)n1ccnc1>>Nc1ncc(Br)cc1NC(=S)n1ccnc1,,CC#N,,,,test
US05714489,CCC(CC)CN.O=[N+]([O-])c1cc(Cl)ccc1Cl>>CCC(CC)CNc1ccc(Cl)cc1[N+](=O)[O-],C1COCCOCCOCCOCCOCCO1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06087380,CNc1ccc(C)nc1[N+](=O)[O-]>>CNc1ccc(C)nc1N,[Ni],CCOC(C)=O,,,,test
US20050159599A1,O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(Cl)cc1.O=C(OCc1ccccc1)N(CCl)CCl>>O=C(OCc1ccccc1)N1CN(C(=O)c2c(F)cccc2F)C(=O)N(c2ccc(Cl)cc2)C1,,C1CCOC1,CN(C)C=O,O,[H-].[Na+],test
US04983586,NC1(O)CCCCC1.O=C(O)c1cccnc1>>O=C(NC1CCC(O)CC1)c1cccnc1,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US20090131461A1,COc1cc2c(Sc3ccc(NC(=O)c4ccccc4)cc3)ccnc2cc1OCC[C@H](NC(=O)OC(C)(C)C)C(=O)OC1CCCC1>>COc1cc2c(Sc3ccc(NC(=O)c4ccccc4)cc3)ccnc2cc1OCC[C@H](N)C(=O)OC1CCCC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US04238611,CN1CCNCC1.O=C1Cc2ccccc2Sc2cc(Cl)c(F)cc21>>CN1CCN(C2=Cc3ccccc3Sc3cc(Cl)c(F)cc32)CC1,Cl[Ti](Cl)(Cl)Cl,c1ccccc1,,,,test
US05124324,CN1CCCC1CCO.O=C(Cl)c1c[nH]c2ccccc12>>CN1CCCC1CCOC(=O)c1c[nH]c2ccccc12,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20090074738A1,BrCc1ccc(I)cc1.Cc1cccc2c([C@@H]3O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)c[nH]c12>>Cc1cccc2c([C@@H]3O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)cn(Cc3ccc(I)cc3)c12,,CN(C)C=O,,Cl,[H-].[Na+],test
US20150045378A1,COc1ccc(C(C2CC2)C2C(=O)OC(C)(C)OC2=O)cc1O>>COc1ccc(C(CC(=O)O)C2CC2)cc1O,,CN(C)C=O,,O,,test
US20160158207A1,O=[N+]([O-])c1cc(C(F)F)c(Br)cc1OCCCl>>Nc1cc(C(F)F)c(Br)cc1OCCCl,[Fe],CC(=O)O,,,,test
US20080103123A1,Brc1ccc(Br)nc1.CC(C)(C)OC(=O)N1CCC(CN)CC1>>CC(C)(C)OC(=O)N1CCC(CNc2ccc(Br)cn2)CC1,,c1ccncc1,,,,test
US20120157430A1,CC(=O)c1cc(Cl)c(C)c(N)c1-c1cccc(F)c1.O=C(Cl)CCCCl>>CC(=O)c1cc(Cl)c(C)c(N2CCCC2=O)c1-c1cccc(F)c1,CN(C)c1ccncc1,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20040006067A1,O=[N+]([O-])c1ccccc1-c1ccncc1>>Nc1ccccc1-c1ccncc1,,CO,,Cl,,test
US05646173,C[C@@H](O)CN.Cc1ccc2c(c1)C(=O)C(CC=O)C21CCCC1>>Cc1ccc2c(c1)-c1c(ccn1C[C@@H](C)O)C21CCCC1,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,O,,test
US20060094843A1,CCI.COC(=O)C1CCCC1=O>>CCC1(C(=O)OC)CCCC1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140288045A1,CC(=O)Cl.COC(=O)c1cc(N)c(OC)cc1Cl>>COC(=O)c1cc(NC(C)=O)c(OC)cc1Cl,,ClCCl,,CCN(CC)CC,,test
US20100120844A1,CC(C)(C)OC(=O)N(CCN1Cc2ccc(F)cc2CC1Cc1ccccc1)Cc1ccccc1>>Fc1ccc2c(c1)CC(Cc1ccccc1)N(CCNCc1ccccc1)C2,,CCOC(C)=O,Cl,,,test
US04962115,CCOC(=O)N1CC[C@H](NC(=O)c2cc(Cl)c(N)cc2OC)[C@H](OC)C1>>COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCNC[C@H]1OC,,CC(C)O,,[K+].[OH-],,test
US20030199550A1,CN(C[C@@H]1CC[C@@H](OCCCCO)CC1)C(=O)OC(C)(C)C.O=C(Cl)Oc1ccc(Cl)cc1>>CN(C[C@@H]1CC[C@@H](OCCCCO)CC1)C(=O)Oc1ccc(Cl)cc1,,CO,O,Cl,,test
US20100111890A1,C=C(C)CC(CC)(C(=O)OC)C(=O)OC>>CCC1CC(C)(C)OC1=O,,CO,O,O=S(=O)(O)O,[Na+].[OH-],test
US20110312963A1,COCC(=O)Nc1cc(Oc2ccc([N+](=O)[O-])c(C)c2C)ccn1>>COCC(=O)Nc1cc(Oc2ccc(N)c(C)c2C)ccn1,[Pt],CC(=O)O,,CO,[H][H],test
US20040110815A1,COCCC(=O)COC.COc1ccc(-c2cccc3cn(C)nc23)c(C)c1>>COCCC(O)(COC)c1c2cccc(-c3ccc(OC)cc3C)c2nn1C,,C1CCOC1,CCOC(C)=O,[Li]CCCC,,test
US20120214837A1,COc1ccc2nc(NCc3ccccc3)c(C=O)cc2c1>>COc1ccc2nc(NCc3ccccc3)c(CO)cc2c1,,C1CCOC1,,,,test
US20120028931A1,CC(C)(C)OC(=O)N1CCC(=Cc2nc(-c3ccccc3)no2)CC1>>C(=C1CCNCC1)c1nc(-c2ccccc2)no1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20100280007A1,CCOC(=O)CBr.COc1ccc(C(=O)Cc2ccccc2)cc1>>CCOC(=O)CC(C(=O)c1ccc(OC)cc1)c1ccccc1,,Cc1ccccc1,,,,test
US20160193218A1,CN(C)C(=O)[C@H]1CC[C@@H](NC(=O)OC(C)(C)C)CC1.Cl>>CN(C)C(=O)[C@@H]1CC[C@H](N)CC1.Cl,,CO,,,,test
US20040209921A1,COC(=O)c1cc(C#N)ccc1CBr.Cc1cnc(CN[C@@H]2CCCc3cccnc32)c(C)c1>>COC(=O)c1cc(C#N)ccc1CN(Cc1ncc(C)cc1C)C1CCCc2cccnc21,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04237129,COC(=O)C1SCCN1C(=O)C(C)CSC(C)=O>>CC(CS)C(=O)N1CCSC1C(=O)O,,CO,,[Na+].[OH-],,test
US20070203206A1,BrCc1ccccc1.O=C(O)c1ccc([N+](=O)[O-])c(F)c1>>O=C(OCc1ccccc1)c1ccc([N+](=O)[O-])c(F)c1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US06191124B1,Cc1csc2ncc(C(=O)CCc3ccccc3)n12>>Cc1csc2ncc(C(O)CCc3ccccc3)n12,,CCO,,[BH4-].[Na+],,test
US20080227770A1,CCOC(=O)CSc1nc(C[C@H]2O[C@H](c3cccc(OC)c3OC)c3cc(Cl)ccc3N(CC(C)(C)C)C2=O)ns1>>COc1cccc([C@H]2O[C@H](Cc3nsc(SCC(=O)O)n3)C(=O)N(CC(C)(C)C)c3ccc(Cl)cc32)c1OC,,C1CCOC1,CCO,[Na+].[OH-],,test
US20050176701A1,CC(C)(C)C1(c2ccc(CCC3(C4CCCC4)CC(=O)CC(=O)O3)cc2)OCCO1>>CC(C)(C)C(=O)c1ccc(CCC2(C3CCCC3)CC(=O)CC(=O)O2)cc1,,CC(C)=O,,,,test
US04778796,O=C1c2ccccc2C(=O)N1CC=CCBr.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>O=C1c2ccccc2C(=O)N1CC=CCN1CCN(C(c2ccccc2)c2ccccc2)CC1,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20110312962A1,NCc1ccc(F)cc1.O=[N+]([O-])c1ccc(Cl)nc1N1CCOCC1>>O=[N+]([O-])c1ccc(NCc2ccc(F)cc2)nc1N1CCOCC1,,CC#N,,CCN(CC)CC,Cl,test
US20100286145A1,CC(=O)Cl.CC(C)(C)OC(=O)NCc1cccc(N)c1>>CC(=O)Nc1cccc(CNC(=O)OC(C)(C)C)c1,,ClCCl,,CCN(CC)CC,,test
US04983211,O=C1C=C(O)CC(c2cccc(OCc3ccccc3)c2)C1>>O=C1C=C(O)CC(c2cccc(O)c2)C1,[Pd],CCO,,,,test
US20120309728A1,COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C[C@H](O)C4CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C.O=C(Cl)c1ccccc1>>COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C[C@H](OC(=O)c4ccccc4)C4CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C,,c1ccncc1,,CCOC(C)=O,O=C([O-])O.[Na+],test
US20050065162A1,COc1ccc(C=O)cc1OC.COc1nc(N2CCNCC2)ccc1Br>>COc1ccc(CN2CCN(c3ccc(Br)c(OC)n3)CC2)cc1OC,CC(=O)O,Cc1ccccc1,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20110076291A1,CC(C)(O)C(=O)O.CC(C)n1ncnc1-c1nc2c(s1)CCOc1cc(C3CNC3)ccc1-2>>CC(C)n1ncnc1-c1nc2c(s1)CCOc1cc(C3CN(C(=O)C(C)(C)O)C3)ccc1-2,,CN(C)C=O,,O=C(O)C(F)(F)F,,test
US20110076291A1,CC(=O)Cl.Fc1ccc(-n2ncnc2-c2cc3c(s2)-c2nc(N4CC5CC4CN5)ccc2OCC3)c(F)c1>>CC(=O)N1CC2CC1CN2c1ccc2c(n1)-c1sc(-c3ncnn3-c3ccc(F)cc3F)cc1CCO2,,C1CCOC1,,CCN(C(C)C)C(C)C,O,test
US20020052482A1,C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O.O=C(Oc1c(F)c(F)cc(F)c1F)C(F)(F)F>>O=C(CCNC(=O)OCC1c2ccccc2-c2ccccc21)Oc1c(F)c(F)cc(F)c1F,,ClCCl,,CCN(CC)CC,,test
US20040127494A1,CC(C)(C)OC(=O)CBr.CC(C)C[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)C(N)=O>>CC(C)C[C@H](C(N)=O)N(CC(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Cl)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110245227A1,CC(C)(C)OC(=O)N1CCC(Oc2ccn(-c3cccnc3)c(=O)c2)CC1.Cl>>Cl.O=c1cc(OC2CCNCC2)ccn1-c1cccnc1,,CO,,,,test
US05686442,COc1ccc(Cn2nnc(C(=O)O)c2C(=O)c2cc(OC)c(C)cc2[N+](=O)[O-])cc1>>COc1ccc(Cn2nnc(C(=O)O)c2C(=O)c2cc(OC)c(C)cc2N)cc1,[Pd],CCO,CCOC(C)=O,[H][H],,test
US20070015788A1,CCCCCC(=O)CC.CCO.NO>>CCCCCC(CC)=NOC,,CCO,,Cl,c1ccncc1,test
US20030225113A1,CSc1nc(-c2cccc(N)c2)c2c(N)c(C(=O)NC(C)(C)C)sc2n1.Cc1ccc(S(=O)(=O)Cl)cc1>>CSc1nc(-c2cccc(NS(=O)(=O)c3ccc(C)cc3)c2)c2c(N)c(C(=O)NC(C)(C)C)sc2n1,,ClCCl,c1ccncc1,,,test
US20040110773A1,CN1CCNCC1.COc1ccc(N2C(=O)N(c3cccc(C#N)c3)c3nc(Nc4cccc(CCOS(C)(=O)=O)c4)ncc3C2C)cc1>>COc1ccc(N2C(=O)N(c3cccc(C#N)c3)c3nc(Nc4cccc(CCN5CCN(C)CC5)c4)ncc3C2C)cc1,,CCOC(C)=O,,,,test
US20060178375A1,BrC1CCCC1.O=c1ccc(-c2cnc(OC3CCN(C4CCCC4)CC3)nc2)c[nH]1>>c1cc(OC2CCCC2)ncc1-c1cnc(OC2CCN(C3CCCC3)CC2)nc1,,O,,CN(C)C=O,[H-].[Na+],test
US20040014971A1,O=C(Nc1ccc(N2CCN(Cc3ccccc3)CC2)cc1)c1ccccc1-c1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc(N2CCNCC2)cc1)c1ccccc1-c1ccc(C(F)(F)F)cc1,[Pd],C1CCOC1,CO,[H][H],,test
US04346101,CN(C)C1(CNC(=O)c2ccc(Cl)c(Cl)c2)CCC2(CC1)OCCO2.O=C(Cl)c1ccc(C(F)(F)F)cc1>>CN(C)C1(CNC(=O)c2ccc(C(F)(F)F)cc2)CCC2(CC1)OCCO2,,C1CCOC1,,CCN(CC)CC,,test
US20120225867A1,CC(C)(C)C(=O)OC(=O)C(C)(C)C.CC(O)c1cc(C(=O)N[C@@H](C)Cn2ccc(-c3ccc(C#N)c(Cl)c3)n2)[nH]n1>>CC(OC(=O)C(C)(C)C)c1cc(C(=O)N[C@@H](C)Cn2ccc(-c3ccc(C#N)c(Cl)c3)n2)[nH]n1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20100249418A1,CC(Br)C(=O)c1ccc(O)cc1.Nc1ccc(I)cn1>>Br.Cc1c(-c2ccc(O)cc2)nc2ccc(I)cn12,,CC#N,,,,test
US20100298377A1,CC(C)(C)OC(=O)N1CCCCC1C=O.Clc1cc(Cl)cc(Br)c1>>CC(C)(C)OC(=O)N1CCCCC1C(O)c1cc(Cl)cc(Cl)c1,,C1CCOC1,CCOC(C)=O,O,,test
US20160083379A1,C=C(C)COc1cc([N+](=O)[O-])ccc1Br.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C=C(C)COc1cc(NC(=O)OC(C)(C)C)ccc1Br,[Fe],CO,,[Cl-].[NH4+],,test
US05047540,CCCCCCCCCCCCCCCCOS(C)(=O)=O.OCC1COC(c2ccccc2)OC1>>CCCCCCCCCCCCCCCCOCC1COC(c2ccccc2)OC1,,c1ccccc1,,CCOC(C)=O,[H-].[Na+],test
US20140121208A1,C#CC(C)(C)C.Nc1cc(F)c([N+](=O)[O-])cc1Br>>CC(C)(C)C#Cc1cc([N+](=O)[O-])c(F)cc1N,[Cu]I,Cc1ccccc1,O,CCN(CC)CC,,test
US20140088079A1,CC(C)(C)[Si](OCc1cc(C2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)c2c(c1Cl)CCO2)(c1ccccc1)c1ccccc1>>OCc1cc(C2O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)c2c(c1Cl)CCO2,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080021012A1,CC(C)(C)OC(=O)N1CCC(CC(=O)c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)CC1>>O=C(CC1CCNCC1)c1ccc(-c2ccc(N3C[C@H](Cn4ccnn4)OC3=O)cc2F)cn1,,C1COCCO1,,Cl,,test
US06143894,COc1cc[nH]c(=O)c1C#N.O=[N+]([O-])O>>O=[N+]([O-])c1c(O)ccnc1O,,O,,CC(=O)O,,test
US05145840,BrBr.[N-]=[N+]=N[C@]1(O)C[C@H](n2ccc(=O)[nH]c2=O)O[C@@H]1CO>>[N-]=[N+]=N[C@]1(O)C[C@H](n2cc(Br)c(=O)[nH]c2=O)O[C@@H]1CO,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20110053940A1,Cn1ccc([C@@H]2CCN(C(=O)OC(C)(C)C)C[C@H]2C(=O)N(Cc2cc(Br)cc(SCCO)c2)C2CC2)cc1=O>>Cn1ccc([C@@H]2CCNC[C@H]2C(=O)N(Cc2cc(Br)cc(SCCO)c2)C2CC2)cc1=O,,ClCCl,,Cl,,test
US20130281433A1,CCc1c[nH]nc1N.O=CC(Br)C=O>>CCc1cnn2cc(Br)cnc12,,CCO,,CC(=O)O,,test
US20080312226A1,CCc1nnc(N)o1.O=C(Cl)OCC(Cl)(Cl)Cl>>CCc1nnc(NC(=O)OCC(Cl)(Cl)Cl)o1,,C1CCOC1,,O,c1ccncc1,test
US04203932,CC(C)OP(=O)(NN)OC(C)C.CCOP(=O)(NNC(C)=O)OCC>>CC(=O)NNP(=O)(OC(C)C)OC(C)C,,c1ccncc1,,,,test
US20160122335A1,C[C@H]1CCCCN1C(=O)c1nc(CO)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c1Cl>>C[C@H]1CCCCN1C(=O)c1nc(C=O)sc1-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)c(Cl)c1Cl,,CC(C)=O,,,,test
US20100240702A1,CCOC(=O)C[C@H](CCc1ccccc1)Nc1cc(C)ccc1N.O=C(n1ccnc1)n1ccnc1>>CCOC(=O)C[C@H](CCc1ccccc1)n1c(=O)[nH]c2ccc(C)cc21,,C1CCOC1,ClCCl,,,test
US20140228343A1,Nc1cc[nH]n1.O=Cc1cccc(OCC(O)CN2CCc3ccccc3C2)c1>>OC(COc1cccc(CNc2cc[nH]n2)c1)CN1CCc2ccccc2C1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20110039843A1,Fc1cnccc1-c1nc2cc(C(F)(F)F)ccc2o1.c1cn[nH]c1>>FC(F)(F)c1ccc2oc(-c3ccncc3-n3cccn3)nc2c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20050261303A1,COc1cnc2cc([N+](=O)[O-])ccc2n1>>COc1cnc2cc(N)ccc2n1,[Fe],CO,,[Cl-].[NH4+],,test
US20150064196A1,CCOC(=O)CC(=N)N.COC(=O)c1ccc(C(=O)CBr)cc1>>CCOC(=O)c1cc(-c2ccc(C(=O)OC)cc2)[nH]c1N,,CCO,,Cl,,test
US20160039815A1,Cn1c(=O)n(CCCO[Si](C)(C)C(C)(C)C)c(=O)c2cc(Cl)ncc21.O=Cc1ccc(Cl)cc1>>Cn1c(=O)n(CCCO[Si](C)(C)C(C)(C)C)c(=O)c2c(C(O)c3ccc(Cl)cc3)c(Cl)ncc21,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US04619931,COc1ccc(N2CCN(S(=O)(=O)c3ccc(C)cc3)CC2C)cc1>>COc1ccc(N2CCNCC2C)cc1,,O,,O=S(=O)(O)O,[Na+].[OH-],test
US20080275041A1,COC(=O)c1ccc2[nH]c(O)c(-c3ccc(CN4CCOCC4)cn3)c2c1.CS(=O)(=O)CCN.Cl>>CS(=O)(=O)CCNC(=O)c1ccc2[nH]c(O)c(-c3ccc(CN4CCOCC4)cn3)c2c1.Cl,,O=C([O-])O,[Na+],,,test
US20020013460A1,CNC(=O)c1ccsc1C.N#Cc1ccc(C2OCCO2)cc1>>O=c1[nH]c(-c2ccc(C3OCCO3)cc2)cc2sccc12,,C1CCOC1,,[Li]CCCC,,test
US20060128790A1,Cc1cc2c(c(C)c1O)CCC1(CCC1)O2.O=S(=O)(Cl)Cl>>Cc1c(O)c(C)c2c(c1Cl)OC1(CCC1)CC2,,CCOCC,,CCOC(C)=O,,test
US20100144793A1,Cc1cc(NCC(=O)Nc2cc(C)n(C3CCCCO3)n2)nn1C1CCCCO1>>Cc1cc(NCC(=O)Nc2cc(C)[nH]n2)n[nH]1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100267696A1,O=C(OCc1ccccc1)N1CCC(c2cc(C(=O)N3CCCCCC3)cs2)CC1.O=C1CCC(=O)N1Cl>>O=C(OCc1ccccc1)N1CCC(c2cc(C(=O)N3CCCCCC3)c(Cl)s2)CC1,,CC(=O)O,,,,test
US20070219217A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1cnc(C(F)(F)F)nc1>>O=S(=O)(Oc1cnc(C(F)(F)F)nc1)C(F)(F)F,,Cc1ccccc1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20130085157A1,Cc1ccc(N(C)C(=O)c2sc(NN)nc2-c2ccccc2)cc1Cl.S=C=S>>Cc1ccc(N(C)C(=O)c2sc3nnc(S)n3c2-c2ccccc2)cc1Cl,,CO,,[K+].[OH-],,test
US20050014754A1,CCOC(=O)c1cc(C(=O)c2ccc(F)cc2)c2ccccn12>>O=C(c1ccc(F)cc1)c1ccn2ccccc12,,CO,,[K+].[OH-],,test
US20070244132A1,Clc1ncnc2cc[nH]c12.OCc1ccc(CCl)cc1>>OCc1ccc(Cn2ccc3ncnc(Cl)c32)cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04654343,BrCC1CC1.CC(=O)Nc1cccc(-c2ccc3nnc(C)n3n2)c1>>CC(=O)N(CC1CC1)c1cccc(-c2ccc3nnc(C)n3n2)c1,,O,,CN(C)C=O,[H-].[Na+],test
US04254034,C1COCCOCCOCCOCCOCCO1.COC(=O)C(=O)OC>>C1COCCOCCOCCOCCOCCO1.COC(=O)C(=O)OC,,CCOCC,,,,test
US20100210680A1,CB1OB(C)OB(C)O1.Clc1c(Br)ccc2c1CO[C@H]1CCNC[C@@H]21>>Cc1ccc2c(c1Cl)CO[C@H]1CCNC[C@@H]21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US20090042890A1,CCOC(=O)c1nc(NC[C@@H]2CCCN2)nc2c1[nH]c(=O)n2-c1ccccc1OC.CCOC(=O)c1nc(NC[C@@H]2CCCN2C(=O)OC(C)(C)C)nc2c1[nH]c(=O)n2-c1ccccc1OC>>COc1ccccc1-n1c(=O)[nH]c2c(C(N)=O)nc(NC[C@@H]3CCCN3)nc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US05468742,C=C(C)C#C[Sn](CCCC)(CCCC)CCCC.CCOC(=O)c1cn(C2CC2)c2c(Br)c(F)c(F)cc2c1=O>>C=C(C)C#Cc1c(F)c(F)cc2c(=O)c(C(=O)OCC)cn(C3CC3)c12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US06162824,Cc1cccc([Mg]Cl)c1.O=C1c2ccccc2-c2ccccc21>>Cc1cccc(C2(O)c3ccccc3-c3ccccc32)c1,,C1CCOC1,,CCOCC,,test
US20050009900A1,COC(=O)c1cc(-c2csc(C)n2)ccc1Cl>>Cc1nc(-c2ccc(Cl)c(C(=O)O)c2)cs1,,CC(C)(C)O,,[Na+].[OH-],,test
US04999356,NNc1ccc(C(F)(F)F)cc1.O=C(Cl)c1ccccc1F>>O=C(NNc1ccc(C(F)(F)F)cc1)c1ccccc1F,,c1ccncc1,,,,test
US20030195259A1,CCC=O.CCc1cc(Br)ccc1O[Si](C)(C)C(C)(C)C>>CCc1cc(C(O)CC)ccc1O[Si](C)(C)C(C)(C)C,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20150158846A1,CCC(=O)Cl.Cn1cc(Br)cc(Nc2cccc(OCCN)n2)c1=O>>CCC(=O)NCCOc1cccc(Nc2cc(Br)cn(C)c2=O)n1,,ClCCl,,CCN(CC)CC,Cl,test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cccnc3Nc3ccc(F)c(OC)c3)n2)cc1>>COc1cc(Nc2ncccc2-c2nc(C)nc(N)n2)ccc1F,,O=C(O)C(F)(F)F,,,,test
US20090324581A1,COC(=O)C1CN(C(=O)N2CCc3cc(OCc4cc(-c5ccccc5)c(C(F)(F)F)s4)ccc32)C1>>O=C(O)C1CN(C(=O)N2CCc3cc(OCc4cc(-c5ccccc5)c(C(F)(F)F)s4)ccc32)C1,,C1CCOC1,CO,[Na+].[OH-],,test
US20090082358A1,O=C(Nc1ccc(F)cc1)N1CCc2c(Cl)ccnc2[C@H]1c1ccc(C(F)(F)F)cc1.OB(O)c1ccc(F)cc1>>O=C(Nc1ccc(F)cc1)N1CCc2c(-c3ccc(F)cc3)ccnc2[C@H]1c1ccc(C(F)(F)F)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20050054733A1,Cc1c(F)ccc(Br)c1F.N#C[Cu]C#N>>Cc1c(F)ccc(C#N)c1F,I[Cu]I,CN(C)C=O,,,,test
US20090197834A1,CC(=O)COc1cn(C2CCCC2)c2cc(NC3CCCCC3)c(F)cc2c1=O.CCOC(=O)CP(=O)(OCC)OCC>>CCOC(=O)/C=C(\C)COc1cn(C2CCCC2)c2cc(NC3CCCCC3)c(F)cc2c1=O,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20150368187A1,ClCC1CO1.OCc1ccccc1O>>COc1cccc(CO)c1C1CO1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06242611B1,CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)N1CCCCO.II>>CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)N1CCCCI,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04247700,C=O.N#CCC(=O)O.OC1(c2ccccc2)CCNCC1>>C=C(C#N)CN1CCC(O)(c2ccccc2)CC1,,C1COCCO1,,O=C=O,,test
US05366987,CCCCCCCCCCC=Cc1cnn(C(C(=O)Nc2c(OC)cc(OC)cc2OC)c2ccccc2)c1>>CCCCCCCCCCCCc1cnn(C(C(=O)Nc2c(OC)cc(OC)cc2OC)c2ccccc2)c1,[Pd],C1CCOC1,,[H][H],,test
US06201006B1,CCOC(=O)C(C(=O)N1CCC[C@H]1CCc1cc2ccc(C(=N)N)cc2n1CC)C1CCCC1>>CCn1c(CC[C@@H]2CCCN2C(=O)C(C(=O)O)C2CCCC2)cc2ccc(C(=N)N)cc21,,CCO,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[Na+].[OH-],test
US20090069297A1,CCN(CC)S(F)(F)F.COc1cnc2c(Oc3ccc(Nc4nnc(-c5cc(CO)cs5)c5ccccc45)cc3)ccnc2c1>>COc1cnc2c(Oc3ccc(Nc4nnc(-c5cc(CF)cs5)c5ccccc45)cc3)ccnc2c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20160222047A1,C1=COc2ccccc2O1.O=C(Cl)c1cc(I)ccc1Br>>O=C(c1ccc2c(c1)OCCO2)c1cc(I)ccc1Br,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20070032472A1,ClC[C@H]1CO1.Nc1ccc(N2CCOCC2)c(F)c1>>O[C@@H](CCl)CNc1ccc(N2CCOCC2)c(F)c1,,CC(C)O,,,,test
US06124283,CN1CCN(c2cccc3c2C[C@H](N)CC3)CC1.N#Cc1ccc(C(=O)Cl)cc1>>CN1CCN(c2cccc3c2C[C@H](NC(=O)c2ccc(C#N)cc2)CC3)CC1,,ClCCl,,CCN(CC)CC,,test
US20150175530A1,COC(=O)[C@@H](NC(=O)c1ccc(C#CC#CC(CO[Si](C)(C)C(C)(C)C)OC)cc1)C(C)(C)NC(=O)OC(C)(C)C>>COC(=O)[C@@H](NC(=O)c1ccc(C#CC#CC(CO)OC)cc1)C(C)(C)N,,CO,,Cl,O=C([O-])O.[Na+],test
US04946921,C=C(C)c1cccc(O)c1.CC(=O)OC(C)=O>>C=C(C)c1cccc(OC(C)=O)c1,,CCOCC,,c1ccncc1,,test
US04673676,Cc1cncc2cc([N+](=O)[O-])ccc12.OO>>Cc1c[n+]([O-])cc2cc([N+](=O)[O-])ccc12,,CC(=O)O,,,,test
US20010007875A1,CC(=O)COc1ccccc1.O=C1CSC(=O)N1>>CC(COc1ccccc1)=C1SC(=O)NC1=O,,Cc1ccccc1,O,C1CCNCC1,CC(=O)O,test
US05107004,CC(C)(C)Cc1ccc(C(=O)c2ccccc2C(=O)O)cc1>>CC(C)(C)Cc1ccc2c(c1)C(=O)c1ccccc1C2=O,,O,,O=S(=O)(O)O,,test
US20070054898A1,Cn1c(=O)c(C#N)c(N2CCNCC2)c2cc(F)ccc21.O=C(Cl)c1ccco1>>Cn1c(=O)c(C#N)c(N2CCN(C(=O)c3ccco3)CC2)c2cc(F)ccc21,,c1ccncc1,,,,test
US20130231328A1,CN(C(=O)OC(C)(C)C)C1CCC(Oc2ncnc3sc4c(c23)[C@@H](C[C@H](O)c2ccn(COCC[Si](C)(C)C)n2)CC4)CC1.Cl>>CNC1CCC(Oc2ncnc3sc4c(c23)[C@@H](C[C@H](O)c2cc[nH]n2)CC4)CC1.Cl,,ClCCl,,,,test
US20130280245A1,COc1ccc(B(O)O)cc1.Clc1ccc(Br)cn1>>COc1ccc(-c2ccc(Cl)nc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20160009718A1,C1COCCN1.CCOC(=O)c1c(C)c(C(=O)O)n2ncccc12>>CCOC(=O)c1c(C)c(C(=O)N2CCOCC2)n2ncccc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05151435,CCc1nc2c(C)cc(C)nc2n1Cc1ccc2[nH]ccc2c1.N#Cc1ccccc1CBr>>CCc1nc2c(C)cc(C)nc2n1Cc1ccc2c(ccn2Cc2ccccc2C#N)c1,,CN(C)C=O,,[H-].[Na+],,test
US20150031541A1,CSC1CNCCC1C#N.Cc1cc(C(F)(F)F)nn1CC(=O)O>>CSC1CN(C(=O)Cn2nc(C(F)(F)F)cc2C)CCC1C#N,,CN(C)C=O,O,CCN(CC)CC,Cl,test
US05872137,BrCCCCBr.Oc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl>>ClC(Cl)=CCOc1cc(Cl)c(OCCCCBr)c(Cl)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070027177A1,COc1ccc2c(=O)n3c(c(-c4cccc(F)c4)c2c1)C(=O)CCC3.NO>>COc1ccc2c(=O)n3c(c(-c4cccc(F)c4)c2c1)/C(=N/O)CCC3,,c1ccncc1,,Cl,,test
US20020061883A1,CC(C)(C)c1ccc(N=C=S)cc1.CNOCC(=O)O>>CN(OCC(=O)O)C(=S)Nc1ccc(C(C)(C)C)cc1,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20090312368A1,NS(=O)(=O)Cc1ccccc1.O=C(OCc1ccccc1)N1CCC(S(=O)(=O)Cl)CC1>>O=C(OCc1ccccc1)N1CCC(S(=O)(=O)NS(=O)(=O)Cc2ccccc2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,[Cl-].[NH4+],test
US06258813B1,Fc1ccc(-c2cncc(CCl)c2)cc1.c1cnc(N2CCNCC2)nc1>>Fc1ccc(-c2cncc(CN3CCN(c4ncccn4)CC3)c2)cc1,,CC#N,,,,test
US04977272,C1CCOC1.C=CCOC(=O)[C@@H](N)CC(C)C.COC(OC)OC.NO.[N-]=C=O.c1ccncc1>>C=CCOC(=O)C(CC(C)C)NC(=O)Nc1ccc(C=NO)cc1,,CO,,Cl,,test
US20110053897A1,C=C(OCC)c1cc(Nc2cc3ccn(CCO)c(=O)c3c(NC(C)(C)C)n2)ncn1>>CC(=O)c1cc(Nc2cc3ccn(CCO)c(=O)c3c(NC(C)(C)C)n2)ncn1,,CO,,Cl,,test
US20080096930A1,BrCc1ccc(I)cc1.CC(=O)c1ccc(O)c(Cl)c1O>>CC(=O)c1ccc(OCc2ccc(I)cc2)c(Cl)c1O,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20160221945A1,O=C1c2ccccc2C(=O)N1Cc1cc(-c2cnc(C(F)(F)F)nc2)c(Cl)cn1>>NCc1cc(-c2cnc(C(F)(F)F)nc2)c(Cl)cn1,,CO,,NN,O,test
US20160272632A1,CC(C)(C)OC(=O)C1CCC(=CC#N)CO1.Nc1n[nH]c2ccnc(OCc3ccccc3)c12>>CC(C)(C)OC(=O)C1CCC(CC#N)(n2nc(N)c3c(OCc4ccccc4)nccc32)CO1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20150368195A1,O=C(C=Cc1ccc2c(c1)CCN2S(=O)(=O)c1ccc([N+](=O)[O-])cc1)NO>>Nc1ccc(S(=O)(=O)N2CCc3cc(C=CC(=O)NO)ccc32)cc1,[Fe],CC(C)O,O,[Cl-].[NH4+],,test
US20120226053A1,Cl.NC(=O)[C@@H]1CC[C@H](c2ccc(OCc3ccccc3F)cc2)N1>>Cl.NC(=O)[C@@H]1CC[C@H](c2ccc(OCc3ccccc3F)cc2)N1,,CCOC(C)=O,CO,C1COCCO1,,test
US20090118431A1,CC12CC3(C)CC(CC(Br)Br)(C1)CC(C14CC5(C)CC(C)(CC(CC(Br)Br)(C5)C1)C4)(C2)C3>>C#CC12CC3(C)CC(C)(C1)CC(C14CC5(C)CC(C)(CC(C#C)(C5)C1)C4)(C3)C2,,O,,CC(C)(C)[O-].[K+],,test
US20110306612A1,CC1(C)OCC(CO)O1.Nc1ccnc(Cl)n1>>CC1(C)OCC(COc2nccc(N)n2)O1,,C1CCOC1,,[H-].[Na+],,test
US05958957,O=C1CSC(=O)N1.O=Cc1cccc(OCc2ccc(-c3ccccc3)cc2)c1>>O=C1NC(=O)C(=Cc2cccc(OCc3ccc(-c4ccccc4)cc3)c2)S1,,CCO,,C1CCNCC1,,test
US20060128715A1,CC(C)(C)OC(=O)NC1(c2cccc(C(C)(C)C)c2)CCC(=O)CC1.CN(C)C(OC(C)(C)C)N(C)C>>CN(C)/C=C1\CC(NC(=O)OC(C)(C)C)(c2cccc(C(C)(C)C)c2)CCC1=O,,Cc1ccccc1,,,,test
US05922882,O=[N+]([O-])c1cc(Cl)ccc1N=Nc1cc(CCO)ccc1O>>OCCc1ccc(O)c(-n2nc3ccc(Cl)cc3n2)c1,[Zn],[Na+],[OH-],,,test
US20090181963A1,CCn1nnc2c(N3CCOCC3)nc(-c3ccc(N)cc3)nc21.Nc1ccc(CCO)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCn1nnc2c(N3CCOCC3)nc(-c3ccc(NC(=O)OCCc4ccc(N)cc4)cc3)nc21,,ClCCl,,CCN(CC)CC,,test
US20140213554A1,CC(C)(C)OC(=O)N1CCN(c2cccc(-c3n[nH]c4ncc([N+](=O)[O-])cc34)c2)CC1>>CC(C)(C)OC(=O)N1CCN(c2cccc(-c3n[nH]c4ncc(N)cc34)c2)CC1,[Pd],CO,ClCCl,[H][H],,test
US20040220216A1,CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2ccc3c(c2)cc(B(O)O)n3C(=O)OC(C)(C)C)CC1.O=c1[nH]c2ccccc2cc1I>>O=c1[nH]c2ccccc2cc1-c1cc2cc(S(=O)(=O)N3CCNCC3)ccc2[nH]1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US20040167118A1,CC(C)(C)N.O=C1CCC(=O)O1>>CC(C)(C)NC(=O)CCC(=O)O,,ClCCl,,,,test
US20090233903A1,CC1(C)CC(CC#N)(n2cc(-c3ncnc4c3ccn4COCC[Si](C)(C)C)cn2)C1>>CC1(C)CC(CC#N)(n2cc(-c3ncnc4[nH]ccc34)cn2)C1,,CO,,NCCN,O=C(O)C(F)(F)F,test
US05302712,CI.c1cc2[nH]ccn2n1>>Cn1ccn2nccc12,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20050119279A1,O=C1N(c2cc(Cl)cc(Cl)c2)C(=O)[C@]2(Cc3ccc(Br)cc3)C[C@@H](O)CN12>>O=C1CN2C(=O)N(c3cc(Cl)cc(Cl)c3)C(=O)[C@]2(Cc2ccc(Br)cc2)C1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20080045544A1,CC(C)(C)OC(=O)N1CCC(N)CC1.FC(F)(F)c1ccc(Cl)nc1>>CC(C)(C)OC(=O)N1CCC(Nc2ccc(C(F)(F)F)cn2)CC1,,CC(=O)N(C)C,,[Na+].[OH-],,test
US20090198063A1,COc1cnc2ccc(=O)n(CCN3CCC(NC(=O)OC(C)(C)C)CC3)c2c1.Cl>>COc1cnc2ccc(=O)n(CCN3CCC(N)CC3)c2c1.Cl,,CCO,,,,test
US05374641,COC(=O)Cc1ccc(CC(=O)c2cccnc2)cc1.O=C[O-].[NH4+]>>COC(=O)Cc1ccc(CC(NC=O)c2cccnc2)cc1,,O,,,,test
US09273028B2,Cc1ccc(S(=O)(=O)n2ccc3c(N(C)[C@@H]4CCCN(Cc5ccccc5)C4)ncnc32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(N(C)[C@@H]4CCCNC4)ncnc32)cc1,[Pd],CO,,O=C[O-].[NH4+],,test
US20100298384A1,O=[N+]([O-])c1cccc(F)c1F.OCc1c[nH]cn1>>O=[N+]([O-])c1ccc(-n2cnc(CO)c2)c(F)c1,,O,,CCN(C(C)C)C(C)C,,test
US20120165310A1,C1CSCCN1.Cc1ccc(S(=O)(=O)OC[C@@H]2C[C@H](n3cc(-c4cccc(OCc5ccccc5)c4)c4c(N)ncnc43)C2)cc1>>Nc1ncnc2c1c(-c1cccc(OCc3ccccc3)c1)cn2[C@@H]1C[C@H](CN2CCSCC2)C1,,CN(C)C=O,,,,test
US20040132727A1,COc1cc2ncnc(Oc3ccc(N)c([N+](=O)[O-])c3)c2cc1OC.NCCN1CCCCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2ncnc(Oc3ccc(NC(=O)NCCN4CCCCC4)c([N+](=O)[O-])c3)c2cc1OC,,ClC(Cl)Cl,O,CCN(CC)CC,,test
US20080076773A1,CC(C)(C)OC(=O)N1CC[C@H](c2cc(F)c(F)cc2F)[C@@H](C(=O)O)C1.OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1CC[C@H](c2cc(F)c(F)cc2F)[C@@H](NC(=O)OCc2ccccc2)C1,,Cc1ccccc1,,CCN(CC)CC,,test
US20080076773A1,Clc1ccc(Cl)nn1.NNC(N)=O>>O=c1[nH]nc2ccc(Cl)nn12,Cl,CCO,O,,,test
US06127529,CCCCCC(Br)Br.Cc1cc(C)nc(C)c1>>Cc1cc(CCCCCCCBr)cc(C)n1,,C1CCOC1,C1CCOC1,N,,test
US20040049039A1,COC(OC)N(C)C.Cc1ncccc1-n1c(C)nc2ccc(F)cc2c1=O>>Cc1ncccc1-n1c(C=CN(C)C)nc2ccc(F)cc2c1=O,,CN(C)C=O,,,,test
US04946843,CCOCCn1c(CN2CCNCC2)nc2cccnc21.c1ccc(OCC2CO2)cc1>>CCOCCn1c(CN2CCN(CC(O)COc3ccccc3)CC2)nc2cccnc21,,CC(C)O,,,,test
US20120220572A1,CC(C)(C)OC(=O)N1Cc2cc(N)ccc2C2(CC2)C1.O=C(O)C(F)(F)F>>Nc1ccc2c(c1)CNCC21CC1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20120053180A1,CS(=O)(=O)Cl.CS(=O)(=O)c1ccc(CO)cc1>>CS(=O)(=O)c1ccc(CCl)cc1,,ClCCl,,CCN(CC)CC,,test
US20140081025A1,CCN(CCC#N)C(=O)OC(C)(C)C.NO>>CCN(CCC(N)=NO)C(=O)OC(C)(C)C,,CCO,,,,test
US20050043388A1,NNC(=O)COc1ccc(I)cc1.O=C1Nc2ccc(I)cc2C1=O>>O=C(COc1ccc(I)cc1)NN=C1C(=O)Nc2ccc(I)cc21,,CC(=O)O,,,,test
US20140187553A1,Clc1cncc(Cl)n1.FC1(F)CCNCC1>>FC1(F)CCN(c2cncc(Cl)n2)CC1,,CCOC(C)=O,CN(C)C=O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20060111375A1,C1CCNCC1.COc1cc2c(Oc3cc4ccccc4nc3C)ccnc2cc1OCCCl>>COc1cc2c(Oc3cc4ccccc4nc3C)ccnc2cc1OCCN1CCCCC1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US04980363,Cc1nscc1C(=O)Cl.N#CC(N)c1ccco1>>Cc1nscc1C(=O)NC(C#N)c1ccco1,,c1ccncc1,,Cl,,test
US05998436,CC(C)(C)N.O=C1c2ccccc2C(=O)N1c1c(F)c(F)nc(F)c1Cl>>CC(C)(C)Nc1nc(F)c(Cl)c(N2C(=O)c3ccccc3C2=O)c1F,,CC#N,,,,test
US20140206681A1,CCOC(=O)CCCc1ccc(C(=O)OC)cn1>>CCOC(=O)CCCC1CCC(C(=O)OC)CN1,,CC(=O)O,,,,test
US20070167452A1,CC(C)(C)[Si](C)(C)OC[C@@H]1CC[C@H](CNC(=O)c2ccc(OCc3ccccc3)cc2)CC1>>O=C(NC[C@@H]1CC[C@H](CO)CC1)c1ccc(OCc2ccccc2)cc1,,CCOC(C)=O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100010014A1,CC(C)(C#N)NCCNC(=O)OC(C)(C)C.O=C=NS(=O)(=O)Cl>>CC1(C)C(=O)NC(=O)N1CCN,,CO,ClCCl,O,,test
US20160251339A1,C=O.COc1ccc(S(=O)(=O)n2ccc3cc(Cl)ccc32)cc1N1CCNCC1>>COc1ccc(S(=O)(=O)n2ccc3cc(Cl)ccc32)cc1N1CCN(C)CC1,,CO,,[BH3-]C#N.[Na+],,test
US20110275611A1,CC1CC(C(=O)O)CN1C(=O)OC(C)(C)C.NCc1ccccc1>>CC1CC(C(=O)NCc2ccccc2)CN1C(=O)OC(C)(C)C,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140005222A1,COC(=O)c1ccc(C)c(NC(=O)c2cc(N3CCCC(CO)C3)ccc2F)c1C>>Cc1ccc(C(=O)O)c(C)c1NC(=O)c1cc(N2CCCC(CO)C2)ccc1F,,C1CCOC1,O,CCO,[Na+].[OH-],test
US20110288091A1,CCOC(=O)c1cnc2ccc(Cl)cc2c1Nc1ccc(Cc2ccccc2)cc1>>OCc1cnc2ccc(Cl)cc2c1Nc1ccc(Cc2ccccc2)cc1,,C1CCOC1,CCO,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20160007602A1,CCOC(COC(CCO)C(Cc1ccc(F)cc1)C(C)OCc1ccc(OC)cc1)OCC.CI>>CCOC(CO[C@H](CCOC)[C@@H](Cc1ccc(F)cc1)[C@H](C)OCc1ccc(OC)cc1)OCC,,C1CCOC1,,[H-].[Na+],,test
US06248739B1,O=C(NCc1ccc(Cl)cc1)c1cnc2ccc(CN3CCOCC3)cc2c1O.O=C(OCCC(Cl)OC(Cl)CCOC(=O)c1ccccc1)c1ccccc1>>O=C(OCCOCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCOCC3)ccc21)c1ccccc1,,CN(C)C=O,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160237090A1,COC(=O)c1cnn(-c2cnn3c2CN(C(=O)Nc2cc(F)c(F)c(F)c2)[C@@H](C)C3)c1>>C[C@H]1Cn2ncc(-n3cc(CO)cn3)c2CN1C(=O)Nc1cc(F)c(F)c(F)c1,O,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US05340834,O=C(O)CC(O)(CC(=O)O)C(=O)O.[Cr]>>O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Cr+3],,O,,,,test
US20110034507A1,CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CO.O=C1CCc2ccc(O)cc21>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2c(c1)C(=O)CC2,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150018547A1,CCOC(=O)Cc1csc2cc(O)ccc12.Cn1nc(C(F)(F)F)cc1CO>>CCOC(=O)Cc1csc2cc(OCc3cc(C(F)(F)F)nn3C)ccc12,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US03969463,Cc1ccc2c(Cl)c(C)ccc2n1>>Cc1ccc2c(c1Cl)CCC(C)N2,[Pt],,,,,test
US04517202,CC(=O)OC(C)=O.COC1=CCC2C(O)CCC2C1>>COC1=CCC2C(CCC2OC(C)=O)C1,,c1ccncc1,,,,test
US20030109539A1,O=Cc1ccccc1Br.OB(O)c1cccs1>>O=Cc1ccccc1-c1cccs1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US05298520,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCCc1c[nH]c2ccc(Cc3nnn[nH]3)cc12>>CC(C)(C)OC(=O)NCCc1c[nH]c2ccc(Cc3nnn[nH]3)cc12,,ClCCl,,CCN(CC)CC,,test
US20120065200A1,COc1ncnc2c(Br)csc12.OB(O)C1CC1>>COc1ncnc2c(C3CC3)csc12,,O,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20040186301A1,CC(C)(C)OC(=O)CBr.CCOC(=O)CC(=O)OCC>>CCOC(=O)C(CC(=O)OC(C)(C)C)C(=O)OCC,,C1CCOC1,,CCOC(C)=O,[H-].[Na+],test
US20050272743A1,O=[N+]([O-])O.OCCCCBr>>O=[N+]([O-])OCCCCBr,,ClCCl,,O,O=S(=O)(O)O,test
US20090298905A1,COc1cc(N)cc(OC)c1.COc1cc(OC)cc(C(=O)CBr)c1>>COc1cc(OC)cc(-c2cc3c(OC)cc(OC)cc3[nH]2)c1,,CCOC(C)=O,,CN(C)c1ccccc1,,test
US08080566B1,Cl.O=C(OCc1ccccc1)N1CCCC(c2ncc[nH]2)C1>>Cl.c1c[nH]c(C2CCCNC2)n1,,C1COCCO1,,CO,ClCCl,test
US04020076,CCOC(=O)N=C=S.Cc1ccc(CO)cc1>>CCOC(=O)NC(=S)OCc1ccc(C)cc1,,C1CCOC1,CCN(CC)CC,,,test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(c2cc(=O)n3nc4nc(C(F)(F)F)ccc4c3[nH]2)CC1.CO.Cl>>Cc1cc(C(F)(F)F)nc2nn3c(C4CCNCC4)cc(=O)[nH]c3c12.Cl,,C1COCCO1,,,,test
US05491167,Cc1ccccc1OC(C)C(=O)O[C@H]1C[C@H](O[Si](C)(C)C(C)(C)C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O[Si](C)(C)C(C)(C)C)CC(=O)O3)[C@H]21>>Cc1ccccc1OC(C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130053386A1,CCn1nc(-c2cccc(C(C)(C)NS(=O)(=O)CC(F)(F)F)c2)cc1Oc1ccc(C(C)O)cc1>>CCn1nc(-c2cccc(C(C)(C)NS(=O)(=O)CC(F)(F)F)c2)cc1Oc1ccc(C(C)=O)cc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20050187266A1,CCOC(=O)C1(Oc2cccc(CNC(=O)OCCc3cccc(C(F)(F)F)c3)c2)CCC1>>O=C(NCc1cccc(OC2(C(=O)O)CCC2)c1)OCCc1cccc(C(F)(F)F)c1,,C1CCOC1,CO,O,[Li+].[OH-],test
US20090197935A1,CC(=O)Cl.COc1cccc(C(=O)Nc2ccc(OCCN)c(-c3ccnn3C)c2)c1>>COc1cccc(C(=O)Nc2ccc(OCCNC(C)=O)c(-c3ccnn3C)c2)c1,,ClCCl,,CCN(CC)CC,Cl,test
US20080274075A1,CC(C)(C)OC(=O)N1CCNCC1.O=C(CCl)OC(=O)CCl>>CC(C)(C)OC(=O)N1CCN(C(=O)CCl)CC1,,ClCCl,O,CCN(C(C)C)C(C)C,Cl,test
US20060074119A1,COc1ccc([N+](=O)[O-])cc1OC(=O)C(C)(C)C>>COc1ccc(N)cc1OC(=O)C(C)(C)C,[Pd],CCOC(C)=O,,[H][H],,test
US20150266881A1,Cl.N[C@@H]1C[C@H]1c1cccc(C(=O)NC2CC(F)(F)C2)c1.O=C1CCC(F)(F)CC1>>Cl.O=C(NC1CC(F)(F)C1)c1cccc([C@@H]2C[C@H]2NC2CCC(F)(F)CC2)c1,,CC(=O)O,CO,O=C([O-])O.[Na+],,test
US20150038438A1,COc1ccc(Cn2c3c(c(O)c(C(=O)O)c2=O)Cc2cc4c(cc2-3)cc(CO)n4C)c(OC)c1>>COc1ccc(Cn2c3c(c(O)c(C(=O)O)c2=O)Cc2cc4c(cc2-3)cc(C=O)n4C)c(OC)c1,O=[Mn]=O,ClCCl,,,,test
US20160095858A1,NS(=O)(=O)c1cccc([N+](=O)[O-])n1.O=C(O)c1ncc(Cl)nc1Cl>>O=C(NS(=O)(=O)c1cccc([N+](=O)[O-])n1)c1ncc(Cl)nc1Cl,CN(C)C=O,ClCCl,,CCN(CC)CC,O=S(Cl)Cl,test
US20120149711A1,C[C@H]1CC[C@@H](CN)N(C(=O)OC(C)(C)C)C1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>C[C@H]1CC[C@@H](CNC(=O)C(F)(F)F)NC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150299192A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Ic1cccc(CNCc2ccccc2)c1>>CC(C)(C)OC(=O)N(Cc1ccccc1)Cc1cccc(I)c1,CN(C)c1ccncc1,ClCCl,,,,test
US20090291941A1,CS(=O)(=O)Nc1ccc2ccc3ncc(Cl)cc3c(=O)c2c1.OB(O)c1ccccc1>>CS(=O)(=O)Nc1ccc2ccc3ncc(-c4ccccc4)cc3c(=O)c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20060166997A1,COC(=O)C1CCN(C(=O)OC(C)(C)C)C1c1cc(N)ccc1S(=O)(=O)C(C)C.Cl>>COC(=O)C1CCNC1c1cc(N)ccc1S(=O)(=O)C(C)C.Cl,,C1COCCO1,,,,test
US20120083475A1,CC1(C)OC(=O)C2(CC2)C(=O)O1.Nc1cccc(F)c1>>O=C(O)C1CCN(c2cccc(F)c2)C1=O,,CCO,,,,test
US04826837,CNc1ccccn1.O=C(O)c1nnc2ccccc2c1O>>CN(C(=O)c1nnc2ccccc2c1O)c1ccccn1,,ClCCl,,CCN(CC)CC,CCOC(=O)Cl,test
US20160002180A1,ICI.O=C(NC(=S)Nc1cc(Cl)cc(Cl)c1)c1ccccc1>>O=C(/N=C1\SCN1c1cc(Cl)cc(Cl)c1)c1ccccc1,,CC(C)=O,,CCN(CC)CC,,test
US04001325,C#CCBr.CCc1cccc(CC)c1N>>C#CCNc1c(CC)cccc1CC,,CCO,,N#N,O=C([O-])[O-].[K+].[K+],test
US20100267666A1,CC(=O)OC(C)=O.COc1cc(-c2cnc3[nH]cc(C(=O)C4(C)CCCN4)c3n2)cc(OC)c1OC>>COc1cc(-c2cnc3[nH]cc(C(=O)C4(C)CCCN4C(C)=O)c3n2)cc(OC)c1OC,,ClCCl,,,,test
US20110319380A1,CCN(CC)S(F)(F)F.O=c1c2ccc(Br)cc2nc2n1CCC(O)CC2>>O=c1c2ccc(Br)cc2nc2n1CCC(F)CC2,,ClCCl,,,,test
US04264599,O=C1NCCN1C1CCNCC1.c1ccc(COc2ncccc2OCC2CO2)cc1>>O=C1NCCN1C1CCN(CC(O)COc2cccnc2OCc2ccccc2)CC1,,CC(C)O,,,,test
US20110082181A1,Br.C[Si](C)(C)C=[N+]=[N-].Cc1noc(-c2ccc(Br)cc2)c1C(=O)Cl>>Cc1noc(-c2ccc(Br)cc2)c1C(=O)CBr,,CC#N,,,,test
US20050176701A1,CC(C)I.CCc1cc(Br)ccc1O>>CCc1cc(Br)ccc1OC(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05486525,[N-]=[N+]=NCc1ccc(CCC(=O)O)o1>>NCc1ccc(CCC(=O)O)o1,[Ni],CCO,,,,test
US05387684,CCCCc1nc(Cl)c(CO)n1Cc1ccc2nn(-c3ccccc3-c3nnn(C(c4ccccc4)(c4ccccc4)c4ccccc4)n3)c(Br)c2c1>>CCCCc1nc(Cl)c(CO)n1Cc1ccc2nn(-c3ccccc3-c3nnn[nH]3)c(Br)c2c1,,CCO,ClCCl,Cl,,test
US05034395,CCOC(C)Oc1ccc(/C=C\COC(C)=O)cc1>>CCOC(C)Oc1ccc(/C=C\CO)cc1,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20070197512A1,O=C1C=CC(=O)O1.c1ccc2c(c1)NCCO2>>O=C(O)/C=C\C(=O)N1CCOc2ccccc21,,Cc1ccccc1,,,,test
US20150141433A1,COC(=O)c1ccc(CN)cn1.O=S(=O)(Cl)c1ccc(F)c(Cl)c1>>COC(=O)c1ccc(CNS(=O)(=O)c2ccc(F)c(Cl)c2)cn1,,ClCCl,O,CCN(CC)CC,Cl,test
US06514968B1,CC(C)(C)OC(=O)N1CCN(CCOc2cccc3c2c2ccccc2n3Cc2ccccc2)CC1>>c1ccc(Cn2c3ccccc3c3c(OCCN4CCNCC4)cccc32)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05622951,COc1ccccc1N1CCN(C2CCC(O)(c3c(C)ccnc3C)CC2)CC1>>COc1ccccc1N1CCN(C2CC=C(c3c(C)ccnc3C)CC2)CC1,,C1CCOC1,,c1c[nH]cn1,,test
US20100216788A1,CC(C)(C)OC(=O)NCCn1ccc2ncnc(Cl)c21.Cc1cc(N)ccc1Oc1cccc(/C=C/C(C)C)c1>>Cc1cc(Nc2ncnc3ccn(CCNC(=O)OC(C)(C)C)c23)ccc1Oc1cccc(/C=C/C(C)C)c1,,CC(C)O,,O=C([O-])O.[Na+],,test
US06326359B1,COCC=O.COC[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(CN)nc32)[C@H](O)[C@@H]1O>>COCCNCc1nc(NCC(c2ccccc2)c2ccccc2)c2ncn([C@@H]3O[C@H](COC)[C@@H](O)[C@H]3O)c2n1,,C1CCOC1,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20050234244A1,COc1ccc(N)cc1F.O=N[O-]>>COc1ccc(NN)cc1F,,Cl,O,Cl[Sn]Cl,,test
US05028608,CC(C)(C)C(=O)Cl.Nc1cc2c(O)nc[nH]c-2n1>>CC(C)(C)C(=O)Nc1cc2c(O)nc[nH]c-2n1,,c1ccncc1,,,,test
US20090143352A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CN(C)C(=O)c1cc(Br)ccc1NC(=O)N1CCOCC1>>CN(C)C(=O)c1cc(B2OC(C)(C)C(C)(C)O2)ccc1NC(=O)N1CCOCC1,,CN(C)C=O,,ClCCl,CC(=O)[O-].[K+],test
US04242507,C=Cc1ccc2nnn(O)c2c1.O=S(=O)(Cl)c1ccc(Cl)cc1>>C=Cc1ccc2nnn(OS(=O)(=O)c3ccc(Cl)cc3)c2c1,,c1ccccc1,,CCN(CC)CC,,test
US20010027196A1,CSc1nc(N)nc(Br)c1C#N.OCc1ccccc1>>CSc1nc(N)nc(OCc2ccccc2)c1C#N,,COCCOC,,C1CCC2=NCCCN2CC1,,test
US20100105674A1,COc1ccccc1N.Clc1ncc(Br)c(Cl)n1>>COc1ccccc1Nc1nc(Cl)ncc1Br,,CCCCO,,CCN(C(C)C)C(C)C,O,test
US20140057926A1,CS(=O)(=NC(=O)C(F)(F)F)c1ccc(CN2C(=O)c3ccccc3C2=O)cc1>>CS(=N)(=O)c1ccc(CN2C(=O)c3ccccc3C2=O)cc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20120149663A1,COc1ccc(/C=C/c2cc(OC)cc(B3OC(C)(C)C(C)(C)O3)c2)cc1>>COc1ccc(/C=C/c2cc(OC)cc(B(O)O)c2)cc1,,CO,,,,test
US20070032486A1,BrCCBr.COC(=O)c1ccc(OC)c(O)c1O>>COC(=O)c1ccc(OC)c2c1OCCO2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090227566A1,CC(C)(C)OC(=O)N1CCC(Oc2cc(N3CCOCC3)ccc2C(=O)Nc2ccccc2C(=O)Nc2ccc(Cl)cn2)CC1>>O=C(Nc1ccc(Cl)cn1)c1ccccc1NC(=O)c1ccc(N2CCOCC2)cc1OC1CCNCC1,,O=C(O)C(F)(F)F,,,,test
US20030036655A1,CC(C)NC(=O)N1CCC(Cc2ccc(N)cc2)CC1.ClC1=NCCN1>>CC(C)NC(=O)N1CCC(Cc2ccc(NC3=NCCN3)cc2)CC1,,CC(C)O,,O=S(=O)(O)O,,test
US20090181971A1,CCOC(=O)CCCCCCOc1ccc(-c2ccccc2)cc1>>O=C(O)CCCCCCOc1ccc(-c2ccccc2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20130203702A1,BrP(Br)Br.OCc1cncc(Br)c1>>BrCc1cncc(Br)c1,,ClCCl,,CCN(CC)CC,,test
US20070254915A1,CCOC(=O)Cn1ncc2c(=O)[nH]c3ccc(C)cc3c21.CI>>CCOC(=O)Cn1ncc2c(=O)n(C)c3ccc(C)cc3c21,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140243361A1,Cc1cc(Nc2ncnc3ccc(NC(=S)NC(C)(C)CO)cc23)ccc1Oc1ccn2ncnc2c1>>Cc1cc(Nc2ncnc3ccc(NC4=NC(C)(C)CO4)cc23)ccc1Oc1ccn2ncnc2c1,,C1CCOC1,,O,,test
US20030069430A1,CCOC(=O)Cc1ncccc1N>>O=C1Cc2ncccc2N1,,CCOCC,,Cl,,test
US20110021846A1,CCCC[n+]1ccn(C)c1.F[B-](F)(F)F>>CCCC[n+]1ccn(C)c1.F[B-](F)(F)F,,ClCCl,,[Cl-].[Na+],,test
US06191284B1,O=C(Cl)c1ccccc1Br.[Fe+2].c1cc[cH-]c1.c1cc[cH-]c1>>O=C(c1ccccc1Br)[c-]1cccc1.[Fe+2].c1cc[cH-]c1,,ClCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20110144334A1,CC(=O)Cl.Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(=O)Nn1cccn1>>CC(=O)N(C(=O)c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1C)n1cccn1,,C1CCOC1,,[H][H],[H-].[Na+],test
US06136823,NCCO.Nc1cc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Cl)c32)c(F)cc1F>>Nc1cc(-n2cc(C(=O)O)c(=O)c3cc(F)c(NCCO)c(Cl)c32)c(F)cc1F,,c1ccncc1,,CCN(CC)CC,,test
US05521173,C=CCOc1ccc(-c2ccc(C(=O)Cl)cc2)cc1.c1ccc2c(c1)Cn1cccc1CN2>>C=CCOc1ccc(-c2ccc(C(=O)N3Cc4cccn4Cc4ccccc43)cc2)cc1,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,,test
US20120053166A1,C1COCCN1.Cc1ccc(S(=O)(=O)n2ncc3c(-c4nnc(CCl)o4)cc(-c4cnc(Cl)c(NS(C)(=O)=O)c4)cc32)cc1>>CS(=O)(=O)Nc1cc(-c2cc(-c3nnc(CN4CCOCC4)o3)c3cn[nH]c3c2)cnc1Cl,,CC(C)O,,[Na+].[OH-],,test
US20130344030A1,CC(OS(=O)(=O)C(F)(F)F)C1(C(=O)OCc2ccccc2)CCCOC1>>C=CC1(C(=O)OCc2ccccc2)CCCOC1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20090118257A1,Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)O)O2.NCCCn1ccnc1>>Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)NCCCn1ccnc1)O2,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20160102059A1,COc1c(NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)cc(C(C)(C)C)cc1NS(C)(=O)=O.COc1cc(N)ccc1S(N)(=O)=O>>COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)cc(NS(C)(=O)=O)c4OC)c4ccccc34)n2)ccc1S(N)(=O)=O,,C1COCCO1,,CN(C)C=O,,test
US07091199B1,BrCCOc1cccc(-c2noc3ccsc23)c1.NCc1ccc(F)cc1F>>Fc1ccc(CNCCOc2cccc(-c3noc4ccsc34)c2)c(F)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120252777A1,COC(=O)c1ccc(/C=C(\F)c2cccc(-c3nc(Nc4ccc(OC)c(OC)c4)c4ncsc4n3)c2)cc1>>COc1ccc(Nc2nc(-c3cccc(/C(F)=C/c4ccc(C(=O)O)cc4)c3)nc3scnc23)cc1OC,,C1COCCO1,O,Cl,[Na+].[OH-],test
US20090137561A1,CC1(C)CCCCC1=O.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC1(C)CCCC=C1OS(=O)(=O)C(F)(F)F,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20040152750A1,COC(=O)c1ccc(NCc2ccccc2C2CCCCC2)cc1.O=C=Nc1cc(Cl)cc(Cl)c1>>COC(=O)c1ccc(N(Cc2ccc(C3CCCCC3)cc2)C(=O)Nc2cc(Cl)cc(Cl)c2)cc1,,CC#N,,,,test
US07297708B2,CC(Br)C(=O)c1ccc(Cl)cc1Cl.N=C(N)C1(c2ccc(Cl)cc2Cl)CC1>>Cc1[nH]c(C2(c3ccc(Cl)cc3Cl)CC2)nc1-c1ccc(Cl)cc1Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20150164074A1,C=C(F)[Sn](CCCC)(CCCC)CCCC.COC(=O)c1nc(Cl)cc(NC(C)=O)c1Cl>>C=C(F)c1cc(NC(C)=O)c(Cl)c(C(=O)OC)n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,ClCCCl,,,,test
US20110212026A1,O=C(O)c1cccnc1O>>O=c1[nH]cccc1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20050137212A1,CC(=O)c1ccc(Br)cc1.O=C(C1CC1)n1nnc2ccccc21>>O=C(CC(=O)C1CC1)c1ccc(Br)cc1,,C1CCOC1,,O,CC(C)[N-]C(C)C.[Li+],test
US20110118245A1,CCOc1cc2c(Cl)ncnc2cc1OC.Nc1cccc(S)c1>>CCOc1cc2c(Sc3cccc(N)c3)ncnc2cc1OC,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090275606A1,O=C(OCc1ccccc1)C1CCCN1S(=O)(=O)Nc1c(Nc2ccc(Br)cc2F)c(F)c(=O)n2c1CCC2>>O=C(O)C1CCCN1S(=O)(=O)Nc1c(Nc2ccc(Br)cc2F)c(F)c(=O)n2c1CCC2,,C1CCOC1,CO,[Li+].[OH-],,test
US20030166639A1,C=Cc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3cc(C)nc(C)c3)c2)cc1C(F)(F)F>>C=Cc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3cc(C)nc(C)c3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090137595A1,Cc1cc(C(=O)Cl)n(C)n1.Nc1ccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)cc1>>Cc1cc(C(=O)Nc2ccc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)cc2)n(C)n1,,C1CCOC1,,CCN(CC)CC,,test
US04103085,CCOC(=O)CCl.O=c1[nH]nc2ccc(Cl)nn12>>CCOC(=O)Cn1nc2ccc(Cl)nn2c1=O,,CN(C)C=O,,O,[H-].[Na+],test
US20040242410A1,CC1=C(C)C(c2ccccc2C=O)C(C)=C1C.Cc1cc(C)c(N)c(C)c1>>CC1=C(C)C(c2ccccc2C=Nc2c(C)cc(C)cc2C)C(C)=C1C,,CCO,,CC(=O)O,,test
US20110166351A1,CCN(CC1CCCC1)c1ccc(OC)nc1CNc1ncc(OCCSC)cn1.N#Cc1cc(CBr)cc(C(F)(F)F)c1>>CCN(CC1CCCC1)c1ccc(OC)nc1CN(Cc1cc(C#N)cc(C(F)(F)F)c1)c1ncc(OCCSC)cn1,,CN(C)C=O,,O,[H-].[Na+],test
US20160264547A1,CNC(C)C(OC)OC.O=C(Nc1cc(C(F)(F)F)ccn1)Oc1ccccc1>>CC1C(O)N(c2cc(C(F)(F)F)ccn2)C(=O)N1C,,C1COCCO1,O,CCOC(C)=O,Cl,test
US20120149662A1,CC(C)(C)C(=O)OCn1ccc2c(-c3cnn([C@H](CCO)C4CCCC4)c3)cnnc21>>OCC[C@H](C1CCCC1)n1cc(-c2cnnc3[nH]ccc23)cn1,,CO,,[Na+].[OH-],,test
US08318928B2,CC(C)(C)COc1c(/C=C/c2nc3sccn3c2C(=O)O)cccc1OC(F)F.Nc1nc(C2CCC2)cs1>>CC(C)(C)COc1c(/C=C/c2nc3sccn3c2C(=O)Nc2nc(C3CCC3)cs2)cccc1OC(F)F,CN(C)c1ccncc1,C1CCOC1,CN(C)C=O,CCN=C=NCCCN(C)C,Cl,test
US20020169171A1,C(=NNc1ccccc1)c1ccccc1.CCOC=C(C#N)C(=O)OCC[Si](C)(C)C>>C[Si](C)(C)CCOC(=O)C(C#N)=CN(N=Cc1ccccc1)c1ccccc1,,CCCCCC,,,,test
US20100184815A1,CC(C)(C)OC(=O)C(C)(C)Sc1ccc(C(=O)O)cc1.Cc1ccc(Cn2cc([C@@H](C)O)nn2)cc1>>COC(=O)C(C)(C)Sc1ccc(C(=O)O[C@H](C)c2cn(Cc3ccc(C)cc3)nn2)cc1,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,,,test
US20150087626A1,O=C(OCc1cccc(C(F)(F)F)c1)[C@H]1C[C@@H](O)CN1Cc1cccc(C(F)(F)F)c1>>O=C1C[C@H](C(=O)OCc2cccc(C(F)(F)F)c2)N(Cc2cccc(C(F)(F)F)c2)C1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20120202785A1,Nc1ccccc1.O=[N+]([O-])c1ccc(F)c(Cl)c1F>>O=[N+]([O-])c1ccc(F)c(Cl)c1Nc1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US06498165B1,C[C@H](Nc1nccc(-n2cnc3cc(-c4ccc(Cl)nn4)ccc32)n1)c1ccccc1>>C[C@H](Nc1nccc(-n2cnc3cc(-c4cccnn4)ccc32)n1)c1ccccc1,[Pd],C1CCOC1,CCO,[H][H],,test
US20150353493A1,BrCc1ccccc1.COc1ccc2c(c1)CCC(Cc1ccncc1Br)C2=O>>COc1ccc2c(c1)CCC(Cc1cc[n+](Cc3ccccc3)cc1Br)C2=O.[Br-],,ClCCl,,,,test
US20030109563A1,CS(=O)(=O)Cl.O=C1COC(SCCC(F)=C(F)F)N1>>CS(=O)(=O)Oc1coc(SCCC(F)=C(F)F)n1,,C1CCOC1,,CCN(CC)CC,,test
US20090186881A1,COC(=O)[C@@H](Cc1cc(C)c(OCc2ccccc2)c(C)c1)OC(=O)N1CCC(c2cc3ccccc3[nH]c2=O)CC1>>Cc1cc(C[C@@H](OC(=O)N2CCC(c3cc4ccccc4[nH]c3=O)CC2)C(=O)O)cc(C)c1OCc1ccccc1,,C1CCOC1,O,[Li+].[OH-],,test
US20090076046A1,CCn1nc(N)cc1C(=O)OC.O=Cc1ccc(F)cc1>>CCn1nc(NCc2ccc(F)cc2)cc1C(=O)OC,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20020156296A1,CC(=O)Oc1c(C(C)(C)C)cc2c(c1C)CC(C)(C)O2>>Cc1c(O)c(C(C)(C)C)cc2c1CC(C)(C)O2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100267712A1,Cn1ccc2cc(N3Cc4ccc(O)cc4C3=O)ccc21.FC(F)(F)CI>>Cn1ccc2cc(N3Cc4ccc(OCC(F)(F)F)cc4C3=O)ccc21,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05892133,CC1CCC2C(CC(=O)OC2(C)C)C1>>CC1CCC(C(C)(C)O)C(CCO)C1,,CCOCC,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20160237091A1,C=C(c1ccccc1)c1cc2cc3c(-c4ccnc(C)c4)nn(C(c4ccccc4)(c4ccccc4)c4ccccc4)c3cc2[nH]c1=O.OO>>Cc1cc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3cc4[nH]c(=O)c(C(CO)c5ccccc5)cc4cc23)ccn1,,C1CCOC1,,O,[Na+].[OH-],test
US04113940,CC1C=C(C(=O)OCC(Cl)(Cl)Cl)N2C(=O)C(NC(=O)CN(C(=O)OC(C)C3CC3)c3ccccc3)[C@H]2S1>>CC1C=C(C(=O)O)N2C(=O)C(NC(=O)CN(C(=O)OC(C)C3CC3)c3ccccc3)[C@H]2S1,[Zn],CC(=O)O,,,,test
US20060173034A1,COc1cc2c(Nc3cccc(CO)c3C)c(C(N)=O)cnc2cc1O.ClCCCCBr>>COc1cc2c(Nc3cccc(CO)c3C)c(C(N)=O)cnc2cc1OCCCCl,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110230536A1,Cc1cc(C(F)(F)F)nn1-c1ccc(C(=O)Nc2ccc(Cl)cc2)cc1[N+](=O)[O-]>>Cc1cc(C(F)(F)F)nn1-c1ccc(C(=O)Nc2ccc(Cl)cc2)cc1N,,CCO,,Cl,,test
US04595690,COC(=O)CNc1ccc(CCOC(=O)C2=C(C)NC(C)=C(C(=O)OC)C2c2cccc([N+](=O)[O-])c2)cc1>>COC(=O)CNc1ccc(CCOC(=O)C2=C(C)NC(C)=C(C(=O)OC)C2c2cccc([N+](=O)[O-])c2)cc1,,O,,Cl,[NH4+].[OH-],test
US20020052399A1,O=S(=O)(Cl)Cl.c1ccc2c(c1)OCO2>>O=S(=O)(Cl)c1ccc2c(c1)OCO2,,CN(C)C=O,,,,test
US20110288063A1,CCOC(=O)C(O)=C1C(=O)C2CCC1C2.NN>>CCOC(=O)c1n[nH]c2c1C1CCC2C1,,CC(=O)O,,ClCCl,O,test
US20060160864A1,CCCCOCCOc1ccc(-c2ccc(N3CCCCC3C)c(/C=C/C(=O)OCC)c2)cc1>>CCCCOCCOc1ccc(-c2ccc(N3CCCCC3C)c(/C=C/C(=O)O)c2)cc1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US05624950,CC1(C)C=CC(=O)C=C1.CCCCOCN(Cc1ccccc1)C[Si](C)(C)C>>CC1(C)C=CC(=O)C2CN(Cc3ccccc3)CC21,O=C(O)C(F)(F)F,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US04442108,CCOc1ccc(CC(=O)NCCc2ccc(OC(C)C)c(OC(C)C)c2)cc1OCC.O=P(Cl)(Cl)Cl>>CCOc1ccc(CC2=NCCc3cc(OC(C)C)c(OC(C)C)cc32)cc1OCC.Cl,,c1ccccc1,,,,test
US05932582,Cc1cc(OCC(=O)N(C)C)ccc1NC(=O)OC(C)(C)C>>Cc1cc(OCC(=O)N(C)C)ccc1N,,O=C(O)C(F)(F)F,,,,test
US20040067999A1,CC(=O)N1CCC(C(=O)O)CC1.Cc1cc2c(c(C)c1NC(=O)N1CCCC(C(N)=O)C1)c1ccccc1n2C(C)C>>CC(=O)N1CCC(C(=O)Nc2c(C)cc3c(c2C)c2ccccc2n3C(C)C)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20110046128A1,COP(=O)(O)C(C)(C)C(=O)[O-].COc1ccc2cc(C(C)=O)ccc2c1>>COC(=O)C=C(C)c1ccc2cc(OC)ccc2c1,,[Cl-],[NH4+],C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20130338367A1,CSCCC(=O)Nc1cn(-c2cccnc2)nc1Cl>>CSCCCNc1cn(-c2cccnc2)nc1Cl,,C1CCOC1,,O,,test
US20160115119A1,N[C@@H]1CCc2c(F)cc(F)cc21.O=C(O)c1ccccc1[N+](=O)[O-].O=Cc1ccccc1.[C-]#[N+]C1=CCC(c2ccccc2)CC1>>NC(=O)[C@@H](c1ccccc1)N(C(=O)c1ccccc1[N+](=O)[O-])[C@@H]1CCc2c(F)cc(F)cc21,,CCN(CC)CC,,CO,Cl,test
US20030125383A1,CC1(C)CCC(C)(C)c2cc(N)ccc21.O=C(Cl)Cc1ccccc1>>CC1(C)CCC(C)(C)c2cc(NC(=O)Cc3ccccc3)ccc21,,ClCCl,,CCN(CC)CC,,test
US20160096827A1,C[C@@H]1C[C@@H](Oc2ccc(-c3ncnc(Nc4ccc(N5CCN(C6COC6)CC5)cc4)n3)cc2C#N)CCN1C(=O)OC(C)(C)C>>C[C@@H]1C[C@@H](Oc2ccc(-c3ncnc(Nc4ccc(N5CCN(C6COC6)CC5)cc4)n3)cc2C#N)CCN1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100069394A1,C[C@H]1CNC[C@@H](C)N1.FC(F)(F)c1nnc(Cl)cc1-c1ccccc1>>C[C@H]1CN(c2cc(-c3ccccc3)c(C(F)(F)F)nn2)C[C@@H](C)N1,,CC#N,CCOCC,CCN(C(C)C)C(C)C,Cl,test
US20130090328A1,Cc1cc2nc(N3CCS(=O)c4ccccc4C3)nc(N[C@@H]3CN(C(=O)OCc4ccccc4)C[C@H]3F)c2s1>>Cc1cc2nc(N3CCS(=O)c4ccccc4C3)nc(N[C@@H]3CNC[C@H]3F)c2s1,,CO,,[K+].[OH-],,test
US05661162,CC(C)(C)OC(=O)N1CCC(CSCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)CC1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)OC(=O)N1CCC(CS(=O)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)CC1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20150011461A1,CC1(C)CC(C(=O)O)N(C(=O)CCN2C(=O)c3ccccc3C2=O)C1.COC(=O)C#CC(=O)OC>>COC(=O)c1c(C(=O)OC)c2n(c1CCN1C(=O)c3ccccc3C1=O)CC(C)(C)C2,,CC(=O)OC(C)=O,,,,test
US20070265326A1,BrCc1ccccc1.Cc1cc(Br)c(C=NNc2cccc(C(=O)O)c2)c(Br)c1>>Cc1cc(Br)c(C=NNc2cccc(C(=O)OCc3ccccc3)c2)c(Br)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110207716A1,CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3Br)nc2N1C1CCCC1.O=C1NCCO1>>CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3N3CCOC3=O)nc2N1C1CCCC1,[Cu]I,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=C([O-])[O-].[K+].[K+],test
US20090197863A1,CCCCC=O.NC(=O)c1cccc2nc(C3CCN(C(=O)OCc4ccccc4)CC3)oc12>>CCCCCN1CCC(c2nc3cccc(C(N)=O)c3o2)CC1,[Pd],CO,,[H][H],,test
US05962436,CC(=O)c1ccc2ccccc2c1.COC(=O)Cc1ccccc1CON>>COC(=O)Cc1ccccc1CON=C(C)c1ccc2ccccc2c1,,c1ccncc1,,Cl,,test
US20080045528A1,CNC(=O)c1cc(Cl)ccn1.CSc1nc2ccc(O)cc2o1>>CNC(=O)c1cc(Oc2ccc3nc(SC)oc3c2)ccn1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20080070919A1,C1=CC[C@H]2CN[C@@H](C1)CN2c1ccc2ccccc2c1.c1ccc2c(c1)[nH]c1cccc(OC[C@@H]3CO3)c12>>O[C@H](COc1cccc2[nH]c3ccccc3c12)CN1CC2CC=CCC1CN2c1ccc2ccccc2c1,,CCO,,CCN(C(C)C)C(C)C,,test
US05925253,C=CCCOC(=O)C(=C)C.O=C(OO)c1cccc(Cl)c1>>C=C(C)C(=O)OCCC1CO1,,ClCCl,,,,test
US04863920,CC(O)C#Cc1ncn2c1CN(C)C(=O)c1c(Cl)cccc1-2.CI>>COC(C)C#Cc1ncn2c1CN(C)C(=O)c1c(Cl)cccc1-2,,CN(C)C=O,,[K+].[OH-],,test
US05021413,C1CCN(CC2COCCN2)C1.O=C1CC(C(=O)Cl)c2ccccc21>>Cl.O=C1CC(C(=O)N2CCOCC2CN2CCCC2)c2ccccc21,,CCN(CC)CC,,,,test
US05047411,CNC(=S)Nc1ccc(CCc2ccccn2)cc1>>CNc1nc2ccc(CCc3ccccn3)cc2s1,,ClC(Cl)Cl,,BrBr,,test
US04996218,BrCCCCCCBr.OCCc1nc2ccccc2o1>>BrCCCCCCOCCc1nc2ccccc2o1,,O,,ClCCl,[Na+].[OH-],test
US20060052315A1,Nc1ccc(I)cc1.OB(O)c1ccccc1C(F)(F)F>>Nc1ccc(-c2ccccc2C(F)(F)F)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20060052371A1,CC(=O)Oc1ccc(C#N)cc1.COC(=O)c1ccccc1S>>O=c1nc(-c2ccc(O)cc2)sc2ccccc12,,Cc1ccccc1,,CCN(CC)CC,,test
US05240957,CCN1CCC[C@H]1CNC(=O)c1c(OCc2ccccc2)ccc(OCc2ccccc2)c1OC>>CCN1CCC[C@H]1CNC(=O)c1c(O)ccc(O)c1OC,[Pd],CCO,CCOCC,Cl,[H][H],test
US04614718,CCCCCCCC/C=C\CCCCCCCC(=O)O.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>CCCCCCCC/C=C\CCCCCCCC(=O)O.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO,,O=P([O-])([O-])[O-],,,,test
US05356898,COCCOCOc1c(C(C)(C)C)nc(C(=O)NN)nc1C(C)(C)C.S=C=S>>CC(C)(C)c1nc(-c2n[nH]c(=S)o2)nc(C(C)(C)C)c1O,,CO,,[K+].[OH-],,test
US20040198825A1,CCCOc1cc2c(cc1/C(=C/C=C/C(C)=C/C(=O)OCC)C(F)(F)F)C(C)(C)CCC2(C)C>>CCCOc1cc2c(cc1/C(=C/C=C/C(C)=C/C(=O)O)C(F)(F)F)C(C)(C)CCC2(C)C,,CCCCCC,CCOC(C)=O,CCO,[Na+].[OH-],test
US20070054903A1,CC1(C)OB(c2ccc3cc(NC(=O)c4ccsc4)ccc3c2)OC1(C)C.Cc1n[nH]c2ccc(Br)cc12>>Cc1n[nH]c2ccc(-c3ccc4cc(NC(=O)c5ccsc5)ccc4c3)cc12,[Pd],O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20130137679A1,BrCCCCOc1ccc2scnc2c1.Clc1cccc(C2CCNCC2)c1Cl>>Clc1cccc(C2CCN(CCCOc3ccc4scnc4c3)CC2)c1Cl,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US20150232481A1,C=CCBr.C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(Cn4cc(CO)nn4)nn23)CC1>>C=CCOCc1cn(Cc2cc3nc(C)c([C@H](OC(C)(C)C)C(=O)OCC)c(N4CCC(C)(OCC=C)CC4)n3n2)nn1,,CN(C)C=O,,[H-].[Na+],,test
US20060241147A1,CNC.O=C(CCl)Nc1ccc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)nc1>>CN(C)CC(=O)Nc1ccc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)nc1,,CC#N,CCO,O,O=C([O-])[O-].[K+].[K+],test
US20130023541A1,CC(C)OC(=O)c1cccnc1N1CCN(Cc2ccc(CO)cc2)CC1.CCOc1ccc(O)cc1>>CCOc1ccc(OCc2ccc(CN3CCN(c4ncccc4C(=O)OC(C)C)CC3)cc2)cc1,,C1CCOC1,CS(C)=O,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120225061A1,Fc1cc(F)cc(Br)c1.O=C1COC1>>OC1(c2cc(F)cc(F)c2)COC1,,C1CCOC1,,,,test
US20140371199A1,CCOC(=O)c1ccc(-c2cn3ccnc3cn2)cc1.O=C1CCC(=O)N1I>>CCOC(=O)c1ccc(-c2cn3c(I)cnc3cn2)cc1,,CN(C)C=O,,,,test
US20090318474A1,C1COCCN1.Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)Cl)c3)n2)n1>>Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2cccc(-c3cccc(S(=O)(=O)N4CCOCC4)c3)n2)n1,,C1CCOC1,CCOC(C)=O,,,test
US04126689,CCOC(=O)N1CCC(Nc2c(C)cccc2C)CC1.O=C(Cl)Cc1ccccc1>>CCOC(=O)N1CCC(N(C(=O)Cc2ccccc2)c2c(C)cccc2C)CC1,,c1ccccc1,,c1ccncc1,,test
US20080280911A1,CCCCO.Cc1cc(I)ccc1NN=C(C(=O)Cl)C(=O)Cl>>CCCCOC(=O)c1n[nH]c2c(C)cc(I)cc2c1=O,Cl[Ti](Cl)(Cl)Cl,ClCCCl,,,,test
US20090197864A1,CC1CO1.FC(F)(F)c1cccc(Cl)c1>>CC(O)Cc1c(Cl)cccc1C(F)(F)F,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20140275087A1,CO.Cn1cnc(S(=O)(=O)N2C[C@H](Nc3cc(C(F)(F)F)nc(S(C)(=O)=O)n3)[C@@H](c3ccccc3)C2)c1>>COc1nc(N[C@H]2CN(S(=O)(=O)c3cn(C)cn3)C[C@@H]2c2ccccc2)cc(C(F)(F)F)n1,,CO,,C[O-].[Na+],,test
US06610692B1,CC#CCCN.Clc1ncccn1>>C#CCCCNc1ncccn1,,CCO,,CCN(CC)CC,,test
US20060198785A1,BrCCn1cccn1.NCCN>>NCC=NCCn1cccn1,,C1CCOC1,O,,,test
US06391916B1,COCC(=O)O.OC1C#CCCCCC#C/C1=C\c1cccc2ccccc12>>CC(=O)OC1C#CCCCCC#C/C1=C\c1cccc2ccccc12,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20130267493A1,COc1ccc(-c2cc3c(C(=O)Oc4ccc(C)cc4)n[nH]c3cc2Cl)cc1.NS(=O)(=O)c1ccccc1>>COc1ccc(-c2cc3c(C(=O)NS(=O)(=O)c4ccccc4)n[nH]c3cc2Cl)cc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20080207654A1,CCCc1nc(C)[nH]c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.OCc1ccccn1>>CCCc1nc(C)n(Cc2ccccn2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20070027155A1,C[C@H]1CNCCN1.Clc1cccnc1Cl>>c1ccc(N2CCNCC2)nc1,,CC(=O)N(C)C,O,O=C([O-])[O-].[K+].[K+],,test
US20090253758A1,CC(C)(C)[Si](C)(C)Cl.Cc1c(N[C@@H](C(=O)NNC(=O)c2ccc(C#N)cc2)[C@H](C)O)ccc(C#N)c1C(F)(F)F>>Cc1c(N[C@@H](C(=O)NNC(=O)c2ccc(C#N)cc2)[C@H](C)O[Si](C)(C)C(C)(C)C)ccc(C#N)c1C(F)(F)F,,CN(C)C=O,,c1c[nH]cn1,,test
US20090023964A1,CCc1cc(C)cc(CC)c1N.Cl>>CCc1cc(C)cc(CC)c1Cl,,Clc1ccccc1Cl,,CC(C)CCON=O,,test
US20110076291A1,CC(C)n1ncnc1-c1nc2c(s1)CCOc1ccc(-c3cccn(CC(=O)O)c3=O)cc1-2.[NH4+]>>CC(C)n1ncnc1-c1nc2c(s1)CCOc1ccc(-c3cccn(CC(N)=O)c3=O)cc1-2,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160009744A1,Cc1sc(C2OCCO2)cc1Br.O=Cc1cccc(Cl)c1>>Cc1sc(C2OCCO2)cc1C(O)c1cccc(Cl)c1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20150045378A1,COc1c(O)cccc1CC1C(=O)OC(C)(C)OC1=O>>COc1c(O)cccc1CCC(=O)O,,CN(C)C=O,,CCOC(C)=O,O,test
US20060148811A1,COc1ccc2cc(C(=O)CBr)ccc2c1Cl.Cl.Cl.c1ccc(CN2CCNCC2)cc1>>COc1ccc2cc(C(=O)CN3CCN(Cc4ccccc4)CC3)ccc2c1Cl.Cl.Cl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04410537,CCOC(=O)CCCCOc1cccc(O)c1C=O>>O=Cc1c(O)cccc1OCCCCC(=O)O,,[Na+],[OH-],Cl,,test
US20100173933A1,CC(=S)Nc1ccc(Oc2ccccc2)cc1>>Cc1nc2ccc(Oc3ccccc3)cc2s1,,ClCCl,,BrBr,,test
US05646173,C[C@H](O)CN.O=CCC1CC(=O)c2ccccc2O1>>C[C@H](O)Cn1ccc2c1-c1ccccc1OC2,Cc1ccc(S(=O)(=O)O)cc1,,,Cc1ccccc1,O,test
US20120252777A1,CO[Na].Cc1ccnc(Cl)c1>>COc1cc(C)ccn1,,CS(C)=O,,O,,test
US20050228044A1,CCOC(C)=O.CN(C)C=O.Oc1ccc(SC(F)(F)F)cc1>>C=CCOc1ccc(SC(F)(F)F)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US08138168B1,CC(C)(C)C=O.COCCCN.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>COCCCn1cncc1C(C)(C)C,,ClCCl,,O=S(=O)([O-])[O-].[Mg+2],,test
US20040072871A1,COc1ccc(B(O)O)cc1.O=Cc1cc(Br)cs1>>COc1ccc(-c2csc(C=O)c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,COCCOC,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20040224996A1,CCOC(C)=O.Cc1c(Cl)cccc1S(=O)(=O)Nc1nc(CCNCCO)cs1>>Cc1c(Cl)cccc1S(=O)(=O)Nc1nc(CCN2CCOC2=O)cs1,,C1CCOC1,,CCN(CC)CC,,test
US20110015172A1,O=C(Nc1cc(-c2cn(S(=O)(=O)c3ccccc3)c3nccnc23)cc(Cl)n1)c1ccccc1>>Nc1cc(-c2c[nH]c3nccnc23)cc(Cl)n1,,CCO,,Cl,,test
US04102890,S=C(NCCCl)NC(C1CC1)C1CC1>>C1CSC(NC(C2CC2)C2CC2)=N1,,O,,,,test
US20130267510A1,CC(C)C(=O)OC(=O)C(C)C.COCOc1cccc(OCOC)c1>>COCOc1cccc(OCOC)c1C(=O)C(C)C,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20130310411A1,COC(=O)c1ccc(S)cc1.Clc1c2ccccc2nc2cccc(Br)c12>>COC(=O)c1ccc(Sc2c3ccccc3nc3cccc(Br)c23)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US04455432,COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1.NO>>COc1ccc2c(c1)c(CC(=O)NO)c(C)n2C(=O)c1ccc(Cl)cc1,,ClC(Cl)Cl,O,CCN(CC)CC,CCOC(=O)Cl,test
US20130122506A1,CCCC[Sn](CCCC)(CCCC)c1cccs1.O=[N+]([O-])c1cc(I)cn1[C@H]1C[C@H](O)[C@@H](CO)O1>>O=[N+]([O-])c1cc(-c2cccs2)cn1[C@H]1C[C@H](O)[C@@H](CO)O1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,,,test
US05708174,COC(=O)c1cccc2c1SCCC2O>>COC(=O)c1cccc2c1SCC=C2,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04012407,N#CC=C1OC(=O)c2ccccc21>>N#CC1C(=O)c2ccccc2C1=O,,CO,,[Na],,test
US20150141396A1,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.Oc1cc(Br)cc(Br)c1>>Cn1cc(-c2cc(O)cc(Br)c2)cn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20160272617A1,Cc1cc(C(=O)O)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1.N>>Cc1cc(C(N)=O)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)cc1,,C1CCOC1,CO,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140350019A1,Nc1c(F)ccc(O)c1F.O=C(O)c1cc(F)cc(-c2cccc(F)c2)c1>>O=C(Nc1c(F)ccc(O)c1F)c1cc(F)cc(-c2cccc(F)c2)c1,CN(C)C=O,C1CCOC1,ClCCl,O=C(Cl)C(=O)Cl,O=C([O-])O.[Na+],test
US20160212998A1,Cc1nn(C)c(-c2c(F)cc(OCCC(C)C)cc2F)c1C(=O)c1ccc(F)cc1Cl>>Cc1nn(C)c(-c2c(F)cc(OCCC(C)C)cc2F)c1C(O)c1ccc(F)cc1Cl,,CO,,[BH4-].[Na+],,test
US05623081,CC(C)(C)[Si](OC[C@H]1O[C@H](CN)C[C@@H]1O)(c1ccccc1)c1ccccc1.O=C(Cl)OCc1ccc([N+](=O)[O-])cc1>>CC(C)(C)[Si](OC[C@H]1O[C@H](CNC(=O)OCc2ccc([N+](=O)[O-])cc2)C[C@@H]1O)(c1ccccc1)c1ccccc1,,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20130143907A1,COc1cc(CO)cc(C)n1.O=C1CCC(=O)N1Br>>COc1cc(CO)c(Br)c(C)n1,,CC(=O)O,,[Na+].[OH-],,test
US20150336986A1,COC(=O)CCCBr.Cn1c(=O)c2c(-c3cccc(C#N)c3)[nH]cc2n(C)c1=O>>COC(=O)CCCn1cc2c(c1-c1cccc(C#N)c1)c(=O)n(C)c(=O)n2C,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070185168A1,O=C1CCCc2cc(C(=O)CCl)ccc2N1>>O=C1CCCc2cc(C(O)CCl)ccc2N1,,CCOC(C)=O,,CCN(CC)CC,O=CO,test
US20150266857A1,CC(C)(C)OC(=O)N(Cc1nc2ccc(-c3cn(S(=O)(=O)c4ccccc4)c4cc(F)ccc34)cc2o1)S(C)(=O)=O>>CC(C)(C)OC(=O)N(Cc1nc2ccc(-c3c[nH]c4cc(F)ccc34)cc2o1)S(C)(=O)=O,,CO,O,Cl,[Na+].[OH-],test
US06156758,CC(C)(C)OC(=O)c1ccc(NC2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)cc1>>O=C(O)c1ccc(NC2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)cc1,,Cl,,,,test
US06107342,CCOC(=O)[C@H]1[C@@H]2C[C@@H](OS(=O)(=O)C(F)(F)F)[C@@](N=[N+]=[N-])(C(=O)OCc3ccccc3)[C@H]12>>CCOC(=O)[C@H]1[C@@H]2C=C[C@](N=[N+]=[N-])(C(=O)OCc3ccccc3)[C@H]12,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20060004017A1,COc1cc2c(Oc3ccc(Br)cc3F)ncnc2cc1OCCCN.CS(=O)(=O)Cl>>COc1cc2c(Oc3ccc(Br)cc3F)ncnc2cc1OCCCNS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20080261967A1,COc1ccc(F)cc1C=CC1COCCO1>>COc1ccc(F)cc1CCC1COCCO1,[Pd],CCO,,,,test
US20050165063A1,CCCN(CCC)CCCN.O=C(O)c1ccc(CN(Cc2ncc[nH]2)Cc2ncc[nH]2)cc1>>CCCN(CCC)CCCNC(=O)c1ccc(CN(Cc2ncc[nH]2)Cc2ncc[nH]2)cc1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US05064946,BrBr.[N-]=[N+]=N[C@H]1C[C@H](n2ccc(=O)[nH]c2=O)O[C@@H]1CO>>[N-]=[N+]=N[C@H]1C[C@H](n2cc(Br)c(=O)[nH]c2=O)O[C@@H]1CO,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20060128724A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.COC(=O)C(C)(C)Br>>COC(=O)C(C)(C)n1cc(B2OC(C)(C)C(C)(C)O2)cn1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150299218A1,O=Cc1cccc(Br)c1.OCCc1c[nH]c2ccccc12>>Brc1cccc(C2OCCc3c2[nH]c2ccccc32)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US03934008,COC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCNC(=O)OC(C)(C)C.NC(=O)C[C@H](NC(=O)OCc1ccccc1)C(=O)Oc1ccc([N+](=O)[O-])cc1>>COC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1,,CN(C)C=O,,,,test
US20090012093A1,CC(C)(C)OC(=O)CCc1ccc(OCc2cccc(Br)c2)cc1.O=Cc1ccccc1B(O)O>>CC(C)(C)OC(=O)CCc1ccc(OCc2cccc(-c3ccccc3C=O)c2)cc1,,CCOC(C)=O,Cc1ccccc1,CCO,O=C([O-])[O-].[K+].[K+],test
US20160000760A1,CC(C)(C)N.Cc1ccc(Br)cc1S(=O)(=O)Cl>>Cc1ccc(Br)cc1S(=O)(=O)NC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20140005168A1,Clc1cc2c(cn1)cnn2-c1cccc(N2CCCNCC2)n1.O=C1COC1>>Clc1cc2c(cn1)cnn2-c1cccc(N2CCCN(C3COC3)CC2)n1,,ClCCCl,,,,test
US04273782,O=C(CCCl)Nc1ccccc1.c1ccc2c(Cc3ncc[nH]3)c[nH]c2c1>>O=C(CCn1cc(Cc2ncc[nH]2)c2ccccc21)Nc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20120178765A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cc(O)cc(C(=O)O)c1>>CC(C)(C)OC(=O)Nc1cc(O)cc(C(=O)O)c1,,C1COCCO1,O,Cl,[Na+].[OH-],test
US06013663,CCCCN.CO.O=C1c2ccccc2C(=O)N1CCCCCC1CCSS1>>COC(=O)CNCCCCCC1CCSS1,,Cc1ccccc1,,C1COCCO1,,test
US05006563,CCN(CC)S(F)(F)F.CCOC(=O)C(F)(F)C(O)c1cccc(Cl)c1>>CCOC(=O)C(F)(F)C(F)c1cccc(Cl)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20050288273A1,COC(OC)N(C)C.O=C1CCCCc2cc(N3C[C@H](COc4ccon4)OC3=O)ccc21>>CN(C)C=C1CCCc2cc(N3C[C@H](COc4ccon4)OC3=O)ccc2C1=O,,CCCO,,,,test
US04845107,COc1ccc(N)cn1.O=C(O)C(F)F>>COc1ccc(NC(=O)C(F)F)cn1,,ClCCl,,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US20140100168A1,C#CCBr.Oc1ccccc1>>C#CCOc1ccccc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20070142357A1,C[C@@H]1CN(C(=O)C(F)(F)F)CCc2ccc(Cl)cc21.O=C1CCC(=O)N1Cl>>C[C@@H]1CN(C(=O)C(F)(F)F)CCc2ccc(Cl)c(Cl)c21,,ClCCl,O,O=S(=O)(O)C(F)(F)F,,test
US20070060589A1,CCOC(=O)c1cnc(C)nc1-c1cccc(Br)c1.NN>>Cc1ncc(C(=O)NN)c(-c2cccc(Br)c2)n1,,CCO,,O,,test
US20100267712A1,CC(=O)Cl.Cn1ccc2cc(N3Cc4c(N)cccc4C3=O)ccc21>>CC(=O)Nc1cccc2c1CN(c1ccc3c(ccn3C)c1)C2=O,,C1CCOC1,,CCN(CC)CC,,test
US03998879,CC(C)C1CC(=O)CC(=O)C1.O=C=NS(=O)(=O)c1ccccc1>>CC(C)C1CC(=O)C(C(=O)NS(=O)(=O)c2ccccc2)C(=O)C1,,c1ccccc1,,,,test
US05036067,CC(NO)c1ccc2c(c1)Sc1ccccc1O2.C[Si](C)(C)N=C=O>>CC(c1ccc2c(c1)Sc1ccccc1O2)N(O)C(N)=O,,C1CCOC1,,O,,test
US04433152,Cl.N=C(N)N1CCC(CCC(=O)O)CC1.Oc1ccc(F)cc1>>Cl.N=C(N)N1CCC(CCC(=O)Oc2ccc(F)cc2)CC1,,c1ccncc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20090069370A1,COC(=O)c1ccc(Oc2ccc3c(c2)CCN([C@@H]2CCN(C4CCC4)C2)C3=O)cc1>>O=C(O)c1ccc(Oc2ccc3c(c2)CCN([C@@H]2CCN(C4CCC4)C2)C3=O)cc1,,CO,,,,test
US06387938B1,N#CCC(=O)c1cccc2nc(CCc3ccccc3)[nH]c12>>N#CCC(O)c1cccc2nc(CCc3ccccc3)[nH]c12,,CCO,,[BH4-].[Na+],,test
US20100267696A1,CCOC(=O)c1csc(C2CCCCC2)c1>>O=C(O)c1csc(C2CCCCC2)c1,,O,,[Na+].[OH-],,test
US20120238599A1,C=COCCONC(=O)c1c(Nc2ccc(I)cc2F)n(C)c(=O)c2nc(C)oc12>>Cc1nc2c(=O)n(C)c(Nc3ccc(I)cc3F)c(C(=O)NOCCO)c2o1,,CO,,Cl,,test
US20130059834A1,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](CO)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N[C@@H]1CC[C@H](COS(C)(=O)=O)C1,,ClCCl,,CCN(CC)CC,,test
US20120028924A1,Cc1ccc(S(=O)(=O)Cl)cc1.Clc1ncc(Br)c(-c2c[nH]c3ccccc23)n1>>Cc1ccc(S(=O)(=O)n2cc(-c3nc(Cl)ncc3Br)c3ccccc32)cc1,,C1CCOC1,CN(C)C=O,O,[H-].[Na+],test
US20160002266A1,CC(C)N(C(=O)c1cnc(Cl)cc1CO)C(C)C>>O=C1OCc2cc(Cl)ncc21,,Cl,,O=C([O-])[O-].[Na+].[Na+],,test
US20070010560A1,N#CBr.Nc1ccc(Cl)c(C(F)(F)F)c1N>>Nc1nc2cc(Cl)c(C(F)(F)F)cc2[nH]1,,CO,,CC#N,O,test
US20120214767A1,COc1cc2c(cc1C)-c1noc(-c3noc(-c4ccccc4)c3C(F)(F)F)c1CC2>>Cc1cc2c(cc1O)CCc1c-2noc1-c1noc(-c2ccccc2)c1C(F)(F)F,,ClCCl,,BrB(Br)Br,,test
US20100249099A1,COc1cccc2c1nc(C(F)F)n2-c1nc(OC2CCN(C(=O)OC(C)(C)C)CC2)nc(N2CCOCC2)n1>>c1ccc2[nH]cnc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030176454A1,COc1ccc2c(c1)-c1ncnc(Cl)c1CC2.Cc1ncc(-c2cccc(N)c2)n1C>>COc1ccc2c(c1)-c1ncnc(Nc3cccc(-c4cnc(C)n4C)c3)c1CC2,,ClCCl,,[Na+].[OH-],,test
US20040242410A1,CC(C)c1cccc(C(C)C)c1N.CC1=C(C)C(c2ccccc2C=O)C(C)=C1C>>CC1=C(C)C(c2ccccc2C=Nc2c(C(C)C)cccc2C(C)C)C(C)=C1C,,CCO,,CC(=O)O,,test
US20040014802A1,Nc1n[nH]c2cc(Cl)ccc12.O=C(Cl)c1ccccn1>>O=C(Nc1n[nH]c2cc(Cl)ccc12)c1ccccn1,,c1ccncc1,,CCN(C(C)C)C(C)C,Cl,test
US06251897B1,COc1ccc(C=O)cc1OC1CCCC1.C[Mg]Br>>COc1ccc(C(C)O)cc1OC1CCCC1,,C1CCOC1,,[Cl-].[NH4+],,test
US20090098218A1,CCOC1=CCCc2cnc(-c3ccc(OC)cc3)nc21>>COc1ccc(-c2ncc3c(n2)C(=O)CCC3)cc1,,CC(=O)O,O,,,test
US20060194841A1,CC(C)C(=O)N(C)CC(CC(O)CO)(c1ccc(Cl)c(Cl)c1)N(C)C(=O)OC(C)(C)C>>CC(C)C(=O)N(C)CC(CC=O)(c1ccc(Cl)c(Cl)c1)N(C)C(=O)OC(C)(C)C,,C1CCOC1,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20100152240A1,CC(C)(C)OC(=O)c1cscc1CO.II>>CC(C)(C)OC(=O)c1cscc1CI,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05428038,BrC1CCCC1.O=c1ccc2cc(O)c(OCc3ccccc3)cc2o1>>O=c1ccc2cc(OC3CCCC3)c(O)cc2o1,,CN(C)C=O,,[I-].[K+],,test
US20110053940A1,COCCCc1ccc(SC)c(CO)c1>>COCCCc1ccc(SC)c(C=O)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US04985444,COC(=O)CCn1cc(-c2c(-c3ccccc3)nn3ccccc23)cc(C#N)c1=O>>N#Cc1cc(-c2c(-c3ccccc3)nn3ccccc23)cn(CCC(=O)O)c1=O,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20060178376A1,CCCCCN1C=Nc2cccc([N+](=O)[O-])c2C1O>>CCCCCN1C=Nc2cccc(N)c2C1O,[Pt],CCOC(C)=O,CO,,,test
US20060052599A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N[C@@H]1CCN(Cc2cccc(N)c2)C1>>CC(=O)Nc1cccc(CN2CC[C@@H](NC(=O)OC(C)(C)C)C2)c1,,ClCCl,,O,c1ccncc1,test
US20120232056A1,COC(=O)c1ccc2nc(-c3cc4ccccc4o3)c(NC(C)C)nc2c1>>CC(C)Nc1nc2cc(C(=O)O)ccc2nc1-c1cc2ccccc2o1,,CO,O,Cl,[Na+].[OH-],test
US20110201625A1,C[N+](C)(CCCCN)CCNC(=O)c1nc(Cl)c(N)nc1N.O=C(O)Cc1ccc(OCc2ccccc2)cc1.[Br-]>>C[N+](C)(CCCCNC(=O)Cc1ccc(OCc2ccccc2)cc1)CCNC(=O)c1nc(Cl)c(N)nc1N.[Br-],,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140336190A1,Br[Mg]c1ccccn1.Cc1cccc(C(=O)c2cc(-c3c(C)noc3C)cc3c2nc(C2CC2)n3C(=O)OC(C)(C)C)n1>>Cc1cccc(C(O)(c2ccccn2)c2cc(-c3c(C)noc3C)cc3[nH]c(C4CC4)nc23)n1,,C1CCOC1,,,,test
US20090048295A1,CCc1cccc(CC)c1-c1cc(Cl)c2c(n1)CCCC2=O>>CCc1cccc(CC)c1-c1cc(Cl)c2c(n1)CCCC2O,,CO,,[BH4-].[Na+],,test
US04806145,COc1cc(-n2nc(C)n(C(F)F)c2=O)c(Cl)cc1C>>Cc1cc(Cl)c(-n2nc(C)n(C(F)F)c2=O)cc1O,,ClCCl,,BrB(Br)Br,,test
US20090124625A1,C[Si](C)(C)C#CCCN.O=Cc1c(F)cccc1[N+](=O)[O-]>>C[Si](C)(C)C#CCCn1cc2c(F)cccc2n1,,Cc1ccccc1,,,,test
US20090054431A1,Nc1c([N+](=O)[O-])cc(F)c(F)c1F.O=Cc1ccc(O)cc1>>Nc1c([N+](=O)[O-])cc(F)c(Oc2ccc(C=O)cc2)c1F,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110237628A1,COC(=O)c1ccc(NC(=O)C(c2c3c(nn2-c2ccc(Cl)cc2)CCCCC3)C2CCCCC2)c(F)c1>>O=C(O)c1ccc(NC(=O)C(c2c3c(nn2-c2ccc(Cl)cc2)CCCCC3)C2CCCCC2)c(F)c1,,C1CCOC1,CO,[Li+].[OH-],,test
US05378690,O=C(O)C(=Cc1cccc2ccccc12)CCC(=O)N1CCOCC1>>O=C(O)C(CCC(=O)N1CCOCC1)Cc1cccc2ccccc12,[Pd],CO,,[H][H],,test
US20080262020A1,Cn1c(=O)c(-c2ccc(Cl)cc2Cl)cc2c3cc(-c4csc(CO)n4)ccc3n(C)c21>>Cn1c(=O)c(-c2ccc(Cl)cc2Cl)cc2c3cc(-c4csc(C=O)n4)ccc3n(C)c21,,ClC(Cl)Cl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US03932466,N#Cc1c(N)oc2ccccc2c1=O.O=S(=O)(O)O>>NC(=O)c1c(N)oc2ccccc2c1=O,,O,,,,test
US04855086,OCCCC#Cc1ccccc1>>O=CCCC#Cc1ccccc1,,CCOCC,ClCCl,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20120122843A1,CNCC(O)CC(F)(F)F.Clc1ccc(CBr)c(Cl)n1>>CN(Cc1ccc(Cl)nc1Cl)CC(O)CC(F)(F)F,,CC#N,,,,test
US20090137603A1,CC(=O)OC(C)=O.CC(C)C(CS(=O)(=O)c1ccc(-c2cccc(CNC(=O)c3nc4ccccc4c(=O)[nH]3)c2)cc1)NO>>CC(=O)N(O)C(CS(=O)(=O)c1ccc(-c2cccc(CNC(=O)c3nc4ccccc4c(=O)[nH]3)c2)cc1)C(C)C,,C1CCOC1,,CC(=O)O,,test
US20150018422A1,CC(=O)Cl.CCOC(=O)CC(c1cccc(CNc2ccc(-c3cc(OC)ccc3F)c(CC(C)(C)C)c2)c1)C1CC1>>CCOC(=O)CC(c1cccc(CN(C(C)=O)c2ccc(-c3cc(OC)ccc3F)c(CC(C)(C)C)c2)c1)C1CC1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US04933350,COC(=O)C(Br)c1ccccc1.COC(CN)OC>>COC(=O)Cc1ccccc1NCC(OC)OC,,CC#N,CCOCC,CCN(CC)CC,,test
US20050176994A1,CCOS(=O)(=O)OCC.COc1ccc(C(=O)/C=C/C(=O)O)cc1Cl>>CCOC(=O)/C=C/C(=O)c1ccc(OC)c(Cl)c1,,CN(C)C=O,,CC(=O)O,O=C([O-])[O-].[K+].[K+],test
US20120190677A1,CCOC(=O)c1ccc2c(c1)C(C)(C)CC(c1cccc(C(=O)O)c1)N2.CN>>CCOC(=O)c1ccc2c(c1)C(C)(C)CC(c1cccc(C(=O)NC)c1)N2,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100317675A1,Cl.O=C(Nc1ccccc1)c1cn2cc(-c3cn(C(c4ccccc4)(c4ccccc4)c4ccccc4)cn3)ccc2n1>>Cl.O=C(Nc1ccccc1)c1cn2cc(-c3c[nH]cn3)ccc2n1,,CO,Cl,ClCCl,,test
US20140113877A1,COc1cc(F)ccc1-c1cc2c(s1)c(=O)n(C1CCN(C(=O)OC(C)(C)C)CC1)c(=O)n2Cc1ccc(C)c(F)c1.Cl>>COc1cc(F)ccc1-c1cc2c(s1)c(=O)n(C1CCNCC1)c(=O)n2Cc1ccc(C)c(F)c1.Cl,,C1COCCO1,ClCCl,CCOCC,,test
US20160102058A1,Cl[Mg]C1CCCCC1.O=CC1CCC(F)(F)CC1>>OC(C1CCCCC1)C1CCC(F)(F)CC1,,C1CCOC1,,,,test
US20070004753A1,CN(C)C(=O)CCCc1ccc(N)cc1.C[Si](C)(C)C#N.O=C1CCC1>>CN(C)C(=O)CCCc1ccc(NC2(C#N)CCC2)cc1,,CCOC(C)=O,,,,test
US20160221945A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.O=C1CC[C@@H](CO)N1>>CC(C)(C)[Si](OC[C@@H]1CCC(=O)N1)(c1ccccc1)c1ccccc1,CN(C)c1ccncc1,ClCCl,O,c1c[nH]cn1,,test
US20140094474A1,CCOC(=O)c1noc(-c2cc(C)n(C)n2)n1>>Cc1cc(-c2nc(C(=O)O)no2)nn1C,,CCO,,[Na+].[OH-],,test
US20100036126A1,CCN(CC)CC.CCOC(=O)C(=O)Cl.CN1CCNC(c2ccccc2)C1>>CCOC(=O)C(N)=O.CN1CCNC(c2ccccc2)C1,,ClCCl,,,,test
US05932595,C=C1CC(C(=O)OC(C)(C)C)CCN1C(=O)OCc1ccccc1>>O=C(O)C=C1CCN(C(=O)OCc2ccccc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100190762A1,CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2C(=O)NN)cc1.CC(C)N.N#CBr>>CC(C)n1c(N)nnc1-c1cc(Cl)ccc1NS(=O)(=O)c1ccc(C(C)(C)C)cc1,,C1COCCO1,CC(=O)O,O=C([O-])[O-].[K+].[K+],,test
US20120258949A1,CN1CC2(CC(=O)c3cc(/C=C/C(=O)O)ccc3O2)C1.NOC1CCCCO1>>CN1CC2(CC(=O)c3cc(/C=C/C(=O)NOC4CCCCO4)ccc3O2)C1,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20080167361A1,Fc1ccc2[nH]ccc2c1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(c1ccccc1)n1ccc2cc(F)ccc21,,CN(C)C=O,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20090306041A1,BrBr.O=c1ccc(Br)cn1C(F)F>>O=c1c(Br)cc(Br)cn1C(F)F,,CC(=O)O,,,,test
US05231102,COC(=O)C[C@H]1C[C@H](C(=O)OC)Nc2cc(Cl)cc(Cl)c21>>O=C(O)C[C@H]1C[C@H](C(=O)O)Nc2cc(Cl)cc(Cl)c21,,CO,,[Na+].[OH-],,test
US05840917,CCOC(=O)c1cc(C)cs1.O=S(=O)(Cl)Cl>>CCOC(=O)c1cc(C)c(Cl)s1,,CC#N,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US04317819,CSC(C[N+](=O)[O-])SC.NC=C(SCc1ccco1)[N+](=O)[O-]>>CSC(=C[N+](=O)[O-])NCCSCc1ccco1,,C1COCCO1,,,,test
US05470845,CCCCc1ccc(Br)cc1.CCOC(=O)CCc1ccc(I)cc1>>CCCCc1ccc(-c2ccc(CCC(=O)OCC)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,CCOCC,[Li]C(C)(C)C,,test
US20130343992A1,CS(=O)(=O)Cl.OCCn1cc(-c2ccncc2)c(-c2ccc(OCc3ccc4ncccc4n3)cc2)n1>>CS(=O)(=O)OCCn1cc(-c2ccncc2)c(-c2ccc(OCc3ccc4ncccc4n3)cc2)n1,,ClCCl,,c1ccncc1,,test
US20100075994A1,C=CC(=O)OCC.CC(C)(C)c1ccc(OCC2CN=C(N)O2)cc1>>CC(C)(C)c1ccc(OCC2CN3CCC(=O)N=C3O2)cc1,,CCO,,,,test
US06492416B1,CSc1ccc(C2=C(c3ccccc3)C(=O)C(C)(C)O2)cc1Cl.O=C(OO)c1cccc(Cl)c1>>CS(=O)c1ccc(C2=C(c3ccccc3)C(=O)C(C)(C)O2)cc1Cl,,ClCCl,,O=C([O-])O.[Na+],,test
US20060252837A1,CN.COC(=O)c1cc(CCl)c(CCl)s1>>COC(=O)c1cc2c(s1)CN(C)C2,,CC#N,,,,test
US20040092582A1,COC(=O)c1ccc(Cn2ccc(C3=NC(C)(C)Cc4cc(OC)c5c(c43)CC(C)(C)O5)cc2=O)cc1.NCCO>>COc1cc2c(c3c1OC(C)(C)C3)C(c1ccn(Cc3ccc(C(=O)NCCO)cc3)c(=O)c1)=NC(C)(C)C2,,Cc1ccccc1C,,,,test
US20060241296A1,FC(F)(F)c1ccc(-c2cc(Cl)nc(Cl)n2)cc1.Nc1cccc2c1CC(O)CC2>>OC1CCc2cccc(Nc3cc(-c4ccc(C(F)(F)F)cc4)nc(Cl)n3)c2C1,,CCO,,,,test
US04855453,CCOC(=O)c1cc2ccc3ccc4ccccc4c3c2o1>>OCc1cc2ccc3ccc4ccccc4c3c2o1,,CCCCCC,ClCCl,,,test
US03957783,Cc1csc2c1c(-c1ccccc1)nc(=O)n2C.O=S(=O)(Cl)Cl>>Cc1c(Cl)sc2c1c(-c1ccccc1)nc(=O)n2C,,ClC(Cl)Cl,,N,,test
US06121258,[C-]#[N+]C(C(=O)OCC)C(C)(C)C(=O)OCC=C>>C=CCOC(=O)C(C)(C)C(N)C(=O)OCC,,CO,,Cl,[Na+].[OH-],test
US20110015373A1,C=Cc1ccc(N)cc1.FC(F)(F)c1cc(N=C=S)cc(C(F)(F)F)c1>>C=Cc1ccc(NC(=S)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1,,C1CCOC1,,,,test
US20110071150A1,CC(=O)c1ccccc1F.NNc1ccc(Br)cc1>>C/C(=N\Nc1ccc(Br)cc1)c1ccccc1F,,CCO,,CC(=O)[O-].[K+],,test
US20040048915A1,COC(=O)C(=O)c1cc(C)cc2ccn(C)c12.NC(=O)Cc1c[nH]c2cc(C(F)(F)F)ccc12>>Cc1cc(C2=C(c3c[nH]c4cc(C(F)(F)F)ccc34)C(=O)NC2=O)c2c(ccn2C)c1,,CN(C)C=O,,C1CCOC1,CC(C)(C)[O-].[K+],test
US20020169317A1,O=C1c2c(n3c4c(cccc24)OCC3c2ccccc2)CCC1Cl>>Oc1cccc2c1c1cccc3c1n2C(c1ccccc1)CO3,,CN(C)C=O,,[Cl-].[Li+],,test
US20040009988A1,Cc1cccc(C(=O)Nc2ccc(N3CCNCC3)nc2)c1-c1ccc(C(C)C)cc1.NC(=O)CBr>>Cc1cccc(C(=O)Nc2ccc(N3CCN(CC(N)=O)CC3)nc2)c1-c1ccc(C(C)C)cc1,,C1CCOC1,,CCN(CC)CC,,test
US05866592,CC(=O)O.Cl.N=C(N)c1ccc(C(N)=O)cc1>>Cl.N=C(N)c1ccc(C(=O)O)cc1,,Cl,,,,test
US20070203129A1,CC(=O)CCl.Cc1c(C(=O)O)cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n1-c1cccc(C(F)(F)F)c1.N>>Cc1coc(-c2cc(C(=O)NCc3ccc(S(C)(=O)=O)cc3)c(=O)n(-c3cccc(C(F)(F)F)c3)c2C)n1,,CN1CCCC1=O,,O=C([O-])[O-].[Ca+2],,test
US20160193310A1,CC(=O)N[C@@H]1[C@@H]([C@H](O)[C@H](O)CO)O[C@](O[C@@H]2[C@@H](O)[C@H](O[C@H]3[C@H](O)[C@@H](CO[C@]4(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CO)O4)O[C@@H](O[C@H]4[C@@H](O)[C@@H](CO)O[C@@H](OCCCCCN)[C@@H]4O)[C@@H]3NC(C)=O)O[C@H](CO)[C@@H]2O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2NC(C)=O)(C(=O)O)C[C@H]1O.O=C(CCSSCCC(=O)ON1C(=O)CC(S(=O)(=O)O)C1=O)ON1C(=O)CC(S(=O)(=O)O)C1=O.O[C@H](CS)[C@H](O)CS>>CC(=O)NC1[C@H](O[C@H]2[C@@H](CO)O[C@@H](O[C@H]3[C@H](O)[C@@H](CO[C@]4(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CO)O4)O[C@@H](O[C@H]4[C@@H](O)[C@@H](CO)O[C@@H](OCCCCCNC(=O)CCS)[C@@H]4O)[C@@H]3NC(C)=O)[C@H](O)[C@H]2O[C@@]2(C(=O)O)C[C@@H](O)[C@H](NC(C)=O)[C@@H]([C@H](O)[C@H](O)CO)O2)O[C@H](CO)[C@H](O)[C@@H]1O,,O=P([O-])([O-])[O-],,,,test
US20060058391A1,CCOC(=O)CCc1cccc(O)c1.O=[N+]([O-])c1cccc(S(=O)(=O)OC[C@H]2CO2)c1>>CCOC(=O)CCc1cccc(OC[C@H]2CO2)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120208817A1,CCOc1cc(C=O)cc(SC)c1O.NC(N)=O.O=C(Cc1ccccc1)c1ccccc1>>CCOc1cc(C2NC(=O)NC(c3ccccc3)=C2c2ccccc2)cc(SC)c1O,,CCO,,Cl,,test
US20030036612A1,CN(C)C=O.c1ccc(-c2ccsc2-c2ccccc2)cc1>>O=Cc1cc(-c2ccccc2)c(-c2ccccc2)s1,,O,,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US20090124612A1,Cc1cc(Cl)nnc1Cl.OB(O)c1ccccc1>>Cc1cc(-c2ccccc2)nnc1Cl,,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04908371,COCCn1ccc(=O)c(OCc2ccccc2)c1C.Cl>>COCCn1ccc(=O)c(O)c1C.Cl,,CC(C)O,,,,test
US20150166480A1,COC(=O)c1cnc(-c2ccc(OCC3CCN(C(=O)OC(C)(C)C)CC3)cc2)cn1.Cl>>COC(=O)c1cnc(-c2ccc(OCC3CCNCC3)cc2)cn1.Cl,,ClCCl,,C1COCCO1,,test
US20130345212A1,CCOC(=O)Cn1ccc(C)n1.COC(=O)c1cc(-c2ccc(N(C)C)cc2)c(Cl)cc1N>>Cc1ccn(-c2c(O)c3cc(-c4ccc(N(C)C)cc4)c(Cl)cc3[nH]c2=O)n1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20150175604A1,BrCc1ccccc1.O=Cc1cc2nc(Cl)ccc2n1S(=O)(=O)c1ccccc1>>O=Cc1cc2nc(Cl)ccc2n1Cc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110021537A1,CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)OCc3ccccc3)n(-c3ccc(F)c(F)c3)n2)CC1>>CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)O)n(-c3ccc(F)c(F)c3)n2)CC1,,CCOC(C)=O,,,,test
US04898874,Cc1cccc(C(=O)c2ccc(C(F)(F)F)cc2)c1N>>Cc1cccc2c(-c3ccc(C(F)(F)F)cc3)onc12,,CC(=O)O,,OO,,test
US20150191461A1,Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnn(CCO[Si](C)(C)C(C)(C)C)c2)c1>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnn(CCO)c2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05733935,C#CCBr.CONC(=O)OC>>C#CCN(OC)C(=O)OC,,C1CCOC1,,O,[H-].[Na+],test
US20070161685A1,NC(Cc1ccccc1)(c1cccc(C(F)(F)F)c1)c1ccccn1.S=C=Nc1cccc(Cl)c1>>FC(F)(F)c1cccc(C(Cc2ccccc2)(NC(=S)Nc2cccc(Cl)c2)c2ccccn2)c1,,C1COCCO1,,,,test
US20090111864A1,CO.N#CC1(Nc2ccc(CCCC(=O)O)cc2)CCC1.N#Cc1ccc(N=C=S)cc1C(F)(F)F.O>>COC(=O)CCCc1ccc(N2C(=S)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C23CCC3)cc1,,O,,CN(C)C=O,Cl,test
US06617325B1,BrCCCBr.CCC(CC(=O)OC)c1ccccc1>>CCC(CCCBr)(CC(=O)OC)c1ccccc1,,C1CCOC1,CCCCCC,CC(C)NC(C)C,[Li]CCCC,test
US20090298807A1,Cc1ccc(C(=O)O)s1.c1ccc(C(c2ccccc2)N2CC3(CNCCO3)C2)cc1>>Cc1ccc(C(=O)N2CCOC3(C2)CN(C(c2ccccc2)c2ccccc2)C3)s1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020006943A1,CNOC.O=C(O)c1ccc[nH]1>>CON(C)C(=O)c1ccc[nH]1,CN(C)C=O,CCOC(C)=O,ClCCl,Cl,O=C(Cl)C(=O)Cl,test
US20060178438A1,CC(=S)NCCSc1ccccn1.COS(=O)(=O)C(F)(F)F>>CSC(C)=NCCSc1ccccn1,,ClCCl,,,,test
US20140159015A1,Brc1cnc(Br)cn1.Cc1ccc(N(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)c2ccc(C)cc2C)c(C)c1>>Cc1ccc(N(c2ccc(-c3cnc(Br)cn3)cc2)c2ccc(C)cc2C)c(C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20050048424A1,COC(=O)c1cc(C=O)ccc1OC>>COC(=O)c1cc(CO)ccc1OC,,CO,,[BH4-].[Na+],,test
US20130059835A1,CCOc1c(C(C)O)cc(Cl)c(C)c1C1CN(C(=O)OCc2ccccc2)C1.Clc1nc(Cl)nc(Cl)n1>>CCOc1c(C(C)Cl)cc(Cl)c(C)c1C1CN(C(=O)OCc2ccccc2)C1,,ClCCl,ClCCl,CN(C)C=O,O,test
US03994974,BrBr.CC(=O)c1ccc(O)c([N+](=O)[O-])c1>>O=C(CBr)c1ccc(O)c([N+](=O)[O-])c1,,ClC(Cl)Cl,,,,test
US20100190688A1,C=C[Mg]Br.CC(C)(C)OC(=O)N1C(=O)CC[C@H]1C(=O)OCc1ccccc1>>C=CC(=O)CCC(NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1,,C1CCOC1,,,,test
US05177075,O=C1NCCc2c(O)cccc21.OC(Br)CCCl>>O=C1NCCc2c(OCCCCl)cccc21,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20080306125A1,CO.O=C(O)Cc1ccc(Br)cc1[N+](=O)[O-]>>COC(=O)Cc1ccc(Br)cc1[N+](=O)[O-],,CO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20060089392A1,CCOC(=O)CCc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)c(C(=O)N(C)C)c1>>CN(C)C(=O)c1cc(CCC(=O)O)ccc1NC(=O)c1ccccc1-c1ccc(C(F)(F)F)cc1,,CCO,,[Na+].[OH-],,test
US20140135318A1,CCCCN(CCCC)C(=O)c1nn(-c2ccc(C(=O)NS(=O)(=O)c3ccc4ccccc4c3)cc2C(=O)O)c(C)c1Cl.CN(C)C1=NCc2ccccc2CN1>>CCCCN(CCCC)C(=O)c1nn(-c2ccc(C(=O)NS(=O)(=O)c3ccc4ccccc4c3)cc2C(=O)N2Cc3ccccc3CN=C2N(C)C)c(C)c1Cl,CN(C)c1ccncc1,C1CCOC1,ClCCCl,CCN(C(C)C)C(C)C,,test
US20110053936A1,BrBr.CC(=O)c1ccc(C)c(Br)c1>>Cc1ccc(C(=O)CBr)cc1Br,,ClC(Cl)Cl,,,,test
US20040092521A1,O=c1cccn[nH]1.OCCc1ccc2cc(Br)ccc2c1>>O=c1cccnn1-c1ccc2cc(CCO)ccc2c1,[Cu],c1ccncc1,,O=C([O-])[O-].[K+].[K+],,test
US06080895,Cc1cccc(C=O)c1OCc1ccccc1.O=C(OO)c1cccc(Cl)c1>>Cc1cccc(O)c1OCc1ccccc1,,ClCCl,,Cl,[Na+].[OH-],test
US06403534B1,COC(=O)C(CCBr)Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl>>COC(=O)C1(Oc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2Cl)CC1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US08304419B2,C[Si](C)(C)CCOCn1cnc(Cl)c1C(=O)NCc1ccc(Cl)c(Oc2ccc(F)c(C#N)c2)c1F>>N#Cc1cc(Oc2c(Cl)ccc(CNC(=O)c3[nH]cnc3Cl)c2F)ccc1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140179715A1,CC(C)(C)OC(=O)N1CCn2c1cc(OCc1cnc(Oc3cccc(C(F)(F)F)c3)c(C#N)c1)nc2=O>>N#Cc1cc(COc2cc3n(c(=O)n2)CCN3)cnc1Oc1cccc(C(F)(F)F)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050119246A1,CCC(=O)C(Cc1ccc(Br)cc1)C(=O)CC.NN>>CCc1n[nH]c(CC)c1Cc1ccc(Br)cc1,,CCO,,,,test
US05196434,CCCN.O=C1COc2ccc(CCBr)cc2N1>>CCCNCCc1ccc2c(c1)NC(=O)CO2,,CN(C)C=O,,CCN(CC)CC,,test
US20100094000A1,Cc1nn(CC(F)(F)CO)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2.O=C(O)c1cccnc1>>Cc1nn(CC(F)(F)COC(=O)c2cccnc2)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2,,c1ccncc1,,CCN=C=NCCCN(C)C,Cl,test
US04140789,C=CCBr.COC(=O)c1cccc(O)c1C(=O)OC>>C=CCOc1cccc(C(=O)OC)c1C(=O)OC,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20160024060A1,CC(=O)c1ccc(C(C)=O)c2c(C)c(C(=O)Nc3cc(C(C)(C)O)c4ccccc4n3)sc12.CS(=O)(=O)O>>CC(=O)c1ccc(C(C)=O)c2c(C)c(C(=O)Nc3cc(C(C)(C)O)c4ccccc4n3)sc12.CS(=O)(=O)O,,CC(C)O,,,,test
US20130217680A1,C=CC[Sn](CCCC)(CCCC)CCCC.N#Cc1cccc(Br)c1>>C=CCc1cccc(C#N)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,[Cl-].[Li+],,test
US20100273806A1,CCOC(=O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cnc(F)c(C)c4)n3)cc21.CO>>CCOC(=O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4cnc(OC)c(C)c4)n3)cc21,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20160008490A1,O=C1c2ccccc2C(=O)N1CCCc1ccc(O)cc1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=C1c2ccccc2C(=O)N1CCCc1ccc(OS(=O)(=O)C(F)(F)F)cc1,,c1ccncc1,,CCOCC,O,test
US20070249587A1,CC(C)(C)OC(=O)N1CCN(C(=O)CCO)CC1.Cl>>Cl.O=C(CCO)N1CCNCC1,,CO,,C1COCCO1,,test
US20010037023A1,CCOC(=O)CCBr.N#CC(CCCOC1CCOCC1)c1ccc(Cl)c(Cl)c1>>CCOC(=O)CCC(C#N)(CCCOC1CCOCC1)c1ccc(Cl)c(Cl)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US04213978,CCCCCCCCCCO.Cl.N[C@@H](CS)C(=O)O>>CCCCCCCCCCOC(=O)[C@@H](N)CS.Cl,,CCOC(C)=O,,,,test
US20110152238A1,C=CCBr.CCN(CC)C(=O)c1ccc(C(c2cccc(OC)c2)N2C3CCC2C2CCC3N2)cc1>>C=CCN1C2CCC1C1CCC2N1C(c1ccc(C(=O)N(CC)CC)cc1)c1cccc(OC)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140171390A1,CC(C)(C)OC(=O)NCCBr.COc1c(CC(NC(=O)CC2CCC(CN)CC2)B2OC3CC4CC(C4(C)C)C3(C)O2)cccc1C(=O)OC(C)(C)C>>COc1c(CC(NC(=O)CC2CCC(CNCCNC(=O)OC(C)(C)C)CC2)B2OC3CC4CC(C4(C)C)C3(C)O2)cccc1C(=O)OC(C)(C)C,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100172867A1,Cc1ccc(S(=O)(=O)N2CCC(NC(=O)OC(C)(C)C)Cc3ccccc32)cc1>>CC(C)(C)OC(=O)NC1CCNc2ccccc2C1,,CO,,[Mg],,test
US09428456B2,Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1.O=C(Cl)c1ccc(Cl)cc1>>O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1ccc(Cl)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070299092A1,CCN(CC)CC.COCCOc1cc2ncnc(NC3=CC(=O)C(Cl)=CC3=O)c2cc1OC.COc1ccccc1CC1CCNCC1>>COCCOc1cc2ncnc(NC3=CC(=O)C(N(Cc4ccccc4)c4ccc(OC)cc4)=CC3=O)c2cc1OC,,ClCCl,,,,test
US20120184553A1,Nc1cnoc1.O=C(O)c1cc(-c2ccncc2)ccc1OCc1ccccc1>>O=C(Nc1cnoc1)c1cc(-c2ccncc2)ccc1OCc1ccccc1,,CN(C)C=O,O,ClCCCl,On1nnc2ccccc21,test
US20070149542A1,Fc1c(C2=CCNCC2)cccc1C(F)(F)F>>Fc1c(C2CCNCC2)cccc1C(F)(F)F,[Pd],CO,,Cl,,test
US20080207654A1,CCCc1nc(C(C)N2CCOCC2)cc(=O)n1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCc1nc(C(C)N2CCOCC2)cc(=O)n1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20140303168A1,CS(=O)(=O)Cl.Nc1cncc(-c2nnc(NCc3ccccc3)c3c(-c4ccccc4)cccc23)c1>>CS(=O)(=O)Nc1cncc(-c2nnc(NCc3ccccc3)c3c(-c4ccccc4)cccc23)c1,,ClCCl,,c1ccncc1,,test
US20050256103A1,COc1cc2c(c(OC)c1)C(=O)CC2.O=C1CCC(=O)N1Br>>COc1cc(OC)c2c(c1Br)CCC2=O,,ClCCl,,ClC(Cl)Cl,,test
US05112817,CC(C)=O.ClCC1CO1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>Cc1cc2cccnc2cc1O,,CC(C)=O,,CCN(CC)CC,,test
US20100249163A1,COCCCc1cc(CN(C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CC[C@]2(O)c2ccc(Cl)c(C(F)(F)F)c2)C2CC2)cc(OCCOC)c1>>COCCCc1cc(CN(C(=O)C2CNCCC2(O)c2ccc(Cl)c(C(F)(F)F)c2)C2CC2)cc(OCCOC)c1,,ClCCl,,Cl,,test
US06277862B1,CC[C@H](NC(=O)c1c(OCCN)c(-c2ccccc2)nc2ccccc12)c1ccccc1.O=C(Cl)c1ccccc1>>CC[C@H](NC(=O)c1c(OCCNC(=O)c2ccccc2)c(-c2ccccc2)nc2ccccc12)c1ccccc1,,ClCCl,,,,test
US20080207639A1,COC(=O)c1ccccc1-c1cc(OC)c(OC)c(OC)c1>>COc1cc(-c2ccccc2C(=O)O)cc(OC)c1OC,,CO,,[Li+].[OH-],,test
US20040122084A1,CC(=O)OC(C)=O.CC1CCN(C2C3=CC(OC3=O)C3C(CC4(C)OC4C2O)OC(=O)C3C)CC1>>CC(=O)OC1C(N2CCC(C)CC2)C2=CC(OC2=O)C2C(CC3(C)OC13)OC(=O)C2C,,c1ccncc1,,O,,test
US20090076004A1,CCOC(=O)C=Cc1c(C(=O)OCC)n(-c2ccc(OC(C)C)cc2)c2ccc(-c3ccc(C(F)(F)F)cn3)cc12>>CCOC(=O)CCc1c(C(=O)OCC)n(-c2ccc(OC(C)C)cc2)c2ccc(-c3ccc(C(F)(F)F)cn3)cc12,[Pd],CCO,,C1=CCCCC1,,test
US20100122729A1,CCCCI.CCOCC.CN(C)C=O.Nc1ccc2c(c1)Cc1cc(Br)ccc1-2>>CCCCN(CCCC)c1ccc2c(c1)Cc1cc(Br)ccc1-2,,O,,O=C([O-])[O-].[K+].[K+],,test
US20120083469A1,CC(C)(C)OC(=O)N1CC(=O)O[C@@H](c2ccccc2)[C@H]1c1ccccc1.CC1(C)OB(CCCCI)OC1(C)C>>CC(C)(C)OC(=O)N1[C@H](c2ccccc2)[C@H](c2ccccc2)OC(=O)[C@H]1CCCCB1OC(C)(C)C(C)(C)O1,,C1CCOC1,CN(C)P(=O)(N(C)C)N(C)C,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20110092558A1,O=C(O)CCCc1c(Cl)cc(Cl)cc1Cl.[Li]C>>CC(=O)CCCc1c(Cl)cc(Cl)cc1Cl,,O,,CCOCC,,test
US20150299190A1,CC(C)(C)OC(=O)c1ccc(N2CCOCS2(=O)=O)cc1>>O=C(O)c1ccc(N2CCOCS2(=O)=O)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20090082434A1,Cc1ccc(S(=O)(=O)OCC2Cc3cccc(OS(=O)(=O)C(F)(F)F)c3O2)cc1.c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>Cc1ccc(S(=O)(=O)OCC2Cc3cccc(-c4cccc(C)c4)c3O2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US05631210,CC(C)=CCSc1cc(C)cs1>>Cc1csc2c1C(C)(C)CCS2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040181064A1,CC(O)[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)CCN1C(=O)OC(C)(C)C.NO>>CC(=NO)[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)CCN1C(=O)OC(C)(C)C,,CO,O,Cl,c1ccncc1,test
US20140005382A1,O=C(N1CCc2cc(S(=O)(=O)Nc3ccc(OCCc4ccccn4)cc3F)ccc2C1)C(F)(F)F>>O=S(=O)(Nc1ccc(OCCc2ccccn2)cc1F)c1ccc2c(c1)CCNC2,,CCO,O,[K+].[OH-],,test
US20120149694A1,O=C(N1CCOCC1)N1CC(CS(=O)(=O)[O-])CC(c2ccc(C(F)(F)F)cc2)C1.Sc1ccccc1>>O=C(N1CCOCC1)N1CC(CSc2ccccc2)CC(c2ccc(C(F)(F)F)cc2)C1,,CN(C)C=O,,O,[H-].[Na+],test
US04684220,CCCCCCOc1ccc(Br)cc1.[Li]CCCC>>[Li]c1ccc(OCCCCCC)cc1,,c1ccccc1,,CCCCCC,,test
US20140051679A1,CC1(C)OB(c2ccc(OC3CCN(C=O)CC3)cc2)OC1(C)C.O=C(Nc1ccc2[nH]nc(I)c2c1)C(c1ccccn1)C1CCCC1>>O=CN1CCC(Oc2ccc(-c3n[nH]c4ccc(NC(=O)C(c5ccccn5)C5CCCC5)cc34)cc2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US04720586,BrB(Br)Br.COc1ccc(CCNCC/C=C/CCNCCc2ccccc2)cc1OC>>Br.Br.Oc1ccc(CCNCC/C=C/CCNCCc2ccccc2)cc1O,,ClCCl,,C1=CCCCC1,,test
US20080280892A1,CC(C)(C)OC(=O)NC[C@H]1CCN(CC2Cn3c(=O)ccc4ccc(F)c2c43)C1>>NC[C@H]1CCN(CC2Cn3c(=O)ccc4ccc(F)c2c43)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100029611A1,O=C(c1ccccc1)c1ccc2nc(-c3ccc(C4OCCCO4)cc3F)sc2n1>>OC(c1ccccc1)c1ccc2nc(-c3ccc(C4OCCCO4)cc3F)sc2n1,,C1CCOC1,CO,[BH4-].[Na+],[Cl-].[NH4+],test
US06423870B1,COc1ccc2ccccc2c1C(C)=CC(=O)O>>COc1ccc2ccccc2c1CCCC(=O)O,[Pd],,,CCOC(C)=O,,test
US20150018332A1,COC(=O)C1CN(C(=O)/C=C\n2cnc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C1>>O=C(O)C1CN(C(=O)/C=C\n2cnc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C1,,CO,,O,[Li+].[OH-],test
US06458796B1,CC(CCCc1ccccc1)n1nnc(C(N)=O)c1N.COC(=O)Cc1ccc(C)cc1>>Cc1ccc(Cc2nc3c(nnn3C(C)CCCc3ccccc3)c(=O)[nH]2)cc1,,CCO,,[Na],,test
US20010027198A1,CC1(C)NC(=O)c2ccccc2O1.CCOC(=O)C(Cc1ccc(OCCBr)cc1)OCC>>CCOC(=O)C(Cc1ccc(OCCN2C(=O)c3ccccc3OC2(C)C)cc1)OCC,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20020016472A1,CC(=O)Oc1cc2oc(=O)cc(C=[N+]=[N-])c2cc1Br>>[N-]=[N+]=Cc1cc(=O)oc2cc(O)c(Br)cc12,[Zn],CO,,,,test
US20140155391A1,CC(C)(C)OC(=O)CC(=O)O.COc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1N>>COc1ccc(C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1NC(=O)CC(=O)OC(C)(C)C,CN(C)c1ccncc1,CN(C)C=O,,ClCCCl,,test
US20070281975A1,O=C(O)[C@@H](O)[C@H](O)C(=O)O.OC[C@H]1CNC[C@@H](O)[C@@H]1O>>O=C([O-])[C@@H](O)[C@H](O)C(=O)[O-].OC[C@H]1CNC[C@@H](O)[C@@H]1O,,O,,,,test
US20100105917A1,N[C@@H]1CCCN(C(=O)c2ccc(Cl)cc2)C1.O=C(Cl)c1ccc(Cl)cc1>>O=C(N[C@@H]1CCCN(C(=O)c2ccc(Cl)cc2)C1)c1ccc(Cl)cc1,,Clc1ccccc1,,[Na+].[OH-],,test
US20090291950A1,COc1ccc2c(c1OC1CCCC1)OCCC2=NO>>COc1ccc2c(c1OC1CCCC1)OCCC2N,[Pd],C1CCOC1,,CO,,test
US20110053904A1,CCCCN.O=Cc1c(F)cc(C(F)(F)F)cc1C(F)(F)F>>CCCCN=Cc1c(F)cc(C(F)(F)F)cc1C(F)(F)F,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100152450A1,O=C(OCc1ccccc1)N1CC[C@H]1COc1cncc(-c2cccc(CCO)c2)c1>>OCCc1cccc(-c2cncc(OC[C@@H]3CCN3)c2)c1,[Pd],CO,,,,test
US03966953,C=CCN=C=O.CCN1C(=O)CSC1=NO>>C=CCNC(=O)ON=C1SCC(=O)N1CC,CCN(CC)CC,CC#N,ClC(Cl)Cl,,,test
US20160016951A1,CC(C)(C)OC(=O)NCCNC(=O)c1ccc2cncc(Br)c2n1.CN1c2ccc(B3OC(C)(C)C(C)(C)O3)cc2CS1(=O)=O>>CN1c2ccc(-c3cncc4ccc(C(=O)NCCNC(=O)OC(C)(C)C)nc34)cc2CS1(=O)=O,,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20070167449A1,O=CCc1ccccc1Cl.Oc1ccc(Nc2ncc(-c3ccsc3)s2)cc1>>Oc1ccc(Nc2ncc(-c3ccccc3Cl)s2)cc1,,CO,ClCCl,,,test
US20080119488A1,Cc1ccc(Cn2c(-c3cccc(Br)c3)cc(C(F)(F)F)c(C#N)c2=O)c(C)c1.OB(O)c1cccc(O)c1>>Cc1ccc(Cn2c(-c3cccc(-c4cccc(O)c4)c3)cc(C(F)(F)F)c(C#N)c2=O)c(C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,N#N,O=C([O-])[O-].[K+].[K+],test
US20060035898A1,COC(=O)c1cccc(-c2cnc3[nH]ncc3c2)c1.O=C1CCC(=O)N1I>>COC(=O)c1cccc(-c2cnc3[nH]nc(I)c3c2)c1,,CC(Cl)Cl,,,,test
US20130156700A1,C1COCCN1.COc1cc(C(=O)O)c(F)cc1N>>COc1cc(C(=O)N2CCOCC2)c(F)cc1N,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050014812A1,COc1cccc(-c2cc(C)c3nc(C)n(Cc4ccc(Cl)cc4Cl)c3c2)c1>>Cc1cc(-c2cccc(O)c2)cc2c1nc(C)n2Cc1ccc(Cl)cc1Cl,,ClCCl,,BrB(Br)Br,,test
US20060019985A1,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.N[C@H]1CCN(Cc2ccccc2)C1>>CC(C)(C)OC(=O)N1CCC(C(=O)N[C@H]2CCN(Cc3ccccc3)C2)CC1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20150266857A1,NCCO.O=S(=O)(c1ccccc1)n1cc(-c2ccc3nc(CCl)[nH]c3c2)c2ccc(F)cc21>>O=S(=O)(c1ccccc1)n1cc(-c2ccc3nc(CNCCO)[nH]c3c2)c2ccc(F)cc21,,CN(C)C=O,,,,test
US20150299122A1,CNC(=O)[C@H]1N[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O.ClC/C=C/c1ccc(-c2ccccc2)cc1>>CNC(=O)[C@@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)N1C/C=C/c1ccc(-c2ccccc2)cc1,,CN(C)C=O,,Cl,[I-].[K+],test
US20110172193A1,COc1c(N2CCCC(=C(F)CNC(=O)[C@H](CN(C)C)NC(=O)OC(C)(C)C)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12.Cl.ClCCl>>COc1c(N2CCCC(=C(F)CNC(=O)[C@@H](N)CN(C)C)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12.Cl.Cl,,ClCCl,,C1COCCO1,,test
US20120258952A1,CC(C)N1CCN(CCO)CC1.Cc1cccc(Cn2nc(C3CC3)c3c(NC(=O)c4cnc5cc(F)ccn45)cccc32)n1>>Cc1cccc(Cn2nc(C3CC3)c3c(NC(=O)c4cnc5cc(OCCN6CCN(C(C)C)CC6)ccn45)cccc32)n1,,O,,CC(C)(C)O,CC(C)(C)[O-].[K+],test
US20100267697A1,CC(C)(C)OC(=O)N(Cc1ccc(NC2CC2)cc1)c1ccc(F)cc1.CC=O>>CCN(c1ccc(CN(C(=O)OC(C)(C)C)c2ccc(F)cc2)cc1)C1CC1,,CCOC(C)=O,ClCCl,CC(=O)O,[Na+].[OH-],test
US20070021414A1,COc1ccc(C2(O)CCN(CC(=O)c3ccc(OCc4ccccc4)c(F)c3)CC2)cn1>>COc1ccc(C2(O)CCN(CC(O)c3ccc(OCc4ccccc4)c(F)c3)CC2)cn1,,CCO,,[BH4-].[Na+],,test
US20100048556A1,CCOC(=O)CCc1ncc[nH]1.O=[N+]([O-])c1cc(F)ccc1F>>CCOC(=O)CCc1nccn1-c1ccc(F)cc1[N+](=O)[O-],,CCOC(C)=O,,CC(=O)N(C)C,O=C([O-])[O-].[K+].[K+],test
US20120157425A1,CCOc1ccc(N2CCC(c3ccc([C@H](C)N)cc3)CC2)cc1.CN.O=C(n1ccnc1)n1ccnc1>>CCOc1ccc(N2CCC(c3ccc([C@H](C)NC(=O)NC)cc3)CC2)cc1,,CN(C)C=O,,,,test
US20060160864A1,CC1CCN(c2ccc(Br)cc2C=O)C1.CCOC(=O)C(C)P(=O)(OCC)OCC>>CCOC(=O)/C(C)=C/c1cc(Br)ccc1N1CCC(C)C1,,Cc1ccccc1,,O,[H-].[Na+],test
US04629799,C/C=C/C=O.CCN(CC)CC.Cc1ccccc1.S>>CC1CC=C(C=O)C(C)S1,,CCN(CC)CC,,O=P(O)(O)O,,test
US04743604,COC(=O)C=O.COC(=O)c1ccc(CCCNC[C@H](O)c2ccccc2)s1>>COC(=O)c1ccc(CCCN2C[C@@H](c3ccccc3)OC2C(=O)OC)s1,,CCOC(C)=O,Cc1ccccc1,O,,test
US20100298336A1,Cc1cc(O)nc(SCc2cncn2C2CCCCC2)n1.Cl>>Cc1cc(O)nc(SCc2cncn2C2CCCCC2)n1.Cl,,CO,,C1COCCO1,,test
US20140256740A1,COC(=O)CN1CCN(CCc2c(C)noc2C)CC1>>Cc1noc(C)c1CCN1CCN(CC(=O)O)CC1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20100144732A1,Nc1ccc(N2CCOCC2)cc1.O=C(Nc1cc(Cl)ccc1Nc1nc(Cl)ncc1Cl)C1CC1>>O=C(Nc1cc(Cl)ccc1Nc1nc(Nc2ccc(N3CCOCC3)cc2)ncc1Cl)C1CC1,,CCCCO,,Cl,,test
US05244903,Nc1cc([N+](=O)[O-])ccc1C=O>>Nc1ccc(C=O)c(N)c1,[Pd],,,,,test
US20080221335A1,ClP(Cl)Cl.Oc1nccc(-c2cccc(P(c3ccccc3)c3ccccc3)c2)n1>>Clc1nccc(-c2cccc(P(c3ccccc3)c3ccccc3)c2)n1,,ClC(Cl)Cl,,,,test
US20130345212A1,COC(=O)c1cc(-c2ccc3c(ccn3C)c2)c(Cl)cc1N.COC(=O)c1cccc(CC(=O)O)c1>>COC(=O)c1cccc(CC(=O)Nc2cc(Cl)c(-c3ccc4c(ccn4C)c3)cc2C(=O)OC)c1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020161237A1,CCOC(=O)CC(=O)C(C)C.O=S(=O)(Cl)Cl>>CCOC(=O)CC(=O)C(C)(C)Cl,,ClCCl,,,,test
US20060293353A1,CC(C)(C)OC(=O)C(CCO[Si](C)(C)C(C)(C)C)C(=O)CCc1ccc(I)cc1>>CC(C)(C)OC(=O)C(CCO[Si](C)(C)C(C)(C)C)C(O)CCc1ccc(I)cc1,,CO,,[BH4-].[Na+],,test
US20030220348A1,COc1nc(-c2ccccc2)cnc1CCl.c1c[nH]c(-c2nccs2)n1>>COc1nc(-c2ccccc2)cnc1Cn1ccnc1-c1nccs1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120122848A1,CI.O=C(OCc1ccccc1)N1CC[C@]23CCCC[C@H]2[C@H]1Cc1cc([N+](=O)[O-])c(O)cc13>>COc1cc2c(cc1[N+](=O)[O-])C[C@@H]1[C@@H]3CCCC[C@]23CCN1C(=O)OCc1ccccc1,,CC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100256363A1,C=CC[Mg]Br.CC(=O)c1ccccc1>>C=CCC(C)(O)c1ccccc1,,C1CCOC1,,,,test
US04311700,CN1C(=O)c2cncnc2N(C(=O)CCl)c2ccccc21.CN1CCNCC1>>CN1CCN(CC(=O)N2c3ccccc3N(C)C(=O)c3cncnc32)CC1,,c1ccccc1,,O=C([O-])O.[Na+],,test
US20090253705A1,CC(C)(C)OC(=O)N/N=C(\C#C[Si](C)(C)C)CCCC(=O)O>>CC(C)(C)OC(=O)n1ccc(CCCC(=O)O)n1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US07709479B1,C#CC(C)(C)O.CSc1ncnc2cc(OS(=O)(=O)C(F)(F)F)ccc12>>CSc1ncnc2cc(C#CC(C)(C)O)ccc12,[Cu]I,CN(C)C=O,,CCN(CC)CC,,test
US20110112063A1,CS(=O)(=O)Cl.Cc1cc(Nc2nc(Nc3cc(C)c(C4CCNCC4)cc3F)ncc2Cl)n[nH]1>>Cc1cc(Nc2nc(Nc3cc(C)c(C4CCN(S(C)(=O)=O)CC4)cc3F)ncc2Cl)n[nH]1,,CN(C)C=O,,CCN(CC)CC,,test
US20140045872A1,Cc1ccncc1N1CCc2ccc(N)cc2C1=O.O=C(Cl)C1CC1>>Cc1ccncc1N1CCc2ccc(NC(=O)C3CC3)cc2C1=O,,C1CCOC1,,,,test
US20120071489A1,CC(C)(C)c1ccccc1N1CCN(C(=O)C(=O)O)CC1.CC(C)NCc1ccccc1>>CC(C)N(Cc1ccccc1)C(=O)C(=O)N1CCN(c2ccccc2C(C)(C)C)CC1,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20130079478A1,N.O=C(NN1CCCCC1)N(C1CCCCC1)C1CCCCC1>>NC(=NN1CCCCC1)N(C1CCCCC1)C1CCCCC1,,C1CCOC1,CCOCC,O=C(Cl)C(=O)Cl,,test
US20040116328A1,CC#CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2nc(Cl)[nH]c(=O)c21.N#Cc1cccc(CBr)c1>>CC#CCn1c(N2CCN(C(=O)OC(C)(C)C)CC2)nc2nc(Cl)n(Cc3cccc(C#N)c3)c(=O)c21,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20030018045A1,CC(C)(C)[Si](Oc1ccc(OC[C@@H](O)CNCCc2ccc(NC3CCN(c4nc(-c5ccccc5)cs4)CC3)cc2)cc1)(c1ccccc1)c1ccccc1>>Oc1ccc(OC[C@@H](O)CNCCc2ccc(NC3CCN(c4nc(-c5ccccc5)cs4)CC3)cc2)cc1,,CO,ClC(Cl)Cl,,,test
US20070244118A1,CC(C)(C)OC(=O)N1CCCC(=O)N1C1CCN(C(=O)OCc2ccccc2)CC1>>O=C1CCCNN1C1CCNCC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20150315380A1,CC(C)(c1ccc(O)cc1)c1ccc(O)cc1>>CC(C)(C)c1ccc(O)cc1,,O,,[Na+].[OH-],,test
US20140155406A1,CC#CC(=O)O.Cc1nccn2c([C@@H]3CCCN3)nc(-c3ccc(C(=O)Nc4ccccn4)cc3)c12>>CC#CC(=O)N1CCC[C@H]1c1nc(-c2ccc(C(=O)Nc3ccccn3)cc2)c2c(C)nccn12,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110212053A1,BrBr.c1cncc(-c2ccc3ncc4[nH]ncc4c3c2)c1>>Brc1n[nH]c2cnc3ccc(-c4cccnc4)cc3c12,,ClCCl,O,Cl,[Na+].[OH-],test
US20090137557A1,NCCc1cccc(F)c1.O=C(O)C1CCCCC12OCCO2>>O=C(NCCc1cccc(F)c1)C1CCCCC12OCCO2,,ClCCl,,O=C(Cl)C(=O)Cl,c1ccncc1,test
US04614702,BrCCCOc1ccccc1.NC(N)=S>>SCCCOc1ccccc1,,CCO,CO,Cl,[K+].[OH-],test
US20110312965A1,CC(C)(C)OC(=O)/C=C/c1ccc(-c2ccc(O)c(C34CC5CC(CC(C5)C3)C4)c2)cc1.CCCCC/C=C\C/C=C\CCCCCCCC(=O)Cl>>CCCCCC=CC/C=C/CCCCCCCC(=O)Oc1ccc(-c2ccc(C=CC(=O)OC(C)(C)C)cc2)cc1C12CC3CC(CC(C3)C1)C2,,c1ccncc1,,CCOC(C)=O,,test
US20130231604A1,CC(=O)C(C)CCCCCC(=O)O.NNc1cc(I)c(I)c(I)c1>>CC1=Nc2cc(I)c(I)c(I)c2C1(C)CCCCCC(=O)O,,CC(=O)O,,,,test
US20050182058A1,CC(C)(C)OC(=O)N1CC[C@@H](N=[N+]=[N-])[C@H](O)C1.CI>>CO[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@H]1N=[N+]=[N-],,C1CCOC1,,[H-].[Na+],,test
US20050143452A1,COc1cccc(-c2cccc3c2OC(CNC(=O)OCc2ccccc2)C3)c1>>COc1cccc(-c2cccc3c2OC(CN)C3)c1,[Pd],,,,,test
US20140288040A1,COc1c(F)ccc(C#N)c1F>>N#Cc1ccc(F)c(O)c1F,,ClCCl,,BrB(Br)Br,O,test
US20100150831A1,CC(C)(C)OC(=O)N1CCCNCC1.CC(C)c1cc(Br)c2ncccc2c1>>CC(C)c1cc(N2CCCN(C(=O)OC(C)(C)C)CC2)c2ncccc2c1,,COCCOC,,CCOC(C)=O,CC(C)(C)[O-].[K+],test
US20060040918A1,Ic1ccccc1.Oc1ccc2c(c1)CCN(C1CCC1)CC2>>c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)cc1,[Cu]Br,c1ccncc1,,[H-].[Na+],,test
US20130190309A1,O=C1c2c(cccc2[N+](=O)[O-])CCN1c1cccc(C(F)(F)F)c1>>Nc1cccc2c1C(=O)N(c1cccc(C(F)(F)F)c1)CC2,[Pd],CCOC(C)=O,,[H][H],,test
US20150191465A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@H](N)c1nc2ccn(C)c2cc1N1CCC(O)C1>>C[C@H](NC(=O)OC(C)(C)C)c1nc2ccn(C)c2cc1N1CCC(O)C1,,C1CCOC1,,,,test
US05558971,C1COCCO1.C=Cc1ccc(C)cc1.C=Cc1ccc(O)cc1>>C=COCC.C=Cc1ccc(C)cc1.C=Cc1ccc(O)cc1,,C1COCCO1,,,,test
US20140343103A1,CC1(C)OB(c2cnn(CCO[Si](C)(C)C(C)(C)C)c2)OC1(C)C.O=C(Nc1cc(F)c(Oc2ccnc(Cl)c2)cc1F)c1cccn(-c2ccc(F)cc2)c1=O>>CC(C)(C)[Si](C)(C)OCCn1cc(-c2cc(Oc3cc(F)c(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)ccn2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20120059014A1,CC(C)(C)OC(=O)N[C@@H]1CNC[C@H]1c1ccc(F)cc1F.CC(C)OC(=O)N1CCC([C@H](C)CCOc2cnc(Cl)nc2)CC1>>CC(C)OC(=O)N1CCC([C@H](C)CCOc2cnc(N3C[C@@H](NC(=O)OC(C)(C)C)[C@H](c4ccc(F)cc4F)C3)nc2)CC1,,CS(C)=O,,C1CCC2=NCCCN2CC1,,test
US20110118236A1,CC(C)(C)OC(=O)N1CCC2C(C(F)(F)F)=NNC2(O)C1.CCN(CC)C(=O)c1ccc(CBr)cc1>>CCN(CC)C(=O)c1ccc(Cn2nc(C(F)(F)F)c3c2CN(C(=O)OC(C)(C)C)CC3)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090156594A1,Cn1cc(C(=O)O)cn1.NNC(N)=S>>Cn1cc(-c2nnc(N)s2)cn1,,O=P(Cl)(Cl)Cl,,,,test
US04670447,BrCCc1ccccc1.Fc1ccc2c(C3CCNCC3)n[nH]c2c1>>Fc1ccc2c(C3CCN(CCc4ccccc4)CC3)n[nH]c2c1,,O,,CN(C)C=O,O=C([O-])O.[Na+],test
US06867206B1,O=C1CCC(c2ccc(C(=O)O)cc2)=NN1.O=S(Cl)Cl>>O=C1CCC(c2ccc(C(=O)Cl)cc2)=NN1,,ClCCl,,,,test
US20110009443A1,CC(=O)C=NNC(C)(C)C.O=CC=O>>CC(=O)c1nn(C(C)(C)C)cc1O,,O,,,,test
US20100112476A1,CN.NC(=O)[O-].O=C1CC(=O)C2=C(C=NOC2)N1>>CNC(=O)c1cccnc1N,,C1COCCO1,CCO,O=C=O,,test
US20120270868A1,N#Cc1ccc(C(=O)NN)cc1.O=C(O)Cc1cccc(I)c1>>N#Cc1ccc(C(=O)NNC(=O)Cc2cccc(I)c2)cc1,,CC(=O)N(C)C,O,CCN(C(C)C)C(C)C,,test
US20050282858A1,CC(C)(C)OC(=O)N1CCC(=O)C1.CC(C)=CCBr>>C=CC(C)(C)C1(O)CCN(C(=O)OC(C)(C)C)C1,[Zn],,,C1CCOC1,[Cl-].[NH4+],test
US20150315172A1,CCOC(=O)CC(=O)CC(=O)OCC.CCOC(OCC)OCC.CN>>CCOC(=O)c1cn(C)c(=O)cc1O,,O,,CC(=O)OC(C)=O,,test
US20020156054A1,C#C[Si](C)(C)C.CC1(C)CCC(=O)c2cc(Br)ccc21>>CC1(C)CCC(=O)c2cc(C#C[Si](C)(C)C)ccc21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCN(CC)CC,,,,test
US20070027163A1,Cc1cc2ccc(Cl)cc2[nH]1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>Cc1[nH]c2cc(Cl)ccc2c1C(=O)C(F)(F)F,,ClCCCl,,,,test
US20080153887A1,C#CCO[Si](C)(C)C(C)(C)C.CON(C)C(=O)c1ccccc1>>CC(C)(C)[Si](C)(C)OCC#CC(=O)c1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US05854245,CC(C)(C)OC(=O)CBr.CC(C)(C)OC(=O)N1CCN(c2ccc(NC(=O)c3ccc(O)cc3)cc2)CC1>>CC(C)(C)OC(=O)COc1ccc(C(=O)Nc2ccc(N3CCN(C(=O)OC(C)(C)C)CC3)cc2)cc1,,CCOC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05882628,O=C(NCC(O)CO)c1cc(CO)cc([N+](=O)[O-])c1>>Nc1cc(CO)cc(C(=O)NCC(O)CO)c1,[Pd],CO,,,,test
US20120238541A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccccc4)oc4c(Cl)nccc4c3=O)cc2)CCC1.OCCO>>CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4ccccc4)oc4c(OCCO)nccc4c3=O)cc2)CCC1,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20040023964A1,CC1(C)OB(c2ccc(F)c(-c3cccnc3)c2)OC1(C)C.FC(F)(F)c1cnn2c(Br)cnc2n1>>Fc1ccc(-c2cnc3nc(C(F)(F)F)cnn23)cc1-c1cccnc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20130231327A1,CCN(C(C)C)C(C)C.ClCCl.On1nnc2ccccc21>>c1ccc2c(c1)CCC2,,ClCCl,,CCN=C=NCCCN(C)C,,test
US20080255133A1,COC(=O)c1cc2c(C)noc2c(F)c1Nc1ccccc1F.O=C1CCC(=O)N1I>>COC(=O)c1cc2c(C)noc2c(F)c1Nc1ccc(I)cc1F,,CN(C)C=O,,O=C(O)C(F)(F)F,,test
US20070054916A1,Cc1ccccc1B(O)O.Nc1ncc2cc(Cl)cnc2n1>>Cc1ccccc1-c1cnc2nc(N)ncc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,[Cs+].[F-],test
US20070244136A1,C=CCNC.C[C@@H]1CO1>>C=CCN(C)C[C@@H](C)O,,C1COCCO1,,O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3],,test
US20080064681A1,C[C@H]1CN(C(=O)OC(C)(C)C)CCCN1S(=O)(=O)c1cccc2cncc(Cl)c12.Cl.ClC(Cl)Cl>>C[C@H]1CNCCCN1S(=O)(=O)c1cccc2cncc(Cl)c12.Cl.Cl,,ClC(Cl)Cl,,C1COCCO1,,test
US20070043080A1,CC(C)C(=O)Nc1cccc(C2CCN(CCCCN)CC2)c1.COc1ccc(C(=O)Cl)cc1OC>>COc1ccc(C(=O)NCCCCN2CCC(c3cccc(NC(=O)C(C)C)c3)CC2)cc1OC,,C1CCOC1,ClCCl,,,test
US05071999,C=CCN(CC=O)C(=O)OCC.O=C(O)[C@@H]1C[C@@H](O)CN1>>CCOC(=O)N1CC2CC3CC(O)CN3C2C1,,CN(C)C=O,,,,test
US20050032871A1,CN(C)C=O.Cc1[nH]cc(CCC(=O)O)c1S(C)(=O)=O>>Cc1[nH]c(C=O)c(CCC(=O)O)c1S(C)(=O)=O,,ClCCl,,O=P(Cl)(Cl)Cl,,test
US20100022544A1,CC(C)(C)OC(=O)N1CCC(c2c(C#N)c(N)nc(SCc3csc(Nc4ccc(F)cc4)n3)c2C#N)CC1>>N#Cc1c(N)nc(SCc2csc(Nc3ccc(F)cc3)n2)c(C#N)c1C1CCNCC1,,C1COCCO1,,Cl,,test
US20160244448A1,CCOC(=O)CC(=O)N(Cc1cnc(Cl)cc1Cl)c1c(F)c(OC)cc(OC)c1F>>CCOC(=O)C1C(=O)N(c2c(F)c(OC)cc(OC)c2F)Cc2cnc(Cl)cc21,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20050256198A1,CCN(Cc1ccccc1F)C(=O)Cc1ccc(OCc2ccccc2C(=O)OC)cc1>>CCN(Cc1ccccc1F)C(=O)Cc1ccc(OCc2ccccc2C(=O)O)cc1,,CCO,,[K+].[OH-],,test
US20070244131A1,COc1nc(Cl)cc(Cl)n1.NCCc1ccc(F)c(F)c1>>COc1nc(Cl)cc(NCCc2ccc(F)c(F)c2)n1,,CCO,,O,O=C([O-])O.[Na+],test
US04971982,O=C(O)c1ccc(I)nc1.OCc1ccccc1>>O=C(OCc1ccccc1)c1ccc(I)nc1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04159331,CCCc1ccc(S(=O)(=O)N2CCNCC2)cc1F.O=[N+]([O-])c1ccc(S(=O)(=O)Cl)cc1>>CCCc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc([N+](=O)[O-])cc3)CC2)cc1F,,CCN(CC)CC,,,,test
US20070208062A1,CN(CCOC[C@@H]1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1)CC(=O)OC(C)(C)C>>CN(CCOC[C@@H]1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1)CC(=O)O,,O=C(O)C(F)(F)F,,,,test
US20100144751A1,CCOC(=O)C1CN(Cc2ccccc2)CC(F)(F)C1=O>>OC1(O)CCN(Cc2ccccc2)CC1(F)F,,Cl,,O=C([O-])O.[Na+],,test
US20130029964A1,BrCCOC1CCCCO1.Oc1ccc(Br)cc1>>Brc1ccc(OCCOC2CCCCO2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04313949,CC(C)(C)OCl.CCCCC(N)=S.Nc1ccccc1C(=O)c1ccc(F)cc1>>CCCSC(C(N)=O)c1cccc(C(=O)c2ccc(F)cc2)c1N,,ClCCl,,CCN(CC)CC,,test
US04596873,COC(COC(=O)C1=C(C)NC2=C(C(=O)CN(Cc3ccccc3)C2)C1c1cccc(Cl)c1)c1ccccc1>>COC(COC(=O)C1=C(C)NC2=C(C(=O)CNC2)C1c1cccc(Cl)c1)c1ccccc1,[Pd],CO,,Cl,[H][H],test
US20150210697A1,COc1ccc(CN(c2nc(Nc3cc(C#N)cc(N4CCC(N(C)C5CC(=O)N(C)C5)CC4)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1>>CN1CC(N(C)C2CCN(c3cc(C#N)cc(Nc4nc(NC5CC5)c5ncc(C#N)n5n4)c3Cl)CC2)CC1=O,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US20160115125A1,Cn1cc(S(=O)(=O)Cl)cc1C(=O)[O-].Cn1cc(S(=O)(=O)NC2(C)COC2)cc1C(=O)O.NCC(F)F>>COC(=O)c1cc(S(=O)(=O)NCC(F)F)cn1C,,CC#N,,CCN(C(C)C)C(C)C,,test
US04004009,CN(N)c1cnn(-c2cccc(C(F)(F)F)c2)c(=O)c1.COC(OC)N(C)C>>Cn1ncc2nn(-c3cccc(C(F)(F)F)c3)c(=O)cc21,,CN(C)C=O,,,,test
US20030013713A1,COc1ccc(C=O)cc1OC1CCCC1.Nc1ccccc1Cl>>COc1ccc(CNc2ccccc2Cl)cc1OC1CCCC1,,Cc1ccccc1,,O,,test
US05532267,COC(=O)Cc1ccc(C(=O)NCc2ccc(C(=O)Oc3ccc4cc(C(=N)N)ccc4c3)o2)cc1.Cl>>Cl.N=C(N)c1ccc2cc(OC(=O)c3ccc(CNC(=O)c4ccc(CC(=O)O)cc4)o3)ccc2c1,,CC(=O)O,,Cl,,test
US20110301155A1,CCOC(=O)CC(Br)C=O.NC(=S)Nc1n[nH]c2c(OCCc3ccccn3)cc(-c3ncccc3Cl)cc12>>CCOC(=O)Cc1cnc(Nc2n[nH]c3c(OCCc4ccccn4)cc(-c4ncccc4Cl)cc23)s1,,C1CCOC1,CCO,O=C([O-])O.[Na+],,test
US20080293782A1,C=CCCCCBr.CCOC(=O)C(C)C>>C=CCCCCC(C)(C)C(=O)OCC,,C1CCOC1,CCOC(C)=O,O,CC(C)[N-]C(C)C.[Li+],test
US20130019348A1,O=C(NC(=S)Nc1ccccc1C1CC1)c1ccccc1>>NC(=S)Nc1ccccc1C1CC1,,CO,,Cl,[Na+].[OH-],test
US20070208001A1,CNC(=O)c1ccc(-c2ccc(C3(O)CCC(C(=O)N[C@@H]4CC[C@H](O)CC4)CC3)c(C)c2)cc1>>CNC(=O)c1ccc(-c2ccc(C3=CCC(C(=O)N[C@@H]4CC[C@H](O)CC4)CC3)c(C)c2)cc1,,C1COCCO1,,Cl,,test
US20030199566A1,COC(=O)C(NC(=O)CCc1ccc(O)cc1)C(C)C>>CC(C)C(NC(=O)CCc1ccc(O)cc1)C(=O)O,,C1CCOC1,,Cl,[Li+].[OH-],test
US20110124877A1,COC(=O)C1CCC2(CC2)O1.Fc1ccc(CBr)cc1>>O=C1C(Cc2ccc(F)cc2)CCC12CC2,,CCCCCC,CN(C)C=O,O,[H-].[Na+],test
US05508430,Cc1ccc(S(=O)(=O)OC[C@@H](O)[C@H](Cc2ccccc2)N=[N+]=[N-])cc1>>[N-]=[N+]=N[C@@H](Cc1ccccc1)[C@H]1CO1,,CCO,,[K+].[OH-],,test
US20160152577A1,CC(=O)O.CCCCOC(=O)OC(=O)[O-].CCN(CC)CC.OCC1CCNCC1>>CC(C)(C)OC(=O)N1CCC(CO)CC1,,ClCCl,,,,test
US20130035339A1,CC(=O)O.NC1CC1.NNC(=O)c1cccc(NC(=O)c2cc(Cl)ccn2)n1>>O=C(Nc1cccc(-c2nncn2C2CC2)n1)c1cc(Cl)ccn1,,Cc1ccccc1,,,,test
US20090181939A1,C1CCOC1.CC(C)[Mg]Cl.Clc1ccc(I)cn1.O>>OC(c1ccc(Cl)nc1)c1ccccc1Cl,,C1CCOC1,,[Cl-].[Na+],,test
US04010177,C=CCN.ClCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2>>C=CCNCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2,,C1CCOC1,,[I-].[K+],,test
US04855301,CC1=C(C(=O)OC(C)C)C(c2cccc([N+](=O)[O-])c2)N(C(=O)N(C)C)C(=O)N1.CS(C)=O>>CC1=C(C(=O)OC(C)C)C(c2cccc([N+](=O)[O-])c2)NC(=S)N1,,CO,,Cl,C[O-].[Na+],test
US20050065066A1,O=C1CSC(=O)N1.O=Cc1ccc(OCCCCCC(C(=O)O)C(=O)O)c2ccccc12>>O=C1NC(=O)C(=Cc2ccc(OCCCCCC(C(=O)O)C(=O)O)c3ccccc23)S1,,CC(=O)O,,C1CCNCC1,,test
US07192967B1,O=C(C=Cc1cccnc1)NCCCCO.O=C1CC(c2ccccc2)CC(=O)N1>>O=C(C=Cc1cccnc1)NCCCCN1C(=O)CC(c2ccccc2)CC1=O,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070185143A1,CSC(=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C.N>>CC(C)(C)OC(=O)NC(=N)NC(=O)OC(C)(C)C,,CO,,,,test
US20090286813A1,N#Cc1cccc(-n2c(N)c(N)c(=O)[nH]c2=S)c1.N=CN>>N#Cc1cccc(-n2c(=S)[nH]c(=O)c3[nH]cnc32)c1,,CS(C)=O,,CC(=O)O,,test
US04866077,CC(=O)CN.O=C(Cl)c1cccnc1>>CC(=O)CNC(=O)c1cccnc1,,ClCCl,,,,test
US20160185785A1,Ic1ccccc1.O=[N+]([O-])c1cn[nH]c1>>O=[N+]([O-])c1cnn(-c2ccccc2)c1,[Cu]I,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120035168A1,CCOC(=O)c1cn(Cc2ccc(CO)cc2)nn1>>O=C(O)c1cn(Cc2ccc(CO)cc2)nn1,,CO,O,[Li+].[OH-],,test
US20080227791A1,Clc1ccc(Cl)nn1.NC1CCN(Cc2ccc(Cl)cc2)CC1>>Clc1ccc(CN2CCC(Nc3ccc(Cl)nn3)CC2)cc1,,CC(=O)N(C)C,O,O=C([O-])[O-].[Na+].[Na+],,test
US06114391,CI.NC(=O)CNC1Cc2ccccc2C1>>CN(CC(N)=O)C1Cc2ccccc2C1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20070066573A1,O.O=C1c2ccccc2-c2ccc(I)cc21>>O=C(O)c1ccccc1-c1ccc(I)cc1,,COCCOC,ClCCl,Cl,CC(C)(C)[O-].[K+],test
US20100160424A1,Clc1cccc(Br)c1.O=Cc1cccc(Br)c1>>OC(c1cccc(Cl)c1)c1cccc(Br)c1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20140221345A1,CCOC(=O)COc1cccc2ccc(N3CCOCC3)nc12.NCC(O)CN1CCc2ccccc2C1>>O=C(COc1cccc2ccc(N3CCOCC3)nc12)NCC(O)CN1CCc2ccccc2C1,,CCO,,,,test
US20060194857A1,CN(C)S(=O)(=O)Cl.c1c[nH]nn1>>CN(C)S(=O)(=O)n1cncn1,,Cc1ccccc1,,CCN(CC)CC,,test
US20100105719A1,CCCCCCN=C=O.O=C1NC(=O)N2CCCCC12>>CCCCC(C)C(N)=O.O=C1NC(=O)N2CCCCC12,,C1COCCO1,,,,test
US20110152257A1,COC(=O)c1c(C(C)(C)C)nn2cc(Br)ccc12>>CC(C)(C)c1cc2ccc(Br)cn2n1,,O,O=S(=O)(O)O,[Na+].[OH-],,test
US20150133422A1,BrCCBr.O=S(=O)(c1ccccc1)n1cc(-c2cn[nH]c2)c2ccc(F)cc21>>O=S(=O)(c1ccccc1)n1cc(-c2cnn(CCBr)c2)c2ccc(F)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20040072827A1,CC(C)(C)OC(=O)NCCCn1c(-c2ccc(Br)cc2)csc1=Nc1ccccc1.CI>>CN(CCCn1c(-c2ccc(Br)cc2)csc1=Nc1ccccc1)C(=O)OC(C)(C)C,,CN(C)C=O,,O,[H-].[Na+],test
US05180741,CC(=O)OC(C)=O.N#Cc1cccc2c1CCC2O>>CC(=O)OC1CCc2c(C#N)cccc21,,c1ccncc1,,O,[Cl-].[Na+],test
US20030166639A1,CC(C)(C)OC(=O)Nc1cc(Cl)c(C(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-c2cnccn2)c1>>O=C1CC(c2cccc(-c3cnccn3)c2)=Nc2cc(Cl)c(C(F)(F)F)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130137700A1,ClCCN1CCn2c1nc1ccccc12.O=c1c(O)cn(CC2CC2)nc1-c1ccnn1-c1ccccc1>>O=c1c(OCCN2CCn3c2nc2ccccc23)cn(CC2CC2)nc1-c1ccnn1-c1ccccc1,,CC(=O)N(C)C,,[I-].[Na+],O=C([O-])[O-].[Cs+].[Cs+],test
US20080176829A1,CN1CCOc2ccc3c(ccn3S(=O)(=O)c3ccccc3)c2C1.COC(=O)C1CC1>>CN1CCOc2ccc3c(cc(C(O)C4CC4)n3S(=O)(=O)c3ccccc3)c2C1,,C1CCOC1,,[Li]CCCC,,test
US20080131751A1,CCc1ncc[nH]1.O=S(=O)(O)C(F)(F)F>>CCc1[nH]cc[nH+]1.O=S(=O)([O-])C(F)(F)F,,O,,,,test
US05135937,N#Cc1ccc(C(c2ncc[nH]2)C2(O)CCCC2)cc1>>N#Cc1ccc(C(=C2CCCC2)c2ncc[nH]2)cc1,,O=S(Cl)Cl,,,,test
US04672068,CCOC(=O)C1=C(C)NC(C)=C(C(=O)O)C1c1cccc([N+](=O)[O-])c1.OCC=CC=Cc1ccccc1>>CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC=CC=Cc2ccccc2)C1c1cccc([N+](=O)[O-])c1,CN(C)c1ccncc1,CC(Cl)Cl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20160143895A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c([C@@H]3CCCNC3)cc12.Cc1c(C(=O)O)[nH]c2c(F)cccc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c([C@@H]3CCCN(C(=O)c4[nH]c5c(F)cccc5c4C)C3)cc12,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,CCN=C=NCCCN(C)C,test
US20120004203A1,CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)c2nc(N3C(=O)c4ccccc4C3=O)nn2C1c1ccc(C#N)cc1.O>>CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)c2nc(NC(=O)c3ccccc3C(=O)O)nn2C1c1ccc(C#N)cc1,,CCO,,Cl,O=C([O-])[O-].[K+].[K+],test
US04742075,CC(=O)C1CN(C)C2Cc3cn(S(=O)(=O)c4ccccc4)c4cccc(c34)C12>>CC(=O)C1CN(C)C2Cc3c[nH]c4cccc(c34)C12,,CCO,,[K+].[OH-],,test
US20090156642A1,CN(CC(N)=S)C(=O)OC(C)(C)C.O=C(CBr)c1cccnc1F>>CN(Cc1nc(-c2cccnc2F)cs1)C(=O)OC(C)(C)C,,CN(C)C=O,,Br,O=C([O-])O.[Na+],test
US20100298140A1,CC12CCC(O1)C1C(=O)CC(=O)C12.ClP(Cl)(Cl)(Cl)Cl>>CC12CCC(O1)C1C(Cl)=CC(=O)C12,,ClC(Cl)Cl,,,,test
US20050234096A1,CCOC(=O)CBr.Cc1cccc(O)c1>>CCOC(=O)COc1cccc(C)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06248755B1,CCC(CC)C(O)C(=O)O.COc1ccc(CCl)cc1>>CCC(CC)C(O)C(=O)OCc1ccc(OC)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100056530A1,CSc1cnc(Nc2nc(C)cs2)c(OCc2ccccc2)c1.Cl.O=C(OO)c1cccc(Cl)c1>>Cc1csc(Nc2ncc(S(C)=O)cc2OCc2ccccc2)n1.Cl,,CCOCC,ClCCl,,,test
US04906643,COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(CCCCN(C)C(=O)OC(C)(C)C)C[C@H]1OC>>CNCCCCN1CC[C@H](NC(=O)c2cc(Cl)c(N)cc2OC)[C@H](OC)C1,,CC(C)O,,Cl,,test
US20100137299A1,O=C1N(C(c2ccccc2)c2ccccc2)c2ccccc2C12COc1cc3c(cc12)CCCO3>>O=C1Nc2ccccc2C12COc1cc3c(cc12)CCCO3,,O,O=C(O)C(F)(F)F,CC[SiH](CC)CC,,test
US20100105705A1,Cn1cnc2c(Cl)nc(-c3ccccn3)nc21.Nc1ccc(Cl)cc1>>Cn1cnc2c(Nc3ccc(Cl)cc3)nc(-c3ccccn3)nc21,,CC#N,,CCN(C(C)C)C(C)C,,test
US20080009486A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.Cc1ccc(F)c(F)c1C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12>>Cc1ccc(F)c(F)c1C1NC(=S)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12,,Cc1ccccc1,,,,test
US20160251339A1,COc1ccc(S(=O)(=O)n2cc(C(F)F)c3ccc(Cl)cc32)cc1N1CCN(C(=O)C(Cl)(Cl)Cl)CC1>>COc1ccc(S(=O)(=O)n2cc(C(F)F)c3ccc(Cl)cc32)cc1N1CCNCC1,,C1CCOC1,,[K+].[OH-],,test
US20120058984A1,CS(=O)(=O)c1nccc(Nc2nc3ccc(Br)cc3s2)n1.N[C@H]1CC[C@H](O)CC1>>O[C@@H]1CC[C@@H](Nc2nccc(Nc3nc4ccc(Br)cc4s3)n2)CC1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US06245746B1,CC(C)(C)OC(=O)NCCC[C@H](N)C(=O)O.O=Cc1ccccc1>>CC(C)(C)OC(=O)NCCC[C@H](NCc1ccccc1)C(=O)O,,CO,O,[Na+].[OH-],,test
US04075165,C1CO1.CCC1(C)CC(OC(=O)NC)C(C)C(C)(CC)N1>>CCC1(C)CC(OC(=O)NC)C(C)C(C)(CC)N1CCO,Cl,CO,,,,test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2cc(-c3cc([C@@H](C)N4CCN(C(=O)OC(C)(C)C)CC4)cnc3F)nc(C)n2)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2cc(-c3cc([C@@H](C)N4CCNCC4)cnc3F)nc(C)n2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05753664,CCc1c(C)nc2n(Cc3ccc(C(=O)c4ccc(O)cc4)cc3)ccn2c1=O.Cl.ClCCN1CCOCC1>>CCc1c(C)nc2n(Cc3ccc(C(=O)c4ccc(OCCN5CCOCC5)cc4)cc3)ccn2c1=O.Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040058964A1,Cc1cc(O)c(Cl)c(=O)n1-c1c(F)cccc1F.Fc1ccc(CBr)c(F)c1>>Cc1cc(OCc2ccc(F)cc2F)c(Cl)c(=O)n1-c1c(F)cccc1F,,CC(=O)N(C)C,O,O=C([O-])[O-].[K+].[K+],,test
US20080176833A1,CC1=C(C#N)C(c2ccc3c(c2)c(N)nn3C(=O)OC(C)(C)C)C(C#N)=C(C)N1.CC=O>>CCNc1nn(C(=O)OC(C)(C)C)c2ccc(C3C(C#N)=C(C)NC(C)=C3C#N)cc12,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20040127574A1,Cc1cccc(O)c1.FC(F)(F)CI>>Cc1cccc(OCC(F)(F)F)c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20100041628A1,CCI.NC(=O)c1c(N)[nH]c2ccccc12>>CCn1c(N)c(C(N)=O)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20130131132A1,C[Si](C)(C)C#N.NC1CCc2ccc(CNS(=O)(=O)C3CCC3)cc2C1Cc1ccccc1.O=C1COC1>>N#CC1(NC2CCc3ccc(CNS(=O)(=O)C4CCC4)cc3C2Cc2ccccc2)COC1,,CCOC(C)=O,,,,test
US20080280864A1,CC(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@@H]3[C@@H]2CC[C@]2(C)C(n4cnc5ccccc54)=CC[C@@H]32)C1>>C[C@]12CC[C@H](O)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(n3cnc4ccccc43)=CC[C@@H]12,,CO,,[K+].[OH-],,test
US20110118234A1,N#CC1(c2ccnc(Cl)c2)CCCC1.O=C([O-])O>>O=C(O)C1(c2ccnc(Cl)c2)CCCC1,,Cl,,O,,test
US04891365,C[C@]12CCC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1[C@@H](O)CC2=O.O=C(Cl)c1ccccc1>>C[C@]12CCC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1[C@@H](OC(=O)c1ccccc1)CC2=O,,c1ccncc1,,,,test
US20070032485A1,C1COCCN1.CCOC(=O)N1c2ccc(OC)nc2[C@@H](Nc2ncc(CBr)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC>>CCOC(=O)N1c2ccc(OC)nc2[C@@H](Nc2ncc(CN3CCOCC3)c(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)n2)C[C@H]1CC,,CN(C)C=O,,[H-].[Na+],,test
US20050113411A1,CC(C)(C)[Si](C)(C)O[C@@H](CBr)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12.NCCc1ccc(NC[C@@H](O)c2ccccc2)cc1>>CC(C)(C)[Si](C)(C)O[C@@H](CNCCc1ccc(NC[C@@H](O)c2ccccc2)cc1)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12,,CS(C)=O,,,,test
US20110118234A1,CC(C)(N)c1ccc2occc2c1.Cc1cc(-c2ccc(N)cc2)ccn1.O=C(n1ccnc1)n1ccnc1>>Cc1cc(-c2ccc(NC(=O)NC(C)(C)c3ccc4occc4c3)cc2)ccn1,,O=C([O-])O,[Na+],CCN(CC)CC,,test
US20050215797A1,Cc1c(C(F)(F)F)nn(C)c1O.FC(F)Cl>>Cc1c(C(F)(F)F)nn(C)c1OC(F)F,,CC(C)O,,O,[K+].[OH-],test
US05605914,COc1ccc(C(N)CC(=O)O)cc1.O=C1OC(=O)C2(Cl)C(Cl)=C(Cl)C(Cl)=CC12>>COc1ccc(C(CC(=O)O)N2C(=O)C3C=C(Cl)C(Cl)=C(Cl)C3(Cl)C2=O)cc1,,CC(=O)O,,,,test
US04939159,C=C(C)n1c(C)c(-c2ccc(F)cc2)c2cccnc21>>Cc1c(-c2ccc(F)cc2)c2cccnc2n1C(C)C,[Pd],CCOC(C)=O,,CCO,[H][H],test
US20150080396A1,CCCCCNc1nc(N)nc(C)c1Cc1ccc(OCCCO)cc1.O=S(Cl)Cl>>CCCCCNc1nc(N)nc(C)c1Cc1ccc(OCCCCl)cc1,,O=S(Cl)Cl,,ClCCl,,test
US20080292626A1,CC(C)Cc1nc2n(c(=O)c1Cc1ccccc1)Cc1ccccc1-2.O=C1CCC(=O)N1Br>>CC(C)C(Br)c1nc2n(c(=O)c1Cc1ccccc1)Cc1ccccc1-2,,CC#N,ClCCl,O=C(O)C(F)(F)F,,test
US20110015175A1,CCOC(=O)Cl.Oc1cccc(F)c1F>>CCOC(=O)Oc1cccc(F)c1F,,CCOC(C)=O,,CCN(CC)CC,Cl,test
US20060030595A1,N#CCc1ccc(F)cc1.[N-]=[N+]=[N-]>>Fc1ccc(Cc2nn[nH]n2)cc1,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US04374843,CCOC(=O)c1csc(NC(=N)N)n1.NN>>N=C(N)Nc1nc(C(=O)NN)cs1,,CCO,,O,,test
US20150299121A1,C=C1CC(C(=O)O)C1.OCc1ccccc1>>C=C1CC(C(=O)OCc2ccccc2)C1,,CCOC(C)=O,,O=C(n1ccnc1)n1ccnc1,,test
US20080045526A1,CCN(CC)CCc1ccc2c(n1)COC2=O.O=C1Cc2cc(F)ccc2N1>>CCN(CC)Cc1ccc2c(n1)COC2=C1C(=O)Nc2ccc(F)cc21,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20030225097A1,N#CCC1CCCN(C(=O)OCc2ccccc2)C1>>N#CCC1CCCNC1,[Pd],CCO,,Cl,,test
US05530138,O=C(O)/C=C\C(=O)O.O=[N+]([O-])c1ccccc1NCCC12CCCN1CCC2>>O=C(O)/C=C\C(=O)O.O=[N+]([O-])c1ccccc1NCCC12CCCN1CCC2,,CCO,,,,test
US20110301162A1,CSCC=O.Nc1cc(Cl)ccn1>>CSCCNc1cc(Cl)ccn1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160083368A1,CCOC(=O)Cn1nc(C#N)c2c1C(O)[C@@H]1C[C@H]21>>CCOC(=O)Cn1nc(C#N)c2c1C(=O)[C@@H]1C[C@H]21,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20080146542A1,CN(N=C(c1ccccc1)c1ccccc1)c1ccc(Cl)cc1>>CN(N)c1ccc(Cl)cc1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20090176786A1,CN(C(=O)Cl)c1ccc(SC(F)(F)F)cc1F.NCCOc1ccccc1>>CN(C(=O)NCCOc1ccccc1)c1ccc(SC(F)(F)F)cc1F,,COC(C)(C)C,,CCN(CC)CC,,test
US20120108696A1,C(=NC1CCCCC1)=NC1CCCCC1.ON=C1CCCCC1>>C1CCC(=NOC(=NC2CCCCC2)NC2CCCCC2)CC1,,C1CCOC1,ClCCl,[Na+].[OH-],,test
US20080064699A1,C[Si](C)(C)CCOCn1cc(-c2ccc(F)cc2F)s/c1=N\C(=O)C12CC3CC(CC(C3)C1)C2>>O=C(Nc1ncc(-c2ccc(F)cc2F)s1)C12CC3CC(CC(C3)C1)C2,,O=C(O)C(F)(F)F,,,,test
US04111923,CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)OCc1ccccc1.Cl>>CCNC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCNC(=N)N.Cl,[Pd],O,,CO,[H][H],test
US20110294854A1,Br[Mg]c1ccccc1.O=C1CC[C@@H]2CN(c3cccc(C(F)(F)F)n3)C[C@H]12>>O[C@]1(c2ccccc2)CC[C@@H]2CN(c3cccc(C(F)(F)F)n3)C[C@@H]21,,C1CCOC1,,,,test
US20150344485A1,OC1CCCC1.Oc1c(F)cc(Br)cc1F>>Fc1cc(Br)cc(F)c1OC1CCCC1,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070082912A1,COC(=O)c1cc([N+](=O)[O-])ccc1OC(F)F>>COC(=O)c1cc(N)ccc1OC(F)F,[Pd],CO,,,,test
US20040006226A1,C1CCNC1.O=C1CCc2ccccc21>>C1=C(N2CCCC2)c2ccccc2C1,Cl[Ti](Cl)(Cl)Cl,CCCCC,,,,test
US04897405,Cc1cc2ccccc2cc1C(=O)O>>Cc1cc2ccccc2cc1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20020193596A1,C1CCOC1.COC(=O)[C@H](CCSC)NC(=O)c1ccc(CN=[N+]=[N-])cc1-c1ccccc1.O>>CCOC(C)=O.COC(=O)[C@H](CCSC)NC(=O)c1ccc(CN)cc1-c1ccccc1.N,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20080207654A1,CCCc1nc(CC)n(-c2ccc3c(c2)CC(C)(C)O3)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCc1nc(CC)n(-c2ccc3c(c2)CC(C)(C)O3)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US06440965B1,CCO.CN1CCNCC1.Clc1ncc(Cc2ccccc2)c(Cl)n1>>Cc1ccc(Cc2cnc(Cl)nc2N2CCN(C)CC2)cc1,,CCO,,CCN(CC)CC,,test
US20150005282A1,COC(=O)C[C@@H]1COc2cc(O)ccc21.Cc1cc(O[Si](C)(C)C(C)(C)C)cc(C)c1-c1cccc(CO)c1>>COC(=O)C[C@@H]1COc2cc(OCc3cccc(-c4c(C)cc(O[Si](C)(C)C(C)(C)C)cc4C)c3)ccc21,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060030600A1,Cc1cc(F)ccc1-c1cc(C2=CCN(C(=O)OC(C)(C)C)CC2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>Cc1cc(F)ccc1-c1cc(C2=CCNCC2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20070191420A1,N#Cc1ccc(C(=O)O)cc1.Nc1ccncc1>>N#Cc1ccc(C(=O)Nc2ccncc2)cc1,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20060223801A1,CCOC(=O)c1ccc(C)[nH]1.COC(OC)OC>>CCOC(=O)c1cc(C=O)c(C)[nH]1,,O=C(O)C(F)(F)F,,,,test
US20110218193A1,CCOC(=O)CCc1ccc(N)cc1.O=C(O)c1cccnc1Cl>>CCOC(=O)CCc1ccc(NC(=O)c2cccnc2Cl)cc1,,CCN(CC)CC,ClCCl,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20120083006A1,CC(C)(C)OC(=O)NCCBr.O=[N+]([O-])c1cccc(O)c1>>CC(C)(C)OC(=O)NCCOc1cccc([N+](=O)[O-])c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04853408,CC(=O)c1ccc(OCCCl)cc1.CC(C)(C)N>>CC(=O)c1ccc(OCCNC(C)(C)C)cc1,,O,,,,test
US20100222318A1,CC(=O)Oc1ccccc1-c1nnc(-c2nc(-c3ccc(S(=O)(=O)C(C)C)cc3)cnc2N)o1>>CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3nnc(-c4ccccc4O)o3)n2)cc1,,C1CCOC1,,Cl,[Li+].[OH-],test
US20100093718A1,Brc1ccnc(OC2CCOCC2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>OB(O)c1ccnc(OC2CCOCC2)c1,,CS(C)=O,,CC(=O)[O-].[K+],,test
US20090062349A1,Cn1nnc(-c2c(F)cc(Cl)cc2-c2cnc(CNC(=O)OC(C)(C)C)c(F)c2)n1>>Cn1nnc(-c2c(F)cc(Cl)cc2-c2cnc(CN)c(F)c2)n1,,CCOC(C)=O,,,,test
US20070117840A1,CC(C)(C)Cn1c(C(=O)OC(C)(C)C)c(OS(=O)(=O)C(F)(F)F)c2cc(Cl)c(Cl)cc2c1=O.OB(O)c1ccccc1>>CC(C)(C)Cn1c(C(=O)OC(C)(C)C)c(-c2ccccc2)c2cc(Cl)c(Cl)cc2c1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US06329381B1,BrBr.Nc1nc(N)c2ncn(Cc3ccccc3)c2n1>>Nc1nc(N)c2nc(Br)n(Cc3ccccc3)c2n1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20100120669A1,CCOC(=O)CCl.Oc1ccc(Cl)cc1>>CCOC(=O)COc1ccc(Cl)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130303524A1,C=C(C)CN.O=S(=O)(Cl)CCCl>>C=CS(=O)(=O)NCC(=C)C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04062862,FC(F)(F)C=CCc1ccccc1.O=C(OO)c1ccccc1>>FC(F)(F)C=CCC1=CC=CC2OC12,,ClC(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20070265309A1,CC(C)I.O=C(c1ccc(F)cc1)N(Cc1cc(-c2ccc3c(c2)nnn3C(c2ccccc2)(c2ccccc2)c2ccccc2)ccc1F)C1CCNCC1>>CC(C)N1CCC(N(Cc2cc(-c3ccc4c(c3)nnn4C(c3ccccc3)(c3ccccc3)c3ccccc3)ccc2F)C(=O)c2ccc(F)cc2)CC1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20160002248A1,NCc1ccccn1.O=C(O)c1cn(CCCCc2cc3c(-c4ccccc4)c[nH]c3nn2)nn1>>O=C(NCc1ccccn1)c1cn(CCCCc2cc3c(-c4ccccc4)c[nH]c3nn2)nn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020165231A1,Nc1cc(F)ccc1F.O=Cc1cccc(OC(F)(F)C(F)F)c1>>Fc1ccc(F)c(NCc2cccc(OC(F)(F)C(F)F)c2)c1,,C1CCCCC1,,,,test
US20080275043A1,CCOC(=O)C(C)(C)Br.O=C1C(Cc2c(Cl)cc(-c3ccc(O)cc3)cc2Cl)CCN1C1CCCCC1>>CCOC(=O)C(C)(C)Oc1ccc(-c2cc(Cl)c(CC3CCN(C4CCCCC4)C3=O)c(Cl)c2)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090163488A1,N#CC1(c2cccc(C(=O)Nc3cccc(Oc4ccc5nc(NC(=O)C(F)(F)F)cn5c4)c3)c2)CC1>>N#CC1(c2cccc(C(=O)Nc3cccc(Oc4ccc5nc(N)cn5c4)c3)c2)CC1,,CCO,,O,[Na+].[OH-],test
US20060173050A1,CSc1ccccc1C=O>>CSc1ccccc1CO,,CCO,O,[BH4-].[Na+],,test
US20110065764A1,CCOC(=O)C(Cl)=NO.N#CCC(=O)c1ccc(C(F)(F)F)cc1>>CCOC(=O)c1noc(-c2ccc(C(F)(F)F)cc2)c1C#N,,CCO,,CCN(CC)CC,,test
US07173022B2,CC(C)(C#N)CCCCl.NO>>CC1(C)CCCN(O)C1=N,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20120088752A1,CCOC(=O)C1CCN(c2ccc(F)c(-c3nc4cc(Cl)ccc4n3C(=O)OC(C)(C)C)c2)CC1.Cl>>Cl.O=C(O)C1CCN(c2ccc(F)c(-c3nc4cc(Cl)ccc4[nH]3)c2)CC1,,Cl,,,,test
US20110294807A1,CCC(C)c1ccc(N)cc1.CS(=O)(=O)c1ccc2c(=O)oc(=O)[nH]c2c1>>CCC(C)c1ccc(NC(=O)c2ccc(S(C)(=O)=O)cc2N)cc1,,CN(C)C=O,O,,,test
US20110021537A1,CCCCOC(=O)NC1CCN(C(=O)OCc2ccccc2)C1>>CCCCOC(=O)NC1CCNC1,[Pd],CCOC(C)=O,,,,test
US05071844,COc1ccc(CCN2CCC[C@@]2(C)C(=O)O)cc1>>COc1ccc(CCN2CCC[C@@]2(C)CO)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070254873A1,NC(=O)c1cc(-c2ccc(CO)s2)cc2c(C3CCN(S(=O)(=O)CCCN4CCCC4)CC3)c[nH]c12>>NC(=O)c1cc(-c2ccc(C=O)s2)cc2c(C3CCN(S(=O)(=O)CCCN4CCCC4)CC3)c[nH]c12,O=[Mn]=O,C1CCOC1,,,,test
US20160185779A1,CNc1ccccc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.c1ccc(-c2n[nH]c3c2CNCC3)cc1>>CN(C(=O)N1CCc2[nH]nc(-c3ccccc3)c2C1)c1ccccc1,,ClCCl,,O,,test
US20050245741A1,CCOC(=O)C1(Cc2ccccc2F)CCN(Cc2ccccc2)CC1>>OCC1(Cc2ccccc2F)CCN(Cc2ccccc2)CC1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140336377A1,Cl.O=C1c2ccccc2C(=O)N1Cc1cnc(OCC(F)(F)F)c(Br)c1>>Cl.NCc1cnc(OCC(F)(F)F)c(Br)c1,,C1COCCO1,,,,test
US20030125377A1,CC(C)=CCc1c(O)cc(O)cc1-c1cc2ccc(O)cc2o1>>Oc1cc(O)cc(-c2cc3ccc(O)cc3o2)c1,,CO,,[Cl-].[Na+],,test
US20100137286A1,COC(=O)[C@@H]1CC[C@@H](Oc2ccc(F)cn2)CC1.NN>>NNC(=O)[C@@H]1CC[C@@H](Oc2ccc(F)cn2)CC1,,CCCCO,,O,,test
US20140088124A1,COC(=O)C(C)(C)COC1CCNCC1.Fc1ccc2nc(-c3ccc(F)nc3)[nH]c2c1>>COC(=O)C(C)(C)COC1CCN(c2ccc(-c3nc4cc(F)ccc4[nH]3)cn2)CC1,,CN1CCCC1=O,,O,O=C([O-])O.[Na+],test
US06046192,CC(C)(C)OC(=O)N[C@H]1CCc2ccc(O)cc2C1.CCOC(=O)CCCBr>>CCOC(=O)CCCOc1ccc2c(c1)C[C@@H](NC(=O)OC(C)(C)C)CC2,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20110152273A1,CCN1CCN(c2nc(C#N)c(C(=O)OC)c(Nc3cccc(C)c3)n2)CC1>>CCN1CCN(c2nc3c(c(Nc4cccc(C)c4)n2)C(=O)NC3)CC1,[Pd],CCO,Cl,,,test
US20110112062A1,CC(C)(C)OC(=O)N1CCCC12CCNC2.NC1C2CC3CC(C2)CC1C3.O=C(n1ccnc1)n1ccnc1>>CC(C)(C)OC(=O)N1CCCC12CCN(C(=O)NC1C3CC4CC(C3)CC1C4)C2,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110039889A1,CC(C)(C)OC(=O)CCc1nccc2c(C(=N)NO)cccc12.N#Cc1cc(C(=O)Cl)ccc1OCC1CC1>>CC(C)(C)OC(=O)CCc1nccc2c(-c3noc(-c4ccc(OCC5CC5)c(C#N)c4)n3)cccc12,,CN(C)C=O,,CCN(CC)CC,,test
US20110092485A1,CC1(C)OB(c2ccc(CC(=O)O)cc2)OC1(C)C.CCO>>CCOC(=O)Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100136136A1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.Nc1ccc(O)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(N)c([N+](=O)[O-])c2)CC1,,CC(=O)N(C)C,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04391808,CN1CCN(C2=Nc3ccccc3Sc3nccn32)CC1.Cl.O=C(OO)c1cccc(Cl)c1>>C[N+]1([O-])CCN(C2=Nc3ccccc3Sc3nccn32)CC1.Cl,,CCOCC,ClCCl,,,test
US20090023779A1,COc1cc(Cl)c(C(=O)C23CC4CC(CC(C4)C2)C3)c(OC)c1>>O=C(c1c(O)cc(O)cc1Cl)C12CC3CC(CC(C3)C1)C2,,ClCCl,,BrB(Br)Br,O,test
US20020161014A1,COc1cc2nc(CCl)n(-c3ccccc3Cl)c(=O)c2cc1OC.Sc1ncnc2nc[nH]c12>>COc1cc2nc(CSc3ncnc4[nH]cnc34)n(-c3ccccc3Cl)c(=O)c2cc1OC,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050101644A1,Fc1ccccn1.OC1CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1>>Clc1ccc(COc2ccc(Br)cc2CN2CCC(Oc3ccccn3)CC2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04010260,O=C(N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)O)OCc1ccccc1>>COC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](N)Cc1c[nH]c2ccccc12,[Pd],,,CC(=O)O,[H][H],test
US20160016966A1,CC(=O)Nc1cc(B2OC(C)(C)C(C)(C)O2)ccn1.Cn1cc(Br)c2oc(CN3CCCC(F)(F)C3)cc2c1=O>>CC(=O)Nc1cc(-c2cn(C)c(=O)c3cc(CN4CCCC(F)(F)C4)oc23)ccn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,CCOC(C)=O,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20150065519A1,NC(=S)c1ccnc(Cc2ccccc2)c1.O=C(CBr)c1ccc(NS(=O)(=O)C(F)(F)F)cc1Cl>>O=S(=O)(Nc1ccc(-c2csc(-c3ccnc(Cc4ccccc4)c3)n2)c(Cl)c1)C(F)(F)F,,CCO,,,,test
US20090170907A1,Cc1cccc(C(=O)NN)c1.N#Cc1ccc(N(CC(=O)O)CC(F)(F)F)cc1C(F)(F)F>>Cc1cccc(C(=O)NNC(=O)CN(CC(F)(F)F)c2ccc(C#N)c(C(F)(F)F)c2)c1,,CC#N,,CCN=C=NCCCN(C)C,Cl,test
US20090054435A1,C=CCOC(=O)[C@H](C)O.COc1ccc(C(=O)c2ccc(OCc3ccccc3)cc2)c(O)c1>>CCCOC(=O)[C@@H](C)Oc1cc(OC)ccc1C(=O)c1ccc(O)cc1,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120101127A1,Nc1ccc(Cl)cc1.O=Cc1cccc([N+](=O)[O-])c1>>O=[N+]([O-])c1cccc(/C=N/c2ccc(Cl)cc2)c1,,Cc1ccccc1,,,,test
US05559101,O=C(OC[C@@H]1O[C@@H](n2ccc(=S)[nH]c2=O)[C@@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1)c1ccccc1>>O=c1[nH]c(=S)ccn1[C@@H]1O[C@@H](CO)[C@H](O)[C@@H]1O,,CO,N,,,test
US20150252038A1,NS(=O)(=O)C1CC1.O=C(O)c1cc(C2CC2)c(O[C@@H]2CCCN(Cc3cc(Cl)cc(Cl)c3)C2)cc1F>>O=C(NS(=O)(=O)C1CC1)c1cc(C2CC2)c(O[C@@H]2CCCN(Cc3cc(Cl)cc(Cl)c3)C2)cc1F,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20060128702A1,CSc1ccc(B(O)O)cc1.Clc1cc(Cl)c2ccccc2n1>>CSc1ccc(-c2cc(Cl)c3ccccc3n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20160046618A1,CC(C)(C)[S@](N)=O.O=C(CF)c1cccc(F)c1F>>CC(C)(C)[S@@](=O)/N=C(/CF)c1cccc(F)c1F,CC(C)O[Ti](OC(C)C)(OC(C)C)OC(C)C,C1CCOC1,,,,test
US04760087,CC(C)(C)[Si](C)(C)Cl.COc1cc(C=O)cc(OC)c1O>>COc1cc(C=O)cc(OC)c1O[Si](C)(C)C(C)(C)C,,CN(C)C=O,,c1c[nH]cn1,,test
US20090118275A1,CCOC(=O)c1nc(-c2ccccc2)sc1NC(N)=O>>Oc1nc(O)c2nc(-c3ccccc3)sc2n1,,CO,,Cl,[Na+].[OH-],test
US20130303492A1,NC(=O)c1c(Nc2cccc(Cl)c2)n[nH]c1N.O=Cc1ccc([N+](=O)[O-])cc1>>NC(=O)c1c(Nc2cccc(Cl)c2)n[nH]c1N=Cc1ccc([N+](=O)[O-])cc1,C1CCNCC1,CCO,,,,test
US20060128793A1,C1CN(CCN2CCOCC2)CCN1.COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CC[C@H](O)[C@@]2(C)C[C@H]1OC(C)=O>>COCC1OC(=O)C(=CN2CCN(CCN3CCOCC3)CC2)C2=C(O)C(=O)C3=C(C(OC(C)=O)CC4(C)C(O)CCC34)C21C,,ClCCl,,,,test
US20150284331A1,COc1cc2c(cc1OC)C(=O)C(CC1(F)CCN(C(=O)OC(C)(C)C)CC1)C2>>COc1cc2c(cc1OC)C(=O)C(CC1(F)CCNCC1)C2,,C1COCCO1,,Cl,,test
US20100261683A1,CC(C)c1cn[nH]c1N.CCOC(=O)CC(=O)OCC>>CC(C)c1cnn2c(O)cc(O)nc12,,CCO,,[Na],,test
US20090030082A1,CC(C)(C)c1cc(CBr)cc(C(C)(C)C)c1.COC(=O)Cc1cccc(OCCCNCC(c2ccccc2)c2ccccc2)c1>>COC(=O)Cc1cccc(OCCCN(Cc2cc(C(C)(C)C)cc(C(C)(C)C)c2)CC(c2ccccc2)c2ccccc2)c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20120004203A1,CCOC(=O)C(=Cc1ccc(C#N)cc1)C(C)=O.Nc1n[nH]c(N)n1>>CCOC(=O)C1=C(C)Nc2nc(N)nn2C1c1ccc(C#N)cc1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20150119362A1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.CN(C)C=O.O=C(O)Cc1ccc(Nc2nc(-c3cccc(Cl)c3)nc3c2SCCC3)cc1>>N#CNC(=O)Cc1ccc(Nc2nc(-c3cccc(Cl)c3)nc3c2SCCC3)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04997840,CCS(=O)(=O)Cl.Cn1cc(O)c(=O)c2ccc(F)cc21>>CCS(=O)(=O)Oc1cn(C)c2cc(F)ccc2c1=O,,ClCCl,,CCN(CC)CC,,test
US20020072533A1,Cc1ccc(S(=O)(=O)OC[C@H](CC(=O)OC(C)(C)C)[C@@H](C)C(C)C)cc1.[N-]=[N+]=[N-]>>CC(C)[C@H](C)[C@H](CN=[N+]=[N-])CC(=O)OC(C)(C)C,,CS(C)=O,,O,,test
US20070225267A1,C[N+](=O)[O-].O=Cc1cc(F)cc(OCc2ccccc2)c1>>O=[N+]([O-])/C=C/c1cc(F)cc(OCc2ccccc2)c1,,CC(=O)O,,C,O=C[O-].[NH4+],test
US20120108582A1,CCOC(=O)c1cn([C@@H]2C[C@@H]2F)c2c(C)c(N3C[C@H]4C(F)(F)CC[C@@]4(NC(=O)OC(C)(C)C)C3)c(F)cc2c1=O>>Cc1c(N2C[C@H]3C(F)(F)CC[C@@]3(NC(=O)OC(C)(C)C)C2)c(F)cc2c(=O)c(C(=O)O)cn([C@@H]3C[C@@H]3F)c12,,CCO,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[Na+].[OH-],test
US04898936,COC1C[C@H](O)[C@@H](CO)O1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC1C[C@H](O)[C@@H](COC(c2ccccc2)(c2ccccc2)c2ccccc2)O1,,c1ccncc1,,CO,,test
US20140163008A1,COCC(=O)Nc1c(C(=O)OC)cccc1[N+](=O)[O-]>>COCc1nc2c(C(=O)OC)cccc2[nH]1,,CC(=O)O,CCO,,,test
US20100076026A1,Clc1ccc(-n2nc3ccccc3c2NC2CCCCC2)cc1.O=C=NC1CCCCC1>>O=C(NC1CCCCC1)N(c1c2ccccc2nn1-c1ccc(Cl)cc1)C1CCCCC1,,Cc1ccccc1,,,,test
US20050137226A1,Cl.c1ccc2c(N(c3ccc(OC4CN5CCC4CC5)cc3)c3csc4ccccc34)csc2c1>>Cl.c1ccc2c(N(c3ccc(OC4CN5CCC4CC5)cc3)c3csc4ccccc34)csc2c1,,CCOC(C)=O,,C1COCCO1,,test
US20090118305A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(B2OC(C)(C)C(C)(C)O2)cc1-c1nc2ccccc2o1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ncc(Br)cc1-c1nc2ccccc2o1>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(Br)cc1-c1nc2ccccc2o1,CN(C)c1ccncc1,CN(C)C=O,,,,test
US20150057271A1,COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(c2)OCCN3)cc1.Cc1onc(-c2ccccc2)c1CBr>>Cc1onc(-c2ccccc2)c1CN1CCOc2cc(S(=O)(=O)Nc3nccs3)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20070207999A1,COC(=O)[C@@]1(C)CCCN1C(=O)c1c(N)cccc1[N+](=O)[O-]>>C[C@]1(C(=O)O)CCCN1C(=O)c1c(N)cccc1[N+](=O)[O-],,[K+],[OH-],,,test
US20140349990A1,Cc1cc([N+](=O)[O-])cnc1Cl.NN>>Cc1cc([N+](=O)[O-])cnc1NN,,CCO,,O,,test
US20130252980A1,CC(=O)Cl.Cc1c(Oc2cccc(/C=C3\SC(=O)NC3=O)c2)ncnc1OC1CCNCC1>>CC(=O)N1CCC(Oc2ncnc(Oc3cccc(/C=C4\SC(=O)NC4=O)c3)c2C)CC1,,ClCCl,,CCN(CC)CC,,test
US20080255155A1,C1CCNC1.O=C(NCCCl)Nc1ccc(Oc2cccc(NC(=O)N3CCN(c4ccc(F)cc4)C3=O)c2)cn1>>O=C(NCCN1CCCC1)Nc1ccc(Oc2cccc(NC(=O)N3CCN(c4ccc(F)cc4)C3=O)c2)cn1,,CS(C)=O,,,,test
US20090186879A1,CO.Nc1ccc(Br)cc1Cl>>COc1ccc(N)c(Cl)c1,I[Cu]I,CO,,Cl,C[O-].[Na+],test
US20050176727A1,C=Cc1cnccn1.COCN(Cc1ccccc1)C[Si](C)(C)C>>c1ccc(CN2CCC(c3cnccn3)C2)cc1,,O=C(O)C(F)(F)F,,,,test
US20110124622A1,COC(=O)c1cc2c(cc1Nc1ccc([Si](C)(C)C)cc1F)C(=O)NC2.ClI>>COC(=O)c1cc2c(cc1Nc1ccc(I)cc1F)C(=O)NC2,,ClCCl,,,,test
US20100280071A1,Cc1ccc([N+](=O)[O-])c(NC2CCN(C(=O)OC(C)(C)C)CC2)c1>>Cc1ccc(N)c(NC2CCN(C(=O)OC(C)(C)C)CC2)c1,[Pd],CCO,,,,test
US20120010237A1,CCOC(=O)CC(C)=O.COc1cc(N)ccc1Cl>>COc1cc2[nH]c(C)cc(=O)c2cc1Cl,Cc1ccc(S(=O)(=O)O)cc1,c1ccccc1,,,,test
US20080096874A1,CCOC(=O)C(C)=C1CCN(c2ncc([N+](=O)[O-])cc2C)CC1>>CCOC(=O)C(C)C1CCN(c2ncc(N)cc2C)CC1,[Pd],CCO,,,,test
US20020160996A1,BrBr.COc1cc(C)c(NC(=O)OC(C)(C)C)c(C)c1C>>COc1c(C)c(C)c(NC(=O)OC(C)(C)C)c(C)c1Br,,CC(=O)O,,O,CC(=O)[O-].[Na+],test
US20120101127A1,C=C(C)C.Cc1cc(F)ccc1N.O=Cc1cccc(Br)c1>>Cc1cc(F)cc2c1NC(c1cccc(Br)c1)CC2(C)C,,CC#N,CCOC(C)=O,O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3],,test
US20130029962A1,COCCOc1ccc(NC(=O)Oc2ccccc2)cn1.NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1>>COCCOc1ccc(NC(=O)NCc2cc(C(F)(F)F)nn2-c2cccc(Cl)c2)cn1,,CC#N,,CCN(CC)CC,,test
US20110251372A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O>>CC(C)C[C@H](N)C(=O)OCc1ccccc1,,CCOC(C)=O,CN(C)C=O,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20160185786A1,COC(=O)c1cnc(-c2ccc(C)cc2)n1N>>Cc1ccc(-c2ncc(C(=O)O)n2N)cc1,,O,,CO,[Li+].[OH-],test
US20050250822A1,CC(=O)OCC(F)(F)F.Cc1cc(I)ccc1NC(=O)OC(C)(C)C>>Cc1cc(C(=O)C(F)(F)F)ccc1NC(=O)OC(C)(C)C,,CCOCC,,Cl,[Li]CCCC,test
US20060211720A1,CO.Cc1cccc(C(=O)O)c1I>>COC(=O)c1cccc(C)c1I,,CO,c1ccccc1,C[Si](C)(C)C=[N+]=[N-],,test
US20010025049A1,COc1cccc2ccc(C(F)(F)F)nc12>>Oc1cccc2ccc(C(F)(F)F)nc12,,Br,,O,[Na+].[OH-],test
US20160137649A1,Clc1ccc(C(c2ccc(Cl)cc2)N2CC3CNCC3C2)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OC(C(F)(F)F)C(F)(F)F>>O=C(OC(C(F)(F)F)C(F)(F)F)N1CC2CN(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)CC2C1,,CC#N,O,CCN(C(C)C)C(C)C,,test
US20060178359A1,CCOC(=O)CCCCN1CCCc2cc(Br)ccc21.CN(C)C=O>>CCOC(=O)CCCCN1CCCc2cc(Br)cc(C=O)c21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080032972A1,CC(C)(C)OC(=O)NCC#Cc1cnc2c(c1)N(Cc1cc(Cl)ccc1Cl)CCN2>>NCC#Cc1cnc2c(c1)N(Cc1cc(Cl)ccc1Cl)CCN2,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20070232607A1,C1COCCN1.C[C@@H](Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)C(=O)O>>C[C@@H](Oc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)C(=O)N1CCOCC1,,CC(=O)N(C)C,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070105904A1,ClCc1cccc(Cl)n1.Nc1ccc(-c2cc(Cc3ccc(O)cc3)no2)c(N)n1>>Nc1ccc(-c2cc(Cc3ccc(OCc4cccc(Cl)n4)cc3)no2)c(N)n1,,CN(C)C=O,,C1CCOC1,[Na+].[OH-],test
US04537902,CCOC(=O)C(=O)OCC.N#CCCc1ccccc1>>CCOC(=O)C(=O)C(C#N)Cc1ccccc1,,CCO,,[Na],,test
US04552880,CCc1c[nH]c(=O)[nH]1.N#Cc1ccc(C(=O)Cl)cc1>>CCc1[nH]c(=O)[nH]c1C(=O)c1ccc(C#N)cc1,,O=[N+]([O-])c1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20140275172A1,COC(=O)c1cc(F)cc2cc(C3(C)OCCO3)oc12>>CC1(c2cc3cc(F)cc(CO)c3o2)OCCO1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090137595A1,Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1.O=C(Cl)c1cccnc1>>O=C(Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1)c1cccnc1,,CN1CCCC1=O,,Cl,,test
US20060223826A1,CC(c1c[nH]c2ccccc12)C(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O.COc1ccc(CCl)cc1>>COc1ccc(COC(=O)[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)[C@@H](C)c2c[nH]c3ccccc23)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20070105881A1,COC(=O)C(C#N)=C(Nc1cccc(F)c1)SC.N=C(N)CC1CCCC1>>N#Cc1c(Nc2cccc(F)c2)nc(CC2CCCC2)[nH]c1=O,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20110319431A1,CI.O=C(O)c1cc(Br)cc(I)c1>>COC(=O)c1cc(Br)cc(I)c1,,CN(C)C=O,,C1CCOC1,O=C([O-])[O-].[Na+].[Na+],test
US05998433,Cl.O=C(c1ccc(CCc2ccccc2)cc1)N1CCc2cc(CN3CCCC3)oc2C1>>Cl.O=C(c1ccc(CCc2ccccc2)cc1)N1CCc2cc(CN3CCCC3)oc2C1,,CO,,,,test
US20130225646A1,CS(=O)(=O)Cl.NC(C[N+](=O)[O-])c1ccccc1Cl>>CS(=O)(=O)NC(C[N+](=O)[O-])c1ccccc1Cl,,c1ccncc1,,Cl,,test
US20150266867A1,CC(C)(C)OC(=O)N=C(NC(=O)OC(C)(C)C)n1cccn1.CC(C)(C)OC(=O)NCCCO>>CC(C)(C)OC(=O)N=C(N(CCCNC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n1cccn1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140051676A1,O=C(O)c1cccnc1F.OCC(F)(F)F>>O=C(O)c1cccnc1OCC(F)(F)F,,Cl,O,CC(C)(C)[O-].[K+],,test
US06492403B1,CC(=O)Cl.COc1ccc(C(=O)O)cc1O>>COc1ccc(C(=O)O)cc1OC(C)=O,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20150065468A1,COc1cc2ncc(Br)cc2cc1OCCO.CS(=O)(=O)Cl>>COc1cc2ncc(Br)cc2cc1OCCOS(C)(=O)=O,,ClCCl,,CCOC(C)=O,,test
US20070043064A1,C#CCN(C(C)=O)c1cccc(C(=O)C=CN(C)C)c1.Nc1[nH]ncc1[N+](=O)[O-]>>C#CCN(C(C)=O)c1cccc(-c2ccnc3c([N+](=O)[O-])cnn23)c1,,CC(=O)O,,CCOC(C)=O,,test
US20040186116A1,CC(C)(C)[Si](C)(C)Oc1ccc2cc(CNC(=O)OCc3ccccc3)[nH]c2c1>>O=C(NCc1cc2ccc(O)cc2[nH]1)OCc1ccccc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06066641,CC(C)c1nc2c([nH]1)c(=S)[nH]c(=O)n2Cc1ccc(Cl)cc1.CCN>>CCNc1nc(=O)n(Cc2ccc(Cl)cc2)c2nc(C(C)C)[nH]c12,,O,,,,test
US20140323501A1,CC(N)=O.CCCC(=O)OCC(=O)c1ccc(Oc2ccc(CCC(NC(C)=O)(C(=O)OCC)C(=O)OCC)cc2)cc1>>CCCc1nc(-c2ccc(Oc3ccc(CCC(NC(C)=O)(C(=O)OCC)C(=O)OCC)cc3)cc2)co1,,Cc1ccccc1C,,CCOCC,FB(F)F,test
US20070010670A1,O=C(Cl)c1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1.c1ccc2c(c1)NCCO2>>O=C(c1cc([N+](=O)[O-])c(O)c([N+](=O)[O-])c1)N1CCOc2ccccc21,,CCOC(C)=O,,,,test
US20160151324A1,CSC[C@H](N)C(=O)O.OO>>CS(=O)CC(N)C(=O)O,,O,,,,test
US04618438,C/C=C/C.C=CCC.O=C1C=CC(=O)O1>>C=C(C)CC1CC(=O)OC1=O,,CCCCCCC,,,,test
US03947470,CCc1cc(C(=O)OC)cc(CC)c1O.COS(=O)(=O)OC>>CCc1cc(C(=O)OC)cc(CC)c1OC,,CCOCC,,O,[Na+].[OH-],test
US20160102083A1,COC(=O)c1csc(C(C)=O)c1C>>COC(=O)c1csc(C(C)O)c1C,,C1CCOC1,,[BH4-].[Na+],,test
US20020002163A1,Cc1cccc2c1N(CC(=O)C(C)(C)C)C(=O)C(NC(=O)OC(C)(C)C)N=C2c1ccccc1F>>Cc1cccc2c1N(CC(=O)C(C)(C)C)C(=O)C(N)N=C2c1ccccc1F,,CCOC(C)=O,,Cl,O=C([O-])O.[Na+],test
US04770692,CCOC(=O)C(C)Oc1ccnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl.O=[N+]([O-])O>>CCOC(=O)C(C)Oc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl,,CC(=O)OC(C)=O,,O=C([O-])O.[Na+],,test
US20110257148A1,CCC(C)I.OC1(c2cccc(F)c2F)CNC1>>CCC(C)N1CC(O)(c2cccc(F)c2F)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040077728A1,CCOC(=O)c1ccccc1C#C[C@H](C)CCCCO>>CCOC(=O)c1ccccc1CC[C@H](C)CCCCO,[Pd],CCO,,[H][H],,test
US05993780,C=Cc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1.O>>O=[N+]([O-])c1cc(CCO)cc([N+](=O)[O-])c1,,CC#N,,,,test
US20110039829A1,CCOC(=O)N1CCN(C(=O)[C@H](CN)NC(=O)c2cc(OCC(=O)C(C)(C)C)n(-c3ccccc3)n2)CC1.COC(=O)Cl>>CCOC(=O)N1CCN(C(=O)[C@H](CNC(=O)OC)NC(=O)c2cc(OCC(=O)C(C)(C)C)n(-c3ccccc3)n2)CC1,,CCN(CC)CC,ClCCl,O=C(O)C(F)(F)F,,test
US20070270422A1,CC(C)(C)OC(=O)N1CCNCC1.O=[N+]([O-])c1ccc(Oc2ccc(CCl)cc2)nc1>>CC(C)(C)OC(=O)N1CCN(Cc2ccc(Oc3ccc([N+](=O)[O-])cn3)cc2)CC1,,CN(C)C=O,,CCN(CC)CC,O,test
US20150299188A1,CC(C)(C)OC(=O)Nc1cc(Cl)nc(Cl)c1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)c1c(N)cc(Cl)nc1Cl,,CCOC(C)=O,,Cl,[Na+].[OH-],test
US04283420,CCOC(=O)C1(C(C)O)CCCCC1>>C=CC1(C(=O)OCC)CCCCC1,,c1ccccc1,,O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3,,test
US20080194629A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COCCCCC1(CNC(=O)[C@@H]2CNC[C@H](NS(=O)(=O)c3ccc(C=O)cc3)C2)c2ccccc2Oc2ccccc21>>COCCCCC1(CNC(=O)[C@H]2C[C@@H](NS(=O)(=O)c3ccc(C=O)cc3)CN(C(=O)OC(C)(C)C)C2)c2ccccc2Oc2ccccc21,,C1CCOC1,,CCN(CC)CC,O,test
US20090181947A1,CI.O=C1C=C2C(CCCN2Cc2ccc(Cl)nc2)O1>>CC12CCCN(Cc3ccc(Cl)nc3)C1=CC(=O)O2,,C1CCOC1,CCCCC,[Li]C(C)(C)C,,test
US20030013715A1,Cc1cnc2cc(F)ccc2n1.O=[Se]=O>>O=Cc1cnc2cc(F)ccc2n1,,CCOC(C)=O,,,,test
US04746671,CCOC(=O)CCCCO/N=C(/c1cccnc1)c1cccc(C(F)(F)F)c1>>O=C(O)CCCCO/N=C(/c1cccnc1)c1cccc(C(F)(F)F)c1,,CCO,,Cl,[Na+].[OH-],test
US04254116,CC(=O)OC(C)=O.CCCCCCCCCCCCCCCCCCC(C)c1cc(O)c2c(c1)OC(C)(C)c1ccncc1-2>>CCCCCCCCCCCCCCCCCCC(C)c1cc(OC(C)=O)c2c(c1)OC(C)(C)c1ccncc1-2,,c1ccncc1,,,,test
US05021413,CN1CCNC(CN2CCCC2)C1.Cl.Cl.O=C(Cl)C1CCc2cc(Cl)c(Cl)cc21>>CN1CCN(C(=O)C2CCc3cc(Cl)c(Cl)cc32)C(CN2CCCC2)C1.Cl.Cl,,CCN(CC)CC,,Cl,,test
US20150232460A1,CC(C)(C)OC(=O)NC1CC(F)(F)CC1NC(=O)c1ccccc1-n1nccn1.Cl>>Cl.NC1CC(F)(F)CC1NC(=O)c1ccccc1-n1nccn1,,C1COCCO1,,,,test
US20040082607A1,CC1=NN(c2ccc3c(=O)n(CC(C)C)c(CNC(=O)OC(C)(C)C)c(-c4ccccc4)c3c2)CO1>>CC1=NN(c2ccc3c(=O)n(CC(C)C)c(CN)c(-c4ccccc4)c3c2)CO1,,CCOC(C)=O,,Cl,,test
US05990116,COc1ccc(OC)c(C=O)c1.Nc1ccc2nc[nH]c(=O)c2c1>>COc1ccc(OC)c(CNc2ccc3nc[nH]c(=O)c3c2)c1,,CO,,,,test
US20150274753A1,C=C(CCl)COc1ccc(CNc2nc(Nc3ccc(C(=O)NCC(C)(C)CNC(=O)OC(C)(C)C)cc3)nc(OCC(F)(F)F)n2)cc1>>C=C(CCl)COc1ccc(CNc2nc(Nc3ccc(C(=O)NCC(C)(C)CN)cc3)nc(OCC(F)(F)F)n2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090169558A1,CCOC(=O)CBr.Oc1ccc(/C=C/I)cc1>>CCOC(=O)COc1ccc(/C=C/I)cc1,,CC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20160009667A1,CC1(C)CCc2cc(OCc3cc4onc(N)c4cc3Cl)ccc2C1.CS(=O)(=O)Cl>>CC1(C)CCc2cc(OCc3cc4onc(NS(C)(=O)=O)c4cc3Cl)ccc2C1,,ClCCl,,CCN(CC)CC,,test
US20110009607A1,CC(=O)OC[C@H]1O[C@@H](n2cc(C)c(=O)n(COCC(C)c3ccccc3[N+](=O)[O-])c2=O)C[C@@H]1O>>Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n(COCC(C)c2ccccc2[N+](=O)[O-])c1=O,,CO,,N,O,test
US05719139,CCN(C(C)C)C(C)C.C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=CCC(=O)C[C@H]12.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CSC1=CC=C(C(=O)OCc2ccc([N+](=O)[O-])cc2)N2C(=O)[C@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)[C@H]2C1,,CC#N,,,,test
US20100240671A1,CN(C)C(=O)[C@@H](N)Cc1ccc(-c2ccccc2)cc1.CN1CCN(c2nc(N)nc3cc(C(=O)O)ccc23)CC1>>CN1CCN(c2nc(N)nc3cc(C(=O)N[C@@H](Cc4ccc(-c5ccccc5)cc4)C(=O)N(C)C)ccc23)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150031708A1,COC(=O)Cn1cc(-c2nc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)ccc2C)ccc1=O>>Cc1ccc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)nc1-c1ccc(=O)n(CC(=O)O)c1,,C1COCCO1,,[Li+].[OH-],,test
US06018046,O=C(O)/C=C\C(=O)O.O=c1c(Cc2cccnc2)cn2c3cc(Br)ccc3c3cc(OCCCO)cc1c32>>O=C(O)/C=C\C(=O)O.O=c1c(Cc2cccnc2)cn2c3cc(Br)ccc3c3cc(OCCCO)cc1c32,,CO,,,,test
US20080125590A1,O=C1Cc2cc(-c3ccccc3)ccc2N1.O=Cc1ccc2cccccc1-2>>O=C1Nc2ccc(-c3ccccc3)cc2/C1=C/c1ccc2cccccc1-2,,CCO,,C1CCNC1,,test
US20150148337A1,CC(=N)NC(=O)c1ccc2c(c1)C(=O)N[C@@H](CC(=O)OC(C)(C)C)c1onc(C)c1-2>>Cc1noc(-c2ccc3c(c2)C(=O)N[C@@H](CC(=O)OC(C)(C)C)c2onc(C)c2-3)n1,,CC#N,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05624937,O=[N+]([O-])c1ccc(Sc2ccc3ccccc3n2)cc1>>Nc1ccc(Sc2ccc3ccccc3n2)cc1,[Pd],CN(C)C=O,,,,test
US20130225561A1,CO/C=C1\CCOc2cc(C#N)ccc21>>N#Cc1ccc2c(c1)OCCC2C=O,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20110288299A1,COC(=O)c1ccc(N(C)c2cc3c4c(c2)CCCC4CCC3)cc1>>CN(c1ccc(C(=O)O)cc1)c1cc2c3c(c1)CCCC3CCC2,,CCO,,Cl,[Na+].[OH-],test
US20090036420A1,COc1cccc(N)c1.CS(=O)(=O)c1ccc(C(=O)O)cc1>>COc1cccc(NC(=O)c2ccc(S(C)(=O)=O)cc2)c1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20070105943A1,N#Cc1ccc([N+](=O)[O-])s1.Oc1ccccc1>>N#Cc1ccc(Oc2ccccc2)s1,,CCOC(C)=O,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US04038396,Cc1cc(C(=O)O)c(C)c([N+](=O)[O-])c1.Cc1ccc(C(=O)O)c(C)c1N>>Cc1cc(N)c(C)c(C(=O)O)c1,[Pd],CO,,,,test
US20070185140A1,Clc1nc(-n2cnc3ccccc32)c2nc[nH]c2n1.NC1CCCCC1>>c1ccc2c(c1)ncn2-c1nc(NC2CCCCC2)nc2[nH]cnc12,,CS(C)=O,,,,test
US20150018332A1,CC(C)(C)OC(=O)N1CC2C(N)C2C1.O=C(Cl)OCC1c2ccccc2-c2ccccc21>>CC(C)(C)OC(=O)N1CC2C(C1)C2NC(=O)OCC1c2ccccc2-c2ccccc21,,C1COCCO1,O,O=C([O-])O.[Na+],,test
US20070073061A1,N#Cc1cc(CO)c2ccccc2c1>>N#Cc1cc(C=O)c2ccccc2c1,,CCOCC,ClCCl,,,test
US20140288123A1,CC[Mg]Br.O=Cc1ccc(Br)cc1>>CCC(O)c1ccc(Br)cc1,,C1CCOC1,,,,test
US20120214803A1,COc1ccc(C(=O)c2ccc3cccnc3c2[N+](=O)[O-])c(OC)c1>>COc1ccc(C(=O)c2ccc3cccnc3c2N)c(OC)c1,[Pd],CO,,C1CCOC1,,test
US20030166639A1,Cc1cccc(-c2cccc(C(=O)CC(=O)Nc3cc(C(F)(F)F)c(N(C)C)cc3NC(=O)OC(C)(C)C)c2)n1>>Cc1cccc(-c2cccc(C3=Nc4cc(N(C)C)c(C(F)(F)F)cc4NC(=O)C3)c2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130225524A1,COc1ncc(-c2ccc3c(Cl)c(C(N)=O)cnc3c2)c(OC)n1.Nc1cc(C(=O)O)cc(-c2ccco2)c1>>COc1ncc(-c2ccc3c(Nc4cc(C(=O)O)cc(-c5ccco5)c4)c(C(N)=O)cnc3c2)c(OC)n1,,CC(=O)O,,,,test
US20010046953A1,CC(=O)OC(C)=O.CCCCCCCCC(=O)NOC>>CCCCCCCCC(=O)N(OC)C(C)=O,,ClCCl,,CCN(CC)CC,,test
US20150004314A1,C1=COCCC1.Cl[Si](Cl)(Cl)Cl>>C1=COCCC1.Cl[Si](Cl)(Cl)Cl,,Cc1ccccc1,,,,test
US20090221597A1,COc1ccc(-c2nc(N)ncc2C)cn1.O=C(Cl)C1(c2ccc3c(c2)OC(F)(F)O3)CC1>>COc1ccc(-c2nc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)ncc2C)cn1,,c1ccncc1,,,,test
US20140256725A1,CC(C)Br.OCc1cccc(O)c1>>CC(C)Oc1cccc(CO)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140155389A1,CC(C)(C)OC(=O)N1CCNCC1.O=[N+]([O-])c1ccc(F)cn1>>CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)[O-])nc2)CC1,,Cc1ccccc1,,CCN(CC)CC,,test
US20110294758A1,COC(=O)c1cc(OC(C)C)cc(C(=O)c2ccc(P(=O)(OC(C)C)OC(C)C)cc2)c1>>COC(=O)c1cc(Cc2ccc(P(=O)(OC(C)C)OC(C)C)cc2)cc(OC(C)C)c1,,CO,,[BH4-].[Na+],,test
US20030216463A1,CC(C)(C)C(=O)Cl.CC(C)(C)[Si](C)(C)Oc1ccc2c(c1)OC(c1ccc(OCCN3CCCCC3)cc1)C1=C2COc2cc(O[Si](C)(C)C(C)(C)C)ccc21>>CC(C)(C)C(=O)Oc1ccc2c(c1)OC(c1ccc(OCCN3CCCCC3)cc1)C1=C2COc2cc(O)ccc21,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04709053,N.O=C(O)c1c[nH]cc1-c1cccc(Cl)c1Cl>>N#Cc1c[nH]cc1-c1cccc(Cl)c1Cl,,CCO,,,,test
US20070066639A1,CCCC(OC)(OC)OC.Nc1cnc2cc(Br)ccc2c1NCCCO>>CCCc1nc2cnc3cc(Br)ccc3c2n1CCCO,,Cc1ccccc1,,Cl,c1ccncc1,test
US05051508,COc1ccccc1N.O=C1OCCCC1=CO>>COc1ccccc1NC=C1CCCOC1=O,,CCO,,Cl,[Na],test
US20100130492A1,CC(C)Cn1c(N2CCN[C@@H](C)C2)nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc21.CS(=O)(=O)Cl>>CC(C)Cn1c(N2CCN(S(C)(=O)=O)[C@@H](C)C2)nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc21,,C1CCOC1,,CCN(CC)CC,,test
US05166152,N#CC(C(=O)Nc1ccccc1)C(=O)c1nn(-c2ccccc2)c2c1CSc1ccc(N)cc1-2.O=C1CCC(=O)O1>>N#CC(C(=O)Nc1ccccc1)C(=O)c1nn(-c2ccccc2)c2c1CSc1ccc(NC(=O)CCC(=O)O)cc1-2,,C1CCOC1,,,,test
US20060276447A1,Cc1cc2c(N)cccc2cn1.NC1CN(C(c2ccccc2)c2ccccc2)C1.O=C(Cl)Oc1ccccc1>>Cc1cc2c(NC(=O)NC3CN(C(c4ccccc4)c4ccccc4)C3)cccc2cn1,,ClCCl,,CCN(CC)CC,c1ccncc1,test
US04533661,CCOC(=O)CN1CCC[C@H](NP(=O)(CCCCCCN2C(=O)c3ccccc3C2=O)OCC)C1=O>>CCOC(=O)CN1CCC[C@H](NP(=O)(CCCCCCN)OCC)C1=O,,C1COCCO1,Cc1ccccc1,NN,O,test
US05608056,C=CCOC(=O)N1C[C@H](OS(C)(=O)=O)C[C@H]1CCOS(C)(=O)=O.O=Cc1c[nH]cn1>>C=CCOC(=O)N1C[C@H](OS(C)(=O)=O)C[C@H]1CCn1cncc1C=O,,CN(C)C=O,,O,CC(C)(C)[O-].[K+],test
US20050096337A1,CCOC(=O)C(C)(C)Oc1ccc(C(C)=O)c(F)c1.O=C(OO)c1cccc(Cl)c1>>CCOC(=O)C(C)(C)Oc1ccc(OC(C)=O)c(F)c1,,ClCCl,,,,test
US20130237571A1,O=C(CBr)c1ccccc1.OCc1ccc(O)cc1>>O=C(COc1ccc(CO)cc1)c1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110118230A1,Cn1cc(-c2cnc3c(c2)c2c(OC4CN(C(c5ccccc5)c5ccccc5)C4)c(C#N)ncc2n3S(=O)(=O)c2ccccc2)cn1>>Cn1cc(-c2cnc3[nH]c4cnc(C#N)c(OC5CNC5)c4c3c2)cn1,,CO,ClCCl,CC(Cl)OC(=O)Cl,,test
US20030109718A1,CC(C)(C)C=O.CNC(=O)[C@@H](N)Cc1ccccc1>>CN1C(=O)[C@H](Cc2ccccc2)N[C@@H]1C(C)(C)C,,C1CCOC1,,,,test
US20100125091A1,CCOC(=O)c1c(CCl)nc2ccc(Cl)cc2c1-c1ccccc1.COc1cc(Cl)ccc1O>>CCOC(=O)c1c(COc2ccc(Cl)cc2OC)nc2ccc(Cl)cc2c1-c1ccccc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US08053212B1,Cc1ccc(C(=O)Cl)cc1.Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O>>Cc1ccc(C(=O)C(O)[C@H]2O[C@@H](n3cc(C)c(=O)[nH]c3=O)C[C@@H]2O)cc1,,c1ccncc1,,,,test
US05159065,CCOC(=O)Cc1c(Cc2[nH]c(Cc3[nH]c(C(=O)OCc4ccccc4)c(C)c3CC(=O)OCC)c(CC)c2CC)[nH]c(C(=O)OCc2ccccc2)c1C>>CCOC(=O)Cc1c(Cc2[nH]c(Cc3[nH]c(C(=O)O)c(C)c3CC(=O)OCC)c(CC)c2CC)[nH]c(C(=O)O)c1C,[Pd],C1CCOC1,,,,test
US05843983,CCCCCCCCOC(=O)N1C[C@H](OC(=O)N(C)C)C[C@H]1CCCl.Oc1c(F)cccc1CCc1ccccc1>>CCCCCCCCOC(=O)N1C[C@H](OC(=O)N(C)C)C[C@H]1CCOc1c(F)cccc1CCc1ccccc1,,CC(=O)N(C)C,,CC(C)(C)[O-].[K+],,test
US20100179139A1,CC(C)(C)OC(=O)NCCNS(=O)(=O)c1ccc(-c2ccnc3[nH]c(C(F)(F)F)cc23)nc1>>NCCNS(=O)(=O)c1ccc(-c2ccnc3[nH]c(C(F)(F)F)cc23)nc1.O=CO,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090176778A1,CCOC(=O)c1nc2c(C(F)(F)F)cc(-c3ccco3)cn2c1Cl>>O=C(O)c1nc2c(C(F)(F)F)cc(-c3ccco3)cn2c1Cl,,C1COCCO1,Cl,,,test
US20100261698A1,Fc1ccc2cc(-c3cccnc3)[nH]c2c1.O=C=NS(=O)(=O)Cl>>N#Cc1c(-c2cccnc2)[nH]c2cc(F)ccc12,,ClCCl,,CN(C)C=O,,test
US20110028455A1,Cc1c(N)ccc2[nH]ccc12.Cc1ncc(C#N)c(Cl)c1Br>>Cc1ncc(C#N)c(Nc2ccc3[nH]ccc3c2C)c1Br,,CCO,,,,test
US20110105470A1,O=C(O)[C@@H]1CCCC[C@@H]1C(=O)O.O=C1C(=O)c2ccccc2C2=C1SCC1(CCNCC1)O2>>O=C([O-])[C@@H]1CCCC[C@@H]1C(=O)O.O=C1C(=O)c2ccccc2C2=C1SCC1(CC[NH2+]CC1)O2,,CC#N,,,,test
US20040009979A1,CC(C)(C)[Si](C)(C)OC(=O)C(O[Si](C)(C)C(C)(C)C)(C(F)(F)F)C(F)(F)F.CSc1ccc(Sc2ccc(N)c(F)c2)cc1>>CSc1ccc(Sc2ccc(NC(=O)C(O[Si](C)(C)C(C)(C)C)(C(F)(F)F)C(F)(F)F)c(F)c2)cc1,CN(C)C=O,ClCCl,c1ccncc1,O=C(Cl)C(=O)Cl,,test
US04340740,Cc1ccc(S(=O)(=O)OC(C#N)c2cccc(Oc3ccccc3)c2)cc1.Cc1ccc(S)cc1>>Cc1ccc(SC(C#N)c2cccc(Oc3ccccc3)c2)cc1,,CO,,O,C[O-].[Na+],test
US20140194411A1,CCOC(=O)N1CCc2cc(Br)c3c(c2CC1)C(C)(O)CC3>>CCOC(=O)N1CCc2cc(Br)c3c(c2CC1)C(C)=CC3,,C1COCCO1,,,,test
US20110224188A1,NC1(c2cocn2)CC1.O=C(NC1(C(=O)O)CC1)OCc1ccccc1>>O=C(NC1(C(=O)NC2(c3cocn3)CC2)CC1)OCc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080090845A1,CC(CC(=O)Cl)CC(F)(F)F.O=C1N[C@H](c2ccccc2)CO1>>C[C@@H](CC(=O)N1C(=O)OC[C@H]1c1ccccc1)CC(F)(F)F,,C1CCOC1,CCCCCC,,,test
US20060241127A1,C1CNCCN1.Nc1nc(Cl)cc(Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)n1>>Nc1nc(Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)cc(N2CCNCC2)n1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20060135552A1,CC(=O)CC(=O)C1CC1.COc1ccc(C(=O)c2c(N)sc3c2CCCC3)cc1>>COc1ccc(-c2c(C(=O)C3CC3)c(C)nc3sc4c(c23)CCCC4)cc1,O=S(=O)(O)O,CC(=O)O,,,,test
US20080119518A1,CN(C)C=O.COc1ccc(Br)cc1CC1COC(C)(C)O1>>COc1ccc(C=O)cc1CC1COC(C)(C)O1,,C1CCOC1,,[Li]CCCC,,test
US05344843,O=C(O)C(=O)c1ccc(OCCOc2ccc3ccccc3c2)cc1.OCCOCCOCCO>>O=C(OCCOCCOCCO)C(=O)c1ccc(OCCOc2ccc3ccccc3c2)cc1,,ClCCl,,,,test
US04426380,CC(=O)O.COC1CCC(OC)O1.COc1ccc(C)c(N)c1>>COc1ccc(C)c(-n2cccc2)c1,,CC(=O)O,,,,test
US20100190745A1,CCOC(=O)c1cn(CCO)c2c(F)cc(I)cc2c1=O>>CCOC(=O)c1cn2c3c(cc(I)cc3c1=O)OCC2,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US07435744B2,COc1ccc(N)cc1.O=C(CNc1ccc2[nH]c(=O)oc2c1)N1CCC(Oc2ccc(Cl)cc2)CC1>>COc1ccc(NCC(=O)N2CCC(Oc3ccc(Cl)cc3)CC2)cc1,,CCOCC,,,,test
US20110086898A1,BrCC1CC1.Cc1nn2c(-c3ccc(Cl)cc3Cl)coc2c1NC(=O)OC(C)(C)C>>Cc1nn2c(-c3ccc(Cl)cc3Cl)coc2c1N(CC1CC1)C(=O)OC(C)(C)C,,O,,CN(C)C=O,[H-].[Na+],test
US20090048320A1,CC(C)[Si](C#Cc1ccc(F)c(N2CCOCC2)c1)(C(C)C)C(C)C>>C#Cc1ccc(F)c(N2CCOCC2)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090082374A1,CNc1ccccc1.CO.Cc1nc(Cl)c2c3c(oc2n1)CCCC3>>COc1ccc(N(C)c2nc(C)nc3oc4c(c23)CCCC4)cc1,Cl,CCCCCC,CCOC(C)=O,CCCCO,,test
US20090075979A1,CCOC(=O)C[C@@H]1CC[C@@H](C(=O)O)CC1.C[C@H]1[C@@H](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC(=O)N1Cc1cc(OC(F)(F)F)ccc1N>>CCOC(=O)C[C@@H]1CC[C@@H](C(=O)Nc2ccc(OC(F)(F)F)cc2CN2C(=O)O[C@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H]2C)CC1,,C1CCOC1,CN(C)C=O,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20110118314A1,COc1cc(F)c(F)cc1-c1ccc(OCC2CCCN(C(=O)N(C)CC#N)C2)cc1.[N-]=[N+]=[N-]>>COc1cc(F)c(F)cc1-c1ccc(OCC2CCCN(C(=O)N(C)Cc3nnn[nH]3)C2)cc1,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US20130005707A1,CC(C)(C)OC(=O)N1CCC(Nc2n[nH]c3cc(Nc4nc5cccc(-c6ccccc6)n5n4)ccc23)CC1>>c1ccc(-c2cccc3nc(Nc4ccc5c(NC6CCNCC6)n[nH]c5c4)nn23)cc1,,Cl,,,,test
US20150105393A1,O=C(O)c1cc(F)c(OCC(F)(F)F)nc1Cl>>O=C(O)c1cnc(OCC(F)(F)F)c(F)c1,[Pd],CCO,,CCN(CC)CC,,test
US20140200350A1,CC(=O)Cl.CCN1c2ccccc2C(C)(C)c2cc3c(cc21)C(CC)(CC)c1ccccc1-3>>CCN1c2ccc(C(C)=O)cc2C(C)(C)c2cc3c(cc21)C(CC)(CC)c1ccccc1-3,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120094972A1,CC1(C)CNc2cc(N3CCOCC3)cnc21.Cc1c(N2CCCC2=O)nc2cc(F)cc(F)c2c1Br>>Cc1c(N2CCCC2=O)nc2cc(F)cc(F)c2c1N1CC(C)(C)c2ncc(N3CCOCC3)cc21,,Cc1ccccc1,,,,test
US20040006143A1,Clc1cccc([C@@H]2CO2)c1.NCCc1ccc(Sc2ccc(O)cc2)cc1>>Oc1ccc(Sc2ccc(CCNC[C@H](O)c3cccc(Cl)c3)cc2)cc1,,CCO,,,,test
US20140336168A1,CC(C)(C)OC(=O)N1CC(Oc2ccc([N+](=O)[O-])cc2)C1>>CC(C)(C)OC(=O)N1CC(Oc2ccc(N)cc2)C1,[Pd],C1CCOC1,,,,test
US20040186092A1,BrBr.COC(=O)c1ccc(N)c(OC)c1>>COC(=O)c1cc(Br)c(N)c(OC)c1,,CC(=O)O,CO,,,test
US20150284405A1,CC(=O)OO.COc1cc2cnccc2cc1C#N>>COc1cc2cnccc2cc1C#[N+][O-],,ClCCl,,,,test
US05663164,Cc1ccc(S(=O)(=O)OCC2C(NC(c3ccccc3)(c3ccccc3)c3ccccc3)C(=O)N2CC(=O)O)cc1.[N-]=[N+]=C(c1ccccc1)c1ccccc1>>Cc1ccc(S(=O)(=O)OC[C@@H]2[C@H](NC(c3ccccc3)(c3ccccc3)c3ccccc3)C(=O)N2CC(=O)OC(c2ccccc2)c2ccccc2)cc1,,C1COCCO1,CCOCC,,,test
US07737169B2,CC(=O)OCC(COC(C)=O)Oc1cccc2[nH]ccc12>>CC(=O)OCC(COC(C)=O)Oc1cccc2c1CCN2,,CC(=O)O,,[BH3-]C#N.[Na+],,test
US20160052922A1,CN.Clc1cc(Br)cc(OCC2CO2)c1>>CNCC(O)COc1cc(Cl)cc(Br)c1,,CO,,,,test
US20020065283A1,CCOC=C(C(C)=O)C(=O)Nc1ccc(C(F)(F)F)cc1.NO>>Cc1nocc1C(=O)Nc1ccc(C(F)(F)F)cc1,,CCO,O,Cl,[Na+].[OH-],test
US20050272114A1,ClCCCCCCI.O=C(NCCOCCO)OCc1c2ccccc2cc2ccccc12>>O=C(NCCOCCOCCCCCCCl)OCc1c2ccccc2cc2ccccc12,,CCCCCCC,CCOC(C)=O,C1CCOC1,[H-].[Na+],test
US20050176955A1,COC(=O)c1nc(N2CCCN(C)S2(=O)=O)c2cccnc2c1O>>CN1CCCN(c2nc(C(=O)O)c(O)c3ncccc23)S1(=O)=O,,C1COCCO1,O,Cl,[Na+].[OH-],test
US20150361100A1,Nc1ncnc2c1c(I)nn2Cc1cc2cccnn2c1-c1ccccn1.OB(O)c1cc(O)cc(F)c1>>Nc1ncnc2c1c(-c1cc(O)cc(F)c1)nn2Cc1cc2cccnn2c1-c1ccccn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20100210594A1,CCOP(=O)(CCO)OCC.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOP(=O)(COS(=O)(=O)C(F)(F)F)OCC,,CCOCC,ClCCl,Cc1cccc(C)n1,,test
US20110263571A1,Cc1ccc(N2CCN(C(=O)OC(C)(C)C)CC2=O)c(C)c1.Cl>>Cc1ccc(N2CCNCC2=O)c(C)c1.Cl,,ClC(Cl)Cl,,CCOC(C)=O,,test
US20060030612A1,N.O=C(O)c1cccc(Oc2ccc(-c3c4cccc(C(F)(F)F)c4nn3Cc3ccccc3)cc2)c1>>NC(=O)c1cccc(Oc2ccc(-c3c4cccc(C(F)(F)F)c4nn3Cc3ccccc3)cc2)c1,,C1COCCO1,,,,test
US20160194304A1,Cc1c(C(=O)N(C)c2ccc(OCc3ccccc3)cc2)cc(-c2cc3c(cc2C(=O)N2Cc4ccccc4C[C@H]2C)CN(C(=O)Cc2ccccc2)C3)n1C>>Cc1c(C(=O)N(C)c2ccc(O)cc2)cc(-c2cc3c(cc2C(=O)N2Cc4ccccc4C[C@H]2C)CN(C(=O)Cc2ccccc2)C3)n1C,[Pd],CCO,,,,test
US20060079687A1,COC(OC)c1cc(Oc2cccc(NC(=O)OCc3ccccc3)c2)ccc1[N+](=O)[O-]>>O=Cc1cc(Oc2cccc(NC(=O)OCc3ccccc3)c2)ccc1[N+](=O)[O-],,C1CCOC1,O,Cl,,test
US20030060472A1,Nc1ccc(Cl)cc1.O=C(CCl)c1cc(O)c(O)c([N+](=O)[O-])c1>>O=C(CNc1ccc(Cl)cc1)c1cc(O)c(O)c([N+](=O)[O-])c1,,CN(C)C=O,,[I-].[K+],,test
US05623081,CS(=O)(=O)Cl.N#CC1COCC1O>>CS(=O)(=O)O[C@@H]1COC[C@H]1C#N,,CCN(CC)CC,,,,test
US20150119385A1,C=O.COC(OC)c1nc2c(cc1CN1CCNC(C)(C)C1=O)CCCN2>>COC(OC)c1nc2c(cc1CN1CCN(C)C(C)(C)C1=O)CCCN2,,CO,,CCN(CC)CC,,test
US20040127538A1,COC(OC)c1ccc(F)c(C(O)c2cccc(F)c2)c1>>COC(OC)c1ccc(F)c(C(=O)c2cccc(F)c2)c1,,CS(C)=O,ClCCl,CCN(CC)CC,O,test
US04012377,CSc1ccc(C=O)s1.N#CC=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CSc1ccc(C=CC#N)s1,,ClC(Cl)Cl,,,,test
US20160235734A1,CC(C)(C)OC(=O)N1CC(COc2cccc([C@](O)(C(=O)OCC3CCN(Cc4ccccc4)CC3)c3ccccc3)c2)C1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=C(OCC1CCN(Cc2ccccc2)CC1)[C@](O)(c1ccccc1)c1cccc(OCC2CNC2)c1,,ClCCl,,,,test
US20070037781A1,CCC1(CC)OC(=O)N(CCC(C)(C)NCC(O)c2cc(OCc3ccccc3)cc3[nH]c(=O)ccc23)c2ccccc21>>CCC1(CC)OC(=O)N(CCC(C)(C)NCC(O)c2cc(O)cc3[nH]c(=O)ccc23)c2ccccc21,[Pd],CO,,[H][H],,test
US20150329472A1,Fc1cccc(Cl)c1F.Nc1cccc(Cl)c1F>>Nc1cccc(F)c1F,[Cu],,,,,test
US20080234237A1,Brc1ccc2c(c1)CCCN2.O=C(Cl)CCl>>O=C(CCl)N1CCCc2cc(Br)ccc21,,CCOC(C)=O,Cc1ccccc1,O=C([O-])O.[Na+],,test
US20100121095A1,CCOC(C)=O.CN(C)C(F)(F)C(F)F.O>>CCOC(=O)CC(=O)C(F)F,,CCO,,C,C[O-].[Na+],test
US20030195210A1,CCCBr.CCOC(=O)C(C#N)NC(C)=O>>CCCC(C#N)(NC(C)=O)C(=O)OCC,,CCO,,[Na],,test
US20050272791A1,COc1ccc(CCl)cc1.c1ccc(-c2c[nH]cn2)cc1>>COc1ccc(Cn2cnc(-c3ccccc3)c2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04623650,O=[N+]([O-])c1ccc(F)c(Br)c1F>>Nc1ccc(F)c(Br)c1F,,CCOCC,,Cl,[Na+].[OH-],test
US20060052599A1,COC(=O)c1ccc(Cl)nc1.NC1CCN(Cc2ccccc2)C1>>COC(=O)c1ccc(NC2CCN(Cc3ccccc3)C2)nc1,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US04602027,COC(=O)CC(NC(=O)C=Cc1ccccc1)C(C)=O>>Cc1oc(C=Cc2ccccc2)nc1CC(=O)O,,Cc1ccccc1,,O=P(Cl)(Cl)Cl,,test
US04997840,CN(C=O)c1ccc(F)cc1C(=O)CCl.O=C(O)c1ccccc1>>Cn1cc(OC(=O)c2ccccc2)c(=O)c2cc(F)ccc21,,ClCCl,,CCN(CC)CC,,test
US20120101134A1,CCOC(=O)CCCc1cccc(-c2noc(-c3cnc(OC(C)C)c(Cl)c3)n2)c1C>>Cc1c(CCCC(=O)O)cccc1-c1noc(-c2cnc(OC(C)C)c(Cl)c2)n1,,CC(C)O,O,Cl,[Na+].[OH-],test
US20050282843A1,CC(=O)c1c(C)c(C#N)n(C)c1C.CN(C)C(OC(C)(C)C)N(C)C>>Cc1c(C(=O)C=CN(C)C)c(C)n(C)c1C#N,,CO,,CCOCC,,test
US05498621,CCOC(=O)C(N)C(C)=O.O=C(Cl)C1CCCCC1>>CCOC(=O)C(NC(=O)C1CCCCC1)C(C)=O,,ClC(Cl)Cl,,CCN(CC)CC,Cl,test
US20120277440A1,CN(C)C(=O)Cl.ON=C1SCCN1Cc1ccc(Cl)nc1>>CN(C)C(=O)ON=C1SCCN1Cc1ccc(Cl)nc1,,CN(C)C=O,,,,test
US20040092737A1,CCOC(=O)C(C)(C)CC1CCN(Cc2ccccc2)CC1>>CC(C)(CO)CC1CCN(Cc2ccccc2)CC1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20040082625A1,COc1ccc(B(O)O)cc1.Nc1ccc(CO)cc1Br>>COc1ccc(-c2cc(CO)ccc2N)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],,test
US20150141406A1,CCOC(=O)/C=C/c1cc(Br)cn1[C@@H]1CCC[C@@H]1C>>C[C@H]1CCC[C@H]1n1cc(Br)cc1/C=C/C(=O)O,,C1CCOC1,,CO,[Na+].[OH-],test
US20110263548A1,COc1ccc(CBr)cc1.O=c1cc(Cl)c(-c2ccccc2)n[nH]1>>COc1ccc(Cn2nc(-c3ccccc3)c(Cl)cc2=O)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060235033A1,COc1cc2nccc(Oc3ccc(N)c(C)c3)c2cc1OC.Cc1cnc(C(C)N)s1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)NC(C)c4ncc(C)s4)c(C)c3)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20160009667A1,CC1(C)CCc2cc(OCc3cc4onc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c4cc3Cl)ccc2C1>>CC1(C)CCc2cc(OCc3cc4onc(N)c4cc3Cl)ccc2C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130116219A1,CC(C)CC=O.Cl.NCCc1c[nH]c2ccc(Br)cc12>>CC(C)CC1NCCc2c1[nH]c1ccc(Br)cc21.Cl,,O=S(=O)(O)O,,,,test
US20130203802A1,Fc1cccc(CCl)n1.O=C1c2ccccc2C(=O)N1c1cc[nH]n1>>O=C1c2ccccc2C(=O)N1c1ccn(Cc2cccc(F)n2)n1,,CC#N,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20070037802A1,Cc1ccc(S(=O)(=O)OCCOc2ccc3[nH]nc(S(=O)(=O)c4ccccc4)c3c2)cc1.N>>NCCOc1ccc2[nH]nc(S(=O)(=O)c3ccccc3)c2c1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20100120801A1,CC(C)(C)OC(=O)N1CCC(c2nc(Br)c(Br)n2CCOC2CCCCO2)CC1>>CC(C)(C)OC(=O)N1CCC(c2nc(Br)cn2CCOC2CCCCO2)CC1,,C1CCOC1,,[Li]CCCC,,test
US20030114443A1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.Sc1nc2cccc3ncc1n32>>CC(C)(C)OC(=O)N1CCC(Sc2nc3cccc4ncc2n43)CC1,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20100093703A1,NO.O=Cc1c[nH]c2ccc([N+](=O)[O-])cc12>>N#Cc1c[nH]c2ccc([N+](=O)[O-])cc12,,O=CO,,Cl,[Na+].[OH-],test
US20060205772A1,CN(CC1CCCCC1)C(=O)c1ccc([N+](=O)[O-])cc1>>CN(CC1CCCCC1)C(=O)c1ccc(N)cc1,[Pd],CCO,,[H][H],,test
US20060235004A1,ClCCCCBr.Oc1ncc(F)c(O)n1>>O=c1[nH]c(=O)n(CCCCCl)cc1F,,CN(C)C=O,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US20050234101A1,CC(=O)OC(C)=O.CC1CCN(CCOc2ccc(C#Cc3ncc(-c4ccc(Cl)cc4)cc3N)cc2)CC1>>CC(=O)Nc1cc(-c2ccc(Cl)cc2)cnc1C#Cc1ccc(OCCN2CCC(C)CC2)cc1,,ClCCl,,CCN(CC)CC,,test
US04780477,CC(C)CCN.CC(C)N(CCN1C(=O)/C(=N/NC(N)=O)c2ccccc21)C(C)C>>CC(C)CCNC(=O)N/N=C1\C(=O)N(CCN(C(C)C)C(C)C)c2ccccc21,,CN(C)C=O,Cc1ccccc1,,,test
US05004739,Cc1ccc([N+](=O)[O-])c(CC(=O)O)c1.O=Cc1ccc(Br)cc1>>Cc1ccc([N+](=O)[O-])c(C(=Cc2ccc(Br)cc2)C(=O)O)c1,,CC(=O)OC(C)=O,,CCN(CC)CC,,test
US20140336177A1,CC(C)(C)OC(=O)N1CCN[C@H](CO)C1.COc1ccc(C(=O)CBr)c(C)c1C#N>>COc1ccc(C(=O)CN2CCN(C(=O)OC(C)(C)C)C[C@H]2CO)c(C)c1C#N,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20040023950A1,c1ccc(CN2CCCC(Oc3ccc(-n4ccnc4)nn3)C2)cc1>>c1cn(-c2ccc(OC3CCCNC3)nn2)cn1,[Pd],CO,,,,test
US20110053979A1,C[C@H]1CC[C@@H](C=O)N(C(=O)OC(C)(C)C)C1.Nc1ccc(Br)cn1>>C[C@H]1CC[C@@H](CNc2ccc(Br)cn2)N(C(=O)OC(C)(C)C)C1,,ClCCCl,ClCCl,CC(=O)O,O=C([O-])O.[Na+],test
US06599917B1,COc1ncc(N(C)C(=O)OC(C)(C)C)cc1Cc1ccccc1>>CNc1cnc(OC)c(Cc2ccccc2)c1,,CCOC(C)=O,,Cl,,test
US20090030041A1,CC(=O)Nc1cccc(NC2CCN(Cc3ccccc3)CC2)c1>>Nc1cccc(NC2CCN(Cc3ccccc3)CC2)c1,,CCO,,O,[K+].[OH-],test
US20150252072A1,CC(C)[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)N1c2ncccc2C[C@H]1CNc1ccccc1.Cl>>CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ncccc2C[C@H]1CNc1ccccc1)C(C)C.Cl,,C1COCCO1,,,,test
US20090118259A1,COC(=O)c1ccc2c(c1)ncn2CCN=[N+]=[N-]>>[N-]=[N+]=NCCn1cnc2cc(C(=O)O)ccc21,,C1CCOC1,O,[Li+].[OH-],,test
US20110257151A1,COC(=O)c1ccc2c(c1)C(O)C(C)(C)C(c1ccccc1[N+](=O)[O-])N2>>COC(=O)c1ccc2c(c1)CC(C)(C)C(c1ccccc1N)N2,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US05281742,C=C(C)C(OC(=O)Nc1cc(OC(=O)Oc2cc(NC(=O)OC(C(=C)C)C(=O)OC)c(F)cc2Cl)c(Cl)cc1F)C(=O)OC>>CC(C)=C1OC(=O)N(c2cc(O)c(Cl)cc2F)C1=O,,CC(=O)O,,O=C([O-])[O-].[K+].[K+],,test
US20050143381A1,O=c1[nH]nc2c(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)cnn12.OCc1ccc(N2CCOCC2)nc1>>O=c1n(Cc2ccc(N3CCOCC3)nc2)nc2c(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)cnn12,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20120321559A1,COc1cccc(C2=NCCC2)c1>>COc1cccc(C2CCCN2)c1,,CCO,,[BH4-].[Na+],,test
US05719157,CCc1nc2cc(OC)c(OC)cc2c(-c2ccc(OC)c(OC)c2)c1C(=O)OC>>CCc1nc2cc(OC)c(OC)cc2c(-c2ccc(OC)c(OC)c2)c1C(=O)O,,O,,CO,[Na+].[OH-],test
US20050239980A1,BrC1=Cc2ccccc2C1.CC(C)PC(C)C>>CC(C)P(C1=Cc2ccccc2C1)C(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCN(CC)CC,,test
US20010011090A1,CCCCCC.Cc1ncsc1C(=O)O.Cl.ClCCCl.Nc1ccc(-n2nc(C(F)(F)F)cc2C(F)(F)F)cc1>>O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C(F)(F)F)cc1)c1ccc(Cl)cc1,,CCOC(C)=O,O,,,test
US05151225,N#CN=C(N)N.NC(N)=O.O.O=P(O)(O)O>>N=C(N)NC(N)=O.NC(N)=O.O=P(O)(O)O,,O,,,,test
US05605900,Cc1ccc2c(c1)c(=O)n(C1CCN(c3ncnc4cc(OCc5ccccc5)c(OCc5ccccc5)cc34)CC1)c(=O)n2C>>Cc1ccc2c(c1)c(=O)n(C1CCN(c3ncnc4cc(O)c(O)cc34)CC1)c(=O)n2C,,CCO,,CN(C)C=O,,test
US20100069395A1,CCOC(=O)c1cnc2ccnn2c1>>O=C(O)c1cnc2ccnn2c1,,[Na+],[OH-],CC(=O)O,O,test
US05298652,CCOC(=O)CN(CC(=O)OCC)C(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>CCOC(=O)CN(CC(=O)OCC)C(=O)c1cc(N)cc(N)c1,[Pd],C1CCOC1,,,,test
US20100311730A1,CO.N#Cc1ncc(N)nc1Cl>>COc1nc(N)cnc1C#N,,CO,O,C[O-].[Na+],,test
US20110152315A1,II.O=C(O)[C@@H]1C[C@H]1c1ccccc1>>O=C(O)[C@@H]1C[C@H]1c1ccc(I)cc1,,CC(=O)O,O,O=S(=O)(O)O,,test
US20080194562A1,COCc1cccc(Cl)c1C(=O)OC>>COCc1cccc(Cl)c1C(=O)O,,CO,,[Na+].[OH-],,test
US20070249670A1,COC(=O)[C@@H](NC(=O)c1ccc(F)cc1N)C1CCCCC1.Cc1cc(C)c(N=C=O)c(C)c1>>COC(=O)[C@@H](NC(=O)c1ccc(F)cc1NC(=O)Nc1c(C)cc(C)cc1C)C1CCCCC1,,c1ccncc1,,CCCCCC,CCOC(C)=O,test
US06255298B1,Nc1ccc(Cl)c(Cl)c1.O=C(O)c1cc(Br)ccc1O>>O=C(Nc1ccc(Cl)c(Cl)c1)c1cc(Br)ccc1O,,Clc1ccccc1,,ClP(Cl)Cl,,test
US20090054399A1,CNC.O=C(O)CN1CCCCn2c(c3c(c(O)c2=O)C(=O)N(Cc2ccc(F)c(Cl)c2)CC3)C1=O>>CN(C)C(=O)CN1CCCCn2c(c3c(c(O)c2=O)C(=O)N(Cc2ccc(F)c(Cl)c2)CC3)C1=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US05240925,ClCCN1CCOCC1.N#CCc1ccc(Cl)cc1>>N#CC(CCN1CCOCC1)c1ccc(Cl)cc1,,CN(C)C=O,Cc1ccccc1,[Na+].[OH-],,test
US20130267563A1,O=C(Cl)Cc1ccc(Cl)cc1.[C-]#[N+]CC(=O)OCC>>CCOC(=O)c1ncoc1Cc1ccc(Cl)cc1,,C1CCOC1,,CC(=O)O,[Li]CCCC,test
US20120238706A1,CC1(C)OC2(C)C(OCCOC3CCCCO3)CC1CC2OCCOC1CCCCO1>>CC1(C)OC2(C)C(OCCO)CC1CC2OCCO,,CO,,Cl,,test
US20060160786A1,CS(=O)(=O)OC1CN(C(c2ccccc2)c2ccccc2)C1.Oc1ccc(F)cc1Cl>>Fc1ccc(OC2CN(C(c3ccccc3)c3ccccc3)C2)c(Cl)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110118245A1,CC(C)(C)c1cc(NC(=O)Nc2cccc(O)c2)no1.COc1cc2c(Cl)ncnc2cc1OCCCl>>COc1cc2c(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)ncnc2cc1OCCCl,,C1CCOC1,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060211720A1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.Clc1ccc2[nH]cnc2c1>>Clc1ccc2c(c1)ncn2C(c1ccccc1)(c1ccccc1)c1ccccc1,,CCOC(C)=O,CN(C)C=O,,,test
US20110009454A1,Cc1ccccc1CBr.Nc1ncccc1C(=O)NCc1cccc(O)c1>>Cc1ccccc1COc1cccc(CNC(=O)c2cccnc2N)c1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20060019985A1,C=CC(=O)N1CCN(C(=O)OC(C)(C)C)CC1.COCN(Cc1ccccc1)C[Si](C)(C)C>>CC(C)(C)OC(=O)N1CCN(C(=O)C2CCN(Cc3ccccc3)C2)CC1,O=C(O)C(F)(F)F,Cc1ccccc1,,,,test
US06130239,C#CC1(O)CCOCC1.CC(=O)c1c[nH]c(/C=C2\C(=O)Nc3ccc(F)c(I)c32)c1>>CC(=O)c1c[nH]c(/C=C2\C(=O)Nc3ccc(F)c(C#CC4(O)CCOCC4)c32)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCN(CC)CC,CN(C)C=O,,,test
US20030125339A1,CC(C)c1ccc(N)cc1.O=C(O)c1cccnc1Cl>>CC(C)c1ccc(NC(=O)c2cccnc2Cl)cc1,,ClCCCl,ClCCl,CCN(C(C)C)C(C)C,On1nnc2ccccc21,test
US04608384,CCOC(=O)c1[nH]c2sc(C(=O)OCC)c(C)c2c1C(=O)c1ccc(Cl)cc1>>Cc1c(C(=O)O)sc2[nH]c(C(=O)O)c(C(=O)c3ccc(Cl)cc3)c12,,CCO,,[Na+].[OH-],,test
US20130336920A1,Cc1ccc(N)cc1C.O=[N+]([O-])c1ccc(N2CCCCC2)cc1-c1cc(F)ccn1>>Cc1ccc(Nc2ccnc(-c3cc(N4CCCCC4)ccc3[N+](=O)[O-])c2)cc1C,,CN(C)C=O,,[H-].[Na+],,test
US20160229856A1,CNCCCNC(=O)c1nn(C)cc1NC(=O)c1cccc(-c2cnn(CCCl)c2)n1>>CN1CCCNC(=O)c2nn(C)cc2NC(=O)c2cccc(n2)-c2cnn(c2)CC1,,CS(C)=O,,CCN(C(C)C)C(C)C,[I-].[K+],test
US20090281075A1,NCc1cccc(Cl)c1Cl.O=[N+]([O-])c1cnc(Br)cc1Br>>O=[N+]([O-])c1cnc(Br)cc1NCc1cccc(Cl)c1Cl,,C1CCOC1,,CCN(C(C)C)C(C)C,O,test
US20110288076A1,Cc1cc(F)ccc1C[C@@H]1C[C@@H](C(=O)Nc2ccc(Oc3ccc(F)cc3)cc2)N(C(=O)OC(C)(C)C)C1.O=C(O)C(F)(F)F>>Cc1cc(F)ccc1C[C@H]1CN[C@H](C(=O)Nc2ccc(Oc3ccc(F)cc3)cc2)C1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20150203486A1,COc1ccc(B(O)O)cn1.Nc1ccc(Br)cn1>>COc1ccc(-c2ccc(N)nc2)cn1,,C1COCCO1,CCOCC,O=C([O-])[O-].[K+].[K+],,test
US04263442,O=C(c1ccccc1)C(O)c1ccccc1.OCCS>>c1ccc(C2=C(c3ccccc3)SCCO2)cc1,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120165324A1,O=C(CCl)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1.O=C([O-])[O-].Sc1ccccc1>>Cc1ccc(SCC(=O)N2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)cc1,,CC#N,,O,,test
US20110003006A1,CC(=O)Nc1ccc(O)cc1.COc1ccc2c3c1O[C@H]1C(=O)CC[C@H]4[C@@H](C2)N(C)CC[C@]314.O=C(O)C(O)C(O)C(=O)O>>CC(=O)Nc1ccc(O)cc1.COc1ccc2c3c1O[C@H]1C(=O)CC[C@H]4[C@@H](C2)N(C)CC[C@]314.O=C(O)C(O)C(O)C(=O)O,,CC(C)=O,O,,,test
US20100144772A1,CCOC(=O)Cc1csc(NC(=O)C(C)(CC)Oc2ccc(F)cc2F)n1>>CCC(C)(Oc1ccc(F)cc1F)C(=O)Nc1nc(CC(=O)O)cs1,,CO,O,[Na+].[OH-],,test
US20070078136A1,Cc1c(Cl)nnc(N)c1Br.O=CCCl>>Cc1c(Cl)nn2ccnc2c1Br.Cl,,CCO,,,,test
US20080070903A1,CCC[Mg]Br.Cc1nc(S(C)(=O)=O)nc(-c2cc(Cl)cc(Cl)c2)c1C(=O)NCCCc1ccccc1>>CCCc1nc(C)c(C(=O)NCCCc2ccccc2)c(-c2cc(Cl)cc(Cl)c2)n1,,C1CCOC1,CCOC(C)=O,Cl,,test
US20110118248A1,CCc1cc(S(=O)(=O)Nc2cc(Cl)cnc2Br)ccc1Cl.COCCl>>CCc1cc(S(=O)(=O)N(COC)c2cc(Cl)cnc2Br)ccc1Cl,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US03978071,CCOC(=O)C(C)c1ccc(-c2cn3cccnc3n2)cc1>>CC(C(=O)O)c1ccc(-c2cn3cccnc3n2)cc1,,O,,CCO,[Na+].[OH-],test
US04962113,O=C=Nc1cccc2ccccc12.OCCO>>O=C(Nc1cccc2ccccc12)OCCO,,O,,,,test
US20120004447A1,CC[NH+](CC)CC.O=S([O-])C(F)(F)CO.OO>>CC[NH+](CC)CC.O=S(=O)([O-])C(F)(F)CO,,O,,,,test
US04450157,CSC1=NC(C)(C)SC1.O=N[O-]>>CSC1=NC(C)(C)SC1=NO,,O,,CC(=O)O,,test
US20080167314A1,Cc1cc(-c2nc3cccnn3c2-c2ccnc(N)c2)ccc1F.O=C(Cl)c1ccc(F)cc1>>Cc1cc(-c2nc3cccnn3c2-c2ccnc(NC(=O)c3ccc(F)cc3)c2)ccc1F,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20070179151A1,COc1cc(CCC(=O)O)cc(OC)c1>>COc1cc2c(c(OC)c1)C(=O)CC2,,CS(=O)(=O)O,,[Na+].[OH-],,test
US20150111877A1,CCOC(COc1ncc([N+](=O)[O-])cc1[N+](=O)[O-])OCC>>O=CCOc1ncc([N+](=O)[O-])cc1[N+](=O)[O-],,O=CO,,,,test
US20060217380A1,CN(C)CCCN(C)c1ccc(Cl)cc1[N+](=O)[O-]>>CN(C)CCCN(C)c1ccc(Cl)cc1N,[Ni],CCO,O,,,test
US05578620,[N-]=[N+]=NCC(O)Cc1ccccc1>>NCC(O)Cc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150252030A1,OB(O)c1ccsc1.Oc1cccnc1Br>>Oc1cccnc1-c1ccsc1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20060281794A1,Nc1c(C(=O)O)[nH]c(=O)[nH]c1=O.O=C=Nc1cccc(C(F)(F)F)c1>>O=C(Nc1cccc(C(F)(F)F)c1)Nc1c(C(=O)O)[nH]c(=O)[nH]c1=O,,CS(C)=O,,O,,test
US20060063762A1,C[C@H](Oc1cccc2c(CC(C)(C)NC(=O)OC(C)(C)C)c[nH]c12)C(=O)N1CCOCC1>>C[C@H](Oc1cccc2c(CC(C)(C)N)c[nH]c12)C(=O)N1CCOCC1,,C1COCCO1,ClCCl,Cl,O=C([O-])O.[Na+],test
US09365574B2,COC(=O)C(C)(Br)c1cnccn1.N#CCC#N>>COC(=O)C(C)(c1cnccn1)C(C#N)C#N,,CN(C)C=O,,[H-].[Na+],,test
US06498172B1,CC(C)(C)OC(=O)COc1cccc(CN)c1.O=Cc1ccc(-c2cnccn2)cc1>>CC(C)(C)OC(=O)COc1cccc(CNCc2ccc(-c3cnccn3)cc2)c1,,CCN(CC)CC,,,,test
US20060025445A1,CCNC(C)C(=O)c1ccccc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>CCN(C(C)C(=O)c1ccccc1)S(=O)(=O)c1ccc(Cl)cc1,,ClCCl,,CCN(CC)CC,,test
US20050020830A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1nccc2c1CC1CNCC2C1>>COc1nccc2c1CC1CC2CN(C(=O)OC(C)(C)C)C1,,ClCCl,O,,,test
US08138168B1,CC(C)(C)OC(=O)N[C@@H](CC(=O)O)Cc1ccc2ccccc2c1.COCCCn1c(C2CCCNC2)nc2ccc(OC)nc21>>COCCCn1c(C2CCCN(C(=O)C[C@@H](Cc3ccc4ccccc4c3)NC(=O)OC(C)(C)C)C2)nc2ccc(OC)nc21,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US07396844B1,COC(=O)c1ccc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cc1>>CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(C(=O)O)cc2)CC1,,C1CCOC1,CO,[Na+].[OH-],,test
US05066680,CN(C)CC#CCNC(=O)C(O)(c1ccccc1)C1CCCCC1.Cl>>CN(C)CC#CCNC(=O)C(O)(c1ccccc1)C1CCCCC1.Cl,,CO,,,,test
US20090018160A1,C#CCCCc1ccccc1.CCCCC#Cc1c[nH]nc1C1=CCCN(C)C1.CCOCC.O=S(=O)(c1ccccc1)n1cc(I)c(-c2cccnc2)n1>>CCCCCCCC#Cc1c[nH]nc1-c1cccnc1.O=S(=O)(c1ccccc1)n1cc(C#CCCCc2ccccc2)c(-c2cccnc2)n1,,CCOC(C)=O,CCOCC,,,test
US20090258877A1,Cl.Fc1ccc(-c2cn3ncnc3c(Cl)n2)c(F)c1.NCCNc1ccc(C(=O)C(F)(F)F)c(N)n1>>Cl.Nc1nc(NCCNc2nc(-c3ccc(F)cc3F)cn3ncnc23)ccc1C(=O)C(F)(F)F,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US20050245530A1,COC(=O)c1cccn(-c2ccccc2)c1=O>>O=C(O)c1cccn(-c2ccccc2)c1=O,,CS(C)=O,,[H-].[Na+],,test
US20150148349A1,CC1(C)CCCN(NC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)OC(C)(C)C)C1.O=C(O)C(F)(F)F>>CC1(C)CCCN(NC(=O)[C@@H]2C[C@H]3C[C@H]3N2)C1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20110190297A1,Clc1c(Br)cncc1Br.N#CC1CCNC1>>N#CC1CCN(c2c(Br)cncc2Br)C1,,CN1CCCC1=O,,CCN(CC)CC,,test
US05169848,CC(C)(C)n1ncc(Cl)c(Cl)c1=O.OCc1ccc(OC(F)(F)C(F)OC(F)(F)F)cc1>>CC(C)(C)n1ncc(OCc2ccc(OC(F)(F)C(F)OC(F)(F)F)cc2)c(Cl)c1=O,,CCOCC,CN(C)C=O,[H-].[Na+],,test
US04963566,CN1CCCc2cccc(CO)c21.O=S(Cl)Cl>>CN1CCCc2cccc(CCl)c21,,ClCCl,,,,test
US20070197512A1,CCOC(=O)CCCN1C(=O)C(C(C)C)Oc2c(C(C)C)cccc21.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)CCCN1C(=S)C(C(C)C)Oc2c(C(C)C)cccc21,,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US20130072467A1,COCCOCCN.O=C1NC(=S)CS1>>COCCOCCNC1=NC(=O)SC1,,CCO,,,,test
US06147148,CCCCCCCC(=O)O.NCCCC[C@H](N)C(=O)O>>CCCCCCCC(=O)NCCCC[C@H](N)C(=O)O,,Cc1ccccc1C,,O,,test
US20110034450A1,CC(C)(C)OC(=O)C(c1ccc(CBr)cc1)C1CCCC1.O=C1NCc2c(F)cccc21>>CC(C)(C)OC(=O)C(c1ccc(CN2Cc3c(F)cccc3C2=O)cc1)C1CCCC1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20150274691A1,CC(=O)CCOCc1ccccc1.C[Si](C)(C)Cl>>C=C(CCOCc1ccccc1)O[Si](C)(C)C,,C1CCOC1,CCCCC,CC(C)[N-]C(C)C.[Li+],,test
US20080081802A1,CN(C)C(=O)c1ccc(-n2nc(-c3cccnc3)c3c2-c2sc(N)nc2CC3)c(Cl)c1>>CN(C)Cc1ccc(-n2nc(-c3cccnc3)c3c2-c2sc(N)nc2CC3)c(Cl)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140228386A1,Clc1cc(I)ccn1.O=C1NCCN1c1cnccc1C1CC1>>O=C1N(c2ccnc(Cl)c2)CCN1c1cnccc1C1CC1,I[Cu]I,,,CN[C@@H]1CCCC[C@H]1NC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20130172343A1,NC1=NC2(c3cc(-c4cccnc4F)ccc3Oc3cnc(C4=CCOCC4)cc32)c2ccccc21.O=C(O)C(F)(F)F>>NC1=NC2(c3cc(-c4cccnc4F)ccc3Oc3cnc(C4CCOCC4)cc32)c2ccccc21.O=C(O)C(F)(F)F,,CO,,,,test
US20160221972A1,CI.COC(=O)c1ccc2c(c1)CN(Cc1ccc(OC)cc1)CC(=O)N2>>COC(=O)c1ccc2c(c1)CN(Cc1ccc(OC)cc1)CC(=O)N2C,,CN(C)C=O,O,[H-].[Na+],,test
US20100222318A1,CC(=O)OCc1ccc(-c2nnc(-c3nc(-c4ccc(C(=O)N(C)C)cc4)cnc3N)o2)cc1>>CN(C)C(=O)c1ccc(-c2cnc(N)c(-c3nnc(-c4ccc(CO)cc4)o3)n2)cc1,,CO,,Cl,[Na+].[OH-],test
US04150139,CC1(Cn2c(Cc3ccccc3)n[nH]c2=S)OCCO1>>CC(=O)Cn1c(Cc2ccccc2)n[nH]c1=S,,CCO,,Cl,,test
US04859684,COn1c(C)nc2cc(C(=O)c3ccccc3)ccc21>>COn1c(C)nc2cc(C(O)c3ccccc3)ccc21,,CO,,[BH4-].[Na+],,test
US20100152160A1,COC(=O)/C=C\CNc1cc(Cl)ccc1O>>COC(=O)CC1CNc2cc(Cl)ccc2O1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20080090856A1,CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc4c(c3)CCN(C(=O)OCc3ccccc3)C4)c(F)c2)ccn1>>CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc4c(c3)CCNC4)c(F)c2)ccn1,[Pd],CO,,O=CO,,test
US05696148,CCOC(=O)CC#N.O=CC1(Cl)Cc2ccccc2N1Cc1cccc(Cl)c1>>CCOC(=O)C(C#N)=Cc1c(Cl)n(Cc2cccc(Cl)c2)c2ccccc12,,CCO,,O,O=C([O-])[O-].[K+].[K+],test
US06689922B1,CC(C)(O)CCCCCc1cccc(C=Cc2cc(O)cc(O)c2)c1>>CC(C)(O)CCCCCc1cccc(CCc2cc(O)cc(O)c2)c1,[Pd],,,,,test
US20130079377A1,Cc1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(CNS(=O)(=O)NC(=O)OC(C)(C)C)cc2)c1>>Cc1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(CNS(N)(=O)=O)cc2)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US20130109718A1,COP(=O)(CC(=O)C1CCC(OC2CCCCO2)CC1)OC.O=Cc1ccc(Br)cc1>>O=C(/C=C/c1ccc(Br)cc1)[C@@H]1CC[C@@H](OC2CCCCO2)CC1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20140170207A1,CC(C)CC(N)C(=O)O.CCCCCCCCCCCCO>>CCCCCCCCCCCCOC(=O)C(N)CC(C)C,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20100137299A1,CN1CCN(CN2C(=O)C3(COc4cc5c(cc43)OCO5)c3ccccc32)CC1.Cl>>CN1CCN(CN2C(=O)C3(COc4cc5c(cc43)OCO5)c3ccccc32)CC1.Cl,,CO,,,,test
US20110288067A1,CC(C)(C#N)C(NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(C3CC3)nc12)C1CC1>>CC(C)(C#N)C(NC(=O)c1c[nH]c2ncc(C3CC3)nc12)C1CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070004709A1,Cc1csc2c1S(=O)(=O)N=CN2C>>Cc1csc2c1S(=O)(=O)NCN2C,,CC(C)O,O,Cl,[BH4-].[Na+],test
US05684004,CCN(CC)CCCCCCOc1ccc(/C(=C(/Cl)c2ccccc2)c2ccccc2)cc1.O=C(O)CC(O)(CC(=O)O)C(=O)O>>CCN(CC)CCCCCCOc1ccc(/C(=C(/Cl)c2ccccc2)c2ccccc2)cc1.O=C(O)CC(O)(CC(=O)O)C(=O)O,,CCO,,,,test
US20050256218A1,CC(=O)CC(C)=O.CCC(C)=O>>CC(=O)CCC(C(C)=O)C(C)=O,CCN(CC)CC,CCC(C)=O,,,,test
US20050288329A1,CC(C)(Sc1ccc(O)cc1)C(=O)NC1CCCCC1.CCI>>CCOc1ccc(SC(C)(C)C(=O)NC2CCCCC2)cc1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US04556711,Br.O=C(Nc1ccc(-c2c[nH]c(=O)cn2)cc1)OCc1ccccc1>>Br.Nc1ccc(-c2c[nH]c(=O)cn2)cc1,,CC(=O)O,,,,test
US20140031391A1,O=S(Cl)Cl.OCc1ccc(CCc2ccc(F)cc2)cc1>>Fc1ccc(CCc2ccc(CCl)cc2)cc1,,ClCCl,,O=C([O-])O.[Na+],,test
US20100216836A1,BrCC1COc2ccccc2O1.NC(=O)C1CCCNC1>>NC(=O)C1CCCN(CC2COc3ccccc3O2)C1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20090306139A1,COC(=O)C1CC(c2ccc(OC(F)(F)F)cc2)CN(C(=O)N2CCC(O)CC2)C1>>O=C(O)C1CC(c2ccc(OC(F)(F)F)cc2)CN(C(=O)N2CCC(O)CC2)C1,,CO,O,Cl,CC(C)(C)[O-].[K+],test
US20110230537A1,CON=C(C)Cc1ccc(Oc2ccc(Cl)cc2)cc1>>CONC(C)Cc1ccc(Oc2ccc(Cl)cc2)cc1,,CC(=O)O,,[BH3-]C#N.[Na+],,test
US20120264734A1,CCc1c(N)cc(Cl)cc1C(=O)OC.O=C1CCOCC1>>CCc1c(NC2CCOCC2)cc(Cl)cc1C(=O)OC,,ClCCCl,O,CC(=O)O,O=C([O-])O.[Na+],test
US20080200365A1,C=C1C(=O)CC(C)C12CC(C)(C)CC(C)(C)C2.O=C(OO)c1cccc(Cl)c1>>C[C@H]1CC(=O)[C@]2(CO2)C12CC(C)(C)CC(C)(C)C2,,ClCCl,,,,test
US20150376160A1,CC(O)c1ccc(Cl)cc1F.CCOC(=O)C1(c2ccc(-c3ccc(-c4sc(F)cc4C(=O)O)cc3)cc2)CC1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4sc(F)cc4NC(=O)OC(C)c4ccc(Cl)cc4F)cc3)cc2)CC1,,Cc1ccccc1,,CCN(CC)CC,[Cl-].[NH4+],test
US20060014739A1,N#Cc1ccc(N2C3CCC2CC(N)C3)c2ccccc12.O=C(Cl)CCCl>>N#Cc1ccc(N2C3CCC2CC(NC(=O)CCCl)C3)c2ccccc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US05059608,CC1(c2ccccc2)NCCc2ccccc21.CI>>CN1CCc2ccccc2C1(C)c1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US04788320,CCOC(=O)C(C(=O)OCC)C(=O)c1cc(F)c(F)c(Cl)c1Cl>>CCOC(=O)CC(=O)c1cc(F)c(F)c(Cl)c1Cl,,O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20130274287A1,Cc1ccc(Br)cc1C.O=C1CCCc2c(Br)cncc21>>Cc1ccc(C2(O)CCCc3c(Br)cncc32)cc1C,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US05015666,COc1ccc(Br)cc1.O=C(Cc1ccccc1)c1ccccc1>>COc1ccc(C(O)(Cc2ccccc2)c2ccccc2)cc1,,CCOCC,,O=S(=O)(O)O,,test
US20160108046A1,O=P(Cl)(Cl)Cl.O=S(=O)(c1ccccc1)n1ccc2c1cc(Br)c[n+]2[O-]>>O=S(=O)(c1ccccc1)n1ccc2nc(Cl)c(Br)cc21,,ClCCl,,CCN(CC)CC,,test
US06420367B1,Brc1ccco1.Cc1ccc(B(O)O)cc1>>Cc1ccc(-c2ccco2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20110301167A1,CCOC(=O)c1nn(Cc2ccc(I)cc2)c2c(Cl)cccc2c1=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)c1nn(Cc2ccc(I)cc2)c2c(Cl)cccc2c1=S,,Cc1ccccc1,,,,test
US20150239884A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1nccc2cnc(OCc3ccccc3)cc12>>O=S(=O)(Oc1nccc2cnc(OCc3ccccc3)cc12)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20040116707A1,CC(C)(C)OC(=O)NC1CC(=O)N(c2ccc(OCc3ccccc3)cc2)C1>>CC(C)(C)OC(=O)NC1CC(=O)N(c2ccc(O)cc2)C1,[Pd],C1CCOC1,,,,test
US20100093694A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cccc(C(=O)O)c3)cc12.CNCc1ccccc1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cccc(C(=O)N(C)Cc4ccccc4)c3)cc12,,CN(C)C=O,CO,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100105667A1,CCN1CCN(Cc2cnc3c(C(=O)O)ccc(-c4c(Cl)c(OC)cc(OC)c4Cl)c3n2)CC1.Nc1cccnc1>>CCN1CCN(Cc2cnc3c(C(=O)Nc4cccnc4)ccc(-c4c(Cl)c(OC)cc(OC)c4Cl)c3n2)CC1,,CO,ClCCl,,,test
US20030225228A1,CC(C)(C)OC(=O)Nn1c(-c2ccccc2)ccc1-c1ccccc1>>Nn1c(-c2ccccc2)ccc1-c1ccccc1,,CO,,Cl,,test
US05061725,O=C(CN1CCNCC1)N1CCOCC1.O=C(O)CN1CCCC1=O>>O=C(CN1CCN(C(=O)CN2CCCC2=O)CC1)N1CCOCC1,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US04180662,COC(=O)C1=C(O)c2cc(Cl)sc2S(=O)(=O)N1C.Nc1nccs1>>CN1C(C(=O)Nc2nccs2)=C(O)c2cc(Cl)sc2S1(=O)=O,,Cc1ccccc1C,,,,test
US04906759,CC(O)=S.COC(=O)/C=C(\CCl)OC>>COC(=O)/C=C(\COC(C)=S)OC,,CO,,[Na],,test
US20100099728A1,BrCc1cccc(OCc2ccccc2)c1.O=C1Nc2ccccc2C12COc1cc3c(cc12)CCO3>>O=C1N(Cc2cccc(OCc3ccccc3)c2)c2ccccc2C12COc1cc3c(cc12)CCO3,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US03981930,CC(C)=O.CC(CC=O)CCCC(C)(C)O>>CC(=O)C=CCC(C)CCCC(C)(C)O,,CC(C)=O,,,,test
US20030225081A1,COC(=O)Cl.O=C(O)CNc1ccccc1>>COC(=O)N(CC(=O)O)c1ccccc1,,COC(C)(C)C,,[Na+].[OH-],,test
US20050153959A1,COCn1cc2cc(CC(OC(=O)N3CCC(c4cc5ccccc5[nH]c4=O)CC3)c3ncc[nH]3)cc(C)c2n1.Fc1cc(F)cc(CBr)c1>>COCn1cc2cc(C[C@@H](OC(=O)N3CCC(c4cc5ccccc5[nH]c4=O)CC3)c3nccn3Cc3cc(F)cc(F)c3)cc(C)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080009530A1,COCCCOc1ccc(/C=C(\OC)C(=O)OC)c(O)c1.FC(F)(F)c1cnc(Cl)c(Cl)c1>>COCCCOc1ccc(/C=C(\OC)C(=O)OC)c(Oc2ncc(C(F)(F)F)cc2Cl)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070269664A1,CCCCOc1c(C)cc(C=COC)cc1C>>CCCCOc1c(C)cc(CC=O)cc1C,,CC#N,,Cl,O=C([O-])O.[Na+],test
US20080306050A1,CCOC(=O)N(CC#N)Cc1ccccc1[N+](=O)[O-]>>CCOC(=O)N1CC(N)=Nc2ccccc2C1,[Fe],CC(=O)O,,CO,ClCCl,test
US20060183904A1,BrBr.CC(=O)Nc1ccc(C)c(C)c1>>CC(=O)Nc1cc(C)c(C)cc1Br,,CC(=O)O,,O,,test
US04855086,CCOC(=O)/C(C)=C/CCC#Cc1ccccc1>>C/C(=C\CCC#Cc1ccccc1)C(=O)O,,O,,CCO,[K+].[OH-],test
US20100272680A1,O=C(O)c1nc2c(C(F)(F)F)cc(OC(F)F)cn2c1Cl.O=C1OCCN1C1CCNCC1>>O=C(c1nc2c(C(F)(F)F)cc(OC(F)F)cn2c1Cl)N1CCC(N2CCOC2=O)CC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04327101,CCI.CCOC(=O)c1c[nH]c2c(F)c(C)c(F)cc2c1=O>>CCOC(=O)c1cn(CC)c2c(F)c(C)c(F)cc2c1=O,,CN(C)C=O,O,[H][H],[H-].[Na+],test
US20070032515A1,CCOC(=O)Cc1ccccc1.COc1cccc(CC#N)c1>>COc1cccc(C(C#N)C(=O)Cc2ccccc2)c1,,CCO,,C,C[O-].[Na+],test
US20090143444A1,CCOC(=O)CC#N.O=C(CBr)c1ccccc1F>>CCOC(=O)C(C#N)CC(=O)c1ccccc1F,,CC(C)=O,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US20120309698A1,N#CC1(N)CCC(F)(CO)CC1.O=C(Cl)OCc1ccccc1>>N#CC1(NC(=O)OCc2ccccc2)CCC(F)(CO)CC1,,O,,ClCCl,,test
US20160002215A1,Cc1ccn(-c2cc([N+](=O)[O-])cc(C(F)(F)F)c2)n1>>Cc1ccn(-c2cc(N)cc(C(F)(F)F)c2)n1,[Pd],CO,,,,test
US20030073733A1,O=Cc1cccc(Cl)c1.SCCCS>>Clc1cccc(C2SCCCS2)c1,,ClC(Cl)Cl,,,,test
US20160276592A1,BrCCCCCCc1cc(Br)sc1Br.CC(=O)/C=C/c1ccc(O)cc1>>CC(=O)/C=C/c1ccc(OCCCCCCc2cc(Br)sc2Br)cc1,,CN(C)C=O,Cl,O=C([O-])[O-].[K+].[K+],,test
US20050054696A1,CNN.O=C(O)c1ccccc1>>CN(N)C(=O)c1ccccc1,,CN(C)C=O,O,ClCCCl,On1nnc2ccccc21,test
US20090137454A1,CC(C)(C)OC(=O)C1=CC=CC(O)(C(=O)OC(C)(C)C)C1.COC(=O)CCCCCCCCCBr>>COC(=O)CCCCCCCCCOc1cc(C(=O)OC(C)(C)C)cc(C(=O)OC(C)(C)C)c1,,CC(C)=O,O,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120101110A1,BrBr.COCc1cccc(-c2oc(C)nc2CO)c1>>COCc1cccc(-c2oc(C)nc2CBr)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20080090822A1,C1CCNCC1.CS(=O)(=O)c1ccc(Cl)c(C(=O)N2CCN(c3ccc(Cl)c(Cl)c3)CC2)c1>>CS(=O)(=O)c1ccc(N2CCCCC2)c(C(=O)N2CCN(c3ccc(Cl)c(Cl)c3)CC2)c1,,ClCCl,,CC(C)NC(C)C,,test
US04200641,C=C(C)n1c(=O)n(CCCCCCCl)c2ccccc21.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>O=c1[nH]c2ccccc2n1CCCCCCN1CCN(C(c2ccccc2)c2ccccc2)CC1,,CC(=O)CC(C)C,O,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US04529565,COc1ccc(OC)c(Oc2ccc(C(C)(C)C)cc2)c1>>CC(C)(C)c1ccc(Oc2cc(O)ccc2O)cc1,,c1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20140171446A1,CC(C)[Mg]Cl.COc1ccc(C(=O)c2ccc(-n3c(C)ccc3C)nc2)cc1>>COc1ccc(C(O)(c2ccc(-n3c(C)ccc3C)nc2)C(C)C)cc1,,C1CCOC1,,O,,test
US20090270402A1,BrBr.CC(=O)c1cc(F)c(F)cc1F>>O=C(CBr)c1cc(F)c(F)cc1F,,ClCCl,,,,test
US20150087646A1,COC(=O)c1ccc(-n2nc(-c3cc(CNC(=O)C(F)(F)F)ccc3Cl)[nH]c2=O)cc1OC.Nc1cccc(C(F)(F)F)c1>>COc1cc(-n2nc(-c3cc(CNC(=O)C(F)(F)F)ccc3Cl)[nH]c2=O)ccc1C(=O)Nc1cccc(C(F)(F)F)c1,,Cc1ccccc1,,C[Al](C)C,,test
US20020091138A1,Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc(N)c(C(=O)c2cccc(Cl)c2)c1.O=C(Cl)c1ccccc1.c1ccncc1>>Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc(NC(=O)Cc2ccccc2)c(C(=O)c2cccc(Cl)c2)c1,,ClCCl,,O,,test
US20020183320A1,Cc1ccc(C)c(C=O)c1.Nc1nc[nH]n1.[C-]#[N+]C(C)(C)CC(C)(C)C>>Cc1ccc(C)c(-c2nc3nc[nH]n3c2NC(C)(C)CC(C)(C)C)c1,,[O-][Cl+3]([O-])([O-])O,,,,test
US20140066426A1,COC(=O)C(C)(C)CN(C)C(=O)OC(C)(C)C>>CNCC(C)(C)C(=O)OC,,C1CCOC1,,C1COCCO1,Cl,test
US20090023763A1,N.Nc1cc(-c2ccncn2)c(-c2ccco2)nc1Cl>>Nc1cc(-c2ccncn2)c(-c2ccco2)nc1N,Cl[Cu],,,,,test
US20160214971A1,CCOc1cc(C(=O)O)c(F)cc1-c1cnc(F)c(Cl)c1.CS(N)(=O)=O>>CCOc1cc(C(=O)NS(C)(=O)=O)c(F)cc1-c1cnc(F)c(Cl)c1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20150368246A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4nc(C)n5c6cccc(F)c6cc5c4n3)cc12>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c(-c3ccc4c(n3)-c3cc5c(F)cccc5n3C(C)N4)cc12,,C1CCOC1,CO,[BH4-].[Na+],[Cl-].[NH4+],test
US20110021522A1,CC1(C)OC(=O)CC(=O)O1.Nc1ccccc1C=O>>O=C(O)C1=Cc2ccccc2NC1,,O,,,,test
US20120088770A1,CCOC(CN(Cc1ccccc1)C(=O)[C@H](C)N)OCC.O=C(NCc1ccccc1)Nc1ccsc1C(=O)O>>CCOC(CN(Cc1ccccc1)C(=O)[C@H](C)NC(=O)c1sccc1NC(=O)NCc1ccccc1)OCC,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20090131406A1,C=CCCN(Cc1ccc(C)cc1Br)C(=O)[C@H]1OC(C)(C)O[C@@H]1CC=C>>Cc1ccc(CN2CCC=CC[C@H]3OC(C)(C)O[C@@H]3C2=O)c(Br)c1,,ClCCl,,,,test
US04487945,CC1=CCC2(CC1)OC2(C)C.Sc1ccccc1>>CC1=CCC(O)(C(C)(C)Sc2ccccc2)CC1,,CCCCCO,,[H-].[Na+],,test
US04603011,CC(C)(COC(C(C)(C)C)C(C)(C)C)NC(=O)OCc1ccccc1>>CC(C)(N)COC(C(C)(C)C)C(C)(C)C,[Pd],CO,,,,test
US20080132503A1,COC(=O)CBr.O=Cc1ccc(OCc2ccccc2)cc1O>>COC(=O)c1cc2ccc(OCc3ccccc3)cc2o1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080207654A1,CC(C)OC(=O)N=NC(=O)OC(C)C.CC1(C)CC(O)CCO1.CCCc1nc(CC)n(-c2ccc(O)cc2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1>>CCCc1nc(CC)n(-c2ccc(OC3CCOC(C)(C)C3)cc2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US03949085,CC(C)Br.O=c1c(-c2ccccc2)coc2cc(O)ccc12>>CC(C)Oc1ccc2c(=O)c(-c3ccccc3)coc2c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090264427A1,CCn1c(S)nc(C)c1C.O=[N+]([O-])c1ccc(F)c(Cl)c1>>CCn1c(Sc2ccc([N+](=O)[O-])cc2Cl)nc(C)c1C,,CN(C)C=O,O,[H-].[Na+],,test
US20080312234A1,Cc1cc(CNC(=O)C=Cc2ccc(C(F)(F)F)nc2N2CCOCC2)cc(F)c1NS(C)(=O)=O>>Cc1cc(CNC(=O)CCc2ccc(C(F)(F)F)nc2N2CCOCC2)cc(F)c1NS(C)(=O)=O,[Pd],CO,,,,test
US20100075965A1,C1CCNC1.Nc1ncc(Br)cc1C=O>>Nc1ncc(Br)cc1CN1CCCC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20140249129A1,BrCC1CCOC1.N#Cc1ccc(C2NC(=O)N(c3cccc(C(F)(F)F)c3)C3=C2C(=O)CCC3)cc1>>N#Cc1ccc(C2C3=C(CCCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2CC2CCOC2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04028386,COC(=O)C(C)(C)C(=O)CCC=C(C)CCC=C(C)C.O=C(OO)c1cccc(Cl)c1>>COC(=O)C(C)(C)C(=O)CCC=C(C)CCC1OC1(C)C,,ClCCl,,O=C([O-])O.[Na+],,test
US20020147214A1,Brc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1.CCCC[Sn](CCCC)(CCCC)C1=CCCO1>>C1=C(c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2)OCC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,,,test
US20090042967A1,C[C@H]1[C@H](O[Si](C)(C)C(C)(C)C)C(C)(C)C(=O)N1c1ccc(C#N)c(Cl)c1>>C[C@H]1[C@H](O)C(C)(C)C(=O)N1c1ccc(C#N)c(Cl)c1,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20160157489A1,Cc1cc(Br)c(O)c(Br)n1>>Cc1nc(Br)ccc1O,,O,,C1CCOC1,Cl,test
US20160152626A1,COc1ccc2c(c1)OCCC2=O.O=C1CCC(=O)N1Br>>COc1cc2c(cc1Br)C(=O)CCO2,,CC#N,,CCOCC,,test
US20110124642A1,NN.O=C(O)c1ccccc1C(=O)C(F)(F)F>>O=c1[nH]nc(C(F)(F)F)c2ccccc12,,CCO,,O,,test
US05484942,O=C(OO)c1cccc(Cl)c1.c1ccc(C2(c3ccccc3)CCSC3CNCC32)cc1>>O=S1CCC(c2ccccc2)(c2ccccc2)C2CNCC21,,CO,ClCCl,,,test
US20090181963A1,COC(Cn1nnc2c(N3CCOCC3)nc(-c3ccc(N)cc3)nc21)OC.Cc1ccc(N=C=O)cc1>>COC(Cn1nnc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(C)cc4)cc3)nc21)OC,CN(C)c1ccncc1,ClCCl,,,,test
US20070072896A1,COc1cnc2[nH]cc(-c3cn[nH]c3)c2c1>>Oc1cnc2[nH]cc(-c3cn[nH]c3)c2c1,,ClCCl,,BrB(Br)Br,,test
US20080015199A1,COC(=O)N=C(SC)C(=Nc1ccc(-c2noc(C)n2)cc1)c1cc(OC)c(OC)cc1F.NNc1cccnn1>>COc1cc(F)c(C(Nc2ccc(-c3noc(C)n3)cc2)c2nn(-c3cccnn3)c(=O)[nH]2)cc1OC,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20160168096A1,C1CCNC1.Clc1cccc(Cl)n1>>Clc1cccc(N2CCCC2)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04367238,COc1c(C=O)cccc1Oc1ccccc1C.O=C(O)CC(=O)O>>COc1c(C=CC(=O)O)cccc1Oc1ccccc1C,,c1ccncc1,,C1CCNCC1,,test
US20060135578A1,CCOC(=O)c1cn(Cc2ccccc2)nc1O.COCOc1cc(CO)ccc1OCc1nc(-c2ccco2)oc1C>>CCOC(=O)c1cn(Cc2ccccc2)nc1OCc1ccc(OCc2nc(-c3ccco3)oc2C)c(OCOC)c1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US03976786,CC(=O)OC(C)=O.CCCCNc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>CCCCN(C(C)=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1,O=S(=O)(O)O,,,,,test
US04459422,COC(=O)CC(=O)CC(O)/C=C/c1c(Cl)cc(Cl)cc1OCc1ccccc1>>O=C1CC(O)CC(/C=C/c2c(Cl)cc(Cl)cc2OCc2ccccc2)O1,,CCO,O,Cl,[BH4-].[Na+],test
US20080167368A1,CCNC(=O)Nc1[nH]cc(-c2ccc([N+](=O)[O-])cc2)c1C(N)=O>>CCNC(=O)Nc1[nH]cc(-c2ccc(N)cc2)c1C(N)=O,[Pd],CO,,[H][H],,test
US20120157432A1,CC(C)(C)OC(=O)N1[C@H](Cc2ccc(C(=O)N3CCC4(CCOC4=O)CC3)cc2)CC[C@@H]1[C@H](O)c1ccccc1>>O=C(c1ccc(C[C@@H]2CC[C@H]([C@H](O)c3ccccc3)N2)cc1)N1CCC2(CCOC2=O)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040214888A1,COC(=O)c1cccc(-c2ccc(OC)c(CNC(=O)OC(C)(C)C)c2)c1>>COc1ccc(-c2cccc(CO)c2)cc1CNC(=O)OC(C)(C)C,,C1CCOC1,,Cl,[BH4-].[Li+],test
US20070135479A1,CC(C)(C)OC(=O)N1CCCC(O)C1.Cc1cc2c(N)nccc2cc1O>>Cc1cc2c(N)nccc2cc1OC1CCCN(C(=O)OC(C)(C)C)C1,,CN(C)C=O,CO,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US03956366,CC1(NC(N)=O)CCCCC1.ClCl>>CC1(NC(=O)NCl)CCCCC1,,O,,,,test
US20060270690A1,C#CCN(c1cccc(C(=O)C=CN(C)C)c1)S(C)(=O)=O.Nc1[nH]ncc1C(=O)c1cccs1>>C#CCN(c1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1)S(C)(=O)=O,,CC(=O)O,,CCOC(C)=O,,test
US20100233603A1,Cc1cc(C(C)(C)c2ccc(O)c(C)c2)ccc1O.O=C(Cl)Cl>>Oc1ccc(C(=C(Cl)Cl)c2ccc(O)cc2)cc1,,[K+],[OH-],ClCCl,,test
US20050182130A1,NCCC[C@@H]1OC[C@@H](c2cccc3cc(OCC4CC4)ccc23)CO1.O=C(Cl)Oc1ccc(Cl)cc1>>O=C(NCCC[C@@H]1OC[C@@H](c2cccc3cc(OCC4CC4)ccc23)CO1)Oc1ccc(Cl)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05681958,Br[Mg]c1ccccc1.Cn1c2c3ccccc3nc-2c(Cl)c2cc(F)ccc21>>C[NH+]1C2=c3ccccc3=NC2=C(c2ccccc2)c2cc(F)ccc21.Cl,,C1COCCO1,,CCOCC,,test
US20140275182A1,COC(=O)c1c(C(F)(F)F)ccn1S(=O)(=O)c1ccccc1>>COC(=O)c1[nH]ccc1C(F)(F)F,,CO,,Cl,C[O-].[Na+],test
US20070299068A1,CCOc1ccc2c(C#N)c(-c3ccc(N)cc3)n(C3CCC3)c2c1.NCCO.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCOc1ccc2c(C#N)c(-c3ccc(NC(=O)NCCO)cc3)n(C3CCC3)c2c1,,ClCCl,,c1ccncc1,,test
US20130079321A1,Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2NC(=O)OC(C)(C)C)c1N1CCN[C@@H](C(F)(F)F)C1>>Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCN[C@H](C(F)(F)F)C1,,ClCCl,O=C(O)C(F)(F)F,N,,test
US20150210701A1,CC(=O)SC[C@H]1CN(C(=O)OC(C)(C)C)C[C@@H]1O.Clc1cnccn1>>CC(C)(C)OC(=O)N1C[C@H](O)[C@@H](CSc2cnccn2)C1,,CO,,O,C[O-].[Na+],test
US20160221946A1,O=Cc1c[nH]c2cc(Br)cnc12.O=S(=O)(Cl)c1cccc(F)c1>>O=Cc1cn(S(=O)(=O)c2cccc(F)c2)c2cc(Br)cnc12,,CN(C)C=O,,[H-].[Na+],,test
US20080021043A1,COC(=O)c1ccnc(-c2ccc(C(F)(F)F)cc2)c1.Cl>>COC(=O)[C@H]1CCN[C@@H](c2ccc(C(F)(F)F)cc2)C1.Cl,O=[Pt],C1COCCO1,CO,,,test
US20160272597A1,O=C1c2ccccc2C(=O)N1C[C@H]1CN(c2ccc(F)c(F)c2)C(=O)O1>>NC[C@H]1CN(c2ccc(F)c(F)c2)C(=O)O1,,CO,O,NN,,test
US20090105258A1,C#Cc1ccccc1.CC(NC(=O)OC(C)(C)C)c1ccc(N)c(I)c1>>CC(NC(=O)OC(C)(C)C)c1ccc(N)c(C#Cc2ccccc2)c1,I[Cu]I,C1CCOC1,,,,test
US20120101099A1,CO.O=C(O)c1cccc(CBr)c1>>COC(=O)c1cccc(CBr)c1,,CCOC(C)=O,,O=S(Cl)Cl,,test
US04431653,Cc1ncc[nH]1.O=CN1CCC(CCCBr)CC1>>Cc1nccn1CCCC1CCN(C=O)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20010011135A1,CNC=O.Clc1ccncc1>>CNC(=O)c1cc(Cl)ccn1,,O,,O=S(=O)(O)O,,test
US20020115674A1,C1CCNC1.COc1ccc(-n2c(=O)n(OCc3ccccc3)c(=O)c3cc(F)c(Cl)nc32)cc1>>COc1ccc(-n2c(=O)n(OCc3ccccc3)c(=O)c3cc(F)c(N4CCCC4)nc32)cc1,,CC#N,,CCN(CC)CC,,test
US20160009701A1,CCOC(=O)C1CCc2[nH]c3c(C(N)=O)cc(Br)cc3c2C1>>CCOC(=O)c1ccc2[nH]c3c(C(N)=O)cc(Br)cc3c2c1,,Cc1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20140213586A1,COc1cc(N)cc(OC)c1.O=C(c1c[nH]c2ccc(CCO)cc12)C(Br)c1ccccc1>>COc1cc(NC(C(=O)c2c[nH]c3ccc(CCO)cc23)c2ccccc2)cc(OC)c1,,CC#N,,,,test
US03963745,COc1cc(C(=O)N=[N+]=[N-])cc(OC)c1OC.NC1CCN(Cc2ccccc2)C1>>COc1cc(C(=O)NC2CCN(Cc3ccccc3)C2)cc(OC)c1OC,,c1ccccc1,,CC(C)OC(C)C,,test
US20060100219A1,CNCCC(=O)N(C)CCc1ccc(C2=NCCN2C(=O)OC(C)(C)C)cc1.O=C(O)C(F)(F)F.O=S(=O)(Cl)c1cc(Cl)cc(Cl)c1>>CN(CCc1ccc(C2=NCCN2)cc1)C(=O)CCNCS(=O)(=O)c1cc(Cl)cc(Cl)c1.O=C(O)C(F)(F)F,,CC#N,O,CCN(C(C)C)C(C)C,,test
US20160068532A1,Cc1cc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3cc(N)c(CN[C@H](C)c4ccc(F)cc4)cc23)ccn1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>Cc1cc(-c2nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c3cc4c(cc23)CN([C@H](C)c2ccc(F)cc2)C(=O)N4)ccn1,,C1COCCO1,,,,test
US20040006143A1,CC(C)(C)OC(=O)N(CCc1ccc(-c2ccc(C=O)s2)cc1)C[C@H](O)c1cccc(Cl)c1.OO>>CC(C)(C)OC(=O)N(CCc1ccc(-c2ccc(C(=O)O)s2)cc1)C[C@H](O)c1cccc(Cl)c1,,CC#N,CCOC(C)=O,[Na+].[O-]Cl,,test
US20100152257A1,CC(O)c1ccccc1F.Cc1noc(-c2ccc(Br)cc2)c1C(=O)O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cc1noc(-c2ccc(Br)cc2)c1NC(=O)OC(C)c1ccccc1F,,Cc1ccccc1,,CCN(CC)CC,,test
US20070155805A1,CCOC(=O)COc1ccc(O)cc1CC.COCCC(CCBr)c1sc2cc(C(F)(F)F)ccc2c1C>>CCOC(=O)COc1ccc(OCCC(CCOC)c2sc3cc(C(F)(F)F)ccc3c2C)cc1CC,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05681834,C=COCC.O=C1OC(CO)CN2C1=Cc1ccsc1S2(=O)=O>>CCOC(C)OCC1CN2C(=Cc3ccsc3S2(=O)=O)C(=O)O1,,C1CCOC1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090247618A1,Clc1ccc(OCc2ccccc2)c(OC[C@H]2CO2)c1>>Oc1ccc(Cl)cc1OC[C@H]1CO1,[Pd],CCOC(C)=O,,[H][H],,test
US20050059710A1,C#C[Si](C)(C)C.Nc1ccc(I)cc1F>>C[Si](C)(C)C#Cc1ccc(N)c(F)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOCC,,,,test
US20050250770A1,C1COCCN1.O=[N+]([O-])c1cnc2nc(Cl)nc(Cl)c2c1>>O=[N+]([O-])c1cnc2nc(Cl)nc(N3CCOCC3)c2c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20030225076A1,Cc1cc(I)ccc1N1COC(=O)c2cc(C(=O)O)c(F)c(F)c21.O=C(Oc1c(F)c(F)c(F)c(F)c1F)C(F)(F)F>>Cc1cc(I)ccc1N1COC(=O)c2cc(C(=O)Oc3c(F)c(F)c(F)c(F)c3F)c(F)c(F)c21,,CCOC(C)=O,CN(C)C=O,c1ccncc1,,test
US05098904,FC(F)(F)c1ncc(OCc2ccccc2)c(Cl)n1.O=C1CCCN1CC1CCNCC1>>O=C1CCCN1CC1CCN(c2nc(C(F)(F)F)ncc2OCc2ccccc2)CC1,,CC#N,,O,O=C([O-])[O-].[Na+].[Na+],test
US20070190160A1,C=CC(=O)OCCO.CN(C)c1cccc2c(S(=O)(=O)Cl)cccc12>>C=CC(=O)OCCOS(=O)(=O)c1cccc2c(N(C)C)cccc12,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04877895,COS(=O)(=O)OC.N#CN.N#Cc1ccc(N=C=S)cc1>>CSC(=NC#N)Nc1ccc(C#N)cc1,,CCO,,[Na],,test
US20160024009A1,CCN([C@@H](CO)C(=O)OC)S(=O)(=O)c1ccc(F)c(F)c1>>C=C(C(=O)O)N(CC)S(=O)(=O)c1ccc(F)c(F)c1,,C1COCCO1,,[Na+].[OH-],,test
US20120258953A1,CC(C)(C)OC(=O)N1CCNC(c2ccccc2)C1.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)C(c2ccccc2)C1,,C1COCCO1,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20090131468A1,COc1cc(C(=O)NS(=O)(=O)c2ccccc2S(N)(=O)=O)ccc1Br>>NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(Br)c(O)c1,,ClCCl,,BrB(Br)Br,,test
US20070197609A1,Cc1cc(C2CCCN2C(=O)OCc2ccccc2)nc(-n2ccnc2)n1>>Cc1cc(C2CCCN2)nc(-n2ccnc2)n1,[Pd],CCO,,,,test
US20080300282A1,CCc1ccc(C(O)COc2ccc(C=O)cc2)nc1.O=S(Cl)Cl>>CCc1ccc(C(Cl)COc2ccc(C=O)cc2)nc1,,ClC(Cl)Cl,,O,,test
US05585373,O=C(CBr)OCc1ccccc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>O=C(C=P(c1ccccc1)(c1ccccc1)c1ccccc1)OCc1ccccc1,,c1ccccc1,,,,test
US04608079,COC(=O)c1cc2ccsc2nc1C(=O)OC>>O=C(O)c1cc2ccsc2nc1C(=O)O,,CO,,O,[K+].[OH-],test
US20020013358A1,Br.CN1CCC[C@@H]1Cc1c[nH]c2ccc(CCS(=O)(=O)c3ccccc3)cc12.O>>Br.CN1CCC[C@@H]1Cc1c[nH]c2ccc(CCS(=O)(=O)c3ccccc3)cc12.O,,CC(C)=O,O,,,test
US04743585,O=C1CC(C(=O)OCc2ccccc2)C(=O)C(Cc2ccccc2)N1>>O=C1CCC(=O)C(Cc2ccccc2)N1,[Pd],CCOC(C)=O,,[H][H],,test
US20040053908A1,COc1cc2nccc(Oc3ccc4[nH]ccc4c3)c2cc1OC.O=C(Nc1nccs1)Oc1ccccc1>>COc1cc2nccc(Oc3ccc4c(ccn4C(=O)Nc4nccs4)c3)c2cc1OC,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US07816386B2,CCOC(=O)Cl.O=C(/C=C/c1cccc(C=NOCCN2CCOCC2)c1)NOC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cl.O=C(/C=C/c1cccc(C=NOCCN2CCOCC2)c1)NO,,C1CCOC1,,,,test
US20160031825A1,CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)O.CC(C)(C)OC(=O)N1CCNCC1.CN(C)C=O>>CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US20020156081A1,Brc1ccc(Nc2noc3ccccc23)cc1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(c2ccc(Nc3noc4ccccc34)cc2)OC1(C)C,,CN(C)C=O,,ClCCl,CC(=O)[O-].[K+],test
US20100130446A1,C=C[Mg]Br.CON(C)C(=O)C(CC1CCOCC1)c1ccc(SC)c(F)c1>>C=CC(=O)C(CC1CCOCC1)c1ccc(SC)c(F)c1,,C1CCOC1,,Cl,,test
US04463007,CCOC(=O)c1nc2c3ccccc3nc(=O)n2[nH]1.CI>>CCOC(=O)c1nc2c3ccccc3n(C)c(=O)n2n1,,CN(C)C=O,,[H-].[Na+],,test
US20040077605A1,CC(=O)Nc1ccc(O)cc1.Cc1ccc(CCO)o1>>Cc1ccc(CCOc2ccc(CC(N)=O)cc2)o1,,C1CCOC1,ClCCl,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110034450A1,CC(C)C1=NC(CCC(=O)OC(C)(C)C)(C(F)(F)F)OC1=O.NN>>O=C1CCC(C(F)(F)F)=NN1,,CC(=O)O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20060247210A1,CN1CCNCC1.Cc1n[nH]c(N)c1-c1nc2ccc(S(=O)(=O)Cl)cc2s1>>Cc1n[nH]c(N)c1-c1nc2ccc(S(=O)(=O)N3CCN(C)CC3)cc2s1,,CCN(CC)CC,,,,test
US20140371073A1,C#C[Si](C)(C)C.COC(=O)CCC(=O)Nc1cnc(Br)cn1>>COC(=O)CCC(=O)Nc1cnc(C#C[Si](C)(C)C)cn1,I[Cu]I,C1CCOC1,,CC(C)NC(C)C,,test
US04578378,C1CCOC1.CCN(CC)CC.CNC(=O)CS>>CN1C(=O)CSCC1CC#N,,O,,,,test
US20040157904A1,COC(=O)C(F)(F)Cl.COC(=O)c1cc(O)ccc1Br>>COC(=O)c1cc(OC(F)F)ccc1Br,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030199422A1,CC(C)=CCC/C(C)=C/CO.COC(=O)c1ccc(N)cc1>>CC(C)=CCCC(C)=CCOC(=O)c1ccc(N)cc1,,Cc1ccccc1,,CO,[H-].[Na+],test
US20120116095A1,C1CCOC1.Cn1cnc(C(=O)NCc2ccc(F)c(Br)c2)c1>>CCCN(Cc1ccc(F)c(Br)c1)C(=O)c1cn(C)cn1,,O,,[H-].[Na+],,test
US20090176804A1,CO.O=C(Cl)C(=O)Cl.O=S(=O)(Cc1cccc(Cl)c1)Nc1cc(-c2cc3ccccc3[nH]2)ccc1Cl>>COC(=O)C(=O)c1c(-c2ccc(Cl)c(NS(=O)(=O)Cc3cccc(Cl)c3)c2)[nH]c2ccccc12,,ClCCl,,,,test
US20020049344A1,CN(C)C(=O)C1(c2ccccc2)CC1.[Li]C>>CC(=O)C1(c2ccccc2)CC1,,C1CCOC1,,[Cl-].[NH4+],,test
US20080119518A1,COc1ccc(CC#CO)cc1CC1COC(C)(C)O1>>COc1ccc(CCCO)cc1CC1COC(C)(C)O1,[Pd],CCOC(C)=O,,,,test
US05683963,CC(=O)O[C@@H]1[C@@H](CO)O[C@]2(C(=O)NC(=O)N2C(C)=O)[C@@H]1OC(C)=O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(=O)O[C@@H]1[C@@H](COS(=O)(=O)C(F)(F)F)O[C@]2(C(=O)NC(=O)N2C(C)=O)[C@@H]1OC(C)=O,,CCOC(C)=O,ClCCl,c1ccncc1,,test
US20100094000A1,Cc1nn(CC(F)(F)COC(=O)CNC(=O)OC(C)(C)C)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2.Cl>>Cc1nn(CC(F)(F)COC(=O)CN)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2.Cl,,CCOC(C)=O,,,,test
US20070275984A1,O=C1CCC(=O)N1Br.OCc1cc2c(NCCc3ccccc3)ncnc2s1>>BrCc1cc2c(NCCc3ccccc3)ncnc2s1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150057309A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.Clc1ccc2nnn(Cc3ccc4ncccc4c3)c2n1>>CC(=O)c1ccc2nnn(Cc3ccc4ncccc4c3)c2n1,[Pd],Cc1ccccc1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20030130318A1,C1COCCN1.Cc1c(Cl)cccc1S(=O)(=O)Nc1ncc(CC(=O)O)s1>>Cc1c(Cl)cccc1S(=O)(=O)Nc1ncc(CC(=O)N2CCOCC2)s1,CN(C)c1ccncc1,CN(C)C=O,ClCCl,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US20130079328A1,Cc1cc(CN)cnc1-c1ccnc(F)c1.O=C(O)c1ccc(-c2cccc(F)c2)cn1>>Cc1cc(CNC(=O)c2ccc(-c3cccc(F)c3)cn2)cnc1-c1ccnc(F)c1,,CN(C)C=O,CS(C)=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040006143A1,COC(=O)c1ccc(-c2ccc(CCNC(=O)OCc3ccccc3)cc2)c(C)c1>>COC(=O)c1ccc(-c2ccc(CCN)cc2)c(C)c1,[Pd],CO,O,O=C[O-].[NH4+],,test
US20150376174A1,C=C(C)CBr.CCOC(=O)c1sc(-c2ccc(O)c(-n3cnnn3)c2)nc1C>>CCOC(=O)c1sc(-c2ccc(OC=C(C)C)c(-n3cnnn3)c2)nc1C,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20060149063A1,CCCCCCCCCCCCCCCCCC(=O)CC(=O)OCC.N=C(N)NC(=N)Nc1ccccc1>>CCCCCCCCCCCCCCCCCc1cc(=O)[nH]c(NC(=N)Nc2ccccc2)n1,,CCO,,,,test
US20070254877A1,CN(C)C(N(C)C)N(C)C.O=C1CCCCc2c1[nH]c1ccccc21>>CN(C)C=C1CCCc2c([nH]c3ccccc23)C1=O,,O,,CN(C)C=O,,test
US20120035214A1,COCCCc1ccccc1-c1ccc([C@@H]2C(=O)NC(=O)C[C@H]2c2ccccc2)c(C)c1>>COCCCc1ccccc1-c1ccc([C@@H]2CNCC[C@H]2c2ccccc2)c(C)c1,,CO,,ClCCl,,test
US04259340,BrBr.COc1cc(OC)c(C(=O)O)cc1C(C)=O>>COc1cc(OC)c(C(=O)CBr)cc1C(=O)O,,C1COCCO1,,,,test
US20130274241A1,CN1CC=C(c2ccc3[nH]nc(-c4cn(-c5ccc(C(=O)N6CCOCC6)cc5)nn4)c3c2)CC1>>CN1CCC(c2ccc3[nH]nc(-c4cn(-c5ccc(C(=O)N6CCOCC6)cc5)nn4)c3c2)CC1,[Pd],CO,,,,test
US20100331314A1,CN1CCN(c2cccc(Nc3ccn4ncc(C=O)c4n3)c2)CC1.O=C1CNC(=O)N1>>CN1CCN(c2cccc(Nc3ccn4ncc(C=C5NC(=O)NC5=O)c4n3)c2)CC1,,CCO,,C1CCNCC1,,test
US20050054640A1,CC(C)(C)OC(=O)NNc1c([N+](=O)[O-])cnc2cc(OCc3ccccc3)ccc12>>CC(C)(C)OC(=O)NNc1c(N)cnc2cc(OCc3ccccc3)ccc12,[Pt],CC#N,CO,,,test
US20110105463A1,CCOC(=O)C1CCOc2cc(Oc3ccc(C(=O)O)cc3)c(Cl)cc21.NC(CO)Cc1ccc(Cl)cc1>>CCOC(=O)C1CCOc2cc(Oc3ccc(C(=O)NC(CO)Cc4ccc(Cl)cc4)cc3)c(Cl)cc21,CN(C)C=O,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20160229860A1,CC(C)(C)OC(=O)Nc1ccc(C#Cc2cnc3ccc(-c4ccc(C(=O)N5CCOCC5)cc4)nn23)cn1>>Nc1ccc(C#Cc2cnc3ccc(-c4ccc(C(=O)N5CCOCC5)cc4)nn23)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050208582A1,CC(=O)O.N#Cc1cc2c(-c3ccc4ccccc4c3)n[nH]c2s1.O=S(=O)(O)O>>O=C(O)c1cc2c(-c3ccc4ccccc4c3)n[nH]c2s1,,O,,,,test
US20150057286A1,COc1ccc2nccc(C)c2c1.O=C1CCC(=O)N1Br>>COc1ccc2nccc(C)c2c1Br,,O=S(=O)(O)O,,O,[Na+].[OH-],test
US20150374849A1,C=CCBr.CC(C)(C)OC(=O)NCCCCC(=O)O>>C=CCN(CCCCC(=O)O)C(=O)OC(C)(C)C,,C1CCOC1,,[H-].[Na+],,test
US20110065681A1,Brc1ccccn1.CCOC(=O)c1cc(C=O)cc(-c2ccc(C)cc2)c1>>CCOC(=O)c1cc(-c2ccc(C)cc2)cc(C(O)c2ccccn2)c1,,C1CCOC1,,II,[Mg],test
US20030097010A1,CCCCCCCCCCCCc1ccc(C(=O)c2cc(C(=O)O)c(C(=O)c3ccc(CCCCCCCCCCCC)cc3)cc2C(=O)O)cc1>>CCCCCCCCCCCCc1ccc(Cc2cc(C(=O)O)c(Cc3ccc(CCCCCCCCCCCC)cc3)cc2C(=O)O)cc1,[Pd],C1CCOC1,,[H][H],,test
US20050020566A1,CC(=O)c1ccc(CO)s1.CC(C)(C)[Si](C)(C)Cl>>CC(=O)c1ccc(CO[Si](C)(C)C(C)(C)C)s1,,CN(C)C=O,,c1c[nH]cn1,,test
US20100197634A1,COc1nccc2c(Nc3c(Cl)cc(C#C[Si](C)(C)C)cc3Cl)nc3ccncc3c12>>C#Cc1cc(Cl)c(Nc2nc3ccncc3c3c(OC)nccc23)c(Cl)c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20100267697A1,CC(C)(C)OC(=O)N(Cc1ccc(I)cc1)c1ccc(F)cc1.NC1CC1>>CC(C)(C)OC(=O)N(Cc1ccc(NC2CC2)cc1)c1ccc(F)cc1,[Cu]I,CS(C)=O,O,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US20160244451A1,COC(=O)c1cc(F)c(N)cc1F.O=S(=O)(Cl)c1ccc(Br)cc1>>COC(=O)c1cc(F)c(NS(=O)(=O)c2ccc(Br)cc2)cc1F,,ClCCl,,c1ccncc1,,test
US20040198982A1,COC(=O)C(Br)CC(C)C.Nc1ncc(Br)cn1>>COC(=O)C(CC(C)C)Nc1ncc(Br)cn1,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20100130492A1,CC1(C)CNCCN1.Nc1ncc(-c2nc(N3CCOCC3)c3nc(Cl)n(CC(F)(F)F)c3n2)cn1>>CC1(C)CN(c2nc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3n2CC(F)(F)F)CCN1,,CO,ClCCl,CN1CCCC1=O,,test
US04497817,CC(=O)Nc1ccc2c(c1)sc1nc(-c3ccccc3)cn12>>Nc1ccc2c(c1)sc1nc(-c3ccccc3)cn12,,COCCO,,Cl,O,test
US20010021713A1,CC(C)(C)OC(=O)NC(=N)N(OCCNC(=O)OCc1ccccc1)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NC(=N)N(OCCN)C(=O)OC(C)(C)C,[Pd],C1CCOC1,CCO,,,test
US06255496B1,CC(=O)O.O=C(O)CCc1ccc(OCCSCCO)cc1>>CC(=O)OCCSCCOc1ccc(CCC(=O)O)cc1,,CC(=O)O,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US20090131472A1,CC(C)(C)N1CC=C([Sn](C)(C)C)CC1.O=c1ccn2c(Cl)cc(Br)cc2c1-c1c(Cl)cccc1Cl>>CC(C)(C)N1CC=C(c2cc(Cl)n3ccc(=O)c(-c4c(Cl)cccc4Cl)c3c2)CC1,,C1CCOC1,,,,test
US20160243100A1,CC(=O)c1cc(NC(=O)OC(C)(C)C)ccn1>>CC(=O)c1cc(N)ccn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090111983A1,C1CSCN1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C1(N)CCCCC1>>O=C(NC1(C(=O)O)CCCCC1)N1CCSC1,,ClCCl,,CCN(CC)CC,,test
US20030028022A1,CC(C)(C)OC(=O)n1c(CNC2CCCc3cccnc32)nc2ccccc21.O=Cc1ccncc1>>c1cnc2c(c1)CCCC2N(Cc1ccncc1)Cc1nc2ccccc2[nH]1,,ClCCl,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],,test
US20110280940A1,COC(=O)Cl.COc1cc(C(=O)O)ccc1O>>COC(=O)Oc1ccc(C(=O)O)cc1OC,,O,,[Na+].[OH-],,test
US03940403,CCOC(=O)CCc1cnc(Oc2ccccc2)cc1C(=O)O.O=S(Cl)Cl>>CCOC(=O)CCc1cnc(Oc2ccccc2)cc1C(=O)Cl,,CN(C)C=O,,,,test
US20070161615A1,CC(=O)N1CCNCC1.O=[N+]([O-])c1ccc(F)c(Cl)c1>>CC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2Cl)CC1,,CCOC(C)=O,O,,,test
US20070135467A1,NC(=S)N[C@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1.O=C1CCCC1>>Fc1cc(OC(F)(F)C(F)F)cc([C@@](Cc2ccccc2)(Nc2nc3c(s2)CCC3)c2ccc(Cl)cn2)c1,,CCO,,BrBr,,test
US06258360B1,CC(C)(C)[Si](C)(C)Cl.Cc1c(O)c(=O)c1=O>>Cc1c(O[Si](C)(C)C(C)(C)C)c(=O)c1=O,,CN(C)C=O,,O,c1c[nH]cn1,test
US20050171149A1,Cc1cc(C=CC(=O)c2ccc(Cl)cc2O)cc(C)c1O>>Cc1cc(-c2cc(=O)c3ccc(Cl)cc3o2)cc(C)c1O,,CS(C)=O,,II,,test
US20020169146A1,CC(N)c1ccccc1.CCOC(Cc1ccc(OCCN2c3ccccc3Sc3ccccc32)cc1)C(=O)O>>CCNc1ccccc1.CCOC(Cc1ccc(OCCN2c3ccccc3Sc3ccccc32)cc1)C(=O)O,,Cc1ccccc1,,,,test
US20140243322A1,Cc1ccc(B(O)O)cc1.Cc1noc(C)c1I>>Cc1ccc(-c2c(C)noc2C)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20060183736A1,CC(C)(C)C(=O)Oc1ccc2c(Br)c(Br)sc2c1>>Oc1ccc2c(Br)c(Br)sc2c1,,CCO,,[K+].[OH-],,test
US20160244429A1,Cc1ccc(S(=O)(=O)OCCCCc2c[nH]c3ccc(C#N)cc23)cc1.O=C1COCCN1c1ccc(N2CCNCC2)cc1>>N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc(N5CCOCC5=O)cc4)CC3)c2c1,,CC#N,,[I-].[K+],,test
US20130131035A1,CNC(=O)c1cccc(N)c1.Clc1cc(Cl)ncn1>>CNC(=O)c1cccc(Nc2cc(Cl)ncn2)c1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20140256715A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.Cn1nc(Nc2cccc(C3(C)COCC(=O)N3)c2)c2ccc(Br)cc21>>Cn1nc(Nc2cccc(C3(C)COCC(=S)N3)c2)c2ccc(Br)cc21,,Cc1ccccc1,,,,test
US20020147192A1,CC(C)(C)OC(=O)NCc1ccc(CN(C2CCc3cccnc3C2)S(=O)(=O)c2ccccc2[N+](=O)[O-])cc1>>NCc1ccc(CN(C2CCc3cccnc3C2)S(=O)(=O)c2ccccc2[N+](=O)[O-])cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05314903,ClCc1ccc(Cl)cc1.Nc1nc2ccccc2[nH]1>>Nc1nc2ccccc2n1Cc1ccc(Cl)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050054662A1,COc1cc(OC2CCNCC2)c2c(Nc3ccc(F)c(Cl)c3)ncnc2c1.CS(=O)(=O)Cl>>COc1cc(OC2CCN(S(C)(=O)=O)CC2)c2c(Nc3ccc(F)c(Cl)c3)ncnc2c1,,ClCCl,,CCN(CC)CC,,test
US20100216788A1,Cc1cc(N)ccc1Oc1cccc(OC(F)(F)C(F)F)c1.O=C(OCCn1ccc2ncnc(Cl)c21)c1ccccc1>>Cc1cc(Nc2ncnc3ccn(CCO)c23)ccc1Oc1cccc(OC(F)(F)C(F)F)c1,,CC(C)O,,[Na+].[OH-],,test
US20050037977A1,CN[C@H](C(=O)N[C@H](C(=O)N(C)[C@H](/C=C(\C)C(=O)O)C(C)C)C(C)(C)C)C(C)(C)c1ccccc1.OCc1ccc(OCc2ccccc2)cc1>>CN[C@H](C(=O)N[C@H](C(=O)N(C)[C@@H](/C=C(\C)C(=O)OCc1ccc(OCc2ccccc2)cc1)C(C)C)C(C)(C)C)C(C)(C)c1ccccc1,,ClCCl,,CN(C)c1ccccn1,,test
US20100168080A1,COC(=O)COc1ccc(Cl)cc1NC(N)=O>>NC(=O)Nc1cc(Cl)ccc1OCC(=O)O,,C1CCOC1,O,[Li+].[OH-],,test
US08217069B2,CN.COc1ccc(F)c(F)c1COc1cc(-n2c(=O)[nH]c3c(OC)nc(C)nc32)c(Cl)cc1OCC(=O)O>>CNC(=O)COc1cc(Cl)c(-n2c(=O)[nH]c3c(OC)nc(C)nc32)cc1OCc1c(OC)ccc(F)c1F,,C1CCOC1,,Cl,O=C(n1ccnc1)n1ccnc1,test
US20140135316A1,Cc1nnc2n1-c1ccccc1N(c1ccc(Cl)cc1)C(=O)C21CC1C(=O)[O-]>>Cc1nnc2n1-c1ccccc1N(c1ccc(Cl)cc1)CC21CC1CO,,C1CCOC1,,B,,test
US20140155381A1,COC(=O)Cc1ncc(O)cc1F.II>>COC(=O)Cc1nc(I)c(O)cc1F,,O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20100152272A1,COC(=O)C(C)c1ccc2cc(O)ccc2c1.COC(=O)CCCCCBr>>COC(=O)CCCCCOc1ccc2cc(C(C)C(=O)OC)ccc2c1,,CC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US04278802,COC(=O)C(C)(SC)c1ccc2cc(OC)ccc2c1>>COC(=O)C(C)c1ccc2cc(OC)ccc2c1,[Ni],CO,,,,test
US20100256097A1,C#Cc1ccc(Br)cc1.C[Si](C)(C)N=[N+]=[N-]>>Brc1ccc(-c2c[nH]nn2)cc1,,CC(C)(C)O,O,O=C(CO)O[CH][C@@H](O)CO,C[O-].[Na+],test
US20160184318A1,Cc1nnc(C2CCNCC2)o1.Cc1nnn(Cc2cc(Cl)ccc2COC(=O)n2ccnc2)n1>>Cc1nnn(Cc2cc(Cl)ccc2COC(=O)N2CCC(c3nnc(C)o3)CC2)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20160108156A1,CC(C)(C)CC(C)(C)c1ccc(OC2CCCCO2)c(I)c1.CC(C)(C)c1ccc2c(c1)[nH]c1cc(C(C)(C)C)ccc12>>CC(C)(C)CC(C)(C)c1ccc(OC2CCCCO2)c(-n2c3cc(C(C)(C)C)ccc3c3ccc(C(C)(C)C)cc32)c1,[Cu]I,Cc1ccccc1,,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20120142659A1,CN[C@H](CN1CC(O)C1)C1CCC1.O=C(O)c1ccc(F)cc1Cl>>CN(C(=O)c1ccc(F)cc1Cl)[C@H](CN1CC(O)C1)C1CCC1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20080287462A1,N#Cc1ncccc1Br.O=C(Cl)c1cccc(Br)c1>>N#Cc1ncccc1C(=O)c1cccc(Br)c1,[Zn],C1CCOC1,,,,test
US20070190071A1,CCCCOc1nc(N)c2[nH]c(=O)n(CCCCN(CC(C)(C)CN(C)C)S(=O)(=O)c3cccc(CC(=O)OC)c3)c2n1>>CCCCOc1nc(N)c2[nH]c(=O)n(CCCCN(CC(C)(C)CN(C)C)S(=O)(=O)c3cccc(CC(=O)O)c3)c2n1,,O,,C1CCOC1,[Li+].[OH-],test
US20120264737A1,Brc1ccc(Br)nc1.CC(C)(C)OC(=O)N1CCC(=O)CC1>>CC(C)(C)OC(=O)N1CCC(O)(c2ccc(Br)nc2)CC1,,C1CCOC1,,[Li]CCCC,,test
US20110224241A1,BrBr.CC(C)(C)OC(=O)c1csnc1-c1ccc(Cl)cc1>>CC(C)(C)OC(=O)c1c(-c2ccc(Cl)cc2)nsc1Br,,C1CCOC1,,[Li]CCCC,,test
US20110070270A1,CCO.O=C(O)C=Cc1cccc(C(F)(F)F)c1>>COC(=O)CCc1cccc(C(F)(F)F)c1,[Pd],,,,,test
US20020068721A1,CCOP(=O)(OCC)C(=C1C=CC(NC(=O)C(F)(F)F)=CC1)P(=O)(OCC)OCC>>CCOP(=O)(OCC)C(=C1C=CC(N)=CC1)P(=O)(OCC)OCC,,[Na+],[OH-],,,test
US20150218124A1,COc1cc(C#N)c(Br)c(C#N)c1OC(C)=O.O=C(O)c1ccc(S)cc1>>COc1cc(C#N)c(Sc2ccc(C(=O)O)cc2)c(C#N)c1O,[Zn],CN(C)C=O,,ClCCl,O,test
US20160229816A1,CC(Cl)OC(=O)OC(C)(C)CC(=O)OCc1ccccc1.N#Cc1[nH]nnc1-c1ccc(-c2nccc(C(F)(F)F)n2)cc1>>CC(OC(=O)OC(C)(C)CC(=O)OCc1ccccc1)n1nc(C#N)c(-c2ccc(-c3nccc(C(F)(F)F)n3)cc2)n1,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US20060148858A1,CCOC(=O)/C=C/c1cn(-c2ccc(Cl)cn2)nc1C(C)C>>CCOC(=O)CCc1cn(-c2ccc(Cl)cn2)nc1C(C)C,O=[Pt],CCO,,,,test
US20140128429A1,CC1(C)C(=O)N(Br)C(=O)N1Br.CCC(C)n1ccnc1>>CCC(C)n1cncc1Br,,ClCCl,,O=S([O-])[O-].[Na+].[Na+],,test
US06350749B1,CC(=O)CCl.O=C1CC(=O)CC(c2c(Cl)cccc2Cl)C1>>Cc1coc2c1C(=O)CC(c1c(Cl)cccc1Cl)C2,,CN(C)C=O,,[H-].[Na+],,test
US20120178761A1,COC(=O)C1CN(Cc2ccccc2)CC1(C)c1ccc(Cl)cc1>>CC1(c2ccc(Cl)cc2)CN(Cc2ccccc2)CC1C(=O)O,,C1CCOC1,,CO,[Li+].[OH-],test
US20090163512A1,CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(Cl)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)OC>>CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(Cl)ccc2C)C12C(=O)Nc1cc(Cl)ccc12)C(=O)O,,CO,,O,[Li+].[OH-],test
US04551448,O=[N+]([O-])c1ccc(OC(F)(F)C(F)Br)cc1>>Nc1ccc(OC(F)(F)C(F)Br)cc1,[Pd],CCOC(C)=O,,,,test
US20060270686A1,CB(O)O.COC(=O)Nc1cc(C(=O)c2cc(C)nc(Cl)c2)cc(-c2cccc3c2ccn3[Si](C(C)C)(C(C)C)C(C)C)c1>>COC(=O)Nc1cc(C(=O)c2cc(C)nc(C)c2)cc(-c2cccc3c2ccn3[Si](C(C)C)(C(C)C)C(C)C)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20110028445A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC12CCNC(Cc3cc(O)c(O)cc31)C2(C)C>>CC(C)(C)OC(=O)N1CCC2(C)c3cc(O)c(O)cc3CC1C2(C)C,,ClCCl,,CCN(CC)CC,,test
US04978476,O=C(n1c(-c2ccc(CBr)cc2)nc2ccccc21)C(F)(F)F>>BrCc1ccc(-c2nc3ccccc3[nH]2)cc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20040102456A1,Br.CNC(C)C#N.O=C(Br)C(=O)Br>>Cc1c(Br)nc(Br)c(=O)n1C,CN(C)C=O,ClCCl,ClCCl,,,test
US20050176775A1,CC(C)(C)OC(=O)NCc1cc(F)c(-n2ccc(OCc3ccc(F)cc3F)c(Cl)c2=O)c(F)c1.Cl>>Cl.NCc1cc(F)c(-n2ccc(OCc3ccc(F)cc3F)c(Cl)c2=O)c(F)c1,,C1CCOC1,,,,test
US20120264739A1,CC(C)(C)OC(=O)Nc1cc(Cl)nc(Cl)c1[N+](=O)[O-].NCc1ccc2ncccc2c1>>CC(C)(C)OC(=O)Nc1cc(Cl)nc(NCc2ccc3ncccc3c2)c1[N+](=O)[O-],,CC#N,CCN(CC)CC,,,test
US20100197960A1,CC(C)OB(OC(C)C)OC(C)C.Ic1ccccc1I>>OB(O)c1ccccc1I,,C1CCOC1,CCOCC,CC(C)[Mg]Cl,Cl,test
US05972975,Cc1cc(N)ncc1Br.N#C[Cu]>>Cc1cc(N)ncc1C#N,,CN(C)C=O,O,[C-]#N.[Na+],,test
US20130143864A1,CC(C)(C)OC(=O)N1CCC(O)(c2ccc(OC(F)(F)F)cc2)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccc(OC(F)(F)F)cc2)CC1,,ClCCl,,,,test
US20150111876A1,CC(=O)OC(C)=O.Cc1nc(CN2CCNCC2(C)C)c2cc(C3CCC(C)(C)CC3)sc2n1.ClCCl>>CC(=O)N1CCN(Cc2nc(C)nc3sc(C4CCC(C)(C)CC4)cc23)C(C)(C)C1.Cl,,O,,c1ccncc1,,test
US04517202,CC(=O)OC1CCC2C(C=O)CCC12.CCCCCC(=O)CP(=O)(OC)OC>>CCCCCC(=O)/C=C/C1CCC2C(OC(C)=O)CCC12,,C1CCOC1,CCOCC,CC(=O)O,[Na],test
US20140213586A1,CCOP(=O)(CC(=O)OC)OCC.O=Cc1ccc2[nH]ccc2c1>>COC(=O)C=Cc1ccc2[nH]ccc2c1,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20020042411A1,CS(C)=O.Cc1ccc(NC(=O)c2ccsc2Br)c(O)c1>>Cc1ccc2c(c1)Oc1sc(C)cc1C(=O)N2,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100256092A1,COC(=O)CCC(=O)c1ccc(OC2CCCCO2)cc1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)CCC(=O)c1ccc(OC2CCCCO2)cc1OS(=O)(=O)C(F)(F)F,,ClCCl,O,CCN(CC)CC,,test
US20050065155A1,CC(C)(C)OC(=O)OC(C)(C)C.OCC1CCCNC1>>CC(C)(C)OC(=O)N1CCCC(CO)C1,,C1CCOC1,,CCN(CC)CC,,test
US05969138,COCCN1CCN(C[C@H]2CCN(c3ccc(Cl)cc3)C2=O)CC1.O.O=S(=O)(O)c1ccccc1>>COCCN1CCN(C[C@H]2CCN(c3ccc(Cl)cc3)C2=O)CC1.O.O=S(=O)(O)c1ccccc1,,CCO,,,,test
US20030216444A1,COc1cc(C)ccc1OCc1ccccc1.O=C1CCC(=O)N1Br>>COc1cc(C)c(Br)cc1OCc1ccccc1,,CN(C)C=O,,,,test
US20090093472A1,CC(C)(C)OC(=O)N1CCC[C@@H]1c1[nH]ncc1Cc1ccc(Cl)cc1.O=C=Nc1ccc(C(F)(F)F)cc1>>O=C(Nc1ccc(C(F)(F)F)cc1)N1CCC[C@@H]1c1[nH]ncc1Cc1ccc(Cl)cc1,,C1COCCO1,Cl,CCN(C(C)C)C(C)C,,test
US04699928,C/C(=C\F)CN1C(=O)c2ccccc2C1=O.NC(=O)CCC(=O)NBr>>O=C1c2ccccc2C(=O)N1C/C(=C/F)CBr,,ClC(Cl)(Cl)Cl,,,,test
US20140213580A1,COCCC(=O)N1CCN(c2nc(C3CC3)c(Br)cc2C#N)C[C@H]1C.Nc1ccncc1>>COCCC(=O)N1CCN(c2nc(C3CC3)c(Nc3ccncc3)cc2C#N)C[C@H]1C,,C1COCCO1,,CC(C)c1cc(C(C)C)c(-c2ccccc2P(C2CCCCC2)C2CCCCC2)c(C(C)C)c1,O=C([O-])[O-].[Cs+].[Cs+],test
US20110301181A1,BrBr.Cn1nc(C2CC2)cc1C(=O)O>>Cn1nc(C2CC2)c(Br)c1C(=O)O,,CC(=O)O,,,,test
US20040023971A1,CC(C)(C)OC(=O)NC(CCOc1ccc(C#N)cc1)CN1C2CCC1CNC2.CCCCN=C=O>>CCCCNC(=O)N1CC2CCC(C1)N2CC(N)CCOc1ccc(C#N)cc1,,CC#N,,CCN(CC)CC,,test
US20060040999A1,COc1ccc(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CNC[C@H](N)c1ccccc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CN1C[C@@H](c2ccccc2)NC1=O,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US06011050,CCOc1cc(C(N)CS(C)(=O)=O)ccc1OC.COc1cccc2c1C(=O)OC2=O>>CCOc1cc(C(CS(C)(=O)=O)N2C(=O)c3cccc(OC)c3C2=O)ccc1OC,,CC(=O)O,,,,test
US20100305096A1,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C3(OC)CN(C(=O)CO)C3)n(C)c2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C3(OC)CN(CCO)C3)n(C)c2n1,,C1CCOC1,,,,test
US09090610B2,CC1(C)C(=O)Nc2nc(-c3nn(CC4CCCC4)c4ncc(F)cc34)nc(I)c21>>CC1(C)C(=O)Nc2nc(-c3nn(CC4CCCC4)c4ncc(F)cc34)ncc21,[Pd],CN(C)C=O,,[H][H],,test
US20100216746A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2[nH]1>>CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2n1C(=O)OC(C)(C)C,CN(C)c1ccncc1,C1CCOC1,,,,test
US20110021500A1,FC(F)(F)CNCCc1ccccc1.O=C(Cl)c1cc(Cl)ncn1>>O=C(c1cc(Cl)ncn1)N(CCc1ccccc1)CC(F)(F)F,,CCO,ClCCl,[Na+].[OH-],,test
US20040127492A1,CC[SiH](CC)CC.COc1ccc2c(c1)C(=O)C(C)CC2>>CCC1CCc2ccc(OC)cc2C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100204240A1,CC1(C)O[C@@H](C(Cl)=NO)C(C)(C)O1.CS(=O)(=O)Cl>>CC1(C)O[C@@H](C(Cl)=NOS(C)(=O)=O)C(C)(C)O1,,CCOCC,,CCN(CC)CC,,test
US20030069271A1,BrCCC1CCC1.CCCc1c(O)c2c([N+](=O)[O-])c(F)ccc2[nH]c1=O>>CCCc1c(OCC2CCC2)c2c([N+](=O)[O-])c(F)ccc2[nH]c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20140163001A1,CCOC(=O)c1c[nH]nc1-c1ccc(F)cc1>>O=C(O)c1c[nH]nc1-c1ccc(F)cc1,,CCO,,[Na+].[OH-],,test
US04544659,COc1c2ccccc2nc2ccccc12.NNC1=NCCS1>>c1ccc2c(=NN=C3NCCS3)c3ccccc3[nH]c2c1,,CCO,,Br,,test
US20150166549A1,CC(c1oc(=O)c2ccccc2c1-c1ccccc1)n1nc(I)c2c(N)ncnc21.OB(O)c1cnc(C(F)(F)F)c(OCc2ccccc2)c1>>CC(c1oc(=O)c2ccccc2c1-c1ccccc1)n1nc(-c2cnc(C(F)(F)F)c(O)c2)c2c(N)ncnc21,[Pd],CC(C)O,,Cl,[H][H],test
US20070066618A1,CCc1nc2cc(C(F)(F)F)c(Cl)cc2n1-c1ccc(CCOC(=O)Oc2ccccc2)cc1.NS(=O)(=O)c1cccnc1>>CCc1nc2cc(C(F)(F)F)c(Cl)cc2n1-c1ccc(CCOC(=O)NS(=O)(=O)c2cccnc2)cc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20090197871A1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2cccc(-c3cccc(CN4CCN(C(=O)OC(C)(C)C)[C@@H](C)C4)c3)c2F)c1>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2cccc(-c3cccc(CN4CCN[C@@H](C)C4)c3)c2F)c1,,C1CCOC1,,O=C(O)C(F)(F)F,,test
US20060046985A1,CC(C)(C)OC(=O)NOCc1ccccc1.CC(Cl)CCC#N>>CC(C)(C)OC(=O)N(CCCCC#N)OCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20150080393A1,Cc1cc(Br)ccc1CO>>Cc1cc(Br)ccc1C=O,,ClCCl,O,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20090286778A1,CC(C)(C)NC(=O)N1CCN(c2ccc3cc2CCc2cccc(c2)Nc2ncc(Cl)c(n2)N3)CC1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F>>NC(=O)N1CCN(c2ccc3cc2CCc2cccc(c2)Nc2ncc(Cl)c(n2)N3)CC1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,,O=C(O)C(F)(F)F,,,,test
US20120208798A1,CC(=O)N1c2ccc(-c3ccc(CN4CCN(C(=O)OC(C)(C)C)CC4=O)cc3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C.Cl>>CC(=O)N1c2ccc(-c3ccc(CN4CCNCC4=O)cc3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C.Cl,,C1COCCO1,,,,test
US20110224202A1,CCOC(C)OC(c1noc(-c2cc(OC)c(Br)c(OC)c2)n1)C(OC)c1ccc(N2CCOCC2)cc1>>COc1cc(-c2nc(C(O)C(OC)c3ccc(N4CCOCC4)cc3)no2)cc(OC)c1Br,,CO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20140221345A1,CCOC(=O)CBr.NC(=O)c1cccc(O)c1>>CCOC(=O)COc1cccc(C(N)=O)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070208007A1,CCCN(C(=O)CCCCCNC(=O)OCc1ccccc1)c1cc(C#N)ccc1N>>CCCn1c(CCCCCNC(=O)OCc2ccccc2)nc2ccc(C#N)cc21,,CO,,C1COCCO1,Cl,test
US20110136780A1,C1CCNC1.CC[C@@H](NC(=O)OC(C)(C)C)C(=O)O>>CC[C@@H](NC(=O)OC(C)(C)C)C(=O)N1CCCC1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04317920,Cc1ccccc1S(=O)(=O)Oc1c(Oc2ccccc2)cccc1C(C)C(=O)O>>CC(C(=O)O)c1cccc(Oc2ccccc2)c1,[Ni],,,[H][H],,test
US20090088459A1,CC(C)CBr.CS(=O)(=O)c1cccc(-c2ccc(CNS(=O)(=O)c3cccc(Cl)c3)s2)c1>>CC(C)CN(Cc1ccc(-c2cccc(S(C)(=O)=O)c2)s1)S(=O)(=O)c1cccc(Cl)c1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20140275032A1,O=S(=O)(n1ccnc1)n1ccnc1.Oc1ccccc1>>O=S(=O)(Oc1ccccc1)n1ccnc1,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100222347A1,C1CCOC1.CC(=O)N1c2ccc(C(=O)NN)cc2C(Nc2ccc(Cl)cc2)CC1C.O>>CC(=O)N1c2ccc(-c3n[nH]c(=O)o3)cc2C(Nc2ccc(Cl)cc2)CC1C,,O,,CCN(CC)CC,,test
US04205074,CI.c1csc(C(=C2CC3CCCCN3C2)c2cccs2)c1>>CI.c1csc(C(=C2CC3CCCCN3C2)c2cccs2)c1,,CC(C)=O,,,,test
US20130224186A1,CCOC(=O)c1nc(-c2cc(F)ccc2F)oc1Cc1ccccc1>>OCc1nc(-c2cc(F)ccc2F)oc1Cc1ccccc1,,C1CCOC1,,[BH4-].[Li+],,test
US20160002248A1,CC(C)(C)OC(=O)c1cn(CCCCc2cc(C#CC3CN(C(=O)OC(C)(C)C)C3)c(N)nn2)nn1>>CC(C)(C)OC(=O)N1CC(c2cc3cc(CCCCn4cc(C(=O)O)nn4)nnc3[nH]2)C1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20080188657A1,CC(C)c1cc(-c2ccc(F)cc2)nc(O)n1.O=C1CCC(=O)N1Br>>CC(C)c1nc(O)nc(-c2ccc(F)cc2)c1Br,,O,,CN(C)C=O,,test
US20060004052A1,CC(C)(C)OC(=O)N[C@@H](C(=O)Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O)c1ccc(O)cc1.Cl>>Cl.N[C@@H](C(=O)Nc1cc2c3c(c(-c4ccccc4)[nH]c3c1)C=NNC2=O)c1ccc(O)cc1,,C1COCCO1,,CCN(CC)CC,,test
US05025008,COC(=O)c1ccc2c(c1)oc1cc(Br)ccc12>>O=C(O)c1ccc2c(c1)oc1cc(Br)ccc12,,CO,,C1CCOC1,[Na+].[OH-],test
US05571818,CCOC(=O)c1cc2cccc(O)c2cc1O.N#CC(=Cc1cccc([N+](=O)[O-])c1)C(O)C#N>>CCOC(=O)c1cc2ccc3c(c2cc1O)OC(N)=C(C#N)C3c1cccc([N+](=O)[O-])c1,,CCO,CCOCC,C1CCNCC1,,test
US20090099155A1,CC(C)(C)OC(=O)c1ccc(CCC2CCCCC2)nc1CN.NCc1ccc(CCC2CCCCC2)nc1>>N#Cc1ccc(C#CC2CCCCC2)nc1,,CO,,O=C(O)C(F)(F)F,,test
US20120264749A1,CC(C)(CO)NCc1ccccc1>>CC(C)(CO)NCc1ccccc1,,CCOCC,,Cl,[Na+].[OH-],test
US05135938,BrCCCCCCSc1ccccc1.O=C(O)c1ccccc1S>>O=C(O)c1ccccc1SCCCCCCSc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160157491A1,CN1N=C2c3ccc(Br)cc3CCC2C1c1ccc(OC(F)(F)F)cc1>>Cn1nc2c(ccc3cc(Br)ccc32)c1-c1ccc(OC(F)(F)F)cc1,,C1COCCO1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US04526720,C#C[C@]1(O)C(=C)C[C@H]2[C@@H]3C[C@@H](CN(CC)c4ccccc4)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C>>C#C[C@]1(O)C(=C)C[C@H]2[C@@H]3CC(=C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C,,C1CCOC1,,Cl,O,test
US20100233116A1,ClCc1ccncn1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1Cc1ccncn1,,CN(C)C=O,,[K],,test
US20100216794A1,O=[N+]([O-])c1ncc(Cl)cc1OC1CCCC1.Oc1ccccc1>>O=[N+]([O-])c1ncc(Oc2ccccc2)cc1OC1CCCC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130345123A1,COC(=O)[C@H]1CCCCN1C(=O)[C@H](CNC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1.O=C(O)C(F)(F)F>>COC(=O)[C@H]1CCCCN1C(=O)[C@H](CN)NC(=O)OCc1ccccc1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20080255144A1,CC(C)(C)OC(=O)N1CCN(c2ccc(C=O)cc2Cl)CC1>>O=Cc1ccc(N2CCNCC2)c(Cl)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100105679A1,FC(F)(F)c1ccc(CBr)cc1.O=c1cc(O)ccn1-c1ccc2c(cnn2CCN2CCCC2)c1>>O=c1cc(OCc2ccc(C(F)(F)F)cc2)ccn1-c1ccc2c(cnn2CCN2CCCC2)c1,,C1CCOC1,,[H-].[Na+],,test
US20050209274A1,CC[Zn]CC.O=C(O)c1cc(=O)c2cc(F)c(Br)cc2o1>>CCc1cc2oc(C(=O)O)cc(=O)c2cc1F,,c1ccccc1,,CCCCCCC,,test
US20090318501A1,CC(C)(C)OC(=O)N1[C@@H](C[C@H]2CCCOC2)COC1(C)C>>CC(C)(C)OC(=O)N[C@H](CO)C[C@H]1CCCOC1,,CC(=O)O,,,,test
US20160016948A1,C#Cc1cn(C(C)C)c2cc(Br)ncc12.[N-]=[N+]=NCc1ccccc1>>CC(C)n1cc(-c2cnn(Cc3ccccc3)n2)c2cnc(Br)cc21,[Cu]I,O,,CN(C)C=O,,test
US20110212946A1,Cl.N#CC(=C1CCOCC1)c1ccccc1>>[Cl-].[NH3+]CC(c1ccccc1)C1CCOCC1,[Pd],CCO,,,,test
US20090023708A1,CC1CCCN1CCCOc1ccc(I)cc1.O=C1CC[C@@H](CN2CCCCC2)N1>>CC1CCCN1CCCOc1ccc(N2C(=O)CC[C@H]2CN2CCCCC2)cc1,I[Cu]I,C1COCCO1,ClCCl,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20090036492A1,BrP(Br)Br.CN(C)C=O.Cc1cc(F)c2c(c1)C(=O)CCC2>>Cc1cc(F)c2c(c1)C(Br)=C(C=O)CC2,,ClC(Cl)Cl,,,,test
US20060003968A1,CC(C)[Si](C(C)C)(C(C)C)n1ccc2cc(F)cnc21>>Fc1cnc2[nH]ccc2c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04904690,Cc1cccc(C(=O)CC(=O)C2CCCC2)c1O>>Cc1cccc2c(=O)cc(C3CCCC3)oc12,,CC(=O)O,,O,O=S(=O)(O)O,test
US04020058,CC(C)(C)OC(=O)C1(Br)CCCC1.O=C(O)C(=NO)c1ccco1>>CC(C)(C)OC(=O)C1(ON=C(C(=O)O)c2ccco2)CCCC1,,O,,,,test
US20070213333A1,Brc1ccc(Br)nc1.OCC1CCCC1>>Brc1ccc(OCC2CCCC2)nc1,,C1CCOC1,CCOC(C)=O,O,CC(C)(C)[O-].[K+],test
US20080287489A1,COc1ccc2sc(C(=O)C(C)(C)C)c(CC(O)C(C)(C)C)c2c1>>COc1ccc2sc(C(=O)C(C)(C)C)c(CC(=O)C(C)(C)C)c2c1,,CC#N,,,,test
US20120225854A1,CC#C[Mg]Br.CC(C)(C)OC(=O)N1CCN(C(=O)OCc2ccccc2)CC1=O>>CC#CC(=O)CN(CCNC(=O)OC(C)(C)C)C(=O)OCc1ccccc1,,C1CCOC1,,[Cl-].[NH4+],,test
US20070219186A1,CNC.CO.O=Cc1cc(C=O)cc(-c2cnn3c(-c4cccc(NC(=O)c5cccc(C(F)(F)F)c5)c4)ccnc23)c1.[BH3-]C#N>>CN(C)Cc1cc(CN(C)C)cc(-c2cnn3c(-c4cccc(NC(=O)c5cccc(C(F)(F)F)c5)c4)ccnc23)c1,,CO,,CC(=O)O,,test
US20070105943A1,NCC1CC1.O=C(NCc1ccc(Oc2ccccc2)s1)c1cccnc1Cl>>O=C(NCc1ccc(Oc2ccccc2)s1)c1cccnc1NCC1CC1,,CS(C)=O,,O=C(O)C(F)(F)F,,test
US20160214972A1,CC(C)(C)OC(=O)COCCCOCCOCc1ccccc1>>CC(C)(C)OC(=O)COCCCOCCO,[Pd],CO,,[H][H],,test
US20110172187A1,Nc1ccc2c(c1)B(O)OC2.O=S(=O)(Cl)c1ccc2[nH]ncc2c1>>O=S(=O)(Nc1ccc2c(c1)B(O)OC2)c1ccc2[nH]ncc2c1,,c1ccncc1,,O,,test
US06762189B1,CCOC(=O)c1cnc(SC)nc1Cl.Nc1ccc2[nH]ncc2c1>>CCOC(=O)c1cnc(SC)nc1Nc1ccc2[nH]ncc2c1,,CO,,CCN(CC)CC,,test
US20150329653A1,CC(C)(C)c1cc([Mg]Br)cc(C(C)(C)C)c1.COC1c2cc(C)cc(Cl)c2CC1C>>COC1c2cc(C)cc(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)c2CC1C,,C1CCOC1,,O,,test
US20060258687A1,Cc1ccc(C(=O)Nc2ccc(F)cc2)cc1B1OC(C)(C)C(C)(C)O1.O=C1NCc2c(Cl)nc(N3CCC(N4CCCC4)CC3)nc2N1c1c(F)cccc1F>>Cc1ccc(C(=O)Nc2ccc(F)cc2)cc1-c1nc(N2CCC(N3CCCC3)CC2)nc2c1CNC(=O)N2c1c(F)cccc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US20100197634A1,Cc1ccc(CN)cc1Nc1nc2ccc(F)cc2c2c(=O)[nH]ccc12.O=S(=O)(Cl)C(F)(F)F>>Cc1ccc(CNS(=O)(=O)C(F)(F)F)cc1Nc1nc2ccc(F)cc2c2c(=O)[nH]ccc12,,C1CCOC1,,CCN(CC)CC,,test
US20150148347A1,CCOC(=O)[C@H]1C[C@@H]1c1ccc(O[C@@H]2CCc3c(O)ccc(F)c32)cc1.N#Cc1ccc(F)cc1>>CCOC(=O)[C@H]1C[C@@H]1c1ccc(O[C@@H]2CCc3c(Oc4ccc(C#N)cc4)ccc(F)c32)cc1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040010141A1,BrCCCBr.CCOC(=O)C(Nc1ccc(Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)nc1)C(=O)OCC>>CCOC(=O)C1(C(=O)OCC)CCCN1c1ccc(Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)nc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100174065A1,CC(C)Oc1ncc(-c2nc(-c3cccc4c3OCCN(C(=O)OC(C)(C)C)C4)no2)cc1Cl.Cl>>CC(C)Oc1ncc(-c2nc(-c3cccc4c3OCCNC4)no2)cc1Cl.Cl,,C1COCCO1,,,,test
US20070253957A1,CCC(=O)c1ccc(Nc2c3cccc([N+](=O)[O-])c3nc3c2c(C)nn3C)cc1>>CCC(=O)c1ccc(Nc2c3cccc(N)c3nc3c2c(C)nn3C)cc1,,CO,,,,test
US20040092582A1,CC(=O)OC(C)=O.CN(C)Cc1c(O)c2c(c3c1CC(C)(C)N=C3c1ccccc1)CC(C)(C)O2>>CC(=O)Oc1c(CN(C)C)c2c(c3c1OC(C)(C)C3)C(c1ccccc1)=NC(C)(C)C2,,c1ccncc1,,O,,test
US04092311,CNN.Clc1ccc(-c2ccccc2)nn1>>CN(N)c1ccc(-c2ccccc2)nn1,,CCCCO,,,,test
US06239131B1,Cc1ccc2c(c1)NC(=O)C(NC(=O)OC(C)(C)C)CN2.O=C(Cl)c1ccco1>>Cc1ccc2c(c1)NC(=O)C(NC(=O)OC(C)(C)C)CN2C(=O)c1ccco1,,ClCCCl,,O,c1ccncc1,test
US05229388,CC1SC(C)(C)C(=O)N1CCCCCl.O=S(=O)([O-])O[O-]>>CC1N(CCCCCl)C(=O)C(C)(C)S1(=O)=O,,CCO,,O,,test
US20120220571A1,BrCc1ccccc1.C=CCCn1c2c(c(=O)c(O)c1C(C)C=C)C(=O)N(Cc1ccc(F)cc1)CC2>>C=CCCn1c2c(c(=O)c(OCc3ccccc3)c1C(C)C=C)C(=O)N(Cc1ccc(F)cc1)CC2,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090286882A1,CCOC(=O)CC1(CCC(CO)Cc2ccc(C(=O)OC)cc2)CC1>>CCOC(=O)CC1(CCC(C=O)Cc2ccc(C(=O)OC)cc2)CC1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US05206240,O=C(c1ccccc1)N1CCC2(CC1)Cc1ccccc1C2=O>>O=C1c2ccccc2CC12CCNCC2,,CCO,Cl,,,test
US20020161036A1,C#CCOc1ccc2c(C)cc(=O)oc2c1C(C)=O.O=Cc1ccccc1>>C#CCOc1ccc2c(C)cc(=O)oc2c1C(=O)C=Cc1ccccc1,,CCO,O,[K+].[OH-],,test
US20110245257A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)O.NC1=CC=CN(c2cc(F)cc(F)c2)C1N>>C[C@H](NC(=O)OC(C)(C)C)C(=O)Nc1cccnc1Nc1cc(F)cc(F)c1,,ClCCl,O,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20080275037A1,Cc1ccc(N2CCc3ncnc(Cl)c3C2)c(C#N)c1.NCc1ccc2ocnc2c1>>Cc1ccc(N2CCc3ncnc(NCc4ccc5ocnc5c4)c3C2)c(C#N)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US06486155B1,COC(=O)c1c(-c2cc(OC)c(OC)c(OC)c2)c2ccc(O)cc2c(=O)n1-c1ccc(N)cc1>>COC(=O)c1c(-c2cc(OC)c(OC)c(OC)c2)c2ccc(O)cc2c(=O)n1-c1ccc(N)cc1,,ClC(Cl)Cl,,Cl,[Na+].[OH-],test
US20090253699A1,COC(=O)c1cccc(-c2nnc(-c3ccc(-c4cccc(C)c4)cc3)o2)c1>>Cc1cccc(-c2ccc(-c3nnc(-c4cccc(C(=O)O)c4)o3)cc2)c1,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20070218483A1,Cc1ccc(C(=O)c2c(F)cccc2F)cc1.O=C1CCC(=O)N1Br>>O=C(c1ccc(CBr)cc1)c1c(F)cccc1F,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20150225397A1,CC(=O)Cl.C[C@@H]1C(=O)C(C#N)=C[C@]2(c3ccccc3)c3n[nH]cc3CCC12>>CC(=O)n1cc2c(n1)[C@@]1(c3ccccc3)C=C(C#N)C(=O)[C@@H](C)[C@@H]1CC2,,C1CCOC1,,CCN(CC)CC,,test
US20070173501A1,CC(C)(C)OC(=O)n1cccc1C1=C/C(=C2\C(=O)Nc3cc(F)ccc32)OC1>>O=C1Nc2cc(F)ccc2/C1=C1/C=C(c2ccc[nH]2)CO1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20070082880A1,N#Cc1cnc2sc(-c3ccccc3)cc2c1Cl.Nc1ccc2[nH]ccc2c1>>N#Cc1cnc2sc(-c3ccccc3)cc2c1Nc1ccc2[nH]ccc2c1,,CCOCCO,,Cl,c1ccncc1,test
US20060058246A1,NCCNCCO.O=Cc1nccs1>>OCCNCCNCc1nccs1,,CCO,,,,test
US20120172351A1,COC(=O)C[C@@H]1COc2cc(N)ccc21.Cc1ccc(C=O)c(C)c1C1=CCC2(CC1)OCCO2>>COC(=O)C[C@@H]1COc2cc(NCc3ccc(C)c(C4=CCC5(CC4)OCCO5)c3C)ccc21,,CC#N,,CC(=O)O,O=C([O-])O.[Na+],test
US06800778B1,CCOC(=O)C(C)(C)C(=O)c1ccccc1Cl>>CCOC(=O)C(C)(C)C(O)c1ccccc1Cl,,O,,CO,,test
US07569601B2,C=CC(=O)OC(C)(C)C.Oc1ccc(C(=C2CCCCC2)c2ccc(Br)cc2F)cc1>>CC(C)(C)OC(=O)/C=C/c1ccc(C(=C2CCCCC2)c2ccc(O)cc2)c(F)c1,,O,,CCN(CC)CC,Cc1ccccc1P(c1ccccc1C)c1ccccc1C,test
US20050009845A1,Brc1nccs1.C#Cc1cc2c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)ncnc2s1>>Fc1cccc(COc2ccc(Nc3ncnc4sc(C#Cc5nccs5)cc34)cc2Cl)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,,CCN(CC)CC,,test
US20120295884A1,CC(=O)c1nn(CC(=O)OC(C)(C)C)c2cnc(C)cc12>>CC(=O)c1nn(CC(=O)O)c2cnc(C)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100256097A1,CC(C)(C)[Si](C)(C)O[C@@H]1CC(=O)N(Cc2cccc(Br)n2)C1>>O=C1C[C@@H](O)CN1Cc1cccc(Br)n1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100063104A1,C=C(CO)C(=O)O.CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.c1c[nH]cn1>>C=C(CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)C(=O)OCC,,CN(C)C=O,,Cl,,test
US20160009644A1,BrCCSC(c1ccccc1)c1ccccc1.c1ccc(CCCN2CCNCC2)cc1>>c1ccc(CCCN2CCN(CCSC(c3ccccc3)c3ccccc3)CC2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030109750A1,CS(=O)(=O)c1ccccc1[N+](=O)[O-]>>CS(=O)(=O)c1ccccc1N,[Pd],CCO,,,,test
US04645765,CCC(=O)Cl.CN(C)C=O.CN(C)c1ccncc1.NC(=O)OCC1c2c(O)cc(C=O)cc2N2CC3NC3C1(O)O2>>CCC(=O)Oc1cc(C=O)cc2c1C(COC(N)=O)C1(O)ON2CC2C1N2C(=O)CC,CN(C)c1ccncc1,CN(C)C=O,,,,test
US20040147543A1,CSCCCNc1c([N+](=O)[O-])cnc2cc(-c3ccccc3)ccc12>>CSCCCNc1c(N)cnc2cc(-c3ccccc3)ccc12,[Pt],Cc1ccccc1,,,,test
US07235572B2,Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CCl.Oc1cccc2[nH]ccc12>>Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1cccc2[nH]ccc12,,CC(C)=O,,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US05539112,COCN(C(=O)OC(C)(C)C)c1ccc(-c2cc(=O)c3c(NCCC=C(C)C)c(F)cc(F)c3o2)cc1F>>CC(C)=CCCNc1c(F)cc(F)c2oc(-c3ccc(N)c(F)c3)cc(=O)c12,,CCO,,O,O=S(=O)(O)O,test
US20130336921A1,O=C(Nc1ccc(N2CCCCC2)cc1C(=O)Nc1ccn(-c2cccc(C(F)(F)F)c2)n1)c1cccc(CCl)c1.O=C(O)c1ccc(S)cc1>>O=C(O)c1ccc(SCc2cccc(C(=O)Nc3ccc(N4CCCCC4)cc3C(=O)Nc3ccn(-c4cccc(C(F)(F)F)c4)n3)c2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080275103A1,CC(C)c1cc(-c2ccccc2)c(CCCO)n1C(=O)OC(C)(C)C>>CC(C)c1cc(-c2ccccc2)c(CCCO)[nH]1,,CO,,C[O-].[Na+],,test
US20040072863A1,COC(=O)C(O)(c1cccs1)C1CCCCC1.O[C@H]1CN2CCC1CC2>>O=C(O[C@H]1CN2CCC1CC2)C(O)(c1cccs1)C1CCCCC1,,Cc1ccccc1,,,,test
US20040009995A1,CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2c(C)cc(NC(=O)OCC[Si](C)(C)C)cc2NC(=O)NCCCCCC(=O)O)c1>>CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2c(C)cc(N)cc2NC(=O)NCCCCCC(=O)O)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20060025601A1,C=CCBr.CCC1c2cc(I)c(O)cc2C2CNCC12.CCNC(=O)[O-]>>C=CCOc1cc2c(cc1I)C(C)C1CNCC21.CCNC(=O)[O-],,ClCCl,O,C1CCC2=NCCCN2CC1,,test
US20080113923A1,CC(C)CCCC(C)CCCC(C)CCCC(C)CCCC(=O)OC[C@H](O)[C@H](O)CO.O>>CC(C)CCCC(C)CCCC(C)CCCC(C)CCCC(=O)OC[C@H](O)[C@H](O)CO.O,,O,,,,test
US20080181866A1,CC(C)(C)OC(=O)NCc1ccc(NC(=O)C2CSC(c3ccncc3)N2C(=O)OCc2ccccc2)cc1>>NCc1ccc(NC(=O)C2CSC(c3ccncc3)N2C(=O)OCc2ccccc2)cc1,,ClCCl,,CCOCC,Cl,test
US20090181942A1,COc1cccc([C@H]2O[C@H](CC3OCCO3)c3nccn3-c3ccc(Cl)cc32)c1OC>>COc1cccc([C@H]2O[C@H](CCO)c3nccn3-c3ccc(Cl)cc32)c1OC,,ClCCl,,[O-][Cl+3]([O-])([O-])O,,test
US20050143588A1,CC(=O)OC(C)=O.COc1cccc(-c2coc3cc(O)ccc3c2=O)c1>>COc1cccc(-c2coc3cc(OC(C)=O)ccc3c2=O)c1,,c1ccncc1,,,,test
US20130289058A1,OCC12CCC(c3ccc(Cl)cc3)(OC1)C(Br)C2>>O=CC12CCC(c3ccc(Cl)cc3)(OC1)C(Br)C2,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20130331419A1,CCC(c1ccc(Cl)cc1)(c1nc(C(N)=O)no1)n1ncc2c(NS(C)(=O)=O)cccc21>>CCC(c1ccc(Cl)cc1)(c1nc(C#N)no1)n1ncc2c(NS(C)(=O)=O)cccc21,,c1ccncc1,,O=P(Cl)(Cl)Cl,,test
US20140045823A1,CCOC(=O)c1ncc(-c2ccc(S(C)(=O)=O)cc2)o1>>CS(=O)(=O)c1ccc(-c2cnc(C(=O)O)o2)cc1,,C1CCOC1,,[Na+].[OH-],,test
US20080146547A1,CC(C)OC(=O)NCc1cccc(NCCN2CCOCC2)c1.Cl>>Cl.NCc1cccc(NCCN2CCOCC2)c1,,CO,,,,test
US20140142122A1,BrC(Br)(Br)Br.OCCOC1CCCCC1>>BrCCOC1CCCCC1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20040034034A1,CCOC(=O)C(C)S(=O)(=O)Cl.C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](C)CN1C(=O)COc1ccc(Cl)cc1CN>>CC(C(=O)O)S(=O)(=O)NCc1cc(Cl)ccc1OCC(=O)N1C[C@H](C)N(Cc2ccc(F)cc2)C[C@H]1C,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,CN(C)c1ccccn1,test
US20080318944A1,C=O.CON(C)C(=O)C1CNCCN1C(=O)OCc1ccccc1>>CON(C)C(=O)C1CN(C)CCN1C(=O)OCc1ccccc1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20160243100A1,CC(C)(C)OC(=O)N1CCC(C(F)(F)S(=O)(=O)c2cccnc2Cl)CC1.N>>CC(C)(C)OC(=O)N1CCC(C(F)(F)S(=O)(=O)c2cccnc2N)CC1,,CCO,,,,test
US06329370B1,C1CCNC1.COc1ccc2c(Cc3ccco3)nnc(Cl)c2c1>>COc1ccc2c(Cc3ccco3)nnc(N3CCCC3)c2c1,,CCOC(C)=O,CN(C)C=O,,,test
US20050153971A1,CS(=O)(=O)Cl.O=C1OC(CO)CN1c1cccc(F)c1>>CS(=O)(=O)OC[C@H]1CN(c2cccc(F)c2)C(=O)O1,,ClCCl,,,,test
US20110190280A1,Br.O=C(OCc1ccccc1)N1CCC(Oc2ccc([N+](=O)[O-])cc2F)CC1>>Br.O=[N+]([O-])c1ccc(OC2CCNCC2)c(F)c1,,CCOCC,,,,test
US20160002205A1,CCOc1cccnc1N1CCN(C)CC1.O=C1CCC(=O)N1Br>>COc1cc(Br)cnc1N1CCN(C)CC1,,CC#N,,,,test
US20110086858A1,C=CCOc1ccc(CN)cc1.COC(=O)c1ccc(Nc2nc(Cl)nc(OCC(F)(F)F)n2)cc1>>C=CCOc1ccc(CNc2nc(Nc3ccc(C(=O)OC)cc3)nc(OCC(F)(F)F)n2)cc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20140363371A1,C[C@H](CCC(=O)OC(C)(C)C)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](OCC(O)CN)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C.O=C(OCC1c2ccccc2-c2ccccc21)ON1C(=O)CCC1=O>>C[C@H](CCC(=O)OC(C)(C)C)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](OCC(O)CNC(=O)OCC5c6ccccc6-c6ccccc65)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C,,CCCCCC,CCOC(C)=O,CCN(C(C)C)C(C)C,ClCCl,test
US04959361,C#CCN1C(=O)CCc2ccccc21.Cc1nnc2n1-c1ccc(I)cc1C(c1ccccc1F)=N[C@H]2C>>Cc1nnc2n1-c1ccc(C#CCN3C(=O)CCc4ccccc43)cc1C(c1ccccc1F)=N[C@H]2C,,ClCCl,,CCO,,test
US20080207902A1,CSc1cc2c(COC3CCCCO3)ccc(I)n2n1>>CSc1cc2c(C=O)ccc(I)n2n1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20130005744A1,CI.O=c1[nH]c(I)ccc1OCc1ccccc1>>Cn1c(I)ccc(OCc2ccccc2)c1=O,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20040048908A1,CCOP(=O)(Cc1ccc(NC(=O)CCc2cnoc2-c2ccccc2)cc1)OCC>>CCOP(=O)(O)Cc1ccc(NC(=O)CCc2cnoc2-c2ccccc2)cc1,,CC#N,,C[Si](C)(C)Br,,test
US20140242028A1,COc1ccc(S)cc1.O=[N+]([O-])c1cc(Cl)c(F)c(Cl)c1>>COc1ccc(Sc2c(Cl)cc([N+](=O)[O-])cc2Cl)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05164407,CCCc1nc2c(c(C)nn2C)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCc1nc2c(c(C)nn2C)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,CC(=O)O,,O,,test
US20060264425A1,C[Si](C)(C)C(F)(F)F.Cn1cc2ccc(NC(=O)c3ccccc3NCc3ccnc(NC(=O)N4CCC(=O)CC4)c3)cc2n1>>Cn1cc2ccc(NC(=O)c3ccccc3NCc3ccnc(NC(=O)N4CCC(O)(C(F)(F)F)CC4)c3)cc2n1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040010009A1,Cc1cc(OC2CCN(C(=O)OC(C)(C)C)CC2)c(C(N)=O)cc1[N+](=O)[O-]>>Cc1cc(OC2CCN(C(=O)OC(C)(C)C)CC2)c(C(N)=O)cc1N,[Pd],CO,,,,test
US04075001,CCN(CC)C(N)=C(C#N)C#N.S>>CCN(CC)C(N)=C(C#N)C(N)=S,,CN(C)C=O,,CCN(CC)CC,c1ccncc1,test
US20090239845A1,Cc1cc(-c2nc3cc(CO)ccc3[nH]2)nn1Cc1cc(Cl)ccc1OCc1ccccc1>>Cc1cc(-c2nc3cc(C=O)ccc3[nH]2)nn1Cc1cc(Cl)ccc1OCc1ccccc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20070082931A1,Cc1ccc(S(=O)(=O)OCC2CCOCC2)cc1.O=C(O)c1c[nH]c2c(Cl)cccc12>>O=C(O)c1cn(CC2CCOCC2)c2c(Cl)cccc12,,CN(C)C=O,,[H-].[Na+],,test
US20110065708A1,CC(=O)c1ccc2nnc(Cc3c(F)cc4ncccc4c3F)n2n1.NO>>C/C(=N\O)c1ccc2nnc(Cc3c(F)cc4ncccc4c3F)n2n1,,CO,,Cl,[Na+].[OH-],test
US06982263B2,CC(C)CC(O)C(=O)NC(COCc1ccccc1)C(N)=O.O=C(Cl)N1CCOCC1>>CC(C)CC(OC(=O)N1CCOCC1)C(=O)NC(C#N)COCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20090030020A1,C#Cc1ccccc1C.COC(=O)c1nc(SC)ncc1Br>>COC(=O)c1nc(SC)ncc1C#Cc1ccccc1C,[Cu]I,CN(C)C=O,ClCCl,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020045777A1,CCNCCO.CN(C(=O)Oc1ccc(Cl)cc1)[C@@H]1CC[C@@H](CSCCCl)CC1>>CCN(CCO)CCSC[C@@H]1CC[C@@H](N(C)C(=O)Oc2ccc(Cl)cc2)CC1,,CC(=O)N(C)C,,[I-].[Na+],,test
US04033962,C=C(C#N)C(OC)OC.COc1ccc(C)cc1OC>>COC=C(C#N)Cc1cc(OC)c(OC)cc1C,,ClCCl,,,,test
US20130150339A1,O=P(Cl)(Cl)Cl.O=c1[nH]cnc2cc(SCc3ccccc3)ccc12>>Clc1ncnc2cc(SCc3ccccc3)ccc12,,ClCCCl,,CCN(C(C)C)C(C)C,,test
US05753664,O=C(c1ccc(F)cc1)c1ccc(CBr)cc1.O=c1[nH]c(S)nc2[nH]ccc12>>O=C(c1ccc(F)cc1)c1ccc(CSc2nc3[nH]ccc3c(=O)[nH]2)cc1,,CO,COCCOC,[Na+].[OH-],,test
US20100137353A1,OC/C=C/c1cc(F)ccc1F>>O=C/C=C/c1cc(F)ccc1F,O=[Mn]=O,,,,,test
US20060058320A1,NC(=S)NCCN1CCOCC1.Nc1nc(C(=O)CBr)cc2nc(-c3ccco3)nn12>>Nc1nc(-c2csc(NCCN3CCOCC3)n2)cc2nc(-c3ccco3)nn12,,CCO,,,,test
US20120053166A1,C[C@H]1CN(CC(=O)NN)C[C@@H](C)O1.Cn1ncc2c(C(=O)O)cc(Br)cc21>>C[C@H]1CN(CC(=O)NNC(=O)c2cc(Br)cc3c2cnn3C)C[C@@H](C)O1,,C1CCOC1,,CCN(C(C)C)C(C)C,O=S(Cl)Cl,test
US06403804B1,COC(=O)C[C@H](O)c1ccccc1.NN>>NNC(=O)C[C@H](O)c1ccccc1,,CO,,O,,test
US04945100,CCCC(CO)(OCC)c1ccc(Cl)cc1Cl.CS(=O)(=O)[O-]>>CCCC(COS(C)(=O)=O)(OCC)c1ccc(Cl)cc1Cl,,c1ccncc1,,,,test
US20140031364A1,Fc1ccccc1N1CCNCC1.Nc1onc(-c2ccccc2Cl)c1C(=O)O>>Nc1onc(-c2ccccc2Cl)c1C(=O)N1CCN(c2ccccc2F)CC1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20090291940A1,CC(=O)O[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N1C[C@@H](O)[C@H](NC(=O)OCc2ccccc2)C1,,CO,,O,O=C([O-])[O-].[K+].[K+],test
US20050256158A1,CCOC(=O)c1nccn1CCCOc1ccc(C(=O)N2c3ccccc3[C@H](N(C(C)=O)c3ccc(Cl)cc3)C[C@@H]2C)cc1>>CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(OCCCn3ccnc3C(=O)O)cc2)c2ccccc21,,C1CCOC1,,CCO,[Na+].[OH-],test
US04272437,O=C(Cl)C(=O)Cl.[N-]=[N+]=NC[C@@H]1C[C@H]1C(=O)O>>[N-]=[N+]=NC[C@@H]1C[C@H]1C(=O)Cl,,ClCCl,,CN(C)C=O,,test
US20080194549A1,CC(C)COC(=O)Cl.CCc1ccc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CNC2CC2)C(C)C)cc1OCCCOC>>CCc1ccc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN(C(=O)OCC(C)C)C2CC2)C(C)C)cc1OCCCOC,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US05407451,CC(O)CO.CCCCCCCCSCCCCCCCC.OB(O)O>>CC(O)CO.CCCCCCCCSCCCCCCCC.OB(O)O,,Cc1ccccc1,,CCCCO,,test
US20070219234A1,C/C(=C(\C#N)C(N)=S)N1CCC(c2ccccc2)CC1.COC(OC)N(C)C>>C/C(=C(\C#N)C(=S)/N=C/N(C)C)N1CCC(c2ccccc2)CC1,,CCO,,,,test
US20100016319A1,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2O)cc1.O=[N+]([O-])c1cnc(Cl)nc1Cl>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2ccccc2Oc2nc(Cl)ncc2[N+](=O)[O-])cc1,,CC(C)=O,O,O=C(O)CC(O)(CC(=O)O)C(=O)O,[Na+].[OH-],test
US20080194812A1,CC(C)(C)C(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@]4(C)C(=O)[C@H]5C[C@H]5[C@H]4[C@@H]3C=C[C@]2(O)C1>>C[C@]12CC[C@H]3[C@@H](C=C[C@]4(O)C[C@@H](O)CC[C@]34C)[C@@H]1[C@@H]1C[C@@H]1C2=O,[Zn],C1CCOC1,CC(=O)O,[K+].[OH-],,test
US20140275523A1,CC(N)=NNC(C)C.O=C(O)c1c[nH]c(-c2ccc(Br)cc2F)n1>>CC(=NC(=O)c1c[nH]c(-c2ccc(Br)cc2F)n1)NNC(C)C,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20130116431A1,COCOc1cc(OCOC)c(C(C)C)cc1-c1nnc(S(C)(=O)=O)n1-c1ccc(OC)cc1>>COc1ccc(-n2c(-c3cc(C(C)C)c(O)cc3O)n[nH]c2=O)cc1,,CS(C)=O,,[Na+].[OH-],[Cl-].[NH4+],test
US20100010024A1,CC(=O)CC(=O)C(C)C.N#Cc1ccc(C=O)cc1.NC(=O)Nc1cccc(C(F)(F)F)c1>>CC1=C(C(=O)C(C)C)[C@@H](c2ccc(C#N)cc2)NC(=O)N1c1cccc(C(F)(F)F)c1,,C1CCOC1,,,,test
US20150166564A1,Cc1c(-c2nn(C(C)C)c(=O)o2)nn(-c2ccccc2)c1N.O=C(Cl)Oc1ccccc1>>Cc1c(-c2nn(C(C)C)c(=O)o2)nn(-c2ccccc2)c1NC(=O)Oc1ccccc1,,CCOC(C)=O,,[Na+].[OH-],,test
US20160016942A1,CCCCOC(=O)C1(C)CC(c2ccc(NC(=O)c3nc(C#N)cn3COCC[Si](C)(C)C)c(C3=CCC(C)(C)CC3)n2)CC(C)(C)O1>>CC1(C)CC=C(c2nc(C3CC(C)(C)OC(C)(CO)C3)ccc2NC(=O)c2nc(C#N)cn2COCC[Si](C)(C)C)CC1,,C1CCOC1,,CC(C)C[AlH]CC(C)C,,test
US20090137595A1,Cn1cc(Cl)c(C(=O)O)n1.Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)ccc1F>>Cn1cc(Cl)c(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)ccc2F)n1,CN(C)C=O,CC(=O)N(C)C,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US20110071126A1,BrCc1ccc(Br)cc1I.CC(C)(C)OC(=O)N1CC(C#N)C1>>CC(C)(C)OC(=O)N1CC(C#N)(Cc2ccc(Br)cc2I)C1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05929097,COC(=O)c1cc(C)cc(C)c1N(Cc1ccc(Br)cc1)S(=O)(=O)c1ccc(OC)cc1>>COc1ccc(S(=O)(=O)N(Cc2ccc(Br)cc2)c2c(C)cc(C)cc2C(=O)O)cc1,,CCOCC,,,,test
US04272435,CC(C)CC(C)(O)C#N.N>>CC(C)CC(C)(N)C#N,,O,,,,test
US04053615,NO.O=C1CCN(Cc2cccs2)CC1>>NC1CCN(Cc2cccs2)CC1,[Ni],[Na+],[OH-],[Al],,test
US20080027070A1,CC(=O)Nc1ccc(Cl)c(C(=O)Nc2cnc(Nc3ccc(S(=O)(=O)C4CCN(C(=O)OC(C)(C)C)CC4)cc3)nc2)c1>>CC(=O)Nc1ccc(Cl)c(C(=O)Nc2cnc(Nc3ccc(S(=O)(=O)C4CCNCC4)cc3)nc2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090088425A1,CC(c1ccc(OCCCc2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1Cl)C(O)(c1ccnc(Cl)c1)C(F)(F)F>>CC(c1ccc(OCCCc2nnn[nH]2)cc1Cl)C(O)(c1ccnc(Cl)c1)C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160237045A1,CC(C)(C)OC(=O)NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2ccc(-c3ccccc3N)cc2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)CC1.Cl>>Cl.NC[C@@H]1CC[C@@H](C(=O)N[C@@H](Cc2ccc(-c3ccccc3N)cc2)C(=O)Nc2ccc(-c3nn[nH]n3)cc2)CC1,,C1CCOC1,C1COCCO1,,,test
US20140303121A1,Cc1noc(C)c1-c1cnc2[nH]ccc2c1.Fc1cccc(SSc2cccc(F)c2)c1>>Cc1noc(C)c1-c1cnc2[nH]cc(Sc3cccc(F)c3)c2c1,,CN(C)C=O,,O,[H-].[Na+],test
US20050065210A1,CN[C@@H]1CC[C@@H](C(=O)OC)CC1.O=C(Cl)Oc1ccc(Cl)cc1>>COC(=O)[C@@H]1CC[C@@H](N(C)C(=O)Oc2ccc(Cl)cc2)CC1,,c1ccncc1,,Cl,,test
US20060281700A1,O=[N+]([O-])c1ccc(OC2CCCC2)nc1>>Nc1ccc(OC2CCCC2)nc1,[Pd],CO,,,,test
US20160009692A1,COc1ccc(C(C)=O)cc1.O=Cc1ccc(OCc2cn(CC(O)(Cn3cncn3)c3ccc(F)cc3F)nn2)cc1>>COc1ccc(C(=O)/C=C/c2ccc(OCc3cn(CC(O)(Cn4cncn4)c4ccc(F)cc4F)nn3)cc2)cc1,,CO,,[Na+].[OH-],,test
US20010011086A1,O=Cc1ccc2c(c1)C(=O)c1cccc(O)c1-2>>O=C1c2cc(CO)ccc2-c2c(O)cccc21,,C1CCOC1,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US06211234B1,COC(=O)/C(=C/c1ccc(OCc2ccccc2)cc1OCc1ccccc1)NC(=O)c1ccccc1>>O=C(O)/C(=C/c1ccc(OCc2ccccc2)cc1OCc1ccccc1)NC(=O)c1ccccc1,,CO,O,Cl,[K+].[OH-],test
US20110065706A1,C[C@@H]1CNCCN1c1ncc(OCc2ccc(S(C)(=O)=O)cc2)cn1.O=C(OC1CCOC1)ON1C(=O)CCC1=O>>CC1CN(C(=O)O[C@@H]2CCOC2)CCN1c1ncc(OCc2ccc(S(C)(=O)=O)cc2)cn1,,ClCCl,,CCN(CC)CC,Cl,test
US20150110809A1,COC(=O)CC#N.NC(N)=S.O=CC1CCCCC1>>N#Cc1c(C2CCCCC2)nc(S)[nH]c1=O,,CCO,,C1CCNCC1,,test
US20100004246A1,O=C(O)c1nn(-c2cccc([N+](=O)[O-])c2)c(=O)[nH]c1=O>>O=c1cnn(-c2cccc([N+](=O)[O-])c2)c(=O)[nH]1,,c1ccc(Oc2ccccc2)cc1,,,,test
US20080096878A1,CC(C)(C)OC(=O)CBr.Oc1nc2ccccc2[nH]1>>CC(C)(C)OC(=O)Cn1c(=O)[nH]c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20120142717A1,COC(=O)C(C=O)Cc1cnn(C)c1.Cc1ccc(Oc2ccc(CCOC(=N)N)cc2)cc1Cl>>Cc1ccc(Oc2ccc(CCOc3nc(=O)c(Cc4cnn(C)c4)c[nH]3)cc2)cc1Cl,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20120094999A1,CC(=O)N(C)c1ccc(Nc2nc(NC3CCCN(C(=O)OC(C)(C)C)C3)c3ncn(C4CCCCO4)c3n2)cc1.CCO>>CCC(=O)N(C)c1ccc(Nc2nc(NC3CCCNC3)c3nc[nH]c3n2)cc1,,C1COCCO1,Cl,,,test
US20090163534A1,CCOC(=O)Cc1c(C)c(Sc2ccc(S(C)(=O)=O)cc2)n2ccccc12>>Cc1c(CC(=O)O)c2ccccn2c1Sc1ccc(S(C)(=O)=O)cc1,,CO,O,Cl,[Li+].[OH-],test
US04959359,COc1ccc([C@H]2SC(c3ccccc3)=C(C)N(CCN(C)C)C(=O)[C@H]2OC(C)=O)cc1>>COc1ccc([C@H]2SC(c3ccccc3)=C(C)N(CCN(C)C)C(=O)[C@H]2O)cc1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US05834494,CC(C)c1ccc2[nH]ccc2c1>>CC(C)c1ccc2c(c1)CCN2,,CC(=O)O,O,[Na+].[OH-],,test
US20040186140A1,II.OCCc1cccc(C(F)(F)F)c1>>FC(F)(F)c1cccc(CCI)c1,,CC#N,CCOCC,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050272784A1,COC(=O)c1nc(-c2ccc(Br)cc2)oc1-c1ccc(Cl)c(Cl)c1.OB(O)c1ccsc1>>COC(=O)c1nc(-c2ccc(-c3ccsc3)cc2)oc1-c1ccc(Cl)c(Cl)c1,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,C1CCOC1,,[F-].[K+],,test
US20120087880A1,C=CC1(C)CC=C(C)CC1>>CC1=CCC2(C)CCC1C2,,Cc1ccccc1,,O=P(O)(O)O,,test
US20110201643A1,COc1ccc2[nH]c(C(=O)N3CCc4ccc(C(=O)NOC5CCCCO5)cc4C3)cc2c1>>COc1ccc2[nH]c(C(=O)N3CCc4ccc(C(=O)NO)cc4C3)cc2c1,,CO,Cl,,,test
US20050080074A1,O=C1CCC(=O)N1Br.O=C1c2cc(C(F)(F)F)ccc2C[C@@H]2CNCCN12>>O=C1c2cc(C(F)(F)F)cc(Br)c2C[C@@H]2CNCCN12,,O=S(=O)(O)O,,,,test
US20140187533A1,CC(C)(C)N=C=O.NCc1nc2c(C(F)(F)F)cc(C(F)(F)F)cc2[nH]1>>CC(C)(C)NC(=O)NCc1nc2c(C(F)(F)F)cc(C(F)(F)F)cc2[nH]1,,ClCCl,,Cl,,test
US20090143352A1,C1COCCN1.COc1ccccc1-c1cn(S(=O)(=O)c2ccc(C)cc2)c2ncc(-c3cc(Cl)c(N)c(C(=O)O)c3)cc12>>COc1ccccc1-c1c[nH]c2ncc(-c3cc(Cl)c(N)c(C(=O)N4CCOCC4)c3)cc12,,CN(C)C=O,CO,CC(=O)O,[K+].[OH-],test
US20100144723A1,CC(C)(C)OC(=O)NCC(=O)O.NC1CC1>>CC(C)(C)OC(=O)NCC(=O)NC1CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20060142362A1,Nc1ccc(-n2ccccc2=O)cc1F.O=C(Br)CBr>>NC(=O)C(Br)c1ccc(-n2ccccc2=O)cc1F,,C1CCOC1,,CCN(CC)CC,,test
US20070105904A1,Fc1ccnc(Cl)c1.N#Cc1ccc(CO)cc1>>N#Cc1ccc(COc2cc(F)ccn2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20040058978A1,CCOC(=C1C(=O)N(C(C)=O)c2ccccc21)c1ccccc1.CCOC(=O)Cc1ccc(N)cc1>>CCOC(=O)Cc1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1,,CN(C)C=O,,C1CCNCC1,,test
US20100239576A1,CS(=O)(=O)OCCCC1(O)CC1.Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(O)ccc34)c(F)c2)c(=O)n(-c2ccccc2)n1C>>Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(OCCCC5(O)CC5)ccc34)c(F)c2)c(=O)n(-c2ccccc2)n1C,,CC(=O)N(C)C,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050137221A1,COc1ccc(S(=O)(=O)N2C[C@@H](OC(C)=O)[C@H]3OC(C)(C)O[C@@H]3[C@@H]2C(=O)NOCc2ccccc2)cc1>>COc1ccc(S(=O)(=O)N2C[C@@H](O)[C@H]3OC(C)(C)O[C@@H]3[C@@H]2C(=O)NOCc2ccccc2)cc1,,CO,,C[O-].[Na+],,test
US20080119535A1,C=O.COc1cccc(NCc2cnc[nH]2)c1>>COc1cccc(N(C)Cc2cnc[nH]2)c1,,CC#N,,Cl,[BH3-]C#N.[Na+],test
US04163789,COc1cc(NC(=O)C(F)(F)F)c(Cl)cc1C(=O)NC1CCN(CC2CCCCC2)CC1>>COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCCCC2)CC1,,O,,CCO,[Na+].[OH-],test
US20070197532A1,COCC(C)Oc1ccc(OCc2ccccc2)cc1C(=O)OC>>COCC(C)Oc1ccc(OCc2ccccc2)cc1C(=O)O,,CO,,C1CCOC1,[Na+].[OH-],test
US04368156,C=C(C)C(C(=O)OCc1ccc([N+](=O)[O-])cc1)N1C(=O)C(NC(=O)COc2ccccc2)C1S(=O)O.O=C1CCC(=O)N1I>>C=C(C)C(C(=O)OCc1ccc([N+](=O)[O-])cc1)N1C(=O)C(NC(=O)COc2ccccc2)C1I,,ClCCl,,,,test
US20110071126A1,C[Si](C)(C)N=C=N[Si](C)(C)C.N#Cc1cccc(-c2ccc3c(c2)C(=O)C2(Cc4ccccc4C2)C3)c1>>N#C/N=C1\c2cc(-c3cccc(C#N)c3)ccc2CC12Cc1ccccc1C2,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20040143124A1,Cc1nc2cc(N)ccc2s1.O=C1CCC(=O)N1Cl>>Cc1nc2c(Cl)c(N)ccc2s1,,CC(C)O,,,,test
US20080004271A1,NC(=O)c1sc2nc(NC3CC3)nc(-c3cccc(N)c3)c2c1N.O=CCc1ccccc1>>NC(=O)c1sc2nc(NC3CC3)nc(-c3cccc(NCCc4ccccc4)c3)c2c1N,CC(=O)O,CN(C)C=O,,O=C([O-])O.[Na+],,test
US05235055,BrCCCOc1cccc2ncccc12.NCC1COc2cc3c(cc2O1)OCO3>>c1cc(OCCCNCC2COc3cc4c(cc3O2)OCO4)c2cccnc2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20060004017A1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCCC1.Oc1ccc2c(c1)[nH]c1ccccc12>>COc1cc2c(Oc3ccc4c(c3)[nH]c3ccccc34)ncnc2cc1OCCCN1CCCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040220222A1,CN1C(=O)C(NC(=O)OC(C)(C)C)CNc2ccccc21.O=S(=O)(Cl)c1ccccc1>>CN1C(=O)C(NC(=O)OC(C)(C)C)CN(S(=O)(=O)c2ccccc2)c2ccccc21,,ClCCl,,c1ccncc1,,test
US20150239845A1,CC(C)(C)OC(=O)COc1ccc(Nc2cc(=O)[nH]c3ccc(C(c4ccc(Cl)cc4)c4ccc(Cl)cc4)cc23)cc1>>O=C(O)COc1ccc(Nc2cc(=O)[nH]c3ccc(C(c4ccc(Cl)cc4)c4ccc(Cl)cc4)cc23)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070032478A1,Cc1ccccc1C(=O)Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3=CO)c1.Nc1ccc(CN2CCCC2)cc1>>Cc1ccccc1C(=O)Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3=CNc2ccc(CN3CCCC3)cc2)c1,,CCCCCC,CCOC(C)=O,C1CCOC1,,test
US20030166633A1,Brc1ccc2ncnn2c1.C#C[Si](C)(C)C>>C[Si](C)(C)C#Cc1ccc2ncnn2c1,I[Cu]I,C1CCOC1,,CC(C)NC(C)C,,test
US20140213578A1,NCCCN1c2ccccc2CCc2ccc(Cl)cc21.O=S(=O)(Cl)c1ccc(OC(F)(F)F)cc1>>O=S(=O)(NCCCN1c2ccccc2CCc2ccc(Cl)cc21)c1ccc(OC(F)(F)F)cc1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20140256740A1,Cc1noc(C)c1COc1ccc(CC(=O)O)cc1.NC(c1ccccc1Cl)c1ccccc1Cl>>Cc1noc(C)c1COc1ccc(CC(=O)NC(c2ccccc2Cl)c2ccccc2Cl)cc1,,CN(C)C=O,,,,test
US04247715,CCOC(=O)COc1cc2c(c(Cl)c1Cl)C(=O)C(CC#C[Si](C)(C)C)(c1ccc(F)cc1)C2>>O=C(O)COc1cc2c(c(Cl)c1Cl)C(=O)C(c1ccc(F)cc1)C2,,CCO,,[Na+].[OH-],,test
US20100137417A1,COC(=O)CCNC(=O)c1ccc(C(C)Oc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)s1>>CC(Oc1ccc(-c2ccc(C(F)(F)F)cc2)cc1)c1ccc(C(=O)NCCC(=O)O)s1,,CO,,Cl,[Na+].[OH-],test
US20020052359A1,N#CCc1cc(Cl)cc(Cl)c1.O=S(=O)(O)O>>O=C(O)Cc1cc(Cl)cc(Cl)c1,,CCCCCC,,O,,test
US04168282,C1=CC2C3C=CC(C3)C2C1.C1=CCCCC1>>C1=CC2CC1C1CCCCC21,,ClC(Cl)Cl,,,,test
US04071552,CI.O=CNC(CCOc1cccc2ccccc12)COC=O>>COCC(CCOc1cccc2ccccc12)N(C)C=O,,C1CCOC1,,O,[H-].[Na+],test
US04582828,CC1(c2n[nH]c(=O)o2)CC1.Cl[Sn](c1ccccc1)(c1ccccc1)c1ccccc1>>CC1(c2nn([Sn](c3ccccc3)(c3ccccc3)c3ccccc3)c(=O)o2)CC1,,ClCCl,,CCN(CC)CC,,test
US05243010,C[Si](C)(C)Cl.Cc1ccc(C)c(Br)c1>>Cc1ccc(C)c([Si](C)(C)C)c1,,CCOCC,,CCCCCC,[Li]CCCC,test
US05571816,CC(=O)O.CCCCN(C(=O)C(C#N)=CNC(=N)N1CCNC1=O)c1cccc(C(F)(F)F)c1>>C=CC1CN(c2ncc(C(=O)N(C)c3cccc(C(F)(F)F)c3)c(N)n2)C(=O)N1,,CC(=O)O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US03950333,O=C1NC(=O)c2c(CCCBr)cccc21.Sc1ncccn1>>O=C1c2ccccc2C(=O)N1CCCSc1ncccn1,,CCO,,O,[Na],test
US20100256163A1,CCI.Oc1c(C2CCNCC2)cccc1C(F)(F)F>>CCN1CCC(c2cccc(C(F)(F)F)c2O)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US03935209,Brc1ccsc1.Nc1cc(S)ccc1[N+](=O)[O-]>>Nc1cc(Sc2ccsc2)ccc1[N+](=O)[O-],,O,,CN(C)C=O,[H-].[Na+],test
US05036075,O=S1(=O)c2cccc3cccc(c23)N1CCCCl.O=c1[nH]c2ccccc2n1C1CCNCC1>>O=c1[nH]c2ccccc2n1C1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US20110015175A1,CI.Cc1ncn(-c2ccc(NC(N)=S)cc2F)n1>>CSC(=N)Nc1ccc(-n2cnc(C)n2)c(F)c1.I,,CCO,,,,test
US05753665,CC(Br)c1ccnc2ncnn12.Oc1ccc(F)cc1Cl>>CC(Oc1ccc(F)cc1Cl)c1ccnc2ncnn12,,COCCOC,,[H-].[Na+],,test
US20090124802A1,Cc1cc(C)c(Oc2nc(Cl)nc3ccn(C)c23)c(C)c1.N#Cc1ccc(N)cc1>>Cc1cc(C)c(Oc2nc(Nc3ccc(C#N)cc3)nc3ccn(C)c23)c(C)c1,,O,,O=C(O)C(F)(F)F,,test
US20100041721A1,C[C@H](O)[C@@H](N)C(=O)O.N#Cc1ccc(F)c2c(Cl)csc12>>C[C@H](O)[C@@H](Nc1ccc(C#N)c2scc(Cl)c12)C(=O)O,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06107250,C=CCBr.Cc1c(C(F)(F)F)cnn(-c2cc(O)c(Cl)cc2F)c1=O>>C=CCOc1cc(-n2ncc(C(F)(F)F)c(C)c2=O)c(F)cc1Cl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110034469A1,C[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C.N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1c1ccnn1Cc1ccc(F)cc1)C1CCCCC1>>C[C@@H](C(=O)N[C@H](C(=O)N1C[C@H]2CCCN2C[C@H]1c1ccnn1Cc1ccc(F)cc1)C1CCCCC1)N(C)C(=O)OC(C)(C)C,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100249124A1,CCI.O=C1COc2ccccc2N1>>CCN1C(=O)COc2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US03956260,C[C@@H](OC(C)(C)C)[C@H](NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(N)=O>>C[C@@H](OC(C)(C)C)[C@H](NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)CN)C(=O)N1CCC[C@H]1C(N)=O,[Pd],CO,,,,test
US20030236247A1,CN(C)CC[C@H](CSc1ccccc1)Nc1ccc(S(N)(=O)=O)cc1[N+](=O)[O-].O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.O=[N+]([O-])c1ccc(N2CCNCC2)cc1>>CN(C)CC[C@H](CSc1ccccc1)Nc1ccc(S(=O)(=O)NC(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)cc1[N+](=O)[O-],CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20140121206A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1cnc(Cl)cn1>>CC(C)(C)OC(=O)Nc1cnc(Cl)cn1,,C1CCOC1,,,,test
US05082848,Cc1cc2c(c(C)c1[N+](=O)[O-])OCO2>>Cc1cc2c(c(C)c1N)OCO2,[Pd],CCO,,[H][H],,test
US20060094767A1,CC1(COC(=O)Nc2ccc(Cl)cc2)CO1.O=[N+]([O-])c1c[nH]c([N+](=O)[O-])n1>>CC1(COC(=O)Nc2ccc(Cl)cc2)Cn2cc([N+](=O)[O-])nc2O1,,CCO,,CC(=O)[O-].[Na+],,test
US20120135999A1,COC(OC)N(C)C.Cc1c[n+]([O-])c(C)cc1[N+](=O)[O-]>>Cc1cc2[nH]ccc2c[n+]1[O-],[Pd],CCO,CN(C)C=O,,,test
US06143779,CCOc1cc(C=O)ccc1OCc1ccccc1.O=C1COc2cc(O)ccc21>>CCOc1cc(C=C2Oc3cc(O)ccc3C2=O)ccc1OCc1ccccc1,,CO,,Cl,,test
US04472433,CSC1C(=O)Nc2c(Oc3cccc4ccccc34)cccc21>>O=C1Cc2cccc(Oc3cccc4ccccc34)c2N1,[Ni],C1COCCO1,,,,test
US20060128704A1,Nc1cccc(I)c1.O=C(Nc1cccc2c1CC(O)CC2)Oc1ccccc1>>O=C(Nc1cccc(I)c1)Nc1cccc2c1CC(O)CC2,,CS(C)=O,,O,,test
US04330292,CC(=O)Nc1cc([N+](=O)[O-])ccc1OCCCN(C)C>>CC(=O)Nc1cc(N)ccc1OCCCN(C)C,[Pd],CCO,,,,test
US20070167470A1,O=C1CN(CCO)CC12CC2>>OCCN1CC(O)C2(CC2)C1,,CO,,[BH4-].[Na+],,test
US20020035110A1,Brc1cccc2c1C[C@@H]1CNCCN21.COC(=O)CBr>>COC(=O)CN1CCN2c3cccc(Br)c3C[C@@H]2C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20140080808A1,CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(C3(c4ccc(B5OC(C)(C)C(C)(C)O5)cc4)CC3)n2CCS1.Fc1ccc(Br)nc1>>CC1(CO[Si](C)(C)C(C)(C)C)Cc2nnc(C3(c4ccc(-c5ccc(F)cn5)cc4)CC3)n2CCS1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20080221020A1,CCOC(=O)CCOCC(N)(COCCC(=O)OCC)COCCC(=O)OCC.O=C(O)CCNC(=O)OCc1ccccc1>>CCOC(=O)CCOCC(COCCC(=O)OCC)(COCCC(=O)OCC)NC(=O)CCNC(=O)OCc1ccccc1,,ClCCl,,CCN=C=NCCCN(C)C,,test
US04284782,CCN.COC(=O)CC#N.COC(=O)CC(C)=O>>CCn1c(O)cc(C)c(C#N)c1=O,,O,,O=S(=O)(O)O,,test
US05753664,ClCCN1CCOCC1.Cn1c(=O)c2c(ncn2Cc2ccc(C(=O)c3ccc(O)cc3)cc2)n(C)c1=O>>Cn1c(=O)c2c(ncn2Cc2ccc(C(=O)c3ccc(OCCN4CCOCC4)cc3)cc2)n(C)c1=O,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US04496567,CN(C)Cc1cccc(CSCCN)c1.Cc1cc(Cc2cnc(N[N+](=O)[O-])[nH]c2=O)cnc1C>>Cc1cc(Cc2cnc(NCCSCc3cccc(CN(C)C)c3)[nH]c2=O)cnc1C,,CCO,,,,test
US04873251,C[C@@H](C(=O)O)n1c(-c2ccc(Cl)cc2)nc2cccnc21.N>>C[C@@H](C(N)=O)n1c(-c2ccc(Cl)cc2)nc2cccnc21,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20100204231A1,C[C@H](N)c1ccc(F)cc1.Cc1cnc(Nc2nc(Cl)ncc2Cl)s1>>Cc1cnc(Nc2nc(N[C@@H](C)c3ccc(F)cc3)ncc2Cl)s1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20130344030A1,CI.COC(=O)[C@@H]1CCCN(C(=O)OC(C)(C)C)N1C(=O)OC(C)(C)C>>COC(=O)C1(C)CCCN(C(=O)OC(C)(C)C)N1C(=O)OC(C)(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20130244958A1,CC(Cl)OC(=O)Cl.ClCCl.NC1CCOCC1.c1ccncc1>>CC(Cl)OC(=O)NC1CCOCC1.Cl.c1ccncc1,,ClCCl,,,,test
US20100004441A1,CC#N.CN(C)c1ccncc1.O=C(Nc1ncc(Cc2ccc(Cl)cc2Cl)s1)C1CCCN1C(=O)OCc1ccccc1.O=C(ON1C(=O)CCC1=O)ON1C(=O)CCC1=O.OCc1ccncc1>>O=C(NC1CC1)c1ccc(-c2csc(NC(=O)C3CCCN3C(=O)OCc3ccncc3)n2)cc1,CN(C)c1ccncc1,CC#N,ClCCl,CCN(CC)CC,,test
US04335127,CC(=O)c1ccccc1NC(=O)C(Cl)(Cl)Cl.NCCO>>CC(=NCCO)c1ccccc1NC(=O)C(Cl)(Cl)Cl,,CCO,,,,test
US20160115158A1,COc1cc(Cl)cnc1N.O=S(=O)(Cl)c1cnc(Cl)c(Br)c1>>COc1cc(Cl)cnc1NS(=O)(=O)c1cnc(Cl)c(Br)c1,,c1ccncc1,,,,test
US20130281433A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(Br)sc2c1-c1ccc(Cl)cc1.Cc1nn(C)c2cc(B(O)O)ccc12>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccc4c(C)nn(C)c4c3)sc2c1-c1ccc(Cl)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20060004043A1,CCNC(=O)c1ccc2c(c1)c(-c1ccc3cc(OC)ccc3c1)nn2C1CCCCO1>>CCNC(=O)c1ccc2[nH]nc(-c3ccc4cc(OC)ccc4c3)c2c1,,CCO,,,,test
US20070276000A1,CCCC(CC(=O)OCC)Cc1cccc(OC)c1>>CCCC(CC(=O)O)Cc1cccc(OC)c1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20150105373A1,CON(C)C(=O)c1ccc(Br)cc1F.FC(F)(F)Oc1ccc([Mg]Br)cc1>>O=C(c1ccc(OC(F)(F)F)cc1)c1ccc(Br)cc1F,,C1CCOC1,,[Cl-].[NH4+],,test
US20100179312A1,C1COCCN1.OC[C@H]1O[C@@H](n2cnc3c(On4nnc5ccccc54)ncnc32)C[C@@H]1O>>OC[C@H]1O[C@@H](n2cnc3c(N4CCOCC4)ncnc32)C[C@@H]1O,,COCCOC,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04219657,CCOC(=O)C1CCC(=O)C(Sc2ccc(C)cc2)C1>>CCOC(=O)C1CCc2c(sc3ccc(C)cc23)C1,,O,,,,test
US04080451,CCOC(=O)COCC(=O)NN.CN=C=S>>CCOC(=O)COCC(=O)NNC(=S)NC,,C1CCOC1,,,,test
US20100298336A1,Cc1cc(O)nc(S)n1.Cc1ncn(C(C)C)c1CCl>>Cc1cc(O)nc(SCc2c(C)ncn2C(C)C)n1,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20090239862A1,CCOc1cccc(-n2cc(C(=O)C3C(CO)NCCN3C(=O)[O-])nc2-c2ccc(C)cc2)c1.CCOc1cccc(-n2cc(C(=O)N3CCN(C(=O)OCc4ccccc4)C[C@@H]3C(=O)OC)nc2-c2ccc(C)cc2)c1.CO>>CCOc1cccc(-n2cc(C(=O)N3CCNC[C@@H]3COC(C)=O)nc2-c2ccc(C)cc2)c1,,CO,,[BH4-].[Li+],,test
US20110130423A1,CC1(N=C=O)CCOCC1.Cl>>CC1(N)CCOCC1.Cl,,C1CCOC1,,,,test
US20070232594A1,CC(=O)OCCOc1ccc(C(=O)N2CC(=O)N(CC(=O)OCc3ccccc3)Cc3ccccc32)c(Cl)c1.NN>>NNC(=O)CN1Cc2ccccc2N(C(=O)c2ccc(OCCO)cc2Cl)CC1=O,,CCO,,ClCCl,O,test
US05994368,CC(=O)Cl.CNc1ccc(/C=C/C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4ccc(C)nc34)c2Cl)cn1>>CC(=O)N(C)c1ccc(/C=C/C(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4ccc(C)nc34)c2Cl)cn1,,ClCCl,,CCN(CC)CC,O,test
US04605663,CCOC(=O)CCCCCOc1cc2c(c(Cl)c1Cl)C(=O)C(C)(C1CCCC1)C2>>CC1(C2CCCC2)Cc2cc(OCCCCCC(=O)O)c(Cl)c(Cl)c2C1=O,,CC(=O)O,,Cl,,test
US20080261978A1,O=Cc1ccc(C(=O)O)cc1.c1ccc(CNCc2ccccc2)cc1>>O=C(O)c1ccc(CN(Cc2ccccc2)Cc2ccccc2)cc1,CC(=O)O,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100261698A1,N#CCc1ccccc1N.O=C(Cl)c1cccnc1>>N#CCc1ccccc1NC(=O)c1cccnc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100179250A1,CCc1nc(C)c[nH]1.O=C(O)c1cccc(C(=O)O)c1>>CCc1nc(C)c[nH]1.O=C(O)c1cccc(C(=O)O)c1,,CC(C)=O,,,,test
US05360815,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.OCc1cncc(Br)c1>>CC(C)(C)[Si](c1ccccc1)(c1ccccc1)c1ncc(Br)cc1CO,,ClCCl,,c1c[nH]cn1,,test
US20140275030A1,COc1ccc(CN)c(OC)c1.Cc1noc(C)c1-c1cc(C=O)c2[nH]c(=O)n3c2c1OC[C@@H]3c1ccccn1>>COc1ccc(CNCc2cc(-c3c(C)noc3C)c3c4c2[nH]c(=O)n4[C@@H](c2ccccn2)CO3)c(OC)c1,,CCO,,CC(=O)O,[BH3-]C#N.[Na+],test
US05668161,CSc1ccc(C(Br)C(=O)c2ccc(F)cc2)cc1.NC(=S)c1ccccc1Cl>>CSc1ccc(-c2sc(-c3ccccc3Cl)nc2-c2ccc(F)cc2)cc1,,CC#N,,,,test
US20040092582A1,CCCCOc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(Br)c1)=NC(C)(C)C2.OB(O)c1ccncc1>>CCCCOc1cc2c(c3c1OC(C)(C)C3)C(c1cccc(-c3ccncc3)c1)=NC(C)(C)C2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US20150191469A1,Brc1ccnc(Br)n1.C1CN(C2CCOCC2)CCN1>>Brc1nccc(N2CCN(C3CCOCC3)CC2)n1,CN(C)c1ccncc1,CCO,,CCN(C(C)C)C(C)C,Cl,test
US20070032473A1,C=O.O=C(N[C@@H]1CC(=O)N(c2ccc3c(c2)CCNCC3)C1)OCc1ccccc1>>CN1CCc2ccc(N3C[C@H](NC(=O)OCc4ccccc4)CC3=O)cc2CC1,,CC(=O)O,CO,O=C([O-])O.[Na+],,test
US20160024021A1,COC(=O)c1cc(/C=C/c2cnc(Nc3ccc(N4CCNCC4)cc3)nc2)cc(OC)c1.OCCBr>>COC(=O)c1cc(/C=C/c2cnc(Nc3ccc(N4CCN(CCO)CC4)cc3)nc2)cc(OC)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050119325A1,CCN(CC)CC.ClCCCl.N#Cc1cccc2cc(C(=O)O)sc12.On1nnc2ccccc21>>Cl.N#Cc1cccc2cc(C(=O)N[C@H]3CN4CCC3CC4)sc12,,CN(C)C=O,,,,test
US20130324573A1,Cc1ccc(N=C=O)cc1.Oc1ccc2c(c1)N(Cc1ccccc1)CCC2>>Cc1ccc(NC(=O)Oc2ccc3c(c2)N(Cc2ccccc2)CCC3)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20100022516A1,CO.COC(=O)c1c(C)nc(Cl)nc1Cl>>COC(=O)c1c(C)nc(Cl)nc1OC,,CO,,CC(=O)O,C[O-].[Na+],test
US04735940,Cl.[O-][n+]1ccc2ccsc2c1>>Clc1nccc2ccsc12,,C1COCCO1,,O=P(Cl)(Cl)Cl,,test
US20030212111A1,CNCC(=O)OC.S=C=NCc1ccccc1>>CN1CC(=O)N(Cc2ccccc2)C1=S,,CCO,,C1CCC2=NCCCN2CC1,Cl,test
US20100226881A1,CNN.Cc1ccc([N+](=O)[O-])cc1CCl>>Cc1ccc([N+](=O)[O-])cc1CN(C)N,,CCO,,,,test
US20160038504A1,CC(C)C#N.O=C(O)c1cc(Cl)ccn1>>CC(C)(C#N)c1ccnc(C(=O)O)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20160222028A1,CC(=O)Cl.COC(=O)c1ccc2c(c1)OC[C@@H](C(C)C)NC2>>COC(=O)c1ccc2c(c1)OC[C@@H](C(C)C)N(C(C)=O)C2,,ClCCl,,CCN(CC)CC,,test
US20110053959A1,CC(C)C1CCc2ncnc(N3CC4(CCN(Cc5ccccc5)CC4)c4c(CNC(=O)OC(C)(C)C)cccc43)c21.Cl.ClCCl>>CC(C)C1CCc2ncnc(N3CC4(CCN(Cc5ccccc5)CC4)c4c(CN)cccc43)c21.Cl.Cl.Cl,,C1COCCO1,ClCCl,,,test
US06613766B1,Cc1cc(-c2nnc3c4cccnc4c(Cl)nn23)no1.Cn1ncnc1CO>>Cc1cc(-c2nnc3c4cccnc4c(OCc4ncnn4C)nn23)no1,,CN(C)C=O,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20090270473A1,CC(C)CC(C(=O)O)C(=O)NOC(=O)C(C)(C)C.CCCCc1nc(Cl)c(C=O)n1Cc1ccc(S(=O)(=O)NC(=O)CN)cc1>>CCCCc1nc(Cl)c(C=O)n1Cc1ccc(S(=O)(=O)NC(=O)CNC(=O)C(CC(C)C)C(=O)NOC(=O)C(C)(C)C)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140051679A1,COc1cc(B2OC(C)(C)C(C)(C)O2)ccc1OC1CCN(C=O)CC1.O=C(NC(c1ccccc1)C1CC1)c1ccc2[nH]nc(I)c2c1>>COc1cc(-c2n[nH]c3ccc(C(=O)NC(c4ccccc4)C4CC4)cc23)ccc1OC1CCN(C=O)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US05556864,CN1CCCC1CCOc1ccccc1CCc1cccc(Br)c1.Cl>>CN1CCCC1CCOc1ccccc1CCc1cccc(Br)c1.Cl,,C1COCCO1,,,,test
US04330549,Cc1c(C)c2ccc(OCCCBr)cc2oc1=O.ON=C1CCNCC1>>Cc1c(C)c2ccc(OCCCN3CCC(=NO)CC3)cc2oc1=O,,C1COCCO1,,CCN(C(C)C)C(C)C,Cl,test
US05041679,CC(=O)CC(O)CC(C)Sc1ccccc1F>>CC(=O)C=CCC(C)Sc1ccccc1F,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20070010520A1,CC(C)(C)OC(=O)N1CCNCC1.Cn1cnc2ncc(Br)nc2c1=O>>Cn1cnc2ncc(N3CCN(C(=O)OC(C)(C)C)CC3)nc2c1=O,,COCCO,,,,test
US20080021032A1,O=C1NC(=O)c2ccccc21.OCC#CCO>>O=C1c2ccccc2C(=O)N1CC#CCO,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130338140A1,CCOC(=O)[C@H](CCI)O[Si](CC)(CC)CC.COC(=O)CC(=O)OC>>CCOC(=O)[C@H](CCC(C(=O)OC)C(=O)OC)O[Si](CC)(CC)CC,,C1CCOC1,,[H-].[Na+],,test
US20150284401A1,C1CCOC1.O=C(CCl)NC[C@@H](Cc1ccccc1)NC(=O)CCl>>c1ccc(C[C@H]2CN3CCN2CC3)cc1,,C1CCOC1,,,,test
US20140243345A1,CC(C)(C)OC(=O)Nc1ccc(F)cc1NC(=O)c1cnc2cc(N3CCN(C(=O)OC(C)(C)C)CC3)ccc2c1>>Nc1ccc(F)cc1NC(=O)c1cnc2cc(N3CCNCC3)ccc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090291965A1,CC(C)(C)OC(=O)Nc1cn(-c2ccccc2)nc1NC(=O)c1ccc(CNC(=O)Oc2ccc3ccccc3c2)cc1>>Nc1cn(-c2ccccc2)nc1NC(=O)c1ccc(CNC(=O)Oc2ccc3ccccc3c2)cc1,,C1COCCO1,CCOC(C)=O,Cl,,test
US20150291595A1,COc1cc(NS(=O)(=O)Cc2ccc(F)cc2)cc(B2OC(C)(C)C(C)(C)O2)c1.Cc1ccn2nc([C@H](C)Nc3ncnc(N)c3Br)n(-c3ccccc3)c(=O)c12>>COc1cc(NS(=O)(=O)Cc2ccc(F)cc2)cc(-c2c(N)ncnc2N[C@@H](C)c2nn3ccc(C)c3c(=O)n2-c2ccccc2)c1,,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04766125,CCOC(=O)C1CN(CC(=O)Nc2c(Cl)cccc2Cl)CCN1CCCC(c1ccc(F)cc1)c1ccc(F)cc1>>O=C(CN1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)C(C(=O)O)C1)Nc1c(Cl)cccc1Cl,,CC(C)=O,,Cl,O=C([O-])O.[Na+],test
US20140205537A1,CCOC(=O)CC(=O)OCC.COc1ccc(Cl)c([N+](=O)[O-])c1>>CCOC(=O)C(C(=O)OCC)c1ccc(OC)cc1[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20140243302A1,CC(=O)OC[C@H](N=[N+]=[N-])[C@H](COCc1ccccc1)OC(C)=O>>[N-]=[N+]=N[C@@H](CO)[C@@H](O)COCc1ccccc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20020028807A1,CCN1c2ncc(CCO)cc2C(=O)Nc2c(C)cc(Cl)nc21.Oc1ccnc2ccccc12>>CCN1c2ncc(CCOc3ccnc4ccccc34)cc2C(=O)Nc2c(C)cc(Cl)nc21,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150361096A1,C1=COCCC1.CC(C)(C)[Si](C)(C)OCCC(O)c1sc(Cl)nc1Cl>>CC(C)(C)[Si](C)(C)OCCC(OC1CCCCO1)c1sc(Cl)nc1Cl,,ClCCl,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20070191448A1,COc1ccc([Mg]Br)cc1.COc1ccccc1-c1nc(C(=O)N(C)OC)cn1-c1ccc(C)cc1>>COc1ccc(C(=O)c2cn(-c3ccc(C)cc3)c(-c3ccccc3OC)n2)cc1,,C1CCOC1,,,,test
US20110046110A1,Nc1nccs1.O=C(O)c1cccc2ncc(-c3cccc(OC(F)(F)F)c3)nc12>>O=C(Nc1nccs1)c1cccc2ncc(-c3cccc(OC(F)(F)F)c3)nc12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140294898A1,CC(C)(C)OC(=O)CC[C@@H](NC(=O)OCc1ccccc1)C(=O)O.CI>>CN(C(=O)OCc1ccccc1)[C@H](CCC(=O)OC(C)(C)C)C(=O)O,,C1CCOC1,O,CCOC(C)=O,[H-].[Na+],test
US20120277208A1,BrCC1CC1.COC(=O)c1cc(Oc2ccc(NC(=O)OC(C)(C)C)cc2)cc(OC(C)C)c1>>COC(=O)c1cc(Oc2ccc(N(CC3CC3)C(=O)OC(C)(C)C)cc2)cc(OC(C)C)c1,,O,,CN(C)C=O,[H-].[Na+],test
US06479486B2,C#CCO[Si](C)(C)C.O=C1CC[C@H]2[C@H](S(=O)(=O)c3ccccc3)C[C@]1(c1ccccc1)N2Cc1ccccc1>>O=S(=O)(c1ccccc1)[C@@H]1C[C@]2(c3ccccc3)N(Cc3ccccc3)[C@H]1CC[C@@]2(O)C#CCO,,C1CCOC1,,[Li]CCCC,,test
US20040014962A1,CC(C)[C@@H](CNC(=O)OCc1ccc([N+](=O)[O-])cc1)NC(=O)OC(C)(C)C.Cl>>CC(C)[C@H](N)CNC(=O)OCc1ccc([N+](=O)[O-])cc1.Cl,,C1COCCO1,,,,test
US06586441B2,Cc1ccc(COc2nc(N)nc(-c3ccco3)c2C#N)nc1.O=C1CCC(=O)N1Br>>Cc1ccc(COc2nc(N)nc(-c3ccc(Br)o3)c2C#N)nc1,,CN(C)C=O,,,,test
US05578242,CCCCCc1ccc(C(=O)O)cc1.N#Cc1ccc(S)cc1>>CCCCCc1ccc(C(=O)Sc2ccc(C#N)cc2)cc1,CN(C)c1ccncc1,,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US06130220,NOCc1ccccc1.O=C(O)[C@H]1CCCCN1S(=O)(=O)N1CCC(c2c[nH]c3ccc(F)cc23)CC1>>O=C(NOCc1ccccc1)[C@H]1CCCCN1S(=O)(=O)N1CCC(c2c[nH]c3ccc(F)cc23)CC1,CN(C)c1ccncc1,ClCCl,,CN1CCOCC1,Cl,test
US20090076046A1,CC(C)(C)OC(=O)N(Cc1ccccc1F)c1ccc(C=O)cn1.O=S(=O)(c1ccccc1)n1cc(I)c2cc(Cl)cnc21>>CC(C)(C)OC(=O)N(Cc1ccccc1F)c1ccc(C(O)c2cn(S(=O)(=O)c3ccccc3)c3ncc(Cl)cc23)cn1,,C1CCOC1,,CC(C)[Mg]Cl,[Cl-].[NH4+],test
US20080188521A1,C#CC(O)(CC)CC.Cc1cccc(-c2cc(=O)oc3cc(CN=[N+]=[N-])ccc23)c1>>CCC(O)(CC)c1cn(Cc2ccc3c(-c4cccc(C)c4)cc(=O)oc3c2)nn1,I[Cu]I,CCOC(C)=O,,C1CCOC1,,test
US20050032829A1,CCOCc1nc2c(c(C)c(C)n3nnnc23)n1CCNS(C)(=O)=O>>CCOCc1nc2c(N)nc(C)c(C)c2n1CCNS(C)(=O)=O,O=[Pt]=O,O,,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],test
US20060217382A1,COc1cc(Nc2ncc(C(C)N)nn2)cc(OC)c1OC.N#Cc1cccc(C(=O)Cl)c1>>COc1cc(Nc2ncc(C(C)NC(=O)c3cccc(C#N)c3)nn2)cc(OC)c1OC,,ClCCl,,CCN(CC)CC,,test
US20080300242A1,COc1cc(F)ccc1[N+](=O)[O-].CS(=O)(=O)N1CCNCC1>>COc1cc(N2CCN(S(C)(=O)=O)CC2)ccc1[N+](=O)[O-],,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20030064985A1,O=C1C(=Cc2ccc(Cl)c(Cl)c2)C(=O)c2ccccc21.OO>>O=C1c2ccccc2C(=O)C12OC2c1ccc(Cl)c(Cl)c1,,CO,,O,[Na+].[OH-],test
US20020077316A1,CCOC(=O)C(C)(CCCCSCCCCC(C)(C(=O)OCC)c1ccccc1)c1ccccc1>>CC(CCCCSCCCCC(C)(C(=O)O)c1ccccc1)(C(=O)O)c1ccccc1,,CCO,O,[Na+].[OH-],,test
US05726325,CC(=O)Nc1cccc(O)c1.COC(=O)c1sccc1CBr>>COC(=O)c1sccc1COc1cccc(NC(C)=O)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],O=C([O-])O.[Na+],test
US20060154945A1,Brc1csc(-c2ccncc2)c1.O=C1NC[C@@]2(CN3CCC2CC3)O1>>O=C1O[C@]2(CN3CCC2CC3)CN1c1csc(-c2ccncc2)c1,[Cu]I,,,,,test
US06468998B1,BrCCc1ccccc1.O=C(N[C@H]1CCNC1)C12CC3CC(CC(C3)C1)C2>>O=C(N[C@H]1CCN(CCc2ccccc2)C1)C12CC3CC(CC(C3)C1)C2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04254212,CCS(=O)(=O)CCO.O=C(O)c1cc(O)c2ccccc2c1O>>CCS(=O)(=O)CCOc1cc(C(=O)O)c(O)c2ccccc12,,CC#N,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US20150259343A1,CC(C)(C)OC(=O)N1CCN2CCC(C3CC3)c3cccc(c32)C1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N1CCN2CCC(C3CC3)c3cc(Br)cc(c32)C1,,C1CCOC1,,,,test
US20150315172A1,COC(=O)c1cnc(Cl)cc1Nc1cc(C)ccc1Cl.O>>COC(=O)c1c[nH]c(=O)cc1Nc1cc(C)ccc1Cl,,O,,CC(=O)O,,test
US05424472,C=C(C)C(=O)OC(=O)C(=C)C.Sc1ccccc1>>C=C(C)C(=O)Sc1ccccc1,,COC(C)(C)C,O,[Na+].[OH-],,test
US05158966,CC(=O)OCCN1CSC(=Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C1=O>>CC(C)(C)c1cc(C=C2SCN(CCO)C2=O)cc(C(C)(C)C)c1O,,CC#N,,[NH4+].[OH-],,test
US20030162777A1,COc1ccc([N+](=O)[O-])c2cc[nH]c12>>COc1ccc(N)c2cc[nH]c12,[Pd],CCO,,,,test
US04282158,COc1cc(C=O)cc(OC)c1.O=C(C=P(c1ccccc1)(c1ccccc1)c1ccccc1)CCCCO>>COc1cc(C=CC(=O)CCCCO)cc(OC)c1,,c1ccccc1,,,,test
US05665730,Cc1cccc(NC(=O)OC(C)(C)C)c1CCl.Cc1nc2c(N)cccn2c1C=O>>Cc1cccc(NC(=O)OC(C)(C)C)c1CNc1cccn2c(C=O)c(C)nc12,,CC(C)=O,,[I-].[Na+],,test
US20140163219A1,CC(=O)CCl.CC(=O)Oc1ccc(O)c(C#N)c1Cl>>CC(=O)Oc1ccc2oc(C(C)=O)c(N)c2c1Cl,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04772600,CC(C)O.CN(C)c1cccc(NC(=O)Cn2c(-c3ccc(Cl)cc3)nc3cccnc32)c1.Cl>>CN(C)c1cccc(NC(=O)Cn2c(-c3ccc(Cl)cc3)nc3cccnc32)c1.Cl.O,,CC(C)O,,CC(C)OC(C)C,,test
US05008280,CSCCn1c(=N)sc2cc(OC(F)(F)F)ccc21.O=C(OO)c1cccc(Cl)c1>>CS(=O)CCn1c(=N)sc2cc(OC(F)(F)F)ccc21.Cl,,CCO,,,,test
US04243666,CCCCNC(=O)C1CCNCC1.COc1cc2nc(Cl)nc(N)c2cc1OC>>CCCCNC(=O)C1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1.Cl,,CCCCO,,CCN(CC)CC,,test
US20130096130A1,C=CC(=O)OC.C=CCC[C@@H](c1cccc(F)c1F)[C@H](NC(=O)OC(C)(C)C)c1nccnc1Br>>COC(=O)/C=C/CC[C@@H](c1cccc(F)c1F)[C@H](NC(=O)OC(C)(C)C)c1nccnc1Br,,ClCCl,,,,test
US20050176761A1,COC(=O)c1cncc(O)c1.OC1CCCCC1>>COC(=O)c1cccnc1OC1CCCCC1,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140243314A1,CCOC(=O)C=[N+]=[N-].CN1C(=O)C(=O)c2ccccc21>>CCOC(=O)c1c(O)c(=O)n(C)c2ccccc12,,CN(C)C=O,,CCO,,test
US05641777,CN(C)C(N)=S.Cc1ccc(S(=O)(=O)O)cc1.O=C(CBr)C1(c2ccccc2)CCNCC1>>CN(C)c1nc(C2(c3ccccc3)CCNCC2)cs1.Cc1ccc(S(=O)(=O)O)cc1,,CC(C)=O,CCO,Br,O,test
US20060094767A1,C1CCN(C2CCNCC2)CC1.C[C@@]1(Cn2cc([N+](=O)[O-])nc2Cl)CO1>>C[C@](O)(CN1CCC(N2CCCCC2)CC1)Cn1cc([N+](=O)[O-])nc1Cl,,CN(C)C=O,,O,,test
US20140051679A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc(-c3n[nH]c4ccc(NC(=O)C(c5ccsc5)N5CCCC5)cc34)cc2)CC1>>O=C(Nc1ccc2[nH]nc(-c3ccc(OC4CCNCC4)cc3)c2c1)C(c1ccsc1)N1CCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040180925A1,CC1(NC(=O)OC(C)(C)C)CCNCC1.CS(=O)(=O)c1ccc(Cl)nc1>>CC1(NC(=O)OC(C)(C)C)CCN(c2ccc(S(C)(=O)=O)cn2)CC1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US03987052,CCC(=O)NN.S=C1CN=C(c2ccccc2)c2cc(Cl)ccc2N1>>CCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2,,CCO,,,,test
US20090252680A1,C[Si](C)(C)C=[N+]=[N-].Oc1ccc(-c2cn3cc(I)ccc3n2)cc1>>COc1ccc(-c2cn3cc(I)ccc3n2)cc1,,C1COCCO1,CO,,,test
US05965745,COC(=O)c1ccc(Cc2c[nH]c3ccc([N+](=O)[O-])cc23)c(OC)c1.O=C=NS(=O)(=O)Cl>>COC(=O)c1ccc(Cc2cn(C(N)=O)c3ccc([N+](=O)[O-])cc23)c(OC)c1,,ClCCl,,,,test
US20090306016A1,Cc1cccc(OCCCCBr)c1.O=C1NS(=O)(=O)c2ccccc21>>Cc1cccc(OCCCCN2C(=O)c3ccccc3S2(=O)=O)c1,,CN(C)C=O,,[H-].[Na+],,test
US07442702B2,COC(=O)CCc1cccc(CNCc2ccc(-c3cncnc3)cc2)c1.O=S(=O)(Cl)c1ccc(Cl)cc1>>COC(=O)CCc1cccc(CN(Cc2ccc(-c3cncnc3)cc2)S(=O)(=O)c2ccc(Cl)cc2)c1,,CCN(CC)CC,,,,test
US20040220215A1,COC(=O)CC(=O)C(C)Br.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.NC(=O)C=Cc1ccccc1>>COC(=O)Cc1nc(C=Cc2ccccc2)sc1C,,C1CCOC1,,,,test
US06165684,Brc1ccc2ccccc2c1.O=[N+]([O-])c1ccc(Br)cc1>>O=[N+]([O-])c1ccc(-c2ccc3ccccc3c2)cc1,[Cu],,,,,test
US05288720,CCCCc1nc(=O)c2cc(C=O)ccc2[nH]1.c1ccoc1>>CCCCc1nc(=O)c2cc(C(O)c3ccco3)ccc2[nH]1,,C1CCOC1,,[Li]CCCC,,test
US04402729,CCC(Oc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-])C(=O)Cl.NCC1OCCO1>>CCC(Oc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-])C(=O)NCC1OCCO1,,ClCCl,,,,test
US20140031385A1,CCOC(=O)N(CC(OC)OC)C(c1cccs1)P(=O)(OC)OC.ClCCl>>c1cc2ccsc2cn1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,[NH4+].[OH-],,test
US20150252038A1,CI.COC(=O)c1cc(C2CC2)c(O[C@@H]2CCCN([C@@H](CO)c3cc(Cl)cc(Cl)c3)C2)cc1F>>COC[C@@H](c1cc(Cl)cc(Cl)c1)N1CCC[C@@H](Oc2cc(F)c(C(=O)OC)cc2C2CC2)C1,,COCCOC,,O,[H-].[Na+],test
US20030225057A1,C=CCOc1cc2c(cc1Br)C(C)CN(C(=O)C(F)(F)F)CC2>>C=CCOc1cc2c(cc1Br)C(C)CNCC2,,CO,O,[Na+].[OH-],,test
US20050234081A1,CC(C)(C)OC(N)=O.CSc1sc(C#N)cc1S(=O)(=O)c1cccc(N2CCCCC2)c1>>CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(N2CCCCC2)c1,,C1CCOC1,,[Li]CCCC,,test
US20110190255A1,COC(=O)C1(O[Si](C)(C)C)CCCNC1.FC(F)(F)c1c(-c2ccccc2)noc1-c1nc(-c2ccc(C3CO3)cc2)no1>>O=C(O)C1(O)CCCN(CC(O)c2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1,,CO,,,,test
US20120010188A1,COC(=O)c1ccnc(N)c1.O=C(CBr)c1ccc(Br)cc1>>Br.COC(=O)c1ccn2cc(-c3ccc(Br)cc3)nc2c1,,CCO,,,,test
US20130165464A1,COc1ccc(CN(C(C)=O)c2cc(-n3cc(-c4nccn4COCC[Si](C)(C)C)c(-c4ccccc4Cl)n3)c(C)cn2)c(OC)c1>>CC(=O)Nc1cc(-n2cc(-c3ncc[nH]3)c(-c3ccccc3Cl)n2)c(C)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140088100A1,C#CC(=O)O.CC(C)Oc1cc(NC(=O)NCC(F)(F)F)cc(-c2cnc3c(CN)cccn23)c1>>C#CC(=O)NCc1cccn2c(-c3cc(NC(=O)NCC(F)(F)F)cc(OC(C)C)c3)cnc12,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04677129,CCN1C(=O)C2CC(c3ccc([N+](=O)[O-])cc3)(C2)C1=O>>CCN1C(=O)C2CC(c3ccc(N)cc3)(C2)C1=O,[Pd],CO,,,,test
US20080200527A1,CCOC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1CO.NC1CCCCC1>>O=C(NC1CCCCC1)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1CO,,CC(Cl)Cl,ClCCl,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20100069388A1,CC(=O)O.COC(=O)/C=C/c1cnc(NCCNCc2ccccc2)cn1>>COC(=O)/C=C/c1cnc(NCCN(Cc2ccccc2)C(C)=O)cn1,,ClCCl,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20140228577A1,CCN1OC[C@@H](NC(=O)c2ccc(C(=O)C=C(c3cc(Cl)cc(Cl)c3)C(F)(F)F)cc2C)C1=O.NO>>CCN1OCC(NC(=O)c2ccc(C3=NOC(c4cc(Cl)cc(Cl)c4)(C(F)(F)F)C3)cc2C)C1=O,,CC(Cl)Cl,ClCCl,[Na+].[OH-],,test
US20040132727A1,CC(C)C(O)c1ccccc1.COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)OC(c4ccccc4)C(C)C)cc3)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20140275016A1,CC(=O)Nc1cc(Oc2ccc(N)nc2)ccn1.CC(C)C(N)=O.O=C(Cl)C(=O)Cl>>CC(=O)Nc1cc(Oc2ccc(NC(=O)NC(=O)C(C)C)nc2)ccn1,,C1CCOC1,ClCCCl,O,,test
US20100120785A1,CC1(C)OB(c2ccc(CO)c(F)c2)OC1(C)C.Cc1c(CN2CCN(c3nccnc3Cl)CC2)cnn1-c1ccccc1>>Cc1c(CN2CCN(c3nccnc3-c3ccc(CO)c(F)c3)CC2)cnn1-c1ccccc1.Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(=O)N(C)C,,O,O=C([O-])[O-].[K+].[K+],test
US20110059961A1,CCOC(=O)C(N)C#N.O=C(Cl)c1ccccc1>>CCOC(=O)C(C#N)NC(=O)c1ccccc1,,ClCCl,O,O=C([O-])O.[Na+],,test
US20110077235A1,CC(=O)N1CCCNCC1.CC(C)(O)c1ccc(C(=O)Nc2cc3cc(C4CC4)nn3c(Cl)n2)cc1>>CCc1cc2nc(NC(=O)c3ccc(C(C)(C)O)cc3)cc(N3CCCN(C(C)=O)CC3)n2n1,,CN1CCCC1=O,,,,test
US04406907,Cc1ccc(S(=O)(=O)OCCOCC2CC2)cc1.Oc1ccc(Cl)nc1>>Clc1ccc(OCCOCC2CC2)cn1,,CN(C)C=O,O,[H][H],[H-].[Na+],test
US20030069273A1,NNc1ccccc1C(=O)O.O=c1nc(-c2ccccc2O)oc2ccccc12>>O=C(O)c1ccccc1-n1nc(-c2ccccc2O)nc1-c1ccccc1O,,CCO,,,,test
US20040019048A1,CCCCc1nc2cnc3ccccc3c2n1CCCNC(=O)OC(C)(C)C.Cl>>CCCCc1nc2cnc3ccccc3c2n1CCCN.Cl,,C1COCCO1,,,,test
US20030012980A1,Cc1ccc2nc(C)cc(Cl)c2c1.FC(F)(F)c1cc(Br)cc(C(F)(F)F)c1.FC(F)(F)c1cc([Mg]Br)cc(C(F)(F)F)c1>>Cc1ccc2nc(C)cc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)c2c1.FC(F)(F)c1cc([Mg]Br)cc(C(F)(F)F)c1,,C1CCOC1,O,[Mg],,test
US20130252958A1,CI.N#Cc1nn(-c2ccccc2)c(=O)[nH]c1=O>>Cn1c(=O)c(C#N)nn(-c2ccccc2)c1=O,,O,,CN(C)C=O,[H-].[Na+],test
US20090030038A1,COc1ccc(N=C(c2ccccc2)c2ccccc2)c2c1C[C@@H](NC(=O)C(F)(F)F)CC2>>COc1ccc(N)c2c1C[C@@H](NC(=O)C(F)(F)F)CC2,,C1CCOC1,,Cl,,test
US20100105744A1,Br[Mg]C1CC1.CC(=O)c1ccc(C)cc1>>Cc1ccc(C(C)(O)C2CC2)cc1,,C1CCOC1,CCOCC,,,test
US20050107449A1,COC(=O)CCc1ccc(CCl)cc1C.[N-]=[N+]=[N-]>>COC(=O)CCc1ccc(CN=[N+]=[N-])cc1C,,CN(C)C=O,,O,,test
US20120071512A1,CI.O=C1Nc2cccc(Cl)c2C1=O>>CN1C(=O)C(=O)c2c(Cl)cccc21,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04436748,CCC=O.Oc1cc2ccsc2c(Cl)c1Cl>>CCC(O)c1cc2cc(O)c(Cl)c(Cl)c2s1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20050124656A1,CC(C)(C)OC(=O)c1cccc(Br)c1.Cc1ccc(B(O)O)cc1>>Cc1ccc(-c2cccc(C(=O)OC(C)(C)C)c2)cc1,,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20130289029A1,Cc1cc(F)ccc1C#N.Cl.NN>>Cc1cc(NN)ccc1C#N.Cl,,CCO,CCOCC,O,O,test
US04745176,C=C(C)c1ccccc1.Cl>>CC(C)(Cl)c1ccccc1,,ClCCl,,,,test
US20120101134A1,CCOC(=O)CCCc1cccc(-c2cnc(-c3ccc(OC(C)C)c(C#N)c3)s2)c1CC>>CCc1c(CCCC(=O)O)cccc1-c1cnc(-c2ccc(OC(C)C)c(C#N)c2)s1,,CC(C)O,O,[Na+].[OH-],,test
US20020019371A1,CC(O)O.COc1ccc(Br)c(C=O)c1>>COc1ccc(Br)c(C2OCCO2)c1,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,,,test
US20020042537A1,C=CC(=O)OC.CC(C)[N+](=O)[O-]>>COC(=O)CCC(C)(C)[N+](=O)[O-],,CCO,,[F-].[K+],,test
US20040082551A1,O=C(O)/C=C/C(=O)O.OC1CCCC1N1CCC(c2[nH]nc(-c3ccc(Cl)cc3)c2-c2ccncn2)CC1>>O=C(O)/C=C/C(=O)O.OC1CCCC1N1CCC(c2[nH]nc(-c3ccc(Cl)cc3)c2-c2ccncn2)CC1,,CO,,,,test
US20020019382A1,CON.O=C(C=Cc1ccccc1O)C=Cc1ccccc1O>>CON=C(C=Cc1ccccc1O)C=Cc1ccccc1O,,CO,ClC(Cl)Cl,Cl,,test
US07071175B1,Cc1nc(NC(=O)OC(C)(C)C)ccc1C(C)(C)O[SiH2]C(C)(C)C>>Cc1nc(NC(=O)OC(C)(C)C)ccc1CO,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20020115642A1,O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CO)CS[C@H]12.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(COC(=O)Oc3ccc([N+](=O)[O-])cc3)CS[C@H]12,CN(C)c1ccncc1,C1CCOC1,ClCCl,Cc1cccc(C)n1,,test
US20030199550A1,COC(=O)CC[C@@H]1CC[C@@H](CN(C)C(=O)OC(C)(C)C)CC1>>CN(C[C@@H]1CC[C@@H](CCC(=O)O)CC1)C(=O)OC(C)(C)C,,CCO,,[K+].[OH-],,test
US20160264598A1,CC(=O)CCC(=O)N[C@H]1Cc2cccc(C(=O)O)c2OB1O.CCCCO>>CCCCOC(=O)c1cccc2c1OB(O)[C@@H](NC(=O)CCC(C)=O)C2,,C1COCCO1,,Cl,Cl,test
US20030114420A1,CCOC(=O)[C@H]1C[C@@H](O)CN1C(=O)OC(C)(C)C.COS(=O)(=O)c1ccc(C)cc1>>CCOC(=O)[C@H]1C[C@H](OS(=O)(=O)c2ccc(C)cc2)CN1C(=O)OC(C)(C)C,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04242519,COC(=O)C(C)(SC)c1cccc(C2(c3ccccc3)OCCO2)c1>>CSC(C)(C(=O)O)c1cccc(C2(c3ccccc3)OCCO2)c1,,O,,CO,[Na+].[OH-],test
US20070299076A1,[N-]=[N+]=N[C@H]1CN(Cc2ccccc2)C[C@@H]1N=[N+]=[N-]>>[N-]=[N+]=N[C@H]1CN(Cc2ccccc2)C[C@@H]1N,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120295884A1,COC(=O)CBr.NC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(O)ccc12>>COC(=O)COc1ccc2c(C(N)=O)cn(CC(=O)N3C[C@H](F)C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070105943A1,NCc1cccc(Oc2ccccc2)c1.O=C(O)c1ccc2ncsc2c1>>O=C(NCc1cccc(Oc2ccccc2)c1)c1ccc2ncsc2c1,,C1CCOC1,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20060148858A1,COC(=O)Cc1cccc(OC)c1O.Cc1ccc(-n2cc(CCCO)c(C(C)C)n2)nc1>>COc1cccc(CC(=O)O)c1OCCCc1cn(-c2ccc(C)cn2)nc1C(C)C,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20060046999A1,COc1ccc(N)cc1OC.N#CCC(=O)c1ccc(F)cc1>>COc1ccc(NC(=N)CC(=O)c2ccc(F)cc2)cc1OC,,CCO,,,,test
US07030063B1,COC(=O)c1ccc(O)c2ncccc12.FC(F)Cl>>COC(=O)c1ccc(OC(F)F)c2ncccc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05258405,NC1CCCCCC1.O=Cc1ccc2c(c1)Cc1ccccc1-2>>c1ccc2c(c1)Cc1cc(CNC3CCCCCC3)ccc1-2,,O,,CCO,[BH4-].[Na+],test
US20050176706A1,CC(C)(CC(=O)C1(F)CC1)c1ccc(F)cc1.Cc1ccnc2ccccc12>>CC(C)(CC(O)(Cc1ccnc2ccccc12)C1(F)CC1)c1ccc(F)cc1,,C1CCOC1,,[Li],,test
US04009175,CC(C)N(O)C(C)C.O=[N+]([O-])c1ccc2c(c1)C(c1ccccc1Cl)=NCc1nnc(CCl)n1-2>>CC(C)N(Cc1nnc2n1-c1ccc([N+](=O)[O-])cc1C(c1ccccc1Cl)=NC2)C(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20120101127A1,C=C(C)C.CCOC(=O)c1ccc(N=Cc2ccccc2[N+](=O)[O-])cc1>>CCOC(=O)c1ccc2c(c1)C(C)(C)CC(c1ccccc1[N+](=O)[O-])N2,,CC#N,,CCOCC,FB(F)F,test
US20070135490A1,C[Si](C)(C)CCOCCl.OCCc1ccccc1O>>C[Si](C)(C)CCOCOc1ccccc1CCO,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090253917A1,CCOC(=O)C1(N(NC(=O)OCc2ccccc2)C(=O)OCc2ccccc2)CC(=O)NC1=O>>CCOC(=O)C1(N)CC(=O)NC1=O,O=[Pt],CC(=O)O,,[H][H],,test
US20090318408A1,CC(C)(C)OC(=O)N1CCC(N)CC1.COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C>>COc1cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20060257987A1,CCc1ccc(O)c(C(=O)c2ccccc2)c1.Cc1ccc(S(=O)(=O)OCCC(C)O)cc1>>CCc1ccc(OCCC(C)O)c(C(=O)c2ccccc2)c1,,CCOCC,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120220572A1,CC1(C)CNCc2cc([N+](=O)[O-])ccc21.O=S(=O)(OCC(F)(F)F)C(Cl)(Cl)Cl>>CC1(C)CN(CC(F)(F)F)Cc2cc([N+](=O)[O-])ccc21,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20130267510A1,CC1(C)COc2cccc(Oc3ccc(NC(=O)C4(N)CCC4)cn3)c21.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC1(C)COc2cccc(Oc3ccc(N4C(=O)NC5(CCC5)C4=O)cn3)c21,,ClCCl,,CCN(CC)CC,,test
US20150175602A1,CC(C)Nc1nc2c(nc1N1CCC(C(F)c3ccc(F)cc3F)CC1)CNCC2.CN(C)C(=O)Cl.O=C(O)C(F)(F)F>>CC(C)Nc1nc2c(nc1N1CCC(C(F)c3ccc(F)cc3F)CC1)CN(C(=O)N(C)C)CC2.O=C(O)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20150166480A1,CC(C)(F)CN1CCC(COc2ccc(Br)cn2)CC1.COC(=O)c1ccc(B(O)O)cc1>>COC(=O)c1ccc(-c2ccc(OCC3CCN(CC(C)(C)F)CC3)nc2)cc1,,C1COCCO1,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20020028812A1,CCOC(=O)CP(=O)(OCC)OCC.O=[N+]([O-])c1ccc(CBr)cc1>>CCOC(=O)C(Cc1ccc([N+](=O)[O-])cc1)P(=O)(OCC)OCC,,C1CCOC1,,[H-].[Na+],,test
US04290947,COC(=O)C[C@@H]1[C@@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)C(=O)N1[Si](C)(C)C(C)(C)C>>C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1C(=O)N([Si](C)(C)C(C)(C)C)[C@@H]1CC=O,,Cc1ccccc1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20060293319A1,O=C1Nc2cc(Cl)ccc2C1(Cc1cccc(Cl)c1)C1CCCNC1.O=C=Nc1ccncc1>>O=C(Nc1ccncc1)N1CCCC(C2(Cc3cccc(Cl)c3)C(=O)Nc3cc(Cl)ccc32)C1,,Cc1ccccc1,ClCCl,CCN(CC)CC,,test
US20060167012A1,COC(=O)CC1Cc2ccc(S(=O)(=O)N3CCN(c4ccc(C(F)(F)F)cc4)CC3)cc2C1>>O=C(O)CC1Cc2ccc(S(=O)(=O)N3CCN(c4ccc(C(F)(F)F)cc4)CC3)cc2C1,,C1CCOC1,,[Li+].[OH-],,test
US05612356,CC1(C)CCC(C)(C)c2cc(C=O)c(O)cc21.CCOC(=O)c1ccc(C#CCBr)cc1>>CCOC(=O)c1ccc(C#CCOc2cc3c(cc2C=O)C(C)(C)CCC3(C)C)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050288318A1,CI.Cc1ccc(-c2cc3c4cc(C)ccc4[nH]c3n(C)c2=O)c(C)c1>>Cc1ccc(-c2cc3c4cc(C)ccc4n(C)c3n(C)c2=O)c(C)c1,,CN(C)C=O,,[H-].[Na+],,test
US20050239802A1,BrC1=C(Br)CCC1.C[Sn](C)(C)Cl>>C[Sn](C)(C)C1=C(Br)C=CC1,,C1CCOC1,,[Li]CCCC,,test
US20060183736A1,COc1ccc2c(Oc3ccc(O)cc3)c(-c3ccc(S(C)(=O)=O)cc3)ccc2c1.Cl.ClCC=NCCCCCCCl>>COc1ccc2c(Oc3ccc(OCCN4C=CC=CC=C4)cc3)c(-c3ccc(S(C)(=O)=O)cc3)ccc2c1.Cl,,CN(C)C=O,,[H-].[Na+],,test
US20040092737A1,CCOC(=O)CCCSc1ncnc2ncn(Cc3ccc4c(c3)N(COC)c3nccnc3S4)c12>>O=C(O)CCCSc1ncnc2ncn(Cc3ccc4c(c3)Nc3nccnc3S4)c12,,ClCCl,,BrB(Br)Br,O,test
US05506190,CCC(C)(N)c1ccc(Cl)cc1.O=C1C2=CC(CCC2)C(=O)N1c1cc(OC2CCCC2)c(Cl)cc1F>>CCC(C)(NC(=O)C1=C(C(=O)Nc2cc(OC3CCCC3)c(Cl)cc2F)CCCC1)c1ccc(Cl)cc1,,c1ccccc1,,CN1CCOCC1,Cl,test
US20110245257A1,CC(NC(=O)OCc1ccccc1)c1nc2cccnn2c1I.CCCC[Sn](CCCC)(CCCC)c1ccccn1>>CC(NC(=O)OCc1ccccc1)c1nc2cccnn2c1-c1ccccn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US04284642,Cc1cccc(C)c1N.Cc1cccc(C)c1NCC(C)Cl>>Cc1cccc(C)c1NCC(C)Nc1c(C)cccc1C.Cl,,CC(C)O,,[I-].[K+],,test
US20080096874A1,C1COCCN1.O=[N+]([O-])c1cnc(Cl)c(Cl)c1>>O=[N+]([O-])c1cnc(N2CCOCC2)c(Cl)c1,,O,,,,test
US20130115190A1,CC(C)Br.O=c1[nH]nc(Cl)c2ccccc12>>CC(C)n1nc(Cl)c2ccccc2c1=O,,O,,O=C([O-])[O-].[K+].[K+],,test
US20160145271A1,Cc1nc2[nH]nc(-c3nnc4c(n3)NC(=O)C4(C)C)c2cc1F.Fc1c(Cl)cccc1CBr>>Cc1nc2c(cc1F)c(-c1nnc3c(n1)NC(=O)C3(C)C)nn2Cc1cccc(Cl)c1F,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080027092A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1c(Sc2ccc(Cl)cc2)c2c(Cl)nccc2n1CC(=O)O>>Cc1cc2c(Cl)nccc2n1C(=O)OC(C)(C)C,,ClCCl,,,,test
US20100286161A1,CC(C)(C)OC(=O)Nc1ncc(Br)nc1Br.NN>>CC(C)(C)OC(=O)Nc1ncc(Br)nc1NN,,C1COCCO1,,O,,test
US20150252008A1,CC(C)(C)OC(=O)CBr.Nc1cnc(-c2ccc(C3CCC3)c(O)c2F)cn1>>CC(C)(C)OC(=O)COc1c(C2CCC2)ccc(-c2cnc(N)cn2)c1F,,CS(C)=O,,[K+].[OH-],,test
US20060094750A1,CC(C)S(=O)(=O)c1ccc(Cl)c([N+](=O)[O-])c1.NCC1(O)CCOCC1>>CC(C)S(=O)(=O)c1ccc(NCC2(O)CCOCC2)c([N+](=O)[O-])c1,,CCN(CC)CC,,Cl,,test
US20090130076A1,CC(C)(C)OC(=O)NC1CCNCC1.Fc1c(CBr)cc2scnc2c1-c1cccc(Cl)c1>>CC(C)(C)OC(=O)NC1CCN(Cc2cc3scnc3c(-c3cccc(Cl)c3)c2F)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100173901A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.CC1Cc2ccc(Br)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1>>CC1Cc2ccc(C3=CCN(C(=O)OC(C)(C)C)CC3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1,,C1COCCO1,O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20100121052A1,NC(N)=O.Nc1c(F)cc(Br)cc1CO>>Oc1ncc2ccccc2n1,,O,,,,test
US20130317033A1,C[Si](C)(C)c1cc(NN)nnc1Cl.O=C(Cl)c1ccccc1F>>C[Si](C)(C)c1cc(N(N)C(=O)c2ccccc2F)nnc1Cl,,CCOCC,,CCN(CC)CC,,test
US20130040930A1,COC[C@H]1CCC(=O)N1c1ccc(C(=O)N2CCN(c3ncc(C)cc3C)CC2)cc1.Cl>>COC[C@H]1CCC(=O)N1c1ccc(C(=O)N2CCN(c3ncc(C)cc3C)CC2)cc1.Cl,,CCOC(C)=O,,,,test
US20150011580A1,CC1(C)C(=O)N(Br)C(=O)N1Br.CCCCCc1cc(C)c2c(n1)N(C)CC2>>CCCCCc1nc2c(c(C)c1Br)CCN2C,,ClC(Cl)Cl,,,,test
US20110263612A1,Cc1cc2c(C)noc2cc1-c1cnc(N)cn1.O=C(Cl)c1c(F)cccc1F>>Cc1cc2c(C)noc2cc1-c1cnc(NC(=O)c2c(F)cccc2F)cn1,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20150353489A1,CC(C)(C)OC(=O)NCCOCCO.II>>CC(C)(C)OC(=O)NCCOCCI,,ClCCl,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130210844A1,CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)O)n1.Nc1cccc2c(Oc3cccc(C(F)(F)F)c3)nccc12>>CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)Nc2cccc3c(Oc4cccc(C(F)(F)F)c4)nccc23)n1,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US04166860,Cc1cccc(OC(=N)NC#N)c1.NCCc1c[nH]cn1>>N#CNC(=N)NCCc1c[nH]cn1,,CC(C)O,,,,test
US20070254869A1,CC(C)OC(=O)N1CCCC(=NO)c2ccc(Cl)cc21>>CC(C)OC(=O)N1CCCC(N)c2ccc(Cl)cc21,,CN(C)C=O,CO,[Na+].[OH-],,test
US20080045526A1,O=C1OC(=O)c2ncccc21>>O=C1OCc2ncccc21,,C1CCOC1,,CC(=O)O,[BH4-].[Na+],test
US20060094770A1,COC(=O)CCCCCBr.COc1ccc(-n2c(-c3ccccc3)nc3cc(NS(=O)(=O)c4ccc(Cl)cc4)ccc32)cc1>>COC(=O)CCCCCN(c1ccc2c(c1)NC(c1ccccc1)N2c1ccc(OC)cc1)S(=O)(=O)c1ccc(Cl)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US04698348,CNc1c(N)cnc2ccc(C)cc12.O=C(O)C(F)(F)F>>Cc1ccc2ncc3nc(C(F)(F)F)n(C)c3c2c1,,Cl,,[NH4+].[OH-],,test
US06339045B1,COc1cc(Oc2cccc(C(F)(F)F)c2)nc(C(N)=O)c1.O=CC(Cl)(Cl)Cl>>COc1cc(Oc2cccc(C(F)(F)F)c2)nc(C(=O)NC=C(Cl)Cl)c1,,c1ccccc1,,,,test
US05763599,C=O.Cc1ccc(Cl)cc1[N+](=O)[O-]>>O=[N+]([O-])c1cc(Cl)ccc1CCO,,CO,CS(C)=O,,,test
US20120277207A1,CS(=O)(=O)OC1CN(C(c2ccccc2)c2ccccc2)C1.ClCCl.OCCC(F)(F)F>>FC(F)(F)CCCOC1CN(C(c2ccccc2)c2ccccc2)C1,,O,,,,test
US20140018313A1,O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.OC1COC1>>O=C(Oc1ccc([N+](=O)[O-])cc1)OC1COC1,,C1CCOC1,,c1ccncc1,,test
US05859153,Cc1cc(CO)c(O)c(CO)c1.Oc1ccccc1O>>Cc1ccc(O)cc1.Oc1ccccc1O,,O,,O=C(O)C(=O)O,,test
US06350749B1,CC1(C)OC(=O)C(=CNC2=CC(=O)CC(c3ccccc3Cl)C2)C(=O)O1>>O=C1CC(c2ccccc2Cl)Cc2[nH]ccc(=O)c21,,c1ccc(Oc2ccccc2)cc1,,,,test
US20090275578A1,C#CCBr.O=C1NCc2ccccc21>>C#CCN1Cc2ccccc2C1=O,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05254554,CC(=O)OC(C)=O.Cc1c(C(F)(F)F)c(=O)c(O)nn1-c1ccccc1>>CC(=O)Oc1nn(-c2ccccc2)c(C)c(C(F)(F)F)c1=O,,CC(=O)OC(C)=O,,CCOCC,,test
US20050003303A1,C=C(C)C(=O)Cl.CS(=O)(=O)Cl.NC1CCC(O)CC1>>C=C(C)C(=O)OC1CCC(NS(C)(=O)=O)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US20030216402A1,COC(=O)c1ccc(N)c(C(=O)[O-])c1>>Nc1ccc(C(=O)O)cc1C(=O)O,,C1COCCO1,O,Cl,[Li]O,test
US20160016951A1,COCCn1cc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)cn1.CS(=O)(=O)Nc1ccc2cncc(Cl)c2c1>>COCCn1cc(-c2ccc(-c3cncc4ccc(NS(C)(=O)=O)cc34)cc2)cn1,,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20150105373A1,CC(C)(C)OC(=O)NC(CC(N)=O)c1ccc(OC(F)(F)F)cc1>>CC(C)(C)OC(=O)NC(CC#N)c1ccc(OC(F)(F)F)cc1,,C1CCOC1,,O=S(Cl)Cl,,test
US20120258946A1,COC(=O)C(C(=O)OC)c1ccc([N+](=O)[O-])cc1F>>COC(=O)C(C(=O)OC)c1ccc(N)cc1F,,CCO,,,,test
US20020042428A1,O=C(O)c1ccc(Br)s1.Oc1ccccc1>>O=C(O)c1ccc(-c2ccccc2O)s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20100009969A1,CC1CCCN1.O=C(C1CCc2sc(-c3ccc(OCCCCl)cc3)nc21)N1CCCCC1>>CC1CCCN1CCCOc1ccc(-c2nc3c(s2)CCC3C(=O)N2CCCCC2)cc1,,CC#N,,,,test
US20110306542A1,COc1cc(CC(N)C(=O)OC(C)(C)C)ccc1O.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>COc1cc(CC(NC(=O)c2ccc([N+](=O)[O-])cc2)C(=O)OC(C)(C)C)ccc1O,,ClCCl,,,,test
US06177423B1,NO.O=C1OC(=O)c2ccc([N+](=O)[O-])c3cccc1c23>>O=C1c2cccc3c([N+](=O)[O-])ccc(c23)C(=O)N1O,,c1ccncc1,,Cl,,test
US20100009986A1,CCCCC1(N(C)C)CCC(c2c[nH]c3ncccc23)CC1.C[Si](C)(C)Cl>>CCCCC1(N(C)C)CCC(c2c[nH]c3ncccc23)CC1.Cl,,CCOC(C)=O,,,,test
US20080085880A1,CO.CO[C@H]1CC2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@H]([C@H](C)C[C@@H]2CC[C@H](n3cnnn3)[C@H](OC)C2)CC(=O)[C@H](C)C=C(C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=CC=C1C>>CO.CO[C@H]1CC2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@H]([C@H](C)C[C@@H]2CC[C@H](n3cnnn3)[C@H](OC)C2)CC(=O)[C@H](C)C=C(C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=CC=C1C,,CO,,Cc1ccccc1,,test
US05459152,CC(C)(C)OC(=O)NCCn1cc(C(=O)c2ccn3c2CSC3c2cccnc2)c2ccc(-c3ccc(F)cc3)cc21.Cl>>Cl.NCCn1cc(C(=O)c2ccn3c2CSC3c2cccnc2)c2ccc(-c3ccc(F)cc3)cc21,,ClCCl,,C1COCCO1,,test
US04685961,Cc1cc(C)nc(NCn2cncn2)n1.O=C=NS(=O)(=O)c1ccccc1Cl>>Cc1cc(C)nc(N(Cn2cncn2)C(=O)NS(=O)(=O)c2ccccc2Cl)n1,,CC#N,,,,test
US20140171316A1,CNO.Cc1cc(C=O)cc(C(=O)O)c1N>>CO/N=C/c1cc(C)c(N)c(C(=O)O)c1,,CCO,,CC(=O)O,Cl,test
US20120101083A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCN(C(=O)OC(C)(C)C)CC4)no2)cc1C#N.O=C(O)C(F)(F)F>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCNCC4)no2)cc1C#N.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20080293951A1,C=O.CCCN(CCC)CCCCNCc1ccc(C#N)cc1>>CCCN(CCC)CCCCN(C)Cc1ccc(C#N)cc1,,CC(=O)O,CO,[Na+].[OH-],,test
US20120094833A1,CCOC(=O)c1cc2cc(F)cnc2n(C)c1=O>>Cn1c(=O)c(C(=O)O)cc2cc(F)cnc21,,CCO,O,[Li+].[OH-],,test
US05395934,C1CNCCN1.Fc1ccc(C=CCCl)cc1>>Fc1ccc(C=CCN2CCNCC2)cc1,,CCO,,,,test
US07300952B2,CC(C)(C)OC(=O)Nc1sc2cc(-c3ccc(F)cc3)ccc2c1C(N)=O>>NC(=O)c1c(N)sc2cc(-c3ccc(F)cc3)ccc12,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US06514968B1,CCOC=O.Cc1ccc2c(c1)c1c(OCCN)cccc1n2Cc1ccccc1>>Cc1ccc2c(c1)c1c(OCCNC=O)cccc1n2Cc1ccccc1,,ClCCl,,,,test
US20120208817A1,CCOc1cc(C=O)cc([N+](=O)[O-])c1O.NC(N)=O.O=C(Cc1ccccc1)C1CCCC1>>CCOc1cc(C2NC(=O)NC(C3CCCC3)=C2c2ccccc2)cc([N+](=O)[O-])c1O,,CCO,,Cl,,test
US20150291595A1,CS(=O)(=O)Nc1cc(B(O)O)cc(C(F)(F)F)c1.Cc1ccn2nc([C@H](C)Nc3ncnc(N)c3Br)n(-c3ccccc3)c(=O)c12>>Cc1ccn2nc([C@H](C)Nc3ncnc(N)c3-c3cc(NS(C)(=O)=O)cc(C(F)(F)F)c3)n(-c3ccccc3)c(=O)c12,,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US06071935,COC(=O)C(Cc1ccncc1)(Cc1ccncc1)N=C(c1ccccc1)c1ccccc1>>COC(=O)C(N)(Cc1ccncc1)Cc1ccncc1,,C1CCOC1,,Cl,,test
US04886803,COc1ccc(C(=O)N2CCN(CCCl)CC2)cc1OC.O=C(Nc1ccccn1)c1nc2ccccc2[nH]1>>COc1ccc(C(=O)N2CCN(CCn3c(C(=O)Nc4ccccn4)nc4ccccc43)CC2)cc1OC,,CS(C)=O,,[H-].[Na+],[Cl-].[NH4+],test
US20040067981A1,CN(C)C(=O)Cl.NC(=O)C(F)(F)F.Oc1ccc2c(c1)CCN[C@@H]2CCBr>>CN(C)C(=O)Oc1ccc2c(c1)CCN[C@@H]2CCBr.NC(=O)C(F)(F)F,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100130474A1,Nc1cc(-c2ccc(=O)n(C(F)F)c2)n[nH]1.O=C(O)CCCN1CCCCC1>>O=C(CCCN1CCCCC1)Nc1cc(-c2ccc(=O)n(C(F)F)c2)[nH]n1,,CN(C)C=O,,Cl,O=C(n1ccnc1)n1ccnc1,test
US20090017112A1,CC(C)c1cn2ccccc2c1S(=O)(=O)c1ccc(OCCCBr)cc1.NC1CCCCC1>>CC(C)c1cn2ccccc2c1S(=O)(=O)c1ccc(OCCCNC2CCCCC2)cc1,,Cc1ccccc1,O,CCN(CC)CC,,test
US20120184548A1,CCOC(C)=O.CN(C)C=O.COCCCl.O=Cc1ccc(O)c(O)c1>>COCCOc1ccc(C=O)cc1OCCOC,,CN(C)C=O,,[I-].[K+],,test
US05525602,CCc1c(C)c2c(c(N)c1C/C=C(\C)CCC(=O)OC)C(=O)OC2.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCc1c(C)c2c(c(NC(=O)C(F)(F)F)c1C/C=C(\C)CCC(=O)OC)C(=O)OC2,,ClCCl,,,,test
US20110076292A1,CC(C)n1ncnc1-c1cn2c(n1)-c1ccc(C=O)cc1OCC2.CN>>CNCc1ccc2c(c1)OCCn1cc(-c3ncnn3C(C)C)nc1-2,,ClC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100022580A1,Cc1ccc2c(c1)c1c(n2CC#N)CCN(C)C1>>Cc1ccc2c(c1)c1c(n2CCN)CCN(C)C1,,Cc1ccccc1,,CC(C)C[Al+]CC(C)C.[H-],,test
US20070232627A1,CS(=O)(=O)Cl.Nc1ccc(Oc2ccc(C(=O)Nc3ccc(Br)cc3)cc2[N+](=O)[O-])cc1>>CS(=O)(=O)Nc1ccc(Oc2ccc(C(=O)Nc3ccc(Br)cc3)cc2[N+](=O)[O-])cc1,,c1ccncc1,,,,test
US20040087552A1,CC(C)(C)[Si](C)(C)OC[C@H]1CN(CC2(C(=O)OCc3ccccc3)CCCCC2)C[C@@H]1c1cccc(F)c1>>O=C(OCc1ccccc1)C1(CN2C[C@H](c3cccc(F)c3)[C@@H](CO)C2)CCCCC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20160024096A1,CC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2[nH]c1=O.COc1ccc(OC)c(C=O)c1>>COc1ccc(OC)c(C=CC(=O)c2c(-c3ccccc3)c3cc(Br)ccc3[nH]c2=O)c1,,CCO,O,[Na+].[OH-],,test
US04816452,CCOC(=O)/C(=N\OC1CCCCC1)C(=O)CCl.NC(N)=S>>CCOC(=O)/C(=N\OC1CCCCC1)c1csc(N)n1,,CCO,,CN(C)c1ccccc1,,test
US20160145252A1,Clc1ncc(Br)c(Cl)n1.OCC1CCCCO1>>Clc1ncc(Br)c(OCC2CCCCO2)n1,,C1CCOC1,CO,[H-].[Na+],,test
US20110166128A1,CCCCCCCCCCCCCCCCCCCCCCO.C[C@H](NC(=O)OC(C)(C)C)C(=O)O>>CCCCCCCCCCCCCCCCCCCCCCOC(=O)[C@H](C)NC(=O)OC(C)(C)C,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US04034088,CC(=O)OCC1=C(C(=O)O)N2C(=O)C(NC(=O)Cn3ccnc3S(C)=O)C2SC1.Cc1n[nH]c(=S)s1>>Cc1nnc(SCC2=C(C(=O)O)N3C(=O)C(NC(=O)Cn4ccnc4S(C)=O)C3SC2)s1,,O,,Cl,O=C([O-])O.[Na+],test
US20070213359A1,COc1cccc2cc[nH]c12.ClCCCBr>>COc1cccc2ccn(CCCCl)c12,,CS(C)=O,,[K+].[OH-],,test
US05283241,CC(=O)c1ccccc1Br.Cc1ccc([Sn](C)(C)C)cc1>>CC(=O)c1ccccc1-c1ccc(C)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O,,test
US20030130286A1,CCOC(=O)C(=O)c1c(Cl)cncc1Cl.CNc1nc(Nc2ccc(N3CCOCC3)cc2)ncc1N>>Cn1c(=O)c(-c2c(Cl)cncc2Cl)nc2cnc(Nc3ccc(N4CCOCC4)cc3)nc21,,COCCO,,CC(=O)O,,test
US20110144087A1,CC(=O)Cl.COC(=O)c1ccc([C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2O)cc1>>COC(=O)c1ccc([C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O)cc1,,ClCCl,c1ccncc1,Cc1ccccc1,,test
US20120214809A1,c1ccc(CN2CCCCC2CN(c2ccccc2)C2Cc3ccccc3C2)cc1>>c1ccc(N(CC2CCCCN2)C2Cc3ccccc3C2)cc1,,CO,,O=C[O-].[NH4+],,test
US20100292184A1,C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C#N)CC[C@@H]12>>C[C@]12C=CC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C#N)CC[C@@H]12,,C1COCCO1,ClCCl,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20160229872A1,Cc1cccc(-c2nsc3c(=O)[nH]cnc23)c1.O=C1CCC(=O)N1Br>>O=c1[nH]cnc2c(-c3cccc(CBr)c3)nsc12,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20070203072A1,CN1CCCCC=CC2CC2(C(=O)NS(=O)(=O)C2CC2)NC(=O)C2CC(O)CC2C1=O.COc1ccc2c(O)cc(-c3nc(C(C)C)cs3)nc2c1>>COc1ccc2c(OC3CC4C(=O)NC5(C(=O)NS(=O)(=O)C6CC6)CC5C=CCCCCN(C)C(=O)C4C3)cc(-c3nc(C(C)C)cs3)nc2c1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020160992A1,Cc1ncsc1C.O=C(CBr)c1cccs1>>Cc1sc[n+](CC(=O)[SH]2C=CC=C2)c1C.[Br-],,CCO,,COC(C)(C)C,,test
US20090286778A1,CC(C)(C)OC(=O)Nc1cccc(CCc2cccc(N)c2)n1.Clc1ncc(Cl)c(Cl)n1>>CC(C)(C)OC(=O)Nc1cccc(CCc2cccc(Nc3nc(Cl)ncc3Cl)c2)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040116518A1,COC(=O)CBr.NCCCN1CCCC1=O>>COC(=O)CNCCCN1CCCC1=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070004736A1,Cc1ncc2n1C(=O)N(C1CCN(C(=O)CCS(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC1)C2.Cl>>Cc1ncc2n1C(=O)N(C1CCN(C(=O)CCS(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC1)C2.Cl,,CCOCC,CO,,,test
US20100016164A1,CC(C)(CO)CNCc1ccccc1[N+](=O)[O-].S=C(Cl)Cl>>CC1(C)COC(=S)N(Cc2ccccc2[N+](=O)[O-])C1,,ClC(Cl)Cl,,CCN(CC)CC,O,test
US04798833,CCOC(=O)C(CO)CCBr.Nc1nc(Cl)c2[nH]cnc2n1>>CCOC(=O)C(CO)CCn1cnc2c(Cl)nc(N)nc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090298820A1,Cn1cc(C=O)c2c(N3CCC(C(=O)N4CCOCC4)CC3)ccnc21.O=C1COc2cccc(O)c21>>Cn1cc(/C=C2\Oc3cccc(O)c3C2=O)c2c(N3CCC(C(=O)N4CCOCC4)CC3)ccnc21,Cl,CCO,,,,test
US20150119385A1,COC(OC)c1ccc2c(n1)N(C(=O)Nc1ccc(C#N)cn1)CCC2O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>COC(OC)c1ccc2c(n1)N(C(=O)Nc1ccc(C#N)cn1)CCC2O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20030073699A1,CC1CC(Cc2ccccc2)CCN1C(=O)OC(C)(C)C.CCN=C=NCCCN(C)C.O=C(O)c1ccc2[nH]ccc2c1>>C[C@H]1C[C@@H](c2ccccc2)CCN1c1cc2cc(C(N)=O)ccc2[nH]1,,ClCCl,O,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20030130340A1,COc1cccc(SCC(=O)c2cccnc2)c1>>COc1ccc2c(-c3cccnc3)csc2c1,,O,,[Na+].[OH-],,test
US20110301197A1,CNC1CCCc2ccccc21.O=C(O)c1csc(C2(F)CCN(C(=O)Cn3nc(C(F)F)cc3C(F)F)CC2)n1>>CN(C(=O)c1csc(C2(F)CCN(C(=O)Cn3nc(C(F)F)cc3C(F)F)CC2)n1)C1CCCc2ccccc21,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20070032502A1,CC(C)C[C@H]1CN(Cc2ccccc2)CCN1Cc1nc(NCCCN(C)C)c2ccccc2n1.Clc1ccc(C(Cl)c2ccc(Cl)cc2)cc1>>CC(C)C[C@H]1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CCN1Cc1nc(NCCCN(C)C)c2ccccc2n1,,CC#N,ClCCl,[I-].[K+],,test
US20050267095A1,CC(C)(C)OC(=O)N1CCN(CCCOc2ccc(C3(C#N)CCOCC3)cc2)CC1>>N#CC1(c2ccc(OCCCN3CCNCC3)cc2)CCOCC1,,C1COCCO1,,CO,Cl,test
US20140315881A1,Cc1ccc(C(NC(=O)Cc2ccc3oc(C(Cl)c4c(C)noc4C)cc3c2)c2ccccc2)c(C)c1.O=C1c2ccccc2C(=O)N1CCO>>Cc1ccc(C(NC(=O)Cc2ccc3oc(C(OCCN4C(=O)c5ccccc5C4=O)c4c(C)noc4C)cc3c2)c2ccccc2)c(C)c1,,ClCCl,,,,test
US20140275083A1,C[C@H](Nc1nccc(N2C(=O)OC[C@@H]2[C@@H](C)OC(C)(C)C)n1)c1cccc(Oc2ccccc2)c1>>C[C@H](Nc1nccc(N2C(=O)OC[C@@H]2[C@@H](C)O)n1)c1cccc(Oc2ccccc2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040157902A1,CC(C)(C)OC(=O)NC(CC#N)c1ccc(-c2ccccc2)cc1>>N#CCC(N)c1ccc(-c2ccccc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150266891A1,CCOC(=O)Cl.CCOC(=O)c1c(N)sc(-c2ccc([N+](=O)[O-])cc2)c1C>>CCOC(=O)Nc1sc(-c2ccc([N+](=O)[O-])cc2)c(C)c1C(=O)OCC,,Cc1ccccc1,,CCO,,test
US20040058978A1,O=C1Nc2ccc([N+](=O)[O-])cc2/C1=C(/Nc1ccccc1)c1ccc(CN2C(=O)c3ccccc3C2=O)cc1>>NCc1ccc(/C(Nc2ccccc2)=C2/C(=O)Nc3ccc([N+](=O)[O-])cc32)cc1,,CCO,,NN,O,test
US20090137581A1,Cc1cccc2cc(CN)c(-c3ccccc3C(F)(F)F)nc12.Clc1ncnc2nc[nH]c12>>Cc1cccc2cc(CNc3ncnc4[nH]cnc34)c(-c3ccccc3C(F)(F)F)nc12,,CCO,,CCN(C(C)C)C(C)C,,test
US07470680B2,O=C(O)C[C@@H]1Cc2cc(Cl)c3[nH]ncc3c2CN(CC(F)(F)F)C1=O.O=C1NC(=O)C2(CCNCC2)N1>>O=C1NC(=O)C2(CCN(C(=O)C[C@@H]3Cc4cc(Cl)c5[nH]ncc5c4CN(CC(F)(F)F)C3=O)CC2)N1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20020077337A1,C=C(C(=O)O)c1ccccc1.CC(C)(C)OC(=O)N1CCNCC1>>CC(C)(C)OC(=O)N1CCN(CC(C(=O)O)c2ccccc2)CC1,,CC(C)O,,,,test
US20100105906A1,NCC(=O)O.O=C(O)CCc1cc(Cl)c(Oc2ncccc2C(=O)N2CCN(C3CC3)c3ccccc32)cc1Cl>>O=C(O)CNC(=O)CCc1cc(Cl)c(Oc2ncccc2C(=O)N2CCN(C3CC3)c3ccccc32)cc1Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080255105A1,CC(C)(C)OC(=O)N1CC[C@H]1C(=O)Nc1ccc(OC(F)(F)F)c(-c2ccc(C(=O)Nc3ccc(CN4CCN(S(C)(=O)=O)CC4)cc3)cc2)c1>>CS(=O)(=O)N1CCN(Cc2ccc(NC(=O)c3ccc(-c4cc(NC(=O)[C@@H]5CCN5C(=O)O)ccc4OC(F)(F)F)cc3)cc2)CC1,,C1COCCO1,,Cl,O=C([O-])[O-].[K+].[K+],test
US20150064196A1,Brc1ccc(I)nc1.CC(C)(C)OC(=O)N1CC(O)C1>>CC(C)(C)OC(=O)N1CC(Oc2ccc(Br)cn2)C1,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20160050925A1,Cn1cc(C(=O)O)c(C(F)F)n1.FC(F)(F)c1ccn(-c2cccc(CNC3CC3)c2)n1>>Cn1cc(C(=O)N(Cc2cccc(-n3ccc(C(F)(F)F)n3)c2)C2CC2)c(C(F)F)n1,,ClCCl,O=S(Cl)Cl,CCN(CC)CC,,test
US06087380,CCOC(=O)CCN(c1cnn(C)c1)S(=O)(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)N)cc1)n2C>>Cn1cc(N(CCC(=O)O)S(=O)(=O)c2ccc3c(c2)nc(CNc2ccc(C(=N)N)cc2)n3C)cn1,,CO,,Cl,[Na+].[OH-],test
US20130035325A1,CNC(=O)CC#N.O=Cc1ccc2[nH]nc(-c3cccnc3)c2c1>>N#CC(=Cc1ccc2[nH]nc(-c3cccnc3)c2c1)C(N)=O,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20140155415A1,Brc1nccs1.O=S(=O)(N=Cc1cc2ccccc2o1)c1ccc2c(c1)OCCCO2>>O=S(=O)(NC(c1cc2ccccc2o1)c1nccs1)c1ccc2c(c1)OCCCO2,,C1CCOC1,O,CCCCCC,[Li]CCCC,test
US20120165322A1,CCOC(=O)C(=O)CBr.N#Cc1ccnc(N)c1>>CCOC(=O)c1cn2ccc(C#N)cc2n1,,C1CCOC1,,,,test
US20160120863A1,Clc1ccc(-c2nc3ccc(Br)cn3c2CN2CCOCC2)cc1.OB(O)c1ccccc1F>>Fc1ccccc1-c1ccc2nc(-c3ccc(Cl)cc3)c(CN3CCOCC3)n2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20010023249A1,CC(C)CCN(c1ccc(OCc2ccccc2)cc1)C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)CCN(c1ccc(O)cc1)C1CCN(C(=O)OC(C)(C)C)CC1,[Pd],C1CCOC1,CO,,,test
US20050075334A1,CN(C)C(=S)Cl.O=c1[nH]c2cccc(O)c2[nH]1>>CN(C)C(=S)Oc1cccc2[nH]c(=O)[nH]c12,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130338081A1,CC(C)(C)OC(=O)N1Cc2cc([N+](=O)[O-])ccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21>>CC(C)(C)OC(=O)N1Cc2cc(N)ccc2C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21,[Pd],CO,,,,test
US20160272632A1,CN(C)S(=O)(=O)c1cccc(Nc2nn(C3(CC#N)CCN(C(=O)OC(C)(C)C)CC3)c3ccnc(OCc4ccccc4)c23)c1>>CN(C)S(=O)(=O)c1cccc(Nc2nn(C3(CC#N)CCNCC3)c3ccnc(OCc4ccccc4)c23)c1,,ClCCl,,,,test
US20110144066A1,CCOC(=O)Cc1nnc(NS(=O)(=O)c2ccc(NC(C)=O)cc2)s1>>CC(=O)Nc1ccc(S(=O)(=O)Nc2nnc(CC(=O)O)s2)cc1,,C1CCOC1,,[Li+].[OH-],,test
US20120295884A1,CCOC(=O)[C@@H]1CC(C=O)=CN1C(=O)OC(C)(C)C>>CCOC(=O)[C@@H]1CC(CO)=CN1C(=O)OC(C)(C)C,,ClCCl,,CO,[BH4-].[Na+],test
US20120142705A1,CN(C)C=O.Nc1ccccn1.O=C1C(=O)N(C(CC2CCCC2)C(=O)O)c2ccccc21>>Cn1ccc(NC(=O)C(CC2CCCC2)N2C(=O)C(=O)c3ccccc32)n1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20040077668A1,CC(C)C(NCC(C)(C)N)c1nc2cc(Cl)ccc2c(=O)n1Cc1ccccc1.Cc1cc(C(=O)Cl)ccc1F>>Cc1cc(C2=NC(C)(C)CN2C(c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)ccc1F,,ClCCl,,CCN(CC)CC,,test
US04267176,COC(=O)c1cc(N)ccn1.O=CO>>COC(=O)c1cc(NC=O)ccn1,,O=CO,,CC(=O)OC(C)=O,,test
US20100234374A1,C1CCOC1.CCCCCC(=O)N(C)OC.C[Si](C)(C)CCOCn1cnc(-c2ccc3ccccc3c2)c1.O.[Li]CCCC>>CCC1(CCCCCC(=O)c2nc(-c3ccc4ccccc4c3)cn2COCC[Si](C)(C)C)OCCO1,,CCCCCC,,,,test
US20050197350A1,CCc1cnc(Cl)nc1Cl.CNC>>CCc1cnc(Cl)nc1N(C)C,,C1CCOC1,,,,test
US20060058834A1,C1COCCO1.C[C@H](N)C(=O)O.O=C(O)CO.O=C1CCCCCO1>>O=C1CCCCCO1.O=C1COC(=O)CO1,,C1COCCO1,,,,test
US20080153810A1,CN1CCN(c2n[nH]c3ccc(N)cc23)CC1.O=C(O)Cc1ccc(Oc2ccccc2)cc1.On1nnc2ccccc21>>CN1CCN(c2n[nH]c3ccc(NC(=O)Cc4ccc(OCc5ccccc5)cc4)cc23)CC1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,ClCCCl,test
US20140349972A1,CCCP(=O)(OCC)c1ccc(C(NC(=O)c2cnc(-n3cccn3)nc2O)c2ccccc2)cc1>>CCCP(=O)(O)c1ccc(C(NC(=O)c2cnc(-n3cccn3)nc2O)c2ccccc2)cc1,,C1COCCO1,,[Na+].[OH-],,test
US20060211689A1,CN1CCN(c2ccc(N)c(C(=O)O)c2)CC1.O=C(Cl)OC(Cl)(Cl)Cl>>CN1CCN(c2ccc3[nH]c(=O)oc(=O)c3c2)CC1,,C1COCCO1,,O,,test
US20100016287A1,ClCCCBr.Cn1c(C2CCOCC2)n[nH]c1=S>>Cn1c(SCCCCl)nnc1C1CCOCC1,,CCO,,CC(=O)O,,test
US20070043064A1,CCCCN(c1cccc(C(=O)C=CN(C)C)c1)S(=O)(=O)c1ccc(OC)cc1.Nc1[nH]ncc1[N+](=O)[O-]>>CCCCN(c1cccc(-c2ccnc3c([N+](=O)[O-])cnn23)c1)S(=O)(=O)c1ccc(OC)cc1,,CC(=O)O,,CCOC(C)=O,,test
US20110183998A1,CC(C#Cc1ccc(Oc2ccc(OCc3ccccc3)nc2)cc1)N1C(=O)c2ccccc2C1=O>>CC(N)C#Cc1ccc(Oc2ccc(OCc3ccccc3)nc2)cc1,,CCO,,NN,O,test
US20130158003A1,C#CCSc1nnc(-c2ccncc2)[nH]1>>c1cc(-c2nnc[nH]2)ccn1,[Ni],CCO,,,,test
US20080009488A1,Nc1ccc(C2(O)c3ccccc3C(=O)N2Cc2ccccc2)cc1[N+](=O)[O-]>>Nc1ccc(C2(O)c3ccccc3C(=O)N2Cc2ccccc2)cc1N,[Pd],,,,,test
US06191124B1,Cc1csc2ncc(C(=O)CC(C)c3ccccc3)n12>>Cc1csc2ncc(C(O)CC(C)c3ccccc3)n12,,CCO,,[BH4-].[Na+],,test
US20140275085A1,CC(C)N.COc1nc(Cl)ncc1Br>>COc1nc(NC(C)C)ncc1Br,,C1CCOC1,,O,,test
US20050215793A1,O=P(O)(O)C(O)(Cc1cccnc1)P(=O)(O)O.[Na+]>>O=P([O-])(O)C(O)(Cc1cccnc1)P(=O)(O)O.[Na+],,CC(C)(C)O,,O,,test
US20060041003A1,C=CCCCBr.CCCCC1Cc2cc(OCOC)ccc2C1=O>>C=CCCCC1(CCCC)Cc2cc(OCOC)ccc2C1=O,,CN(C)C=O,,[H-].[Na+],,test
US20070010520A1,Nc1nc(C#CC2(O)CCNCC2)cn2nc(-c3ccco3)nc12.O=Cc1c(F)cc(F)cc1F>>Nc1nc(C#CC2(O)CCN(Cc3c(F)cc(F)cc3F)CC2)cn2nc(-c3ccco3)nc12,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20060009427A1,C1CCOC1.N#Cc1ccc(F)cc1Cl.OC1CCC(O)C1>>CC1CCC(Oc2ccc(C#N)c(Cl)c2)C1,,CC(C)(C)O,,CC(C)(C)[O-].[K+],,test
US20150291655A1,C=CC[Mg]Br.CS(=O)(=O)OC1CCC(=O)CC1>>C=CCC1(O)CCC(OS(C)(=O)=O)CC1,,C1CCOC1,,,,test
US20110319277A1,C=CC(N)=O.COC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)N=Cc1ccccc1>>O=C1CCC(CCCCNC(=O)OCc2ccccc2)(N=Cc2ccccc2)C(=O)N1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US04233302,CN(C)Cc1ccc(CSCCN)o1.S=C=S>>CN(C)Cc1ccc(CSCCN=C=S)o1,,CC(C)=O,,CCN(CC)CC,,test
US06498251B1,CN(C)C(=O)n1c2c(c3ccccc31)CCN(C(=O)OC(C)(C)C)C2.Cl>>CN(C)C(=O)n1c2c(c3ccccc31)CCNC2.Cl,,CO,,,,test
US20110034454A1,CC(C)N.ClCc1cc(N2CCOCC2)nc(-c2ccccn2)n1>>CC(C)NCc1cc(N2CCOCC2)nc(-c2ccccn2)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05364871,CC(=O)NCc1cccc(C(=O)CBr)n1.NC(=S)N=C(N)N>>NCc1cccc(-c2csc(N=C(N)N)n2)n1,,CO,,Br,,test
US20070004786A1,CCC(=O)c1cc(I)c[nH]1.FC(F)(F)CI>>CCC(=O)c1cc(I)cn1CC(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06140330,CCOC(=O)CBr.COc1cc(C=S)ccc1C(=O)N(C)C>>CCOC(=O)Cc1ccc(C=S)cc1OC,,CCO,O,Cl,[Na+].[OH-],test
US20100130446A1,Cc1cc(C(CC2CCOCC2)c2ccc(S(=O)(=O)C3CC3)cc2)[nH]c1-c1ccc(C(C)O[Si](C)(C)C(C)(C)C)cn1>>Cc1cc(C(CC2CCOCC2)c2ccc(S(=O)(=O)C3CC3)cc2)[nH]c1-c1ccc(C(C)O)cn1,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130296555A1,NNC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1.O=C(Cl)N1CCOCC1>>NN(C(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1)C(=O)N1CCOCC1,CN(C)c1ccncc1,ClCCl,,Cl,c1ccncc1,test
US20060004213A1,C=C(C)C(OC(C)=O)OC(C)=O.COc1ccc(OC)cc1>>COc1ccc(OC)c(CC(C)=COC(C)=O)c1,,CCOC(C)=O,,,,test
US20070078121A1,CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)n(-c2cccc(CC(=O)O)c2)n1.NCCO>>CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)n(-c2cccc(CC(=O)NCCO)c2)n1,,C1CCOC1,,CCN(CC)CC,,test
US05021413,CN1CCNC(CN2CCCC2)C1.Cc1ccc2c(c1)C(=O)CC2C(=O)Cl.Cl.Cl>>Cc1ccc2c(c1)C(=O)CC2C(=O)N1CCN(C)CC1CN1CCCC1.Cl.Cl,,CCN(CC)CC,,Cl,,test
US20040242613A1,CC(C)(C)OC(=O)NCC1CCC(CNC(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)NCC1CCC(CN)CC1,,CCO,,C1COCCO1,Cl,test
US20140206681A1,COC(=O)c1ccc(CCO)nc1>>COC(=O)C1CCC(CCO)NC1,,CC(=O)O,,[BH3-]C#N.[Na+],,test
US20070276138A1,COCC(=O)OC.O=Cc1ccc(OCCCOc2ccc(-c3ccccc3)cc2)c(F)c1>>COC(=O)C(OC)C(O)c1ccc(OCCCOc2ccc(-c3ccccc3)cc2)c(F)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US05712300,CC(C)CC1(C(CCN2C(=O)c3ccccc3C2=O)C(=O)OC(C)(C)C)CCN(Cc2ccccc2)C1=O>>CC(C)CC1(C(CCN2C(=O)c3ccccc3C2=O)C(=O)O)CCN(Cc2ccccc2)C1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140221345A1,CC(C)(C)OC(=O)N1CCC(OS(C)(=O)=O)CC1.CC(C)(C)[Si](C)(C)Oc1ccc2[nH]ncc2c1>>CC(C)(C)OC(=O)N1CCC(n2ncc3cc(O)ccc32)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US20140200227A1,CC(=O)OC1CCc2c1ncc(N)c2N1CCC[C@H](NC(=O)OC(C)(C)C)C1.CSc1cc(F)c(-c2nc(C(=O)O)ccc2F)c(F)c1>>CSc1cc(F)c(-c2nc(C(=O)Nc3cnc4c(c3N3CCC[C@H](NC(=O)OC(C)(C)C)C3)CCC4OC(C)=O)ccc2F)c(F)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080009530A1,CCCCCS(N)(=O)=O.O=C(O)CCc1cc(OCc2ccccc2)nn1Cc1ccc(Cl)cc1Cl>>CCCCCS(=O)(=O)NC(=O)CCc1cc(OCc2ccccc2)nn1Cc1ccc(Cl)cc1Cl,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20080255155A1,O=C(Nc1cccc(Oc2ccc([N+](=O)[O-])nc2)c1)N1CCN(c2ccccc2)C1=O>>Nc1ccc(Oc2cccc(NC(=O)N3CCN(c4ccccc4)C3=O)c2)cn1,[Fe],CO,O,[Cl-].[NH4+],,test
US20110015175A1,Cc1ncn(-c2c(F)cc([N+](=O)[O-])cc2F)n1>>Cc1ncn(-c2c(F)cc(N)cc2F)n1,[Pd],CO,,,,test
US20160159808A1,CCOC(=O)CN=C(c1ccccc1)c1ccccc1.Fc1cc(Br)ccc1C(F)(F)F>>CCOC(=O)C(N=C(c1ccccc1)c1ccccc1)c1ccc(C(F)(F)F)c(F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,Cc1ccccc1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20100292255A1,CC(C)(C)OC(=O)N[C@@H](CC(N)=O)C(=O)ON1C(=O)CCC1=O.Nc1ncnc2c1nc(Sc1cc3c(cc1Br)OCCO3)n2CCC1CCNCC1>>NC(=O)C[C@H](N)C(=O)N1CCC(CCn2c(Sc3cc4c(cc3Br)OCCO4)nc3c(N)ncnc32)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US20080051387A1,O=CC1CCCCC1.c1nc2c(c(N3CCN(C4CCC4)CC3)n1)CCNC2>>c1nc2c(c(N3CCN(C4CCC4)CC3)n1)CCN(CC1CCCCC1)C2,,CC(=O)O,ClCCl,O=C([O-])[O-].[Na+].[Na+],,test
US06245746B1,CC(C)(C)OC(=O)N[C@@H](CCCNC(=O)OCc1ccccc1)COS(C)(=O)=O.Sc1nc2ccccc2s1>>CC(C)(C)OC(=O)N[C@@H](CCCNC(=O)OCc1ccccc1)C(=O)Sc1nc2ccccc2s1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20080242655A1,COc1ccc(CN)cc1.N#Cc1cnccc1Cl>>COc1ccc(CNc2ccncc2C#N)cc1,,CC(C)O,,O=C([O-])[O-].[K+].[K+],,test
US05169426,CCCC(=O)C1C(=O)CC(C2CCC3OC3C2)CC1=O.CCON>>CCCC(=NOCC)C1=C(O)CC(C2CCC3OC3C2)CC1=O,,CO,,,,test
US20140051676A1,CC(C)OS(C)(=O)=O.CN(c1ccccc1)c1nc(N)nc(-c2noc(N3CC(O)C3)n2)n1>>CC(C)OC1CN(c2nc(-c3nc(N)nc(N(C)c4ccccc4)n3)no2)C1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20130336965A1,C[C@H]1C[C@@H](c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)C[C@@H](NC(=O)OC(C)(C)C)[C@H]1[S@@](C)=O>>C[C@H]1C[C@@H](c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)C[C@@H](N)[C@H]1[S@@](C)=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120309755A1,NCC(F)F.O=C(N[C@@H]1CC[C@@H](C(F)(F)F)CC1)c1cc([N+](=O)[O-])c(Cl)nc1OCC(F)F>>O=C(N[C@@H]1CC[C@@H](C(F)(F)F)CC1)c1cc([N+](=O)[O-])c(NCC(F)F)nc1OCC(F)F,,CO,,C1CCOC1,,test
US06169107A,COC(=O)c1cc2cccc(O)c2n1C.NC(=O)CCl>>COC(=O)c1cc2cccc(OCC(N)=O)c2n1C,,CN(C)C=O,,[H-].[Na+],,test
US04755212,CCOC(=O)C(Cl)C(C)=O.Nc1n[nH]c(SCc2ccccc2)n1>>Cc1nc2nc(SCc3ccccc3)nn2c(O)c1Cl,,CC(=O)O,,,,test
US20050283021A1,BrCc1ccccc1.CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O,,CO,,O,C[O-].[Na+],test
US04665067,CC(=O)O[C@@H]1NC(=O)[C@H]1NC(c1ccccc1)(c1ccccc1)c1ccccc1.COC(=O)CS>>COC(=O)CS[C@H]1NC(=O)[C@H]1NC(c1ccccc1)(c1ccccc1)c1ccccc1,,CO,,[Na],,test
US20160102059A1,COCCOCCOCCO.N#Cc1cc([N+](=O)[O-])ccc1F>>COCCOCCOCCOc1ccc([N+](=O)[O-])cc1C#N,,CN1CCCC1=O,,[H-].[Na+],,test
US20030125370A1,Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1CC(=O)O.NCCNCC(F)(F)F>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1CC(=O)NCCNCC(F)(F)F,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US05922716,CCOC(=O)CC1(C)C=CC=C2C=c3[nH]c(=O)c(=O)[nH]c3=C21>>CC1(CC(=O)O)C=CC=C2C=c3[nH]c(=O)c(=O)[nH]c3=C21,,C1COCCO1,,Cl,,test
US05098930,CC1CC(O)(c2cc(F)cc(OCc3ccccc3)c2)CCO1.CI>>COC1(c2cc(F)cc(OCc3ccccc3)c2)CCOC(C)C1,,CN(C)C=O,,[H-].[Na+],,test
US05554706,C=CC(=O)Cl.N#Cc1ccc(-c2ccc(OCCCCCCO)cc2)cc1>>C=CC(=O)OCCCCCCOc1ccc(-c2ccc(C#N)cc2)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20130131137A1,COC(=O)c1ccc(C(=O)O)cc1C.C[Si](C)(C)CN>>COC(=O)c1ccc(C(=O)NC[Si](C)(C)C)cc1C,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2cc(F)ccc23)cc1.Nc1ccc(N2CCOCC2)cc1>>Fc1ccc2c(c1)nc(Nc1ccc(N3CCOCC3)cc1)c1[nH]ncc12,C1COCCO1,CO,,Cl,,test
US20160009726A1,CCN(C(C)C)C(C)C.CN(C)C=O.C[C@H]1CN(c2ccncc2N)C[C@@H](NC(=O)[O-])[C@@H]1O[Si](C)(C)C(C)(C)C.O=C(O)c1ccc2occ(Br)c2n1>>C[C@H]1CN(c2ccncc2NC(=O)c2ccc3occ(Br)c3n2)C[C@@H](NC(=O)OC(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20150197512A1,CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2[nH]1.CI>>CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2n1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070259886A1,COc1ccc(CN2Cc3cc(Cl)c(OC)cc3C2)cc1>>COc1cc2c(cc1Cl)CNC2,,O=C(O)C(F)(F)F,,COc1ccccc1,,test
US07317014B2,Clc1nc(Cl)c(-c2ccccc2)c(-c2ccccc2)n1.NN>>NNc1nc(Cl)nc(-c2ccccc2)c1-c1ccccc1,,CCO,,O,,test
US20140336185A1,Cc1ccc(-c2ccc(C#N)cc2)cc1.NN>>Cc1ccc(-c2ccc(C(N)=NN)cc2)cc1,,C1CCOC1,,O,[Li]CCCC,test
US20120122840A1,Cc1cc(OCCN2CCOCC2)ccc1[N+](=O)[O-]>>Cc1cc(OCCN2CCOCC2)ccc1N,[Pd],CO,,,,test
US20050148604A1,COC(=O)c1ccc(O)cc1O.COCCO>>COCCOc1ccc(C(=O)OC)c(O)c1,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150336962A1,CCOC(=O)CN.O=C(Nc1cn(CCBr)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12>>CCOC(=O)CNCCn1cc(NC(=O)c2cnn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1,,CCO,,CCN(CC)CC,Cl,test
US20120190859A1,COC(=O)c1cc(N)c(F)c(Br)n1.COc1c(Cl)ccc(B2OCCCO2)c1F>>COC(=O)c1cc(N)c(F)c(-c2ccc(Cl)c(OC)c2F)n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,[F-].[K+],,test
US20130317026A1,C=C(OCC)c1cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c2cnn(C(C)C)c2n1>>CC(=O)c1cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c2cnn(C(C)C)c2n1,,CO,ClCCl,Cl,O=C([O-])O.[Na+],test
US20120142681A1,CC(=O)c1ccc2nnc(C(F)(F)c3ccc4ncccc4c3)n2n1.NNC(=O)CN1CCOCC1>>C/C(=N\NC(=O)CN1CCOCC1)c1ccc2nnc(C(F)(F)c3ccc4ncccc4c3)n2n1,,CO,,,,test
US20110237573A1,Nc1ccc(-c2cnccn2)cn1.O=C(O)Cc1ccc(-c2ccnc(F)c2)nc1>>O=C(Cc1ccc(-c2ccnc(F)c2)nc1)Nc1ccc(-c2cnccn2)cn1,CN(C)c1ccncc1,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20060079526A1,CNC(=O)c1cc(Oc2ccc(-c3cnnc(N)n3)cc2)ccn1.O=S(=O)(Cl)c1ccc(Cl)c(C(F)(F)F)c1>>CNC(=O)c1cc(Oc2ccc(-c3cnnc(NS(=O)(=O)c4ccc(Cl)c(C(F)(F)F)c4)n3)cc2)ccn1,,c1ccncc1,,,,test
US20140221435A1,COC(=O)c1ccc(N)cn1.O=C(Cl)c1cc(Cl)c(Cl)cc1F>>COC(=O)c1ccc(NC(=O)c2cc(Cl)c(Cl)cc2F)cn1,,CCCCCC,ClCCl,Cl,c1ccncc1,test
US20120295882A1,CC(C)(C)OC(=O)N1CCC2c3cc(S(=O)(=O)c4cccc(Cl)c4)ccc3OC2C1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=S(=O)(c1cccc(Cl)c1)c1ccc2c(c1)C1CCNCC1O2,,ClCCl,,,,test
US20090181948A1,CSC(SC)=C(C#N)C#N.NCCCNCCCO>>N#CC(C#N)=C1NCCCN1CCCO,,C1CCOC1,,CC(C)OC(C)C,,test
US20140171408A1,N#Cc1cc(Cl)c(C(=O)Nc2ccnc(Cl)c2F)c(Cl)c1.O=S(Cl)Cl>>N#Cc1cc(Cl)c(C(Cl)=Nc2ccnc(Cl)c2F)c(Cl)c1,,Cc1ccccc1,,,,test
US20120208819A1,COCCOC.Nc1ncc(Br)nc1C(=O)O>>COC(=O)c1nc(Br)cnc1N,,COCCOC,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20090247766A1,COc1ccc(B(O)O)cc1.Nc1cccc2c1C(=O)CCC2.O=CC(=O)O>>COc1ccc(C(Nc2cccc3c2C(=O)CCC3)C(=O)O)cc1,,CC#N,,O,,test
US04772706,CC(C)(C)OC(=O)NC1CCNC1.N#Cc1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O>>CC(C)(C)OC(=O)NC1CCN(c2c(F)cc3c(=O)c(C#N)cn(C4CC4)c3c2F)C1,,CC#N,,CCN(CC)CC,,test
US20120298966A1,Brc1ccc2[nH]c3ccccc3c2c1.CC(=O)OC(C)=O>>CC(=O)n1c2ccccc2c2cc(Br)ccc21,O=S(=O)(O)O,ClC(Cl)Cl,,,,test
US05710293,CO.O=C(O)c1ccccc1>>COC(=O)c1ccccc1,,O,,,,test
US20070249587A1,CC(C)(C)OC(=O)N1CCC(C(CO)CO)CC1.Cl>>Cl.OCC(CO)C1CCNCC1,,CO,,C1COCCO1,,test
US05344932,CCOC(=O)CC[C@H](NC(=O)c1ccc(C(CO)Cn2cnc3nc(NC(=O)C(C)(C)C)cc-3c2O)cc1)C(=O)OCC>>Nc1cc2c(O)n(CC(CO)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)cnc-2n1,,[Na+],[OH-],Cl,,test
US04666907,BrBr.COc1ccc2nc3cc(OC)c(=O)cc-3sc2c1>>COc1ccc2nc3cc(OC)c(=O)c(Br)c-3sc2c1,,CC(=O)O,,CO,,test
US20050032829A1,CCCc1nc2c(c(C)c(C)n3nnnc23)n1CC(C)(C)N.O=C(Cl)c1ccccc1>>CCCc1nc2c(c(C)c(C)n3nnnc23)n1CC(C)(C)NC(=O)c1ccccc1,,O,,CCN(CC)CC,ClCCl,test
US20040087659A1,Nc1ccc(C(=O)O)cc1N.O=C=NC(=O)c1ccc(F)cc1Cl>>Nc1ccc(C(=O)O)cc1NC(=O)NC(=O)c1ccc(F)cc1Cl,,CN1CCCC1=O,,ClCCl,,test
US20100152450A1,CC(C)(C)OC(=O)N1CC[C@H]1COc1cncc(CCc2cccc(CO)c2)c1.ClCCl>>Cl.OCc1cccc(CCc2cncc(OC[C@@H]3CCN3)c2)c1,,O,O=C(O)C(F)(F)F,,,test
US20100137299A1,ClCI.O=C1C(c2cc3c(cc2O)OCCO3)c2cc(Br)ccc2N1Cc1ccccn1>>O=C1N(Cc2ccccn2)c2ccc(Br)cc2C12COc1cc3c(cc12)OCCO3,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20130317023A1,Cc1c(Cl)cccc1S(=O)(=O)Cl.Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F>>Cc1c(Cl)cccc1S(=O)(=O)Nc1ccc(F)c(Nc2ncccc2-c2ncnc3c2ncn3C2CCCCO2)c1F,,ClCCl,,c1ccncc1,,test
US20160115128A1,BrCc1ccccc1.CCOC(=O)CNc1ccccc1>>CCOC(=O)CN(Cc1ccccc1)c1ccccc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130035318A1,C=C(C)[C@@H]1CC[C@]2(NCC3CCCN(C(=O)OC(C)(C)C)C3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NCC3CCCN(C(=O)OC(C)(C)C)C3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1COCCO1,CO,[Na+].[OH-],,test
US20130289027A1,Cc1ccc(F)c2c1CCCO2.O=C1OC(=O)c2ccccc21>>Cc1c(C(=O)c2ccccc2C(=O)O)cc(F)c2c1CCCO2,,ClCCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
USRE039591E1,[N-]=[N+]=NCc1ccc2ncccc2c1>>NCc1ccc2ncccc2c1,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06136823,CN.Nc1cc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(Cl)c32)c(Br)cc1F>>CNc1c(F)cc2c(=O)c(C(=O)O)cn(-c3cc(N)c(F)cc3Br)c2c1Cl,,c1ccncc1,,,,test
US04902698,Nc1ccc(CCCC(=O)O)nc1.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=C(O)CCCc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cn1,,c1ccncc1,,,,test
US05210239,CI.COCOc1cc(OC)c(OC)c(OC)c1O>>COCOc1cc(OC)c(OC)c(OC)c1OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030008867A1,O=C(N[C@H]1CN2CCC1CC2)c1ccc(Br)s1.O=C([O-])[O-].c1ccncc1>>O=C(N[C@H]1CN2CCC1CC2)c1ccc(Oc2ccccc2)s1,I[Cu]I,c1ccncc1,,O,,test
US20090192176A1,N#Cc1cnn(CC(F)(F)F)c1NC(=O)c1ccc([N+](=O)[O-])cc1.OO>>O=[N+]([O-])c1ccc(-c2nc(O)c3cnn(CC(F)(F)F)c3n2)cc1,,CCO,,[Na+].[OH-],,test
US20100029611A1,C=CC(=O)OCC.c1ccc(C2(c3ccc4nc(-c5ccc6[nH]ccc6c5)sc4n3)CC2)cc1>>CCOC(=O)CCn1ccc2cc(-c3nc4ccc(C5(c6ccccc6)CC5)nc4s3)ccc21,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130261103A1,CN1CCn2nc(Nc3cc(Cl)n[nH]c3=O)cc2C1.Cc1c(B2OC(C)(C)C(C)(C)O2)cccc1N1Cc2cc(C(C)(C)C)sc2C1=O>>Cc1c(-c2cc(Nc3cc4n(n3)CCN(C)C4)c(=O)[nH]n2)cccc1N1Cc2cc(C(C)(C)C)sc2C1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20150087658A1,O=Cc1c(Cl)ncnc1Cl.O=S(=O)(Cl)Cl>>O=C(Cl)c1c(Cl)ncnc1Cl,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20090093454A1,C[C@H]1CCCN1.Fc1cccc2nc(CN3CCC[C@H]4CCc5cccnc5[C@H]43)cn12>>C[C@H]1CCCN1c1cccc2nc(CN3CCC[C@H]4CCc5cccnc5[C@H]43)cn12,,CCO,,,,test
US20020137782A1,CCOC(=O)CC(=CCCOCc1ccccc1)c1ccc(NC(=O)Cc2ccc3nc(Nc4ccccc4C)oc3c2)cc1>>CCOC(=O)CC(CCCO)c1ccc(NC(=O)Cc2ccc3nc(Nc4ccccc4C)oc3c2)cc1,[Pd],CCO,,[H][H],,test
US20160159773A1,CNC(C)(C)CO.O=C(O)c1ccc(Br)nc1>>CN(C(=O)c1ccc(Br)nc1)C(C)(C)CO,,CCOC(C)=O,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20160221994A1,OCC1Cc2cc(Br)cc(Cl)c2O1>>O=CC1Cc2cc(Br)cc(Cl)c2O1,,ClCCl,,O,,test
US20140031360A1,C=C(c1ccc2c(c1)c(-c1cncc(O[C@H]3CN(C(=O)OC(C)(C)C)CCC34CC4)n1)nn2C1CCCCO1)C(F)(F)F>>CC(c1ccc2c(c1)c(-c1cncc(O[C@H]3CN(C(=O)OC(C)(C)C)CCC34CC4)n1)nn2C1CCCCO1)C(F)(F)F,[Pd],C1CCOC1,,,,test
US20090029905A1,COC[C@H](C)Oc1cc(O)cc(C(=O)Nc2cnc(C)cn2)c1.O=C(c1ccc(Br)cn1)N1CCC1>>COC[C@H](C)Oc1cc(Oc2ccc(C(=O)N3CCC3)nc2)cc(C(=O)Nc2cnc(C)cn2)c1,,CC(=O)N(C)C,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05145958,Nc1c(Cl)cc(C(=O)Oc2ccccc2)cc1Cl>>Nc1c(Cl)cccc1Cl,,O,,,,test
US20060046980A1,COC(=O)c1cc(Cl)c(Oc2ccc(OC)cc2)c(Cl)c1>>O=C(O)c1cc(Cl)c(Oc2ccc(O)cc2)c(Cl)c1,,ClCCl,,BrB(Br)Br,,test
US20020161014A1,Nc1ccc(Br)cc1C(=O)Nc1ccccc1Cl.O=C(Cl)CCl>>O=c1c2cc(Br)ccc2nc(CCl)n1-c1ccccc1Cl,,CC(=O)O,,,,test
US20080287479A1,CNC(=O)c1cc2[nH]c(=O)n(C3CCN(C(=O)OC(C)(C)C)CC3)c2cc1F.O=C(O)C(F)(F)F>>CNC(=O)c1cc2[nH]c(=O)n(C3CC[NH2+]CC3)c2cc1F.O=C([O-])C(F)(F)F,,ClCCl,,,,test
US20110230467A1,CC1CN(Cc2ccccc2)CCC1=O.COc1ccc(CN)c(OC)c1>>COc1ccc(CNC2CCN(Cc3ccccc3)CC2C)c(OC)c1,,CC(Cl)Cl,,[Na+].[OH-],,test
US20150111887A1,BrCCBr.CC(Br)c1ccccc1.[Zn]>>CC([Zn+])c1ccccc1.[Br-],,C1CCOC1,,C[Si](C)(C)Cl,,test
US20070191340A1,Brc1ccc(CN2CCOC(Cc3ccccc3)C2)cc1.OB(O)c1ccccc1C(F)(F)F>>FC(F)(F)c1ccccc1-c1ccc(CN2CCOC(Cc3ccccc3)C2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20020068687A1,Cc1ccc(N)c(C(=O)O)c1.NC=O>>Cc1ccc2nc[nH]c(=O)c2c1,,O,,,,test
US20030203128A1,CC(=O)OC(C)=O.CC(=O)c1ccc2c(c1)Cc1ccccc1-2.OO>>CC(=O)Oc1ccc2c(c1)Cc1ccccc1-2,,O,O=CO,O=S(=O)(O)O,,test
US20090318690A1,CN(C)Cc1c(OCC2CC2)ccc2c(CCC3CCNCC3)noc12.O=Cc1ccc2[nH]ccc2c1>>CN(C)Cc1c(OCC2CC2)ccc2c(CCC3CCN(Cc4ccc5[nH]ccc5c4)CC3)noc12,,C1CCOC1,CCOC(C)=O,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130225554A1,CC(C)C(=O)NNC(=O)[C@H]1CC[C@H]2CN1C(=O)N2OCc1ccccc1>>CC(C)C(=O)NNC(=O)[C@H]1CC[C@H]2CN1C(=O)N2O,[Pd],CO,,[H][H],,test
US20150376179A1,CC(C)(C)OC(=O)N1CCC(n2nccc2CO)CC1.CI>>COCc1ccnn1C1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,[H-].[Na+],,test
US20100286266A1,CI.O=S(=O)(Nc1cccc(CO)c1)c1ccc(-c2ccc(Cl)cc2Cl)cc1>>CN(c1cccc(CO)c1)S(=O)(=O)c1ccc(-c2ccc(Cl)cc2Cl)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160108040A1,C1COCCO1.CC(C)(C)c1cc(NC(=O)OCC(Cl)(Cl)Cl)n(-c2cnn(CCO)c2)n1.CN1CCC[C@H]1c1nnc2ccc(O[C@@H]3CC[C@H](N)c4ccccc43)cn12>>CN1CCC[C@H]1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4cnn(CCO)c4)c4ccccc43)cn12.O=CO,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20140329804A1,COc1ccc(CNc2c(C(=O)NCCN)c(Cl)nc3ccc(C#N)cc23)cc1Cl>>COc1ccc(CNc2c3c(nc4ccc(C#N)cc24)NCCNC3=O)cc1Cl,,CN1CCCC1=O,,CO,,test
US05300524,C#CCC(O)Cc1cccnc1>>OCCCCCc1cccnc1,[Pd],CCOC(C)=O,,CO,[H][H],test
US20050101644A1,NO.O=C1CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1>>ON=C1CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1,,ClCCl,,Cl,c1ccncc1,test
US04035422,Cc1ccc([N+](=O)[O-])c(C)c1O>>Cc1ccc(N)c(C)c1O,[Fe],CC(=O)O,,O,O=C([O-])[O-].[Na+].[Na+],test
US20140243302A1,COc1ccc2ncc(F)c(CCC34CCC(NC(=O)OC(C)(C)C)(CC3)CO4)c2n1.Cl>>Cl.NC12CCC(CCc3c(F)cnc4ccc(O)nc34)(CC1)OC2,,C1COCCO1,,,,test
US20080132505A1,COc1cc(N)ccc1Cl.O=C(NCC1CCCCC1)c1cnc(Cl)nc1C(F)(F)F>>COc1cc(Nc2ncc(C(=O)NCC3CCCCC3)c(C(F)(F)F)n2)ccc1Cl,,C1COCCO1,,,,test
US04975460,CC(=O)NC1Cc2ccc(OC(=O)CCl)cc2C1>>CC(=O)NC1Cc2ccc(O)cc2C1,,CO,,[Na+].[OH-],,test
US20060217372A1,CN(C)C=O.Cc1cc(C=O)ccc1O.NC(=O)c1ccc(Cl)nc1.O>>Cc1cc(C=O)ccc1Oc1ccc(C(N)=O)cn1.[NH4+].[OH-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050272721A1,C[C@H](O)C(=O)O.Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1>>CC(O)C(=O)[O-].Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1,,CC(C)=O,,,,test
US20040138269A1,CCOC(=O)c1[nH]c(C)c(-c2ccc(C(=O)O)cc2)c1C.Nc1ccc(C(F)(F)F)cc1>>CCOC(=O)c1[nH]c(C)c(-c2ccc(C(=O)Nc3ccc(C(F)(F)F)cc3)cc2)c1C,CN(C)C=O,CCOC(C)=O,ClCCl,O=C(Cl)C(=O)Cl,,test
US20130274253A1,CC(C)C1Cc2ccccc2N1C(=O)[C@@H](C)OCc1ccccc1>>CC(C)C1Cc2ccccc2N1,,CCO,,Cl,,test
US20010027196A1,CCCCN.CS(=O)(=O)c1nc(N)nc(-c2ccco2)c1C#N>>CCCCNc1nc(N)nc(-c2ccco2)c1C#N,,COCCOC,,,,test
US20150291596A1,COc1cccc(OC)n1.O=C1CCC(=O)N1Br>>COc1ccc(Br)c(OC)n1,,CC#N,,,,test
US20030207877A1,C=C(O[Si](C(C)C)(C(C)C)C(C)C)c1ccccn1.O=C1CCC(=O)N1Cl>>CC(C)[Si](OC(=CCl)c1ccccn1)(C(C)C)C(C)C,,C1CCOC1,,CCOCC,,test
US20040102360A1,Nc1ccc(C(=O)C(=O)c2ccc(N)cc2)cc1.Nc1ccccc1N>>Nc1ccc(-c2nc3ccccc3nc2-c2ccc(N)cc2)cc1,,CC(=O)O,,,,test
US06211183B1,CCOC(=O)CNCC(=O)OCC.NCCc1ccncc1.O=C(O)CBr>>CCOC(=O)CN1CC(=O)N(CCc2ccncc2)CC1=O,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20070191468A1,O=S(=O)(O)O.OCCC#Cc1ccc(C2CC2)cc1>>O=C(CCCO)c1ccc(C2CC2)cc1,,CO,,,,test
US20110070161A1,CCNCC.COc1cccc2c1c1c(n2CCF)CCCC1C(=O)Cl>>CCN(CC)C(=O)C1CCCc2c1c1c(OC)cccc1n2CCF,,ClCCl,,,,test
US20100137302A1,COC(=O)CC(=O)OC.Cc1nc(Cl)cc(Cl)n1>>COC(=O)C(C(=O)OC)c1cc(Cl)nc(C)n1,,C1CCOC1,,[H-].[Na+],,test
US04997967,CC(C)c1cc(Oc2ccccc2)cc(C(C)C)c1NC(N)=S>>CC(C)c1cc(Oc2ccccc2)cc(C(C)C)c1N=C=S,,Cc1ccccc1C,,,,test
US20090163471A1,CC(C)(C)OC(=O)c1ccc(C(N)=O)c([N+](=O)[O-])c1>>CC(C)(C)OC(=O)c1ccc(C(N)=O)c(N)c1,[Pd],CCOC(C)=O,,,,test
US04009187,COC(=O)CCCCCCCc1ccc(COC(C)=O)o1>>COC(=O)CCCCCCCc1ccc(CO)o1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20060241115A1,COc1cc2nccc(Sc3ccccc3)c2cc1OC.O=C(OO)c1cccc(Cl)c1>>COc1cc2nccc(S(=O)c3ccccc3)c2cc1OC,,ClCCl,,O=C([O-])O.[Na+],,test
US20110183997A1,CC1(C(=O)O)CC1.Cc1cc2c(cn1)cc(-c1cc(N/C(N)=N/O)ccc1C)c(=O)n2C>>Cc1cc2c(cn1)cc(-c1cc(Nc3noc(C4(C)CC4)n3)ccc1C)c(=O)n2C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060116410A1,COCCNC(=O)c1cccc(CNc2cc(C#N)ccc2CNC(=O)c2cccc(Cl)c2)c1.NO>>COCCNC(=O)c1cccc(CNc2cc(C(N)=NO)ccc2CNC(=O)c2cccc(Cl)c2)c1,,CCN(CC)CC,,Cl,,test
US20070049595A1,COc1ccc(-c2cc(=O)n(CC=Cc3ccc(Cl)cc3)nc2-c2ccc(OC)cc2)cc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COc1ccc(-c2cc(=S)n(CC=Cc3ccc(Cl)cc3)nc2-c2ccc(OC)cc2)cc1,,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US20100274029A1,CCCCCCCCCCC[C@@H](O)CC#N.C[Si](C)(C)Cl>>CCCCCCCCCCC[C@H](CC#N)O[Si](C)(C)C,,O,,CCN(CC)CC,ClCCl,test
US20010020089A1,CCNC(=O)[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(C(=O)OC)nc32)[C@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1>>CCNC(=O)[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(C(=O)OC)nc32)[C@H](O)[C@@H]1O,,CO,,O=C([O-])[O-].[Na+].[Na+],,test
US04402960,Ic1cccs1.Sc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)[nH]1>>Clc1ccc(-c2nc(Sc3cccs3)[nH]c2-c2ccc(Cl)cc2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20050197331A1,O=[N+]([O-])O.c1ccc(-c2nc3ccccc3s2)cc1>>O=[N+]([O-])c1ccc2nc(-c3ccccc3)sc2c1,,O,,,,test
US20100056469A1,Cc1cc(C)cc(CC(N)c2cccc(C)c2C)c1.S=C(Cl)Cl>>Cc1cc(C)cc(CC(N=C=S)c2cccc(C)c2C)c1,,ClC(Cl)Cl,O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20060142336A1,Br.C=C(C(=O)O)C1CCCC1>>O=C(O)C(CBr)C1CCCC1,,O,,,,test
US20150005279A1,CNC.Cc1c(NC(=O)/C=C/CBr)cccc1-c1ccc(C(N)=O)c2[nH]ccc12>>Cc1c(NC(=O)/C=C/CN(C)C)cccc1-c1ccc(C(N)=O)c2[nH]ccc12,,C1CCOC1,CC(=O)N(C)C,O,,test
US20030105139A1,O=C(Nc1cccnc1)c1cccc([N+](=O)[O-])c1>>Nc1cccc(C(=O)Nc2cccnc2)c1,[Pd],CCO,,,,test
US05344843,COC(=O)C(=O)c1ccc(O)cc1.ClCc1cc2ccccc2o1>>O=C(O)C(=O)c1ccc(OCc2cc3ccccc3o2)cc1,,CN(C)C=O,O,[H-].[Na+],,test
US20070142414A1,CC(C)(C)OC(=O)N1CCc2[nH]c(-c3ccncc3)cc2C1=O.COCCO>>COCCn1c(-c2ccncc2)cc2c1CCN(C(=O)OC(C)(C)C)C2=O,,C1CCOC1,CN(C)C=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130072523A1,C[Si](C)(C)C#Cc1ccc2cc(C#C[Si](C)(C)C)ccc2c1>>C#Cc1ccc2cc(C#C)ccc2c1,,CO,,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20100216795A1,CNC.COc1ccc(Nc2nc(C(N)=O)c(NC(=O)c3ccc(NC(=O)CBr)cc3)s2)cc1>>COc1ccc(Nc2nc(C(N)=O)c(NC(=O)c3ccc(NC(=O)CN(C)C)cc3)s2)cc1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20150166549A1,CC(c1oc(=O)c2ccccc2c1-c1ccccc1)n1nc(-c2cc(F)cc(O[Si](C)(C)C(C)(C)C)c2)c2c(N)ncnc21>>CC(c1oc(=O)c2ccccc2c1-c1ccccc1)n1nc(-c2cc(O)cc(F)c2)c2c(N)ncnc21,,CCO,Cl,,,test
US20060142337A1,On1nnc2ccccc21>>On1nnc2ccccc21,,O,,,,test
US05719152,CC(C)(C)OC(=O)NCc1ccc(NC(=O)C[C@@H]2CCc3cc(Br)cc4[nH]c(=O)c(=O)n2c34)c(CCCC(=O)O)c1.Cl>>Cl.NCc1ccc(NC(=O)C[C@@H]2CCc3cc(Br)cc4[nH]c(=O)c(=O)n2c34)c(CCCC(=O)O)c1,,C1COCCO1,,,,test
US20060004082A1,Cc1cc(C(C)(C)C(=O)OCc2ccccc2)sc1Br>>Cc1cc(C(C)(C)C(=O)O)sc1Br,,CO,O,[Na+].[OH-],,test
US20120077806A1,CCC(=O)c1ccc(O)cc1.CN(C)C=O.COCBr>>CCC(=O)c1ccc(OCCOC)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US05571810,CS(=O)(=O)Cl.CS(=O)(=O)c1ccc(-c2cc(N)sc2-c2ccc(F)cc2)cc1>>CS(=O)(=O)Nc1cc(-c2ccc(S(C)(=O)=O)cc2)c(-c2ccc(F)cc2)s1,,c1ccncc1,,,,test
US20160244437A1,Cc1ccc(S(=O)(=O)N2CCCC2)cc1-c1cccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)c1.Cl>>Cc1ccc(S(=O)(=O)N2CCCC2)cc1-c1cccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3nnn[nH]3)cc2)c1.Cl,,C1COCCO1,,CC#N,,test
US20150065519A1,O=S(=O)(Nc1ccc(-c2csc(Br)n2)c(Cl)c1)C(F)(F)F.OB(O)c1ccc2c(c1)CCO2>>O=S(=O)(Nc1ccc(-c2csc(-c3ccc4c(c3)CCO4)n2)c(Cl)c1)C(F)(F)F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080009488A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccccc1C(=O)c1ccc(N)c(N)c1>>COC(=O)c1ccccc1C(=O)c1ccc(N)c(NC(=O)OC(C)(C)C)c1,,CN(C)C=O,,,,test
US20140356322A1,Cc1ncsc1-c1ccc(CNC(=O)OCC[Si](C)(C)C)cc1>>Cc1ncsc1-c1ccc(CN)cc1,,CC#N,,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20080319188A1,CN1CCC(N2CCNCC2)CC1.O=C(Oc1ccccc1)N(C(=O)Oc1ccccc1)c1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ccn1>>CN1CCC(N2CCN(C(=O)Nc3cc(Oc4ccc(NC(=O)C5(C(=O)Nc6ccc(F)cc6)CC5)cc4F)ccn3)CC2)CC1,,CN(C)C=O,,,,test
US20050009808A1,CCOC(=O)[C@H]1N[C@@H]2CC[C@H]1C2.COc1ccc(S(=O)(=O)Cl)cc1>>CCOC(=O)[C@@H]1[C@H]2CC[C@H](C2)N1S(=O)(=O)c1ccc(OC)cc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20100311972A1,CN1CCN(C2CCN(C(=O)Nc3cc(Oc4ccc(NC(=O)OC(C)(C)C)c(F)c4)ccn3)CC2)CC1>>CN1CCN(C2CCN(C(=O)Nc3cc(Oc4ccc(N)c(F)c4)ccn3)CC2)CC1,,CCOC(C)=O,,Cl,[Na+].[OH-],test
US20040048882A1,Cn1cncc1C(O)(c1ccc2c(c1)c(-c1cccc(Cl)c1)cc(=O)n2C)c1ccccc1C=O>>Cn1cncc1C(O)(c1ccc(CO)cc1)c1ccc2c(c1)c(-c1cccc(Cl)c1)cc(=O)n2C,,C1CCOC1,,O,[BH4-].[Na+],test
US05070215,C=COC(=O)Cl.OCCBr>>C=COC(=O)OCCBr,,CCOCC,,c1ccncc1,,test
US04101667,N#Cc1cccc2c1CC(=O)c1cc(F)ccc1S2.NN>>N#Cc1cccc2c1CC(=NN)c1cc(F)ccc1S2,,CCO,,O,,test
US20090137581A1,Cc1nc2cccc(Cl)c2nc1Cl.OB(O)c1cccc(F)c1>>Cc1nc2cccc(Cl)c2nc1-c1cccc(F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,O,O=C(O)O,,test
US05852018,CC(=O)N1CC(=O)NC(=Cc2ccccc2)C1=O.CI>>CC(=O)N1CC(=O)N(C)C(=Cc2ccccc2)C1=O,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US03968103,CC(=O)OC[C@H]1O[C@@H](n2cc(C(N)=S)nn2)[C@H](OC(C)=O)[C@@H]1OC(C)=O>>NC(=S)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)nn1,,CO,,C[O-].[Na+],,test
US06022718,CCCCCCCC/C=C\CCCCCCCC(=O)O.COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O>>CCCCCCCC/C=C\CCCCCCCC(=O)NCc1ccc(O)c(OC)c1,,CCCCCC,,O,,test
US20030149027A1,COC(=O)CN1C(=O)C(CC(=O)O)C(=O)N(c2ccc(CNC(=O)OC(C)(C)C)cc2)c2ccccc21.NCc1ccccc1F>>COC(=O)CN1C(=O)C(CC(=O)NCc2ccccc2F)C(=O)N(c2ccc(CNC(=O)OC(C)(C)C)cc2)c2ccccc21,,CN(C)C=O,O,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20130116216A1,O=C(OCc1ccccc1)N1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CC1>>Nc1ccc(S(=O)(=O)N2CCN(C(=O)OCc3ccccc3)CC2)cc1,[Fe],O,,CCO,[Cl-].[NH4+],test
US04895872,CC(=O)CC(=O)OC(C)(C)C.N#CCCC(=O)Cl>>CC(=O)CC(=O)CCC#N,,CCOCC,,,,test
US06313116B1,CCc1nc2c(OC)ccc(C(=O)O)c2s1.Cn1ncc(C#N)c1N>>CCc1nc2c(OC)ccc(C(=O)Nc3c(C#N)cnn3C)c2s1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US06479512B1,CC(C)(C)OC(=O)Nc1cccnc1.CN(C)C=O>>CC(C)(C)OC(=O)Nc1cnccc1C=O,,C1CCOC1,,[Li]C(C)(C)C,,test
US20050080074A1,COCc1cc2c(c(C(F)(F)F)c1)C(=O)N1CCN(C(=O)OC(C)(C)C)C[C@@H]21.Cl>>COCc1cc2c(c(C(F)(F)F)c1)C(=O)N1CCNC[C@@H]21.Cl,,CCOCC,O,,,test
US20030158188A1,C1CCC2=NCCCN2CC1.CCOC(C)=O.NCCc1cccc(F)c1>>O=C(NCCc1cccc(F)c1)Nc1cccc2cnccc12,,CC#N,,,,test
US20150353581A1,CC(N)(C#N)COc1ccc2c(c1C#N)B(O)OC2.O=C(O)c1ccc(OC(F)(F)F)cc1>>CC(C#N)(COc1ccc2c(c1C#N)B(O)OC2)NC(=O)c1ccc(OC(F)(F)F)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100210620A1,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.CCOCC.O=C(n1ccnc1)n1ccnc1>>CON(C)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1,,CCOCC,,C1CCOC1,CCN(CC)CC,test
US04613606,CCOC(CCCl)OCC.COc1ccc(CC#N)cc1OC>>CCOC(CCC(C#N)c1ccc(OC)c(OC)c1)OCC,,CN(C)C=O,,[H-].[Na+],,test
US20160244451A1,CCc1ncc(-c2ccc(S(=O)(=O)Nc3c(F)c(F)c(C(=O)OC)c(F)c3F)cc2)cn1>>CCc1ncc(-c2ccc(S(=O)(=O)Nc3c(F)c(F)c(C(=O)O)c(F)c3F)cc2)cn1,,CO,,Cl,[Li+].[OH-],test
US06300352B1,CCOC(=O)[C@@H](C)O.Oc1ccc(Br)cc1>>CCOC(=O)[C@H](C)Oc1ccc(Br)cc1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06670387B1,Oc1ccc2ccccc2c1.[N-]=[N+]=C1c2ccccc2C(S(=O)(=O)O)=CC1O>>O=S(=O)(O)c1cc(O)c(N=Nc2c(O)ccc3ccccc23)c2ccccc12,,O,,Cl,O=C([O-])O.[Na+],test
US05149700,CC(=O)NCCNc1ccc2ccccc2n1>>NCCNc1ccc2ccccc2n1,,Cl,,,,test
US20150182507A1,COC(=O)c1ccccc1O.ClCc1nc2ccccn2c1I>>COC(=O)c1ccccc1OCc1nc2ccccn2c1I,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US04647558,CC(=O)OO.CCN1CCN(C(=O)NC(C(=O)NC2(SC)C(=O)NC2C)c2ccccc2)C(=O)C1=O>>CCN1CCN(C(=O)NC(C(=O)NC2(S(C)=O)C(=O)NC2C)c2ccccc2)C(=O)C1=O,,C1COCCO1,CC(=O)O,,,test
US20090239810A1,O=C(NCC(=O)N1CCC(Oc2ccccc2Cl)CC1)c1cc(-c2ccccc2OCc2ccccc2)[nH]n1>>O=C(NCC(=O)N1CCC(Oc2ccccc2Cl)CC1)c1cc(-c2ccccc2O)[nH]n1,[Pd],CO,,,,test
US20160272596A1,COc1ccc2cc(Br)ccc2c1CN1C(=O)[C@@H](NC(=O)OC(C)(C)C)CN(C(=O)c2ccc(C(C)=O)cc2)c2ccccc21.Cl>>COc1ccc2cc(Br)ccc2c1CN1C(=O)[C@@H](N)CN(C(=O)c2ccc(C(C)=O)cc2)c2ccccc21.Cl,,C1COCCO1,,CCOCC,,test
US20110183998A1,CC(=O)NC(C)CCc1ccc(O)cc1.CC(C)Oc1ccc(Cl)nn1>>CC(=O)NC(C)CCc1ccc(Oc2ccc(OC(C)C)nn2)cc1,,CN1CCCC1=O,O,CCOC(C)=O,[H-].[Na+],test
US20150336949A1,CC(C)(C)OC(=O)N1CCC(Nc2cccc(-c3cnc4[nH]cc(-c5cnn(CCc6ccccc6)c5)c4c3)c2)CC1>>c1ccc(CCn2cc(-c3c[nH]c4ncc(-c5cccc(NC6CCNCC6)c5)cc34)cn2)cc1,,CO,Cl,,,test
US05024847,CC(C)OC(=O)N=NC(=O)OC(C)C.CC(O)=S.CC=C(CO)CCC=C(C)C>>CC(=O)O.CC=C(CS)CCC=C(C)C,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140213554A1,Nc1ncc([N+](=O)[O-])cc1C#Cc1ccc(F)cc1>>Nc1cnc(N)c(C#Cc2ccc(F)cc2)c1,,C1CCOC1,CCOC(C)=O,Cl[Sn]Cl,,test
US20130225552A1,Clc1nccnc1Cl.N[C@H]1C[C@H](Nc2nc3ccccc3s2)C1>>Clc1nccnc1N[C@@H]1C[C@@H](Nc2nc3ccccc3s2)C1,,CC(C)O,,,,test
US20130225554A1,COCC(=O)NNC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1>>COCC(=O)NNC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2O,[Pd],CO,,,,test
US20150057260A1,CCOC(=O)C(=O)OCC.Cc1cccnc1C(=O)NC(C)(C)C>>CCOC(=O)C(=O)Cc1cccnc1C(=O)NC(C)(C)C,,C1CCOC1,CCCCCC,CN(C)CCN(C)C,[Li]CCCC,test
US20120283271A1,CC(C)(C)OC(=O)Cn1ccc(NC(=O)[C@H](CC2CCCC2)N2Cc3c(cccc3C(F)(F)F)C2=O)n1>>O=C(O)Cn1ccc(NC(=O)[C@H](CC2CCCC2)N2Cc3c(cccc3C(F)(F)F)C2=O)n1,,C1CCOC1,O,[Li+].[OH-],,test
US20060281789A1,O=Cc1ccc(N2CCOCC2)c([N+](=O)[O-])c1.c1ccc([P+](Cc2n[nH]c3ccccc23)(c2ccccc2)c2ccccc2)cc1>>O=[N+]([O-])c1cc(/C=C/c2n[nH]c3ccccc23)ccc1N1CCOCC1,,CO,,[I-].[K+],,test
US05480902,O=[N+]([O-])O.O=[N+]([O-])c1ccc(-c2cc(-c3ccc(Cl)cc3)[nH]c2C(F)(F)F)s1>>O=[N+]([O-])c1ccc(-c2c(C(F)(F)F)[nH]c(-c3ccc(Cl)cc3)c2[N+](=O)[O-])s1,,CC(=O)OC(C)=O,,O,,test
US20160244429A1,Cc1ccc(S(=O)(=O)OCCCc2c[nH]c3ccc(C#N)cc23)cc1.O=C1CCCCN1c1ccc(N2CCNCC2)cc1>>N#Cc1ccc2[nH]cc(CCCN3CCN(c4ccc(N5CCCCC5=O)cc4)CC3)c2c1,,CC#N,,[I-].[K+],,test
US05635527,CO.Nc1ccc(C=CC(=O)O)cc1>>COC(=O)C=Cc1ccc(N)cc1,,ClC(Cl)Cl,,O=S(=O)(O)O,,test
US20130245042A1,NC(=O)C1(c2ccc(F)cc2)CC1>>NCC1(c2ccc(F)cc2)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130231328A1,CN(C(=O)OC(C)(C)C)C1CCC(Oc2ncnc3sc4c(c23)[C@@H](CC(N)C#N)CC4)CC1.O=C(Cl)OCc1ccccc1>>CN(C(=O)OC(C)(C)C)C1CCC(Oc2ncnc3sc4c(c23)[C@@H](CC(C#N)NC(=O)OCc2ccccc2)CC4)CC1,,ClCCl,ClCCl,CCN(CC)CC,,test
US20090076004A1,CCOC(=O)Cc1c(C(=O)OCC)c2cc(Oc3nc(C)ccc3C#N)ccc2n1-c1ccc(OC(C)C)cc1>>CCOC(=O)c1c(CC(=O)O)n(-c2ccc(OC(C)C)cc2)c2ccc(Oc3nc(C)ccc3C#N)cc12,,CCO,,[Na+].[OH-],,test
US20040186140A1,C=CCC(CCc1cccc(C(F)(F)F)c1)C(=O)OCC.O=[O+][O-]>>CCOC(=O)C(CCc1cccc(C(F)(F)F)c1)CC1COOO1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060205713A1,O=C(c1ccccc1C(F)(F)F)N1CCN(c2ccc(Cl)nn2)CC1.SCCc1ccccc1>>O=C(c1ccccc1C(F)(F)F)N1CCN(c2ccc(SCCc3ccccc3)nn2)CC1,,C1COCCO1,O,[Na+].[OH-],,test
US05344843,COC(=O)C(=O)c1ccc(OCc2ccc3ccccc3c2)cc1>>O=C(O)C(=O)c1ccc(OCc2ccc3ccccc3c2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20150274740A1,CCOC(=O)CC(=O)c1ccc2[nH]nnc2c1.CNC(=O)c1n[nH]c(N)n1>>CNC(=O)c1nc2[nH]c(-c3ccc4[nH]nnc4c3)cc(=O)n2n1,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US03954728,CCO.CN(N=O)C1=Nc2ccc(Cl)cc2C(c2ccccc2)=[N+]([O-])C1>>CC(=O)NNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=[N+]([O-])C1,,CCN(CC)CC,,,,test
US20020133015A1,COCCC1(C(=O)N[C@@H](Cc2ccc(-c3cc(Cl)cn(C)c3=O)cc2)C(=O)OC)CCCC1>>COCCC1(C(=O)N[C@@H](Cc2ccc(-c3cc(Cl)cn(C)c3=O)cc2)C(=O)O)CCCC1,CC(=O)O,C1CCOC1,O,[Li+].[OH-],,test
US20050245571A1,CC(C)N(C(C)C)C(C)c1c[nH]c2ccccc12.COC(=O)C[N+](=O)[O-]>>COC(=O)C(C(C)c1c[nH]c2ccccc12)[N+](=O)[O-],,Cc1ccccc1,,CCN(CC)CC,CCO,test
US04343809,N#CCCl.Oc1ccc(Cl)cc1>>N#CCOc1ccc(Cl)cc1,,O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20040053924A1,CN1C(=O)Cc2c(Nc3ccc(F)c(Cl)c3)ncnc21.Cc1cc(C)c(C=O)[nH]1>>Cc1cc(C)c(C=C2C(=O)N(C)c3ncnc(Nc4ccc(F)c(Cl)c4)c32)[nH]1,C1CCNCC1,CCO,,,,test
US20130150414A1,CSC(=CC(=O)C(F)(F)F)SC.NCCS>>O=C(C=C1NCCS1)C(F)(F)F,,CCO,,,,test
US04197298,BrBr.CON=C(C(C)=O)C(=O)OC>>CON=C(C(=O)CBr)C(=O)OC,,ClC(Cl)Cl,,,,test
US20030162818A1,NS(=O)(=O)c1ccccc1NC(=O)c1ccccc1OCc1ccccc1.O=C(Cl)c1ccc(F)cc1F>>O=C(Nc1ccccc1S(=O)(=O)NC(=O)c1ccc(F)cc1F)c1cccc(OCc2ccccc2)c1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US06207686B1,COC(=O)C(Cc1ccccc1OCc1ccccc1)C(O)C1CCCCC1>>O=C(O)C(Cc1ccccc1OCc1ccccc1)C(O)C1CCCCC1,,[K+],[OH-],,,test
US04438270,CCC(=O)Cl.COC(=O)C(N)(CCCNC(C)=O)C(F)F>>CCC(=O)NC(CCCNC(C)=O)(C(=O)OC)C(F)F,,CCOCC,,CCN(CC)CC,,test
US20140045862A1,COc1ccc(CNS(=O)(=O)c2ccc(O[C@H]3CCC[C@@H]3c3ccnn3C)c(F)c2)c(OC)c1>>Cn1nccc1[C@H]1CCC[C@@H]1Oc1ccc(S(N)(=O)=O)cc1F,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20120214762A1,CC(C)(C)[SiH2]OC(C)(C)C1(CO)CCCC1>>CC(C)(C)[SiH2]OC(C)(C)C1(C=O)CCCC1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20110183979A1,N#CC(Cl)CCl.NNc1ccncc1>>Nc1ccn(-c2ccncc2)n1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20070135497A1,C#CCBr.CNC(=O)c1cccc(-c2c(Cl)ccc(Cl)c2Cl)c1>>C#CCN(C)C(=O)c1cccc(-c2c(Cl)ccc(Cl)c2Cl)c1,,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US20110288067A1,CS(=O)(=O)Cl.C[C@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(C3CC3)nc12)C(C)(C)CO>>C[C@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(C3CC3)nc12)C(C)(C)COS(C)(=O)=O,,ClCCl,,CCN(C(C)C)C(C)C,[Cl-].[NH4+],test
US20130079313A1,CCOC(=O)CN.COc1ccc(C=O)cc1OC>>CCOC(=O)CNCc1ccc(OC)c(OC)c1,CC(C)O[Ti](OC(C)C)(OC(C)C)OC(C)C,C1CCOC1,O,CCO,[BH4-].[Na+],test
US20060122399A1,CC(=O)Cl.CCc1cc(Br)ccc1CN>>CCc1cc(Br)ccc1CNC(C)=O,,ClCCl,O,CCN(CC)CC,,test
US05356966,CCCCCCCCCCCCCCCCCCO.Cc1ccc(O)c(C)c1.O=C(O)COc1ccc(C(O)C(=O)O)cc1>>CCCCCCCCCCCCCCCCCCOC(=O)COc1ccc(C2C(=O)Oc3c(C)cc(C)cc32)cc1,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,,,test
US04784791,ClCc1ccccc1.O=C(O)c1ccc(O)cc1F>>O=C(O)c1ccc(OCc2ccccc2)cc1F,,CCO,,[K+].[OH-],,test
US20080280875A1,Cn1ccc(NC(=O)c2cc(Oc3ccc(C#N)c(F)c3)c3c(c2)OC(C)(C)C3)n1.[NH4+].[OH-]>>Cn1ccc(NC(=O)c2cc(Oc3ccc(C(=N)NO)c(F)c3)c3c(c2)OC(C)(C)C3)n1,,CCO,O,,,test
US07605144B2,O=C(O)C=CC=Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O.O=C1CCC(=O)N1Br>>O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1/C=C/C=C\Br,,CN(C)C=O,,O=C=O,,test
US06057313,Nc1c([N+](=O)[O-])cc(Br)c2c1CN(Cc1ccccc1)CC2>>Nc1cc(Br)c2c(c1N)CN(Cc1ccccc1)CC2,[Ni],C1CCOC1,,,,test
US20110183978A1,CNN.COC(=O)CC(=O)c1ccc(F)cc1>>CN1N=C(c2ccc(F)cc2)CC1=O,,CCOC(C)=O,,CCOCC,O,test
US20060040918A1,O=C(c1ccc(Cl)nn1)N1CCOCC1.Oc1ccc2c(c1)CCN(C1CCC1)CC2>>O=C(c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nn1)N1CCOCC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05929067,CCOC(=O)C=CC(NC)C(c1ccccc1)c1ccccc1.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CCOC(=O)C=CC(C(c1ccccc1)c1ccccc1)N(C)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US06172228B2,CNC.O=S(=O)(Cl)CCCCCCCl>>CN(C)S(=O)(=O)CCCCCCCl,,CC#N,,CCOCC,,test
US03953436,CON.O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)C(C(=O)Cl)=CS[C@H]12>>CONC(=O)C1=CS[C@@H]2C(NC(=O)Cc3cccs3)C(=O)N2C1C(=O)OC(c1ccccc1)c1ccccc1,,C1CCOC1,,,,test
US20130096118A1,CCOC(=O)C(NCc1c[nH]c2c(C#N)ccc(Br)c12)C(OCC)OCC>>CCOC(=O)c1cc2[nH]c3c(C#N)ccc(Br)c3c2cn1,Cl[Ti](Cl)(Cl)Cl,Cc1ccccc1,,,,test
US20150141433A1,COC(=O)c1c[nH]c(=O)c(C(F)(F)F)n1.O=P(Cl)(Cl)Cl>>COC(=O)c1cnc(Cl)c(C(F)(F)F)n1,,CN(C)C=O,,,,test
US20110301161A1,CC1(C)OB(c2cnc(N)nc2)OC1(C)C.CN(C)C=O.CNC(=O)c1nc(-c2ccccc2-c2nc3cc(Br)ccc3n2C(C)(C)C)no1>>CNC(=O)c1nc(-c2ccc(C)cc2-c2nc3cc(-c4cnc(N)nc4)ccc3n2C(C)(C)C)no1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20090258893A1,O=C([O-])N1CCC2C(c3ccc(F)cc3)Nc3ccccc3C21>>Fc1ccc(C2Nc3ccccc3C3NCCC23)cc1,[Pd],CCO,,,,test
US20160272632A1,CON(C)C(=O)[C@@H]1CC[C@@](CC#N)(n2nc(Nc3ccc(Cl)cc3)c3c(=O)[nH]ccc32)CO1.C[Mg]Br>>CC(=O)[C@@H]1CC[C@@](CC#N)(n2nc(Nc3ccc(Cl)cc3)c3c(=O)[nH]ccc32)CO1,,C1CCOC1,,,,test
US20120214762A1,CC(C)(O)c1nn(-c2ccnc(N)n2)c2cc(Br)ccc12.CCN(CC)S(F)(F)F>>CC(C)(F)c1nn(-c2ccnc(N)n2)c2cc(Br)ccc12,,ClCCl,,O=C([O-])O.[Na+],,test
US20100185022A1,CCOP(=O)(OCC)c1ccc(O)cc1>>O=P(O)(O)c1ccc(O)cc1,,CC#N,,C[Si](C)(C)Br,,test
US20130102778A1,CN(C)C=O.O=C1CCC(=O)N1Cl.ON=C(Cl)c1ccc(F)cc1.ON=Cc1ccc(F)cc1>>CCOC(=O)c1c(-c2ccc(F)cc2)noc1C,,O,,,,test
US20010044539A1,COC(=O)C1CCCCc2noc(=O)n21>>O=c1onc2n1C(CO)CCCC2,,C1CCOC1,,[BH4-].[Li+],,test
US04806549,CCOC(=O)C(=CNc1ccccc1OC)C(=O)C1CCCCC1>>COc1cccc2c(=O)c(C(=O)C3CCCCC3)c[nH]c12,,c1ccc(Oc2ccccc2)cc1,,,,test
US20120010190A1,Cc1cc(C(=O)C[C@H](c2ccc(C3CCNCC3)cc2)c2ccc(Cl)cc2C)ccn1.NS(N)(=O)=O>>Cc1cc(C(=O)C[C@H](c2ccc(C3CCN(S(N)(=O)=O)CC3)cc2)c2ccc(Cl)cc2C)ccn1,,C1COCCO1,,,,test
US20130005728A1,Cl.N#CCc1ccc(OC(F)(F)F)cc1>>Cl.NCCc1ccc(OC(F)(F)F)cc1,[Pd],CO,,[H][H],,test
US20040077867A1,CN(C)CCC1CCc2cc(OCc3ccc(-c4ccccc4)cc3)ccc2C1.O=C(O)CC(O)(CC(=O)O)C(=O)O>>CN(C)CCC1CCc2cc(OCc3ccc(-c4ccccc4)cc3)ccc2C1.O=C(O)CC(O)(CC(=O)O)C(=O)O,,CO,,,,test
US20100069381A1,CN.CS(=O)(=O)c1nnc(-c2ccc3ncn(-c4ccc(OC(F)F)cc4)c3c2)o1>>CNc1nnc(-c2ccc3ncn(-c4ccc(OC(F)F)cc4)c3c2)o1,,CN1CCCC1=O,,C1CCOC1,,test
US20030105099A1,O=C(O)C(COC1CCOCC1)CSCc1ccccc1.O=S([O-])OO>>O=C(O)C(COC1CCOCC1)CS(=O)(=O)Cc1ccccc1,,CO,,O,,test
US04036982,CCOC(=O)COc1ccc(Cl)cc1C(=O)OCC>>CCOC(=O)c1oc2ccc(Cl)cc2c1O,,CCO,,O,,test
US20140045823A1,CCOC(=O)C(N)=NO.N#Cc1ccc(C(=O)Cl)cc1F>>CCOC(=O)c1noc(-c2ccc(C#N)c(F)c2)n1,,CC(=O)O,,CCO,,test
US20140206663A1,C[C@@H]1C(=O)NN=C2COc3cc(-c4ccccc4F)c(N(C)C4(C)CN(C(=O)OC(C)(C)C)C4)cc3N21.Cl>>C[C@@H]1C(=O)NN=C2COc3cc(-c4ccccc4F)c(N(C)C4(C)CNC4)cc3N21.Cl,,CCOC(C)=O,,,,test
US20120252777A1,COc1ccc(Nc2nc(N3CCCC(C(=O)O)C3)nc3scnc23)cc1OC.Nc1cnccn1>>COc1ccc(Nc2nc(N3CCCC(C(=O)Nc4cnccn4)C3)nc3scnc23)cc1OC,,c1ccncc1,,O=P(Cl)(Cl)Cl,O=C([O-])O.[Na+],test
US20090192322A1,CN1CCN(c2ccc(C(=O)NC3(C(=O)N4CC[C@H]5OC[C@H](O)[C@H]54)CCCCC3)cc2)CC1>>NC1(C(=O)N2CC[C@H]3OC[C@H](O)[C@H]32)CCCCC1,[Pd],CO,,[H][H],,test
US20060217372A1,Cc1noc(C)c1CCl.NCCc1ccc(Oc2ccc(C(N)=O)cn2)cc1>>Cc1noc(C)c1CNCCc1ccc(Oc2ccc(C(N)=O)cn2)cc1,,CN(C)C=O,,[Na+].[OH-],,test
US20110312935A1,COC(=O)c1ccc2c(c1)nc(Nc1c(Cl)cccc1Cl)n2C>>Cn1c(Nc2c(Cl)cccc2Cl)nc2cc(C(=O)O)ccc21,,CCO,,[Na+].[OH-],,test
US20090093601A1,CC(C)C(=O)Oc1cccc(C(=O)O)c1.O=S(Cl)Cl>>CC(C)C(=O)Oc1cccc(C(=O)Cl)c1,CN(C)C=O,ClCCl,,,,test
US04150030,CCc1coc(=O)[nH]1.O=C(Cl)c1ccccc1Cl>>CCc1coc(=O)n1C(=O)c1ccccc1Cl,,c1ccccc1,,CCN(CC)CC,,test
US06719520B2,CN(C)C=O.Cc1ccc(NC2=C(c3ccc(I)cc3)C(=O)NC2=O)cc1F>>COCCNC1=C(c2ccc(I)cc2)C(=O)NC1=O,,Cl,,,,test
US20120053173A1,Cc1c(C(=O)C2CCCC2)oc2c(F)cc(F)cc12>>Cc1c(C(O)C2CCCC2)oc2c(F)cc(F)cc12,,C1CCOC1,CO,O,[BH4-].[Na+],test
US20110319392A1,NC(=S)N1CCCC1.O=C(Cc1ccnc(Cl)n1)c1ccc(F)c(NS(=O)(=O)c2c(F)cccc2F)c1>>O=S(=O)(Nc1cc(-c2nc(N3CCCC3)sc2-c2ccnc(Cl)n2)ccc1F)c1c(F)cccc1F,,CCOC(C)=O,ClCCl,O=C1CCC(=O)N1Br,,test
US20070197530A1,CC(C)(C)OC(=O)N1C2CC3CC1CC(C2)O3.Cl>>C1C2CC3CC(CC1O3)N2.Cl,,C1COCCO1,,,,test
US05602117,COc1ccc(COC(=O)C2C(C3CCCS3(=O)=O)=CS[C@@H]3[C@H](NC(=O)Cc4ccccc4)C(=O)N23)cc1.O=C(OO)c1cccc(Cl)c1>>COc1ccc(COC(=O)C2=C(C3CCCS3(=O)=O)CS(=O)[C@@H]3[C@H](NC(=O)Cc4ccccc4)C(=O)N23)cc1,,ClCCl,,,,test
US20100029636A1,CCCCOC(=O)Nc1ccc(-c2cnc3c(-c4cccc(N5CCN(C(=O)OCc6ccccc6)CC5)c4)cnn3c2N)cc1>>CCCCOC(=O)Nc1ccc(-c2cnc3c(-c4cccc(N5CCNCC5)c4)cnn3c2N)cc1,[Pd],CN(C)C=O,,,,test
US20120059030A1,COc1cc(C#CCCCC(C)(O)c2ccc(Cl)c(Cl)c2)ccc1-n1cnc(C)n1.C[Si](C)(C)N=[N+]=[N-]>>COc1cc(-c2nnn3c2CCCC3(C)c2ccc(Cl)c(Cl)c2)ccc1-n1cnc(C)n1,,CCOC(C)=O,,Cc1ccccc1,,test
US20100035898A1,COC(=O)c1ccc(NC[C@@H]2CC[C@@H](NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)nc1>>O=C(O)c1ccc(NC[C@@H]2CC[C@@H](NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)nc1,,CO,,[Na+].[OH-],,test
US20040034221A1,COC(=O)c1ncc2cccnc2c1O.NCc1ccccn1>>O=C(NCc1ccccn1)c1ncc2cccnc2c1O,,Cc1ccccc1,,,,test
US20060084643A1,Cc1ccc(Nc2ccc(F)cc2[N+](=O)[O-])c(C#N)c1.Cl>>Cc1ccc2c(c1)C(N)=Nc1cc(F)ccc1N2.Cl,,CCO,Cl,Cl[Sn]Cl,,test
US04948794,CNc1ccc(C(F)(F)F)cc1[N+](=O)[O-]>>CNc1ccc(C(F)(F)F)cc1N,[Pd],CCO,,,,test
US04761174,CC(=O)C(=O)O.Nc1ccc(F)cc1F.O=N[O-]>>CC(=NNc1ccc(F)cc1F)C(=O)O,,Cl,O,Cl[Sn]Cl,,test
US20050159474A1,CC(C)(C)OC(=O)CC[C@H](N)C(=O)Nc1cccc(COc2ccc3[nH]c(C(N)=O)cc3c2)c1>>NC(=O)c1cc2cc(OCc3cccc(NC(=O)[C@@H](N)CCC(=O)O)c3)ccc2[nH]1,,C1COCCO1,ClCCl,Cl,,test
US06376655B1,CCOC(=O)CCCOc1ccc(N=Nc2ccc(C#N)cc2)cc1>>N#Cc1ccc(N=Nc2ccc(OCCCC(=O)O)cc2)cc1,,CN(C)C=O,O,Cl,[Na+].[OH-],test
US20120214766A1,CC(C)(CO)NC(=O)c1nn(-c2cncc(Cl)n2)c2c1C[C@H]1C[C@@H]21.CNC>>CN(C)c1cncc(-n2nc(C(=O)NC(C)(C)CO)c3c2[C@@H]2C[C@@H]2C3)n1,,C1CCOC1,,,,test
US20050153987A1,[O-][n+]1cc(CN2CCOCC2)ccc1-c1c(O)[nH]c2ccc(-c3cccnc3)cc12>>Oc1[nH]c2ccc(-c3cccnc3)cc2c1-c1ccc(CN2CCOCC2)cn1,,CCOC(C)=O,,ClP(Cl)Cl,,test
US20020177601A1,COc1cc2ncnc(Cl)c2cc1OC(C)=O.Nc1cccc(Br)c1>>COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC(C)=O,,CC(C)O,,,,test
US04075319,C=C(C)C(=O)OC.C=C(C)C(=O)[O-].C=C(C)C(=O)[O-].CCCC[Sn+](CCCC)CCCC.CCC[Sn+](CCC)CCC>>C=C(C)C(=O)OC.C=C(C)C(=O)O[Sn](CCC)(CCC)CCC.C=C(C)C(=O)[O-].CCCC[Sn+](CCCC)CCCC,,c1ccccc1,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US06162824,COC(=O)[C@H](COC1(c2ccccc2)c2ccccc2-c2ccccc21)NC(=O)OCC1c2ccccc2-c2ccccc21>>COC(=O)[C@@H](N)COC1(c2ccccc2)c2ccccc2-c2ccccc21,,C1CCNCC1,,,,test
US20110287937A1,CCOC(=O)c1cc2cccnc2n(Cc2ccccc2)c1=O>>O=C(O)c1cc2cccnc2n(Cc2ccccc2)c1=O,,C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US04061656,BrCc1ccsc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>[Br-].c1ccc([P+](Cc2ccsc2)(c2ccccc2)c2ccccc2)cc1,,c1ccccc1,,,,test
US20070105904A1,C#Cc1ccc(N)nc1.ON=C(Cl)Cc1ccc(Oc2ccc(F)cc2)nc1>>Nc1ccc(-c2cc(Cc3ccc(Oc4ccc(F)cc4)nc3)no2)cn1,,O,,C1CCOC1,CCN(CC)CC,test
US20050245554A1,CS(=O)(=O)c1ncc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1.NCc1cccc(Cl)c1>>Clc1ccc(-c2cnc(NCc3cccc(Cl)c3)nc2-c2ccc(Cl)cc2Cl)cc1,,CN(C)C=O,,,,test
US20150191474A1,CCSc1ccccc1-c1nc2ncc(C(F)(F)F)cc2c(=O)[nH]1.O=P(Cl)(Cl)Cl>>CCSc1ccccc1-c1nc(Cl)c2cc(C(F)(F)F)cnc2n1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20080039450A1,COc1cc(C(=O)O)ccc1Nc1cncc(-c2cc3cc(F)ccc3n2C(=O)OC(C)(C)C)n1.C[C@H]1CNCCN1>>COc1cc(C(=O)N2CCN[C@@H](C)C2)ccc1Nc1cncc(-c2cc3cc(F)ccc3[nH]2)n1,,CN(C)C=O,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,,test
US20040127552A1,COc1ccccc1S.C[C@@H](CO)CBr>>COc1ccccc1SC[C@@H](C)CO,,O,,[Na+].[OH-],,test
US05643932,COc1ccc(-c2nc(-c3ccc4c(c3)CCCN4)cs2)cc1OC.O=C(Cl)c1ccccc1>>COc1ccc(-c2nc(-c3ccc4c(c3)CCCN4C(=O)c3ccccc3)cs2)cc1OC,,c1ccncc1,,,,test
US20130059834A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1CCCC(NC(=O)c2c[nH]c3ncc(Br)nc23)C1>>CC(C)(C)OC(=O)NC1CCCC(NC(=O)c2c[nH]c3ncc(Br)nc23)C1,,C1CCOC1,,O,O=C([O-])[O-].[Na+].[Na+],test
US20090062279A1,CO/C=C/C(=O)OC.COc1cccc(NC(=O)OC(C)(C)C)c1C=O>>COC(=O)c1cnc2cccc(OC)c2c1,,CO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20150336876A1,BrCCCCBr.NCCCCC(Oc1ccc(C(F)(F)F)cc1)c1ccccc1>>FC(F)(F)c1ccc(OC(CCCCN2CCCC2)c2ccccc2)cc1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20010021714A1,Cc1noc(N)c1C.O=S(=O)(Cl)c1ccc(-c2ccccc2)cc1>>Cc1noc(NS(=O)(=O)c2ccc(-c3ccccc3)cc2)c1C,CN(C)c1ccncc1,c1ccncc1,,,,test
US20140275539A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N=C(N)NCc1cccc(I)c1>>CC(C)(C)OC(=O)NC(=N)N(Cc1cccc(I)c1)C(=O)OC(C)(C)C,,CS(C)=O,O,O=C(O)O,,test
US20090306064A1,CC(C)OB(OC(C)C)OC(C)C.Cc1cc(Br)cc(C)c1C#N>>Cc1cc(B(O)O)cc(C)c1C#N,,C1CCOC1,,Cl,[Li]CCCC,test
US20050085508A1,BrCc1ccccc1.OCCC1(CCO)CCCCC1>>OCCC1(CCOCc2ccccc2)CCCCC1,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20150005510A1,CO.N.O=C(O)CCC(=O)O>>CO.N.O=C(O)CCC(=O)O,,CO,,,,test
US20130259850A1,CCOC(=O)Cc1cccc(OCc2c(F)cccc2F)c1>>O=C(O)Cc1cccc(OCc2c(F)cccc2F)c1,,CCO,,[Na+].[OH-],,test
US20040010031A1,Nc1ccc(C(=O)c2ccccc2)cc1.O=C1NC(=O)C(c2ccc(Cl)cc2)=C1Cl>>O=C1NC(=O)C(c2ccc(Cl)cc2)=C1Nc1ccc(C(=O)c2ccccc2)cc1,,Cl,,CN1CCCC1=O,,test
US20120202691A1,COC1=C(c2cc(-c3ccc(Cl)cc3)sc2C)C(=O)CC1.O=CC1CCOCC1>>COC1=C(c2cc(-c3ccc(Cl)cc3)sc2C)C(=O)C(C(O)C2CCOCC2)C1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US05760032,CCOC(=O)CCC1N=C(c2ccccc2Cl)c2cc(CC)sc2-n2c(C)nnc21.O=C(Cl)c1ccc(Cl)c(Cl)c1.O=C([O-])O>>CCOC(=O)CCC(NC(=O)c1ccc(Cl)c(Cl)c1)c1nnc(C)n1-c1sc(CC)cc1C(=O)c1ccccc1Cl,,ClC(Cl)Cl,,Cl,,test
US04152433,C=[N+]=[N-].CC1C=C(C(=O)OCC(Cl)(Cl)Cl)N2C(=O)C(NC(=O)C(=NO)C(=O)CBr)[C@H]2S1>>CON=C(C(=O)CBr)C(=O)NC1C(=O)N2C(C(=O)OCC(Cl)(Cl)Cl)=CC(C)S[C@H]12,,CCO,CCOCC,,,test
US20100256113A1,BrCc1ccccc1.CCOC(=O)c1[nH]c2ccccc2c(=O)c1Cl>>CCOC(=O)c1nc2ccccc2c(OCc2ccccc2)c1Cl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090048239A1,COC(CN(C)S(=O)(=O)NC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)C[C@@H](N(C)CCNC(=O)OC(C)(C)C)COc1ccccc1-3)OC>>CN(CCN)[C@H]1COc2ccccc2-c2c(C3CCCCC3)c3ccc(C(=O)NS(=O)(=O)N(C)CC=O)cc3n2C1,,ClCCl,,O,O=C(O)C(F)(F)F,test
US20050153987A1,CNCCN1CCCC1.O=S(=O)(Cl)c1ccc(Cl)nc1>>CN(CCN1CCCC1)S(=O)(=O)c1ccc(Cl)nc1,,ClCCl,,,,test
US20130059832A1,Cc1ccc(C(N)=NO)cc1NC(=O)c1cnc2ccccn12.O=C(O)C1CCC(F)(F)CO1>>Cc1ccc(-c2noc(C3CCC(F)(F)CO3)n2)cc1NC(=O)c1cnc2ccccn12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110070317A1,CC(=O)Nc1c[nH]c2ncc(Br)c(F)c12.CC(C)(C)OC(=O)N[C@@H]1CCCNC1>>CC(=O)Nc1c[nH]c2ncc(Br)c(N3CCC[C@@H](NC(=O)OC(C)(C)C)C3)c12,,CCCCO,,CC#N,O,test
US20060052606A1,CCOC(=O)C(F)(F)F.O=C(NC(COCC1CCNCC1)c1ccccc1Cl)c1ccc2c(Cl)c[nH]c2c1>>O=C(NC(COCC1CCN(C(=O)C(F)(F)F)CC1)c1ccccc1Cl)c1ccc2c(Cl)c[nH]c2c1,,CO,,CCN(CC)CC,O,test
US20150080549A1,CC(C)C[C@@H](C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)SCc1ccccc1)C(=O)N(C)[C@@H](C)C(=O)N[C@@H](COC(C)(C)C)C(=O)NCC(N)=O)C(C)C)N(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](C)NC(=O)CNC(=O)OC(C)(C)C>>CC(C)C[C@@H](C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)SCc1ccccc1)C(=O)N(C)[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(N)=O)C(C)C)N(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](C)NC(=O)CN,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110184029A1,COc1ccc(OCC2(CO[Si](C)(C)C(C)(C)C)CC2)cc1>>COc1ccc(OCC2(CO)CC2)cc1,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080009492A1,COCCOc1cccc(-c2cc3cc([N+](=O)[O-])cnc3[nH]2)c1>>COCCOc1cccc(-c2cc3cc(N)cnc3[nH]2)c1,[Fe],CCO,,Cl,O,test
US20060264433A1,C[Si](C)(C)CN(CC#N)Cc1ccccc1.O=[N+]([O-])/C=C/c1cc(F)c(F)cc1Cl>>O=[N+]([O-])C1CN(Cc2ccccc2)CC1c1cc(F)c(F)cc1Cl,,CC#N,ClCCl,,,test
US20050222207A1,COc1cc(N(Cc2cncs2)c2ccc(C(=O)OC(C)(C)C)cc2)ccc1C(N)=O>>COc1cc(N(Cc2cncs2)c2ccc(C(=O)O)cc2)ccc1C(N)=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US05739140,COC(=O)c1ccccc1CBr.Oc1ccc(C2CCc3ccccc32)cc1>>COC(=O)c1ccccc1COc1ccc(C2CCc3ccccc32)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020022631A1,CC(C)(C)OC(=O)NC1=NC(Cc2ncc[nH]2)CS1>>NC1=NC(Cc2ncc[nH]2)CS1,,C1COCCO1,,CO,Cl,test
US20080096938A1,CCCCCCCCOc1ccc(C(C)=O)cc1C(F)(F)F.[N-]=[N+]=[N-]>>[N-]=[N+]=NCC(=O)c1ccccc1,,CO,ClCCl,CCOC(C)=O,,test
US05204346,O=S(=O)(c1ccccc1)c1ccc(-c2c(-c3ccccc3)nn3ccccc23)nn1>>O=c1ccc(-c2c(-c3ccccc3)nn3ccccc23)n[nH]1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20060030613A1,CON(C)C(=O)c1ccc(Br)cc1Cl.C[Mg]Cl>>CC(=O)c1ccc(Br)cc1Cl,,C1CCOC1,,,,test
US20150336878A1,CI.COC(=O)C(=NO)C(=O)OC>>CON=C(C(=O)OC)C(=O)OC,O=[Ag],CCOCC,,,,test
US06046210,COc1ccc2c(c1)CN(CCCCN1C(=O)c3ccccc3C1=O)CC2>>COc1ccc2c(c1)CN(CCCCN)CC2,,CCO,,NN,O,test
US05336663,Cn1c(C(F)(F)F)cc(=O)n(-c2ccc(Cl)c(CO)c2)c1=O>>Cn1c(C(F)(F)F)cc(=O)n(-c2ccc(Cl)c(C=O)c2)c1=O,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20100130492A1,CNc1ncc(B2OC(C)(C)C(C)(C)O2)cn1.Clc1nc(N2CCOCC2)c2ncn(CC3CC3)c2n1>>CNc1ncc(-c2nc(N3CCOCC3)c3ncn(CC4CC4)c3n2)cn1,,CCOC(C)=O,O,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20160157491A1,CC(=O)c1ccc2c(ccc3c2ncn3-c2ccc(OC(F)(F)F)cc2)c1.Cc1cccc(C)c1NC(=S)NN>>C/C(=N\NC(=S)Nc1c(C)cccc1C)c1ccc2c(ccc3c2ncn3-c2ccc(OC(F)(F)F)cc2)c1,,CCO,,,,test
US20120115856A1,Cc1nc2cc(-c3nc4ccccc4o3)ccc2n1CC(C)C(=O)OC(C)(C)C>>CC(=C=O)Cn1c(C)nc2cc(-c3nc4ccccc4o3)ccc21,,C1CCOC1,O,Cl,[Li+].[OH-],test
US06825200B1,CC1CN(C(=O)OC(C)(C)C)CCN1.O=[N+]([O-])c1ccc(F)cc1>>CC1CN(C(=O)OC(C)(C)C)CCN1c1ccc([N+](=O)[O-])cc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040229876A1,CCSc1nnc(N)s1.COc1cc2nccc(Oc3ccc(N)c(F)c3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCSc1nnc(NC(=O)Nc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2F)s1,,ClC(Cl)Cl,O,CCN(CC)CC,,test
US20130244966A1,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O.O=C(Cl)C(=O)Cl>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)Cl,CN(C)C=O,ClCCl,,,,test
US20110021512A1,CC(C)C1(CCCO)CCN([C@@H](C)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)C(=O)O1.C[C@@H](c1ccc(-c2cc[nH]c(=O)c2)cc1)N1CC[C@](CC(C)(C)C#N)(c2ccccc2)OC1=O>>CC(C)C1(CCCO)CCN([C@@H](C)c2ccc(-c3ccn(C)c(=O)c3)cc2)C(=O)O1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20110190272A1,CC(C)(C)[Si](C)(C)OCCN1CCCN(C(=O)OCc2ccccc2)CC1>>CC(C)(C)[Si](C)(C)OCCN1CCCNCC1,[Pd],CO,,,,test
US05198547,Nc1nc2c(c(=O)[nH]1)N[C@@H](CNc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1)CN2.O=CO>>Nc1nc2c(c(=O)[nH]1)N(C=O)[C@@H](CNc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1)CN2,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20140288123A1,CCOC(=O)c1cnc(Cl)nc1.Oc1ccccc1>>CCOC(=O)c1cnc(Oc2ccccc2)nc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050176689A1,CCOC(=O)C(C)(C)c1cccc(C#Cc2ccc(CC(=O)OC)c(F)c2)c1>>COC(=O)Cc1ccc(C#Cc2cccc(C(C)(C)C(=O)O)c2)cc1F,,C1CCOC1,CCO,[Li+].[OH-],,test
US20080255118A1,C1CCNCC1.CSc1nc(Cc2ccccc2)[nH]c(=O)c1C#N>>N#Cc1c(N2CCCCC2)nc(Cc2ccccc2)[nH]c1=O,,CC#N,,,,test
US20100228029A1,CCOC(=O)c1cc(OC)c(O)c(OC)c1.Cc1nc(C)c(CBr)nc1C>>CCOC(=O)c1cc(OC)c(OCc2nc(C)c(C)nc2C)c(OC)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05650415,CCOC(=O)c1cnc2c(F)ccc(F)c2c1Cl.FC(F)(F)c1cccc(S)c1>>CCOC(=O)c1cnc2c(F)ccc(F)c2c1Sc1cccc(C(F)(F)F)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20060025350A1,C=CCOC1O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](O[C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>C=CCOC1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,,C1CCOC1,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20060287287A1,ClI.NCc1ccc(N)c(Cl)c1>>NCc1cc(Cl)c(N)c(I)c1,,CO,,,,test
US05965553,CCOC(=O)C[C@H]1O[C@H](c2cccc3ccccc23)c2cc(Cl)ccc2N(CC(C)(C)CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C1=O>>CCOC(=O)C[C@H]1O[C@H](c2cccc3ccccc23)c2cc(Cl)ccc2N(CC(C)(C)CO)C1=O,,CC#N,O,O=C([O-])O.[Na+],,test
US20160185780A1,CC(C)(C)OC(=O)N1CC=C(c2cccn3nc(N)nc23)CC1>>Nc1nc2c(C3=CCNCC3)cccn2n1,,C1COCCO1,,Cl,,test
US20090324581A1,CCOC(=O)C(F)CN.O=C(CBr)N1CCc2cc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)ccc21>>CCOC(=O)C(F)CNCC(=O)N1CCc2cc(OCc3cc(-c4ccccc4)c(C(F)(F)F)s3)ccc21,,CC#N,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20110306612A1,COC(=O)c1cccc(C(=O)O)c1N.Nc1ccccn1>>COC(=O)c1cccc(C(=O)Nc2ccccn2)c1N,CN(C)c1ccncc1,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US06054470,CCCCCCBr.Cc1c(I)c[nH]c(=O)c1[N+](=O)[O-]>>CCCCCCn1cc(I)c(C)c([N+](=O)[O-])c1=O,,CN(C)C=O,,O,[H-].[Na+],test
US20050250770A1,C1COCCN1.Clc1nc(Cl)c2cc(Br)ccc2n1>>Clc1nc(N2CCOCC2)c2cc(Br)ccc2n1,,ClCCl,,,,test
US20160237091A1,C=Cc1cc2c(-c3ccnc(C)c3)nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c2cc1NC(C)=O.O=[Os](=O)(=O)=O>>CC(=O)Nc1cc2c(cc1C=O)c(-c1ccnc(C)c1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1,O=[Os](=O)(=O)=O,C1CCOC1,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20090042896A1,C[C@H](O)[C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccc(Cl)cc1.N#Cc1ccc(Cl)nc1>>C[C@H](Oc1ccc(C#N)cn1)[C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccc(Cl)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20090318465A1,CCOC(=O)CCN.CCOC(=O)c1ccc([N+](=O)[O-])cc1CBr>>CCOC(=O)CCN1Cc2cc([N+](=O)[O-])ccc2C1=O,,CN(C)C=O,ClCCl,Cl,O=C([O-])O.[Na+],test
US05994368,CCOC(=O)C(C)C(C)=O.COc1ccccc1N>>CCOC(=O)C(C)=C(C)Nc1ccccc1OC,,c1ccccc1,,CC(=O)O,,test
US20090023941A1,C=C(C)C(CO)CC=C(C)C.CS(=O)(=O)Cl>>C=C(C)C(CC=C(C)C)COS(C)(=O)=O,,O,,CCN(CC)CC,Cc1ccccc1,test
US04446141,CCn1c(=O)n(C2CCN(CC(=O)c3ccc4c(c3)OCO4)CC2)c2ccccc21>>CCn1c(=O)n(C2CCN(CC(O)c3ccc4c(c3)OCO4)CC2)c2ccccc21,,CO,,[BH4-].[Na+],,test
US20080070920A1,CCOP(=O)(CC#N)OCC.COc1ccc(CNc2cc(Cn3c(Oc4cc(C)cc(C=O)c4)c(C(C)C)c(=O)[nH]c3=O)cc(Cl)n2)cc1>>COc1ccc(CNc2cc(Cn3c(Oc4cc(C)cc(C=CC#N)c4)c(C(C)C)c(=O)[nH]c3=O)cc(Cl)n2)cc1,,C1CCOC1,CCOC(C)=O,CC(C)(C)[O-].[K+],,test
US20150126449A1,C1CCOC1.CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4c(Br)cccc4nn23)CC1.Fc1cc(F)cc(Br)c1>>COc1cccc(F)c1-c1cccc2nn3c(C4CCN(C(=O)OC(C)(C)C)CC4)cc(=O)[nH]c3c12,,CCOC(C)=O,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20040077877A1,CCON=Cc1ccc2[nH]nc(-c3cccc(C(=O)NC4CCC4)c3)c2c1.CN(C)CC(=O)NN>>CN(C)Cc1n[nH]c(-c2ccc3[nH]nc(-c4cccc(C(=O)NC5CCC5)c4)c3c2)n1,,CO,,C[O-].[Na+],,test
US20110230461A1,CCOC(=O)C(C#N)c1ccc(OC)cc1[N+](=O)[O-]>>COc1ccc(CC#N)c([N+](=O)[O-])c1,,CCOC(C)=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20070032478A1,Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3)c1.O=C(Cl)c1cccs1>>O=C1Cc2ccc(C(=O)c3cccc(NC(=O)c4cccs4)c3)cc2N1,,C1CCOC1,,,,test
US20060100283A1,CC(C)(C)OC(=O)N(Cc1ccccc1)[C@@H]1CC[C@@H](c2ccc(O)cc2)CC1.CCOC(=O)CBr>>CCOC(=O)COc1ccc([C@@H]2CC[C@@H](N(Cc3ccccc3)C(=O)OC(C)(C)C)CC2)cc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20140350019A1,COC(=O)c1c(F)ccc(O)c1F.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1c(F)ccc(OS(=O)(=O)C(F)(F)F)c1F,,ClCCl,O,Cl,c1ccncc1,test
US06194454B1,COc1ccc(O)cc1C(C)C.Cc1cc([N+](=O)[O-])cc(C#N)c1Cl>>COc1ccc(Oc2c(C)cc([N+](=O)[O-])cc2C#N)cc1C(C)C,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040254200A1,CCOC(=O)c1sc2c(ccc(=O)n2-c2ccc(CO)cc2)c1-c1ccccc1.O=S(Cl)Cl>>CCOC(=O)c1sc2c(ccc(=O)n2-c2ccc(CCl)cc2)c1-c1ccccc1,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20160244465A1,CC(F)(F)[C@H]1OC[C@]2(c3cc(NC(=O)c4cnc(-n5cncn5)cn4)ccc3F)N=C(N)SC[C@H]12.Cc1ccc(S(=O)(=O)O)cc1>>CC(F)(F)[C@H]1OC[C@]2(c3cc(NC(=O)c4cnc(-n5cncn5)cn4)ccc3F)N=C(N)SC[C@H]12.Cc1ccc(S(=O)(=O)O)cc1,,CC(C)=O,O,,,test
US20150094297A1,CC(C)(C)[Si](C)(C)OCc1csc(Br)n1.CN(C)C(=O)c1ccc(B(O)O)cc1>>CN(C)C(=O)c1ccc(-c2nc(CO[Si](C)(C)C(C)(C)C)cs2)cc1,,CCO,Cc1ccccc1,ClCCl,O=C([O-])[O-].[Na+].[Na+],test
US20140378433A1,CC1(C)CN(C2CCOCC2)C(=O)c2c(nc(N3CC4CCC(C3)O4)nc2-c2ccc(NC(=O)Oc3ccccc3)cc2)O1.Cc1cc(N)no1>>Cc1cc(NC(=O)Nc2ccc(-c3nc(N4CC5CCC(C4)O5)nc4c3C(=O)N(C3CCOCC3)CC(C)(C)O4)cc2)no1,,C1CCOC1,,CN(C)C=O,,test
US20060166997A1,COc1cc(F)ccc1OC(C)=O.ClI>>COc1cc(F)c(I)cc1OC(C)=O,,ClCCl,,,,test
US20140213582A1,BrCC1CO1.CC(C)(C)OC(=O)N1CCNC(=O)C1>>CC(C)(C)OC(=O)N1CCN(CC2CO2)C(=O)C1,,C1CCOC1,,[H-].[Na+],,test
US20150018343A1,Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccccc1OC[C@H]1CCCN1C(=O)OC(C)(C)C)C3>>Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccccc1OC[C@H]1CCCN1)C3,,ClCCl,,Cl,,test
US20050143443A1,CCOC(=O)C(=O)C1CCC(C)C1=O.NN>>CCOC(=O)c1n[nH]c2c1CCC2C,,CCO,,O,,test
US20040102439A1,CCOC(=O)[C@H](Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)NCc1ccc(F)cc1.CI>>CCOC(=O)[C@H](Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)N(C)Cc1ccc(F)cc1,,C1CCOC1,,O,[H-].[Na+],test
US20040077653A1,CCCc1cc(Cl)nnc1Cn1ccnc1-c1cccc(F)n1>>CCCc1ccnnc1Cn1ccnc1-c1cccc(F)n1,[Pd],CCO,,O=C([O-])[O-].[K+].[K+],,test
US20160218292A1,Brc1c2ccccc2c(-c2ccc3ccccc3c2)c2ccccc12.CC1(C)OB(c2cccc(B3OC(C)(C)C(C)(C)O3)c2)OC1(C)C>>CC1(C)OB(c2cccc(-c3c4ccccc4c(-c4ccc5ccccc5c4)c4ccccc34)c2)OC1(C)C,,Cc1ccccc1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US08815901B2,CN1CCN(Cc2ccc(N)nc2)CC1.COc1cc(OC)c(Cl)c(-c2ccc(C(=O)O)c3ncccc23)c1Cl>>COc1cc(OC)c(Cl)c(-c2ccc(C(=O)Nc3ccc(CN4CCN(C)CC4)cn3)c3ncccc23)c1Cl,,CO,ClCCl,,,test
US20080076745A1,CC(C)(C)OC(=O)NCCC[C@@H](CC(=O)NCCNC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1.Cl>>Cl.NCCC[C@@H](CC(=O)NCCNC(=O)OCc1ccccc1)N(Cc1ccccc1)C(=O)O,,C1COCCO1,,,,test
US06586431B1,COc1cccc(C(C#N)c2ccc(Br)cn2)c1.ClCCCBr>>COc1cccc(C(C#N)(CCCCl)c2ccc(Br)cn2)c1,,CCOCC,CN(C)C=O,CCCCCC,[H-].[Na+],test
US20130296340A1,COC=C(C=CC(=O)OC)C(=O)OC.Nc1nccs1>>COC(=O)c1ccc(=O)n(-c2nccs2)c1,,CN(C)C=O,,,,test
US20060270706A1,CCOC(=O)CCn1ccc(/C=C2\CN(C(C(=O)C3CC3)c3ccccc3F)CC[C@H]2S)n1.Cl>>Cl.O=C(O)CCn1ccc(/C=C2\CN(C(C(=O)C3CC3)c3ccccc3F)CC[C@H]2S)n1,,CC#N,,,,test
US20150158815A1,NC(=O)C(Nc1cncc(Br)c1)c1ccccc1.OB(O)c1cc(Cl)ccc1F>>NC(=O)C(Nc1cncc(-c2cc(Cl)ccc2F)c1)c1ccccc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20140336172A1,COCCNC(=O)c1ccc2nn(CC3CCNCC3)cc2c1C.O=C(Cl)c1ccc(SC(F)(F)F)cc1>>COCCNC(=O)c1ccc2nn(CC3CCN(C(=O)c4ccc(SC(F)(F)F)cc4)CC3)cc2c1C,,ClCCl,,CCN(CC)CC,Cl,test
US20130131018A1,CCOc1cccc(CNCC(OCC)OCC)c1O.COc1cc(C=O)cc(OC)c1OCCc1ccccc1.Cl>>CCOc1ccc2c(Cc3cc(OC)c(OCCc4ccccc4)c(OC)c3)cncc2c1O.Cl,,CCO,,CO,,test
US06518273B1,CI.COc1ccccc1N1CCN(C(=O)CCc2c(-c3ccc(Cl)cc3)[nH]c3ccc(C)cc23)CC1>>COc1ccccc1N1CCN(C(=O)CCc2c(-c3ccc(Cl)cc3)n(C)c3ccc(C)cc23)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US20090258855A1,C1CCOC1.CCN.Cn1cc(-c2ccc3nnc(Sc4ccc([N+](=O)[O-])c(F)c4)n3n2)cn1>>CCn1cnc2ccc(Sc3nnc4ccc(-c5cnn(C)c5)nn34)cc21,[Fe],,,,,test
US20120245137A1,CC1(S(=O)(=O)c2cccc(C(F)(F)F)c2)CCC(=O)CC1.NCc1ccccc1>>CC1(S(=O)(=O)c2cccc(C(F)(F)F)c2)CCC(NCc2ccccc2)CC1,,ClCCCl,,CC(=O)O,,test
US20070078121A1,O=[N+]([O-])c1cccc(F)c1.Oc1cncc(Cl)c1>>O=[N+]([O-])c1cccc(Oc2cncc(Cl)c2)c1,,CS(C)=O,,[H-].[Na+],,test
US20050176706A1,CC(C)(C)OC(=O)Nc1cccnc1C#C[Si](C)(C)C>>c1cnc2cc[nH]c2c1,,C1CCOC1,CCOCC,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090264414A1,CC1(C)CC2CC(C)(CN2C(=O)c2ccc3c(C(=O)C(Cl)(Cl)Cl)c[nH]c3c2)C1.[OH-]>>CC1(C)CC2CC(C)(CN2C(=O)c2ccc3c(C(=O)O)c[nH]c3c2)C1,,C1CCOC1,,CCO,,test
US20100174065A1,CC(C)(C)OC(=O)N1CCOc2c(O)cccc2C1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(C)(C)OC(=O)N1CCOc2c(cccc2OS(=O)(=O)C(F)(F)F)C1,,c1ccncc1,,,,test
US20100105900A1,C[N+](C)(C)C[C@@H](CC(=O)[O-])NC(=O)c1cccc(C#Cc2ccccc2)c1>>C[N+](C)(C)C[C@@H](CC(=O)[O-])NC(=O)c1cccc(CCc2ccccc2)c1,[Pd],,,,,test
US20150299179A1,CC(C)Oc1ccc(-c2nsc(-c3cccc4c3CC[C@@H]4NC(=O)OC(C)(C)C)n2)cc1C#N.Cl>>CC(C)Oc1ccc(-c2nsc(-c3cccc4c3CC[C@@H]4N)n2)cc1C#N.Cl,,C1COCCO1,CCOCC,,,test
US05919793,N.O=C(Cl)Cc1ccc(I)cc1>>NC(=O)Cc1ccc(I)cc1,,CCOCC,,,,test
US05114939,Fc1cccc2c(Cl)ccnc12.OCCc1ccc(Cl)cc1>>Fc1cccc2c(OCCc3ccc(Cl)cc3)ccnc12,,CN(C)C=O,,[H-].[Na+],,test
US05240925,CC1CN(CCCCO)CC(C)O1.ClC(Cl)Cl.O=S(Cl)Cl>>CC1CN(CCCCCl)CC(C)O1.Cl,,CCOCC,,,,test
US20140179667A1,COC(CN(Cc1cc(Br)cc(OC(C)C)c1C)S(=O)(=O)c1ccc(C)cc1)OC>>Cc1c(OC(C)C)cc(Br)c2ccncc12,,C1COCCO1,Cl,,,test
US20120184553A1,COc1cccc(COC(=O)c2cc(Br)ccc2OCc2cccc(OC)c2)c1>>COc1cccc(COc2ccc(Br)cc2C(=O)O)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20030130238A1,COC(=O)C1CN(C(C)=O)c2ccccc2CN1S(=O)(=O)c1ccc(OC)cc1>>COC(=O)C1CN(C(C)=O)c2ccccc2CN1S(=O)(=O)c1ccc(O)cc1,,ClCCl,,BrB(Br)Br,O,test
US20150065482A1,Cc1cc(Cl)c(C=O)cn1.NN>>Cc1cc2[nH]ncc2cn1,,COCCOC,,O,,test
US20150320892A1,CC(C)(C)OC(=O)NCCN(CC(CC(=O)ON1C(=O)CCC1=O)CN(CCNC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.CC1(C)[C@@H]2C[C@H]1CC1OB([C@@H]3CCCN3C(=O)CNC(=O)CCCCCN)O[C@]12C>>CC(C)(C)OC(=O)NCCN(CC(CC(=O)NCCCCCC(=O)NCC(=O)N1CCC[C@H]1B1OC2C[C@@H]3C[C@@H](C3(C)C)[C@]2(C)O1)CN(CCNC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,ClCCl,,CN1CCOCC1,,test
US04792561,O=C1CCc2cc(Br)ccc2N1.c1c[nH]cn1>>O=C1CCc2cc(-n3ccnc3)ccc2N1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070276000A1,CCCCCC#Cc1cc(OC)ccc1C(=O)Cc1ccccc1>>CCCCCc1cc2cc(OC)ccc2c(O)c1-c1ccccc1,,Cc1ccccc1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20110152531A1,COC(=O)C(=O)/C=C1\COC(C)(C)O1.NNc1ncccc1Cl>>COC(=O)C1(O)CC(CO)=NN1c1ncccc1Cl,,CC(C)O,,,,test
US20160165887A1,FC(F)(CBr)c1ccc(Cl)cc1Cl.[N-]=[N+]=[N-]>>[N-]=[N+]=NCC(F)(F)c1ccc(Cl)cc1Cl,,CS(C)=O,,O,,test
US20100331335A1,C/C(=C\C(=O)c1sccc1NC(=O)Cc1cccc2ccccc12)N(C)C.NN>>Cc1cc(-c2sccc2NC(=O)Cc2cccc3ccccc23)n[nH]1,,CCO,,CC(=O)O,O,test
US04337341,BrCC1CCCO1.Oc1cccc(C23CCCC2CNCC3)c1>>Oc1cccc(C23CCCC2CN(CC2CCCO2)CC3)c1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20070225280A1,CCOC(=O)c1cnn(C(C)(C)C)c1-c1cc(Cl)on1>>CC(C)(C)n1ncc(C(=O)O)c1-c1cc(Cl)on1,,CCO,,[Li+].[OH-],,test
US20020049226A1,COc1ccc(C=O)cc1OCc1ccccc1.OO>>COc1ccc(O)cc1OCc1ccccc1,,CO,,O=S(=O)(O)O,,test
US20100022598A1,CCC(C)(C)Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c(CC(N)c2ccc(-c3ccc(F)cn3)cc2)n1.CS(=O)(=O)Cl>>CCC(C)(C)Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c(CC(NS(C)(=O)=O)c2ccc(-c3ccc(F)cn3)cc2)n1,,ClCCl,,CCN(CC)CC,,test
US20110311474A1,CC[C@@H]1C[C@H](NS(=O)(=O)C2CC2)C[C@@H]1N.O=[N+]([O-])c1cnc2[nH]ccc2c1Cl>>CC[C@@H]1C[C@H](NS(=O)(=O)C2CC2)C[C@@H]1Nc1c([N+](=O)[O-])cnc2[nH]ccc12,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,Cl,test
US20100144760A1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H]2C[C@H]1CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>CC(C)(C)OC(=O)N1C[C@@H]2C[C@@H]2C[C@H]1CO,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090214675A1,CC(N)=CC(=O)CC1CCCC1.CC([O-])=CC#N.Cc1cc(=O)c2cccc(C=O)c2o1>>CC1=C(C#N)C(c2cccc3c(=O)cc(C)oc23)C(C(=O)CC2CCCC2)=C(C)N1,,CC(C)O,,CC(=O)O,,test
US20020002164A1,Clc1cc(Cl)cc(CO[C@H]2OCCN(Cc3ccccc3)[C@H]2c2ccccc2)c1>>Clc1cc(Cl)cc(CO[C@H]2OCCN[C@H]2c2ccccc2)c1,,ClCCCl,,CC(Cl)OC(=O)Cl,,test
US04393240,CC(C)(C)OC[C@H](CP(c1ccccc1)c1ccccc1)P(c1ccccc1)c1ccccc1>>OC[C@H](CP(c1ccccc1)c1ccccc1)P(c1ccccc1)c1ccccc1,,O=C(O)C(F)(F)F,,,,test
US20120202691A1,CC(O)c1cnc(-c2ccc(Cl)cc2)s1.O=C1CCC(=O)C1>>CC(OC1=CC(=O)CC1)c1cnc(-c2ccc(Cl)cc2)s1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05474994,COc1ccccc1N1CCN(CC(C)(C)O)CC1.Cc1c(-c2ccccc2)oc2c(C(=O)Cl)cccc2c1=O.ClCCCl>>COc1ccccc1N1CCN(CC(C)(C)OC(=O)c2cccc3c(=O)c(C)c(-c4ccccc4)oc23)CC1.Cl.Cl,,ClCCCl,ClCCl,O,[Na+].[OH-],test
US20110092485A1,CC(C)(C)[Si](C)(C)OCCBr.O=C(O)Cc1ccc(Br)cc1>>O=C1OCCC1c1ccc(Br)cc1,,C1CCOC1,,Cl,CC(C)[N-]C(C)C.[Li+],test
US06660744B1,CN1CCN([C@H]2CC[C@@H](n3nc(I)c4c(N)ncnc43)CC2)CC1.COc1cc(B(O)O)ccc1C(=O)NCc1ccccc1>>COc1cc(-c2nn([C@@H]3CC[C@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1C(=O)NCc1ccccc1,,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20140005213A1,COCC(C)O.Cc1ccc2cccc(O)c2n1>>COCC(C)Oc1cccc2ccc(C)nc12,,C1CCOC1,O,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040014751A1,Cc1cc(Cl)nc2c1c(=O)cc(Nc1ccccc1)n2-c1ccccc1.O=C=Nc1ccc(F)cc1>>Cc1cc(Cl)nc2c1c(=O)cc(N(C(=O)Nc1ccc(F)cc1)c1ccccc1)n2-c1ccccc1,,ClCCl,,,,test
US20100063293A1,CC(NC(=O)c1cc(Cl)ccc1[N+](=O)[O-])C1CC1>>CC(NC(=O)c1cc(Cl)ccc1N)C1CC1,,CCO,,Cl,O,test
US20100210632A1,COC(=O)C(=O)CC(=O)c1ccc(OC)cc1.Nc1ccc(-c2ccon2)cc1.O=Cc1cccc(F)c1>>COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccc(-c4ccon4)cc3)C2c2cccc(F)c2)cc1,,C1COCCO1,,CCOCC,,test
US20130338179A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCCCc1cc(Cl)nc(Cl)n1.CN[C@H]1CCNC1>>CCCCc1cc(N2CC[C@H](N(C)C(=O)OC(C)(C)C)C2)nc(Cl)n1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,,test
US07071175B1,CCOC(=O)C(C)(CO)Cc1cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(C)c1.O=C(O)Cc1cccs1>>CCOC(=O)C(C)(CSC(C)=O)Cc1cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(C)c1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100316601A1,BrB(Br)Br.COc1c(N)cc(C)cc1-c1ccc(C(=O)O)s1>>Br.Cc1cc(N)c(O)c(-c2ccc(C(=O)O)s2)c1,,ClCCl,,,,test
US05047518,CO.ClC(Cl)Cl.O=C1C[C@H](OCc2ccccc2)[C@H]2CO[C@@H]1O2>>COC1(OC)C[C@H](OCc2ccccc2)[C@H]2CO[C@@H]1O2,,Cl,,,,test
US20140201855A1,CC1=CC(C)(C)Nc2ccc(NC(=O)OC(C)(C)C)cc21.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CC1=CC(C)(C)N(C(=O)C(F)(F)F)c2ccc(NC(=O)OC(C)(C)C)cc21,,ClCCl,c1ccncc1,,,test
US20120295884A1,CCOC(=O)c1cc(Br)c(F)c([N+](=O)[O-])c1>>CCOC(=O)c1cc(N)c(F)c(Br)c1,[Ni],CCO,,,,test
US20040214817A1,COc1cccc2c1OCO2.O=[N+]([O-])O>>COc1cc([N+](=O)[O-])cc2c1OCO2,,CC(=O)OC(C)=O,,,,test
US20110312963A1,Nc1cc(O)ccn1.O=[N+]([O-])c1ccc(F)c2ccccc12>>Nc1cc(Oc2ccc([N+](=O)[O-])c3ccccc23)ccn1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20040254167A1,C[C@@H]1C(=O)NCCCN1C(=O)C[C@@H](Cc1cc(F)c(F)cc1F)NC(=O)OC(C)(C)C.Cl>>C[C@@H]1C(=O)NCCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F.Cl,,C1COCCO1,,,,test
US20090137580A1,Cn1ccc2ncnc(Oc3ccc(N)c(Cl)c3)c21.Nc1cccc(-n2ccnc2)c1.O=C(Cl)Oc1ccccc1>>Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(-n5ccnc5)c4)c(Cl)c3)c21,,CC(=O)N(C)C,,c1ccncc1,,test
US04740233,COC(=O)CC(=O)OC.Nc1n[nH]c(SCc2ccccc2)n1>>Oc1cc(O)n2nc(SCc3ccccc3)nc2n1,,CCO,CO,C[O-].[Na+],,test
US20110263575A1,COC(=O)C1(CN[C@@H]2CCC(F)(F)C2)CC1.O=[N+]([O-])c1cnc(Cl)nc1Cl>>COC(=O)C1(CN(c2nc(Cl)ncc2[N+](=O)[O-])[C@@H]2CCC(F)(F)C2)CC1,,ClCCl,,O=C([O-])O.[Na+],,test
US20020082270A1,C[C@@H](Nc1ncnc2cc(OCCN3CCNCC3)c([N+](=O)[O-])cc12)c1ccccc1.O=C1C=CCO1>>C[C@@H](Nc1ncnc2cc(OCCN3CCN(C4COC(=O)C4)CC3)c([N+](=O)[O-])cc12)c1ccccc1,,CO,,,,test
US20090192136A1,CC(=O)c1ccc(N2CCN(C(=O)c3cc(Br)ccc3N3CCOCC3)CC2)c(F)c1.c1c[nH]cn1>>CC(=O)c1ccc(N2CCN(C(=O)c3cc(-n4ccnc4)ccc3N3CCOCC3)CC2)c(F)c1,[Cu]I,C1COCCO1,,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US20150164876A1,CC(=O)Cl.CN(CCN1CCNCC1)C(=O)c1cccc(C(=O)Nc2ccc(N3CCCCC3)cc2-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1>>CC(=O)N1CCN(CCN(C)C(=O)c2cccc(C(=O)Nc3ccc(N4CCCCC4)cc3-c3cc(C(=O)NCc4cccc(C(F)(F)F)c4)ccn3)c2)CC1,,ClCCl,,CCN(CC)CC,,test
US03950528,CCOC(=O)C=C(N)OCC.NNCc1cccc(I)c1>>Nc1cc(=O)n(Cc2cccc(I)c2)[nH]1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20160137626A1,C=Cc1ccc2cc(NC(=O)OCc3ccccc3)c(C(=O)Nc3cnccc3N3C[C@@H](NC(=O)OC(C)(C)C)[C@@H](NC(=O)OC)[C@@H](C)C3)nc2c1>>CCc1ccc2cc(N)c(C(=O)Nc3cnccc3N3C[C@@H](N)[C@@H](NC(=O)OC)[C@@H](C)C3)nc2c1,[Pd],CO,,,,test
US20140200344A1,CI.CON(C)C(=O)[C@@H]1CC[C@@H](O)CC1>>CO[C@@H]1CC[C@@H](C(=O)N(C)OC)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US20160108027A1,CC1CNC(C2CC(O)C2)CO1.COc1cc(C(=O)O)cc2nc(NCc3cc(Cl)ccn3)oc12>>COc1cc(C(=O)N2CC(C)OCC2C2CC(O)C2)cc2nc(NCc3cc(Cl)ccn3)oc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04472305,CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC(=O)c1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)O,[Pd],CCO,CO,,,test
US20100204235A1,CNC(=O)c1cccc(-c2cnn3c(Br)cnc3c2)c1.OB(O)c1ccnc(Cl)c1>>CNC(=O)c1cccc(-c2cnn3c(-c4ccnc(Cl)c4)cnc3c2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US05705456,CC(C)(CCl)C(=O)NC1CCN(c2cccc(OC(F)(F)F)c2)C1=O>>CC1(C)CN(C2CCN(c3cccc(OC(F)(F)F)c3)C2=O)C1=O,,C1CCOC1,,O,[Na+].[OH-],test
US05610144,COC(=O)Cc1cccc(NC(=O)NCC(=O)N2C(c3ccccc3)CCC2c2cccc(O)c2)c1>>O=C(O)Cc1cccc(NC(=O)NCC(=O)N2C(c3ccccc3)CCC2c2cccc(O)c2)c1,,CO,,,,test
US20020049194A1,CCOC(=O)CBr.O=C(c1ccc([N+](=O)[O-])cc1Cl)N1C=CC=Nc2ccccc21>>CCOC(=O)CN1CCCN(C(=O)c2ccc([N+](=O)[O-])cc2Cl)c2ccccc21,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20040152697A1,CCOC(=O)C(CCBr)N=[N+]=[N-].C[C@@H](N)C(=O)OC(C)(C)C>>C[C@H](C(=O)OC(C)(C)C)N1CCC(N=[N+]=[N-])C1=O,,CC#N,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20120245209A1,COc1c([N+](=O)[O-])c(F)c(F)c2c1[nH]c(=O)n2-c1ccc(Br)cc1F>>COc1c(N)c(F)c(F)c2c1[nH]c(=O)n2-c1ccc(Br)cc1F,[Zn],,,,,test
US20110082120A1,COC(=O)c1cc(NC(=O)CSSCCNC(=O)OC(C)(C)C)ccc1O>>COC(=O)c1cc(NC(=O)CSSCCN)ccc1O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060128710A1,CC(C)(C)c1ccc(N)cc1.Clc1ncnc2c1CCN(Cc1ccccc1)C2>>CC(C)(C)c1ccc(Nc2ncnc3c2CCN(Cc2ccccc2)C3)cc1,,C1CCOC1,,c1ccncc1,O=C([O-])O.[Na+],test
US05068404,COP(=O)(CN(C(C)C)C(C)C(=O)O)OC>>O=C(O)CNCP(=O)(O)O,,O,,[Na+].[OH-],,test
US20150368240A1,C[Si](C)(C)C#Cc1ccnc(C(=O)N2CCc3nc(NC4Cc5ccccc5C4)ncc3C2)c1>>C#Cc1ccnc(C(=O)N2CCc3nc(NC4Cc5ccccc5C4)ncc3C2)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20020137741A1,CCOC(=O)c1cnc2cc(F)c(F)cc2c1Cl>>CCOC(=O)c1cnc2cc(F)c(F)cc2c1,[Pd],CCO,,CCN(CC)CC,,test
US20160122342A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.COC(=O)c1cccc(N)c1Br>>COC(=O)c1cccc(NC2CCN(C(=O)OC(C)(C)C)CC2)c1Br,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20080293666A1,CC(C)(C)[Si](C)(C)O[C@@H]1C[C@@H](COS(=O)(=O)NC(=O)c2ccccc2OCc2ccccc2)O[C@H]1n1cnc2c(N)ncnc21.CC[NH+](CC)CC>>CC[NH+](CC)CC.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COS(=O)(=O)NC(=O)c2ccccc2O)C[C@H]1O,[Pd],CO,,O=C(O)C(F)(F)F,,test
US05972975,CC(=O)Nc1cc(C(=O)O)ccn1.CO>>COC(=O)c1ccnc(NC(C)=O)c1,,CO,c1ccccc1,C[Si](C)(C)C=[N+]=[N-],,test
US20100093757A1,CC(C)(C)[Si](OCCOC[C@H](Oc1ncnc2c1nnn2-c1ccccc1Cl)C(=O)Nc1ccc(Cl)cn1)(c1ccccc1)c1ccccc1>>O=C(Nc1ccc(Cl)cn1)[C@H](COCCO)Oc1ncnc2c1nnn2-c1ccccc1Cl,,CO,,Cl,,test
US20020007059A1,Cc1ccc2nsnc2c1.O=C1CCC(=O)N1Br>>BrCc1ccc2nsnc2c1,,ClC(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US04740524,CCOC(=O)C(CBr)=NO.O=C(Cl)c1ccc(Cl)cc1>>CCOC(=O)C(CBr)=NOC(=O)c1ccc(Cl)cc1,,ClCCl,,c1ccncc1,,test
US20160120850A1,OCc1nc(CC2CCC2)cs1>>O=Cc1nc(CC2CCC2)cs1,,CC(C)=O,,,,test
US20110306626A1,CCOC(=O)CBr.O=C1NC2(CCCCC2)N=C1c1ccccc1>>CCOC(=O)CN1C(=O)C(c2ccccc2)=NC12CCCCC2,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100286126A1,CCNC(=O)[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(N4CC[C@@H](N)C4)nc32)[C@H](O)[C@@H]1O.COc1c(OC)c(=O)c1=O>>CCNC(=O)[C@H]1O[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(N4CC[C@@H](Nc5c(OC)c(=O)c5=O)C4)nc32)[C@H](O)[C@@H]1O,CN(C)c1ccncc1,CCO,,O=C(O)C(F)(F)F,,test
US20150329523A1,CCOC(=O)c1cc(C(C)(C)C)nn1-c1ccc(N(C)C)cc1>>CN(C)c1ccc(-n2nc(C(C)(C)C)cc2C(=O)O)cc1,,C1CCOC1,O,CO,[Na+].[OH-],test
US20070232583A1,CC(C)(C)O.Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccnc(-c3cccc(N)c3)n2)n1.O=C=NS(=O)(=O)Cl>>Cc1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccnc(-c3cccc(NS(=O)(=O)NC(=O)OC(C)(C)C)c3)n2)n1,,ClCCl,ClCCl,CCN(CC)CC,,test
US20040157909A1,Cc1cc(C)c(C=O)[nH]1.O=C1Cc2c(cccc2-c2ccc(Br)cc2)N1>>Cc1cc(C)c(C=C2C(=O)Nc3cccc(-c4ccc(Br)cc4)c32)[nH]1,C1CCNCC1,CCO,,,,test
US20050239841A1,BrBr.COc1ccc(CO)cc1OC(F)(F)F>>COc1ccc(CBr)cc1OC(F)(F)F,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04937350,CC(=O)O.Nc1nc(S)n[nH]1>>CC(=O)Nc1nc(S)n[nH]1,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20060173041A1,CC(C)(C)OC(=O)C(CS(=O)(=O)N1CCC(Oc2ccc(F)cc2Br)CC1)C1CCCC1>>O=C(O)C(CS(=O)(=O)N1CCC(Oc2ccc(F)cc2Br)CC1)C1CCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06140274,FC(F)(F)C(Cl)(Cl)Cl.O=CCOCCCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl>>FC(F)(F)/C(Cl)=C/COCCCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl,[Zn],CN(C)C=O,,CC(=O)OC(C)=O,,test
US20030083357A1,CCOc1cc(C=O)ccc1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOc1cc(C=O)ccc1S(=O)(=O)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US20080167303A1,CC(C)(C)OC(=O)N1CCN(CCN2c3ccccc3N(c3ccccc3Cl)S2(=O)=O)CC1>>O=S1(=O)N(CCN2CCNCC2)c2ccccc2N1c1ccccc1Cl,,C1COCCO1,ClCCl,Cl,,test
US04176185,O=C(O)CCCl.Oc1cccc2ncccc12>>O=C(O)CCOc1cccc2ncccc12,,[K+],[OH-],,,test
US20150296788A1,COC(OC)N(C)C.O=C1CCCc2ccc(Cl)nc21>>CN(C)/C=C1\CCc2ccc(Cl)nc2C1=O,,CCOC(C)=O,,,,test
US20030166634A1,CC1(C)CC(=O)CC(C)(C)C1.CCOP(=O)(CC#N)OCC>>CC1(C)CC(=CC#N)CC(C)(C)C1,,C1CCOC1,,[H-].[Na+],,test
US20150045408A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C1CCN(Cc2ccccc2)C1>>COC(=O)C1CCN(C(=O)OC(C)(C)C)C1,[Pd],CO,,,,test
US20100249146A1,Cc1cc(B(O)O)cnc1F.OO>>Cc1cc(O)cnc1F,,O,,C1CCOC1,,test
US20150166513A1,COc1ccc(S(C)(=O)=O)cc1CBr.Cc1cnc(Cl)nc1N>>COc1ccc(S(C)(=O)=O)cc1CNc1nc(Cl)ncc1C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090136473A1,COc1ccc(Cc2ccc(F)nc2)c(F)c1-c1cccc(Cl)c1.O=C(O)[C@H]1CCN1>>COc1ccc(Cc2ccc(N3CC[C@@H]3C(=O)O)nc2)c(F)c1-c1cccc(Cl)c1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20120029026A1,COC(=O)c1cccc(OCc2nc3ccc(O)cc3n2C)c1.Fc1ncccc1Br>>COC(=O)c1cccc(OCc2nc3ccc(Oc4ncccc4Br)cc3n2C)c1,I[Cu]I,CN(C)C=O,,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US20070232673A1,CN(CCCN)C(=O)OC(C)(C)C.O=[N+]([O-])c1cccc(Cl)c1Cl>>CN(CCCNc1c(Cl)cccc1[N+](=O)[O-])C(=O)OC(C)(C)C,,CCOCC,Cl,CCN(C(C)C)C(C)C,,test
US20090130076A1,COC(=O)c1cc2sc(NC(=O)OC(C)(C)C)nc2c(-c2cccc([N+](=O)[O-])c2)c1OC>>COc1c(CO)cc2sc(NC(=O)OC(C)(C)C)nc2c1-c1cccc([N+](=O)[O-])c1,,C1CCOC1,,[BH4-].[Li+],,test
US20040209948A1,CC1CCCCC1NC(=O)c1cccc2c(S(=O)(=O)NC3CCNCC3)cccc12.CCOC(=O)Cl>>CCOC(=O)N1CCC(NS(=O)(=O)c2cccc3c(C(=O)NC4CCCCC4C)cccc23)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US04956363,CC(Cl)Cl.CCCc1nc(N)nc(N2CCOCC2)n1.O=C(Cl)c1ccccc1>>CCCc1nc(NC(=O)c2ccccc2)nc(N2CCOCC2)n1.Cl,,CC(Cl)Cl,,CCN(CC)CC,,test
US20020137974A1,COc1cccc(Cl)c1.OB(O)c1ccccc1>>COc1cccc(-c2ccccc2)c1,,COCCOC,,[Cs+].[F-],,test
US20130336920A1,CCSc1ccc([N+](=O)[O-])c(-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1>>CCSc1ccc(N)c(-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1,[Pd],CO,,,,test
US20100160303A1,Cc1c(N)cccc1Br.ClCc1ccccc1CCl>>Cc1c(Br)cccc1N1Cc2ccccc2C1,,O,,O=C([O-])[O-].[K+].[K+],,test
US05124478,CO.COc1ccc(C=CC(=O)O)c(OC)c1>>COC(=O)CCc1ccc(OC)cc1OC,,CCOC(C)=O,,[H][H],,test
US20150126498A1,CN.COc1cc([N+](=O)[O-])cnc1Cl>>CNc1ncc([N+](=O)[O-])cc1OC,,CCO,,,,test
US20150225412A1,CC(C)(C)CNC(=O)c1ccc2c(c1)nc(NC(=O)c1ccc(C(F)F)s1)n2C[C@H]1CCCN1.N#CCC(=O)O>>CC(C)(C)CNC(=O)c1ccc2c(c1)nc(NC(=O)c1ccc(C(F)F)s1)n2C[C@H]1CCCN1C(=O)CC#N,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160122342A1,C=CCOc1cc(C)nc(OC)c1C#N>>C=CCOc1cc(C)nc(OC)c1CN,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090264399A1,C[C@@H]1CCCC[C@@H]1Nc1c(C(=O)O)cnc2[nH]ccc12.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>C[C@@H]1CCCC[C@@H]1n1c(=O)[nH]c2cnc3[nH]ccc3c21,,CC(C)(C)O,,CCN(CC)CC,,test
US20120245169A1,BrC(Br)(Br)Br.Cc1ccccc1-n1c(C(C)O)cc2cccc(C)c2c1=O>>Cc1ccccc1-n1c(C(C)Br)cc2cccc(C)c2c1=O,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US06887896B1,CCOC(=O)/C=C(C)/C=C/C=C(/C)c1cc2c(cc1OC)OC(C)(C)C=C2CC>>CCC1=CC(C)(C)Oc2cc(OC)c(/C(C)=C\C=C\C(C)=C\C(=O)O)cc21,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20100227859A1,O=S(=O)(O)Cl.O=[N+]([O-])c1ccc2c(c1)sc1ccccc12>>O=[N+]([O-])c1ccc2c(c1)sc1ccc(S(=O)(=O)O)cc12,,O=C(O)C(F)(F)F,,,,test
US06002008,CC#CC(=O)O.N#Cc1cnc2ccc(N)cc2c1Nc1cccc(C(F)(F)F)c1>>CC#CC(=O)Nc1ccc2ncc(C#N)c(Nc3cccc(C(F)(F)F)c3)c2c1,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20140140956A1,CO.COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCO)c(-c4ccc(S(C)=O)cc4)c3)nc2c1.c1ccncc1>>COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCNC(C)C)c(-c4ccc(S(C)=O)cc4)c3)nc2c1,,CO,ClCCl,CS(=O)(=O)Cl,,test
US20140315888A1,Cc1nc2c3cc(Cl)cnc3nc(O)n2n1.O=P(Cl)(Cl)Cl>>Cc1nc2c3cc(Cl)cnc3nc(Cl)n2n1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20120245181A1,CC1(C)CC(=O)CCO1.Cc1ccc(Br)cc1>>Cc1ccc(C2(O)CCOC(C)(C)C2)cc1,,C1CCOC1,,[Li]CCCC,,test
US20150126449A1,N#Cc1c(F)cccc1-c1nccs1.NN>>Nc1n[nH]c2cccc(-c3nccs3)c12,,CCO,,O,,test
US06413974B1,Clc1nc(Cl)c2ncn(C3CCCC3)c2n1.NCCCCCCCCN>>NCCCCCCCCNc1nc(Cl)nc2c1ncn2C1CCCC1,,CCN(CC)CC,,,,test
US20130059856A1,CN(C)/C=N/C(N)=S.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>CN(C)/C=N/C(=S)NC(c1ccccc1)(c1ccccc1)c1ccccc1,,ClCCl,,,,test
US20060247140A1,C=O.CCCCCCCCCCCCc1ccccc1O.O=C(O)c1ccccc1O>>C=O.CCCCCCCCCCCCc1ccccc1O.O=C(O)c1ccccc1O,,Cc1ccccc1,,N,O,test
US20030191166A1,C=C(CS(C)(=O)=O)C(=O)O>>CC(CS(C)(=O)=O)C(=O)O,[Pd],CO,,,,test
US20150005305A1,O[C@H](CBr)c1ccc(F)cc1>>Fc1ccc([C@H]2CO2)cc1,,COC(C)(C)C,,[Na+].[OH-],,test
US04039551,CN(C)O.ClCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2>>CN(C)Cc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2,,CN(C)C=O,,[H-].[Na+],,test
US20160198708A1,CCOC(=O)C(C#N)c1ncc(Br)cc1Cl>>N#CCc1ncc(Br)cc1Cl,,CS(C)=O,O,[Cl-].[Na+],,test
US20130210858A1,COC(=O)c1ccc(S(=O)(=O)Cl)cc1.NCc1ccc2occc2c1>>COC(=O)c1ccc(S(=O)(=O)NCc2ccc3occc3c2)cc1,,ClCCl,,Cl,,test
US05436359,CC(=O)Cl.COc1c(O)c(CCCCCCCCCCOC(C)=O)c(C)c(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c1OC>>COc1c(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(C)c(CCCCCCCCCCOC(C)=O)c(OC(C)=O)c1OC,,ClCCl,,CCN(CC)CC,,test
US20070123512A1,C=C(C)C(=O)Cl.Cc1cc(N)ccc1[N+](=O)[O-]>>C=C(C)C(=O)Nc1ccc([N+](=O)[O-])c(C)c1,,CC(=O)N(C)C,,O,,test
US05641846,CCCCCC(Br)Br.Oc1ccc(N=Nc2ccccc2)cc1>>BrCCCCCCOc1ccc(N=Nc2ccccc2)cc1,,CC(C)=O,,[I-].[K+],,test
US20100305096A1,CC(C)(C)OC(=O)N1CC(=O)C1.COP(=O)(Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1)OC>>CC(C)(C)OC(=O)N1CC(=Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)C1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20110009454A1,CCCCc1cccc(C#N)c1>>CCCCc1cccc(CN)c1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US07517367B2,COS(=O)(=O)[O-].C[n+]1ccccc1CCOc1ccccc1[N+](=O)[O-]>>COS(=O)(=O)[O-].C[n+]1ccccc1CCOc1ccccc1N,[Pd],O,,[H][H],,test
US04454338,N=C(N)c1ccc2cc(OC(=O)c3ccc(OCc4ccccc4)cc3)ccc2c1>>N=C(N)c1ccc2cc(OC(=O)c3ccc(O)cc3)ccc2c1,[Pd],CN(C)C=O,,CS(=O)(=O)O,,test
US20130143880A1,Cn1c(=O)n(CC(C)(C)C)c2ccc(-c3cccc(O)c3)c(F)c21.N#Cc1ccc(Br)cc1>>Cn1c(=O)n(CC(C)(C)C)c2ccc(-c3cccc(Oc4ccc(C#N)cc4)c3)c(F)c21,[Cu]I,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04328367,CCSCCNC(=O)C1=C(C(=O)Nc2ccc(Cl)cc2F)CCCC1.O=C(OO)c1cccc(Cl)c1>>CCS(=O)CCNC(=O)C1=C(C(=O)Nc2ccc(Cl)cc2F)CCCC1,,ClC(Cl)Cl,,,,test
US04778912,CCCCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCCCCCCCCCCCCCC[N+](C)(C)C)OCc1ccccc1>>CCCCCCCCCCCCCCCCCCOCC(O)COP(=O)([O-])OCCCCCCCCCCCCCC[N+](C)(C)C,[Pd],CC(=O)O,,[H][H],,test
US20120142714A1,CCOC(C)=O.C[C@@H](COc1cnc(-c2nc3ccc(OCC4CC4(F)F)cc3o2)c(F)c1)NC(=O)OC(C)(C)C>>CC(=O)N[C@@H](C)COc1cnc(-c2nc3ccc(OCC4CC4(F)F)cc3o2)c(F)c1,,CCOC(C)=O,,Cl,,test
US06649642B2,CON(C)C(=O)CN(C)Cc1ccccc1.Cl[Mg]CCc1ccccc1>>CN(CC(=O)CCc1ccccc1)Cc1ccccc1,,C1CCOC1,,,,test
US20130150341A1,O=C(O)Cn1nc(-c2ccc(F)cc2)nc1-c1ccc(F)cc1.c1nc2c(s1)CCNCC2>>O=C(Cn1nc(-c2ccc(F)cc2)nc1-c1ccc(F)cc1)N1CCc2ncsc2CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040242890A1,COS(=O)(=O)OC.O=C1CN(c2cccc(I)c2)C(=O)N1>>CN1C(=O)CN(c2cccc(I)c2)C1=O,,O,,[K+].[OH-],,test
US20020037888A1,COc1cccc(C2CCCCNC2=O)c1>>O=C1NCCCCC1c1cccc(O)c1,,ClCCl,,BrB(Br)Br,,test
US20150315209A1,CCOC(=O)C1CCNCC1.Fc1cnccc1-n1cc(Br)cn1>>CCOC(=O)C1CCN(c2cnccc2-n2cc(Br)cn2)CC1,,CN1CCCC1=O,,,,test
US20090281086A1,CC(C)(C)OC(=O)N1CCCNCC1.CC(O)c1ccc(F)c(C(=O)O)c1>>CC(O)c1ccc(F)c(C(=O)N2CCCN(C(=O)OC(C)(C)C)CC2)c1,,ClCCl,,CCN(CC)CC,,test
US20030083238A1,COCCCCCOC1CCN(C(=O)OC(C)(C)C)CC1>>COCCCCCOC1CCNCC1,,CCOC(C)=O,,Cl,,test
US20060100246A1,COC(=O)c1sccc1OCc1ccccc1>>O=C(O)c1sccc1OCc1ccccc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20060160857A1,Cc1cc(NC(=O)c2nc(C)sc2N)ccn1.FC(F)(F)c1cncc(Br)c1>>Cc1cc(NC(=O)c2nc(C)sc2Nc2cncc(C(F)(F)F)c2)ccn1,,C1CCOC1,C1COCCO1,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20060111429A1,C1CCOC1.CC(C)OC(=O)N=NC(=O)OC(C)C.O=C(O)CS.OCC1CCC1>>CC(C)(C)OC(=O)N1CC[C@H](NCC2CCC2)C1,,C1CCOC1,,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100029609A1,CCOc1cc(OC)c(CN(CCCOC)C(=O)c2ccc(-c3cccc(NS(=O)(=O)c4cc(C)c(Cl)cc4C)c3)cc2)c(OC)c1>>COCCCNC(=O)c1ccc(-c2cccc(NS(=O)(=O)c3cc(C)c(Cl)cc3C)c2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080139576A1,CCCCCN.COc1ccc(CN2C(=O)CN(c3cccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)O)c3)S2(=O)=O)cc1>>CCCCCNC(=O)[C@H](Cc1cccc(N2CC(=O)N(Cc3ccc(OC)cc3)S2(=O)=O)c1)NC(=O)OC(C)(C)C,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20140162983A1,Nc1cccc(O)c1.Nc1ncnc(Cl)c1Cl>>Nc1cccc(Oc2ncnc(N)c2Cl)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060235030A1,CN(C)CCNc1nc(Cl)c2c(n1)N(c1c(F)cccc1F)C(=O)NC2.Cc1ccc(C(=O)O)cc1B1OC(C)(C)C(C)(C)O1>>Cc1ccc(C(=O)O)cc1-c1nc(NCCN(C)C)nc2c1CNC(=O)N2c1c(F)cccc1F,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20060063762A1,CCN(CC)C(=O)c1cccc2c(C[C@@H](C)N3C[C@@H](c4cccc(Cl)c4)OC3=O)c[nH]c12.CI>>CCN(CC)C(=O)c1cccc2c(C[C@@H](C)N3C[C@@H](c4cccc(Cl)c4)OC3=O)cn(C)c12,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120289698A1,O=C(Cl)Cc1ccc(F)cc1.O=C1N[C@@H](Cc2ccccc2)CO1>>O=C(Cc1ccc(F)cc1)N1C(=O)OC[C@@H]1Cc1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US20110105766A1,O=[N+]([O-])c1ccccc1Cl.OB(O)c1cc(F)c(F)c(F)c1>>O=[N+]([O-])c1ccccc1-c1cc(F)c(F)c(F)c1,Cl[Pd]Cl,C1CCOC1,COC(C)(C)C,[Na+].[OH-],,test
US04463173,CCI.O=C(O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)n1>>CCOC(=O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)n1,,C1CCOC1,,O,,test
US20090227588A1,COC(=O)c1cccc(N2CCOCC2)c1>>O=C(O)c1cccc(N2CCOCC2)c1,,C1COCCO1,O,[Li+].[OH-],,test
US20160068525A1,ClCCN1CCCCC1.Oc1ccc(-c2ccn3c(-c4ccncc4)cnc3c2)cc1>>c1cc(-c2cnc3cc(-c4ccc(OCCN5CCCCC5)cc4)ccn23)ccn1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20140045862A1,C1CCC2OC2C1.CCn1cccn1>>CCn1nccc1[C@H]1CCCC[C@@H]1O,,C1CCOC1,,[Li]CCCC,,test
US20050215547A1,COc1ccc(COc2cccc(OCC3CC3)c2-c2cc(C3CCCN(C(=O)OC(C)(C)C)C3)c3c(n2)NC(=O)OC3)cc1.Cl>>Cl.O=C1Nc2nc(-c3c(O)cccc3OCC3CC3)cc(C3CCCNC3)c2CO1,,C1COCCO1,,,,test
US20040127574A1,NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccc(F)cc1.O=S(=O)(Cl)c1cccc2ccccc12>>O=S(=O)(NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccc(F)cc1)c1cccc2ccccc12,,CCOC(C)=O,O,Cl,O=C([O-])O.[Na+],test
US20080221195A1,C#Cc1ccccc1.CCCOc1ccc(I)cc1C(=O)OC>>CCCOc1ccc(C#Cc2ccccc2)cc1C(=O)OC,[Cu]I,CCNCC,,,,test
US20140135318A1,CCCCN(CCCC)C(=O)c1nn(-c2ccc(C(=O)NS(=O)(=O)c3ccc4ccccc4c3)cc2C(=O)N2CCc3ccccc3C2)c(CC(=O)O)c1Cl.NS(=O)(=O)C1CC1>>CCCCN(CCCC)C(=O)c1nn(-c2ccc(C(=O)NS(=O)(=O)c3ccc4ccccc4c3)cc2C(=O)N2CCc3ccccc3C2)c(CC(=O)NS(=O)(=O)C2CC2)c1Cl,,C1CCOC1,CCOC(C)=O,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US20020193367A1,CC(C)(C)OC(=O)CC(=O)c1cccc(-c2nnc(CCOC3CCCCO3)s2)c1.CN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1Cl>>CN(C)c1cc2c(cc1Cl)NC(=O)CC(c1cccc(-c3nnc(CCO)s3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US05244908,NCCSc1cccc2nccn12.O=C1OC(=O)c2ccccc21>>O=C(O)c1ccccc1C(=O)NCCSc1cccc2nccn12,,ClC(Cl)Cl,,,,test
US20070197627A1,C[C@H](Cc1cc(C#N)c2c(c1)CCN2CCCOC(=O)c1ccccc1)NCCOc1ccccc1OCC(F)(F)F.O=C(O)C(=O)O>>C[C@H](Cc1cc(C#N)c2c(c1)CCN2CCCOC(=O)c1ccccc1)NCCOc1ccccc1OCC(F)(F)F.O=C(O)C(=O)O,,CC(C)O,,O,O,test
US20100210622A1,CCOC(=O)c1nc(N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)sc1CCCI.N#Cc1cscc1-c1ccc(O)cc1>>N#Cc1cscc1-c1ccc(OCCCc2sc(N3CCc4cccc(C(=O)Nc5nc6ccccc6s5)c4C3)nc2C(=O)O)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20070060607A1,Cl.Nc1ncc(C(=O)NCCCO)c2scc(COc3cccc(NC(=O)c4ccc(Cl)cc4)c3)c12>>Cl.Nc1ncc(C(=O)NCCCO)c2scc(COc3cccc(NC(=O)c4ccc(Cl)cc4)c3)c12,,CCOCC,CO,,,test
US20040110749A1,CC1(C)CC(SCc2c(Cl)nn(C(F)F)c2C(F)(F)F)=NO1.O=C(OO)c1cccc(Cl)c1>>CC1(C)CC(S(=O)(=O)Cc2c(Cl)nn(C(F)F)c2C(F)(F)F)=NO1,,ClC(Cl)Cl,,O,,test
US20070213392A1,CCOC(=O)c1cc2ccc(CO)cc2s1>>CCOC(=O)c1cc2ccc(C=O)cc2s1,O=[Mn]=O,ClCCl,,,,test
US20160152570A1,CCO[C@@H](Cc1ccc(OCC(=O)c2cccc(OC)c2)cc1)C(=O)N(C)OC>>CCO[C@@H](Cc1ccc(OC[C@H](O)c2cccc(OC)c2)cc1)C(=O)N(C)OC,,CN(C)C=O,,,,test
US20110130380A1,C=C[C@H]1CN(C(=O)OCc2ccccc2)C[C@H]1O.CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1>>C=C[C@H]1CN(C(=O)OCc2ccccc2)C[C@H]1O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,ClCCl,,c1c[nH]cn1,,test
US20060142317A1,CN1CCc2c(sc3ncn(CCO)c(=O)c23)C1.O=S(Cl)Cl>>CN1CCc2c(sc3ncn(CCCl)c(=O)c23)C1,,ClCCCl,,,,test
US20080214621A1,COC(=O)CCCOc1ccc2cc(CC3CCN(C4CCCCC4)C3=O)ccc2c1>>O=C(O)CCCOc1ccc2cc(CC3CCN(C4CCCCC4)C3=O)ccc2c1,,CCO,,[K+].[OH-],,test
US06956049B1,CC(N)=S.O=C(C#Cc1ccccc1)CCl>>Cc1nc(C#Cc2ccccc2)cs1,,CC#N,,CCCCCC,CCOC(C)=O,test
US20080269193A1,CC(C)(C)OC(=O)NCC(=O)O.Cc1cn(-c2cc(F)c(C(N)=O)c(N[C@H]3CCC[C@@H]3O)c2)c2c1C(=O)CC(C)(C)C2>>Cc1cn(-c2cc(F)c(C(N)=O)c(N[C@H]3CCC[C@@H]3OC(=O)CNC(=O)OC(C)(C)C)c2)c2c1C(=O)CC(C)(C)C2,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US06545033B1,C[Mg]Br.O=C1c2cn(-c3c(Cl)cc(C(F)(F)F)cc3Cl)nc2C(F)C1F>>CC1(O)c2cn(-c3c(Cl)cc(C(F)(F)F)cc3Cl)nc2C(F)C1F,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20070281933A1,NC(=O)c1cc(-c2cccc(F)c2)cc2c(C3CCNCC3)n[nH]c12.O=S(=O)(Cl)CCCCl>>NC(=O)c1cc(-c2cccc(F)c2)cc2c(C3CCN(S(=O)(=O)CCCCl)CC3)n[nH]c12,,CN(C)C=O,,CCN(CC)CC,,test
US20090042876A1,CCO.N.O=C(O)c1c[nH]c2c(=O)[nH]c3ccc(S(=O)(=O)Cl)cc3c12>>CCC(=O)[O-].NS(=O)(=O)c1ccc2[nH]c(=O)c3[nH]ccc3c2c1,,CCO,,O=S(Cl)Cl,,test
US20080021217A1,Br.CC(C)(C)OC(=O)NCc1nc(-c2ccncc2)nn1CCBr>>Br.NCc1nc(-c2ccncc2)nn1CCBr,,CC(=O)O,,,,test
US20160251348A1,CC(C)(C)OC(=O)N1CCN(C(=N)N)CC1.CCOC(=O)c1cccnc1Cl>>CC(C)(C)OC(=O)N1CCN(c2nc3ncccc3c(=O)[nH]2)CC1,,CN(C)C=O,O,Cl,CC(C)(C)[O-].[K+],test
US05134128,OCCCC#Cc1ccccn1>>OCCCCCC1CCCCN1,[Rh],,,,,test
US20100311769A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=c1[nH]c2ccccc2c(=O)n1CCCNCCCCNCCCn1c(=O)[nH]c2ccccc2c1=O>>CC(C)(C)OC(=O)N(CCCCNCCCn1c(=O)[nH]c2ccccc2c1=O)CCCn1c(=O)[nH]c2ccccc2c1=O,,c1ccncc1,,,,test
US20120184735A1,COc1c(N)cc(C(C)(C)C)cc1CO.O=C(Cl)OCC(Cl)(Cl)Cl>>COc1c(CO)cc(C(C)(C)C)cc1NC(=O)OCC(Cl)(Cl)Cl,,C1CCOC1,,CCN(C(C)C)C(C)C,O,test
US20100317568A1,Nc1ccc(S(=O)(=O)C(F)(F)F)cc1.O=C(CCC(=O)c1ccc(Br)cc1)c1ccc(Br)cc1>>O=S(=O)(c1ccc(-n2c(-c3ccc(Br)cc3)ccc2-c2ccc(Br)cc2)cc1)C(F)(F)F,Cl[Ti](Cl)(Cl)Cl,Cc1ccccc1,,,,test
US20030166650A1,COC(=O)N1CCc2ccc(C(C)=O)cc2C1.[NH4+].[OH-]>>COC(=O)N1CCc2ccc(C(C)=NO)cc2C1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20110086834A1,CC(=O)c1ncc(C=NO)s1>>CC(=O)c1ncc(C#N)s1,,CC(=O)OC(C)=O,,,,test
US03947466,O=C(c1ccccc1)c1cc([N+](=O)[O-])ccc1-n1c(CN2C(=O)c3ccccc3C2=O)nnc1CN1C(=O)c2ccccc2C1=O>>NCc1nnc2n1-c1ccc([N+](=O)[O-])cc1C(c1ccccc1)=NC2,,CCO,,NN,O,test
US20090186868A1,C=C[C@H]1[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)C(=O)N1c1ccc(OC)cc1>>C=C[C@H]1[C@@H](O)C(=O)N1c1ccc(OC)cc1,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20070161797A1,NC(=O)c1cccnc1.[O-]Cl>>O=C(NCl)c1cccnc1,,O,,[Na+].[OH-],,test
US20090131433A1,C1CCNC1.CCOc1cc(C=O)ccc1O>>CCOc1cc(CN2CCCC2)ccc1O,,ClCCl,O,[Na+].[OH-],,test
US20050288290A1,O=[N+]([O-])c1ccc(Oc2ncnn3ccc(Cl)c23)c(F)c1>>Nc1ccc(Oc2ncnn3ccc(Cl)c23)c(F)c1,[Zn],C1CCOC1,,CO,[Cl-].[NH4+],test
US04997947,C1COCCN1.CC(=O)c1ccsc1>>C=C(c1ccsc1)N1CCOCC1,Cl[Ti](Cl)(Cl)Cl,C1CCCCC1,,,,test
US20100273819A1,C=C(N=Cc1cc(F)ccc1C)O[Si](C)(C)C.COC(=O)C(C)(C)Oc1cc(F)c(Cl)cc1/C=C1\C(=O)N(C(=O)OC(C)(C)C)c2cc(Cl)ccc21>>COC(=O)C(C)(C)Oc1cc(F)c(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)Nc1cc(Cl)ccc12,,Cc1ccccc1,,,,test
US04683241,CC(C)(C(=O)Cl)C(=O)Cl.O.O=C(c1ccccc1)c1ccc(O)cc1>>CC(C)(C(=O)O)C(=O)Oc1ccc(C(=O)c2ccccc2)cc1,,ClCCl,c1ccncc1,CCOC(C)=O,,test
US20040235905A1,OC(COc1cc(OCc2ccccc2)ccc1OCc1ccccc1)c1ccccc1>>Oc1ccc(O)c(OCC(O)c2ccccc2)c1,[Pd],CCO,,,,test
US20150191482A1,CCN(CC)CC.O=C1N[C@@H]2CC[C@H]1CNC2.OB(O)c1cnc(Cl)nc1>>CC[NH+](CC)CC.O=C1NC2CCC1CN(c1ncc(B(O)O)cn1)C2.[Cl-],,CCO,,,,test
US20130116281A1,Cc1ccc2cc(C#C[Si](C)(C)C)ccc2n1>>C#Cc1ccc2nc(C)ccc2c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20100273837A1,CCOC(=O)c1nc(-c2ccc(Cl)cc2OC)ns1>>COc1cc(Cl)ccc1-c1nsc(CO)n1,,CCO,,[BH4-].[Na+],,test
US05677309,Clc1nc(NNc2ccccc2)c2ccccc2n1.S=C(Cl)Cl>>S=c1n(-c2ccccc2)nc2c3ccccc3nc(Cl)n12,,C1CCOC1,,CCN(CC)CC,O,test
US20050267093A1,Clc1cc(Cl)c(C#C[Si](c2ccccc2)(c2ccccc2)c2ccccc2)c(Cl)c1>>C#Cc1c(Cl)cc(Cl)cc1Cl,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130253194A1,CN(CCNc1ccn2ncc(Br)c2n1)C(=O)OC(C)(C)C>>CNCCNc1ccn2ncc(Br)c2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140288123A1,CCN=C=NCCCN(C)C.C[C@H](Oc1cccc(Br)c1)c1ccc(C(=O)O)cc1.Cc1cc(C)c(CN)c(O)n1.On1nnc2ccccc21>>Cc1cc(C)c(CNC(=O)c2ccc([C@H](C)Oc3cccc(-c4ccc(N)nc4)c3)cc2)c(O)n1,,CCN(CC)CC,ClCCl,Cl,,test
US05053338,CC(CC(=O)O)C(=O)c1ccc(O)cc1.NN>>CC1CC(=O)NN=C1c1ccc(O)cc1,,CC(C)O,,O,,test
US20060128964A1,Cc1c(OCC(F)(F)F)ccnc1CSc1nc2ccccc2[nH]1.OO>>Cc1c(OCC(F)(F)F)ccnc1C[S+]([O-])c1nc2ccccc2[nH]1,,CC(C)O,,O,,test
US06174877B1,C1CO1.c1ccc(-n2ccnc2)cc1>>OCCc1nccn1-c1ccccc1,,C1CCOC1,CCCCCC,O,[Li]CCCC,test
US20080194520A1,CC(=O)OC=O.CCCC#CC(CS(=O)(=O)N1CCN(c2ccccn2)CC1)NO>>CCCC#CC(CS(=O)(=O)N1CCN(c2ccccn2)CC1)N(O)C=O,,C1CCOC1,,,,test
US20140315888A1,Cc1cnc2nc(N3CC(N(C)C(=O)OC(C)(C)C)C3)c3nncn3c2c1>>CNC1CN(c2nc3ncc(C)cc3n3cnnc23)C1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110319413A1,Cc1ccc(S(=O)(=O)OCCCC2CCN(c3ccc([N+](=O)[O-])cc3)CC2)cc1.c1nc[nH]n1>>O=[N+]([O-])c1ccc(N2CCC(CCCn3cncn3)CC2)cc1,,CC#N,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090036492A1,BrP(Br)Br.CN(C)C=O.O=C1CCc2ccc(F)c(F)c2C1>>O=CC1=C(Br)CCc2ccc(F)c(F)c21,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20070043065A1,C1CCNC1.Cc1ccc(S(=O)(=O)OCC(C)(O)COc2ccc3ncn(-c4cc(C(=O)NC5CC5)ccc4C)c(=O)c3c2)cc1>>Cc1ccc(C(=O)NC2CC2)cc1-n1cnc2ccc(OCC(C)(O)CN3CCCC3)cc2c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040127574A1,COCc1ccc(C(=O)OC)c2ccccc12>>COCc1ccc(C(=O)O)c2ccccc12,,CO,,Cl,[Na+].[OH-],test
US20040121964A1,CC1(NC(=O)OCc2ccccc2)CCN(C(=O)c2ccncc2)CC1>>CC1(N)CCN(C(=O)c2ccncc2)CC1,,CC#N,,C[Si](C)(C)I,,test
US20070049618A1,COc1ccc([N+](=O)[O-])c(I)c1.Oc1ccccc1>>COc1ccc([N+](=O)[O-])c(Oc2ccccc2)c1,Br[Cu]Br,c1ccncc1,,[H-].[Na+],,test
US05262412,CCCCc1nn(-c2cc([N+](=O)[O-])ccc2Cl)c(C(=O)OCC)c1Cc1ccc(-c2ccccc2S(N)(=O)=O)cc1.O=C(O)c1ccccc1Cl>>CCCCc1nn(-c2cc([N+](=O)[O-])ccc2Cl)c(C(=O)OCC)c1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)cc1,,C1CCOC1,,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US06045776,CC(Br)C(=O)Cl.NCCCCCCCCCCC(=O)O>>CC(Br)C(=O)NCCCCCCCCCCC(=O)O,,ClCCl,,CCN(CC)CC,Cl,test
US20130005707A1,CC(C)(C)OC(=O)N1C(=O)C(C)(C)c2ccc([N+](=O)[O-])cc21>>CC(C)(C)OC(=O)N1C(=O)C(C)(C)c2ccc(N)cc21,[Pd],CO,,CCOC(C)=O,[H][H],test
US20100087452A1,CO.CS(=O)(=O)c1cc(-c2ccc(C(F)(F)F)cn2)n2ncnc2n1>>COc1cc(-c2ccc(C(F)(F)F)cn2)n2ncnc2n1,,O,,C[O-].[Na+],,test
US20160220570A1,COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(Cl)c2n1.OB(O)c1cncnc1>>COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(-c3cncnc3)c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20130065880A1,Cc1cccc(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)O)c[nH]4)c3)cc2)c1.OCC(CO)(CO)CO>>Cc1cccc(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)OCC(CO)(CO)CO)c[nH]4)c3)cc2)c1,CN(C)c1ccncc1,C1CCOC1,,CCN=C=NCCCN(C)C,Cl,test
US20140128390A1,CCc1ccc(S(=O)(=O)NC2CCN(c3ncnc4c3cc(-c3cnn(C)c3)n4S(=O)(=O)c3ccccc3)CC2)cc1>>CCc1ccc(S(=O)(=O)NC2CCN(c3ncnc4[nH]c(-c5cnn(C)c5)cc34)CC2)cc1,,C1CCOC1,CO,[K+].[OH-],,test
US20060116388A1,CCC(=O)Cl.NCc1ccccc1C(=O)O>>CCC(=O)Nc1cccc(C)c1C(=O)O,,CN(C)C=O,,O,O,test
US05246948,Nc1ccccc1C(=O)NCCCSc1ccncc1.S=C(n1ccnc1)n1ccnc1>>O=c1c2ccccc2[nH]c(=S)n1CCCSc1ccncc1,,C1CCOC1,,,,test
US20160075710A1,CC(=O)c1cc(=O)n(CC2CC2)nc1-c1ccccc1>>CC(O)c1cc(=O)n(CC2CC2)nc1-c1ccccc1,,C1CCOC1,CO,,,test
US20080255083A1,CC(=O)NC1CCNCC1.O=c1cc(OCc2ccsc2)ccn1CCc1ccc(CCl)cc1>>CC(=O)NC1CCN(Cc2ccc(CCn3ccc(OCc4ccsc4)cc3=O)cc2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070043061A1,CC(=O)Cl.Nc1nonc1-c1nc2ccccc2n1CC(=O)c1ccc(Cl)cc1>>CC(=O)Nc1nonc1-c1nc2ccccc2n1CC(=O)c1ccc(Cl)cc1,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,c1ccncc1,,test
US20120108585A1,Nc1nccs1.O=C(O)c1ccnc2sc(-c3cccc(C(F)(F)F)c3)nc12>>O=C(Nc1nccs1)c1ccnc2sc(-c3cccc(C(F)(F)F)c3)nc12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05286869,COC(=O)C1=C(C)NC(C)=C(C(=O)O)C1c1cccc([N+](=O)[O-])c1.OC/C=C/c1ccc(Cn2cnnn2)cc1>>COC(=O)C1=C(C)NC(C)=C(C(=O)OC/C=C/c2ccc(Cn3cnnn3)cc2)C1c1cccc([N+](=O)[O-])c1,,Cc1ccccc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20110301031A1,BrCC1CC1.CON1CCC2(CC1)NC(=O)C(c1c(C)cc(C)cc1C)=C2OCc1ccccc1>>CON1CCC2(CC1)C(OCc1ccccc1)=C(c1c(C)cc(C)cc1C)C(=O)N2CC1CC1,,C1COCCO1,,CC(C)(C)[O-].[K+],,test
US20130005574A1,CC1(C)OB(c2ccc([Si](C)(C)C)c(F)c2F)OC1(C)C.COC(=O)c1nc(Cl)c(F)c(N)c1OC>>COC(=O)c1nc(-c2ccc([Si](C)(C)C)c(F)c2F)c(F)c(N)c1OC,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,O,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US20080153812A1,CC1CNCC(C)N1.CCOC(=O)c1ccc(F)cc1>>CCOC(=O)c1ccc(N2CC(C)NC(C)C2)cc1,,CS(C)=O,,,,test
US20100215618A1,CC(C)(C)OC(=O)N[C@H](C(=O)O)c1ccccc1.O=C(Nc1ccc(CN2CCS(=O)(=O)CC2)cc1)c1ccc(-c2ccc(-c3cnc([C@@H]4CCCN4)[nH]3)cc2)cc1>>CC(C)(C)OC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc(-c3ccc(C(=O)Nc4ccc(CN5CCS(=O)(=O)CC5)cc4)cc3)cc2)[nH]1)c1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US03931168,O=C(O)CC(=O)O.O=Cc1ccc(F)c(Cl)c1>>O=C(O)C=Cc1ccc(F)c(Cl)c1,,c1ccncc1,,C1CCNCC1,Cl,test
US20030078251A1,CCOC(=O)CBr.COc1cc([N+](=O)[O-])cc(C=O)c1O>>CCOC(=O)c1cc2cc([N+](=O)[O-])cc(OC)c2o1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20080292585A1,CCCCCCCCOC(=O)Cl.CN(C)CCN1C(=O)c2cccc3cc4cccc(N)c4c(c23)C1=O>>CCCCCCCCOC(=O)Nc1cccc2cc3cccc4c3c(c12)C(=O)N(CCN(C)C)C4=O,,ClCCl,,CCN(CC)CC,CO,test
US20020156283A1,C1CCNC1.COC(OC)N(C)C.O=C(CCCN1CCC(c2csc3cc(F)ccc23)CC1)c1ccc(F)cc1>>O=C(C(=CN1CCCC1)CCN1CCC(c2csc3cc(F)ccc23)CC1)c1ccc(F)cc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20090099190A1,CC(C)(C)Nc1cc(Cl)ncc1C=O.Nc1ccc(F)c([N+](=O)[O-])c1>>CC(C)(C)Nc1cc(Cl)ncc1CNc1ccc(F)c([N+](=O)[O-])c1,,CC(=O)O,,[Na+].[OH-],,test
US20140275007A1,CC(C)(C)OC(=O)CO/N=C(\C(=O)Cl)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1.CC1(C)[C@H](N)C(=O)N1O>>CC(C)(C)OC(=O)CO/N=C(\C(=O)N[C@@H]1C(=O)N(O)C1(C)C)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1,,C1CCOC1,,CCN(CC)CC,,test
US04976887,CCCCCCC(C)Br.O=C1C(O)=CC=C2C1=Cc1cc(O)ccc12>>CCCCCCC(C)Oc1ccc2c(c1)C=C1C(=O)C(O)=CC=C12,,CCO,,[K+].[OH-],,test
US20140349990A1,Cc1c(C(Nc2cc(F)c(=O)n(C)c2)c2ccc(Cl)cc2)c(C(=O)O)nn1C>>Cc1c2c(nn1C)C(=O)N(c1cc(F)c(=O)n(C)c1)C2c1ccc(Cl)cc1,,CO,ClCCl,,,test
US20110245224A1,CCC1CO1.NCc1ccccc1>>CCC(O)CNCc1ccccc1,,CCO,,,,test
US20100125062A1,OC1C=C(c2cccnc2F)CC1>>OC1CCC(c2cccnc2F)C1,[Pd],C1CCOC1,,,,test
US04182775,Cc1ccc(CNC(=O)c2cc(Cl)ccc2Cl)cc1C(=O)O>>Cc1ccc(CNC(=O)c2cccc(Cl)c2)cc1C(=O)O,,CO,,,,test
US20080139558A1,ClCc1ccco1.Nc1ccccc1>>c1ccc(NCc2ccco2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040152893A1,CN(C)CCOc1cc(N)ccc1Cl.N#Cc1c(Cl)cccc1Oc1ccc(S(=O)(=O)Cl)cc1>>CN(C)CCOc1cc(NS(=O)(=O)c2ccc(Oc3cccc(Cl)c3C#N)cc2)ccc1Cl,,ClC(Cl)Cl,,,,test
US20100311747A1,CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C#N.CCN(CC)S(F)(F)F>>CC(C)(C)OC(=O)N1C[C@@H](F)C[C@H]1C#N,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20150018335A1,CN(C)C(=O)c1cc(-c2ccccc2)ccc1CN1CCNCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OC(C(F)(F)F)C(F)(F)F>>CN(C)C(=O)c1cc(-c2ccccc2)ccc1CN1CCN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC1,,ClCCl,O,CCN(C(C)C)C(C)C,,test
US20160175289A1,CC(F)(CO)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(F)(CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C)COS(=O)(=O)C(F)(F)F,,ClCCl,,,,test
US20150152102A1,CCOC(=O)CC(=O)C(F)(F)F.Nc1cc(C2CCN(c3ccccc3)CC2)n[nH]1>>O=C1CC(O)(C(F)(F)F)c2c(C3CCN(c4ccccc4)CC3)n[nH]c2N1,,CC(=O)O,,O=C([O-])O.[Na+],,test
US05055579,CCOS(=O)(=O)c1ccc(C)cc1.Cc1nc2ccccc2s1>>CC[n+]1c(C)sc2ccccc21.Cc1ccc(S(=O)(=O)O)cc1,,CC(C)=O,,,,test
US20020025959A1,Nc1cc(CN2CCOCC2)cc2c(O)c(C(=O)NCc3ccc(Cl)cc3)cnc12.O=C(CBr)OC(=O)CBr>>O=C1Cn2cc(C(=O)NCc3ccc(Cl)cc3)c(=O)c3cc(CN4CCOCC4)cc(c32)N1,,CN(C)C=O,,CCN(CC)CC,CO,test
US06127548,CCCCc1ncc[nH]1.CN(C)S(=O)(=O)Cl>>CCCCc1nccn1S(=O)(=O)N(C)C,,O,,CCN(CC)CC,ClCCl,test
US20090036492A1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.O=Cc1ccc(NS(=O)(=O)c2ccc(Cl)cc2Cl)cc1>>COc1cc(O)c2c(c1C(=O)NCc1ccc(NS(=O)(=O)c3ccc(Cl)cc3Cl)cc1)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20070185079A1,COc1ccc2nc(N[C@H]3CC[C@H](NC(=O)OC(C)(C)C)C3)cc(C)c2c1>>COc1ccc2nc(N[C@H]3CC[C@H](N)C3)cc(C)c2c1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20160229804A1,Cc1ncc(N)c(-c2ccccc2)n1.O=C(Cl)Oc1ccccc1>>Cc1ncc(NC(=O)Oc2ccccc2)c(-c2ccccc2)n1,,ClCCl,O,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20160068532A1,C[C@@H](NCc1cc2c(Cl)nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c2cc1[N+](=O)[O-])c1ccccc1>>C[C@@H](NCc1cc2c(Cl)nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c2cc1N)c1ccccc1,[Zn],CC(=O)O,,,,test
US04096265,CCCCCC(C)C(C)c1cc(O)c2c(c1)OC(C)(C)C1=C2CN(C#N)CC1.CI>>CCCCCC(C)C(C)c1cc(OC)c2c(c1)OC(C)(C)C1=C2CN(C#N)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100197651A1,COc1cn(-c2ccc(I)cc2F)nc(-c2ccnn2-c2ccccc2)c1=O.O=C1NCC2(CC2)O1>>COc1cn(-c2ccc(N3CC4(CC4)OC3=O)cc2F)nc(-c2ccnn2-c2ccccc2)c1=O,[Cu]I,C1COCCO1,CCOC(C)=O,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20110028447A1,COC(=O)c1n[nH]c2ccccc12.Cc1cc(CCl)no1>>COC(=O)c1nn(Cc2cc(C)on2)c2ccccc12,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20040039064A1,CC(C)(C)OC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CO.O=C(Cl)c1ccccc1>>CC(C)(C)OC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)COC(=O)c1ccccc1,,ClCCl,,,,test
US20040132727A1,CC(C)(C)c1ccc(SCCCO)cc1.COc1cc2nccc(Oc3cc(C)c(N)cc3C)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3cc(C)c(NC(=O)OCCCSc4ccc(C(C)(C)C)cc4)cc3C)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20150057271A1,COc1cc(C#N)ccc1N1CCOc2ccc(F)cc21.O=S(=O)(O)Cl>>COc1cc(C#N)ccc1N1CCOc2cc(S(=O)(=O)Cl)c(F)cc21,,ClCCl,,,,test
US04151295,CCOCC(=O)Cl.COCC(C)Nc1c(C)cccc1C>>CCOCC(=O)N(c1c(C)cccc1C)C(C)COC,,Cc1ccccc1,,,,test
US20070037794A1,CON(C)C(=O)c1ccnc(N)c1.CS(=O)(=O)Cl>>CON(C)C(=O)c1ccnc(NS(C)(=O)=O)c1,,c1ccncc1,,,,test
US07399759B2,CCCS.O=c1nc(-c2cccc(CS(=O)(=O)[O-])n2)sc2ccccc12>>CCCSCc1cccc(-c2nc(=O)c3ccccc3s2)n1,,CN(C)C=O,O,CCOC(C)=O,[H-].[Na+],test
US20120035132A1,NC(=O)c1ccc(O)nc1O.O=C1CCC(=O)N1I>>NC(=O)c1cc(I)c(O)nc1O,,ClCCl,,,,test
US20120245136A1,CC(C)(C)OC(=O)N1CCC2(C=C(OS(=O)(=O)C(F)(F)F)c3ccccc3O2)CC1.CN(C)C=O.CO>>COC(=O)C1=CC2(CCN(C(=O)OC(C)(C)C)CC2)Oc2ccccc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,CO,CCN(C(C)C)C(C)C,,test
US20130237533A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)C(CN)NC(=O)OCc1ccccc1>>CC(C)C(CNC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1,,C1CCOC1,,CCOC(C)=O,[Na+].[OH-],test
US20090275574A1,O=C(Cl)CBr.O=C(OCc1ccccc1)N1CCC(N[C@H]2CC3(CC[C@@H]2O)OCCO3)CC1>>O=C(OCc1ccccc1)N1CCC(N(C(=O)CBr)[C@H]2CC3(CC[C@@H]2O)OCCO3)CC1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US05085689,CCCCCCCCCCCCCCCC(=O)C1C(=O)CC(C=O)CC1=O.NOS(=O)(=O)O>>CCCCCCCCCCCCCCCC(=O)C1C(=O)CC(C#N)CC1=O,,O,,,,test
US20040014802A1,CCCC(=O)Nc1nn(COCC[Si](C)(C)C)c2cc(Cl)c(B3OC(C)(C)C(C)(C)O3)cc12.O=[N+]([O-])c1ccc(Br)cc1>>CCCC(=O)Nc1nn(COCC[Si](C)(C)C)c2cc(Cl)c(-c3ccc([N+](=O)[O-])cc3)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US04354027,CCC(=O)Cl.COc1ccc2c(c1)nc(NN)c(=O)n2C>>CCC(=O)NNc1nc2cc(OC)ccc2n(C)c1=O,,C1COCCO1,,CCN(CC)CC,,test
US20110245264A1,COc1cc(OCc2ccccc2)ccc1[C@H](CO)NC(=O)OCc1ccccc1>>COc1cc(O)ccc1[C@@H](N)CO,[Pd],CCOC(C)=O,CO,,,test
US20160038504A1,COC(=O)c1cccc(C(C)(C)S(C)(=O)=O)c1>>CC(C)(c1cccc(C(=O)O)c1)S(C)(=O)=O,,O,,C1CCOC1,[Li+].[OH-],test
US20050277662A1,COC(=O)c1cc2c(CN3CC[C@@H]4C(=O)NC[C@@H]4C3)cn(Cc3ccc(F)cc3F)c2cn1.NO>>O=C(NO)c1cc2c(CN3CC[C@@H]4C(=O)NC[C@@H]4C3)cn(Cc3ccc(F)cc3F)c2cn1,,CO,,[Na+].[OH-],,test
US20150376136A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)C(C)(C#N)C1CCCCC1>>CCOC(=O)C(C)(CNC(=O)OC(C)(C)C)C1CCCCC1,Cl[Ni]Cl,CCO,CCO,[BH4-].[Na+],,test
US06716856B1,Cc1nn(-c2ccccn2)c2c1C(=O)CC(C)(C)C2.O=C1CCC(=O)N1Br>>Cc1nn(-c2ccccn2)c2c1C(=O)CC(C)(C)C2Br,,ClC(Cl)Cl,,,,test
US20030105056A1,O=C(Nc1ncnc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1)c1ccccc1.O=C1NC(=O)c2ccccc21>>O=C(Nc1ncnc2c1ncn2[C@H]1C[C@H](O)[C@@H](CN2C(=O)c3ccccc3C2=O)O1)c1ccccc1,,C1CCOC1,ClCCl,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020111358A1,C[O-].Cc1ccccc1.O=Cc1ccccc1O>>O=C1OCCC1=Cc1ccccc1O,,Cc1ccccc1,,O=S(=O)(O)O,,test
US20100310512A1,COC(=O)NC(C(=O)O)C(C)C.COC(=O)NC(CCC(F)(F)F)C(=O)N1CCCC1c1ncc(-c2ccc(-c3ccc(-c4cnc(C5CCCN5)[nH]4)cc3)cc2)[nH]1>>COC(=O)NC(CCC(F)(F)F)C(=O)N1CCCC1c1ncc(-c2ccc(-c3ccc(-c4cnc(C5CCCN5C(=O)C(NC(=O)OC)C(C)C)[nH]4)cc3)cc2)[nH]1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05952362,BrCc1ccccc1.N#CCOc1ccc(O)c([N+](=O)[O-])c1>>N#CCOc1ccc(OCc2ccccc2)c([N+](=O)[O-])c1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US08309721B2,N#Cc1ccc(-n2c3ccccc3c3c(-c4nc5ccc(F)cc5[nH]4)cccc32)cc1F.NCCO.OO>>NC(=O)c1ccc(-n2c3ccccc3c3c(-c4nc5ccc(F)cc5[nH]4)cccc32)cc1NCCO,,CCO,CS(C)=O,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US05175291,CCCn1c(=O)c2[nH]c(C3CC4C=CC3C4)nc2n(CCC)c1=O>>CCCn1c(=O)c2[nH]c(C3CC4CCC3C4)nc2n(CCC)c1=O,[Pd],CCO,,[H][H],,test
US04618710,C[C@H](N)C(=O)O.O=S(=O)(Cl)c1ccccc1>>C[C@H](NS(=O)(=O)c1ccccc1)C(=O)O,,[Na+],[OH-],,,test
US20050272744A1,Cl[Mg]Cc1ccccc1.N#Cc1ccc(N2CCC(=O)CC2)cc1>>N#Cc1ccc(N2CCC(O)(Cc3ccccc3)CC2)cc1,,C1CCOC1,,,,test
US20140155596A1,CCOC(CCc1ccccc1C(=O)OC)(OCC)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1>>CCOC(CCc1ccccc1C(=O)O)(OCC)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1,,C1COCCO1,,[Na+].[OH-],,test
US20160229814A1,CCn1c(=O)[nH]c(=O)c2cc([N+](=O)[O-])ccc21.CN(C)C(=O)CCl>>CCn1c(=O)n(CC(=O)N(C)C)c(=O)c2cc([N+](=O)[O-])ccc21,,CN(C)C=O,O,[H-].[Na+],,test
US04048191,CCOC(=O)Cc1c(C(=O)OCC)ccn1C.O=C(Cl)c1ccc(Cl)cc1>>CCOC(=O)Cc1c(C(=O)OCC)cc(C(=O)c2ccc(Cl)cc2)n1C,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100137281A1,CC(C)(C)C1CO1.CCc1cc2c(=O)[nH]c(=O)n(Cc3ccc(-c4ccccc4C#N)cc3)c2s1>>CCc1cc2c(=O)n(CC(O)C(C)(C)C)c(=O)n(Cc3ccc(-c4ccccc4C#N)cc3)c2s1,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20070105904A1,C#Cc1cccnc1N.ON=C(Cl)Cc1cccc(Oc2ccccc2)c1>>Nc1ncccc1-c1cc(Cc2cccc(Oc3ccccc3)c2)no1,,O,,C1CCOC1,CCN(CC)CC,test
US04332614,CCCNc1c(C)cccc1OCCOCCOC.O=C(Cl)CCl>>CCCN(C(C)=O)c1c(C)cccc1OCCOCCOC,,ClCCl,,[Na+].[OH-],,test
US20120329784A1,Cc1cccc(N)c1.Clc1cc(Cl)ncn1>>Cc1cccc(Nc2cc(Cl)ncn2)c1,,CC(C)O,,,,test
US20080085890A1,CN1CCN(c2ccc(N)c(F)n2)CC1.CO/C=C1/C(=O)NC(=O)c2ccc(I)cc21>>CN1CCN(c2ccc(N/C=C3\C(=O)NC(=O)c4ccc(I)cc43)c(F)n2)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US20070093526A1,CC(C)CN(Cc1scnc1Cl)C1CCNCC1.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>CC(C)CN(Cc1scnc1Cl)C1CCNCC1.O=C(O)[C@H](O)[C@@H](O)C(=O)O,,CCO,,,,test
US04423070,BrBr.CC(=O)OCc1cc(C(C)=O)ccc1OC(C)=O>>CC(=O)OCc1cc(C(=O)CBr)ccc1OC(C)=O,,ClC(Cl)Cl,,,,test
US20140162967A1,Cc1cc(/C=C/CCN2CCCC3(CCN(C(=O)OC(C)(C)C)CC3)C2)ccc1Cc1c(O[C@@H]2O[C@H](COC(=O)c3ccccc3)[C@@H](OC(=O)c3ccccc3)[C@H](OC(=O)c3ccccc3)[C@H]2OC(=O)c2ccccc2)n[nH]c1C(C)C.Cl.ClCCl>>Cc1cc(/C=C/CCN2CCCC3(CCNCC3)C2)ccc1Cc1c(O[C@@H]2O[C@H](COC(=O)c3ccccc3)[C@@H](OC(=O)c3ccccc3)[C@H](OC(=O)c3ccccc3)[C@H]2OC(=O)c2ccccc2)n[nH]c1C(C)C.Cl.Cl,,ClCCl,,,,test
US20120122941A1,C[C@@H](N[C@H]1CC[C@@H](c2ccc(OCC#N)cc2)C1)c1cccc2ccccc12.[Cl-].[N-]=[N+]=[N-].[NH4+]>>C[C@@H](N[C@H]1CC[C@@H](c2ccc(OCc3nn[nH]n3)cc2)C1)c1cccc2ccccc12.Cl,,CN(C)C=O,,O,,test
US20120088755A1,Cc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1O>>Cc1cc(N)cc(N)c1O,[Ni],CO,,[H][H],,test
US20160024044A1,N#CCc1ccc(Cl)c(Cl)c1.O=Cc1ccccc1>>N#CC(c1ccc(Cl)c(Cl)c1)C(O)c1ccccc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20060024330A1,BrCc1ccccc1.CC(=O)N1CC(=O)N(Cc2ccc(F)cc2)C2C(CO)C21>>CC(=O)N1CC(=O)N(Cc2ccc(F)cc2)C2C(COCc3ccccc3)C21,,C1CCOC1,,[H-].[Na+],,test
US20110015212A1,Brc1ncnc2[nH]cnc12.CC(N)c1nc2sccn2c(=O)c1-c1ccccc1>>CC(Nc1ncnc2[nH]cnc12)c1nc2sccn2c(=O)c1-c1ccccc1,,CCO,,CCN(C(C)C)C(C)C,,test
US20140073658A1,N#Cc1ncc(C(F)(F)F)cc1Oc1ccc(F)cc1F.O=S(=O)(O)O>>NC(=O)c1ncc(C(F)(F)F)cc1Oc1ccc(F)cc1F,,O=S(=O)(O)O,,O=C([O-])O.[Na+],,test
US20050054658A1,CCCCOC(=O)[C@@H]1CC[C@H](CO)CC1.CS(=O)(=O)Cl>>CCCCOC(=O)[C@@H]1CC[C@H](COS(C)(=O)=O)CC1,,ClCCl,,CCN(CC)CC,,test
US20080039468A1,CC(C)(C)OC(=O)CC(=O)[O-].CC1Cc2nnc(-c3cccc(C(F)(F)F)c3)cc2C(O)C1.ClCCCl>>CC1Cc2nnc(-c3cccc(C(F)(F)F)c3)cc2C(OC(=O)CC(=O)O)C1.Cl,,CN(C)C=O,O,CCOC(C)=O,,test
US05059691,C1CCNC1.CC(=O)CC(=O)c1ccccc1>>C/C(=C/C(=O)c1ccccc1)N1CCCC1,,CCOC(C)=O,,,,test
US05859007,Cc1ccc(NC(C)C)cc1.O=C(Br)CBr>>Cc1ccc(N(C(=O)CBr)C(C)C)cc1,,ClCCl,,CCN(CC)CC,,test
US20040009965A1,CN.O=C(O)c1csc(-c2cc3nccc(Cl)c3s2)n1>>CNC(=O)c1csc(-c2cc3nccc(Cl)c3s2)n1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20140228409A1,CCCBr.O=[N+]([O-])c1ccc2[nH]c3c(c2c1)CCCC3>>CCCn1c2c(c3cc([N+](=O)[O-])ccc31)CCCC2,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070191370A1,Cc1ccc(C(O)C(F)(F)F)cc1.Nc1nc(Cl)cc(Cl)n1>>Cc1ccc(C(Oc2cc(Cl)nc(N)n2)C(F)(F)F)cc1,,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US05496826,CCC(=O)Cl.Nc1ccccc1-c1nc2ccccc2[nH]1>>CCC(=O)Nc1ccccc1-c1nc2ccccc2[nH]1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090221555A1,CC(C)(CNS(C)(=O)=O)Nc1nc(Cl)ncc1Cl.COCCN1CCc2ccc(N)cc2CC1>>COCCN1CCc2ccc(Nc3ncc(Cl)c(NC(C)(C)CNS(C)(=O)=O)n3)cc2CC1,,CC(C)O,,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US20150307497A1,BrBr.Oc1ccc(C(F)(F)F)cc1F>>Oc1c(F)cc(C(F)(F)F)cc1Br,,CC(=O)O,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US05910605,Cc1c(O)cccc1Cl.N#C[Cu]>>Cc1c(O)cccc1C#N,,c1ccncc1,,,,test
US20100311693A1,CN(C)C(=O)Cl.FC(F)COc1ccc(Cl)cc1-c1cccn2nc(Nc3ccc4c(c3)CCNCC4)nc12>>CN(C)C(=O)N1CCc2ccc(Nc3nc4c(-c5cc(Cl)ccc5OCC(F)F)cccn4n3)cc2CC1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20100029606A1,CC(C)[Si](Cl)(C(C)C)C(C)C.COC(=O)c1ccc2[nH]ccc2c1>>COC(=O)c1ccc2c(ccn2[Si](C(C)C)(C(C)C)C(C)C)c1,,CN(C)C=O,,[H-].[Na+],,test
US04816464,C1CC2(CCN1)OCCO2.C=CCCCBr>>C=CCCCN1CCC2(CC1)OCCO2,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20070254892A1,CC(C)[Mg]Cl.O=Cc1cccc(Br)c1>>CC(C)C(O)c1cccc(Br)c1,,C1CCOC1,,Cl,,test
US04826990,O=[N+]([O-])c1cccc(OCc2cccc(-c3ccccc3)n2)c1>>Nc1cccc(OCc2cccc(-c3ccccc3)n2)c1,,CCOC(C)=O,O,Cl,[NH4+].[OH-],test
US20090030015A1,COC(=O)Cc1ccc(-c2ccccc2NC(=O)c2cccc(-c3cc(OC)cc(OC)c3)c2)s1>>COc1cc(OC)cc(-c2cccc(C(=O)Nc3ccccc3-c3ccc(CC(=O)O)s3)c2)c1,,CC#N,,,,test
US20150148327A1,CC(=O)N1CCNCC1.Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccnc(F)c2)c1>>CC(=O)N1CCN(c2cc(-c3cc(C)cc(Nc4nccc(C(F)(F)F)n4)c3)ccn2)CC1,,CS(C)=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20080161302A1,CN(C)c1ccc([N+](=O)[O-])cc1-c1ncco1>>CN(C)c1ccc(N)cc1-c1ncco1,[Fe],CC(=O)O,,[Na+].[OH-],,test
US05047554,COc1csc(C(=O)O)c1.NC(=O)N1C(=O)Cc2cc(Cl)ccc21>>COc1csc(C(=O)C2C(=O)N(C(N)=O)c3ccc(Cl)cc32)c1,CN(C)c1ccncc1,O=S(Cl)Cl,,,,test
US20140141034A1,C#CCOCC(CNC(=O)NNC(=O)OCC)OCC#C>>C#CCOCC(Cn1c(=O)[nH][nH]c1=O)OCC#C,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20090203763A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C(O)C[C@H]1CCCN1>>CC(C)(C)OC(=O)N1CCC[C@@H]1CC(=O)O,,CC(C)=O,O,Cl,[Na+].[OH-],test
US20030060466A1,Fc1ccc(C2=CCNCC2)cc1.N#Cc1c(Cl)nc(NCCO)nc1NCCO>>N#Cc1c(NCCO)nc(NCCO)nc1N1CC=C(c2ccc(F)cc2)CC1,,C1COCCO1,,CCN(C(C)C)C(C)C,Cl,test
US20120184587A1,COc1c(C#N)cc(C(=O)O)cc1C(C)C.O=S(Cl)Cl>>COc1c(C#N)cc(C(=O)Cl)cc1C(C)C,,CN(C)C=O,,Cc1ccccc1,,test
US20050080124A1,COc1ccc(N)cc1-c1c(Br)cnn1C.O=C=Nc1ccc(F)cc1>>COc1ccc(NC(=O)Nc2ccc(F)cc2)cc1-c1c(Br)cnn1C,,ClCCl,,,,test
US20090163592A1,CCC[C@@H](NNC(=O)c1cccc(OC)c1C)C(C)(C)C.COc1cc(C(=O)Cl)cc(OC)c1C>>CCC[C@@H](N(NC(=O)c1cccc(OC)c1C)C(=O)c1cc(OC)c(C)c(OC)c1)C(C)(C)C,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US04061656,CCc1sc(C)c(CC)c1CCl.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CCc1sc(C)c(CC)c1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Cl-],,Cc1ccccc1,,,,test
US04259504,CN(C)C=NC(=O)c1ccc([N+](=O)[O-])cc1.NNc1ccccc1>>O=[N+]([O-])c1ccc(-c2ncnn2-c2ccccc2)cc1,,CC(=O)O,,,,test
US20140357612A1,CCN(C)S(=O)(=O)Nc1cccc(C(=O)OC)c1F>>CCN(C)S(=O)(=O)Nc1cccc(CO)c1F,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150065523A1,C1CCOC1.CCOC(=O)/N=N/C(=O)OCC.Cc1ccccc1.O=C1NC(=O)c2ccccc21.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CC(C)(C)OC(=O)N1C2CC2CC[C@H]1CN1C(=O)c2ccccc2C1=O,,O,,,,test
US05629428,CCCCCCCC(=O)Cl.CCCCCCCCOc1ccc(-c2ncc(O)cc2Cl)cc1>>CCCCCCCCOc1ccc(-c2ncc(OC(=O)CCCCCCC)cc2Cl)cc1,,c1ccncc1,,,,test
US20150210682A1,CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(O)cc1CC2C(C)(C)C.OCCCCCBr>>CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCCCCCO)cc1CC2C(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06756373B1,CCCCOc1ncc(C(=O)OC)cc1-c1nc2c(CC)n(CCOC)nc2c(=O)[nH]1>>CCCCOc1ncc(C(=O)O)cc1-c1nc2c(CC)n(CCOC)nc2c(=O)[nH]1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20120101136A1,CC(C)Oc1ccc(-c2nc(-c3ccc(O)cc3)no2)cc1C#N.CCOC(=O)CBr>>CCOC(=O)COc1ccc(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)cc1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20030166644A1,CN(C(=O)Oc1ccc(NC(=O)CC(C)(C)CC(=O)O)cn1)c1ccccc1.CN1CCNCC1>>CN1CCN(C(=O)CC(C)(C)CC(=O)Nc2ccc(OC(=O)N(C)c3ccccc3)nc2)CC1,CN(C)C=O,ClCCl,,O=S(Cl)Cl,,test
US06150524,Brc1ccccn1.COCOc1ccc2c3c1O[C@H]1[C@@H](O)C=C[C@H]4[C@@H](C2)N(C)CC[C@@]341>>COCOc1ccc2c3c1O[C@H]1[C@@H](Oc4ccccn4)C=C[C@H]4[C@@H](C2)N(C)CC[C@@]341,,CN(C)C=O,,[H-].[Na+],,test
US20070043040A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=S(=O)(NCCNCCOc1ccccc1Cc1ccccc1)c1cccc2cnccc12>>CC(C)(C)OC(=O)N(CCNS(=O)(=O)c1cccc2cnccc12)CCOc1ccccc1Cc1ccccc1,,ClCCl,,,,test
US20160002218A1,CC(=O)OC(C)=O.Cc1cc(OC(F)(F)F)cc(-c2csc(N)n2)c1>>CC(=O)Nc1nc(-c2cc(C)cc(OC(F)(F)F)c2)cs1,,CCOC(C)=O,,c1ccncc1,,test
US20090291945A1,CC[C@@H](CNc1ccc(OCC(=O)O)cc1OC)NC(=O)[C@H](CC(C)(C)F)N[C@@H](c1ccccc1)C(F)(F)F.N>>CC[C@@H](CNc1ccc(OCC(N)=O)cc1OC)NC(=O)[C@H](CC(C)(C)F)N[C@@H](c1ccccc1)C(F)(F)F,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150361060A1,NCC(=O)N1C2CCC1CC2>>NCCN1C2CCC1CC2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100160369A1,C=CCBr.Oc1cc(Cl)c(-c2nnc(-c3cn4cc(C(F)(F)F)cc(Cl)c4n3)s2)cc1F>>C=CCOc1cc(Cl)c(-c2nnc(-c3cn4cc(C(F)(F)F)cc(Cl)c4n3)s2)cc1F,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US06090820,CC(=O)NC[C@H]1CN(c2ccc(N3C[C@@H]4CNC[C@@H]4C3)c(F)c2)C(=O)O1.O=C(Cl)COCc1ccccc1>>CC(=O)NC[C@H]1CN(c2ccc(N3C[C@@H]4CN(C(=O)COCc5ccccc5)C[C@@H]4C3)c(F)c2)C(=O)O1,,ClCCl,,CCN(CC)CC,,test
US20120053173A1,CCOC(=O)CCNC(=O)c1ccc(NC(c2oc3ccc(O)cc3c2C)C2CCCCC2)cc1.OCc1ccc(Cl)nc1>>CCOC(=O)CCNC(=O)c1ccc(NC(c2oc3ccc(OCc4ccc(Cl)nc4)cc3c2C)C2CCCCC2)cc1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20050096375A1,CCc1ccc(CN2CC3C(CNc4ccc(N5CCOCC5)c(F)c4)C3C2)cc1.O=C(Cl)c1cc2ccccc2s1>>CCc1ccc(CN2CC3C(C2)C3CN(C(=O)c2cc3ccccc3s2)c2ccc(N3CCOCC3)c(F)c2)cc1,,ClCCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20090105259A1,COC[C@@H](CN(CCCCNC(=O)OC(C)(C)C)C(=O)NC(C)C)OC(=O)Nc1ccccc1>>COC[C@@H](CN(CCCCN)C(=O)NC(C)C)OC(=O)Nc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080153812A1,CC(C)(C)OC(=O)N1CCN(c2cccc(C(=O)O)c2)CC1.COc1cc(COc2cc(N)n(C(=O)OC(C)(C)C)n2)cc(OC)c1>>COc1cc(COc2cc(NC(=O)c3cccc(N4CCNCC4)c3)n[nH]2)cc(OC)c1,,C1CCOC1,C1COCCO1,Cl,c1ccncc1,test
US20090036456A1,CI.OCc1ccc2cc(Br)ccc2c1>>COCc1ccc2cc(Br)ccc2c1,,O,,CN(C)C=O,[H-].[Na+],test
US20160185780A1,C/C=C/C#N.CN1CCC(N(C)C(=O)c2ccc(Nc3nc4c(C5=CCNCC5)cccn4n3)cc2)CC1>>CC(CC#N)N1CC=C(c2cccn3nc(Nc4ccc(C(=O)N(C)C5CCN(C)CC5)cc4)nc23)CC1,,OCC(O)CO,,CCN(CC)CC,,test
US20110021522A1,Nc1cccc(-c2cccc3[nH]ccc23)c1.O=C(O)c1cc2cccc(O)c2oc1=O>>O=C(Nc1cccc(-c2cccc3[nH]ccc23)c1)c1cc2cccc(O)c2oc1=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090036450A1,CCN(CC)S(=O)(=O)c1ccsc1C(=O)O>>CCN(CC)S(=O)(=O)c1ccsc1CO,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US20130237533A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)CC(CN)NC(=O)OCc1ccccc1>>CC(C)CC(CNC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1,,C1CCOC1,,CCOC(C)=O,[Na+].[OH-],test
US09153785B2,CCCCC(CCCC)C(=O)OCC>>CCCCC(CO)CCCC,,C1CCOC1,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US04910306,Cc1cc(C)n2nc(S(=O)(=O)Cl)nc2n1.Cc1ccc(Cl)c(N[Si](C)(C)C)c1Cl>>Cc1cc(C)n2nc(S(=O)(=O)Nc3c(Cl)ccc(C)c3Cl)nc2n1,,CC#N,,CS(C)=O,,test
US20030232790A1,CCCc1c(O)ccc2c1CCCC2=O.OCCc1cncn1Cc1ccccc1>>CCCc1c(OCCc2cncn2Cc2ccccc2)ccc2c1CCCC2=O,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080194535A1,CI.O=Cc1cc(O)ccc1Br>>COc1ccc(Br)c(C=O)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160176864A1,Cc1nnn(C)c1-c1cnc2c(c1)[nH]c1cc(Cl)ccc12.O[C@@H](c1ccccc1)C1CCOCC1>>Cc1nnn(C)c1-c1cnc2c3ccc(Cl)cc3n([C@H](c3ccccc3)C3CCOCC3)c2c1,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100240896A1,Brc1cccc(P(c2ccccc2)c2ccccc2)n1.O=C=O>>O=C(O)c1cccc(P(c2ccccc2)c2ccccc2)n1,,ClCCl,,[Li]CCCC,,test
US20030092712A1,CC(C)(C)N1CCC(=O)CC1>>CC(C)(C)N1CCC(O)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100069310A1,CCc1ccc(Cc2cc([C@@]3(O)O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)cc(C#N)c2C)cc1>>CCc1ccc(Cc2cc([C@@]3(O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc(C#N)c2C)cc1,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20090053192A1,Cc1cccc(NC(N)=S)n1.O=C(CBr)c1ccccn1>>Cc1cccc(Nc2nc(-c3ccccn3)cs2)n1,,CCO,,,,test
US04367234,C1CCOC1.CCOC(=N)C(O)c1c(OC)cccc1[N+](=O)[O-]>>COc1cccc([N+](=O)[O-])c1C1OC(=O)NC1=O,,Cc1ccccc1,,CCN(CC)CC,Cl,test
US20020183319A1,CN1CCN(C(=O)c2ccc(C=O)[nH]2)CC1.O=C1Cc2c(ncnc2Nc2ccc(F)c(Cl)c2)N1>>CN1CCN(C(=O)c2ccc(C=C3C(=O)Nc4ncnc(Nc5ccc(F)c(Cl)c5)c43)[nH]2)CC1,C1CCNCC1,CCO,,,,test
US20030105089A1,COC(=O)C(NC(C)=O)P(=O)(OC)OC.O=Cc1ccoc1C=O>>COC(=O)c1cc2occc2cn1,,ClC(Cl)Cl,,C1CCC2=NCCCN2CC1,,test
US20130317001A1,NS(=O)(=O)N1CCC1.O=C(O)c1cc(Cl)c(COC2CCCCC2)cc1F>>O=C(NS(=O)(=O)N1CCC1)c1cc(Cl)c(COC2CCCCC2)cc1F,,C1CCOC1,CCOC(C)=O,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US20100216746A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1cc2ccc(O[Si](C)(C)C(C)(C)C)cc2[nH]1>>COC(=O)c1cc2ccc(O[Si](C)(C)C(C)(C)C)cc2n1C(=O)OC(C)(C)C,CN(C)c1ccncc1,C1CCOC1,,,,test
US03980089,COC1CCC(OC)O1.Nc1ccncc1>>c1ccn(-c2ccncc2)c1,,CC(=O)O,,,,test
US20040092598A1,COC(=O)CCCCCNC(=O)CC=Cc1ccccc1.NO>>O=C(CCCCCNC(=O)C/C=C/c1ccccc1)NO,,CO,,Cl,C[O-].[Na+],test
US20110212937A1,C=C(c1ccccc1)c1nc(Cl)nc(Cl)c1C=O.C=C[Mg]Br>>C=CC(O)c1c(Cl)nc(Cl)nc1C(=C)c1ccccc1,,C1CCOC1,,CCOC(C)=O,[Cl-].[NH4+],test
US20080045742A1,CO.COc1ccc(C=CC=O)cc1>>COC(=O)C=Cc1ccc(OC)cc1,,Cc1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US04438207,CCCCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21.CCOC(=O)CCCBr>>CCCCCc1cc(OCCCC(=O)O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090227566A1,CC(C)O.COC(=O)c1ccc(O)cc1OC1CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)c1ccc(OC(C)C)cc1OC1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140275085A1,CC(C)(C)N.COc1nc(SC)ncc1-c1ccc(Oc2ccnc(-c3cnn(C)c3)c2)c(C)n1>>COc1nc(NC(C)(C)C)ncc1-c1ccc(Oc2ccnc(-c3cnn(C)c3)c2)c(C)n1,,ClCCl,,O=C(OO)c1cccc(Cl)c1,,test
US20090247499A1,CC(C)(C)OC(=O)N1CCNCC1.O=S(=O)(Cl)c1cccc2ccccc12>>CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2cccc3ccccc23)CC1,,CC#N,,CCN(CC)CC,,test
US20160137952A1,COC(=O)[C@H]1OC(O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.N#CC(Cl)(Cl)Cl>>COC(=O)[C@H]1OC(OC(=N)C(Cl)(Cl)Cl)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US04536402,CN(C)/C(=C1/Sc2ccccc2C1=O)c1ccccc1.OO>>CN(C)/C(=C1\C(=O)c2ccccc2S1=O)c1ccccc1,,CC(=O)O,,,,test
US20040063954A1,N#CC=C1CCN(c2ccc(N3C[C@H](CN)OC3=O)cc2F)CC1.O=C(O)C(F)F>>N#CC=C1CCN(c2ccc(N3C[C@H](CNC(=O)C(F)F)OC3=O)cc2F)CC1,,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20110294812A1,CC(C)(C)[Si](C)(C)Cl.CC(C)(C)c1cc(N)n(-c2ccc(CO)cc2)n1>>CC(C)(C)c1cc(N)n(-c2ccc(CO[Si](C)(C)C(C)(C)C)cc2)n1,,CN(C)C=O,O,c1c[nH]cn1,,test
US06153640,COC(=O)[C@]12CN(Cc3ccccc3)C[C@H]1c1ccccc12>>OC[C@]12CN(Cc3ccccc3)C[C@H]1c1ccccc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040186301A1,CC(C)(C)OC(=O)CBr.COC(=O)CCCC(=O)[O-]>>COC(=O)C(CCC(=O)O)CC(=O)OC(C)(C)C,,C1CCOC1,CN(C)P(=O)(N(C)C)N(C)C,CC(C)NC(C)C,[Li]CCCC,test
US05556850,CC(I)OC(=O)C(C)(C)C.COCC1=C(C(=O)O)N2C(=O)C(N)[C@H]2SC1.O=C(Cl)/C(=N\OC(c1ccccc1)(c1ccccc1)c1ccccc1)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>COCC1=C(C(=O)OC(C)OC(=O)C(C)(C)C)N2C(=O)C(NC(=O)/C(=N\OC(c3ccccc3)(c3ccccc3)c3ccccc3)c3csc(NC(c4ccccc4)(c4ccccc4)c4ccccc4)n3)[C@H]2SC1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20060084643A1,N#C[Cu].Nc1ccc(C(F)(F)F)cc1Br>>N#Cc1cc(C(F)(F)F)ccc1N,,CCOC(C)=O,CN1CCCC1=O,,,test
US20020002163A1,CC(=O)c1sccc1CBr.CC(C)C1=NC(NC(=O)OC(C)(C)C)C(=O)Nc2ccccc21>>CC(=O)c1sccc1CN1C(=O)C(NC(=O)OC(C)(C)C)N=C(C(C)C)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20020072516A1,COC(=O)[C@H](CSC)NC(=O)CCCCNC(=O)OC(C)(C)C>>COC(=O)[C@H](CSC)NC(=O)CCCCN,,C1COCCO1,Cl,,,test
US08598345B2,CN(c1cccnc1)c1ccnc(C(=O)O)c1.Cc1csc(N)n1>>Cc1csc(NC(=O)c2cc(N(C)c3cccnc3)ccn2)n1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150148313A1,CC(C)(C)[Si](C)(C)Cl.C[C@H](O)CO>>C[C@@H](O)CO[Si](C)(C)C(C)(C)C,,CN(C)C=O,,c1c[nH]cn1,,test
US20080287475A1,CN(c1nc(Cl)nc(Cl)c1F)S(C)(=O)=O.Cc1cc(N)n[nH]1>>Cc1cc(Nc2nc(Cl)nc(N(C)S(C)(=O)=O)c2F)n[nH]1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20110118251A1,COC(=O)Cl.Fc1ccccn1>>COC(=O)c1cccnc1F,,C1CCOC1,,O,CC(C)[N-]C(C)C.[Li+],test
US04363807,O=C(Cc1ccccc1)NC1C(=O)N2C(C(=O)O)C(CO)CS[C@H]12.[N-]=[N+]=C(c1ccccc1)c1ccccc1>>O=C(Cc1ccccc1)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)C(CO)CS[C@H]12,,C1CCOC1,CCOC(C)=O,CC(=O)O,,test
US20050239751A1,C#Cc1cccc(N)c1.O=C(CCCl)c1ccc(F)cc1>>C#Cc1cccc(NCCC(=O)c2ccc(F)cc2)c1,,C1CCOC1,,CCN(CC)CC,,test
US20160039838A1,Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1.O=C(Cl)/C=C/CBr>>O=C(/C=C/CBr)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1,,C1CCOC1,,O,,test
US20090281088A1,BrCc1ccc(Br)s1.O=[N+]([O-])c1cn2c(n1)OC[C@@H](O)C2>>O=[N+]([O-])c1cn2c(n1)OC[C@@H](OCc1ccc(Br)s1)C2,,CN(C)C=O,,[H-].[Na+],,test
US20090036492A1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.Cc1cc(Br)c2ccccc2c1C=O>>COc1cc(O)c2c(c1C(=O)NCc1c(C)cc(Br)c3ccccc13)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20130324501A1,O=C(O)c1cccn1S(=O)(=O)c1ccc([N+](=O)[O-])cc1.[O-][n+]1cc(Cl)c(C[C@H](O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1>>O=C(O[C@@H](Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1)c1cccn1S(=O)(=O)c1ccc([N+](=O)[O-])cc1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20120122918A1,Cc1ccc(C(N)=S)cc1.O=C(CCl)CCl>>Cc1ccc(-c2nc(CCl)cs2)cc1,,Cc1ccccc1,,,,test
US20090054435A1,COC(=O)[C@H](C)O.COc1cc(C)c(C(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c(O)c1>>COc1cc(C)c(C(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c(O[C@H](C)C(=O)O)c1,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100256113A1,BrCCCCOCc1ccccc1.Oc1ccc(F)cc1>>Fc1ccc(OCCCCOCc2ccccc2)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060069123A1,O=C(O)C(C1CCN(C(=O)C=Cc2cc(F)c(F)c(F)c2)CC1)N1CCC(c2c[nH]c3ccccc23)CC1>>O=C(O)C(C1CCN(C(=O)/C=C/c2cc(F)c(F)c(F)c2)CC1)N1CCC(c2c[nH]c3ccccc23)CC1,,CC#N,CO,,,test
US20050165048A1,O=[N+]([O-])c1ccc(F)c(-c2cccnc2)c1>>Nc1ccc(F)c(-c2cccnc2)c1,O=[Pt]=O,CCO,CCOC(C)=O,[H][H],,test
US20020094989A1,CCNC1CCN(C(=O)OC(C)(C)C)CC1.O=S(=O)(Cl)c1ccccc1>>CCN(C1CCN(C(=O)OC(C)(C)C)CC1)S(=O)(=O)c1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20130018098A1,C=C/C(C#N)=C/[C@@H]1[C@@H](C(=O)O)C1(C)C.O=S(Cl)Cl>>C=C/C(C#N)=C/[C@@H]1[C@@H](C(=O)Cl)C1(C)C,CN(C)C=O,C1CCOC1,,,,test
US06005116,CN(C)CCOc1cc(-c2ccccc2)on1.Cl>>CN(C)CCOc1cc(-c2ccccc2)on1.Cl,,C1COCCO1,,,,test
US20160200674A1,C=CC(c1ccccc1)c1cc(Br)cc([N+](=O)[O-])c1O.C=CCBr>>C=CCOc1c(C(C=C)c2ccccc2)cc(Br)cc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150152080A1,COC(=O)c1ccccc1CSc1ccc(C)cc1NS(=O)(=O)c1cc2ccccc2s1>>Cc1ccc(SCc2ccccc2C(=O)O)c(NS(=O)(=O)c2cc3ccccc3s2)c1,,CO,,Cl,[Na+].[OH-],test
US20100197715A1,Br[Mg]c1ccccc1.O=C1CCCN(C(=O)OCc2ccccc2)C1>>O=C(OCc1ccccc1)N1CCCC(O)(c2ccccc2)C1,,C1CCOC1,,,,test
US20130264554A1,Cc1ccc(-c2cn(C)cn2)s1.II>>Cc1ccc(-c2cn(C)c(I)n2)s1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US05712284,COc1ccc(CCN2C3CCC2CC(=O)C3)cc1OC.COc1ccc(N)cc1OC>>COc1ccc(CCN2C3CCC2CC(Nc2ccc(OC)c(OC)c2)C3)cc1OC,,CO,,[BH3-]C#N.[Na+],,test
US20020183320A1,Nc1nc[nH]n1.O=Cc1cccnc1.[C-]#[N+]C(C)(C)C>>CC(C)(C)Nc1c(-c2cccnc2)nc2nc[nH]n12,,[O-][Cl+3]([O-])([O-])O,,,,test
US20160158207A1,CC(=O)N1CCC(=O)CC1.CI.Fc1cc(Br)ccc1N=C=S>>CS/C(Nc1ccc(Br)cc1F)=C1/CN(C(C)=O)CCC1=O,,C1CCOC1,,CC(C)(C)O[K],,test
US20150112058A1,COP(=O)(CC(=O)OC(C)(C)C)OC.O=Cc1cc(Cl)ccc1-n1cncn1>>CC(C)(C)OC(=O)/C=C/c1cc(Cl)ccc1-n1cncn1,,C1CCOC1,,[H-].[Na+],,test
US05730902,C1CCOC1.CCCCC[Si]1(c2ccccc2)CCC([C@@H]2CC[C@@H](c3cc(F)c(O)c(F)c3)CC2)CC1.CCOC(=O)/N=N/C(=O)OCC.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CCCCCCC(C)Oc1c(F)cc([C@@H]2CC[C@@H](C3CC[Si](CCCCC)(c4ccccc4)CC3)CC2)cc1F,,C1CCOC1,,,,test
US20100210674A1,O=C1Cc2ccc(Cl)cc2N1.O=CC1=CCCC1>>O=C1Nc2cc(Cl)ccc2/C1=C/C1=CCCC1,,CO,,C1CCNCC1,,test
US20030144320A1,CC(C)(C)c1ccc(C(=O)O)cc1Br.CCN=C=NCCCN(C)C.CN.On1nnc2ccccc21>>CN1CCc2ccc(NC(=O)c3ccc(C(C)(C)C)c(Br)c3)cc2C1,,CN(C)C=O,,,,test
US20070054909A1,COC(=O)c1cc(Cl)c(OCC2CCCN2)c(Cl)c1.COc1cc(CC(=O)Oc2c(F)c(F)c(F)c(F)c2F)ccc1NC(=O)Nc1ccccc1C>>COC(=O)c1cc(Cl)c(OCC2CCCN2C(=O)Cc2ccc(NC(=O)Nc3ccccc3C)c(OC)c2)c(Cl)c1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,,test
US05374646,Cc1nc(C)n(Cc2ccc3oc(-c4ccccc4NS(=O)(=O)C(F)(F)F)c(Br)c3c2)c1C(=O)O.O=C(n1ccnc1)n1ccnc1>>CNC(=O)c1c(C)nc(C)n1Cc1ccc2oc(-c3ccccc3NS(=O)(=O)C(F)(F)F)c(Br)c2c1,,C1CCOC1,,,,test
US04985419,CCN(CC)CC(C)N1c2ccccc2Sc2ccc(C#N)cc21.S>>NC(=S)c1ccc2c(c1)Nc1ccccc1S2,,c1ccncc1,,CCN(CC)CC,,test
US20100280011A1,CC(C)[Si](Oc1ccc(C(CNC(=O)OC(C)(C)C)C(=O)Nc2ccc3cnccc3c2)cc1)(C(C)C)C(C)C>>CC(C)(C)OC(=O)NCC(C(=O)Nc1ccc2cnccc2c1)c1ccc(O)cc1,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05708172,NN1CCN(C(=O)OCc2ccccc2)CC1.O=C(Cl)c1ccc(F)cc1>>O=C(NN1CCN(C(=O)OCc2ccccc2)CC1)c1ccc(F)cc1,,CCN(CC)CC,,,,test
US20160200681A1,CN.O=C1CCc2c1cn(S(=O)(=O)c1cccc(Cl)c1)c2-c1ccccc1F>>CNC1CCc2c1cn(S(=O)(=O)c1cccc(Cl)c1)c2-c1ccccc1F,CC(C)O[Ti](OC(C)C)(OC(C)C)OC(C)C,CO,,C1CCOC1,[BH4-].[Na+],test
US20140163024A1,Nc1cccc(Cl)c1.O=S(=O)(Cl)Cc1ccc(Br)cc1>>O=S(=O)(Cc1ccc(Br)cc1)Nc1cccc(Cl)c1,,ClCCl,,Cl,c1ccncc1,test
US20100190852A1,COC(=O)c1cc(C=O)cc(C(=O)OC)c1.C[N+](=O)[O-]>>COC(=O)c1cc(C(=O)OC)cc(C(O)C[N+](=O)[O-])c1,,CO,,CCN(CC)CC,,test
US20120035070A1,CC(C)(C)[Si](C)(C)Oc1cccc(CO)c1.CS(=O)(=O)Cl>>CC(C)(C)[Si](C)(C)Oc1cccc(CCl)c1,,ClCCl,,CCN(CC)CC,O,test
US20020040029A1,CC(=O)c1ccccc1.COc1cccc(OC)c1C=O>>COc1cccc(OC)c1C=CC(=O)c1ccccc1,,CO,O,[Na+].[OH-],,test
US20050131001A1,CSc1nc(C)ccc1NC(=O)CCCCCBr.Sc1nc2ccccc2o1>>CSc1nc(C)ccc1NC(=O)CCCCCSc1nc2ccccc2o1,,CN(C)C=O,O,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US04804762,CC(C)C(N)C#N.O=C(Cl)c1ccnc(Cl)c1>>CC(C)C(C#N)NC(=O)c1ccnc(Cl)c1,,CCOC(C)=O,ClCCl,CCN(CC)CC,O,test
US20150141401A1,CCC(=O)NN.O=C(O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1>>CCC(=O)NNC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1,,C1CCOC1,,CC(C)COC(=O)Cl,CCN(CC)CC,test
US20090312381A1,COCCNC(=O)NNC(=O)c1ccc(Cl)cc1>>COCCn1c(-c2ccc(Cl)cc2)n[nH]c1=O,,[Na+],[OH-],Cl,,test
US05286650,COC(=O)/C(Cl)=C(/C)OC.N.O=Cc1ccccc1>>O=C1CC(=O)/C(=C/c2ccccc2)N1,,O,,Cl,[Na+].[OH-],test
US20090149456A1,Cc1ncoc1-c1cccc([N+](=O)[O-])c1>>Cc1ncoc1-c1cccc(N)c1,[Pd],CO,,,,test
US20120035208A1,CC1(C)OB(c2ccc3[nH]ncc3c2)OC1(C)C.Cn1ncc2c(Cl)cc(Cl)nc21>>Cn1ncc2c(Cl)cc(-c3ccc4[nH]ncc4c3)nc21,,C1COCCO1,,CC(=O)[O-].[K+],,test
US06329381B1,Nc1nc(S)nc2c1nc(O)n2Cc1ccccc1.OCCBr>>Nc1nc(SCCO)nc2c1nc(O)n2Cc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05223528,CO.O=C(O)C(C(=O)O)c1ccccc1>>COC(=O)C(C(=O)O)c1ccccc1,CN(C)C=O,CCOCC,,O=S(Cl)Cl,,test
US20040176331A1,BrCCCCCCBr.CC(C)(C)OC(=O)NCC(=O)OC/C(=C(\C(=O)O)c1ccccc1)c1ccc(S(C)(=O)=O)cc1>>CC(C)(C)OC(=O)NCC(=O)OC/C(=C(\C(=O)OCCCCCCBr)c1ccccc1)c1ccc(S(C)(=O)=O)cc1,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20040259923A1,CI.O=C(O)C(=O)Cc1ccccc1>>COC(=O)C(=O)Cc1ccccc1,,CN(C)C=O,,C1CCC2=NCCCN2CC1,Cl,test
US20110105578A1,CCN.CCOCc1nc(-c2ccc(OC[C@@H]3CO3)cc2)cn1-c1ccc(Oc2ccc(Cl)cc2)cc1>>CCNC[C@H](O)COc1ccc(-c2cn(-c3ccc(Oc4ccc(Cl)cc4)cc3)c(COCC)n2)cc1,,CO,,,,test
US20070123527A1,OCCC(c1cccnc1)c1ccc2cn[nH]c2c1>>OCC=C(c1cccnc1)c1ccc2cn[nH]c2c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120184553A1,COC(=O)Cc1cccc(N)c1.O=C(O)c1cc(Cl)ccc1OCc1ccccc1>>COC(=O)Cc1cccc(NC(=O)c2cc(Cl)ccc2OCc2ccccc2)c1,,ClCCl,,CCN(C(C)C)C(C)C,CCN=C=NCCCN(C)C,test
US20130345215A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.COCCOc1cc(F)c(Br)c(F)c1>>COCCOc1cc(F)c(C2(O)CCN(C(=O)OC(C)(C)C)CC2)c(F)c1,,CCCCCC,CCOCC,[Li]CCCC,,test
US20020091148A1,CCOC(=O)C(=O)CSC.NNc1ccccc1>>CCOC(=O)c1[nH]c2ccccc2c1SC,O=S(=O)(O)O,O,,CCO,Cl,test
US20120165347A1,CC(C)CBr.O=C1CCc2ccc(O)cc21>>CC(C)COc1ccc2c(c1)C(=O)CC2,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090099233A1,CC(C)(C)C(=O)Cl.COC(=O)C(N)C(C)=O>>COC(=O)C(NC(=O)C(C)(C)C)C(C)=O,,ClCCl,,CCN(CC)CC,Cl,test
US20060167015A1,CC(C)(C)OC(=O)Nc1cc(N2CCOCC2)cc(C(F)(F)F)c1>>Nc1cc(N2CCOCC2)cc(C(F)(F)F)c1,,CC(C)O,,Cl,,test
US20110059961A1,CC(C)(C)OC(=O)N[C@H]1CCCN(c2ccncc2NC(=O)c2csc(-c3ccccc3F)n2)C1>>N[C@H]1CCCN(c2ccncc2NC(=O)c2csc(-c3ccccc3F)n2)C1,,C1COCCO1,,Cl,,test
US04094982,CC(=O)OC(C)=O.NS(=O)(=O)c1cncc([N+](=O)[O-])c1>>CC(=O)NS(=O)(=O)c1cncc([N+](=O)[O-])c1,O=S(=O)(O)O,,,,,test
US20070167443A1,CCOC=C(C(=O)OCC)C(=O)OCC.Nc1ccccc1>>CCOC(=O)c1c[nH]c2ccccc2c1=O,,c1ccc(Oc2ccccc2)cc1,,,,test
US20110281842A1,COCOC1(c2ncc(-c3c(Cl)cnc4c3cc(-c3cnn(CCN5CCOCC5)c3)n4S(=O)(=O)c3ccc(C)cc3)s2)CCC1>>Cc1ccc(S(=O)(=O)n2c(-c3cnn(CCN4CCOCC4)c3)cc3c(-c4cnc(C5(O)CCC5)s4)c(Cl)cnc32)cc1,,CO,Cl,,,test
US20100280028A1,COc1ncc(-c2ccccc2N2CCNCC2)cn1.O=C(O)Cn1ccc2cccnc21>>COc1ncc(-c2ccccc2N2CCN(C(=O)Cn3ccc4cccnc43)CC2)cn1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(N2CCc3ccccc32)nc1-c1ccc(C)cc1>>CCCC(C(=O)O)c1c(C)nc(N2CCc3ccccc32)nc1-c1ccc(C)cc1,,CO,,[Na+].[OH-],,test
US05728686,CCOP(=O)(CCCCCl)OCC.Cn1c(=O)[nH]c(=O)c2c1ncn2Cc1ccccc1>>CCOP(=O)(CCCCn1c(=O)c2c(ncn2Cc2ccccc2)n(C)c1=O)OCC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150266890A1,N[C@H]1CCOC1.O=C(O)c1c(F)ccc(S(=O)(=O)Cl)c1F>>O=C(O)c1c(F)ccc(S(=O)(=O)N[C@H]2CCOC2)c1F,,C1CCOC1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20050014758A1,Clc1ccnc2ccccc12.c1cnc2[nH]ccc2c1>>c1cnc2c(c1)ccn2-c1ccnc2ccccc12,,CN(C)C=O,,[H-].[Na+],,test
US04694066,C=CCCCOc1ccc(-c2ccc([N+](=O)[O-])cc2)cc1.O=C(OO)c1cccc(Cl)c1>>O=[N+]([O-])c1ccc(-c2ccc(OCCCC3CO3)cc2)cc1,,ClCCl,,,,test
US20110218219A1,CCS(=O)(=O)Cl.NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1Oc1cccc(N)c1>>CCS(=O)(=O)Nc1cccc(Oc2cc(F)cc(Nc3ccc(I)cc3F)c2C(N)=O)c1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20130005707A1,Cc1cccc2nc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nn12.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nc2cccc(CBr)n2n1,,CC#N,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20110281835A1,COC1(c2cccc(F)c2F)CN(C(=O)OC(C)(C)C)C1>>COC1(c2cccc(F)c2F)CNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040038993A1,CC(C)(C)OCC(NC(=O)c1cc2nc(-c3ccc(Cl)cc3)cc(-c3ccc(Oc4ccccc4)cc3)n2n1)C(=O)OC(C)(C)C>>O=C(NC(CO)C(=O)O)c1cc2nc(-c3ccc(Cl)cc3)cc(-c3ccc(Oc4ccccc4)cc3)n2n1,,O,,O=C(O)C(F)(F)F,,test
US20130172351A1,CC(C)=CC(=O)Cl.COc1ccccc1OC>>COc1ccc(C(=O)C=C(C)C)cc1OC,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120238574A1,CCN(C(=O)OC(C)(C)C)C1CCN(Cc2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)CC1>>CCNC1CCN(Cc2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110166160A1,CI.C[C@H](N[C@H](CO)C1CC1)c1ccccc1>>COC[C@@H](N[C@@H](C)c1ccccc1)C1CC1,,C1CCOC1,,[H-].[Na+],,test
US20070049596A1,N#Cc1ccc(OCC2=C(c3cccnc3)C[C@@H](c3ccc(Cl)cc3Cl)[C@H]([N+](=O)[O-])C2)cc1>>N#Cc1ccc(OCC2=C(c3cccnc3)C[C@@H](c3ccc(Cl)cc3Cl)[C@H](N)C2)cc1,[Zn],CC(=O)O,CO,,,test
US20130079339A1,N#Cc1ccc(C(F)(F)F)cc1Cl.c1c[nH]cn1>>N#Cc1ccc(C(F)(F)F)cc1-n1ccnc1,,CN(C)C=O,,O,[H-].[Na+],test
US04071681,CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O.CC1=CS[C@@H]2[C@H](N)C(=O)N2C1C(=O)OCC(Cl)(Cl)Cl>>CC1=CS[C@@H]2[C@H](N=Cc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)C(=O)N2C1C(=O)OCC(Cl)(Cl)Cl,,O,,c1ccccc1,,test
US20140313567A1,CCCCC(CC)COc1ccc(OCC(CC)CCCC)cc1.O=[N+]([O-])O>>CCCCC(CC)COc1ccc(OCC(CC)CCCC)c([N+](=O)[O-])c1,,ClC(Cl)Cl,,O,,test
US20080085890A1,Br.COC=C1C(=O)NC(=O)c2ccc(Br)cc21.NCc1ccc(O)c(O)c1>>Br.O=C1NC(=O)c2ccc(Br)cc2C1=CNCc1ccc(O)c(O)c1,,CN(C)C=O,,CCN(CC)CC,,test
US06316482B1,COc1cc(C(=O)N(C)c2ccc(C)cc2OCCCCCC(=O)N2CCN(C)CC2)ccc1N.ClCCl.O=C(Cl)c1cccc2[nH]c(-c3ccncc3)nc12>>COc1cc(C(=O)N(C)c2ccc(C)cc2OCCCCCC(=O)N2CCN(C)CC2)ccc1NC(=O)c1cccc2[nH]c(-c3ccncc3)nc12.[Cl-].[Cl-].[Cl-],,ClCCl,,CCN(CC)CC,,test
US20090318467A1,Cc1cc(-c2cccc(C(F)(F)F)c2)nc(O)c1C(=O)N1CCC(N2CCCC2)CC1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1cc(-c2cccc(C(F)(F)F)c2)nc(OS(=O)(=O)C(F)(F)F)c1C(=O)N1CCC(N2CCCC2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100216827A1,CCOC(=O)c1ccnn1-c1ccc(Cl)cc1>>OCc1ccnn1-c1ccc(Cl)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120264749A1,COC(=O)C1CNCC2(CCN(C(=O)OC(C)(C)C)CC2)O1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>COC(=O)C1CN(CC(F)(F)F)CC2(CCN(C(=O)OC(C)(C)C)CC2)O1,,CCO,,O=C([O-])O.[Na+],,test
US20030013875A1,CC1(c2cccc(NS(C)(=O)=O)c2)C2CN(CCCc3ccccc3)CC21.Cc1ccc(S(=O)(=O)O)cc1>>CC1(c2cccc(NS(C)(=O)=O)c2)C2CN(CCCc3ccccc3)CC21.Cc1ccc(S(=O)(=O)O)cc1,,CCOC(C)=O,,,,test
US20100267689A1,CC(C)(C)OC(=O)N1CC(N)C1.O=C(O)CNC(=O)c1cccc(C(F)(F)F)c1>>CC(C)(C)OC(=O)N1CC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C1,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US05438052,CC(C)(ON)C(=O)NNC(=O)c1ccc(O)c(O)c1.Cc1nc2nc(CCC(=O)NO)cc(SCC3=C(C(=O)O)N4C(=O)[C@@H](NC(=O)C(=O)c5csc(N)n5)[C@H]4SC3)n2n1>>Cc1nc2nc(CCC(=O)NO)cc(SCC3=C(C(=O)O)N4C(=O)[C@@H](NC(=O)/C(=N\OC(C)(C)C(=O)NNC(=O)c5ccc(O)c(O)c5)c5csc(N)n5)[C@H]4SC3)n2n1,,CC(=O)N(C)C,,Cl,,test
US20030229067A1,BrCC#Cc1ccccc1.C1CNCCN1>>C(#Cc1ccccc1)CN1CCNCC1,,C1CCOC1,,,,test
US20050148624A1,CCOC(=O)C1CCN(S(=O)(=O)c2ccc(C#N)cc2)CC1>>CCOC(=O)C1CCN(S(=O)(=O)c2ccc(CN)cc2)CC1,[Ni],C1CCOC1,CCO,N,,test
US05723497,C1=COCCC1.CCCCCCCCCCCCCCCCC(O)CO>>CCCCCCCCCCCCCCCCC(O)COC1CCCCO1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20110124652A1,CCCC[Sn](CCCC)(CCCC)c1ccnnc1.C[C@H](Oc1cnc(Br)cn1)C1CCN(C(=O)OC(C)(C)C)CC1>>C[C@H](Oc1cnc(-c2ccnnc2)cn1)C1CCN(C(=O)OC(C)(C)C)CC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,CCOC(C)=O,,,test
US20050288314A1,N#Cc1c(F)cccc1F.OCc1ccc(I)cc1>>N#Cc1c(F)cccc1OCc1ccc(I)cc1,,CN(C)C=O,,O,[H-].[Na+],test
US20100076078A1,COC(=O)c1c(C)cc(C(F)(C(F)(F)F)C(F)(F)F)cc1C>>Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1C(=O)O,,C1COCCO1,CO,[Na+].[OH-],,test
US20160200706A1,C[C@H](O)CNc1nccc(-n2ccnc2C(=O)c2cccc(N)c2)n1.O=C(O)c1cccc(C(F)(F)F)c1>>C[C@H](O)CNc1nccc(-n2ccnc2C(=O)c2cccc(NC(=O)c3cccc(C(F)(F)F)c3)c2)n1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20090325967A1,CC(=O)OCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O>>O=C(CO)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(Cl)nc32)[C@H](O)[C@@H]1O,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04652556,CC(C)(N)C#N.CCCCS(=O)(=O)Cl>>CCCCS(=O)(=O)NC(C)(C)C#N,CN(C)c1ccncc1,ClC(Cl)Cl,,,,test
US20040225111A1,COc1ccc2[nH]c(N[C@@H](Cc3ccc(OCCCC(=O)NC4=NCCCN4)cc3)C(=O)OC(C)(C)C)nc2c1>>COc1ccc2[nH]c(N[C@@H](Cc3ccc(OCCCC(=O)NC4=NCCCN4)cc3)C(=O)O)nc2c1,,ClCCl,,Cc1ccccc1,O=C(O)C(F)(F)F,test
US04728650,COc1c(C)c(C)c2c(c1C)CCC(C)(C(=O)O)O2.O=S(Cl)Cl>>COc1c(C)c(C)c2c(c1C)CCC(C)(C(=O)Cl)O2,CN(C)C=O,ClCCCl,,,,test
US20020198197A1,CC(C)(C)OC(=O)Nc1cc(N2CCOCC2)c(C#N)cc1NC(=O)CC(=O)c1cccc(-n2nncc2COC2CCCCO2)c1>>N#Cc1cc2c(cc1N1CCOCC1)N=C(c1cccc(-n3nncc3CO)c1)CC(=O)N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060111553A1,COc1ncccc1CCl.Cl.N>>COc1ncccc1CN.Cl.Cl,,CO,O,,,test
US05210193,Cc1c(C(=O)C=O)sc2ccccc12.NCCN>>Cc1c(C2CNCCN2)sc2ccccc12,,C1COCCO1,CCO,O,[BH4-].[Na+],test
US20020177578A1,O=C1CCN(C(=O)CCc2ccccc2)CC1.[NH4+]>>NC1CCN(C(=O)CCc2ccccc2)CC1,,CO,,[BH3-]C#N.[Na+],,test
US20100144730A1,CC(C)(C)[SiH2]OC(C)(C)c1cnc2c(c1)c(-c1cccc(CNC(=O)c3cccn(Cc4ccc(F)c(F)c4)c3=O)c1)cn2S(=O)(=O)c1ccccc1>>O=C(NCc1cccc(-c2cn(S(=O)(=O)c3ccccc3)c3ncc(CO)cc23)c1)c1cccn(Cc2ccc(F)c(F)c2)c1=O,,CCO,,Cl,O,test
US20080146636A1,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](O)C1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N[C@H]1CC[C@H](N=[N+]=[N-])C1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060211603A1,Cc1ccc(N)c(O)c1.O=C(n1ccnc1)n1ccnc1>>Cc1ccc2[nH]c(=O)oc2c1,,CC#N,,,,test
US20140357664A1,C[C@@H]1N[C@@H](CO[Si](C)(C)C(C)(C)C)Cc2c(Br)cccc21.O=C(O)Cc1c(F)cccc1Cl>>C[C@H]1c2cccc(Br)c2C[C@H](CO[Si](C)(C)C(C)(C)C)N1C(=O)Cc1c(F)cccc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100016282A1,CCOC(=O)CCN(C(=O)OC(C)(C)C)[C@H](C)CO.[N-]=[N+]=[N-]>>CCOC(=O)CCN(C(=O)OC(C)(C)C)[C@H](C)CN=[N+]=[N-],,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05102877,CC(=O)C1=CCN(Cc2ccccc2)CC1.O=C(Cl)OCc1ccccc1>>CC(=O)C1=CCN(C(=O)OCc2ccccc2)CC1,,Cc1ccccc1,,,,test
US20080312227A1,CCOc1nc(NC(=O)C(C)(C)C)nc2ncc(-c3ccc(F)cc3)cc12>>CCOc1nc(N)nc2ncc(-c3ccc(F)cc3)cc12,,CCO,O,O=C([O-])[O-].[K+].[K+],,test
US20100056511A1,C=CC(=O)O.CNc1ccc([N+](=O)[O-])cc1>>CN(CCC(=O)O)c1ccc([N+](=O)[O-])cc1,,O,,O=S(=O)(O)O,,test
US05506190,CCCN.O=C1C2=C(CCCC2)C(=O)N1c1cc(OC2CCCC2)c(Cl)cc1F>>CCCNC(=O)C1=C(C(=O)Nc2cc(OC3CCCC3)c(Cl)cc2F)CCCC1,,c1ccccc1,,,,test
US20160022709A1,CC(C)(C)OC(=O)NCCOCCI.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CC(C)(C)OC(=O)NCCOCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[I-],,CCOC(C)=O,,,,test
US20100105667A1,COc1cc(OC)c(Cl)c(-c2ccc(C(=O)O)c3ncccc23)c1Cl.O=[N+]([O-])c1c[nH]cn1>>COc1cc(OC)c(Cl)c(-c2ccc(C(=O)Nc3cnc[nH]3)c3ncccc23)c1Cl,,CO,ClCCl,,,test
US20110053907A1,CC(C)(C)OC(=O)N1CCN(c2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4c(O)cccc43)n2)CC1>>Oc1cccc2c1nc(C(F)F)n2-c1nc(N2CCNCC2)nc(N2CCOCC2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150329525A1,Fc1ccc2[nH]ccc2c1.O=C1C=CC(=O)N1>>O=C1CC(c2c[nH]c3ccc(F)cc23)C(=O)N1,,CC(=O)O,,,,test
US20130172341A1,CC(C)(C)NN.COC(=O)C1CCC(=O)C(C(=O)c2ccncc2)C1>>COC(=O)C1CCc2c(c(-c3ccncc3)nn2C(C)(C)C)C1,,CCO,,,,test
US20120101124A1,CC(C)Oc1ccc(-c2nc(-c3ccc(OCOCC[Si](C)(C)C)c4ccoc34)no2)cc1Cl>>CC(C)Oc1ccc(-c2nc(-c3ccc(O)c4ccoc34)no2)cc1Cl,,CN(C)P(=O)(N(C)C)N(C)C,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140162971A1,CCOC(=O)c1ccc(F)c(-c2cn(C)c(=O)c3c2ccn3S(=O)(=O)c2ccc(C)cc2)c1.NC1CCCC1>>CCOC(=O)c1ccc(NC2CCCC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1,,CS(C)=O,,CCN(CC)CC,,test
US05227381,O=C(CCCCCl)N(CCN1CCCC1)CC1CCCCC1.O=c1ccc2cc(O)ccc2[nH]1>>O=C(CCCCOc1ccc2[nH]c(=O)ccc2c1)N(CCN1CCCC1)CC1CCCCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030232818A1,CC(C)(C)OC(=O)NC1CCNCC1.CCOC(=O)c1cn(CCC#N)c2nc(Cl)c(F)cc2c1=O>>CCOC(=O)c1cn(CCC#N)c2nc(N3CCC(NC(=O)OC(C)(C)C)CC3)c(F)cc2c1=O,,ClCCl,,,,test
US20100022518A1,C=CC(=O)OC.C[C@@H](N)CNC(=O)OC(C)(C)C.O=C(OCc1ccccc1)ON1C(=O)CCC1=O>>COC(=O)CCN(C(=O)OCc1ccccc1)[C@H](C)CNC(=O)OC(C)(C)C,,CO,,,,test
US20140371201A1,COc1ccc(Br)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21.OB(O)c1cccc(C(F)(F)F)c1>>COc1ccc(-c2cccc(C(F)(F)F)c2)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20060264440A1,CO.Clc1ncnc2ccc(I)cc12>>COc1ncnc2ccc(I)cc12,,CO,,C[O-].[Na+],,test
US20070043064A1,CCCCN(c1cccc(C(=O)C=CN(C)C)c1)S(=O)(=O)c1ccccc1.Nc1[nH]ncc1[N+](=O)[O-]>>CCCCN(c1cccc(-c2ccnc3c([N+](=O)[O-])cnn23)c1)S(=O)(=O)c1ccccc1,,CC(=O)O,,CCOC(C)=O,,test
US20090202943A1,CC(C)(C)C(=O)Cl.OCC(F)(F)Br>>CC(C)(C)C(=O)OCC(F)(F)Br,,C1CCOC1,,CCN(CC)CC,,test
US20160152616A1,CC1(C)OC[C@H](/C=C\CBr)O1.Cc1cc2[nH]c(=O)c(=O)n3c2c(c1C)C(C)(C)CC3>>Cc1cc2c3c(c1C)C(C)(C)CCn3c(=O)c(=O)n2C/C=C\[C@H]1COC(C)(C)O1,,CN(C)C=O,,O,[H-].[Na+],test
US20110105454A1,CCOc1ncccc1C1(O)C(=O)Nc2ccc(I)cc21.COc1ccc(S(=O)(=O)Cl)c(OC)c1>>CCOc1ncccc1C1(O)C(=O)N(S(=O)(=O)c2ccc(OC)cc2OC)c2ccc(I)cc21,,CCOCC,CN(C)C=O,O,[H-].[Na+],test
US20130331375A1,C[Si](C)(C)CCOCn1ccc2c(=O)[nH]c(Cl)nc21.Fc1ccccc1N1CCNCC1>>C[Si](C)(C)CCOCn1ccc2c(=O)[nH]c(N3CCN(c4ccccc4F)CC3)nc21,,CO,ClCCl,CCO,,test
US04902698,COC(=O)CCCc1ccc(NS(=O)(=O)c2ccccc2)cn1>>O=C(O)CCCc1ccc(NS(=O)(=O)c2ccccc2)cn1,,CCO,,Cl,[Na+].[OH-],test
US20130210844A1,CCOC(=O)c1nc(I)ccc1Cl.N#C[Cu]>>CCOC(=O)c1nc(C#N)ccc1Cl,,c1ccncc1,,O,,test
US05144057,CCC(=O)Cl.COC(=O)CC(C)=O>>CCC(=O)CC(=O)OC,,C1CCOC1,,CCN(CC)CC,Cl,test
US20040235822A1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(C(O)c4cccc[n+]4[O-])c(C)c2)CCN3C(=O)C(F)(F)F)cc1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(C(O)c4cccc[n+]4[O-])c(C)c2)CCN3)cc1,,CCO,,[BH4-].[Na+],,test
US04036962,CC(C)(C)C(=O)OCCl.O=C(O)c1cn(CC(F)(F)F)c2cc3c(cc2c1=O)OCO3>>CC(C)(C)C(=O)OCOC(=O)c1cn(CC(F)(F)F)c2cc3c(cc2c1=O)OCO3,,CCN(CC)CC,,CN(C)C=O,,test
US20090247746A1,COC(=O)c1cc2ccnc(N)c2[nH]1.O=S(=O)(Cl)c1cccs1>>COC(=O)c1cc2ccnc(NS(=O)(=O)c3cccs3)c2[nH]1,,CCOC(C)=O,,CC(=O)N(C)C,,test
US20120177681A1,BrBr.CCOP(=O)(Cc1ccc(Cn2cnc3c(N)nc(OCCOC)nc32)cc1)OCC>>CCOP(=O)(Cc1ccc(Cn2c(Br)nc3c(N)nc(OCCOC)nc32)cc1)OCC,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20070093521A1,BrCCCBr.CC(C)(C)OC(=O)N1CCC(Nc2nc3cc(O)ccc3o2)CC1>>CC(C)(C)OC(=O)N1CCC(Nc2nc3cc(OCCCBr)ccc3o2)CC1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20010046991A1,C1CCNCC1.O=[N+]([O-])c1ccc(Br)cc1>>O=[N+]([O-])c1ccc(N2CCCCC2)cc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050245544A1,COC(=O)c1n[nH]c(C(=O)OC)c1[N+](=O)[O-].COCCOCCBr>>COCCOCCn1nc(C(=O)OC)c([N+](=O)[O-])c1C(=O)OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140323463A1,CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(C)CC3)cc2)nc1Cl.Nc1cccc(N)c1>>CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(C)CC3)cc2)nc1Nc1cccc(N)c1,,CN1CCCC1=O,,,,test
US20070225324A1,C[C@@H](C(N)=O)n1ccc2c([N+](=O)[O-])cccc2c1=O>>C[C@@H](C(N)=O)n1ccc2c(N)cccc2c1=O,[Pd],ClCCl,,CO,,test
US20020111358A1,CC(=O)NCC(=O)O.COc1ccc(C=O)cc1>>COc1ccccc1C=C1N=C(C)OC1=O,,CC(=O)OC(C)=O,,CC(=O)[O-].[Na+],,test
US05958918,CCBr.O=S(=O)(O)c1ccc2ccc(O)cc2c1.[Na]>>CCOc1ccc2ccc(S(=O)(=O)O)cc2c1.[Na],,CN(C)C=O,,[H-].[Na+],,test
US04610954,CCOC(=O)c1ccc(N=C=S)cc1.CCOC(CN)OCC>>CCOC(=O)c1ccc(NC(=S)NCC(OCC)OCC)cc1,,ClC(Cl)(Cl)Cl,,,,test
US20150158851A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCC1(CO)CCC2(CC1)OCCO2>>Cc1ccc(S(=O)(=O)OCC2(CO)CCC3(CC2)OCCO3)cc1,,C1CCOC1,,[H-].[Na+],,test
US03983243,CC(=O)OCC=C(C)CCC=C(C)CCC(C)=C(C)C>>CC(=CCO)CCC=C(C)CCC(C)=C(C)C,,CO,,[Na],,test
US20040132727A1,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.NCCN1CCCCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)NCCN4CCCCC4)cc3)c2cc1OC,,ClC(Cl)Cl,O,CCN(CC)CC,,test
US20110178058A1,C1CCOC1.CC(C)(C)OC(=O)N1CCC(O)CC1.O=C(Cl)Cl>>CC(C)(C)OC(=O)N1CCC(O)CC1.O=C(O)Cl,,C1CCOC1,,Cc1ccccc1,,test
US20130274244A1,Cc1cccc(Cn2nc(C)c3c(NC(=O)c4cnc5cc(CC=O)ccn45)cccc32)n1>>Cc1cccc(Cn2nc(C)c3c(NC(=O)c4cnc5cc(CCO)ccn45)cccc32)n1,,CCO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20050182040A1,CC(C)I.NC(=O)c1ccc(NC2CCN(Cc3ccccc3)CC2)cc1O>>CC(C)Oc1cc(NC2CCN(Cc3ccccc3)CC2)ccc1C(N)=O,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US04579685,CCOC(=O)Cl.CN1CCC(N2C(=O)CN=C(c3ccccc3)c3ccccc32)CC1>>CCOC(=O)N1CCC(N2C(=O)CN=C(c3ccccc3)c3ccccc32)CC1,,c1ccccc1,,O=C([O-])O.[Na+],,test
US06281356B1,Cn1ccc2ccc(N3C(=O)CCC3=O)cc21>>c1cc2ccc(N3CCCC3)cc2[nH]1,,C1CCOC1,,[H-].[Na+],,test
US20030225057A1,CC1CN(C(=O)C(F)(F)F)CCc2cc(-c3ccnn3C)ccc21>>CC1CNCCc2cc(-c3ccnn3C)ccc21,,CO,,[Na+].[OH-],,test
US20130005716A1,COC(=O)C1NCCS1.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>COC(=O)C1SCCN1C(=O)c1ccc([N+](=O)[O-])cc1,CN(C)c1ccncc1,ClCCl,,Cl,,test
US20050228003A1,CCC(NCCN(C)C)c1nc2sccc2c(=O)n1Cc1ccccc1.O=C(Cl)c1ccc(Br)cc1>>CCC(c1nc2sccc2c(=O)n1Cc1ccccc1)N(CCN(C)C)C(=O)c1ccc(Br)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20160083361A1,C=CCOC(=O)N1CCc2c(c(=O)oc3c(C=O)c(O)ccc23)C1>>C=CCOC(=O)N1CCc2c(c(=O)oc3c(CO)c(O)ccc23)C1,,CO,,[BH4-].[Na+],,test
US20110190255A1,FC(F)(F)c1c(-c2ccccc2)noc1-c1nc(-c2ccc(C3CO3)cc2)no1.OCC1CCCNC1>>OCC1CCCN(CC(O)c2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)C1,,CC(C)O,,CS(C)=O,,test
US20040110811A1,O=C(Cl)c1cccc2ccccc12.O=C1NC(=O)C(c2ccccc2)(c2ccccc2)N1>>O=C1NC(c2ccccc2)(c2ccccc2)C(=O)N1C(=O)c1cccc2ccccc12,,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US20060229336A1,CC(C)N=C=O.Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCNCC1>>Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=O)NC(C)C)CC1,,C1CCOC1,,,,test
US20060149062A1,CC(C)(C)OC(=O)N1CCN(c2ncc(C(F)(F)F)cc2F)CC1>>Fc1cc(C(F)(F)F)cnc1N1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04543362,O=C(O)C(O)CCl.Oc1ccc(Cl)cc1>>O=C(O)C(O)COc1ccc(Cl)cc1,,[Na+],[OH-],Cl,,test
US20150137083A1,O=P(c1ccccc1)(c1ccccc1)c1ccc(Br)cc1.OB(O)c1ccc(/C=C/c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1>>O=P(c1ccccc1)(c1ccccc1)c1ccc(-c2ccc(/C=C/c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,O,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20140315895A1,C=CC[C@]1(COCC[Si](C)(C)C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C1=O>>C=CC[C@@]1(COCC[Si](C)(C)C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H](CC)CO)C1=O,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080207654A1,CC(C)(C)C(=O)CBr.CCOC(=O)C=C(C)[O-]>>CCOC(=O)C(CC(=O)C(C)(C)C)C(C)=O,,CN(C)C=O,,CCOC(C)=O,O,test
US06180568B2,Cc1cc(C)c(C2C(=O)N(C)N(C)C2=O)c(C)c1.O=[N+]([O-])O>>Cc1cc(C)c(C2([N+](=O)[O-])C(=O)N(C)N(C)C2=O)c(C)c1,,ClC(Cl)Cl,,,,test
US20140275030A1,CN[C@@H]1CCN(c2nc3ccc(-c4c(C)noc4C)c4c3n2[C@@H](c2ccccn2)CO4)C1.N#CCC(=O)ON1C(=O)CCC1=O>>Cc1noc(C)c1-c1ccc2nc(N3CC[C@@H](N(C)C(=O)CC#N)C3)n3c2c1OC[C@@H]3c1ccccn1,,CO,ClCCl,CCN(CC)CC,CCO,test
US20020107242A1,C[C@@H](NC(=O)c1cccc2c1NC1CCCC21)C(=O)O>>C[C@H]1NC(=O)c2cccc3c2N(C1=O)C1CCCC31,,CC(=O)O,,,,test
US20110190278A1,Cc1cc2c(cc1C(=O)N(C(C)C)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1)N(CCNC(=O)C(F)F)C(=O)C(C)(C)S2.Cl>>Cc1cc2c(cc1C(=O)N(C(C)C)[C@@H]1CCCNC1)N(CCNC(=O)C(F)F)C(=O)C(C)(C)S2.Cl,,ClC(Cl)Cl,,C1COCCO1,,test
US20060189681A1,COc1ccc(CCC2(C3CCCC3)CC(=O)C(Cl)C(=O)O2)cc1Cl.Cc1cnc2nc(S)nn2c1>>COc1ccc(CCC2(C3CCCC3)CC(O)=C(Sc3nc4ncc(C)cn4n3)C(=O)O2)cc1Cl,,O,,,,test
US20080188528A1,CC(c1ccccc1)n1cccc(C(=O)O)c1=O.Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)c2cccn(C(C)c3ccccc3)c2=O)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04521598,[N-]=[N+]=NC1=C(C(=O)OCc2ccc([N+](=O)[O-])cc2)N2C(=O)[C@@H](NC(=O)Cc3cccs3)[C@H]2SC1>>[N-]=[N+]=NC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)Cc3cccs3)[C@H]2SC1,[Zn],O,,C1CCOC1,Cl,test
US20130115190A1,CC(C)Oc1ccc(C#N)cc1F.CCN(CC)C(=O)c1ccc(OC)cc1C>>COc1ccc2c(O)nc(-c3ccc(OC(C)C)c(F)c3)cc2c1,,C1CCOC1,,CCCCC,[Li]C(C)(C)C,test
US20080139631A1,N.N#Cc1ccc2c(cc(C(=O)O)n2CC(F)(F)F)c1Cl>>N#Cc1ccc2c(cc(C(N)=O)n2CC(F)(F)F)c1Cl,,CO,Cc1ccccc1,CN(C)C=O,O=S(Cl)Cl,test
US20100093757A1,CCOC[C@H](O[Si](C)(C)C(C)(C)C)C(=O)Nc1ccc(C)cn1>>CCOC[C@H](O)C(=O)Nc1ccc(C)cn1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20160108027A1,CC1(C)COC(C)(CCO)CN1.COc1cc(C(=O)O)cc2nc(NCc3cc(Cl)ccn3)oc12>>COc1cc(C(=O)N2CC(C)(CCO)OCC2(C)C)cc2nc(NCc3cc(Cl)ccn3)oc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04863920,II.O=C1c2c(Cl)cccc2-n2cncc2[C@@H]2CCCN12>>O=C1c2c(Cl)cccc2-n2cnc(I)c2[C@@H]2CCCN12,,CN(C)C=O,,,,test
US04080455,O=c1[nH]c(Cl)ncc1F.OCc1ccccc1>>O=c1[nH]c(OCc2ccccc2)ncc1F,,Cc1ccccc1,,[H-].[Na+],,test
US20040002485A1,CC(=O)c1ccc[nH]1.Fc1ccc(CBr)cc1>>CC(=O)c1cccn1Cc1ccc(F)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20030207877A1,CN1C(=O)Cn2cc(C(=O)NCc3ccc(Cl)cc3)c(=O)c3cc(CCl)cc1c32.CNCC(O)c1cc2ccccc2o1>>CN(Cc1cc2c3c(c1)c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn3CC(=O)N2C)CC(O)c1cc2ccccc2o1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,CN(C)C=O,test
US20050020654A1,COC(=O)c1cc(CC2SC(=O)NC2=O)ccc1O.CS(=O)(=O)OCCn1c(CCCCC2CCCCC2)nc2ccccc21>>COC(=O)c1cc(CC2SC(=O)NC2=O)ccc1OCCn1c(CCCCC2CCCCC2)nc2ccccc21,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20090018103A1,CCOC(COc1ccccc1Br)OCC>>Brc1cccc2ccoc12,,Clc1ccccc1,,CCOCC,[Na+].[OH-],test
US20140066426A1,CC(C)(C)CCNC(=O)OC(C)(C)C.CI>>CN(CCC(C)(C)C)C(=O)OC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US05536716,O=C1OC2(CCN(Cc3ccccc3)CC2)Cc2ccccc21>>O=C1OC2(CCNCC2)Cc2ccccc21,[Pd],CCO,,,,test
US20130085128A1,CCOC(=O)c1cc(O)nc2[nH]nc(C)c12.O=P(Br)(Br)Br>>CCOC(=O)c1cc(Br)nc2[nH]nc(C)c12,,Cc1ccccc1,O,CC(=O)[O-].[K+],,test
US05578607,Cc1cc(N)c(C)c2c(C#N)ccnc12.S=C(Oc1ccccn1)Oc1ccccn1>>Cc1cc(N=C=S)c(C)c2c(C#N)ccnc12,,ClCCl,,CN(C)c1ccccn1,,test
US06537948B1,COC(=O)C(C)Oc1nc(C)ncc1Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1[N+](=O)[O-]>>COC(=O)C(C)Oc1nc(C)ncc1Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1N,O=[Pt],CCOC(C)=O,,CCO,,test
US20080255114A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.CCC(O)CN>>CC(CCN)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,CN(C)C=O,,c1c[nH]cn1,,test
US04642308,Cc1cccc(O)c1.Nc1ccc2ccc(Cl)nc2n1>>Cc1cccc(Oc2ccc3ccc(N)nc3n2)c1,,CCOC(C)=O,,[K+].[OH-],,test
US20060105987A1,CC(O)=S.CCCCCCC/C=C\CCCCCBr>>CCCCCCC/C=C\CCCCCCC(O)=S,,CO,O,Cl,C[O-].[Na+],test
US20100292212A1,CC(C)N.O=C1N(c2ccc(OC(F)(F)F)cc2)CCC12CCN(S(=O)(=O)Cl)CC2>>CC(C)NS(=O)(=O)N1CCC2(CCN(c3ccc(OC(F)(F)F)cc3)C2=O)CC1,,ClCCl,,CCN(CC)CC,,test
US20060281914A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cl[SiH2]C(c1ccccc1)c1ccccc1.O=C1N[C@H](c2ccccc2)[C@@H]1O>>CC(C)(C)OC(=O)N1C(=O)[C@@H](O[SiH2]C(c2ccccc2)c2ccccc2)[C@H]1c1ccccc1,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20040171614A1,COC(=O)[C@H]1CC[C@@H](c2cccc(F)c2)N1.O=S(=O)(Cl)c1ccc(Cl)cc1>>COC(=O)[C@H]1CC[C@@H](c2cccc(F)c2)N1S(=O)(=O)c1ccc(Cl)cc1,,ClCCCl,,CCN(CC)CC,,test
US06211199B1,COc1cc(C(=O)N2CCCC(CCO)(c3ccc(Cl)c(Cl)c3)C2)cc(OC)c1OC.CS(=O)(=O)Cl>>COc1cc(C(=O)N2CCCC(CCOS(C)(=O)=O)(c3ccc(Cl)c(Cl)c3)C2)cc(OC)c1OC,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20050245554A1,CS(=O)(=O)c1nc(O)c(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1.OCc1ccc(F)c(F)c1>>Oc1nc(OCc2ccc(F)c(F)c2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20100004287A1,CC(=O)OCC(=O)NNC(=O)c1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)cc1>>CC(=O)OCc1nnc(-c2ccc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)cc2)o1,,C1CCOC1,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US20080153805A1,COC(=O)c1ccc2c(c1)N(S(=O)(=O)c1cc(C)ccc1OC)CCC2>>COc1ccc(C)cc1S(=O)(=O)N1CCCc2ccc(C(=O)O)cc21,,C1CCOC1,CO,O,[K+].[OH-],test
US20090203667A1,C1CCNCC1.O=C(O)c1ccc(C(F)(F)F)nc1Cl>>O=C(O)c1ccc(C(F)(F)F)nc1N1CCCCC1,,C1CCNCC1,,Cl,,test
US04855301,CC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(=O)OC(C)C.COC(=N)N>>COC1=NC(c2cccc([N+](=O)[O-])c2)C(C(=O)OC(C)C)=C(C)N1,,CN(C)C=O,O,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US20140329816A1,Clc1cc(-c2ccc(Cl)c(Cl)c2)ncn1.O=C(O)[C@H]1CCCN1>>O=C(O)[C@H]1CCCN1c1cc(-c2ccc(Cl)c(Cl)c2)ncn1,[Cu]I,CC(=O)N(C)C,CCOC(C)=O,Cl,O=C([O-])[O-].[K+].[K+],test
US20150158865A1,CN(C)C(=O)Cl.C[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@@H]1N>>C[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@@H]1NC(=O)N(C)C,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20100137322A1,Brc1cccc2c1C[C@H](N(Cc1ccccc1)Cc1ccccc1)CC2.CCOB(OCC)OCC>>OB(O)c1cccc2c1C[C@H](N(Cc1ccccc1)Cc1ccccc1)CC2,,C1CCOC1,,[Li]CCCC,,test
US05041455,CC/C=C/CCO.Clc1nsnc1-c1cccnc1>>CC/C=C/CCOc1nsnc1-c1cccnc1,,C1CCOC1,,O,[H-].[Na+],test
US20120214837A1,CC(=O)OC(C)=O.COC(=O)C(Cc1cnc2cccc(OC)c2c1)c1ccc(OC)c(OC)c1>>COC(=O)C(Cc1cnc2cccc(OC)c2c1)c1cc(OC)c(OC)cc1C(C)=O,,CCOCC,,,,test
US20110118230A1,CCNC(=O)OCC.C[C@H]1CN(Cc2ccc(Br)cc2F)C[C@@H](C)O1>>CCOc1cc(Br)ccc1CN1C[C@H](C)O[C@H](C)C1,,C1COCCO1,,[H-].[Na+],,test
US20050153977A1,CC(O)COC(C)(C)C.COC(=O)c1ccc(O)c(Cl)c1>>COC(=O)c1ccc(OC(C)COC(C)(C)C)c(Cl)c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020040138A1,COc1cc(Cl)cc(C(=O)C(F)(F)F)c1N>>Nc1c(O)cc(Cl)cc1C(=O)C(F)(F)F,,ClCCl,,BrB(Br)Br,O,test
US20140155381A1,Cc1noc(C)c1CO>>Cc1noc(C)c1C=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20120313058A1,C[SH-]C(=Nc1nc2ccccc2s1)[SH-]C.[2H]c1c([2H])c([2H])c(N)c(N)c1[2H]>>c1ccc2[nH]c(Nc3nc4ccccc4s3)nc2c1,,CN(C)C=O,,O,,test
US20160235716A1,C[C@H](NCc1ccc(F)cc1)C1CC1.O=C(Br)CBr>>C[C@@H](C1CC1)N(Cc1ccc(F)cc1)C(=O)CBr,,ClCCl,,,,test
US20080114002A1,CCOC(=O)CSc1ccc(Cl)cc1Sc1ccc(S(=O)(=O)CC)cc1Cl>>CCS(=O)(=O)c1ccc(Sc2cc(Cl)ccc2SCC(=O)O)c(Cl)c1,,CO,O,[Na+].[OH-],,test
US20070213397A1,CC(C)(C)OC(=O)NCCCNCc1c2ccccc2cc2ccccc12.Cl>>Cl.NCCCNCc1c2ccccc2cc2ccccc12,,CCO,,,,test
US20130338133A1,CC(C)[Si](Cl)(C(C)C)C(C)C.OCc1cc(F)ccc1Br>>CC(C)[Si](OCc1cc(F)ccc1Br)(C(C)C)C(C)C,CN(C)c1ccncc1,CN(C)C=O,,O,c1c[nH]cn1,test
US20080146559A1,c1ccc(C(c2ccccc2)(c2ccccc2)N2CCc3cc(OCCCN4CCCCC4)sc3C2)cc1>>c1c(OCCCN2CCCCC2)sc2c1CCNC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140045855A1,CC(C)(C)[S@](=O)N[C@]1(c2ccc(OC(F)(F)F)c(F)c2)CCOc2cccnc21.Cl>>Cl.N[C@]1(c2ccc(OC(F)(F)F)c(F)c2)CCOc2cccnc21,,CCO,,C1COCCO1,,test
US20140045828A1,NC1(CCO)c2cc(I)ccc2Oc2ncc(Br)cc21.O=C(N=C=S)c1ccc([N+](=O)[O-])cc1>>O=C(NC(=S)NC1(CCO)c2cc(I)ccc2Oc2ncc(Br)cc21)c1ccc([N+](=O)[O-])cc1,,C1CCOC1,,,,test
US05382380,CCCCCCCCCCBr.Oc1ccc(-c2ccc(Br)cc2F)cc1>>CCCCCCCCCCOc1ccc(-c2ccc(Br)cc2F)cc1,,CCC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20120184542A1,CC(NC(=O)c1ccc(Cl)c(N)c1)c1cccc(Cl)c1.O=C(O)c1cc2cnc(N3CCOCC3)nc2[nH]c1=O>>CC(NC(=O)c1ccc(Cl)c(NC(=O)c2cc3cnc(N4CCOCC4)nc3[nH]c2=O)c1)c1cccc(Cl)c1,,CN(C)C=O,ClCCl,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US07262201B1,CCOC(=O)CC(=O)c1ccc(OC)c(OC)c1.NN>>COc1ccc(C2=NNC(=O)C2)cc1OC,,CCO,,O,,test
US20070054935A1,Fc1ccc([Mg]Br)cc1.N#Cc1cccc(-c2ccncc2C=O)c1>>N#Cc1cccc(-c2ccncc2C(O)c2ccc(F)cc2)c1,,C1CCOC1,,,,test
US20010056179A1,CC(C)Oc1cccc2c1CCC(N)(C(=O)O)C2.O=C(OCC1c2ccccc2-c2ccccc21)ON1C(=O)CCC1=O>>CC(C)Oc1cccc2c1CCC(N)(C(=O)O)C2C(=O)OCC1c2ccccc2-c2ccccc21,,CC#N,O,CCN(CC)CC,,test
US05180419,CC(C)[C@](C)(N)C(N)=O.CCN(CC)CC.CCOC(=O)Cl.NC(=O)c1ccccc1C(=O)O>>CCN(CC)C(=O)c1ccc2c(c1C(=O)NC(C)(C(N)=O)C(C)C)OCO2,,C1CCOC1,O,,,test
US05360798,COC(=O)[C@@H]1C[C@@H](OS(C)(=O)=O)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1.SC(c1ccccc1)(c1ccccc1)c1ccccc1>>COC(=O)[C@@H]1C[C@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1,,CCOC(C)=O,CN(C)C=O,Cl,[H-].[Na+],test
US06130232,CC(C)(C)OC(=O)N1CCC(NC(=O)C(O)(c2ccccc2)C2CCCC2)CC1>>O=C(NC1CCNCC1)C(O)(c1ccccc1)C1CCCC1,,C1COCCO1,Cl,[Na+].[OH-],,test
US04477449,C1CSCN1.CCn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)nc21>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCSC3)nc21,,CN(C)C=O,,CCN(CC)CC,,test
US20040210063A1,CC(C)(C)OC(=O)NCCCNc1nc(N)c(C(=O)c2ccc(Cl)s2)s1.O=C(O)C(F)(F)F>>NCCCNc1nc(N)c(C(=O)c2ccc(Cl)s2)s1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20140275080A1,Nc1ccc(Oc2ccnc(Cl)c2)cn1.OB(O)c1cncnc1>>Nc1ccc(Oc2ccnc(-c3cncnc3)c2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US04146385,Clc1ccccc1.O=C(Cl)c1cccc([N+](=O)[O-])c1>>O=C(c1ccc(Cl)cc1)c1cccc([N+](=O)[O-])c1,,Clc1ccccc1,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20120196864A1,N#CCN.O=C=NC(=O)c1ccccc1>>N=C1CNC(=O)N1C(=O)c1ccccc1,,C1CCOC1,,,,test
US20090181942A1,CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2Cl)c2cc(Cl)ccc2NC1=O.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2Cl)c2cc(Cl)ccc2NC1=S,,C1CCOC1,CCOC(C)=O,O=C([O-])O.[Na+],,test
US20090181963A1,C1COCCN1.O=[N+]([O-])c1c(Cl)nc(Cl)nc1Cl>>O=[N+]([O-])c1c(Cl)nc(Cl)nc1N1CCOCC1,,ClCCl,,CCN(CC)CC,,test
US20110105461A1,C1COCCN1.Cc1ccc(S(=O)(=O)OCC2CCc3ccc(S(C)(=O)=O)cc3O2)cc1>>CS(=O)(=O)c1ccc2c(c1)OC(CN1CCOCC1)CC2,,CC#N,,,,test
US20090318431A1,Nc1ccccc1CCO.O=C(n1ccnc1)n1ccnc1>>O=C1Nc2ccccc2CCO1,,CC#N,,,,test
US05232940,N#CC(C#N)=C(C#N)C#N.NNc1c(Cl)cc(Cl)cc1Cl>>N#Cc1nn(-c2c(Cl)cc(Cl)cc2Cl)c(N)c1C#N,,CCO,,,,test
US05624600,CCCCCCCCI.O=C1O[C@H](c2ccccc2)CN1c1ccc(O)cc1>>CCCCCCCCOc1ccc(N2C[C@@H](c3ccccc3)OC2=O)cc1,,CN(C)C=O,,[H-].[Na+],,test
US05318966,CN=C=O.Cl.Oc1cccc2c1CC[C@H]1[C@@H]2CCN1CCC1CCCCC1>>CNC(=O)Oc1cccc2c1CC[C@H]1[C@@H]2CCN1CCC1CCCCC1.Cl,,CC#N,CCO,CCN(CC)CC,O=C([O-])O.[Na+],test
US03931177,CC(C)(C)N.O=C1CCC(c2ccc(OCC3CO3)c([N+](=O)[O-])c2)=NN1>>CC(C)(C)NCC(O)COc1ccc(C2=NNC(=O)CC2)cc1[N+](=O)[O-],,CO,,,,test
US20160039834A1,COCBr.Oc1cccc(Br)c1>>COCOc1cccc(Br)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20130079320A1,CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCCC1)c1ccc(C#N)cc1>>CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCCC1)c1ccc(CN)cc1,Cl[Ni]Cl,CCO,,O,[BH4-].[Na+],test
US20100216836A1,BrCC1COc2ccccc2O1.Oc1ccc(C2CCCNC2)cc1>>Oc1ccc(C2CCCN(CC3COc4ccccc4O3)C2)cc1,,CC#N,,Br,,test
US04785019,N#CCN.O=C(Cl)c1cccc2ccccc12>>N#CCNC(=O)c1cccc2ccccc12,,ClC(Cl)Cl,ClCCl,CCN(CC)CC,Cl,test
US06011028,COC1NCCCCC1Cc1ccccc1.[Cl-].[NH4+]>>Cl.N=C1NCCCCC1Cc1ccccc1,,CO,,,,test
US20080132477A1,C=CCN(C(=O)OC(C)(C)C)c1cccc(C(=O)OCC)c1>>C=CCN(C(=O)OC(C)(C)C)c1cccc(C(=O)O)c1,,CCO,,Cl,[Li+].[OH-],test
US20160122342A1,CCN(c1cccc2c1CC=CCCc1cc(C)nc(OC)c1CNC2=O)C1CC2(CC(NC(=O)OC(C)(C)C)C2)C1>>CCN(c1cccc2c1CC=CCCc1cc(C)[nH]c(=O)c1CNC2=O)C1CC2(CC(N)C2)C1,,C1COCCO1,CO,Cl,,test
US20120264923A1,COC(=O)C=C(C)CCCC(C)CCCC(C)C.OCC(O)CO>>CC(=CC(=O)OCC(O)CO)CCCC(C)CCCC(C)C,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20130116245A1,CC[C@H]1CN(C2COC2)CCN1c1ccc(Nc2cc(-c3cc(F)cc(-n4ccn5c6c(cc5c4=O)CCCC6)c3C=O)cn(C)c2=O)nc1>>CC[C@H]1CN(C2COC2)CCN1c1ccc(Nc2cc(-c3cc(F)cc(-n4ccn5c6c(cc5c4=O)CCCC6)c3CO)cn(C)c2=O)nc1,,CO,,[BH4-].[Na+],,test
US20040053908A1,COCCOc1cc2nccc(Oc3ccc(NC(=O)Oc4ccccc4)c(Cl)c3)c2cc1C(=O)OC.NC1CC1>>COCCOc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(=O)OC,,O,,CN(C)C=O,,test
US05488118,COC(=O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)[C@H](OS(=O)(=O)c1ccc(C)cc1)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1,CN(C)c1ccccn1,O,c1ccncc1,,,test
US05162326,CC(C)(C)C(=O)OCI.CCCOc1cc(=O)n(CCC)c(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1>>CCCOc1cc(=O)n(CCC)c(=O)n1Cc1ccc(-c2ccccc2-c2nnnn2COC(=O)C(C)(C)C)cc1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20110144105A1,CC(C)(C)NC(=O)c1cnc2[nH]c(C(CC3CCCC3)c3ccc(S(C)(=O)=O)cc3)cc2c1>>CS(=O)(=O)c1ccc(C(CC2CCCC2)c2cc3cc(C#N)cnc3[nH]2)cc1,,ClC(Cl)Cl,,O=P(Cl)(Cl)Cl,,test
US20130261106A1,CC(C)(C)OC(=O)N1CCCC12CCNC2.CC(C)Oc1cc(F)ccc1[N+](=O)[O-]>>CC(C)Oc1cc(N2CCC3(CCCN3C(=O)OC(C)(C)C)C2)ccc1[N+](=O)[O-],,CS(C)=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US03959273,CCOc1ccccc1OCC1CNCCO1>>CCOc1ccccc1OCC1CNCCO1,,O,,Cl,[Na+].[OH-],test
US03939148,O=C(OC(=O)C(F)(F)F)C(F)(F)F.O=[N+]([O-])O>>O=C(OC(=O)C(F)(F)F)C(F)(F)F.O=[N+]([O-])O,,C[N+](=O)[O-],,,,test
US20030045532A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=c1[nH]c2c(-c3ccccc3F)nnn2c2ccccc12>>Cc1ccc(S(=O)(=O)Oc2nc3c(-c4ccccc4F)nnn3c3ccccc23)cc1,,CN(C)C=O,O,CCN(CC)CC,,test
US20070032478A1,O=C(c1ccc([N+](=O)[O-])cc1)c1ccc(C(C(=O)[O-])C(=O)[O-])c([N+](=O)[O-])c1>>Nc1ccc(C(=O)c2ccc3c(c2)NC(=O)C3)cc1,,CCO,ClC(Cl)Cl,Cl,,test
US05208222,C=CC(C)CO.CC(C)(C)[Si](C)(C)Cl>>C=CC(C)CO[Si](C)(C)C(C)(C)C,,CN(C)C=O,ClCCl,O,c1c[nH]cn1,test
US04824958,CC(C)N=C(O)N(C(C)C)C(C)C.COC(=O)c1sc(C)cc1O>>COC(=O)c1sc(C)cc1OC(C)C,,CC#N,,,,test
US20080207721A1,CC(C)(C(O)c1ccccc1)[N+](=O)[O-]>>CC(C)(N)C(O)c1ccccc1,[Zn],CCO,O,Cl,,test
US20080293780A1,CC(=O)NC1Cc2ccc(S(N)(=O)=O)cc2C1.FC(F)(F)c1nnc(Cl)s1>>CC(=O)NC1Cc2ccc(S(=O)(=O)Nc3nnc(C(F)(F)F)s3)cc2C1,,CN1CCCC1=O,O,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20130266645A1,CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](N=[N+]=[N-])CC[C@]4(C)[C@H]3CC[C@]12C>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](N)CC[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,CCOCC,[Al+3].[H-].[H-].[H-].[H-].[Li+],[Cl-].[NH4+],test
US04477447,CON=C(C(=O)NC1C(=O)N2C(C(=O)OC(COC(C)C)COC(C)C)C=CS[C@H]12)c1csc(NC=O)n1.O=C(OO)c1cccc(Cl)c1>>CON=C(C(=O)NC1C(=O)N2C(C(=O)OC(COC(C)C)COC(C)C)=CCS(=O)[C@H]12)c1csc(NC=O)n1,,ClCCl,,CSC,,test
US20090062252A1,CC(C)(C)OC(=O)N1CCN[C@@H](CO)C1.Cc1c(-c2ccc(C(=O)O)s2)noc1C(F)(F)F.Cl>>Cc1c(-c2ccc(C(=O)N3CCNC[C@@H]3CO)s2)noc1C(F)(F)F.Cl,,C1COCCO1,,,,test
US20040014972A1,O=C(CCCN1CCN(c2cccc3cccnc23)CC1)c1ccc(F)cc1.O=C(O)/C=C/C(=O)O>>O=C(O)/C=C/C(=O)O.OC(CCCN1CCN(c2cccc3cccnc23)CC1)c1ccc(F)cc1,,CCO,CO,[BH4-].[Na+],,test
US20100292188A1,CC(=O)Cl.c1cc(-c2nc3c(s2)CNCC3)ccc1O[C@@H]1C[C@@H](N2CCCCC2)C1>>CC(=O)N1CCc2nc(-c3ccc(O[C@@H]4C[C@@H](N5CCCCC5)C4)cc3)sc2C1,,ClCCl,,CCN(CC)CC,,test
US05187185,Cc1ccc(C)n1-c1c(Cl)cc(C(F)(F)F)cc1Cl.FC(Cl)(Cl)SCl>>Cc1cc(SC(F)(Cl)Cl)c(C)n1-c1c(Cl)cc(C(F)(F)F)cc1Cl,,ClCCl,,,,test
US20120115811A1,CC(C)(C)OC(=O)CBr.N[C@@H](Cc1ccc(F)cc1)C(=O)Nc1cccc(-c2ccncc2)c1>>CC(C)(C)OC(=O)CN[C@@H](Cc1ccccc1)C(=O)Nc1cccc(-c2ccncc2)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20030221948A1,C=CC.CC(C)=O.Oc1ccccc1.c1ccccc1>>CC(C)c1ccccc1.Oc1ccccc1,,CC(C)=O,,,,test
US20130225554A1,CC(C)(C)OC(=O)n1cnc(CONC(=O)[C@@H]2CC[C@@H]3CN2C(=O)N3OCc2ccccc2)c1>>CC(C)(C)OC(=O)n1cnc(CONC(=O)[C@@H]2CC[C@@H]3CN2C(=O)N3O)c1,[Pd],CO,,,,test
US20120101127A1,C=C(C)C.COC(=O)c1ccccc1N.O=Cc1cccc(Br)c1>>COC(=O)c1cccc2c1NC(c1cccc(Br)c1)CC2(C)C,,CC#N,CCOC(C)=O,O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3],,test
US20090253751A1,CC(=O)c1c(C)nn(-c2ccc(C)c(C)c2)c1O.CC(C)NC(=O)c1ccc(C(=O)NN)s1>>CC1=NN(c2ccc(C)c(C)c2)C(=O)C1=C(C)NNC(=O)c1ccc(C(=O)NC(C)C)s1,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20060052315A1,CNCC(O)c1ccccc1.O=C(O)c1ccc(-c2ccccc2C(F)(F)F)cc1>>CN(CC(O)c1ccccc1)C(=O)c1ccc(-c2ccccc2C(F)(F)F)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020193367A1,CCCN(C)c1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3cc(C)no3)c2)cc1C>>CCCN(C)c1cc2c(cc1C)NC(=O)CC(c1cccc(-c3cc(C)no3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060106096A1,COc1ccc(N=C=O)cc1.Cl.Nc1ccc2cc(C(=O)N[C@H]3CN4CCC3CC4)sc2c1>>COc1ccc(NC(=O)Nc2ccc3cc(C(=O)N[C@H]4CN5CCC4CC5)sc3c2)cc1.Cl,,C1CCOC1,,CCN(CC)CC,Cl,test
US20050143422A1,CC(=O)Cl.CC(C)[C@H](NS(=O)(=O)c1ccc(-c2ccc(NC(=O)c3cc4cc(N)ccc4o3)cc2)cc1)C(=O)O>>CC(=O)Nc1ccc2oc(C(=O)Nc3ccc(-c4ccc(S(=O)(=O)N[C@H](C(=O)O)C(C)C)cc4)cc3)cc2c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20060173036A1,CCCCN.O=[N+]([O-])c1ccc(Cl)nc1NCCCN1CCCCC1>>CCCCNc1ccc([N+](=O)[O-])c(NCCCN2CCCCC2)n1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05453497,COc1cc(C(=O)Cl)cc(OC)c1OC.Nc1nc(=O)[nH]cc1F>>COc1cc(C(=O)Nc2nc(=O)[nH]cc2F)cc(OC)c1OC,,c1ccncc1,,O,,test
US20110053891A1,Nc1nc(=O)n(CC2CC2)cc1F.O=C=Nc1ccccc1Cl>>O=C(Nc1ccccc1Cl)Nc1nc(=O)n(CC2CC2)cc1F,,CC#N,,,,test
US20010001799A1,CCOC(=O)COc1ccccc1C(Nc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)C(=O)OCC>>N=C(N)c1ccc(NC(C(=O)O)c2ccccc2OCC(=O)O)cc1,,C1CCOC1,,[Li+].[OH-],,test
US20100305096A1,CC1(C)CNCCN1CCS(C)(=O)=O.CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CCl)n(C)c2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCN(CCS(C)(=O)=O)C(C)(C)C3)n(C)c2n1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20090143357A1,CC(=O)C=NO.N#CC(N)C#N>>Cc1c[n+]([O-])c(N)c(C#N)n1,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20150141406A1,COc1nccc2c1c(-c1ccc(CC#N)cc1)nn2-c1c(F)cccc1F.O=C1CCC(=O)N1Br>>COc1ncc(Br)c2c1c(-c1ccc(CC#N)cc1)nn2-c1c(F)cccc1F,,CN(C)C=O,,O,,test
US04940710,C=O.O=C(O)c1cn(C2CC2)c2cc(N3CCNC(c4ccco4)C3)c(F)cc2c1=O>>CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1c1ccco1,,O=CO,,,,test
US04156778,C[C@H]1CNC(c2ccc(N)c([N+](=O)[O-])c2)=N1.Cl>>C[C@H]1CNC(c2ccc(N)c(N)c2)=N1.Cl,[Ni],CO,,,,test
US05556864,Clc1ccccc1C=CC=Cc1ccccc1OCc1ccccc1>>Clc1ccccc1CCCCc1ccccc1OCc1ccccc1,,C1CCOC1,CCO,,,test
US20040097518A1,C[C@H](NC(=O)c1c(CN2CCN(C(=O)OC(C)(C)C)CC2)c(-c2ccccc2)nc2ccc(F)cc12)C1CCCCC1>>C[C@H](NC(=O)c1c(CN2CCNCC2)c(-c2ccccc2)nc2ccc(F)cc12)C1CCCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100064450A1,C=O.CNC.O=Cc1ccc(O)c(Br)c1>>CN(C)Cc1cc(C=O)cc(Br)c1O,,CCO,,,,test
US20110295017A1,O=C1CC(Br)C(=O)N1.c1ccc(-c2c3ccccc3cc3ccccc23)cc1>>Brc1c2ccccc2c(-c2ccccc2)c2ccccc12,,CN(C)C=O,,,,test
US20140329797A1,CC(C)(c1ccc(-c2noc(-c3ccc(=O)n(Cc4cccc(C(=O)O)c4)n3)n2)cc1)C(F)(F)F.O=C(Cl)C(=O)Cl>>CC(C)(c1ccc(-c2noc(-c3ccc(=O)n(Cc4cccc(C(=O)Cl)c4)n3)n2)cc1)C(F)(F)F,CN(C)C=O,ClCCl,,,,test
US20090306062A1,CC(=O)O.C[C@@H]1COCC[C@@H]1C#N>>C[C@@H]1COCC[C@@H]1C(=O)O,,Cl,,,,test
US04117164,CC(C)(O)C#N.O=C1C=CCCc2ccc([N+](=O)[O-])cc21>>N#CC1CCc2ccc([N+](=O)[O-])cc2C(=O)C1,,C1CCOC1,,CO,O=C([O-])[O-].[K+].[K+],test
US20050234042A1,CC(C)(C)OC(=O)NC(C(=O)N1CCC[C@H]1c1nnn(Cc2ccccc2)n1)C1CCCCC1.O=C(O)C(F)(F)F>>NC(C(=O)N1CCC[C@H]1c1nnn(Cc2ccccc2)n1)C1CCCCC1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20160271142A1,COc1cc2c(cc1OCc1ccccc1)N(COCC[Si](C)(C)C)C(=O)C1CC(=O)CN1C2=O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1cc2c(cc1OCc1ccccc1)N(COCC[Si](C)(C)C)C(=O)C1CC(OS(=O)(=O)C(F)(F)F)=CN1C2=O,,ClCCl,,Cc1cccc(C)n1,,test
US20070082912A1,CC(=O)CCC(=O)c1cc(Br)ccc1OCc1ccc(F)cc1.Nc1cc(C(=O)O)ccc1F>>Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2)n1-c1cc(C(=O)O)ccc1F,,CCOC(C)=O,CN1CCCC1=O,Cc1ccc(S(=O)(=O)O)cc1,,test
US20160139158A1,CCN(C(C)=O)c1cc(OCc2ccccc2)ccc1OC.CO>>CCN(CC)c1cc(OCc2ccccc2)c(C=O)cc1OC,,C1CCOC1,,,,test
US20130225620A1,C=C(OCC)c1cc(F)cc2c1cnn2C>>CC(=O)c1cc(F)cc2c1cnn2C,,C1CCOC1,Cl,O,,test
US06482986B1,CC(=O)c1ccc(C2CC(C)(C)CC(C)(C)C2)cc1.ClCl>>CC(=O)c1ccc(C2CC(C)(C)CC(C)(C)C2)c(Cl)c1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20150031667A1,CC(=O)O.CCOC(=O)c1cnn2ccc(N3C[C@H](O)C[C@@H]3c3cccc(F)c3)nc12>>CCOC(=O)c1cnn2ccc(N3C[C@@H](OC(C)=O)C[C@@H]3c3cccc(F)c3)nc12,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100135999A1,CCOC(=O)N1CCN(C(=O)[C@@H](N)CCC(=O)OC(C)(C)C)CC1.Cc1ccc2c(O)cc(C(=O)O)nc2c1>>CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(O)c3ccc(C)cc3n2)CC1,,CN(C)C=O,O,ClCCCl,On1nnc2ccccc21,test
US20050131014A1,COc1ccc(B(O)O)cc1.O=C(c1ccccc1)c1cnc2c(C(F)(F)F)cccc2c1OS(=O)(=O)C(F)(F)F>>COc1ccc(-c2c(C(=O)c3ccccc3)cnc3c(C(F)(F)F)cccc23)cc1,,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US06331548B1,COC(=O)Cl.O=C(Nc1c(Cl)cccc1Cl)c1cn([C@H]2CCNC2)c2ncccc2c1=O>>COC(=O)N1CC[C@H](n2cc(C(=O)Nc3c(Cl)cccc3Cl)c(=O)c3cccnc32)C1,,ClCCl,,CCN(CC)CC,,test
US05462942,ClCCN1CCN(c2cc(Cl)cc3c2OCCO3)CC1.O=C1NS(=O)(=O)c2ccccc21>>Cl.O=C1c2ccccc2S(=O)(=O)N1CCN1CCN(c2cc(Cl)cc3c2OCCO3)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20090124601A1,CC1(C)OC(=O)C(C(=O)Cc2cc(F)c(F)cc2F)C(=O)O1.O=C1NCCCNC1CC(F)(F)F>>O=C(CC(=O)N1CCCNC(=O)C1CC(F)(F)F)Cc1cc(F)c(F)cc1F,,CC#N,,CCN(C(C)C)C(C)C,,test
US20040198778A1,O=C(Br)CBr.O=C1N[C@H](Cc2ccccc2)CO1>>O=C(CBr)N1C(=O)OC[C@H]1Cc1ccccc1,,C1CCOC1,CCOC(C)=O,CCCCCC,[Li]CCCC,test
US20110021568A1,CCC(C)C(N=[N+]=[N-])C(=O)N(COC(=O)CC(C)C)C(CC(OC(C)=O)c1nc(C(=O)NC(Cc2ccccc2)CC(C)C(=O)O)cs1)C(C)C.CN(C)CC(=O)Oc1c(F)c(F)c(F)c(F)c1F>>CCC(C)C(NC(=O)CN(C)C)C(=O)N(COC(=O)CC(C)C)C(CC(OC(C)=O)c1nc(C(=O)NC(Cc2ccccc2)CC(C)C(=O)O)cs1)C(C)C,[Pd],CCOC(C)=O,,,,test
US20130109662A1,C=C1CC(=O)O1.NC1CCC1>>CC(=O)CC(=O)NC1CCC1,,C1CCOC1,,,,test
US20080293770A1,CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3cc(F)c(Br)cc32)CC1>>O=c1[nH]c2cc(F)c(Br)cc2n1C1CCNCC1,,CCO,,Cl,,test
US20080008965A1,CC(=O)OC(C)=O.OC1OC2CC3CC1C2C3>>CC(=O)OC1OC2CC3CC2C1C3,,c1ccncc1,,,,test
US05739387,COC(=O)[C@H]1N=C(c2ccccc2)O[C@@H]1c1ccc2c(c1)OC(C)(C)O2>>N[C@H](C(=O)O)[C@H](O)c1ccc(O)c(O)c1,,Cl,,,,test
US04323681,N#Cc1cnc(N)nc1N.S>>NC(=S)c1cnc(N)nc1N,,CS(C)=O,O,CCN(CC)CC,c1ccncc1,test
US20060173018A1,Cc1ccc2c(N3CCN(C(=O)[C@@H](O)CC(C)C)CC3)nc(-c3ccccc3O)nc2c1.Cl>>Cc1ccc2c(N3CCN(C(=O)[C@@H](O)CC(C)C)CC3)nc(-c3ccccc3O)nc2c1.Cl,,ClCCl,,CCOCC,,test
US20160108039A1,COCC1COC(C)(CCO)CN1.COc1cc(C(=O)O)cn2nc(NCc3cccc(Cl)c3)nc12>>COCC1COC(C)(CCO)CN1C(=O)c1cc(OC)c2nc(NCc3cccc(Cl)c3)nn2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140018361A1,CN(C)C1CCC(N)CC1.Clc1nc(Cl)c2cc[nH]c2n1>>CN(C)C1CCC(Nc2nc(Cl)nc3[nH]ccc23)CC1,,CC(C)(C)O,,CCN(CC)CC,Cl,test
US06376490B1,COCC(=O)Cl.COc1nc2cc(C)c(Cl)c(N)c2nc1OC>>COCC(=O)Nc1c(Cl)c(C)cc2nc(OC)c(OC)nc12,,ClCCl,,c1ccncc1,,test
US20080119468A1,COC(=O)c1ccc(C)c(-c2ccc3c(C(C)C(F)(F)F)nncc3c2)c1>>Cc1ccc(C(=O)O)cc1-c1ccc2c(C(C)C(F)(F)F)nncc2c1,,C1CCOC1,CO,,,test
US05132424,CC#N.CCOC(=O)c1ccc(OCC)cc1>>CCOc1ccc(C(=O)CC#N)cc1,,Cc1ccccc1,O,C,C[O-].[Na+],test
US04959482,CC(C)(C)c1cc(NC(=O)CCCCCl)cc(C(C)(C)C)c1O>>CC(C)(C)c1cc(N2CCCCC2=O)cc(C(C)(C)C)c1O,,C1CCOC1,,[H-].[Na+],,test
US20160244414A1,CN(C)C=NC(=O)c1cn(-c2ccccc2)c(=O)cc1Oc1ccccc1.NN>>O=c1cc(Oc2ccccc2)c(-c2nc[nH]n2)cn1-c1ccccc1,,CC(=O)O,,O,,test
US20040053941A1,CCO[C@H]1CNC[C@H]1Nc1nc(CC)cnc1CC.COC(=O)Cl>>CCO[C@H]1CN(C(=O)OC)C[C@H]1Nc1nc(CC)cnc1CC,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20110313196A1,CCc1cc(/C=C/C(N)=O)ccc1Cl>>CCc1cc(CCC(N)=O)ccc1Cl,[Ni],CCO,,,,test
US20150119394A1,CCOC(=O)c1c(S(=O)(=O)N2CCO[C@H](COc3cccc(-c4ccccc4)c3)C2)c2cc(Cl)ccc2n1S(=O)(=O)c1ccccc1.N>>NC(=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)N1CCO[C@H](COc2cccc(-c3ccccc3)c2)C1,,CC(C)O,,,,test
US20060160864A1,CCCCOCCOc1ccc(-c2ccc(N3CCCCCCC3)c(/C=C/C(=O)OCC)c2)cc1>>CCCCOCCOc1ccc(-c2ccc(N3CCCCCCC3)c(/C=C/C(=O)O)c2)cc1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20050004364A1,CCOc1ccc2[nH]cc(C(=O)O)c(=O)c2n1.NCc1ccccc1>>CCOc1ccc2[nH]cc(C(=O)NCc3ccccc3)c(=O)c2n1,,CN(C)C=O,O,,,test
US04628059,NCc1cccc(F)c1.S=C(Cl)Cl>>Fc1cccc(CN=C=S)c1,,C1CCOC1,,CCN(CC)CC,,test
US20150336935A1,COc1cc(C)cc(C(=O)[C@H]2[C@@H](C)[C@H](O)C[C@H]3C(C)(C)CCC[C@]23C)c1>>COc1cc(C)cc(C(=O)[C@H]2[C@@H](C)C(=O)C[C@H]3C(C)(C)CCC[C@]23C)c1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20090048239A1,COC(CN(C)S(=O)(=O)NC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)C[C@H](OCCN(C)Cc1ccccc1)COc1ccccc1-3)OC>>CNCCO[C@@H]1COc2ccccc2-c2c(C3CCCCC3)c3ccc(C(=O)NS(=O)(=O)N(C)CC(OC)OC)cc3n2C1,[Pd],CO,,,,test
US20110124626A1,CC(=O)c1ccc2c(c1)CCNCC2.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(=O)c1ccc2c(c1)CCN(C(=O)OC(C)(C)C)CC2,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20030045523A1,O=C1C(=Cc2cccnc2)N2CCC1CC2>>OC1C2CCN(CC2)C1Cc1cccnc1,[Ni],CO,,,,test
US20090298823A1,CN(C(=O)COCc1ccccc1)c1ccc([N+](=O)[O-])cc1>>CN(C(=O)COCc1ccccc1)c1ccc(N)cc1,[Fe],CCO,O,O=C[O-].[NH4+],,test
US06653346B1,Cc1c(OCC(=O)c2ccccc2)ccc(OCC(=O)c2ccccc2)c1C.O=C(CBr)c1ccccc1>>Cc1c(C)c2occ(-c3ccccc3)c2c2c(-c3ccccc3)coc12,,Cc1ccccc1C,,O,,test
US20140329733A1,CCCCCC(C)O.O=C(O)C1CC1>>CCCCCC(C)OC(=O)C1CC1,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,,,test
US20100010007A1,CCOC(=O)c1csc(C2CCN(C(=O)OCc3ccccc3)CC2)n1>>CCOC(=O)c1csc(C2CCNCC2)n1,,CC(=O)O,CCOCC,Br,,test
US05276168,CC1(C)CC(Br)c2cc(C#N)ccc2O1.NCCNc1ccccc1>>CC1(C)CC(NCCNc2ccccc2)c2cc(C#N)ccc2O1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20090143353A1,COc1c(Br)c(I)c(C)c(C#N)c1NC(=O)C(F)(F)F.c1ccc(B2OCCCO2)cc1>>COc1c(Br)c(-c2ccccc2)c(C)c(C#N)c1NC(=O)C(F)(F)F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US04440788,CCNC(=O)[C@H](CSCC)NC(=O)OC(C)(C)C.Cl>>CCNC(=O)[C@@H](N)CSCC.Cl,,CCOC(C)=O,,,,test
US07034039B2,CCOC(=O)c1c(O)c2ccc(Cl)cc2c(=O)n1C.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1c(OS(=O)(=O)C(F)(F)F)c2ccc(Cl)cc2c(=O)n1C,,C1CCOC1,,O,[H-].[Na+],test
US20130158057A1,CNc1nc(Nc2ccc(Br)cc2OC)ncc1C(F)(F)F.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>CNc1nc(Nc2ccc(-c3cnn(C)c3)cc2OC)ncc1C(F)(F)F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20140038941A1,CC(C)c1nc2cc(C(=O)O)c(Cl)cn2c1S(=O)(=O)O.CC(Cl)Cl.CCN(CC)CC.Nc1ccccc1>>CC(C)c1nc2cc(C(=O)Nc3ccccc3)c(Cl)cn2c1S(=O)(=O)Nc1ccccc1,,CC(Cl)Cl,,O=P(Cl)(Cl)Cl,O=C([O-])O.[Na+],test
US04324893,CCN.CCOC(=O)c1c(N2CCCC2)c2ccc(C)nc2n(CC)c1=O>>CCNc1c(C(=O)OCC)c(=O)n(CC)c2nc(C)ccc12,,O,,CCO,,test
US04450155,CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)NCCc1ccccc1.Cl>>Cl.O=C(NCCc1ccccc1)[C@@H]1CCCN1,,CCOCC,,CCOC(C)=O,,test
US04410521,COc1ccc(C(=O)c2ccc(C)cc2)cc1.O=C1CCC(=O)N1Br>>COc1ccc(C(=O)c2ccc(CBr)cc2)cc1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20090306076A1,CC(C)CN(Cc1ccc2c(c1)C(OC1CCCCO1)CCCC2)C(=O)C1CN(C(=O)OC(C)(C)C)CCO1>>CC(C)CN(Cc1ccc2c(c1)C(O)CCCC2)C(=O)C1CN(C(=O)OC(C)(C)C)CCO1,,CCO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US07569659B1,Nc1ccn(CC(=O)OC(=O)c2ccccc2)c(=O)n1.O=C(Cl)c1ccccc1>>O=C(O)Cn1ccc(NC(=O)c2ccccc2)nc1=O,,c1ccncc1,,,,test
US20110152260A1,CC(C)(C)[Si](C)(C)Cl.Nc1nc2cc(CO)ccc2n1C1CCCCC1>>CC(C)(C)[Si](C)(C)OCc1ccc2c(c1)nc(N)n2C1CCCCC1,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US06268490B1,Cc1cn([C@@H]2O[C@@]3(CO[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)CO[C@@H]2[C@@H]3OCc2ccccc2)c(=O)[nH]c1=O>>Cc1cn([C@@H]2O[C@@]3(CO)CO[C@@H]2[C@@H]3OCc2ccccc2)c(=O)[nH]c1=O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04992433,N#CCCNc1cccc(C(F)(F)F)c1>>NCCCNc1cccc(C(F)(F)F)c1,[Ni],CO,,N,[H][H],test
US20120329780A1,COc1cc(N)ccc1N1CCOCC1.COc1ccc(Cn2cc3nc(-c4cccc(S(N)(=O)=O)c4)nc(Cl)c3n2)cc1>>COc1cc(Nc2nc(-c3cccc(S(N)(=O)=O)c3)nc3cn[nH]c23)ccc1N1CCOCC1,C1COCCO1,CO,,Cl,,test
US20140094474A1,CCOC(=O)c1c[nH]c(C)n1.C[C@@H]1CO1>>CCOC(=O)c1cn(C[C@@H](C)O)c(C)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06194487B1,O=C(Cl)CCCCC(=O)Cl.OCCCCCCO>>O=C(Cl)CCCCC(=O)Cl.OCCCCCCO,,CCN(CC)CC,,,,test
US20110212946A1,N#CC(c1ccccc1)C1(O)CCOCC1>>N#CC(=C1CCOCC1)c1ccccc1,,c1ccncc1,,O=S(Cl)Cl,,test
US20150133538A1,CI.Cc1ccc(O)c(C)c1>>COc1ccc(C)cc1C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100256097A1,NO.O=Cc1cc(Br)sc1[N+](=O)[O-]>>O=[N+]([O-])c1sc(Br)cc1C=NO,,CCO,,Cl,CC(=O)[O-].[Na+],test
US06255306B1,CCOC(=O)c1cc2c(N3CCN(C)CC3)cccc2n1C>>CN1CCN(c2cccc3c2cc(C(=O)O)n3C)CC1,,C1CCOC1,O,[Li+].[OH-],,test
US04725680,CC(Cl)OC(=O)Oc1cccc2c1OC(C)(C)C2.c1ccncc1>>CNC(=O)Oc1cccc2c1OC(C)(C)C2,,c1ccncc1,,CN(C)c1ccccc1,,test
US20040063786A1,CO.Cc1ccc(CC#N)cc1C.O=S(=O)(O)O>>COC(=O)Cc1ccc(C)c(C)c1,,O,,,,test
US20010000513A1,COC(=O)CCC(=O)c1ccc(Br)cc1.OB(O)c1cccc(F)c1>>COC(=O)CCC(=O)c1ccc(-c2cccc(F)c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20050239827A1,Clc1nc(Cl)nc(Cl)n1.Nc1ccc(NC(=O)c2ccc(F)cc2O)c(OCc2ccccc2)c1>>O=C(Nc1ccc(Nc2nc(Cl)nc(Cl)n2)cc1OCc1ccccc1)c1ccc(F)cc1O,,C1CCOC1,,O=C([O-])O.[Na+],,test
US04876354,O=C(O)[C@@H](O)[C@H](O)C(=O)O.OC1(C(c2cccc(Cl)c2)n2ccnc2)C2CC3CC(C2)CC1C3>>O=C(O)C(O)C(O)C(=O)O.OC1(C(c2cccc(Cl)c2)n2ccnc2)C2CC3CC(C2)CC1C3,,CC#N,CO,,,test
US20120238574A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc([N+](=O)[O-])cc2Br)CC1>>O=[N+]([O-])c1ccc(OC2CCNCC2)c(Br)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05075302,CC(=O)SC[C@@H](Cc1ccccc1C)C(=O)O.O=C1CCCCCN1.Oc1cccc2[nH]nnc12>>CC(=O)SC[C@@H](Cc1ccccc1C)C(=O)[C@H]1CCCNC(=O)C1N,,CN(C)C=O,,CCN=C=NCCCN(C)C,Cl,test
US20100331326A1,Cc1ccncc1N1CCNC1=O.Cn1cc2cc(Br)ccc2n1>>Cc1ccncc1N1CCN(c2ccc3nn(C)cc3c2)C1=O,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20130131045A1,CCOC(=O)CCC(O[Si](C)(C)C)c1cc(Cl)ccc1[N+](=O)[O-]>>CCOC(=O)CCC(O)c1cc(Cl)ccc1[N+](=O)[O-],,CCO,O,O=C(O)CC(O)(CC(=O)O)C(=O)O,,test
US20100087427A1,CC(C)(C)OC(=O)N1C[C@H](CN(Cc2ccccc2O)c2ccc(Cl)cc2)[C@@H](Cc2ccccc2)C1.COCCCBr>>COCCCOc1ccccc1CN(C[C@H]1CN(C(=O)OC(C)(C)C)C[C@@H]1Cc1ccccc1)c1ccc(Cl)cc1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US05681940,CC1(CO[Si](C)(C)C(C)(C)C)CN([C@@]2(N)C[C@@](O)([Si](C)(C)C(C)(C)C)[C@@H](C(O)[Si](C)(C)C(C)(C)C)O2)C(=O)NC1=O>>Cc1cn([C@@]2(N)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06232310B1,CC(=O)Nc1ccc(Cl)cc1S(=O)(=O)CC#N>>CC1=C(C#N)S(=O)(=O)c2cc(Cl)ccc2N1,,[Na+],[OH-],C,,test
US20160175289A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.CC(F)(CO)CO>>CC(F)(CO)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,ClC(Cl)Cl,,c1c[nH]cn1,,test
US20060030583A1,O=C(c1cccc(-c2cnc3[nH]ccc3c2)c1)N1CCOCC1.O=C1CCC(=O)N1I>>O=C(c1cccc(-c2cnc3[nH]cc(I)c3c2)c1)N1CCOCC1,,CC(C)=O,,,,test
US05889026,ClCC1CO1.OC1(Cc2ccccc2)CCNCC1>>OC(CCl)CN1CCC(O)(Cc2ccccc2)CC1,,CCOCC,ClCCl,O,,test
US20150232463A1,CC(C)(C(=O)O)c1ccc(F)cc1>>CC(C)(CO)c1ccc(F)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080293684A1,NC(=O)c1cccc(Br)c1.OCc1cccc(B(O)O)c1>>NC(=O)c1cccc(-c2cccc(CO)c2)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CO,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],,test
US04628057,ClCc1ccccn1.O=C(O)C1Cc2c([nH]c3ccccc23)CN1.S=C=S>>O=C(O)C1Cc2c([nH]c3ccccc23)CN1C(=S)SCc1ccccn1,,CCO,,Cl,[K+].[OH-],test
US20040106800A1,CNC.Clc1ccc(C2=NNCC2c2ccccc2)cc1.O=C=NS(=O)(=O)Cl>>CN(C)S(=O)(=O)NC(=O)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1,,ClCCl,,,,test
US05602077,C#CCBr.Cn1c(C(F)(F)F)cc(=O)n(-c2cc(O)c(Cl)cc2F)c1=O>>C#CCOc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl,,CC#N,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],,test
US20100063066A1,CC(C)(C)OC(=O)n1nc(CCCO[Si](C)(C)C(C)(C)C)c2c(Nc3c(-c4ncccn4)oc4cnccc34)ccc(Cl)c21>>CC(C)(C)OC(=O)n1nc(CCCO)c2c(Nc3c(-c4ncccn4)oc4cnccc34)ccc(Cl)c21,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120214762A1,C#C[Si](C)(C)C.CC(=O)c1ccncn1>>CC(O)(C#C[Si](C)(C)C)c1ccncn1,,C1CCOC1,O,[Li]CCCC,,test
US20030039838A1,CC(C)OB(OC(C)C)OC(C)C.CCCCCCCCC1(CCCCCCCC)c2ccccc2-c2ccc(Br)cc21>>CCCCCCCCC1(CCCCCCCC)c2ccccc2-c2ccc(B(O)O)cc21,,C1CCOC1,,[Li]CCCC,,test
US20080058423A1,CN(C)C(=O)c1ccc2c(CNC(=O)OC(C)(C)C)cccc2c1>>CNCc1cccc2cc(CN(C)C)ccc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100234351A1,COCCOC(C)CNC(=O)OC(C)(C)C.Cl>>COCCOC(C)CN.Cl,,C1CCOC1,,,,test
US20120238587A1,CC1(C)OB(c2cnc(Cl)c(NS(=O)(=O)c3ccc(F)cc3F)c2)OC1(C)C.Clc1ccc2ncnc(NC3CCOCC3)c2n1>>O=S(=O)(Nc1cc(-c2ccc3ncnc(NC4CCCC4)c3n2)cnc1Cl)c1ccc(F)cc1F,,C1COCCO1,,O=C([O-])O.[Na+],,test
US20030199691A1,CON(C)C(=O)c1cccc(O)c1.OCc1ccc(Cl)cc1>>CON(C)C(=O)c1cccc(OCc2ccc(Cl)cc2)c1,,C1CCOC1,,CCCCP(CCCC)CCCC,,test
US20080242706A1,COC(c1c[nH]c(C)c(OCc2ccccc2)c1=O)C(F)(F)F>>COC(c1c[nH]c(C)c(O)c1=O)C(F)(F)F,[Pd],CO,,,,test
US20140249139A1,CCOC(=O)c1cccc(-c2ncnc3ccc(Br)cc23)c1.COc1ccc(B(O)O)cn1>>CCOC(=O)c1cccc(-c2ncnc3ccc(-c4ccc(OC)nc4)cc23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,ClCCl,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20060122399A1,C1CCNC1.CCc1cc(Br)ccc1CBr>>CCc1cc(Br)ccc1CN1CCCC1,,ClCCl,,,,test
US20090099184A1,O=C(NCc1ccc(Cl)cc1Cl)c1ccnc(F)c1.Oc1ccc(F)cc1>>O=C(NCc1ccc(Cl)cc1Cl)c1ccnc(Oc2ccc(F)cc2)c1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20120282331A1,CC(=O)O[C@@H]1CC[C@]2(C)C3CC[C@]4(C)C(Cl)=C(C=O)CC4C3CC[C@@H]2C1.c1ccc2[nH]cnc2c1>>CC(=O)O[C@@H]1CC[C@]2(C)C3CC[C@]4(C)C(n5cnc6ccccc65)=C(C=O)CC4C3CC[C@@H]2C1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100113458A1,CN(C)CCO.O=[N+]([O-])c1cc(Br)cc([N+](=O)[O-])c1>>CN(C)CCOc1cc(Br)cc([N+](=O)[O-])c1,,CN(C)C=O,O,[K+].[OH-],,test
US04877780,CI.Nc1cc(OCC2CC2)c(C(=O)NC2CN3CCC2CC3)cc1Cl>>CI.Nc1cc(OCC2CC2)c(C(=O)NC2CN3CCC2CC3)cc1Cl,,CC(C)=O,,,,test
US20030158203A1,CC(C)(C)c1cc2nnc(-c3cc(F)ccc3F)n2nc1Cl.Cn1ncnc1CO>>Cn1ncnc1COc1nn2c(-c3cc(F)ccc3F)nnc2cc1C(C)(C)C,,CN(C)C=O,O,[H-].[Na+],,test
US20060173018A1,COCCOC(=O)NC[C@@H]1CCCNC1.Cc1ccc2c(Cl)nc(-c3c(O)cccc3F)nc2c1>>COCCOC(=O)NC[C@@H]1CCCN(c2nc(-c3c(O)cccc3F)nc3cc(C)ccc23)C1,,ClCCl,,CCN(CC)CC,,test
US20160185785A1,CC(C)(C)OC(=O)N1CCC(O)(C(N)CO[Si](C)(C)C(C)(C)C)CC1.Nc1c(C(=O)O)cnn1-c1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCC(O)(C(CO[Si](C)(C)C(C)(C)C)NC(=O)c2cnn(-c3ccc(F)cc3)c2N)CC1,,CCOC(C)=O,ClCCl,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140303206A1,CCOC(=O)C(=O)C(F)(F)F.NC(=O)OCc1ccccc1>>CCOC(=O)[C@@](O)(NC(=O)OCc1ccccc1)C(F)(F)F,,ClCCl,,,,test
US20050272794A1,CC(O)c1ccc(C(=O)NCCC(=O)OC(C)(C)C)cc1.COc1ccc2cc(-c3cc(OS(=O)(=O)C(F)(F)F)[nH]n3)ccc2c1>>COc1ccc2cc(-c3cc(OS(=O)(=O)C(F)(F)F)n(C(C)c4ccc(C(=O)NCCC(=O)OC(C)(C)C)cc4)n3)ccc2c1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040019052A1,N#Cc1cc(-c2cccc(F)c2F)nnc1Cl.NN>>Nc1n[nH]c2nnc(-c3cccc(F)c3F)cc12,,CCO,,O,,test
US20150126498A1,COc1ccc(NS(=O)(=O)c2cnccc2Cl)cc1OC.NCc1c(F)cccc1Cl>>COc1ccc(NS(=O)(=O)c2cnccc2NCc2c(F)cccc2Cl)cc1OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20100324141A1,C[C@@H](N=Cc1ccc(OCc2ccccc2F)cc1)C(N)=O>>C[C@@H](NCc1ccc(OCc2ccccc2F)cc1)C(N)=O,,CO,,[BH4-].[Na+],,test
US20090137561A1,CC1CCCC(C)N1.COC(=O)c1ccc(-c2cc(OC)ccc2F)c(CCl)c1>>COC(=O)c1ccc(-c2cc(OC)ccc2F)c(CN2C(C)CCCC2C)c1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100190754A1,CN(C)N=C(c1ccccc1O)n1ccnc1.ClCOc1ccc(Cl)cc1>>CN(C)N=C(c1ccccc1OCOc1ccc(Cl)cc1)n1ccnc1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120208817A1,COc1cc(C=O)cc(F)c1O.NC(N)=O.O=C(Cc1ccccc1)c1ccccc1>>COc1cc(C2NC(=O)NC(c3ccccc3)=C2c2ccccc2)cc(F)c1O,,CCO,,Cl,,test
US20020115674A1,O=C(Cl)Cl.O=C(NOCc1ccccc1)c1cc(F)c(F)cc1Nc1ccc(O)cc1>>O=c1c2cc(F)c(F)cc2n(-c2ccc(O)cc2)c(=O)n1OCc1ccccc1,,C1COCCO1,,Cc1ccccc1,,test
US20100272680A1,CC1CC(=O)CCN1C(=O)OC(C)(C)C.NCCO>>CC1CC(NCCO)CCN1C(=O)OC(C)(C)C,,CO,O,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20150005289A1,CC(=O)CCl.Nc1ncccc1C1CC1.O=C1CCC(=O)N1Br>>Cc1cn2cc(Br)cc(C3CC3)c2n1,,CC#N,,,,test
US05763458,CC(=O)Nc1c(Cl)cc(C(C)=O)c2c1OCCO2>>CC(=O)c1cc(Cl)c(N)c2c1OCCO2,,CO,,[Na+].[OH-],,test
US07179823B1,BrCc1ccccc1.CCOC(=O)CCc1cn(Cc2ccc(OCc3nc(-c4ccco4)oc3C)cc2)nc1O>>CCOC(=O)CCc1cn(Cc2ccc(OCc3nc(-c4ccco4)oc3C)cc2)nc1OCc1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US20110251186A1,COc1cc(F)c2c(c1)[C@]1(COCC(N)=N1)c1cc(Br)ccc1O2.FC1(F)CCNCC1>>COc1cc(F)c2c(c1)[C@]1(COCC(N)=N1)c1cc(N3CCC(F)(F)CC3)ccc1O2,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20110275611A1,CC1(C)OB(c2ccc(C#N)c(F)c2)OC1(C)C.COc1ccc(-c2c[nH]c(C3CN(c4cc(Cl)nc(N)n4)CCO3)n2)cc1>>COc1ccc(-c2c[nH]c(C3CN(c4cc(-c5ccc(C#N)c(F)c5)nc(N)n4)CCO3)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US04140795,CCOC=NS(C)(=O)=O.CN=CNc1ccc(Cl)cc1C>>Cc1cc(Cl)ccc1N=CN(C)C=NS(C)(=O)=O,,C1COCCO1,,,,test
US04447441,COC(=O)CCCCC(=O)CCl.N=C(NCC(F)(F)F)NC(N)=S>>COC(=O)CCCCc1csc(NC(N)=NCC(F)(F)F)n1,,CCO,,,,test
US20070293516A1,CC(C)n1nc(I)c2c(N)ncnc21.COc1cc(Br)cc(B2OC(C)(C)C(C)(C)O2)c1>>COc1cc(Br)cc(-c2nn(C(C)C)c3ncnc(N)c23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US04386031,COC(=O)CCCCCCCCNc1ccc(OC)cc1.O=C(Cl)c1ccc(Cl)cc1>>COC(=O)CCCCCCCCN(C(=O)c1ccc(Cl)cc1)c1ccc(OC)cc1,,CCOCC,,CCN(CC)CC,,test
US20140194469A1,O=C(O)c1ccnc(-n2ncc(C(=O)O)c2O)c1>>O=C(O)c1ccnc(-n2nccc2O)c1,,Cl,,,,test
US20090130225A1,CSc1nccc(-c2c[nH]cn2)n1.O=C1c2ccccc2C(=O)N1CCCCBr>>CSc1nccc(-c2cn(CCCCN3C(=O)c4ccccc4C3=O)cn2)n1,,CN(C)C=O,,[H-].[Na+],,test
US20130172331A1,CC(F)(F)c1nc(N)c(C(=O)Nc2ccc(F)c([C@@]3(C)N=C(N)OCC3(F)F)n2)nc1Cl>>CC(F)(F)c1cnc(C(=O)Nc2ccc(F)c([C@@]3(C)N=C(N)OCC3(F)F)n2)c(N)n1,[Pd],C1CCOC1,CO,,,test
US20090131455A1,Cc1cc2c(=O)[nH]c(CCl)nc2s1.OCCc1c[nH]nc1C(F)(F)F>>Cc1cc2c(=O)[nH]c(Cn3cc(CCO)c(C(F)(F)F)n3)nc2s1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20060122211A1,CCOC(=O)c1cc2c3cc(N)ccc3n(Cc3cccc(Cl)c3)c2cn1.NO>>Nc1ccc2c(c1)c1cc(C(=O)NO)ncc1n2Cc1cccc(Cl)c1,,CO,O,[Na+].[OH-],,test
US06380387B1,CCI.Cc1c(-c2ccc(C[C@H](NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)c(=O)n(C)c(=O)n1C>>CCOC(=O)[C@H](Cc1ccc(-c2c(C)n(C)c(=O)n(C)c2=O)cc1)NC(=O)c1c(Cl)cccc1Cl,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US04514392,CC1(C)Cc2cccc(O)c2O1.CN(C(=O)Cl)C(=O)CCl>>CN(C(=O)CCl)C(=O)Oc1cccc2c1OC(C)(C)C2,,Cc1ccccc1,,CCN(CC)CC,,test
US04606991,CCCCCCCCCCCCCCCCOc1cc(O)c(NC(C)=O)cc1O>>CCCCCCCCCCCCCCCCOc1cc2oc(C)nc2cc1O,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05215982,Cc1c[nH]c2ccnn12.O=CO>>Cc1cn(C=O)c2ccnn12,,O=CO,,CC(=O)OC(C)=O,,test
US06403584B1,COc1cccc(OC)c1-c1ccc(C(=O)OCc2ccccc2)c(OCc2ccccc2)c1>>COc1cccc(OC)c1-c1ccc(CO)c(OCc2ccccc2)c1,,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US07838521B2,BrC(Br)(Br)Br.COc1ccc(C=O)cc1OC>>COc1ccc(C=C(Br)Br)cc1OC,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20070032518A1,CC(C)(C(N)=S)S(=O)(=O)c1ccccc1.O=C(CBr)c1cc2ccccc2[nH]c1=O>>CC(C)(c1nc(-c2cc3ccccc3[nH]c2=O)cs1)S(=O)(=O)c1ccccc1,,CO,,,,test
US20130267493A1,Brc1ccc(OCC2CNC2)cc1.CC(=O)OC(C)=O>>CC(=O)N1CC(COc2ccc(Br)cc2)C1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20160251306A1,COC(=O)c1ccc(C)c(NC(=O)c2nc(-c3ccccc3)ccc2C)c1C>>Cc1ccc(-c2ccccc2)nc1C(=O)Nc1c(C)ccc(C(=O)O)c1C,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20070197604A1,CC1CCCCN1Cc1coc(-c2ccc(Br)cc2)n1.OB(O)c1cccnc1>>CC1CCCCN1Cc1coc(-c2ccc(-c3cccnc3)cc2)n1,,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20080200473A1,CCI.Cc1ccc(-c2nc3ccc(C)cn3c2CNC(=O)c2ccc(C(F)(F)F)cc2)cc1>>CCN(Cc1c(-c2ccc(C)cc2)nc2ccc(C)cn12)C(=O)c1ccc(C(F)(F)F)cc1,,CN(C)C=O,,[Na+].[OH-],,test
US20060167020A1,CC(C)(C)OC(=O)Nc1ccc(/C=N/Nc2ncnc3c2cnn3-c2ccccn2)cn1.O=C(O)C(F)(F)F>>Nc1ccc(C=NNc2ncnc3c2cnn3-c2ccccn2)cn1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20060276643A1,O=[N+]([O-])c1cc(Cl)cc(-c2cc(Cl)cc([N+](=O)[O-])c2O)c1O>>Nc1cccc(-c2cccc(N)c2O)c1O,[Pd],C1CCOC1,CCN(CC)CC,,,test
US20040038943A1,COc1ccc(C(=O)Cc2cc(F)c(F)cc2[N+](=O)[O-])cc1[N+](=O)[O-]>>COc1ccc(-c2cc3cc(F)c(F)cc3[nH]2)cc1N,[Zn],CC(=O)O,,,,test
US20150210682A1,CCOC(=O)CCCOc1cc2c(cc1OC)-c1cc(=O)c(C(=O)OCC)cn1C(C(C)(C)C)C2>>COc1cc2c(cc1OCCCC(=O)O)CC(C(C)(C)C)n1cc(C(=O)O)c(=O)cc1-2,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20140187533A1,CS(=O)(=O)Cl.NCc1nc2c(C(F)(F)F)cc(C(F)(F)F)cc2[nH]1>>CS(=O)(=O)NCc1nc2cc(C(F)(F)F)cc(C(F)(F)F)c2[nH]1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20080207701A1,N#CCc1ccc(N)cc1.NC(=O)c1ccc(Cl)nc1>>N#CCc1ccc(Nc2ccc(C(N)=O)cn2)cc1,,CCOC(C)=O,CO,,,test
US20030114478A1,CC(C)=O.c1cscn1>>CC(C)(O)c1nccs1,,CCOCC,,[Li]CCCC,,test
US04308391,CCOC(=O)CC(=O)c1ccc(Cl)cc1.O=S(=O)(Cl)Cl>>CCOC(=O)CC(=O)c1ccc(Cl)cc1Cl,,ClC(Cl)Cl,,,,test
US20040058907A1,CCOC(=O)C(F)(F)F.NCC1CNCCO1>>O=C(NCC1CNCCO1)C(F)(F)F,,CO,,,,test
US05763450,O=C(Cl)C1CC1.O=C(Nc1cccc(I)c1)c1ccco1>>O=C(c1ccco1)N(C(=O)C1CC1)c1cccc(I)c1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US04617146,CCOC(=O)C1(C(=O)OCC)CC2=C(C1)C(C)(C)CCC2(C)C>>CC1(C)CCC(C)(C)C2=C1CC(C(=O)O)C2,,CCO,O,[K+].[OH-],,test
US20060052403A1,COC(=O)C(Cc1nc(N)c2nc(O)n(Cc3ccccc3)c2n1)C(=O)OC>>Nc1nc(CCC(=O)O)nc2c1nc(O)n2Cc1ccccc1,,C1COCCO1,,Cl,O=C([O-])O.[Na+],test
US20060172999A1,O=C(OCc1ccccc1)N1CCC(CO)(C(O)CO)CC1>>O=C(OCc1ccccc1)N1CCC2(CC1)COCC2O,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090048252A1,CO.O=C(O)c1ccc2[nH]cnc2c1>>COC(=O)c1ccc2[nH]cnc2c1,,CO,,O=S(Cl)Cl,O=C([O-])O.[Na+],test
US20100137299A1,O=C1C(=O)N(C(c2ccccc2)c2ccccc2)c2ccccc21.Oc1cccc2c1OCCO2>>O=C1N(C(c2ccccc2)c2ccccc2)c2ccccc2C1(O)c1ccc2c(c1O)OCCO2,,C1CCOC1,ClCCCl,CC(C)[Mg]Cl,,test
US20040132727A1,COc1cc2nccc(Oc3ccc(N)c(C)c3)c2cc1OC.O=C(N=C=S)c1ccc([N+](=O)[O-])cc1>>COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)c4ccc([N+](=O)[O-])cc4)c(C)c3)c2cc1OC,,CCO,,Cc1ccccc1,,test
US20040077696A1,NCC1CC1.O=C(O)c1ccc(F)c(NCc2cnc(Nc3ccccn3)s2)c1>>O=C(NCC1CC1)c1ccc(F)c(NCc2cnc(Nc3ccccn3)s2)c1,,CCOC(C)=O,CN(C)C=O,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US20110195948A1,CN1CCN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1.Cl>>CN1CCN(C(=O)Nc2cnn3ccc(N4CCC[C@@H]4c4cc(F)ccc4F)nc23)CC1.Cl,,C1COCCO1,,CO,,test
US04009200,CCCCS.O=C1C=CC(=O)C2C1C1(Cl)C(Cl)=C(Cl)C2(Cl)C1(Cl)Cl>>CCCCSC1CC(=O)C2C(C1=O)C1(Cl)C(Cl)=C(Cl)C2(Cl)C1(Cl)Cl,,c1ccccc1,,,,test
US20060247254A1,Clc1ccc2c(n1)CCC2.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1c(Cl)ccc2c1CCC2,,ClCCl,,,,test
US20050043388A1,COC(=O)CCCCC(=O)Nc1ccc(C(=O)NN=C2C(=O)Nc3ccc(I)cc32)cc1>>O=C(O)CCCCC(=O)Nc1ccc(C(=O)NN=C2C(=O)Nc3ccc(I)cc32)cc1,,C1CCOC1,O,[Na+].[OH-],,test
US20080009530A1,CCCCCS(N)(=O)=O.COCCOc1ccc(CC(C)C(=O)O)c(Oc2ncc(C(F)(F)F)cc2Cl)c1>>CCCCCS(=O)(=O)NC(=O)C(C)Cc1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US20070191376A1,BrBr.c1ccc(COc2cccn3ccnc23)cc1>>Brc1cnc2c(OCc3ccccc3)cccn12,,CCO,,O,[Na+].[OH-],test
US20040063580A1,CCOC(=O)Cl.CSC1=NCCCN1>>CCOC(=O)N1CCCN=C1SC,,C1CCOC1,,CCN(CC)CC,,test
US20130109701A1,COC(=O)c1ccc(O)cc1.Clc1ccc(CBr)cc1Cl>>COC(=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20150119405A1,C=CC(=O)N[C@H]1CNC[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)ccc2n1.CC(=O)Cl>>C=CC(=O)N[C@H]1CN(C(C)=O)C[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)ccc2n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05164407,CCCc1nc2nc(C)n(C)c2n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCc1nc2nc(C)n(C)c2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,CC(=O)O,,,,test
US20020128301A1,C=CCC(C)(C)C(=O)OCc1ccc(OC)cc1.OO>>COc1ccc(COC(=O)C(C)(C)CCCO)cc1,,O,,B1C2CCCC1CCC2,[Na+].[OH-],test
US20070259877A1,COc1ccc(N)cc1N1C[C@H](C)N[C@H](C)C1.O=S(=O)(Cl)c1ccc(Br)cc1>>COc1ccc(NS(=O)(=O)c2ccc(Br)cc2)cc1N1C[C@H](C)N[C@H](C)C1,,ClCCl,,CN1CCOCC1,,test
US20020173469A1,CNCC(C)C.O=C(N=C=S)c1ccccc1>>CC(C)CN(C)C(=S)NC(=O)c1ccccc1,,ClC(Cl)Cl,,,,test
US20070032485A1,CC[C@@H]1C[C@H](N)c2nc(OC)ccc2N1C(=O)OC(C)(C)C.Clc1ncc(Br)cn1>>CC[C@]1(N)C[C@H](c2ncc(Br)cn2)c2nc(OC)ccc2N1C(=O)OC(C)(C)C,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20110105544A1,CCc1ccc(CCC(CCCc2cccc(N)c2)C(=O)OC)cc1.CN(C)c1ccc(C(=O)Cl)cc1>>CCc1ccc(CCC(CCCc2cccc(NC(=O)c3ccc(N(C)C)cc3)c2)C(=O)OC)cc1,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20110034458A1,C=C[Sn](CCCC)(CCCC)CCCC.Clc1ccc2nccnc2n1>>C=Cc1ccc2nccnc2n1,,C1CCOC1,,,,test
US05110956,CCc1cc2c(cc1CC(=O)O)OCO2>>CCc1cc2c(cc1CCO)OCO2,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20100016350A1,CC(C)(C)OC(=O)N[C@@H]1CCN(c2ccc(Br)cn2)C1>>N[C@@H]1CCN(c2ccc(Br)cn2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04563476,Nc1ccccc1CO.O=Cc1cc2c(cc1O)CCCO2>>OCc1ccccc1NCc1cc2c(cc1O)CCCO2,,CO,,[BH4-].[Na+],,test
US20090226398A1,COc1ccc(-c2cnc(C#N)nc2)c(C(F)(F)F)c1.O=CO>>COc1ccc(-c2cnc(CO)nc2)c(C(F)(F)F)c1,[Ni],,,,,test
US20120095020A1,O=C(N[C@H]1c2cc(N3CCNCC3)ccc2OC[C@@H]1O)c1ccc(F)cc1.O=C1COC1>>O=C(N[C@H]1c2cc(N3CCN(C4COC4)CC3)ccc2OC[C@@H]1O)c1ccc(F)cc1,,CC#N,ClCCl,Cl,O=C([O-])O.[Na+],test
US20120046467A1,BrCCOc1ccccc1.OC1CCNCC1>>OC1CCN(CCOc2ccccc2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05990156,CCCN(C)C(=O)[C@@H]1OC(C(=O)OC(c2ccccc2)c2ccccc2)=C[C@H](NC(=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)[C@H]1NC(C)=O.O=C(O)C(F)(F)F>>CCCN(C)C(=O)[C@@H]1OC(C(=O)O)=C[C@H](NC(=N)N)[C@H]1NC(C)=O.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20160214956A1,CCOC(=O)c1cnn(-c2cccc(-c3cc(F)ccc3CCc3ccc(OCCCC(F)(F)F)cc3C)n2)c1C(F)(F)F>>Cc1cc(OCCCC(F)(F)F)ccc1CCc1ccc(F)cc1-c1cccc(-n2ncc(C(=O)O)c2C(F)(F)F)n1,,CCO,O,[Na+].[OH-],,test
US20120053173A1,CC(=O)c1nc(Cl)ccc1O.O=C(CBr)C1CCCCC1>>Cc1c(C(=O)C2CCCCC2)oc2ccc(Cl)nc12,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20060264460A1,N#Cc1cnc2c(C(F)(F)F)cc(N)cc2c1Nc1ccc(F)c(Cl)c1.O=Cc1cccn1S(=O)(=O)c1ccccc1>>N#Cc1cnc2c(C(F)(F)F)cc(NCc3cccn3S(=O)(=O)c3ccccc3)cc2c1Nc1ccc(F)c(Cl)c1,,CCO,,[BH3-]C#N.[Na+],,test
US05006157,COc1c(Cl)cc(C(C)(C)N(CC(C)=O)C(=O)Cc2ccccc2)cc1Cl>>COc1c(Cl)cc(C(C)(C)N2CC(C)=C(c3ccccc3)C2=O)cc1Cl,,CCO,,[K+].[OH-],,test
US20080227770A1,CCOC(=O)CP(=O)(OCC)OCC.COc1cccc([C@H]2O[C@H](CC=O)C(=O)N(CC(C)(C)COC(C)=O)c3ccc(Cl)cc32)c1OC>>CCOC(=O)/C=C/C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(Cl)ccc2N(CC(C)(C)COC(C)=O)C1=O,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20060252811A1,C1=COCC1.ClCCl.O=S(Cl)Cl.OCc1nccn1C1CCCO1.c1c[nH]cn1>>Cl.ClCc1nccn1C1CCCO1.OCc1nccn1C1CCCO1,,ClCCl,,O=C([O-])O.[Na+],,test
US20110086834A1,CC(=O)OC(C)=O.COCCNC(=O)c1cc2cc(Br)ccc2[nH]1>>COCCNC(=O)c1[nH]c2ccc(Br)cc2c1C(C)=O,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US04303583,C=CC(=O)Cl.CCOC(=O)C1Cc2ccccc2N1>>C=CC(=O)N1c2ccccc2CC1C(=O)OCC,,CCOCC,,CCN(CC)CC,,test
US20120184520A1,C1CNCCN1.CN(Cc1cccc(-c2cnc(Cl)nc2)c1)C(=O)CNC(=O)OC(C)(C)C>>CN(Cc1cccc(-c2cnc(N3CCNCC3)nc2)c1)C(=O)CNC(=O)OC(C)(C)C,,CN(C)C=O,,O,,test
US20120289495A1,C1N2CN3CN1CN(C2)C3.Cl.O=C(CBr)c1ccc(F)cc1>>Cl.NCC(=O)c1ccc(F)cc1,,CCO,ClC(Cl)Cl,,,test
US20050187236A1,NC1CCCC1.O=C(Cl)Oc1ccccc1>>O=C(NC1CCCC1)Oc1ccccc1,,C1CCOC1,,c1ccncc1,,test
US20070072944A1,CC(C#N)(CO)NC(=O)c1ccc(OC(F)(F)F)cc1.N#Cc1ccc(C(F)(F)F)c(F)c1>>CC(C#N)(COc1cc(C#N)ccc1C(F)(F)F)NC(=O)c1ccc(OC(F)(F)F)cc1,,C1CCOC1,,[H-].[Na+],,test
US20080221161A1,COc1cc2nc(-c3ccsc3)c(C=O)cc2cc1O.NCCc1ccc(Br)cc1>>COc1cc2nc(-c3ccsc3)c(CNCCc3ccc(Br)cc3)cc2cc1O,,ClCCCl,ClCCl,[BH3-]C#N.[Na+],,test
US20100160303A1,CCOC(=O)Cl.Cc1c(Br)ccc(O)c1C(=O)Nc1ccccc1>>Cc1c(Br)ccc2oc(=O)n(-c3ccccc3)c(=O)c12,,CCOC(C)=O,c1ccncc1,,,test
US04994459,C=CCOc1ccc([N+](=O)[O-])cc1>>C=CCOc1ccc(N)cc1,,Cl,,[Na+].[OH-],,test
US20160229837A1,CN(C(=O)OC(C)(C)C)C1CCNC1.N#Cc1ccc(Cl)nc1>>CN(C(=O)OC(C)(C)C)C1CCN(c2ccc(C#N)cn2)C1,,CCO,,,,test
US20100056511A1,CC(C)(C)C(=O)Cl.O=[N+]([O-])c1ccc(N2CCNCC2)cn1>>CC(C)(C)C(=O)N1CCN(c2ccc([N+](=O)[O-])nc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20090029965A1,CO.Nc1ccc(C(=O)O)c(Cl)c1>>COC(=O)c1ccc(N)cc1Cl,,CO,,CC(=O)Cl,,test
US20040024010A1,CC(=O)Nc1ccc2c(c1)NC(=O)C2.O=Cc1ccc(OCCN2CCOCC2)c(C2CCCCC2)c1>>CC(=O)Nc1ccc2c(c1)NC(=O)C2=Cc1ccc(OCCN2CCOCC2)c(C2CCCCC2)c1,,CCO,CCOC(C)=O,C1CCNCC1,,test
US20110009378A1,CC(C)(C)OC(=O)N1CCc2c(n(CCN)c3ccccc23)C1C1(c2ccc(Cl)cc2)CCC1.CCCS(=O)(=O)Cl>>CCCS(=O)(=O)NCCn1c2c(c3ccccc31)CCNC2C1(c2ccc(Cl)cc2)CCC1,,ClCCl,c1ccncc1,CCN(CC)CC,Cl,test
US04440941,CC(=O)Sc1c(C)cccc1C(=O)N(CC(=O)OC(C)(C)C)C1CCCC1>>CC(=O)Sc1c(C)cccc1C(=O)N(CC(=O)O)C1CCCC1,,CC#N,,C[Si](C)(C)Cl,[I-].[Na+],test
US09085570B2,COC(=O)c1ccc(-c2nc(CS(=O)(=O)c3ccc(F)cc3)c(C)o2)cc1>>Cc1oc(-c2ccc(C(=O)O)cc2)nc1CS(=O)(=O)c1ccc(F)cc1,,C1COCCO1,,[Na+].[OH-],,test
US20090312344A1,C=CC#N.COc1ccc(F)cc1N1CCNCC1>>COc1ccc(F)cc1N1CCN(CCC#N)CC1,,CO,,,,test
US20120115811A1,CCN(C(C)C)C(C)C.ClCCCl.N[C@@H](Cc1ccccc1)C(=O)Nc1cccc(-c2ccncc2)c1.O=Cc1cscn1>>O=C(Nc1cccc(-c2ccncc2)c1)[C@H](Cc1ccccc1)NCCC1CCOCC1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20110144136A1,O=C(Cl)OCc1ccccc1.OCCCC1CCCCN1>>O=C(OCc1ccccc1)N1CCCCC1CCCO,,CC#N,,CCN(CC)CC,,test
US05252601,Nc1ccc(C(=O)O)cc1>>O=C1NC2CCC1CC2,[Rh],O,,,,test
US04241072,CN(C)C(=O)Cl.CN(C)CCNc1nc2ccccc2[nH]1>>CN(C)CCN(C(=O)N(C)C)c1nc2ccccc2[nH]1,,c1ccccc1,,CCN(CC)CC,,test
US20040192723A1,O[C@@H]1Cc2ccccc2O[C@H]1c1ccccc1>>O=C1Cc2ccccc2OC1c1ccccc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US06313137B1,CCOC(=O)C(Cl)C(C)=O.NC(=O)c1cnc(N)c(N)c1>>CCOC(=O)c1c(C)nc2c(N)cc(C(N)=O)cn12,,CCO,,,,test
US20070179173A1,COc1ccc(C2OCCO2)c2c1NC(=O)CC2.ClCc1ccc(Cl)nc1>>COc1ccc(C2OCCO2)c2c1N(Cc1ccc(Cl)nc1)C(=O)CC2,,CN(C)C=O,,[H][H],[H-].[Na+],test
US20060160809A1,C=CCN1CCN(c2ccc(OS(=O)(=O)c3ccc(C(C)C)cc3)cn2)CC1>>CCCN1CCN(c2ccc(OS(=O)(=O)c3ccc(C(C)C)cc3)cn2)CC1,[Pd],CCOC(C)=O,,[H][H],,test
US20160083400A1,CCOC(=O)c1noc(C(C)C)c1[N+](=O)[O-]>>CCOC(=O)c1noc(C(C)C)c1N,[Ni],CO,,,,test
US20050043537A1,COc1ccc([N+](=O)[O-])cc1O.Cc1ccc(S(=O)(=O)OCCCCl)cc1>>COc1ccc([N+](=O)[O-])cc1OCCCCl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090324581A1,O=Cc1cc(C2CC2)c(C(F)(F)F)s1>>OCc1cc(C2CC2)c(C(F)(F)F)s1,,CO,,[BH4-].[Na+],,test
US05364844,CC(C)[C@H]1COC(=O)N1.COc1ccc(CCC(=O)Cl)cc1.[Li]CCCC>>COc1ccc(C(C)CC(=O)N2C(=O)OC[C@@H]2C(C)C)cc1,,C1CCOC1,CCCCCC,[Cl-].[NH4+],,test
US20060051524A1,CC(C)(Br)C(=O)Br.O=[N+]([O-])c1ccc(O)c([N+](=O)[O-])c1>>CC(C)(Br)C(=O)Oc1ccc([N+](=O)[O-])cc1[N+](=O)[O-],,C1CCOC1,,CCN(CC)CC,,test
US20100261771A1,CC(C)(C)OC(=O)NC(CN)c1cccc(C(F)(F)F)c1.COC(=O)Cl>>COC(=O)NCC(NC(=O)OC(C)(C)C)c1cccc(C(F)(F)F)c1,,ClCCl,,CCN(CC)CC,,test
US20040122089A1,C=CCCBr.CCOC(=O)C(C)C>>C=CCCC(C)(C)C(=O)OCC,,C1CCOC1,CN(C)P(=O)(N(C)C)N(C)C,CC(C)NC(C)C,[Li]CCCC,test
US20100137278A1,Clc1nccnc1C1CCCC1.O=C(c1ccc(O)cc1)c1nc2ccccc2[nH]1>>O=C(c1ccc(Oc2nccnc2C2CCCC2)cc1)c1nc2ccccc2[nH]1,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040053908A1,O=[N+]([O-])c1ccc(OCc2ccccc2)cc1F>>Nc1ccc(OCc2ccccc2)cc1F,[Fe],CCO,O,[Cl-].[NH4+],,test
US20020099220A1,BrCC1CO1.N#C[C@@H]1CCCC[C@H]1O>>N#CC1CCCCC1OCC1CO1,,CN(C)C=O,,[H-].[Na+],,test
US20110224202A1,CCc1nnc(-c2ccc(CO)cc2)o1>>CCc1nnc(-c2ccc(C=O)cc2)o1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20110003861A1,COc1ccc(-c2oc3ccc(NC(C)=O)cc3c(=O)c2OCc2ccccc2)cc1.Cl>>COc1ccc(-c2oc3ccc(N)cc3c(=O)c2OCc2ccccc2)cc1.Cl,,CO,ClC(Cl)Cl,[Br-].[K+],,test
US06689909B1,CC(=O)Nc1c(S(=O)(=O)c2ccc(F)cc2)ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c1Cl.NCCO>>CC(=O)Nc1c(S(=O)(=O)c2ccc(NCCO)cc2)ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c1Cl,,CC#N,,,,test
US20100324041A1,CC(C)(C)OC(=O)NCC(=O)N1CCN(c2c(Br)cnc3[nH]cc(NC(=O)c4cccnc4)c23)CC1>>NCC(=O)N1CCN(c2c(Br)cnc3[nH]cc(NC(=O)c4cccnc4)c23)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05635477,CC(C)(C)OC(=O)ON=C(C#N)c1ccccc1.COC(=O)c1ccc2c(c1)C(CN)CCC2>>COC(=O)c1ccc2c(c1)C(CNC(=O)OC(C)(C)C)CCC2,,C1CCOC1,,CCN(CC)CC,CCOC(C)=O,test
US20130123507A1,CC1=NN(c2ccc3c(c2)CCO3)C(=O)C1.Cc1cc(N)c(O)c(-c2cccc(C(=O)O)c2)c1.O=N[O-]>>CC1=NN(c2ccc3c(c2)CCO3)C(=O)C1=NNc1cccc(-c2cc(C)cc(C(=O)O)c2)c1O,,Cl,,O=C([O-])O.[Na+],,test
US20150175594A1,Cc1csc(-c2c(N)sc3c2CCOC3)n1.O=C1OC(=O)C2=C1C1CCC2CC1>>Cc1csc(-c2c(NC(=O)C3=C(C(=O)O)C4CCC3CC4)sc3c2CCOC3)n1,,CCOCC,,,,test
US20150232469A1,CCN(CC)S(F)(F)F.OC(c1ccc(F)cc1F)C1CCN(c2nc3cnccc3nc2NC2CC2)CC1>>Fc1ccc(C(F)C2CCN(c3nc4cnccc4nc3NC3CC3)CC2)c(F)c1,,ClCCl,,,,test
US20130065900A1,COC=Cc1cccc([N+](=O)[O-])c1>>O=CCc1cccc([N+](=O)[O-])c1,,C1CCOC1,CCOC(C)=O,Cl,O,test
US20120184735A1,COc1c(N)cc(N2CCOCC2)cc1C(O)C(F)(F)F.O=C(Cl)OCC(Cl)(Cl)Cl>>COc1c(NC(=O)OCC(Cl)(Cl)Cl)cc(N2CCOCC2)cc1C(O)C(F)(F)F,,C1CCOC1,,CCN(C(C)C)C(C)C,O,test
US20100249119A1,CC(=O)Cl.CC(C)(C)OC(=O)Nc1ccc(F)c(Oc2ccc3nc(N)sc3n2)c1>>CC(=O)Nc1nc2ccc(Oc3cc(NC(=O)OC(C)(C)C)ccc3F)nc2s1,CN(C)c1ccncc1,c1ccncc1,,O,,test
US06136821,Brc1cccc2nonc12.CCOB(OCC)OCC>>OB(O)c1cccc2nonc12,,C1CCOC1,CCCCC,[Li]CCCC,[Cl-].[NH4+],test
US20100216820A1,Cc1ccccc1NC(=O)c1sccc1N.O=C(Cl)CCl>>Cc1ccccc1NC(=O)c1sccc1NC(=O)CCl,,ClCCl,,CCN(CC)CC,O,test
US20090137530A1,CCCCCCCCBr.O=Cc1cc(Br)ccc1O>>CCCCCCCCOc1ccc(Br)cc1C=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04977162,CCOC(=O)c1cc(=O)c2c(O)c(Cl)ccc2o1>>O=C(O)c1cc(=O)c2c(O)c(Cl)ccc2o1,,CC(=O)O,,O,,test
US20090298815A1,CC(C)(C)OC(=O)N1CCC(c2nc(-c3cccc(NS(=O)(=O)c4c(F)cccc4F)c3F)c(-c3ccnc(N)n3)s2)CC1>>Nc1nccc(-c2sc(C3CCNCC3)nc2-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2F)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090286790A1,CCC1CC(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ncc(OCc3ccccc3)cn2)CC(Cc2ccccc2)N1C(=O)OC(C)(C)C>>CCC1CC(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ncc(O)cn2)CC(Cc2ccccc2)N1C(=O)OC(C)(C)C,[Pd],CO,,,,test
US05688774,NCCc1ccccc1.Nc1nc(Cl)nc2c1ncn2[C@@H]1C[C@H](O)[C@@H](O)[C@H]1O>>Nc1nc(NCCc2ccccc2)nc2c1ncn2[C@@H]1C[C@H](O)[C@@H](O)[C@H]1O,,CCO,,,,test
US20090124619A1,CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NCC1CCCN(C(=O)OC(C)(C)C)C1>>CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)NCC1CCCNC1,,C1COCCO1,CO,Cl,,test
US20100286118A1,CC(C)(C)OC(=O)NC1(C(=O)N[C@@H](Cc2ccc(-c3ccc(F)c(F)c3)cc2)C(N)=O)CCOCC1>>CC(C)(C)OC(=O)NC1(C(=O)N[C@H](C#N)Cc2ccc(-c3ccc(F)c(F)c3)cc2)CCOCC1,,ClCCl,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US04868331,COC(=O)COc1cccc2c1CCC(NC(C)=O)C2>>NC1CCc2c(cccc2OCC(=O)O)C1,,Cl,,,,test
US20070135477A1,COc1cc([N+](=O)[O-])c(NC(C)=O)cc1OCN1CCC(C)CC1>>COc1cc([N+](=O)[O-])c(N)cc1OCN1CCC(C)CC1,,CO,,C[O-].[Na+],,test
US20110201605A1,CO.Fc1ccc(-c2cccn3nc(NC4CCN(c5ccnc(Cl)n5)CC4)nc23)cc1F>>COc1nccc(N2CCC(Nc3nc4c(-c5ccc(F)c(F)c5)cccn4n3)CC2)n1,,CO,,C[O-].[Na+],,test
US20030153570A1,CO.O=C(O)c1cc(Cl)ccc1F>>COC(=O)c1cc(Cl)ccc1F,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20120015942A1,COC(=O)C1CCc2cc(O)ccc2C1.O=[N+]([O-])c1ccnc(Cl)c1>>COC(=O)C1CCc2cc(Oc3ccnc(Cl)c3)ccc2C1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100216814A1,BrC(Br)(Br)Br.O=Cc1ccc(F)cc1>>Fc1ccc(C=C(Br)Br)cc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US05998433,CN(C)Cc1cc2c(o1)CCN(C(=O)c1ccc(/C=C\c3ccc(Cl)cc3)cc1)C2.Cl>>CN(C)Cc1cc2c(o1)CCN(C(=O)c1ccc(/C=C\c3ccc(Cl)cc3)cc1)C2.Cl,,CCOC(C)=O,CO,,,test
US20090088406A1,CC(C)(C)OC(=O)N1CC[C@@H](OS(C)(=O)=O)C1.Clc1ccc(Nc2ccccc2)cc1Cl>>CC(C)(C)OC(=O)N1CC[C@H](N(c2ccccc2)c2ccc(Cl)c(Cl)c2)C1,,CCOC(C)=O,,CS(C)=O,[H-].[Na+],test
US04785017,CC1(C(=O)O)CCc2cc(O)ccc2O1.CCCc1c(OCCCBr)ccc(C(C)=O)c1O>>CCCc1c(OCCCOc2ccc3c(c2)CCC(C)(C(=O)O)O3)ccc(C(C)=O)c1O,,CN(C)C=O,,[H-].[Na+],,test
US06043248,CC(C)(C)[Si](C)(C)Cl.Nc1nc(SCc2ccc3ccccc3c2)nc(O)c1CCO>>CC(C)(C)[Si](C)(C)OCCc1c(N)nc(SCc2ccc3ccccc3c2)nc1O,,c1ccncc1,,ClCCl,,test
US03939266,O=CC1=CS[C@@H]2C(NC(=O)Cc3cccs3)C(=O)N2C1C(=O)O.[N-]=[N+]=C(c1ccccc1)c1ccccc1>>O=CC1=CS[C@@H]2C(NC(=O)Cc3cccs3)C(=O)N2C1C(=O)OC(c1ccccc1)c1ccccc1,,C1CCOC1,,,,test
US20140005164A1,CC(=O)N1CCNCC1.Cn1c(=O)n(C[C@@H]2CC[C@@H](C(=O)O)CC2)c2cc(O)ccc21>>CC(=O)N1CCN(C(=O)[C@@H]2CC[C@@H](Cn3c(=O)n(C)c4ccc(O)cc43)CC2)CC1,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20110217311A1,CO[C@H]1CCCC[C@@H]1Oc1cc(F)ccc1Nc1ncnc2sc(C(=O)O)c(C)c12.O=C1CCC(=O)N1O>>CO[C@H]1CCCC[C@@H]1Oc1cc(F)ccc1Nc1ncnc2sc(C(=O)ON3C(=O)CCC3=O)c(C)c12,,CCOC(C)=O,CN(C)C=O,ClCCCl,,test
US20130023539A1,COC(=O)[C@@H]1CC[C@H](c2ccccc2Cl)N1C(=O)c1ccc(-c2ccccc2C#N)cc1.NO>>COC(=O)[C@@H]1CC[C@H](c2ccccc2Cl)N1C(=O)c1ccccc1-c1ccccc1/C(N)=N\O,,CCO,,CCN(CC)CC,Cl,test
US20110166169A1,CC(N)=O.COC(=O)c1cccc2c1c1ccccc1n2-c1ccc(C#N)c(Br)c1>>COC(=O)c1cccc2c1c1ccccc1n2-c1ccc(C#N)c(NC(C)=O)c1,I[Cu]I,C1COCCO1,CCOC(C)=O,CN[C@@H]1CCCC[C@H]1NC,O=C([O-])[O-].[K+].[K+],test
US04404224,CC(C)NCC(Cl)c1ccc(O)c(NS(C)(=O)=O)c1.[O-]c1ccccc1>>CC(C)NC(Cc1ccc(O)c(NS(C)(=O)=O)c1)Oc1ccccc1,,C1CCOC1,,Cl,,test
US20110306610A1,CCCCOc1nc(N)c2[nH]c(=O)n(CCCCN(CCN3CCCC3)S(=O)(=O)c3cccc(CC(=O)OC)c3)c2n1>>CCCCOc1nc(N)c2[nH]c(=O)n(CCCCN(CCN3CCCC3)S(=O)(=O)c3cccc(CC(=O)O)c3)c2n1,,O,,C1CCOC1,[Li+].[OH-],test
US06121285,CCOC(=O)C1(C2=CC(=O)N([C@@H](C)c3ccccc3)C2)CCC1>>CCOC(=O)C1(C2CC(=O)N([C@@H](C)c3ccccc3)C2)CCC1,O=[Pt],CCO,,[H][H],,test
US20040242572A1,COC(=O)c1ccc(OCCCC(F)(F)F)cc1>>O=C(O)c1ccc(OCCCC(F)(F)F)cc1,,C1CCOC1,,[Na+].[OH-],,test
US05457124,O=C1CCCC(=O)C1=CC=Cc1ccccc1>>O=C1CCCC(=O)C1CCCc1ccccc1,[Pd],CCOC(C)=O,,[H][H],,test
US20020156081A1,Brc1ccc(N=Cc2ccccc2)cc1.[Li]C>>CC(Nc1ccc(Br)cc1)c1ccccc1,,CCOCC,Cc1ccccc1,,,test
US05250517,BrCc1ccccc1.CCOC(=O)CC#N>>CCOC(=O)C(C#N)Cc1ccccc1,,CCO,,C,C[O-].[Na+],test
US20070123512A1,CC(=O)Nc1ccc(O)cc1.Cc1cc(NC(=O)C2(C)CO2)ccc1[N+](=O)[O-]>>CC(=O)Nc1ccc(OCC(C)(O)C(=O)Nc2ccc([N+](=O)[O-])c(C)c2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20100216788A1,CC(C)(C)NC(=O)c1cccc(Cn2ncc3cc([N+](=O)[O-])ccc32)c1>>CC(C)(C)NC(=O)c1cccc(Cn2ncc3cc(N)ccc32)c1,[Pt],CCOC(C)=O,,,,test
US06534546B1,CC(C)(C)OC(=O)NC(C)(C)c1cccc(N)c1.CN(N=O)C(=N)N[N+](=O)[O-]>>CC(C)(C)OC(=O)NC(C)(C)c1cccc(NC(N)=N[N+](=O)[O-])c1,,CC(=O)O,,CC#N,CCN(CC)CC,test
US20100048568A1,Nn1ccc2cc(F)ccc21.O=C(Cl)c1cnc(-c2cccc(F)c2)nc1>>O=C(Nn1ccc2cc(F)ccc21)c1cnc(-c2cccc(F)c2)nc1,,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20090156594A1,BrBr.O=CCc1ccccc1>>O=CC(Br)c1ccccc1,,ClCCl,,O=C([O-])O.[Na+],,test
US20040132748A1,CCCCOc1nc(N)c2[nH]cnc2n1.ClCc1ccc(Cl)nc1>>CCCCOc1nc(N)c2ncn(Cc3ccc(Cl)nc3)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100249123A1,CC(C)(C#N)c1ccc([N+](=O)[O-])cc1Br>>CC(C)(C#N)c1ccc(N)cc1Br,O=[Pt]=O,CO,,,,test
US05556864,CC(C)(C)OC(=O)N1C[C@H](O)CC1COc1ccccc1CCCCc1ccccc1.Cl>>Cl.O[C@H]1CNC(COc2ccccc2CCCCc2ccccc2)C1,,C1COCCO1,,,,test
US20150197527A1,O=C(O)CCl.O=c1c2[nH]c3ccccc3c2[nH]c(=S)n1-c1ccccc1>>O=C(O)CSc1nc2c([nH]c3ccccc32)c(=O)n1-c1ccccc1,,CCO,,[K+].[OH-],,test
US20010056179A1,NC1(C(=O)O)CCC(c2ccccc2)(c2ccccc2)CC1.O=C(OCC1c2ccccc2-c2ccccc21)ON1C(=O)CCC1=O>>NC1(C(=O)O)CCC(c2ccccc2)(c2ccccc2)CC1C(=O)OCC1c2ccccc2-c2ccccc21,,CC#N,O,CCN(CC)CC,,test
US20110112080A1,CC(C)(C)OC(=O)N1[C@@H](/C=C/c2ccc([N+](=O)[O-])cc2)COC1(C)C>>CC(C)(C)OC(=O)N1[C@@H](CCc2ccc(N)cc2)COC1(C)C,[Pd],CO,,O=C[O-].[NH4+],,test
US20050101590A1,CCCCn1c2c(cc(O)c1=O)CCCC2.Clc1nc2ccccc2o1>>CCCCn1c2c(cc(Oc3nc4ccccc4o3)c1=O)CCCC2,,CN(C)C=O,,Cl,[H-].[Na+],test
US20130072470A1,Cc1ccc(S(=O)(=O)n2ccc3c2ncc2ncc([C@H]4CN(C(=O)CC5CC5)C[C@H]4C)n23)cc1>>C[C@@H]1CN(C(=O)CC2CC2)C[C@@H]1c1cnc2cnc3[nH]ccc3n12,,C1COCCO1,,[Na+].[OH-],,test
US20140231754A1,Brc1ccc2c(c1)[nH]c1cc(Br)ccc12.Ic1ccccc1>>Brc1ccc2c3ccc(Br)cc3n(-c3ccccc3)c2c1,[Cu],CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05047554,O=C(O)c1sccc1Cl.O=S(Cl)Cl>>O=C(Cl)c1sccc1Cl,,Cc1ccccc1,,,,test
US06420386B1,CCOP(=O)(OCC)c1cc2cc(-n3cccc3)c(Cl)cc2[nH]c1=O>>O=c1[nH]c2cc(Cl)c(-n3cccc3)cc2cc1P(=O)(O)O,,ClCCl,,C[Si](C)(C)Br,,test
US05849757,CCOC(=O)C(C)(C(=O)OCC)c1c(F)c(F)c(C(=O)OC)c(C(=O)OC)c1F>>CC(C(=O)O)c1c(F)c(F)c(C(=O)O)c(C(=O)O)c1F,,CC(=O)O,,Cl,,test
US20140288109A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)CC(=O)NCC1(C(=O)OC)CCN(Cc2ccccc2)C1>>CCOC(=O)CC(=O)NCC1(C(=O)OC)CCN(C(=O)OC(C)(C)C)C1,[Pd],CCOC(C)=O,,,,test
US20160176822A1,CCI.CCOC(=O)C1c2ccc(O)cc2CCN1C(=O)OC(C)(C)C>>CCOC(=O)C1c2ccc(OCC)cc2CCN1C(=O)OC(C)(C)C,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US06353127B1,N#CC(O)c1ccccc1.O=C(Cl)Cl>>N#CC(Cl)c1ccccc1,,Cc1ccccc1,,N#N,,test
US20060035956A1,CN(CC#Cc1ccc(OC(F)(F)F)cc1)C(=O)OC(C)(C)C>>CNCC#Cc1ccc(OC(F)(F)F)cc1,,ClCCl,,C1COCCO1,Cl,test
US06960575B2,NC(=O)CS.O=C(CBr)c1ccccc1>>O=C1CSC=C(c2ccccc2)N1,,CCO,,CCN(CC)CC,,test
US20100076026A1,COC(=O)c1ccc(N=C=O)c(Cl)c1.Clc1ccc(-n2nc3ccccc3c2NCc2ccccc2)cc1>>COC(=O)c1ccc(NC(=O)N(Cc2ccccc2)c2c3ccccc3nn2-c2ccc(Cl)cc2)c(Cl)c1,,Cc1ccccc1,,,,test
US20120214803A1,O=[N+]([O-])c1c(C(O)c2ccc(F)cn2)ccc2cccnc12>>O=C(c1ccc(F)cn1)c1ccc2cccnc2c1[N+](=O)[O-],,ClCCl,,O=[Cr](=O)([O-])O[Cr](=O)(=O)[O-].c1cc[nH+]cc1.c1cc[nH+]cc1,,test
US20140093453A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCN(CCN)CCOc1cccnc1F>>CCN(CCNC(=O)OC(C)(C)C)CCOc1cccnc1F,,ClCCl,,CCN(CC)CC,Cl,test
US05661169,CCOc1ccc2c(c1)n(C1CCCCC1)c(=O)n2Cc1ccc(C(=O)NC(C)(C)C)cc1OC.CN(C)CC(C)(C)N>>CCOc1ccc2c(c1)n(C1CCCCC1)c(=O)n2Cc1ccc(C(=O)NC(C)(C)CN(C)C)cc1OC,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20160083380A1,CCOC(=O)COc1ccc(C(C)=NOCc2ccc(C(F)(F)F)cc2)cc1.NN>>CC(=NOCc1ccc(C(F)(F)F)cc1)c1ccc(OCC(=O)NN)cc1,,CCO,,O,,test
US20140228376A1,CC(O)(C(=O)NNC(=O)c1ncc(C(F)(F)F)cc1N)C(F)(F)F.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(O)(c1nnc(-c2ncc(C(F)(F)F)cc2N)s1)C(F)(F)F,,Cc1ccccc1,O,,,test
US20120004262A1,N[C@@H]1C[C@H]1c1ccccc1.O=Cc1ccc(F)cc1>>Fc1ccc(CN[C@@H]2C[C@H]2c2ccccc2)cc1,,ClCCl,O,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20150065705A1,CC1CC(O)(c2ccc(F)cc2)CCN1C(=O)OC(C)(C)C.NS(F)(F)F>>CC1CC(F)(c2ccc(F)cc2)CCN1C(=O)OC(C)(C)C,,ClC(Cl)Cl,,ClCCl,O=C([O-])[O-].[Na+].[Na+],test
US05276154,CCOC(=O)/C=C/C(=C(c1ccc(F)cc1)c1ccc(F)cc1)C(C)C>>CC(C)C(/C=C/C(=O)O)=C(c1ccc(F)cc1)c1ccc(F)cc1,,Cc1ccccc1,,Cl,[Na+].[OH-],test
US20140371212A1,NC(N)=S.O=C([O-])NC(=O)c1ccccc1>>NC(=O)NC(=O)c1ccccc1,,CCN(CC)CC,,,,test
US20100009978A1,COc1cc(Nc2nc3cccc(-c4ccc(C#N)cc4)c3o2)cc(OC)c1OC>>COc1cc(Nc2nc3cccc(-c4ccc(CN)cc4)c3o2)cc(OC)c1OC,[Ni],C1CCOC1,CO,,,test
US20150210688A1,Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1-c1[nH]c(CCO)nc1C.O=S(Cl)Cl>>Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1-c1[nH]c(CCCl)nc1C,,ClCCl,,,,test
US20100160303A1,CC(C)(C)OC(=O)n1ccc2ccc(-c3ccc(F)cc3)cc21.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)n1cc(Br)c2ccc(-c3ccc(F)cc3)cc21,,C1CCOC1,CCOCC,,,test
US05585394,COc1cc(N)ccc1S(=O)(=O)n1c(=O)n(C2CCCCC2)c2cc(Cl)ccc21.O=C(Cl)Oc1ccccc1>>COc1cc(NC(=O)Oc2ccccc2)ccc1S(=O)(=O)n1c(=O)n(C2CCCCC2)c2cc(Cl)ccc21,,C1CCOC1,O,[Na+].[OH-],,test
US04810713,ClCCCOc1ccc(Cl)cc1.OC(c1ccc(F)cc1)(c1ccc(F)cc1)C1CCNCC1>>OC(c1ccc(F)cc1)(c1ccc(F)cc1)C1CCN(CCCOc2ccc(Cl)cc2)CC1,,CCCCO,,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US20100069337A1,CCCCO.O=P(Cl)(Oc1ccc(Cl)cc1Cl)Oc1ccc(Cl)cc1Cl>>CCCCOP(=O)(Oc1ccc(Cl)cc1Cl)Oc1ccc(Cl)cc1Cl,,ClCCl,,c1ccncc1,,test
US06316490B1,CN1CCCC1CCCl.Sc1ccccc1>>CN1CCCC1CCSc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090264431A1,CC(C)(C)OC(=O)N1C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@@H]1CO.Oc1ccc(F)cc1>>CC(C)(C)OC(=O)N1C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@@H]1COc1ccc(F)cc1,,C1CCOC1,CCOC(C)=O,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150239900A1,O=S(Cl)Cl.O=c1cn[nH]c2cc(Br)c(Cl)cc12>>Clc1cc2c(Cl)cnnc2cc1Br,CN(C)C=O,,,,,test
US04742060,NCCS.O=Cc1ccc(Cl)nc1>>Clc1ccc(C2NCCS2)cn1,,c1ccccc1,,,,test
US20040157849A1,Cc1ccc(N)c2cn[nH]c12.O=C(Cl)C(Cl)(Cl)Cl>>Cc1ccc(NC(=O)C(Cl)(Cl)Cl)c2cn[nH]c12,,ClCCl,,CCN(CC)CC,,test
US20110046093A1,CN1CCN(N)CC1.COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(C)(C)C(=O)N2C>>COc1cc(C(=O)NN2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(C)(C)C(=O)N2C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20030119870A1,CCOC(=O)C(=O)Cl.Cc1cc(N)cc(N2CCc3ccccc3C2)n1>>CCOC(=O)C(=O)Nc1cc(C)nc(N2CCc3ccccc3C2)c1,,C1CCOC1,c1ccncc1,,,test
US04113731,CCOC(=O)Cl.Cn1c(N)c(-c2ccccc2)c2ccccc21>>Cn1c2ccccc2c2c3ccccc3c(=O)[nH]c21,,c1ccncc1,,Cl,,test
US05135955,CCCCOc1ccc(CCC(C)N(C)C)cc1.CI>>CCCCOc1ccc(CCC(C)[N+](C)(C)C)cc1.[I-],,CCOCC,,,,test
US20160046637A1,CC(=O)OC1CCN(c2nc(C(C)(C)C)nc3[nH]ccc23)C1.Clc1ccccc1CBr>>CC(C)(C)c1nc(N2CCC(O)C2)c2ccn(Cc3ccccc3Cl)c2n1,,CN(C)C=O,,[H-].[Na+],,test
US20070142428A1,COC(=O)C(=Cc1cccc(F)c1C1OCCCO1)NC(C)=O>>COC(=O)c1cc2cccc(F)c2cn1,,CC(C)=O,O,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20090312382A1,CC(C)N1C(=O)N(S(=O)(=O)c2ccccc2)CC1c1cccc(-c2cccc(S(C)(=O)=O)c2)c1>>CC(C)N1C(=O)NCC1c1cccc(-c2cccc(S(C)(=O)=O)c2)c1,,CO,,[Mg],,test
US20140142102A1,COc1cc(-c2ccccc2)cc(N)c1C#N.[OH-]>>COc1cc(-c2ccccc2)cc(N)c1C(N)=O,,CCO,,Cl,,test
US20160096839A1,CC(C)OB1OC(C)(C)C(C)(C)O1.CC(F)(F)c1ccc(Cl)c(F)c1>>CC(F)(F)c1ccc(Cl)c(F)c1B1OC(C)(C)C(C)(C)O1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US06084130,CCCN(CCC)C1Cc2cc(C(=O)[O-])c(C(=O)[O-])cc2C1.NCc1ccc(F)cc1>>CCCN(CCC)C1Cc2cc3c(cc2C1)C(=O)N(Cc1ccc(F)cc1)C3=O,,CC(=O)O,,,,test
US20110118245A1,CCOC(=O)Cn1nc(C(C)(C)C)cc1NC(=O)Nc1cccc(Oc2ncnc3cc(OCCOC)c(OC)cc23)c1.Cl>>CCOC(=O)Cn1nc(C(C)(C)C)cc1NC(=O)Nc1cccc(Oc2ncnc3cc(OCCOC)c(OC)cc23)c1.Cl,,CO,ClCCl,CCOCC,,test
US20110245274A1,NO.O=Cc1ccc(F)c2ccccc12>>ON=Cc1ccc(F)c2ccccc12,,C1CCOC1,O,Cl,CC(=O)[O-].[Na+],test
US05455260,ClCCl.c1ccc(CCCCOCC(COCc2ccc(-c3nc4ccccc4o3)cc2)NC(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>Cl.NC(COCCCCc1ccccc1)COCc1ccc(-c2nc3ccccc3o2)cc1,,CO,,,,test
US20050197350A1,Cc1cnc(N[C@@H]2CC[C@H](N)CC2)nc1N(C)C.O=C(Br)CBr>>Cc1cnc(N[C@@H]2CC[C@H](NC(=O)CBr)CC2)nc1N(C)C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20130172351A1,N#Cc1cccc(C2=NN(C(=O)c3cccc(F)c3)CC2)c1>>Cc1cccc(C2=NN(C(=O)c3cccc(F)c3)CC2)c1,[Pd],CCO,,CCOC(C)=O,,test
US05700809,C(=Cc1ccco1)c1ccncc1>>c1coc(CCc2ccncc2)c1,[Pd],CO,,O=C[O-].[NH4+],,test
US20100099695A1,COC(=O)c1cc2cccnc2nc1O>>O=C(O)c1cc2cccnc2nc1O,,C1CCOC1,O,[Li+].[OH-],,test
US20110218177A1,COc1cc(CCO)ccc1OC(C)=O.Cc1ccc(S(=O)(=O)Cl)cc1>>COc1cc(CCOS(=O)(=O)c2ccc(C)cc2)ccc1OC(C)=O,,O,c1ccncc1,,,test
US20100087419A1,COC(=O)c1nc2n(c(=O)c1OS(C)(=O)=O)[C@H](C)CCC[C@H]2N(C)C(=O)OC(C)(C)C>>CN[C@@H]1CCC[C@@H](C)n2c1nc(C(=O)OC)c(OS(C)(=O)=O)c2=O,,C1COCCO1,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US04794183,CCCCCCCCCCCCCCCCBr.OCC1=CCCCO1>>CCCCCCCCCCCCCCCCOCC1=CCCCO1,,Cc1ccccc1,,[K+].[OH-],,test
US05739345,Cn1c(COc2ccc(CC3SC(=O)N(C(c4ccccc4)(c4ccccc4)c4ccccc4)C3=O)cc2)nc2cc(Br)cnc21>>Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2cc(Br)cnc21,,O,,CC(=O)O,,test
US04332808,CCCN1CCCC(O)(c2cccc3c2ccn3C)C1>>CCCN1CCC=C(c2cccc3c2ccn3C)C1,,Cl,,[Na+].[OH-],,test
US20100204235A1,CNC(=O)c1cccc(-c2cnn3ccnc3c2)c1.O=C1CCC(=O)N1Br>>CNC(=O)c1cccc(-c2cnn3c(Br)cnc3c2)c1,,CCOC(C)=O,CN(C)C=O,,,test
US20140322195A1,Nc1cc2ccnc(N3C(=O)c4ccccc4C3=O)c2cn1.O=CO>>O=CNc1cc2ccnc(N3C(=O)c4ccccc4C3=O)c2cn1,,ClCCl,,CC(=O)OC(C)=O,,test
US06432881B1,COC(=O)c1ccc(S(C)(=O)=O)c(CBr)c1Cl.Cn1nccc1O>>COC(=O)c1ccc(S(C)(=O)=O)c(COc2ccnn2C)c1Cl,,CCOC(C)=O,,C1CCOC1,O=C([O-])[O-].[K+].[K+],test
US20160002188A1,Cc1nc2ccccc2n1-c1ccc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cc1.Cl>>Cc1nc2ccccc2n1-c1ccc(C(=O)N2CCNCC2)cc1.Cl,,C1CCOC1,,ClCCl,,test
US20100204206A1,BrCC1CC1.OC1(c2nc(-c3ccccc3)cs2)CCC2(CC1)OCCO2>>c1ccc(-c2csc(C3(OCC4CC4)CCC4(CC3)OCCO4)n2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04204071,BrP(Br)Br.OCC(F)=Cc1ccccc1>>FC(=Cc1ccccc1)CBr,,CCOCC,,,,test
US20010025045A1,CC(=O)OC(C)=O.COc1cc(OC)c(C(=O)Nc2cccc3c2CCNC3)cc1Br>>COc1cc(OC)c(C(=O)Nc2cccc3c2CCN(C(C)=O)C3)cc1Br,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20060247305A1,CC(=O)Cl.COc1cc(O)c(CC(C)C)c(OC)c1OC>>COc1c(CC(C)C)c(O)c(C(C)=O)c(OC)c1OC,,CC(Cl)Cl,,CCOCC,FB(F)F,test
US20110275611A1,FC(F)(F)C1CCCN1.Nc1nc(Cl)cc(Cl)n1>>Nc1nc(Cl)cc(N2CCCC2C(F)(F)F)n1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20100267723A1,Cc1ncc(-c2nc(Nc3cc(F)c(CN4[C@@H](C)COC[C@@H]4C)cc3F)ncc2F)n1C1CCOCC1.Cl>>Cc1ncc(-c2nc(Nc3cc(F)c(CN4[C@@H](C)COC[C@@H]4C)cc3F)ncc2F)n1C1CCOCC1.Cl,,ClCCl,,,,test
US20150087639A1,CCOC(=O)C(F)(F)Br.Oc1cccc(F)c1>>CCOC(=O)C(F)(F)Oc1cccc(F)c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04831041,COCOc1cccc(COc2cccnc2N)c1>>Nc1ncccc1OCc1cccc(O)c1,,O=S(=O)(O)O,,,,test
US04877446,CC(=O)C(C)(C)Cc1ccc(SC(F)(F)F)cc1.CCOC=O>>CC(C)(Cc1ccc(SC(F)(F)F)cc1)C(=O)C=CO,,CCOCC,,C[O-].[Na+],,test
US20070179173A1,CCOC(=O)c1ccccc1B1OCCCCCC(C)(C)O1.N#Cc1ccc(N)c(I)c1>>N#Cc1ccc2[nH]c(=O)c3ccccc3c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20110213143A1,CCCc1ccc2c(c1)CCc1c(C[C@H](CCCNC(=O)OC(C)(C)C)C(=O)O[C@H](c3ccccc3)[C@H](C)N3CCCC3)ncn1-2>>CCCc1ccc2c(c1)CCc1c(C[C@H](CCCNC(=O)OC(C)(C)C)C(=O)O)ncn1-2,[Pd],CO,,,,test
US20050096380A1,CCOc1c(C(CC)=C(F)C=CC(C)=CC(=O)[O-])cc2c(c1Br)C(C)(C)CC=C2C(C)CC>>CCOc1c(C(CC)=C(F)C=CC(C)=CC(=O)O)cc2c(c1Br)C(C)(C)CC=C2C(C)CC,,CCO,,C1CCOC1,[Na+].[OH-],test
US06294555B1,CC(C)(C)OC(=O)NC1CCN(CC2CCNCC2)CC1.C[Si](C)(C)N=C=O>>CC(C)(C)OC(=O)NC1CCN(CC2CCN(C(N)=O)CC2)CC1,,ClCCl,,,,test
US04760140,CC(=O)OCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)[C@@H](Nc3ncc(C(=O)c4ccccc4)s3)[C@H]2SC1>>CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](Nc3ncc(C(=O)c4ccccc4)s3)[C@H]2SC1,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US20080312207A1,CC(C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(C(=O)Nc2nc(CCl)cs2)c1.CNC>>CC(C)Oc1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(C(=O)Nc2nc(CN(C)C)cs2)c1,,C1CCOC1,,,,test
US20080146637A1,CC(=O)c1ccccc1-c1ccc2[nH]c(COc3ccc(C(F)(F)F)cc3)nc2c1.CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F>>C=C(O[Si](C)(C)C(C)(C)C)c1ccccc1-c1ccc2[nH]c(COc3ccc(C(F)(F)F)cc3)nc2c1,,ClCCl,,CCN(CC)CC,,test
US20110172202A1,CC(C)CBr.N#Cc1cc(-c2nc(-c3cccc4c3CCC4NCCO)no2)ccc1O>>CC(C)COc1ccc(-c2nc(-c3cccc4c3CCC4NCCO)no2)cc1C#N,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20070191372A1,Cc1ccc2c(c1)nc(NCCCN(C)CCCNC(=O)OC(C)(C)C)n[n+]2[O-]>>Cc1ccc2c(c1)nc(NCCCN(C)CCCN)n[n+]2[O-],,Cl,,,,test
US07037929B1,C1COCCN1.CC(C)c1cnc(NC(=O)Cc2cccc(OCCCCl)c2)s1>>CC(C)c1cnc(NC(=O)Cc2cccc(OCCCN3CCOCC3)c2)s1,,CN(C)C=O,,[I-].[K+],,test
US05767131,N#CCCN1CCC(c2ccccc2)(c2ccccc2)CC1>>NCCCN1CCC(c2ccccc2)(c2ccccc2)CC1,,C1CCOC1,,Cl,[Na+].[OH-],test
US08647827B2,CI.Cc1cc(N(C)C)ccc1-c1ccncc1>>Cc1cc(N(C)C)ccc1-c1cc[n+](C)cc1.[I-],,CC#N,,,,test
US20110245310A1,CC(C)c1nc2c(n1Cc1ccc(Cl)cc1)C(O)CC2.CCOC(=O)CBr.CN(C)C=O>>CC(C)c1nc2c(n1Cc1ccc(Cl)cc1)C(OCC(=O)O)CC2.N,,CN(C)C=O,,[H-].[Na+],,test
US20090105242A1,O=C1CCCCC1.O=[N+]([O-])c1ccc(N2CCNCC2)cc1>>O=[N+]([O-])c1ccc(N2CCN(C3CCCCC3)CC2)cc1,,ClCCl,,,,test
US05556977,COC(=O)C(C)(C)Oc1ccc(C(=O)CBr)cc1.c1cc(N2CCNCC2)ccn1>>COC(=O)C(C)(C)Oc1ccc(C(=O)CN2CCN(c3ccncc3)CC2)cc1,,CC#N,,CCN(CC)CC,CCOCC,test
US20070232627A1,CC(C)(C)OC(=O)n1ccc2cc(Oc3ccc(C(=O)Nc4ccc(Br)cc4)cc3[N+](=O)[O-])ccc21>>CC(C)(C)OC(=O)n1ccc2cc(Oc3ccc(C(=O)Nc4ccc(Br)cc4)cc3N)ccc21,[Fe],CCO,O,[Cl-].[NH4+],,test
US20090118276A1,N#Cc1cnc2cc(-c3ccncc3)sc2c1-c1cccc(N)c1.O=C=Nc1cccc(C(F)(F)F)c1>>N#Cc1cnc2cc(-c3ccncc3)sc2c1-c1cccc(NC(=O)Nc2cccc(C(F)(F)F)c2)c1,,C1CCOC1,,,,test
US20160264552A1,C=CC(=O)Nc1ccc(CNC(=O)C2CC(Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)CN(C(=O)OC(C)(C)C)C2)cc1>>C=CC(=O)Nc1ccc(CNC(=O)C2CNCC(Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)C2)cc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20090029955A1,CCOC(=O)N1CCN(CCNc2ncnc3c2sc2nc(N4CCCC4)c4c(c23)CC(C)(C)CC4)CC1>>CC1(C)CCc2c(N3CCCC3)nc3sc4c(NCCN5CCNCC5)ncnc4c3c2C1,,CC(C)O,,[K+].[OH-],,test
US20060004203A1,COC(=O)[C@H](N)Cc1c[nH]c2ccccc12.O=Cc1ccc2c(c1)OCO2>>COC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H](c2ccc3c(c2)OCO3)N1,,CC(C)O,,Cl,,test
US20110076292A1,COC(=O)[C@H](CO[Si](C)(C)C(C)(C)C)Oc1ccc2c(c1)OCCn1cc(-c3ncnn3CC(F)(F)F)nc1-2.N>>CC(C)(C)[Si](C)(C)OC[C@H](Oc1ccc2c(c1)OCCn1cc(-c3ncnn3CC(F)(F)F)nc1-2)C(N)=O,,CO,,,,test
US20090075938A1,CCCC(=O)Nc1cc([N+](=O)[O-])ccc1C#Cc1ccccc1>>O=[N+]([O-])c1ccc2cc(-c3ccccc3)[nH]c2c1,,CN1CCCC1=O,,O,CC(C)(C)[O-].[K+],test
US04504486,CCCc1cc(=O)o[nH]1.O=C(Cl)c1ccc(Cl)cc1Cl>>CCCc1cc(=O)on1C(=O)c1ccc(Cl)cc1Cl,,O=C([O-])O,[Na+],,,test
US20130096113A1,C=Cc1cnc2c(c1)ncn2Cc1ccc2nc(N[C@@H]3CCCC[C@H]3O)sc2c1>>CCc1cnc2c(c1)ncn2Cc1ccc2nc(N[C@@H]3CCCC[C@H]3O)sc2c1,[Ni],C1CCOC1,CO,,,test
US04414225,CCI.N#CC1=C(Cl)CCNCC1>>CCN1CCC(Cl)=C(C#N)CC1,,CCN(CC)CC,ClC(Cl)Cl,Cl,,test
US04010156,CC1(Cl)CSC2C(NC(=O)Cc3ccccc3)C(=O)N2C1C(=O)OCc1ccc([N+](=O)[O-])cc1>>CC1(Cl)CSC2C(NC(=O)Cc3ccccc3)C(=O)N2C1C(=O)O,[Pd],CCOC(C)=O,,,,test
US20050124605A1,COc1ccc(CCl)cc1.c1ccc(C2=NCCNc3ccccc32)cc1>>COc1ccc(CN2CCN=C(c3ccccc3)c3ccccc32)cc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20120046285A1,Cc1cc(Cl)c2cccc(OCc3ccccc3)c2n1.O>>Cc1cc(O)c2cccc(OCc3ccccc3)c2n1,,CS(C)=O,,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20100190831A1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.COc1ccc(C=O)cc1F>>CCOC(=O)/C=C/c1ccc(OC)c(F)c1,,Cc1ccccc1,,,,test
US06903238B2,COC(=O)c1ccc(OC)cc1.COc1ccc(CC#N)cc1>>COc1ccc(C2=C(N)c3cc(OC)ccc3C2=O)cc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20100222324A1,CCOC(=O)Cn1ccc2ccc([N+](=O)[O-])cc21>>CCOC(=O)Cn1ccc2ccc(N)cc21,[Fe],CCO,O,[Cl-].[NH4+],,test
US04218404,NCCCC(=O)N(CCS(=O)(=O)O)C(=O)OCc1ccccc1>>NCCCC(=O)NCCS(=O)(=O)O,[Pd],O,,,,test
US20100093730A1,FC(F)(F)c1ccc2c(c1)CNCC2.O=C(O)CN1CCCC(c2ccccc2)C1=O>>O=C(CN1CCCC(c2ccccc2)C1=O)N1CCc2ccc(C(F)(F)F)cc2C1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20050090541A1,CC(O)c1cn(C(=O)OC(C)(C)C)cn1>>CC(=O)c1cn(C(=O)OC(C)(C)C)cn1,O=[Mn]=O,ClCCl,,,,test
US20110207731A1,C[Si](C)(C)CCOCn1nc(I)c2cc(C3OCCO3)ccc21.OCCN1CCOCC1>>C[Si](C)(C)CCOCn1nc(OCCN2CCOCC2)c2cc(C3OCCO3)ccc21,,Cc1ccccc1,,,,test
US20130200341A1,Brc1ccc(-c2c3ccc4ccccc4c3nc3c2ccc2ccccc23)cc1.CC1(C)OB(c2ccc(-c3nc4ccccc4n3-c3ccccc3)cc2)OC1(C)C>>c1ccc(-n2c(-c3ccc(-c4ccc(-c5c6ccc7ccccc7c6nc6c5ccc5ccccc56)cc4)cc3)nc3ccccc32)cc1,,O,,O=C([O-])[O-].[K+].[K+],,test
US20160039794A1,C1COCCN1.CCCCCCC.Nc1nc(Cl)ccc1[N+](=O)[O-]>>Nc1cc(N2CCOCC2)ccc1[N+](=O)[O-],,CCCCCCC,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20160096827A1,CCn1cc(Nc2ncnc(-c3ccc(O[C@H]4CCNC[C@H]4F)c(C#N)c3)n2)c(C)n1.O=C(O)CO>>CCn1cc(Nc2ncnc(-c3ccc(O[C@H]4CCN(C(=O)CO)C[C@H]4F)c(C#N)c3)n2)c(C)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070299076A1,Br.O=C(O)CCC(F)(F)CCl>>O=C(O)CCC(F)(F)CBr,,C1COCCO1,CC(=O)O,Cl,,test
US20060223875A1,COc1ccc(C2(CN)CC2CO)cc1.O=S(Cl)Cl>>COc1ccc([C@@]23CNC[C@@H]2C3)cc1.Cl,,CC(Cl)Cl,,,,test
US20160016966A1,CC1(C)OB(c2ccnc(OCC3CCOCC3)c2)OC1(C)C.Cn1cc(Br)c2oc(CN3CCCC(F)(F)C3)cc2c1=O>>Cn1cc(-c2ccnc(OCC3CCOCC3)c2)c2oc(CN3CCCC(F)(F)C3)cc2c1=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,CCOC(C)=O,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US04291036,CCc1c(C)nc2cccc(C)n2c1=O.CI.Cl>>CCC1C(=O)N2C(C)CCCC2N(C)C1C.Cl,,CCO,O,CC(C)=O,,test
US20100280030A1,CN1CCN(CCCOC(=O)Nc2cccc(CO)c2)CC1.Cc1ccc2oc(=O)[nH]c2n1>>Cc1ccc2oc(=O)n(Cc3cccc(NC(=O)OCCCN4CCN(C)CC4)c3)c2n1,,CN(C)C=O,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20150094474A1,CC(=O)C1C(/C=C(\Cl)C(F)(F)F)C1(C)C.O=Cc1cccc(Oc2ccccc2)c1>>CC1(C)C(/C=C(\Cl)C(F)(F)F)C1C(=O)/C=C/c1cccc(Oc2ccccc2)c1,,CCO,,[Na+].[OH-],,test
US20110237517A1,COC(=O)N1CC(c2c[nH]c3cc(F)ccc23)C2C1CCN2C(=O)C(NC(=O)OC(C)(C)C)C1CCCCC1>>COC(=O)N1CC(c2c[nH]c3cc(F)ccc23)C2C1CCN2C(=O)C(N)C1CCCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060094767A1,CI.C[C@]1(CN2CCN(C(=O)Nc3ccc(C(F)(F)F)cc3)CC2)Cn2cc([N+](=O)[O-])nc2O1>>CN(C(=O)N1CCN(C[C@@]2(C)Cn3cc([N+](=O)[O-])nc3O2)CC1)c1ccc(C(F)(F)F)cc1,,O,,CN(C)C=O,[H-].[Na+],test
US20130115190A1,CC1(O)CCOC1.O=C(Oc1ccccn1)Oc1ccccn1>>CC1(OC(=O)Oc2ccccn2)CCOC1,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20070213364A1,COC(=O)CCc1ccc(OCc2ccc(CCl)cc2)cc1.c1ccc(-c2cc3ccccc3[nH]2)cc1>>COC(=O)CCc1ccc(OCc2ccc(Cn3c(-c4ccccc4)cc4ccccc43)cc2)cc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20150284384A1,CI.Cc1cc(C#N)cc2nc(CS(C)(=O)=O)c(CC3CCC(F)(F)CC3)n12>>Cc1cc(C#N)cc2nc(C(C)S(C)(=O)=O)c(CC3CCC(F)(F)CC3)n12,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20090131503A1,CCN(C(=O)OC(C)(C)C)C1CC=C(c2c[nH]c3ccc([N+](=O)[O-])cc23)CC1>>CCN(C(=O)OC(C)(C)C)C1CC=C(c2c[nH]c3ccc(N)cc23)CC1,[Ni],CO,,NN,O,test
US20090325903A1,CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B1OB([C@H](CC(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)c2cnccn2)OB([C@H](CC(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)c2cnccn2)O1.O=C(O)C[C@@H](O)C(=O)O>>CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B1OC(=O)[C@@H](CC(=O)O)O1,,CC(C)=O,,,,test
US20030060472A1,C1CCNC1.O=C(CCl)c1cc(O)c(O)c([N+](=O)[O-])c1>>Cl.O=C(CN1CCCC1)c1cc(O)c(O)c([N+](=O)[O-])c1,,CN(C)C=O,,,,test
US20140275084A1,CCOc1ccccc1CCOS(C)(=O)=O.NC(=O)c1ccnc(-c2c[nH]cn2)c1>>CCOc1ccccc1CCn1cnc(-c2cc(C(N)=O)ccn2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04585780,Cc1occc(=O)c1OCc1ccccc1.NCCO>>Cc1c(OCc2ccccc2)c(=O)ccn1CCO,,CCO,O,Cl,[Na+].[OH-],test
US04965270,CC1(C)OC[C@@H](COn2cnc3c(Cl)nc(N)nc32)O1>>Nc1nc(Cl)c2ncn(OC[C@@H](O)CO)c2n1,,CC(=O)O,,,,test
US20150031673A1,CC(C)(C)[Si](C)(C)Cl.N#Cc1cccc(Cl)n1.Nc1ccc(O)cc1>>CC(C)(C)[Si](C)(C)Oc1ccc(Nc2cccc(C#N)n2)cc1,,CN1CCCC1=O,O,c1c[nH]cn1,,test
US20100055071A1,CC1(C)OB(c2ccc(C(=O)NC3CC3)cc2)OC1(C)C.O=C(OCc1ccccc1)N1C(c2nc3cc(Br)ccc3[nH]2)CS[C@H]1c1ccncc1>>O=C(NC1CC1)c1ccc(-c2ccc3[nH]c(C4CS[C@@H](c5ccncc5)N4C(=O)OCc4ccccc4)nc3c2)cc1,,CO,,CN(C)C=O,O=C([O-])O.[Na+],test
US20150111885A1,CC1Cc2cc(Br)ccc2O1.CS(=O)O[Na]>>CC1Cc2cc(S(C)(=O)=O)ccc2O1,[Cu]I,CS(C)=O,,O=C(O)[C@@H]1CCCN1,O=C([O-])[O-].[K+].[K+],test
US07199257B1,CC1(Cl)OS(=O)OC1=C=O.N#Cc1ccc(N)cc1C(F)(F)F>>CC(O)(CO)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1,,ClCCl,,CCN(CC)CC,,test
US04495184,BrP(Br)Br.CC1CN(CC(C)C(O)c2ccc(C(C)(C)C)cc2)CC(C)O1>>CC1CN(CC(C)C(Br)c2ccc(C(C)(C)C)cc2)CC(C)O1,,c1ccncc1,,,,test
US20150284385A1,C=CC(C)=O.CO.COC(OC)OC>>COCCC(C)(OC)OC,,O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20160221972A1,COC(=O)c1ccc(C(=O)OC)c(OCCNC(=O)OC(C)(C)C)c1.O=C(O)C(F)(F)F>>COC(=O)c1ccc(C(=O)OC)c(OCCN)c1.O=C(O)C(F)(F)F,,CCOCC,CO,ClCCl,,test
US05318989,Cc1ccc(OS(=O)(=S)c2ccc(C)cc2)cc1.O=C1CCCCC1=O>>Cc1ccc(SC2=C(O)C(=O)CCC2)cc1,,C1CCOC1,,Cl,,test
US20120289495A1,CC(C)(C)OC(=O)N1CCNCC1.O=Cc1csc(-c2ccc(F)cc2)n1>>CC(C)(C)OC(=O)N1CCN(Cc2csc(-c3ccc(F)cc3)n2)CC1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20040122108A1,CO.Cc1cc(C)c(CC(=O)O)c(C)c1>>COC(=O)Cc1c(C)cc(C)cc1C,,Cl,,,,test
US20110275797A1,CC(=O)Oc1cc(Cl)ccc1C(=O)Nc1cc(-c2ccccc2)ccc1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1ccc(Cl)cc1O,,C1COCCO1,CO,O=C([O-])[O-].[K+].[K+],,test
US20070244131A1,CCOC(=O)OC(C)Cl.COc1nc(NCCc2ccc(Cl)cc2Cl)cc(-c2cccc(C(C)(C)C(=O)O)c2)n1>>CCOC(=O)OC(C)OC(=O)C(C)(C)c1cccc(-c2cc(NCCc3ccc(Cl)cc3Cl)nc(OC)n2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110071150A1,CCn1nc(-c2cccnc2)nc1-c1ccc([N+](=O)[O-])c(CC(O)c2c(Cl)cccc2Cl)c1>>CCn1nc(-c2cccnc2)nc1-c1ccc([N+](=O)[O-])c(CC(=O)c2c(Cl)cccc2Cl)c1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20090093462A1,Nc1ccc(I)cc1Cl.O=C(O)c1ccncc1F>>O=C(O)c1ccncc1Nc1ccc(I)cc1Cl,,C1CCOC1,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20120270857A1,Cl.O=C1C=C2C=NC=CN3NCC(=C23)C1CC12CCN(CC1)CC2>>Cl.O=C1C=C2C=NC=CN3NCC(=C23)C1CC12CCN(CC1)CC2,,CO,,,,test
US20130023518A1,COC(=O)c1ccc(N)cc1.O=Cc1ccc(Cl)c([N+](=O)[O-])c1>>COC(=O)c1ccc(/N=C/c2ccc(Cl)c([N+](=O)[O-])c2)cc1,,CCO,,,,test
US04212809,C=CCc1ccc2c(c1)OCO2.CCC(=O)OO>>c1cc2c(cc1CC1CO1)OCO2,,c1ccccc1,,,,test
US06437146B1,NS(=O)(=O)Cc1ccccc1.O=C(O)c1cccc(C[C@@H]2CCCC=C2c2nc(-c3ccccc3)c(-c3ccccc3)o2)c1>>O=C(NS(=O)(=O)Cc1ccccc1)c1cccc(C[C@@H]2CCCC=C2c2nc(-c3ccccc3)c(-c3ccccc3)o2)c1,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,Cl,test
US20030225071A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)[C@H]1N(c2cccc3c2C(c2ccccc2)c2ccccc2-3)CC(=O)C1(C)C>>COC(=O)[C@H]1N(C(=O)OC(C)(C)C)CC(=O)C1(C)C,[Pd],C1CCOC1,,[H][H],,test
US04556653,O=C1Nc2cccnc2N(C(=O)CCl)c2ccccc21.OCCCN1CCNCC1>>O=C1Nc2cccnc2N(C(=O)CN2CCN(CCCO)CC2)c2ccccc21,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20120264734A1,CC1(C)OB(c2cnn(CCN3CCOCC3)c2)OC1(C)C.Cc1cc(C)c(CNC(=O)c2cc(Br)cc(N(C)C3CCOCC3)c2C)c(=O)[nH]1>>Cc1cc(C)c(CNC(=O)c2cc(-c3cnn(CCN4CCOCC4)c3)cc(N(C)C3CCOCC3)c2C)c(=O)[nH]1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20110196009A1,CC(C)(C)OC(=O)NCC(C(=O)O)c1ccccc1.Cn1nccc1-c1c(Cl)sc(N)c1Cl>>Cn1nccc1-c1c(Cl)sc(NC(=O)C(CNC(=O)OC(C)(C)C)c2ccccc2)c1Cl,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US20020111367A1,CC(C)(C)C(=O)Cl.CN1CCN(c2ccc(N)cc2)CC1>>CN1CCN(c2ccc(NC(=O)C(C)(C)C)cc2)CC1,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,O,test
US06762180B1,CCN.O=[N+]([O-])c1ccc(CBr)cc1>>CCNCc1ccc([N+](=O)[O-])cc1,,CCO,,,,test
US20100286211A1,NO.O=Cc1cn(-c2ccc(Br)cn2)cn1>>ON=Cc1cn(-c2ccc(Br)cn2)cn1,,CCO,CO,Cl,,test
US05891889,CC(C)(C)OC(=O)N1CCC(CO)(Cc2cccc(OCc3ccccc3)n2)CC1>>CC(C)(C)OC(=O)N1CCC(CO)(Cc2cccc(O)n2)CC1,[Pd],CCO,,[H][H],,test
US06143751,OC(CCl)CCc1cccnc1.Oc1ccc2c(c1)OCCO2>>OC(CCc1cccnc1)COc1ccc2c(c1)OCCO2,,CCO,O,[Na+].[OH-],,test
US20060173008A1,CCn1nc(-c2ccccc2)c(C(C)=O)c([N+](=O)[O-])c1=O.Cc1cc2c(N)cccc2nn1>>CCn1nc(-c2ccccc2)c(C(C)=O)c(Nc2cccc3nnc(C)cc23)c1=O,,CCO,,,,test
US06043252,CN=Cc1ccc(/C=C/C(=O)N2CCc3c([nH]c4ccccc34)C2c2ccc3c(c2)OCO3)cc1>>CNCc1ccc(/C=C/C(=O)N2CCc3c([nH]c4ccccc34)C2c2ccc3c(c2)OCO3)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US05576343,CC(C)(C)OC(=O)N1CC[C@@H](O)C1.CCOC(=O)C(=O)c1ccc(O)cc1>>CCOC(=O)C(=O)c1ccc(O[C@H]2CCN(C(=O)OC(C)(C)C)C2)cc1,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090318441A1,C=CCNC(CC)CC.Clc1ncc(Br)c(Cl)n1>>C=CCN(c1nc(Cl)ncc1Br)C(CC)CC,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20020091264A1,CCOC(=O)Cc1cccc(NCC(=O)OC(C)(C)C)n1>>CCOC(=O)Cc1cccc(NC)n1,,C1COCCO1,,Cl,,test
US04052421,C#C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2O>>C#C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CCC2=O,,CC(C)=O,,O=S(=O)(O)O,O=[Cr](=O)=O,test
US20120309739A1,COc1nc(N2CCC(O)CC2)nc2oc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)c12>>COc1nc(N2CCC(O)CC2)nc2oc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130196978A1,O=C(CBr)c1ccccc1.O=C(O[C@H]1CN2CCC1CC2)[C@H](Nc1ccccc1)c1ccccc1>>O=C(C[N+]12CCC(CC1)[C@@H](OC(=O)[C@H](Nc1ccccc1)c1ccccc1)C2)c1ccccc1.[Br-],,CCOC(C)=O,,CCOCC,,test
US20020151561A1,C[C@@H](c1ccccc1)N1CCc2c(sc(N)c2C(=O)OC(C)(C)C)[C@@H]1CN.O=C=Nc1ccc(Oc2ccccc2)cc1>>C[C@@H](c1ccccc1)N1CCc2c(sc(N)c2C(=O)OC(C)(C)C)[C@@H]1CNC(=O)Nc1ccc(Oc2ccccc2)cc1,,ClCCl,,,,test
US06482986B1,CC(=O)OC(C)=O.Nc1cc(Cl)cc(Cl)c1>>CC(=O)Nc1cc(Cl)cc(Cl)c1,,ClC(Cl)Cl,,c1ccncc1,,test
US20020183327A1,CC(=O)Cl.Nc1ncc(Cl)cc1Cl.O=Cc1ccco1.[C-]#[N+]C1CCCCC1>>CC(=O)N(c1c(-c2ccco2)nc2c(Cl)cc(Cl)cn12)C1CCCCC1,,[O-][Cl+3]([O-])([O-])O,,,,test
US20130178460A1,CC(C)(C)OC(=O)N[C@H]1COCC[C@H]1N.Cn1cc(NC(=O)c2csc3cnc(Cl)nc23)cn1>>Cn1cc(NC(=O)c2csc3cnc(N[C@@H]4CCOC[C@@H]4NC(=O)OC(C)(C)C)nc23)cn1,,C1COCCO1,ClCCl,CCN(C(C)C)C(C)C,,test
US03975384,N#Cc1nc(N2CCNCC2)nc(Oc2ccccc2)c1Cl.O=S1CCNCC1>>N#Cc1nc(N2CCNCC2)nc(N2CCS(=O)CC2)c1Cl,,O,,,,test
US20080167287A1,CN.O=C(O)c1ccc(-c2cnc3ncc(C4(c5ccc6ncccc6c5)CC4)n3c2)cc1Cl>>CNC(=O)c1ccc(-c2cnc3ncc(C4(c5ccc6ncccc6c5)CC4)n3c2)cc1Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20100075983A1,COC(=O)C=C1COC1.C[Mg]Cl>>COC(=O)CC1(C)COC1,[Cu]I,C1CCOC1,,C[Si](C)(C)Cl,,test
US20150166507A1,C#CCNC(=O)c1cccnc1Cl.COc1ccc(N)cc1>>C#CCNC(=O)c1cccnc1Nc1ccc(OC)cc1,,OCCO,,,,test
US20130072492A1,CI.COC(=O)Cc1ccccn1>>COC(=O)C(C)c1ccccn1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20040138277A1,CCOC(=O)C(C)(Cc1ccc(O)cc1)Oc1ccc(C)c(C)c1.Cc1ccc(S(=O)(=O)OCCc2nc(-c3ccc(-c4ccccc4)cc3)oc2C)cc1>>Cc1ccc(OC(C)(Cc2ccc(OCCc3nc(-c4ccc(-c5ccccc5)cc4)oc3C)cc2)C(=O)O)cc1C,,CCO,,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20110034452A1,CN=C=S.Cc1c(Cl)nnc(NN)c1C>>CNC(=S)NNc1nnc(Cl)c(C)c1C,,ClCCl,,,,test
US05714471,CCCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)OCC.[OH-]>>CCCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)O,,CO,,Cl,,test
US20020045758A1,C=CC#N.CS(=O)c1c(C=NO)nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1N>>CS(=O)c1c(C=NOCCC#N)nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1N,,CCO,,C,C[O-].[Na+],test
US20160194290A1,C=CC(C(C)C)C(C)(C(=O)O)c1ccc(CCC(C)(C)C)c(Cl)c1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>C=CC(C(C)C)C(C)(N=C=O)c1ccc(CCC(C)(C)C)c(Cl)c1,,Cc1ccccc1,,CCN(CC)CC,,test
US20140304842A1,CC(C)(C)OC(=O)Nc1ccc2cc(N)ccc2c1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)Nc1ccc2c(Br)c(N)ccc2c1,,CC#N,,C,O=C[O-].[NH4+],test
US20100076046A1,COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(CN(C)CCN(C)CCCS(=O)(=O)NC(=O)OC(C)(C)C)N(C)c1ccccc1-3>>COC(=O)c1ccc2c(C3CCCCC3)c3n(c2c1)CC(CN(C)CCN(C)CCCS(N)(=O)=O)N(C)c1ccccc1-3,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150320702A1,CN.O=C1C=C(Br)C(=O)c2ccccc21>>CNC1=CC(=O)c2ccccc2C1=O,,CCO,,,,test
US20140073792A1,CC(O)C(C)(C)c1ncccc1Oc1cnc2c(F)cccc2c1>>CC(=O)C(C)(C)c1ncccc1Oc1cnc2c(F)cccc2c1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US06218376B1,CC(C)(C)Oc1ncc(Br)c(OC(C)(C)C)n1.CCc1ccc2c(c1)CCc1oc(C)nc1C2=O>>CCc1ccc2c(c1)CCc1oc(C)nc1C2(O)c1cnc(OC(C)(C)C)nc1OC(C)(C)C,,C1CCOC1,,[Li]CCCC,,test
US05155250,CCc1cc(CBr)cc(CC)c1O.C[Si](C)(C)CCl>>CCc1cc(CC[Si](C)(C)C)cc(CC)c1O,,CCOCC,,[Mg],,test
US20070293558A1,CCOC(=O)CBr.COc1ccc2c(c1)[nH]c1ccccc12>>COc1ccc2c3ccccc3n(CC(=O)O)c2c1,,CN(C)C=O,O,[Na+].[OH-],,test
US20100256097A1,Cc1nc(Cl)ccc1C(C)N(C(=O)[O-])C(=O)OC(C)(C)C>>COC(=O)NCc1ccc(Cl)nc1C,,ClCCl,O=C(O)C(F)(F)F,,,test
US20150175604A1,Cc1cc2c(ccc3nnc(C)n32)[nH]1.ICC1CCCC1>>Cc1cc2c(ccc3nnc(C)n32)n1CC1CCCC1,,CN(C)C=O,,[H-].[Na+],,test
US20070105904A1,COc1cccc(CCl)n1.Nc1ccc(-c2cc(Cc3ccc(O)cc3)no2)c(N)n1>>COc1cccc(COc2ccc(Cc3cc(-c4ccc(N)nc4N)on3)cc2)n1,,CN(C)C=O,,C1CCOC1,[Na+].[OH-],test
US20130281452A1,C1COCCN1.COc1cc(F)cc(O)c1[N+](=O)[O-]>>COc1cc(N2CCOCC2)cc(O)c1[N+](=O)[O-],,CS(C)=O,O,,,test
US20070142362A1,CCCCCC1=NN(C(=O)Cl)CC1c1ccccc1.COc1ccc(N)cc1>>CCCCCC1=NN(C(=O)Nc2ccc(OC)cc2)CC1c1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080214654A1,COc1cc(CNCCNC(=O)OC(C)(C)C)ccc1OCc1ccccc1F.O=C(Cl)c1cccs1>>COc1cc(CN(CCNC(=O)OC(C)(C)C)C(=O)c2cccs2)ccc1OCc1ccccc1F,,ClCCl,,CCN(CC)CC,,test
US20110311474A1,CCC1CC(C(=O)OC)CC1C(=O)OC(C)(C)C>>CCC1CC(CO)CC1C(=O)OC(C)(C)C,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120071461A1,Brc1ccncc1.C1CC2(CCN1)OCCO2>>c1cc(N2CCC3(CC2)OCCO3)ccn1,,CCCCO,,CCN(C(C)C)C(C)C,Cl,test
US20080058383A1,CCC[C@@H](N)CO.N#Cc1ccc(F)cc1C(F)(F)F>>CCC[C@H](CO)Nc1ccc(C#N)c(C(F)(F)F)c1,,CS(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20030040521A1,CCCOC1=Nc2sccc2C(=CN)N1CCC.O=C1CCC(=O)N1Br>>CCCOC1=Nc2sc(Br)cc2C(=CN)N1CCC,,c1ccncc1,,,,test
US04369139,COc1ccc(C(=O)Oc2c(Cl)c(Cl)c(Cl)c(Cl)c2Cl)cc1.O=C1CCCN1>>COc1ccc(C(=O)N2CCCC2=O)cc1,,CN(C)C=O,,[Na],,test
US20130237533A1,CC(C)(C)OC(=O)NCCN.Clc1ncc(Br)c(Cl)n1>>CC(C)(C)OC(=O)NCCNc1nc(Cl)ncc1Br,,CCO,,CCN(C(C)C)C(C)C,,test
US20030130505A1,Nc1ccc2[nH]c(=O)cc(C(F)(F)F)c2c1.O=N[O-]>>NNc1ccc2[nH]c(=O)cc(C(F)(F)F)c2c1,,Cl,O,Cl[Sn]Cl,,test
US20070060577A1,CCN.CCOC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(Nc3cccc(C(=O)N(C)C)c3)ncc2c1=O>>CCNC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(Nc3cccc(C(=O)N(C)C)c3)ncc2c1=O,,CO,,,,test
US20110306588A1,CC(C)(C)OC(=O)N1CCC(Oc2ncccc2C2=CCOCC2)CC1>>CC(C)(C)OC(=O)N1CCC(Oc2ncccc2C2CCOCC2)CC1,[Pd],CO,,,,test
US05252586,O=C(Cl)c1ccccc1.OCCC1CCNCC1>>O=C(c1ccccc1)N1CCC(CCO)CC1,,ClCCl,,CCN(CC)CC,,test
US20120142671A1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1N.N#Cc1ccc(F)cc1Br>>CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1ccc(C#N)c(Br)c1,,CS(C)=O,O,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US05281614,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCCCc1nn(-c2cc([N+](=O)[O-])ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(N)(=O)=O)cc1>>CCCCc1nn(-c2cc([N+](=O)[O-])ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)cc1,,CO,,ClCCl,,test
US20100298373A1,Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(C(=O)OC(C)(C)C)C2CCCC(=O)O.O=C(O)C(F)(F)F>>Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCNC2CCCC(=O)O.O=C(O)C(F)(F)F,,ClCCl,,,,test
US06114352,CC(=O)Oc1c(O)c2ccc([N+](=O)[O-])cc2n(C)c1=O.COCCl>>COCOc1c(OC(C)=O)c(=O)n(C)c2cc([N+](=O)[O-])ccc12,,C1CCOC1,,CCN(CC)CC,,test
US20100222343A1,N#Cc1cccc(Br)c1.OO>>NC(=O)c1cccc(Br)c1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060276508A1,COC(=O)c1cccc(OS(C)(=O)=O)c1>>CS(=O)(=O)Oc1cccc(C(=O)O)c1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20150232452A1,CCn1cc(-c2cccc(N)c2)c(-c2ccncc2)n1.O=C=Nc1cccc(I)c1>>CCn1cc(-c2cccc(NC(=O)Nc3cccc(I)c3)c2)c(-c2ccncc2)n1,,ClCCl,,,,test
US20160002177A1,COc1cc(Br)c(C(F)(F)F)c2c(=O)[nH]cnc12.OB(O)c1ccc(F)cc1>>COc1cc(-c2ccc(F)cc2)c(C(F)(F)F)c2c(=O)[nH]cnc12,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20080200523A1,NN.O=C1NC(=O)C2(Cc3cccc(COc4ccc(Cl)cc4)c3)C=CC=CC12>>NCc1cccc(COc2ccc(Cl)cc2)c1,,C1CCOC1,CCO,O,,test
US20050208582A1,CCOC(=O)c1ccc2[nH]nc(/C=C/c3ccc(F)cc3)c2c1OCCC(N)=O>>NC(=O)CCOc1c(C(=O)O)ccc2[nH]nc(/C=C/c3ccc(F)cc3)c12,,O=S(=O)(O)O,,,,test
US20160068559A1,CC(C)N(CCCN1C(=O)c2ccccc2C1=O)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21>>CC(C)N(CCCN)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21,,CCO,,NN,O,test
US20130289027A1,BrCCOCCBr.COC(=O)C(OC(C)(C)C)c1c(-c2ccc(C)c(C)c2)c2ccc(CN)cc2c(=O)n1C>>COC(=O)C(OC(C)(C)C)c1c(-c2ccc(C)c(C)c2)c2ccc(CN3CCOCC3)cc2c(=O)n1C,,CCOC(C)=O,Cc1ccccc1,CCN(C(C)C)C(C)C,,test
US20080281105A1,CC[n+]1c(C)ccc2cc(N(C)C)ccc21.Cc1cc(C=O)c(C)n1-c1ccccc1.O=S(=O)([O-])C(F)(F)F>>CC[n+]1c(/C=C/c2cc(C)n(-c3ccccc3)c2C)ccc2cc(N(C)C)ccc21.O=S(=O)([O-])C(F)(F)F,C1CCNCC1,CO,,,,test
US06136823,CC(C)I.O=C(O)c1cc(F)c(F)c(O)c1F>>CC(C)Oc1c(F)c(F)cc(C(=O)O)c1F,,CCO,,O,[Na+].[OH-],test
US04558043,CC(=O)CCl.Cc1ccc(O)cc1[N+](=O)[O-]>>CC(=O)COc1ccc(C)c([N+](=O)[O-])c1,,CN(C)C=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20150352082A1,COc1cc(CC(=O)Cl)cc(OC)c1OC.Nc1nc2ccc(OC(F)(F)F)cc2s1>>COc1cc(CC(=O)Nc2nc3ccc(OC(F)(F)F)cc3s2)cc(OC)c1OC,,C1CCOC1,,,,test
US20070203210A1,CCOC(=O)c1sc(Cl)nc1-c1ccccc1.COc1cc2nc[nH]c2cc1OC>>CCOC(=O)c1sc(-n2cnc3cc(OC)c(OC)cc32)nc1-c1ccccc1,,CN1CCCC1=O,,O,[H-].[Na+],test
US04880902,ClCCCl.c1ccc(P(CP(c2ccccc2)c2ccccn2)c2ccccn2)cc1>>c1ccc(P(CCP(c2ccccc2)c2ccccn2)c2ccccn2)cc1,,ClCCCl,,ClCCl,,test
US20060094750A1,O=[N+]([O-])c1cc(Br)cnc1NCC1CCOCC1>>Nc1cc(Br)cnc1NCC1CCOCC1,[Pt],C1CCOC1,CO,,,test
US20040063946A1,Cc1cccc(-c2nc(N)sc2-c2ccnc(NC3CCCC3)c2)c1.O=C=Nc1ccccc1>>Cc1cccc(-c2nc(NC(=O)Nc3ccccc3)sc2-c2ccnc(NC3CCCC3)c2)c1,,CC(=O)N(C)C,,O=C([O-])O.[Na+],,test
US20120190701A1,COCCCc1cc(CCCOC)c(Cl)c(C(=O)OC)c1>>COCCCc1cc(CO)c(Cl)c(CCCOC)c1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120283261A1,CN1CCN(Cc2ccc(N)cc2)CC1.O=S(=O)(c1cc(F)ccc1Nc1nc(Cl)ncc1Cl)N1CCCC1>>CN1CCN(Cc2ccc(Nc3ncc(Cl)c(Nc4ccc(F)cc4S(=O)(=O)N4CCCC4)n3)cc2)CC1,,CO,ClCCl,,,test
US20100261679A1,CNC(=O)c1cc(Oc2ccc3nc(S(C)(=O)=O)ncc3c2)ccn1.[N-]=[N+]=[N-]>>CNC(=O)c1cc(Oc2ccc3nc(N=[N+]=[N-])ncc3c2)ccn1,,CN1CCCC1=O,,O,,test
US20090186879A1,CCOC(=O)CCCNc1c([N+](=O)[O-])cccc1[N+](=O)[O-]>>CCOC(=O)CCCNc1c(N)cccc1N,[Pd],C1CCOC1,,,,test
US20030144329A1,C=O.CC1(C)CCC(C)(C)c2cc(N)ccc21.[BH3-]C#N>>CN(C)c1ccc2c(c1)C(C)(C)CCC2(C)C,,CC#N,,CC(=O)O,,test
US05512431,Nc1nc2c(nc(OCc3ccccc3)n2[C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1>>Nc1nc2c(nc(O)n2[C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1,[Pd],CO,O,,,test
US20110274638A1,CC#CCOC1(c2ccccc2C)CN(C(=O)[C@@H](Cc2ccc(OC)cc2)NC(=O)OC(C)(C)C)C1>>CC#CCOC1(c2ccccc2C)CN(C(=O)[C@H](N)Cc2ccc(OC)cc2)C1,,CCOC(C)=O,,Cl,,test
US20030087952A1,C#Cc1ccccc1.CN1C(=O)C[C@H](c2ccccc2)[C@@H]1C=O>>CN1C(=O)C[C@H](c2ccccc2)[C@@H]1[C@H](O)C#Cc1ccccc1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20030073862A1,CO.Nc1ccc(O)cc1C(=O)O>>COC(=O)c1cc(O)ccc1N,,CO,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US06214881B1,COc1ccc(S(=O)(=O)NC(=O)c2cccc([N+](=O)[O-])c2)cc1>>COc1ccc(S(=O)(=O)NC(=O)c2cccc(N)c2)cc1,[Pd],CCO,,,,test
US20150152127A1,C=CCO[C@@H]1[C@H]2N=C(N(CC)C(=O)OC(C)(C)C)S[C@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@H]1OCC=C>>C=CCO[C@@H]1[C@H]2N=C(N(CC)C(=O)OC(C)(C)C)S[C@H]2O[C@H](CO)[C@H]1OCC=C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100292215A1,CCOC(=O)c1ccc(OC2CCC(N)CC2)cc1.O=C(Cl)C1CC1>>CCOC(=O)c1ccc(OC2CCC(NC(=O)C3CC3)CC2)cc1,,ClCCl,,O,,test
US20100137281A1,N#Cc1ccccc1-c1ccc(Cn2c(=O)n(CC(=O)C3CCCCC3)c(=O)c3cc(CC(F)(F)F)sc32)cc1.O=C([O-])O.[NH3+]O>>O=C(Cn1c(=O)c2cc(CC(F)(F)F)sc2n(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c1=O)C1CCCCC1,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US20130344030A1,CC=O.COC(=O)C1CCSCC1>>COC(=O)C1(C(C)O)CCSCC1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20100137588A1,CN(C)[c-]1cccc1I.OB(O)c1ccccc1.[Fe+2].c1cc[cH-]c1>>CN(C)[c-]1cccc1-c1ccccc1.[Fe+2].c1cc[cH-]c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,[Na+].[OH-],,test
US03969351,Cc1ccsc1C=O.Nc1cc([N+](=O)[O-])ccc1O>>Cc1ccsc1C=Nc1cc([N+](=O)[O-])ccc1O,,CCO,,,,test
US20060217382A1,COc1ccc(CCNC(C)=O)cc1Nc1ncc2c(C)nc(-c3cccc(C(F)(F)F)c3)n2n1>>COc1ccc(CCN)cc1Nc1ncc2c(C)nc(-c3cccc(C(F)(F)F)c3)n2n1,,Cl,,,,test
US20040082571A1,Clc1ccc(N2CCNCC2)cc1.O=C(Cl)CCl>>O=C(CCl)N1CCN(c2ccc(Cl)cc2)CC1,,CCCCCC,CCOC(C)=O,CCN(CC)CC,ClCCl,test
US20140343079A1,CCOC(=O)/C=C/c1cc(-c2cc3c(cc2C)C(C)(C)CCC3(C)C)c(C)cn1>>Cc1cnc(/C=C/C(=O)O)cc1-c1cc2c(cc1C)C(C)(C)CCC2(C)C,,CO,O,Cl,[K+].[OH-],test
US20120184574A1,COC(=O)c1c(B(O)O)n(C2CCCC2)c2cc(C)c(F)cc12.C[C@H](NS(=O)(=O)c1ccc(Cl)nc1)C(F)(F)F>>COC(=O)c1c(-c2ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn2)n(C2CCCC2)c2cc(C)c(F)cc12,,CC#N,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20150210688A1,CCOC(=O)c1nc(C)c[nH]1.O=C1CCC(=O)N1I>>CCOC(=O)c1nc(C)c(I)[nH]1,,CC#N,,,,test
US20150057273A1,CC(C)(C)S[C@H]1C[C@@H](O)c2ccccc21.O=C1NC(=O)c2ccccc21>>CC(C)(C)S[C@@H]1C[C@@H](N2C(=O)c3ccccc3C2=O)c2ccccc21,O,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04962109,CC(C)(C)c1ncc(C(C(=O)O)C(C)(C)C)cn1.COCc1c(F)c(F)c(CO)c(F)c1F>>COCc1c(F)c(F)c(COC(=O)C(c2cnc(C(C)(C)C)nc2)C(C)(C)C)c(F)c1F,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20050261350A1,COc1ccc(C(=O)Nc2cc3c(cc2[N+](=O)[O-])N(CCC(C)C)C(=O)C3(C)C)cc1>>COc1ccc(-c2nc3cc4c(cc3[nH]2)C(C)(C)C(=O)N4CCC(C)C)cc1,[Ni],,,,,test
US20130102600A1,O=C(NOC1CCCCO1)c1ccc(-c2ccccc2)cn1>>O=C(NO)c1ccc(-c2ccccc2)cn1,,C1COCCO1,,,,test
US20100179122A1,Nc1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccccc1.O=C=Nc1ccccc1F>>NC(=O)N(c1ccccc1F)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090181942A1,CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2Cl)c2cc(Br)ccc2NC1=O.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2Cl)c2cc(Br)ccc2NC1=S,,C1CCOC1,CCOC(C)=O,O=C([O-])O.[Na+],,test
US20100280030A1,COC(=O)c1cccc(-c2ncc(N=CN(C)C)cn2)c1.O=S(=O)(O)O>>O=C(O)c1cccc(-c2ncc(O)cn2)c1,,O,,,,test
US20090093483A1,CC1(C)C(=O)C=C(O)c2cc(Br)ccc21.COC(=O)CCC(=O)Cl>>COC(=O)CCC(=O)OC1=CC(=O)C(C)(C)c2ccc(Br)cc21,,ClCCCl,ClCCl,,,test
US20130217668A1,COC(=O)[C@@H]1CC[C@H](Nc2cc(CO[Si](C(C)C)(C(C)C)C(C)C)ccc2N)CC1.N#CBr>>COC(=O)[C@@H]1CC[C@H](n2c(N)nc3ccc(CO[Si](C(C)C)(C(C)C)C(C)C)cc32)CC1,,ClCCl,,CCO,,test
US05576321,O=C(O)C(=O)O.c1cc(OC[C@@H]2CO2)c2cc[nH]c2c1.c1ccc(C2(c3ccccc3)CCNCC2)cc1>>O=C(O)C(=O)O.O[C@H](COc1cccc2[nH]ccc12)CN1CCC(c2ccccc2)(c2ccccc2)CC1,,CCOC(C)=O,,CO,,test
US04622401,N#CC=Cc1ccccc1.NNc1ccccn1>>NC1=NN(c2ccccn2)C(c2ccccc2)C1,,CCO,,[Na],,test
US20120252758A1,C[C@H](N)CO.Cc1cn(-c2ccc3n(c2=O)CCOC3=O)cn1>>Cc1cn(-c2ccc(C(=O)N[C@@H](C)CO)n(CCO)c2=O)cn1,,CC#N,,,,test
US20100113440A1,C=CCCCCN(C)C(=O)C1CC(Oc2ccnc(Cl)n2)CC1C(=O)NC1(C(=O)NS(=O)(=O)C2CC2)CC1C=C.OB(O)c1ccccc1>>C=CCCCCN(C)C(=O)C1CC(Oc2ccnc(-c3ccccc3)n2)CC1C(=O)NC1(C(=O)NS(=O)(=O)C2CC2)CC1C=C,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,,,test
US20080262004A1,Nc1ccnn1-c1ccccc1.O=CC(Br)C=O>>Brc1cnc2c(cnn2-c2ccccc2)c1,,CC(=O)O,,,,test
US04336378,CCc1noc(C)c1-c1[nH]c2ccccc2c1CC(=O)Cl.CNC>>CCc1noc(C)c1-c1[nH]c2ccccc2c1CC(=O)N(C)C,,O,,C1CCOC1,,test
US20150210688A1,COC(=O)c1cc(-c2[nH]c(CO)nc2C#N)c(C)cc1C>>Cc1cc(C)c(-c2[nH]c(CO)nc2C#N)cc1C(=O)O,,CO,O,[Na+].[OH-],,test
US20060166991A1,O=C(Cl)C(=O)Cl.O=C(O)c1cnccc1C(F)(F)F>>O=C(Cl)c1cnccc1C(F)(F)F,,ClCCl,,CN(C)C=O,,test
US20160016948A1,CC(C)n1cnc2cnc(Nc3ccnc(N4CC5(CN(C(=O)OC(C)(C)C)C5)C4)n3)cc21.Cl>>CC(C)n1cnc2cnc(Nc3ccnc(N4CC5(CNC5)C4)n3)cc21.Cl,,ClCCl,,,,test
US20030004181A1,COC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)N)cc1)n2C)c1ccccn1.O=C(Cl)c1ccccc1>>COC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)NC(=O)c3ccccc3)cc1)n2C)c1ccccn1,,CO,ClCCl,Cl,,test
US20160122341A1,Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(-c3cnn(CC(C)(C)N)c3)n2c1.Cl>>Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(-c3cnn(CC(C)(C)N)c3)n2c1.Cl,,CCOCC,,,,test
US20100273833A1,COCCCn1c(SC)nc(-c2ccc(F)cc2)c1-c1ccnc(NC(C)=O)c1>>COCCCn1c(SC)nc(-c2ccc(F)cc2)c1-c1ccnc(N)c1,,Cl,,[Na+].[OH-],,test
US20150157622A1,CC(=O)OC(C)=O.CCOC(=O)Oc1c(OC)cc(C(=O)O[C@@H]2C[C@@H]3CN4CCc5c([nH]c6cc(O)ccc56)[C@H]4C[C@@H]3[C@H](C(=O)OC)[C@H]2OC)cc1OC>>CCOC(=O)Oc1c(OC)cc(C(=O)O[C@@H]2C[C@@H]3CN4CCc5c([nH]c6cc(OC(C)=O)ccc56)[C@H]4C[C@@H]3[C@H](C(=O)OC)[C@H]2OC)cc1OC,CN(C)c1ccncc1,ClCCl,,,,test
US20100297020A1,CCOP(=O)(CO)OCC.O=S(=O)(Cl)c1ccc(Cl)cc1>>CCOP(=O)(COS(=O)(=O)c1ccc(Cl)cc1)OCC,,CCOCC,,CCN(CC)CC,,test
US05212164,C#C.C1CCOC1.CCCCCC.CCOC(C)=O.COC(=O)Cl.[Li]CCCC>>COC(=O)C#CCC/C=C(\C)CCC=C(C)C,,C1CCOC1,,,,test
US06191164B1,CC1(C)CC(=O)c2ccccc2O1.NO>>CC1(C)CC(=NO)c2ccccc2O1,,CO,c1ccncc1,Cl,,test
US04118583,CC(C)(Oc1ccc(Cl)cc1)C(=O)Cl.CC(O)Cl>>CC(C)(Oc1ccc(Cl)cc1)C(=O)OCCCl,,CCN(CC)CC,,C1CCOC1,,test
US04824848,CCCCn1c(=O)cc(NN)n(Cc2ccccc2)c1=O.CN=C=S>>CCCCn1c(=O)c2c(NC)n[nH]c2n(Cc2ccccc2)c1=O,,CN(C)C=O,,CO,,test
US20150210722A1,C[Si](C)(C)c1cc(C(=O)O)n(-c2ccc(P(C)(C)=O)cc2)n1.Nc1ccc(Oc2ccnc(Nc3ccccc3)n2)c2ccccc12.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>C[Si](C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccccc4)n3)c3ccccc23)n(-c2ccc(P(C)(C)=O)cc2)n1,,CN(C)C=O,,CCN(CC)CC,,test
US20150133438A1,Cn1cc(Br)cn1.O=C1C[C@H]2CSC(NC(=O)c3ccccc3)=N[C@@]2(c2ccc(F)cc2F)CO1>>Cn1cc(C2(O)C[C@H]3CSC(NC(=O)c4ccccc4)=N[C@@]3(c3ccc(F)cc3F)CO2)cn1,,C1CCOC1,,[Li]CCCC,,test
US20160096791A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)=CCC(CN)(c1ccccc1)c1ccccc1>>CC(C)=CCC(CNC(=O)OC(C)(C)C)(c1ccccc1)c1ccccc1,,ClCCl,,CCN(CC)CC,[Cl-].[NH4+],test
US20050137226A1,Cl.c1ccc(Oc2ccc(OC3CN4CCC3CC4)nc2)cc1>>Cl.c1ccc(Oc2ccc(OC3CN4CCC3CC4)nc2)cc1,,CCOC(C)=O,,C1COCCO1,,test
US20060014948A1,COCCOCOc1cc(CC2CNCCN2)ccc1C.O=C(Cl)OCc1ccccc1.O=C(Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>COCCOCOc1cc(CC2CN(C(=O)OCc3ccccc3)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)ccc1C,,ClCCl,,CCN(CC)CC,,test
US20080027092A1,Cc1cc2c(-c3ccccc3)nccc2n1C(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>Cc1cc2c(-c3ccccc3)nccc2[nH]1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20060199956A1,CO.CSCCOC(C)C(=O)O>>COC(=O)C(C)OCCSC,,CO,,O=C(Cl)C(=O)Cl,,test
US20080027049A1,CC(C)(C)c1ccc(C(=O)Cl)cc1.NC1CCc2oc3ccccc3c2C1>>CC(C)(C)c1ccc(C(=O)Nc2ccc3oc4c(c3c2)CCCC4)cc1,,C1CCOC1,,CCN(CC)CC,,test
US04495372,O=[N+]([O-])O.c1ccc2ccccc2c1>>O=[N+]([O-])c1cccc2ccccc12,,O,,,,test
US20070167449A1,COc1ccc(Nc2ncc(-c3ccc(OC)cc3)s2)cc1.NC(=S)Nc1ccccc1>>COc1ccc(-c2cnc(Nc3ccccc3)s2)cc1,,CO,ClCCl,,,test
US20060128793A1,CNCCCN(C)C.COC[C@H]1OC(=O)c2coc3c2[C@@]1(C)C1=C(C3=O)[C@@H]2CC[C@H](O)[C@@]2(C)C[C@H]1OC(C)=O>>COC[C@H]1OC(=O)/C(=C/N(C)CCCN(C)C)C2=C(O)C(=O)C3=C([C@H](OC(C)=O)C[C@@]4(C)C3CC[C@@H]4O)[C@]21C,,ClCCl,,,,test
US20150080549A1,CCSSCC.Cc1cccc(SSc2cccc(C)c2O)c1O>>CCSSc1cccc(C)c1O,,ClCCl,,CCOCC,FB(F)F,test
US20120238599A1,C=COCCON.Cn1c(Nc2ccc(I)cc2F)c(C(=O)O)c2occc2c1=O>>C=COCCONC(=O)c1c(Nc2ccc(I)cc2F)n(C)c(=O)c2ccoc12,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US05616706,CC(C)OC(=O)Cn1c(=O)n(C)c(=O)n(-c2ccc(F)cc2Cl)c1=O.O=[N+]([O-])O>>Cn1c(=O)n(CC(=O)O)c(=O)n(-c2cc([N+](=O)[O-])c(F)cc2Cl)c1=O,,O=S(=O)(O)O,,,,test
US20120295884A1,O=C(O)c1ccc(F)cc1.O=[N+]([O-])O>>O=C(O)c1ccc(F)c([N+](=O)[O-])c1,,O=S(=O)(O)O,,,,test
US06610692B1,CCOC(=O)Cn1c(C)cc(O)c(C(C)=O)c1=O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)Cn1c(C)cc(OS(=O)(=O)C(F)(F)F)c(C(C)=O)c1=O,,ClCCl,O,c1ccncc1,,test
US20140088101A1,CC(C)(C)OC(=O)C(C)(C)CN.COC(=O)c1ncc2c(cc(-c3ccccc3)c(=O)n2Cc2ccccc2)c1O>>CC(C)(C)OC(=O)C(C)(C)CNC(=O)c1ncc2c(cc(-c3ccccc3)c(=O)n2Cc2ccccc2)c1O,,CCO,,,,test
US20080032988A1,BrBr.c1cc2cnc(CCN3CCOCC3)nc2s1>>Brc1cc2cnc(CCN3CCOCC3)nc2s1,,ClCCl,,,,test
US20160016966A1,CC(N)c1ccccc1.Clc1cc(Br)ccn1>>CC(Nc1cc(Br)ccn1)c1ccccc1,,CCO,,CCN(C(C)C)C(C)C,,test
US04734418,CCNC(=O)c1cnc(N2CCN(Cc3ccccc3)CC2)nc1C.CN(C)C=O>>CCn1ccc2nc(N3CCN(Cc4ccccc4)CC3)ncc2c1=O,,CN(C)C=O,,CCCCCC,[H-].[Na+],test
US20040192767A1,COCCC(=O)O.Cc1oc(S(N)(=O)=O)cc1COc1ccc(-c2ccccc2)cc1>>COCCC(=O)NS(=O)(=O)c1cc(COc2ccc(-c3ccccc3)cc2)c(C)o1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140243316A1,COc1ccc(C=O)c(OC)c1.C[C@@H](O)CN>>COc1ccc(CNC[C@@H](C)O)c(OC)c1,,C1CCOC1,CCOC(C)=O,CC(=O)O,[Na+].[OH-],test
US20100150831A1,COC(=O)CCCOc1c(C)cc2cccnc2c1N1CCCNCC1.O=Cc1csc(N2CCC(O)CC2)n1>>COC(=O)CCCOc1c(C)cc2cccnc2c1N1CCCN(Cc2csc(N3CCC(O)CC3)n2)CC1,,ClCCCl,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US05719155,CC(=O)c1cc(C#N)ccc1O.COCC(=O)COC>>COCC1(COC)CC(=O)c2cc(C#N)ccc2O1,,Cc1ccccc1,,C1CCNC1,,test
US20150087639A1,CC(=O)NC(C)(C)Cc1ccc(Cl)c(F)c1>>CC(C)(N)Cc1ccc(Cl)c(F)c1,,Cl,,[Na+].[OH-],,test
US20060025474A1,C=CCc1ccc(C(CC)(CC)c2ccc(CCC(O)C(C)(C)C)c(C)c2)cc1C.CC[Si](Cl)(CC)CC>>C=CCc1ccc(C(CC)(CC)c2ccc(CCC(O[Si](CC)(CC)CC)C(C)(C)C)c(C)c2)cc1C,,O,,CN(C)C=O,c1c[nH]cn1,test
US20050070582A1,CN(c1cc(Cl)cc(Cl)c1)c1ccc(C#N)cc1S(=O)(=O)N1CCN(C(=O)OC(C)(C)C)CC1.Cl>>CN(c1cc(Cl)cc(Cl)c1)c1ccc(C#N)cc1S(=O)(=O)N1CCNCC1.Cl,,C1COCCO1,,,,test
US20040110811A1,CC1(c2ccccc2)NC(=O)N(C(=O)c2cccc3ccccc23)C1=O.O=C(CBr)c1ccccc1>>CC1(c2ccccc2)C(=O)N(C(=O)c2cccc3ccccc23)C(=O)N1CC(=O)c1ccccc1,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20100267769A1,CC(C)(c1ccc2cc(C(=O)O)ccc2n1)C(F)(F)F.CCn1ncc(C(C)N)c1C>>CCn1ncc(CNC(=O)c2ccc3nc(C(C)(C)C(F)(F)F)ccc3c2)c1C,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070179115A1,CCOC(=O)CCCCOc1cc(-c2ccccc2)ccc1CNc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O>>Nc1ncnc2c1nc(NCc1ccc(-c3ccccc3)cc1OCCCCC(=O)O)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O,,CO,,[Na+].[OH-],,test
US20100120840A1,CC(Br)c1ccccc1.Nc1cnc2[nH]c(-c3ccccc3)nc2c1>>CC(Nc1cnc2[nH]c(-c3ccccc3)nc2c1)c1ccccc1,,CN(C)C=O,,,,test
US07071189B2,FC(F)c1nc2ccccc2n1-c1nc(N2CCOCC2)nc(N2CCSCC2)n1.O=C(OO)c1cccc(Cl)c1>>O=S1CCN(c2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)CC1,,ClCCl,,O,,test
US20040248854A1,COC(=O)CCCC#CCN1C(=O)CCC[C@@H]1/C=C/C(=O)Cc1ccccc1>>COC(=O)CCCC#CCN1C(=O)CCC[C@@H]1/C=C/C(O)Cc1ccccc1,,ClCCl,,CO,[BH4-].[Na+],test
US20130143892A1,CCN(C(C)C)C(C)C.CS(=O)(=O)c1ccc(-c2ccc(C(=O)N(C3CCNCC3)C3CC3)cn2)cc1>>CS(=O)(=O)c1ccc(-c2ccc(C(=O)N(C3CC3)C3CCN(C#N)CC3)cn2)cc1,,C1CCOC1,ClCCl,CCOC(C)=O,O,test
US20090286778A1,CC(C)(C)OC(=O)Nc1ccnc(/C=C\c2cccc(N)c2)c1.Clc1ncc(Cl)c(Cl)n1>>CC(C)(C)OC(=O)Nc1ccnc(/C=C\c2cccc(Nc3nc(Cl)ncc3Cl)c2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05686486,CCOC(=O)c1ccccc1O.O=C(O)CCCCc1ccccc1>>CCOC(=O)C1C=CC=CC1(O)C(=O)CCCCc1ccccc1,,ClCCl,,CC(C)N=C=NC(C)C,,test
US20060173002A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)c1ccccc1Oc1ncccc1Nc1nc(C(F)(F)F)c(Br)s1>>CC(C)(C)OC(=O)N(c1nc(C(F)(F)F)c(Br)s1)c1cccnc1Oc1ccccc1C(C)(C)C,CN(C)c1ccncc1,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20020151715A1,N.O=C(O)c1cn(-c2ccc(Cl)c(Cl)c2)cn1>>NC(=O)c1cn(-c2ccc(Cl)c(Cl)c2)cn1,,CN(C)C=O,,O,O=C(n1ccnc1)n1ccnc1,test
US20080085910A1,CC(C)I.Ic1ccc(Nc2ncccn2)cc1>>CC(C)N(c1ccc(I)cc1)c1ncccn1,,CN(C)C=O,,O,[H-].[Na+],test
US20030199573A1,CCOC(=O)C(Cc1ccccc1)Cc1c(O)c2ccccc2oc1=O>>O=C(O)C(Cc1ccccc1)Cc1c(O)c2ccccc2oc1=O,,CCO,,[Na+].[OH-],,test
US20090253736A1,CC(C)(C)C#Cc1cc(Cl)ncc1NCCO>>CC(C)(C)c1cc2cc(Cl)ncc2n1CCO,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US04654362,CO.O=C(O)c1ccc2c(c1)CCC(CO)O2>>COC(=O)c1ccc2c(c1)CCC(CO)O2,O=S(=O)(O)O,,,,,test
US20120040985A1,CC(C)(C)OC(=O)NC(=N)NC(=O)OC(C)(C)C.COc1cc(C(C)(C)c2cnc(SCc3c(F)cc(CCCO)cc3F)n2-c2ccc(F)cc2)ccc1Cl>>COc1cc(C(C)(C)c2cnc(SCc3c(F)cc(CCCNC(=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)cc3F)n2-c2ccc(F)cc2)ccc1Cl,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100035898A1,CC1CC(CNc2ccccc2)CCC1N.O=C(Cl)c1cc(C(F)(F)F)ccc1Cl>>CC1CC(CNc2ccccc2)CCC1NC(=O)c1cc(C(F)(F)F)ccc1Cl,,C1CCOC1,,,,test
US20110251194A1,NCc1cccnc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>O=C(NCc1cccnc1)Oc1ccc([N+](=O)[O-])cc1,,CCOCC,CCOCC,CCN(CC)CC,O,test
US20130184265A1,CC(Cl)OC(=O)Cl.Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1>>Cc1cc2c(s1)=Nc1ccccc1N(C(=O)OC(C)Cl)C=2N1CCN(C)CC1,,ClCCl,,CCN(CC)CC,,test
US20100261719A1,CC(=O)OCc1cc(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(N2C[C@H](C)O[C@H](C)C2)c(F)c1F>>CC(=O)OCc1cc(CO)c(N2C[C@H](C)O[C@H](C)C2)c(F)c1F,,C1COCCO1,,Cl,O,test
US20150126485A1,NCCC(O)C(=O)O.O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(Cl)c(-c2ccn[nH]2)c1>>O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(NCCC(O)C(=O)O)c(-c2ccn[nH]2)c1,,CN1CCCC1=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20070208033A1,CCCN(CCC)CCCc1cc2cc(CNCc3ncc[nH]3)ccc2s1.Cn1ccnc1C=O>>CCCN(CCC)CCCc1cc2cc(CN(Cc3ncc[nH]3)Cc3nccn3C)ccc2s1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20150376179A1,CCOC(=O)N1CCCC(N2CCC(c3cccnc3OC)CC2)CC1>>CCOC(=O)N1CCCC(N2CCC(c3cccnc3O)CC2)CC1,,C1COCCO1,,Cl,,test
US20070142441A1,CCOC(=O)c1cnn(-c2ccc(Br)cc2)c1NS(=O)(=O)C(C)C>>CC(C)S(=O)(=O)Nc1c(C(=O)O)cnn1-c1ccc(Br)cc1,,CCO,,[Na+].[OH-],,test
US20090306066A1,CN1CCNCC1.Fc1c(Cl)nc(Cl)nc1Cl.NN>>CN1CCN(c2nc(Cl)nc(NN)c2F)CC1,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US20070112015A1,CC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1c[nH]c2ccccc12>>CC(=O)C=Cc1c[nH]c2ccccc12,,CCOCC,,,,test
US20070197558A1,COc1ccc(C=Cc2ccc(C)cc2[N+](=O)[O-])cc1>>COc1ccc(CCc2ccc(C)cc2N)cc1,[Pd],CCO,,[H][H],,test
US20090270361A1,CCOC(=O)C(=O)CC(C)=O.CNOC>>CCOC(=O)/C(CC(C)=O)=N\OC,,CCO,O,Cl,,test
US20020173664A1,CC(C)[C@@H]1NC(=O)OC1=O.O=C(Cl)c1ccccc1>>CC(C)[C@H]1C(=O)OC(=O)N1C(=O)c1ccccc1,CN(C)c1ccncc1,CCOC(C)=O,,,,test
US20130030177A1,COC(=O)c1cnc(Cl)s1.Cc1nc(N)cc(Br)n1>>COC(=O)c1cnc(Nc2cc(Br)nc(C)n2)s1,,C1CCOC1,,Cl,[H-].[Na+],test
US20100324068A1,COC(=O)Cc1ccc(O)c(C(F)(F)F)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)Cc1ccc(OS(=O)(=O)C(F)(F)F)c(C(F)(F)F)c1,,ClCCl,,CCN(CC)CC,,test
US04820712,COC(=O)[C@H](C)NC(=O)OC(C)(C)C>>C[C@@H](CO)NC(=O)OC(C)(C)C,,COCCOC,,[BH4-].[Li+],,test
US06071899,CSC1CC(=O)N1.O=C(CBr)CCc1ccccc1>>CSC1CC(=O)N1CC(=O)CCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20070287724A1,CCOCC(=O)Cl.Cc1nc(Cl)c(N)c(NCC2(O)CCOCC2)c1C>>CCOCC(=O)Nc1c(Cl)nc(C)c(C)c1NCC1(O)CCOCC1,,ClCCl,,,,test
US20060264460A1,CCOC=C(C#N)C(=O)OCC.Nc1ccc([N+](=O)[O-])cc1F>>CCOC(=O)C(C#N)=CNc1ccc([N+](=O)[O-])cc1F,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US03985710,C/C=C/C=O.CCCCCCCCCCCCS>>CCCCCCCCCCCCSC(C=O)CC,,CCOCC,,,,test
US20100123388A1,CC(=O)c1ccc(Br)cc1.II.c1ccncc1>>O=C(C[n+]1ccccc1)c1ccc(Br)cc1.[I-],,O,,,,test
US20060097226A1,CCCc1ccc(-c2ccc(C=CC3(F)C(F)=C(OCC)C=CC3C)cc2)cc1>>CCCc1ccc(-c2ccc(CCC3(F)C(F)=C(OCC)C=CC3C)cc2)cc1,[Pd],Cc1ccccc1,,[H][H],,test
US20070191447A1,CN(C(=O)Cn1c(=O)oc2ccc(Br)cc21)c1ccccc1.Oc1ccccc1>>CN(C(=O)Cn1c(=O)oc2ccc(Oc3ccccc3)cc21)c1ccccc1,O=[Cu],ClC(Cl)Cl,c1ccncc1,O=C([O-])[O-].[K+].[K+],,test
US20150152047A1,COc1cc(Cl)ccc1Cl.O=[N+]([O-])O>>COc1cc(Cl)c([N+](=O)[O-])cc1Cl,,O,,O=S(=O)(O)O,,test
US20130131039A1,O=C1CC2(CCCCC2)C1(Cl)Cl>>O=C1CC2(CCCCC2)C1,[Zn],CC(=O)O,,O,,test
US05426226,CCCC(=O)c1cccc2c1CC(N(CCC)CCC)CC2.NO>>CCCC(=NO)c1cccc2c1CC(N(CCC)CCC)CC2,,CO,O,Cl,[NH4+].[OH-],test
US05861407,CS(=O)(=O)Cl.Cc1ccc(S(=O)(=O)Cl)cc1.OCc1c[nH]cn1>>Cc1ccc(S(=O)(=O)n2cnc(COS(C)(=O)=O)c2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US05493020,CCOC(=O)CCNC(=O)c1cc(OCc2ccc(C#N)cc2)ccc1N.O=C(Br)CBr>>CCOC(=O)CCNC(=O)c1cc(OCc2ccc(C#N)cc2)ccc1NC(=O)CBr,,ClCCl,O,,,test
US09181234B2,CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(CC)(C(=O)OCC)CC4)nc3)cc(C(=O)CC)c2s1>>CCNC(=O)Nc1nc2cc(-c3cnc(N4CCC(CC)(C(=O)O)CC4)nc3)cc(C(=O)CC)c2s1,,CCO,,[Na+].[OH-],,test
US20090197863A1,COC(=O)c1cccc(N)c1O.Cc1cccc(C(=O)Cl)c1>>COC(=O)c1cccc(NC(=O)c2cccc(C)c2)c1O,,Cc1ccccc1,,c1ccncc1,,test
US20050197328A1,CCn1c(-c2nonc2N)nc2cncc(Br)c21.O=C(O)c1ccc(B(O)O)cc1>>CCn1c(-c2nonc2N)nc2cncc(-c3ccc(C(=O)O)cc3)c21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20150148332A1,Cc1nc2cc(Cl)ccc2[nH]c1=O.Cc1nc2ccc(Cl)cc2[nH]c1=O.O=P(Br)(Br)Br>>Cc1nc2cc(Cl)ccc2nc1Br.Cc1nc2ccc(Cl)cc2nc1Br,CN(C)C=O,,,[NH4+].[OH-],,test
US20120107307A1,Cc1cc(C(=O)O)c(Nc2ccc(I)cc2F)n(C)c1=O.O=C1CCC(=O)N1O>>Cc1cc(C(=O)ON2C(=O)CCC2=O)c(Nc2ccc(I)cc2F)n(C)c1=O,,C1COCCO1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US06927214B1,Cc1nc2cc(F)c(F)cc2[nH]c1=O.O=P(Cl)(Cl)Cl>>Cc1nc2cc(F)c(F)cc2nc1Cl,CN(C)c1ccncc1,,,,,test
US20090163508A1,Fc1ccc(-c2cc(N3CCNCC3)ncn2)cc1.O=C(Nc1cccnn1)OCC(Cl)(Cl)Cl>>O=C(Nc1cccnn1)N1CCN(c2cc(-c3ccc(F)cc3)ncn2)CC1,,C1CCOC1,CCCCCC,,,test
US20100075952A1,Cc1c(C=O)[nH]c2c1C(=O)N(CC(O)CN1CCOCC1)CCC2.Cc1cccc2c1CC(=O)N2>>Cc1cccc2c1/C(=C/c1[nH]c3c(c1C)C(=O)N(C[C@H](O)CN1CCOCC1)CCC3)C(=O)N2,,CCO,,C1CCNCC1,,test
US04957927,COc1ccccc1C1CCCN(C(=O)COC(c2ccccc2)c2ccccc2)C1.O=C(O)C(=O)O>>COc1cccc(C2CCCN(CCOC(c3ccccc3)c3ccccc3)C2)c1.O=C(O)C(=O)O,,C1CCOC1,CC(C)=O,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20060205718A1,CC(C)(C)[Si](C)(C)Cl.OCc1ccc(F)cc1>>CC(C)(C)[Si](C)(C)OCc1ccc(F)cc1,,CN(C)C=O,,c1c[nH]cn1,,test
US20090137601A1,COC(=O)[C@@H](N)Cc1ccc(C2=CCNCC2)cc1.O=C(Cl)c1ccc(F)cc1>>COC(=O)[C@@H](N)Cc1ccc(C2=CCN(C(=O)c3ccc(F)cc3)CC2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120071461A1,Cc1cc(N2CCC(N(C)C(=O)OCc3ccccc3)CC2)nc(C)n1>>CNC1CCN(c2cc(C)nc(C)n2)CC1,,CO,,,,test
US20040053913A1,OCc1cc2n(n1)CCCC2>>O=Cc1cc2n(n1)CCCC2,O=[Mn]=O,ClC(Cl)Cl,,,,test
US20110166139A1,COCc1nn(C)cc1[N+](=O)[O-]>>COCc1nn(C)cc1N,[Pd],CO,,CCOC(C)=O,,test
US04933355,OCc1csc(Nc2ccc(F)cc2)n1>>O=Cc1csc(Nc2ccc(F)cc2)n1,,CS(C)=O,,CCN(CC)CC,,test
US05273991,CN(C)NC(=O)c1nc(NC(=O)c2nc([N+](=O)[O-])cn2C)cn1C>>CN(C)NC(=O)c1nc(NC(=O)c2nc(N)cn2C)cn1C,[Pd],CO,,,,test
US20160016948A1,Brc1cc2[nH]ccc2cn1.CCC(C)Br>>CCC(C)n1ccc2cnc(Br)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20110245257A1,CNC(=O)c1cccc(NC(=O)[C@H](C)NC(=O)OC(C)(C)C)c1NC1CC1>>CNC(=O)c1cccc2nc([C@H](C)N)n(C3CC3)c12,,CC(=O)O,,,,test
US20120088752A1,CCOC(=O)C1CCN(c2ccc(Cl)c(-c3nc4cc(F)ccc4n3C(=O)OC(C)(C)C)c2)CC1.Cl>>Cl.O=C(O)C1CCN(c2ccc(Cl)c(-c3nc4cc(F)ccc4[nH]3)c2)CC1,,Cl,,,,test
US20040248923A1,C=Cc1c(C(=O)OC)cccc1[N+](=O)[O-]>>CCc1c(N)cccc1C(=O)OC,[Pd],CCO,CCOC(C)=O,,,test
US20070244117A1,COc1ccc(CN)cc1.N#Cc1cccnc1Cl>>COc1ccc(CNc2ncccc2C#N)cc1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20070142434A1,CC(C)(C)OC(=O)N1CCC[C@@H]1COc1ccc(N2C(=O)c3ccccc3C2=O)cc1.Cl>>Cl.O=C1c2ccccc2C(=O)N1c1ccc(OC[C@H]2CCCN2)cc1,,C1COCCO1,,,,test
US20100311966A1,CCOC(=O)c1nc(N2CC[C@H](NC(=O)c3nc(C(F)(F)F)c(CC)[nH]3)[C@H](OC)C2)sc1C>>CCc1[nH]c(C(=O)N[C@H]2CCN(c3nc(C(=O)O)c(C)s3)C[C@H]2OC)nc1C(F)(F)F,,CO,,[Na+].[OH-],,test
US04439440,CC(C)OC(=O)c1ccc(N=C=O)cc1.N#CCCCC1CNN=C1c1ccc(Cl)cc1>>CC(C)OC(=O)c1ccc(NC(=O)N2CC(CCCC#N)C(c3ccc(Cl)cc3)=N2)cc1,,CCOCC,,,,test
US20100222352A1,CC(C)=CCBr.COc1ccc(Nc2nc(C)cs2)cc1O>>COc1ccc(Nc2nc(C)cs2)cc1OCC=C(C)C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05212187,CN(CCCN)CCC(c1ccc(Cl)cc1)c1ccccn1.Cc1[nH]cnc1CSCCN.O=C(n1ccnc1)n1ccnc1>>Cc1[nH]cnc1CSCCNC(=O)NCCCN(C)CCC(c1ccc(Cl)cc1)c1ccccn1,,CCOC(C)=O,CO,,,test
US20150152047A1,CC(C)(C)OC(=O)N1CCC[C@H](CCC(=O)O)C1.OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@H](CCNC(=O)OCc2ccccc2)C1,,Cc1ccccc1,,CCN(CC)CC,,test
US20130225569A1,Clc1ccnc2cc(-c3ccccc3)oc12.Nc1ccc(O)cc1>>Nc1ccc(Oc2ccnc3cc(-c4ccccc4)oc23)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20060293353A1,COc1ccc(COC(CCc2ccc(-c3ccccc3)cc2)C(CCO[Si](C)(C)C(C)(C)C)C(=O)OC(C)(C)C)cc1>>COc1ccc(COC(CCc2ccc(-c3ccccc3)cc2)C(CCO)C(=O)OC(C)(C)C)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20060281799A1,CC(C)(C)[Si](C)(C)OC1CCc2cccc(NC(N)=S)c2C1.COC(OC)C(Br)c1ccccc1>>OC1CCc2cccc(Nc3ncc(-c4ccccc4)s3)c2C1,,CCO,Cl,,,test
US06150373,COc1ccc(COc2nc(SC)ncc2CNc2ccc(Cl)cc2Cl)cc1>>CSc1ncc(CNc2ccc(Cl)cc2Cl)c(=O)[nH]1,,O=C(O)C(F)(F)F,,,,test
US20100331385A1,CC(=O)OC(C)=O.CC(C)CCON=O.Cc1cc(Oc2ccc(F)cc2C#N)ccc1N>>CC(=O)n1ncc2cc(Oc3ccc(F)cc3C#N)ccc21,,Cc1ccccc1,,CC(=O)[O-].[K+],,test
US05576334,CC(C)(C)OC(=O)[C@@H](N)Cc1ccc([N+](=O)[O-])cc1.CCCCS(=O)(=O)Cl>>CCCCS(=O)(=O)N[C@@H](Cc1ccc([N+](=O)[O-])cc1)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20040254175A1,Cc1cc(NC(=O)C(Nc2cccc(C#N)c2)c2ccccc2)ccc1N1CCCS1(=O)=O>>Cc1cc(NC(=O)C(Nc2cccc(CN)c2)c2ccccc2)ccc1N1CCCS1(=O)=O,,CO,,N,O,test
US20070299092A1,COCCOc1cc2ncc(C#N)c(Cl)c2cc1OC.Cc1ccc(N)cc1O>>COCCOc1cc2ncc(C#N)c(Nc3ccc(C)c(O)c3)c2cc1OC,,CC(C)O,,Cl,c1ccncc1,test
US05616599,CCCCc1nc(C(O)C(C)C)c(C#N)n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCCCc1nc(C(O)C(C)C)c(C#N)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1,,CC(=O)O,,,,test
US20110053940A1,COCCCc1ccc(SC)c(C(=O)OC)c1>>COCCCc1ccc(SC)c(CO)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20050014840A1,COc1ccc(S(=O)(=O)Cl)cc1.NCCO>>COc1ccc(S(=O)(=O)NCCO)cc1,,C1CCOC1,O,CCN(CC)CC,,test
US05244908,O=C(NCCSc1cccc2nccn12)c1ccccc1O.O=C(n1ccnc1)n1ccnc1>>O=c1oc2ccccc2c(=O)n1CCSc1cccc2nccn12,,C1CCOC1,,,,test
US20050014788A1,C[C@@H]1[C@H](c2ccccc2)N(C(=O)C[C@@H](c2ccccc2)c2ccc(S(C)(=O)=O)cc2)C(=O)N1C>>CS(=O)(=O)c1ccc([C@@H](CCO)c2ccccc2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130030012A1,O=C(O)Cc1ccc(O)c(F)c1>>OCCc1ccc(O)c(F)c1,,C1CCOC1,,B,CO,test
US20150065519A1,NC(=S)c1ccnc(CC2CCCCC2)c1.O=C(CBr)c1ccc(NS(=O)(=O)C(F)(F)F)cc1Cl>>O=S(=O)(Nc1ccc(-c2csc(-c3ccnc(CC4CCCCC4)c3)n2)c(Cl)c1)C(F)(F)F,,CCO,,,,test
US20100222318A1,CN(Cc1ccc(-c2cc(-c3nc(-c4ccc(S(=O)(=O)C5CCOC5)cc4)cnc3N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)on2)c(F)c1)C(=O)OC(C)(C)C>>CNCc1ccc(-c2cc(-c3nc(-c4ccc(S(=O)(=O)C5CCOC5)cc4)cnc3N)on2)c(F)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130345215A1,COCCOc1cc(F)c(C2(O)CCN(C(=O)OC(C)(C)C)CC2)c(F)c1.Cl>>COCCOc1cc(F)c(C2(O)CCNCC2)c(F)c1.Cl,,CCOC(C)=O,,,,test
US05583261,C=C(C)C(=C)C.O=C1C=CC(=O)O1>>CC1=C(C)C[C@@H]2C(=O)OC(=O)[C@@H]2C1,,Cc1ccccc1,,,,test
US05532236,CCOC(=O)C(=O)Cl.Cc1nccn1-c1cc(N)c([N+](=O)[O-])cc1C(F)(F)F>>CCOC(=O)C(=O)Nc1cc(-n2ccnc2C)c(C(F)(F)F)cc1[N+](=O)[O-],,c1ccncc1,,,,test
US20070191604A1,Brc1ccc(-c2ncccn2)cn1.CC(C)(C)OC(=O)N1CC=C(B(O)O)CC1>>CC(C)(C)OC(=O)N1CC=C(c2ccc(-c3ncccn3)cn2)CC1,,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060235033A1,COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.COc1cccc([C@H](C)N)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cccc([C@H](C)NC(=O)Nc2ccc(Oc3ccnc4cc(OC)c(OC)cc34)cc2)c1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20090156607A1,Clc1cc(Cl)n2nc(C3CC3)cc2n1>>Clc1ccn2nc(C3CC3)cc2n1,[Zn],CC(=O)O,,,,test
US06399616B1,CCOC(=O)Cl.c1ccc(CN2CCC(c3nccc4sccc34)CC2)cc1>>CCOC(=O)N1CCC(c2nccc3sccc23)CC1,,Cc1ccccc1,O,O=C([O-])[O-].[K+].[K+],,test
US20050130989A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.Cc1cc(C(=O)N2CCN(c3cccc(Cl)c3)CC2)n(-c2ccccc2)n1>>Cc1cc(C(=S)N2CCN(c3cccc(Cl)c3)CC2)n(-c2ccccc2)n1,,Cc1ccccc1,,CCOC(C)=O,,test
US04766131,CC(=O)Oc1ccc(CC(=O)Cl)cc1.COc1cc2c(cc1OC)C(C)NCC2>>COc1cc2c(cc1OC)C(C)N(C(=O)Cc1ccc(OC(C)=O)cc1)CC2,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20060293499A1,O=C(OCc1ccccc1)c1ccc2c(c1)Cc1cc(C(=O)OCc3ccccc3)ccc1-2.O=COCc1ccccc1>>O=CC1c2cc(C(=O)OCc3ccccc3)ccc2-c2ccc(C(=O)OCc3ccccc3)cc21,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20150119393A1,CCOC(=O)Cl.NC1CCN(c2ccc(Br)cc2)CC1>>CCOC(=O)NC1CCN(c2ccc(Br)cc2)CC1,,ClCCl,,CCN(CC)CC,,test
US04914204,Fc1c(F)c(F)c(F)c(F)c1F.OC1(c2ccccc2)CCN(Cc2ccccc2)CC1>>Fc1c(F)c(F)c(OC2(c3ccccc3)CCN(Cc3ccccc3)CC2)c(F)c1F,,CN(C)C=O,,O,[H-].[Na+],test
US20060047001A1,NCc1csc2ccc(Cl)cc12.NS(N)(=O)=O>>NS(=O)(=O)NCc1csc2ccc(Cl)cc12,,C1COCCO1,O,,,test
US20090029958A1,COC1(CN=[N+]=[N-])CCN(CCOCCc2ccccc2)CC1>>COC1(CN)CCN(CCOCCc2ccccc2)CC1,[Pd],CCO,,[H][H],,test
US20120238751A1,CN.Clc1ncc(OCc2ccccc2)cn1>>CNc1ncc(OCc2ccccc2)cn1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20140256767A1,O=C1c2ccccc2C(=O)N1CC1=NCCc2ccccc21>>O=C1c2ccccc2C(=O)N1CC1NCCc2ccccc21,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20100210591A1,CCOC(=O)C=Cc1ccc(NC(=S)c2cc([Si](C)(C)C)cc([Si](C)(C)C)c2)cc1>>C[Si](C)(C)c1cc(C(=S)Nc2ccc(C=CC(=O)O)cc2)cc([Si](C)(C)C)c1,,CCO,,Cl,[Na+].[OH-],test
US05753679,Cc1ccc(C(=O)Cl)cc1.O=[N+]([O-])c1ccccc1CN1CCC(O)CC1>>Cc1ccc(C(=O)OC2CCN(Cc3ccccc3[N+](=O)[O-])CC2)cc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20100278833A1,COC(=O)C1(Cl)SC=CC1=O.COc1cc2[nH]cnc2cn1>>COC(=O)c1sc(-n2cnc3cc(OC)ncc32)cc1O,,ClC(Cl)Cl,,,,test
US20130267508A1,Nc1cc(Cl)ccc1NCCCn1ccnc1.O=C(O)CO>>OCc1nc2cc(Cl)ccc2n1CCCn1ccnc1,,Cl,O,ClCCl,O=C([O-])O.[Na+],test
US20010046975A1,C=O.CCNC(=O)c1cc(N)ccc1[Si](C)(C)C.c1ccc2[nH]nnc2c1>>CCNC(=O)c1cc(NCn2nnc3ccccc32)ccc1[Si](C)(C)C,,CCO,,,,test
US20100179150A1,COC(=O)c1sc(N2CC[C@H](NC(=O)c3cc(Cl)c(C)[nH]3)[C@H](OC)C2)nc1C(=O)NC(C)(C)c1ccccc1>>COC(=O)c1sc(N2CC[C@H](NC(=O)c3cc(Cl)c(C)[nH]3)[C@H](OC)C2)nc1C(N)=O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20090215778A1,CC(=O)c1ccn(C)n1>>C[C@@H](O)c1ccn(C)n1,,CCOC(C)=O,,CO,,test
US20030195221A1,CSc1nc(-c2ccncc2)c(-c2ccc3ccccc3c2)c2nncn12.c1ccc(C[C@H]2CNCCN2)cc1>>c1ccc(C[C@H]2CN(c3nc(-c4ccncc4)c(-c4ccc5ccccc5c4)c4nncn34)CCN2)cc1,,CN(C)C=O,,,,test
US05102880,CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2[N+](=O)[O-])cc1>>CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2N)cc1,[Pd],CCO,,[H][H],,test
US20070244095A1,Cc1cc2c(cc1C(F)(F)F)N(CC1CC1)CCC[C@@H]2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(CCN)n1.Cl>>Cc1cc2c(cc1C(F)(F)F)N(CC1CC1)CCC[C@@H]2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(CCN)n1.Cl,,CCOCC,,,,test
US20140309417A1,CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C[C@@H]4OC45C[C@@H](O)CC[C@]5(C)[C@H]3CC[C@]12C.NCCO>>CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C[C@@H](NCCO)[C@@]4(O)C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,,COC(C)(C)C,,CCCCO,,test
US20020019427A1,CC(C)(C)OC(=O)NC1=NC(CO)CS1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)CC2CSC(NC(=O)OC(C)(C)C)=N2)cc1,,ClCCl,,CCN(CC)CC,,test
US20040152697A1,C[C@@H](C(=O)OC(C)(C)C)N1CC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O.O=C(CBr)OCc1ccccc1>>C[C@@H](C(=O)OC(C)(C)C)N1CC[C@H](N(CC(=O)OCc2ccccc2)S(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140142082A1,Cc1c(S(=O)(=O)NC2CC2)cc(C(=O)O)n1CC1CCCCC1>>Cc1c(S(=O)(=O)NC2CC2)ccn1CC1CCCCC1,,CCO,,Cl,,test
US20140045746A1,CS(=O)(=O)OC1CC(C#N)C1.Cc1cc(C)cc(O)c1>>Cc1cc(C)cc(OC2CC(C#N)C2)c1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070190359A1,CC(C)c1ccc(N)c(Br)c1.N#Cc1ccccc1B1OCCCO1>>CC(C)c1ccc2nc(N)c3ccccc3c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20160024060A1,CC(=O)c1ccc(C(C)=O)c2c(C)c(C(=O)Nc3cc(C(C)(C)O)c4ccccc4n3)sc12.Cl>>CC(=O)c1ccc(C(C)=O)c2c(C)c(C(=O)Nc3cc(C(C)(C)O)c4ccccc4n3)sc12.Cl,,CC(C)O,,,,test
US20150087663A1,CC(=O)CN.O=C(Cl)c1c(Cl)ncnc1Cl>>CC(=O)CNC(=O)c1c(Cl)ncnc1Cl,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20090318405A1,CCS(=O)(=O)Cl.N#CCC1(n2cc(-c3ccnc(Cl)n3)cn2)CNC1>>CCS(=O)(=O)N1CC(CC#N)(n2cc(-c3ccnc(Cl)n3)cn2)C1,,ClCCl,,CCN(CC)CC,Cl,test
US20150152077A1,COc1ccc2c(c1)Oc1cc(OC)ccc1C2=C1CCCC1>>Oc1ccc2c(c1)Oc1cc(O)ccc1C2C1CCCC1,,ClCCl,,BrB(Br)Br,,test
US20050197362A1,COc1ccccc1CCN(CCCCC(=O)c1ccc2c(c1)CCN2C(C)=O)C(=O)OC(C)(C)C>>COc1ccccc1CCN(CCCCC(=O)c1ccc2c(c1)CCN2)C(=O)OC(C)(C)C,,CO,,[K+].[OH-],,test
US07947693B2,CC(C)C[C@H](N)CO.C[C@H](Sc1nc(Cl)c2sc(N)nc2n1)c1ccccc1>>CC(C)CC(CO)Nc1nc(S[C@@H](C)c2ccccc2)nc2nc(N)sc12,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,O,test
US20100261709A1,CC(C)(C)OC(=O)NC1CCC(O)C1.COCCN(CCOC)S(F)(F)F>>CC(C)(C)OC(=O)N[C@H]1CC[C@@H](F)C1,,ClCCl,,,,test
US20020035121A1,ClCc1ccccn1.Oc1cc(-c2ccc(F)cc2)nc2ccsc12>>Fc1ccc(-c2cc(OCc3ccccn3)c3sccc3n2)cc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20070191583A1,CCCCCCCCCCc1ccc(C(=O)c2cc(Cl)ccc2I)cc1.CCCCCCCCCCc1ccc(C(=O)c2ccccc2B2OC(C)(C)C(C)(C)O2)cc1>>CCCCCCCCCCc1ccc(C(=O)c2ccccc2-c2ccc(Cl)cc2C(=O)c2ccc(CCCCCCCCCC)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20130225548A1,O=S(Cl)Cl.OCc1cncc(Br)c1>>Cl.ClCc1cncc(Br)c1,,CCOCC,,,,test
US20090105259A1,N[C@@H](CC(Cl)Cl)C(=O)O.O=C(ON1C(=O)CCC1=O)c1cc2ccccc2s1>>O=C(N[C@@H](CC(Cl)Cl)C(=O)O)c1cc2ccccc2s1,,CCO,ClCCl,CCN(CC)CC,O,test
US20050182040A1,CC(C)(C)OC(=O)NC1CCC(C(=O)Nc2ccc(C(N)=O)cc2)CC1>>NC(=O)c1ccc(NC(=O)C2CCC(N)CC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20040106604A1,CCOC(=O)c1n[nH]c(-c2ccccn2)c1-c1ccnc2ccccc12.OCCBr>>O=C1OCCn2nc(-c3ccccn3)c(-c3ccnc4ccccc34)c21,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20150051238A1,CC(=O)NN.Cc1nn(C(C)(C)C(=O)O)cc1[N+](=O)[O-]>>CC(=O)NNC(=O)C(C)(C)n1cc([N+](=O)[O-])c(C)n1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20010027196A1,CN1CCNCC1.CS(=O)(=O)c1nc(N)nc(-c2ccco2)c1C#N>>CN1CCN(c2nc(N)nc(-c3ccco3)c2C#N)CC1,,COCCOC,,,,test
US06255517B1,CC(=O)OC(C)=O.CC(C)(O)c1ccc(O)cc1O>>C=C(C)c1ccc(OC(C)=O)cc1OC(C)=O,,CC(=O)OC(C)=O,,,,test
US20050171180A1,CCC(CC)C(N=[N+]=[N-])c1ccnn1S(=O)(=O)c1ccc(C)cc1>>CCC(CC)C(N)c1ccnn1S(=O)(=O)c1ccc(C)cc1,[Pd],,,,,test
US20130143826A1,CC(C)(C)OC(=O)N[C@H](CCC(=O)OCc1ccccc1)C(=O)O.O=C1CCC(=O)N1O>>CC(C)(C)OC(=O)N[C@H](CCC(=O)OCc1ccccc1)C(N)=O,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US04956175,NCCS.O=C1CCCCCO1>>O=C(CCCCCO)NCCS,[Zn],O,,,,test
US20120157453A1,CCCS(=O)(=O)N(C)c1ccc(F)c(NC(=O)Oc2ccccc2)c1F.COc1n[nH]c2ncnc(N)c12>>CCCS(=O)(=O)N(C)c1ccc(F)c(NC(=O)Nc2ncnc3[nH]nc(OC)c23)c1F,,C1CCOC1,,CCN(CC)CC,O,test
US20100063120A1,COc1ccc([C@@]2(C)NC(=O)N(c3ccc(C#N)c(C(F)(F)F)c3)C2=O)cc1>>C[C@]1(c2ccc(O)cc2)NC(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C1=O,,ClCCl,,O=C([O-])O.[Na+],,test
US20110136789A1,CCC(N)Cc1cccs1.CCOC(=O)C=O.CCOC(=O)Cl>>CCOC(=O)CN(C(=O)OCC)C(CC)Cc1cccs1,CC(=O)O,CC(=O)O,ClCCl,O=C([O-])O.[Na+],,test
US04902332,C#Cc1ccc(Cl)cc1.CC(C)C(=O)c1cncnc1>>CC(C)C(O)(C#Cc1ccc(Cl)cc1)c1cncnc1,,C1CCOC1,O,[Li]CCCC,[Cl-].[NH4+],test
US20110065702A1,CC(C)(C)OC(=O)Nc1ccc2c(c1)/C(=C\c1ccc3cn[nH]c3c1)C(=O)N2.O=C(O)C(F)(F)F>>O=C([O-])C(F)(F)F.[NH3+]c1ccc2c(c1)/C(=C\c1ccc3cn[nH]c3c1)C(=O)N2,,ClCCl,,,,test
US20120277207A1,CC(Cl)OC(=O)Cl.c1ccc(C(c2ccccc2)N2CC(Oc3cccc4ccoc34)C2)cc1>>Cl.c1cc(OC2CNC2)c2occc2c1,,ClCCl,,CCO,,test
US20080015146A1,COC(=N)[C@@H]1CCCN1C(=O)OC(C)(C)C.NNc1ccccc1.c1ccncc1>>CC(C)(C)OC(=O)N1CCC[C@H]1c1ncn(-c2ccccc2)n1,,CO,,CCN(CC)CC,,test
US20080015187A1,CCOC(=O)C(O)CNC(=O)OC(C)(C)C.CS(=O)(=O)OS(C)(=O)=O>>CCOC(=O)C(CNC(=O)OC(C)(C)C)OS(C)(=O)=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110212937A1,C1CC2OC2C1.Fc1cc(Br)cc(F)c1F>>O[C@H]1CCC[C@@H]1c1cc(F)c(F)c(F)c1,[Cu]I,C1CCOC1,,[Mg],,test
US04749713,N#Cc1ccc(CCl)cc1.c1c[nH]cn1>>N#Cc1ccc(Cc2ncc[nH]2)cc1,,CC(C)=O,CCOCC,[I-].[K+],,test
US04379167,OC(Cl)CCCCl.Oc1ccccc1>>OC(CCCl)COc1ccccc1,,O,,[Na+].[OH-],,test
US20140142082A1,Cn1c(C(=O)C2CCCCC2)ccc1S(=O)(=O)Cl.N>>Cn1c(C(=O)C2CCCCC2)ccc1S(N)(=O)=O,,ClCCl,,Cl,,test
US04640707,C#CCN1C(=O)COc2cc(F)c(N)cc21.O=C1OC(=O)C2=C1CCCC2>>C#CCN1C(=O)COc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc21,,O,,CC(=O)O,,test
US20080132480A1,O=S(=O)(Cl)c1ccc(Br)cc1F>>Fc1cc(Br)ccc1S,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060089344A1,O=C1c2ccccc2C(=O)N1CCBr.c1ccc2c(N3CCNCC3)cccc2c1>>O=C1c2ccccc2C(=O)N1CCN1CCN(c2cccc3ccccc23)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020032340A1,CCC(CC)[C@H](O)CS[C@@H](C)C1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>CCC(CC)[C@H](O)CS[C@@H](C)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080153852A1,COc1ccc(Br)c(C(O)C(F)(F)F)c1.Cc1cn[nH]c1>>COc1ccc(-n2cc(C)cn2)c(C(O)C(F)(F)F)c1,[Cu]I,CCOC(C)=O,Cc1ccccc1,CN[C@@H]1CCCC[C@H]1NC,O=C([O-])[O-].[K+].[K+],test
US20030105074A1,C1N2CN3CN1CN(C2)C3.COc1ccc(CN2C(=O)c3ccccc3C2=O)cc1.O=C(O)C(F)(F)F>>COc1ccc(CN2C(=O)c3ccccc3C2=O)cc1C=O,,O,,O=C([O-])[O-].[K+].[K+],,test
US20130131040A1,NC(=O)c1ncc(N[C@H](C2CC2)C2(NC(=O)OCc3ccccc3)CC2)nc1Nc1cccc(-c2ncccn2)c1>>NC(=O)c1nccnc1Nc1cccc(-c2ncccn2)c1,,ClCCl,,BrB(Br)Br,,test
US20150141455A1,CC(C)(C)OC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)O.N[C@H]1C[C@@H]1c1ccccc1>>CC(C)(C)OC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)N[C@H]1C[C@@H]1c1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060183736A1,CS(=O)(=O)c1ccc(-c2sc3cc(O)ccc3c2Oc2ccc(OCCN3CCCCC3)cc2)cc1.Cl>>CS(=O)(=O)c1ccc(-c2sc3cc(O)ccc3c2Oc2ccc(OCCN3CCCCC3)cc2)cc1.Cl,,CCOC(C)=O,CCOCC,,,test
US20050209260A1,CC(=O)Cl.COc1ccc(S(=O)(=O)c2ccc(C)cc2)c(C(C)C)c1>>COc1cc(C(C)C)c(S(=O)(=O)c2ccc(C)cc2)cc1C(C)=O,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4ccc(F)cc4F)nc(Cl)c3n2)cc1.Nc1ccc(N2CCOCC2)cc1>>Fc1ccc(-c2nc(Nc3ccc(N4CCOCC4)cc3)c3[nH]ncc3n2)c(F)c1,C1COCCO1,CO,,Cl,,test
US20110098290A1,COC(=O)c1cc(C(C)C)c(O)cc1O.COCCl>>COCOc1cc(O)c(C(=O)OC)cc1C(C)C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100266504A1,CC(C)N(C)c1ccc2c(n1)[C@H](C)CN(C(=O)OC(C)(C)C)C2.Cl>>CC(C)N(C)c1ccc2c(n1)[C@H](C)CNC2.Cl,,CO,,CCOC(C)=O,,test
US05623081,C=CC[Mg]Br.O=CCOCc1ccccc1>>C=CCC(O)COCc1ccccc1,,CCOCC,CCOCC,[Cl-].[NH4+],,test
US05686424,CC[C@H](C)[C@H](N)C(=O)NCc1ccncc1.O=C(O)[C@@H]1CCCN1CC(=O)C12CC3CC(CC(C3)C1)C2>>CC[C@H](C)[C@H](N)C(=O)N(Cc1ccncc1)C(=O)[C@@H]1CCCN1CC(=O)C12CC3CC(CC(C3)C1)C2,,ClCCl,,CCN(CC)CC,,test
US20120184544A1,CI.COC(=O)c1cc(Oc2ccc(-c3nnc(C)o3)cc2)cc(O[C@H]2CCNC2=O)c1>>COC(=O)c1cc(Oc2ccc(-c3nnc(C)o3)cc2)cc(O[C@H]2CCN(C)C2=O)c1,,CN(C)C=O,,[H-].[Na+],,test
US20060052315A1,Cc1ccc(C)c(I)c1.O=Cc1ccc(B(O)O)cc1>>Cc1ccc(C)c(-c2ccc(C=O)cc2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US20130096144A1,N[C@@H](Cc1ccccc1F)C(=O)O>>N[C@H](CO)Cc1ccccc1F,,C1CCOC1,C1CCOC1,,,test
US05866568,COc1nc(C)cnc1NS(=O)(=O)c1cccnc1Cl.C[Si](C)(C)CCOCCl>>COc1nc(C)cnc1N(COCC[Si](C)(C)C)S(=O)(=O)c1cccnc1Cl,,CN(C)C=O,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US06140351,CN1CCNCC1.COC(=O)c1scc(CBr)c1Cl>>COC(=O)c1scc(CN2CCN(C)CC2)c1Cl,,ClCCl,,,,test
US20030008872A1,CCI.CS(=O)(=O)c1ccc(-c2c(-c3ccc(O)cc3)nn3ncccc23)cc1>>CCOc1ccc(-c2nn3ncccc3c2-c2ccc(S(C)(=O)=O)cc2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04657579,CCON=CC(C)Nc1c(OC)ncnc1OC.O=C(Cl)CCl>>CCON=CC(C)N(C(=O)CCl)c1c(OC)ncnc1OC,,ClCCl,,[Na+].[OH-],,test
US20120202783A1,Cc1cc(C)nc(N2C[C@@H]3CCN(C(=O)c4cc(F)ccc4Br)C[C@@H]32)n1.OB(O)c1cncnc1>>Cc1cc(C)nc(N2C[C@@H]3CCN(C(=O)c4cc(F)ccc4-c4cncnc4)C[C@@H]32)n1,,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20150104526A1,CON(C)C(=O)c1cc(NCCC(F)(F)F)c2ncc(-c3ccc(C(=O)NC4CC4)c(C)c3)n2n1.Fc1cccc([Mg]Br)c1>>Cc1cc(-c2cnc3c(NCCC(F)(F)F)cc(C(=O)c4cccc(F)c4)nn23)ccc1C(=O)NC1CC1,,C1CCOC1,,,,test
US20150119405A1,C=CC(=O)Cl.COc1cc(OC)c(Cl)c(-c2ccc3nc(N[C@H]4[C@@H](N)C[C@@H]5C[C@H]45)ncc3c2)c1Cl>>C=CC(=O)N[C@H]1C[C@@H]2C[C@@H]2[C@H]1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)ccc2n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20140080816A1,CC(Br)C(N)=O.c1ccc2c(c1)NCCN2C1CC1>>CC(C(N)=O)N1CCN(C2CC2)c2ccccc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20090270412A1,C=O.CNCCc1cn(CCC2CCCCC2)c2ccc(C)cc12>>Cc1ccc2c(c1)c1c(n2CCC2CCCCC2)CN(C)CC1,,CC#N,,O=C(O)C(F)(F)F,,test
US20050171153A1,CCOC(=O)C=O.Cc1cc(F)ccc1N>>CCOC(=O)CNc1ccc(F)cc1C,,Cc1ccccc1,,,,test
US20100063081A1,COC(=O)c1ccc(/C=C/CCC2CCN(C(=O)OC(C)(C)C)CC2)cc1>>COC(=O)c1ccc(CCCCC2CCN(C(=O)OC(C)(C)C)CC2)cc1,[Pd],CCO,CCOC(C)=O,,,test
US20060004021A1,CC(OS(C)(=O)=O)c1nnn(-c2cc(Cl)ccc2F)n1.CCOC(=O)N1CCNCC1>>CCOC(=O)N1CCN(C(C)c2nnn(-c3cc(Cl)ccc3F)n2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120245345A1,COC(=O)c1c(O)cnc2ccc(OC)cc12>>COc1ccc2ncc(O)c(CO)c2c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120171245A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC12CCC(I)C(C1)NC2=O>>CC(C)(C)OC(=O)N1C(=O)C2(C)CCC(I)C1C2,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20100305133A1,CCOC(=O)CNC(=O)c1c(O)c(-c2ncc(C)s2)cc2nccnc12>>Cc1cnc(-c2cc3nccnc3c(C(=O)NCC(=O)O)c2O)s1,,CCO,,[Na+].[OH-],,test
US05026856,Nc1c(F)c(F)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1.Nc1ccc2c(c1)CNC2>>Nc1ccc2c(c1)CN(c1c(F)c(N)c3c(=O)c(C(=O)O)cn(C4CC4)c3c1F)C2,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20090281140A1,CCOC(=O)C(=O)CBr.NC(=S)C1CCCCC1>>CCOC(=O)c1csc(C2CCCCC2)n1,,C1CCOC1,,,,test
US20100137322A1,COC(=O)c1ccc(C(=O)N(C)CC(F)(F)F)nc1>>CN(CC(F)(F)F)C(=O)c1ccc(C(=O)O)cn1,,C1CCOC1,O,[Li+].[OH-],,test
US04097587,CCC1(C)CC2(NC(=O)N(C)C2=O)C(C)C(C)(CC)N1C.CI>>CCC1(C)CC2(C(=O)N(C)C(=O)N2C)C(C)C(C)(CC)N1C,,CN(C)C=O,,[H-].[Na+],O=C([O-])[O-].[K+].[K+],test
US20140275030A1,Cc1noc(C)c1-c1ccc2nc(Cl)n3c2c1OCC3c1cccnc1.OC1CNC1>>Cc1noc(C)c1-c1ccc2nc(N3CC(O)C3)n3c2c1OCC3c1cccnc1,,CO,,Cl,,test
US20070179165A1,CC(=O)Cl.CCCN(CCC)c1nc2[nH]cc(-c3c(C)cc(C)cc3C)c2c(=O)n1C>>CCCN(CCC)c1nc2c(c(-c3c(C)cc(C)cc3C)cn2C(C)=O)c(=O)n1C,,CC#N,O,[H-].[Na+],,test
US20080085890A1,CN1CCC(N(C)c2ccc(N)cc2)C1.CO/C=C1/C(=O)NC(=O)c2ccc(Br)cc21>>CN1CCC(N(C)c2ccc(N/C=C3\C(=O)NC(=O)c4ccc(Br)cc43)cc2)C1,,CN(C)C=O,,CCN(CC)CC,,test
US20040152898A1,Nc1ccc(C(F)(C(F)(F)F)C(F)(F)Br)cc1Cl.O=C1CCC(=O)N1Br>>Nc1ccc(C(F)(C(F)(F)F)C(F)(F)Br)cc1Br,,CC#N,,,,test
US20110105761A1,CC(C)(C)C(=O)CCl.Cc1cc(C)c(-n2ccnc2)c(C)c1>>Cc1cc(C)c(-n2cc[n+](CC(=O)C(C)(C)C)c2)c(C)c1.[Cl-],,C1CCOC1,,,,test
US20070185101A1,CC(C)(C)OC(=O)N1CCC(CO)CC1.Sc1ccccn1>>CC(C)(C)OC(=O)N1CCC(CSc2ccccn2)CC1,,c1ccccc1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060128702A1,Fc1ccc(-c2cc(Cl)c3ccccc3n2)cc1.c1c[nH]cn1>>Fc1ccc(-c2cc(-n3ccnc3)c3ccccc3n2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20130102599A1,CC(=O)Nc1ccc(S(=O)(=O)N=[N+]=[N-])cc1.CCOC(=O)CC(=O)c1c(F)cccc1F>>CCOC(=O)C(=[N+]=[N-])C(=O)c1c(F)cccc1F,,CC#N,,CCN(CC)CC,,test
US05877202,CCCCN(C)C(=O)CCCCCCCNC(=O)OC(C)(C)C.Cl>>CCCCN(C)C(=O)CCCCCCCN.Cl,,C1COCCO1,,,,test
US20140249126A1,CCn1cc(C(=O)O)c(=O)c2cc(F)c(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)c21.NCCN1CCCC1>>CCn1cc(C(=O)NCCN2CCCC2)c(=O)c2cc(F)c(OCc3ccc(OC)cc3)c(OCc3ccc(OC)cc3)c21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030134853A1,COC(=O)c1ccc2c(c1)nc(-c1ccc(OCc3ccccc3)cc1)n2C1CCCCC1>>O=C(O)c1ccc2c(c1)nc(-c1ccc(OCc3ccccc3)cc1)n2C1CCCCC1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20080015199A1,CC(=O)O.COc1cc(OCCF)c(F)c(C(Nc2ccc(-c3noc(C)n3)cc2)c2nn(-c3ncccn3)c(=O)[nH]2)c1>>CC(=O)O.COc1cc(OCCF)c(F)c(C(Nc2ccc(C(=N)N)cc2)c2nn(-c3ncccn3)c(=O)[nH]2)c1,[Fe],CO,,O,,test
US04866064,CCCCCCCBr.Nc1nnc(S)s1>>CCCCCCCSc1nnc(N)s1,,CCO,O,[Na+].[OH-],,test
US20040209921A1,COc1ccccc1B(O)O.O=Cc1ncccc1Br>>COc1ccccc1-c1cccnc1C=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20120022065A1,COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ncnc2cc1O.NC(=O)C1(C(=O)Nc2ccc(F)cc2)CC1.OCCCN1CCOCC1>>COc1cc2c(Oc3ccc(N(C(=O)C4(C(N)=O)CC4)c4ccc(F)cc4)cc3F)ncnc2cc1OCCCN1CCOCC1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090099228A1,CCn1nc(C)cc1CCNC(=O)OCc1ccccc1>>CCn1nc(C)cc1CCN,[Pd],CO,,,,test
US20140336190A1,Brc1ncccn1.Cc1noc(C)c1-c1cc(C(=O)C2CCCO2)c2nc(C3CC3)n(C(=O)OC(C)(C)C)c2c1>>Cc1noc(C)c1-c1cc(C(O)(c2ncccn2)C2CCCO2)c2nc(C3CC3)[nH]c2c1,,ClCCl,,[Li]CCCC,,test
US06498251B1,CC(C)(C)OC(=O)N1CCc2sc(C(=O)O)cc2C1.CNC>>CN(C)C(=O)c1cc2c(s1)CCN(C(=O)OC(C)(C)C)C2,,C1CCOC1,,,,test
US20030069273A1,NNc1ccc([N+](=O)[O-])cc1.O=c1nc(-c2ccccc2O)oc2ccccc12>>O=[N+]([O-])c1ccc(-n2nc(-c3ccccc3O)nc2-c2ccccc2O)cc1,,CCO,,CCN(CC)CC,Cl,test
US04598087,CN[C@@H]1CCCC[C@H]1N1CCCC1.O=C(O)COc1ccc(Cl)cc1>>CN(C(=O)COc1ccc(Cl)cc1)[C@@H]1CCCC[C@H]1N1CCCC1,,ClCCl,,CCOCC,,test
US20090005410A1,CCOC(=O)c1ccc(S(=O)(=O)Cl)cc1F.Nc1ccc(Cl)cc1-n1nnc2ncccc21>>CCOC(=O)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-n2nnc3ncccc32)cc1F,,CCOC(C)=O,c1ccncc1,CS(=O)(=O)Cl,,test
US04665189,N.O=C(O)C=Cc1cccc(CC(=O)O)c1>>NC(=O)c1cccc(C=CC(=O)O)c1,,N,,CN(C)C=O,,test
US04925846,CC(=O)CCl.CCc1c(OC)nc2nc(C(N)=S)cn2c1C>>CCc1c(OC)nc2nc(-c3nc(C)cs3)cn2c1C,,CCO,,,,test
US05322848,Cc1ccc(S(=O)(=O)Cl)cc1.O=C(OCc1ccccc1)N1CC[C@@H](O)C1>>Cc1ccc(S(=O)(=O)O[C@@H]2CCN(C(=O)OCc3ccccc3)C2)cc1,,c1ccncc1,,,,test
US04419516,N#CCCl.S=c1[nH]cc2ccccn12>>N#CCSc1ncc2ccccn12,,Cc1ccccc1,,CCN(CC)CC,,test
US04734125,O=C(CCl)Nc1ccnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl.O=[N+]([O-])O>>O=C(CCl)Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20140087949A1,CCOC(=O)/C=C(\C#CC1(O)C(C)=CC2(CC1(C)C(F)(F)F)OC(C)C(C)O2)C(F)(F)F>>CCOC(=O)/C=C(\C#CC1(O)C(C)=CC(=O)CC1(C)C(F)(F)F)C(F)(F)F,Cl,CC(C)=O,,O,,test
US20080176830A1,O=C(CCl)Nc1ccc(-c2ccc(C(F)(F)F)cc2)cc1CO>>O=C1COCc2cc(-c3ccc(C(F)(F)F)cc3)ccc2N1,,C1CCOC1,,[H-].[Na+],,test
US06124317,BrCCCCBr.Oc1ccc(C(F)(F)F)cc1>>FC(F)(F)c1ccccc1OCCCCBr,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US04868305,CCOC=C(C(=O)OCC)C(=O)OCC.Nc1ccc(F)c(Cl)c1>>CCOC(=O)C(=CNc1ccc(F)c(Cl)c1)C(=O)OCC,,CCO,,,,test
US20140135320A1,COCOc1ccc(C(C)(C)C)cc1B(O)O.FC(F)(F)c1cnc(Cl)nc1>>COCOc1ccc(C(C)(C)C)cc1-c1ncc(C(F)(F)F)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US05891909,Cc1cc(OCCCO)cc(OCc2ccccc2C(F)(F)F)c1>>Cc1cc(OCCC=O)cc(OCc2ccccc2C(F)(F)F)c1,,ClCCl,,CCN(C(C)C)C(C)C,CS(C)=O,test
US08350046B2,Cn1cc(C(=O)Cl)c(C(F)F)n1.Nc1ccccc1Cl>>Cn1cc(C(=O)Nc2ccccc2Cl)c(C(F)F)n1,,Cc1ccccc1,,,,test
US20130331378A1,COC(=O)c1cccc(Cc2c(N3CCOCC3)nn3ccccc23)n1>>O=C(O)c1cccc(Cc2c(N3CCOCC3)nn3ccccc23)n1,,CO,,Cl,[K+].[OH-],test
US20040157901A1,C1CSCSC1.COC(=O)CBr>>COC(=O)CSCCCS,,C1CCOC1,,[H-].[Na+],,test
US20150376130A1,COC(=O)C1CSCC1=O.NO>>COC(=O)c1cscc1N,,CC#N,,Cl,,test
US20110136763A1,CCOC(=O)CC1OB(O)c2cc(O)cc(C)c21.O=[N+]([O-])c1cccc(Cl)n1>>CCOC(=O)CC1OB(O)c2cc(Oc3cccc(Cl)n3)cc(C)c21,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080139639A1,CNCc1cc(-c2ccccc2)n(S(=O)(=O)c2ccccc2C(=O)OC)c1.Cl>>CNCc1cc(-c2ccccc2)n(S(=O)(=O)c2ccccc2C(=O)OC)c1.Cl,,CCOC(C)=O,,,,test
US20020193596A1,COC(=O)c1ccc(COCc2cccnc2)cc1-c1ccccc1>>O=C(O)c1ccc(COCc2cccnc2)cc1-c1ccccc1,,CO,,[Li+].[OH-],,test
US20160214956A1,CCOC(=O)c1cnn(-c2cccc(-c3cccc(Cl)c3CCc3ccc(OCCCC(F)(F)F)cc3C)n2)c1C(F)(F)F>>Cc1cc(OCCCC(F)(F)F)ccc1CCc1c(Cl)cccc1-c1cccc(-n2ncc(C(=O)O)c2C(F)(F)F)n1,,CCO,O,[Na+].[OH-],,test
US20090075989A1,Cc1noc(=O)c2ccc(N)cc12.O=C(O)C(=O)c1ccc([N+](=O)[O-])cc1>>Cc1noc(=O)c2ccc(NC(=O)C(=O)c3ccc([N+](=O)[O-])cc3)cc12,,CC(=O)N(C)C,,O=S(Cl)Cl,,test
US20150045349A1,CC(=O)[O-].N#Cc1c(Cl)cc(CBr)n(-c2ccccc2Cl)c1=O>>CC(=O)OCc1cc(Cl)c(C#N)c(=O)n1-c1ccccc1Cl,,CC(C)=O,,O,,test
US07709468B2,CSc1nccc(-c2c(-c3ccc(F)cc3)nc3c(C)nccn23)n1.O=S([O-])OO>>Cc1nccn2c(-c3ccnc(S(C)(=O)=O)n3)c(-c3ccc(F)cc3)nc12,,ClCCl,O,CO,,test
US20040254241A1,CCOC(=O)/C(C#N)=C(/c1ccc(OCOC)cc1)C(C)C>>COCOc1ccc(/C(=C(\C#N)C(=O)O)C(C)C)cc1,,CO,O,[Li+].[OH-],,test
US06586633B1,CCC#N.Cc1cccc(Br)c1.O=S(=O)(O)O>>CCC(=O)c1cccc(C)c1,,CCOCC,O,II,[Mg],test
US20060115425A1,CC(NC(=O)C(C)(C)Oc1ccc(C(F)(F)F)cn1)C(Cc1ccc(O)cc1)c1cc(F)cc(C#N)c1.CS(=O)(=O)OCCF>>CC(NC(=O)C(C)(C)Oc1ccc(C(F)(F)F)cn1)C(Cc1ccc(OCCF)cc1)c1cc(F)cc(C#N)c1,,CCOCC,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080096921A1,CC(C)c1onc(COC2CCCC2)c1CO.COC(=O)c1ccc2cc(-c3ccc(O)cc3)ccc2n1>>COC(=O)c1ccc2cc(-c3ccc(OCc4c(COC5CCCC5)noc4C(C)C)cc3)ccc2n1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130296290A1,CC(C)(C)OC(=O)N1CCN(C(=O)NN)CC1.O=C(O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1>>CC(C)(C)OC(=O)N1CCN(C(=O)NNC(=O)[C@@H]2CC[C@@H]3CN2C(=O)N3OCc2ccccc2)CC1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06211202B1,CC(C)(C)C=O.Cc1cc(Br)cnc1F>>Cc1cc(CO)cnc1F,,CCOCC,,[Li]CCCC,,test
US20090093491A1,Brc1cnc(C#CCCn2cncn2)cn1>>Brc1cnc(CCCCn2cncn2)cn1,O=[Pt]=O,CO,,,,test
US20030195211A1,Nc1c(C(=O)Nc2ccccc2Cl)cccc1C(F)(F)F.O=C(Cl)CCl>>O=c1c2cccc(C(F)(F)F)c2nc(CCl)n1-c1ccccc1Cl,,CC(=O)O,,,,test
US20140045862A1,COc1ccc(CN(c2ccncn2)S(=O)(=O)c2ccc(O[C@H]3CCC[C@@H]3c3ccnn3C)c(F)c2F)c(OC)c1>>Cn1nccc1[C@H]1CCC[C@@H]1Oc1ccc(S(=O)(=O)Nc2ccncn2)c(F)c1F,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US05250517,CCOC(=O)CCNC(=O)CCCCNC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCCCC(=O)NCCC(=O)O,,CO,,Cl,[Na+].[OH-],test
US20100222352A1,CC(C)=CCBr.Oc1cc(Nc2ccccn2)ccc1Cl>>CC(C)=CCOc1cc(Nc2ccccn2)ccc1Cl,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05990146,CN(C)C(=S)Cl.Oc1ccc2c(c1)ncn2-c1ccccc1>>CN(C)C(=S)Oc1nc2ccccc2[nH]1,,C1CCOC1,,CN(C)C=O,[H-].[Na+],test
US20050154023A1,Brc1cccc2cc[nH]c12.CN(C)C=O.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(O)c1c[nH]c2c(Br)cccc12,,CN(C)C=O,,,,test
US20100249123A1,CC(C)(CN)c1ccc([N+](=O)[O-])cc1Cl.O=C(O)c1n[nH]c2ccccc12>>CC(C)(CNC(=O)c1n[nH]c2ccccc12)c1ccc([N+](=O)[O-])cc1Cl,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20090318408A1,CCN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Cl)ncc21.COc1cc(C(=O)NC2CCN(C)CC2)ccc1N>>CCN1C(=O)C(F)(F)CN(C2CCCC2)c2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc21,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05786302,Cn1nc(C(F)(F)F)cc1O.O=[N+]([O-])c1cc(Cl)c(Cl)cc1F>>Cn1nc(C(F)(F)F)cc1Oc1cc(Cl)c(Cl)cc1[N+](=O)[O-],,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080004309A1,CCOC(=O)c1nc(Br)c2nc(-c3ccccc3)sc2c1O.OB(O)c1ccccc1>>CCOC(=O)c1nc(-c2ccccc2)c2nc(-c3ccccc3)sc2c1O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20050261177A1,CC(C)(C)OC(=O)N1CCC(CO)CC1.CCC(Br)CCCCBr>>CC(Br)CCCOCC1CCN(C(=O)OC(C)(C)C)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US20080027048A1,CC(C)COc1ccc(Br)cc1C#N.CC(C)OB(OC(C)C)OC(C)C>>CC(C)COc1ccc(B(O)O)cc1C#N,,C1CCOC1,Cc1ccccc1,Cl,,test
US20140179695A1,Brc1cnc2[nH]ccc2c1.CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1=NC2(CO1)c1cc(B3OC(C)(C)C(C)(C)O3)ccc1OCC21CC1>>NC1=NC2(CO1)c1cc(-c3cnc4[nH]ccc4c3)ccc1OCC21CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US05958821,C1=CCCCC1.CC#N.O=C1c2ccccc2C(=O)N1O.O=O>>O=C1C=CCCC1.OC1C=CCCC1,,CC#N,,,,test
US20100222317A1,O=C(NCC1(N2CCCCC2)CC(CO)C1)c1ccc(Cl)cc1Cl.O=C(O)Cc1cccs1>>CC(=S)OCC1CC(CNC(=O)c2ccc(Cl)cc2Cl)(N2CCCCC2)C1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100130495A1,CCC=O.Cn1cc(-c2ccc(Nc3nc4c(c(N(CCO)c5ccccc5)n3)CNCC4)cc2)cn1>>CCCN1CCc2nc(Nc3ccc(-c4cnn(C)c4)cc3)nc(N(CCO)c3ccccc3)c2C1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20060122181A1,O=C(OCc1nc(-c2ccc(CO)cc2)cs1)c1ccccc1.O=S(Cl)Cl>>O=C(OCc1nc(-c2ccc(CCl)cc2)cs1)c1ccccc1,,ClC(Cl)Cl,,CN(C)C=O,,test
US20090275523A1,COC(=O)[C@H](CC(F)(F)Cc1ccccc1)NC(=O)OCc1ccccc1>>COC(=O)[C@@H](N)CC(F)(F)Cc1ccccc1,,CO,,,,test
US20110201687A1,CNc1cc(C(=O)Nc2c(Cl)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2C(F)(F)F)ccc1I.N#C[Cu]>>CNc1cc(C(=O)Nc2c(Cl)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2C(F)(F)F)ccc1C#N,,CN(C)C=O,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US05707997,CCCCC(=O)CC(=O)OC.Nc1cc[nH]n1>>CCCCc1cc(O)n2nccc2n1,,Cc1ccccc1,,,,test
US20120244120A1,CC(C)(C)OC(=O)Nc1cc(C(C)(C)COc2ccc(N)c3ccccc23)ccn1.Cc1ccc(-n2nc(C(C)(C)C)cc2N)cc1.O=C(n1ccnc1)n1ccnc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCC(C)(C)c3ccnc(NC(=O)OC(C)(C)C)c3)c3ccccc23)cc1,,ClCCl,,,,test
US20030187014A1,CNC.Cc1nn(-c2ccccn2)c2nc3ccccc3c(Cl)c12>>Cc1nn(-c2ccccn2)c2nc3ccccc3c(N(C)C)c12,,O,,C1CCOC1,,test
US20100331320A1,CC(=O)O.COCC(O)(CC=O)c1ccccc1.C[C@H](N)c1ccc(Br)cc1>>COC[C@]1(c2ccccc2)CCN([C@@H](C)c2ccc(Br)cc2)C(=O)O1,,C1CCOC1,,,,test
US20140038957A1,Cc1cnc2[nH]cnc(N3CCC(N)CC3)c1-2.ClCCCl.O=C(O)c1cccc(OCCN2CCC(F)(F)C2)c1>>Cc1cnc2[nH]cnc(N3CCC(NC(=O)c4cccc(OCCN5CCC(F)(F)C5)c4)CC3)c1-2.Cl,,CN1CCCC1=O,ClCCl,CCN(C(C)C)C(C)C,On1nnc2ccccc21,test
US20140335201A1,Cc1nc(O[C@@H]2CC[C@@H](C(C)C)CC2)c(Br)cc1[N+](=O)[O-]>>Cc1nc(O[C@@H]2CC[C@@H](C(C)C)CC2)c(Br)cc1N,[Fe],CCO,O,[Cl-].[NH4+],,test
US20140363452A1,CC(C)(C)OC(=O)NC1(C(=O)O)COC1.CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)NCCc1ccccc1)OC)N(C)C(=O)[C@@H](N)C(C)C>>CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)NCCc1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)C1(NC(=O)OC(C)(C)C)COC1)C(C)C,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120277208A1,CC(C)(C)O.COC(=O)c1cc(Oc2cnc(C(=O)O)cn2)cc(OC(C)C)c1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>COC(=O)c1cc(Oc2cnc(NC(=O)OC(C)(C)C)cn2)cc(OC(C)C)c1,,O,,CCN(CC)CC,,test
US20040058978A1,CCOC(=C1C(=O)N(C(C)=O)c2ccc([N+](=O)[O-])cc21)c1ccccc1.Nc1ccc(NC(=O)CN2CCOCC2)cc1>>O=C(CN1CCOCC1)Nc1ccc(N/C(=C2\C(=O)Nc3ccc([N+](=O)[O-])cc32)c2ccccc2)cc1,,CN(C)C=O,CO,[Na+].[OH-],,test
US20100130474A1,CC(CC(=O)O)CN1CCCCC1.COc1cncc(-c2cc(N)n(C(=O)OC(C)(C)C)n2)c1.O=C(Cl)C(=O)Cl>>COc1cncc(-c2cc(NC(=O)CC(C)CN3CCCCC3)[nH]n2)c1.O=CO,,CC#N,CN(C)C=O,Cl,Cl,test
US04014864,CC(=O)OC(C)=O.CCN(CC(OC(C)=S)c1nc2ccccc2s1)c1cccc([N+](=O)[O-])c1>>CCN(CC(OC(C)=S)c1nc2ccccc2s1)c1cccc(NC(C)=O)c1,[Pd],CC(=O)OC(C)=O,,CCO,,test
US06541580B1,C=Cc1ccccc1.CCCCC(CCCC)c1ccnc(-c2cc(C(CCCC)CCCC)ccn2)c1>>C=C(C)C.C=Cc1ccccc1,,C1CCOC1,,O=O,,test
US20090318702A1,CCOC(=O)CC(=O)c1cc(Br)c(OC)cc1OC.COC(OC)N(C)C>>CCOC(=O)C(=CN(C)C)C(=O)c1cc(Br)c(OC)cc1OC,,Cc1ccccc1,,,,test
US04812483,CC(C)(CO)COCc1ccc(F)c(Cc2ccccc2)c1>>CC(C)(C=O)COCc1ccc(F)c(Cc2ccccc2)c1,,CCOCC,ClCCl,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20020055631A1,COC(=O)c1ccc(-c2ccc(C=O)cc2OC)cc1>>COC(=O)c1ccc(-c2ccc(CO)cc2OC)cc1,,CCOC(C)=O,CO,[BH4-].[Na+],,test
US20120277244A1,CC(C)(C)OC(=O)CBr.CC(C)(C)OC(=O)NC(CN)(c1cc(Br)ccc1F)C(F)F>>CC(C)(C)OC(=O)CNCC(NC(=O)OC(C)(C)C)(c1cc(Br)ccc1F)C(F)F,,CC#N,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US05360802,O=C(NS(=O)(=O)c1cccc([N+](=O)[O-])c1)c1ccccc1>>Nc1cccc(S(=O)(=O)NC(=O)c2ccccc2)c1,[Pd],CCO,O,,,test
US20110014186A1,CC(C)(C)C(=O)Cl.c1ccc2c3c([nH]c2c1)CNCC3>>CC(C)(C)C(=O)N1CCc2c([nH]c3ccccc23)C1,,ClCCl,,CCN(CC)CC,,test
US05026856,CC1COc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23.Nc1cccc2c1CNC2>>CC1COc2c(N3Cc4cccc(N)c4C3)c(F)cc3c(=O)c(C(=O)O)cn1c23,,CN(C)C=O,,,,test
US20090281131A1,COC(=O)C1CC(C#N)(c2ccc(OC)c3oc4ccccc4c23)CCC1=O>>COc1ccc(C2(C#N)CCC(=O)CC2)c2c1oc1ccccc12,,CS(C)=O,O,[Cl-].[Na+],,test
US20140343032A1,CC(C)(C)OC(=O)N1C2COCC1CC(=O)C2.NO>>CC(C)(C)OC(=O)N1C2COCC1CC(=NO)C2,,CCO,,Cl,,test
US20060281802A1,Nc1cc(C(F)(F)F)ccc1NCCO.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>OCCn1c(C(F)(F)F)nc2cc(C(F)(F)F)ccc21,,ClCCl,,CCN(CC)CC,CN(C)c1ccccn1,test
US05494928,CCOC(=O)c1[nH]c2cccc(C)c2c1OC>>COc1c(C(=O)O)[nH]c2cccc(C)c12,,CCO,,[Na+].[OH-],,test
US20080085890A1,COc1cc(CO)ccc1-c1ccccc1.O=S(Cl)Cl>>COc1cc(CCl)ccc1-c1ccccc1,,ClCCl,,,,test
US04797492,CC(C)(C)C(=O)Nc1cc(C(F)(F)F)on1>>Nc1cc(C(F)(F)F)on1,,OCCO,,Cl,,test
US20140031336A1,CC(=O)N1c2ccc(-c3ccc(C(=O)O)cn3)cc2[C@H](Nc2ccc(C#N)cn2)C[C@@H]1C.CN(C)CCN>>CC(=O)N1c2ccc(-c3ccc(C(=O)NCCN(C)C)cn3)cc2[C@H](Nc2ccc(C#N)cn2)C[C@@H]1C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100056577A1,CNCc1cn(S(=O)(=O)c2cncc(C)c2)c(-c2cccnc2F)c1F.O=C(O)/C=C/C(=O)O>>CNCc1cn(S(=O)(=O)c2cncc(C)c2)c(-c2cccnc2F)c1F.O=C(O)/C=C/C(=O)O,,CCO,CCOC(C)=O,,,test
US20090264650A1,CCCC[Sn](CCCC)(CCCC)c1ccccn1.O=C1C(Cc2ccc(Br)cc2Cl)CCN1C1CCCCC1>>O=C1C(C(c2ccccn2)c2ccccc2Cl)CCN1C1CCCCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCOC(C)=O,O,test
US20080214654A1,COc1cc(CN(CCNC(=O)OC(C)(C)C)C(=O)c2ccc(F)cc2)ccc1OCc1ccccc1.Cl>>COc1cc(CN(CCN)C(=O)c2ccc(F)cc2)ccc1OCc1ccccc1.Cl,,C1COCCO1,CO,,,test
US05840917,CN(C)C=O.O=C(O)c1csc(Br)c1>>O=Cc1cc(C(=O)O)cs1,,C1CCOC1,,[Li]CCCC,,test
US20060079523A1,Cc1ccc(N)cc1C1CCN(C(=O)OC(C)(C)C)CC1.O=C(Cl)OCc1ccccc1>>Cc1ccc(NC(=O)OCc2ccccc2)cc1C1CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,ClCCl,O=C([O-])[O-].[K+].[K+],test
US06350907B1,Cc1cc(N)ccc1-c1cccc(C#N)c1.[I-]>>Cc1cc(I)ccc1-c1cccc(C#N)c1,,Cl,O,O=N[O-].[Na+],,test
US04098898,CSC(=C[N+](=O)[O-])S(C)=O.Cc1nc[nH]c1CSCCN.NCC(F)(F)F>>Cc1nc[nH]c1CSCCNC(=C[N+](=O)[O-])NCC(F)(F)F,,CO,O,Cl,[K+].[OH-],test
US20030055044A1,Nc1ncccc1C(=O)O.O=C(Cl)c1ccccc1C(F)(F)F>>O=c1oc(-c2ccccc2C(F)(F)F)nc2ncccc12,,c1ccncc1,,O,,test
US20060100283A1,CC(C)(C)OC(=O)N(c1cc(OC[C@@H]2CO2)ccc1OCc1ccccc1)S(C)(=O)=O.Oc1ccc([C@@H]2CC[C@@H](NCc3ccccc3)CC2)cc1>>CS(=O)(=O)Nc1cc(OC[C@@H](O)CN(Cc2ccccc2)[C@@H]2CC[C@@H](c3ccc(O)cc3)CC2)ccc1OCc1ccccc1,,CCO,,Cl,,test
US04988385,CNC.COC(OC)OC.N#CCC(=O)c1cccc(Oc2ccccc2)c1>>CN(C)C=C(C#N)C(=O)c1cccc(Oc2ccccc2)c1,,CCO,,,,test
US20130267493A1,COC(=O)c1c[nH]c2cc(Cl)c(-c3ccc(C4CCN4S(C)(=O)=O)cc3)cc12>>CS(=O)(=O)N1CCC1c1ccc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)cc1,,CO,,[Na+].[OH-],,test
US20080293714A1,CC(N(C)Cc1cc(CCC(C)(C)O)c2cc(-c3nn(C(=O)OC(C)(C)C)c4cc(-c5cnco5)sc34)n(C(=O)OC(C)(C)C)c2c1)C(C)(C)C>>CC(N(C)Cc1cc(CCC(C)(C)O)c2cc(-c3n[nH]c4cc(-c5cnco5)sc34)[nH]c2c1)C(C)(C)C,,ClCCl,O=C(O)C(F)(F)F,,,test
US20140045862A1,COc1ccc(CNc2ccncn2)c(OC)c1.O=S(=O)(Cl)c1cc(Br)c(F)cc1F>>COc1ccc(CN(c2ccncn2)S(=O)(=O)c2cc(Br)c(F)cc2F)c(OC)c1,,C1CCOC1,,C1CN2CCN1CC2,,test
US20060199817A1,Clc1nncc2cc(Br)ccc12.OC1CCNC1>>OC1CCN(c2nncc3cc(Br)ccc23)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20050267049A1,CC(=O)O[C@@H](CC[C@H]1C(=O)N(c2ccc(I)cc2)[C@@H]1c1ccc(O[Si](C)(C)C(C)(C)C)cc1)c1ccc(F)cc1>>CC(C)(C)[Si](C)(C)Oc1ccc([C@@H]2[C@@H](CC[C@H](O)c3ccc(F)cc3)C(=O)N2c2ccc(I)cc2)cc1,,CO,,[C-]#N.[Na+],,test
US20160129002A1,CCOC(=O)CC(=O)COCC1CC1.NC(N)=S>>O=c1cc(COCC2CC2)[nH]c(=S)[nH]1,,CCO,,Cl,[Na],test
US20040092507A1,C1CNCCN1.N#Cc1ccc(C(F)(F)F)cc1F>>N#Cc1ccc(C(F)(F)F)cc1N1CCNCC1,,CCOC(C)=O,CS(C)=O,,,test
US20080300280A1,Cc1cccc(S(N)(=O)=O)c1C#N.O=C(Cl)OCc1ccccc1>>Cc1cccc(S(=O)(=O)NC(=O)OCc2ccccc2)c1C#N,,CC(C)=O,,[Na+].[OH-],,test
US04581370,CCCCCCCn1ccnc1.Cc1ccc(S(=O)(=O)[O-])cc1.OC/C=C\Cc1ccc(Cl)cc1>>CCCCCCCn1cc[n+](C/C=C\Cc2ccc(Cl)cc2)c1.Cc1ccc(S(=O)(=O)[O-])cc1,,CC#N,,,,test
US20070082912A1,CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(C(F)(F)F)ccc2OCc2ccc(F)cc2)c1>>Cc1ccc(-c2cc(C(F)(F)F)ccc2OCc2ccc(F)cc2)n1-c1cccc(C(=O)O)c1,,CCOC(C)=O,,CCO,[Na+].[OH-],test
US20160200704A1,C=CC=O.COC(=O)c1ccc(N)c(F)c1>>COC(=O)c1cc(F)c2ncccc2c1,,Cl,,O=C([O-])O.[Na+],,test
US20120129856A1,CCOC(=O)C(C)(C)CCCCC(Br)c1ccccc1Cl.c1cc2c(s1)CCNC2>>CCOC(=O)C(C)(C)CCCCC(c1ccccc1Cl)N1CCc2sccc2C1,,CN(C)C=O,O,[Na+].[OH-],O=C([O-])[O-].[K+].[K+],test
US20040102436A1,CC(C)N(CCCCBr)c1cnc(-c2ccccc2)c(-c2ccccc2)n1.COC(=O)CS>>COC(=O)CSCCCCN(c1cnc(-c2ccccc2)c(-c2ccccc2)n1)C(C)C,,CC#N,,[I-].[K+],,test
US04158007,CCO.CCOC(=O)C(CC)C(=O)OC.O=C1C=CCCC1>>CCOC(=O)C(C)(C(=O)OCC)C1CCCC(=O)C1,,CC(=O)O,,[Na],,test
US20080234499A1,COC(=O)[C@@H](N)CSc1ccccc1F>>N[C@H](CO)CSc1ccccc1F,,C1CCOC1,O,[H-].[Na+],,test
US20090005353A1,CC(C)N1C(=O)C(Cl)=C(c2ccccc2)S1(=O)=O.CS(=O)(=O)Oc1ccc(CCN)cc1>>CC(C)N1C(=O)C(NCCc2ccc(OS(C)(=O)=O)cc2)=C(c2ccccc2)S1(=O)=O,,CC#N,,,,test
US20030096828A1,COC(=O)C(CC1CCN(C(=O)OC(C)(C)C)CC1)CC1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(CC(CC2CCN(C(=O)OC(C)(C)C)CC2)C(=O)O)CC1,,CO,,Cl,[Na+].[OH-],test
US20100222338A1,CC(C)(C)Cc1ccc(Cl)nn1.CC(C)(C)S(=O)/N=C/CC1(O[Si](C)(C)C(C)(C)C)CCC1>>CC(C)(C)Cc1cc(C(CC2(O[Si](C)(C)C(C)(C)C)CCC2)NS(=O)C(C)(C)C)c(Cl)nn1,,C1CCOC1,O,CC1(C)CCCC(C)(C)N1,[Li]CCCC,test
US20120035214A1,O=C1C[C@@H](c2cccnc2)[C@H](c2ccc(Br)cc2Cl)C(=O)N1>>Clc1cc(Br)ccc1[C@@H]1CNCC[C@H]1c1cccnc1,,CO,,ClCCl,,test
US20030013875A1,CCCCCCN.CCOC(=O)C1C(CCl)C1(C)c1cccc([N+](=O)[O-])c1>>CCCCCCN1CC2C(C1=O)C2(C)c1cccc([N+](=O)[O-])c1,,O,,O=C([O-])O.[Na+],,test
US20140135318A1,CCCCc1c(-c2ccc(C(=O)OC(C)(C)C)cc2C(=O)N2Cc3ccccc3C[C@H]2CO)c(C(=O)OCC)nn1-c1ccccc1.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>CCCCc1c(-c2ccc(C(=O)OC(C)(C)C)cc2C(=O)N2Cc3ccccc3C[C@H]2CN=[N+]=[N-])c(C(=O)OCC)nn1-c1ccccc1,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020072624A1,C[C@]12C[C@H](c3ccc(OCCOCCO)cc3)C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CCC2=O.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCCOCCOc2ccc([C@H]3C[C@]4(C)C(=O)CC[C@H]4[C@@H]4CCC5=CC(=O)CCC5=C34)cc2)cc1,,c1ccncc1,,CN(C)c1ccccn1,,test
US05034370,C=O.CCCCCCCCCCCCc1ccc(O)c(C(=O)O)c1.Cc1ccc(C)cc1>>CCCCCCCCCCCCc1ccc(O)c(C(=O)O)c1.Cc1ccc(C)c(C=O)c1,,CC(=O)O,,O=S(=O)(O)O,,test
US05112922,CCCCCCCCNC(=O)CCCCBr.CNC>>CCCCCCCCNC(=O)CCCCN(C)C,,CCO,Cl,,,test
US20150266867A1,CC(C)(C)OC(=O)NCC(=O)/C=C(\N)C[C@H]1NC(=O)[C@H]1N.CC(C)(C)OC(=O)Nc1nc(/C(=N/OC(C)(C)C(=O)OC(C)(C)C)C(=O)O)cs1>>CC(C)(C)OC(=O)NCC(=O)/C=C(\N)C[C@H]1NC(=O)[C@H]1NC(=O)/C(=N\OC(C)(C)C(=O)OC(C)(C)C)c1csc(NC(=O)OC(C)(C)C)n1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05952362,CCO.Cc1ccc(OCC#N)cc1NS(C)(=O)=O.Cl>>CCOC(=N)COc1ccc(C)c(NS(C)(=O)=O)c1.Cl,,ClCCl,,,,test
US20160159797A1,Ic1n[nH]c2cnc(-c3cccnc3)cc12.OB(O)c1ccccc1>>c1ccc(-c2n[nH]c3cnc(-c4cccnc4)cc23)cc1,,CCO,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US04994104,COC(=O)CO.O=C(Oc1cc([N+](=O)[O-])c(F)cc1F)N1CCCC1>>COC(=O)COc1cc(F)c(OC(=O)N2CCCC2)cc1[N+](=O)[O-],,C1CCOC1,,[H-].[Na+],,test
US20160272596A1,COC(=O)c1ccc2c(CN3C(=O)[C@@H](NC(=O)OC(C)(C)C)CN(CCCNC(=O)OCc4ccccc4)c4ccccc43)c(OC)ccc2c1>>COC(=O)c1ccc2c(CN3C(=O)[C@@H](NC(=O)OC(C)(C)C)CN(CCCN)c4ccccc43)c(OC)ccc2c1,[Pd],CO,,,,test
US20090029965A1,COC(=O)/C=C/c1ccc(C(=O)O)cc1.c1ccc2c(c1)CCCCN2>>COC(=O)/C=C/c1ccc(C(=O)N2CCCCc3ccccc32)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20080113966A1,N[C@@H]1CC[C@@H](c2cccc(F)c2F)Cn2c(CC(F)(F)F)cnc21.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.O=C1Nc2ccccc2CCN1C1CCNCC1>>O=C(N[C@@H]1CC[C@@H](c2cccc(F)c2F)Cn2c(CC(F)(F)F)cnc21)N1CCC(N2CCc3ccccc3NC2=O)CC1,,C1CCOC1,,CCN(CC)CC,O=C([O-])[O-].[Na+].[Na+],test
US20140221333A1,CCOC(=O)[C@]1(C)CCCNC1.O=C(Cl)OCc1ccccc1>>CCOC(=O)[C@]1(C)CCCN(C(=O)OCc2ccccc2)C1,,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US04215220,OC(CCl)CNc1ccc(Cl)cc1Cl.c1c[nH]cn1>>OC(CNc1ccc(Cl)cc1Cl)Cn1ccnc1,,CN(C)C=O,CO,O,C[O-].[Na+],test
US20050032873A1,CCCN(CCC(=O)c1csc2ccc(F)cc12)C1COc2c(F)ccc(C(N)=O)c2C1>>CCCN(CCC(O)c1csc2ccc(F)cc12)C1COc2c(F)ccc(C(N)=O)c2C1,,CO,,O,[BH4-].[Na+],test
US05491144,CN.COC(=O)c1cc(Nc2ccccc2)c(Nc2ccccc2)cc1C(=O)OC>>CN1C(=O)c2cc(Nc3ccccc3)c(Nc3ccccc3)cc2C1=O,,OCCO,,,,test
US20160137648A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)OCC(NCCC#N)C(=O)O>>CC(C)(C)OCC(C(=O)O)N(CCC#N)C(=O)OC(C)(C)C,,CO,ClCCl,CCN(CC)CC,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(C)(O)C3CC3)CC2)c2ccnn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n([C@@H]2CC[C@@H](OCC(C)(O)C3CC3)CC2)c2ccnn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20080009524A1,CCOC(=O)C(C)C(=O)OCC.O=[N+]([O-])c1ccc(F)c(Br)c1>>CCOC(=O)C(C)(C(=O)OCC)c1ccc([N+](=O)[O-])cc1Br,,CN(C)C=O,,[H-].[Na+],,test
US20090054407A1,CC(C)(C)OC(=O)n1c(-c2ccc(O)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21.O=S(=O)(Cl)c1ccc(Cl)cc1F>>CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)c3ccc(Cl)cc3F)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21,,CC#N,,CCN(CC)CC,O,test
US06310056B1,C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(c3cn4cncc4s3)C[C@H]12.NC(=O)CI>>C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(c3c[n+]4cn(CC(N)=O)cc4s3)C[C@H]12.[I-],,CC(C)=O,,,,test
US04371604,CCCCCCCCCCCCCC(=O)O.Cc1c(O)ccc(O)c1C>>CCCCCCCCCCCCCC(=O)c1cc(O)c(C)c(C)c1O,,ClCCCl,,,,test
US06689922B1,CC(C)(CCCCCc1cccc(C=Cc2ccc(O[Si](C)(C)C(C)(C)C)c(O[Si](C)(C)C(C)(C)C)c2)c1)OC1CCCCO1>>CC(C)(O)CCCCCc1cccc(C=Cc2ccc(O)c(O)c2)c1,,C1CCOC1,O,O=S(=O)(O)O,,test
US20110118248A1,CC(=O)c1cc(S(=O)(=O)Cl)ccc1Cl.Nc1cc(Cl)cnc1Br>>CC(=O)c1cc(S(=O)(=O)Nc2cc(Cl)cnc2Br)ccc1Cl,,c1ccncc1,,,,test
US20130096088A1,CC(=O)N(Cc1ccc(-c2cc3nccc(Oc4ccc(NC(=O)NC5CC5)cc4F)c3s2)nc1)C1CCN(C(=O)OC(C)(C)C)CC1>>CC(=O)N(Cc1ccc(-c2cc3nccc(Oc4ccc(NC(=O)NC5CC5)cc4F)c3s2)nc1)C1CCNCC1,,CCOC(C)=O,,Cl,,test
US20110160229A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.CC1(C)O[C@@H]2C=C(I)[C@H](O)[C@@H]2O1>>CC1(C)O[C@@H]2C=C(I)[C@H](O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)[C@@H]2O1,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US05882628,OCc1c(I)c(CO)c(I)c(CO)c1I>>O=Cc1c(I)c(C=O)c(I)c(C=O)c1I,,CS(C)=O,,CCN(CC)CC,c1ccncc1,test
US20070281933A1,CC(C)(C)OC(=O)N1CCC(c2n[nH]c3c(C(N)=O)cc(Br)cc23)CC1.CC1(C)OB(c2cn[nH]c2)OC1(C)C>>CC(C)(C)OC(=O)N1CCC(c2n[nH]c3c(C(N)=O)cc(-c4cn[nH]c4)cc23)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05726165,CCCCO.O=[PH](O)C1CCCCC1>>CCCCO[PH](=O)C1CCCCC1,,CCCCO,,,,test
US20140107194A1,CNC.O=C(O)c1ccc(C[C@@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@H]2O)cc1>>CN(C)C(=O)c1ccc(C[C@@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@H]2O)cc1,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US20050261177A1,CC(C)(C)OC(=O)N1CCC(O)CC1.N#Cc1ccc(O)cc1>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(C#N)cc2)CC1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130116235A1,Cn1cc(-c2cncc(-n3ncc4c5c(sc4c3=O)CCCC5)c2C=O)cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c1=O>>Cn1cc(-c2cncc(-n3ncc4c5c(sc4c3=O)CCCC5)c2CO)cc(Nc2ccc(N3CCN(C4COC4)CC3)cn2)c1=O,,CO,,[BH4-].[Na+],,test
US20080292626A1,CC(C)[C@@H](NC(=O)OC(C)(C)C)c1nc2c(oc3ccc(F)cc32)c(=O)[nH]1.Cc1csc(CBr)c1>>Cc1csc(Cn2c([C@H](NC(=O)OC(C)(C)C)C(C)C)nc3c(oc4ccc(F)cc43)c2=O)c1,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160039825A1,CCOC(=O)c1cc2n(n1)CCCN(C(=O)CBr)C2.Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CCOC(=O)c1cc2n(n1)CCCN(C(=O)CNc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C2,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20080255358A1,BrCc1ccccc1.Cc1nc2c(O)cc(-n3ccccc3=O)cn2c1C>>Cc1nc2c(OCc3ccccc3)cc(-n3ccccc3=O)cn2c1C,,CN(C)C=O,,[H-].[Na+],,test
US20100035883A1,CN(C)C(=O)c1ccc(C2c3n[nH]c(=O)c4cccc(c34)NC2c2ccc(C=O)cc2)cc1.CNC>>CN(C)Cc1ccc(C2Nc3cccc4c(=O)[nH]nc(c34)C2c2ccc(C(=O)N(C)C)cc2)cc1,,ClCCl,,CC(=O)O,[BH4-].[Na+],test
US08236963B2,CC(C)(C)OC(=O)CBr.CCOC(=O)C1C(=O)N(C(=O)OCC)c2ccc(Cl)cc21>>CCOC(=O)N1C(=O)C(CC(=O)OC(C)(C)C)(C(=O)OCC)c2cc(Cl)ccc21,,O,,CN(C)C=O,,test
US05006530,CCOC(=O)c1c(C(C)C)nc(C(C)C)c(CO)c1-c1ccc(F)cc1.O=S(Cl)Cl>>CCOC(=O)c1c(C(C)C)nc(C(C)C)c(CCl)c1-c1ccc(F)cc1,,C1CCOC1,,CCOC(C)=O,c1ccncc1,test
US20140045862A1,COc1ccc(CN(c2ccncn2)S(=O)(=O)c2c(F)cc(O[C@H]3CCC[C@@H]3c3ccnn3C)cc2F)c(OC)c1>>Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20050208582A1,N#C[Cu]C#N.O=Cc1cc(Br)cc(F)c1F>>N#Cc1cc(F)c(F)c(C=O)c1,,CN1CCCC1=O,,CCOC(C)=O,O,test
US20070213371A1,Cc1cc(Br)c(CNCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C(F)(F)F.N#CBr>>Cc1cc(Br)c(CN(C#N)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C(F)(F)F,,CO,,O=C([O-])[O-].[Na+].[Na+],,test
US20060069123A1,CC(C)[Si](C(C)C)(C(C)C)n1ccc(Br)c1.O=C1CCN(C(=O)OCc2ccccc2)CC1>>CC(C)[Si](C(C)C)(C(C)C)n1ccc(C2(O)CCN(C(=O)OCc3ccccc3)CC2)c1,,C1CCOC1,,[Li]C(C)(C)C,,test
US20040092737A1,NCc1ccc2c(c1)Nc1nccnc1S2.O=C=Nc1ccccc1>>O=C(NCc1ccc2c(c1)Nc1nccnc1S2)Nc1ccccc1,,C1CCOC1,,,,test
US08653089B2,C[C@H](N)c1nc2ccc(F)cc2n1-c1cc(F)cc(F)c1.Clc1ncnc2c1ncn2C1CCCCO1>>C[C@H](Nc1ncnc2c1ncn2C1CCCCO1)c1nc2ccc(F)cc2n1-c1cc(F)cc(F)c1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20050234099A1,NC[C@@H](NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)ccc2c1)c1ccccc1.O=Cc1ccccc1>>O=C(N[C@H](CNCc1ccccc1)c1ccccc1)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)ccc2c1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20050065151A1,COc1cnc(-c2ccccc2)c2sc(NC(=O)c3ccccc3)nc12>>COc1cnc(-c2ccccc2)c2sc(N)nc12,,CO,,[Na+].[OH-],,test
US20160122323A1,CN(C(=O)c1ccc(NC(=O)OC(C)(C)C)cc1)c1cccc(Nc2ncc(Cl)c(-c3cn(S(=O)(=O)c4ccccc4)c4ccccc34)n2)c1>>CN(C(=O)c1ccc(N)cc1)c1cccc(Nc2ncc(Cl)c(-c3cn(S(=O)(=O)c4ccccc4)c4ccccc34)n2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05047540,CCCCCCCCCCCCCCCCSCC(CN)OC.O=S(=O)(Cl)CCCCl>>CCCCCCCCCCCCCCCCSCC(CNS(=O)(=O)CCCCl)OC,,ClCCl,,CCN(CC)CC,,test
US06245761B1,C=O.Cn1c(COc2ccc(Cl)cc2)cc2ccccc21.c1ccc(N2CCNCC2)cc1>>Cn1c(COc2ccc(Cl)cc2)c(CN2CCN(c3ccccc3)CC2)c2ccccc21,,CC(Cl)Cl,,Cl,CC(=O)[O-].[Na+],test
US05688798,Cc1ncc(CCl)c(N)n1.c1ccc2c(c1)CCNC2>>Cc1ncc(CN2CCc3ccccc3C2)c(N)n1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US04002640,CSCOc1ccc(N)c([N+](=O)[O-])c1>>CSCOc1ccc(N)c(N)c1,[Fe],CC(=O)O,,CO,,test
US20080200431A1,C=CCBr.Cn1nc(N2CCC(C(=O)NCCNS(=O)(=O)c3ccc4c(Cl)cn(S(=O)(=O)c5ccccc5)c4c3)CC2)ccc1=O>>C=CCN(CCNC(=O)C1CCN(c2ccc(=O)n(C)n2)CC1)S(=O)(=O)c1ccc2c(Cl)cn(S(=O)(=O)c3ccccc3)c2c1,,CC#N,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20070105904A1,O=Cc1ccc(OCc2ccccc2)nc1>>OCc1ccc(OCc2ccccc2)nc1,,O,,CO,[BH4-].[Na+],test
US20080085890A1,CCCOc1cnc(CN)cc1O.CO/C=C1/C(=O)NC(=O)c2ccc(C(C)(C)C)cc21>>CCCOc1cnc(CNC=C2C(=O)NC(=O)c3ccc(C(C)(C)C)cc32)cc1O,,CN(C)C=O,,,,test
US20140080806A1,Cc1ccc(-c2c(C(O)c3c(Cl)ncnc3Cl)cnn2C)cc1>>Cc1ccc(-c2c(C(=O)c3c(Cl)ncnc3Cl)cnn2C)cc1,,ClC(Cl)Cl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05304644,O=[N+]([O-])c1ccccc1Oc1ccccc1Cl>>Nc1ccccc1Oc1ccccc1Cl,[Ni],C1CCOC1,,[H][H],,test
US20150025071A1,CSc1nc2c(c(=O)[nH]1)CCCC2.Fc1ccc(N2CCNCC2)cc1>>O=c1[nH]c(N2CCN(c3ccc(F)cc3)CC2)nc2c1CCCC2,,CC(C)CCO,,,,test
US20030064995A1,CC(C)=O.COc1ccc(N)cc1N1CCN(C)CC1.Cl.Fc1ccc2[nH]cc(C3CCNCC3)c2c1>>COc1ccc(NC(=O)N2CCC(c3c[nH]c4ccc(F)cc34)CC2)cc1N1CCN(C)CC1.Cl,,CC#N,,CCN(CC)CC,Cl,test
US20010036944A1,COC(=O)c1ccccc1S(=O)(=O)Cl.Nc1ccccc1C(F)(F)F>>COC(=O)c1ccccc1S(=O)(=O)Nc1ccccc1C(F)(F)F,CN(C)c1ccncc1,c1ccncc1,,,,test
US20050004130A1,CC1CC(C)C(=O)C1=O.CC1CCC(NC(=O)C(N)CN)CC1>>CC1CC(C)(O)c2nc(C(=O)N[C@@H]3CC[C@@H](C)CC3)cnc21,,c1ccccc1,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US04855426,ClI.c1ccc2c(c1)OCO2>>Ic1ccc2c(c1)OCO2,,CC(=O)O,,O,,test
US20050038101A1,CC(C)(C)OC(=O)Nc1ccc(NC(=O)c2cc3cc(NC(=O)CC4CCOCC4)ccc3n2Cc2ccccc2F)cc1.Cl>>Cl.Nc1ccc(NC(=O)c2cc3cc(NC(=O)CC4CCOCC4)ccc3n2Cc2ccccc2F)cc1,,C1COCCO1,,,,test
US20060089371A1,COC(=O)[C@H](Cc1ccccc1)Nc1ncnc(Cl)c1C=O.OB(O)c1ccc(OCc2ccccc2)cc1>>COC(=O)[C@H](Cc1ccccc1)Nc1ncnc(-c2ccc(OCc3ccccc3)cc2)c1C=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,c1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20150368254A1,CC(=O)OC(C)=O.C[C@@H](O)[C@H](NC(=O)CN1CC2(CCCN2C(=O)OCc2ccccc2)C1=O)C(N)=O>>CC(=O)N1CCCC12CN(CC(=O)N[C@H](C(N)=O)[C@@H](C)O)C2=O,[Pd],CCOC(C)=O,,,,test
US04818819,COC(=O)C1=CC(I)=CNC1.O=P(Cl)(Cl)Cl>>COC(=O)c1cc(I)cnc1Cl,,ClCCl,,CN(C)C=O,,test
US20150232443A1,CC(C)(C)S(=O)N=C1CCC1.O=S(=O)(CF)c1ccccc1>>CC(C)(C)S(=O)NC1(C(F)S(=O)(=O)c2ccccc2)CCC1,,C1CCOC1,,[Li]CCCC,,test
US04361572,O=C(Nc1ccccc1F)c1cccnc1>>O=C(Nc1ccccc1F)C1=CNCCC1,[Pd],CCO,,[H][H],,test
US03991070,Cc1nnc(Br)n1-c1ccc(Cl)cc1C(=O)c1ccccc1.NN>>Cc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NN2,,CCO,,,,test
US05004741,NC1N=C(c2ccccc2)c2ccccc2N(CC(=O)NCc2ccccc2)C1=O.O=C=Nc1ccc(Cl)cc1>>O=C(CN1C(=O)C(NC(=O)Nc2ccc(Cl)cc2)N=C(c2ccccc2)c2ccccc21)NCc1ccccc1,,C1CCOC1,,,,test
US20110288097A1,CC1(C)CC(=O)N(Cc2ccccc2)C(=O)/C1=N\O>>CC1(C)CCN(Cc2ccccc2)CC1N,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120040949A1,Cn1nc(-c2cccc(-n3ncc4cc(C(C)(C)C)cc(F)c4c3=O)c2CO)cc(Nc2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cn2)c1=O>>Cn1nc(-c2cccc(-n3ncc4cc(C(C)(C)C)cc(F)c4c3=O)c2CO)cc(Nc2ccc(C3CCNCC3)cn2)c1=O,,ClCCl,,,,test
US20090221555A1,CC(C)N1CC2CC(C1)c1cc([N+](=O)[O-])ccc12>>CC(C)N1CC2CC(C1)c1cc(N)ccc12,[Pd],CCO,,[H][H],,test
US20090318437A1,CC(C)c1nn2ccccc2c1C=CCN(C)C.NN>>CC(C)c1nn2ccccc2c1-c1cc[nH]n1,,CCO,,C,C[O-].[Na+],test
US06656957B1,Cc1cccc(C)n1.O=Cc1cccc(Br)c1>>Cc1cccc(C=Cc2cccc(Br)c2)n1,,CC(=O)OC(C)=O,,,,test
US09150556B2,CCCC(CC(=O)O)n1c(=O)n(Cc2cc(Br)cc3c2N(C)C(=O)C3(Br)Br)c2ccccc21>>CCCC(CC(=O)O)n1c(=O)n(Cc2cc(Br)cc3c2N(C)C(=O)C3)c2ccccc21,[Zn],CC(=O)O,,,,test
US20110275611A1,N#Cc1ccc(-c2cc(NCC3CCCCC3)nc(N)n2)cc1F.NN>>Nc1nc(NCC2CCCCC2)cc(-c2ccc3c(N)n[nH]c3c2)n1,,CCO,,O,,test
US06960575B2,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)OC(=O)C(O)[C@@H](N)Cc1ccccc1>>CC(C)OC(=O)C(O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C,,C1CCOC1,,,,test
US05378714,CC1CO1.Fc1ccc2c(C3CCNCC3)n[nH]c2c1>>CC(O)CN1CCC(c2n[nH]c3cc(F)ccc23)CC1,,Cc1ccccc1,,,,test
US20160159809A1,Nc1ncc(-c2nc(NCC(c3ccccc3)c3ccccn3)c3ccccc3n2)cn1.O=CCCl>>c1ccc(C(CNc2nc(-c3cnc4nccn4c3)nc3ccccc23)c2ccccn2)cc1,,CCO,,,,test
US08309542B2,CC(C)(C)OC(=O)N1C[C@H](NC(=O)c2ccc(Cl)s2)C[C@H]1CN=[N+]=[N-]>>CC(C)(C)OC(=O)N1C[C@H](NC(=O)c2ccc(Cl)s2)C[C@H]1CN,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100093703A1,COc1ncc(-n2ccc3cc(N(CC(=O)OC(C)(C)C)S(=O)(=O)c4cc(Cl)cc(Cl)c4)ccc32)c(OC)n1>>O=C(O)CN(c1ccc2c(ccn2-c2c[nH]c(=O)[nH]c2=O)c1)S(=O)(=O)c1cc(Cl)cc(Cl)c1,,CC(=O)O,,Cl,,test
US20140256736A1,COc1ncccc1-c1ccc2onc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c2c1>>Nc1noc2ccc(-c3ccc[nH]c3=O)cc12,,ClCCl,,BrB(Br)Br,,test
US06015905,COC(=O)/C(=C/O)c1ccccc1COc1cccc(C(F)(F)F)n1.COS(=O)(=O)OC>>CO/C=C(/C(=O)OC)c1ccccc1COc1cccc(C(F)(F)F)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120283271A1,CC(C)(C)OC(=O)Cn1ccc(N)n1.O=C(O)[C@H](CC1CCCC1)N1Cc2c(cccc2C(F)(F)F)C1=O>>CC(C)(C)OC(=O)Cn1ccc(NC(=O)[C@H](CC2CCCC2)N2Cc3c(cccc3C(F)(F)F)C2=O)n1,CN(C)C=O,ClCCl,,Cc1cccc(C)n1,O=C(Cl)C(=O)Cl,test
US20090318690A1,CON=Cc1ccsc1CO>>CON=Cc1ccsc1C=O,,ClCCl,c1ccncc1,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20100324068A1,CCOC(=O)Cc1cc(Cl)c(OS(=O)(=O)C(F)(F)F)cc1C.Cc1nc(C)c(-c2ccc(B(O)O)cc2)nc1C(N)=O>>CCOC(=O)Cc1cc(Cl)c(-c2ccc(-c3nc(C(N)=O)c(C)nc3C)cc2)cc1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US20120142625A1,COc1ccc(CNc2ncnc3c2ccn3[C@@H]2C[C@H](CN(C)C3CC(CCc4nc5cc(Br)ccc5[nH]4)C3)[C@H]3OC(C)(C)O[C@H]32)c(OC)c1>>CN(C[C@H]1C[C@@H](n2ccc3c(N)ncnc32)[C@H](O)[C@@H]1O)C1CC(CCc2nc3cc(Br)ccc3[nH]2)C1,,O,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20090275609A1,COC(=O)c1ccc2c(c1)CNCC2.N#Cc1ccc(C=O)cc1>>COC(=O)c1ccc2c(c1)CN(Cc1ccc(C#N)cc1)CC2,,CCOCC,ClCCl,Cl,O=C([O-])O.[Na+],test
US20060183749A1,COCCl.O=c1cc(CO)occ1OCCCCCSc1ccnc2cc(C(F)(F)F)ccc12>>COCOCc1cc(=O)c(OCCCCCSc2ccnc3cc(C(F)(F)F)ccc23)co1,,O,,C1CCOC1,[H-].[Na+],test
US20060178373A1,CC(C)(C)N.COc1cc(-c2cc(=O)c3ccc(OCC4CO4)cc3o2)cc(OC)c1OC>>COc1cc(-c2cc(=O)c3ccc(OCC(O)CNC(C)(C)C)cc3o2)cc(OC)c1OC,,CO,,,,test
US20080119465A1,CC(C)(C)O.O=C(O)Cc1ccc(OCCNC(=O)OCc2ccccc2)cc1>>CC(C)(C)OC(=O)Cc1ccc(OCCNC(=O)OCc2ccccc2)cc1,,ClC(Cl)Cl,,CCN(CC)CC,CCOC(=O)Cl,test
US20130035326A1,CS(=O)(=O)O.O=C(Nc1ccc(-c2ccc(NCCN3CCOCC3)nc2)cc1)Nc1cc(C2(C(F)(F)F)CC2)on1>>CS(=O)(=O)[O-].O=C(Nc1ccc(-c2ccc(NCC[NH+]3CCOCC3)nc2)cc1)Nc1cc(C2(C(F)(F)F)CC2)on1,,CC#N,,,,test
US20120172366A1,O=C(c1cccc(C(F)(F)F)c1Cl)N1CCn2ccnc2C1.O=C1CCC(=O)N1Br>>O=C(c1cccc(C(F)(F)F)c1Cl)N1CCn2c(Br)cnc2C1,,CN(C)C=O,,,,test
US20080090805A1,Nc1cc(C(=O)O)ccc1Sc1cc(F)ccc1C(=O)O>>O=C(O)c1ccc2c(c1)NC(=O)c1ccc(F)cc1S2,,C1CCOC1,,,,test
US04933355,CCOC(=O)C(=O)c1csc(N)n1.O=C=Nc1ccccc1F>>CCOC(=O)C(=O)c1csc(NC(=O)Nc2ccccc2F)n1,,CN(C)C=O,,,,test
US20160102059A1,COc1c(NC(=O)Oc2ccccc2)cc(C(C)(C)C)cc1N(CCO)S(C)(=O)=O.COc1cc(Nc2cc(Oc3ccc(N)c4ccccc34)ccn2)ccc1C(=O)NCCN1CCS(=O)CC1>>COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)cc(N(CCO)S(C)(=O)=O)c4OC)c4ccccc34)ccn2)ccc1C(=O)NCCN1CCS(=O)CC1,,C1CCOC1,,CCN(CC)CC,,test
US05807873,CCOC(=O)/C(CCO)=C(\c1ccc(Cl)cc1)c1ccc(S(=O)(=O)NC(C)(C)C)cc1>>NS(=O)(=O)c1ccc(/C(=C2\CCOC2=O)c2ccc(Cl)cc2)cc1,,O=C(O)C(F)(F)F,,,,test
US20140171314A1,CC(C)(C)OC(=O)NC(C)(C)C(=O)O.NCC(F)(F)F>>CC(C)(C)OC(=O)NC(C)(C)C(=O)NCC(F)(F)F,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20140073658A1,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].CS(=O)(=O)c1ccc(Oc2cc(Sc3ccccn3)cnc2Nc2ccc(C#N)cn2)cc1>>CS(=O)(=O)c1ccc(Oc2cc(Sc3ccccn3)cnc2Nc2ccc(-c3nnn[nH]3)cn2)cc1,,Cc1ccccc1,,,,test
US20040034012A1,O=C(Nc1ccc(C(=O)N2CCc3nc(-c4ccccn4)[nH]c3-c3ccccc32)cc1)c1ccccc1-c1ccccc1>>O=C(Nc1ccc(C(=O)N2CCc3nc(-c4ccccn4)[nH]c3-c3ccccc32)cc1)c1ccccc1-c1ccccc1,,CC#N,,O,,test
US20110046178A1,C=Cc1ccccc1.O=C(O)C=NO.O=C1CCC(=O)N1Cl>>ClC1=NOC(c2ccccc2)C1,,COCCOC,O,O=C([O-])O.[K+],,test
US20040209920A1,CCC(=CCO[C@@H]1CCC[C@H](OCc2nc(-c3ccc(F)cc3)oc2C)C1)C(=O)O>>CCC(CCO[C@@H]1CCC[C@H](OCc2nc(-c3ccc(F)cc3)oc2C)C1)C(=O)O,[Pd],CCOC(C)=O,CO,[H][H],,test
US20100056530A1,COC(=O)CCc1csc(Nc2ncccc2OCc2ccccc2)n1>>O=C(O)CCc1csc(Nc2ncccc2OCc2ccccc2)n1,,C1CCOC1,O,[Li+].[OH-],,test
US20150133457A1,COCCOc1ccc(Nc2nc(Oc3cccc([N+](=O)[O-])c3)c3ccn(COC(=O)C(C)(C)C)c3n2)cc1>>COCCOc1ccc(Nc2nc(Oc3cccc([N+](=O)[O-])c3)c3cc[nH]c3n2)cc1,,CO,,[Na+].[OH-],,test
US20090275047A1,CCOC(=O)C(=O)Cl.Nc1cccc(Oc2ccccc2)c1>>O=C(O)C(=O)Nc1cccc(Oc2ccccc2)c1,,C1CCOC1,O,CCN(CC)CC,[Na+].[OH-],test
US20150307449A1,CN(Cc1cc(-c2ccccc2F)n(S(=O)(=O)c2cccc(O)c2)c1)C(=O)OC(C)(C)C.CNC(=O)C1(CO)CC1>>CNC(=O)C1(COc2cccc(S(=O)(=O)n3cc(CN(C)C(=O)OC(C)(C)C)cc3-c3ccccc3F)c2)CC1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020055631A1,O=S(=O)(N(c1ccccn1)S(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1ccc2cccc(O)c2n1>>O=S(=O)(Oc1cccc2ccc(O)nc12)C(F)(F)F,,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20110015157A1,O=C1OC(CCO)(c2ccccc2F)CCN1c1cccc(-c2ccc(F)cc2)n1.OO>>O=C1OC(CCO)(c2ccccc2F)CCN1c1cccc(-c2ccc(F)cc2)[n+]1[O-],,CC(=O)O,,,,test
US20050032871A1,CN(C)S(=O)(=O)c1ccc2c(c1)CC(=O)N2.Cc1ccc(S(=O)(=O)c2c(C)[nH]c(C=O)c2CCC(=O)O)cc1>>Cc1ccc(S(=O)(=O)c2c(C)[nH]c(/C=C3\C(=O)Nc4ccc(S(=O)(=O)N(C)C)cc43)c2CCC(=O)O)cc1,,CCO,,C1CCNCC1,,test
US04067725,CCOC(=O)C(C)Oc1ccc(Cl)nc1Cl>>CC(Oc1ccc(Cl)nc1Cl)C(=O)O,,[Na+],[OH-],Cl,,test
US05164388,COC(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)OCc1ccccc1>>COC(=O)CNC(=O)[C@H](N)Cc1ccccc1,[Pd],CO,,,,test
US20020053659A1,CN(C)C=O.Fc1cc(F)cc(Br)c1>>O=Cc1cc(F)cc(F)c1,,C1CCOC1,,Cl,[Mg],test
US20130172292A1,CSc1nc2cccnc2[nH]1.O=S(=O)(OCC(F)F)C(F)(F)F>>CSc1nc2cccnc2n1CC(F)F,,CN(C)C=O,,O,,test
US20020028807A1,C=CCc1cnc2c(c1)C(=O)N(C)c1ccc(Cl)nc1N2CC.O=O>>CCN1c2ncc(CCO)cc2C(=O)N(C)c2ccc(Cl)nc21,,CO,ClCCl,[BH4-].[Na+],[Cl-].[NH4+],test
US20120088748A1,CC(C)(C)OC(=O)N1CCOC(CO)C(c2ccc(Cl)c(Cl)c2)C1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)N1CCOC(COS(C)(=O)=O)C(c2ccc(Cl)c(Cl)c2)C1,,C1CCOC1,,CCN(CC)CC,O,test
US04444775,COC(=O)CCCCc1cccnc1C#N.Cl>>COC(=O)CCCCc1cccnc1CN.Cl,[Pd],CO,,,,test
US20150239921A1,CC(=O)c1c[nH]c2cc(Br)ccc12.CC(C)(C)OC(=O)CBr>>CC(=O)c1cn(CC(=O)OC(C)(C)C)c2cc(Br)ccc12,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110034450A1,Cc1ccc(C(CCC(F)(F)F)C(=O)OC(C)(C)C)cc1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)C(CCC(F)(F)F)c1ccc(CBr)cc1,,ClC(Cl)(Cl)Cl,,,,test
US20120245171A1,CC1(C)CC(C)(C)OB(c2cc(N)c3cnn(S(=O)(=O)c4ccccc4)c3c2)O1.O=S(=O)(Nc1cc(Br)cnc1Cl)c1ccccc1>>Nc1cc(-c2cnc(Cl)c(NS(=O)(=O)c3ccccc3)c2)cc2c1cnn2S(=O)(=O)c1ccccc1,,O,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20040058978A1,CCOC(=C1C(=O)N(C(C)=O)c2ccccc21)c1ccccc1.COc1ccccc1N>>COc1ccccc1N/C(=C1\C(=O)Nc2ccccc21)c1ccccc1,,CN(C)C=O,CO,[Na+].[OH-],,test
US20120135990A1,CC(=O)OC(C)=O.CC(C(=O)NC(C(=O)N1CCC2NCC(Oc3ccc(F)c(F)c3)C21)C(C)(C)C)N(C)C(=O)OCc1ccccc1>>CC(=O)N1CC(Oc2ccc(F)c(F)c2)C2C1CCN2C(=O)C(NC(=O)C(C)N(C)C(=O)OCc1ccccc1)C(C)(C)C,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US04963590,CC(=O)Oc1cc(C(=O)O)cc([N+](=O)[O-])c1OC(C)=O.NCc1ccccc1>>CC(=O)Oc1cc(C(=O)NCc2ccccc2)cc([N+](=O)[O-])c1OC(C)=O,,ClCCl,,Cc1cccc(C)n1,,test
US05506190,CCN.O=C1C2=C(CCCC2)C(=O)N1c1cc(OC2CCCC2)c(Cl)cc1F>>CCNC(=O)C1=C(C(=O)Nc2cc(OC3CCCC3)c(Cl)cc2F)CCCC1,,c1ccccc1,,,,test
US20070197559A1,CCOC(OCC)OCC.Nc1c(Cl)ncnc1Nc1ccccc1Cl>>Clc1ccccc1-n1cnc2c(Cl)ncnc21,,CC(=O)OC(C)=O,,,,test
US20050187390A1,C1CCNC1.CC(=O)c1cc(C(=O)O)ccc1O>>CC(=O)c1cc(C(=O)N2CCCC2)ccc1O,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20080214582A1,Nc1ccc(-n2cnc3c(N)ncnc32)cc1.O=C=Nc1cccc(C(F)(F)F)c1>>Nc1ncnc2c1ncn2-c1ccc(NC(=O)Nc2cccc(C(F)(F)F)c2)cc1,,ClCCl,,CCN(CC)CC,,test
US20070213371A1,COC(c1ccc(C(F)(F)F)cc1C=O)C1CCCCC1.NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>COC(c1ccc(C(F)(F)F)cc1CNCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCCC1,,CCO,,[BH4-].[Na+],,test
US05840732,CCOC(=O)C=C1SC(=O)N(CCCCSc2cccc3nccn23)C1=O.Cl>>CCOC(=O)C=C1SC(=O)N(CCCCSc2cccc3nccn23)C1=O.Cl,,CO,,,,test
US20060287341A1,Clc1ccc(-c2cc(Cl)ncn2)cc1.NN>>NNc1cc(-c2ccc(Cl)cc2)ncn1,,C1CCOC1,,,,test
US20150252030A1,COC(=O)CBr.Cc1cc(C)c(O)c(Br)c1>>COC(=O)COc1c(C)cc(C)cc1Br,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US07462204B2,CC(C)(C)c1nn(Cc2ccncc2)c(N)c1OC(N)=O.COS(=O)(=O)OC>>CN1C=C[CH2+]=CC1Cn1nc(C(C)(C)C)c(OC(N)=O)c1N.COS(=O)(=O)[O-],,CCOC(C)=O,,,,test
US20100041041A1,CC(C)[C@@H](OC(=O)C1CC2CC[C@]1(C)C2(C)C)c1ccc(I)cc1[N+](=O)[O-]>>CC(C)[C@@H](O)c1ccc(I)cc1[N+](=O)[O-],,CO,,O=C([O-])[O-].[K+].[K+],,test
US20120232067A1,CC(C)(C)[Si](C)(C)OCCCNc1cc(Br)ccc1[N+](=O)[O-]>>CC(C)(C)[Si](C)(C)OCCCNc1cc(Br)ccc1N,[Fe],O,,,,test
US20040077704A1,COC(=O)COc1cc2c(c3c1c(C(=O)C(N)=O)c(C)n3Cc1ccccc1Br)CCC2.OB(O)c1ccccc1>>COC(=O)COc1cc2c(c3c1c(C(=O)C(N)=O)c(C)n3Cc1ccccc1-c1ccccc1)CCC2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150105366A1,Cc1nc2ccc(C(O)(c3cnnn3C)C3CN(C(=O)OC(C)(C)C)C3)cc2c(Cl)c1Cc1ccc(C(F)(F)F)cc1>>CC(=O)N1CC(C(O)(c2ccc3nc(C)c(Cc4ccc(C(F)(F)F)cc4)c(Cl)c3c2)c2cnnn2C)C1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20110118230A1,BrCc1ccc(Br)cc1.CN(C)C1CCNCC1>>CN(C)C1CCN(Cc2ccc(Br)cc2)CC1,,C1CCOC1,O,CCN(CC)CC,,test
US20100137394A1,CNC(=O)Nc1ccc(C2=NN(C(=O)Cc3cc(OC)c(OC)cc3Br)CC2)cc1.OB(O)c1ccccc1>>CNC(=O)Nc1ccc(C2=NN(C(=O)Cc3cc(OC)c(OC)cc3-c3ccccc3)CC2)cc1,,C1COCCO1,CO,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20100099561A1,BrCCBr.Cc1c(C(F)(F)F)[nH]c(=O)[nH]c1=O>>Cc1c(C(F)(F)F)nc2n(c1=O)CCO2,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100210617A1,C[C@H](NC(=O)C[C@H](c1ccc(-c2cn[nH]c2)cc1)c1ccc(Cl)c(Cl)c1)c1ccccc1>>NC(=O)C[C@H](c1ccc(-c2cn[nH]c2)cc1)c1ccc(Cl)c(Cl)c1,,O=S(=O)(O)O,,O,[Na+].[OH-],test
US20120316161A1,CCCC(C(=O)OC)c1c(C)nc2c(-c3ccc(C)cc3)c(C(C)(C)C)nn2c1-c1ccc(C)cc1>>CCCC(C(=O)O)c1c(C)nc2c(-c3ccc(C)cc3)c(C(C)(C)C)nn2c1-c1ccc(C)cc1,,CO,,[Na+].[OH-],,test
US20100249094A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)O)ccc3C)c(F)c12.Cc1ccnc(C2(N)CC2)n1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NC4(c5nccc(C)n5)CC4)ccc3C)c(F)c12,,CN(C)C=O,,CCN(CC)CC,,test
US20140142083A1,CI.COC(=O)c1cc(Br)cc(NC2CCN(C)CC2)c1C>>COC(=O)c1cc(Br)cc(N(C)C2CCN(C)CC2)c1C,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130225527A1,CP(C)(=O)c1ccc(Nc2ncnc(Cl)n2)cc1.NCCc1c[nH]c2ccccc12>>CP(C)(=O)c1ccc(Nc2ncnc(NCCc3c[nH]c4ccccc34)n2)cc1,,CCO,,CCN(CC)CC,,test
US20080262020A1,COc1ccc(-c2cc3c4cc(-c5ccn[nH]5)ccc4n(C)c3n(C)c2=O)c(Cl)c1>>Cn1c(=O)c(-c2ccc(O)cc2Cl)cc2c3cc(-c4ccn[nH]4)ccc3n(C)c21,,ClCCl,,BrB(Br)Br,O,test
US20100087480A1,COC(=O)c1ccc2nc(C(C)(C)C(F)(F)F)ccc2c1>>CC(C)(c1ccc2cc(C(=O)O)ccc2n1)C(F)(F)F,,C1CCOC1,,CO,[Na+].[OH-],test
US04665181,O=c1[nH]ncc2cc(C=Cc3ccccc3)ccc12>>O=c1[nH]ncc2cc(CCc3ccccc3)ccc12,[Pd],CN(C)C=O,,,,test
US20130005710A1,COc1ccc(N2CCN(c3ccc(OC)nc3Br)CC2)cc1.Cc1ccc(B(O)O)cc1>>COc1ccc(N2CCN(c3ccc(OC)nc3-c3ccc(C)cc3)CC2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,O,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US05126344,CCOC(=O)/C=C(/C)Nc1cccnc1>>Cc1cc(=O)c2ncccc2[nH]1,,c1ccc(Oc2ccccc2)cc1,,,,test
US20110065739A1,CC(C)Oc1cccc(CCO)c1>>CC(C)Oc1cccc(CC=O)c1,,ClC(Cl)Cl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05041442,C=O.CNC.c1ccc(CCc2nccn3cccc23)cc1>>CCc1cccc(-c2nccn3c(CN(C)C)ccc23)c1,,CC#N,,Cl,[Na+].[OH-],test
US20130150343A1,Nc1cc(F)cc(N2CCOCC2)c1.O=C(Cl)OCC(Cl)(Cl)Cl>>O=C(Nc1cc(F)cc(N2CCOCC2)c1)OCC(Cl)(Cl)Cl,,C1CCOC1,,CCN(CC)CC,,test
US20130059834A1,Cc1ccc2c(-c3cnc4c(n3)c(C(=O)NC(C)(C)CO[Si](C)(C)C(C)(C)C)cn4C(c3ccccc3)(c3ccccc3)c3ccccc3)nn(CCCN3CCOCC3)c2c1.Cl>>Cc1ccc2c(-c3cnc4[nH]cc(C(=O)NC(C)(C)CO)c4n3)nn(CCCN3CCOCC3)c2c1.Cl,,C1COCCO1,,,,test
US20020052498A1,CCCCCCCCCCCCCCCCCCBr.CN(C)CCCNC(=O)CCc1ccccc1O>>CCCCCCCCCCCCCCCCCCOc1ccccc1CCC(=O)NCCCN(C)C,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150111925A1,CC(=O)O.CCOC(=O)C(=O)CC(=O)C1CC1.CCOC(=O)c1cc(C2CC2)n(-c2ccc(Br)cn2)n1.NNc1ccc(Br)cn1>>Cn1nc(-c2cc(C3CC3)n(-c3ccc(Br)cn3)n2)oc1=O,,CC(=O)O,,,,test
US20020169336A1,COC(=O)[C@@H](N)Cc1cc(OC)c(-c2ccccc2)c(OC)c1.O=C1CC(=O)C12CCOCC2>>COC(=O)[C@H](Cc1cc(OC)c(-c2ccccc2)c(OC)c1)NC1=CC(=O)C12CCOCC2,,ClCCl,,,,test
US20100305325A1,COc1ccc(CCNC(=O)CCc2ccc(C(F)(F)F)cc2)cc1OC.CS(=O)(=O)O>>COc1cc2c(cc1OC)C(CCc1ccc(C(F)(F)F)cc1)(CS(=O)(=O)O)NCC2,,Cc1ccccc1,O,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US20140179666A1,C[C@@H]1CN[C@@H](CN2CCCC2=O)CN1C(=O)OC(C)(C)C.O=C(CBr)OCc1ccccc1>>C[C@@H]1CN(CC(=O)OCc2ccccc2)[C@@H](CN2CCCC2=O)CN1C(=O)OC(C)(C)C,,CC#N,ClC(Cl)Cl,O=C([O-])[O-].[K+].[K+],,test
US20050197346A1,Cc1nc2cc(OCC(O)CN3CCN(CCN)CC3)ccc2s1.O=S(=O)(Cl)c1ccccc1>>Cc1nc2cc(OC[C@H](O)CN3CCN(CCNS(=O)(=O)c4ccccc4)CC3)ccc2s1,,COCCOC,,,,test
US20110245224A1,CC(=O)c1cc(C=O)c(N2C[C@H](C)O[C@H](C)C2)c(F)c1F.O=C1CC(=O)NC(=O)N1>>CC(=O)c1cc2c(c(F)c1F)N1C[C@@H](C)O[C@@H](C)[C@@H]1C1(C2)C(=O)NC(=O)NC1=O,,CC(C)O,,,,test
US04076821,Cc1ccc(S(=O)(=O)OC2CCC(c3ccccc3)(c3ccccc3)CC2)cc1.O=c1[nH]c2ccccc2n1C1CCNCC1>>O=c1[nH]c2ccccc2n1C1CCN(C2CCC(c3ccccc3)(c3ccccc3)CC2)CC1,,CN(C)C=O,,[I-].[K+],,test
US20120252780A1,BrCCBr.Nc1nc(Cl)ncc1O>>Clc1ncc2c(n1)NCCO2,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20040072876A1,N.O=C(O)c1ccc(-c2csc(-c3cnccc3C(F)(F)F)n2)cc1>>NC(=O)c1ccc(-c2csc(-c3cnccc3C(F)(F)F)n2)cc1,CN(C)C=O,C1CCOC1,,O=C(Cl)C(=O)Cl,,test
US20090306126A1,Cc1nc2c(ccn2C(=O)OC(C)(C)C)cc1-c1cnc(Cl)c(N)c1.O=S(=O)(Cl)c1ccccc1>>Cc1nc2[nH]ccc2cc1-c1cnc(Cl)c(NS(=O)(=O)c2ccccc2)c1,,c1ccncc1,,,,test
US20160145268A1,BrBr.Cc1ccc([N+](=O)[O-])c(O)n1>>Cc1nc(O)c([N+](=O)[O-])cc1Br,,CO,,C[O-].[Na+],,test
US20150073019A1,CN(C)C=C1C(=O)N(c2nc3c(Cl)cccc3s2)N=C1c1ccccc1.N>>NC=C1C(=O)N(c2nc3c(Cl)cccc3s2)N=C1c1ccccc1,,CO,N,,,test
US05264437,ClCc1ccncc1.O=C1NCc2cccnc2N1c1cccc(Cl)c1>>O=C1N(Cc2ccncc2)Cc2cccnc2N1c1cccc(Cl)c1,,C1CCOC1,,Cl,[H-].[Na+],test
US04568766,CC(C)Br.O=S(=O)(c1ccc(O)cc1)c1ccc(O)cc1>>CC(C)Oc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040072827A1,CN(C)CCCNC(=S)Nc1ccccc1.O=C(CBr)c1ccc(Br)cc1>>CN(C)CCCn1c(-c2ccc(Br)cc2)csc1=Nc1ccccc1,,CCO,,,,test
US20080269196A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)NCc1ccc(C#N)cc1>>CC(C)N(Cc1ccc(C#N)cc1)C(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US06310056B1,C=CCOC(=O)C1=C(c2ncn3ccsc23)[C@H](C)[C@@H]2[C@@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)C(=O)N12>>C=CCOC(=O)C1=C(c2ncn3ccsc23)[C@H](C)[C@@H]2[C@@H]([C@@H](C)O)C(=O)N12,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(CN4CCN(C(=O)OC(C)(C)C)C[C@@H]4C)cnc3F)n2)cc1.CS(=O)(=O)Cl>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(CN4CCN(S(C)(=O)=O)C[C@@H]4C)cnc3F)n2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100160320A1,CC(C)(C)c1cccc(NC(=O)[C@H]2CCCN[C@H]2C2CCCC2)c1.Cc1ccccc1C(=O)Cl>>Cc1ccccc1C(=O)N1CCC[C@H](C(=O)Nc2cccc(C(C)(C)C)c2)[C@@H]1C1CCCC1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20140350002A1,Cn1c(=O)n(CC(C)(C)C)c2ccc(C34CC5CN(C(=O)OC(C)(C)C)CC5C3C4(F)F)nc21>>Cn1c(=O)n(CC(C)(C)C)c2ccc(C34CC5CNCC5C3C4(F)F)nc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140206680A1,COc1ccc(CN)c(OC)c1.O=C1OC(O)c2c(F)c(Cl)nc(Cl)c21>>COc1ccc(C/N=C/c2c(F)c(Cl)nc(Cl)c2C(=O)O)c(OC)c1,,CO,,,,test
US05595976,C=C(C)[C@@]1(O)[C@H](OC)[C@H](OC)CO[C@]1(O)CI>>C=C(C)[C@@]1(O)[C@H](OC)[C@H](OC)CO[C@]12CO2,O=[Ag-],C1COCCO1,,,,test
US20040110762A1,C1CCOC1.CC#N.CCOC(=O)c1cc2cc(OC)c(OCCCl)cc2cc1/N=C/N(C)C.CCOC(=O)c1cc2cc(OCCCl)c(OC)cc2cc1/N=C/N(C)C>>COc1cc2cc3[nH]cc(C#N)c(=O)c3cc2cc1OCCCl.N#Cc1cnc2ccccc2c1,,C1CCOC1,,[Li]CCCC,,test
US20140288040A1,CC[C@H](Nc1cccc2c1CN(C(=O)OC(C)(C)C)C2)c1ccc(F)c(Oc2ccccc2)c1F.Cl>>CC[C@H](Nc1cccc2c1CNC2)c1ccc(F)c(Oc2ccccc2)c1F.Cl,,CCOC(C)=O,,,,test
US20160060258A1,Cc1cc(Nc2ncc3c(=O)n(-c4ccccc4Cl)ccc3n2)ccc1N1CCN(C(=O)OC(C)(C)C)CC1>>Cc1cc(Nc2ncc3c(=O)n(-c4ccccc4Cl)ccc3n2)ccc1N1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120329780A1,COc1ccc(Cn2cc3nc(-c4cccc(SC)c4)nc(Cl)c3n2)cc1.Nc1ccc2c(c1)NC(=O)CC2>>CSc1cccc(-c2nc(Nc3ccc4c(c3)NC(=O)CC4)c3[nH]ncc3n2)c1,C1COCCO1,CO,,Cl,,test
US20110288067A1,CC(C)(C)OC(=O)N[C@@H](CC#N)C(C)(C)C.Cl>>CC(C)(C)[C@@H](N)CC#N.Cl,,C1COCCO1,,,,test
US20090131458A1,CS(=O)(=O)Cl.OCCC1CCCO1>>CS(=O)(=O)OCCC1CCCO1,,ClCCl,,CCN(CC)CC,,test
US20110301122A1,Cc1cc(-c2nc(-c3ccc(CN(C(C)C)C(C)C)cc3)no2)n[nH]1.ClCc1ccc(Cl)nc1>>Cc1cc(-c2nc(-c3ccc(CN(C(C)C)C(C)C)cc3)no2)nn1Cc1ccc(Cl)nc1,,C1CCOC1,O,CCOC(C)=O,CC(C)(C)[O-].[K+],test
US20040138251A1,COc1cc(N)c(Cl)cc1Cl.N#Cc1cnc2sc(I)cc2c1Cl>>COc1cc(Nc2c(C#N)cnc3sc(I)cc23)c(Cl)cc1Cl,,C1CCOC1,,[H-].[Na+],,test
US20110034433A1,CC1=C(C#N)[C@@H](c2ccc(C#N)cc2S(C)(=O)=O)N(C(=O)Oc2ccc([N+](=O)[O-])cc2)C(=O)N1c1cccc(C(F)(F)F)c1.NC1CCS(=O)(=O)C1>>CC1=C(C#N)[C@@H](c2ccc(C#N)cc2S(C)(=O)=O)N(C(=O)NC2CCS(=O)(=O)C2)C(=O)N1c1cccc(C(F)(F)F)c1,,CC#N,,,,test
US20040259884A1,BrC(Br)(Br)Br.CCOc1cc(C(F)(F)F)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCC(CO)CC1>>CCOc1cc(C(F)(F)F)ccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)N1CCC(CBr)CC1,,ClCCl,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20120053173A1,Cc1c(C(=O)C(C)C)oc2ccc(Br)cc12>>Cc1c(C(O)C(C)C)oc2ccc(Br)cc12,,C1CCOC1,CO,[BH4-].[Na+],,test
US05834494,CCCSc1cc2c(cc1Br)N(C(C)=O)CC2.CI>>CSc1cc2c(cc1Br)N(C(C)=O)CC2,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05506240,Cc1ccc2oc(-c3ccccc3-c3nnn[nH]3)c(Br)c2c1.ClC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cc1ccc2oc(-c3ccccc3-c3nnnn3C(c3ccccc3)(c3ccccc3)c3ccccc3)c(Br)c2c1,,ClCCl,,CCN(CC)CC,,test
US20150166543A1,CCCCc1cc(N)cc(O)c1Cc1c[nH]c2ccccc12.CN1CCN(CCN)CC1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCCCc1cc(NC(=O)NCCN2CCN(C)CC2)cc(O)c1Cc1c[nH]c2ccccc12,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US06008229,COC(=O)CCc1ccc(C(=O)NCc2ccccn2)cc1>>O=C(O)CCc1ccc(C(=O)NCc2ccccn2)cc1,,CO,,[Na+].[OH-],,test
US20030199440A1,BrCC1CCCCC1.CC(C)(C)OC(=O)CNS(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1>>CC(C)(C)OC(=O)CN(CC1CCCCC1)S(=O)(=O)c1ccc2c(Cl)cnc(Cl)c2c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20160016908A1,CC(=O)N1c2ccc(N3CCN(C(=O)OC(C)(C)C)[C@@H](C)C3)cc2[C@H](Nc2ccc(F)cn2)[C@@H](C)[C@@H]1C1CC1>>CC(=O)N1c2ccc(N3CCN[C@@H](C)C3)cc2[C@H](Nc2ccc(F)cn2)[C@@H](C)[C@@H]1C1CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04526932,C=CN1CCCC1=O.Cl[Sn](c1ccccc1)(c1ccccc1)c1ccccc1>>C=CN1CCCC1=O.Cl[Sn](c1ccccc1)(c1ccccc1)c1ccccc1,,Cc1ccccc1C,,,,test
US20100087495A1,Cc1cc(-c2noc(-c3ccc(OC(C)C)cc3)n2)cc(C)c1OCC(O)CN.O=C(O)CO>>Cc1cc(-c2noc(-c3ccc(OC(C)C)cc3)n2)cc(C)c1OCC(O)CNC(=O)CO,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20140128372A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOCC(O)CN>>CCOCC(O)CNC(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,Cl,test
US20050197373A1,C=CC=CCCNCc1ccccc1.CCOC(=O)C=CCBr>>CCOC(=O)C1CC=CC2CCN(Cc3ccccc3)CC21,,CC#N,,CCN(CC)CC,O,test
US06107458,CCCCCOc1ccc(C(=O)CC(=O)c2ccc(C(=O)OC)cc2)cc1.NO>>CCCCCOc1ccc(-c2cc(-c3ccc(C(=O)OC)cc3)no2)cc1,,CCOC(C)=O,CO,Cl,,test
US20090118312A1,COc1ccc(CN2CCCCCC=CC3CC3(C(=O)NS(=O)(=O)C3CC3)NC(=O)C3CC(Oc4nc(-c5ccc(F)cc5)nc5c(C)c(OC)ccc45)CN3C2=O)cc1>>COc1ccc2c(OC3CC4C(=O)NC5(C(=O)NS(=O)(=O)C6CC6)CC5C=CCCCCCNC(=O)N4C3)nc(-c3ccc(F)cc3)nc2c1C,,ClCCl,O=C(O)C(F)(F)F,,,test
US20120289500A1,O=c1[nH]nc(Cl)c2ccccc12.Sc1ccccc1>>O=c1[nH]nc(Sc2ccccc2)c2ccccc12,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100048636A1,CC(C)(C)OC(=O)N1CCC[C@@H](C(O)c2cccc(F)c2F)C1.CCOC(=O)CBr>>CCOC(=O)COC(c1cccc(F)c1F)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20080004302A1,COc1cc(CO)c(F)cn1>>COc1cc(C=O)c(F)cn1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20090286791A1,C1COCCO1.CCOC(=O)/C=C(\C)N.Cc1ccccc1>>CCOC(=O)c1c(C)cc(=O)[nH]c1C,,C1COCCO1,Cc1ccccc1,Cl,,test
US20120065195A1,CN1C(=O)[C@]2(CC(C)(C)Cc3ccc(Br)cc32)N=C1N.OB(O)c1cncnc1>>CN1C(=O)[C@]2(CC(C)(C)Cc3ccc(-c4cncnc4)cc32)N=C1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US04625047,C=C(C(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl)C1CCCC1.CCOC(=O)CC(C)=O>>O=C(O)COc1ccc(C2=CC(=O)CCC2C2CCCC2)c(Cl)c1Cl,,CCO,,C[O-].[Na+],,test
US20110034507A1,CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CO.Oc1ccc2[nH]ccc2c1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2[nH]ccc2c1,,ClCCl,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20020035118A1,O=C(CCNC(=O)OCc1ccccc1)NCCS(=O)(=O)O>>NCCC(=O)NCCS(=O)(=O)O,,CC(=O)O,,Br,,test
US20100298336A1,BrCc1cn2ccccc2n1.Cc1cc(O)nc(S)n1>>Cc1cc(O)nc(SCc2cn3ccccc3n2)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070010537A1,Nc1cc(C(=O)N2CCCc3ccccc32)ccc1C(F)(F)F.O=C(Cl)c1ccccc1[N+](=O)[O-]>>O=C(Nc1cc(C(=O)N2CCCc3ccccc32)ccc1C(F)(F)F)c1ccccc1[N+](=O)[O-],,C1CCOC1,CCOC(C)=O,O=C([O-])O.[Na+],,test
US20140303127A1,CC(C)(C)[Si](C)(C)OCCCBr.O=Cc1ccc2[nH]c(=O)oc2c1>>CC(C)(C)[Si](C)(C)OCCCn1c(=O)oc2cc(C=O)ccc21,,CN(C)C=O,,CCOCC,O=C([O-])[O-].[K+].[K+],test
US20050020684A1,CC(C)(C)[Si](C)(C)OCCO.CCOC(=O)[C@H](Cc1ccc(OCCCOc2ccc(C(=O)c3ccc(O)cc3)cc2)cc1)OC>>CCOC(=O)[C@H](Cc1ccc(OCCCOc2ccc(C(=O)c3ccc(OCCO[Si](C)(C)C(C)(C)C)cc3)cc2)cc1)OC,,Cc1ccccc1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04992459,COC(CN)OC.COc1ccc(C=O)cc1F>>COc1ccc(CNCC(OC)OC)cc1F,,CCO,,[BH4-].[Na+],,test
US20110190272A1,COc1cc2nnc(C(N)=O)c(Nc3ccc(C)cc3F)c2cc1N1CCNCC1.CS(=O)(=O)CCBr>>COc1cc2nnc(C(N)=O)c(Nc3ccc(C)cc3F)c2cc1N1CCN(CCS(C)(=O)=O)CC1,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20070219235A1,CS(=O)(=O)OCCNCCc1cc(N)c([N+](=O)[O-])cc1C(=O)Nc1ccc2cnn(S(C)(=O)=O)c2c1>>CCN1CCN(c2ccc3cnn(S(C)(=O)=O)c3c2)C(=O)c2cc([N+](=O)[O-])c(N)cc21,,C1CCOC1,,[H-].[Na+],,test
US05767160,Nc1nc(=O)c2ncn([C@@H]3O[C@@H]4COP(=O)(O)O[C@H]4[C@H]3O)c2[nH]1>>Nc1nc(=O)c2ncn(C3OC4COP(=O)(O)OC4C3O)c2[nH]1,,Cl,,,,test
US20070078121A1,N#CCC(=O)C1CCCC1.NNc1ccc2c(c1)CCC(=O)N2>>Nc1cc(C2CCCC2)nn1-c1ccc2c(c1)CCC(=O)N2,,CCO,,,,test
US20130035318A1,C=C(C)[C@@H]1CC[C@]2(NC(=O)C3(NC(=O)OC(C)(C)C)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12>>C=C(C)[C@@H]1CC[C@]2(NC(=O)C3(NC(=O)OC(C)(C)C)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,C1CCOC1,O,[Li+].[OH-],,test
US20120059182A1,CC(=O)OC=O.CC(C)(C)Nc1ccccc1>>CC(C)(C)N(C=O)c1ccccc1,,C1CCOC1,,[Na+].[OH-],,test
US20100168243A1,CCc1cccc(-c2c(Cl)cccc2N(CCCCOC)CCN(C)C(=O)OC(C)(C)C)c1>>CCc1cccc(-c2c(Cl)cccc2N(CCCCOC)CCNC)c1,,C1COCCO1,CC#N,Cl,,test
US06153609,COc1ccc(S(=O)(=O)N(CCC(=O)N2CCC(NCC(=O)OC(C)(C)C)CC2)C(C(=O)OCc2ccccc2)C2CCCCC2)cc1>>COc1ccc(S(=O)(=O)N(CCC(=O)N2CCC(NCC(=O)OC(C)(C)C)CC2)C(C(=O)O)C2CCCCC2)cc1,[Pd],CCO,,[H][H],,test
US20140350019A1,CCOC(=O)CBr.Oc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2Cl)c1F>>CCOC(=O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2Cl)c1F,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20090186879A1,CCC(CC)c1cccc2c1[nH]c(=O)n2C(=O)OC(C)(C)C.CCOC(=O)CCCBr>>CCOC(=O)CCCn1c(=O)n(C(=O)OC(C)(C)C)c2cccc(C(CC)CC)c21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05332717,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.COc1cc(OC)nc(Oc2cccc3c2C(=O)OC3O)n1>>CCOC(=O)CC1OC(=O)c2c(Oc3nc(OC)cc(OC)n3)cccc21,,C1CCOC1,,,,test
US20040106653A1,CCOC(=O)c1ccc(S(=O)(=O)c2ccc(CCCN)cc2)cc1C.Clc1cccc([C@@H]2CO2)c1>>CCOC(=O)c1ccc(S(=O)(=O)c2ccc(CCCNC[C@H](O)c3cccc(Cl)c3)cc2)cc1C,,CCO,,,,test
US20140088150A1,II.OCC1CC=C(c2ccc3c(nnn3CC3CC3)c2Cl)CC1>>Clc1c(C2=CCC(CI)CC2)ccc2c1nnn2CC1CC1,,C1CCOC1,,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160229814A1,NCc1ccccc1.O=C=NCc1ccccc1>>O=C(NCc1ccccc1)NCc1ccccc1,,C1CCOC1,,,,test
US20070191405A1,C1CCNC1.O=C(Cl)c1cccc(Br)c1>>O=C(c1cccc(Br)c1)N1CCCC1,,ClCCl,,,,test
US20100048727A1,CCCCCCOc1ccc(C=O)cc1.CCOC(=O)/C=C/CP(=O)(OCC)OCC>>CCCCCCOc1ccc(/C=C/C=C/C(=O)OCC)cc1,,C1CCOC1,,[Li+].[OH-],,test
US20050020684A1,CO[C@@H](Cc1ccc(C#CCCCOc2ccc(-c3ccccc3)cc2)cc1)C(=O)O>>CO[C@@H](Cc1ccc(CCCCCOc2ccc(-c3ccccc3)cc2)cc1)C(=O)O,[Pd],CO,,[H][H],,test
US06358973B1,COc1cccc(C(CN)CCCCCCc2ccccc2)c1.O=C(O)Cc1c(Cl)cncc1Cl>>COc1cccc(C(CCCCCCc2ccccc2)CNC(=O)Cc2c(Cl)cncc2Cl)c1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20120149676A1,C#CCNC.CNc1cc(Cl)c(C(=O)N[C@@H]2CC[C@@H](C(F)(F)F)CC2)cc1[N+](=O)[O-]>>C#CCN(C)c1cc(NC)c([N+](=O)[O-])cc1C(=O)N[C@@H]1CC[C@@H](C(F)(F)F)CC1,,O,,CC#N,,test
US20140213578A1,Cc1ccc(S(=O)(=O)Cl)cc1.NCCN1c2ccccc2Sc2ccc(Cl)cc21>>Cc1ccc(S(=O)(=O)NCCN2c3ccccc3Sc3ccc(Cl)cc32)cc1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20080312451A1,BrCc1ccc(Br)cc1.CCCc1nc(C(C)(C)O)c(C(=O)OCC)[nH]1>>CCCc1nc(C(C)(C)O)c(C(=O)OCC)n1Cc1ccc(Br)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20050014812A1,CCOC(=O)CCCOc1cc(C)c(N)c(N)c1.CCOC(OCC)(OCC)OCC>>CCOC(=O)CCCOc1cc(C)c2nc(OCC)[nH]c2c1,,CC(=O)O,,,,test
US20020156081A1,COc1cc(-c2nn(C3CCNC3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C.Cc1n[nH]cc1C=O>>COc1cc(-c2nn(C3CCN(Cc4c[nH]nc4C)C3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C,,CC(Cl)Cl,,[Na+].[OH-],,test
US20080292608A1,Cc1cc(OCc2ccccc2)ccc1O[Si](C)(C)C(C)(C)C>>Cc1cc(OCc2ccccc2)ccc1O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20130345444A1,CC[C@@H](N)c1ccccc1.O=C(O)CC1COc2cc(O)ccc21>>CC[C@@H](N)c1ccccc1.O=C(O)C[C@@H]1COc2cc(O)ccc21,,CO,,,,test
US20040209865A1,CCO/C=C/C(=O)Cl.Nc1ccc(Br)cc1>>CCO/C=C/C(=O)Nc1ccc(Br)cc1,,c1ccncc1,,O,,test
US04636521,CS(=O)(=O)Cl.NCc1ccc2[nH]cc(CCNC(=O)OCc3ccccc3)c2c1>>CS(=O)(=O)NCc1ccc2[nH]cc(CCNC(=O)OCc3ccccc3)c2c1,,c1ccncc1,,,,test
US20100029710A1,CCC(=O)Cl.CCc1nc2c(C)cc(CC(=O)NN)nc2n1[C@H]1CCc2cc(Br)ccc21>>CCC(=O)NNC(=O)Cc1cc(C)c2nc(CC)n([C@H]3CCc4cc(Br)ccc43)c2n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120295884A1,CN1CCN(Cc2cc(Cl)c(F)c(CNC(=O)OC(C)(C)C)c2)CC1>>CN1CCN(Cc2cc(Cl)c(F)c(CN)c2)CC1,,C1COCCO1,,Cl,,test
US20150299179A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)CN[C@@H]1CCCc2c(-c3nnc(-c4ccc(OC(C)C)c(C#N)c4)s3)cccc21>>COC(=O)CN(C(=O)OC(C)(C)C)[C@@H]1CCCc2c(-c3nnc(-c4ccc(OC(C)C)c(C#N)c4)s3)cccc21,,ClCCl,,,,test
US06359145B1,CS(=O)(=O)Cl.C[C@H](OCc1ccccc1)[C@@H](O)CCc1cccc2ccccc12>>C[C@H](OCc1ccccc1)[C@H](CCc1cccc2ccccc12)OS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US20140213591A1,C[Si](C)(C)CCOCCl.N#Cc1cccc2cc[nH]c12>>C[Si](C)(C)CCOCn1ccc2cccc(C#N)c21,,CN(C)C=O,,[H-].[Na+],,test
US20150344468A1,COC(=O)c1ccc(-n2ccc(C(C)c3ccc4c(c3)sc(=O)n4COCC[Si](C)(C)C)n2)nc1>>CC(c1ccc2c(c1)sc(=O)n2COCC[Si](C)(C)C)c1ccn(-c2ccc(CO)cn2)n1,,C1CCOC1,,[BH4-].[Li+],,test
US20080269196A1,N#Cc1ccc(F)cc1.SC1CCCCC1>>N#Cc1ccc(SC2CCCCC2)cc1,,CCO,,Cl,[Na],test
US04113940,Cc1nnc(OCC(=O)NC2C(=O)N3C(C(=O)OCC(Cl)(Cl)Cl)=CC(C)S[C@H]23)s1>>Cc1nnc(OCC(=O)NC2C(=O)N3C(C(=O)O)=CC(C)S[C@H]23)s1,[Zn],CN(C)C=O,,CC(=O)O,,test
US20150018363A1,Cn1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cc21.OCc1cc(F)cc(F)c1>>Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4cc(F)cc(F)c4)cc3=O)cc21,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20020127605A1,O=[N+]([O-])c1cccc(C2OCCO2)c1>>Nc1cccc(C2OCCO2)c1,[Pd],CCO,,,,test
US20160002259A1,Cc1c([C@@H]2CN3CCNC[C@H]3CO2)ccc2c1COC2=O.Cc1c([C@H]2CO2)ccc2c1COC2=O>>Cc1c([C@H](O)CN2CCN3C[C@@H](c4ccc5c(c4C)COC5=O)OC[C@@H]3C2)ccc2c1COC2=O,,CCO,,,,test
US20030176482A1,CC(O)(Cn1ccnc1)c1cc(Cl)ccc1O.CCCCCCCCCBr>>CCCCCCCCCOc1ccc(Cl)cc1C(C)(O)Cn1ccnc1,,CN(C)C=O,,[Na+].[OH-],,test
US04642308,Nc1ccc2ccc(Cl)nc2n1.Oc1ccccc1F>>Nc1ccc2ccc(Oc3ccccc3F)nc2n1,,CCO,,[K+].[OH-],,test
US20050065162A1,CC(Br)Br.COc1cc(NCC2CSCC(c3ccc(OC)c(OC)c3)N2)ccc1Cl>>COc1cc(N2CCN3C(CSCC3c3ccc(OC)c(OC)c3)C2)ccc1Cl,,CC(=O)N(C)C,,CCN(CC)CC,,test
US20120114739A1,C1COCCN1.C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)c1cc(C=O)nc2c(-c3cnc4ccccc4c3)cnn12>>C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)c1cc(CN2CCOCC2)nc2c(-c3cnc4ccccc4c3)cnn12,,CCO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20160107997A1,BrCC1CC1.Nc1cccc2cnccc12>>Nc1cccc2c[n+](CC3CC3)ccc12.[Br-],,CC#N,,,,test
US20070179122A1,CCOC(=O)C(F)(F)CNC(=O)c1ccc(Cl)s1>>O=C(NCC(F)(F)C(=O)O)c1ccc(Cl)s1,,C1CCOC1,O,[Li+].[OH-],,test
US20160145268A1,Cc1c(Br)ccc(O)c1N.O=C(n1ccnc1)n1ccnc1>>Cc1c(Br)ccc2oc(=O)[nH]c12,,C1CCOC1,O,CCOC(C)=O,,test
US20130018052A1,BrCc1ccccc1.NC(N)=S>>Br.N=C(N)SCc1ccccc1,,CC(C)O,,,,test
US20150307451A1,BrBr.CCc1ccc(C(=O)OC)c(O)c1>>CCc1cc(O)c(C(=O)OC)cc1Br,,CC(=O)O,,O,,test
US04929613,CC(=O)OC(C)=O.NC1CCC(c2cc(F)c(C(=O)O)cc2F)C1>>CC(=O)NC1CCC(c2cc(F)c(C(=O)O)cc2F)C1,,CC(=O)O,,,,test
US06673804B1,CI.O=S(=O)(NC(CO)CO)c1ccc(Oc2ccccc2)cc1>>CN(C(CO)CO)S(=O)(=O)c1ccc(Oc2ccccc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05696148,CCOC(=O)CC#N.O=CC1(Cl)Cc2ccccc2N1Cc1ccc(Cl)cc1>>CCOC(=O)C(C#N)=Cc1c(Cl)n(Cc2ccc(Cl)cc2)c2ccccc12,,CCO,,O,O=C([O-])[O-].[K+].[K+],test
US20100210633A1,COC(=O)C1(CC2CC2)CCN(C(=O)OC(C)(C)C)C1>>CC(C)(C)OC(=O)N1CCC(CC2CC2)(C(=O)O)C1,,CO,O,[K+].[OH-],,test
US20130345218A1,COC(=O)C1C2CCC(CC2)C1Nc1cc(-c2c[nH]c3ncc(F)cc23)c(C#N)cc1F>>N#Cc1cc(F)c(NC2C3CCC(CC3)C2C(=O)O)cc1-c1c[nH]c2ncc(F)cc12,,C1CCOC1,,[Na+].[OH-],,test
US20110281884A1,CCOC(C)=O.O=C(O)c1cc(Cl)cnc1Cl>>COC(=O)c1cc(Cl)cnc1Cl,,CCOC(C)=O,ClCCl,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US05106871,COC(=O)CBr.COCOc1ccc(CCC(=O)c2c(OC)cc(OC)c(CCC(C)C)c2O)cc1OC>>COCOc1ccc(CCC(=O)c2c(OC)cc(OC)c(CCC(C)C)c2OCC(=O)OC)cc1OC,,CN(C)C=O,,[H-].[Na+],,test
US20080004325A1,BrBr.COC(=O)c1scc(C)c1NC(=O)C(F)(F)F>>COC(=O)c1sc(Br)c(C)c1NC(=O)C(F)(F)F,,CC(=O)O,,,,test
US05064833,COc1ccc2nc(Cl)nc(N(C)c3ccccc3)c2c1.Cc1ccccc1N.Cl>>COc1ccc2nc(Nc3ccccc3C)nc(N(C)c3ccccc3)c2c1.Cl,,CCO,,,,test
US20080021032A1,CCS(=O)(=O)Cl.O=[N+]([O-])c1cc[nH]n1>>CCS(=O)(=O)n1ccc([N+](=O)[O-])n1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20060240048A1,CC(C)(C)c1cc(Cl)ncc1C(=O)NCC1CCCCC1.Nc1cccc(Cl)c1>>CC(C)(C)c1cc(Nc2cccc(Cl)c2)ncc1C(=O)NCC1CCCCC1,,C1COCCO1,,CS(=O)(=O)O,,test
US20140187545A1,CO.O=C1c2ccccc2C(=O)N1c1[nH]nc(O)c1Cc1cccc(Cl)c1Cl>>COc1n[nH]c(N2C(=O)c3ccccc3C2=O)c1Cc1cccc(Cl)c1Cl,,C1CCOC1,ClCCl,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140350019A1,CCOC(=O)COc1cccc(NCc2cc(-c3cccc(F)c3)ccc2F)c1>>O=C(O)COc1cccc(NCc2cc(-c3cccc(F)c3)ccc2F)c1,,C1CCOC1,O,Cl,[Li]O,test
US20090012308A1,O=S([O-])c1cccc2ccccc12.O=[N+]([O-])c1ccc(F)cc1CBr>>O=[N+]([O-])c1ccc(F)cc1CS(=O)(=O)c1cccc2ccccc12,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20050065135A1,CC(C)(C)[Si](C)(C)Cl.COc1ccc2c(c1)CC[C@]1(C=O)C2=C(CCCCCOCc2ccccc2)C[C@@]2(C)[C@H]1CC[C@@H]2O>>COc1ccc2c(c1)CC[C@]1(C=O)C2=C(CCCCCOCc2ccccc2)C[C@@]2(C)[C@H]1CC[C@@H]2O[Si](C)(C)C(C)(C)C,,CN(C)C=O,,O,c1c[nH]cn1,test
US07115624B1,CC(C)(C)OC(=O)c1c(OCc2ccccc2)sc2c1C(N=C=O)C(CN1C(=O)c3ccccc3C1=O)N(C(=O)OC(C)(C)C)C2.Cl>>CC(C)(C)OC(=O)c1c(OCc2ccccc2)sc2c1C(N=C=O)C(CN1C(=O)c3ccccc3C1=O)NC2.Cl,,CCOC(C)=O,,,,test
US20120245176A1,CC(C)(C)OC(=O)N1CCN(c2cnc([N+](=O)[O-])c(N)c2)CC1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N1CCN(c2cc(N)c([N+](=O)[O-])nc2Br)CC1,,CC(Cl)Cl,,,,test
US05399578,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].CCOC(=O)N(Cc1ccc(-c2ccccc2C#N)cc1)[C@H](C(=O)OCc1ccccc1)C(C)C>>CCOC(=O)N(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)[C@H](C(=O)OCc1ccccc1)C(C)C,,Cc1ccccc1C,,,,test
US04302469,c1ccc2c(c1)OCC(Cc1ncc[nH]1)O2>>c1ccc2c(c1)OCC(Cc1ncc[nH]1)O2,,CCOCC,,Cl,O=C([O-])[O-].[K+].[K+],test
US20130064770A1,CC(C)(C)OC(=O)N1CCN(CCCSc2nc3ccccc3s2)CC1>>c1ccc2sc(SCCCN3CCNCC3)nc2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04707486,C/C(N)=C/C(=O)OCCCN1CCC(c2ccccc2)(c2ccccc2)CC1.CC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(=O)OCCC#N>>CC1=C(C(=O)O)C(c2cccc([N+](=O)[O-])c2)C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(C)N1,,CC(C)O,,CC(=O)O,,test
US20110053916A1,N#CCc1ccc(-c2ncc([N+](=O)[O-])c(Cl)n2)cc1.Nc1cc(C2CC2)[nH]n1>>N#CCc1ccc(-c2ncc([N+](=O)[O-])c(Nc3cc(C4CC4)[nH]n3)n2)cc1,,CCO,,,,test
US20040019072A1,CCCCCCCOc1c(C(C)=CC#N)cc(C(C)(C)C)cc1C(C)(C)C>>CCCCCCCOc1c(C(C)CC#N)cc(C(C)(C)C)cc1C(C)(C)C,[Pd],CCOC(C)=O,,,,test
US20050080025A1,Cn1cc(C(=O)O)c(=O)c2ccc(Cl)cc21.NCCN>>Cn1cc(C(=O)O)c(=O)c2ccc(NCCN)cc21,,CN1CCCC1=O,CO,ClCCl,,test
US20150087646A1,CC(C)(C)OC(=O)NNc1cc(CNC(=O)C(C)(C)C)ccc1Cl.O=C=NC(=O)c1ccc(Cl)c(C(F)(F)F)c1>>CC(C)(C)C(=O)NCc1ccc(Cl)c(-n2nc(-c3ccc(Cl)c(C(F)(F)F)c3)[nH]c2=O)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04190561,CC1=CCC(C(C)O)C(C)(C)C1.O=CO>>CC1=CCC(C(C)OC=O)C(C)(C)C1,,O,,,,test
US20110269751A1,CCNCc1ccc(Cl)nc1.CSC(=C[N+](=O)[O-])SC>>CCN(Cc1ccc(Cl)nc1)C(=C[N+](=O)[O-])SC,,CCO,,,,test
US20080261941A1,CCOP(OCC)OCC.ClCc1cccc(Oc2ccc(Br)cn2)c1>>CCOP(=O)(Cc1cccc(Oc2ccc(Br)cn2)c1)OCC,,CCCCCCC,,,,test
US20120245153A1,Nc1ccc(N2C(=O)C3CCCCN3C2=O)c(Cl)c1.O=C(O)c1cccc(F)n1>>O=C(Nc1ccc(N2C(=O)C3CCCCN3C2=O)c(Cl)c1)c1cccc(F)n1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100004238A1,NC(=O)c1cc2c(Oc3ccc([N+](=O)[O-])cc3Cl)cccc2o1>>N#Cc1cc2c(Oc3ccc(N)cc3Cl)cccc2o1,,O=P(Cl)(Cl)Cl,,O,O=C([O-])O.[Na+],test
US20140243336A1,CN(C)C(=O)C(CNC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C>>CN(C)C(=O)[C@H](CN)NC(=O)OC(C)(C)C,[Pd],CO,,,,test
US04927958,C=CC(=O)Cc1ccc(F)cc1.O=CC(=O)O>>O=C(O)/C=C/C(=O)/C=C/c1ccc(F)cc1,,CC(=O)O,O,,,test
US04046900,COc1cc2[nH]c(C)c(C(=O)C(=O)Cl)c2cc1OC.O=C(c1ccccc1)C1CCNCC1>>COc1cc2[nH]c(C)c(C(=O)C(=O)N3CCC(C(=O)c4ccccc4)CC3)c2cc1OC,,ClC(Cl)Cl,O,CCOCC,O=C([O-])[O-].[K+].[K+],test
US20090118266A1,NNC(=O)c1ccc2c(c1)OCO2.S=C=S>>Sc1nnc(-c2ccc3c(c2)OCO3)o1,,O,,CO,[K+].[OH-],test
US20150336986A1,CC(C)(C)[Si](C)(C)Cl.Cn1c(=O)c2c(-c3cccc(F)c3)[nH]c(C(CC(O)CO)c3nc(Cl)cs3)c2n(C)c1=O>>Cn1c(=O)c2c(-c3cccc(F)c3)[nH]c(C(CC(O)CO[Si](C)(C)C(C)(C)C)c3nc(Cl)cs3)c2n(C)c1=O,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US20060089371A1,Brc1ccc(OCc2ccccc2)nc1.CCCC[Sn](Cl)(CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)c1ccc(OCc2ccccc2)nc1,,CCOCC,,[Li]CCCC,,test
US20100298336A1,CCc1cncc(CC)c1CBr.Cc1cc(O)nc(S)n1>>CCc1cncc(CC)c1CSc1nc(C)cc(O)n1,,CCO,,CCN(CC)CC,CCOCC,test
US04435403,CCOC(=O)c1ncc2[nH]c3ccc(N)cc3c2c1C.Cl/C=C\CCCl>>CCOC(=O)c1ncc2[nH]c3ccc(-n4cccc4)cc3c2c1C,,CCO,,CCN(C(C)C)C(C)C,,test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(CN4CCN(C(=O)OC(C)(C)C)CC4)cnc3Nc3cnc(OC)nc3)n2)cc1.CS(=O)(=O)Cl>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(CN4CCN(S(C)(=O)=O)CC4)cnc3Nc3cnc(OC)nc3)n2)cc1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20140275172A1,CCOC(=O)C(C)Br.Sc1cc(Cl)cc(Br)c1>>CCOC(=O)C(C)Sc1cc(Cl)cc(Br)c1,,O,,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20130131016A1,C=C(Br)C(F)(F)C(F)(F)F.OB(O)c1cc(Cl)cc(Cl)c1>>C=C(c1cc(Cl)cc(Cl)c1)C(F)(F)C(F)(F)F,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,O,O=C([O-])[O-].[K+].[K+],,test
US20020072597A1,CS(=O)(=O)c1nc(NCC(c2ccccc2)c2ccccc2)c2ncn(C3CCCCO3)c2n1.[C-]#N>>N#Cc1nc(NCC(c2ccccc2)c2ccccc2)c2ncn(C3CCCCO3)c2n1,,CN(C)C=O,,O,,test
US20090181965A1,C1CCNC1.O=C(Cl)C1CCCCC12OCCO2>>O=C(C1CCCCC12OCCO2)N1CCCC1,,CCOC(C)=O,,Cc1ccccc1,,test
US20090181959A1,COP(=O)(OC)C(=[N+]=[N-])C(C)=O.C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C(CC=O)C4CCCC4)c3)ncnc21>>C#CCC(C1CCCC1)n1cc(-c2ncnc3c2ccn3COCC[Si](C)(C)C)cn1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(C2CCN(c3ccc(O)cc3)CC2)c2ncnn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(C2CCN(c3ccc(O)cc3)CC2)c2ncnn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US04806145,CC(C)Oc1cc(-n2nc(C(F)F)[nH]c2=O)c(Cl)cc1Cl.CI>>CC(C)Oc1cc(-n2nc(C(F)F)n(C)c2=O)c(Cl)cc1Cl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080207900A1,C[C@@H](O)[C@@H]1CCC(c2cc(F)c(F)c(F)c2)N1C(=O)OC(C)(C)C>>C[C@@H](O)[C@@H]1CCC(c2cc(F)c(F)c(F)c2)N1,,CCOC(C)=O,,Cl,,test
US20090325981A1,CC(C)[Si](Cl)(C(C)C)C(C)C.COc1ccccc1O>>COc1ccccc1O[Si](C(C)C)(C(C)C)C(C)C,,CCOC(C)=O,,c1c[nH]cn1,,test
US20100029687A1,C[C@H](c1cccc2ccccc12)N(CC1CCN(c2cccc(C(=O)O)n2)CC1c1ccccc1)C(=O)OC(C)(C)C.Cl>>C[C@@H](NCC1CCN(c2cccc(C(=O)O)n2)CC1c1ccccc1)c1cccc2ccccc12.Cl,,CCOC(C)=O,,CC(C)OC(C)C,,test
US20050096337A1,CCCC(Oc1ccc(OCC(=O)OC(C)(C)C)c(C)c1)c1cnc(-c2ccc(C(F)(F)F)cc2)nc1C1CC1>>CCCC(Oc1ccc(OCC(=O)O)c(C)c1)c1cnc(-c2ccc(C(F)(F)F)cc2)nc1C1CC1,,C1CCOC1,,[Li+].[OH-],,test
US20030232848A1,COc1nn(Cc2ccccc2)c(N)c1-c1ccc2c(c1)OCO2.O=S(=O)(Cl)/C=C/c1ccccc1>>COc1nn(Cc2ccccc2)c(NS(=O)(=O)/C=C/c2ccccc2)c1-c1ccc2c(c1)OCO2,,c1ccncc1,,CN(C)c1ccccn1,,test
US20130203776A1,CS(=O)(=O)Cl.Fc1ccc2c(c1)[C@H]1CCCN1c1ccn3ncc(c3n1)CNCCO2>>CS(=O)(=O)N1CCOc2ccc(F)cc2[C@H]2CCCN2c2ccn3ncc(c3n2)C1,,CO,,CCN(C(C)C)C(C)C,ClCCl,test
US20060160788A1,CNS(=O)(=O)c1ccc(O)c(C(=O)OC)c1.OC1CCCC1>>CNS(=O)(=O)c1ccc(OC2CCCC2)c(C(=O)OC)c1,,C1CCOC1,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140221361A1,C=C(CBr)[C@@H]1CC[C@]2(C(=O)O[Si](C)(C)C(C)(C)C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC(C)(C)C)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.CN(C)CCN>>C=C(CNCCN(C)C)[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC(C)(C)C)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,ClCCCl,,,,test
US20080242665A1,CC(C)S(=O)(=O)Cl.Clc1nc(N2CCOCC2)c2sc(CN3CCNCC3)cc2n1>>CC(C)S(=O)(=O)N1CCN(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)CC1,,ClCCl,,CCN(CC)CC,,test
US20120208817A1,NC(N)=O.O=C(Cc1ccccc1)c1ccccc1.O=Cc1cc(F)c(O)c([N+](=O)[O-])c1>>O=C1NC(c2ccccc2)=C(c2ccccc2)C(c2cc(F)c(O)c([N+](=O)[O-])c2)N1,,CCO,,Cl,,test
US20080096921A1,CCOC(=O)c1ccc2cc(-c3ccc(SCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3)ccc2n1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1CSc1ccc(-c2ccc3nc(C(=O)O)ccc3c2)cc1,,C1CCOC1,,CCO,[Na+].[OH-],test
US20070123535A1,CCOC(=O)C(C(=O)OCC)C(c1ccccc1)c1c[nH]c2nccc(OC)c12>>COc1ccnc2[nH]cc(C(c3ccccc3)C(C(=O)O)C(=O)O)c12,,C1CCOC1,CCO,O,[K+].[OH-],test
US20100240702A1,C=C(C)n1c(=O)n(Cc2c(C(=O)OC)ccc3c(C)c(C)n(C)c23)c2ccccc21>>COC(=O)c1ccc2c(C)c(C)n(C)c2c1Cn1c(=O)[nH]c2ccccc21,,CO,,Cl,,test
US20050171087A1,O=C(N[C@@H]1CCCN2c3cc(NCc4ccccc4)ccc3Oc3ccccc3[C@H]12)C(F)(F)F>>Nc1ccc2c(c1)N1CCC[C@@H](NC(=O)C(F)(F)F)[C@H]1c1ccccc1O2,[Pd],CCO,,C1COCCO1,Cl,test
US20070010537A1,COC(=O)c1cc([N+](=O)[O-])c(Cl)s1>>COC(=O)c1cc(N)c(Cl)s1,,CCO,Cl,O=C([O-])O.[Na+],,test
US20120252801A1,CC=O.NC[C@@H](O)c1ccccc1>>CCNC[C@@H](O)c1ccccc1,,CCO,,[BH4-].[Na+],,test
US20150210688A1,Cc1nn(Cc2ccccc2)cc1C(O)C(F)(F)F.S=C(Cl)Oc1ccccc1>>FC(F)(F)C(OC(=S)Oc1ccccc1)c1cnn(Cc2ccccc2)c1,CN(C)c1ccncc1,Cc1ccccc1,,,,test
US20080194618A1,COc1cccc(CBr)c1.OC(c1ccccc1)(c1ccccc1)C12CCN(CC1)C2>>COc1cccc(C[N+]23CCC(C(O)(c4ccccc4)c4ccccc4)(CC2)C3)c1.[Br-],,CC#N,,,,test
US20090111859A1,CC#C[C@@H](CC(=O)OC)c1ccc(OCc2ccc(C(C)(C)C)c(-c3cc(OC)ccc3F)c2)cc1>>CC#C[C@@H](CC(=O)O)c1ccc(OCc2ccc(C(C)(C)C)c(-c3cc(OC)ccc3F)c2)cc1,,C1CCOC1,CCO,[Li+].[OH-],,test
US20060211734A1,BrCC1CC1.OC1CCNCC1>>OC1CCN(CC2CC2)CC1,,C1CCOC1,CCOC(C)=O,,,test
US20050222118A1,CCc1nnc(NC(=O)Oc2ccccc2)s1.NCCCN1CC(Cc2ccc(Cl)cc2)C1>>CCc1nnc(NC(=O)NCCCN2CC(Cc3ccc(Cl)cc3)C2)s1,,CS(C)=O,,,,test
US20090233918A1,C1CCOC1.CCN(CC)CC.Cn1c(Cl)nc(-c2ccncn2)cc1=O>>Cn1c(N2CCO[C@@H]3CCCC[C@H]32)nc(-c2ccncn2)cc1=O,,C1CCOC1,,,,test
US20080312226A1,O=C(Nc1ccnnc1)OCC(Cl)(Cl)Cl.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>O=C(Nc1ccnnc1)N1CCN(c2nc(-c3ccccc3)ns2)CC1,,O,,CCN(C(C)C)C(C)C,CS(C)=O,test
US20040167160A1,CCOc1c(C(=O)c2cc(Br)ccc2F)cc(C(C)C)cc1C(C)C.NN=C(c1ccccc1)c1ccccc1>>CCOc1c(-c2n[nH]c3ccc(Br)cc23)cc(C(C)C)cc1C(C)C,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20050245561A1,CC#N.CCOC(=O)Cn1cc(C(=O)O)c2nc3c(C)cccc3cc2c1=O.O=C(n1ccnc1)n1ccnc1>>CCOC(=O)Cn1cc(C(=O)NCCN(C)C)c2nc3c(C)cccc3cc2c1=O,,CC#N,,,,test
US20150353456A1,O.Oc1ccc2ccc(O)c(-c3c(O)ccc4ccc(O)cc34)c2c1>>O.Oc1ccc2ccc(O)c(-c3c(O)ccc4ccc(O)cc34)c2c1,,O,,,,test
US20040009995A1,CCOC(=O)CCBr.CSc1sc(C(=N)NC(=O)OC(C)(C)C)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2CO)c1>>CCOC(=O)CCOCc1cccc(C)c1-c1cccc(S(=O)(=O)c2cc(C(=N)NC(=O)OC(C)(C)C)sc2SC)c1,,CN(C)C=O,,[H-].[Na+],,test
US20120010189A1,CC(C)(C)OC(=O)N1CC(OS(C)(=O)=O)C1.Cc1cc(O)ccc1C=O>>Cc1cc(OC2CN(C(=O)OC(C)(C)C)C2)ccc1C=O,,CN(C)C=O,,O,[H-].[Na+],test
US20160102071A1,BrP(Br)Br.OCc1ccc2scc(Br)c2c1>>BrCc1ccc2scc(Br)c2c1,,CN(C)C=O,ClCCl,O,,test
US20040127527A1,BrBr.CCc1c[nH]c(-c2ccc(F)cc2)n1>>CCc1nc(-c2ccc(F)cc2)[nH]c1Br,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US04927958,COc1ccc(/C=C/C(C)=O)c(OC)c1OC.O=CC(=O)O>>COc1ccc(/C=C/C(=O)/C=C/C(=O)O)c(OC)c1OC,,CC(=O)O,O,,,test
US05055579,CC[n+]1c(C)sc2ccccc21.O=C(Cl)c1cccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)c1>>CCN1C(=CC(=O)c2cccc(-c3nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n3)c2)Sc2ccccc21,,CCN(CC)CC,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US06034086,CCN=C=NCCCN(C)C.O=C(O)c1c(C2CC2)[nH]c2c(C(F)(F)F)c(N3CCN(c4ccccn4)CC3)c(F)cc2c1=O.OCCN1CCOCC1>>N.O=C(OCCN1CCOCC1)c1cn(C2CC2)c2c(C(F)(F)F)c(N3CCN(c4ccccn4)CC3)c(F)cc2c1=O,CN(C)c1ccncc1,ClCCl,,Cl,,test
US20110218182A1,CC(=O)O[BH-](OC(C)=O)OC(C)=O.CCC=O.ClCCl.N[C@@H]1CCCN(c2c(Cl)cccc2/C=C2\SC(=O)NC2=O)C1>>CCCN(CCC)[C@@H]1CCCN(c2c(Cl)cccc2/C=C2\SC(=O)NC2=O)C1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20100137281A1,CCc1cc2c(=O)n(CC(=O)OC)c(=O)[nH]c2s1.N#Cc1ccccc1-c1ccc(CBr)cc1>>CCc1cc2c(=O)n(CC(=O)OC)c(=O)n(Cc3ccc(-c4ccccc4C#N)cc3)c2s1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04252738,COC1(C)OC2CCC2O1.C[Si](C)(C)Cl>>CC(=O)O[C@@H]1CC[C@H]1Cl,,ClCCl,,,,test
US20070275961A1,CCNCC.NS(=O)(=O)c1ccc(Nc2cc(Cl)nc3ncnn23)cc1>>CCN(CC)c1cc(Nc2ccc(S(N)(=O)=O)cc2)n2ncnc2n1,,CCO,,,,test
US04430346,CC(C)C(=O)OC(=O)C(C)C.Cl.N=C(N)NCCCC[C@H](O)CC(N)=O>>CC(C)C(=O)O[C@@H](CCCCNC(=N)N)CC(N)=O.Cl,,c1ccncc1,,CN(C)C=O,,test
US03981717,CCO.CCOC(OCC)OCC.COc1ccc(N)cc1.N#CCC#N>>COc1ccc(NC(C)=C(C#N)C#N)cc1,,CCO,,,,test
US20050137171A1,CC(C)(C)OC(=O)N1CCN(CCOc2ccc3c(c2)cc(-c2nn(C(=O)OC(C)(C)C)c4ccc(O[PH](=O)CO)cc24)n3C(=O)OC(C)(C)C)CC1>>CP(=O)(O)Oc1ccc2[nH]nc(-c3cc4cc(OCCN5CCNCC5)ccc4[nH]3)c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05770615,CC(C)(C)[Si](C)(C)Cl.CS(=O)(=O)Nc1cc([C@@H](O)CI)ccc1OCc1ccccc1>>CC(C)(C)[Si](C)(C)O[C@@H](CI)c1ccc(OCc2ccccc2)c(NS(C)(=O)=O)c1,CN(C)c1ccncc1,CCCCCCC,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,test
US20100331293A1,Nc1cncc(C2=CCOCC2)c1>>Nc1cncc(C2CCOCC2)c1,[Pd],CCO,CCOC(C)=O,,,test
US20160024086A1,O=S(=O)(Cc1ccccc1)N1CCC(Cn2ccc3nc(-c4cnn(C5CCCCO5)c4)ccc32)CC1>>O=S(=O)(Cc1ccccc1)N1CCC(Cn2ccc3nc(-c4cn[nH]c4)ccc32)CC1,,CO,ClCCl,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20040209776A1,CC(C(=O)O)c1ccc(O)c([N+](=O)[O-])c1.CCc1nsc(N)c1Cl>>CCc1nsc(NC(=O)C(C)c2ccc(O)c([N+](=O)[O-])c2)c1Cl,,ClCCCl,ClCCl,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20020143035A1,CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCN1.O=C=Nc1cc(Cl)cc(Cl)c1>>CC(C)(C)OC(=O)N1CCN2C(=O)N(c3cc(Cl)cc(Cl)c3)C(=O)C2C1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20130165666A1,CC(C)(C)OC(=O)NNCc1cc(Br)ccc1O.COC(=O)/C(=C\N(C)C)C(C)=O>>COC(=O)c1cnn(Cc2cc(Br)ccc2O)c1C,,ClCCl,O=C(O)C(F)(F)F,CCO,,test
US20090111809A1,COC(=O)c1ccc(-c2ccc(C[C@@H]3CCN(N4CCC(O[Si](C(C)C)(C(C)C)C(C)C)CC4)C3=O)c(Cl)c2)cc1>>CC(C)[Si](OC1CCN(N2CC[C@@H](Cc3ccc(-c4ccc(C(=O)O)cc4)cc3Cl)C2=O)CC1)(C(C)C)C(C)C,,C1CCOC1,,[Li+].[OH-],,test
US20100184813A1,CC(C)(C)OC(=O)Nc1ccc(Br)cc1F.CCOC(=O)C1CC=C(B2OC(C)(C)C(C)(C)O2)CC1>>CCOC(=O)C1CC=C(c2ccc(NC(=O)OC(C)(C)C)c(F)c2)CC1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US08952004B2,CC(C)(C)N.O=C(O)CC1CCN(c2nc(C(F)(F)F)ccc2NC(=O)c2cccc(Cl)c2)CC1>>CC(C)(C)NC(=O)CC1CCN(c2nc(C(F)(F)F)ccc2NC(=O)c2cccc(Cl)c2)CC1,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20140275172A1,COC(=O)c1cc(OC(F)(F)F)ccc1O.O=C1CCC(=O)N1Br>>COC(=O)c1cc(OC(F)(F)F)cc(Br)c1O,,CC#N,,,,test
US20160214971A1,COC(=O)c1cc(OC)c(Br)cc1F>>COc1cc(C(=O)O)c(F)cc1Br,,C1CCOC1,O,[Li]O,,test
US20090233919A1,C1CCNC1.COc1cc(-n2ccc3nc(-c4ccc(Cl)cc4)sc3c2=O)ccc1CCC=O>>COc1cc(-n2ccc3nc(-c4ccc(Cl)cc4)sc3c2=O)ccc1CCCN1CCCC1,,ClCCCl,,CC(=O)O,[Na+].[OH-],test
US20130029962A1,COc1cc(N)cnc1N1CCCC1.O=C(Cl)Oc1ccccc1>>COc1cc(NC(=O)Oc2ccccc2)cnc1N1CCCC1,,CC#N,O,c1ccncc1,,test
US20090005344A1,COc1ccc(-c2nc3ccccc3[nH]2)cc1.OB(O)CCCCCBr>>COc1ccc(-c2nc3ccccc3n2CCCCCB(O)O)cc1,,C1CCOC1,,[H-].[Na+],,test
US20110028450A1,CCS(=O)c1cc2c(cc1OC)CCn1c-2cc2c1C(=O)N(C(C)(C)C)CCCC2.O=C1CCC(=O)N1Br>>CCS(=O)c1cc2c(cc1OC)CCn1c3c(c(Br)c1-2)CCCCN(C(C)(C)C)C3=O,,CN(C)C=O,O,,,test
US03995045,NCCCN1CCC(c2ccccc2)CC1.O=c1oc(=O)c2ccccc2c2ccccc12>>O=C(O)c1ccccc1-c1ccccc1C(=O)NCCCN1CCC(c2ccccc2)CC1,,Cc1ccccc1,,Cl,,test
US20040014766A1,CCCCn1c(=O)[nH]c(=O)c2c1nc(Cc1ccc(NC(C)=O)cc1)n2COC(=O)C(C)(C)C.COc1ccc(F)c(CBr)c1>>CCCCn1c(=O)n(Cc2cc(OC)ccc2F)c(=O)c2c1nc(Cc1ccc(NC(C)=O)cc1)n2COC(=O)C(C)(C)C,,CC#N,CCOC(C)=O,C1CCC2=NCCCN2CC1,,test
US20150368228A1,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.Nc1nc(Nc2cc(Cl)c(Br)c(Cl)c2)n[nH]1>>Nc1ccc(-c2c(Cl)cc(Nc3n[nH]c(N)n3)cc2Cl)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US04568670,CCSC(=N)N(C)C.COP(=S)(Cl)OC>>CCSC(=NP(=S)(OC)OC)N(C)C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20020128290A1,C=CCBr.COc1ccc(C=O)c(Br)c1O>>C=CCOc1c(OC)ccc(C=O)c1Br,,CN(C)C=O,,O,[H-].[Na+],test
US20160122345A1,CCSc1ccc([C@H](CO)N[S@](=O)C(C)(C)C)cc1.CI>>CCSc1ccc([C@H](COC)N[S@](=O)C(C)(C)C)cc1,,C1CCOC1,,[H-].[Na+],,test
US20010046641A1,C=CC(=O)Cl.CCC1(O)C2CC3CC(C2)CC1C3>>C=CC(=O)OC1(CC)C2CC3CC(C2)CC1C3,,CC(=O)CC(C)C,,CCN(CC)CC,,test
US20120295884A1,COc1cc(F)c(F)c(CN=[N+]=[N-])c1>>COc1cc(F)c(F)c(CN)c1,[Pd],CCO,,,,test
US20030195232A1,COCOc1cnccc1CCCO.Oc1cccnc1Sc1cccc(Br)c1>>Oc1cnccc1CCCOc1cccnc1Sc1cccc(Br)c1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04692184,CCOC(=O)C1=C(C(F)(F)F)NC(C(F)(F)F)=C(C(=O)OCC)C1C1CC1>>CCOC(=O)c1c(C(F)F)nc(C(F)(F)F)c(C(=O)OCC)c1C1CC1,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20160229865A1,CC(C)I.O=[N+]([O-])c1cn[nH]c1>>CC(C)n1cc([N+](=O)[O-])cn1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090186900A1,CCOC(=O)Cn1ccc(-c2ccc(-c3ccc(OC)c(CC)c3)cc2)n1>>CCc1cc(-c2ccc(-c3ccn(CC(=O)O)n3)cc2)ccc1OC,,C1CCOC1,CCO,[Na+].[OH-],,test
US20030166634A1,C=CC[Mg]Br.CCC1(CC)CC(=O)CC(C)(C)C1>>C=CCC1(O)CC(C)(C)CC(CC)(CC)C1,,CCOCC,,[Cl-].[NH4+],,test
US20100216788A1,CC(C)(C)OC(=O)NCCn1ccc2ncnc(Cl)c21.Nc1ccc(Oc2cccc(Oc3ccccc3)c2)c(Cl)c1>>CC(C)(C)OC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(Oc5ccccc5)c4)c(Cl)c3)c21,,CC(C)O,,O=C([O-])O.[Na+],,test
US20140275179A1,CCc1ccc(-c2nsc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)OC(C)(C)C)cc2F)cc1>>CCc1ccc(-c2nsc(C(F)(F)F)c2COc2c(F)cc(CCC(=O)O)cc2F)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06599917B1,C#CC1(O)CCCC1.OC1(C#Cc2ncc(Br)cc2Cc2ccccc2)CN2CCC1CC2>>OC1(C#Cc2cnc(C#CC3(O)CN4CCC3CC4)c(Cc3ccccc3)c2)CCCC1,,CN(C)C=O,,CCN(CC)CC,O=C([O-])[O-].[Na+].[Na+],test
US20150313853A1,COc1ccccc1NC(=O)c1c(N)cccc1Sc1ccc([N+](=O)[O-])cc1.O=S(=O)(Cl)c1ccccc1>>COc1ccccc1NC(=O)c1c(NS(=O)(=O)c2ccccc2)cccc1Sc1ccc([N+](=O)[O-])cc1,,c1ccncc1,,,,test
US20160257651A1,BrCBr.Cc1cc(=O)[nH]c2c(O)c(Br)ccc12>>Cc1cc(=O)n2c3c(c(Br)ccc13)OC2,,O,,CC(=O)N(C)C,O=C([O-])[O-].[K+].[K+],test
US04572912,CC(=O)OC(C)=O.Cc1c(C)c2c(c(C)c1O)CCC(C)(COc1ccc(CC3SC(=O)NC3=O)cc1)O2>>CC(=O)Oc1c(C)c(C)c2c(c1C)CCC(C)(COc1ccc(CC3SC(=O)NC3=O)cc1)O2,,c1ccccc1,,c1ccncc1,,test
US20130053409A1,COc1cc(N2CC(N(C)C)C2)c([N+](=O)[O-])cc1Nc1nccc(-c2cnn3ccccc23)n1>>COc1cc(N2CC(N(C)C)C2)c(N)cc1Nc1nccc(-c2cnn3ccccc23)n1,[Fe],O,,CCO,[Cl-].[NH4+],test
US20060194741A1,CC(C)(C)OC(=O)NC(C(=O)N1CCCC1Cc1cn(CCOCCn2cc(CC3CCCN3C(=O)C(NC(=O)OC(C)(C)C)C3CCCCC3)c3ccccc32)c2ccccc12)C1CCCCC1>>NC(C(=O)N1CCCC1Cc1cn(CCOCCn2cc(CC3CCCN3C(=O)C(N)C3CCCCC3)c3ccccc32)c2ccccc12)C1CCCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05244910,CCCC[Zn]CCCC.O=Cc1ccco1>>CCCC[C@H](O)c1ccco1,,Cc1ccccc1,,[Cl-].[NH4+],,test
US04203987,ClCc1ccncc1.O=C1Nc2ccccc2N2CCNCC12>>O=C1Nc2ccccc2N2CCN(Cc3ccncc3)CC12,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US05914402,COc1cccc2c1=NC(=O)C1CCOC=21.Cc1ccccc1N.OCCOCCO>>COc1ccccc1N1CCc2c1c1cccc(OC)c1[nH]c2=O,,O,,,,test
US04022769,CCC(=O)O.CCC(=O)O.C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43CO)[C@@H]1CC[C@@H]2O>>CCC(=O)O.CCC(=O)O.C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)C=C[C@@]43CO)[C@@H]1CC[C@@H]2O,,C1COCCO1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20150141406A1,CC1(C)OB(c2ccc(N3CCOCC3=O)cc2)OC1(C)C.COc1nccc2c1c(OS(=O)(=O)C(F)(F)F)nn2-c1c(F)cccc1F>>COc1nccc2c1c(-c1ccc(N3CCOCC3=O)cc1)nn2-c1c(F)cccc1F,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20030139390A1,Nc1cc(Cl)c(Sc2ccc3ccccc3c2)c(Cl)c1.O=S(=O)(Cl)c1ccc(Cl)nc1>>O=S(=O)(Nc1cc(Cl)c(Sc2ccc3ccccc3c2)c(Cl)c1)c1ccc(Cl)nc1,,C1CCOC1,,c1ccncc1,,test
US04372953,Cn1nnnc1S.O=S(=O)(CCCCl)c1ccccn1>>Cn1nnnc1SCCCS(=O)(=O)c1ccccn1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05780482,CCOC(=O)c1cnc2nc(C)c(OCC)cc2c1Cl.NC(=O)COc1ccc(N)cc1>>CCOC(=O)c1cnc2nc(C)c(OCC)cc2c1Nc1ccc(OCC(N)=O)cc1.Cl,,CCO,,,,test
US20140200227A1,CC(C)(C)OC(=O)N[C@@H]1CNC[C@H](C(F)(F)F)C1.O=[N+]([O-])c1cnc2c(c1I)CCO2>>CC(C)(C)OC(=O)N[C@H]1C[C@@H](C(F)(F)F)CN(c2c([N+](=O)[O-])cnc3c2CCO3)C1,,CCO,,CCN(C(C)C)C(C)C,,test
US20150080549A1,CC(C)(C)OC(=O)N[C@@H](CSSC(C)(C)C)C(=O)NCc1ccccc1>>CC(C)(C)SSC[C@H](N)C(=O)NCc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120059028A1,CCCC(C(=O)OC)c1c(C)nc2scc(-c3ccccc3)c2c1-c1ccc(C)cc1>>CCCC(C(=O)O)c1c(C)nc2scc(-c3ccccc3)c2c1-c1ccc(C)cc1,,CO,,[Na+].[OH-],,test
US20020156311A1,CC(=O)OC(C)=O.Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccc(Oc2cccc(OCCCN)c2)cc1>>CC(=O)NCCCOc1cccc(Oc2ccc(CN(Cc3ccccc3)c3cccc(NS(C)(=O)=O)c3C)cc2)c1,,ClCCl,,,,test
US06689806B1,CC(C)c1ccccc1O.O=C1Cc2c(CCO)cccc2N1>>CC(C)c1ccccc1OCCc1cccc2c1CC(=O)N2,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080167360A1,CC1(C)CC(=C(c2ccccc2)c2ccc(O)cc2)CC(C)(C)C1.CCOC(=O)CCCCl>>CCOC(=O)CCCOc1ccc(C(=C2CC(C)(C)CC(C)(C)C2)c2ccccc2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090239915A1,N#Cc1ccc2[nH]c(-c3ccc(F)cc3)nc2c1.NO>>N=C(NO)c1ccc2[nH]c(-c3ccc(F)cc3)nc2c1,,CCO,,CCN(CC)CC,Cl,test
US20070276138A1,COC(=O)C(C)(Oc1ccc(Cl)cc1)c1ccc(OCc2ccccc2)cc1>>COC(=O)C(C)(Oc1ccccc1)c1ccc(O)cc1,[Pd],CCO,,,,test
US20120022056A1,C=CCc1cccc2c1OCC(NCC(OC)OC)=N2>>C=CCc1cccc2c1OCc1nccn1-2,,CO,,Cl,,test
US04595535,CSc1nc(Cc2ccccc2N)n[nH]1.O=C(n1ccnc1)n1ccnc1>>CSc1nc2n(n1)C(=O)Nc1ccccc1C2,,ClCCl,,,,test
US20020156081A1,CC(=O)O.CC(=O)O.CN1CCN([C@H]2CC[C@@H](n3nc(-c4ccc(NC(=O)CCc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1>>CC(=O)O.CC(=O)O.CN1CCN([C@@H]2CC[C@H](n3nc(-c4ccc(NCCCc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04874775,CCCCC(Nc1ccc(F)cc1)c1cccnc1.CS(=O)(=O)Cl>>CCCCC(c1cccnc1)N(c1ccc(F)cc1)S(C)(=O)=O,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20160024142A1,C[C@]12CC[C@@H]3c4ccc(C#N)cc4CC[C@H]3[C@@H]1CC=C2OS(=O)(=O)C(F)(F)F.OB(O)c1cncc(F)c1>>C[C@]12CC[C@@H]3c4ccc(C#N)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(F)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US05410061,COC(=O)c1ccc2ccn(C)c2c1.ClCc1ccc(OCc2ccc3ccccc3n2)cc1>>COC(=O)c1ccc2c(Cc3ccc(OCc4ccc5ccccc5n4)cc3)cn(C)c2c1,O=[Ag],C1COCCO1,,,,test
US04219648,BrBr.O=S1(=O)Cc2ccccc2C1>>O=S1(=O)Cc2cccc(Br)c2C1,[Fe],ClC(Cl)(Cl)Cl,,,,test
US20070099912A1,Cc1ccc(S(=O)(=O)OC[C@@H]2CCCN2C(=O)OC(C)(C)C)cc1.O=c1c2ccc3[nH]ccc3c2ccn1Cc1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCC[C@H]1Cn1ccc2c3ccn(Cc4ccc(F)cc4)c(=O)c3ccc21,,CN(C)C=O,,Cl,[H-].[Na+],test
US20090118275A1,CS(=O)(=O)N1CCN(Cc2nc3c(N4CCOCC4)nc(Cl)nc3s2)CC1.OB(O)c1cccc2[nH]ncc12>>CS(=O)(=O)N1CCN(Cc2nc3c(N4CCOCC4)nc(-c4cccc5[nH]ncc45)nc3s2)CC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20060211678A1,C1=C(c2cc3c(Nc4cccc5ccccc45)ncnc3[nH]2)CCNC1.CC(C)(C)N=C=O>>CC(C)(C)NC(=O)N1CC=C(c2cc3c(Nc4cccc5ccccc45)ncnc3[nH]2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20130281450A1,Cc1[nH]cc2c1C(=O)CCC2.O=C1CCC(=O)N1Br>>Cc1[nH]c(Br)c2c1C(=O)CCC2,,C1CCOC1,,O=S([O-])[O-].[Na+].[Na+],,test
US20130079341A1,CCOC(=O)CN.COC(=O)c1cc([N+](=O)[O-])c(Cl)s1>>CCOC(=O)CNc1sc(C(=O)OC)cc1[N+](=O)[O-],,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US06514961B1,CC(C)(C)c1ccc(OC2CN(C(c3ccccc3)c3ccccc3)C2)cc1.C[C@@H](O)CN.O=C(Cl)Cl>>C[C@@H](O)CNC(=O)N1CC(Oc2ccc(C(C)(C)C)cc2)C1,,ClCCl,,O,,test
US05026856,CC1COc2c(F)c(F)cc3c(=O)c(C(=O)O)cn1c23.CCNc1ccc2c(c1)CNC2>>CCNc1ccc2c(c1)CN(c1c(F)cc3c(=O)c(C(=O)O)cn4c3c1OCC4C)C2,,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20160137664A1,CCOC(=O)CC(C)=O.CCOc1ccc(C=C(C#N)C(N)=S)cc1>>CCOC(=O)c1c(C)[nH]c(=S)c(C#N)c1-c1ccc(OCC)cc1,,CCO,,C1CCNCC1,,test
US20070123504A1,O=C(O)CNC(=O)c1ccccc1Cl.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(NC(C(=O)O)C(O)(O)C(F)(F)F)c1ccccc1Cl,,CC(C)=O,,,,test
US04775671,CCCC(N)=NO.O=C1c2c(Cl)cccc2-n2cnc(C(=O)n3ccnc3)c2[C@@H]2CCCN12>>CCCc1noc(-c2ncn3c2[C@@H]2CCCN2C(=O)c2c(Cl)cccc2-3)n1,,CN(C)C=O,,CC(=O)O,,test
US06090825,C=O.O=C(CNC(=O)C1CCN(C(=O)OCc2ccccc2)CC1)c1ccc(Cl)cc1>>O=C(NC(CO)C(=O)c1ccc(Cl)cc1)C1CCN(C(=O)OCc2ccccc2)CC1,,CS(C)=O,O,O=C([O-])O.[Na+],,test
US20120041009A1,Cc1nc(C(N)=NO)cc(-c2ccccc2C)n1.O=C(n1ccnc1)n1ccnc1>>Cc1nc(-c2nc(=O)o[nH]2)cc(-c2ccccc2C)n1,,C1CCOC1,O,C1CCC2=NCCCN2CC1,Cl,test
US20150080362A1,CCc1c(OC)c(C(=O)O)c(=O)n(Cc2ccccc2)c1-c1ccc(N(C)C)cc1>>CCc1c(-c2ccc(N(C)C)cc2)[nH]c(=O)c(C(=O)O)c1OC,,CC(=O)O,CO,,,test
US20110207777A1,CO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C)cc(F)c3N)CC2)CC1.ClCCl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CO[C@@H]1CC[C@@H](N2CCC(n3c(=O)[nH]c4c(F)cc(C)cc43)CC2)CC1.Cl,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20130331378A1,COC(=O)c1cccc(C=O)n1.C[Si](C)(C)c1c(Cl)ccc2c(Br)c(N3CCCC3)nn12>>COC(=O)c1cccc(C(O)c2c(N3CCCC3)nn3c([Si](C)(C)C)c(Cl)ccc23)n1,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US20110183973A1,COc1c(C)cccc1C(=O)O.Nc1cc(-c2cccc3[nH]ccc23)cc2[nH]ncc12>>COc1c(C)cccc1C(=O)Nc1cc(-c2cccc3[nH]ccc23)cc2[nH]ncc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030100576A1,C[N-][C@@H]1CCC[C@H](n2c(=O)c3c(C)onc3c3c(Cl)cccc32)C1.O=C(Cl)c1cccnc1>>Cc1onc2c1c(=O)n([C@H]1CCC[C@@H](CNC(=O)c3cccnc3)C1)c1cccc(Cl)c21,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,Cl,test
US20150329497A1,COC(=O)c1cc(OC)c(OC)cc1N.COc1cc2nc(C3CC3)nc(N3CCN(c4ccccc4OC)CC3)c2cc1OC>>COc1cc2nc(C)nc(O)c2cc1OC,,CC#N,,C1COCCO1,Cl,test
US20110230458A1,CCCCc1nnc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1-c1ccc(OC2CCCCC2)c(C#N)c1.Cl.ClCCl>>CCCCc1nnc(OC2CCNCC2)cc1-c1ccc(OC2CCCCC2)c(C#N)c1.Cl.Cl,,C1COCCO1,Cl,,,test
US20080167269A1,C[Si](C)(C)CC[Si](C)(C)CCCOCC1CO1.NCCO>>C[Si](C)(C)CC[Si](C)(C)CCCOCC(O)CNCCO,,CCO,,,,test
US20080318945A1,CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCN(C(=O)OCc2ccccc2)CC1>>CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCNCC1,[Pd],CCO,,,,test
US06410556B1,CC(C)(C)OC(=O)c1c(OCc2ccccc2)sc2c1C(N=C=O)[C@H](CN1C(=O)c3ccccc3C1=O)N(C(=O)OC(C)(C)C)C2.Cl>>CC(C)(C)OC(=O)c1c(OCc2ccccc2)sc2c1C(N=C=O)[C@H](CN1C(=O)c3ccccc3C1=O)NC2.Cl,,CCOC(C)=O,,,,test
US20150011526A1,C1CCNC1.O=C(O)c1ccccc1C1CCN(CCc2ccccc2N2CCCCC2=O)C1>>O=C(c1ccccc1C1CCN(CCc2ccccc2N2CCCCC2=O)C1)N1CCCC1,,ClCCl,,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,,test
US05350757,COC(=O)C1Cc2c(ccc(OC)c2Oc2ccc([N+](=O)[O-])cc2)CN1C(=O)C(c1ccccc1)c1ccccc1>>COC(=O)C1Cc2c(ccc(OC)c2Oc2ccc(N)cc2)CN1C(=O)C(c1ccccc1)c1ccccc1,[Pd],C1CCOC1,CO,,,test
US20130237519A1,CC(C)(N)CO.Cc1ncc(C(=O)NCCN2CCCC2(C)C)cc1NC(=O)c1cnn2cc(-c3ccc(C(=O)O)c(F)c3)ccc12>>Cc1ncc(C(=O)NCCN2CCCC2(C)C)cc1NC(=O)c1cnn2cc(-c3ccc(C(=O)NC(C)(C)CO)c(F)c3)ccc12,,CN(C)C=O,ClCCl,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04865618,COc1c(Cl)cc([N+](=O)[O-])c(OC)c1[N+](=O)[O-]>>COc1c(N)cc(Cl)c(OC)c1[N+](=O)[O-],[Pd],CCO,,C1=CCCCC1,,test
US20090258904A1,O=[Cr](=O)=O.OCCCCCOCc1ccccc1>>O=C(O)CCCCOCc1ccccc1,,CC(C)=O,,O=S(=O)(O)O,,test
US20100048564A1,Cc1cc(Oc2ccc([N+](=O)[O-])c(CNC(=O)OC(C)(C)C)c2)ccc1F>>Cc1cc(Oc2ccc(N)c(CNC(=O)OC(C)(C)C)c2)ccc1F,[Fe],O,,CCO,[Cl-].[NH4+],test
US20020193614A1,CC(Nc1ccc([N+](=O)[O-])cc1C(=O)NCc1ccc2c(c1)OCO2)C(=O)OC(C)(C)C>>C[C@H](Nc1ccc([N+](=O)[O-])cc1C(=O)NCc1ccc2c(c1)OCO2)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080009530A1,CCCCCS(=O)(=O)NC(=O)/C=C/c1ccc(OCCC2(C)OCCO2)cc1Oc1ncc(C(F)(F)F)cc1Cl>>CCCCCS(=O)(=O)NC(=O)/C=C/c1ccc(OCCC(C)=O)cc1Oc1ncc(C(F)(F)F)cc1Cl,,C1CCOC1,,Cl,,test
US20130096113A1,Cl.Nc1cc(I)ccn1.c1cn[nH]c1>>Cl.Nc1cc(-n2cccn2)ccn1,,CCO,CCOCC,C1COCCO1,,test
US20050026922A1,C1CSCN1.ClCc1ccc(Cl)nc1>>Clc1ccc(CN2CCSC2)cn1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070287697A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)CNC1=S.CCC(O)CN>>CCC(O)CN=C1NC[C@H](c2cccc(F)c2F)CC[C@H]1NC(=O)OC(C)(C)C,Cl[Hg]Cl,CCO,,,,test
US20090264440A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COCCNCc1ccc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)nc1>>COCCN(Cc1ccc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)nc1)C(=O)OC(C)(C)C,,C1CCOC1,,,,test
US20150031685A1,Cc1noc(-c2cccc([C@@H](CN3CC[C@H](O[Si](C)(C)C(C)(C)C)C3)N(C)C(=O)OCc3ccccc3)c2)n1>>CN[C@H](CN1CC[C@H](O)C1)c1cccc(-c2nc(C)no2)c1,,Cl,O,,,test
US20130217709A1,CCOC(=O)[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)N1C[C@@H](NC(=O)OCc2ccccc2)[C@H](C(=O)O)C1,,C1CCOC1,O,[Li+].[OH-],,test
US20120059030A1,CC(=O)OC(C)=O.Oc1ccc(F)c(F)c1F>>CC(=O)Oc1ccc(F)c(F)c1F,,C1CCOC1,,CCN(CC)CC,,test
US20110207713A1,CC(C)(C)OC(=O)N1CCC(Cc2ccc3nc(Cl)nc(N4CCOCC4)c3n2)CC1>>Clc1nc(N2CCOCC2)c2nc(CC3CCNCC3)ccc2n1,,C1COCCO1,ClCCl,Cl,,test
US20110105462A1,CN.Cc1ccc(S(=O)(=O)OCC2COc3ccc(F)cc3O2)cc1>>CNCC1COc2ccc(F)cc2O1,,CC#N,,,,test
US20130053409A1,C=CC(=O)Oc1c(F)c(F)c(F)c(F)c1F.COc1cc(N2CCN(C)CC2)c(N)cc1Nc1nccc(-c2cnn3ccccc23)n1>>C=CC(=O)Nc1cc(Nc2nccc(-c3cnn4ccccc34)n2)c(OC)cc1N1CCN(C)CC1,,CN(C)C=O,ClCCl,,,test
US20150252038A1,C[C@@H]1CC[C@@H](Oc2cc(F)c(C(=O)OC(C)(C)C)cc2C2CC2)CN1C(=O)OCc1ccccc1>>C[C@@H]1CC[C@@H](Oc2cc(F)c(C(=O)OC(C)(C)C)cc2C2CC2)CN1,[Pd],CCOC(C)=O,,,,test
US20150376208A1,CC(C)(C)ON=O.Clc1ncc2c(n1)CCCC2>>O/N=C1\CCCc2cnc(Cl)nc21,,C1CCOC1,O,CC(C)(C)[O-].[K+],,test
US20030055085A1,CCN(CC)CC.N#Cc1cc(C(=O)Cl)cc([N+](=O)[O-])c1.N#Cc1cc(C(=O)O)cc([N+](=O)[O-])c1>>N#Cc1cc(-c2nc(-c3ccccn3)no2)cc([N+](=O)[O-])c1,,ClCCl,,,,test
US20050272778A1,COC(=O)c1c(O)cccc1OCCCCCNC(=O)[C@H](Cc1ccc(C2CC(=O)NS2(=O)=O)c(F)c1)NC(=O)OC(C)(C)C.O=C(O)C(F)(F)F>>COC(=O)c1c(O)cccc1OCCCCCNC(=O)[C@@H](N)Cc1ccc(C2CC(=O)NS2(=O)=O)c(F)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20080280933A1,CCOC(OCC)C(=N)OC.Nc1cc(F)c(F)cc1[N+](=O)[O-]>>CCOC(OCC)c1nc2cc(F)c(F)cc2[nH]1,[Pd],CO,,CC(=O)O,,test
US20060058522A1,BrCc1ccc(Br)cc1.CNCCOC>>COCCN(C)Cc1ccc(Br)cc1,,CN(C)C=O,,,,test
US03987047,BrBr.CC(=O)N1CCCc2nc3ccc(O)cc3c(C)c2C1>>CC(=O)N1CCCc2nc3ccc(O)c(Br)c3c(C)c2C1,,CC(=O)O,O,,,test
US04064273,Brc1ccccc1Br.CC(C)(C)c1cc(O)cc(C(C)(C)C)c1>>CC(C)(C)c1cc(Oc2ccc(Br)cc2)cc(C(C)(C)C)c1,[Cu],CC(=O)N(C)C,,[H-].[Na+],,test
US20140018533A1,CCOC(=O)CC(=O)CCl.COc1ccc(N=C=O)cc1>>CCOC(=O)C1=C(Nc2ccc(OC)cc2)OCC1=O,,CCOC(C)=O,CCOCC,CCN(CC)CC,,test
US20110136764A1,CN.COC(=O)c1cc(Br)ccc1N>>CNC(=O)c1cc(Br)ccc1N,,O,,,,test
US20090247577A1,CCOC(=O)C1(F)CN(C(=O)OC(C)(C)C)CC1Cc1ccccc1>>CC(C)(C)OC(=O)N1CC(Cc2ccccc2)C(F)(CO)C1,,C1CCOC1,,[BH4-].[Li+],,test
US20020019569A1,O=C(O)c1ccc(Cl)nc1.[Li]C>>CC(=O)c1ccc(Cl)nc1,,CCOCC,,,,test
US04436913,ClC1=NCCN1.Cn1ncc2cc(N)ccc21>>Cl.Cn1ncc2cc(NC3=NCCN3)ccc21,,C1CCOC1,CCOCC,,,test
US05712418,C[C@H](NC(=O)OCc1ccccc1)C(=O)O.Fc1nc(F)nc(F)n1>>C[C@H](NC(=O)OCc1ccccc1)C(=O)F,,ClCCl,,c1ccncc1,,test
US20150175617A1,COC(=O)c1cccc2[nH]c([C@@]3(C)CCCN3C(=O)OCc3ccccc3)cc12>>COC(=O)c1cccc2[nH]c([C@@]3(C)CCCN3)cc12,[Pd],CO,,[H][H],,test
US04139389,CC(C)(C)NS(=O)(=O)c1cc(N=Nc2ccc(S(=O)(=O)Cl)cc2)c2c(NS(C)(=O)=O)cccc2c1OC(=O)c1ccccc1.CCCCCCCCCCCCS(=O)(=O)c1cc(C(=O)N2CCC(CN)CC2)c([N+](=O)[O-])c(S(=O)(=O)CCCCCCCCCCCC)c1.Cl>>CCCCCCCCCCCCCCCCCCS(=O)(=O)c1cc(C(=O)O)c([N+](=O)[O-])cc1Cl,,CCN(CC)CC,,C1CCOC1,Cl,test
US20090163524A1,CC(C)(C)OC(=O)NC1(C(=O)O)CCN(c2ncnc3[nH]ccc23)CC1.N[C@@H](CCO)c1ccc(Br)cc1>>CC(C)(C)OC(=O)NC1(C(=O)N[C@@H](CCO)c2ccc(Br)cc2)CCN(c2ncnc3[nH]ccc23)CC1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090318431A1,CN1C(=O)OCc2cc(N3C[C@H](CN)OC3=O)ccc21.COC(=O)Cl>>COC(=O)NC[C@H]1CN(c2ccc3c(c2)COC(=O)N3C)C(=O)O1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090105259A1,CC(C)N=C=O.COC[C@H](O)CNCCCCNS(=O)(=O)c1ccc(Cl)cc1Cl>>COC[C@H](O)CN(CCCCNS(=O)(=O)c1ccc(Cl)cc1Cl)C(=O)NC(C)C,,ClC(Cl)Cl,,,,test
US04770695,Nc1ccc(Br)cc1F.O=[N+]([O-])O>>Nc1cc([N+](=O)[O-])c(Br)cc1F,,O=S(=O)(O)O,,,,test
US20150045399A1,CCOC(=O)CNN.O=C(CC(=O)C(F)(F)F)c1ccc(Br)s1>>CCOC(=O)Cn1nc(C(F)(F)F)cc1-c1ccc(Br)s1,,CO,,,,test
US05753679,O=C(Cl)c1ccc(Br)cc1[N+](=O)[O-].OC1CCN(Cc2ccccc2)CC1>>O=C(OC1CCN(Cc2ccccc2)CC1)c1ccc(Br)cc1[N+](=O)[O-],,Cc1ccccc1,,CCN(CC)CC,,test
US06130239,COC(=O)CCC#Cc1c([N+](=O)[O-])ccc2c1/C(=C/c1[nH]ccc1OC)C(=O)N2>>COC(=O)CCC#Cc1c(N)ccc2c1/C(=C/c1[nH]ccc1OC)C(=O)N2,[Zn],CO,O,[Cl-].[NH4+],,test
US20090082332A1,CCCCOc1nc(N)c2nc(OC)n(CCCBr)c2n1.Cl>>CCCCOc1nc(N)c2[nH]c(=O)n(CCCBr)c2n1.Cl,,C1COCCO1,CO,,,test
US20120142714A1,CCOc1ccc(C)c([N+](=O)[O-])c1.O=C1CCC(=O)N1Br>>CCOc1ccc(CBr)c([N+](=O)[O-])c1,,CCOC(C)=O,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20120094997A1,BrCc1cccc(CBr)c1.COC(=O)c1ccc2cc[nH]c(=O)c2c1>>COC(=O)c1ccc2ccn(Cc3cccc(CBr)c3)c(=O)c2c1,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070112023A1,Cl.Cl.O=C(Nc1ccc(-c2ccc([N+](=O)[O-])cc2)cc1)[C@H]1CN2CCC1CC2>>Cl.Cl.Nc1ccc(-c2ccc(NC(=O)[C@H]3CN4CCC3CC4)cc2)cc1,[Pd],CO,Cl,,,test
US04424231,C=CCc1c(OCCCOc2ccc(C(C)=O)c(O)c2CCC)ccc2oc(C(=O)OC)cc12>>C=CCc1c(OCCCOc2ccc(C(C)=O)c(O)c2CCC)ccc2oc(C(=O)O)cc12,,C1COCCO1,,[Na+].[OH-],,test
US20110318267A1,C=C(C)C(=O)OCCN(C)C.C=C(C)C(=O)OCCO>>C=C(C)C(=O)OCCN(C)C.C=C(C)C(=O)OCCO,,O,,,,test
US20090018054A1,BrC(Br)(Br)Br.COC(=O)c1ccc(-c2ccc(OC)c(-c3ccc(C(F)(F)F)cc3CO)c2)c(C)c1>>COC(=O)c1ccc(-c2ccc(OC)c(-c3ccc(C(F)(F)F)cc3CBr)c2)c(C)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110053940A1,C=CB1OC(C)(C)C(C)(C)O1.COC(=O)c1cc(Br)cc2ccccc12>>C=Cc1cc(C(=O)OC)c2ccccc2c1,,CCCO,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20040248854A1,CCOC(=O)COC/C=C\CN1C(=O)CCC[C@@H]1COC(C)OCC>>COC(=O)COC/C=C\CN1C(=O)CCC[C@@H]1CO,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20140045872A1,CCn1cc(C=C[N+](=O)[O-])c2ccccc21>>CCn1cc(CCN)c2ccccc21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130131068A1,FC(F)c1nnc2n1CCNC2.O=C(O)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F>>O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCn2c(nnc2C(F)F)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160021883A1,CC(C)c1ccccc1N=C=S.Nc1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1>>CC(C)c1ccccc1NC(=S)Nc1ccc(-c2ncn(-c3ccc(OC(F)(F)F)cc3)n2)cc1,,C1CCOC1,,,,test
US04348519,COC(=O)C1=C(O)c2sc3ccccc3c2S(=O)(=O)N1.COc1ccc(CBr)cc1>>COC(=O)C1=C(O)c2sc3ccccc3c2S(=O)(=O)N1Cc1ccc(OC)cc1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20050054648A1,COc1ccc(C(F)(F)F)cc1N=C=O.Nc1cccc(C2(Br)Cn3ccnc3C(n3ccnc3-c3ccncc3)=N2)c1>>COc1ccc(C(F)(F)F)cc1NC(=O)Nc1cccc(-c2cn3ccnc3c(-n3ccnc3-c3ccncc3)n2)c1,,ClCCl,,CN(C)C=O,,test
US20140045831A1,COC(=O)[C@@](C)(Oc1nc(NCc2ccc(OC)cc2OC)ccc1[N+](=O)[O-])c1ccccc1>>COc1ccc(CNc2ccc3c(n2)O[C@@](C)(c2ccccc2)C(=O)N3)c(OC)c1,[Fe],CC(=O)O,,,,test
US20100120806A1,O=[N+]([O-])c1cc(F)c(OCc2ccccc2)c(F)c1>>Nc1cc(F)c(O)c(F)c1,[Pd],CCO,,,,test
US06060484,NCC(c1ccccc1)c1ccccc1.O=C=Nc1ccccc1Cl>>O=C(NCC(c1ccccc1)c1ccccc1)Nc1ccccc1Cl,,CN(C)C=O,,,,test
US20120251551A1,N#Cc1ccc(Cl)nc1.OCc1c[nH]cn1>>N#Cc1ccc(-n2cnc(CO)c2)nc1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04888418,CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@H](N=[N+]=[N-])OC[C@H]1OC(C)=O.CCOC(C)=O>>CC(=O)N[C@@H]1OC[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O,[Pd],,,[H][H],,test
US20130150355A1,CC(C)(C)OC(=O)N1CCNCC1.COc1cnc(Cl)nc1>>COc1cnc(N2CCN(C(=O)OC(C)(C)C)CC2)nc1,,CN(C)C=O,,CCN(CC)CC,,test
US20070213336A1,CCCCCNC(=O)N(C)c1cccc(-c2ccc(/C=C/C(=O)OC)cc2OCc2ccccc2)c1>>CCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2O)c1,[Pd],CCOC(C)=O,CO,,,test
US20090306066A1,CC(C)(C)OC(=O)NN.Fc1c(Cl)nc(Cl)nc1Cl>>CC(C)(C)OC(=O)NNc1nc(Cl)nc(Cl)c1F,,C1CCOC1,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20100029650A1,CC(C)c1noc(N2CCC(COc3ccc(Br)nc3)CC2)n1.O=S(=O)(NCCO)c1ccc(B(O)O)cc1>>CC(C)c1noc(N2CCC(COc3ccc(-c4ccc(S(=O)(=O)NCCO)cc4)nc3)CC2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20080312226A1,CC(C)(C)OC(=O)N1CCN(c2nc(-c3ccccc3)cs2)CC1>>c1ccc(-c2csc(N3CCNCC3)n2)cc1,,CCOC(C)=O,,CCOCC,Cl,test
US20020156094A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NS(=O)(=O)CCc1ccccc1>>CC(C)(C)OC(=O)NS(=O)(=O)CCc1ccccc1,CN(C)c1ccccn1,ClCCl,,CCN(CC)CC,,test
US20130338169A1,COC(=O)C(C)Br.FC(F)(F)c1ccc(N2CCNCC2)nc1>>COC(=O)C(C)N1CCN(c2ccc(C(F)(F)F)cn2)CC1,,CO,,,,test
US20150166507A1,C#CCNC(=O)c1cccnc1Cl.COc1cc(N)cc(OC)c1>>C#CCNC(=O)c1cccnc1Nc1cc(OC)cc(OC)c1,,OCCO,,,,test
US05084463,CC(Cl)Cl.COc1ccc2c(ccc(C)[n+]2[O-])c1>>COc1ccc2nc(CCl)ccc2c1,,CC(Cl)Cl,,Cc1ccc(S(=O)(=O)Cl)cc1,,test
US20120214997A1,O[C@H](CCl)Cc1cc(F)c(F)cc1F>>Fc1cc(F)c(C[C@H]2CO2)cc1F,,CO,,[Na+].[OH-],,test
US20110257241A1,CCI.COC1(c2cccc(F)c2F)CCNC1>>CCN1CCC(OC)(c2cccc(F)c2F)C1,,O,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US20090118296A1,CCOC(OCC)OCC.NC(=NO)c1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1>>FC(F)(F)c1ccccc1OC1CCN(c2ccc(-c3ncon3)nn2)CC1,,C1CCOC1,,CCOCC,FB(F)F,test
US20050119292A1,Cc1cn(-c2ccc(N3C[C@H](CN)OC3=O)cc2F)nn1.Cc1ncn(-c2ccc(N3CC(CN=[N+]=[N-])OC3=O)cc2F)n1>>CN1C=NN(c2ccc(N3CC(CN)OC3=O)cc2F)C1,,ClCCl,,CO,,test
US20080318945A1,CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCN(C(=O)[C@@H](N)CO)CC1.O=S(=O)(Cl)c1ccc(Cl)cc1Cl>>CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCN(C(=O)[C@H](CO)NS(=O)(=O)c2ccc(Cl)cc2Cl)CC1,,ClCCl,,CCN(CC)CC,,test
US20140179666A1,C[C@@H]1CN(CC(=O)OCc2ccccc2)[C@@H](CN2CCOC2=O)CN1C(=O)OC(C)(C)C>>C[C@@H]1CN(CC(=O)O)[C@@H](CN2CCOC2=O)CN1C(=O)OC(C)(C)C,[Pd],,,,,test
US20030069297A1,Cc1c(C(=O)N2CCN(C)CC2)c[nH]c1C=O.O=C1Cc2c(cccc2-c2ccc(Cl)cc2)N1>>Cc1c(C(=O)N2CCN(C)CC2)c[nH]c1C=C1C(=O)Nc2cccc(-c3ccc(Cl)cc3)c21,C1CCNCC1,CCO,,,,test
US20100063013A1,COC(=O)[C@@H]1CSCC#C[C@](c2ccc(Br)cc2)(C(F)(F)F)N[C@@H](CC(C)(C)F)C(=O)N1>>CC(C)(F)C[C@@H]1N[C@@](c2ccc(Br)cc2)(C(F)(F)F)C#CCSC[C@@H](C(=O)O)NC1=O,,CO,COCCOC,Cl,[Li+].[OH-],test
US04820734,O=C1CCCC[C@H]1[C@@H](C[N+](=O)[O-])c1ccc(Cl)cc1>>NC[C@@H](c1ccc(Cl)cc1)[C@@H]1CCCC[C@@H]1O,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20090054435A1,CCCC(Br)C(=O)OCC.COc1ccc(C(=O)c2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)c(O)c1>>CCCC(Oc1cc(OC)ccc1C(=O)c1ccc(OCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20030207884A1,CCCCCCCCCCCCBr.Oc1ccccc1>>CCCCCCCCCCCCOc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020052512A1,COC(=O)c1ccc(C(=O)[O-])cc1Cl>>COC(=O)c1ccc(CO)cc1Cl,,C1CCOC1,,CCOC(C)=O,O,test
US20110144090A1,Brc1ccccc1.CCn1cc(CCN(C)C)c2c(O)cc(F)cc21>>CCn1cc(CCN(C)C)c2c(Oc3ccccc3)cc(F)cc21,[Cu]I,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20090221822A1,COC(=O)/C=C/c1cccc(F)c1NC(=O)Nc1cc(C(F)(F)F)ccc1OC>>COC(=O)CC1c2cccc(F)c2NC(=O)N1c1cc(C(F)(F)F)ccc1OC,,CC(C)=O,,,,test
US04102881,CCOC([O-])[O-].NNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=NC1>>Clc1ccc2c(c1)C(c1ccccc1)=NCc1nncn1-2,,ClC(Cl)Cl,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US20090163488A1,Cc1cc(C(=O)Cl)n(C)n1.Cc1ccc(N)cc1Oc1ccc2nc(NC(=O)C3CC3)nn2c1>>Cc1cc(C(=O)Nc2ccc(C)c(Oc3ccc4nc(NC(=O)C5CC5)nn4c3)c2)n(C)n1,,CC(=O)N(C)C,,,,test
US20100087456A1,CC1(C)OB(c2ccc(N)nc2)OC1(C)C.Cc1nc(N)nc2c1cc(Br)c(=O)n2[C@@H]1CCOC1>>Cc1nc(N)nc2c1cc(-c1ccc(N)nc1)c(=O)n2[C@@H]1CCOC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,Br,O=C([O-])[O-].[K+].[K+],test
US04179277,NC(=NO)c1nc(Cl)c(Cl)[nH]1.O=C(Cl)c1ccccc1>>NC(=NOC(=O)c1ccccc1)c1nc(Cl)c(Cl)[nH]1,,C1COCCO1,,CCN(CC)CC,O,test
US20160158207A1,CC(C)(C)OC(=O)N1CCc2[nH]nc(Br)c2C1>>Brc1n[nH]c2c1CNCC2,,ClCCl,,,,test
US04628115,CCCc1c(O)ccc(C(C)=O)c1O.N#CCCCCCCBr>>CCCc1c(OCCCCCCC#N)ccc(C(C)=O)c1O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04528114,CCCCCc1ccc(-c2ccc(C=C(Br)Br)cc2)cc1>>C#Cc1ccc(-c2ccc(CCCCC)cc2)cc1,,C1CCOC1,CCCCCC,O,[Li]CCCC,test
US05104889,CCOC(=O)Cc1csc(Oc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)n1>>CC(C)(C)c1cc(Oc2nc(CC(=O)O)cs2)cc(C(C)(C)C)c1O,,CCO,,O,[Na+].[OH-],test
US20100041684A1,CSc1cc(Oc2ccc(N)cc2)ncn1.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>CSc1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ncn1,,C1CCOC1,,,,test
US20090305998A1,COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(NOC3CCCCO3)=N2)n1>>COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3/C(=N/O)N2)n1,,C1COCCO1,,Cl,,test
US04268510,CC(=O)OC(C)=O.O=Cc1cc(O)ccc1[N+](=O)[O-]>>CC(=O)Oc1ccc([N+](=O)[O-])c(CO)c1,,O,,,,test
US20090048258A1,CCOC(=O)CCC(=O)c1ccc(OCC)c(OCC)c1.CO.COC([O-])[O-]>>CCOc1ccc(C(CCC(=O)OC)(OC)OC)cc1OCC,,CO,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US06617426B1,CCOP(=O)(Cl)OCC.CS(=O)(=O)c1ccccc1>>CCOP(=O)(CS(=O)(=O)c1ccccc1)OCC,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20080249079A1,CCN(C(C)C)C(C)C.Cc1cc(Nc2cc(C3CC3)[nH]n2)nc(Cl)n1.NCc1cc(-c2ccccc2)no1>>CC1(N)C=C(Nc2cc(C3CC3)[nH]n2)N=C(NCc2cc(-c3ccccc3)no2)N1,,CCCCO,,,,test
US20130338142A1,Brc1cn2ccnc2c(Br)n1.COc1cc(N)ccc1N1CCOCC1>>COc1cc(Nc2nc(Br)cn3ccnc23)ccc1N1CCOCC1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20130158025A1,CCOC(=O)CC(=O)c1ccc(OC)cc1.Cc1n[nH]c(N)c1-c1ccc(Cl)cc1>>COc1ccc(-c2cc(=O)[nH]c3c(-c4ccc(Cl)cc4)c(C)nn23)cc1,,c1ccncc1,,,,test
US20120214803A1,Nc1cccc2cccnc12.O=S(=O)(Cl)c1cccc(OC(F)(F)F)c1>>O=S(=O)(Nc1cccc2cccnc12)c1cccc(OC(F)(F)F)c1,CN(C)c1ccncc1,,,,,test
US20130150343A1,CC(C)(C)c1cc(NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCCCC5)n4c3)c3ccccc32)n(-c2cccc(OCCOC3CCCCO3)c2)n1.CS(=O)(=O)Cl>>CC(C)(C)c1cc(NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(N5CCCCC5)n4c3)c3ccccc32)n(-c2cccc(OCCOS(C)(=O)=O)c2)n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20130172312A1,Fc1cccc(Br)n1.OCC1CC1(F)F>>FC1(F)CC1COc1cccc(Br)n1,,C1COCCO1,CN(C)C=O,O,[H-].[Na+],test
US20120128686A1,CNC.COC(=O)c1sc2ncnc(Nc3ccc(F)cc3OC3CCOCC3)c2c1C>>Cc1c(C(=O)N(C)C)sc2ncnc(Nc3ccc(F)cc3OC3CCOCC3)c12,,C1CCOC1,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030105089A1,CC(=O)OC(C)=O.COC(=O)C(NC(=O)OCc1ccccc1)P(=O)(OC)OC>>COC(=O)C(NC(C)=O)P(=O)(OC)OC,[Pd],CO,,,,test
US20050176767A1,C=C[Sn](CCCC)(CCCC)CCCC.COC(=O)c1nc(OC)cc(Br)c1OCc1ccccc1>>C=Cc1cc(OC)nc(C(=O)OC)c1OCc1ccccc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,,,,test
US20130225554A1,CC(C)(C)OC(=O)N1CC(ONC(=O)[C@@H]2CC[C@@H]3CN2C(=O)N3OCc2ccccc2)C1>>CC(C)(C)OC(=O)N1CC(ONC(=O)[C@@H]2CC[C@@H]3CN2C(=O)N3O)C1,[Pd],CO,,[H][H],,test
US20100331312A1,CC(C)(C)[Si](C)(C)Cl.OCCc1ccc(-c2ccc3c(c2)CCNC3)cc1>>CC(C)(C)[Si](C)(C)OCCc1ccc(-c2ccc3c(c2)CCNC3)cc1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20110112070A1,CC(C)(C)C(=O)OCc1nc(C(=O)O)cs1>>O=C(O)c1csc(CO)n1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20020002284A1,O=C(CCl)CCl.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>O=C(CCl)C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Cl-],,C1CCOC1,CCOCC,,,test
US20040110763A1,CC(C)n1nc(-c2c(-c3ccccc3)nn3ccc(N4CCNCC4)cc23)ccc1=O.COC(=O)Cl>>COC(=O)N1CCN(c2ccn3nc(-c4ccccc4)c(-c4ccc(=O)n(C(C)C)n4)c3c2)CC1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20160129002A1,CC(C)(O)CN.FC(F)(F)COCc1cc(Cl)nc(Cl)n1>>CC(C)(O)CNc1cc(COCC(F)(F)F)nc(Cl)n1,,CC#N,CO,CCN(CC)CC,Cl,test
US20030216586A1,CC1(C)CCOc2ccccc21.ICI>>CC1(C)CCOc2c(I)cccc21,,CCOCC,O,CN(C)CCN(C)C,[Li]CCCC,test
US06284894B1,C=CCBr.Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>O=[N+]([O-])C=CCc1cccc([N+](=O)[O-])c1,,CC#N,,CC(C)(C)ON=O,,test
US20110201604A1,COC(CNC(=O)c1ccc2c(c1)nc(Nc1nc3ccc(Cl)cc3s1)n2C)OC>>Cn1c(Nc2nc3ccc(Cl)cc3s2)nc2cc(C(=O)NCC=O)ccc21,,C1COCCO1,Cl,,,test
US20030050298A1,CN(C)S(=O)(=O)c1c(Cl)ccc([N+](=O)[O-])c1O>>CN(C)S(=O)(=O)c1c(Cl)ccc(N)c1O,[Pd],CCOC(C)=O,,,,test
US20110076292A1,CC(C)n1ncnc1-c1cn2c(n1)-c1ccc(O)cc1OCC2.C[C@@H](OS(C)(=O)=O)C(N)=O>>CC(C)n1ncnc1-c1cn2c(n1)-c1ccc(O[C@@H](C)C(N)=O)cc1OCC2,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20070054923A1,CCOC(=O)CC(=O)OCC.O=c1oc(=O)n(Cc2ccccc2)c2ccc(F)cc12>>CCOC(=O)c1c(O)c2cc(F)ccc2n(Cc2ccccc2)c1=O,,CC(=O)N(C)C,,[H][H],[H-].[Na+],test
US20110212937A1,FC1(F)CCNCC1.Fc1ccc(C2CCc3c(Cl)nc(Cl)nc32)cc1>>Fc1ccc(C2CCc3c2nc(Cl)nc3N2CCC(F)(F)CC2)cc1,,CO,,,,test
US20150023990A1,CN.O=[N+]([O-])c1cnc2ccc(OCc3ccccc3)cc2c1Cl>>NCc1c([N+](=O)[O-])cnc2ccc(OCc3ccccc3)cc12,,O,,,,test
US20090030020A1,COC(=O)c1nc(SC)ncc1C#Cc1ccccc1Cl>>CSc1ncc2cc(-c3ccccc3Cl)oc(=O)c2n1,,ClCCl,O,O=C(O)C(F)(F)F,,test
US20060106048A1,COc1c(CC#N)c2c(c3c1OC(C)(C)C3)C(c1ccccc1)=NC(C)(C)C2.O=S(=O)(c1ccccc1)N(F)S(=O)(=O)c1ccccc1>>COc1c2c(c3c(c1C(F)C#N)CC(C)(C)N=C3c1ccccc1)CC(C)(C)O2,,C1CCOC1,,CCCCC,[Li]C(C)(C)C,test
US20080153836A1,CC(C)n1cccn1.CCCC[Sn](Cl)(CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)c1ccnn1C(C)C,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20080207654A1,CCCc1nc(CC)c(Oc2cc(F)ccc2F)c(=O)n1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCc1nc(CC)c(Oc2cc(F)ccc2F)c(=O)n1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20110015230A1,CC(C)Br.CCOC(C)=O.CN(C)C=O.O=C(O)c1ccc(C(F)(F)F)cc1O>>CC(C)OC(=O)c1ccc(C(F)(F)F)cc1OC(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030232832A1,C1CCOC1.COC(=O)c1ccn2nc(C=CN(C)C)n(Cc3ccccc3)c(=O)c12>>COC(=O)c1ccn2nc(C=O)n(Cc3ccccc3)c(=O)c12,,C1CCOC1,,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20110190280A1,CCc1nc(-c2ccc3ccn(S(=O)(=O)c4ccccc4)c3c2)c(-c2ccnc(Cl)n2)s1.CS(=O)(=O)CCN1CCC(Oc2ccc(N)cc2F)CC1>>CCc1nc(-c2ccc3ccn(S(=O)(=O)c4ccccc4)c3c2)c(-c2ccnc(Nc3ccc(OC4CCN(CCS(C)(=O)=O)CC4)c(F)c3)n2)s1,Cl,CC(C)O,,,,test
US20140350019A1,O=C(Nc1c(F)ccc(O)c1Cl)c1cc(-c2cccc(F)c2)ccc1F>>Oc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1Cl,,C1CCOC1,,,,test
US20150080393A1,CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4ccc(-c5ccccc5)cc4-n4ccc(C)n4)C(F)(F)F)nc(N)n3)CC2)CN1C(=O)OCc1ccccc1>>CCOC(=O)[C@@H]1CC2(CCN(c3cc(O[C@H](c4ccc(-c5ccccc5)cc4-n4ccc(C)n4)C(F)(F)F)nc(N)n3)CC2)CN1,[Pd],CCOC(C)=O,,,,test
US20160083370A1,Cc1ccc(S(=O)(=O)OCCCc2c[nH]c3ccc(C#N)cc23)cc1.Fc1cnc(N2CCNCC2)nc1>>N#Cc1ccc2[nH]cc(CCCN3CCN(c4ncc(F)cn4)CC3)c2c1,,CC#N,,[I-].[K+],,test
US20030130518A1,CCOCc1nc2cnc3ccccc3c2n1CCOCCNC(=O)OC(C)(C)C.O=C(OO)c1cccc(Cl)c1>>CCOCc1nc2c[n+]([O-])c3ccccc3c2n1CCOCCNC(=O)OC(C)(C)C,,ClC(Cl)Cl,,O,,test
US20060074111A1,CCCNc1cccc(-c2ccc(C(F)(F)F)cc2)c1.CCOC(=O)COc1ccc(CBr)cc1C>>CCCN(Cc1ccc(OCC(=O)OCC)c(C)c1)c1cccc(-c2ccc(C(F)(F)F)cc2)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20080261977A1,CON(C)C(=O)c1cnc(Nc2ccc(Cl)cc2Cl)nc1C(F)(F)F.[Li]C>>CC(=O)c1cnc(Nc2ccc(Cl)cc2Cl)nc1C(F)(F)F,,C1CCOC1,,,,test
US04409018,CCN=C=S.O=C1C2=C(CCCC2)C(S)N1c1ccc(Br)cc1F>>CCNC(=S)SC1C2=C(CCCC2)C(=O)N1c1ccc(Br)cc1F,CCN(CC)CC,ClCCl,,,,test
US06153742,O=C(O)Cc1ccc(O)c(Cl)c1.Oc1cc(Cl)c(Cl)cc1Cl>>O=C(Cc1ccc(O)c(Cl)c1)Oc1cc(Cl)c(Cl)cc1Cl,,CCOC(C)=O,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20040133008A1,Cc1ccc(C)n1-c1ccn(CCO)n1.O=[N+]([O-])c1ccc(F)cc1>>Cc1ccc(C)n1-c1ccn(CCOc2ccc([N+](=O)[O-])cc2)n1,,C1CCOC1,,CCOC(C)=O,CC(C)(C)[O-].[K+],test
US04956371,COC(=O)Cc1ccc(OC)c(OC)c1.Cc1cccc(CCN)c1>>COc1ccc(CNCCc2cccc(C)c2)cc1OC,,CO,,,,test
US05006570,CC1Cc2cc(S(=O)(=O)Cl)cc(C(=O)O)c2O1.CN>>CNS(=O)(=O)c1cc2c(c(C(=O)O)c1)OC(C)C2,,O,,[Na+].[OH-],,test
US20060069088A1,CCOC(=O)c1cccc(C2CCN(C(=O)OC(C)(C)C)C(=O)C2)c1.CI>>CCOC(=O)c1cccc(C2CCN(C(=O)OC(C)(C)C)C(=O)C2C)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20030055246A1,CC(C)(C)[Si](C)(C)OCCc1ccncc1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)[Si](C)(C)OCCc1cc[n+]([O-])cc1,,ClCCl,,,,test
US20140163026A1,BrP(Br)Br.CN(C)c1cc(CO)c(Cl)cc1Br>>CN(C)c1cc(CBr)c(Cl)cc1Br,,ClCCl,,,,test
US05097013,CC(C)C[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)O>>CC(C)C[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)O,,CS(C)=O,,C1CCNCC1,CC(=O)O,test
US20030105132A1,COCC1OC(=O)C2(CCCC2)CC1C(=O)OC(C)(C)C>>COC/C=C(\CC1(C(=O)O)CCCC1)C(=O)OC(C)(C)C,,Cc1ccccc1,,C1CCC2=NCCCN2CC1,,test
US20110166116A1,CC(C)OC(=O)N1CCC(ON=C2CCN(c3cc(F)c(CC(=O)OC(C)(C)C)cc3F)CC2)CC1>>CC(C)OC(=O)N1CCC(ON=C2CCN(c3cc(F)c(CC(=O)O)cc3F)CC2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130178629A1,COC(=O)c1c(C(=O)OC)c2n(c1C)Cc1c(c3ccccc3n1C)C2>>Cc1c(CO)c(CO)c2n1Cc1c(c3ccccc3n1C)C2,,CCOCC,ClCCl,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06265415B1,Cc1cnc([N+](=O)[O-])c(OCc2c(C)cccc2C)c1>>Cc1cnc(N)c(OCc2c(C)cccc2C)c1,[Fe],CCO,,Cl,O,test
US06121308,Cc1cc(C)c2ccc(N)cc2n1.O=C1OC(=O)c2ccccc21>>Cc1cc(C)c2ccc(N3C(=O)c4ccccc4C3=O)cc2n1,,CC(=O)O,,,,test
US20050245563A1,CC(C)(C)OC(=O)CC(=O)O.O=C1c2ccccc2C(=O)N1CCCNc1ccc(Cl)cc1>>CC(C)(C)OC(=O)CC(=O)N(CCCN1C(=O)c2ccccc2C1=O)c1ccc(Cl)cc1,,ClCCl,,CCN=C=NCCCN(C)C,,test
US20160122359A1,BrCc1ccccc1.C[C@@H](OCc1ccccc1)[C@H](NC(=O)OC(C)(C)C)C(=O)O>>C[C@@H](OCc1ccccc1)[C@H](NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090042874A1,COc1c(Cl)cc(CO)c(F)c1[N+](=O)[O-].O=C1CCC(=O)N1Br>>COc1c(Cl)cc(CBr)c(F)c1[N+](=O)[O-],,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20150031674A1,Cc1ccc(S(=O)(=O)OCCNC(=O)OC(C)(C)C)cc1.OCCS>>CC(C)(C)OC(=O)NCCSCCO,,Cc1ccccc1,,C1CCC2=NCCCN2CC1,,test
US05428168,COC(=O)CCC(=O)c1ccc(Cl)cc1>>COC(=O)CCC(O)c1ccc(Cl)cc1,,CO,,[BH4-].[Na+],,test
US20140094474A1,CCOC(=O)c1cc(C(=O)NC2CC2)on1>>O=C(O)c1cc(C(=O)NC2CC2)on1,,CCO,,[Na+].[OH-],,test
US20040254214A1,CCOc1cc(C(O)Cc2c(Cl)cncc2Cl)ccc1OC.COC(=O)c1c(CBr)cccc1NC(=O)C1CC1.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>CCOc1cc(C(Cc2c(Cl)cncc2Cl)N2Cc3cccc(NC(=O)C4CC4)c3C2=O)ccc1OC,,CN(C)C=O,O,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120258946A1,COc1ccc(Cl)cc1N.O=N[O-]>>COc1ccc(Cl)cc1NN,,Cl,O,Cl[Sn]Cl,,test
US20120122930A1,N.O=C(OCc1ccccc1)c1cc([N+](=O)[O-])c(F)cc1F>>Nc1cc(F)c(C(=O)OCc2ccccc2)cc1[N+](=O)[O-],,C1CCOC1,,O,,test
US20120190689A1,CC1(C)CO1.O=C(c1ccccc1)N1CCNCC1>>CC(C)(O)CN1CCN(C(=O)c2ccccc2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130338132A1,CI.COC(=O)C(C)Cc1ccc(C(=O)OC(C)(C)C)s1>>COC(=O)C(C)(C)Cc1ccc(C(=O)OC(C)(C)C)s1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20030162961A1,CC1CN1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)N2CC2C)cc1,,[K+],[OH-],,,test
US05866612,Br.Br.CCCCOC(=O)NCC#CCNC(=N)CF>>Br.Br.N=C(CF)NCC#CCN,,CC(=O)O,,,,test
US20040063707A1,CC(=N)NO.COC(=O)c1cn2nc[nH]c(=O)c2c1C(C)C>>Cc1noc(-c2cn3nc[nH]c(=O)c3c2C(C)C)n1,,C1CCOC1,,[H-].[Na+],,test
US06281363B1,CC(C)C[C@@H](C(=O)NN1C(=O)N[C@@H](C(C)C)C1=O)[C@H](CNC(=O)c1ccccc1)C(=O)NOC1CCCCO1>>CC(C)C[C@@H](C(=O)NN1C(=O)N[C@@H](C(C)C)C1=O)[C@H](CNC(=O)c1ccccc1)C(=O)NO,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20070244159A1,CC(=O)O.CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc2n1CCN=[N+]=[N-]>>CC(=O)NCCn1c(C(C)(C)C)cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)ccc21,[Pd],,,CO,,test
US20140080816A1,CO.O=C(O)C1CCCN1>>COC(=O)C1CCCN1,,O=S(Cl)Cl,,,,test
US20020183319A1,Cc1cc(C(=O)O)[nH]c1C=O.O=C1Cc2c(ncnc2Nc2ccc(F)c(Cl)c2)N1>>Cc1cc(C(=O)O)[nH]c1C=C1C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c21,C1CCNCC1,CCO,,,,test
US04383113,COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(C)cc(OC)n1>>COc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)O)n1,,CCO,O,Cl,[K+].[OH-],test
US20110166137A1,BrCCCBr.CNc1nccc(-c2cc(N)c3cc(OC)ccc3c2)n1>>CNc1nccc(-c2cc(NCCCBr)c3cc(OC)ccc3c2)n1,,CC#N,,CCN(C(C)C)C(C)C,,test
US04843165,CO.O=C(O)C1CCc2cc(O)ccc21>>COC(=O)C1CCc2cc(O)ccc21,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090221555A1,CCN1CC(N2CCOCC2)COc2ccc([N+](=O)[O-])cc21>>CCN1CC(N2CCOCC2)COc2ccc(N)cc21,[Pd],CCO,,,,test
US20030060466A1,N#Cc1c(Cl)nc(NC2CC2)nc1NCCO.c1ccc(N2CCNCC2)cc1>>N#Cc1c(NCCO)nc(NC2CC2)nc1N1CCN(c2ccccc2)CC1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US07247645B2,C=C1CC(=O)O1.OCCCC(c1ccccc1)c1ccccc1>>CC(=O)CC(=O)OCCCC(c1ccccc1)c1ccccc1,,Cc1ccccc1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20110183978A1,Fc1ccc(-c2ccn(C3CC3)n2)cc1.O=C1CCC(=O)N1Br>>Fc1ccc(-c2nn(C3CC3)cc2Br)cc1,,ClCCl,,O,,test
US20120171245A1,CCOC(=O)C(=O)N(C(=O)OC(C)(C)C)C1CC2CC(C(=O)OC)C1C2>>CC(C)(C)OC(=O)NC1CC2CC(C(=O)O)C1C2,,CO,,Cl,[Na+].[OH-],test
US20130272978A1,CCCCCCCBr.CCOC1(CO)COC(CO)(OCC)CO1.Cc1ccccc1>>CCCCCCCOCC1(OCC)COC(COCCCCCCC)(OCC)CO1,,Cc1ccccc1,,O,[K+].[OH-],test
US20130116431A1,CC(C)c1cc(-c2n[nH]c(=O)n2C(C)C)c(O)cc1O.COCOc1cc(OCOC)c(C(C)C)cc1-c1nnc(S(C)(=O)=O)n1C(C)C>>CC(C)c1cc(-c2nnc(S(C)(=O)=O)n2C(C)C)c(O)cc1O,,CO,,Cl,O=C([O-])O.[Na+],test
US20130102776A1,COc1ccc2c(c1OC1CCN(C(=O)OC(C)(C)C)CC1)O/C(=C\c1n[nH]c3ccccc13)C2=O>>COc1ccc2c(c1OC1CCNCC1)O/C(=C\c1n[nH]c3ccccc13)C2=O,,C1COCCO1,ClCCl,Cl,,test
US20110118262A1,COC(=O)c1ccc(C2CCN(C(=O)c3ccco3)CC2)c(C(F)(F)F)c1>>O=C(O)c1ccc(C2CCN(C(=O)c3ccco3)CC2)c(C(F)(F)F)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20120035159A1,C=CCN(C[C@@H](C)NS(=O)(=O)c1ccccc1[N+](=O)[O-])C(=O)OC(C)(C)C.C=CCO>>C=CCN(C[C@@H](C)N(CC=C)S(=O)(=O)c1ccccc1[N+](=O)[O-])C(=O)OC(C)(C)C,,C1CCOC1,O,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05155122,CC(C)(C)c1cc(-c2nnc(S(C)(=O)=O)s2)cc(C(C)(C)C)c1O.NN>>CC(C)(C)c1cc(-c2nnc(NN)s2)cc(C(C)(C)C)c1O,,CC(C)O,,,,test
US04560690,CCCc1ccc(C=C(C#N)C(=O)OCC)cc1>>CCCc1ccc(CC(C#N)C(=O)OC)cc1,,CO,,Cl,[Mg],test
US20160002248A1,CC(C)(C)OC(=O)c1cn(CC(F)CCc2cc3cc(-c4ccccc4F)[nH]c3nn2)nn1>>O=C(O)c1cn(CC(F)CCc2cc3cc(-c4ccccc4F)[nH]c3nn2)nn1,,C1COCCO1,Cl,,,test
US04595521,CCCc1ccc(=O)[nH]n1.O=P(Br)(Br)Br>>CCCc1ccc(Br)nn1,,Cc1ccccc1,,O,O=C([O-])O.[Na+],test
US20130158031A1,C[Si](C)(C)C#Cc1ccc(-n2ncnc2-c2ccncc2)cc1>>C#Cc1ccc(-n2ncnc2-c2ccncc2)cc1,,O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US03951976,C=CCNCCC=O.CS(=O)(=O)c1nnc(N=C=O)s1>>C=CCN(CCC=O)C(=O)Nc1nnc(S(C)(=O)=O)s1,,c1ccccc1,,,,test
US20160002228A1,CC(C)n1nc(I)cc1C1CCNCC1.N#CCBr>>CC(C)n1nc(I)cc1C1CCN(CC#N)CC1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080255085A1,COC(=O)c1cccc(-c2nc3cccnc3[nH]2)c1.O=C(OO)c1cccc(Cl)c1>>COC(=O)c1cccc(-c2nc3c(Cl)ccnc3[nH]2)c1,,CC(=O)O,,,,test
US20030149016A1,NCc1ncn2ccsc12.O=C(Cl)OCc1ccc([N+](=O)[O-])cc1>>O=C(NCc1ncn2ccsc12)OCc1ccc([N+](=O)[O-])cc1,,C1CCOC1,O,[Na+].[OH-],,test
US05763489,CCOC(=O)COc1cccc2c1CCCC2CO.NN(c1ccccc1)c1ccccc1.O=C(Cl)Cl>>CCOC(=O)COc1cccc2c1CCCC2COC(=O)NN(c1ccccc1)c1ccccc1,,ClCCl,,Cl,c1ccncc1,test
US20040204450A1,CCOC(=O)N1c2ccc(C(F)(F)F)cc2C(C(OS(C)(=O)=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1CC.[N-]=[N+]=[N-]>>CCOC(=O)N1c2ccc(C(F)(F)F)cc2C(C(N=[N+]=[N-])c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1CC,,CCOC(C)=O,,CN(C)C=O,,test
US04048191,Cn1c(CC#N)cc(Br)c1C(=O)c1ccc(Cl)cc1.O.[OH-]>>Cn1c(CC(=O)O)cc(Br)c1C(=O)c1ccc(Cl)cc1,,CCO,,Cl,,test
US04929741,C#CCOC(C)OCC.Cc1ccc(C=O)cc1>>CCOC(C)OCC#CC(O)c1ccc(C)cc1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20090275624A1,COc1ccc(CN)cc1.Cc1nc2c(s1)C(=O)C=C(NCCCBr)C2=O>>COc1ccc(CNCCCNC2=CC(=O)c3sc(C)nc3C2=O)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20150087663A1,CC[C@H](N)c1nc2ccccc2c(=O)n1-c1ccccc1F.Cc1nnc(-c2c(N)ncnc2Cl)o1>>CC[C@H](Nc1ncnc(N)c1-c1nnc(C)o1)c1nc2ccccc2c(=O)n1-c1ccccc1F,,CCCCO,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US07714010B2,CN1C(=O)C2(CC2)c2cc(N)c([N+](=O)[O-])cc21>>CN1C(=O)C2(CC2)c2cc(N)c(N)cc21,[Pd],CO,Cl,,,test
US20040077557A1,COC(=O)CCl.c1ccc(-c2c[nH]cn2)cc1>>COC(=O)Cn1cnc(-c2ccccc2)c1,,CCOCC,CN(C)C=O,[H-].[Na+],,test
US20110034452A1,CCN.CNc1nnc2c(C)c(C)c(C(=O)OC)nn12>>CCNC(=O)c1nn2c(NC)nnc2c(C)c1C,,CO,,Cl,,test
US20060270646A1,CN(C)C(=O)n1cc(-c2cnco2)c2cc(Br)cnc21>>Brc1cnc2[nH]cc(-c3cnco3)c2c1,,CCO,,[Na+].[OH-],,test
US20090318431A1,CN1C(=O)OCCc2cc(NC[C@@H](O)CNC(=O)OC(C)(C)C)ccc21.O=C(n1ccnc1)n1ccnc1>>CN1C(=O)OCCc2cc(N3C[C@H](CNC(=O)OC(C)(C)C)OC3=O)ccc21,,CC#N,,,,test
US20060100246A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1CCCC(c2cc(-c3c(O)cccc3OCC3CC3)nc(N)c2CN)C1>>CC(=O)NCc1c(C2CCCN(C(=O)OC(C)(C)C)C2)cc(-c2c(O)cccc2OCC2CC2)nc1N,,C1CCOC1,,CCN(CC)CC,,test
US03948943,CCCCCCCCCCCCN.O=C(O)CNC(=O)c1ccccc1>>CCCCCCCCCCCCNC(=O)CNC(=O)c1ccccc1,,CCOC(C)=O,,C,,test
US05750540,CC(C)=CCCN1CCC(NC(=O)[C@](O)(c2ccccc2)C2CCC2)CC1.O=C(O)/C=C/C(=O)O>>CC(C)=CCCN1CCC(NC(=O)[C@](O)(c2ccccc2)C2CCC2)CC1.O=C(O)/C=C/C(=O)O,,CCO,,,,test
US20140128372A1,CCOC(=O)C(Cl)C(C)=O.Nc1ncccc1OCc1ccccc1>>CCOC(=O)c1c(C)nc2c(OCc3ccccc3)cccn12,,CCO,,,,test
US05321029,BrCC1CC1.CC(=O)Cn1cnc2c1c(=O)[nH]c(=O)n2Cc1ccccc1>>CC(=O)Cn1cnc2c1c(=O)n(CC1CC1)c(=O)n2Cc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160095844A1,CI.Cc1cnc(-c2ccc3c(c2)N(C)C(=O)C3(C)C)[nH]1>>Cc1cn(C)c(-c2ccc3c(c2)N(C)C(=O)C3(C)C)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150210734A1,CC(Cl)C(N)=O.C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(F)c1>>CC(Oc1ccc2c(c1)CC[C@H]1[C@@H]3CC=C(c4cncc(F)c4)[C@@]3(C)CC[C@H]21)C(N)=O,,CS(C)=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US05952306,CCOC(=O)C[C@@H](CCc1c[nH]c2ccccc12)NC(=O)CN(C(=O)CCCc1ccnc(C(=O)OC(C)(C)C)c1N)C1CC1>>CC(C)(C)OC(=O)c1nccc(CCCC(=O)N(CC(=O)N[C@H](CCc2c[nH]c3ccccc23)CC(=O)O)C2CC2)c1N,,CCO,CCOC(C)=O,[Na+].[OH-],,test
US20040092582A1,CSc1ccc(C#N)cc1.O=C(OO)c1cccc(Cl)c1>>CS(=O)(=O)c1ccc(C#N)cc1,,ClCCl,,[Na+].[OH-],,test
US20060030613A1,CC(C)(C)c1ccc(CNCCNc2ccccc2)cc1.O=C(O)c1cc(Cl)cc2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCNc2ccccc2)C(=O)c2cc(Cl)cc3cc[nH]c23)cc1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20130158006A1,CC1(C)Oc2cc([N+](=O)[O-])c(Cl)cc2NC1=O.CI>>CN1C(=O)C(C)(C)Oc2cc([N+](=O)[O-])c(Cl)cc21,,CN(C)C=O,,O,[H-].[Na+],test
US20150322056A1,BrBr.COc1cc(-c2ccco2)ccn1>>COc1cc(-c2ccc(Br)o2)ccn1,,ClC(Cl)Cl,,,,test
US20100234364A1,Nc1cc(Cl)ccc1C(=O)N1CCOCC1.O=S(=O)(Cl)c1ccc(Cl)c(C(F)(F)F)c1>>O=C(c1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1)N1CCOCC1,,CCOC(C)=O,c1ccncc1,,,test
US20040063170A1,CC(=O)OC[C@H]1O[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.CCOC(=O)/C=C/c1ccc(Cc2ccccc2O)cc1>>CCOC(=O)/C=C/c1ccc(Cc2ccccc2O[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)cc1,,Cc1ccccc1,ClCCl,,,test
US20080269293A1,COC(=O)C1=NN(c2ccccc2)C(=O)C1.O=[N+]([O-])c1ccccc1F>>COC(=O)c1cc(Oc2ccccc2[N+](=O)[O-])n(-c2ccccc2)n1,,CCOC(C)=O,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],test
US04271170,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(Cc2cccnc2)cc1>>COC(=O)/C=C/c1ccc(Cc2cccnc2)cc1,,ClC(Cl)Cl,,,,test
US20070249649A1,CC1CCNCC1.O=[N+]([O-])c1ccc(Br)cc1F>>CC1CCN(c2cc(Br)ccc2[N+](=O)[O-])CC1,,O,,,,test
US20130261114A1,C#Cc1ccccc1.O=C(c1ccccc1)C1CN2CCC1CC2>>OC(C#Cc1ccccc1)(c1ccccc1)C1CN2CCC1CC2,,C1CCOC1,,[Li]CCCC,,test
US05420275,COC(=O)c1c(OC)nc(C)c([N+](=O)[O-])c1C(=O)OC>>COC(=O)c1c(OC)nc(C)c(N)c1C(=O)OC,[Pd],CCOC(C)=O,,,,test
US20040082571A1,O=C1CCC(=O)N1Cl.c1csc(-c2cc[nH]n2)c1>>Clc1c[nH]nc1-c1cccs1,,CN(C)C=O,,,,test
US20080139558A1,Cc1ncsc1-c1cc2ccccc2n1C(=O)OC(C)(C)C>>Cc1ncsc1-c1cc2ccccc2[nH]1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050043388A1,COC(=O)CCCBr.O=C1Nc2ccc(I)cc2C1=O>>COC(=O)CCCN1C(=O)C(=O)c2cc(I)ccc21,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20070173501A1,CC1(C)O/C(=C2/C(=O)Nc3cc(F)ccc32)C=C1Br.O=Cc1cc(B(O)O)cs1>>CC1(C)O/C(=C2/C(=O)Nc3cc(F)ccc32)C=C1c1csc(C=O)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20090318690A1,COCOc1cc(OCC2CC2)c(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1C(C)=O>>CC(=O)c1cc(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(OCC2CC2)cc1O,,C1CCOC1,,Cl,,test
US20070032489A1,CC#N.COc1ncc(-c2cccc(C#N)c2)c2ccccc12>>Cc1[nH]c(=O)c2ccccc2c1-c1cccc(C#N)c1,,CC#N,O,C[Si](C)(C)Cl,[I-].[Na+],test
US20120010207A1,Cc1ccc(OC(=O)c2cc(Cl)c(F)cc2F)cc1.Oc1ccc(Cl)c(Cl)c1>>Cc1ccc(OC(=O)c2cc(Cl)c(Oc3ccc(Cl)c(Cl)c3)cc2F)cc1,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20070259864A1,CN(C)C(=O)Cl.N#Cc1ccc(OCCNCCO)cc1>>CN(C)C(=O)N(CCO)CCOc1ccc(C#N)cc1,,ClCCl,O,CCN(CC)CC,,test
US20150011546A1,COc1ccc(CNC(C)C2COCCO2)cc1>>CC(N)C1COCCO1,[Pd],CO,,,,test
US20160158207A1,CC(C)(C)OC(=O)N1CCc2[nH]nc(Br)c2C1.CS(=O)(=O)OC1CCOC1>>CC(C)(C)OC(=O)N1CCc2c(c(Br)nn2C2CCOC2)C1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070021405A1,CCOC(=O)COC(=O)Oc1ccccc1.c1ccc2cc(CC3CCNCC3)ccc2c1>>CCOC(=O)COC(=O)N1CCC(Cc2ccc3ccccc3c2)CC1,,CC#N,Cc1ccccc1,,,test
US20140018371A1,CC(C)(C)OC(=O)N1CCC(COC2CCC(c3ccc(S(C)(=O)=O)cc3)CC2)CC1.Cl>>CS(=O)(=O)c1ccc(C2CCC(OCC3CCNCC3)CC2)cc1.Cl,,C1COCCO1,,,,test
US05208247,CCCCCCCCCCCCCCOc1ccc(CN)cc1.CCN(CC)CC.O=C(Cl)c1cccnc1>>CCCCCCCCCCCCCCOc1ccc(CNC(=O)c2ccccc2)cc1,,ClCCl,,Cl,O=C([O-])O.[Na+],test
US20040164272A1,C=CC(=O)OCCCCCCI.CN(C)c1ccc(N=Nc2ccc(N=Nc3ccc(O)c4ccccc34)cc2)c2ccccc12>>C=CC(=O)OCCCCCCOc1ccc(N=Nc2ccc(N=Nc3ccc(N(C)C)c4ccccc34)cc2)c2ccccc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100311744A1,COc1ccc2c(c1)c(CO)nn2Cc1ccccc1.O=S(Cl)Cl>>COc1ccc2c(c1)c(CCl)nn2Cc1ccccc1,,ClC(Cl)Cl,,,,test
US20140135320A1,COCOc1c(Br)cc(C(C)(C)C)cc1C=O.OB(O)c1ccc(C(F)(F)F)nc1>>COCOc1c(C=O)cc(C(C)(C)C)cc1-c1ccc(C(F)(F)F)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20060079536A1,Cc1ccc(C(C)(C)C(=O)c2cnn3c2N(Cc2ccccc2)C(c2ccccc2)CC3(C)C)cc1>>Cc1ccc(C(C)(C)C(=O)c2cnn3c2NC(c2ccccc2)CC3(C)C)cc1,[Pd],C1CCOC1,,CCO,[H][H],test
US05155117,Cc1ccc(B(O)O)cc1.N#Cc1ncccc1Br>>Cc1ccc(-c2cccnc2C#N)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US04831151,Cc1n(N=Cc2ccc(N(C)C)cc2)cc[n+]1N.O=Cc1ccc([N+](=O)[O-])cc1.[Cl-]>>Cc1n(N=Cc2ccc([N+](=O)[O-])cc2)cc[n+]1N=Cc1ccc(N(C)C)cc1.[Cl-],,CC(=O)O,,,,test
US20080009486A1,C#C[Si](C)(C)C.Nc1ccc(I)cc1C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12>>C#Cc1ccc(N)c(C2NC(=O)CC(c3cccc(Cl)c3)C23C(=O)Nc2cc(Cl)ccc23)c1,[Cu]I,C1CCOC1,CO,CCN(CC)CC,[Na+].[OH-],test
US20050148624A1,CCCCB(O)O.COC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccccc1>>CCCCc1ccc2c(=O)n(Cc3ccccc3)c(C(=O)OC)c(-c3ccccc3)c2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,O,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20030207875A1,CCCCC(Br)C(=O)OCC.CN(C)C=O.COc1nc(N)c(Cl)cc1C(=O)NCC1CCNCC1>>CCCCC(C(=O)NC)N1CCC(CNC(=O)c2cc(Cl)c(N)[nH]c2=O)CC1,,CN(C)C=O,O,CCN(CC)CC,[I-].[Na+],test
US20160145240A1,COc1cc(OC)c(Cl)c(Nc2nc3ccccc3n2-c2cc(Cl)ncn2)c1Cl.Nc1ccc(CN2CCN(CC3CCCCC3)CC2)cc1>>COc1cc(OC)c(Cl)c(Nc2nc3ccccc3n2-c2cc(Nc3ccc(CN4CCN(CC5CCCCC5)CC4)cc3)ncn2)c1Cl,,C1COCCO1,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20050130989A1,CC(C)(C)OC(=O)N1CCN(c2cccc(C(=O)O)c2)CC1.CN>>CNC(=O)c1cccc(N2CCN(C(=O)OC(C)(C)C)CC2)c1,CN(C)C=O,C1COCCO1,ClCCl,O=C(Cl)C(=O)Cl,,test
US20090018104A1,CCOC(=O)c1cc(-c2ccc(OC)c(C#N)c2)ns1>>CCOC(=O)c1cc(-c2ccc(O)c(C#N)c2)ns1,,ClCCl,,BrB(Br)Br,,test
US20050209197A1,CCC(=O)C(=O)[O-].CO.Nc1ccc(C=O)c(N)c1>>COC(=O)c1ccc2ccc(N)cc2n1,,CO,,C1CCNCC1,,test
US03953506,NC1CCCc2ccccc21.O=C(O)CC[C@@H](NC(=O)c1ccccc1)C(=O)O>>N[C@H]1CCCc2ccccc21.O=C(O)CC[C@@H](NC(=O)c1ccccc1)C(=O)O,,O,,CC(=O)O,,test
US20090082310A1,CC(=O)Cl.CC(C)c1cc(Oc2c(Cl)cc(-n3nc(C#N)c(=O)[nH]c3=O)cc2Cl)nn(CO)c1=O>>CC(=O)OCn1nc(Oc2c(Cl)cc(-n3nc(C#N)c(=O)[nH]c3=O)cc2Cl)cc(C(C)C)c1=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20070072813A1,Cc1c(Cc2ccc(OCc3ccccc3)cc2F)c(O[C@@]2(O)O[C@H](COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)nn1C(C)C>>Cc1c(Cc2ccc(O)cc2F)c(O[C@@]2(O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)nn1C(C)C,[Pd],CCO,,,,test
US20050272702A1,CC1(C)OC(=O)Nc2ccc(-c3ccc(C#N)[nH]3)cc21.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC1(C)OC(=S)Nc2ccc(-c3ccc(C#N)[nH]3)cc21,,CC#N,,COCCOC,,test
US20090036492A1,CCc1cc(CC)c(C=O)c(CC)c1.COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C>>CCc1cc(CC)c(CNC(=O)c2c(OC)cc(O)c3c2OC2=CC(O)=C(C(C)=O)C(=O)[C@]23C)c(CC)c1,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20080275069A1,N#Cc1ncc(Br)cc1[N+](=O)[O-].O=S(=O)(O)O>>NC(=O)c1ncc(Br)cc1[N+](=O)[O-],,O=S(=O)(O)O,,O,,test
US20100298324A1,Nc1ncc(Cl)s1.O=C(NCc1cccc(Cl)c1)c1ccc(C(=O)[O-])c(N=C=S)c1>>O=C(NCc1cccc(Cl)c1)c1ccc2c(=O)n(-c3ncc(Cl)s3)c(=S)[nH]c2c1,,CS(C)=O,,[H-].[Na+],,test
US05559131,CCNC1CCN(C(=O)OCc2ccccc2)CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCN(C(=O)C(F)(F)F)C1CCN(C(=O)OCc2ccccc2)CC1,,ClCCl,,CCN(CC)CC,,test
US20130096121A1,COCC[C@@H]1[C@H]2C[C@@H](C[C@H]1C=O)C2(C)C>>COCC[C@@H]1[C@H]2C[C@@H](C[C@H]1CO)C2(C)C,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080045602A1,CC(C)NC(C)C.Cc1ccc(OS(=O)(=O)c2ccccc2)c(-c2cccc(S(=O)(=O)[O-])c2CCCc2ccccc2)c1>>Cc1ccc(OS(=O)(=O)c2ccccc2)c(C(CCN(C(C)C)C(C)C)c2ccccc2)c1,,CC#N,,[I-].[Na+],,test
US04871732,CSC1=NCCN1C(=O)c1ccccc1F.NN1CCCCCC1>>O=C1c2ccccc2N(N2CCCCCC2)C2=NCCN12,,O,,,,test
US04757080,CC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(=O)OCCCCCCN1C(=O)c2ccccc2C1=O.COC(=O)/C=C(/C)N>>COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCCCCN2C(=O)c3ccccc3C2=O)C1c1cccc([N+](=O)[O-])c1,,CC(C)O,,,,test
US20100130739A1,Cc1nc(NCC(=O)N(C)C2CCN(Cc3ccccc3)CC2)nc(C)c1[N+](=O)[O-]>>Cc1nc(NCC(=O)N(C)C2CCN(Cc3ccccc3)CC2)nc(C)c1N,[Zn],CC(=O)O,,,,test
US05942511,C=CCS.CC(C)CCOc1ccc(Cl)nn1>>C=CCSc1ccc(OCCC(C)C)nn1,,CO,,[Na],,test
US20030181496A1,CCC=O.COC(=O)c1cccc(C=O)c1N>>COC(=O)c1cccc2cc(C)cnc12,,CO,,C1CCNCC1,,test
US20100190826A1,CC(=O)OC(C)=O.CCOC(=O)c1cccc(-n2c(C3CCNCC3)nc3cc(C(F)(F)F)ccc32)c1>>CCOC(=O)c1cccc(-n2c(C3CCN(C(C)=O)CC3)nc3cc(C(F)(F)F)ccc32)c1,,CCOC(C)=O,,C1CCOC1,CCN(CC)CC,test
US20120088748A1,COCC(O)(CCN)c1ccc(Cl)c(Cl)c1.O=C(Cl)CCl>>COCC(O)(CCNC(=O)CCl)c1ccc(Cl)c(Cl)c1,,C1CCOC1,,CCN(CC)CC,,test
US20150080362A1,CN(C)c1ccc(-c2[nH]c(=O)c(C(=O)OCc3ccccc3)c(O)c2CO)cc1>>CN(C)c1ccc(-c2[nH]c(=O)c(C(=O)O)c(O)c2CO)cc1,[Pd],CO,ClCCl,,,test
US20070010537A1,Nc1cccc(S)c1.OC1CCCCc2ccccc21>>Nc1cccc(SC2CCCCc3ccccc32)c1,,C1CCOC1,O,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US05432273,CC(=O)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@@H]1F>>Cc1cn([C@H]2C[C@H](F)[C@@H](CO)O2)c(=O)[nH]c1=O,,CO,,C[O-].[Na+],,test
US20020082218A1,COc1cc(CO)ccc1-c1ccccc1.O=C1CCC(=O)N1Br>>COc1cc(CBr)ccc1-c1ccccc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US05696159,CC(C)=O.COc1cc2c(cc1F)C(=Cc1ccc(SC)cc1)C(C)=C2CC(=O)O>>COc1cc2c(cc1F)C(=Cc1ccc(S(C)=O)cc1)C(C)=C2CC(=O)O,,CO,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20020019383A1,NC1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1.O=S(=O)(Cl)c1cccs1>>O=S(=O)(NC1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1)c1cccs1,,ClCCl,,CCN(CC)CC,,test
US05925638,COC(CCCCN1CCN(C(=O)OC(C)(C)C)CC1)OC>>c1ccc2[nH]ccc2c1,,O=S(=O)(O)O,,O=C([O-])[O-].[K+].[K+],,test
US03975384,CCOc1nc(N2CCNCC2)nc(N2CCS(=O)CC2)c1[N+](=O)[O-].O=C1CCC(=O)O1>>CCOc1nc(N2CCN(C(=O)CCC(=O)O)CC2)nc(N2CCS(=O)CC2)c1[N+](=O)[O-],,C1COCCO1,,,,test
US20060063820A1,C=O.Oc1cc(Cl)cc(Cl)c1>>OCc1c(Cl)cc(O)cc1Cl,,O,,CC(=O)O,[Na+].[OH-],test
US06380392B1,OCc1cccc(CO)n1>>O=Cc1cccc(C=O)n1,,C1COCCO1,,,,test
US20050059650A1,CCC(CC)CO.CS(=O)(=O)c1ccc(-n2ncc3c(OC4CCNCC4)ncnc32)cc1.O=C(n1ccnc1)n1ccnc1>>CCC(CC)COC(=O)N1CCC(Oc2ncnc3c2cnn3-c2ccc(S(C)(=O)=O)cc2)CC1,,CS(C)=O,,CCN(CC)CC,,test
US20030130265A1,COC(=O)c1ccc2c(c1)nc(CCc1ccc(C#N)cc1)n2C>>Cn1c(CCc2ccc(C#N)cc2)nc2cc(C(=O)O)ccc21,,CO,O,Cl,[Na+].[OH-],test
US20080108620A1,C#Cc1cc(Cl)cc(Cl)c1.COc1ccc2cc(C(=O)N(C)OC)cnc2c1>>COc1ccc2cc(C(=O)C#Cc3cc(Cl)cc(Cl)c3)cnc2c1,,C1CCOC1,,[Li]CCCC,,test
US20070105913A1,CCCCc1ccc(C#Cc2ccc(CN(C(=O)CC(C)(C)C)c3ccc4c(c3)C(=O)OC(C)(C)O4)cc2)cc1>>CCCCc1ccc(C#Cc2ccc(CN(C(=O)CC(C)(C)C)c3ccc(O)c(C(=O)O)c3)cc2)cc1,,CCO,,[Na+].[OH-],,test
US20100179148A1,CCOC(=O)Nc1cccc(Cn2nc(-c3ccc(C#N)cc3)ccc2=O)c1>>CCOC(=O)Nc1cccc(Cn2nc(-c3ccc(CN)cc3)ccc2=O)c1,[Ni],N,,,,test
US20110218200A1,BrBr.Nc1cccc([N+](=O)[O-])c1>>Nc1cc([N+](=O)[O-])ccc1Br,,CC(=O)O,,,,test
US05084084,CCOC(=O)/C=C(\N)C(F)(F)F.Cc1nnc(-c2cc(N=C=O)c(F)cc2Cl)o1>>Cc1nnc(-c2cc(-n3c(=O)cc(C(F)(F)F)[nH]c3=O)c(F)cc2Cl)o1,,CN(C)C=O,Cc1ccccc1,[H-].[Na+],,test
US08389727B2,CCOC=C(C(=O)OCC)C(=O)OCC.Nc1cc(C(F)(F)F)ccc1Cl>>CCOC(=O)C(=CNc1cc(C(F)(F)F)ccc1Cl)C(=O)OCC,,CCCCCC,,Cc1ccccc1,,test
US20070049603A1,COc1cccc2cc(N(CCO)c3coc4cnccc34)ccc12>>OCCN(c1ccc2c(O)cccc2c1)c1coc2cnccc12,,ClCCl,,BrB(Br)Br,,test
US20160016908A1,COc1ccc2c(n1)[C@H](NC(=O)OCc1ccccc1)[C@@H](C)[C@H](C1CC1)N2C(C)=O>>COc1ccc2c(n1)[C@H](N)[C@@H](C)[C@H](C1CC1)N2C(C)=O,[Pd],CCOC(C)=O,,,,test
US20020072624A1,C[C@]12C[C@H](c3ccc(OCCCCCS(=O)CCCC(F)(F)C(F)(F)F)cc3)[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2O.Cc1ccc(S(=O)(=O)OC2CCCC2)cc1>>C[C@]12C[C@H](c3ccc(OCCCCCS(=O)CCCC(F)(F)C(F)(F)F)cc3)[C@@H]3c4ccc(OC5CCCC5)cc4CC[C@H]3[C@@H]1CC[C@@H]2O,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US05434292,COC(=O)C(C)c1ccc(C[C@@H]2CCC[C@@H]2O)c(Cl)c1>>CC(C(=O)O)c1ccc(C[C@@H]2CCC[C@@H]2O)c(Cl)c1,,CO,,Cl,[Na+].[OH-],test
US20060111373A1,CC(C)(C)OC(=O)n1ccc2c(Cn3ncc4c(-c5ccco5)nc(N)nc43)cccc21>>Nc1nc(-c2ccco2)c2cnn(Cc3cccc4[nH]ccc34)c2n1,,CO,O,C[O-].[Na+],,test
US20090156615A1,Cc1nc(-n2ccc(N)cc2=O)sc1C(=O)NCc1ccccc1.O=C(Cl)c1ccccc1>>Cc1nc(-n2ccc(NC(=O)c3ccccc3)cc2=O)sc1C(=O)NCc1ccccc1,CN(C)c1ccncc1,c1ccncc1,,O,,test
US05599829,CCI.NC(=O)CNC(=S)Nc1ccccc1>>CCSC1=NCC(=O)N1c1ccccc1,,CCO,,,,test
US20130035326A1,CC1(c2cc(NC(=O)Oc3ccccc3)no2)CC1.Nc1ccc(-c2ccc(NC(c3ccccc3)(c3ccccc3)c3ccccc3)nc2)cn1>>CC1(c2cc(NC(=O)Nc3ccc(-c4ccc(NC(c5ccccc5)(c5ccccc5)c5ccccc5)nc4)cn3)no2)CC1,CN(C)c1ccncc1,CN(C)C=O,,CCN(CC)CC,O,test
US20160115158A1,COc1ccc(Br)nc1N.O=C1CCC(=O)N1Cl>>COc1cc(Cl)c(Br)nc1N,,CC(=O)O,,,,test
US20020183512A1,Clc1c2ccccc2nc2ccccc12.Nc1ccc(CCCCCCCO)cc1>>OCCCCCCCc1ccc(Nc2c3ccccc3nc3ccccc23)cc1,,CO,,CCN(CC)CC,,test
US20160229865A1,C=CC(=O)Cl.CC(C)(C)OC(=O)N1CCC[C@@H](Nc2nc(Cl)nn3cccc23)C1>>C=CC(=O)N1CCC[C@@H](Nc2nc(Cl)nn3cccc23)C1,,ClCCl,O,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20040063974A1,C=CCBr.C[C@@H](O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>C=CCO[C@H](C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,C1CCOC1,,[H-].[Na+],,test
US04510085,CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O.NC1C2CC3CC(C2)CC1C3>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)NC1C2CC3CC(C2)CC1C3,,ClCCl,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US04557753,CC(=O)c1ccc(CBr)cc1.Cn1ncc(C(=O)c2ccc(Cl)cc2Cl)c1O>>CC(=O)c1ccc(COc2c(C(=O)c3ccc(Cl)cc3Cl)cnn2C)cc1,,CCN(CC)CC,,c1ccccc1,,test
US20030171359A1,CC(=O)NCC1CCC(CCC(=O)O)CC1>>NCC1CCC(CCC(=O)O)CC1,,CC(C)=O,,Cl,,test
US20050234096A1,CCOC(=O)COc1ccc(S(=O)(=O)N2CC(C)(C)c3ccc(-c4ccc(F)cc4)cc3C2C)cc1C>>Cc1cc(S(=O)(=O)N2CC(C)(C)c3ccc(-c4ccc(F)cc4)cc3C2C)ccc1OCC(=O)O,,CCO,,[Na+].[OH-],,test
US20090143438A1,Cc1c(OCCCCCO)ccnc1CCl.Sc1nc2ccccc2[nH]1>>Cc1c(OCCCCCO)ccnc1CSc1nc2ccccc2[nH]1,,CCO,,CO,[Na+].[OH-],test
US20100267561A1,Fc1ccc(C(F)(F)F)cc1.Ic1cc[nH]n1>>FC(F)(F)c1ccc(-n2ccc(I)n2)cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05045465,NC(CO)(CO)CO.O=P(O)(O)O>>NC(CO)(CO)CO.O=P(O)(O)O,,O,,,,test
US20100317675A1,C=C(OCC)c1ccc2nc(C(=O)Nc3ccccc3)cn2c1.O=C1CCC(=O)N1Br>>O=C(CBr)c1ccc2nc(C(=O)Nc3ccccc3)cn2c1,,C1CCOC1,ClCCl,O,,test
US04709044,CCCCCC(=O)Cl.Cc1c[nH]c(=O)[nH]1>>CCCCCC(=O)c1[nH]c(=O)[nH]c1C,,O=[N+]([O-])c1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20070208018A1,COC(=O)c1cc(N2CCSCC2)c(C(F)(F)F)cc1N.O=C(Cl)Cl>>COC(=O)c1cc(N2CCSCC2)c(C(F)(F)F)cc1N=C=O,,Cc1ccccc1,,,,test
US20100249123A1,CC(C)(C#N)c1ccc([N+](=O)[O-])cc1Cl>>CC(C)(CN)c1ccc([N+](=O)[O-])cc1Cl,,C1CCOC1,,B,,test
US20080045550A1,CC(C)(C)OC(=O)N1CCC(N)CC1.Clc1ccnc(Cl)n1>>CC(C)(C)OC(=O)N1CCC(Nc2ccnc(Cl)n2)CC1,,CN(C)C=O,,,,test
US20070032525A1,NCC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1.O=C(N=C=S)OCC1c2ccccc2-c2ccccc21>>O=C(NC(=S)NCC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)OCC1c2ccccc2-c2ccccc21,,C1CCOC1,,,,test
US20070072853A1,COC(C)(C)c1nc2cc(N(C)C(C)=O)ccc2n1CC1CCOCC1>>CNc1ccc2c(c1)nc(C(C)(C)OC)n2CC1CCOCC1,,CCO,,,,test
US05880291,COC(=O)C1CCN1[C@@H](C)c1ccccc1.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>COC(=O)C1CCN1[C@@H](C)c1ccccc1.O=C(O)C(O)C(O)C(=O)O,,CO,,,,test
US04477464,O=C1Nc2ccccc2OCC1N1C(=O)c2ccccc2C1=O>>NC1COc2ccccc2NC1=O,,CCO,,NN,O,test
US20080039499A1,CC(C)(C)OC(=O)N1CCC(NC(=O)c2csc(NC(=O)c3ccc(F)cc3)n2)CC1.Cl>>Cl.O=C(Nc1nc(C(=O)NC2CCNCC2)cs1)c1ccc(F)cc1,,C1COCCO1,CO,,,test
US20060041137A1,COC(=O)CC(C)=O.NN.[O-][n+]1cccc2ccccc21>>CC1=NNC(=O)/C1=C1/C=Cc2ccccc2N1,,CC(=O)OC(C)=O,,,,test
US05017573,CNCCNCc1ccccc1.O=[N+]([O-])C(CO)(CO)CO>>CN1CCN(Cc2ccccc2)CC(CO)([N+](=O)[O-])C1,,O,,O=C([O-])O.[Na+],,test
US20100041663A1,COC(=O)c1cnc(N2CC=C(c3nnc(Cc4ccccc4)c(C)c3C)CC2)cn1>>COC(=O)c1cnc(N2CCC(c3nnc(Cc4ccccc4)c(C)c3C)CC2)cn1,[Pd],CCO,,,,test
US20120245144A1,Cn1nccc1C1=CN(C(=O)OC(C)(C)C)CCC1>>Cn1nccc1C1CCCN(C(=O)OC(C)(C)C)C1,[Pd],CO,,,,test
US05912247,CO[C@@H]1C[C@H](Oc2nc(N3CCN(C(=O)OCc4ccccc4)CC3)nc3ccccc23)[C@@H](O)[C@H]1O>>CO[C@@H]1C[C@H](Oc2nc(N3CCNCC3)nc3ccccc23)[C@@H](O)[C@H]1O,[Pd],CO,,,,test
US20130143940A1,CNC(C)=CC(=O)OC.O=C(Cl)c1ccc(F)cc1Cl>>CNC(C)=C(C(=O)OC)C(=O)c1ccc(F)cc1Cl,,Cc1ccccc1,,CCN(CC)CC,,test
US20070167443A1,CON(C)C(=O)c1cn(Cc2cccc(Br)n2)c2ccccc2c1=O.Cc1cnc(I)cc1C>>Cc1cnc(C(=O)c2cn(Cc3cccc(Br)n3)c3ccccc3c2=O)cc1C,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20120157430A1,CNC.O=C(Cl)c1cnnc(Cl)c1>>CN(C)C(=O)c1cnnc(Cl)c1,,C1CCOC1,ClCCl,,,test
US20160158207A1,Cc1c(-c2ccc3c(c2)CCN3C(=O)OC(C)(C)C)cnn1C>>Cc1c(-c2ccc3c(c2)CCN3)cnn1C,,CCOC(C)=O,,Cl,,test
US06028195,BrCC1CC1.COc1ccccc1N1CCN(C(=O)Nc2cc(C)c(C)nc2OC)CC1>>COc1ccccc1N1CCN(C(=O)N(CC2CC2)c2cc(C)c(C)nc2OC)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20090247519A1,COCC(=O)c1ccccc1.Nc1ccccc1C(F)(F)F>>COc1ccccc1/C(C)=N/c1ccccc1C(F)(F)F,,CCCCCC,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US20140350019A1,CCOC(=O)CBr.Cc1cc(-c2cccc(F)c2)cc(CNc2c(F)ccc(O)c2F)c1F>>CCOC(=O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)cc(C)c2F)c1F,,CCC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040138255A1,Cn1c(C(=O)O)cc2cc(NS(=O)(=O)C(F)(F)F)ccc21.Nc1ccccc1>>Cn1c(C(=O)Nc2ccccc2)cc2cc(NS(=O)(=O)C(F)(F)F)ccc21,,CN(C)C=O,ClCCl,ClCCCl,On1nnc2ccccc21,test
US20140094465A1,O=c1c(Oc2ccc([N+](=O)[O-])c(F)c2)c(C(F)(F)F)oc2cc(O)ccc12.OCc1ccccc1>>O=c1c(Oc2ccc([N+](=O)[O-])c(OCc3ccccc3)c2)c(C(F)(F)F)oc2cc(O)ccc12,,CS(C)=O,,[H-].[Na+],[Cl-].[NH4+],test
US20100292210A1,Cc1cc(C(O)CN)n(C)n1.O=Cc1ccc(Cl)nc1Cl>>Cc1cc(C(O)CNCc2ccc(Cl)nc2Cl)n(C)n1,,CO,ClCCl,CC(=O)O,[BH3-]C#N.[Na+],test
US20100261698A1,CC(C)(C)OC(=O)n1c(-c2cncc(OS(=O)(=O)N3CCCC3)c2)cc2ccc(Cl)cc21>>O=S(=O)(Oc1cncc(-c2cc3ccc(Cl)cc3[nH]2)c1)N1CCCC1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20140243302A1,Cc1c(C(N)=O)cnc2ccc(OCc3ccccc3)nc12>>Cc1c(C#N)cnc2ccc(OCc3ccccc3)nc12,,ClCCl,,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US20090156642A1,O=Cc1c[nH]c(-c2ccccc2F)n1.O=S(=O)(Cl)c1ccoc1>>O=Cc1cn(S(=O)(=O)c2ccoc2)c(-c2ccccc2F)n1,,C1CCOC1,O,C1COCCOCCOCCOCCO1,[H-].[Na+],test
US20070208005A1,CNC(=O)c1cnc(OCc2ccc3c(c2)CCN(C(=O)OC(C)(C)C)CC3)cn1>>CNC(=O)c1cnc(OCc2ccc3c(c2)CCNCC3)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05409930,COC(=O)NC=Cc1cccnc1.COc1cc(N)c(C=O)cc1OC>>COc1cc2cc(-c3cccnc3)cnc2cc1OC,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20120270877A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N1CCC(N)C1>>CC(=O)NC1CCN(C(=O)OC(C)(C)C)C1,,CC(Cl)Cl,,CCN(CC)CC,,test
US04413010,COc1ccc(Oc2cccc(C)c2)cc1>>Cc1cccc(Oc2ccc(O)cc2)c1,,CC(=O)O,,Br,,test
US04661617,CCOC(=O)C=C(C)CBr.COc1cc(C=O)ccc1O>>CCOC(=O)C=C(C)COc1ccc(C=O)cc1OC,,CCOCC,CN(C)C=O,[Na+].[OH-],,test
US20110065724A1,COC(=O)c1c(NC(=O)c2cc(Cl)ccc2OC)csc1-c1ccc(C)c(F)c1F>>COC(=O)c1c(NC(=O)c2cc(Cl)ccc2O)csc1-c1ccc(C)c(F)c1F,,ClCCl,,BrB(Br)Br,,test
US20030195221A1,CC(C)(Nc1nc(Cl)c(-c2ccc(F)cc2)c(-c2ccncc2)n1)c1ccccc1.NN>>CC(C)(Nc1nc(NN)c(-c2ccc(F)cc2)c(-c2ccncc2)n1)c1ccccc1,,CC(C)O,,O,,test
US20160214935A1,CCOC(=O)c1cccc(Sc2c[nH]c3c(F)c(Cl)ccc23)c1F.O=S(=O)(Cl)Cl>>CCOC(=O)c1cccc(Sc2c(Cl)[nH]c3c(F)c(Cl)ccc23)c1F,,CCOCC,,,,test
US20070155721A1,CCOC(=O)C1=C2COCC(=O)N2CC1>>CCOC(=O)C1CCN2C(=O)COCC12,O=[Pt]=O,CC(=O)O,ClCCl,,,test
US20160200725A1,CNc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)c(=O)n(CC[N+](C)([O-])C3CN(C(=O)OC(C)(C)C)C3)c2n1>>CNc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)c(=O)n(CCN(C)C3CN(C(=O)OC(C)(C)C)C3)c2n1,[Zn],CO,,[Cl-].[NH4+],,test
US20040138208A1,CC(C)(C)OC(=O)ONCCc1ccc(O)cc1.CN(C)C(=O)Cl>>CN(C)C(=O)Oc1ccc(CCNOC(=O)OC(C)(C)C)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US05245037,C[C@@H]1CNC[C@H]1NC(=O)OC(C)(C)C.O=C(Cl)c1ccccc1>>C[C@@H]1CN(C(=O)c2ccccc2)C[C@H]1NC(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20060173019A1,COCN(c1cc(C)cnc1C(=O)c1c(C)ccnc1C)S(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1>>Cc1cnc(C(=O)c2c(C)ccnc2C)c(NS(=O)(=O)c2ccc(Cl)c(C(F)(F)F)c2)c1,,C1COCCO1,Cl,O,,test
US20110118251A1,CCOC(=O)c1nn(-c2ncccc2Cl)cc1CN1CCC2(CC1)OCC(F)(F)c1cc(Cl)sc12>>OCc1nn(-c2ncccc2Cl)cc1CN1CCC2(CC1)OCC(F)(F)c1cc(Cl)sc12,,C1CCOC1,CCO,[BH4-].[Li+],,test
US20110237565A1,BrBr.O=[N+]([O-])c1c(O)ccnc1O>>O=[N+]([O-])c1c(O)ncc(Br)c1O,,CC(=O)O,,,,test
US20100160308A1,CN1CCNCC1.NC(=O)c1sc(Nc2cc(C=O)ccc2[N+](=O)[O-])nc1-c1ccccc1Cl>>CN1CCN(Cc2ccc([N+](=O)[O-])c(Nc3nc(-c4ccccc4Cl)c(C(N)=O)s3)c2)CC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20120065204A1,COC(=O)c1ccc2c(c1)CC(N)CC2.NO.O=S(=O)(Cl)c1cccnc1>>O=C(NO)c1ccc2c(c1)CC(NS(=O)(=O)c1cccnc1)CC2,,ClCCl,,[K+].[OH-],,test
US20100152165A1,CCOC(=O)/C=C/c1ccc(C(=O)OC)cc1[N+](=O)[O-]>>COC(=O)c1ccc2c(c1)NC(=O)CC2,[Pd],C1CCOC1,,CO,[H][H],test
US20140163026A1,COC(=O)Cc1ccc(C#N)cc1C.NO>>COC(=O)Cc1ccc(C(=N)NO)cc1C,,CCO,,Cl,O=C([O-])O.[Na+],test
US20070208005A1,CC(C)(C)OC(=O)N1CCc2ccc(COS(C)(=O)=O)cc2CC1.COC(=O)c1ccc(O)nc1>>COC(=O)c1ccc(OCc2ccc3c(c2)CCN(C(=O)OC(C)(C)C)CC3)nc1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US04650811,CC(C)(C)N.ClCCOc1ccccc1C=Cc1cccc2[nH]ccc12>>CC(C)(C)NCCOc1ccccc1C=Cc1cccc2[nH]ccc12,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100035883A1,CCOC(=O)c1cc(F)cc2c1C(=O)C(c1ccccc1)C(c1nccn1C)N2.NN>>Cn1ccnc1C1Nc2cc(F)cc3c(=O)[nH]nc(c23)C1c1ccccc1,,CO,,O,,test
US20090291917A1,CCI.N#Cc1ccc(Oc2ccc3c(c2)COB3O)cc1O>>CCOc1cc(Oc2ccc3c(c2)COB3O)ccc1C#N,,O,,CN(C)C=O,[H-].[Na+],test
US20020049204A1,CC1(C)OC(=O)Nc2ccc(B(O)O)cc21.N#Cc1cc(Br)cs1>>CC1(C)OC(=O)Nc2ccc(-c3csc(C#N)c3)cc21,,O,,,,test
US20040122057A1,CCOC(=O)C(OCC)c1c(F)cc(O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)cc1F>>CCOC(=O)C(OCC)c1c(F)cc(O)cc1F,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20140161740A1,C=C(C)C(=C)C.C=CC(=O)OC>>COC(=O)C1CCC(C)=C(C)C1,,Cc1ccccc1,,,,test
US20110263561A1,Clc1ccccc1CCC1CCCN1c1ncnc2[nH]cnc12>>Clc1ccccc1CC[C@@H]1CCCN1c1ncnc2[nH]cnc12,,CO,,CCNCC,,test
US20150023913A1,CC1(C(=O)OCc2ccccc2)OCCCC1=O>>CC1(C(=O)OCc2ccccc2)OCCCC1O,,CO,,[BH4-].[Na+],,test
US05124069,CCCCCCCCOc1ccc(C(=O)O)cc1C#N.CCCCCC[C@@H]1CC[C@H](O)C(=O)O1>>CCCCCCCCOc1ccc(C(=O)O[C@@H]2CC[C@@H](CCCCCC)OC2=O)cc1C#N,,c1ccccc1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04851422,O=C([O-])CCC(=O)C(=O)OCc1ccc([N+](=O)[O-])cc1.O=S(Cl)Cl>>O=C1CCC(Cl)(C(=O)OCc2ccc([N+](=O)[O-])cc2)O1,,ClCCCl,,,,test
US05559230,CC(=O)OC(C)=O.NC1Cc2ccccc2N(C(=O)c2ccc(NC(=O)c3cc(Cl)cc(Cl)c3)cc2)C1>>CC(=O)NC1Cc2ccccc2N(C(=O)c2ccc(NC(=O)c3cc(Cl)cc(Cl)c3)cc2)C1,,ClCCl,,,,test
US06218397B1,CSc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(C)nc(Cl)c12.Cc1ccc(CNCCCO)cc1>>CSc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(C)nc(N(CCCO)Cc3ccc(C)cc3)c12,,CC#N,,,,test
US20020032189A1,CN(C)CC1CCc2cc(O)ccc2C1.ClCc1nnc(-c2ccccc2)o1>>CN(C)CC1CCc2cc(OCc3nnc(-c4ccccc4)o3)ccc2C1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20030055071A1,CN.Cn1cnc(S(=O)(=O)Cl)c1>>CNS(=O)(=O)c1cn(C)cn1,,C1CCOC1,ClCCl,O,,test
US20080114024A1,CC(C)NC(C)C.COc1ccc(C#N)cc1.Cc1nc(C(F)(F)F)ccc1C(=O)O.[Li]CCCC>>CC(C)[N-]C(C)C.COc1ccc(-c2cc3nc(C(F)(F)F)ccc3c(O)n2)cc1.[Li+],,C1CCOC1,,,,test
US04587261,COC(=O)NN.O=C1CCCCC1Cc1ccccc1>>COC(=O)NN=C1CCCCC1Cc1ccccc1,,CCO,,,,test
US20160199372A1,CC(C)c1nc(-c2cccc([N+](=O)[O-])c2)no1>>CC(C)c1nc(-c2cccc(N)c2)no1,[Zn],CCO,,[Cl-].[NH4+],,test
US20060293319A1,CC(=O)c1ccc(N=C=O)cc1.O=C1Nc2cc(Cl)ccc2C1(Cc1cccc(Cl)c1)C1CCCNC1>>CC(=O)c1ccc(NC(=O)N2CCCC(C3(Cc4cccc(Cl)c4)C(=O)Nc4cc(Cl)ccc43)C2)cc1,,ClCCl,,CCN(CC)CC,,test
US05011932,CC(=O)c1ccc(Cl)nc1.NNC(=O)C1CC1>>CC(=NNC(=O)C1CC1)c1ccc(Cl)nc1,,CCO,,,,test
US04797399,C=O.CC#N.NN1CCN(C(=O)Cn2c(=O)sc3ccc(Cl)cc32)CC1>>CN(C)N1CCN(C(=O)Cn2c(=O)sc3ccc(Cl)cc32)CC1,,CC#N,,CC(=O)O,[BH3-]C#N.[Na+],test
US07244763B2,COC(=O)Cn1ccc2cc(SC(=O)N(C)C)ccc21>>COC(=O)Cn1ccc2cc(S)ccc21,,CO,,,,test
US20110124626A1,CC(C)(C)OC(=O)N1CCc2ccc(C(=O)OCC3CCN(Cc4ccccc4)CC3)cc2CC1.Cl>>Cl.O=C(OCC1CCN(Cc2ccccc2)CC1)c1ccc2c(c1)CCNCC2,,CCOCC,,CO,,test
US20060148862A1,CCCCCCCNC(=O)N(C)c1ncc(-c2ccc(C[C@H](OCC)C(=O)OC)cc2)s1>>CCCCCCCNC(=O)N(C)c1ncc(-c2ccc(C[C@H](OCC)C(=O)O)cc2)s1,,C1CCOC1,O,[Li+].[OH-],,test
US05439925,CCOC(=O)C(=O)c1ccc2c(c1)C(C)(C)CCC2(C)C>>CC1(C)CCC(C)(C)c2cc(C(=O)C(=O)O)ccc21,,O,,CCO,[Na+].[OH-],test
US20120190852A1,CC(C)(C)OC(=O)CN(C(=O)OC(C)(C)C)c1cccc(C(Cc2ccc(-c3ccccc3)cc2)NS(=O)(=O)c2cccnc2)n1.Cl>>Cl.O=C(O)CNc1cccc(C(Cc2ccc(-c3ccccc3)cc2)NS(=O)(=O)c2cccnc2)n1,,ClCCl,,C1COCCO1,,test
US04057543,CC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@]4(C)C(=O)CC[C@H]4[C@@H]3CC[C@@H]2C1>>C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@]34C)[C@@H]1CCC2=O,,CO,,O,[Na+].[OH-],test
US20070010694A1,CN=C1CCC(c2ccc(Cl)c(Cl)c2)c2ccccc21.Clc1ccccc1Cl>>CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc21.Cl,[Ni],Clc1ccccc1Cl,,CO,[H][H],test
US04665174,C=CCC1C(=O)C=CC1(C)O.OCCS>>C=CCC1=C(C)C(SCCO)CC1=O,,C1CCOC1,,[H-].[Na+],,test
US20050101592A1,CC(F)(F)CNCCO.CCOC(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1O>>CC(F)(F)CN(CCO)C(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1O,,CCOC(C)=O,,,,test
US20120165322A1,COC(=O)c1ccc2c(=O)[nH]ccc2n1>>O=C(O)c1ccc2c(=O)[nH]ccc2n1,,C1CCOC1,CO,,,test
US20060089398A1,CCN(CC)c1ccccc1N.Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)O>>CCN(CC)c1ccc(NC(=O)c2c(-c3c(Cl)cccc3Cl)noc2C)cc1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20130109682A1,C[C@H]1O[C@@H](c2ccncc2N)C[C@@H](O)[C@]1(C)O.O=C(O)c1nn(Cc2ccccc2)cc1[N+](=O)[O-]>>C[C@H]1O[C@@H](c2ccncc2NC(=O)c2nn(Cc3ccccc3)cc2[N+](=O)[O-])C[C@@H](O)[C@]1(C)O,,CN(C)C=O,,ClCCCl,On1nnc2cccnc21,test
US06034275,CC(O)(c1ccc(O)cc1)c1ccc(Br)cc1>>C=C(c1ccc(O)cc1)c1ccc(Br)cc1,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20060257987A1,CCOC(=O)CCc1ccc(OCCC(C)Oc2ccc(CC)cc2-c2ccccn2)cc1CC>>CCc1ccc(OC(C)CCOc2ccc(CCC(=O)O)c(CC)c2)c(-c2ccccn2)c1,,CCO,,Cl,[Na+].[OH-],test
US20050043388A1,NNC(=O)c1cccc(O)c1.O=C1Nc2ccc(I)cc2C1=O>>O=C1Nc2ccc(I)cc2C1=NNC(=O)c1cccc(O)c1,,CC(=O)O,,,,test
US05616765,C[Si](C)(C)Cl.Oc1cccc2c1CC2>>C[Si](C)(C)Oc1cccc2c1CC2,,c1ccccc1,,CCN(CC)CC,,test
US20090291971A1,Brc1cnc(On2nnc3cccnc32)nc1.COCCOC.O=C(O)Cc1ccc(B(O)O)cc1>>COC(=O)c1ccc(Oc2ncc(Br)cn2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04398026,C1CCNC1.C=C1CC(=O)O1.CC(C)(S)[C@@H](N)C(=O)O>>CC1(CC(=O)N2CCCC2)NC(C(=O)O)C(C)(C)S1,,c1ccccc1,,,,test
US20150175557A1,CC(C)(C)OC(=O)NC1CC2(CC(=O)C2)C1.[Li]C>>CC1(O)CC2(CC(NC(=O)OC(C)(C)C)C2)C1,,C1CCOC1,,,,test
US20120142665A1,C1CNC1.CCOC(=O)c1c(C(=O)O)cnn1C>>CCOC(=O)c1c(C(=O)N2CCC2)cnn1C,,CCOC(C)=O,,CCN(C(C)C)C(C)C,,test
US20090270642A1,C/C=C1/CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)C3=CC[C@]12C.CC(=O)OC(C)=O>>C/C=C1/CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](OC(C)=O)CC[C@]4(C)C3=CC[C@]12C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20060166964A1,CN(C)S(=O)(=O)NC(=O)c1ccc2c(C3CCCCC3)c(Br)[nH]c2c1.COc1ccc(B(O)O)c(C=O)c1>>COc1ccc2c(c1)C(O)n1c-2c(C2CCCCC2)c2ccc(C(=O)NS(=O)(=O)N(C)C)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US20160272655A1,Cc1nn2c3c(nc2s1)CCN(C(=O)OC(C)(C)C)C3c1cc(C(N)=O)cs1>>Cc1nn2c3c(nc2s1)CCN(C(=O)OC(C)(C)C)C3c1cc(C#N)cs1,,O=C([O-])O,[Na+],CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US20040048915A1,CCI.Oc1ccc2cc[nH]c2c1>>CCOc1ccc2cc[nH]c2c1,,CN(C)C=O,,[H-].[Na+],,test
US20100160280A1,CC(C)(C)OC(=O)N1CC=C(c2nccnc2Oc2ccc(Nc3ccccn3)cc2)CC1.Cl.ClCCl>>Cl.Cl.c1ccc(Nc2ccc(Oc3nccnc3C3CCNCC3)cc2)nc1,,C1COCCO1,,,,test
US20110288065A1,CC(C)[Si](c1ncc(-c2cc(Nc3cnccn3)nc(N[C@@H](C)c3ccc(F)cc3)n2)o1)(C(C)C)C(C)C>>C[C@H](Nc1nc(Nc2cnccn2)cc(-c2cnco2)n1)c1ccc(F)cc1,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20030139473A1,CCOC(=O)Cc1ccc(OC/C=C(\C)c2ccc3c(c2)Cc2ccccc2-3)cc1>>C/C(=C\COc1ccc(CC(=O)O)cc1)c1ccc2c(c1)Cc1ccccc1-2,,[Na+],[OH-],CO,,test
US05168103,CC(C)(C)OC(=O)NCCCNCC#N.CCOc1c(OCC)c(=O)c1=O>>CCOc1c(N(CC#N)CCCNC(=O)OC(C)(C)C)c(=O)c1=O,,CCO,,,,test
US20100227872A1,Cc1nocc1C(=O)O.Nc1cnc(-c2cc(Cl)ccc2OC(F)(F)F)c(N)n1>>Cc1nocc1C(=O)Nc1cnc(-c2cc(Cl)ccc2OC(F)(F)F)c(N)n1,CN(C)C=O,CC#N,ClCCl,Cc1cccc(C)n1,O=C(Cl)C(=O)Cl,test
US06410737B1,NNc1ccc(C(F)(F)F)cc1>>Nc1ccc(C(F)(F)F)cc1,[Ni],CO,,,,test
US20110178083A1,CC(C)(C)c1ccc(C2CC2C(=O)N/N=C/c2cccc3cnccc23)cc1.CI>>CN(/N=C/c1cccc2cnccc12)C(=O)C1CC1c1ccc(C(C)(C)C)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20120083469A1,CC[C@@](CCCCB1OC(C)(C)C(C)(C)O1)(NC(=O)OC(C)(C)C)C(=O)OC.Cl>>CC[C@](N)(CCCCB(O)O)C(=O)O.Cl,,O,,,,test
US20110201635A1,CC(C)(C)CC1CN(C(=O)Cl)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12.CC1(C)OC[C@H](CCN)O1>>CC(C)(C)CC1CN(C(=O)NCC[C@H](O)CO)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12,,C1CCOC1,,CCN(CC)CC,Cl,test
US20080004442A1,COC(=O)c1cc(-c2ccc(C)cc2)cc(-n2nnnc2C)c1>>Cc1ccc(-c2cc(C(=O)O)cc(-n3nnnc3C)c2)cc1,,C1CCOC1,O,[Li]O,,test
US20030013720A1,O=CC1CC1.O=S(=O)(NCC1(c2ccc(I)cc2)CCNCC1)c1ccc(F)c(Cl)c1>>O=S(=O)(NCC1(c2ccc(I)cc2)CCN(CC2CC2)CC1)c1ccc(F)c(Cl)c1,,CCOC(C)=O,ClCCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090176778A1,NCc1ccc(N2CCOCC2)cc1.O=C(O)c1nc2c(C(F)(F)F)cc(-c3ccco3)cn2c1Cl>>O=C(NCc1ccc(N2CCOCC2)cc1)c1nc2c(C(F)(F)F)cc(-c3ccco3)cn2c1Cl,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04517196,CCOC(=O)C(=O)NC1N=C2C(=Cc3ccccc32)S1>>O=C(O)C(=O)NC1N=C2C(=Cc3ccccc32)S1,,O,,O=C([O-])O.[Na+],,test
US04916137,CI.O=c1[nH]c(=S)n2c3c1cnn3C(c1cccc(C(F)(F)F)c1)=CC2>>CSc1nc(=O)c2cnn3c2n1CC=C3c1cccc(C(F)(F)F)c1,,C1CCOC1,,[H-].[Na+],,test
US20090286790A1,CS(=O)(=O)c1cc(CO)cc(C(F)(F)F)c1.O=C1CCC(=O)N1Br>>CS(=O)(=O)c1cc(CBr)cc(C(F)(F)F)c1,,ClCCl,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060229286A1,CCOC(=O)c1cnc2cc(COC)nn2c1>>CCOC(=O)c1cnc2cc(CO)nn2c1,,ClCCl,,BrB(Br)Br,O,test
US20130225561A1,COc1cc(C#N)ccc1CC(O)CO>>COc1cc(C#N)ccc1CC=O,,CO,O,,,test
US04092304,CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1>>CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)O,,CO,,[Na+].[OH-],,test
US20050131017A1,CC(C)c1cccc(CN2CCN([C@H](C(=O)OC(C)(C)C)C(C)(C)C)C2=O)n1.O=C(O)C(F)(F)F>>CC(C)c1cccc(CN2CCN([C@H](C(=O)O)C(C)(C)C)C2=O)n1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20090270350A1,COc1ccc(Cn2c(C)cc(O)cc2=O)cc1.O=C1c2ccccc2C(=O)N1Cc1ccccc1CCl>>COc1ccc(Cn2c(C)cc(OCc3ccccc3CN3C(=O)c4ccccc4C3=O)cc2=O)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120214766A1,CC(C)[C@H](N)CO.N#Cc1ccnc(-n2nc(C(=O)O)c3c2[C@@H]2C[C@@H]2C3)c1>>CC(C)[C@@H](CO)NC(=O)c1nn(-c2cc(C#N)ccn2)c2c1C[C@H]1C[C@@H]21,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US03960894,COC1c2sccc2C(=O)c2ccccc2C1Br>>COc1cc2ccccc2c(=O)c2ccsc12,,CO,,[K+].[OH-],,test
US20080103173A1,CC(C)[C@@H](CO)N=Cc1ccccc1.C[Si](C)(C)Cl>>CC(C)[C@@H](CO[Si](C)(C)C)/N=C/c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20090203667A1,COC(=O)c1c(N)cccc1[N+](=O)[O-]>>Nc1cccc([N+](=O)[O-])c1CO,,C1CCOC1,,[BH4-].[Li+],,test
US20160009701A1,Cc1noc(C)c1-c1cc(C(N)=O)c2[nH]c3cc(NS(=O)(=O)CCCCl)ccc3c2c1>>Cc1noc(C)c1-c1cc(C(N)=O)c2[nH]c3cc(N4CCCS4(=O)=O)ccc3c2c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090233952A1,CCCCCc1ccco1.O=C(OO)c1cccc(Cl)c1>>CCCCCC(=O)/C=C/C=O,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US04742052,COc1ccc(COC(=O)C(C)(C)CCC(=O)OCc2ccc([N+](=O)[O-])cc2)cc1>>COc1ccc(COC(=O)C(C)(C)CCC(=O)O)cc1,,C1CCOC1,O,O=S([O-])[O-].[Na+].[Na+],,test
US20050176775A1,Cc1cc(O)cc(=O)[nH]1.Fc1ccc(CCl)c(F)c1>>Cc1cc(OCc2ccc(F)cc2F)cc(=O)[nH]1,,CN1CCCC1=O,,C1CCC2=NCCCN2CC1,,test
US20100015141A1,CC(C)C#N.COC(=O)c1ccc([N+](=O)[O-])cc1C>>O=C1NCc2cc([N+](=O)[O-])ccc21,,ClC(Cl)(Cl)Cl,,O=C1CCC(=O)N1Br,,test
US20050004114A1,BrCc1ccccc1.O=[N+]([O-])c1cc(Br)cnc1O>>O=c1c([N+](=O)[O-])cc(Br)cn1Cc1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US06967198B2,CC(C)(C)OC(=O)N1CCC(C=CC(=O)Nc2cc3c4c(c[nH]c4c2)C=NNC3=O)CC1.CC(C)(C)OC(=O)N1CCC(C=CC(=O)O)CC1>>CC(=O)O.O=C(C=CC1CCNCC1)Nc1cc2c3c(c[nH]c3c1)C=NNC2=O,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06326369B1,COc1c2c(c(OC)c(OC)c1OC)CCC(CCI)CC2.Oc1ccc(Cl)cc1>>COc1c2c(c(OC)c(OC)c1OC)CCC(CCOc1ccc(Cl)cc1)CC2,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20090318408A1,CN(C)CCCN.COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)N([C@@H]1C[C@H]1c1ccccc1)CC(F)(F)C(=O)N2C>>COc1cc(C(=O)NCCCN(C)C)ccc1Nc1ncc2c(n1)N([C@@H]1C[C@H]1c1ccccc1)CC(F)(F)C(=O)N2C,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20160046583A1,CS(=O)(=O)c1cccc(CN)c1.O=C(O)c1ccc2cncc(-c3ccc(Cl)cc3)c2c1>>CS(=O)(=O)c1cccc(CNC(=O)c2ccc3cncc(-c4ccc(Cl)cc4)c3c2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20100029737A1,COC(=O)c1cc2c([nH]1)CCC2c1cccc(Br)c1>>O=C(O)c1cc2c([nH]1)CCC2c1cccc(Br)c1,,CO,,C1CCOC1,[Li+].[OH-],test
US04940710,O=C(O)c1cn(-c2ccc(F)cc2)c2cc(Cl)c(F)cc2c1=O.c1ccc(OCC2CNCCN2)cc1>>O=C(O)c1cn(-c2ccc(F)cc2)c2cc(N3CCNC(COc4ccccc4)C3)c(F)cc2c1=O,,c1ccncc1,,,,test
US20090286840A1,COC(=O)c1sc(C(=O)CC#N)cc1OC(C)c1ccccc1Cl.NN>>COC(=O)c1sc(-c2cc(N)n[nH]2)cc1OC(C)c1ccccc1Cl,,CCO,,O,,test
US20120065202A1,C[C@H]1COCCN1c1nc(-c2ccc(NC(=O)NC3CC3)cc2)nc2c1CCNC2.O=C(Cl)C1CC1>>C[C@H]1COCCN1c1nc(-c2ccc(NC(=O)NC3CC3)cc2)nc2c1CCN(C(=O)C1CC1)C2,,ClCCl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20110263494A1,CCOC(=O)c1cccc(I)c1.C[C@]12Cn3cnc(-c4ccc(F)cc4)c3C=C1CCC[C@@H]2C=O>>CCOC(=O)c1cccc(C(O)[C@H]2CCCC3=Cc4c(-c5ccc(F)cc5)ncn4C[C@@]32C)c1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20120077799A1,Nc1ncccc1Br.OB(O)c1ccc(OC2CCCCC2)cc1>>Nc1ncccc1-c1ccc(OC2CCCCC2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US05204248,COC(=O)OC.COc1ccc(C(C)=O)cc1>>COC(=O)CC(=O)c1ccc(OC)cc1,,Cc1ccccc1,,[Na],,test
US20110212968A1,COc1ccc(CCNC(=O)C(F)(F)F)cc1OC>>COc1ccc(CCNCC(F)(F)F)cc1OC,,C1CCOC1,O,,,test
US20160159815A1,CC(C)(C)OC(=O)N1CC[C@]2(c3ccccc3)OCO[C@@H]2C1>>c1ccc([C@]23CCNC[C@H]2OCO3)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100272678A1,CC(C)(C)c1cc(N)c(C#N)[se]1.[OH-]>>CC(C)(C)c1cc(N)c(C(N)=O)[se]1,,[Na+],[OH-],CCO,,test
US05057528,O=C(OCc1ccccc1)N1CCC(COc2ccc([N+](=O)[O-])cc2)CC1>>Nc1ccc(OCC2CCN(C(=O)OCc3ccccc3)CC2)cc1,[Zn],CCO,Cl,,,test
US20140093505A1,COC(=O)c1cnc2ccc(Cl)nc2c1Nc1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)c(C(F)(F)F)c1>>CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3c(CO)cnc4ccc(Cl)nc34)cc2C(F)(F)F)CC1,,CCO,,[BH4-].[Na+],,test
US20110207783A1,CCOC(=O)C(CNC(=O)OC(C)(C)C)Cc1cccnc1>>CC(C)(C)OC(=O)NCC(Cc1cccnc1)C(=O)O,,CO,,C1CCOC1,[Li+].[OH-],test
US20120065214A1,COC(=O)c1cc(F)c(C)c(-n2ccnc(NC(C)(C)c3ccccc3OCCCl)c2=O)c1>>Cc1c(F)cc(C(=O)O)cc1-n1ccnc(NC(C)(C)c2ccccc2OCCCl)c1=O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US04663453,CN1CCN(C(=O)Nc2ccccc2N2CCc3cc(Br)ccc32)CC1>>CN1CCN(C2=Nc3ccccc3N3CCc4cc(Br)cc2c43)CC1,,O=P(Cl)(Cl)Cl,,,,test
US20030069428A1,COCC(=O)Nc1cccc2c1C(=O)N(C1CC(OC(C)=O)C(=O)NC1=O)C2=O>>COCC(=O)Nc1cccc2c1C(=O)N(C1CC(O)C(=O)NC1=O)C2=O,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20150259464A1,CCCCCCC(O)CCCCCCCCCCC(=O)O.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CCCCCCC(CCCCCCCCCCC(=O)O)OC(=O)c1ccc([N+](=O)[O-])cc1,,CC(C)=O,,CCN(CC)CC,,test
US20060004043A1,CCOC(=N)c1ccc2[nH]nc(-c3ccc4cc(OCc5ccccn5)ccc4c3)c2c1.NNC(=O)CN1CCCC1>>c1ccc(COc2ccc3cc(-c4n[nH]c5ccc(-c6n[nH]c(CN7CCCC7)n6)cc45)ccc3c2)nc1,,CCO,,CCN(CC)CC,Cl,test
US20070299072A1,C1CCNCC1.COc1ccc(CCNC(=O)C2(C(=O)OCC3c4ccccc4-c4ccccc43)CCN(C(=O)OC(C)(C)C)CC2)cc1>>COc1ccc(CCNC(=O)C2(N)CCN(C(=O)OC(C)(C)C)CC2)cc1,,CN(C)C=O,,,,test
US20120302544A1,FCCBr.O=C1N=C(N2CCCNCC2)SC1=Cc1ccc2c(cnn2Cc2ccc(Cl)cc2C(F)(F)F)c1>>O=C1N=C(N2CCCN(CCF)CC2)SC1=Cc1ccc2c(cnn2Cc2ccc(Cl)cc2C(F)(F)F)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US04665202,O=C(O)CS.O=CC1=C(Cl)c2ccccc2OC1c1ccccc1>>O=CC1=C(SCC(=O)O)c2ccccc2OC1c1ccccc1,,CCO,,O=C([O-])O.[Na+],,test
US20120046170A1,CC(=O)c1cc(Cl)cc(Cl)c1O.Cc1cccc(C(=O)NN)c1>>CC(=NNC(=O)c1cccc(C)c1)c1cc(Cl)cc(Cl)c1O,,CCO,,CC(=O)O,,test
US20070232607A1,CO.Cc1ccc(Oc2ccc(Nc3ncnc4cccc(F)c34)cc2C)cn1>>COc1cccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c12,,CO,,C[O-].[Na+],,test
US20100056563A1,COC(=O)c1cc(I)cnc1Cl.NCc1ccc(C(F)(F)F)cc1>>COC(=O)c1cc(I)cnc1NCc1ccc(C(F)(F)F)cc1,,CCO,CCOC(C)=O,,,test
US06303613B1,CCOC(=O)N1CCC2(CC1)NC(=O)c1cccnc1N2.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCOC(=O)N1CCC2(CC1)NC(=S)c1cccnc1N2,,C1COCCO1,,,,test
US20020068748A1,CCOC(=O)C1CCC(C(=O)[O-])N1Cc1ccccc1>>OCC1CCC(CO)N1Cc1ccccc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140088048A1,O=S(=O)(Cl)c1ccc(C(F)(F)F)cc1.OC1CCC2(CC1)OCCO2>>O=S(=O)(OC1CCC2(CC1)OCCO2)c1ccc(C(F)(F)F)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US06130217,CNc1c(O)cccc1[N+](=O)[O-].CO>>Cn1cnc2cccc(O)c21,[Pd],CO,,CC(=O)O,,test
US20050032786A1,CCN=C=O.NCCc1cccc(-c2nc(=O)c3ccccc3s2)n1>>CCNC(=O)NCCc1cccc(-c2nc(=O)c3ccccc3s2)n1,,CC#N,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20160237069A1,CN(C)CCCN.Cc1cc(Cl)nc(NC(=N)Nc2ccc(Cl)c(Cl)c2)n1>>Cc1cc(NCCCN(C)C)nc(NC(=N)Nc2ccc(Cl)c(Cl)c2)n1,,CC(=O)N(C)C,CCOC(C)=O,,,test
US20030119807A1,CCOC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1.CNCCCN(C)C>>CN(C)CCCN(C)C(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)OC(C)(C)C)n1,,CCO,,,,test
US20060035939A1,CN(c1cc(C(=O)Nc2ccc(C(C)(C)C)cc2)ccc1O)c1ncccc1Cl.COC(=O)CBr>>COC(=O)COc1ccc(C(=O)Nc2ccc(C(C)(C)C)cc2)cc1N(C)c1ncccc1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05021581,N#Cc1ccccc1CBr.Oc1cccc(Cl)c1>>N#Cc1ccccc1COc1cccc(Cl)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20080227774A1,CC(C)CCOS(=O)(=O)C(F)(F)F.COC(=O)c1cccn1CC(=O)OC(C)(C)C>>COC(=O)c1cccn1C(CCC(C)C)C(=O)OC(C)(C)C,,C1CCOC1,Cc1ccccc1,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20050009841A1,CCOC(=O)C1CCN(Cc2ccccc2)CC1=O>>CCOC(=O)C1CCN(Cc2ccccc2)CC1O,,CCOCC,,[Li],,test
US20080214448A1,COC(=O)CCCc1cc(-c2ccccc2OC)on1>>COc1ccccc1-c1cc(CCCC(=O)O)no1,,C1COCCO1,O,[Li+].[OH-],,test
US05066680,CN(C)CC#CCN(C=O)C(=O)c1ccccc1.C[Mg]Br>>CN(C)CC#CCNC(=O)C(C)(O)c1ccccc1,,C1CCOC1,CCOCC,Cc1ccccc1,[Na+].[OH-],test
US20130102776A1,COc1ccc2c(c1C#CCCN1CCN(C(=O)OC(C)(C)C)CC1)OCC2=O>>COc1ccc2c(c1CCCCN1CCN(C(=O)OC(C)(C)C)CC1)OCC2=O,[Pd],CCO,,,,test
US20140038919A1,CC(C)(C)[Si](C)(C)OCCCCI.CS(=O)(=O)Nc1cc2oc(-c3ccc(F)cc3)c(C#N)c2cc1C1CC1>>CC(C)(C)[Si](C)(C)OCCCCN(c1cc2oc(-c3ccc(F)cc3)c(C#N)c2cc1C1CC1)S(C)(=O)=O,,CC#N,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20100003246A1,COc1cc(B2OC(C)(C)C(C)(C)O2)cnc1N.Fc1ccc(-c2nc(Br)cs2)cc1>>COc1cc(-c2csc(-c3ccc(F)cc3)n2)cnc1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20110257225A1,BrCCOc1ccccc1.NC1CCCCC1>>c1ccc(OCCNC2CCCCC2)cc1,,CCO,,[I-].[K+],O=C([O-])O.[Na+],test
US20090048258A1,CC#N.COc1cccc(C(=O)c2ccccc2N)c1>>COc1cccc(-c2cc(N)nc3ccccc23)c1,,c1ccncc1,,O,[H-].[Na+],test
US04772600,CCNCC.O=C(O)Cn1c(-c2ccc(C(F)(F)F)cc2)nc2cccnc21>>CCN(CC)C(=O)Cn1c(-c2ccc(C(F)(F)F)cc2)nc2cccnc21,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US05003080,C=CC[C@@H]1C[C@H](CC#N)OC2(CCCCC2)O1.O=[O+][O-]>>N#CC[C@H]1C[C@@H](CC=O)OC2(CCCCC2)O1,,ClCCl,,,,test
US20040077669A1,CC#CCOc1cc(Cl)ncn1.Oc1c(Cl)cc(F)cc1Cl>>CC#CCOc1cc(Oc2c(Cl)cc(F)cc2Cl)ncn1,,CN(C)C=O,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20150274767A1,C1COCCO1.C=O.CC(C)(C)[Si](C)(C)O[C@H]1C[C@H](n2cc(Br)c3c(N)ncnc32)O[C@@H]1C=O>>CC(C)(C)[Si](C)(C)O[C@H]1C[C@H](n2cc(Br)c3c(N)ncnc32)CC1(CO)CO,,CCO,CCOC(C)=O,[Na+].[OH-],,test
US20040014802A1,Nc1n[nH]c2cc(Cl)ccc12.O=C(Cl)c1cc(Cl)cc(Cl)c1>>O=C(Nc1n[nH]c2cc(Cl)ccc12)c1cc(Cl)cc(Cl)c1,,c1ccncc1,,,,test
US20120142681A1,CC(=O)OC(C)=O.NN=C(N)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1>>CC(=O)N/N=C(/N)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1,,CS(C)=O,ClCCl,c1ccncc1,,test
US20150119412A1,CO.O=Cc1ccc(-c2ccc(F)cc2F)c(F)c1F>>COc1c(C=O)ccc(-c2ccc(F)cc2F)c1F,,CO,,C[O-].[Na+],,test
US20090264416A1,CC(C)(C)OC(=O)N1CCNCC1.CC(C)(NC(=O)c1cccc(CCl)c1)C(F)(F)F>>CC(C)(C)OC(=O)N1CCN(Cc2cccc(C(=O)NC(C)(C)C(F)(F)F)c2)CC1,,CCOC(C)=O,O,CCN(CC)CC,[I-].[Na+],test
US20070066820A1,Cc1ccc(S(=O)(=O)OC[C@@H]2CCCN2C(=O)OC(C)(C)C)cc1.Oc1ccc(OCc2ccccc2)cc1>>CC(C)(C)OC(=O)N1CCC[C@H]1COc1ccc(OCc2ccccc2)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20050143381A1,N#Cc1ccc(CBr)cc1.O=c1[nH]nc2c(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)cnn12>>N#Cc1ccc(Cn2nc3c(-c4ccc(Cl)cc4)c(-c4ccc(Cl)cc4)cnn3c2=O)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150299178A1,Brc1csc(NC2CC2)n1.CC(=O)Cl>>CC(=O)N(c1nc(Br)cs1)C1CC1,,C1CCOC1,,[H-].[Na+],,test
US04268509,COC(=O)c1nsc(Cl)n1.NC(N)=S>>COC(=O)c1nsc(S)n1,,O,,C1CCOC1,,test
US20040204427A1,CI.O=[N+]([O-])c1ccc(O)cc1F>>COc1ccc(N)c(F)c1,[Pd],CN(C)C=O,CO,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20120184565A1,C=CCO.Cc1ncn(-c2ccc([N+](=O)[O-])cc2F)n1>>C=CCOc1cc([N+](=O)[O-])ccc1-n1cnc(C)n1,,CN(C)C=O,,[H-].[Na+],,test
US20040123400A1,Cn1cc[n+](C)c1N=Nc1ccc(N)cc1.Nc1nc(Cl)cc(Cl)n1.[Cl-]>>Cn1cc[n+](C)c1N=Nc1ccc(Nc2cc(Cl)nc(N)n2)cc1.[Cl-],,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US05578732,Cc1c(OCC(F)(F)F)ccnc1CSc1nc2ccccc2[nH]1.O=C(OO)c1cccc(Cl)c1>>Cc1c(OCC(F)(F)F)ccnc1CS(=O)c1nc2ccccc2[nH]1,,ClC(Cl)Cl,,CCO,O,test
US20100016279A1,C1N2CN3CN1CN(C2)C3.O.c1cc2[nH]ccc2cn1>>O=Cc1c[nH]c2ccncc12,,O,,CC(=O)O,,test
US20060094735A1,Cc1ccc(C2=N[C@@H](CCCNC(=O)OCc3ccccc3)CN2[C@@H](c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1>>Cc1ccc(C2=N[C@@H](CCCN)CN2[C@@H](c2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)C(C)C)cc1,,Br,CC(=O)O,,,test
US05686442,CCOC(=O)c1nnn(Cc2ccc(OC)cc2)c1C(=O)c1cc(C)c(C)cc1[N+](=O)[O-]>>COc1ccc(Cn2nnc(C(=O)O)c2C(=O)c2cc(C)c(C)cc2[N+](=O)[O-])cc1,,C1CCOC1,,[Na+].[OH-],,test
US20110152321A1,CC(C)(C)OC(=O)N[C@@H](CC(N)=O)C(=O)OCc1ccccc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CC(C)(C)OC(=O)N[C@@H](CC(N)=S)C(=O)OCc1ccccc1,,C1CCOC1,,NN,,test
US05468898,COC(=O)c1cc(C(C)O)c2ccc(OCc3ccccc3)cc2c1.O=[Cr](=O)=O>>COC(=O)c1cc(CC(=O)O)c2ccc(OCc3ccccc3)cc2c1,,CC(C)=O,,O=S(=O)(O)O,,test
US20140371199A1,NC1CCN(C(=O)c2ccc(-c3cn4c(-c5ccc(Cl)cc5)cnc4cn3)cc2)CC1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(c1ccc(-c2cn3c(-c4ccc(Cl)cc4)cnc3cn2)cc1)N1CCC(NC(=O)C(F)(F)F)CC1,,CN(C)C=O,,c1ccncc1,,test
US20140221574A1,C=C(C)C(=O)OCCCCCCCl.O=Cc1ccc2cc(O)ccc2c1>>C=C(C)C(=O)OCCCCCCOc1ccc2cc(C=O)ccc2c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100267709A1,N#Cc1c[nH]c(=O)c2c1[nH]c1cc(Cl)ccc12.O=P(Cl)(Cl)Cl>>Cl.N#Cc1cnc(Cl)c2c1[nH]c1cc(Cl)ccc12,,C1COCCO1,,,,test
US20160152626A1,COc1cc2c(cc1C1=NC([Si](C)(C)C)N=N1)-c1c(c(C(=O)N3CCOCC3(C)C)nn1-c1ccsc1)CO2>>COc1cc2c(cc1C1=NCN=N1)-c1c(c(C(=O)N3CCOCC3(C)C)nn1-c1ccsc1)CO2,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06310070B1,ClCc1ccccc1.O=C(O)c1cccc(O)c1>>O=C(OCc1ccccc1)c1cccc(O)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070264600A1,NC1(C2C(=O)N=C3Nc4ccccc4N3C2=O)NC(=C2C(=O)N=C3Nc4ccccc4N3C2=O)c2nc3ccccc3nc21>>O=C1N=C2Nc3ccccc3N2C(=O)C1=c1[nH]c(=C2C(=O)N=C3Nc4ccccc4N3C2=O)c2nc3ccccc3nc12,,O=S(=O)(O)O,,O,,test
US20050107388A1,NC(=O)c1ccc(Cl)nc1.OB(O)c1ccc(F)cc1>>NC(=O)c1ccc(-c2ccc(F)cc2)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20120295885A1,CC(C)(C)c1ccc2c(=O)[nH]ncc2c1.N#Cc1cn(-c2cccc(I)c2C=O)nc1Nc1ccc(C(=O)N2CCOCC2)cc1>>CC(C)(C)c1ccc2c(=O)n(-c3cccc(-n4cc(C#N)c(Nc5ccc(C(=O)N6CCOCC6)cc5)n4)c3C=O)ncc2c1,,CS(C)=O,,O=C([O-])O.[Na+],,test
US04985582,CN(CC1(C2CCCCC2)COC1)C(=O)c1ccc(C#N)cc1>>CN1CC2(C3CCCCC3)COC1(c1ccc(C#N)cc1)OC2,,ClCCl,,CCOCC,FB(F)F,test
US20140179680A1,CC(C)(C)OC(=O)N1CCO[C@@H]2CNCC[C@H]21.O=C(Cl)OCc1ccccc1>>CC(C)(C)OC(=O)N1CCO[C@@H]2CN(C(=O)OCc3ccccc3)CC[C@H]21,,ClCCl,,CCN(CC)CC,,test
US20050059702A1,CS(=O)(=O)Cl.O=[N+]([O-])c1ccccc1S(=O)(=O)N(Cc1ccc(CO)cc1)Cc1ccccn1>>CS(=O)(=O)OCc1ccc(CN(Cc2ccccn2)S(=O)(=O)c2ccccc2[N+](=O)[O-])cc1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20080132495A1,NC(CO)(CO)CO.Nn1ccc(-c2nc3cc(CN4CCOCC4)ccc3[nH]2)n1.O=C=Nc1ccc(F)cc1>>NC(=O)N(c1ccc(F)cc1)c1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1,,C1CCOC1,,,,test
US20100234365A1,CCOC(=O)Cc1nnn(C[C@@H]2OC(=O)N(c3ccc(Cl)cc3)[C@H]2c2cccc(OC)c2)n1>>COc1cccc([C@H]2[C@H](Cn3nnc(CCO)n3)OC(=O)N2c2ccc(Cl)cc2)c1,,CO,,[BH4-].[Na+],,test
US20080070308A1,C1CCOC1.CCOC(=O)/N=N/C(=O)OCC.O=C1NC(=O)c2cc([N+](=O)[O-])ccc21.OCCS>>O=C1c2ccc([N+](=O)[O-])cc2C(=O)N1CCSc1ccccc1,,C1CCOC1,,,,test
US20080167306A1,CCOC(=O)C1(OCc2cccc(Cn3c(C)c(C(=O)c4ccc(C)cc4)c4ccc(OC)cc43)c2)CC1>>COc1ccc2c(C(=O)c3ccc(C)cc3)c(C)n(Cc3cccc(COC4(C(=O)O)CC4)c3)c2c1,,CO,O,C1CCOC1,[Na+].[OH-],test
US20140235439A1,Cc1cc(Cl)ccc1C(N)=NO.O=Cc1ccco1>>Cc1cc(Cl)ccc1C1=NOC(c2ccco2)N1,C1CCNCC1,,,,,test
US04985444,O=C1CCNC(=O)C1.c1ccc(-c2cc3ccccn3n2)cc1>>O=C1C=C(c2c(-c3ccccc3)nn3ccccc23)CCN1,O=S(=O)(O)O,CC(=O)O,,O=C([O-])O.[Na+],,test
US20060217382A1,COc1ccc(Nc2ncc(C(C)NC(=O)Cc3ccccc3)nn2)cc1>>COc1ccc(Nc2ncc3c(C)nc(Cc4ccccc4)n3n2)cc1,,ClCCCl,,O=P(Cl)(Cl)Cl,,test
US20110207728A1,COC(=O)c1cccn1CC(=O)c1cccnc1.NCCN>>O=C1c2cccn2CC2(c3cccnc3)NCCN12,,C1COCCO1,,,,test
US04925591,CCCCCCCCCCCCOc1ccc(C(=O)Oc2ccc(OCc3ccccc3)cc2)cc1Cl>>CCCCCCCCCCCCOc1ccc(C(=O)Oc2ccc(O)cc2)cc1Cl,[Pd],CCOC(C)=O,,[H][H],,test
US20060058282A1,COc1ccc(C2(C(=O)Cl)CCCCC2)cc1.O=C(NOCc1ccccc1)c1ccc(O)cc1>>COc1ccc(C2(C(=O)Oc3ccc(C(=O)NOCc4ccccc4)cc3)CCCCC2)cc1,CN(C)c1ccncc1,C1CCOC1,,CCOC(C)=O,,test
US05502054,CCCC[Sn](CCCC)(CCCC)C(O)CC(C)(C)c1ccc(Cl)cc1.II>>CCCC[Sn](CCCC)(CCCC)C(I)CC(C)(C)c1ccc(Cl)cc1,,CC#N,ClCCl,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US08822453B2,CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(CN(CCn3ccc4oc(C)cc4c3=O)Cc3cccnc3C#N)ccc21.O=CO>>CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(CN(CCn3ccc4oc(C)cc4c3=O)Cc3cccnc3CNC=O)ccc21,[Ni],O=CO,,CC(C)=O,,test
US20100130539A1,Nc1ncccc1Br.O=C(CBr)[C@@H]1CCCN1C(=O)OCc1ccccc1>>O=C(OCc1ccccc1)N1CCC[C@H]1c1cn2cccc(Br)c2n1,,CCO,,,,test
US04714702,Cc1cc(F)ccc1NC(=O)c1cc([N+](=O)[O-])ccc1NC(=O)CF>>Cc1cc(F)ccc1-n1c(CF)nc2ccc([N+](=O)[O-])cc2c1=O,,CC(=O)O,,CCOCC,FB(F)F,test
US20120040020A1,CC(C)(C)OC(=O)N1CC2(CCN(C(=O)OCc3ccccc3)C2)C1>>O=C(OCc1ccccc1)N1CCC2(CNC2)C1,,C1COCCO1,ClCCl,Cl,,test
US20080021056A1,CC(N=[N+]=[N-])c1cn(COCC[Si](C)(C)C)nc1I>>CC(N)c1cn(COCC[Si](C)(C)C)nc1I,,C1CCOC1,O,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090149486A1,COC(=O)[C@H]1CCC[C@@H](CO)C1.Clc1ncc(-c2ccccc2)c(-c2ccccc2)n1>>O=C(O)[C@H]1CCC[C@@H](COc2ncc(-c3ccccc3)c(-c3ccccc3)n2)C1,,CN(C)C=O,,[H-].[Na+],,test
US04472305,CSCC[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C)C(N)=O>>CSCC[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCCN1)C(N)=O,,CC(=O)O,,Cl,,test
US20120208810A1,Clc1ccc2scc(CBr)c2c1.O=c1cc(N2CCOCC2)nc2n1CC[C@@H](C(F)(F)F)N2>>O=c1cc(N2CCOCC2)nc2n1CC[C@@H](C(F)(F)F)N2Cc1csc2ccc(Cl)cc12,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05430027,CC(=O)OC[C@H]1O[C@@H](n2cnc3c(Cl)nc(C)nc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O.NOC1CCCC1>>Cc1nc(NOC2CCCC2)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1,,C1COCCO1,,CCN(CC)CC,Cl,test
US20150239900A1,CCOC(CN)OCC.O=Cc1ccc(Cl)c(Br)c1>>CCOC(CNCc1ccc(Cl)c(Br)c1)OCC,,ClCCl,O,CC(=O)O,[BH3-]C#N.[Na+],test
US20100298336A1,CC(=O)c1ncsc1CBr.Oc1cc(C(F)(F)F)nc(S)n1>>CC(=O)c1ncsc1CSc1nc(O)cc(C(F)(F)F)n1,,CCO,,CCN(CC)CC,,test
US20090181956A1,Nc1ccc(Cl)cc1C(=O)O.O=C1CCC(=O)N1I>>Nc1c(I)cc(Cl)cc1C(=O)O,,O,,CN(C)C=O,,test
US20130053366A1,Cc1ccc2c(c1)c1c(n2C#Cc2cccc3cnccc23)CCN(C)C1>>Cc1ccc2c(c1)c1c(n2CCc2cccc3c2CCNC3)CCN(C)C1,[Pd],CO,,O=C[O-].[NH4+],,test
US20130065880A1,Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)NCCNC(=O)OC(C)(C)C)c[nH]4)c3)cc2F)c1>>Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)NCCN)c[nH]4)c3)cc2F)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090143361A1,COc1ccc2nc(C)c3c(C)nc(-c4cc(Cl)cc(Cl)c4)n3c2n1.OB(O)c1cccs1>>COc1ccc2nc(C)c3c(C)nc(-c4cccs4)n3c2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20090099221A1,CCOC(=O)c1cc(-c2ccnc(N)n2)oc1-c1ccccc1>>Nc1nccc(-c2cc(C(=O)O)c(-c3ccccc3)o2)n1,,CCO,O,Cl,[Na+].[OH-],test
US20130005707A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1noc2cc(Br)ccc12>>CC(C)(C)OC(=O)Nc1noc2cc(Br)ccc12,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US20090221772A1,BrBr.CCC1Cc2cc3c(cc2C1=O)OCO3>>CC1Cc2c(cc3c(c2Br)OCO3)C1=O,,ClCCl,O,CC(=O)[O-].[Na+],,test
US20040162325A1,Cc1ccc(-c2nc(CCCO)c(C(F)(F)F)o2)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(-c2nc(CCCOS(=O)(=O)c3ccc(C)cc3)c(C(F)(F)F)o2)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US20020099047A1,CS(=O)(=O)Cl.OC[C@H]1CCCCN1CCc1ccc2c(c1)OCO2>>Cl[C@@H]1CCCCN(CCc2ccc3c(c2)OCO3)C1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20140038999A1,COc1cncc2c(=O)n(C)c3cc(OC[C@H](CC(C)C)NC(=O)OC(C)(C)C)ccc3c12.O=C(O)C(F)(F)F>>COc1cncc2c(=O)n(C)c3cc(OC[C@@H](N)CC(C)C)ccc3c12.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20100298339A1,O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1cccc(-c2cccc3nc(Nc4ccc(OCCN5CCCC5)cc4)nn23)c1>>O=S(=O)(Oc1cccc(-c2cccc3nc(Nc4ccc(OCCN5CCCC5)cc4)nn23)c1)C(F)(F)F,,ClCCl,,CCN(CC)CC,O,test
US20030013743A1,NNC(=O)c1cccnc1Nc1ccccc1.O=Cc1cccc(C(F)(F)F)c1>>O=C(NN=Cc1cccc(C(F)(F)F)c1)c1cccnc1Nc1ccccc1,,CCO,,O,,test
US20080081813A1,COC(=O)C(Br)c1ccccc1.O=C(Nc1ccc(N2CCNCC2)cc1)c1ccccc1-c1ccc(C(F)(F)F)cc1>>O=C(O)CN1CCNCC1,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20140221333A1,CC1CCC(O)CN1C(=O)OC(C)(C)C.Nc1ncnc2[nH]nc(Br)c12>>CC1CCC(n2nc(Br)c3c(N)ncnc32)CN1C(=O)OC(C)(C)C,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070207994A1,CC(C)OC(=O)Cl.Cn1nccc1-c1cc(N)ccc1OCCN1CCCOCC1>>CC(C)OC(=O)Nc1ccc(OCCN2CCCOCC2)c(-c2ccnn2C)c1,,CS(C)=O,,CC(=O)N(C)C,,test
US20140080822A1,COC(=O)c1c(N)ccc2c1OCC(NCC(OC)OC)=N2>>COC(=O)c1c(N)ccc2c1OCc1nccn1-2,,CO,Cl,,,test
US20080015184A1,CC(C)Cn1c(CN)nc2c(N)nc3ccccc3c21.CN=C=O>>CC(C)Cn1c(CN(C)C(N)=O)nc2c(N)nc3ccccc3c21,,CN(C)C=O,,ClCCl,,test
US20150299120A1,Cc1c(N)ccc(C#N)c1Cl.O=C(Cl)Cl>>Cc1c(N=C=O)ccc(C#N)c1Cl,,ClCCl,,Cc1ccccc1,O=C([O-])O.[Na+],test
US20140294898A1,CC(C)(C)OC(=O)CBr.COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C>>COC(=O)[C@H](Cc1cn(CC(=O)OC(C)(C)C)c2ccccc12)NC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040044008A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1ccc(N2CCN(Cc3ccccc3)CC2)cc1>>CC(C)(C)OC(=O)Nc1ccc(N2CCN(Cc3ccccc3)CC2)cc1,,ClCCl,,CCN(CC)CC,,test
US20060079548A1,CCc1cc2ccc(OC)cc2[nH]1.CI.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCc1c(C(=O)C(F)(F)F)c2ccc(OC)cc2n1C,,C1CCOC1,,[H-].[Na+],,test
US04954485,O=C(c1ccccc1)C(O)[C@@H]1CC[C@H](n2ccc(=O)[nH]c2=O)O1.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>O=C(c1ccccc1)C(O)[C@@H]1CC[C@H](n2ccc(=S)[nH]c2=O)O1,,O,,c1ccncc1,,test
US20110021515A1,C1CC2CNCC1O2.CC1(C)OCc2c(Cl)nc(-c3ccc(Br)cc3)nc21>>CC1(C)OCc2c(N3CC4CCC(C3)O4)nc(-c3ccc(Br)cc3)nc21,,ClCCl,,CCN(CC)CC,Cl,test
US20140303142A1,CC(C)C(Nc1cncc(-c2c[nH]c3ncc(CN)cc23)c1)C(=O)NCC(F)(F)F.O=C(Cl)C1CCCC1>>CC(C)C(Nc1cncc(-c2c[nH]c3ncc(CNC(=O)C4CCCC4)cc23)c1)C(=O)NCC(F)(F)F,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US20110294876A1,CC1CCCC(O)C1C.CCC(C)N=C=O>>CCC(C)NC(=O)OC1CCCC(C)C1C,,O,,,,test
US04169108,COc1cc2ccc(CC(=O)O)cc2c(C)c1OC.O=S(Cl)Cl>>COc1cc2ccc(CC(=O)Cl)cc2c(C)c1OC,,c1ccccc1,,,,test
US20120329780A1,CN1CCN(c2ccc(N)cc2)CC1.COc1ccc(Cn2cc3nc(-c4cscn4)nc(Cl)c3n2)cc1>>CN1CCN(c2ccc(Nc3nc(-c4cscn4)nc4cn[nH]c34)cc2)CC1,C1COCCO1,CO,,Cl,,test
US20130053396A1,CC(C)(C)OC(=O)N1CCN(c2nc(-c3ccc4ccccc4n3)ns2)CC1.Cl>>[Cl-].c1ccc2nc(-c3nsc(N4CC[NH2+]CC4)n3)ccc2c1,,CO,,,,test
US20150291572A1,CC(C)Oc1ccc(C2CC(OS(C)(=O)=O)CCO2)cn1.FC(F)(F)c1cccc(S)c1>>CC(C)Oc1ccc(C2CC(Sc3cccc(C(F)(F)F)c3)CCO2)cn1,,CC#N,,N#N,O=C([O-])[O-].[K+].[K+],test
US04788205,CCOC(=O)CC(=O)CCl.Cc1nc(C)n(CCO)c1C>>CCOC(=O)CC(=O)COCCn1c(C)nc(C)c1C,,C1CCOC1,,Cl,[H-].[Na+],test
US20120083513A1,Cn1nnc2c(C(=N)SCC(=O)C(=O)O)ncn2c1=O.NC1CC1>>Cn1nnc2c(-c3nc(C(=O)NC4CC4)cs3)ncn2c1=O,,C1CCOC1,,CC(C)COC(=O)Cl,CCN(CC)CC,test
US06872718B1,CO.Cc1ccc(C)c([N+](=O)[O-])c1>>COc1cc(C)c(N)cc1C,[Pd],O=S(=O)(O)O,,,,test
US05449686,COc1ccc(C2(CO)CCC(OC)(OC)CC2)cc1OC1CCCC1>>COc1ccc(C2(CO)CCC(=O)CC2)cc1OC1CCCC1,,CCOCC,,Cl,,test
US20060189605A1,CCOCC.CC[Mg]Br.Cc1cccc(C(=O)O)c1N>>CCC(O)(CC)c1ccccc1N,,C1CCOC1,,Cl,[Cl-].[NH4+],test
US20090221611A1,CI.C[C@@H](O[C@H]1CC(=S)NC[C@@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CSC1=NC[C@H](c2ccc(F)cc2)[C@@H](O[C@H](C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1,,C1CCOC1,,[H-].[Na+],,test
US05905088,C=C(C(=O)OCC)c1csc(C2(C)COc3cc4c(cc32)C(C)(C)CCC4(C)C)c1>>C=C(C(=O)O)c1csc(C2(C)COc3cc4c(cc32)C(C)(C)CCC4(C)C)c1,,C1CCOC1,,Cl,[Li+].[OH-],test
US20120258982A1,COC(=O)c1ccc(Cc2cn(-c3ccccn3)c3cc(Cl)ccc3c2=O)cc1>>O=C(O)c1ccc(Cc2cn(-c3ccccn3)c3cc(Cl)ccc3c2=O)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US20160143870A1,CC(C)CNCC(C)C.O=[N+]([O-])c1cc(Br)ccc1F>>CC(C)CN(CC(C)C)c1ccc(Br)cc1[N+](=O)[O-],,CCOC(C)=O,,,,test
US20120269724A1,CC(C)(C)OC(=O)NCCN.CC(C)(C)Oc1ccccc1C=O>>CC(C)(C)OC(=O)NCCNCc1ccccc1OC(C)(C)C,,CC#N,,[BH4-].[Na+],,test
US03943176,CC(C)CSC1=C(O)CC(C)(C)CC1=O.OO>>CC(C)CS(=O)C1=C(O)CC(C)(C)CC1=O,,CCCCCC,,CC(=O)O,,test
US20120208817A1,CCOc1cc(C=O)cc([N+](=O)[O-])c1O.COc1cccc(CC(=O)c2ccc(F)cc2)c1.NC(N)=O>>CCOc1cc(C2NC(=O)NC(c3ccc(F)cc3)=C2c2cccc(OC)c2)cc([N+](=O)[O-])c1O,,CCO,CCOC(C)=O,Cl,,test
US04590203,COC(=O)c1cc(C)c(OCCO)s1>>COC(=O)c1ccc(OCCO)s1,,c1ccccc1,,,,test
US20100087417A1,Cc1cc(C(N)=O)cc(C)c1CCC(=O)OC(C)(C)C>>Cc1cc(C#N)cc(C)c1CCC(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US20090062251A1,COC(=O)c1ccc2c(c1)c1c(n2C)CC[C@@H](C2CCOCC2)C1>>Cn1c2c(c3cc(C(=O)O)ccc31)C[C@H](C1CCOCC1)CC2,,C1COCCO1,,[Li+].[OH-],,test
US04859661,O=[N+]([O-])O.Oc1ccc(C2CCCCC2)cc1>>O=[N+]([O-])c1cc(C2CCCCC2)ccc1O,,O,,CCOCC,,test
US20140235620A1,CC(C)[C@H]1COC(=O)N1c1ccnc(Cl)n1.C[C@H](N)c1ccc(C(=O)NC2CCCCC2)c(F)c1>>CC(C)[C@H]1COC(=O)N1c1ccnc(N[C@@H](C)c2ccc(C(=O)NC3CCCCC3)c(F)c2)n1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US06002043,CCCCCCCCCCCCCCCCCC(=O)O.O=C(Cl)Cl>>CCCCCCCCCCCCCCCCCC(=O)Cl,,Clc1ccccc1,,,,test
US20160159740A1,Brc1ccccc1.CC(C)(C)OC(=O)n1cc(C=O)c2ccccc21>>CC(C)(C)OC(=O)n1cc(C(O)c2ccccc2)c2ccccc21,,C1CCOC1,,[Mg],,test
US05106871,COC(=O)CBr.COc1ccc(C(=O)CCc2ccc(O)cc2)c(O)c1CCC(C)C>>COC(=O)COc1ccc(CCC(=O)c2ccc(OC)c(CCC(C)C)c2O)cc1,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20020165245A1,C=CCOc1cc([N+](=O)[O-])ccc1OC>>C=CCOc1cc([N+](=O)[O-])ccc1O,,CS(C)=O,,[Na+].[OH-],,test
US20140243526A1,C=C1CCCC(C)(C)[C@@H](C=O)[C@H]1CCC(C)=O>>C=C1CCCC(C)(C)[C@@H](CO)[C@H]1CCC(C)=O,,Cc1ccccc1,,,,test
US20070021445A1,CC(C)(C)C(=O)OC(=O)C(C)(C)C.Nc1nc(O)c2ccc(-c3c(F)cccc3C(F)(F)F)nc2n1>>CC(C)(C)C(=O)Nc1nc(O)c2ccc(-c3c(F)cccc3C(F)(F)F)nc2n1,,c1ccncc1,,,,test
US05514680,NOS(=O)(=O)O.O=c1[nH]c2cc(Br)c(Br)c([N+](=O)[O-])c2[nH]c1=O>>Nn1c(=O)c(=O)[nH]c2c([N+](=O)[O-])c(Br)c(Br)cc21,,O,,[K+].[OH-],,test
US20060106029A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2cccc(C(F)(F)F)c2F)CC1.Cl>>Cl.O=C(c1cccc(C(F)(F)F)c1F)N1CCNCC1,,CO,,C1COCCO1,,test
US20110224254A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1=C(O)C(=O)N(c2ccc3[nH]cnc3c2)C1c1cccc(F)c1F>>CC1=C(O)C(=O)N(c2ccc3c(c2)ncn3C(=O)OC(C)(C)C)C1c1cccc(F)c1F,,C1CCOC1,,CCN(CC)CC,Cl,test
US20090192332A1,CC(=O)N[C@@H](CS)C(=O)O.CC(C)=CCCC(C)=CCCC(C)=CCBr>>CC(=O)N[C@@H](CSCC=C(C)CCC=C(C)CCC=C(C)C)C(=O)O,,CC(C)O,,O=C([O-])[O-].[Na+].[Na+],,test
US20060178513A1,Nc1ccccc1I.O=C(Cl)c1ccccc1C(F)(F)F>>NC(=O)c1ccccc1C(F)(F)F,,C1CCOC1,,CCN(CC)CC,,test
US20040142979A1,BrCCOCCBr.CCCCOc1ccc(-c2ccc(S(=O)(=O)CC(=O)OC(C)(C)C)s2)cc1>>CCCCOc1ccc(-c2ccc(S(=O)(=O)C3(C(=O)OC(C)(C)C)CCOCC3)s2)cc1,,CN(C)C=O,O,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US20050107408A1,COC(=O)COc1ccc(F)cc1F.CSc1ncc(C=O)c(NC[C@H](C)O)n1>>CSc1ncc2cc(Oc3ccc(F)cc3F)c(=O)n(C[C@H](C)O)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140275030A1,Cc1noc(C)c1-c1ccc2nc(N3CCN(C(=O)[O-])CC3)n3c2c1OCC3c1ccccc1>>Cc1noc(C)c1-c1ccc2nc(N3CCNCC3)n3c2c1OCC3c1ccccc1,,Cl,,,,test
US20100305096A1,CI.C[C@@H]1COCCN1c1nc(Cl)nc2[nH]cnc12>>C[C@@H]1COCCN1c1nc(Cl)nc2c1ncn2C,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20020055639A1,CCOC(=O)C(=O)CBr.Cn1nc(-c2nc(N)c(Cl)cc2F)c(Cl)c1OC(F)F>>CCOC(=O)c1cn2c(-c3nn(C)c(OC(F)F)c3Cl)c(F)cc(Cl)c2n1,,CCO,,,,test
US04673466,CCCCCCO.COC(=O)c1ccccc1>>CCCCCCO.CCCCCCOC(C)=O,,O,,,,test
US06025375,Cc1ccc(C(=O)C(O)c2ccc(C)cc2)cc1.NC=O>>Cc1ccc(-c2ncoc2-c2ccc(C)cc2)cc1,,O,,O=P(Cl)(Cl)Cl,,test
US20100075948A1,CC(C)(C)[Si](C)(C)OCCOc1ccc(Cl)cc1C=O.N#CCc1ccc(Cl)cc1F>>CC(C)(C)[Si](C)(C)OCCOc1ccc(Cl)cc1/C=C(\C#N)c1ccc(Cl)cc1F,,CO,,C[O-].[Na+],,test
US20140221343A1,CSc1cc2c(cc1Sc1nc3c(N)nccc3n1CCNC(=O)OC(C)(C)C)OCO2>>CSc1cc2c(cc1Sc1nc3c(N)nccc3n1CCN)OCO2,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20020025960A1,CI.COC(=O)C1=NNc2ccc(C)cc2S1(=O)=O>>COC(=O)C1=NN(C)c2ccc(C)cc2S1(=O)=O,,CN(C)C=O,,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20150342185A1,COc1cc(Br)cc(Cl)c1[Pb](OC(C)=O)(OC(C)=O)OC(C)=O.CSCCC1CC(=O)CC(=O)C1>>COc1cc(Br)cc(Cl)c1C1C(=O)CC(CCSC)CC1=O,CN(C)c1ccncc1,ClC(Cl)Cl,,Cc1ccccc1,Cl,test
US20110275611A1,CNc1nc(Cl)cc(N2C[C@@H](CO)OC[C@H]2C)n1.CS(=O)(=O)Cl>>CNc1nc(Cl)cc(N2C[C@@H](COS(C)(=O)=O)OC[C@H]2C)n1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20120269724A1,COc1ccccc1CN(CCCCCCBr)Cc1ccccn1.c1ccc(C2CCNCC2)cc1>>COc1ccccc1CN(CCCCCCN1CCC(c2ccccc2)CC1)Cc1ccccn1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070117986A1,CC(=O)O[C@H]1C[C@@H](C)N(C(=O)OC(C)(C)C)C1>>C[C@@H]1C[C@H](O)CN1C(=O)OC(C)(C)C,,C1CCOC1,CO,O,[Na+].[OH-],test
US20080009524A1,CS(N)(=O)=O.Cc1ccc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)cc1-c1cccc(C(=O)O)c1>>Cc1ccc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)cc1-c1cccc(C(=O)NS(C)(=O)=O)c1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US04794108,CC(C)(C)OC(=O)N[C@@H]1C(=O)N(O)[C@@H]1COC(N)=O.O=C(CBr)OCc1ccc([N+](=O)[O-])cc1>>CC(C)(C)OC(=O)N[C@@H]1C(=O)N(OCC(=O)OCc2ccc([N+](=O)[O-])cc2)[C@@H]1COC(N)=O,,CC#N,,CCN(CC)CC,,test
US20150175601A1,C=CC(=O)Nc1cccc(-c2cccc3cnc(Cl)nc23)c1.CN1CCC(Oc2ccc(N)c(F)c2)CC1>>C=CC(=O)Nc1cccc(-c2cccc3cnc(Nc4ccc(OC5CCN(C)CC5)cc4F)nc23)c1,,CCCCO,,O=C(O)C(F)(F)F,,test
US20090203657A1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cc(C(=O)O)ccn1.C[C@H]1CN(Cc2cccc(-c3cc(CN)ccc3F)c2)CCN1C(=O)OC(C)(C)C>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1ccnc(C(=O)NCc2ccc(F)c(-c3cccc(CN4CCN(C(=O)OC(C)(C)C)[C@@H](C)C4)c3)c2)c1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070060629A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1onc(-c2ccccc2)c1-c1cccc(N)c1>>Cc1onc(-c2ccccc2)c1-c1cccc(NC(=O)OC(C)(C)C)c1,,C1COCCO1,,O=C(O)CC(O)(CC(=O)O)C(=O)O,,test
US20140023611A1,COC(=O)c1cccc(Cc2nc(CCOC(C)=O)cs2)c1>>O=C(O)c1cccc(Cc2nc(CCO)cs2)c1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20150057265A1,CC(C)(C)OC(=O)N[C@H]1CCCN(c2ccncc2N)C1.CC(C)(C)OC(=O)Nc1oc2cccnc2c1C(=O)O>>CC(C)(C)OC(=O)Nc1oc2cccnc2c1C(=O)Nc1cnccc1N1CCC[C@H](NC(=O)OC(C)(C)C)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100009959A1,C#CCBr.COC(=O)c1ccc2c(C3CCCCC3)c(-c3ccccc3CO[Si](C(C)C)(C(C)C)C(C)C)[nH]c2c1>>C#CCn1c(-c2ccccc2CO[Si](C(C)C)(C(C)C)C(C)C)c(C2CCCCC2)c2ccc(C(=O)OC)cc21,,CCOCC,,CN(C)C=O,,test
US07479575B2,CCCCCCc1ccccc1.O=C(Cl)Cc1ccc(Br)cc1>>CCCCCCc1ccc(C(=O)Cc2ccc(Br)cc2)cc1,,Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20120309773A1,Nc1ccncc1.O=C(O)c1cc(Nc2nc(Cl)nc3ccoc23)n[nH]1>>O=C(Nc1ccncc1)c1cc(Nc2nc(Cl)nc3ccoc23)n[nH]1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05124324,CCCCCI.CN1CCCCC1COC(=O)c1c[nH]c2ccccc12>>CCCCCn1cc(C(=O)OCC2CCCCN2C)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20050009907A1,COC(CBr)OC.COc1ccc(-c2ccc(C)c(O)c2)cc1>>COc1ccc(-c2ccc(C)c(OCC(OC)OC)c2)cc1,,C1CCOC1,,[H-].[Na+],,test
US05260316,NO.O=CCOc1ccc2c(c1)CCN(Cc1ccc(-c3ccc(F)cc3)cc1)C2=O>>O=C1c2ccc(OCC=NO)cc2CCN1Cc1ccc(-c2ccc(F)cc2)cc1,,CCO,c1ccncc1,Cl,,test
US20070213336A1,CC1(Br)CC1.CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2O)c1>>CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2OCC2CC2)c1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040138300A1,CCOC(=O)[C@H](Cc1ccc(OCCCCc2ccc([N+](=O)[O-])cc2)cc1)OCC>>CCO[C@@H](Cc1ccc(OCCCCc2ccc([N+](=O)[O-])cc2)cc1)C(=O)O,,C1CCOC1,O,[Li+].[OH-],,test
US04960776,CN(C)CCNC(=O)N1CCN(c2ccc(F)cc2)CC1.Fc1ccc(N2CCNCC2)cc1.NCCN1CCCC1>>O=C(NCCN1CCCC1)N1CCN(c2ccc(F)cc2)CC1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US05789406,COc1ccccc1N=C=O.Nc1ccc2c(c1)Cc1c-2[nH]c(=O)c2nccn12>>COc1ccccc1NC(=O)Nc1ccc2c(c1)Cc1c-2[nH]c(=O)c2nccn12,,CCN(CC)CC,,Cl,,test
US20140148468A1,CCOC(=O)c1sc(C)nc1S.Fc1ccc(C(F)(F)CCBr)cc1>>CCOC(=O)c1sc(C)nc1SCCC(F)(F)c1ccc(F)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150315187A1,COc1ccc(-c2c(-c3ccc(C#N)c(F)c3)nc(N3CCC(NC(=O)OC(C)(C)C)CC3)n(CC(=O)O)c2=O)cc1.[NH4+]>>COc1ccc(-c2c(-c3ccc(C#N)c(F)c3)nc(N3CCC(NC(=O)OC(C)(C)C)CC3)n(CC(N)=O)c2=O)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04221794,O.OCCn1cnc2c(Cl)ncnc21>>O=c1[nH]cnc2c1ncn2CCO,,O,,CC(=O)O,[Na+].[OH-],test
US20070219229A1,COC(=O)Cc1c(C(=O)OC)cc(C)n1C.COC=O>>COC(=O)c1cc(C)n(C)c1C(C=O)C(=O)OC,,C1CCOC1,,CO,[H-].[Na+],test
US20090093483A1,C[C@H](NC(=O)C1=C(O)c2ccc(Br)cc2C(C)(C)C1=O)C(=O)OC(C)(C)C>>C[C@H](NC(=O)C1=C(O)c2ccc(Br)cc2C(C)(C)C1=O)C(=O)O,,O,,O=C(O)C(F)(F)F,,test
US20140113882A1,CCN=C=O.N[C@H](CNc1nc(-c2ccncc2)nc2cnccc12)Cc1ccccc1>>CCNC(=O)NC(CNc1nc(-c2ccncc2)nc2cnccc12)Cc1ccccc1,,ClCCl,,,,test
US20070299116A1,Br.CC(C)(C)OC(=O)NC(Cc1ccc([N+](=O)[O-])cc1)C(=O)C=[N+]=[N-]>>CC(C)(C)OC(=O)NC(Cc1ccc([N+](=O)[O-])cc1)C(=O)CBr,,C1CCOC1,,,,test
US20040006099A1,S=C=Nc1ccccc1.c1cc(N2CCC(COc3ccc4c(c3)CNCC4)CC2)ccn1>>S=C(Nc1ccccc1)N1CCc2ccc(OCC3CCN(c4ccncc4)CC3)cc2C1,,ClCCl,,,,test
US20090275606A1,CCOC(=O)c1c(O)cc(=O)n2c1CCC2.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)c1c(OS(=O)(=O)C(F)(F)F)cc(=O)n2c1CCC2,,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US20020115826A1,Nc1ccccc1N.O=C(O)CCCCCCC(=O)c1ccc2ccccc2c1>>Nc1ccccc1NC(=O)CCCCCCC(=O)c1ccc2ccccc2c1,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20040198982A1,COc1ccc(COC(=O)[C@H](CC(C)C)Nc2nn(C)cc2Br)cc1>>CC(C)C[C@H](Nc1nn(C)cc1Br)C(=O)O,,CO,,Cl,[Li+].[OH-],test
US20100292212A1,CCOC(=O)C1CCN(C(=O)OC(C)(C)C)CC1.COCCCBr>>CCOC(=O)C1(CCCOC)CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US05095012,NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(CCl)CS[C@H]12.Nc1nc(/C(=N/OC(C(=O)OC(c2ccccc2)c2ccccc2)c2ccc(O)c(O)c2)C(=O)On2nnc3ccccc32)cs1>>Nc1nc(/C(=N/OC(C(=O)OC(c2ccccc2)c2ccccc2)c2ccc(O)c(O)c2)C(=O)NC2C(=O)N3C(C(=O)OC(c4ccccc4)c4ccccc4)=C(CCl)CS[C@H]23)cs1,,C1CCOC1,CCOC(C)=O,,,test
US20150158815A1,NC(=O)C(Nc1cncc(Br)c1)c1ccsc1.OB(O)c1cc(Cl)ccc1F>>NC(=O)C(Nc1cncc(-c2cc(Cl)ccc2F)c1)c1ccsc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20100093668A1,CCN(C(C)C)C(C)C.Fc1cnc(Cl)nc1Cl.Nc1ccc(F)cc1>>Cc1cc(Nc2nc(Cl)ncc2F)ccc1F,,CCCCO,,,,test
US05231102,CO[C@@H]1Nc2cc(Cl)cc(Cl)c2[C@@H](NC(=O)Cc2ccccc2)C1=C=O.O>>O=C(Cc1ccccc1)N[C@H]1C[C@H](C(=O)O)Nc2cc(Cl)cc(Cl)c21,,O,,C1CCOC1,[Li+].[OH-],test
US20110263647A1,CC(C)(C)OC(=O)N[C@H](CCc1nccs1)Cc1ccc(C(F)(F)F)cc1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N[C@H](CCc1ncc(Br)s1)Cc1ccc(C(F)(F)F)cc1,,CN(C)C=O,,,,test
US20150191483A1,C=CC1(O)CCC(C(=O)OCC)CC1.O=[O+][O-]>>CCOC(=O)C1CCC(O)(C=O)CC1,,ClCCl,,CSC,,test
US20130089512A1,CS(=O)(=O)Cl.C[Si](C)(C)CCOCn1c(=O)n([C@@H]2CCCNC2)c2nc(-c3cnc4ccc(F)cn34)ncc21>>C[Si](C)(C)CCOCn1c(=O)n([C@@H]2CCCN(S(C)(=O)=O)C2)c2nc(-c3cnc4ccc(F)cn34)ncc21,,ClCCl,,,,test
US20090012125A1,COC(=O)c1ccc(N=C=S)cc1.NNC(=O)CCC(=O)NC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1>>COC(=O)c1ccc(Nc2nnc(CCC(=O)NC3CCN(Cc4ccc(Cl)c(Cl)c4)CC3)o2)cc1,,CN(C)C=O,,,,test
US06211199B1,COc1cc(CN2CCC(CCCO)(Cc3ccc(F)cc3)C2=O)cc(OC)c1OC.CS(=O)(=O)Cl>>COc1cc(CN2CCC(CCCOS(C)(=O)=O)(Cc3ccc(F)cc3)C2=O)cc(OC)c1OC,,ClCCl,,,,test
US20090093524A1,COC(=O)c1cccc(S)c1.Cc1cc(OCc2c(C(C)C)nnn2-c2c(Cl)cccc2Cl)ccc1C(C)O>>COC(=O)c1cccc(SC(C)c2ccc(OCc3c(C(C)C)nnn3-c3c(Cl)cccc3Cl)cc2C)c1,,Cc1ccccc1,,CCCCP(CCCC)CCCC,,test
US20050049274A1,O=c1[nH]c2ccc(Cl)cc2c(-c2ccccc2)c1-c1cc(CO)no1>>O=Cc1cc(-c2c(-c3ccccc3)c3cc(Cl)ccc3[nH]c2=O)on1,,CC#N,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20080207616A1,Nc1cc([N+](=O)[O-])ccc1Cl>>Nc1ccc(Cl)c(N)c1,[Fe],O,,[Cl-].[NH4+],,test
US20020137782A1,CCO.Cc1ccccc1Nc1nc2ccc(CCC(=O)Nc3ccc([C@H](C)CC(=O)O)cc3)cc2o1>>CCOC(=O)Cc1ccc(N)c(O)c1,[Pd],,,O=C[O-].[NH4+],,test
US04431808,CN1CCC(Cl)CC1.O=Cc1cc(Cl)ccc1Sc1cc(F)ccc1F>>CN1CCC(C(O)c2cc(Cl)ccc2Sc2cc(F)ccc2F)CC1,,C1CCOC1,,[Mg],[Cl-].[NH4+],test
US20020049236A1,CC(C)(C)OC(=O)NC(CC=O)C(=O)OCc1ccccc1.COP(=O)(OC)C(=[N+]=[N-])C(C)=O>>C#CCC(NC(=O)OC(C)(C)C)C(=O)OC,,CCOCC,,CO,O=C([O-])[O-].[K+].[K+],test
US04804663,Br.Cc1nc2n(c(=O)c1CCO)CCCS2>>Cc1nc2n(c(=O)c1CCBr)CCCS2,,CC(=O)O,,,,test
US20040063944A1,CCOC(=O)c1cnc2ccc(C3(c4ccc(Cl)cc4)OCCO3)cc2c1Cl.Oc1cccc(Cl)c1>>CCOC(=O)c1cnc2ccc(C3(c4ccc(Cl)cc4)OCCO3)cc2c1Oc1cccc(Cl)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20060167041A1,COc1ccnc(CSc2nc3cc(C)c(OCC(F)(F)F)nc3[nH]2)c1C.O=C(OO)c1cccc(Cl)c1>>COc1ccnc(CS(=O)c2nc3cc(C)c(OCC(F)(F)F)nc3[nH]2)c1C,,CO,Cc1ccccc1,O=C([O-])O.[Na+],,test
US20080254216A1,CCC(C)=O.COC(=O)C(C)OC>>CCC(=O)CC(=O)C(C)OC,,CC(=O)O,,O,CC(C)(C)[O-].[K+],test
US20130137675A1,O=c1c(-c2ccnn2-c2ccccc2)nn(-c2ccc(-n3cccn3)cc2)c2ccoc12>>O=c1c(-c2ccnn2-c2ccccc2)nn(-c2ccc(-n3cccn3)cc2)c2c1OCC2,[Pd],CCO,,,,test
US20090240052A1,CC(C)(C)OC(=O)c1ccc(-c2ccc(O)cc2)cc1NC(=O)c1ccccc1>>O=C(Nc1cc(-c2ccc(O)cc2)ccc1C(=O)O)c1ccccc1,,O=C(O)C(F)(F)F,,,,test
US20030181519A1,CC(C)(C)[Si](C)(C)Oc1ccc(-c2ccc3c([N+](=O)[O-])c(O)ccc3c2)cc1>>O=[N+]([O-])c1c(O)ccc2cc(-c3ccc(O)cc3)ccc12,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20070167444A1,CN1C(=O)C(F)(F)c2cc([N+](=O)[O-])ccc21>>CN1C(=O)C(F)(F)c2cc(N)ccc21,[Ni],,,,,test
US20100197679A1,CC(C)(C)OC(=O)N[C@@H]1Cc2ncc([N+](=O)[O-])cc2C[C@H]1O>>CC(C)(C)OC(=O)N[C@@H]1Cc2ncc(N)cc2C[C@H]1O,[Pd],CCO,,,,test
US04571394,CSc1ncc(Cc2ccc(C)nc2)c(=O)[nH]1.NCC(O)COc1cccc(CN2CCCCC2)c1>>Cc1ccc(Cc2cnc(NCC(O)COc3cccc(CN4CCCCC4)c3)[nH]c2=O)cn1,,ClC(Cl)Cl,,CCOCC,,test
US20100216813A1,CS(=O)(=O)N1CC[C@H](Nc2ccc(C#N)c(Cl)c2)C1.Clc1ccccc1CBr>>CS(=O)(=O)N1CC[C@H](N(Cc2ccccc2Cl)c2ccc(C#N)c(Cl)c2)C1,,CN(C)C=O,,[H-].[Na+],,test
US20100022613A1,CCOC(=O)Cn1c(C)c(Cc2ccc(S(=O)(=O)Cc3ccccc3)cc2)c2cc(F)ccc21>>Cc1c(Cc2ccc(S(=O)(=O)Cc3ccccc3)cc2)c2cc(F)ccc2n1CC(=O)O,,C1CCOC1,,[K+].[OH-],,test
US20050049262A1,CC(=O)O[C@H](C)CCCCn1c(=O)[nH]c2ncn(C)c2c1=O>>C[C@@H](O)CCCCn1c(=O)[nH]c2ncn(C)c2c1=O,,CO,O,Cl,[K+].[OH-],test
US20060257987A1,CCOC(=O)COc1ccc(OCCC(C)Oc2ccc(CC)cc2C(=O)c2ccccc2)cc1>>CCc1ccc(OC(C)CCOc2ccc(OCC(=O)O)cc2)c(C(=O)c2ccccc2)c1,,CCO,,,,test
US20150191462A1,CC(=O)OC[C@@H]1[C@@H](F)[C@@H](F)CN1C(=O)OCc1ccccc1>>O=C(OCc1ccccc1)N1C[C@H](F)[C@H](F)[C@H]1CO,,C1CCOC1,O,CCOC(C)=O,[Na+].[OH-],test
US20120058988A1,COC(=O)c1nc(-c2ccc(OC)cc2)nc2c1[nH]c1cc(OC)ccc12.N>>COc1ccc(-c2nc(C(N)=O)c3[nH]c4cc(OC)ccc4c3n2)cc1,,CO,,,,test
US20140066453A1,NC(=O)c1cc2c(F)cccc2[nH]1>>NCc1cc2c(F)cccc2[nH]1,,C1CCOC1,,[H-].[Na+],,test
US20120004166A1,CC#CC(CC(=O)OC)c1ccc(OCC(C)COc2ccc(C(F)(F)F)cc2)cc1>>CC#CC(CC(=O)O)c1ccc(OCC(C)COc2ccc(C(F)(F)F)cc2)cc1,,C1CCOC1,CO,Cl,O,test
US04933345,COCc1c(C=O)ncc2c1c1c(OCc3ccccc3)cccc1n2S(=O)(=O)c1ccc(C)cc1.NO>>COCc1c(C=NO)ncc2c1c1c(OCc3ccccc3)cccc1n2S(=O)(=O)c1ccc(C)cc1,,CCO,,Cl,,test
US20150353565A1,CN(C)C=C1C(=O)CCCC1=O.Cc1ccc(S(=O)(=O)NN)cc1>>Cc1ccc(S(=O)(=O)n2ncc3c2CCCC3=O)cc1,,CCO,,CC(=O)O,,test
US20080108638A1,CC(C)(C)OC(=O)Cn1c(SCCC[NH2+]CCc2ccccc2)nc2ccccc21.CCCCC(=O)Cl>>CCCCC(=O)N(CCCSc1nc2ccccc2n1CC(=O)OC(C)(C)C)CCc1ccccc1,,ClCCCl,,CCN(CC)CC,,test
US04616020,CCn1c(=O)c2c(ncn2CC)n(Cc2ccccc2)c1=O>>CCn1c(=O)[nH]c2ncn(CC)c2c1=O,[Pd],CC(=O)O,,C,,test
US20110245205A1,Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc([C@@]3(O)CC[C@H](C(=O)O)C(C)(C)C3)s2)c1.NC(=O)CCC(=O)NBr>>Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cnc([C@@]3(O)CC[C@H](C(=O)O)C(C)(C)C3)s2)c1Br,,ClC(Cl)Cl,,,,test
US05866560,CC(C)(C)OC(=O)N1CCC[C@H]1CSc1ccc(C(F)(F)F)cc1>>FC(F)(F)c1ccc(SC[C@@H]2CCCN2)cc1,,O=C(O)C(F)(F)F,,O=C([O-])O.[Na+],,test
US20150344466A1,CCCCc1noc(C(=O)OCC)n1.NCC1CCOC1>>CCCCc1noc(C(=O)NCC2CCOC2)n1,,CCO,,CCN(C(C)C)C(C)C,Cl,test
US04727080,COC1(OC)CCCO1.Nc1cc(F)c(C(=O)O)cc1F>>O=C(O)c1cc(F)c(-n2cccc2)cc1F,,CC(=O)O,,O,,test
US20040019063A1,CC(C)(C)OC(=O)N1CC[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1CO>>CC(C)(C)OC(=O)N1CC[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1C=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20100173888A1,BrCCCCBr.CC(C)(C)OC(=O)NC1CCC(N)CC1>>CC(C)(C)OC(=O)NC1CCC(N2CCCC2)CC1,,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US20160074528A1,Cl.NCCS.O=[N+]([O-])c1ccc(SSc2ccc([N+](=O)[O-])cn2)nc1>>Cl.NCCSSc1ccc([N+](=O)[O-])cn1,,CN(C)C=O,CO,CC(=O)O,,test
US20070155744A1,BrCc1ccccc1.O=C(NCc1ccc(F)cc1)c1cc(I)nc(OCc2ccccc2)c1O>>O=C(NCc1ccc(F)cc1)c1cc(I)nc(OCc2ccccc2)c1OCc1ccccc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20060258695A1,NC1CC1.O=C(O)C1CC1>>O=C(NC1CC1)C1CC1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20030092720A1,CC(C)(C)OC(=O)Nc1cc(CCC(=O)O)ccn1.N>>CC(C)(C)OC(=O)Nc1cc(CCC(N)=O)ccn1,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US05514680,Nc1cc(C(F)(F)F)c(C(F)(F)F)cc1N.O=C(O)C(=O)O>>O=c1[nH]c2cc(C(F)(F)F)c(C(F)(F)F)cc2[nH]c1=O,,Cl,,,,test
US05462941,Cc1ccsc1Br.O=C1OC(=O)c2ccccc21>>O=C(O)c1ccccc1C(=O)c1ccc(Br)s1,,CC(Cl)Cl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20160264522A1,COC(=O)C1=C(C)N([C@@H](C)c2ccccc2)CC1>>COC(=O)[C@H]1CCN([C@@H](C)c2ccccc2)[C@H]1C,,CC#N,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140364412A1,C[C@H]1CCCN1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4ccc(Cl)c(OCCOC5CCCCO5)c4)c4ccccc43)cn12>>C[C@H]1CCCN1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4ccc(Cl)c(OCCO)c4)c4ccccc43)cn12,,CO,ClCCl,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20070105865A1,CN1C(=O)c2ccccc2C(C)(C)C1=O.O=[N+]([O-])O>>CN1C(=O)c2cc([N+](=O)[O-])ccc2C(C)(C)C1=O,,O=S(=O)(O)O,,,,test
US20120302586A1,CCC(F)(F)c1nc2nc(C)cc(O)n2n1.O=P(Cl)(Cl)Cl>>CCC(F)(F)c1nc2nc(C)cc(Cl)n2n1,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US05760248,C(=NC1CCCCC1)=NC1CCCCC1.CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(N)=O,,CN(C)C=O,,On1nnc2ccccc21,,test
US20100256163A1,C=CCBr.CS(=O)(=O)Oc1cccc(C2CCNCC2)c1F>>C=CCN1CCC(c2cccc(OS(C)(=O)=O)c2F)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05440036,CC1(C)CN(N)c2cc(S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)ccc2O1.COC(=O)Cl>>COC(=O)NN1CC(C)(C)Oc2ccc(S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc21,,c1ccncc1,,Cl,,test
US20140249143A1,O=Cc1cn2c(ccc3c(C(F)(F)F)cc(C(F)(F)F)nc32)n1.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>FC(F)(F)c1cc(C(F)(F)F)c2ccc3nc(-c4cnco4)cn3c2n1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20090023746A1,BrCC1CC1.Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)[nH]ccc2c1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC3CC3)ccc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060252807A1,COC(=O)CC(=O)c1ccc(F)cc1.O=S(=O)(Cl)Cl>>COC(=O)C(Cl)C(=O)c1ccc(F)cc1,,ClC(Cl)(Cl)Cl,,,,test
US20120028961A1,N#Cc1ccc(Cl)nc1.NC1CCCCC1>>N#Cc1ccc(NC2CCCCC2)nc1,,CCCCCC,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20030055071A1,COC(=O)c1nc(C(=O)OC)c2cccnc2c1O.CSc1cc(F)ccc1CN>>COC(=O)c1nc(C(=O)NCc2ccc(F)cc2SC)c(O)c2ncccc12,,Cc1ccccc1,,CN(C)C=O,,test
US20080275054A1,COc1ccc(NC(=O)c2ccc(C)c(N)c2)cc1C(F)(F)F.Cn1ncc2c(Cl)ncnc21>>COc1ccc(NC(=O)c2ccc(C)c(Nc3ncnc4c3cnn4C)c2)cc1C(F)(F)F,,CC(C)(C)O,,,,test
US20100266504A1,CCOC(=O)C1=C(N)C(C)(C)CN(Cc2ccccc2)C1.CCOC(=O)CC(=O)Cl>>CCOC(=O)c1c(O)c2c([nH]c1=O)C(C)(C)CN(Cc1ccccc1)C2,,C1CCOC1,,CCN(CC)CC,,test
US20080139639A1,CN(Cc1cc(Br)n(S(=O)(=O)c2cccnc2)c1)C(=O)OC(C)(C)C.OB(O)c1ccc(F)cc1>>CN(Cc1cc(-c2ccc(F)cc2)n(S(=O)(=O)c2cccnc2)c1)C(=O)OC(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US20020103253A1,CNC(=O)c1oc(C(C)(C)C)cc1N.O=C=Nc1ccc(F)cc1>>CNC(=O)c1oc(C(C)(C)C)cc1NC(=O)Nc1ccc(F)cc1,,Cc1ccccc1,,,,test
US04490292,CN(C)CCCl.O=C1Nc2ccccc2SC1=Cc1ccc(Cl)cc1Cl>>CN(C)CCN1CC(=Cc2ccc(Cl)cc2Cl)Sc2ccccc21.Cl,,CCC(C)=O,,[Na+].[OH-],,test
US20040058978A1,COC(=C1C(=O)N(C(C)=O)c2ccc([N+](=O)[O-])cc21)c1ccccc1.Nc1ccc(Cl)cc1>>O=C1Nc2ccc([N+](=O)[O-])cc2/C1=C(/Nc1ccc(Cl)cc1)c1ccccc1,,ClCCl,,N,,test
US20140228360A1,CCOC(=O)CBr.CS(=O)(=O)c1ccccc1O>>CCOC(=O)COc1ccccc1S(C)(=O)=O,,CC#N,O,O=C([O-])[O-].[K+].[K+],,test
US20070287725A1,CCOCC(=O)Cl.COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)c(C)c(NCc3cc(-c4ccc(F)cc4)no3)c2N)cc1>>CCOCC(=O)Nc1c(N(Cc2ccc(OC)cc2)Cc2ccc(OC)cc2)nc(C)c(C)c1NCc1cc(-c2ccc(F)cc2)no1,,ClCCl,,CCN(CC)CC,,test
US20090270436A1,CCOc1cc(C(=O)OC)cc(OC)c1Br.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>CCOc1cc(C(=O)OC)cc(OC)c1-c1cnn(C)c1,,COCCOC,,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US04024134,CC(=O)SCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)[C@@H](NC=O)[C@H]2SC1.O=P(Cl)(Cl)Cl>>CC(=O)SCC1=C(C(=O)OC(c2ccccc2)c2ccccc2)N2C(=O)[C@@H](N)[C@H]2SC1.Cl,,CCOCC,CO,,,test
US20100137299A1,C=O.O=C1Nc2c(cccc2C(F)(F)F)C1c1cc2c(cc1O)OCO2>>O=C1Nc2c(C(F)(F)F)cccc2C1(CO)c1cc2c(cc1O)OCO2,,C1CCOC1,O,[Na+].[OH-],,test
US20140349994A1,C=CCBr.COC[C@H](C)Nc1c(C(=O)N(C)OC)cnn1Cc1ccc(OC)cc1>>C=CCN(c1c(C(=O)N(C)OC)cnn1Cc1ccc(OC)cc1)[C@@H](C)COC,,C1CCOC1,CN(C)C=O,O,[H-].[Na+],test
US20100152441A1,COC(=O)[C@@H]1CN(C/C=C/c2cc(F)ccc2F)CC[C@@H]1CCCN1C(=O)COc2ccc(OC)cc21>>COc1ccc2c(c1)N(CCCC1CCN(C/C=C/c3cc(F)ccc3F)CC1C(=O)O)C(=O)CO2,,CO,,[Na+].[OH-],,test
US20050119256A1,COC(=O)[C@H](Cc1cc(Cl)c(OCc2cccc3nc(-c4ccccc4)oc23)c(Cl)c1)NC(=O)C(F)(F)F>>N[C@@H](Cc1cc(Cl)c(OCc2cccc3nc(-c4ccccc4)oc23)c(Cl)c1)C(=O)O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US04666697,C=CC=O.CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN>>C=CC=O.CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN,,CS(C)=O,,,,test
US20150045351A1,CC(=O)Cl.CC(C)(C)OC(=O)N1CCc2cccc3c2[C@H](CN3)C1>>CC(=O)N1C[C@@H]2CN(C(=O)OC(C)(C)C)CCc3cccc1c32,,O,,CC(=O)N(C)C,,test
US20030013720A1,O=C(Cc1cc(F)cc(F)c1)NCC1(c2ccc(I)cc2)CCNCC1.O=CC1CC1>>O=C(Cc1cc(F)cc(F)c1)NCC1(c2ccc(I)cc2)CCN(CC2CC2)CC1,,CCOC(C)=O,ClCCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04530715,CC1(C(=O)Cn2cncn2)CC1.O=CC(Cl)(Cl)Cl>>CC1(C(=O)C(C(O)C(Cl)(Cl)Cl)n2cncn2)CC1,,CCOCC,O,CC(=O)O,CC(=O)[O-].[Na+],test
US20090227583A1,CN(C(=O)Cl)c1ccccc1.Nc1ccc2nc(N[C@@H]3CCc4ccccc43)ccc2c1>>CN(C(=O)Nc1ccc2nc(N[C@@H]3CCc4ccccc43)ccc2c1)c1ccccc1,,CCN(CC)CC,,,,test
US20050075339A1,CC1(C)NN(c2ccccc2)NC1=O.O=C(O)C(=O)Cc1c(F)cccc1F>>O=c1[nH]c(=O)n(-c2ccccc2)nc1Cc1c(F)cccc1F,O=S(=O)(O)O,,,C1COCCO1,,test
US20130143843A1,CCOC(=O)C1(C)CC(c2ccc(C)cc2)=C(C#N)C(=O)N1>>Cc1ccc(C2=C(C#N)C(=O)NC(C)(C(=O)O)C2)cc1,,CC(=O)O,,Cl,,test
US20100069416A1,CC(C)(C)[Si](C)(C)OCCCCn1ccc(-c2ccccc2F)nc1=O>>O=c1nc(-c2ccccc2F)ccn1CCCCO,,C1COCCO1,Cl,,,test
US20020165245A1,CC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.Cc1ccc(S(=O)(=O)OC[C@H]2COc3ccc([N+](=O)[O-])c(C=O)c3O2)cc1>>CC(=O)/C=C/c1c([N+](=O)[O-])ccc2c1OC(COS(=O)(=O)c1ccc(C)cc1)CO2,,Cc1ccccc1,,,,test
US20100184809A1,COC(=O)c1cccc(CN(C)c2ncc([N+](=O)[O-])cc2Cl)c1>>COC(=O)c1cccc(CN(C)c2ncc(N)cc2Cl)c1,,CO,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20140221339A1,COC(=O)c1cc([N+](=O)[O-])cc2[nH]cnc12>>COC(=O)c1cc(N)cc2[nH]cnc12,[Pd],CO,,,,test
US04665070,CCOC(=O)Nc1cc([N+](=O)[O-])cc(CC)c1C(=O)O>>CCOc1nc2cc([N+](=O)[O-])cc(CC)c2c(=O)o1,,C1CCOC1,,CCN=C=NCCCN(C)C,Cl,test
US06872718B1,Cc1cc(O)c(C(C)(C)C)cc1N=O>>Cc1cc(O)c(C(C)(C)C)cc1N,,CCO,,NN,O,test
US20090221572A1,CN(Cc1ccccc1)C(=O)/C=C1\CCCc2sccc21>>CN(C/C=C1\CCCc2sccc21)Cc1ccccc1,,C1CCOC1,,[Na+].[OH-],,test
US04440929,CCOC(=O)c1nc(S)n2c1c(=O)n(C)c1cc(C(F)(F)F)ccc12.CI>>CCOC(=O)c1nc(SC)n2c1c(=O)n(C)c1cc(C(F)(F)F)ccc12,,ClCCl,,CCN(CC)CC,,test
US20160221945A1,C=CC[C@@H]1COC[C@H]1O>>C=CCC1COCC1=O,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20140005213A1,COCCOc1ccc2ccc(-c3nnc4ccc([C@H](N5CC[C@](C)(NC(=O)OC(C)(C)C)C5)C(F)(F)F)cn34)nc2c1.Cl.ClCCl>>COCCOc1ccc2ccc(-c3nnc4ccc([C@H](N5CC[C@](C)(N)C5)C(F)(F)F)cn34)nc2c1.Cl.Cl,,C1COCCO1,,,,test
US20040138449A1,CCI.O=C(NCc1ccc(Cl)cc1)c1cnc2ccsc2c1O>>CCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2sccc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100331378A1,COC(=O)c1ncoc1-c1cccc(C(=O)OC(C)(C)C)c1>>COC(=O)c1ncoc1-c1cccc(C(=O)O)c1,,O=C(O)C(F)(F)F,,N#N,,test
US20140163000A1,Cn1ccc(-c2ccncc2NC(=O)OC(C)(C)C)cc1=O>>CN1CCC(c2ccncc2NC(=O)OC(C)(C)C)CC1=O,[Pd],CCO,,,,test
US20160002175A1,NCCCN1CCCC1=O.Nc1nc(Cl)cc(Cl)n1>>Nc1nc(Cl)cc(NCCCN2CCCC2=O)n1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20050124626A1,Cc1ccc2ccc(I)cc2[n+]1[O-].O=P(Cl)(Cl)Cl>>Cc1cc(Cl)c2ccc(I)cc2n1,,ClCCl,,N,O,test
US20110281854A1,CN(C)C=O.C[C@@H]1CN(c2ccc3c(n2)NC(=O)CO3)[C@H](c2ccccc2)CO1>>C[C@@H]1CN(c2nc3c(cc2C#N)OCC(=O)N3)[C@H](c2ccccc2)CO1,,CN(C)C=O,,O=C1CCC(=O)N1Br,,test
US20140349991A1,Br[Mg]C1CC1.CCC(=O)N1CCC(c2oc3c(C=O)c(OCc4ccccc4)ccc3c(=O)c2C)CC1>>CCC(=O)N1CCC(c2oc3c(C(O)C4CC4)c(OCc4ccccc4)ccc3c(=O)c2C)CC1,,C1CCOC1,,Cl,O,test
US20040102435A1,COc1ccc(C(=O)Nc2ccc(OC)cc2Cl)cc1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COc1ccc(C(=S)Nc2ccc(OC)cc2Cl)cc1,,Clc1ccccc1,,,,test
US04956379,COC(=O)CBr.Oc1cccc(CCc2cc(-c3ccccc3)n(-c3ccccc3)n2)c1>>COC(=O)COc1cccc(CCc2cc(-c3ccccc3)n(-c3ccccc3)n2)c1,,CC#N,,[I-].[K+],,test
US04273932,CCOC(=O)c1cnc2c(c1O)C(=O)CCC2.NO>>CCOC(=O)c1cnc2c(c1O)C(=NO)CCC2,,CCO,,Cl,,test
US04348327,CC(=O)OC(C)=O.C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC[C@]2(O)C#N>>C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC[C@]2(O)C(N)=O,,CC(=O)O,CC(=O)OC(C)=O,[O-][Cl+3]([O-])([O-])O,,test
US20090118257A1,Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)N1CCCCC1)O2.O>>CC1=C(C)C(=O)C(CCC(C)(O)C(=O)N2CCCCC2)=C(C)C1=O,,O,,COC(C)(C)C,,test
US20020120007A1,COc1ccc(NC(=O)c2cc(N)ccc2NC(=O)c2ccc(C(C)(C)C)cc2)cc1.CS(=O)(=O)Cl>>COc1ccc(NC(=O)c2cc(NS(C)(=O)=O)ccc2NC(=O)c2ccc(C(C)(C)C)cc2)cc1,,ClCCl,,c1ccncc1,,test
US04645527,CCCCN=C=O.CN(C)S(=O)(=O)c1cccc(Cl)c1S(N)(=O)=O>>CCCCNC(=O)NS(=O)(=O)c1c(Cl)cccc1S(=O)(=O)N(C)C,,CCC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100311730A1,CC(C)(C)OC(=O)N1CCCC(CN)C1.O=[N+]([O-])c1cnc(Br)cc1Cl>>CC(C)(C)OC(=O)N1CCCC(CNc2cc(Br)ncc2[N+](=O)[O-])C1,,CC#N,,CCN(CC)CC,,test
US04988699,COC(=O)C1CCc2nc(N)sc2C1>>Nc1nc2c(s1)CC(C(=O)O)CC2,,O=S(=O)(O)O,,[Na+].[OH-],,test
US06730684B1,CN.COC(=O)c1nn(C)c2ccccc12>>CNC(=O)c1nn(C)c2ccccc12,,CO,,,,test
US04548818,CC(C)(C)Cn1c(N)c(N=O)c(=O)[nH]c1=O>>CC(C)(C)Cn1c(N)c(N)c(=O)[nH]c1=O,,O,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20130217680A1,O=C(O)c1cc(Cl)cc(Br)c1>>OCc1cc(Cl)cc(Br)c1,,C1CCOC1,,B,,test
US20120295915A1,Nc1cnccc1NC[C@@H]1CCN(C(=O)C2CC2)C1.O=Cc1ccc(Br)cc1>>O=C(C1CC1)N1CC[C@@H](Cn2c(-c3ccc(Br)cc3)nc3cnccc32)C1,,CCCCO,,CC(=O)O,,test
US20110077235A1,O=C(Cl)C(=O)Cl.O=C(O)[C@H]1C[C@@H]1c1ccccc1>>O=C(Cl)[C@H]1C[C@@H]1c1ccccc1,,ClCCl,,,,test
US20160221946A1,CNC(=O)c1c[nH]c2cc(Br)ccc12.O=S(=O)(Cl)c1cccc(C(F)(F)F)c1>>CNC(=O)c1cn(S(=O)(=O)c2cccc(C(F)(F)F)c2)c2cc(Br)ccc12,,CN(C)C=O,,O,[H-].[Na+],test
US20070254898A1,Cc1nc(Cl)c2sc(C)c(-c3c(C)cc(Br)cc3C)c2n1.OCC1CCNCC1>>Cc1nc(N2CCC(CO)CC2)c2sc(C)c(-c3c(C)cc(Br)cc3C)c2n1,,CCO,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20060094767A1,CC(C)(C)OC(=O)N1CCN(c2ccc(OC[C@@]3(C)Cn4cc([N+](=O)[O-])nc4O3)cc2)CC1.CCOC(=O)Cl>>CCOC(=O)N1CCN(c2ccc(OC[C@@]3(C)Cn4cc([N+](=O)[O-])nc4O3)cc2)CC1,,ClCCl,O,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20140163023A1,CN(C)CC(=O)O.C[C@H]1COCCN1c1nc2c(c(-c3ccc(NC(=O)NC4CC4)cc3)n1)CNC2>>C[C@H]1COCCN1c1nc2c(c(-c3ccc(NC(=O)NC4CC4)cc3)n1)CN(C(=O)CN(C)C)C2,,CN(C)C=O,ClCCl,CCN(CC)CC,ClCCCl,test
US20130190289A1,COC(=O)c1sc(C#CC(C)(C)C)cc1N(CC(=O)N1CCSCC1)C(=O)[C@@H]1CC[C@@H](C)CC1>>C[C@@H]1CC[C@@H](C(=O)N(CC(=O)N2CCSCC2)c2cc(C#CC(C)(C)C)sc2C(=O)O)CC1,,C1CCOC1,O,Cl,[Li]O,test
US20110237517A1,CC(C)(C)OC(=O)NC(C(=O)N1CCC2C1C(c1c[nH]c3cc(F)ccc13)CN2C1CCCC1)C(C)(C)C>>CC(C)(C)C(N)C(=O)N1CCC2C1C(c1c[nH]c3cc(F)ccc13)CN2C1CCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100311965A1,COC(=O)c1cc([N+](=O)[O-])cc2[nH]ncc12>>O=C(O)c1cc([N+](=O)[O-])cc2[nH]ncc12,,C1CCOC1,CO,Cl,[Na+].[OH-],test
US20080188521A1,COCOc1cc(C)ccc1C(O)c1nccs1>>COCOc1cc(C)ccc1C(=O)c1nccs1,O=[Mn]=O,ClCCl,,,,test
US20110257100A1,COCCN(CCn1cc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)cn1)C(=O)OC(C)(C)C.NC1CC1.O=C(Cl)Oc1ccccc1>>COCCN(CCn1cc(-c2cc3nccc(Oc4ccc(NC(=O)NC5CC5)cc4F)c3s2)cn1)C(=O)OC(C)(C)C,,CN(C)C=O,,c1ccncc1,,test
US20070208003A1,COC(=O)CCCBr.COC(=O)c1cscc1NC(=O)OC(C)C>>COC(=O)CCCN(C(=O)OC(C)C)c1cscc1C(=O)OC,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20140061548A1,CC1(C)c2ccccc2N(c2ccc(-c3ccccc3)cc2)c2ccc(Cl)cc21.OB(O)c1ccccc1>>CC1(C)c2ccccc2N(c2ccc(-c3ccccc3)cc2)c2ccc(-c3ccccc3)cc21,,C1COCCO1,,[Cs+].[F-],,test
US20130345192A1,CC(C)(C)OC(=O)N[C@@H]1CCCN(Cc2ccccc2)C1>>CN[C@@H]1CCCN(Cc2ccccc2)C1,,C1CCOC1,CCOC(C)=O,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US06350892B1,COC(=O)CCc1ccc(O)cc1.OCCSCCOC(c1ccc(Cl)cc1)c1ccc(Cl)cc1>>COC(=O)CCc1ccc(OCCSCCOC(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1,,CCOC(C)=O,c1ccccc1,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030017278A1,CCCCCBr.OCCCCOc1cccc(F)c1F>>CCCCCOCCCCOc1cccc(F)c1F,,CN(C)C=O,,[H-].[Na+],,test
US20080318977A1,Cc1cc(N)[nH]n1.O=C(OC(=Cc1ccncc1)c1ccc(F)cc1)c1ccc(F)cc1>>Cc1cc2nc(-c3ccc(F)cc3)c(-c3ccncc3)c(-c3ccc(F)cc3)n2n1,Cl,CCO,,,,test
US04690931,COC(=O)c1cc(C(=O)C(C)Br)ccc1O.c1ccc(CC2CCNCC2)cc1>>COC(=O)c1cc(C(=O)C(C)N2CCC(Cc3ccccc3)CC2)ccc1O,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140315888A1,Cc1nc2nc(N3CC(N(C)C(=O)OC(C)(C)C)C3)c3nncn3c2cc1Br>>CNC1CN(c2nc3nc(C)c(Br)cc3n3cnnc23)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050137213A1,COc1ccc(Nc2nc(C)nc3ccccc23)cc1.FC(F)Cl>>COc1ccc(N(c2nc(C)nc3ccccc23)C(F)F)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100029701A1,C=CCCCN1C(=O)N=C(NC2CCCCC2)C12CCN(C(=O)OC(C)(C)C)CC2.Cl.ClCCl>>C=CCCCN1C(=O)N=C(NC2CCCCC2)C12CCNCC2.Cl.Cl,,ClCCl,,,,test
US20090186830A1,CC(C)(C)OC(=O)C1CCC(NC(=O)OCc2ccccc2)CC1>>CC(C)(C)OC(=O)C1CCC(N)CC1,[Pd],C1CCOC1,,[H][H],,test
US20110319394A1,Cn1c(Cl)nc2ccccc21.O=c1n(-c2ccc(O)cc2)c2ncccc2n1C1CC1>>Cn1c(Oc2ccc(-n3c(=O)n(C4CC4)c4cccnc43)cc2)nc2ccccc21,,CN(C)C=O,CO,[H-].[Na+],,test
US20050256137A1,COC(=O)[C@@H](Cc1ccccc1)OS(C)(=O)=O.O=C(Nc1cc(Br)cnc1O)c1ccc(C(F)(F)F)cc1>>COC(=O)[C@H](Cc1ccccc1)n1cc(Br)cc(NC(=O)c2ccc(C(F)(F)F)cc2)c1=O,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US06187582B1,CC(N)c1ccc(Cl)cc1.CCOC(=O)CCl>>CC(NC(=O)CCl)c1ccc(Cl)cc1,,COC(C)(C)C,,,,test
US20110166103A1,Cc1cc(N(C(=O)OC(C)(C)C)c2ccc(C#N)cc2)ccc1Br.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N(c1ccc(C#N)cc1)c1ccc(Br)c(CBr)c1,,ClC(Cl)(Cl)Cl,,,,test
US20160024055A1,CC(C)(C)OC(=O)N1C[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C[C@H]1C(=O)O.N[C@@H]1CCCc2ccccc21>>CC(C)(C)OC(=O)N1C[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C[C@H]1C(=O)N[C@@H]1CCCc2ccccc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100272680A1,COC(=O)c1cn2cc(I)cc(C(F)(F)F)c2n1.O=C1CCC(=O)N1Br>>COC(=O)c1nc2c(C(F)(F)F)cc(I)cn2c1Br,,CN(C)C=O,O,,,test
US20050119246A1,CCC(CC)CBr.Cc1nn(CCNC(=O)OC(C)(C)C)c(C)c1O>>CCC(CC)COc1c(C)nn(CCNC(=O)OC(C)(C)C)c1C,,CN(C)C=O,O,,,test
US05686424,CC1C(C(=O)CCl)CC2CC1C2(C)C.CC1C(C(=O)O)CC2CC1C2(C)C.CC[C@H](C)[C@H](N)C(=O)NCc1ccccc1.O=C(O)[C@@H]1CCCN1>>CC1C(C(=O)CN2CCC[C@H]2C(=O)C2(C[NH-])C=CC=CC2)CC2CC1C2(C)C.CC[C@H](C)[C@H](N)C(=O)O,,C1CCOC1,,CCN(CC)CC,,test
US04428959,CCCCCCCCCCCCC(C#N)C(=O)C(=O)OCC.CS(=O)(=O)O>>CCCCCCCCCCCCC1=C(O)C(=O)NC1=O,,CS(=O)(=O)O,,CCO,O,test
US04897409,CC(O)C1CO1.Nc1ccc(OCc2cccc(Cl)c2)cc1>>CC(O)C(O)CNc1ccc(OCc2cccc(Cl)c2)cc1,,CC(C)O,,,,test
US20160168122A1,O=Cc1c(Cl)cccc1Br.O=c1[nH]ccc2cc(C3CC3)cc(F)c12>>O=Cc1c(Cl)cccc1-n1ccc2cc(C3CC3)cc(F)c2c1=O,[Cu]I,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US03933833,Cc1ccc(N=C=S)c(C)c1.NCCCO>>Cc1ccc(NC(=S)NCCCO)c(C)c1,,c1ccccc1,,,,test
US05731315,CC(C)(C)OC(=O)N[C@H]1CCN(Cc2cccc(C#N)c2)C1=O.Cl>>Cl.N#Cc1cccc(CN2CC[C@H](N)C2=O)c1,,CCOC(C)=O,,,,test
US20080076813A1,CC1(C)CC(=O)CC(=O)C1.COc1cc(CNO)cc(OC)c1OC>>COc1cc(CN(O)C2=CC(=O)CC(C)(C)C2)cc(OC)c1OC,,Cc1ccccc1,,,,test
US20120165318A1,CCCCOC(=O)c1ccc2nc(-c3ccc(F)cc3)c(N3CCCCCC3)nc2c1>>O=C(O)c1ccc2nc(-c3ccc(F)cc3)c(N3CCCCCC3)nc2c1,,O,,CO,[Na+].[OH-],test
US05859007,CC(C)N(C(=O)CN1C(=O)C(Cc2nn(C(=O)OC(C)(C)C)c3ccccc23)C(=O)N(c2ccccc2)c2ccccc21)c1ccc2c(c1)OCO2>>CC(C)N(C(=O)CN1C(=O)C(Cc2n[nH]c3ccccc23)C(=O)N(c2ccccc2)c2ccccc21)c1ccc2c(c1)OCO2,,C1COCCO1,,CCOCC,Cl,test
US20040023974A1,CC(=O)N[C@@H](Cc1ccccc1)C(=O)O.CCCCCNC(=O)[C@@H](N)Cc1ccc(N2CC(=O)N(Cc3ccc(OC)cc3)S2(=O)=O)cc1>>CCCCCNC(=O)[C@H](Cc1ccc(N2CC(=O)N(Cc3ccc(OC)cc3)S2(=O)=O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(C)=O,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US04725689,NO.O=Cc1nc(C(Cl)Cl)cnc1N1C(=O)c2ccccc2C1=O>>O=C1c2ccccc2C(=O)N1C1N=CC(C(Cl)Cl)=NC1=NO,,CS(C)=O,,Cl,O,test
US20110144056A1,CSc1ccc(-c2ccnn2C2CCCCO2)nn1>>CSc1ccc(-c2cc[nH]n2)nn1,,ClCCl,,C1COCCO1,Cl,test
US20140011795A1,NC(=O)c1cnn2cccc2c1Cl.N[C@H]1CC[C@H](O)CC1>>NC(=O)c1cnn2cccc2c1NC1CCC(O)CC1,,CN1CCCC1=O,CO,,,test
US05403931,C=C1CC2(CCN(C)CC2)O[C@H]1C.CCO.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>C=C1CC2(CCN(C)CC2)O[C@H]1C.O.O=C(O)[C@H](O)[C@@H](O)C(=O)O,,CCO,,,,test
US20090023723A1,COc1cccc(Nc2cnc(NC3CC3)nc2Nc2cccc(OC)c2)c1.O=C(n1ccnc1)n1ccnc1>>COc1cccc(-n2c(=O)n(-c3cccc(OC)c3)c3nc(NC4CC4)ncc32)c1,,ClCCl,,,,test
US20110101854A1,Cc1cccc(C)c1N.O=C(Cl)c1cccc(Br)c1>>Cc1cccc(C)c1NC(=O)c1cccc(Br)c1,,ClC(Cl)Cl,,C1CCOC1,CCN(CC)CC,test
US04284755,NCCCNC1CCCCC1.O=C(O)/C=C\C(=O)OC1CCCCC1>>O=C(O)C[C@H](NCCCNC1CCCCC1)C(=O)OC1CCCCC1,,C1COCCO1,,CCN(CC)CC,,test
US04472316,CC(O)=S.O=C(O)C=CC(=O)c1ccc(Oc2ccccc2)cc1>>CC(=O)SC(CC(=O)c1ccc(Oc2ccccc2)cc1)C(=O)O,,CCOCC,,,,test
US20100160303A1,NC(=O)c1ccc(-c2ccccc2F)c2c3c([nH]c12)CCCC3>>NC(=O)c1ccc(-c2ccccc2F)c2c1[nH]c1ccccc12,,Cc1ccccc1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20110251190A1,O=C1NC2(CC1(F)F)c1cc(O)ccc1Oc1ncc(Br)cc12.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>O=C1NC2(CC1(F)F)c1cc(OS(=O)(=O)C(F)(F)F)ccc1Oc1ncc(Br)cc12,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US05543534,CC1(C)CCCc2cc(Br)ccc21.O=C1CCC(=O)N1Br>>CC1(C)CCC(Br)c2cc(Br)ccc21,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20040220238A1,CC(C)(C)OC(=O)N1CC(=O)C[C@H]1C(=O)O.CCON>>CCON=C1C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1,,CCO,,Cl,c1ccncc1,test
US20150361059A1,CC(C)(C)OC(=O)N[C@@H](COc1c(N)cccc1F)C(=O)O>>CC(C)(C)OC(=O)N[C@H]1COc2c(F)cccc2NC1=O,,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,,test
US20060111375A1,COc1cc2nccc(Oc3ccc(C)nc3I)c2cc1OC.N#Cc1cccc(B(O)O)c1>>COc1cc2nccc(Oc3ccc(C)nc3-c3cccc(C#N)c3)c2cc1OC,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100311777A1,COC(=O)Cc1cc(C2CC2)c(C)cc1C>>Cc1cc(C)c(C2CC2)cc1CC(=O)O,,CO,,[Na+].[OH-],,test
US20090298823A1,CC(C)(C)OC(=O)NCc1cccc([N+](=O)[O-])c1.Cc1ccc(S(=O)(=O)n2ccc3c(Cl)nc(Cl)nc32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(Nc4cccc(CNC(=O)OC(C)(C)C)c4)nc(Cl)nc32)cc1,,CCCCO,,CCOC(C)=O,O,test
US20040214817A1,CO.O=C(O)c1ccc(F)cc1Cl>>COC(=O)c1ccc(F)cc1Cl,,CO,,C[Si](C)(C)Cl,,test
US20030186847A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(=O)O>>CC(C)(C)OC(=O)N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(=O)O,,CS(C)=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20150031689A1,CC(=O)OC(C)=O.Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(NC4CCNCC4)ncnc32)cc1>>CC(=O)N1CCC(Nc2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1,,c1ccncc1,,,,test
US20140296283A1,Cn1cc2cccc(C#N)c2n1>>Cn1cc2cccc(CN)c2n1,[Ni],CO,N,,,test
US20030166932A1,CCOC(=O)c1ccc(N(C)c2ccc3c(c2)C(C)(C)CC=C3C)cc1>>CC1=CCC(C)(C)c2cc(N(C)c3ccc(C(=O)O)cc3)ccc21,,CCO,,[K+].[OH-],,test
US09334273B1,CC(C)[Si](Cl)(O[Si](Cl)(C(C)C)C(C)C)C(C)C.OC[C@H]1C=C[C@H](O)[C@@H]1O>>CC(C)[Si]1(C(C)C)OC[C@H]2C=C[C@H](O)[C@@H]2O[Si](C(C)C)(C(C)C)O1,,CN(C)C=O,,c1c[nH]cn1,,test
US06166006,CCN1CCCCCCC1.Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CCl)cc2)CC3)cc1>>CC[N+]1(Cc2ccc(NC(=O)C3=Cc4cc(-c5ccc(C)cc5)ccc4CC3)cc2)CCCCCCC1.[Cl-],,CN(C)C=O,,CCOC(C)=O,,test
US20060199817A1,Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(Cl)nncc2c1.OB(O)c1ccc(C(F)(F)F)cc1C(F)(F)F>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(-c3ccc(C(F)(F)F)cc3C(F)(F)F)nncc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O,O=C([O-])[O-].[K+].[K+],test
US20070015757A1,COC(=O)c1ccc(CSc2ccccc2)cc1.O=C(OO)c1cccc(Cl)c1>>COC(=O)c1ccc(CS(=O)c2ccccc2)cc1,,ClCCl,,,,test
US20100272678A1,CI.O=c1[nH]nnc2c1[se]c1ccccc12>>Cn1nnc2c([se]c3ccccc32)c1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120208796A1,CN.O=[N+]([O-])c1ccc(F)cc1S(=O)(=O)Cl>>CNS(=O)(=O)c1cc(F)ccc1[N+](=O)[O-],,ClCCl,,C1CCOC1,,test
US05202356,CCN(CC)CC.O=C(Cl)C(=O)Cl.OCc1cc(Cl)nc(Cl)c1>>O=C[C@@H]1C[C@H]1c1cc(Cl)nc(Cl)c1,,CCN(CC)CC,,CS(C)=O,,test
US20100063081A1,CC(C)(C)OC(=O)N1CCC(CCCC(=O)c2ccc(SCF)cc2)CC1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)OC(=O)N1CCC(CCCC(O)c2ccc(S(=O)CF)cc2)CC1,,ClCCl,,,,test
US20140088094A1,Cc1cc2c(cc1[N+](=O)[O-])N(S(=O)(=O)c1ccc(F)cc1)CCC2>>Cc1cc2c(cc1N)N(S(=O)(=O)c1ccc(F)cc1)CCC2,[Pd],CCO,,,,test
US20060194857A1,Cc1ccc(C(=O)Cl)cc1.O=S(=O)(c1ccccc1)n1cccc1>>Cc1ccc(C(=O)c2ccn(S(=O)(=O)c3ccccc3)c2)cc1,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20060173180A1,O=C1C(=Nc2cccc(C(F)(F)F)c2)c2ccccc2N1c1ccccc1OCc1ccccc1>>O=C1C(=Nc2cccc(C(F)(F)F)c2)c2ccccc2N1c1ccccc1O,[Pd],CO,,O=C[O-].[NH4+],,test
US20090312309A1,Cl.FC(F)(F)c1ccc(-c2ccc(Cl)nn2)cc1.NC1CCCNC1>>Cl.NC1CCCN(c2ccc(-c3ccc(C(F)(F)F)cc3)nn2)C1,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20090131467A1,NN.O=C(Cc1cccc(OC(F)(F)F)c1)c1c(O)c2cccnc2n(-c2cccc(OC(F)(F)F)c2)c1=O>>O=c1c2c(Cc3cccc(OC(F)(F)F)c3)n[nH]c2c2cccnc2n1-c1cccc(OC(F)(F)F)c1,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US06057369,CC(C)(C)OC(=O)C=CCc1ccccc1>>O=C(O)C=CCc1ccccc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20150094297A1,CO.Fc1cc(OCc2ccccc2)c2cc(-c3cn4nc(Br)sc4n3)oc2c1>>COc1nn2cc(-c3cc4c(OCc5ccccc5)cc(F)cc4o3)nc2s1,,CO,ClCCl,C[O-].[Na+],,test
US20140005133A1,NC(=O)CCC(=O)NCl.ON=Cc1ccccn1>>N=C(Cl)c1ccccn1,,CN(C)C=O,,,,test
US03971773,C[C@]12C=CC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1C[C@@H](O)[C@]2(O)C(=O)CCl.[N-]=[N+]=CCOC1CCCCO1>>C[C@]12C=CC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1C[C@@H](OCCOC1CCCCO1)[C@]2(O)C(=O)CCl,,CCOCC,CO,,,test
US20020147198A1,Nc1ccc(Cl)cc1.Nc1cccnc1C(=O)O>>Nc1cccnc1C(=O)Nc1ccc(Cl)cc1,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20050222142A1,OC[C@H]1O[C@@H]1c1cccc(F)c1.c1ccc2c(c1)CCN2>>OC[C@@H](O)[C@H](c1cccc(F)c1)N1CCc2ccccc21,,CCOC(C)=O,,,,test
US05646149,CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O.O=C(O)CC(=O)O>>C=C(C(=O)O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1,,Cc1ccccc1,O,C1CCNCC1,CC(=O)O,test
US20120196884A1,Cc1ccc(N=C=O)cc1[N+](=O)[O-].Nc1ccccc1>>Cc1ccc(NC(=O)Nc2ccccc2)cc1[N+](=O)[O-],,CCOC(C)=O,,,,test
US20060276533A1,c1ncn(C2CCC3(CC2)OCCO3)n1>>O=C1CCC(n2cncn2)CC1,,C1CCOC1,Cl,,,test
US20020016506A1,CC(=O)OC(C)=O.Nc1ccccc1[N+](=O)[O-]>>CC(=O)Nc1ccccc1[N+](=O)[O-],,C1CCOC1,,O,[H-].[Na+],test
US20110230458A1,CCCCc1nnc(C(=O)NC[C@H]2CCCN2CC)cc1-c1ccc(OC2CCCCC2)cc1.Cl.ClCCl>>CCCCc1nnc(C(=O)NC[C@H]2CCCN2CC)cc1-c1ccc(OC2CCCCC2)cc1.Cl.Cl,,C1COCCO1,ClCCl,,,test
US20100197680A1,COC(=O)c1ccc(CCC(/C=C/c2cc(F)ccc2OCCCN2CCCC2=O)CCc2ccc(C(=O)OC)cc2)cc1>>O=C(O)c1ccc(CCC(/C=C/c2cc(F)ccc2OCCCN2CCCC2=O)CCc2ccc(C(=O)O)cc2)cc1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US05417882,N#Cc1ccc(-c2ccc(OCCCCCC(=O)O)cc2)cc1.O=S(Cl)Cl>>N#Cc1ccc(-c2ccc(OCCCCCC(=O)Cl)cc2)cc1,CN(C)C=O,Cc1ccccc1,,,,test
US20040242596A1,CC(C)(C)OC(=O)NCCC=O.CCC(N)c1nc2onc(C(F)(F)F)c2c(=O)n1Cc1ccccc1>>CCC(NCCCNC(=O)OC(C)(C)C)c1nc2onc(C(F)(F)F)c2c(=O)n1Cc1ccccc1,,CO,,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20020137968A1,CC(=O)c1ccc(C(=O)O)cc1.CC(C)(C)CCN.CCN(CC)CC>>CC(=O)c1ccc(C(=O)NCC2CCCC2(C)C)cc1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US20120114739A1,C[C@@H](O)c1nnc(N2CCC(c3cc(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)n4ncc(-c5ccc(-c6ccccc6)nc5)c4n3)CC2)o1.O=C1CCC(=O)N1Br>>C[C@@H](O)c1nnc(N2CCC(c3nc4c(-c5ccc(-c6ccccc6)nc5)cnn4c(N(COCC[Si](C)(C)C)COCC[Si](C)(C)C)c3Br)CC2)o1,,CC#N,,,,test
US20070243568A1,Nc1nc(OCc2ccc(CNC(=O)C(F)(F)F)cc2)c2nc(CCC(N)C(=O)CCCCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@@H]43)[nH]c2n1>>NCc1ccc(COc2nc(N)nc3[nH]c(CCC(N)C(=O)CCCCCNC(=O)CCCC[C@@H]4SC[C@@H]5NC(=O)N[C@@H]54)nc23)cc1,,CO,,CN,,test
US05910495,COc1ccc(C(=O)Nc2ccccc2Nc2ccccc2)cc1>>COc1ccc(CNc2ccccc2Nc2ccccc2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20160130268A1,CO.COc1cc(CC(=O)O)c(Cl)c(OC)c1>>COC(=O)Cc1cc(OC)cc(OC)c1Cl,,CCOC(C)=O,,O=S(Cl)Cl,,test
US20040122047A1,CCO.O=C(O)CC(c1ccncc1)c1ccc2c(c1)CNCC2>>CCOC(=O)CC(c1ccncc1)c1ccc2c(c1)CNCC2,Cl,,,O=C([O-])O.[Na+],,test
US20110070192A1,Cc1ccc(S(=O)(=O)O[C@@H]2CO[C@@H]3COC(c4ccccc4)O[C@H]3C2)cc1.O=c1cc[nH]c(=O)[nH]1>>O=c1ccn([C@H]2CO[C@@H]3COC(c4ccccc4)O[C@H]3C2)c(=O)[nH]1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20110212918A1,CC(=O)OC(C)=O.Cc1cc(N)cnc1SCc1ccccc1>>CC(=O)Nc1cnc(SCc2ccccc2)c(C)c1,,C1CCOC1,,CCN(CC)CC,,test
US20130131040A1,N#Cc1ncc(Cl)nc1Cl.NC(=O)[C@H](N)Cc1ccccc1>>N#Cc1ncc(N[C@H](Cc2ccccc2)C(N)=O)nc1Cl,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,O,test
US20120276018A1,O=C(CCl)c1cccs1.O=C(N[C@H]1CN2CCC1CC2)OC(c1ccc(Cl)cc1)c1ccccc1Cl>>O=C(N[C@H]1C[N+]2(CC(=O)c3cccs3)CCC1CC2)OC(c1ccc(Cl)cc1)c1ccccc1Cl.[Cl-],,CCOC(C)=O,,,,test
US20100203007A1,COC(=O)CCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1.OCc1cc(O)cc(CO)c1>>COC(=O)CCOCCOCCOCCOc1cc(CO)cc(CO)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20010051620A1,COc1cc(COC(C)=O)c(COC(C)=O)cc1OCCCl>>COc1cc(CO)c(CO)cc1OCCCl,,CO,,N,,test
US20030027840A1,C1COCCO1.C=CCC1CC2(CCCC)Cc3cc(OCOC)ccc3C2=C(C)C1=O.O>>CCCCC12Cc3cc(OCOC)ccc3C1=C(C)C(=O)C(CC(=O)CO)C2,,O,,,,test
US20070004772A1,COc1nc(C(F)(F)F)ccc1Cn1nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)ccn2c1=O>>O=c1n(Cc2ccc(C(F)(F)F)nc2O)nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)ccn12,,Br,,,,test
US20110212102A1,C=CC#N.Cc1c(C(N)=O)sc2ncnc(Nc3ccc(F)cc3O[C@@H]3CCCNC3)c12>>Cc1c(C(N)=O)sc2ncnc(Nc3ccc(F)cc3O[C@@H]3CCCN(CCC#N)C3)c12,,CCOC(C)=O,CO,CCN(CC)CC,CN(C)C=O,test
US04431822,CC(C)Oc1cc(N)c(F)cc1Br.O=C1OC(=O)C2=C1CCCC2>>CC(C)Oc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Br,,CC(=O)O,,O,,test
US20110281845A1,C=CC[C@H](N)C(=O)N1[C@@H](CC=C)CC[C@H]1C(=O)NCCc1ccccc1.C[C@@H](C(=O)O)N(C)C(=O)OC(C)(C)C>>C=CC[C@H](NC(=O)[C@H](C)N(C)C)C(=O)N1[C@@H](CC=C)CC[C@H]1C(=O)NCCc1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US04156017,C#CCBr.CNCc1ccc(Cl)cc1>>C#CCN(C)Cc1ccc(Cl)cc1,,c1ccccc1,,CCN(CC)CC,,test
US06339096B1,CN(C)Cc1ccc(SC2CCNCC2)cc1.O=C(Cl)OCc1ccccc1>>CN(C)Cc1ccc(SC2CCN(C(=O)OCc3ccccc3)CC2)cc1,,C1CCOC1,CCOCC,O,[Na+].[OH-],test
US20120022045A1,CC(C)(C)OC(=O)NC1(C(N)=NO)CCC(CO[Si](C)(C)C(C)(C)C)CC1.COC(=O)C#CC(=O)OC>>COC(=O)C=C(ON=C(N)C1(NC(=O)OC(C)(C)C)CCC(CO[Si](C)(C)C(C)(C)C)CC1)C(=O)OC,,CO,,,,test
US06399603B1,CC(C)(C)C(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.CO.O=Cc1cc([N+](=O)[O-])cc2c(O)nc(Nc3ccc(Cl)c(Cl)c3)nc12>>O=C(O)C=Cc1cc([N+](=O)[O-])cc2c(O)nc(Nc3ccc(Cl)c(Cl)c3)nc12,,C1CCOC1,ClCCl,,,test
US20100331326A1,COC(=O)c1ccc(N2CCN(c3cnccc3C)C2=O)cc1F.NN>>Cc1ccncc1N1CCN(c2ccc3c(=O)[nH][nH]c3c2)C1=O,,ClC(Cl)Cl,,CO,O,test
US20160214956A1,CCOP(OCC)OCC.COc1ccc(CBr)c(C)c1>>CCOP(=O)(Cc1ccc(OC)cc1C)OCC,,C1COCCO1,,,,test
US20090247618A1,O=[N+]([O-])c1cccc(S(=O)(=O)OC[C@H]2CO2)c1.Oc1cc(Cl)ccc1OCc1ccccc1>>Clc1ccc(OCc2ccccc2)c(OC[C@H]2CO2)c1,,CCCCCCC,ClCCl,CN(C)C=O,O,test
US20100216746A1,N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CN)c2F)c1.O=C(O)c1cc[nH]n1>>N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CNC(=O)c3cc[nH]n3)c2F)c1,,CN(C)C=O,CO,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120184542A1,NCc1cccc(F)c1.Nc1cc(C(=O)On2nnc3ccccc32)ccc1Cl>>Nc1cc(C(=O)NCc2cccc(F)c2)ccc1Cl,,ClCCl,,CCN(CC)CC,CN(C)C=O,test
US20110105475A1,CCOC(=O)c1cc2c(C)c(N3CCN(C(=O)OC(C)(C)C)CC3)ccc2o1.O=C(O)C(F)(F)F>>CCOC(=O)c1cc2c(C)c(N3CCNCC3)ccc2o1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20090099184A1,O=C(NCc1ccc(Cl)cc1Cl)c1ccc(F)nc1.OCCN1CCOCC1>>O=C(NCc1ccc(Cl)cc1Cl)c1ccc(OCCN2CCOCC2)nc1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20140228579A1,NCc1ccccc1.O=C(Cl)c1cccs1>>O=C(NCc1ccccc1)c1cccs1,,ClCCl,,,,test
US20120283288A1,CCOC(=O)Nc1c(Oc2ccc(N)c(F)c2)ccnc1N.CI>>CCOC(=O)N(C)c1c(Oc2ccc(N)c(F)c2)ccnc1N,,C1CCOC1,,[H-].[Na+],,test
US20040236109A1,CC(=O)N1c2ccc(N)cc2C(C)(c2ccccc2)CC1(C)C.O=C(Cl)CBr>>CC(=O)N1c2ccc(NC(=O)CBr)cc2C(C)(c2ccccc2)CC1(C)C,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20080255197A1,Cc1cnc(C=O)c(C)c1.NC1CCCc2cccnc21>>Cc1cnc(CNC2CCCc3cccnc32)c(C)c1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20160009666A1,Nc1nc(Nc2cc(Cl)cc(Cl)c2)n[nH]1.O=Cc1ccccc1>>Clc1cc(Cl)cc(Nc2n[nH]c(NCc3ccccc3)n2)c1,,CO,,[BH4-].[Na+],,test
US20070142380A1,O=C(O)c1cc2cc([N+](=O)[O-])ccc2[nH]1>>Nc1ccc2[nH]ccc2c1,,CN(C)C=O,,O,[H-].[Na+],test
US20120296074A1,CCCCCCCCCCCCCCCCCCOc1cc(CN=[N+]=[N-])cc(OCCCCCCCCCCCCCCCCCC)c1OCCCCCCCCCCCCCCCCCC>>CCCCCCCCCCCCCCCCCCOc1cc(CN)cc(OCCCCCCCCCCCCCCCCCC)c1OCCCCCCCCCCCCCCCCCC,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100041719A1,CC(C)(C)OC(=O)NCCC(=O)O.[Li]c1ccccc1>>CC(C)(C)OC(=O)NCCC(=O)c1ccccc1,,C1CCOC1,,,,test
US04987132,COC(=O)C=CC(C)(C)c1ccccc1>>COC(=O)CCC(C)(C)c1ccccc1,,CO,,Cl,[Mg],test
US20120309746A1,Nc1ccc(I)cn1.O=C1CCC(=O)N1Br>>Nc1ncc(I)cc1Br,,CC#N,,,,test
US20020022628A1,CS(=O)(=O)Cl.Fc1ccc(N2CCNCC2)cc1>>CS(=O)(=O)N1CCN(c2ccc(F)cc2)CC1,,ClCCl,,c1ccncc1,,test
US20130109682A1,CCOC(C)=O.O=C1C=COC(c2ccncc2[N+](=O)[O-])(C(F)(F)F)C1>>CC(=O)OC1C=COC(c2ccncc2[N+](=O)[O-])(C(F)(F)F)C1,,CCO,,O,[BH4-].[Na+],test
US20120225866A1,CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCNc3ccncc3[N+](=O)[O-])ccc21>>CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCNc3ccncc3N)ccc21,[Pd],CO,,,,test
US04283408,COC(=N)CCSCc1csc(NC(=N)N)n1.Nc1ccc(S(N)(=O)=O)cc1>>N=C(N)Nc1nc(CSCCC(=N)NS(=O)(=O)c2ccc(N)cc2)cs1,,CCO,,,,test
US20150038523A1,CC(C)(C)OC(=O)N1CCCN(C(=O)OC(C)(C)C)C1=Nc1cccc(C(=O)NCC(=O)OCc2ccccc2)c1>>CC(C)(C)OC(=O)N1CCCN(C(=O)OC(C)(C)C)C1=Nc1cccc(C(=O)NCC(=O)O)c1,[Pd],CCO,,,,test
US04849419,O=C(Sc1c(F)c(F)c(F)c(F)c1F)c1cccc(O)c1.S=C(Cl)Cl>>O=C(Sc1c(F)c(F)c(F)c(F)c1F)c1cccc(OC(=S)Cl)c1,,ClC(Cl)Cl,O,[Na+].[OH-],,test
US20150307454A1,N#Cc1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2ncc3ccccc3c2C(F)(F)F)cc1.NO>>NC(=NO)c1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2ncc3ccccc3c2C(F)(F)F)cc1,,CCO,,CCN(CC)CC,Cl,test
US05665732,CC(=O)c1ccc(F)cc1N.O=N[O-]>>Cc1n[nH]c2cc(F)ccc12,,O,,Cl,,test
US20070254867A1,COC(CN)OC.O=Cc1cc(Br)ccc1F>>COC(CN=Cc1cc(Br)ccc1F)OC,,Cc1ccccc1,,,,test
US20060178381A1,CC(C)(C)OC(=O)N1Cc2cc(Cl)c(N3CCCC3)cc2C1.Cl>>Cl.Clc1cc2c(cc1N1CCCC1)CNC2,,C1COCCO1,,,,test
US20100317659A1,CCOC(=O)C(=O)Nc1c(C)cccc1C(N)=O>>CCOC(=O)c1nc(O)c2cccc(C)c2n1,,ClCCCl,,C[Si](C)(C)Cl,,test
US20110118236A1,CC(NC(=O)Cn1nc(C(F)(F)F)c2c1CN(C(=O)OC(C)(C)C)CC2)c1ccc(Cl)cc1>>CC(NC(=O)Cn1nc(C(F)(F)F)c2c1CNCC2)c1ccc(Cl)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160168096A1,O=C1CCCC1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>O=S(=O)(OC1=CCCC1)C(F)(F)F,,C1CCOC1,,[Cl-].[NH4+],C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20030055086A1,COC(=O)C(Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)NC(=O)C(CSC(C)=O)C1CCc2cc(Br)ccc21>>O=C(N[C@@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)C(=O)O)C(CS)C1CCc2cc(Br)ccc21,,CO,,Cl,[Na+].[OH-],test
US04812164,CC(C)O.CC(C)Oc1cc(-n2c(Cl)nc(C(F)(F)C(F)(F)F)cc2=O)c(F)cc1Cl>>CC(C)Oc1cc(-n2c(OC(C)C)nc(C(F)(F)C(F)(F)F)cc2=O)c(F)cc1Cl,,CC(C)O,,[Na],,test
US20150031674A1,CC(C)(C)OC(=O)N1CCC(Cn2c(=O)c(Br)cc3cnc(S(C)(=O)=O)nc32)CC1.CCN>>CCNc1ncc2cc(Br)c(=O)n(CC3CCN(C(=O)OC(C)(C)C)CC3)c2n1,,CC(C)O,,CCN(C(C)C)C(C)C,Cl,test
US20100317704A1,O=C(CBr)Nc1cccc(C(F)(F)F)c1.O=C1NC2(CCOC2)N=C1c1ccc(-c2ccccn2)cc1>>O=C(CN1C(=O)C(c2ccc(-c3ccccn3)cc2)=NC12CCOC2)Nc1cccc(C(F)(F)F)c1,,CN(C)C=O,CO,[H-].[Na+],,test
US20150158847A1,COc1ccc(Br)cn1.O=CC1CC1>>COc1ccc(C(O)C2CC2)cn1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20150210682A1,CCCOc1ccc(CCNC(=O)OC(C)(C)C)cc1OCCC>>CCCOc1ccc(CCN)cc1OCCC,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20070010542A1,COC(OC)OC.OCC(CO)CO>>COC1OCC(CO)CO1,,CCN(CC)CC,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100311966A1,CCOC(=O)c1sc(N2CC[C@H](NC(=O)c3nc(Cl)c(CC)[nH]3)C2)nc1C>>CCc1[nH]c(C(=O)N[C@H]2CCN(c3nc(C)c(C(=O)O)s3)C2)nc1Cl,,CO,,O,[Li+].[OH-],test
US05173484,CNCC1(O)CCN(Cc2ccccc2)C1.[Cl-].[Cl-]>>CNCC1(O)CCNC1.Cl.Cl,[Pd],CO,,,,test
US20040043987A1,COc1ccccc1B(O)O.O=S1(=O)NC(C2CCCCC2)=Nc2c(Cl)ccc(I)c21>>COc1ccccc1-c1ccc(Cl)c2c1S(=O)(=O)NC(C1CCCCC1)=N2,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20130331419A1,COC(OC)N(C)C.Cc1c([N+](=O)[O-])cc(F)cc1[N+](=O)[O-]>>CN(C)C=Cc1c([N+](=O)[O-])cc(F)cc1[N+](=O)[O-],,CN(C)C=O,,,,test
US20060270654A1,C#C[Si](C)(C)C.COc1cc(Br)ccc1Cl>>COc1cc(C#C[Si](C)(C)C)ccc1Cl,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,,CCN(CC)CC,,test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n(C2CCC(N3CCOCC3)CC2)c2ncnn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(C2CCC(N3CCOCC3)CC2)c2ncnn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20100144739A1,COC(CCl)(OC)OC.NNc1ccc(Nc2cccc(Cl)c2)nn1>>ClCc1nnc2ccc(Nc3cccc(Cl)c3)nn12,,CCOCC,Cl,,,test
US20130131279A1,COc1cc(C=O)ccc1OCCN1CCNC1=O.NO>>COc1cc(C=NO)ccc1OCCN1CCNC1=O,,CCO,,,,test
US20110212946A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.N#CCc1ccccc1>>CC(C)(C)OC(=O)N1CCC(O)(C(C#N)c2ccccc2)CC1,,C1CCOC1,,[Li]CCCC,,test
US20040053908A1,N#Cc1cc2c(Oc3ccc(N)c(F)c3)ccnc2cc1OCc1ccccc1.O=C=Nc1ccccc1>>N#Cc1cc2c(Oc3ccc(NC(=O)Nc4ccccc4)c(F)c3)ccnc2cc1OCc1ccccc1,,CC#N,,Cc1ccccc1,,test
US20060241296A1,FC(F)(F)c1ccc(-c2cc(Cl)nc(Cl)n2)cc1.Nc1ccc2c(c1)CC(O)C2>>OC1Cc2ccc(Nc3cc(-c4ccc(C(F)(F)F)cc4)nc(Cl)n3)cc2C1,,CCOC(C)=O,CS(C)=O,,,test
US20150291655A1,C=CC[Mg]Br.CCC(=O)CC>>C=CCC(O)(CC)CC,,C1CCOC1,,,,test
US20130085144A1,N#Cc1nc(SCc2cc(F)cc(F)c2)ccc1N.O=N[O-]>>Nc1n[nH]c2ccc(SCc3cc(F)cc(F)c3)nc12,,Cl,O,Cl[Sn]Cl,,test
US20120220795A1,CCOC(=O)C(F)(F)Br.O=[N+]([O-])c1ccc(I)cc1>>CCOC(=O)C(F)(F)c1ccc([N+](=O)[O-])cc1,[Cu],CS(C)=O,,,,test
US20060116400A1,O=C1CCC(=O)O1.O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(-c2ccc(C3=NOC(CO)C3)nc2)c(F)c1>>O=C(O)CCC(=O)OCC1CC(c2ccc(-c3ccc(N4C[C@H](Cn5ccnn5)OC4=O)cc3F)cn2)=NO1,CN(C)c1ccncc1,CN(C)C=O,,c1ccncc1,,test
US20110269783A1,Nn1c(N2CCCC2)nc2cc(F)ccc2c1=O.O=C(O)CCc1cccc(F)c1>>O=C(CCc1cccc(F)c1)Nn1c(N2CCCC2)nc2cc(F)ccc2c1=O,,ClCCl,,O=C(Cl)C(=O)Cl,c1ccncc1,test
US20100216781A1,CCOC(=O)CNc1ncc(Br)nc1NCCC1CCOCC1.O=C1CNc2ncc(Br)nc2N1CCC1CCOCC1>>O=C1CNc2ncc(-c3cnc4[nH]ccc4c3)nc2N1CCC1CCOCC1,,CCO,,Cl,,test
US05118686,CCCOc1ccccc1-c1nc(O)cc(C(=O)OCC)n1.CN>>CCCOc1ccccc1-c1nc(O)cc(C(=O)NC)n1,,CCO,,,,test
US20090227588A1,COC(=O)c1cccc(-c2ccc(F)nc2)c1>>O=C(O)c1cccc(-c2ccc(F)nc2)c1,,C1COCCO1,O,[Li+].[OH-],,test
US20100010053A1,CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.N#Cc1ccc(F)c2c(C=O)c[nH]c12>>CCOC(=O)/C=C/c1c[nH]c2c(C#N)ccc(F)c12,,CC#N,,,,test
US20150203486A1,Brc1cnc(I)nc1.CCOC(=O)C1CCC(=O)CC1>>CCOC(=O)C1CCC(O)(c2ncc(Br)cn2)CC1,,Cc1ccccc1,,[Li]CCCC,,test
US20100197634A1,CC(=O)c1cc(Cl)c(Nc2nc3ccncc3c3c(=O)[nH]ccc23)c(Cl)c1.CCNO>>CCON=C(C)c1cc(Cl)c(Nc2nc3ccncc3c3c(=O)[nH]ccc23)c(Cl)c1,,CO,,Cl,CC(=O)[O-].[Na+],test
US20100216691A1,COCCOCCOCCOCCC(=O)OC(C)(C)C.O=C1CCC(=O)N1O>>COCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O,,ClCCl,O=C(O)C(F)(F)F,CCN=C=NCCCN(C)C,Cl,test
US20040082784A1,CC[C@@H](N)COC.O=[N+]([O-])c1c(Cl)ccnc1Cl>>CC[C@H](COC)Nc1nccc(Cl)c1[N+](=O)[O-],,CCO,,CCN(CC)CC,,test
US20090105211A1,CI.Cc1ccc(-c2nnn[nH]2)cc1NC(=O)c1ccc(Nc2nc(-c3ccccc3)c3ccccc3n2)cc1>>Cc1ccc(-c2nnn(C)n2)cc1NC(=O)c1ccc(Nc2nc(-c3ccccc3)c3ccccc3n2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150284384A1,CCOC(=O)C(C)(F)F.COP(C)(=O)OC>>COP(=O)(CC(=O)C(C)(F)F)OC,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20160083368A1,CC1(C)OB(c2cnn(C3CCOCC3)c2)OC1(C)C.Cn1nc(NS(C)(=O)=O)c2c(Cl)ccc(-c3ccc(Cl)nc3[C@H](Cc3cc(F)cc(F)c3)NC(=O)Cn3nc(C(F)(F)F)c4c3C(F)(F)[C@@H]3C[C@H]43)c21>>Cn1nc(NS(C)(=O)=O)c2c(Cl)ccc(-c3ccc(-c4cnn(C5CCOCC5)c4)nc3[C@H](Cc3cc(F)cc(F)c3)NC(=O)Cn3nc(C(F)(F)F)c4c3C(F)(F)[C@@H]3C[C@H]43)c21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20080115247A1,CC(C)(C)[NH3+].CS(=O)(=O)Oc1ccc(OCCc2ccc(CC(SCCc3ccc(O)cc3)C(=O)[O-])cc2)cc1>>CC(C)(C)[NH3+].CS(=O)(=O)Oc1ccc(OCCc2ccc(C[C@H](SCCc3ccc(O)cc3)C(=O)[O-])cc2)cc1,,CCO,,,,test
US20070259965A1,CC[C@H](N=[N+]=[N-])[C@H]1CN(C(=O)OC(C)(C)C)C(=O)O1>>CC[C@H](N=[N+]=[N-])[C@H](O)CNC(=O)OC(C)(C)C,,CO,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090298819A1,CCOC(=O)CBr.COc1ccc(O)c([N+](=O)[O-])c1>>CCOC(=O)COc1ccc(OC)cc1[N+](=O)[O-],,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US04282365,Cc1c(C(=O)O)ccc2c1C(Cl)c1ccccc1CO2.Sc1ccccc1>>COC(=O)c1ccc2c(c1)C(Sc1ccccc1)c1ccccc1CO2,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20140275085A1,CCn1cc(-c2cc(Oc3ccc(-c4cnc(NC(C)C)nc4OC)nc3C)ccn2)cn1>>CCn1cc(-c2cc(Oc3ccc(-c4cnc(NC(C)C)[nH]c4=O)nc3C)ccn2)cn1,,CC(=O)O,,Br,,test
US20100216810A1,N#Cc1c(Oc2ccc(F)c(NC(=O)Cc3cccc(C(F)(F)F)c3)c2)ccc2nc(N)sc12.O=C(Cl)C1CC1>>N#Cc1c(Oc2ccc(F)c(NC(=O)Cc3cccc(C(F)(F)F)c3)c2)ccc2nc(NC(=O)C3CC3)sc12,,CC(=O)N(C)C,,O,c1ccncc1,test
US20150299201A1,C1CCC2(C1)CCNCC2.Cc1nnc2n1-c1ccccc1C(c1ccc(Cl)cc1)=CC2CC(=O)O>>Cc1nnc2n1-c1ccccc1C(c1ccc(Cl)cc1)=CC2CC(=O)N1CCC2(CCCC2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150238601A1,Cc1cc2[nH]ncc2cc1N.Clc1ccnc(Cl)n1>>Cc1cc2[nH]ncc2cc1Nc1ccnc(Cl)n1,,CCO,,Cl,,test
US20100273786A1,FC(F)(F)c1ncc2cnccn12>>FC(F)(F)c1ncc2n1CCNC2,[Pd],CCO,,,,test
US05571806,CCCBr.O=C1Nc2ccccc2Sc2ccccc21>>CCCN1C(=O)c2ccccc2Sc2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20040058894A1,CCCCCCCCCC(O)c1ccc(CO)cc1C>>CCCCCCCCCC(=O)c1ccc(C=O)cc1C,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20120184520A1,CN(Cc1cccc(-c2ccc(C#N)cc2)c1)C(=O)CNC(=O)OC(C)(C)C>>CN(Cc1cccc(-c2ccc(CN)cc2)c1)C(=O)CNC(=O)OC(C)(C)C,[Ni],CO,,N,,test
US05965553,Cc1ncc[nH]1.N#CC[C@H]1O[C@H](c2cccc3ccccc23)c2cc(Cl)ccc2N(CCCCI)C1=O>>Cc1nccn1CCCCN1C(=O)[C@@H](CC#N)O[C@H](c2cccc3ccccc23)c2cc(Cl)ccc21,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20160176861A1,CC1(C)CC2(CCC1=O)OCCO2>>CC1(C)CC2(CCC1O)OCCO2,,CO,,[BH4-].[Na+],,test
US20070293548A1,CSc1cccc(CC(=O)CN=[N+]=[N-])c1.Cl[Sn]Cl>>CSc1cccc(CC(=O)CN)c1.Cl,,CCO,,,,test
US20140058021A1,CCCCCCCCN.COC(=O)CC(=O)OC>>CCCCCCCCNC(=O)CC(=O)OC,,CO,,,,test
US05922086,Nc1cccc2cccc(N)c12.O=CO>>C1=Nc2cccc3cccc(c23)N1,,O,,N,,test
US04709052,BrC1C=CCCCC1.CNC(=O)c1ccccc1>>CN(C(=O)c1ccccc1)C1C=CCCCC1,,CN(C)C=O,,O,[H-].[Na+],test
US05656629,CCc1nn(C2CCCC2)c(N)c1C(N)=O.COC(=O)Cc1ccc(OCc2nnn[nH]2)cc1>>CCc1[nH]n(C2CCCC2)c2nc(Cc3ccc(OCc4nnn[nH]4)cc3)nc(=O)c1-2,,CCO,,[Na],,test
US04133809,Cc1nnc2n1-c1ccc(Cl)cc1N(c1ccccc1)C(=O)C2CCN(C)Cc1ccccc1>>CNCCC1C(=O)N(c2ccccc2)c2cc(Cl)ccc2-n2c(C)nnc21,[Ni],CCO,,[H][H],,test
US20140243302A1,COS(=O)(=O)c1ccccc1.COc1ccc2ncc(F)c(CC(O)C34CCC(NC(=O)OC(C)(C)C)(CC3)CO4)c2n1>>COc1ccc2ncc(F)c(CC(OC)C34CCC(NC(=O)OC(C)(C)C)(CC3)CO4)c2n1,,CN(C)C=O,,[H-].[Na+],,test
US20030220324A1,O=[N+]([O-])c1ccccc1F.c1ccc(CN2CCNCC2)cc1>>O=[N+]([O-])c1ccccc1N1CCN(Cc2ccccc2)CC1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,CN(C)C=O,test
US04983592,CCCCCCCCCCCCCCc1cccc(OC)c1>>CCCCCCCCCCCCCCc1cccc(O)c1,,ClCCl,,BrB(Br)Br,O,test
US05281602,CCCCC(=N)N.CCOC(=O)C1CN(C(C)=O)CCC1=O>>CCCCc1nc2c(c(=O)[nH]1)CN(C(C)=O)CC2,,CCO,CO,Cl,C[O-].[Na+],test
US05432182,CCCC(=O)c1cnc2c(O)cccc2c1Nc1ccccc1C.COCCOS(=O)(=O)c1ccccc1>>CCCC(=O)c1cnc2c(OCCOC)cccc2c1Nc1ccccc1C,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20050153996A1,O=C(O)Cc1ccc(Br)cc1.OB(O)c1ccc(C(F)(F)F)cc1>>O=C(O)Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1,O,CC(C)O,O,O=C([O-])[O-].[Na+].[Na+],,test
US04085272,O=C(O)CCCCCCC1=CC(O)CC1=O.OCCS>>O=C(O)CCCCCCC1=CC(SCCO)CC1=O,,CO,,C[O-].[Na+],,test
US20150210655A1,CN(C)CCCl.O=c1[nH]c2cc(Br)ccc2o1>>CN(C)CCn1c(=O)oc2ccc(Br)cc21,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20060094754A1,CC(=O)CC(=O)C(F)(F)F.CC(C)(C)c1ccc(N)c(C(=O)c2ccccc2)c1>>Cc1nc2ccc(C(C)(C)C)cc2c(-c2ccccc2)c1C(=O)C(F)(F)F,,CCCCCCC,CCOC(C)=O,CC(C)O,,test
US20120065212A1,COC(=O)c1ncc(F)c(-c2ccc(Cl)cc2)n1.OCC(F)(F)F>>COC(=O)c1ncc(OCC(F)(F)F)c(-c2ccc(Cl)cc2)n1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20150232445A1,CCCOc1c(C2CCNCC2)ccc2c1CC[C@H](C)N2C(C)=O.COC(=O)Cl>>CCCOc1c(C2CCN(C(=O)OC)CC2)ccc2c1CC[C@H](C)N2C(C)=O,,ClCCl,,CCN(CC)CC,,test
US04057647,CC(O)(CCO)c1ccc(-c2ccc(F)cc2F)cc1>>CC(CCO)c1ccc(-c2ccc(F)cc2F)cc1,[Pd],CC(=O)O,,,,test
US20140021407A1,C[Si](C)(C)C(F)(F)F.O=C1CCC(C2CCC3(CC2)OCCO3)CC1>>OC1(C(F)(F)F)CCC(C2CCC3(CC2)OCCO3)CC1,,C1CCOC1,,Cl,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20090281092A1,CCOC(=O)C(F)(F)CNC(C)C.O=[N+]([O-])c1cnc(Cl)nc1Cl>>CCOC(=O)C(F)(F)CN(c1nc(Cl)ncc1[N+](=O)[O-])C(C)C,,CC(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20040038239A1,COc1cccc(C=O)c1.C[N+](=O)[O-]>>COc1cccc(C(O)C[N+](=O)[O-])c1,,CO,,CC(=O)O,[Na+].[OH-],test
US20030191189A1,C[C@H](CO)N1C(=O)c2ccccc2C1=O.Oc1cc(F)ccc1F>>C[C@H](COc1cc(F)ccc1F)N1C(=O)c2ccccc2C1=O,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160176861A1,O=C1C[C@@H]2COC[C@H](C1)C21OCCO1>>OC1C[C@@H]2COC[C@H](C1)C21OCCO1,,CO,ClCCl,[BH4-].[Na+],[Cl-].[NH4+],test
US20020040146A1,COC(=O)[C@H](CC(C)C)OC[C@@H]1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1S(C)(=O)=O>>CC(C)C[C@H](OC[C@@H]1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1S(C)(=O)=O)C(=O)O,,C1CCOC1,CCO,,,test
US04628104,C=C(C(=O)c1ccc(Cl)cc1Cl)c1ccc(C)cc1.c1c[nH]cn1>>Cc1ccc(C(Cn2ccnc2)C(=O)c2ccc(Cl)cc2Cl)cc1,,CCO,,,,test
US06720424B1,CCCCCCCCCCCCCCCCCCBr.Nc1ccc(O)cc1>>CCCCCCCCCCCCCCCCCCOc1ccc(N)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20050203027A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1CCCN1>>CC(C)(C)OC(=O)N1CCCC1,CN(C)c1ccncc1,CCN(CC)CC,,,,test
US04107182,CCOC(=O)CC#N.COc1c(O)c(C=O)cc2ccoc12.[OH-]>>COc1c2occc2cc2cc(C(=O)O)c(=O)oc12,,O,,Cl,,test
US20160159808A1,C=C(C)c1cnc2c(C(=O)NC(c3ccc(OC(F)(F)F)c(F)c3)C(C)(C)O)cnn2c1>>CC(C)c1cnc2c(C(=O)NC(c3ccc(OC(F)(F)F)c(F)c3)C(C)(C)O)cnn2c1,,C1CCOC1,,CO,,test
US20060264460A1,Cc1cc(C=O)n(C)n1.N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1>>Cc1cc(CNc2ccc3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)n(C)n1,,CCO,,[BH3-]C#N.[Na+],,test
US20030229164A1,CCCCCCN.O=C(O)C(O)C(O)C(=O)O>>CCCCCCN1C(=O)C(O)C(O)C1=O,,Cc1ccccc1,,,,test
US20160257690A1,Cc1cc(-c2c[nH]cn2)ccc1F.O=C1CCC(=O)N1Br>>Cc1cc(-c2nc[nH]c2Br)ccc1F,,CN(C)C=O,,,,test
US20050261350A1,COc1ccc(C(=O)Nc2cc3c(cc2[N+](=O)[O-])N(C(=O)Oc2ccc([N+](=O)[O-])cc2)C(=O)C3(C)C)cc1.NCc1ccccc1>>COc1ccc(C(=O)Nc2cc3c(cc2[N+](=O)[O-])N(C(=O)NCc2ccccc2)C(=O)C3(C)C)cc1,,ClCCl,,,,test
US20060189606A1,CCn1c(-c2ccc(OCCN=[N+]=[N-])cc2)c(C#N)c2ccc(OC)cc21>>CCn1c(-c2ccc(OCCN)cc2)c(C#N)c2ccc(OC)cc21,[Pd],CO,,Cl,,test
US20160214943A1,BrC(Br)(Br)Br.O=[N+]([O-])c1ccc(-n2cc(C(F)(F)F)nc2CO)cc1>>O=[N+]([O-])c1ccc(-n2cc(C(F)(F)F)nc2CBr)cc1,,ClCCl,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110306610A1,CCCCOc1nc(N)c2nc(OC)[nH]c2n1.COC(=O)c1ccccc1OCCBr>>CCCCOc1nc(N)c2nc(OC)n(CCOc3ccccc3C(=O)OC)c2n1,,CN(C)C=O,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20070004753A1,C[Si](C)(C)C#N.Cc1cc(N)n[nH]1.O=C1CCC1>>Cc1cc(NC2(C#N)CCC2)[nH]n1,,ClCCl,,,,test
US20100280221A1,CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)ON1C(=O)CCC1=O.NC(=O)CC[C@H](N)C(=O)O>>CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)O,,CC#N,O,O=C([O-])O.[Na+],,test
US20140275087A1,Cn1cnc(S(=O)(=O)N2C[C@@H](O)[C@H](c3ccc(F)cc3)C2)c1.Fc1cc(C(F)(F)F)ccn1>>Cn1cnc(S(=O)(=O)N2C[C@@H](Oc3cc(C(F)(F)F)ccn3)[C@H](c3ccc(F)cc3)C2)c1,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20080045556A1,CC(=O)c1ccn(C)c1.O=C=NS(=O)(=O)Cl>>CC(=O)c1cc(C#N)n(C)c1,,ClCCl,O,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20070111987A1,CC(=O)OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1>>OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1,,CCO,,[Na+].[OH-],,test
US04153723,ClCc1ccc(Cl)c(Cl)c1.N#CC(C#N)=CNc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>N#CC(C#N)=CN(Cc1ccc(Cl)c(Cl)c1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,CS(C)=O,,CC(C)(C)[O-].[K+],,test
US20100298295A1,BrBr.CC(=O)Cl.Nc1cccc2c1CCCC2>>CC(=O)Nc1ccc(Br)c2c1CCCC2,,ClCCl,,CCN(CC)CC,,test
US20090105305A1,Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NS(=O)(=O)CCN1C(=O)c2ccccc2C1=O>>Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NS(=O)(=O)CCN,,CCO,,NN,O,test
US20120059028A1,CCCC(C(=O)OC)c1c(C)nc2sc3c(c2c1-c1ccc(OC(F)(F)F)cc1)CCCC3>>CCCC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1ccc(OC(F)(F)F)cc1)CCCC3,,CO,,[Na+].[OH-],,test
US20090192156A1,CC(C)(C)OC(=O)N1CCC(OCC(=O)N2CCOCC2)CC1>>CC(C)(C)OC(=O)N1CCC(OCCN2CCOCC2)CC1,,C1CCOC1,,,,test
US04124726,CCCCc1ccccc1.O=C(Cl)c1ccccc1>>CCCCc1ccc(C(=O)c2ccccc2)cc1,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US05656573,CN(C)C=CC(=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-].NO>>O=[N+]([O-])c1cc(C(F)(F)F)ccc1C1(O)CC=NO1,,CCO,,Cl,,test
US06329381B1,CN(C)C=O.Nc1nc(S)nc2c1nc(O)n2Cc1ccccc1.O=C1c2ccccc2C(=O)N1CCBr>>Nc1nc(SCCCN2C(=O)c3ccccc3C2=O)nc2c1nc(O)n2Cc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05889178,CS(=O)(=O)OC[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1.[N-]=[N+]=[N-]>>[N-]=[N+]=NC[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1,,CN(C)C=O,,CCOC(C)=O,O,test
US05753664,Cn1c(=O)[nH]c(=O)c2[nH]cnc21.O=C(c1ccc(Cl)cc1)c1ccc(CBr)cc1>>Cn1c(=O)[nH]c(=O)c2c1ncn2Cc1ccc(C(=O)c2ccc(Cl)cc2)cc1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20150259286A1,CCC1(CC)CN(C(=O)OC(C)(C)C)c2c(OC)cccc21.O=C1CCC(=O)N1Br>>CCC1(CC)CNc2c(OC)cc(Br)cc21,,CC(C)=O,,CCCCCC,,test
US20010056109A1,O=C(O)C(=Cc1ccccc1)c1ccccc1>>O=C(O)C(Cc1ccccc1)c1ccccc1,[Pd],CCO,,,,test
US20030203926A1,CCN.O=C(O)CN1CCN(C(=O)c2ccc(Nc3nccc(-c4ccc(Cl)cc4)n3)cc2)CC1>>CCNC(=O)CN1CCN(C(=O)c2ccc(Nc3nccc(-c4ccc(Cl)cc4)n3)cc2)CC1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20070105904A1,O=[N+]([O-])/C=C/c1ccc(Oc2ccccn2)cc1>>O=[N+]([O-])CCc1ccc(Oc2ccccn2)cc1,,CS(C)=O,,CC(=O)O,[BH4-].[Na+],test
US20040044211A1,CCS(=O)(=O)Cl.CN1Cc2c(Cl)cc(Cl)cc2C(c2cccc(N)c2)C1>>CCS(=O)(=O)Nc1cccc(C2CN(C)Cc3c(Cl)cc(Cl)cc32)c1.Cl,CN(C)c1ccncc1,c1ccncc1,,,,test
US20090275570A1,CC(C)(C)OC(=O)N1CCC[C@H](N)C1.N#Cc1cnc(Cl)c2nc(-c3ccccc3)sc12>>CC(C)(C)OC(=O)N1CCC[C@H](Nc2ncc(C#N)c3sc(-c4ccccc4)nc23)C1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20040058894A1,C=CC(=O)OCc1ccccc1.COCN(Cc1ccccc1)C[Si](C)(C)C>>O=C(OCc1ccccc1)C1CCN(Cc2ccccc2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020120007A1,COc1ccc(C(=O)Nc2cccc(OOC(=O)c3ccc(OC)cc3)c2NC(=O)c2ccc(OC)cc2)cc1>>COc1ccc(C(=O)Nc2cccc(O)c2NC(=O)c2ccc(OC)cc2)cc1,,CO,,[Na+].[OH-],,test
US20080269220A1,CCOCCOc1cc(C)c(-c2cccc(CNc3ccc(CCC(=O)O)cn3)c2)c(C)c1.CS(=O)(=O)O>>CCOCCOc1cc(C)c(-c2cccc(CNc3ccc(CCC(=O)O)cn3)c2)c(C)c1.CS(=O)(=O)O,,CCOC(C)=O,CCOCC,,,test
US20100137313A1,Nc1ccccc1N.O=C(O)c1cnc(Nc2ccc(F)c(Cl)c2)nc1N1CCOCC1>>Nc1ccccc1NC(=O)c1cnc(Nc2ccc(F)c(Cl)c2)nc1N1CCOCC1,,CN(C)C=O,O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20030195200A1,CCOC(=O)/C=C(\C)c1ccc(I)cc1.OB(O)c1ccco1>>CCOC(=O)/C=C(\C)c1ccc(-c2ccco2)cc1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20140206618A1,CC(C)(C)OC(=O)N1CCN[C@H](CO)C1.C[C@@H]1Cc2cc(C3CO3)ccc2C(=O)O1>>C[C@@H]1Cc2cc(C(O)CN3CCN(C(=O)OC(C)(C)C)C[C@H]3CO)ccc2C(=O)O1,,CCO,,,,test
US20090298823A1,Clc1nc(Cl)c2cc[nH]c2n1.NCCCCN>>NCCCCNc1nc(Cl)nc2[nH]ccc12,,CCCCO,,CCN(CC)CC,,test
US05985871,NCCCO.O=C(O)c1cc2c(cc1O)OCO2>>O=C(NCCCO)c1cc2c(cc1O)OCO2,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20140315888A1,CC(C)(C)OC(=O)N1CCN(c2nc3nc(Cl)c(Cl)cc3n3cnnc23)CC1>>Clc1cc2c(nc1Cl)nc(N1CCNCC1)c1nncn12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130252941A1,Fc1cc(Cl)c(-n2cc3cncc(F)c3n2)c(Cl)c1.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1cc(F)c2nn(-c3c(Cl)cc(F)cc3Cl)cc2c1,,ClCCl,,,,test
US05100880,CCC[C@@H](NC(=O)N1C(=O)C(CC)(CC)[C@@H]1Oc1ccc(CBr)cc1)c1ccc(C)cc1.CCOP(OCC)OCC>>CCOP(=O)(Cc1ccc(OC2CC(=O)N2)cc1)OCC,,CCCCCC,,CCOC(C)=O,,test
US20090231663A1,O=Cc1ccc(N(c2ccccc2)c2ccc(C=O)cc2)cc1>>OCc1ccc(N(c2ccccc2)c2ccc(CO)cc2)cc1,,CCO,,[BH4-].[Na+],,test
US20100016319A1,C1COCCN1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(F)cc(Cl)c2Oc2ccnc(Cl)n2)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(F)cc(Cl)c2Oc2ccnc(N3CCOCC3)n2)cc1,,CCO,,,,test
US20110251223A1,CC(=O)OC(C)=O.CC(C)[Si](O[C@@H]1CC[C@@H](c2cccc(F)c2F)[C@H](O)c2cccnc21)(C(C)C)C(C)C>>CC(=O)O[C@@H]1c2cccnc2[C@H](O[Si](C(C)C)(C(C)C)C(C)C)CC[C@H]1c1cccc(F)c1F,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US07015218B1,N#Cc1cc([N+](=O)[O-])ccc1N(CCO)CCO>>N#Cc1cc(N)ccc1N(CCO)CCO,[Fe],CCO,,O,[Cl-].[NH4+],test
US04690889,O=C(Nc1cccc2c1C=CCC2(O)C(=O)O)C(F)(F)F.O=[N+]([O-])c1ccc(O)cc1>>O=C(Nc1cccc2c1C=CCC2(O)C(=O)Oc1ccc([N+](=O)[O-])cc1)C(F)(F)F,,CC#N,,CN(C)C=O,O=S(Cl)Cl,test
US20130184263A1,CC(=O)O[C@H](CNCc1ccc(Cl)cc1)[C@@]12CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(=O)CC(C)(C)C(=O)O)C(C)(C)[C@@H]5CC[C@]43C)C1=C(C(C)C)C(=O)C2.CN(C)CC=O>>CC(=O)O[C@H](CN(CCN(C)C)Cc1ccc(Cl)cc1)[C@@]12CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](OC(=O)CC(C)(C)C(=O)O)C(C)(C)[C@@H]5CC[C@]43C)C1=C(C(C)C)C(=O)C2,,CO,,Cl,[BH3-]C#N.[Na+],test
US04558040,Cc1ccc(NNC(=O)O)c2c1CCC(C)O2.ClCCl>>COC(=O)N=Nc1ccc(C)c2c1OC(C)CC2,,ClCCl,,O=C(OO)c1cccc(Cl)c1,,test
US04371546,CC(O)Oc1ccc(C(=O)c2ccc([N+](=O)[O-])cc2)c(Cl)c1Cl.CC=NO>>CC(O)Oc1ccc(C(=O)c2ccc(O)cc2)c(Cl)c1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20060270704A1,COc1ccc(C(=O)N(Cc2nccs2)C2CC2)c(C(=O)c2ccccc2)c1>>COc1ccc2c(c1)C(O)(c1ccccc1)C(c1nccs1)N(C1CC1)C2=O,,O,,,,test
US20100041635A1,NS(=O)(=O)c1ccc(-c2ccc(C=O)o2)cc1.O=C1Cc2cc(Cl)ccc2N1>>NS(=O)(=O)c1ccc(-c2ccc(C=C3C(=O)Nc4ccc(Cl)cc43)o2)cc1,,CCO,,C1CCNCC1,,test
US20050032790A1,CO.CS(=O)(=O)n1ccc2cc(F)c(OS(=O)(=O)C(F)(F)F)cc21.O=[PH2]C(CCc1ccccc1)c1ccccc1>>COC(=O)c1cc2c(ccn2S(C)(=O)=O)cc1F,[Pd],CCN(CC)CC,,CN(C)C=O,,test
US20100029611A1,CC(C)(C)C(=O)Nc1cccc(Cl)n1.ClC(Cl)(Cl)C(Cl)(Cl)Cl>>CC(C)(C)C(=O)Nc1nc(Cl)ccc1Cl,,C1CCOC1,,[Li]CCCC,,test
US20120214837A1,CCCc1nc(O)cc2cc(OC)c(OC)cc12.CNc1nc2cc3c(cc2cc1CCl)OCO3.Cl.ClCCl>>CCCc1nc(O)c(Cc2cc3cc4c(cc3nc2NC)OCO4)c2cc(OC)c(OC)cc12.Cl.Cl,,Cc1ccccc1,ClCCl,[Li+].[OH-],,test
US04824958,CCOc1cc(-c2ccccc2)sc1C(=O)OC>>CCOc1cc(-c2ccccc2)sc1C(=O)O,,C1CCOC1,O,[K+].[OH-],,test
US20060004011A1,COC(=O)C(=O)c1cc2ccccc2n1C(=O)OC(C)(C)C.Nc1ccccc1N>>O=c1[nH]c2ccccc2nc1-c1cc2ccccc2[nH]1,,CC(=O)O,,O=C(O)C(F)(F)F,,test
US20030186985A1,Cc1oc(-c2ccccc2)nc1COc1ccc(CO/N=C(\CCC(=O)O)c2ccccc2)cc1.[Li+]>>Cc1oc(-c2ccccc2)nc1COc1ccc(CO/N=C(\CCC(=O)[O-])c2ccccc2)cc1.[Li+],,CO,,O,,test
US20060084643A1,CC(C)c1cc2c(s1)Nc1ccccc1N=C2N.COCC[C@H]1CNCCN1>>COCC[C@H]1CN(C2=Nc3ccccc3Nc3sc(C(C)C)cc32)CCN1,,c1ccncc1,,Cl,,test
US20050267101A1,CC(C)(C)OC(=O)CC(N)C(O)CF.CCC[C@H](CC(=O)n1c2ccccc2c2ccccc21)C(=O)O>>CCCC(CC(=O)n1c2ccccc2c2ccccc21)C(=O)NC(CC(=O)OC(C)(C)C)C(O)CF,CN(C)c1ccncc1,C1CCOC1,,ClCCCl,On1nnc2ccccc21,test
US20150368265A1,CCOC(=O)c1c(C2=CCCC2)oc2cc(N)c(Br)cc12.CS(=O)(=O)Cl>>CCOC(=O)c1c(C2=CCCC2)oc2cc(NS(C)(=O)=O)c(Br)cc12,,ClCCl,,Cl,c1ccncc1,test
US04581355,BrCCc1ccccc1.O=C(NC1CCNCC1)c1c[nH]c2ccc(F)cc12>>O=C(NC1CCN(CCc2ccccc2)CC1)c1c[nH]c2ccc(F)cc12,,CN(C)C=O,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],,test
US20110275611A1,CN.CNc1nc(-c2cc(F)c(C#N)c(F)c2)cc(N2CCOC[C@H]2C)n1.NN>>CNc1nc(-c2cc(NC)c3c(N)n[nH]c3c2)cc(N2CCOC[C@H]2C)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04198533,C/C=C(C(=C/C)/c1ccc(O)cc1)\c1ccc(O)cc1.CCN(CC)CC.Cc1ccccc1.O=C1CCC(=O)N1Cl>>CC/C=C\C=C/CCCCCCCCCC=O,,Cc1ccccc1,O,CSC,,test
US05604229,CC(=O)NC(CC#Cc1ccccc1)(COC(C)=O)COC(C)=O>>NC(CO)(CO)CC#Cc1ccccc1,,CO,,[Na+].[OH-],,test
US20160264554A1,CNC.Nc1ccc(C(=O)N[C@H]2CCC[C@@H](Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)C2)cc1F.O=C(Cl)/C=C/CBr>>CN(C)C/C=C/C(=O)Nc1ccc(C(=O)N[C@H]2CCC[C@@H](Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)C2)cc1F,,C1CCOC1,CN1CCCC1=O,CCN(C(C)C)C(C)C,ClCCl,test
US04487773,CCC(=O)NNC(=O)NCCOc1ccccc1>>CCc1n[nH]c(=O)n1CCOc1ccccc1,,O,,Cl,[K+].[OH-],test
US20150018343A1,COC(=O)c1ccc(F)cc1OC(F)(F)C(F)F>>O=C(O)c1ccc(F)cc1OC(F)(F)C(F)F,,CO,,[Na+].[OH-],,test
US20110306631A1,COC(=O)C#CC(=O)OC.COc1ccc(N)c2ncccc12>>COC(=O)C=C(Nc1ccc(OC)c2cccnc12)C(=O)OC,,CO,,,,test
US20150158865A1,BrCCBr.Nc1cccc(Cl)c1>>Clc1cccc(NCCBr)c1,,CC#N,,,,test
US20040192921A1,C1CCNCC1.O=Cc1ccccc1F>>O=Cc1ccccc1N1CCCCC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150328224A1,CC(C)(C)OC(=O)N1[C@H]2CC[C@@H]1C[C@H]2Nc1cnc(C(F)(F)F)cn1.FC(F)(F)c1cnc(N[C@@H]2C[C@H]3CC[C@@H]2N3)cn1>>O=C(c1ccccc1-n1nccn1)N1[C@H]2CC[C@@H]1C[C@H]2Nc1cnc(C(F)(F)F)cn1,,C1COCCO1,CCOC(C)=O,Cl,,test
US20110281838A1,Cc1nc(N)nc(-c2ccc(S(C)(=O)=O)cc2)c1C#C[Si](C)(C)C>>C#Cc1c(C)nc(N)nc1-c1ccc(S(C)(=O)=O)cc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20090163463A1,Nc1ccccc1.O=S(=O)(Cl)c1cc(Br)ccc1Cl>>O=S(=O)(Nc1ccccc1)c1cc(Br)ccc1Cl,,ClCCl,,c1ccncc1,,test
US20150266867A1,CC(C)(C)OC(=O)NCc1cn(C[C@@H]2[C@H](NC(=O)/C(=N\OC3(C(=O)OC(c4ccccc4)c4ccccc4)CC3)c3csc(NC(=O)OC(C)(C)C)n3)C(=O)N2S(=O)(=O)O)nn1>>NCc1cn(C[C@@H]2[C@H](NC(=O)/C(=N\OC3(C(=O)O)CC3)c3csc(N)n3)C(=O)N2S(=O)(=O)O)nn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060079687A1,CCCN1Cc2cc(Oc3cccc(C(=O)O)c3)ccc2N=C1N.O=S(Cl)Cl>>CCCN1Cc2cc(Oc3cccc(C(=O)Cl)c3)ccc2N=C1N,,ClCCl,,,,test
US20050234244A1,COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(Cl)c(Cl)c1>>Cc1c(CC(=O)O)c2cc(O)ccc2n1C(=O)c1ccc(Cl)c(Cl)c1,,ClCCl,,BrB(Br)Br,,test
US20100278833A1,COC(=O)c1sc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)cc1O.Cc1ccccc1C(C)O>>COC(=O)c1sc(-n2cnc3cnc(CO[Si](C)(C)C(C)(C)C)cc32)cc1OC(C)c1ccccc1C,,ClCCl,,CC(C)(C)OC(=O)N=NC(=O)OC(C)(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050272669A1,BrCCCOCc1ccccc1.O=Cc1ccc(O)cc1>>O=Cc1ccc(OCCCOCc2ccccc2)cc1,,CN(C)C=O,O,[I-].[Na+],O=C([O-])[O-].[Cs+].[Cs+],test
US20160068559A1,CC1(C)O[C@@H]2[C@H](O1)[C@@H](CNCCCNC(=O)Nc1ccc(C(C)(C)C)cc1)O[C@H]2n1cnc2c(N)ncnc21.CCC(C)=O>>CCC(C)N(CCCNC(=O)Nc1ccc(C(C)(C)C)cc1)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20140349990A1,Cc1cc(Br)cnc1Cl.NN>>Cc1cc(Br)cnc1NN,,COCCO,,O,,test
US04339268,CC(C)(CO)[N+](=O)[O-].O=C(Cl)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]>>CC(C)(COC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-])[N+](=O)[O-],,CC(C)=O,,CCN(CC)CC,,test
US20090105233A1,NCc1cccnc1.O=C([O-])c1ccc2c(c1)nc(Cl)c1ccsc12>>O=C(O)c1ccc2c(c1)nc(NCc1cccnc1)c1ccsc12,,CN1CCCC1=O,CO,,,test
US06548042B2,COP(=O)(OC)C(O)(Cc1cccc([Si](C)(C)C)c1)P(=O)(OC)OC.NCc1ccccc1>>O=C(Cc1ccccc1)NCc1ccccc1,,ClC(Cl)Cl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20140275080A1,Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.O=[N+]([O-])c1ccc(Oc2ccnc(Cl)c2)cn1>>Cn1cc(-c2cc(Oc3ccc([N+](=O)[O-])nc3)ccn2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100048610A1,CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)cc(CCC)c1Oc1ccc(I)c(C=O)c1>>CCCc1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)cc(CCC)c1Oc1ccc(I)c(CO)c1,,CO,,O,[BH4-].[Na+],test
US20100130468A1,CC(C)C1CC2(CCS1)OCCO2>>CC(C)C1CC(=O)CCS1,,CC(=O)O,Cl,,,test
US03948918,COc1cc2[nH]c(C)c(CCN3CCN(N)CC3)c2cc1OC.O=C=Nc1ccccc1>>COc1cc2[nH]c(C)c(CCN3CCN(NC(=O)Nc4ccccc4)CC3)c2cc1OC,,CCOCC,,ClCCl,,test
US05594141,BrBr.Cc1ccnc(-c2ccccc2)c1>>BrCc1ccnc(-c2ccccc2)c1,,ClC(Cl)(Cl)Cl,,O=C([O-])[O-].[Na+].[Na+],,test
US20020132796A1,COC(=O)Cc1ccc(C#Cc2ccc(C3(OC(C)C)CC3)cc2)cc1>>CC(C)OC1(c2ccc(C#Cc3ccc(CC(=O)O)cc3)cc2)CC1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20090186879A1,CCC(O)(CC)c1cccc2[nH]c(=O)[nH]c12>>CCC(CC)c1cccc2[nH]c(=O)[nH]c12,[Pd],CC(=O)O,,Cl,,test
US20140213586A1,COc1cccc(N)c1.COc1cncc(C=O)c1>>COc1cncc(C=Nc2cccc(OC)c2)c1,,CCO,,,,test
US20070232673A1,Cl.Cn1c(=N)n(CSc2ccc(Cl)cc2)c2ccccc21.O=C(OO)c1cccc(Cl)c1>>Cl.Cn1c(=N)n(CS(=O)c2ccc(Cl)cc2)c2ccccc21,,CCOC(C)=O,ClCCl,,,test
US20020143022A1,COC(=O)c1ccc2[nH]ccc2c1.ClCc1ccc(Cl)cc1Cl>>COC(=O)c1ccc2c(ccn2Cc2ccc(Cl)cc2Cl)c1,,O,,CN(C)C=O,[H-].[Na+],test
US20120041009A1,CCOC(=O)CC(=O)C(F)(F)C(F)(F)F.N=C(N)C1CC1>>Oc1cc(C(F)(F)C(F)(F)F)nc(C2CC2)n1,,CCO,,Cl,O=C([O-])O.[Na+],test
US20090326074A1,CC#N.O=Cc1cccc(O)c1>>N#CCC(O)c1cccc(O)c1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20020007062A1,CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1O.Nc1ccc([N+](=O)[O-])cc1.O=C(O)CS>>CC(C)(C)c1cc(C2SCC(=O)N2c2ccc([N+](=O)[O-])cc2)cc(C(C)(C)C)c1O,,Cc1ccccc1,,CC(=O)O,,test
US06573289B1,CC(C)C[Mg]Br.COc1ccc2cc(C(=O)c3c[nH]cn3)ccc2c1>>COc1ccc2cc(C(O)(CC(C)C)c3c[nH]cn3)ccc2c1,,C1CCOC1,,,,test
US20140200227A1,C[C@H]1CN(C(=O)OCc2ccccc2)C[C@@H](NC(=O)OC(C)(C)C)[C@]1(C)O>>C[C@H]1CNC[C@@H](NC(=O)OC(C)(C)C)[C@]1(C)O,[Pd],CO,,,,test
US20120010228A1,CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCNCC3)C2=O)c1.Fc1ccc(C(CCCCl)c2ccc(F)cc2)cc1>>CC(C)(C)OC(=O)c1cccc(CN2CN(c3ccccc3)C3(CCN(CCCC(c4ccc(F)cc4)c4ccc(F)cc4)CC3)C2=O)c1,,CCC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20080161328A1,CCOC(=O)Cl.Cc1nc2cccc(N)c2c(=O)n1C1CCC(=O)NC1=O>>CCOC(=O)Nc1cccc2nc(C)n(C3CCC(=O)NC3=O)c(=O)c12,,C1CCOC1,,,,test
US20060128695A1,COC(=O)CN.COc1cc2c(=O)oc(=O)n(C)c2cc1OC>>COc1cc2c(cc1OC)N(C)C(=O)CNC2=O,,c1ccncc1,,CC(=O)O,Cl,test
US20160108056A1,COc1cc(-c2ccc(F)cc2F)cc([N+](=O)[O-])c1>>O=[N+]([O-])c1cc(O)cc(-c2ccc(F)cc2F)c1,,ClCCl,,BrB(Br)Br,CO,test
US04673746,CCOC(=O)CBr.COc1ccc2c(-c3ccccc3F)noc2c1Br>>CCOC(=O)COc1ccc2c(-c3ccccc3F)noc2c1Br,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080262042A1,Cc1c(S(=O)(=O)n2cc(CN(C)C(=O)OC(C)(C)C)c(F)c2-c2cccnc2F)cnn1C.Cl>>CNCc1cn(S(=O)(=O)c2cnn(C)c2C)c(-c2cccnc2F)c1F.Cl,,CCO,,CCOC(C)=O,,test
US20110098320A1,C=CCC(CCN[C@@H](C)c1ccc(Br)cc1)(CC(=O)OCC)c1ccccc1>>C=CC[C@]1(c2ccccc2)CCN([C@@H](C)c2ccc(Br)cc2)C(=O)C1,,Cc1ccccc1,,,,test
US20140212382A1,CCOC(=O)CCc1ccccc1OP(=O)(N[C@@H](C)C(=O)OCC)Oc1ccc(S(C)(=O)=O)cc1.CSc1ccc(O)cc1>>CCOC(=O)CCc1ccccc1OP(=O)(N[C@@H](C)C(=O)OCC)Oc1ccc(SC)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04137313,COC(=O)C1=C(O)c2c(c3ccccc3n2C)S(=O)(=O)N1.Nc1nccs1>>Cn1c2c(c3ccccc31)S(=O)(=O)NC(C(=O)Nc1nccs1)=C2O,,Cc1ccccc1C,,,,test
US20120059028A1,CCCI.COC(=O)Cc1c(C)nc2sc3c(c2c1-c1ccccc1)CCC3>>CCCC(C(=O)OC)c1c(C)nc2sc3c(c2c1-c1ccccc1)CCC3,,CN(C)C=O,,C1CCOC1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US05036075,CC(CCBr)N1CCN(c2ccc(F)cc2)CC1.O=S1(=O)Nc2cccc3cccc1c23>>CC(CCN1c2cccc3cccc(c23)S1(=O)=O)N1CCN(c2ccc(F)cc2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20040006099A1,CCOC(=O)C1(COc2ccc3c(c2)CN(C(=O)OCc2ccccc2)CC3)CCN(C(=O)OC(C)(C)C)CC1>>CCOC(=O)C1(COc2ccc3c(c2)CN(C(=O)OCc2ccccc2)CC3)CCNCC1,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20050250822A1,C=C(c1ccc(N2C(=O)c3cccc(I)c3C2=O)c(C)c1)C(F)(F)F.CC(=O)OCC(Cl)=NO>>CCOC(=O)C1=NOC(c2ccc(N3C(=O)c4cccc(I)c4C3=O)c(C)c2)(C(F)(F)F)C1,O,COCCOC,,O=C([O-])O.[K+],,test
US20130065881A1,COc1ccc(-c2nnc3c4c(c(Cl)nn23)OCCN4C)cc1>>CN1CCOc2c(Cl)nn3c(-c4ccc(O)cc4)nnc3c21,,ClCCl,ClCCl,,,test
US20040132727A1,COc1cc2nccc(Oc3cc(C)c(N)cc3C)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.OCCCOc1ccccc1F>>COc1cc2nccc(Oc3cc(C)c(NC(=O)OCCCOc4ccccc4F)cc3C)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20060079554A1,CC(C)(C)OC(=O)N1CCC(NCc2ccc(F)cc2C(F)(F)F)CC1.CC1(C)CO1>>CC(C)(O)CN(Cc1ccc(F)cc1C(F)(F)F)C1CCN(C(=O)OC(C)(C)C)CC1,,CO,,O=C([O-])O.[Na+],,test
US20130096118A1,CC(=O)c1ccc2c(c1)[nH]c1c(C(N)=O)ncc(-c3cccc(-n4cnc5ccccc5c4=O)c3C)c12>>Cc1c(-c2cnc(C(N)=O)c3[nH]c4cc(C(C)O)ccc4c23)cccc1-n1cnc2ccccc2c1=O,,C1CCOC1,CO,[BH4-].[Na+],,test
US20100273764A1,CSc1nc(C)nc(Cl)n1.OB(O)c1cc(C2OCCO2)cnc1F>>CSc1nc(C)nc(-c2cc(C3OCCO3)cnc2F)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20120145959A1,CCCC1CCC2CC(C3CCC(COS(=O)(=O)c4ccc(C)cc4)CC3)CCC2C1.CCOc1ccc(O)c(F)c1F>>CCCC1CCC2CC(C3CCC(COc4ccc(OCC)c(F)c4F)CC3)CCC2C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150166480A1,CC(C)(O)CN1CCC(COc2cnc(Cl)nc2)CC1.CCN(CC)S(F)(F)F>>CC(C)(F)CN1CCC(COc2cnc(Cl)nc2)CC1,,ClCCl,,O,,test
US20070244159A1,Cn1c(C(C)(C)C)cc2cc([N+](=O)[O-])ccc21>>Cn1c(C(C)(C)C)cc2cc(N)ccc21,[Ni],CO,,,,test
US06136823,CCOC(=O)c1cn(-c2ccc(F)c(OC)c2)c2c(C)c(F)c(F)cc2c1=O>>COc1cc(-n2cc(C(=O)O)c(=O)c3cc(F)c(F)c(C)c32)ccc1F,,CC(=O)O,,Cl,,test
US05665718,CCCI.CCN(C(C)C)C(C)C.CN(C)C=O.NCc1noc(-c2ncn3c2[C@@H]2CCCN2C(=O)c2c(Cl)cccc2-3)n1>>CCCN(CCC)Cc1noc(-c2ncn3c2[C@@H]2CCCN2C(=O)c2c(Cl)cccc2-3)n1,,CN(C)C=O,,,,test
US20060069110A1,CCOC1(O[Si](C)(C)C)CC1.CN(c1ccnc(N[C@@H](CCN)Cc2ccccc2)n1)c1ccnc(-c2ccccc2)n1>>CN(c1ccnc(N[C@@H](CCNC2CC2)Cc2ccccc2)n1)c1ccnc(-c2ccccc2)n1,CC(=O)O,CO,,[BH3-]C#N.[Na+],,test
US20100168430A1,O=C(Nc1ccc(Oc2ccnc3[nH]ncc23)cc1)Nc1ccc(Oc2ccc(F)cc2)c(C(F)(F)F)c1.O=CC(=O)O>>O=c1n(-c2ccc(Oc3ccnc4[nH]ncc34)cc2)c(O)c(O)n1-c1ccc(Oc2ccc(F)cc2)c(C(F)(F)F)c1,,Cc1ccccc1,,,,test
US20150299188A1,Cc1ccc(OCc2ncccc2F)cc1NC(=O)c1ncccc1N.O=C(n1ccnc1)n1ccnc1>>Cc1ccc(OCc2ncccc2F)cc1-n1c(=O)[nH]c2cccnc2c1=O,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20120214802A1,CC(C)(C)OC(=O)N1C[C@H](OCc2ccccc2)C[C@@H]1[C@@H](O)[C@@H](N)Cc1ccccc1.Cc1csc([C@H]2CCCN2C(=O)c2cc(CF)cc(C(=O)O)c2)n1>>Cc1csc([C@H]2CCCN2C(=O)c2cc(CF)cc(C(=O)N[C@@H](Cc3ccccc3)[C@H](O)[C@H]3C[C@@H](OCc4ccccc4)CN3C(=O)OC(C)(C)C)c2)n1,,ClCCl,O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20050288282A1,COc1cc(C2C=CC(c3ccc(C(=O)Nc4ccccc4N)cc3)O2)cc(OC)c1OC>>COc1cc(C2CCC(c3ccc(C(=O)Nc4ccccc4N)cc3)O2)cc(OC)c1OC,O=[Pt]=O,CCOC(C)=O,,,,test
US04897405,Cc1ccc2cccc(Br)c2c1.O=C1CCC(=O)N1Br>>BrCc1ccc2cccc(Br)c2c1,CC(C)(C#N)N=NC(C)(C)C#N,ClC(Cl)(Cl)Cl,,,,test
US04154834,CI.O=c1[nH]c(=S)[nH]cc1Cc1cccs1>>CSc1ncc(Cc2cccs2)c(=O)[nH]1,,CCO,,O,[Na+].[OH-],test
US20080139505A1,CCCc1c(OCc2ccc(C(O)c3cccc(C#N)c3)cc2)ccc(C(C)=O)c1O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CCCc1c(OCc2ccc(C(N=[N+]=[N-])c3cccc(C#N)c3)cc2)ccc(C(C)=O)c1O,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20050277037A1,NNc1ccccc1.O=Cc1scc2c1OCCO2>>C(=NNc1ccccc1)c1scc2c1OCCO2,,CO,,,,test
US20100324046A1,COC(=O)c1ccc(CNS(=O)(=O)c2ccc([N+](=O)[O-])cc2[N+](=O)[O-])cc1.C[Si](C)(C)Cn1cc(CO)nn1>>COC(=O)c1ccc(CN(Cc2cn(C[Si](C)(C)C)nn2)S(=O)(=O)c2ccc([N+](=O)[O-])cc2[N+](=O)[O-])cc1,,CCOC(C)=O,c1ccccc1,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030078426A1,Cl.Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccc(Oc3ccc(CCN)cc3)cc21.O=S(=O)(Cl)c1ccc(Cl)cc1>>Cl.Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccc(Oc3ccc(CCNS(=O)(=O)c4ccc(Cl)cc4)cc3)cc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,Cl,test
US20150038437A1,CCCC(=O)N(C)OC.Cn1ccc2cc(Br)ccc21>>CCCC(=O)c1ccc2c(ccn2C)c1,,C1CCOC1,,[Li]CCCC,,test
US20130059849A1,CC(C)(C)OC(=O)NCCBr.CCOC(=O)c1cc(C2CC2)nc2[nH]ncc12>>CCOC(=O)c1cc(C2CC2)nc2c1cnn2CCNC(=O)OC(C)(C)C,,CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US20070249579A1,COc1cc[n+]([O-])c2[nH]cc(C(=O)C(=O)O)c12.c1ccc(-n2nnnc2N2CCNCC2)cc1>>COc1cc[n+]([O-])c2[nH]cc(C(=O)C(=O)N3CCN(c4nnnn4-c4ccccc4)CC3)c12,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20050182059A1,CCCOc1ccc(N)nn1.O=C1c2ccccc2CC1Br>>CCCOc1ccc2nc3c(n2n1)Cc1ccccc1-3,,CCO,,O=C([O-])O.[Na+],,test
US20110021511A1,C1CNCCN1.CCOc1nc(Cl)nc2c1[nH]c1ccc(Br)cc12>>CCOc1nc(N2CCNCC2)nc2c1[nH]c1ccc(Br)cc12,,Cc1cc(C)cc(C)c1,,,,test
US20080021010A1,CC(C)(C)OC(=O)N1CC(C#N)(c2ccccn2)C1.Cl>>Cl.N#CC1(c2ccccn2)CNC1,,C1COCCO1,,,,test
US20100249146A1,CNCCCN(C)C.O=S(=O)(Cl)c1cnc(Cl)c(Cl)c1>>CN(C)CCCN(C)S(=O)(=O)c1cnc(Cl)c(Cl)c1,,O,,C1CCOC1,CCN(CC)CC,test
US20030232818A1,CC1(C)C(=O)N(Br)C(=O)N1Br.CCOC(=O)c1cn(CCC#N)c2nc(N3CCC3)ccc2c1=O>>CCOC(=O)c1cn(CCC#N)c2nc(N3CCC3)c(Br)cc2c1=O,,ClC(Cl)Cl,,,,test
US20040115732A1,C=CCCCCCCCCC(=O)Cl.CCOC(=O)CC(=O)[O-]>>C=CCCCCCCCCC(=O)CC(=O)OCC,,C1CCOC1,,[Li]CCCC,,test
US20090170882A1,Clc1ncc(Br)c(Cl)n1.Nc1cccc(C(F)(F)F)c1>>FC(F)(F)c1cccc(Nc2nc(Cl)ncc2Br)c1,,CCO,,O=C([O-])O.[Na+],,test
US20110097365A1,CN[Si](C)(C)C.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CC[Si](C)(C)NC(=O)c1ccc([N+](=O)[O-])cc1,,ClCCl,,CCN(CC)CC,O,test
US20120202856A1,BrCCOCc1ccccc1.CCOC(=O)c1cc(C(C)(C)C)n[nH]1>>CCOC(=O)c1cc(C(C)(C)C)nn1CCOCc1ccccc1,,CC#N,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20020052322A1,CCOC(=O)[C@@H](N)C(C)C.C[C@H](NC(=O)Cc1cccc([N+](=O)[O-])c1)C(=O)O>>CCOC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)Cc1cccc([N+](=O)[O-])c1)C(C)C,,CO,ClC(Cl)Cl,Cl,,test
US20060111375A1,COc1cc2nccc(Oc3cc4ccccc4nc3C)c2cc1O.ClCCBr>>COc1cc2nccc(Oc3cc4ccccc4nc3C)c2cc1OCCCl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040063170A1,COCc1ccc(Cc2ccc(OC)cc2)c(O[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)c1>>COCc1ccc(Cc2ccc(OC)cc2)c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1,,CO,,C[O-].[Na+],,test
US20160039804A1,CCN(c1ncc(Br)nc1C=O)C1CCCCC1>>CCN(c1ncc(Br)nc1CO)C1CCCCC1,,CO,,[BH4-].[Na+],,test
US20070129416A1,C1CCNC1.O=C(O)c1cc(S(=O)(=O)Cl)ccc1O>>O=C(O)c1cc(S(=O)(=O)N2CCCC2)ccc1O,,C1CCOC1,,Cl,,test
US05393755,CCOC(OCC)OCC.Cn1c(=O)[nH]c(N)c(NCc2ccccc2)c1=O>>Cn1c(=O)[nH]c2ncn(Cc3ccccc3)c2c1=O,,CN(C)C=O,,,,test
US20110318417A1,C[C@@H](N)c1cccc2ccccc12.O=CC=Cc1cccc(C(F)(F)F)c1>>C[C@@H](NCCCc1cccc(C(F)(F)F)c1)c1cccc2ccccc12,,CO,O,Cl,[BH4-].[Na+],test
US20140329794A1,C1COCCN1.COC(=O)c1cccc(C=O)c1>>COC(=O)c1cccc(CN2CCOCC2)c1,,CO,,[BH3-]C#N.[Na+],,test
US05344843,CCC(C)(C)C(=O)OCc1cccc(C)c1C#CCOc1ccc(C(=O)C(=O)OC)cc1>>CCC(C)(C)C(=O)OCc1cccc(C)c1C#CCOc1ccc(C(=O)C(=O)O)cc1,,CO,,[Na+].[OH-],,test
US20100173880A1,CC(=O)c1ccccc1N.CCOC(=O)C(Br)c1ccccc1>>CCOC(=O)C(Nc1ccccc1C(C)=O)c1ccccc1,,CC#N,,CCN(C(C)C)C(C)C,[I-].[K+],test
US05597825,CC(C)(C)OC(=O)COc1ccc(-c2ccc(C#N)cc2)cc1>>N#Cc1ccc(-c2ccc(OCC(=O)O)cc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080045556A1,CC(C)(N)CO.Clc1nc(-c2ccc(Br)cc2)ns1>>CC(C)(CO)Nc1nc(-c2ccc(Br)cc2)ns1,,CCOC(C)=O,,,,test
US08394858B2,COc1cc(S(=O)(=O)Cl)ccc1O.C[C@@H](NC(=O)[C@@H]1CC[C@@H](N)CC1)c1ccc(F)cc1>>COc1cc(S(=O)(=O)N[C@@H]2CC[C@@H](C(=O)N[C@H](C)c3ccc(F)cc3)CC2)ccc1O,,ClCCl,,CCN(CC)CC,Cl,test
US20140088079A1,Clc1ccc(Br)cc1Cc1ccc2c(c1)OCCO2.O=C1S[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1>>OC1(c2ccc(Cl)c(Cc3ccc4c(c3)OCCO4)c2)S[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US05552437,CCC(O)(c1cccc(CO[Si](C)(C)C(C)(C)C)n1)c1nccs1.CI>>CCC(OC)(c1cccc(CO[Si](C)(C)C(C)(C)C)n1)c1nccs1,,C1CCOC1,,,,test
US20060247210A1,COc1ccc(-c2n[nH]cc2-c2nc3ccccc3s2)cc1>>Oc1ccc(-c2n[nH]cc2-c2nc3ccccc3s2)cc1,,ClCCl,,BrB(Br)Br,,test
US20150336979A1,Cc1ccc(S(=O)(=O)O[C@@H]2CO[C@@H]3[C@@H](N)CO[C@H]23)cc1.O=C=NC1CCCCC1>>Cc1ccc(S(=O)(=O)O[C@@H]2CO[C@@H]3[C@@H](NC(=O)NC4CCCCC4)CO[C@H]23)cc1,,ClCCl,,CCN(CC)CC,,test
US20080242666A1,Cc1nnc(N)s1.N#Cc1ccc(F)cc1>>Cc1nnc(Nc2ccc(C#N)cc2)s1,,CS(C)=O,O,Cl,CC(C)(C)[O-].[K+],test
US04621901,COC=CC[C@@H]1CC[C@@H](c2ccc(C#N)cc2)CC1>>N#Cc1ccc([C@@H]2CC[C@@H](CCC=O)CC2)cc1,,C1CCOC1,,O,,test
US20150018377A1,CC[C@@H](NC(=O)OC(C)(C)C)C(=O)Nc1ccc(Oc2cccc(C(C)C)c2)nc1>>CC[C@@H](N)C(=O)Nc1ccc(Oc2cccc(C(C)C)c2)nc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140329794A1,COC(=O)c1cccc(OCCN(C)C)c1.NCC(O)CN1CCc2ccccc2C1>>CN(C)CCOc1cccc(C(=O)NCC(O)CN2CCc3ccccc3C2)c1,,CCO,,,,test
US20020028832A1,CC(C)(C)[Si](Oc1ccc(OC[C@@H](O)CNCCc2ccc(NC3CCN(C(=O)NCCCc4cccs4)CC3)cc2)cc1)(c1ccccc1)c1ccccc1>>O=C(NCCCc1cccs1)N1CCC(Nc2ccc(CCNC[C@H](O)COc3ccc(O)cc3)cc2)CC1,,CO,ClC(Cl)Cl,,,test
US20140088124A1,COC(=O)C(C)(C)COC1CCNCC1.O=Cc1ccc(F)nc1>>COC(=O)C(C)(C)COC1CCN(c2ccc(C=O)cn2)CC1,,CN1CCCC1=O,,O,O=C([O-])O.[Na+],test
US20050107364A1,CC[C@H](C)CCC1(C)C(=O)C(C2=NS(=O)(=O)c3cc(NC(=O)OC(C)(C)C)ccc3N2)=C(O)c2ccccc21.Cl>>CC[C@H](C)CCC1(C)C(=O)C(C2=NS(=O)(=O)c3cc(N)ccc3N2)=C(O)c2ccccc21.Cl,,C1COCCO1,,,,test
US20150094328A1,CC(C)(C)OC(=O)n1cc(C(=O)N[C@H]2CCCC[C@@H]2O)c2nccc(C#N)c21>>N#Cc1ccnc2c(C(=O)N[C@H]3CCCC[C@@H]3O)c[nH]c12,,ClCCl,,O=C(O)C(F)(F)F,,test
US04835165,CS(=O)(=O)Cl.Nc1ccc(C2CCN(c3ccncc3)CC2)cc1>>CS(=O)(=O)Nc1ccc(C2CCN(c3ccncc3)CC2)cc1,,c1ccncc1,,,,test
US20070254874A1,BrCc1ccccc1.Cl.O=C(O)CCC1CCNCC1>>Cl.O=C(O)CCC1CCN(Cc2ccccc2)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140045823A1,CC(C)OC(=O)Cl.O=C(c1cnc(-n2ccnc2)nc1)N(C1CCNCC1)C1CC1>>CC(C)OC(=O)N1CCC(N(C(=O)c2cnc(-n3ccnc3)nc2)C2CC2)CC1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20100256097A1,CC(C)(O)c1cc(F)c(-c2cc(C(N)=O)c(Nc3cccc(C(=O)CF)n3)s2)c(F)c1>>CC(C)(O)c1cc(F)c(-c2cc(C(N)=O)c(Nc3cccc(C(O)CF)n3)s2)c(F)c1,,CO,,[BH4-].[Na+],,test
US20120323005A1,CCOC(=O)C[C@H]1C[C@@H](COC(C)=O)OC(C)(C)O1>>COC(=O)C[C@H]1C[C@@H](CO)OC(C)(C)O1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20120040020A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncc(Br)nc1-c1nnc(-c2ccccc2)o1.CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1>>CC(C)(C)OC(=O)N1CC=C(c2cnc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(-c3nnc(-c4ccccc4)o3)n2)CC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20120101127A1,CC(C)(N)C(=O)O.Cc1ccc2c(c1)C(C)(C)CC(c1cccc(Br)c1)N2>>Cc1ccc2c(c1)C(C)(C)CC(c1cccc(NC(C)(C)C(=O)O)c1)N2,[Cu]I,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080214614A1,CC(C)(C)OC(=O)n1nc(N)c2cc(N)ccc21.O=C1CCCN(Cc2ccccc2)C1>>Nc1n[nH]c2ccc(NC3CCCN(Cc4ccccc4)C3)cc12,,CO,,[BH3-]C#N.[Na+],,test
US20100048564A1,CN(C(=O)OC(C)(C)C)c1cc(Cl)ccc1[N+](=O)[O-].Cc1cccc(O)c1>>Cc1cccc(Oc2ccc([N+](=O)[O-])c(N(C)C(=O)OC(C)(C)C)c2)c1,,CN(C)C=O,,[H-].[Na+],,test
US04118561,CI.Nc1nc(N)c2c(ccc3[nH]ccc32)n1>>Cn1ccc2c3c(N)nc(N)nc3ccc21,,CC(=O)O,CN(C)C=O,[H-].[Na+],O=C([O-])[O-].[K+].[K+],test
US20060160832A1,CCN(CC)CCCOc1cc2nccc(Sc3ccc([N+](=O)[O-])s3)c2cc1OC>>CCN(CC)CCCOc1cc2nccc(Sc3ccc(N)s3)c2cc1OC,[Fe],O,,CCO,[Cl-].[NH4+],test
US05449812,CCOC(=O)N=C=S.CNc1ccc(C(=O)OC)c(S(=O)(=O)NC(C)(C)C)c1>>CCOC(=O)NC(=S)CNc1ccc(C(=O)OC)c(S(=O)(=O)NC(C)(C)C)c1,,CCOC(C)=O,CN(C)C=O,,,test
US20160251368A1,CCOC(=O)c1c2n(c(=O)c3c(OC)c(OC)ccc13)CCc1cc3c(cc1-2)OCO3>>COc1ccc2c(C(=O)O)c3n(c(=O)c2c1OC)CCc1cc2c(cc1-3)OCO2,,[Na+],[OH-],,,test
US20080312270A1,C1CCNC1.COc1ccc(C=C(Br)Br)c(C)c1C.O>>COc1ccc(CC(=O)N2CCCC2)c(C)c1C,,CCOCC,O,CN(C)C=O,,test
US05294612,CCOC(CC)=C(C#N)C#N.NNC1CCCC1>>CCc1nn(C2CCCC2)c(N)c1C#N,,CCO,,Cl,C[O-].[Na+],test
US20080261969A1,Cc1ccc2nc(S)[nH]c2c1.O=Cc1ccc([N+](=O)[O-])o1>>Cc1ccc2[nH]c(Sc3ccc(C=O)o3)nc2c1,,C1CCOC1,,O,[H-].[Na+],test
US04603015,C=CC#N.NCCCCNC(=O)C(O)C(O)C(=O)O>>N#CCCNCCCCNC(=O)C(O)C(O)C(=O)O,,O,,CCN(CC)CC,,test
US20090281088A1,C=C(COC1COc2nc([N+](=O)[O-])cn2C1)c1ccc(N2CC(CNC(C)=O)OC2=O)cc1F.O=[Os](=O)(=O)=O>>CC(=O)NCC1CN(c2ccc(C(=O)COC3COc4nc([N+](=O)[O-])cn4C3)c(F)c2)C(=O)O1,O=[Os](=O)(=O)=O,,,CO,,test
US04182757,CCCCCCN(C(=O)NCCCl)C1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O.O=[N+]([O-])[N+](=O)[O-]>>CCCCCCN(C(=O)N(CCCl)N=O)C1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O,,C1CCOC1,ClCCl,O=C([O-])[O-].[Na+].[Na+],,test
US20130005719A1,CCOC/C=C/c1ccc(C(F)(F)C(O)(Cn2cnnn2)c2ccc(F)cc2F)nc1>>CCOCCCc1ccc(C(F)(F)C(O)(Cn2cnnn2)c2ccc(F)cc2F)nc1,[Pd],CCO,,,,test
US20020115861A1,CC(C)CNc1c(N)cnc2ccccc12.COCC(=O)O>>COCc1nc2cnc3ccccc3c2n1CC(C)C,,O,,[Na+].[OH-],,test
US05624950,CCCCOCN(Cc1ccccc1)C[Si](C)(C)C.COC1(OC)C=CC(=O)C=C1>>COC1(OC)C=CC(=O)C2CN(Cc3ccccc3)CC21,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US05523457,CC(=O)Nc1cccc2ccc(O)cc12.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(=O)Nc1cccc2ccc(OS(=O)(=O)C(F)(F)F)cc12,CN(C)c1ccncc1,ClCCl,,,,test
US20160130226A1,O=C1CCC(=O)N1Br.O=C1Cc2ccc(Cl)c(Cl)c2N1>>O=C1Cc2cc(Br)c(Cl)c(Cl)c2N1,,CC#N,,,,test
US20050256140A1,CSc1ncnc2sc(-c3c(-c4ccccc4)nc(Br)n3C)nc12.OB(O)c1ccccc1>>CSc1ncnc2sc(-c3c(-c4ccccc4)nc(-c4ccccc4)n3C)nc12,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20070249612A1,CC(C)Nc1nc(-c2cccc(C(=O)O)c2)cn2c(=O)n(C(C)(C)C)nc12.NCCc1ccccc1>>CC(C)Nc1nc(-c2cccc(C(=O)NCCc3ccccc3)c2)cn2c(=O)n(C(C)(C)C)nc12,,CCOC(C)=O,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US20150291595A1,CCCC[Sn](CCCC)(CCCC)c1nccs1.Cc1ccn2nc([C@H](C)Nc3ncnc(N)c3I)n(-c3ccccc3)c(=O)c12>>C[C@H](Nc1ncnc(N)c1-c1nccs1)c1nn2cccc2c(=O)n1-c1ccccc1,[Cu]I,CN(C)C=O,,CCN(CC)CC,,test
US20100249123A1,CC(=O)NCC(C)(C)c1ccc(N)cc1Cl.COc1ccc(C(=O)Cl)cc1OC>>COc1ccc(C(=O)Nc2ccc(C(C)(C)CNC(C)=O)c(Cl)c2)cc1OC,,ClCCl,,CCN(CC)CC,CN(C)C=O,test
US04879382,CN1c2ccncc2NCc2cccn21.CN=C=O>>CNC(=O)N1Cc2cccn2N(C)c2ccncc21,,c1ccccc1,,,,test
US20130225620A1,Cc1ccc(S(=O)(=O)n2ccc3c(C(C)Br)cccc32)cc1.O=C1NC(=O)c2ccccc21>>Cc1ccc(S(=O)(=O)n2ccc3c(C(C)N4C(=O)c5ccccc5C4=O)cccc32)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04728646,Clc1nc(N2CCOCC2)c2ncnc(NCc3ccccc3)c2n1.OCCN1CCNCC1>>OCCN1CCN(c2nc(N3CCOCC3)c3ncnc(NCc4ccccc4)c3n2)CC1,,C1COCCO1,,,,test
US20040259857A1,CCOC(=O)CCCC1(C(=O)OCC)CCN(S(=O)(=O)c2ccc(C)cc2)c2ccccc2C1>>CCOC(=O)C1CCC2(CCN(S(=O)(=O)c3ccc(C)cc3)c3ccccc3C2)C1=O,,Cc1ccccc1,,Cl,CC(C)(C)[O-].[K+],test
US20060252790A1,CC(C)(C)OC(=O)NN.CCn1ncc2c(NC3CCOCC3)c(C(=O)O)c(C)nc21>>CCn1ncc2c(NC3CCOCC3)c(C(=O)NNC(=O)OC(C)(C)C)c(C)nc21,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20080171741A1,Cc1ccc(C(=O)NC2CC2)cc1N.O=C(O)CS>>Cc1ccc(C(=O)NC2CC2)cc1NC(=O)CS,,Cc1ccccc1,,Cl,,test
US05840917,NP(N)(=O)NC(=O)C=Cc1ccccc1>>NP(N)(=O)NC(=O)CCc1ccccc1,,CO,,,,test
US20080247964A1,C1CC(N2CCC3(CCNCC3)C2)C1.Clc1ccc(Br)cn1>>Brc1ccc(N2CCC3(CC2)CCN(C2CCC2)C3)nc1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US07297693B2,CON=C1CCc2cc(-c3cc(C(=O)OC(C)(C)C)oc3-c3ccncc3)ccc21.O=C(O)C(F)(F)F>>CON=C1CCc2cc(-c3cc(C(=O)O)oc3-c3ccncc3)ccc21.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20130196974A1,CC(C)(C)OC(=O)NC1(CO)CC1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)NC1(CN=[N+]=[N-])CC1,,CN(C)C=O,O,C1CCC2=NCCCN2CC1,,test
US20060229280A1,CCCC=O.Nc1cccnc1>>CCCCNc1cccnc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20100160357A1,CC(N)(CO)c1ccc2nc(O[C@@H]3CC[C@@H](C(C)(C)C)CC3)ccc2c1>>CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3cc([C@@](C)(N)CO)ccc3n2)CC1,,CO,,O=C=O,,test
US20040171620A1,CC(=O)O.[N-]=[N+]=N[C@@H]1CC[C@@H](C(N)=O)C[C@H]1O>>CC(=O)O.NC(=O)[C@@H]1CC[C@@H](N)[C@H](O)C1,[Pd],,,CO,,test
US06090839,C=CCc1cc(Oc2ccc(F)cc2)ccc1O>>CCCc1cc(Oc2ccc(F)cc2)ccc1O,[Pd],CCOC(C)=O,,,,test
US20130018052A1,BrCCBr.CC(=O)Nc1nc(-c2ccc3nccnc3c2)c(-c2cccc(C)n2)[nH]1>>CC(=O)N1CCn2c1nc(-c1cccc(C)n1)c2-c1ccc2nccnc2c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120041198A1,CC(C)c1cnn2c(Cl)nc(Cl)cc12.NCc1ccccc1>>CC(C)c1cnn2c(NCc3ccccc3)nc(Cl)cc12,,CCO,,,,test
US20020103371A1,COc1ccc(CNCC(=O)O)c(OC)c1.CSc1ccc2[nH]c(=O)oc(=O)c2c1>>COc1ccc(CN2CC(=O)Nc3ccc(SC)cc3C2=O)c(OC)c1,,Cc1ccc(C)cc1,,,,test
US20050288318A1,Cc1ccc(NN)cc1.O=C(Cl)CCBr>>Cc1ccc(N2CCC(=O)N2)cc1,,ClCCl,,C1CCC2=NCCCN2CC1,Cl,test
US20060160865A1,CCCCN.CN(C(=O)Oc1ccc(N=C=S)cn1)c1ccccc1>>CCCCNC(=S)Nc1ccc(OC(=O)N(C)c2ccccc2)nc1,,ClCCl,,,,test
US20130225553A1,CC(C)(C)OC(=O)N1CCN[C@@H](c2ccccc2)C1.COCCBr>>COCCN1CCN(C(=O)OC(C)(C)C)C[C@@H]1c1ccccc1,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US20090093463A1,NC(=O)C1CCNCC1.O=C(CCl)NC12CC3CC(C1)CC(c1ccccc1)(C3)C2>>NC(=O)C1CCN(CC(=O)NC23C[C@H]4C[C@@H](C2)CC(c2ccccc2)(C4)C3)CC1,,CS(C)=O,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US20140155415A1,COc1ccc(S(=O)(=O)Cl)cc1OC.C[C@@](O)(c1ccnc(-c2cccc3cc([C@H](N)c4ccccc4Cl)sc23)c1)C(F)(F)F>>COc1ccc(S(=O)(=O)N[C@@H](c2cc3cccc(-c4cc([C@@](C)(O)C(F)(F)F)ccn4)c3s2)c2ccccc2Cl)cc1OC,CN(C)c1ccncc1,CN(C)C=O,CO,CCN(C(C)C)C(C)C,,test
US20090226398A1,COC(=O)c1cnc(-c2ccc(OC)cc2C(F)(F)F)cn1>>COc1ccc(-c2cnc(CO)cn2)c(C(F)(F)F)c1,,C1CCOC1,O,[BH4-].[Na+],,test
US05114949,O=S1(=O)c2cccc3cccc(c23)N1CCCl.c1ccc2c(CC3CCNCC3)c[nH]c2c1>>O=S1(=O)c2cccc3cccc(c23)N1CCN1CCC(Cc2c[nH]c3ccccc23)CC1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20100024683A1,C=C(C)C(=O)Cl.CC(C)(c1ccc(N)cc1)c1ccc(O)cc1>>C=C(C)C(=O)Nc1ccc(C(C)(C)c2ccc(O)cc2)cc1,,CCOC(C)=O,,CC(=O)N(C)C,,test
US06057345,CCN(Cc1cc(Br)ccc1N)c1ccc(C(N)=O)nn1.O=Cc1ccccc1>>CCN(Cc1cc(Br)ccc1NCc1ccccc1)c1ccc(C(N)=O)nn1,,CO,,[BH3-]C#N.[Na+],,test
US04009175,O=C1c2ccccc2C(=O)N1OCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2>>NOCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2,,CCO,,NN,O,test
US20120108574A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3c(Br)nc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1.CCCC[Sn](CCCC)(CCCC)c1nccs1>>CC(C)(C)OC(=O)NC1(c2ccc(-c3c(-c4nccs4)nc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O,,test
US20110166122A1,O=[N+]([O-])c1cnc2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nn12>>Nc1cnc2ccc(N3CCC[C@@H]3c3cc(F)ccc3F)nn12,,CCO,,,,test
US04303486,O=C(O)C12CC3CC(CC(C3)C1)C2>>C1C2CC3CC1CC(C2)C3,,CC#N,,,,test
US20140213591A1,BrCC1CC1.O=C1CCCc2cc(O)ccc21>>O=C1CCCc2cc(OCC3CC3)ccc21,,CC#N,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20120202834A1,Cc1cc([N+](=O)[O-])cc(C)c1OS(=O)(=O)C(F)(F)F.FC(F)(F)c1c[nH]cn1>>Cc1cc([N+](=O)[O-])cc(C)c1-n1cnc(C(F)(F)F)c1,,CN(C)C=O,O,[H-].[Na+],,test
US20150141433A1,COC(=O)c1ccc(Br)cn1.N#C[Cu]>>COC(=O)c1ccc(C#N)cn1,,CN1CCCC1=O,,,,test
US05171354,CC(C(=O)c1ccc(Cl)cc1Cl)c1cccnc1.NO>>CC(C(=NO)c1ccc(Cl)cc1Cl)c1cccnc1,,CCO,O,Cl,c1ccncc1,test
US20040122063A1,CN1CCc2nc(C(=O)N[C@H]3C[C@H](CO[Si](c4ccccc4)(c4ccccc4)C(C)(C)C)CC[C@@H]3NC(=O)OC(C)(C)C)sc2C1>>CN1CCc2nc(C(=O)N[C@H]3C[C@H](CO)CC[C@@H]3NC(=O)OC(C)(C)C)sc2C1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090023707A1,C1CCNC1.Cn1c(C(=O)O)cnc1Br>>Cn1c(C(=O)N2CCCC2)cnc1Br,,C1CCOC1,,ClCCCl,On1nnc2ccccc21,test
US04530715,CC1(C(=O)Cn2cncn2)CC1.O=CC(Cl)(Cl)CCl>>CC1(C(=O)C(C(O)C(Cl)(Cl)CCl)n2cncn2)CC1,,C1CCOC1,,O,O=C([O-])[O-].[K+].[K+],test
US20020165274A1,CC(C)(C)NO.COCCOCOc1c(C(C)(C)C)cc(C=O)cc1C(C)(C)C>>COCCOCOc1c(C(C)(C)C)cc(C=[N+]([O-])C(C)(C)C)cc1C(C)(C)C,,c1ccccc1,,,,test
US20100010037A1,CN(C)C=O.Cc1ccc(-c2ccnc3[nH]ccc23)c(C)c1>>Cc1ccc(-c2ccnc3[nH]cc(C=O)c23)c(C)c1,,O,,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US20130065913A1,CNCCN(C)C.COC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)c2nn(CC(=O)O)c(=O)n2C1c1ccc(C#N)cc1>>COC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)c2nn(CC(=O)N(C)CCN(C)C)c(=O)n2C1c1ccc(C#N)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090099199A1,O=C(c1ccccn1)[C@H]1CCCO1>>O[C@H](c1ccccn1)C1CCCO1,,CO,,O,[BH4-].[Na+],test
US20110098324A1,CCOC(=O)CNC(=O)c1c(O)c(C(=O)OC)c(O)n(Cc2ccc(Cl)cc2Cl)c1=O.NCC1CCCCC1>>O=C(O)CNC(=O)c1c(O)c(C(=O)NCC2CCCCC2)c(O)n(Cc2ccc(Cl)cc2Cl)c1=O,,ClC(Cl)Cl,,,,test
US04294838,OO.c1ccc(Sc2cccnc2)cc1>>O=S(c1ccccc1)c1cccnc1,,CC(=O)O,,N,,test
US20130274241A1,C1COCCN1.[N-]=[N+]=Nc1ccc(C(=O)O)cc1>>[N-]=[N+]=Nc1ccc(C(=O)N2CCOCC2)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20130053364A1,CCOC(=O)c1c(CS(=O)(=O)c2ccccc2)ccc(CC)c1OC.CI>>CCOC(=O)c1c(C(C)S(=O)(=O)c2ccccc2)ccc(CC)c1OC,,CN(C)C=O,O,[H-].[Na+],[Cl-].[NH4+],test
US20030216411A1,CC(C)(C)C(=O)CBr.CCOC(=O)c1cnc(C)[nH]c1=O>>CCOC(=O)c1cnc(C)n(CC(=O)C(C)(C)C)c1=O,,COCCOC,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080194549A1,CC(C)N(C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1C=O)C(=O)OCC[Si](C)(C)C.NC1CC1>>CC(C)N(C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]1CNC1CC1)C(=O)OCC[Si](C)(C)C,,ClCCCl,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US06168838A,CCCCCCCCc1ccc2c(c1)CC(O)c1cc(CCCCCCCC)ccc1-2.CCN(CC)S(F)(F)F>>CCCCCCCCc1ccc2c(c1)CC(F)c1cc(CCCCCCCC)ccc1-2,,ClCCl,,,,test
US05114936,COC(=O)Cl.O=C1CCCc2onc(-c3ccccc3F)c21>>COC(=O)C1CCc2onc(-c3ccccc3F)c2C1=O,,C1CCOC1,CCOC(C)=O,O,CC(C)[N-]C(C)C.[Li+],test
US20010027196A1,CS(=O)c1nc(N)nc(-c2ccco2)c1Br.SCc1ccccc1>>Nc1nc(SCc2ccccc2)c(Br)c(-c2ccco2)n1,,C1COCCO1,,C1CCC2=NCCCN2CC1,,test
US20120077781A1,CCOC(=O)CCCCCCn1c2nc(=O)[nH]c(=O)c-2nc2cc(C)c(Cl)cc21.NC1CCCC1>>CCOC(=O)CCCCCCn1c2nc(=O)[nH]c(=O)c-2nc2cc(C)c(NC3CCCC3)cc21,,CN(C)C=O,,,,test
US06034055,CC(C)(C)OC(=O)NCC(=O)NCC(=O)O.CCCCCCCC/C=C\CCCCCCCC(=O)N(CCCCCCCCCCCCCCCCCC)[C@]1(N)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1C(=O)CN>>CCCCCCCC/C=C\CCCCCCCC(=O)N(CCCCCCCCCCCCCCCCCC)[C@]1(N)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1C(=O)CNC(=O)CNC(=O)CNC(=O)OC(C)(C)C,,ClCCl,,,,test
US20070105943A1,CCOC(=O)c1c[nH]oc1=O.S=C(Cl)Oc1ccccc1>>CCOC(=O)c1cn(C(=S)Oc2ccccc2)oc1=O,,Cc1ccccc1,,O,c1ccncc1,test
US20030166928A1,Fc1ccc(CCBr)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>Fc1ccc(CC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.[Br-],,Cc1ccccc1,,,,test
US20120238564A1,CC(C)(C)OC(=O)NC1CCC(Nc2nccn3c(-c4cccc(NCc5ccccc5Cl)n4)cnc23)CC1>>NC1CCC(Nc2nccn3c(-c4cccc(NCc5ccccc5Cl)n4)cnc23)CC1,,CCO,Cl,,,test
US20120094992A1,Cc1cc(C(=O)NC2CC2)ccc1N1CCN(C(=O)OC(C)(C)C)CC1>>Cc1cc(C(=O)NC2CC2)ccc1N1CCNCC1,,C1COCCO1,CCOCC,Cl,,test
US20130053345A1,CC(C)c1noc(N2CCC(Oc3nc4ccc(C5=CCNCC5)cc4s3)CC2)n1.COC(=O)CCCS(=O)(=O)Cl>>COC(=O)CCCS(=O)(=O)N1CC=C(c2ccc3nc(OC4CCN(c5nc(C(C)C)no5)CC4)sc3c2)CC1,,ClCCl,,CCN(CC)CC,,test
US06528223B1,CCCCNCCCC.COc1cccc(C(=O)Cl)c1.N#C[S-]>>CCCCN(CCCC)C(=S)NC(=O)c1cccc(OC)c1,,CC(C)=O,,Cl,,test
US04528287,CC1CNCCN1.CCn1cc(C(=O)O)c(=O)c2cc(F)c(F)c(F)c21>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c21,,c1ccncc1,,,,test
US06153609,COc1ccc(S(=O)(=O)N(CCCO[Si](C)(C)C(C)(C)C)C(C(=O)OCc2ccccc2)C2CCCCC2)cc1>>COc1ccc(S(=O)(=O)N(CCCO)C(C(=O)OCc2ccccc2)C2CCCCC2)cc1,,ClCCl,,CCOCC,FB(F)F,test
US04283403,CC=CCN=C=S.ON=C(Cl)c1ccccc1>>S=C=NCCC1CC(c2ccccc2)=NO1,,C1CCOC1,,CCN(CC)CC,CCOCC,test
US20070027178A1,O=[N+]([O-])c1cc(F)ccc1F.SCCCCl>>O=[N+]([O-])c1cc(F)ccc1SCCCCl,,C1CCOC1,,[K+].[OH-],,test
US20050009109A1,CCCCCCN(CCCCCC)c1ccc(C(=O)C(C)(C)O)s1.N#CCC#N.c1ccncc1>>CCCCCCN(CCCCCC)c1ccc(C2=C(C#N)C(=C(C#N)C#N)OC2(C)C)s1,,O,,CC(=O)O,,test
US20120309750A1,CCN.CCNC(=O)c1noc(-c2cc(C(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)c1C1CC(C(=O)OCC)=NO1>>CCNC(=O)C1=NOC(c2c(C(=O)NCC)noc2-c2cc(C(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)C1,,CO,,,,test
US20120015962A1,CCOC(=O)c1cn[nH]c1N.O=CC1=COCCC1>>CCOC(=O)c1cnn2cc(CCCO)cnc12,,CN(C)C=O,,[H-].[Na+],,test
US04088644,CCNCC(=O)c1ccccc1.O=C(Cl)OCc1ccccc1>>CCN(CC(=O)c1ccccc1)C(=O)OCc1ccccc1,,O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20040062706A1,CCN(CC)C(=O)c1ccccc1.[Li][AlH][SeH]>>CCN(CC)C(=[Se])c1ccccc1,,CCOCC,,O=C(Cl)C(=O)Cl,,test
US20140371454A1,C=CCc1cc(C(C)=O)ccc1O.OC/C=C\CO>>CC(=O)c1ccc(O)c(CC=CCO)c1,,C1CCOC1,,,,test
US20140163008A1,COCc1cn2ccccc2n1.O=C1CCC(=O)N1I>>COCc1nc2ccccn2c1I,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20010025054A1,COc1ccc(CCN(C)CCCN)cc1OC.ClCCl.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>COc1ccc(CCN(C)CCCNC(=O)c2ccc([N+](=O)[O-])cc2)cc1OC.Cl,,ClCCl,,CCN(CC)CC,,test
US20090143448A1,NS(=O)(=O)c1cc2ccccc2[nH]1.Nc1ncc(Br)s1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ncc(Br)s1)NS(=O)(=O)c1cc2ccccc2[nH]1,,CC#N,,CCN(CC)CC,,test
US20070269664A1,CC(C)[Si](Cl)(C(C)C)C(C)C.OCCc1cc(F)cc(F)c1>>CC(C)[Si](OCCc1cc(F)cc(F)c1)(C(C)C)C(C)C,,ClCCl,O,c1c[nH]cn1,,test
US05834482,CC=CN(C=CC)c1ccc2[nH]c3cnc(-c4nc(CC)no4)cc3c2c1.ClCCCBr>>CC=CN(C=CC)c1ccc2c(c1)c1cc(-c3nc(CC)no3)ncc1n2CCCCl,,CN(C)C=O,,[H-].[Na+],,test
US04742057,CC(=O)Nc1nc(CCCO)cs1.O=S(Cl)Cl>>CC(=O)Nc1nc(CCCCl)cs1,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US05616575,CC(=O)OC(C)=O.NCCc1csc2ccccc12>>NC(=O)CCCc1csc2ccccc12,,CN(C)C=O,O,CCN(CC)CC,,test
US20040259808A1,C[C@H](CS)C(=O)N1CCC[C@H]1C(=O)O.O=C(Cl)OCCl>>C[C@H](CSC(=O)OCCl)C(=O)N1CCC[C@H]1C(=O)O,,C1COCCO1,O,CCN(C(C)C)C(C)C,,test
US05424280,COC(=O)COc1ccccc1Oc1cc(F)ccc1[N+](=O)[O-].Cn1nc(O)cc1C(F)(F)F>>COC(=O)COc1ccccc1Oc1cc(Oc2cc(C(F)(F)F)n(C)n2)ccc1[N+](=O)[O-],,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20120157425A1,CC(=O)N[C@@H](C)c1ccc(C2CCNCC2)cc1.N#CBr>>CC(=O)N[C@@H](C)c1ccc(C2CCN(C#N)CC2)cc1,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,,test
US20050176964A1,Cc1cc(N)ccc1I.O=C(O)c1ccnc(Cl)c1>>Cc1ccc(NC(=O)c2ccnc(Cl)c2)cc1I,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050032820A1,CC(C)(C)OC(=O)Nc1nn(-c2ccccc2F)cc1OCc1ccccc1>>Nc1nn(-c2ccccc2F)cc1OCc1ccccc1,,CCOC(C)=O,ClC(Cl)Cl,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20130017194A1,C#C[Si](CC)(CC)CC.CCOC(=O)Cc1cncnc1Cl>>CCOC(=O)Cc1cncnc1C#C[Si](CC)(CC)CC,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040102436A1,CN(CCc1cccc(OCc2ccccc2)c1)c1cnc(-c2ccccc2)c(-c2ccccc2)n1>>CN(CCc1cccc(O)c1)c1cnc(-c2ccccc2)c(-c2ccccc2)n1,,CCO,,Cl,O=C([O-])O.[Na+],test
US20140343032A1,CC(C)(C)OC(=O)NS(=O)(=O)Cl.COC(=O)C1=C(CN2[C@H]3COC[C@@H]2CC(N)C3)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl>>COC(=O)C1=C(CN2[C@H]3COC[C@@H]2CC(NS(=O)(=O)NC(=O)OC(C)(C)C)C3)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl,,ClCCl,,CCN(CC)CC,,test
US20150232459A1,CCOC[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H](C(=O)OCC)O1>>CCOC[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H](C(=O)O)O1,,CO,,[Na+].[OH-],[Cl-].[NH4+],test
US20130217680A1,CC(C)(C)OC(=O)N1CCN(CCc2ccc3c(c2)CCOC3=O)CC1.Cl>>Cl.O=C1OCCc2cc(CCN3CCNCC3)ccc21,,C1COCCO1,,,,test
US20110183954A1,C[C@H](Nc1nc(Cl)nc(Nc2cn(C)cn2)n1)c1ncc(F)cc1F.FC1CCNCC1>>C[C@H](Nc1nc(Nc2cn(C)cn2)nc(N2CCC(F)CC2)n1)c1ncc(F)cc1F,,CCO,,CCN(C(C)C)C(C)C,,test
US05332741,BrCCCOc1cccc2c1SCCC2.COc1cccc2c1CC(N)CO2>>COc1cccc2c1CC(NCCCOc1cccc3c1SCCC3)CO2,,CN(C)C=O,,CCN(CC)CC,,test
US20090088459A1,CC(C)CN.O=Cc1ccc(Br)s1>>CC(C)CNCc1ccc(Br)s1,,CO,,[BH4-].[Na+],,test
US04997836,CI.COc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)C(CO)C2)cc(OC)c1OC>>COCC1CN(C(=O)c2cc(OC)c(OC)c(OC)c2)CCN1C(=O)OC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US04628024,CCCCCCCC(CCCC)OC(=O)N(C(=O)C(Cl)(Cl)C(=O)c1ccc(OC)cc1)c1ccccc1.O=C(O)c1cccc(-n2nnnc2S)c1>>CCCCCCCC(CCCC)OC(=O)N(C(=O)C(Cl)(Sc1nnnn1-c1cccc(C(=O)O)c1)C(=O)c1ccc(OC)cc1)c1ccccc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US05457118,Brc1cc(Br)cc(Br)c1.CCOCC.N#Cc1cccnc1>>O=C(c1cccnc1)c1cc(Br)cc(Br)c1,,CCCCCC,,Cl,[Li]CCCC,test
US20030176506A1,CC(=O)OC(C)=O.O=Cc1ccc(O)c(Cl)c1>>CC(=O)Oc1ccc(C=O)cc1Cl,,ClCCl,,c1ccncc1,,test
US20150203511A1,Cc1cc(-n2cccn2)ccc1OCc1c(C)cccc1-n1nnn(C)c1=O.O=C1CCC(=O)N1Cl>>Cc1cc(-n2cc(Cl)cn2)ccc1OCc1c(C)cccc1-n1nnn(C)c1=O,,O,,ClC(Cl)Cl,,test
US05801271,CCOC(=O)C(C(=O)CCCCNC(=O)OCc1ccccc1)c1ccccc1>>CCOC(=O)C(c1ccccc1)C(O)CCCCNC(=O)OCc1ccccc1,,CO,,,,test
US20090197863A1,COC(=O)c1ccc(-c2ccccn2)cc1F>>O=C(O)c1ccc(-c2ccccn2)cc1F,,C1CCOC1,O,CO,[Li+].[OH-],test
US20030187040A1,N[C@@H](C(=O)O)c1ccccc1.[NH4+]>>NC(=O)[C@H](N)c1ccccc1,,C1COCCO1,,Cl,O,test
US20100256144A1,CC[Si](C#Cc1ccc2cccc(CNC(=O)N3CCC[C@H]3C(=O)O)c2c1)(CC)CC>>C#Cc1ccc2cccc(CNC(=O)N3CCC[C@H]3C(=O)O)c2c1,,C1CCOC1,,,,test
US20130203748A1,CCOC(=O)c1cc2nc(C)c([C@H](OC(C)(C)C)C(=O)OCC)c(-c3ccc4c(c3Cl)NCCO4)n2n1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc(C(=O)O)nn2c1-c1ccc2c(c1Cl)NCCO2,,CCO,,[Na+].[OH-],,test
US05015661,Cc1c(C)c2c(c(C)c1O)CCC(C)(C#Cc1ccc(OCc3ccccc3)c(O)c1)O2>>Cc1c(C)c2c(c(C)c1O)CCC(C)(CCc1ccc(O)c(O)c1)O2,[Pd],CC(=O)O,,CCO,,test
US20150232481A1,C#Cc1ccccc1CO.C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(CN=[N+]=[N-])nn23)CC1>>C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(Cn4cc(-c5ccccc5CO)nn4)nn23)CC1,[Cu]I,C1CCOC1,CCOCC,CCN(C(C)C)C(C)C,,test
US20110086889A1,COc1ccc(Cn2nccc2NC(=O)CBr)cc1.Fc1cccc(-n2nnnc2S)c1>>COc1ccc(Cn2nccc2NC(=O)CSc2nnnn2-c2cccc(F)c2)cc1,,CN(C)C=O,,c1ccncc1,,test
US06235789B1,COc1ccc(N=C=O)cc1.COc1ccc2c(c1)C(=CCN)CCC2>>COc1ccc(NC(=O)NC/C=C2\CCCc3ccc(OC)cc32)cc1,,C1CCOC1,,O,,test
US20120142732A1,CC(=O)Nc1cc(-c2cc(-c3ncn(COCC[Si](C)(C)C)n3)c(-c3cc(CN4CCCC4)ccc3Cl)o2)c(C)cn1>>CC(=O)Nc1cc(-c2cc(-c3nnc[nH]3)c(-c3cc(CN4CCCC4)ccc3Cl)o2)c(C)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050032829A1,CCCCc1nc2c(c(C)c(C)n3nnnc23)n1CC(C)(C)N.O=C=NC1CCCCC1>>CCCCc1nc2c(c(C)c(C)n3nnnc23)n1CC(C)(C)NC(=O)NC1CCCCC1,,ClCCl,,,,test
US20120220572A1,CC(C)(C)OC(=O)N1Cc2cc(N)ccc2C2(CC2)C1.CSc1ncc2c(=O)n(-c3c(Cl)cc(F)cc3Cl)c3nccn3c2n1>>CC(C)(C)OC(=O)N1Cc2cc(Nc3cn4c(=O)n(-c5c(Cl)cc(F)cc5Cl)c5ncncc5c4n3)ccc2C2(CC2)C1,,CCOC(C)=O,ClCCl,O=C(OO)c1cccc(Cl)c1,,test
US20050032846A1,CCC(N)CC.Cc1cc(C)c(Nc2nc(C)nc(Cl)c2[N+](=O)[O-])c(C)n1>>CCC(CC)Nc1nc(C)nc(Nc2c(C)cc(C)nc2C)c1[N+](=O)[O-],,C1CCOC1,,,,test
US20060100203A1,CCOC(=O)c1nnc(SC)nc1NC(=O)Cc1c(F)cccc1Cl>>CSc1nnc2c(n1)NC(=O)C(c1c(F)cccc1Cl)C2=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090005418A1,COc1ccc(CN2OC(c3cc(Cl)ccc3F)=CC2(C)c2ccccc2)c(OC)c1>>CC1(c2ccccc2)C=C(c2cc(Cl)ccc2F)ON1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],test
US20070142452A1,CCOC(=O)c1cc2ccccc2[nH]1.O=C(Cl)c1cccc2ccccc12>>CCOC(=O)c1[nH]c2ccccc2c1C(=O)c1cccc2ccccc12,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US04227011,C#CCBr.CCCCC(=O)CCl>>C#CCC(O)(CCl)CCCC,,CCOCC,,[Mg],[Cl-].[NH4+],test
US04442115,CCCC[Sn](CCCC)(CCCC)N=[N+]=[N-].CCOC(=O)C#N>>CCOC(=O)c1nnn[nH]1,,c1ccccc1,,,,test
US20060111370A1,C=CCI.CC1(c2cccc(Br)c2)COS(=O)(=O)N1>>C=CCN1C(C)(c2cccc(Br)c2)COS1(=O)=O,,ClCCl,,[Na+].[OH-],,test
US20130150368A1,C=CB1OB(C=C)OB(C=C)O1.CC(C)(CNc1ncc(Br)cn1)c1ccc(F)cc1>>C=Cc1ccc(NCC(C)(C)c2ccc(F)cc2)nc1,,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20160096827A1,COc1ccc(B2OC(C)(C)C(C)(C)O2)cc1C#N.Clc1ncnc(Nc2ccc(N3CCN(C4COC4)CC3)cc2)n1>>COc1ccc(-c2ncnc(Nc3ccc(N4CCN(C5COC5)CC4)cc3)n2)cc1C#N,,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20100210524A1,COCN(Cc1ccccc1)C[Si](C)(C)C.COc1ccc(C(=O)/C=C/C(C)=O)cc1>>COc1ccc(C(=O)C2CN(Cc3ccccc3)CC2C(C)=O)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110039852A1,CCOC(=O)Cc1ccc(OCc2ccccc2)c(-c2ccc(C(F)(F)F)cc2CN(CC)C(=O)OCc2ccccc2)c1>>CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OCc1ccccc1)C(=O)OCc1ccccc1,,CO,,Cl,[Li+].[OH-],test
US20020022643A1,C=CCOCc1ccccc1.CCOC(=O)C=[N+]=[N-]>>CCOC(=O)C1CC1COCc1ccccc1,,CCOCC,,,,test
US20120115899A1,COC(OC)c1cnc(C)c(Br)c1.O=C(OO)c1cccc(Cl)c1>>COC(OC)c1cc(Br)c(C)[n+]([O-])c1,,ClCCl,,[Na+].[OH-],,test
US04061641,CNC1CCN(CCc2c[nH]c3ccccc23)CC1.S=C=Nc1ccccc1>>CN(C(=S)Nc1ccccc1)C1CCN(CCc2c[nH]c3ccccc23)CC1,,c1ccccc1,,,,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2c(OC)cccc23)cc1.Nc1ccc(N2CCOCC2)c(F)c1>>COc1cccc2c1nc(Nc1ccc(N3CCOCC3)c(F)c1)c1n[nH]cc12,C1COCCO1,CO,,Cl,,test
US20100305096A1,CS(=O)(=O)N1C[C@@H]2C[C@H]1CN2.Cn1c(C=O)nc2c(N3CCOCC3)nc(Cl)nc21>>Cn1c(CN2C[C@@H]3C[C@H]2CN3S(C)(=O)=O)nc2c(N3CCOCC3)nc(Cl)nc21,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100240661A1,CC1=C(Br)C(=O)OC1=O.COc1ccc(CN)c(OC)c1>>COc1ccc(CN2C(=O)C(C)=C(Br)C2=O)c(OC)c1,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20080146566A1,CCNC(=O)c1ccc(C)c(-n2ccc3ccc(O)cc3c2=O)c1.CCOC(C)=O.ClCCBr>>Cc1ccc(C(=O)NC2CC2)cc1-n1ccc2ccc(OCCCl)cc2c1=O,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100173901A1,CC1Cc2ccc(C3=CCN(C(=O)OC(C)(C)C)CC3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1>>CC1Cc2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1,[Pd],CO,,[H][H],,test
US20070066639A1,CC(=O)OCCCn1cnc2cnc3cccnc3c21>>OCCCn1cnc2cnc3cccnc3c21,,CO,,O=C([O-])[O-].[K+].[K+],,test
US06294503B1,Cn1c(C(F)(F)F)cc(=O)n(-c2cc3c(cc2F)OCC(=O)N3)c1=O.O=[N+]([O-])O>>Cn1c(C(F)(F)F)cc(=O)n(-c2c(F)cc3c(c2[N+](=O)[O-])NC(=O)CO3)c1=O,,CC(=O)O,,,,test
US20080188528A1,COC(=O)[C@H](CCCNC(=O)OC(C)(C)C)NC(=O)c1cccn(Cc2cc(Cl)cc(Cl)c2)c1=O>>CC(C)(C)OC(=O)NCCC[C@H](NC(=O)c1cccn(Cc2cc(Cl)cc(Cl)c2)c1=O)C(=O)O,,CO,,C1CCOC1,[Na+].[OH-],test
US20130109649A1,O=C(Cl)Cl.O[C@H](c1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@@H]1CCC[C@@H](c2cc(C(F)(F)F)ccc2Br)N1>>Cc1cc([C@H]2OC(=O)N3[C@H](c4cc(C(F)(F)F)ccc4Br)CCC[C@@H]23)cc(C(F)(F)F)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20030153596A1,CC(C)(C)C(N=C=S)c1ccccc1.Cn1cc([N+](=O)[O-])cc1CO>>Cn1cc([N+](=O)[O-])cc1COC(=S)NCc1ccc(C(C)(C)C)cc1,,C1CCOC1,,[H-].[Na+],,test
US20050038035A1,COC(=O)c1cc(C(C)=O)ccc1-c1ccc(C(F)(F)F)cc1>>CC(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)c(C(=O)O)c1,,CCO,O,[Na+].[OH-],,test
US04181802,ClCc1cccnc1.Cn1c(=O)[nH]c2ccccc21>>Cn1c(=O)n(Cc2cccnc2)c2ccccc21,,CO,,Cl,C[O-].[Na+],test
US20080004309A1,CCOC(=O)c1nc(C#N)c2c(ccn2Cc2ccc(F)c(F)c2)c1OC(C)=O.O=C1CCC(=O)N1Cl>>CCOC(=O)c1nc(C#N)c2c(c(Cl)cn2Cc2ccc(F)c(F)c2)c1OC(C)=O,,CC#N,,,,test
US05665733,CNC.Cn1c(-c2ccccc2)c(CCC(=O)O)c2ccccc2c1=O>>CN(C)C(=O)CCc1c(-c2ccccc2)n(C)c(=O)c2ccccc12,,ClCCl,,,,test
US05623081,COP([O-])OC.O=CC(=O)OCc1ccc([N+](=O)[O-])cc1>>COP(=O)(OC)C(O)C(=O)OCc1ccc([N+](=O)[O-])cc1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04622342,COc1ccc(C=C(C)[N+](=O)[O-])cc1F>>COc1ccc(CC(C)=O)cc1F,[Fe],,,C1CCOC1,Cl,test
US20160175289A1,C[C@@H]1Cc2c([nH]c3ccc(F)cc23)[C@@H](c2c(F)cc(NC3CN(CCCF)C3)cc2F)N1CC(C)(F)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C>>CC1Cc2c([nH]c3ccc(F)cc23)C(c2c(F)cc(NC3CN(CCCF)C3)cc2F)N1CC(C)(F)CO,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20070185143A1,CCOC(=O)C(=O)C1CCC=C(OCC)C1=O.CNN>>CCOC(=O)c1nn(C)c2c1CCCC2=O,,CC(=O)O,,,,test
US20140243288A1,O.O=C1NCC(CO)O1.O=C1O[C@@H](CO)CN1c1ccc(-c2ccc3c(c2)CN(c2cnn[nH]2)C3)c(F)c1.O=P(Cl)(Cl)Cl>>O=C1O[C@@H](COP(=O)(O)O)CN1c1ccc(-c2ccc3c(c2)CN(c2cnn[nH]2)C3)c(F)c1,,C1CCOC1,,CCN(CC)CC,,test
US20160218303A1,N#Cc1cccc([N+](=O)[O-])c1F.Nc1ccccc1>>N#Cc1cccc([N+](=O)[O-])c1Nc1ccccc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20030166650A1,CC(NC(=O)C=Cc1ccccc1F)c1ccc2c(c1)NCCC2.O=CO>>CC(NC(=O)C=Cc1ccccc1F)c1ccc2c(c1)N(C)CCC2,,O=CO,,CO,[BH4-].[Na+],test
US20110059948A1,CCOC(=O)c1c(Cl)nc2ccc(Br)cc2c1Cl.NCc1ccccc1>>CCOC(=O)c1c(NCc2ccccc2)nc2ccc(Br)cc2c1Cl,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US04710510,CC1(C)C(=O)Nc2cc(NC(=O)c3ccccc3)c([N+](=O)[O-])cc21>>CC1(C)C(=O)Nc2cc3[nH]c(-c4ccccc4)nc3cc21,[Pd],CC(=O)O,,[H][H],,test
US08003626B2,CCOC(=O)C1CN(C)N=C1C(F)(F)F>>CN1CC(C(=O)O)C(C(F)(F)F)=N1,,C1COCCO1,,Cl,[Na+].[OH-],test
US04550105,COc1ccc(CN2C(=O)[C@@H](N3C(=O)c4ccccc4C3=O)[C@H]2/C=C/c2ccccc2)c(OC)c1>>COc1ccc(CN2C(=O)[C@@H](N3C(=O)c4ccccc4C3=O)[C@H]2CCc2ccccc2)c(OC)c1,[Pd],C1CCOC1,,[H][H],,test
US20140309193A1,CCOC(=O)c1c(OC(=O)C(C)(C)COCCCOP(=O)(OCc2ccccc2)OCc2ccccc2)c(OC(=O)C(C)(C)COCCCOP(=O)(OCc2ccccc2)OCc2ccccc2)c(C(=O)N(C)C)n1-c1ccc(OC)cc1>>CCOC(=O)c1c(OC(=O)C(C)(C)COCCCOP(=O)(O)O)c(OC(=O)C(C)(C)COCCCOP(=O)(O)O)c(C(=O)N(C)C)n1-c1ccc(OC)cc1,[Pd],CO,,,,test
US05521197,Fc1ccc2[nH]ccc2c1.O=C1CCNCC1>>Fc1ccc2[nH]cc(C3=CCNCC3)c2c1,,CO,O,Cl,[K+].[OH-],test
US20050020654A1,CCCC(=O)Nc1c(C)cc(Br)cc1N>>CCCc1nc2c(C)cc(Br)cc2[nH]1,,CC(=O)O,,,,test
US20120071467A1,CI.Cc1cc(NC(=O)OC(C)(C)C)sc1C(=O)N(C)CCN(C)C(=O)OC(C)(C)C>>Cc1cc(CNC(=O)OC(C)(C)C)sc1C(=O)N(C)CCN(C)C(=O)OC(C)(C)C,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20150225342A1,O=C(CN1CC2CC(c3ccccc3)CC2C1)c1ccc(O)cc1>>Oc1ccc(C(O)CN2CC3CC(c4ccccc4)CC3C2)cc1,,CCO,,[BH4-].[Na+],,test
US20010027196A1,CS(=O)c1nc(N)nc(-c2ccco2)c1C#N.Cc1cccc(CO)n1>>Cc1cccc(COc2nc(N)nc(-c3ccco3)c2C#N)n1,,COCCOC,,C1CCC2=NCCCN2CC1,,test
US20080200448A1,CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)OC(C)(C)C)CC2)nc1CN1CCCC1=O>>CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)O)CC2)nc1CN1CCCC1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130172341A1,CC(C)(C)OC(=O)N1CCc2[nH]nc(-c3ccncc3)c2C1.Cl>>Cl.c1cc(-c2n[nH]c3c2CNCC3)ccn1,,C1COCCO1,,,,test
US20110178056A1,CC(C)Oc1ccc(C(=O)O)cc1C#N.N=C(NO)c1cccc2c1CCC[C@H]2O>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC[C@H]4O)no2)cc1C#N,,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20090023702A1,FC(F)(F)/C=C/Br.OB(O)c1ccc(OCc2ccccc2)cc1>>FC(F)(F)/C=C/c1ccc(OCc2ccccc2)cc1,,CCOC(C)=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US03952008,CCOC(=O)C(=C(N)OCC)c1ccccc1.Cc1ccc(CNN)cc1C(F)(F)F>>Cc1ccc(Cn2[nH]c(N)c(-c3ccccc3)c2=O)cc1C(F)(F)F,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20150301368A1,CCCC1CCC(C2CCC(CCBr)CC2)CC1.OC(COCc1ccccc1)COCc1ccccc1>>CCCC1CCC(C2CCC(CCOC(COCc3ccccc3)COCc3ccccc3)CC2)CC1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20100286148A1,CC[Si](CC)(CC)OC(c1ccncc1)C(F)(F)F.O=C(OO)c1cccc(Cl)c1>>CC[Si](CC)(CC)OC(c1cc[n+]([O-])cc1)C(F)(F)F,,ClC(Cl)Cl,,O=S([O-])[O-].[Na+].[Na+],,test
US20080269211A1,CCOC(=O)C[C@H]1CC[C@@H](N)CN1Cc1ccccc1>>N[C@@H]1CC[C@H](CCO)N(Cc2ccccc2)C1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20010051620A1,COc1ccc2cc3c(=O)c(C#N)c[nH]c3cc2c1.O=P(Cl)(Cl)Cl>>COc1ccc2cc3c(Cl)c(C#N)cnc3cc2c1,CN(C)C=O,,,,,test
US20120245026A1,CCOC(=O)Cl.Cc1cc(C)c(C2C(=O)NC3(CCN(N(C)C)CC3)C2=O)c(C)c1>>CCOC(=O)OC1=C(c2c(C)cc(C)cc2C)C(=O)NC12CCN(N(C)C)CC2,,C1CCOC1,,CCN(CC)CC,O,test
US20090221607A1,CC(C)(C)OC(=O)N1CCN(CCOc2ccc(F)cc2)CC1>>Fc1ccccc1OCCN1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04810699,Cc1ccc(Cl)c([N+](=O)[O-])c1.OCC(F)(F)F>>Cc1ccc(OCC(F)(F)F)c([N+](=O)[O-])c1,,CN(C)C=O,,[H-].[Na+],,test
US20140323464A1,CC(C)(C)OC(=O)N1CCCC(Nc2nc(Nc3ccc(N4CCOCC4)nc3)ncc2F)C1>>Fc1cnc(Nc2ccc(N3CCOCC3)nc2)nc1NC1CCCNC1,,CO,Cl,,,test
US20090022670A1,Cc1nc(C(=O)O)c(-c2ccccc2)s1.Clc1c(C[C@@H]2CCCCN2)nc2ccccn12>>Cc1nc(C(=O)N2CCCC[C@H]2Cc2nc3ccccn3c2Cl)c(-c2ccccc2)s1,,ClCCl,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US05051413,CCOC(=O)C(NC=O)/C(C)=C/CP(=O)(OCC)OCC>>C/C(=C\CP(=O)(O)O)C(N)C(=O)O,,Cl,,,,test
US20080188528A1,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2.O=C(O)c1cccn(Cc2cccc(Br)c2)c1=O>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)c2cccn(Cc3cccc(Br)c3)c2=O)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050070539A1,CC(C)(C)OC(=O)N1CCNCC1.FC(F)(F)c1ncc(Cl)cn1>>CC(C)(C)OC(=O)N1CCN(c2cnc(C(F)(F)F)nc2)CC1,,CC(=O)N(C)C,,,,test
US20080242698A1,NCc1ccc(Cl)c(Cl)c1.O=C(CCl)N(c1ccccc1)c1ccccc1>>Cl.O=C(CNCc1ccc(Cl)c(Cl)c1)N(c1ccccc1)c1ccccc1,,CCO,,,,test
US06177423B1,O=C1CCC(=O)N1Cl.O=C1c2ccc(N3CCCC3)c3cc(Br)cc(c23)C(=O)N1O>>O=C1NC(=O)c2cc(Cl)c(N3CCCC3)c3cc(Br)cc1c23,,CC(=O)O,,O,,test
US20030212094A1,Brc1ccco1.O=Cc1ccccc1OB(O)O>>O=Cc1ccccc1-c1ccco1,,CO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20080176884A1,C(=Cc1ccccc1)CO[C@@]12CCC[C@@H]3Oc4c(OCc5ccccc5)ccc5c4[C@@]31CCN(CC1CC1)[C@@H]2C5.COS(=O)(=O)C(F)(F)F>>COS(=O)(=O)C(F)(F)F.O[C@@]12CCC[C@@H]3Oc4c(OCc5ccccc5)ccc5c4[C@@]31CCN(CC1CC1)[C@@H]2C5,,ClCCl,,,,test
US20060004084A1,CO.COC=Cc1ccc2c(c1)C(C)(C)OC2=O>>COC(Cc1ccc2c(c1)C(C)(C)OC2=O)OC,O=S(=O)(O)O,CCOC(C)=O,,,,test
US20110257208A1,CC(C)(C)OC(=O)N1CC(N)=C(C#N)C1.N=CN>>CC(C)(C)OC(=O)N1Cc2ncnc(N)c2C1,,CCCCO,,CC(=O)O,,test
US05688795,O=C(Cl)c1cccnc1Cl.[Li]C(C)(C)C>>CC(C)(C)C(=O)c1cccnc1Cl,[Cu]I,C1CCOC1,,,,test
US20160039834A1,C[C@H]1C[C@@H](N=[N+]=[N-])CCN1C(=O)OC(C)(C)C>>C[C@H]1C[C@@H](N)CCN1C(=O)OC(C)(C)C,[Pd],CO,,,,test
US20130217680A1,Cc1cccc(N)n1.O=C1CCC(=O)N1Cl>>Cc1nc(N)ccc1Cl,,CN(C)C=O,,,,test
US20050038035A1,Cc1ccc(C(=O)Nc2ccc(N(CCc3csc(NC(=O)OC(C)(C)C)n3)C(=O)OC(C)(C)C)cc2)c(-c2ccc(C(F)(F)F)cc2)c1>>Cc1ccc(C(=O)Nc2ccc(NCCc3csc(N)n3)cc2)c(-c2ccc(C(F)(F)F)cc2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04145432,CCOC(=O)C1=C(C)NC(CO)=C(C(=O)OCC)C1c1ccccc1[N+](=O)[O-].O=C(Cl)COc1ccc(Cl)cc1>>CCOC(=O)C1=C(C)NC(COC(=O)COc2ccc(Cl)cc2)=C(C(=O)OCC)C1c1ccccc1[N+](=O)[O-],,ClCCl,c1ccncc1,O,,test
US20100179150A1,CCOC(=O)c1cc(Br)c(C)[nH]1.O=C1CCC(=O)N1Cl>>CCOC(=O)c1[nH]c(C)c(Br)c1Cl,,CN(C)C=O,,[Na+].[OH-],,test
US20100137587A1,CCOC(=O)C(=O)C(Br)CCc1ccccc1.Nc1ccccn1>>CCOC(=O)C(=O)C(CCc1ccccc1)[n+]1ccccc1N.[Br-],,C1CCOC1,,,,test
US20050014765A1,COc1cc(OC)cc(N2CCN(C(=O)c3cn(CCO[Si](C)(C)C(C)(C)C)cc3-c3ccccc3)CC2)c1>>COc1cc(OC)cc(N2CCN(C(=O)c3cn(CCO)cc3-c3ccccc3)CC2)c1,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20020192594A1,C=CC(=O)Cl.OCC(Br)(Br)Br>>C=CC(=O)OCC(Br)(Br)Br,,CCOCC,,CCN(CC)CC,O,test
US20140171408A1,C[Si](C)(C)Br.N#Cc1cc(F)c(-c2nc3ccnc(Cl)c3s2)c(Cl)c1>>N#Cc1cc(F)c(-c2nc3ccnc(Br)c3s2)c(Cl)c1,,CCC#N,,,,test
US20030181433A1,CCCCCCCCCCCCOC(=O)Cl.CN1CCCC1=O.NNc1ccc(OC(F)(F)F)cc1>>CCCCCCCCCCCCOc1nn(-c2ccc(OC(F)(F)F)cc2)c(=O)o1,,c1ccncc1,,,,test
US20060173004A1,COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.COCCOc1cc(C=O)c([N+](=O)[O-])cc1Cl>>COCCOc1cc(/C=C/C(=O)OC)c([N+](=O)[O-])cc1Cl,,Cc1ccccc1,,,,test
US20090325925A1,N#Cc1c(N2CCOCC2)sc(C(=O)O)c1-c1ccc(Cl)cc1Cl.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>N#Cc1c(N2CCOCC2)sc(C(=O)N=[N+]=[N-])c1-c1ccc(Cl)cc1Cl,,C1CCOC1,,,,test
US20080076763A1,C1CCOC1.CCOC(=O)N=NC(=O)OCC.CCn1c(-c2nonc2N)nc2c(Cl)ncc(O)c21.ClCCl>>CCn1c(-c2nonc2N)nc2c(Cl)ncc(OC[C@H]3CCCN(C)C3)c21,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090042967A1,CC(C)(C)[Si](C)(C)Cl.C[C@@H](CO)Nc1cccc(Cl)c1>>C[C@@H](CO[Si](C)(C)C(C)(C)C)Nc1cccc(Cl)c1,,CN(C)C=O,,O,c1c[nH]cn1,test
US06124381,CC#N.CCN(CC)CC.Clc1nc(Cl)nc(Cl)n1.N.NC1CCCCC1>>Nc1nc(NC2CCCCC2)nc(NC2CCCCC2)n1,,CC#N,O,,,test
US20090093462A1,CC1(C)OCC(CON)O1.O=C(O)c1cc(Br)ncc1Nc1ccc(I)cc1F>>CC1(C)OC[C@H](CONC(=O)c2cc(Br)ncc2Nc2ccc(I)cc2F)O1,,CN(C)C=O,,O,O=C(n1ccnc1)n1ccnc1,test
US20090197907A1,CC(C)(C#N)N=NC(C)(C)C#N.Cc1cncc(C)c1.NC(=O)CCC(=O)NBr>>CN(C)c1ccccn1,,ClC(Cl)(Cl)Cl,,,,test
US20150284396A1,CCCCc1nc(N)c2c(n1)c(C#CCCCCN1CCCCC1)cn2COCC[Si](C)(C)C>>CCCCc1nc(N)c2c(n1)c(CCCCCCN1CCCCC1)cn2COCC[Si](C)(C)C,[Pd],CC(=O)O,CCO,,,test
US20110046127A1,N#Cc1cnc2ccc(Cl)nn12.NCc1ccc(Cl)c(Cl)c1>>N#Cc1cnc2ccc(NCc3ccc(Cl)c(Cl)c3)nn12,,C1COCCO1,,,,test
US20100093724A1,CNS(C)(=O)=O.N#Cc1ccnc(Cl)n1>>CN(c1nccc(C#N)n1)S(C)(=O)=O,,C1CCOC1,O,[H-].[Na+],,test
US20100204272A1,CCO[C@@H]1CC[C@@H](N2CCC(=O)CC2)CC1.Cc1ccc(O)c(N)c1>>CCO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C)ccc3O)CC2)CC1,,ClCCl,,CC(=O)O,[BH3-]C#N.[Na+],test
US04684639,O=C(O)C(O)c1ccc(O)c(O)c1.O=S(=O)(Cl)Cl>>O=C(O)C(O)c1cc(O)c(O)cc1Cl,,CC(=O)O,,O,,test
US20090131472A1,CI.O=c1ccn2c(-c3ccc(F)cc3F)c(CO)ccc2c1-c1c(F)cccc1F>>COCc1ccc2c(-c3c(F)cccc3F)c(=O)ccn2c1-c1ccc(F)cc1F,,C1CCOC1,,[H-].[Na+],,test
US20100056639A1,Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1ccc(C#N)c(N)c1F.O=C(Cl)c1ccccc1>>Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1ccc(C#N)c(NC(=O)c2ccccc2)c1F,,C1CCOC1,,c1ccncc1,,test
US20080038213A1,CC1(C)OCC(CO)O1.CN(C)c1ccc(C(=O)Cl)cc1>>CN(C)c1ccc(C(=O)OCC2COC(C)(C)O2)cc1,,O,,c1ccncc1,,test
US20140364412A1,CC(C)[Si](Oc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc([C@@H]5CCCN5C)n4c3)c3ccccc32)cc1Cl)(C(C)C)C(C)C>>CN1CCC[C@H]1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)C)nn4-c4ccc(O)c(Cl)c4)c4ccccc43)cn12,,C1CCOC1,,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20030055085A1,O=C(Cl)C(=O)Cl.O=C(O)c1cccc(Oc2ccccc2)c1>>O=C(Cl)c1cccc(Oc2ccccc2)c1,,CN(C)C=O,,,,test
US20130338159A1,Cc1nc(N)ncc1-c1ccnc(S(C)=O)n1.Nc1ccncc1>>Cc1nc(N)ncc1-c1ccnc(Nc2ccncc2)n1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20020183319A1,C1CCNCC1.Cc1cc(C(=O)N2CCOCC2)[nH]c1C=O.O=C1Cc2c(Cl)ncnc2N1>>Cc1cc(C(=O)N2CCOCC2)[nH]c1C=C1C(=O)Nc2ncnc(N3CCCCC3)c21,C1CCNCC1,,,CCO,,test
US20080064718A1,CC(C)(C)OC(=O)N1CC=C(c2cc3nccc(Oc4ccc(NC(=O)NNC(=O)c5ccccc5)cc4F)c3s2)CC1>>O=C(NNC(=O)c1ccccc1)Nc1ccc(Oc2ccnc3cc(C4=CCNCC4)sc23)c(F)c1,,O=C(O)C(F)(F)F,,,,test
US20120329649A1,O=C1c2ccccc2C(=O)N1Cc1ccc(/C=C/C(c2cc(Cl)c(Cl)c(Cl)c2)C(F)(F)F)c2ccccc12>>NCc1ccc(/C=C/C(c2cc(Cl)c(Cl)c(Cl)c2)C(F)(F)F)c2ccccc12,,CCO,,NN,O,test
US20110172442A1,N#Cc1cccc(C=CC(=O)O)c1.O=C1CCC(=O)N1O>>N#Cc1cccc(C=CC(=O)ON2C(=O)CCC2=O)c1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20130085161A1,CC(=O)Cl.CC(=O)Nc1ccc(C)cc1N1CCC(n2c(=N)n(Cc3cccc4c3ccn4C(=O)OC(C)(C)C)c3ccccc32)CC1>>CC(=O)N=c1n(Cc2cccc3[nH]ccc23)c2ccccc2n1C1CCN(c2cc(C)ccc2NC(C)=O)CC1,,CCOC(C)=O,,CO,,test
US20120046289A1,C1CCNC1.COc1ccc(CNC(=O)c2cc(-c3cc(C)cc(C)c3)nnc2Cl)cc1OC>>COc1ccc(CNC(=O)c2cc(-c3cc(C)cc(C)c3)nnc2N2CCCC2)cc1OC,,C1COCCO1,,,,test
US20130225620A1,c1cc(Nc2cc(C3CC3)[nH]n2)nc(NCc2ccc3c(c2)ncn3C2CCCCO2)n1>>Nc1nccc(Nc2cc(C3CC3)[nH]n2)n1,,CO,O,Cc1ccc(S(=O)(=O)O)cc1,,test
US04426530,CCOC(=O)Cc1ccc([N+](=O)[O-])cc1.CCc1nn(-c2ccc(C=O)c(O)c2)nc1C>>CCc1nn(-c2ccc3cc(-c4ccc([N+](=O)[O-])cc4)c(=O)oc3c2)nc1C,,CCO,,C1CCNCC1,CC(=O)O,test
US20020007070A1,CC(C)(C)OC(=O)CBr.CC(C)c1ccc(NC(=O)OCc2ccccc2)c(=O)[nH]1>>CC(C)c1ccc(NC(=O)OCc2ccccc2)c(=O)n1CC(=O)OC(C)(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US04145432,CCOCCOC(=O)C1=C(C)NC(C=O)=C(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1>>CCOCCOC(=O)C1=C(C)NC(CO)=C(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1,,CCO,,Cl,[BH4-].[Na+],test
US05665737,COc1ccc(CC(=O)O)cc1OC1CCCC1.Nc1c(O)cccc1O>>COc1ccc(CC(=O)Nc2c(O)cccc2O)cc1OC1CCCC1,,ClCCl,O,O=C(n1ccnc1)n1ccnc1,,test
US20100256127A1,N#Cc1ccc(Cl)nc1.OCc1c(-c2ccccn2)noc1/C=C/c1ccccc1>>N#Cc1ccc(OCc2c(-c3ccccn3)noc2/C=C/c2ccccc2)nc1,,CN(C)C=O,,[H-].[Na+],,test
US20100137587A1,COCCCCn1c(C(=O)N(CC(C)C)[C@H]2C[C@@H](C(=O)O)CN(C(=O)OC(C)(C)C)C2)nc2ccccc21.Cc1nnn[nH]1>>COCCCCn1c(C(=O)N(CC(C)C)[C@H]2C[C@@H](c3nnc(C)o3)CN(C(=O)OC(C)(C)C)C2)nc2ccccc21,,CCOC(C)=O,Cc1ccccc1,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20040198778A1,COC(=O)C(NS(=O)(=O)c1ccc(Cl)s1)C(CC(F)(F)F)CC(F)(F)F>>O=S(=O)(NC(CO)C(CC(F)(F)F)CC(F)(F)F)c1ccc(Cl)s1,,C1CCOC1,,[BH4-].[Li+],,test
US20100267634A1,CC(C)(C)OC(=O)[C@@H](NC(=O)O[C@H]1CCOC1)C(C)(C)C>>CC(C)(C)[C@H](NC(=O)O[C@H]1CCOC1)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020091148A1,CN(NC(=O)OCc1ccccc1)C(=O)c1[nH]c2ccccc2c1-c1ccccc1>>CN(N)C(=O)c1[nH]c2ccccc2c1-c1ccccc1,[Pd],C1CCOC1,CO,,,test
US20080113987A1,CC(=O)Cl.FC(F)c1nc2ccccc2n1-c1nc(N2CCNCC2)nc(N2CCOCC2)n1>>CC(=O)N1CCN(c2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)CC1,,O,,C1CCOC1,,test
US20080103123A1,CC(C)(C)OC(=O)N1CCC(NCc2ccc(Cl)nc2)CC1.CCOC1(O[Si](C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(N(Cc2ccc(Cl)nc2)C2CC2)CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20090306161A1,COc1c(Br)cccc1CO.[N-]=[N+]=NP(=O)(Oc1ccccc1)Oc1ccccc1>>COc1c(Br)cccc1CN=[N+]=[N-],,Cc1ccccc1,,C1CCC2=NCCCN2CC1,,test
US20090209556A1,CCOC=C(C(=O)OCC)C(=O)C(F)(F)F.NNc1ccnc(Cl)n1>>CCOC(=O)c1cnn(-c2ccnc(Cl)n2)c1C(F)(F)F,,CC#N,,CCN(CC)CC,,test
US20060063820A1,CC(C)OC(=O)N=NC(=O)OC(C)C.Cc1ccccc1.OCc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl.Oc1ccnc(C(F)(F)F)c1>>FC(F)(F)c1cc(OCCOCc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)ccn1,,Cc1ccccc1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20130225524A1,CCOC(=O)c1cnc2cc(-c3c(C)noc3C)ccc2c1O.O=S(Cl)Cl>>Cc1noc(C)c1-c1ccc2c(Cl)c(C(=O)O)cnc2c1,,CCOCC,,CCO,[Na+].[OH-],test
US05679671,O=C1CCCc2ccc(O)cc21.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=C1CCCc2ccc(OS(=O)(=O)C(F)(F)F)cc21,,ClCCl,,O,c1ccncc1,test
US20130150339A1,COc1ccc(Cl)c(-c2cccc(F)c2)c1.O=C1CCC(=O)N1I>>COc1cc(-c2cccc(F)c2)c(Cl)cc1I,,ClCCl,,CC(=O)O,O=S(=O)(O)O,test
US20110257151A1,COC(=O)c1ccc2c(c1)CC(C)(C)C(c1ccccc1NS(=O)(=O)c1ccc(F)cc1)N2>>CC1(C)Cc2cc(C(=O)O)ccc2NC1c1ccccc1NS(=O)(=O)c1ccc(F)cc1,,C1CCOC1,,[Na+].[OH-],,test
US04179465,Cc1cc(O)cc(C(C)C)c1.O=C(F)N(CF)CF>>Cc1cc(OC(=O)N(CF)CF)cc(C(C)C)c1,,ClCCl,,CCN(CC)CC,,test
US20150038438A1,CI.C[Si](C)(C)C#Cc1cc(C#N)c(Cl)cc1N>>Cn1ccc2cc(C#N)c(Cl)cc21,,CN(C)C=O,,Cl,CC(C)(C)[O-].[K+],test
US20020052509A1,F[B-](F)(F)F.NCc1cnc2ccccc2c1.c1ccc(-c2cc(-c3ccccc3)[o+]c(-c3ccccc3)c2)cc1>>F[B-](F)(F)F.c1ccc(-c2cc(-c3ccccc3)[n+](Cc3cnc4ccccc4c3)c(-c3ccccc3)c2)cc1,,ClCCl,,,,test
US20060166894A1,CC(C)(C)OC(=O)C(CCC(=O)O)NC(=O)OCc1ccccc1>>CC(C)(C)OC(=O)C(CCCO)NC(=O)OCc1ccccc1,,C1CCOC1,,CC(C)COC(=O)Cl,CCN(CC)CC,test
US20100160387A1,COc1cc(Br)c(CC(=O)O)cc1OC.O=C(Cl)C(=O)Cl>>COc1cc(Br)c(CC(=O)Cl)cc1OC,CN(C)C=O,ClCCl,,,,test
US20090221555A1,COc1ccc([N+](=O)[O-])c(-n2cccn2)c1>>COc1ccc(N)c(-n2cccn2)c1,[Pd],CCO,,,,test
US20110223102A1,C=CC1=C(C)c2cc3[nH]c(c4c5nc(cc6[nH]c(cc1n2)c(C)c6CC)C(C)=C5C(=O)C4)[C@@H](CCC(=O)O)[C@@H]3C>>C=Cc1c(C)c2cc3nc(c4c5[nH]c(cc6nc(cc1[nH]2)C(C)=C6CC)c(C)c5C(=O)C4)[C@@H](CCC(=O)O)[C@@H]3C,,ClCCl,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US05677114,COC(=O)CC(=O)C(C)(C)C.COc1ccc([N+](=O)[O-])cc1N>>COc1ccc([N+](=O)[O-])cc1NC(=O)CC(=O)C(C)(C)C,,Cc1ccccc1,,CO,,test
US20120172351A1,CCN(c1ccccc1)c1cccc2c1OC[C@H]2N(C(=O)C(F)(F)F)c1ccc2c(c1)OC[C@H]2CC(=O)OC>>CCN(c1ccccc1)c1cccc2c1OC[C@H]2Nc1ccc2c(c1)OC[C@H]2CC(=O)O,,C1CCOC1,CO,[Na+].[OH-],,test
US20100286126A1,CC(=O)OCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(O)(c4ccc(Cl)cc4)c4ccc(Cl)cc4)nc(N4CC[C@@H](NC(=O)OC(C)(C)C)C4)nc32)[C@H](O)[C@@H]1O>>N[C@@H]1CCN(c2nc(NCC(O)(c3ccc(Cl)cc3)c3ccc(Cl)cc3)c3ncn([C@@H]4C[C@H](NC(=O)CO)[C@@H](O)[C@H]4O)c3n2)C1,,C1COCCO1,CO,Cl,,test
US20130266563A1,CC(C)(C)c1cc(O)c(C#N)[se]1.O=C(O)C(F)(F)F>>CC(C)(C)c1cc(O)c(C(N)=O)[se]1,,O=C(O)C(F)(F)F,,O=S(=O)(O)O,,test
US20060235033A1,COc1cc2nccc(Oc3ccc(N)cc3F)c2cc1OC.Cc1cnc(C(C)N)s1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)NC(C)c4ncc(C)s4)cc3F)c2cc1OC,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20040082611A1,CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)CC1CC(=O)O.CS(N)(=O)=O.O=C(O)C(F)(F)F>>CS(=O)(=O)NC(=O)CC1CN(S(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)CCN1.O=C(O)C(F)(F)F,,C1CCOC1,ClCCl,C1CCC2=NCCCN2CC1,O=C(n1ccnc1)n1ccnc1,test
US05886210,CCC(=O)O.Cc1ccccc1.Cl[Cu]>>CC(=O)c1ccc(Cl)cc1,Cl[Cu],,,CN(C)C=O,Cl,test
US20150232435A1,CC(C)(C)c1cc(N2CCN(CCCCN)CC2)cc(C(C)(C)C)c1.O=C(n1ccnc1)n1ccnc1.c1ccc(N2CCNCC2)cc1>>CC(C)(C)c1cc(N2CCN(CCCCNC(=O)N3CCN(c4ccccc4)CC3)CC2)cc(C(C)(C)C)c1,,CO,ClC(Cl)Cl,,,test
US20100168418A1,COc1ccc2ncc(=O)n(CCN3CCC(NCc4ccc5c(c4)SCCS5)CC3)c2c1.Cl>>COc1ccc2ncc(=O)n(CCN3CCC(NCc4ccc5c(c4)SCCS5)CC3)c2c1.Cl,,CCOC(C)=O,,,,test
US20150329538A1,CC(C)(C)Nc1nc2c(-c3cc4c([nH]3)CCNC4=O)cccc2nc1F.CN>>CNc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1NC(C)(C)C,,CS(C)=O,ClCCl,CCN(C(C)C)C(C)C,Cl,test
US20050267095A1,CC(C)(C)OC(=O)N1CCC(CCO)CC1.CI.Cl>>COCCC1CCNCC1.Cl,,C1CCOC1,CCO,[H-].[Na+],,test
US20090163488A1,Cc1cc(C(=O)O)n(CC(F)(F)F)n1.Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)ccc1F>>Cc1cc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)nn4c3)ccc2F)n(CC(F)(F)F)n1,CN(C)C=O,CC(=O)N(C)C,,C1CCOC1,O=C(Cl)C(=O)Cl,test
US20080096955A1,Fc1cc(Br)ccc1CN1CCCC1.O=C1CC(C(=O)O)C1>>O=C(O)C1CC(O)(c2ccc(CN3CCCC3)c(F)c2)C1,,C1CCOC1,,[Li]CCCC,,test
US06130217,Brc1nccs1.COc1cccc(O)c1>>COc1cccc(Oc2nccs2)c1,,CN(C)C=O,,,,test
US20130060041A1,CCC1=NNCC1.CCN=C=S>>CCNC(=S)N1CCC(CC)=N1,,CCO,,,,test
US20040048881A1,COc1cc2c(Nc3c(Cl)ccc4ccoc34)ncnc2cc1O.OCCN1CCCC1>>COc1cc2c(Nc3c(Cl)ccc4ccoc34)ncnc2cc1OCCN1CCCC1,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04695578,Cc1nccn1CC1CCc2c(c3ccccc3n2C)C1=O.O=P(O)(O)O>>Cc1nccn1CC1CCc2c(c3ccccc3n2C)C1=O.O=P(O)(O)O,,O,,,,test
US09433622B2,CO[C@H]1CCNC1.O=Cc1ccc([N+](=O)[O-])cn1>>CO[C@H]1CCN(Cc2ccc([N+](=O)[O-])cn2)C1,,ClCCl,O,CC(=O)O,O=C([O-])O.[Na+],test
US20100273786A1,CN(C)C(=O)c1nc(C(F)(F)F)n2c1CN(C(=O)C[C@@H](Cc1cc(F)c(F)cc1F)NC(=O)OC(C)(C)C)CC2.Cl>>CN(C)C(=O)c1nc(C(F)(F)F)n2c1CN(C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F)CC2.Cl,,CCOC(C)=O,,,,test
US20040192733A1,CN(C)C=O.O=C(O)C1(CS(=O)(=O)N2CCC(Oc3ccc(C(F)(F)F)cc3)CC2)CCOCC1>>O=C(NO)C1(CS(=O)(=O)N2CCC(Oc3ccc(C(F)(F)F)cc3)CC2)CCOCC1,,C1CCOC1,,O=C(Cl)C(=O)Cl,,test
US20120184526A1,COc1ccc(CO)cc1.Cn1cnc2cc(Cl)nc(Cl)c2c1=O>>COc1ccc(COc2nc(Cl)cc3ncn(C)c(=O)c23)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20070191364A1,CN(C)NC(=O)N(C1CCCCC1)C1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)N[C@H]2CC[C@@H](NC(=O)OC(C)(C)C)CC2)CC1>>CN(C)NC(=O)N(C1CCCCC1)C1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)N[C@@H]2CC[C@H](N)CC2)CC1,,C1COCCO1,,Cl,,test
US20100298336A1,CCc1cnccc1C(=O)OC>>CCc1cnccc1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100041667A1,CCOC(=O)C1(C(=O)OCC)C(c2ccccc2)CC(O)N1C(C)=O>>CCOC(=O)C1(C(=O)OCC)C(c2ccccc2)CCN1C(C)=O,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20020091265A1,COC(=O)c1cnccc1Cl.Cc1ccccc1B(O)O>>COC(=O)c1cnccc1-c1ccccc1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20150315188A1,CCOC(=O)c1ccc2c(c1)c1c(n2CC(O)c2ccncc2)CCN2CCCC12>>CC(O)c1ccncc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120077799A1,Cc1cc(C2=CC=CN3CCS(=O)(=O)N=C23)ccc1-c1ccccc1>>Cc1cc(C2CCCN3CCS(=O)(=O)N=C23)ccc1-c1ccccc1,O=[Pt]=O,C1CCOC1,CO,,,test
US20100137446A1,COc1ccc2cccc(C(CO)CNC(C)=O)c2c1.CS(=O)(=O)Cl>>COc1ccc2cccc(C(CNC(C)=O)COS(C)(=O)=O)c2c1,,ClCCl,,CCN(CC)CC,O,test
US20150291558A1,COc1c(C#N)ccnc1O[C@@H]1CC[C@@H](C)N(C(=O)OC(C)(C)C)C1.Cl>>C[C@@H]1CC[C@@H](Oc2cc(C#N)ccn2)CN1.Cl,,ClCCl,,,,test
US20150025068A1,COC(=O)c1ccc(N)cc1O.O=S(=O)(Cl)c1cnc(Cl)c(Br)c1>>COC(=O)c1ccc(NS(=O)(=O)c2cnc(Cl)c(Br)c2)cc1O,,Cc1ccccc1,,,,test
US20100120761A1,CC1(C)OB(c2ccc(N)cc2)OC1(C)C.COCC(=O)Cl>>COCC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US04289696,CCS.COC(=O)C1=CCC2CC(=O)N12>>CCSC1CC2CC(=O)N2C1C(=O)OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020193367A1,CC(C)(C)OC(=O)Nc1cc(F)c(C#N)cc1[N+](=O)[O-].CNCC(C)C>>CC(C)CN(C)c1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1C#N,,CS(C)=O,,,,test
US03960868,CCOC(=O)c1cnc2ccc(C3CCCCCC3)cc2c1Cl.NC(N)=S>>CCOC(=O)c1cnc2ccc(C3CCCCCC3)cc2c1SC(=N)N.Cl,,CCO,CO,,,test
US20050282819A1,O=C(NC1CCc2ccc(CCN3CCN(c4nsc5ccccc45)CC3)cc21)C(F)(F)F>>NC1CCc2ccc(CCN3CCN(c4nsc5ccccc45)CC3)cc21,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20060183758A1,Nc1ncccc1I.O=C1CCC(=O)N1Br>>Nc1ncc(Br)cc1I,,O,,ClCCl,,test
US20140038919A1,CS(=O)(=O)N(CCC/C(N)=N/O)c1cc2oc(-c3ccc(F)cc3)c(-c3ncc[nH]3)c2cc1C1CC1.S=C(n1ccnc1)n1ccnc1>>CS(=O)(=O)N(CCC/C(N)=N/OC(=S)n1ccnc1)c1cc2oc(-c3ccc(F)cc3)c(-c3ncc[nH]3)c2cc1C1CC1,,C1CCOC1,,CCOC(C)=O,,test
US20150152047A1,CCS(=O)(=O)c1ccc(Cl)cc1CN.COc1cc(C(=O)O)cc(Cl)c1CN1CCC[C@H](N(C)C(=O)OC(C)(C)C)C1>>CCS(=O)(=O)c1ccc(Cl)cc1CNC(=O)c1cc(Cl)c(CN2CCC[C@H](N(C)C(=O)OC(C)(C)C)C2)c(OC)c1,,ClCCl,,Cl,,test
US20160264548A1,C/C=C/C(=O)Cl.NC(=O)c1cc(N2CCC(N)CC2)cnc1Oc1ccc(Oc2ccccc2)cc1>>C/C=C/C(=O)NC1CCN(c2cnc(Oc3ccc(Oc4ccccc4)cc3)c(C(N)=O)c2)CC1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04898871,COc1ccc2ccc(N3C(=O)c4ccccc4C3O)nc2n1.O=C(CCl)N1CCOCC1>>COc1ccc2ccc(N3C(=O)c4ccccc4C3OCC(=O)N3CCOCC3)nc2n1,,CN(C)C=O,,[H-].[Na+],,test
US20150005289A1,CC(C)(C)OC(=O)NC[C@@H]1CCNC1.Cc1cn2nc(-c3cc(=O)n4cc(F)ccc4n3)cc2c(C)n1>>Cc1cn2nc(-c3cc(=O)n4cc(N5CC[C@@H](CNC(=O)OC(C)(C)C)C5)ccc4n3)cc2c(C)n1,,CC(=O)N(C)C,,,,test
US20160016966A1,CC(=O)N(C)c1cc(B2OC(C)(C)C(C)(C)O2)ccn1.C[C@@H]1CN(S(C)(=O)=O)CCN1Cc1cc2c(=O)n(C)cc(Br)c2o1>>CC(=O)N(C)c1cc(-c2cn(C)c(=O)c3cc(CN4CCN(S(C)(=O)=O)C[C@H]4C)oc23)ccn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US04279637,CCOC(=O)Cl.Nc1cc(Cl)c(Oc2cc(Cl)cc(Cl)c2)c(Cl)c1>>CCOC(=O)Nc1cc(Cl)c(Oc2cc(Cl)cc(Cl)c2)c(Cl)c1,,c1ccncc1,,,,test
US20060122168A1,CCOC(=O)CN(Cc1ccccc1)Cc1ccccc1.O=CCCOCc1ccccc1>>CCOC(=O)C(C(O)CCOCc1ccccc1)N(Cc1ccccc1)Cc1ccccc1,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20070249597A1,CCN=C=O.Cn1nc(C2CCN(C(=O)OCc3ccccc3)C2)c(C2=CCCCC2)c1N>>Cn1nc(C2CCN(C(=O)OCc3ccccc3)C2)c2c3c(c(=O)[nH]c21)CCCC3,,c1ccncc1,,,,test
US20150252038A1,COC(=O)c1cc(C2CC2)c(O[C@@H]2CCCNC2)cc1F.Fc1ccc(CBr)c(C(F)(F)F)c1>>COC(=O)c1cc(C2CC2)c(O[C@@H]2CCCN(Cc3ccc(F)cc3C(F)(F)F)C2)cc1F,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060069088A1,COC(=O)c1cc(C2=CCN(C(=O)OC(C)(C)C)CC2)ccc1F>>COC(=O)c1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1F,[Pd],CCO,,[H][H],,test
US04526897,Cc1ccc(C)c2c1CN(NC(=O)OC(C)(C)C)C2>>Cc1ccc(C)c2c1CN(N)C2,,Cl,,,,test
US20110070192A1,Cc1c[nH]c(=O)n(COCC[Si](C)(C)C)c1=O.O=S(=O)(O[C@H]1CO[C@@H]2COC(c3ccccc3)O[C@H]2[C@H]1F)C(F)(F)F>>Cc1cn([C@@H]2CO[C@@H]3COC(c4ccccc4)O[C@H]3[C@H]2F)c(=O)n(COCC[Si](C)(C)C)c1=O,,CN(C)C=O,,[H-].[Na+],,test
US20030069427A1,C=CC[Si](C)(C)C.COc1cccc2c1-c1ccc3c(c1C(O)O2)C(C)=CC(C)(C)N3>>C=CCOC1Oc2cccc(OC)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3,,ClCCl,,,,test
US20060142263A1,Cc1nc(N2C[C@H](NC(=O)OCc3ccccc3)CC2=O)ccc1N.O=C(Cl)COCCCl>>Cc1nc(N2C[C@H](NC(=O)OCc3ccccc3)CC2=O)ccc1NC(=O)COCCCl,,C1CCOC1,,CCN(CC)CC,O,test
US04165372,CCCCBr.COc1cc2c(c(Br)c1OC)CCNCC2c1ccccc1>>CCCCN1CCc2c(cc(OC)c(OC)c2Br)C(c2ccccc2)C1,,CO,,[K+].[OH-],,test
US20030073846A1,CI.O=S(=O)(Nc1cc(C[C@@H](CO)N(Cc2ccccc2)C[C@H](O)COc2ccccc2)ccc1OCc1ccccc1)c1ccccc1>>CN(c1cc(C[C@@H](CO)NC[C@H](O)COc2ccccc2)ccc1O)S(=O)(=O)c1ccccc1,,CCOC(C)=O,ClCCl,c1ccncc1,O=C([O-])O.[Na+],test
US04937350,Cc1c(Br)cc(Cl)c(NS(=O)(=O)c2n[nH]c(NC=O)n2)c1Cl>>Cc1ccc(Cl)c(NS(=O)(=O)c2n[nH]c(N)n2)c1Cl,,CCO,,[H][H],,test
US20100305096A1,CC(C)(C)OC(=O)N1CC(C(=O)N2CC[C@H](O)C2)C1>>O=C(C1CNC1)N1CC[C@H](O)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080255160A1,Cn1c(=O)c(F)c(Nc2ccc(I)cc2F)c2c(=O)[nH]cnc21.OCCBr>>Cn1c(=O)c(F)c(Nc2ccc(I)cc2F)c2c(=O)n(CCO)cnc21,,CN(C)C=O,,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US20080182854A1,BrC(Br)(Br)Br.CC(C)(C)OC(=O)/C=C/c1cccc(CO)n1>>CC(C)(C)OC(=O)/C=C/c1cccc(CBr)n1,,ClC(Cl)Cl,ClCCl,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20020193405A1,Brc1cccc(Br)n1.O[C@H]1CCOC1>>Brc1cccc(OC2CCOC2)n1,,C1CCOC1,,[H-].[Na+],,test
US20150152068A1,Cc1c(B2OC(C)(C)C(C)(C)O2)cc(F)cc1[N+](=O)[O-]>>Cc1c(N)cc(F)cc1B1OC(C)(C)C(C)(C)O1,[Pd],CCOC(C)=O,,,,test
US20050209241A1,COC(=O)c1cc(C(C)=O)ccc1OC(C)C>>CC(=O)c1ccc(OC(C)C)c(C(=O)O)c1,,C1CCOC1,,[Na+].[OH-],,test
US20130245305A1,Nc1ccc(C(=O)O)cc1.S=C(n1ccnc1)n1ccnc1>>O=C(O)c1ccc(N=C=S)cc1,,CCCCCCC,ClCCl,CCN(CC)CC,Cl,test
US20110294781A1,C1COCCN1.Clc1cc(Cl)n2nc(-c3ccco3)cc2n1>>Clc1cc(N2CCOCC2)n2nc(-c3ccco3)cc2n1,,C1COCCO1,,,,test
US20040116475A1,COc1ccc(-n2nc(NC(=O)OC(C)(C)C)cc2-c2ccc(OCCNC(N)=O)cc2)cc1>>COc1ccc(-n2nc(N)cc2-c2ccc(OCCNC(N)=O)cc2)cc1,,C1COCCO1,ClCCl,,,test
US20050245518A1,COC(=O)c1ccc(C=C2SC(=O)NC2=O)cc1>>COC(=O)c1ccc(CC2SC(=O)NC2=O)cc1,[Pd],CO,,,,test
US20110224188A1,CC(C)(C)OC(=O)NC1(c2ccc3cc[nH]c3n2)CC1>>CCC(N)c1ccc2cc[nH]c2n1,,C1COCCO1,,Cl,,test
US20050222148A1,OB(O)c1ccccc1F.OC[C@@H](O)[C@H](c1cccc(F)c1)n1cc(I)c2ccccc21>>OC[C@@H](O)[C@H](c1cccc(F)c1)n1cc(-c2ccccc2F)c2ccccc21,,CN(C)C=O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US06130237,CC(C)(C)OC(=O)Nc1cc2c(c3ccccc13)C(CCl)CN2C(=O)C(F)(F)F.COc1ccc(/C=C/C(=O)Cl)cc1>>COc1ccc(/C=C/C(=O)N2CC(CCl)c3c2cc(NC(=O)OC(C)(C)C)c2ccccc32)cc1,CN(C)c1ccncc1,CN1CCCC1=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060122263A1,C=C[Mg]Br.c1ccc(C(c2ccccc2)[C@@H]2CO2)cc1>>C=CC[C@H](O)C(c1ccccc1)c1ccccc1,[Cu]I,C1CCOC1,,,,test
US20030176418A1,Cc1c(Cl)cc2c(c1Cl)OCC(=O)N2.ClCCCI>>Cc1c(Cl)cc2c(c1Cl)OCC(=O)N2CCCCl,,CCCCCCC,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05600009,CC(=O)CCO.CC(=O)O>>CC(=O)CCOC(C)=O,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20150259478A1,C=CCCCCCCCC(=O)O.CO>>C=CCCCCCCCC(=O)OC,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090023763A1,CC1(C)OB(c2ccncc2)OC1(C)C.Nc1ccc(Br)c(-c2cccc(F)c2)n1>>Nc1ccc(-c2ccncc2)c(-c2cccc(F)c2)n1,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120130068A1,CI.CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)[C@@H]3[C@H]4CC[C@H](C4)[C@@H]3N(Cc3ccc(F)c(F)c3)C1=O)N2>>CN(c1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)[C@@H]3[C@H]4CC[C@H](C4)[C@@H]3N(Cc3ccc(F)c(F)c3)C1=O)N2)S(C)(=O)=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130217664A1,CCc1cc(C2CN(C(=O)OC(C)(C)C)C2)ncc1Nc1cc2c(cn1)ncn2C.CI>>CCc1cc(C2CN(C(=O)OC(C)(C)C)C2)ncc1N(C)c1cc2c(cn1)ncn2C,,C1CCOC1,,[H-].[Na+],,test
US20040133011A1,CCS(=O)(=O)CCCC12CCC(C(=O)OC)(CC1)CC2>>CCS(=O)(=O)CCCC12CCC(C(=O)O)(CC1)CC2,,CO,O,Cl,[K+].[OH-],test
US20160083365A1,CCOC(=O)/N=N/C(=O)OCC.Nc1ccc(Cl)c(O)c1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>Nc1ccc(Cl)c(OCc2ccccn2)c1,,C1CCOC1,,,,test
US20100016401A1,Cc1ccc(C(=O)N2C[C@H]3C[C@H]3[C@H]2CNC(=O)OC(C)(C)C)c(Br)c1.OB(O)c1cccc(F)c1>>Cc1ccc(C(=O)N2C[C@H]3C[C@H]3[C@H]2CNC(=O)OC(C)(C)C)c(-c2cccc(F)c2)c1,,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20030176449A1,Brc1cccc(-c2ccccc2-n2cncn2)c1.CCCC[Sn](CCCC)(CCCC)c1cnc2nc(C(F)(F)F)ccn12>>FC(F)(F)c1ccn2c(-c3cccc(-c4ccccc4-n4cncn4)c3)cnc2n1,,CO,ClCCl,,,test
US20100210623A1,Cn1cc(-c2cnc3c(ccn3S(=O)(=O)c3ccccc3)c2)cn1.O=C1CCC(=O)N1Br>>Cn1cc(-c2cnc3c(c2)c(Br)cn3S(=O)(=O)c2ccccc2)cn1,,C1CCOC1,,,,test
US20010020033A1,CN(C)C=O.Cc1ccc(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)OC(C)(C)C)C(=O)O)cc1>>CON(C)C(=O)[C@H](CCCNC(=N)NS(=O)(=O)c1ccc(C)cc1)NC(=O)OC(C)(C)C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US06518257B1,CC(C)C(O)(c1cccc(Br)c1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1.CCCC[Sn](CCCC)(CCCC)c1ccco1>>CC(C)C(O)(c1cccc(-c2ccco2)c1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20100004245A1,CC(C)(C)[Si](C)(C)Cl.OC1CCN(c2ccc(Br)cn2)CC1>>CC(C)(C)[Si](C)(C)OC1CCN(c2ccc(Br)cn2)CC1,CN(C)c1ccncc1,CN(C)C=O,,c1c[nH]cn1,,test
US20150148340A1,CC(=O)OC(C)=O.CC1(C)CNc2cc(-n3cc(C(=O)O)c(=O)n(Cc4cccc(C(F)(F)F)c4Cl)c3=O)ccc21>>CC(=O)N1CC(C)(C)c2ccc(-n3cc(C(=O)O)c(=O)n(Cc4cccc(C(F)(F)F)c4Cl)c3=O)cc21,,C1CCOC1,,CCN(CC)CC,Cl,test
US20100267688A1,COc1ncccc1C1=CCC2(CC1)OCCO2>>COc1ncccc1C1=CCC(=O)CC1,,CC#N,,Cl,,test
US04497806,O=C(O)c1ccc([N+](=O)[O-])o1.c1ccc([Sn](O[Sn](c2ccccc2)(c2ccccc2)c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>O=C([O-])c1ccc([N+](=O)[O-])o1.c1ccc([Sn+](c2ccccc2)c2ccccc2)cc1,,c1ccccc1,,,,test
US20090054427A1,C=CCOC(=O)CC(=O)C(CSC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)OC(C)(C)C.C=O>>C=CCOC(=O)C1CSCC(NC(=O)OC(C)(C)C)C1=O,,CC(=O)O,,C1CCNCC1,,test
US04020084,CN(C)c1ccc(C2N(c3ccccc3)CCN2c2ccccc2)c(O)c1.O>>CN(C)c1ccc(C=O)c(O)c1,,CCO,,Cl,,test
US20110237588A1,CC(C)I.CSc1nccc(-c2c[nH]nc2-c2ccc(Cl)s2)n1>>CSc1nccc(-c2cn(C(C)C)nc2-c2ccc(Cl)s2)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04638078,CCOC(=O)CC#N.ClCc1ccccc1Cl>>CCOC(=O)C(C#N)Cc1ccccc1Cl,,CCO,,[Na],,test
US20100216806A1,CC(C)(C)OC(=O)CP(=O)(O)O.CCOC(=O)c1cc2ccc(C=O)cc2s1>>CCOC(=O)c1cc2ccc(C=CC(=O)OC(C)(C)C)cc2s1,,C1CCOC1,,[Li]CCCC,,test
US05336778,CCCCc1nnc(SCC(=O)OC)n1Cc1ccc(N)cc1.O=C1OC(=O)c2ccccc21>>CCCCc1nnc(SCC(=O)OC)n1Cc1ccc(NC(=O)c2ccccc2C(=O)O)cc1,,C1CCOC1,,,,test
US20020165241A1,Cc1cnc(NCC2CCNCC2)nc1.O=C(O)[C@@H]1C[C@H]1c1ccccc1>>Cc1cnc(NCC2CCN(C(=O)[C@@H]3C[C@H]3c3ccccc3)CC2)nc1,,CCOC(C)=O,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
US20130109678A1,CC(=O)OC(C)=O.COC(=O)c1ccc(N)cc1OC>>COC(=O)c1ccc(NC(C)=O)cc1OC,,CCO,,,,test
US20070037807A1,CC(C)(C)C(=O)OCCl.Cc1ccc(-c2c(CNC(=O)OC(C)(C)C)c(CC(C)C)nc(C)c2C(=O)O)cc1>>Cc1ccc(-c2c(CNC(=O)OC(C)(C)C)c(CC(C)C)nc(C)c2C(=O)OCOC(=O)C(C)(C)C)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20100041891A1,CCOC(=O)c1cccc(-c2ncnc3cc(CO)sc23)c1.O=S(Cl)Cl>>CCOC(=O)c1cccc(-c2ncnc3cc(CCl)sc23)c1,,ClCCl,,,,test
US20020119983A1,O=CCCc1cc(-c2ccccc2)no1.c1ccc(CN2CCNCC2)cc1>>c1ccc(CN2CCN(CCCc3cc(-c4ccccc4)no3)CC2)cc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20160264567A1,CC(C)(C)OC(=O)NCc1cc(C(F)(F)F)nc(C2CC2)n1.Cl>>Cl.NCc1cc(C(F)(F)F)nc(C2CC2)n1,,C1COCCO1,,,,test
US20100035898A1,Cc1n[nH]c(C)c1Cl.Cc1ncc(Cl)cc1C(=O)N[C@@H]1CC[C@@H](COS(C)(=O)=O)CC1>>Cc1ncc(Cl)cc1C(=O)N[C@@H]1CC[C@@H](Cn2nc(C)c(Cl)c2C)CC1,,CC#N,O,[H-].[Na+],,test
US05071999,C=CCN(CC=O)C(=O)OCC.O=C(O)[C@@H]1CCCN1>>CCOC(=O)N1CC2CC3CCCN3C2C1,,Cc1ccccc1,,,,test
US20160194302A1,CCOC(=O)Cn1ccnc1CCC(=O)O.CN(C)C1CCNCC1>>CCOC(=O)Cn1ccnc1CCC(=O)N1CCC(N(C)C)CC1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04623662,CCCCc1ccc(CNCCCCCCO)cc1.O=C(Cl)Oc1ccccc1>>CCCCc1ccc(CN(CCCCCCO)C(=O)Oc2ccccc2)cc1,,Cc1ccccc1,,,,test
US20100041711A1,C1CCOC1.CC(=O)O.CC(C)CC=O.CO.[BH3-]C#N>>CC(C)CCNC1CCC(C)CC1,,O,,[Na+].[OH-],,test
US05455339,CC(=O)Nc1ccn([C@H]2CC[C@@H](CO)O2)c(=O)n1>>Nc1ccn([C@H]2CC[C@@H](CO)O2)c(=O)n1,,CO,,N,,test
US20090286811A1,COc1cccc(C=O)c1OC1CCCC1.Cc1nc2sccn2c(=O)c1-c1ccc(C(F)(F)F)cc1>>COc1cccc(/C=C/c2nc3sccn3c(=O)c2-c2ccc(C(F)(F)F)cc2)c1OC1CCCC1,,CCO,,C,C[O-].[Na+],test
US20110053936A1,CCOC(=O)c1cnc(C)c(Br)c1>>Cc1ncc(C(=O)O)cc1Br,,CCO,,[Na+].[OH-],,test
US20160272598A1,CC1(C)COC(=O)N1I.COc1ccc(CCC(=O)O)cc1>>COc1ccc(CCI)cc1,,ClCCl,,,,test
US05225431,CNC(=O)c1cccc(CCl)c1.O=C1NC(=O)C(Cc2ccc([N+](=O)[O-])cc2)N1>>CNC(=O)c1cccc(CN2C(=O)NC(Cc3ccc([N+](=O)[O-])cc3)C2=O)c1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20060094767A1,CC1(CCOS(C)(=O)=O)Cn2cc([N+](=O)[O-])nc2O1.O=c1[nH]nc(-c2ccncc2)o1>>CC1(CCn2nc(-c3ccncc3)oc2=O)Cn2cc([N+](=O)[O-])nc2O1,,CN(C)C=O,O,[H-].[Na+],,test
US20090036485A1,COc1cc2nccc(Oc3cnn(CC(=O)Nc4cc(C)cc(CN(C(=O)OC(C)(C)C)C5CC5)c4)c3)c2cc1C#N>>COc1cc2nccc(Oc3cnn(CC(=O)Nc4cc(C)cc(CNC5CC5)c4)c3)c2cc1C#N,,ClCCl,,O=C(O)C(F)(F)F,,test
US04774319,Cc1cc(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)OC(C)(C)C)C(=O)O)c(C)c1.N>>Cc1cc(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)OC(C)(C)C)C(N)=O)c(C)c1,,C1CCOC1,,CN1CCOCC1,,test
US20040259912A1,COC(=O)c1cc(N)ccc1OC(c1ccccc1)c1ccccc1.O=C=Nc1ccccc1>>COC(=O)c1cc(NC(=O)Nc2ccccc2)ccc1OC(c1ccccc1)c1ccccc1,,O,,C1CCOC1,,test
US04000164,CCC=CCC=CCC=CCCCCCCCCO.O=C(O)c1ccc(Br)o1>>CCC=CCC=CCC=CCCCCCCCCOc1ccc(C(=O)O)o1,,Cc1ccccc1,,CC(C)(C)O,CC(C)(C)[O-].[K+],test
US04891432,CCOC(=O)C(C)(C)CCCCOc1ccc(OCCCCCBr)cc1.Sc1nc2ncccc2[nH]1>>CCOC(=O)C(C)(C)CCCCOc1ccc(OCCCCCSc2nc3ncccc3[nH]2)cc1,,O,,CO,[Na+].[OH-],test
US20100278833A1,COC(=O)c1sc(-n2cnc3ccncc32)cc1O.COC(=O)c1sc(-n2cnc3cnccc32)cc1O.FC(F)(F)c1ccccc1CBr>>COC(=O)c1sc(-n2cnc3ccncc32)cc1OCc1ccccc1C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060194844A1,CCOC(=O)C1CCN(c2ncc(C(=O)Nc3nc(-c4cc(Cl)cs4)c(CN(C)CCOC)s3)cc2Cl)CC1.Cl>>COCCN(C)Cc1sc(NC(=O)c2cnc(N3CCC(C(=O)O)CC3)c(Cl)c2)nc1-c1cc(Cl)cs1.Cl,,O,,CCO,[Na+].[OH-],test
US20150252044A1,CS(=O)(=O)NN.O=C(O)c1ccc2cncc(-c3ccc(Cl)cc3)c2n1>>CS(=O)(=O)NNC(=O)c1ccc2cncc(-c3ccc(Cl)cc3)c2n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05716756,CC(O)(c1ccccc1)C(F)(F)F.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OC(C)(c2ccccc2)C(F)(F)F)cc1,,CCOCC,,[H-].[Na+],,test
US20070066624A1,Cc1nc(Cl)ccc1C=O.O=C(NC1CC1)c1ccc(O)cc1>>Cc1nc(Oc2ccc(C(=O)NC3CC3)cc2)ccc1C=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05912353,CCc1nnc(N)s1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCc1nnc(NC(=O)C(F)(F)F)s1,,Cc1ccccc1,,CCN(CC)CC,O,test
US20020132796A1,CC1(C)CCC(=O)c2ccc(O)cc21.O=S(=O)(N(c1ccc(Cl)cn1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC1(C)CCC(=O)c2ccc(OS(=O)(=O)C(F)(F)F)cc21,CN(C)c1ccncc1,ClCCl,,,,test
US20040048826A1,CC(C)C(=O)Cl.CCCCCO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(=O)[nH]c(N)nc21>>CCCCCO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(=O)[nH]c(NC(=O)C(C)C)nc21,,c1ccncc1,,C[Si](C)(C)Cl,,test
US20030207888A1,CI.C[C@@H](O)c1ccc2c(n1)N1[C@H](C2)CN(C(=O)OC(C)(C)C)C[C@H]1C>>CO[C@H](C)c1ccc2c(n1)N1[C@H](C2)CN(C(=O)OC(C)(C)C)C[C@H]1C,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20020052322A1,CCOC(=O)[C@@H](N)CO.C[C@H](NC(=O)Cc1cccc([N+](=O)[O-])c1)C(=O)O>>CCOC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)Cc1cccc([N+](=O)[O-])c1,,CO,ClC(Cl)Cl,Cl,,test
US04055410,COc1ccccc1NCN1C(=O)CSC1=O.O=C(Cl)CCl>>COc1ccccc1N(CN1C(=O)CSC1=O)C(=O)CCl,,ClC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US20090137561A1,COC(=O)c1cc(F)c(-c2cc(OC)ccc2F)c(C2CCCC2(C)C)c1>>COc1ccc(F)c(-c2c(F)cc(CO)cc2C2CCCC2(C)C)c1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20060074089A1,CCOC(=O)C(C(=O)c1cnc(SC)nc1OC)=C(SC)SC.CNC(=O)c1ccccc1N>>CCOC(=O)c1c(=O)c2cnc(SC)nc2n2c3ccccc3c(=O)n(C)c12,,Cc1ccccc1,,,,test
US20120115811A1,CC(C)(C)OC(=O)C(F)(F)c1cc(NC(=O)[C@@H](N)Cc2ccccc2)cc(-c2ccncc2)c1.O=Cc1cscn1>>O=C(Nc1cc(-c2ccncc2)cc(C(F)(F)C(=O)O)c1)[C@H](Cc1ccccc1)NCc1cscn1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130123500A1,Cn1ncc(C#C[Si](C)(C)C)c1-c1ccc(C(F)(F)F)cc1>>C#Cc1cnn(C)c1-c1ccc(C(F)(F)F)cc1,,CO,,C1CCOC1,O=C([O-])[O-].[K+].[K+],test
US05455258,COC(=O)C(C)N(Cc1ccccc1)S(=O)(=O)c1ccc(OC)cc1.NO>>COc1ccc(S(=O)(=O)N(Cc2ccccc2)C(C)C(=O)NO)cc1,,CO,,Cl,C[O-].[Na+],test
US06008230,CC(C)(C)OC(=O)n1[nH]c2c(cnc3c([N+](=O)[O-])cccc32)c1=O.CI>>Cn1c2c(cnc3c([N+](=O)[O-])cccc32)c(=O)n1C(=O)OC(C)(C)C,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04963553,CCC(=CN(C)C)C(=O)c1cccc(C(F)(F)F)c1.N#Cc1c[nH]nc1N>>CCc1cnc2c(C#N)cnn2c1-c1cccc(C(F)(F)F)c1,,CC(=O)O,,,,test
US20060217380A1,CC(C)N1CCNCC1.O=[N+]([O-])c1ccc(F)cc1>>CC(C)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20110144136A1,BrC(Br)(Br)Br.O=C(OCc1ccccc1)N1CCCCC1CCCO>>O=C(OCc1ccccc1)N1CCCCC1CCCBr,,ClCCl,ClCCl,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100197591A1,COC(=O)C1(c2ccc(N3CCC(O)=C(C#N)C3=O)cc2)CCC1.ClCCl>>COC(=O)C1(c2ccc(N3CCC(OC)=C(C#N)C3=O)cc2)CCC1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20150344466A1,C#CCCCO.CCOC(=O)C[N+](=O)[O-]>>CCOC(=O)c1cc(CCCO)on1,,CCO,,C1CN2CCN1CC2,,test
US05843973,CC(C)(C)OC(=O)NCC[C@@H]1CC[C@@H](CO[Si](C)(C)C(C)(C)C)CC1>>CC(C)(C)OC(=O)NCC[C@@H]1CC[C@@H](CO)CC1,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05028606,CC(=O)Nc1ccc(C(O)C(C)C)cc1[N+](=O)[O-].CS(=O)(=O)Cl>>CC(=O)Nc1ccc(C(Cl)C(C)C)cc1[N+](=O)[O-],,CCN(CC)CC,O,ClCCl,O=C([O-])[O-].[Na+].[Na+],test
US06403575B1,CCC(C)(C)N1CC[C@H]1COc1ccc(F)nc1.Cc1ccc(S(=O)(=O)O)cc1>>CCC(C)(C)N1CC[C@H]1COc1ccc(F)nc1.Cc1ccc(S(=O)(=O)O)cc1,,CCO,,,,test
US20140336377A1,CC(N[S@](=O)C(C)(C)C)c1ccc(OCC(F)(F)F)nc1.Cl>>CC(N)c1ccc(OCC(F)(F)F)nc1.Cl,,CO,,,,test
US04039577,C=C(C)c1ccccc1.CC(C)(Cl)c1ccccc1.NC(=O)Nc1ccccc1>>CC(C)(NC(=O)NC(C)(C)c1ccccc1)c1ccccc1,,CC#N,,,,test
US20160237095A1,COCc1ccc2c(c1)CN(S(=O)(=O)c1ccc(C)cc1)C2>>COCc1ccc2c(c1)CNC2,,CO,,CCN(CC)CC,,test
US20110237607A1,Clc1nc(NC2Cc3ccccc3C2)c2nc[nH]c2n1.NN>>NNc1nc(NC2Cc3ccccc3C2)c2nc[nH]c2n1,,C1CCOC1,,O,O,test
US20130190293A1,CC1(C)OB(c2ccc(F)nc2)OC1(C)C.Cc1ccc2c(c1)c1c(n2-c2cccc(Br)c2)CCN(C)C1>>Cc1ccc2c(c1)c1c(n2-c2cccc(-c3ccc(F)nc3)c2)CCN(C)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])[O-].[K+].[K+],test
US06207678B1,C=CC[C@H](CO)c1ccc(Cl)c(Cl)c1.CS(=O)(=O)Cl>>C=CC[C@H](COS(C)(=O)=O)c1ccc(Cl)c(Cl)c1,,ClCCl,,CCN(CC)CC,,test
US20090270412A1,C=O.CNCCc1cn(CCc2ccc(F)cc2)c2ccc(Cl)cc12>>CN1CCc2c(n(CCc3ccc(F)cc3)c3ccc(Cl)cc23)C1,,CC#N,,O=C(O)C(F)(F)F,,test
US20120083489A1,CC(=O)Cl.O=c1cc(OCc2ccc(Cl)cn2)ccn1-c1ccc(NCCN2CCCC2)nc1>>CC(=O)C(CN1CCCC1)Nc1ccc(-n2ccc(OCc3ccc(Cl)cn3)cc2=O)cn1,,ClCCl,,CCN(CC)CC,,test
US20140315911A1,COC(=O)[C@@H](C)N(c1nc(Cl)ncc1[N+](=O)[O-])C1CCC(F)(F)CC1>>C[C@@H]1C(=O)Nc2cnc(Cl)nc2N1C1CCC(F)(F)CC1,[Fe],CCO,,Cl,,test
US20110237573A1,Cc1cc(CC(=O)O)cnc1Cl.Nc1ccc(-c2cccnn2)cn1>>Cc1cc(CC(=O)Nc2ccc(-c3cccnn3)cn2)cnc1Cl,CN(C)c1ccncc1,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20100158818A1,CC(C)(CN1CCCCC1)[N+](=O)[O-].CI>>CC(C)(C[N+]1(C)CCCCC1)[N+](=O)[O-].[I-],,CCO,,,,test
US20040259808A1,CC(=O)SC[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)OC(C)(C)C>>CC(=O)SC[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20040023938A1,F[B-](F)(F)F.N#CSc1ccc([N+]#N)c(C#N)c1>>N#CSc1ccc(F)c(C#N)c1,,O,,,,test
US05981533,COc1ccc(-c2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)cc1>>Oc1ccc(-c2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)cc1,,c1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20070197612A1,CC(C)OC(=O)[C@@H]1CCC[C@H](C(=O)O)C1>>CC(C)OC(=O)[C@@H]1CCC[C@H](CO)C1,,C1CCOC1,,CCN(CC)CC,CCOC(=O)Cl,test
US04284644,CSc1ccc2c(c1)C(=O)C1(CC1)O2.O=C(OO)c1cccc(Cl)c1>>CS(=O)(=O)c1ccc2c(c1)C(=O)C1(CC1)O2,,ClCCl,,O,,test
US20020019527A1,N#Cc1ccc([N+](=O)[O-])cc1Cl.OB(O)c1cccc2ccccc12>>N#Cc1ccc([N+](=O)[O-])cc1-c1cccc2ccccc12,,C1COCCO1,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20140357642A1,Cc1ccc(C(=O)C(=O)c2ccc(C)cc2)cc1.Nc1cc(Cl)cnc1N>>Cc1ccc(-c2nc3cc(Cl)cnc3nc2-c2ccc(C)cc2)cc1,,CCO,,,,test
US20140315917A1,NC1CC1.O=C=NCCCl>>O=C(NCCCl)NC1CC1,,C1CCOC1,,,,test
US20140213586A1,COc1cccc(N)c1.Cn1cnc(S(=O)(=O)n2cc(C(=O)C(Cl)c3ccccc3)c3ccccc32)c1>>COc1cccc(NC(C(=O)c2cn(S(=O)(=O)c3cn(C)cn3)c3ccccc23)c2ccccc2)c1,,CC#N,,,,test
US20140303153A1,COCCBr.O=C1c2c(c[nH]c(=O)c2N2CCOCC2)CN1CCc1ccc2ccccc2n1>>COCCn1cc2c(c(N3CCOCC3)c1=O)C(=O)N(CCc1ccc3ccccc3n1)C2,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120101136A1,CCc1cccc(O)c1.ClCc1ccccc1>>CCc1cccc(OCc2ccccc2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070117836A1,CN(C)CCN1C(=O)c2cccc3cc(N)cc(c23)C1=O.O=C(Cl)CCCCl>>CN(C)CCN1C(=O)c2cccc3cc(NC(=O)CCCCl)cc(c23)C1=O,,CC#N,,,,test
US05237063,CO.Nc1nc(F)c(OC(F)F)c(Cl)n1>>COc1nc(N)nc(Cl)c1OC(F)F,,CO,,C[O-].[Na+],,test
US20070078121A1,CCOC(=O)C1Cc2cc(-n3nc(C(C)(C)C)cc3NC(=O)Nc3cccc(Oc4cccnc4)c3)ccc2CN1C(=O)OC(C)(C)C>>CC(C)(C)c1cc(NC(=O)Nc2cccc(Oc3cccnc3)c2)n(-c2ccc3c(c2)CC(C(=O)O)NC3)n1,,CO,Cl,,,test
US20110217311A1,O=[N+]([O-])c1ccc(F)cc1O[C@@H]1CC[C@H](O)CC1>>Nc1ccc(F)cc1O[C@@H]1CC[C@H](O)CC1,[Pd],CO,,[H][H],,test
US05250522,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(-c2ccccc2)cc1)C(=O)OCc1ccccc1.Cl>>Cl.N[C@@H](Cc1ccc(-c2ccccc2)cc1)C(=O)OCc1ccccc1,,CCOC(C)=O,,CCOCC,,test
US20150336894A1,CC(C)(C)c1ccc(C#Cc2ccncc2N)cc1.CSSC>>CSc1cnccc1C#Cc1ccc(C(C)(C)C)cc1,,ClC(Cl)Cl,,CC(C)(C)ON=O,,test
US20040224974A1,BrCC1CC1.CCc1nn2c(Br)cccc2c1NC(=O)OC(C)(C)C>>CCc1nn2c(Br)cccc2c1N(CC1CC1)C(=O)OC(C)(C)C,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20090093483A1,CC(C)(C)OC(=O)CNC(=O)C1=C(O)C(C)(C)c2cc(NCCN3CCOCC3)ccc2C1=O>>CC1(C)C(O)=C(C(=O)NCC(=O)O)C(=O)c2ccc(NCCN3CCOCC3)cc21,,O=C(O)C(F)(F)F,,,,test
US07973012B2,CC(=O)OC[C@H]1O[C@@H](c2cc(Cc3ccc(CCNC(=O)OC(C)(C)C)cc3)c(C)cc2OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>CC(=O)OC[C@H]1O[C@@H](c2cc(Cc3ccc(CCN)cc3)c(C)cc2OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20110076291A1,CC(C)n1ncnc1-c1nc2c(s1)CCOc1cc(C3CCNCC3)ccc1-2.CS(=O)(=O)Cl>>CC(C)n1ncnc1-c1nc2c(s1)CCOc1cc(C3CCN(S(C)(=O)=O)CC3)ccc1-2,,ClCCl,,CCN(CC)CC,O,test
US05424446,CC(=O)c1ccc(Cl)c(Cl)c1Cl>>CC(O)c1ccc(Cl)c(Cl)c1Cl,,CO,,[BH4-].[Na+],,test
US04939140,O=Cc1cc2cccnc2s1>>OCc1cc2cccnc2s1,,CCO,,[BH4-].[Na+],,test
US20040092582A1,C=C(C)Cc1cccc(OCC)c1O>>CCOc1cccc2c1OC(C)(C)C2,,Cc1ccccc1,,[Na+].[OH-],,test
US05554620,CCCCCCCCO.O=C(Br)CBr>>CCCCCCCCOC(=O)CBr,,ClCCl,,c1ccncc1,,test
US20110183938A1,CC(C)(C)OC(=O)N1CCC(Oc2c(C#N)ncc3c2c2cc(Br)cnc2n3S(=O)(=O)c2ccccc2)CC1>>N#Cc1ncc2c(c1OC1CCNCC1)c1cc(Br)cnc1n2S(=O)(=O)c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080045521A1,CCN(CC)CC.CN(C)C=O.COC(=O)[C@H](Cc1ccc(OS(=O)(=O)C(F)(F)F)cc1)NC(=O)c1c(Cl)cccc1Cl>>COC(=O)[C@H](Cc1ccc(C#CCO)cc1)NC(=O)c1c(Cl)cccc1Cl,[Cu]I,,,,,test
US20110076292A1,CS(=O)(=O)Cl.C[C@@H](O)C(N)=O>>C[C@@H](OS(C)(=O)=O)C(N)=O,,C1CCOC1,O,CCN(CC)CC,,test
US20100324043A1,CN(C)C(=O)Cl.N[C@H]1Cc2cc(Oc3ccccc3)ccc2N(O)C1=O>>CN(C)C(=O)ON1C(=O)[C@@H](N)Cc2cc(Oc3ccccc3)ccc21,,c1ccncc1,,Cl,,test
US20080096877A1,O=C(Cl)CCl.OCC1CN(Cc2ccccc2)CCN1>>O=C1COCC2CN(Cc3ccccc3)CCN12,,C1CCOC1,,O,O=C([O-])[O-].[K+].[K+],test
US06124280,O=C(NCC(c1ccc(O)c(CN2CCCCCC2)c1)c1ccc(O)c(CN2CCCCCC2)c1)c1ccccc1.O=C(O)C(=O)O>>O=C(NCC(c1ccc(O)c(CN2CCCCCC2)c1)c1ccc(O)c(CN2CCCCCC2)c1)c1ccccc1.O=C(O)C(=O)O,,CCO,,CCOC(C)=O,,test
US20120302755A1,CCN(CC)S(F)(F)F.O=[N+]([O-])c1ccncc1-c1ccc(CCCO)cc1>>O=[N+]([O-])c1ccncc1-c1ccc(CCCF)cc1,,ClCCl,,,,test
US20100222317A1,BrCC1CC1.C=C1CC(C#N)C1>>C=C1CC(C#N)(CC2CC2)C1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20090192144A1,COc1ccc(C(C)(N)C(=O)O)cc1>>COc1ccc(C(C)(N)CO)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090181965A1,BrBr.Cc1ccc(C)c(C2CCCCC2=O)c1>>Cc1ccc(C)c(C2CCCC(Br)C2=O)c1,,ClC(Cl)Cl,,,,test
US06180642B2,CC(C)(C)C(=O)Nc1cnc(C(C)(C)C(=O)N2CC3CCC2CC3)cc1I>>CC(C)(C(=O)N1CC2CCC1CC2)c1cc(I)c(N)cn1,,O=S(=O)(O)O,,[Na+].[OH-],,test
US20050032786A1,CC(=O)c1cccnc1C#N.COC(=O)c1ccccc1S>>CC(=O)c1ccc(-c2nc(=O)c3ccccc3s2)nc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20100173906A1,CCOCc1nc2c(N)nc3cccnc3c2n1CC(C)(C)O.O=S(Cl)Cl>>CCOCc1nc2c(N)nc3c4c2n1CC(C)(C)N4CCC3.Cl,,CCO,ClCCl,,,test
US20060074075A1,CC(C)(C)C1Cc2ccc([N+](=O)[O-])cc2N1>>CC(C)(C)c1cc2ccc([N+](=O)[O-])cc2[nH]1,,C1COCCO1,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US20030087915A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNCC/C=C/c1cccnc1>>CN(CC/C=C/c1cccnc1)C(=O)OC(C)(C)C,,C1CCOC1,,,,test
US20090105214A1,CN1CCOc2cc(F)c(F)cc2C1=O.COC[C@H](C)Oc1cc(O)cc(C(=O)Nc2ccn(C)n2)c1>>COC[C@H](C)Oc1cc(Oc2cc3c(cc2F)C(=O)N(C)CCO3)cc(C(=O)Nc2ccn(C)n2)c1,,CC(=O)N(C)C,,O,O=C([O-])[O-].[K+].[K+],test
US20160244437A1,Cc1ccc(S(=O)(=O)N2CCCC2)cc1-c1cccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3noc(=O)[nH]3)cc2)c1.Cl>>Cc1ccc(S(=O)(=O)N2CCCC2)cc1-c1cccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc(-c3noc(=O)[nH]3)cc2)c1.Cl,,C1COCCO1,,CC#N,,test
US20150376208A1,CCOC(=O)CC#N.O=[N+]([O-])c1ccc2ncccc2c1>>N#Cc1c(N)ccc2ncccc12,,CN(C)C=O,,[K+].[OH-],,test
US03974200,CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O>>CCCCC[C@H](O)/C=C/C1=C(C/C=C\CCCC(=O)O)C(=O)CC1,,CCO,,Cl,[K+].[OH-],test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(Cl)nc1-c1ccc(C)cc1.OB(O)c1ccccc1O>>CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2O)nc1-c1ccc(C)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,CCN(C(C)C)C(C)C,,test
US05057524,O=C(CCCl)Nc1ccccc1.OC(c1ccc(F)cc1)(c1ccc(F)cc1)C1CCNCC1>>O=C(CCN1CCC(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)CC1)Nc1ccccc1,,CN(C)C=O,O,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US07235572B2,Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1cccc2c1ccn2CC(=O)OC(C)(C)C>>Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1cccc2c1ccn2CC(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050124692A1,[N-]=[N+]=NCC1Cc2cc(Cl)c3c(c2O1)CCC3>>NCC1Cc2cc(Cl)c3c(c2O1)CCC3,[Pt],,,,,test
US20150119385A1,COC(OC)c1nc2c(cc1CN1CCSCC1=O)CCCN2.COCCNc1cc(N)ncc1C#N.O=C(n1cncn1)n1cncn1>>COCCNc1cc(NC(=O)N2CCCc3cc(CN4CCSCC4=O)c(C(OC)OC)nc32)ncc1C#N,,CN(C)C=O,,,,test
US20080139588A1,CC(N)C(C)(C)O.CS(=O)(=O)c1ncc2cc(C(=O)Nc3ccccc3Cl)n(-c3ccc(F)cc3)c2n1>>CC(Nc1ncc2cc(C(=O)Nc3ccccc3Cl)n(-c3ccc(F)cc3)c2n1)C(C)(C)O,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,Cl,test
US20020032208A1,COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1O.ClCCl.OCCc1ccncc1>>COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCc1ccncc1.Cl,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US07964618B2,CCCS.O=C(NC1CCCCC1)c1cc(F)c(Cl)nc1Cl>>CCCSc1nc(Cl)c(F)cc1C(=O)NC1CCCCC1,,C1CCOC1,CN(C)C=O,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20130053563A1,CC(=O)O.COCC(C)(C)C(=O)OCOc1nc(C(Nc2ccc(C(N)=NC(=O)c3ccccc3)cc2)c2cc(OC)cc(OCCOC(C)=O)c2F)nn1-c1ncccn1>>CC(=O)O.COCC(C)(C)C(=O)OCOc1nc(C(Nc2ccc(C(=N)N)cc2)c2cc(OC)cc(OCCOC(C)=O)c2F)nn1-c1ncccn1,,CC(=O)O,,CO,,test
US20030166638A1,CC(=O)N1CCN(c2cccc(N)c2)CC1.COC(=O)c1ccc(Cl)c([N+](=O)[O-])c1>>COC(=O)c1ccc(Nc2cccc(N3CCN(C(C)=O)CC3)c2)c([N+](=O)[O-])c1,,CN1CCCC1=O,,CCN(CC)CC,,test
US05025031,CNS(=O)(=O)Cl.OCCOc1ccccc1>>CNS(=O)(=O)OCCOc1ccccc1,,CC#N,,CCN(CC)CC,,test
US20090291988A1,NC(=O)C1(c2ccc(-c3ccc(C(=O)C(F)(F)F)cc3)cc2)CC1.[Li]C>>CC(O)(c1ccc(-c2ccc(C3(C(N)=O)CC3)cc2)cc1)C(F)(F)F,,C1CCOC1,,[Cl-].[NH4+],,test
US04992454,CC(C(=O)c1ccc(Cl)cc1)n1cncn1.CI>>CC(C)(C(=O)c1ccc(Cl)cc1)n1cncn1,,C1CCOC1,O,[H-].[Na+],,test
US03984427,C=C[Mg]Cl.CC1OC(C)(CCCC2CCCC(=O)O2)OC1C.CCOCC.CO>>C=CC(=O)CCCC(O)CCC(CC)C1(C)OC(C)C(C)O1,,CCOCC,,C1CCOC1,[Cl-].[NH4+],test
US04512795,CC(=O)OC(C)=O.OC1C2C=CC1C1N=NC21>>CC(=O)OC1C2C=CC1C1N=NC21,,CCOCC,,CCN(CC)CC,,test
US20070049595A1,CSc1ccccc1.O=C(O)Cc1ccc(Cl)cc1>>CSc1ccc(C(=O)Cc2ccc(Cl)cc2)cc1,,O,,,,test
US20090098047A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)N[C@@H]2CCCC[C@H]2N)cc1>>Cc1ccc(S(=O)(=O)N(C(=O)OC(C)(C)C)[C@@H]2CCCC[C@H]2N)cc1,,C1CCOC1,,[Na+].[OH-],,test
US20150232464A1,CCn1nnc(C(C)(CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)NC(=O)c2c(C)nc3c(OCc4c(F)cccc4F)cccn23)n1>>CCn1nnc(C(C)(CO)NC(=O)c2c(C)nc3c(OCc4c(F)cccc4F)cccn23)n1,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20050182053A1,CC(C)c1cc(=O)[nH]c(SCC(N)=O)c1C#N.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CCc1cc(OS(=O)(=O)C(F)(F)F)nc(SCC(N)=O)c1C#N,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05153226,CC(C)c1cccc(C(C)C)c1NC(=O)[C@@H](N)Cc1ccccc1.O=Cc1ccccc1>>CC(C)c1cccc(C(C)C)c1NC(=O)[C@H](Cc1ccccc1)NCc1ccccc1,[Ni],Cc1ccccc1,,O,,test
US20040082625A1,COc1ccc(B(O)O)cc1.COc1ccc(C=O)cc1Br>>COc1ccc(-c2cc(C=O)ccc2OC)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,COCCOC,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US20020045777A1,CN(C(=O)OC(C)(C)C)[C@@H]1CC[C@@H](C=C(Br)Br)CC1>>CN[C@@H]1CC[C@@H](C=C(Br)Br)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140199263A1,NC(=S)c1cncc(Br)c1.O=C1CCOCC1Br>>Brc1cncc(-c2nc3c(s2)COCC3)c1,,CCO,,,,test
US20090291917A1,CC#N.CCN(CC)CC.COCCNc1nc(Cl)ccc1C(N)=O.NC(=O)c1ccc(Cl)nc1Cl>>NC(=O)c1ccc(Cl)nc1NCCOCc1ccccc1,,CC#N,,,,test
US20090197864A1,Cc1ccc(N)cc1.O=C(O)c1cccn(-c2ccc(F)cc2)c1=O>>Cc1ccc(NC(=O)c2cccn(-c3ccc(F)cc3)c2=O)cc1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20150011461A1,Cn1cc(Br)cc(N)c1=O.O=C(O)C1CCC1>>Cn1cc(Br)cc(NC(=O)C2CCC2)c1=O,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070043048A1,CC(C)(C)OC(=O)N1CCC(N)CC12CCC2.Clc1ccnc(Cl)n1.OB(O)c1cc2ccccc2s1>>c1ccc2sc(-c3ccnc(NC4CCNC5(CCC5)C4)n3)cc2c1,,C1COCCO1,,Cl,,test
US20090076001A1,CCOC(=O)c1noc2c1CN(C(C)=O)CC2.Cl>>CCOC(=O)c1noc2c1CNCC2.Cl,,CCO,O,,,test
US20110160433A1,CCCCCCCCCCCCCCCCCCCCCCOc1cc(Cc2cc(OC)ccc2C=O)cc(OCCCCCCCCCCCCCCCCCCCCCC)c1>>CCCCCCCCCCCCCCCCCCCCCCOc1cc(Cc2cc(OC)ccc2CO)cc(OCCCCCCCCCCCCCCCCCCCCCC)c1,,C1CCOC1,CCO,Cl,[BH4-].[Na+],test
US20130190307A1,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.NNc1cnc2ccc(Br)cc2n1>>CC(C)(C)OC(=O)N1CCC(C(=O)NNc2cnc3ccc(Br)cc3n2)CC1,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20090130165A1,O=C(Br)CBr.O=c1[nH]c2cc(Cl)ccc2s1>>O=C(CBr)c1cc2sc(=O)[nH]c2cc1Cl,,CN(C)C=O,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20040077726A1,ClCCl.O=C(O)C=Cc1cccc(S(=O)(=O)NCc2cccnc2)c1>>O=C(Cl)C=Cc1cccc(S(=O)(=O)NCc2cccnc2)c1,CN(C)C=O,,,,,test
US20070208040A1,CCn1c(=O)[nH]c2sc(-c3ccco3)c(C)c2c1=O.CI>>CCn1c(=O)c2c(C)c(-c3ccco3)sc2n(C)c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140275027A1,Nc1ccc(Cl)c(Br)c1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(Nc1ccc(Cl)c(Br)c1)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20080242666A1,CCC(CC)[C@@H]1C(=O)N[C@H](C2Cc3ccccc3C2)C(=O)N1Cc1ccccc1S(=O)(=O)C1CCN(C(=O)OC(C)(C)C)CC1.Cl>>CCC(CC)[C@@H]1C(=O)N[C@H](C2Cc3ccccc3C2)C(=O)N1Cc1ccccc1S(=O)(=O)C1CCNCC1.Cl,,C1COCCO1,ClCCl,,,test
US20070219261A1,CCOC(=O)C(Cl)C(C)=O.CNC(=S)NN>>CCOC(=O)c1c(C)n[nH]c1NC,,C1CCOC1,,,,test
US04935437,CC(=O)C(C)(C)c1cc(Cn2cncn2)cc(C(C)(C)C#N)c1>>CC(O)C(C)(C)c1cc(Cn2cncn2)cc(C(C)(C)C#N)c1,,CCO,O,[BH4-].[Na+],,test
US04952574,NC(=O)CCl.O=C(NCc1ccccn1)c1cc(OCC(F)(F)F)ccc1O>>NC(=O)COc1ccc(OCC(F)(F)F)cc1C(=O)NCc1ccccn1,,CN(C)C=O,O,[H-].[Na+],,test
US05349065,CC(=O)c1c(O)ccc2ccccc12>>OC1CCc2ccccc2O1,,Cc1ccccc1,,C1COCCN1,,test
US20080194549A1,COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2CN(C)C(=O)C2CC2)C(C)C)ccc1OC>>COCCCOc1cc(C(=O)N(C[C@@H]2CNC[C@H]2CN(C)C(=O)C2CC2)C(C)C)ccc1OC,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20050148604A1,COc1cc(N2CC[C@@H](O[Si](C)(C)C(C)(C)C)C2)ccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1>>COc1cc(N2CC[C@@H](O)C2)ccc1-c1nc2c(C)nn(C3CCCCC3)c2c(=O)[nH]1,,O,,C1CCOC1,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US05446152,CCN(CC)CCN1CN(Cc2ccccc2)c2ccc(Cl)cc2C1=O.O=C(O)C(=O)O>>CCN(CC)CCN1CN(Cc2ccccc2)c2ccc(Cl)cc2C1=O.O=C(O)C(=O)O,,CCO,CCOCC,O,O,test
US20090286812A1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.COc1ccc(O)c(OC)n1>>COc1ccc(Oc2ncnc3c2cnn3C2CCN(C(=O)OC(C)(C)C)CC2)c(OC)n1,,CN(C)C=O,O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20110257011A1,Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C=O.NO>>Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C=NO,,CO,,Cl,Cl,test
US20060270653A1,CC(=O)N1Cc2ccccc2C2(CCN(C3CCC(=O)CC3)CC2)C1.CCON>>CCON=C1CCC(N2CCC3(CC2)CN(C(C)=O)Cc2ccccc23)CC1,,c1ccncc1,,Cl,,test
US20140187542A1,C=C(CC(=O)O)C(=O)O.Nc1ccc2c(c1)NC(=O)CO2>>O=C1COc2ccc(N3CC(C(=O)O)CC3=O)cc2N1,,O,,,,test
US04258187,CC(C)N=C=O.Nc1ccc(Cl)cc1C(=O)c1ccccc1>>CC(C)NC(=O)Nc1ccc(Cl)cc1C(=O)c1ccccc1,,CCCCCC,,,,test
US20120157430A1,COc1c(C(C)O)cc(Cl)c(F)c1C1CN(C(=O)OC(C)(C)C)C1.Clc1nc(Cl)nc(Cl)n1>>COc1c(C(C)Cl)cc(Cl)c(F)c1C1CN(C(=O)OC(C)(C)C)C1,,ClCCl,ClCCl,CN(C)C=O,O,test
US20160130253A1,Brc1cc(-c2ccncc2)c(-c2ccc3ccccc3c2)nn1.C1CCNC1>>c1ccc2cc(-c3nnc(N4CCCC4)cc3-c3ccncc3)ccc2c1,,CCOC(C)=O,,CCO,,test
US20160206616A1,CCOC(=O)C=CCC[C@@H]1CC(F)(F)CN1C(=O)OC(C)(C)C>>CCOC(=O)CCCC[C@@H]1CC(F)(F)CN1C(=O)OC(C)(C)C,[Pd],CCO,,,,test
US04117128,CCCCc1cc2ccccc2o1.COc1ccc(S(=O)(=O)Cl)cc1>>CCCCc1oc2ccccc2c1S(=O)(=O)c1ccc(OC)cc1,,O,,ClCCl,,test
US20110118257A1,Cl.O=c1c(-c2ccc(F)cc2)c(CN2CCOCC2)oc2ccc(Br)cc12>>Cl.O=c1c(-c2ccc(F)cc2)c(CN2CCOCC2)oc2ccc(Br)cc12,,C1CCOC1,CCOCC,,,test
US06136852,CCOC(=O)CCCCOc1ccc2c(c1)C[C@@H](NCC(O)c1ccc3c(c1)COC(C)(C)O3)CC2>>CCOC(=O)CCCCOc1ccc2c(c1)C[C@@H](NCC(O)c1ccc(O)c(CO)c1)CC2,,C1CCOC1,,Cl,,test
US20030191308A1,CC(C)(C)C(=O)OCCl.COc1cc2c(=O)[nH]cnc2cc1OCc1ccccc1>>COc1cc2c(=O)n(COC(=O)C(C)(C)C)cnc2cc1OCc1ccccc1,,CCOC(C)=O,CN(C)C=O,Cl,[H-].[Na+],test
US20070099901A1,CON=CCCCn1c(C)nc2c(N)nc3ccccc3c21>>CONCCCCn1c(C)nc2c(N)nc3ccccc3c21,,CC(=O)O,CCO,[BH3-]C#N.[Na+],,test
US20110275657A1,CCOC(=O)C1(C2CCCCC2)CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)OC(C)(C)C)CC1>>CCOC(=O)C1(C2CCCCC2)CCN(C(=O)[C@H](N)Cc2ccc(Cl)cc2)CC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100168421A1,COC(=O)C1(NC(=O)OCc2ccccc2)CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(CO)(NC(=O)OCc2ccccc2)CC1,,C1CCOC1,O,[BH4-].[Li+],,test
USRE029836,CCOC(=O)C1=C(O)c2ccccc2S(=O)(=O)N1C.Nc1ccon1>>CN1C(C(=O)Nc2ccon2)=C(O)c2ccccc2S1(=O)=O,,Cc1ccccc1C,,,,test
US20160052897A1,CC(C)(C)OC(=O)N1CCOc2c(Br)cc(C(F)(F)F)cc21.CC(C)[Si](c1ncc(B2OC(C)(C)C(C)(C)O2)o1)(C(C)C)C(C)C>>CC(C)(C)OC(=O)N1CCOc2c(-c3cnco3)cc(C(F)(F)F)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20080027068A1,CNN=CC(C)=O.O=CC(=O)c1ccc(Cl)c(Cl)c1>>CC(=O)c1nn(C)c(-c2ccc(Cl)c(Cl)c2)c1O,,CC(=O)O,,,,test
US05576322,Clc1ccc2nc(Cl)nc(NCc3ccc4c(c3)OCO4)c2c1.OC1COC(c2ccccc2)OC1>>Clc1ccc2nc(OC3COC(c4ccccc4)OC3)nc(NCc3ccc4c(c3)OCO4)c2c1,,O,,CN(C)C=O,[H-].[Na+],test
US05162521,CC(O)=C(C(=O)OCc1ccc([N+](=O)[O-])cc1)N1C(=O)[C@@H](NC(=O)COc2ccccc2)[C@H]1SS(=O)(=O)c1ccc(C)cc1.CS(=O)(=O)CS(=O)(=O)Cl>>CC(OS(C)(=O)=O)=C(C(=O)OCc1ccc([N+](=O)[O-])cc1)N1C(=O)[C@@H](NC(=O)COc2ccccc2)[C@H]1SS(=O)(=O)c1ccccc1C,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20050159462A1,C[C@H](O[Si](C)(C)C(C)(C)C)[C@H](CCc1cccc2oc(-c3ccc(Cl)cc3)nc12)OS(C)(=O)=O.NC(=O)c1c[nH]cn1>>C[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CCc1cccc2oc(-c3ccc(Cl)cc3)nc12)n1cnc(C(N)=O)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20130026426A1,COc1ccc(B(O)O)cc1.Cc1ccc(-n2c3ccc(Br)cc3c3cc(-c4ccccc4)ccc32)cc1>>COc1ccc(-c2ccc3c(c2)c2cc(-c4ccccc4)ccc2n3-c2ccc(C)cc2)cc1,,CCO,,Cc1ccccc1,,test
US20050054639A1,Nc1ccccc1[N+](=O)[O-].O=C(Br)CBr>>O=C(CBr)Nc1ccccc1[N+](=O)[O-],,ClCCl,,c1ccncc1,,test
US20110059940A1,CC(C)(C)OC(=O)c1ccc(CN(C(C(N)=O)c2cc(F)cc(F)c2)S(=O)(=O)c2ccc(Cl)cc2)cc1>>NC(=O)C(c1cc(F)cc(F)c1)N(Cc1ccc(C(=O)O)cc1)S(=O)(=O)c1ccc(Cl)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110294758A1,CC(C)Oc1cc(Oc2ccc(P(=O)(O)O)cc2)cc(C(=O)Nc2nccs2)c1.CC(I)OC(=O)C(C)(C)C>>CC(C)Oc1cc(Oc2ccc(P(=O)(O)OC(C)OC(=O)C(C)(C)C)cc2)cc(C(=O)Nc2nccs2)c1,,CC#N,ClCCl,CCN(C(C)C)C(C)C,,test
US20050054640A1,CCOCc1nc2c(N)nc3ccccc3c2n1NCCCNC(=O)OC(C)(C)C>>CCOCc1nc2c(N)nc3ccccc3c2n1NCCCN,,CCO,O,Cl,[Na+].[OH-],test
US20130029973A1,CCOP(=O)(Cc1ccc([N+](=O)[O-])cc1)OCC.COC(=O)c1ccc(C=O)cc1>>COC(=O)c1ccc(/C=C/c2ccc([N+](=O)[O-])cc2)cc1,,CO,,C[O-].[Na+],,test
US20050054701A1,CC(C)(C)OC(=O)c1cnc(Cl)c(Cl)c1Nc1ccc(Br)cc1Cl.CC(O)CN>>CC(O)CNc1ncc(C(=O)OC(C)(C)C)c(Nc2ccc(Br)cc2Cl)c1Cl,,CC#N,CCOC(C)=O,CCN(CC)CC,,test
US05684029,CCCCCN(C(=O)NC)c1ccc2nc(CCCC)n(Cc3ccc(-c4ccccc4-c4nnnn4C(c4ccccc4)(c4ccccc4)c4ccccc4)cc3)c2c1>>CCCCCN(C(=O)NC)c1ccc2nc(CCCC)n(Cc3ccc(-c4ccccc4-c4nnn[nH]4)cc3)c2c1,,CCO,,Cl,,test
US20080221132A1,CCNCCN.O=C(Cl)c1ccc([N+](=O)[O-])cc1>>CCNCCNC(=O)c1ccc([N+](=O)[O-])cc1,,CCOCC,,CCN(CC)CC,,test
US20080085895A1,CC(C)(C)OC(=O)NC[C@H]1COCc2nc3cnc4ccccc4c3n21.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)OC(=O)NC[C@H]1COCc2nc3c[n+]([O-])c4ccccc4c3n21,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US04374136,BrCCCBr.Oc1ccc(-c2ccc(Cl)cc2)cc1>>Clc1ccc(-c2ccc(OCCCBr)cc2)cc1,,CO,,[Na],C[O-].[Na+],test
US07335655B2,CC(C)Cn1c(N)c(N)c(=O)n(CC(C)C)c1=O.CCOC(=O)COc1cc(C(=O)O)nn1C>>CC(C)Cn1c(=O)c2[nH]c(-c3cc(OCC(=O)O)n(C)n3)nc2n(CC(C)C)c1=O,,CO,,CCN=C=NCCCN(C)C,,test
US20120101064A1,COC(=O)c1ccc(C#N)c(-c2cncc3c2ccn3C(=O)OC(C)(C)C)c1.COc1ncc2c(ccn2COCC[Si](C)(C)C)c1Br>>COC(=O)c1ccc(C#N)c(-c2c(OC)ncc3c2ccn3COCC[Si](C)(C)C)c1,,O,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20010031759A1,CCc1nc(C)cc(=O)n1CCOc1ccc([N+](=O)[O-])cc1>>CCc1nc(C)cc(=O)n1CCOc1ccc(N)cc1,[Pd],C1COCCO1,,[H][H],,test
US04145337,CC(=O)O.CCO.CN(C)C=O.CO.COC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)[C@@H](C)OC(C)(C)C>>COC(=O)[C@H](COC(C)(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)OCc1ccccc1)[C@@H](C)OC(C)(C)C)[C@@H](C)OC(C)(C)C,[Pd],CO,,,,test
US04469695,COc1ccc(C(=O)CN2CCN(c3cccccc3=O)CC2)cc1OC>>COc1ccc(C(O)CN2CCN(c3cccccc3=O)CC2)cc1OC,,CO,ClC(Cl)Cl,[BH4-].[Na+],,test
US20030203890A1,O=S(=O)(Cl)Cc1ccccc1.OC[C@@H]1CCCN1>>O=S(=O)(Cc1ccccc1)N1CCC[C@H]1CO,,ClCCl,O,CCN(CC)CC,,test
US03975535,CC(=O)c1ccccc1C(=O)O.CCOC(=O)C(Br)C(=O)OCC>>Cc1c(C(=O)O)oc(=O)c2ccccc12,,CCO,,[K+].[OH-],,test
US20040157886A1,Nc1ccc2oc(=O)[nH]c2c1.O=C(O)C(=O)N1CCC(Cc2ccc(F)cc2)CC1>>O=C(Nc1ccc2oc(=O)[nH]c2c1)C(=O)N1CCC(Cc2ccc(F)cc2)CC1,,O,,,,test
US05081138,COC(=O)CCC(=O)CSC.NN(Cc1ccc(Cl)cc1)c1ccc(F)cc1>>CSc1c(CCC(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(F)cc12,,CC(C)(C)O,,Cl,,test
US20160237059A1,CC(O)=S.CCOC(=O)C(NC(C)=O)C(=O)CBr>>CCOC(=O)[C@@H](NC(C)=O)C(=O)CSC(C)=O,,CCO,,O,[K+].[OH-],test
US05646308,CNC(=S)C1c2cc([N+](=O)[O-])ccc2OC2(CCOCC2)C1O>>CNC(=S)C1=CC2(CCOCC2)Oc2ccc([N+](=O)[O-])cc21,,O,,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,test
US20090181942A1,CCOC(=O)C[C@H]1O[C@H](c2cccc(OC)c2OC)c2cc(OC(F)(F)F)ccc2-n2c1nnc2C(F)(F)F>>COc1cccc([C@H]2O[C@H](CC(=O)O)c3nnc(C(F)(F)F)n3-c3ccc(OC(F)(F)F)cc32)c1OC,,C1COCCO1,,Cl,,test
US20160024049A1,Cn1ccnc1C=O.c1ccc(-c2ccncc2)c(OC2CCNCC2)c1>>Cn1ccnc1CN1CCC(Oc2ccccc2-c2ccncc2)CC1,,CC#N,CC(=O)O,O=C([O-])[O-].[Na+].[Na+],,test
US20120258949A1,COC(=O)/C=C/c1ccc2c(c1)C(=O)CC1(CCCN(Cc3ccccc3)C1)O2>>O=C(O)/C=C/c1ccc2c(c1)C(=O)CC1(CCCN(Cc3ccccc3)C1)O2,,CC(=O)O,,Cl,,test
US04965257,C#C[Si](C)(C)C.CCC12COC(c3ccc(I)cc3)(OC1)OC2>>CCC12COC(c3ccc(C#C[Si](C)(C)C)cc3)(OC1)OC2,,CCNCC,,,,test
US20090181948A1,CSC(=C(C#N)C#N)N1CCC(N2CCCCC2)CC1.NC1CCN(Cc2ccccc2)CC1>>N#CC(C#N)=C(NC1CCN(Cc2ccccc2)CC1)N1CCC(N2CCCCC2)CC1,,CCCCCC,,CC(C)OC(C)C,,test
US05057614,CSc1c(C2=C(c3cn(C)c4ccccc34)C(=O)OC2=O)c2ccccc2n1C.N>>CSc1c(C2=C(c3cn(C)c4ccccc34)C(=O)NC2=O)c2ccccc2n1C,,N,,CN(C)C=O,,test
US20020037894A1,O=[N+]([O-])c1ccc2c(c1)S(=O)(=O)NC1CCCN21>>Nc1ccc2c(c1)S(=O)(=O)NC1CCCN21,[Pd],CO,,O=C[O-].[NH4+],,test
US20040229900A1,O=[N+]([O-])c1cccc(S(=O)(=O)OC[C@@H]2CO2)c1.Oc1ccc(-n2ccnc2)cc1>>c1cn(-c2ccc(OCC3CO3)cc2)cn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110053908A1,CS(=O)(=O)N(c1cc(F)cc(C(=O)O)c1)C1CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1.C[C@H](N)CO>>CC(CO)NC(=O)c1cc(F)cc(N(C2CN(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)C2)S(C)(=O)=O)c1,,C1CCOC1,,CC(C)COC(=O)Cl,CCN(CC)CC,test
US20070259877A1,CCOc1ccc(NS(=O)(=O)c2ccc(I)cc2)cc1N1C[C@H](C)N[C@H](C)C1.OB(O)c1cccs1>>CCOc1ccc(NS(=O)(=O)c2ccc(-c3cccs3)cc2)cc1N1C[C@H](C)N[C@H](C)C1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,Cc1ccccc1,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20040229858A1,CC#N.CCN(CC)CC.CCN=C=NCCCN(C)C.COC(=O)c1ccc(OCC2CSCN2C(=O)OC(C)(C)C)cc1.Cl.ClCCl.O=C(O)C(F)(F)F.On1nnc2ccccc21>>COC(=O)c1ccc(OCC2CSCN2C(=O)Cc2ccc(NC(=O)Nc3ccccc3Cl)c(OC)c2)cc1,,CC#N,ClCCl,C1CCOC1,,test
US20070135467A1,COc1cc(C(=N[S@](=O)C(C)(C)C)c2cc(F)cc(OC(F)(F)C(F)F)c2)ccc1F.Cl[Mg]Cc1ccccc1>>COc1cc(C(Cc2ccccc2)(N[S@](=O)C(C)(C)C)c2cc(F)cc(OC(F)(F)C(F)F)c2)ccc1F,,ClCCl,,CCOCC,FB(F)F,test
US20100069504A1,CC(C)(C)OC(=O)NC1CCc2cccc(Br)c2CC1=O.OB(O)c1ccccc1>>CC(C)(C)OC(=O)NC1CCc2cccc(-c3ccccc3)c2CC1=O,,CCOC(C)=O,COCCOC,[Cs+].[F-],,test
US05081287,OCCCC(Br)CC(F)(F)Br>>OCCCCCC(F)(F)Br,[Pd],CCO,,,,test
US20130225553A1,COC(=O)c1cc2c(cc1C)[nH]c(=O)c1cnn(C3CCOCC3)c12>>Cc1cc2[nH]c(=O)c3cnn(C4CCOCC4)c3c2cc1C(=O)O,,CO,,[Na+].[OH-],,test
US20100216839A1,CC=C1C[C@H](NC(=O)OC(C)(C)C)CN(C(=O)OCc2ccccc2)C1.O=[N+]([O-])c1cnccc1Cl>>CC[C@@H]1C[C@H](NC(=O)OC(C)(C)C)CN(c2ccncc2[N+](=O)[O-])C1,[Pd],CCO,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20140243404A1,CC(=O)OC(C)=O.CC(C)=CCC/C(C)=C\CC/C(C)=C/CO>>CC(=O)OC/C=C(\C)CC/C=C(/C)CCC=C(C)C,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20030045727A1,CNc1ccccc1.C[C@H]1CO1>>C[C@H](O)CN(C)c1ccccc1,,CCOCC,,,,test
US05250690,Nc1ccc(OC(F)(F)C(F)Br)cc1>>Nc1ccc(OC(F)=CF)cc1,[Zn],CC(=O)O,,Cl,[Na+].[OH-],test
US20120196872A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1NC(c2cc(F)cc(F)c2)CN[C@H]1CC1CCCCCC1>>CC(C)(C)OC(=O)N1CC(c2cc(F)cc(F)c2)NC(=O)[C@@H]1CC1CCCCCC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US04675333,CCCc1c(O)ccc(C(C)=O)c1O.O=[N+]([O-])c1ccc(OCCCCl)cc1>>CCCc1c(OCCCOc2ccc([N+](=O)[O-])cc2)ccc(C(C)=O)c1O,,CN(C)C=O,,[H-].[Na+],,test
US20110263612A1,Nc1ccc(-c2cc3c(cc2Br)CCO3)cn1.O=C(Cl)c1ccccc1F>>O=C(Nc1ccc(-c2cc3c(cc2Br)CCO3)cn1)c1ccccc1F,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US04129654,CN=C=O.NC1CCCCC1>>CNC(=O)NC1CCCCC1,,CCOCC,,,,test
US04684653,CCOC(=O)CC[C@H](NC(=O)c1ccc(CCc2cnc3nc(N)nc(N)c3c2)cc1)C(=O)OCC>>Nc1nc(N)c2cc(CCc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)cnc2n1,,CO,,CC(=O)O,[Na+].[OH-],test
US08993586B2,COc1ccc(CNc2nccc3ccc(C(=O)N4CCC5(CC4)Cc4cn(C(C)(C)C)nc4C(=O)N5)cc23)cc1>>CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccnc(N)c4c3)CC1)C2,,O=C(O)C(F)(F)F,,COc1ccccc1,,test
US20050267104A1,CC(C)C(=O)O.CCSC(=O)OCI>>CCSC(=O)OCOC(=O)C(C)C,,ClCCl,,O,,test
US20070232645A1,CC(=O)Nc1ccc(Sc2ccc(C)cc2Nc2ccnc3nc(Cl)ccc23)cc1.CCOC(=O)CC(=O)OCC>>CCOC(=O)C(C(=O)OCC)c1ccc2c(Nc3cc(C)ccc3Sc3ccc(NC(C)=O)cc3)ccnc2n1,,C1CCOC1,,[H-].[Na+],,test
US20120157451A1,CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3cc(C4CCN(C(=O)OC(C)(C)C)CC4)nn3c2)c1F>>CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3cc(C4CCNCC4)nn3c2)c1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070049587A1,N#Cc1cc(N2CCOCC2=O)ccc1[N+](=O)[O-]>>N#Cc1cc(N2CCOCC2=O)ccc1N,[Pd],C1CCOC1,,,,test
US20020013341A1,CCOC(=O)CC(C)NCc1ccccc1.COC(=O)CBr>>CCOC(=O)CC(C)N(CC(=O)OC)Cc1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110136763A1,CCOC(=O)CC1OB(O)c2cc(O)cc(C)c21.COC(=O)c1cnc(Cl)cn1>>CCOC(=O)CC1OB(O)c2cc(Oc3cnc(C(=O)OC)cn3)cc(C)c21,,CN(C)C=O,,Cl,[H-].[Na+],test
US20090069291A1,O=P(O)(O)O.c1ccc2c(c1)N=C(N1CCNCC1)c1ccccc1S2>>O=P(O)(O)O.c1ccc2c(c1)N=C(N1CCNCC1)c1ccccc1S2,,CC#N,,,,test
US05362725,CCOC(=O)COCCCl.c1ccc2c(c1)Cc1ccccc1N1CCNCC21>>CCOC(=O)COCCN1CCN2c3ccccc3Cc3ccccc3C2C1,,CC(=O)CC(C)C,,[I-].[Na+],,test
US20150232435A1,CC(C)(C)c1nc(N2CCN(CCCCN)CC2)cc(C(F)(F)F)n1.COc1ccc(N2CCNCC2)cc1.O=C(n1ccnc1)n1ccnc1>>COc1ccc(N2CCN(C(=O)NCCCCN3CCN(c4cc(C(F)(F)F)nc(C(C)(C)C)n4)CC3)CC2)cc1,,CO,ClC(Cl)Cl,,,test
US20060293376A1,COC(OC)[C@@]1(C)Oc2ccc(N)cc2[C@H](n2c(=NC#N)[nH]c3ccccc32)[C@H]1O.O=C(Cl)c1ccccc1>>COC(OC)[C@@]1(C)Oc2ccc(NC(=O)c3ccccc3)cc2[C@H](n2c(=NC#N)[nH]c3ccccc32)[C@H]1O,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20030195211A1,O=c1c2cc(Br)ccc2nc(CCl)n1-c1ccccc1Cl.Sc1ncnc2nc[nH]c12>>O=c1c2cc(Br)ccc2nc(CSc2ncnc3[nH]cnc23)n1-c1ccccc1Cl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120165347A1,CC(=O)C(N)=S.COC1CCC2(CC1)Cc1ccc(Br)cc1C2=N>>COC1CCC2(CC1)Cc1ccc(Br)cc1C21N=C(C)C(=S)N1,,CO,,,,test
US20100009975A1,CCN(CCN1CCSc2ccc(NC(=N)c3cccs3)cc21)C(=O)OC(C)(C)C>>CCNCCN1CCSc2ccc(NC(=N)c3cccs3)cc21,,CO,,Cl,,test
US04435403,C=O.CCOC(=O)[C@@H](N)C(COC)c1c[nH]c2ccccc12>>CCOC(=O)c1ncc2[nH]c3ccccc3c2c1COC,,c1ccccc1,,O,,test
US04916145,C1=NC(CC/C=C/c2cncc3ccccc23)c2ccccc21>>NCC/C=C/c1cncc2ccccc12,,CCO,,NN,O,test
US20100040753A1,CO[Na].O=C(CO)c1ccccc1.O=Cc1ccncc1>>O=C(C=Cc1ccccc1)c1ccccc1,,C1CCOC1,,,,test
US04087551,CC1(C)C2CCC1(CN)CC2.O=Cc1ccccc1>>CC1(C)C2CCC1(C(N)=Cc1ccccc1)CC2,,Cc1ccccc1,,O,,test
US20080207900A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)[C@H]1CC[C@@H](c2ccc(Cl)cc2)N1>>CCOC(=O)[C@H]1CC[C@@H](c2ccc(Cl)cc2)N1C(=O)OC(C)(C)C,,CCN(CC)CC,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,test
US20050154224A1,CCOC(=O)C[C@H](O)CCl.[C-]#N>>N#CC[C@@H](O)CC(=O)O,,CC(=O)O,,[C-]#N.[Na+],,test
US20160185779A1,Nc1ccccc1.O=C(n1ccnc1)n1ccnc1.c1ccc(-c2n[nH]c3c2CNCC3)cc1>>O=C(Nc1ccccc1)N1CCc2[nH]nc(-c3ccccc3)c2C1,,ClCCl,,O,,test
US20070004753A1,CNC(=O)c1ccc(N)cc1F.C[Si](C)(C)C#N.O=C1CCCC1>>CNC(=O)c1ccc(NC2(C#N)CCCC2)cc1F,,CCOC(C)=O,,,,test
US04833144,O=C(OO)c1cccc(Cl)c1.O=c1c2ccccc2nc(SCc2ccncc2)n1-c1ccccc1>>O=c1c2ccccc2nc(S(=O)Cc2ccncc2)n1-c1ccccc1,,ClC(Cl)Cl,,,,test
US20140221311A1,CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1F>>Nc1cnc(-c2ccc(-c3ccccc3S(N)(=O)=O)c(F)c2F)cn1,,O=C(O)C(F)(F)F,,,,test
US20090105219A1,CC(C)(C)OC(=O)Cn1cc(CC#N)c2c(N)cccc21.O=C1CCC(=O)N1Cl>>CC(C)(C)OC(=O)Cn1cc(CC#N)c2c(N)c(Cl)ccc21,,ClCCl,,,,test
US20150274720A1,CC(C)(C)OC(=O)N1CCN(c2nc(-c3ccnc4c3c(-c3ccccc3)cn4S(=O)(=O)c3ccccc3)nc3cncc(C4CC4)c23)CC1>>CC(C)(C)OC(=O)N1CCN(c2nc(-c3ccnc4[nH]cc(-c5ccccc5)c34)nc3cncc(C4CC4)c23)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US03935214,CCN(CC)C(C)N1CCNCC1c1ccccc1.ClCc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1>>CCN(CC)CCN1CCN(Cc2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)CC1c1ccccc1.Cl,,CCC(C)=O,,CCN(CC)CC,,test
US20130131036A1,Brc1ccccn1.Cc1cccc(C2(C#N)CCCO2)c1.O=S(=O)(O)O>>Cc1cccc(C2(C(=O)c3ccccn3)CCCO2)c1,,C1CCOC1,,[Li]CCCC,,test
US20060270632A1,Cc1ccc(NC2CCN(CCC(O[Si](C)(C)C(C)(C)C)C3CCCCC3)CC2)nc1.O=C(Cl)c1ccco1>>Cc1ccc(N(C(=O)c2ccco2)C2CCN(CCC(O[Si](C)(C)C(C)(C)C)C3CCCCC3)CC2)nc1,,ClCCl,,CCN(CC)CC,,test
US20070032494A1,COC(=O)Cc1cc(Cl)c(O)c(Cl)c1>>OCCc1cc(Cl)c(O)c(Cl)c1,,C1CCOC1,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20100190829A1,CC(C)(C)OC(=O)N1CCCC(N(CCCN=[N+]=[N-])c2cccc(Cl)c2)C1>>CC(C)(C)OC(=O)N1CCCC(N(CCCN)c2cccc(Cl)c2)C1,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US05707976,C[Si](C)(C)n1cncn1.Fc1ccc(C2(CCl)CO2)c(F)c1.[K]n1cncn1>>C[Si](C)(C)OC(CCl)(Cn1cncn1)c1ccc(F)cc1F,,CN(C)C=O,O,CC(=O)O,,test
US20100130495A1,COC(C(=O)O)c1ccccc1.O=C(n1ccnc1)n1ccnc1>>COC(C(=O)n1ccnc1)c1ccccc1,,ClCCl,,,,test
US20110021479A1,CC(=O)c1ccc(OCC2CC2)cc1C.O=C1CCC(=O)N1Br>>CC(=O)c1cc(Br)c(OCC2CC2)cc1C,,CN(C)C=O,,O,,test
US20060084640A1,CCN1CCCC1CN.C[Si](C)(C)CCOCn1c(N2CCN(c3ncccc3C(F)(F)F)CC2)nc(C(=O)O)c1-c1ccc(C(F)(F)F)cc1>>CCN1CCCC1CNC(=O)c1nc(N2CCN(c3ncccc3C(F)(F)F)CC2)[nH]c1-c1ccc(C(F)(F)F)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20070249670A1,COC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(OC)cc2)cc1N)[C@@H](C)OC(C)(C)C.Cc1cc(C)c(N=C=O)c(C)c1>>COC(=O)[C@@H](NC(=O)c1ccc(-c2ccc(OC)cc2)cc1NC(=O)Nc1c(C)cc(C)cc1C)[C@@H](C)OC(C)(C)C,,c1ccncc1,,CCCCCC,CCOC(C)=O,test
US20120295915A1,CC(=O)Cl.c1ccc(-c2ccc(-c3nc4cnccc4n3C[C@@H]3CCNC3)cc2)cc1>>CC(=O)N1CC[C@@H](Cn2c(-c3ccc(-c4ccccc4)cc3)nc3cnccc32)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20110172245A1,CC(C)(C#N)c1cccc(C(=O)Nc2cccc(Oc3cc4sc(N)nc4cc3F)c2)c1.O=C(Cl)C1CC1>>CC(C)(C#N)c1cccc(C(=O)Nc2cccc(Oc3cc4sc(NC(=O)C5CC5)nc4cc3F)c2)c1,,CCOC(C)=O,c1ccncc1,,,test
US20080038242A1,COCCl.O=Cc1ccc(F)c(O)c1>>COCOc1cc(C=O)ccc1F,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US05102667,CN(C)c1ccccc1CC(=O)O.O=C1CCC(c2ccccc2)(c2ccccc2)[C@@H]2CNC[C@H]12>>CN(C)c1ccccc1CC(=O)N1C[C@@H]2C(=O)CCC(c3ccccc3)(c3ccccc3)[C@@H]2C1,,ClCCl,,CCN(CC)CC,Cl,test
US20100099718A1,Cc1ccc(Cc2cccc(C=O)c2)s1>>Cc1ccc(Cc2cccc(CO)c2)s1,,O,,CCO,[BH4-].[Na+],test
US20130045942A1,Cl.ON=C(c1ccccc1)c1ccccc1>>Cl.NC(c1ccccc1)c1ccccc1,[Pd],CCO,,,,test
US04945100,CCCC(COS(C)(=O)=O)(OC)c1ccc(Cl)cc1Cl.c1nc[nH]n1>>CCCC(Cn1cncn1)(OC)c1ccc(Cl)cc1Cl,,CS(C)=O,,[Na],,test
US20150141400A1,O=C(OO)c1cccc(Cl)c1.O=c1[nH]c2ccc(C(F)(F)F)cc2c(=O)n1Cc1cc(Cl)ccc1Sc1ccccc1>>O=c1[nH]c2ccc(C(F)(F)F)cc2c(=O)n1Cc1cc(Cl)ccc1S(=O)c1ccccc1,,CCOC(C)=O,,,,test
US20010049371A1,CCOc1cc(C(CC(=O)O)N2C(=O)c3cccc(NC(C)=O)c3C2=O)ccc1OC.NO>>CCOc1cc(C(CC(=O)NO)N2C(=O)c3cccc(NC(C)=O)c3C2=O)ccc1OC,,C1CCOC1,,Cl,O=C(n1ccnc1)n1ccnc1,test
US20120238564A1,CN1CCN(c2nccn3c(-c4ccnc(NC(CNC(=O)OC(C)(C)C)c5cccc(Cl)c5)n4)cnc23)CC1>>CN1CCN(c2nccn3c(-c4ccnc(NC(CN)c5cccc(Cl)c5)n4)cnc23)CC1,,CCO,,Cl,,test
US20040171881A1,CCCCN1CCCc2ccc(C(=O)O)cc21.CCc1cccc(CNC[C@@H](O)[C@@H](N)Cc2cc(F)cc(F)c2)c1>>CCCCN1CCCc2ccc(C(=O)N[C@@H](Cc3cc(F)cc(F)c3)[C@H](O)CNCc3cccc(CC)c3)cc21,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20140228343A1,CC(C)(C)OC(=O)Nc1cccc(OCC(O)CN2CCc3ccccc3C2)c1>>Nc1cccc(OCC(O)CN2CCc3ccccc3C2)c1,,CCOC(C)=O,,Cl,,test
US20150011548A1,CCOC(=O)CBr.c1nc[nH]n1>>CCOC(=O)Cn1cncn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04008066,CN(C)C=O.CNC(=O)CNc1c(C)cccc1C.O=C(Cl)CCl>>Cc1cccc(C)c1N(CC(=O)N(C)C)C(=O)CCl,,Clc1ccccc1,,Cl,,test
US05602185,O=S(=O)(Cl)c1ccc(I)cc1.[F-]>>O=S(=O)(F)c1ccc(I)cc1,,CC(C)=O,,O,,test
US20090286812A1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Cl)ncnc32)CC1.N#Cc1ccc(O)cc1F>>CC(C)(C)OC(=O)N1CCC(n2ncc3c(Oc4ccc(C#N)c(F)c4)ncnc32)CC1,,CN(C)C=O,,,,test
US20070105904A1,O=[N+]([O-])/C=C/c1cccc(OCc2ccccn2)c1>>O=[N+]([O-])CCc1cccc(OCc2ccccn2)c1,,CS(C)=O,,CC(=O)O,[BH4-].[Na+],test
US20030105098A1,Clc1nc(Cl)c2ncn(C3CCCC3)c2n1.NNc1ccccc1Cl>>Clc1nc(NNc2ccccc2Cl)c2ncn(C3CCCC3)c2n1,,CCN(CC)CC,,,,test
US20040180901A1,C1CNCCN1.Fc1ccc(-c2cnc(Cl)cn2)cc1>>Fc1ccc(-c2cnc(N3CCNCC3)cn2)cc1,,CC(=O)N(C)C,,,,test
US20140088101A1,COC(=O)C=CC(C(=O)OC)=C(C)NCC1CCCC1.O=C1CCC(=O)N1Br>>COC(=O)c1cc(Br)c(=O)n(CC2CCCC2)c1C,,CO,,C[O-].[Na+],,test
US05576335,COc1ccc(NC(=O)Oc2ccccc2)c([N+](=O)[O-])c1.NC1CCCC1>>COc1ccc(NC(=O)NC2CCCC2)c([N+](=O)[O-])c1,,Cc1ccccc1C,,,,test
US20090042929A1,O=C(CS(=O)c1cccs1)C12CC3CC(CC(C3)C1)C2.O=C(OO)c1cccc(Cl)c1>>O=C(CS(=O)(=O)c1cccs1)C12CC3CC(CC(C3)C1)C2,,ClCCl,,,,test
US20110218192A1,N#Cc1cccc(B(O)O)c1.O=C1CC(c2cccnc2)Oc2ccc(Br)cc21>>N#Cc1cccc(-c2ccc3c(c2)C(=O)CC(c2cccnc2)O3)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070003539A1,CO.O=C(Cl)c1cc(S(=O)(=O)Cl)cc(S(=O)(=O)Cl)c1>>COC(=O)c1cc(S(=O)(=O)Cl)cc(S(=O)(=O)Cl)c1,,ClCCl,,,,test
US20150087825A1,CC(C)(C)OC(=O)NC1=NC(C)(c2cc(N=[N+]=[N-])ccc2F)CC2(CCOCC2)O1>>CC(C)(C)OC(=O)NC1=NC(C)(c2cc(N)ccc2F)CC2(CCOCC2)O1,[Pd],CCO,,,,test
US20120053201A1,CCCCS(=O)(=O)Cl.COC(=O)c1ccc2c(n1)CCNC2>>CCCCS(=O)(=O)N1CCc2nc(C(=O)OC)ccc2C1,CN(C)c1ccncc1,CN(C)C=O,,Cl,,test
US20130059834A1,CN(C)CC(C)(C)N.Cc1ccc2c(-c3cnc4[nH]cc(C(=O)O)c4n3)n[nH]c2c1>>Cc1ccc2c(-c3cnc4[nH]cc(C(=O)NC(C)(C)CN(C)C)c4n3)n[nH]c2c1,CN(C)c1ccncc1,CN(C)C=O,,O,,test
US05677305,CCCn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(F)cc21.O=[N+]([O-])c1cnccc1O>>CCCn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(-n3ccc(=O)c([N+](=O)[O-])c3)cc21,,CS(C)=O,,[K+].[OH-],,test
US20080242699A1,COc1ccc(Cn2cc(Cl)c3cc(O[C@H]4CC[C@@H](NC(C)=O)CC4)c(S(N)(=O)=O)cc3c2=O)cc1>>COc1ccc(Cn2cc(Cl)c3cc(O[C@@H]4CC[C@H](N)CC4)c(S(N)(=O)=O)cc3c2=O)cc1,,CCO,,Cl,,test
US20090156646A1,CC(C)(C)[Si](C)(C)Oc1ccccc1-c1cc(-c2cccc([N+](=O)[O-])c2)c(C#N)c(N)n1.O=C(Cl)c1ccccc1>>NC(=O)c1ccccc1,,c1ccncc1,,,,test
US20080262042A1,CC(=O)c1cccc(S(=O)(=O)n2cc(CN(C)C(=O)OC(C)(C)C)cc2-c2cccnc2F)c1.Cl>>CNCc1cc(-c2cccnc2F)n(S(=O)(=O)c2cccc(C(C)=O)c2)c1.Cl,,CCO,,CCOC(C)=O,,test
US20090036450A1,O=C(O)c1cc(NC(=O)c2cc(F)c(F)cc2Cl)[nH]n1.O=C(n1ccnc1)n1ccnc1>>O=C(O)c1cc(NC(=O)c2cc(F)c(F)cc2Cl)[nH]n1.c1c[n-]cn1,,C1CCOC1,O,CCCCCC,CCOC(C)=O,test
US03935223,CCOC(=O)CC(=N)N.COc1ncnc(OC)c1C=O.O=C1CCCC(=O)C1>>CCOC(=O)C1=C(N)NC2=C(C(=O)CCC2)C1c1c(OC)ncnc1OC,,CCO,,,,test
US20090312336A1,CC[C@@H]1CN(CC)c2cnc(Nc3ccc(C(=O)OC)cc3OC)nc2N1C1CCCC1>>CC[C@@H]1CN(CC)c2cnc(Nc3ccc(C(=O)O)cc3OC)nc2N1C1CCCC1,,O,,Cl,,test
US20050124626A1,CCOC(=O)CC(C)=O.Nc1ccccc1N1CCN(C(=O)C(F)(F)F)CC1>>CCOC(=O)C=C(C)Nc1ccccc1N1CCN(C(=O)C(F)(F)F)CC1,,Cc1ccccc1,,CC(=O)O,,test
US08309542B2,CN1CCc2cc(C(=O)N3CC[C@@H](NC(=O)OC(C)(C)C)C3)ccc2C1>>CN1CCc2cc(C(=O)N3CC[C@@H](N)C3)ccc2C1,,C1CCOC1,,Cl,,test
US05180735,COC1C(=O)CCC(O)(CSCc2ccccc2CO)C1C1(C)OC1CC=C(C)C.[NH4+]>>COC1C(N)CCC(O)(CSCc2ccccc2CO)C1C1(C)OC1CC=C(C)C,,CO,,[BH3-]C#N.[Na+],,test
US06090805,CC(C)(C)OC(=O)N1CCC(Oc2ccc(CC(=O)N3CCC(N4C(=O)OCc5ccccc54)CC3)c(OCC(F)(F)F)c2)CC1>>O=C(Cc1ccc(OC2CCNCC2)cc1OCC(F)(F)F)N1CCC(N2C(=O)OCc3ccccc32)CC1,,CCOC(C)=O,,Cl,,test
US20100029611A1,O.O=Cc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1>>O=C(O)c1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1,,CC(C)(C)O,O,CC=C(C)C,[Na+].[O-]Cl,test
US20150011773A1,CC(C)(C)OC(=O)N[C@@H](C[C@H](Cc1ccc(O)cn1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C.FCCI>>CC(C)(C)OC(=O)N[C@@H](C[C@H](Cc1ccc(OCCF)cn1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04476307,COc1ccc(-n2ccc3ccccc32)cc1F.O=C1CCC(=O)N1Cl>>COc1ccc(N2C(=O)Cc3ccccc32)cc1F,,ClCCl,,,,test
US04477553,CC=O.Cc1c(O)cccc1O>>CC1(CC=O)C(O)=CC=CC1O,Cl,O,,CCO,,test
US20150099732A1,CC1(C)OB(c2ccc(CBr)cc2)OC1(C)C.Cc1nc2ccccc2[nH]1>>Cc1nc2ccccc2n1Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1,,CC(C)=O,O,[I-].[K+],,test
US20100029629A1,CN(C)C(=O)Cc1c[nH]c2cccnc12>>CN(C)CCc1c[nH]c2cccnc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150344429A1,CC(C)(C)/C=N/S(=O)C(C)(C)C.Cc1nnc(Br)o1>>Cc1nnc(C(NS(=O)C(C)(C)C)C(C)(C)C)o1,,C1CCOC1,Cc1ccccc1,CC(C)[Mg]Cl,,test
US20090306089A1,CO.COC(OC)OC.O=Cc1cnc(I)c(Cl)c1>>COC(OC)c1cnc(I)c(Cl)c1,,CO,,Cl,ClCCl,test
US20100286115A1,COC(=O)c1cc(OCc2c(-c3ccc(F)cc3)noc2C)n[nH]1>>Cc1onc(-c2ccc(F)cc2)c1COc1cc(C(=O)O)[nH]n1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20150329538A1,COC(=O)c1cc(Br)cn1CCBr.COc1ccc(CN)c(OC)c1>>COc1ccc(CN2CCn3cc(Br)cc3C2=O)c(OC)c1,,CS(C)=O,,,,test
US20130029980A1,Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCCCc3ccccc3)c2cc1Cl.NC1CC1>>Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(CCCCc3ccccc3)c2cc1NC1CC1,,CN1CCCC1=O,,,,test
US20160108056A1,C=CS(=O)(=O)Nc1ccc2sc(C(=O)Nc3cc(Cl)cc(C(C)(C)c4cc(OC(C)C)cc(OC(F)(F)F)c4)c3)cc2c1.CNC>>CC(C)Oc1cc(OC(F)(F)F)cc(C(C)(C)c2cc(Cl)cc(NC(=O)c3cc4cc(NS(=O)(=O)CCN(C)C)ccc4s3)c2)c1,,C1CCOC1,,,,test
US20040063691A1,Cc1ccccc1-c1nc(C(=O)N2CCC(O)(c3ccccc3)CC2)cn1-c1ccc(Cl)cc1>>Cc1ccccc1-c1nc(C(=O)N2CC=C(c3ccccc3)CC2)cn1-c1ccc(Cl)cc1,,CCOCC,ClCCl,Cl,,test
US05661108,CCOC(=O)Nc1cc(N(Cc2cccc(Cl)c2)C(=O)C(F)(F)F)c(N)cc1F>>CCOC(=O)Nc1cc2c(cc1F)nc(C(F)(F)F)n2Cc1cccc(Cl)c1,,Cc1ccccc1,,,,test
US05733914,ClCCCc1ccccc1.Nc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)[nH]c2n1>>Nc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(CCCc3ccccc3)c2n1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US04873255,C=CC(=O)OCC.CC1(COc2ccc(N)cc2)CCc2ccccc2O1.Cl>>CCOC(=O)C(Cl)Cc1ccc(OCC2(C)CCc3ccccc3O2)cc1,,CC(C)=O,O,O=N[O-].[Na+],,test
US04337268,CC(=O)CN(C(=O)c1ccco1)c1c(C)cccc1C.[NH3+]O>>CC(CN(C(=O)c1ccco1)c1c(C)cccc1C)=NO,,CCO,ClCCl,CCN(CC)CC,,test
US06288100B1,CCCc1nc2ccc(C(=O)c3ccccc3)cc2n1Cc1ccc(C(=O)OC)cc1>>CCCc1nc2ccc(C(=O)c3ccccc3)cc2n1Cc1ccc(C(=O)O)cc1,,CO,,[K+].[OH-],,test
US20140371278A1,O=C(O)c1cc2scnc2c(F)c1Nc1ccc(I)cc1F.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>O=c1[nH]c2cc3scnc3c(F)c2n1-c1ccc(I)cc1F,,CC(C)(C)O,,CCN(CC)CC,,test
US20090186930A1,Cc1cc(C)n(C(N)=N[N+](=O)[O-])n1.Nc1ccc(Oc2ccc(-c3c[nH]c(COc4ccccc4)n3)cc2)cc1F>>NC(=N[N+](=O)[O-])Nc1ccc(Oc2ccc(-c3c[nH]c(COc4ccccc4)n3)cc2)cc1F,,CO,,,,test
US04666906,NS(=O)(=O)c1cc(C(=O)O)cc([N+](=O)[O-])c1Oc1ccccc1>>Nc1cc(C(=O)O)cc(S(N)(=O)=O)c1Oc1ccccc1,[Pd],CCO,,[H][H],,test
US20100016401A1,CC(C)(C)OC(=O)N1C[C@H]2C[C@H]2[C@H]1CN.CCOC(=O)C(F)(F)F>>CC(C)(C)OC(=O)N1CC2CC2C1CNC(=O)C(F)(F)F,,C1CCOC1,,,,test
US20160046605A1,FC(F)(F)c1ccc(Cl)nc1Cl.FC1(F)CNC1>>FC1(F)CN(c2ccc(C(F)(F)F)c(Cl)n2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US04065456,O=C1CCc2cccc(O)c2N1.OCC(O)CCl>>O=C1CCc2cccc(OCC(O)CO)c2N1,,CO,,[K+].[OH-],,test
US05646173,CC=CCC1C(=O)c2cc(CC)ccc2C1(C)C.O=[O+][O-]>>CCc1ccc2c(c1)C(=O)C(CC=O)C2(C)C,,CO,ClCCl,,,test
US20100093788A1,Nc1ccc(-c2ccccc2C(F)(F)F)cc1[N+](=O)[O-].O=C1CCC(=O)N1Cl>>Nc1c(Cl)cc(-c2ccccc2C(F)(F)F)cc1[N+](=O)[O-],,CCOC(C)=O,,CC#N,,test
US20090023921A1,CCOC(C)=O.CCc1cc(CCC(=O)C2CCCC2)cc(CC)n1>>CCc1cc(CCC(O)(CC(=O)O)C2CCCC2)cc(CC)n1,,COC(C)(C)C,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US03997539,CN(C)Cc1c[nH]c2ccccc12.O=NN1CCNCC1>>O=NN1CCN(Cc2c[nH]c3ccccc23)CC1,,Cc1ccccc1,,,,test
US20120283271A1,CC(C)C[C@@H](C(=O)O)N1Cc2c(cccc2C(F)(F)F)C1=O.Nc1cnccn1>>CC(C)C[C@@H](C(=O)Nc1cnccn1)N1Cc2c(cccc2C(F)(F)F)C1=O,CN(C)C=O,CO,ClCCl,Cc1cccc(C)n1,O=C(Cl)C(=O)Cl,test
US20090298815A1,C=CCOC(=O)Nc1cccc(C(=O)OC)c1F.[Cl-].c1cncnc1>>C=CCOC(=O)Nc1cccc(C(=O)Cc2ccnc(Cl)n2)c1F,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20090298830A1,CO.O=C(Nc1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1)C1CCCN1C(=O)[O-]>>C[C@@]1(C(=O)Nc2ccc(-c3ccnc(Nc4ccc(N5CCOCC5)cc4)n3)cc2)CCCN1,,CCOC(C)=O,CO,C1COCCO1,Cl,test
US20080214448A1,COC(=O)CCCC(N)=O.O=C(CBr)c1ccccc1[N+](=O)[O-]>>COC(=O)CCCc1nc(-c2ccccc2[N+](=O)[O-])co1,,CO,,,,test
US20110092479A1,Brc1cnc2[nH]nc(I)c2c1.C[Si](C)(C)CCOCCl>>C[Si](C)(C)CCOCn1nc(I)c2cc(Br)cnc21,,CN(C)C=O,,[H-].[Na+],,test
US20150282482A1,COC(=O)CS.O=Cc1cc(C(=O)C(F)(F)F)ccc1F>>COC(=O)c1cc2cc(C(=O)C(F)(F)F)ccc2s1,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20060167023A1,COc1ncc2c(n1)CCN(C(=O)OC(C)(C)C)C2>>COc1ncc2c(n1)CCNC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060235222A1,CCC(O)(CC)c1ccc2onc(N)c2c1.CS(=O)(=O)Nc1cccc2cc[nH]c12>>CCC(CC)(c1ccc2onc(N)c2c1)c1c[nH]c2c(NS(C)(=O)=O)cccc12,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20080261921A1,CN(C)C(=O)C(=O)c1cc(Br)cnc1F.N>>CN(C)C(=O)C(=O)c1cc(Br)cnc1N,,CCO,,,,test
US20130303538A1,COC(=O)N1CC[C@H]2[C@@H]1CCC[C@]2(O)C#Cc1cccc(C)c1.O=C(O)CCN1CCCC1>>COC(=O)N1CC[C@@H]2[C@H]1CCC[C@]2(C#Cc1cccc(C)c1)OC(=O)CCN1CCCC1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20030100580A1,COc1ccc(Br)cc1OC.O=S(=O)(O)Cl>>COc1cc(Br)c(S(=O)(=O)Cl)cc1OC,,ClCCl,,,,test
US20080032998A1,CC1CC(OS(=O)(=O)C(F)(F)F)=CCN1C(=O)Oc1ccccc1.OB(O)c1ccccc1>>CC1CC(c2ccccc2)=CCN1C(=O)Oc1ccccc1,,C1CCOC1,,O,O=C([O-])[O-].[K+].[K+],test
US06133302,COc1ccc(Cn2nnnc2C(CC(=O)c2ccc(Cl)c(Cl)c2)Cc2ccccc2)cc1>>O=C(CC(Cc1ccccc1)c1nnn[nH]1)c1ccc(Cl)c(Cl)c1,,O,,O=C(O)C(F)(F)F,,test
US20100113462A1,CCOC(=O)C1(NC(=O)c2cccc(C)c2C=C(C)C)Cc2c(F)ccc(F)c2C1>>CC(C)=Cc1c(C)cccc1C(=O)NC1(C(=O)O)Cc2c(F)ccc(F)c2C1,,CCO,O,[K+].[OH-],,test
US20080032986A1,COc1c(F)cc(F)cc1C=O.Cc1ccc2c(N)cccc2n1>>COc1c(F)cc(F)cc1C=Nc1cccc2nc(C)ccc12,,Cc1ccccc1,,CC(=O)O,,test
US04426522,O=C(Cl)Cc1ccccc1Cl.O=C1CNN(Cc2ccc(Cl)cc2)C(=O)N1>>O=C1CN(C(=O)Cc2ccccc2Cl)N(Cc2ccc(Cl)cc2)C(=O)N1,,c1ccccc1,,,,test
US20110003833A1,COC(=O)c1cc(OCc2ccccc2)cc(Cl)n1>>OCc1cc(OCc2ccccc2)cc(Cl)n1,,C1CCOC1,CCOC(C)=O,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140113901A1,CC(C)(C)OC(=O)NC1(c2ccc(C(=O)C(Br)c3ccccc3)cc2)CCC1.Nc1nnc(Br)cc1Br>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(Br)cc(Br)nn4c3-c3ccccc3)cc2)CCC1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US07179823B1,Cc1cc(C)[nH]n1.Cc1oc(-c2ccccc2)nc1COc1ccc(CCl)cc1>>Cc1cc(C)n(Cc2ccc(OCc3nc(-c4ccccc4)oc3C)cc2)n1,,O,,C1CCOC1,[H-].[Na+],test
US20100168185A1,CC(=O)Cl.CCc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC3CC3)c2)s1>>CCc1nc(-c2ccc(F)cc2)c(-c2ccnc(N(C(C)=O)C3CC3)c2)s1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20160102083A1,Cc1cc(C)c(CNC(=O)c2csc(N3CCCCC3C3CCN(C(=O)OC(C)(C)C)CC3)c2C)c(=O)[nH]1>>Cc1cc(C)c(CNC(=O)c2csc(N3CCCCC3C3CCNCC3)c2C)c(=O)[nH]1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100137286A1,COC(=O)[C@@H]1CC[C@@H](Oc2ccccc2C)CC1.NN>>Cc1ccccc1O[C@@H]1CC[C@@H](C(=O)NN)CC1,,Cc1ccccc1,,O,,test
US09376441B2,CC(=O)OC(C)=O.C[C@@H](Oc1cc(-c2ccc(N3CCNCC3)cn2)cc2ncn(C3CC3)c12)[C@H]1CNC(=O)C1>>CC(=O)N1CCN(c2ccc(-c3cc(O[C@H](C)[C@H]4CNC(=O)C4)c4c(c3)ncn4C3CC3)nc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110251178A1,COC(=O)c1cc(-c2ccc(F)cc2)n[nH]1.ClCCBr>>COC(=O)c1cc(-c2ccc(F)cc2)nn1CCCl,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040014962A1,CC(C)(C)[Si](OC1CN(c2nc(C(=O)N3CC(NC(=O)OCc4ccc([N+](=O)[O-])cc4)C3)cs2)C1)(c1ccccc1)c1ccccc1>>O=C(NC1CN(C(=O)c2csc(N3CC(O)C3)n2)C1)OCc1ccc([N+](=O)[O-])cc1,,C1CCOC1,,CC(=O)O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20140200227A1,Cc1ccc(S(=O)(=O)OC[C@@H](NC(=O)OC(C)(C)C)[C@H](O)[C@H](CN=[N+]=[N-])C2CC2)cc1>>CC(C)(C)OC(=O)N[C@@H]1CNC[C@H](C2CC2)[C@H]1O,[Pd],CO,,CCN(C(C)C)C(C)C,,test
US20140163008A1,CCOP(=O)(OCC)C(C)C#N.O=C1c2ccc(Br)cc2COc2cc(F)ccc21>>CC(C#N)=C1c2ccc(Br)cc2COc2cc(F)ccc21,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20150087585A1,CCOC(=O)[C@@H]1CCCN(c2ccc3nc(C4(n5cc(Cl)cn5)CC4)[nH]c3n2)C1>>O=C(O)[C@@H]1CCCN(c2ccc3nc(C4(n5cc(Cl)cn5)CC4)[nH]c3n2)C1,,C1CCOC1,O,[Li+].[OH-],,test
US06201156B1,CCOCc1ccccc1.O=C1c2ccccc2C(=O)N1O>>CCOC(=O)c1ccccc1.O=Cc1ccccc1,,CC#N,,,,test
US06372752B1,NCCc1ccc(Cl)cc1.O=C(O)Cc1ccccc1F>>O=C(Cc1ccccc1F)NCCc1ccc(Cl)cc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20130045949A1,CI.CN(C)Cc1ccccc1[N+](=O)[O-]>>C[N+](C)(C)Cc1ccccc1[N+](=O)[O-].[I-],,ClCCl,,,,test
US20090124569A1,COc1cccc(B(O)O)c1.O=c1c(Br)coc2ccccc12>>COc1cccc(-c2coc3ccccc3c2=O)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,O=C([O-])[O-].[K+].[K+],,test
US20080261969A1,CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CN(OC(C)(C)C)C1)C2c1ccc(Sc2nc3cc(Cl)ccc3[nH]2)o1.Cl>>CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CNC1)C2c1ccc(Sc2nc3cc(Cl)ccc3[nH]2)o1.Cl,,C1COCCO1,,,,test
US20160083362A1,COC(=O)Cl.COC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2Br)ccc2c1OC[C@@H]1C[C@H]21>>COC(=O)c1c(N(C(=O)OC)S(=O)(=O)c2ccc(F)cc2Br)ccc2c1OC[C@@H]1C[C@H]21,,C1CCOC1,O,[H-].[Na+],,test
US20040014962A1,C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(SC3CN(c4nc(C(=O)N[C@@H]5CCN(C(=O)OCc6ccc([N+](=O)[O-])cc6)C5)cs4)C3)[C@H](C)[C@H]12>>C[C@@H](O)[C@H]1C(=O)N2C(C(=O)O)=C(SC3CN(c4nc(C(=O)N[C@@H]5CCNC5)cs4)C3)[C@H](C)[C@H]12,,C1CCOC1,,,,test
US04288449,COC(=O)C1C=C(n2cccc2)C(Sc2ccccc2)=C([N+](=O)[O-])C1=S(=O)=O>>COC(=O)C1C=C(n2cccc2)C(Sc2ccccc2)=C(N)C1=S(=O)=O,[Pd],CCOC(C)=O,,C,,test
US05272163,CC(O)(C(=O)O)C(F)(F)F.Cc1cc(N)ccc1S(=O)(=O)c1ccccc1>>Cc1cc(NC(=O)C(C)(O)C(F)(F)F)ccc1S(=O)(=O)c1ccccc1,,CC(=O)N(C)C,,O,O=S(Cl)Cl,test
US20070010637A1,CC1=C(c2cc(C)ccc2N)C(=O)CC1.Cc1ccc(S(=O)(=O)Cl)cc1>>CC1=C(c2cc(C)ccc2NS(=O)(=O)c2ccc(C)cc2)C(=O)CC1,,c1ccncc1,,,,test
US20040077867A1,COC(=O)C(=Cc1ccc(OC)cc1[N+](=O)[O-])C(=O)OC>>COC(=O)C(Cc1ccc(OC)cc1[N+](=O)[O-])C(=O)OC,,CO,,Cl,[BH4-].[Na+],test
US20080021059A1,CCN.CN(c1cc(-c2cccnc2)cc2nc(N)nn12)C1CCCCC1.Cc1ccc(S(=O)(=O)N=C=O)cc1>>CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(N(C)C3CCCCC3)n2n1,,C1CCOC1,CN(C)C=O,,,test
US20150210682A1,BrBr.COC(=O)Cc1cccc(O)c1>>COC(=O)Cc1cc(O)ccc1Br,,CC(=O)O,,,,test
US05498755,CC(C)I.CC1(C)CC(=O)Nc2ccccc21>>CC(C)N1C(=O)CC(C)(C)c2ccccc21,,CN(C)C=O,,[H-].[Na+],,test
US20020111492A1,BrCCBr.Oc1ccc(F)c(F)c1>>Fc1ccc(OCCBr)cc1F,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070208014A1,C/C=C/Br.O=C(c1nc2cc(Cl)c(Cl)cc2[nH]1)C(F)(F)F>>C/C=C/C(O)(c1nc2cc(Cl)c(Cl)cc2[nH]1)C(F)(F)F,,C1CCOC1,ClCCl,II,[Mg],test
US20110190330A1,CC(C)N.COc1ccc(F)c(-c2ccc(COC(=O)C(C)(C)C)cc2C(=O)O)c1>>COc1ccc(F)c(-c2ccc(COC(=O)C(C)(C)C)cc2C(=O)NC(C)C)c1,CN(C)C=O,ClCCl,,O=S(Cl)Cl,,test
US20160120841A1,COc1ccc2c(c1)OC(c1cccnc1)CC2=NO>>COc1ccc2c(c1)OC(c1cccnc1)CC2N,[Ni],CO,N,[H][H],,test
US04898864,CC1(C)CCC(C)(C)c2cc(C(=O)C3CCCCC3C(=O)O)ccc21>>CC1(C)CCC(C)(C)c2cc(C(O)C3CCCCC3C(=O)O)ccc21,[Zn],CC(=O)O,,Cl,,test
US20080318998A1,CC(C)(C)OC(=O)NCCCI.CCCc1nc2cnc3cc(O)ccc3c2s1>>CCCc1nc2cnc3cc(OCCCNC(=O)OC(C)(C)C)ccc3c2s1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04230707,COC(=O)c1ccc(Cl)nc1.COC(=O)c1sc(C)cc1N>>COC(=O)c1ccc2nc3cc(C)sc3c(=O)n2c1,,CO,,,,test
US04820726,COc1c(C(C)=O)ccc(OCCCOc2cccc([N+](=O)[O-])c2)c1CCC(F)(F)F>>COc1c(C(C)=O)ccc(OCCCOc2cccc(N)c2)c1CCC(F)(F)F,[Ni],C1CCOC1,,,,test
US20040034218A1,Nc1ccc(C(=O)c2ccc(Cl)cc2)cc1C(SCC(=O)O)c1cccc(Cl)c1>>O=C1CSC(c2cccc(Cl)c2)c2cc(C(=O)c3ccc(Cl)cc3)ccc2N1,,Cc1ccccc1,,O=S(=O)([O-])[O-].[Mg+2],,test
US20120059002A1,COc1ccc2c(=O)[nH]c(-c3cc(C)c(OCCO[Si](C)(C)C(C)(C)C)c(C)c3)nc2c1>>COc1ccc2c(=O)[nH]c(-c3cc(C)c(OCCO)c(C)c3)nc2c1,,O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120238574A1,O=[N+]([O-])c1ccc(C=C2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1>>Nc1ccc(CC2CCN(Cc3ccc(C(O)(C(F)(F)F)C(F)(F)F)cc3)CC2)cc1,[Pd],CCOC(C)=O,,[H][H],,test
US20130085154A1,CC(=O)Oc1cc2c(s1)CCN(C(C(=O)C1CC1)c1ccccc1F)C2.O=P(O)(O)O>>CC(=O)Oc1cc2c(s1)CCN(C(C(=O)C1CC1)c1ccccc1F)C2.O=P([O-])([O-])[O-],,ClCCl,,,,test
US20090099169A1,BrP(Br)Br.CCCc1cc2cc(Cl)cc(CO)c2o1>>CCCc1cc2cc(Cl)cc(CBr)c2o1,,ClCCl,,,,test
US04652651,CC(C)=C(O)[C@H](O)C=O.COc1ccc(CN)c(OC)c1>>COc1ccc(CN=C[C@@H](O)C(O)=C(C)C)c(OC)c1,,ClCCl,,O=S(=O)([O-])[O-].[Mg+2],,test
US20130190332A1,COc1cc(-c2cnn(C(=O)OC(C)(C)C)c2)cn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc12>>COc1cc(-c2cn[nH]c2)cn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc12,,CO,ClCCl,Cl,[Na+].[OH-],test
US20040157891A1,COc1ccc(-c2nc(CSc3ccccn3)oc2-c2ccc(OCCNS(C)(=O)=O)cc2)cn1.CS(=O)(=O)O>>COc1ccc(-c2nc(CSc3ccccn3)oc2-c2ccc(OCCNS(C)(=O)=O)cc2)cn1.CS(=O)(=O)O,,CCOC(C)=O,,,,test
US20060252768A1,O.O=C(CBr)c1ccc(Cl)cc1>>O=CC(=O)c1ccc(Cl)cc1,,O,,CS(C)=O,,test
US20080261967A1,CCOC(=O)C=Cc1cc(F)ccc1OC>>CCOC(=O)CCc1cc(F)ccc1OC,[Pd],CCO,,,,test
US20080027036A1,CCC(O)(c1ccccc1)c1ccc2occc2c1>>CCC(c1ccccc1)c1ccc2occc2c1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20050233988A1,Brc1cc(Br)c2c(c1)CCO2>>Brc1ccc2c(c1)CCO2,,CCOCC,,[Li]CCCC,[Cl-].[NH4+],test
US05264415,CI.O=C1Oc2ccccc2C1(Cc1ccccc1)Cn1cncn1.[OH-]>>COc1ccccc1C(Cc1ccccc1)(Cn1cncn1)C(=O)O,,CO,O,Cl,,test
USRE028939,CCN(CC)C(=N)c1cc(C(F)(F)F)ccc1Br.NN>>CCN(CC)c1n[nH]c2ccc(C(F)(F)F)cc12,,CCCCO,,,,test
US20140142097A1,Nc1ccncc1.Nc1ncc(Br)cc1C(=O)O>>Nc1ncc(Br)cc1C(=O)Nc1ccncc1,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100152163A1,CN1CCc2[nH]c3ccc(Cl)cc3c2CC1.O=C(CCl)N1CCCCC1>>CN1CCc2c(n(CC(=O)N3CCCCC3)c3ccc(Cl)cc23)CC1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20120077796A1,CCOC(C)=O.COc1cc(C(C#N)Cc2ccccc2)ccc1F>>CCOC(=O)C(C#N)(Cc1ccccc1)c1ccc(F)c(OC)c1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20070078120A1,CI.COc1cccc(C2(CO)CCN(c3ccccc3OC)CC2)c1>>COCC1(c2cccc(OC)c2)CCN(c2ccccc2OC)CC1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US05210092,CC(=O)O.COC1CCC(OC)O1.Cc1ccc(N)c(Br)c1>>Cc1ccc(-n2cccc2)c(Br)c1,,CC(=O)O,,,,test
US20140107194A1,CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O.CCCOC(=O)c1ccc(C[C@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@@H]2O)cc1>>CCCOC(=O)c1ccc(C[C@]2(C3=Cc4ccccc4C3)Cc3ccccc3[C@@H]2OC(=O)[C@@H](N)CC(C)C)cc1,CN(C)c1ccncc1,CCOC(C)=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20030125370A1,C1CN[C@H](CNC2CC2)C1.Cc1[nH]c(C=O)c(C)c1C(=O)O>>Cc1[nH]c(C=O)c(C)c1C(=O)N1CCC[C@H]1CNC1CC1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20120184542A1,C[C@@H](N)c1ccccc1.Nc1cc(C(=O)On2nnc3ccccc32)ccc1Cl>>C[C@@H](NC(=O)c1ccc(Cl)c(N)c1)c1ccccc1,,ClCCl,,CCN(CC)CC,CN(C)C=O,test
US05128448,C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1CCCCC1>>C[C@H](NC1CCCCC1)C(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20030232889A1,CC1(C)OCC(O)CO1.O=C1c2ccccc2C(=O)N1O>>CC1(C)OCC(ON2C(=O)c3ccccc3C2=O)CO1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040142980A1,O.O=C1OC(c2ccco2)=N/C1=C\c1ccc(-c2ccccc2)o1>>O=C(O)/C(=C/c1ccc(-c2ccccc2)o1)NC(=O)c1ccco1,,CC(C)=O,,CO,[Na+].[OH-],test
US20080269208A1,CCOC(=O)C1(C(=O)OCC)CCCN1C(=O)CBr.NCc1ccccc1>>CCOC(=O)C12CCCN1C(=O)CN(Cc1ccccc1)C2=O,,CC#N,,,,test
US20060004108A1,CC1(C)C2CC[C@@]1(C)C(=O)CC2=O.O=C=Nc1ccc(C(F)(F)F)cc1>>CC1(C)C2CC[C@@]1(C)C(=O)C(C(=O)Nc1ccc(C(F)(F)F)cc1)C2=O,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20160016910A1,CC(C)(C)[S@@](N)=O.O=Cc1c(F)cccc1F>>CC(C)(C)[S@](=O)N=Cc1c(F)cccc1F,,ClCCl,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100160323A1,CCOC(=O)C(=O)N1CCN(C(=O)c2cc(F)ccc2C(F)(F)F)CC1>>O=C(O)C(=O)N1CCN(C(=O)c2cc(F)ccc2C(F)(F)F)CC1,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20060147747A1,CC(=O)Nc1cc(Br)ccc1Nc1ccccc1>>Cc1nc2cc(Br)ccc2n1-c1ccccc1,,Cc1ccccc1C,,,,test
US05017576,COc1cccc2c1C(=O)CC(c1ccc(C)cc1)=N2.O=C(CCl)N1CCOCC1>>COc1cccc2nc(-c3ccc(C)cc3)cc(OCC(=O)N3CCOCC3)c12,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100261677A1,NCc1ccccc1.O=C(O)c1cccc2cc(NS(=O)(=O)c3cc(Cl)cc(Cl)c3)ccc12>>O=C(NCc1ccccc1)c1cccc2cc(NS(=O)(=O)c3cc(Cl)cc(Cl)c3)ccc12,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US04077795,CC(C)(C)c1cc([N+](=O)[O-])c(Cl)c([N+](=O)[O-])c1.CNC>>CN(C)c1c([N+](=O)[O-])cc(C(C)(C)C)cc1[N+](=O)[O-],,O,,CCO,,test
US04066772,O=S(Cl)Cl.OCCCCn1cnc2ccccc21>>ClCCCCn1cnc2ccccc21,,ClC(Cl)Cl,,,,test
US20120208844A1,CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCC(O)(c2ccccc2OCCCC(=O)OCC)CC1>>CCC[C@H]1N(C(=O)c2cnccc2C(F)(F)F)CCC[C@@]1(Oc1csc(C(F)(F)F)c1)C(=O)N1CCC(O)(c2ccccc2OCCCC(=O)O)CC1,,CCOC(C)=O,CO,[K+].[OH-],,test
US05319096,Cc1cn(N2C(=O)c3ccccc3C2=O)c2ccccc12.O=C(Cl)c1ccc(F)cc1>>Cc1c(C(=O)c2ccc(F)cc2)n(N2C(=O)c3ccccc3C2=O)c2ccccc12,,ClCCl,,Cl[Sn](Cl)(Cl)Cl,,test
US20040176421A1,COC(=O)C1NCC(NC(=O)OCC#CCOC(=O)NC2CNC(C(=O)OC)C2C(=O)CCc2ccc(CNC(=O)OC(C)(C)C)cc2)C1C(=O)CCc1ccc(CNC(=O)OC(C)(C)C)cc1>>CC(C)(C)OC(=O)NCc1ccc(CCC(=O)C2C(NC(=O)OCC#CCOC(=O)NC3CNC(C(=O)O)C3C(=O)CCc3ccc(CNC(=O)OC(C)(C)C)cc3)CNC2C(=O)O)cc1,,CCO,,[Na+].[OH-],,test
US20120316161A1,CC(C)c1nc(N)n[nH]1.COC(=O)CC(C(C)=O)C(=O)OC>>COC(=O)Cc1c(C)nc2nc(C(C)C)nn2c1O,,Cc1ccccc1,,,,test
US20160122344A1,CCOC(=O)c1cn2c(cc1=O)-c1cc(Cl)c(OCCCOC)cc1CC2C1CCOCC1>>COCCCOc1cc2c(cc1Cl)-c1cc(=O)c(C(=O)O)cn1C(C1CCOCC1)C2,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20140275026A1,COc1nccc2c(-c3cc([N+](=O)[O-])ccc3Oc3ccc(F)cc3F)cn(C)c12>>COc1nccc2c(-c3cc(N)ccc3Oc3ccc(F)cc3F)cn(C)c12,[Pd],CCOC(C)=O,,[H][H],,test
US20080090839A1,CC(C)(C)OC(=O)N1CCCC1COc1ccc(OCc2ccccc2)cc1>>CC(C)(C)OC(=O)N1CCCC1COc1ccc(O)cc1,[Pd],C1CCOC1,,CCO,,test
US20110195954A1,COc1ccc2c(c1)CCN(C1CCNCC1)C(=O)N2.N#Cc1cnc(Cl)cc1Cl>>COc1ccc2c(c1)CCN(C1CCN(c3cc(Cl)c(C#N)cn3)CC1)C(=O)N2,CN(C)c1ccncc1,CCO,,CCN(C(C)C)C(C)C,,test
US20150225342A1,C1=CCC2CNCC2C1.O=C(Cl)OCc1ccccc1>>O=C(OCc1ccccc1)N1CC2CC=CCC2C1,,ClCCl,,CCN(CC)CC,O,test
US20140094465A1,COc1ccc2c(=O)oc(C)cc2c1.N[C@@H]1CC[C@@H](C(=O)O)CC1>>COc1ccc2c(=O)n([C@@H]3CC[C@@H](C(=O)O)CC3)c(C)cc2c1,,CN(C)C=O,,,,test
US20090118261A1,Cc1ccc(NC(=O)c2cncc(C#CCN(C)C)c2)cc1Nc1ccc2ncn(C)c(=O)c2c1>>Cc1ccc(NC(=O)c2cncc(CCCN(C)C)c2)cc1Nc1ccc2ncn(C)c(=O)c2c1,[Pd],CO,,,,test
US20040132994A1,CC(C)(C)OC(=O)N[C@H]1CCNC1.Cn1ncc(NC(=O)Oc2ccccc2)c1NC(c1ccccc1)(c1ccccc1)c1ccccc1>>Cn1ncc(NC(=O)N2CC[C@H](NC(=O)OC(C)(C)C)C2)c1NC(c1ccccc1)(c1ccccc1)c1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05449785,CI.CO[C@@H]1OC[C@@H](OCc2ccccc2)[C@H](O)[C@H]1OCc1ccccc1>>CO[C@@H]1[C@@H](OCc2ccccc2)[C@H](OC)OC[C@H]1OCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20090325947A1,COCCCN1CCOc2ccc(CO[C@H]3CN(C(=O)OC(C)(C)C)[C@@H](CC(C)(C)C(=O)OC)C[C@@H]3c3ccc(COCCOC)cc3)cc21>>COCCCN1CCOc2ccc(CO[C@H]3CN(C(=O)OC(C)(C)C)[C@@H](CC(C)(C)C(=O)O)C[C@@H]3c3ccc(COCCOC)cc3)cc21,,C1CCOC1,CCO,[Na+].[OH-],,test
US20060122065A1,COc1ccc(CCC(=O)Cl)cc1OC.COc1ccc(CN)cc1C>>COc1ccc(CNC(=O)CCc2ccc(OC)c(OC)c2)cc1C,,CCN(CC)CC,,Cl,,test
US20070249670A1,CC(C)(C)OC(=O)c1cc(Br)sc1N.O=C=Nc1c(Cl)cccc1Cl>>CC(C)(C)OC(=O)c1cc(Br)sc1NC(=O)Nc1c(Cl)cccc1Cl,,CN(C)C=O,,CCN(CC)CC,,test
US05155122,CC(C)(C)c1cc(C(=O)NNC(N)=S)c(O)c(C(C)(C)C)c1>>CC(C)(C)c1cc(-c2n[nH]c(=S)[nH]2)cc(C(C)(C)C)c1O,,CO,,C[O-].[Na+],,test
US20100267699A1,CC(=O)CCl.Oc1ccc(C2CCN(C3=Nn4c(nnc4C(F)(F)F)CC3)CC2)cc1>>CC(=O)COc1ccc(C2CCN(C3=Nn4c(nnc4C(F)(F)F)CC3)CC2)cc1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20110034440A1,CCCCC([Sn])=C(CCCC)CCCC.CN(C)C=O.N#Cc1ccc(Cl)c([N+](=O)[O-])c1>>C=Cc1ccc(C#N)cc1[N+](=O)[O-],Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCCCCC,CCOC(C)=O,,,test
US20120101134A1,Cc1c(Br)cccc1C#N.NO>>Cc1c(Br)cccc1C(=N)NO,,CCO,,Cl,O=C([O-])O.[Na+],test
US20110152285A1,CCOC(=O)c1[nH]c(C)c(C(=O)OCC)c1-c1ccccc1.CSCCCl>>CCOC(=O)c1c(-c2ccccc2)c(C(=O)OCC)n(CCSC)c1C,,CS(C)=O,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US20060152146A1,Cc1ccc2cc(Br)ccc2c1.O=Cc1ccccc1B(O)O>>Cc1ccc2cc(-c3ccccc3C=O)ccc2c1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20160052888A1,CCOC/C=C\[C@@H]1CCc2cc([C@H]3CC[C@]4(COC(=O)N4)C3)ccc2C1>>CCOCCC[C@@H]1CCc2cc([C@H]3CC[C@]4(COC(=O)N4)C3)ccc2C1,O=[Pt]=O,C1CCOC1,,,,test
US20030069242A1,CCCSc1cc(-c2c[nH]nc2C(F)(F)F)ccc1C=O>>CCCSc1cc(-c2c[nH]nc2C(F)(F)F)ccc1C,,ClCCl,,CC[SiH](CC)CC,,test
US08835628B2,CCOC(=O)C(Br)CC.Nc1cccc(Br)c1O>>CCC1Oc2c(Br)cccc2NC1=O,,CN1CCCC1=O,,C1CCC2=NCCCN2CC1,,test
US04912104,CCCCn1c(=O)n(CCC)c(=O)c2c(N)n(CCCCl)nc21>>CCCCn1c(=O)n(CCC)c(=O)c2c3n(nc21)CCCN3,,CN(C)C=O,,[H-].[Na+],,test
US20020198129A1,CCCCCCCCCCCCCCCCCC(=O)OC.CN(C)CCCN>>CCCCCCCCCCCCCCCCCC(=O)NCCCN(C)C,,CO,,,,test
US20100093757A1,Cc1cnc(NC(=O)[C@H](COC2CCC2)Oc2ncnc3c2cnn3-c2ccccc2Cl)cn1>>Cc1cnc(NC(=O)[C@H](COC2CCC2)Oc2ncnc3c2cnn3-c2ccccc2)cn1,[Pd],CCO,,,,test
US05059589,CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O.CCN=C=NCCCN(C)C.CN1CCOCC1.On1nnc2ccccc21>>C=CC(O)[C@H](CC1CCCCC1)NC(=O)OC(C)(C)C,,Cl,,O=C([O-])O.[Na+],,test
US20100267712A1,CCOC(=O)c1cc(O)ccc1C.CI>>CCOC(=O)c1cc(OC)ccc1C,,CN(C)C=O,,O,[H-].[Na+],test
US20160251339A1,CCOC1(O[Si](C)(C)C)CC1.COc1ccc(S(=O)(=O)n2cc(C(F)F)c3ccc(C(F)(F)F)cc32)cc1N1CCNCC1>>COc1ccc(S(=O)(=O)n2cc(C(F)F)c3ccc(C(F)(F)F)cc32)cc1N1CCN(C2CC2)CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20090215778A1,COc1ccc(-c2nc3c(C(=O)O)cnn3c(C(F)(F)F)c2C)cc1.C[C@@H]1CN([C@@H](C)c2cc(F)cc(F)c2F)CCN1>>COc1ccc(-c2nc3c(C(=O)N4CCN([C@@H](C)c5cc(F)cc(F)c5F)C[C@H]4C)cnn3c(C(F)(F)F)c2C)cc1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130059834A1,CC1(C)OCC(COS(C)(=O)=O)O1.C[C@@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3n[nH]c4cc(Cl)ccc34)nc12)C(=O)N1CC(C#N)C1>>C[C@@H](NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(CC4COC(C)(C)O4)c4cc(Cl)ccc34)nc12)C(=O)N1CC(C#N)C1,,CN(C)C=O,,[H-].[Na+],,test
US20100197715A1,CN1CC(NC(=O)OC(C)(C)C)(c2ccccc2)CCC1(C)C>>CN1CC(N)(c2ccccc2)CCC1(C)C,,C1COCCO1,,CO,Cl,test
US20030065187A1,CCCCO.Ic1cccnc1>>CCCCOc1cccnc1,[Cu]I,CCCCO,,c1cnc2c(c1)ccc1cccnc12,O=C([O-])[O-].[Cs+].[Cs+],test
US20080051416A1,Cc1ccc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC(C)(C)C)cc1C(=O)O.Cc1ccc(CN)cc1>>Cc1ccc(CNC(=O)c2cc(C(=O)NCC(C)(C)C)ccc2-c2cc(C(=O)NC3CC3)ccc2C)cc1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110152281A1,CN1CCN(C(=S)NN)CC1.O=C(c1ccccc1)c1ccnnc1>>CN1CCN(C(=S)NN=C(c2ccccc2)c2ccnnc2)CC1,,CCO,ClCCl,,,test
US20160214940A1,C1COCCN1.CCOC(=O)c1cn(-c2ccc(F)cc2)c2ccc(Br)cc2c1=O.CCOC(=O)c1cn(-c2ccc(F)cc2)c2ccc(C=O)cc2c1=O.ClCCl>>CCOC(=O)c1cn(-c2ccc(F)cc2)c2ccc(C=O)cc2c1=O.CCOC(=O)c1cn(-c2ccc(F)cc2)c2ccc(CN3CCOCC3)cc2c1=O,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US06114532,CCOC(=O)Cn1c(Cc2ccc(C(=N)N)cc2)nc2cc(NS(=O)(=O)c3ccccc3)ccc21>>N=C(N)c1ccc(Cc2nc3cc(NS(=O)(=O)c4ccccc4)ccc3n2CC(=O)O)cc1,,CCO,,Cl,[Na+].[OH-],test
US20160115125A1,C[C@@H](N)CO.Cc1cc(NC(=O)c2cc(S(=O)(=O)Cl)cn2C)ccc1F>>Cc1cc(NC(=O)c2cc(S(=O)(=O)N[C@H](C)CO)cn2C)ccc1F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150232445A1,CI.COC(=O)N1c2ccc(-c3csc(C4(O)CN(C(=O)OC(C)(C)C)C4)n3)c(OC3CCC3)c2CC[C@@H]1C>>COC(=O)N1c2ccc(-c3csc(C4(OC)CN(C(=O)OC(C)(C)C)C4)n3)c(OC3CCC3)c2CC[C@@H]1C,,CN(C)C=O,,O,[H-].[Na+],test
US20160200725A1,CNC1CCN(C(=O)OC(C)(C)C)CC1.COC(=O)CBr>>COC(=O)CN(C)C1CCN(C(=O)OC(C)(C)C)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090018132A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(OCC1(c2ccc(F)cc2)CCNCC1)c1cc(C2CC2)cc2c[nH]nc12>>CC(OCC1(c2ccc(F)cc2)CCN(C(=O)OC(C)(C)C)CC1)c1cc(C2CC2)cc2cn[nH]c12,,ClCCl,,,,test
US05143912,COC1CN(C(=O)c2cc(-c3ccccc3)c(=O)[nH]c2-c2c(Cl)cccc2C#N)C1>>COC1CN(C(=O)c2cc(-c3ccccc3)c(=O)n3c2-c2c(Cl)cccc2C3)C1,[Zn],O,,CC(=O)O,,test
US20150210682A1,BrCCCn1cncn1.CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(O)cc1CC2C(C)(C)C>>CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCCCn3cncn3)cc1CC2C(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020040040A1,CC(=O)c1ccc(-c2cc(-c3ccccc3C)c(C(=O)N(C)Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)cn2)s1>>Cc1ccccc1-c1cc(-c2ccc(C(C)O)s2)ncc1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1,,CCO,,C1CCOC1,[BH4-].[Na+],test
US20070082933A1,CC(=O)OCCBr.COc1cc(C=O)ccc1O>>COc1cc(C=O)ccc1OCCOC(C)=O,,CC(C)=O,CCOCC,O=C([O-])[O-].[K+].[K+],,test
US20100189656A1,CC(=O)OCC(OC(C)=O)C(=O)Nc1c(I)c(C(=O)Cl)c(I)c(C(=O)Cl)c1I.CC1(C)OCC(CN)O1>>CC(=O)OCC(OC(C)=O)C(=O)Nc1c(I)c(C(=O)Cl)c(I)c(C(=O)NCC2COC(C)(C)O2)c1I,,CC(=O)N(C)C,,,,test
US20130317024A1,COC(=O)c1cc(Br)n(C(C)C)c1.O=Cc1ccc(Cl)cc1>>COC(=O)c1cc(Br)n(C(C)C)c1C(O)c1ccc(Cl)cc1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US04855324,CCCCCCCCC(O)/C=C/C=C/c1ccc(C(=O)CCCC(=O)OC)s1>>CCCCCCCCC(O)/C=C/C=C/c1ccc(C(O)CCCC(=O)OC)s1,,CO,,[BH4-].[Na+],,test
US20100280014A1,Cc1ccccc1N1CCN(C(=O)C(F)(F)F)CC1.O=S(=O)(O)Cl>>Cc1ccc(S(=O)(=O)Cl)cc1N1CCN(C(=O)C(F)(F)F)CC1,,ClCCl,,,,test
US06476077B1,COc1c(C#N)cc2ccccc2c1C(=O)N(C)C[C@@H](CCO)c1ccc(Cl)c(Cl)c1>>COc1c(C#N)cc2ccccc2c1C(=O)N(C)C[C@@H](CC=O)c1ccc(Cl)c(Cl)c1,,CS(C)=O,,O=C(Cl)C(=O)Cl,,test
US20160060282A1,COc1ccccc1CC(C)=O.C[C@@H](N)c1ccccc1>>COc1ccc(C[C@@H](C)N[C@H](C)c2ccccc2)cc1,,CO,,O=CO,,test
US20070135454A1,N#CCc1ccc(C(F)(F)F)cc1F>>NCCc1ccc(C(F)(F)F)cc1F,,C1CCOC1,,,,test
US20040048908A1,COC(=O)CCc1cnoc1-c1ccc(OC)cc1>>COc1ccc(-c2oncc2CCCO)cc1,,C1CCOC1,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20120015966A1,COC(=O)CCc1cn(S(=O)(=O)c2cncc(Br)c2)c2ccc(Cl)cc12.OB(O)c1ccc(C(F)(F)F)cc1>>O=C(O)CCc1cn(S(=O)(=O)c2cncc(-c3ccc(C(F)(F)F)cc3)c2)c2ccc(Cl)cc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US04436748,CCOC(=O)CBr.CCc1cc2cc(O)c(Cl)c(Cl)c2s1>>CCOC(=O)COc1cc2cc(CC)sc2c(Cl)c1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110021625A1,CC(C)[Si](OS(=O)(=O)C(F)(F)F)(C(C)C)C(C)C.COc1cc2c(cc1O)C(C#N)(CCCOC1CCCCO1)C2>>COc1cc2c(cc1O[Si](C(C)C)(C(C)C)C(C)C)C(C#N)(CCCOC1CCCCO1)C2,,ClCCl,,CCN(CC)CC,,test
US20040063175A1,CC(=O)C(=O)[O-].Cc1ncc(COP(=O)(O)O)c(C=O)c1O.N[C@@H](CCC(=O)[O-])C(=O)[O-]>>N[C@@H](C[C@@](O)(Cc1c[nH]c2ccccc12)C(=O)O)C(=O)O,,O,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140066425A1,C=CC#N.COC(=O)C(C(=O)OC)c1ccc([N+](=O)[O-])cc1F>>COC(=O)C(CCC#N)c1ccc([N+](=O)[O-])cc1F,,CO,,CO[Na],,test
US05834257,OC[C@H]1O[C@@H](O[C@H]2[C@H]3OC[C@@H]2O[C@@H](O[C@@H]2[C@@H](O)C(O)O[C@H](CO)[C@@H]2O)[C@@H]3O)[C@H](O)[C@@H](O[C@@H]2O[C@H]3CO[C@@H]([C@H]2O)[C@@H]3O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@H]3O[C@H]4CO[C@H]([C@@H]4O)[C@H]3O)[C@H]2O)[C@H]1O>>OC[C@H]1O[C@@H](O[C@@H]2[C@@H]3CO[C@H]2[C@H](O)[C@H](O[C@@H]2[C@@H](O)[C@H](O)O[C@H](CO)[C@@H]2O)O3)[C@H](O)[C@@H](O[C@@H]2O[C@H]3CO[C@@H]([C@@H]2O)[C@@H]3O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H]1O,,O=P([O-])([O-])[O-],,,,test
US04416884,CC1CCc2c(Cl)c(Cl)cc3c(=O)c(C(=O)O)cn1c23.O=C(N1CCNCC1)C(F)(F)F>>CC1CCc2c(N3CCN(C(=O)C(F)(F)F)CC3)c(Cl)cc3c(=O)c(C(=O)O)cn1c23,,CN(C)P(=O)(N(C)C)N(C)C,,,,test
US20110077252A1,N#Cc1ccc(N)cn1.O=C(OC(=O)C(F)(F)Cl)C(F)(F)Cl>>N#Cc1ccc(NC(=O)C(F)(F)Cl)cn1,,CN(C)C=O,O,[H-].[Na+],,test
US20070099986A1,NCCc1ccccc1OC(F)(F)F.NS(=O)(=O)c1cc(C(=O)CCCCCl)cc2c1OCC2>>NS(=O)(=O)c1cc(C2=CCCCN2CCc2ccccc2OC(F)(F)F)cc2c1OCC2,,Cc1ccccc1,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20090264650A1,C1CCNCC1.O=C(c1ccc(CCl)cc1)C1CCN(C2CCCCC2)C1=O>>O=C(c1ccc(CN2CCCCC2)cc1)C1CCN(C2CCCCC2)C1=O,,CCOC(C)=O,,[I-].[K+],,test
US20130123268A1,CC(C)(C)OC(=O)N1C2CCC1CC(O)(c1cscn1)C2.Cl>>Cl.OC1(c2cscn2)CC2CCC(C1)N2,,C1COCCO1,,,,test
US20160002248A1,C#C[Mg]Cl.C[Si](C)(C)Cl.O=C1COC1>>C#CC1(O[Si](C)(C)C)COC1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20100113782A1,CCOC(=O)c1ccc(Cl)nc1.O=C(Nc1ccc2c(c1)CCC2)c1ccc(N2CCNCC2)cc1>>CCOC(=O)c1ccc(N2CCN(c3ccc(C(=O)Nc4ccc5c(c4)CCC5)cc3)CC2)nc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20120015962A1,Cn1cnc2c(NC(=O)c3csc4cnc(Cl)nc34)cccc21.N[C@H]1CCCC[C@H]1N>>Cn1cnc2c(NC(=O)c3csc4cnc(N[C@@H]5CCCC[C@@H]5N)nc34)cccc21,,C1COCCO1,,ClCCl,O,test
US20160016908A1,COc1ccc2c(c1)N(C(C)=O)[C@@H](C1CC1)[C@H](C)[C@H]2NC(=O)OCc1ccccc1>>COc1ccc2c(c1)N(C(C)=O)[C@@H](C1CC1)[C@H](C)[C@H]2N,[Pd],CCO,,[H][H],,test
US20030114469A1,CC(C)Cn1c(N)c(N)c(=O)n(C)c1=O.COc1ccc2cncc(CC(=O)O)c2c1>>COc1ccc2cncc(Cc3nc4c([nH]3)c(=O)n(C)c(=O)n4CC(C)C)c2c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20070049618A1,ClCCN1CCOCC1.O=[N+]([O-])c1ccc(O)cc1F>>O=[N+]([O-])c1ccc(OCCN2CCOCC2)cc1F,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US03953499,CCCCCC(C)=CCC=CCC=CCCCCCC(C)C(=O)O>>CCCCCC(C)=CCC=CCC=CCCCCCCC(=O)O,,O,,CCO,[K+].[OH-],test
US20140200197A1,CC(C)(C)OC(=O)N1C[C@@H](CCc2c(F)cncc2NC(=O)[C@@H](N)[C@@H](c2ccc(F)cc2)c2cc(F)cc(F)c2)OC[C@@H]1COC(=O)NCC(F)(F)F.COC(=O)Cl>>COC(=O)N[C@H](C(=O)Nc1cncc(F)c1CC[C@@H]1CN(C(=O)OC(C)(C)C)[C@@H](COC(=O)NCC(F)(F)F)CO1)[C@@H](c1ccc(F)cc1)c1cc(F)cc(F)c1,,ClCCl,,CCN(CC)CC,,test
US20040192653A1,BrC(Br)(Br)Br.CC(C)(C)OC(=O)N1CCOC(CO)C1>>CC(C)(C)OC(=O)N1CCOC(CBr)C1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US03975384,CSc1nc(N)c([N+](=O)[O-])c(Cl)n1.O=S1CCNCC1>>CSc1nc(N)c([N+](=O)[O-])c(N2CCS(=O)CC2)n1,,CC(C)=O,,,,test
US04500656,NC(=O)O.OCCNCCO>>O=C=O.OCCNCCO,,c1ccccc1,,,,test
US20110245257A1,CC(NC(=O)OCc1ccccc1)c1nc2cnccn2c1-c1ccccn1>>CC(N)c1nc2cnccn2c1-c1ccccn1,,O=C(O)C(F)(F)F,,CSC,,test
US06218376B1,COC(=O)c1nc(Cl)sc1CCc1cccc(Cl)c1>>O=C(O)c1nc(Cl)sc1CCc1cccc(Cl)c1,,C1CCOC1,O,[Na+].[OH-],,test
US20100010035A1,CCOC(=O)C(C)=C(C)N.COC(=O)CC(C)=O>>CCOC(=O)c1c(C)[nH]c(C)cc1=O,,CCOC(C)=O,,Cc1ccccc1C,,test
US05990116,CCc1ncnc2ccc(C#Cc3cc(OC)ccc3OC)cc12>>CCc1ncnc2ccc(CCc3cc(OC)ccc3OC)cc12,[Pd],CCOC(C)=O,,,,test
US20090298878A1,C1CCOC1.CCOC(=O)N=NC(=O)OCC.O=C1c2ccccc2C(=O)N1O.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>O=C1c2ccccc2C(=O)N1OCc1ccccn1,,C1CCOC1,,,,test
US20110021482A1,Cc1ccc(S(=O)(=O)ON=C(c2ccc(CO[Si](C)(C)C(C)(C)C)cc2)C(F)(F)F)cc1.N>>CC(C)(C)[Si](C)(C)OCc1ccc(C2(C(F)(F)F)NN2)cc1,,CCOCC,,,,test
US20100305096A1,Cn1c(CN2CCC(C(C)(C)O)CC2)nc2c(N3CCOCC3)nc(Cl)nc21.Ic1n[nH]c2ccccc12>>Cn1c(CN2CCC(C(C)(C)O)CC2)nc2c(N3CCOCC3)nc(-n3nc(I)c4ccccc43)nc21,,CN(C)C=O,,[H-].[Na+],,test
US20030134808A1,CO[C@H]1O[C@@](COCc2ccccc2)(COS(C)(=O)=O)[C@@H](OCc2ccccc2)[C@H]1O>>CO[C@@H]1O[C@@]2(COCc3ccccc3)CO[C@@H]1[C@@H]2OCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20140275175A1,Brc1cncc(Br)c1.CN1C(=O)Cc2c1ccc(B1OC(C)(C)C(C)(C)O1)c2C1CC1>>CN1C(=O)Cc2c1ccc(-c1cncc(Br)c1)c2C1CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,ClCCl,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20090270412A1,CCOC(=O)Cn1c2c(c3cc(C)ccc31)CCN(C)C2>>Cc1ccc2c(c1)c1c(n2CC(=O)O)CN(C)CC1,,C1CCOC1,O,[Na+].[OH-],,test
US20100240702A1,CCI.Cc1cccc2[nH]cc(C=O)c12>>CCn1cc(C=O)c2c(C)cccc21,,CN(C)C=O,ClCCl,[H-].[Na+],,test
US20070244117A1,O=C(O)c1ccccc1NCc1ccncc1.Oc1c(F)c(F)c(F)c(F)c1F>>O=C(Oc1c(F)c(F)c(F)c(F)c1F)c1ccccc1NCc1ccncc1,,CCOC(C)=O,,,,test
US20060223849A1,Cc1nc(C(=O)O)cc2ccccc12.Nc1nc2cccc(C(=O)Nc3ncc[nH]3)c2[nH]1>>Cc1nc(C(=O)Nc2nc3c(C(=O)Nc4ncc[nH]4)cccc3[nH]2)cc2ccccc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070078164A1,CCOC(=O)c1cccc(-c2cccc([C@H]3CCN(C(=O)OC(C)(C)C)C[C@@H]3OCc3ccc4ccccc4c3)c2)c1>>CC(C)(C)OC(=O)N1CC[C@H](c2cccc(-c3cccc(C(=O)O)c3)c2)[C@@H](OCc2ccc3ccccc3c2)C1,,C1CCOC1,CO,[Na+].[OH-],,test
US20050176742A1,CCOC(=O)c1c(NC(C)=O)sc2c(O)cc(Cc3ccccc3)cc12>>CCOC(=O)c1c(N)sc2c(O)cc(Cc3ccccc3)cc12,,CO,,O=S(=O)(O)O,,test
US20130253029A1,CC(C)(C)OC(=O)N1CC2C(C1)C2C(=NOc1ccccc1)c1ccc(Cl)c(Cl)c1.Cl>>Cl.Clc1ccc(C(=NOc2ccccc2)C2C3CNCC32)cc1Cl,,ClCCl,,,,test
US20150307445A1,COc1ccc2c(c1)CCCC2=O.O=CC(=O)O>>COc1ccc2c(c1)CCC(=CC(=O)O)C2=O,,COCCOCCOC,,O,O=S(=O)(O)O,test
US20160122364A1,Brc1cnc2c(N3CCOCC3)snc2c1.CCOC(=O)c1cccc(B(O)O)c1>>COC(=O)c1ccc(-c2cnc3c(N4CCOCC4)snc3c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20090163469A1,CI.Cc1nc(N=CN(C)C)sc1C(=O)C=CN(C)C.NC(N)=S>>CSc1nccc(-c2sc(N)nc2C)n1,,CCO,O,[Na+].[OH-],,test
US20120040985A1,CC(C)(C)[Si](C)(C)OCCCOc1cc(F)c(COS(C)(=O)=O)c(Cl)c1.COc1cc(C(C)(C)c2cnc(S)n2-c2ccc(F)cc2)ccc1F>>COc1cc(C(C)(C)c2cnc(SCc3c(F)cc(OCCCO[Si](C)(C)C(C)(C)C)cc3Cl)n2-c2ccc(F)cc2)ccc1F,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160237081A1,CCOP(=O)(CC(=O)N(C)OC)OCC.COc1c(F)ccc(F)c1C=O>>COc1c(F)ccc(F)c1/C=C/C(=O)N(C)OC,,CCOCC,,[H-].[Na+],,test
US20060166985A1,CC(C)(C)[Si](C)(C)OCC1OCc2cc(Cl)ccc21>>OCC1OCc2cc(Cl)ccc21,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110021537A1,CC(C)(C)OC(=O)CC[C@H](NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1)C(=O)O.CCCCOC(=O)NC1CCNC1>>CCCCOC(=O)NC1CCN(C(=O)[C@H](CCC(=O)O)NC(=O)c2cc(OCC(=O)N3CCC[C@H]3C(=O)NC3CCC3)n(-c3ccccc3)n2)C1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20120329785A1,CC(=O)c1ccc(N)cc1.COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1>>COc1ccc2nc(Nc3ccc(C(C)=O)cc3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US20120302540A1,CC(C)(C)OC(=O)N1CCCC(Nc2ccccc2)(C(N)=O)C1.CCOC(OCC)OCC>>CC(C)(C)OC(=O)N1CCCC2(C1)C(=O)N=CN2c1ccccc1,,Cc1ccccc1,,CC(=O)O,,test
US20070213336A1,CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2O)c1.Fc1cccc(CBr)c1>>CCCCCCCNC(=O)N(C)c1cccc(-c2ccc(CCC(=O)OC)cc2OCc2cccc(F)c2)c1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150266916A1,CCOc1ccc(Cc2cc([C@]34OC[C@@](C(O)C#C[Si](C)(C)C)(O3)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]4OCc3ccccc3)ccc2Cl)cc1>>CCOc1ccc(Cc2cc([C@]34OC[C@@](C(O)C#C[Si](C)(C)C)(O3)[C@@H](O)[C@H](O)[C@H]4O)ccc2Cl)cc1,,ClCCl,,ClB(Cl)Cl,,test
US05457201,COc1ccc(CCl)cc1.O=c1nc(C2CC2)c2cc(Cl)ccc2[nH]1>>COc1ccc(Cn2c(=O)nc(C3CC3)c3cc(Cl)ccc32)cc1,,CCCCCC,CN(C)C=O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05364871,COCc1sc(=N)[nH]c1-c1csc(N=C(N)N)n1.NS(N)(=O)=O>>NC(N)=Nc1nc(-c2nc(N)sc2C=NS(N)(=O)=O)cs1,,COCCO,,,,test
US20100029611A1,C[Sn](C)(C)c1ccc2nc(-c3ccc(C4OCCCO4)cc3F)sc2n1.O=C(O)C1CC(F)(F)C1>>O=C(c1ccc2nc(-c3ccc(C4OCCCO4)cc3F)sc2n1)C1CC(F)(F)C1,,Cc1ccccc1,,O=S(Cl)Cl,,test
US20060235222A1,CCC(O)(CC)c1ccc2sc(Cl)nc2c1.CS(=O)(=O)Nc1cccc2cc[nH]c12>>CCC(CC)(c1ccc2sc(Cl)nc2c1)c1c[nH]c2c(NS(C)(=O)=O)cccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100144745A1,C[Si](C)(C)CCOCn1ccc2nc(NC(=O)NC3CCCCC3)cnc21.O=C1CCC(=O)N1I>>C[Si](C)(C)CCOCn1cc(I)c2nc(NC(=O)NC3CCCCC3)cnc21,,CC(C)=O,,,,test
US05530017,CCCCc1ncc(CCC(=O)OCC)n1Cc1ccccc1Cl>>CCCCc1ncc(CCC(=O)O)n1Cc1ccccc1Cl,,CCO,O,Cl,[Na+].[OH-],test
US04788207,NC(=S)c1ccc(C(F)(F)F)cc1.O=CCBr>>FC(F)(F)c1ccc(-c2nccs2)cc1,,CCO,,Cl,,test
US20030199440A1,CCOC(=O)C1(NC(=O)c2ccc3c(Cl)cnc(NC(=N)N)c3c2)CCCC1>>N=C(N)Nc1ncc(Cl)c2ccc(C(=O)NC3(C(=O)O)CCCC3)cc12,,C1COCCO1,,Cl,[Na+].[OH-],test
US20130324506A1,CN1CCC(OC2c3ccccc3CCn3c2nc(-c2ccccc2)c3C(N)=O)CC1.[OH-]>>CN1CCC(OC2c3ccccc3CCn3c2nc(-c2ccccc2)c3C(=O)O)CC1,,O,,Cl,,test
US05238908,CC(C)CI.O=C1COc2cc(F)ccc2N1>>CC(C)CN1C(=O)COc2cc(F)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US05350743,CCOP(=O)(O)C(N1CCC(=O)CC1)P(=O)(O)O.C[Mg]Br>>CCOP(=O)(O)C(N1CCC(C)(O)CC1)P(=O)(O)O,,C1CCOC1,,,,test
US20140228343A1,ClC[C@@H]1CO1.Oc1cccc(-c2cccc3cccnc23)c1>>c1cc(OC[C@H]2CO2)cc(-c2cccc3cccnc23)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20160075698A1,O=C(/C=C/c1cnc2cc(F)ccc2c1)CCCCc1ccc2c(n1)NCCC2>>OC(/C=C/c1cnc2cc(F)ccc2c1)CCCCc1ccc2c(n1)NCCC2,,CO,,Cl,[BH4-].[Na+],test
US20070191293A1,CS(=O)(=O)OC1CC=CC1.c1ccc2c(c1)CC[C@@H]2Nc1ncnc2[nH]ccc12>>C1=CCC(n2ccc3c(N[C@H]4CCc5ccccc54)ncnc32)C1,,CN(C)C=O,,Cc1ccccc1,O=C([O-])[O-].[Cs+].[Cs+],test
US20100152207A1,COC(=O)CC#N.Nc1cccc(F)c1C=O>>N#Cc1cc2c(F)cccc2[nH]c1=O,,CO,,C[O-].[Na+],,test
US20080076917A1,CC[Si](Cl)(CC)CC.OCc1c(Br)sc2c(-c3cccnc3)ncn12>>CC[Si](CC)(CC)OCc1c(Br)sc2c(-c3cccnc3)ncn12,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,,test
US20040063679A1,C=CC(C)(C)CC=O.COC(=O)C(NC(=O)OCc1ccccc1)P(=O)(OC)OC>>C=CC(C)(C)CC=C(NC(=O)OCc1ccccc1)C(=O)OC,,C1CCOC1,ClCCl,C1CCC2=NCCCN2CC1,,test
US04495187,CCOC(OCC)(OCC)c1ccccc1.NNc1nc2ccccc2nc1Cl>>Clc1nc2ccccc2n2c(-c3ccccc3)nnc12,,CCO,,,,test
US20120208840A1,CC(C)c1ccnc(C(C)O)c1F>>CC(=O)c1nccc(C(C)C)c1F,O=[Mn]=O,Cc1ccccc1,,,,test
US06107253,C=CCBr.Nc1c([N+](=O)[O-])cnn1-c1ncc(C(F)(F)F)cc1Cl>>C=CCNc1c([N+](=O)[O-])cnn1-c1ncc(C(F)(F)F)cc1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070225275A1,COC(=O)C(C)(C)c1ccc(Nc2nc(C(C)C)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1>>CC(C)c1nc2c(c(Nc3ccc(C(C)(C)CO)cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140128373A1,CC(C)CS(=O)(=O)Cl.Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Br)cc23)c1F>>CC(C)CS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Br)cc23)c1F,,C1CCOC1,,CCOC(C)=O,c1ccncc1,test
US04032521,O=CO.c1ccc(CNCc2ccccc2)cc1>>O=CN(Cc1ccccc1)Cc1ccccc1,,O=CO,,CC(=O)OC(C)=O,,test
US20160257951A1,CCCCCCCCCCC(O)CCCCCCC/C=C\C[C@@H](CCCCCC)O[Si](C)(C)C(C)(C)C.CN(C)CCCO.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCCCCCCCCCC(CCCCCCC/C=C\C[C@@H](CCCCCC)O[Si](C)(C)C(C)(C)C)OC(=O)OCCCN(C)C,,Cc1ccccc1,,c1ccncc1,,test
US20130131043A1,C[Mg]Br.O=CC1CCCCC1>>CC(O)C1CCCCC1,,C1CCOC1,CCOCC,,,test
US20090131502A1,O=C(n1ccnc1)n1ccnc1.OC1(Cc2ccccc2)CCC1>>O=C(OC1(Cc2ccccc2)CCC1)n1ccnc1,,ClCCl,,,,test
US20080096940A1,CC(C)Oc1nc2cc(OC(C)(C)C)cc([C@@H](O)CNC(C)(C)Cc3ccccc3)c2s1>>CC(C)(Cc1ccccc1)NC[C@H](O)c1cc(O)cc2[nH]c(=O)sc12,,O=CO,,,,test
US20150119392A1,CNc1ncc2cc(OS(=O)(=O)C(F)(F)F)c(C)nc2n1.COC(C)(C)CCNC(=O)Nc1cc(B2OC(C)(C)C(C)(C)O2)c(C)cc1F>>CNc1ncc2cc(-c3cc(NC(=O)NCCC(C)(C)OC)c(F)cc3C)c(C)nc2n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])O.[Na+],,test
US05482936,CCOCn1c(CCCCCCl)nc2c(N(Cc3ccccc3)Cc3ccccc3)nc3ccccc3c21>>ClCCCCCc1nc2c(N(Cc3ccccc3)Cc3ccccc3)nc3ccccc3c2[nH]1,,Cl,ClCCl,[Na+].[OH-],,test
US20140221330A1,CC(C)(C)[Si](C)(C)Oc1ccc(CC2=C([C@@H]3CC[C@H](O[Si](C)(C)C(C)(C)C)CC3)C(=O)OC2=O)cc1.CCOCC.CO>>COC(=O)/C(Cc1ccc(O[Si](C)(C)C(C)(C)C)cc1)=C(\C(=O)OC)[C@@H]1CC[C@H](O[Si](C)(C)C(C)(C)C)CC1,,CO,,C[Si](C)(C)C=[N+]=[N-],,test
US20070173505A1,Nc1nc(Cl)cc2nc(-c3ccco3)nn12.c1ccc(CN2CCC3CNCC32)cc1>>Nc1nc(N2CC3CCN(Cc4ccccc4)C3C2)cc2nc(-c3ccco3)nn12,,CS(C)=O,,[Cs+].[F-],,test
US20070032525A1,COCCNC(=O)c1cccc2[nH]c(NCC3CCN(C(=O)OC(C)(C)C)CC3)nc12>>COCCNC(=O)c1cccc2[nH]c(NCC3CCNCC3)nc12,,CO,,C1COCCO1,Cl,test
US20100152234A1,O=C(O)CCC(=O)NCc1cccc(C(F)(F)F)c1.c1csc(C2NCCc3ccccc32)c1>>O=C(CCC(=O)N1CCc2ccccc2C1c1cccs1)NCc1cccc(C(F)(F)F)c1,,C1CCOC1,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080090818A1,CCOC(=O)c1cccc2ccsc12>>O=C(O)c1cccc2ccsc12,,CO,O,[Na+].[OH-],,test
US04745116,C=[N+]=[N-].CCc1cc([N+](=O)[O-])cc2nocc12>>CCc1cc([N+](=O)[O-])c(C)c2nocc12,,CCOCC,,,,test
US05583222,COCOc1ccc(C(=O)N[C@@H]2CN(C(=O)OC(C)(C)C)CCC[C@H]2OC(=O)c2ccc(C(=O)c3c(OCOC)ccc(OC)c3F)cc2)cc1.Cl>>COc1ccc(O)c(C(=O)c2ccc(C(=O)O[C@@H]3CCCNC[C@H]3NC(=O)c3ccc(O)cc3)cc2)c1F.Cl,,COCCOC,,CC(C)O,,test
US04686213,CCOC(=O)C(=NO)c1c[nH]c2c(CC)cccc12>>CCOC(=O)C(N)c1c[nH]c2c(CC)cccc12,[Pd],CCO,,Cl,,test
US20140275087A1,COCN(Cc1ccccc1)C[Si](C)(C)C.COc1ccc(/C=C/[N+](=O)[O-])cc1>>COc1ccc([C@@H]2CN(Cc3ccccc3)C[C@H]2[N+](=O)[O-])cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130059834A1,CC(=O)CCCl.CC(C)(CO[Si](C)(C)C(C)(C)C)NC(=O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ncc(-c3n[nH]c4cc(F)ccc34)nc12>>CC(=O)CCn1nc(-c2cnc3c(n2)c(C(=O)NC(C)(C)CO[Si](C)(C)C(C)(C)C)cn3C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ccc(F)cc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080293767A1,CCOC(=O)c1ccc(C)n(C(C)C)c1=O.CI>>CCOC(=O)c1ccc(CC)n(C(C)C)c1=O,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20030036652A1,Nc1cc(C(F)(F)F)cnc1N.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2cc(C(F)(F)F)cnc2[nH]1,,ClCCl,,,,test
US20130005707A1,CN1C(=O)C(C)(C)c2ccc([N+](=O)[O-])cc21>>CN1C(=O)C(C)(C)c2ccc(N)cc21,[Pd],CCOC(C)=O,CO,[H][H],,test
US20070270421A1,CN1CC(N2CCN(C(=O)Nc3cc(Oc4ccc(N)cc4)ccn3)CC2)C1.O=C=NC(=O)Cc1ccccc1>>CN1CC(N2CCN(C(=O)Nc3cc(Oc4ccc(NC(=O)NC(=O)Cc5ccccc5)cc4)ccn3)CC2)C1,,C1CCOC1,CCCCCC,CCOCC,,test
US06107329,CO.O=C(O)C1NCCS1>>COC(=O)C1NCCS1,,CO,,C[Si](C)(C)Cl,,test
US20160016966A1,CC(=O)Nc1cc(B2OC(C)(C)C(C)(C)O2)ccn1.C[C@@H]1CN(S(C)(=O)=O)CCN1Cc1cc2c(=O)n(C)cc(Br)c2o1>>CC(=O)Nc1cc(-c2cn(C)c(=O)c3cc(CN4CCN(S(C)(=O)=O)C[C@H]4C)oc23)ccn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20160229814A1,CCI.O=C1COc2cc([N+](=O)[O-])ccc2N1>>CCN1C(=O)COc2cc([N+](=O)[O-])ccc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070244132A1,CCOC(=O)c1cccc(Nc2ncnc3cc[nH]c23)c1>>O=C(O)c1cccc(Nc2ncnc3cc[nH]c23)c1,,CO,,Cl,[Na+].[OH-],test
US20140045862A1,Cn1nccc1[C@H]1CC(=O)CC[C@@H]1OC(=O)c1ccccc1>>Cn1nccc1[C@H]1C[C@@H](O)CC[C@@H]1OC(=O)c1ccccc1,,CCO,,O,[BH4-].[Na+],test
US20090088457A1,Cc1cccc(CNC2CC2)c1C.N#CCC(=O)O>>Cc1cccc(CN(C(=O)CC#N)C2CC2)c1C,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130261081A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.c1ccc(CN2CCN[C@@H]3CCCC[C@@H]32)cc1>>CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)[C@H]2CCCC[C@H]21,,CO,,,,test
US04931379,C=Cc1ccc(O)cc1.CC(=O)c1ccc([N+](=O)[O-])cc1.CC(O)c1ccc([N+](=O)[O-])cc1.O=C(Cl)OC(Cl)(Cl)Cl>>CC(O)c1ccc([N+](=O)[O-])cc1.CC(OC(=O)OC=Cc1ccccc1)c1ccc([N+](=O)[O-])cc1,,CCO,,[BH4-].[Na+],,test
US07238716B2,COC(=O)c1cncc(OCc2cccc(OCc3nc(-c4ccccc4)oc3C)c2)c1>>Cc1oc(-c2ccccc2)nc1COc1cccc(COc2cncc(CO)c2)c1,,C1CCOC1,,[H-].[Na+],,test
US20110159431A1,C=C(C)C(=O)Cl.Oc1cccc2ccccc12>>C=C(C)C(=O)Oc1cccc2ccccc12,,O,,CCN(CC)CC,ClCCl,test
US20040038970A1,CC(C)(C)OC(=O)N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)cs1.Cl>>Cl.N[C@H](Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)cs1,,CCOC(C)=O,,,,test
US20150274720A1,C1CCOC1.CN(C)C=O.O=S(=O)(c1ccccc1)n1ccc2c(Br)ccnc21.[Li]CCCC>>CC(C)NC(C)C.O=Cc1cc2c(Br)ccnc2n1S(=O)(=O)c1ccccc1,,C1CCOC1,,,,test
US20160129002A1,COc1cn(-c2ccc(Nc3nc(COCC(F)(F)F)cc(C(C)=O)n3)cc2OC)cn1>>COc1cn(-c2ccc(Nc3nc(COCC(F)(F)F)cc(C(C)O)n3)cc2OC)cn1,,CC(C)=O,,CCO,,test
US20130296358A1,CC(C)(C)OC(=O)N1CCCC2(C1)C(=O)N(Cc1ncco1)CC2c1ccc(F)cc1>>O=C1N(Cc2ncco2)CC(c2ccc(F)cc2)C12CCCNC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150329524A1,CCC(=O)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(Br)cc2F)C1.CI>>CCC(=O)N1CC[C@@H](Cc2nn(C)c(=O)n2-c2ccc(Br)cc2F)C1,,CCOC(C)=O,O,CN(C)C=O,[H-].[Na+],test
US08394902B2,CC(C)(C)N.Cc1ccccc1NCc1ccc2ccccc2c1-c1cccc(C=O)n1.[Li]c1ccccc1>>Cc1ccccc1NCc1ccc2ccccc2c1-c1cccc(C(NC(C)(C)C)c2ccccc2)n1,,C1CCOC1,,CCOCC,O,test
US20090099187A1,COc1ccc(S(=O)(=O)Nc2cccc(C(F)(F)F)c2)c2c1C[C@@H](NC(=O)C(F)(F)F)CC2>>COc1ccc(S(=O)(=O)Nc2cccc(C(F)(F)F)c2)c2c1C[C@@H](N)CC2,,CO,,Cl,[Na+].[OH-],test
US04697037,Cc1ccc(C(=O)O)cc1Br.Sc1ccccc1>>Cc1ccc(C(=O)O)cc1Sc1ccccc1,,c1ccc2ncccc2c1,,,,test
US04217269,O=C(Cl)COc1ccccc1.O=C(O)[C@@H]1CCCN1>>O=C(O)[C@@H]1CCCN1C(=O)COc1ccccc1,,O,,c1ccncc1,,test
US20130150376A1,CNC1=CS(=O)(=O)N(c2cccc(F)c2)[C@@]12CCN(C(=O)OCc1ccccc1)[C@@H](C)C2>>CNC1=CS(=O)(=O)N(c2cccc(F)c2)[C@@]12CCN[C@@H](C)C2,[Pd],CCO,,,,test
US20160108059A1,COc1c(C(=O)NCc2ccc(F)cc2)n2c(cc1=O)CCC2CO.CS(=O)(=O)Cl>>COc1c(C(=O)NCc2ccc(F)cc2)n2c(cc1=O)CCC2COS(C)(=O)=O,,ClCCl,,O,,test
US20090253760A1,CCCCCCCCc1ccc2c(c1)CC(Br)C2=O.CCOC(=O)C(NC(C)=O)C(=O)OCC>>CCCCCCCCc1ccc2c(c1)CC(C(NC(C)=O)(C(=O)OCC)C(=O)OCC)C2=O,,CN(C)C=O,,[H-].[Na+],,test
US20070191293A1,CC(C)(C)[Si](C)(C)OC[C@@H]1C[C@@H](n2ccc3c(N[C@H]4CCc5ccccc54)ncnc32)[C@H](O)[C@@H]1O.S=C(n1ccnc1)n1ccnc1>>CC(C)(C)[Si](C)(C)OC[C@@H]1C[C@@H](n2ccc3c(N[C@H]4CCc5ccccc54)ncnc32)[C@@H]2OC(=S)O[C@@H]21,,CN(C)C=O,,,,test
US05371099,CCOC(=O)CC(C)=O.Nc1ccc(SC(F)(F)F)cc1>>CC(=O)CC(=O)Nc1ccc(SC(F)(F)F)cc1,,Cc1ccccc1,,,,test
US20120208815A1,Nc1cnccc1Cl.O=C(Cl)OCc1ccccc1>>O=C(Nc1cnccc1Cl)OCc1ccccc1,,C1CCOC1,,c1ccncc1,,test
US20120208213A1,CCCCCn1cc(C(=O)c2cccc3ccccc23)c2cc(OC)ccc21>>CCCCCn1cc(C(=O)c2cccc3ccccc23)c2cc(O)ccc21,,O,,Br,,test
US20110003801A1,CCCCNS(=O)(=O)c1ccccc1.Cn1c(Cl)nc2ccccc21>>CCCCN(c1nc2ccccc2n1C)S(=O)(=O)c1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US20050009817A1,C[Si](C)(C)CCOC(=O)CCC(=O)c1c[nH]c2ccc(Cl)cc12.Clc1nc(-c2ccccc2)cc(-c2ccccc2)n1>>C[Si](C)(C)CCOC(=O)CCC(=O)c1cn(-c2nc(-c3ccccc3)cc(-c3ccccc3)n2)c2ccc(Cl)cc12,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[K+].[K+],,test
US20120208800A1,COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCN(C(=O)[O-])C(C)(C)C)c1nnc(C)n1-2.O=C(O)C(F)(F)F>>COc1ccc2c(c1)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCN)c1nnc(C)n1-2.O=C(O)C(F)(F)F,,ClCCl,,,,test
US05939436,CC(C)(C)OC(=O)N1CCC(Br)CC1.[N-]=[N+]=[N-]>>CC(C)(C)OC(=O)N1CCC(N=[N+]=[N-])CC1,,CN(C)C=O,,O,,test
US20040006141A1,CCOC(=O)C(CCOc1ccccc1)Cc1ccc(OCCN=[N+]=[N-])cc1>>CCOC(=O)C(CCOc1ccccc1)Cc1ccc(OCCN)cc1,[Pd],,,,,test
US20130150339A1,COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(Cl)nccc3c2)cc1.OB(O)c1ccc(F)cc1O>>COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(-c4ccc(F)cc4O)nccc3c2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04599344,C=C1C(=O)C2CCN1CC2.Cl[Cu].Clc1ccc(CCBr)cc1>>Cl.O=C1C2CCN(CC2)C1CCCc1ccc(Cl)cc1,Cl[Cu],CCOCC,,[Mg],,test
US20100261728A1,COc1ccc(C2NCCc3ccccc32)cc1.O=C=Nc1ccc(F)cc1>>COc1ccc(C2c3ccccc3CCN2C(=O)Nc2ccc(F)cc2)cc1,,ClCCl,,,,test
US20050187223A1,CI.Nc1nc(-c2ccccc2)cc(=O)[nH]1>>Cn1c(N)nc(-c2ccccc2)cc1=O,,CCO,,[K+].[OH-],,test
US20140179682A1,CC1(C)CCc2nc3cc(C(=O)O)ccc3c(=O)n2C1.CCN=C=NCCCN(C)C.N=C(NO)c1ccccn1>>Nc1noc(C2CN3CCC2C3)n1,,CN(C)C=O,O,On1nnc2ccccc21,,test
US20130267729A1,CC(C)(C)OC(=O)NCC(=O)O.ClCCl.NCC(F)(F)F>>Cl.NCC(=O)NCC(F)(F)F,,ClCCl,,CC(C)COC(=O)Cl,CCN(CC)CC,test
US06015825,c1ccc(Cn2ccnn2)cc1>>c1ccc(Cn2ccnn2)cc1,,CCOC(C)=O,O,Cl,[Na+].[OH-],test
US20090036474A1,COc1cc2ncnc(Oc3cnn(CC(=O)Nc4cccc(CN(C(=O)OC(C)(C)C)C5CC5)c4)c3)c2cc1OC>>COc1cc2ncnc(Oc3cnn(CC(=O)Nc4cccc(CNC5CC5)c4)c3)c2cc1OC,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150031648A1,Cn1cccc1C#N.O=C1CCC(=O)N1Br>>Cn1cc(Br)cc1C#N,,CN(C)C=O,,,,test
US04024255,CCn1cc(C(=O)O)c(=O)c2ccc(Cl)nc21.O=S(Cl)Cl>>CCn1cc(C(=O)Cl)c(=O)c2ccc(Cl)nc21,,Cc1ccccc1,,,,test
US20140275528A1,CCO.Cn1c(=O)c2c(nc(CC(=O)O)n2Cc2cccc(Br)c2)n(C)c1=O>>CCOC(=O)Cc1nc2c(c(=O)n(C)c(=O)n2C)n1Cc1cccc(Br)c1,O=S(=O)(O)O,,,,,test
US20040167176A1,BrC(Br)(Br)Br.CC(C)Cc1cc(-c2ccc(CO)cc2)c(S(=O)(=O)NC(C)(C)C)s1>>CC(C)Cc1cc(-c2ccc(CBr)cc2)c(S(=O)(=O)NC(C)(C)C)s1,,CCOC(C)=O,CN(C)C=O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US03943124,CCCCI.C[C@]12CC(=O)[C@H]3[C@@H](CC[C@H]4C[C@H](O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)O>>CCCCOC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C,,CC(C)=O,,CCN(CC)CC,,test
US20100056506A1,CC(=O)Nc1c(C)ccc(C(=O)O)c1[N+](=O)[O-].[OH-]>>Cc1ccc(C(=O)O)c([N+](=O)[O-])c1O,,O,,Cl,,test
US20130274255A1,CC(=O)Nc1cccc(-c2nn(COCC[Si](C)(C)C)c3c2Cc2sccc2-3)c1.Cl>>Cl.Nc1cccc(-c2n[nH]c3c2Cc2sccc2-3)c1,,CO,,,,test
US05506219,CC(=O)c1ccccc1.CC(C)C=O>>CC(C)C(O)CC(=O)c1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20090299077A1,CN1CCC[C@@H]1Cc1c[nH]c2ccc(CCS(=O)(=O)c3ccccc3)cc12.Cc1ccc(S(=O)(=O)O)cc1>>CN1CCC[C@@H]1Cc1c[nH]c2ccc(CCS(=O)(=O)c3ccccc3)cc12.Cc1ccc(S(=O)(=O)O)cc1,,CC(C)=O,,,,test
US05686445,CN(C)C=C1CCN(C(=O)c2ccc([N+](=O)[O-])cc2)c2ccccc2C1=O.N=CN>>O=C(c1ccc([N+](=O)[O-])cc1)N1CCc2cncnc2-c2ccccc21,,CO,,Cl,C[O-].[Na+],test
US20060148858A1,CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO.COC(=O)Cc1cccc(Br)c1O>>CCCc1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCOc1c(Br)cccc1CC(=O)OC,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20080171743A1,C[C@H]1COCCN1c1cc(COS(C)(=O)=O)nc(-c2ccc(NC(=O)Nc3ccccc3)cc2)n1.Sc1ccccc1>>C[C@H]1COCCN1c1cc(CSc2ccccc2)nc(-c2ccc(NC(=O)Nc3ccccc3)cc2)n1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20090023702A1,BrBr.O=c1cc(O)cc[nH]1>>O=c1[nH]cc(Br)c(O)c1Br,,O,,Br,,test
US20060178386A1,C=CCN.NC(=O)c1ccc(C(F)(F)F)cc1F>>C=CCNc1cc(C(F)(F)F)ccc1C(N)=O,,CCOC(C)=O,,CC(=O)N(C)C,O=C([O-])[O-].[K+].[K+],test
US04737513,O=C(Cl)c1ccccc1.O=Cc1cc[nH]c1>>O=Cc1ccn(C(=O)c2ccccc2)c1,,C1CCOC1,O,[H-].[Na+],,test
US20040116487A1,CCO[C@H](C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1)[C@H](O)c1ccc(OCc2ccccc2)cc1C(F)(F)F.CO>>CCO[C@H](C(=O)OC)[C@H](O)c1ccc(OCc2ccccc2)cc1C(F)(F)F,,CO,,C[O-].[Na+],,test
US20030078251A1,COC(=O)c1cc2cc(NC(=O)C[C@H]3O[C@H](c4cccc(OC)c4OC)c4cc(Cl)ccc4N(CC(C)(C)COC(C)=O)C3=O)cc(OC(C)C)c2o1>>COc1cccc([C@H]2O[C@H](CC(=O)Nc3cc(OC(C)C)c4oc(C(=O)O)cc4c3)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20020177605A1,C1COCCN1.COC(=O)[C@H](Cc1ccc(Nc2nc(-c3ccccc3)cc3ccccc23)cc1)Nc1c(OC(C)C)c(=O)c1=O>>O=C(O)[C@H](Cc1ccc(Nc2nc(-c3ccccc3)cc3ccccc23)cc1)Nc1c(N2CCOCC2)c(=O)c1=O,,CO,,CC(=O)O,,test
US20020077271A1,COS(C)(=O)=O.Cc1cc(Nc2ccccc2)nc(N)n1>>CS(=O)(=O)[O-].Cc1cc(Nc2ccccc2)nc(N)[n+]1C,,CCO,,,,test
US20060293308A1,CC(C)(C)OC(=O)N1CCN(c2ccc([N+](=O)[O-])nc2)CC1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.O=[N+]([O-])c1ccc(N2CCNCC2)cn1,,ClCCl,,,,test
US20070112077A1,CC(CO)CCCC(C)(C)O.CCCCCC.Cc1ccc(S(=O)(=O)OC[C@H](C)COCOCc2ccccc2)cc1>>C[C@H](/C=C\CCO)CCCC(C)(C)O,,O,,,,test
US20130289058A1,CCOC(=O)C1(C(=O)OCC)CC=C(c2ccc(Cl)cc2)CC1>>OCC1(CO)CC=C(c2ccc(Cl)cc2)CC1,,C1CCOC1,,,,test
US20080009530A1,CCCCCCOC(=O)Cl.CCCCOc1cc(CCS(N)(=O)=O)n(Cc2ccc(Cl)cc2Cl)n1.CN(C)c1ccncc1>>CCCCOc1cc(CCS(=O)(=O)NC(=O)OCc2ccccc2)n(Cc2ccc(Cl)cc2Cl)n1,CN(C)c1ccncc1,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,,test
US20090163488A1,CC(C)(C)OC(=O)Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)ccc1Cl>>Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)ccc1Cl,,O=C(O)C(F)(F)F,,,,test
US20050203078A1,CN(C)C1CCNC1.N#Cc1ccc(F)c(Cl)c1>>CN(C)C1CCN(c2ccc(C#N)cc2Cl)C1,,CN(C)C=O,,O,[H-].[Na+],test
US20150175623A1,CC(=O)OC(C)=O.Cc1c(-c2csc3ncnc(Cl)c23)ccc(O[Si](C(C)C)(C(C)C)C(C)C)c1Cl>>CC(=O)c1sc2ncnc(Cl)c2c1-c1ccc(O[Si](C(C)C)(C(C)C)C(C)C)c(Cl)c1C,,C1CCOC1,,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US20040077669A1,CC#CCOc1cc(NCC(F)(F)C(F)(F)F)ncn1.CCI>>CC#CCOc1cc(N(CC)CC(F)(F)C(F)(F)F)ncn1,,CN(C)C=O,,[H-].[Na+],,test
US05206235,CC(C)=CC(=O)Cl.N[C@@H]1CCc2ccccc2N(Cc2ccc(-c3ccccc3-c3nnn[nH]3)cc2)C1=O>>CC(C)=CC(=O)N[C@@H]1CCc2ccccc2N(Cc2ccc(-c3ccccc3-c3nnn[nH]3)cc2)C1=O,,ClCCl,,CCN(CC)CC,Cl,test
US20120004203A1,CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(N(CC(C)C)C(=O)OCc3ccccc3)nc2N1c1cccc(C(F)(F)F)c1>>CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(NCC(C)C)nc2N1c1cccc(C(F)(F)F)c1,[Pd],CO,,,,test
US20110039848A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.Clc1ccc(Cl)nn1>>CC(=O)c1ccc(Cl)nn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,Cl,,test
US20060148858A1,CC(C)C(=O)Cl.COC(=O)Cc1cccc(OC)c1OCCCc1cn(-c2ccc(N)cn2)nc1C(C)C>>COc1cccc(CC(=O)O)c1OCCCc1cn(-c2ccc(NC(=O)C(C)C)cn2)nc1C(C)C,,O,,CN(C)C=O,,test
US09394297B2,C[C@H]1NC(=O)c2cc(B3OC(C)(C)C(C)(C)O3)[nH]c21.Cc1nc2cccc(Br)c2nc1N[C@H]1CCC[C@@H](N)C1>>Cc1nc2cccc(-c3cc4c([nH]3)[C@@H](C)NC4=O)c2nc1N[C@H]1CCC[C@@H](N)C1,,C1COCCO1,,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US06346527B1,CCOC(=O)C1=Cc2cc(N)ccc2OCC1.CSSC>>CCOC(=O)C1=Cc2cc(SC)ccc2OCC1,,CC#N,,CCOC(C)=O,O,test
US20060111413A1,CC(C)(C)OC(=O)CBr.[N-]=[N+]=N[C@@H]1Cc2ccccc2C[C@H]1O>>CC(C)(C)OC(=O)CO[C@@H]1Cc2ccccc2C[C@H]1N=[N+]=[N-],,C1CCOC1,,[H-].[Na+],,test
US20080182802A1,C=C(C)C[Si](C)(C)C.CCc1ccc(Cc2cc([C@]3(O)O[C@H](COCc4ccccc4)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)c(OC)cc2Cl)cc1>>C=C(C)C[C@@]1(c2cc(Cc3ccc(CC)cc3)c(Cl)cc2OC)O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1,,ClCCl,,,,test
US05234946,BrP(Br)Br.CC(C)=CCc1cccc(CO)c1>>CC(C)=CCc1cccc(CBr)c1,,CCOCC,,c1ccncc1,,test
US05591762,CCCc1nc2c(C)cc(-c3cn(Cc4ccccc4)cn3)cc2n1Cc1ccc(-c2ccccc2C(C)(C)C)cc1.O=C(O)C(F)(F)F>>CCCc1nc2c(C)cc(-c3cn(Cc4ccccc4)cn3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1,,ClCCl,,,,test
US20040048916A1,O=C1c2ccc(C(F)(F)F)cc2C(=O)N1CC(F)(F)F>>O=C1c2ccc(C(F)(F)F)cc2C(O)N1CC(F)(F)F,,O,,,,test
US20120115868A1,Cn1nnc(-c2ccc(F)cc2)c1COc1cc(C(=O)O)on1.NC1CCOCC1>>Cn1nnc(-c2ccc(F)cc2)c1COc1cc(C(=O)NC2CCOCC2)on1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20040132727A1,CC(O)c1ccc(OC(F)(F)F)cc1.COc1cc2nccc(Oc3ccc(N)c(C)c3C)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2nccc(Oc3ccc(NC(=O)OC(C)c4cccc(OC(F)(F)F)c4)c(C)c3C)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20130225554A1,CC(C)(C)OC(=O)NC(=O)Cl.NCCON1C(=O)c2ccccc2C1=O>>CC(C)(C)OC(=O)NC(=O)NCCON1C(=O)c2ccccc2C1=O,,ClCCl,,CCN(CC)CC,Cl,test
US20160016914A1,CC(=O)Cl.COC(=O)c1noc2cc(N)ccc12>>COC(=O)c1noc2cc(NC(C)=O)ccc12,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20020107262A1,CC(C)(C)OC(=O)NCCCCN.Cc1nc(Cl)c([N+](=O)[O-])c(Cl)c1C>>Cc1nc(Cl)c([N+](=O)[O-])c(CCCCNC(=O)OC(C)(C)C)c1C,,CCOC(C)=O,,CCN(CC)CC,CN(C)C=O,test
US20060135578A1,CCOC(=O)c1cn(-c2ccccc2)nc1O.COc1cc(CCl)ccc1OCc1nc(-c2ccccc2)oc1C>>CCOC(=O)c1cn(-c2ccccc2)nc1OCc1ccc(OCc2nc(-c3ccccc3)oc2C)c(OC)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20010056105A1,COC(=O)c1ccc(SC#Cc2ccc3c(c2)C(C)(C)CCC3(C)C)cc1>>CC1(C)CCC(C)(C)c2cc(C#CSc3ccc(C(=O)O)cc3)ccc21,,C1CCOC1,,,,test
US04247549,C1CN(C2CC2)CCN1.CC(C)(C)OC(=O)ON=C(C#N)c1ccccc1>>CC(C)(C)OC(=O)N1CCN(C2CC2)CC1,,CCOC(C)=O,,Cl,,test
US20090221556A1,N.Oc1nc2c(Cl)nc3ccccc3c2n1Cc1ccccc1>>Nc1nc2ccccc2c2c1nc(O)n2Cc1ccccc1,,CO,,,,test
US04880781,CC[C@H](C)[C@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC.Cc1ccc(S(=O)(=O)n2cnc(C[C@H](NC(=O)OC(C)(C)C)C(=O)O)c2)cc1>>CC[C@H](C)[C@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1cn(S(=O)(=O)c2ccc(C)cc2)cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC,CC(=O)O,ClCCl,O=C(O)C(F)(F)F,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20120157430A1,CC(=O)c1cc(Cl)c(C)c(N2CCCC2=O)c1-c1cccc(F)c1.[NH4+]>>Cc1c(Cl)cc(C(C)N)c(-c2cccc(F)c2)c1N1CCCC1=O,,CC#N,CO,[BH3-]C#N.[Na+],,test
US04260779,O=C(Nc1cccc(Cl)c1)Oc1ccccc1.O=C1Cc2ccccc2S1>>O=C(Nc1cccc(Cl)c1)C1C(=O)Sc2ccccc21,,CN(C)P(=O)(N(C)C)N(C)C,,Cl,[H-].[Na+],test
US20040087555A1,CC(C)C=CO.Cc1ccc(S(=O)(=O)Cl)cc1>>C=C(C)CCOS(=O)(=O)c1ccc(C)cc1,CN(C)c1ccncc1,ClCCl,,CCCCCC,,test
US20110081365A1,Nc1nc2cc([N+](=O)[O-])ccc2c2cccnc12>>Nc1ccc2c(c1)nc(N)c1ncccc12,[Pd],CCO,ClCCl,,,test
US20100016299A1,CCOC(=O)C1CCN(C(=O)CC2OC(c3cccc(OC)c3OC)c3cc(Cl)ccc3-c3c2noc3C(C)C)CC1>>COc1cccc(C2OC(CC(=O)N3CCC(C(=O)O)CC3)c3noc(C(C)C)c3-c3ccc(Cl)cc32)c1OC,,C1COCCO1,,Cl,O,test
US20040138269A1,CCOC(=O)c1c(C)cc(C)n1-c1ccc(C(=O)O)cc1.COc1cccc(CN)c1>>CCOC(=O)c1[nH]c(C)c(-c2ccc(C(=O)NCc3cccc(OC)c3)cc2)c1C,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,O=C([O-])O.[Na+],test
US20030166639A1,C=Cc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3ccnc(C)c3)c2)cc1C(F)(F)F>>C=Cc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3ccnc(C)c3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140343053A1,O=c1n(CCc2ccc3ncccc3n2)nc2c(Br)cccn12.OB(O)c1ccncc1>>O=c1n(CCc2ccc3ncccc3n2)nc2c(-c3ccncc3)cccn12,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,C1COCCO1,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140179689A1,NCCc1ccccc1.O=C(O)c1ccc2[nH]ccc2c1>>O=C(NCCc1ccccc1)c1ccc2[nH]ccc2c1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US05321027,CC(=O)OC(C)=O.Nc1ccc(C(=O)N2CCN(CCc3ccc(Cl)cc3)CC2)c(Cl)c1>>CC(=O)Nc1ccc(C(=O)N2CCN(CCc3ccc(Cl)cc3)CC2)c(Cl)c1,,ClC(Cl)Cl,,,,test
US05134111,CCOC(=O)/C(C)=C\c1cc(OC)c(OCOC)c2c(CC)cccc12>>CCc1cccc2c(/C=C(/C)C(=O)O)cc(OC)c(OCOC)c12,,CCO,,Cl,[K+].[OH-],test
US20040102484A1,COc1ccc(NS(=O)(=O)c2ccc(OCC(=O)OCCS(=O)(=O)c3ccc(C)cc3)c(OCC(=O)OCCS(=O)(=O)c3ccc(C)cc3)c2)c([N+](=O)[O-])c1>>COc1ccc(NS(=O)(=O)c2ccc(OCC(=O)OCCS(=O)(=O)c3ccc(C)cc3)c(OCC(=O)OCCS(=O)(=O)c3ccc(C)cc3)c2)c(N)c1,O=[Pt],,,,,test
US20110183978A1,CC(C)Br.On1cc(Br)c(-c2ccc(F)cc2)n1>>CC(C)On1cc(Br)c(-c2ccc(F)cc2)n1,,CN(C)C=O,,[H-].[Na+],,test
US20130150325A1,Cc1cc(/C(F)=C/c2ccc(CN(C(C)C)C(C)C)cc2)n[nH]1.ClCc1ccnc(N2CCN(C3CC3)CC2)c1>>Cc1cc(/C(F)=C/c2ccc(CN(C(C)C)C(C)C)cc2)nn1Cc1ccnc(N2CCN(C3CC3)CC2)c1,,C1CCOC1,CCOC(C)=O,CC(C)(C)[O-].[K+],,test
US20120283257A1,CC(C)(C)OC(=O)N1CCN(C(C)(C)C(=O)N2CCCC2)CC1.Cl>>CC(C)(C(=O)N1CCCC1)N1CCNCC1.Cl,,CCOCC,ClCCl,,,test
US06376530B1,CC=CNC(=O)c1ccc(OC(F)(F)F)cc1.CI>>Cc1cc(OC(F)(F)F)ccc1C(N)=O,,C1CCOC1,,[Li]CCCC,O=C([O-])O.[Na+],test
US20040266826A1,CC(C)(C)OC(=O)C[C@]1(c2ccc(Br)s2)CCCCS1(=O)=O.OB(O)c1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)C[C@]1(c2ccc(-c3ccc(B(O)O)cc3)s2)CCCCS1(=O)=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20070037809A1,Nc1ncccn1.O=C(CBr)c1ccccc1[N+](=O)[O-]>>O=[N+]([O-])c1ccccc1-c1cn2cccnc2n1,,CC(C)=O,,,,test
US20110046118A1,Nc1cnc(N2CCN3CCC2CC3)nc1.O=C(Cl)c1ccccc1Oc1ccccc1>>Cl.O=C(Nc1cnc(N2CCN3CCC2CC3)nc1)c1ccccc1Oc1ccccc1,[Pd],CCO,,,,test
US07417051B2,O=C(O)C=Cc1ccc(-c2ccccc2)cc1.OCc1cc(C(O)CNCCCCCCOCCCCc2ccccc2)ccc1O>>O=C([O-])C=Cc1ccc(-c2ccccc2)cc1.OCc1cc(C(O)CNCCCCCCOCCCCc2ccccc2)ccc1O,,CCOC(C)=O,,,,test
US20020022605A1,CC(C)(C)OC(=O)N(C[C@H](O)COc1ccc(OCc2ccccc2)cc1)C1CN(C(c2ccccc2)c2ccccc2)C1>>CC(C)(C)OC(=O)N(C[C@H](O)COc1ccc(O)cc1)C1CNC1,[Pd],CO,,O=C[O-].[NH4+],,test
US20090105302A1,C=CCCCCN(C)C(=O)C1CC(O)CC1C(=O)NC1(C(=O)OCC)CC1C=C>>C=CCCCCN(C)C(=O)C1CC(O)CC1C(=O)NC1(C(=O)O)CC1C=C,,CN(C)C=O,,Cl,[Li+].[OH-],test
US20150210630A1,C[C@H](NC(=O)OC(C)(C)C)C(=O)c1ncc(Cl)cc1Cl.NO>>C[C@H](NC(=O)OC(C)(C)C)C(=NO)c1ncc(Cl)cc1Cl,,CCO,,Cl,c1ccncc1,test
US20100029650A1,CC(C)c1noc(N2CCC(C(C)Oc3ccc(-c4ccc(S(C)(=O)=O)cc4)nc3)CC2)n1>>CC(C)c1noc(N2CCC([C@H](C)Oc3ccc(-c4ccc(S(C)(=O)=O)cc4)nc3)CC2)n1,,CO,,O=C=O,,test
US05556860,CC(=O)OC(C)=O.O=C1Nc2ccccc2C(c2ccccc2)N1C1CCN(Cc2cccc(O)c2)CC1>>CC(=O)Oc1cccc(CN2CCC(N3C(=O)Nc4ccccc4C3c3ccccc3)CC2)c1,,c1ccncc1,,O,,test
US06040433,C[C@@H]1O[C@H](Sc2ccccc2)[C@@H](OC(=O)C(C)(C)C)[C@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C.O=C(OO)c1cccc(Cl)c1>>C[C@@H]1O[C@H](S(=O)c2ccccc2)[C@@H](OC(=O)C(C)(C)C)[C@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C,,ClCCl,,CSC,,test
US20100152450A1,CC(C)(C)OC(=O)N1CC[C@H]1COc1cncc([C@H]2C[C@@H]2CCO)c1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCC[C@H]2C[C@@H]2c2cncc(OC[C@@H]3CCN3)c2)cc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20060128702A1,NCC(=O)c1ccccc1.O=C(Cl)c1ccc(F)cc1>>CC(=O)c1ccccc1NC(=O)c1ccc(F)cc1,,ClCCl,,CCN(CC)CC,,test
US20110190278A1,CC#CNCCN1C(=O)C(C)(COC#CC)Oc2cc(C(F)(F)F)c(C(=O)N(C(C)C)[C@@H]3CCCN(C(=O)OC(C)(C)C)C3)cc21>>CC#CNCCN1C(=O)C(C)(CO)Oc2cc(C(F)(F)F)c(C(=O)N(C(C)C)[C@@H]3CCCN(C(=O)OC(C)(C)C)C3)cc21,,CO,,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20110257151A1,CC1(C)Cc2c(ccc(F)c2C(=O)O)NC1c1cccc(N2CCOCC2)c1.NS(=O)(=O)C1CC1>>CC1(C)Cc2c(ccc(F)c2C(=O)NS(=O)(=O)C2CC2)NC1c1cccc(N2CCOCC2)c1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,[H-].[Na+],test
US06387926B1,Nc1cnc2ccccc2c1.O=S(=O)(Cl)c1ccccc1>>O=S(=O)(Nc1cnc2ccccc2c1)c1ccccc1,,CC#N,CCOC(C)=O,c1ccncc1,,test
US20150141433A1,BrBr.COC(=O)c1cnc(C)c(C(F)(F)F)n1>>COC(=O)c1cnc(CBr)c(C(F)(F)F)n1,,CC(=O)O,,,,test
US20150266881A1,Cl.Cl.Cn1cc(NC(=O)c2cccc([C@@H]3C[C@H]3N)c2)cn1.O=C1CCC1>>Cl.Cl.Cn1cc(NC(=O)c2cccc([C@@H]3C[C@H]3NC3CCC3)c2)cn1,,CC(=O)O,CO,O=C([O-])O.[Na+],,test
US20120196872A1,Nc1ccc2c(c1)CC1(C2)C(=O)Nc2ncccc21.O=C1CCC(=O)N1Cl>>Nc1cc2c(cc1Cl)CC1(C2)C(=O)Nc2ncccc21,,ClCCl,,,,test
US20140121198A1,N#CC[C@@H]1CC[C@H](Nc2c([N+](=O)[O-])cnc3ccsc23)C1>>N#CC[C@@H]1CC[C@H](Nc2c(N)cnc3ccsc23)C1,[Pd],CO,,,,test
US20160272595A1,CCS(=O)(=O)c1ccc(Cl)cc1N(C(=O)OC(C)(C)C)n1cnc2c(Br)cc(C)cc2c1=O>>CCS(=O)(=O)c1ccc(Cl)cc1Nn1cnc2c(Br)cc(C)cc2c1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100261698A1,Cn1c(-c2cncc(CN)c2)c(C#N)c2ccc(Cl)cc21.O=C1c2ccccc2C(=O)N1CCS(=O)(=O)Cl>>Cn1c(-c2cncc(CNS(=O)(=O)CCN3C(=O)c4ccccc4C3=O)c2)c(C#N)c2ccc(Cl)cc21,,ClCCl,,CCN(CC)CC,,test
US20140088101A1,CCCC[Sn](CCCC)(CCCC)c1ccccc1.COC(=O)c1ncc2c(cc(Br)c(=O)n2CC2CCCCC2)c1O>>COC(=O)c1ncc2c(cc(-c3ccccc3)c(=O)n2CC2CCCCC2)c1O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,CN(C)C=O,Cl,O,test
US20120238549A1,C[S+](C)(C)=O.Cc1ncccc1NC(=O)c1cc2n(c1)CCC[C@@H]1CC(=O)CC[C@]21Cc1ccccc1.Cc1ncccc1NC(=O)c1cc2n(c1)CCC[C@H]1CC(=O)CC[C@@]21Cc1ccccc1>>Cc1ncccc1NC(=O)c1cc2n(c1)CCC[C@@H]1C[C@@]3(CC[C@]21Cc1ccccc1)CO3.Cc1ncccc1NC(=O)c1cc2n(c1)CCC[C@H]1C[C@]3(CC[C@@]21Cc1ccccc1)CO3,,C1CCOC1,CS(C)=O,[H-].[Na+],,test
US20010000038A1,CC(C)c1ccccc1.O=C(Cl)CCCCl>>CC(C)c1ccc(C(=O)CCCCl)cc1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US05095113,CNC(C)=O.N#C[N-]C#N.O=P(Cl)(Cl)Cl>>Cc1nc(Cl)nc(Cl)n1,,Cc1ccccc1,,Cl,,test
US20050288273A1,CC(C)(C)O.CCN=C=NCCCN(C)C.NC[C@H]1CN(c2ccc3c(c2)CCCc2cn[nH]c2-3)C(=O)O1.O=C(O)CC1CC1>>O=C(CC1CC1)NC[C@H]1CN(c2ccc3c(c2)CCCc2cnn(C(=O)CC4CC4)c2-3)C(=O)O1,,CCN(CC)CC,,Cl,,test
US03941806,Cc1c(-c2ccccc2)c2cc(Cl)cc3c2n1CC3.O=[O+][O-]>>O=C(c1ccccc1)c1cc(Cl)cc2c1NCC2,,O,,CC(=O)O,,test
US20080280875A1,CC(C)(C)OC(=O)c1cc(Oc2ccc(S(C)(=O)=O)cc2)c2c(c1)OC(CO)C2.CI>>COCC1Cc2c(Oc3ccc(S(C)(=O)=O)cc3)cc(C(=O)OC(C)(C)C)cc2O1,,C1CCOC1,,[H-].[Na+],,test
US20050020587A1,CC(=O)N1CCC(NC(=O)OC(C)(C)C)C1>>CC(=O)N1CCC(N)C1,,ClCCl,O,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],test
US20020103229A1,CCN(CC)CC.Cc1cc(C)[nH]n1.NNC(=O)c1ccc2[nH]nc(-c3ccc(F)cc3)c2c1>>Nc1nnc(-c2ccc3[nH]nc(-c4ccc(F)cc4)c3c2)[nH]1,,CCCCO,O,,,test
US05180728,Cc1c(C(C)N)ncn1C(c1ccccc1)(c1ccccc1)c1ccccc1.Cc1c(CC=O)n(S(=O)(=O)c2ccccc2)c2ccccc12>>Cc1c(CCNC(C)c2ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c2C)n(S(=O)(=O)c2ccccc2)c2ccccc12,,CO,O,CC(=O)O,[BH3-]C#N.[Na+],test
US05888941,Cc1nc(-c2ccc(C#N)cc2)sc1C(=O)N(CCO)[C@H](C)[C@](O)(Cn1cncn1)c1ccc(F)cc1F>>Cc1nc(-c2ccc(C#N)cc2)sc1C(=O)N1CCO[C@@](Cn2cncn2)(c2ccc(F)cc2F)[C@H]1C,,C1CCOC1,,CCCCP(CCCC)CCCC,,test
US04919708,CC(C)Oc1cc(NNC(=N)C(F)(F)F)c(Cl)cc1Cl.O=C(Cl)Cl>>CC(C)Oc1cc(-n2nc(C(F)(F)F)[nH]c2=O)c(Cl)cc1Cl,,Cc1ccccc1,O,CCN(CC)CC,Cl,test
US05268389,CCCOC(=O)c1cc(N)ccc1Cl.Cc1ccccc1C(=O)Cl>>CCCOC(=O)c1cc(NC(=O)c2ccccc2C)ccc1Cl,,ClCCl,,CCN(CC)CC,,test
US20060052597A1,CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(OCCCN3CCCCC3)cc2C(F)(F)F)CC1.Cl.ClCCl>>Cl.Cl.O=C(c1ccc(OCCCN2CCCCC2)cc1C(F)(F)F)N1CCNCC1,,C1COCCO1,ClCCl,,,test
US04873236,CCCN(CCC)CC1CCCN(CCN)C1.O=C1Nc2cccnc2N(C(=O)Cl)c2ccccc21>>CCCN(CCC)CC1CCCN(CCNC(=O)N2c3ccccc3C(=O)Nc3cccnc32)C1,,CC#N,,,,test
US20080132551A1,CCOc1ccc(N)c(-c2ncco2)c1.O=C(Cl)Oc1ccccc1>>CCOc1ccc(NC(=O)Oc2ccccc2)c(-c2ncco2)c1,,ClCCl,,c1ccncc1,,test
US20050227960A1,CC(C)(C)OC(=O)N1CC2CC(NC(=O)CNC(=O)c3cccc(C(F)(F)F)c3)C(CO)C2C1.c1ccc(SSc2ccccc2)cc1>>CC(C)(C)OC(=O)N1CC2CC(NC(=O)CNC(=O)c3cccc(C(F)(F)F)c3)C(CSc3ccccc3)C2C1,,C1CCOC1,,CCCCP(CCCC)CCCC,,test
US20100234351A1,OCC1=Cc2c(ncnc2Nc2ccc(Oc3cccc(C(F)(F)F)c3)c(Cl)c2)NCC1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>[N-]=[N+]=NCC1=Cc2c(ncnc2Nc2ccc(Oc3cccc(C(F)(F)F)c3)c(Cl)c2)NCC1,,C1CCOC1,,O,,test
US20150133422A1,COc1ccc(CN)c(OC)c1.O=S(=O)(c1ccccc1)n1cc(-c2cnn(-c3ccc(Cl)nn3)c2)c2ccc(F)cc21>>COc1ccc(CNc2ccc(-n3cc(-c4cn(S(=O)(=O)c5ccccc5)c5cc(F)ccc45)cn3)nn2)c(OC)c1,,CCOC(C)=O,CN1CCCC1=O,,,test
US04151172,COC(=O)C(C)P(=O)(O)O.Cc1ccc(N=NNCc2ccccc2)cc1>>COC(=O)C(C)P(=O)(OCc1ccccc1)OCc1ccccc1,,CCOC(C)=O,CCOCC,CCCCCC,,test
US04599406,CN1C(C(=O)O)=C(OC(=O)C=Cc2ccccc2)c2ccccc2S1(=O)=O.Nc1ccccn1>>CN1C(C(=O)Nc2ccccn2)=C(OC(=O)C=Cc2ccccc2)c2ccccc2S1(=O)=O,,CCOCC,,ClCCl,,test
US06982274B2,O=C1CC(I)C(=O)N1.O=[N+]([O-])c1ccc2[nH]ncc2c1>>O=[N+]([O-])c1ccc2[nH]nc(I)c2c1,,CN(C)C=O,,CCOCC,O,test
US20080076758A1,CC(C)(O)C(C)(C)O.CC(C)OB(OC(C)C)OC(C)C.COc1ccc(COc2cc(Br)cc(F)c2F)cc1>>COc1ccc(COc2cc(B3OC(C)(C)C(C)(C)O3)cc(F)c2F)cc1,,C1CCOC1,Cc1ccccc1,[Li]CCCC,,test
US20100125058A1,Cc1c(C(=O)O)cc2ccc(Cl)cc2c1O>>Cc1c(CO)cc2ccc(Cl)cc2c1O,,C1CCOC1,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20010003782A1,COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C(C)(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C>>COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C(C)(C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,,CO,,[BH4-].[Na+],,test
US20160137647A1,COc1cc(C(=O)O)cc2nc(NC(CF)c3cccc(Cl)c3)oc12.C[C@@H]1COC(C)(CCO)CN1>>COc1cc(C(=O)N2CC(C)(CCO)OC[C@H]2C)cc2nc(NC(CF)c3cccc(Cl)c3)oc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070037809A1,C1CCNC1.O=[N+]([O-])c1ccccc1-c1cn2c(CO)csc2n1>>O=[N+]([O-])c1ccccc1-c1cn2c(CN3CCCC3)csc2n1,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20140249104A1,COC(=O)C[C@](CF)(N[S@](=O)C(C)(C)C)c1cc(Br)ccc1F>>CC(C)(C)[S@@](=O)N[C@@](CF)(CCO)c1cc(Br)ccc1F,,CO,,C1CCOC1,[BH4-].[Na+],test
US04259324,CC(=O)O[C@@H]1[C@H](C)O[C@H](S)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.CCCCCCCCCCCCCCCCBr>>CCCCCCCCCCCCCCCCS[C@H]1O[C@@H](C)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,ClCCl,,CCN(CC)CC,,test
US20120010190A1,COC(=O)c1ccc(-c2ccc(C(CC(=O)c3ccc(=O)n(C)c3)c3ccccc3C)cc2)cc1F>>Cc1ccccc1C(CC(=O)c1ccc(=O)n(C)c1)c1ccc(-c2ccc(C(=O)O)c(F)c2)cc1,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20050124605A1,COc1ccc(CN2C(=O)CN3C(=O)[C@@H](Oc4nc(C)cc(C)n4)[C@]3(c3cccc(C(F)(F)F)c3)c3ccccc32)cc1.[Li]O>>COc1ccc(CN2C(=O)CN[C@](c3cccc(C(F)(F)F)c3)([C@H](Oc3nc(C)cc(C)n3)C(=O)O)c3ccccc32)cc1,,C1CCOC1,CO,Cl,O,test
US20140194431A1,CC(C)N1CCn2c(Cc3ccc(Cl)cc3-c3ccncc3)nc(=O)c(OCc3ccccc3)c2C1=O>>CC(C)N1CCn2c(Cc3ccc(Cl)cc3-c3ccncc3)nc(=O)c(O)c2C1=O,,CC(=O)O,,O=S(=O)(O)O,,test
US20160159808A1,CC(C)(O)C(NC(=O)c1cnn2ccc(Cl)nc12)c1ccc(OC(F)(F)F)c(F)c1.c1cn[nH]c1>>CC(C)(O)C(NC(=O)c1cnn2ccc(-n3cccn3)nc12)c1ccc(OC(F)(F)F)c(F)c1,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140275172A1,CC(=O)C(C)Cl.CC(C)=O.COC(=O)c1cc(O)cc(Cl)c1>>CC(=O)C(C)OC(=O)c1cc(Cl)cc(OC(C)C(C)=O)c1,,CCOCC,O,[I-].[K+],,test
US04492599,COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(C)nc(OC)n1>>COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)O)n1,,CS(C)=O,,O,CC(C)(C)[O-].[K+],test
US05240923,ClCc1ccncc1.O=S1(=O)NCC(O)c2ccsc21>>O=S1(=O)c2sccc2C(O)CN1Cc1ccncc1,,CN(C)C=O,,[H-].[Na+],,test
US08586591B2,C[C@H](Nc1nc(Cl)cc(N2CC(=O)NC(=O)C2)n1)c1ccc(F)cc1.Nc1cnccn1>>C[C@H](Nc1nc(Nc2cnccn2)cc(N2CC(=O)NC(=O)C2)n1)c1ccc(F)cc1,,CCOC(C)=O,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20060142336A1,C=C(C)C.O=C(O)C(CBr)C1CCCC1>>CC(C)(C)OC(=O)C(CBr)C1CCCC1,O=S(=O)(O)O,ClCCl,,O=C([O-])O.[Na+],,test
US04748163,Nc1ccc(C(=O)O)cc1N.O=C(O)C(F)(F)F>>O=C(O)c1ccc2[nH]c(C(F)(F)F)nc2c1,,Cl,,,,test
US04649146,BrBr.CC(=O)c1sc(O)nc1C>>Cc1nc(O)sc1C(=O)CBr,,CC(=O)O,ClCCl,O,,test
US20080096875A1,BrCCCCCOc1ccccc1.O=[N+]([O-])c1cccc(O)c1>>O=[N+]([O-])c1cccc(OCCCCCOc2ccccc2)c1,,CN1CCCC1=O,,[I-].[K+],,test
US04929618,CCOC(=O)CCCBr.Clc1ccc(C(OC2CCNCC2)c2ccccn2)cc1>>CCOC(=O)CCCN1CCC(OC(c2ccc(Cl)cc2)c2ccccn2)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090298816A1,COc1cc(-c2nc3c(Cl)cc4c(Br)n[nH]c4c3c(=O)o2)n(-c2ncccc2Cl)n1.NC1(C2CC2)CC1>>COc1cc(C(=O)Nc2c(Cl)cc3c(Br)n[nH]c3c2C(=O)NC2(C3CC3)CC2)n(-c2ncccc2Cl)n1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20150018341A1,CCC(=C(c1ccc(O)cc1)c1ccc(OCCCl)cc1)c1ccc2oc(Cl)cc2c1.CNC>>CCC(=C(c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccc2oc(Cl)cc2c1,,CO,,,,test
US20080255144A1,CC(O)c1ccc(N2CCN(C(=O)c3cc(S(C)(=O)=O)ccc3-c3ccccc3)CC2)c(F)c1.CI.CN(C)C=O>>COC.COC(C)c1ccc(N2CCN(C(=O)c3cc(S(C)(=O)=O)ccc3-c3ccccc3)CC2)c(F)c1,,CN(C)C=O,,[H-].[Na+],,test
US05128340,Nc1nc(-c2cccnc2)cs1.O=C1CCC(=O)N1Cl>>Nc1nc(-c2cccnc2)c(Cl)s1,,CN(C)C=O,,,,test
US20050197365A1,C#CCNC1CCc2ccc([N+](=O)[O-])cc21.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>C#CCN(C(=O)OC(C)(C)C)C1CCc2ccc([N+](=O)[O-])cc21,,CCO,,CCCCCC,,test
US04195154,Oc1ccccc1.c1ccc(C2=NCCO2)cc1>>O=C(NCCOc1ccccc1)c1ccccc1,,O,,CCOCC,,test
US20090181959A1,C[Si](C)(C)CCOCn1ccc2c(-c3cnn(C4CCC(=CC#N)CC4)c3)ncnc21.O=C(O)C(F)(F)F>>N#CC=C1CCC(n2cc(-c3ncnc4[nH]ccc34)cn2)CC1.O=C(O)C(F)(F)F,,CC#N,O,[NH4+].[OH-],,test
US20140329812A1,BrC(Br)(Br)Br.COC(=O)c1nnn(-c2cc(C(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)c1-c1ccc(CO)cc1>>COC(=O)c1nnn(-c2cc(C(C)C)c(OCc3ccccc3)cc2OCc2ccccc2)c1-c1ccc(CBr)cc1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100273770A1,CC(C)(C)OC(=O)N1Cc2cc(C(=N)NO)ccc2OCC1CO.CC(C)Oc1ccc(C(=O)O)cc1Cl>>CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)CN(C(=O)OC(C)(C)C)C(CO)CO4)no2)cc1Cl,,CCOC(C)=O,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
US20140323468A1,COC(=O)c1ccncc1-c1cnc2c(c1)CCCN2C(=O)OC(C)(C)C>>COC(=O)c1ccncc1-c1cnc2c(c1)CCCN2,,CO,Cl,,,test
US20080318963A1,CCOC(=O)Nc1nc2ccc(Cl)cc2nc1OC.c1ccc(N2CCNCC2)cc1>>COc1nc2cc(Cl)ccc2nc1NC(=O)N1CCN(c2ccccc2)CC1,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20020193385A1,O=[N+]([O-])c1ccc(F)c(-c2ccncc2)c1>>Nc1ccc(F)c(-c2ccncc2)c1,O=[Pt]=O,CCO,CCOC(C)=O,,,test
US20110201629A1,O=C(NC1CCC(COS(=O)(=O)C(F)(F)F)CC1)c1cc(C(F)(F)F)ccc1Cl.O=C1Cc2cc(Cl)ccc2N1>>O=C(N[C@@H]1CC[C@@H](CN2C(=O)Cc3cc(Cl)ccc32)CC1)c1cc(C(F)(F)F)ccc1Cl,,CN(C)C=O,O,[H-].[Na+],,test
US20080027051A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1ccc2nc(-c3ccc(N)nc3)oc2c1>>COc1ccc2nc(-c3ccc(NC(=O)OC(C)(C)C)nc3)oc2c1,,C1CCOC1,,,,test
US20110294793A1,CC(C)CNC(=O)c1cc(Cl)cc(C(=O)NCC(C)C)c1>>CC(C)CNCc1cc(Cl)cc(CNCC(C)C)c1,,CO,,B,Cl,test
US07465808B2,Cc1ccc(-c2cc(CC(CBr)c3cccc(C)c3)nn2-c2ccc(C)cc2)cc1.[C-]#N>>Cc1ccc(-c2cc(CC(CC#N)c3cccc(C)c3)nn2-c2ccc(C)cc2)cc1,,O,,CN(C)C=O,,test
US20020099152A1,CC(C)(C)C(=O)Cl.CCOC(=O)C(C)Br>>CCOC(=O)C(C)C(=O)C(C)(C)C,,CCOCC,,,,test
US05017212,COc1cc(OC)nc(N)n1.O=C=NS(=O)(=O)Cl>>COc1cc(OC)nc(NC(=O)NS(=O)(=O)Cl)n1,,C1CCOC1,,,,test
US20100280268A1,CCOc1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C(=O)OC)c2)ccc1N.Cc1ccc(S(=O)(=O)Cl)cc1>>CCOc1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C(=O)OC)c2)ccc1NS(=O)(=O)c1ccc(C)cc1,,ClCCl,,c1ccncc1,,test
US04778790,CC(C)(C)OC(=O)CN1C[C@@H](c2cccs2)SC[C@H](N[C@@H](CCCCN2C(=O)c3ccccc3C2=O)C(=O)OC(C)(C)C)C1=O>>CC(C)(C)OC(=O)CN1C[C@@H](c2cccs2)SC[C@H](N[C@@H](CCCCN)C(=O)OC(C)(C)C)C1=O,,CCO,ClCCl,NN,O,test
US04255575,CC(=O)Cl.Oc1ccccc1-c1nnn[nH]1>>CC(=O)c1ccc(O)c(-c2nnn[nH]2)c1,,ClCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20050080262A1,COC(=O)c1ccc(OCCCl)c(OC)c1>>COc1cc(C(=O)O)ccc1OCCCl,,CO,,Cl,[Na+].[OH-],test
US20130210844A1,CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)O)c1.CC(C)(C)Nc1ncnc2c(N)cccc12>>CC(C)(C)Nc1ncnc2c(NC(=O)c3cc(CNC(=O)C(C)(C)C)ccc3Cl)cccc12,,C1CCOC1,,CCN(C(C)C)C(C)C,O=S(Cl)Cl,test
US20070004704A1,COC(=O)c1ccc(Cl)cc1N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1>>Cc1oc(-c2ccccc2)nc1CCOc1ccc(S(=O)(=O)Nc2cc(Cl)ccc2C(=O)O)cc1,,C1COCCO1,,[Na+].[OH-],,test
US06951906B1,Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.[Li]CCCC>>[Li]Oc1c(C(C)(C)C)cc(C)cc1C(C)(C)C,,Cc1ccccc1,,,,test
US05536725,CC(C)(c1cccc(Cl)c1)C1CCC(=O)CC1>>CC(C)(C1=CCC(=O)CC1)c1cccc(Cl)c1,[Pd],CCO,,,,test
US20120190649A1,CC(C)(C)OC(=O)N1CCc2cc(OC3CCC(C(C)(C)C)CC3)ccc21>>CC(C)(C)[C@@H]1CC[C@@H](Oc2ccc3c(c2)CCN3)CC1,,C1CCOC1,,C1COCCO1,Cl,test
US20070167631A1,CCOC(=O)c1ccc(C(F)(F)F)c(C)n1.O=C1CCC(=O)N1Br>>CCOC(=O)c1ccc(C(F)(F)F)c(CBr)n1,,ClC(Cl)(Cl)Cl,,,,test
US20120142717A1,COc1ncc(Cc2c[nH]c(=S)[nH]c2=O)cn1.N#Cc1cc(CCl)ccc1Oc1ccc(F)c(C(F)(F)F)c1>>COc1ncc(Cc2c[nH]c(SCc3ccc(Oc4ccc(F)c(C(F)(F)F)c4)c(C#N)c3)nc2=O)cn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20060178381A1,CC(C)(C)OC(=O)N1Cc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C1.Cc1csc(I)n1>>Cc1csc(-c2ccc3c(c2)CN(C(=O)OC(C)(C)C)C3)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080076771A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN(C)C(=O)CSc1nsc(N)n1>>CN(C)C(=O)CSc1nsc(NC(=O)OC(C)(C)C)n1,CN(C)c1ccncc1,C1CCOC1,,,,test
US20040157885A1,COC(=O)N1CCC[C@@H](c2cccc(OC(C)(C)C(=O)OCc3ccccc3)c2)C1>>COC(=O)N1CCC[C@@H](c2cccc(OC(C)(C)C(=O)O)c2)C1,[Pd],CO,,,,test
US20020193616A1,C[C@H](SCCC(C)(C)O)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C>>C[C@H](SCCC(C)(C)O)C1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20050288273A1,CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCC(C(=O)c2cccnc2)C3=O)C(=O)O1.NN>>CC(=O)NC[C@H]1CN(c2ccc3c(c2)CCCc2c(-c4cccnc4)n[nH]c2-3)C(=O)O1,,CCO,,O,,test
US20080261967A1,C=CCCC(O)Cc1cc(F)ccc1OC.O=C1CCC(=O)N1Br>>COc1ccc(F)cc1CC1CCC(CBr)O1,,ClCCl,,,,test
US20080280855A1,CNC(=O)c1cc2c(nc(C)n2C)c(O)c1CC[C@@H](O)c1ccccc1>>CNC(=O)c1cc2c(nc(C)n2C)c2c1CC[C@@H](c1ccccc1)O2,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080214448A1,COC(=O)CCCCc1nc(-c2cc(Cl)ccc2OC)co1>>O=C(O)CCCCc1nc(-c2cc(Cl)ccc2O)co1,,ClCCl,,BrB(Br)Br,,test
US20140171427A1,CCOc1ccccc1F.O=C=O>>CCOc1cccc(C(=O)O)c1F,,C1CCOC1,Cl,[Li]CCCC,,test
US05239082,CC(C)c1cccc(C(C)C)c1N.CCO.O=C(O)CS(=O)(=O)O>>CCOC(=O)CS(=O)(=O)Nc1c(C(C)C)cccc1C(C)C,,ClCCl,,O=P(Cl)(Cl)Cl,,test
US20110039840A1,CCCCN1C(=O)c2cc(/C=C/C(=O)OC)ccc2OC12CCN(C(=O)OC(C)(C)C)CC2.Cl>>CCCCN1C(=O)c2cc(/C=C/C(=O)OC)ccc2OC12CCNCC2.Cl,,C1COCCO1,,,,test
US04160036,CC(=O)CCc1ccc(F)cc1.C[Mg]I>>CC(C)(O)CCc1ccc(F)cc1,,CCOCC,,O=S(=O)(O)O,,test
US20120258953A1,CC(C)(C)OC(=O)N1CCC(O)(C(F)(F)F)CC1>>OC1(C(F)(F)F)CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120088767A1,COC(=O)c1cc(N2CCOCC2)cc2nc(C(F)F)[nH]c12.Cc1c(CBr)cccc1C(F)(F)F>>COC(=O)c1cc(N2CCOCC2)cc2c1nc(C(F)F)n2Cc1cccc(C(F)(F)F)c1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130059849A1,CC(C)n1nccc1N.CCOC(=O)C(=O)CC(=O)c1ccc(SC)cc1>>CCOC(=O)c1cc(-c2ccc(SC)cc2)nc2c1cnn2C(C)C,,CC(=O)O,,c1ccccc1,,test
US04435407,Cn1cccc1C(=O)CC#N.O=C=Nc1cccnc1>>Cn1cccc1C(=O)C(C#N)C(=O)Nc1cccnc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20090209540A1,C=Cc1cnc(Cl)c(Cl)c1.Cc1ccc(B(O)O)cn1>>C=Cc1cnc(-c2ccc(C)nc2)c(Cl)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20080090813A1,CS(=O)(=O)Nc1cc(Br)cc(C(F)(F)F)c1.C[Sn](C)(C)c1cc(CCCOCc2ccccc2)nc(C#N)n1>>CS(=O)(=O)Nc1cc(-c2cc(CCCOCc3ccccc3)nc(C#N)n2)cc(C(F)(F)F)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,CN(C)C=O,,,test
US20150119373A1,C=C(C)[C@@H]1CC[C@]2(C(=O)N[C@@H]3C[C@H](C(=O)N4CCCCC4)C3(C)C)CC[C@]3(C)[C@H](CC[C@H]4[C@@]3(C)CC[C@H]3C(C)(C)[C@@H](OC(=O)CC(C)(C)C(=O)O)CC[C@@]34C)[C@@H]12.C[N+]1([O-])CCOCC1.O=[Os](=O)(=O)=O>>CC(C)(CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2CC[C@@H]2[C@H]4[C@H](C(C)(O)CO)CC[C@]4(C(=O)N[C@@H]4C[C@H](C(=O)N5CCCCC5)C4(C)C)CC[C@]23C)C1(C)C)C(=O)O,O=[Os](=O)(=O)=O,CC(C)=O,ClCCl,O,,test
US20080085890A1,CC(C)CC(=O)Cl.Nc1ccc(CNC=C2C(=O)NC(=O)c3ccccc32)cc1>>CC(C)CC(=O)Nc1ccc(CNC=C2C(=O)NC(=O)c3ccccc32)cc1,,CN(C)C=O,c1ccncc1,,,test
US20110092531A1,CN1CC2(CCN(C(=O)OCc3ccccc3)CC2)c2cccc(Cl)c21>>CN1CC2(CCNCC2)c2cccc(Cl)c21,,O=C(O)C(F)(F)F,,,,test
US04604390,COc1ccc2c(=O)c3c(Cl)ccc([N+](=O)[O-])c3oc2c1>>O=c1c2ccc(O)cc2oc2c([N+](=O)[O-])ccc(Cl)c12,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US05080708,CCc1nsc(C(=O)NC(C)C)c1C(=O)OC>>CCc1nsc(C(=O)NC(C)C)c1C(=O)O,,CCO,O,[K+].[OH-],,test
US20070287701A1,CC(C)(C)OC(=O)N1CC(=O)[C@H](CNC(=O)OCc2ccccc2)C1.NO>>CC(C)(C)OC(=O)N1C/C(=N\O)[C@H](CNC(=O)OCc2ccccc2)C1,,CO,,Cl,CC(=O)[O-].[Na+],test
US20100240671A1,CN1CCN(c2cc(-c3ccc4c(c3)CN(C(=O)OC(C)(C)C)CC4)nc(N)n2)CC1.Cl>>CN1CCN(c2cc(-c3ccc4c(c3)CNCC4)nc(N)n2)CC1.Cl,,C1COCCO1,CO,,,test
US20070060644A1,CC(=O)c1ccc(C)cc1C.O=Cc1ccccc1>>Cc1ccc(C(=O)C=Cc2ccccc2)c(C)c1,,CO,O,Cl,[Na+].[OH-],test
US20100249151A1,CC(C)(C)OC(=O)NN.COc1cc(OC)c(-c2nc3ncccn3c2Nc2c(Cl)cccc2Cl)c(C(=O)O)c1>>COc1cc(OC)c(-c2nc3ncccn3c2Nc2c(Cl)cccc2Cl)c(C(=O)NNC(=O)OC(C)(C)C)c1,,CN(C)C=O,,O,,test
US20070032478A1,Nc1ccc(N2CCOCC2)cc1.O=C1Nc2cc(C(=O)c3cccc(NC(=O)c4cccs4)c3)ccc2C1=CO>>O=C1Nc2cc(C(=O)c3cccc(NC(=O)c4cccs4)c3)ccc2C1=CNc1ccc(N2CCOCC2)cc1,,C1CCOC1,,,,test
US20100056507A1,C[Si](C)(C)C=[N+]=[N-].O=C(O)CCc1ccc([N+](=O)[O-])cc1>>NNC(=O)CCc1ccc([N+](=O)[O-])cc1,,CO,,,,test
US20140179664A1,CCOC(=O)Cn1cc(Nc2ncc(Cl)c(N[C@H](CO)c3ccccc3F)n2)cn1.N>>NC(=O)Cn1cc(Nc2ncc(Cl)c(N[C@H](CO)c3ccccc3F)n2)cn1,,CO,,,,test
US20090286783A1,O=Cc1cccc(NS(=O)(=O)c2ccc(C(F)(F)F)cc2)c1F.c1ncc2cc[nH]c2n1>>O=S(=O)(Nc1cccc(C(O)c2c[nH]c3ncncc23)c1F)c1ccc(C(F)(F)F)cc1,,CO,,O,[K+].[OH-],test
US20070197512A1,CC(C)[C@@H](Br)C[N-]c1cc(Cl)cc(Cl)c1O.O=C([O-])[O-]>>CC(C)[C@@H]1Oc2c(Cl)cc(Cl)cc2NC1=O,,CN(C)C=O,,O,,test
US06107321,O=C1C2CNCC2C(=O)N1Cc1ccccc1>>c1ccc(CN2C[C@@H]3CNC[C@@H]3C2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20140011856A1,CCN(CC)CCNC(=O)c1c(C)[nH]c2c1CCC/C2=C1/C(=O)Nc2ccc(F)cc21.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>CCN(CC)CCNC(=O)c1c(C)[nH]c2c1CCC/C2=C1/C(=O)Nc2ccc(F)cc21.O=C(O)[C@H](O)[C@@H](O)C(=O)O,,ClCCl,,CC#N,,test
US20160207883A1,II.c1ccc(N2CC(OCCOC3CCCCO3)C2)cc1>>Ic1ccc(N2CC(OCCOC3CCCCO3)C2)cc1,,ClCCl,O,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20070213341A1,CCOC(=O)Cl.O=C1Nc2cc(Cl)ccc2/C1=C/C1CCCCC1>>CCOC(=O)N1C(=O)/C(=C\C2CCCCC2)c2ccc(Cl)cc21,,ClCCl,,CCN(CC)CC,,test
US20080200523A1,[N-]=[N+]=NCCCCCCCc1ccccc1>>NCCCCCCCc1ccccc1,[Pd],CCO,,,,test
US20120208798A1,CC(=O)N1c2ccc(-c3cn(CC(=O)OC(C)(C)C)cn3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C.O=C(O)C(F)(F)F>>CC(=O)N1c2ccc(-c3cn(CC(=O)O)cn3)cc2[C@H](NC(=O)OC(C)C)C[C@@H]1C.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20140336415A1,COc1ccccc1N.O=[N+]([O-])c1c(Cl)cccc1Cl>>COc1ccccc1Nc1cccc(Cl)c1[N+](=O)[O-],,C1CCOC1,O,Cl,[H-].[Na+],test
US20020099208A1,NOCCF.O=C1Nc2ncccc2C1=O>>O=C1Nc2ncccc2C1=NOCCF,,CS(C)=O,,Cl,,test
US06031015,CCOC(=O)c1cc(OCCCCCCCCCCOC(C)=O)c(C(=O)OCC)cc1OCCCCCCCCCCOC(C)=O>>O=C(O)c1cc(OCCCCCCCCCCO)c(C(=O)O)cc1OCCCCCCCCCCO,,CCO,O,Cl,[K+].[OH-],test
US04283532,CNC.O=C(Cl)Cc1ccccc1>>CN(C)C(=O)Cc1ccccc1,,c1ccccc1,,,,test
US04785101,COC(=O)CC(C)C(=O)Cl.Oc1nc2ccccc2[nH]1>>CC(CC(=O)O)C(=O)c1ccc2nc(O)[nH]c2c1,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20040132727A1,CC(O)c1ccccc1F.COc1cc2ncnc(Oc3ccc(N)c(Cl)c3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2ncnc(Oc3ccc(NC(=O)OC(C)c4ccccc4F)c(Cl)c3)c2cc1OC,,ClCCl,,CCN(CC)CC,Cc1ccccc1,test
US20080119535A1,CCN(Cc1cn(S(=O)(=O)N(C)C)cn1)c1ccnc(Oc2ccccc2)n1>>CCN(Cc1c[nH]cn1)c1ccnc(Oc2ccccc2)n1,,CCO,Cl,[Na+].[OH-],,test
US03940395,CCOC(=O)CC(=O)OCC.Cc1cccc(C(=N)N)c1>>Cc1cccc(C2=NC(=O)CC(=O)N2)c1,,CCO,,Cl,[Na],test
US20100104532A1,CC(C)C(=O)Nc1nc2c(ncn2C2OC(C=CP(=O)(O)O)C(O)C2O)c(=O)[nH]1>>Nc1nc2c(ncn2C2OC(C=CP(=O)(O)O)C(O)C2O)c(=O)[nH]1,,[NH4+],[OH-],,,test
US20040258619A1,COC(=O)C=C(CC(=O)OC)CC(=O)OC>>COC(=O)CC(CC(=O)OC)CC(=O)OC,[Pd],CO,,O,,test
US05100852,CC=O.CO.COC(C)OC>>C=COC.COC(C)OC,,CO,,,,test
US20150126449A1,Cc1cccc2nn3c(C4CCN(C(=O)OC(C)(C)C)CC4)cc(=O)[nH]c3c12.Cl>>Cc1cccc2nn3c(C4CCNCC4)cc(=O)[nH]c3c12.Cl,,C1COCCO1,CO,,,test
US20040002527A1,NNc1ccc(Cl)cc1.O=C1CCCC(=O)C1>>O=C1CCCC(=NNc2ccc(Cl)cc2)C1,,O,,,,test
US05693635,Nc1ccc(C(=O)N2Cc3ccccc3Cc3ccccc32)cc1.O=C(Cl)c1ccccc1Cl>>O=C(Nc1ccc(C(=O)N2Cc3ccccc3Cc3ccccc32)cc1)c1ccccc1Cl,,ClCCl,,,,test
US20030004169A1,FC(F)(F)c1cc(C2=CCN(Cc3ccccc3)CC2)ccc1Cl>>FC(F)(F)c1cc(C2CCN(Cc3ccccc3)CC2)ccc1Cl,[Pd],CO,,Cl,,test
US20080255114A1,CC[C@H]1CN(Cc2ccccc2)CCN1.COC(=O)c1cccc2oc(Cl)nc12>>CC[C@H]1CN(Cc2ccccc2)CCN1c1nc2c(C(=O)OC)cccc2o1,,COCCOC,,[H-].[Na+],,test
US05189054,CCOC(=O)CNc1cc(F)ccc1C#N>>CCOC(=O)c1[nH]c2cc(F)ccc2c1N,,C1CCOC1,CCOC(C)=O,CC(C)(C)[O-].[K+],,test
US20160046661A1,COc1cc(Cl)c(I)cc1NCC(=O)N1CCN(C/C=C/C(=O)O)CC1.NCCNc1c(NC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(N)nc43)[C@H](O)[C@@H]2O)c(=O)c1=O>>COc1cc(Cl)c(I)cc1NCC(=O)N1CCN(C/C=C/C(=O)NCCNc2c(NC[C@H]3O[C@@H](n4cnc5c(=O)[nH]c(N)nc54)[C@H](O)[C@@H]3O)c(=O)c2=O)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20060173056A1,CC(=O)Cl.CC(C)(C)OC(=O)N1C[C@@H](NCCNc2ccc(C#N)cn2)C[C@H]1C(=O)N1CCSC1>>CC(=O)N(CCNc1ccc(C#N)cn1)[C@H]1C[C@@H](C(=O)N2CCSC2)N(C(=O)OC(C)(C)C)C1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20140127156A1,CC1CCC=C[C@@H]2C[C@@]2(C(=O)NS(=O)(=O)C2(C)CC2)NC(=O)[C@@H]2C[C@@H](Oc3nc4nccn4c4ccccc34)CN2C(=O)[C@@H](NC(=O)OC(C)(C)C)[C@H](C)C1.O=C(O)C(F)(F)F>>CC1CCC=C[C@@H]2C[C@@]2(C(=O)NS(=O)(=O)C2(C)CC2)NC(=O)[C@@H]2C[C@@H](Oc3nc4nccn4c4ccccc34)CN2C(=O)[C@@H](N)[C@H](C)C1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20160115158A1,COc1cc(Cl)nnc1N.N#Cc1cccc(S(=O)(=O)Cl)c1>>COc1cc(Cl)nnc1NS(=O)(=O)c1cccc(C#N)c1,,C1CCOC1,CCOC(C)=O,CC(C)(C)[O-].[K+],,test
US04684739,O=C(CCNCC1COc2ccccc2O1)Nc1ccc2c(c1)OCO2>>c1ccc2c(c1)OCC(CNCCCNc1ccc3c(c1)OCO3)O2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20070287737A1,C[Si](C)(C)c1[nH]nnc1-c1c(Nc2ccc(I)cc2F)cncc1-c1ccccc1F>>Fc1cc(I)ccc1Nc1cncc(-c2ccccc2F)c1-c1c[nH]nn1,,CO,,[Na+].[OH-],,test
US20110263534A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NN1CCN(CCO)CC1>>CC(C)(C)OC(=O)NN1CCN(CCO)CC1,,O,,C1CCOC1,[Li+].[OH-],test
US20080153887A1,CC(=O)c1ccccc1.NNC(=O)c1cc(F)ccc1F>>C/C(=N\NC(=O)c1cc(F)ccc1F)c1ccccc1,,CCOC(C)=O,,,,test
US20150175601A1,CC(C)(C)OC(=O)N1CC[C@H](Oc2ccc([N+](=O)[O-])cc2)C1.Cl>>Cl.O=[N+]([O-])c1ccc(O[C@H]2CCNC2)cc1,,CCOC(C)=O,,,,test
US20130029962A1,C=O.Cc1ccc([N+](=O)[O-])c(C)n1>>Cc1nc(CCO)ccc1[N+](=O)[O-],,CCO,,O,,test
US20140275130A1,CC(C)(C)OC(=O)N1CCc2nc3c(C(=O)On4nnc5ccccc54)c(N)nn3cc2C1.Nc1cnccc1C1CC1>>CC(C)(C)OC(=O)N1CCc2nc3c(C(=O)Nc4cnccc4C4CC4)c(N)nn3cc2C1,,CN1CCCC1=O,,,,test
US20060211720A1,CCc1cc(C=O)c(F)c(O[Si](C)(C)C(C)(C)C)c1.Cn1cnc(-c2ccccc2)n1>>CCc1cc(O[Si](C)(C)C(C)(C)C)c(F)c(C(O)c2nc(-c3ccccc3)nn2C)c1,,C1CCOC1,,[Li]CCCC,,test
US04623660,C1=COCCC1.CC(C(=O)c1ccc(O)cc1)c1ccccc1>>CC(C(=O)c1ccc(OC2CCCCO2)cc1)c1ccccc1,,ClC(Cl)Cl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20070249642A1,Cc1ccsc1-c1cn(CCCCN2C[C@@H]3C[C@]3(c3ccc(C(F)(F)F)cc3)C2)c(=O)[nH]c1=O.Cl>>Cc1ccsc1-c1cn(CCCCN2C[C@@H]3C[C@]3(c3ccc(C(F)(F)F)cc3)C2)c(=O)[nH]c1=O.Cl,,C1COCCO1,,,,test
US06329370B1,COc1ccc2c(Cc3c(Cl)cncc3Cl)nnc(C#CC(C)(C)O)c2c1>>C#Cc1nnc(Cc2c(Cl)cncc2Cl)c2ccc(OC)cc12,,Cc1ccccc1,,[H-].[Na+],,test
US20150087663A1,CC(C)c1nc(-c2c(N)ncnc2Cl)no1.C[C@H](N)c1nc2cccc(Cl)c2c(=O)n1C1CC1>>CC(C)c1nc(-c2c(N)ncnc2N[C@@H](C)c2nc3cccc(Cl)c3c(=O)n2C2CC2)no1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US04073894,COc1ccc(-n2oc(=O)n(CO)c2=O)cc1.O=S(Cl)Cl>>COc1ccc(-n2oc(=O)n(CCl)c2=O)cc1,,Cc1ccccc1,ClC(Cl)Cl,,,test
US20080261978A1,NCc1ccccc1.O=Cc1ccc(S(=O)(=O)N(Cc2ccccc2)Cc2nc3ccccc3[nH]2)cc1>>O=S(=O)(c1ccc(CNCc2ccccc2)cc1)N(Cc1ccccc1)Cc1nc2ccccc2[nH]1,CC(=O)O,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100160369A1,COC(=O)Cc1ccc(C(N)=NO)c(Cl)c1.O=C(O)c1cn2cc(C(F)(F)F)cc(Cl)c2n1>>COC(=O)Cc1ccc(-c2noc(-c3cn4cc(C(F)(F)F)cc(Cl)c4n3)n2)c(Cl)c1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US08367684B2,CCOC(=O)C(C(C)=O)C(C)=O.NC(N)=O>>CCOC(=O)c1c(C)nc(O)nc1C,,CCO,,Cl,,test
US05741926,Nc1cccc(Cl)c1C(=O)O.O=C(Br)CBr>>O=C(CBr)Nc1cccc(Cl)c1C(=O)O,,C1COCCO1,CN(C)C=O,,,test
US06187777B1,CO.Cc1cc(-c2cc3[nH]c(C4CCNC(C)C4)ncc-3n2)c(C)s1.Cl>>Cc1cc(-c2cc3[nH]c(C4CCNC(C)C4)ncc-3n2)c(C)s1.Cl.O,,CO,,CCOC(C)=O,,test
US20100152185A1,ClC(Cl)(Cl)Cl.N#CCNC(=O)c1ccc(OCc2ccc3ccccc3n2)cc1C1(c2ccccc2)CC2CCC1C2>>Clc1c[nH]c(-c2ccc(OCc3ccc4ccccc4n3)cc2C2(c3ccccc3)CC3CCC2C3)n1,,CC#N,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110212998A1,CC(C)C[Mg]Br.CCOC(=O)c1ccnc(Cl)c1>>CCOC(=O)c1ccnc(CC(C)C)c1,,C1CCOC1,,CN1CCCC1=O,,test
US20140364447A1,CC[C@@H](OCc1ccccc1)c1oc2ccccc2c(=O)c1-c1cccc(F)c1>>CC[C@@H](O)c1oc2ccccc2c(=O)c1-c1cccc(F)c1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100240718A1,CCCCCCCCc1ccc(OCC(=O)Cn2ccc3cc(C(=O)OC(C)(C)C)ccc32)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(=O)C(F)(F)F)c3cc(C(=O)O)ccc32)cc1,,ClCCl,,,,test
US05455273,C#CCN(C(=O)c1ccc(Cl)cc1)[C@@H]1CC[C@@H](c2ccc(CNC)cc2)CC1.OCCCBr>>C#CCN(C(=O)c1ccc(Cl)cc1)[C@@H]1CC[C@@H](c2ccc(CCCO)cc2CNC)CC1,,CO,ClCCl,,,test
US06218430B1,CC(=O)C(C)(C)C.CCC(CC)(c1ccc(O)c(C)c1)c1ccc(OCC(O)C(C)(C)C)c(C)c1>>CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc(OCC(O)C(C)(C)C)c(C)c1,,CN(C)C=O,,CCOC(C)=O,[H-].[Na+],test
US20120270865A2,CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3ccc(N)cc3c2C)C2CCCCC2)cc1.O=Cc1ccccc1>>CCOC(=O)CCN(C)C(=O)c1ccc(NC(c2oc3ccc(NCc4ccccc4)cc3c2C)C2CCCCC2)cc1,,CC(=O)O,CCO,[BH3-]C#N.[Na+],,test
US04501908,CCC(C(=O)OC(=O)C(CC)c1ccccc1)c1ccccc1>>CCC(C(=O)O)c1ccccc1,,CCOCC,,c1ccncc1,,test
US05283251,CC(C)Cc1ccc(C(Br)c2ccc(CC(C)C)cc2)cc1.Nc1cccc(C(=O)n2cc(CCCC(=O)O)c3cc(Cl)ccc32)c1>>CC(C)Cc1ccc(C(Nc2cccc(C(=O)n3cc(CCCC(=O)O)c4cc(Cl)ccc43)c2)c2ccc(CC(C)C)cc2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20100010057A1,CC(=O)C(Br)c1ccc(Cl)c(S(C)(=O)=O)c1.NC(N)=S>>Cc1nc(N)sc1-c1ccc(Cl)c(S(C)(=O)=O)c1,,CCO,,,,test
US05505931,C[C@H](NC(=O)OC(C)(C)C)C(=O)O.Nc1ccc(CCC(C(=O)O)N2CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC2)cc1>>C[C@H](N)C(=O)O.Nc1ccc(CCC(C(=O)O)N2CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC2)cc1,,O=C(O)C(F)(F)F,,,,test
US20110275797A1,COC(=O)c1ccc(-c2ccccc2)cc1NC(=O)c1cc(-c2ccco2)ccc1OC(C)=O>>O=C(Nc1cc(-c2ccccc2)ccc1C(=O)O)c1cc(-c2ccco2)ccc1O,,C1COCCO1,,Cl,[Na+].[OH-],test
US20110224193A1,CCOC(=O)c1nnc2n1CCN(c1ccc(N)cn1)C2.NC1CCCC1>>Nc1ccc(N2CCn3c(nnc3C(=O)NC3CCCC3)C2)nc1,,CCCCCC,CCOCC,,,test
US20150305334A1,C1CCOC1.CC1CCCC(C)(C)C1=O>>C#CC1(O)C(C)CCCC1(C)C,,O,,[Li],,test
US20040082619A1,CO.Cc1ccc(O)c(Cl)n1>>COc1nc(C)ccc1O,,CC(=O)O,,O,C[O-].[Na+],test
US20130296371A1,CC(C)C(=O)O[C@H]1[C@H](C)OC(=O)[C@@H](NC(=O)OC(C)(C)C)COC(=O)[C@@H]1CCO.O=C(Cl)c1ccccc1>>CC(C)C(=O)O[C@H]1[C@H](C)OC(=O)[C@@H](NC(=O)OC(C)(C)C)COC(=O)[C@@H]1CCOC(=O)c1ccccc1,,ClCCl,c1ccncc1,,,test
US04665171,CCOC(=O)CBr.O=C1N[C@@H](c2ccccc2)CO1>>O=C(O)CN1C(=O)OC[C@@H]1c1ccccc1,,C1CCOC1,,[Na+].[OH-],,test
US20090118501A1,C1CCOC1.CCOC(=O)CSc1cnc(N)s1.CC[C@@H]1CC[C@@H](NC2CCCC2)CC1>>CCOC(=O)CSc1cnc(NC(=O)N(C2CCCC2)[C@@H]2CC[C@@H](CC)CC2)s1,CN(C)c1ccncc1,,,,,test
US20040254215A1,CCCCOC(=O)c1nc(O)c2ccccc2c1OCc1ccccc1.ClCCl>>CCCCOC(=O)c1nc(OC)c2ccccc2c1OCc1ccccc1,,O,,,,test
US20150266881A1,COC(=O)c1ccc([C@@H]2C[C@H]2NC(=O)OC(C)(C)C)cc1.Cl>>COC(=O)c1ccc([C@@H]2C[C@H]2N)cc1.Cl,,C1CCOC1,CO,CCOC(C)=O,,test
US04267176,C=C(Cl)C#N.CCOC(=O)C(=N)N>>CCOC(=O)c1nccc(N)n1,,CCO,,Br,CCN(CC)CC,test
US05278152,CCOP(=O)(Cc1ccccc1C=O)OCC.NNC(N)=S>>CCOP(=O)(Cc1ccccc1C=NNC(N)=S)OCC,,CCO,,CC(=O)O,,test
US20090099231A1,CC(N)Cc1cccc([N+](=O)[O-])c1.CS(=O)(=O)Cl>>CC(Cc1cccc([N+](=O)[O-])c1)NS(C)(=O)=O,,ClCCl,,CCN(CC)CC,Cl,test
US20060293319A1,COC(=O)c1ccc(N=C=O)cc1.O=C1Nc2cc(Cl)ccc2C1(Cc1cccc(Cl)c1)C1CCCNC1>>COC(=O)c1ccc(NC(=O)N2CCCC(C3(Cc4cccc(Cl)c4)C(=O)Nc4cc(Cl)ccc43)C2)cc1,,ClCCl,,CCN(CC)CC,,test
US20080139505A1,CC(=O)c1ccc(O)c(Cl)c1O.N#Cc1cccc(C(OC2CCCCO2)c2ccc(CO)cc2)c1>>CC(=O)c1ccc(OCc2ccc(C(OC3CCCCO3)c3cccc(C#N)c3)cc2)c(Cl)c1O,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140206681A1,COc1ccc(CNc2nccn3c([C@@H]4CC[C@@H]5COC(=O)N5C4)nc(-c4ccc(C(=O)Nc5cc(C(F)(F)F)ccn5)cc4)c23)c(OC)c1>>Nc1nccn2c([C@@H]3CC[C@@H]4COC(=O)N4C3)nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)ccn4)cc3)c12,,O=C(O)C(F)(F)F,,,,test
US20160122344A1,COCCOc1cc(CC(N)CSC)ccc1Cl.O=CO>>COCCOc1cc(CC(CSC)NC=O)ccc1Cl,,C1COCCO1,,,,test
US20120046266A1,BrCc1ccccc1.COCCOCOc1cc(O)c(C(C)=O)c(OCOCCOC)c1>>COCCOCOc1cc(OCOCCOC)c(C(C)=O)c(OCc2ccccc2)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20030153580A1,CC(C)I.N#Cc1ccccc1O>>CC(C)Oc1ccccc1C#N,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100179150A1,CN.Cc1ccc(S(=O)(=O)OC[C@@H]2CN(C(=O)OC(C)(C)C)CC[C@@H]2NC(=O)c2[nH]c(C)c(Cl)c2Cl)cc1>>CNC[C@@H]1CN(C(=O)OC(C)(C)C)CC[C@@H]1NC(=O)c1[nH]c(C)c(Cl)c1Cl,,C1CCOC1,CCOC(C)=O,,,test
US04207327,CN1CC(N)CN1C.COc1cc(C(=O)Cl)cc(OC)c1OC>>COc1cc(C(=O)NC2CN(C)N(C)C2)cc(OC)c1OC,,ClC(Cl)Cl,,,,test
US20100190764A1,COC(=O)CC1CCN(C2CCC3(Cc4ccccc4Cc4ccccc43)C2)CC1>>O=C(O)CC1CCN(C2CCC3(Cc4ccccc4Cc4ccccc43)C2)CC1,,CO,O,[K+].[OH-],,test
US20090247500A1,COc1ccc(Cl)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@@H]1CCCN1C(=O)OC(C)(C)C>>COc1ccc(Cl)cc1C(=O)/N=c1\sc(C(C)(C)C)cn1C[C@@H]1CCCN1,,CO,,C1COCCO1,Cl,test
US20160000760A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COc1cc(Br)ccc1S(=O)(=O)NC1(C#N)CC1>>COc1ccc(B2OC(C)(C)C(C)(C)O2)cc1S(=O)(=O)NC1(C#N)CC1,,C1COCCO1,,ClCCl,CC(=O)[O-].[K+],test
US20090318486A1,COC(=O)CC#N.O=C1Nc2ccc(Cl)cc2C1=O>>COC(=O)/C(C#N)=C1\C(=O)Nc2ccc(Cl)cc21,,CO,,C1CCNCC1,,test
US20090270355A1,CCCCc1cc(O[C@@H]2CCN(C(=O)OC(C)(C)C)C2)c2ncccc2c1>>CCCCc1cc(O[C@@H]2CCNC2)c2ncccc2c1,,C1COCCO1,,Cl,,test
US20140179743A1,CCOc1ccc(/C=C2\SC(=O)N(CCN)C2=O)cc1.N#Cc1ccc(C(=O)O)cc1>>CCOc1ccc(/C=C2\SC(=O)N(CCNC(=O)c3ccc(C#N)cc3)C2=O)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160046618A1,C[C@]1(c2cc([N+](=O)[O-])cc(F)c2F)N=C(N)S[C@@H]2[C@H]1C2(F)F>>C[C@]1(c2cc(N)cc(F)c2F)N=C(N)S[C@@H]2[C@H]1C2(F)F,[Zn],CC(=O)O,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US03989707,CC#CBr.CCOC(=O)N1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1>>C#CCn1c(=O)n(C2CCN(C(=O)OCC)CC2)c2ccc(Cl)cc21,,CN(C)P(=O)(N(C)C)N(C)C,,[H-].[Na+],,test
US04087421,C1CNCCN1.CSC1=Nc2ccccc2N(C)c2cscc21.O=C(O)/C=C/C(=O)O>>CN1c2ccccc2N=C(N2CCNCC2)c2cscc21.O=C(O)/C=C/C(=O)O,CC(=O)O,CCO,,Cc1ccccc1C,,test
US20050267095A1,NCC1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1.O=S(=O)(Cl)Cc1ccccc1>>O=S(=O)(Cc1ccccc1)NCC1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1,,ClCCl,,CCN(CC)CC,,test
US05866560,C[C@]12C[C@H](F)[C@@H]3c4ccc(OC5CCCCO5)cc4C[C@@H](CCCCCO)[C@H]3[C@@H]1CCC2=O.Cc1ccc(S(=O)(=O)OS(=O)(=O)c2ccc(C)cc2)cc1>>Cc1ccc(S(=O)(=O)OCCCCC[C@@H]2Cc3cc(OC4CCCCO4)ccc3[C@H]3[C@@H](F)C[C@]4(C)C(=O)CC[C@H]4[C@H]23)cc1,,CCOC(C)=O,c1ccncc1,,,test
US06020363,COc1cc(O)c2c(=O)oc(CCl)cc2c1.[C-]#N>>COc1cc(O)c2c(=O)oc(CC#N)cc2c1,,CS(C)=O,,O,,test
US06313153B1,NCCc1ccccc1O.O=C(O)/C=C/c1cccnc1>>O=C(/C=C/c1cccnc1)NCCc1ccccc1O,,CN(C)C=O,,Br,O=C([O-])[O-].[K+].[K+],test
US20030109539A1,BrCc1ccccc1Br.C=CC[Mg]Br>>C=CCCc1ccccc1Br,,C1CCOC1,,,,test
US20030055265A1,COc1ccc(-c2nc(CCCO)c(C)o2)cc1.O=Cc1ccc(O)c2ccccc12>>COc1ccc(-c2nc(CCCOc3ccc(C=O)c4ccccc34)c(C)o2)cc1,,Cc1ccccc1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030149266A1,Clc1ncc(Br)c(Nc2ccccc2)n1.Nc1ccc(CC(=O)O)cc1>>O=C(O)Cc1ccc(Nc2ncc(Br)c(Nc3ccccc3)n2)cc1,,CCCCO,,Cl,[Na+].[OH-],test
US06414005B1,BrC(Br)(Br)Br.O=[N+]([O-])c1ccc(-n2cccc2)c(CO)c1>>O=[N+]([O-])c1ccc(-n2cccc2)c(CBr)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US07109243B2,COc1ccc(NCCNC(=O)[C@H](Cc2ccc(OC(C)(C)C)cc2)NC(=O)c2cccc(C)c2)cc1>>COc1ccc(NCCNC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)c2cccc(C)c2)cc1,,ClCCl,,,,test
US20090156607A1,CC(C)(C)OC(=O)n1nc(CBr)c2cc(Br)cnc21.O=C1CC(C=C(F)F)CN1>>O=C1CC(C=C(F)F)CN1Cc1n[nH]c2ncc(Br)cc12,,CN(C)C=O,O,[H-].[Na+],,test
US20150087639A1,CCCCCCN(CCCCCC)c1ccc(NC(=O)CC(C)=O)cc1Br.N>>CCCCCCN(CCCCCC)c1ccc(NC(=O)/C=C(/C)N)cc1Br,,CO,,,,test
US20040162303A1,COc1ccc(F)cc1C(=O)c1cnc(N[C@@H]2CC[C@@H](NC(=O)OC(C)(C)C)CC2)nc1N>>COc1ccc(F)cc1C(=O)c1cnc(N[C@@H]2CC[C@@H](N)CC2)nc1N,,ClCCl,O=C(O)C(F)(F)F,,,test
US20140100168A1,O=C(O)c1ccc(F)c(S(=O)(=O)Cl)c1.O=S(Cl)Cl>>O=C(Cl)c1ccc(F)c(S(=O)(=O)Cl)c1,CN(C)C=O,,,,,test
US06200999B1,CCOC(=O)c1onc(OCC)c1C.O=C1CCC(=O)N1Br>>CCOC(=O)c1onc(OCC)c1CBr,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US06277851B1,CCOC(C)=O.N#Cc1ccccc1O>>CC(=O)OCCOc1ccccc1C#N,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090111791A1,CC(C)(C)OC(=O)N1CCC(N)C1=O.Clc1ncccn1>>CC(C)(C)OC(=O)N1CCC(Nc2ncccn2)C1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20120172333A1,CCOC(=O)c1c(N)cc(Cl)n1-c1ccc(CC)cc1.O=C(Cl)Cc1ccccc1>>CCOC(=O)c1c(NC(=O)Cc2ccccc2)cc(Cl)n1-c1ccc(CC)cc1,,ClCCl,,c1ccncc1,,test
US20150218181A1,Cn1ncc(B2OC(C)(C)C(C)(C)O2)c1C=O>>Cn1ncc(B2OC(C)(C)C(C)(C)O2)c1CO,,CO,,[BH4-].[Na+],,test
US06187802B1,Br.O=C(CSC1=NCCN1)C1(c2ccc(Cl)cc2)CCC1>>Br.Clc1ccc(C2(C3=CSC4=NCCN34)CCC2)cc1,,CC(=O)O,,,,test
US20090149448A1,CC[C@H]1CN(Cc2ccccc2)CCN1C(=O)OC(C)(C)C>>CC[C@H]1CNCCN1C(=O)OC(C)(C)C,[Pd],CCO,,,,test
US04208514,CC(C)N1C(=O)c2ccccc2NS1(=O)=O.CS(=O)(=O)Cl>>CC(C)N1C(=O)c2ccccc2N(S(C)(=O)=O)S1(=O)=O,,CC#N,,CC(C)(C)[O-].[K+],,test
US20100121048A1,Cc1cc(C(=O)N2CCN(Cc3ccccc3)C[C@@H]2CO)c(-c2ccccc2)n1-c1ccccc1>>Cc1cc(C(=O)N2CCN(Cc3ccccc3)C[C@@H]2C=O)c(-c2ccccc2)n1-c1ccccc1,,CS(C)=O,ClCCl,CCN(CC)CC,O=C([O-])O.[Na+],test
US04732979,O=C1CCC2=C(CCc3c(Cl)cccc32)N1>>Clc1cccc2c1CCC1=C2CCCN1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20120264823A1,C=CCOc1ccc([C@@H]2C[C@H]2C(=O)OCC)cc1>>C=CCOc1ccc([C@@H]2C[C@H]2C(=O)O)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20100179161A1,Cc1cc(=O)n(-c2ccc(Cl)nn2)[nH]1.OCc1ccc(OC(F)(F)F)cc1>>Cc1cc(=O)n(-c2ccc(OCc3ccc(OC(F)(F)F)cc3)nn2)[nH]1,,C1CCOC1,O,CC(C)(C)[O-].[K+],,test
US20100240658A1,CC(=O)Cl.CC1CCCCN1c1ccc(C(=O)O)cc1N>>CC(=O)Nc1cc(C(=O)O)ccc1N1CCCCC1C,,ClCCl,,c1ccncc1,,test
US20140309225A1,CC(=O)N1CCC(N)C(NC(=O)OC(C)(C)C)C1.N#Cc1cc(F)c(Cl)nc1Cl>>CC(=O)N1CCC(Nc2nc(Cl)c(C#N)cc2F)C(NC(=O)OC(C)(C)C)C1,,CCOC(C)=O,,CCN(CC)CC,CS(C)=O,test
US20110230539A1,CCC(=O)N[C@H](C[C@H](C)C(Cl)(Cl)Cl)C(=O)N1C(=O)C=C(OC)[C@@H]1C[C@H](C)C(Cl)(Cl)Cl.CCOC(C)=O.CO.C[C@@H](C[C@H]1C(=O)N(C)[C@@H](C[C@H](C)C(Cl)(Cl)Cl)C(=O)N1C)C(Cl)Cl>>CCC(=O)N[C@H](C[C@H](C)C(Cl)(Cl)Cl)C(=O)N1C(=O)C=C(OC)[C@@H]1C[C@H](C)CCl.CCC(=O)N[C@H](C[C@H](C)C(Cl)Cl)C(=O)N1C(=O)C=C(OC)[C@@H]1C[C@H](C)C(Cl)Cl,,CO,,,,test
US20130034504A1,CC(C)(C)OC(=O)N1CCC(COC(=O)C(O)(c2ccccc2)C2CCCCC2)CC1.Cl>>Cl.O=C(OCC1CCNCC1)C(O)(c1ccccc1)C1CCCCC1,,ClCCl,,,,test
US06306873B1,CC(C)(C)OC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=CCCCCc1ccccc1>>CC(C)(C)OC(=O)/C=C/CCCCc1ccccc1,,C1CCOC1,,,,test
US06479519B1,COC(=O)C[C@@H](N)c1ccc(NC(=O)OC(C)(C)C)cc1.COCCOCC(=O)O>>COCCOCC(=O)N[C@H](CC(=O)OC)c1ccc(N)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070155805A1,CCOC(=O)COc1ccc(O)cc1C.COCCC(CCBr)c1sc2cc(C(F)(F)F)ccc2c1C>>CCOC(=O)COc1ccc(OCCC(CCOC)c2sc3cc(C(F)(F)F)ccc3c2C)cc1C,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090270412A1,CC(=CBr)c1ccc(F)c(F)c1.CC1c2[nH]c3ccc(Cl)cc3c2CCN1C>>CC(=Cn1c2c(c3cc(Cl)ccc31)CCN(C)C2C)c1ccc(F)c(F)c1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20040127574A1,CCOC(=O)C(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccncc1>>O=C(O)C(Cc1ccc(C(F)(F)F)cc1)C(O)c1ccncc1,,CO,,Cl,[Na+].[OH-],test
US20130034504A1,CC(C)(C)[Si](C)(C)O[C@@H](CN)c1ccc(O)c2[nH]c(=O)ccc12.Cl>>Cl.NC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12,,CO,,O=CO,,test
US20060135552A1,CC(=O)CC(=O)C(F)(F)F.Nc1sc(Cl)cc1C(=O)c1ccc(F)cc1>>Cc1nc2sc(Cl)cc2c(-c2ccc(F)cc2)c1C(=O)C(F)(F)F,O=S(=O)(O)O,CC(=O)O,,,,test
US04891432,CCOC(=O)C(C)(C)CCCCOc1cccc(OCCCCCn2ccnc2)c1>>CC(C)(CCCCOc1cccc(OCCCCCn2ccnc2)c1)C(=O)O,,CCO,,[Na+].[OH-],,test
US20090137561A1,C=CC(C)(C)C(O)c1cc(C(=O)OC)ccc1-c1cc(OC)ccc1F.CI>>C=CC(C)(C)C(OC)c1cc(C(=O)OC)ccc1-c1cc(OC)ccc1F,,CN(C)C=O,,O,[H-].[Na+],test
US20070010670A1,Cc1cccc2c1NCCO2.O=C(Cl)c1cc(Cl)c(O)c(Cl)c1>>Cc1cccc2c1N(C(=O)c1cc(Cl)c(O)c(Cl)c1)CCO2,,CCOC(C)=O,,,,test
US20110112111A1,BrC(Br)(Br)Br.O=Cc1ccc(CN2CCCC2)cc1Cl>>Clc1cc(CN2CCCC2)ccc1C=C(Br)Br,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20080132481A1,CCNCC.O=C(Cl)OCCl>>CCN(CC)C(=O)OCCl,,CCCCCCC,,,,test
US20020165264A1,CCOc1c(OCC)c(=O)c1=O.Nc1ccccn1>>CCOc1c(Nc2ccccn2)c(=O)c1=O,,CCO,,,,test
US20150315182A1,O=[N+]([O-])c1ccc(F)cc1Nc1nc(Cl)cc(Cl)n1>>Nc1ccc(F)cc1Nc1nc(Cl)cc(Cl)n1,[Pd],CCOC(C)=O,,,,test
US04030925,Nc1ccc(NNC(=O)C(F)(F)F)cc1.S=C=Nc1ccccc1>>O=C(NNc1ccc(NC(=S)Nc2ccccc2)cc1)C(F)(F)F,,CCO,,,,test
US20060111353A1,BrCCC1CCCC1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>[Br-].c1ccc([P+](CCC2CCCC2)(c2ccccc2)c2ccccc2)cc1,,Cc1ccccc1,,,,test
US20140121198A1,N#CCC1(O)CCC(Nc2c([N+](=O)[O-])cnc3ccsc23)CC1>>N#CCC1(O)CCC(Nc2c(N)cnc3ccsc23)CC1,[Pd],CO,,,,test
US20160168156A1,CCO/C=C/C(=O)OCC.CCOC(=O)c1cn[nH]c1N>>CCOC(=O)c1cnn2ccc(=O)[nH]c12,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20040265717A1,CCN(CC)c1ccc2c(c1)C(=O)c1cc(N(CC)CC)ccc1-2.NN>>CCN(CC)c1ccc2c(c1)C(=NN)c1cc(N(CC)CC)ccc1-2,Cl,CC(C)O,,O,,test
US04900653,CCCCCCS(=O)(=O)Cl.Cc1nc2cc(N)ccc2o1>>CCCCCCS(=O)(=O)Nc1ccc2oc(C)nc2c1,,c1ccncc1,,O,,test
US20060030609A1,COC(=O)[C@H]1CN(c2ccc3c(c2)CC(=O)N3C2CC2)C(=O)O1.N>>NC(=O)[C@H]1CN(c2ccc3c(c2)CC(=O)N3C2CC2)C(=O)O1,,CO,,,,test
US20060046980A1,COc1ccc(Oc2c(I)cc(OC(=O)c3ccccc3)cc2I)cc1C(C)C>>COc1ccc(Oc2c(I)cc(O)cc2I)cc1C(C)C,,CO,O,Cl,[Na+].[OH-],test
US20050090491A1,Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)Cl)cc3)c2)o1.NCC1CC1>>Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)NCC4CC4)cc3)c2)o1,,ClCCl,,,,test
US20160221945A1,CC(C)(C)OC(=O)N1CC[C@H](F)[C@H]1C(=O)NCc1ccc(F)c(-c2cnc(C(F)(F)F)cn2)c1.Cl>>Cl.O=C(NCc1ccc(F)c(-c2cnc(C(F)(F)F)cn2)c1)[C@H]1NCC[C@@H]1F,,C1COCCO1,,,,test
US07034045B1,CCCS(=O)(=O)Cl.COc1ccc(C(C)(O)CN)cc1>>COc1ccc(C(C)(O)CNS(=O)(=O)C(C)C)cc1,,C1CCOC1,,C1CCC2=NCCCN2CC1,,test
US20070167443A1,CON(C)C(=O)c1cn(Cc2cccc(Br)n2)c2ccccc2c1=O.COc1ccc([Mg]Br)cc1F>>COc1ccc(C(=O)c2cn(Cc3cccc(Br)n3)c3ccccc3c2=O)cc1F,,C1CCOC1,,,,test
US06147075,CCOc1cc2c(c(OC(C)=O)c1OCC)=NC(=O)C(=O)N=2>>COc1cc2c(c(O)c1OC)=NC(=O)C(=O)N=2,,O,,Cl,[Na+].[OH-],test
US06440975B1,COc1ccc([N+](=O)[O-])c(Cl)n1.NC(C(=O)O)C(c1ccccc1)c1ccccc1>>COc1ccc([N+](=O)[O-])c(NC(C(=O)O)C(c2ccccc2)c2ccccc2)n1,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20090186886A1,C1COCCN1.O=CCCc1nc2cc3c(cc2[n+]([O-])n1)CCO3>>[O-][n+]1nc(CCCN2CCOCC2)nc2cc3c(cc21)CCO3,,CN(C)C=O,CO,CC(=O)O,[BH3-]C#N.[Na+],test
US20080146607A1,CC(C)[Si](C(C)C)(C(C)C)n1ccc2cc(C(=O)C3(Cc4ccccc4)CCN(C(=O)OC(C)(C)C)C3)ccc21>>CC(C)(C)OC(=O)N1CCC(Cc2ccccc2)(C(=O)c2ccc3[nH]ccc3c2)C1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06184225B2,COc1cc2c(Oc3ccccc3)ncnc2cc1O.CSCCCl>>COc1cc2c(Oc3ccccc3)ncnc2cc1OCCSC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040010037A1,C[C@H]1CN[C@H](C)CN1.N#Cc1ccc(F)cc1C(F)(F)F>>C[C@H]1CN[C@H](C)CN1c1ccc(C#N)c(C(F)(F)F)c1,,CN(C)C=O,,O,,test
US06066641,O=c1[nH]c(=O)n(Cc2ccc(Cl)cc2)c2nc[nH]c12.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>O=c1[nH]c(=S)c2[nH]cnc2n1Cc1ccc(Cl)cc1,,c1ccncc1,,[Na+].[OH-],,test
US20040038943A1,COc1ccc(-c2nc3cc(Cl)c(Cl)cc3[nH]2)cc1[N+](=O)[O-].O=C(Cl)OCc1ccccc1>>COc1ccc(-c2nc3cc(Cl)c(Cl)cc3n2C(=O)OCc2ccccc2)cc1[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],,test
US20090312306A1,COC(=O)Cc1ccc(OC)nc1CCNCc1ccccc1>>COc1ccc2c(n1)CCN(Cc1ccccc1)C(=O)C2,,CCOC(C)=O,CN(C)C=O,,,test
US20110201611A1,O=C(Cc1ccc(-c2ccc(OCCN3CCOCC3)cc2)cn1)NCc1ccccc1>>N#CCc1ccc(-c2ccc(OCCN3CCOCC3)cc2)cn1,,CC#N,,C1COCCN1,,test
US20080312226A1,Cc1noc(NC(=O)OCC(Cl)(Cl)Cl)c1C.Clc1ccc(-c2csc(N3CCNCC3)n2)c(Cl)c1>>Cc1noc(NC(=O)N2CCN(c3nc(-c4ccc(Cl)cc4Cl)cs3)CC2)c1C,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20120149691A1,N#Cc1cnn2cc([N+](=O)[O-])cc2c1Nc1ccccc1.OO>>NC(=O)c1cnn2cc([N+](=O)[O-])cc2c1Nc1ccccc1,,CCO,,[NH4+].[OH-],,test
US20150038528A1,CC(C)(C)OC(=O)C[C@H](Cc1ccccc1)NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O>>N#Cc1nc(C(=O)N[C@H](CC(=O)O)Cc2ccccc2)c(O)c2ccc(Oc3ccccc3)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150080362A1,CCc1c(O)c(C(=O)OC)c(=O)n(Cc2ccc(OC)cc2OC)c1-c1ccc(C2CCN(C(=O)OC(C)(C)C)CC2)cc1>>CCc1c(-c2ccc(C3CCN(C)CC3)cc2)[nH]c(=O)c(C(=O)O)c1O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120149684A1,C=CCOCCC(=C)B1OC(C)(C)C(C)(C)O1>>CC1(C)OB(C2=CCOCC2)OC1(C)C,Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)(=Cc2ccccc2)[P](C2CCCCC2)(C2CCCCC2)C2CCCCC2)c(C)c1,ClCCl,,,,test
US20090286807A1,CC[C@H](C[C@H](O)[C@@H](N)CN1CC(=O)N(c2ccccc2Cl)CC1(C)C)C(=O)NCC(C)C.CC[C@H](C[C@H](O)[C@H](CN1CC(=O)N(c2ccccc2Cl)CC1(C)C)NC(=O)OC(C)(C)C)C(=O)NCC(C)C.O=C(O)/C=C/C(=O)O>>CC[C@H](C[C@H](O)[C@@H](N)CN1CC(=O)N(c2ccccc2Cl)CC1(C)C)C(=O)NCC(C)(C)C.CC[C@H](C[C@H](O)[C@@H](N)CN1CC(=O)N(c2ccccc2Cl)CC1(C)C)C(=O)NCC(C)(C)C.O=C(O)/C=C/C(=O)O,,CO,ClCCl,O=C(O)C(F)(F)F,,test
US20150225412A1,COC(=O)c1ccc2c(c1)nc(NC(=O)c1ccc(C(F)F)s1)n2C[C@H]1CCCN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CCC[C@@H]1Cn1c(NC(=O)c2ccc(C(F)F)s2)nc2cc(CO)ccc21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US06303593B1,C[C@H](C(=O)O)c1ccccc1.OC(Cc1ccccc1)CC1CCN(Cc2ccccc2)CC1>>C[C@H](C(=O)OC(Cc1ccccc1)CC1CCN(Cc2ccccc2)CC1)c1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US04584385,CC(=O)c1c[nH]c2ccccc12.O=C(Cl)OCc1ccccc1>>CC(=O)c1cn(C(=O)OCc2ccccc2)c2ccccc12,,C1CCOC1,,[H-].[Na+],,test
US20080009530A1,CCCCCS(N)(=O)=O.CCCS(=O)(=O)Oc1ccc(CO)c(Oc2ncc(C(F)(F)F)cc2Cl)c1.CN(C)C=O>>CCCCCS(=O)(=O)NC(=O)OCc1ccc(OS(=O)(=O)CCC)cc1Oc1ncc(C(F)(F)F)cc1Cl,,CCOC(C)=O,,C1CCC2=NCCCN2CC1,Cl,test
US03943141,Cc1ccc2c(=O)c(C(=O)O)cn(C(C)C)c2n1.Nc1nnn[nH]1>>Cc1ccc2c(=O)c(C(=O)Nc3nnn[nH]3)cn(C(C)C)c2n1,,CN(C)C=O,,CCN(CC)CC,CCOC(=O)Cl,test
US06130237,COc1ccc(COC(=O)c2ccc3ccccc3c2O)cc1.O=[N+]([O-])O>>COc1ccc(COC(=O)c2cc([N+](=O)[O-])c3ccccc3c2O)cc1,,CC(=O)O,,,,test
US05304644,COC(=O)c1ccc(Cl)c([N+](=O)[O-])c1.O=Cc1ccccc1O>>COC(=O)c1ccc(Oc2ccccc2C=O)c([N+](=O)[O-])c1,,CN(C)C=O,,[H-].[Na+],,test
US06627651B1,CCCOc1ccccc1CCCOS(C)(=O)=O.COC(=O)C1=Cc2cc(O)ccc2S(=O)(=O)CC1>>CCCOc1ccccc1CCCOc1ccc2c(c1)C=C(C(=O)OC)CCS2(=O)=O,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US05073556,CCOC(=O)C(=CNC1CC1)C(=O)c1c(F)c(OC(F)F)c(F)c(F)c1[N+](=O)[O-]>>CCOC(=O)c1cn(C2CC2)c2c(OC(F)F)c(F)c(F)c([N+](=O)[O-])c2c1=O,,C1CCOC1,,Cl,[H-].[Na+],test
US20030171303A1,N#CCCOC(=O)CC1(CNC(=O)OC(C(=O)c2ccccc2)c2ccccc2)CCCCC1.O=C(OO)c1cccc(Cl)c1>>N#CCCOC(=O)CC1(CNC(=O)OC(OC(=O)c2ccccc2)c2ccccc2)CCCCC1,,ClCCl,,O=C([O-])[O-].[Na+].[Na+],,test
US20010039344A1,CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1[N+](=O)[O-]>>CS(=O)(=O)c1ccc(C(CC2CCCC2)C(=O)Nc2nccs2)cc1NO,[Pd],CO,,[H][H],,test
US20120316161A1,CCCC(C(=O)OCC)c1c(C)nc2nc(C)n(C)c2c1-c1ccc(C)cc1>>CCCC(C(=O)O)c1c(C)nc2nc(C)n(C)c2c1-c1ccc(C)cc1,,CCO,CO,[Na+].[OH-],,test
US20150329538A1,CCOC(=O)C(=O)CC(=O)c1cccc2nc(C)c(NC(C)(C)C)nc12.NN>>CCOC(=O)c1cc(-c2cccc3nc(C)c(NC(C)(C)C)nc23)[nH]n1,,CC(=O)O,,,,test
US20050234074A1,CCCC[Sn](CCCC)(CCCC)c1nccs1.Oc1ccc2c(c1)COc1c-2cc2ccc(O)cc2c1Br>>CCCCc1c2c(cc3ccc(O)cc13)-c1ccc(O)cc1CO2,,CN(C)C=O,,,,test
US20120149676A1,CNCc1ccc(F)cc1.CNc1cc(Cl)c(C(=O)N[C@@H]2CC[C@@H](C(F)(F)F)CC2)cc1[N+](=O)[O-]>>CNc1cc(N(C)Cc2ccc(F)cc2)c(C(=O)N[C@@H]2CC[C@@H](C(F)(F)F)CC2)cc1[N+](=O)[O-],,O,,CC#N,,test
US20150259350A1,Cl.Cn1cc(-c2cnc3nnn(CC4CCCN(c5ncc(-c6ccn(C7CCN(C(=O)[O-])CC7)n6)cn5)C4)c3n2)cn1>>Cl.Cn1cc(-c2cnc3nnn(CC4CCCN(c5ncc(-c6ccn(C7CCNCC7)n6)cn5)C4)c3n2)cn1,,C1COCCO1,ClCCl,,,test
US20100184740A1,O=[N+]([O-])c1ccc(F)c(CBr)c1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>O=[N+]([O-])c1ccc(F)c(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c1.[Br-],,Cc1ccccc1,,,,test
US20130102611A1,CCOC(=O)CCCCCC=O.Cc1ccc(-c2nc3c(nc2-c2ccc(C)cc2)NCC=C3)cc1>>CCOC(=O)CCCCCCN1CC=Cc2nc(-c3ccc(C)cc3)c(-c3ccc(C)cc3)nc21,,ClCCCl,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070276011A1,COC(=O)c1cc(C=C2SC(=O)N(Cc3ccc(Cl)cc3Cl)C2=O)cc(OC)c1O>>COC(=O)c1cc(C=C2SC(=O)N(Cc3ccc(Cl)cc3Cl)C2=O)cc(O)c1O,,ClCCl,,BrB(Br)Br,O,test
US20060135554A1,CC(C)(C)OC(=O)NCCN.CCN(CC)C(=O)c1ccc(F)c([N+](=O)[O-])c1>>CCN(CC)C(=O)c1ccc(NCCNC(=O)OC(C)(C)C)c([N+](=O)[O-])c1,,CCO,,,,test
US20100129515A1,CCCCCCCCNC(=O)n1ccnc1.COc1cc(CN)ccc1O>>CCCCCCCCNC(=O)NCc1ccc(O)c(OC)c1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US05223511,O=C(Cl)OC(Cl)(Cl)Cl.O=c1[nH]c2ccccc2[nH]1>>O=C(Cl)n1c(=O)[nH]c2ccccc21,,C1CCOC1,,,,test
US20090270436A1,CC(C)(C)OC(=O)N1CCC2(CC1)CC(O)c1cc(C#N)ccc1O2.CC(C)(C)[Si](C)(C)Cl>>CC(C)(C)OC(=O)N1CCC2(CC1)CC(O[Si](C)(C)C(C)(C)C)c1cc(C#N)ccc1O2,,CN(C)C=O,,c1c[nH]cn1,,test
US06881589B1,C[C@@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)[C@H]4[C@H](O)C[C@]5(C)[C@@H](C6=CC(=O)OC6)CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)[C@H](O)[C@H](O)[C@H]1O>>C[C@@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)[C@H]4[C@H](O)C[C@]5(C)[C@@H](C6=CC(=O)OC6)CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)[C@H](O)[C@H](O)[C@H]1O,,O,,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20140275528A1,COC(=O)c1ccc(Cn2c(Oc3cccc(OC(F)(F)F)c3)nc3c2c(=O)n(C)c(=O)n3C)cc1>>Cn1c(=O)c2c(nc(Oc3cccc(OC(F)(F)F)c3)n2Cc2ccc(CO)cc2)n(C)c1=O,,COCCOC,,[BH4-].[Li+],,test
US05070087,COC(=O)Cl.NC(=O)C(c1ccc(F)cc1)(c1ccc(F)cc1)C1CCNCC1>>COC(=O)N1CCC(C(C(N)=O)(c2ccc(F)cc2)c2ccc(F)cc2)CC1,,ClCCl,,O=C([O-])O.[Na+],,test
US20100331335A1,COC(=O)CN1C(=O)CCc2cnccc21>>O=C(O)CN1C(=O)CCc2cnccc21,,CC(=O)O,,Cl,,test
US20060014708A1,CC(C)(C)OC(=O)N1CCC(Nc2ccc(C(=O)c3ccccc3F)c(N)n2)CC1>>Nc1nc(NC2CCNCC2)ccc1C(=O)c1ccccc1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090076282A1,Cc1cc(F)c(-n2nc(C(F)(F)F)nc2NC(=O)C(F)(F)F)cc1C(SC(c1cc(-n2nc(C(F)(F)F)nc2NC(=O)C(F)(F)F)c(F)cc1C)C(F)(F)F)C(F)(F)F.O=C(OO)c1cccc(Cl)c1>>Cc1cc(F)c(-n2nc(C(F)(F)F)nc2NC(=O)C(F)(F)F)cc1C(S(=O)C(c1cc(-n2nc(C(F)(F)F)nc2NC(=O)C(F)(F)F)c(F)cc1C)C(F)(F)F)C(F)(F)F,,ClC(Cl)Cl,,,,test
US20080306109A1,CCOC(=O)C=[N+]=[N-].Cc1cc2cc(Cl)ccn2c1>>CCOC(=O)Cc1c(C)cc2cc(Cl)ccn12,[Cu],Cc1ccccc1,,,,test
US04239898,Cc1ccc(Oc2cscc2C(=O)O)cc1N.Cl>>Cc1ccc(Oc2cscc2CO)cc1N.Cl,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20100105885A1,C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)C=O>>C[C@H](O)[C@H](O)[C@@H](O)[C@@H](O)CO,[Ni],,,,,test
US04229448,Cc1ccc(O)cn1.Clc1cccc(Br)c1>>Cc1ccc(Oc2cccc(Cl)c2)cn1,[Cu],CCO,CN(C)C=O,[K],,test
US20140073589A1,C[C@@H](O[C@H]1[C@H](OCc2ccccc2)C2COC(O2)[C@@H]1N=[N+]=[N-])C(=O)N[C@H](C)Cc1ccccc1>>C[C@@H](O[C@H]1[C@H](OCc2ccccc2)C2COC(O2)[C@@H]1N)C(=O)N[C@H](C)Cc1ccccc1,[Pd],CO,,,,test
US20090137557A1,O=c1cc(CN2CCCCC2)nc(-c2ccccc2OCc2ccccc2)n1CCc1ccccc1>>O=c1cc(CN2CCCCC2)nc(-c2ccccc2O)n1CCc1ccccc1,[Pd],CCO,,,,test
US20160237090A1,C[C@H]1Cn2ncc(N3CC(c4ccccn4)OC3=O)c2CN1.O=C(Nc1cc(F)c(F)c(F)c1)Oc1ccccc1>>C[C@H]1Cn2ncc(N3CC(c4ccccn4)OC3=O)c2CN1C(=O)Nc1cc(F)c(F)c(F)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20150299189A1,O=c1sc2cc([N+](=O)[O-])ccc2n1Cc1ccccc1>>Nc1ccc2c(c1)sc(=O)n2Cc1ccccc1,,O,,CCO,[Cl-].[NH4+],test
US05719141,C=CC(C[C@H](O)[C@H](CC(C)(C)CCO[Si](C(C)C)(C(C)C)C(C)C)NC(=O)OC(C)(C)C)C(C)C.COC(C)(C)OC>>C=CC(C[C@@H]1OC(C)(C)N(C(=O)OC(C)(C)C)[C@H]1CC(C)(C)CCO[Si](C(C)C)(C(C)C)C(C)C)C(C)C,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20130059846A1,Cc1ccc(-c2noc(C3CC(F)(F)C3)n2)cc1NC(=O)c1cnc2cc(C#C[Si](C)(C)C)ccn12>>C#Cc1ccn2c(C(=O)Nc3cc(-c4noc(C5CC(F)(F)C5)n4)ccc3C)cnc2c1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20110251176A1,Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2NC(=O)OC(C)(C)C)c1C1=CCN(C(=O)OC(C)(C)C)CC1>>Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1C1=CCNCC1,,C1COCCO1,CO,Cl,,test
US20160039819A1,BrP(Br)Br.C[C@@H](CO)Cn1ncc2ccccc21>>C[C@H](CBr)Cn1ncc2ccccc21,,Cc1ccccc1,,,,test
US20110183985A1,CON(C)C(=O)c1ccc2ccccc2c1Br.C[Mg]Br>>CC(=O)c1ccc2ccccc2c1Br,,C1CCOC1,,CCOCC,,test
US20100216814A1,CC(=CBr)c1ccncc1.CN1CCc2[nH]c3ccc(OC(F)(F)F)cc3c2C1>>C/C(=C\n1c2c(c3cc(OC(F)(F)F)ccc31)CN(C)CC2)c1ccncc1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20030166725A1,COc1cc(C(=O)c2cccc(C)c2)c(Oc2c(Br)cc(CC(=O)O)cc2Br)cc1C(C)C>>Cc1cccc(C(=O)c2cc(O)c(C(C)C)cc2Oc2c(Br)cc(CC(=O)O)cc2Br)c1,,ClCCl,,BrB(Br)Br,,test
US20140275028A1,NCc1ccc(Br)cc1.O=[N+]([O-])c1cc(OCc2ccc3ccccc3n2)ccc1F>>O=[N+]([O-])c1cc(OCc2ccc3ccccc3n2)ccc1NCc1ccc(Br)cc1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,Cl,test
US20040077646A1,CI.N#CCNC(=O)C1CCCCC1NC(=O)c1cc2ccc(Cl)cc2[nH]1>>Cn1c(C(=O)NC2CCCCC2C(=O)NCC#N)cc2ccc(Cl)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20030004304A1,CCOC(=O)CCCCCOS(C)(=O)=O.OCCOCCOCCOCCOCCOCCOCc1ccccc1>>CCOC(=O)CCCCCOCCOCCOCCOCCOCCOCCOCc1ccccc1,,Cc1ccccc1,,[H-].[Na+],,test
US04521597,CCOC(=N)OCC.O=S(=O)(Cl)c1ccccc1OC(F)F>>CCOC(=NS(=O)(=O)c1ccccc1OC(F)F)OCC,,CC(C)=O,,CCN(CC)CC,,test
US05798311,CC(=O)OC=O.CCCNC1CN(C(=O)Nc2ccc(C(F)(F)F)cc2)N=C1c1ccc(OCCC)cc1>>CCCOc1ccc(C2=NN(C(=O)Nc3ccc(C(F)(F)F)cc3)CC2N(C=O)CCC)cc1,,CCOC(C)=O,,c1ccncc1,,test
US20110237565A1,CC(C)(C)OC(=O)N1CCN(c2ncc(-c3cccs3)nc2C#N)CC1>>CC(C)(C)OC(=O)N1CCN(c2ncc(-c3cccs3)nc2CN)CC1,[Ni],CO,,N,,test
US20020193396A1,CC(C)(C)OC(=O)NCCOCCn1cnc2cnc3ccccc3c21.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)OC(=O)NCCOCCn1cnc2c[n+]([O-])c3ccccc3c21,,ClCCl,,O=C([O-])O.[Na+],,test
US20150158878A1,O=C(Nc1nc2cc3c(cc2[nH]1)OC(F)(F)O3)c1cc([N+](=O)[O-])c[nH]1>>Nc1c[nH]c(C(=O)Nc2nc3cc4c(cc3[nH]2)OC(F)(F)O4)c1,[Pd],CO,,,,test
US20100249124A1,COC(=O)c1ccc(-c2ccc(C(C)C(O)(c3ccc4oc(=O)n(C)c4c3)C(F)(F)F)c(Cl)c2)cc1F>>CC(c1ccc(-c2ccc(C(=O)O)c(F)c2)cc1Cl)C(O)(c1ccc2oc(=O)n(C)c2c1)C(F)(F)F,,C1CCOC1,,Cl,[Li+].[OH-],test
US20040132727A1,COc1cc2ncnc(Oc3ccc(N)c([N+](=O)[O-])c3)c2cc1OC.N[C@@H]1CCN(Cc2ccccc2)C1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1cc2ncnc(Oc3ccc(NC(=O)N[C@@H]4CCN(Cc5ccccc5)C4)c([N+](=O)[O-])c3)c2cc1OC,,CCN(CC)CC,ClC(Cl)Cl,O=C([O-])O.[Na+],,test
US05998433,C=O.CNC.O=C1c2ccccc2C(=O)c2cc(C(=O)N3CCc4occc4C3)ccc21>>CN(C)Cc1cc2c(o1)CCN(C(=O)c1ccc3c(c1)C(=O)c1ccccc1C3=O)C2,,CC(=O)O,,,,test
US20070244120A1,CC(C)(C)C(=O)CC#N.N#CCCNN>>CC(C)(C)c1cc(N)n(CCC#N)n1,,CCO,,,,test
US20120142677A1,CC(C)(C)c1cc(NC(=O)[C@@H]2C[C@@H](O)CN2)no1.Clc1ccnc(Cl)n1>>CC(C)(C)c1cc(NC(=O)[C@@H]2C[C@@H](O)CN2c2ccnc(Cl)n2)no1,,CCO,,CCN(C(C)C)C(C)C,Cl,test
US20090226398A1,CC(C)(C)OC(=O)Nc1nc(Cl)ccc1C=O>>CC(C)(C)OC(=O)Nc1nc(Cl)ccc1CO,,CO,,[BH4-].[Na+],,test
US20140323484A1,CCCO.COc1cc(Br)c(Cl)cc1[N+](=O)[O-]>>C=Cc1cc(OC)c([N+](=O)[O-])cc1Cl,,CCCO,,CCN(CC)CC,O,test
US20120101051A1,COS(=O)(=O)OC.N#Cc1cc(Br)c(O)cc1Cl>>COc1cc(Cl)c(C#N)cc1Br,,C1CCOC1,CCOC(C)=O,O,[Li+].[OH-],test
US20070054939A1,COC(=O)C(C)NCCC(=O)OC(C)(C)C>>CC(NCCC(=O)OC(C)(C)C)C(=O)O,,CO,O,[K+].[OH-],,test
US20070043036A1,CCOC(=O)c1cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n(-c2cccc(C(F)(F)F)c2)c1C>>Cc1c(C(=O)O)cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n1-c1cccc(C(F)(F)F)c1,,C1CCOC1,O,[Na+].[OH-],,test
US20040029950A1,NCCc1c[nH]c2ccccc12.O=[N+]([O-])c1ccc(F)c([N+](=O)[O-])c1>>O=[N+]([O-])c1ccc(NCCc2c[nH]c3ccccc23)c([N+](=O)[O-])c1,,CCO,O,O=C([O-])O.[Na+],,test
US20160129017A1,C[C@@]12CCC[C@H]1[C@@H]1CC[C@H]3C[C@H](I)CC[C@]3(C)[C@H]1CC2.[N-]=[N+]=[N-]>>C[C@@]12CCC[C@H]1[C@@H]1CC[C@H]3C[C@@H](N=[N+]=[N-])CC[C@]3(C)[C@H]1CC2,,CN(C)C=O,,O,,test
US20100048636A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC(CO)CC1CCCOC1>>CC(C)(C)OC(=O)N[C@H](CO)CC1CCCOC1,,ClCCl,,CCN(CC)CC,,test
US20040102484A1,COc1ccccc1CCC(=O)OCCS(=O)(=O)c1ccc(C)cc1.O=S(=O)(O)Cl>>COc1ccc(S(=O)(=O)Cl)cc1CCC(=O)OCCS(=O)(=O)c1ccc(C)cc1,,ClCCl,,,,test
US20050065178A1,CC(C)(C)OC(=O)N1C[C@@H]2CN(c3ccc(-c4ccccc4)nn3)C[C@@H]21.Cc1ccc(S(=O)(=O)O)cc1>>Cc1ccc(S(=O)(=O)O)cc1.c1ccc(-c2ccc(N3C[C@H]4CN[C@H]4C3)nn2)cc1,,CCOC(C)=O,,O,,test
US20090215758A1,NC(=S)N1CCSCC1.O=C(O)CCl>>O=C1CSC(N2CCSCC2)=N1,,c1ccncc1,,,,test
US20160200704A1,CC(C)(C)OC(=O)n1cc(Cl)c2cc(CO)ccc21.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)n1cc(Cl)c2cc(CCl)ccc21,,ClCCl,,CCN(CC)CC,,test
US20100234340A1,CCN(C(C)C)C(C)C.CCN=C=NCCCN(C)C.COc1cc(C)c(S(=O)(=O)N2CCc3ccc(CC(=O)O)cc32)c(C)c1.ClCCl.On1nnc2ccccc21>>COc1cc(C)c(S(=O)(=O)N2CCc3ccc(CC(=O)N4CCC5(CC4)CCN(c4ccncc4)CC5)cc32)c(C)c1,,ClCCl,,Cl,,test
US20140274933A1,CNc1ccc2nc(C)oc2c1.O=C(O)CBr>>Cc1nc2ccc(N(C)C(=O)CBr)cc2o1,CN(C)c1ccncc1,ClCCl,O,CCN=C=NCCCN(C)C,Cl,test
US20070185143A1,CC(=O)N1CCC(N(NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)CC1.Cl>>CC(=O)N1CCC(NN)CC1.Cl,,C1COCCO1,CO,,,test
US20150197509A1,CC1(C)OB(c2ccc(C(F)(F)F)cc2)OC1(C)C.N#Cc1cc(Br)ccc1F>>N#Cc1cc(-c2ccc(C(F)(F)F)cc2)ccc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040214868A1,COC(=O)c1ccc(NC(=O)c2cc(OCc3cc(C)on3)cc(OCc3ccccc3C)c2)nc1>>Cc1cc(COc2cc(OCc3ccccc3C)cc(C(=O)Nc3ccc(C(=O)O)cn3)c2)no1,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20110257171A1,CC(C)(C)OC(=O)N1CCC(n2cc(-c3ccc4nccn4c3)cn2)CC1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)N1CCC(n2cc(-c3ccc4ncc(Br)n4c3)cn2)CC1,,ClC(Cl)Cl,,,,test
US20100150831A1,COc1ccc2cccnc2c1N1CCCN(C(CC(=O)O)c2ccn(C(C)C)n2)CC1.NCCN1CCCC1>>COc1ccc2cccnc2c1N1CCCN(C(CC(=O)NCCN2CCCC2)c2ccn(C(C)C)n2)CC1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160222033A1,CCN(CC)S(F)(F)F.CCN(Cc1cc(=O)n2c(C(O)CCO[Si](C)(C)C(C)(C)C)c(C)sc2n1)c1ccc(F)cc1>>CCN(Cc1cc(=O)n2c(C(F)CCO[Si](C)(C)C(C)(C)C)c(C)sc2n1)c1ccc(F)cc1,,ClCCl,,,,test
US04233307,CN1C(=O)C2(CCN(Cc3ccccc3)CC2)c2ccccc21.O=C(Cl)OCc1ccccc1>>CN1C(=O)C2(CCN(C(=O)OCc3ccccc3)CC2)c2ccccc21,,O,,Cc1ccccc1,,test
US20060205737A1,COc1c(C)cc(F)cc1C(C)N.CS(=O)(=O)c1ccc(F)cc1F>>COc1c(C)cc(F)cc1C(C)Nc1cc(F)ccc1S(C)(=O)=O,,CN(C)C=O,,CCN(C(C)C)C(C)C,ClCCl,test
US20060142265A1,CC1(C)Oc2cc(Br)cnc2NC1=O>>CC1(C)CNc2ncc(Br)cc2O1,,C1CCOC1,,,,test
US20160096839A1,CC(=O)[Si](C)(C)C.COc1cc(-c2cc(Cl)ccc2Br)ncn1>>COc1cc(-c2cc(Cl)ccc2C(C)=O)ncn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US20020107253A1,Fc1ccccc1N1CCNCC1.O=CCCC1CC(c2cccc([N+](=O)[O-])c2)=NO1>>O=[N+]([O-])c1cccc(C2=NOC(CCCN3CCN(c4ccccc4F)CC3)C2)c1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US06395734B1,Cc1[nH]c(C=O)c(C)c1CCC(=O)O.O=C1Cc2ccc(O)cc2N1>>Cc1[nH]c(C=C2C(=O)Nc3cc(O)ccc32)c(C)c1CCC(=O)O,,CCO,,C1CCNCC1,,test
US05563158,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(S(=O)(=O)OCCCC2CCNCC2)cc1>>CC(C)(C)OC(=O)N1CCC(CCCO)CC1,,CC(C)(C)O,,[Na+].[OH-],,test
US20160039860A1,COc1ccc(CO[C@H]2[C@@H](O)[C@H](n3cnc4c(N)ncnc43)[C@@H](O)[C@@H]2COCc2ccccc2)cc1>>Nc1ncnc2c1ncn2[C@H]1[C@H](O)[C@H](O)[C@@H](COCc2ccccc2)[C@@H]1O,,CO,,Cl,,test
US20060199817A1,CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2.Clc1nncc2cc(Br)ccc12>>CC(C)(C)OC(=O)N1CC2CC1CN2c1nncc2cc(Br)ccc12,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20050113358A1,CCOC(=O)C(=CNc1ccc(C#N)cc1)C(=O)OCC>>CCOC(=O)c1cnc2ccc(C#N)cc2c1O,,CCCCCC,,c1ccc(Oc2ccccc2)cc1,,test
US04019892,O=C(O)CS.O=CCOc1ccc(Cl)cc1Cl>>O=C1CSC(COc2ccc(Cl)cc2Cl)O1,,CCOCC,,FB(F)F,,test
US06291131B1,O=C1C=CC(=O)O1.c1ccsc1>>O=C1OC(=O)C2C3C=CC(S3)C12,,C1CCOC1,,,,test
US20090149457A1,CCOC(=O)n1nc(NC(=O)c2ccccc2[N+](=O)[O-])c2cc(C(=O)NC(C)(C)c3ccccc3)sc21>>CCOC(=O)n1nc(NC(=O)c2ccccc2N)c2cc(C(=O)NC(C)(C)c3ccccc3)sc21,[Pd],CCOC(C)=O,,,,test
US04042617,C=C(c1ccc(-c2ccc(F)cc2)cc1)C(O)C(=O)OC>>COC(=O)C(=O)C(C)c1ccc(-c2ccc(F)cc2)cc1,,CO,,CC(=O)O,[Na],test
US20130096206A1,C=CCO[C@@H](CO)[C@@H](O)[C@H](O)CO>>OC[C@H](O)[C@@H](O)[C@H](O)CO,[Pt],CC(C)O,,,,test
US20140256707A1,Cn1ccc2ccc(S(=O)(=O)Cl)cc21.O=C1CCC(=O)N1Br>>Cn1cc(Br)c2ccc(S(=O)(=O)Cl)cc21,,ClCCl,,,,test
US04861769,O=C(OC(=O)C(F)(F)F)C(F)(F)F.O=CNc1nc(C(=NOC2CC2)C(=O)O)cs1>>O=C(O)C(=NOC1CC1)c1csc(NC(=O)C(F)(F)F)n1,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US05455253,CC1=C(C(=O)O)C(c2cccc([N+](=O)[O-])c2)C2=C(CCCC2=O)N1>>CC1=CC(c2cccc([N+](=O)[O-])c2)C2=C(CCCC2=O)N1,,CCO,,O=S(=O)(O)O,,test
US04507288,CCCCN(CCCC)CCC(O)c1cc2c(Cl)cc(Cl)cc2c2cc(C(F)(F)F)ccc12.O=P(O)(O)OC(CO)CO>>CCCCN(CCCC)CCC(O)c1cc2c(Cl)cc(Cl)cc2c2cc(C(F)(F)F)ccc12.O=P(O)(O)OC(CO)CO,,CCO,,,,test
US20120309738A1,CC(C)(C)OC(=O)NCc1ccc(Cl)c(Nc2nc3cc(Cl)c(N4CCC5(CC5)C4)cc3[nH]2)c1>>NCc1ccc(Cl)c(Nc2nc3cc(Cl)c(N4CCC5(CC5)C4)cc3[nH]2)c1,,C1CCOC1,,Cl,,test
US20100197651A1,CN(C)C=CC(=O)c1nn(-c2ccc(S(C)(=O)=O)cc2)ccc1=O.NNc1ccccc1>>CS(=O)(=O)c1ccc(-n2ccc(=O)c(-c3ccnn3-c3ccccc3)n2)cc1,,CO,,,,test
US20160152616A1,CC1(C)OC[C@H]([C@@H](O)[C@@H](O)Cn2c(=O)n3c4c(cccc42)C(C)(C)CC3)O1>>CC1(C)CCn2c(=O)n(C[C@H](O)[C@H](O)[C@H](O)CO)c3cccc1c32,,CC(=O)O,O,,,test
US20090105296A1,CC1(C)CC=C(c2nc(C3CC(C)(C)OC(C)(C)C3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1.Cl>>CC1(C)CC=C(c2nc(C3CC(C)(C)OC(C)(C)C3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1.Cl,,CCO,,,,test
US20100069347A1,CC(=O)O[C@@H](CC[C@H]1C(=O)N(c2ccc(CCC=O)cc2)[C@@H]1c1ccc(CCC2(OC(C)=O)COC(C)(C)OC2)cc1)c1ccc(F)cc1.Nc1nccs1>>CC(=O)O[C@@H](CC[C@H]1C(=O)N(c2ccc(CCCNc3nccs3)cc2)[C@@H]1c1ccc(CCC2(OC(C)=O)COC(C)(C)OC2)cc1)c1ccc(F)cc1,,CC(=O)O,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20080293684A1,CCOC(=O)CCc1ccc(OCCCCBr)cc1O>>O=C(O)CCc1ccc(OCCCCBr)cc1O,,C1CCOC1,,[Na+].[OH-],,test
US05606037,C=CC=COC(C)=O.COC(=O)C1(C(=O)OC)CC2=C(CO1)C(=O)C=CC2=O>>COC(=O)C1(C(=O)OC)CC2=C(CO1)C(=O)c1ccccc1C2=O,,Cc1ccccc1,,,,test
US04223032,CCOC(=O)c1[nH]nnc1Nc1ccccc1>>O=C(O)c1[nH]nnc1Nc1ccccc1,,[Na+],[OH-],,,test
US20140024650A1,CC(C)(C)OC(=O)N[C@H]1CCCO[C@@H]1CO.Oc1ccc(-c2ncc(Cl)cc2F)cc1>>CC(C)(C)OC(=O)N[C@H]1CCCO[C@@H]1COc1ccc(-c2ncc(Cl)cc2F)cc1,,Cc1ccccc1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20080312226A1,O=C(Nc1nncs1)OCC(Cl)(Cl)Cl.c1ccc(-c2nsc(N3CCNCC3)n2)cc1>>O=C(Nc1nncs1)N1CCN(c2nc(-c3ccccc3)ns2)CC1,,CS(C)=O,,CCN(C(C)C)C(C)C,O,test
US20090023935A1,CCOC(=O)CCNCC(=O)OCC.O=C(Cl)OCc1ccccc1>>CCOC(=O)CNC(CC(=O)OCC)C(=O)OCc1ccccc1,,CCO,O,O=C([O-])O.[Na+],,test
US20050130997A1,CCO.CCOc1c(C(=O)O)nc(O)n(C)c1=O>>CCOC(=O)c1nc(O)n(C)c(=O)c1OCC,,CCO,,CC(=O)Cl,,test
US20050004134A1,CC(C)n1nc(C#Cc2ccccc2)ccc1=O.O=S(=O)(O)O>>CC(C)n1nc(CC(=O)c2ccccc2)ccc1=O,,CC(=O)O,,,,test
US20030087926A1,C1=CCC=C1.CCC(=O)C(=O)[O-].Nc1ccc(Cl)cc1>>CCOC(=O)C1Nc2ccc(Cl)cc2C2C=CCC12,,CC#N,,O=C(O)C(F)(F)F,,test
US04985461,CC(C)(C)CNNC(=O)c1ccccc1.O=C(Cl)c1ccccc1>>CC(C)(C)CN(NC(=O)c1ccccc1)C(=O)c1ccccc1,,CCCCCC,Cc1ccccc1,[Na+].[OH-],,test
US20100190745A1,CCCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(B(O)O)cn1.CCOC(=O)c1cn(C2CN(C)C2)c2ccc(I)cc2c1=O>>CCCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2ccc3c(c2)c(=O)c(C(=O)OCC)cn3C2CN(C)C2)cn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,,O=C([O-])O.[Na+],,test
US05438139,CC(=O)Cl.Cc1ccc2ccccc2c1O>>CC(=O)c1cc(C)c(O)c2ccccc12,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US05041448,COC(=O)N1CCC(NCc2ccccc2)C(C)C1>>COC(=O)N1CCC(N)C(C)C1,[Pd],CO,,[H][H],,test
US05977105,OC(CCc1cccnc1)COc1ccc(/C=C/c2ccccc2)cc1>>OC(CCc1cccnc1)COc1ccc(CCc2ccccc2)cc1,[Pd],CCO,,,,test
US20040186077A1,Cc1nc(-c2ccccc2)c(C(F)P(=O)(OC(C)(C)C)OC(C)(C)C)c2c1OC(C)(C)OC2>>Cc1nc(-c2ccccc2)c(C(F)P(=O)(O)O)c(CO)c1O,,CC(=O)O,O,,,test
US20060211709A1,CNC(=O)c1nc(-c2ccc(OC3CCCCO3)cc2)cnc1N.O>>CNC(=O)c1nc(-c2ccc(OO)cc2)cnc1N,,CO,,Cl,,test
US20120184587A1,CC(=O)c1ccc(O)c(OC(F)(F)F)c1.COCCl>>COCOc1ccc(C(C)=O)cc1OC(F)(F)F,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04194003,COC(=O)c1cccn1C.O=C(Cl)c1cccc(Cl)c1>>COC(=O)c1cc(C(=O)c2cccc(Cl)c2)cn1C,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20080021032A1,COc1cc([C@@H](CC2CCCC2)C(=O)Nc2ccn(CCO[Si](C)(C)C(C)(C)C)n2)ccc1S(C)(=O)=O>>COc1cc([C@@H](CC2CCCC2)C(=O)Nc2ccn(CCO)n2)ccc1S(C)(=O)=O,Cl,CC(=O)O,,C1CCOC1,O,test
US20040058820A1,CCOC(=O)C(C)(C)Br.Oc1ccc(Cl)cn1>>CCOC(=O)C(C)(C)Oc1ccc(Cl)cn1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080167307A1,CCCCCCCNC(=O)Cc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1>>CCCCCCCNCCc1csc(SC(C)(C)C(=O)OC(C)(C)C)n1,,C1CCOC1,,CO,,test
US20160096791A1,CC(C)C1CC(c2ccccc2)(c2ccccc2)CN1C(=O)OC(C)(C)C>>CC(C)C1CC(c2ccccc2)(c2ccccc2)CN1,,ClCCl,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],,test
US20140135359A1,Cc1c(C=O)c(C)c2ncccc2c1C.[Li]CCCC>>C/C=C/c1c(C)c(C)c2cccnc2c1C,,Cc1ccccc1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20120015908A1,CI.COC(=O)c1cc(O)cc(OCc2ccccc2)c1>>COC(=O)c1cc(OC)cc(OCc2ccccc2)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140323537A1,CC#N.Cc1cc(-c2cn(C3CCCCO3)cc2CN(C)CCNC(=O)OC(C)(C)C)cc(C)c1OC(C)C>>Cc1cc(-c2n[nH]cc2CN(C)CCN)cc(C)c1OC(C)C,,Cl,,O,O=C(O)C(F)(F)F,test
US20100130545A1,CC#N.CCOc1ccc(CCN)cc1OCC>>CCNCCc1ccc(OCC)c(OCC)c1,[Rh],CO,,,,test
US20100311966A1,CC[C@H]1[C@@H](NC(=O)OC(C)(C)C)CN1C(c1ccccc1)c1ccccc1>>CC[C@@H]1NC[C@@H]1NC(=O)OC(C)(C)C,[Pd],,,,,test
US20120288492A1,CCN=C=O.CCOC(=O)c1nc(-c2ccc(O)cc2)nc(N2CCOCC2)c1OCC>>CCNC(=O)Oc1ccc(-c2nc(C(=O)OCC)c(OCC)c(N3CCOCC3)n2)cc1,,Cc1ccccc1,,,,test
US20080019915A1,COc1ccc(C2(C(=O)Cl)CC2)cc1.Cc1ccc(N)nc1Cl>>COc1ccc(C2(C(=O)Nc3ccc(C)c(Cl)n3)CC2)cc1,,ClCCl,,CCN(CC)CC,,test
US20070281955A1,CC(=O)Cl.Nc1cccc(-c2nc3sccn3c2-c2ccnc(N[C@@H]3CCCN(S(=O)(=O)c4ccc(Cl)cc4)C3)n2)c1>>CC(=O)Nc1cccc(-c2nc3sccn3c2-c2ccnc(N[C@@H]3CCCN(S(=O)(=O)c4ccc(Cl)cc4)C3)n2)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150141402A1,C=CC(=O)Cl.CC(C)n1cnc2c(Nc3cnn(C)c3)nc(N3C[C@@H](F)[C@H](N)C3)nc21>>C=CC(=O)N[C@@H]1CN(c2nc(Nc3cnn(C)c3)c3ncn(C(C)C)c3n2)C[C@H]1F,,ClCCl,,O=C([O-])O.[Na+],,test
US20030105098A1,COCCCCN.Clc1nc(Cl)c2ncn(C3CCCC3)c2n1>>COCCCCNc1nc(Cl)nc2c1ncn2C1CCCC1,,CCN(CC)CC,,,,test
US20090105482A1,CI.OCC1CCC2(CC1)OCCO2>>COCC1CCC(=O)CC1,,C1CCOC1,C1CCOC1,O,[H-].[Na+],test
US20140171312A1,CC(C)(C)OC(=O)NC1(C(=O)O)CC1.NCC(F)(F)F>>CC(C)(C)OC(=O)NC1(C(=O)NCC(F)(F)F)CC1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20040176430A1,C#CCNc1nc2ccc(OC(F)(F)F)cc2s1.Cc1ccc(C(=O)CBr)cc1>>C#CCN=c1sc2cc(OC(F)(F)F)ccc2n1CC(=O)c1ccc(C)cc1,,CC#N,,,,test
US20110312935A1,CC(C)(C)OC(=O)NCCCNc1ccc(C(=O)Nc2cc(Cl)ccn2)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)NCCCNc1ccc(C(=O)Nc2cc(Cl)ccn2)cc1N,,C1CCOC1,CO,,,test
US20140288088A1,Clc1ccc2cc(I)sc2n1.N#C[Cu]>>N#Cc1cc2ccc(Cl)nc2s1,,CN(C)C=O,,,,test
US20070037796A1,ClCCCl.NCCNS(=O)(=O)c1cc(-c2ccccc2)cc2cnccc12.O=CCCc1cccc2ccccc12>>Cl.Cl.O=S(=O)(NCCNCCCc1cccc2ccccc12)c1cc(-c2ccccc2)cc2cnccc12,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20080090818A1,COc1cc([N+](=O)[O-])ccc1C(=O)NCc1ccc(C)nc1>>COc1cc(N)ccc1C(=O)NCc1ccc(C)nc1,[Pd],CCO,CCOC(C)=O,O=C[O-].[NH4+],,test
US20120208815A1,CC(=O)OC(C)=O.Nc1ncc(Br)nc1C(=O)Nc1cnccc1N1CCCC(N)C1>>CC(=O)NC1CCCN(c2ccncc2NC(=O)c2nc(Br)cnc2N)C1,,ClCCl,,CCN(CC)CC,,test
US20140303161A1,CC1(C=O)COC1.N#CCC(=O)N1CCC[C@H]1Cn1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc21>>CC1(C=C(C#N)C(=O)N2CCC[C@H]2Cn2nc(-c3ccc(Oc4ccccc4)cc3F)c3c(N)ncnc32)COC1,,CCO,,C1CCNCC1,,test
US20100160317A1,CCOC(=O)c1c(C)c[nH]c1CC(=O)NC[C@@H](O)CN1CCOCC1>>CCOC(=O)c1c(C)c[nH]c1CCNC[C@@H](O)CN1CCOCC1,,C1CCOC1,,,,test
US20030229089A1,CNCCO.COc1ccc(CNc2nc(Cl)ncc2C(=O)c2cc(OC)c(OC)c(OC)c2)cc1Cl>>COc1ccc(CNc2nc(N(C)CCO)ncc2C(=O)c2cc(OC)c(OC)c(OC)c2)cc1Cl,,CN(C)C=O,,O,,test
US20130261103A1,CC(C)(C)OC(=O)N1CC(I)C1.O=[N+]([O-])c1cc[nH]n1>>CC(C)(C)OC(=O)N1CC(n2ccc([N+](=O)[O-])n2)C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110172216A1,CCOC(C)=C(C#N)C#N.CNN>>Cc1nn(C)c(N)c1C#N,,CCO,,,,test
US05631269,NN.O=C1C(=Cc2ccc(Cl)cc2)N2CCC1CC2>>Clc1ccc(-c2cc(C3CCNCC3)n[nH]2)cc1,,OCCO,,O,[K+].[OH-],test
US20090163472A1,CCOC(=O)C=C1c2ccccc2COc2cc(F)ccc21.O=C1CCC(=O)N1Br>>Fc1ccc2c(c1)OCc1ccccc1/C2=C\Br,,CC(C)O,O,CC(=O)O,[Li+].[OH-],test
US06248754B1,CC(C)(C)[Si](C)(C)OCCBr.COc1ccc(C(=O)Nc2ccc3c(c2Cl)CNCC3)cc1C(F)(F)F>>COc1ccc(C(=O)Nc2ccc3c(c2Cl)CN(CCO[Si](C)(C)C(C)(C)C)CC3)cc1C(F)(F)F,,CN(C)C=O,,,,test
US20100256097A1,C[Si](C)(C)C(F)(F)F.O=Cc1nccc(Cl)n1>>OC(c1nccc(Cl)n1)C(F)(F)F,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05624939,CC(C)(C)OC(=O)C1(C)CCC(c2ccccc2)N1C(=O)CNC(=O)Nc1cccc(C(=O)OCc2ccccc2)c1>>O=C(O)c1ccccc1,[Pd],CCOC(C)=O,,,,test
US20140329876A1,CI.CO[C@@H]1C(c2ccc(C#N)c(Cl)c2C)=NN2CC[C@H](O)[C@@H]12>>CO[C@H]1CCN2N=C(c3ccc(C#N)c(Cl)c3C)[C@@H](OC)[C@H]12,,C1CCOC1,,[H-].[Na+],,test
US20110172245A1,Cc1ccc(Oc2ccc3nc(N)sc3c2)cc1NC(=O)c1cccc(C(C)(C)C#N)c1.O=C(Cl)C1CC1>>Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)sc3c2)cc1NC(=O)c1cccc(C(C)(C)C#N)c1,,c1ccncc1,,,,test
US20080182844A1,Nc1ccc(-c2ccc3c(N)n[nH]c3n2)cc1.O=S(=O)(Cl)c1cccc(Cl)c1Cl>>Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cccc(Cl)c4Cl)cc3)ccc12,,CN(C)C=O,,CCN(CC)CC,O,test
US20140336185A1,Cc1ccc(-c2ccc(C(=O)O)cc2)cc1.O=Cc1ccc(O)cc1>>Cc1ccc(-c2ccc(C(=O)Oc3ccc(C=O)cc3)cc2)cc1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US05444080,CCCSc1ncc(C(C)C(=O)OCC)n1Cc1ccccc1Cl>>CCCSc1ncc(C(C)C(=O)O)n1Cc1ccccc1Cl,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US05994378,COC(=O)c1cc2ccccc2n1Cc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1>>CC(C)(C)c1csc(-c2cc3cc(Cn4c(C(=O)O)cc5ccccc54)ccc3o2)n1,,CCO,O,[Na+].[OH-],,test
US20110245303A1,CCOC(=O)Cc1ccc(OC)c(B2OC(C)(C)C(C)(C)O2)c1.O=Cc1cc(C(F)(F)F)ccc1Br>>CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2C=O)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,N#N,O=C([O-])[O-].[K+].[K+],test
US05962490,CC(C)c1ccc(-c2ccc(S(=O)(=O)Cl)s2)cc1.Cc1noc(N)c1Br>>Cc1noc(NS(=O)(=O)c2ccc(-c3ccc(C(C)C)cc3)s2)c1Br,,CO,ClC(Cl)Cl,,,test
US20090221653A1,C=CCN(CCc1ccccc1)C(=O)OC(C)(C)C.OCCS>>CC(C)(C)OC(=O)N(CCCSCCO)CCc1ccccc1,CC(C)(C#N)N=NC(C)(C)C#N,,,,,test
US06451973B1,CCN(CC)c1ccc(C(N)N(C[C@H](O)[C@@H](N)Cc2ccccc2)C(=O)OC(C)(C)C)cc1.Cl>>CCN(CC)c1ccc(CN(N)C[C@H](O)[C@@H](N)Cc2ccccc2)cc1.Cl,,C1COCCO1,,CN(C)C=O,,test
US05236952,COc1ccc(C=O)c(F)c1OC.NO>>COc1ccc(C#N)c(F)c1OC,,CCO,,Cl,,test
US20100173901A1,CC1(C)OB(c2cnn(CCF)c2)OC1(C)C.CC1Cc2ccc(Br)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1>>CC1Cc2ccc(-c3cnn(CCF)c3)cc2CN1c1cc(N2CCN(C)CC2)nc(N)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,O,C1COCCO1,O=C([O-])O.[Na+],test
US20120214767A1,C=C[Sn](CCCC)(CCCC)CCCC.CC(C)Oc1ccc(-c2onc3c2CCc2cc(Br)ccc2-3)cc1C#N>>C=Cc1ccc2c(c1)CCc1c-2noc1-c1ccc(OC(C)C)c(C#N)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,[Cl-].[Li+],,test
US05780642,C=CC(=O)Cl.CC(C)(N)c1ccc(OCc2ccccc2)cc1>>C=CC(=O)NC(C)(C)c1ccc(OCc2ccccc2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20070004675A1,Nc1ccc(Oc2ccnc3ccsc23)c(F)c1.O=C(O)CC(=O)Nc1ccccc1>>O=C(CC(=O)Nc1ccc(Oc2ccnc3ccsc23)c(F)c1)Nc1ccccc1,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20070099936A1,CCOC(C)=O.NC1c2ccccc2C(=O)N1Cc1ccccc1>>CC(=O)O.NC1c2ccccc2C(=O)N1Cc1ccccc1,,CO,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20130190332A1,COC(=O)c1ccn2c(-c3ccccc3)c(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)nc2c1.N>>CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4cc(C(N)=O)ccn4c3-c3ccccc3)cc2)CCC1,,CO,,,,test
US20140288040A1,COc1c(F)ccc(CNc2ccccn2)c1F>>Oc1c(F)ccc(CNc2ccccn2)c1F,,ClCCl,,BrB(Br)Br,,test
US04959460,CC(=O)O[C@H]1CO[C@H](CO)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.ClC(Cl)(Cl)Cl>>CC(=O)O[C@H]1CO[C@H](CCl)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,c1ccncc1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20130137865A1,CN(CCNS(=O)(=O)c1cccc(-c2noc(-c3cnn(C)c3COc3ccc(F)cn3)n2)c1)C(=O)OC(C)(C)C>>CNCCNS(=O)(=O)c1cccc(-c2noc(-c3cnn(C)c3COc3ccc(F)cn3)n2)c1,,C1COCCO1,,Cl,,test
US20060223850A1,Brc1ccccc1Br.CC(=O)c1ccc(B(O)O)cc1>>CC(=O)c1ccc(-c2ccccc2Br)cc1,,CCOC(C)=O,,,,test
US20040023947A1,CCOC(=O)C1CNCCc2c1[nH]c1ccccc21.O=C(Cl)c1ccc(F)cc1>>CCOC(=O)C1CN(C(=O)c2ccc(F)cc2)CCc2c1[nH]c1ccccc21,,ClCCl,,,,test
US05397781,C=CC(=O)O.CCCNc1ccccc1>>CCCN(CCC(=O)O)c1ccccc1,,O,,[Na+].[OH-],,test
US07531553B2,C=O.CC(=O)Nc1ccc(C(F)(F)F)c(OC[C@H]2CCCN2)c1>>CC(=O)Nc1ccc(C(F)(F)F)c(OC[C@H]2CCCN2C)c1,CC(=O)O,CC#N,,[BH3-]C#N.[Na+],,test
US20050184274A1,C=CC(O)C=C.O=C(O)CCCCCOCc1ccc(I)s1>>C=CC(C=C)OC(=O)CCCCCOCc1ccc(I)s1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20110046349A1,CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O>>CC(C)C[C@H](N)C(=O)O,,ClCCl,,CCN(C(C)C)C(C)C,CO,test
US20090018114A1,FC1(F)CNC1.Nc1cccc(F)c1C(=O)O.O=C(Cl)C12CC3CC(CC(C3)O1)C2>>O=C(c1c(F)cccc1NC(=O)C12CC3CC(CC(C3)O1)C2)N1CC(F)(F)C1,,CC#N,,CCN(CC)CC,Cl,test
US20100222344A1,C[C@@H](O)C(=O)N1CCOCC1.Oc1ccc(Nc2ncnc3cccc(F)c23)cc1Cl>>C[C@@H](Oc1cccc2ncnc(Nc3ccc(O)c(Cl)c3)c12)C(=O)N1CCOCC1,,CC(=O)N(C)C,,CC(=O)O,[H-].[Na+],test
US20130338124A1,ClC(Cl)(Cl)C(Cl)(Cl)Cl.Cn1c(=O)c2cn(Cc3ccc(-c4ccncc4)cc3)nc2n(CC(C)(C)C)c1=O>>Cn1c(=O)c2c(Cl)n(Cc3ccc(-c4ccncc4)cc3)nc2n(CC(C)(C)C)c1=O,,C1CCOC1,ClCCl,O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20140336377A1,Cl.N#Cc1cc(OCC(F)(F)F)ccn1>>Cl.NCc1cc(OCC(F)(F)F)ccn1,[Pd],CO,,,,test
US04190666,CC(C)(C)Oc1ccc(-c2nc(S(=O)(=O)C(F)(F)C(F)F)[nH]c2-c2ccc(OC(C)(C)C)cc2)cc1>>O=S(=O)(c1nc(-c2ccc(O)cc2)c(-c2ccc(O)cc2)[nH]1)C(F)(F)C(F)F,,O,,O=C(O)C(F)(F)F,,test
US20100029657A1,CN(C)C=CC(=O)c1ccc(N2CC3CC2CN3C(=O)OC(C)(C)C)cc1F.Nc1[nH]nc(-c2ccncc2)c1-c1ccc(F)c2[nH]ncc12>>CC(C)(C)OC(=O)N1CC2CC1CN2c1ccc(-c2ccnc3c(-c4ccc(F)c5[nH]ncc45)c(-c4ccncc4)nn23)c(F)c1,,CO,,O=C(O)C(F)(F)F,,test
US20130196971A1,CC(C)(C)OC(=O)N1CC(Cn2cnnc2-c2ccc(Br)cc2F)C1.O=C(Cl)C1CC1>>O=C(C1CC1)N1CC(Cn2cnnc2-c2ccc(Br)cc2F)C1,,ClCCl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20100069630A1,COC(=O)c1ccc(/C=C(\COc2cccc3ccccc23)C(=O)NC2CCN(C)CC2)cc1>>CN1CCC(NC(=O)/C(=C/c2ccc(C(=O)O)cc2)COc2cccc3ccccc23)CC1,,O,,[Li+].[OH-],,test
US20080113978A1,CCC(CC)c1cc(C)nn2c(-c3sc(Br)nc3C)c(C)nc12.OB(O)c1ccc(OC(F)(F)F)cc1>>CCC(CC)c1cc(C)nn2c(-c3sc(-c4ccc(OC(F)(F)F)cc4)nc3C)c(C)nc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20080312459A1,II.OCCCCCCCCCCCCc1ccc(I)cc1>>ICCCCCCCCCCCCc1ccc(I)cc1,,ClCCl,c1ccccc1,c1c[nH]cn1,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110021537A1,CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)c2cc(OCC(=O)N3CC(F)(F)C[C@H]3C(=O)O)n(-c3ccccc3)n2)CC1.NC1CCC1>>CCOC(=O)N1CCN(C(=O)[C@H](CCC(=O)O)NC(=O)c2cc(OCC(=O)N3CC(F)(F)C[C@H]3C(=O)NC3CCC3)n(-c3ccccc3)n2)CC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070249642A1,ClCCCBr.O=c1[nH]cc(-c2ccccc2)c(=O)[nH]1>>O=c1[nH]c(=O)n(CCCCl)cc1-c1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120010193A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1NCCNC1c1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCNC(=O)C1c1ccc(F)cc1,,ClCCl,,[Na+].[OH-],,test
US20130190340A1,C=C(CC)C(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl.CC(C)(C)OC(=O)N=C(NCCCC(NC(=O)OC(C)(C)C)C(=O)NCCCCCCN)NC(=O)OC(C)(C)C>>C=C(CC)C(=O)c1ccc(OCC(=O)NCCCCCCNC(=O)C(CCCNC(=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)c(Cl)c1Cl,,CN(C)C=O,,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US20070032470A1,CC(N)c1ccc(F)cc1.COC(=O)c1cc(Br)cc(C(=O)O)c1>>COC(=O)c1cc(Br)cc(C(=O)NC(C)c2ccc(F)cc2)c1,,CCOC(C)=O,CN(C)C=O,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20150313864A1,CCOC(=O)C(=O)Cl.CNCCOC>>CCOC(=O)C(=O)N(C)CCOC,,CCOCC,,CCN(CC)CC,,test
US06121285,CC(C)(C#N)N=NC(C)(C)C#N.CCCCCC.CCOC(=O)/C=C(\C)C1(C(=O)OCC)CCC1.ClC(Cl)Cl>>CCOC(=O)C1(C2=CC(=O)N([C@@H](C)c3ccccc3)C2)CCC1,,CCOC(C)=O,ClC(Cl)Cl,O=C([O-])O.[Na+],,test
US20090246808A1,CC(=O)O.Nc1cccc2nc3ccccc3nc12>>CC(=O)Nc1cccc2nc3ccccc3nc12,,CC(=O)O,,CC(=O)OC(C)=O,,test
US20130296292A1,CC(C)(C)OC(=O)NCCC(=O)O.NNC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1>>CC(C)(C)OC(=O)NCCC(=O)NNC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06624172B2,CCOCc1nc2cnc3cccnc3c2n1Cc1ccccc1.O=C(OO)c1cccc(Cl)c1>>CCOCc1nc2c[n+]([O-])c3cccnc3c2n1Cc1ccccc1,,ClC(Cl)Cl,,[Al],,test
US04971963,Cl.N=C(N)CCl.S=C1CSC(=S)N1>>Cl.N=C(N)CSc1csc(S)n1,,CCO,,[Na+].[OH-],,test
US20150191462A1,CC(C)(C)O.O=C(O)c1cccc(OC(F)F)n1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)Nc1cccc(OC(F)F)n1,,CCOC(C)=O,Cc1ccccc1,CCN(CC)CC,,test
US20090054407A1,CC(C)(C)OC(=O)n1c(-c2ccc(O)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21.O=S(=O)(Cl)c1ccsc1>>CC(C)(C)OC(=O)n1c(-c2ccc(OS(=O)(=O)c3ccsc3)c3c2C(=O)NC3)cc2cc(CN3CCCCC3)ccc21,,CC#N,,CCN(CC)CC,,test
US20050165054A1,COc1cc(C)c2c(Oc3cccc(C(F)(F)F)c3)c(OC)cc(NC(C)CCC[N+](=O)[O-])c2n1.O=C(O)CCC(=O)O>>COc1cc(C)c2c(Oc3cccc(C(F)(F)F)c3)c(OC)cc(NC(C)CCCN)c2n1.O=C(O)CCC(=O)O,[Pd],CCO,,[H][H],,test
US20060069110A1,CSc1nccc(N(C)c2nccc(-c3ccccc3)n2)n1.O=C(OO)c1cccc(Cl)c1>>CN(c1ccnc(S(C)=O)n1)c1nccc(-c2ccccc2)n1,,ClC(Cl)Cl,,,,test
US20120088767A1,COC(=O)c1cc(N2CCOCC2)cc2c1nc(C(F)F)n2Cc1cccc(Cl)c1Cl>>O=C(O)c1cc(N2CCOCC2)cc2c1nc(C(F)F)n2Cc1cccc(Cl)c1Cl,,C1CCOC1,,[Li+].[OH-],,test
US20100311730A1,Cc1ccc(S(=O)(=O)OCC2(F)CCN(C(=O)OC(C)(C)C)CC2)cc1.Nc1cc(Cl)ncc1I>>CC(C)(C)OC(=O)N1CCC(F)(CNc2cc(Cl)ncc2I)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20100137281A1,CCOC(=O)Cl.CCc1cc(C(=O)OC)c(N)s1>>CCOC(=O)Nc1sc(CC)cc1C(=O)OC,,Cc1ccccc1,,,,test
US20050250798A1,O=C1Nc2ccc([N+](=O)[O-])cc2C1=O.OCCCO>>O=C1Nc2ccc([N+](=O)[O-])cc2C12OCCCO2,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20090186879A1,CC(C)(C)OC(=O)NCCCNc1c([N+](=O)[O-])cccc1[N+](=O)[O-]>>CC(C)(C)OC(=O)NCCCNc1c(N)cccc1N,[Pd],C1CCOC1,,,,test
US20120208817A1,CCOC(=O)Cc1ccsc1.Cn1nccc1C(=O)O>>CCOC(=O)C(C(=O)c1ccnn1C)c1ccsc1,,CCOC(C)=O,CN(C)C=O,O=C(n1ccnc1)n1ccnc1,[H-].[Na+],test
US20050245532A1,CC(C)(C(=O)O)N1CCN(c2ccc(C(F)(F)F)cn2)CC1.CCN(C(C)C)C(C)C.CCN=C=NCCCN(C)C.ClCCl.Oc1cccc2[nH]nnc12>>CC(C)(C(=O)NC1C2CC3CC(C2)CC1C3)N1CCN(c2ccc(C(F)(F)F)cn2)CC1,,ClCCl,,Cl,O,test
US20120172351A1,CC1Oc2ncccc2C1=O>>CC1Oc2ncccc2C1O,,C1CCOC1,CO,[BH4-].[Na+],,test
US05273986,ClCc1csc(C2CCC2)n1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>[Cl-].c1ccc([P+](Cc2csc(C3CCC3)n2)(c2ccccc2)c2ccccc2)cc1,,Cc1ccccc1,,,,test
US20110021518A1,CCOC(=O)CC(=O)c1ccc([N+](=O)[O-])c(F)c1.COC(OC)N(C)C>>CCOC(=O)C(=CN(C)C)C(=O)c1ccc([N+](=O)[O-])c(F)c1,,Cc1ccccc1,,,,test
US20040116424A1,CCCCc1c(CBr)nc(Cl)nc1-c1ccccc1.COC(=O)c1ccc(CNCc2ccc3c(c2)OCCO3)cc1>>CCCCc1c(CN(Cc2ccc(C(=O)OC)cc2)Cc2ccc3c(c2)OCCO3)nc(Cl)nc1-c1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20120245178A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.CCBr>>CCn1cc(B2OC(C)(C)C(C)(C)O2)cn1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20130252940A1,CC(=O)OC(C)=O.COC(=O)c1cc(OC)c(OC)cc1N>>COC(=O)c1cc(OC)c(OC)cc1NC(C)=O,,CCCCCCC,,,,test
US20140018313A1,COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc3cc(-c4ccc5c(c4)CCc4nc(C6CCCN6C(=O)C(NC(=O)OC)C(C)C)[nH]c4-5)ccc3c2)[nH]1)C(C)C>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc3cc(-c4ccc5c(ccc6nc([C@@H]7CCCN7C(=O)[C@@H](NC(=O)OC)C(C)C)[nH]c65)c4)ccc3c2)[nH]1)C(C)C,O=[Mn]=O,ClCCl,,,,test
US20060252759A1,BrC(Br)(Br)Br.C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3cc(Br)c(CO)nc3N21>>C[C@@H]1CN(C(=O)OC(C)(C)C)C[C@H]2Cc3cc(Br)c(CBr)nc3N21,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20040034036A1,COc1ccc(S(=O)(=O)Nc2cc(Cl)cc(Cl)c2OC)cc1N1CCNCC1.Cc1ccc(S(=O)(=O)O)cc1>>COc1ccc(S(=O)(=O)Nc2cc(Cl)cc(Cl)c2OC)cc1N1CCNCC1.Cc1ccc(S(=O)(=O)O)cc1,,CCO,,O,,test
US20120208859A1,CO.O=[N+]([O-])c1c(F)cc(F)c(F)c1Nc1ccc(I)cc1F>>COc1cc(F)c([N+](=O)[O-])c(Nc2ccc(I)cc2F)c1F,,C1CCOC1,CO,C[O-].[Na+],,test
US20120101243A1,C=CCC(CC=C)(CC=C)c1ccc(I)cc1.N#C[Cu]>>C=CCC(CC=C)(CC=C)c1ccc(C#N)cc1,,CN(C)C=O,,[NH4+].[OH-],,test
US20030166628A1,O=CC1=C(c2ccc3sccc3c2)N2CCN=C2S1>>OCC1=C(c2ccc3sccc3c2)N2CCN=C2S1,,CO,,O,[BH4-].[Na+],test
US20130190249A1,CC(C)(C)N.O=[N+]([O-])c1cc(F)cc(S(=O)(=O)Cl)c1>>CC(C)(C)NS(=O)(=O)c1cc(F)cc([N+](=O)[O-])c1,,C1COCCO1,,,,test
US20090203737A1,N#C[C@H]1CCCN(C(=O)c2ccc(F)nc2)C1.NO>>N=C(NO)[C@H]1CCCN(C(=O)c2ccc(F)nc2)C1,,CCO,,,,test
US20160096827A1,CC(C)(O)c1cc(Nc2ncnc(Cl)n2)ccn1.CC1(C)OB(c2ccc(O[C@H]3CCN(C(=O)CO)C[C@H]3F)c(C#N)c2)OC1(C)C>>CC(C)(O)c1cc(Nc2ncnc(-c3ccc(O[C@H]4CCN(C(=O)CO)C[C@H]4F)c(C#N)c3)n2)ccn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20120065196A1,CC(C)(C)OC(=O)N1CCC(C(=O)NCCNC(=O)c2cn(-c3ccccc3)nc2C(F)(F)F)CC1.Cl>>Cl.O=C(NCCNC(=O)C1CCNCC1)c1cn(-c2ccccc2)nc1C(F)(F)F,,C1COCCO1,ClCCl,,,test
US20050176700A1,CC(=O)N1CC2CC(c3ccc(OCCOc4cc(F)ccc4Br)cc3)=C(C(=O)O)C(C1)N2C(=O)OC(C)(C)C(Cl)(Cl)Cl.CCOC(=O)C1=C(c2ccc(OCCOc3cccc(F)c3Cl)cc2)CC2CN(C(C)=O)CC1N2C(=O)OC(C)(C)C(Cl)(Cl)Cl>>CC(=O)N1CC2CC(c3ccc(OCCOc4cc(F)ccc4Cl)cc3)=C(C(=O)O)C(C1)N2C(=O)OC(C)(C)C(Cl)(Cl)Cl,,CCO,,[Na+].[OH-],,test
US20110009389A1,COC(=O)CCS(=O)(=O)Cl.Clc1ccc2c(c1)CCNC2>>COC(=O)CCS(=O)(=O)N1CCc2cc(Cl)ccc2C1,,CC#N,,CCN(CC)CC,Cl,test
US20160031899A1,CC(C)(C)[Si](O[C@H]1CC[C@](C)([C@H]2CC[C@@]3(C)[C@@H](CC[C@@]3(O)c3ccccc3)[C@@H]2CO)[C@@H](CO)C1)(c1ccccc1)c1ccccc1>>C[C@]1([C@H]2CC[C@@]3(C)[C@@H](CC[C@@]3(O)c3ccccc3)[C@@H]2CO)CC[C@H](O)C[C@@H]1CO,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100216986A1,Ic1ccc[se]1.OB(O)c1ccc(OC(F)(F)F)cc1>>FC(F)(F)Oc1ccc(-c2ccc[se]2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20070155721A1,CCOC(=O)c1cc2c(Oc3ccccc3)cccc2[nH]1>>O=C(O)c1cc2ccccc2n1Oc1ccccc1,,CO,O,[Li+].[OH-],,test
US20140179698A1,CCO.Cc1ccc(CCl)cc1[N+](=O)[O-]>>CCOCc1ccc(C)c([N+](=O)[O-])c1,,O,,C,C[O-].[Na+],test
US20110160056A1,CC(C)(C)C(=O)C(CCCCOc1cc(Cl)ccc1F)n1cncn1>>CC(C)(C)C(O)C(CCCCOc1cc(Cl)ccc1F)n1cncn1,,CO,,[BH4-].[Na+],[Cl-].[NH4+],test
US20160108037A1,CCI.O=C(O)c1ccc(C(F)(F)F)n2c(=S)[nH]nc12>>CCSc1nnc2c(C(=O)O)ccc(C(F)(F)F)n12,,CN(C)C=O,,,,test
US20160046618A1,COC(=O)c1ncc(O[C@@H](C)c2ncco2)nc1C>>Cc1nc(O[C@@H](C)c2ncco2)cnc1C(=O)O,,C1CCOC1,O,Cl,[Li+].[OH-],test
US06399629B1,CC(C)(C)OC(=O)NCC(=O)N[C@@H]1C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1.Oc1c(F)c(F)c(F)c(F)c1F>>CC(C)(C)OC(=O)NCC(=O)N[C@@H]1C[C@@H](C(=O)Oc2c(F)c(F)c(F)c(F)c2F)N(C(=O)OC(C)(C)C)C1,,CCOC(C)=O,,,,test
US20110262963A1,CC(=O)c1ccc(O)cc1[N+](=O)[O-].CCOC(=O)CBr>>CCOC(=O)COc1ccc(C(C)=O)c([N+](=O)[O-])c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150031679A1,COC(=O)c1ccc2nc(Cl)c(-c3ccc(F)cc3)nc2c1.c1ccc(N2CCNCC2)nc1>>COC(=O)c1ccc2nc(N3CCN(c4ccccn4)CC3)c(-c3ccc(F)cc3)nc2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070249670A1,Cc1cc(C)c(N=C=O)c(C)c1.Nc1cc(-c2ccc(OC(F)(F)F)cc2)sc1C(=O)O>>Cc1cc(C)c(NC(=O)Nc2cc(-c3ccc(OC(F)(F)F)cc3)sc2C(=O)O)c(C)c1,,CN(C)C=O,,CCN(CC)CC,O,test
US20150344468A1,Brc1csc(Br)n1.O=Cc1ccc2[nH]c(=O)sc2c1>>O=c1[nH]c2ccc(C(O)c3nc(Br)cs3)cc2s1,,C1CCOC1,CCOCC,CC(C)[Mg]Cl,[Cl-].[NH4+],test
US20110053162A1,CC(=O)N(/C=C/C=C/C1=C[NH+]2CCc3ccc(S(=O)(=O)[O-])c(c32)C1(C)C)c1ccccc1.CC1=C[NH+]2CCc3ccc(S(=O)(=O)[O-])c(c32)C1(C)CCCCCC(=O)O>>CC1(CCCCCC(=O)O)C(/C=C/C=C/C=C2/N3CCCc4ccc(S(=O)(=O)[O-])c(c43)C2(C)C)=C[NH+]2CCc3ccc(S(=O)(=O)O)c1c32,,CC(=O)OC(C)=O,,c1ccncc1,,test
US20140135338A1,CCOC(=O)CCN.Cc1cc2ccccc2nc1NC(c1ccc(C(=O)O)cc1)C1CC(C)(C)C1>>CCOC(=O)CCNC(=O)c1ccc(C(Nc2nc3ccccc3cc2C)C2CC(C)(C)C2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US05387685,BrCCCCCCCCCCCBr.COc1ccc(C(C#N)Sc2ccc(C)cc2)cc1OC>>COc1ccc(C(C#N)(CCCCCCCCCCCBr)Sc2ccc(C)cc2)cc1OC,,C1CCOC1,,[H-].[Na+],,test
US20070129347A1,CN(C)C1(c2ccccc2)CCC(=CC(=O)NCc2ccc(F)cc2)CC1.C[Si](C)(C)Cl>>CN(C)C1(c2ccccc2)CCC(=CC(=O)NCc2ccc(F)cc2)CC1.Cl,,CCC(C)=O,,,,test
US20120142717A1,CCOC(=O)/C(=C\O)CC.N=C(N)OCCc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cc1>>CCc1c[nH]c(OCCc2ccc(Oc3ccc(Cl)c(C(F)(F)F)c3)cc2)nc1=O,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20020086871A1,CI.S=c1[nH]c2cc(Br)ccc2o1>>CSc1nc2cc(Br)ccc2o1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130216498A1,CC(C)(C)OC(=O)N1CCC[C@@H](N)C1.Fc1ccc2ncc(-c3ncc(Cl)c(Cl)n3)n2c1>>CC(C)(C)OC(=O)N1CCC[C@@H](Nc2nc(-c3cnc4ccc(F)cn34)ncc2Cl)C1,,CCO,,,,test
US20120010190A1,Cc1cc(Cl)ccc1C(CC(=O)c1ccc(=O)n(C)c1)c1ccc(N)cc1.O=C(Cl)CCCCl>>Cc1cc(Cl)ccc1C(CC(=O)c1ccc(=O)n(C)c1)c1ccc(NC(=O)CCCCl)cc1,,ClCCl,c1ccncc1,,,test
US20040254182A1,CC(=O)Nc1ccc(O)cc1.CC(C)OC(=O)C(OC(=O)Cl)OC(=O)C(C)C>>CC(=O)Nc1ccc(OC(=O)OC(OC(=O)C(C)C)C(=O)OC(C)C)cc1,,ClCCl,,CCO,[K+].[OH-],test
US05843957,CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(O)c2)c2cccnc21.OCCc1ccccn1>>CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(OCCc3ccccn3)c2)c2cccnc21,,C1CCOC1,O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140275173A1,OCC12CCC(c3cccc(Oc4ccccc4)c3)(CC1)OC2>>O=CC12CCC(c3cccc(Oc4ccccc4)c3)(CC1)CO2,,CCOC(C)=O,ClCCl,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US20140309210A1,C[Si](C)(C)CCOCn1nc(C(=O)O)c2ccc(Br)cc21.N#Cc1cccc(Cn2cc(N)cn2)c1>>C[Si](C)(C)CCOCn1nc(C(=O)Nc2cnn(Cc3cccc(C#N)c3)c2)c2ccc(Br)cc21,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05571810,CC(=O)Cl.CS(=O)(=O)c1ccc(-c2ccsc2-c2ccc(F)cc2)cc1>>CC(=O)c1cc(-c2ccc(S(C)(=O)=O)cc2)c(-c2ccc(F)cc2)s1,Cl[Ti](Cl)(Cl)Cl,c1ccccc1,,,,test
US20040058978A1,CC(=O)N(C)c1ccc(N)cc1.CCOC(=C1C(=O)N(C(C)=O)c2ccccc21)c1ccccc1>>CC(=O)N(C)c1ccc(N/C(=C2\C(=O)Nc3ccccc32)c2ccccc2)cc1,,CN(C)C=O,CO,[Na+].[OH-],,test
US20060199800A1,CC#CCOc1ncnc(Cl)c1Cl.CC1CNCC(C)C1>>CC#CCOc1ncnc(N2CC(C)CC(C)C2)c1Cl,,CCO,,,,test
US20110224193A1,Nc1ccc(Cl)nc1.O=C(O)c1nc(-c2ccccc2)oc1C(F)(F)F>>O=C(Nc1ccc(Cl)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F,,C1CCOC1,CC#N,ClCCCl,On1nnc2ccccc21,test
US20060178315A1,C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)ON1C(=O)CCC1=O.N[C@@H](CC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O>>C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O,,CCOC(C)=O,CN(C)C=O,,,test
US20060194969A1,CC(=O)OC(C)=O.Nc1c([N+](=O)[O-])cc(Br)cc1[N+](=O)[O-]>>CC(=O)Nc1c([N+](=O)[O-])cc(Br)cc1[N+](=O)[O-],,CS(=O)(=O)O,,,,test
US20160152605A1,CCCC[Sn](CCCC)(CCCC)c1ccccn1.COC(=O)c1ccc(Br)cc1OC>>COC(=O)c1ccc(-c2ccccn2)cc1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US04730052,C/C(N)=C/C(=O)[O-].CC(=O)CC(=O)OCCC#N.O=Cc1ccccc1[N+](=O)[O-]>>CC1=C(C(=O)O)C(c2ccccc2[N+](=O)[O-])C(C(=O)OCCC#N)=C(C)N1,,CC(C)O,,,,test
US20090069297A1,CC1(C)OC(=O)CC(=O)O1.COC(OC)OC.COc1nccc(N)c1Br>>COc1nccc(NC=C2C(=O)OC(C)(C)OC2=O)c1Br,,CCCCCC,,,,test
US20020137928A1,CN1CCCc2c(ccn2CCCN2CCN(c3ccc(F)cc3)CC2)S1(=O)=O.NO>>CN1CCC(=NO)c2c(ccn2CCCN2CCN(c3ccc(F)cc3)CC2)S1(=O)=O,,CO,,Cl,CC(=O)[O-].[Na+],test
US04645527,CN(C)S(=O)(=O)c1ccccc1Cl.O=S(=O)(Cl)Cl>>CN(C)S(=O)(=O)c1c(Cl)cccc1S(=O)(=O)Cl,,CCOCC,,[Li]CCCC,,test
US05166152,CI.N#CC(C(=O)Nc1ccccc1)C(=O)c1nn(-c2ccccc2)c2c1CSc1ccc(C(=O)O)cc1-2>>COC(=O)c1ccc2c(c1)-c1c(c(C(=O)C(C#N)C(=O)Nc3ccccc3)nn1-c1ccccc1)CS2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US05661183,Cc1c(Cl)c(O)c([N+](=O)[O-])c(C(=O)O)c1Cl>>Cc1c(Cl)c(O)c(N)c(C(=O)O)c1Cl,[Pd],CC(=O)O,,CO,Cl,test
US20040106655A1,C1CC2(CCN1)OCCO2.O=[N+]([O-])c1ccc(F)cc1>>O=[N+]([O-])c1ccc(N2CCC3(CC2)OCCO3)cc1,,O,,CCN(C(C)C)C(C)C,,test
US06248870B1,COc1ccc(-c2cc(-c3ccccn3)nc(-c3cccc(C(=O)O)n3)c2)cc1.O=S(Cl)Cl>>COc1ccc(-c2cc(-c3ccccn3)nc(-c3cccc(C(=O)Cl)n3)c2)cc1,,ClCCl,,,,test
US09051310B2,CC(C)(C)OC(=O)N[C@H]1CCCC[C@@H]1O.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1N,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060205736A1,COC(=O)C1Cc2cccc(S(=O)(=O)Cl)c2C1.C[C@H]1CN(c2ccc(Cl)c(Br)c2)C[C@@H](C)N1>>COC(=O)C1Cc2cccc(S(=O)(=O)N3[C@@H](C)CN(c4ccc(Cl)c(Br)c4)C[C@H]3C)c2C1,,O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20050197373A1,CCc1cc(NC(=O)Oc2ccccc2)cc(-c2nnnn2C)c1.Fc1ccc(C[C@@H]2CCCN(C3CCC4CNCC43)C2)cc1>>CCc1cc(NC(=O)N2CC3CCC(N4CCC[C@@H](Cc5ccc(F)cc5)C4)C3C2)cc(-c2nnnn2C)c1,,CCOC(C)=O,,CC#N,CCN(CC)CC,test
US05004748,COC(=O)c1cc(C(=O)OC)c(C#CCCO)cn1>>COC(=O)c1cc(C(=O)OC)c(CCCCO)cn1,[Pd],CO,,,,test
US20100137281A1,CCc1cc2c(=O)n(Cc3ccc(OC)cc3OC)c(=O)[nH]c2s1.N#Cc1ccccc1-c1ccc(CBr)cc1F>>CCc1cc2c(=O)[nH]c(=O)n(Cc3ccc(-c4ccccc4C#N)c(F)c3)c2s1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090048306A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COC(C)COc1ccc(F)cc1Br>>COC(C)COc1ccc(F)cc1B1OC(C)(C)C(C)(C)O1,,CN(C)C=O,,CC(=O)[O-].[K+],,test
US04391807,C1CCNCC1.Clc1nn2ccnc2c2c1CCCC2>>c1cn2nc(N3CCCCC3)c3c(c2n1)CCCC3,,ClCCl,,CC(C)=O,,test
US04708733,CCOC(=O)C(C(=O)OCC)C(=O)C(C)Cl.Cc1cc(Cl)ccc1O>>CCOC(=O)C(C(=O)OCC)C(=O)C(C)Oc1ccc(Cl)cc1C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030181334A1,Clc1ccnc(Cl)n1.N#Cc1cc(C#N)cc(Oc2cccc(O)c2)c1>>N#Cc1cc(C#N)cc(Oc2cccc(Oc3ccnc(Cl)n3)c2)c1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20060235015A1,O=C1NC(=O)C(c2ccccc2)=C1Nc1ccc(OC(F)(F)F)cc1.OCC(F)(F)F>>O=C1C(Nc2ccc(OC(F)(F)F)cc2)=C(c2ccccc2)C(=O)N1CC(F)(F)F,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090299072A1,CC(C)CC(C(=O)OCC1CC1)c1ccc(N)c(OCC2CC2)c1.O=C1CCC(=O)N1Cl>>CC(C)CC(C(=O)OCC1CC1)c1cc(Cl)c(N)c(OCC2CC2)c1,,ClC(Cl)Cl,,O=C([O-])[O-].[K+].[K+],,test
US20070054916A1,Nc1ccc(C(F)(F)F)c(Cl)c1.O=C(Cl)c1cccc(C(F)(F)F)c1>>O=C(Nc1ccc(C(F)(F)F)c(Cl)c1)c1cccc(C(F)(F)F)c1,,ClCCl,,CCN(CC)CC,,test
US20160122342A1,CC(C)(C)OC(=O)N1CC2(CC(=O)C2)C1.CC=O.COc1nc(C)cc2c1CNC(=O)c1cccc(N)c1CC=CCC2>>CCN(c1cccc2c1CC=CCCc1cc(C)nc(OC)c1CNC2=O)C1CC2(C1)CN(C(=O)OC(C)(C)C)C2,,ClCCCl,,CC(=O)O,O=C([O-])O.[Na+],test
US07105558B2,COC(=O)c1cccc(NC(=O)c2nn(-c3c(Cl)cccc3Cl)nc2COc2ccccc2)c1>>O=C(O)c1cccc(NC(=O)c2nn(-c3c(Cl)cccc3Cl)nc2COc2ccccc2)c1,,C1CCOC1,O,[Li+].[OH-],,test
US20080132510A1,CCCc1c(C)ncc(Br)c1NC(C)=O.O=C(OO)c1cccc(Cl)c1>>CCCc1c(CO)ncc(Br)c1NC(C)=O,,ClC(Cl)Cl,,ClCCl,,test
US05045552,Cc1c(OCCOCc2ccccc2)ccnc1CO.O=S(Cl)Cl>>Cc1c(OCCOCc2ccccc2)ccnc1CCl,,ClC(Cl)Cl,,O=C([O-])[O-].[Na+].[Na+],,test
US20050209301A1,CC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC2OCCC12)S(=O)(=O)c1ccc2c(c1)CC(=O)N2.COC(OC)N(C)C>>CC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC2OCCC12)S(=O)(=O)c1ccc2c(c1)C(=CN(C)C)C(=O)N2,,ClC(Cl)Cl,,,,test
US20050182040A1,COc1cc(NCc2ccccc2)ccc1C(N)=O>>COc1cc(N)ccc1C(N)=O,[Pd],CCO,,O=C[O-].[NH4+],,test
US04634713,CC(=O)Nc1ccc(NC(=O)NCCCl)cc1>>CC(=O)Nc1ccc(N2CCNC2=O)cc1,,CN(C)C=O,CO,C[O-].[Na+],,test
US20140011795A1,C[C@@H](/N=C1\CCCC1(C)C)c1ccccc1>>C[C@@H](N[C@@H]1CCCC1(C)C)c1ccccc1,,CCO,,Cl,[BH4-].[Na+],test
US05939439,CC(C)(C)OC(=O)NCCOc1cc(Cn2cncc2Cc2ccc(-n3cc(Cl)ccc3=O)nc2)ccc1C#N>>N#Cc1ccc(Cn2cncc2Cc2ccc(-n3cc(Cl)ccc3=O)nc2)cc1OCCN,,CO,,,,test
US20090247567A1,C#CC1CC1.[N-]=[N+]=Nc1nc2c(s1)CCOc1cc(Br)ccc1-2>>Brc1ccc2c(c1)OCCc1sc(-n3nncc3C3CC3)nc1-2,,C1CCOC1,,CC[Mg]Br,,test
US20090227640A1,COC(=O)c1cc(F)ccc1OCC#Cc1ccc(C(F)(F)F)cc1>>O=C(O)c1cc(F)ccc1OCC#Cc1ccc(C(F)(F)F)cc1,,CO,O,[Li+].[OH-],,test
US20070275954A1,Cc1ccc(C2=NC(c3cccs3)C(=O)Nc3ncccc32)cc1.NC1CC1>>Cc1ccc(C2=NC(c3cccs3)C(NC3CC3)=Nc3ncccc32)cc1,,C1CCOC1,,,,test
US20050209213A1,C1CCNC1.Cc1c(N)ccc2cc(C=O)cnc12>>Cc1c(N)ccc2cc(CN3CCCC3)cnc12,,CC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20080070937A1,COc1ccc(S(=O)(=O)Cl)cc1OC.Nc1nc(-c2ccccc2)ns1>>COc1ccc(S(=O)(=O)Nc2nc(-c3ccccc3)ns2)cc1OC,,c1ccncc1,,,,test
US04033975,O=S(Cl)Cl.O=c1oc2cc(Cl)cnc2n1CO>>O=c1oc2cc(Cl)cnc2n1CCl,,CCCCCC,,Cc1ccccc1,O,test
US05763439,CCn1ncc(C#N)c(C#N)c1=O.NCc1ccncc1>>CCn1ncc(NCc2ccncc2)c(C#N)c1=O,,CCO,,,,test
US20140296272A1,CCOC(=O)C(CC1CC1)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1)CCCC3>>Cc1ccc(-c2c(C(CC3CC3)C(=O)O)c(C)nc3sc4c(c23)CCCC4)cc1,,CCO,CO,[Na+].[OH-],,test
US20120277213A1,CN1C(=O)C(C(=O)OCc2ccccc2)CC1(C)C.Clc1ncc(C#Cc2ccccc2)cn1>>CN1C(=O)C(C(=O)OCc2ccccc2)(c2ncc(C#Cc3ccccc3)cn2)CC1(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20160152626A1,CNC(C)(C)C.COc1cc2c(cc1CC(C)C)-c1c(c(C(=O)O)nn1-c1cccs1)CO2>>COc1cc2c(cc1CC(C)C)-c1c(c(C(=O)N(C)C(C)(C)C)nn1-c1cccs1)CO2,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100256363A1,CC(O)(CCO)c1ccccc1.Cc1ccc(S(=O)(=O)Cl)cc1>>Cc1ccc(S(=O)(=O)OCCC(C)(O)c2ccccc2)cc1,,ClCCl,,CCN(CC)CC,O,test
US05346895,CC1(C)CC(C)(C)c2ccc(C#C[Si](C)(C)C)cc2O1>>C#Cc1ccc2c(c1)OC(C)(C)CC2(C)C,,CC(C)O,,[K+].[OH-],,test
US20120040984A1,CCOC(=O)c1ccc(O[C@@H]2CC[C@H](C(=O)OC(C)(C)C)CC2)nc1>>CC(C)(C)OC(=O)[C@@H]1CC[C@H](Oc2ccc(C(=O)O)cn2)CC1,,C1CCOC1,CO,O,[Li+].[OH-],test
US20030181726A1,COc1ccc(C(CC2(O)CCCC2)c2ccc(OC)cc2)cc1.C[Si](C)(C)N=[N+]=[N-]>>COc1ccc(C(CC2(N)CCCC2)c2ccc(OC)cc2)cc1,,c1ccccc1,,CCOCC,FB(F)F,test
US05616579,CCC(=O)Cl.O=C(CSCCO)NC/C=C\COc1cc(CN2CCCCC2)ccn1>>CCC(=O)OCCSCC(=O)NC/C=C\COc1cc(CN2CCCCC2)ccn1,,c1ccncc1,,O=C([O-])O.[Na+],,test
US20110190255A1,CC(C)(C)[Si](C)(C)OS(=O)(=O)C(F)(F)F.CCOC(=O)C[C@H]1CCCN(C[C@@H](O)c2ccc(C#N)cc2)C1>>CCOC(=O)C[C@H]1CCCN(C[C@@H](O[Si](C)(C)C(C)(C)C)c2ccc(C#N)cc2)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05075299,COc1ccc(COc2coc(C)cc2=O)cc1>>Cc1cc(=O)c(O)co1,,COc1ccccc1,,O=C(O)C(F)(F)F,,test
US20060128712A1,CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)O.O=[N+]([O-])c1cccc2sc(N3CCNCC3)nc12>>CC(C)Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2nc3c([N+](=O)[O-])cccc3s2)CC1,,C1CCOC1,,Cl,,test
US04395409,CNC.O=C(Nc1ccccc1)ONC1=Nc2ccc(Cl)cc2C(c2ccccc2)=NC1OC(=O)Oc1ccccc1>>CN(C)C(=O)OC1N=C(c2ccccc2)c2cc(Cl)ccc2N=C1NOC(=O)Nc1ccccc1,,CO,,O,,test
US20140005198A1,Clc1ncnc2cc[nH]c12.OB(O)c1cccnc1F>>Fc1ncccc1-c1ncnc2cc[nH]c12,,CCCCO,O,CC(=O)[O-].[K+],,test
US20100286152A1,CC(C)(C)OC(=O)N1CCNCC1.CC[Al](C#N)CC.O=Cc1cncnc1>>CC(C)(C)OC(=O)N1CCN(C(C#N)c2cncnc2)CC1,,CC(Cl)Cl,O,Cc1ccccc1,O=C([O-])O.[Na+],test
US20050148640A1,CN1CCNCC1.O=C(O)Cc1cccc(OCCCCl)c1>>CN1CCN(CCCOc2cccc(CC(=O)O)c2)CC1,,O,,,,test
US20090143607A1,C=CCC(c1ccccc1)c1ccccc1.C[SiH](C)O[Si](C)(C)C>>C[Si](C)(C)O[Si](C)(C)CCCC(c1ccccc1)c1ccccc1,,CCCCCC,,,,test
US20160222018A1,NCC1CN(Cc2ccccc2)CCN(Cc2ccccc2)CCN1Cc1ccccc1>>NCC1CNCCNCCN1,[Pd],C1CCOC1,,CC(=O)O,O,test
US20110021494A1,CC(=O)OC(C)=O.CCOC(=O)c1nc2c(s1)CNCC2>>CCOC(=O)c1nc2c(s1)CN(C(C)=O)CC2,,ClC(Cl)Cl,,CCN(CC)CC,,test
US04894380,NNC(=O)c1cccnc1.S=C=S>>Sc1nnc(-c2cccnc2)o1,,CCO,O,[K+].[OH-],,test
US20130331372A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COC(=O)[C@@H]1C[C@@H](c2ccc(OC)c(I)c2)C1>>COC(=O)[C@@H]1C[C@@H](c2ccc(OC)c(B3OC(C)(C)C(C)(C)O3)c2)C1,,CS(C)=O,,C1COCCO1,CC(=O)[O-].[K+],test
US20100087427A1,Oc1cccc(N(C[C@H]2CN(Cc3ccccc3)C[C@@H]2Cc2ccccc2)c2ccccc2)c1>>Oc1cccc(N(C[C@H]2CNC[C@@H]2Cc2ccccc2)c2ccccc2)c1,,O,,CC#N,,test
US20070213321A1,CCOC(=O)COc1nc2ccccc2s1>>O=C(O)COc1nc2ccccc2s1,,CO,,Cl,[Na+].[OH-],test
US20120214837A1,CNc1nc2ccc(C)cc2cc1C=O>>CNc1nc2ccc(C)cc2cc1CO,,C1CCOC1,,[BH4-].[Na+],,test
US07179823B1,CCOC(=O)c1cn(Cc2ccc(OCc3ccccc3)cc2)nc1-c1ccccc1>>O=C(O)c1cn(Cc2ccc(OCc3ccccc3)cc2)nc1-c1ccccc1,,CCO,,[K+].[OH-],,test
US20040224974A1,CCOB(OCC)OCC.COc1cc(CO)cc(OC)c1>>COc1cc(CO)cc(OC)c1OB(O)O,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20130059858A1,Brc1ccc2c(c1)CC(C1CCNCC1)O2.CCCS(=O)(=O)Cl>>CCCS(=O)(=O)N1CCC(C2Cc3cc(Br)ccc3O2)CC1,,ClCCl,,CCN(CC)CC,,test
US05393908,CCOC(=O)[C@H](Cc1cc(OC)c(OC)cc1I)NC=O>>CCOC(=O)[C@H](Cc1cc(O)c(O)cc1I)NC=O,,ClCCl,,BrB(Br)Br,,test
US04331666,NC(N)=S.Nc1cc(SCC2=C(C(=O)O)N3C(=O)C(NC(=O)C(=NO)C(=O)CCl)[C@H]3SC2)nn2nnnc12>>Nc1nc(C(=NO)C(=O)NC2C(=O)N3C(C(=O)O)=C(CSc4cc(N)c5nnnn5n4)CS[C@H]23)cs1,,CC(=O)N(C)C,,CCOC(C)=O,,test
US20050009706A1,CCC(CC)/C(O)=C(\C#N)C(=O)OC(C)C.CCN(CC)CC>>CCC(CC)/C(N)=C(\C#N)C(=O)OC(C)C,,ClCCl,,O=P(Cl)(Cl)Cl,,test
US20060276496A1,CC1CNC(=O)c2[nH]c3ccc(C(=O)O)cc3c21.CO>>COC(=O)c1ccc2[nH]c3c(c2c1)C(C)CNC3=O,,Cl,,,,test
US20090221555A1,Clc1ncc(Cl)c(Cl)n1.N[C@@H]1CCCC[C@H]1O>>O[C@@H]1CCCC[C@H]1Nc1nc(Cl)ncc1Cl,,C1CCOC1,,Cl,O=C([O-])[O-].[K+].[K+],test
US20060229312A1,Cc1ccc2c(N3CCN(CCc4cccc([N+](=O)[O-])c4)CC3)c(F)ccc2n1>>Cc1ccc2c(N3CCN(CCc4cccc(N)c4)CC3)c(F)ccc2n1,[Fe],CO,O,[Cl-].[NH4+],,test
US06030984,COCCNc1cc(C)ns1.O=C(O)c1cc(-c2ccc(OCc3ccccc3)cc2)c(=O)n2ccc3ccsc3c12>>COCCN(C(=O)c1cc(-c2ccc(OCc3ccccc3)cc2)c(=O)n2ccc3ccsc3c12)c1cc(C)ns1,,CN(C)C=O,,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US06136823,CCOC(=O)c1cn(-c2cc(NC(=O)OC(C)(C)C)c(F)cc2F)c2c(Cl)c(F)c(F)cc2c1=O.[N-]=[N+]=[N-]>>CCOC(=O)c1cn(-c2cc(NC(=O)OC(C)(C)C)c(F)cc2F)c2c(Cl)c(N=[N+]=[N-])c(F)cc2c1=O,,CCOC(C)=O,,CN(C)C=O,,test
US20030153604A1,CC(C)(C)OC(=O)Nc1ccncc1.II>>CC(C)(C)OC(=O)Nc1ccncc1I,,C1CCOC1,CCOC(C)=O,CN(C)CCN(C)C,[Li]CCCC,test
US20110003807A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.Cc1nn2ccsc2c1-c1nc(-c2ccccc2)c(C(N)=O)s1>>Cc1nn2ccsc2c1-c1nc(-c2ccccc2)c(C(N)=S)s1,,COCCOC,,CCOC(C)=O,Cl,test
US20080021032A1,CN(C)C=O.O=[N+]([O-])c1ccn(CC#CCCl)n1>>O=[N+]([O-])c1ccn(CC#CCO)n1,,CCOC(C)=O,CN(C)C=O,C1CCOC1,Cl,test
US20060211724A1,O=C1c2c(c(O)c3c(ncn3Cc3ccccc3)c2O)C(=O)N1Cc1ccc2c(c1)OCO2>>O=C1c2c(c(O)c3[nH]cnc3c2O)C(=O)N1Cc1ccc2c(c1)OCO2,[Pd],CCN(CC)CC,,CO,,test
US20100022560A1,CCC(CC)c1cc(C)nc2c(-c3sccc3Cl)c(C)nn12.O=C1CCC(=O)N1Br>>CCC(CC)c1cc(C)nc2c(-c3sc(Br)cc3Cl)c(C)nn12,,ClCCl,,,,test
US20100278833A1,COC(=O)c1sc(-n2cnc3nc(OC)ccc32)cc1OCc1ccccc1C(F)(F)F.N>>COc1ccc2c(ncn2-c2cc(OCc3ccccc3C(F)(F)F)c(C(N)=O)s2)n1,,CO,,,,test
US05600047,C#CCCC(CC)(CC)OCOC.CC(=O)C1CCC2C(OC(=O)c3ccccc3)CCCC12C>>CCC(CC)(CCC#CC(C)(O)C1CCC2C(OC(=O)c3ccccc3)CCCC21C)OCOC,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US05700809,C1=C(/C=C/c2ccccc2)CCNC1.CN(C)Cc1c[nH]c2ncccc12>>C1=C(/C=C/c2ccccc2)CCN(Cc2c[nH]c3ncccc23)C1,,Cc1ccccc1,,,,test
US20080255136A1,N#Cc1cccc(N2CC(c3cccc(OCc4ccccc4)c3)CC2=O)c1.OO>>NC(=O)c1cccc(N2CC(c3cccc(OCc4ccccc4)c3)CC2=O)c1,,CCO,,[Na+].[OH-],,test
US20140336106A1,CI.COC(=O)C1CCCC1=O>>COC(=O)C1(C)CCCC1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150274777A1,C[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OC(C)(C)C.O=C(O)C1Cc2ccccc2C1>>C[C@H](NC(=O)C1Cc2ccccc2C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OC(C)(C)C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040248886A1,CC(C)(CN)CO.O=C(NCc1ccc(S(=O)(=O)Cl)s1)c1ccc(Cl)cc1>>CC(C)(CO)CNS(=O)(=O)c1ccc(CNC(=O)c2ccc(Cl)cc2)s1,,CN(C)C=O,,CCN(C(C)C)C(C)C,ClCCl,test
US05143923,CN(CCO)C(=O)c1noc2ccccc12.Fc1ccc2c(C3CCNCC3)noc2c1>>CN(CCC1CCN(c2noc3cc(F)ccc23)CC1)C(=O)c1noc2ccccc12,,C1CCOC1,O,CCN(CC)CC,CS(=O)(=O)Cl,test
US20110275655A1,CC(C)(C)OC(=O)N[C@H]1COCC[C@H]1N=[N+]=[N-]>>CC(C)(C)OC(=O)N[C@H]1COCC[C@H]1N,O=[Pt],,,,,test
US20040225111A1,CCOC(=O)CCCOc1ccc(C[C@H](Nc2nc3cc(OC)ccc3[nH]2)C(=O)OC(C)(C)C)cc1.NC1=NCCCN1>>COc1ccc2[nH]c(N[C@@H](Cc3ccc(OCCCC(=O)NC4=NCCCN4)cc3)C(=O)OC(C)(C)C)nc2c1,,ClCCl,,,,test
US20100075948A1,CC(C)(CCO)CCO[Si](C)(C)C(C)(C)C.CS(=O)(=O)Cl>>CC(C)(CCO[Si](C)(C)C(C)(C)C)CCOS(C)(=O)=O,,ClCCl,,CCN(CC)CC,O,test
US20050014794A1,CI.COc1cccc2c1CC(C(=O)O)CC2>>COC(=O)C1CCc2cccc(OC)c2C1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20050176706A1,CC(C)(CC1(C(F)(F)F)CO1)c1cc(-c2cncnc2)cc2c1OCC2.O=C1CCCc2[nH]ccc21>>CC(C)(CC(O)(Cn1ccc2c1CCCC2=O)C(F)(F)F)c1cc(-c2cncnc2)cc2c1OCC2,,CCO,,C,C[O-].[Na+],test
US20070004675A1,Nc1ccc(Oc2ccnc3cc(C(=O)N4CCCC4)sc23)c(F)c1.O=C(O)CC(=O)Nc1ccccc1>>O=C(CC(=O)Nc1ccc(Oc2ccnc3cc(C(=O)N4CCCC4)sc23)c(F)c1)Nc1ccccc1,,CCOC(C)=O,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
US20110071175A1,CSc1ncc(S(=O)(=O)c2ccccc2)c(Cc2c(C)n(CC(=O)O)c3ccc(F)cc23)n1>>Cc1c(Cc2ncncc2S(=O)(=O)c2ccccc2)c2cc(F)ccc2n1CC(=O)O,[Ni],O,,CCO,,test
US20040157844A1,COc1ccc(Oc2c(C)cc(-n3ncc(=O)[nH]c3=O)cc2Cl)cc1.O=C(O)c1ccc(F)cc1>>COc1ccc(Oc2c(C)cc(-n3ncc(=O)[nH]c3=O)cc2Cl)cc1C(=O)c1ccc(F)cc1,,O,,,,test
US20160244535A1,CC1=Cc2cc3c(cc2C1)CC(C)(C)C3.C[Si](C)(Cl)Cl>>CC1=Cc2cc3c(cc2C1[Si](C)(C)Cl)CC(C)(C)C3,,Cc1ccccc1,,C1CCOC1,[Li]CCCC,test
US20090181957A1,CC(C)(C)[C@H](NC(=O)OCc1ccccc1)c1nn[nH]n1.CI>>Cn1nnc([C@@H](NC(=O)OCc2ccccc2)C(C)(C)C)n1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140039203A1,CNOC.O=C1CC2(CC2)CC(=O)O1>>CON(C)C(=O)CC1(CC(=O)O)CC1,,ClCCl,,Cl,c1ccncc1,test
US06245790B1,O=C(O)c1cccc(C[C@@H]2CCCC=C2c2nc(-c3ccccc3)c(-c3ccccc3)o2)c1>>O=C(O)c1cccc(C[C@@H]2CCCCC2c2nc(-c3ccccc3)c(-c3ccccc3)o2)c1,[Pd],CO,,,,test
US20120214767A1,C=Cc1ccc2c(c1)CCC2=O.NO>>C=Cc1ccc2c(c1)CC/C2=N\O,,CO,,Cl,CC(=O)[O-].[Na+],test
US20150299189A1,CCI.O=[N+]([O-])c1cc(Br)c2[nH]ccc2c1>>CCn1ccc2cc([N+](=O)[O-])cc(Br)c21,,CCOC(C)=O,CN(C)C=O,O,CC(C)(C)[O-].[K+],test
US20050026976A1,O=C1NCc2c(Br)ccc(O)c21.OCCCCl>>O=C1NCc2c(Br)ccc(OCCCCl)c21,,ClCCl,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160164011A1,CCOC(=O)CS.O=C(c1ccccc1)c1scc(Br)c1Br>>CCOC(=O)c1sc2c(Br)csc2c1-c1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080161289A1,N#Cc1ccc(-c2nc3c(s2)CCNCC3)nc1.O=C1CCCC1>>N#Cc1ccc(-c2nc3c(s2)CCN(C2CCCC2)CC3)nc1,CC(=O)O,CO,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090156600A1,Cc1c(Cc2ccc(S(C)(=O)=O)cc2)c(=O)[nH]c2c(Cl)ccc(O)c12.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1c(Cc2ccc(S(C)(=O)=O)cc2)c(=O)[nH]c2c(Cl)ccc(OS(=O)(=O)C(F)(F)F)c12,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20130240784A1,CCCC1CCC(CBr)CC1.CCOc1ccc(Br)cc1F>>CCCC1CCC(c2ccc(Br)cc2F)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090156642A1,O=Cc1cc(-c2cccnc2F)c(Br)s1.Sc1cccc(Br)c1>>O=Cc1cc(-c2cccnc2F)c(Sc2cccc(Br)c2)s1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130338196A1,CC(C)(C)[Si](C)(C)Cl.OC(c1ncco1)C1CCc2ccccc2C1>>CC(C)(C)[Si](C)(C)OC(c1ncco1)C1CCc2ccccc2C1,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US20080113946A1,CS(=O)(=O)c1nc(Cl)c2c(n1)COC2.Cc1cc(N)[nH]n1>>Cc1cc(Nc2nc(S(C)(=O)=O)nc3c2COC3)[nH]n1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20150239870A1,ClCc1ccncc1.O=C(COc1ccc(-c2cc(=O)c3ccccc3o2)cc1)N1CCNCC1>>O=C(COc1ccc(-c2cc(=O)c3ccccc3o2)cc1)N1CCN(Cc2ccncc2)CC1,,Cc1ccccc1,,Cl,O=C([O-])[O-].[K+].[K+],test
US05338740,Brc1cnc2c(c1)CCC2.O=C(OO)c1cccc(Cl)c1>>[O-][n+]1cc(Br)cc2c1CCC2,,ClC(Cl)Cl,,,,test
US05412095,CO.COc1cc2nc(N3CCN(C(=O)C4CCCO4)CC3)nc(N)c2cc1OC.Cl>>COc1cc2nc(N3CCN(C(=O)C4CCCO4)CC3)nc(N)c2cc1OC.C[O-].Cl,,CO,,O,O,test
US20080312226A1,Cn1ncc(Br)c1N.O=C(Cl)OCC(Cl)(Cl)Cl>>Cn1ncc(Br)c1NC(=O)OCC(Cl)(Cl)Cl,,C1CCOC1,,O,c1ccncc1,test
US20120094972A1,CC(C)(C)OC(=O)N1CC2(CCS(=O)(=O)CC2)c2ccc(N3CCOCC3)cc21>>O=S1(=O)CCC2(CC1)CNc1cc(N3CCOCC3)ccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20030065179A1,CC(=O)O[C@H](C)c1nccc(Cl)n1.CN(C)S(=O)(=O)c1ccc2c(c1)CNCC2>>CC(=O)O[C@H](C)c1nccc(N2CCc3ccc(S(=O)(=O)N(C)C)cc3C2)n1,,CC(C)O,,CCN(CC)CC,,test
US20050119320A1,CCN=C=O.Cc1nc(N)sc1-c1ccc(S(C)(=O)=O)c(F)c1>>CCNC(=O)Nc1nc(C)c(-c2ccc(S(C)(=O)=O)c(F)c2)s1,,CN(C)C=O,,,,test
US04820729,CC(=O)C(=O)O.CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N(CC(=O)O)Cc1ccccc1.CCO>>CC(=O)C(=O)O.CC(N[C@H](C(=O)N(CC(=O)O)Cc1ccccc1)C(C)C)C(=O)O,[Pd],CCO,,,,test
US20040048915A1,COC(=O)C(=O)c1cc(C)cc2ccn(C)c12.NC(=O)Cc1c[nH]c2ccccc12>>Cc1cc(C2=C(c3c[nH]c4ccccc34)C(=O)NC2=O)c2c(ccn2C)c1,,CN(C)C=O,,C1CCOC1,CC(C)(C)[O-].[K+],test
US20090131420A1,CN1C(=O)COCC1Cc1ccc(OCc2ccccc2)cc1>>CN1CCOCC1Cc1ccc(OCc2ccccc2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090062223A1,CC(=O)O.CC(C)(C)[SiH2]OC(C)(C)C1OC(n2cc3c(N)cc4c(=O)[nH]ncc(n2)c34)C(C)(O)C1O>>CC(=O)OC1C(C(C)(C)O[SiH2]C(C)(C)C)OC(n2cc3c(N)cc4c(=O)[nH]ncc(n2)c34)C1(C)O,CN(C)c1ccncc1,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20110118238A1,CCn1c(=O)n(C2CCCC2)c2nc(Cl)ncc21.COc1cc(N2CCN(C)CC2)ccc1N>>CCn1c(=O)n(C2CCCC2)c2nc(Nc3ccc(N4CCN(C)CC4)cc3OC)ncc21,,CC(C)O,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04612311,Cc1cc(C)c(S(=O)(=O)NO)c(C)c1.NC1=Nc2ccc(Cl)cc2[SH](=O)(c2ccccc2)N1>>N=C1N[SH](=O)(c2ccccc2)c2cc(Cl)ccc2N1N,,ClCCl,,,,test
US20080004271A1,C[C@@H](COCc1ccccc1)Cc1nc(O)c(C#N)c(-c2ccc(Cl)c(Cl)c2)n1.O=P(Cl)(Cl)Cl>>C[C@@H](COCc1ccccc1)Cc1nc(Cl)c(C#N)c(-c2ccc(Cl)c(Cl)c2)n1,,C1COCCO1,,,,test
US20060052392A1,Cc1cc2c(cc1C)C(=O)OC2=O.Nc1ccc(F)cc1>>Cc1cc2c(cc1C)C(=O)N(c1ccc(F)cc1)C2=O,,CN(C)C=O,,O,,test
US20090082367A1,CC(C)(c1ccc(I)s1)c1nnc(C2CC2)n1C1CC1.N#C[Cu]C#N>>CC(C)(c1ccc(C#N)s1)c1nnc(C2CC2)n1C1CC1,,c1ccncc1,,,,test
US20080299076A1,CCOc1ccccc1-n1c(C(C)N2CCNCC2)nc2cc([N+](=O)[O-])ccc2c1=O.O=C(O)COc1ccc(Cl)cc1>>CCOc1ccccc1-n1c(C(C)N2CCN(C(=O)COc3ccc(Cl)cc3)CC2)nc2cc([N+](=O)[O-])ccc2c1=O,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20050020605A1,CCO/N=C(\c1ccc(Br)cc1)C1CCN(C2(C)CCNCC2)CC1.Cc1nc2ccncc2cc1C(=O)O>>CCO/N=C(\c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3cc4cnccc4nc3C)CC2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100216798A1,O=C1c2ccccc2C(=O)N1Cc1cccc(Nc2ccc3ncc(-c4ccncc4)n3n2)c1>>NCc1cccc(Nc2ccc3ncc(-c4ccncc4)n3n2)c1,,C1CCOC1,CCO,NN,O,test
US04816470,COC(CCCCBr)OC.O=C1NC(=O)c2ccccc21>>COC(CCCCN1C(=O)c2ccccc2C1=O)OC,,CN(C)C=O,,[K],,test
US20150018363A1,Cn1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cc21.OCc1cccs1>>Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4cccs4)cc3=O)cc21,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US04066457,O=C(O)c1cc([N+](=O)[O-])ccc1N1CCCCC1>>Nc1ccc(N2CCCCC2)c(C(=O)O)c1,[Pd],CCO,,,,test
US20100029697A1,CN(C)C=CC(=O)c1ccccc1Cl.N#CCC(N)=O>>N#Cc1ccc(-c2ccccc2Cl)[nH]c1=O,,CN(C)C=O,O,Cl,C[O-].[Na+],test
US20120225061A1,CI.OC1(c2cc(F)cc(F)c2)COC1>>COC1(c2cc(F)cc(F)c2)COC1,,CN(C)C=O,,[H-].[Na+],,test
US20090298878A1,O=S(=O)(c1ccc(Cl)nc1)N1CCC(=NOCc2cccc(C(F)(F)F)c2)CC1.OB(O)c1ccccc1>>O=S(=O)(c1ccc(-c2ccccc2)nc1)N1CCC(=NOCc2cccc(C(F)(F)F)c2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],test
US05324711,OC[C@H](c1ccccc1)n1nnc2ccc(Oc3cc(F)c(C(F)(F)F)c(Cl)c3)cc21>>O=C[C@H](c1ccccc1)n1nnc2ccc(Oc3cc(F)c(C(F)(F)F)c(Cl)c3)cc21,O=[Mn]=O,ClC(Cl)Cl,,,,test
US20150284395A1,CCOC(=O)CC(=O)c1ccc2c(cnn2CC)c1.Nc1[nH]ncc1-c1ncc(-c2ccccc2)o1>>CCn1ncc2cc(-c3cc(=O)n4ncc(-c5ncc(-c6ccccc6)o5)c4[nH]3)ccc21,,CCCCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20050209241A1,O=S(=O)(CCCCl)c1ccc(F)c(F)c1F>>O=S(=O)(c1ccc(F)c(F)c1F)C1CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20100022518A1,CCOC(=O)C(C)Br.Nc1ccc(Cl)c(Cl)c1>>CCOC(=O)C(C)Nc1ccc(Cl)c(Cl)c1,,CCO,,O=C([O-])O.[Na+],,test
US05166398,Cc1cc(C=O)cc(C)c1O.ClCc1ccccc1>>Cc1cc(C=O)cc(C)c1OCc1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110124640A1,CCOC(=O)C(N)=S.Cc1c(C(=N)NN)cccc1[N+](=O)[O-]>>Cc1c(-c2nnc(N)c(=O)[nH]2)cccc1[N+](=O)[O-],,CCO,,,,test
US20120220552A1,CCOC(=O)CN1CCOC(c2ccc(OCc3c(Cl)cccc3Cl)cc2)C1>>O=C(O)CN1CCOC(c2ccc(OCc3c(Cl)cccc3Cl)cc2)C1,,CCO,,Cl,[Na+].[OH-],test
US05424446,CC(=O)[C@@H]1CC(=S)N(C(C)=O)C1>>CC(=O)[C@H]1CNC(=S)C1,,CO,Cl,,,test
US20150118104A1,C=CCBr.C[n+]1cc[nH]c1>>C=CC[n+]1ccn(C)c1.[Br-],,Cc1ccccc1,,,,test
US20090012160A1,CCOC(=O)C(C)(C)CCCCOCCCCC(C)(C)C(=O)O.O=C(Cl)C(=O)Cl>>CCOC(=O)C(C)(C)CCCCOCCCCC(C)(C)C(=O)Cl,,ClCCl,,,,test
US20020055497A1,CC(=O)N1CCc2c(c(-c3ccc(C(F)(F)F)cc3)nn2CC2CO2)C1.CC(C)(C)OC(=O)N1CCC(Oc2noc3ccccc23)CC1>>CC(=O)N1CCc2c(c(-c3ccc(C(F)(F)F)cc3)nn2CC(O)CN2CCC(Oc3noc4ccccc34)CC2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100234429A1,NCc1cccs1.O=C(O)c1cccnc1CCCCc1cccc(C(F)(F)F)c1>>O=C(NCc1cccs1)c1cccnc1CCCCc1cccc(C(F)(F)F)c1,,C1CCOC1,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20020124980A1,CC1(C)CC(O)CC(C)(C)N1O.O=S(=O)(O)O>>CC1(C)CC(O)CC(C)(C)[NH+]1O.O=S(=O)([O-])O,,CC(C)O,,,,test
US20110263647A1,Nc1ccc(Br)cn1.O=C1CCC(=O)N1Cl>>Nc1ncc(Br)cc1Cl,,CCOCC,CN(C)C=O,[Na+].[OH-],,test
US20040235822A1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3)cc1.CS(=O)(=O)OS(C)(=O)=O>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3S(C)(=O)=O)cc1,,C1CCOC1,,O,c1ccncc1,test
US20110312945A1,Cc1cc2c([nH]1)CC(C)(C)CC2=O.Sc1ccccc1>>Cc1[nH]c2c(c1Sc1ccccc1)C(=O)CC(C)(C)C2,,CN(C)C=O,,II,,test
US20070191336A1,CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)n(-c2cccc(CO)c2)n1>>NC(=O)Nc1cccc2ccccc12,,CN(C)C=O,,[H-].[Na+],,test
US20120190686A1,Cc1nccc(NC(=O)C23CCCC(NC(=O)OCc4ccccc4)(CC2)C3)n1>>Cc1nccc(NC(=O)C23CCCC(N)(CC2)C3)n1,,Br,CC(=O)O,,,test
US20060167266A1,CCC#CCO.CS(=O)(=O)c1nsc(-c2cccc(Cl)c2)n1>>CCC#CCOc1nsc(-c2cccc(Cl)c2)n1,,CN(C)C=O,,[H-].[Na+],,test
US20130116270A1,O=C1NCCCC12CCNCC2.O=S(=O)(Cl)c1cc(F)cc(C(F)(F)F)c1>>O=C1NCCCC12CCN(S(=O)(=O)c1cc(F)cc(C(F)(F)F)c1)CC2,,ClCCl,,CCN(CC)CC,Cl,test
US20080009486A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O=C1Nc2cc(Cl)ccc2/C1=C/c1cc(Br)ccc1OCC(F)(F)F>>CC(C)(C)OC(=O)N1C(=O)/C(=C\c2cc(Br)ccc2OCC(F)(F)F)c2ccc(Cl)cc21,CN(C)c1ccncc1,ClCCl,,,,test
US20050203091A1,CC(C)(C)OC(=O)n1nc(I)c2cnc(Oc3ccc(F)cc3F)cc21.OB(O)c1ccccc1Cl>>CC(C)(C)OC(=O)n1nc(-c2ccccc2Cl)c2cnc(Oc3ccc(F)cc3F)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,c1ccccc1,O=C([O-])[O-].[Na+].[Na+],,test
US20120322784A1,CCOC(=O)C1CCN(C(=O)OC(C)(C)C)CC1.Cc1cc(Cl)ncc1Br>>CC(C)(C)OC(=O)N1CCC(C(=O)Cc2cc(Cl)ncc2Br)CC1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20120142677A1,CC(C)(C)OC(=O)CN1CCC[C@H]1C(=O)Nc1cc(C(C)(C)C)no1>>CC(C)(C)c1cc(NC(=O)[C@@H]2CCCN2CC(=O)O)on1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05965619,COC(=O)CC1=C(C)Cc2ccc(OC)cc21.COc1ccc(C=O)c(OC)c1OC>>COc1ccc2c(c1)C(CC(=O)O)=C(C)C2=Cc1ccc(OC)c(OC)c1OC,,O,,C[O-].[Na+],,test
US20110207750A1,N#Cc1ccc(F)c([N+](=O)[O-])c1.Nc1ccc(OC(F)(F)F)cc1>>N#Cc1ccc(Nc2ccc(OC(F)(F)F)cc2)c([N+](=O)[O-])c1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030083361A1,Cc1ccc(-c2cccc(-c3nc4c(ccc5cc(S(=O)(=O)Cl)cc(O)c54)[nH]3)c2)cc1C.Nc1cccc(C(=O)O)c1>>Cc1ccc(-c2cccc(-c3nc4c(ccc5cc(S(=O)(=O)Nc6cccc(C(=O)O)c6)cc(O)c54)[nH]3)c2)cc1C,,C1CCOC1,O,Cl,,test
US20070032494A1,CC(=O)Nc1cc(Cl)c(Sc2cc(C(C)C)c(=O)[nH]n2)c(Cl)c1>>CC(C)c1cc(Sc2c(Cl)cc(N)cc2Cl)n[nH]c1=O,,CO,O,[Na+].[OH-],,test
US20110086854A1,N#CCc1ccc(Cl)cc1F.O=CCC1CC1>>N#C/C(=C\CC1CC1)c1ccc(Cl)cc1F,,CC(C)O,CCOC(C)=O,[Na+].[OH-],,test
US20040157886A1,Nc1ccc2c(c1)CC(=O)N2.O=C(Cl)CCl>>O=C(CCl)Nc1ccc2c(c1)CC(=O)N2,,O,,,,test
US20070066624A1,Cc1nc(Oc2ccc(C#N)cc2)ccc1CN1CCC(N2C(=O)OC[C@H]2c2ccccc2)CC1.[N-]=[N+]=[N-]>>Cc1nc(Oc2ccc(-c3nn[nH]n3)cc2)ccc1CN1CCC(N2C(=O)OC[C@H]2c2ccccc2)CC1,,CN(C)C=O,,[Cl-].[NH4+],,test
US20030195219A1,CCC(=O)Cl.O=[N+]([O-])c1ccc(CCNCCN2CCN(c3ccccc3)CC2)cc1>>CCC(=O)N(CCc1ccc([N+](=O)[O-])cc1)CCN1CCN(c2ccccc2)CC1,,ClCCl,,CCN(CC)CC,,test
US07981919B2,O=C1c2ccsc2C2CN(Cc3ccccc3)CC12>>OC1c2ccsc2C2CN(Cc3ccccc3)CC12,,CO,,[BH4-].[Na+],,test
US05455356,CCOc1ccc([Si]2(CI)CCCC2)cc1.c1nc[nH]n1>>CCOc1ccc([Si]2(Cn3cncn3)CCCC2)cc1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US04590205,COc1ccc(-c2ccsc2-c2ccc(OC)cc2)cc1.O=C1CCC(=O)N1Cl>>COc1ccc(-c2cc(Cl)sc2-c2ccc(OC)cc2)cc1,,CC(=O)O,ClCCl,,,test
US20160000760A1,CC(C)(C)OC(=O)N1CCCC(CS(=O)(=O)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)C1.Nc1cc(Cl)c(Br)c(C(F)(F)F)c1>>CC(C)(C)OC(=O)N1CCCC(CS(=O)(=O)c2ccc(-c3c(Cl)cc(N)cc3C(F)(F)F)cc2)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O,O=C([O-])[O-].[Na+].[Na+],test
US20040063944A1,Clc1ccc(C2(c3ccc4nccc(CCc5ccccc5)c4c3)OCCO2)cc1>>O=C(c1ccc(Cl)cc1)c1ccc2nccc(CCc3ccccc3)c2c1,,CO,Cl,[NH4+].[OH-],,test
US20050261242A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1c(Br)cc(Br)cc1CNC1CCC(O)CC1>>CC(C)(C)OC(=O)Nc1c(Br)cc(Br)cc1CNC1CCC(O)CC1,,C1COCCO1,O,CCN(CC)CC,,test
US20070155721A1,CCOC(=O)c1cc2c(Oc3ccc(C)cc3N)cccc2[nH]1>>CCOC(=O)c1cc2c(Oc3ccc(C)cc3)cccc2[nH]1,,CCOCC,CN(C)C=O,CC(C)(C)ON=O,,test
US20060041137A1,CCCC1=NNC(=O)/C1=C1/C=C(Sc2ccc(N)cc2)c2ccccc2N1.O=C(Cl)c1ccco1>>CCCC1=NNC(=O)/C1=C1/C=C(Sc2ccc(NC(=O)c3ccco3)cc2)c2ccccc2N1,,C1CCOC1,,,,test
US20090149501A1,CN(C)CCO.CS(=O)(=O)Cl>>CN(C)CCOS(C)(=O)=O,,C1CCOC1,,CCN(CC)CC,,test
US06048864,COc1cc2nc(N3CCCN(C(=O)N4CCOCC4)CC3)cc(N)c2cc1OCc1ccccc1>>COc1cc2nc(N3CCCN(C(=O)N4CCOCC4)CC3)cc(N)c2cc1O,[Pd],CCO,,,,test
US20030166639A1,Cc1cc(-c2cccc(C(=O)CC(=O)OC(C)(C)C)c2)ccn1.Nc1cc(Cl)c(Cl)cc1N>>Cc1cc(-c2cccc(C3=Nc4cc(Cl)c(Cl)cc4NC(=O)C3)c2)ccn1,,Cc1ccccc1C,,,,test
US20090325988A1,C#CCC(CC(C)(C)c1ccccc1C(=O)O)(O[Si](C)(C)C)C(F)(F)F.c1ccncc1>>C#CCC(CC(C)(C)c1ccccc1C(N)=O)(O[Si](C)(C)C)C(F)(F)F,,ClCCl,,O=S(Cl)Cl,,test
US20060035938A1,Cc1ccc(C#N)c(=O)n1-c1ccccc1.O=S(=O)(O)O>>Cc1ccc(C(=O)O)c(=O)n1-c1ccccc1,,O=S(=O)(O)O,,O,[Na+].[OH-],test
US20150133428A1,CC(=O)c1ccc(F)c(Cl)c1.CCOC(=O)C(OCC)OCC>>CCOC(OCC)/C(O)=C/C(=O)c1ccc(F)c(Cl)c1,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20050245568A1,CCOC(=O)CC1(CO)CC1.CS(=O)(=O)Cl>>CCOC(=O)CC1(COS(C)(=O)=O)CC1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20120207703A1,COc1cc(Cl)nc(C(N)=O)c1.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COc1cc(Cl)nc(C(N)=S)c1,,C1CCOC1,,,,test
US20050234083A1,CN(c1ccc2c(c1)nc(N)n2C)c1ccnc(Nc2ccc(CS(C)(=O)=O)cc2)n1.Nc1ccccc1.O=C(n1ccnc1)n1ccnc1>>CN(c1ccc2c(c1)nc(NC(=O)Nc1ccccc1)n2C)c1ccnc(Nc2ccc(CS(C)(=O)=O)cc2)n1,,CC(=O)N(C)C,,,,test
US20080319005A1,N#Cc1ccc(-c2ccc(N)cc2C(F)(F)F)cc1.O=C(O)Cc1ccc(-n2cnc3ccccc32)cc1>>N#Cc1ccc(-c2ccc(NC(=O)Cc3ccc(-n4cnc5ccccc54)cc3)cc2C(F)(F)F)cc1,,CO,ClCCl,,,test
US20090275567A1,CC(=O)OC(C)=O.Cc1ncc(-c2ccnc(NC3CCNCC3)n2)n1C(C)C>>CC(=O)N1CCC(Nc2nccc(-c3cnc(C)n3C(C)C)n2)CC1,,ClCCl,,,,test
US05516774,O=C(c1ccc([N+](=O)[O-])cc1Cl)N1Cc2ccnn2Cc2ccccc21>>Nc1ccc(C(=O)N2Cc3ccnn3Cc3ccccc32)c(Cl)c1,,CCO,,CC(=O)O,O=C([O-])O.[Na+],test
US04999378,Clc1ccc(I)cc1.Nc1ccc(Cl)cc1>>Clc1ccc(Nc2ccc(Cl)cc2)cc1,,CS(C)=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20080153799A1,CCN(CC)CC.CCc1c(CO)cccc1Nc1c(C(N)=O)cnc2cc(OCCCNC(C)C)c(OC)cc12.CN1CCCC1=O>>CCc1c(CO)cccc1Nc1c(C(N)=O)cnc2cc(OCCCN(C(=O)C(C)C)C(C)C)c(OC)cc12,,O,,,,test
US20080004297A1,COc1ccc(N(C)c2nc(Cl)nc3ccccc23)cc1.NCc1ccccc1>>COc1ccc(N(C)c2nc(NCc3ccccc3)nc3ccccc23)cc1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US05840732,CCCC=O.O=C1CNC(=O)N1CCCCSc1cccc2nccn12>>CCCC=C1NC(=O)N(CCCCSc2cccc3nccn23)C1=O,,CCO,,C1CCNC1,,test
US20110269769A1,CCn1ccc(-c2nc(-c3ccc(C#N)cc3)c(Sc3ccc(Cl)cc3)n2C)n1.NO>>CCn1ccc(-c2nc(-c3ccc(C(N)=NO)cc3)c(Sc3ccc(Cl)cc3)n2C)n1,,CCO,,CC(=O)N(C)C,,test
US20120058984A1,CS(=O)c1nc(CN2CCOCC2)cc(Nc2nc3ccc([N+](=O)[O-])cc3s2)n1.N[C@H]1CC[C@H](O)CC1>>O=[N+]([O-])c1ccc2nc(Nc3cc(CN4CCOCC4)nc(N[C@@H]4CC[C@@H](O)CC4)n3)sc2c1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20160221972A1,COC(=O)c1ccc2c(c1)O[C@@H](C)CN(c1ccccc1)C2.NO>>C[C@H]1CN(c2ccccc2)Cc2ccc(C(=O)NO)cc2O1,,C1CCOC1,CO,[Na+].[OH-],,test
US20140080798A1,CC(C)(C)OC(=O)N1CC=C(c2ccc([N+](=O)[O-])cc2F)CC1>>CC(C)(C)OC(=O)N1CCC(c2ccc(N)cc2F)CC1,[Pd],CCOC(C)=O,,,,test
US20100113801A1,C1COCCN1.COC(=O)[C@@H]1CCC(=O)N1>>O=C1CCC(C(=O)N2CCOCC2)N1,,Cc1ccccc1C,,,,test
US20060135578A1,CCOc1cc(CCl)ccc1OCc1nc(-c2ccco2)oc1C.O=Cc1cn(-c2ccccc2)nc1O>>CCOc1cc(COc2nn(-c3ccccc3)cc2C=O)ccc1OCc1nc(-c2ccco2)oc1C,,O,,CN(C)C=O,[H-].[Na+],test
US06329381B1,BrBr.Nc1nc(NCCc2ccccc2)nc2c1ncn2Cc1ccccc1>>Nc1nc(NCCc2ccccc2)nc2c1nc(Br)n2Cc1ccccc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US20150376179A1,COC1(c2nccn2C)CCN(C(=O)OC(C)(C)C)CC1>>COC1(c2nccn2C)CCNCC1,,C1COCCO1,,,,test
US20140378493A1,CN(C)c1ncc(Br)c(CO)n1>>CN(C)c1ncc(Br)c(C=O)n1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20160083365A1,Clc1ccnc(Cl)n1.NC1CC1>>Clc1nccc(NC2CC2)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090253689A1,CC(C)(C)S(=O)/N=C/c1cc2nccn2cc1-c1ccc(Cl)cc1Cl.C[Mg]Br>>CC(NS(=O)C(C)(C)C)c1cc2nccn2cc1-c1ccc(Cl)cc1Cl,,C1CCOC1,O,[Cl-].[NH4+],,test
US20070179185A1,CCCN1CC=C(c2cccc(F)c2F)CC1>>CCCN1CCC(c2cccc(F)c2F)CC1,[Pd],CO,,Cl,,test
US20150175600A1,COc1cc(C(=O)N2CCC[C@@H](NC(=O)OC(C)(C)C)C2)cc2nc(-c3cc4cccnc4n3CC(F)(F)F)n(C)c12>>COc1cc(C(=O)N2CCC[C@@H](N)C2)cc2nc(-c3cc4cccnc4n3CC(F)(F)F)n(C)c12,,CO,ClCCl,O=C(O)C(F)(F)F,,test
US20050107419A1,CCN=C=NCCCN(C)C.CCOC(=O)c1c(CCc2ccc(F)cc2)nc2c(c1-c1ccc(C(=O)O)s1)C(=O)N1CCC[C@@H]21.On1nnc2ccccc21>>CCOC(=O)c1c(CCc2ccc(F)cc2)nc2c(c1-c1ccc(C(=O)N[C@@H]3CCc4ccccc43)s1)C(=O)N1CCC[C@@H]21,,ClCCl,,Cl,,test
US20090124802A1,Cc1cc(C)c(Sc2nc(Nc3ccc(C#N)cc3)nc3c2ccn3Cc2ccccc2)c(C)c1>>Cc1cc(C)c(Sc2nc(Nc3ccc(C#N)cc3)nc3[nH]ccc23)c(C)c1,,Clc1ccccc1Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20090163552A1,CCOC(=O)c1ccc(NC(=O)C(C2CCCCC2)n2c(-c3ccc(Cl)cc3)nc3cc(F)c(F)cc32)cc1.COC(=O)c1ccc(N)c(F)c1>>COC(=O)c1ccc(NC(=O)C(C2CCCCC2)n2c(-c3ccc(Cl)cc3)nc3cc(F)c(F)cc32)c(F)c1,CN(C)c1ccncc1,,,,,test
US20100267712A1,CC(C)c1ccc(N)nc1.CCOC(=O)c1cc(OC)ccc1CBr>>COc1ccc2c(c1)C(=O)N(c1ccc(C(C)C)cn1)C2,,CCO,,C,C[O-].[Na+],test
US20050256201A1,CC(C)N.CC1(C)OCc2cc([C@@H]3CN(CCc4ccc(OCCOCc5cccc(C(=O)O)c5)cc4)C(=O)O3)ccc2O1>>CC(C)NC(=O)c1cccc(COCCOc2ccc(CCN3C[C@@H](c4ccc5c(c4)COC(C)(C)O5)OC3=O)cc2)c1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080021056A1,CC(CC(=O)OC(C)(C)C)Nc1ccccc1.O=S(=O)(Cl)c1ccccn1>>CC(CC(=O)OC(C)(C)C)N(c1ccccc1)S(=O)(=O)c1ccccn1,,c1ccncc1,,,,test
US20110005947A1,CCOC(=O)c1cnc(Cl)nc1Cl.Cn1cc(CN)cn1>>CCOC(=O)c1cnc(Cl)nc1NCc1cnn(C)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20040072828A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.O[C@@H](CNC[C@H]1CCc2cc(I)ccc2O1)c1cccnc1>>CC(C)(C)OC(=O)N(C[C@H]1CCc2cc(I)ccc2O1)C[C@H](O)c1cccnc1,,C1CCOC1,,,,test
US20100317659A1,CCOC(=O)c1nc(Nc2cc[nH]n2)c2ccc(I)cc2n1.Fc1ccc([Mg]Br)cc1>>O=C(c1ccc(F)cc1)c1nc(Nc2cc[nH]n2)c2ccc(I)cc2n1,,C1CCOC1,,,,test
US20100016279A1,CN(C(=O)OC(C)(C)C)C1CCNCC1.FC(F)(F)c1nnc2ccc(Cl)nn12>>CN(C(=O)OC(C)(C)C)C1CCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,,test
US20110306618A1,CS(=O)(=O)NC1CCC(N)CC1.Clc1nccc(-c2cnc3c(OCc4ccccc4)cccn23)n1>>CS(=O)(=O)NC1CCC(Nc2nccc(-c3cnc4c(OCc5ccccc5)cccn34)n2)CC1,,CN1CCCC1=O,O,,,test
US05434186,BrCCCCCBr.COC(=O)C=Cc1ccccc1O>>COC(=O)/C=C/c1ccccc1OCCCCCBr,,CCOCC,,CC#N,O=C([O-])[O-].[K+].[K+],test
US20060058361A1,Oc1cccc2ccoc12>>Oc1cccc2c1OCC2,[Pd],CCO,,,,test
US08399444B2,CC(C)c1nc2c(n1Cc1ccc(Cl)cc1)C(=O)CCCC2.CCOC(C)=O>>CCOC(=O)CC1(O)CCCCc2nc(C(C)C)n(Cc3ccc(Cl)cc3)c21,,C1CCOC1,,[Cl-].[NH4+],C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US05318939,CC(=O)N(C=CC=C(C#N)C#N)c1ccccc1.CCCCCCNCCCCCC>>CCCCCCN(C=CC=C(C#N)C#N)CCCCCC,,CCO,,,,test
US20080039452A1,CCOC(=O)c1ccc(N(C)CCOC)cc1>>COCCN(C)c1ccc(C(=O)O)cc1,,CO,,[Na+].[OH-],,test
US04659516,CCCCN(C)C(=O)CCCCCCCCCC[C@@H]1Cc2cc(O)ccc2[C@H]2CC[C@@]3(C)[C@@H](CC[C@@H]3O)[C@@H]21.O=C(Cl)c1ccccc1>>CCCCN(C)C(=O)CCCCCCCCCC[C@@H]1Cc2cc(OC(=O)c3ccccc3)ccc2[C@H]2CC[C@@]3(C)[C@@H](CC[C@@H]3O)[C@@H]21,,CC(C)=O,,O=C([O-])O.[Na+],,test
US20110034507A1,Nc1cccc(B(O)O)c1.Oc1ccc2cc(Br)ccc2c1>>Nc1cccc(-c2ccc3cc(O)ccc3c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20090176778A1,CS(=O)(=O)Cl.NC1CN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)C1>>CS(=O)(=O)NC1CN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,O,test
US20140010783A1,N#CCc1c(Cl)cc(Nc2n[nH]c(N)n2)cc1C(F)(F)F.[N-]=[N+]=[N-]>>Nc1nc(Nc2cc(Cl)c(Cc3nnn[nH]3)c(C(F)(F)F)c2)n[nH]1,,CN(C)C=O,,[Cl-].[NH4+],,test
US20120046269A1,CC(C)(C)OC(=O)Nc1cccc(CNc2ncnc3c(C(N)=O)cc(CO)cc23)c1.CO.Cl>>CC(Nc1ncnc2c(C(N)=O)cc(Cl)cc12)c1cccc(N)c1,,CO,,C1COCCO1,,test
US20040044000A1,CC(C)(C)OC(=O)c1ccc(CBr)cc1.Oc1nccc2ccc(Br)cc12>>CC(C)(C)OC(=O)c1ccc(Cn2ccc3ccc(Br)cc3c2=O)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130267541A1,C[C@H]1NC(=S)[C@@H](NC(=O)OC(C)(C)C)C[C@H]1c1ccccc1.NCC(O)CC(F)(F)F>>C[C@H]1NC(=NCC(O)CC(F)(F)F)[C@@H](NC(=O)OC(C)(C)C)C[C@H]1c1ccccc1,Cl[Hg]Cl,CCO,,CCN(CC)CC,Cl,test
US20090176847A1,CCOC1CC2CC(NCC(=O)N3CCCC3C#N)CC2C1.Cl>>CCOC1CC2CC(NCC(=O)N3CCCC3C#N)CC2C1.Cl,,CCOCC,,,,test
US20060287343A1,CN1CC=C(c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)CC1>>CN1CC=C(c2cc3nccc(Oc4ccc(N)cc4F)c3s2)CC1,[Fe],CCO,,O,[Cl-].[NH4+],test
US05536718,CCN(C(C)C)C(C)C.COC(=O)c1ccc(N)nc1.Cc1ccccc1CC(=O)Cl.ClCCl.O>>COC(=O)c1ccc(N(C(=O)Cc2ccccc2C)C(=O)Cc2ccccc2C)nc1,,ClCCl,O,,,test
US20130217699A1,O=C(Cl)C(=O)Cl.O=C(O)c1sc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2c1CCCC2>>O=C(Cl)c1sc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2c1CCCC2,CN(C)C=O,,,,,test
US20120323006A1,COC(=O)[C@@H](N)CNC(=O)OC(C)(C)C.FC(F)(F)c1ccc(CN(CCCl)CCCl)cc1>>COC(=O)[C@H](CNC(=O)OC(C)(C)C)N1CCN(Cc2ccc(C(F)(F)F)cc2)CC1,,CCN(C(C)C)C(C)C,,Cl,,test
US20130225588A1,COC(=O)Cc1cc2ccc(F)cc2c(-c2ccc(S(C)(=O)=O)cc2)c1C>>Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(C)(=O)=O)cc1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20040063698A1,COC(=O)C(C)C(O)c1ccc(O)cc1.Cc1cc(CCl)c2ccccc2n1>>COC(=O)C(C)C(O)c1ccc(OCc2cc(C)nc3ccccc23)cc1,,CS(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20160108027A1,CC1OC[C@H]([C@@H](C)O)N(Cc2ccccc2)C1=O>>CC1CN(Cc2ccccc2)[C@@H]([C@@H](C)O)CO1,,C1CCOC1,,CO,,test
US04745115,N#CCc1ccc2ccccc2c1Cl.O=Cc1ccccc1Cl>>O=C1Cc2c(cc3ccccc3c2Cl)C(c2ccccc2Cl)N1,,O,,[NH4+].[OH-],,test
US06559162B2,CNC1C2CCC1CN(Cc1ccccc1)C2.Cc1ccc(S(=O)(=O)OCCCNc2ccc(C#N)cc2)cc1>>CN(CCCNc1ccc(C#N)cc1)C1C2CCC1CNC2,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120329785A1,COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1.Nc1ccc(C(=O)N2CCCC2)cc1>>COc1ccc2nc(Nc3ccc(C(=O)N4CCCC4)cc3)c3n[nH]cc3c2c1,C1COCCO1,CO,,Cl,,test
US20100137587A1,COC(=O)[C@@H]1C[C@H](N(CC(C)C)C(=O)c2nc3c(Cl)cccc3[nH]2)CN(C(=O)OC(C)(C)C)C1.COCCCCOS(C)(=O)=O>>COCCCCn1c(C(=O)N(CC(C)C)[C@H]2C[C@@H](C(=O)OC)CN(C(=O)OC(C)(C)C)C2)nc2cccc(Cl)c21,,CC(=O)N(C)C,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050148631A1,Cc1cccc(NS(=O)(=O)c2ccc(Br)cc2)n1.OB(O)c1ccc(Cl)cc1>>Cc1cccc(NS(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20050032829A1,CCCc1nc2c(c(C)c(C)n3nnnc23)n1CC(C)(C)N.CS(=O)(=O)Cl>>CCCc1nc2c(c(C)c(C)n3nnnc23)n1CC(C)(C)NS(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US05684011,Cc1ccc(S(=O)(=O)OCCC=C(F)F)cc1.NC(N)=S>>Cc1ccc(S(=O)(=O)O)cc1.NC(=S)NCCC=C(F)F,,CCO,,,,test
US20140336165A1,Clc1ccc(/C=C/c2cc(OCc3ccccc3)c(OCc3ccccc3)nn2)cc1>>Clc1ccc(CCc2cc(OCc3ccccc3)c(OCc3ccccc3)nn2)cc1,,ClCCl,,CCN(CC)CC,O,test
US20130178478A1,CCOC(=O)c1nnc(Cl)cc1Nc1cccc(CC)n1.N>>CCc1cccc(Nc2cc(Cl)nnc2C(N)=O)n1,,CO,,,,test
US20080312226A1,CCOc1ncncc1NC(=O)OCC(Cl)(Cl)Cl.c1ccc(-c2csc(N3CCNCC3)n2)cc1>>CCOc1ncncc1NC(=O)N1CCN(c2nc(-c3ccccc3)cs2)CC1,,O,,CCN(C(C)C)C(C)C,CS(C)=O,test
US20050014811A1,Nc1nc2ccc(OS(=O)(=O)c3ccc(NC4CCCC4)cc3)cc2[nH]1.O=C(O)CCc1ccccc1>>O=C(CCc1ccccc1)Nc1nc2cc(OS(=O)(=O)c3ccc(NC4CCCC4)cc3)ccc2[nH]1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20140094473A1,CC(C)(C)C(CC(N)=NO)Nc1nc(-c2c[nH]c3ncc(F)cc23)ncc1F.O=C(c1ncc[nH]1)c1ncc[nH]1>>CC(C)(C)C(Cc1nc(=O)o[nH]1)Nc1nc(-c2c[nH]c3ncc(F)cc23)ncc1F,,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,[Cl-].[NH4+],test
US05328927,CC(=O)NC(Cc1csc2ccccc12)C(=O)C=Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1>>CC(=O)NC(Cc1csc2ccccc12)C(=O)CCc1cc(C(F)(F)F)cc(C(F)(F)F)c1,[Pd],C1CCOC1,,,,test
US20030181466A1,CCOC(=O)C(Cl)=NNc1ccc(OC)cc1.O=C1CCCCN1c1ccc(N2CCC=C(N3CCOCC3)C2=O)cc1>>CCOC(=O)c1nn(-c2ccc(OC)cc2)c2c1CCN(c1ccc(N3CCCCC3=O)cc1)C2=O,,CCOC(C)=O,O,CCN(CC)CC,Cl,test
US20100298336A1,CC(C)c1nccc(Cl)c1C(=O)[O-]>>CC(C)c1nccc(Cl)c1CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040009995A1,CC(C)(C)OC(=O)CBr.Cc1ccc(CO)cc1I>>Cc1ccc(COCC(=O)OC(C)(C)C)cc1I,,CN(C)C=O,,[H-].[Na+],,test
US20060189636A1,CCc1ncnc2c1ncn2[C@@H]1O[C@H](COS(=O)(=O)NC(c2ccccc2)(c2ccccc2)c2ccccc2)[C@H]2OC(C)(C)O[C@H]21>>CCc1ncnc2c1ncn2[C@@H]1O[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]1O,,O,O=C(O)C(F)(F)F,,,test
US20020137782A1,CCOC(=O)Cc1ccc(N)c(O)c1.Cc1ccccc1N=C=S>>Cc1ccccc1Nc1nc2ccc(CC(=O)O)cc2o1,,CCO,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20160229814A1,CC1CC(=O)OC(=O)C1.CCn1c(=O)c2nc(N)cnc2n(CC)c1=O>>CCn1c(=O)c2nc(NC(=O)CC(C)CC(=O)O)cnc2n(CC)c1=O,,Cc1ccccc1,,,,test
US20100273806A1,CCO.CCOC(=O)CC1CCc2c1[nH]c1ccc(-c3noc(-c4ccc(F)c(C#N)c4)n3)cc21>>CCOc1ccc(-c2nc(-c3ccc4[nH]c5c(c4c3)CCC5CC(=O)O)no2)cc1C#N,,C1CCOC1,O,[Na+].[OH-],,test
US20050080096A1,C=O.O=c1[nH]c(CCCN2CC=C(c3ccccc3)CC2)nc2c1CNCC2>>CN1CCc2nc(CCCN3CC=C(c4ccccc4)CC3)[nH]c(=O)c2C1,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100125081A1,C=CCBr.Cc1cccc(Br)c1O>>C=CCOc1c(C)cccc1Br,,CN(C)C=O,,O,[H-].[Na+],test
US20140163012A1,CC(C)(C)OC(=O)N1CCc2oc3cc(-n4ccc(CCc5ccc(Cl)cn5)cc4=O)ccc3c2C1>>O=c1cc(CCc2ccc(Cl)cn2)ccn1-c1ccc2c3c(oc2c1)CCNC3,,CCOCC,CO,Cl,,test
US20160000760A1,CN(C)S(=O)(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1.Nc1nc(Nc2cc(F)c(Br)c(Cl)c2)n[nH]1>>CN(C)S(=O)(=O)c1ccc(-c2c(F)cc(Nc3n[nH]c(N)n3)cc2Cl)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[Na+].[Na+],,test
US20110212998A1,CO.O=C(O)c1cnc(Cl)c(Cl)c1>>COc1ncc(C(=O)O)cc1Cl,,O,,,,test
US20080096860A1,CC(C)(C)OC(=O)N[C@@H]1CCNC1.NS(N)(=O)=O>>CC(C)(C)OC(=O)N[C@@H]1CCN(S(N)(=O)=O)C1,,C1COCCO1,,,,test
US20050038246A1,CO.O=C(O)CCc1c[nH]c2ccc(Br)cc12>>COC(=O)CCc1c[nH]c2ccc(Br)cc12,,CO,,C[Si](C)(C)Cl,,test
US20110009395A1,C=CC[Mg]Br.O=Cc1cccc(Br)c1>>C=CCC(O)c1cccc(Br)c1,,CCOCC,CCOCC,,,test
US20060194816A1,CC(=O)Nc1cccc(B(O)O)c1.O=C(c1ccc(Cl)cc1Cl)c1oc2cc(OS(=O)(=O)C(F)(F)F)ccc2c1C(F)(F)F>>CC(=O)Nc1cccc(-c2ccc3c(C(F)(F)F)c(C(=O)c4ccc(Cl)cc4Cl)oc3c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100137338A1,Cn1nccc1-c1ccc(C(=O)N[C@@H](Cc2ccccc2C(F)(F)F)CN2C(=O)c3ccccc3C2=O)cc1Br>>Cn1nccc1-c1ccc(C(=O)N[C@H](CN)Cc2ccccc2C(F)(F)F)cc1Br,,C1CCOC1,CO,NN,,test
US08129371B2,CNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3cnn(C4CCC(=O)CC4)c3n2)cc1.CO.COC(OC)OC>>CNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3cnn(C4CCC(OC)(OC)CC4)c3n2)cc1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090048320A1,CCN(CC)S(F)(F)F.CCOP(OCC)C(O)c1cccc(Br)c1>>CCOP(OCC)C(F)c1cccc(Br)c1,,O,,ClCCl,,test
US20090131414A1,C1COCCN1.Fc1ccc(-c2ccc3ncnc(Cl)c3n2)cc1>>Fc1ccc(-c2ccc3ncnc(N4CCOCC4)c3n2)cc1,,C1COCCO1,,,,test
US20090118259A1,COC(=O)c1ccc2c(c1)ncn2CCC#N>>N#CCCn1cnc2cc(C(=O)O)ccc21,,C1CCOC1,O,CO,[Li+].[OH-],test
US20150239866A1,C=C(CCl)CCl.C=O.CCOC(C)=O>>ClCC1(CCl)CCOCO1,,ClCCCl,,O=S(=O)(O)O,,test
US07012089B2,CN1CCc2c(Cl)ccc3c4c(n(c23)CC1)CCCC4>>Clc1ccc2c3c(n4c2c1CCNCC4)CCCC3,,CC(Cl)Cl,,CC(Cl)OC(=O)Cl,,test
US20120190675A1,CC1(C)COC2(CCC(O)(CC(O)CO)CC2)OC1>>CC1(C)COC2(CCC(O)(CC=O)CC2)OC1,,ClCCl,,O,,test
US04520007,CCC(C)OC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1>>CCC(C)OC(=O)C=Cc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1,,ClCCl,,,,test
US05462940,Cl.O=C1CN(N=Cc2ccc(-c3ccc(Cl)cc3)o2)C(=O)N1CCCCl.OCCN1CCNCC1>>Cl.Cl.O=C1CN(N=Cc2ccc(-c3ccc(Cl)cc3)o2)C(=O)N1CCCN1CCN(CCO)CC1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20110312930A1,Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1ccc(CCCO)nc1>>Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)cc3)no2)nn1Cc1ccc(CCC=O)nc1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=C([O-])O.[Na+],test
US20090197862A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1cc2cc(F)ccc2cn1>>O=S(=O)(Oc1cc2cc(F)ccc2cn1)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20070129346A1,CC(C)C(=O)N(C1CCCCC1)[C@H]1CCN(NC(=O)[C@@H](Cc2ccc(Cl)cc2)NC[C@H]2CCCN2C(=O)OC(C)(C)C)C1>>CC(C)C(=O)N(C1CCCCC1)[C@H]1CCN(NC(=O)[C@@H](Cc2ccc(Cl)cc2)NC[C@H]2CCCN2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080015208A1,CC(C)(C)OC(=O)NCC1CCCc2cc(NS(=O)(=O)c3cccc(F)c3)ccc21.CI>>CN(c1ccc2c(c1)CCCC2CN)S(=O)(=O)c1cccc(F)c1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130085128A1,CC(C)(C)OC(=O)NC1(c2ccccc2)CCNCC1.Cc1nn(C2CCCCO2)c2nc(-c3ccc(OCc4ccccc4)cc3F)cc(C(=O)O)c12>>Cc1nn(C2CCCCO2)c2nc(-c3ccc(OCc4ccccc4)cc3F)cc(C(=O)N3CCC(NC(=O)OC(C)(C)C)(c4ccccc4)CC3)c12,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090042929A1,BrCC1CCCCC1.O=C(NCc1cccs1)C12CC3CC(CC(C3)C1)C2>>O=C(N(Cc1cccs1)CC1CCCCC1)C12CC3CC(CC(C3)C1)C2,,CN(C)C=O,,[H-].[Na+],,test
US20150126449A1,Cc1ccnc2nn3c(C4CCN(C(=O)OC(C)(C)C)CC4)cc(=O)[nH]c3c12.Cl>>Cc1ccnc2nn3c(C4CCNCC4)cc(=O)[nH]c3c12.Cl,,C1COCCO1,CO,,,test
US20060241147A1,CC(C)(C)OC(=O)N1CCC(C(=O)Nc2ccc(Oc3ccc4c(c3)CCC(c3ccccc3)O4)nc2)CC1>>O=C(Nc1ccc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)nc1)C1CCNCC1,,CCOCC,,Cl,,test
US20110136802A1,COc1cc(O)c2c(c1)SC[C@H]1[C@@]2(C)CC[C@H]2C(C)(C)CCC[C@@]21C.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1cc(OS(=O)(=O)C(F)(F)F)c2c(c1)SC[C@H]1[C@@]2(C)CC[C@H]2C(C)(C)CCC[C@@]21C,,ClCCl,,c1ccncc1,,test
US20050054683A1,CC(=O)NC[C@H]1CN(c2ccc(C3CNC3)c(F)c2)C(=O)O1.O=Cn1nnc2ccccc21>>CC(=O)NC[C@H]1CN(c2ccc(C3CN(C=O)C3)c(F)c2)C(=O)O1,,C1CCOC1,,,,test
US20160060229A1,C=CCC1(N(O)C(=O)OC(C)(C)C)C(=O)NC(=O)NC1=O>>C=CCC1(NO)C(=O)NC(=O)NC1=O,,CCO,Cl,,,test
US06995184B2,C=CC#N.Cc1cc2cccc(Cl)c2[nH]1>>Cc1cc2cccc(Cl)c2n1CCC#N,,C1COCCO1,,,,test
US20140256719A1,Clc1nc(Cl)c2c(-c3ccccc3)ccn2n1.c1cnc2c(c1)CNC2>>Clc1nc(N2Cc3cccnc3C2)c2c(-c3ccccc3)ccn2n1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20110312905A1,O=[N+]([O-])c1ccc(S(=O)(=O)Cl)c([N+](=O)[O-])c1.O=c1cccccc1O>>O=c1cccccc1OS(=O)(=O)c1ccc([N+](=O)[O-])cc1[N+](=O)[O-],,c1ccncc1,,,,test
US20120083475A1,CCOC(=O)C(N)=NO.O=C(Cl)Cc1ccc(F)cc1>>CCOC(=O)c1noc(Cc2ccc(F)cc2)n1,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US20130116243A1,CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4c(cc3-c3ccccc3)NC(=O)C(CCO)O4)cc2)CCC1.CI>>CN1C(=O)C(CCO)Oc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)cc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04150131,COC(=O)Nc1cc(N2CCCCC2)nc(NC(=O)OC)[n+]1[O-]>>COC(=O)Nc1cc(N2CCCCC2)nc2nc(=O)on12,,O,,ClCCl,[Na+].[OH-],test
US20140163008A1,CCOC(=O)C(F)=C1c2ccc(Br)cc2COc2cc(F)ccc21.N>>NC(=O)C(F)=C1c2ccc(Br)cc2COc2cc(F)ccc21,,C1CCOC1,,CO,,test
US04605674,CCCCCCCCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCCCCCCCC.COc1ccc(C=CC(=O)c2c(O)cc(OC)cc2OC)cc1>>CCCCCCCCCCCCCCCCCC(=O)Oc1cc(OC)cc(OC)c1C(=O)C=Cc1ccc(OC)cc1,,c1ccncc1,,,,test
US05084084,CI.O=C1COc2cc(F)c(-n3c(=O)cc(C(F)(F)F)[nH]c3=O)cc2N1>>Cn1c(C(F)(F)F)cc(=O)n(-c2cc3c(cc2F)OCC(=O)N3)c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020198388A1,CNc1cccc(S(=O)(=O)N(C[C@@H](O)[C@H](Cc2ccccc2)NC(=O)O[C@H]2CO[C@H]3OCC[C@@H]23)CC(C)(C)CCCCN)c1.COC(=O)Cl>>CNc1cccc(S(=O)(=O)N(C[C@@H](O)[C@H](Cc2ccccc2)NC(=O)O[C@H]2CO[C@H]3OCC[C@@H]23)CC(C)(C)CCCCNC(=O)OC)c1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US04138256,COCCI.N#CCCP(CCC#N)c1ccccc1>>COCC[PH+](CCC#N)c1ccccc1.[I-],,CC#N,,,,test
US20130137700A1,ClCCN1CCn2c1nc1ccccc12.Cn1cc(O)c(=O)c(-c2ccnn2-c2ccccc2)n1>>Cn1cc(OCCN2CCn3c2nc2ccccc23)c(=O)c(-c2ccnn2-c2ccccc2)n1,,CC(=O)N(C)C,,[I-].[Na+],O=C([O-])[O-].[Cs+].[Cs+],test
US20130267510A1,CCC1OCc2cccc(Oc3ccc(NC(=O)[C@H](N)CC)cn3)c21.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCC1OCc2cccc(Oc3ccc(N4C(=O)N[C@H](CC)C4=O)cn3)c21,,ClCCl,,,,test
US06936602B1,CCCBr.O=Cc1cccc(O)c1>>CCCOc1cccc(C=O)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070185133A1,CC(C)(C)OC(=O)NCCN.CCOC(=O)CN=C=O.Cl>>Cl.NCCN1C(=O)CNC1=O,,ClCCl,,CCO,,test
US20160096827A1,Cc1cc([N+](=O)[O-])ccc1C1=CCN(C=O)CC1>>Cc1cc(N)ccc1C1CCN(C=O)CC1,[Pd],CO,,[H][H],,test
US07417056B2,CC(C)(CC(O)(C=O)C(F)(F)F)c1cc(F)cc2c1OCC2.Cc1ccc2c(N)cccc2n1>>Cc1ccc2c(N=CC(O)(CC(C)(C)c3cc(F)cc4c3OCC4)C(F)(F)F)cccc2n1,,CC(=O)O,Cc1ccccc1,O,,test
US20100137282A1,CC1(N)CCN(C[C@@H]2CN3C(=O)CCc4ccc(=O)n2c43)CC1.O=C([O-])O>>CC1(N=C=O)CCN(C[C@@H]2CN3C(=O)CCc4ccc(=O)n2c43)CC1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20090306133A1,CN1CCN(c2ccc(-c3cc(C(=O)NC[C@@H]4CC[C@@H](CNC(=O)OC(C)(C)C)CC4)c4ccccc4n3)cn2)CC1>>CN1CCN(c2ccc(-c3cc(C(=O)NC[C@@H]4CC[C@@H](CN)CC4)c4ccccc4n3)cn2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070082912A1,Cc1ccc(-c2cc(C(F)(F)F)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)n1>>Cc1ccc(-c2cc(C(F)(F)F)ccc2O)n1-c1cccc(C(=O)O)n1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20090186879A1,CC[Mg]Br.COc1nc(C)c(N2CCCn3c2nc2c(Cl)ccc(C=O)c23)c(C)n1>>CCC(O)c1ccc(Cl)c2nc3n(c12)CCCN3c1c(C)nc(OC)nc1C,,C1CCOC1,,,,test
US20110021500A1,CCC1Cc2ccc(F)cc2N1.O=C(Cl)c1cc(Cl)ncn1>>CCC1Cc2ccc(F)cc2N1C(=O)c1cc(Cl)ncn1,,ClCCl,,[Na+].[OH-],,test
US20100292421A1,CCC1=CC=CC1.C[Si](C)(Cl)C1C=CC=C1>>CCC1=CC([Si](C)(C)C2C=CC=C2)C=C1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20100298336A1,BrP(Br)Br.OCc1cccnc1F>>Fc1ncccc1CBr,,ClCCl,,,,test
US20050143421A1,CC(=O)NC[C@H]1CN(c2ccc(N3CCC(=O)CC3)c(F)c2)C(=O)O1.N#CCC1CC1>>CC(=O)NC[C@H]1CN(c2ccc(N3CCC(O)(C(C#N)C4CC4)CC3)c(F)c2)C(=O)O1,,C1CCOC1,,[Li]CCCC,,test
US20050101584A1,COc1ccc(N(CCc2cccc(OC)c2)C(C)=O)cc1>>COc1ccc(N2CCc3cc(OC)ccc3C2C)cc1,,O=P(Cl)(Cl)Cl,,[I-].[K+],,test
US06517836B1,C1CN1.O=C(NCC(O)CO)c1cc(Cl)c([N+](=O)[O-])cc1[N+](=O)[O-]>>O=C(NCC(O)CO)c1cc(N2CC2)c([N+](=O)[O-])cc1[N+](=O)[O-],,CCOC(C)=O,,,,test
US20070232583A1,Cc1cc(-c2ccc(Cl)cc2)nc(-n2cnc(-c3cccc(S(=O)(=O)NC(C)(C)C)c3)c2)n1>>Cc1cc(-c2ccc(Cl)cc2)nc(-n2cnc(-c3cccc(S(N)(=O)=O)c3)c2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060270692A1,Clc1ncnc2cc(OCc3ccccc3)ccc12.Nc1cnn(CC(=O)Nc2cccc(F)c2F)c1>>O=C(Cn1cc(Nc2ncnc3cc(OCc4ccccc4)ccc23)cn1)Nc1cccc(F)c1F,,CC(=O)N(C)C,ClCCl,C1COCCO1,Cl,test
US20020042537A1,CC(C)(CCC=O)[N+](=O)[O-].O=C1CNC(=O)N1>>CC(C)(CCC=C1NC(=O)NC1=O)[N+](=O)[O-],,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20110112146A1,COC(=O)C1C(=O)c2ccccc2OC1c1ccc2c(c1)OCO2>>COC(=O)C1C(O)c2ccccc2OC1c1ccc2c(c1)OCO2,,C1CCOC1,CO,O,[BH4-].[Na+],test
US20070249579A1,COc1cnc(Cl)c2[nH]cc(C(=O)C(=O)O)c12.c1ccc(-n2nnnc2N2CCNCC2)cc1>>COc1cnc(Cl)c2[nH]cc(C(=O)C(=O)N3CCN(c4nnnn4-c4ccccc4)CC3)c12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20120277220A1,CC(C)(C)OC(=O)NCCCNc1nc(Cl)ncc1C(=O)O.Fc1nc(F)nc(F)n1>>CC(C)(C)OC(=O)NCCCNc1nc(Cl)ncc1C(=O)F,,ClCCl,,CCN(CC)CC,,test
US20150368210A1,CC(C)(C)OC(=O)[C@H]1CC(N)CCN1C(=O)OC(C)(C)C.Nc1ncc(-c2cccc(C=O)c2)nc1NCc1c(Cl)cccc1Cl>>CC(C)(C)OC(=O)[C@H]1CC(NCc2cccc(-c3cnc(N)c(NCc4c(Cl)cccc4Cl)n3)c2)CCN1C(=O)OC(C)(C)C,,ClCCCl,,ClCCl,O=C([O-])O.[Na+],test
US20070259864A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.OCCNCc1ccccc1>>O=S(=O)(OCCN(Cc1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F,,ClCCl,ClCCl,CCN(C(C)C)C(C)C,,test
US20090099161A1,COCc1nc2c(N)nc3cc(C=CC#N)ccc3c2n1CC(C)(C)O>>COCc1nc2c(N)nc3cc(CCCN)ccc3c2n1CC(C)(C)O,[Pd],CO,,O=C(O)C(F)(F)F,,test
US04250178,COc1nc(N)ncc1C(=O)O.ClP(Cl)(Cl)(Cl)Cl>>COc1nc(N)ncc1C(=O)Cl.Cl,,CCOCC,,,,test
US20140045872A1,CCOC(=O)NCCc1ccccc1Cl>>O=C1NCCc2c(Cl)cccc21,,O=P(Cl)(Cl)Cl,,O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3,,test
US20140275015A1,O=C(Cl)c1cccc(C(F)(F)F)c1Cl.c1ccc(-n2nnc3c2CCNC3)nc1>>O=C(c1cccc(C(F)(F)F)c1Cl)N1CCc2c(nnn2-c2ccccn2)C1,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US20070105842A1,COC(OC)N(C)C.Cc1ccccc1CC(N)=O>>Cc1ccccc1CC(=O)NC=O,,CC(=O)O,,,,test
US20090170873A1,COC(=O)c1cc(-c2ccc(C)cn2)cc(-c2ccnn2CC2CC2)c1>>Cc1ccc(-c2cc(C(=O)O)cc(-c3ccnn3CC3CC3)c2)nc1,,CO,,[Na+].[OH-],,test
US07709479B1,CI.COc1cc2c(=S)[nH]cnc2cc1OCc1ccccc1>>COc1cc2c(SC)ncnc2cc1OCc1ccccc1,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20050203158A1,CCCCNc1cc(C(=O)NC)ccc1[N+](=O)[O-]>>CCCCNc1cc(CNC)ccc1[N+](=O)[O-],,C1CCOC1,,B,Cl,test
US20140296225A1,C=O.Cc1cc(Br)ccc1C(=O)O>>O=C1OCCc2cc(Br)ccc21,,C1CCOC1,,Cl,CC(C)[N-]C(C)C.[Li+],test
US20110028486A1,CCOc1cccc(-c2ccc(C(=O)O)cn2)c1.NCc1ccc2[nH]c(C(F)(F)F)cc2c1>>CCOc1cccc(-c2ccc(C(=O)NCc3ccc4[nH]c(C(F)(F)F)cc4c3)cn2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04430346,Cl.N=C(N)NCCCC[C@H](O)CC(N)=O.O=C(Cl)c1ccccc1>>Cl.N=C(N)NCCCC[C@@H](CC(N)=O)OC(=O)c1ccccc1,,c1ccncc1,,CN(C)C=O,,test
US20070093476A1,BrCCCBr.c1ccc2c(c1)CCCN2>>BrCCCN1CCCc2ccccc21,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],,test
US05240938,Cc1ccc(OC(C#N)c2ccccc2Cl)cc1.O=C1CCC(=O)N1Br>>N#CC(Oc1ccc(CBr)cc1)c1ccccc1Cl,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20090233915A1,CN.COC(=O)C(C)(C)CON1C(=O)c2ccccc2C1=O>>CNC(=O)C(C)(C)CON,,CO,,,,test
US20010049371A1,CCOc1cc(C(CC(=O)O)N2C(=O)c3ccccc3C2=O)ccc1OC.NO>>CCOc1cc(C(CC(=O)NO)N2C(=O)c3ccccc3C2=O)ccc1OC,,C1CCOC1,,Cl,,test
US20100093706A1,CC(=O)N[C@H](CC(C)C)C(=O)O.COC(=O)C1CNCCC1C>>CC(=O)N[C@H](CC(C)C)C(=O)O.COC(=O)[C@H]1CNCC[C@@H]1C,,CCO,CCOC(C)=O,,,test
US05840911,N#Cc1cccc2c1CCC2=O.S>>NC(=S)c1cccc2c1CCC2=O,,c1ccncc1,,CCN(CC)CC,,test
US20150336949A1,COc1ccc(-c2cc3c(I)cn(C(=O)OC(C)(C)C)c3nc2C2CC2)cc1N(C(=O)OC(C)(C)C)S(C)(=O)=O.Cc1nn(Cc2cccc(F)c2)c(C)c1B1OC(C)(C)C(C)(C)O1>>COc1ccc(-c2cc3c(-c4c(C)nn(Cc5cccc(F)c5)c4C)cn(C(=O)OC(C)(C)C)c3nc2C2CC2)cc1N(C(=O)OC(C)(C)C)S(C)(=O)=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20060063803A1,CCOC(=O)C=C1CCC(C(=O)O)CC1>>CCOC(=O)C[C@@H]1CC[C@@H](C(=O)O)CC1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20140154186A1,Cc1cc[nH]c1C=O.O=C1CCC(=O)N1Br>>Cc1c(Br)c[nH]c1C=O,,C1CCOC1,,,,test
US20060111360A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.C[C@H]1CN(CCCCl)[C@H](C)CN1>>C[C@H]1CN(CCCCl)[C@H](C)CN1C(=O)OC(C)(C)C,,ClCCl,,,,test
US03984421,CC(C)(N)CC(N)c1ccccc1CCN1CCCCC1.O=C(O)C(=O)O>>CC(C)(N)CC(N)c1ccccc1CCN1CCCCC1.O=C(O)C(=O)O,,CC(C)O,,,,test
US20050171109A1,COc1c(Cl)cccc1C(C)(C)CC(O)(C=O)C(F)(F)F.Cc1ccc2[nH]c(=O)ccc2c1N>>COc1c(Cl)ccc2c1C(C)(C)CC(O)(C(F)(F)F)C2Nc1c(C)ccc2[nH]c(=O)ccc12,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20100048636A1,CN(C[C@H](CC1CCC(=O)CC1)NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1>>CN(C[C@@H](N)CC1CCC(=O)CC1)C(=O)OCc1ccccc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20050070744A1,CC(C)(C)c1cccc(C(C)(C)C)c1O.OO>>CC(C)(C)C1=CC(=O)C=C(C(C)(C)C)C1=O,,CC(=O)O,,,,test
US05278316,CCOC(=O)c1cc2ccccc2n1S(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)n2c(CO)cc3ccccc32)cc1,,C1CCOC1,Cc1ccccc1,[Na+].[OH-],,test
US20150191452A1,CC(C)(C)OC(=O)N1CC(=O)C1.COc1ccc([Mg]Br)cc1>>COc1ccc(C2(O)CN(C(=O)OC(C)(C)C)C2)cc1,,C1CCOC1,,[Cl-].[NH4+],,test
US20150158879A1,CC(C)(C)OC(=O)N(CCCS(C)(=O)=O)c1ccc(Cl)cc1[N+](=O)[O-]>>CC(C)(C)OC(=O)N(CCCS(C)(=O)=O)c1ccc(Cl)cc1N,[Pd],CO,,,,test
US20100298325A1,COCCOc1cccc(N)c1.Fc1ccc(Oc2ccc(Cl)nc2)cc1>>COCCOc1cccc(Nc2ccc(Oc3ccc(F)cc3)cn2)c1,,C1COCCO1,CCOC(C)=O,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US05786523,COc1cc(NC(=O)c2ccc3cc(O)c(C(=O)Nc4cc(OC)c(NC(=O)c5ccccc5)cc4OC)cc3c2)c(OC)cc1NC(=O)c1ccccc1.ClCc1ccccc1>>COc1cc(NC(=O)c2ccc3cc(OCc4ccccc4)c(C(=O)Nc4cc(OC)c(NC(=O)c5ccccc5)cc4OC)cc3c2)c(OC)cc1NC(=O)c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140107151A1,C1CCNCC1.CC(=O)O.N#CCc1cc(-c2ncc(-c3ccc(Oc4ccccc4)cc3)c3c(N)n[nH]c23)ccn1>>N#CC(=CC1CC1)c1cc(-c2ncc(-c3ccc(Oc4ccccc4)cc3)c3c(N)n[nH]c23)ccn1,,CCO,,,,test
US20100160280A1,COc1ncccc1B1OC(C)(C)C(C)(C)O1.Nc1ccc(Oc2nccnc2Cl)cc1>>COc1ncccc1-c1nccnc1Oc1ccc(N)cc1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150152127A1,CC(=O)[C@H]1O[C@@H]2SC(N(C)C)=N[C@@H]2[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1.CC(C)(C)S(N)=O>>CC(=NS(=O)C(C)(C)C)[C@H]1O[C@@H]2SC(N(C)C)=N[C@@H]2[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1,,C1CCOC1,,,,test
US20120264748A1,CC(C)(C)OC(=O)N1CCC2(CCCNC2=O)CC1.Cl>>Cl.O=C1NCCCC12CCNCC2,,C1COCCO1,ClCCl,,,test
US08450484B2,COC(=O)c1ccc(-c2ccc(C#N)cn2)cn1>>N#Cc1ccc(-c2ccc(C(=O)O)nc2)nc1,,C1CCOC1,,O,[Li+].[OH-],test
US04778912,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.OCC(O)COCCCCCCCCCCCCC1CCCCC1>>OC(COCCCCCCCCCCCCC1CCCCC1)COC(c1ccccc1)(c1ccccc1)c1ccccc1,,CO,,CCN(CC)CC,ClCCl,test
US20080139551A1,Cc1ccc2c(c1)C(=O)C(=O)N2.Ic1ccccc1>>Cc1ccc2c(c1)C(=O)C(=O)N2c1ccccc1,,CN(C)C=O,,,,test
US20090036459A1,C1CCOC1.Fc1ccc(Br)nc1>>O=Cc1ccc(F)cn1,,CCOCC,,,,test
US20110212937A1,CNC.Fc1ccc(C2CCc3c(Cl)nc(Cl)nc32)cc1F>>CN(C)c1nc(Cl)nc2c1CCC2c1ccc(F)c(F)c1,,CO,,,,test
US05965563,O=C1NC(=O)C(c2ccc3c(c2)CCC3)(c2ncnc3ncccc23)C(=O)N1>>c1cnc2ncnc(Cc3ccc4c(c3)CCC4)c2c1,,O,,Cl,[Na+].[OH-],test
US20140024694A1,CSCC(C)n1c(C)cc2c(C(F)(F)F)c(C#N)ccc21.O=S([O-])OO>>Cc1cc2c(C(F)(F)F)c(C#N)ccc2n1C(C)CS(C)(=O)=O,,O,,CO,,test
US05866716,C=CCCCCCC.CCC(=O)O>>CCCCCCCCC(=O)O,,O,,,,test
US20140275083A1,C[C@@H](C(=O)O)N1C(=O)c2ccccc2C1=O.NCC(O)c1ccc(Cl)cc1>>C[C@@H](C(=O)NCC(O)c1ccc(Cl)cc1)N1C(=O)c2ccccc2C1=O,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20130210801A1,COc1cc2ccc(C)nc2cc1Cl>>Cc1ccc2cc(O)c(Cl)cc2n1,,ClCCl,,BrB(Br)Br,,test
US03961072,CC(=O)OC(C)=O.NC(=O)c1ccc(OCCNCC(O)COc2cccc(N)c2)cc1>>CC(=O)Nc1cccc(OCC(O)CNCCOc2ccc(C(N)=O)cc2)c1,,O,,Cl,[Na+].[OH-],test
US04371530,O=Cc1csc(Br)c1.OCCO.c1ccccc1>>c1ccc(-c2cc(C3OCCO3)cs2)cc1,Cc1ccc(S(=O)(=O)O)cc1,,,O,,test
US20120040949A1,Brc1ccc(Br)nn1.CN(C)CC(C)(C)O>>CN(C)CC(C)(C)Oc1ccc(Br)nn1,,C1CCOC1,,[H-].[Na+],,test
US20140350011A1,CC12CCC(Nc3c(Cl)cnc(N)c3[N+](=O)[O-])(CC1=O)C2(C)C>>CC12CCC(Nc3c(Cl)cnc(N)c3N)(CC1=O)C2(C)C,[Ni],CO,,,,test
US20150065464A1,CC(C)(C)[Si](C)(C)OCCBr.CCOC(=O)c1ccc(-c2cn[nH]c2)nc1>>CCOC(=O)c1ccc(-c2cnn(CCO[Si](C)(C)C(C)(C)C)c2)nc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090192156A1,COC1CCNCC1.O=C(O)c1cc(Cc2n[nH]c(=O)c3ccc(Br)cc23)ccc1F>>COC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4ccc(Br)cc34)ccc2F)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US05866564,C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(S[C@H]3C[C@@H](C(=O)N4CC(NC(=O)OCc5ccc([N+](=O)[O-])cc5)C4)N(C(=O)OCc4ccc([N+](=O)[O-])cc4)C3)[C@H](C)[C@H]12>>C[C@@H](O)[C@H]1C(=O)N2C(C(=O)O)=C(S[C@@H]3CN[C@H](C(=O)N4CC(N)C4)C3)[C@H](C)[C@H]12,[Pd],C1CCOC1,O,[H][H],,test
US04352929,O=C(O)CCSC(=S)Nc1c(F)c(F)c(F)c(F)c1F>>O=C1CCSC(=S)N1c1c(F)c(F)c(F)c(F)c1F,,CC(=O)OC(C)=O,,O=S(=O)(O)O,,test
US04870074,COc1cc(N)c(Cl)cc1C(=O)NCC1CN(Cc2ccccc2)CCO1>>COc1cc(N)c(Cl)cc1C(=O)NCC1CNCCO1,[Pd],CC(=O)O,,CCO,,test
US05234894,CC(C)(C#N)C(=O)COc1ccc(O)cc1.FC(F)(F)c1ccc2nc(Cl)cnc2c1>>CC(C)(C#N)C(=O)COc1ccc(Oc2cnc3cc(C(F)(F)F)ccc3n2)cc1,,CN(C)C=O,,O,[K],test
US20160102058A1,OC(C1CCCCC1)C1CCC2(CC1)OCCO2>>O=C1CCC(C(O)C2CCCCC2)CC1,,C1CCOC1,,Cl,,test
US20150087663A1,CC(=O)CNC(=O)c1c(N)ncnc1Cl>>Cc1cnc(-c2c(N)ncnc2Cl)o1,,Cc1ccccc1,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US20100087506A1,CC(C)[C@@H]1N(C(=O)OCc2ccccc2)CC[C@]1(O)C1CC1>>CC(C)[C@@H]1NCC[C@@]1(O)C1CC1,[Pd],O,,,,test
US20140066459A1,CC(=O)N1c2ccc(C#C[Si](C)(C)C)cc2[C@H](Nc2ccc(C#N)cn2)C[C@@H]1C>>C#Cc1ccc2c(c1)[C@H](Nc1ccc(C#N)cn1)C[C@H](C)N2C(C)=O,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US03959322,CCI.CC[C@]12CC[C@@H]3c4ccc(OC)cc4CC[C@H]3[C@@H]1CC[C@@H]2O>>CCO[C@H]1CC[C@H]2[C@@H]3CCc4cc(OC)ccc4[C@H]3CC[C@]12CC,,Cc1ccccc1C,,[H-].[Na+],,test
US20080032967A1,COC(=O)COc1ccc(NC(=O)c2cc(F)cc(N3CCC(C)CC3)c2)c2ccccc12.NN>>CC1CCN(c2cc(F)cc(C(=O)Nc3ccc(OCC(=O)NN)c4ccccc34)c2)CC1,,C1CCOC1,,,,test
US20160145247A1,CC(C)(C)S(N)=O.COC(=O)Cc1ccccc1OCc1cc(Cl)cc(C=O)c1>>COC(=O)Cc1ccccc1OCc1cc(Cl)cc(/C=N/S(=O)C(C)(C)C)c1,CC(C)O[Ti](OC(C)C)(OC(C)C)OC(C)C,Cc1ccccc1,,,,test
US20060025459A1,CC(=O)OC(C)=O.COC(=O)c1cc(N)cc(N2CCCC2=O)c1>>COC(=O)c1cc(NC(C)=O)cc(N2CCCC2=O)c1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20060003997A1,O=C(Cl)Oc1ccccc1.O=C1COc2cccnc2N1>>O=C1COc2cccnc2N1C(=O)Oc1ccccc1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US07544215B2,CCN(CCBr)c1ccc(N2C(=O)c3cccc4c([N+](=O)[O-])ccc(c34)C2=O)cc1.Cn1ccnc1>>CCN(CC[n+]1ccn(C)c1)c1ccc(N2C(=O)c3cccc4c([N+](=O)[O-])ccc(c34)C2=O)cc1.[Br-],,CC#N,,,,test
US04380465,NC(=O)c1c(Cl)nsc1-c1cccc(C(F)(F)F)c1.O=S(=O)(O)O>>O=C(O)c1c(Cl)nsc1-c1cccc(C(F)(F)F)c1,,O,O=S(=O)(O)O,O=N[O-].[Na+],,test
US20140187542A1,COCCl.COc1ccc2ncc(=O)n(CC(O)CO[Si](C)(C)C(C)(C)C)c2c1>>COCOC(CO[Si](C)(C)C(C)(C)C)Cn1c(=O)cnc2ccc(OC)cc21,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040087549A1,O=P(Cl)(Cl)Cl.Oc1ccc(Br)cc1>>O=P(Cl)(Cl)Oc1ccc(Br)cc1,,CCOCC,,CCN(CC)CC,,test
US20110070317A1,CC(C)(C)OC(=O)N[C@@H]1CCCNC1.O=C(Nc1c[nH]c2ncc(Br)c(F)c12)c1cnccn1>>CC(C)(C)OC(=O)N[C@@H]1CCCN(c2c(Br)cnc3[nH]cc(NC(=O)c4cnccn4)c23)C1,,CCCCO,,,,test
US20150038438A1,Cn1c(CO[Si](C)(C)C(C)(C)C)cc2cc3c(cc21)OCC=CC3=O>>Cn1c(CO[Si](C)(C)C(C)(C)C)cc2cc3c(cc21)OCCCC3=O,O=[Pt]=O,CCO,,,,test
US04958026,CCOC(=O)C(=O)C(=O)OCC.COc1cc(CCNC(=O)C(F)(F)F)ccc1N>>CCOC(=O)C1(O)C(=O)Nc2c(OC)cc(CCNC(=O)C(F)(F)F)cc21,,CC(=O)O,,,,test
US20100152265A1,CC(O)c1nn(C2CCCCO2)c2cc(OCc3ccccc3)ccc12.CI>>COC(C)c1nn(C2CCCCO2)c2cc(OCc3ccccc3)ccc12,,CN(C)C=O,,O,[H-].[Na+],test
US20100167927A1,CC(=O)Cl.OCCNC(=S)NC1CSc2c(F)cccc21>>CC(=O)OCCNC(=S)NC1CSc2c(F)cccc21,CN(C)c1ccncc1,C1CCOC1,CCOC(C)=O,c1ccncc1,,test
US20020099210A1,Brc1cccc(Br)n1.Fc1ccc(CBr)cc1>>Fc1ccc(Cc2cccc(Br)n2)cc1,[Zn],C1CCOC1,,O=C([O-])O.[Na+],,test
US20090076046A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN(C)Cc1c[nH]c2ncccc12>>CN(C)Cc1cn(C(=O)OC(C)(C)C)c2ncccc12,,C1CCOC1,,O,[H-].[Na+],test
US20150119379A1,C=CC(=O)Cl.CNc1cc(OC)c(Nc2ncc(C)c(-c3cn(C)c4ccccc34)n2)c(CCN(C)C)c1N>>C=CC(=O)Nc1cc(Nc2ncc(C)c(-c3cn(C)c4ccccc34)n2)c(OC)cc1N(C)CCN(C)C,,C1CCOC1,O,CCN(C(C)C)C(C)C,,test
US20100190825A1,CCCO[C@@H]1CC[C@@H](N2CCC(Nc3cc(C)c(Cl)cc3N)CC2)CC1.ClCCl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCCO[C@@H]1CC[C@@H](N2CCC(n3c(=O)[nH]c4cc(Cl)c(C)cc43)CC2)CC1.Cl,,ClCCl,O,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20130196971A1,CC(C)(C)OC(=O)N1CC[C@@H](CN)C1.COC(OC)N(C)C.NNC(=O)c1ccc(Br)cc1F>>CC(C)(C)OC(=O)N1CC[C@@H](Cn2cnnc2-c2ccc(Br)cc2F)C1,,ClCCl,,,,test
US20150005310A1,CNC(=O)[C@H]1Cc2c([nH]c3ccccc23)CN1C(=O)c1occc1C=O.Nc1ccc2nsnc2c1>>CNC(=O)[C@H]1Cc2c([nH]c3ccccc23)CN1C(=O)c1occc1CNc1ccc2nsnc2c1,,CCOC(C)=O,CO,CC[SiH](CC)CC,,test
US20060052365A1,O=C(N[C@@H](CC1CCCC1)C(=O)NC1CCCN(C(=O)OCc2ccccc2)CC1O)c1ccco1>>O=C(N[C@@H](CC1CCCC1)C(=O)NC1CCCNCC1O)c1ccco1,,ClCCl,,C[Si](C)(C)I,,test
US20100210660A1,COC(=O)c1ccc(Oc2ccc(OCc3c(-c4c(Cl)cccc4Cl)noc3C(C)C)nc2)cc1>>CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(Oc2ccc(C(=O)O)cc2)cn1,,CO,,O,[Na+].[OH-],test
US04725610,Cc1oc(-c2ccccc2)nc1C(=O)COc1ccc(C=C2SC(=O)NC2=O)cc1>>Cc1oc(-c2ccccc2)nc1C(=O)COc1ccc(CC2SC(=O)NC2=O)cc1,[Pd],C1COCCO1,,,,test
US04397847,CCOC(=O)C(F)(F)CC(=O)O>>CCOC(=O)C(F)(F)CCO,,C1CCOC1,,B,,test
US20130281433A1,CCI.CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(-c4ccc5[nH]ncc5c4)c3)sc2c1-c1ccc(Cl)cc1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(-c3ccnc(-c4ccc5c(cnn5CC)c4)c3)sc2c1-c1ccc(Cl)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120283261A1,CN1CCN(Cc2ccc(N)cc2)CC1.Cc1cnc(Cl)nc1Nc1ccc(F)c(Cl)c1>>Cc1cnc(Nc2ccc(CN3CCN(C)CC3)cc2)nc1Nc1ccc(F)c(Cl)c1,,CO,ClCCl,,,test
US20050261291A1,CCC=O.COc1cc(N2CCNCC2)c(C2CC(C)(C)CC(C)(C)C2)cc1N1CCCCC1>>CCCN1CCN(c2cc(OC)c(N3CCCCC3)cc2C2CC(C)(C)CC(C)(C)C2)CC1,,C1CCOC1,CCOC(C)=O,O=C([O-])O.[Na+],,test
US20080114023A1,O=C([O-])NCCc1cn(S(=O)(=O)c2ccc(F)cc2F)c2ccncc12>>NCCc1cn(S(=O)(=O)c2ccc(F)cc2F)c2ccncc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US04609758,CC(C)NC(C)C.CN(C)C(=O)COc1ccc(Cl)cc1.O=C1CCCCC1.[Li]CCCC>>CC(C)[N-]C(C)C.CN(C)C(=O)C(Oc1ccc(Cl)cc1)C1(O)CCCCC1.[Li+],,C1CCOC1,,[Cl-].[NH4+],,test
US04175130,CCBr.O=C(O)Cc1nc(-c2ccc(Cl)cc2)oc1Sc1ccccc1>>CCOC(=O)Cc1nc(-c2ccc(Cl)cc2)oc1Sc1ccccc1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,O,test
US20060069132A1,CCOC(=O)c1ccn(C(C)(C)C)n1.O=C1CCC(=O)N1Br>>CCOC(=O)c1nn(C(C)(C)C)cc1Br,,CN(C)C=O,,,,test
US20090291945A1,CC(C)C[C@H](N[C@@H](c1ccccc1)C(F)(F)F)C(=O)N[C@@H](CCCC(=O)OC(C)(C)C)CNc1ccc(N2CCOCC2)cc1>>CC(C)C[C@H](N[C@@H](c1ccccc1)C(F)(F)F)C(=O)N[C@@H](CCCC(=O)O)CNc1ccc(N2CCOCC2)cc1,,ClCCl,,Cl,,test
US20110009391A1,NC1C2CC3CC(C2)CC1C3.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.c1cnc(COc2ccc(N3CCNc4ccccc43)cc2)nc1>>O=C(NC1C2CC3CC(C2)CC1C3)N1CCN(c2ccc(OCc3ncccn3)cc2)c2ccccc21,,ClCCl,,CCN(CC)CC,Cl,test
US20070270587A1,COC[C@@H]1Cc2ccccc2N1C(=O)OC(C)(C)C>>COC[C@@H]1Cc2ccccc2N1,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US06187393B1,CCC/C=C/C(=O)O.CCCCCC12CCC(c3ccc(-c4ncc(O)cn4)cc3)(CC1)CC2>>CCC/C=C/C(=O)Oc1cnc(-c2ccc(C34CCC(CCCCC)(CC3)CC4)cc2)nc1,CN(C)c1ccncc1,ClCCl,,,,test
US05464788,CC(=O)Cl.COc1cc(OC2CCNCC2)ccc1C(=O)O>>COc1cc(OC2CCN(C(C)=O)CC2)ccc1C(=O)O,,C1CCOC1,,CCN(CC)CC,,test
US20070078136A1,N[C@H]1CC[C@H](N)CC1.O=C(Nc1cccn(-c2ccc(F)cc2)c1=O)c1ccc(Nc2cc(Cl)nn3ccnc23)cc1>>N[C@@H]1CC[C@@H](Nc2cc(Nc3ccc(C(=O)Nc4cccn(-c5ccc(F)cc5)c4=O)cc3)c3nccn3n2)CC1,,O,,,,test
US20080058342A1,CC(=O)CCl.COc1cc2c(Oc3ccc4[nH]c(C)cc4c3)ncnc2cc1OCCN1CCNCC1>>COc1cc2c(Oc3ccc4[nH]c(C)cc4c3)ncnc2cc1OCCN1CCN(CC(C)=O)CC1,,CC(=O)N(C)C,,O=C([O-])[O-].[K+].[K+],,test
US20120108582A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(C)(C)OC(=O)[C@@]12CC[C@@H](F)[C@@H]1CN(C(=O)OCc1ccccc1)C2.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N[C@@]12CC[C@@H](F)[C@@H]1CN(C(=O)OCc1ccccc1)C2,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20110150834A1,CC#N.Cc1cc(C)c(Cc2ccccc2S(=O)(=O)N2CCCC2)[nH]1>>Cc1[nH]c(Cc2ccccc2S(=O)(=O)N2CCCC2)c(C)c1C#N,,CC#N,,CN(C)C=O,,test
US20160272596A1,CC(=O)CCCC(=O)O.C[C@@H](C(=O)N[C@H]1CNc2ccccc2NC1=O)N(C)C(=O)OC(C)(C)C>>CC(=O)CCCC(=O)N1C[C@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C(=O)Nc2ccccc21,,c1ccncc1,,O=P(Cl)(Cl)Cl,,test
US20090156642A1,CN(Cc1cc(-c2cccnc2F)c(S(=O)(=O)c2nccs2)s1)C(=O)OC(C)(C)C.Cl>>CNCc1cc(-c2cccnc2F)c(S(=O)(=O)c2nccs2)s1.Cl,,CCOC(C)=O,,,,test
US20060025350A1,COC1C[C@@H](OCc2ccccc2)[C@H](O)[C@@H](COS(=O)(=O)c2ccc(C)cc2)O1.O=C(Cl)c1ccccc1>>COC1C[C@@H](OCc2ccccc2)[C@H](OC(=O)c2ccccc2)[C@@H](COS(=O)(=O)c2ccc(C)cc2)O1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US20120202776A1,CP(C)(=O)c1ccc(Nc2ncnc(Cl)n2)cc1.NCCN1CCOCC1>>CP(C)(=O)c1ccc(Nc2ncnc(NCN3CCOCC3)n2)cc1,,CCO,,CCN(CC)CC,,test
US20070259898A1,O=C(OCc1ccccc1)[C@H]1CC[C@@H](N(CCOCc2ccccc2)C(=O)CC[C@H](NCc2cc(Oc3ccccc3)ncc2[N+](=O)[O-])C2CCOCC2)CC1>>Nc1cnc(Oc2ccccc2)cc1CN[C@@H](CCC(=O)N(CCOCc1ccccc1)[C@@H]1CC[C@H](C(=O)OCc2ccccc2)CC1)C1CCOCC1,[Zn],CO,,[Cl-].[NH4+],,test
US20090318501A1,CN(C[C@@H](N)C[C@H]1CCCOC1)C(=O)OCC[Si](C)(C)C.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CN(C[C@H](C[C@H]1CCCOC1)NC(=O)Oc1ccc([N+](=O)[O-])cc1)C(=O)OCC[Si](C)(C)C,,CC#N,,O=C([O-])O.[Na+],,test
US20140323468A1,CC(=O)N1CC=C(c2cncc(-c3cnc4c(c3)CCCN4C(N)=O)c2)CC1>>CC(=O)N1CCC(c2cncc(-c3cnc4c(c3)CCCN4C(N)=O)c2)CC1,[Pd],CO,,O=C[O-].[NH4+],,test
US20070112005A1,C=C1CC(C(=O)O)C1.CCI>>C=C1CC(C(=O)OCC)C1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04045209,CNC(=O)Nc1ccc(Cl)c(Cl)c1.CSCl>>CSN(C)C(=O)Nc1ccc(Cl)c(Cl)c1,,c1ccncc1,,CCOCC,O,test
US20140194418A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1c(Br)ccc(N)c1Cl.CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1>>CC(C)(C)OC(=O)N1CC=C(c2ccc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(Cl)c2)CC1,,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20090247526A1,CCOC(=O)c1ccc(Cl)c(Oc2cc(NC(N)=S)ncc2Br)c1.O=C(CBr)CCc1ccccc1>>CCOC(=O)c1ccc(Cl)c(Oc2cc(Nc3nc(CCc4ccccc4)cs3)ncc2Br)c1,,CCO,,CCN(CC)CC,,test
US20100121091A1,CS(=O)(=O)Cl.O=C(NCCOC1CCCCO1)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1N(CCO)CCI>>CS(=O)(=O)OCCN(CCI)c1c(C(=O)NCCOC2CCCCO2)cc([N+](=O)[O-])cc1[N+](=O)[O-],,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US04530922,C[Si](C)(C)Cl.O[Si](Cn1ccnc1)(c1ccc(F)cc1)c1ccc(F)cc1>>C[Si](C)(C)O[Si](Cn1ccnc1)(c1ccc(F)cc1)c1ccc(F)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20060264474A1,COC(OC)c1cc(-c2cccc(C(C)(C)N)c2)n(C)n1.O=S(=O)(Cl)CC(F)(F)F>>COC(OC)c1cc(-c2cccc(C(C)(C)NS(=O)(=O)CC(F)(F)F)c2)n(C)n1,,ClCCl,,CCN(CC)CC,,test
US20060079687A1,CN(C(=O)CCN)C1CCCCC1.O=Cc1cc(C(=O)c2ccccc2)ccc1[N+](=O)[O-]>>CN(C(=O)CCNCc1cc(C(=O)c2ccccc2)ccc1[N+](=O)[O-])C1CCCCC1,,ClCCCl,,O=C([O-])O.[Na+],,test
US20160106754A1,CC(=O)NN1C(=O)C2=C(CC1(C)C)Nc1ccc(OC(F)(F)F)cc1S2>>CC1(C)CC2=C(Sc3cc(OC(F)(F)F)ccc3N2)C(=O)N1N,,CO,,Cl,,test
US20160257662A1,CS(=O)(=O)N1CCN(C(=O)[C@H](CCC(=O)O)NC(=O)c2ccc(F)cc2)CC1>>CS(=O)(=O)N1CCN(C(=O)[C@H](CCCO)NC(=O)c2ccc(F)cc2)CC1,,C1CCOC1,O,,,test
US20160272631A1,O=C(Cl)c1ccccc1C(F)(F)F.c1ccn2cncc2c1>>O=C(c1ccccc1C(F)(F)F)c1ncc2ccccn12,,C1CCOC1,,[Li]CCCC,,test
US04987235,CC(=O)OC(C)=O.Oc1cc2c(cc1O)CNC2.c1ccncc1>>CC(=O)Oc1cc2c(cc1OC(C)=O)NC(C(C)=O)C2,,c1ccncc1,,Br,,test
US20040254226A1,CC(C)(C)OC(=O)N(CCS(=O)(=O)c1ccccc1)CC(=O)O.N#C[C@@H]1CCCN1>>CC(C)(C)OC(=O)N(CCS(=O)(=O)c1ccccc1)CC(=O)N1CCC[C@H]1C#N,,ClCCl,,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US20150225400A1,CC(C)[Mg]Cl.CCOc1ccc(F)c(-c2cc(Cl)nc(C#N)c2)c1>>CCOc1ccc(F)c(-c2cc(C#N)nc(C(C)C)c2)c1,,C1CCOC1,CCOCC,CN1CCCC1=O,,test
US20160193218A1,BrP(Br)Br.COc1cc(OC)c2c(=O)[nH]c(-c3ncc(OCCO)cc3F)nc2c1>>COc1cc(OC)c2c(=O)[nH]c(-c3ncc(OCCBr)cc3F)nc2c1,,CN(C)C=O,,,,test
US06432880B1,CC(=O)Oc1cnc(Cl)c(Cl)c1>>Oc1cnc(Cl)c(Cl)c1,,O,,[Na+].[OH-],,test
US04593039,COc1cc(NC(=S)NCCN)cc(OC)c1.N#Cc1ccccc1OCC1CO1>>COc1cc(NC(=S)NCCNCC(O)COc2ccccc2C#N)cc(OC)c1,,CC(C)O,,,,test
US08114866B2,CCOC(=O)COC(=O)N1CCN(c2ccc(-c3ccc(C(F)(F)F)cc3)cn2)CC1.CN>>CNC(=O)COC(=O)N1CCN(c2ccc(-c3ccc(C(F)(F)F)cc3)cn2)CC1,,C1CCOC1,,,,test
US05556864,COc1cccc(CCc2ccccc2OC[C@@H]2CN(C(=O)OC(C)(C)C)CCO2)c1>>COc1cccc(CCc2ccccc2OC[C@@H]2CN(C)CCO2)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20150166480A1,CS(=O)(=O)c1ccc(-c2ccc(OCC3CCN(C(=O)C4(C(F)(F)F)CC4)CC3)cc2)cc1>>CS(=O)(=O)c1ccc(-c2ccc(OCC3CCN(CC4(C(F)(F)F)CC4)CC3)cc2)cc1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20150259323A1,CCOc1ccccc1O[C@@H]1CCCN(c2ncc(C(=O)NCc3cc(OC)cc(C(=O)OC)c3)cn2)C1>>CCOc1ccccc1O[C@@H]1CCCN(c2ncc(C(=O)NCc3cc(OC)cc(C(=O)O)c3)cn2)C1,,C1CCOC1,O,[Li]O,,test
US20150031689A1,CC(C)(C)OC(=O)N1CCC[C@@H](N)C1.Clc1ccc(-n2c(-c3ccccc3Cl)nc3c(Cl)ncnc32)cc1>>CC(C)(C)OC(=O)N1CCC[C@@H](Nc2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)C1,,CCO,,CCN(CC)CC,,test
US20090176778A1,CCOC(=O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1[N+](=O)[O-].NCc1cccs1>>CCOC(=O)c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1NCc1cccs1,,CN1CCCC1=O,,,,test
US20100076026A1,CCCCN(C(=O)NC1CCCCC1)c1c2ccccc2nn1-c1ccc(Cl)cc1.NCc1ccccc1>>Clc1ccc(-n2nc3ccccc3c2NCc2ccccc2)cc1,,CN1CCCC1=O,,,,test
US20050107377A1,C1COCCN1.Fc1ccc2c(-c3ccc(OC[C@@H]4CO4)cc3)noc2c1>>O[C@H](COc1ccc(-c2noc3cc(F)ccc23)cc1)CN1CCOCC1,,CCO,CN(C)C=O,,,test
US20080188528A1,BrCc1ccccc1Br.COC(=O)c1ccc[nH]c1=O>>COC(=O)c1cccn(Cc2ccccc2Br)c1=O,,CN(C)C=O,,Cl,[H-].[Na+],test
US20130165492A1,CCOC(=O)C(CC)CC.CI>>CCOC(=O)C(C)(CC)CC,,C1CCOC1,,,,test
US04920129,C#CCc1c(C)nc2c(NCc3c(C)cccc3NC(=O)OC)cccn12.Cl>>C#CCc1c(C)nc2c(NCc3c(C)cccc3NC(=O)OC)cccn12.Cl,,CO,,,,test
US20150224113A1,COCCCNC(=O)c1ccc(Cl)nc1.NN>>COCCCNC(=O)c1ccc(NN)nc1,,CC(C)O,,Cc1ccccc1,,test
US20090036493A1,CCCC[Sn](CCCC)(CCCC)c1ccccn1.O=C1c2ccccc2C(=O)N1Cc1ccc2c(c1)ncn2-c1cccc(Br)c1>>O=C1c2ccccc2C(=O)N1Cc1ccc2c(c1)ncn2-c1cccc(-c2ccccn2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,,,test
US05905071,CCCCCCCC/C=C\CCCCCCCC(=O)N(CCCCCCCCCCCCCC)[C@]1(N)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1C(=O)CN.C[C@H](NC(=O)OC(C)(C)C)C(=O)O>>CCCCCCCC/C=C\CCCCCCCC(=O)N(CCCCCCCCCCCCCC)[C@]1(N)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1C(=O)CNC(=O)[C@H](C)NC(=O)OC(C)(C)C,,C1CCOC1,,,,test
US08129361B2,O=C1CCC(=O)N1Br.OCCCc1cccs1>>BrCCCc1cccs1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20160009744A1,OC(c1cc(C2OCCO2)sc1Cl)c1ncccc1CCI>>Clc1sc(C2OCCO2)cc1C1OCCc2cccnc21,O=[Ag-],,,CCOCC,,test
US20070244173A1,Cc1nc2c3c(ccc2n1C)[C@@H](OCCF)[C@H](O)[C@@H](c1ccccc1)O3>>Cc1nc2c3c(ccc2n1C)[C@H]1OCCO[C@@H]1[C@@H](c1ccccc1)O3,,CN(C)C=O,,[H-].[Na+],,test
US20060235033A1,CC[C@@H](N)c1ccccc1.COc1cc2nccc(Oc3ccc(N)cc3)c2cc1OC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC[C@@H](NC(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1)c1ccccc1,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20150094330A1,COC(=O)c1ccc(CCc2cccc3c2C(=O)CC3)cc1.COc1ccc(OC)c(C[Mg]Cl)c1>>COC(=O)c1ccc(CCc2cccc3c2C(O)(Cc2cc(OC)ccc2OC)CC3)cc1,,C1CCOC1,,,,test
US20100292253A1,CN.COC(=O)CNC(=O)c1cncc(F)c1>>CNC(=O)CNC(=O)c1cncc(F)c1,,CCO,,,,test
US20090062274A1,CCN.CCOC(=O)c1c(C)nc(SC)nc1Cl>>CCNc1nc(SC)nc(C)c1C(=O)OCC,,C1CCOC1,,CCN(CC)CC,,test
US20100273806A1,C#Cc1cc(OC(F)(F)F)cc(-c2nc(-c3ccc4[nH]c5c(c4c3)CCC5CC(=O)O)no2)c1>>CCc1cc(OC(F)(F)F)cc(-c2nc(-c3ccc4[nH]c5c(c4c3)CCC5CC(=O)O)no2)c1,[Pd],CCOC(C)=O,,[H][H],,test
US05449674,Clc1ccc2c(c1)NCc1ccccc1O2.O=C(Cl)Cl>>O=C(Cl)N1Cc2ccccc2Oc2ccc(Cl)cc21,,CCOCC,Cc1ccccc1,CCN(CC)CC,,test
US20120190635A1,CC(=O)OC1C(F)OC(C)CC1N(C)C.OC1CCCC2CCCCC12>>CC(=O)OC1C(OC2CCCC3CCCCC32)OC(C)CC1N(C)C,,CCOC(C)=O,,CCOCC,FB(F)F,test
US20120022043A1,O=C(CBr)c1cc(Cl)ccc1Cl.O=C1NC(=O)c2ccccc21>>O=C(CN1C(=O)c2ccccc2C1=O)c1cc(Cl)ccc1Cl,,CN(C)C=O,,O,[K],test
US20150018363A1,Cc1c(C2CC2)nc2ccc(-n3ccc(O)cc3=O)cn12.OCc1ccc(C(F)F)s1>>Cc1c(C2CC2)nc2ccc(-n3ccc(OCc4ccc(C(F)F)s4)cc3=O)cn12,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US04960884,BrP(Br)Br.OCc1cccc(OCCF)c1OCCF>>FCCOc1cccc(CBr)c1OCCF,,CCOCC,,,,test
US20090163488A1,Cc1ccc(S(=O)(=O)N=c2ccc(Oc3cccc(NC(=O)c4cccc(C)n4)c3)cn2CC(N)=O)cc1>>Cc1cccc(C(=O)Nc2cccc(Oc3ccc4nc(N)cn4c3)c2)n1,,C1CCOC1,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US20150111914A1,C=C(C(=O)O)C(C)c1ccc(C(=O)OC)cc1.Nc1c(Br)ccc[n+]1[O-]>>C=C(C(=O)Nc1c(Br)ccc[n+]1[O-])C(C)c1ccc(C(=O)OC)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050208582A1,COC(C)=N.COc1c(C(=O)NN)ccc2[nH]nc(/C=C/c3cccc(F)c3)c12>>COc1c(-c2nc(C)n[nH]2)ccc2[nH]nc(/C=C/c3cccc(F)c3)c12,,CCO,,CCN(CC)CC,Cl,test
US05416236,CCOC(=O)Nc1cc(NS(=O)(=O)CC)ccc1F.ClCl>>CCOC(=O)Nc1cc(NS(=O)(=O)CC)c(Cl)cc1F,,C1COCCO1,O,,,test
US06559100B1,COC(=O)c1ccc(C=S(=O)=O)c(CC2=NOCC2)c1Cl>>O=C(O)c1ccc(C=S(=O)=O)c(CC2=NOCC2)c1Cl,,C1CCOC1,CCOCC,Cl,[Li+].[OH-],test
US20100113502A1,CC1CCN(C(=O)c2ccc3[nH]c4c(c3c2)CN(C(=O)OC(C)(C)C)CC4)CC1.CS(=O)(=O)c1ccc(CCl)cc1>>CC1CCN(C(=O)c2ccc3c(c2)c2c(n3Cc3ccc(S(C)(=O)=O)cc3)CCN(C(=O)OC(C)(C)C)C2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20090124695A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.CCCCCC(C)(O)/C=C/[C@H]1[C@H](OC(=O)c2ccccc2)C[C@@H]2OC(=O)C[C@@H]21>>CCCCCC(C)(/C=C/[C@H]1[C@H](OC(=O)c2ccccc2)C[C@@H]2OC(=O)C[C@@H]21)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C,,CCOC(C)=O,CN(C)C=O,c1c[nH]cn1,,test
US20040204386A1,ClCc1ccc(Cl)cc1.Nc1nc(Nc2ccc(Cl)cc2)cc(-c2cc(Br)ccc2O)n1>>Nc1nc(Nc2ccc(Cl)cc2)cc(-c2cc(Br)ccc2OCc2ccc(Cl)cc2)n1,,CC#N,,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US20100137313A1,CCOC(=O)c1cncc(-c2cnc(Nc3ccc(F)c(Cl)c3)nc2S(C)(=O)=O)c1.NCCc1c[nH]cn1>>CCOC(=O)c1cncc(-c2cnc(Nc3ccc(F)c(Cl)c3)nc2NCCc2c[nH]cn2)c1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,O,test
US20140336377A1,Cc1nc(Br)ccc1Br.OCC(F)F>>Cc1nc(OCC(F)F)ccc1Br,,C1CCOC1,,O,CC(C)(C)[O-].[K+],test
US04282212,N#CC1NC1c1ccccc1.O=C=NC(=O)CCl>>N#CC1C(c2ccccc2)N1C(=O)NC(=O)CCl,,CCOCC,,,,test
US05034393,CC(C)(C)c1ccc(CCO)cc1.Clc1ncnc2ncccc12>>CC(C)(C)c1ccc(CCOc2ncnc3ncccc23)cc1,,Cc1ccccc1,,Cl,,test
US04289766,CCC1NCCCS1.S=C=Nc1cccc(Cl)c1>>CCC1SCCCN1C(=S)Nc1cccc(Cl)c1,,CCCCCC,,c1ccccc1,,test
US06046220,CC1(C)CCC(C)(C)c2cc(CC#Cc3ccc(C(=O)O)c(O)c3)ccc21.OCCNCCO>>CC1(C)CCC(C)(C)c2cc(CC#Cc3ccc(C(=O)O)c(O)c3)ccc21.OCCNCCO,,CO,,,,test
US05977125,CC1(C)CCC(C)(C)c2nc3c(nc21)CCCC3.O>>CC1(C)CCC(C)(C)c2nc3c(nc21)CCCC3=O,,CC(=O)O,,,,test
US20150218160A1,CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3c(c2)CN[C@H]3C(C)C)cc1.N#Cc1ccc(S(=O)(=O)Cl)cc1>>CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3c(c2)CN(S(=O)(=O)c2ccc(C#N)cc2)[C@H]3C(C)C)cc1,,ClCCl,,CCN(CC)CC,,test
US20140070204A1,O=[N+]([O-])c1ccccc1-c1ccc(Cl)cc1>>Clc1ccc2c(c1)[nH]c1ccccc12,,Clc1ccccc1Cl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20050197325A1,CC(C)(C)OC(=O)N[C@@H]1CCCC[C@@]12CCCN(Cc1ccc(F)cc1)C2>>N[C@@H]1CCCC[C@@]12CCCN(Cc1ccc(F)cc1)C2,,ClCCl,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20090012074A1,CCC(=O)NC1COc2cc(NS(=O)(=O)c3ccc(OC(F)(F)F)cc3)cnc2C1>>CCCNC1COc2cc(NS(=O)(=O)c3ccc(OC(F)(F)F)cc3)cnc2C1,,C1CCOC1,,B,,test
US20100291151A1,Cn1cccn1.O=Cc1ccccc1>>Cn1nccc1C(O)c1ccccc1,,C1CCOC1,CCOC(C)=O,[Li]CCCC,[Cl-].[NH4+],test
US20040192735A1,C#CCN.O=C(O)c1ccccc1Nc1ccc2c(C#Cc3ccccn3)n[nH]c2c1>>C#CCNC(=O)c1ccccc1Nc1ccc2c(/C=C/c3ccccn3)n[nH]c2c1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090270369A1,COC(CCBr)OC.Cn1c(=O)[nH]c2c(c1=O)CCCC2>>COC(CCn1c2c(c(=O)n(C)c1=O)CCCC2)OC,,CO,,CC(C)(C)[O-].[K+],,test
US20120010183A1,C1CCOC1.CC(C)(C)[Si](C)(C)Oc1ccc2[nH]ncc2c1.CCOC(C)=O>>CC(C)n1ncc2cc(O[Si](C)(C)C(C)(C)C)ccc21,,CCOC(C)=O,,[H-].[Na+],,test
US05266319,O=C1O[C@H]2[C@@H]3OC(=O)c4cc(O)c(O)c(O)c4-c4c(cc(O)c(O)c4O)C(=O)OC[C@H]2O[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H]3OC(=O)c2cc(O)c(O)c3c2[C@@H]2C1=CC(=O)[C@](O)(O3)C2(O)O>>O=C(O[C@@H]1O[C@@H]2COC(=O)c3cc(O)c(O)c(O)c3-c3c(cc(O)c(O)c3O)C(=O)O[C@H]([C@H]1O)[C@@H]2O)c1cc(O)c(O)c(O)c1,,O,,,,test
US20090143357A1,C=O.Cc1ccc(OCC2CNCCO2)c(NC(=O)Nc2cnc(C#N)cn2)c1>>Cc1ccc(OCC2CN(C)CCO2)c(NC(=O)Nc2cnc(C#N)cn2)c1,,CO,,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20140005132A1,CC(C)(C)[Si](O[C@H]1CC[C@@]2(C)C(=CCC3C2CC[C@@]2(C)C3CC[C@@H]2C2=CC(=O)OC2)C1)(c1ccccc1)c1ccccc1>>C[C@]12CC[C@H](O)CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2C1=CC(=O)OC1,,CO,,,,test
US20050075334A1,CS(=O)(=O)c1nc2cc(Cl)ccc2[nH]1.O=c1[nH]c2cccc(S)c2[nH]1>>O=c1[nH]c2cccc(Sc3nc4cc(Cl)ccc4[nH]3)c2[nH]1,,CC(C)O,,,,test
US20150239847A1,CC(=O)/C=N/O.NNc1c(F)cccc1F>>CC(C=NO)=NNc1c(F)cccc1F,,CCO,,,,test
US20080009462A1,C=CCCCCCCCCCCCCCCO[Si](C)(C)C(C)(C)C>>C=CCCCCCCCCCCCCCCO,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05451686,CC1OC(=O)C(c2ccccc2)=C1CO.CCCCCCCCCCCC(=O)Cl>>CCCCCCCCCCCC(=O)OCC1=C(c2ccccc2)C(=O)OC1C,,C1CCOC1,,CCN(CC)CC,CN(C)c1ccccn1,test
US20100210577A1,NNc1ccccc1C(=O)O.O=C(O)CSC(=S)SCC(=O)O>>O=C(O)c1ccccc1NN1C(=O)CSC1=S,,O,,Cl,[Na+].[OH-],test
US20090054508A1,CN1CCN(c2ccc(N)c(C=Cc3n[nH]c4ccccc34)c2)CC1.Cc1ccsc1C(=O)Cl>>Cc1ccsc1C(=O)Nc1ccc(N2CCN(C)CC2)cc1/C=C/c1n[nH]c2ccccc12,,C1CCOC1,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20100273764A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(Cl)cnc3Nc3ccc(NC(=O)OC(C)(C)C)nc3)n2)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(Cl)cnc3Nc3ccc(N)nc3)n2)cc1,,ClCCl,,Cc1ccccc1,O=C(O)C(F)(F)F,test
US20160264548A1,CC(C)(C)OC(=O)N1CCCC(N)C1.COC(=O)c1cc(I)cnc1Cl.N.N#CBr.Oc1ccc(Oc2ccc(F)cc2F)cc1>>N#CN1CCC(Nc2cnc(Oc3ccc(Oc4ccc(F)cc4F)cc3)c(C(N)=O)c2)C1,,CO,Cl,,,test
US05650428,CCC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C(O)=S.CCOC(=O)c1cccc(N)c1>>CCC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C(=S)Nc1cccc(C(=O)OCC)c1,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20120283264A1,CC(C)(C)OC(=O)N[C@H](c1ccnc(Br)c1)[C@H](O)c1ccccc1>>O=C1N[C@H](c2ccnc(Br)c2)[C@@H](c2ccccc2)O1,,O=C(O)C(F)(F)F,,O=C(n1ccnc1)n1ccnc1,,test
US20100280005A1,COCCCC[C@@](O)(c1ccccc1Oc1ccccc1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1>>COCCCCC(O)(c1ccccc1Oc1ccccc1)[C@@H]1CCCNC1,,CC#N,,Cl,[Na+].[OH-],test
US06930152B2,CCC1Cc2c(-c3ccccc3)cccc2C1O>>CCc1cccc2c1CC(c1ccccc1)C2=O,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20150126449A1,N#Cc1c(F)cccc1F.c1nc[nH]n1>>N#Cc1c(F)cccc1-n1cncn1,,CS(C)=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20120071480A1,C1COCCN1.COc1cc(Nc2cc(Cl)nc(N[C@@H](C)c3ncc(F)cn3)n2)n[nH]1>>COc1cc(Nc2cc(N3CCOCC3)nc(N[C@@H](C)c3ncc(F)cn3)n2)n[nH]1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20110183960A1,NC(=O)C1(c2ccccc2)CCN(C(=O)c2cc(-c3ccc(O)cc3)c(-c3ccc(Cl)cc3Cl)s2)CC1.OCCCCl>>NC(=O)C1(c2ccccc2)CCN(C(=O)c2cc(-c3ccc(OCCCO)cc3)c(-c3ccc(Cl)cc3Cl)s2)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130274244A1,Cc1nn(Cc2cccc(C3CC3)n2)c2ccc(F)c(C(=O)O)c12.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>Cc1nn(Cc2cccc(C3CC3)n2)c2ccc(F)c(N)c12,,CN(C)C=O,O,,,test
US20070066618A1,CS(=O)c1cc([N+](=O)[O-])c(Cl)cc1Cl.O=C(OO)c1cccc(Cl)c1>>CS(=O)(=O)c1cc([N+](=O)[O-])c(Cl)cc1Cl,,ClCCl,,O=C([O-])O.[Na+],,test
US20090018163A1,Cc1ccc2nccc(C(F)(F)F)c2c1.O=C1CCC(=O)N1Br>>FC(F)(F)c1ccnc2ccc(CBr)cc12,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20120196813A1,CCOc1ccc(Cc2cc([C@@H]3OC(CI)(CI)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)ccc2Cl)cc1>>CCOc1ccc(Cc2cc([C@@H]3OC(C)(C)[C@@H](OCc4ccccc4)[C@H](OCc4ccccc4)[C@H]3OCc3ccccc3)ccc2Cl)cc1,,CO,Cc1ccccc1,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20100331326A1,Cc1ccc(Br)cn1.O=C1NCCN1c1ccc2ncsc2c1>>Cc1ccc(N2CCN(c3ccc4ncsc4c3)C2=O)cn1,I[Cu]I,C1COCCO1,,N[C@@H]1CCCC[C@H]1N,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20110112063A1,Cc1cc(Nc2nc(Cl)ncc2Cl)n[nH]1.Cc1cc([C@H]2COC(=O)N2)c(C)cc1N>>Cc1cc(Nc2nc(Nc3cc(C)c([C@H]4COC(=O)N4)cc3C)ncc2Cl)n[nH]1,,CC(C)O,,Cl,,test
US20120115845A1,CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc3nc(N)sc3c2)CC1.NC(=O)c1cc(-n2cccn2)ccc1Cl.O=C(Cl)C(=O)Cl>>CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc3nc(NC(=O)NC(=O)c4cc(-n5cccn5)ccc4Cl)sc3c2)CC1,,CN(C)C=O,ClCCCl,C1COCCO1,,test
US20040224974A1,COCC#Cc1ccccn1.Cc1cc(C)c(S(=O)(=O)ON)c(C)c1>>COCC#Cc1cccc[n+]1N.Cc1cc(C)c(S(=O)(=O)[O-])c(C)c1,,ClCCl,,CCOCC,,test
US20130046004A1,CC(C)(C)C(=O)CBr.COC(=O)c1cc(O)n(-c2ccccc2F)n1>>COC(=O)c1cc(OCC(=O)C(C)(C)C)n(-c2ccccc2F)n1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05539112,CCOC(=O)Nc1c(F)ccc(O)c1C(=O)OCC.COCCl>>CCOC(=O)Nc1c(F)ccc(OCOC)c1C(=O)OCC,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20020183327A1,COc1ccc(C=O)cc1OC.Cc1ccc(N)nc1.[C-]#[N+]CCCCCC[N+]#[C-]>>[C-]#[N+]CCCCCCNc1c(-c2ccc(OC)c(OC)c2)nc2ccc(C)cn12,,[O-][Cl+3]([O-])([O-])O,,,,test
US20160257658A1,NC(N)=S.O=C(CBr)c1cccc(Br)c1>>Nc1nc(-c2cccc(Br)c2)cs1,,CCO,,,,test
US20150051395A1,COC(=O)c1cc(F)c(NS(=O)(=O)c2ccc(-c3cnc(C4CCOCC4)nc3)cc2)cc1F>>O=C(O)c1cc(F)c(NS(=O)(=O)c2ccc(-c3cnc(C4CCOCC4)nc3)cc2)cc1F,,CO,,Cl,[Li+].[OH-],test
US20090023789A1,CCCCc1cn(C(C)(C)C)s/c1=N\C(=O)c1cc(Cl)ccc1O.N#CCBr>>CCCCc1cn(C(C)(C)C)s/c1=N\C(=O)c1cc(Cl)ccc1OCC#N,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20100137281A1,COC(=O)c1cc(C)sc1N.COc1ccc(C(=O)CN)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc(C(=O)Cn2c(=O)[nH]c3sc(C)cc3c2=O)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20080280925A1,COc1ccc(N)c(NC(=O)c2cc(C(F)(F)F)nn2C2CCN(CCN(C)C(=O)OC(C)(C)C)CC2)c1>>COc1ccc2[nH]c(-c3cc(C(F)(F)F)nn3C3CCN(CCN(C)C(=O)OC(C)(C)C)CC3)nc2c1,,CC(=O)O,,O=C([O-])[O-].[Na+].[Na+],,test
US20150299224A1,Cc1csc(Br)n1.Nc1cc(Cl)c(B(O)O)cn1>>Cc1csc(-c2cnc(N)cc2Cl)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US05998412,CN(OCc1ccccc1)C(=O)[C@H]1CCCCN1S(=O)(=O)N1CCC(c2c[nH]c3ccc(F)cc23)CC1>>CN(O)C(=O)[C@H]1CCCCN1S(=O)(=O)N1CCC(c2c[nH]c3ccc(F)cc23)CC1,[Pd],C1CCOC1,CCO,,,test
US20080070920A1,CC(C)=O.COc1nc(Cl)c(Br)c(OC)n1>>COc1nc(Cl)c(C(C)(C)O)c(OC)n1,,C1CCOC1,,[Li]CCCC,,test
US20040082571A1,CCc1cc(C(F)(F)F)n[nH]1.O=C1CCC(=O)N1Cl>>CCc1[nH]nc(C(F)(F)F)c1Cl,,CC#N,,,,test
US20140018393A1,CC(=O)C1CCN(C(=O)OC(C)(C)C)CC1.N[C@@H]1C[C@H]1c1ccccc1>>CC(N[C@@H]1C[C@H]1c1ccccc1)C1CCN(C(=O)OC(C)(C)C)CC1,,ClC(Cl)Cl,,CC(=O)O,O=C([O-])O.[Na+],test
US05252741,N#Cc1cccnc1.Nc1ccccc1>>c1ccc(NCc2cccnc2)cc1,[Rh],,,[H][H],,test
US05262390,COC(=O)C(C)Oc1cc(C)ccc1CCl.O=c1n(CCCF)nnn1-c1ccc(O)cc1F>>COC(=O)C(C)Oc1cc(C)ccc1COc1ccc(-n2nnn(CCCF)c2=O)c(F)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06417192B1,O=C(CCCCCCCBr)c1ccc(F)cc1>>Fc1ccc(CCCCCCCCBr)cc1,,CCOCC,,CC[SiH](CC)CC,,test
US20090208485A1,COC1COCCC1=O.Cc1cc(C(F)(F)F)cc(N2CCN(C(=O)[C@@]3(C(C)C)CC[C@@H](N)C3)CC2)n1>>COC1COCCC1N[C@@H]1CC[C@@](C(=O)N2CCN(c3cc(C(F)(F)F)cc(C)n3)CC2)(C(C)C)C1,,ClCCl,,CCN(CC)CC,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05665718,CCCNCCC.CN1Cc2c(-c3noc(CCl)n3)ncn2-c2cccc(Cl)c2C1=O>>CCCN(CCC)Cc1nc(-c2ncn3c2CN(C)C(=O)c2c(Cl)cccc2-3)no1,,CN(C)C=O,,,,test
US20140080813A1,CC(C)(C)OC(=O)N1CCNc2ccccc2C1.CC(C)=CC(=O)Cl>>CC(C)=CC(=O)N1CCN(C(=O)OC(C)(C)C)Cc2ccccc21,,ClCCl,,CCN(CC)CC,,test
US20120059162A1,CCOC(=O)c1cc(Cl)nnc1NN.O=CO>>CCOC(=O)c1cc(Cl)nn2cnnc12,,Cc1ccccc1,,,,test
US20130336920A1,CCSc1ccc(NC(=O)c2cccc(CSCCC(=O)OC(C)(C)C)c2)c(-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1>>CCSc1ccc(NC(=O)c2cccc(CSCCC(=O)O)c2)c(-c2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccn2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070185109A1,CCOC(=O)C1=C(c2ccccc2)c2ccc(OCCCc3ccccc3)cc2C1=O>>COC(=O)C1=C(c2ccccc2)c2ccc(OCCCc3ccccc3)cc2C1=O,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20050176699A1,CN1C(=O)C(N=C=S)N=C(c2ccccc2)c2cc(Cl)ccc21.Nc1cccc2cnccc12>>CN1C(=O)C(NC(=S)Nc2cccc3cnccc23)N=C(c2ccccc2)c2cc(Cl)ccc21,,ClCCl,,,,test
US20090118296A1,Nc1ccccc1S.O=C(O)c1ccc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)nn1>>FC(F)(F)c1ccccc1OC1CCN(c2ccc(-c3nc4ccccc4s3)nn2)CC1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20070254867A1,COc1cc([N+](=O)[O-])c(NC(C)=O)cc1OCOCC[Si](C)(C)C>>COc1cc([N+](=O)[O-])c(N)cc1OCOCC[Si](C)(C)C,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20070135631A1,COC(=O)C1(NC(=O)N[C@](Cc2ccccc2)(c2ccc(F)cc2)c2cc(F)cc(OC(F)(F)C(F)F)c2)CC1>>O=C(NC1(CO)CC1)N[C@](Cc1ccccc1)(c1ccc(F)cc1)c1cc(F)cc(OC(F)(F)C(F)F)c1,,C1CCOC1,CCOCC,Cl,[BH4-].[Li+],test
US20080176926A1,CCc1sc(C(=O)CCc2cc(C)c(OCCCO)c(C)c2)c2c1CC(C)(C)CC2.CS(=O)(=O)Cl>>CCc1sc(C(=O)CCc2cc(C)c(OCCCOS(C)(=O)=O)c(C)c2)c2c1CC(C)(C)CC2,,C1CCOC1,CCOCC,CCN(C(C)C)C(C)C,,test
US04420479,CC(C)S(=O)(=O)n1c(N)nc2ccc(C(O)(CC(=O)OC(C)(C)C)c3ccccc3)cc21>>CC(C)S(=O)(=O)n1c(N)nc2ccc(C(=CC(=O)O)c3ccccc3)cc21,,ClC(Cl)Cl,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US20090111794A1,Nc1ccccc1O.O=C(O)Cc1ccc(CO)cc1>>OCc1ccc(Cc2nc3ccccc3o2)cc1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20100305096A1,CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C=O)sc2n1>>CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CO)sc2n1,,ClCCCl,,CO,[BH4-].[Na+],test
US04000151,CCOC(C)(OCC)OCC.NNc1cc(-c2ccccc2Cl)c2cc(F)ccc2n1>>Cc1nnc2cc(-c3ccccc3Cl)c3cc(F)ccc3n12,,Cc1ccccc1C,,,,test
US20100240656A1,CCCCn1cnc(C(N)=O)c1N.O=C1CCC(=O)N1Br>>CCCCn1c(Br)nc(C(N)=O)c1N,,ClC(Cl)Cl,,,,test
US20070027163A1,OCc1cc2ccc(Cl)cc2[nH]1>>Cc1cc2ccc(Cl)cc2[nH]1,,ClCCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20120083488A1,COc1ccc2c(c1)C(C)(C)c1[nH]c3c(Br)c(C#N)ccc3c1C2=O>>CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21,,O,,Cl,c1ccncc1,test
US20110263626A1,COc1ccc(OCc2ccccc2)c(C(F)(F)F)c1>>COc1ccc(O)c(C(F)(F)F)c1,[Pd],CCOC(C)=O,,[H][H],,test
US20030083225A1,Cc1ccccc1.O=C(Cl)c1ccc([N+](=O)[O-])cc1.c1ccncc1>>O=C1CC2CC1C1CC=CC21,,Cc1ccccc1,,O,,test
US20090029976A1,CC(C)N1CCC(O)CC1.C[C@H]1CN(C(=O)c2cc3cc(O)ccc3o2)C[C@@H](C)O1>>CC(C)N1CCC(Oc2ccc3oc(C(=O)N4C[C@H](C)O[C@H](C)C4)cc3c2)CC1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20160159819A1,CCNN.CCOC(=O)C(=O)C1CCC(C)(C)C1=O>>CCn1nc(C)c2c1C(C)(C)CC2,,CCO,,O=C(O)C(=O)O,,test
US20030204100A1,CCCCCC1(CCCCC)Cc2c(cc(C(C)(C)C)c(OC(C)=O)c2C(C)(C)C)O1>>CCCCCC1(CCCCC)Cc2c(cc(C(C)(C)C)c(O)c2C(C)(C)C)O1,,CCCCCCC,,CC(C)(C)[O-].[K+],,test
US20100063067A1,CCOC(=O)C(C)=C1CCN(C(=O)OC(C)(C)C)CC1>>CCOC(=O)C(C)C1CCN(C(=O)OC(C)(C)C)CC1,,CCO,,,,test
US06002008,COc1cc2ncc(C#N)c(Cl)c2cc1OC.Nc1cc(Br)c(O)c(Br)c1>>COc1cc2ncc(C#N)c(Nc3cc(Br)c(O)c(Br)c3)c2cc1OC,,CCOCCO,,Cl,c1ccncc1,test
US20010027197A1,CSc1ncnc2cc(N)ncc12.C[C@@H](N)c1ccccc1>>C[C@@H](Nc1ncnc2cc(N)ncc12)c1ccccc1,,ClC(Cl)Cl,,O,,test
US20160143895A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c([C@@H]3CCCNC3)cc12.O=C(O)c1nc2ncccc2[nH]1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2cc(N(C)S(C)(=O)=O)c([C@@H]3CCCN(C(=O)c4nc5ncccc5[nH]4)C3)cc12,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,CCN=C=NCCCN(C)C,test
US20150045394A1,CCN(C(C)C)C(C)C.ClCCl.O=C(NC(Cc1ccccc1)C(O)C(=O)O)c1cccnc1-c1csc(-c2ccccc2)n1>>CONC(=O)C(O)C(Cc1ccccc1)NC(=O)c1cccnc1-c1csc(-c2ccccc2)n1,,ClCCl,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20040167165A1,Cc1cccc(C)c1.O=C(O)C12C=CC3SC3C1(S)S2>>Cc1cc(C)c2sc3ccccc3c(=O)c2c1,,O=S(=O)(O)O,,O,,test
US20130289033A1,O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(I)cc1.OB(O)c1ccccc1Cl>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(-c2ccccc2Cl)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20130296422A1,CC(C)(C)C(=O)Cl.OCCCCCCCO>>CC(C)(C)C(=O)OCCCCCCCO,,ClC(Cl)Cl,,O,c1ccncc1,test
US20020193536A1,CC(C)(C)c1cc(Br)c(O)c(C(C)(C)C)c1.C[Si](C)(C)Cl.ClP(c1ccccc1)c1ccccc1>>CC(C)(C)c1cc(P(c2ccccc2)c2ccccc2)c(O[Si](C)(C)C)c(C(C)(C)C)c1,,CCOCC,,CCCCCC,[Li]CCCC,test
US20090054494A1,CC(C)c1nnc(NS(=O)(=O)c2ccc(CCN)cc2)s1.COc1ccc(C(=O)Cl)cc1>>COc1ccc(C(=O)NCCc2ccc(S(=O)(=O)Nc3nnc(C(C)C)s3)cc2)cc1,,ClCCl,,Cl,,test
US03957803,CC(=O)Cl.CCCCC1C(=O)N(c2ccccc2)N(c2ccc(O)cc2)C1=O>>CC(=O)Oc1ccc(N2C(=O)CC(=O)N2c2ccccc2)cc1,,CC(=O)O,,,,test
US05705516,COc1ccc(CC(=O)NN)cc1.S=C=S>>COc1ccc(Cc2n[nH]c(=S)o2)cc1,,CCO,O,[K+].[OH-],,test
US20160143893A1,CC(=O)Cl.CS(=N)(=O)Cc1ccnc(Nc2cc(-c3ccc(F)c4ccoc34)c(F)cn2)c1>>CC(=O)N=S(C)(=O)Cc1ccnc(Nc2cc(-c3ccc(F)c4ccoc34)c(F)cn2)c1,,ClCCl,,CCN(CC)CC,,test
US20090069284A1,CC(C)(C)OC(=O)N1CC(C(=O)c2cc(F)cc(F)c2)C1.CC(C)(C)[Mg]Cl>>CC(C)(C)OC(=O)N1CC(C(O)(c2cc(F)cc(F)c2)C(C)(C)C)C1,,C1CCOC1,,[Cl-].[NH4+],,test
US20090264650A1,NC(=NO)c1ccc(F)cc1.O=C(O)CC1CCC(N2CCC(Cc3c(Cl)cccc3Cl)C2=O)CC1>>O=C1C(Cc2c(Cl)cccc2Cl)CCN1C1CCC(Cc2nc(-c3ccc(F)cc3)no2)CC1,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20080015238A1,CC(C)(C)OC(=O)C(C)(C)CC[C@H]1CCC[C@@H](O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)C1>>CC(C)(C)OC(=O)C(C)(C)CC[C@H]1CCC[C@@H](O)C1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100144876A1,CCN(CC)CC.CN(C)C(=O)CCCC#Cc1cccc(C(=O)O)c1.ClCCl>>CN(C)C(=O)CCCC#Cc1cccc(C(=O)NC2CC2)c1,,ClCCl,,CCN=C=NCCCN(C)C,,test
US20110118261A1,CN(C)[C@@H]1CCNC1.O=c1cc(OCc2ccc(Cl)cn2)ccn1-c1ccc(F)nc1>>CN(C)[C@@H]1CCN(c2ccc(-n3ccc(OCc4ccc(Cl)cn4)cc3=O)cn2)C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120083475A1,O=C(NCCc1c[nH]c2ccc(Cl)cc12)C(=O)NC(CO)c1ccccc1>>O=C(NCCc1c[nH]c2ccc(Cl)cc12)C1=NC(c2ccccc2)CO1,,C1CCOC1,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US20130172323A1,COc1ccc(CNN)cc1.O=C1OC(=O)C2CC12>>COc1ccc(CN2NC(=O)C3CC3C2=O)cc1,,CC#N,,,,test
US20100221182A1,FCCOc1ccc(N2CCNCC2)cc1.N=C(N)n1cccn1>>N=C(N)N1CCN(c2ccc(OCCF)cc2)CC1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20100227894A1,COC(=O)c1cc(C)cc([N+](=O)[O-])c1>>Cc1cc(C(=O)O)cc([N+](=O)[O-])c1,,C1CCOC1,CO,[Na+].[OH-],,test
US20160185785A1,C/C=C/C(=O)OCC.c1cc[nH]c1>>CC(CC(=O)O)n1cccc1,,CN(C)C=O,,[H-].[Na+],,test
US20160122319A1,CCN(CC)CC.Cc1ncc(CN2CC=C(c3ccccn3)CC2)cn1>>Nc1ncc(CN2CC=C(c3ccccn3)CC2)cn1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20090192162A1,CCOC(=O)COc1ccc(Sc2cc(C#Cc3ccc(S(C)(=O)=O)cc3)cc(Oc3ccc(C(F)(F)F)cn3)c2)cc1C>>Cc1cc(Sc2cc(C#Cc3ccc(S(C)(=O)=O)cc3)cc(Oc3ccc(C(F)(F)F)cn3)c2)ccc1OCC(=O)O,,CCO,,Cl,[Na+].[OH-],test
US20050107388A1,Clc1cc2ccccc2c(Cl)n1>>Clc1cc2ccccc2cn1,,CCO,,NN,O,test
US20030078271A1,CNC.Cc1ccc(Nc2cc(Cl)nc(N)n2)cc1>>Cc1ccc(Nc2cc(N(C)C)nc(N)n2)cc1,,CN(C)C=O,,CCN(CC)CC,Cl,test
US20090170908A1,O=CC1CCC2(CCC=CCC2)C1>>OCC1CCC2(CCC=CCC2)C1,,CO,,Cl,[BH4-].[Na+],test
US20100029782A1,CCOC(=O)CCc1cc(O)c(F)c(F)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)CCc1cc(F)c(F)c(OS(=O)(=O)C(F)(F)F)c1,,ClCCl,,CCN(CC)CC,,test
US20150158826A1,CC(C)(C)C(=O)Nc1cccc(C(O)c2ccc3ncc(Cl)nc3c2)c1>>CC(C)(C)C(=O)Nc1cccc(C(=O)c2ccc3ncc(Cl)nc3c2)c1,O=[Mn]=O,ClCCl,,,,test
US20070191336A1,CC(C)(C)c1cc(NC(=O)Nc2ccc(Cl)cc2)n(-c2ccc(OCc3ccccc3)cc2)n1>>CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(-c2ccc(O)cc2)n1,[Pd],CO,,,,test
US20060166997A1,CC(=O)Oc1ccccc1OC(C)C.ClI>>CC(=O)Oc1cc(I)ccc1OC(C)C,,CCOCC,ClCCl,,,test
US04640915,COC(C[C@H]1NC(=O)[C@@H]1C(C)(C)OC)OC>>COC(C)(C)[C@H]1C(=O)N[C@@H]1CC=O,,CC(=O)O,,,,test
US20060135556A1,COCc1nnc(S)n1-c1ccccc1.O=C(CCl)Nc1ccccc1Cl>>COCc1nnc(SCC(=O)Nc2ccccc2Cl)n1-c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100190806A1,COc1cccc(N)c1.Nc1nc(Cl)c2[nH]cnc2n1>>COc1cccc(Nc2nc(N)nc3nc[nH]c23)c1,,CCCCO,,CCN(CC)CC,,test
US20130324551A1,CC(C)(C)OC(=O)OC(=O)[O-].NC(=O)C1CCNCC1>>CC(C)(C)OC(=O)N1CCC(C(N)=O)CC1,CN(C)c1ccncc1,CC#N,,,,test
US20160108039A1,CC(C)(C)OC(=O)N1CCC1CNCc1ccccc1.COC(=O)C(C)Br>>COC(=O)C(C)N(Cc1ccccc1)CC1CCN1C(=O)OC(C)(C)C,,ClCCl,O,CCN(CC)CC,,test
US20030083333A1,CC(C)(C)OC(=O)Nc1ccc(O)c2ccccc12.O=c1cc(Cl)cco1>>CC(C)(C)OC(=O)Nc1ccc(Oc2ccoc(=O)c2)c2ccccc12,,C1CCOC1,,[H-].[Na+],,test
US20110059999A1,C=COCC.O=C1CCC(C(O)COc2ccccc2)CC1>>CCOC(C)OC(COc1ccccc1)C1CCC(=O)CC1,,ClCCl,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20080269213A1,CC(C)C(=O)Cl.CN(C)Cc1ccc(C(N)Cc2cc(Cl)c3cccnc3c2OCc2ccccc2)o1>>CC(C)C(=O)NC(Cc1cc(Cl)c2cccnc2c1OCc1ccccc1)c1ccc(CN(C)C)o1,,C1CCOC1,,CCN(CC)CC,,test
US04855442,CC1(C)C(=O)N(Cl)C(=O)N1Cl.Cn1nc(O)cc1C(F)(F)F>>Cn1nc(O)c(Cl)c1C(F)(F)F,,CCOCC,,,,test
US04859692,CCCCCC(=O)Cl.COC(=O)c1cccc(CN2CCOc3ccc(N)cc32)c1>>CCCCCC(=O)Nc1ccc2c(c1)N(Cc1cccc(C(=O)OC)c1)CCO2,,ClCCl,,CN1CCOCC1,,test
US20120149662A1,CC(=O)c1c[nH]c(C(=O)C(Cl)(Cl)Cl)c1.O=[N+]([O-])O>>CC(=O)c1cc(C(=O)C(Cl)(Cl)Cl)[nH]c1[N+](=O)[O-],,O=S(=O)(O)O,,,,test
US20140018313A1,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1ccc2c3c(ccc2c1)-c1ccc(Br)cc1CO3>>O=S(=O)(Oc1ccc2c3c(ccc2c1)-c1ccc(Br)cc1CO3)C(F)(F)F,,ClCCl,,Cl,c1ccncc1,test
US20080221148A1,COc1cc(F)c(C=O)cc1OC.ClCc1nc2cc(Cl)c(Cl)cc2[nH]1>>COc1cc(C=O)c(F)cc1OCc1nc2cc(Cl)c(Cl)cc2[nH]1,,CN(C)C=O,,[H-].[Na+],,test
US20030078251A1,CCOC(=O)CC(=O)Cc1ccc(OC)c([N+](=O)[O-])c1>>CCOC(=O)CC(O)Cc1ccc(OC)c([N+](=O)[O-])c1,,CCOC(C)=O,CO,Cl,[BH4-].[Na+],test
US20140334027A1,CC(=O)c1ccc(-n2c3ccccc3c3cc(C(=O)c4c(C)cc(C)cc4C)c4ccccc4c32)cc1.CC(C)CC(=O)Cl>>CC(=O)c1ccc(-n2c3ccc(C(=O)CC(C)C)cc3c3cc(C(=O)c4c(C)cc(C)cc4C)c4ccccc4c32)cc1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20080009530A1,CCOC(=O)/C=C/c1ccc(O)c(C)c1OCc1ccc(Cl)cc1Cl.COCCBr>>CCOC(=O)/C=C/c1ccc(OCCOC)c(C)c1OCc1ccc(Cl)cc1Cl,,CN(C)C=O,O,[I-].[K+],O=C([O-])O.[Na+],test
US20100261673A1,C1CCOC1.N/C(=N\O)c1ccc(Oc2ccc(C(F)(F)F)cc2)cc1>>Cc1nc(-c2ccc(Oc3ccc(C(F)(F)F)cc3)cc2)no1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150344490A1,COc1ccc(Nc2ccncc2[N+](=O)[O-])c(C)c1>>COc1ccc(Nc2ccncc2N)c(C)c1,[Pd],CO,,[H][H],,test
US20090197871A1,CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)O)c1.Cc1ccc(CN)cc1Br>>CCc1nc2c(cnn2CC)c(NC2CCOCC2)c1CNC(=O)c1cccc(C(=O)NCc2ccc(C)c(Br)c2)c1,,ClCCl,,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US07563786B2,C#Cc1ccc(C(=O)O)s1.Cc1cc(NC(=O)C2(N)CCOC2)ccc1N1CCOCC1=O>>C#Cc1ccc(C(=O)NC2(C(=O)Nc3ccc(N4CCOCC4=O)c(C)c3)CCOC2)s1,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20130150343A1,CN1CCN(Cc2nnc3ccc(O[C@@H]4CC[C@H](N)c5ccccc54)cn23)CC1.Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)OCC(Cl)(Cl)Cl)cc1.O=CO>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(CN5CCN(C)CC5)n4c3)c3ccccc32)cc1.O=CO,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20070093521A1,CCOc1cc(C=O)cc(OCC)c1-n1cccc1.COC(=O)CCCOc1cccc2nc(NC3CCNCC3)oc12>>CCOc1cc(CN2CCC(Nc3nc4cccc(OCCCC(=O)OC)c4o3)CC2)cc(OCC)c1-n1cccc1,,CC(=O)O,CCO,CCN(C(C)C)C(C)C,[BH3-]C#N.[Na+],test
US20120271048A1,Nc1cc(-n2ccc3ccc(-c4cccc([N+](=O)[O-])c4)cc32)ncn1>>Nc1cccc(-c2ccc3ccn(-c4cc(N)ncn4)c3c2)c1,[Ni],C1COCCO1,CO,,,test
US20090227548A1,O=Cc1ccc(CBr)cc1.Oc1ccc(S)cc1>>O=Cc1ccc(CSc2ccc(O)cc2)cc1,,C1COCCO1,O,CCN(CC)CC,,test
US20090111800A1,Cc1cc(OCc2ccccc2)cc(C)c1C=O>>Cc1cc(OCc2ccccc2)cc(C)c1CO,,CO,,[BH4-].[Na+],,test
US20090298807A1,Cc1ccc(C(=O)N2CC(F)(F)OC3(CCN(C(=O)OC(C)(C)C)CC3)C2)s1.O=C(O)C(F)(F)F>>Cc1ccc(C(=O)N2CC(F)(F)OC3(CCNCC3)C2)s1.O=C(O)C(F)(F)F,,ClCCl,,Cc1ccccc1,,test
US20150218181A1,CC(C)(C)OC(=O)N1CCn2c(Br)nnc2C1>>Brc1nnc2n1CCNC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130184479A1,COc1cc(Br)cc(OC)c1.ClP(c1ccccc1)c1ccccc1.OO>>COc1cc(OC)cc(P(=O)(c2ccccc2)c2ccccc2)c1,II,C1CCOC1,O,[Mg],,test
US20050020584A1,COc1ccc(C#N)cc1Br>>CONCc1cccc(Br)c1,,C1CCOC1,,B,CO,test
US20140005393A1,O=[N+]([O-])c1cc(Cl)[n+]([O-])cc1Cl>>O=[N+]([O-])c1cc(Cl)ncc1Cl,,ClC(Cl)Cl,,O=P(Cl)(Cl)Cl,O=C([O-])O.[Na+],test
US20020103192A1,COC(=O)CCCCCCC(=O)C(F)(F)F>>O=C(O)CCCCCCC(=O)C(F)(F)F,,C1CCOC1,,[Li+].[OH-],,test
US20110144105A1,CS(=O)(=O)c1ccc(C(=C[C@@H]2CCCCO2)c2cc3cccnc3[nH]2)cc1>>CS(=O)(=O)c1ccc(C(CC2CCCCO2)c2cc3cccnc3[nH]2)cc1,[Pd],CO,,,,test
US20110301082A1,COC(=O)c1cc(Br)c([Si](C)(C)C)c(F)c1F.O=C(O)Cc1ccc(Cl)cc1>>C[Si](C)(C)c1c(Br)cc(C(=O)Cc2ccc(Cl)cc2)c(F)c1F,,C1CCOC1,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US05296495,CCOC(=O)c1ccccc1C=Cc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1>>CCOC(=O)c1ccccc1CCc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1,[Pd],CO,,,,test
US20150166480A1,CCC(O)(CC)CN1CCC(COc2ccc(Br)cc2C#N)CC1.CCN(CC)S(F)(F)F>>CCC(F)(CC)CN1CCC(COc2ccc(Br)cc2C#N)CC1,,ClCCl,,O,,test
US05663164,CON=C(C(=O)NC1C(=O)N2C(C(=O)OC(C)(C)C)=C(SCC(=O)OC(C)(C)C)SCC12)c1csc(NC(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(SCC(=O)O)SCC12)c1csc(N)n1,,O=CO,,,,test
US20030013886A1,Cc1nc2ccccc2[nH]1.Fc1ccccn1>>Cc1nc2ccccc2n1-c1ccccn1,,CC(=O)N(C)C,,[H-].[Na+],,test
US20150126490A1,Br.Nc1cc(N2CCOCC2)cnc1[N+](=O)[O-]>>O=[N+]([O-])c1ncc(N2CCOCC2)cc1Br,,O,,O=N[O-].[Na+],,test
US20080081817A1,COC1CCCC(C(=O)O)C1>>COC1CCCC(CO)C1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20060052277A1,CC(=CC(C)C)C(=O)O.[Li]C>>CC(=O)C(C)=CC(C)C,,CCOCC,,Cl,,test
US06306891B1,CCOC(=O)C1CCC(c2ccccc2)=N1>>O=C(O)c1ccc(-c2ccccc2)[nH]1,,ClCCl,,N#CC1=C(C#N)C(=O)C(Cl)=C(Cl)C1=O,,test
US06608084B1,CCOC(=O)CC(C)c1ccc2c(c1)CCN2C(=O)Cc1ccc(NC(=O)Nc2ccccc2C)cc1>>Cc1ccccc1NC(=O)Nc1ccc(CC(=O)N2CCc3cc(C(C)CC(=O)O)ccc32)cc1,,C1CCOC1,,CO,[Na+].[OH-],test
US06087509,C[Si](C)(C)OCCCCI.N#Cc1ccc(N2C(=O)NC3(CCCCC3)C2=O)cc1C(F)(F)F>>N#Cc1ccc(N2C(=O)N(CCCCO)C3(CCCCC3)C2=O)cc1C(F)(F)F,,CN(C)C=O,,[H][H],[H-].[Na+],test
US20090082372A1,CCOC(=O)C(N)Cc1n[nH]c2c(F)cccc12>>NC(CO)Cc1n[nH]c2c(F)cccc12,,C1CCOC1,CCO,[BH4-].[Li+],,test
US04875924,CCOC(=O)c1nn(-c2ccc(OC(F)(F)F)cc2)c2cccc(F)c2c1=O>>O=C(O)c1nn(-c2ccc(OC(F)(F)F)cc2)c2cccc(F)c2c1=O,,O,,CCO,[K+].[OH-],test
US20090275567A1,C1COCCN1.Cc1ncc(-c2nc(NC3CCNCC3)ncc2Cl)n1C(C)C.O=S(=O)(Cl)CCCl>>Cc1ncc(-c2nc(NC3CCN(S(=O)(=O)CCN4CCOCC4)CC3)ncc2Cl)n1C(C)C,,ClCCl,,,,test
US20100016340A1,Cc1ccc(Cl)c(Br)c1.OB(O)c1ccccc1>>Cc1ccc(Cl)c(-c2ccccc2)c1,,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US05654299,CN(C[C@@H](CC=O)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1.CSc1ccc(C2CCNCC2)cc1.ClCCl>>CSc1ccc(C2CCN(CC[C@H](CN(C)C(=O)c3ccccc3)c3ccc(Cl)c(Cl)c3)CC2)cc1.Cl,,O,,CO,,test
US20050245513A1,CC(C)OB(OC(C)C)OC(C)C.O=C(O)c1ccc(F)c(Br)c1>>O=C(O)c1ccc(F)c(B(O)O)c1,,C1CCOC1,Cl,[Li]CCCC,,test
US20130150407A1,COC(=O)Cc1cc2ccc(F)cc2c(C2CCN(S(=O)(=O)Cc3ccccc3)CC2)c1C>>Cc1c(CC(=O)O)cc2ccc(F)cc2c1C1CCN(S(=O)(=O)Cc2ccccc2)CC1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20050096322A1,CSc1cccc(-c2nnc3ccc(N4CCCCC4)nn23)c1.O=C(OO)c1cccc(Cl)c1>>CS(=O)(=O)c1cccc(-c2nnc3ccc(N4CCCCC4)nn23)c1,,ClCCl,,O,,test
US20140228376A1,CCOC(=O)c1nc(C(F)(F)F)c(C(F)(F)F)nc1N.NN>>NNC(=O)c1nc(C(F)(F)F)c(C(F)(F)F)nc1N,,CO,O,Cl,,test
US05922715,ClCCCl.Nc1c(O)cccc1[N+](=O)[O-]>>Nc1c(OCCCl)cccc1[N+](=O)[O-],,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06300363B1,CC(=O)Cl.COC(=O)c1cccc(C(=O)c2[nH]c3cc(Cl)ccc3c2N)c1>>COC(=O)c1cccc(C(=O)c2[nH]c3cc(Cl)ccc3c2NC(C)=O)c1,,CCOC(C)=O,,,,test
US20030171411A1,COC(=O)C(O)c1ccc(Br)cc1.Cc1ccc(S)cc1.Nc1ccccn1>>Cc1ccc(SC(C(=O)Nc2ccccn2)c2ccc(Br)cc2)cc1,,C1CCOC1,,,,test
US04576749,Cc1ccccc1.O=C(Cl)Cl.O=C(N[C@H]1CNC1=O)OCc1ccccc1.O=C(O)[C@@H]1CCN1>>O=C(N[C@H]1CN(C(=O)N2CC[C@H]2C(=O)OCc2ccccc2)C1=O)OCc1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20110015230A1,CCCOc1cc(C(F)(F)F)ccc1C=CC(=O)OC>>CCCOc1cc(C(F)(F)F)ccc1C=CC(=O)O,,C1CCOC1,CO,[Li+].[OH-],,test
US06362177B1,Cc1noc(C)c1CN1CC[C@@H](NC(=O)CN)C1.O=C(Cl)c1cc(F)cc(C(F)(F)F)c1>>Cc1noc(C)c1CN1CC[C@@H](NC(=O)CNC(=O)c2cc(F)cc(C(F)(F)F)c2)C1,,ClC(Cl)Cl,ClCCl,CO,,test
US04073912,O=C(O)c1ccccc1I.Oc1ccc2ccccc2c1>>O=C(O)c1ccccc1Oc1ccc2ccccc2c1,,c1ccncc1,,O=C([O-])[O-].[K+].[K+],,test
US20150158865A1,C1CN[C@@H]2CCCN[C@@H]2C1.CN(C)C(=O)Cl.N#Cc1ncc(Cl)nc1Cl>>CN(C)C(=O)N1CCC[C@@H]2[C@H]1CCCN2c1cnc(C#N)c(Cl)n1,,CCOC(C)=O,CN1CCCC1=O,CCN(C(C)C)C(C)C,,test
US20160244451A1,C=Cc1ncc(Br)cn1.CNC>>CN(C)CCc1ncc(Br)cn1,,CO,,,,test
US20020193578A1,CCOC1(c2ccc(C#Cc3ccc(CC(=O)OC)cc3)cc2C(C)C)CC1>>CCOC1(c2ccc(C#Cc3ccc(CC(=O)O)cc3)cc2C(C)C)CC1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20080132551A1,O=C(Nc1cc(C(F)(F)F)on1)c1ccccc1>>Nc1cc(C(F)(F)F)on1,,OCCO,,Cl,,test
US20110112063A1,Cc1cc(Nc2nc(Nc3cc(C)c(C4CCNCC4)cc3C)ncc2Cl)n[nH]1.O=S(=O)(Cl)CCCCl>>Cc1cc(Nc2nc(Nc3cc(C)c(C4CCN(S(=O)(=O)CCCCl)CC4)cc3C)ncc2Cl)n[nH]1,,ClCCl,,CCOC(C)=O,,test
US20160194316A1,COc1c(C#N)c(C)nn1C>>COc1c(CN)c(C)nn1C,[Ni],CO,,N,,test
US20110144129A1,CC[C@]1(C(=O)N2C[C@@H]3C[C@H]2CN3C(=O)OC(C)(C)C)C=C[C@@H](N)C1>>CC[C@]1(C(=O)N2C[C@@H]3C[C@H]2CN3C(=O)OC(C)(C)C)CC[C@@H](N)C1,[Pd],CO,,[H][H],,test
US20070129334A1,CS(=O)(=O)Cl.Nc1ncnc2c1nc(Sc1nc3cccc(Cl)c3s1)n2CCO>>CS(=O)(=O)OCCn1c(Sc2nc3cccc(Cl)c3s2)nc2c(N)ncnc21,,CN(C)C=O,,CCN(CC)CC,,test
US20020040020A1,CO.CS(=O)(=O)N1CCc2c(c(-c3ccc(C(F)(F)F)cc3)nn2CCCN2CCN(c3c(N)cccc3Cl)CC2)C1.C[Si](C)(C)N=C=O>>CNC(=O)Nc1cccc(Cl)c1N1CCN(CCCn2nc(-c3ccc(C(F)(F)F)cc3)c3c2CCN(S(C)(=O)=O)C3)CC1,,ClCCl,,,,test
US20060084802A1,CCCCCOC(=O)c1cc(N)ncc1Sc1ccc(S(=O)(=O)N2CCCCC2)cc1.O=S(=O)(Cl)c1ccc(Cl)cc1Cl>>CCCCCOC(=O)c1cc(NS(=O)(=O)c2ccc(Cl)cc2Cl)ncc1Sc1ccc(S(=O)(=O)N2CCCCC2)cc1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20040077829A1,CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)O.Fc1nc(F)nc(F)n1>>CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)F,,ClCCl,,c1ccncc1,,test
US20090275581A1,Cc1cccc(-c2c(F)cccc2C(=O)[C@H]2CN(C(=O)OC(C)(C)C)CCO2)c1>>Cc1cccc(-c2c(F)cccc2C(O)[C@H]2CN(C(=O)OC(C)(C)C)CCO2)c1,,CCO,,[BH4-].[Na+],,test
US20090270460A1,CNc1c(C)cc(O[Si](C(C)C)(C(C)C)C(C)C)cc1F.COC(=O)c1ccc(C=O)cc1C>>COC(=O)c1ccc(CN(C)c2c(C)cc(O[Si](C(C)C)(C(C)C)C(C)C)cc2F)cc1C,,CC(=O)O,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US03940259,CCc1cccc(CC)c1N.ClCC1OCCCO1>>CCc1cccc(CC)c1NCC1OCCCO1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120263670A1,CCOC(=O)/C(C)=C/c1cc(F)c(F)c(F)c1.Oc1ccccc1>>CCOC(=O)/C(C)=C/c1cc(F)c(Oc2ccccc2)c(F)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20140138295A1,C=CC(=O)NC(C)C.NCCN>>C=CC(=O)NC(C)C.NCCN,,CC(C)=O,,,,test
US20140323464A1,Cn1c(=O)c(-c2ccccc2Cl)cc2cnc(Nc3cccc(N)c3)nc21.N#CC(=CC1CC1)C(=O)O>>Cn1c(=O)c(-c2ccccc2Cl)cc2cnc(Nc3cccc(NC(=O)C(C#N)=CC4CC4)c3)nc21,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080064682A1,CI.O=C(c1cc(-c2ccc(CO)cn2)n(-c2cccnc2)n1)N1CCC(F)(F)CC1>>COCc1ccc(-c2cc(C(=O)N3CCC(F)(F)CC3)nn2-c2cccnc2)nc1,,CN(C)C=O,,[H-].[Na+],,test
US20120214803A1,CC(=O)c1ccc2cccnc2c1N.CNS(=O)(=O)Cl>>CC1c2ccc3cccnc3c2NS(=O)(=O)N1C,,c1ccncc1,,[BH4-].[Na+],,test
US20020025968A1,NC(=O)c1cc(Cl)ccc1N.O=C(Cl)Cl>>O=c1[nH]c(=O)c2cc(Cl)ccc2[nH]1,,C1CCOC1,,,,test
US20100004219A1,COC(O[Si](C)(C)C)=C(C)C.OC(c1cccc(F)c1)c1ccc(Br)s1>>COC(=O)C(C)(C)C(c1cccc(F)c1)c1ccc(Br)s1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20080171772A1,CCOC(=O)c1ccc(I)cc1.O=[N+]([O-])O>>CCOC(=O)c1ccc(I)c([N+](=O)[O-])c1,,O=S(=O)(O)O,,,,test
US20160229814A1,Nc1ccc([N+](=O)[O-])cc1C(=O)NCC1COC1.O=C(n1ccnc1)n1ccnc1>>O=c1[nH]c2ccc([N+](=O)[O-])cc2c(=O)n1CC1COC1,,C1CCOC1,,O,,test
US20100158843A1,C=CCc1ccc(O)c(OC)c1.CS(=O)(=O)Cl>>C=CCc1ccc(OS(C)(=O)=O)c(OC)c1,,CCOC(C)=O,ClCCl,CCN(CC)CC,O,test
US20040014962A1,CS(=O)(=O)Cl.O=C(OCc1ccc([N+](=O)[O-])cc1)c1csc(N2CC(O)C2)n1>>CS(=O)(=O)OC1CN(c2nc(C(=O)OCc3ccc([N+](=O)[O-])cc3)cs2)C1,,ClCCl,,CCN(CC)CC,,test
US05221742,CC(CC(=O)O)C(=O)c1ccc2c(c1)OCC(=O)N2.CNN>>CC1CC(=O)N(C)N=C1c1ccc2c(c1)OCC(=O)N2,,CCO,,,,test
US06028032,BrP(Br)Br.CC(C)(C(=O)OCc1ccccc1)N1COC(CO)=C(c2ccccc2)C1=O>>CC(C)(C(=O)OCc1ccccc1)N1COC(CBr)=C(c2ccccc2)C1=O,,C1CCOC1,CCOCC,,,test
US20150315198A1,COC1=NCCC1.Cc1ccc(C(=O)O)c(N)c1>>Cc1ccc2c(=O)n3c(nc2c1)CCC3,,O,,CN(C)C=O,,test
US20060014826A1,CC1(C)CC(=O)CC(=O)O1.O=C=Nc1ccc(C(F)(F)F)cc1>>CC1(C)CC(=O)C(C(=O)Nc2ccc(C(F)(F)F)cc2)C(=O)O1,,CN(C)C=O,,CCN(CC)CC,,test
US20090105219A1,CN1C(=O)Cn2c(=O)[nH]c3cccc1c32.N#CCBr>>CN1C(=O)Cn2c(=O)n(CC#N)c3cccc1c32,,CN(C)C=O,,[H-].[Na+],,test
US20110039821A1,CC(C)Oc1cc(C(=O)OC(C)(C)C)cc2c1CC(COc1ccccc1)O2.Cn1ccc(N)n1>>CC(C)Oc1cc(C(=O)Nc2ccn(C)n2)cc2c1CC(COc1ccccc1)O2,,O,,,,test
US05075313,COC(=O)c1ccccc1N.O=C(O)CCc1c[nH]c2ccccc12>>COC(=O)c1ccccc1NC(=O)CCc1c[nH]c2ccccc12,,C1CCOC1,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20060116383A1,CCOC(=O)/C=C(\c1ccc(CC)cc1)n1cnc2ccccc21>>CCc1ccc(/C(=C\C(=O)O)n2cnc3ccccc32)cc1,,Cl,,,,test
US04870076,CCOC(=O)C=[N+]=[N-].Cn1cccc1CCNS(=O)(=O)c1ccc(F)cc1>>CCOC(=O)Cc1ccc(CCNS(=O)(=O)c2ccc(F)cc2)n1C,Cl[Cu],ClCCCl,,,,test
US20080096861A1,CC(C)(C)OC(=O)N1CCC[C@H](CN)C1.O=[N+]([O-])c1ccccc1F>>CC(C)(C)OC(=O)N1CCC[C@H](CNc2ccccc2[N+](=O)[O-])C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080071114A1,O[C@H](CCl)c1ccc(F)c(F)c1>>Fc1ccc([C@H]2CO2)cc1F,,O,,Cc1ccccc1,[Na+].[OH-],test
US20100120739A1,CCOC(=O)C=Cc1ccc2ncccc2c1>>CCOC(=O)CCc1ccc2ncccc2c1,[Pd],CO,,,,test
US20100267748A1,NCCO.O=C(O)c1ccc2ncc(Cc3ccc(Cl)c(Cl)c3)c(=O)n2c1>>O=C(NCCO)c1ccc2ncc(Cc3ccc(Cl)c(Cl)c3)c(=O)n2c1,,CN(C)C=O,ClCCl,O=C(n1ccnc1)n1ccnc1,,test
US20110053940A1,CCC(=O)NCCc1cc(Cl)c(Cl)c(CO)c1>>CCC(=O)NCCc1cc(Cl)c(Cl)c(C=O)c1,,ClCCl,,O=C([O-])O.[Na+],,test
US05936109,C=C(NC(C)=O)C(=O)OC>>COC(=O)[C@@H](C)NC(C)=O,,CO,,O=O,,test
US20110207714A1,CC(C)(C)OC(=O)N1CC(Oc2cc(Cl)ccc2OC2Cc3ccc(F)cc3C2=O)C1.NO>>CC(C)(C)OC(=O)N1CC(Oc2cc(Cl)ccc2OC2Cc3ccccc3C2=NO)C1,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20050277662A1,O=C1NCc2ccncc21>>O=C1NCC2CCNCC12,O=[Pt]=O,CC(=O)O,,C1COCCO1,Cl,test
US20120302599A1,BrCc1ccccc1.CCOC(=O)c1cn[nH]c1[N+](=O)[O-]>>CCOC(=O)c1cn(Cc2ccccc2)nc1[N+](=O)[O-],,CCOC(C)=O,CN(C)C=O,[I-].[K+],,test
US20050192295A1,C#CC(=O)c1c(-c2ccc(OC)cc2)nn2ccc(Cl)cc12.CSC(=N)N>>COc1ccc(-c2nn3ccc(Cl)cc3c2-c2ccnc(SC)n2)cc1,,CCO,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20070185324A1,CNc1ncc2cc(-c3c(C)ccc(C(=S)Nc4cccc(OC(C)C)c4)c3F)ccc2n1.NN>>CNc1ncc2cc(-c3c(C)ccc4c(Nc5cccc(OC(C)C)c5)n[nH]c34)ccc2n1,,CCCCO,,O,,test
US20090221644A1,BrC(Br)(Br)Br.CSc1ccc2oc(CO)cc2c1>>CSc1ccc2oc(CBr)cc2c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20110172202A1,CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4N)no2)cc1C#N.ClCC1CO1>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CC[C@H]4NCC(O)CCl)no2)cc1C#N,,O,,CC(C)O,,test
US04138567,O=C(CCCCl)c1ccc(F)cc1.O=C1Nc2ccccc2N2CCNCC12>>O=C(CCCN1CCN2c3ccccc3NC(=O)C2C1)c1ccc(F)cc1,,CC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20090221583A1,CCOC(=O)C(=O)CC(=O)c1ccccc1.NN>>COC(=O)c1cc(-c2ccccc2)[nH]n1,,CO,,O,,test
US20050085518A1,CCOC(=O)N1CCC(NS(=O)(=O)c2ccc(C(C)O)c3ccccc23)CC1>>CCOC(=O)N1CCC(NS(=O)(=O)c2ccc(C(C)=O)c3ccccc23)CC1,,ClCCl,,CCN(CC)CC,CS(C)=O,test
US20120208798A1,CNCc1ccccc1.ClCCn1cc(Br)cn1>>CN(CCn1cc(Br)cn1)Cc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120135352A1,Cc1cc(Br)ccc1O.Cc1cc(C(c2ccc(O)c(C)c2)C2CC3C=CC2C3)ccc1O>>Cc1cc(C2CC3CC2CC3C(c2ccc(O)c(C)c2)c2ccc(O)c(C)c2)ccc1O,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,O=CO,test
US20060128790A1,CON.Cc1c(C)c2c(c(C)c1O)CC(CO)C1(CCC1)O2>>CON=CC1=Cc2c(cc(C)c(O)c2C)OC12CCC2,,c1ccncc1,,Cl,,test
US20070072847A1,CCOC(=O)CN1CCC(N2CCN(C(=O)[C@@H](Cc3cc(C)c(OCc4ccccc4)c(C)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1>>CCOC(=O)CN1CCC(N2CCN(C(=O)[C@@H](Cc3cc(C)c(O)c(C)c3)OC(=O)N3CCC(N4CCc5ccccc5NC4=O)CC3)CC2)CC1,[Pd],CCO,,[H][H],,test
US20110230458A1,CCCCc1nnc(OCC[C@H]2CCCCN2)cc1-c1ccc(OC2CCCCC2)cc1.Cl.Cl.ClCCl>>CCCCc1nnc(OCC[C@H]2CCCCN2C)cc1-c1ccc(OC2CCCCC2)cc1.Cl.Cl,,ClCCl,,CCOCC,Cl,test
US05962531,CI.CS(=O)(=O)c1ccc2c(C(=O)c3ccc(F)cc3)c(O)ccc2c1>>COc1ccc2cc(S(C)(=O)=O)ccc2c1C(=O)c1ccc(F)cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130184284A1,N#Cc1cccc(C=O)c1.[C-]#[N+]CS(=O)(=O)c1ccc(C)cc1>>N#Cc1cccc(-c2cnco2)c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US05270327,C1CCC(CN2CCCC2)NC1.O=C1CC(C(=O)Cl)c2ccc(Cl)c(Cl)c21>>Cl.O=C1CC(C(=O)N2CCCCC2CN2CCCC2)c2ccc(Cl)c(Cl)c21,,CCN(CC)CC,,,,test
US20040220193A1,COC(OC)c1cc(Br)cs1.N#C[Cu]C#N>>N#Cc1csc(C=O)c1,,CC(=O)O,CN(C)C=O,CCOC(C)=O,,test
US20090226377A1,CN(C)C=Nc1ccc(Br)cc1C#N.Cc1ccc(O)cc1N>>Cc1ccc(O)cc1Nc1ncnc2ccc(Br)cc12,,CC(=O)O,,O,,test
US05212195,Brc1ccc(Cc2cc3ccccc3[nH]2)cc1.CCCCI>>CCCCn1c(Cc2ccc(Br)cc2)cc2ccccc21,,CN(C)C=O,,Cl,[H-].[Na+],test
US20030144263A1,CC(C)(C)[Si](C)(C)OC1CN(c2ccc(N3C[C@H](CO)OC3=O)cc2F)C1.Oc1ccon1>>CC(C)(C)[Si](C)(C)OC1CN(c2ccc(N3C[C@H](COc4ccon4)OC3=O)cc2F)C1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20060069077A1,CC(C)(C)[Si](C)(C)Cl.O=C1N[C@H](CO)CN2CCC[C@@H]12>>CC(C)(C)[Si](C)(C)OC[C@@H]1CN2CCC[C@H]2C(=O)N1,CN(C)c1ccncc1,CN(C)C=O,,CCN(CC)CC,,test
US20080188521A1,C#CC(O)(CC)CC.[N-]=[N+]=NCc1ccc2c(-c3cccc(F)c3)cc(=O)oc2c1>>CCC(O)(CC)c1cn(Cc2ccc3c(-c4cccc(F)c4)cc(=O)oc3c2)nn1,I[Cu]I,CCOC(C)=O,,C1CCOC1,,test
US20060173048A1,C=O.CCN.O=C(C(=NO)c1ccncc1)c1ccc(Cl)cc1>>CCn1c(O)nc(-c2ccncc2)c1-c1ccc(Cl)cc1,,CC(=O)O,,N,,test
US06008230,O=C(Nc1cccc2c(Cl)c(Br)cnc12)c1c(Cl)cccc1Cl.Sc1ncc[nH]1>>O=C(Nc1cccc2c(Sc3ncc[nH]3)c(Br)cnc12)c1c(Cl)cccc1Cl,,CN1CCCC1=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040214822A1,CN(C)C1(C#N)CCC2(CC1)OCCO2.Fc1cccc(CCl)c1>>CN(C)C1(Cc2cccc(F)c2)CCC2(CC1)OCCO2,,CCOCC,,[Mg],[Cl-].[NH4+],test
US20060235030A1,CCN(CC)CCCN.Cc1ccc(C(=O)Nc2ccc(F)cc2)cc1-c1nc(S(C)=O)nc2c1CNC(=O)N2c1c(F)cccc1F>>CCN(CC)CCCNc1nc(-c2cc(C(=O)Nc3ccc(F)cc3)ccc2C)c2c(n1)N(c1c(F)cccc1F)C(=O)NC2,,C1CCOC1,,,,test
US20110201650A1,COc1ccc(-n2nc(C3(O)CCC4(CC3)OCCO4)cc2-c2ccc(C)cc2)cc1>>COc1ccc(-n2nc(C3(O)CCC(=O)CC3)cc2-c2ccc(C)cc2)cc1,,C1CCOC1,Cl,[Na+].[OH-],,test
US20140100229A1,COC(=O)C(=O)C(C)(C)C(=O)OC.N=C(NN)c1nn(CC2CCCC2)c2ncc(F)cc12>>COC(=O)C(C)(C)c1nnc(-c2nn(CC3CCCC3)c3ncc(F)cc23)nc1O,,CCO,,,,test
US20120329780A1,COC(=O)c1cccc(-c2nc(Cl)c3nn(Cc4ccc(OC)cc4)cc3n2)c1.Nc1ccc2c(c1)NC(=O)CCC2>>O=C1CCCc2ccc(Nc3nc(-c4cccc(C(=O)O)c4)nc4cn[nH]c34)cc2N1,C1COCCO1,CO,,Cl,,test
US20140112945A1,COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4ccc(F)cc4)NC(=O)OC(C)(C)C)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC.Cl>>COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)Cc4ccc(F)cc4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC.Cl,,C1COCCO1,,CCOCC,,test
US20130115190A1,C=CCCC(C)C[C@@H](CC)C(N=C(c1ccccc1)c1ccccc1)C(=O)OCC.Cl>>C=CCCC(C)C[C@@H](CC)C(N)C(=O)OCC.Cl,,CCOCC,,,,test
US20030144338A1,CCCCCCCCCCCCN.COc1ccc(C(=O)CCC(C)=O)cc1>>CCCCCCCCCCCCn1c(C)ccc1-c1ccc(OC)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US06110933,CCCCCCCCCC(=O)CC(=O)OC>>CCCCCCCCCC(O)CC(=O)O,,CO,,Cl,[BH4-].[Na+],test
US05108994,CCOP(=O)(CSCCOn1cnc2c(N)ncnc21)OCC>>Nc1ncnc2c1ncn2OCCSCP(=O)(O)O,,ClCCl,,C[Si](C)(C)Br,,test
US20100099695A1,COC(=O)[C@@H](N)C1CCCCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COC(=O)[C@@H](N=C=O)C1CCCCC1,,ClCCl,,Cl,O=C([O-])O.[Na+],test
US20070032651A1,BrCCCCBr.Cc1ncc(CO)c(C2NC(C(=O)O)CC2(C(=O)O)C(=O)O)c1O.Cl.O=C([O-])[O-].[K+].[K+]>>O=C([O-])O.O=C([O-])[O-].[Br-].[Cl-].[K+].[K+],,CC(C)=O,,,,test
US20160002204A1,NCc1cccc(OC(F)(F)F)c1.O=C(O)c1cn(CC(F)CCn2ccc(COc3ccccc3)cc2=O)nn1>>O=C(NCc1cccc(OC(F)(F)F)c1)c1cn(CC(F)CCn2ccc(COc3ccccc3)cc2=O)nn1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20120245209A1,O=S(=O)(Cl)C1CC1COCc1ccccc1.O=c1[nH]c2c3occc3c(F)c(F)c2n1-c1ccc(I)cc1F>>O=c1[nH]c2c3occc3c(F)c(F)c2n1-c1ccc([IH]S(=O)(=O)C2CC2COCc2ccccc2)cc1F,CN(C)c1ccncc1,CCCCCC,ClCCl,CCOC(C)=O,,test
US20110105566A1,CN(C)c1cccc(C(=O)c2nnnn2C)c1.NO>>CN(C)c1cccc(C(=NO)c2nnnn2C)c1,,c1ccncc1,,Cl,,test
US20050054679A1,CS(=O)(=O)c1c(C(=O)O)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1.NN1CCCCC1>>CS(=O)(=O)c1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1,,CC#N,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050203078A1,CC(C)(C)OC(=O)CBr.CCOC(=O)c1ccc(NC(C)CO)c(Cl)c1>>CCOC(=O)c1ccc(NC(C)COCC(=O)OC(C)(C)C)c(Cl)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20150025065A1,CC(C)(C)OC(=O)NCC1CCN(c2ccc(Br)cc2)CC1>>NCC1CCN(c2ccc(Br)cc2)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140242099A1,Cc1cc(C)c(NC(=O)c2ccc(Br)cc2)cn1.Cc1ccc(C#N)cc1B1OC(C)(C)C(C)(C)O1>>Cc1cc(C)c(NC(=O)c2ccc(-c3cc(C#N)ccc3C)cc2)cn1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,Cc1ccccc1,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20110183960A1,NC(=O)C1(c2ccccc2)CCN(C(=O)c2cc(-c3ccc(OCCCOC4CCCCO4)cc3)c(-c3ccc(F)cc3Cl)s2)CC1>>NC(=O)C1(c2ccccc2)CCN(C(=O)c2cc(-c3ccc(OCCCO)cc3)c(-c3ccc(F)cc3Cl)s2)CC1,,CO,,Cl,,test
US06586617B1,COS(=O)(=O)OC.O=[N+]([O-])c1cc(Cl)ccc1NS(=O)(=O)/C=C/c1ccccc1>>CN(c1ccc(Cl)cc1[N+](=O)[O-])S(=O)(=O)/C=C/c1ccccc1,,CN(C)C=O,,O,[H-].[Na+],test
US20050261294A1,CC(C)(C)OC(=O)CBr.CC(C)c1ccc(-c2nccc(NCc3cccs3)n2)cc1>>CC(C)c1ccc(-c2nccc(N(CC(=O)OC(C)(C)C)Cc3cccs3)n2)cc1,,C1CCOC1,,,,test
US20040147561A1,CC(O)CNC(=O)c1cc(-c2csc(-c3ccncc3)n2)c(=O)[nH]c1C(C)C>>CC1CN=C(c2cc(-c3csc(-c4ccncc4)n3)c(=O)[nH]c2C(C)C)O1,,ClCCl,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100137194A1,CCCCCCCCNS(=O)(=O)c1ccc(OC)c(OC)c1.O=C(Cl)c1ccccc1>>CCCCCCCCN(C(=O)c1ccccc1)S(=O)(=O)c1ccc(OC)c(OC)c1,,CN(C)C=O,,[H-].[Na+],,test
US20110251173A1,COc1ccc(NC[C@@H](C)O[Si](C)(C)C(C)(C)C)cc1C#N.O=C(Cl)c1c(Cl)ncnc1Cl>>COc1ccc(N(C[C@@H](C)O[Si](C)(C)C(C)(C)C)C(=O)c2c(Cl)ncnc2Cl)cc1C#N,,C1CCOC1,,CCN(CC)CC,,test
US04297129,Cc1ccc(C(=O)O)cc1.O=c1cnn(CO)c(=O)[nH]1>>Cc1ccc(C(=O)OCn2ncc(=O)[nH]c2=O)cc1,,c1ccncc1,,,,test
US20050250810A1,CC(C)(C)OC(=O)N1CCCc2cc(/C=C/C(=O)OCc3ccccc3)cnc21>>O=C(O)/C=C/c1cnc2c(c1)CCCN2,,C1COCCO1,Cl,[Li+].[OH-],,test
US20050043331A1,CCN=C=O.COC(=O)c1[nH]cc(-c2ccc(F)cc2)c1-c1ccncc1>>CCN1C(=O)c2c(-c3ccncc3)c(-c3ccc(F)cc3)cn2C1=O,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US06194410B1,CSc1nn2c(Cl)cc(C3CC3)nc2c1S(=O)(=O)c1ccccc1.N>>CSc1nn2c(N)cc(C3CC3)nc2c1S(=O)(=O)c1ccccc1,,CO,,,,test
US09150557B1,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O.OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCl>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OCCCN1CC(O)C(O)[C@H](O)C1CO,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050038035A1,C=CCCl.O=C(Nc1ccc(N2CCNCC2)cc1)C1=C(c2ccc(C(F)(F)F)cc2)CCCC1>>C=CCN1CCN(c2ccc(NC(=O)C3=C(c4ccc(C(F)(F)F)cc4)CCCC3)cc2)CC1,,CC(C)=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20110142796A1,NCC1CC1.Nc1nccc(Cl)n1>>Nc1nccc(NCC2CC2)n1,,CCO,,,,test
US20040034090A1,C=C(C)[Mg]Br.O=[N+]([O-])c1ccccc1Br>>Cc1cc2cccc(Br)c2[nH]1,,C1CCOC1,,[Cl-].[NH4+],,test
US20050148572A1,CC(C)(C)OC(=O)N[C@@H](C(=O)O)C1Cc2ccccc2C1.COC(=O)[C@H](N)CC(C)C.O=Cc1ccc(F)cc1.[C-]#[N+]C(C)C>>CC(C)C[C@@H]1C(=O)N[C@H](C2Cc3ccccc3C2)C(=O)N1[C@@H](C(=O)NC(C)C)c1ccc(F)cc1,,CCN(CC)CC,,CO,Cl,test
US05629295,CCOCO[C@H]1CC[C@@]2(C)C(=CC[C@@H]3[C@@H]2CC[C@@]2(C)[C@H]3C[C@@H]3O[C@]4(CC[C@@H](C)CO4)[C@@H](C)[C@@H]32)C1.OO>>CCOCO[C@H]1CC[C@@]2(C)[C@H](C1)[C@@H](O)C[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1C[C@@H]1O[C@]3(CC[C@@H](C)CO3)[C@@H](C)[C@@H]12,,C1CCOC1,,CO,[Na+].[OH-],test
US20130310379A1,CC1(C)CC(N)CC(C)(C)N1.O=C(O)c1ccc(Nc2ccccc2)cc1>>CC1(C)CC(NC(=O)c2ccc(-c3ccccc3)cc2)CC(C)(C)N1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04472433,CCOC(=O)c1cccc(Oc2ccccc2Cl)c1[N+](=O)[O-]>>O=C(O)c1cccc(Oc2ccccc2Cl)c1[N+](=O)[O-],,CCO,,[K+].[OH-],,test
US04120693,N#Cc1ccc(N)c(F)c1.O=C1OC(=O)[C@H]2CCCC[C@@H]12>>N#Cc1ccc(N2C(=O)C3CCCCC3C2=O)c(F)c1,,CC(=O)O,,,,test
US06492403B1,CO.COC(=O)c1cc(C#N)c(S(C)(=O)=O)s1>>COC(=O)c1cc(C#N)c(OC)s1,,CO,,C[O-].[Na+],,test
US20120029187A1,CC1(C)CC(=O)N(Cc2ccccc2[N+](=O)[O-])CO1>>CC1(C)CC(=O)N(Cc2ccccc2N)CO1,,CCO,O,[Cl-].[NH4+],,test
US03966766,C1COCCNOCCN1.O=C(Cl)COc1ccccc1OCC(=O)Cl.c1ccccc1>>O=C1COc2ccccc2OCC(=O)N2CCOCCN1CCOCC2,,c1ccccc1,,CCN(CC)CC,,test
US20110230458A1,C=O.CCCCc1nnc(OC2CCNCC2)cc1-c1ccc(OC2CCCCC2)c(-c2nnn(C)n2)c1.Cl.Cl>>CCCCc1nnc(OC2CCN(C)CC2)cc1-c1ccc(OC2CCCCC2)c(-c2nnn(C)n2)c1.Cl.Cl,CC(=O)O,ClCCl,,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05910506,CC(=O)CCl.COc1ccc(COCc2nc(C(C)C)c(Sc3cc(Cl)cc(Cl)c3)[nH]2)cc1>>COc1ccc(COCc2nc(C(C)C)c(Sc3cc(Cl)cc(Cl)c3)n2CC(C)=O)cc1,,CC(C)=O,,[I-].[K+],,test
US20040186091A1,O=[N+]([O-])c1ccc(Cl)cc1F.OCCO>>O=[N+]([O-])c1ccc(Cl)cc1OCCO,,CN1CCCC1=O,,[H-].[Na+],,test
US20110105545A1,BrCc1ccccc1.CCOC(=O)/C=C/c1cc(O)ccc1Br>>CCOC(=O)/C=C/c1cc(OCc2ccccc2)ccc1Br,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130072677A1,CCOC(=O)c1ccc(I)cc1.COCc1ccc(B2OC(C)(C)C(C)(C)O2)cc1>>CCOC(=O)c1ccc(-c2ccc(COC)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110319411A1,COC(=O)c1c(CBr)cccc1[N+](=O)[O-].Nc1cccc(OC(F)(F)F)c1>>O=C1c2c(cccc2[N+](=O)[O-])CN1c1cccc(OC(F)(F)F)c1,,C1COCCO1,,CC(=O)O,,test
US20040229917A1,CO.Cc1cc(C#Cc2cn(-c3cncc(Cl)n3)c(C)n2)ccn1>>COc1cncc(-n2cc(C#Cc3ccnc(C)c3)nc2C)n1,,CO,,C[O-].[Na+],,test
US20060247210A1,CN1CCOCC1.Cc1n[nH]c(N)c1-c1nc2ccc(S(=O)(=O)Cl)cc2s1.NCCc1ccccc1>>Cc1n[nH]c(N)c1-c1nc2ccc(S(=O)(=O)NCCc3ccc(N)cc3)cc2s1,,CO,,,,test
US20070270420A1,CN(C)C(OC(C)(C)C)N(C)C.N#CCc1nc2ccccc2[nH]1>>CN(C)C=C(C#N)c1nc2ccccc2[nH]1,,Cc1ccccc1,,,,test
US04518602,Br.CC1CCCCOC1=O>>CC(CCCCBr)C(=O)O,,O,,O=S(=O)(O)O,,test
US20110230495A1,COC(=O)c1ncccc1C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCC(c2cccnc2CO)CC1,,C1CCOC1,CCOC(C)=O,CO,[BH4-].[Na+],test
US04853138,CCC(C)CCCCCCCCCCCCCCCCN(C)C.O=S(=O)([O-])CC(O)CCl>>CCC(C)CCCCCCCCCCCCCCCC[N+](C)(C)CC(O)CS(=O)(=O)[O-],,CC(C)O,O,[Na+].[OH-],,test
US20100216810A1,CC(=O)Nc1nc2ccc(Oc3cccc(N)c3)c(C#N)c2s1.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>CC(=O)Nc1nc2ccc(Oc3cccc(NC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)c3)c(C#N)c2s1,,CCOC(C)=O,CN(C)C=O,,,test
US20060264628A1,CI.Cc1nc2c(s1)-c1nc(Nc3cccc([N+](=O)[O-])c3)ncc1CC2>>Cc1nc2c(s1)-c1nc(N(C)c3cccc([N+](=O)[O-])c3)ncc1CC2,,CN(C)C=O,,[H-].[Na+],,test
US20060281799A1,CN(c1ncc(-c2ccc(C(F)(F)F)cc2)o1)c1cccc2c1CC(O[Si](C)(C)C(C)(C)C)CC2>>CN(c1ncc(-c2ccc(C(F)(F)F)cc2)o1)c1cccc2c1CC(O)CC2,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05221754,C=O.O=S(=O)(C=C(c1ccccc1)c1ccccc1)c1ccccc1>>O=S(=O)(C(CO)=C(c1ccccc1)c1ccccc1)c1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US20030105336A1,CN.O=C(Cl)c1ccc(-c2nn(Cc3ccccc3)c3ccccc23)o1>>CNC(=O)c1ccc(-c2nn(Cc3ccccc3)c3ccccc23)o1,,C1CCOC1,,,,test
US05153203,CN1CCC(O)CC1.O=C(O)c1cn(C2CC2)c2cc(F)c(F)cc2c1=O>>CN1CCC(Oc2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1,,CC(=O)O,,CN(C)C=O,[H-].[Na+],test
US20100009956A1,CC(C)(C)OC(=O)NNC1CCN(C(=O)OCc2ccccc2)CC1.Clc1ncc(Br)c(Cl)n1>>CC(C)(C)OC(=O)NN(c1nc(Cl)ncc1Br)C1CCN(C(=O)OCc2ccccc2)CC1,,CCO,,CCN(C(C)C)C(C)C,,test
US20070244131A1,COc1ccc(CCNc2cc(-c3cccc(S(=O)(=O)Cl)c3)nc(OC)n2)cc1.N>>COc1ccc(CCNc2cc(-c3cccc(S(N)(=O)=O)c3)nc(OC)n2)cc1,,C1COCCO1,CN(C)C=O,CCN(CC)CC,O,test
US06426417B1,CI.O=C(O)c1ccc(CCCC2OCCO2)s1>>COC(=O)c1ccc(CCCC2OCCO2)s1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100317656A1,C#C[Si](C)(C)C.CCOC(=O)c1cn2cc(I)ccc2n1>>CCOC(=O)c1cn2cc(C#C[Si](C)(C)C)ccc2n1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,,,,,test
US07629358B2,CCC1Cc2ccccc2O1.O=C1CCC(=O)N1Br>>CCC1Cc2cc(Br)ccc2O1,,ClCCl,,,,test
US20040248875A1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.N#Cc1cnn2c1NCCC2>>N#Cc1cnn2c1N(C(c1ccccc1)(c1ccccc1)c1ccccc1)CCC2,,c1ccncc1,,,,test
US20090247517A1,COC(=O)c1ccc(C(=O)C=CN(C)C)cc1.N=C(N)N>>O=C(O)c1ccc(-c2ccnc(O)n2)cc1,,CO,,Cl,[Na+].[OH-],test
US20130324528A1,CNC(=O)CBr.Cc1ccc(F)c(-c2cc(Nc3ccnc4cn[nH]c34)ccn2)n1>>CNC(=O)Cn1cc2nccc(Nc3ccnc(-c4nc(C)ccc4F)c3)c2n1,,CN(C)C=O,,[H-].[Na+],,test
US20080269335A1,CCOC(=O)COc1ccc(C(F)(F)F)cc1C1C=CCCC1>>O=C(O)COc1ccc(C(F)(F)F)cc1C1C=CCCC1,,C1COCCO1,O,Cl,[Na+].[OH-],test
US20060178418A1,CCOc1ccc(C(=O)Oc2ccc([N+](=O)[O-])cc2)c2c3cc(Cl)ccc3n(Cc3ccccc3)c12.Nc1c(Cl)cncc1Cl>>CCOc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2c3cc(Cl)ccc3n(Cc3ccccc3)c12,,CN(C)C=O,,Cl,[H-].[Na+],test
US20140024650A1,CC(=O)OC[C@H]1OCC=C[C@H]1OC(C)=O>>OC[C@H]1OCC=C[C@H]1O,,CO,,[Cl-].[NH4+],,test
US20130123235A1,COC(=O)c1c(NC(=O)C(C)(C)C)cccc1OCCC(=O)O>>COC(=O)c1c(NC(=O)C(C)(C)C)ccc2c1OCCC2=O,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US06265426B1,N#Cc1cccc(-c2cnc(-c3ccc(Cl)c(Cl)c3)[nH]2)c1>>NCc1cccc(-c2cnc(-c3ccc(Cl)c(Cl)c3)[nH]2)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20050261291A1,CCC1(CC)CC=C(c2ccc(OC)cc2N2CCNCC2)CC1.O=CC1CCOCC1>>CCC1(CC)CC=C(c2ccc(OC)cc2N2CCN(CC3CCOCC3)CC2)CC1,,C1CCOC1,,CC(=O)O,O=C([O-])O.[Na+],test
US20160002204A1,CCOC(=O)c1cn(CC(F)CCn2ccc(NC(=O)Cc3ccccc3)cc2=O)nn1>>O=C(Cc1ccccc1)Nc1ccn(CCC(F)Cn2cc(C(=O)O)nn2)c(=O)c1,,C1CCOC1,CO,[Li+].[OH-],,test
US04997667,CCOC(=O)CCNC(=S)Nc1ccc2cn[nH]c2c1>>O=C(O)CCNC(=S)Nc1ccc2cn[nH]c2c1,,CO,O,[Na+].[OH-],,test
US20080269196A1,N#Cc1ccc(C(=O)CSCC(F)(F)F)cc1.OCCO>>N#Cc1ccc(C2(CSCC(F)(F)F)OCCO2)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120214803A1,Nc1cccc2c(Cl)ccnc12.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>O=[N+]([O-])c1ccccc1S(=O)(=O)Nc1cccc2c(Cl)ccnc12,CN(C)c1ccncc1,ClCCl,,c1ccncc1,,test
US20060116364A1,COc1ccc2c(c1)CC=C(c1ccc(OC)cc1[N+](=O)[O-])C2(C)C>>COc1ccc(C2CCc3cc(OC)ccc3C2(C)C)c(N)c1,[Pd],C1CCOC1,CO,,,test
US20030186992A1,CC(C)(C)OC(=O)N1CCC(O)(C(C(=O)N2CCN(CCCCc3cccc4ccccc34)CC2)c2ccc(F)cc2)CC1>>CN1CCC(O)(C(C(=O)N2CCN(CCCCc3cccc4ccccc34)CC2)c2ccc(F)cc2)CC1,,CO,,C1COCCO1,Cl,test
US08609849B1,CC(C)NC(C)C.O=Cc1ccccc1F>>CC(C)(C#N)C(O)c1ccccc1F,,C1CCOC1,,O,[Li]CCCC,test
US09096592B2,Nc1cnc(-c2nn(Cc3ccccc3F)c3ncccc23)nc1N.O=C1CCN(C2CC2)CC1>>Nc1nc(-c2nn(Cc3ccccc3F)c3ncccc23)ncc1NC1CCN(C2CC2)CC1,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US04032559,C1CCNCC1.CCOC(CC#N)=NC#N>>N#CCC(=NC#N)N1CCCCC1,,CO,,,,test
US06207693B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)CCCCCOc1cc(C)ccc1N(C)C(=O)c1ccc(NC(=O)c2cccc3[nH]c(CN)nc23)c(OC)c1>>CCOC(=O)CCCCCOc1cc(C)ccc1N(C)C(=O)c1ccc(NC(=O)c2cccc3[nH]c(CNC(=O)OC(C)(C)C)nc23)c(OC)c1,,ClCCl,,CCN(CC)CC,,test
US05424443,CCOC(=O)C1CCCCN1.O=C=Nc1c(F)cc(Cl)c2nc(Cl)sc12>>O=C1C2CCCCN2C(=O)N1c1c(F)cc(Cl)c2nc(Cl)sc12,,C1CCOC1,,,,test
US20100249176A1,OCc1ccc2cn[nH]c2c1>>O=Cc1ccc2cn[nH]c2c1,O=[Mn]=O,ClCCl,,,,test
US20080176871A1,Cc1cc(C)c(Oc2nc(Cl)nc3ccsc23)c(C)c1.N#Cc1ccc(N)cc1>>Cc1cc(C)c(Oc2nc(Nc3ccc(C#N)cc3)nc3ccsc23)c(C)c1,,CCOC(C)=O,,O=C(O)C(F)(F)F,,test
US20100311966A1,COC1(OC)CCN(C(=O)OC(C)(C)C)CC1O.Cc1ccc(S(=O)(=O)OCC(F)F)cc1>>COC1(OC)CCN(C(=O)OC(C)(C)C)CC1OCC(F)F,,CN(C)C=O,,[H-].[Na+],,test
US05747537,O=C(O)CCCCCCC=Cc1cccs1>>O=C(O)CCCCCCCCc1cccs1,[Pd],,,,,test
US05034393,NC=O.Nc1cccnc1C(=O)O>>O=c1[nH]cnc2cccnc12,,O,,,,test
US20040106653A1,COC(=O)Cc1cc(S(=O)(=O)c2ccc(CCNC(=O)C(F)(F)F)cc2)ccc1OC>>COC(=O)Cc1cc(S(=O)(=O)c2ccc(CCNC(=O)C(F)(F)F)cc2)ccc1O,,ClCCl,,BrB(Br)Br,,test
US06627629B2,CC(C)(C)OC(=O)N[C@@H]1CCCO[C@@H]1C=Cc1ccccc1.O=[O+][O-]>>CC(C)(C)OC(=O)N[C@@H]1CCCO[C@H]1C=O,,CO,,,,test
US20140296526A1,O=C1CC[C@@H](C(=O)O)N1.[NH4+]>>NC(=O)[C@@H]1CCC(=O)N1,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20080056990A1,CS(=O)(=O)OCCOCCOc1cc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2cc1[N+](=O)[O-].O=[N+]([O-])c1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OCCOCCOCCOCCOCCOCCO>>CS(=O)(=O)OCCOCCOCCOCCOCCOCCOc1cc2ncnc(Nc3cc(Cl)c(Cl)cc3F)c2cc1[N+](=O)[O-],,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20140114068A1,Cc1cc2c(cc1C)C1(NC(=O)c3cccnc3)C(=O)c3c([N+](=O)[O-])cccc3C1(O)O2>>Cc1cc2c(cc1C)C1(NC(=O)c3cccnc3)C(=O)c3c(N)cccc3C1(O)O2,[Fe],CCO,,Cl,O,test
US20040116438A1,COC(=O)c1cnccc1NC(=O)C(NC(=O)OCc1ccccc1)C(C)C>>CC(C)C(NC(=O)OCc1ccccc1)C(=O)Nc1ccncc1C(=O)O,,O,,CO,[Na+].[OH-],test
US20140315917A1,CC(=O)Nc1cc(C)c(Oc2ccnc(-c3cnn(C)c3)c2)c(C)n1>>Cc1cc(N)nc(C)c1Oc1ccnc(-c2cnn(C)c2)c1,,C1CCOC1,,Cl,,test
US20110105461A1,CC(C)N.Cc1ccc(S(=O)(=O)OCC2COc3ccc(S(C)(=O)=O)cc3O2)cc1>>CC(C)NCC1COc2ccc(S(C)(=O)=O)cc2O1,,CC#N,,,,test
US20110118236A1,C1CCNC1.O=C(Cl)c1ccc(CBr)cc1>>O=C(c1ccc(CBr)cc1)N1CCCC1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,Cl,test
US20120214769A1,COC(=O)c1ccc(C(=O)C2C(=O)OC(C)(C)OC2=O)cc1>>COC(=O)c1ccc(CC2C(=O)OC(C)(C)OC2=O)cc1,,CCOCC,ClCCl,CC(=O)O,[BH4-].[Na+],test
US08618162B2,BrCC1CCCCC1.Oc1ccccc1O>>Oc1ccccc1OCC1CCCCC1,,Cl,,CO,C[O-].[Na+],test
US20120071461A1,CN(CCC1CCN(C(=O)OC(C)(C)C)CC1)Cc1ccccc1>>CN(CCC1CCNCC1)Cc1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160222033A1,CCN(Cc1cc(=O)n2c(CC=O)c(C)sc2n1)c1ccc(F)cc1>>CCN(Cc1cc(=O)n2c(CCO)c(C)sc2n1)c1ccc(F)cc1,,CO,,[BH4-].[Na+],,test
US20120015942A1,COC(=O)C1CCc2cc(F)c(OC)cc2C1>>COc1cc2c(cc1F)CCC(C(=O)O)C2,,CO,,[Na+].[OH-],,test
US05155268,CS(=O)(=O)Nc1ccc(CCC(=O)OCc2ccccc2)cc1>>CS(=O)(=O)Nc1ccc(CCC(=O)O)cc1,[Pd],CCO,,,,test
US04328355,C#C[Si](CC)(CC)CC.CC(=O)CCc1ccccc1>>C#CC(C)(O)CCc1ccccc1,,CCOCC,CCOCC,Cl,[Li]CCCC,test
US20110268653A1,CCCCCC(=O)Cl.CCCCCC=O.NC(=O)C[C@H](N)C(=O)O>>CCCCCC(=O)N1C(CCCCC)NC(=O)CC1C(=O)O,,CO,,,,test
US20150291597A1,C#CCNc1nc(Cl)nc(Cl)n1.NC1CC1>>C#CCNc1nc(Cl)nc(NC2CC2)n1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20140094489A1,CC(C)CNCc1ccc(C(=O)OC(C)(C)C)s1.COC(=O)C[C@H](NC(=O)Oc1ccccc1)C(=O)OC>>COC(=O)C[C@H](NC(=O)N(Cc1ccc(C(=O)OC(C)(C)C)s1)CC(C)C)C(=O)OC,,CC#N,,CCN(C(C)C)C(C)C,,test
US20160152561A1,COc1cc(F)ccc1O.NS(=O)(=O)c1cccc(NC(=O)c2c(F)cc(C(F)(F)F)cc2C(F)(F)F)c1>>COc1cc(F)ccc1Oc1cc(C(F)(F)F)cc(C(F)(F)F)c1C(=O)Nc1cccc(S(N)(=O)=O)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150073011A1,C=CCON1C(=O)N2C[C@H]1C=C(C)[C@H]2CO[Si](C)(C)C(C)(C)C>>C=CCON1C(=O)N2C[C@H]1C=C(C)[C@H]2CO,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150191450A1,CCN1CCN(Cc2ccc([N+](=O)[O-])cc2C(F)(F)F)CC1>>CCN1CCN(Cc2ccc(N)cc2C(F)(F)F)CC1,[Pd],CO,,,,test
US04818761,Fc1cccc(-n2c(CCl)nc3ccccc32)c1.Nc1ccncc1>>Fc1cccc(-n2c(CNc3ccncc3)nc3ccccc32)c1,,CCO,,,,test
US20040006141A1,CCOC(=O)C(C)(CCCc1ccccc1)Cc1ccc(OCc2ccccc2)cc1>>CCOC(=O)C(C)(CCCc1ccccc1)Cc1ccc(O)cc1,[Pd],,,,,test
US20070293494A1,CS(=O)(=O)N1CCN(CCCN)CC1.Clc1cccc(Nc2nccc(Cl)n2)c1>>CS(=O)(=O)N1CCN(CCCNc2ccnc(Nc3cccc(Cl)c3)n2)CC1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20150031679A1,COc1ccc(/C=N/C(C)CO)cc1>>COc1ccc(CNC(C)CO)cc1,,CO,,[BH4-].[Na+],,test
US20060020133A1,CCI.COC1(OC)CCOCC1O>>CCOC1COCCC1(OC)OC,,C1CCOC1,,[H-].[Na+],,test
US05998623,COc1ccc(Cn2ncnc2CN2CCc3cc([N+](=O)[O-])ccc3C2)cc1>>COc1ccc(Cn2ncnc2CN2CCc3cc(N)ccc3C2)cc1,[Pd],CO,,,,test
US20140073700A1,COC(=O)[C@@]1(C)CC[C@]2(C)CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)C(=O)C(I)=C[C@]5(C)C4=CC(=O)[C@]3(O)[C@@H]2C1.N#C[Cu]>>COC(=O)[C@@]1(C)CC[C@]2(C)CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)C(=O)C(C#N)=C[C@]5(C)C4=CC(=O)[C@]3(O)[C@@H]2C1,,CN1CCCC1=O,,,,test
US05175301,CN.Fc1ccc(CBr)cn1>>CNCc1ccc(F)nc1,,CC#N,,,,test
US20080167287A1,CC(C)(C)OC(=O)Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1.Fc1cc(Br)ccc1I>>CC(C)(C)OC(=O)Cn1cc(-c2ccc(Br)cc2F)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,O,O=C([O-])[O-].[Na+].[Na+],,test
US04006017,CCn1c2ccccc2c2ccccc21.N#CC(C#N)=C(C#N)C#N>>CCn1c2ccccc2c2cc(C(C#N)=C(C#N)C#N)ccc21,,O,,CN(C)C=O,,test
US05849764,Cc1cc(C)cc(B(O)O)c1.O=C1c2ccccc2C(=O)N1CCc1c(Br)[nH]c2ccccc12>>Cc1cc(C)cc(-c2[nH]c3ccccc3c2CCN2C(=O)c3ccccc3C2=O)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,Cc1ccccc1,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US20020004518A1,CC(=O)O.Cc1ccc(C(=O)c2ccccc2)cc1.O=S(=O)(O)O>>O=C(O)c1ccc(C(=O)c2ccccc2)cc1,,O,,,,test
US06358971B1,CSSC.O=C(c1ccccc1)c1ccc2nc(NC(=O)C(F)(F)F)c(I)n2c1>>CSc1c(NC(=O)C(F)(F)F)nc2ccc(C(=O)c3ccccc3)cn12,[Cu],c1ccncc1,,O,[K+].[OH-],test
US20130023514A1,COc1ccc(CN(C(=O)C(C)(C)COC(=O)N2CCOCC2)[C@@H]2CC[C@@H](NC(=O)OC(C)(C)C)CC2)cc1>>CC(C)(COC(=O)N1CCOCC1)C(=O)N[C@@H]1CC[C@@H](N)CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100022513A1,CCOC(=O)c1sc(NC(=O)C(C)(C)N)nc1-c1ccccc1.O=C(Cl)c1ccc(F)cc1>>CCOC(=O)c1sc(NC(=O)C(C)(C)NC(=O)c2ccc(F)cc2)nc1-c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US20100190747A1,COC(=O)C(C)CCSc1nc2cc[nH]c2c(=O)n1-c1ccc(OCC(F)(F)F)cc1>>CC(CCSc1nc2cc[nH]c2c(=O)n1-c1ccc(OCC(F)(F)F)cc1)C(=O)O,,CO,,C1CCOC1,[Na+].[OH-],test
US05472964,COC(=O)c1ccc2scc(Br)c2n1>>OCc1ccc2scc(Br)c2n1,,C1CCOC1,,CC(C)C[AlH]CC(C)C,,test
US20080090794A1,CC(C)(C)[S@](=O)N=Cc1cccc(C#N)c1.c1cncc(Cc2cccnc2)c1>>CC(C)(C)S(=O)NC(c1cccc(C#N)c1)C(c1cccnc1)c1cccnc1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US05986094,C[C@@H](Cc1ccccc1)NC(=O)C(F)(F)F.O=S(=O)(O)Cl>>C[C@@H](Cc1ccc(S(=O)(=O)Cl)cc1)NC(=O)C(F)(F)F,,ClC(Cl)Cl,,,,test
US20060035912A1,Cc1cc(C(=O)c2cn(C(C)C)c3ncnc(N)c23)cc(N)n1.O=C=Nc1ccccc1F>>Cc1cc(C(=O)c2cn(C(C)C)c3ncnc(N)c23)cc(NC(=O)Nc2ccccc2F)n1,,c1ccncc1,,,,test
US05700809,C(=Cc1ccco1)c1ccncc1>>c1cc(CCC2CCCO2)ccn1,[Pd],CO,,O=C[O-].[NH4+],,test
US06713473B1,COC(=O)CCCCCNS(=O)(=O)c1cccc2ccccc12>>O=C(O)CCCCCNS(=O)(=O)c1cccc2ccccc12,,CO,,[Na+].[OH-],,test
US20160052913A1,CC[N+]1(C)CCC(=O)CC1.NCC1CCCCCC1>>O=C1CCN(CC2CCCCCC2)CC1,,CCO,O,[I-].[K+],,test
US20110230458A1,CCCCc1nnc(C(=O)NCC2CNCCO2)cc1-c1ccc(OC2CCCCC2)cc1.CN1C2CCC1CC(N)C2.Cl.Cl>>CCCCc1nnc(C(=O)NC2CC3CCC(C2)N3C)cc1-c1ccc(OC2CCCCC2)cc1.Cl.Cl,,C1CCOC1,CCOCC,CCN(C(C)C)C(C)C,,test
US20050101063A1,C#C[Si](C)(C)C.O=[N+]([O-])c1cc(Br)ccc1Br>>C[Si](C)(C)C#Cc1ccc(Br)cc1[N+](=O)[O-],[Cu]I,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20130267510A1,C[C@@H](N)C(=O)Nc1ccc(Oc2cccc3c2COC3)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>C[C@H]1NC(=O)N(c2ccc(Oc3cccc4c3COC4)cc2)C1=O,,ClCCl,,O=C([O-])O.[Na+],,test
US20070244155A1,COC(=O)CC1COCc2cc(OCc3cccc(-c4ccc(C(F)(F)F)cc4)c3)ccc21>>O=C(O)CC1COCc2cc(OCc3cccc(-c4ccc(C(F)(F)F)cc4)c3)ccc21,,CCO,O,[Na+].[OH-],,test
US20110207698A1,CN.N#Cc1c(Cl)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1cc[nH]n1>>CNc1nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c(-c2cc[nH]n2)c1C#N,,C1CCOC1,,CO,,test
US04186135,CCN1CCCC1CN.CCS(=O)(=O)c1cc2c(c(C(=O)O)c1)OCCO2>>CCN1CCCC1CNC(=O)c1cc(S(=O)(=O)CC)cc2c1OCCO2,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20100143341A1,CC(C)(C)OC(=O)N1CCC(O)C1.O=[N+]([O-])c1ccccc1F>>CC(C)(C)OC(=O)N1CCC(Oc2ccccc2[N+](=O)[O-])C1,,C1CCOC1,C1CCOC1,O,[H-].[Na+],test
US20090286811A1,CCCCCOc1c(C=O)cccc1OC.Cc1nc2sccn2c(=O)c1-c1ccc(OC(F)(F)F)cc1>>CCCCCOc1c(/C=C/c2nc3sccn3c(=O)c2-c2ccc(OC(F)(F)F)cc2)cccc1OC,,CCO,,C,C[O-].[Na+],test
US20100130468A1,C1CCNC1.O=Cc1ccc(Br)s1>>Brc1ccc(CN2CCCC2)s1,CC(=O)O,CN(C)C=O,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04006144,O=C1Cc2cc(Cl)ccc2Sc2ccccc21.O=C1OCCN1CCN1CCNCC1>>O=C1OCCN1CCN1CCN(C2=Cc3cc(Cl)ccc3Sc3ccccc32)CC1,Cl[Ti](Cl)(Cl)Cl,c1ccccc1,,O=C([O-])O.[Na+],,test
US20160021883A1,[N-]=[N+]=NCc1ccc(-c2ncn(-c3ccc(OC(F)(F)C(F)(F)F)cc3)n2)cc1>>NCc1ccc(-c2ncn(-c3ccc(OC(F)(F)C(F)(F)F)cc3)n2)cc1,[Pd],CCOC(C)=O,,,,test
US20070155744A1,COCOc1cccnc1Cl.OCc1ccccc1>>COCOc1cccnc1OCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US05523486,C=C1CC(=O)O1.Cc1ccc(N)c(C)c1>>CC(=O)CC(=O)Nc1ccc(C)cc1C,,O,,CCO,,test
US20140147529A1,CCCCCC(=O)Cl.O=[N+]([O-])OCCCO>>CCCCCC(=O)OCCCO[N+](=O)[O-],,CCOCC,,CCN(CC)CC,,test
US20160024103A1,CCOC(=O)c1c(-c2ccc(F)cc2)oc2cc(Br)c(OC(C)C)cc12>>CC(C)Oc1cc2c(C(=O)O)c(-c3ccc(F)cc3)oc2cc1Br,,C1CCOC1,,CO,[Na+].[OH-],test
US20120149681A1,CCOC(=O)c1cc(Cl)nc(C(F)(F)F)c1>>OCc1cc(Cl)nc(C(F)(F)F)c1,,CCO,,[BH4-].[Na+],,test
US20160257668A1,C1COCCN1.C[Si](C)(C)CCOCn1ncc2cc(NC(=O)c3ncc(F)cc3-c3ccc(F)cc3)ccc21>>C[Si](C)(C)CCOCn1ncc2cc(NC(=O)c3ncc(N4CCOCC4)cc3-c3ccc(F)cc3)ccc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040014962A1,CC(C)(C)[Si](C)(C)Cl.CC(C)C[C@@H](CO)NC(=O)c1csc(N2CC(O)C2)n1>>CC(C)C[C@@H](CO[Si](C)(C)C(C)(C)C)NC(=O)c1csc(N2CC(O)C2)n1,,CN(C)C=O,,c1c[nH]cn1,,test
US20130267571A1,C1CCOC1.CC(C)OC(=O)N=NC(=O)OC(C)C.O=C1NC(=O)c2ccccc21.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CC(C)=CCC/C(C)=C/C(c1ccccc1)N1C(=O)c2ccccc2C1=O,,C1CCOC1,,,,test
US20070265225A1,CCC(Cl)C(=O)Cl.N[C@@H](CO)c1cc(F)cc(F)c1>>CCC(Cl)C(=O)N[C@@H](CO)c1cc(F)cc(F)c1,,ClCCl,,CCN(CC)CC,,test
US20110070317A1,CC(C)(C)OC(=O)N[C@@H]1CCCNC1.O=C(Nc1c[nH]c2ncc(Br)c(F)c12)C1CCCO1>>CC(C)(C)OC(=O)N[C@@H]1CCCN(c2c(Br)cnc3[nH]cc(NC(=O)C4CCCO4)c23)C1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20100093814A1,COc1ccc(Cl)cc1C(=O)Nc1ncc(C)s1.ClCc1ccco1>>COc1ccc(Cl)cc1C(=O)/N=c1\sc(C)cn1Cc1ccco1,,CN(C)C=O,,[H-].[Na+],,test
US20160016903A1,Cc1ccc(C2(N(C)C)CCC3(CC2)CC(=O)N(C(=O)OC(C)(C)C)C3)s1>>Cc1ccc(C2(N(C)C)CCC3(CC2)CNC(=O)C3)s1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070093521A1,CCOc1cc(C=O)cc(OCC)c1F.COC(=O)COc1ccc2oc(NC3CCNCC3)nc2c1>>CCOc1cc(CN2CCC(Nc3nc4cc(OCC(=O)OC)ccc4o3)CC2)cc(OCC)c1F,,CC(=O)O,CCO,CCN(C(C)C)C(C)C,[BH3-]C#N.[Na+],test
US20090186917A1,COC(=O)[C@H](NC(=O)OC(C)(C)C)c1ccccc1.CSC>>COC(=O)[C@@H](c1ccccc1)N(C)C(=O)OC(C)(C)C,,CN(C)C=O,,[H-].[Na+],,test
US20080021087A1,CC(C)(C)[Mg]Cl.CCOC(=O)C(=O)Nc1c(C)c(C)c2c(c1C)C(c1ccc(C(C)C)cc1)CO2>>Cc1c(C)c2c(c(C)c1NC(=O)C(=O)C(C)(C)C)C(c1ccc(C(C)C)cc1)CO2,,C1CCOC1,,,,test
US05723452,Cc1cc(C)cc(Sc2cccc(F)c2C#N)c1.O=S([O-])OO>>Cc1cc(C)cc(S(=O)(=O)c2cccc(F)c2C#N)c1,,CO,,O,,test
US20150266825A1,C1=COCCC1.O=C(O)c1n[nH]c2cc(F)c(Br)cc12>>O=C(O)c1nn(C2CCCCO2)c2cc(F)c(Br)cc12,O=C(O)C(F)(F)F,CC#N,,,,test
US20150361100A1,Nc1ncnc2nc[nH]c12.OCc1cn2ccccc2c1-c1ccccc1>>Nc1ncnc2c1ncn2Cc1cn2ccccc2c1-c1ccccc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070124152A1,CCOC(=O)CC(=O)N(c1cc(Cc2ccc(F)cc2)cnc1C(=O)OC)C1CC1>>CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(C2CC2)c1=O,,CCO,,C,C[O-].[Na+],test
US06252082B1,COC(=O)Cn1c(C)cc(OS(=O)(=O)C(F)(F)F)c([N+](=O)[O-])c1=O.Oc1ccccc1>>COC(=O)Cn1c(C)cc(Oc2ccccc2)c([N+](=O)[O-])c1=O,,C1CCOC1,,Cl,[H-].[Na+],test
US20160108035A1,N#C/C=C/c1ccc2nccc(O)c2c1>>N#CCCc1ccc2nccc(O)c2c1,[Pd],CO,ClCCl,CCN(CC)CC,,test
US05210022,CC(=O)Oc1cn(C(C)=O)c2cc(Cl)ccc12>>CC(=O)n1cc(O)c2ccc(Cl)cc21,,O,,O=S(=O)(O)O,,test
US07427683B2,CC1CCN(c2cc(Br)ccc2[N+](=O)[O-])CC1>>CC1CCN(c2cc(Br)ccc2N)CC1,[Fe],O,,CCO,[Cl-].[NH4+],test
US20090275590A1,Cl.Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CCN(CCN1CCCC1)C2>>Cl.Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CCN(CCN1CCCC1)C2,,ClCCl,,CCOCC,,test
US20050054851A1,CC(C)(C)OC(=O)N1CCN(c2ccc(OCCOC3CCCCO3)cc2F)CC1>>OCCOc1ccc(N2CCNCC2)c(F)c1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US06492421B1,CC(Cl)CN1CCCCC1.COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(C)cc1>>Cc1ccc(S(=O)(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2ccc(OCCCN3CCCCC3)cc2)C(=O)O)cc1,,CCC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US04137318,COc1cc2c(cc1OC)C(=O)NCC2.ClCCCBr>>COc1cc2c(cc1OC)C(=O)N(CCCCl)CC2,,CN(C)C=O,,[H-].[Na+],,test
US20070049616A1,Brc1ccccc1C1CCCc2cncn21.OB(O)c1cccs1>>c1csc(-c2ccccc2C2CCCc3cncn32)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20080214615A1,CNCc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O.O=C=Nc1ccc2ccccc2c1>>CN(Cc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O)C(=O)Nc1ccc2ccccc2c1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20070185103A1,O=C(OCc1ccccc1)C1CCCNC1.O=C1CCCC1>>O=C(OCc1ccccc1)C1CCCN(C2CCCC2)C1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130029962A1,CC#N.CC(=O)OCC(F)(F)F>>N#CCC(=O)C(F)(F)F,,C1COCCO1,,[H-].[Na+],,test
US20110039842A1,O=c1c(OCc2ccccc2)c(-c2noc(Cc3ccc(F)cc3)n2)nc2ccc(N3CCOCC3)cn12>>O=c1c(O)c(-c2noc(Cc3ccc(F)cc3)n2)nc2ccc(N3CCOCC3)cn12,,ClCCl,,Cl,,test
US20160145251A1,CC(C)(C)OC(=O)N1CC(N=[N+]=[N-])CC(C(=O)Nc2ccc(Cl)cc2)C1>>[N-]=[N+]=NC1CNCC(C(=O)Nc2ccc(Cl)cc2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100244012A1,Cc1ccc(C2(O)c3ccccc3C(O)(c3ccc(C)c4ccccc34)c3cc(-c4ccc5ccc([Si](C(C)C)(C(C)C)C(C)C)cc5c4)ccc32)c2ccccc12>>Cc1ccc(-c2c3ccccc3c(-c3ccc(C)c4ccccc34)c3cc(-c4ccc5ccc([Si](C(C)C)(C(C)C)C(C)C)cc5c4)ccc23)c2ccccc12,,CC(=O)O,,,,test
US20090215743A1,CCOC(=O)C1CCCCN1C(=O)CC1OC(c2cccc(OC)c2OC)c2cc(Cl)ccc2-n2c(C(C)C)nnc21>>COc1cccc(C2OC(CC(=O)N3CCCCC3C(=O)O)c3nnc(C(C)C)n3-c3ccc(Cl)cc32)c1OC,,C1COCCO1,,Cl,,test
US20040009995A1,NO.O=Cc1cc(Br)c([N+](=O)[O-])s1>>O=[N+]([O-])c1sc(C=NO)cc1Br,,CCO,,Cl,c1ccncc1,test
US20060217380A1,CC[O-].COc1ccc(CC(=O)[O-])cc1[N+](=O)[O-]>>COc1ccc(O)cc1[N+](=O)[O-],,CCO,,Cl,,test
US20120258950A1,CC(C)n1ncc(CO)c1C(F)(F)F.O=S(Cl)Cl>>CC(C)n1ncc(CCl)c1C(F)(F)F,,ClCCl,,,,test
US20060030613A1,CC(C)(C)c1ccc(C=O)cc1.Cc1ccc(CCN)cc1>>Cc1ccc(CCNCc2ccc(C(C)(C)C)cc2)cc1,Cl,CO,,[BH4-].[Na+],,test
US20040127574A1,Brc1cccnc1.O=C(OCc1ccccc1)c1ccc(O)cc1>>O=C(OCc1ccccc1)c1ccc(Oc2cccnc2)cc1,[Cu],CN(C)C=O,,CC(C)(C)[O-].[K+],,test
US05304549,CC(=O)OC(C)=O.CC(C)C[C@@H](C(=O)OCc1ccccc1)C(CCCO)(C(=O)OCc1ccccc1)C(=O)OC(C)(C)C>>CC(=O)OCCCC(C(=O)OCc1ccccc1)(C(=O)OC(C)(C)C)[C@@H](CC(C)C)C(=O)OCc1ccccc1,,c1ccncc1,,,,test
US20080261944A1,CC(C)(C)OC(=O)c1ccc2c(C3CCCCC3)c(-c3ccccc3)[nH]c2c1.CN(C)C(=O)CCl>>CN(C)C(=O)Cn1c(-c2ccccc2)c(C2CCCCC2)c2ccc(C(=O)O)cc21,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US04758587,COc1cc(OC)c2ccccc2c1O.O=C(Cl)Cl>>COc1cc(OC)c2ccccc2c1OC(=O)Cl,,C1CCOC1,c1ccccc1,c1ccncc1,,test
US20070124152A1,CCOC(=O)CC(=O)N(CCN1CCCC1=O)c1cc(Cc2ccc(F)cc2)cnc1C(=O)OCC>>CCOC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN2CCCC2=O)c1=O,,CCO,,C1CCC2=NCCCN2CC1,,test
US04638067,CCn1cc(C(=O)O)c(=O)c2cc(F)c(Cl)nc21.NCC1CCNCC1>>CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCC(CN)CC3)nc21,,CC#N,,,,test
US20100136136A1,Cc1cc(OCC2CCN(C(=O)OC(C)(C)C)CC2)ccc1[N+](=O)[O-]>>Cc1cc(OCC2CCN(C(=O)OC(C)(C)C)CC2)ccc1N,[Pd],CCOC(C)=O,CO,[H][H],,test
US20050049259A1,CCCCN.Fc1ccc(-c2nn3c(Cl)cccc3c2-c2ccncc2)cc1>>CCCCNc1cccc2c(-c3ccncc3)c(-c3ccc(F)cc3)nn12,,Cc1ccccc1,,,,test
US20090233879A1,CC(=O)OC1(C)[C@@H](COC(=O)c2ccccc2)OC(n2cnc3c(Cl)ncnc32)[C@]1(C)F.NCc1ccccc1Cl>>CC(=O)OC1(C)[C@@H](COC(=O)c2ccccc2)OC(n2cnc3c(NCc4ccccc4Cl)ncnc32)[C@]1(C)F,,CCO,,O,,test
US20120309673A1,CC(C)(C)OC(=O)NC1(C(O)C(=O)O)CCC1.Cn1ccc(N)n1>>Cn1ccc(NC(=O)C(O)C2(NC(=O)OC(C)(C)C)CCC2)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040162279A1,C[C@H]1CN(c2ccc([N+](=O)[O-])cc2C=O)C[C@H](C)O1.O=C1CC(=O)NC(=O)N1>>C[C@H]1CN2c3ccc([N+](=O)[O-])cc3CC3(C(=O)NC(=O)NC3=O)[C@H]2[C@H](C)O1,,CO,,,,test
US20100311732A1,CC(C)(C)OC(=O)NC(CC(=O)N1CC(=O)N(CC(=O)NC2CC2)c2ccccc2C1)Cc1cc(F)c(F)cc1F.O=C(O)C(F)(F)F>>N[C@@H](CC(=O)N1CC(=O)N(CC(=O)NC2CC2)c2ccccc2C1)Cc1cc(F)c(F)cc1F.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20060089404A1,BrCCCOCc1ccccc1.CCC(C)(Oc1ccc(O)cc1)C(=O)OC>>CCC(C)(Oc1ccc(OCCCO)cc1)C(=O)OC,[Pd],CN(C)C=O,CO,O,O=C([O-])[O-].[Cs+].[Cs+],test
US06057369,COc1ccc(S(=O)(=O)[C@H](CCCCc2ccccc2)[C@H](CO)C(=O)OC(C)(C)C)cc1>>COc1ccc(S(=O)(=O)C(CCCCc2ccccc2)C(CO)C(=O)O)cc1,,ClCCl,,CO,O=C(O)C(F)(F)F,test
US05198208,COC(=O)[C@H](COCc1ccccc1)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@H](C=O)COCc1ccccc1,,Cc1ccccc1,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US05155113,CCCOc1ccc(C(=O)Cl)cc1.O=c1cc(O)cc[nH]1>>CCCOc1ccc(C(=O)Oc2cc[nH]c(=O)c2)cc1,,c1ccncc1,,,,test
US20030166639A1,CCOc1cc(NC(=O)OC(C)(C)C)c(NC(=O)CC(=O)c2cccc(-c3cc(C)nc(C4CC4)c3)c2)cc1C(F)(F)F>>CCOc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3cc(C)nc(C4CC4)c3)c1)=N2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120295897A1,O=C1N(C(c2ccccc2)c2ccccc2)c2cccc(Br)c2C12COc1cc3c(cc12)OCCO3.OB(O)c1cnc2ccccc2c1>>O=C1N(C(c2ccccc2)c2ccccc2)c2cccc(-c3cnc4ccccc4c3)c2C12COc1cc3c(cc12)OCCO3,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20130085142A1,Clc1ccc(O[C@@H]2C[C@H]3CNCCN3C2)nc1.FC(F)(F)c1cccc(Cl)n1>>FC(F)(F)c1cccc(N2CCN3C[C@H](Oc4ccc(Cl)cn4)C[C@H]3C2)n1,,CS(C)=O,,O=C([O-])[O-].[Na+].[Na+],,test
US04707488,[N-]=[N+]=NCCCc1cc(Cl)cc(Cl)c1>>NCCCc1cc(Cl)cc(Cl)c1,[Ni],,,,,test
US20130303538A1,CI.COC(=O)N1CC[C@H]2[C@@H]1CCC[C@]2(O)C#Cc1cccc(C)c1>>COC(=O)N1CC[C@@H]2[C@H]1CCC[C@]2(C#Cc1cccc(C)c1)OC,O=[Ag-],CN(C)C=O,,CCOC(C)=O,,test
US20100240656A1,CCCCn1c(Sc2ccc3c(c2)OCO3)nc2c(=O)[nH]cnc21.O=[N+]([O-])c1ccc(Cl)c([N+](=O)[O-])c1>>CCCCn1c(Sc2ccc3c(c2)OCO3)nc2c(=O)n(-c3ccc([N+](=O)[O-])cc3[N+](=O)[O-])cnc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110230486A1,CC(=O)Cl.CC(=O)Nc1cc(C)cc(Cl)c1>>CC(=O)Nc1cc(C)c(C(C)=O)c(Cl)c1,,S=C=S,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20140024650A1,COc1ccc(B(O)O)c(F)c1F.Fc1ccc(Br)nc1>>COc1ccc(-c2ccc(F)cn2)c(F)c1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US05539112,CCCCCNc1c(F)cc(F)c2oc(-c3ccc(N(CCCN=[N+]=[N-])C(C)=O)c(F)c3)cc(=O)c12>>CCCCCNc1c(F)cc(F)c2oc(-c3ccc(NCCCN=[N+]=[N-])c(F)c3)cc(=O)c12,,C1COCCO1,Cl,O,,test
US20060045953A1,COc1ccc2c(c1)CCC2=NO>>COc1ccc2c(c1)CCC2N,[Ni],CO,,N,,test
US20120214766A1,CC(C)(C)c1cc(N)no1.O=C(Cl)c1nn(-c2ccc(F)cc2F)c2c1C[C@H]1C[C@@H]21>>CC(C)(C)c1cc(NC(=O)c2nn(-c3ccc(F)cc3F)c3c2C[C@H]2C[C@@H]32)no1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20080015232A1,CCOP(=O)(Cc1cc(OCOC)c(CC=C(C)CCC=C(C)CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)c(OCOC)c1)OCC>>CCOP(=O)(Cc1cc(OCOC)c(CC=C(C)CCC=C(C)CO)c(OCOC)c1)OCC,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110021520A1,CC(C)(C)OC(=O)NC(CO)(c1cccc(Br)c1)C(F)(F)F.CCOC(=O)C=[N+]=[N-]>>CCOC(=O)COCC(NC(=O)OC(C)(C)C)(c1cccc(Br)c1)C(F)(F)F,,ClCCl,,,,test
US20050080124A1,COc1ccc([N+](=O)[O-])cc1-c1ccnn1C(C)C.O=C1CCC(=O)N1Cl>>COc1ccc([N+](=O)[O-])cc1-c1c(Cl)cnn1C(C)C,,CN(C)C=O,,,,test
US20090253758A1,Cc1c(N[C@H](CCO[Si](C)(C)C(C)(C)C)c2nnc(-c3ccc(C#N)cc3)o2)ccc(C#N)c1Cl>>Cc1c(N[C@H](CCO)c2nnc(-c3ccc(C#N)cc3)o2)ccc(C#N)c1Cl,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20020147160A1,COCCO[C@@H]1[C@H](C)[C@@H](COC(c2ccccc2)(c2ccccc2)c2ccc(OC)cc2)O[C@H]1n1cc(C)c(=O)[nH]c1=O>>COCCO[C@@H]1[C@H](C)[C@@H](CO)O[C@H]1n1cc(C)c(=O)[nH]c1=O,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20130005707A1,COc1ccc(CN)cc1.Clc1cccc(Oc2ccccc2)n1>>COc1ccc(CNc2cccc(Oc3ccccc3)n2)cc1,,CCOC(C)=O,,,,test
US20110262359A1,CC(=O)OC(C)=O.CCOC(=O)CN(C)C(=O)[C@H](CN(C)S(=O)(=O)c1ccccc1[N+](=O)[O-])NC(=O)[C@@H](N)CCCN/C(N)=N\S(=O)(=O)c1c(C)c(C)c2c(c1C)CC(C)(C)O2>>CCOC(=O)CN(C)C(=O)[C@H](CN(C)S(=O)(=O)c1ccccc1[N+](=O)[O-])NC(=O)[C@H](CCCN/C(N)=N\S(=O)(=O)c1c(C)c(C)c2c(c1C)CC(C)(C)O2)NC(C)=O,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,,test
US20140155375A1,CI.Clc1c[nH]c2cc(Br)ccc12>>Cn1cc(Cl)c2ccc(Br)cc21,,CN(C)C=O,,[H-].[Na+],,test
US05658944,NCCc1ccc(O)cc1.O=C(Cl)OCc1ccccc1>>O=C(NCCc1ccc(O)cc1)OCc1ccccc1,,O,,O=C([O-])O.[Na+],,test
US20060009453A1,Clc1ncccc1-c1ccncn1.O=C(O)c1ccc(O)cc1>>O=C(O)c1ccc(Oc2ncccc2-c2ccncn2)cc1,,CCOC(C)=O,CS(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110230486A1,COc1ccc(Sc2cc(C)c(C(=O)CBr)c(C)c2)cc1.NC(N)=S>>COc1ccc(Sc2cc(C)c(-c3csc(N)n3)c(C)c2)cc1,,CCO,,,,test
US20150065482A1,COC(=O)c1n[nH]c2ncc(Br)cc12.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1nn(S(=O)(=O)c2ccc(C)cc2)c2ncc(Br)cc12,,CN(C)C=O,,O,[H-].[Na+],test
US06608048B2,BrCCBr.N#Cc1cnc2cc(O)c(N)cc2c1Nc1ccc(F)c(Cl)c1>>N#Cc1cnc2cc3c(cc2c1Nc1ccc(F)c(Cl)c1)NCCO3,,CCOCCO,,O=C([O-])[O-].[K+].[K+],,test
US20140296260A1,CC[C@H](N)c1nc2cccc(F)c2c(=O)n1-c1cccc(OCC(F)(F)F)c1.Clc1ncnc2[nH]ccc12>>CC[C@H](Nc1ncnc2[nH]ccc12)c1nc2cccc(F)c2c(=O)n1-c1cccc(OCC(F)(F)F)c1,,CC(C)(C)O,,CCN(C(C)C)C(C)C,,test
US20050096336A1,CCC(O)c1ccc(-c2cccc(C(F)(F)F)c2)nc1C.O=S(Cl)Cl>>CCC(Cl)c1ccc(-c2cccc(C(F)(F)F)c2)nc1C,,ClCCl,,,,test
US05240938,COC(=O)C(Cc1ccccc1)Oc1ccc(CO[Si](C)(C)C(C)(C)C)cc1>>COC(=O)C(Cc1ccccc1)Oc1ccc(CO)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20030220361A1,CC(C)(C)OC(=O)N1CCC(NC(=O)c2cc(F)cnc2Cl)CC1.Oc1ccc(F)cc1>>CC(C)(C)OC(=O)N1CCC(NC(=O)c2cc(F)cnc2Oc2ccc(F)cc2)CC1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040138195A1,CC(=O)OC(C)=O.CC(C)(C)OC(=O)N(CCC=O)c1cc(OCc2ccccc2)c2ncccc2c1I>>CC(=O)OC=CCN(C(=O)OC(C)(C)C)c1cc(OCc2ccccc2)c2ncccc2c1I,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20160257657A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.Cc1noc(C)c1CO>>Cc1noc(C)c1CS,,Cc1ccccc1,,,,test
US20080076745A1,CC(C)(C)OC(=O)NCCC[C@@H](CNC(=O)C[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NCCC[C@@H](CNC(=O)C[C@H](CCCN)NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C,[Pd],CCO,,,,test
US20160200707A1,CC(C)c1ccc(NN)cc1.O=C(Cc1ccccc1)c1ccccc1>>CC(C)c1ccc2[nH]c(-c3ccccc3)c(-c3ccccc3)c2c1,,CCO,,O=S(=O)(O)O,,test
US20110201604A1,CCn1c(Nc2nc3ccc(Cl)cc3s2)nc2cc(C(=O)O)ccc21.CN>>CCn1c(Nc2nc3ccc(Cl)cc3s2)nc2cc(C(=O)NC)ccc21,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06002008,C=CC(=O)Cl.N#Cc1cnc2ccc(N)cc2c1Nc1cccc(Cl)c1>>C=CC(=O)Nc1ccc2ncc(C#N)c(Nc3cccc(Cl)c3)c2c1,,C1CCOC1,CN(C)C=O,CCN(CC)CC,O=C([O-])O.[Na+],test
US04952571,COC(=O)CCC(=O)CBr.COc1cc(O)c(C=O)cc1OC>>COC(=O)CCC(=O)c1cc2cc(OC)c(OC)cc2o1,,CCO,O,[K+].[OH-],,test
US05889016,COC(=O)C1=C(C)NC(=O)N(C(=O)OC)C1c1cccc([N+](=O)[O-])c1>>COC(=O)C1=C(C)NC(=O)N(C(=O)OC)C1c1cccc(N)c1,,CC(=O)O,,,,test
US20100160392A1,CCOC(=O)CCCCCC(C(=O)O)c1nc(C)ns1.Nc1ccccc1>>CCOC(=O)CCCCCC(C(=O)Nc1ccccc1)c1nc(C)ns1,,ClCCl,,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160222028A1,COC(=O)c1ccc(CBr)c(Br)c1.NC(CO)C1CCOCC1>>COC(=O)c1ccc(CNC(CO)C2CCOCC2)c(Br)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20060287341A1,FC(F)(F)c1ccc(CCl)cn1.Nc1c(Cl)ncn2c(=O)[nH]nc12>>Nc1c(Cl)ncn2c(=O)n(Cc3ccc(C(F)(F)F)nc3)nc12,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100256143A1,CN(C)CCN.Clc1cc(N2CCOCC2)nc(CBr)n1>>CN(C)CCNCc1nc(Cl)cc(N2CCOCC2)n1,,CN(C)C=O,O,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],test
US20150307480A1,COC(=O)c1cc(Cl)cc(O)c1C.CS(=O)(=O)OC1CCN(c2ccncn2)CC1>>COC(=O)c1cc(Cl)cc(OC2CCN(c3ccncn3)CC2)c1C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090281075A1,C[C@H](c1cc(Cl)ccc1Cl)n1c(=O)[nH]c2cnc(NC[C@@H]3CCN(C(=O)OC(C)(C)C)C3)nc21>>C[C@H](c1cc(Cl)ccc1Cl)n1c(=O)[nH]c2cnc(NC[C@@H]3CCNC3)nc21,,ClCCl,O=C(O)C(F)(F)F,,,test
US20090176841A1,Cc1ccc(N)c2ccn(C(=O)c3ccc(O)c(C(C)C)c3)c12.O=C(O)CC(=O)OCc1ccccc1>>Cc1ccc(NC(=O)CC(=O)OCc2ccccc2)c2ccn(C(=O)c3ccc(O)c(C(C)C)c3)c12,,C1CCOC1,CCOC(C)=O,CCN=C=NCCCN(C)C,Cl,test
US20100093724A1,COC(=O)c1cc(C)nc(Br)c1>>Cc1cc(CO)cc(Br)n1,,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US20100273819A1,CCC(CC)(Oc1ccc(Cl)cc1C1CC(=O)NC(c2cc(F)ccc2C)C12C(=O)N(C(C)=O)c1cc(Cl)ccc12)C(=O)NS(C)(=O)=O.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCC(CC)(Oc1ccc(Cl)cc1C1CC(=S)NC(c2cc(F)ccc2C)C12C(=O)N(C(C)=O)c1cc(Cl)ccc12)C(=O)NS(C)(=O)=O,,Cc1ccccc1,,,,test
US20150126469A1,CC(C)CNC(=O)NCC(=O)N1CCC2(CCCN(C(=O)OCc3ccccc3)C2)CC1>>CC(C)CNC(=O)NCC(=O)N1CCC2(CCCNC2)CC1,[Pd],CCO,,C1=CCCCC1,,test
US20040176416A1,CC(C)(C)OC(=O)N1CC2CCC1CC2=Cc1ccc(Cl)c(Cl)c1>>CC(C)(C)OC(=O)N1CC2CCC1CC2Cc1ccc(Cl)c(Cl)c1,O=[Pt]=O,CCOC(C)=O,,CCO,,test
US20150133470A1,CC(=O)NC(CS)C(=O)O.O=C(Cl)OCc1ccccc1>>CC(=O)N[C@@H](CSC(=O)OCc1ccccc1)C(=O)O,,O,,C1CCOC1,O=C([O-])[O-].[Na+].[Na+],test
US08334292B1,CS(=O)(=O)Cl.C[C@@H]1CC[C@H](Nc2ncc(Br)c(OC3CNC3)n2)CC1>>C[C@@H]1CC[C@H](Nc2ncc(Br)c(OC3CN(S(C)(=O)=O)C3)n2)CC1,,ClCCl,,CCN(CC)CC,,test
US20040067878A1,Cc1cc(Cl)c2ccccc2n1.O=[Se]=O>>O=Cc1cc(Cl)c2ccccc2n1,,O,,,,test
US20130225673A1,BrBr.CCc1cc2c(C(=O)c3ccc(OC)cc3)ccc(O)c2o1>>CCc1cc2c(C(=O)c3ccc(OC)cc3)cc(Br)c(O)c2o1,,O,,,,test
US20040024058A1,CCCCC[C@H](O)[C@@H](O)/C=C/[C@@H](O)CCCCCCCC(=O)OC(C)(C)C>>CCCCC[C@H](O)[C@@H](O)/C=C/[C@@H](O)CCCCCCCC(=O)O,,CCO,O,Cl,[K+].[OH-],test
US04273704,CSCC[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)C1C2(N)CC3CC(C2)CC1(C(N)=O)C3.Cl>>CSCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)C1C2(N)CC3CC(C2)CC1(C(N)=O)C3.Cl,,C1COCCO1,CC(=O)O,,,test
US06787561B1,Cc1ccc(S(=O)(=O)OCCCCCOc2nc3ccccc3[nH]2)cc1.Sc1nc2ccccc2[nH]1>>c1ccc2[nH]c(OCCCCCSc3nc4ccccc4[nH]3)nc2c1,,CC#N,,CCN(CC)CC,O,test
US20080227782A1,CC(C)(C)OC(=O)NCc1cccc(CN)c1.O=C(O)c1cnc(-c2cccc(F)c2)nc1>>CC(C)(C)OC(=O)NCc1cccc(CNC(=O)c2cnc(-c3cccc(F)c3)nc2)c1,,C1CCOC1,CCOC(C)=O,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US20130225567A1,CC(C(=O)Nc1ccc(B(O)O)c(C#Cc2ccc3ccccc3c2)n1)N(C)C(=O)OC(C)(C)C.Cc1ncnc(C)c1Br>>Cc1ncnc(C)c1-c1ccc(NC(=O)C(C)N(C)C(=O)OC(C)(C)C)nc1C#Cc1ccc2ccccc2c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CO,O,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20150030626A1,C=CCn1c(=O)n([C@@H]2O[C@H](COC(=O)c3ccc(NNC(=O)OC(C)(C)C)nc3)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c21>>C=CCn1c(=O)n([C@@H]2O[C@H](COC(=O)c3ccc(NN)nc3)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160251311A1,CCOC(=O)C1CCCNC1.NN>>NNC(=O)C1CCCNC1,,COC(C)(C)C,,O,,test
US20070043048A1,CSc1nccc(-c2ccc(/C=C/C(C)=O)s2)n1>>CSc1nccc(-c2ccc(/C=C/C(C)O)s2)n1,,CO,,[BH4-].[Na+],,test
US20080176857A1,CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(Cl)nc2s1.NC(=O)CS>>CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(SCC(N)=O)nc2s1,,N,,CN(C)C=O,,test
US05599947,CO.O=C(O)CCCCCCBr>>COCCCCCCC(=O)O,,CO,,CN(C)C=O,,test
US20080319188A1,Nc1ccc(Oc2ccnc(N(C(=O)Oc3ccccc3)C(=O)Oc3ccccc3)c2)cc1F.O=C(O)C1(C(=O)Nc2ccc(F)cc2F)CC1>>O=C(Oc1ccccc1)N(C(=O)Oc1ccccc1)c1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4F)CC3)c(F)c2)ccn1,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20030119813A1,COc1cc2c(cc1OC)-c1cc(Cl)nc(=O)n1CC2.Cc1cc(C)c(O)c(C)c1>>COc1cc2c(cc1OC)-c1cc(Oc3c(C)cc(C)cc3C)nc(=O)n1CC2,,CC(C)O,ClCCl,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090149463A1,Cc1c(C(=O)NN2CCOCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(OCc2ccccc2)cc1>>Cc1c(C(=O)NN2CCOCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(O)cc1,,ClCCl,,BrB(Br)Br,O,test
US04336379,CCc1noc(C)c1C(C)=O.NNc1ccccc1>>CCc1noc(C)c1C(C)=NNc1ccccc1,,CCO,,Cc1ccccc1S(=O)(=O)O,,test
US20040058923A1,CCOC(=O)Cc1nc(-c2ccc(F)cc2)oc1C>>Cc1oc(-c2ccc(F)cc2)nc1CC(=O)O,,CCO,,[Na+].[OH-],,test
US05185251,CCc1cc(C#N)c(=O)[nH]c1C.ClP(Cl)(Cl)(Cl)Cl>>CCc1cc(C#N)c(Cl)nc1C,,CCCCCC,,O,,test
US09035064B2,Cc1nonc1N.O=C(O)c1c(F)cncc1F>>Cc1nonc1NC(=O)c1c(F)cncc1F,CN(C)c1ccncc1,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US20150031708A1,COc1ncc(-c2nc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)ccc2C)cc1N>>Cc1ccc(NC(=O)C2(c3ccc4c(c3)OC(F)(F)O4)CC2)nc1-c1c[nH]c(=O)c(N)c1,,C1COCCO1,,Cl,,test
US20120225062A1,COC(=O)c1cccc(-c2c(F)cc(C3=CCOCC3)cc2F)n1>>COC(=O)c1cccc(-c2c(F)cc(C3CCOCC3)cc2F)n1,[Pd],CCOC(C)=O,CO,,,test
US20070219261A1,CI.O=c1[nH]c2ccc(F)c(Cl)c2c(=O)o1>>Cn1c(=O)oc(=O)c2c(Cl)c(F)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20030045521A1,NOCC1CC1.O=S(=O)(Cl)c1ccc(F)c(F)c1F>>O=S(=O)(NOCC1CC1)c1ccc(F)c(F)c1F,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US20040110742A1,CS(=O)(=O)Cl.OCCc1ccc(N2CCOCC2)cc1>>CS(=O)(=O)OCCc1ccc(N2CCOCC2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20050227983A1,CCN1CCCC(O)C1.COc1ccc(Nc2nc(Cl)nc(NC3CCCCCC3)n2)cc1Cl>>CCN1CCCC(Oc2nc(Nc3ccc(OC)c(Cl)c3)nc(NC3CCCCCC3)n2)C1,,c1ccccc1,,[Na+].[OH-],,test
US20150274767A1,Cc1ccc(C(=O)OC[C@@H]2OC(Cl)C[C@H]2c2cc(C)ccc2C(=O)[O-])cc1.[N-]=[N+]=Nc1nc(F)nc2[nH]ccc12>>Cc1ccc(C(=O)OC[C@H]2O[C@@H](n3ccc4c(N=[N+]=[N-])nc(F)nc43)C[C@@H]2OC(=O)c2ccc(C)cc2)cc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20150158846A1,CC(=O)Cl.O=c1c2sc3c(c2cnn1-c1cc(F)cc(Br)c1CO)CCCC3>>CC(=O)OCc1c(Br)cc(F)cc1-n1ncc2c3c(sc2c1=O)CCCC3,,C1CCOC1,O,CCN(CC)CC,,test
US20160221946A1,CN(Cc1cn(S(=O)(=O)c2cccnc2)c2cc(O)ccc12)C(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(Cl)cc1F>>CN(Cc1cn(S(=O)(=O)c2cccnc2)c2cc(Oc3cc(Cl)ccc3[N+](=O)[O-])ccc12)C(=O)OC(C)(C)C,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US04018787,CCCCCCc1nnc(N)s1.O=C(Cl)Cl>>CCCCCCc1nnc(N=C=O)s1,,CCOC(C)=O,,,,test
US20150291586A1,ICCCCI.O=C1Cc2ccc(Cl)cc2N1>>O=C1Nc2cc(Cl)ccc2C12CCCC2,,C1CCOC1,,CN(C)CCN(C)C,[Li]CCCC,test
US20090233896A1,CC(=O)N1CCN(c2ccnc(Nc3ncc(-c4cncc(C(=O)NCCNC(=O)OC(C)(C)C)c4)s3)c2)CC1>>CC(=O)N1CCN(c2ccnc(Nc3ncc(-c4cncc(C(=O)NCCN)c4)s3)c2)CC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US04122179,CCCCCCC(=O)O.CC[C@@]12C=C(C(=O)OC)n3c4c(c5ccccc53)CCN(CCC1)[C@H]42>>CCCCCCC(=O)[O-].CC[C@@]12C=C(C(=O)OC)n3c4c(c5ccccc53)CCN(CCC1)[C@H]42,,O,,,,test
US04012499,O=C(O)c1ccc(-c2nnn[nH]2)cc1S(=O)(=O)c1ccccc1>>O=C1c2ccccc2S(=O)(=O)c2cc(-c3nnn[nH]3)ccc21,,O=S(=O)(O)O,,,,test
US20120142653A1,C=C(C)[C@@H]1CC[C@]2(C(=O)NCCN(C)C)CC[C@]3(C)[C@H](CC[C@H]4[C@@]3(C)CC[C@H]3C(C)(C)C(c5ccc(C(=O)OC)cc5)=CC[C@@]34C)[C@@H]12>>COC(=O)c1ccc(C2=CC[C@@]3(C)[C@@H](CC[C@]4(C)[C@@H]3CC[C@@H]3[C@H]5[C@H](C(C)C)CC[C@]5(C(=O)NCCN(C)C)CC[C@]34C)C2(C)C)cc1,[Pd],CC(=O)O,CO,,,test
US20130150391A1,COC1CCNCC1.COc1nc(Cl)nc(OC)c1[N+](=O)[O-]>>COc1nc(N2CCC(OC)CC2)nc(OC)c1[N+](=O)[O-],,C1CCOC1,O,CCN(C(C)C)C(C)C,,test
US20110224209A1,CC(C)(C)OC(=O)N[C@@H](Cc1cccs1)C(=O)N1CCC(Cc2ccc(-c3ccccc3)cc2)(C(=O)O)CC1.NCC1CCOCC1>>N[C@@H](Cc1cccs1)C(=O)N1CCC(Cc2ccc(-c3ccccc3)cc2)(C(=O)NCC2CCOCC2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040087577A1,CC(C)=CC=O.Nn1c(=O)c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2sccc21>>CC(C)=CC=Nn1c(=O)c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2sccc21,,CC(=O)N(C)C,,,,test
US20150197524A1,CC(C)I.Cn1c(=O)[nH]c2nn(Cc3ccc(-c4ccccn4)cc3)c(Nc3ccccc3)c2c1=O>>CC(C)n1c(=O)n(C)c(=O)c2c(Nc3ccccc3)n(Cc3ccc(-c4ccccn4)cc3)nc21,,CCC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US07259262B2,FS(F)(F)(F)(F)c1ccc(C=Cc2nc(CCl)co2)cc1.Oc1ccc(-c2nc(Cn3ccnn3)co2)cc1>>FS(F)(F)(F)(F)c1ccc(/C=C/c2nc(COc3ccc(-c4nc(Cn5ccnn5)co4)cc3)co2)cc1,,CCC(C)=O,,[I-].[K+],O=C([O-])[O-].[Cs+].[Cs+],test
US20130005707A1,CC(C)(C)[Si](C)(C)OCCN.COC(=O)c1cc([N+](=O)[O-])ccc1CBr>>CC(C)(C)[Si](C)(C)OCCN1Cc2ccc([N+](=O)[O-])cc2C1=O,,CO,,,,test
US20050065157A1,CC(C)Br.CCOC(=O)c1cc2c(cn1)[nH]c1ccccc12>>CCOC(=O)c1cc2c3ccccc3n(C(C)C)c2cn1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20040229864A1,C=CC(C)CO.Cc1cccc(S)c1>>C=CC(C)CSc1cccc(C)c1,,ClCCl,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04873248,Cc1cccc(-c2nc(O)cc(-c3ccccc3Cl)n2)n1.O=P(Cl)(Cl)Cl>>Cc1cccc(-c2nc(Cl)cc(-c3ccccc3Cl)n2)n1,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20140088152A1,CCOC(=O)C(Cc1ccccc1)C(=O)/C=C/c1ccc(O)c(OC)c1.NNc1ccccn1>>COc1cc(/C=C/c2nn(-c3ccccn3)c(O)c2Cc2ccccc2)ccc1O,,CC(=O)O,,,,test
US20100130495A1,COc1cc(Nc2nc3c(c(OS(=O)(=O)C(F)(F)F)n2)CN(C(=O)OC(C)(C)C)CC3)ccc1-n1cnc(C)c1.Nc1ccccc1>>COc1cc(Nc2nc3c(c(Nc4ccccc4)n2)CNCC3)ccc1-n1cnc(C)c1,,CN(C)C=O,,Cl,,test
US20130231328A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CNC(=O)CN>>CNC(=O)CNC(=O)OC(C)(C)C,,C1CCOC1,O,Cl,[Na+].[OH-],test
US20090186879A1,NCCCCCO.O=[N+]([O-])c1cccc([N+](=O)[O-])c1Cl>>O=[N+]([O-])c1cccc([N+](=O)[O-])c1NCCCCCO,,CCOC(C)=O,,C1CCOC1,CCN(CC)CC,test
US20110230458A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](O)CC1.CCCCc1nnc(Cl)cc1-c1ccc(OC2CCCCC2)cc1>>CCCCc1nnc(O[C@@H]2CC[C@@H](NC(=O)OC(C)(C)C)CC2)cc1-c1ccc(OC2CCCCC2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20050227983A1,COc1ccc(Nc2nc(Cl)nc(NC3CCCCCC3)n2)cc1Cl.O=Cc1ccc(O)cc1>>COc1ccc(Nc2nc(NC3CCCCCC3)nc(Oc3ccc(C=O)cc3)n2)cc1Cl,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US06316389B1,CCOC(=O)Cl.CON=C(C#CCN1CCOCC1)C(=O)OC>>CON=C(C#CCCl)C(=O)OC,,C1CCOC1,,,,test
US06518273B1,COc1ccccc1N1CCN(C(=O)CCc2c(-c3ccc(Cl)c(Cl)c3)[nH]c3ccccc23)CC1.CS(=O)(=O)Cl>>COc1ccccc1N1CCN(C(=O)CCc2c(-c3ccc(Cl)c(Cl)c3)n(S(C)(=O)=O)c3ccccc23)CC1,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20150232468A1,CCCCCCCCCCCC(=O)Cl.C[C@H]1C2N(C(=O)NCc3ccccc3)CCC(=O)N2[C@@H](Cc2ccc(O)cc2)C(=O)N1Cc1cccc2ccccc12>>CCCCCCCCCCCC(=O)Oc1ccc(C[C@H]2C(=O)N(Cc3cccc4ccccc34)[C@@H](C)C3N(C(=O)NCc4ccccc4)CCC(=O)N32)cc1,,CCOC(C)=O,,C1CCOC1,CCN(CC)CC,test
US20070179173A1,C1CCNCC1.O=C1CCc2c(C3OCCO3)cccc2N1Cc1cccc(CCl)n1>>O=C1CCc2c(C3OCCO3)cccc2N1Cc1cccc(CN2CCCCC2)n1,,CCOC(C)=O,,CC(=O)O,O,test
US20120083475A1,CCOC(=O)C(N)=NO.O=C(O)Cc1ccccc1F>>CCOC(=O)c1noc(Cc2ccccc2F)n1,CN(C)C=O,ClCCl,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20060025459A1,Br.Nc1cc(C(=O)O)cc([N+](=O)[O-])c1>>O=C(O)c1cc(Br)cc([N+](=O)[O-])c1,,O,,O=N[O-].[Na+],,test
US20140274930A1,CC(=O)Cl.CNC(=O)c1cccc(-c2ccc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@]3(O)CN)c(C)c2)c1>>CNC(=O)c1cccc(-c2ccc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@]3(O)CNC(C)=O)c(C)c2)c1,,C1CCOC1,,CC(=O)[O-].[Na+],,test
US04221788,O=C1CCCCC(Cc2ccc(Cl)cc2)N1>>Clc1ccc(CC2CCCCCN2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20020107278A1,O=C(c1ccccc1)N1CCc2[nH]c3cccc(Oc4ccccc4)c3c2CC1>>c1ccc(CN2CCc3[nH]c4cccc(Oc5ccccc5)c4c3CC2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04097669,FC(F)(F)c1nnc(Br)s1.NC(N)=S>>FC(F)(F)c1nnc(S)s1,,CCO,O,Cl,[K+].[OH-],test
US04139538,O=C1NC(C(=O)c2ccc(Cl)cc2)CO1>>O=C1NC(C(O)c2ccc(Cl)cc2)CO1,,CCO,,[BH4-].[Na+],[Cl-].[NH4+],test
US20100267943A1,C=CC/C(C)=C\C[C@H](O[Si](C)(C)C(C)(C)C)C(=O)N(C)OC.C[Mg]Cl>>C=CC/C(C)=C\C[C@H](O[Si](C)(C)C(C)(C)C)C(C)=O,,C1CCOC1,,,,test
US20050277652A1,CN(C)CCN1CCN(C(=O)Nc2cc(Oc3ccc(N)cc3)ccn2)CC1.O=C(Cc1ccccc1)N=C=S>>CN(C)CCN1CCN(C(=O)Nc2cc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3)ccn2)CC1,,CCO,Cc1ccccc1,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US20090111800A1,Cc1cc(O)cc(C)c1C[C@@H]1CCN(C2CCc3n[nH]cc3C2)C1=O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>Cc1cc(OS(=O)(=O)C(F)(F)F)cc(C)c1C[C@@H]1CCN(C2CCc3nn(S(=O)(=O)C(F)(F)F)cc3C2)C1=O,,c1ccncc1,,,,test
US20140288045A1,C=CC(=O)N1CCNCC1.Cc1cc(=O)n(CCC(=O)O)cc1Br>>C=CC(=O)N1CCN(C(=O)CCn2cc(Br)c(C)cc2=O)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150368295A1,C#CC(C)(C)O.O=c1c[n+](-c2ccccc2)[n-]o1>>CC(C)(O)c1cnn(-c2ccccc2)c1,,C1CCCCC1,CCOC(C)=O,,,test
US05246935,COc1cc(N)cc(OC)c1OC.S=C(Cl)Cl>>COc1cc(N=C=S)cc(OC)c1OC,,Cc1ccccc1,,CCN(CC)CC,,test
US20090264406A1,Cn1cnc2ccc(C(O)c3cnc4ccc(Cl)nn34)cc21>>Cn1cnc2ccc(C(=O)c3cnc4ccc(Cl)nn34)cc21,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05942617,BrCc1ccccc1.CC(=O)[C@@]1(n2cnc3c(=O)[nH]c(N)nc32)O[C@H](CO)[C@](O)(C(C)=O)[C@]1(O)C(C)=O>>Nc1nc2ncn(Cc3ccccc3)c2c(=O)[nH]1,,CC#N,,Cl,,test
US20070179165A1,Cc1ccc(-n2cnc(Br)c2C(=O)O)c(C)c1.O=S(Cl)Cl>>Cc1ccc(-n2cnc(Br)c2C(=O)Cl)c(C)c1.Cl,CN(C)C=O,,,,,test
US20040110804A1,CN1CC(C(=O)N(Cc2ccc(F)cc2)OCC(=O)OC(C)(C)C)=C(O)C1=O>>CN1CC(C(=O)N(Cc2ccc(F)cc2)OCC(=O)O)=C(O)C1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110212918A1,COc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c(CC(=O)O)c1>>O=C(O)Cc1cc(O)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2,,ClCCl,,BrB(Br)Br,,test
US20150011773A1,BrCc1ccc(CBr)cc1.CC(C)(C)OC(=O)CC[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N[C@@H](C[C@H](Cc1ccc(CBr)cc1)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,C1CCOC1,,Cl,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20100286123A1,CCOC(=O)C(C)c1ccc(C#N)c(OC)c1>>COc1cc(C(C)CO)ccc1C#N,,C1CCOC1,,O,[BH4-].[Li+],test
US20050171154A1,CI.Nc1ccc(N2CCCCC2=S)cc1>>CSC1=[N+](c2ccc(N)cc2)CCCC1.[I-],,CC(C)=O,,,,test
US20140171420A1,CC(C)c1c(N2CCC(Br)C2=O)cnn1-c1ccc(F)cc1.N#Cc1n[nH]c2ncccc12>>CC(C)c1c(N2CCC(n3nc(C#N)c4cccnc43)C2=O)cnn1-c1ccc(F)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120252815A1,CC(=O)OCCCCBr.CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCCC(N)C4)n3)ccc21>>CC1(C)CCC(C)(C)c2cc(-c3csc(N4CCCC(NCCCCO)C4)n3)ccc21,,CO,,Cl,[Na+].[OH-],test
US20100068301A1,CCOC(=O)C(C)(C)Cc1c(SC(C)(C)C)c2cc(OCc3ccc(C)cn3)ccc2n1Cc1ccc(-c2ccc(CO)cn2)cc1>>Cc1ccc(COc2ccc3c(c2)c(SC(C)(C)C)c(CC(C)(C)C(=O)O)n3Cc2ccc(-c3ccc(CO)cn3)cc2)nc1,,C1CCOC1,,CO,[Li+].[OH-],test
US20050113419A1,CCCc1c(OCCCN(C)C(=O)Nc2ccc(C(=O)OC)cn2)ccc2c(C(F)(F)F)noc12>>CCCc1c(OCCCN(C)C(=O)Nc2ccc(C(=O)O)cn2)ccc2c(C(F)(F)F)noc12,,C1CCOC1,CO,[Na+].[OH-],,test
US20140371219A1,CC(=O)OCc1csc2cncnc12>>OCc1csc2cncnc12,,C1CCOC1,O,[Na+].[OH-],,test
US20130150343A1,Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(CN5CCN(C)C(CO[Si](C(C)C)(C(C)C)C(C)C)C5)n4c3)c3ccccc32)cc1>>Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)N[C@H]2CC[C@@H](Oc3ccc4nnc(CN5CCN(C)C(CO)C5)n4c3)c3ccccc32)cc1,,C1CCOC1,O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20080045536A1,CNS(=O)(=O)c1ccc(N)cc1.Clc1cc(Br)c2ncc(Br)n2n1>>CNS(=O)(=O)c1ccc(Nc2cc(Cl)nn3c(Br)cnc23)cc1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20070249607A1,CC(C)(C)OC(=O)N1CCC(COCc2cc(Br)cc(C(F)(F)F)c2)(c2ccccc2F)CC1.N#Cc1ccc(B(O)O)cc1>>CC(C)(C)OC(=O)N1CCC(COCc2cc(-c3ccc(C#N)cc3)cc(C(F)(F)F)c2)(c2ccccc2F)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,CO,[K+].[OH-],test
US20160194290A1,C=CC(C(C)C)C(C)(NC(=O)NCCC(=O)OCC)c1ccc(CCC(C)(C)C)c(Cl)c1>>CCOC(=O)CCN1C=C(C(C)C)C(C)(c2ccc(CCC(C)(C)C)c(Cl)c2)NC1=O,,CO,,CSC,,test
US05587392,COCOc1ccc(C(F)(F)F)cc1C=O>>COCOc1ccc(C(F)(F)F)cc1CO,,CO,,[BH4-].[Na+],,test
US20080293776A1,O=C1CCC(=O)N1Br.Oc1ccc2c(c1)CCC2>>Oc1cc2c(cc1Br)CCC2,,CN(C)C=O,,O,,test
US20150166549A1,BrP(Br)Br.CC(O)c1oc(=O)c2ccccc2c1Cc1ccccc1>>CC(Br)c1oc(=O)c2ccccc2c1Cc1ccccc1,,ClCCl,,,,test
US20120101136A1,CCOC(=O)CBr.CCc1cc(O)ccc1-c1noc(-c2ccc(OC(C)C)c(Cl)c2)n1>>CCOC(=O)COc1ccc(-c2noc(-c3ccc(OC(C)C)c(Cl)c3)n2)c(CC)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US05763700,COC(=O)C(F)=CC1(c2ccc(Cl)cc2)CC1>>OCC(F)=CC1(c2ccc(Cl)cc2)CC1,,CCOCC,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20070203156A1,COc1ncc(-c2cnc(C(=O)CCCCCCc3ccccc3)o2)c(OC)n1>>O=C(CCCCCCc1ccccc1)c1ncc(-c2c[nH]c(=O)[nH]c2=O)o1,,CCOC(C)=O,,,,test
US20110065681A1,Cc1ccc(CN=[N+]=[N-])cc1S(C)(=O)=O>>Cc1ccc(CN)cc1S(C)(=O)=O,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090099175A1,COc1cc2cn[nH]c(=O)c2cc1OC.O=P(Br)(Br)Br>>COc1cc2cnnc(Br)c2cc1OC,,CO,ClCCl,CC#N,,test
US20160176850A1,N#CC1(COc2nc(Cl)nc(Cl)n2)CC1.Nc1ncncc1OCC1CCNCC1>>N#CC1(COc2nc(Cl)nc(N3CCC(COc4cncnc4N)CC3)n2)CC1,,C1CCOC1,CO,CCN(C(C)C)C(C)C,Cl,test
US20150376221A1,CCOP(C)(=O)OCC.C[C@@H]1OC(=O)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@@H]1OCc1ccccc1>>CCOP(=O)(C[C@@]1(O)O[C@@H](C)[C@@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1)OCC,,C1CCOC1,,[Li]CCCC,,test
US06121272,COc1ccc(S(=O)(=O)Cl)cc1.O[C@H]1CCNC1>>COc1ccc(S(=O)(=O)N2CC[C@H](O)C2)cc1,,C1COCCO1,O,CCN(CC)CC,Cl,test
US04576940,CC(=O)Oc1ccc2c(c1)c(C(=O)NC1CCN(CCc3ccccc3)CC1)c(C)n2C(C)C.Cl>>Cc1c(C(=O)NC2CCN(CCc3ccccc3)CC2)c2cc(O)ccc2n1C(C)C.Cl,,CO,O,[Na+].[OH-],,test
US20080242683A1,CCn1nnc([C@H]2O[C@@H](n3cnc4c(NCC(c5ccccc5)c5ccccc5)nc(N5CC[C@@H](NC(=O)C(=O)OC)C5)nc43)[C@H](O)[C@@H]2O)n1>>CCn1nnc([C@H]2O[C@@H](n3cnc4c(NCC(c5ccccc5)c5ccccc5)nc(N5CC[C@@H](NC(=O)C(=O)O)C5)nc43)[C@H](O)[C@@H]2O)n1,,CO,,[K+].[OH-],,test
US20130065893A1,C=C[Mg]Br.N#Cc1ccc([C@H]2CC(=O)c3cncn32)c(F)c1>>C=C[C@@]1(O)C[C@H](c2ccc(C#N)cc2F)n2cncc21,,C1CCOC1,,,,test
US20080249309A1,BrBr.OCc1c2ccccc2cc2ccccc12>>BrCc1c2ccccc2cc2ccccc12,,CC#N,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140031391A1,CCOC(=O)c1ccc2c(n1)CCCC2N(CCc1ccccc1O)C(=O)OC(C)(C)C.FC(F)(F)c1ccc(CCc2ccc(CCl)cc2)cc1>>CCOC(=O)c1ccc2c(n1)CCCC2N(CCc1ccccc1OCc1ccc(CCc2ccc(C(F)(F)F)cc2)cc1)C(=O)OC(C)(C)C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05541339,CCOC(=O)c1cc2ccccc2n1NC(=O)c1ccc(C(=O)Nn2c(C(=O)OCC)cc3ccccc32)[nH]1>>O=C(Nn1c(C(=O)O)cc2ccccc21)c1ccc(C(=O)Nn2c(C(=O)O)cc3ccccc32)[nH]1,,c1ccncc1,,[Na+].[OH-],,test
US20110118234A1,CC(C)CI.O=C(O)Cc1cccc(Br)c1>>CC(C)CC(C(=O)O)c1cccc(Br)c1,,Cc1ccccc1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US04598067,CCOC(=O)CN(Cc1ccccc1)C(=O)[C@@H]1CCC(=O)N1>>O=C(O)CN(Cc1ccccc1)C(=O)[C@@H]1CCC(=O)N1,,CO,,[Na+].[OH-],,test
US20020188125A1,CC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)OCC[C@@H](CO)Cn1cnc2c(=O)[nH]c(N)nc21.CCCC(=O)O>>CCCC(=O)OC[C@H](CCOC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)Cn1cnc2c(=O)[nH]c(N)nc21,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20030018016A1,COc1cc(CC(=O)OC(C)(C)C)ccc1N.O=C=Nc1ccccc1>>COc1cc(CC(=O)OC(C)(C)C)ccc1NC(=O)Nc1ccccc1,,ClCCl,,,,test
US20030186971A1,COC(=O)c1ccccc1S.N#Cc1cccnc1>>O=c1nc(-c2cccnc2)sc2ccccc12,,Cc1ccccc1,,CCN(CC)CC,,test
US20130123235A1,BrC(Br)(Br)Br.CCCC[Sn](/C=C\CO)(CCCC)CCCC>>CCCC[Sn](/C=C\CBr)(CCCC)CCCC,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US06319920B1,CCN(CC1CCN(C(=O)CCN)CC1)[C@@H](C)Cc1ccc2c(c1)CCO2.CS(=O)(=O)Cl>>CCN(CC1CCN(C(=O)CCNS(C)(=O)=O)CC1)[C@@H](C)Cc1ccc2c(c1)CCO2,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20150344471A1,N#Cc1ccc(C(=O)N(c2ccn3nccc3c2)C2CC2)nc1.O=C1CCC(=O)N1Br>>N#Cc1ccc(C(=O)N(c2ccn3ncc(Br)c3c2)C2CC2)nc1,,CCOC(C)=O,,,,test
US05840732,CCOC(=O)C(C(=O)OCC)C(C)C.NC(=O)NCc1ccccc1>>CC(C)C1C(=O)NC(=O)N(Cc2ccccc2)C1=O,,CO,,C[O-].[Na+],,test
US20110312944A1,CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2)no1.O=C(Cl)CCl>>CC(C)(C)c1cc(NC(=O)[C@@H]2CCCCN2C(=O)CCl)no1,,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US04665073,C=C(Cl)C#N.CCN(CC)CC.N=C(N)CCl>>Nc1ccnc(CCl)c1,,CCO,,Cl,,test
US20100256092A1,C1=COCCC1.O=Cc1ccc(O)cc1O>>O=Cc1ccc(OC2CCCCO2)cc1O,,ClCCl,,,,test
US20140107139A1,COc1ccc2c(c1)C(C)(C)COC2>>CC1(C)COCc2ccc(O)cc21,,ClCCl,,BrB(Br)Br,O,test
US20110263545A1,CC(=O)Nc1ccc(OC(=O)C(CSSCC(NC(=O)OC(C)(C)C)C(=O)O)NC(=O)OC(C)(C)C)cc1.ClCCl>>CC(=O)Nc1ccc(OC(=O)C(N)CSSCC(N)C(=O)O)cc1.Cl.Cl,,CCOCC,,CO,,test
US04032639,O=C1Nc2ccccc2N2CCN(C(=O)OCc3ccccc3)CC12>>O=C1Nc2ccccc2N2CCNCC12,[Pd],CCO,,Cl,[H][H],test
US20140256719A1,CC(C)(C)NS(=O)(=O)c1cc(Br)cnc1O.COc1ccc(CCl)cc1>>COc1ccc(COc2ncc(Br)cc2S(=O)(=O)NC(C)(C)C)cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04474754,CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)ON1C(=O)CCC1=O.CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)O>>CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)O,,CN(C)C=O,,CCN(CC)CC,,test
US04579851,C1=CCNC=C1.ClC(Cl)Cl.ClCCl.O=C(O)C(F)(F)F>>CC(Cl)Cl.COc1ccccc1,,ClC(Cl)Cl,,N#N,,test
US04514410,BrBr.CC(=O)c1c(F)cccc1F.CSC>>C[S+](C)CC(=O)c1c(F)cccc1F.[Br-],,CCOCC,ClCCl,,,test
US20040235891A1,Fc1ccc(CCC2=NCCc3cc4c(cc32)OCO4)cc1>>Fc1ccc(CCC2NCCc3cc4c(cc32)OCO4)cc1,,CO,,[BH4-].[Na+],,test
US20140066425A1,CC(C)(C)OC(=O)n1ccnc1CCCc1ccc([N+](=O)[O-])cc1F>>CC(C)(C)OC(=O)n1ccnc1CCCc1ccc(N)cc1F,[Pd],CCOC(C)=O,,,,test
US20080070928A1,O=[N+]([O-])c1ccc(Oc2cccnc2)c(Cl)c1Oc1cccnc1>>Nc1ccc(Oc2cccnc2)c(Cl)c1Oc1cccnc1,[Fe],CO,O,[Cl-].[NH4+],,test
US20130109711A1,O=C1NCCCC12CCCNC2.O=S(=O)(Cl)c1cc(F)cc(C(F)(F)F)c1>>O=C1NCCCC12CCCN(S(=O)(=O)c1cc(F)cc(C(F)(F)F)c1)C2,,ClCCl,,CCN(CC)CC,Cl,test
US20160228562A1,CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO)O[C@H]1n1cccnc1=O.CCCC(=O)OC(=O)CCC>>CCCC(=O)OC[C@H]1O[C@@H](n2cccnc2=O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C,CN(C)c1ccncc1,c1ccncc1,,,,test
US20120149707A1,CO/C=C(/C(=O)OC)c1ccccc1COc1cc(C)c(C(=O)COC)cc1C.CON>>CO/C=C(/C(=O)OC)c1ccccc1COc1cc(C)c(/C(COC)=N/OC)cc1C,,CO,,Cl,,test
US20030225266A1,CC(=O)Cl.CC(CNS(=O)(=O)C(C)C)Oc1ccc(-c2ccc(CN)cc2)cc1>>CC(=O)NCc1ccc(-c2ccc(OC(C)CNS(=O)(=O)C(C)C)cc2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20070293530A1,CC(C)(C)OC(=O)NS(=O)(=O)NCCCC[C@H](N)C(=O)Nc1cccc2cccnc12.O=C=NCc1ccccc1>>CC(C)(C)OC(=O)NS(=O)(=O)NCCCC[C@H](NC(=O)NCc1ccccc1)C(=O)Nc1cccc2cccnc12,,ClCCl,,CCN(CC)CC,,test
US20160272596A1,COc1ccc2ccccc2c1CN1C(=O)[C@@H](NC(=O)[C@H](C)NC(=O)OC(C)(C)C)CN(C(=O)c2ccc(N)cc2)c2ccccc21>>COc1ccc2ccccc2c1CN1C(=O)[C@@H](NC(=O)[C@H](C)N)CN(C(=O)c2ccc(N)cc2)c2ccccc21,,C1COCCO1,Cl,,,test
US20080039459A1,C1COCCN1.Clc1nc(Cl)c2sccc2n1>>Clc1nc(N2CCOCC2)c2sccc2n1,,CO,,,,test
US20060276481A1,Fc1ccc2ncccc2c1.OO>>[O-][n+]1cccc2cc(F)ccc21,,CC(=O)O,,,,test
US06995143B2,CNC(C)O.Nc1ncnc2c1ncn2CCCl>>CC(O)N(C)CCn1cnc2c(N)ncnc21,,CCCCO,,,,test
US04557753,Cn1nccc1O.O=C(Cl)c1ccc(Cl)cc1Cl>>Cn1nccc1OC(=O)c1ccc(Cl)cc1Cl,,ClC(Cl)Cl,,[Na+].[OH-],,test
US20140357665A1,C[C@H]1CCCC(C)(C)[C@@H]1[C@@](C)(O)c1ccc2c(c1)CCNC2.C[Si](C)(C)N=C=O>>C[C@H]1CCCC(C)(C)[C@@H]1[C@@](C)(O)c1ccc2c(c1)CCN(C(N)=O)C2,,ClCCl,,CCN(CC)CC,,test
US20040044037A1,C1CNCCN1.CC(C)(C)OC(=O)N=C(NCc1cccc2ccccc12)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N=C(NCc1cccc2ccccc12)NC(=O)N1CCNCC1,,C1CCOC1,,,,test
US20080119442A1,COC(=O)c1ccc2c([N+](=O)[O-])cc3c(c2c1)C(CCl)CN3C(=O)C(F)(F)F>>COC(=O)c1ccc2c([N+](=O)[O-])cc3c(c2c1)C(CCl)CN3,,CO,ClCCl,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20090099156A1,CC(C)(C)OC(=O)N1CCOC(C(=O)N2CCN(C(=O)Nc3ccc(Cl)c(Cl)c3)CC2)C1>>O=C(Nc1ccc(Cl)c(Cl)c1)N1CCN(C(=O)C2CNCCO2)CC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20080188528A1,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2.O=C(O)c1cccn(Cc2ccccc2-c2ccc(F)cc2)c1=O>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)c2cccn(Cc3ccccc3-c3ccc(F)cc3)c2=O)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100063038A1,C=C[Mg]Br.Nc1ncnn2c(C=O)cc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)c(F)c3)c12>>C=CC(O)c1cc(-c2ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)c(F)c2)c2c(N)ncnn12,,C1CCOC1,,,,test
US04435422,CCOC(=O)C1Cc2cc(C(=O)c3ccc(O)c(CN)c3)c(Cl)c(Cl)c2O1.Cl>>Cl.NCc1cc(C(=O)c2cc3c(c(Cl)c2Cl)OC(C(=O)O)C3)ccc1O,,CCO,,,,test
US20090325900A1,COc1ccc(F)c(F)c1.O=C1CCC1>>COc1ccc(F)c(F)c1C1(O)CCC1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20110130409A1,CCOC(=O)CC1CCc2c1[nH]c1ccc(OCc3ccc(S(C)(=O)=O)cc3)cc21>>CS(=O)(=O)c1ccc(COc2ccc3[nH]c4c(c3c2)CCC4CC(=O)O)cc1,,C1COCCO1,,[Li+].[OH-],,test
US06713473B1,CCI.COC(=O)c1ccc2[nH]c3c(c2c1)CCCC3>>CCn1c2c(c3cc(C(=O)OC)ccc31)CCCC2,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20090036472A1,CS(=O)(=O)c1ncc2cc(Oc3ccccc3F)c(=O)n(C3CC3)c2n1.NN1CC2CCCC2C1>>O=c1c(Oc2ccccc2F)cc2cnc(NN3CC4CCCC4C3)nc2n1C1CC1,,O,,CCN(C(C)C)C(C)C,,test
US06187805B1,CN(C)CCc1cn(C(=O)OC(C)(C)C)c2ccc(OCc3ccccc3)cc12>>CN(C)CCc1cn(C(=O)OC(C)(C)C)c2ccc(O)cc12,[Pd],CCO,,Cl,,test
US20060148858A1,CCOC(=O)CCc1cc(O)nn1-c1ccccc1.CCOc1nn(Cc2ccccc2)cc1CCCCO>>CCOC(=O)CCc1cc(OCCCCc2c[nH]nc2OCC)nn1-c1ccccc1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US05574042,Cc1cn2cccc(OCc3c(Cl)ccc(N4CCCC4=O)c3Cl)c2n1>>Cc1cn2cccc(OCc3c(Cl)ccc(N4CCCC4)c3Cl)c2n1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],[Cl-].[NH4+],test
US20160090387A1,Cn1cnc2c(Cl)nc(Cl)nc21.NCc1cccnc1>>Cn1cnc2c(NCc3cccnc3)nc(Cl)nc21,,CCCCO,,CCN(CC)CC,,test
US20080009530A1,BrCc1ccccc1.CCOC(=O)CCc1ccc(OCCOC)cc1O>>CCOC(=O)CCc1ccc(OCCOC)cc1OCc1ccccc1,,CCOC(C)=O,CN(C)C=O,[Cl-].[NH4+],O=C([O-])[O-].[K+].[K+],test
US20040138462A1,COc1ccc(S(=O)(=O)c2ccc(CCNCc3ccccc3)cc2)cc1>>O=S(=O)(c1ccc(O)cc1)c1ccc(CCNCc2ccccc2)cc1,,ClCCl,,BrB(Br)Br,,test
US20110021352A1,O=C(Cl)C(=O)Cl.O=C(O)c1cc2cccnc2nc1C(F)(F)F>>O=C(Cl)c1cc2cccnc2nc1C(F)(F)F,,ClCCl,,CN(C)C=O,,test
US20030195176A1,CC(C)(C)[Si](C)(C)O[C@H]1C[C@H](O[Si](C)(C)C(C)(C)C)CC2=CC=C3[C@@H]4CC=C(CO)[C@@]4(C)CC[C@@H]3[C@]21C.CC1(C)OC1CBr>>CC1(C)OC1COCC1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US05563141,CC(=O)c1ccc(CCN)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>CC(=O)c1ccc(CCNS(=O)(=O)c2ccc(C)cc2)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US20080269288A1,C1CCOC1.CCOC(C)=O.O=C(NC1C2CC3CC1CC(O)(C3)C2)c1ccc(Cl)nc1Cl>>CCCOc1nc(Cl)ccc1C(=O)NC1C2CC3CC1CC(O)(C3)C2,,CCOC(C)=O,,,,test
US04428949,CC(CF)(CF)C(=O)CBr.Oc1cccc(C(F)(F)F)c1>>CC(CF)(CF)C(=O)COc1cccc(C(F)(F)F)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06297197B1,COC(=O)c1nc(Br)cc(Br)c1OC.[N-]=[N+]=[N-]>>COC(=O)c1nc(Br)cc(N=[N+]=[N-])c1OC,,CN(C)C=O,,O,,test
US05086062,Cc1cccc(C(=O)O)c1>>CC1CCCC(C(=O)O)C1,O=[Pt],CC(=O)O,,,,test
US20040053943A1,CCI.Oc1ccc2cc(Br)ccc2c1>>CCOc1ccc2cc(Br)ccc2c1,,CN(C)C=O,,O,[H-].[Na+],test
US20040204584A1,COc1ccc(C2COCCO2)c2sc(N)nc12.O=C(O)c1ccc2c(c1)OCO2>>COc1ccc(C2COCCO2)c2sc(NC(=O)c3ccc4c(c3)OCO4)nc12,,C1CCOC1,ClC(Cl)Cl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130072467A1,FC(F)(F)c1ccc(CBr)c(C(F)(F)F)c1.OCC1CCCNCC1>>OCC1CCCN(Cc2ccc(C(F)(F)F)cc2C(F)(F)F)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04640703,CC(Oc1ccc(Oc2ncc(Cl)cc2F)cc1)C(=O)Cl.CCCCNC#N>>CCCCN(C#N)C(=O)C(C)Oc1ccc(Oc2ncc(Cl)cc2F)cc1,,Cc1ccccc1,,CCN(CC)CC,,test
US20140045872A1,Cc1ccncc1I.O=C1NCCc2scc(-c3ccc(F)cc3)c21>>Cc1ccncc1N1CCc2scc(-c3ccc(F)cc3)c2C1=O,I[Cu]I,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20090306403A1,ClC/C=C\CCl.NCc1ccc(F)cc1>>Fc1ccc(CN2CC=CC2)cc1,,ClCCl,,,,test
US20060040956A1,Nc1ncccc1C(=O)Nc1ccc(C(F)(F)C(F)(F)F)cc1.O=Cc1ccncn1>>O=C(Nc1ccc(C(F)(F)C(F)(F)F)cc1)c1cccnc1NCc1ccncn1,,CS(C)=O,,[BH4-].[Na+],,test
US20130225620A1,CSC(=S)OC1(c2cc(-n3c(C)ccc3C)nn2COCC[Si](C)(C)C)COC1>>Cc1ccc(C)n1-c1cc(C2COC2)n(COCC[Si](C)(C)C)n1,,Cc1ccccc1,,CC(C)(C#N)N=NC(C)(C)C#N,CCCC[SnH](CCCC)CCCC,test
US05654316,COc1ccc(N(C)C(=O)CC(CCO)c2ccc(Cl)c(Cl)c2)cc1.CS(=O)(=O)Cl>>COc1ccc(N(C)C(=O)CC(CCOS(C)(=O)=O)c2ccc(Cl)c(Cl)c2)cc1,,ClCCl,,CCN(CC)CC,,test
US20090318405A1,N#CCC1(n2cc(-c3ccnc(Cl)n3)cn2)CC(C#N)C1.Nc1ccc(C(=O)O)cc1>>N#CCC1(n2cc(-c3ccnc(Nc4ccc(C(=O)O)cc4)n3)cn2)CC(C#N)C1,,C1COCCO1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05053525,COC(=O)CC1CC(CCc2c(C)cc(C)cc2-c2ccc(F)c(C)c2)=NO1.OB(O)O>>COC(=O)CC(O)CC(=O)CCc1c(C)cc(C)cc1-c1ccc(F)c(C)c1,[Pd],CO,O,,,test
US20040248983A1,COc1cc(CC(=O)Nc2cccc(I)c2)ccc1OCCNC(=O)OC(C)(C)C.OB(O)c1ccccc1>>COc1cc(CC(=O)Nc2cccc(-c3ccccc3)c2)ccc1OCCNC(=O)OC(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20160009752A1,CC(=NO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C.ClCCN1CCCC1>>CC(=NOCCN1CCCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C,,CN(C)C=O,,Cl,[H-].[Na+],test
US20080064678A1,COc1ccc2cc(-c3cccc(Cl)c3)n(CC(=O)NC(C)C)c(=O)c2c1>>CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)cc2ccc(O)cc2c1=O,,ClCCl,,BrB(Br)Br,,test
US20130065877A1,CS(=O)(=O)Cl.O=C(Nc1ccc([C@H]2CCC(O)C2)cc1)OCc1ccccc1>>CS(=O)(=O)O[C@H]1CCC(c2ccc(NC(=O)OCc3ccccc3)cc2)C1,,CCCCCCC,ClCCl,CCN(CC)CC,CCOC(C)=O,test
US20130131039A1,CCSc1nc(N)cc(-c2ccc(Br)cc2)n1.COC(CBr)OC>>CCSc1nc(-c2ccc(Br)cc2)cc2nccn12,,C1CCOC1,O,,,test
US20110098297A1,CC(O)CO[Si](c1ccccc1)(C(C)(C)C)C(C)(C)C.CCOC(=O)c1cc2cc(Oc3ccc(S(C)(=O)=O)cc3)cc(O)c2[nH]1>>CCOC(=O)c1cc2cc(Oc3ccc(S(C)(=O)=O)cc3)cc(OC(C)CO[Si](c3ccccc3)(C(C)(C)C)C(C)(C)C)c2[nH]1,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20090005346A1,CC(C)N(c1ncn(C[C@@H](CO)OCP(=O)(O)O)c(=O)n1)C(C)C>>Nc1ncn(C[C@@H](CO)OCP(=O)(O)O)c(=O)n1,,CC#N,,C[Si](C)(C)Br,,test
US20120053205A1,COc1nc2cc(C(F)(F)F)ccc2c(C)c1C(=O)O.NCc1ccc(F)cc1>>COc1nc2cc(C(F)(F)F)ccc2c(C)c1C(=O)NCc1ccc(F)cc1,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040082642A1,CC[Mg]Cl.O=C1c2cc(O)ccc2CC12Cc1ccc(O)cc1C2>>CCC1(O)c2cc(O)ccc2CC12Cc1ccc(O)cc1C2,,C1CCOC1,,CCOC(C)=O,[Cl-].[NH4+],test
US20060111375A1,COc1cc2c(Oc3cc4cccnc4nc3C)ccnc2cc1O.OCCCBr>>COc1cc2c(Oc3cc4cccnc4nc3C)ccnc2cc1OCCCO,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20120101083A1,CC(C)Oc1ncc(C(=O)Cl)cc1C#N.Cc1c(C(=N)NO)ccc2c1CCN(C(=O)OC(C)(C)C)C2>>Cc1c(-c2noc(-c3cnc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(C(=O)OC(C)(C)C)C2,,Cc1ccccc1,c1ccncc1,,,test
US04540787,CCC=O.COc1ccc2c(c1)CCCN2>>CCCN1CCCc2cc(OC)ccc21,[Pd],CCO,,,,test
US20090270405A1,Cc1cc(C)c2cnc(N)cc2c1.O=c1ccccn1C(=S)n1ccccc1=O>>Cc1cc(C)c2cnc(N=C=S)cc2c1,,ClCCl,,,,test
US20040127570A1,COC(=O)CBr.COC(=O)c1ccc2cc(O)ccc2c1>>COC(=O)COc1ccc2cc(C(=O)OC)ccc2c1,,CC(C)=O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080194616A1,CCCCc1nc2ccccn2c(=O)c1-c1ccc(O)cc1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCCCc1nc2ccccn2c(=O)c1-c1ccc(OS(=O)(=O)C(F)(F)F)cc1,,ClCCl,,CCN(CC)CC,,test
US20100216788A1,O=[N+]([O-])c1ccc2c(ccn2Cc2cccc(OC(F)(F)F)c2)c1>>Nc1ccc2c(ccn2Cc2cccc(OC(F)(F)F)c2)c1,[Pt],CCOC(C)=O,,,,test
US20070167436A1,CCOC(=O)C1CCC(=O)CC1.Nc1ccccc1F>>CCOC(=O)C1CCCC(Nc2ccccc2F)C1,,C1CCOC1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05436247,COC(=O)CC#N.COc1ccc(C(=O)c2cc(OC)c(OC)cc2N)cc1OC>>COC(=O)Cc1nc(-c2ccc(OC)c(OC)c2)c2cc(OC)c(OC)cc2n1,,O,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20020065278A1,C1CCNCC1.O=Cc1ccc(O)cc1>>Cc1cc(N2CCCCC2)ccc1O,,CC(=O)O,ClCCCl,O=C([O-])O.[Na+],,test
US03984569,Fc1ccccc1CCl.N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(=O)O>>N[C@@H](CCC(=O)N[C@@H](CSCc1ccccc1F)C(=O)NCC(=O)O)C(=O)O,,CO,,CCN(CC)CC,Cl,test
US20050080096A1,COC(=O)[C@H](C)N.O=C(Cl)CCl>>COC(=O)[C@H](C)NC(=O)CCl,,ClCCl,,CCN(CC)CC,Cl,test
US20150126449A1,Cl.Cn1cc(-c2cccc3nn4c(C5CCN(C(=O)OC(C)(C)C)CC5)cc(=O)[nH]c4c23)cn1>>Cl.Cn1cc(-c2cccc3nn4c(C5CCNCC5)cc(=O)[nH]c4c23)cn1,,C1COCCO1,,,,test
US20150065468A1,COc1ccc(CCl)cc1.Cc1n[nH]c2ncc(Br)cc12>>COc1ccc(Cn2nc(C)c3cc(Br)cnc32)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20100137417A1,COC(=O)CCNC(=O)c1ccc(C(Oc2ccc(-c3ccc(C(F)(F)F)cc3)c(C)c2)C(C)(C)C)s1>>Cc1cc(OC(c2ccc(C(=O)NCCC(=O)O)s2)C(C)(C)C)ccc1-c1ccc(C(F)(F)F)cc1,,CO,,Cl,[Na+].[OH-],test
US05739330,BrBr.CC(=O)OC(C)=O.Cc1ccc(N)cc1C>>CC(=O)Nc1cc(C)c(C)cc1Br,,CC(=O)O,O,OO,,test
US03932465,COc1ccccc1.O=C(Cc1ccccc1)NC1C(=O)N2C(C(=O)O)C(CO)=CS[C@H]12>>COc1ccc(CC2=CS[C@@H]3C(NC(=O)Cc4ccccc4)C(=O)N3C2C(=O)O)cc1,,C1COCCO1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04959378,O=[N+]([O-])c1ccncc1Nc1cccc(O)c1>>Nc1ccncc1Nc1cccc(O)c1,,CCO,,,,test
US20100087427A1,COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2N)C(C)C)ccc1OC.O=S(=O)(Cl)Cc1ccccc1Cl>>COCCCOc1cc(C(=O)N(C[C@@H]2CNC[C@H]2NS(=O)(=O)Cc2ccccc2Cl)C(C)C)ccc1OC,,O,,CC#N,CC#N,test
US06150412,COc1cc([N+](=O)[O-])c(CC(=O)O)c([N+](=O)[O-])c1O>>O=C(O)Cc1c([N+](=O)[O-])cc(O)c(O)c1[N+](=O)[O-],,ClCCl,,BrB(Br)Br,,test
US20100234344A1,Clc1cnc(Cl)c(Br)c1.OCc1ccccc1>>Clc1cnc(OCc2ccccc2)c(Br)c1,,CCCCCC,CN(C)C=O,[H][H],[H-].[Na+],test
US20120082702A1,C1CNCCN1.NC(=O)c1ccc(Cl)nc1Nc1ccc(C(=O)N2CCOCC2)cc1>>NC(=O)c1ccc(N2CCNCC2)nc1Nc1ccc(C(=O)N2CCOCC2)cc1,,CN1CCCC1=O,ClCCl,,,test
US20160184318A1,Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)N2CCC(NC(=O)OC(C)(C)C)CC2)n1>>Cc1nnn(Cc2cc(Cl)ccc2/C=C/C(=O)N2CCC(N)CC2)n1,,ClCCl,,C1COCCO1,Cl,test
US20130188270A1,CCCCC(CC)Cn1c2ccccc2c2ccc3ccccc3c21.Cc1cc(C)c(C(=O)Cl)c(C)c1.O=C(Cl)c1ccccc1F>>CCCCC(CC)Cn1c2ccc(C(=O)c3ccccc3F)cc2c2cc(C(=O)c3c(C)cc(C)cc3C)c3ccccc3c21,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US04343808,N#CCCl.O=[N+]([O-])c1cccc(O)c1>>N#CCOc1cccc([N+](=O)[O-])c1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20030166697A1,O=C(O)c1ccc(CF)cc1.O=S(Cl)Cl>>O=C(Cl)c1ccc(CF)cc1,,c1ccccc1,,CN(C)C=O,,test
US20060281768A1,CC(C)c1ccc(N)cc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)c1ccc(NC(=O)Oc2ccc([N+](=O)[O-])cc2)cc1,,ClCCl,c1ccncc1,,,test
US20160159783A1,C[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1nc2cc(Cl)cc(Br)c2o1.Cc1ccc(B2OC(C)(C)C(C)(C)O2)o1>>Cc1ccc(-c2cc(Cl)cc3nc(N4CCN(C(=O)OC(C)(C)C)C[C@@H]4C)oc23)o1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,,test
US20120077810A1,CC(=O)Cl.CC(C)(C)OC(=O)NC1(c2ccc(-c3nc4nc(N)nn4cc3-c3ccccc3)cc2)CCC1>>CC(=O)Nc1nc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)cn2n1,CN(C)c1ccncc1,C1COCCO1,ClCCl,,,test
US20010023257A1,CC(C)(C)OC(=O)NC1CC2CC1C1C=CCC21.CC(C)(C)OC(=O)NC1CC2CC1C1CC=CC21>>CC(C)(C)OC(=O)NC1CC2CC1C1CC(O)CC21,,Cc1ccccc1,,,,test
US20050208582A1,N#Cc1cc(CO)c(Cl)s1>>N#Cc1cc(C=O)c(Cl)s1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US06329370B1,COc1ccc2c(Cc3c(Cl)cncc3Cl)nnc(Cl)c2c1.O=C1CCCN1>>COc1ccc2c(c1)C(N1CCCC1=O)NN=C2Cc1c(Cl)cncc1Cl,,CN(C)C=O,,O,[H-].[Na+],test
US20060122399A1,OCc1nc2ncccn2n1>>O=Cc1nc2ncccn2n1,,CO,,,,test
US05071999,C=CCN(CC=O)C(=O)OCC.O=C(O)C1CCCCN1>>CCOC(=O)N1CC2CC3CCCCN3C2C1,,Cc1ccccc1,,,,test
US04692442,COC(=O)C(=O)N1C(=O)[C@H](OC(=O)COc2ccccc2)[C@H]1SC(C)=O>>CC(=O)S[C@H]1NC(=O)[C@@H]1OC(=O)COc1ccccc1,,CO,ClCCl,,,test
US05684034,BrCc1ccccc1.Cc1c(CC(N)=O)c2cc(O)ccc2n1Cc1ccccc1>>Cc1c(CC(N)=O)c2cc(OCc3ccccc3)ccc2n1Cc1ccccc1,,CS(C)=O,O,[H-].[Na+],,test
US04066645,CI.Cc1cc2[nH]c(=O)c3cnccc3n2n1>>Cc1cc2n(C)c(=O)c3cnccc3n2n1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20110021522A1,CC1(C)OC(=O)CC(=O)O1.O=Cc1cccc(Br)c1O>>O=C(O)c1cc2cccc(Br)c2oc1=O,,O,,,,test
US20040209776A1,CCc1nsc(NC(=O)C(C)c2ccc(O)c([N+](=O)[O-])c2)c1Cl>>CCc1nsc(NC(=O)C(C)c2ccc(O)c(N)c2)c1Cl,[Pt],CN(C)C=O,,,,test
US20030096826A1,CN(C)c1ccc(S(=O)(=O)N[C@H](C=O)CC(=O)OC(C)(C)C)c(OCCc2cccc3ncccc23)c1>>CN(C)c1ccc(S(=O)(=O)N[C@H](C=O)CC(=O)O)c(OCCc2cccc3ncccc23)c1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20020072533A1,CCCCC[C@@H](C)C[C@H](CN=[N+]=[N-])CC(=O)OC(C)(C)C>>CCCCC[C@@H](C)C[C@H](CN)CC(=O)OC(C)(C)C,[Pd],C1CCOC1,,[H][H],,test
US20160122336A1,C[Si](C)(C)C(F)(F)F.O=C(c1ccc(Br)c(OC(F)F)c1)C(F)(F)F>>OC(c1ccc(Br)c(OC(F)F)c1)(C(F)(F)F)C(F)(F)F,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150336935A1,C1CCOC1.COc1cc(C)cc(OC[C@H]2C(C)=CC[C@H]3C(C)(C)CCC[C@]23C)c1>>COc1cc(C)cc(OC[C@H]2C(C)C(O)C[C@H]3C(C)(C)CCC[C@]23C)c1,,C1CCOC1,,B,,test
US20140296313A1,CCOC(=O)/C=C1/CCOC1.N>>CCOC(=O)CC1(N)CCOC1,,C1COCCO1,CO,,,test
US20110306588A1,CC(C)(C)OC(=O)N1CCC(Oc2ncccc2N2CCOCC2)CC1.Cl>>Cl.c1cnc(OC2CCNCC2)c(N2CCOCC2)c1,,CO,,,,test
US04968790,CCCCCCCCCCCCCCCCOCC(CO)OC.O=P(Cl)(Cl)Oc1ccccc1>>CCCCCCCCCCCCCCCCOCC(COP(=O)(Cl)Oc1ccccc1)OC,,CCN(CC)CC,,ClCCl,,test
US20020188122A1,[N-]=[N+]=NCCCn1cnc(-c2ccc(F)cc2)c1-c1ccncc1>>NCCCn1cnc(-c2ccc(F)cc2)c1-c1ccncc1,,C1CCOC1,,CCOC(C)=O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050143443A1,CCOC(=O)c1cc(C(=O)CCC2CCCC2)c[nH]1>>CCOC(=O)c1cc(CCCC2CCCC2)c[nH]1,,O=C(O)C(F)(F)F,,CC[SiH](CC)CC,,test
US04260617,COc1ccc2c(c1)[C@]13CCN(CC4CC4)[C@H](C2)[C@]1(O)CCC(=O)C3.Cl>>COc1ccc2c(c1)[C@]13CCN[C@H](C2)[C@]1(O)CCC(=O)C3.Cl,,CCO,,Cl,,test
US04219657,CN(C)CCCl.Cl.O=C(O)Cc1ccc2c(c1)sc1ccc(Cl)cc12>>CN(C)CCOC(=O)Cc1ccc2c(c1)sc1ccc(Cl)cc12.Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160016927A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.O=[N+]([O-])c1cccc(Br)c1F>>CC1(C)OB(c2cccc([N+](=O)[O-])c2F)OC1(C)C,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20160184318A1,CCOC(=O)/C=C/c1ccc(C)cc1Cn1nnc(C)n1>>Cc1ccc(/C=C/C(=O)O)c(Cn2nnc(C)n2)c1,,C1CCOC1,,[Na+].[OH-],,test
US20030008882A1,COc1ccc(-c2ccc(CCC#N)cc2CC(C)C)cc1CC(C)C>>CC(C)Cc1cc(-c2ccc(CCC#N)cc2CC(C)C)ccc1O,,ClCCl,,BrB(Br)Br,O,test
US20110054168A1,Clc1nc(Cl)c2ncn(C3CCCCO3)c2n1.NCc1ccccc1>>Clc1nc(NCc2ccccc2)c2ncn(C3CCCCO3)c2n1,,CO,,O,,test
US05302516,C=O.O=C(O)CCCCNCc1ccc([N+](=O)[O-])cc1>>CN(CCCCC(=O)O)Cc1ccc([N+](=O)[O-])cc1,,O,,[BH3-]C#N.[Na+],,test
US06514964B1,NCc1ccccc1.O=C(O)Cc1ccccc1Br>>O=C(Cc1ccccc1Br)NCc1ccccc1,,ClCCl,,CCN(CC)CC,CCN=C=NCCCN(C)C,test
US20070155805A1,CCCCC(CCOc1ccc(CC(=O)OCC)cc1Cl)c1sc2cc(C(F)(F)F)ccc2c1C>>CCCCC(CCOc1ccc(CC(=O)O)cc1Cl)c1sc2cc(C(F)(F)F)ccc2c1C,,C1CCOC1,CO,[Na+].[OH-],,test
US20100267697A1,CCN(c1ccc(CN(C(=O)C2CCN(C(=O)OC(C)(C)C)CC2)c2ccc(F)cc2)cn1)C1CC1>>CCN(c1ccc(CN(C(=O)C2CCNCC2)c2ccc(F)cc2)cn1)C1CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100113502A1,CC1CCN(C(=O)c2ccc3[nH]c4c(c3c2)CN(C2CCOCC2)CC4)CC1.Cc1oncc1S(=O)(=O)Cl>>Cc1oncc1S(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCOCC1)CC2,,CN(C)C=O,,[H-].[Na+],,test
US06340687B1,C=CCN1CCCN(c2c(C)cccc2Cl)C1=S>>CNCCCNc1c(C)cccc1Cl,,CCO,ClCCl,CN,,test
US20130196974A1,CC(=O)NCCOc1cc(N2CCS(=O)(=O)c3ccccc3C2)nc2ccc(C)cc12>>Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)cc(OCCN)c2c1,,Cl,,,,test
US05175314,C1CCOC1.CC(C)O.CCOCC.[Li]CCCC>>CC12CC(CO1)C1CC1C2=O,,C1CCOC1,,CC(C)NC(C)C,,test
US20110319394A1,CCn1c(=O)n(-c2ccc(OCc3ccccc3)cc2)c2nccc(C(F)(F)F)c21>>CCn1c(=O)n(-c2ccc(O)cc2)c2nccc(C(F)(F)F)c21,[Pd],CCOC(C)=O,CO,,,test
US20100069352A1,C=O.COc1cc(N2CCc3nc(-c4ccc(Cl)cc4)sc3C2=O)ccc1OC1CNC1>>COc1cc(N2CCc3nc(-c4ccc(Cl)cc4)sc3C2=O)ccc1OC1CN(C)C1,,CO,O,CC(=O)O,[BH3-]C#N.[Na+],test
US20040127574A1,NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1cccc2ccccc12.O=C(Cl)C1CCCCC1>>O=C(NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1cccc2ccccc12)C1CCCCC1,,CCOC(C)=O,O,Cl,O=C([O-])O.[Na+],test
US05998433,C=CCN.O=Cc1ccoc1>>C=CCNCc1ccoc1,,CO,,[Na+].[OH-],,test
US20100080771A1,OCc1cc(Br)ccc1-c1ccccc1>>O=Cc1cc(Br)ccc1-c1ccccc1,,CCOCC,O,,,test
US20070207994A1,CC(C)OC(=O)Cl.Cn1nccc1-c1cc(N)ccc1OCCN1CCSCC1>>CC(C)OC(=O)Nc1ccc(OCCN2CCSCC2)c(-c2ccnn2C)c1,,CS(C)=O,,ClCCl,c1ccncc1,test
US20090306066A1,CN(C)C1CN(C(=O)OCc2ccccc2)CC1(C)C>>CN(C)C1CNCC1(C)C,[Pd],CO,,,,test
US20040082569A1,C1COCCN1.C=Cc1ccc(CCl)cc1>>C=Cc1ccc(CN2CCOCC2)cc1,,CO,,,,test
US20050014942A1,Cn1c(-c2ccccc2)cc2cccnc21.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>Cn1c(-c2ccccc2)c(C(=O)O)c2cccnc21,,CN(C)C=O,,O,,test
US20160060257A1,COc1ccc(F)cc1-c1ccnc2c1cc(C1(O)CCS(=O)(=O)CC1)n2S(=O)(=O)c1ccc(C)cc1>>COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCS(=O)(=O)CC3)cc12,,C1COCCO1,CCOC(C)=O,O,[Na+].[OH-],test
US05373015,CCc1cc2c(ccc(=O)n2Cc2ccc([N+](=O)[O-])cc2)c(CC)n1>>CCc1cc2c(ccc(=O)n2Cc2ccc(N)cc2)c(CC)n1,O=[Pt]=O,C1CCOC1,,,,test
US06432993B1,CC(C)(C)c1cc(OCc2ccccc2)c(C(C)(C)C)cc1O.CN(C(=O)OC(C)(C)C)c1cc(Cl)ccc1[N+](=O)[O-]>>CN(C(=O)OC(C)(C)C)c1cc(Oc2cc(C(C)(C)C)c(OCc3ccccc3)cc2C(C)(C)C)ccc1[N+](=O)[O-],,CN(C)C=O,,[H-].[Na+],,test
US20120165537A1,O=C(O)C(CCSSc1ccccn1)S(=O)(=O)O.O=C1CCC(=O)N1O>>O=C(ON1C(=O)CCC1=O)C(CCSSc1ccccn1)S(=O)(=O)O,,CC(=O)N(C)C,,CCN=C=NCCCN(C)C,,test
US20080064872A1,CCOC(=O)C(=CC=Cc1ccc(CC)cc1)N=P(c1ccccc1)(c1ccccc1)c1ccccc1.O=Cc1ccc(C(F)(F)F)cc1>>CCOC(=O)c1ccc(-c2ccc(CC)cc2)c(-c2ccc(C(F)(F)F)cc2)n1,,CC#N,,,,test
US20090269420A1,CCOC(=O)CBr.N#Cc1c[nH]cn1>>CCOC(=O)Cn1cnc(C#N)c1,,CCO,,C,C[O-].[Na+],test
US20060217372A1,CC(C)OCCCN.NC(=O)c1cnc(Oc2ccc(C=O)cc2F)cn1>>CC(C)OCCCNCc1ccc(Oc2cnc(C(N)=O)cn2)c(F)c1,,CO,,[BH4-].[Na+],,test
US20060293340A1,CNc1ccc(C)c(Nc2nccc(-c3ccc(Cl)nc3)n2)c1.O=C(O)c1cccc(C(F)(F)F)c1>>Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1Nc1nccc(-c2ccc(Cl)nc2)n1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20140162971A1,CO.O=C(O)c1cc(Oc2ccc(F)cc2F)c(Br)cc1[N+](=O)[O-]>>COC(=O)c1cc(Oc2ccc(F)cc2F)c(Br)cc1[N+](=O)[O-],CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20160002175A1,CCCN.Nc1nc(Cl)cc(Cl)n1>>CCCNc1cc(Cl)nc(N)n1,,CCO,,,,test
US20030109574A1,COS(=O)(=O)OC.Oc1ccc(C(F)(F)F)cc1>>COc1ccc(C(F)(F)F)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05250521,CCc1nc2c(C)cc(C)nn2c1Cc1ccc(OC(C(=O)OC)c2cccc(Cl)c2)cc1>>CCc1nc2c(C)cc(C)nn2c1Cc1ccc(OC(C(=O)O)c2cccc(Cl)c2)cc1,,CO,,Cl,[Na+].[OH-],test
US20080214563A1,CN1CCC(N)CC1.C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(F)c4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F>>C[C@@H](Oc1cc(-n2cnc3cc(-c4ccnc(NC5CCN(C)CC5)c4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F,,ClCCl,,CCO,,test
US06005116,CC(C)(C)OC(=O)NCCOc1cc(-c2ccc(N)cc2)on1.O=C(Cl)c1ccccc1>>CC(C)(C)OC(=O)NCCOc1cc(-c2ccc(NC(=O)c3ccccc3)cc2)on1,,C1CCOC1,,CCN(CC)CC,,test
US20080300287A1,C=CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C>>C=CCCNC(=O)OC(C)(C)C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060111375A1,CCOC(=O)C(C)P(=O)(OCC)OCC.COc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)c(C=O)c1>>CCOC(=O)/C(C)=C/c1cc(OC)ccc1Oc1ccnc2cc(OC)c(OC)cc12,,C1CCOC1,,O,[H-].[Na+],test
US20110294776A1,CCOC1(O[Si](C)(C)C)CC1.Nc1ncnn2c(C3CCNC3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12>>Nc1ncnn2c(C3CCN(C4CC4)C3)cc(-c3ccc4cn(Cc5ccccc5)nc4c3)c12,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20050009841A1,CC(C)(C)OC(=O)N1C2CCC1CN(C(=O)C(F)(F)F)C2.[NH4+].[OH-]>>CC(C)(C)OC(=O)N1C2CCC1CNC2.[NH4+].[OH-],,CO,,,,test
US05399574,O=C1N[C@@H](Cc2ccc3[nH]cc(Sc4ccccc4)c3c2)CO1>>O=C1N[C@@H](Cc2ccc3[nH]ccc3c2)CO1,[Ni],CC(C)O,,,,test
US05550233,CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(O)(CC(=O)OCc4ccccc4)C(OC)C3)C(C)C(O[Si](C)(C)C(C)(C)C)CC1=O)C(C)CC2OC>>CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(O)(CC(=O)OCc4ccccc4)C(OC)C3)C(C)C(O)CC1=O)C(C)CC2OC,,CC#N,,,,test
US20050215574A1,COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC1CCCN(C(=O)COC(C)=O)C1>>COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC1CCCN(C(=O)CO)C1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US03974195,O=C(O)CCCCCCBr.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>O=C(O)CCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-],,CC#N,,,,test
US20140221421A1,COc1ccc2[nH]cc(CC(=O)NC(Cc3cc(F)cc(F)c3)c3cnc(-c4ccc(Cl)cc4)o3)c2n1>>O=C(Cc1c[nH]c2ccc(O)nc12)NC(Cc1cc(F)cc(F)c1)c1cnc(-c2ccc(Cl)cc2)o1,,CC(=O)O,,,,test
US20060257987A1,CC(CCO)Oc1cc2ccccc2cc1C(=O)c1ccccc1.CS(=O)(=O)Cl>>CC(CCOS(C)(=O)=O)Oc1cc2ccccc2cc1C(=O)c1ccccc1,,ClCCl,,,,test
US20090124612A1,C#C[Si](CC)(CC)CC.CC(C)(C)OC(=O)NCc1nnc2ccc(Cl)nn12>>CC[Si](C#Cc1ccc2nnc(CNC(=O)OC(C)(C)C)n2n1)(CC)CC,I[Cu]I,CC#N,,CCN(CC)CC,,test
US20030186973A1,CSc1ncc2c(n1)N(C1CCCC1)S(=O)(=O)C=C2.O=S(=O)(c1ccccc1)N1OC1c1ccccc1>>CS(=O)c1ncc2c(n1)N(C1CCCC1)S(=O)(=O)C=C2,,CO,ClCCl,,,test
US05424329,CCOCCl.COc1ccc2[nH]c(C(N)=O)c(OC(C)C)c2c1>>CCOCn1c(C(N)=O)c(OC(C)C)c2cc(OC)ccc21,,CCCCCC,CN(C)C=O,[H-].[Na+],,test
US20110183985A1,Cc1nc2c(Br)c(C(C)N=[N+]=[N-])ccc2s1.OB(O)c1cccc(F)c1>>Cc1nc2c(-c3cccc(F)c3)c(C(C)N=[N+]=[N-])ccc2s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,O,O=C([O-])[O-].[Na+].[Na+],test
US20100197697A1,C1CCNCC1.CC(Cl)OC(=O)Cl.CCN(C(C)C)C(C)C.C[C@@H](O)[C@H]1CCN(Cc2ccccc2)C[C@@H]1c1ccc(Cl)cc1.C[C@H](Oc1ccc(Cl)c(Cl)c1)[C@H]1CCN(C(=O)C2CCN(c3ccc(C#N)cn3)CC2)C[C@@H]1c1ccc(Cl)cc1.Cc1ccc(O)nc1>>Cc1ccc(O[C@@H](C)[C@H]2CCN(C(=O)C3CCN(c4ccc(C#N)cn4)CC3)C[C@@H]2c2ccc(Cl)cc2)nc1.N#Cc1ccc(N2CCC(C(=O)O)CC2)nc1,,CO,,,,test
US20150353560A1,CC(C)(C)OC(=O)Nc1cncc(F)c1.II>>CC(C)(C)OC(=O)Nc1cncc(F)c1I,,C1CCOC1,,CN(C)CCN(C)C,[Li]CCCC,test
US05854234,CCOC(=O)C(CC(CC1CCCCC(OC)=N1)OC)N=C(c1ccccc1)c1ccccc1.Cl.[Cl-].[NH4+]>>CCOC(=O)C(N)CC(CC1C=CC=CC(=N)N1)OC.Cl.Cl,,CO,,,,test
US04962115,O=[N+]([O-])c1cc(F)ccc1F.OC1CCC(O)CC1>>O=[N+]([O-])c1cc(F)ccc1OC1CCC(O)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20090318445A1,Nc1cccc2cccc(N)c12.O=C(O)[C@@H]1CCCN1C(=O)OCc1ccccc1>>O=C(OCc1ccccc1)N1CCCC1C1=Nc2cccc3cccc(c23)N1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100160258A1,CC(C)(C)C1CCC(Oc2ccc3cc([C@]4(C)COC(=O)N4)ccc3c2)CC1.CI>>CN1C(=O)OC[C@@]1(C)c1ccc2cc(OC3CCC(C(C)(C)C)CC3)ccc2c1,,C1CCOC1,CN(C)C=O,[H-].[Na+],,test
US20060148858A1,CCC(CC)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCO.COC(=O)Cc1ccccc1O>>CCC(CC)c1nn(-c2ccc(C(F)(F)F)cn2)cc1CCCOc1ccccc1CC(=O)O,,C1CCOC1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US20090054483A1,Cc1cccc(B(O)O)c1.N#Cc1cc(Cl)c2ccc(Cl)cc2n1>>Cc1cccc(-c2cc(C#N)nc3cc(Cl)ccc23)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,[Cs+].[F-],,test
US04977162,ClCc1cccc(OCc2ccc3ccccc3n2)c1.N#Cc1cc(=O)c2ccc(O)cc2o1>>N#Cc1cc(=O)c2ccc(OCc3cccc(OCc4ccc5ccccc5n4)c3)cc2o1,,CS(C)=O,,[Na+].[OH-],,test
US20110081365A1,ClCCl.Nc1nc2cc([N+](=O)[O-])ccc2c2cccnc12>>Nc1ccc2c(c1)nc(N)c1nc(Cl)ccc12,[Ni],CCO,,,,test
US06362177B1,COc1ncc(C=O)c(OC)n1.Nc1ccc(C(F)(F)F)cc1C(=O)NCC(=O)N[C@@H]1CCNC1>>COc1ncc(CN2CC[C@@H](NC(=O)CNC(=O)c3cc(C(F)(F)F)ccc3N)C2)c(OC)n1,,C1CCOC1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090149425A1,C#CCO.CCOC(=O)c1csc(Cl)n1>>C#CCOc1nc(C(=O)OCC)cs1,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20090118292A1,N#Cc1cccc(C(=O)CBr)c1.Nc1ccc(Cl)nn1>>N#Cc1cccc(-c2cn3nc(Cl)ccc3n2)c1,,CCO,,,,test
US20050215576A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.COC(=O)CP(=O)(OC)OC>>COC(=O)CC1CCN(C(=O)OC(C)(C)C)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20150126449A1,CC(C)(C)OC(=O)N1CCC(c2cc(=O)[nH]c3c4c(C(=O)O)cccc4nn23)CC1.Cl>>Cl.O=C(O)c1cccc2nn3c(C4CCNCC4)cc(=O)[nH]c3c12,,C1COCCO1,,,,test
US05077409,CCCCCCCCCCCCCCOc1ccc(CN(C(C)=O)c2cccc(CBr)c2)cc1.Cc1cncs1>>CCCCCCCCCCCCCCOc1ccc(CN(C(C)=O)c2cccc(C[n+]3csc(C)c3)c2)cc1.[Br-],,CCOCC,Cc1ccccc1,,,test
US20020091242A1,CCCCCCCCCCCCCCN(CCCCCCCCCCCCCC)C(=O)CCCOC1OCC(CN)O1.O=C(O)CN(CCCN(CCCNC(=O)C(F)(F)F)CCCNC(=O)C(F)(F)F)C(=O)C(F)(F)F>>CCCCCCCCCCCCCCN(CCCCCCCCCCCCCC)C(=O)CCCOC1OCC(CNC(=O)CN(CCCN(CCCNC(=O)C(F)(F)F)CCCNC(=O)C(F)(F)F)C(=O)C(F)(F)F)O1,,ClCCl,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20050137243A1,ClCCN1CCCC1.O=[N+]([O-])c1cccc2[nH]ncc12>>O=[N+]([O-])c1cccc2c1cnn2CCN1CCCC1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US04652651,COc1ccc(CN2C(=O)[C@@H](NC(=O)OC(C)(C)C)[C@H]2C=O)c(OC)c1.NC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>COc1ccc(CN2C(=O)[C@H](NC(=O)OC(C)(C)C)[C@@H]2/C=C/C(N)=O)c(OC)c1,,ClCCl,,,,test
US20100041628A1,N#CC(C(N)=O)c1ccc(Br)cc1[N+](=O)[O-]>>NC(=O)c1c(N)[nH]c2cc(Br)ccc12,[Zn],CC(=O)O,Cc1ccccc1,,,test
US20110053916A1,CC(C)(C)c1cc(N)n[nH]1.Clc1cnc(Br)nc1Br>>CC(C)(C)c1cc(Nc2nc(Br)ncc2Cl)n[nH]1,,CCO,,CCOC(C)=O,O,test
US06562839B1,CCOC(=O)c1cc2cc(-n3cnc(CO)c3)c([N+](=O)[O-])cc2nc1OCC.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)OCc1cn(-c2cc3cc(C(=O)O)c(=O)[nH]c3cc2[N+](=O)[O-])cn1,,ClCCl,,CC(C)OC(C)C,,test
US20030109523A1,COC(=O)CC1CCc2cc(OCCCNc3ncccn3)ccc2C1>>O=C(O)CC1CCc2cc(OCCCNc3ncccn3)ccc2C1,,C1COCCO1,O,[Li]O,,test
US04707488,[N-]=[N+]=NCCCc1cc(F)cc(F)c1>>NCCCc1cc(F)cc(F)c1,,CO,,,,test
US07880004B2,CCOC(=O)c1ccc(O)c(F)c1.NC(=O)c1cc(Cl)ccn1>>NC(=O)c1cc(Oc2ccc(C(=O)O)cc2F)ccn1,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20040087552A1,CCn1nc(C)c(OC)c1C1CCN(C(=O)OC(C)(C)C)CC1>>CCn1nc(C)c(OC)c1C1CCNCC1,,ClCCl,O=C(O)C(F)(F)F,,,test
US04294960,BrC1CCCCC1.CCOC(=O)C(=NO)C(C)=O>>CCOC(=O)C(=NOC1CCCCC1)C(C)=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150232481A1,C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(CN)nn23)CC1.C=CCc1ccccc1C(=O)O>>C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(CNC(=O)c4ccccc4CC=C)nn23)CC1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US05278191,NC(=O)CI.NCc1ccccc1-c1cccc(Cl)c1>>NC(=O)CNCc1ccccc1-c1cccc(Cl)c1,,CCO,,O=C([O-])O.[Na+],,test
US20120232081A1,COC(=O)c1c(Cc2cccc(F)c2C)c(-c2ccccc2)n2ccc(Br)cc12>>Cc1c(F)cccc1Cc1c(C(=O)O)c2cc(Br)ccn2c1-c1ccccc1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20150025093A1,CN(C)C1CCC(N)CC1.Clc1nc(Cl)c2c3c(sc2n1)CCC3>>CN(C)C1CCC(Nc2nc(Cl)nc3sc4c(c23)CCC4)CC1,,CCOC(C)=O,CN(C)C=O,Cl,O=C([O-])[O-].[K+].[K+],test
US20090227570A1,CC(C)(C)OC(=O)NC1CCNCC1.CSCCCl>>CSCCN1CCC(NC(=O)OC(C)(C)C)CC1,,CO,,CCN(CC)CC,,test
US06544976B1,CC(C)N=C=NC(C)C.CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2.CN(C)c1ccccn1.ClCCl.O=C(O)C1CCN1.OCCCc1cccnc1>>Cc1cc(C(=O)N2CC[C@H]2C(=O)OCCCc2cccnc2)nn1C,,ClCCl,,,,test
US20130196960A1,Cc1[nH]c2sccc2c1C(=O)c1cccc(Cl)c1Cl.ClCCN1CCOCC1>>Cc1c(C(=O)c2cccc(Cl)c2Cl)c2ccsc2n1CCN1CCOCC1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20020147343A1,C#C[Mg]Cl.Cc1cn(C(=O)OC(C)(C)C)c(C=O)c1C>>C#CC(O)c1c(C)c(C)cn1C(=O)OC(C)(C)C,,C1CCOC1,,,,test
US20150361100A1,CC(c1cc2ccccn2c1-c1ccccn1)n1nc(-c2cnc(NC(=O)OC(C)(C)C)s2)c2c(N)ncnc21>>CC(c1cc2ccccn2c1-c1ccccn1)n1nc(-c2cnc(N)s2)c2c(N)ncnc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100234473A1,C=O.CC(=O)c1ccccc1.CC(C)NC(C)C>>CC(C)N(CCC(O)c1ccccc1)C(C)C,,CO,O,Cl,,test
US20070244087A1,CC(C)(C)OC(=O)NC1CSCCNC1=O.Clc1cc(CBr)cc(Cl)n1>>CC(C)(C)OC(=O)NC1CSCCN(Cc2cc(Cl)nc(Cl)c2)C1=O,,CCOC(C)=O,O,CN(C)C=O,[H-].[Na+],test
US20100063098A1,COC(=O)c1ccc(=O)n(-c2c(F)cccc2F)c1>>O=C(O)c1ccc(=O)n(-c2c(F)cccc2F)c1,,C1CCOC1,CCO,[Na+].[OH-],,test
US20060094588A1,BrCc1ccccc1.C/C(=N\c1c(-c2ccccc2)cccc1-c1ccccc1)c1nc2ccccc2[nH]1>>C/C(=N\c1c(-c2ccccc2)cccc1-c1ccccc1)c1nc2ccccc2n1Cc1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20140155437A1,CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2C(=O)c2ccncc2)cc1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2C(=O)c2cc[n+]([O-])cc2)cc1,,ClCCl,,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20040138065A1,FCCBr.N#CC(C#N)Cc1ccc(Cl)cc1>>N#CC(C#N)(CCF)Cc1ccc(Cl)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20100249085A1,CC(C)[Si](Cl)(C(C)C)C(C)C.CCOC(=O)c1ccc(O)cc1>>CCOC(=O)c1ccc(O[Si](C(C)C)(C(C)C)C(C)C)cc1,,CN(C)C=O,,O,c1c[nH]cn1,test
US06235680B1,COCC(=O)Nc1ccc(S(N)(=O)=O)cc1.COc1ccccc1C(=O)Cl>>COCC(=O)Nc1ccc(S(=O)(=O)NC(=O)c2ccccc2OC)cc1,CN(C)c1ccncc1,CC#N,,CCN(CC)CC,O,test
US20160075710A1,CC(=O)c1cn[nH]c(=O)c1-c1ccccc1.ClCCN1CCOCC1>>CC(=O)c1cnn(CCN2CCOCC2)c(=O)c1-c1ccccc1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20140171435A1,COc1ccc(CCl)cc1.Oc1ccc(F)c(Br)c1>>COc1ccc(COc2ccc(F)c(Br)c2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04766115,CO.N#CN1Cc2ccccc2-c2ccccc2C1>>COC(=N)N1Cc2ccccc2-c2ccccc2C1,,CO,,[Na],C[O-].[Na+],test
US20020026060A1,CCCCCC(C(=O)OCC)c1ccc(NC(=O)C=C(C)C)cc1>>CCCCCC(C(=O)OCC)c1ccc2c(c1)C(C)(C)CC(=O)N2,,ClCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US06596758B1,CCO.O=C(O)C1=Cc2ccccc2OCC1>>CCOC(=O)C1=Cc2ccccc2OCC1,,O=S(=O)(O)O,,,,test
US04312874,C1CCOC1.Cc1ccncc1.[Cl-].[Cl-].[Mn+2]>>O=[Mn](Cl)(Cl)Cc1ccncc1,,CCCCCC,,[Li]CCCC,,test
US20070078120A1,COC(=O)c1cccc(S(N)(=O)=O)c1>>NS(=O)(=O)c1cccc(C(=O)O)c1,,CO,,[Li+].[OH-],,test
US20060264415A1,CCOC(=O)C=CC=Cc1ccn(S(=O)(=O)c2ccc(OC)c(OC)c2)c1>>CCOC(=O)CCCCc1ccn(S(=O)(=O)c2ccc(OC)c(OC)c2)c1,[Pd],CCOC(C)=O,CO,,,test
US20100174065A1,CC(C)(C)OC(=O)CBr.CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCNCC4)no2)cc1Cl>>CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCN(CC(=O)OC(C)(C)C)CC4)no2)cc1Cl,,ClCCl,,Cl,O=C([O-])[O-].[K+].[K+],test
US20160168100A1,Cc1ccc(OCc2ccccc2)cc1C=O.O=C(O)CC(=O)O>>Cc1ccc(OCc2ccccc2)cc1/C=C/C(=O)O,,c1ccncc1,,C1CCNCC1,,test
US06117841,CC(C)CC=O.CC(C)C[C@H](N)C(=O)O>>CCC(C)CN[C@@H](CC(C)C)C(=O)O,[Pd],CCO,,[Na+].[OH-],,test
US20100016343A1,COc1ccccc1B(O)O.O=C(NCCCCN1CCCCC1)Nc1ccc(Br)nc1>>COc1ccccc1-c1ccc(NC(=O)NCCCCN2CCCCC2)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC#N,,O=C([O-])[O-].[Na+].[Na+],,test
US20040077681A1,N#Cc1cc(-c2ccccc2)ncc1Cl.NN>>Nc1n[nH]c2cnc(-c3ccccc3)cc12,,c1ccncc1,,O,,test
US20080214546A1,COCCO.Cc1ccc(Cl)cc1CNC(=O)c1cc(NC(=O)C(F)(F)F)no1>>COCCN(C(=O)C(F)(F)F)c1cc(C(=O)NCc2cc(Cl)ccc2C)on1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130143862A1,CC(C)(C)OC(=O)N(CC1(c2ncccc2F)CCC1)c1ccc(-c2ncc(CN)s2)nn1.O=C(O)CO>>CC(C)(C)OC(=O)N(CC1(c2ncccc2F)CCC1)c1ccc(-c2ncc(CNC(=O)CO)s2)nn1,,CCOC(C)=O,CN(C)C=O,ClCCCl,On1nnc2ccccc21,test
US20090062251A1,CN(CCCC(=O)O)C(=O)c1ccc2c(c1)c1c(n2C)CC[C@@H](C2CCOCC2)C1.COCCN>>COCCNC(=O)CCCN(C)C(=O)c1ccc2c(c1)c1c(n2C)CC[C@@H](C2CCOCC2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06248755B1,COc1ccc(COC(=O)[C@@H](C2CCCCC2)N2C[C@H](c3ccccc3)[C@@H](C=O)C2)cc1.c1ccc(Cc2cnn(C3CCNCC3)n2)cc1>>O=C(O)[C@@H](C1CCCCC1)N1C[C@H](c2ccccc2)[C@@H](CN2CCC(n3ncc(Cc4ccccc4)n3)CC2)C1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20120289526A1,CC[C@H](C(=O)Nc1ccc(Oc2cccc(C(C)C)c2)nc1)N(C(=O)[O-])C(C)(C)C>>CC[C@@H](N)C(=O)Nc1ccc(Oc2cccc(C(C)C)c2)nc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050014786A1,O=S(=O)(N[C@H]1Cc2cc(Br)ccc2N(Cc2ccccc2)C1)c1ccccc1.OB(O)c1ccccc1>>O=S(=O)(NC1Cc2cc(-c3ccccc3)ccc2N(Cc2ccccc2)C1)c1ccccc1,,C1CCOC1,CO,O=C([O-])[O-].[K+].[K+],,test
US20060235050A1,CC(C)(C)OC(=O)NCC#CCN.O=C(O)CCCCC(c1ccc(F)cc1)c1ccc(F)cc1>>CC(C)(C)OC(=O)NCC#CCNC(=O)CCCCC(c1ccc(F)cc1)c1ccc(F)cc1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20150284391A1,CO.COc1ccc2nc(Cl)c(F)c(Cl)c2c1>>COc1ccc2nc(OC)c(F)c(Cl)c2c1,,CO,,C[O-].[Na+],,test
US20160200724A1,CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3c(c2)CN(C(=O)OC(C)(C)C)[C@H]3C(C)C)cc1>>CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3c(c2)CN[C@H]3C(C)C)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050020846A1,COC(=O)CCl.O=CC1CC1>>COC(=O)C1OC1C1CC1,,CO,O,CC(=O)O,C[O-].[Na+],test
US20070179165A1,CCOC(=O)c1c(C#N)ccn1-c1c(C)cc(C)cc1C.NN>>Cc1cc(C)c(-n2ccc3c(N)n[nH]c(=O)c32)c(C)c1,,O,,CCO,,test
US20070037802A1,CI.Cc1ccc(S(=O)(=O)OCCOc2ccc3[nH]nc(S(=O)(=O)c4cccc5ccccc45)c3c2)cc1>>Cc1ccc(S(=O)(=O)OCCOc2ccc3c(c2)c(S(=O)(=O)c2cccc4ccccc24)nn3C)cc1,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04126689,CCOC(=O)N1CCC(=Nc2c(Cl)cccc2Cl)CC1>>CCOC(=O)N1CCC(Nc2c(Cl)cccc2Cl)CC1,,CC(C)O,,CO,[BH4-].[Na+],test
US20160159773A1,CC1(O)CCCNC1.O=C(O)c1ccc(Br)nc1>>CC1(O)CCCN(C(=O)c2ccc(Br)nc2)C1,,CCOC(C)=O,,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US20080058423A1,CNC(C)c1cccc2cc(N(C)C)ccc12.O=C(Cl)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1>>CC(c1cccc2cc(N(C)C)ccc12)N(C)C(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1.Cl,,ClCCl,,,,test
US20040180892A1,CS(=O)(=O)Cl.Cc1cc(C)c(N2CCCC2)c(C)c1NS(=O)(=O)c1cc(Cl)cc(Cl)c1N>>Cc1cc(C)c(N2CCCC2)c(C)c1NS(=O)(=O)c1cc(Cl)cc(Cl)c1NS(C)(=O)=O,,CN(C)C=O,,[H-].[Na+],,test
US04302460,COc1ccc2c(=S)c(C)cn(C)c2c1>>Cc1cn(C)c2cc(O)ccc2c1=S,,CC(=O)O,,Br,O=C([O-])O.[Na+],test
US20110230476A1,CN.CS(=O)(=O)OCc1cc2nc(Cl)nc(N3CCOCC3)c2s1>>CNCc1cc2nc(Cl)nc(N3CCOCC3)c2s1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US06509359B1,CCC(C=O)CC.COC(=O)c1ccc(N2C(=O)CCC2(CO)CO)c(N)c1>>CCC(CC)N(C)c1cc(C(=O)OC)ccc1N1C(=O)CCC1(CO)CO,,ClCCl,,CC(=O)O,[BH3-]C#N.[Na+],test
US20030119840A1,O=[N+]([O-])c1cccc2cc(N3CCN4CCC3CC4)cnc12>>Nc1cccc2cc(N3CCN4CCC3CC4)cnc12,[Fe],CC(=O)O,O,,,test
US20140128424A1,CCOC(=O)c1c(C)nc2c(OCc3c(F)cccc3F)cc(C3CC3)cn12>>Cc1nc2c(OCc3c(F)cccc3F)cc(C3CC3)cn2c1C(=O)O,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20160096827A1,CC(C)(C)OC(=O)N1CC[C@H](Oc2ccc(B3OC(C)(C)C(C)(C)O3)cc2C#N)C(F)(F)C1.COc1cc(Nc2ncnc(Cl)n2)ccc1N1CCN(C2COC2)CC1>>COc1cc(Nc2ncnc(-c3ccc(O[C@H]4CCN(C(=O)OC(C)(C)C)CC4(F)F)c(C#N)c3)n2)ccc1N1CCN(C2COC2)CC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20140206681A1,COC(=O)[C@H]1CC[C@H](COC(C)=O)N(C(=O)OCc2ccccc2)C1>>COC(=O)[C@H]1CC[C@H](CO)N(C(=O)OCc2ccccc2)C1,,CO,,Cl,,test
US20150031690A1,CC(C)(C)[S@](=O)N[C@@](CC=O)(c1ccccc1F)C(F)F.C[Si](C)(C)C(F)(F)F>>CC(C)(C)[S@](=O)N[C@@](C[C@@H](O)C(F)(F)F)(c1ccccc1F)C(F)F,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120329785A1,CCN1CCN(c2ccc(N)cc2)CC1.COc1ccc(Cn2cc3c(n2)c(Cl)nc2ccc(OC)cc23)cc1>>CCN1CCN(c2ccc(Nc3nc4ccc(OC)cc4c4c[nH]nc34)cc2)CC1,C1COCCO1,CO,,Cl,,test
US20080113966A1,CC(C)(C)OC(=O)N[C@@H]1CC[C@@H](c2cccc(F)c2F)Cn2c(C(C)(C)O)cnc21>>CC(C)(O)c1cnc2n1C[C@H](c1cccc(F)c1F)CC[C@H]2N,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20090099161A1,CCOCc1nc2cnc3cc(/C=C/CCN4C(=O)c5ccccc5C4=O)ccc3c2n1CCCOC(C)C>>CCOCc1nc2cnc3cc(CCCCN4C(=O)c5ccccc5C4=O)ccc3c2n1CCCOC(C)C,[Pd],CCO,,,,test
US20010039281A1,COc1ccc(N2CCN(c3ccc(-n4cnn(C(C)C(C)OS(C)(=O)=O)c4=O)cc3)CC2)cc1>>COc1ccc(N2CCN(c3ccc(-n4cnn(C(C)C(C)O)c4=O)cc3)CC2)cc1,,C1CCOC1,CO,[K+].[OH-],,test
US20040127555A1,O=C(O)c1ccc(OCc2ccccc2)c(OCc2ccccc2)c1.O=S(Cl)Cl>>O=C(Cl)c1ccc(OCc2ccccc2)c(OCc2ccccc2)c1,c1ccncc1,,,,,test
US20150218112A1,C=O.CCC(=O)CCCCC[C@H](N)c1ncc(-c2cc3ccccc3nc2OC)o1.O=Cc1ccccc1>>CCC(=O)CCCCC[C@@H](c1ncc(-c2cc3ccccc3nc2OC)o1)N(C)Cc1ccccc1,,CC(Cl)Cl,ClCCl,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130158067A1,Fc1ccc2c(c1Br)CC=C2.O=C(OO)c1cccc(Cl)c1>>Fc1ccc2c(c1Br)CC1OC21,,ClCCl,,,,test
US20080167307A1,CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCN)cs1.Clc1ccc(Cl)nn1>>CC(C)(C)OC(=O)C(C)(C)Sc1nc(CCNc2ccc(Cl)nn2)cs1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,O,test
US20070225271A1,CC1(C)OC(C)(C)c2nc(Cl)ncc21.CCOc1cc(CN2CCC(N)CC2)ccc1OC>>CCOc1cc(CN2CCC(Nc3ncc4c(n3)C(C)(C)OC4(C)C)CC2)ccc1OC,,CN(C)C=O,,[H-].[Na+],,test
US20050215572A1,CC(C)(C)c1ccc(N)cc1.Clc1nc(CN2CCOCC2)nc2c1CCN(Cc1ccccc1)C2>>CC(C)(C)c1ccc(Nc2nc(CN3CCOCC3)nc3c2CCN(Cc2ccccc2)C3)cc1,,CC#N,,,,test
US20080255134A1,NCCOc1ccc(C2=NNC(=O)CC2)cc1Cl.c1ccc2c(c1)[nH]c1cccc(OC[C@@H]3CO3)c12>>O=C1CCC(c2ccc(OCCNC[C@H](O)COc3cccc4[nH]c5ccccc5c34)c(Cl)c2)=NN1,,CCO,,,,test
US20030119827A1,CC(C)CC(O)C(=O)NC1(C#N)CCN(Cc2ccccc2)C1.NCc1ccccc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CC(C)CC(OC(=O)NCc1ccccc1)C(=O)NC1(C#N)CCN(Cc2ccccc2)C1,CN(C)c1ccncc1,C1CCOC1,CCOC(C)=O,CN1CCOCC1,,test
US20120059028A1,COC(=O)C(OC(C)(C)C)c1c(C)nc2sc3c(c2c1Oc1ccccc1)CCCC3>>Cc1nc2sc3c(c2c(Oc2ccccc2)c1C(OC(C)(C)C)C(=O)O)CCCC3,,CO,,[Na+].[OH-],,test
US20060040918A1,NC1CC1.O=C(O)c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1>>O=C(NC1CC1)c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1,,ClCCl,,O=C(c1ncc[nH]1)c1ncc[nH]1,,test
US20030203852A1,COc1ccc(COC(=O)CBr)cc1.N[C@H](CS)C(=O)O>>N[C@@H](CSCC(=O)OCc1ccccc1)C(=O)O,,C1CCOC1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20150297586A1,ClCCCCn1nnc2ccccc21.c1ccc2nc(C3CCNCC3)cnc2c1>>c1ccc2nc(C3CCN(CCCCn4nnc5ccccc54)CC3)cnc2c1,,CC#N,,CCN(C(C)C)C(C)C,[I-].[K+],test
US20060235021A1,C=CCO.Clc1cc(-c2cccc(Br)c2)cnn1>>C=CCOc1cc(-c2cccc(Br)c2)cnn1,,C1CCOC1,CCOC(C)=O,[H-].[Na+],,test
US20040192742A1,O=C(Cl)c1ccccc1.O=C(NC1CNCC1O)C(CS(=O)(=O)Cc1ccccc1)NC(=O)N1CCOCC1>>O=C(NC1CN(C(=O)c2ccccc2)CC1O)C(CS(=O)(=O)Cc1ccccc1)NC(=O)N1CCOCC1,,C1COCCO1,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20160176868A1,NC(CC(=O)O)c1ccc(F)c(F)c1.O=S(Cl)Cl>>Cl.NC(CC(=O)O)c1ccc(F)c(F)c1,,CCCO,,,,test
US05998433,CN(C)Cc1cc2c(o1)CCN(C(=O)CCc1cccc(CCc3ccccc3)c1)C2.Cl>>CN(C)Cc1cc2c(o1)CCN(C(=O)CCc1cccc(CCc3ccccc3)c1)C2.Cl,,CO,,,,test
US20040106645A1,Nc1ccc(Cl)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>O=C(Nc1ccc(Cl)cc1)C(F)(F)F,,C1CCOC1,,CCN(CC)CC,,test
US20060228648A1,COS(=O)(=O)OC.CSc1ccccc1>>C[S+](C)c1ccccc1.O=S(=O)([O-])O,,CCOCC,,O,,test
US20030092676A1,CC(=O)C(=O)OCCBr.c1ccc2c(c1)CCCN2>>CCOC(=O)C(=O)CN1CCCc2ccccc21,,C1CCOC1,,,,test
US20030092676A1,C=CCN.ClCCl.O=C1CCCc2ccccc2N1>>C=CCNCc1cccc2cc[nH]c12,,ClCCCl,ClCCl,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20040157861A1,O=C(CCl)Nc1cccc(Cl)c1.Sc1nc(-c2cccnc2)n[nH]1>>O=C(CSc1nc(-c2cccnc2)n[nH]1)Nc1cccc(Cl)c1,,CN(C)C=O,,CCN(CC)CC,,test
US20020169188A1,CO/C=C/C1Cc2cc(-c3ccc(C#N)cc3)ccc2O1>>N#Cc1ccc(-c2ccc3c(c2)CC(CC=O)O3)cc1,,CC(C)=O,ClCCl,Cc1ccc(S(=O)(=O)O)cc1,O,test
US05744471,O=C1c2[nH]c3cc(Cl)ccc3c(=O)c2C(=O)N1Nc1ccc(F)cc1>>O=c1c2ccc(Cl)cc2[nH]c2c(=O)n(-c3ccc(F)cc3)nc(O)c12,,CO,,CS(=O)(=O)O,,test
US20030232875A1,O=C(NCC1(c2ccccc2)OCCO1)c1cc2sc(Cl)c(Cl)c2[nH]1>>O=C(CNC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1)c1ccccc1,,CC(C)=O,,Cl,,test
US20100016344A1,COC(=O)OC.O=C1CCCCC(c2ccccc2)C1>>COC(=O)C1CCCC(c2ccccc2)CC1=O,CO,,,[H-].[Na+],,test
US05273989,CC(C)(C)OC(=O)C=CCN.CC(C)(C)OC(=O)CCC[N+](=O)[O-]>>NCC1CC(CCC(=O)O)=NO1,,CC(C)=O,,,,test
US20090275578A1,COC(=O)c1ccccc1CBr.COc1ccc(CCCN)cc1>>COc1ccc(CCCN2Cc3ccccc3C2=O)cc1,,CCCCCC,Cc1ccccc1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20040138277A1,CCCc1cc(CC(C)(Oc2ccccc2)C(=O)OCC)ccc1O.Cc1ccc(S(=O)(=O)OCCc2nc(-c3cccc(-c4ccccc4)c3)oc2C)cc1>>CCCc1cc(CC(C)(Oc2ccccc2)C(=O)OCC)ccc1OCCc1nc(-c2cccc(-c3ccccc3)c2)oc1C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20050245529A1,CC1(O)CCNCC1.CS(=O)(=O)OC1CCN(c2ccc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)cc2)C1>>CC1(O)CCN(C2CCN(c3ccc(C#Cc4ccc(-c5ccc(Cl)cc5)cn4)cc3)C2)CC1,,CN(C)C=O,O,,,test
US20020025960A1,CCOC(=O)c1cn(C)c2cnc(CN3CCOCC3)cc2c1=O.NCc1ccc(Cl)cc1>>Cn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCOCC3)ncc21,,Cc1ccccc1,ClCCl,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20110082165A1,CS(=O)(=O)Cl.N#CC[C@@H]1CCCN1c1ccc(OCc2ccccc2)cc1.O>>CS(=O)(=O)OC[C@@H]1CCCN1c1ccc(OCc2ccccc2)cc1,,ClCCl,O,CCN(CC)CC,CCOC(C)=O,test
US20100317582A1,N=C(NO)c1cccc(C(F)(F)F)c1.O=C1CC(C(=O)O)C1>>O=C1CC(c2nc(-c3cccc(C(F)(F)F)c3)no2)C1,,CCOC(C)=O,,,,test
US20110118245A1,COCCOc1cc2ncnc(Sc3cccc(N)c3)c2cc1OC.Cn1nc(C(F)(F)F)cc1NC(=O)Oc1ccccc1>>COCCOc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(C(F)(F)F)nn4C)c3)c2cc1OC,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US05935999,CO/C=C(/C(=O)OC)c1ccccc1CON1C(=O)c2ccccc2C1=O>>CO/C=C(/C(=O)OC)c1ccccc1CON,,CCOCC,CO,NN,O,test
US04269774,NC(N)=S.O=C(c1ccccc1)c1cc(Cl)ccc1C(=O)C(Br)CN1C(=O)c2ccccc2C1=O>>Nc1nc(-c2ccc(Cl)cc2C(=O)c2ccccc2)c(CN2C(=O)c3ccccc3C2=O)s1,,CCO,O,,,test
US20150057271A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.O=C(O)C(F)(F)F.O=S(=O)(Nc1cncs1)c1ccc2c(c1)OCCN2c1ccc(C(F)(F)F)cc1Br>>O=C(O)C(F)(F)F.O=S(=O)(Nc1cncs1)c1ccc2c(c1)OCCN2c1ccc(C(F)(F)F)cc1C1=CCNCC1,,C1COCCO1,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US05550147,CC(=O)Cl.CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(O)cc2)cc1>>CC(=O)Oc1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(S(C)(=O)=O)cc2)cc1,,c1ccncc1,,Cl,O,test
US03962249,C[C@H]1NCCN(CCCc2ccccc2)[C@H]1C.O=C(Cl)c1ccco1>>C[C@H]1[C@@H](C)N(C(=O)c2ccco2)CCN1CCCc1ccccc1.Cl,,c1ccccc1,,,,test
US20100029633A1,CCOC(=O)c1cnc2cc(OCCOC)ccn12>>COCCOc1ccn2c(C(=O)O)cnc2c1,,C1CCOC1,CCO,Cl,[Li+].[OH-],test
US20060148861A1,CC1(C)C(C(=O)Cl)C1(C)C.CON>>CONC(=O)C1C(C)(C)C1(C)C,,ClCCl,,CCN(CC)CC,Cl,test
US20050171087A1,CC(C)C=O.N[C@@H]1CCCN2c3cc(Cl)ccc3Oc3ccccc3[C@H]12>>CC(C)CN[C@@H]1CCCN2c3cc(Cl)ccc3Oc3ccccc3[C@H]12,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US04472305,CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(N)=O.Cl>>CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](N)Cc1ccccc1)C(N)=O.Cl,,CCOC(C)=O,,,,test
US20110003820A1,CC1=NCCn2c(C)ccc21>>Cc1ccc2n1CCNC2C,,CO,,[BH4-].[Na+],,test
US20040224997A1,COS(=O)(=O)OC.O=C(O)C1CCOCC1>>COC(=O)C1CCOCC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120329649A1,Nc1ccccn1.O=Cc1ccc(CBr)c(Cl)c1>>O=Cc1ccc(CNc2ccccn2)c(Cl)c1,,CC(=O)N(C)C,O,O=C([O-])[O-].[K+].[K+],,test
US20100249187A1,ClCCN(CCCl)Cc1ccccc1>>ClCCN(CCCl)Cc1ccccc1,,O,,Cl,[Na],test
US04382939,CN(C)C=O.COc1cc2oc(=O)c3c(c2cc1[N+](=O)[O-])CCNC3>>COc1cc2oc(=O)c3c(c2cc1N)CCN(CC(C)=O)C3,[Ni],CN(C)C=O,,,,test
US05167949,N#Cc1nccnc1N.N=C(N)COc1ccccc1>>Nc1nc(COc2ccccc2)nc2nccnc12,,CCO,,,,test
US20050187236A1,C1COCCN1.CNC(=O)n1ccc2cc(Oc3ccnc(N(C(=O)Oc4ccccc4)C(=O)Oc4ccccc4)c3)ccc21>>CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)N4CCOCC4)c3)ccc21,,CN(C)C=O,,,,test
US20100056784A1,CC1(C)C2CC[C@]1(CS(=O)(=O)O)C(=O)C2.C[C@@H](c1ncncc1F)[C@](O)(Cn1cncn1)c1ccc(F)cc1F>>CC1(C)C2CC[C@]1(CS(=O)(=O)[O-])C(=O)C2.C[C@@H](c1ncncc1F)[C@](O)(Cn1cncn1)c1ccc(F)cc1F,,CO,,,,test
US20150210690A1,CC(C)(C)OC(=O)NC(C)(C)C(=O)O.CC(C)c1coc(C(=O)N[C@H](Cc2ccc(-c3cc(Cl)ccc3F)cc2)C[C@@H](N)C(=O)O)n1>>CC(C)c1coc(C(=O)N[C@H](Cc2ccc(-c3cc(Cl)ccc3F)cc2)C[C@@H](NC(=O)C(C)(C)N)C(=O)O)n1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130203752A1,BrBr.CCC(=O)c1cccc(C)c1>>Cc1cccc(C(=O)C(C)Br)c1,,ClCCl,,,,test
US20080081812A1,CCOC(=O)c1cc(-c2ccc(Cl)cc2)n(-c2ccc(Cl)cc2Cl)n1.ClCl>>CCOC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1Cl,,CC(=O)O,,,,test
US20040152730A1,C[C@H](N)C1CCCCC1.O=C(O)c1c(CCCN2CCC(N3CCCCC3)CC2)c(-c2ccccc2)nc2ccccc12>>C[C@H](NC(=O)c1c(CCCN2CCC(N3CCCCC3)CC2)c(-c2ccccc2)nc2ccccc12)C1CCCCC1,,C1CCOC1,,CCN(CC)CC,,test
US05068356,CC(C)(C)c1cc(CCC(=O)NN)cc(C(C)(C)C)c1O.CCCCCCCCCCCCCCC1CC(=O)OC1=O>>CCCCCCCCCCCCCCC1CC(=O)N(NC(=O)CCc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C1=O,,O,,Cc1ccccc1,,test
US20060264428A1,CI.COC(=O)[C@@H]1CC(=O)N([C@H](C)c2ccccc2)C1>>COC(=O)C1(C)CC(=O)N([C@H](C)c2ccccc2)C1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20160068559A1,CC(C)N(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21)C(=O)CCCC(=O)Nc1ccc(C(C)(C)C)cc1N>>CC(C)N(C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@@H]21)C(=O)CCCc1nc2cc(C(C)(C)C)ccc2[nH]1,,CC(=O)O,,,,test
US20160108059A1,CCN1CC2CC(O)c3c(Br)c(=O)c(OC)c(n32)C1=O.CO.CS(C)=O.NCc1ccc(F)cc1F>>CCN1CC2CC(O)c3c(C(=O)NCc4ccc(F)cc4F)c(=O)c(OC)c(n32)C1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,CCN(C(C)C)C(C)C,,test
US20100249099A1,COc1cccc2c1nc(C(F)F)n2-c1nc(C2CCOCC2)nc(N2CCNCC2)n1.CS(=O)(=O)Cl>>COc1cccc2c1nc(C(F)F)n2-c1nc(C2CCOCC2)nc(N2CCN(S(C)(=O)=O)CC2)n1,,ClCCl,,O,O=C([O-])[O-].[K+].[K+],test
US05556864,COc1ccccc1CCCCc1ccccc1OCCCN(C)C.Cl>>COc1ccccc1CCCCc1ccccc1OCCCN(C)C.Cl,,C1COCCO1,CCOC(C)=O,,,test
US05192749,CC(=O)OC(C)=O.Cc1cn([C@H]2CC[C@@](C=NO)(CO)O2)c(=O)[nH]c1=O>>CC(=O)OC[C@]1(C#N)CC[C@H](n2cc(C)c(=O)[nH]c2=O)O1,,CC(=O)OC(C)=O,,CC(=O)[O-].[Na+],,test
US20160128984A1,CN1CCN(C(=O)CCCCN)CC1.O=C(O)c1cc(-c2ccccc2)on1>>CN1CCN(C(=O)CCCCNC(=O)c2cc(-c3ccccc3)on2)CC1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070027178A1,CC(C)(C)OC(=O)N1CCc2[nH]c3c(Cl)c(Cl)ccc3c2C1.COCCOC>>Cn1c2c(c3ccc(Cl)c(Cl)c31)CN(C(=O)OC(C)(C)C)CC2,,O,,[K+].[OH-],,test
US20130184273A1,Cc1nc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCCC4)cc3)c(-c3ccccc3)cn2n1>>Cc1nc2nc(-c3ccc(C4(N)CCCC4)cc3)c(-c3ccccc3)cn2n1,,C1COCCO1,,Cl,,test
US20090018180A1,Fc1cc(Cl)ccc1CBr.S=C1NCCN1>>Br.Fc1cc(Cl)ccc1CSC1=NCCN1,,CC#N,,,,test
US20140303164A1,CC(C)(C)[Si](C)(C)O[C@@H]1C[C@H]2C[C@H]2[C@@H]1O.COCCl>>COCO[C@@H]1[C@H](O[Si](C)(C)C(C)(C)C)C[C@H]2C[C@H]21,CN(C)c1ccncc1,ClCCl,,CCN(C(C)C)C(C)C,,test
US05047411,CC(=O)Nc1cccc(C)n1.O=Cc1ccc([N+](=O)[O-])c(OCc2ccccc2)c1>>CC(=O)Nc1cccc(C=Cc2ccc([N+](=O)[O-])c(OCc3ccccc3)c2)n1,,ClC(Cl)Cl,,CC(=O)OC(C)=O,,test
US05061712,CC(C)(C)C=O.NC1CCNC1>>CC(C)(C)C=NC1CCNC1,,Cc1ccccc1,,,,test
US20100184719A1,[N-]=[N+]=NC[C@@H]1CN(c2ccc(Cl)cn2)C(=O)O1>>NC[C@@H]1CN(c2ccc(Cl)cn2)C(=O)O1,,C1CCOC1,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04464387,CCCN=C=O.O=C(O)CNc1ccccc1>>CCCN1C(=O)CN(c2ccccc2)C1=O,,Cc1ccccc1,,,,test
US20090209607A1,COC(=O)c1cc(Br)c(Cl)o1.Cn1nccc1B1OC(C)(C)C(C)(C)O1>>COC(=O)c1cc(-c2ccnn2C)c(Cl)o1,CC(C)(C)[P]([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)(C(C)(C)C)C(C)(C)C,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20040167182A1,CC(C)(C)OC(=O)C1(S(=O)(=O)c2ccc(-c3ccc(OC(F)(F)C(F)F)cc3)cc2)CCN(Cc2ccccc2)CC1>>CC(C)(C)OC(=O)C1(S(=O)(=O)c2ccc(-c3ccc(OC(F)(F)C(F)F)cc3)cc2)CCNCC1,[Pd],CCO,,O=C[O-].[NH4+],,test
US20120040954A1,CC(=O)NC1CCN(c2ccc(C=O)cc2)CC1.CCI>>CCN(C(C)=O)C1CCN(c2ccc(C=O)cc2)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20070249670A1,COC(=O)[C@@H](NC(=O)c1ncc(Cl)cc1N)C1CCCCC1.Cc1cc(C)c(N=C=O)c(C)c1>>COC(=O)[C@@H](NC(=O)c1ncc(Cl)cc1NC(=O)Nc1c(C)cc(C)cc1C)C1CCCCC1,,CCOC(C)=O,c1ccncc1,,,test
US20040157890A1,CC(C)[Si](Cl)(C(C)C)C(C)C.Cc1ccsc1CO>>Cc1ccsc1CO[Si](C(C)C)(C(C)C)C(C)C,,C1CCOC1,CCOC(C)=O,[H][H],[H-].[Na+],test
US20100179216A1,BrCCCc1cccc(Br)c1.CC(C)(C)OC(=O)NC1(/C=C/c2ccc(O)c(C(F)(F)F)c2)COC(C)(C)OC1>>CC(C)(C)OC(=O)NC1(/C=C/c2ccc(OCCCc3cccc(Br)c3)c(C(F)(F)F)c2)COC(C)(C)OC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20120165347A1,C#CC(C)(C)C.CC1=NC2(N=C1N)c1cc(Br)ccc1CC21CCC1>>CC1=NC2(N=C1N)c1cc(C#CC(C)(C)C)ccc1CC21CCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,CCN(CC)CC,,test
US20070088071A1,BrCc1ccccc1.CCCCC(=O)c1cc2cc(Cl)ccc2[nH]1>>CCCCC(=O)c1cc2cc(Cl)ccc2n1Cc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20090318408A1,COc1cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2OC)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C>>COc1cc(C(=O)NC2CCNCC2OC)ccc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150353489A1,CCI.COC(=O)Cc1c[nH]c2ccc(O)cc12>>CCOc1ccc2[nH]cc(CC(=O)OC)c2c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20060183759A1,C=CC(=O)OC.Cc1sc2nc(S)n(-c3ccccc3)c(=O)c2c1-c1ccccc1>>COC(=O)CCSc1nc2sc(C)c(-c3ccccc3)c2c(=O)n1-c1ccccc1,,CO,,CCN(CC)CC,,test
US20080207900A1,CCOC(=O)[C@H]1CCC(c2cc(F)c(F)c(F)c2)=N1>>CCOC(=O)[C@H]1CC[C@@H](c2cc(F)c(F)c(F)c2)N1,[Pd],CCO,,,,test
US03951976,CC(C)(C)c1nnc(N=C=O)s1.CNCCC=O>>CN(CCC=O)C(=O)Nc1nnc(C(C)(C)C)s1,,c1ccccc1,,,,test
US20060110743A1,CCOC(=O)c1ccc(N)c(Br)c1>>Nc1ccc(C(=O)O)cc1Br,,CO,,O,[Na+].[OH-],test
US20090069296A1,COc1cc2c(cc1OC)CCN(C(=O)CCN(CC1Cc3cc(OC(=O)N4CC5CCCC5C4)ccc31)C(=O)OC(C)(C)C)CC2>>COc1cc2c(cc1OC)CCN(C(=O)CCNCC1Cc3cc(OC(=O)N4CC5CCCC5C4)ccc31)CC2,,CCO,Cl,,,test
US20160024016A1,COCCCNC(=O)[C@H]1CC(c2nn(C3CCCCO3)cc2CN(C)CCN(C)C(=O)OC(C)(C)C)CCC1(C)C>>CNCCN(C)Cc1c[nH]nc1[C@@H]1CCC(C)(C)[C@@H](C(=O)NCCCOC)C1,,C1COCCO1,,Cl,,test
US04221794,CC(O)Cn1cnc2c(Cl)ncnc21.N>>CC(O)Cn1cnc2c(N)ncnc21,,[Cl-],[NH4+],,,test
US20090291940A1,CC(C)(C)OC(=O)N1CCN(c2nc(N[C@H]3CCN(C(=O)Cc4ccccc4)C3)nc3ccccc23)CC1>>O=C(Cc1ccccc1)N1CC[C@H](Nc2nc(N3CCNCC3)c3ccccc3n2)C1,,ClC(Cl)Cl,,[Na+].[OH-],,test
US20110144146A1,CCC(=O)NCc1nc2cc(NS(=O)(=O)c3ccc(C(C)C)cc3)ccc2[nH]1>>CCCNCc1nc2cc(NS(=O)(=O)c3ccc(C(C)C)cc3)ccc2[nH]1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20150307451A1,BrCc1ccc(-n2cccn2)cc1.COC(=O)c1cc(B2OC(C)(C)C(C)(C)O2)c(OC)cc1O>>COC(=O)c1cc(Cc2ccc(-n3cccn3)cc2)c(OC)cc1O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,O,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20140221332A1,C#Cc1cccc(F)c1.CCOC(=O)c1ccc(Br)cc1>>CCOC(=O)c1ccc(C#Cc2cccc(F)c2)cc1,[Cu]I,CN(C)C=O,O,CCN(CC)CC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20030233015A1,C[C@@H](CN1C(=O)c2ccccc2C1=O)c1ccc([N+](=O)[O-])cc1>>C[C@@H](CN)c1ccc([N+](=O)[O-])cc1,,Cc1ccccc1,,NN,,test
US03948928,CCOC(=N)c1noc2cc([N+](=O)[O-])ccc12.N>>N=C(N)c1noc2cc([N+](=O)[O-])ccc12,,CCO,,Cl,,test
US05442062,BrCC1CO1.OCC1=CC=CCC1>>C1=CCCC(COCC2CO2)=C1,,CN(C)C=O,O,[H-].[Na+],,test
US20030087902A1,CCOC(=O)c1[nH]c2ccc(OCc3ccccc3)cc2c1Br.Fc1ccc(CBr)cc1>>CCOC(=O)c1c(Br)c2cc(OCc3ccccc3)ccc2n1Cc1ccc(F)cc1,,CN(C)C=O,,[H-].[Na+],,test
US20070001154A1,N#CCCSc1cc(NC(=O)c2ccc([N+](=O)[O-])cc2)c(SCCC#N)cc1N.O=C(O)c1ccc(O)cc1>>N#CCCSc1cc(NC(=O)c2ccc([N+](=O)[O-])cc2)c(SCCC#N)cc1NC(=O)c1ccc(O)cc1,,CN1CCCC1=O,,,,test
US20030083315A1,COc1ccc(NCc2cccc3ccccc23)c([N+](=O)[O-])c1>>COc1ccc(NCc2cccc3ccccc23)c(N)c1,[Zn],CCO,,C1COCCO1,[Na+].[OH-],test
US20070281936A1,Cc1ccc(C)c(C#N)n1.O>>Cc1ccc(CO)nc1C#N,O=S(=O)(O)O,CC(=O)OC(C)=O,,O=C([O-])O.[Na+],,test
US20060041123A1,COc1ccc2nccc(O)c2n1.O=C1CCC(=O)N1Cl>>COc1ccc2ncc(Cl)c(O)c2n1,,CC(=O)O,,,,test
US20100136142A1,COc1cc(C#N)ccc1C=C(C(C)=O)C(=O)OCCC#N.Cc1cc(N)cc(=O)[nH]1>>COc1cc(C#N)ccc1C1C(C(=O)OCCC#N)=C(C)Nc2cc(C)[nH]c(=O)c21,,CC(C)O,,,,test
US20140179733A1,CC(C)c1c(N)cnn1-c1ccc(F)cc1.Cc1nc(C(F)(F)F)nn1C(C)C(=O)O>>Cc1nc(C(F)(F)F)nn1C(C)C(=O)Nc1cnn(-c2ccc(F)cc2)c1C(C)C,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080096868A1,CN(C)CCCC(=O)O.NC(=O)c1cnn(-c2ccccc2)c1N>>CN(C)CCCc1nc2c(cnn2-c2ccccc2)c(=O)[nH]1,,O,,Cl,N,test
US20160102107A1,COc1cc([N+](=O)[O-])cn2c(C(F)F)nnc12>>COc1cc(N)cn2c(C(F)F)nnc12,[Pd],CO,,,,test
US04419516,NCc1ccccn1.S=C=Nc1ccccc1>>S=C(NCc1ccccn1)Nc1ccccc1,,c1ccccc1,,,,test
US20150087646A1,NC1(c2ccccc2C(F)(F)F)CC1.O=C(O)c1ccc(-n2nc(-c3c(F)cccc3Cl)[nH]c2=O)cc1>>O=C(NC1(c2ccccc2C(F)(F)F)CC1)c1ccc(-n2nc(-c3c(F)cccc3Cl)[nH]c2=O)cc1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20060247238A1,CC(C)(C)OC(=O)N1C[C@@H](O)[C@H](CNC(=O)c2ccc(Cl)s2)C1>>CC(C)(C)OC(=O)N1CC(=O)[C@H](CNC(=O)c2ccc(Cl)s2)C1,,ClCCl,,CCN(CC)CC,,test
US20090048290A1,CS(=O)(=O)O.O=C(N[C@@H]1C2CCN(CC2)[C@H]1Cc1cccnc1)c1cc2ccccc2o1>>CS(=O)(=O)O.O=C(N[C@@H]1C2CCN(CC2)[C@H]1Cc1cccnc1)c1cc2ccccc2o1,,CCO,,,,test
US20110112096A1,CC(C)(C)OC(=O)N1CCC(c2ccc(N)c3ccccc23)CC1.Cc1cc(Nc2nc(Cl)ncc2Cl)nn1C1CCCCO1>>Cc1cc(Nc2nc(Nc3ccc(C4CCNCC4)c4ccccc34)ncc2Cl)n[nH]1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070105919A1,C1COCCN1.Cc1cccc(C(=O)c2sc(N)nc2-c2ccco2)n1.O=C(Br)CBr>>Cc1cccc(C(=O)c2sc(NC(=O)CN3CCOCC3)nc2-c2ccco2)n1,,C1CCOC1,O,CCN(CC)CC,,test
US05849779,CCOC(=O)c1cnn(C)c1N.O=C=Nc1ccccc1>>CCOC(=O)c1cnn(C)c1NC(=O)Nc1ccccc1,,c1ccccc1,,CCN(CC)CC,,test
US20150210722A1,CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)n(-c2cccc(CP(C)(C)=O)c2)n1.Cc1cc(N)cc2cn[nH]c12>>Cc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)nn4-c4cccc(CP(C)(C)=O)c4)c4ccccc34)n2)cc2cn[nH]c12,,C1CCOC1,CN(C)C=O,Cl,,test
US20080114006A1,CN(C)CCN.CNc1ncc2cc(-c3cc(NC(=O)Nc4cc(C5CCCC5)nn4C)c(F)cc3C)c(=O)n(C)c2n1>>Cc1cc(F)c(NC(=O)Nc2cc(C3CCCC3)nn2C)cc1-c1cc2cnc(NCCN(C)C)nc2n(C)c1=O,,C1CCOC1,CCOC(C)=O,,,test
US07923450B2,BrBr.Cc1ccc(C2CCCCC2=O)cc1F>>Cc1ccc(C2CCCC(Br)C2=O)cc1F,,ClC(Cl)Cl,,,,test
US20110077236A1,CC(C)CC(NC(=O)OC(C)(C)C)C(=O)CCl.Nc1cc(Cl)ccn1>>CC(C)C[C@H](NC(=O)OC(C)(C)C)c1cn2ccc(Cl)cc2n1,,CO,,,,test
US09248117B2,CC(C)(C)OCl.COCCOCCOCCN1C(=O)C(C)(C)NC1(C)C>>COCCOCCOCCN1C(=O)C(C)(C)N(Cl)C1(C)C,,CO,,,,test
US20070232615A1,CN(Cc1cn2c(N3CCN(C(=O)OC(C)(C)C)CC3)cccc2n1)C1CCCc2cccnc21>>CN(Cc1cn2c(N3CCNCC3)cccc2n1)C1CCCc2cccnc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US04933333,COc1ccc(CCl)cc1.O=C(O)[C@@H]1C[C@@H](O)CN1C(=O)OCc1ccc([N+](=O)[O-])cc1>>COc1ccc(COC(=O)[C@@H]2C[C@@H](O)CN2C(=O)OCc2ccc([N+](=O)[O-])cc2)cc1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,,test
US04927941,COCCO.ClCC1CO1>>COCCOCC(O)CCl,,CCOCC,,O=S(=O)(O)O,,test
US04024272,CN1c2cccc(O)c2C(=O)CC1CC#N.CN1c2cccc(O)c2C(=O)CC1CC=C1N=C(c2ccccc2)SC1=O.CN1c2cccc(O)c2C(=O)CC1CC=O.O=C1CN=C(c2ccccc2)S1>>CN1c2cccc(O)c2C(=O)C2C(O)C3C(=O)C(C(N)=O)=C(O)C(NC(=S)c4ccccc4)C3CC21,[Ni],c1ccncc1,,,,test
US20160083370A1,C1CNCCN1.N#Cc1ccnc(Cl)n1>>N#Cc1ccnc(N2CCNCC2)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090076070A1,NC(=NOC(=O)c1cnc(Cl)c(Cl)c1)c1cccc2[nH]ccc12>>Clc1cc(-c2nc(-c3cccc4[nH]ccc34)no2)cnc1Cl,,C1COCCO1,,,,test
US20100256097A1,CCN(CC)S(F)(F)F.OCC1COCCN1Cc1nccc(Cl)n1>>FCC1COCCN1Cc1nccc(Cl)n1,,ClCCl,,O=C([O-])O.[Na+],,test
US20160244417A1,COC(=O)[C@@H]1CC2CC2C[C@H]1C(=O)Cl.C[Si](C)(C)C=[N+]=[N-].Cl>>COC(=O)[C@@H]1CC2CC2C[C@H]1C(=O)CCl,,C1CCOC1,CC#N,,,test
US20070049571A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.NCc1ccccc1.O=C(Cl)c1ccccc1I>>CC(C)(C)OC(=O)N1CC=C(N(Cc2ccccc2)C(=O)c2ccccc2I)CC1,,Cc1ccccc1,,O,,test
US04725600,COc1ccc(-c2cc(=Nc3c(C)cc(C)cc3C)n(C)c(NNC=O)n2)cc1OC>>COc1ccc(-c2cc(=Nc3c(C)cc(C)cc3C)n(C)c3nncn23)cc1OC,,O,,[Na+].[OH-],,test
US04174397,ClCl.O=C1CCc2cc(Cl)ccc21>>O=C1c2ccc(Cl)cc2CC1Cl,,CC(=O)O,,Cl,,test
US20090076046A1,COc1ccc(CN(C(=O)OC(C)(C)C)c2ccc(C(=O)c3c[nH]c4ncc(Cl)cc34)cn2)cn1>>COc1ccc(CNc2ccc(C(=O)c3c[nH]c4ncc(Cl)cc34)cn2)cn1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[K+].[K+],test
US05998433,CN(C)Cc1cc2c(o1)CCN(C(=O)c1cccc(C(=O)c3ccccc3)c1)C2.Cl>>CN(C)Cc1cc2c(o1)CCN(C(=O)c1cccc(C(=O)c3ccccc3)c1)C2.Cl,,CCOC(C)=O,CO,,,test
US20130109682A1,CC(C)(C)[Si](C)(C)Cl.CC1OC(c2ccncc2[N+](=O)[O-])CC(NCc2ccccc2)C1O>>CC1OC(c2ccncc2[N+](=O)[O-])CC(NCc2ccccc2)C1O[Si](C)(C)C(C)(C)C,,CN(C)C=O,,O,c1c[nH]cn1,test
US20140343032A1,C=O.O=C(OCc1ccccc1)N1C2CNCC1COC2>>CN1CC2COCC(C1)N2,,CO,,[BH4-].[Na+],,test
US20090099169A1,CCOC(=O)c1cc(C)n(Cc2cc(C#N)cc3cc(C(C)C)oc23)n1>>Cc1cc(C(=O)O)nn1Cc1cc(C#N)cc2cc(C(C)C)oc12,,CCO,,[Na+].[OH-],,test
US20090253687A1,COC(=O)c1ccc2c(c1)SC(c1ccccc1)C(c1ccc3c(c1)NC(=O)CO3)=C2>>O=C1COc2ccc(C3=Cc4ccc(C(=O)O)cc4SC3c3ccccc3)cc2N1,,C1CCOC1,CCO,[Na+].[OH-],,test
US04275071,Cc1cc(C)c(C)c(C(=O)CBr)c1C.c1c[nH]cn1>>Cc1cc(C)c(C)c(C(=O)Cn2ccnc2)c1C,,O,,CN(C)C=O,,test
US04609753,COC(=O)CCNc1cc(Oc2ccc(S(C)(=O)=O)cc2Cl)ccc1[N+](=O)[O-].N>>CS(=O)(=O)c1ccc(Oc2ccc([N+](=O)[O-])c(NCCC(N)=O)c2)c(Cl)c1,,CO,,,,test
US20060052384A1,COc1c(C2CCN(CCCCNC(=O)c3cc(-c4ccc(C#N)cc4)nn3CCOC3CCCCO3)CC2)ccc2c1CCCC2>>COc1c(C2CCN(CCCCNC(=O)c3cc(-c4ccc(C#N)cc4)nn3CCO)CC2)ccc2c1CCCC2,,C1CCOC1,,Cl,,test
US05559230,CNC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc21.N#CCO>>Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(N(C)CC#N)c3ccccc32)cc1,,CO,,,,test
US20140275528A1,Cn1c(=O)c2c(nc(CO)n2Cc2cccc(Br)c2)n(C)c1=O>>Cn1c(=O)c2c(nc(C=O)n2Cc2cccc(Br)c2)n(C)c1=O,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US07427623B2,CC(=O)Nc1ccc(-c2coc(N)c2C#N)cc1.CCOC(OCC)OC(C)=O>>CCOC=Nc1occ(-c2ccc(NC(C)=O)cc2)c1C#N,,CC(=O)O,,,,test
US06107297,COC(=O)c1cnc(Cl)nc1NCC(=O)OC(C)(C)C.Cc1ccc2c(c1)C=Cc1cc(C)ccc1C2c1c[nH]c(=O)[nH]c1=O>>COC(=O)c1cnc(-n2cc(C3c4ccc(C)cc4C=Cc4cc(C)ccc43)c(=O)[nH]c2=O)nc1NCC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06197783B1,Cc1nc2c3c(ccn2c1C)C(=O)C(O)C(c1ccccc1)N3>>Cc1nc2c3c(ccn2c1C)C(O)C(O)C(c1ccccc1)N3,,CO,,[BH4-].[Na+],,test
US20120142714A1,C[C@@H](COc1ccc(-c2nc3ccc(OCC4CC4)cc3o2)nc1)NC(=O)OC(C)(C)C>>COC(=O)N[C@@H](C)COc1ccc(-c2nc3ccc(OCC4CC4)cc3o2)nc1,,CCOC(C)=O,,Cl,,test
US20150289506A1,COC(=O)c1cc2c(Br)cccc2s1.OB(O)c1ccccc1>>COC(=O)c1cc2c(-c3ccccc3)cccc2s1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,[Cl-].[Na+],O=C([O-])[O-].[Li+],test
US20090156575A1,CCOC(=O)CC(=O)OCC.O=C(O)c1ccncc1Br>>CCOC(=O)C(C(=O)OCC)c1cnccc1C(=O)O,,O,,[H-].[Na+],,test
US20040254183A1,CC(C)CCBr.Cn1ccnc1-c1c2c(=O)n(C)c(=O)[nH]c2nn1Cc1c[nH]c2ccc(Cl)cc12>>CC(C)CCn1c(=O)n(C)c(=O)c2c(-c3nccn3C)n(Cc3c[nH]c4ccc(Cl)cc34)nc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090181928A1,CC(C)(C)O.COC(=O)CNc1ccc(OCC(=O)OCC[Si](C)(C)C)cc1OCc1ccccc1.O=C=NS(=O)(=O)Cl>>COC(=O)CN(c1ccc(OCC(=O)OCC[Si](C)(C)C)cc1OCc1ccccc1)S(=O)(=O)NC(=O)OC(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20040192698A1,Clc1cccnc1.NCCN>>NCCNc1cccnc1,,O,,CC(C)(C)[O-].[K+],,test
US20050070545A1,CCOC(=O)c1c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn2c1CCCO.CCOP(OCC)OCC.CS(=O)(=O)OS(C)(=O)=O>>CCOC(=O)c1c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn2c1CCCP(=O)(OCC)OCC,,ClCCl,,CCN(CC)CC,[I-].[Na+],test
US06613942B1,COc1cc(OCCN2CCc3ccccc3C2)ccc1C=O.NNC(=O)c1ccc(O)c(N)c1>>COc1cc(OCCN2CCc3ccccc3C2)ccc1C=NNC(=O)c1ccc(O)c(N)c1,,CC(C)O,,,,test
US20140171408A1,C[Si](C)(C)Br.N#Cc1cccc(Cl)c1-c1nc2ccnc(Cl)c2s1>>N#Cc1cccc(Cl)c1-c1nc2ccnc(Br)c2s1,,CCC#N,,,,test
US20090048269A1,COC(=O)c1cccc(Nc2cc(Oc3cc(C)c(C)nc3-c3ccccn3)ccn2)c1>>Cc1cc(Oc2ccnc(Nc3cccc(C(=O)O)c3)c2)c(-c2ccccn2)nc1C,,CO,,Cl,[Na+].[OH-],test
US20030232838A1,C=O.CCCOc1ccc(S(=O)(=O)N2CCNCC2)cc1-c1cc2c(=O)n(C)c(=O)n(CCC)c2[nH]1>>CCCOc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1-c1cc2c(=O)n(C)c(=O)n(CCC)c2[nH]1,[Pd],,,,,test
US20080119407A1,CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1nc2cc(C(=O)O)ccc2o1>>CCC(CC)(c1ccc(OCC(O)C(C)(C)C)c(C)c1)c1nc2cc(C(=O)O)ccc2o1,,C1CCOC1,,[BH4-].[Na+],,test
US20070135452A1,Cc1cc(C)c(Nc2nc3cc(CO)cc([N+](=O)[O-])c3s2)c(C)c1.O=S(Cl)Cl>>Cc1cc(C)c(Nc2nc3cc(CCl)cc([N+](=O)[O-])c3s2)c(C)c1,,ClC(Cl)Cl,,O,O=C([O-])O.[Na+],test
US20140171405A1,COc1cc(OC)c(F)c(-c2cc3c(cn2)c(I)nn3C2CCCCO2)c1.O=S(=O)(Cl)Cl>>COc1cc(OC)c(Cl)c(-c2cc3c(cn2)c(I)nn3C2CCCCO2)c1F,,ClCCl,,,,test
US20120214837A1,COc1cc2cc(O)nc(C)c2cc1OC.ClCc1ccc2ccccc2n1>>COc1cc2c(C)nc(O)c(Cc3ccc4ccccc4n3)c2cc1OC,,Cc1ccccc1,O,Cl,[K+].[OH-],test
US20100204272A1,CC(C)(C)OC(=O)N1CCC(N(Cc2ccccc2)Cc2ccccc2)CC1>>c1ccc(CN(Cc2ccccc2)C2CCNCC2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20060135578A1,CC(=O)C(C)Cl.CCOC(=O)C1CCN(C(N)=S)CC1>>CCOC(=O)C1CCN(c2nc(C)c(C)s2)CC1,,CC(C)O,,,,test
US20120010235A1,CCNC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F.O=CC1CC1>>CCNC(=O)[C@H]1[C@H](c2cccc(Cl)c2F)[C@@](C#N)(c2ccc(Cl)cc2F)[C@H](CC(C)(C)C)N1CC1CC1,,CC(=O)O,ClCCl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20070197622A1,CN(C)S(=O)(=O)n1ccnc1[Si](C)(C)C(C)(C)C.Fc1cccc(CBr)c1F>>CN(C)S(=O)(=O)n1cc(Cc2cccc(F)c2F)nc1[Si](C)(C)C(C)(C)C,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20110269705A1,CC(=O)Nc1cc2ccccc2cc1O.CCCI>>CCCOc1cc2ccccc2cc1NC(C)=O,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110251173A1,CS(=O)(=O)Cl.NCc1ccc(Br)c(Cl)c1>>CS(=O)(=O)NCc1ccc(Br)c(Cl)c1,,ClCCl,,c1ccncc1,,test
US20140073589A1,CC(=O)OC[C@@H](OC(C)=O)[C@@H](O[C@@H]1O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)C(=O)N[C@@H](C)Cc1ccccc1>>C[C@@H](Cc1ccccc1)NC(=O)[C@H](O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)CO,,CCO,CO,C[O-].[Na+],,test
US20100113547A1,C=CCOCC1(c2cccc(C(F)(F)F)c2)NC(=O)NC1=O.N#Cc1ccc(Br)cc1C(F)(F)F>>C=CCOCC1(c2cccc(C(F)(F)F)c2)NC(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C1=O,O=[Cu],CC(=O)N(C)C,,,,test
US20040259910A1,CC(=O)OC(C)=O.CCOC(=O)N1C=Cc2cc(OCCCO)c(OC)cc2C1Cc1cccc(OC)c1>>CCOC(=O)N1C=Cc2cc(OCCCOC(C)=O)c(OC)cc2C1Cc1cccc(OC)c1,,c1ccncc1,,,,test
US05041455,CCOCCOCCO.Clc1nsnc1-c1cccnc1>>CCOCCOCCOc1nsnc1-c1cccnc1,,C1CCOC1,,O,[H-].[Na+],test
US20050113419A1,CCCc1c(OCCCBr)ccc2c(C(F)(F)F)noc12.CN>>CCCc1c(OCCCNC)ccc2c(C(F)(F)F)noc12,,C1CCOC1,,,,test
US20080085910A1,COC(=O)[C@H](C/C=C/c1ccc(N(C)c2ncccn2)cc1)NC(=O)c1c(Cl)cccc1Cl>>CN(c1ccc(/C=C/C[C@H](NC(=O)c2c(Cl)cccc2Cl)C(=O)O)cc1)c1ncccn1,,C1CCOC1,,O,[Li+].[OH-],test
US20080287431A1,COc1cccc2c1nc(C(F)F)n2-c1nc(Cl)cc(Cl)n1.C[C@H]1CNC[C@@H](C)O1>>COc1cccc2c1nc(C(F)F)n2-c1nc(Cl)cc(N2C[C@H](C)O[C@H](C)C2)n1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20100144760A1,COC(=O)c1nc(C)ccc1-n1cccn1>>Cc1ccc(-n2cccn2)c(C(=O)O)n1,,C1CCOC1,O,[Li+].[OH-],,test
US20080070928A1,CC(=O)c1ccc(Oc2cc3nc(-c4ccccn4)[nH]c3cc2C2CCCN2C(C)=O)cn1.[Li]C>>CC(=O)N1CCCC1c1cc2[nH]c(-c3ccccn3)nc2cc1Oc1ccc(C(C)(C)O)nc1,,C1CCOC1,,[Cl-].[NH4+],,test
US20160272617A1,CN(C)C1CCC(N)CC1.Cc1cc(C(=O)O)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nc(C(F)(F)C(F)(F)C(=O)O)n[nH]3)cc2)cc1>>Cc1cc(C(=O)NC2CCC(N(C)C)CC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc(-c3nc(C(F)(F)C(F)(F)C(=O)O)n[nH]3)cc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06479531B1,CCOC(=O)CC(=O)CC12CC3CC(CC(C3)C1)C2.O=C(CBr)c1ccccc1>>CCOC(=O)C(CC(=O)c1ccccc1)C(=O)CC12CC3CC(CC(C3)C1)C2,,CC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US20040147756A1,O=C(Oc1ccccc1)[C@]1(C(F)(F)F)CO1>>O=C(O)[C@]1(C(F)(F)F)CO1,,CO,,O,[Na+].[OH-],test
US20060135516A1,COC(=O)c1nn(C(C)=O)c2ccc(NC(C)=O)c(Br)c12.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COC(=O)c1nn(C(C)=O)c2ccc3nc(C)sc3c12,,Cc1ccccc1,,,,test
US20110213028A1,CC(C)(C)OC(=O)OC(C)(C)C.CN(CCN)CCN>>CN(CCN)CCNC(=O)OC(C)(C)C,,ClCCl,,,,test
US20020193403A1,CC1(C)CC(=O)c2cc(C#C[Si](C)(C)C)ccc2S1>>C#Cc1ccc2c(c1)C(=O)CC(C)(C)S2,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20060241115A1,COc1cc2nccc(Oc3ccc4c(N=C=S)cccc4c3)c2cc1OC.COc1ccc(N)cc1>>COc1ccc(NC(=S)Nc2cccc3cc(Oc4ccnc5cc(OC)c(OC)cc45)ccc23)cc1,,ClCCl,,,,test
US20120028973A1,BrP(Br)Br.OCc1ccc(Cc2ccc(OC(F)(F)F)cc2)cc1>>FC(F)(F)Oc1ccc(Cc2ccc(CBr)cc2)cc1,,ClCCl,,CCOC(C)=O,,test
US20150336986A1,CON(C)C(=O)CCn1cc2c(c1-c1ccccc1)c(=O)n(C)c(=O)n2C.Clc1csc(Br)n1>>Cn1c(=O)c2c(-c3ccccc3)n(CCC(=O)c3nc(Cl)cs3)cc2n(C)c1=O,,C1CCOC1,,,,test
US20070135479A1,CC(C)(C)OC(=O)N1CCCC(Nc2ccc3c(N)nccc3c2)C1>>Nc1nccc2cc(NC3CCCNC3)ccc12,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110009454A1,COCc1ccc(C(=O)O)c(N)n1.NCc1cccc(Oc2ccc(OC(F)(F)F)cc2)c1>>COCc1ccc(C(=O)NCc2cccc(Oc3ccc(OC(F)(F)F)cc3)c2)c(N)n1,,CN(C)C=O,O,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20160237091A1,NCc1cc2c(Br)nn(C(c3ccccc3)(c3ccccc3)c3ccccc3)c2cc1[N+](=O)[O-].O=Cc1cscn1>>O=[N+]([O-])c1cc2c(cc1CNCc1cscn1)c(Br)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1,CC(=O)O,,,[BH3-]C#N.[Na+],,test
US20120029190A1,O=C(NC1CC(c2ccc(F)cc2Cl)CCC1O)c1ccccn1>>O=C(NC1CC(c2ccc(F)cc2Cl)CCC1=O)c1ccccn1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US05631401,C1CCOC1.CCCN.CCN(CC)CC.CCN=C=NCCCN(C)C.On1nnc2ccccc21>>CCCNC(=O)[C@H](C)CCCc1ccccc1,,C1CCOC1,,Cl,O,test
US20120232056A1,COC(=O)c1ccc2nc(-c3ccc4[nH]ncc4c3)c(N3CCN(c4ccccn4)C[C@@H]3C)nc2c1>>C[C@H]1CN(c2ccccn2)CCN1c1nc2cc(C(=O)O)ccc2nc1-c1ccc2[nH]ncc2c1,,CO,O,Cl,[Na+].[OH-],test
US20140065070A1,C#C[Sn](CCCC)(CCCC)CCCC.COC(=O)CN=[N+]=[N-]>>CCCC[Sn](CCCC)(CCCC)c1cn(CC(=O)OC)nn1,,Cc1ccccc1,,,,test
US04789396,CC(=O)Cl.O=C1CC(=O)CC(CCSc2ccc(C(F)(F)F)cc2)C1>>CC(=O)OC1=CC(=O)CC(CCSc2ccc(C(F)(F)F)cc2)C1,,C1CCOC1,,CCN(CC)CC,,test
US20110311461A1,CCOC(=O)c1cccc(N)c1.COc1ccc(B(O)O)cn1.O=CC(=O)O>>CCOC(=O)c1cccc(NC(C(=O)O)c2ccc(OC)nc2)c1,,CC#N,,O,,test
US20070219220A1,CCCc1nn(CC)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4C[C@H](C)N[C@H](C)C4)ccc3OCC)nc12.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>CCCc1nn(CC)c2c(=S)[nH]c(-c3cc(S(=O)(=O)N4C[C@H](C)N[C@H](C)C4)ccc3OCC)nc12,,Cc1ccccc1,,CO,ClC(Cl)Cl,test
US20140112945A1,COc1ccc(C2=NN(C3CCN(C(=O)[C@H](Cc4cccnc4)NC(=O)OC(C)(C)C)CC3)C(=O)C3(CCCC3)C2)cc1OC>>COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](N)Cc4cccnc4)CC3)C(=O)C3(CCCC3)C2)cc1OC,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20040033896A1,Cc1cnc(Cl)nc1C(=O)c1cccc(C(F)(F)F)c1.FC(F)(F)c1cc[nH]n1>>Cc1cnc(-n2ccc(C(F)(F)F)n2)nc1C(=O)c1cccc(C(F)(F)F)c1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20160095858A1,CC(C)(C)c1ccc(C#N)c(Cl)n1.Cc1cc(C)c(O)c(C)c1>>Cc1cc(C)c(Oc2nc(C(C)(C)C)ccc2C#N)c(C)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080045556A1,CCOC(=O)C1([NH3+])CC1.N#CSCC(=O)c1ccc(Br)cc1>>CCOC(=O)C1(Nc2nc(-c3ccc(Br)cc3)cs2)CC1,,CCO,,CCN(CC)CC,,test
US20080108638A1,CC(C)(C)OC(=O)Cn1c(SCc2ccccc2)nc2cc([N+](=O)[O-])ccc21>>O=C(O)Cn1c(SCc2ccccc2)nc2cc([N+](=O)[O-])ccc21,,ClCCl,O=C(O)C(F)(F)F,,,test
US20070054903A1,CC1(C)OB(c2ccc3cc(NC(=O)c4ccsc4)ccc3c2)OC1(C)C.O=C1Cc2ccc(Br)cc2N1>>O=C1Cc2ccc(-c3ccc4cc(NC(=O)c5ccsc5)ccc4c3)cc2N1,[Pd],O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20140142119A1,BrBr.O=C(O)C1CC2C=CC1C2>>O=C1OC2C(Br)C3CC1C2C3,,O,,O=C([O-])O.[Na+],,test
US20060063759A1,CC1(C)OB(c2ccc3c(c2)[nH]c(=O)n3CCN2CCOCC2)OC1(C)C.Fc1ccc2c(c1)OCc1c(F)cccc1C2=CBr>>O=c1[nH]c2cc(C=C3c4ccc(F)cc4OCc4c(F)cccc43)ccc2n1CCN1CCOCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20090247507A1,Nc1ncc(Br)c(Cl)c1[N+](=O)[O-].c1ccc(CN2CCNCC2)nc1>>Nc1ncc(Br)c(N2CCN(Cc3ccccn3)CC2)c1[N+](=O)[O-],,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20090186373A1,Nc1nccc(OCc2ccc(CNC(=O)C(F)(F)F)cc2)n1>>NCc1ccc(COc2ccnc(N)n2)cc1,,CO,,CN,,test
US20100197680A1,COC(=O)c1ccc(CCC(/C=C/c2ccccc2O)Cc2ccc(C(=O)OC)cc2)cc1.O=C1CCCN1CCCCl>>COC(=O)c1ccc(CCC(/C=C/c2ccccc2OCCCN2CCCC2=O)Cc2ccc(C(=O)OC)cc2)cc1,,C1COCCO1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20030033089A1,N#C[O-].Nc1c(C(=O)c2ccc3c(c2)OCO3)ccc2c1OCO2>>O=c1nc(-c2ccc3c(c2)OCO3)c2cc3c(cc2[nH]1)OCO3,,CC(=O)O,,O,,test
US20130072535A1,CON.O=C(CO)Cc1c(Cl)cc(Cl)cc1Cl>>CON=C(CO)Cc1c(Cl)cc(Cl)cc1Cl,,CO,,Cl,c1ccncc1,test
US20110060026A1,CCOC(=O)Cc1c(C)n(Cc2ccccc2S(=O)(=O)c2ccc(F)cc2)c2cc(F)ccc12>>Cc1c(CC(=O)O)c2ccc(F)cc2n1Cc1ccccc1S(=O)(=O)c1ccc(F)cc1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20140296231A1,Clc1ccc2ncc(-c3cc4ccccc4o3)n2n1.N[C@@H]1CCCC[C@H]1O>>N[C@@H]1CCCC[C@H]1Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20060063799A1,CC(C)(C)OC(=O)OC(C)(C)C.O=Cc1ccc2[nH]ccc2c1>>CC(C)(C)OC(=O)n1ccc2cc(C=O)ccc21,CN(C)c1ccncc1,CC#N,CCOC(C)=O,,,test
US20100190766A1,COC(=O)c1ccc(C2CCN(c3ccc(CN4CCOCC4)cc3)CC2)cc1>>O=C(O)c1ccc(C2CCN(c3ccc(CN4CCOCC4)cc3)CC2)cc1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20140350019A1,COC(=O)c1c(F)ccc(-c2cccc(F)c2)c1F>>O=C(O)c1c(F)ccc(-c2cccc(F)c2)c1F,,C1CCOC1,,CO,[Na+].[OH-],test
US20040116424A1,CCCCC(Br)C(=O)c1ccccc1.COC(=O)CC(=O)OC>>CCCCC(C(=O)c1ccccc1)C(C(=O)OC)C(=O)OC,,CS(C)=O,,[H-].[Na+],,test
US20070224370A1,O=C(O)CCCc1ccc2cc3ccccc3cc2c1.O=C1OC(=O)C2C1C1C(=O)OC(=O)C21>>O=C(O)CCCc1ccc2cc3ccccc3cc2c1.O=C1OC(=O)C2C1C1C(=O)OC(=O)C21,,CN1CCCC1=O,,,,test
US20130143892A1,Cc1nc(C(=O)O)c[nH]1.N#Cc1ccc(F)c(F)c1>>Cc1nc(C(=O)O)cn1-c1ccc(C#N)cc1F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06395737B1,CC(C)(C)OC(=O)N1CCNCC1.NCCCl>>CC(C)(C)OC(=O)N1CCN(CCN)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US05552551,O=C(CO)c1ccccc1.O=Cc1cccs1>>O=c1cc(-c2sccc2O)oc2ccccc12,,CCO,O,Cl,[Na+].[OH-],test
US04587262,CC1CC(=O)OC(=O)C1.Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl>>CC(CC(=O)O)CC(=O)Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl,,CCOCC,,CCN(CC)CC,,test
US05340802,CCC(O)Br.N[C@@H](CS)C(=O)O>>N[C@@H](CSCCCO)C(=O)O,,N,,[Na],,test
US20150025093A1,CCc1cc2c(Cl)ncnc2s1.NC1CCC(N)CC1>>CCc1cc2c(NC3CCC(N)CC3)ncnc2s1,,CN(C)C=O,,CCN(CC)CC,O,test
US20120184528A1,N#Cc1c(Br)ccnc1Br.OCc1ccccc1>>N#Cc1c(OCc2ccccc2)ccnc1Br,,CN(C)C=O,,[H-].[Na+],,test
US20100215632A1,CC(C)(C)OC(=O)NC1CCNCC1.O=[N+]([O-])c1ccccc1-c1cn2c(CCl)csc2n1>>CC(C)(C)OC(=O)NC1CCN(Cc2csc3nc(-c4ccccc4[N+](=O)[O-])cn23)CC1,,CC#N,,CCN(CC)CC,,test
US05622944,C1CCOC1.C[C@]12CCC(=O)C=C1CC[C@H]1[C@@H]3CC[C@H](O)[C@@]3(C)CC[C@@H]12.O=C(Cl)Cl>>C[C@]12CCC(=O)C=C1CC[C@H]1[C@@H]3CC[C@H](O)[C@@]3(C)CC[C@@H]12.O=C([O-])Cl,,C1CCOC1,Cc1ccccc1,,,test
US20100273764A1,CN(C)S(=O)(=O)c1ccc(Br)cc1.COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(C=O)cnc3Nc3ccc(OC)nc3)n2)cc1>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(C(O)c4cc(Br)ccc4S(=O)(=O)N(C)C)cnc3Nc3ccc(OC)nc3)n2)cc1,,C1CCOC1,,[Li]CCCC,,test
US20030191027A1,CCN(CC)C(=O)COc1c(S(=O)(=O)CC)ccc(C(=O)O)c1Cl.O=C1CCCC(=O)C1>>CCN(CC)C(=O)COc1c(S(=O)(=O)CC)ccc(C(=O)OC2=CC(=O)CCC2)c1Cl,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20160009744A1,CC(C)(C)[Si](C)(C)OCCCCC(O)(c1cccc(Cl)c1)c1csc(C2OCCO2)c1>>O=Cc1cc(C2(c3cccc(Cl)c3)CCCCO2)cs1,,C1CCOC1,O,Cl,,test
US20150210720A1,O=C(O)C(=O)CBr.O=C1CC(=O)CC2(CCC2)C1>>O=C(O)c1coc2c1C(=O)CC1(CCC1)C2,,CO,O,[K+].[OH-],,test
US20080114005A1,CCOC(=O)C(C)(C)Sc1ccc(NCCn2c(CC)nc3ccccc3c2=O)cc1>>CCc1nc2ccccc2c(=O)n1CCNc1ccc(SC(C)(C)C(=O)O)cc1,,CO,O,[Li+].[OH-],,test
US20040147561A1,CCOC(=O)c1cc(C(=O)CBr)c(=O)[nH]c1CC.NC(=S)CS(=O)(=O)c1ccccc1>>CCOC(=O)c1cc(-c2csc(CS(=O)(=O)c3ccccc3)n2)c(=O)[nH]c1CC,,CCO,,,,test
US20030171364A1,CCn1nc(C)c2c1C(=O)NCC(c1ccccc1OC)=N2>>CCn1nc(C)c2c1C(=O)NCC(c1ccccc1O)=N2,,ClCCl,,BrB(Br)Br,,test
US20130331374A1,CC(C)(C)[Si](C)(C)Cl.CC(C)(O)CO>>CC(C)(O)CO[Si](C)(C)C(C)(C)C,CN(C)c1ccncc1,ClCCl,,,,test
US20060135504A1,OC(c1ccc(C(F)(F)F)cc1)(c1ccc(C(F)(F)F)cc1)C1CCNCC1>>FC(F)(F)c1ccc(C(=C2CCNCC2)c2ccc(C(F)(F)F)cc2)cc1,,O=C(O)C(F)(F)F,,,,test
US20120258952A1,COc1cccc(CBr)n1.O=[N+]([O-])c1cccc2[nH]nc(I)c12>>COc1cccc(Cn2nc(I)c3c([N+](=O)[O-])cccc32)n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110110889A1,CI.Cc1cn(S(=O)(=O)c2ccccc2)c2ncccc12>>Cc1c(C)n(S(=O)(=O)c2ccccc2)c2ncccc12,,C1CCOC1,ClCCl,O,CC(C)[N-]C(C)C.[Li+],test
US20150025068A1,COC(=O)c1ccc(N)cc1O.O=S(=O)(Cl)c1c(Cl)sc(Cl)c1Cl>>COC(=O)c1ccc(NS(=O)(=O)c2c(Cl)sc(Cl)c2Cl)cc1O,,CC#N,Cc1ccccc1,c1ccncc1,,test
US20100029699A1,COc1ccc(COC(CCc2ccc(-c3ccccc3)cc2)C(CCO)C(=O)OC(C)(C)C)cc1.CS(=O)(=O)Cl>>COc1ccc(COC(CCc2ccc(-c3ccccc3)cc2)C(CCOS(C)(=O)=O)C(=O)OC(C)(C)C)cc1,,ClCCl,,CCN(CC)CC,,test
US20030220359A1,Brc1ccc(Oc2ccc(Br)cc2)cc1.Cc1ccc(-c2c(Cl)ncnc2NS(=O)(=O)C=Cc2ccccc2)cc1.OCCO>>Cc1ccc(-c2c(NS(=O)(=O)C=Cc3ccccc3)ncnc2OCCOc2ccc(Br)cc2)cc1,,COCCOC,,CC(C)(C)[O-].[K+],,test
US05504082,CCOC(=O)CN(CCSc1ccnc(CSc2nc3ccccc3[nH]2)c1C)Cc1ccccc1>>Cc1c(SCCN(CC(=O)O)Cc2ccccc2)ccnc1CSc1nc2ccccc2[nH]1,,CCO,,[Na+].[OH-],,test
US06187777B1,CC1CC(c2ncc3ncc(-c4ccccc4)c-3[nH]2)CC(c2ccccc2)N1.CO.Cl>>CC1CC(c2ncc3ncc(-c4ccccc4)c-3[nH]2)CC(c2ccccc2)N1.Cl.O,,CO,,CCOC(C)=O,,test
US20110105461A1,CCNCC.Cc1ccc(S(=O)(=O)OCC2COc3ccc(S(C)(=O)=O)cc3O2)cc1>>CCN(CC)CC1COc2ccc(S(C)(=O)=O)cc2O1,,CC#N,,,,test
US20140357614A1,CCCCNc1nccc(N2CC(NC(=O)OC(C)(C)C)C2)n1>>CCCCNc1nccc(N2CC(N)C2)n1,,O=CO,,CO,Cl,test
US20140227212A1,C(=NC1CCCCC1)=NC1CCCCC1.CCCCCC.N#CC(C(=O)O)=C(c1ccccc1)c1ccccc1.OCC1CC2C=CC1C2>>CCCCC(CC)COC(=O)C(C#N)=C(c1ccccc1)c1ccccc1,CN(C)c1ccncc1,CCCCCC,CCOC(C)=O,ClCCl,,test
US20160108046A1,CC(C)(C)OC(=O)N1C[C@H]2C(CCl)[C@H]2C1.Cc1ccc(-c2cc(NC(=O)OC(C)(C)C)nn2-c2ccc(C#N)cc2)cc1>>Cc1ccc(-c2cc(N(CC3[C@@H]4CN(C(=O)OC(C)(C)C)C[C@H]34)C(=O)OC(C)(C)C)nn2-c2ccc(C#N)cc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20060069255A1,Cc1cc(S(=O)(=O)O)c(N)cc1Cl.O=C=Nc1cccc(Br)c1>>Cc1cc(S(=O)(=O)O)c(NC(=O)Nc2cccc(Br)c2)cc1Cl,,C1CCOC1,CCOC(C)=O,CCN(CC)CC,,test
US20030100572A1,CCOC(=O)c1ccc(P(=O)(CP(=O)(OCC)OCC)OCC)cc1>>CCOP(=O)(CP(=O)(OCC)c1ccc(C(=O)O)cc1)OCC,,CO,O,[Li+].[OH-],,test
US06096780,Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CO)cc2)CCC3)cc1.O=S(Cl)Cl>>Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CCl)cc2)CCC3)cc1,,ClC(Cl)Cl,,O,c1ccncc1,test
US20050148631A1,CCOC(=O)Cc1cccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)n1>>Cc1c(S(=O)(=O)Nc2cccc(CCO)n2)sc2ccc(Cl)cc12,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04898862,CCOC(=O)COc1ccc(C2=NNC(=O)NC2C)cc1Cl.NN>>CC1NC(=O)NN=C1c1ccc(OCC(=O)NN)c(Cl)c1,,CCO,,O,,test
US20080227823A1,CC(C)(C)OC(=O)NCC(=O)O.O=C(/C=C/c1ccc(F)c(Br)c1)NC1(C(=O)NCCc2c[nH]c3ccc(F)cc23)CCNCC1>>NCC(=O)N1CCC(NC(=O)/C=C/c2ccc(F)c(Br)c2)(C(=O)NCCc2c[nH]c3ccc(F)cc23)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110077154A1,CN(C)C(=O)Cl.Nc1ncccc1O>>CN(C)c1nc2ncccc2o1,CN(C)c1ccncc1,c1ccncc1,,,,test
US04737452,CCOC(=O)c1ccc(-n2cnnc2S)cc1>>O=C(O)c1ccc(-n2cnnc2S)cc1,,O,,[Na+].[OH-],,test
US20030078415A1,CN(C)OCCO[C@@H]1[C@H](O)[C@@H](CO[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)O[C@H]1n1cnc2c(NC(=O)c3ccccc3)ncnc21>>CN(C)OCCO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(NC(=O)c3ccccc3)ncnc21,,C1CCOC1,,,,test
US20130046013A1,CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCOC(CC)C(=O)N[C@@H](CC(C)C)C(=O)Nc1ccc(O)c(C(=O)OC)c1>>CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCOC(CC)C(=O)N[C@@H](CC(C)C)C(=O)Nc1ccc(O)c(C(=O)O)c1,,CO,,Cl,[Li+].[OH-],test
US20140256719A1,Clc1nc(Cl)c2c(-c3ccccc3)ccn2n1.NCc1ccccn1>>Clc1nc(NCc2ccccn2)c2c(-c3ccccc3)ccn2n1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20040210080A1,C=O.CCCCCC(=O)c1ccc(NC(=O)C(C)(C)C)c(F)c1>>C=C(CCCC)C(=O)c1ccc(NC(=O)C(C)(C)C)c(F)c1,,CO,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US05659059,CCCCCBr.Fc1cc(C2CC[SiH](Cl)CC2)ccc1-c1ccc(OC(F)(F)F)cc1>>CCCCC[Si@@H]1CC[C@@H](c2ccc(-c3ccc(OC(F)(F)F)cc3)c(F)c2)CC1,,C1CCOC1,,[Mg],,test
US06037361,BrCCc1ccccc1.O=C(O)C(F)C(F)C(=O)c1ccc2oc3ccccc3c2c1>>O=C(c1ccc2oc3ccccc3c2c1)C(F)C(F)(CCc1ccccc1)C(=O)O,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20120264735A1,CCOC(=O)Nc1cccc(C(F)c2nn(-c3ccc(Cl)cc3)ccc2=O)c1>>CCOC(=O)Nc1cccc(Cc2nn(-c3ccccc3)ccc2=O)c1,[Pd],CO,,CC(=O)N(C)C,,test
US20110257151A1,COCCNC(=O)c1cccc(C2Nc3ccc(C(=O)OC)cc3CC2(C)C)c1>>COCCNC(=O)c1cccc(C2Nc3ccc(C(=O)O)cc3CC2(C)C)c1,,CO,O,Cl,[Na+].[OH-],test
US05023341,CC1(C)CCNc2ccc(C#C[Si](C)(C)C)cc21>>C#Cc1ccc2c(c1)C(C)(C)CCN2,,CC(C)O,,[K+].[OH-],,test
US03931200,Nc1ccc(OCc2nc(Cl)ccc2Cl)cc1.O=C(Cl)Cl>>O=C=Nc1ccc(OCc2nc(Cl)ccc2Cl)cc1,,Cc1ccccc1,,,,test
US20030232832A1,C=C[Mg]Br.O=Cc1nn2ccc(Cl)c2c(=O)n1Cc1ccccc1>>C=CC(O)c1nn2ccc(Cl)c2c(=O)n1Cc1ccccc1,,C1CCOC1,,,,test
US20120157479A1,C=C[C@H]1CN(C(=O)OC(C)(C)C)C[C@@H]1O[Si](C)(C)C(C)(C)C>>CC[C@H]1CN(C(=O)OC(C)(C)C)C[C@@H]1O[Si](C)(C)C(C)(C)C,[Pd],CCO,,,,test
US20090181948A1,C1COCCN1.N#CC(C#N)=C1N(CCCBr)CCN1C1CCN(Cc2ccccc2)CC1>>N#CC(C#N)=C1N(CCCN2CCOCC2)CCN1C1CCN(Cc2ccccc2)CC1,,O,,C1COCCO1,,test
US05530130,Cc1ccccc1C.O=S(=O)(Cl)c1ccccc1>>Cc1ccc(S(=O)(=O)c2ccccc2)cc1C,Cl[Fe](Cl)Cl,,,Cl,,test
US20120258950A1,CSCCl.O=C(Cc1ccc(Cl)cc1)Nc1cncc(C(=O)c2c[nH]c3ncncc23)c1>>CSCn1cc(C(=O)c2cncc(NC(=O)Cc3ccc(Cl)cc3)c2)c2cncnc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20060194779A1,COC(=O)c1nc(C)n(-c2ccccc2)c1C>>Cc1nc(C(=O)O)c(C)n1-c1ccccc1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20080182847A1,COC(OC)N(C)C.Nc1nc(=O)n(C2CCC(O)C2)cc1F>>CN(C)C=Nc1nc(=O)n(C2CCC(O)C2)cc1F,,CN(C)C=O,,,,test
US05132451,CCOC(=O)CC1(C#N)CCCCC1>>N#CC1(CC(=O)O)CCCCC1,,CO,,O,[Na+].[OH-],test
US05929072,C=CCN1c2c(cccc2C(=O)OCC)CN(C(C)C)S1(=O)=O.O=[O+][O-]>>CCOC(=O)c1cccc2c1N(CC=O)S(=O)(=O)N(C(C)C)C2,,ClCCl,,CSC,,test
US20060025414A1,CN=C(SC)N1CCCCC1c1nnn(-c2cccc(Cl)c2)n1.NNC(=O)c1ccncc1>>Cn1c(-c2ccncc2)nnc1N1CCCCC1c1nnn(-c2cccc(Cl)c2)n1,,CCO,O,,,test
US04027027,Cc1ccccc1OCC(O)CN(CCOc1ccc(C(N)=O)cn1)Cc1ccccc1>>Cc1ccccc1OCC(O)CNCCOc1ccc(C(N)=O)cn1,[Pd],C1COCCO1,,[H][H],,test
US20040044203A1,C1COCCN1.O=Cc1cc(Br)c2nc(-c3c(NC[C@@H](O)c4cccc(Cl)c4)cc[nH]c3=O)[nH]c2c1>>O=c1[nH]ccc(NC[C@@H](O)c2cccc(Cl)c2)c1-c1nc2c(Br)cc(CN3CCOCC3)cc2[nH]1,,CO,,[BH3-]C#N.[Na+],,test
US20100004235A1,CCOC(=O)C(F)(F)F.Fc1ccccn1.NN>>FC(F)(F)c1n[nH]c2ncccc12,,C1CCOC1,,O,CC(C)[N-]C(C)C.[Li+],test
US20140213586A1,COc1ccc(N)cc1OC.O=C(c1c[nH]c2ccccc12)C(Cl)c1ccccc1>>COc1ccc(NC(C(=O)c2c[nH]c3ccccc23)c2ccccc2)cc1OC,,CN(C)C=O,,CCN(CC)CC,,test
US20100168418A1,CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)cc(OCc3ccccc3)c3ccccc32)CC1>>CC(C)(C)OC(=O)N(Cc1ccc2c(c1)OCCO2)C1CCN(CCn2c(=O)cc(O)c3ccccc32)CC1,[Pd],C1CCOC1,,CO,,test
US04081488,C=C(Cl)Cl.CC(C)C(=O)Cl>>CC(C)C(=O)C=C(Cl)Cl,,ClCCl,,,,test
US04179506,COc1ccccc1Oc1cccnc1Cl.Cl.c1ccncc1>>Cl.c1ccc2c(c1)Oc1cccnc1O2.c1ccncc1,,O,,Cl,c1ccncc1,test
US20060135566A1,Cc1cccc(-c2nc(-c3ccc(S(C)(=O)=O)cc3)sc2-c2ccnc(Sc3ccccc3)c2)c1.O=C(OO)c1cccc(Cl)c1>>Cc1cccc(-c2nc(-c3ccc(S(C)(=O)=O)cc3)sc2-c2ccnc(S(=O)(=O)c3ccccc3)c2)c1,,CN(C)C=O,,[Na+].[OH-],,test
US20120277217A1,CC(C)(C)OC(=O)NC1CCCCC1N.CCOC(=O)Cc1ccc(N)cc1Cl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CCOC(=O)Cc1ccc(NC(=O)NC2CCCCC2NC(=O)OC(C)(C)C)cc1Cl,,ClCCl,,CCN(CC)CC,,test
US20130211075A1,COC(=O)C1(c2ncc(Br)cc2C)CCOCC1>>Cc1cc(Br)cnc1C1(C(=O)O)CCOCC1,,C1CCOC1,CO,[Na+].[OH-],,test
US20120165306A1,CS(=O)(=O)Cl.N[C@@H]1CC[C@H](C(=O)Nc2cc(-c3cncc(NCC4CCOCC4)n3)c(Cl)cn2)C1>>CS(=O)(=O)N[C@@H]1CC[C@H](C(=O)Nc2cc(-c3cncc(NCC4CCOCC4)n3)c(Cl)cn2)C1,,ClCCl,O,CCN(CC)CC,,test
US20040023964A1,O=[N+]([O-])c1ccc(Cl)c(-c2cccnc2)c1>>Nc1ccc(Cl)c(-c2cccnc2)c1,,C1COCCO1,CCO,Cl[Sn]Cl,,test
US20100137313A1,CC(=O)Nc1nc(C)c(S(N)(=O)=O)s1.COc1cc(Nc2ncc(-c3cnc(OC)c(C(=O)O)c3)c(-n3nc(C(F)(F)F)cc3C)n2)cc(OC)c1>>COc1cc(Nc2ncc(-c3cnc(OC)c(C(=O)NS(=O)(=O)c4sc(NC(C)=O)nc4C)c3)c(-n3nc(C(F)(F)F)cc3C)n2)cc(OC)c1,CN(C)c1ccncc1,ClCCl,ClCCl,CCN(CC)CC,C[n+]1ccccc1Cl.[I-],test
US04786649,CS(=O)(=O)Cl.OCC1CN(Cc2ccccc2)CC1O>>CS(=O)(=O)CC1CN(Cc2ccccc2)CC1O,,ClCCl,,CCN(CC)CC,,test
US20100216836A1,CC(=O)c1cc(F)ccc1O.Cc1ccc(S(=O)(=O)OC[C@H]2CO2)cc1>>O=CC[C@@]1(OCC2CO2)C=C(F)C=CC1,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080021032A1,O=[N+]([O-])c1cc[nH]n1.OCC1CC1>>O=[N+]([O-])c1ccn(CC2CC2)n1,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140350019A1,CCOC(=O)CBr.Oc1ccc(Cl)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1F>>CCOC(=O)COc1ccc(Cl)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1F,,CCC(C)=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20160090374A1,CN[C@H]1CCNC1.Clc1nc(Cl)c2ccccc2n1>>CN[C@H]1CCN(c2nc(Cl)nc3ccccc23)C1,,CCO,ClC(Cl)Cl,,,test
US04968809,CCOC(=O)C1c2ccccc2-c2ccccc21.NS(=O)(=O)CBr.NS(=O)(=O)CI>>CCOC(=O)C1(C)c2ccccc2-c2cccc(S(N)(=O)=O)c21,,CN(C)C=O,O,Cl,O=C([O-])[O-].[K+].[K+],test
US20080194640A1,CC(C)c1ccc(NC(=O)OC(C)(C)C)cn1>>CC(C)c1ccc(N)cn1,,CCOCC,,C1COCCO1,Cl,test
US05104867,CCN1C[C@@H](SCc2ccc(OC)cc2)C[C@H]1C(N)=O.COS(=O)(=O)F>>CC[N+]1(C)C[C@@H](SCc2ccc(OC)cc2)C[C@H]1C(N)=O.O=S(=O)([O-])F,,ClCCl,,,,test
US05883102,N#Cc1ccccc1N.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>N#Cc1ccccc1NC(=O)C(F)(F)F,,ClCCl,,,,test
US20140235616A1,CCCC[Sn](CCCC)(CCCC)c1ccccn1.O=c1c2c(c3cc(F)c(Cl)cc3n1CC(F)(F)F)NN(C1CCCCO1)C2>>O=c1c2c(c3cc(F)c(-c4ccccn4)cc3n1CC(F)(F)F)NN(C1CCCCO1)C2,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20090118275A1,CS(=O)(=O)c1nc2nc(Cl)nc(N3CCOCC3)c2s1.Nc1ccccc1>>Clc1nc(N2CCOCC2)c2sc(Nc3ccccc3)nc2n1,,Cc1ccccc1,,,,test
US05753664,CCOC(=O)c1ncn(Cc2ccc(C(=O)c3ccc(Cl)cc3)cc2)c1C=O.CNN>>Cn1ncc2c(ncn2Cc2ccc(C(=O)c3ccc(Cl)cc3)cc2)c1=O,,CCO,O,O=S(=O)(O)O,,test
US20090286778A1,CC(C)(C)OC(=O)Nc1cccc(COS(C)(=O)=O)c1.O=[N+]([O-])c1cccc(CS)c1>>CC(C)(C)OC(=O)Nc1cccc(CSCc2cccc([N+](=O)[O-])c2)c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US05563162,CCOC(=O)C=Cc1ccc(NC(=O)CCCBr)cc1>>CCOC(=O)C=Cc1ccc(N2CCCC2=O)cc1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20040132726A1,COC(=O)c1cc(-c2cc(C)ccc2F)on1.C[Mg]I>>CC(=O)c1cc(-c2cc(C)ccc2F)on1,,Cc1ccccc1,,C1CCOC1,CCN(CC)CC,test
US20140128371A1,COC(=O)c1cc(C(C)=NO)c(F)c(Cl)c1N1C[C@H](C)O[C@H](C)C1>>Cc1noc2c(Cl)c(N3C[C@H](C)O[C@H](C)C3)c(C(=O)O)cc12,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130210809A1,CCOC(=O)c1cn(Cc2ccc(OC)cc2)nc1Br>>COc1ccc(Cn2cc(C(=O)O)c(Br)n2)cc1,,CO,,Cl,[Na+].[OH-],test
US20150087646A1,Cc1ccc(NNC(=O)OC(C)(C)C)cc1Cl.O=C=NC(=O)c1cc(CNC(=O)C(F)(F)F)c(F)cc1Cl>>Cc1ccc(-n2nc(-c3cc(CNC(=O)C(F)(F)F)c(F)cc3Cl)[nH]c2=O)cc1Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US05047420,CCCOc1c(OC)cc(CC#N)cc1SC.CCOC(=O)OCC>>CCCOc1c(OC)cc(C(C#N)C(=O)OCC)cc1SC,,Cc1ccccc1,,,,test
US20100004239A1,C1CCNCC1.CCN(CCN1CCc2[nH]c(C=O)c(C)c2C1=O)C(=O)OC(C)(C)C.O=C1Cc2cc(F)ccc2N1>>CCN(CCN1CCc2[nH]c(C=C3C(=O)Cc4ccc(F)cc43)c(C)c2C1=O)C(=O)OC(C)(C)C,,CCO,,,,test
US20060069134A1,CCOC(=O)C1CSC(c2ccccc2)=N1>>O=C(O)C1CSC(c2ccccc2)=N1,,CO,,[Na+].[OH-],,test
US20110034455A1,O=C1C2CC3CC1CC(C(=O)O)(C3)C2>>O=C(O)C12CC3CC(C1)C(O)C(C3)C2,,CO,,[BH4-].[Na+],,test
US20060019985A1,C=CC(=O)O.CC(C)(C)OC(=O)N1CCC(NCc2ccccc2)CC1>>C=CC(=O)N(Cc1ccccc1)C1CCN(C(=O)OC(C)(C)C)CC1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US05352381,C#Cc1ccc(CCC)cc1.CCCCCSc1ccc(I)cc1>>C(#Cc1ccccc1)c1ccccc1,[Cu]I,CCNCC,,,,test
US20150299143A1,COC(=O)c1cn(CCN2Cc3ccccc3C2=O)nn1>>O=C(O)c1cn(CCN2Cc3ccccc3C2=O)nn1,,CO,,[Na+].[OH-],,test
US20090286882A1,CCOC(=O)CC1(CCC(/C=C/c2ccccc2OCc2ccc(OC(F)(F)F)cc2)Cc2ccc(C(=O)O)cc2)CC1>>O=C(O)CC1(CCC(/C=C/c2ccccc2OCc2ccc(OC(F)(F)F)cc2)Cc2ccc(C(=O)O)cc2)CC1,,C1CCOC1,O,[Li+].[OH-],,test
US20080188531A1,CC(C)(C)OC(=O)NCC/C(N)=N/OC(=O)C(C)(C)C>>CC(C)(C)OC(=O)NCCc1noc(C(C)(C)C)n1,,C1CCOC1,,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20160024049A1,OC1CCN(Cc2ccccc2)C1.Oc1cccnc1Cl>>Clc1ncccc1OC1CCN(Cc2ccccc2)C1,,C1CCOC1,O,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040116685A1,Br[Mg]c1ccccc1.C=CC=CCCOc1ccc(C(=O)c2ccc(OCCC=CC=C)cc2)cc1>>C=CC=CCCOc1ccc(C(O)(c2ccccc2)c2ccc(OCCC=CC=C)cc2)cc1,,C1CCOC1,,,,test
US20160272617A1,Cc1cc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc3c(=O)[nH][nH]c3c2)cc1.Cl>>Cc1cc(C(=O)NC2CCNCC2)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc3c(=O)[nH][nH]c3c2)cc1.Cl,,C1COCCO1,,,,test
US20160024091A1,CC(C)(C)OC(=O)N1CCC2(CC1)CC1(CC1)NC2=O>>CC1(C)CC2(CCN(C(=O)OC(C)(C)C)CC2)C(=O)N1,O=[Pt]=O,CC(=O)O,CCOC(C)=O,,,test
US20120202834A1,CCOC(=O)c1ccc(I)cc1.O=C(Cl)C1CC(F)(F)C1>>CCOC(=O)c1ccc(C(=O)C2CC(F)(F)C2)cc1,I[Cu]I,C1CCOC1,Cl,,,test
US20120010191A1,Cn1cc(Br)cc(Nc2ccc3c(c2)CCN(C(=O)OC(C)(C)C)C3)c1=O>>Cn1cc(Br)cc(Nc2ccc3c(c2)CCNC3)c1=O,,C1COCCO1,,Cl,,test
US20140330009A1,CC(=O)N1CCc2[nH]nc(-c3cccc(C#N)c3)c2C1.Fc1ccc(CBr)c(F)c1>>CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2Cc2ccc(F)cc2F)C1,,CC#N,,O,O=C([O-])[O-].[K+].[K+],test
US20110028445A1,CC1(C)[C@H]2Cc3c(O)cccc3[C@]1(C)CCN2C(=O)n1ccnc1.CI>>C[n+]1ccn(C(=O)N2CC[C@@]3(C)c4cccc(O)c4C[C@@H]2C3(C)C)c1.[I-],,CC#N,,,,test
US20060004043A1,CCOC(=O)CN1[C@@H](C)CCC[C@H]1C.NN>>C[C@H]1CCC[C@@H](C)N1CC(=O)NN,,CCO,,,,test
US20100125081A1,CC(C)(C)S(=O)N=C(c1cccc(Br)c1)c1cccnc1C#N.COc1c(C)cc(Br)nc1C>>COc1c(C)cc(C2(c3cccc(Br)c3)N=C(N)c3ncccc32)nc1C,,C1CCOC1,ClCCl,Cl,[Li]CCCC,test
US05695684,CCCCCc1ccc(-c2ccc3cc(OC)ccc3n2)cc1>>CCCCCc1ccc(-c2ccc3cc(O)ccc3n2)cc1,,CCCCCC,,Br,CC(=O)O,test
US20030171418A1,COC1c2c(ccc3cnn(C[C@H](C)NC(=O)OCc4ccccc4)c23)OCC1O>>COC1c2c(ccc3cnn(C[C@H](C)N)c23)OCC1O,,CO,,O=C(O)C(F)(F)F,,test
US20140031342A1,CCOC(=O)c1ccc(Cl)nc1.Oc1ccc(OC(F)(F)F)cc1>>CCOC(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)nc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080139580A1,CCCc1c(Cn2ccnc2-c2ncccc2F)ncnc1NN.O=C(OC(=O)C(F)F)C(F)F>>CCCc1c(Cn2ccnc2-c2ncccc2F)ncn2c(C(F)F)nnc12,,ClCCl,,O=C([O-])O.[Na+],,test
US07074801B1,CC(C)(C)OC(=O)N1CCC(O)CC1.CSc1ccc(O)c(F)c1>>CSc1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)c(F)c1,,C1CCOC1,O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120046267A1,Nc1nccc2c(Cl)c(Cl)oc12.O=C1CCC(=O)N1I>>Nc1ncc(I)c2c(Cl)c(Cl)oc12,,CC#N,,,,test
US05104888,CCI.Cc1c(C)c2c(c(C)c1O)CCC(C)(COc1ccc(CC3SC(=O)NC3=O)cc1)O2>>CCN1C(=O)SC(Cc2ccc(OCC3(C)CCc4c(C)c(O)c(C)c(C)c4O3)cc2)C1=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05391817,CC1(C)CCC(C)(C)c2cc(CCl)ccc21.O=Cc1cccc(O)c1O>>CC1(C)CCC(C)(C)c2cc(COc3c(O)cccc3C=O)ccc21,,CS(C)=O,,[H-].[Na+],,test
US20080305956A1,CI.O=C(O)c1ccc(C(F)(F)F)c(F)c1>>Cc1c(C(=O)O)ccc(C(F)(F)F)c1F,,C1CCOC1,,Cl,[Li]CCCC,test
US04334066,C1COCCN1.C=O.CCOC1C=CC(=O)C(C(C)C)O1>>CCOC1C=C(CN2CCOCC2)C(=O)C(C(C)C)O1,,CO,,,,test
US20060089392A1,CN(C)C=O.O=C(O)c1cc(I)ccc1[N+](=O)[O-]>>CN(C)C(=O)c1cc(I)ccc1[N+](=O)[O-],,ClC(Cl)Cl,,O=C(Cl)C(=O)Cl,,test
US20120010191A1,CC(=O)OCc1c(-c2cc(Nc3ccn(CCN(C)C(=O)OC(C)(C)C)n3)c(=O)n(C)c2)cccc1N1CCn2c(cc3c2CCCC3)C1=O>>CN(CCn1ccc(Nc2cc(-c3cccc(N4CCn5c(cc6c5CCCC6)C4=O)c3CO)cn(C)c2=O)n1)C(=O)OC(C)(C)C,,C1CCOC1,CC(C)O,O,[Li+].[OH-],test
US20120021907A1,CCc1ccc(O)cc1C1C(=O)C(C)(C)OC(C)(C)C1=O.O=[N+]([O-])c1ccc(F)c(F)c1>>CCc1ccc(Oc2ccc([N+](=O)[O-])cc2F)cc1C1C(=O)C(C)(C)OC(C)(C)C1=O,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US06251912B1,CN1CCN(CC#CC(=O)O)CC1.Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1>>CN1CCN(CC#CC(=O)Nc2ccc3ncnc(Nc4cccc(Br)c4)c3c2)CC1,,C1CCOC1,c1ccncc1,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20160176882A1,BrCCCOc1cncc(Br)c1.CS(=O)O[Na]>>CS(=O)(=O)CCCOc1cncc(Br)c1,,O,,CS(C)=O,,test
US06506901B2,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.Oc1ccc(OCc2ccccc2)cc1>>CC(C)(C)[Si](Oc1ccc(OCc2ccccc2)cc1)(c1ccccc1)c1ccccc1,,ClCCl,,c1c[nH]cn1,,test
US05409936,CCOC(=O)C=O.CCc1nc(CCN)cn1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>CCOC(=O)C1NCCc2nc(CC)n(Cc3ccc(-c4ccccc4-c4nnnn4C(c4ccccc4)(c4ccccc4)c4ccccc4)cc3)c21,,C1CCOC1,,O,,test
US20110288067A1,CC(C)(C)OC(=O)N[C@@H](COS(C)(=O)=O)C(C)(C)C.[C-]#N>>CC(C)(C)OC(=O)N[C@@H](CC#N)C(C)(C)C,,CN(C)C=O,,CCOC(C)=O,O,test
US20110207747A1,COc1ccc(CN)cc1OC.O=C(O)c1cc(Br)ccc1I>>COc1ccc(CNC(=O)c2cc(Br)ccc2I)cc1OC,,ClCCl,,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US05364866,Cc1ccc2c(c1)C(=O)OC2=O.NCCN1CCC(c2noc3cc(F)ccc23)CC1>>Cc1ccc2c(c1)C(=O)N(CCN1CCC(c3noc4cc(F)ccc34)CC1)C2=O,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20090082359A1,C1CCNC1.ClCCCn1ncc2cc(Br)ccc21>>Brc1ccc2c(cnn2CCCN2CCCC2)c1,,CCOC(C)=O,CN(C)C=O,[I-].[K+],,test
US08618107B2,CN1CCn2nc(Nc3cc(Cl)nn(COCC[Si](C)(C)C)c3=O)cc2C1.Cc1c(B2OC(C)(C)C(C)(C)O2)cccc1N1CCc2c(n(COCC[Si](C)(C)C)c3ccccc23)C1=O>>Cc1c(-c2cc(Nc3cc4n(n3)CCN(C)C4)c(=O)n(COCC[Si](C)(C)C)n2)cccc1N1CCc2c(n(COCC[Si](C)(C)C)c3ccccc23)C1=O,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20130345212A1,COC(=O)c1cc(I)c(Cl)cc1N.O=C(O)CS(=O)(=O)c1ccccc1>>COC(=O)c1cc(I)c(Cl)cc1NC(=O)CS(=O)(=O)c1ccccc1,,CN(C)C=O,ClCCl,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20070032478A1,CN1CCN(c2ccc(N)cc2)CC1.Cc1cc(C(=O)Nc2ccc(C(=O)c3ccc4c(c3)NC(=O)C4=CO)cc2)n(C)n1>>Cc1cc(C(=O)Nc2ccc(C(=O)c3ccc4c(c3)NC(=O)C4=CNc3ccc(N4CCN(C)CC4)cc3)cc2)n(C)n1,,C1CCOC1,,,,test
US06046201,CCN1CCNCC1.NC(=O)c1ccc(Cl)nc1>>CCN1CCN(c2ccc(C(N)=O)cn2)CC1,,CCOC(C)=O,,,,test
US20090137499A1,BrCc1ccccc1.CCc1ccc(Cc2ccc(COC(C)=O)cc2O)cc1>>CCc1ccc(Cc2ccc(COC(C)=O)cc2OCc2ccccc2)cc1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US04681933,CCc1cn([C@H]2C[C@H](I)[C@@H](CO)O2)c(=O)[nH]c1=O>>CCc1cn([C@H]2CC[C@@H](CO)O2)c(=O)[nH]c1=O,[Pd],CO,,CCN(CC)CC,[H][H],test
US07169926B1,CCn1ccc(N)c(N)c1=O.O=C(NC1CCCC(C(=O)O)C1)OCc1ccccc1>>CCn1ccc2nc(C3CCCC(NC(=O)OCc4ccccc4)C3)[nH]c2c1=O,,CN(C)C=O,O,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20080188528A1,Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](N)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2.O=C(O)c1cccn(Cc2ccccc2Br)c1=O>>Cc1c(C)c(S(=O)(=O)NC(=N)NCCC[C@H](NC(=O)c2cccn(Cc3ccccc3Br)c2=O)C(=O)OC(C)(C)C)c(C)c2c1OC(C)(C)CC2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030144297A1,CCOC(C)=O.CO.COC(=O)c1nc(N[C@@H]2c3ccccc3C[C@@H]2O)c(Br)nc1-c1ccc(Cl)cc1Cl>>CCOC(=O)c1nc(N[C@@H]2c3ccccc3C[C@@H]2O)c(OC)nc1-c1ccc(Cl)cc1Cl,,CCOC(C)=O,,C[O-].[Na+],,test
US06329027B1,CCCC[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](CI)CC2)CC1.Cc1ccc(-c2ccc(O)c(F)c2F)c(Cl)c1F>>CCCC[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](COc3ccc(-c4ccc(C)c(F)c4Cl)c(F)c3F)CC2)CC1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20080221335A1,CN(C)C=CC(=O)c1cccc(P(c2ccccc2)c2ccccc2)c1.NN>>c1ccc(P(c2ccccc2)c2cccc(-c3cc[nH]n3)c2)cc1,,CCO,,O,,test
US20090137581A1,Clc1ncnc2nc[nH]c12.NCc1cc2cccc(Cl)c2nc1-c1cccc(F)c1>>Fc1cccc(-c2nc3c(Cl)cccc3cc2CNc2ncnc3[nH]cnc23)c1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US05221673,COc1ccc(N2CCOCC2C=O)cc1OC.S=P12SP3(=S)SP(=S)(S1)SP(=S)(S2)S3>>COc1ccc(N2CCOCC2C=S)cc1OC,,c1ccncc1,,,,test
US05013849,CC(=O)C=Cc1ccccc1.Cc1ccc(C=O)cc1>>Cc1ccc(C=CC(=O)C=Cc2ccccc2)cc1,,CCO,O,[Na+].[OH-],,test
US05972972,Nc1n[nH]c(SCc2cccc(Oc3ccc(F)cc3)c2)c1-c1ccccn1.O=S(=O)(Cl)c1c(Cl)cccc1Cl>>O=S(=O)(Nc1n[nH]c(SCc2cccc(Oc3ccc(F)cc3)c2)c1-c1ccccn1)c1c(Cl)cccc1Cl,,c1ccncc1,,O,,test
US20080004274A1,CCCCCCCN1C(=O)C(=O)c2cc(SCCc3ccc(C(=O)O)cc3)ccc21.NNC(=O)Nc1ccccc1Cl>>CCCCCCCN1C(=O)C(=NNC(=O)Nc2ccccc2Cl)c2cc(SCCc3ccc(C(=O)O)cc3)ccc21,,CC(=O)O,CO,Cl,,test
US20060160864A1,CCOC(=O)C(CC)P(=O)(OCC)OCC.O=Cc1cc(Br)ccc1N1CCCC1>>CCOC(=O)/C(=C/c1cc(Br)ccc1N1CCCC1)CC,,Cc1ccccc1,,O,[H-].[Na+],test
US20060041144A1,C#CCO.COc1ccc(-c2ncccc2NC(=O)C(OS(C)(=O)=O)c2ccc(Cl)cc2)cc1OC>>C#CCOC(C(=O)Nc1cccnc1-c1ccc(OC)c(OC)c1)c1ccc(Cl)cc1,,O,,,,test
US04044150,CS(=O)(=O)Nc1ccc(C(O)CNCCOc2ccccc2)cc1.[Na]>>CS(=O)(=O)Nc1ccc(C(O)CNCCOc2ccccc2)cc1.[Na],,CCOCC,,CO,C[O-].[Na+],test
US04603012,CC(C)(C=O)NC(=O)OC(C)(C)C.CC1(C)CCC(C)(C)C1CBr>>CC(C)(C=CC1C(C)(C)CCC1(C)C)NC(=O)OC(C)(C)C,,CCOCC,,[Mg],,test
US04704459,CCOC(=O)CC(=O)c1cc(F)c(OC)nc1Nc1ccc(F)cc1F.COC(OC)N(C)C>>CCOC(=O)c1cn(-c2ccc(F)cc2F)c2nc(OC)c(F)cc2c1=O,,c1ccccc1,,CCOCC,,test
US20030176430A1,C1CCOC1.O=C1COC[C@@H]([N-]Cc2ccccc2)N1Cc1ccccc1>>c1ccc(CNCC2COCCN2Cc2ccccc2)cc1,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20120142665A1,Brc1ccn2nc(Br)nc2c1.CNC1CC1>>CN(c1nc2cc(Br)ccn2n1)C1CC1,,CCOC(C)=O,,,,test
US20060122168A1,CC(C)(Oc1ccc(F)cc1[N+](=O)[O-])C(C(=O)O)N(Cc1ccccc1)Cc1ccccc1>>CC(C)(Oc1ccc(F)cc1N)C(C(=O)O)N(Cc1ccccc1)Cc1ccccc1,[Ni],CO,,,,test
US20090105259A1,COC(=O)[C@@H](CCCN)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(F)cc1Cl>>COC(=O)[C@@H](CCCN)NS(=O)(=O)c1ccc(F)cc1Cl,,C1COCCO1,ClCCl,Cl,,test
US20130203776A1,CN(CCCCl)C(=O)c1cnn2ccc(N3CCC[C@@H]3c3cc(F)c[nH]c3=O)nc12>>CN1CCCOc2ncc(F)cc2[C@H]2CCCN2c2ccn3ncc(c3n2)C1=O,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04200578,C#CCN.CSC(=NCCSCc1csc(NC(=N)N)n1)NC#N>>C#CCNC(=NCCSCc1csc(NC(=N)N)n1)NC#N,,CO,,,,test
US20120264749A1,Cc1noc(C2CN(Cc3ccccc3)CC3(CCN(C(=O)c4ccc(OC(C)C)c(C)c4)CC3)O2)n1.ClCCCl>>Cc1noc(C2CNCC3(CCN(C(=O)c4ccc(OC(C)C)c(C)c4)CC3)O2)n1.Cl,,ClCCCl,,CC(Cl)OC(=O)Cl,,test
US20070179191A1,CCCCc1nc(-c2ccc(C(F)(F)F)cc2)sc1CO.N#Cc1ccc(CBr)cc1F>>CCCCc1nc(-c2ccc(C(F)(F)F)cc2)sc1COCc1ccc(C#N)c(F)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20120165310A1,NC1CC(COC(=O)c2ccccc2)C1.O=C(Cl)OCc1ccccc1>>O=C(N[C@@H]1C[C@H](COC(=O)c2ccccc2)C1)OCc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20120220624A1,O=c1cc(Cc2ccc3ccccc3c2)[nH]c2n[nH]c([C@@H]3C[C@@H](O)C3)c12>>O=C1CC(c2[nH]nc3[nH]c(Cc4ccc5ccccc5c4)cc(=O)c23)C1,,C1CCOC1,CN(C)C=O,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20050192302A1,Cc1cnc(C2(O)CCC3(CC2)OCCO3)s1>>Cc1cnc(C2(O)CCC(=O)CC2)s1,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20140296252A1,Cc1nc(-n2nc(C3(C(F)(F)F)CCC3)[nH]c2=O)ccc1Oc1ccnc(Cl)c1.Cn1cc(B2OC(C)(C)C(C)(C)O2)cn1>>Cc1nc(-n2nc(C3(C(F)(F)F)CCC3)[nH]c2=O)ccc1Oc1ccnc(-c2cnn(C)c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05488149,CC(C)(C)[Si](C)(C)Cl.CC(O)C(Cc1ccc(Cl)c(Cl)c1)C(=O)OC(C)(C)C>>CC(O[Si](C)(C)C(C)(C)C)C(CO)Cc1ccc(Cl)c(Cl)c1,,CCOCC,CN(C)C=O,c1c[nH]cn1,,test
US05922724,O=[N+]([O-])c1cccc(I)c1.c1cn[nH]c1>>O=[N+]([O-])c1cccc(-n2cccn2)c1,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],,test
US20140248240A1,CC(C)(C)OC(=O)NCCCCC1CCN(C(=O)c2ccccc2)C1>>NCCCCC1CCN(C(=O)c2ccccc2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04007176,CCOC(=O)CC1=COCCS1>>O=C(O)CC1=COCCS1,,CCO,O,[Na+].[OH-],,test
US20110112103A1,Brc1ccc(Br)cc1.CON(C)C(=O)c1ccc(C)nc1>>Cc1ccc(C(=O)c2ccc(Br)cc2)cn1,,C1CCOC1,O,CCCCCC,[Li]CCCC,test
US20150158848A1,CCN1C(=O)N(C(=O)OC(C)(C)C)C2CCCC21>>CCN1C(=O)NC2CCCC21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100144707A1,CC(C)(C)OC(=O)n1ncc2cc(Nc3nc(-c4cccc(O)c4)nc4ccccc34)ccc21.CC(C)NC(=O)CBr>>CC(C)NC(=O)COc1cccc(-c2nc(Nc3ccc4c(cnn4C(=O)OC(C)(C)C)c3)c3ccccc3n2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04377522,CN1C(=O)C(C)(C)N=C(c2ccccc2Cl)c2cc(N)ccc21.ClCl>>CN1C(=O)C(C)(C)N=C(c2ccccc2Cl)c2c1ccc(N)c2Cl,,CC(=O)O,,,,test
US20080146800A1,CN1CCN(C(=O)Cl)CC1.O=C1c2nccnc2C(O)N1c1ccc(Cl)cn1>>CN1CCN(C(=O)OC2c3nccnc3C(=O)N2c2ccc(Cl)cn2)CC1,,CCN(CC)CC,,Cl,,test
US20080108624A1,CC(C)(C)OC(=O)N1CCC(CC2CCNCC2)CC1.CCI>>CCN1CCC(CC2CCN(C(=O)OC(C)(C)C)CC2)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20100081692A1,C=C(CC)CO.COC(=O)Cc1ccccc1O>>C=C(CC)COc1ccccc1CC(=O)OC,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US04408052,CCCCCCCCCCCCCCCCCCN=C=O.OCCO>>CCCCCCCCCCCCCCCCCCNC(=O)OCCO,,c1ccncc1,,,,test
US20150246902A1,NO.O=C(c1ccccc1)c1cc(Br)ccc1O>>O/N=C(\c1ccccc1)c1cc(Br)ccc1O,,CCO,c1ccncc1,CCOC(C)=O,Cl,test
US05646273,C=C(C)CC(O)C(C)C.N#Cc1cccc([N+](=O)[O-])c1C#N>>C=C(C)CC(Oc1cccc(C#N)c1C#N)C(C)C,,Cc1ccccc1,O,CN(C)C=O,[H-].[Na+],test
US20150094296A1,O=C(O)C1(c2ccc([N+](=O)[O-])cc2)CC1>>Nc1ccc(C2(C(=O)O)CC2)cc1,[Pd],CCO,,,,test
US20040249173A1,C=C1C=Cc2cc(C(=O)O)ccc2OC1.Nc1ccccc1>>C=C1C=Cc2cc(C(=O)Nc3ccccc3)ccc2OC1,,CO,,COc1nc(OC)nc([N+]2(C)CCOCC2)n1.[Cl-],,test
US20080153812A1,CCN1CCN(c2ncc(C(=O)OC)cn2)CC1C.COc1cc(CCc2cc(N)[nH]n2)cc(OC)c1>>CCN1CCN(c2ncc(C(=O)Nc3cc(CCc4cc(OC)cc(OC)c4)n[nH]3)cn2)CC1C,,Cc1ccccc1,,C[Al](C)C,,test
US20060116400A1,O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(-c2ccc(C3=NOC(CO)C3)[n+]([O-])c2)c(F)c1.OC(c1ccccc1)C1CC(c2ccc(Br)cn2)=NO1>>O=C1O[C@@H](Cn2ccnn2)CN1c1ccc(-c2ccc(C3=NOC(C(O)c4ccccc4)C3)nc2)c(F)c1,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20160002195A1,CCCCC(F)(F)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21.CCCCC(F)(F)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21.CCN(CC)CC.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.O=[N+]([O-])[O-].[NH3+]CCO[N+](=O)[O-]>>CCCCC(F)(F)c1cc(OC(=O)NCCO[N+](=O)[O-])c2c(c1)OC(C)(C)[C@@H]1CC=C(C)C[C@@H]21.CCCCC(F)(F)c1cc(OC(=O)NCCO[N+](=O)[O-])c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21,,ClCCl,O,,,test
US20040006141A1,CCCCC(Cc1ccc(OCCNC(=O)c2ccc(-c3ccc(C=O)cc3)cc2)cc1)C(=O)O>>CCCCC(Cc1ccc(OCCNC(=O)c2ccc(-c3ccc(CO)cc3)cc2)cc1)C(=O)O,,CCO,,CC(=O)O,[BH4-].[Na+],test
US05665718,CCOC(=O)c1ncn2c1[C@@H]1CCN1C(=O)c1sccc1-2>>O=C(O)c1ncn2c1[C@@H]1CCN1C(=O)c1sccc1-2,,CCO,O,[Na+].[OH-],,test
US20140121187A1,COc1cc(C(C)C)ccc1C1(O)C(=O)c2ccc([N+](=O)[O-])c(NC(C)=O)c2C1=O>>COc1cc(C(C)C)ccc1C1(O)C(=O)c2ccc(N)c(NC(C)=O)c2C1=O,[Fe],CCO,,Cl,O,test
US20030191323A1,CCCCCCCCCC(=O)Cl.NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCc2ccc([N+](=O)[O-])cc2)c1>>CCCCCCCCCC(=O)NS(=O)(=O)c1ccccc1NC(=O)c1cccc(OCc2ccc([N+](=O)[O-])cc2)c1,CN(C)c1ccncc1,C1CCOC1,,,,test
US04070464,CC(C)(C)c1cc(I)c(O)c(CN)c1.CN1CCC(=O)CC1>>CN1CCC2(CC1)NCc1cc(C(C)(C)C)cc(I)c1O2,,c1ccccc1,,CC(=O)O,,test
US20120065195A1,CC1CCc2ccc(Br)cc2C12NC(=O)NC2=O.CI>>CC1CCc2ccc(Br)cc2C12NC(=O)N(C)C2=O,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20130018044A1,CCOC(=O)C(Cc1cccc(OCc2ccccc2)c1)NC(=O)NCc1ccc(N)cc1>>CCOC(=O)C(Cc1cccc(O)c1)NC(=O)NCc1ccc(N)cc1,[Pd],CO,,,,test
US20110218192A1,C[Si](C)(C)N=C=N[Si](C)(C)C.O=C1CC(C2CCOCC2)Oc2ccc(Br)cc21>>N#C/N=C1\CC(C2CCOCC2)Oc2ccc(Br)cc21,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20150087639A1,COC(=O)/C=C(/C)N.O=C(Cl)CCCOc1cccc(F)c1>>COC(=O)/C=C(/C)NC(=O)CCCOc1cccc(F)c1,,ClCCl,,c1ccncc1,,test
US05725798,CCCCCCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1>>CCCCCCCCCCOc1ccc(-c2ccc(CO)cc2)cc1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04001199,COC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N[N+](=O)[O-])NC(=O)CCNC(=O)OCc1ccccc1>>N=C(NCCC[C@H](NC(=O)CCNC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O)N[N+](=O)[O-],,CC(C)=O,,[Na+].[OH-],,test
US06204277B1,CC(N)=O.COC(=O)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O>>COC(=O)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)NC(C)=O,,O,,O=S(Cl)Cl,,test
US20100113465A1,FC(F)(F)c1ccc(Oc2cccc(C3CC4(CCNCC4)C3)c2)nc1.O=C(Nc1cccnn1)Oc1ccccc1>>O=C(Nc1cccnn1)N1CCC2(CC1)CC(c1cccc(Oc3ccc(C(F)(F)F)cn3)c1)C2,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20150018341A1,CCC(=C(c1ccc(O)cc1)c1ccc(OCCCl)cc1)c1ccc2oc(Cl)cc2c1.CN1CCNCC1>>CCC(=C(c1ccc(O)cc1)c1ccc(OCCN2CCN(C)CC2)cc1)c1ccc2oc(Cl)cc2c1,,CO,,,,test
US20050227980A1,ClCc1ccccc1.O=C1COCCN1>>O=C1COCCN1Cc1ccccc1,,CN(C)C=O,,Cl,[H-].[Na+],test
US20090298949A1,CC(C)(C)c1cc(O)c(C=O)c(C(C)(C)C)c1.CN>>CNCc1c(O)cc(C(C)(C)C)cc1C(C)(C)C,,CC(=O)O,ClCCCl,O=C([O-])O.[Na+],,test
US05629326,COc1cc(C(C)=O)ccc1OCCCCl.Clc1ccc2c(C3CCNCC3)noc2c1>>COc1cc(C(C)=O)ccc1OCCCN1CCC(c2noc3cc(Cl)ccc23)CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20050131017A1,CCCC[Sn](Cl)(CCCC)CCCC.Cc1ccc(Br)cn1>>CCCC[Sn](CCCC)(CCCC)c1ccc(C)nc1,,CCOCC,,[Li]CCCC,,test
US20110201605A1,CO.Fc1ccc(-c2cccn3nc(NC4CCN(c5ccnc(Cl)n5)CC4)nc23)c(Cl)c1>>COc1nccc(N2CCC(Nc3nc4c(-c5ccc(F)cc5Cl)cccn4n3)CC2)n1,,CO,,C[O-].[Na+],,test
US20130267510A1,CC12COc3cccc(Oc4ccc(NC(=O)C(C)(C)N(C(=O)[O-])C(C)(C)C)cn4)c3C1C2>>CC(C)(N)C(=O)Nc1ccc(Oc2cccc3c2C2CC2(C)CO3)nc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04748165,CCCN=C(N)Nc1ccnc(CCCCC(=N)N)n1.CCOC(=O)C(C=O)CC>>CCCN=C(N)Nc1ccnc(CCCCc2ncc(CC)c(O)n2)n1,,CO,,Cl,[Na],test
US20150031708A1,COc1ncc(-c2nc(N)ccc2C)cc1C.O=C(O)C1(c2ccc3c(c2)OCCO3)CC1>>COc1ncc(-c2nc(NC(=O)C3(c4ccc5c(c4)OCCO5)CC3)ccc2C)cc1C,CN(C)C=O,ClCCl,,CCN(CC)CC,O=S(Cl)Cl,test
US04839377,CCOC(=O)N=C=S.N#CCc1c[nH]c2ccc(N)cc12>>CCOC(=O)NC(=S)Nc1ccc2[nH]cc(CC#N)c2c1,,CC#N,O,,,test
US20150329535A1,CN(CCCCC(=O)Nc1ccc(CO)cc1)C(=O)OC(C)(C)C>>CNCCCCC(=O)Nc1ccc(CO)cc1,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20150094436A1,CCCCC(CC)C[Si](Cl)(Cl)Cl.CCCCCCCC[Mg]Br>>CCCCCCCC[Si](Cl)(Cl)CC(CC)CCCC,,C1CCOC1,CCOCC,,,test
US20070287737A1,CC(=O)NNC(=O)c1ccncc1Nc1ccc(I)cc1F.N#CC(Cl)(Cl)Cl>>CNc1nnc(-c2ccncc2Nc2ccc(I)cc2F)o1,,CC(=O)N(C)C,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140179667A1,Cc1nnn(C)c1-c1cc2c(c(N)c1I)CCNC2=O.O=S(=O)(Cl)Cl>>Cc1nnn(C)c1-c1c(Cl)c2c(c(N)c1I)CCNC2=O,,CC(=O)O,,,,test
US20090137561A1,COC(=O)c1ccc(-c2cc(OC3CCCCO3)ccc2F)c(C(C)(C)C)c1>>CC(C)(C)c1cc(CO)ccc1-c1cc(OC2CCCCO2)ccc1F,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20100311966A1,O=C(N1CC[C@H](NCc2ccccc2)[C@H](OCC(F)F)C1)C(F)(F)F>>N[C@H]1CCN(C(=O)C(F)(F)F)C[C@H]1OCC(F)F,[Pd],CO,,,,test
US05854232,O=C(NC12CC3CC(CC(C3)C1)C2)C(CCO)(Cc1ccncc1)Cc1ccncc1>>O=C1N(C23CC4CC(CC(C4)C2)C3)CCC1(Cc1ccncc1)Cc1ccncc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100298339A1,CS(=O)(=O)OCCn1cc(-c2cccc3nc(Nc4ccc(OCCN5CCCC5)cc4)nn23)cn1.Nc1n[nH]c(S)n1>>Nc1nnc(SCCn2cc(-c3cccc4nc(Nc5ccc(OCCN6CCCC6)cc5)nn34)cn2)[nH]1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150141406A1,CCC(Br)CC.O=c1[nH]ccc2[nH]cc(Br)c12>>CCC(CC)n1cc(Br)c2c(=O)[nH]ccc21,,CN(C)C=O,,[H-].[Na+],,test
US06627651B1,CCCBr.O=Cc1cccc(O)c1>>CCCOc1ccccc1C=O,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20150158846A1,Cc1ccc(S(=O)(=O)OCCNC(=O)OC(C)(C)C)cc1.Cn1cc(Br)cc(Nc2cccc(O)n2)c1=O>>Cn1cc(Br)cc(Nc2cccc(OCCNC(=O)OC(C)(C)C)n2)c1=O,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100266504A1,CN(C)C=O.Cc1ccccc1.O=C(O)c1ccc(Cl)nc1Cl>>O=C(NCc1ccccc1)c1ccc(Cl)nc1Cl,,Cc1ccccc1,,O=C(Cl)C(=O)Cl,,test
US20140275160A1,CO.O=C(O)CCC/C=C\CC1C(O)CC(O)C1/C=C/C(O)COc1cccc(C(F)(F)F)c1>>COC(=O)CCC/C=C\C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1/C=C/[C@@H](O)COc1cccc(C(F)(F)F)c1,CC(=O)O,,,,,test
US04578381,CCOC=CC(=O)Nc1cccc(C(=O)OC)c1>>COC(=O)c1cccc2[nH]c(=O)ccc12,,O=S(=O)(O)O,,,,test
US20110136787A1,O=C1C=CC(c2ccccc2)CC1.[Li]c1ccccc1>>O=C1CC[C@@H](c2ccccc2)[C@H](c2ccccc2)C1,,CCOCC,,FB(F)F,,test
US20140142307A1,CCCCCCCCCCBr.ClCc1ccc2ccccc2n1.Clc1nc[nH]c1Cl>>CCCCCCCCCCN1CC(C)=Cc2ccccc21.Clc1[nH]c[nH+]c1Cl.[Br-],,CC#N,,Cl,[K+].[OH-],test
US20030232832A1,CC(=N)NO.CCC(c1nn2cccc2c(=O)n1CC(=O)OC)N(CCCNC(=O)OC(C)(C)C)C(=O)c1ccc(C)cc1>>CCC(c1nn2cccc2c(=O)n1Cc1nc(C)no1)N(CCCNC(=O)OC(C)(C)C)C(=O)c1ccc(C)cc1,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US05817652,CC(C)[Si](C(C)C)(C(C)C)n1cc(SC(=O)c2ccccc2)c(C(=O)c2ccccc2)c1.CCCCC1(CC)CN1>>CCCCC(N)(CC)CSc1c[nH]cc1C(=O)c1ccccc1,,CCOC(C)=O,CO,Cl,[Na+].[OH-],test
US20130150343A1,C[C@H]1CCCCN1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)CO[Si](c5ccccc5)(c5ccccc5)C(C)(C)C)nn4-c4cccc(OCCOC5CCCCO5)c4)c4ccccc43)cn12>>C[C@H]1CCCCN1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(C(C)(C)CO[Si](c5ccccc5)(c5ccccc5)C(C)(C)C)nn4-c4cccc(OCCO)c4)c4ccccc43)cn12,,CO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20140309207A1,CN(C)Cc1csc(N)n1.COC(=O)N1CCC2(CNc3ccc(Cl)cc32)C1.O=C(n1ccnc1)n1ccnc1>>COC(=O)N1CCC2(C1)CN(C(=O)Nc1nc(CN(C)C)cs1)c1ccc(Cl)cc12,,C1CCOC1,,CN(C)c1ccccn1,,test
US05120759,Cc1ccc(S(=O)(=O)OCC[C@]2(O)CCc3cc(F)ccc3[C@H]2C(C)C)cc1>>Oc1ccc2ccccc2c1,,CS(C)=O,,CCN(C(C)C)C(C)C,,test
US20100331306A1,CCOCC.Fc1ccc2ncc(-c3ccccn3)cc2c1.N#Cc1n[nH]c2ncnc(N)c12>>C[C@@H](c1nc2ccc(F)cc2cc1-c1ccccn1)n1nc(C#N)c2c(N)ncnc21,,CN(C)C=O,,[H-].[Na+],O=C([O-])[O-].[K+].[K+],test
US20070213331A1,COC(=O)[C@H]1C[C@@H](F)CN1C(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1C[C@H](F)C[C@@H]1CO,,C1CCOC1,,[BH4-].[Li+],,test
US06689806B1,CC(C)N=C=O.O=C1Cc2c(CCO)cccc2N1>>CC(C)NC(=O)OCCc1cccc2c1CC(=O)N2,,C1CCOC1,CN(C)C=O,O,,test
US05922742,O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F.Oc1ccccn1>>O=S(=O)(Oc1ccccn1)C(F)(F)F,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040121994A1,CCOP(=O)(CC(=O)O)OCC.NC1CCC(O)CC1>>CCOP(=O)(CC(=O)NC1CCC(O)CC1)OCC,,CC(=O)N(C)C,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US06069157,N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1-c1cccs1.O=C1CCC(=O)N1Br>>N#Cc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1-c1ccc(Br)s1,,CC#N,,CCOCC,O,test
US20020156087A1,C1COCCN1.CC(C)(C)OC(=O)NCCNc1nc(OS(=O)(=O)C(F)(F)F)cc(-c2ccc(C#N)cc2)n1>>CC(C)(C)OC(=O)NCCNc1nc(-c2ccc(C#N)cc2)cc(N2CCOCC2)n1,,CC#N,,O,,test
US20050113440A1,COC(=O)COc1ccc(SCc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)cc1C>>Cc1cc(SCc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)ccc1OCC(=O)O,,O,,,,test
US20100055576A1,CC(C)(C)c1cccc(O)c1.CCS(=O)(=O)Cl>>CCS(=O)(=O)Oc1cccc(C(C)(C)C)c1,,Cc1ccccc1,O,CCN(CC)CC,,test
US06576656B1,CCN(CC)CCN1C(=O)C(=O)c2c1cc(I)cc2C(F)(F)F.Fc1ccc(Br)c(F)c1>>CCN(CC)CCN1C(=O)C(O)(c2ccc(F)cc2F)c2c1cc(I)cc2C(F)(F)F,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20160009726A1,COC(=O)c1ccc2oc([Si](C)(C)C)cc2n1>>COC(=O)c1ccc2occc2n1,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20150141400A1,CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(CN3C[C@@H](CCN(Cc4ccc(OC)cc4OC)S(C)(=O)=O)N(C(=O)OC(C)(C)C)C3=O)c(OC(F)(F)F)cc2c1=O>>CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(CN3C[C@@H](CCNS(C)(=O)=O)NC3=O)c(OC(F)(F)F)cc2c1=O,,O=C(O)C(F)(F)F,,,,test
US20110301145A1,CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3cc(Cl)n[nH]c3=O)nc2)C(=O)C1.CC1(C)OB(c2ccc(F)c(NC(=O)c3cc4c(s3)CCCC4)c2)OC1(C)C>>CC(C)(C)OC(=O)N1CCN(c2ccc(Nc3cc(-c4ccc(F)c(NC(=O)c5cc6c(s5)CCCC6)c4)n[nH]c3=O)nc2)C(=O)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20160159815A1,CC(C)(O)CCl.COC(=O)c1ccc(O)c(Cl)c1>>COC(=O)c1ccc(OCC(C)(C)O)c(Cl)c1,,CCOC(C)=O,CO,O,O=C([O-])[O-].[K+].[K+],test
US20160264562A1,CCOC(=O)[C@@H](C)OC(=O)C1=C(CN2CCOCC2)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl.CO>>COC(=O)C1=C(CN2CCOCC2)NC(c2nccs2)=N[C@H]1c1ccc(F)cc1Cl,,CO,,[Li],,test
US20060276464A1,CN(CCNS(=O)(=O)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F)C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1>>CN(CCNS(=O)(=O)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F)C(=O)NC1CCNCC1,,ClCCl,,CCOC(C)=O,Cl,test
US20140371201A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Fc1cc(Br)cc(OC(F)F)c1>>CC1(C)OB(c2cc(F)cc(OC(F)F)c2)OC1(C)C,,CCOC(C)=O,,CC(=O)[O-].[K+],,test
US20140045872A1,CCOC(=O)NCCc1ccc(Br)cc1>>O=C1NCCc2ccc(Br)cc21,,O=P(Cl)(Cl)Cl,,O=P12OP3(=O)OP(=O)(O1)OP(=O)(O2)O3,,test
US04042373,O=P(Cl)(Cl)Cl.Oc1c2c(nn1-c1ccc(Cl)cc1F)CCSC2>>Fc1cc(Cl)ccc1-n1nc2c(c1Cl)CSCC2,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20100056530A1,O=C(NC(=S)Nc1ncccc1OCc1ccccc1)c1ccccc1>>NC(=S)Nc1ncccc1OCc1ccccc1,,O,,CCO,O=C([O-])[O-].[K+].[K+],test
US20050209226A1,C1CC(OCC2CC2)CCN1.O=C1COc2ccccc2N1CCCCl>>O=C1COc2ccccc2N1CCCN1CCC(OCC2CC2)CC1,,CC#N,,[I-].[K+],O=C([O-])O.[Na+],test
US20080207645A1,CCC1(C)Cc2c(c(N3CCOCC3)nc3sc4c(Cl)ncnc4c23)CO1.NCc1cccnc1>>CCC1(C)Cc2c(c(N3CCOCC3)nc3sc4c(NCc5cccnc5)ncnc4c23)CO1,,CCO,,,,test
US20050107360A1,Clc1cccc(CBr)c1.O=C1Cc2ccc(O)cc2CCN1>>O=C1Cc2ccc(OCc3cccc(Cl)c3)cc2CCN1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040176593A1,Cc1cc(Cl)c(NC(=O)CBr)c(Cl)n1.OCCN1CCNCC1>>Cc1cc(Cl)c(NC(=O)CN2CCN(CCO)CC2)c(Cl)n1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US05102891,CCCCN=C=O.Cc1cn(NCCCc2ccncc2F)c2ccc(O)cc12>>CCCCNC(=O)Oc1ccc2c(c1)c(C)cn2NCCCc1ccncc1F,,C1CCOC1,,O=C([O-])[O-].[K+].[K+],,test
US20140121206A1,CC(C)(O)c1cnc(N2C[C@@]3(CCC[C@](C)(Cn4cnc5ccc(C#N)cc54)C3)OC2=O)cn1.OCCO>>CC(C)(OCCO)c1cnc(N2C[C@@]3(CCC[C@](C)(Cn4cnc5ccc(C#N)cc54)C3)OC2=O)cn1,,O,,O=S(=O)(O)O,,test
US20080249138A1,NS(=O)(=O)c1ccccc1.O=C(O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1>>O=C(NS(=O)(=O)c1ccccc1)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1,,C1CCOC1,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US20130281452A1,C=C(C)c1cc(N2CCOCC2)cc(F)c1C(=O)NCc1ccc(Cl)cc1>>CC(C)c1cc(N2CCOCC2)cc(F)c1C(=O)NCc1ccc(Cl)cc1,,CO,,,,test
US20040038959A1,COC(=O)c1cccc(CBr)c1.Oc1cc2ccc(Br)nc2cn1>>COC(=O)c1cccc(Cn2cc3nc(Br)ccc3cc2=O)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04956465,CCOC(=O)CC#N.CCOC(=O)c1cn(C2CC2)c2c(C#N)c(Cl)c(F)cc2c1=O>>CCOC(=O)c1cn(C2CC2)c2c(C#N)c(C(C#N)C(=O)OCC)c(F)cc2c1=O,,C1COCCO1,,Cl,CC(C)(C)[O-].[K+],test
US20100056524A1,CNCCN(C)C.O=[N+]([O-])c1ccc(Cl)nc1>>CN(C)CCN(C)c1ccc([N+](=O)[O-])cn1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20070072893A1,CC(C)(C)[Si](C)(C)OCCCCNc1c(N)cnc2ccccc12.CCCCC(OC)(OC)OC>>CCCCc1nc2cnc3ccccc3c2n1CCCCO[Si](C)(C)C(C)(C)C,,Cc1ccccc1,,,,test
US08859615B2,C#CC[C@@H]1OC(C)(C)O[C@H]1CCCCCCC.CCC=O>>CC#CC(O)CC[C@@H]1OC(C)(C)O[C@H]1CCCCCCC,,C1CCOC1,,[Li]CCCC,,test
US04490527,CN(C)Cc1ccc(CSCCN)o1.CSC1=NS(=O)(=O)c2cscc21>>CN(C)Cc1ccc(CSCCNC2=NS(=O)(=O)c3cscc32)o1,,CCO,,,,test
US20130225554A1,CONC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1>>CONC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2O,[Pd],CO,,,,test
US20110152273A1,CCN(CC)CC.COC(=O)c1c(C#N)cc(Cl)nc1Cl.Cc1cc(N)ccc1F>>CCc1cc(Nc2nc(Cl)cc(C#N)c2C(=O)OC)ccc1F,,CC#N,CCOC(C)=O,O,,test
US04743685,NN1CCNC1=O.O=C(O)C=Cc1cc(=O)c(OCc2ccccc2)c[nH]1>>O=C(C=Cc1cc(=O)c(OCc2ccccc2)c[nH]1)NN1CCNC1=O,,CN(C)C=O,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20160022642A1,CS(=O)(=O)OCCOCCOCCN=[N+]=[N-].Cc1cc(C)cc(O)c1>>Cc1cc(C)cc(OCCOCCOCCN=[N+]=[N-])c1,,O,,CN(C)C=O,O=C([O-])[O-].[Na+].[Na+],test
US20100234395A1,CNO.COc1ccc(-n2nc(C3CCNCC3)cc2-c2ccc(OC)c(F)c2)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CNC(=O)N1CCC(c2cc(-c3ccc(OC)c(F)c3)n(-c3ccc(OC)cc3)n2)CC1,,C1CCOC1,,CCN(CC)CC,Cl,test
US20100190777A1,CCCS(=O)(=O)Nc1ccc(Cl)c(C(=O)Cl)c1F.Nc1cccnc1>>CCCS(=O)(=O)Nc1ccc(Cl)c(C(=O)Nc2cccnc2)c1F,CN(C)c1ccncc1,ClCCl,,O,,test
US05952362,CC(=O)Nc1cc([N+](=O)[O-])c(C)cc1C>>Cc1cc(C)c([N+](=O)[O-])cc1N,,CCO,,O,O=S(=O)(O)O,test
US20130150341A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1CNCCC(O)C1>>CC1CC(O)CCN(C(=O)OC(C)(C)C)C1,CN(C)c1ccncc1,CC#N,,,,test
US20040082607A1,CCCCOc1c(CNC(=O)OC(C)(C)C)n(CC(C)C)c(=O)c2ccc(/C=C/c3cscn3)cc12.Cl>>CCCCOc1c(CN)n(CC(C)C)c(=O)c2ccc(/C=C/c3cscn3)cc12.Cl,,CCOC(C)=O,,,,test
US04076756,C1CCCCC1.CC(C)OB([O-])[O-].Clc1ccccc1.c1ccccc1>>c1ccc(B(c2ccccc2)c2ccccc2)cc1,,O,,[Na],,test
US20140315888A1,CC(C)(C)OC(=O)N1CCN(c2nc3ncc(Br)cc3n3cnnc23)CC1>>Brc1cnc2nc(N3CCNCC3)c3nncn3c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06342504B1,Fc1ccccc1CCl.NC(N)=S>>Cl.NC(S)=[NH+]Cc1ccccc1F,,CCOCC,,CO,,test
US20030134853A1,CCOC(=N)c1ccc(O)cc1.N#Cc1ccc(NC2CCCCC2)c(N)c1>>N#Cc1ccc2c(c1)nc(-c1ccc(O)cc1)n2C1CCCCC1,,CO,,Cl,,test
US20150361060A1,CCOC(=O)C=NO.NCCN1CCCC(F)(F)CC1>>O=C(C=NO)NCCN1CCCC(F)(F)CC1,,CCO,,,,test
US20060025433A1,CNC1CCC(n2ccnc2)CC1.N#CSc1nc(NCc2ccccc2OC(F)(F)F)ncc1[N+](=O)[O-]>>O=[N+]([O-])c1cnc(NCc2ccccc2OC(F)(F)F)nc1NC[C@@H]1CC[C@@H](n2ccnc2)CC1,,CCO,,CCN(CC)CC,,test
US20110082300A1,CC1=CC(C)N2C1=C(c1ccc(-c3cn(CCCCCc4ccc(CCC5(NC(=O)OC(C)(C)C)COC(C)(C)OC5)cc4)nn3)cc1)c1c(C)cc(C)n1C2(F)F>>CC1=CC(C)N2C1=C(c1ccc(-c3cn(CCCCCc4ccc(CCC(N)(CO)CO)cc4)nn3)cc1)c1c(C)cc(C)n1C2(F)F,,ClCCl,,CCOCC,FB(F)F,test
US20160039780A1,CO.O=C(O)CCC12CCC(O)(CC1)CC2>>COC(=O)CCC12CCC(O)(CC1)CC2,,CO,,C[Si](C)(C)C=[N+]=[N-],,test
US20140206681A1,NCc1nccnc1Cl.O=C(O)[C@@H]1CC[C@@H]2CCCC(=O)N2C1>>O=C(NCc1nccnc1Cl)[C@@H]1CC[C@@H]2CCCC(=O)N2C1,,ClCCl,,Cl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070203156A1,CC(C)(C)[Si](C)(C)OC(CCCCCCc1ccccc1)c1ncc(-c2cccc(O)c2)o1>>O=C(CCCCCCc1ccccc1)c1ncc(-c2cccc(O)c2)o1,,CCOC(C)=O,,,,test
US20120245161A1,OCCCl.Oc1cccc2cc[nH]c12>>ClCCOc1cccc2cc[nH]c12,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05081131,CSC1=Nc2cccc3cccc1c23.NCCCc1nnc(-c2ccccc2-c2ccccc2)s1>>c1ccc(-c2ccccc2-c2nnc(CCCNC3=Nc4cccc5cccc3c45)s2)cc1,,CCO,,I,,test
US20080249130A1,COC(=O)c1nc2ccc(N)cc2s1.Cc1csc(N)n1.Cc1csc2nc(-c3ccccc3C(=O)O)cn12.O=C(O)c1ccccc1-c1cn2ccsc2n1>>COC(=O)c1nc2ccc(NC(=O)c3ccccc3-c3cn4c(C)csc4n3)cc2s1.Cc1csc2nc(-c3ccccc3C(=O)O)cn12,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080027092A1,CCOC(=O)CBr.Fc1ccc2nccc(-c3n[nH]c4cccc(C(F)(F)F)c34)c2c1>>CCOC(=O)Cn1nc(-c2ccnc3ccc(F)cc23)c2c(C(F)(F)F)cccc21,,C1CCOC1,,[H-].[Na+],,test
US20040024010A1,CCOC(=O)CCc1c(C=C2C(=O)Nc3ccc(Cl)cc32)[nH]c(C(=O)OCC)c1C>>Cc1c(C(=O)O)[nH]c(C=C2C(=O)Nc3ccc(Cl)cc32)c1CCC(=O)O,,CCO,O,Cl,[K+].[OH-],test
US20060247292A1,CC(C)(Cc1cccc(Cl)c1)CC(O)(C=Nc1cccc2[nH]ncc12)C(F)(F)F>>CC1(C)Cc2cc(Cl)ccc2C(Nc2cccc3[nH]ncc23)C(O)(C(F)(F)F)C1,,CCOC(C)=O,,BrB(Br)Br,O=C([O-])O.[Na+],test
US04727081,CN=C=S.NNC(=O)NCCCOc1cccc(CN2CCCCC2)c1>>CNC(=S)NNC(=O)NCCCOc1cccc(CN2CCCCC2)c1,,C1CCOC1,,,,test
US20120010190A1,COc1ccc(C(=O)/C=C/c2cc(Cl)cc(Cl)c2)cn1>>O=C(/C=C/c1cc(Cl)cc(Cl)c1)c1ccc(=O)[nH]c1,,C1COCCO1,,Cl,,test
US20070037817A1,C[Sn](C)(C)N=[N+]=[N-].N#Cc1cccnc1N1CCN2[C@@H](C#Cc3cccc(Cl)c3)CC[C@H]2C1>>Clc1cccc(C#C[C@H]2CC[C@H]3CN(c4ncccc4-c4nn[nH]n4)CCN23)c1,,O,,CN(C)C=O,,test
US20080188484A1,CC(C)N1CCC(Oc2cc3cc(C(=O)N4CCN(S(=O)(=O)N5CCCCC5)CC4)[nH]c3cc2Br)CC1.CC(C)OS(C)(=O)=O>>CC(C)N1CCC(Oc2cc3cc(C(=O)N4CCN(S(=O)(=O)N5CCCCC5)CC4)n(C(C)C)c3cc2Br)CC1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],O=C([O-])O.[Na+],test
US05939460,COc1cc(C=O)cc(OC)c1O.Nc1ccccc1>>COc1cc(C=Nc2ccccc2)cc(OC)c1O,,CO,,,,test
US20140113882A1,CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)[C@@H](C(=O)O)C1.CNOC>>CON(C)C(=O)[C@H]1CN(C(=O)OC(C)(C)C)CCN1C(=O)OC(C)(C)C,,CC(=O)N(C)C,,Cl,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100222366A1,O=C(N[C@@H]1CCC2(C[C@@H]1C(=O)O)OCCO2)c1ccccc1>>O=C1CC[C@@H](NC(=O)c2ccccc2)[C@@H](C(=O)O)C1,,CC#N,,Cl,,test
US20040147519A1,CC(C)(C)OC(=O)NCCc1ccc(-c2ccccn2)cc1>>NCCc1ccc(-c2ccccn2)cc1,,O=C(O)C(F)(F)F,,ClCCl,,test
US20070004725A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O.O=Cc1ccccc1F>>CC(C)(C)OC(=O)NC(Cc1ccc(Oc2ccccc2C=O)cc1)C(=O)O,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20060063779A1,C=O.O=C(Nc1ccc(Cl)c(-c2ccccn2)c1)c1ccc(CN2CCNCC2=O)cc1>>CN1CCN(Cc2ccc(C(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)cc2)C(=O)C1,,CC(=O)O,CN(C)C=O,Cl,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20160272628A1,CNS(=O)(=O)CCN1C(C)c2cc(-c3cn(C(=O)OC(C)(C)C)c4cc(F)ccc34)ccc2S1(=O)=O>>CNS(=O)(=O)CCN1C(C)c2cc(-c3c[nH]c4cc(F)ccc34)ccc2S1(=O)=O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20030092677A1,CC(=O)OC(C)=O.N#Cc1cccc(C2=Nc3ccc(C#CC4=CCNCC4)cc3NC(=O)C2)c1>>CC(=O)N1CC=C(C#Cc2ccc3c(c2)NC(=O)CC(c2cccc(C#N)c2)=N3)CC1,,C1CCOC1,,,,test
US04963530,CC(C)CC[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)N1CCOCC1.Cl>>CC(C)CC[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)N1CCOCC1.Cl,,C1COCCO1,CCO,,,test
US20100137250A1,COC(=O)Cc1cc(C(OC)c2ccc(S(C)(=O)=O)cc2)c2cc(F)ccc2c1>>COC(c1ccc(S(C)(=O)=O)cc1)c1cc(CC(=O)O)cc2ccc(F)cc12,,CC(=O)O,,,,test
US20150152127A1,CNC1=N[C@H]2[C@H](O[C@H]([C@@H](Oc3ccc([N+](=O)[O-])cc3)C(F)(F)F)[C@@H](O)[C@@H]2O)S1>>CNC1=N[C@H]2[C@H](O[C@H]([C@@H](Oc3ccc(N)cc3)C(F)(F)F)[C@@H](O)[C@@H]2O)S1,[Pd],CO,,,,test
US20100331326A1,Cc1ccncc1N1CCN(c2csc3ccnc(Cl)c23)C1=O>>Cc1ccncc1N1CCN(c2csc3ccncc23)C1=O,[Zn],CC(=O)O,ClCCl,CO,,test
US06350907B1,C[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCc1ccc(Oc2ccccc2)c(F)c1)CC(=O)OC(C)(C)C)C(C)(C)C)c1ccccc1>>C[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCc1ccc(Oc2ccccc2)c(F)c1)CC(=O)O)C(C)(C)C)c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050171108A1,CCCc1ccc2nc(C(F)(F)F)c(S(=O)(=O)N=CN(C)C)n2n1>>CCCc1ccc2nc(C(F)(F)F)c(S(N)(=O)=O)n2n1,,C1COCCO1,,Cl,,test
US20090076078A1,CC1(N2CCC(N3C(=O)N[C@@H]4CCCC[C@H]43)CC2)CCNCC1.O=C(O)C1CC1>>CC1(N2CCC(N3C(=O)N[C@@H]4CCCC[C@H]43)CC2)CCN(C(=O)C2CC2)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04936906,CCCC(=O)OC1=CC(=O)CC(CCCCC(=O)OC)C1C(=O)OC>>CCCC(=O)C1=C(O)C(C(=O)OC)C(CCCCC(=O)OC)CC1=O,CN(C)c1ccncc1,ClCCl,,,,test
US20050038056A1,COc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(C[C@H](NC(=O)OC(C)(C)C)C3CCCCC3)c2=O)c1F>>COc1cccc(C2=C(C)N(Cc3c(F)cccc3F)CN(C[C@H](N)C3CCCCC3)C2)c1F,,ClCCl,,O=C(O)C(F)(F)F,,test
US04112095,Fc1cccc(-c2ccc(Cl)nn2)c1.NNC=O>>Fc1cccc(-c2ccc3nncn3n2)c1,,CCCCO,,,,test
US05580872,CC(C)(C)OCl.Cc1cc(Cl)c(F)cn1>>Cc1ncc(F)c(Cl)c1Cl,,ClC(Cl)Cl,,O,,test
US20120295884A1,CC(C)(C)[SiH2]OC(C)(C)[C@H]1CC[C@@H](C(=O)Nc2cccc(OC(F)(F)F)c2)N1Cc1ccccc1>>CC(C)(C)[SiH2]OC(C)(C)[C@H]1CC[C@@H](C(=O)Nc2cccc(OC(F)(F)F)c2)N1,[Pd],C1CCOC1,,,,test
US20100331306A1,CC(=O)c1nc2ccc(F)cc2cc1-c1cncc(F)c1>>CC(O)c1nc2ccc(F)cc2cc1-c1cncc(F)c1,,C1CCOC1,,[BH4-].[Na+],,test
US20040157836A1,CCBr.N#CCC(=O)N1CCCCC1.[Li]CCCC>>CCC(C#N)(CC)C(=O)N1CCCCC1,,C1CCOC1,,CCCCCC,,test
US20100160286A1,Cn1ccc(NC(=O)c2cc(O)cc(OC(CF)CF)c2)n1.O=C(c1ccc(F)c(Cl)c1)N1CCC1>>Cn1ccc(NC(=O)c2cc(Oc3ccc(C(=O)N4CCC4)cc3Cl)cc(OC(CF)CF)c2)n1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130317065A1,COc1ccc2c(Cc3cccc(C(=O)O)n3)c(-c3ccsc3)[nH]c2c1.CS(N)(=O)=O>>COc1ccc2c(Cc3cccc(C(=O)NS(C)(=O)=O)n3)c(-c3ccsc3)[nH]c2c1,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20140371278A1,C=CCC1(S(=O)(=O)Nc2cc3ocnc3c(F)c2Nc2ccc(Br)cc2Cl)CC1.C[N+]1([O-])CCOCC1.O=[Os](=O)(=O)=O>>O=S(=O)(Nc1cc2ocnc2c(F)c1Nc1ccc(Br)cc1Cl)C1(CC(O)CO)CC1,O=[Os](=O)(=O)=O,C1CCOC1,,O,,test
US20090088457A1,CC(C)(C)[Si](C)(C)Cl.O[C@H]1CCN(c2nccs2)C1>>CC(C)(C)[Si](C)(C)O[C@H]1CCN(c2nccs2)C1,,CN(C)C=O,,O,c1c[nH]cn1,test
US05300503,CC1(C)N=C(N)N=C(N)N1OCc1cc(Cl)c(Cl)cc1Cl>>CC1(C)N=C(N)N=C(N)N1OCc1cc(Cl)c(Cl)cc1Cl,,O,,Br,CCN(CC)CC,test
US06335324B1,C1CCNCC1.O=C(Cl)Cl>>O=C(Cl)N1CCCCC1,,ClCCl,,,,test
US20100239527A1,COC(=O)c1[nH]c2cnc(OC)cc2c1-c1cccnc1OC.Fc1ccccc1CCl>>COC(=O)c1c(-c2cccnc2OC)c2cc(OC)ncc2n1Cc1ccccc1F,,CN(C)C=O,O,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100130471A1,COC(=O)NCCO.O=S(Cl)Cl>>COC(=O)N1CCOS1=O,,ClCCl,,CCN(CC)CC,CO,test
US04382090,CN(C)CCCC#N.S>>CN(C)CCCC(N)=S,,CCN(CC)CC,,c1ccncc1,,test
US20020090728A1,CC(C)(C)OC(=O)NCC(=O)O.Fc1nc(F)nc(F)n1>>CC(C)(C)OC(=O)NCC(=O)F,,ClCCl,,c1ccncc1,,test
US20100240712A1,Cc1cc(C(O)(c2ccc(F)cc2)C(F)(F)F)cc(C)c1NC(=O)c1cccc(N)c1.O=C(Cl)c1ccccc1>>Cc1cc(C(O)(c2ccc(F)cc2)C(F)(F)F)cc(C)c1NC(=O)c1cccc(NC(=O)c2ccccc2)c1,,ClCCl,,c1ccncc1,,test
US04525309,ClC(Cl)Cl.OO.[O-]B([O-])C(CCCC1COCCO1)OCc1ccccc1>>CC[C@@H](O)[C@@H](CCCC(C)=O)OCc1ccccc1,,ClC(Cl)Cl,,O=S(=O)(O)O,,test
US20020004504A1,O=C(CCCBr)c1ccc2[nH]c(=O)oc2c1.O=C(O)C(F)(F)F>>O=C(OCCCCc1ccc2[nH]c(=O)oc2c1)C(F)(F)F,,O,,CC[SiH](CC)CC,,test
US20150105404A1,CNOC.Cn1cncc1C(O)(c1ccc(C(F)(F)F)nc1)c1ccc2nc(Cl)c(-c3ccccc3)c(Cl)c2c1>>CON(C)c1nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1-c1ccccc1,,CN(C)C=O,,Cl,,test
US20070244095A1,Cc1cc2c(cc1C(F)(F)F)NCCC[C@@H]2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1.O=C(Cl)Cl>>Cc1cc2c(cc1C(F)(F)F)N(C(=O)Cl)CCC[C@@H]2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,CCOC(C)=O,test
US20150218102A1,C1CC(N2CCNCC2)C1.O=C(O)c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1>>O=C(c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1)N1CCN(C2CCC2)CC1,,CO,CS(C)=O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20090076313A1,CCC=C(C)C(O)CCCCC.ICI>>CCCCCC(O)C1(C)CC1CC,,COC(C)(C)C,,,,test
US20130331378A1,COC(=O)c1cccc(C(O)c2c(-c3ccccc3)nn3c([Si](C)(C)C)c(Cl)ccc23)n1>>COC(=O)c1cccc(C(O)c2c(-c3ccccc3)nn3cc(Cl)ccc23)n1,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20150045349A1,CCC(C)n1cc(-c2ccn(C)n2)c(OC)c(C#N)c1=O.NN>>CCC(C)n1cc(-c2ccn(C)n2)c2[nH]nc(N)c2c1=O,,CCO,,O,,test
US08877747B2,CC(=O)OC(C)=O.O=C1C(c2cccnc2)=C(c2cc(F)cc(F)c2)c2ccc(OCCCN3CCNCC3)cc21>>CC(=O)N1CCN(CCCOc2ccc3c(c2)C(=O)C(c2cccnc2)=C3c2cc(F)cc(F)c2)CC1,,ClCCl,,c1ccncc1,,test
US20100260682A1,CC(C)(C)OC(=O)NCCCCCC(=O)OCC(COP(=O)(OCCNC(=O)CCOCCOCCOCCOCCNC(=O)OCc1ccccc1)OCc1ccccc1)OC(C)(C)C>>CC(C)(C)OC(=O)NCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)CCOCCOCCOCCOCCN)OC(C)(C)C,[Pd],CC(C)(C)O,,,,test
US20140288123A1,Cc1cc(C(F)(F)F)nc(O)c1C#N>>Cc1cc(C(F)(F)F)nc(O)c1CN,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20160016935A1,C[C@@H]1CC[C@@H](Oc2cc(O)ccn2)CN1C(=O)OC(C)(C)C.O=C([O-])C(F)(F)Cl>>C[C@@H]1CC[C@@H](Oc2cc(OC(F)F)ccn2)CN1C(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090156600A1,CCOC(=O)CC(=O)CC.CS(=O)(=O)c1ccc(CBr)cc1>>CCOC(=O)C(Cc1ccc(S(C)(=O)=O)cc1)C(=O)CC,,C1CCOC1,O,CC(C)(C)O,CC(C)(C)[O-].[K+],test
US20060173043A1,C=C(CC(=O)OC)C(=O)[O-].C=CCNCc1ccccc1>>C=CCN(Cc1ccccc1)C(=O)C(=C)CC(=O)OC,CN(C)c1ccncc1,ClCCl,,CCN=C=NCCCN(C)C,,test
US05866583,c1ccc(C2=NCCc3ccccc32)nc1>>c1ccc(C2NCCc3ccccc32)nc1,O=[Pt]=O,CCO,,[H][H],,test
US20130324516A1,CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncnc2ccc(Cl)nc12.Cc1cccc(CN)c1>>Cc1ccccc1CNc1ccc2ncnc(N)c2n1,,CC(=O)N(C)C,,CCN(C(C)C)C(C)C,,test
US20150232481A1,Brc1ccccc1CC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(C=O)nn23)CC1>>C=CCOC1(C)CCN(c2c([C@H](OC(C)(C)C)C(=O)OCC)c(C)nc3cc(C=CCc4ccccc4Br)nn23)CC1,,C1CCOC1,,[H-].[Na+],,test
US20140274960A1,II.Nc1ccc(Cl)c(F)c1>>Nc1cc(F)c(Cl)cc1I,,O,,O=C([O-])O.[Na+],,test
US05872137,OCCCCc1ccccc1.Oc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl>>ClC(Cl)=CCOc1cc(Cl)c(OCCCCc2ccccc2)c(Cl)c1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060025597A1,Nc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O.O=Cc1ccco1>>O=C1CCC(N2Cc3c(NCc4ccco4)cccc3C2=O)C(=O)N1,,CO,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130079335A1,CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(OS(=O)(=O)C(F)(F)F)ccc2-n2c(C)nnc21.OB(O)c1ccn[nH]1>>CCNC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(-c3ccn[nH]3)ccc2-n2c(C)nnc21,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],test
US05171744,CI.O=C(O)C(O)c1ccsc1>>COC(=O)C(O)c1ccsc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120238587A1,CC1(C)OB(c2cnc(Cl)c(NS(=O)(=O)c3ccc(F)cc3F)c2)OC1(C)C.Clc1ccc2ncnc(NC3CCOCC3)c2n1>>O=S(=O)(Nc1cc(-c2ccc3ncnc(NC4CCOCC4)c3n2)cnc1Cl)c1ccc(F)cc1F,,C1COCCO1,,O=C([O-])O.[Na+],,test
US20130338066A1,CC1(C)OC(N[C@@H](CCO[Si](C)(C)C(C)(C)C)c2ccccc2F)=NS(=O)(=O)C1(C)c1cccc(Br)c1>>CC1(C)OC(N[C@@H](CCO)c2ccccc2F)=NS(=O)(=O)C1(C)c1cccc(Br)c1,,CO,,Cl,,test
US20130079333A1,O=C(CBr)Nc1ccc(Cl)cc1CO>>O=C1COCc2cc(Cl)ccc2N1,,CC(C)O,,CC(C)(C)[O-].[K+],,test
US04045499,C=C(C)C.CC(C)(c1ccc(O)c(Cl)c1)c1ccc(O)c(Cl)c1>>CC1(C)CC(C)(C)c2cc(Cl)c(O)cc21,,Cc1ccccc1,,,,test
US20090209607A1,Cn1ncc(Cl)c1-c1cc(C(=O)N[C@H](CNC(=O)OC(C)(C)C)Cc2ccccc2C(F)(F)F)sc1Cl>>Cn1ncc(Cl)c1-c1cc(C(=O)N[C@H](CN)Cc2ccccc2C(F)(F)F)sc1Cl,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100249119A1,CC(=O)OCC(=O)Cl.Cc1ccc(Oc2ccc3nc(N)sc3n2)cc1NC(=O)c1cccc(C2(C#N)CC2)c1>>Cc1ccc(Oc2ccc3nc(NC(=O)CO)sc3n2)cc1NC(=O)c1cccc(C2(C#N)CC2)c1,,c1ccncc1,,,,test
US04120863,CC(=O)Oc1ccc(C(F)(F)C(F)(F)C(F)(F)F)cc1>>Oc1ccc(C(F)(F)C(F)(F)C(F)(F)F)cc1,,CO,,Cl,,test
US20040127574A1,CC(C)(C)OC(=O)N1C(=O)OC(c2cccc(Cl)n2)C1Cc1ccc(C(F)(F)F)cc1>>CC(C)(C)OC(=O)NC(Cc1ccc(C(F)(F)F)cc1)C(O)c1cccc(Cl)n1,,CO,,O,[Na+].[OH-],test
US06713515B2,CCOC(=O)c1ccc(C(=C[Si](C)(C)C)c2cc3c(cc2C)C(C)(C)CCC3=O)cc1>>C=C(c1ccc(C(=O)OCC)cc1)c1cc2c(cc1C)C(C)(C)CCC2=O,,Cc1ccccc1,ClCCl,O=C(O)C(F)(F)F,,test
US05700445,O=C1Cc2cc([N+](=O)[O-])ccc2Sc2ccccc21>>Nc1ccc2c(c1)CC(=O)c1ccccc1S2,[Zn],CCO,O,[Ca+2].[Cl-].[Cl-],,test
US20080255152A1,CC(C)(C)OC(=O)NCCc1cc(F)c(O)c(F)c1.N#Cc1ccc(Cl)nc1>>CC(C)(C)OC(=O)NCCc1cc(F)c(Oc2ccc(C#N)cn2)c(F)c1,,CS(C)=O,,O,[H-].[Na+],test
US06306887B1,CC(C)CC(NC(=O)OCc1ccccc1)c1cc(C=O)on1.CCOC(=O)CC(=O)O>>CCOC(=O)C=Cc1cc(C(CC(C)C)NC(=O)OCc2ccccc2)no1,,O,,c1ccncc1,,test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(-c2ccccc2)nc1-c1ccc2c(c1)NC(=O)C2>>CCCC(C(=O)O)c1c(C)nc(-c2ccccc2)nc1-c1ccc2c(c1)NC(=O)C2,,CO,,[Na+].[OH-],,test
US06350749B1,CC(=O)CCl.O=C1C=C(S)CC(c2ccccc2Cl)C1>>CC(=O)CSC1=CC(=O)CC(c2ccccc2Cl)C1,,CCO,,C,C[O-].[Na+],test
US20100093748A1,Cc1ccc2[nH]c(C3(CN)CCNCC3)nc2c1.Clc1ncnc2[nH]ccc12>>Cc1ccc2[nH]c(C3(CN)CCN(c4ncnc5[nH]ccc45)CC3)nc2c1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20040242882A1,NC(N)=Nc1cccc2[nH]c3c(c12)C[C@@]1(O)C2Cc4ccc(O)c5c4[C@@]1(CCN2CC1CC1)[C@H]3O5>>NC(N)=Nc1ccc2c3c([nH]c2c1)[C@@H]1Oc2c(O)ccc4c2[C@@]12CCN(CC1CC1)C(C4)[C@]2(O)C3,,ClCCl,O=C(O)C(F)(F)F,,,test
US20050113356A1,COC(=O)CCC(C)(C)C>>CC(C)(C)CCC(=O)O,,ClCCl,O,[Na+].[OH-],,test
US20150087585A1,Nc1nc(N2CCC[C@@H](C(=O)N3CCCC3)C2)ncc1[N+](=O)[O-]>>Nc1cnc(N2CCC[C@@H](C(=O)N3CCCC3)C2)nc1N,[Pd],CCO,,[H][H],,test
US05108990,C=C(CC(NC=O)C(=O)OCC)CC(NC(=O)OC(C)(C)C)C(=O)OCC>>C=C(CC(N)C(=O)OCC)CC(NC=O)C(=O)OCC,,CCOCC,ClCCl,Cl,,test
US20080311075A1,C[C@H](O)c1ccccc1.O=C(O)C(Br)c1ccccc1>>C[C@H](OC(=O)C(Br)c1ccccc1)c1ccccc1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN=C=NCCCN(C)C,,test
US20080008682A1,COCCOC1=NC(N)(N)C2=NC=NC2=N1.O=C(CBr)c1ccccc1>>COCCOc1nc(N)c2ncn(CC(=O)c3ccccc3)c2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04795751,C[C@H]1CNC[C@@H](C)N1.Nc1c(F)c(F)c(F)c2c1c(=O)c(C(=O)O)cn2C1CC1>>C[C@H]1CN(c2c(F)c(N)c3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C[C@@H](C)N1,,CN(C)C=O,,,,test
US04118505,C#C[Mg]Br.C=CCC=C(C)C=O>>C#CC(O)C(C)=CCC=C,,C1CCOC1,,,,test
US20100029626A1,CSc1nc(O)cc(Cc2ccc3c(C(=O)O)cccc3c2)n1>>O=C(O)c1cccc2cc(Cc3cc(O)ncn3)ccc12,[Ni],CCO,O,,,test
US20030162806A1,CC(=O)NCCCCn1cnc2c(N)nc(C)c(C)c21>>Cc1nc(N)c2ncn(CCCCN)c2c1C,,Cl,,,,test
US20150274718A1,COCCl.Cc1ccc(O)cc1Br>>COCOc1ccc(C)c(Br)c1,,ClCCl,,CCN(C(C)C)C(C)C,O,test
US04888427,C=[N+]=[N-].CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O>>COC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C,,CCOC(C)=O,ClC(Cl)Cl,CCOCC,,test
US04713387,CC(=O)CC(=O)OCCOC/C(C)=C/c1ccc(Cc2cccnc2)cc1.N>>C/C(N)=C/C(=O)OCCOC/C(C)=C/c1ccc(Cc2cccnc2)cc1,,CC(C)O,,CCCCCC,,test
US20050234101A1,CC1CCNCC1.Cc1cc(CO)nc2ccc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)cc12>>Cc1cc(CN2CCC(C)CC2)nc2ccc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)cc12,,ClCCl,,O=S(Cl)Cl,c1ccncc1,test
US20110028450A1,CCOC(=O)C(=O)N(CCC#Cc1cccs1)C(C)(C)C>>CC(C)(C)N(CCC#Cc1cccs1)C(=O)C(=O)O,,C1COCCO1,O,Cl,[K+].[OH-],test
US20100160324A1,O=[N+]([O-])c1c[nH]nc1-n1cccn1>>Nc1c[nH]nc1-n1cccn1,[Pd],CCO,,,,test
US20060084640A1,C[Si](C)(C)CCOCCl.OCc1cnc(Cl)c(Cl)c1>>C[Si](C)(C)CCOCOCc1cnc(Cl)c(Cl)c1,,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US20130210804A1,COC(=O)c1cnc(OC)cc1C#C[C@H]1CC[C@H](C(=O)OC)CN1C(=O)OC(C)(C)C>>COC(=O)c1cnc(OC)cc1CC[C@H]1CC[C@H](C(=O)OC)CN1C(=O)OC(C)(C)C,[Pd],CO,,,,test
US20090137595A1,COCC(=O)Nc1cn2nc(I)ccc2n1.Nc1cccc(O)c1>>COCC(=O)Nc1cn2nc(Oc3cccc(N)c3)ccc2n1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110269954A1,O=Cc1ccc(F)cc1Cl.OCc1ccccc1>>O=Cc1ccc(OCc2ccccc2)cc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20150232481A1,CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc(C=O)nn2c1N1CCC(C)(OCCCC[C@@H](C)O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)CC1.Fc1ccc(CC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c(Br)c1>>CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)nc2cc(C=CCc3ccc(F)cc3Br)nn2c1N1CCC(C)(OCCCC[C@@H](C)O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)CC1,,C1CCOC1,,[H-].[Na+],,test
US20090186891A1,COC(=O)c1ccc(N)c(N)c1.O=Cc1c(Cl)cccc1Cl>>COC(=O)c1ccc2nc(-c3c(Cl)cccc3Cl)[nH]c2c1,,CCOC(C)=O,CS(C)=O,,,test
US20070066618A1,CC(O)c1nc2cc(C(F)(F)F)c(Cl)cc2n1-c1ccc(CCCl)cc1>>CC(=O)c1nc2cc(C(F)(F)F)c(Cl)cc2n1-c1ccc(CCCl)cc1,O=[Mn]=O,ClCCl,,,,test
US20040157886A1,Nc1ccc2[nH]ncc2c1.O=C(CCl)N1CCC(Cc2ccccc2)CC1>>O=C(CNc1ccc2[nH]ncc2c1)N1CCC(Cc2ccccc2)CC1,,CCOCC,,,,test
US20060189606A1,CCn1c(-c2ccc(NC(=O)OCCCl)cc2)c(C#N)c2ccc(OC(C)C)cc21>>CCn1c(-c2ccc(N3CCOC3=O)cc2)c(C#N)c2ccc(OC(C)C)cc21,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110294854A1,C[C@@]1(NC(=O)c2ccccc2)CC[C@@H]2CNC[C@@H]21.FC(F)(F)c1cccc(Br)n1>>C[C@@]1(NC(=O)c2ccccc2)CC[C@@H]2CN(c3cccc(C(F)(F)F)n3)C[C@@H]21,,CCO,,CCN(CC)CC,,test
US20070249670A1,C=CCc1cc(C)c(NC(=O)Nc2cc(-c3ccc(F)c(F)c3)ccc2C(=O)N[C@H](C(=O)OC)[C@@H](C)OC(C)(C)C)c(C)c1>>CCCc1cc(C)c(NC(=O)Nc2cc(-c3ccc(F)c(F)c3)ccc2C(=O)N[C@H](C(=O)OC)[C@@H](C)OC(C)(C)C)c(C)c1,[Pd],CCOC(C)=O,,[H][H],,test
US20120202785A1,C[C@H](Nc1ncnc2c1ncn2C1CCCCO1)c1nc2ccc(F)cc2n1-c1ccccc1>>C[C@H](Nc1ncnc2[nH]cnc12)c1nc2ccc(F)cc2n1-c1ccccc1,,CCOC(C)=O,,Cl,,test
US20020103253A1,COC(=O)c1sc(C(C)(C)C)cc1N.O=C(Cl)OCc1ccccc1>>COC(=O)c1sc(C(C)(C)C)cc1NC(=O)OCc1ccccc1,,O,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20130344030A1,C=CC1(C(=O)OC(C)(C)C)COC(=O)OC1>>C=CC1(C(=O)O)COC(=O)OC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050176689A1,CCOCC.Cc1cc(O)c(C(C)(C)C)cc1Br>>Cc1c(Br)cc(C(C)(C)C)c(O)c1C=O,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US04824670,COC(=O)NN.O=C(Cl)Cc1ccccc1>>COC(=O)NNC(=O)Cc1ccccc1,,O,,CC#N,,test
US20110306604A1,NC(=O)C1(N)CCCC1.O=C(Cl)c1ccccc1Cl>>NC(=O)C1(NC(=O)c2ccccc2Cl)CCCC1,,ClCCl,,CCN(CC)CC,Cl,test
US04027038,Nc1ccc2cc(S(=O)(=O)O)cc(S(=O)(=O)[O-])c2c1.O=C(Cl)c1cccc([N+](=O)[O-])c1.[Na+].[Na+]>>O=C(Nc1ccc2cc(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c2c1)c1cccc([N+](=O)[O-])c1.[Na+].[Na+],,O,,Cl,,test
US20050191238A1,Cc1ccc(CCCCO[Si](C)(C)C(C)(C)C)cc1.O=C1CCC(=O)N1Br>>CC(C)(C)[Si](C)(C)OCCCCc1ccc(CBr)cc1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US05219874,CSc1ccc(O)cc1.O=[N+]([O-])O>>CSc1ccc(O)c([N+](=O)[O-])c1,,ClCCl,,,,test
US20110021521A1,C=CC(=O)OC.FC(F)(F)Oc1ccc(-c2ccc3c(Br)nc(C(F)(F)F)n3c2)cc1>>COC(=O)/C=C/c1nc(C(F)(F)F)n2cc(-c3ccc(OC(F)(F)F)cc3)ccc12,,CN(C)C=O,,CCN(CC)CC,Cc1ccccc1P(c1ccccc1C)c1ccccc1C,test
US20090192203A1,CCO.NC(=S)CC(=O)OCc1ccccc1.O=C(CBr)c1ccc(C(F)(F)F)cc1>>CCOC(=O)Cc1nc(-c2ccc(C(F)(F)F)cc2)cs1,,CCO,,,,test
US20030073845A1,CC#N.CCOC(=O)c1ccccc1S(=O)(=O)Cl.COc1ccc(C(=O)Cl)cc1.NC1CCNC1.O>>COc1ccc(C(=O)NC2CCN(S(=O)(=O)c3ccccc3C(=O)NO)C2)cc1,CN(C)c1ccncc1,CC#N,,CCN(CC)CC,,test
US04188489,C=CC(=O)OOC(C)(CC)Nc1ccccc1.NNc1ccc(S(=O)(=O)O)cc1>>O=c1cc(Nc2ccccc2)[nH]n1-c1ccc(S(=O)(=O)O)cc1,,CC(=O)O,,CCN(CC)CC,CCO,test
US20160137649A1,CS(=O)(=O)Cl.O=Cc1ccccc1N1CCC2(CCNC2)C1>>CS(=O)(=O)N1CCC2(CCN(c3ccccc3C=O)C2)C1,,ClCCl,,CCN(CC)CC,,test
US20130064770A1,O=C1c2ccccc2C(=O)N1CCN1CCN(c2cccc(F)n2)CC1>>NCCN1CCN(c2cccc(F)n2)CC1,,CCO,,NN,O,test
US20100311730A1,CC(C)(C)OC(=O)N1CCCC(CNc2cc(Nc3cnc(C#N)cn3)ncc2-n2ccc(C(=O)O)c2)C1>>N#Cc1cnc(Nc2cc(NCC3CCCNC3)c(-n3ccc(C(=O)O)c3)cn2)cn1,,CO,,,,test
US20070244132A1,Cc1cc(Nc2ncnc3ccn(CCNC(=O)OC(C)(C)C)c23)ccc1Oc1cccc(C(F)(F)F)c1>>Cc1cc(Nc2ncnc3ccn(CCN)c23)ccc1Oc1cccc(C(F)(F)F)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06248740B1,CCOC(=O)CNC(=O)c1nc2ccc(Cl)nn2c1C.NCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1>>CCOC(=O)CNC(=O)c1nc2ccc(NCCCN3CCC(OC(c4ccccc4)c4ccccc4)CC3)nn2c1C,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US04216218,CCOC(=O)Cl.CN1CC[C@@H](Oc2ccc(Cl)cc2)[C@H](c2ccccc2)C1>>CCOC(=O)N1CC[C@@H](Oc2ccc(Cl)cc2)[C@H](c2ccccc2)C1,,c1ccccc1,,O=C([O-])[O-].[K+].[K+],,test
US20040198757A1,O=[N+]([O-])c1ccc(S(=O)(=O)NCC2CC2)cc1>>Nc1ccc(S(=O)(=O)NCC2CC2)cc1,[Pd],CCO,,,,test
US20040176410A1,CNc1ccc(C(=O)OC(C)(C)C)cc1.N#Cc1ccc(CCN2CCC3(CC2)CO3)cc1>>CN(CC1(O)CCN(CCc2ccc(C#N)cc2)CC1)c1ccc(C(=O)OC(C)(C)C)cc1,,C1CCOC1,O,CCCCCC,[Li]CCCC,test
US20080167287A1,CN(C)C(=O)Cl.C[C@H](CO)NC(=O)OC(C)(C)C>>C[C@H](COC(=O)N(C)C)NC(=O)OC(C)(C)C,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,c1ccncc1,,test
US20070060583A1,CC(C)(C)C(=O)Cl.COC(=O)c1ccc(NCC2CCCCC2)c(N)c1>>COC(=O)c1ccc2c(c1)nc(C(C)(C)C)n2CC1CCCCC1,CN(C)c1ccncc1,ClCCl,,,,test
US04515619,CCC(=O)Cl.O=C(Nc1cnns1)N(O)c1ccccc1>>CCC(=O)ON(C(=O)Nc1cnns1)c1ccccc1,,C1CCOC1,,CCN(CC)CC,,test
US20130012491A1,CCOC(=O)C1CCNCC1.CCc1c(C=O)cccc1-c1cnc(-c2ccc(OC(C)C)c(C(F)(F)F)c2)nc1>>CCOC(=O)C1CCN(Cc2cccc(-c3cnc(-c4ccc(OC(C)C)c(C(F)(F)F)c4)nc3)c2CC)CC1,,CCO,,CC(=O)O,,test
US20050143381A1,NNc1nncc(-c2ccc(Cl)cc2)c1Cl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=c1[nH]nc2c(Cl)c(-c3ccc(Cl)cc3)cnn12,,C1CCOC1,,,,test
US20050075365A1,Cc1ccc(C=O)cc1.Clc1ccccc1-c1nnc2ccc(Br)cn12>>Cc1ccc(C(O)c2ccc3nnc(-c4ccccc4Cl)n3c2)cc1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20030092677A1,CC(C)c1ccc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])c1>>CC(C)c1ccc(NC(=O)OC(C)(C)C)c(N)c1,[Pd],,,,,test
US20100069368A1,CC(O)(COS(C)(=O)=O)c1cnc(N2CCN(c3nnc(Cc4ccccc4)c4ccccc34)CC2)cn1.OC1CCNCC1>>CC(O)(CN1CCC(O)CC1)c1cnc(N2CCN(c3nnc(Cc4ccccc4)c4ccccc34)CC2)cn1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20020103229A1,Nc1ccc2[nH]nc(-c3ccccc3)c2c1.O=C(Cl)c1ccccc1>>O=C(Nc1ccc2[nH]nc(-c3ccccc3)c2c1)c1ccccc1,CCN(CC)CC,CC#N,,,,test
US03943124,C[C@]12CC=CC[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)O)[C@@]3(C)CC(=O)[C@@H]12.O=C(Cl)C(=O)Cl>>C[C@]12CC=CC[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cl)[C@@]3(C)CC(=O)[C@@H]12,,c1ccccc1,,,,test
US20110065706A1,C[C@@H]1CN(C#N)CCN1C(=O)OC(C)(C)C.NO>>C[C@@H]1CN(C(=N)NO)CCN1C(=O)OC(C)(C)C,,CN(C)C=O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US05143920,O=[N+]([O-])c1cc(F)c(O)c(F)c1>>Nc1cc(F)c(O)c(F)c1,[Pd],CCO,,[H][H],,test
US20090286782A1,Nc1cccc(F)n1.O=Cc1ccccc1Cl>>Fc1cccc(NCc2ccccc2Cl)n1,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20020025296A1,CI.C[Si](C)(C)/C=C/c1cn([C@@H]2O[C@H](CO)[C@@H](OC(=O)c3cccnc3)[C@H]2F)c(=O)[nH]c1=O>>C[n+]1cccc(C(=O)O[C@@H]2[C@@H](CO)O[C@@H](n3cc(/C=C/[Si](C)(C)C)c(=O)[nH]c3=O)[C@@H]2F)c1.[I-],,CC(C)=O,,,,test
US04678498,COc1ccc(C)cc1S(=O)(=O)NC(C)(C)C.O=C1CCC(=O)N1Br>>COc1ccc(CBr)cc1S(=O)(=O)NC(C)(C)C,CC(C)(C#N)N=NC(C)(C)C#N,ClCCl,,,,test
US20070197621A1,CCI.O=C(O)c1cccc2cccc(Br)c12>>CCOC(=O)c1cccc2cccc(Br)c12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100197715A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CN1CC(N)(c2ccccc2)CCC1=O>>CN1CC(NC(=O)OC(C)(C)C)(c2ccccc2)CCC1=O,,C1CCOC1,,CCN(CC)CC,O,test
US20080076800A1,COCC(C)N.N#Cc1ccc(Br)cc1F>>COCC(C)Nc1cc(Br)ccc1C#N,,CCOC(C)=O,,CCN(C(C)C)C(C)C,CS(C)=O,test
US20070010511A1,COCCCN1C(=O)COc2ccc(COC3CN(C(=O)OC(C)(C)C)CCC3c3ccc(C(=O)O)cc3)cc21.O=C(Cl)C(=O)Cl>>COCCCN1C(=O)COc2ccc(COC3CN(C(=O)OC(C)(C)C)CCC3c3ccc(C(=O)Cl)cc3)cc21,CN(C)C=O,ClCCl,,,,test
US20080293701A1,CC(C)(N)c1ccccc1.ClCCl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)(NC(=O)Cl)c1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04565870,CCOC(CCCCl)OCC.Cl.NCCc1c[nH]c2ccccc12>>Cl.ClCCCC1NCCc2c1[nH]c1ccccc21,,CC(C)O,,,,test
US20090048252A1,CC(C)(C)[Si](C)(C)OCc1nc2cc(C=O)ccc2[nH]1.O=C1CS/C(=N\c2c(Cl)cccc2Cl)N1>>CC(C)(C)[Si](C)(C)OCc1nc2cc(/C=C3\S/C(=N\c4c(Cl)cccc4Cl)NC3=O)ccc2[nH]1,,CCO,,C1CCNCC1,Cl,test
US04442300,CC(C)(C)C(=O)Oc1ccc(C(=O)Oc2cc(OC(=O)c3ccc(OC(=O)C(C)(C)C)cc3)cc(C(=O)CNC3CCC3)c2)cc1.O=S(=O)(O)O>>CC(C)(C)C(=O)Oc1ccc(C(=O)Oc2cc(OC(=O)c3ccc(OC(=O)C(C)(C)C)cc3)cc(C(CNC3CCC3)OS(=O)(=O)O)c2)cc1,[Pd],CCO,,Cl,,test
US06215004B1,CCCC(=O)OCC(OCC)OCC.O=C(O)CS>>CCCC(=O)OCC1OC(=O)CS1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20100068197A1,COc1ccc(N(C)c2nc(CNC(=O)[C@H](CC(N)=O)NC(=O)OC(C)(C)C)nc3ccccc23)cc1>>COc1ccc(N(C)c2nc(CNC(=O)[C@@H](N)CC(N)=O)nc3ccccc23)cc1,,CO,,,,test
US05405861,CS(=O)(=O)Cl.C[C@H](O)[C@@](O)(Cn1cncn1)c1ccc(F)cc1F>>C[C@H](OS(C)(=O)=O)[C@@](O)(Cn1cncn1)c1ccc(F)cc1F,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20110312905A1,CC1(C)OB(c2ccc(CBr)cc2)OC1(C)C.[O-][n+]1ccccc1O>>CC1(C)OB(c2ccc(COn3ccccc3=O)cc2)OC1(C)C,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100009969A1,C1CCNCC1.CC1CCCN1CCCOc1ccc(-c2nc3c(s2)CCCC3O)cc1>>CC1CCCN1CCCOc1ccc(-c2nc3c(s2)CCCC3N2CCCCC2)cc1,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20020045777A1,CCCNC.CN(C(=O)Oc1ccc(Cl)cc1)[C@@H]1CC[C@@H](/C=C/CCl)CC1>>CCCN(C)C/C=C/[C@@H]1CC[C@@H](N(C)C(=O)Oc2ccc(Cl)cc2)CC1,,CO,,,,test
US20030033089A1,CC(C)n1c(=O)nc(-c2ccc(O)c(N)c2)c2cc3c(cc21)OCO3.CCOC(OCC)OCC>>CC(C)N1C(=O)NC(c2ccc3ocnc3c2)c2cc3c(cc21)OCO3,,CCOC(C)=O,,,,test
US20130102776A1,COC(Cl)Cl.COc1cc(O)c(C(C)=O)cc1OC>>COc1cc(C(C)=O)c(O)c(C=O)c1OC,Cl[Ti](Cl)(Cl)Cl,ClCCl,,,,test
US20060211603A1,C[C@H]1[C@@H](c2ccccc2)OC(=O)N1CC(=O)OCc1ccccc1>>C[C@H]1[C@@H](c2ccccc2)OC(=O)N1CC(=O)O,[Pd],CCOC(C)=O,,,,test
US20160007601A1,C[C@@H]1OC(=O)[C@@H](NC(=O)OC(C)(C)C)COC[C@H](Cc2ccccc2)[C@H]1Cc1ccccc1.Cl>>C[C@@H]1OC(=O)[C@@H]([NH3+])COC[C@H](Cc2ccccc2)[C@H]1Cc1ccccc1.[Cl-],,ClCCl,,,,test
US20130059834A1,COC(=O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ncc(-c3nn(C)c4ccc(OCCCC(C)(C)[N+](=O)[O-])cc34)nc12>>COC(=O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ncc(-c3nn(C)c4ccc(OCCCC(C)(C)N)cc34)nc12,[Pd],CO,,,,test
US20020035272A1,BrCc1ccc(Br)cc1.Cc1ccsc1C>>Cc1cc(Cc2ccc(Br)cc2)sc1C,,C1CCOC1,,,,test
US04958026,ClCc1ccccc1.O=Cc1ccc(O)c([N+](=O)[O-])c1>>O=Cc1ccc(OCc2ccccc2)c([N+](=O)[O-])c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20090042726A1,BrP(Br)Br.CCn1cc(CO)c(C(F)(F)F)n1>>CCn1cc(CBr)c(C(F)(F)F)n1,,CCOCC,,,,test
US20120316207A1,CC(=O)OC[C@H]1O[C@@H](OC(C)=O)[C@H](N=C=S)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.CN>>CNC(=S)N[C@H]1[C@H](OC(C)=O)O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O,,CC#N,,Cl,,test
US20060194780A1,CC(C)(C)OC(=O)N1C2CCC1CC(C(=O)O)(C1CCCCC1)C2>>CC(C)(C)OC(=O)N1C2CCC1CC(CO)(C1CCCCC1)C2,,C1CCOC1,,B,CSC,test
US04056540,CN(C)CCCNC(=O)[C@H]1Oc2ccc(Cl)cc2[C@H](c2ccccc2)O1.Cl>>CN(C)CCCNC(=O)[C@H]1Oc2ccccc2[C@H](c2ccccc2)O1.Cl,[Pd],CCO,,CCN(CC)CC,,test
US20100210619A1,COc1cc(NS(C)(=O)=O)ccc1N.O=C(O)c1cc(NC2CCCCC2)ncn1>>COc1cc(NS(C)(=O)=O)ccc1NC(=O)c1cc(NC2CCCCC2)ncn1,,ClCCl,,,,test
US20090264431A1,CC(C)(C)OC(=O)N1C[C@H](N=[N+]=[N-])C[C@@H]1CC#N>>CC(C)(C)OC(=O)N1C[C@H](N)C[C@@H]1CC#N,[Pd],CO,,,,test
US05112998,COC(OC)C(C)[C@H]1CC[C@H]2[C@@H]3[C@@H]4O[C@]45OC4=C5[C@](C)(CCC4=O)[C@H]3CC[C@]12C>>COC(OC)C(C)[C@H]1CC[C@H]2[C@@H]3[C@@H]4O[C@]45OC4=C5[C@](C)(CC[C@@H]4O)[C@H]3CC[C@]12C,,C1CCOC1,O,Cl,[BH4-].[Na+],test
US20120165347A1,CC(C)(C)S(=O)N=C1c2cc(Br)ccc2CC12CCC1(CC2)OCCO1>>N=C1c2cc(Br)ccc2CC12CCC(=O)CC2,,C1COCCO1,,Cl,,test
US20050245529A1,C/C(=C\[C@H](C)NCC1CC1)c1ccc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)cc1.CCCBr>>CCCN(CC1CC1)[C@@H](C)/C=C(\C)c1ccc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)cc1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,O=C([O-])O.[Na+],test
US06265409B1,CC(C)(C)[Si](C)(C)Cl.O[C@H](CCc1cccnc1)COc1ccc(Br)cc1>>CC(C)(C)[Si](C)(C)O[C@H](CCc1cccnc1)COc1ccc(Br)cc1,,ClCCl,,c1c[nH]cn1,,test
US06057369,COC(=O)C(C)(C)C(CCCCc1ccccc1)OS(C)(=O)=O.COc1ccc(S)cc1>>COC(=O)C(C)(C)C(CCCCc1ccccc1)Sc1ccc(OC)cc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20030073731A1,CC(=O)OC(C)=O.O=[N+]([O-])c1cc(OCc2ccccc2)c2ccccc2c1CCO>>CC(=O)OCCc1c([N+](=O)[O-])cc(OCc2ccccc2)c2ccccc12,,c1ccncc1,,,,test
US20100240669A1,C/C(=N/O)c1ccc(Nc2ccccc2C(F)(F)F)cn1>>CC(N)c1ccc(Nc2ccccc2C(F)(F)F)cn1,[Ni],N,,[H][H],,test
US20160264552A1,COC(=O)C1CC(C(=O)OC)CN(C(=O)OCc2ccccc2)C1>>COC(=O)C1CC(C(=O)O)CN(C(=O)OCc2ccccc2)C1,,CO,O,[Li]O,,test
US20070066624A1,CC(C)(C)N1C[C@@H](c2ccccc2)N(C2CCN(Cc3ccc(Oc4ccc(C#N)cc4)nc3)CC2)C1=O.[N-]=[N+]=[N-].[NH4+]>>CC(C)(C)N1C[C@@H](c2ccccc2)N(C2CCN(Cc3ccc(Oc4ccc(-c5nn[nH]n5)cc4)nc3)CC2)C1=O,,CN(C)C=O,,[Cl-].[Na+],,test
US20110160256A1,Cn1nccc1-c1csc(C(=O)NC(CNC(=O)OC(C)(C)C)Cc2ccccc2)n1>>Cn1nccc1-c1csc(C(=O)NC(CN)Cc2ccccc2)n1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20100311734A1,O=C(O)Cc1ccccc1Sc1ccc(F)cc1>>O=C1Cc2ccccc2Sc2ccc(F)cc21,,CCOC(C)=O,,,,test
US20130274299A1,CC(N)=NO.CCOC(=O)[C@]12C[C@H]1CN(C(=O)OC(C)(C)C)C2>>Cc1noc([C@]23C[C@H]2CN(C(=O)OC(C)(C)C)C3)n1,,CC1CCCO1,,C[O-].[Na+],,test
US20080275054A1,COc1ccc(-n2ncc3c(Cl)ncnc32)cc1.Nc1cc(C(=O)Nc2cccc(C(F)(F)F)c2)ccc1Cl>>COc1ccc(-n2ncc3c(Nc4cc(C(=O)Nc5cccc(C(F)(F)F)c5)ccc4Cl)ncnc32)cc1,,CC(C)(C)O,,,,test
US20060270692A1,CN1CCC(COc2cc3ncnc(O)c3cc2OC(=O)c2ccccc2)CC1.O=S(Cl)Cl>>CN1CCC(COc2cc3ncnc(Cl)c3cc2OC(=O)c2ccccc2)CC1,,CN(C)C=O,,,,test
US20060281920A1,CCCN(C)C1CCN(C(=O)OC(C)(C)C)CC1>>CCCN(C)C1CCNCC1,,CCOC(C)=O,,Cl,,test
US20070082912A1,CCOC(=O)c1cccc(N)c1.COc1ccc(COc2ccc(S(C)(=O)=O)cc2C(=O)CCC(C)=O)cc1>>CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(S(C)(=O)=O)ccc2O)c1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20140058103A1,Cn1c(Br)nc2c(Cl)ncnc21.O=c1[nH]c2ccccc2n1C1CCNCC1>>Cn1c(Br)nc2c(N3CCC(n4c(=O)[nH]c5ccccc54)CC3)ncnc21,,CCO,,,,test
US20130272961A1,C#C[Sn](CCCC)(CCCC)CCCC.[N-]=[N+]=NCCNC(=N)N>>CCCC[Sn](CCCC)(CCCC)c1cn(CCNC(=N)N)nn1,[Cu]I,C1CCOC1,,,,test
US08691827B2,CC(C)(C)OC(=O)N1CCc2nc(Cl)nc(Cl)c2C1.NCCc1ccccn1>>CC(C)(C)OC(=O)N1CCc2nc(Cl)nc(NCCc3ccccn3)c2C1,,CN(C)C=O,,CCOC(C)=O,O,test
US20160237090A1,C[C@H]1Cn2ncc(I)c2CN1C(=O)OC(C)(C)C.O=C1NCC(c2ccccc2)N1>>C[C@H]1Cn2ncc(N3CC(c4ccccc4)NC3=O)c2CN1C(=O)OC(C)(C)C,[Cu]I,C1COCCO1,,CN[C@@H]1CCCC[C@H]1NC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20070161662A1,Cc1cccc(C)c1-n1ncc(C#N)c1N.OO>>Cc1cccc(C)c1-n1ncc(C(N)=O)c1N,,CCO,ClCCl,N,,test
US20090111859A1,COc1ccc(F)c(-c2cc(CO)ccc2C2CC2)c1.O=S(Cl)Cl>>COc1ccc(F)c(-c2cc(CCl)ccc2C2CC2)c1,,ClCCl,,,,test
US20090093454A1,C1CSCCN1.Fc1cccc2nc(CN3CCC[C@H]4CCc5cccnc5[C@H]43)cn12>>c1cnc2c(c1)CC[C@@H]1CCCN(Cc3cn4c(N5CCSCC5)cccc4n3)[C@H]21,,CS(C)=O,,,,test
US20020161014A1,Cc1cccc2nc(CCl)n(-c3ccccc3Cl)c(=O)c12.Nc1ncnc2nc[nH]c12>>Cc1cccc2nc(Cn3cnc4c(N)ncnc43)n(-c3ccccc3Cl)c(=O)c12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080280924A1,CC(C)(C)NS(=O)(=O)c1cccc(-c2cccc(-c3nc(-c4ccc(Cl)s4)cc(C(F)(F)F)n3)c2)c1>>NS(=O)(=O)c1cccc(-c2cccc(-c3nc(-c4ccc(Cl)s4)cc(C(F)(F)F)n3)c2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05846982,CN1CCC(=O)CC1.Clc1ccc2sccc2c1>>CN1CCC(O)(c2cc3cc(Cl)ccc3s2)CC1,,C1CCOC1,,[Li]CCCC,,test
US20050250822A1,Cc1cc(C(C(Br)Br)C(F)(F)F)ccc1NC(=O)OC(C)(C)C.N#CCC#N>>Cc1cc(C2(C(F)(F)F)CC2(C#N)C#N)ccc1NC(=O)OC(C)(C)C,,Cc1ccccc1,,CC(C)(C)[O-].[K+],,test
US20100197654A1,C[C@@]1(C(=O)Nc2ccc(F)nc2)CCCN1.Clc1nc(Cl)nc(Nc2cc(C3CC3)n[nH]2)n1>>C[C@@]1(C(=O)Nc2ccc(F)nc2)CCCN1c1nc(Cl)nc(Nc2cc(C3CC3)n[nH]2)n1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US04010178,CCOC(=O)C(=NOC(=O)OC(C)(C)C)C(=O)OCC.C[C@H](N)C(=O)O>>C[C@H](NC(=O)OC(C)(C)C)C(=O)O,,CC(C)(C)O,O,CCN(CC)CC,,test
US20020183320A1,Nc1nc[nH]n1.O=Cc1cccc(Cl)c1Cl.[C-]#[N+]C(C)(C)C>>CC(C)(C)Nc1c(-c2cccc(Cl)c2Cl)nc2nc[nH]n12,,[O-][Cl+3]([O-])([O-])O,,,,test
US06235771B1,COC(=O)C1=Cc2cc(-c3ccc(N4CCCCC4)cc3)ccc2S(=O)(=O)CC1>>O=C(O)C1=Cc2cc(-c3ccc(N4CCCCC4)cc3)ccc2S(=O)(=O)CC1,,Cl,,,,test
US20090203737A1,Cc1c[nH]c(-c2nc([C@H]3CCCN(C(=O)OC(C)(C)C)C3)no2)c1.Cl>>Cc1c[nH]c(-c2nc([C@H]3CCCNC3)no2)c1.Cl,,Cl,,ClCCl,,test
US20070287842A1,CC(C)O.CCO.Nc1sc(N)c(C(=O)[O-])c1C(=O)[O-].O=Cc1ccc(-c2cccs2)s1.O=Cc1cccs1>>CCOC(=O)c1c(N=Cc2cccs2)sc(N=Cc2ccc(-c3cccs3)s2)c1C(=O)OCC,,CC(C)O,,O=C(O)C(F)(F)F,,test
US20040138065A1,N#CC(C#N)Cc1ccccc1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>N#CC(C#N)(Cc1ccccc1)CC(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20020016368A1,Br.CC(C)Cc1ccc(CO)cc1>>CC(C)Cc1ccc(CBr)cc1,,CCOCC,,,,test
US20090036453A1,CCCC=Cc1c(-c2ccc(OC(F)F)c(OC3CC3)c2)n(COCC[Si](C)(C)C)c2cnn(COCC[Si](C)(C)C)c(=O)c12>>CCCCCc1c(-c2ccc(OC(F)F)c(OC3CC3)c2)n(COCC[Si](C)(C)C)c2cnn(COCC[Si](C)(C)C)c(=O)c12,O=[Pt],CCO,,[H][H],,test
US20040121965A1,CCOC(=O)/C(C)=C/[C@H](C(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](N(C)C(=O)OC(C)(C)C)C(C)(C)c1ccccc1)[C@H](C)OC>>CO[C@@H](C)[C@H](NC(=O)[C@@H](N(C)C(=O)OC(C)(C)C)C(C)(C)c1ccccc1)C(=O)N(C)[C@H](/C=C(\C)C(=O)O)C(C)C,,CO,,O,[Li+].[OH-],test
US20060046985A1,CON(C)C1CCn2c(nc(C(=O)NCc3ccc(F)cc3)c(O)c2=O)C1>>CNC1CCn2c(nc(C(=O)NCc3ccc(F)cc3)c(O)c2=O)C1,[Zn],CC(=O)O,O,,,test
US04520196,Cn1c(S)nc2ccccc21.O=C(O)C(Br)c1ccc(Cl)cc1>>Cn1c(SC(C(=O)O)c2ccc(Cl)cc2)nc2ccccc21,,CCN(CC)CC,,ClCCl,,test
US05576322,N#Cc1ccc2nc(Cl)nc(NCc3ccc4c(c3)OCO4)c2c1.OC1CCNCC1>>N#Cc1ccc2nc(N3CCC(O)CC3)nc(NCc3ccc4c(c3)OCO4)c2c1,,CCOC(C)=O,,CN(C)C=O,O,test
US20050124656A1,Cc1ccc(-c2ccc(C(=O)OC(C)(C)C)cc2)cc1.O=C1CCC(=O)N1Br>>CC(C)(C)OC(=O)c1ccc(-c2ccc(CBr)cc2)cc1,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US20050075328A1,O=C(Cl)c1ccc(-c2ccccc2)cc1.c1cnc2c(c1)NCc1cccn1C2>>O=C(c1ccc(-c2ccccc2)cc1)N1Cc2cccn2Cc2ncccc21,,Cc1ccccc1,,CCN(CC)CC,,test
US20140088079A1,C=CCSc1c(Br)cc(C#N)c(Cl)c1CC=C.CCO.CCOC(C)=O>>CC=CSc1c(Br)cc(C(=O)OC)c(Cl)c1C=CC,,CCO,O,Cl,[Na+].[OH-],test
US20120190649A1,COC(=O)C1CN(Cc2ccc3c(C)c(O[C@@H]4CC[C@@H](C(C)(C)C)CC4)ccc3c2)C1>>Cc1c(O[C@@H]2CC[C@@H](C(C)(C)C)CC2)ccc2cc(CN3CC(C(=O)O)C3)ccc12,,CCO,,Cl,[Na+].[OH-],test
US04477464,N[C@@H](CSc1ccccc1[N+](=O)[O-])C(=O)O.O=C(Cl)OCc1ccccc1>>O=C(N[C@@H](CSc1ccccc1[N+](=O)[O-])C(=O)O)OCc1ccccc1,,[Na+],[OH-],,,test
US05153214,CC1CC(CCCCO[Si](C)(C)C(C)(C)C)CCOC1=O.CI>>CC1(C)CC(CCCCO[Si](C)(C)C(C)(C)C)CCOC1=O,,C1CCOC1,CCCCCC,CC(C)NC(C)C,[Li]CCCC,test
US20160176850A1,O=C(O)c1cccc(Br)n1.O=S(Cl)Cl>>O=C(Cl)c1cccc(Br)n1,,Cc1ccccc1,,CO,ClCCl,test
US05639752,CN(C)CCc1c[nH]c2ccc(N)cc12.Clc1ncccn1>>CN(C)CCc1c[nH]c2ccc(Nc3ncccn3)cc12,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US20120277224A1,CC1(C)OC(=O)CC(=O)O1.CS(=O)(=O)c1ccc(C(=O)O)cc1>>CC1(C)OC(=O)C(C(=O)c2ccc(S(C)(=O)=O)cc2)C(=O)O1,CN(C)c1ccncc1,ClCCl,ClCCl,CCN=C=NCCCN(C)C,Cl,test
US20130023541A1,CC(C)OC(=O)c1cccnc1N1CCN(Cc2ccc(C=O)cc2)CC1.NCc1ccccc1>>CC(C)OC(=O)c1cccnc1N1CCN(Cc2ccc(CNCc3ccccc3)cc2)CC1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20030187068A1,CCO.CCOC(=O)C(=Cc1ccc(OC)c([N+](=O)[O-])c1)CC>>CCOC(=O)C(Cc1ccc(OC)c(N)c1)OC,[Pd],CCO,,C1CCOC1,,test
US20130172323A1,CCC(O)C(=O)c1ccc2nc(-c3ccccc3)oc2c1.CCOC(=O)NN>>CCC1OC(=O)NN=C1c1ccc2nc(-c3ccccc3)oc2c1,Cl,CCO,,[Na],,test
US20090233960A1,COC(=O)c1ccc(C(C)N)cc1.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1ccc(C(C)NC(=O)C(F)(F)F)cc1,,ClCCl,,CCN(C(C)C)C(C)C,Cl,test
US06380197B1,CCCN(C=C1C=CC(C(=O)O)=CC1)CCC.O=C(Cl)C(=O)Cl>>CCCN(C=C1C=CC(C(=O)Cl)=CC1)CCC,,ClCCl,,CN(C)C=O,Cl,test
US20100280268A1,COC(=O)c1cc(Oc2ccc(N)c(OC)c2)ccc1NS(=O)(=O)c1ccc(C)cc1.Cc1ccc(S(=O)(=O)Cl)cc1>>COC(=O)c1cc(Oc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(OC)c2)ccc1NS(=O)(=O)c1ccc(C)cc1,,ClCCl,,c1ccncc1,,test
US04898871,COc1ccc2ccc(N3C(=O)c4ccccc4C3O)nc2n1.ClCc1cccnc1>>COc1ccc2ccc(N3C(=O)c4ccccc4C3OCc3cccnc3)nc2n1,,CN(C)C=O,Cc1ccccc1,[H-].[Na+],,test
US20160229872A1,CC(C)CCON=O.N#CCc1ccc(F)cc1>>N#CC(=NO)c1ccc(F)cc1,,CCO,,C,C[O-].[Na+],test
US04272437,COC(=O)C(CCI)N=[N+]=[N-].[C-]#N>>COC(=O)C(CCC#N)N=[N+]=[N-],,CS(C)=O,,O,,test
US20100093757A1,Cc1ccc(F)cc1-n1ncc2c(O[C@@H](COCCO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)C(=O)Nc3ccc(Cl)cn3)ncnc21>>Cc1ccc(F)cc1-n1ncc2c(O[C@@H](COCCO)C(=O)Nc3ccc(Cl)cn3)ncnc21,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040053908A1,CN(C)C=O.N#Cc1cc2c(Oc3ccc(NC(=O)Oc4ccccc4)c(Cl)c3)ccnc2cc1OCc1ccccc1>>CNC(=O)Nc1ccc(Oc2ccnc3cc(OCc4ccccc4)c(C#N)cc23)cc1Cl,,O,,C1CCOC1,,test
US20100311980A1,CNC(=O)c1cc(Oc2ccc(N(Cl)C(=O)C(Cl)(Cl)Cl)cc2)ccn1.Nc1ccc(Cl)c(C(F)(F)F)c1>>CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1,,CCOC(C)=O,CN(C)C=O,C1CCC2=NCCCN2CC1,,test
US20120035208A1,CS(=O)(=O)c1ccc(O)cc1.Cn1ncc2c(Cl)cc(-c3cccc4[nH]ncc34)nc21>>Cn1ncc2c(Oc3ccc(S(C)(=O)=O)cc3)cc(-c3cccc4[nH]ncc34)nc21,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100029710A1,Br[Mg]c1ccccc1.CCc1nc2c(C)cc(C=O)nc2n1[C@H]1CCc2cc(Br)ccc21>>CCc1nc2c(C)cc(C(O)c3ccccc3)nc2n1[C@H]1CCc2cc(Br)ccc21,,C1CCOC1,,,,test
US20090264448A1,CC(=O)N(C)c1cc(C(=O)C=CN(C)C)ccc1Cl.N#Cc1cn[nH]c1N>>CC(=O)N(C)c1cc(-c2ccnc3c(C#N)cnn23)ccc1Cl,,CC(=O)O,,CCOC(C)=O,,test
US20140154179A1,CC(C)(C)OC(=O)N1CC[C@H](N)C1.CCOC(=O)c1ncc2cc(Cl)ccc2n1>>CC(C)(C)OC(=O)N1CC[C@H](NC(=O)c2ncc3cc(Cl)ccc3n2)C1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,,test
US20060148858A1,CCCCI.CCOC(=O)CCc1ccc(OCCCc2cn(-c3ccc(C(F)(F)F)cn3)nc2OCC)c(O)c1>>CCCCOc1cc(CCC(=O)O)ccc1OCCCc1cn(-c2ccc(C(F)(F)F)cn2)nc1OCC,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140094462A1,C[C@@H]1[C@@H](c2ccccc2)OC(=O)CCC=CC[C@@H](CC(=O)OC(C)(C)C)C(=O)N1C>>C[C@@H]1[C@@H](c2ccccc2)OC(=O)CCC=CC[C@@H](CC(=O)O)C(=O)N1C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20050282888A1,C#CCOc1ccc(CCC(=O)Cl)cc1OC.Cc1ccc(CN)cc1>>C#CCOc1ccc(CCC(=O)NCc2ccc(C)cc2)cc1OC,,O,,C1CCOC1,CCN(CC)CC,test
US20140275083A1,CC(OC(C)(C)C)[C@H](NC(=O)OCc1ccccc1)C(=O)O>>CC(OC(C)(C)C)[C@@H](CO)NC(=O)OCc1ccccc1,,C1CCOC1,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20050001200A1,OCCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F.Oc1ccc(Br)cc1>>FC(F)(F)C(F)(F)C(F)(F)C(F)(F)CCCCOc1ccc(Br)cc1,,CCOCC,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060160850A1,CC(C)(C)OC(=O)NC1Cc2cc(Br)ccc2N(Cc2ccccc2)C1.OB(O)c1ccc(F)cc1>>CC(C)(C)OC(=O)NC1Cc2cc(-c3ccc(F)cc3)ccc2N(Cc2ccccc2)C1,,C1CCOC1,CO,N#N,O=C([O-])[O-].[K+].[K+],test
US20060074127A1,CC(=O)Oc1ccc2c(=O)c(-c3ccc(O)cc3)coc2c1C>>CC(=O)Oc1ccc2c(c1C)OCC(c1ccc(O)cc1)C2=O,,CCOC(C)=O,,,,test
US20090062324A1,CCC(=O)N1CCCC2C(=O)c3c(c(Br)cc4c3OCO4)CC21>>CCCN1CCC[C@@H]2Cc3c(ccc4c3OCO4)C[C@@H]21,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20030078251A1,CCOC(=O)c1cccc2c(NC(=O)C[C@H]3O[C@H](c4cccc(OC)c4OC)c4cc(Cl)ccc4N(CC(C)(C)COC(C)=O)C3=O)cccc12>>COc1cccc([C@H]2O[C@H](CC(=O)Nc3cccc4c(C(=O)O)cccc34)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC,,O,,CCO,[Na+].[OH-],test
US05414130,CO.O.O=[N+]([O-])c1cc([N+](=O)[O-])c(Cl)cc1Cl>>COc1cc(O)c([N+](=O)[O-])cc1[N+](=O)[O-],,O,,Cl,[Na+].[OH-],test
US20100152257A1,Cc1noc(-c2ccc(Br)cc2)c1NC(=O)OC(C)c1ccccc1Cl.O=C(O)c1cccc(B(O)O)c1>>Cc1noc(-c2ccc(-c3cccc(C(=O)O)c3)cc2)c1NC(=O)OC(C)c1ccccc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[K+].[K+],,test
US20090131458A1,CCCCCNc1nc(N)c2nc(OC)n(CC3CCOCC3)c2n1>>CCCCCNc1nc(N)c2[nH]c(=O)n(CC3CCOCC3)c2n1,,C1COCCO1,CO,Cl,[Na+].[OH-],test
US20140330009A1,CC(c1ccc(F)cc1)n1nc(-c2ccc(F)cc2)c2c1CCNC2.CS(=O)(=O)Cl>>C[C@H](c1ccc(F)cc1)n1nc(-c2ccc(F)cc2)c2c1CCN(S(C)(=O)=O)C2,,ClCCl,,CCN(CC)CC,,test
US20070112015A1,CO.Nc1c(C(=O)O)cccc1[N+](=O)[O-]>>COC(=O)c1cccc([N+](=O)[O-])c1N,,CO,,C[Si](C)(C)C=[N+]=[N-],,test
US20090137580A1,Cn1ccc2ncnc(Oc3ccc(N)cc3)c21.Nc1nc(C(F)(F)F)co1.O=C(Cl)Oc1ccccc1>>Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4nc(C(F)(F)F)co4)cc3)c21,,CC(=O)N(C)C,,c1ccncc1,,test
US04933333,COc1ccc(CC(Cc2ccc(OC)cc2)N2C(=O)C(C(C)OC(=O)OCc3ccc([N+](=O)[O-])cc3)C2CC(=O)C(=[N+]=[N-])C(=O)OCc2ccc([N+](=O)[O-])cc2)cc1>>CC(OC(=O)OCc1ccc([N+](=O)[O-])cc1)C1C(=O)NC1CC(=O)C(=[N+]=[N-])C(=O)OCc1ccc([N+](=O)[O-])cc1,,CC#N,O,,,test
US04230707,COC(=O)c1sc(C)cc1N.NC(=O)c1ccc(Cl)nc1>>Cc1cc2nc3ccc(C(N)=O)cn3c(=O)c2s1,,ClC(Cl)Cl,,,,test
US20150225389A1,CCCCCCOC(=O)Cl.CCOC(=O)[C@@H]1[C@@H](Cc2ccnc(N)c2)C(=O)N1C(=O)N[C@H](C)c1ccccc1>>CCCCCCOC(=O)Nc1cc(C[C@H]2C(=O)N(C(=O)N[C@H](C)c3ccccc3)[C@@H]2C(=O)OCC)ccn1,,ClCCl,O,c1ccncc1,,test
US20090054405A1,CC(=O)Nc1nc2ccc(B3OC(C)(C)C(C)(C)O3)cc2s1.CN(c1cncc(Br)c1)S(=O)(=O)c1ccc(C(F)(F)F)cc1>>CC(=O)Nc1nc2ccc(-c3cncc(N(C)S(=O)(=O)c4ccc(C(F)(F)F)cc4)c3)cc2s1,[Pd],C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20120245161A1,CC(C)(C)OC(=O)NCc1ccc(C(F)(F)F)c(C2=CCN(C(=O)OCc3ccccc3)CC2)c1>>CC(C)(C)OC(=O)NCc1ccc(C(F)(F)F)c(C2=CCNCC2)c1,[Pd],C1CCOC1,,,,test
US06248738B1,O=S(=O)(Sc1ccccc1)c1ccccc1.O=c1[nH]cc(Cl)c2ccc(Br)cc12>>O=c1[nH]cc(Cl)c2ccc(Sc3ccccc3)cc12,,C1CCOC1,O,[Li]CCCC,[H-].[Na+],test
US20120142714A1,CC(C)[Si](Oc1ccc(Br)nc1)(C(C)C)C(C)C.COCOc1ccc(CC(C)=O)c(Br)c1>>COCOc1ccc(CC(C)(O)c2ccc(O[Si](C(C)C)(C(C)C)C(C)C)cn2)c(Br)c1,,CCOCC,CCOCC,[Li]CCCC,[Cl-].[NH4+],test
US20140314669A1,COC(=O)CC(NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1cc(F)cc(-c2ccc(O)cc2)c1.Cc1ccc(S(=O)(=O)OCCOS(=O)(=O)c2ccc(C)cc2)cc1>>COC(=O)CC(NC(=O)[C@@H]1CCCN(C(=O)CCC2CCN(C(=O)OC(C)(C)C)CC2)C1)c1cc(F)cc(-c2ccc(OCCOS(=O)(=O)c3ccc(C)cc3)cc2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20130261116A1,CNC(=O)c1ccc(-c2ccc3nnn(Cc4c(F)ccc(F)c4Cl)c3n2)cc1F.CNC(=O)c1ccc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)cc1F>>CC(C)(O)c1ccc(-c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)cc1F,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[K+].[K+],test
US20090036492A1,COc1cc(O)c2c(c1C(N)=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C.Cc1c(C=O)ccc(NC(=O)c2ccccc2)c1C>>COc1cc(O)c2c(c1C(=O)NCc1ccc(NC(=O)c3ccccc3)c(C)c1C)OC1=CC(O)=C(C(C)=O)C(=O)[C@]12C,,CC#N,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US06331538B1,C1CCNC1.O=c1[nH]c2cc(F)c(F)cc2c(=O)n1OCc1ccccc1>>O=c1[nH]c2cc(N3CCCC3)c(F)cc2c(=O)n1OCc1ccccc1,,CC#N,,CCN(CC)CC,,test
US20100099681A1,CC1(C)OB(c2cc3nccnc3cc2F)OC1(C)C.COC(=O)c1cc(OC)ccc1Nc1c(Br)c(C)nn1-c1ccccc1C>>COC(=O)c1cc(OC)ccc1Nc1c(-c2cc3nccnc3cc2F)c(C)nn1-c1ccccc1C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,O=C([O-])[O-].[Na+].[Na+],test
US20080255083A1,O=C(N1CCc2ccc(C(O)Cn3ccc(OCc4ccccc4)cc3=O)cc2CC1)C(F)(F)F>>O=c1cc(OCc2ccccc2)ccn1CC(O)c1ccc2c(c1)CCNCC2,,CO,,[Na+].[OH-],,test
US20140336190A1,Cc1cccc([Mg]Br)n1.Cc1noc(C)c1-c1cc(C(=O)C2OCCO2)c2nc(C3CC3)n(C(=O)OC(C)(C)C)c2c1>>Cc1ncccc1C(O)(c1cc(-c2c(C)noc2C)cc2c1nc(C1CC1)n2C(=O)OC(C)(C)C)C1OCCO1,,C1CCOC1,,,,test
US20090240045A1,CC(C)(C)O[C@@H]1C[C@@H](CO)N(C(=O)OCc2ccccc2)C1.O=C1NC(=O)c2ccccc21>>CC(C)(C)O[C@@H]1C[C@@H](CN2C(=O)c3ccccc3C2=O)N(C(=O)OCc2ccccc2)C1,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070155839A1,CC1(C)CC(=C(c2ccc(O)cc2)c2ccc(Br)cc2)CC(C)(C)C1.COC(=O)c1ccccc1B(O)O>>COC(=O)c1ccccc1-c1ccc(C(=C2CC(C)(C)CC(C)(C)C2)c2ccc(O)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US05077297,BrBr.O=c1cc(C(F)(F)F)ncn1-c1c(F)cc(C(F)(F)F)cc1F>>O=c1c(Br)c(C(F)(F)F)ncn1-c1c(F)cc(C(F)(F)F)cc1F,,CC(=O)O,,CC(=O)[O-].[Na+],,test
US05246948,CC(C)(C)c1ccc(C(=O)Cl)cc1.Cl.NCCCSc1ccncc1>>CC(C)(C)c1ccc(C(=O)NCCCSc2ccncc2)cc1.Cl,,ClCCl,,CCN(CC)CC,Cl,test
US20040259923A1,BrC(Br)(Br)Br.CC(=O)Nc1nc(CCc2ccc(CO)cc2)cs1>>CC(=O)Nc1nc(CCc2ccc(CBr)cc2)cs1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20060142576A1,CC#N.O=C(Cl)c1ccc(Cl)cc1Cl>>N#CCC(=O)c1ccc(Cl)cc1Cl,,C1CCOC1,,[Li]CCCC,,test
US03987027,N#CC(Cl)Cc1ccc(C(=O)O)cc1>>N#CC=Cc1ccc(C(=O)O)cc1,,CO,,[K+].[OH-],,test
US20130072519A1,CC(C)Oc1ccc(-c2ccccc2C(=O)O)cc1.CCOC(=O)C(C(=O)OCC)c1ccc(N)c(C(=O)N(C)C)c1>>CCOC(=O)C(C(=O)OCC)c1ccc(NC(=O)c2ccccc2-c2ccc(OC(C)C)cc2)c(C(=O)N(C)C)c1,CN(C)C=O,CC1CCCO1,,CCN(C(C)C)C(C)C,O=C(Cl)C(=O)Cl,test
US20140148433A1,COc1ccc(CNc2nc(-c3nn(Cc4ccccc4F)c4ncc(F)cc34)ncc2N)c(OC)c1.NS(N)(=O)=O>>COc1ccc(CN2c3nc(-c4nn(Cc5ccccc5F)c5ncc(F)cc45)ncc3NS2(=O)=O)c(OC)c1,,ClCCl,,c1ccncc1,,test
US20160007600A1,CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1N.Cc1ccc(C=CC(=O)O)cc1>>CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(=O)/C=C/c1ccc(C)cc1,CN(C)c1ccncc1,C1CCOC1,CN(C)C=O,CCN=C=NCCCN(C)C,Cl,test
US04636521,CC(CN1C(=O)c2ccccc2C1=O)c1c[nH]c2ccc(CN)cc12.CS(=O)(=O)Cl>>CC(CN1C(=O)c2ccccc2C1=O)c1c[nH]c2ccc(CNS(C)(=O)=O)cc12,,c1ccncc1,,,,test
US20020049345A1,CC(C)(C=O)CO.CCOC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1>>CCOC(=O)/C=C/C(C)(C)CO,,ClCCl,,,,test
US20150141455A1,COCC(=O)N[C@@H]1C[C@H]1c1ccccc1Cl>>N[C@@H]1C[C@H]1c1ccccc1Cl,,Cl,,,,test
US20130045998A1,CN(C)C=O.O=C(O)c1cn(Cc2c(F)cccc2F)nn1>>NC(=O)c1cn(Cc2c(F)cccc2F)nn1,,C1CCOC1,,O=C(Cl)C(=O)Cl,,test
US20070259854A1,NN.O=C(Cl)C1(c2cccs2)CCOCC1>>NNC(=O)C1(c2cccs2)CCOCC1,,C1CCOC1,,O,,test
US05250548,CCCCN.N#Cc1cccnc1Cl>>CCCCNc1ncccc1C#N,,CC(C)O,,,,test
US20050176645A1,COc1ccc2c3c1O[C@H]1C(=O)CC[C@H]4[C@@H](C2)N(C)CC[C@]314.C[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC[C@H]1C(=O)O>>COc1ccc2c3c1O[C@H]1C(=O)CC[C@H]4[C@@H](C2)N(C)CC[C@]314.C[C@H](N)C(=O)N1CCC[C@H]1C(=O)O,,C1COCCO1,,Cl,,test
US04621125,CC#N.CCN(CC)S(F)(F)F.CCN(CC)[Si](C)(C)C.O=C(F)F>>CCN(CC)[S+](N(CC)CC)N(CC)CC.[O-]C(F)(F)F,,CC#N,,,,test
US20160176891A1,C#CCC(C(=O)OCC)C(=O)OCC.CC(=N)N>>C#CCc1c(O)nc(C)[nH]c1=O,,CO,,Cl,[Na],test
US20130116245A1,CC(C)(C)N.O=C(O)c1cc2c(s1)CCCC2>>CC(C)(C)NC(=O)c1cc2c(s1)CCCC2,,ClCCl,,O=S(Cl)Cl,,test
US20100197655A1,Cn1nccc1-c1cc(OC(F)(F)F)ccc1OCc1ccccc1>>Cn1nccc1-c1cc(OC(F)(F)F)ccc1O,[Pd],CO,,,,test
US04564619,CC(=O)CC(=O)OCCN(C(=O)CCCOc1ccc2[nH]c(=O)ccc2c1)C1CCCCC1.O=Cc1cccc([N+](=O)[O-])c1>>CC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(=O)OCCN(C(=O)CCCOc1ccc2[nH]c(=O)ccc2c1)C1CCCCC1,,c1ccncc1,,,,test
US20100081680A1,BrBr.O=S(=O)(c1ccc(C(F)(F)F)cc1)n1cccc1>>O=S(=O)(c1ccc(C(F)(F)F)cc1)n1ccc(Br)c1,,CC(=O)O,ClCCl,[Na+].[OH-],,test
US20100305099A1,CN(c1ncccc1CN)S(C)(=O)=O.Clc1ncc(Cl)c(Cl)n1>>CN(c1ncccc1CNc1nc(Cl)ncc1Cl)S(C)(=O)=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US06358974B1,CC(C)(C)OC(=O)N1Cc2cc(Br)ccc2C(C)(C)C1.N#C[Cu]>>CC1(C)CNCc2cc(C#N)ccc21,,CN1CCCC1=O,,N,O,test
US20120270863A1,COc1cc2c(cc1OC)CCC(C(=O)O)=C2.O=S(Cl)Cl>>COc1cc2c(cc1OC)CCC(C(=O)Cl)=C2,,Cc1ccccc1,,,,test
US20160031871A1,CC(=O)Cl.Nc1ncc(CN2CCC(c3ccccc3)CC2)s1>>CC(=O)Nc1ncc(CN2CCC(c3ccccc3)CC2)s1,,ClCCl,,Cl,c1ccncc1,test
US04739066,CCOC(=O)C(=O)CCCCC1CCN(C(=O)OCc2ccccc2)CC1.N[C@H]1CSc2ccccc2NC1=O>>CCOC(=O)C(CCCCC1CCN(C(=O)OCc2ccccc2)CC1)N[C@H]1CSc2ccccc2NC1=O,,CCO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20100130545A1,O=C1CC2CCC1CC2(O)c1nccs1>>O=C1CC2CCC1C=C2c1nccs1,,C1CCOC1,,,,test
US20050137403A1,S=P(c1ccccc1)(c1ccccc1)c1ccccc1[C@@H]1COC(C23CC4CC(CC(C4)C2)C3)=N1>>CC(C)(C)C1=N[C@H](c2ccccc2P(=S)(C2CCCCC2)C2CCCCC2)CO1,,ClC(Cl)Cl,,,,test
US05789440,CNCc1ccccc1.O=C1CCC=C(c2ccccc2)O1>>CN(Cc1ccccc1)C(=O)CCCC(=O)c1ccccc1,,Cc1ccccc1,,CCOC(C)=O,Cl,test
US20080280961A1,CN(CCCN)Cc1ccc(Cl)c(Cl)c1.O=C(Br)CBr>>Br.CN(CCCNC(=O)CBr)Cc1ccc(Cl)c(Cl)c1,,ClCCl,,,,test
US20150094467A1,NCc1ccc(Br)cc1N.O=C(n1ccnc1)n1ccnc1>>O=C1NCc2ccc(Br)cc2N1,,C1CCOC1,,,,test
US20150299121A1,C[C@H]1CNCCN1C(=O)C1CCCC1.O=Cc1cccc([N+](=O)[O-])c1Cl>>C[C@H]1CN(Cc2cccc([N+](=O)[O-])c2Cl)CCN1C(=O)C1CCCC1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20120208817A1,COC(=O)c1c(O)cc(C=O)cc1Cl.NC(N)=O.O=C(Cc1ccccc1)c1ccccc1>>O=C1NC(c2ccccc2)=C(c2ccccc2)C(c2cc(O)c(C(=O)O)c(Cl)c2)N1,,CCO,,Cl,,test
US20160002204A1,Nc1cc[nH]c(=O)c1.O=C(Cl)Cc1ccccc1>>O=C(Cc1ccccc1)Nc1cc[nH]c(=O)c1,,CN(C)C=O,O,c1ccncc1,,test
US20160272596A1,CC(C)(C)OC(=O)N[C@H]1CNc2ccccc2N(Cc2cccc3ccccc23)C1=O.CI>>CN1C[C@H](NC(=O)OC(C)(C)C)C(=O)N(Cc2cccc3ccccc23)c2ccccc21,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US04594343,N#CC(c1ccccc1)(c1ccccc1)C1CCN(Cc2ccccc2)C1.O=C(Cl)Oc1ccccc1>>N#CC(c1ccccc1)(c1ccccc1)C1CCN(C(=O)Oc2ccccc2)C1,,ClCCl,,c1ccncc1,,test
US20140018319A1,CCNc1nc(Nc2cc(C#N)cc(N3CC[C@@H](N)[C@H](O)C3)c2Cl)nn2c(C#N)cnc12.COCCOCCOCCOCCOCCOCCOC(=O)Cl>>CCNc1nc(Nc2cc(C#N)cc(N3CC[C@@H](NC(=O)OCCOCCOCCOCCOCCOCCOC)[C@H](O)C3)c2Cl)nn2c(C#N)cnc12,,CO,,CCN(C(C)C)C(C)C,,test
US05491173,CN(C)CCOc1ccc(C(=C(CCCl)c2ccccc2)c2ccc(OCc3ccccc3)cc2)cc1>>CN(C)CCOc1ccc(/C(=C(/CCCl)c2ccccc2)c2ccc(O)cc2)cc1,CCN(CC)CC,CCO,CCOC(C)=O,,,test
US05489600,CC(C)(C)[Si](C)(C)OC1CCCNC1.CCCCCCCCCCCC(=O)O>>CCCCCCCCCCCC(=O)N1CCCC(O[Si](C)(C)C(C)(C)C)C1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20080095701A1,[N-]=[N+]=NCCOCCOCCOCCOCCOCCNC(=O)COCC(=O)O>>NCCOCCOCCOCCOCCOCCNC(=O)COCC(=O)O,,O,,,,test
US20130072492A1,CC1(C(=O)NN)C(=O)Nc2nc(-c3nn(CCC(F)(F)C(F)(F)F)c4ncccc34)nc(N)c21.O=CO>>CC1(C(=O)NNC=O)C(=O)Nc2nc(-c3nn(CCC(F)(F)C(F)(F)F)c4ncccc34)nc(N)c21,,CC#N,,,,test
US20080051416A1,CC(C)(C)CNC(=O)c1ccc(Br)c(NC(=O)OCc2ccccc2)c1.Cc1c(F)cc(C(=O)NC2CC2)cc1B1OC(C)(C)C(C)(C)O1>>Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC(C)(C)C)cc1N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20130066055A1,CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)CCCC(=O)O)C(C)C.NNC(=O)CCCCCN1C(=O)C=CC1=O>>CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)CCCC(=O)NNC(=O)CCCCCN1C(=O)C=CC1=O)C(C)C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090227566A1,CC(C)(C)OO.CSc1ccc(C(=O)Nc2ccccc2C(=O)Nc2ccc(Cl)cn2)c(OC2CCN(C(=O)OC(C)(C)C)CC2)c1>>CS(=O)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2ccc(Cl)cn2)c(OC2CCN(C(=O)OC(C)(C)C)CC2)c1,,ClC(Cl)Cl,,CC1(C)C2CCC1(CS(=O)(=O)O)C(=O)C2,,test
US20110053905A1,COC(=O)c1cc(-c2cc(Oc3ccc(N)cc3)ccn2)cs1.Cc1ccc(F)c(N=C=O)c1>>COC(=O)c1cc(-c2cc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)ccn2)cs1,,C1CCOC1,,O,,test
US20040077696A1,CN1CCNCC1.O=C(NC1CC1)c1cc(NCc2cnc(Nc3cccc(Br)n3)s2)c(F)cc1F>>CN1CCN(c2cccc(Nc3ncc(CNc4cc(C(=O)NC5CC5)c(F)cc4F)s3)n2)CC1,,ClCCl,,,,test
US20130131042A1,CN(C)C=O.O=C1CC(c2cc(F)c(F)cc2F)=NN1c1ccccc1.O=P(Cl)(Cl)Cl>>O=Cc1c(-c2cc(F)c(F)cc2F)nn(-c2ccccc2)c1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20150094330A1,Brc1cccc2c1CNC2.COc1cccc(CBr)c1>>COc1cccc(CN2Cc3cccc(Br)c3C2)c1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US05840732,CC(C)(CCO)CCSc1cccc2nccn12.CS(=O)(=O)Cl>>CC(C)(CCOS(C)(=O)=O)CCSc1cccc2nccn12,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20100130495A1,CC(C(=O)Cl)c1ccccc1.CC(C)(C)OC(=O)N1CCC(=O)CC1>>CC(C(=O)C1CN(C(=O)OC(C)(C)C)CCC1=O)c1ccccc1,,C1CCOC1,Cc1ccccc1,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US08304419B2,N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CN)c2F)c1.O=C(O)c1nc[nH]n1>>N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CNC(=O)c3nc[nH]n3)c2F)c1,,CN(C)C=O,,ClCCCl,On1nnc2ccccc21,test
US20160264567A1,CC(C)Oc1nc(CN2C(=O)c3ccccc3C2=O)cc(-c2cnc(C(F)(F)F)nc2)n1>>CC(C)Oc1nc(CN)cc(-c2cnc(C(F)(F)F)nc2)n1,,CO,,NN,O,test
US20100160357A1,CC(=O)Oc1ccc2cc(C=O)c(Cl)nc2c1>>O=Cc1cnc2cc(O)ccc2c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,CCN(CC)CC,O,test
US20090306066A1,CN(C)C1CN(c2cc(Cl)cc(NNC(=O)[C@H](CC3CCCC3)CN(C=O)OCc3ccccc3)c2F)CC12CC2>>CN(C)C1CN(c2cc(Cl)cc(NNC(=O)[C@H](CC3CCCC3)CN(O)C=O)c2F)CC12CC2,[Rh],CO,,,,test
US06653321B1,COC(=O)c1cc(N)cc(C(=O)OC)c1.Cc1ccc(C(=O)Cl)cc1>>COC(=O)c1cc(NC(=O)c2ccc(C)cc2)cc(C(=O)OC)c1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,,test
US20030055084A1,CC(C)(C)[Si](C)(C)Cl.OC1CC[C@@H](c2cc3cc(C(F)(F)F)ccc3o2)O1>>CC(C)(C)[Si](C)(C)OC1CC[C@@H](c2cc3cc(C(F)(F)F)ccc3o2)O1,,CCOC(C)=O,ClCCl,c1c[nH]cn1,,test
US20080269277A1,NNC(=O)c1cc2cc(Cl)ncc2[nH]1.O=C=Nc1cccs1>>O=C(NNC(=O)c1cc2cc(Cl)ncc2[nH]1)Nc1cccs1,,C1COCCO1,Cc1ccccc1,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US06271403B1,C[C@]12C[C@@H](O)[C@@H]3[C@H]4CCC(=O)C=C4CC[C@H]3[C@@H]1CCC2=O.O=S(=O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>C[C@]12C[C@H](F)[C@@H]3[C@H]4CCC(=O)C=C4CC[C@H]3[C@@H]1CCC2=O,,CCOC(C)=O,Cc1ccccc1,C1CCC2=NCCCN2CC1,,test
US20130296377A1,Cc1ccc(S(=O)(=O)n2ccc3c(Cc4nc5cc(C#N)ccc5[nH]4)c(COCOCC[Si](C)(C)C)cc(C)c32)cc1>>Cc1ccc(S(=O)(=O)n2ccc3c(Cc4nc5cc(C#N)ccc5[nH]4)c(CO)cc(C)c32)cc1,,ClCCl,,CCOCC,FB(F)F,test
US20160168165A1,CCN=C=O.ClCCl.NCCCN1C(=O)S/C(=C\c2ccc(Sc3nc4ccccc4[nH]3)o2)C1=O>>CCNC(=O)NCCCN1C(=O)S/C(=C\c2ccc(Sc3nc4ccccc4n3C)o2)C1=O,,ClCCl,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20040044057A1,c1c[nH]cn1.c1ccc(C2CO2)cc1>>OC(Cc1ncc[nH]1)c1ccccc1,,CCO,,c1ccncc1,,test
US20100160303A1,[N-]=[N+]=NCc1ccc2c(c1)[nH]c1c(C(N)=O)ccc(Br)c12>>NCc1ccc2c(c1)[nH]c1c(C(N)=O)ccc(Br)c12,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070142446A1,CCNCC.COc1cccc2c(-c3csc(CCl)n3)cn(CC3CCCCC3)c12>>CCN(CC)Cc1nc(-c2cn(CC3CCCCC3)c3c(OC)cccc23)cs1.Cl,,CC#N,,,,test
US20070244125A1,C1CN[C@H](CN2CCCC2)C1.CCOC(=O)c1cc2cc(C(=O)O)ccc2[nH]1>>CCOC(=O)c1cc2cc(C(=O)N3CCC[C@H]3CN3CCCC3)ccc2[nH]1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20110105486A1,Br[Mg]C1CCCC1.CON(C)C(=O)c1sc(NC(=O)c2ccncc2)nc1-c1ccco1>>O=C(Nc1nc(-c2ccco2)c(C(=O)C2CCCC2)s1)c1ccncc1,,C1CCOC1,,CCOCC,[Cl-].[NH4+],test
US06921740B1,C1CCOC1.CCN(CC)CC.Nc1ccccc1O.O=S(=O)(Cl)c1ccc(-c2ccc(S(=O)(=O)Cl)cc2)cc1>>O=S(=O)(Nc1ccccc1O)c1ccc(-c2ccc(S(=O)(=O)Nc3ccccc3O)cc2)cc1,,C1CCOC1,,,,test
US20140275129A1,CCOC(=O)N1C(=O)c2ccccc2C1=O.NCc1ccc(C(=O)O)cc1>>O=C(O)c1ccc(CN2C(=O)c3ccccc3C2=O)cc1,,O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20110269804A1,NO.O=CC1=NOC(c2cc(Cl)cc(Cl)c2)(C(F)(F)F)C1>>ON=CC1=NOC(c2cc(Cl)cc(Cl)c2)(C(F)(F)F)C1,O,CCO,,,,test
US20160129013A1,CC(C)(C)OC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CCCCCN1C(=O)C=CC1=O>>O=C(O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CCCCCN1C(=O)C=CC1=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080119518A1,COc1ccc(C(C)=O)cc1CCN1CCC(n2ccc3ccc(C(N)=O)cc32)CC1>>COc1ccc(C(C)O)cc1CCN1CCC(n2ccc3ccc(C(N)=O)cc32)CC1,,CO,,[BH4-].[Na+],,test
US06184207B2,CC(C)(C)OC(=O)NC1CCCNC1=O.CCOC(=O)CBr>>CCOC(=O)CN1CCCC(NC(=O)OC(C)(C)C)C1=O,,CN(C)C=O,,[H-].[Na+],,test
US20040138206A1,CCOC(=O)CBr.COC(=O)C(CO)NS(=O)(=O)c1ccc(OC)cc1>>CCOC(=O)CN(C(CO)C(=O)OC)S(=O)(=O)c1ccc(OC)cc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05631403,CC(C)N(C(=O)CCl)c1ccc(F)cc1.O>>CC(C)N(C(=O)CO)c1ccc(F)cc1,,CN1CCCC1=O,,O=C([O-])[O-].[Na+].[Na+],,test
US05484911,CC(C)(C)[Si](C)(C)Cl.CCCCCCCCCCCCCCOCC(O)CO>>CCCCCCCCCCCCCCOCC(O)CO[Si](C)(C)C(C)(C)C,,CN(C)C=O,,c1c[nH]cn1,,test
US04810708,BrCc1ccccc1.O=c1c2c(n(-c3cccc(Cl)c3)c3ncccc13)CCNC2>>O=c1c2c(n(-c3cccc(Cl)c3)c3ncccc13)CCN(Cc1ccccc1)C2,,CC(C)=O,,,,test
US20110301176A1,CCOC(=O)C(Cl)C(=O)C(C)C.C[C@@]1(c2ccc(Cl)nc2)NC(=S)N[C@@H]1c1ccc(Cl)c(F)c1>>CCOC(=O)C1=C(C(C)C)N2C(=N[C@@](C)(c3ccc(Cl)nc3)[C@H]2c2ccc(Cl)c(F)c2)S1,,CCOC(C)=O,,CCO,,test
US04341787,Cc1nc[nH]c1CSCCN.O=C1NC(=S)CS1>>Cc1nc[nH]c1CSCCNC1=NC(=O)SC1,,CO,,,,test
US20160083391A1,CC(=O)NCc1nc2c(C3CCCC3)n[nH]c2c(=O)[nH]1>>NCc1nc2c(C3CCCC3)n[nH]c2c(=O)[nH]1,,CO,Cl,,,test
US20080194561A1,CN(C)/C=C/C(=O)c1ccc(C(=O)NCC(C)(C)CN(C)C)s1.COc1ccc(NC(=N)N)cc1>>COc1ccc(Nc2nccc(-c3ccc(C(=O)NCC(C)(C)CN(C)C)s3)n2)cc1,,CCO,,Cl,[Na],test
US06956047B1,Cc1cc(Cl)c(C)c(Cl)n1.O=C(OO)c1cccc(Cl)c1>>Cc1c(Cl)cc(C)[n+]([O-])c1Cl,,ClC(Cl)Cl,,,,test
US20070254931A1,O=[N+]([O-])c1cccc(CBr)c1[N+](=O)[O-].c1ccc(P(c2ccccc2)c2ccccc2)cc1>>O=[N+]([O-])c1cccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c1[N+](=O)[O-].[Br-],,CC(C)=O,,,,test
US20120316147A1,CC(C)CC(=O)c1cccnn1.[NH4+]>>CC(C)CC(N)c1cccnn1,,CO,,[BH3-]C#N.[Na+],,test
US20110086834A1,CC(=O)c1nc(Br)cs1.CO.COC(OC)OC>>COC(C)(OC)c1nc(Br)cs1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,O=C([O-])O.[Na+],test
US08022092B2,COC(=O)C(C(C)C)N1C(=O)NC(COc2ccc(Br)cc2)C1=O>>CC(C)C(C(=O)O)N1C(=O)NC(COc2ccc(Br)cc2)C1=O,,Cl,,,,test
US20140051679A1,BrC1CC1.Cc1ccccc1C#N>>Cc1ccccc1C(N)C1CC1,,CO,,C1CCOC1,[BH4-].[Na+],test
US20120022109A1,CN(CC(=O)OC(C)(C)C)Cc1c(F)cc(C#N)cc1F.NO>>CN(CC(=O)OC(C)(C)C)Cc1c(F)cc(C(N)=NO)cc1F,,CCO,,,,test
US20040171620A1,[N-]=[N+]=N[C@H]1CC[C@H](C(N)=O)C[C@@H]1O>>NC(=O)[C@H]1CC[C@H](N)[C@@H](O)C1,[Pd],CO,,,,test
US04240820,CC(C)(C)c1csc(N=C=O)c1C#N.CNC>>CN(C)C(=O)Nc1scc(C(C)(C)C)c1C#N,,Cc1ccccc1,,,,test
US04699899,CCCCCCCCCCCCCCCCCCNC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O.CCCCCCCCCCCCN=C=O>>CCCCCCCCCCCCCCCCCCN(C(=O)NCCCCCCCCCCCC)C1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O,,C1CCOC1,CCO,,,test
US20030078259A1,BrCc1ccccc1.N=C1SCCN1Cc1ccc(Cl)nc1>>Clc1ccc(CN2CCSC2=NCc2ccccc2)cn1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20070066657A1,CC(C)(C)[Si](C)(C)OC1CC(=O)OC(=O)C1.N>>CC(C)(C)[Si](C)(C)OC1CC(=O)NC(=O)C1,,C1COCCO1,,[NH4+].[OH-],,test
US20080085909A1,CC(C)(C)OC(=O)N1CC[C@@H](CN)C1.O=[N+]([O-])c1ccc(Cl)nc1NCc1c(Cl)cccc1Cl>>CC(C)(C)OC(=O)N1CC[C@@H](CNc2ccc([N+](=O)[O-])c(NCc3c(Cl)cccc3Cl)n2)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080081818A1,COC(=O)c1nc(N)sc1CO[Si](C)(C)C(C)(C)C>>COC(=O)c1nc(N)sc1CO,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110021511A1,CCO.Clc1nc(N2CCNCC2)c2[nH]c3cc(Br)ccc3c2n1>>CCOc1nc(N2CCNCC2)c2[nH]c3cc(Br)ccc3c2n1,,CCO,,C,C[O-].[Na+],test
US20030166639A1,CC(C)(C)OC(=O)Nc1cc(N2CCOCC2)c(C(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-c2cccnc2)c1>>O=C1CC(c2cccc(-c3cccnc3)c2)=Nc2cc(N3CCOCC3)c(C(F)(F)F)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070167406A1,COC(=O)CC(C)=O.Nc1cccc(C(F)(F)F)c1>>COC(=O)C=C(C)Nc1cccc(C(F)(F)F)c1,,c1ccccc1,,CC(=O)O,,test
US20100249229A1,C=CCCC(=O)C(C)C(=O)OCC>>C=CCCC(O)C(C)C(=O)OCC,,CO,,[BH4-].[Na+],,test
US20160122336A1,CC(C)(O)CN.O=C(O)c1nc(Br)cs1>>CC(C)(O)CNC(=O)c1nc(Br)cs1,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20160257682A1,CC(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F.Clc1cc2[nH]nc(I)c2cn1>>CC(n1nc(I)c2cnc(Cl)cc21)C(F)(F)F,,CN(C)C=O,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040023995A1,CC(=O)O[C@H](C)CCCCn1c(=O)c2c(OS(=O)(=O)C(F)(F)F)cc(C)nc2n(C)c1=O.CNC>>CC(=O)O[C@H](C)CCCCn1c(=O)c2c(N(C)C)cc(C)nc2n(C)c1=O,,C1CCOC1,,,,test
US20100273805A1,CCOC(=O)/C(N)=N\O.Cc1cccc(C(=O)Cl)c1>>CCOC(=O)/C(N)=N\OC(=O)c1cccc(C)c1,,COC(C)(C)C,,ClCCl,,test
US20060235222A1,C1CCOC1.CC[Mg]Br.COC(=O)c1ccc2nc(C)[nH]c2c1>>CCC(O)(CC)c1ccc2nc(C)[nH]c2c1,,O,,,,test
US20100056527A1,Cc1cc(NC(=O)OCC[Si](C)(C)C)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12>>Cc1cc(N)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12,,C1CCOC1,CCOC(C)=O,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05217999,N#CCC#N.O=Cc1ccc(O)c(O)c1>>N#CC(C#N)=Cc1ccc(O)c(O)c1,C1CCNCC1,CCO,,O,,test
US20090136473A1,COc1ccc(Cc2ccc(F)nc2)c(F)c1-c1cccc(Cl)c1.O=C(O)[C@@H]1CCCN1>>COc1ccc(Cc2ccc(N3CCC[C@@H]3C(=O)O)nc2)c(F)c1-c1cccc(Cl)c1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20160068515A1,CCc1cnc(N2CCN(c3ncc(-c4ccc(-n5cnn(CCNC(=O)OC(C)(C)C)c5=O)c(F)c4)cc3C#N)[C@@H](C)C2)nc1.Cl>>CCc1cnc(N2CCN(c3ncc(-c4ccc(-n5cnn(CCN)c5=O)c(F)c4)cc3C#N)[C@@H](C)C2)nc1.Cl,,CCOC(C)=O,,,,test
US20050272764A1,Cc1cc([N+](=O)[O-])c(N)nc1Cl.OCC(F)F>>Cc1cc([N+](=O)[O-])c(N)nc1OCC(F)F,,C1CCOC1,,O,[H-].[Na+],test
US20110009454A1,COc1cccc(O)c1.N#Cc1cccc(F)c1>>COc1cccc(Oc2cccc(C#N)c2)c1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20100324068A1,COC(=O)C(C)(C)NC(=O)Cc1ccc(-c2ccc(-c3nc(C(N)=O)c(C)nc3C)cc2)c(Cl)c1>>Cc1nc(C)c(-c2ccc(-c3ccc(CC(=O)NC(C)(C)C(=O)O)cc3Cl)cc2)nc1C(N)=O,,CC(C)(C)O,,[K+].[OH-],,test
US20140205537A1,CCOC(=O)Cc1cc(OC(C)C)ncc1[N+](=O)[O-]>>CC(C)Oc1cc2c(cn1)NC(=O)C2,[Fe],CC(=O)O,,,,test
US20040053163A1,CCCN.O=S(=O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>CCCNS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F,,CCOC(C)=O,,,,test
US20160096827A1,COc1cc(N)ccc1OC(F)F.N#Cc1cc(-c2ncnc(Cl)n2)ccc1OC1CCOCC1>>COc1cc(Nc2ncnc(-c3ccc(OC4CCOCC4)c(C#N)c3)n2)ccc1OC(F)F,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20040019016A1,BrCCCCBr.N#Cc1ccc(Nn2cnnc2)cc1>>N#Cc1ccc(N(CCCCBr)n2cnnc2)cc1,,CS(C)=O,,CCOC(C)=O,[H-].[Na+],test
US20040048908A1,CCOC(=O)c1cnoc1-c1ccc(OC)cc1>>COc1ccc(-c2oncc2CO)cc1,,C1CCOC1,,Cl,CC(C)C[Al+]CC(C)C.[H-],test
US20130267532A1,CC(C)(C)[Si](C)(C)Cl.CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(Br)cc1OC>>CCC[C@@H](CCO[Si](C)(C)C(C)(C)C)Nc1nc(N)nc(C)c1Cc1ccc(Br)cc1OC,,CN(C)C=O,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20110003787A1,COC[C@H](C)Oc1cc(O[Si](C(C)C)(C(C)C)C(C)C)cc(-c2ccc(C(=O)O)[nH]2)c1.NC[C@H](O)CO>>COC[C@H](C)Oc1cc(O[Si](C(C)C)(C(C)C)C(C)C)cc(-c2ccc(C(=O)NC[C@H](O)CO)[nH]2)c1,,CO,,COc1nc(OC)nc([N+]2(C)CCOCC2)n1.[Cl-],,test
US05648382,CC=C(C)[C@@]1(O)[C@H](Br)[C@H](OC(=O)NC(=O)CCl)CC[C@]12CO2.O=C(OO)c1cccc(Cl)c1>>CC1OC1(C)[C@@]1(O)[C@H](Br)[C@H](OC(=O)NC(=O)CCl)CC[C@]12CO2,,ClCCl,,,,test
US20120101095A1,CCCC[Sn](CCCC)(CCCC)c1cccc(C)n1.CCOC(=O)c1sc2nc(SC)nc(Cl)c2c1N>>CCOC(=O)c1sc2nc(SC)nc(-c3cccc(C)n3)c2c1N,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,,,,test
US20140336388A1,CCn1nc(C2CCN(c3ccc(N)cc3)CC2)oc1=O.O=C(O)c1ccc([N+](=O)[O-])o1.Oc1cccc2[nH]nnc12>>CCn1nc(C2CCN(c3ccc(-c4cc([N+](=O)[O-])oc4C(N)=O)cc3)CC2)oc1=O.N#N,,CN(C)C=O,,CCN=C=NCCCN(C)C,,test
US20090069300A1,C=CCN1CCc2cc(Br)ccc2C1=O.O=[Os](=O)(=O)=O>>O=CCN1CCc2cc(Br)ccc2C1=O,O=[Os](=O)(=O)=O,C1CCOC1,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20120142717A1,N#C/C=C/c1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cc1>>N#CCCc1ccc(Oc2ccc(Cl)c(C(F)(F)F)c2)cc1,[Pd],C1CCOC1,,,,test
US20090143352A1,C1COCCN1.COc1ccccc1-c1cn(S(=O)(=O)c2ccc(C)cc2)c2ncc(-c3ccc(N=C=O)c(C(=O)N(C)C)c3)cc12>>COc1ccccc1-c1c[nH]c2ncc(-c3ccc(NC(=O)N4CCOCC4)c(C(=O)N(C)C)c3)cc12,,ClCCl,,,,test
US04868177,CCCCCC(=O)Cl.Nc1c2c(nc3ccccc13)CCCC2N>>CCCCCC(=O)NC1CCCc2nc3ccccc3c(N)c21,,C1CCOC1,,CCN(CC)CC,,test
US20050131052A1,C1COCCN1.CN(C(=O)CCl)[C@@H]1c2ccccc2C[C@H]1NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1>>CN(C(=O)CN1CCOCC1)[C@H]1c2ccccc2C[C@@H]1NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1,,ClCCl,,,,test
US20040014751A1,CCOC(=O)CS.Cc1cc2c(c(Cl)n1)c(=O)cc(Nc1ccccc1)n2-c1ccccc1>>CCOC(=O)CSc1nc(C)cc2c1c(=O)cc(Nc1ccccc1)n2-c1ccccc1,,CCO,,,,test
US20160068512A1,Clc1ccc(C(c2ccc(Cl)cc2)c2ccc3ncnc(Cl)c3c2)cc1.O=S(=O)(NC1CCNC1)C(F)(F)F>>O=S(=O)(NC1CCN(c2ncnc3ccc(C(c4ccc(Cl)cc4)c4ccc(Cl)cc4)cc23)C1)C(F)(F)F,,CC(C)O,,Cl,,test
US04684661,CC(C)(C)C#CCCO.CNCc1cccc2ccccc12>>CN(CCC#CC(C)(C)C)Cc1cccc2ccccc12,,CN(C)C=O,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20140349987A1,NO.Nc1ccc(Br)cc1C(F)(F)F.OC(O)C(Cl)(Cl)Cl>>O=C(C=NO)Nc1ccc(Br)cc1C(F)(F)F,,Cl,O,O=S(=O)([O-])[O-].[Na+].[Na+],,test
US04619917,CCCCCCCCCCCCCCCCCCOCCC1(COCc2ccccc2)CCC(=O)O1>>CCCCCCCCCCCCCCCCCCOCCC1(CO)CCC(=O)O1,[Pd],O,,CCO,[H][H],test
US20060276433A1,CN(Cc1csc(C=O)n1)C(=O)OC(C)(C)C.NNc1ccc(-c2cnco2)cc1>>CN(Cc1csc(C=NNc2ccc(-c3cnco3)cc2)n1)C(=O)OC(C)(C)C,,CCO,,,,test
US20090023781A1,CC(C)(C)C[C@H](N=CC(F)(F)c1ccccn1)C12OCC(C)(CO1)CO2.Fc1ccc(Br)cc1>>CC(C)(C)C[C@H](N[C@@H](c1ccc(F)cc1)C(F)(F)c1ccccn1)C12OCC(C)(CO1)CO2,,CCOCC,,O,[Li]CCCC,test
US20090023747A1,CO.COC(OC)OC.O=C1CO[C@@H]2[C@@H](F)CN(C(=O)OCc3ccccc3)[C@H]12>>COC1(OC)CO[C@@H]2[C@@H](F)CN(C(=O)OCc3ccccc3)[C@@H]21,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20130109789A1,CI.COCC(CO)(COC1CCCCC1)C(C)C>>COCC(COC)(COC1CCCCC1)C(C)C,,C1CCOC1,,[H-].[Na+],,test
US20060094767A1,COCOCCC(O)Cn1cc([N+](=O)[O-])nc1Cl>>COCOCCC1Cn2cc([N+](=O)[O-])nc2O1,,C1COCCO1,,[H-].[Na+],,test
US20070197558A1,Nc1ccc(S)cc1.O=[N+]([O-])c1cc(OCc2ccccc2)ccc1Cl>>Nc1ccc(Sc2ccc(OCc3ccccc3)cc2[N+](=O)[O-])cc1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20040082542A1,CC(C)(C)c1ccc(Oc2cccc(C=O)c2)cc1.CCCCNc1cc(OCCCN(CC)CC)cc(OCCCN(CC)CC)c1N>>CCCCn1c(-c2cccc(Oc3ccc(C(C)(C)C)cc3)c2)nc2c(OCCCN(CC)CC)cc(OCCCN(CC)CC)cc21,,CCO,,,,test
US20060229349A1,CCN1C(=O)Cc2cc(NC[C@@H](O)CNC(=O)OC(C)(C)C)cc(F)c21.O=C(Cl)Cl>>CCN1C(=O)Cc2cc(N3C[C@H](CNC(=O)OC(C)(C)C)OC3=O)cc(F)c21,,ClCCl,,CCN(CC)CC,,test
US20130225548A1,CC(C)(C)OC(=O)N1CCN(c2ccc(-c3cc(C4CC4)cc(Nc4cc(C#N)ccn4)n3)cn2)CC1>>N#Cc1ccnc(Nc2cc(C3CC3)cc(-c3ccc(N4CCNCC4)nc3)n2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080009492A1,Cc1cc(C(=O)O)ccn1.Nc1cc(Br)cnc1N>>Cc1cc(-c2nc3cc(Br)cnc3[nH]2)ccn1,,O,,,,test
US20090270434A1,NC(=O)c1cnc(N2CCC(Oc3cc(F)ccc3Br)CC2)cn1>>N#Cc1cnc(N2CCC(Oc3cc(F)ccc3Br)CC2)cn1,,C1CCOC1,,CCN(CC)CC,O=C(OC(=O)C(F)(F)F)C(F)(F)F,test
US20090069288A1,CCOC(=O)/C(Cl)=N/Nc1ccccc1.N>>CCOC(=O)/C(N)=N/Nc1ccccc1,,C1COCCO1,,,,test
US20130096133A1,C1CNCCN1.COc1cc(CCl)cc(OC)c1OC>>COc1cc(CN2CCNCC2)cc(OC)c1OC,,C1CCOC1,,,,test
US20070238718A1,CC(=O)Nc1nc2c(s1)-c1c(c(C3CC3)nn1C1CCNCC1)CC2.CC(C)N1CCNCC1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(=O)Nc1nc2c(s1)-c1c(c(C3CC3)nn1C1CCN(C(=O)N3CCN(C(C)C)CC3)CC1)CC2,,C1CCOC1,ClCCl,CCN(CC)CC,,test
US20150175599A1,COc1cc(NC(=O)C(=O)c2c(C)n(Cc3ccc(Cl)cc3)c3ccc(CO)cc23)ccn1>>COc1cc(NC(=O)C(=O)c2c(C)n(Cc3ccc(Cl)cc3)c3ccc(C=O)cc23)ccn1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US04939133,CC(C)(C)c1cccc2c1OC(=O)C2=O.COc1ccc(CCc2ccc(N)cc2)cc1OC>>COc1ccc(CCc2ccc(NC(=O)C(=O)c3cccc(C(C)(C)C)c3O)cc2)cc1OC,,ClCCl,,,,test
US20110086834A1,Clc1nccc(-n2ccc3ccc(Br)cc32)n1.Nc1ccccc1>>Brc1ccc2ccn(-c3ccnc(Nc4ccccc4)n3)c2c1,,CCCCCO,,O=C(O)C(F)(F)F,,test
US06358980B1,CC#CCOc1ccc(S(=O)(=O)C2(C(=O)OC)CCN(C(=O)c3cccnc3)CC2)cc1>>CC#CCOc1ccc(S(=O)(=O)C2(C(=O)O)CCN(C(=O)c3cccnc3)CC2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20120122900A1,CC(=O)Cc1cccc(Cl)c1.COC(=O)[C@@H](CI)NC(=O)OC(C)(C)C>>COC(=O)C(CC(C(C)=O)c1cccc(Cl)c1)NC(=O)OC(C)(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100278833A1,COC(=O)c1sc(-n2cnc3cnccc32)cc1O.Fc1ccc(CBr)c(C(F)(F)F)c1>>COC(=O)c1sc(-n2cnc3cnccc32)cc1OCc1ccc(F)cc1C(F)(F)F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US06436964B1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CCCC[SnH](CCCC)CCCC>>CCCC[Sn](CCCC)(CCCC)C1(O)CCN(C(=O)OC(C)(C)C)CC1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US04260803,Cc1cc(Cl)cc(Cl)c1O.O=C(Cl)c1ccc(CCl)cc1>>Cc1cc(Cl)cc(Cl)c1OC(=O)c1ccc(CCl)cc1,,c1ccncc1,,Cc1ccccc1C,,test
US20080293775A1,CC(=O)Cl.CS(=O)(=O)c1ccc(Oc2cc(Cl)ccc2CS(N)(=O)=O)c(Cl)c1>>CC(=O)NS(=O)(=O)Cc1ccc(Cl)cc1Oc1ccc(S(C)(=O)=O)cc1Cl,,CC(=O)O,,,,test
US20130237525A1,COc1ccc([N+](=O)[O-])c(OC)c1C1CCCC(=O)N1Cc1ccc2ccccc2n1>>COc1ccc([N+](=O)[O-])c(O)c1C1CCCC(=O)N1Cc1ccc2ccccc2n1,,ClCCl,,O,,test
US20080032967A1,COC(=O)COc1ccc([N+](=O)[O-])c2ccccc12>>COC(=O)COc1ccc(N)c2ccccc12,[Pd],CO,,[H][H],,test
US20100152257A1,COC(=O)c1c(C)noc1-c1ccc(Br)cc1>>Cc1noc(-c2ccc(Br)cc2)c1C(=O)O,,CO,O,[Li+].[OH-],,test
US06211199B1,COc1ccc(C2(CCO)CCN(C(=O)c3cc(OC)c(OC)c(OC)c3)C2)cc1OC.CS(=O)(=O)Cl>>COc1ccc(C2(CCOS(C)(=O)=O)CCN(C(=O)c3cc(OC)c(OC)c(OC)c3)C2)cc1OC,,ClCCl,,CCN(CC)CC,,test
US05145865,C=C(CC(=O)O)C(=O)O.Cc1ccc(N)cc1>>Cc1ccc(N2CC(C(=O)O)CC2=O)cc1,,O,,,,test
US04622401,C=C(C)C#N.NNc1ccccn1>>CC1CN(c2ccccn2)N=C1N,,CCO,,[Na],,test
US20120101134A1,CC(C)Oc1ccc(-c2nnc(Br)s2)cc1C#N.CCOC(=O)CCCc1cccc(B2OC(C)(C)C(C)(C)O2)c1CC>>CCOC(=O)CCCc1cccc(-c2nnc(-c3ccc(OC(C)C)c(C#N)c3)s2)c1CC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US04558129,Cc1cccc(C)c1NC(=O)CN1CCNCC1.OC(CBr)C1COc2ccccc2O1>>Cc1cccc(C)c1NC(=O)CN1CCN(CC(O)C2COc3ccccc3O2)CC1,,CCO,,CCCCCC,,test
US05629406,CC(C)(C)OC(=O)N1CC[C@@H](O)[C@H]1COCc1ccccc1.O=C(O)c1ccccc1>>CC(C)(C)OC(=O)N1CC[C@H](OC(=O)c2ccccc2)[C@H]1COCc1ccccc1,,C1CCOC1,CCOC(C)=O,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090030040A1,C=O.CC(OCC1(c2ccccc2)CCNCC1)c1cc(C(F)(F)F)cc(-c2ccc(F)cc2)n1>>CC(OCC1(c2ccccc2)CCN(C)CC1)c1cc(C(F)(F)F)cc(-c2ccc(F)cc2)n1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20130109685A1,CCOC(=O)COc1ccc(Cl)cc1[C@@H]1c2ccccc2CCN1C(=O)OCc1ccccc1.NO>>O=C(COc1ccc(Cl)cc1[C@@H]1c2ccccc2CCN1C(=O)OCc1ccccc1)NO,,CC(C)O,,,,test
US20030212066A1,CI.Cc1ccc(S(=O)(=O)N2C(CO)CCC2c2ccc(F)cc2)cc1>>COCC1CCC(c2ccc(F)cc2)N1S(=O)(=O)c1ccc(C)cc1,,C1CCOC1,,[H-].[Na+],,test
US04296129,CCCCCCCCCCNC(=O)C=Cc1cccc(NC(=O)/C=C\C(=O)O)c1.CCN(CC)CCO>>CCCCCCCCCCNC(=O)C=Cc1cccc(NC(=O)/C=C\C(=O)OCCN(CC)CC)c1,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20080269220A1,C1CC2(CCS1)CO2.CCOC(=O)CCc1ccc(N(C2CCc3c(-c4c(C)cc(O)cc4C)cccc32)S(=O)(=O)c2ccccc2[N+](=O)[O-])cc1F>>CCOC(=O)CCc1ccc(N(C2CCc3c(-c4c(C)cc(OCC5(O)CCSCC5)cc4C)cccc32)S(=O)(=O)c2ccccc2[N+](=O)[O-])cc1F,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040023947A1,BrCc1ccccc1.CCOC(=O)C1=CNCCc2c1[nH]c1ccccc21>>CCOC(=O)C1=CN(Cc2ccccc2)CCc2c1[nH]c1ccccc21,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20140005213A1,C/C=C/C=O.Nc1cccc(C(=O)O)c1C1CC1>>Cc1ccc2ccc(C(=O)O)c(C3CC3)c2n1,,Cl,,ClCCl,[Na+].[OH-],test
US04387051,CC(=O)NCCSC1=C(C(=O)OCc2ccc([N+](=O)[O-])cc2)N2C(=O)[C@H]([C@H](C)O)[C@H]2C1.C[Si](C)(C)Cl>>CC(=O)NCCSC1=C(C(=O)OCc2ccc([N+](=O)[O-])cc2)N2C(=O)[C@H]([C@H](C)O[Si](C)(C)C)[C@H]2C1,,c1ccncc1,,,,test
US20090042852A1,COC(=O)C1(C)CCN(C(=O)OC(C)(C)C)CC1>>COC(=O)C1(C)CCNCC1,,C1CCOC1,,C1COCCO1,Cl,test
US20140031364A1,Cc1onc(-c2cccc(F)c2)c1C(=O)O.FC(F)(F)c1cccc(N2CCNCC2)c1>>Cc1onc(-c2cccc(F)c2)c1C(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US04625042,O=C(O)CCOc1ccc(F)cc1>>O=C1CCOc2ccc(F)cc21,,O=S(=O)(O)O,,,,test
US06063806,CC(=O)N1CC(CCC(=O)O)c2c(C)cc(C)cc21.CCO>>CCOC(=O)CCC1CN(C(C)=O)c2cc(C)cc(C)c21,,CCO,,Cl,,test
US20130079323A1,CCc1cc2c(O)nc(S)nc2[nH]1.CI>>CCc1cc2c(=O)[nH]c(SC)nc2[nH]1,,CCO,,[Na+].[OH-],,test
US04645765,CC(=O)Oc1cc(C=O)cc2c1C(COC(N)=O)C1(OC(C)=O)ON2CC2C1N2C(C)=O>>CC(=O)OC12ON(CC3C1N3C(C)=O)c1cc(C=O)cc(O)c1C2COC(N)=O,,CO,,CC(=O)O,O=C([O-])O.[Na+],test
US04772704,CCOC(=O)Nc1cnc(NCCCOc2cccc(CN3CCCCC3)c2)[nH]c1=O>>Nc1cnc(NCCCOc2cccc(CN3CCCCC3)c2)[nH]c1=O,,CC(=O)O,,[Na+].[OH-],,test
US20120270856A1,Cn1ccc(Nc2ncnc3ccc(O)cc23)n1.Fc1ncc(OCCC2OCCO2)cc1Cl>>Cn1ccc(Nc2ncnc3ccc(Oc4ncc(OCCC5OCCO5)cc4Cl)cc23)n1,,CC(=O)N(C)C,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US20150038528A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.N#CCc1ccc(F)cc1>>CC(C)(C)OC(=O)C(C#N)c1ccc(F)cc1,,C1CCCCC1,C1CCOC1,CC(C)[N-]C(C)C.[Li+],,test
US20120184574A1,C=CCBr.C[C@H](NS(=O)(=O)c1ccc(-c2cc3ccc(C4CC4)cc3n2C(=O)OC(C)(C)C)nc1)C(F)(F)F>>C=CCN([C@@H](C)C(F)(F)F)S(=O)(=O)c1ccc(-c2cc3ccc(C4CC4)cc3n2C(=O)OC(C)(C)C)nc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090186918A1,c1ccc(CNc2cnc3ccccc3n2)cc1>>Nc1cnc2ccccc2n1,[Pd],CO,,O=C[O-].[NH4+],,test
US20130225845A1,CCCCC(=O)Oc1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](OC(=O)CCCC)CC[C@@H]12>>CCCCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C,,O,,CO,[BH4-].[Na+],test
US20070196294A1,CC1CCC(C(C)C)C(OC(=O)CC(=O)OC2CC(C)CCC2C(C)C)C1.O=Cc1ccc([N+](=O)[O-])cc1>>CC1CCC(C(C)C)C(OC(=O)C(=Cc2ccc([N+](=O)[O-])cc2)C(=O)OC2CC(C)CCC2C(C)C)C1,,Cc1ccccc1,,O,,test
US20040014802A1,Nc1n[nH]c2cc(Cl)ccc12.O=C(Cl)C(F)(F)C(F)(F)C(F)(F)F>>O=C(Nc1n[nH]c2cc(Cl)ccc12)C(F)(F)C(F)(F)C(F)(F)F,,c1ccncc1,,,,test
US20080076924A1,Cc1ccccc1NC(=NC#N)N1CCNC(c2ccccc2)C1.O=C=Nc1ccc(Cl)cc1>>Cc1ccccc1NC(=NC#N)N1CCN(C(=O)Nc2ccc(Cl)cc2)C(c2ccccc2)C1,,C1CCOC1,CCOCC,O,,test
US20140206788A1,O.O=C(Cl)c1ccc2c(c1)C(=O)OC2=O.O=C1CCCCCO1>>O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1,,CC(C)=O,,c1ccncc1,,test
US20150119362A1,CCOC(=O)C(c1ccc(Nc2cc(CC)nc(-c3cccc(Cl)c3)n2)cc1)C(F)(F)F>>CCOC(=O)Cc1ccc(Nc2cc(CC)nc(-c3cccc(Cl)c3)n2)cc1,,C1COCCO1,O,[Li]O,,test
US20100273779A1,NN.O=C1CCCc2cc(OCCCCl)ccc21.O=CC(=O)O>>O=c1cc2c(n[nH]1)-c1ccc(OCCCCl)cc1CC2,,CC(=O)O,,O,O,test
US20070032478A1,Cc1nn(C)c(Cl)c1C(=O)O.Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3)c1>>Cc1nn(C)c(Cl)c1C(=O)Nc1cccc(C(=O)c2ccc3c(c2)NC(=O)C3)c1,,C1CCOC1,,O=S(Cl)Cl,,test
US20120184543A1,CC[C@H](NC(C)C)C(=O)OC.O=[N+]([O-])c1cnc(Cl)nc1Cl>>CC[C@@H](C(=O)OC)N(c1nc(Cl)ncc1[N+](=O)[O-])C(C)C,,C1CCCCC1,,ClCCl,O=C([O-])O.[Na+],test
US04001244,CCN(CC)CCN.COc1cc2c(cc1OC)C(c1ccccc1)N(C(=O)Cl)CC2>>CCN(CC)CCNC(=O)N1CCc2cc(OC)c(OC)cc2C1c1ccccc1,,O,,,,test
US20140296204A1,Brc1nccs1.OCc1ccccc1B(O)O>>OCc1ccccc1-c1nccs1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[Na+].[Na+],,test
US04982014,CC1CC(=O)CC(C)(C)C1.CCCCS.Oc1ccccc1.[OH-]>>Oc1cccc(-c2ccccc2O)c1,,O,,Cl,,test
US20150011533A1,Cc1ccc(S(=O)(=O)n2cc(NC(=O)c3cnn(Cc4ccccc4)c3)c3cc(-c4ccc(OCCCN(C)C)cc4)cnc32)cc1>>CN(C)CCCOc1ccc(-c2cnc3[nH]cc(NC(=O)c4cnn(Cc5ccccc5)c4)c3c2)cc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US04801705,C[Si](C)(C)Oc1ccc(N2CCN([Si](C)(C)C)C2=O)cc1O[Si](C)(C)C.O=C(N[C@H]1CNC1=O)OCc1ccccc1.O=C=NS(=O)(=O)Cl>>O=C(N[C@H]1CN(C(=O)NS(=O)(=O)N2CCN(c3ccc(O)c(O)c3)C2=O)C1=O)OCc1ccccc1,,CCOC(C)=O,,,,test
US20070021408A1,C1=CNc2ccccc2C=C1.CC=O>>CCN1C=CC=Cc2ccccc21,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04042706,CCO.Cc1ccc(-n2cc(-c3ccccc3)c(CC(=O)Cl)n2)cc1>>CCOC(=O)Cc1nn(-c2ccc(C)cc2)cc1-c1ccccc1,,c1ccccc1,,c1ccncc1,,test
US20110152297A1,CNC(=O)[C@@H]1C[C@@H](Oc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC)CCN1C(=O)OC(C)(C)C>>CNC(=O)[C@@H]1C[C@@H](Oc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC)CCN1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100063077A1,CC1(C)OB(c2cnc(Nc3ccccc3)nc2)OC1(C)C.OO>>Oc1cnc(Nc2ccccc2)nc1,,CO,,,,test
US20100204240A1,Cc1cccnc1Sc1cnc(Nc2nc([C@H]3COC4(CCCCC4)O3)ns2)c(Oc2cccnc2C)c1.Cl>>Cc1cccnc1Sc1cnc(Nc2nc([C@H](O)CO)ns2)c(Oc2cccnc2C)c1.Cl,,CCO,,,,test
US20040110945A1,COC(=O)Cc1ccc(N)c(O)c1F.S=C(n1ccnc1)n1ccnc1.c1ccc2c(c1)CCN2>>COC(=O)Cc1ccc2nc(N3CCc4ccccc43)oc2c1F,,C1CCOC1,,,,test
US20160194304A1,COC(=O)c1cc2c(cc1O)CCN(C(=O)OC(C)(C)C)C2.O=S(=O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>COC(=O)c1cc2c(cc1OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)CCN(C(=O)OC(C)(C)C)C2,,ClCCl,,CCN(CC)CC,O,test
US03983111,C1COCCN1.C[C@]12CC[C@@H](O)C[C@@H]1CC[C@@H]1[C@@H]2C(=O)C[C@]2(C)[C@@H](C(=O)CBr)CC[C@@H]12>>C[C@]12CC[C@@H](O)C[C@@H]1CC[C@@H]1[C@@H]2C(=O)C[C@]2(C)[C@@H](C(=O)CN3CCOCC3)CC[C@@H]12,,CCOCC,,C1CCOC1,,test
US20130210803A1,Cc1ccc2c(c1)CC(c1ccc(F)cc1)CN2.O=N[O-]>>Cc1ccc2c(c1)CC(c1ccc(F)cc1)CN2N=O,,CCO,O,Cl,,test
US20040133027A1,CC(C)=CC(=O)O.COc1ccccc1OS(C)(=O)=O>>COc1ccc(C(C)(C)CC(=O)O)cc1OS(C)(=O)=O,,O,,O=S(=O)(O)O,,test
US06124498,COc1ccc(CC(C)CC(=O)O)c(C)c1OC>>COc1cc2c(c(C)c1OC)CC(C)CC2=O,,ClCCl,,,,test
US20090137609A1,CCC(CC)(c1ccc(/C=C/C(O)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(-c2ccc(CC(=O)OC)c(Cl)c2)c(C)c1>>CCC(CC)(c1ccc(/C=C/C(O)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(-c2ccc(CC(=O)O)c(Cl)c2)c(C)c1,,C1CCOC1,CO,[Na+].[OH-],,test
US20150094297A1,CCOC(=O)c1csc(C(C)(C)c2ccccc2)n1>>CC(C)(c1ccccc1)c1nc(CO)cs1,,C1CCOC1,,CO,[BH4-].[Li+],test
US04971975,CCOC(=O)C1CCCNC1.ClCCBr>>CCOC(=O)C1CCCN(CCCl)C1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040053943A1,CC(C)(C)c1nc(I)c(-c2ccncc2)[nH]1.OB(O)c1cccc2ccccc12>>CC(C)(C)c1nc(-c2ccc3ccccc3c2)c(-c2ccncc2)[nH]1,,CCO,Cc1ccccc1,O,O=C([O-])O.[Na+],test
US20120289526A1,Cc1cccc(C)c1O.O=[N+]([O-])c1ccc(Cl)nc1>>Cc1cccc(C)c1Oc1ccc([N+](=O)[O-])cn1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04112224,C1CCOC1.CCOC(=O)N=NC(=O)OCC.O=C(O)c1ccccc1>>C1CCC(OC2CCCCO2)OC1,,CCCCCC,CCOC(C)=O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090270359A1,Cc1nn(Cc2ccc(N)cc2)c(C)c1-c1ccc(C#N)c(Cl)c1.O=S(=O)(Cl)c1ccc(F)cc1>>Cc1nn(Cc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2)c(C)c1-c1ccc(C#N)c(Cl)c1,,c1ccncc1,,Cl,,test
US04452789,CCOC(=O)c1cocc1C(=O)N(CC)c1ccc(OC)c(OC)c1>>CCN(C(=O)c1cocc1C(=O)O)c1ccc(OC)c(OC)c1,,CO,,Cl,[Na+].[OH-],test
US20150315114A1,COc1cccc2c1C[C@H]1C[C@@H](O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)[C@H](CC[C@H](CO[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@H]1C2>>COc1cccc2c1C[C@H]1C[C@@H](O[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)[C@H](CC[C@@H](O)CO)[C@H]1C2,,CCO,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20160168090A1,COC(CCn1cc(C(=O)C(F)(F)F)c2c(Cl)cccc21)OC>>O=CCCn1cc(C(=O)C(F)(F)F)c2c(Cl)cccc21,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20100160280A1,CC1(C)OB(C2=CCOCC2)OC1(C)C.Cc1cccnc1Nc1ccc(Oc2ncccc2Br)cc1>>Cc1cccnc1Nc1ccc(Oc2ncccc2C2=CCOCC2)cc1,,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US05639782,COc1cc(C(S)CS)cc(OC)c1OC.COc1cc(C=O)cc(C#N)c1OC>>COc1cc([C@@H]2SC[C@@H](c3cc(OC)c(OC)c(OC)c3)S2)cc(C#N)c1OC,,O,c1ccccc1,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US20140200227A1,COCc1cc(F)c(-c2nc(C(=O)Nc3cnc4c(c3N3C[C@@H](NC(=O)OC(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)C3)CCC4OC(C)=O)ccc2F)c(F)c1>>COCc1cc(F)c(-c2nc(C(=O)Nc3cnc4c(c3N3C[C@@H](NC(=O)OC(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](C)C3)CCC4O)ccc2F)c(F)c1,,CO,,C1CCOC1,[Na+].[OH-],test
US20150218187A1,COC=C1CC2(CCN(C(=O)OCc3ccccc3)CC2)C1>>O=CC1CC2(CCN(C(=O)OCc3ccccc3)CC2)C1,,CC#N,,Cl,,test
US20160264552A1,Nc1ccc(C(=O)N2CC[C@H](Nc3ncc(Cl)c(-c4cn(S(=O)(=O)c5ccccc5)c5ccccc45)n3)C2)cc1>>Nc1ccc(C(=O)N2CC[C@H](Nc3ncc(Cl)c(-c4c[nH]c5ccccc45)n3)C2)cc1,,C1COCCO1,,O=C(O)C(F)(F)F,[Na+].[OH-],test
US20070249031A1,CCCCO.CCN(C(C)C)C(C)C.CCOC(C)=O.Cc1cc(Nc2cc(Cl)nc(Sc3ccc(NC(=O)C4CC4)cc3F)n2)[nH]n1>>Cc1cc(Nc2cc(N3CC(O)(C4CC4)C3)nc(Sc3ccc(NC(=O)C4CC4)cc3F)n2)[nH]n1,,CCOC(C)=O,,Cl,,test
US20030109706A1,CC(C)(C)OC(=O)C(N)c1ccncc1>>CC(C)(C)OC(=O)C(N)C1CCNCC1,[Rh],,,,,test
US20020049243A1,CCCCOC(=O)Cl.CON(C)C(=O)[C@@H]1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)CN1>>CCCCOC(=O)N1C[C@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)C[C@H]1C(=O)N(C)OC,,C1CCOC1,,c1ccncc1,,test
US20020086874A1,C[Mg]Br.O=C1Nc2ccc(Br)cc2C1=O>>CC1(O)C(=O)Nc2ccc(Br)cc21,,C1CCOC1,,[Cl-].[NH4+],,test
US20040259923A1,COC(=O)c1nc(NC(C)=O)sc1-c1ccccc1>>CC(=O)Nc1nc(C=O)c(-c2ccccc2)s1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20040138065A1,C=CC=O.N#CC(C#N)Cc1ccc(C(F)(F)F)cc1>>N#CC(C#N)(CCC=O)Cc1ccc(C(F)(F)F)cc1,,C1CCOC1,,,,test
US20110257100A1,NC1CC1.Nc1ccc(Oc2ccnc3cc(-c4ccc(CN5CCOCC5=O)cn4)sc23)c(F)c1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>O=C(Nc1ccc(Oc2ccnc3cc(-c4ccc(CN5CCOCC5=O)cn4)sc23)c(F)c1)NC1CC1,,C1CCOC1,ClCCl,,,test
US04885367,CS(=O)(=O)Nc1ccc([N+](=O)[O-])cc1S(=O)C1CCCCC1.O=C(OO)c1cccc(Cl)c1>>CS(=O)(=O)Nc1ccc([N+](=O)[O-])cc1S(=O)(=O)C1CCCCC1,,ClC(Cl)Cl,,[Na+].[OH-],,test
US08507672B2,CS(=O)(=O)N=C(Oc1ccccc1)Oc1ccccc1.Nc1cccc(Br)c1>>CS(=O)(=O)N=C(Nc1cccc(Br)c1)Oc1ccccc1,,CC#N,,,,test
US20080194549A1,CCOC(C)=O.CN.CO.COCCCOc1cc(C(=O)N(C[C@@H]2CN(C(=O)OC(C)(C)C)C[C@H]2C=O)C(C)C)ccc1C>>CCOC(C)=O.CO.[NH4+].[OH-],,CCOC(C)=O,CO,[BH4-].[Na+],,test
US06303542B1,Nc1cc2c(cc1F)OCC(=O)N2.O=C(Cl)c1ccccc1[N+](=O)[O-]>>O=C1COc2cc(F)c(NC(=O)c3ccccc3[N+](=O)[O-])cc2N1,,ClCCl,,CCN(CC)CC,O,test
US20060173034A1,CCOC=C(C(=O)OCC)C(=O)OCC.COc1cc(N)ccc1OCc1ccccc1>>CCOC(=O)C(=CNc1ccc(OCc2ccccc2)c(OC)c1)C(=O)OCC,,CCO,,,,test
US20030225131A1,CC(C)(C)OC(=O)N1CCCCC1CCNc1nccc2oc(Cc3cc(Cl)ccc3-n3cncn3)nc12>>Clc1ccc(-n2cncn2)c(Cc2nc3c(NCCC4CCCCN4)nccc3o2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20140315889A1,COC(=O)c1ccc(Cn2c3c(c4cc(F)ccc42)C(=O)N(CCO)CC3)cc1.OC[C@H]1CCCN1>>COC(=O)c1ccc(Cn2c3c(c4cc(F)ccc42)C(=O)N(CCN2CCC[C@@H]2CO)CC3)cc1,,CC#N,,CCN(C(C)C)C(C)C,CS(=O)(=O)Cl,test
US05025036,COC(=O)c1cc(O)ccc1O.ICCCCCCc1cccc(OCc2ccccc2)c1OCc1ccccc1>>COC(=O)c1cc(OCCCCCCc2cccc(OCc3ccccc3)c2OCc2ccccc2)ccc1O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070021394A1,CCCCCO.N[C@@]1(C(=O)O)[C@H](OCc2ccc(Cl)c(Cl)c2)C[C@@H]2[C@H]1[C@@]2(F)C(=O)O>>CCCCCOC(=O)[C@@]1(F)[C@@H]2C[C@@H](OCc3ccc(Cl)c(Cl)c3)[C@@](N)(C(=O)O)[C@@H]21,,CCCCCO,,O=S(Cl)Cl,,test
US05866589,C=CC(C)(C)Nc1cccnc1N(C)C1CCN(C(=O)OC(C)(C)C)CC1>>CCC(C)(C)Nc1cccnc1N(C)C1CCN(C(=O)OC(C)(C)C)CC1,[Ni],CCO,,,,test
US20120252853A1,C[Si](C)(C)C#CNc1ccc(Br)c(F)c1>>Fc1cc2[nH]ccc2cc1Br,I[Cu]I,CN(C)C=O,O,,,test
US20150266879A1,Cc1cccc(F)c1NC(=O)[C@@H]1Cc2cccnc2N1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)C1CCOCC1>>CN[C@@H](C)C(=O)N[C@H](C(=O)N1c2ncccc2C[C@H]1C(=O)Nc1c(C)cccc1F)C1CCOCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04028319,CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1>>CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OC(C)(C)C)C(=O)O,,CO,,[Na+].[OH-],,test
US20080027068A1,CCOC(=O)c1csc(-c2ccc(C(C)(C)C)cc2)c1O.COCCl>>CCOC(=O)c1csc(-c2ccc(C(C)(C)C)cc2)c1OCOC,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US05932606,Cc1ncn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c1CN=[N+]=[N-]>>Cc1ncn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c1CN,,C1CCOC1,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130190316A1,CN(C)C=O.COc1cc(C2OCCO2)c(OCc2cccnc2Br)cn1>>COc1cc(C2OCCO2)c(OCc2cccnc2C#N)cn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,,,test
US05051524,CCCP(=O)(CCCN)OC(C)C>>CCCP(=O)(O)CCCN,,Cl,,,,test
US20110046133A1,CN(C)C=O.Clc1cc(Cl)cc(N2CCOCC2)c1>>O=Cc1c(Cl)cc(N2CCOCC2)cc1Cl,,C1CCOC1,,[Li]C(C)CC,,test
US05321037,CCN(CC)CC.O=C(Cl)OC(Cl)(Cl)Cl.OCC(O)COc1noc2ccc(Cl)cc12>>NC(=O)OCC(O)COc1noc2ccc(Cl)cc12,,c1ccccc1,,,,test
US20140038976A1,CB1OB(C)OB(C)O1.O=C1c2cccnc2C2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3Br)CCN12>>Cc1cc(C(F)(F)F)ccc1S(=O)(=O)N1CCN2C(=O)c3cccnc3C2C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20030162806A1,CC(C)(C)OC(=O)NCCCCN.Cc1cc(Cl)c([N+](=O)[O-])c(Cl)n1>>Cc1cc(NCCCCNC(=O)OC(C)(C)C)c([N+](=O)[O-])c(Cl)n1,,CN(C)C=O,,,,test
US20080306107A1,CCOC(=O)c1sc2nc(C)cc(C(F)(F)F)c2c1N>>Cc1cc(C(F)(F)F)c2c(N)c(C(=O)O)sc2n1,,O,,CO,[K+].[OH-],test
US20070167433A1,COCCCC1=CC(C)(C)Oc2ccc(CO)cc21.C[Si](C)(C)Br>>COCCCC1=CC(C)(C)Oc2ccc(CBr)cc21,,ClC(Cl)Cl,,,,test
US20090247555A1,CC(C)C[C@H](CO)Nc1nc(SC(C)c2ccccc2)nc2[nH]c(=O)sc12>>CC(C)C[C@H](CO)Nc1nc(S)nc2[nH]c(=O)sc12,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20090137595A1,Nc1cccc(O)c1.Nc1cn2nc(I)ccc2n1>>Nc1cccc(Oc2ccc3nc(N)cn3n2)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150018551A1,COCCOCn1nccc1[C@H]1CCC(F)(F)C[C@@H]1O.COc1ccc(CN(c2ccncn2)S(=O)(=O)c2cc(Cl)c(F)cc2F)c(OC)c1>>COCCOCn1nccc1[C@H]1CCC(F)(F)C[C@@H]1Oc1cc(F)c(S(=O)(=O)N(Cc2ccc(OC)cc2OC)c2ccncn2)cc1Cl,,O,,CN(C)C=O,[H-].[Na+],test
US09248117B2,CC(=O)SCCN1C(=O)NC(C)(C)C1=O>>CC1(C)NC(=O)N(CCS)C1=O,,CO,,O,[Na+].[OH-],test
US20130274305A1,CC(C)(C)OC(=O)CBr.O=[N+]([O-])c1ncc[nH]1>>CC(C)(C)OC(=O)Cn1ccnc1[N+](=O)[O-],,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US06825360B1,CC1CC(C)C(C)(C)c2cc(Br)c(O)cc21.CI>>COc1cc2c(cc1Br)C(C)(C)CCC2(C)C,,O,,CN(C)C=O,[H-].[Na+],test
US05220042,COCOc1cc(OC)c(OCOC)c(CCO[Si](C)(C)C(C)(C)C)c1OC>>COCOc1cc(OC)c(OCOC)c(CCO)c1OC,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20050032786A1,C[Si](C)(C)N=[N+]=[N-].N#CCCc1ccnc(-c2nc(=O)c3ccccc3s2)c1>>O=c1nc(-c2cc(CCc3nnn[nH]3)ccn2)sc2ccccc12,,Cc1ccccc1,,CCCC[Sn](=O)CCCC,,test
US20100239526A1,O=C(C(Cl)c1ccccc1)N1CCc2c(cnc3[nH]ncc23)C1.O=C1CCC(=O)N1Br>>O=C(C(Cl)c1ccccc1)N1CCc2c(cnc3[nH]nc(Br)c23)C1,,ClCCl,,,,test
US20020052369A1,CCOC(=O)c1cc2cc(CCCN(CC)CC)ccc2[nH]1>>CCN(CC)CCCc1ccc2[nH]c(CO)cc2c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20020119983A1,O=CCCc1cc(-c2cccs2)no1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>c1ccc(C(c2ccccc2)N2CCN(CCCc3cc(-c4cccs4)no3)CC2)cc1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20100331298A1,O=C(CCl)c1ccc2oc(=O)[nH]c2c1.O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1(CC2CC2)CCNCC1>>O=C(CN1CCC(CC2CC2)(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1)c1ccc2oc(=O)[nH]c2c1,,CN(C)C=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20150299189A1,CC(C)(C)OC(=O)c1cc(C2CC2)cnc1Nc1cccc2c1ccn2-c1ccccc1>>O=C(O)c1cc(C2CC2)cnc1Nc1cccc2c1ccn2-c1ccccc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110237791A1,COc1ccc(CN2C(=O)CC[C@@H]2/C=C(\c2ccc(C(C)(C)C)cc2)c2ccc(OC)c(=O)[nH]2)c(OC)c1>>COc1ccc(/C(=C/[C@H]2CCC(=O)N2)c2ccc(C(C)(C)C)cc2)[nH]c1=O,,O=C(O)C(F)(F)F,,COc1ccccc1,,test
US05750531,CNc1ccccc1.Cc1nc(N2CCc3ccccc3C2C)nc(Cl)c1C>>Cc1nc(N2CCc3ccccc3C2C)nc(N(C)c2ccccc2)c1C.Cl,,CN(C)C=O,,,,test
US20070249620A1,COc1ccc(C)cc1NC(=O)Nc1ccc(N2CCNCC2)cc1.COc1cccc(C)c1Nc1ccccc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc(C)cc1NC(=O)Nc1ccc(N2CCN(C(=O)Nc3c(C)cccc3OC)CC2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20140114067A1,CC(C)(C)c1cc(N)cc(C(C)(C)C)c1.O=C(O)Cn1c(-c2ccccc2)nc2ccccc21>>CC(C)(C)c1cc(NC(=O)Cn2c(-c3ccccc3)nc3ccccc32)cc(C(C)(C)C)c1,,CC#N,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US08173631B2,CCOC(=O)/C=C/c1cc(Cl)ccc1[C@@H](C)OC[C@H]1CO1>>CCOC(=O)CCc1cc(Cl)ccc1[C@@H](C)OC[C@H]1CO1,[Rh],CCO,,,,test
US20070004772A1,N#Cc1ccc(-c2ccnc(Cl)c2Br)cc1.NN>>N#Cc1ccc(-c2ccnc(NN)c2Br)cc1,,C1COCCO1,,,,test
US20130231328A1,CN(C(=O)OC(C)(C)C)C1CCC(Oc2ncnc3sc4c(c23)[C@H](CCO[Si](C)(C)C(C)(C)C)CC4)CC1>>CN(C(=O)OC(C)(C)C)C1CCC(Oc2ncnc3sc4c(c23)[C@H](CCO)CC4)CC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20020183330A1,Cc1ccc(S(=O)(=O)OC[C@H]2COc3ccc(N)c(N)c3O2)cc1.O=C(O)C(F)(F)F>>Cc1ccc(S(=O)(=O)OCC2COc3ccc4[nH]c(C(F)(F)F)nc4c3O2)cc1,,ClCCl,,Cl,Cl,test
US20120046278A1,Cc1cccc(N=C=O)c1.Nc1nc(N2CCNCC2)c2nc(CCc3ccc(F)cc3)oc2n1>>Cc1cccc(NC(=O)N2CCN(c3nc(N)nc4oc(CCc5ccc(F)cc5)nc34)CC2)c1,,ClCCl,,,,test
US20150141406A1,COc1nccc2c1c(-c1cnn(COCC[Si](C)(C)C)c1)nn2-c1c(F)cccc1C#N>>COc1nccc2c1c(-c1cn[nH]c1)nn2-c1c(F)cccc1C#N,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])[O-].[Na+].[Na+],test
US20020170125A1,Nc1c(N=O)cnn1CCn1ncc(N=O)c1N>>Nc1cnn(CCn2ncc(N)c2N)c1N,[Pd],O,,,,test
US04267176,CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnc(CNC(=O)OC(C)(C)C)s3)CS[C@H]12)c1cccc(NC=O)n1>>CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnc(CN)s3)CS[C@H]12)c1cccc(N)n1,,O=CO,,CO,Cl,test
US20140221361A1,C=C(C)[C@@H]1CC[C@]2(NC(=O)OC(C)(C)C)CC[C@]3(C)[C@H](CC[C@H]4[C@@]3(C)CC[C@H]3C(C)(C)C(c5ccc(C(=O)OC)c(F)c5)=CC[C@@]34C)[C@@H]12.O=C(OO)c1cccc(Cl)c1>>COC(=O)c1ccc(C2=CC[C@@]3(C)[C@@H](CC[C@]4(C)[C@@H]3CC[C@@H]3[C@H]5[C@H](C6(C)CO6)CC[C@]5(NC(=O)OC(C)(C)C)CC[C@]34C)C2(C)C)cc1F,,ClCCl,,,,test
US20040220234A1,CCC(CCN(C)C(=O)OC(C)(C)C)Oc1nc(C(F)(F)F)ccc1C#N.Cl>>CCC(CCNC)Oc1nc(C(F)(F)F)ccc1C#N.Cl,,C1COCCO1,,,,test
US04906658,BrCCCBr.Sc1ccccc1>>BrCCCSc1ccccc1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100063108A1,C=Cc1cc(C(=O)OC(C)(C)C)cc(C=C(C)C)n1>>CCc1cc(C(=O)OC(C)(C)C)cc(CC(C)C)n1,[Pd],CO,,,,test
US20060026774A1,Cc1cc([N+](=O)[O-])ccc1F.NCCNCCO>>Cc1cc([N+](=O)[O-])ccc1NCCNCCO,,O,,CN1CCCC1=O,O=C([O-])[O-].[K+].[K+],test
US20030199478A1,C1CCOC1.C1COCCN1.O=C(O)CCCc1ccc([N+](=O)[O-])cc1>>O=C(CCCc1ccc([N+](=O)[O-])cc1)N1CCCCC1,,C1CCOC1,,O=C([O-])O.[Na+],,test
US20070072865A1,CC1(C)OC(=O)N2CCNCC21.O=C=Nc1ccc(F)cc1>>CC1(C)OC(=O)N2CCN(C(=O)Nc3ccc(F)cc3)CC21,,C1CCOC1,,,,test
US20130053364A1,CCc1ccc(C)c(C(=O)O)c1O.O=C1CCC(=O)N1Br>>CCOC(=O)c1c(C)ccc(Br)c1O,,ClCCl,,CC(C)NC(C)C,,test
US20040010031A1,COc1ccccc1C1=C(Nc2ccc(CCNC(=O)OC(C)(C)C)cc2)C(=O)NC1=O>>COc1ccccc1C1=C(Nc2ccc(CCN)cc2)C(=O)NC1=O,O=C(O)C(F)(F)F,CCOC(C)=O,ClCCl,,,test
US20030100756A1,CSc1nc(Cl)c(C#N)c(Cl)n1.Nc1ccccc1>>CSc1nc(Cl)c(C#N)c(Nc2ccccc2)n1,,CCO,CCOCC,,,test
US20080194598A1,BrCCBr.Clc1ccccc1CBr.[Zn]>>Clc1ccccc1C[Zn+].[Br-],,CN(C)C=O,,C[Si](C)(C)Cl,,test
US05187179,CCCCc1nnc(N)n1Cc1ccc(-c2ccccc2C#N)cc1.O=CC(Br)c1ccccc1>>CCCCc1nn2c(-c3ccccc3)cnc2n1Cc1ccc(-c2ccccc2C#N)cc1,,CCO,,,,test
US20130252937A1,Cc1cc(OC(C)(C)C(=O)O)cc(C)c1Br>>Cc1cc(OC(C)(C)CO)cc(C)c1Br,,C1CCOC1,,Cl,O,test
US20080176747A1,CC(=O)N1CCN(C(C)=O)c2cnccc21.CN1CCN(C)c2cnccc21.CO>>CC(=O)N1c2ccncc2N(C(C)=O)C2CCCCC21,,CO,,,,test
US20120232052A1,Clc1ccc(OC2CCNCC2)cc1.O=C(O)c1ccc2cccc(O)c2n1>>O=C(c1ccc2cccc(O)c2n1)N1CCC(Oc2ccc(Cl)cc2)CC1,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090004185A1,CCI.CCOC(=O)NC(=S)Nc1cccc(C(C)C)c1>>CCOC(=O)NC(Nc1cccc(C(C)C)c1)SCC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080167355A1,CCCCCCN=C=O.O=c1[nH]c2ccccc2o1>>CCCC(CC)C(N)=O.O=c1[nH]c2ccccc2o1,,C1COCCO1,,,,test
US04948804,CC(C)OC1CCC(=O)N1.O=C(Cl)c1ccccc1>>CC(C)OC1CCC(=O)N1C(=O)c1ccccc1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US05591742,C=CC#N.CCOC(=O)C(C#N)NC=O>>CCOC(=O)c1nccc(C#N)c1N,,ClCCCl,,O=C(O)C(F)(F)F,,test
US09346797B1,O=C1CCC(F)(F)[C@](c2ccccc2F)(C(F)F)N1.O=[N+]([O-])O>>O=C1CCC(F)(F)[C@](c2cc([N+](=O)[O-])ccc2F)(C(F)F)N1,,O=C(O)C(F)(F)F,,O=S(=O)(O)O,[Na+].[OH-],test
US20120010189A1,CC(C)(C)OC(=O)N1CC(OS(C)(=O)=O)C1.Oc1ccc(CN2CCCC2)cc1>>CC(C)(C)OC(=O)N1CC(Oc2ccc(CN3CCCC3)cc2)C1,,CN(C)C=O,,O,[H-].[Na+],test
US20160235716A1,CN(C)c1ncc(C=O)s1.C[C@H](N)C1CC1>>C[C@H](NCc1cnc(N(C)C)s1)C1CC1,,CO,,[BH4-].[Na+],,test
US04997836,COc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)C(CO)C2)cc(OC)c1OC>>COc1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)C(C=O)C2)cc(OC)c1OC,,ClCCl,,CCN(CC)CC,CS(C)=O,test
US20090062251A1,CCS(=O)(=O)n1c2c(c3cc(C(=O)O)ccc31)CC(C1CCOCC1)CC2.OC1CCNCC1>>CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(O)CC4)ccc31)CC(C1CCOCC1)CC2,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110275608A1,COC(=O)c1ccc(-c2cccc(O)c2)o1>>O=C(O)c1ccc(-c2cccc(O)c2)o1,,CCO,,[Na+].[OH-],,test
US20060264460A1,N#Cc1cnc2ccc(N)cc2c1NC1CCCCCC1.NS(=O)(=O)c1ccc(C=O)cc1>>N#Cc1cnc2ccc(NCc3ccc(S(N)(=O)=O)cc3)cc2c1NC1CCCCCC1,,CCO,,[BH3-]C#N.[Na+],,test
US20140343032A1,CCOC(=O)CC1CC2COCC(C1O)N2C(=O)OC(C)(C)C>>CCOC(=O)CC1CC2COCC(C1=O)N2C(=O)OC(C)(C)C,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20040209921A1,CC(=O)OC(C)=O.Cc1ncccc1C(C)(C)O>>CC(=O)OC(C)(C)c1cccnc1C,CN(C)c1ccncc1,,,,,test
US20070105919A1,CC(C)(C)OC(=O)Nc1nc(-c2ccco2)c(C(=O)C2CCSCC2)s1.O=C(OO)c1cccc(Cl)c1>>CC(C)(C)OC(=O)Nc1nc(-c2ccco2)c(C(=O)C2CCS(=O)CC2)s1,,ClC(Cl)Cl,,O,,test
US20040236109A1,CC(=O)N1c2ccc(C(=O)O)cc2C(C)(c2ccccc2)CC1(C)C.COc1ccc(CCN)cc1>>COc1ccc(CCNC(=O)c2ccc3c(c2)C(C)(c2ccccc2)CC(C)(C)N3C(C)=O)cc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05576335,Nc1ccc(F)cc1[N+](=O)[O-].O=C(Cl)Oc1ccccc1>>O=C(Nc1ccc(F)cc1[N+](=O)[O-])Oc1ccccc1,,ClCCl,,CC(C)NC(C)C,,test
US20140155391A1,COC(=O)c1ccc(NS(C)(=O)=O)cc1OCC1CC1.ClCCN1CCOCC1>>COC(=O)c1ccc(N(CCN2CCOCC2)S(C)(=O)=O)cc1OCC1CC1,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100240717A1,COC(=O)CCc1c(C)cc(-c2nnc(-c3cc(CC(C)C)c(C)s3)o2)cc1C>>Cc1cc(-c2nnc(-c3cc(CC(C)C)c(C)s3)o2)cc(C)c1CCC(=O)O,,O=CO,,,,test
US20110144194A1,C#CCCCCCCCCCCOCc1ccccc1.COc1ccc(-c2oc3cc(OC)c(I)c(OC)c3c(=O)c2OC)cc1OC>>COc1ccc(-c2oc3cc(OC)c4cc(CCCCCCCCCCOCc5ccccc5)oc4c3c(=O)c2OC)cc1OC,[Cu]I,C1CCNCC1,,,,test
US04735940,CCOC(=O)C(Br)C(=O)OCC.S=C1NCCSc2ccsc21>>CCOC(=O)C(C(=O)OCC)=C1CSC2=C1SCCNC2,,ClCCl,,O=C([O-])O.[K+],,test
US20110046162A1,COC(=O)c1ccc(-c2nc(CCl)cs2)cc1.N#Cc1c([S-])nc2c(c1-c1ccccc1)CCC2>>COC(=O)c1ccc(-c2nc(CSc3nc4c(c(-c5ccccc5)c3C#N)CCC4)cs2)cc1,,O,,O=C([O-])O.[Na+],,test
US20070167452A1,OC1CCC2(CC1)OCCO2.Oc1ccc(Cl)cc1>>Clc1ccc(OC2CCC3(CC2)OCCO3)cc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080032995A1,C=CCOC(=O)c1cccc(COc2ccc3c(=O)c(-c4ccc(N)cc4)coc3c2)c1.CS(=O)(=O)Cl>>C=CCOC(=O)c1cccc(COc2ccc3c(=O)c(-c4ccc(NS(C)(=O)=O)cc4)coc3c2)c1,,ClCCl,,c1ccncc1,,test
US20130315825A1,COc1ccc(N)c(O)c1.O=[N+]([O-])c1ccc(Cl)c([N+](=O)[O-])c1>>COc1ccc(Nc2ccc([N+](=O)[O-])cc2[N+](=O)[O-])c(O)c1,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20100189773A1,Nc1cnc2[nH]ccc2c1.O=C(Cl)OCc1ccccc1>>O=C(Nc1cnc2[nH]ccc2c1)OCc1ccccc1,,C1CCOC1,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[Na+].[OH-],test
US20100256101A1,CCOC(=O)/C=C/c1ccc(C(F)(F)F)nc1>>O=C(O)/C=C/c1ccc(C(F)(F)F)nc1,,C1CCOC1,CCO,Cl,[Na+].[OH-],test
US20090029994A1,CCOC(=O)CCCBr.COc1ccc(C(C)C)cc1-c1ccc(C(F)(F)F)cc1CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccc(O)cn1>>CCOC(=O)CCCOc1ccc(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)Cc2cc(C(F)(F)F)ccc2-c2cc(C(C)C)ccc2OC)nc1,,CN(C)C=O,,O,[H-].[Na+],test
US20130287686A1,NCc1ccc(F)cc1.Nc1c([N+](=O)[O-])ccc(F)c1F>>Nc1c([N+](=O)[O-])ccc(NCc2ccc(F)cc2)c1F,II,CS(C)=O,,CCN(CC)CC,,test
US20080262041A1,C=O.N#Cc1cc(CN2CCC(C3(c4ccc(F)cc4)CCNCC3)C2=O)c2ccc(F)cc2c1>>CN1CCC(c2ccc(F)cc2)(C2CCN(Cc3cc(C#N)cc4cc(F)ccc34)C2=O)CC1,,CC#N,O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150361098A1,COC(CC(=O)NNc1nc(Cl)nc2c(Cl)cccc12)OC.COc1ccc(CN)c(OC)c1>>COc1ccc(CNc2nc(NNC(=O)CC(OC)OC)c3cccc(Cl)c3n2)c(OC)c1,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US05397793,Brc1cncnc1.N#CC(CCc1ccc(Cl)cc1)c1ccccc1>>N#CC(CCc1ccc(Cl)cc1)(c1ccccc1)c1cncnc1,,CN(C)C=O,,[H-].[Na+],,test
US20160108016A1,CCOC(=O)C(C)(C)c1cc(O)c(-c2cc(Cl)cc(Cl)c2)c(OC)c1.CCOC(=O)C(C)(C)c1cc(OC)c(-c2cc(Cl)cc(Cl)c2)c(OC)c1>>CCOC(=O)C(C)(C)c1cc(O)c(-c2cc(Cl)cc(Cl)c2)c(O)c1.CCOC(=O)C(C)(C)c1cc(O)c(-c2cc(Cl)cc(Cl)c2)c(OC)c1,,ClCCl,,BrB(Br)Br,,test
US05834463,Cl.c1ccc(CN2C[C@@H]3CCC[C@H]3Nc3ccccc32)cc1>>Cl.c1ccc(CN2C[C@@H]3CCC[C@H]3Nc3ccccc32)cc1,,CCO,,,,test
US20100152208A1,CNC.COC(=O)CCc1nc(Cl)c2sc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2n1>>COC(=O)CCc1nc(N(C)C)c2sc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2n1,,C1CCOC1,,,,test
US20090060968A1,CCOC(=O)C(Oc1ccc2cc(CN)[nH]c2c1)C(=O)OCC.O=S(=O)(Cl)c1ccccc1>>CCOC(=O)C(Oc1ccc2cc(CNS(=O)(=O)c3ccccc3)[nH]c2c1)C(=O)OCC,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20100222355A1,CC(C)(C)OC(=O)N1CCC(C#N)CC1.Cc1ccnc(F)c1>>Cc1ccnc(C2(C#N)CCN(C(=O)OC(C)(C)C)CC2)c1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20140349993A1,Cc1nc2ccc(-c3cccc(OC[C@H]4COC(C)(C)O4)c3)nn2c1C(=O)Nc1ccccn1>>Cc1nc2ccc(-c3cccc(OC[C@H](O)CO)c3)nn2c1C(=O)Nc1ccccn1,,CCO,,Cl,,test
US20040248854A1,CCCCCC(O)/C=C/[C@H]1CCCC(=O)N1CC#CCCCC(=O)OC>>CCCCCC(O)/C=C/[C@H]1CCCC(=O)N1C/C=C\CCCC(=O)OC,[Pd],CO,,[H][H],,test
US04394515,O=C(Cl)c1ccc2c(c1)Sc1ccccc1CC2=O.O=C(O)CCO>>O=C(O)CCOC(=O)c1ccc2c(c1)Sc1ccccc1CC2=O,,C1CCOC1,,[Na],,test
US20140086834A1,COc1cccc(OCCCl)c1.c1ccc(-c2cccnc2N2CCNCC2)nc1>>COc1cccc(OCCN2CCN(c3ncccc3-c3ccccn3)CC2)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090264432A1,CC(=O)NCCC[C@@](O)(c1ccc(F)c(-c2cccc(C)c2)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1>>CC(=O)NCCC=C(c1ccc(F)c(-c2cccc(C)c2)c1)[C@@H]1CCCN(C(=O)OC(C)(C)C)C1,,Cc1ccccc1,,CC[N+](CC)(CC)S(=O)(=O)N=C([O-])OC,,test
US04388233,Br.CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)Nc1ccc2cc(-c3ccccc3)c(=O)oc2c1>>Br.CC(C)C[C@H](N)C(=O)Nc1ccc2cc(-c3ccccc3)c(=O)oc2c1,,CC(=O)O,CCO,,,test
US20070232628A1,C=CCC(C(C)=O)C(=O)Nc1ccc(C(C)C)cc1>>CCCC(C(C)=O)C(=O)Nc1ccc(C(C)C)cc1,[Pd],CCO,CCOC(C)=O,N#N,,test
US20080153852A1,CC(C)(C)OC(=O)N[C@@H](Cc1ccc(-c2cc(O[C@@H](c3ccc(Br)cc3)C(F)(F)F)nc(N)n2)cc1)C(=O)O.OB(O)c1ccnc(F)c1>>CC(C)(C)OC(=O)N[C@@H](Cc1ccc(-c2cc(O[C@@H](c3ccc(-c4ccnc(F)c4)cc3)C(F)(F)F)nc(N)n2)cc1)C(=O)O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,O,,CC#N,O=C([O-])[O-].[Na+].[Na+],test
US20090017003A1,CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(CC(=O)O)CC4)ccc3OCC)nc12.CS(=O)(=O)SCCO>>CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(CC(=O)OCCSS(C)(=O)=O)CC4)ccc3OCC)nc12,CN(C)c1ccncc1,ClCCl,ClCCl,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20080249100A1,CC(C)(C)OC(=O)NCCNc1nc(NCc2ccc(Cl)c(Cl)c2)ncc1[N+](=O)[O-]>>CC(C)(C)OC(=O)NCCNc1nc(NCc2ccc(Cl)c(Cl)c2)ncc1N,[Ni],CO,,NN,,test
US20090023725A1,Brc1ccc2c(-c3ncccn3)n[nH]c2c1.CCNC(=O)c1cc(F)c(C)c(B2OC(C)(C)C(C)(C)O2)c1>>CCNC(=O)c1cc(F)c(C)c(-c2ccc3c(-c4ncccn4)n[nH]c3c2)c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CC(C)O,,O=C([O-])O.[Na+],,test
US20090042925A1,CC(C)=O.CC(C)Cn1c(CON)nc2c(N)nc3c(c21)CCCC3>>CC(C)=NOCc1nc2c(N)nc3c(c2n1CC(C)C)CCCC3,,CC#N,CO,,,test
US20050026174A1,COC(=O)c1cc(Cl)c(NC(C)=O)c([N+](=O)[O-])c1OC>>COC(=O)c1cc(Cl)c(N)c([N+](=O)[O-])c1OC,,CO,,,,test
US04438271,CC(O)c1c(F)cccc1F.O=S(Cl)Cl>>CC(Cl)c1c(F)cccc1F,,ClC(Cl)Cl,,,,test
US20100075947A1,Clc1nc2ccccc2nc1Cl.NS(=O)(=O)c1ccc(Cl)nc1>>O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccc(Cl)nc1,,CC(=O)O,,CS(C)=O,O=C([O-])[O-].[K+].[K+],test
US20130072677A1,CNC(=O)[C@](C)(C(=O)OC)N(C)C(=O)OC(C)(C)C.Cl>>CNC(=O)[C@@](C)(NC)C(=O)OC.Cl,,C1COCCO1,,,,test
US20060160790A1,O=C(NC1=CCC(=NN2CCCC2)C=C1)C(NC(=S)Nc1ccc(Br)cc1)c1ccccc1.c1c[nH]cn1>>C#Cc1ccc(NC(=S)NC(C(=O)NC2=CCC(=NN3CCCC3)C=C2)c2ccccc2)cc1,,C1CCOC1,,,,test
US05364844,Cl.N[C@@H](Cc1ccccc1)C(=O)O>>Cl.N[C@@H](CC1CCCCC1)C(=O)O,[Pt],,,O,[H][H],test
US04927968,CCCCOc1c(N)c(=O)c1=O.NCCCOc1cccc(C2OCCO2)c1>>Nc1c(NCCCOc2cccc(C3OCCO3)c2)c(=O)c1=O,,CO,,,,test
US20110166132A1,Cn1ccnc1.O=C(Cl)C(Cl)(Cl)Cl>>Cn1ccnc1C(=O)C(Cl)(Cl)Cl,,ClCCl,,CCN(CC)CC,,test
US20100113438A1,CC(=O)c1ccc(CO)cc1.CC(C)(C)OC(=O)/C=C/c1ccc(C=O)cn1>>CC(C)(C)OC(=O)/C=C/c1ccc(/C=C/C(=O)c2ccc(CO)cc2)cn1,,CCO,,[K+].[OH-],,test
US20150197511A1,Nc1ccnc(Cl)c1.O=[N+]([O-])c1ccc(F)c(F)c1>>O=[N+]([O-])c1ccc(Nc2ccnc(Cl)c2)c(F)c1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20140288123A1,Cc1nc(C)c(Br)c(O)n1.N#C[Zn]C#N>>Cc1nc(C)c(C#N)c(O)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,,,test
US20100016319A1,CC(C)(C)c1nnc(NC(=O)NCc2ccccc2O)s1.Clc1ccnc(Cl)n1>>CC(C)(C)c1nnc(NC(=O)NCc2ccccc2Oc2ccnc(Cl)n2)s1,,CC(C)=O,,[Na+].[OH-],,test
US04855310,O=C(O)CCBr.Sc1nnc(S)s1>>O=C(O)CCSc1nnc(S)s1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090137580A1,Clc1ncnc2cc[nH]c12.O=C(OCCBr)c1ccccc1>>O=C(OCCn1ccc2ncnc(Cl)c21)c1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080125437A1,Cn1c(Nc2ccc(I)cc2F)c(C(=O)Oc2ccccc2)c(=O)n(C)c1=O.NOC1COC(c2ccccc2)OC1>>Cn1c(Nc2ccc(I)cc2F)c(C(=O)NOC(CO)CO)c(=O)n(C)c1=O,,C1CCOC1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20060128790A1,COc1c(C)cc([N+](=O)[O-])cc1C>>COc1c(C)cc(N)cc1C,[Pd],CCO,,,,test
US20150175558A1,C1CNCCN1.CC(C)Oc1ccccc1-n1c(CCl)nc2ccccc2c1=O>>CC(C)Oc1ccccc1-n1c(CN2CCNCC2)nc2ccccc2c1=O,,C1CCOC1,,,,test
US20030176482A1,C[Mg]Br.O=C(Cn1ccnc1)c1cc(Cl)ccc1O>>CC(O)(Cn1ccnc1)c1cc(Cl)ccc1O,,C1CCOC1,,,,test
US20160046605A1,CCI.Oc1ccnc(Br)c1F>>CCOc1ccnc(Br)c1F,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030018067A1,CCOC(=O)COc1ccc2cc(Br)ccc2c1Cl.OB(O)c1cc2ccccc2o1>>CCOC(=O)COc1ccc2cc(-c3cc4ccccc4o3)ccc2c1Cl,,C1COCCO1,O,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20090264403A1,CN(C)C1CCNC1.O=[N+]([O-])c1ccc(F)c(Cl)c1>>CN(C)C1CCN(c2ccc([N+](=O)[O-])cc2Cl)C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090137609A1,CCC(CC)(c1ccc(/C=C/C2(O)CCCCC2)c(C)c1)c1ccc(-c2cncc(CC(=O)OC)c2)c(C)c1>>CCC(CC)(c1ccc(/C=C/C2(O)CCCCC2)c(C)c1)c1ccc(-c2cncc(CC(=O)O)c2)c(C)c1,,CO,,[Na+].[OH-],[Cl-].[NH4+],test
US20090137595A1,Cc1nn(C)cc1C(=O)O.Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)ccc1F>>Cc1nn(C)cc1C(=O)Nc1cc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)ccc1F,CN(C)C=O,C1CCOC1,CCOC(C)=O,O=C(Cl)C(=O)Cl,,test
US20090099182A1,COC(=O)CBr.OC1CCNCC1>>COC(=O)CN1CCC(O)CC1,,ClCCl,,CCN(CC)CC,O,test
US20030153580A1,CC(C)Oc1ccccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1.O=C(Cl)Cl>>CC(C)Oc1ccccc1C1=NC(c2ccc(Cl)cc2)C(c2ccc(Cl)cc2)N1C(=O)Cl,,ClCCl,,CCN(CC)CC,,test
US20140114086A1,C=C[C@@H](O)CCCCC.CC(C)(C)[Si](C)(C)Cl>>C=C[C@H](CCCCC)O[Si](C)(C)C(C)(C)C,,ClCCl,,O,c1c[nH]cn1,test
US20150336949A1,Cc1nn(Cc2cccc(F)c2)c(C)c1-c1c(C2CC2)n(C(=O)OC(C)(C)C)c2ncc(-c3ccc(N4CCN(C(=O)OC(C)(C)C)CC4)cc3)cc12>>Cc1nn(Cc2cccc(F)c2)c(C)c1-c1c(C2CC2)[nH]c2ncc(-c3ccc(N4CCNCC4)cc3)cc12,,CO,ClC(Cl)Cl,Cl,O=C([O-])O.[Na+],test
US04129654,CCOC([O-])[O-].Cn1c(=O)cc(NO)n(-c2ccccc2)c1=O>>Cn1c(=O)c2conc2n(-c2ccccc2)c1=O,,CN(C)C=O,,,,test
US20050065340A1,COc1cc(-c2nc3ccccc3o2)ccc1C.O=C1CCC(=O)N1Br>>COc1cc(-c2nc3ccccc3o2)ccc1CBr,,ClC(Cl)(Cl)Cl,,O=C(OOC(=O)c1ccccc1)c1ccccc1,,test
US04921863,C=O.Cc1ncnc2ccccc12.Cl.O=C(c1ccc(F)cc1)C1CCNCC1>>Cl.O=C(c1ccc(F)cc1)C1CCN(CCc2ncnc3ccccc23)CC1,,CCO,,,,test
US04181802,NCc1cccnc1.O=[N+]([O-])c1ccccc1Cl>>O=[N+]([O-])c1ccccc1NCc1cccnc1,,CCCCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20090186879A1,CCC(CC)c1ccc(Cl)c2nc(Nc3ccc(Br)cc3Cl)n(CCO)c12>>CCC(CC)c1ccc(Cl)c2nc3n(c12)CCN3c1ccc(Br)cc1Cl,,c1ccncc1,,CS(=O)(=O)Cl,,test
US20090291992A1,CC1(COc2cccc(C=O)c2)CCCCC1.O=C1CSC(=O)N1>>CC1(COc2cccc(C=C3SC(=O)NC3=O)c2)CCCCC1,,CCO,,C1CCNCC1,,test
US20140315220A1,CC(C)(C)OC(=O)NCCCOCCOCCOCCCNC(=O)C1(F)C#CCCCCC1>>NCCCOCCOCCOCCCNC(=O)C1(F)C#CCCCCC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090042929A1,CI.Cc1csc(CNC(=O)C23CC4CC(CC(C4)C2)C3)c1>>Cc1csc(CN(C)C(=O)C23CC4CC(CC(C4)C2)C3)c1,,CN(C)C=O,,[H-].[Na+],,test
US20080207654A1,CCCCc1nc(C)n(-c2cccc(Cl)c2)c(=O)c1Cc1ccc(-c2ccccc2C#N)cc1.O=C([O-])O.[NH3+]O>>CCCCc1nc(C)n(-c2cccc(Cl)c2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)cc1,,CCOC(C)=O,O,CS(C)=O,[Cl-].[Na+],test
US04894369,CCC(=O)Cl.CCC(=O)O[C@H]1[C@@H]([N+]2(C)CCCCC2)C[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@@H](N5CCOCC5)C[C@]4(C)[C@H]3CC[C@]12C.[Br-]>>CCC(=O)O[C@H]1C[C@@H]2CC[C@H]3[C@@H]4C[C@H]([N+]5(C)CCCCC5)[C@H](OC(=O)CC)[C@@]4(C)CC[C@@H]3[C@@]2(C)C[C@@H]1N1CCOCC1.[Br-],,ClCCl,,,,test
US20030199440A1,CC(C)(C)OC(=O)[C@@H]1CC[C@H](NS(=O)(=O)c2ccc3c(Cl)cnc(NC(=N)N)c3c2)CC1.Cl>>Cl.N=C(N)Nc1ncc(Cl)c2ccc(S(=O)(=O)N[C@H]3CC[C@@H](C(=O)O)CC3)cc12,,CCOC(C)=O,,,,test
US05571833,CCCBr.Cc1c([N+](=O)[O-])ccc(O)c1Cl>>CCCOc1ccc([N+](=O)[O-])c(C)c1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20110281865A1,O=Cc1ccc(-c2ccc3nnn(Cc4ccc(F)cc4)c3n2)cc1>>OCc1ccc(-c2ccc3nnn(Cc4ccc(F)cc4)c3n2)cc1,,CO,,[BH4-].[Na+],,test
US20130109693A1,Clc1cnc2c(Cl)nc(Cl)nc2c1.NCc1ccccc1>>Clc1cnc2c(NCc3ccccc3)nc(Cl)nc2c1,,C1CCOC1,,CCN(CC)CC,,test
US20150119412A1,COC(=O)c1ccc(-c2ccc(F)cc2)cc1OC(C)C.O=c1[nH]c(=O)n(Br)c(=O)n1Br>>COC(=O)c1cc(Br)c(-c2ccc(F)cc2)cc1OC(C)C,,O,,CN(C)C=O,,test
US04296120,C=C(CC(=O)O)C(=O)O.CCCCCCCCNC(=O)C(C)=Cc1cccc(N)c1>>CCCCCCCCNC(=O)C(C)=Cc1cccc(N2CC(C(=O)O)CC2=O)c1,,CCOC(C)=O,,,,test
US20120252818A1,CN1CCNCC1.COc1cc(OC)nc(Cl)n1>>COc1cc(OC)nc(N2CCN(C)CC2)n1,,CN(C)C=O,,,,test
US20100256156A1,Br[Mg]C1CCCCC1.Cc1cn(-c2cccc(C(F)(F)F)c2)cc1C=O>>Cc1cn(-c2cccc(C(F)(F)F)c2)cc1C(O)C1CCCCC1,,C1CCOC1,,[Cl-].[NH4+],,test
US20090286974A1,COC(=O)Cc1cccc(CBr)c1.NC1CCN(c2nc3ccc(Cl)cc3s2)CC1>>COC(=O)Cc1cccc(CNC2CCN(c3nc4ccc(Cl)cc4s3)CC2)c1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20100184815A1,COC(c1ccc(C)cc1)(C(F)(F)F)C(F)(F)F.O=C1CCC(=O)N1Br>>COC(c1ccc(CBr)cc1)(C(F)(F)F)C(F)(F)F,O=C(OOC(=O)c1ccccc1)c1ccccc1,ClC(Cl)(Cl)Cl,,,,test
US20160214934A1,C=CS(=O)(=O)Oc1ccccc1.Cc1cc(OCCCc2c[nH]c3ccccc23)cc(C)c1Cl>>Cc1cc(OCCCc2cn(CCS(=O)(=O)Oc3ccccc3)c3ccccc23)cc(C)c1Cl,,CN(C)C=O,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20110021501A1,CCc1[nH]c2ccc(F)cc2c1C1=CCNCC1>>CCc1[nH]c2ccc(F)cc2c1C1CCNCC1,[Pd],CO,,,,test
US20160039773A1,CC1(CBr)COC1.COC(=O)/C=C/n1nn[nH]c1=O>>COC(=O)/C=C/n1nnn(CC2(C)COC2)c1=O,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130018055A1,CC1(C)OB(c2ccc3c(c2)CC[C@@H]3NC(=O)C2(NC(=O)C(F)(F)F)CC2)OC1(C)C.Cc1nc(-c2c(F)cc(Cl)cc2Br)no1>>Cc1nc(-c2c(F)cc(Cl)cc2-c2ccc3c(c2)CC[C@@H]3NC(=O)C2(NC(=O)C(F)(F)F)CC2)no1,Cl[Pd]Cl,CS(C)=O,O,O=C([O-])[O-].[Na+].[Na+],,test
US20050009829A1,COC(=O)c1cccc2c1nc(C(=O)NC1CCN(C(C)C)CC1)n2Cc1cccc(OC)c1.COC(=O)c1cccc2nc(C(=O)NC3CCN(C(C)C)CC3)n(Cc3cccc(OC)c3)c12>>COc1cccc(Cn2c(C(=O)NC3CCN(C(C)C)CC3)nc3c(C(=O)O)cccc32)c1.COc1cccc(Cn2c(C(=O)NC3CCN(C(C)C)CC3)nc3cccc(C(=O)O)c32)c1,,CO,,Cl,[Li+].[OH-],test
US20110281884A1,COC(=O)c1cc(Cl)c[n+]([O-])c1Cl.C[Si](C)(C)C#N>>COC(=O)c1cc(Cl)c(C#N)nc1Cl,,CC#N,,CCN(CC)CC,,test
US20090149437A1,CCOC(=O)c1c(Nc2ccc(I)cc2F)sc2ncccc12.N>>NC(=O)c1c(Nc2ccc(I)cc2F)sc2ncccc12,,CCO,,ClCCl,,test
US20060189602A1,CC(C)CCn1nc(C(C)C)c(O)c(C2=NS(=O)(=O)c3cc([N+](=O)[O-])ccc3N2)c1=O>>CC(C)CCn1nc(C(C)C)c(O)c(C2=NS(=O)(=O)c3cc(N)ccc3N2)c1=O,[Ni],C1CCOC1,CO,NN,,test
US20120015980A1,COC(=O)c1cc(C2CO2)nn1-c1ncccc1Cl.FC(F)(F)c1nn[nH]n1>>COC(=O)c1cc(C(O)Cn2nnc(C(F)(F)F)n2)nn1-c1ncccc1Cl,,C1CCOC1,CC(=O)O,O,[H-].[Na+],test
US06498172B1,COC(=O)C(C)Cc1cccc(C#N)c1.[NH4+].[OH-]>>COC(=O)C(C)Cc1cccc(CN)c1.[NH4+].[OH-],[Pd],CCOC(C)=O,CO,,,test
US20060234997A1,O=C1CCCc2ccc(OCCCCOC3CCCCO3)nc2N1>>O=C1CCCc2ccc(OCCCCO)nc2N1,,CO,,Cl,O=C([O-])O.[Na+],test
US20120178751A1,CC(C)(C)C(=O)Nc1cc(-c2cn3nc(Cl)ccc3n2)ccc1C(F)(F)F.CN>>CNc1ccc2nc(-c3ccc(C(F)(F)F)c(NC(=O)C(C)(C)C)c3)cn2n1,,C1CCOC1,,,,test
US20110060121A1,C=CCOC(=O)[C@@H](CO[C@@H]1OC2COC(c3ccccc3)O[C@H]2[C@H](O)[C@@H]1NC(C)=O)NC(=O)OCC1c2ccccc2-c2ccccc21.O=C(O)CSC(c1ccccc1)(c1ccccc1)c1ccccc1>>C=CCOC(=O)[C@@H](CO[C@@H]1OC2COC(c3ccccc3)O[C@H]2[C@H](OC(=O)CSC(c2ccccc2)(c2ccccc2)c2ccccc2)[C@@H]1NC(C)=O)NC(=O)OCC1c2ccccc2-c2ccccc21,CN(C)c1ccncc1,ClCCl,,CC(C)N=C=NC(C)C,,test
US20150057271A1,CCN(CC)C(=O)CCl.COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(c2)OCCN3)cc1>>CCN(CC)C(=O)CN1CCOc2cc(S(=O)(=O)Nc3nccs3)ccc21,,CN(C)C=O,,[H-].[Na+],,test
US20060205772A1,CC(C)CN.COC(=O)c1ccc(C(=O)Cl)c([N+](=O)[O-])c1>>COC(=O)c1ccc(C(=O)NCC(C)C)c([N+](=O)[O-])c1,,ClCCl,,,,test
US20150210722A1,CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)n(-c2cccc(CP(C)(C)=O)c2)n1.Nc1cc(OCCN2CCOCC2)cc(C(F)(F)F)c1>>CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(OCCN5CCOCC5)cc(C(F)(F)F)c4)n3)c3ccccc23)n(-c2cccc(CP(C)(C)=O)c2)n1,,CN(C)C=O,,CCN(CC)CC,O,test
US20110015157A1,C=CCC(O)(CCCl)c1ccccc1.NCCc1ccccc1>>C=CCC(O)(CCNCCc1ccccc1)c1ccccc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130090342A1,Cc1cccc([N+](=O)[O-])c1F.Nc1ccc(Cl)nn1>>Cc1cccc([N+](=O)[O-])c1Nc1ccc(Cl)nn1,,CN(C)C=O,,[H-].[Na+],,test
US20150031673A1,BrC1COC1.Brc1cn[nH]c1>>Brc1cnn(C2COC2)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090253687A1,Nn1cnnc1S.O=C1COc2ccc(C(=O)C(Br)c3ccc(Cl)cc3)cc2N1>>O=C1COc2ccc(C3=Nn4cnnc4SC3c3ccc(Cl)cc3)cc2N1,,Cc1ccccc1,,CCO,,test
US20150252038A1,C[Si](C)(C)C(F)F.O=Cc1cc(Cl)cc(Cl)c1>>OC(c1cc(Cl)cc(Cl)c1)C(F)F,,CCOC(C)=O,CN(C)C=O,[Cs+].[F-],,test
US20150025087A1,COc1ncnc(Cn2cc(C(=O)O)c3ncc(C)cc32)c1C.C[C@@H](O)CN>>COc1ncnc(Cn2cc(C(=O)NC[C@@H](C)O)c3ncc(C)cc32)c1C,,ClCCl,,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(CC)CC,test
US20060211717A1,CN(C)CCN.COc1cc2nccc(Oc3cc(C)c(N)cc3C)c2cc1OC.S=C(Cl)Cl>>COc1cc2nccc(Oc3cc(C)c(NC(=S)NCCN(C)C)cc3C)c2cc1OC,,CCOC(C)=O,CN(C)C=O,CCN(CC)CC,,test
US20130053397A1,COc1nc(CO)cc(C)c1C#N>>COc1nc(CO)cc(C)c1CN,[Ni],CC(=O)O,CCO,,,test
US20150175602A1,BrCc1ccccc1.CC(C)Nc1nc2cnccc2nc1N1CCC(Oc2ccc(F)cc2F)CC1>>CC(C)Nc1nc2c[n+](Cc3ccccc3)ccc2nc1N1CCC(Oc2ccc(F)cc2F)CC1.[Br-],,CC#N,,,,test
US20100120785A1,OO.c1ccc(-c2cccnc2)cc1>>[O-][n+]1cccc(-c2ccccc2)c1,,CC(=O)O,,,,test
US20090306041A1,CC(C)(C)[SiH2]OC(C)(C)c1c(Br)cccc1N1C(=O)c2ccc(C3CC3)cc2CC1O>>CC(C)(C)[SiH2]OC(C)(C)c1c(Br)cccc1-n1ccc2cc(C3CC3)ccc2c1=O,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20150376160A1,CCOC(=O)C1(c2ccc(-c3ccc(-c4sccc4C(=O)OC(C)(C)C)cc3OC)cc2)CC1.O=S(=O)(c1ccccc1)N(F)S(=O)(=O)c1ccccc1>>CCOC(=O)C1(c2ccc(-c3ccc(-c4sc(F)cc4C(=O)OC(C)(C)C)cc3OC)cc2)CC1,,C1CCOC1,CCOC(C)=O,[Cl-].[NH4+],CC(C)[N-]C(C)C.[Li+],test
US06326369B1,COC1=C(OC)C(=O)C2=C(CCC(CCO)CC2)C1=O.COc1cc(O)cc(OC)c1OC>>COC1=C(OC)C(=O)C2=C(CCC(CCOc3cc(OC)c(OC)c(OC)c3)CC2)C1=O,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080171732A1,CC(C)OC(=O)c1cc(C#N)c(N2CCC(C(=O)O)CC2)nc1C#N.NS(=O)(=O)Cc1ccccc1>>CC(C)OC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)Cc3ccccc3)CC2)nc1C#N,,ClCCl,,CCN(C(C)C)C(C)C,Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.F[P-](F)(F)(F)(F)F,test
US05147876,COC(=O)c1cnc(NC(C)C)nc1C.O=C(O)/C=C\C(=O)O>>COC(=O)c1cnc(NC(C)C)nc1C.O=C(O)/C=C\C(=O)O,,CCO,ClC(Cl)Cl,,,test
US06245761B1,Fc1ccc(Br)cc1CBr.OCCCCO>>OCCCCOCc1cc(Br)ccc1F,,CN(C)C=O,,[H-].[Na+],,test
US20160256438A1,CC(C)(C)CCn1ccnc1C=O.NO>>CC(C)(C)CCn1ccnc1C=NO,,O,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US04948804,CCCCCCOC1CCC(=O)N1.O=C(Cl)c1ccccc1>>CCCCCCOC1CCC(=O)N1C(=O)c1ccccc1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20060235030A1,Cc1ccc(C(=O)NC(C)C)cc1-c1nc(NCCN(CC(C)(C)C)C(=O)[O-])nc2c1CNC(=O)N2c1c(F)cccc1F>>CNCCNc1nc(-c2cc(C(=O)NC(C)C)ccc2C)c2c(n1)N(c1c(F)cccc1F)C(=O)NC2,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160159820A1,CCN1CCN(Cc2ccc(C(=O)OC)cc2C)CC1>>CCN1CCN(Cc2ccc(C(=O)O)cc2C)CC1,,CO,O,Cl,[Na+].[OH-],test
US20130045169A1,O=C(c1ccccc1)c1cccc(O)c1.OCc1ccc(CC2OCCO2)cc1>>O=C(c1ccccc1)c1cccc(OCc2ccc(CC3OCCO3)cc2)c1,,C1CCOC1,CCOC(C)=O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US06500846B1,CC(=O)Nc1ccc2oc(-c3ccc4c(c3)OCO4)c(O)c(=O)c2c1>>CC(=O)Nc1ccc2oc(-c3ccc(O)c(O)c3)c(O)c(=O)c2c1,,ClCCl,,BrB(Br)Br,,test
US20150315198A1,CCOC(=O)C1CCCN(C(=O)OC(C)(C)C)CC1>>CC(C)(C)OC(=O)N1CCCC(CO)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04999378,COC(=O)c1ccc(OCCCN(C(=O)c2ccc3c(c2)OCO3)c2ccc(C(C)(C)C)cc2)cc1>>CC(C)(C)c1ccc(N(CCCOc2ccc(C(=O)O)cc2)C(=O)c2ccc3c(c2)OCO3)cc1,,CO,O,Cl,[Na+].[OH-],test
US20040260088A1,CN(C)CCN.N#Cc1ccc(Cl)cc1Oc1cccc(C=O)c1.O=C(O)/C=C/C(=O)O>>CN(C)CCNCc1cccc(Oc2cc(Cl)ccc2C#N)c1.O=C(O)/C=C/C(=O)O,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US20050123790A1,Brc1ccccc1-c1ccccc1.O=C(c1ccccc1)c1ccccc1>>OC(c1ccccc1)(c1ccccc1)c1ccccc1-c1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US20150011546A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cc(C)nc(OC)c1C#N>>COc1cc(C)nc(OC)c1CNC(=O)OC(C)(C)C,[Ni],C1CCOC1,CO,,,test
US04480135,COc1ccc(CO)cc1.OO>>COc1ccc(C=O)cc1.OO,,CC(C)=O,,,,test
US05359066,C=O.CCOC(=O)c1cn(NC)c2c(F)c(F)c(F)cc2c1=O>>CCOC(=O)c1cn(N(C)CO)c2c(F)c(F)c(F)cc2c1=O,,O,,,,test
US04099000,CC(=O)OCC1(O)CSC=NC1C(=O)OCc1ccc([N+](=O)[O-])cc1.[N-]=[N+]=NCC(=O)Cl>>CC(=O)OCC1(O)CS[C@@H]2[C@@H](N=[N+]=[N-])C(=O)N2C1C(=O)OCc1ccc([N+](=O)[O-])cc1,,ClCCl,,CCN(CC)CC,,test
US05140011,CCCCNC(=O)/C=C/[C@@H](C[C@@H]1OC(C)(C)N(C(=O)OC(C)(C)C)[C@H]1CC1CCCCC1)C(C)C>>CCCCNC(=O)/C=C/[C@@H](C[C@H](O)[C@@H](N)CC1CCCCC1)C(C)C,,CO,,Cl,,test
US20110118245A1,Cc1cc(-n2nc(C(C)(C)C)cc2N)ccn1.O=C(Cl)Oc1ccccc1>>Cc1cc(-n2nc(C(C)(C)C)cc2NC(=O)Oc2ccccc2)ccn1,,ClCCl,,O=C([O-])[O-].[K+].[K+],,test
US20120035407A1,CS(=O)(=O)Cl.Cc1ccc2nc(-c3nc(C#CCN)cnc3N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n(C(=O)OC(C)(C)C)c2c1>>Cc1ccc2nc(-c3nc(C#CCNS(C)(=O)=O)cnc3N)[nH]c2c1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20150353553A1,C[C@@H]1CC[C@@H](Cn2c(Br)nc3nc(C(=N)NO)nc(N[C@H](C)C4CCC4)c32)CC1.O=C(n1ccnc1)n1ccnc1>>C[C@@H]1CC[C@@H](Cn2c(Br)nc3nc(-c4noc(=O)[nH]4)nc(N[C@H](C)C4CCC4)c32)CC1,,CC#N,ClCCl,C1CCC2=NCCCN2CC1,,test
US20160115125A1,Cn1cc(S(=O)(=O)Cl)cc1C(=O)Cl.N#Cc1cccc(N)c1>>Cn1cc(S(=O)(=O)Cl)cc1C(=O)Nc1cccc(C#N)c1,,Cc1ccccc1,,,,test
US20030069287A1,CCCOCc1onc(-c2ccccc2)c1-c1ccc(S(=O)(=O)NC(=O)CC)cc1>>CCC(=O)NS(=O)(=O)c1ccc(-c2c(-c3ccccc3)noc2CO)cc1,,CO,,Cl,[Na+].[OH-],test
US20100152166A1,COC(=O)CC(=O)C1CC1.ClON=Cc1c(Cl)cccc1Cl>>COC(=O)c1c(-c2c(Cl)cccc2Cl)noc1C1CC1,,CCO,CCOC(C)=O,CCN(CC)CC,,test
US05236918,CCCOc1ccc(-c2ccc(=O)[nH]n2)cc1OC.O=P(Cl)(Cl)Cl>>CCCOc1ccc(-c2ccc(Cl)nn2)cc1OC,,O=P(Cl)(Cl)Cl,,Cl,,test
US20030166639A1,CC(C)(C)OC(=O)Nc1cc(C(F)(F)F)c(Cl)cc1NC(=O)CC(=O)c1cccc(-c2cccnc2)c1>>O=C1CC(c2cccc(-c3cccnc3)c2)=Nc2cc(C(F)(F)F)c(Cl)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070078121A1,CC(C)(C)c1cc(N)n(-c2ccc3c(c2)C(=O)CC3)n1.O=C=Nc1cccc(Cl)c1Cl>>CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)n(-c2ccc3c(c2)C(=O)CC3)n1,,C1CCOC1,,O,,test
US20060030612A1,C1CCNCC1.FC(F)(F)c1cccc2c(Cl)n(-c3ccccc3)nc12>>FC(F)(F)c1cccc2c(N3CCCCC3)n(-c3ccccc3)nc12,,CS(C)=O,,O,,test
US04877779,C#CCCCC=O.SCCCS>>C#CCCCC1SCCCS1,,ClCCl,,,,test
US20160168156A1,CC(C)(C)OC(=O)N1CCCC(n2cc(-c3cnn4ccc(N5CCC[C@@H]5c5cc(F)ccc5F)nc34)nn2)C1>>Fc1ccc(F)c([C@H]2CCCN2c2ccn3ncc(-c4cn(C5CCCNC5)nn4)c3n2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100144787A1,CCc1nc2c(F)ccc(OCC(=O)OC)c2c(OC(F)F)c1Cc1ccc(NS(=O)(=O)CC)cc1>>CCc1nc2c(F)ccc(OCC(=O)O)c2c(OC(F)F)c1Cc1ccc(NS(=O)(=O)CC)cc1,,CO,O,CC(=O)O,[Na+].[OH-],test
US04144338,CN(C)CCN.Cc1ncc(Cl)nc1C>>Cc1ncc(NCCN(C)C)nc1C,,O,,[Na+].[OH-],,test
US20120122817A1,CCn1cc(C(=O)OCCCO)c(=O)c2cc(Br)cnc21.O=P(O)(OCc1ccccc1)OCc1ccccc1>>CCn1cc(C(=O)OCCCOP(=O)(OCc2ccccc2)OCc2ccccc2)c(=O)c2cc(Br)cnc21,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130331571A1,CCC[C@H](N)CO.COc1ccc(N=C=O)cc1>>CCC[C@@H](CO)NC(=O)Nc1ccc(OC)cc1,,C1CCOC1,,CO,,test
US20140315963A1,CC(C)(C)OC(=O)Cn1c(=O)oc2ccc(Cl)cc21>>O=C(O)Cn1c(=O)oc2ccc(Cl)cc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US04258120,C=CCc1c(-c2ccccc2)cc2ccc([N+](=O)[O-])cc2c1O>>CCCc1c(-c2ccccc2)cc2ccc(N)cc2c1O,[Pd],CC(C)=O,,CCO,[H][H],test
US20120322785A1,CI.Fc1c(I)ccnc1Cl>>Cc1c(I)cnc(Cl)c1F,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US20060073971A1,O=C(c1cccnc1)c1c(Cc2ccc(Cl)cc2Cl)noc1-c1ccccc1Cl>>OC(c1cccnc1)c1c(Cc2ccc(Cl)cc2Cl)noc1-c1ccccc1Cl,,C1CCOC1,CCOC(C)=O,[BH4-].[Na+],,test
US20110039895A1,C=C[Sn](CCCC)(CCCC)CCCC.COC(=O)c1c(Br)ccc([N+](=O)[O-])c1[N+](=O)[O-]>>C=Cc1ccc([N+](=O)[O-])c([N+](=O)[O-])c1C(=O)OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,,,test
US20060235030A1,CN(C)CCN.CS(=O)c1nc(Cl)c2c(n1)N(c1c(F)cccc1F)C(=O)NC2>>CN(C)CCNc1nc(Cl)c2c(n1)N(c1c(F)cccc1F)C(=O)NC2,,ClCCl,,CCN(CC)CC,,test
US20100261755A1,CCOC(=O)CC(=O)C1CCN(C(=O)OC)C(c2cccc(C(C)(C)C)c2)C1.NO>>COC(=O)N1CC[C@H](c2cc(=O)[nH]o2)C[C@@H]1c1cccc(C(C)(C)C)c1,,CO,O,Cl,[Na+].[OH-],test
US20040127574A1,O=C(O)C(Cc1ccc(Cl)c(OC(F)(F)C(F)F)c1)C(O)c1ccc(F)cc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>O=C1NC(Cc2ccc(Cl)c(OC(F)(F)C(F)F)c2)C(c2ccc(F)cc2)O1,,C1CCOC1,,CCN(CC)CC,O,test
US04304770,CCCCCCN.CI.S=C=S>>CCCCCCNC(=S)SC,,O,,[Na+].[OH-],,test
US20060142572A1,COC(=O)CNc1nc(Cl)ncc1Cl>>O=C(O)CNc1nc(Cl)ncc1Cl,,C1CCOC1,O,Cl,[Li]O,test
US04954512,C1COCCO1.CC(C)(C)OC(=O)NC[C@H]1CC[C@H](C(=O)NC(=O)[C@@H](N)Cc2ccccc2)CC1.Cl>>CN(C)C(=O)[C@@H](N)Cc1ccccc1.Cl,,C1COCCO1,,,,test
US05302720,CS(=O)(=O)c1ccc(-c2ccccc2[N+](=O)[O-])cc1>>CS(=O)(=O)c1ccc(-c2ccccc2N)cc1,,CCO,,,,test
US05516774,CCOC(=O)c1ccc([N+](=O)[O-])c(Cn2cccc2C=O)c1>>CCOC(=O)c1ccc2c(c1)Cn1cccc1CN2,[Pd],CCO,,[H][H],,test
US20090099173A1,C[C@@H]1CNCCN1c1nnc(Cl)c2ccncc12.O=C(O)C1CCC(F)(F)CC1>>C[C@@H]1CN(C(=O)C2CCC(F)(F)CC2)CCN1c1nnc(Cl)c2ccncc12,,CN(C)C=O,,CCN(CC)CC,O=C1OCCN1P(=O)(Cl)N1CCOC1=O,test
US20050020605A1,CCO/N=C(\c1ccc(Br)cc1)C1CCN(C2(C)CCNCC2)CC1.O=C(O)c1ccnc2ccccc12>>CCO/N=C(\c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3ccnc4ccccc34)CC2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20040082784A1,CCC(Nc1nccc(-c2ccc(OC(F)F)cc2Cl)c1N)C1CC1.COC(=O)C(C)=O>>CCC(C1CC1)n1c(=O)c(C)nc2c(-c3ccc(OC(F)F)cc3Cl)ccnc21,,CCO,,,,test
US20070254909A1,COc1nc(C)c(I)c(C)c1C#N.OB(O)c1ccccc1>>COc1nc(C)c(-c2ccccc2)c(C)c1C#N,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCO,,Cc1ccccc1,O=C([O-])[O-].[K+].[K+],test
US20080125468A1,CNOC.COC(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)nc1>>CON(C)C(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)nc1,,C1CCOC1,,CC(C)[Mg]Cl,Cl,test
US20100286118A1,CC(C)(C)OC(=O)NC1(C(=O)N[C@H](C#N)Cc2ccc(I)cc2)CCOCC1.NC(=O)c1ccc(B(O)O)cc1F>>CC(C)(C)OC(=O)NC1(C(=O)N[C@H](C#N)Cc2ccc(-c3ccc(C(N)=O)c(F)c3)cc2)CCOCC1,,CC#N,O,CC(=O)[O-].[K+],,test
US20110059034A1,O=C1O[C@H]([C@@H](O)CO)C(O)=C1O.OCC1CO1>>O=C1O[C@H]([C@@H](O)CO)C(O)=C1OCC(O)CO,,CO,,O,O=C([O-])O.[Na+],test
US20050250836A1,Cn1ccc2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O.O=C1CCC(=O)N1Br>>Cn1cc(Br)c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O,,C1CCOC1,,CCOC(C)=O,,test
US20050014812A1,CCOC(=O)CCCOc1cc(C)c2nc(OCC)[nH]c2c1.CCOc1ccc(CBr)c(Cl)c1>>CCOC(=O)CCCOc1cc(C)c2nc(OCC)n(Cc3ccc(OCC)cc3Cl)c2c1,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US06121309,COc1ccc2ccc(C#N)cc2c1OS(=O)(=O)C(F)(F)F.OB(O)c1ccccc1>>COc1ccc2ccc(C#N)cc2c1-c1ccccc1,,CN(C)C=O,,CCN(CC)CC,[Cl-].[NH4+],test
US20140179676A1,CC1(C)OC(=O)CC(=O)O1.Cc1cc(Br)ccc1C=O>>Cc1cc(Br)ccc1C=C1C(=O)OC(C)(C)OC1=O,,C1COCCO1,O,,,test
US20140213581A1,COC(=O)c1ncc(Cl)nc1C.OCC(F)F>>COC(=O)c1ncc(OCC(F)F)nc1C,,O,,O=C([O-])[O-].[K+].[K+],,test
US20140296230A1,CI.CN1C(=O)Nc2ccc(Br)cc2C1c1ccccc1>>CN1C(=O)N(C)C(c2ccccc2)c2cc(Br)ccc21,,CN(C)C=O,,O,[H-].[Na+],test
US20090264650A1,Cc1ccc(C(N)=NO)cc1Cl.O=C(O)C1CC1>>Cc1ccc(-c2noc(C3CC3)n2)cc1Cl,,ClCCl,,O=C(n1ccnc1)n1ccnc1,,test
US20160096830A1,O=C(NCCCC[C@H](NC(=O)C1CCCOC1)C(=O)c1nc2ccccc2s1)OCc1ccccc1>>NCCCC[C@H](NC(=O)C1CCCOC1)C(=O)c1nc2ccccc2s1,,CC(=O)O,,Br,,test
US20130116243A1,CC1Oc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)cc2NC1=O.CI>>CC1Oc2nc(-c3ccc(C4(NC(=O)OC(C)(C)C)CCC4)cc3)c(-c3ccccc3)cc2N(C)C1=O,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US04532331,COC(CN)OC.COc1ccc(N=C=S)cc1>>COc1ccc(NC(=S)NCC(OC)OC)cc1,,ClC(Cl)Cl,,,,test
US20100130464A1,CC(C)(C)OC(=O)N1CCC(c2ccc(Cl)cc2)(c2ccc(Br)cc2)CC1.O=C=O>>CC(C)(C)OC(=O)N1CCC(c2ccc(Cl)cc2)(c2ccc(C(=O)O)cc2)CC1,,C1CCOC1,,[Li]CCCC,,test
US04305717,COc1ccc([N+](=O)[O-])cc1NCC(N)=O>>COc1ccc(N)cc1NCC(N)=O,[Fe],CC(=O)O,,O,,test
US20080200675A1,CCOC(=O)C(=O)c1c(F)cc(F)cc1F.ClC(Cl)(Cl)Cl>>CCOC(=O)C(=C(Cl)Cl)c1c(F)cc(F)cc1F,,CC#N,,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20050107449A1,N#Cc1ccc(Cl)nc1.OB(O)c1ccccc1F>>N#Cc1ccc(-c2ccccc2F)nc1,,Cc1ccccc1,O,O=C([O-])[O-].[Na+].[Na+],,test
US20110021522A1,COc1cccc2cc(C(=O)O)c(=O)oc12.N#Cc1ccccc1-c1cccc(N)c1>>COc1cccc2cc(C(=O)Nc3cccc(-c4ccccc4C#N)c3)c(=O)oc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20150119380A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.O=c1ccc2ccc(OS(=O)(=O)C(F)(F)F)cc2o1>>CC(C)(C)OC(=O)N1CC=C(c2ccc3ccc(=O)oc3c2)CC1,,CC#N,,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20060247250A1,Nc1cnc(Nc2ccc(S(=O)(=O)NCCN3CCCC3)cc2)nc1.O=C(Cl)c1c(Cl)cccc1Cl>>O=C(Nc1cnc(Nc2ccc(S(=O)(=O)NCCN3CCCC3)cc2)nc1)c1c(Cl)cccc1Cl,,C1CCOC1,,,,test
US20050014811A1,COC(=O)Nc1nc2ccc(OS(=O)(=O)c3ccc(NC4CCCC4)cc3)cc2[nH]1.NC1CC1>>O=C(Nc1nc2cc(OS(=O)(=O)c3ccc(NC4CCCC4)cc3)ccc2[nH]1)NC1CC1,,C1CCOC1,CN1CCCC1=O,C1CCC2=NCCCN2CC1,,test
US04652676,CC(=O)/C=C/C1=C(C)CCCC1(C)C.[NH4+]>>CC1=C(/C=C/C(C)N)C(C)(C)CC1,,CO,,[BH3-]C#N.[Na+],,test
US20060030595A1,COc1cccc(Br)n1.O=Cc1cccc(Br)n1>>COc1cccc(C(O)c2cccc(Br)n2)n1,,C1CCOC1,,[Li]CCCC,,test
US20110104765A1,COc1ccc(C[C@@](C)(C#N)N[C@@H](C(N)=O)c2ccccc2)cc1.O=S(=O)(O)O>>COc1ccc(C[C@](C)(N[C@@H](C(N)=O)c2ccccc2)C(N)=O)cc1,,ClCCl,,,,test
US20070270383A1,CC(C)(CCOP(=O)(OCc1ccccc1)OCc1ccccc1)C(=O)O.O=C(Cl)C(=O)Cl>>CC(C)(CCOP(=O)(OCc1ccccc1)OCc1ccccc1)C(=O)Cl,,ClCCl,,CN(C)C=O,,test
US20120252815A1,CC(=O)OCCCCCl.CC1(C)CCC(C)(C)c2cc(-c3cn(C4CCNCC4)nn3)ccc21>>CC1(C)CCC(C)(C)c2cc(-c3cn(C4CCN(CCCCO)CC4)nn3)ccc21,,CO,,Cl,[Na+].[OH-],test
US20070173519A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOc1ccc(N(C(=O)OC(C)(C)C)c2c(CCO[Si](C)(C)C(C)(C)C)c(NC3CCC(N)CC3)nc3ccnn23)cc1>>CCOc1ccc(N(C(=O)OC(C)(C)C)c2c(CCO[Si](C)(C)C(C)(C)C)c(NC3CCC(NC(=O)OC(C)(C)C)CC3)nc3ccnn23)cc1,,ClCCl,,CCN(CC)CC,[Cl-].[NH4+],test
US04327088,COCOc1ccc(C=O)cc1.COc1cc(O)c(C(C)=O)c(OC)c1>>COCOc1ccc(C=CC(=O)c2c(O)cc(OC)cc2OC)cc1,,CCO,,Cl,[Na+].[OH-],test
US05412102,CC(C)C(N)C(C)C.O=Cc1ccc(Br)cc1>>CC(C)C(N=Cc1ccc(Br)cc1)C(C)C,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,O,,test
US20130165436A1,O=C1COc2ccc(O)c(F)c2N1>>Oc1ccc2c(c1F)NCCO2,,C1CCOC1,,,,test
US20100093718A1,Brc1cccc(Nc2nncs2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC1(C)OB(c2cccc(Nc3nncs3)c2)OC1(C)C,,CS(C)=O,,CC(=O)[O-].[K+],,test
US20110275797A1,BrCCCCCBr.COC(=O)c1cc(N)ccc1OCc1ccccc1>>COC(=O)c1cc(N2CCCCC2)ccc1OCc1ccccc1,,CCOC(C)=O,O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140371199A1,C1COCCN1.O=C(O)c1ccc(Br)cc1N1CCOCC1>>O=C(c1ccc(Br)cc1N1CCOCC1)N1CCOCC1,,CCOC(C)=O,CN(C)C=O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20010014737A1,COC(=O)CC(=Cc1ccc(OC)cc1CN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC>>COC(=O)CC(Cc1ccc(OC)cc1CN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC,[Pd],CCOC(C)=O,,[H][H],,test
US05183820,Cc1c(CN2CCc3c(c4cccc(F)c4n3C)C2=O)ncn1C(=O)OCc1ccccc1>>Cc1[nH]cnc1CN1CCc2c(c3cccc(F)c3n2C)C1=O,,CCO,Cl,O,[Na+].[OH-],test
US20130090328A1,Cc1cc2nc(Cl)nc(Cl)c2s1.[OH-]>>Cc1cc2nc(Cl)[nH]c(=O)c2s1,,C1CCOC1,,Cl,,test
US20060135552A1,CC(=O)Nc1sc2ccccc2c1C(=O)c1ccccc1>>Nc1sc2ccccc2c1C(=O)c1ccccc1,,CCO,,[Na+].[OH-],,test
US20020198377A1,COC(=O)C(CCCC1CCCCC1)C(C)=O>>CC(=O)C(CCCC1CCCCC1)C(=O)O,,ClCCl,,[K+].[OH-],,test
US20110172278A1,CCN=C=S.COC(=O)c1ccc(N)cc1>>CCNC(=S)Nc1ccc(C(=O)OC)cc1,,CC#N,,O,,test
US20100216788A1,CC(C)(C)OC(=O)NCCn1ccc2ncnc(Cl)c21.Cc1cc(N)ccc1Oc1cccc(Cl)c1>>Cc1cc(Nc2ncnc3ccn(CCNC(=O)OC(C)(C)C)c23)ccc1Oc1cccc(Cl)c1,,CC(C)O,,O=C([O-])O.[Na+],,test
US20160075657A1,COc1ccc2c(c1)CCNC2.O=S(=O)(Cl)Cl>>COc1ccc2c(c1Cl)CCNC2,,CC(=O)O,,,,test
US20140045862A1,COc1ccc(CN(c2ccncn2)S(=O)(=O)c2cc(F)c(O[C@H]3CC(C)(C)C[C@@H]3c3ccnn3C)cc2F)c(OC)c1>>Cn1nccc1[C@H]1CC(C)(C)C[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20080200494A1,Cc1c(C2CC2)nc2ccc([N+](=O)[O-])cn12.Cl.O=C(O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1>>Cc1c(C2CC2)nc2ccc(NC(=O)c3ccc(-c4ccc(C(F)(F)F)cc4)cc3)cn12.Cl,,CCOC(C)=O,,,,test
US20070149508A1,CN(C)CCNC1CCN(C(=O)OC(C)(C)C)CC1.O=S(=O)(Cl)c1ccc(Br)cc1>>CN(C)CCN(C1CCN(C(=O)OC(C)(C)C)CC1)S(=O)(=O)c1ccc(Br)cc1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20100105711A1,CCOCC1(C)Nc2ccc(Br)cc2N1C(C)(C)C>>Cc1nc2ccc(Br)cc2n1C(C)(C)C,,O=C(O)C(F)(F)F,,,,test
US20040186077A1,CC(C)(C)OP(=O)(OC(C)(C)C)C(O)c1cccnc1>>O=P(O)(O)C(O)c1cccnc1,,CC(=O)O,O,,,test
US04370335,CC(=O)CCCCCCN1C(=O)c2ccccc2C1=O.OCCO>>CC1(CCCCCCN2C(=O)c3ccccc3C2=O)OCCO1,,c1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20130072523A1,C=C1C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1>>CC1C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1,O=[Pt]=O,CCO,,,,test
US20060276464A1,COC(=O)CCNS(=O)(=O)c1cc(S(=O)(=O)c2ccccc2)ccc1C>>Cc1ccc(S(=O)(=O)c2ccccc2)cc1S(=O)(=O)NCCC(=O)O,,C1CCOC1,O,[Li+].[OH-],,test
US20060148817A1,O=C(CBr)c1ccc(OCc2ccccc2)cc1OCc1ccccc1.O=C1CCC(=O)N1Br>>O=C(CBr)c1cc(Br)c(OCc2ccccc2)cc1OCc1ccccc1,,CN(C)C=O,,,,test
US20130287731A1,CCOC(=O)[C@@H]1CCC(C)C(=O)N1C(=O)OC(C)(C)C>>CCOC(=O)[C@@H]1CCC(C)CN1C(=O)OC(C)(C)C,,C1CCOC1,,CO,,test
US20050182025A1,C[Si](C)(C)CCCO.O=[N+]([O-])c1cc(Cl)c(O)cc1Cl>>C[Si](C)(C)CCCOc1cc(Cl)c([N+](=O)[O-])cc1Cl,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100056521A1,COC(=O)C(C#N)c1cc(C)c(OC)cc1[N+](=O)[O-]>>COc1cc([N+](=O)[O-])c(CC#N)cc1C,,CO,,Cl,,test
US20070060567A1,CC(C)(C)OC(=O)N1CCCc2ccc(C(=O)O)cc21.CCOC(=O)c1ccc(N)cc1>>CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)N(C(=O)OC(C)(C)C)CCC3)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20080287430A1,CC(=O)OC(C)=O.O=C(O)c1ccc(Cc2cc(Cl)ccc2O)o1>>CC(=O)Oc1ccc(Cl)cc1Cc1ccc(C(=O)O)o1,,c1ccncc1,,,,test
US20080300232A1,CC(C)(C)OC(=O)N1CCC(NC(=O)CCl)CC1.Oc1cccnc1>>CC(C)(C)OC(=O)N1CCC(NC(=O)COc2cccnc2)CC1,,C1CCOC1,,CC(C)(C)[O-].[K+],,test
US20160237095A1,Cc1cc(Cl)nc(Cl)n1.Nc1ccc2[nH]ncc2c1>>Cc1cc(Nc2ccc3[nH]ncc3c2)nc(Cl)n1,,CCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20070232583A1,CC(C)(C)NS(=O)(=O)c1cccc(-c2cn(-c3nc(-c4ccc(Cl)cc4)cc(C(F)(F)F)n3)cn2)c1>>NS(=O)(=O)c1cccc(-c2cn(-c3nc(-c4ccc(Cl)cc4)cc(C(F)(F)F)n3)cn2)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090253705A1,C#CCC[C@@H](C(=O)N1C(=O)OCC1c1ccccc1)[C@H](O)c1ccccc1.OO>>C#CCC[C@@H](C(=O)O)[C@H](O)c1ccccc1,,O,,C1CCOC1,[Li+].[OH-],test
US20100029650A1,CC(Oc1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1)C1CCN(c2ncc(F)cn2)CC1>>C[C@H](Oc1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1)C1CCN(c2ncc(F)cn2)CC1,,CO,,O=C=O,,test
US20030065179A1,Cl.Cn1c2c(c(=O)n1-c1cnc3ccccc3n1)CN(C(=O)OC(C)(C)C)CC2>>Cl.Cn1c2c(c(=O)n1-c1cnc3ccccc3n1)CNCC2,,CO,,,,test
US20130197059A1,CC(C)(C)OC(=O)NCCCOc1cc(O)cc(C(=O)ON2C(=O)CCC2=O)c1.COC(=O)[C@H](CN)NC(=O)c1c(C)nc(NCCCc2cccc(O)c2)nc1C>>COC(=O)[C@H](CNC(=O)c1cc(O)cc(OCCCNC(=O)OC(C)(C)C)c1)NC(=O)c1c(C)nc(NCCCc2cccc(O)c2)nc1C,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,Cl,test
US20120040949A1,CCS(=O)(=O)c1ccc(Nc2cc(-c3cccc(-n4ncc5cc(C(C)(C)C)cc(F)c5c4=O)c3COC(C)=O)nn(C)c2=O)nc1>>CCS(=O)(=O)c1ccc(Nc2cc(-c3cccc(-n4ncc5cc(C(C)(C)C)cc(F)c5c4=O)c3CO)nn(C)c2=O)nc1,,C1COCCO1,,[Li+].[OH-],,test
US20130035446A1,O=C(/C=C/c1ccc(C(F)(F)Oc2ccc(OCCCC(F)(F)F)cc2)cc1)OCc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1>>Nc1cc(N)cc(COC(=O)/C=C/c2ccc(C(F)(F)Oc3ccc(OCCCC(F)(F)F)cc3)cc2)c1,[Zn],CN(C)C=O,O,,,test
US04737514,N#Cc1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O.NCCN>>O=C1c2ccccc2S(=O)(=O)c2cc(C3=NCCN3)ccc21,,CO,,C[O-].[Na+],,test
US20110015238A1,CCCCC(C)(C)[C@H](O)/C=C/[C@H]1COC(=O)N1CCSc1nc(C(=O)OCC)cs1.C[C@]1(CCCC(F)(F)F)CC=C[C@H]2COC(=O)N2CCSc2nc(cs2)C(=O)O1>>C[C@@](O)(C/C=C/[C@H]1COC(=O)N1CCSc1nc(C(=O)O)cs1)CCCC(F)(F)F,,CO,,C1CCOC1,,test
US08802665B2,CC1CCCNC1.CCOC1(O[Si](C)(C)C)CC1.C[Si](C)(C)C#N>>CC1CCCN(C2(C#N)CC2)C1,,CCOC(C)=O,,CCCCCCC,,test
US20050176859A1,C1CCNCC1.CC(C)(C)c1cccc(C(C)(C)C)c1O.O=Cc1ccccc1>>CC(C)(C)c1cc(C(c2ccccc2)N2CCCCC2)cc(C(C)(C)C)c1O,,CCO,,,,test
US06610705B1,COc1ccc(C(c2ccc(O)cc2)C2CCCc3ccccc32)cc1.Cl.ClCCN1CCCC1>>COc1ccc(C(c2ccc(OCCN3CCCC3)cc2)C2CCCc3ccccc32)cc1.Cl,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US05665718,CCCNCCC.O=C1c2c(Cl)cccc2-n2cnc(-c3noc(CCl)n3)c2[C@@H]2CCCN12>>CCCN(CCC)Cc1nc(-c2ncn3c2[C@@H]2CCCN2C(=O)c2c(Cl)cccc2-3)no1,,CN(C)C=O,,,,test
US05670499,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NCC(N)Cc1c[nH]c2ccccc12>>CC(C)(C)OC(=O)NCC(N)Cc1c[nH]c2ccccc12,,C1CCOC1,,,,test
US20110245221A1,CC(=O)Cl.CCNC(=O)c1noc(-c2cc(Cl)c(OCc3ccccc3)cc2OCc2ccccc2)c1N>>CCNC(=O)c1noc(-c2cc(Cl)c(OCc3ccccc3)cc2OCc2ccccc2)c1NC(C)=O,,ClCCl,,,,test
US20100130495A1,CC(=O)N1CCc2nc(Nc3ccc(-c4cnco4)cc3)nc(O)c2C1.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(=O)N1CCc2nc(Nc3ccc(-c4cnco4)cc3)nc(OS(=O)(=O)C(F)(F)F)c2C1,CN(C)c1ccncc1,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20040087552A1,CCOC(=O)C1CCN(Cc2ccccc2)CC1.O=C1CCCCC1>>O=C1CCCCC1C(=O)C1CCN(Cc2ccccc2)CC1,,C1CCOC1,CCN(CC)CC,CCOC(C)=O,[H-].[Na+],test
US20130150339A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(-c4ccc(C(F)(F)F)cc4Br)nccc3c2)c(OC)c1>>COc1ccc(CN(c2nccs2)S(=O)(=O)c2ccc3c(-c4ccc(C(F)(F)F)cc4C4=CCN(C(=O)OC(C)(C)C)CC4)nccc3c2)c(OC)c1,,O,,C1COCCO1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20100120810A1,COc1cc2cc(OS(=O)(=O)C(F)(F)F)nc(C)c2cc1OC.OB(O)c1ccc(Cl)cc1>>COc1cc2cc(-c3ccc(Cl)cc3)nc(C)c2cc1OC,,Cc1ccccc1,,CCOC(C)=O,O=C([O-])[O-].[Na+].[Na+],test
US20040110807A1,CCO[C@H](C(=O)N1C(=O)OC[C@@H]1Cc1ccccc1)[C@H](O)c1c(C)cc(OCc2ccccc2)cc1C.CO>>CCO[C@H](C(=O)OC)[C@H](O)c1c(C)cc(OCc2ccccc2)cc1C,,CO,,C[O-].[Na+],,test
US04988699,COC(=O)C1CC=C(O[Si](C)(C)C)CC1.NC(N)=S>>COC(=O)C1CCc2nc(N)sc2C1,,C1CCOC1,,O=C1CCC(=O)N1Br,,test
US05191092,COc1c(C(=O)CCC(=O)O)ccc2ccccc12>>COc1c(CCCC(=O)O)ccc2c1CCCC2,[Pd],CCO,,[H][H],,test
US05010196,C=O.CC(C)NCCCN>>CC(C)N1CCCNC1,,CC(C)O,,,,test
US05324743,CCCc1c(O)cccc1O.COC(=O)c1ccccc1CBr>>CCCc1c(O)cccc1OCc1ccccc1C(=O)OC,,CCOC(C)=O,CN(C)C=O,CCCCCC,[H-].[Na+],test
US20060094778A1,CCC(CC)(c1ccc(OCC(O)C(C)(C)C)c(C)c1)c1ccc(C(=O)N(C)OC)c(C)c1>>CCC(CC)(c1ccc(C=O)c(C)c1)c1ccc(OCC(O)C(C)(C)C)c(C)c1,,CCOCC,,C1CCOC1,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20150038528A1,CC(C)(C)OC(=O)C(CN)C1CC1.COC(=O)c1nc(C#N)c2cc(Oc3ccccc3F)ccc2c1O>>CC(C)(C)OC(=O)C(CNC(=O)c1ncc2c(c1O)=CCC(C#N)(Oc1ccccc1F)C=2)C1CC1,,CC(=O)N(C)C,,C1CCC2=NCCCN2CC1,,test
US20080153836A1,COC(=O)c1cc(-c2ccoc2)c(C(F)(F)F)cc1N>>COC(=O)c1cc(C2CCOC2)c(C(F)(F)F)cc1N,[Ni],C1CCOC1,O,,,test
US20060134198A1,COCCOCCOC.Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1>>COCCOCCOC.Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1,,CCOCC,,,,test
US20050026964A1,CC(C)(C)OC(=O)CBr.CCOC(=O)c1c[nH]c(=O)cc1Nc1ccc(I)cc1F>>CCOC(=O)c1cn(CC(=O)OC(C)(C)C)c(=O)cc1Nc1ccc(I)cc1F,,CN(C)C=O,,[H-].[Na+],,test
US20140378686A1,CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(F)cc(F)c3C[C@H]2O)C1.COC(=O)Cl>>COC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2[C@@H]2c3cc(F)cc(F)c3C[C@H]2O)C1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20040063693A1,CC(C)(C)OC(=O)N1CCN(c2nccnc2OCCO)CC1.N#Cc1ccc(O)cc1>>CC(C)(C)OC(=O)N1CCN(c2nccn(CCOc3ccc(C#N)cc3)c2=O)CC1,,ClCCl,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20140296066A1,CC#N.Clc1cc(Br)cnc1Cl>>N#CCc1ncc(Br)cc1Cl,,C1CCOC1,,O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US07569686B1,CN1CC2(CO)OC(n3ccc(=O)[nH]c3=O)C(O1)C2O.COc1ccc(C(Cl)(c2ccccc2)c2ccc(OC)cc2)cc1>>COc1ccc(C(OC(c2ccccc2)C23CN(C)OC(C(n4ccc(=O)[nH]c4=O)O2)C3O)c2ccc(OC)cc2)cc1,,c1ccncc1,,,,test
US20060142202A1,CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)NC(=O)CCCCCN.O=C(CCSSc1ccccn1)ON1C(=O)CCC1=O>>CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)NC(=O)CCCCCNC(=O)CCSSc1ccccn1,,C1CCOC1,CN(C)C=O,CCN(CC)CC,Cl,test
US20160166560A1,CN(C(=O)n1cnc(-c2ccc(OS(N)(=O)=O)cc2)c1)C1CCN(c2ccc(O)cc2)CC1.Cl>>CN(C(=O)n1cnc(-c2ccc(OS(N)(=O)=O)cc2)c1)C1CCN(c2ccc(O)cc2)CC1.Cl,,CCOC(C)=O,,CCOCC,,test
US20160075713A1,Clc1ncnc2[nH]ccc12.NC1CCN(CC(F)(F)c2ccccn2)CC1>>FC(F)(CN1CCC(Nc2ncnc3[nH]ccc23)CC1)c1ccccn1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20160009720A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Cn1c(=O)oc2cc(Br)ccc21>>Cn1c(=O)oc2cc(B3OC(C)(C)C(C)(C)O3)ccc21,,C1COCCO1,,ClCCl,CC(=O)[O-].[K+],test
US20130184248A1,Fc1ccc(-c2n[nH]c(-c3ccc(F)cc3)n2)cc1.O=C(CBr)N1CCN(c2ncccn2)CC1>>O=C(Cn1nc(-c2ccc(F)cc2)nc1-c1ccc(F)cc1)N1CCN(c2ncccn2)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20030100770A1,CC(C)(C)OC(=O)[C@H]1CCCN1C(=O)COc1cc(OCC(=O)N2CCC[C@@H]2C(=O)OC(C)(C)C)cc(OCC(=O)N2CCC[C@@H]2C(=O)OC(C)(C)C)c1>>O=C(O)[C@H]1CCCN1C(=O)COc1cc(OCC(=O)N2CCC[C@@H]2C(=O)O)cc(OCC(=O)N2CCC[C@@H]2C(=O)O)c1,,O=C(O)C(F)(F)F,,,,test
US20030004148A1,CC(C)CCC[C@@H](C)[C@H]1CC=C2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](O)C[C@@H]1CC3.O=C(Cl)c1ccncc1>>CC(C)CCC[C@@H](C)[C@H]1CC=C2C3=C(CC[C@@]21C)[C@@]1(C)CC[C@H](C(=O)c2ccncc2)C[C@@H]1CC3,,c1ccncc1,,Cl,,test
US20160145245A1,CN(C(=O)Cc1ccccn1)[C@H](CN1CCCC1)c1cccc([N+](=O)[O-])c1>>CN(C(=O)Cc1ccccn1)[C@H](CN1CCCC1)c1cccc(N)c1,[Ni],CCO,,NN,O,test
US20140256705A1,COCc1cc2c(-c3ccccc3Oc3ccccc3)n(COCC[Si](C)(C)C)c(C)c2c(OC)n1>>COCc1cc2c(-c3ccccc3Oc3ccccc3)n(COCC[Si](C)(C)C)c(C)c2c(=O)[nH]1,,c1ccncc1,,[I-].[Li+],,test
US04419357,COc1cccc(C(=O)O)c1[N+](=O)[O-].ClP(Cl)(Cl)(Cl)Cl>>COc1cccc(C(=O)Cl)c1[N+](=O)[O-],,ClCCl,,Cc1ccccc1,,test
US04273932,CCOC(=O)c1cnc2c(c1O)C(=NO)CCC2>>CCOC(=O)c1cnc2c(c1O)C(N)CCC2,[Zn],CC(=O)O,,,,test
US20080319033A1,Cc1csc(N)n1.N=C(c1ccccc1)c1ccccc1>>Cc1csc(N=C(c2ccccc2)c2ccccc2)n1,,Cc1ccccc1,,,,test
US20140179668A1,COC(=O)[C@@H]1CCCN1c1nc2c(c(Nc3cc(C(C)C)[nH]n3)n1)CCC2.Nc1nccs1>>CC(C)c1cc(Nc2nc(N3CCC[C@H]3C(=O)Nc3nccs3)nc3c2CCC3)n[nH]1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US06486153B1,CC(C)(C)OC(=O)n1c(Br)c(CCOC2CCCCO2)c2ccccc21>>Brc1[nH]c2ccccc2c1CCOC1CCCCO1,,CO,,C[O-].[Na+],,test
US20110065727A1,CC(C)(C)[Si](C)(C)OCc1ccccc1-c1ccc2nc(-c3ccoc3)cn2c1>>OCc1ccccc1-c1ccc2nc(-c3ccoc3)cn2c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20040067955A1,CC(C)n1nc(-c2cc(C#N)c(N)nc2-c2ccccc2)ccc1=O.CC(N)=S>>CC(C)n1nc(-c2cc(C(N)=S)c(N)nc2-c2ccccc2)ccc1=O,,C1COCCO1,CN(C)C=O,Cl,[Na+].[OH-],test
US20100093730A1,CCOC(=O)C(CC#N)(c1ccc(F)cc1)c1ccc(F)cc1>>O=C1NCCC1(c1ccc(F)cc1)c1ccc(F)cc1,O=[Pt]=O,CC(=O)O,,,,test
US20150232501A1,CC[C@H](C)OC(=O)[C@@H](C)N.Cl.O=P(Cl)(Cl)Oc1ccccc1.Oc1c(F)c(F)c(F)c(F)c1F>>CC[C@@H](C)OC(=O)[C@H](C)NP(=O)(Oc1ccc(Cl)cc1)Oc1c(F)c(F)c(F)c(F)c1F,,ClCCl,,CCN(CC)CC,,test
US20110065708A1,CC(=O)c1ccc2nnc(C(C)c3c(F)cc4ncccc4c3F)n2n1.NOCCO>>C/C(=N\OCCO)c1ccc2nnc(C(C)c3c(F)cc4ncccc4c3F)n2n1,,CO,,Cl,[Na+].[OH-],test
US20080070920A1,COc1ccc(CNc2cc(F)cc(CBr)c2)cc1.Cc1cc(C#N)cc(C(=O)c2[nH]c(=O)[nH]c(=O)c2C(C)C)c1>>COc1ccc(CNc2cc(F)cc(Cn3c(C(=O)c4cc(C)cc(C#N)c4)c(C(C)C)c(=O)[nH]c3=O)c2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20030216417A1,COc1cc2c(Cl)ncnc2cc1OCC1CCCN(C)C1.Cc1ccc(NC(=O)c2ccnc(N3CCOCC3)c2)cc1N>>COc1cc2c(Nc3cc(NC(=O)c4ccnc(N5CCOCC5)c4)ccc3C)ncnc2cc1OCC1CCCN(C)C1,,CCOCC,,Cl,,test
US20060128765A1,COC(=O)c1c(F)cccc1-c1ccc(CN)c(F)c1.O=C1CCCO1>>COC(=O)c1c(F)cccc1-c1ccc(CNC(=O)CCCO)c(F)c1,,CO,,CCN(CC)CC,Cl,test
US20070099955A1,COc1c(C)ccc2c1CC(C1CCN(CCC(C)NC(=O)c3ccc(Cl)cc3)CC1)OC2CNC=O>>COc1c(C)ccc2c1C[C@@H](C1CCN(CCC(C)NC(=O)c3ccc(Cl)cc3)CC1)O[C@H]2CN,,C1CCOC1,CO,[Na+].[OH-],,test
US20140288123A1,CC(C)CC(O)c1ccc(Br)cc1.Oc1ccccc1>>CC(C)CC(Oc1ccccc1)c1ccc(Br)cc1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120117667A1,CCCC(=O)C(=O)O.Nc1ncc(-c2ccc(O)cc2)nc1Cc1ccccc1>>CCCC(Nc1ncc(-c2ccc(O)cc2)nc1Cc1ccccc1)C(=O)O,[Pd],CCO,,,,test
US06291455B1,COC(=O)Oc1ccc(F)c(N)c1>>Nc1cc(O)ccc1F,,CO,,N,,test
US20090291983A1,CCOC(=O)c1ccccc1C(Br)C(=O)OCC.COc1cc(F)ccc1CN>>CCOC(=O)C1c2ccccc2C(=O)N1Cc1ccc(F)cc1OC,,CC#N,CCOC(C)=O,CCN(CC)CC,,test
US20090048320A1,C[Si](C)(C)C#Cc1cccc(Br)c1>>C#Cc1cccc(Br)c1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20090098218A1,CCOC(=O)CC(=O)NC1(C2(C(=O)OCC)CC2)CC1>>COC(=O)C1C(=O)NC2(CC2)C2(CC2)C1=O,,CO,Cc1ccccc1,[Na],,test
US20040235822A1,CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(SCc4cccnc4)cc2)CCN3CC(C)C)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(S(=O)Cc4cccnc4)cc2)CCN3CC(C)C)cc1,,ClCCl,,O=S([O-])([O-])=S.[Na+].[Na+],,test
US05036078,CN1CC=C(c2c[nH]c3ccc(CCNS(C)(=O)=O)cc23)CC1>>CN1CCC(c2c[nH]c3ccc(CCNS(C)(=O)=O)cc23)CC1,[Pd],Cl,,,,test
US20060270637A1,CCCC(=O)OCC1CC(c2ccc(Br)cn2)=NO1>>OC[C@H]1CC(c2ccc(Br)cn2)=NO1,,CO,,,,test
US20110118245A1,CC(C)(C)c1cc(NC(=O)Oc2ccccc2)n(-c2ccccc2)n1.Nc1cc(O)ccc1F>>CC(C)(C)c1cc(NC(=O)Nc2cc(O)ccc2F)n(-c2ccccc2)n1,,CC#N,,C1CCC2=NCCCN2CC1,,test
US05576340,CC(C)(C)[Si](C)(C)Cl.CCOC(=O)[C@@H](O)c1ccccc1>>CCOC(=O)[C@@H](O[Si](C)(C)C(C)(C)C)c1ccccc1,,CN(C)C=O,,c1c[nH]cn1,,test
US05831072,CC(C)(C)OC(=O)c1ncn([C@@H]2O[C@H](COC(=O)c3ccccc3)[C@@H](OC(=O)c3ccccc3)[C@@H]2F)c1N1C(=O)c2ccccc2C1=O>>O=C(OC[C@H]1O[C@@H](n2cnc(C(=O)O)c2N2C(=O)c3ccccc3C2=O)[C@@H](F)[C@@H]1OC(=O)c1ccccc1)c1ccccc1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20110092698A1,C[C@H]1C(=O)N(CCC(=O)OC(C)(C)C)CCN1C(=O)Nc1ccc(Cl)c(Cl)c1>>C[C@H]1C(=O)N(CCC(=O)O)CCN1C(=O)Nc1ccc(Cl)c(Cl)c1,,ClCCl,,Cl,,test
US20110028493A1,CCOC(=O)c1cnn(CC(N)=S)c1.O=C(CBr)c1ccc(Cl)cc1>>CCOC(=O)c1cnn(Cc2nc(-c3ccc(Cl)cc3)cs2)c1,,CCO,,,,test
US20110275611A1,Cc1nc(C2CNCCO2)[nH]c1-c1ccccc1.Nc1nc(Cl)cc(Cl)n1>>Cc1nc(C2CN(c3cc(Cl)nc(N)n3)CCO2)[nH]c1-c1ccccc1,,CCO,,CCN(C(C)C)C(C)C,,test
US07074819B2,CC(C)(C)[Si](C)(C)OCCOCCO.CCCCCC>>C#CCOCCOCCO[Si](C)(C)C(C)(C)C,,C1CCOC1,CCOC(C)=O,O,[H-].[Na+],test
US20150112074A1,CCN(C(=O)CCCl)c1cn(-c2cccnc2)nc1Cl.FC(F)(F)CCS>>CCN(C(=O)CCSCCC(F)(F)F)c1cn(-c2cccnc2)nc1Cl,,CCOC(C)=O,O,CO,[K+].[OH-],test
US20070032525A1,COC(=O)c1cccc2[nH]c(NCC3CCN(C(=O)OC(C)(C)C)CC3)nc12>>CC(C)(C)OC(=O)N1CCC(C=Nc2nc3c(C(=O)O)cccc3[nH]2)CC1,,CO,,Cl,[Li+].[OH-],test
US20090221555A1,COC(=O)c1scc(C)c1N>>Cc1csc(C(=O)O)c1N,,O,,CO,[Na+].[OH-],test
US20040077669A1,Fc1ccccc1-c1cc(Cl)ncn1.OCC#CCO>>OCC#CCOc1cc(-c2ccccc2F)ncn1,,CN(C)C=O,,O,[H-].[Na+],test
US20120115868A1,CC(C)N.Cc1nc(/C=C/c2c(-c3ccc(F)cc3)nnn2C)sc1C(=O)O>>Cc1nc(/C=C/c2c(-c3ccc(F)cc3)nnn2C)sc1C(=O)NC(C)C,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20160002263A1,Cc1nc2cc3nn2c(c1[C@H](OC(C)(C)C)C(=O)O)N1CCC(C)(CC1)OCC=CCCOc1ccccc1Cc1cnc-3s1>>Cc1nc2cc3nn2c(c1[C@H](OC(C)(C)C)C(=O)O)N1CCC(C)(CC1)OCCCCCOc1ccccc1Cc1cnc-3s1,[Pd],CO,,[H][H],,test
US20100105667A1,COc1cc(OC)c(Cl)c(-c2ccc(C(=O)O)c3ncc(N(C)CCN(C)C)nc23)c1Cl.Nc1ccccn1>>COc1cc(OC)c(Cl)c(-c2ccc(C(=O)Nc3ccccn3)c3ncc(N(C)CCN(C)C)nc23)c1Cl,,CO,ClCCl,,,test
US20110224204A1,COc1cccc([N+](=O)[O-])c1Br>>O=[N+]([O-])c1cccc(O)c1Br,,ClCCl,,BrB(Br)Br,,test
US20090247567A1,N#Cc1ccc2c(n1)-c1sc(-c3ncnn3-c3ccc(F)cc3F)cc1CCO2.OO>>NC(=O)c1ccc2c(n1)-c1sc(-c3ncnn3-c3ccc(F)cc3F)cc1CCO2,,CS(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20140235657A1,CCCN.COc1cc2ncnc(Oc3ccc4c(cc(C)n4C(=O)Oc4ccc([N+](=O)[O-])cc4)c3F)c2cc1OC>>CCCNC(=O)n1c(C)cc2c(F)c(Oc3ncnc4cc(OC)c(OC)cc34)ccc21,,CN(C)C=O,,,,test
US20110021520A1,CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc([N+](=O)[O-])ccc2F)CO[C@@]1(C)C(F)(F)F>>CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(N)ccc2F)CO[C@@]1(C)C(F)(F)F,[Pd],C1CCOC1,CC(C)O,,,test
US20030100576A1,CCOC(=O)C(Br)c1cccnc1.Oc1ccccn1>>CCOC(=O)C(Oc1ccccn1)c1cccnc1,,CN(C)C=O,,[H-].[Na+],,test
US20100167934A1,N#Cc1cnc(Cl)nc1N.N[C@@H]1CCCc2ccccc21>>N#Cc1cnc(N[C@@H]2CCCc3ccccc32)nc1N,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050171130A1,CC(CO)(C(F)(F)F)C(F)(F)F.Clc1cc(Cl)ncn1>>CC(COc1cc(Cl)ncn1)(C(F)(F)F)C(F)(F)F,,C1CCOC1,,[H-].[Na+],[Cl-].[NH4+],test
US20110070161A1,BrBr.CCOC(=O)C1CCCCC1=O>>CCOC(=O)C1=C(O)C(Br)CCC1,,CCOCC,,,,test
US20060135578A1,CCc1nc(/C=C/c2cn(-c3ccccc3)nc2O)cs1.COc1cc(CCl)ccc1OCc1nc(-c2cccc(C#N)c2)oc1C>>CCc1nc(/C=C/c2cn(-c3ccccc3)nc2OCc2ccc(OCc3nc(-c4cccc(C#N)c4)oc3C)c(OC)c2)cs1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20140288088A1,CC(C)(C)OC(=O)N1CCN(c2cc3ccc(C#N)cc3cn2)C(=O)C1.Cl>>Cl.N#Cc1ccc2cc(N3CCNCC3=O)ncc2c1,,C1COCCO1,,,,test
US20080004323A1,C[Si](C)(C)C#CC(=Nc1ccccc1)SCC1CC1.Fc1ccc(S)cc1>>Fc1ccc(SC=CC(=Nc2ccccc2)SCC2CC2)cc1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20030220345A1,CC(=O)OC(C)=O.CCn1c(=N)c(-c2cc(OC)cc(OC)c2)cc2cnc(SC)nc21>>CCn1c(=NC(C)=O)c(-c2cc(OC)cc(OC)c2)cc2cnc(SC)nc21,,COC(C)(C)C,,,,test
US20050203160A1,Cn1nc(-c2ccc(C(F)(F)F)cc2)c(Br)c1C(C)(C)O[SiH2]C(C)(C)C>>Cn1nc(-c2ccc(C(F)(F)F)cc2)c(Br)c1CO,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20110190490A1,Nc1c(O)nc(Cc2ccc(Cl)cc2)nc1O.S=C(Cl)Cl>>Oc1nc(Cc2ccc(Cl)cc2)nc2oc(S)nc12,,CN1CCCC1=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150291626A1,CCOC(CCc1ccc2ccc(C)cc2n1)OCC>>Cc1ccc2ccc(CCC=O)nc2c1,,O,O=C(O)C(F)(F)F,,,test
US04719200,C[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O>>C[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O,,O,,,,test
US20090062518A1,CC(C)(C)C(=O)OC[C@H]1O[C@@H](Br)[C@H](OC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@@H]1OC(=O)C(C)(C)C.CCC(=O)n1[nH]c(=O)c(Cc2ccccc2)c1C(C)C>>CCC(=O)n1nc(O[C@@H]2O[C@H](COC(=O)C(C)(C)C)[C@@H](OC(=O)C(C)(C)C)[C@H](OC(=O)C(C)(C)C)[C@H]2OC(=O)C(C)(C)C)c(Cc2ccccc2)c1C(C)C,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20040116518A1,O=C(/C=C/c1ccc(Sc2ccc(Cl)cc2Cl)c([N+](=O)[O-])c1)NCCCN1CCCC1=O>>Nc1cc(/C=C/C(=O)NCCCN2CCCC2=O)ccc1Sc1ccc(Cl)cc1Cl,,CCO,,Cl[Sn]Cl,,test
US20100074083A1,CC1(C)CC(=O)CC(C)(C)N1.CCCCCCCCCCCCN>>CCCCCCCCCCCCNC1CC(C)(C)NC(C)(C)C1,O=[Pt],CO,,,,test
US20130059834A1,CN(C)CCCn1nc(-c2cnc3c(n2)c(C(=O)NC(C)(C)C)cn3COCC[Si](C)(C)C)c2cc(OC(F)F)ccc21>>CN(C)CCCn1nc(-c2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)c2cc(OC(F)F)ccc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130338159A1,CS(=O)c1nccc(-c2cnc(N)nc2CC2CC2)n1.NC1CCCOC1>>Nc1ncc(-c2ccnc(NC3CCCOC3)n2)c(CC2CC2)n1,,CS(C)=O,,CCN(CC)CC,Cl,test
US20130059834A1,COC(=O)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)c2ncc(-c3nn(C)c4ccc(OCCCC(C)(C)N)cc34)nc12>>Cn1nc(-c2cnc3c(n2)c(C(=O)O)cn3C(c2ccccc2)(c2ccccc2)c2ccccc2)c2cc(OCCCC(C)(C)N)ccc21,,C1COCCO1,O,[K+].[OH-],,test
US20090163512A1,C=C(N=Cc1cc(F)ccc1C)O[Si](C)(C)C.CS(=O)COc1ccc(Cl)cc1/C=C1\C(=O)N(C(=O)OC(C)(C)C)c2cc(Cl)ccc21>>Cc1ccc(F)cc1C1NC(=O)CC(c2cc(Cl)ccc2OCS(C)=O)C12C(=O)Nc1cc(Cl)ccc12,,Cc1ccccc1,,,,test
US20100168075A1,CC(C)(C)OC(=O)NCC=O.CC(C)[C@@H](N)C(=O)OC(C)(C)C>>CC(C)[C@@H](NCCNC(=O)OC(C)(C)C)C(=O)OC(C)(C)C,,CO,,[BH4-].[Na+],,test
US20090253656A1,COc1ccc(/C(C#N)=C/c2ccc(N3CCC(OC(=O)CN(C)C)CC3)s2)cc1OC.Cl>>COc1ccc(/C(C#N)=C/c2ccc(N3CCC(OC(=O)CN(C)C)CC3)s2)cc1OC.Cl,,CCO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20150232420A1,C=CC(=O)Cl.COC(=O)[C@H](Cc1ccc(N)cc1)NC(=O)OCc1ccccc1>>C=CC(=O)Nc1ccc(C[C@H](NCOCc2ccccc2)C(=O)OC)cc1,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US04032525,CSc1ccc2c(c1)C(=O)Cc1ccc(C)cc1O2.Cl>>CSc1ccc2c(c1)C(Cl)Cc1ccc(C)cc1O2,,c1ccccc1,,[Ca+2].[Cl-].[Cl-],,test
US04806685,CNCCOc1ccc(C(=C(c2ccccc2)C(F)(F)F)c2ccc(OCOC)cc2)cc1.Cl>>CNCCOc1ccc(C(=C(c2ccccc2)C(F)(F)F)c2ccc(O)cc2)cc1.Cl,,CO,,,,test
US20040208823A1,COC(=O)[C@H](CNC(=O)c1ccc2c(CCCNc3ccccn3)nn(C)c2c1)NS(=O)(=O)c1c(C)cc(OCCCC(=O)NCCNC(=O)OCc2ccccc2)cc1C>>COC(=O)[C@H](CNC(=O)c1ccc2c(CCCNC3=NCCCC3)nn(C)c2c1)NS(=O)(=O)c1c(C)cc(OCCCC(=O)NCCN)cc1C,[Pd],CO,,O=C(O)C(F)(F)F,,test
US20090298836A1,CCOC(=O)c1ccc2[nH]c(=O)oc2c1>>O=C(O)c1ccc2[nH]c(=O)oc2c1,,C1CCOC1,,[Li+].[OH-],,test
US20050176905A1,C=CC(Cl)c1ccccc1.CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21>>C=Cc1ccc(CN2CCN(c3cc4c(cc3F)c(=O)c(C(=O)O)cn4CC)CC2)cc1,,O,,CCN(CC)CC,,test
US20070072873A1,COC(=O)c1cscc1NC(=O)CCCCc1ccccc1>>O=C(CCCCc1ccccc1)Nc1cscc1C(=O)O,,C1CCOC1,CO,Cl,[Li+].[OH-],test
US20120208827A1,Brc1ccc2occc2c1.O=Cc1ccc(B(O)O)cc1>>O=Cc1ccc(-c2ccc3occc3c2)cc1,,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20140256733A1,Cc1ccc(S(=O)(=O)Cl)cc1.O=C1CN=Cc2ccsc21>>Cc1ccc(S(=O)(=O)Oc2cncc3ccsc23)cc1,,C1CCOC1,,[H-].[Na+],,test
US20040254319A1,O=S(=O)(F)C(F)(C(F)(F)F)C(F)(F)C(F)(Cl)C(F)(F)Cl>>O=S(=O)(F)C(F)(C(F)(F)F)C(F)(F)C(F)=C(F)F,[Zn],CN(C)C=O,,,,test
US20090215843A1,COc1ccc(CCc2ccc(F)cc2CO)cc1.[Br-].c1ccc([PH+](c2ccccc2)c2ccccc2)cc1>>COc1ccc(CCc2ccc(F)cc2C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.[Br-],,CC#N,,,,test
US20090099140A1,CC(C)(O)CCC[C@@](C)(CC=O)[C@H]1CC[C@H]2[C@@H](O[Si](C)(C)C(C)(C)C)CCC[C@@]21C.CO[PH](=O)OC>>C#CC[C@](C)(CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H](O[Si](C)(C)C(C)(C)C)CCC[C@@]21C,,CO,,O,O=C([O-])[O-].[K+].[K+],test
US20040006114A1,CCS(=O)(=O)Cl.NCc1cccnc1>>CCS(=O)(=O)NCc1cccnc1,,ClCCl,,CCOCC,,test
US04929622,BrCC1CC1.CC1C2CC3=C(CCC4=C3C=CNC=CC41C)N2>>CC1C2CC3=C(CCC4=C3C=CNC=CC41C)N2CC1CC1,,CCOC(C)=O,O,CCN(C(C)C)C(C)C,CN(C)C=O,test
US20110172442A1,COC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C=Cc1cccc(OC(C)=O)c1>>COc1ccc(C[C@H](NC(=O)C=Cc2cccc(O)c2)C(=O)O)cc1,,CO,,[Na+].[OH-],,test
US20020037856A1,CCCn1cc([N+](=O)[O-])cc1C(=O)NCCC(=N)N>>CCCn1cc(N)cc1C(=O)NCCC(=N)N,[Pd],CO,,[H][H],,test
US20080039444A1,Cc1ccc(S(=O)(=O)OCCNC(=O)OC(C)(C)C)cc1.O=c1c2ccccc2c(Cc2ccc(Cl)cc2)nn1C1CCCNCC1>>CC(C)(C)OC(=O)NCCN1CCCC(n2nc(Cc3ccc(Cl)cc3)c3ccccc3c2=O)CC1,,CC(C)=O,,CCN(C(C)C)C(C)C,[I-].[Na+],test
US20090220420A1,CC(=O)NNc1ccccc1.CC(O)Br>>CC(=O)NN(CCO)c1ccccc1,,Cc1ccccc1,,CCN(C(C)C)C(C)C,,test
US04997840,O=C(CBr)c1ccccc1[N+](=O)[O-].O=C(O)c1ccccc1>>O=C(OCC(=O)c1ccccc1[N+](=O)[O-])c1ccccc1,,O,,O=C([O-])[O-].[K+].[K+],,test
US05866568,COc1nc(C)cnc1N(COCC[Si](C)(C)C)S(=O)(=O)c1cccnc1-c1ccc(SC)cc1>>COc1nc(C)cnc1NS(=O)(=O)c1cccnc1-c1ccc(SC)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20150210647A1,CN(C)C=O.C[C@H]1CC[C@@H](Oc2ccc3cc(F)c(Br)cc3c2)CC1>>C[C@@H]1CC[C@H](Oc2ccc3cc(F)c(C=O)cc3c2)CC1,,C1CCOC1,,[Li]CCCC,,test
US20060024330A1,CC(=O)OC(C)=O.CC1CN(C(=O)OC(C)(C)C)CC(=O)N1Cc1ccc(F)cc1>>CC(=O)N1CC(=O)N(Cc2ccc(F)cc2)C(C)C1,CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,Cl,test
US20150011548A1,CC(O)Br.NC1CC1.O=C=NS(=O)(=O)Cl>>O=C1OCCN1S(=O)(=O)NC1CC1,,ClCCl,,CCN(CC)CC,,test
US20160102073A1,Cc1ccc(C(=O)O)c(O[C@@H]2CC[C@@H](C)N(C(=O)c3ccccc3-n3nccn3)C2)n1>>Cc1ccc(CO)c(O[C@@H]2CC[C@@H](C)N(C(=O)c3ccccc3-n3nccn3)C2)n1,,C1CCOC1,,B,CSC,test
US20080058329A1,O[C@@H]1C[C@H](c2c[nH]c3ccccc23)c2ccccc21.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>[N-]=[N+]=N[C@H]1C[C@H](c2c[nH]c3ccccc23)c2ccccc21,,C1CCOC1,,C1CCC2=NCCCN2CC1,O,test
US20090029965A1,CC(C)(C)CC=O.Cc1cc(C(=O)N2Cc3cnn(C)c3Nc3ccccc32)ccc1CNC(=O)CC1CCNCC1>>Cc1cc(C(=O)N2Cc3cnn(C)c3Nc3ccccc32)ccc1CNC(=O)CC1CCN(CCC(C)(C)C)CC1,,CC(=O)O,CO,[BH3-]C#N.[Na+],,test
US20110098275A1,COC(=O)c1ccc(-c2ccnc(C)c2C#Cc2ccc(N)nc2)cc1F>>Cc1nccc(-c2ccc(C(=O)O)c(F)c2)c1C#Cc1ccc(N)nc1,,C1CCOC1,,[Na+].[OH-],,test
US20150111870A1,CON(C)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1.COc1nc2ccc(I)cc2c(Cl)c1CC1CCOCC1>>COc1nc2ccc(C(=O)C3CCN(C(=O)OC(C)(C)C)CC3)cc2c(Cl)c1CC1CCOCC1,,C1CCOC1,,[Li]CCCC,,test
US20040242608A1,CCc1c(OCc2ccc(F)cc2F)ncn(-c2cc(C(=O)O)ccc2C)c1=O.C[C@@H](N)CO>>CCc1c(OCc2ccc(F)cc2F)ncn(-c2cc(C(=O)N[C@H](C)CO)ccc2C)c1=O,CN(C)c1ccncc1,CC(=O)N(C)C,,CC(C)COC(=O)Cl,CN1CCOCC1,test
US20140371475A1,OC(CCl)CSSCC(O)CCl>>C1OC1CSSCC1CO1,,Cc1ccccc1,,CO,[Na+].[OH-],test
US20120214766A1,Fc1ccc(Br)nc1.NN>>NNc1ccc(Br)nc1,,O,,,,test
US20070213364A1,CC(C)(C)c1cc(C(C)(C)C)[nH]n1.CCOC(=O)CCc1ccc(OCc2ccc(CCl)cc2)cc1F>>CCOC(=O)CCc1ccc(OCc2ccc(Cn3nc(C(C)(C)C)cc3C(C)(C)C)cc2)cc1F,,CN(C)C=O,,O,[H-].[Na+],test
US20050054851A1,CC(C)(C)Cn1c(CBr)cc2cnc(C#N)nc21.c1nnn[nH]1>>CC(C)(C)Cn1c(Cn2cnnn2)cc2cnc(C#N)nc21,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20090124612A1,CC(C)(C)OC(=O)Cc1ccc2ncc(O)cc2c1.CO>>COc1cnc2ccc(CC(=O)OC(C)(C)C)cc2c1,,c1ccccc1,,CCCCP(CCCC)CCCC,O=C(N=NC(=O)N1CCCCC1)N1CCCCC1,test
US05136090,CCCCCCCCBr.CCOC(=O)CCc1ccc(O)c(-c2cc(CCC(=O)OCC)ccc2O)c1>>CCCCCCCCOc1ccc(CCC(=O)OCC)cc1-c1cc(CCC(=O)OCC)ccc1O,[Cu],CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050171087A1,Nc1c(Br)cccc1Br.O=Cc1ccccc1O>>Oc1ccccc1C=Nc1c(Br)cccc1Br,Cc1ccc(S(=O)(=O)O)cc1,Cc1ccccc1,,CCN(CC)CC,,test
US20110098297A1,COc1cc(Oc2ccc(S(C)(=O)=O)nc2)cc2cc(C(N)=O)[nH]c12.COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1>>COc1cc(Oc2ccc(S(C)(=O)=O)nc2)cc2cc(C(N)=S)[nH]c12,,C1CCOC1,,,,test
US20050059705A1,CC(C)(C)c1ccc(Oc2ccc3cc(C(=O)N[C@@H](Cc4ccc(Br)cc4)C(=O)O)ncc3c2)cc1.Cc1ccccc1.OB(O)c1ccc(F)c(Cl)c1>>COC(=O)[C@H](Cc1ccc(-c2ccc(F)c(Cl)c2)cc1)NC(=O)c1cc2ccc(Oc3ccc(C(C)(C)C)cc3)cc2cn1,,CCCCCC,CCOC(C)=O,,,test
US05025036,O=C(O)c1cc(OCCCCCCc2cccc(OCc3ccccc3)c2OCc2ccccc2)ccc1O>>O=C(O)c1cc(OCCCCCCc2cccc(O)c2O)ccc1O,[Pd],CO,,[H][H],,test
US20090137603A1,N#Cc1cccc(CBr)c1.OCc1ncn(C(c2ccccc2)(c2ccccc2)c2ccccc2)n1>>N#Cc1cccc(COCc2ncn(C(c3ccccc3)(c3ccccc3)c3ccccc3)n2)c1,,C1CCOC1,,[H-].[Na+],,test
US20040152699A1,CC(O)c1noc(-c2cccc(Cl)c2)n1.O=C1CCC(=O)N1Br>>CC(Br)c1noc(-c2cccc(Cl)c2)n1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20140243368A1,COP(=O)(OC)C(=[N+]=[N-])C(C)=O.COc1ccc(CN2C[C@H](C=O)CC[C@H]2C)cc1>>C#C[C@@H]1CC[C@@H](C)N(Cc2ccc(OC)cc2)C1,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20160229843A1,CNC.O=S(=O)(Cl)c1cncc(Br)c1>>CN(C)S(=O)(=O)c1cncc(Br)c1,,ClCCl,,C1CCOC1,CCN(CC)CC,test
US05496847,Brc1ccc2c(c1)OCCO2.O=C1CCC2(CC1)OCCO2>>O=C1CCC(O)(c2ccc3c(c2)OCCO3)CC1,,C1CCOC1,,[Mg],,test
US20150105403A1,N#C[Cu].Nc1ccc2scnc2c1Br>>N#Cc1c(N)ccc2scnc12,,CN1CCCC1=O,,,,test
US20070179151A1,CC(C)O.COc1cc2cc(Nc3cc(C)[nH]n3)nc(Cl)c2cc1Br>>COc1cc2cc(Nc3cc(C)[nH]n3)nc(OC(C)C)c2cc1Br,,CC(C)O,,,,test
US04547489,CC(C)[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O.NCC(=O)O.NCCCC[C@H](N)C(=O)O.N[C@@H](CC(=O)O)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O>>CC(C)[C@@H]1NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](Cc2ccc(O)cc2)NC1=O,,CO,,,,test
US20100048568A1,CC1=NNC(=O)N(N)C1.O=C(O)c1cnc(-c2cccc(F)c2)nc1>>CC1=NNC(=O)N(NC(=O)c2cnc(-c3cccc(F)c3)nc2)C1,,CN(C)C=O,,COc1nc(OC)nc([N+]2(C)CCOCC2)n1.[Cl-],,test
US05571810,CS(=O)(=O)c1ccc(-c2cc(C(N)=O)sc2-c2ccc(F)cc2)cc1>>CS(=O)(=O)c1ccc(-c2cc(C#N)sc2-c2ccc(F)cc2)cc1,,c1ccncc1,,CS(=O)(=O)Cl,,test
US20040236161A1,O=P([O-])([O-])O.O=P([O-])([O-])[O-].[K+].[K+].[K+].[K+].[K+]>>O=P([O-])([O-])O.O=P([O-])([O-])[O-].[K+].[K+].[K+].[K+].[K+],,O,,,,test
US20130082245A1,Brc1cccc(N(c2ccccc2)c2cccc(Br)n2)n1.OB(O)c1ccccc1>>Brc1cccc(N(c2ccccc2)c2cccc(-c3ccccc3)n2)n1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,O,COCCOC,O=C([O-])[O-].[K+].[K+],test
US20130059853A1,CCOC(=O)COc1c(Br)ccc(OC(F)F)c1OC>>COc1c(OC(F)F)ccc(Br)c1OCC(=O)O,,C1CCOC1,O,[Li+].[OH-],,test
US20160237090A1,COCC1CCN(c2cnn3c2CN(C(=O)OC(C)(C)C)CC3)C1>>COCC1CCN(c2cnn3c2CNCC3)C1,,CCOC(C)=O,Cl,,,test
US06794395B1,CC(C)(C)OC(=O)Cc1ccc(C(F)(F)F)cc1[N+](=O)[O-]>>O=C(O)Cc1ccc(C(F)(F)F)cc1[N+](=O)[O-],,ClCCl,,O=C(O)C(F)(F)F,,test
US20030114469A1,COc1ccc2cncc(CC(=O)O)c2c1Cl>>COc1ccc2cncc(CC(=O)O)c2c1,,[Na+],[OH-],,,test
US20160251382A1,CCCCC#CCCCC.CCCC[SnH](CCCC)CCCC>>CCCC/C=C(/CCCC)[Sn](CCCC)(CCCC)CCCC,,ClCCl,,,,test
US04670421,C1CCNCC1.C[Si](C)(C)CCCCCCCCCCCCCCNc1ccc(C(=O)Cl)cc1>>C[Si](C)(C)CCCCCCCCCCCCCCNc1ccc(C(=O)N2CCCCC2)cc1,CN(C)c1ccncc1,CCOCC,CCOCC,CCN(CC)CC,Cl,test
US20130245254A1,CC(C)N1C(=O)CNc2ncc([Sn](C)(C)C)nc21.Cc1cc(-c2ncn(C3CCCCO3)n2)c(F)cc1Br>>Cc1cc(-c2ncn(C3CCCCO3)n2)c(F)cc1-c1cnc2c(n1)N(C(C)C)C(=O)CN2,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,,,,test
US04735952,Cl.O=C(Cl)c1ccc(Nc2ccnc3cc(C(F)(F)F)ccc23)cc1.O=S(=O)(c1ccccc1F)C1CCNCC1>>Cl.O=C(c1ccc(Nc2ccnc3cc(C(F)(F)F)ccc23)cc1)N1CCC(S(=O)(=O)c2ccccc2F)CC1,,ClCCl,,CCN(CC)CC,Cl,test
US20120208994A1,Nc1ccc(F)cc1.O=Cc1ccc(OC(=O)c2ccccc2)cc1>>O=C(Oc1ccc(C=Nc2ccc(F)cc2)cc1)c1ccccc1,,CCOC(C)=O,,,,test
US20150210722A1,CC(C)c1cc(C(=O)O)n(-c2cccc(CP(C)(C)=O)c2)n1.Nc1ccc(Oc2ccnc(Cl)n2)c2ccccc12.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)n(-c2cccc(CP(C)(C)=O)c2)n1,,C1COCCO1,,CCN(CC)CC,,test
US05254546,CCCc1nc(I)c(CO)[nH]1>>CCCc1nc(I)c(C=O)[nH]1,,CC(=O)O,O,[Na+].[OH-],,test
US20080306140A1,COc1ccc(-c2coc3c(C)c(OC(C)=O)ccc3c2=O)cc1OC>>COc1ccc(C2COc3c(ccc(OC(C)=O)c3C)C2O)cc1OC,,CCO,,[H][H],,test
US20020049239A1,CC[Sn](CC)(CC)CC.O=[N+]([O-])c1cc(Br)c2scnc2c1>>CCc1cc([N+](=O)[O-])cc2ncsc12,,CCOC(C)=O,,,,test
US20060241127A1,N#Cc1ccc(N)cc1.Nc1nc(Cl)cc(Cl)n1>>N#Cc1ccc(Nc2cc(Cl)nc(N)n2)cc1,,O,,Cl,,test
US20150353535A1,CCOC(=O)C1C2CCC1CC(=O)C2.c1cscn1>>CCOC(=O)C1C2CCC1CC(O)(c1nccs1)C2,,C1CCOC1,,[Li]CCCC,,test
US20050203078A1,COCC[C@H](N)c1nc2cc(Cl)ccc2[nH]1.Cc1cc(C(=O)O)ccc1N1CCOCC1=O>>COCC[C@H](NC(=O)c1ccc(N2CCOCC2=O)c(C)c1)c1nc2cc(Cl)ccc2[nH]1,,C1CCOC1,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20120101083A1,CC(C)Nc1ncc(-c2nc(-c3ccc4c(c3)CCNCC4)no2)cc1C#N.Cl.O=C[C@@H](O)CO>>CC(C)Nc1ncc(-c2nc(-c3ccc4c(c3)CCN(C[C@@H](O)CO)CC4)no2)cc1C#N.Cl,,CO,ClCCl,O=C([O-])O.[Na+],,test
US20090192162A1,CCOC(=O)COc1ccc(Sc2cc(C#Cc3ccc(Cl)cc3)cc(OCCCN3CCOCC3)c2)cc1Cl>>O=C(O)COc1ccc(Sc2cc(C#Cc3ccc(Cl)cc3)cc(OCCCN3CCOCC3)c2)cc1Cl,,CCO,,Cl,[Na+].[OH-],test
US20070299092A1,COC(C)O.COCCOc1cc2ncnc(NC3=CC(=O)C(Oc4ccccc4)=CC3=O)c2cc1OC>>COCCOC1=CC(=O)C(Nc2ncnc3cc(OCCOC)c(OC)cc23)=CC1=O,,CCN(CC)CC,,,,test
US20040242573A1,BrCCOCCBr.C[C@H](N)c1ccc(Br)cc1>>C[C@@H](c1ccc(Br)cc1)N1CCOCC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20050130992A1,CC(=O)OCc1cc(-c2cnn3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)ccn1>>OCc1cc(-c2cnn3c(C(F)(F)F)cc(-c4ccc(C(F)(F)F)cc4)nc23)ccn1,,CO,,O,C[O-].[Na+],test
US20110060156A1,CC(=O)C(=O)Cl.O=C(O)c1ccc(O)cc1O>>CC(=O)C(=O)Oc1cc(O)ccc1C(=O)O,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20100210704A1,CC(=O)Nc1cc(OCC(F)(F)C(F)(F)F)nn1-c1cc(S)c(C)cc1F.O=S(=O)(OCC(F)(F)Cl)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>CC(=O)Nc1cc(OCC(F)(F)C(F)(F)F)nn1-c1cc(SCC(F)(F)Cl)c(C)cc1F,,CN(C)C=O,,O=C([O-])[O-].[Na+].[Na+],,test
US20040043994A1,CCOC(=O)CC(C)(C)Cc1cc(Br)c(O)c(OC)c1Br>>CCOC(=O)CC(C)(C)Cc1ccc(O)c(OC)c1,[Pd],CCO,,CCN(CC)CC,,test
US20030069242A1,CCCS.COC(=O)c1ccc(-c2c[nH]nc2C(F)(F)F)cc1Cl>>CCCSc1cc(-c2c[nH]nc2C(F)(F)F)ccc1C(=O)OC,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150299189A1,COC(=O)c1cc(Cl)ccc1Nc1ccc2c(ccn2Cc2cccc(O)c2)c1.NC(=O)CBr>>COC(=O)c1cc(Cl)ccc1Nc1ccc2c(ccn2Cc2cccc(OCC(N)=O)c2)c1,,CCOC(C)=O,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],test
US20110071197A1,COC(=O)c1cc(Oc2ccc([N+](=O)[O-])c(C(=O)OC)c2)ccc1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1cc(Oc2ccc([N+](=O)[O-])c(C(=O)OC)c2)ccc1OS(=O)(=O)C(F)(F)F,,CCOC(C)=O,O,ClCCl,c1ccncc1,test
US05248825,CCOc1ccc(CO)cc1.O=Cc1cccc(O)c1>>CCOc1ccc(COc2cccc(C=O)c2)cc1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090042876A1,CCC(=O)[O-].Nc1ccc2[nH]c(=O)c3[nH]ccc3c2c1.O=S(=O)(Cl)c1ccccc1>>CCC(=O)[O-].O=c1[nH]c2ccc(NS(=O)(=O)c3ccccc3)cc2c2cc[nH]c12,,CN(C)C=O,,CCN(CC)CC,,test
US20150175601A1,CN1CCC(Nc2ccc([N+](=O)[O-])cc2)CC1>>CN1CCC(Nc2ccc(N)cc2)CC1,[Pd],CO,,,,test
US20090131378A1,C=C1/C(=C\C=C2/CCC[C@@]3(C)[C@H]2CC[C@@H]3[C@]2(C)C[C@@H](CC(C)(C)O)CO2)C[C@@H](O[Si](CC)(CC)CC)C[C@@H]1O[Si](CC)(CC)CC>>C=C1/C(=C\C=C2/CCC[C@@]3(C)[C@H]2CC[C@@H]3[C@]2(C)C[C@H](CC(C)(C)O)CO2)C[C@@H](O)C[C@@H]1O,,CC#N,CCN(CC)CC,,,test
US20100261698A1,CC(C)(C)C(=O)OCCl.CCOC(C)=O.CN(C)C=O.Cc1c(-c2cccnc2)[nH]c2ccc(C#N)cc12>>Cc1c(-c2cccnc2)n(COC(=O)C(C)(C)C)c2ccc(C#N)cc12.[NH4+].[OH-],,CCOC(C)=O,,[H-].[Na+],,test
US20130172323A1,BrCc1ccccc1.CC(Cl)C(=O)c1ccc2[nH]c(=O)oc2c1>>CC(Cl)C(=O)c1ccc2c(c1)oc(=O)n2Cc1ccccc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090163709A1,CCOCOc1ccc(OC)c(OCOCC)c1C>>COc1ccc(O)c(C)c1O,,CO,,Cl,O,test
US04618359,O=C(Cl)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Br.OC1CCOC1>>O=C(OC1CCOC1)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1Br,,Cc1ccccc1,,CCN(CC)CC,,test
US03998879,CCCC1CC(=O)CC(=O)C1.Cc1ccc(S(=O)(=O)N=C=O)cc1>>CCCC1CC(=O)C(C(=O)NS(=O)(=O)c2ccc(C)cc2)C(=O)C1,,c1ccccc1,,,,test
US20160108056A1,COC(=O)c1cc2cc(Cl)c(Br)cc2s1.CS(N)(=O)=O>>COC(=O)c1cc2cc(Cl)c(NS(C)(=O)=O)cc2s1,,C1COCCO1,,CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21,O=C([O-])[O-].[Cs+].[Cs+],test
US20020098443A1,COCCl.OCCN1CCCC1>>COCOCCN1CCCC1,,CCOC(C)=O,O,C1CCOC1,CCN(CC)CC,test
US20110118484A1,COC(=O)C(O)C1CCCCCC=C1Br>>O=C(O)C(O)C1C#CCCCCC1,,CS(C)=O,,C1CCC2=NCCCN2CC1,Cl,test
US20030144280A1,CC(=O)c1ccc(O)c(F)c1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC(=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(F)c1,,c1ccncc1,,,,test
US20110112122A1,CC(C)(C)OC(=O)c1c(S(=O)(=O)c2ccccc2)ccc2c1c1c(n2COCC[Si](C)(C)C)CC2CCC1N2>>CC(C)(C)OC(=O)c1c(S(=O)(=O)c2ccccc2)ccc2[nH]c3c(c12)C1CCC(C3)N1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04206120,COC(=O)CBr.CSC1CC(=O)N1>>COC(=O)CN1C(=O)CC1SC,,CN(C)C=O,O,[H-].[Na+],,test
US20110201593A1,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](C(=O)O)C1.OCc1ccccc1.[N-]=[N+]=NP(=O)(c1ccccc1)c1ccccc1>>CC(C)(C)OC(=O)N[C@H]1CC[C@@H](NC(=O)OCc2ccccc2)C1,CN(C)c1ccncc1,Cc1ccccc1,,CCN(CC)CC,,test
US20120022041A1,CC(C)(C)OC(=O)C1CN(Cc2ccc(-c3noc(-c4noc(-c5ccccn5)c4C(F)(F)F)n3)cc2)C1>>O=C(O)C1CN(Cc2ccc(-c3noc(-c4noc(-c5ccccn5)c4C(F)(F)F)n3)cc2)C1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06509361B1,CS(=O)(=O)[O-].Cc1cccc(-n2nc(C)cc2-c2ccnc(Cl)c2)c1>>Cc1cccc(-n2nc(C)cc2-c2ccnc(S(C)(=O)=O)c2)c1,,CN(C)C=O,,O,,test
US20160168122A1,Cc1cc(Br)cc(F)c1C(=O)O.N>>Cc1cc(Br)cc(F)c1C(N)=O,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US20010000513A1,Brc1ccc(-c2ccccc2)cc1.COC(=O)CCC(=O)Cl>>COC(=O)CCC(=O)c1ccc(-c2ccc(Br)cc2)cc1,,ClCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20150152112A1,O=C(O)c1c(O)cc(=O)n2c1CC[C@H]2C(=O)O>>O=C(O)[C@@H]1CCc2cc(O)cc(=O)n21,,Cl,,,,test
US20090198063A1,CCOC(=O)/C=C/c1ncc(OC)cc1N>>COc1cnc2ccc(=O)[nH]c2c1,,CO,,C[O-].[Na+],,test
US20100190775A1,CSc1ncc2c(n1)N1CCC[C@H]1CN(c1cccc(C(=O)NN)c1)C2=O.S=C=S>>CSc1ncc2c(n1)N1CCC[C@H]1CN(c1cccc(-c3nnc(S)o3)c1)C2=O,,CCO,,[K+].[OH-],,test
US05516788,COc1ccc2[nH]c3c(c2c1)Cc1ccccc1-3>>COc1ccc2c(c1)[C@H]1Cc3ccccc3[C@H]1N2,,CC(=O)O,,[Na+].[OH-],,test
US20030055265A1,CCO/C(=C\c1ccc(OCCc2nc(-c3ccccc3)oc2C)c2sccc12)C(=O)O>>CCOC(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)c2sccc12)C(=O)O,,CCO,,,,test
US05840764,CC(C)(C)N.CCOc1c(Nc2c(C)cccc2O)c(=O)c1=O>>Cc1cccc(O)c1Nc1c(NC(C)(C)C)c(=O)c1=O,,ClCCl,,,,test
US05616610,CCC=O.COc1ccc(F)c2c1C[C@@H](NC1CCCC1)CO2>>CCCN(C1CCCC1)[C@H]1COc2c(F)ccc(OC)c2C1,,CO,,[BH3-]C#N.[Na+],,test
US05643932,CCOc1ccc(-c2nc(-c3ccc(O[C@@H]4O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]4OC(C)=O)cc3)cs2)cc1OCC>>CCOc1ccc(-c2nc(-c3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc3)cs2)cc1OCC,,CO,ClCCl,C[O-].[Na+],,test
US20110224247A1,CCCN(C(=O)OC(C)(C)C)n1c(C)c(C(=O)O)c2cnccc2c1=O.CCN(CC)CC.CN(C)C=O.ClCCl.O=C(O)C(F)(F)F.On1nnc2ccccc21>>CCCNn1c(C)c(C(=O)N[C@H](c2ccc(F)cc2)C2CC2)c2cnccc2c1=O,,ClCCl,,CCN=C=NCCCN(C)C,Cl,test
US20150087639A1,CCNCC.O=[N+]([O-])c1ccc(F)c(F)c1>>CCN(CC)c1ccc([N+](=O)[O-])cc1F,,CCOC(C)=O,,CCN(CC)CC,,test
US04603012,C=C(C1C(C)(C)CCC1(C)C)C1(NC(=O)OC(C)(C)C)CC1>>C=C(C1C(C)(C)CCC1(C)C)C1(N)CC1,,O=C(O)C(F)(F)F,,O,[K+].[OH-],test
US20120123050A1,C[Si](C)(CCCCOc1ccc([N+](=O)[O-])cc1F)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)CCCCOc1ccc([N+](=O)[O-])cc1F>>C[Si](C)(CCCCOc1ccc(N)cc1F)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)CCCCOc1ccc(N)cc1F,[Pd],,,,,test
US05843957,C#CCOc1cccc(-c2c(NC(=O)Nc3c(C(C)C)cccc3C(C)C)c(=O)n(CCCC)c3ncccc23)c1.C=O.CCNCC>>CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(OCC#CCN(CC)CC)c2)c2cccnc21,[Cu]I,C1COCCO1,,CCOCC,,test
US20100087429A1,CC(C)(C)CCc1ccc2c(c1)C1(COC(N)=N1)c1cc(-c3cncnc3)ccc1O2>>CC(C)(C)CCc1ccc2c(c1)[C@@]1(COC(N)=N1)c1cc(-c3cncnc3)ccc1O2,,CO,,O=C=O,,test
US20080188528A1,Fc1cc(F)cc(CBr)c1.O=C(O)c1cccnc1O>>O=C(O)c1cccn(Cc2cc(F)cc(F)c2)c1=O,,CO,,O,[K+].[OH-],test
US08088784B2,C[C@H](N)c1ncc(F)cn1.Cc1cc(Nc2cc(N(C)S(=O)(=O)N(C)C)nc(Cl)n2)n[nH]1>>Cc1cc(Nc2cc(N(C)S(=O)(=O)N(C)C)nc(N[C@@H](C)c3ncc(F)cn3)n2)n[nH]1,,CCCCO,,CCN(C(C)C)C(C)C,Cl,test
US04436892,O=C(Cl)c1c(Cl)cccc1[N+](=O)[O-].c1ccc(-c2ncc[nH]2)cc1>>O=C(c1c(Cl)cccc1[N+](=O)[O-])n1ccnc1-c1ccccc1,,C1CCOC1,,CCN(CC)CC,,test
US20090062251A1,CCNCC(=O)NCC.O=C(O)c1ccc2c(c1)c1c(n2CCF)CCC(C2CCOCC2)C1>>CCNC(=O)CN(CC)C(=O)c1ccc2c(c1)c1c(n2CCF)CCC(C2CCOCC2)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05679683,NC(=O)c1cc(O)c([N+](=O)[O-])cc1[N+](=O)[O-]>>NC(=O)c1cc(O)c(N)cc1N,[Pd],CCOC(C)=O,CO,,,test
US20050113370A1,CC(C)(C)OC(=O)n1nc(-c2ccccc2)c2ccc(NCc3ccccc3)cc21.Cl>>Cl.c1ccc(CNc2ccc3c(-c4ccccc4)n[nH]c3c2)cc1,,CCOCC,CO,,,test
US20030073697A1,COC(=O)Nc1ccc2c(c1C=O)O[C@@H](COS(=O)(=O)c1ccc(C)cc1)CO2.O=C(OO)c1cccc(Cl)c1>>COC(=O)Nc1ccc2c(c1O)OC(COS(=O)(=O)c1ccc(C)cc1)CO2,,CO,ClCCl,,,test
US20050203078A1,CCOC(=O)CCOCCCl>>O=C(O)CCOCCCl,,CCO,,[Li+].[OH-],,test
US20050288357A1,CC(C)(C)OC(=O)CC[C@@H](N)C(=O)OC(C)(C)C.COC(=O)c1ccc(CC=O)cc1>>COC(=O)c1ccc(CCN2C(=O)CC[C@@H]2C(=O)OC(C)(C)C)cc1,,CCOC(C)=O,CO,CC(=O)O,[BH3-]C#N.[Na+],test
US20020077491A1,BrCc1ccccc1.O=C(O)c1cc(O)c2ccccc2n1>>O=C(OCc1ccccc1)c1cc(O)c2ccccc2n1,,CN1CCCC1=O,,O,[H-].[Na+],test
US20090175794A1,NC1CCc2cc(S(N)(=O)=O)ccc21.O=C(Cl)c1ccc(I)cc1>>NS(=O)(=O)c1ccc2c(c1)CCC2NC(=O)c1ccc(I)cc1,,ClCCl,,CCN(CC)CC,Cl,test
US04675324,CCC(=O)N1CCC(=O)c2cc(O)ccc21.O=C1CCC(=O)N1Cl>>CCC(=O)N1CCC(=O)c2c1ccc(O)c2Cl,,CN(C)C=O,,O,,test
US20100261755A1,COC(=O)N1CC[C@@H](c2cc(=O)[nH]o2)C[C@@H]1Cc1cccc(C(F)(F)F)c1>>O=c1cc([C@@H]2CCN[C@@H](Cc3cccc(C(F)(F)F)c3)C2)o[nH]1,,Br,,,,test
US05089514,COC(Cc1ccc2oc(Cc3nc(-c4ccccc4)oc3C)cc2c1)OC.C[Si](C)(C)C#N>>COC(C#N)Cc1ccc2oc(Cc3nc(-c4ccccc4)oc3C)cc2c1,,ClCCl,,CCOCC,FB(F)F,test
US20050256103A1,CC(=O)OC(C)=O.COc1cc2c(cc1CCN1CCC3(CC1)OCCO3)NCCC2>>COc1cc2c(cc1CCN1CCC3(CC1)OCCO3)N(C(C)=O)CCC2,,c1ccncc1,,,,test
US20060079572A1,C1COCCN1.CCOC(C)OC1CCC(C)(OC(C)OCC)C(OC(=O)CCl)C=CC(C)C(/C(C)=C/C=C/C(C)CC2OC2C(C)C(CC)OC(C)OCC)OC(=O)C1>>CCOC(C)OC1CCC(C)(OC(C)OCC)C(OC(=O)CN2CCOCC2)C=CC(C)C(/C(C)=C/C=C/C(C)CC2OC2C(C)C(CC)OC(C)OCC)OC(=O)C1,,CN(C)C=O,,CCOC(C)=O,O,test
US20070093526A1,COC(CSc1ccccc1C)OC>>Cc1cccc2ccsc12,,Clc1ccccc1,,O,,test
US05736284,C=C(c1ccccc1)c1ccccc1.C=O.Cl>>ClCC=C(c1ccccc1)c1ccccc1,,O,,CC(=O)O,,test
US20100093748A1,CC(C)(C)OC(=O)NC1(c2nc3ccccc3[nH]2)CCN(C(=O)OC(C)(C)C)CC1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)NC1(c2nc3ccccc3n2C(=O)OC(C)(C)C)CCN(C(=O)OC(C)(C)C)CC1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,,test
US20090054478A1,CCCCCCNC(=O)n1[nH]c2nc(Cl)cc(C)c2c1=O.CCCCI>>CCCCCCNC(=O)n1c(=O)c2c(C)cc(Cl)nc2n1CCCC,,CN(C)C=O,,CCN(CC)CC,,test
US20050182072A1,CC(C)(C)OC(=O)N1C[C@@H]2CC1CN2.CSc1nc(Cl)cc(-c2ccnc(Cl)c2)n1>>CSc1nc(-c2ccnc(Cl)c2)cc(N2CC3CC2CN3C(=O)OC(C)(C)C)n1,,CCOC(C)=O,,CC#N,O=C([O-])[O-].[K+].[K+],test
US06433175B1,CN(C)C=O.COc1ccc2[nH]ccc2c1>>COc1ccc2[nH]cc(C=O)c2c1,,O,,O=P(Cl)(Cl)Cl,[Na+].[OH-],test
US06455523B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CS(=O)(=O)N1Cc2cc(C#N)ccc2N(Cc2c[nH]cn2)C[C@H]1Cc1ccccc1>>CC(C)(C)OC(=O)n1cnc(CN2C[C@@H](Cc3ccccc3)N(S(C)(=O)=O)Cc3cc(C#N)ccc32)c1,CN(C)c1ccncc1,ClCCl,,Cl,,test
US04582834,COc1ccc(-c2c[nH]c(=O)nc2C)cc1.Cl>>COc1ccc(-c2c[nH]c(=O)nc2C)cc1.Cl,,CO,,CCOCC,,test
US20110021493A1,CN(C)C(=O)N1CCNCC1.Clc1ccc(Nc2ncnc3sc4c(c23)CCNC4)cc1Cl.O=C(O)/C=C/CBr>>CN(C)C(=O)N1CCN(C/C=C/C(=O)N2CCc3c(sc4ncnc(Nc5ccc(Cl)c(Cl)c5)c34)C2)CC1,,ClCCl,O,CCN(C(C)C)C(C)C,CCN=C=NCCCN(C)C,test
US20120121783A1,O=C(/C=C/c1ccccn1)c1ccc2c(c1O)OCO2>>O=C(CCc1ccccn1)c1ccc2c(c1O)OCO2,[Pd],CO,,,,test
US05708101,C1=CCC=C1.CC(C)(C)C=O.CO>>C=C1C=CC=C1C(C)(C)C,,CO,,C1CCNC1,,test
US20140088101A1,CCCC[Sn](CCCC)(CCCC)c1cccnc1.COC(=O)c1nc(Br)c2c(cc(-c3ccccc3)c(=O)n2CCc2ccccc2)c1O>>COC(=O)c1nc(-c2cccnc2)c2c(cc(-c3ccccc3)c(=O)n2CCc2ccccc2)c1O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CN(C)C=O,O,CCOC(C)=O,Cl,test
US20050101614A1,Cn1nc2c(Br)cccc2c1Cl.OB(O)c1ccc(Cl)cc1Cl>>Cn1nc2c(-c3ccc(Cl)cc3Cl)cccc2c1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US20120202777A1,CCOC(=O)CS(C)(=O)=O.ICCc1ccc(OCc2ccccc2)cc1>>CCOC(=O)C(CCc1ccc(OCc2ccccc2)cc1)S(C)(=O)=O,,CN(C)C=O,,[H-].[Na+],,test
US06156801,O=C1c2ccccc2C(=O)N1CCCBr.O=[N+]([O-])c1cc(O)ccc1Cl>>O=C1c2ccccc2C(=O)N1CCCOc1ccc(Cl)c([N+](=O)[O-])c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US06194450B1,Nc1ccc(C(=O)O)c(O)c1.[I-]>>O=C(O)c1ccc(I)cc1O,[Cu]I,O,O=S(=O)(O)O,O=N[O-].[Na+],,test
US20140107073A1,Brc1ccc2ncc(I)n2c1.COc1cc(B(O)O)cc(OC)c1OC>>COc1cc(-c2cnc3ccc(Br)cn23)cc(OC)c1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20130102609A1,CC(C)(C)OC(=O)CBr.CS(=O)(=O)c1cc(-c2cc(C=O)ccc2O)ccc1F>>CC(C)(C)OC(=O)COc1ccc(C=O)cc1-c1ccc(F)c(S(C)(=O)=O)c1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080161294A1,C[C@H](CO)N(Cc1ccccc1NS(=O)(=O)c1ccccc1[N+](=O)[O-])C(=O)OC(C)(C)C>>C[C@@H]1CN(S(=O)(=O)c2ccccc2[N+](=O)[O-])c2ccccc2CN1C(=O)OC(C)(C)C,,c1ccccc1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20120053162A1,CC(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@]4(C)[C@@H](c5ccc(=O)oc5)CC[C@]4(O)[C@@H]3CC[C@@H]2C1>>CC(C)C[C@@H](N)C(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@@]4(C)C(=CC[C@@H]4c4ccc(=O)oc4)[C@@H]3CC[C@@H]2C1,,CCOC(C)=O,,Cl,,test
US20150166507A1,C#CCNC(=O)c1cccnc1Cl.Nc1cccc(F)c1>>C#CCNC(=O)c1cccnc1Nc1cccc(F)c1,,OCCO,,,,test
US20060293337A1,CCOC(=O)C1CCN(c2ccc3c(C(=O)NCCC4CCCCC4)c(Cl)ccc3n2)CC1>>O=C(NCCC1CCCCC1)c1c(Cl)ccc2nc(N3CCC(C(=O)O)CC3)ccc12,,O,,CO,[K+].[OH-],test
US05171753,NCC(O)CO.c1ccc([C@H]2O[C@@H]2c2ccccc2)cc1>>OCC(O)CNC(c1ccccc1)C(O)c1ccccc1,,CO,,O,,test
US04868183,CC(C)(C)C1=CC(=O)C=C(C(C)(C)C)C1=O.Nc1cc[nH]n1>>CC(C)(C)C1=CC(=Nc2cc[nH]n2)C=C(C(C)(C)C)C1=O,CC(=O)O,,,,,test
US20120059028A1,CCCC(C(=O)OCC)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1)CCN(C)C3>>CCCC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1)CCN(C)C3,,CCO,CO,[Na+].[OH-],,test
US20100310512A1,CC(C)(C)OC(=O)N1C2CCC(C2)C1c1nc2ccc(B3OC(C)(C)C(C)(C)O3)cc2[nH]1.CC(C)(C)OC(=O)N1CCCC1c1ncc(-c2ccc3c(c2)CCc2cc(Br)ccc2-3)[nH]1>>CC(C)(C)OC(=O)N1CCCC1c1ncc(-c2ccc3c(c2)CCc2cc(-c4ccc5nc(C6C7CCC(C7)N6C(=O)OC(C)(C)C)[nH]c5c4)ccc2-3)[nH]1,,COCCOC,O,O=C([O-])O.[Na+],,test
US20110039835A1,CCOC(=O)Cl.COC(=O)C(CNCCNC(=O)OC(C)(C)C)N1C(=O)c2ccccc2C1=O>>CCOC(=O)N(CCNC(=O)OC(C)(C)C)CC(C(=O)OC)N1C(=O)c2ccccc2C1=O,,ClCCl,,CCN(CC)CC,[Cl-].[NH4+],test
US20070105833A1,CNC.COc1ccccc1-c1cc(C(N)=O)nc(S(C)=O)n1>>COc1ccccc1-c1cc(C(N)=O)nc(N(C)C)n1,,C1COCCO1,,CCN(C(C)C)C(C)C,Cl,test
US20070208007A1,CCCN(CCC)Cc1cccc(C(=O)OC)c1>>CCCN(CCC)Cc1cccc(C(=O)O)c1,,CO,,[Na+].[OH-],,test
US04721523,C#CCOC(=O)N(CC(C)(C)C)C(=O)C(=O)Cl.CO>>C#CCOC(=O)N(CC(C)(C)C)C(=O)C(=O)OC,,Cc1ccccc1,,CCN(CC)CC,,test
US20070021380A1,CO[C@H]1O[C@H](CN=[N+]=[N-])[C@@H](O)[C@H](O)[C@H]1O>>[N-]=[N+]=NC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O,,O,,,,test
US04981865,Cc1ccc(Cl)c(Nc2ccccc2C(=O)CS(C)=O)c1Cl>>CC(=O)c1ccccc1Nc1c(Cl)ccc(C)c1Cl,,C1CCOC1,O,[Al],,test
US20140322229A1,COC(=O)c1ccc(Sc2c3n(c4ccccc24)CN(C)CC3)cc1.NO>>CN1CCc2c(Sc3ccc(C(=O)NO)cc3)c3ccccc3n2C1,,CO,,Cl,C[O-].[Na+],test
US20140194469A1,CCOC(=O)/C(C)=C/N(C)C.N#Cc1ccnc(NN)c1>>CCOC(=O)/C(C)=C/NNc1cc(C#N)ccn1,,CC(=O)O,CCO,,,test
US20130079313A1,BrCc1ccccc1.CC(C)(O)C(=O)O>>CC(C)(O)C(=O)OCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20160007598A1,CC1=C(C2CC2)C(=O)CC(C)(C)C1(O)C#C/C(C)=C\CO>>CC1=C(C2CC2)C(=O)CC(C)(C)C1(O)/C=C/C(C)=C\C=O,,C1CCOC1,,Cc1ccccc1,O,test
US20080009530A1,CC(C)Oc1cc(CCCN)n(Cc2ccc(Cl)cc2Cl)n1.O=C=NS(=O)(=O)c1ccccc1>>CC(C)Oc1cc(CCCNC(=O)NS(=O)(=O)c2ccccc2)n(Cc2ccc(Cl)cc2Cl)n1,,CC#N,,,,test
US20100130556A1,COC(=O)C=Cc1ccc(F)c(N)c1.O=C(O)c1ccc(-c2ccccc2)o1>>COC(=O)C=Cc1ccc(F)c(NC(=O)c2ccc(-c3ccccc3)o2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20110311466A1,CC(C)(C)OC(=O)N1CC(c2ccc(OCc3ccccc3)cc2OCc2ccccc2)C1.O=C(O)C(F)(F)F>>O=C(O)C(F)(F)F.c1ccc(COc2ccc(C3CNC3)c(OCc3ccccc3)c2)cc1,,ClCCl,,,,test
US20100048567A1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1N.NC(=O)c1cnc(On2nnc3ccccc32)nc1Nc1ccc(-c2cscn2)c(F)c1>>NC(=O)c1cnc(N[C@@H]2CCCC[C@@H]2N)nc1Nc1ccc(-c2cscn2)c(F)c1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,O=C(O)C(F)(F)F,test
US20100048551A1,NNc1cccc(C(F)(F)F)c1.Oc1ccnc(O)c1>>Oc1nccc2[nH]c3cc(C(F)(F)F)ccc3c12,,c1ccc(Oc2ccccc2)cc1,,Cc1ccccc1,,test
US04673746,CCCC(Oc1ccc2c(-c3ccc(Cl)cc3)noc2c1)C(=O)OCC>>CCCC(Oc1ccc2c(-c3ccc(Cl)cc3)noc2c1)C(=O)O,,CO,,[Na+].[OH-],,test
US20070072893A1,CC(C)(C)[Si](C)(C)OCCCCn1cnc2cnc3ccccc3c21>>OCCCCn1cnc2cnc3ccccc3c21,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05753679,O=C(OC1CCN(Cc2ccccc2)CC1)c1cccc([N+](=O)[O-])c1>>Nc1cccc(C(=O)OC2CCN(Cc3ccccc3)CC2)c1,[Ni],CCO,,,,test
US20100331335A1,COC(=O)Cn1c(=O)ccc2ccc(Br)cc21.N#C[Cu]>>COC(=O)Cn1c(=O)ccc2ccc(C#N)cc21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOCC,CN(C)C=O,,,test
US20150119387A1,Cc1cc(-c2ccc(CNc3nccc4cc(Br)ccc34)cn2)ccn1.OB(O)c1cccc(F)c1>>Cc1cc(-c2ccc(CNc3nccc4cc(-c5cccc(F)c5)ccc34)cn2)ccn1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,C1COCCO1,O=C([O-])[O-].[Na+].[Na+],test
US20080009482A1,CNC(=O)CCN(Cc1cc(OC)cc(OC)c1)c1nc(Cl)ncc1Br>>CN1C(=O)CCNc2nc(Cl)ncc21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110034460A1,OCc1cc(CCN2CCCC2)c[nH]1>>O=Cc1cc(CCN2CCCC2)c[nH]1,O=[Mn]=O,C1CCOC1,,,,test
US20120071512A1,CN1C(=O)C(=O)c2c(C3CC3)cccc21>>CN1C(=O)Cc2c(C3CC3)cccc21,,ClCCl,O,NN,,test
US20110028466A1,O=[N+]([O-])c1cn2c(n1)OC(CO)CC2.Oc1ccc(I)cc1>>O=[N+]([O-])c1cn2c(n1)OC(COc1ccc(I)cc1)CC2,,C1CCOC1,,CCOC(=O)/N=N/C(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20080171748A1,CI.COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)[C@@H](CCNC(C)=O)C[C@@H]3c3ccc(OC)cc3)cc21>>COCCCN1CCOc2ccc(CO[C@H]3CN(S(=O)(=O)c4ccc(C)cc4)[C@@H](CCN(C)C(C)=O)C[C@@H]3c3ccc(OC)cc3)cc21,,CN(C)C=O,Cl,[H-].[Na+],,test
US20100305133A1,COC(=O)c1c(OC)ccc2nc(-c3ccccc3)c(-c3nccs3)nc12>>O=C(O)c1c(O)ccc2nc(-c3ccccc3)c(-c3nccs3)nc12,,ClCCl,,BrB(Br)Br,O,test
US20030120069A1,C=C1CC(CO[Si](C)(C)C(C)(C)C)N(C(=O)c2cc([N+](=O)[O-])c(OCCCOc3cc(OC)c(C(=O)N4CC(=C)C[C@H]4CO[Si](C)(C)C(C)(C)C)cc3[N+](=O)[O-])cc2OC)C1>>C=C1CC(CO)N(C(=O)c2cc([N+](=O)[O-])c(OCCCOc3cc(OC)c(C(=O)N4CC(=C)C[C@H]4CO)cc3[N+](=O)[O-])cc2OC)C1,,C1CCOC1,,[Cl-].[NH4+],CCCC[N+](CCCC)(CCCC)CCCC.[F-],test
US20070185144A1,Cc1cc(C[C@H]2[C@@H](CO[Si](C)(C)C(C)(C)C)OC(C)(C)N2C(=O)OC(C)(C)C)cc(Cl)n1>>Cc1cc(C[C@H]2[C@@H](CO)OC(C)(C)N2C(=O)OC(C)(C)C)cc(Cl)n1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20090182007A1,CI.COC(=O)c1cncn1C1c2ccccc2C(=O)NC1(C)C>>COC(=O)c1cncn1C1c2ccccc2C(=O)N(C)C1(C)C,,CN(C)C=O,,[H-].[Na+],,test
US04985444,COC(=O)CCn1nc(-c2c(-c3ccccc3)nn3ccccc23)ccc1=O>>O=C(O)CCn1nc(-c2c(-c3ccccc3)nn3ccccc23)ccc1=O,,CO,,[Na+].[OH-],,test
US05643872,CC(C)(C)OC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O.Cc1ccc(CO[C@@H]2[C@@H](CO)OC(O)[C@@H](O)[C@H]2O)cc1>>Cc1ccc(CO[C@@H]2[C@@H](CO)OC(O)[C@@H](O)[C@H]2O)cc1.O=C(O)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US03969373,COC(OC)OC.O=Cc1ccc(C=CC(=O)O)cc1>>O=C(O)C=Cc1ccc(C(=O)O)cc1,,CO,,,,test
US04146627,CCOC(=O)C1=C(C)NC(N)=C(C(=O)OCC)C1c1ccccc1.COC(OC)N(C)C>>CCOC(=O)C1=C(C)NC(N=CN(C)C)=C(C(=O)OCC)C1c1ccccc1,,CCOCC,,,,test
US20110053906A1,CN(C)C=O.O=c1[nH]c2ncccc2c2cc(F)ccc12.OCc1cccc(Br)c1>>CC(C)(C)Oc1ccc2c(=O)[nH]c3ncccc3c2c1,,CN(C)C=O,CO,O=C([O-])[O-].[K+].[K+],,test
US20140275179A1,CCOC(=O)CC1CCc2cc(OC)ccc21>>CCOC(=O)CC1CCc2cc(O)ccc21,,ClCCl,,BrB(Br)Br,,test
US20060247287A1,CC(C)(C)OC(=O)NCC(=O)Nc1cccc(-c2cc(-c3c(Cl)cccc3Cl)no2)c1>>CC(C)(C)OC(=O)NCCNc1cccc(-c2cc(-c3c(Cl)cccc3Cl)no2)c1,,C1CCOC1,,B,,test
US04237278,CC(C)(C)N.Cc1nnc(C=Cc2ccccc2OCC(O)CCl)s1>>Cc1nnc(C=Cc2ccccc2OCC(O)CNC(C)(C)C)s1,,C1COCCO1,,,,test
US05736568,C1CCNCC1.C=O.Oc1ccc(Cl)cc1>>Oc1ccc(Cl)cc1CN1CCCCC1,,CCO,,,,test
US20150376136A1,CN1C(=O)NC(=O)C1(C)Cc1ccccc1Cl.O=C(CBr)c1ccccc1>>CN1C(=O)N(CC(=O)c2ccccc2)C(=O)C1(C)Cc1ccccc1Cl,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20100016279A1,COC(=O)c1ccc2[nH]cc(C3CCNCC3)c2c1.FC(F)(F)c1nnc2ccc(Cl)nn12>>COC(=O)c1ccc2[nH]cc(C3CCN(c4ccc5nnc(C(F)(F)F)n5n4)CC3)c2c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US04070373,N#CC=C1c2ccccc2COc2ccccc21>>N#CCC1c2ccccc2COc2ccccc21,,O,,,,test
US20070197537A1,CCN(CC)CC#Cc1cc2nccc(Oc3ccc(N)cc3F)c2s1>>CCCc1cc2nccc(Oc3ccc(N)cc3F)c2s1,[Pd],CCO,ClCCl,C1COCCO1,Cl,test
US20120129105A1,C=COCCCl.O=C(O)c1ccc2ccccc2c1>>C=COCCC(=O)c1ccc2ccccc2c1,,C1COCCO1,ClC(Cl)Cl,CO,O=C([O-])[O-].[K+].[K+],test
US05652237,CCOC=O.Nc1ccccc1I>>O=CNc1ccccc1I,,C1CCOC1,,[H-].[Na+],,test
US04808589,CN(C)Cc1ccnc(CSCCC#N)c1.CO>>COC(=N)CCSCc1cc(CN(C)C)ccn1,,CO,ClC(Cl)Cl,Cl,O=C([O-])[O-].[K+].[K+],test
US20130045942A1,CC(O)CNCC(C)O.OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O>>CC(O)CN(CC(C)O)c1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O,,CCO,,,,test
US20050054683A1,O=C(Nc1ccc(C2(O)CN(C(=O)OCc3ccccc3)C2)c(F)c1)OCc1ccccc1>>O=C(Nc1ccc(C2CN(C(=O)OCc3ccccc3)C2)c(F)c1)OCc1ccccc1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US05021443,Nc1cc(F)ccc1NCc1ccc(Cl)cc1.S=C=S>>Fc1ccc2c(c1)nc(S)n2Cc1ccc(Cl)cc1,,CCO,,,,test
US05624935,COC(=O)c1cc2ccccc2n1C>>Cn1c(CO)cc2ccccc21,,C1CCOC1,,O,[BH4-].[Li+],test
US20120108585A1,O=[N+]([O-])c1cccc2oc(-c3cccc(OC(F)(F)F)c3)nc12>>Nc1cccc2oc(-c3cccc(OC(F)(F)F)c3)nc12,[Pd],CO,,[H][H],,test
US20010016579A1,CN1CCNCC1.O=[N+]([O-])c1ccc2oc(S)nc2c1>>CN1CCN(c2nc3cc([N+](=O)[O-])ccc3o2)CC1,,Cc1ccccc1,,ClP(Cl)(Cl)(Cl)Cl,,test
US04428889,CC(C)CCBr.Oc1ccccc1>>CC(C)CCOc1ccccc1,,CCO,,C,C[O-].[Na+],test
US04168315,COC(=O)Cc1nc(-c2ccc(OC)cc2)c(-c2ccc(OC)cc2)s1>>COc1ccc(-c2nc(CCO)sc2-c2ccc(OC)cc2)cc1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20080113966A1,NN=C1NC[C@H](c2cccc(F)c2F)CC[C@H]1NC(=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1.O=C(Cl)C1CC1>>O=C(N[C@@H]1CC[C@@H](c2cccc(F)c2F)Cn2c(C3CC3)nnc21)N1CCC(n2c(=O)[nH]c3ncccc32)CC1,,ClCCl,,CCN(CC)CC,,test
US20110144105A1,C(=C(c1ccc2c(c1)OCCO2)c1cc2cccnc2[nH]1)C1CCCC1>>c1cnc2[nH]c(C(CC3CCCC3)c3ccc4c(c3)OCCO4)cc2c1,[Pd],CO,,,,test
US20100184805A1,COC(=O)NCCO[C@@H](c1cccc(Cl)c1)[C@@H]1CCCNC1.ClCCl.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COC(=O)NCCO[C@@H](c1cccc(Cl)c1)[C@@H]1CCCN(C(=O)Cl)C1,,ClCCl,,,,test
US20140005212A1,CS(=O)(=O)Cl.Nc1cc(Cl)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1>>CS(=O)(=O)Nc1cc(Cl)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US04933355,CCOC(=O)c1csc(NCc2ccccc2)n1>>OCc1csc(NCc2ccccc2)n1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130116289A1,CC(C)(C)[Si](C)(C)Cl.C[C@@H](NC(CO)c1ccc(C#N)cc1)C(=O)OC(C)(C)C>>C[C@@H](NC(CO[Si](C)(C)C(C)(C)C)c1ccc(C#N)cc1)C(=O)OC(C)(C)C,,ClCCl,,O,c1c[nH]cn1,test
US20160194302A1,CN(C)C1CCN(C(=O)CCc2nccn2CC(=O)O)CC1.OCC1CC1>>CN(C)C1CCN(C(=O)CCc2nccn2CC(=O)OCC2CC2)CC1,,ClC(Cl)Cl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04457931,CCOC(=O)C(C)Br.c1ccc(N2CCNCC2)nc1>>CCOC(=O)C(C)N1CCN(c2ccccn2)CC1,,CCO,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20030036557A1,CS(=O)(=O)c1ccc(N2CC(O)(C(F)(F)F)N=C2c2ccsc2)cc1>>CS(=O)(=O)c1ccc(-n2cc(C(F)(F)F)nc2-c2ccsc2)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20130237502A1,CS(=O)(=O)Cl.NCc1cn2ccc(Br)cc2n1>>CS(=O)(=O)NCc1cn2ccc(Br)cc2n1,,ClCCl,O,CCN(CC)CC,,test
US20110201650A1,COc1ccc(-n2nc(C3(O)CCC4(CC3)OCCO4)cc2-c2ccc(Cl)cc2)cc1>>COc1ccc(-n2nc(C3(O)CCC(=O)CC3)cc2-c2ccc(Cl)cc2)cc1,,C1CCOC1,Cl,[Na+].[OH-],,test
US05208247,CS(=O)(=O)Cl.NCc1ccccn1>>CS(=O)(=O)NCc1ccccn1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US06051570,CN1CCN(c2c(F)cc([N+](=O)[O-])c(N)c2F)CC1>>CN1CCN(c2c(F)cc(N)c(N)c2F)CC1,[Pd],CCO,,,,test
US20130344030A1,CC(C)[C@H](OC(=O)C1(/C=C/c2ccc3ccc([C@@H](C)NC(=O)OC(C)(C)C)nc3c2)COCCO1)C(=O)N[C@@H](C)C(=O)N1CCC[C@@H](C(=O)OCC(Cl)(Cl)Cl)N1>>CC(C)[C@H](OC(=O)C1(/C=C/c2ccc3ccc([C@@H](C)NC(=O)OC(C)(C)C)nc3c2)COCCO1)C(=O)N[C@@H](C)C(=O)N1CCC[C@@H](C(=O)O)N1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20050227972A1,CN(C)C=O.Cc1csc(Cl)n1.N#Cc1c(N)nc(S)c(C#N)c1-c1ccc(OCCO)cc1>>Cc1nc(CSc2nc(N)c(C#N)c(-c3ccc(OCCO)cc3)c2C#N)cs1,,CN(C)C=O,,Cl,O=C([O-])O.[Na+],test
US20140128390A1,COc1cccc([C@H](C)N=C=O)c1.C[C@@H]1CN(c2ncnc3[nH]c(-c4ccc(F)cc4)cc23)CCN1>>COc1cccc([C@H](C)NC(=O)N2CCN(c3ncnc4[nH]c(-c5ccc(F)cc5)cc34)C[C@H]2C)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20160083386A1,Clc1ccc2c(n1)N[C@H]1CCN2C1.O=C([O-])N(c1ccc(Cl)cc1)c1ccc(F)cn1>>O=C(Nc1ccc(F)cn1)N1c2nc(Cl)ccc2N2CC[C@H]1C2,CN(C)c1ccncc1,CCOC(C)=O,CN(C)C=O,,,test
US20110053910A1,COC[C@H](C)Oc1cc(O)cc(C(=O)Nc2ccn(C)n2)c1.O=C1NCCCc2nc(Cl)sc21>>COC[C@H](C)Oc1cc(Oc2nc3c(s2)C(=O)NCCC3)cc(C(=O)Nc2ccn(C)n2)c1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20070161622A1,COCCCOc1cc(C[C@@H](C[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CN)C(C)C)ccc1OC.O=C(Cl)c1ccccc1>>COCCCOc1cc(C[C@@H](C[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CNC(=O)c2ccccc2)C(C)C)ccc1OC,,O,,CCN(CC)CC,ClCCl,test
US04167638,C=Cc1ccc2cc(OC)cc([N+](=O)[O-])c2n1>>CCc1ccc2cc(OC)cc(N)c2n1,[Ni],Cc1ccccc1,,NN,O,test
US20160222005A1,CC(C)(C)OC(=O)N1CCC(Oc2ccc3nc(-c4ccc(OCc5ccccc5)cc4)[nH]c3n2)CC1>>c1ccc(COc2ccc(-c3nc4ccc(OC5CCNCC5)nc4[nH]3)cc2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110046000A1,CC1=CCN2C3=CC=C(CNC(=O)OC(C)(C)C)[C+]=C3C(C)(C)C2=C1.COC(OC)N(C)C.[O-][Cl+3]([O-])([O-])[O-]>>CN(C)C=CC1=CCN2C3=CC=C(CNC(=O)OC(C)(C)C)[C+]=C3C(C)(C)C2=C1.[O-][Cl+3]([O-])([O-])[O-],,CN(C)C=O,,C1CCC2=NCCCN2CC1,,test
US20030064991A1,C1CCNC1.Cc1[nH]c2ccc(CCOS(C)(=O)=O)cc2c1C(=O)OC(C)c1ccc(F)cc1>>Cc1[nH]c2ccc(CCN3CCCC3)cc2c1C(=O)OC(C)c1ccc(F)cc1,,C1COCCO1,,,,test
US04777165,C=C1C[C@@H]2C(=CC[C@@]3(C)[C@H]2C[C@H](C)[C@]3(O)C(C)=O)[C@@]2(C)CCC(=O)C=C12.CC(=O)O>>C=C1C[C@@H]2C(=CC[C@@]3(C)[C@H]2C[C@H](C)[C@]3(OC(C)=O)C(C)=O)[C@@]2(C)CCC(=O)C=C12,,CC(=O)O,,O=C(OC(=O)C(F)(F)F)C(F)(F)F,,test
US05677306,Cc1cccc2c1CC(n1ccnc1C(N)=O)C2=O.Cl>>Cc1cccc2c1Cc1c-2[nH]c(=O)c2nccn12.Cl,,CO,,,,test
US20060063746A1,CCNC(=O)O[C@]1(C(=O)COC(C)=O)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O[Si](C)(C)C)C[C@@]21C>>CCNC(=O)O[C@]1(C(=O)CO)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C,,CO,ClC(Cl)Cl,Cl,,test
US20130210844A1,COC(=O)c1cc(CNC(=O)OC(C)(C)C)ccc1Cl.Cl>>COC(=O)c1cc(CN)ccc1Cl.Cl,,CCOC(C)=O,,,,test
US20100216860A1,CN(C)C(=O)CCl.COC(=O)c1ccc(O)c(OC)c1>>COC(=O)c1ccc(OCC(=O)N(C)C)c(OC)c1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20050043334A1,Cc1cc(Nc2ncnc3ccc(C=O)cc23)ccc1Oc1ccccc1.NN>>Cc1cc(Nc2ncnc3ccc(C=NN)cc23)ccc1Oc1ccccc1,,CC(C)O,,ClCCl,,test
US20050250729A1,CCCCCNS(=O)(=O)c1ccc(N)cc1.O=C(Cl)OC(Cl)(Cl)Cl>>CCCCCNS(=O)(=O)c1ccc(N=C=O)cc1,,CC#N,,,,test
US20100004233A1,NCc1cccc(N)c1F.O=C(O)c1ccc(Oc2ncccn2)cc1C(=O)O>>Nc1cccc(CN2C(=O)c3ccc(Oc4ncccn4)cc3C2=O)c1F,,CCOC(C)=O,CN(C)C=O,O,c1c[nH]cn1,test
US06391874B1,Brc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1.CCCC[Sn](CCCC)(CCCC)c1ccco1>>c1ccc(COc2ccc(Nc3ncnc4ccc(-c5ccco5)cc34)cc2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,,,test
US20110118245A1,CC(C)(C)c1cc(NC(=O)Nc2cccc(Oc3ncnc4ccc(I)cc34)c2)no1.O=Cc1ccc(B(O)O)o1>>CC(C)(C)c1cc(NC(=O)Nc2cccc(Oc3ncnc4ccc(-c5ccc(C=O)o5)cc34)c2)no1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCO,COCCOC,O=C([O-])[O-].[Na+].[Na+],,test
US20080255122A1,COCCN1C(=O)C(O)=C(c2ccccc2)S1(=O)=O.O=C(Cl)C(=O)Cl>>COCCN1C(=O)C(Cl)=C(c2ccccc2)S1(=O)=O,,ClCCl,,,,test
US20090131461A1,COc1cc2c(Oc3ccc(N)cc3)ccnc2cc1OCc1ccccc1.O=C=Nc1ccc(C(F)(F)F)cc1>>COc1cc2c(Oc3ccc(NC(=O)Nc4ccc(C(F)(F)F)cc4)cc3)ccnc2cc1OCc1ccccc1,,ClCCl,,,,test
US20070149506A1,CN(C)C=O.Cc1c(Br)c(C(F)F)nn1C1CCCCO1>>Cc1c(C=O)c(C(F)F)nn1C1CCCCO1,,CCCCCC,,C1CCOC1,[Li]CCCC,test
US20100190775A1,CCNc1ncc2c(n1)N1CCC[C@H]1CN(c1cccc([N+]3([O-])CCN(C(=O)OC(C)(C)C)CC3)c1)C2=O>>CCNc1ncc2c(n1)N1CCC[C@H]1CN(c1cccc(N3CCN(C(=O)OC(C)(C)C)CC3)c1)C2=O,[Pd],CCO,,[H][H],,test
US06476053B1,CCCCCCCCCN1C(=O)C=CC1=O.CCCCN(CCN)CCCC>>CCCCCCCCCN1C(=O)CC(NCCN(CCCC)CCCC)C1=O,,CC#N,CCOC(C)=O,CCN(CC)CC,Cl,test
US20120165318A1,COC(=O)c1ccc2nc(-c3ccccc3)c(N3CCOCC3C)nc2c1>>CC1COCCN1c1nc2cc(C(=O)O)ccc2nc1-c1ccccc1,,CO,O,[Na+].[OH-],,test
US20060025438A1,C1CCC2=NCCCN2CC1.Cc1ccc(S(=O)(=O)[O-])cc1>>C1=Cc2ccccc2C1,,CS(C)=O,,O,,test
US05712267,C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(S[C@H]3C[C@@H](C(=O)N4CCN(C(=O)OCc5ccc([N+](=O)[O-])cc5)[C@H](C)C4)N(C(=O)OCc4ccc([N+](=O)[O-])cc4)C3)[C@H](C)[C@H]12.Cl>>C[C@@H]1CN(C(=O)[C@@H]2C[C@H](SC3=C(C(=O)O)N4C(=O)[C@H]([C@@H](C)O)[C@H]4[C@H]3C)CN2)CCN1.Cl,,C1CCOC1,O,,,test
US20130281392A1,Nc1cc(Oc2ccc(C(F)(F)F)cc2Cl)c(Cl)cc1[N+](=O)[O-]>>Nc1cc(Cl)c(Oc2ccc(C(F)(F)F)cc2Cl)cc1N,[Zn],CCO,,Cl,,test
US20140018319A1,COC(=O)c1cc(Br)c(O)c([N+](=O)[O-])c1.O=C(Cl)C(=O)Cl>>COC(=O)c1cc(Br)c(Cl)c([N+](=O)[O-])c1,,CCOC(C)=O,CN(C)C=O,,,test
US20030119022A1,C1CCOC1.COc1ccc2c(ccn2S(=O)(=O)c2ccccc2)c1>>COc1ccc2c(c1)cc(C=O)n2S(=O)(=O)c1ccccc1,,CCCCCC,,[Li]CCCC,[Cl-].[NH4+],test
US05401851,O=S(=O)(c1ccc(C(OC(c2ccccc2)c2ccc(S(=O)(=O)N3CCCC3)cc2)c2ccccc2)cc1)N1CCCC1>>O=S(=O)(c1ccc(O)cc1)N1CCCC1,[Pd],,,CCO,,test
US20120232056A1,COC(=O)c1ccc2nc(-c3occc3-c3ccccc3)c(N(C)C(C)C)nc2c1>>CC(C)N(C)c1nc2cc(C(=O)O)ccc2nc1-c1occc1-c1ccccc1,,CO,O,[Na+].[OH-],,test
US05493030,CC(C)(C)[Si](C)(C)Cl.COC(=O)CC/C(C)=C/Cc1c(O)c2c(c(C)c1OC)COC2=O>>COC(=O)CC/C(C)=C/Cc1c(OC)c(C)c2c(c1O[Si](C)(C)C(C)(C)C)C(=O)OC2,,CN(C)C=O,,O,c1c[nH]cn1,test
US20030199520A1,BrCc1ccccc1.COc1ccc(S(=O)(=O)N[C@@H](C(=O)O)C(C)C)cc1>>COc1ccc(S(=O)(=O)N[C@@H](C(=O)OCc2ccccc2)C(C)C)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20080153850A1,COC(=O)c1ccccc1Br.Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1C(=O)NCC12CC3CC(CC(C3)C1)C2>>Cc1ccc(-c2ccccc2C(=O)O)cc1C(=O)NCC12CC3CC(CC(C3)C1)C2,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1CCOC1,O,[Na+].[OH-],,test
US07259159B2,CCOC(=O)CCCn1cnc2c(NC[C@H](NC(=O)OCc3ccccc3)C(=O)OC(C)(C)C)ncnc21.NC1=NCCCN1>>CC(C)(C)OC(=O)[C@H](CNc1ncnc2c1ncn2CCCC(=O)NC1=NCCCN1)NC(=O)OCc1ccccc1,,CN(C)C=O,,,,test
US20030008872A1,COC(=O)c1c(-c2cccc(F)c2)nn2nc(OC)ccc12>>COc1ccc2c(C(=O)O)c(-c3cccc(F)c3)nn2n1,,CCO,,Cl,[Na+].[OH-],test
US20090149448A1,COc1ccc(C(C)C)cc1CN1CCNCC1.O=S(=O)(Cl)c1ccccc1>>COc1ccc(C(C)C)cc1CN1CCN(S(=O)(=O)c2ccccc2)CC1,,ClCCl,,CCN(CC)CC,O,test
US20100130559A1,C#CC(=O)OCC.Oc1ccc(I)cc1>>CCOC(=O)C#Cc1ccc(O)cc1,O=[Cu-],CN(C)C=O,,,,test
US20030130389A1,CO[Si](C)(OC)c1ccc(-c2ccc([Si](C)(OC)OC)cc2)cc1>>C[Si](O)(O)c1ccc(-c2ccc([Si](C)(O)O)cc2)cc1,,CCOCC,,CC(=O)O,,test
US20140206681A1,Cc1cc(Br)ccc1C(=O)O.Nc1cc(C(F)(F)F)ccn1>>Cc1cc(Br)ccc1C(=O)Nc1cc(C(F)(F)F)ccn1,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20050014942A1,CCOC(=O)Cl.Nc1ccc(Br)cc1I>>CCOC(=O)Nc1ccc(Br)cc1I,,c1ccncc1,,O,,test
US20130190249A1,O=C(OCc1ccccc1)[C@@H]1CNC(=O)N1C(=O)OCc1ccccc1>>CN1C[C@@H](C(=O)O)NC1=O,[Pd],,,CO,,test
US20140378474A1,NCc1cccc(Cl)c1.O=C(O)c1cnn(Cc2ccc(Cn3cccn3)cc2)c1>>O=C(NCc1cccc(Cl)c1)c1cnn(Cc2ccc(Cn3cccn3)cc2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US06066657,COc1ccc(Br)c2cc(COC3CCN(C(=O)OC(C)(C)C)CC3)oc12>>COc1ccc(Br)c2cc(COC3CCNCC3)oc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090221684A1,CC(C)(C)OC(=O)NCCCC[C@H](N)C(=O)O.CC(C)(C)OC(=O)NCCCC[C@H](N)C(=O)O.CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OC(C)(C)C)C(=O)O.N[C@@H](CCC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(=O)OCc1ccccc1)C(=O)O>>NCCCC[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(=O)OCc1ccccc1)C(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US04755512,COC(=O)CC(C)=O.O=Cc1cccc([N+](=O)[O-])c1>>COC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(C)=O,,O,c1ccccc1,C1CCNCC1,CC(=O)O,test
US20070060607A1,CCOC(=O)c1cnc(Cl)c2c(COc3cccc(C(=O)OC(C)(C)C)c3)csc12.N>>CCOC(=O)c1cnc(N)c2c(COc3cccc(C(=O)OC(C)(C)C)c3)csc12,,C1COCCO1,,,,test
US20160194315A1,COC(=O)c1ccnc2cc(COc3ccc(C(F)(F)F)cc3)[nH]c12>>O=C(O)c1ccnc2cc(COc3ccc(C(F)(F)F)cc3)[nH]c12,,CC#N,O,,,test
US20040236111A1,COc1ccc(S(=O)(=O)Cl)cc1.O=C(O)C1COCCN1>>COc1ccc(S(=O)(=O)N2CCOCC2C(=O)O)cc1,,ClCCl,,CCN(CC)CC,,test
US20160000760A1,CC1(C)OB(c2ccc(NC(=O)CCCBr)cc2)OC1(C)C>>CC1(C)OB(c2ccc(N3CCCC3=O)cc2)OC1(C)C,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20090142297A1,CCCN=C=O.NCc1ccc2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2=O>>CCCNC(=O)NCc1ccc2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2=O,,C1CCOC1,,CCN(C(C)C)C(C)C,Cl,test
US20090186898A1,C1CCNC1.Cc1c(N)cccc1B1OC(C)(C)C(C)(C)O1.O=C(Cl)Cl>>Cc1c(NC(=O)N2CCCC2)cccc1B1OC(C)(C)C(C)(C)O1,,Cc1ccccc1,ClCCl,CCN(C(C)C)C(C)C,,test
US05604213,CC(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CC=C(OS(=O)(=O)C(F)(F)F)[C@@]4(C)CC[C@@H]32)C1.CCB(CC)c1cccnc1>>CC(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CC=C(c5cccnc5)[C@@]4(C)CC[C@@H]32)C1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US06372764B1,C1COCCN1.O=CC1CN(C(=O)c2cccc3ccccc23)CC1CN1CCC(c2ccc(F)cc2)CC1>>O=C(c1cccc2ccccc12)N1CC(CN2CCOCC2)C(CN2CCC(c3ccc(F)cc3)CC2)C1,,CC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130079303A1,COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(CN4CCN(C(=O)OC(C)(C)C)C[C@H]4C)cnc3F)n2)cc1.CS(=O)(=O)Cl>>COc1ccc(CN(Cc2ccc(OC)cc2)c2nc(C)nc(-c3cc(CN4CCN(S(C)(=O)=O)C[C@H]4C)cnc3F)n2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US03935182,CN(CCCNC=O)CCCNC=O.COc1ccc([N+](=O)[O-])cc1CCl>>COc1ccc([N+](=O)[O-])cc1C[N+](C)(CCCNC=O)CCCNC=O.[Cl-],,O,,,,test
US20030199478A1,COC(=O)C(C(=O)OC)c1ccc(-c2cccc(OC)c2)cc1[N+](=O)[O-]>>COc1cccc(-c2ccc(CC(=O)O)c([N+](=O)[O-])c2)c1,,Cl,,,,test
US20080318975A1,COC(=O)Cc1c(Cl)ccc2ncc(CN(C)C)cc12.N>>CN(C)Cc1cnc2ccc(Cl)c(CC(N)=O)c2c1,,CO,,,,test
US20110021489A1,CCNCCO.O=C(N1CCOCC1)N1CC(c2ccc(C(F)(F)F)cc2)CC(c2nc(Cl)no2)C1>>CCN(CCO)c1noc(C2CC(c3ccc(C(F)(F)F)cc3)CN(C(=O)N3CCOCC3)C2)n1,,CCO,,,,test
US20080104772A1,C=CCBr.COc1cc(C=O)ccc1O>>C=CCOc1ccc(C=O)cc1OC,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US03933906,CC(=O)Nc1ccc(Nc2c(N)cc(C(=O)O)cc2S(N)(=O)=O)cc1.CC=CCBr>>CC=CCNc1cc(C(=O)O)cc(S(N)(=O)=O)c1Nc1ccc(NC(C)=O)cc1,,O,,[Na+].[OH-],,test
US20090291079A1,CCCC[Sn](CCCC)(CCCC)C1=CCOCC1.O=[N+]([O-])c1ccc(-c2nc(Cl)nc(N3C4CCC3COC4)n2)cc1>>O=[N+]([O-])c1ccc(-c2nc(C3=CCOCC3)nc(N3C4CCC3COC4)n2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,,,test
US04639267,COc1c(C)cccc1C.O=C1CCC(=O)O1>>COc1c(C)cc(C(=O)CCC(=O)O)cc1C,,ClCCCl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US04758501,CC(=O)c1ccc(O)cc1.CCCCBr>>CCCCOCC(=O)c1ccccc1,,CC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20160207885A1,CCOC(=O)C1CCN(c2ccncn2)CC1>>OCC1CCN(c2ccncn2)CC1,,CO,ClCCl,[BH4-].[Na+],,test
US20030135053A1,BrBr.Cc1ccc2c(c1)SCCC2(C)C>>Cc1cc2c(cc1Br)C(C)(C)CCS2,[Fe],ClCCl,,O=C([O-])O.[Na+],,test
US20160168139A1,CS(=O)(=O)Cl.Cc1cnc(C(=O)CO)cn1>>Cc1cnc(C(=O)COS(C)(=O)=O)cn1,,ClCCl,,CCN(CC)CC,[Cl-].[NH4+],test
US05969146,CCOC(=O)Nc1csc2cc(O)ccc12.FC(F)(F)CCCBr>>CCOC(=O)Nc1csc2cc(OCCCC(F)(F)F)ccc12,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20090221555A1,O=C1CCOc2ccc(F)cc21.[N-]=[N+]=[N-]>>O=C1NCCOc2ccc(F)cc21,,O=S(=O)(O)O,,O,,test
US08101588B2,CCN(CC)CC.C[C@H](NC(=O)OC(C)(C)C)C(=O)O.On1nnc2ccccc21>>CON(C)C(=O)[C@H](C)NC(=O)OC(C)(C)C,,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20080194668A1,CCCCc1ccc(-c2ccc(N)c([N+](=O)[O-])c2)cc1>>CCCCc1ccc(-c2ccc(N)c(N)c2)cc1,[Pd],CCOC(C)=O,CO,,,test
US05763439,CC1CCOC(c2c(Cl)cnn(C(C)(C)C)c2=O)O1.NCc1ccncc1>>CC1CCOC(c2c(NCc3ccncc3)cnn(C(C)(C)C)c2=O)O1,,CCO,,,,test
US06376491B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCOC(=O)c1oc2cccc(OCCCNC(C)(C)C)c2c1C>>CCOC(=O)c1oc2cccc(OCCCN(C(=O)OC(C)(C)C)C(C)(C)C)c2c1C,,ClCCl,,,,test
US07612060B2,C[C@H](c1ccc(CO)cc1)n1cc(C[C@@H]2C(=O)NC=CN2S(=O)(=O)c2ccc(Cl)c(Cl)c2)nn1>>C[C@H](c1ccc(C=O)cc1)n1cc(C[C@@H]2C(=O)NC=CN2S(=O)(=O)c2ccc(Cl)c(Cl)c2)nn1,O=[Mn]=O,ClCCl,,CO,,test
US20090156610A1,Cc1ccc(S(=O)(=O)OC2CCN(C(=O)OC(C)(C)C)CC2)cc1.O=Cc1c(O)ccc(Br)c1F>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(Br)c(F)c2C=O)CC1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20040127574A1,Cc1ccc(Br)c2c1CCCCC2O>>Cc1ccc(Br)c2c1CCCC=C2,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20050159598A1,CC(O)=S.CCOC(=O)C(Cl)C(C)=O.N#Cc1ccc(C(F)(F)F)cc1F>>CCOC(=O)c1sc(-c2ccc(C(F)(F)F)cc2F)nc1C,,Cc1ccccc1,O,CCOCC,FB(F)F,test
US20040058964A1,COC(=O)c1ccc(Cn2ccc(OCc3ccc(F)cc3F)c(Cl)c2=O)cc1.N>>NC(=O)c1ccc(Cn2ccc(OCc3ccc(F)cc3F)c(Cl)c2=O)cc1,,CO,,,,test
US04022761,CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O.CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)O.CCCCOC(=O)N[C@@H](COCc1ccccc1)C(=O)O.CO>>COC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)[C@H](COCc1ccccc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C,,CCN(CC)CC,CO,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20040077726A1,COC(=O)C=Cc1cccc(S(=O)(=O)Cl)c1.NCc1cccc2ccccc12>>COC(=O)C=Cc1cccc(S(=O)(=O)NCc2cccc3ccccc23)c1,,C1COCCO1,O,O=C([O-])O.[Na+],,test
US20140100231A1,COc1ccc(Cn2cnc(C(C)(F)F)c(Br)c2=O)cc1.N#Cc1cc(O)cc(Cl)c1>>COc1ccc(Cn2cnc(C(C)(F)F)c(Oc3cc(Cl)cc(C#N)c3)c2=O)cc1,,CN1CCCC1=O,O,O=C([O-])[O-].[K+].[K+],,test
US20150291563A1,CC(C)(C)OC(=O)N1CCCN(c2ccc(C3CC(C(O)(C(F)(F)F)C(F)(F)F)=NN3c3ccc(F)cc3F)cc2)CC1.Cl>>Cl.OC(C1=NN(c2ccc(F)cc2F)C(c2ccc(N3CCCNCC3)cc2)C1)(C(F)(F)F)C(F)(F)F,,CCOC(C)=O,,,,test
US20140141034A1,CCOC(=O)NN.NCCCCNC(=O)OCc1ccccc1.O=C(Cl)Oc1ccc([N+](=O)[O-])cc1>>CCOC(=O)NNC(=O)NCCCCNC(=O)OCc1ccccc1,,C1CCOC1,O,CCN(CC)CC,Cl,test
US04615726,CCN=C=O.CCOC(=O)c1ccccc1C1=NC(=O)C(C)(C(C)C)N1>>CCNC(=O)N1C(c2ccccc2C(=O)OCC)=NC(=O)C1(C)C(C)C,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20080207655A1,CC1(C)OCC(N)CO1.N=C(N)n1cccn1>>CC1(C)OCC(NC(=N)N)CO1,,C1CCOC1,,,,test
US20070197393A1,CS(=O)(=O)c1ccc(Br)c2c1C1=NOCC1C2.Cn1nccc1O.[C]=O>>Cn1ncc(C(=O)c2ccc(S(C)(=O)=O)c3c2CC2CON=C32)c1O,,C1COCCO1,,CCN(CC)CC,O=C([O-])[O-].[K+].[K+],test
US20120225867A1,C[C@@H](Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1coc(CCl)n1.c1c[nH]cn1>>C[C@@H](Cn1ccc(-c2ccc(C#N)c(Cl)c2)n1)NC(=O)c1coc(Cn2ccnc2)n1,,CN(C)C=O,,[H-].[Na+],,test
US20040010022A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1OC(N)=NC1=O>>CC1OC(NC(=O)OC(C)(C)C)=NC1=O,CN(C)c1ccncc1,CN(C)C=O,,CCN(CC)CC,,test
US04916149,NN.NS(=O)(=O)c1ccc(Cl)c([N+](=O)[O-])c1>>NNc1ccc(S(N)(=O)=O)cc1[N+](=O)[O-],,CCO,,O,,test
US04792570,Cc1ccc(S(=O)(=O)OCCCCCCCl)cc1.Oc1ccc(-c2ccccc2)cc1>>ClCCCCCCOc1ccc(-c2ccccc2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20070213341A1,C[Si](C)(C)C#Cc1ccc(OCCO)c(C2NC(=O)CC(c3cccc(Cl)c3)C23C(=O)Nc2cc(Cl)ccc23)c1F>>C#Cc1ccc(OCCO)c(C2NC(=O)CC(c3cccc(Cl)c3)C23C(=O)Nc2cc(Cl)ccc23)c1F,,CO,,[F-].[K+],,test
US04374138,CCOC(=O)c1cc2cc([N+](=O)[O-])ccc2[nH]c1=O>>O=C(O)c1cc2cc([N+](=O)[O-])ccc2[nH]c1=O,,Cl,,[Na+].[OH-],,test
US07265227B2,COC(=O)CCCBr.Clc1ccc(OC2CCNCC2)cc1Cl>>COC(=O)CCCN1CCC(Oc2ccc(Cl)c(Cl)c2)CC1,,CC(C)=O,,[I-].[K+],O=C([O-])O.[Na+],test
US06562828B1,CCOC(C)=N.COCCn1c(COc2ccc(OC3CCNC3)cc2)nc2cc(C(=N)N)ccc21.Cl.Cl>>COCCn1c(COc2ccc(OC3CCN(C(C)=N)C3)cc2)nc2cc(C(=N)N)ccc21.Cl.Cl,,C1CCOC1,O,Cl,O=C([O-])O.[Na+],test
US20050234071A1,ClCCCl.O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1>>ClCCCl.O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1,,ClCCCl,,,,test
US20020161240A1,CC(C)(C)OC(=O)COc1cccc([C@H](O)CCc2cccnc2)c1.CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)O>>CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCc1cccnc1)c1cccc(OCC(=O)OC(C)(C)C)c1,CN(C)c1ccncc1,ClCCl,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20090124595A1,CC(C)(C)OCCON.Cc1c(Nc2ccc(I)cc2F)c(C(=O)O)c2n(c1=O)CCC2>>Cc1c(Nc2ccc(I)cc2F)c(C(=O)NOCCO)c2n(c1=O)CCC2,,CN(C)C=O,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20110021537A1,C[C@H](NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1)C(=O)OC(C)(C)C>>C[C@H](NC(=O)c1cc(OCC(=O)N2CCC[C@H]2C(=O)NC2CCC2)n(-c2ccccc2)n1)C(=O)O,,ClCCl,,O=C(O)C(F)(F)F,,test
US20010018525A1,O=C(NCCOc1c(Br)cc(C(=O)NCCCCCCCCc2ccccc2)cc1-c1cccc(C(F)(F)F)c1)NC(=O)C(Cl)(Cl)Cl>>CCCCCCCCCCCCNC(=O)c1cc(Br)c(OCCNC(N)=O)c(-c2cccc(C(F)(F)F)c2)c1,,CO,ClCCl,[Na+].[OH-],,test
US20100113509A1,Cc1cc(N2C3CCC2CC3)ncc1NC(=O)c1c[nH]c2cccc(C)c2c1=O.Cl>>Cc1cc(N2C3CCC2CC3)ncc1NC(=O)c1c[nH]c2cccc(C)c2c1=O.Cl,,CO,,CCOCC,,test
US20140275531A1,COc1nc(C)c(C=O)cc1-c1cccc(Cl)c1.COc1nc(C)c(CO)cc1-c1cccc(Cl)c1>>COc1nc(C)c(CCl)cc1-c1cccc(Cl)c1,,CO,,[BH4-].[Na+],,test
US06166219,COC(=O)C=Cc1ccc2nc(C)n(Cc3ccccc3Cl)c2c1>>Cc1nc2ccc(C=CC(=O)O)cc2n1Cc1ccccc1Cl,,CCO,,Cl,[Na+].[OH-],test
US20160102071A1,CC#C[C@@H](CC(=O)OCC)c1ccc(OCc2ccc3scc(-c4cnc(OCCOC)cc4C)c3c2)cc1>>CC#C[C@@H](CC(=O)O)c1ccc(OCc2ccc3scc(-c4cnc(OCCOC)cc4C)c3c2)cc1,,CCO,,Cl,[Li+].[OH-],test
US20040180911A1,CCNCC.NC[C@@H]1C[C@@H](n2cc(-c3cccc(OCc4ccccc4)c3)c3c(N)ncnc32)C1.O=C(Cl)OCCBr>>CCN(CC)CCOC(=O)NC[C@@H]1C[C@@H](n2cc(-c3cccc(OCc4ccccc4)c3)c3c(N)ncnc32)C1,,ClCCl,,CCN(CC)CC,,test
US04200748,CCN(CC)CC.CN(C)C=O.O=[N+]([O-])c1ccc2nc(Cl)c(Cl)nc2c1>>O=[N+]([O-])c1ccc2nc3c(nc2c1)OCC1CCCN31,,O,,,,test
US20100174094A1,CN(C)N.O=C(C=CCl)C(Cl)Cl>>Cn1ccc(C(Cl)Cl)n1,,COC(C)(C)C,,,,test
US20140371199A1,C1COCCN1.N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)O)cc4)cn23)cc1>>N#Cc1ccc(-c2cnc3ccc(-c4ccc(C(=O)N5CCOCC5)cc4)cn23)cc1,,CN(C)C=O,O,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05688803,NC(N)=O.Nc1cc([N+](=O)[O-])c(Cl)cc1C(=O)O>>O=c1[nH]c(=O)c2cc(Cl)c([N+](=O)[O-])cc2[nH]1,,O,,,,test
US20110098429A1,CC(C)(C)c1cccc(C(=O)c2cccc(-c3ccccn3)c2)c1OCc1ccccc1.[Li]c1ccccc1>>CC(C)(C)c1cccc(C(O)(c2ccccc2)c2cccc(-c3ccccn3)c2)c1OCc1ccccc1,,C1CCOC1,,[Cl-].[NH4+],,test
US20160102059A1,COc1cc([N+](=O)[O-])ccc1S.OCCCBr>>COc1cc([N+](=O)[O-])ccc1SCCCO,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20040180934A1,CC(O)c1cc(F)cc2c1c(Sc1ccc(Cl)cc1)c1n2CCC1CC(=O)O>>CCc1cc(F)cc2c1c(Sc1ccc(Cl)cc1)c1n2CCC1CC(=O)O,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20090023789A1,CCOC(=O)/N=c1\sn(C(C)(C)C)cc1Cc1ccco1>>CC(C)(C)n1cc(Cc2ccco2)c(=N)s1,,ClC(Cl)Cl,ClCCl,C[Si](C)(C)I,,test
US20140135332A1,CC(=O)OCC(Br)c1nc(-c2ccc(C(F)(F)F)cc2)c(Br)o1.NC(=O)c1c(F)ccc(O)c1F>>CC(=O)OCC(Oc1ccc(F)c(C(N)=O)c1F)c1nc(-c2ccc(C(F)(F)F)cc2)c(Br)o1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110269742A1,N#Cc1ccc(C(=O)N2CCC(c3nc4ccccc4[nH]3)CC2)cc1.NO>>N=C(NO)c1ccc(C(=O)N2CCC(c3nc4ccccc4[nH]3)CC2)cc1,,CCO,,,,test
US20060025474A1,CCC(CC)(c1ccc(C#CC(OCOC)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(OCCCCc2nnn[nH]2)c(C)c1>>CCC(CC)(c1ccc(C#CC(O)(C(F)(F)F)C(F)(F)F)c(C)c1)c1ccc(OCCCCc2nnn[nH]2)c(C)c1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20110172442A1,COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C=Cc1ccc(C(C)C)cc1>>CC(C)c1ccc(C=CC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)O)cc1,,CO,,[Na+].[OH-],,test
US20140045862A1,CCn1nccc1[C@H]1CCCC[C@@H]1Oc1ccc(S(=O)(=O)N(Cc2ccc(OC)cc2OC)c2ccncn2)c(F)c1>>CCn1nccc1[C@H]1CCCC[C@@H]1Oc1ccc(S(=O)(=O)Nc2ccncn2)c(F)c1,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20040009991A1,C/C(N)=C/C(=O)OCCC(c1ccccc1)c1ccccc1.CC(=O)C(=Cc1ccc(C)cc1C)C(=O)N1CCN(C(=O)OC(C)(C)C)CC1>>Cc1ccc(-c2c(C(=O)OCCC(c3ccccc3)c3ccccc3)c(C)nc(C)c2C(=O)N2CCNCC2)c(C)c1,,CC(C)O,,,,test
US05693827,CC(C)OC(=O)c1cc(N)ccc1Cl.CC1=C(C(=O)O)SCCO1>>CC1=C(C(=O)Nc2ccc(Cl)c(C(=O)OC(C)C)c2)SCCO1,,ClCCl,,CCN(CC)CC,O=S(Cl)Cl,test
US20110130445A1,CC(C)(C)OC(=O)CCc1ccc(Cl)c(N)c1.C[C@H]([C@H](C(=O)Cl)c1ccc(Cl)cc1)C(F)(F)F>>C[C@H]([C@H](C(=O)Nc1cc(CCC(=O)OC(C)(C)C)ccc1Cl)c1ccc(Cl)cc1)C(F)(F)F,,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,O,test
US20140221411A1,BrCc1ccccc1.O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cc(Cl)ccc1O>>O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cc(Cl)ccc1OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160083387A1,C=C1CC[C@H]2[C@H](CO)[C@@H]([C@@]3(C)CC[C@H](NC(=O)C(F)(F)F)C[C@@H]3CO)CC[C@]12C>>C=C1CC[C@H]2[C@H](CO)[C@@H]([C@@]3(C)CC[C@H](N)C[C@@H]3CO)CC[C@]12C,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20060211720A1,CN(C)C=O.Cn1cnc(-c2ccccc2)n1>>Cn1nc(-c2ccccc2)nc1C=O,,C1CCOC1,,O,[Li]CCCC,test
US20100056374A1,Fc1ccc(F)c2c(NCCc3ccc(Oc4cc(C(F)(F)F)ccn4)c(Br)c3)ncnc12.N#C[Cu]>>N#Cc1cc(CCNc2ncnc3c(F)ccc(F)c23)ccc1Oc1cc(C(F)(F)F)ccn1,,CN(C)C=O,,,,test
US04760182,ClCC1CO1.OCCc1ccc(O)cc1>>OCCc1ccc(OCC2CO2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080132546A1,CCNC(=O)Nc1ccc(B2OC(C)(C)C(C)(C)O2)cn1.CCOC(=O)c1sc(Cl)nc1C(=O)NC(C)C>>CCNC(=O)Nc1ccc(-c2nc(C(=O)NC(C)C)c(C(=O)OCC)s2)cn1,c1ccc([PH](c2ccccc2)(c2ccccc2)[Pd-4]([PH](c2ccccc2)(c2ccccc2)c2ccccc2)([PH](c2ccccc2)(c2ccccc2)c2ccccc2)[PH](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,CCOC(C)=O,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20130210768A1,CC(C)COC(=O)NCc1cccc(-c2ccc3c(n2)n(C)c(=O)n3CC(C)(C)C)c1.CI>>CC(C)COC(=O)NCCc1cccc(-c2ccc3c(n2)n(C)c(=O)n3CC(C)(C)C)c1,,C1CCOC1,,CO,[H-].[Na+],test
US06486190B1,C=O.CCc1c([N+](=O)[O-])cc(C)c(N)c1[N+](=O)[O-]>>CCc1c([N+](=O)[O-])cc(C)c(NC)c1[N+](=O)[O-],,O=S(=O)(O)O,,,,test
US20140288094A1,CCI.Fc1cncc(Br)c1>>CCc1c(F)cncc1Br,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20100105922A1,CCOC(=O)C[Zn]Br.O=C1CCCCC1>>CCOC(=O)CC1(O)CCCCC1,,C1CCOC1,,CCOC(C)=O,Cl,test
US06617325B1,CI.COC(=O)CC(C)(CCCN1CCC(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)CC1)c1ccccc1>>COC(=O)CC(C)(CCCN1CCC(N(C)C(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)CC1)c1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20030130213A1,FF.N#Cc1nccnc1N>>N#Cc1nc(F)cnc1N,,CC#N,,,,test
US20050137168A1,CCOC(C(=O)NCc1ccc(C#N)cc1[N+](=O)[O-])N1Cc2c(C)cccc2C1=O>>CCOC(C(=O)NCc1ccc(C#N)cc1N)N1Cc2c(C)cccc2C1=O,[Pd],CCOC(C)=O,,,,test
US04642313,COC(=O)c1ncoc1-c1ccoc1>>O=C(O)c1ncoc1-c1ccoc1,,CO,,[K+].[OH-],,test
US20110039718A1,COS(=O)(=O)OC.Cc1[nH]nc2cc([N+](=O)[O-])ccc12>>Cc1c2ccc([N+](=O)[O-])cc2nn1C,,CS(C)=O,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US04004907,O=[N+]([O-])c1ccc(SCCCc2ccccc2)cc1>>Nc1ccc(SCCCc2ccccc2)cc1,[Ni],CN(C)C=O,,,,test
US20100286115A1,COC(=O)c1cc(NCc2c(-c3ccc(F)cc3)noc2C)n[nH]1>>Cc1onc(-c2ccc(F)cc2)c1CNc1cc(C(=O)O)[nH]n1,,C1CCOC1,O,[Li+].[OH-],,test
US20150080393A1,C=C/C(=C\C=C/C)COC(=O)N1CC2(CCN(c3cc(O[C@H](c4ccc(/C=C/C(=O)OCC)cc4-n4ccc(C)n4)C(F)(F)F)nc(N)n3)CC2)C[C@H]1C(=O)O>>CCOC(=O)CCc1ccc([C@@H](Oc2cc(N3CCC4(CC3)CN[C@H](C(=O)O)C4)nc(N)n2)C(F)(F)F)c(-n2ccc(C)n2)c1,[Pd],CO,,,,test
US06160132,CCCCCCC[C@@H]1C[C@H](CSC(c2ccccc2)(c2ccccc2)c2ccccc2)OC1=O.O>>CCCCCCC[C@H](C[C@@H](O)CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O,,CO,O,Cl,[Na+].[OH-],test
US20090312314A1,CC(=O)O[C@H](C(=O)N(CCc1ccc(C(F)(F)F)cc1)c1cnc2ccccc2c1)c1ccccc1>>O=C([C@@H](O)c1ccccc1)N(CCc1ccc(C(F)(F)F)cc1)c1cnc2ccccc2c1,,C1CCOC1,O,[Li+].[OH-],,test
US20080262050A1,O=CNc1cc([N+](=O)[O-])ccc1OCc1ccccc1>>Nc1ccc(OCc2ccccc2)c(NC=O)c1,[Pt],CCO,,,,test
US03962307,CC(C)c1cc(O)c(C(C)C)c(Br)c1O.COCCl>>CC(C)c1c(O)c(CCl)c(C(C)C)c(O)c1Br,,S=C=S,,,,test
US06180627B2,CO.Cc1cc2[nH]ncc2cc1C#N>>CCc1cc2[nH]ncc2cc1CN,,C1CCOC1,O,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20120165333A1,CS(=O)(=O)OC1CCOCC1.Ic1cn[nH]c1>>Ic1cnn(C2CCOCC2)c1,,CN(C)C=O,,O,[H-].[Na+],test
US20100063091A1,COCCBr.COCCc1cc(O)cc(C(=O)OC)c1>>COCCOc1cc(CCOC)cc(C(=O)OC)c1,,CCOCC,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090186891A1,NNC(=O)c1ccc2nc(-c3c(Cl)cccc3Cl)[nH]c2c1.Nc1ccc(Cl)nc1.S=C(n1ccnc1)n1ccnc1>>Clc1ccc(Nc2nnc(-c3ccc4nc(-c5c(Cl)cccc5Cl)[nH]c4c3)o2)cn1,,CCOC(C)=O,CN(C)C=O,CCN=C=NCCCN(C)C,,test
US04710500,Brc1cccnc1.CN1CC=C(c2c[nH]c3ccc([N+](=O)[O-])cc23)CC1>>CN1CC=C(c2cn(-c3cccnc3)c3ccc([N+](=O)[O-])cc23)CC1,,[NH4+],[OH-],O=C([O-])[O-].[K+].[K+],,test
US20050256158A1,CC(=O)N(c1ccc(Cl)cc1)[C@@H]1C[C@H](C)N(C(=O)c2ccc(O)cc2)c2ccccc21.CCOC(=O)C(F)Br>>CCOC(=O)[C@H](F)Oc1ccc(C(=O)N2c3ccccc3[C@H](N(C(C)=O)c3ccc(Cl)cc3)CC2C)cc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06093732,CCOC(=O)c1cnc2cc(OC)c(OC)cc2c1O.NCc1ccc(Cl)cc1>>COc1cc2ncc(C(=O)NCc3ccc(Cl)cc3)c(O)c2cc1OC,,Cc1ccccc1,,,,test
US05110955,CC(=O)OC/C=C(\C)CCC1=C(C)C(=O)C(C)=C(C)C1=O>>CC(=O)OC/C=C(\C)CCc1c(C)c(O)c(C)c(C)c1O,,C1CCOC1,O,O=S([O-])S(=O)[O-].[Na+].[Na+],,test
US20160090387A1,CC(C)n1cnc2c(Cl)nc(Cl)nc21.NCc1cccnc1>>CC(C)n1cnc2c(NCc3cccnc3)nc(Cl)nc21,,CCCCO,,CCN(CC)CC,,test
US20020119992A1,CC(C)(C)OC(=O)N[C@@H](C(=O)N1CCC[C@H]1C(=O)NCc1cc(Cl)ccc1CC(N)C(F)(F)F)C1CCCCC1>>NC(Cc1ccc(Cl)cc1CNC(=O)[C@@H]1CCCN1C(=O)[C@H](N)C1CCCCC1)C(F)(F)F,,ClCCl,,O=C(O)C(F)(F)F,,test
US20120157482A1,BrBr.COc1cc([N+](=O)[O-])ccc1O>>COc1cc([N+](=O)[O-])cc(Br)c1O,,CC(=O)O,,O,,test
US20130345181A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Ic1cn[nH]c1>>CC(C)(C)OC(=O)n1cc(I)cn1,,C1CCOC1,,CCN(CC)CC,,test
US20130210806A1,CC(C)(C)OC(=O)NC(=S)NC(=O)OC(C)(C)C.FC(F)(F)c1c(CCc2ccccc2)cc2c3c1ccn3CCNC2>>CC(C)(C)OC(=O)/N=C(\NC(=O)OC(C)(C)C)C1Cn2ccc3c(C(F)(F)F)c(CCc4ccccc4)cc(c32)CN1,,CN(C)C=O,,CCN(CC)CC,CCOC(C)=O,test
US20050137201A1,CNCC(OC)OC.O=C(Cc1cccc(F)c1F)c1c[nH]c(C(=O)C(Cl)(Cl)Cl)c1>>COC(CN(C)C(=O)c1cc(C(=O)Cc2cccc(F)c2F)c[nH]1)OC,,CC#N,,,,test
US20090215759A1,C1CCNCC1.Cc1cc(Cl)nc(Cl)n1>>Cc1cc(N2CCCCC2)nc(Cl)n1,,C1CCOC1,,,,test
US20100105921A1,Cc1cc(N=O)cc(C)c1O.O=Cc1ccccc1>>Cc1cc(N(O)C(=O)c2ccccc2)cc(C)c1O,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20100105667A1,COc1cc(OC)c(Cl)c(-c2ccc(C(=O)Nc3ccc(CN4CCN(C)CC4)cn3)c3nccnc23)c1Cl.COc1cc(OC)c(Cl)c(-c2ccc(C(=O)O)c3ncccc23)c1Cl>>COc1cc(OC)c(Cl)c(-c2ccc(C(=O)Nc3ccc(CN4CCN(C)CC4)cn3)c3ncccc23)c1Cl,,CO,ClCCl,,,test
US20100010001A1,CCOc1ccc(C(N)=O)cc1OCC.O=C(CBr)c1ccncc1>>CCOc1ccc(-c2nc(-c3ccncc3)co2)cc1OCC,,CN(C)C=O,,Br,O=C([O-])O.[Na+],test
US20150368238A1,CN(C)C=O.Fc1ccc(OC2CCOC2)c(Br)c1>>O=Cc1cc(F)ccc1OC1CCOC1,,C1CCOC1,,CC(C)[Mg]Cl,,test
US20070244092A1,CC(C)(C)c1nc2cc(S(=O)(=O)n3cc(C(=O)O)cn3)ccc2n1CC1CCOCC1.CCN>>CCNC(=O)c1cnn(S(=O)(=O)c2ccc3c(c2)nc(C(C)(C)C)n3CC2CCOCC2)c1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20160024021A1,CCN1CCN(c2cccc(Nc3ncc(/C=C/c4cc(OC)cc(C(=O)NOC)c4)cn3)c2)CC1>>CCN1CCN(c2cccc(Nc3ncc(CCc4cc(OC)cc(C(=O)NOC)c4)cn3)c2)CC1,[Pd],CO,,,,test
US09156827B2,CC(C)(C)OC(=O)N1CCN(Cc2c(OCc3ccccc3)ccc3c2OCC3=O)CC1.O=Cc1c[nH]c2ccccc12>>CC(C)(C)OC(=O)N1CCN(Cc2c(OCc3ccccc3)ccc3c2O/C(=C\c2c[nH]c4ccccc24)C3=O)CC1,,CO,,C1CCNCC1,,test
US20070155716A1,NC(=O)c1cccn1N.O=C(Cl)c1cc(Cl)ccc1F>>NC(=O)c1cccn1NC(=O)c1cc(Cl)ccc1F,,CC#N,ClC(Cl)Cl,CCN(CC)CC,CO,test
US20010051631A1,CC(C)(C)OC(=O)N1CCC(CBr)CC1.Cc1nc2cccc3[nH]c(=O)c1n23>>Cc1nc2cccc3n(CC4CCN(C(=O)OC(C)(C)C)CC4)c(=O)c1n23,,CN(C)C=O,,O,[H-].[Na+],test
US20160068515A1,CC(C)(C)OC(=O)N1CCNCC1.CCc1cnc(Cl)nc1>>CCc1cnc(N2CCN(C(=O)OC(C)(C)C)CC2)nc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20040248951A1,CCOC(=O)CCl.CCOC=O.NC(=S)c1ccc(C(F)(F)F)cc1>>CCOC(=O)c1cnc(-c2ccc(C(F)(F)F)cc2)s1,,CCOCC,,C,C[O-].[Na+],test
US20130252944A1,CCC(O)c1nn(Cc2ccc(OC)cc2)cc1-c1nc(Nc2ncc(F)cn2)sc1CO>>CCC1OCc2sc(Nc3ncc(F)cn3)nc2-c2c[nH]nc21,,O=C(O)C(F)(F)F,,,,test
US20040157881A1,C#Cc1ccc(C(=O)OC)cc1.ON=C(Cl)c1ccccc1>>COC(=O)c1ccc(-c2cc(-c3ccccc3)no2)cc1,,C1CCOC1,,CCN(CC)CC,O,test
US20060167040A1,Fc1ccc(-c2nc3[nH]ncc3c(-c3ccc(F)cc3)c2-c2ccncc2)cc1.O=C1CCC(=O)N1Cl>>Fc1ccc(-c2nc3[nH]nc(Cl)c3c(-c3ccc(F)cc3)c2-c2ccncc2)cc1,,CN(C)C=O,,,,test
US20100168094A1,COc1cc(N2C(=O)c3ccccc3C2=O)ccc1C(C)(C)C>>COc1cc(N)ccc1C(C)(C)C,,CCO,,NN,,test
US03971789,Clc1ccc2c(Cl)ccnc2c1.Nc1ccc(I)cc1C(=O)O>>O=C(O)c1cc(I)ccc1Nc1ccnc2cc(Cl)ccc12,,Cl,,,,test
US20040260088A1,CN.N#Cc1ccc(Cl)cc1Oc1ccc(F)c(CCl)c1.O=C(O)/C=C/C(=O)O>>CNCc1cc(Oc2cc(Cl)ccc2C#N)ccc1F.O=C(O)/C=C/C(=O)O,,CCO,CO,,,test
US20070010670A1,COc1c(F)cc(C(=O)Cl)cc1F.c1ccc2c(c1)NCCO2>>COc1c(F)cc(C(=O)N2CCOc3ccccc32)cc1F,,ClC(Cl)Cl,,CCN(CC)CC,,test
US20020161237A1,CC(N)=S.CCOC(=O)CC(=O)C(C)(C)Cl>>CCOC(=O)c1sc(C)nc1C(C)C,,CCO,,,,test
US05741926,N#Cc1ccc(N)cc1.O=C(Br)CBr>>N#Cc1ccc(NC(=O)CBr)cc1,,C1COCCO1,,CN(C)C=O,,test
US20040122063A1,CC(C)(C)OC(=O)N[C@@H]1CCC(=O)C[C@@H]1NC(=O)OC(C)(C)C.CON>>CON=C1CC[C@@H](NC(=O)OC(C)(C)C)[C@@H](NC(=O)OC(C)(C)C)C1,,CO,,Cl,c1ccncc1,test
US20010036653A1,CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@@H](O)[C@@H](NC(=O)OC(C)(C)C)C1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@@H](OS(=O)(=O)C(F)(F)F)[C@@H](NC(=O)OC(C)(C)C)C1,,ClCCl,,c1ccncc1,,test
US20040038993A1,CO.COC(=O)c1cc2[nH]c(-c3ccc(OCc4ccccc4)cc3)c(C3CCCCC3)c(=O)n2n1>>COC(=O)c1cc2nc(-c3ccc(OCc4ccccc4)cc3)c(C3CCCCC3)c(OC)n2n1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20110172245A1,Cn1c(NC(=O)C2CC2)nc2ccc(Oc3cccc(N)c3)cc21.N#CC1(c2cccc(C(=O)O)c2)CC1>>Cn1c(NC(=O)C2CC2)nc2ccc(Oc3cccc(NC(=O)c4cccc(C5(C#N)CC5)c4)c3)cc21,CN(C)c1ccncc1,c1ccncc1,,CCN=C=NCCCN(C)C,Cl,test
US20120009274A1,Cc1cccc(C(=O)NN)c1.O=Cc1cccc(Cl)c1O>>Cc1cccc(C(=O)NN=Cc2cccc(Cl)c2O)c1,,CCO,,,,test
US05280032,Cc1ccc(S(=O)(=O)Cl)cc1.OCCOCC(O)c1ccc(OCc2ccccc2)cc1>>Cc1ccc(S(=O)(=O)OCCOCC(O)c2ccc(OCc3ccccc3)cc2)cc1,,c1ccncc1,,CCOCC,Cl,test
US20070167486A1,COC(=O)CC1=CCCN(Cc2ccc(OC)cc2OC)C1=O>>COC(=O)CC1CCCN(Cc2ccc(OC)cc2OC)C1=O,[Pd],CO,,,,test
US20080160028A1,CCO.Cc1cc(-c2ccccc2)nc2oc3c(Cl)nc(Cl)nc3c12>>CCOc1nc(Cl)nc2c1oc1nc(-c3ccccc3)cc(C)c12,,CCO,,C,C[O-].[Na+],test
US20160264517A1,CCCCCC[C@@H](C)OC(=O)c1ccc(-c2ccc(O[C@@H]3CCOC3)cc2)cc1>>O=C(O)c1ccc(-c2ccc(O[C@@H]3CCOC3)cc2)cc1,,C1CCOC1,,[Li+].[OH-],,test
US20160152624A1,CCOC(=O)Cc1ccc(N2CCc3c(C)nc(Cl)nc32)cc1.COc1ccc(B(O)O)cc1Cl>>CCOC(=O)Cc1ccc(N2CCc3c(C)nc(-c4ccc(OC)c(Cl)c4)nc32)cc1,,C1COCCO1,,ClCCl,O=C([O-])[O-].[Cs+].[Cs+],test
US20080214654A1,COc1cc(CN(CCCNC(=O)OC(C)(C)C)C(=O)c2ccc(Cl)cc2)ccc1OCc1ccc(F)cc1.Cl>>COc1cc(CN(CCCN)C(=O)c2ccc(Cl)cc2)ccc1OCc1ccc(F)cc1.Cl,,C1COCCO1,,,,test
US20100298340A1,CN(Cc1ccc(C(=O)O)cc1)c1ccccc1.Cc1nc(N=C(N)N)sc1-c1ccc(N)cc1>>Cc1nc(NC(=N)N)sc1-c1ccc(NC(=O)c2ccc(CN(C)c3ccccc3)cc2)cc1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US04820827,BrBr.CSc1ccc(-c2ccsc2-c2ccc(F)cc2)cc1>>CSc1ccc(-c2cc(Br)sc2-c2ccc(F)cc2)cc1,,CC(=O)O,ClCCl,,,test
US20110178130A1,C=CCBr.CC(C)(C)OC(=O)N[C@@H](CC1CCC(O)CC1)C(=O)O>>C=CCOC1CCC(C[C@H](NC(=O)OC(C)(C)C)C(=O)O)CC1,,CN(C)C=O,,[H-].[Na+],,test
US20060258838A1,COC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OCc1ccccc1>>COC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@H](N)Cc1c[nH]c2ccccc12,,CO,,,,test
US20130225554A1,CC(C)(C)OC(=O)N1CCC[C@H]1CONC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1>>CC(C)(C)OC(=O)N1CCC[C@H]1CONC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2O,[Pd],CO,,,,test
US20110021511A1,NC(=O)c1[nH]c2cc(Br)ccc2c1N.O=C(Cl)OC(Cl)(Cl)Cl>>O=c1[nH]c(=O)c2[nH]c3cc(Br)ccc3c2[nH]1,,C1COCCO1,,O,,test
US20090215628A1,CC(=O)Cl.CNC(=O)C(NC(=O)c1ccc(F)cc1C(F)(F)F)C(CN)c1ccccc1>>CNC(=O)C(NC(=O)c1ccc(F)cc1C(F)(F)F)C(CNC(C)=O)c1ccccc1,,ClCCl,,CCN(CC)CC,,test
US04775756,COc1cccc(OC)c1N.O=C1NC(=O)C(=O)C(=O)N1>>COc1cc(C2(O)C(=O)NC(=O)NC2=O)cc(OC)c1N,,O,,,,test
US20040259874A1,CCC(=O)Cl.COC(=O)[C@H](C)N>>CCC(=O)N[C@@H](C)C(=O)OC,,ClCCl,,CCN(CC)CC,Cl,test
US20090215785A1,CC1(C(=O)c2c[nH]c3ncc(Br)nc23)CCC(OCc2ccccc2)CC1>>CC1(C(=O)c2c[nH]c3nccnc23)CCC(OCc2ccccc2)CC1,[Pd],CCO,,[K+].[OH-],,test
US20090054411A1,CN1CCNCC1.COCCOc1cc([N+](=O)[O-])ccc1Cl>>COCCOc1cc([N+](=O)[O-])ccc1N1CCN(C)CC1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20160206616A1,CCOC(=O)C1=C(CBr)NC(c2nccs2)=NC1c1ccc(Cl)cc1Cl.O=C(O)[C@@H]1CS(=O)(=O)CCN1>>CCOC(=O)C1=C(CN2CCS(=O)(=O)C[C@H]2C(=O)O)NC(c2nccs2)=NC1c1ccc(Cl)cc1Cl,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20090131468A1,NS(=O)(=O)c1ccccc1S(N)(=O)=O.O=C(O)c1ccc(-c2nc3ccccc3o2)cc1>>NS(=O)(=O)c1ccccc1S(=O)(=O)NC(=O)c1ccc(-c2nc3ccccc3o2)cc1,CN(C)c1ccncc1,CN(C)C=O,,ClCCCl,,test
US20020032208A1,COc1cc2c(=O)[nH]cnc2cc1OCc1ccccc1.O=S(Cl)Cl>>COc1cc2c(Cl)ncnc2cc1OCc1ccccc1.Cl,,CN(C)C=O,,,,test
US06207778B1,C=C(C)C(=O)NCCCN(C)C.CCCCCCCCCCC=CCl>>C=C(C)C(=O)NCCC[N+](C)(C)CCCCCCCCCCCC.[Cl-],O=S(=O)(O)O,O,,,,test
US20010051620A1,COc1cc(Nc2c(C#N)cnc3cc(N=[N+]=[N-])c([N+](=O)[O-])cc23)cc(OC)c1OC>>COc1cc(Nc2c(C#N)cnc3cc(N)c(N)cc23)cc(OC)c1OC,[Pd],C1CCOC1,CCO,,,test
US20040010007A1,Cc1nc(Oc2ccccc2)c([N+](=O)[O-])c(NCCCO)c1C.O=S(Cl)Cl>>Cc1nc(Oc2ccccc2)c([N+](=O)[O-])c(NCCCCl)c1C.Cl,,ClCCl,,,,test
US05629433,CC(=O)O[C@H]1C(=O)[C@]2(C)[C@@H](O)C[C@H]3OC[C@@]3(OC(C)=O)[C@H]2[C@H](OC(=O)c2ccccc2)[C@]2(O)C[C@H](O)C(C)=C1C2(C)C>>CC(=O)O[C@@]12CO[C@@H]1C[C@@H](O)[C@@]1(C)C(=O)[C@H](O)C3=C(C)[C@@H](O)C[C@@](O)([C@@H](OC(=O)c4ccccc4)[C@H]21)C3(C)C,,O,,,,test
US20090069337A1,Cl.Nc1ccc2c(c1)NC(=O)CC2.O=S=O>>O=C1CCc2ccc(S(=O)(=O)Cl)cc2N1,Cl[Cu],CC(=O)O,O,O=N[O-].[Na+],,test
US20040138462A1,CCOC(=O)COc1ccc(S(=O)(=O)c2ccc(CCNC[C@H](O)c3cccc(Cl)c3)cc2)cc1.Cl>>CCOC(=O)COc1ccc(S(=O)(=O)c2ccc(CCNC[C@H](O)c3cccc(Cl)c3)cc2)cc1.Cl,,CCO,,,,test
US05763599,C=O.O=[N+]([O-])c1ccccc1CCl>>O=[N+]([O-])c1ccccc1C(Cl)CO,CC(=O)O,CS(C)=O,ClCCl,C1CCC2=NCCCN2CC1,,test
US20030032623A1,O=C(n1ccnc1)n1ccnc1.c1cc(CCCNCCCNCCC23CC4CC(CC(C4)C2)C3)ccn1>>O=C1N(CCCc2ccncc2)CCCN1CCC12CC3CC(CC(C3)C1)C2,,ClCCl,,,,test
US20120283297A1,CC(C)Oc1ccc(-c2nc(-c3cccc4[nH]ncc34)no2)cc1Cl.COC(=O)CCCCBr>>COC(=O)CCCCn1ncc2c(-c3noc(-c4ccc(OC(C)C)c(Cl)c4)n3)cccc21,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20140155419A1,Cc1ccc(C(N)c2ccccc2)c(C)c1.Cc1ncccc1C(=O)COc1ccc(CC(=O)O)cc1>>Cc1ccc(C(NC(=O)Cc2ccc(OCC(=O)c3cccnc3C)cc2)c2ccccc2)c(C)c1,,ClCCl,,ClCCCl,On1nnc2ccccc21,test
US20030144507A1,Nc1ccc2c(C(F)(F)F)cc(=O)oc2c1.O=S(=O)(Cl)c1ccc(Cl)cc1>>O=c1cc(C(F)(F)F)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2o1,CN(C)c1ccncc1,c1ccncc1,,Cl,,test
US20130310394A1,Nc1ccc(C2CN=C3c4ccccc4NC(=O)N3C2)cc1.O=C=Nc1ccc(Cl)c(C(F)(F)F)c1>>O=C(Nc1ccc(C2CN=C3c4ccccc4NC(=O)N3C2)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1,,C1CCOC1,,,,test
US20110269740A1,CCOC(=O)C(=O)Cl.NC(=O)c1cc(Cl)cn1N>>CCOC(=O)C(=O)Nn1cc(Cl)cc1C(N)=O,,C1CCOC1,,c1ccncc1,,test
US06013658,CC(C)(C)OC(=O)N1CCC(C(=O)O)CC1.N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@H](Cc1ccc2ccccc2c1)c1nnnn1CCc1ccccc1>>CC(C)(C)OC(=O)N1CCC(C(=O)N[C@H](Cc2ccc3ccccc3c2)C(=O)N[C@H](Cc2ccc3ccccc3c2)c2nnnn2CCc2ccccc2)CC1,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20070249670A1,Cc1cc(C)c(N=C=O)c(C)c1.Nc1cc(-c2ccc(F)c(F)c2)ccc1C(=O)N[C@@H](CCC(=O)OCc1ccccc1)C(=O)OCc1ccccc1>>Cc1cc(C)c(NC(=O)Nc2cc(-c3ccc(F)c(F)c3)ccc2C(=O)N[C@@H](CCC(=O)OCc2ccccc2)C(=O)OCc2ccccc2)c(C)c1,,c1ccncc1,,,,test
US20070105943A1,COC1CC(C=O)C(OC)O1.NCc1ccccc1>>O=Cc1ccn(Cc2ccccc2)c1,,CCOC(C)=O,,CC(=O)O,O,test
US20140228343A1,CI.COC(=O)c1ccc2nc[nH]c2c1.COC(=O)c1ccc2ncn(C)c2c1>>COC(=O)c1ccc2c(c1)ncn2C,,C1CCOC1,,[H-].[Na+],,test
US20090054435A1,COCOc1cc(OC)ccc1C(=O)c1ccc(O)cc1C.Cc1oc(-c2ccccc2)nc1CCl>>COCOc1cc(OC)ccc1C(=O)c1ccc(OCc2nc(-c3ccccc3)oc2C)cc1C,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20160075698A1,O=C(/C=C/c1cnc2ccc(F)cc2c1)CCCCc1ccc2c(n1)NCCC2>>OC(/C=C/c1cnc2ccc(F)cc2c1)CCCCc1ccc2c(n1)NCCC2,,CO,,Cl,[BH4-].[Na+],test
US20100190782A1,COC(=O)c1nc(Br)ccc1O.COc1ccc(CBr)cc1>>COC(=O)c1nc(Br)ccc1OCc1ccc(OC)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20070244095A1,COC(=O)c1ccc(CN2CCC[C@H](N(Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)c3nnn(C)n3)c3cc(C)c(C(F)(F)F)cc32)cc1>>Cc1cc2c(cc1C(F)(F)F)N(Cc1ccc(C(=O)O)cc1)CCC[C@@H]2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1,,CO,,Cl,[Na+].[OH-],test
US20160244437A1,Cc1cc(C(=O)N[C@@H]2CCCNC2=O)ccc1-c1cccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc3nc(C(F)(F)C(F)(F)F)[nH]c3c2)c1.Cl>>Cc1cc(C(=O)N[C@@H]2CCCNC2=O)ccc1-c1cccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CN)CC2)C(=O)Nc2ccc3nc(C(F)(F)C(F)(F)F)[nH]c3c2)c1.Cl,,C1COCCO1,ClCCl,CC#N,,test
US20090215882A1,C1COCCO1.CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@@]1(C)C(=O)[C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c4ccccc4)C[C@@](O)([C@@H](OC(=O)c4ccccc4)[C@H]21)C3(C)C>>C[C@@H]1CC[C@H]2C[C@@H]3[C@H](C)CCC[C@@]3(C)CC[C@@H]1C2(C)C,,C1COCCO1,,,,test
US04537622,CC(C)COC(=O)Nc1cccc(OC(=O)Cl)c1.CNc1ccc(Cl)cc1>>CC(C)COC(=O)Nc1cccc(OC(=O)N(C)c2ccc(Cl)cc2)c1,,CCOC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20080021028A1,CC(C)OC(=O)[C@H](O)[C@H](Cc1ccccc1)C(=O)OC(C)C>>O=C(O)[C@H](Cc1ccccc1)[C@H](O)C(=O)O,,C1CCOC1,O,[K+].[OH-],,test
US05556864,CN(C)CCCCl.Oc1ccccc1CCCCc1ccccc1>>CN(C)CCCOc1ccccc1CCCCc1ccccc1,,CC(=O)N(C)C,,Cl,[H-].[Na+],test
US05459273,CN(C)C=CC#N.CN(C)C=O.CN(C)C=O.Cl>>N#Cc1ccc(Cl)nc1,,Cl,,O,,test
US20140213586A1,COc1cc(N)cc(CO)c1.O=Cc1ccc(F)cc1>>COc1cc(CO)cc(N=Cc2ccc(F)cc2)c1,,CCO,,,,test
US20110263662A1,CNC(CNC(=O)OC(C)(C)C)C1CC1.Cc1nc(C(=O)O)c(-c2ccccc2)s1>>Cc1nc(C(=O)N(C)C(CNC(=O)OC(C)(C)C)C2CC2)c(-c2ccccc2)s1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100130474A1,CC(CC(=O)O)CN1CCCC1.CN(C)C=O.Cc1ccc(-c2n[nH]c(N)c2F)cn1>>Cc1ccc(-c2[nH]nc(NC(=O)CC(C)CN3CCCC3)c2F)cn1.O=CO,,CN(C)C=O,,Cl,O=C(n1ccnc1)n1ccnc1,test
US20080182993A1,CC(C)(C)c1cc(C(=O)CBr)cc(C(C)(C)C)c1O.CN(CC(=O)O)C(=O)OCc1ccccc1>>CN(CC(=O)OCC(=O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)C(=O)OCc1ccccc1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US04294835,CC(=O)Oc1ccccc1C(=O)NC(Cl)C(Cl)(Cl)Cl.CCS>>CCSC(NC(=O)c1ccccc1OC(C)=O)C(Cl)(Cl)Cl,,O,,CCN(CC)CC,ClCCl,test
US20070093526A1,CC(C)CN(Cc1cscn1)C1CCN(C(=O)OC(C)(C)C)CC1>>CC(C)CN(Cc1cscn1)C1CCNCC1,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US20120129840A1,CCCC(C(=O)OC)c1c(C)nc(N2CCCCC2)nc1-c1ccc(OC)cc1F>>CCCC(C(=O)O)c1c(C)nc(N2CCCCC2)nc1-c1ccc(OC)cc1F,,CO,,[Na+].[OH-],,test
US05646184,CC(C)=CCC/C(C)=C/CBr.Nc1ccc(C(=O)O)c(O)c1>>CC(C)=CCC/C(C)=C/CNc1ccc(C(=O)O)c(O)c1,,CN(C)C=O,,O,,test
US20100273793A1,COC(=O)/N=C(/NC(=O)OC)SC.Nc1ccc(OCc2c(Cl)cccc2Cl)cc1N>>COC(=O)Nc1nc2ccc(OCc3c(Cl)cccc3Cl)cc2[nH]1,,CC(=O)O,CO,,,test
US20090298807A1,CC(=O)c1ccc(OCc2ccccc2)c(N)c1O.O=C(Cl)CCl>>CC(=O)c1ccc(OCc2ccccc2)c2c1OCC(=O)N2,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],O=C([O-])O.[Na+],test
US20010027196A1,CSc1nc(N)nc(Cl)c1C#N.O=S(=O)(c1ccccc1)N1OC1c1ccccc1>>CS(=O)c1nc(N)nc(Cl)c1C#N,,CN(C)C=O,ClCCl,,,test
US04290947,CC(C)(C)[Si](C)(C)Cl.O=C1C[C@@H](CI)N1>>CC(C)(C)[Si](C)(C)N1C(=O)C[C@H]1CI,,CN(C)C=O,,CCN(CC)CC,,test
US20060258666A1,CC(C)(C)NS(=O)(=O)c1ccc(N)cc1.O=C1CCC(=O)N1Br>>CC(C)(C)NS(=O)(=O)c1ccc(N)c(Br)c1,,ClCCl,,,,test
US20070105838A1,CC(C)(C)OC(=O)N1Cc2ccc(C(N)=O)cc2C1>>CC(C)(C)OC(=O)N1Cc2ccc(C#N)cc2C1,,c1ccncc1,,Cc1ccc(S(=O)(=O)Cl)cc1,,test
US20010044539A1,C=CCC1CCCCc2noc(=O)n21.CCOC(=O)/C(Cl)=N\O>>CCOC(=O)C1=NOC(CC2CCCCc3noc(=O)n32)C1,,Cc1ccccc1,,,,test
US04634710,COc1cc(CO)ncc1C.O=S(Cl)Cl>>COc1cc(CCl)ncc1C.Cl,,ClCCl,,CCOCC,,test
US05286888,O=CCC(=O)c1ccccc1>>OCC[C@H](O)c1ccccc1,,CO,,CC(C)OC(C)C,,test
US20110190342A1,N[C@@H](Cc1ccc(Oc2nccc3ccc(Br)cc23)cc1)C(=O)O.O=C(O)c1cc2cc(Cl)ccc2nc1Cl>>O=C(O)c1cc2cc(Cl)ccc2nc1N[C@@H](Cc1ccc(Oc2nccc3ccc(Br)cc23)cc1)C(=O)O,,CS(C)=O,,,,test
US04818756,N.O=S(=O)(Cl)c1ccccc1S(=O)(=O)Cl>>O=S1(=O)NS(=O)(=O)c2ccccc21,,CCO,Cc1ccccc1,,,test
US20100105906A1,COC(=O)c1ccc(C#C[Si](C)(C)C)cc1Cl>>C#Cc1ccc(C(=O)OC)c(Cl)c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100184761A1,CC(=O)Cl.CC(C)NCCCOc1ccc(-c2cc3[nH]cnc3c(C#N)n2)cc1C(F)(F)F.CCN(C(C)C)C(C)C>>CC(=O)N(CCCOc1ccc(-c2cc3c(ncn3C)c(C#N)n2)cc1C(F)(F)F)C(C)C,,C1CCOC1,,,,test
US20070232627A1,CC(C)(C)c1ccc(Sc2ccc(NC(=O)c3cccc(C(F)(F)F)c3)cc2[N+](=O)[O-])cc1.Cc1ccc(S)cc1>>Cc1ccc(Sc2ccc(NC(=O)c3cccc(C(F)(F)F)c3)cc2[N+](=O)[O-])cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US20130172292A1,Br[Mg]c1ccc(OCc2ccccc2)cc1.CON(C)C(=O)c1nccnc1Cl>>O=C(c1ccc(OCc2ccccc2)cc1)c1nccnc1Cl,,C1CCOC1,,,,test
US20060166990A1,Cc1ccc(I)cc1C(=O)c1ccc(Nc2ccc(F)cc2F)cc1Cl.OCc1cccc(B(O)O)c1>>Cc1ccc(-c2cccc(CO)c2)cc1C(=O)c1ccc(Nc2ccc(F)cc2F)cc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CCOC(C)=O,COCCOC,O,O=C([O-])O.[Na+],test
US20120329791A1,CC(C)(C)OC(=O)NC1(c2ccc(-n3c(-c4cccnc4N)nc4ccc(-c5cccc(N6CCO[C@@H](CO)C6)c5)nc43)cc2)CCC1.Cl.ClCCl>>Cl.Cl.Cl.Nc1ncccc1-c1nc2ccc(-c3cccc(N4CCO[C@@H](CO)C4)c3)nc2n1-c1ccc(C2(N)CCC2)cc1,,ClCCl,,C1COCCO1,,test
US20150175575A1,COC(=O)c1cn(-c2cc(N3CCOCC3)cc([N+](=O)[O-])c2)cn1>>COC(=O)c1cn(-c2cc(N)cc(N3CCOCC3)c2)cn1,,CCOC(C)=O,CN(C)C=O,,,test
US20130190287A1,CC(C)Nc1nc(Nc2ccnc(C(F)(F)F)c2)nc(-c2cccc(C3(O[Si](C)(C)C(C)(C)C)CC3)c2)n1>>CC(C)Nc1nc(Nc2ccnc(C(F)(F)F)c2)nc(-c2cccc(C3(O)CC3)c2)n1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100222325A1,Cn1cc(Br)cc(N)c1=O.NCCO.S=C(Cl)Cl>>Cn1cc(Br)cc(NC(=S)NCCO)c1=O,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20090215800A1,COc1cc2c(Oc3ccc(NC(=O)c4ccccc4)cc3)ccnc2cc1OCC[C@H](N)C(=O)OC1CCCC1.O=C1CCCCC1>>COc1cc2c(Oc3ccc(NC(=O)c4ccccc4)cc3)ccnc2cc1OCC[C@H](NC1CCCCC1)C(=O)OC1CCCC1,CC(=O)O,CO,,[BH3-]C#N.[Na+],,test
US20090203697A1,COC(=O)[C@H]1CCCC(=O)N1C(=O)OC(C)(C)C.Fc1ccc([Mg]Br)cc1>>COC(=O)[C@@H](CCCC(=O)c1ccc(F)cc1)NC(=O)OC(C)(C)C,,C1CCOC1,,CCOC(C)=O,[Cl-].[NH4+],test
US20110136782A1,CC1(C)CNC(=O)c2cc(Cl)ccc2O1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CC1(C)CNC(OS(=O)(=O)C(F)(F)F)c2cc(Cl)ccc2O1,,ClCCl,,Cc1cccc(C)n1,,test
US20060264460A1,N#Cc1cnc2ccc(N)cc2c1Nc1ccc(F)c(Cl)c1.O=Cc1cnc(N2CCOCC2)s1>>N#Cc1cnc2ccc(NCc3cnc(N4CCOCC4)s3)cc2c1Nc1ccc(F)c(Cl)c1,,CCO,,[BH3-]C#N.[Na+],,test
US20030078251A1,CC(=O)Cl.COc1cccc([C@H]2O[C@H](CC(=O)N[C@H](C)C(=O)O)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC>>COc1cccc([C@H]2O[C@H](CC(=O)N[C@H](C)C(=O)O)C(=O)N(CC(C)(C)COC(C)=O)c3ccc(Cl)cc32)c1OC,,O,,CCOC(C)=O,c1ccncc1,test
US05773423,NCc1cccc(I)c1.OC[C@H]1O[C@@H](n2cnc3c(Cl)ncnc32)[C@H](O)[C@@H]1O>>OC[C@H]1O[C@@H](n2cnc3c(NCc4cccc(I)c4)ncnc32)[C@H](O)[C@@H]1O,,CCO,,CCN(CC)CC,Cl,test
US04937373,COc1c(C)ccc(C)c1OC.O=C(Cl)CCCCCBr>>COc1c(C)cc(C(=O)CCCCCBr)c(C)c1OC,,ClCCl,,O,[Al+3].[Cl-].[Cl-].[Cl-],test
US20050075392A1,CC(C)(C)OC(=O)N[C@H](COCc1ccccc1)CC(=O)O.CCI>>CCOC(=O)C[C@@H](COCc1ccccc1)NC(=O)OC(C)(C)C,,CO,O,O=C([O-])[O-].[Cs+].[Cs+],,test
US04806145,COC(=O)C(C)Oc1cc(-n2nc(C)n(C(F)F)c2=O)c(Cl)cc1C>>Cc1cc(Cl)c(-n2nc(C)n(C(F)F)c2=O)cc1OC(C)C(=O)O,,CCO,O,[K+].[OH-],,test
US20060063814A1,CCOC(=O)[C@H](Cc1ccc(O)c([N+](=O)[O-])c1)NC(=O)OC(C)(C)C>>CCOC(=O)C(Cc1ccc(O)c(N)c1)NC(=O)OC(C)(C)C,[Zn],CO,O,[Cl-].[NH4+],,test
US20090186200A1,COc1ccc(Nc2cc(C(=O)O)c(Nc3ccc(OC)cc3)cc2C(=O)O)cc1>>O=c1c2ccccc2[nH]c2cc3c(=O)c4ccccc4[nH]c3cc12,,CO,O,,,test
US04397677,CC1(CBr)OCCO1.CCN>>CCNCC1(C)OCCO1,,CCOCC,,[Na+].[OH-],,test
US20050004167A1,NNC(=O)c1ccc2c(c1)CCO2.O=S(=O)(Cl)c1ccccc1>>O=C(NNS(=O)(=O)c1ccccc1)c1ccc2c(c1)CCO2,CN(C)c1ccncc1,C1CCOC1,CCOC(C)=O,CCN(C(C)C)C(C)C,,test
US20090054402A1,CCOC(=O)c1cc2c(Cl)ccc(Br)c2[nH]1.Cc1ccccc1B(O)O>>CCOC(=O)c1cc2c(Cl)ccc(-c3ccccc3C)c2[nH]1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,[Cs+].[F-],,test
US20140171309A1,CC(C)NNC(=O)OC(C)(C)C.NCC(F)(F)F.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>CC(C)N(NC(=O)OC(C)(C)C)C(=O)NCC(F)(F)F,,ClCCl,,O,,test
US05034451,C=CCOC(C)=O.C=COC(C)=O>>C=CCOC(C)=O.C=COC(C)=O,,CO,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20100286125A1,CC(C)(C)[Si](OCCCC=O)(c1ccccc1)c1ccccc1.Clc1ccc(Br)cc1>>CC(C)(C)[Si](OCCCC(O)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1,,C1CCOC1,,II,,test
US20080269196A1,CC(C)(C)S.N#Cc1ccc(CBr)nc1>>CC(C)(C)SCc1ccc(C#N)cn1,,CN(C)C=O,ClCCl,O,O=C([O-])[O-].[Cs+].[Cs+],test
US05824802,CI.CS(=O)(=O)c1ccc(C(=O)O)c(Cl)c1N1CCC(O)CC1>>COC1CCN(c2c(S(C)(=O)=O)ccc(C(=O)O)c2Cl)CC1,,C1CCOC1,O,Cl,[H-].[Na+],test
US05039691,C=CCBr.O=C(O)C(c1ccccc1)c1ccccc1>>C=CCC(C(=O)O)(c1ccccc1)c1ccccc1,,C1CCOC1,CCCCCC,CCOCC,Cl,test
US05677464,C[C@@H](n1ncn(-c2ccc(OCC(F)(F)C(F)F)cc2)c1=O)[C@](O)(COS(C)(=O)=O)c1ccc(F)cc1F.c1nc[nH]n1>>C[C@@H](n1ncn(-c2ccc(OCC(F)(F)C(F)F)cc2)c1=O)[C@](O)(Cn1cncn1)c1ccc(F)cc1F,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160115179A1,C1COCCOCCOCCOCCOCCO1.C=CCN1C(=O)C(=O)c2ccccc21.C[Si](C)(C)c1ccccc1OS(=O)(=O)C(F)(F)F.c1ccncc1>>C=CCN1C(=O)C(Oc2ccccc2)(c2ccccn2)c2ccccc21,,C1CCOC1,,[F-].[K+],,test
US20060025423A1,CC(C)COC(=O)Cl.O=S(=O)(Nc1ncc(Br)nc1OCc1cccnc1)c1cccc(Cl)c1Cl>>CC(C)COC(=O)N(c1ncc(Br)nc1OCc1cccnc1)S(=O)(=O)c1cccc(Cl)c1Cl,,COCCOC,,[H-].[Na+],,test
US07189851B2,CCOC(=O)c1c(CCc2ccc(F)cc2)cc2c(c1-c1ccc(C(=O)OCc3ccccc3)cc1)C(=O)N1CCC[C@@H]21>>CCOC(=O)c1c(CCc2ccc(F)cc2)cc2c(c1-c1ccc(C(=O)O)cc1)C(=O)N1CCC[C@@H]21,[Pd],CCOC(C)=O,,,,test
US20140128372A1,CON(C)C(=O)[C@H](C)NC(=O)OCc1ccccc1.C[Mg]Br>>CC(=O)[C@H](C)NC(=O)OCc1ccccc1,,C1CCOC1,,Cc1ccccc1,O,test
US07250410B2,CI.COc1cc2c(cc1OC)C(c1ccc(Br)cc1)=NCC(=O)N2>>CCOc1cc2c(cc1OC)NC(=O)CN=C2c1ccccc1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US04076941,CC(C)N=C=O.O=C(O)CNC(=O)Nc1cc(Cl)cc(Cl)c1>>CC(C)NC(=O)N1CC(=O)N(c2cc(Cl)cc(Cl)c2)C1=O,,Clc1ccccc1,,CCN(CC)CC,Cl,test
US20100216802A1,CC(C)(C)[Si](C)(C)Cl.N[C@@H](CCO)C(=O)O>>CC(C)(C)[Si](C)(C)OC(=O)[C@@H](N)CCO,,CC#N,,C1CCC2=NCCCN2CC1,,test
US07094798B1,COC(=O)C(=Cc1ccc(OCc2ccccc2)c(OC)c1)N=[N+]=[N-]>>COC(=O)c1cc2cc(OC)c(OCc3ccccc3)cc2[nH]1,,Cc1ccccc1C,,,,test
US05466698,C#CCCOS(=O)(=O)c1ccc(C)cc1.C1=C(c2ccccc2)CCNC1>>C#CCCN1CC=C(c2ccccc2)CC1,,CN(C)C=O,,O=C([O-])O.[Na+],,test
US20100069436A1,COCCn1c(SC)nc(-c2ccc(F)cc2)c1-c1ccnc(NC(=O)C2CCOCC2)c1.O>>COCCn1c(S(C)=O)nc(-c2ccc(F)cc2)c1-c1ccnc(NC(=O)C2CCOCC2)c1,,C1CCOC1,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20030236260A1,CCc1nc2c(C)cc(C)nc2n1-c1ccc(CCO)cc1.Cc1ccc(S(=O)(=O)N=C=O)cc1>>CCc1nc2c(C)cc(C)nc2n1-c1ccc(CCOC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1,,ClCCl,,,,test
US20140213616A1,COc1ccc(O)cc1F.O=C(Nc1cc[nH]c(=O)c1)c1ccc(C(F)(F)F)cc1F>>COc1ccc(Oc2cc(C(F)(F)F)ccc2C(=O)Nc2cc[nH]c(=O)c2)cc1F,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090069297A1,CCOC(=O)C(=CNc1cncc(Br)c1)C(=O)OCC>>CCOC(=O)c1c[nH]c2cc(Br)cnc2c1=O,,CC#N,,c1ccc(Oc2ccccc2)cc1,,test
US20090163488A1,Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4c3)c2)n(C)n1.Cc1ccc(S(=O)(=O)O)cc1>>Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4c3)c2)n(C)n1.Cc1ccc(S(=O)(=O)O)cc1,,CCO,CCOC(C)=O,O,,test
US20160052884A1,COc1cn(CC(=O)OC(C)(C)C)c(=O)cc1-c1cc(Cl)ccc1C#N.O=S(=O)(OCC1CCCCO1)C(F)(F)F>>COc1cn(C(CC2CCCCO2)C(=O)OC(C)(C)C)c(=O)cc1-c1cc(Cl)ccc1C#N,,C1CCOC1,,,,test
US20040044041A1,BrCc1ccc(I)cc1.Nc1ncccc1[N+](=O)[O-]>>O=[N+]([O-])c1cccnc1NCc1ccc(I)cc1,,CN(C)C=O,,[H-].[Na+],,test
US04786640,CC(C)(C)OC(=O)CBr.N#Cc1c(Cc2cccc3ccccc23)nc(-c2cccc3c(Br)cccc23)[nH]c1=O>>CC(C)(C)OC(=O)COc1nc(-c2cccc3c(Br)cccc23)nc(Cc2cccc3ccccc23)c1C#N,,CN(C)C=O,,[H-].[Na+],,test
US05837708,COc1cccc(Cc2nc(Cl)c(Oc3ccccc3OC)c(NS(=O)(=O)c3ccc(C(C)C)cn3)n2)c1.OCCO>>COc1cccc(Cc2nc(NS(=O)(=O)c3ccc(C(C)C)cn3)c(Oc3ccccc3OC)c(OCCO)n2)c1,,OCCO,,,,test
US20100190980A1,COC(=O)c1nc(Br)cnc1Br.Fc1ccc(S)cc1>>COC(=O)c1nc(Br)cnc1Sc1ccc(F)cc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20060167246A1,COC(=O)c1cc2[nH]c(-c3ccccc3N)c(C3CCCCC3)c2s1.O=C(Cl)CCl>>COC(=O)c1cc2[nH]c(-c3ccccc3NC(=O)CCl)c(C3CCCCC3)c2s1,,C1CCOC1,,CC(=O)O,CC(=O)[O-].[Na+],test
US04816454,CC1CC(=O)NN=C1c1ccc(N)cc1.O=C(Cl)COc1ccc(Cl)cc1>>CC1CC(=O)NN=C1c1ccc(NC(=O)COc2ccc(Cl)cc2)cc1,CN(C)c1ccncc1,c1ccncc1,,,,test
US20090023763A1,CN(C)/C=C(/C(=O)c1cccc(F)c1)c1ccncn1.N#CCC(N)=O>>N#Cc1cc(-c2ccncn2)c(-c2cccc(F)c2)[nH]c1=O,,CN(C)C=O,,C[O-].[Na+],,test
US20080021023A1,CNC(CN1CCOCC1)c1ccc(-c2ccccc2)cc1.Cc1cc2ccc(=O)n(CC(=O)O)c2cc1C>>Cc1ccc2c(ccc(=O)n2CC(=O)N(C)C(CN2CCOCC2)c2ccc(-c3ccccc3)cc2)c1C,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05506227,CCC=Cc1cccc(C)n1>>CCCCc1cccc(C)n1,[Pd],CCOC(C)=O,,[H][H],,test
US04329347,Cc1cc(=O)[nH]c2ccc(OCCCCSc3ccccn3)cc12.O>>Cc1cc(=O)[nH]c2ccc(OCCCCS(=O)c3ccccn3)cc12,,CC(=O)O,O,[Na+].[O-][I+3]([O-])([O-])[O-],,test
US20110166116A1,CS(=O)(=O)c1ccc(N2CCC(=NOC3CCN(c4ccccn4)CC3)CC2)c(F)c1.O=C(Oc1ccc([N+](=O)[O-])cc1)OC1CCC1>>CS(=O)(=O)c1ccc(N2CCC(=NOC3CCN(C(=O)OC4CCC4)CC3)CC2)c(F)c1,,ClCCl,,,,test
US20060128790A1,Cc1c(O)cc2c(c1C)OCC1(CC1)C2=O>>Cc1c(O)cc2c(c1C)OCC1(CC1)C2O,,CO,,[BH4-].[Na+],,test
US20050037925A1,Cc1cccc(C2CC2)c1Oc1nnc(Cl)cc1O.O=C1CCC(=O)N1Br>>Cc1cccc(C2CC2)c1Oc1nnc(Cl)c(Br)c1O,,O,,CN(C)C=O,Cl,test
US05478728,C1=CCC=C1.O=C(/C(=C\c1ccccc1)[N+](=O)[O-])c1ccccc1>>O=C(c1ccccc1)[C@@]1([N+](=O)[O-])[C@@H]2C=C[C@@H](C2)[C@H]1c1ccccc1,,ClCCl,,,,test
US20040034071A1,Cc1cccc(Sc2ccc(S(=O)(=O)N[C@@H](C(=O)OC(C)(C)C)C(C)C)cc2)c1.ClCCN1CCOCC1>>Cc1cccc(Sc2ccc(S(=O)(=O)N(CCN3CCOCC3)[C@@H](C(=O)OC(C)(C)C)C(C)C)cc2)c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US04298602,CCOP(=S)(Cl)OCC.Cc1nc(O)nn1-c1cccc(F)n1>>CCOP(=S)(OCC)Oc1nc(C)n(-c2cccc(F)n2)n1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20150148340A1,CCOC(=O)c1cn(-c2ccc3[nH]c(=O)n(C)c3c2)c(=O)[nH]c1=O.Cc1c(CBr)cccc1C(F)(F)F>>CCOC(=O)c1cn(-c2ccc3[nH]c(=O)n(C)c3c2)c(=O)n(Cc2cccc(C(F)(F)F)c2C)c1=O,,CN(C)C=O,O,[I-].[K+],,test
US20150344489A1,CCOc1ncccc1C1(N)C(=O)N(S(=O)(=O)c2ccc(OC)cc2OC)c2ccc(C#N)cc21.O=C(Cl)Oc1ccccc1>>CCOc1ncccc1C1(NC(=O)Oc2ccccc2)C(=O)N(S(=O)(=O)c2ccc(OC)cc2OC)c2ccc(C#N)cc21,,ClCCl,,c1ccncc1,,test
US05877199,CCOCC.C[Mg]I.N#Cc1cccc2c1ccn2Cc1ccccc1>>CC(=O)c1cccc2c1ccn2Cc1ccccc1,,C1CCOC1,,[Cl-].[NH4+],,test
US20070149506A1,CCNCC.O=C(Cl)c1cccnc1Cl>>CCN(CC)C(=O)c1cccnc1Cl,,ClCCl,,,,test
US05177095,CCCCc1nnc(SCc2ccc([N+](=O)[O-])cc2)n1Cc1ccc(OC(C(=O)OC)c2ccccc2)cc1.O=C(OO)c1cccc(Cl)c1>>CCCCc1nnc(S(=O)Cc2ccc([N+](=O)[O-])cc2)n1Cc1ccc(OC(C(=O)O)c2ccccc2)cc1,,ClCCl,,,,test
US06380387B1,CC(=O)OC(C)Cl.Cc1c(-c2ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)O)cc2)c(=O)n(C)c(=O)n1C>>CC(=O)OC(C)OC(=O)[C@H](Cc1ccc(-c2c(C)n(C)c(=O)n(C)c2=O)cc1)NC(=O)OC(C)(C)C,,CN(C)C=O,,O,O=C([O-])O.[Na+],test
US20150225342A1,CC(C)[Si](Cl)(C(C)C)C(C)C.Oc1cnc(Cl)nc1>>CC(C)[Si](Oc1cnc(Cl)nc1)(C(C)C)C(C)C,,C1CCOC1,O,CCN(CC)CC,,test
US20150112073A1,O=C(O)CCSCC1CC1(F)F.O=S(Cl)Cl>>O=C(Cl)CCSCC1CC1(F)F,,ClCCl,,,,test
US20080132539A1,CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1.CC(C)=O.CCI>>CCCn1cc(C[C@H](NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2)c2ccccc21,,CC(C)=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20090275581A1,CC(C)(C)OC(=O)N[C@@H]1CN(Cc2ccccc2)C[C@@H]1O[Si](C)(C)C(C)(C)C>>CC(C)(C)OC(=O)N[C@@H]1CN(Cc2ccccc2)C[C@@H]1O,,CC#N,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20120142717A1,COC(=O)/C=C/c1cnc(OC)nc1>>COC(=O)CCc1cnc(OC)nc1,[Pd],CO,,,,test
US20130310384A1,CC[C@@H](c1ccccc1)N(Cc1ccc(C(=O)O)cc1)S(=O)(=O)c1ccc(Cl)cc1.OC[C@@H]1CCCN1>>CC[C@@H](c1ccccc1)N(Cc1ccc(C(=O)N2CCC[C@@H]2CO)cc1)S(=O)(=O)c1ccc(Cl)cc1,,ClCCl,,CCN(CC)CC,CS(=O)(=O)Cl,test
US20140212486A1,CC(C)=CCC[C@H](C)O.CS(=O)(=O)Cl>>CC(C)=CCC[C@H](C)OS(C)(=O)=O,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20040198814A1,CCOC(=O)C(C)(C)CCCCBr.Cc1ccc(C(C)(CO)CCCCBr)cc1>>CC(C)(CO)CCCCBr,,ClCCl,,CO,[BH4-].[Li+],test
US05593982,Cc1ccc(S(=O)(=O)OCCO[C@H]2CC[C@]3(C)[C@H]4CC[C@]5(C)[C@@H](c6ccoc6)CC[C@]5(O)[C@@H]4CC[C@@H]3C2)cc1.NCCN1CCCC1>>C[C@]12CC[C@H](OCCNCCN3CCCC3)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](c3ccoc3)CC[C@]12O,,CCO,,O,,test
US04000296,CSC(=N)NS(=O)(=O)c1ccccc1.Cc1nc[nH]c1CSCCN>>Cc1nc[nH]c1CSCCNC(=N)NS(=O)(=O)c1ccccc1,,CC#N,,,,test
US06756370B1,CC(O)(c1ccc(F)cc1)C1CCNCC1.ClCCc1ccc(Cl)s1>>CC(O)(c1ccc(F)cc1)C1CCN(CCc2ccc(Cl)s2)CC1,,CC#N,,Cl,O=C([O-])O.[Na+],test
US20150329497A1,C=O.COc1ccccc1NCCNc1c(OC)c(OC)cc2nc(C3CC3)ncc12>>COc1ccccc1N(C)CCNc1c(OC)c(OC)cc2nc(C3CC3)ncc12,CC(=O)O,CO,,[BH3-]C#N.[Na+],,test
US04513001,CC(=O)CCn1cnc2ccccc21.N>>CC(N)CCn1cnc2ccccc21,[Ni],CCOC(C)=O,,,,test
US20100152187A1,COC(=O)c1cnc(N)s1.O=C(Cl)c1ccccc1>>COC(=O)c1cnc(NC(=O)c2ccccc2)s1,CN(C)c1ccncc1,CN(C)C=O,,c1ccncc1,,test
US20150232460A1,CB(O)O.CC(C)(C)OC(=O)N[C@H]1CCC[C@@H]1Nc1ncc(C(F)(F)F)cc1Br>>Cc1cc(C(F)(F)F)cnc1N[C@H]1CCC[C@@H]1NC(=O)OC(C)(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US20090291940A1,Cc1cc(Cl)cc(Cl)[n+]1[O-].N[C@@H]1CN(C(=O)Cc2ccc(OC(F)(F)F)cc2)C[C@H]1O>>Cc1cc(Cl)cc(N[C@@H]2CN(C(=O)Cc3ccc(OC(F)(F)F)cc3)C[C@H]2O)n1,,CCCCO,,,,test
US20130059834A1,CC(C)(C)OC(=O)n1nc(I)c2cc(OC(F)F)ccc21>>FC(F)Oc1ccc2[nH]nc(I)c2c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US06392104B1,CC(=O)Cl.NC12CC3CC(C1)CC(O)(C3)C2>>CC(=O)NC12CC3CC(CC(O)(C3)C1)C2,,C1CCOC1,CN(C)C=O,CCN(CC)CC,,test
US05051434,CNC.CSC(=N[N+](=O)[O-])NCc1ccc(Cl)nc1>>CN(C)C(=N[N+](=O)[O-])NCc1ccc(Cl)nc1,,CCO,,,,test
US04927822,CC(=O)SCCC(=O)Cl.CCOC(=O)C1NN=C(c2ccccc2)S1>>CCOC(=O)C1SC(c2ccccc2)=NN1C(=O)CCSC(C)=O,,Cc1ccccc1,,,,test
US20150210720A1,CC1(C#N)CCC(=O)CC1=O.CCOC(=O)C(=O)CBr>>CCOC(=O)c1coc2c1C(=O)C(C)(C#N)CC2,,CCO,,O=C([O-])O.[Na+],,test
US20160257951A1,C1=COCCC1.CCCCCCCCCCC(CCCCCCC/C=C\C[C@H](O)CCCCCC)OC(=O)OCCCN(C)C>>CCCCCCCCCCC(CCCCCCC/C=C\C[C@@H](CCCCCC)OC1CCCCO1)OC(=O)OCCCN(C)C,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20040176401A1,CNS(C)(=O)=O.COC(=O)c1c(-c2ccc(F)cc2)nc(OS(=O)(=O)c2ccc(C)cc2)nc1C(C)C>>COC(=O)c1c(-c2ccc(F)cc2)nc(N(C)S(C)(=O)=O)nc1C(C)C,,O,,CC#N,,test
US20050165063A1,CCCN(CCC)CCCCN(C)C(=O)c1ccc(CNCc2ncc[nH]2)cc1.Cn1ccnc1C=O>>CCCN(CCC)CCCCN(C)C(=O)c1ccc(CN(Cc2ncc[nH]2)Cc2nccn2C)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20120121509A1,CI.Sc1nc2ccccc2o1>>CSc1nc2ccccc2o1.[I-],,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080214654A1,CC(C)(C)OC(=O)NCCN.COc1cc(C=O)ccc1OCc1ccccc1F>>COc1cc(CNCCNC(=O)OC(C)(C)C)ccc1OCc1ccccc1F,,CO,,O,[BH4-].[Na+],test
US20130089512A1,C[Si](C)(C)CCOCn1c(=O)n(C2CCOCC2)c2nc(-c3cnc4ccc(F)cn34)ncc21>>O=c1[nH]c2cnc(-c3cnc4ccc(F)cn34)nc2n1C1CCOCC1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US05849710,C1CCNCC1.O=C1Cc2cc(C(=O)CBr)ccc2N1>>O=C1Cc2cc(C(=O)CN3CCCCC3)ccc2N1,,CN(C)C=O,,O,,test
US20060258693A1,Nc1ccc(O)cc1.O=[N+]([O-])c1ccc(C=Cc2nc(Cl)c3cc(F)ccc3n2)o1>>O=[N+]([O-])c1ccc(C=Cc2nc(Nc3ccc(O)cc3)c3cc(F)ccc3n2)o1,,O,,CN(C)C=O,,test
US06329405B1,COc1c(OC)c(=O)c1=O.COc1ccc(C(NCCC2=CCCCC2)c2cccc(N)c2)cc1.COc1ccc(C(NCCC2CCCCC2)c2cccc(N)c2)cc1>>COc1ccc(C(NCCC2CCCCC2)c2cccc(Nc3c(N)c(=O)c3=O)c2)cc1,,CO,,,,test
US05786523,COC(=O)c1ccc2cc(O)c(C(=O)OC)cc2c1.ClCc1ccccc1>>COC(=O)c1ccc2cc(OCc3ccccc3)c(C(=O)OC)cc2c1,,CN(C)C=O,CO,O,O=C([O-])[O-].[K+].[K+],test
US20040132726A1,CO.O=C(Cl)c1cc(Cl)ccc1F>>COC(=O)c1cc(Cl)ccc1F,,ClCCl,,,,test
US06432993B1,Cn1c(CO)nc2c(Oc3ccc(C#N)cc3)cccc21.O=C1SC(Cc2ccc(O)cc2)C(=O)N1C(c1ccccc1)(c1ccccc1)c1ccccc1>>Cn1c(COc2ccc(CC3SC(=O)N(C(c4ccccc4)(c4ccccc4)c4ccccc4)C3=O)cc2)nc2ccc(Oc3ccc(C#N)cc3)cc21,,Cc1ccccc1,,CCCCP(CCCC)CCCC,,test
US20070225365A1,COC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Cc1cc(C(F)(F)F)ccc1I.OB(O)c1cncc2ccccc12>>COC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Cc1cc(C(F)(F)F)ccc1-c1cncc2ccccc12,,Cc1ccccc1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20080292608A1,COC(=O)C(C)(C)Br.Cc1cc(O)ccc1O>>COC(=O)C(C)(C)Oc1ccc(O)cc1C,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05037985,C=CCBr.CC1C2CC3=C(CCC4=C3C=C(Cl)CN=CC41C)N2>>C=CCN1C2=C3CC1C(C)C1(C)C=NCC(Cl)=CC3=C1CC2,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,O,test
US06765008B1,CC(=O)OC(C)=O.Cc1cc(C)c(-n2cc(C)c(C#N)c2N)c(C)c1>>CC(=O)Nc1c(C#N)c(C)cn1-c1c(C)cc(C)cc1C,,CC(=O)O,,,,test
US05308840,CN(C)c1cc(C2OCCO2)ccc1O>>CN(C)c1cc(C=O)ccc1O,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20080176871A1,Cc1cc(C)c(O)c(C)c1.Cc1csc2c(Cl)nc(Cl)nc12>>Cc1cc(C)c(Oc2nc(Cl)nc3c(C)csc23)c(C)c1,,C1CCOC1,O,[H-].[Na+],,test
US20110092505A1,CC(C)(C)OC(=O)N1CCN(c2cc(OS(=O)(=O)C(F)(F)F)cc(-c3ccnc(N(C(=O)OC(C)(C)C)C4CCCCC4)c3)n2)CC1.OB(O)c1cncnc1>>c1ncc(-c2cc(-c3ccnc(NC4CCCCC4)c3)nc(N3CCNCC3)c2)cn1,,COCCOC,,ClCCl,O=C([O-])[O-].[Na+].[Na+],test
US20040248961A1,O=C(O)C1CC(O)CN1c1ccc([N+](=O)[O-])cc1>>O=[N+]([O-])c1ccc(N2CC(O)CC2CO)cc1,,C1CCOC1,,CO,,test
US20080207617A1,COc1cc2c(Oc3ccc([N+](=O)[O-])c(F)c3)ccnc2cc1OCCN1C(C)(C)CCCC1(C)C>>COc1cc2c(Oc3ccc(N)c(F)c3)ccnc2cc1OCCN1C(C)(C)CCCC1(C)C,[Zn],CO,,[Cl-].[NH4+],,test
US20160075711A1,COP(=O)(CC(=O)C1CCCCC1)OC.O=Cc1nc(F)ccc1-c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>O=C(C=Cc1nc(F)ccc1-c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)C1CCCCC1,,C1CCOC1,,[H-].[Na+],,test
US20100286390A1,C[C@H]1[C@H](Nc2cnn(CCN)c(=O)c2Br)C[C@@H]2C[C@H]1C2(C)C.O=C(Cl)c1ccncc1>>C[C@H]1[C@H](Nc2cnn(CCNC(=O)c3ccncc3)c(=O)c2Br)C[C@@H]2C[C@H]1C2(C)C,,ClCCl,,CCN(CC)CC,O,test
US05095013,C=CCOC(=O)N1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)C[C@H]1/C=C/C(N)=O>>C=CCOC(=O)N1C[C@@H](S)C[C@H]1/C=C/C(N)=O,,ClCCl,,CC[SiH](CC)CC,O=C(O)C(F)(F)F,test
US20110028461A1,CC(C)(C)OC(=O)N1[C@H](Cc2ccc([N+](=O)[O-])cc2)CC[C@@H]1[C@H](O[Si](C)(C)C(C)(C)C)c1ccc(Cl)nc1>>CC(C)(C)OC(=O)N1[C@H](Cc2ccc(N)cc2)CC[C@@H]1[C@H](O[Si](C)(C)C(C)(C)C)c1cccnc1,[Pd],CCO,,CC(=O)[O-].[K+],,test
US20120202785A1,Nc1ccncc1.O=[N+]([O-])c1ccc(F)cc1F>>O=[N+]([O-])c1ccc(F)cc1Nc1ccncc1,,C1CCOC1,,[Cl-].[NH4+],CC(C)(C)[O-].[K+],test
US20140024694A1,C[C@@H](N)c1cccc(C#N)c1.C[Si](C)(C)C#Cc1c(F)ccc(C#N)c1C#N>>C[C@H](c1cccc(C#N)c1)n1ccc2c(C#N)c(C#N)ccc21,,CN1CCCC1=O,,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US20080227724A1,CCCCCCC/C=C/CBr.COC(=O)C(C)C>>CCCCCCC/C=C/CC(C)(C)C(=O)OC,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20100273850A1,NCCc1ccc(Cl)cc1.O=C(O)c1ccc2[nH]ncc2c1>>O=C(NCCc1ccc(Cl)cc1)c1ccc2[nH]ncc2c1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030069297A1,CCN(CC)CCCNC(=O)c1c(C)[nH]c(C=O)c1C.O=C1Cc2c(cccc2-c2ccc(F)cc2)N1>>CCN(CC)CCCNC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3cccc(-c4ccc(F)cc4)c32)c1C,C1CCNCC1,CCO,,,,test
US20060194969A1,CCOC(=O)c1cc(NCc2c(C)cccc2C)c2nc(C)n(COCc3ccccc3)c2c1>>Cc1cccc(C)c1CNc1cc(C(=O)O)cc2c1nc(C)n2COCc1ccccc1,,C1COCCO1,,Cl,[Na+].[OH-],test
US20070112037A1,CC(=O)OCCc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc([N+](=O)[O-])cc2)cc1>>CC(=O)OCCc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(N)cc2)cc1,[Fe],CCO,O,[Cl-].[NH4+],,test
US04996216,ClCc1cc(C2CC2)no1.Oc1ccc(Oc2cccc(Cl)n2)cc1>>Clc1cccc(Oc2ccc(OCc3cc(C4CC4)no3)cc2)n1,,CN(C)C=O,,[H][H],[H-].[Na+],test
US20100179150A1,CCOC(=O)CC(C)=O.COC(CC(C)=O)OC.O=N[O-]>>CCOC(=O)c1ccc(C)[nH]1,[Zn],CCCCCCC,,CC(=O)O,,test
US20080207721A1,NNc1ccccn1.O=Cc1cc(I)ccc1F>>Ic1ccc2c(cnn2-c2ccccn2)c1,,CN1CCCC1=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100130545A1,COc1cccc2nc(CCN(C)C(=O)OC(C)(C)C)[nH]c12>>CNCCc1nc2cccc(OC)c2[nH]1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20090253699A1,CCOC(=O)c1cccc(-c2ncc(-c3ccc(C(C)C)cc3)s2)c1>>CC(C)c1ccc(-c2cnc(-c3cccc(C(=O)O)c3)s2)cc1,,CO,O,[Li+].[OH-],,test
US20090012151A1,COc1ccc(F)cc1-c1ccc(C(=O)N2CCCC2(C)C)c(Cl)c1>>CC1(C)CCCN1C(=O)c1ccc(-c2cc(F)ccc2O)cc1Cl,,ClCCl,,BrB(Br)Br,,test
US20110207711A1,C#Cc1cnn2cc(-c3cnn(C)c3)cc(OC)c12.Cc1c(I)cnn1-c1ccccc1>>COc1cc(-c2cnn(C)c2)cn2ncc(C#Cc3cnn(-c4ccccc4)c3C)c12,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US04789680,OCc1ccccc1C(F)(F)F.[N-]=[N+]=N>>[N-]=[N+]=NCc1ccccc1C(F)(F)F,,Cc1ccccc1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US03970754,Cn1[nH]c(-c2ccccc2)cc1=O.O=P(Cl)(Cl)Cl>>Cn1nc(-c2ccccc2)cc1Cl,,O,,,,test
US05382600,COS(=O)(=O)OC.O=C1CC(c2ccccc2)c2cc(Cl)ccc2O1.[OH-]>>COc1ccc(Cl)cc1C(CC(=O)O)c1ccccc1,,O,,Cl,,test
US20090036453A1,C[Si](C)(C)C#CC(Oc1cc(Br)ccc1OC(F)F)C1CC1>>C#CC(Oc1cc(Br)ccc1OC(F)F)C1CC1,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20160060282A1,COc1ccccc1CC(C)=O.C[C@H](N)c1ccccc1>>COc1ccc(C[C@H](C)N[C@@H](C)c2ccccc2)cc1,,CO,,O=CO,,test
US20120108619A1,CCOC(=O)c1nn(C(C)(C)C)cc1C=O>>CCOC(=O)c1nn(C(C)(C)C)cc1CO,,CCO,,[BH4-].[Na+],,test
US04330539,CC(=O)O.CN.C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@@H](O)CC[C@@]43C)[C@@H]1C[C@@H](O)C2=O>>CN[C@H]1[C@H](O)C[C@H]2[C@@H]3CC[C@H]4C[C@@H](OC(C)=O)CC[C@]4(C)[C@H]3CC[C@]12C,,CCO,,CC(=O)O,,test
US04235924,C[Si](C)(C)Cl.C[Si](C)(C)N[Si](C)(C)C.O=C1CC(O)C=C1/C=C\CCCCC1OCCOC1O>>C[Si](C)(C)OC1C=C(/C=C\CCCCC2OCCOC2O[Si](C)(C)C)C(=O)C1,,Cc1ccccc1,,c1ccncc1,,test
US20130231328A1,CC(C)(C)[Si](C)(C)Cl.N#CC(O)C[C@H]1CCc2sc3ncnc(OC4CCC(N5CCOCC5)CC4)c3c21>>CC(C)(C)[Si](C)(C)OC(C#N)C[C@H]1CCc2sc3ncnc(OC4CCC(N5CCOCC5)CC4)c3c21,CN(C)c1ccncc1,ClCCl,O,c1c[nH]cn1,,test
US20080146590A1,CC(C)Oc1nn(C(=O)O)c2nc(Oc3ccc(F)cc3F)ncc12>>CC(C)Oc1n[nH]c2nc(Oc3ccc(F)cc3F)ncc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100075964A1,COC(=O)Cc1ccc(-c2ccc(-c3nc(C(F)(F)F)cn3-c3ccccc3Cl)s2)c(C)c1>>Cc1cc(CC(=O)O)ccc1-c1ccc(-c2nc(C(F)(F)F)cn2-c2ccccc2Cl)s1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20130217671A1,CC(C)(C)OC(=O)N[C@H]1CCCN(c2ccc(Nc3c(C(=O)C4CC4)cnc4ccc(-c5cc(Cl)c(O)c(Cl)c5)cc34)cn2)C1.Cl>>Cl.N[C@H]1CCCN(c2ccc(Nc3c(C(=O)C4CC4)cnc4ccc(-c5cc(Cl)c(O)c(Cl)c5)cc34)cn2)C1,,CCOC(C)=O,,,,test
US20150197511A1,CC(=O)c1cc([N+](=O)[O-])cc(C(F)(F)F)c1>>CC(O)c1cc([N+](=O)[O-])cc(C(F)(F)F)c1,,CO,,Cl,[BH4-].[Na+],test
US20130012526A1,Clc1ccc(Sc2oc(C3CCOCC3)nc2Br)cc1.O=C=O>>O=C(O)c1nc(C2CCOCC2)oc1Sc1ccc(Cl)cc1,,C1CCOC1,,[Li]CCCC,,test
US20110144091A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.O=C(N[C@@H]1CCc2ccccc2NC1=O)OCc1ccccc1>>O=C(NC1CCc2ccccc2NC1=S)OCc1ccccc1,,Cc1ccccc1,,,,test
US20140112945A1,COc1ccc(C2=NN(C3CCN(C(=O)[C@@H](Cc4ccc(F)c(F)c4)NC(=O)OC(C)(C)C)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC.Cl>>COc1ccc(C2=NN(C3CCN(C(=O)[C@H](N)Cc4ccc(F)c(F)c4)CC3)C(=O)[C@@H]3CCCC[C@H]23)cc1OC.Cl,,C1COCCO1,,CCOCC,,test
US20130267521A1,CN.C[C@H](NC(=O)c1nccnc1Br)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1>>CNc1nccnc1C(=O)N[C@@H](C)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1,,C1COCCO1,,CCN(C(C)C)C(C)C,Cl,test
US20150336979A1,CC(C)(C)[Si](C)(C)O[C@@H]1CO[C@@H]2[C@@H](N(Cc3ccccc3)C(=O)NC3CCCCC3)CO[C@H]12>>O=C(NC1CCCCC1)N(Cc1ccccc1)[C@H]1CO[C@@H]2[C@H](O)CO[C@H]12,,C1COCCO1,O,Cl,[Na+].[OH-],test
US20130096149A1,CCCS(=O)(=O)Nc1cc(F)cc(-c2nc(C(C)(C)C)sc2-c2ccnc(S(C)(=O)=O)n2)c1Cl>>CCCS(=O)(=O)Nc1cc(F)cc(-c2nc(C(C)(C)C)sc2-c2ccncn2)c1Cl,,CCO,ClCCl,[BH4-].[Na+],,test
US20160244437A1,COCCOCCOCCNC(=O)c1ccc(C)c(-c2cccc(C[C@H](NC(=O)[C@@H]3CC[C@@H](CNC(=O)OC(C)(C)C)CC3)C(=O)Nc3ccc(-c4nnn[nH]4)cc3)c2)c1.Cl>>COCCOCCOCCNC(=O)c1ccc(C)c(-c2cccc(C[C@H](NC(=O)[C@@H]3CC[C@@H](CN)CC3)C(=O)Nc3ccc(-c4nnn[nH]4)cc3)c2)c1.Cl,,C1COCCO1,,CC#N,,test
US03933497,O=S(=O)(O)O.[N-]=[N+]=Nc1cccc2cccc(N)c12>>[N-]=[N+]=Nc1cccc2cccc(O)c12,,O,,O=N[O-].[Na+],,test
US20120283261A1,CN1CCN(Cc2ccc(N)cc2)CC1.Nc1cc(-c2ccc(F)c(Cl)c2)nc(Cl)n1>>CN1CCN(Cc2ccc(Nc3nc(N)cc(-c4ccc(F)c(Cl)c4)n3)cc2)CC1,,CO,ClCCl,,,test
US20050148792A1,N.O=CC1(CC(=O)OCc2ccccc2)CCCCC1>>NCC1(CC(=O)O)CCCCC1,[Pd],CCO,,[H][H],,test
US04513005,C1=COCCC1.O=S(=O)(CC=Cc1ccccc1)CCCO>>O=S(=O)(CC=Cc1ccccc1)CCCOC1CCCCO1,,ClCCl,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20120238564A1,CSc1nccc(-c2cnc3c(Cl)nccn23)n1.NCCN1CCOCC1>>CSc1nccc(-c2cnc3c(NCCN4CCOCC4)nccn23)n1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20100234386A1,CN(C)S(=O)(=O)C1CCNCC1.ClN1CC=Nc2cc(Br)ccc21>>CN(C)S(=O)(=O)C1CCN(c2cnc3ccc(Br)cc3n2)CC1,,CN(C)C=O,,O,[H-].[Na+],test
US20020137750A1,COC(=O)c1ccccc1C1C=CCC1>>COC(=O)c1ccccc1C1CCCC1,[Pd],CCO,,[H][H],,test
US20040132710A1,Fc1ccccn1.O=C1CC[C@](CC2OCCO2)(c2ccc(Cl)c(Cl)c2)CN1>>O=C1CC[C@](CC2OCCO2)(c2ccc(Cl)c(Cl)c2)CN1c1ccccn1,,COCCOC,,CC(C)(C)[O-].[K+],,test
US05292760,CNC(Cc1ccccc1N)c1ccsc1C.O=C1CCC(=O)N1Br>>CNC(Cc1cc(Br)ccc1N)c1ccsc1C,,CN(C)C=O,,,,test
US20110309345A1,Brc1ccc2[nH]c3ccccc3c2c1.ClCc1ccccc1>>Brc1ccc2c(c1)c1ccccc1n2Cc1ccccc1,,C1CCOC1,,O,O=C([O-])[O-].[K+].[K+],test
US20100168430A1,CI.O=C(Nc1ccc(Oc2ccnc3[nH]ncc23)cc1)Nc1ccc(CCF)c(C(F)(F)F)c1>>Cn1ncc2c(Oc3ccc(NC(=O)Nc4ccc(CCF)c(C(F)(F)F)c4)cc3)ccnc21,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20120277440A1,CN=C=O.ON=C1SCCN1Cc1ccc(Cl)nc1>>CNC(=O)ON=C1SCCN1Cc1ccc(Cl)nc1,,CC#N,,,,test
US20150197511A1,COCC(=O)Nc1cc([N+](=O)[O-])cc(C(F)(F)F)c1>>COCC(=O)Nc1cc(N)cc(C(F)(F)F)c1,[Pd],CO,,,,test
US20150238558A1,COC[C@H](N)c1ccccc1.O=Cc1ccc2[nH]ccc2c1>>COC[C@@H](NCc1ccc2[nH]ccc2c1)c1ccccc1,,ClCCCl,,O=C([O-])O.[Na+],,test
US20100168005A1,CCOC(=O)c1cnc(CC(C)C)c(C)c1.N>>Cc1cc(C(N)=O)cnc1CC(C)C,,CO,,,,test
US05656573,CCOC(=O)c1ccc(Br)c(OC)c1Br.CS>>CCOC(=O)c1ccc(Br)c(OC)c1SC,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20070167452A1,[N-]=[N+]=NC[C@@H]1CC[C@H](OCc2ccccc2)CC1>>NC[C@@H]1CC[C@H](OCc2ccccc2)CC1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20130116246A1,C[C@H]1CN(C(=O)OC(C)(C)C)CCN1c1ccc(Nc2cc(Cl)nn(C)c2=O)nc1>>C[C@H]1CNCCN1c1ccc(Nc2cc(Cl)nn(C)c2=O)nc1,,CCO,Cl,,,test
US20040157804A1,C=CCOc1c2c(c(OCOC)c3ncccc13)C(=O)N(Cc1ccc(F)cc1)C2=O>>C=CCOc1c2c(c(O)c3ncccc13)C(=O)N(Cc1ccc(F)cc1)C2=O,,ClCCl,,O=C(O)C(F)(F)F,,test
US06218128B1,C1CCOC1.CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2ccc(C)cc2)=CCC3(C)C)cc1>>CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(c2ccc(O)cc2)=CCC3(C)C)cc1,,CCOC(C)=O,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20140038999A1,Cc1nccc2c1c(=O)n(C)c1cc(Cl)ccc21.O=[Se]=O>>Cn1c(=O)c2c(C=O)nccc2c2ccc(Cl)cc21,,CC(=O)O,ClCCl,,,test
US20010016579A1,CN1CCN(c2nc3cc(Cl)c(N)cc3o2)CC1.O=Cc1ccccc1>>CN1CCN(c2nc3cc(Cl)c(N=Cc4ccccc4)cc3o2)CC1,,Cc1ccccc1,,,,test
US20130289308A1,COc1ccc2c(c1)C(CCNC(C)=O)CC=C2Cl>>COc1ccc2cccc(CCNC(C)=O)c2c1,,CC(C)(C)O,,Cl,CC(C)(C)[O-].[K+],test
US20080081812A1,CC(C)(C)c1nnc(-c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C=C(Br)Br)o1>>C#Cc1c(-c2nnc(C(C)(C)C)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US20150232452A1,CCn1cc(-c2cccc(N)c2)c(-c2ccncc2)n1.O=C=Nc1ccc(C(F)(F)F)cc1>>CCn1cc(-c2cccc(NC(=O)Nc3ccc(C(F)(F)F)cc3)c2)c(-c2ccncc2)n1,,ClCCl,,,,test
US20120129840A1,CC(C)(C)CN.CCCC(C(=O)OC)c1c(C)nc(Cl)nc1-c1ccc(C)cc1>>CCCC(C(=O)OC)c1c(C)nc(NCC(C)(C)C)nc1-c1ccc(C)cc1,,CC(C)O,,,,test
US20040152646A1,COc1ccc(Cl)cc1[C@]1(F)C(=O)N(COC2O[C@H](COCc3ccccc3)[C@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)c2cc(C(F)(F)F)ccc21>>COc1ccc(Cl)cc1[C@]1(F)C(=O)N(COC2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c2cc(C(F)(F)F)ccc21,O=[Pt],CCOC(C)=O,,CCO,,test
US20120010271A1,NCCCCO.O=C(OCC1c2ccccc2-c2ccccc21)N1CCC[C@H]1CO.On1nnc2ccccc21>>O=C(O)[C@@H]1CCCN1.O=C([N-]O)OCC1c2ccccc2-c2ccccc21,,CC#N,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US20140309207A1,CCOC(=O)CC(=O)N1CCC2(C1)CN(C(=O)Nc1ncc(Cl)s1)c1ccc(Cl)cc12>>O=C(CCO)N1CCC2(C1)CN(C(=O)Nc1ncc(Cl)s1)c1ccc(Cl)cc12,,C1CCOC1,CO,[BH4-].[Na+],[Cl-].[NH4+],test
US20100324030A1,O=C(OCc1ccccc1)N1CCNCC1.O=C1COc2ccc(C(=O)CCl)cc2N1>>O=C1COc2ccc(C(O)CN3CCN(C(=O)OCc4ccccc4)CC3)cc2N1,,CC#N,CCO,CCN(CC)CC,,test
US20090221555A1,CC(C)(C)OC(=O)NCCO.COC(=O)c1ccc([N+](=O)[O-])cc1O>>COC(=O)c1ccc([N+](=O)[O-])cc1OCCNC(=O)OC(C)(C)C,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130172384A1,CC1(C)OB(c2ccc3occc3c2)OC1(C)C.Cc1cc(Br)ccc1-c1n[nH]c(=O)n1C[C@@H]1CCN(C(=O)C2CC2)C1>>Cc1cc(-c2ccc3occc3c2)ccc1-c1n[nH]c(=O)n1C[C@@H]1CCN(C(=O)C2CC2)C1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],O=C([O-])O.[Na+],test
US06248739B1,CN1CCC(=O)CC1.Nc1ccc(CN2CCOCC2)cc1>>CN1CCC(Nc2ccc(CN3CCOCC3)cc2)CC1,,CC(=O)O,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130261130A1,COC(=O)c1ccc(NC(=O)c2sc3ccccc3c2Cl)c(O)c1.Clc1ccc(CBr)cc1>>COC(=O)c1ccc(NC(=O)c2sc3ccccc3c2Cl)c(OCc2ccc(Cl)cc2)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20080312270A1,CCOC(=O)Cc1ccc(Oc2ccc3ncccc3c2[N+](=O)[O-])c(OC)c1>>CCOC(=O)Cc1ccc(Oc2ccc3ncccc3c2N)c(OC)c1,[Pd],CCO,,,,test
US04065473,COc1ccc(CCCN)cc1OC.O=C1OC(=O)c2ccccc21>>COc1ccc(CCCN2C(=O)c3ccccc3C2=O)cc1OC,,CC(=O)O,,,,test
US20150111870A1,COc1nc2ccc(Br)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1.Cn1cncc1C(=O)c1ccnc(C(F)(F)F)c1>>COc1nc2ccc(C(O)(c3ccnc(C(F)(F)F)c3)c3cncn3C)cc2c(Cl)c1CN1CCC(C(F)(F)F)CC1,,C1CCOC1,,[Li]CCCC,,test
US20140378634A1,Nc1ccccc1S.Oc1c(Br)cc(Br)cc1CBr>>NSc1ccccc1Cc1cc(Br)cc(Br)c1O,,C1CCOC1,,CCN(CC)CC,,test
US20120028961A1,CC(C)CC(=O)c1ccc(CN=[N+]=[N-])cn1.Cl>>CC(C)CC(O)c1ccc(CN)cn1.Cl,[Pd],CCO,,,,test
US20120244073A1,Nc1ccccc1Oc1ccccc1.O=Cc1cccc2c1OCO2>>c1ccc(Oc2ccccc2NCc2cccc3c2OCO3)cc1,,O=CO,,CO,[BH4-].[Na+],test
US20060154928A1,CCCCCCCCCCCC=O.Cl.N=C(N)NC(=N)NCc1ccccc1>>CCCCCCCCCCCC1N=C(N)NC(NCc2ccccc2)=N1.Cl,,CCO,,Cl,,test
US20020045777A1,CCOC(=O)C=C[C@@H]1CC[C@@H](N(C)C(=O)OC(C)(C)C)CC1>>CCOC(=O)CC[C@@H]1CC[C@@H](N(C)C(=O)OC(C)(C)C)CC1,[Pd],,,,,test
US20110257100A1,O=C1CCC(=O)N1Cc1ccc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)nc1>>Nc1ccc(Oc2ccnc3cc(-c4ccc(CN5C(=O)CCC5=O)cn4)sc23)c(F)c1,[Zn],CO,O,[Cl-].[NH4+],,test
US20140024690A1,CC(C)C(=O)C(=[N+]=[N-])P(=O)([O-])[O-].COc1cccc(C=O)c1F>>C#Cc1cccc(OC)c1F,,CO,,O=C([O-])[O-].[K+].[K+],,test
US20090074738A1,CC(=O)OC[C@H]1O[C@@H](c2cn(Cc3ccc(OCCOS(C)(=O)=O)cc3)c3c(Cl)cccc23)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O.[N-]=[N+]=[N-]>>NCCOc1ccc(Cn2cc([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c3cccc(Cl)c32)cc1,,CN(C)C=O,,O,,test
US20130053581A1,CCCCC[C@@H](/C=C/[C@H]1[C@H](O[Si](C)(C)C(C)(C)C)C[C@H](COS(C)(=O)=O)[C@@H]1Cc1cccc(OCc2ccccc2)c1)O[Si](C)(C)C(C)(C)C>>CCCCC[C@@H](/C=C/[C@H]1[C@H](O[Si](C)(C)C(C)(C)C)C[C@H](COS(C)(=O)=O)[C@@H]1Cc1cccc(O)c1)O[Si](C)(C)C(C)(C)C,[Pd],CO,,[K+].[OH-],,test
US20150315197A1,CC(C)(C)OC(=O)N1CCC(c2cccc(F)c2Cl)CC1.Cl>>Cl.Fc1cccc(C2CCNCC2)c1Cl,,CCOCC,ClCCl,,,test
US20150025054A1,CC(C)(C)OC(=O)N1CCC(N[C@H]2C[C@@H]2c2ccccc2)CC1.Cl>>Cl.c1ccc([C@H]2C[C@@H]2NC2CCNCC2)cc1,,C1COCCO1,,,,test
US05753679,O=C(Cl)c1ccccc1[N+](=O)[O-].OC1CCN(Cc2ccccc2)CC1>>O=C(OC1CCN(Cc2ccccc2)CC1)c1ccccc1[N+](=O)[O-],,Cc1ccccc1,,CCN(CC)CC,,test
US20060237368A1,CCCCCC(CO)CCC.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCCCCC(CCC)COS(=O)(=O)C(F)(F)F,,ClCCl,,O=C([O-])O.[Na+],,test
US20040229958A1,C=CC=O.CC(C)n1cc(-c2ccc(F)cc2)c2ccccc21>>CC(C)n1c(C=CC=O)c(-c2ccc(F)cc2)c2ccccc21,,CC#N,,O,,test
US20110212918A1,COc1ccc(S(=O)(=O)Nc2ccc3c(c2)B(O)OC3)c([N+](=O)[O-])c1>>O=[N+]([O-])c1cc(O)ccc1S(=O)(=O)Nc1ccc2c(c1)B(O)OC2,,ClCCl,,BrB(Br)Br,O,test
US06177440B1,COC(=O)c1cccc2c1c1c(O)cccc1n2Cc1cc(C)cc(C)c1.[NH4+]>>Cc1cc(C)cc(Cn2c3cccc(O)c3c3c(C(N)=O)cccc32)c1,,C1CCOC1,CCOC(C)=O,Cl,,test
US05332717,CO.O=C1OC(O)c2cccc(O)c21>>COC1OC(=O)c2c(O)cccc21,O=S(=O)(O)O,,,,,test
US20120258948A1,CCOC(=O)C(C)(CCn1ccc(I)c(C)c1=O)S(C)(=O)=O.OB(O)c1ccccc1>>CCOC(=O)C(C)(CCn1ccc(-c2ccccc2)c(C)c1=O)S(C)(=O)=O,[Pd],C1COCCO1,,O,O=C([O-])[O-].[K+].[K+],test
US20060276536A1,COCOc1ccc(C=CC(C)=O)cc1OC>>COc1cc(C=CC(C)=O)ccc1O,Cl,CO,,,,test
US20140213581A1,C=CCC1[C@@](CF)(c2cc([N+](=O)[O-])ccc2F)N=C(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(C)(C)S1(=O)=O.O=O>>CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)C1=N[C@](CF)(c2cc([N+](=O)[O-])ccc2F)C(CCCO)S(=O)(=O)C1(C)C,,CO,ClCCl,[BH4-].[Na+],,test
US20070037796A1,CC(C)(C)OC(=O)N(CCCc1ccc([N+](=O)[O-])cc1)CCNS(=O)(=O)c1cc(-c2ccc(O)cc2)cc2cnccc12.Cl.ClCCl>>Cl.Cl.O=[N+]([O-])c1ccc(CCCNCCNS(=O)(=O)c2cc(-c3ccc(O)cc3)cc3cnccc23)cc1,,CO,ClCCl,,,test
US20160106711A1,COc1ccc([Mg]Br)cc1.O=C1Nc2ccccc2C1=O>>COc1ccc(C2(O)C(=O)Nc3ccccc32)cc1,,C1CCOC1,,,,test
US20030220381A1,Cc1oc(-c2ccccc2)nc1CCCC#C[Si](C)(C)C>>C#CCCCc1nc(-c2ccccc2)oc1C,,CO,,[K+].[OH-],,test
US20100239526A1,COc1ccc(Cn2ncc3c4c(cnc32)CNCC4)cc1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COc1ccc(Cn2ncc3c4c(cnc32)CN(C(=O)Cl)CC4)cc1,,C1CCOC1,,CCN(CC)CC,,test
US20100249099A1,C=CS(=O)(=O)N1CCN(C(=O)OCc2ccccc2)CC1.CNC>>CN(C)CCS(=O)(=O)N1CCN(C(=O)OCc2ccccc2)CC1,,C1CCOC1,O,,,test
US20140221333A1,CC(=O)OC(C)=O.NCc1nccnc1Cl>>CC(=O)NCc1nccnc1Cl,,ClCCl,,CCN(CC)CC,Cl,test
US20110245241A1,Cn1c(C2N=C3N(CCOC3(C)C)C(=O)C2(O)OCc2ccccc2)nc(Cl)c1Cc1ccc(F)cc1>>Cn1c(Cc2ccc(F)cc2)cnc1-c1nc2n(c(=O)c1O)CCOC2(C)C,[Pd],CCO,,O=C[O-].[NH4+],,test
US04188489,C=CC(=O)OOC(C)(N)CC.CCN=C=O>>C=CC(=O)OOC(C)(CC)NC(=O)NCC,,CC#N,,,,test
US04957927,Fc1ccc(C(Br)c2ccc(F)cc2)cc1.OCCBr>>Fc1ccc(C(OCCBr)c2ccc(F)cc2)cc1,,O,,O=C([O-])[O-].[Na+].[Na+],,test
US20110039829A1,CC(C)(C)OC(=O)CC[C@H](N)C(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1.O=C(O)c1cc(O)n(-c2ccccc2)n1>>CC(C)(C)OC(=O)CC[C@H](NC(=O)c1cc(O)n(-c2ccccc2)n1)C(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1,,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,On1nnc2ccccc21,test
US20110172297A1,CC(C)S(=O)(=O)Cl.N[C@@H]1CCOC[C@H]1c1ccc(I)cc1>>CC(C)S(=O)(=O)N[C@@H]1CCOC[C@H]1c1ccc(I)cc1,,ClCCl,,C1CCC2=NCCCN2CC1,,test
US20100261755A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.Fc1cc(Br)ccc1C(F)(F)F>>CC1(C)OB(c2ccc(C(F)(F)F)c(F)c2)OC1(C)C,Cl[Pd]Cl,CCOC(C)=O,CS(C)=O,CC(=O)[O-].[K+],,test
US20070032496A1,CN(C)c1cc[nH]c(=O)c1[N+](=O)[O-].OB(O)c1ccccc1>>CN(C)c1ccn(-c2ccccc2)c(=O)c1[N+](=O)[O-],,ClCCl,,CCN(CC)CC,c1ccncc1,test
US20100216769A1,COCC(N)(CO)COC.O=C(Cl)c1ccc(Cl)s1>>COCC(CO)(COC)NC(=O)c1ccc(Cl)s1,,C1CCOC1,,,,test
US20150361100A1,CC(Nc1ncnc(N)c1C=O)c1cc2ccccn2c1-c1ccccn1.NO>>CC(Nc1ncnc(N)c1/C=N/O)c1cc2ccccn2c1-c1ccccn1,,CCO,,Cl,c1ccncc1,test
US20090163471A1,CC[C@@H](C)Nc1cc(C(=O)OC)c(C(F)(F)F)cc1C#N.OO>>CC[C@@H](C)Nc1cc(C(=O)OC)c(C(F)(F)F)cc1C(N)=O,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20090088425A1,CCOC(=O)c1cnc2ccc(C#N)cc2c1Cl>>CCOC(=O)c1cnc2ccc(C#N)cc2c1,[Pd],CCO,,CCN(CC)CC,,test
US04582854,CC1(C)CC(=O)OC(=O)C1>>CC1(C)CCOC(=O)C1,,C1CCOC1,,[BH4-].[Na+],,test
US20050014759A1,ClCCN1CCOCC1.N#Cc1cc(C(=O)c2cccc(O)c2)n2c1ccc1ccccc12>>N#Cc1cc(C(=O)c2cccc(OCCN3CCOCC3)c2)n2c1ccc1ccccc12,,CC(C)=O,,Cl,O=C([O-])[O-].[K+].[K+],test
US20160009677A1,COc1cccc(CC(C)(C)O)c1.O=C1CCC(=O)N1Br>>COc1ccc(Br)c(CC(C)(C)O)c1,,CC#N,,,,test
US07160901B2,CN(C)CCCl.CS(=O)(=O)Nc1cccc([N+](=O)[O-])c1>>CN(C)CCN(c1cccc([N+](=O)[O-])c1)S(C)(=O)=O,,CS(C)=O,,O,CC(C)(C)[O-].[K+],test
US20110301143A1,CON(C)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1.FC(F)(F)c1ccccc1Br>>CC(C)(C)OC(=O)N1CCC(C(=O)c2ccccc2C(F)(F)F)CC1,,C1CCOC1,,[Li]C(C)(C)C,,test
US20140221343A1,CC(C)(C)OC(=O)NCCBr.CSc1cc2c(cc1Sc1nc3c(N)nccc3[nH]1)OCO2>>CSc1cc2c(cc1Sc1nc3c(N)nccc3n1CCNC(=O)OC(C)(C)C)OCO2,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US06300519B1,CC(C)(C)OC(=O)NN(Cc1ccc(-c2nnn(C(C)(C)c3ccccc3)n2)cc1)C[C@H](O)[C@@H](N)Cc1ccccc1.CC[C@H](C)[C@H](NC(=O)OC)C(=O)O.CN(C)C=O.ClCCCl>>CCCCOC(=O)NN(Cc1ccc(-c2nnn(C(C)(C)c3ccccc3)n2)cc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)OC)[C@@H](C)CC,,CN(C)C=O,,On1nnc2ccccc21,,test
US20080161366A1,Cc1ccc(N2c3ccccc3NS2(=O)=O)c(F)c1.OCCCBr>>Cc1ccc(N2c3ccccc3N(CCCBr)S2(=O)=O)c(F)c1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130026422A1,CC1(C)c2ccccc2-n2c3ccc(Br)cc3c3cc(Br)cc1c32.Cc1ccccc1.OB(O)c1ccccc1>>CC1(C)c2ccccc2-n2c3ccc(-c4ccccc4)cc3c3cc(-c4ccccc4)cc1c32,,CCO,Cc1ccccc1,O=C([O-])O.[Na+],,test
US03935261,CC(C)(O)C#N.O=C1CCC=C1CCCCCCCO>>N#CC1CCC(=O)C1CCCCCCCO,,CO,,O=C([O-])[O-].[Na+].[Na+],,test
US04918094,CI.COC(=O)c1ccc(Cc2c[nH]c3ccc(C(=O)NCC4CCCC4)cc23)c(OC)c1>>COC(=O)c1ccc(Cc2cn(C)c3ccc(C(=O)NCC4CCCC4)cc23)c(OC)c1,,CN(C)C=O,,[H-].[Na+],,test
US20130096144A1,Cn1nccc1-c1ccc2c(c1)CN([C@@H](Cc1cc(F)cc(F)c1)CN1C(=O)c3ccccc3C1=O)C2=O>>Cn1nccc1-c1ccc2c(c1)CN([C@H](CN)Cc1cc(F)cc(F)c1)C2=O,,C1CCOC1,CO,NN,,test
US20080125413A1,COC(=O)[C@H](Cc1ccccc1)NC(=O)NC1CCN(Cc2ccccc2)CC1>>O=c1[nH]c(Cc2ccccc2)cn1C1CCN(Cc2ccccc2)CC1,,Cc1ccccc1,ClCCl,CC(C)C[Al+]CC(C)C.[H-],,test
US20070161686A1,CI.COc1cc(NC(=O)C2CC2)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1>>COc1cc(N(C)C(=O)C2CC2)ccc1-c1nnc(-c2c(-c3ccccc3)noc2C)o1,,CN(C)C=O,,C[Si](C)(C)[N-][Si](C)(C)C.[K+],,test
US05312828,CCCCc1ncc(/C(C)=C/C(=O)OCC)n1Cc1ccccc1Cl>>CCCCc1ncc(/C(C)=C/C(=O)O)n1Cc1ccccc1Cl,,CCOC(C)=O,CO,,,test
US04070539,C=C(CC)C(=O)c1ccc(OCC(=O)O)c(C)c1C>>CCC1Cc2cc(OCC(=O)O)c(C)c(C)c2C1=O,,O=S(=O)(O)O,,,,test
US20130053373A1,CC(C)(C)OC(=O)NC1=N[C@@]2(c3ccccc3F)CO[C@@H](CO)C[C@H]2CS1.CS(=O)(=O)Cl>>CC(C)(C)OC(=O)NC1=N[C@@]2(c3ccccc3F)CO[C@@H](COS(C)(=O)=O)C[C@H]2CS1,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20100130464A1,O=C1c2ccccc2C(=O)N1CCO.OC(c1ccc(Cl)cc1)c1ccc(Br)cc1>>O=C1c2ccccc2C(=O)N1CCOC(c1ccc(Cl)cc1)c1ccc(Br)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20080312232A1,COC(=O)c1cc(Br)cn(-c2ccccc2)c1=O>>O=C(O)c1cc(Br)cn(-c2ccccc2)c1=O,,C1COCCO1,O,Cl,[Na+].[OH-],test
US20140073620A1,CN1CCC(n2cc(N)cn2)CC1.NC(=O)C1(c2ccccc2CCc2nc(Cl)ncc2Cl)CC1>>CN1CCC(n2cc(Nc3ncc(Cl)c(CCc4ccccc4C4(C(N)=O)CC4)n3)cn2)CC1,,CO,,O,,test
US06114334,C=O.COc1ccccc1N1CCNCC1.Nc1cc(C2CC2)nn1-c1ccccc1>>COc1ccccc1N1CCN(Cc2c(C3CC3)nn(-c3ccccc3)c2N)CC1,,,,,,test
US20090312381A1,O=C(NCC(=O)c1ccc(Cl)s1)NCc1ccccc1F>>O=c1[nH]cc(-c2ccc(Cl)s2)n1Cc1ccccc1F,,CO,Cl,,,test
US04526719,COC1=C(OC)C(=O)C(CCCCCCCCCC(=O)Oc2ccc([N+](=O)[O-])cc2)=C(C)C1=O.CSCC[C@H](N)C(=O)O>>COC1=C(OC)C(=O)C(CCCCCCCCCC(=O)N[C@@H](CCSC)C(=O)O)=C(C)C1=O,,CN(C)C=O,,CCN(CC)CC,,test
US20110183947A1,COC(=O)c1cccc(-c2nnc(C(=O)CCc3ccc(-c4ccccc4)cc3)o2)n1>>O=C(O)c1cccc(-c2nnc(C(=O)CCc3ccc(-c4ccccc4)cc3)o2)n1,,CC(=O)O,CCOC(C)=O,,,test
US20110039832A1,CC(C)(C)OC(=O)N1CCCNCC1.O=C(Cl)C1CCC1>>CC(C)(C)OC(=O)N1CCCN(C(=O)C2CCC2)CC1,,ClCCl,,CCN(CC)CC,,test
US20140309228A1,Cc1cc(C(=O)O)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1.NCCN1CCOCC1>>Cc1cc(C(=O)NCCN2CCOCC2)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1,,ClCCl,,On1nnc2ccccc21,,test
US20150197500A1,CC(C)(C)c1cccc(O)c1.O=S(=O)(Cl)Cl>>CC(C)(C)c1cc(O)ccc1Cl,,ClCCl,,,,test
US20050277676A1,NC(=S)c1ccccc1N.O=C(CBr)C1CCC1>>Nc1ccccc1-c1nc(C2CCC2)cs1,Cl,,,,,test
US05387685,COc1cc2c(cc1OC)CNCC2.COc1ccc(C(C#N)(CCCCCBr)Sc2ccccn2)cc1OC>>COc1ccc(C(C#N)(CCCCCN2CCc3cc(OC)c(OC)cc3C2)Sc2ccccn2)cc1OC,,CC#N,,CCN(C(C)C)C(C)C,Cl,test
US20040157836A1,CC1(C)CCc2ccc(N)c(Br)c2C1=O.O=S(=O)(Cl)c1ccccc1F>>CC1(C)CCc2ccc(NS(=O)(=O)c3ccccc3F)c(Br)c2C1=O,,ClCCl,,c1ccncc1,,test
US20110178200A1,COc1ccc2cc(Br)ccc2c1.II>>COc1ccc2cc(I)ccc2c1,,C1CCOC1,,O,[Li]CCCC,test
US05075303,CCCNO.Clc1ccnc2c1CCC=C2>>CCCN(O)C1CCc2c(Cl)ccnc2C1,,CO,,Cl,,test
US20060025350A1,CC(=O)O[C@H]1[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H](O[C@@H]2[C@@H](COCc3ccccc3)N(C(=O)OCc3ccccc3)C[C@H]2OCc2ccccc2)O[C@@H]1COCc1ccccc1>>O=C(OCc1ccccc1)N1C[C@@H](OCc2ccccc2)[C@H](O[C@H]2O[C@H](COCc3ccccc3)[C@@H](O)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)[C@H]1COCc1ccccc1,,CCOC(C)=O,CO,O=C([O-])[O-].[K+].[K+],,test
US20090099156A1,C1C[C@@H](CN2CCNCC2)CN(C2CC2)C1.CC(C)(C)c1cc(NC(=O)Oc2ccccc2)no1.CCN(CC)CC>>CC(C)(C)c1cc(NC(=O)N2CCN(C[C@@H]3CCCN(C4CC4)C3)CC2)no1.N,,C1CCOC1,,,,test
US04944795,C=C(F)C(C)(C)C(=O)OCC>>C=C(F)C(C)(C)C(=O)O,,CCO,O,[K+].[OH-],,test
US20120316194A1,Cn1ccc2cnc(NC(=O)c3ccc([C@@](C)(O)CO)cc3)cc21.O=C1CCC(=O)N1Cl>>Cn1cc(Cl)c2cnc(NC(=O)c3ccc([C@@](C)(O)CO)cc3)cc21,,CN(C)C=O,,,,test
US20070249580A1,COC(=O)c1ccccc1N1CCCC(CN2C(=O)c3ccccc3C2=O)C1>>COC(=O)c1ccccc1N1CCCC(CN)C1,,CO,O,NN,,test
US04359474,CCOC(CC(OCC)OCC)OCC.NNc1cccc(C(F)(F)F)c1>>FC(F)(F)c1cccc(-n2cccn2)c1,,CCO,,Cl,O,test
US20130287767A1,COC(OC)N(C)C.Cc1[se]c(N)c(C#N)c1-c1ccccc1.Nc1ccc(F)c(Cl)c1>>Cc1[se]c2ncnc(Nc3ccc(F)c(Cl)c3)c2c1-c1ccccc1,,CC(=O)O,Cc1ccccc1,[Br-].[K+],,test
US20020120139A1,OCCCCCCC#Cc1ccc(Cl)c(Cl)c1>>OCCCCCCCCc1ccc(Cl)c(Cl)c1,O=[Pt]=O,CO,,,,test
US20110097305A1,FC1(F)CCC2(C=Cc3cccnc3O2)CC1>>FC1=CCC2(C=Cc3cccnc3O2)CC1,,ClCCl,,O=C([O-])O.[Na+],,test
US20120058984A1,BrB(Br)Br.COc1ccc(CCN)cc1S(N)(=O)=O>>Br.NCCc1ccc(O)c(S(N)(=O)=O)c1,,ClCCl,,CO,,test
US20160130253A1,O=c1cc(Br)c(=O)[nH][nH]1.OB(O)c1ccncc1>>O=c1cc(-c2ccncc2)c(=O)[nH][nH]1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,,O=C([O-])[O-].[Na+].[Na+],,test
US20060009451A1,CN(C)[C@@H]1CCNC1.CS(=O)(=O)OCCc1cc2cc(-c3c4c(nc5ccnn35)CCC4)ccc2o1>>CN(C)[C@@H]1CCN(CCc2cc3cc(-c4c5c(nc6ccnn46)CCC5)ccc3o2)C1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080221043A1,BrC(Br)Br.C1=CC=CCC=C1>>BrC1Cc2ccccc21,,CC(C)=O,,C1COCCOCCOCCOCCOCCO1,O=C([O-])[O-].[K+].[K+],test
US20030109532A1,CC(=O)c1cccc(N2C[C@H](C)N[C@H](C)C2)c1.CCCI>>CCCN1[C@@H](C)CN(c2cccc(C(C)=O)c2)C[C@H]1C,,CO,,ClCCl,,test
US20130310357A1,CC(C)(C)c1cc(NC(=O)Oc2ccccc2)no1.Cc1cc(N)ccc1[N+](=O)[O-]>>Cc1cc(NC(=O)Nc2cc(C(C)(C)C)on2)ccc1[N+](=O)[O-],CN(C)c1ccncc1,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US20140221311A1,COC(=O)CBr.Nc1cnc(-c2ccc(-c3ccccc3O)cc2F)cn1>>COC(=O)COc1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US07074819B2,COCOc1ccc(C2(C)COc3cc(OCOC)ccc3C2(O)C#CCCO[Si](C)(C)C(C)(C)C)cc1>>COCOc1ccc(C2(C)COc3cc(OCOC)ccc3C2CCCCO[Si](C)(C)C(C)(C)C)cc1,[Pd],CCOC(C)=O,,,,test
US20050027121A1,Cc1ccc(C[C@@H]2CN(Cc3cnn(CC(=O)OC(C)(C)C)c3)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C>>Cc1ccc(C[C@@H]2CN(Cc3cnn(CC(=O)O)c3)CCN2C(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1C,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20110015240A1,CC(=O)Nc1nc(CCc2ccc(COC(=O)NNC(=O)OC(C)(C)C)cc2)cs1.Cl>>CC(=O)Nc1nc(CCc2ccc(COC(=O)NN)cc2)cs1.Cl,,ClCCl,,C1COCCO1,,test
US05281747,CC(C)COP(C)(=O)CCC#N>>CC(C)COP(C)(=O)CCCN,[Ni],CCO,,N,[H][H],test
US20120172345A1,C1COCCN1.COC(=O)c1sc(Br)c(C#N)c1C>>COC(=O)c1sc(N2CCOCC2)c(C#N)c1C,,C1CCOC1,,O=C([O-])[O-].[Cs+].[Cs+],,test
US05698692,CCC(CC)(Oc1ccc(CCNC(=O)c2cc3c(s2)CCN(C(=O)OC(C)(C)C)C3)cc1OCC(=O)[O-])C(=O)[O-]>>CC(C)(C)OC(=O)N1CCc2sc(C=O)cc2C1,,ClCCl,,O=[Cr](=O)([O-])Cl.c1cc[nH+]cc1,,test
US20030027800A1,CC(C)(C)OC(=O)N[C@H]1COC1=O.COc1cccc(N)c1>>COc1cccc(NC(=O)C(CO)NC(=O)OC(C)(C)C)c1,,C1CCOC1,,,,test
US20160016908A1,CC(=O)N1c2ccccc2[C@H](NC(=O)OCc2ccccc2)[C@@H](C)[C@@H]1CC(F)(F)F>>CC(=O)N1c2ccccc2[C@H](N)[C@@H](C)[C@@H]1CC(F)(F)F,[Pd],CO,,,,test
US04352818,CI.CN1Cc2c(CO)ncn2-c2cccc(Cl)c2C1=O>>COCc1ncn2c1CN(C)C(=O)c1c(Cl)cccc1-2,,O,,CN(C)C=O,[H-].[Na+],test
US20160096827A1,Cc1cc(N)ccc1C1CCN(C=O)CC1.Clc1ncnc(Cl)n1>>Cc1cc(Nc2ncnc(Cl)n2)ccc1C1CCN(C=O)CC1,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US20110009454A1,Cc1cccc(CCl)c1.Nc1ncccc1C(=O)NCc1cccc(O)c1>>Cc1cccc(COc2cccc(CNC(=O)c3cccnc3N)c2)c1,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20020137961A1,COCOc1ccc(C2CCC3(CC2)OCCO3)c(OCOC)c1>>COCOc1ccc(C2CCC(=O)CC2)c(OCOC)c1,,CO,,Cl,O=C([O-])O.[Na+],test
US20130116232A1,C[C@@H]1CCCN1.OCCBr>>C[C@@H]1CCCN1CCO,,CC#N,,Cl,O=C([O-])[O-].[K+].[K+],test
US03931407,COc1ccc(C(=O)CC2CCCCC2=O)cc1.Nc1ccc(O)c(C(=O)O)c1>>COc1ccc(-c2cc3c(n2-c2ccc(O)c(C(=O)O)c2)CCCC3)cc1,,CC(=O)O,,,,test
US05935990,CC(=O)CCC(=O)c1ccc(S(C)(=O)=O)cc1.Nc1ccccc1>>Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccccc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US05500425,C=CCN(CCC)C1COc2cccc(OS(=O)(=O)C(F)(F)F)c2C1.CN(C)C=O.C[Sn](C)(C)C>>C=CCN(CCC)C1COc2cccc(C(C)=O)c2C1,Cl[Pd]Cl,C1CCOC1,CCCCCC,[Cl-].[Li+],,test
US06566381B1,C=CC(OCc1ccccc1)C(NC(=O)OC(C)(C)C)C(=O)O.CO.O=S(=O)(Cl)c1ccc(Br)cc1>>C=CC(OCc1ccccc1)C(NS(=O)(=O)c1ccc(Br)cc1)C(=O)OC,,CCN(CC)CC,ClCCl,O=S(Cl)Cl,,test
US04864021,ClCc1cccc(Cl)c1.O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1F>>O=c1[nH]c(=O)n([C@H]2C[C@H](OCc3cccc(Cl)c3)[C@@H](CO)O2)cc1F,,C1COCCO1,O,[K+].[OH-],,test
US20100310493A1,C1COCCN1.Nc1ncc(Br)s1>>Nc1ncc(N2CCOCC2)s1,,CN(C)C=O,,Br,O=C([O-])[O-].[K+].[K+],test
US20070105904A1,Fc1ccc(CCl)nc1.Nc1ncc(F)cc1-c1cc(Cc2ccc(O)cc2)no1>>Nc1ncc(F)cc1-c1cc(Cc2ccc(OCc3ccc(F)cn3)cc2)no1,,CN(C)C=O,,C1CCOC1,[Na+].[OH-],test
US20040092598A1,C(=NC1CCCCC1)=NC1CCCCC1.CN(C)c1ccc(C(=O)O)c2ccccc12.ClCCl.O=C(Cl)/C=C/C=C/c1ccccc1.O=C1CCC(=O)N1O>>COC(=O)CCCCNC(=O)c1ccc(N(C)C)c2ccccc12,,ClCCl,,CCN(CC)CC,,test
US20110195948A1,Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3C(F)(F)F)nc12.O=C(n1ccnc1)n1ccnc1.O[C@H]1CCNC1>>O=C(Nc1cnn2ccc(N3CCC[C@@H]3c3cc(F)ccc3C(F)(F)F)nc12)N1CC[C@H](O)C1,,ClCCl,,,,test
US05079260,CCOC(C)=O.COc1ccc2c(c1)Cc1ccccc1-2>>COc1ccc2c(c1)C(C(=O)O)c1ccccc1-2,,C1CCOC1,O,[Li]CCCC,,test
US20090118501A1,C1CCOC1.CNS(=O)(=O)c1cnc(N)s1.C[C@@H]1CC[C@@H](NC2CCCCC2)CC1>>CNS(=O)(=O)c1cnc(NC(=O)N(C2CCCCC2)[C@@H]2CC[C@@H](C)CC2)s1,CN(C)c1ccncc1,,,,,test
US20110245429A1,Brc1ccc(-n2c3ccccc3c3ccccc32)cc1.C1COCCO1.c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1>>COc1ccc(-c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US20070270475A1,CI.COc1cc(C(=O)N2[C@@H](c3ncc(C)s3)[C@@H](CO)C[C@@]2(Cc2cscn2)C(=O)OC(C)(C)C)ccc1C(C)(C)C>>COC[C@H]1C[C@@](Cc2cscn2)(C(=O)OC(C)(C)C)N(C(=O)c2ccc(C(C)(C)C)c(OC)c2)[C@H]1c1ncc(C)s1,,CN(C)C=O,,[H-].[Na+],,test
US05204373,COc1ccc2c(c1)CCC(CO)C2.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COc1ccc2c(c1)CCC(COS(=O)(=O)C(F)(F)F)C2,,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US04013692,CCOC(=O)Cc1oc2cccc-2cc1-c1ccccc1.NN>>NNC(=O)Cc1oc2cccc-2cc1-c1ccccc1,,CCO,,,,test
US05102757,CC(=O)C(=O)c1ccccc1.NC1=C(N)C(=O)c2ccccc2C1=O>>CC1=C(c2ccccc2)C(=O)c2ccccc2C1=O,,CC(=O)O,O,,,test
US20060173041A1,CC(C)(C)OC(=O)N1CCC(O)CC1.Oc1ccc(F)cc1Br>>CC(C)(C)OC(=O)N1CCC(Oc2ccc(F)cc2Br)CC1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US05151440,Nc1cccc2c1CCCC2.O=S(=O)(O)C1=NCCN1>>c1cc2c(c(N=C3NCCN3)c1)CCCC2,,CC#N,,,,test
US20110207704A1,CCOC(=O)/C=C/COc1cccc(-c2nc(-c3ccc(OC(C)C)c(Cl)c3)no2)c1C>>Cc1c(OC/C=C/C(=O)O)cccc1-c1nc(-c2ccc(OC(C)C)c(Cl)c2)no1,,CC(=O)O,,[Na+].[OH-],,test
US20030166628A1,COC(=O)c1cc2c(Br)cccc2s1>>O=C(O)c1cc2c(Br)cccc2s1,,O,,CO,[Na+].[OH-],test
US20160102083A1,CCN(C(=O)OC(C)(C)C)c1scc(C(=O)OC)c1C>>CCNc1scc(C(=O)OC)c1C,,ClC(Cl)Cl,,O=C(O)C(F)(F)F,,test
US20070037809A1,CC(C)(C)OC(=O)N1CCN(Cc2ccc3oc(-c4cccc(N)c4)nc3n2)CC1.CN(C)c1cccc(C(=O)Cl)c1>>CN(C)c1cccc(C(=O)Nc2cccc(-c3nc4nc(CN5CCN(C(=O)OC(C)(C)C)CC5)ccc4o3)c2)c1,,c1ccncc1,,Cl,,test
US06630281B2,C1=CC2CCC1C2.O=C1C=CC(=O)O1.OCC1CC2C=CC1C2>>C1=CC2CCC1C2.O=C1C=CC(=O)O1.OCC1CC2C=CC1C2,,C1CCOC1,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20030153752A1,Nc1ccc(-c2cn(C3CCC4(CC3)OCCO4)c3ncnc(N)c23)cc1Cl>>Nc1ccc(-c2cn(C3CCC(=O)CC3)c3ncnc(N)c23)cc1Cl,,CC(C)=O,,Cl,,test
US20090298818A1,COC(=O)c1ccc2c(c1)CN(Cc1ccccc1)C2>>OCc1ccc2c(c1)CN(Cc1ccccc1)C2,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20050014811A1,COC(=O)N=C(NC(=O)OC)SC.Nc1ccc(OS(=O)(=O)c2ccc(NCC3CC3)cc2)cc1N>>COC(=O)Nc1nc2cc(OS(=O)(=O)c3ccc(NCC4CC4)cc3)ccc2[nH]1,,CC(=O)O,CO,,,test
US20140005168A1,Cc1cncc(-c2cc3c(cn2)cnn3-c2cnc(Cl)c(N3CCC[C@H](NC(=O)OC(C)(C)C)C3)n2)n1>>Cc1cncc(-c2cc3c(cn2)cnn3-c2cnc(Cl)c(N3CCC[C@H](N)C3)n2)n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US05693639,CC(O)(C(=O)O)C(F)(F)F.CN(c1ccccc1)S(=O)(=O)c1ccc(N)cc1>>CN(c1ccccc1)S(=O)(=O)c1ccc(NC(=O)C(C)(O)C(F)(F)F)cc1,,CC(=O)N(C)C,O,O=S(Cl)Cl,,test
US20030139409A1,CN(C)CC(N)Cc1ccccc1.COc1cccc2c1ccc1nc3cccc(C(=O)O)c3nc12>>COc1cccc2c1ccc1nc3cccc(C(=O)NC(Cc4ccccc4)CN(C)C)c3nc12,,CCN(CC)CC,,Cl,,test
US20060223835A1,CC(C)C([C@@H]1C[C@@H](CS(=O)(=O)[O-])C1)C(O[SiH3])(C(C)C)C(C)C.Nc1ncnc2nc[nH]c12>>CC(C)C([C@@H]1C[C@H](n2cnc3c(N)ncnc32)C1)C(O[SiH3])(C(C)C)C(C)C,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20140336190A1,Cc1noc(C)c1-c1cc(C(O)(c2ccccn2)c2nccn2[Si](C)(C)C(C)(C)C)c2nc(C3CC3)[nH]c2c1>>Cc1noc(C)c1-c1cc(C(O)(c2ccccn2)c2ncc[nH]2)c2nc(C3CC3)[nH]c2c1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06096710,CC(C)(C)OC(=O)NCC(=O)O.CCCC[C@H](N)C(=O)OCC>>CCCC[C@H](NC(=O)CNC(=O)OC(C)(C)C)C(=O)OCC,,CN(C)C=O,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US04198415,CI.O=C1CCC2=C(CCC(OC(=O)c3ccccc3)C2)N1>>CN1C(=O)CCC2=C1CCC(OC(=O)c1ccccc1)C2,,C1CCOC1,,[H-].[Na+],,test
US20080312226A1,Nc1cncnc1.O=C(Cl)OCC(Cl)(Cl)Cl>>O=C(Nc1cncnc1)OCC(Cl)(Cl)Cl,,C1CCOC1,,c1ccncc1,,test
US20070208010A1,CI.Cc1nc2n(n1)C(=S)NCC2>>CSC1=NCCc2nc(C)nn21,,[Na+],[OH-],,,test
US06121285,CC(C)(C#N)N=NC(C)(C)C#N.CCOC(=O)/C=C(\C)C1(C(=O)OCC)CCC1.ClC(Cl)Cl.O=C1CCC(=O)N1Br>>CCOC(=O)C1(C2=CC(=O)N([C@@H](C)c3ccccc3)C2)CCC1,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20140057303A1,Cc1cc2c(s1)Nc1ccc(C#N)cc1N=C2N1CCN(C)CC1>>Cc1cc2c(s1)Nc1ccc(CN)cc1N=C2N1CCN(C)CC1,[Pd],CO,,Cl,,test
US05580866,CS(=O)(=O)Cl.c1ccc2c(c1)CNCCS2>>CS(=O)(=O)N1CCSc2ccccc2C1,,ClCCl,,CCN(CC)CC,,test
US20080287479A1,CS(=O)(=O)c1ccc2c(c1)[nH]c(=O)n2C1CCNCC1.O=C(CCl)C1CCCCC1>>CS(=O)(=O)c1ccc2c(c1)[nH]c(=O)n2C1CCN(CC(=O)C2CCCCC2)CC1,,CN(C)C=O,,O=C(O)C(F)(F)F,,test
US20140142074A1,CI.COc1ccc(NC(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1OC>>COc1ccc(N(C)C(=O)O[C@@H](Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1OC,,C1CCOC1,,[H-].[Na+],,test
US04265890,C=CCBr.COc1cc2c(cc1OC)CCNCC2>>C=CCN1CCc2cc(OC)c(OC)cc2CC1,,CC#N,,CCN(CC)CC,,test
US20070191604A1,CC(=O)Nc1nn(C(=O)OC(C)(C)C)c2ccc(NC(=O)C3CCN(CC(=O)N4CCN(c5ccc(-c6ncccn6)cc5)CC4)C3)cc12>>CC(=O)Nc1n[nH]c2ccc(NC(=O)C3CCN(CC(=O)N4CCN(c5ccc(-c6ncccn6)cc5)CC4)C3)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US04970213,CC(C)(C)N.CCOC(=O)C(=CN(C)C)C(=O)c1cc2cc(F)c(F)c(F)c2nc1Cl>>CCOC(=O)c1cn(C(C)(C)C)c2nc3c(F)c(F)c(F)cc3cc2c1=O,,CCO,ClC(Cl)Cl,C1CCC2=NCCCN2CC1,,test
US20150038438A1,COc1ccc(Cn2c3c(c(O)c(C(=O)O)c2=O)CCCc2cc4c(cc2-3)cc(CO)n4C)c(OC)c1>>COc1ccc(Cn2c3c(c(O)c(C(=O)O)c2=O)CCCc2cc4c(cc2-3)cc(C=O)n4C)c(OC)c1,O=[Mn]=O,ClCCl,,,,test
US20130261100A1,CO.O=C(O)c1cc(C(F)(F)F)cnc1Cl>>COC(=O)c1cc(C(F)(F)F)cnc1Cl,,CCOCC,CO,C[Si](C)(C)C=[N+]=[N-],,test
US06114358,CCOC(=O)CCC(C)=O.CCOC(OCC)OCC>>CCOC(=O)CCC(C)(OCC)OCC,Cc1ccc(S(=O)(=O)O)cc1,,,CCO,,test
US20110160198A1,CC(C)(C)OC(=O)N[C@H]1CC[C@@H](C(=O)O)C1.COC(=O)[C@H](Cc1ccc(-c2ccnc(C)c2C)cc1)NC(=O)[C@@H]1Cc2cc3c(cc2CN1)O[C@@H](c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1)CO3>>Cc1nccc(-c2ccc(C[C@H](NC(=O)[C@@H]3Cc4cc5c(cc4CN3C(=O)[C@@H]3CC[C@H](NC(=O)OC(C)(C)C)C3)O[C@@H](c3ccc(OCc4ccc(Cl)c(Cl)c4)cc3)CO5)C(=O)O)cc2)c1C,,ClCCl,,ClCCCl,,test
US20040002495A1,CN1C(=O)[C@H](NC(=O)OC(C)(C)C)Cc2ccccc21.Cl>>CN1C(=O)[C@H](N)Cc2ccccc21.Cl,,C1COCCO1,,,,test
US03985727,CI.CO[C@@H]1O[C@H](COCc2ccccc2)[C@H](OCc2ccccc2)[C@H](NC(C)=O)[C@H]1OCc1ccccc1>>CO[C@@H]1O[C@H](COCc2ccccc2)[C@H](OCc2ccccc2)[C@H](N(C)C(C)=O)[C@H]1OCc1ccccc1,,CN(C)C=O,,[H-].[Na+],,test
US20100152163A1,CCCCC([Sn])=C(CCCC)CCCC.Cn1cc(Br)ccc1=O>>C=Cc1ccc(=O)n(C)c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,,,test
US06090571,COc1ccc2c(C(=O)O)c3ccccc3nc2c1.Oc1c(F)cccc1F.c1ccncc1>>COc1ccc2c(C(=O)Oc3ccccc3)c3ccccc3nc2c1,,ClCCl,O=S(Cl)Cl,,,test
US20050192347A1,CC(CO)(CCCCN)c1ccccc1.O=C=NCCCCc1ccccc1>>CC(CO)(CCCCNC(=O)NCCCCc1ccccc1)c1ccccc1,,ClCCl,,,,test
US20040043987A1,BrBr.Nc1ccc(S(N)(=O)=O)cc1S(N)(=O)=O>>Nc1c(Br)cc(S(N)(=O)=O)cc1S(N)(=O)=O,,CC(=O)O,,[K+].[OH-],,test
US20130184254A1,C1COCCN1.Clc1ncncc1I>>Ic1cncnc1N1CCOCC1,,CN(C)C=O,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110212967A1,CNC(=O)c1ccc(-c2cnc(N)nn2)cc1C.O=CC(Cl)Cc1ccc2ncccc2c1>>CNC(=O)c1ccc(-c2cnc3ncc(Cc4ccc5ncccc5c4)n3n2)cc1C,,CCO,,,,test
US20110190280A1,CC(C)(C)OC(=O)/N=N/C(=O)OC(C)(C)C.CCOCC.ClCCl.O=[N+]([O-])c1ccc(O)c(F)c1.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>O=C(OCc1ccccc1)N1CCC(Oc2ccc([N+](=O)[O-])cc2F)CC1,,CCOCC,ClCCl,,,test
US20130131035A1,CNC(=O)c1cccc(N)c1.Fc1ccc(OC2CN(c3ccnc(Cl)c3)C2)cc1>>CNC(=O)c1cccc(Nc2cc(N3CC(Oc4ccc(F)cc4)C3)ccn2)c1,,CC(C)O,,O=C(O)C(F)(F)F,,test
US20090325936A1,CON(C)C(=O)c1nc(CN2CCOCC2)c2ccccn12.Clc1cccc([Mg]I)c1Cl>>O=C(c1cccc(Cl)c1Cl)c1nc(CN2CCOCC2)c2ccccn12,,C1CCOC1,,,,test
US20110136792A1,COC(=O)c1ccc(F)c(COc2ccc(-c3ccc(F)cc3F)cc2)c1>>O=C(O)c1ccc(F)c(COc2ccc(-c3ccc(F)cc3F)cc2)c1,,C1CCOC1,,[Li+].[OH-],,test
US20060247261A1,Cc1cc(CNC(=O)c2cnc(Nc3cccc(Cl)c3)nc2C(F)(F)F)ccn1.Cl>>Cc1cc(CNC(=O)c2cnc(Nc3cccc(Cl)c3)nc2C(F)(F)F)ccn1.Cl,Cl,CCO,,,,test
US04232038,COC(=O)Cc1c(C(=O)OC)ccn1CCI>>COC(=O)c1ccn2c1C(C(=O)OC)CC2,,CN(C)C=O,,[H-].[Na+],,test
US20080287409A1,Cc1cc(OCc2sc(-c3ccc(C(F)(F)F)cc3)nc2COC2CCCCO2)ccc1-c1noc(=O)[nH]1>>Cc1cc(OCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C=O)ccc1-c1noc(=O)[nH]1,,CO,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20090018177A1,CC1(C)OCCC(c2cccc(Br)c2)O1.O=C=O>>CC1(C)OCCC(c2cccc(C(=O)O)c2)O1,,C1CCOC1,CCCCCC,[Li]CCCC,[Cl-].[NH4+],test
US20110105461A1,C1COCCN1.Cc1ccc(S(=O)(=O)OCC2COc3ccc(S(C)(=O)=O)cc3O2)cc1>>CS(=O)(=O)c1ccc2c(c1)OC(CN1CCOCC1)CO2,,CC#N,,,,test
US20130281490A1,CCO.CCOC(=O)[C@H](C(=O)CC)N(Cc1ccccc1)Cc1ccccc1>>CCOC(=O)[C@H]([C@H](O)C(C)C)N(Cc1ccccc1)Cc1ccccc1,,O,,[BH4-].[Na+],[Cl-].[NH4+],test
US20100173933A1,O=C1CCCCC1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=S(=O)(OC1=CCCCC1)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US20120252801A1,CCN1C(CC(=O)OC(C)(C)C)C(=O)OC(C)(C)C1C>>CCN1C(CC(=O)O)C(=O)OC(C)(C)C1C,,ClCCl,,O=C(O)C(F)(F)F,,test
US20130023502A1,CN1CCN(CCN2Cc3ccc(N)cc3C2)C1=O.Cl.N#CN>>CN1CCN(CCN2Cc3ccc(NC(=N)N)cc3C2)C1=O.Cl,,C1COCCO1,Cl,,,test
US20110021522A1,CC(C)(C)OC(=O)n1c(-c2cccc(N)c2)cc2ccccc21.COc1cccc2cc(C(=O)O)c(=O)oc12>>COc1cccc2cc(C(=O)Nc3cccc(-c4cc5ccccc5n4C(=O)OC(C)(C)C)c3)c(=O)oc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05773428,CC(C)C[C@H](CC(=O)NOCc1ccccc1)C(=O)N[C@H]1Cc2cn(c3ccccc23)CCCCCCNC1=O>>CC(C)C[C@H](CC(=O)NO)C(=O)N[C@H]1Cc2cn(c3ccccc23)CCCCCCNC1=O,[Pd],CCO,,C1CCOC1,,test
US20120088765A1,CCOC1CNCCO1.COc1ccc(CSc2nc(Cl)c3ncn(C)c3n2)cc1[N+](=O)[O-]>>CCOC1CN(c2nc(SCc3ccc(OC)c([N+](=O)[O-])c3)nc3c2ncn3C)CCO1,,C1CCOC1,,CCN(CC)CC,Cl,test
US20080125468A1,COC(=O)c1ccc(OC(CCC(C)(C)C)c2ccc(-c3ccc(C(F)(F)F)cc3)nc2)cc1>>CC(C)(C)CCC(Oc1ccc(C(=O)O)cc1)c1ccc(-c2ccc(C(F)(F)F)cc2)nc1,,C1CCOC1,,Cl,[Na+].[OH-],test
US20070203157A1,COc1ccc(S(=O)(=O)N(C)C(=O)C2=C(C)N(C(=O)OC(C)(C)C)c3ccnn3C2c2ccc(Cl)c(Cl)c2)cc1>>COc1ccc(S(=O)(=O)N(C)C(=O)C2=C(C)Nc3ccnn3C2c2ccc(Cl)c(Cl)c2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20070249612A1,Cc1ccccc1-c1c(C(C)(C)C)nc(Cl)c2nn(C(C)(C)C)c(=O)n12>>Cc1ccccc1-c1c(C(C)(C)C)nc(Cl)c2n[nH]c(=O)n12,,CC(Cl)Cl,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US05574042,O=C(O)c1c(Cl)cc(Cl)cc1Cl.O=[N+]([O-])O>>O=C(O)c1c(Cl)cc(Cl)c([N+](=O)[O-])c1Cl,,O=S(=O)(O)O,,,,test
US20050272794A1,C[C@@H](c1ccc(C(=O)NCCC(=O)OC(C)(C)C)cc1)n1nc(-c2cc(Cl)cc(Cl)c2)cc1OS(=O)(=O)C(F)(F)F.OB(O)c1ccc2cc(OC(F)(F)F)ccc2c1>>C[C@@H](c1ccc(C(=O)NCCC(=O)O)cc1)n1nc(-c2cc(Cl)cc(Cl)c2)cc1-c1ccc2cc(OC(F)(F)F)ccc2c1,,COCCOC,,,,test
US05866513,C=C[N+](=O)[O-].COc1ccc(C=[N+](C)[O-])c(OC)c1OC>>COc1ccc(C2C([N+](=O)[O-])CON2C)c(OC)c1OC,,Cc1ccccc1,,,,test
US20150073011A1,C=CCONS(=O)(=O)c1ccccc1[N+](=O)[O-].CC1=C[C@H](O)CN(C(=O)OC(C)(C)C)[C@@H]1CO[Si](C)(C)C(C)(C)C>>C=CCON([C@@H]1C=C(C)[C@@H](CO[Si](C)(C)C(C)(C)C)N(C(=O)OC(C)(C)C)C1)S(=O)(=O)c1ccccc1[N+](=O)[O-],,Cc1ccccc1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20060030609A1,CN.COC(=O)[C@H]1CN(c2ccc3c(c2)CC(=O)N3C)C(=O)O1>>CNC(=O)C1CN(c2ccc3c(c2)CC(=O)N3C)C(=O)O1,,CO,,,,test
US20020061996A1,CCCOc1cc(/C=C/C(=O)O)ccc1OCC.CCOC(C)=O.Cc1ccccc1>>CCCOc1cc(/C=C/C(=O)OCCCCCCCCO)ccc1OCC,,CCOC(C)=O,Cc1ccccc1,,,test
US05478832,CCCCc1nc(Cl)c(C=O)n1Cc1ccc2nc(-c3ccccc3C(=O)OC)ccc2c1>>CCCCc1nc(Cl)c(C=O)n1Cc1ccc2nc(-c3ccccc3C(=O)O)ccc2c1,,CCO,,O,[Na+].[OH-],test
US20100048636A1,CC(C)(C)OC(=O)N[C@H](CN=[N+]=[N-])C[C@@H]1CCCCOC1>>CC(C)(C)OC(=O)N[C@H](CN)C[C@@H]1CCCCOC1,[Pd],CO,,,,test
US20100093694A1,CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3ccc(-c4ccccc4Cl)c(C(=O)O)c3)cc12.NC1(c2ccccn2)CC1>>CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3ccc(-c4ccccc4Cl)c(C(=O)NC4(c5ccccn5)CC4)c3)cc12,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US06881733B1,CC(C)(C)OOC(=O)OC(=O)OOC(C)(C)C.CC1CC(=O)CCN1>>CC1CC(=O)CCN1C(=O)OC(C)(C)C,,ClC(Cl)Cl,O,O=C([O-])O.[Na+],,test
US20110144105A1,COC(=O)c1ccc(C(=CC2CCCC2)c2cc3cc(F)cnc3n2S(=O)(=O)c2ccccc2)cc1F>>COC(=O)c1ccc(C(=CC2CCCC2)c2cc3cc(F)cnc3[nH]2)cc1F,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20100256188A1,CCOC(=O)c1cc([N+](=O)[O-])c(NC)cc1OCC(F)F>>CCOC(=O)c1cc(N)c(NC)cc1OCC(F)F,[Ni],C1CCOC1,,O=S(=O)([O-])[O-].[Na+].[Na+],,test
US20110112052A1,CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12>>CC(C)(C)C[C@@H]1N[C@@H](C(=O)NC2CCC(O)CC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12,,CO,O,,,test
US20090124612A1,CC(C)(C)OC(=O)Cc1ccc2nc[nH]c(=O)c2c1>>O=C(O)Cc1ccc2nc[nH]c(=O)c2c1,,CCOC(C)=O,,Cl,,test
US20040097731A1,CCOC(=O)N1CCN(c2ccc(C=O)c(Cl)c2)CC1.Fc1ccc(Nc2ccc(Br)cn2)c(F)c1>>CCOC(=O)N1CCN(c2ccc(C(O)c3ccc(Nc4ccc(F)cc4F)nc3)c(Cl)c2)CC1,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US20110312936A1,CCN.O=C1CCC2(CC1)OCCO2>>CCNC1CCC2(CC1)OCCO2,,CC#N,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20120040954A1,O=S(=O)(OCC(F)(F)F)C(F)(F)F.O=c1[nH]c(-c2ccc(N3CCNCC3)cc2)nc2ccccc12>>O=c1[nH]c(-c2ccc(N3CCN(CC(F)(F)F)CC3)cc2)nc2ccccc12,,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US04698345,CC(=O)OC(C)=O.CCCc1c2nc(C(=O)OCC)cc(NC)c2cc2c(=O)cc(C(=O)OCC)oc12>>CCCc1c2nc(C(=O)OCC)cc(N(C)C(C)=O)c2cc2c(=O)cc(C(=O)OCC)oc12,,CC(=O)OC(C)=O,,CC(=O)O,O,test
US20110245240A1,CCOC(=O)C1(c2cccnc2[N+](=O)[O-])Oc2ccc(Br)cc2C1=O>>O=C1Nc2ncccc2C12Oc1ccc(Br)cc1C2=O,[Fe],CC(=O)O,,,,test
US20060252751A1,C1CNC1.Fc1ccc(Br)cn1>>Brc1ccc(N2CCC2)nc1,,CS(C)=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US04704459,CCOC(=O)c1cn(-c2ccc(F)cc2F)c2nc(Cl)c(F)cc2c1=O>>O=C(O)c1cn(-c2ccc(F)cc2F)c2nc(Cl)c(F)cc2c1=O,,Cl,O,,,test
US04239887,CI.Cc1ccc2c(n1)sc1c(O)nnnc12>>Cc1ccc2c(n1)sc1c(=O)n(C)nnc12,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20060041146A1,CC(C)(C)OC(=O)NC(C(=O)OCc1ccccc1)c1ccc(OS(=O)(=O)C(F)(F)F)cc1.CCOP([O-])OCC>>CCOP(=O)(OCC)c1ccc(C(NC(=O)OC(C)(C)C)C(=O)OCc2ccccc2)cc1,,CC#N,CCOC(C)=O,CN1CCOCC1,,test
US20120214803A1,Nc1ccccc1.O=[N+]([O-])c1c(Cl)ccc2cccnc12>>O=[N+]([O-])c1c(Nc2ccccc2)ccc2cccnc12,,CCOC(C)=O,c1ccncc1,,,test
US05189054,CCOC(=O)c1[nH]c2cc(F)ccc2c1N.ClCCl.O=C(Cl)c1ccccc1>>CCOC(=O)c1[nH]c2cc(F)ccc2c1NCC(=O)c1ccccc1,,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US20100113410A1,CC1(C)OCC(CC(=O)c2c(Cl)nc(N)nc2Cl)O1.COc1c(C)cnc(CNN)c1C>>COc1c(C)cnc(Cn2nc(CC3COC(C)(C)O3)c3c(Cl)nc(N)nc32)c1C,,ClCCl,,CCN(CC)CC,Cl,test
US20100075965A1,CC(=O)Nc1nc2ccc(-c3cnc(N)c(C(F)(F)F)c3)cn2c1C#Cc1ccccc1.O=C(O)C(F)(F)F>>CC(=O)Nc1nc2ccc(-c3cnc(N)c(C(F)(F)F)c3)cn2c1CCc1ccccc1.O=C(O)C(F)(F)F,[Pd],CO,,[H][H],,test
US20130029383A1,O=C(CO)[C@@H](O)[C@H](O)[C@H](O)CO.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>O=C(CO)[C@@H](O)[C@H](O)[C@H](O)CO.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO,,CC(=O)CC(C)C,,[Cl-].[Na+],,test
US05045556,CCOC(=O)C(Cl)=NC.NNC(=O)Cc1ccccc1Cl>>CCOC(=O)c1nnc(Cc2ccccc2Cl)n1C,,ClCCl,,Cl,,test
US20060264444A1,CCSc1ccc(Oc2c(C)[nH]c3ccc(C(F)(F)F)cc23)cc1.O=S([O-])OO>>CCS(=O)(=O)c1ccc(Oc2c(C)[nH]c3ccc(C(F)(F)F)cc23)cc1,,CC#N,,O,,test
US20150148332A1,CC(C)=CC(=O)NC(=S)N1CCCC1.CI>>CS/C(=N\C(=O)C=C(C)C)N1CCCC1,,C1CCOC1,,O=C([O-])[O-].[Na+].[Na+],,test
US20050153959A1,C1CCNCC1.Cc1cc(CC(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)c2ccc(C=O)cn2)cc2cn[nH]c12>>Cc1cc(CC(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)c2ccc(CN3CCCCC3)cn2)cc2cn[nH]c12,C1CCNCC1,CC(Cl)Cl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20060148858A1,Brc1ccc(Br)nc1.CCOC(=O)CCc1c[nH]nc1C(CC)CC>>CCOC(=O)CCc1cn(-c2ccc(Br)cn2)nc1C(CC)CC,,CN(C)C=O,,Cl,[H-].[Na+],test
US20070142448A1,CC(=O)Nc1c(OCc2ccccc2)cc(C#N)cc1[N+](=O)[O-]>>Cc1nc2c(OCc3ccccc3)cc(C#N)cc2[nH]1,[Fe],CC(=O)O,,,,test
US20040138065A1,FC(F)(F)c1ccc(CBr)c(Cl)c1.N#CC(C#N)CCC(F)(F)F>>N#CC(C#N)(CCC(F)(F)F)Cc1ccc(C(F)(F)F)cc1Cl,,CN(C)C=O,,[H-].[Na+],,test
US20110311459A1,CCOC(=O)C(Br)c1ccccc1.CNc1ccccc1>>CCOC(=O)C(c1ccccc1)N(C)c1ccccc1,,CC#N,,,,test
US20070197512A1,CCC1Oc2c(C)cc(C)cc2N(CCC(=O)OC)C1=O>>CCC1Oc2c(C)cc(C)cc2N(CCC(=O)O)C1=O,,CO,,[Na+].[OH-],,test
US20040063705A1,CN1CCN(c2ccc(N)cc2)CC1.Cc1cccc(C)c1N(c1ccnc(Cl)n1)c1nc2ccccc2[nH]1>>Cc1cccc(C)c1N(c1ccnc(Nc2ccc(N3CCN(C)CC3)cc2)n1)c1nc2ccccc2[nH]1,,CC(=O)O,,[Na+].[OH-],,test
US04032524,CCN(CC)C(=O)Cl.O=c1[nH]cc(F)c(=O)[nH]1>>CCN(CC)C(=O)n1cc(F)c(=O)[nH]c1=O,,CC(=O)N(C)C,,[H-].[Na+],,test
US05155236,CC=C(OCC)OCC.CCOC=C(C(C)=O)C(=O)NC(=O)OCC.Cc1ccccc1>>CCCCCC.CCOC(=O)NC(=O)C1=C(C)OC(OCC)(OCC)[C@@H](C)[C@@H]1OCC,,Cc1ccccc1,,,,test
US20150344429A1,CCN(CC)S(F)(F)F.OC1(c2cnccc2OCC(F)(F)F)CCC1>>FC(F)(F)COc1ccncc1C1(F)CCC1,,ClCCl,,,,test
US05001125,CSc1ccc(Cl)nn1.Cc1cccc(C2=CCNCC2)c1>>CSc1ccc(N2CC=C(c3cccc(C)c3)CC2)nn1,,CCCCO,,Cl,O=C([O-])[O-].[Na+].[Na+],test
US20130211075A1,Fc1ccc(Br)cn1.N#CC1CCC2(CC1)OCCO2>>N#CC1(c2ccc(Br)cn2)CCC2(CC1)OCCO2,,C1CCOC1,,O,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],test
US20040116466A1,Nc1ccc(-c2nc3cc(NC(=O)C4CCCCC4)ncc3[nH]2)cc1.O=C(Cl)C1CCCCC1>>O=C(Nc1cc2nc(-c3ccc(C(=O)C4CCCCC4)cc3)[nH]c2cn1)C1CCCCC1,,C1CCOC1,c1ccncc1,,,test
US20020045749A1,O=C(Cl)C(=O)Cl.O=C(O)c1cc2ccccc2s1>>O=C(Cl)c1cc2ccccc2s1,,ClCCl,,CN(C)C=O,,test
US20120184531A1,Cc1ccc(S(=O)(=O)Cl)cc1.OCCc1cc2cc(Br)cc(Cl)c2o1>>Cc1ccc(S(=O)(=O)OCCc2cc3cc(Br)cc(Cl)c3o2)cc1,,ClCCl,,CCN(CC)CC,,test
US05578620,[N-]=[N+]=NCC(O)COc1cccc(Cl)c1>>NCC(O)COc1cccc(Cl)c1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20090005376A1,CCCC(=O)Nc1cnc2ccccc2c1Cl.NOCc1ccccc1>>CCCc1nc2cnc3ccccc3c2n1OCc1ccccc1,,CCO,,Cl,,test
US06207678B1,O=C(OCC[C@H](Cn1ccnc1C(=O)c1cccc2c1CCCC2)c1ccc(Cl)c(Cl)c1)c1cccc2c1CCCC2>>O=C(c1cccc2c1CCCC2)c1nccn1C[C@@H](CCO)c1ccc(Cl)c(Cl)c1,,CO,,[Na+].[OH-],,test
US20120157430A1,CC1(C)OB(c2cncc(F)c2)OC1(C)C.CCC(NC(=O)OC(C)(C)C)c1cc(Cl)c(C)c(Br)c1OC>>CCC(NC(=O)OC(C)(C)C)c1cc(Cl)c(C)c(-c2cncc(F)c2)c1OC,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,O,O=C([O-])[O-].[K+].[K+],,test
US04279918,COC(=O)C(=C1CCCN1C)c1ccc(OC)c(OC)c1>>COc1ccc(C=C2CCCN2C)cc1OC,,Cl,,[Na+].[OH-],,test
US20050267148A1,Cn1c(C=O)cc2ccccc21.Nc1ccccc1[N+](=O)[O-]>>Cn1cc(CNc2ccccc2[N+](=O)[O-])c2ccccc21,,C1CCOC1,CC(=O)O,O=C([O-])O.[Na+],,test
US20080153817A1,CC(C)O.Cc1ccc(S(=O)(=O)O)cc1.NN>>c1ccc2[nH]ccc2c1,,O,,,,test
US20090298823A1,CC(=O)N1CCN(c2ccc(N)cc2)CC1.CC(C)(C)OC(=O)NCC1CCN(c2nc(Cl)nc3[nH]cnc23)CC1>>CC(=O)N1CCN(c2ccc(Nc3nc(N4CCC(CN)CC4)c4nc[nH]c4n3)cc2)CC1,,CCCCO,,C[Si](C)(C)Cl,,test
US20080058327A1,C[C@@H]1CCc2ncnc(N3CCN(C(=O)C4(c5ccc(Cl)cc5)CCN(C(=O)OC(C)(C)C)C4)CC3)c21.Cl.ClCCl>>C[C@@H]1CCc2ncnc(N3CCN(C(=O)C4(c5ccc(Cl)cc5)CCNC4)CC3)c21.Cl.Cl,,C1COCCO1,ClCCl,,,test
US20040067985A1,CCNCC.Cc1ccc(C(=O)O)cn1>>CCN(CC)C(=O)c1ccc(C)nc1,,ClCCl,,CCN(CC)CC,O=S(Cl)Cl,test
US20160115146A1,CC=O.CCOC(=O)c1cc2ccc(NCc3ccccc3)cc2oc1=O>>CCOC(=O)c1cc2ccc(N(CC)Cc3ccccc3)cc2oc1=O,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20060194969A1,Cc1nc2c(OCc3ccccc3)cc(C(=O)N(C)C)cc2n1C>>Cc1nc2c(O)cc(C(=O)N(C)C)cc2n1C,[Pd],CO,,,,test
US20150175599A1,CCN(CC)CC.CN(C)C=O.Cc1cc2cc(C#N)ccc2n1Cc1ccc(Cl)cc1>>COc1cc(N)ccn1,CN(C)C=O,ClCCl,,O=C(Cl)C(=O)Cl,,test
US20150057264A1,CCOC(=O)c1cc(F)c[nH]1.O=C(CBr)c1ccc(C2CCN(C(=O)C(F)(F)F)CC2)cc1>>CCOC(=O)c1cc(F)cn1CC(=O)c1ccc(C2CCN(C(=O)C(F)(F)F)CC2)cc1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20150119435A1,[N-]=[N+]=NCCOCCOCCOCCOCCOCCOC12CC3CC(CC(C3)C1)C2>>NCCOCCOCCOCCOCCOCCOC12CC3CC(CC(C3)C1)C2,,C1CCOC1,CCOC(C)=O,O,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20130123486A1,CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCNC(CC(C)C)=C1C(=O)CC(C)(C)CC1=O)C(=O)O>>CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O,,CN(C)C=O,,NN,O,test
US05334740,COCOC1CC2=NOCC2C2OC(C)(C)OC12.OB(O)O>>COCOC1CC(=O)C(CO)C2OC(C)(C)OC12,[Ni],CCOCC,CO,O,[H][H],test
US20150112067A1,C[C@@H]1[C@H](c2c(F)ccc(F)c2F)C[C@H](NC(=O)c2cnc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C(=O)N1CC(F)(F)F.O=C(O)[C@H](O)[C@@H](O)C(=O)O>>C[C@@H]1[C@H](c2c(F)ccc(F)c2F)C[C@H](NC(=O)c2cnc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C(=O)N1CC(F)(F)F.O=C(O)[C@H](O)[C@@H](O)C(=O)O,,CC(=O)CC(C)C,,O,,test
US20100009957A1,CC#N.O=C1CCCCN(C(=O)OCc2ccccc2)CCC1.O=C1[C@H]2NCC[C@H]2N1S(=O)(=O)O>>O=C(OCc1ccccc1)N1CCCCC(NC(=O)N2CC[C@@H]3[C@H]2C(=O)N3S(=O)(=O)O)CCC1,,O,,O=C([O-])O.[Na+],,test
US20040127536A1,COC(=O)c1ccc(C(=O)Nc2ccc3c(c2)c(-c2ccc(OC)cc2)nn3C2CCCCO2)cc1>>COC(=O)c1ccc(C(=O)Nc2ccc3[nH]nc(-c4ccc(OC)cc4)c3c2)cc1,,C1CCOC1,Cl,O=C([O-])O.[Na+],,test
US20100204196A1,CNC(=O)c1c(F)cccc1Nc1nc(Nc2cc3c(cc2OC)CCN3C(=O)CN(C)C)nc2c1ccn2S(=O)(=O)c1ccc(C)cc1>>CNC(=O)c1c(F)cccc1Nc1nc(Nc2cc3c(cc2OC)CCN3C(=O)CN(C)C)[nH]c2nccc1-2,,C1COCCO1,CCOC(C)=O,[K+].[OH-],,test
US20050267095A1,CNCC1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1.CS(=O)(=O)Cl>>CN(CC1(c2ccc(OCCCN3CCCC3)cc2)CCOCC1)S(C)(=O)=O,,ClCCl,,CCN(CC)CC,,test
US04892885,BrCc1ccccc1.CCNCC>>CCN(CC)Cc1ccccc1,,CCOCC,,,,test
US05107010,C=CC(C)(C=CC1=C(C)C(=O)C(O)CC1(C)C)O[Si](C)(C)C.O=S(O)c1ccccc1>>CC(C=CC1=C(C)C(=O)C(O)CC1(C)C)=CCS(=O)(=O)c1ccccc1,,CC(=O)O,,[Na],,test
US20070185153A1,CC(=O)OCc1cc(OCc2ccccc2)c(SC(C)(C)C)cn1>>CC(=O)OCc1cc(=O)c(SC(C)(C)C)c[nH]1,[Pd],C1COCCO1,O,,,test
US20150018363A1,CNc1cc(Br)ccc1N.O=C1CC(C(=O)O)C1>>Nc1cc(Br)ccc1NC(=O)C1CC(=O)C1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030055097A1,COCCCBr.NC(=O)c1n[nH]c2ccccc12>>COCCCc1cccc2[nH]nc(C(N)=O)c12,,CN(C)C=O,,O,[H-].[Na+],test
US20100227859A1,COC(=O)[C@@H](NS(=O)(=O)c1ccc2c(c1)oc1cc(I)ccc12)C(C)C.Cc1ccc(B2OC(C)(C)C(C)(C)O2)o1>>COC(=O)[C@@H](NS(=O)(=O)c1ccc2c(c1)oc1cc(-c3ccc(C)o3)ccc12)C(C)C,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[K+].[K+],,test
US20080027117A1,BrCc1ccccc1.O=[N+]([O-])c1ccc(O)cc1>>O=[N+]([O-])c1ccc(OCc2ccccc2)cc1,,CCCCCC,CCOC(C)=O,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20060281648A1,CC1=CCC(C2=CCC3(CC2)CO3)C1(C)C>>CC1=CCC(C2=CCC(C=O)CC2)C1(C)C,,Cc1ccccc1,,CCOCC,FB(F)F,test
US05491172,COC(=O)CC=Cc1c(C(C)C)cc(C(C)C)cc1C(C)C>>CC(C)c1cc(C(C)C)c(C=CCC(=O)O)c(C(C)C)c1,,CO,O,[Na+].[OH-],,test
US20020156081A1,CN1CCN([C@@H]2CC[C@H](n3nc(-c4ccc(Oc5ccc(C#N)cc5)cc4)c4c(N)ncnc43)CC2)CC1.OO>>CN1CCN([C@@H]2CC[C@H](n3nc(-c4ccc(Oc5ccc(C(N)=O)cc5)cc4)c4c(N)ncnc43)CC2)CC1,O,C1COCCO1,O,O=C(O)CC(O)(CC(=O)O)C(=O)O,[Na+].[OH-],test
US20140206687A1,O=[N+]([O-])c1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1F.OCCCN1CCOCC1>>O=[N+]([O-])c1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCOCC1,,CS(C)=O,O,Cl,CC(C)(C)[O-].[K+],test
US20100069381A1,CCOC(=O)CCC(=O)Cl.c1cc2c(cc1-c1nnn[nH]1)CCO2>>CCOC(=O)CCc1nnc(-c2ccc3c(c2)CCO3)o1,,CCOC(C)=O,c1ccncc1,,,test
US20050258396A1,CCCCCCCCOc1ccc(C(=O)Cl)cc1.OC1CCC(c2ccc(OCCCCCCCCCCCBr)cc2)CC1>>CCCCCCCCOc1ccc(C(=O)OC2CCC(c3ccc(OCCCCCCCCCCCBr)cc3)CC2)cc1,CN(C)c1ccncc1,ClCCl,,,,test
US20060030595A1,O=C(c1cccnc1)c1ccncn1.c1cncc(Cc2cccnc2)c1>>OC(c1cccnc1)(c1ccncn1)C(c1cccnc1)c1cccnc1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20140275153A1,CC(C)(C)OC(=O)N1CC=C(c2cc3c(-c4ccc5nnn(CC6CCOCC6)c5c4)ccnc3[nH]2)CC1>>C1=C(c2cc3c(-c4ccc5nnn(CC6CCOCC6)c5c4)ccnc3[nH]2)CCNC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04766125,Fc1ccc(C2(CCCOC3CCCCO3)OCc3ccccc32)cc1>>OCCCC1(c2ccc(F)cc2)OCc2ccccc21,,CCO,Cl,,,test
US20050164235A1,BrC(Br)(Br)Br.CC(C)(C)[Si](OCCOCCOCCOCCO)(c1ccccc1)c1ccccc1>>CC(C)(C)[Si](OCCOCCOCCOCCBr)(c1ccccc1)c1ccccc1,,C1CCOC1,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090196912A1,COc1cccc(C=O)c1.Nc1cncc(Br)c1>>COc1cccc(CNc2cncc(Br)c2)c1,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20130005995A1,CC[C@H](C)CC(F)(F)C(=O)CP(=O)(OC)OC.COC(=O)CCCCCC[C@H]1[C@@H](OC(C)=O)C[C@@H](OC2CCCCO2)[C@@H]1C=O>>CC[C@H](C)CC(F)(F)C(=O)/C=C/[C@H]1[C@H](OC2CCCCO2)C[C@H](OC(C)=O)[C@@H]1CCCCCCC(=O)OC,,COC(C)(C)C,O,[Li+].[OH-],,test
US05541229,CCCCc1nc2ccc(NC(=O)OC3CCCCC3)cc2n1Cc1ccc(-c2ccccc2C(=O)OC(C)(C)C)cc1>>CCCCc1nc2ccc(NC(=O)OC3CCCCC3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20080114006A1,CCOC(=O)c1cc(C(C)(C)C)nn1CC(=O)N(C)C>>CCOC(=O)c1cc(C(C)(C)C)nn1CCN(C)C,,C1CCOC1,,B,,test
US04288437,N.O=C(c1ccccc1)c1sc2ccccc2c1O>>N/C(=C1/Sc2ccccc2C1=O)c1ccccc1,,O,,,,test
US20050250797A1,COc1cc2c(Cl)ncnc2cc1OCCCN1CCOCC1.Nc1c(Cl)cc(C#CCOCC2CC2)c2c1OCO2>>COc1cc2c(Nc3c(Cl)cc(C#CCOCC4CC4)c4c3OCO4)ncnc2cc1OCCCN1CCOCC1,,CN(C)C=O,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20070197604A1,CC(=O)c1cccc(-c2ccc(-c3nc(CCO)c(C)o3)cc2)c1.CS(=O)(=O)Cl>>CC(=O)c1cccc(-c2ccc(-c3nc(CCOS(C)(=O)=O)c(C)o3)cc2)c1,,ClCCl,,CCN(CC)CC,,test
US20130190290A1,COc1ccc(Cn2cc(-c3cc4n(-c5cc(NC(=O)c6cc(N7CCN(C)CC7)cc(C(C)(C)C)c6)ccc5C)ccn4n3)cn2)cc1>>Cc1ccc(NC(=O)c2cc(N3CCN(C)CC3)cc(C(C)(C)C)c2)cc1-n1ccn2nc(-c3cn[nH]c3)cc12,,O=C(O)C(F)(F)F,,,,test
US20160166575A1,C#Cc1cccc(N)c1.CC(=O)Cl>>C#Cc1cccc(NC(C)=O)c1,,ClCCl,,CC(C)OC(C)C,,test
US05134231,C=C(C)C.COC(=O)[C@@H](C)CO>>COC(=O)[C@@H](C)COC(C)(C)C,,ClCCl,,O=S(=O)(O)O,,test
US20080039459A1,C=O.CS(=O)(=O)N(Cc1cc2nc(Cl)nc(N3CCOCC3)c2s1)C1CCNC1>>CN1CCC(N(Cc2cc3nc(Cl)nc(N4CCOCC4)c3s2)S(C)(=O)=O)C1,,[Na+],[OH-],O=CO,,test
US20050153971A1,CCCC(=O)OC[C@H]1CO1.O=C(Nc1cccc(F)c1)OCc1ccccc1>>O=C1OC(CO)CN1c1cccc(F)c1,,C1CCOC1,,[Li]CCCC,,test
US20110172245A1,CC(=O)OCC(=O)Cl.Nc1nc2ccc(Oc3cccc(C(=O)Nc4cccc(C(F)(F)F)c4)c3)cc2s1>>O=C(CO)Nc1nc2ccc(Oc3cccc(C(=O)Nc4cccc(C(F)(F)F)c4)c3)cc2s1,,CN(C)C=O,,O,,test
US20120065173A1,C[C@H](N)[C@H](Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1.Cc1noc(C)c1S(=O)(=O)Cl>>Cc1noc(C)c1S(=O)(=O)N[C@@H](C)[C@H](Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,O,test
US20050070599A1,O=C(NOCc1ccccc1)C1(NS(=O)(=O)c2ccc(Oc3ccc(F)cc3)cc2)CCOCC1>>O=C(NO)C1(NS(=O)(=O)c2ccc(Oc3ccc(F)cc3)cc2)CCOCC1,[Pd],CCOC(C)=O,,,,test
US20140005189A1,CC(C)(C)OC(=O)Nc1nc2ccc(S)cc2s1.Clc1nnc2ccc(N3CCOCC3)nn12>>CC(C)(C)OC(=O)Nc1nc2ccc(Sc3nnc4ccc(N5CCOCC5)nn34)cc2s1,,CCO,,[BH4-].[Na+],,test
US20030065170A1,Nc1ccc(Cl)c(S(N)(=O)=O)c1O.O=C=NCc1ccccc1>>NS(=O)(=O)c1c(Cl)ccc(NC(=O)NCc2ccccc2)c1O,,CCOC(C)=O,CN(C)C=O,,,test
US04230628,CCOC(=O)[C@H](C)N.COC(=O)CCCCCCCCCCCCCCCN(C(=O)C(F)(F)F)c1ccc(C(=O)Cl)cc1>>COC(=O)CCCCCCCCCCCCCCCNc1ccc(C(=O)N[C@@H](C)C(=O)O)cc1,,CCOCC,,CCN(CC)CC,,test
US04758585,CCOC(=O)CN1C(=O)C[C@@H]2CCCCCC[C@@H]21.N>>NC(=O)CN1C(=O)C[C@@H]2CCCCCC[C@@H]21,,CO,,CCOCC,,test
US20030228469A1,Br.OCCCCCCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F>>FC(F)(F)C(F)(F)C(F)(F)C(F)(F)CCCCCCCCBr,,O,,O=S(=O)(O)O,,test
US20120308524A1,OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O>>O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO,,O=P([O-])([O-])[O-],,,,test
US04492693,COC(C(=O)O)c1csc2cc(F)ccc12.O=C(Cl)C(=O)Cl>>COC(C(=O)Cl)c1csc2cc(F)ccc12,CN(C)C=O,c1ccccc1,,,,test
US04126689,CCI.Cc1cccc(C)c1N(C(=O)Cc1ccccc1)C1CCNCC1>>CCN1CCC(N(C(=O)Cc2ccccc2)c2c(C)cccc2C)CC1,,c1ccccc1,,[I-].[K+],O=C([O-])[O-].[Na+].[Na+],test
US20090325985A1,COc1cnc(-n2cnc(C)n2)c2[nH]cc(C(=O)C(=O)O)c12.O=C(O)C(F)(F)F.c1ccc(-c2nccc3c2CCNC3)cc1>>COc1cnc(-n2cnc(C)n2)c2[nH]cc(C(=O)C(=O)N3CCc4c(ccnc4-c4ccccc4)C3)c12.O=C(O)C(F)(F)F,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20160152599A1,COc1ccc2c(C(=O)N(c3ccccc3)c3ccccc3)nn(-c3ccccc3C(=O)N3Cc4ccccc4C[C@H]3CNC(=O)OC(C)(C)C)c2c1>>COc1ccc2c(C(=O)N(c3ccccc3)c3ccccc3)nn(-c3ccccc3C(=O)N3Cc4ccccc4C[C@H]3CN)c2c1,,C1COCCO1,Cl,[Na+].[OH-],,test
US20060019961A1,CCI.CC[C@@H]1C(=O)Nc2ccc(F)cc2N1C(=O)c1ccc(OC)cc1OC>>CC[C@@H]1C(=O)N(CC)c2ccc(F)cc2N1C(=O)c1ccc(OC)cc1OC,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20120010189A1,CC(C)(C)OC(=O)N1CC(OS(C)(=O)=O)C1.Cc1cc(CN2CCOCC2)ccc1O>>Cc1cc(CN2CCOCC2)ccc1OC1CN(C(=O)OC(C)(C)C)C1,,CN(C)C=O,,O,[H-].[Na+],test
US20090221600A1,CC(=O)N1CC[C@H](n2c(=O)c(-c3ccccc3C)cc3cnc(S(C)(=O)=O)nc32)C1.CC(C)(C)OC(=O)N1CCC(N)CC1>>CC(=O)N1CC[C@H](n2c(=O)c(-c3ccccc3C)cc3cnc(NC4CCN(C(=O)OC(C)(C)C)CC4)nc32)C1,,O,,c1ccncc1,,test
US20080167307A1,CC(C)(C)OC(=O)C(C)(C)Sc1nc(CC(=O)Nc2ccc(-c3ccc(Cl)cc3)cn2)cs1.ClCCl>>CC(C)(Sc1nc(CCNc2ccc(-c3ccc(Cl)cc3)cn2)cs1)C(=O)O.Cl,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160168100A1,COc1cc(C=O)cc(OC)c1OCc1ccccc1.O=C(O)CC(=O)O>>COc1cc(/C=C/C(=O)O)cc(OC)c1OCc1ccccc1,,O,c1ccncc1,C1CCNCC1,Cl,test
US20050159465A1,COc1ccc(Br)c(C)c1.COc1ccc(C=O)c(F)c1>>COc1ccc(C(O)c2ccc(OC)cc2F)c(C)c1,,C1CCOC1,,[Li]CCCC,,test
US05739345,Cn1c(COc2ccc(CC3SC(=O)N(C(c4ccccc4)(c4ccccc4)c4ccccc4)C3=O)cc2)nc2cccnc21>>Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2cccnc21,[Pd],CO,,,,test
US20030027743A1,CC[C@H](NC(=O)OCc1ccccc1)C(=O)N1c2ccccc2C[C@H]1C(=O)NC>>CC[C@H](N)C(=O)N1c2ccccc2C[C@H]1C(=O)NC,[Pd],CO,,O=C(O)C(=O)O,,test
US05556864,CC(C)c1ccc(CCCCc2ccccc2OCC(O)CN(C)C)cc1.Cl>>CC(C)c1ccc(CCCCc2ccccc2OCC(O)CN(C)C)cc1.Cl,,C1COCCO1,CCOC(C)=O,,,test
US20100063104A1,C[C@@]1(C(=O)O)COC(=O)O1.O=C(Cl)C(=O)Cl>>C[C@@]1(C(=O)Cl)COC(=O)O1,,ClCCl,,CN(C)C=O,,test
US20160272633A1,C1CNC1.O=S(=O)(Cl)c1ccc(Br)cc1>>O=S(=O)(c1ccc(Br)cc1)N1CCC1,,ClCCl,,,,test
US06323235B1,COC(=O)COc1cccc2c(CCOC3CCCCO3)c(C=CCOC(C)=O)oc12>>COC(=O)COc1cccc2c(CCO)c(CCCOC(C)=O)oc12,[Pd],CO,,CCCCCC,CCOC(C)=O,test
US20060252750A1,COC(=O)[C@@H](Cc1cc(C)c(Cl)c(C)c1)OC(=O)N1CCC(N2CCc3ccccc3NC2=O)CC1>>Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)O)cc(C)c1Cl,,C1CCOC1,O,[Li+].[OH-],,test
US20150038438A1,CC1CCc2cc(Cl)ccc2C(=O)C1.COc1ccc(CN)c(OC)c1>>COc1ccc(CN=C2CC(C)CCc3cc(Cl)ccc32)c(OC)c1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,CCN(CC)CC,,test
US20060019965A1,BrP(Br)Br.CC(O)c1ccc2nccnc2c1>>CC(Br)c1ccc2nccnc2c1,,CCOCC,,,,test
US20080300270A1,CCCC1CC(=O)C2=C(C1)NC(C)=C(C#N)C2c1cc(Br)c(OCc2cccc(N)c2)c(NS(C)(=O)=O)c1.CS(=O)(=O)Cl>>CCCC1CC(=O)C2=C(C1)NC(C)=C(C#N)C2c1cc(Br)c(OCc2cccc(NS(C)(=O)=O)c2)c(NS(C)(=O)=O)c1,,CCOC(C)=O,ClCCl,c1ccncc1,,test
US20140275027A1,COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCC4(CC3)OCCO4)cc12>>COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCC(=O)CC3)cc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150018376A1,Cn1nc(NC(=O)n2ccc3cc(Oc4cc(COS(C)(=O)=O)ncn4)ccc32)cc1C(F)(F)F.N>>Cn1nc(NC(=O)n2ccc3cc(Oc4cc(CN)ncn4)ccc32)cc1C(F)(F)F,,C1CCOC1,,,,test
US20040122244A1,COC1=C(OC)C(=O)C(Cc2cccc(C(=O)O)c2OC(C)=O)=C(C)C1=O.Nc1ccc(N2CCOCC2)cc1>>COC1=C(OC)C(=O)C(Cc2cccc(C(=O)Nc3ccc(N4CCOCC4)cc3)c2OC(C)=O)=C(C)C1=O,,ClCCl,,CCN(CC)CC,CN1CC[NH+](C)C1Cl.[Cl-],test
US06383490B1,COC(=O)[C@H]1[C@@H](OC(=O)c2ccccc2)C[C@@H]2CC[C@H]1N2C>>CN1[C@H]2CC[C@@H]1[C@@H](C(=O)O)[C@@H](O)C2,,Cl,,,,test
US06326386B1,CC(C)N(CCCNC(=O)C(C)(C)C)C(=O)c1cc(Cl)cc(OCCN(C(=O)OC(C)(C)C)c2ccncc2)c1.O=C(O)C(F)(F)F>>CC(C)N(CCCNC(=O)C(C)(C)C)C(=O)c1cc(Cl)cc(OCCNc2ccncc2)c1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20100234354A1,CN1CCNCC1.O=Cc1cnc(-c2cccc(Cn3nc(-c4cc(F)cc(F)c4)ccc3=O)c2)nc1>>CN1CCN(Cc2cnc(-c3cccc(Cn4nc(-c5cc(F)cc(F)c5)ccc4=O)c3)nc2)CC1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20030220377A1,COc1ccc(-c2c(-c3ccccc3)[nH]c3ccccc23)cc1>>Oc1ccc(-c2c(-c3ccccc3)[nH]c3ccccc23)cc1,,ClCCl,O,BrB(Br)Br,CO,test
US04670447,CN1CCC(c2n[nH]c3ccccc23)CC1.O=C(Cl)c1cccc(Cl)c1>>CN1CCC(c2nn(C(=O)c3cccc(Cl)c3)c3ccccc23)CC1.Cl,,CCOCC,,,,test
US20070232627A1,O=C(Nc1cccc(Br)c1)c1ccc(Cl)c([N+](=O)[O-])c1.Oc1cccc(S)c1>>O=C(Nc1cccc(Br)c1)c1ccc(Sc2cccc(O)c2)c([N+](=O)[O-])c1,,CN(C)C=O,,Cl,O=C([O-])[O-].[Cs+].[Cs+],test
US20060205676A1,COc1ccc(COc2cccc(OCC3CC3)c2-c2cc(C3CCCN(C(=O)OC(C)(C)C)C3)c(CSc3ccccc3)c(N)n2)cc1.Cl>>Cl.Nc1nc(-c2c(O)cccc2OCC2CC2)cc(C2CCCNC2)c1CSc1ccccc1,,C1COCCO1,CCOC(C)=O,,,test
US20070185155A1,CCN(CC)c1cccc(OCCCBr)c1.OC(c1ccccc1)(c1ccccc1)C12CCN(CC1)CC2>>CCN(CC)c1cccc(OCCC[N+]23CCC(C(O)(c4ccccc4)c4ccccc4)(CC2)CC3)c1.[Br-],,CC#N,,,,test
US20140045872A1,Brc1cccnc1.CCn1c2c(c3ccccc31)CC(C)NC2=O>>CCn1c2c(c3ccccc31)CC(C)N(c1cccnc1)C2=O,I[Cu]I,C1COCCO1,,O=P([O-])([O-])[O-].[K+].[K+].[K+],,test
US20140135359A1,C=CC(=O)Cl.C=CC(=O)c1cc(C(=O)COC(C)=O)c(O)cc1O>>C=CC(=O)c1cc2c(=O)c(O)c(C=C)oc2cc1O,,C1CCOC1,,O,[H-].[Na+],test
US20070093484A1,NN1CCCCC1.[N-]=[N+]=NCc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1C(=O)Cl>>[N-]=[N+]=NCc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)nc1C(=O)NN1CCCCC1,,ClCCl,,,,test
US20140005222A1,CC(C)(C)[Si](C)(C)Cl.OCC1CCCNC1>>CC(C)(C)[Si](C)(C)OCC1CCCNC1,,ClCCl,,CCN(CC)CC,,test
US20060160879A1,CCOC(=O)c1c(NC(=O)CCc2ccc(OC)cc2)c2ccc(-c3cc(F)cc(F)c3)cc2n1Cc1cccc(Cl)c1>>COc1ccc(CCC(=O)Nc2c(C(=O)O)n(Cc3cccc(Cl)c3)c3cc(-c4cc(F)cc(F)c4)ccc23)cc1,,C1COCCO1,,[K+].[OH-],,test
US20110207711A1,CC(C)(C)OC(=O)N1CCCC(CBr)C1.Cn1cc(-c2cc(O)c3c(Br)cnn3c2)cn1>>Cn1cc(-c2cc(OCC3CCCN(C(=O)OC(C)(C)C)C3)c3c(Br)cnn3c2)cn1,,CN(C)C=O,,[H-].[Na+],,test
US20040058903A1,COC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1>>O=C(O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1,,C1CCOC1,CO,[Na+].[OH-],,test
US20140221311A1,CCS(=O)(=O)Cl.Nc1ccccc1Br>>CCS(=O)(=O)Nc1ccccc1Br,,O,c1ccncc1,,,test
US05624950,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC1(C)CCC(=O)C2CNCC21>>CC(C)(C)OC(=O)N1CC2C(=O)CCC(C)(C)C2C1,CN(C)c1ccncc1,ClCCl,,CCN(CC)CC,Cl,test
US04725610,Cc1oc(-c2ccccc2)nc1C(=O)CBr.N#Cc1ccc(O)cc1>>Cc1oc(-c2ccccc2)nc1C(=O)COc1ccc(C#N)cc1,,CCC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US06399616B1,C1CNCCN1.Clc1nccc2occc12>>c1cc2occc2c(N2CCNCC2)n1,,CCO,,ClCCl,O,test
US20150291595A1,CN(C)CCCO.COc1cc([N+](=O)[O-])ccc1Cl>>COc1cc([N+](=O)[O-])ccc1OCCCN(C)C,,CS(C)=O,O,[H-].[Na+],,test
US20140349989A1,CC(C)(C)OC(=O)N1CC=C(c2cn(-c3ccc([N+](=O)[O-])cc3)c3ccccc23)CC1>>CC(C)(C)OC(=O)N1CCC(c2cn(-c3ccc(N)cc3)c3ccccc23)CC1,[Pd],CCOC(C)=O,CO,,,test
US20130090323A1,CS(=O)(=O)Cl.Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1-c1cncc(N)c1>>Cc1c(-c2ccccn2)nc2cc(F)cc(F)c2c1Nc1cc(N2CCOCC2)ncc1-c1cncc(NS(C)(=O)=O)c1,,ClCCl,c1ccncc1,,,test
US05981533,COc1ccc(CNc2n[nH]c(N=CN(C)C)c2C#N)cc1.Nc1cccc(Cl)c1>>COc1ccc(CNc2n[nH]c3ncnc(Nc4cccc(Cl)c4)c23)cc1,,CCO,,Cl,,test
US20070213314A1,C[Si](C)(C)N=[N+]=[N-].N#CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Cc1cc(C(F)(F)F)ccc1Br>>FC(F)(F)c1cc(CN(Cc2cc(C(F)(F)F)ccc2Br)c2nn[nH]n2)cc(C(F)(F)F)c1,,COC(C)(C)C,,CCN(CC)CC,[Na+].[OH-],test
US20100069360A1,C#Cc1cccc(CC(=O)N2CCOCC2)c1.CC1(C)OBOC1(C)C>>CC1(C)OB(/C=C/c2cccc(CC(=O)N3CCOCC3)c2)OC1(C)C,,ClCCl,,,,test
US20070043036A1,C=Cc1cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n(-c2cccc(C(F)(F)F)c2)c1C.CO>>COC(C)c1cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)n(-c2cccc(C(F)(F)F)c2)c1C,,CO,,O=S(=O)(O)O,O=C([O-])O.[Na+],test
US20100197683A1,CCCc1c(Cc2ccc(-c3ccccc3C#N)cc2)c(=O)n([C@@H]2CC[C@@H](OC3CC3(C)O[Si](CC)(CC)CC)CC2)c2ccnn12.O=C([O-])O.[NH3+]O>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n([C@@H]2CC[C@@H](O[C@@H]3C[C@@]3(C)O)CC2)c2ccnn12,,CCOC(C)=O,,CS(C)=O,[Cl-].[Na+],test
US20140206669A1,CN(C)C=O.COC1=C[C@]23CCCN2CCc2cc4c(cc2[C@@H]3[C@@H]1OC(=O)[C@@](O)(CCCC(C)(C)O)CC(=O)O)OCO4>>COC(=O)C[C@](O)(CCCC(C)(C)O)C(=O)O[C@@H]1C(OC)=C[C@]23CCCN2CCc2cc4c(cc2[C@H]13)OCO4,,O,,CCN(C(C)C)C(C)C,,test
US20110263582A1,CS(=O)(=O)Cl.C[C@H](N1CC[C@](CCN)(c2ccc(F)cc2)OC1=O)C(C)(C)C>>C[C@H](N1CC[C@](CCNS(C)(=O)=O)(c2ccc(F)cc2)OC1=O)C(C)(C)C,,ClCCl,,CCN(CC)CC,,test
US20120208817A1,CCOC(=O)c1ccccn1.Cl[Mg]Cc1ccccc1>>O=C(Cc1ccccc1)c1ccccn1,,C1CCOC1,,[Cl-].[NH4+],,test
US20160052884A1,CC(C)(C)OC(=O)c1ccc(N)cc1.COc1cn(C(CCF)C(=O)O)c(=O)cc1-c1cc(Cl)ccc1C#N>>COc1cn(C(CCF)C(=O)Nc2ccc(C(=O)OC(C)(C)C)cc2)c(=O)cc1-c1cc(Cl)ccc1C#N,,CN(C)C=O,,CC(C)N=C=NC(C)C,,test
US20160122345A1,CCS(=O)(=O)c1ccc([C@@H](N)COC)cc1.CC[C@H]1c2ncc(C(=O)O)cc2CN1C(=O)OC(C)(C)C>>CC[C@H]1c2ncc(C(=O)N[C@@H](COC)c3ccc(S(=O)(=O)CC)cc3)cc2CN1C(=O)OC(C)(C)C,,CN(C)C=O,O,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US05554757,Cc1c(Br)cnc(NCc2ccc(-c3ccccc3C#N)cc2)c1NC(=O)C1CC1>>Cc1c(Br)cnc2c1nc(C1CC1)n2Cc1ccc(-c2ccccc2C#N)cc1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,O,test
US20140371238A1,CC(C)(C)OC(=O)N1CCC(n2c(-c3ccccc3Cl)nc3cccnc32)CC1>>Clc1ccccc1-c1nc2cccnc2n1C1CCNCC1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US05475003,O=C1CCCc2ccc([N+](=O)[O-])cc21>>Nc1ccc2c(c1)CCCC2,[Pd],CCO,CO,Cl,O,test
US05972965,C1CCOC1.CCN(CC)CC.CCOC(C)=O.COc1cccc(CC(CCO)C(O)c2nc(-c3ccccc3)c(-c3ccccc3)o2)c1>>COc1cccc(CC2CCN(Cc3ccccc3)C2c2nc(-c3ccccc3)c(-c3ccccc3)o2)c1,,CCOC(C)=O,,CS(=O)(=O)Cl,,test
US20130053366A1,Cc1ccc2[nH]c3c(c2c1)CN(C)CC3.ClCCl.Nc1ccccc1>>Cc1ccc2c(c1)c1c(n2CNc2ccccc2)CCN(C)C1,,O,,[K+].[OH-],,test
US20090203674A1,CC#CCOc1ncnc(Cl)c1F.CC1(C)CCNC1>>CC#CCOc1ncnc(N2CCC(C)(C)C2)c1F,,CCOC(C)=O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20080009524A1,COS(=O)(=O)[O-].Nc1ccc(Br)cc1C(=O)O>>COC(=O)c1cc(Br)ccc1N,,CN(C)C=O,,CCN(CC)CC,,test
US20070270588A1,CCI.COCCn1ccc2c(C)nc(Nc3ccc(C(C)C)cc3Br)nc21>>CCN(c1nc(C)c2ccn(CCOC)c2n1)c1ccc(C(C)C)cc1Br,,C1CCOC1,CCOC(C)=O,[Na+].[OH-],,test
US20040044057A1,CCOC(=O)/C=C/Cc1cccc(OC)c1OC>>CCOC(=O)C=CCc1cccc(OC)c1OC,[Pd],CCO,,,,test
US20100286178A1,N#Cc1cnc2[nH]cc(C(=O)c3c(F)ccc(N)c3F)c2c1.O=S(=O)(Cl)c1cc(F)ccc1F>>N#Cc1cnc2[nH]cc(C(=O)c3c(F)ccc(NS(=O)(=O)c4cc(F)ccc4F)c3F)c2c1,,C1CCOC1,c1ccncc1,Cl,,test
US04618617,C1COCCN1.CC(c1ccc(-c2ccccc2)c(F)c1)c1nc(CCl)no1>>CC(c1ccc(-c2ccccc2)c(F)c1)c1nc(CN2CCOCC2)no1,,CN(C)C=O,,,,test
US20150191439A1,O=C1CCC(=O)N1Br.c1cc2cc(CNC34CC5CC(CC(C5)C3)C4)sc2s1>>Brc1cc2cc(CNC34CC5CC(CC(C5)C3)C4)sc2s1,,CN(C)C=O,,,,test
US20060154931A1,CI.COc1ccc(-n2cncc2-c2ccncc2)cc1>>COc1ccc(-n2c(-c3ccncc3)cnc2C)cc1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20160194304A1,COC(=O)c1ccn2c1CCCC2>>O=C(O)c1ccn2c1CCCC2,,C1COCCO1,O,Cl,[Li+].[OH-],test
US06300363B1,CCOC(=O)n1c(C(=O)c2cccc(OC)c2)c(N)c2ccc(Cl)cc21>>COc1cccc(C(=O)c2[nH]c3cc(Cl)ccc3c2N)c1,,CCO,,O=C([O-])[O-].[K+].[K+],,test
US20100099561A1,CI.Cc1c(C(F)(F)F)c2ccccc2[nH]c1=O>>Cc1c(C(F)(F)F)c2ccccc2n(C)c1=O,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20130338134A1,CCN1C(=O)N(c2c(F)c(OC)cc(OC)c2F)Cc2cnc3[nH]ccc3c21.O=S(=O)(Cl)c1ccccc1>>CCN1C(=O)N(c2c(F)c(OC)cc(OC)c2F)Cc2cnc3c(ccn3S(=O)(=O)c3ccccc3)c21,,CN(C)C=O,,[H-].[Na+],,test
US20070105920A1,COc1c(Cl)cc(Cl)cc1C(=O)CBr.NC(N)=S>>COc1c(Cl)cc(Cl)cc1-c1csc(N)n1,,CCO,,,,test
US20140243336A1,COC=CC#N.NNc1ccccn1>>Nc1ccn(-c2ccccn2)n1,,CCO,,C,C[O-].[Na+],test
US20130059849A1,CCOC(=O)C(=O)CC(=O)C1CC1.Cc1cc(N)n(C2CCC2)n1>>CCOC(=O)c1cc(C2CC2)nc2c1c(C)nn2C1CCC1,,c1ccccc1,,,,test
US20120010190A1,CCCC(CC(=O)c1ccc(OC)nc1)c1ccc(Br)cc1F>>CCCC(CC(=O)c1ccc(=O)[nH]c1)c1ccc(Br)cc1F,,C1COCCO1,,Cl,,test
US04308378,COC(=O)CC(=O)CC(O)/C=C/c1c(Cl)cc(Cl)cc1OCc1ccccc1>>COC(=O)CC(O)CC(O)/C=C/c1c(Cl)cc(Cl)cc1OCc1ccccc1,,CCO,O,Cl,[BH4-].[Na+],test
US20070197571A1,CC(C)Oc1cccc(Br)n1.CN(C)C=O>>CC(C)Oc1cccc(C=O)n1,,C1CCOC1,,[Li]CCCC,,test
US20050054658A1,C(=C[C@@H]1CC[C@@H](Nc2ncnc3[nH]ncc23)CC1)CCc1ccccc1>>c1ccc(CCCC[C@@H]2CC[C@@H](Nc3ncnc4[nH]ncc34)CC2)cc1,[Pd],CCO,,,,test
US20150329523A1,COCCOCCOCCOCCOc1cc(N)cc(OC)c1.Cc1ccc(-n2nc(C(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc(Cl)n3)c3ccccc23)cc1>>COCCOCCOCCOCCOc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(C(C)C)nn4-c4ccc(C)cc4)c4ccccc34)n2)cc(OC)c1,,CCOC(C)=O,CN(C)C=O,C1CCOC1,,test
US20100125062A1,Clc1nc2ccccc2s1.Nc1ccc(Oc2ncncc2C2CCOCC2)cc1>>c1ccc2sc(Nc3ccc(Oc4ncncc4C4CCOCC4)cc3)nc2c1,,CC(C)O,,,,test
US04772600,CC(C)O.CN1CCCC1CCNC(=O)Cn1c(-c2ccc(Cl)cc2)nc2cccnc21.Cl>>CN1CCCC1CCNC(=O)Cn1c(-c2ccc(Cl)cc2)nc2cccnc21.Cl.O,,CC(C)O,,CC(C)OC(C)C,,test
US20080281092A1,NCCOCCOCC(=O)O.O=C1OCC(O)C(O)C1(O)CO>>O=C(O)COCCOCCNC(=O)C(O)C(O)C(O)C(O)CO,,CO,,O=C([O-])[O-].[Na+].[Na+],,test
US20120196872A1,COC(=O)CN1C(=O)[C@H](CC2CCCCCC2)N(C(=O)OC(C)(C)C)CC1c1cc(F)cc(F)c1>>CC(C)(C)OC(=O)N1CC(c2cc(F)cc(F)c2)N(CC(=O)O)C(=O)[C@@H]1CC1CCCCCC1,,C1CCOC1,O,[Li+].[OH-],,test
US05401868,CCC(=O)OCOC(=O)Cl.CCC(C)O>>CCC(=O)OCOC(=O)OC(C)CC,,ClC(Cl)Cl,,CN1CCOCC1,,test
US20080004323A1,CC(=O)Cl.Oc1ccc(N=C(C=COc2ccccc2)Oc2ccccc2)cc1>>CC(=O)Oc1ccc(N=C(C=COc2ccccc2)Oc2ccccc2)cc1,,COC(C)(C)C,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20070191333A1,COC(=O)C1CC(=O)N(C(C)c2ccccc2)C1>>CC(c1ccccc1)N1CCC(CO)C1,,CCOCC,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20020128284A1,COC[C@H]1[C@H]2CC[C@@H](C[C@@H]1c1ccc(Cl)c(Cl)c1)N2C.O=S(=O)(O)O>>COC[C@H]1[C@H]2CC[C@@H](C[C@@H]1c1ccc(Cl)c(Cl)c1)N2C.O=S(=O)(O)O,,CC(C)O,,,,test
US20060052445A1,Fc1ccccc1Sc1ccc(Cl)nc1.O=C(OO)c1cccc(Cl)c1>>O=S(c1ccc(Cl)nc1)c1ccccc1F,,ClCCl,,[Na+].[OH-],,test
US20080027093A1,C[C@@H](C1CCC(NC(=O)OCc2ccccc2)CC1)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CC[C@H](F)C1>>C[C@@H](C1CCC(N)CC1)[C@H](NC(=O)OC(C)(C)C)C(=O)N1CC[C@H](F)C1,[Pd],CO,,[H][H],,test
US20120065214A1,COC(=O)c1ccc(C)c(-n2ccnc(NC3(c4cc(F)ccc4O)CC3)c2=O)c1.NC1CC1>>Cc1ccc(C(=O)NC2CC2)cc1-n1ccnc(NC2(c3cc(F)ccc3O)CC2)c1=O,,C1CCOC1,O,CC(C)[Mg]Cl,Cl,test
US20050203127A1,CC(C)(C)OC(=O)NCc1cccc(-n2nc(C(F)(F)F)cc2C(=O)Nc2ccc(N3CCCC3=N)cc2)c1>>N=C1CCCN1c1ccc(NC(=O)c2cc(C(F)(F)F)nn2-c2cccc(CN)c2)cc1,,CCO,CCOCC,Cl,,test
US20100249124A1,COc1ccc(C(C)C(O)(c2ccc3oc(=O)n(C)c3c2)C(F)(F)F)c(Cl)c1>>CC(c1ccc(O)cc1Cl)C(O)(c1ccc2oc(=O)n(C)c2c1)C(F)(F)F,,ClCCl,,,,test
US20130281490A1,CC(C)C(=O)Cl.CCOC(=O)CN(Cc1ccccc1)Cc1ccccc1>>CCOC(=O)[C@@H](C(=O)C(C)C)N(Cc1ccccc1)Cc1ccccc1,,C1CCOC1,,[Li]CCCC,,test
US04657929,CI.COc1ccc(CCNC(=O)C(F)(F)F)cc1N>>CNc1cc(CCNC(=O)C(F)(F)F)ccc1OC,,CN(C)C=O,,O,,test
US20130012492A1,O=C1C(=Cc2ccccn2)COc2ccc(-c3ccc(OC(F)(F)F)cc3)cc21>>O=C1c2cc(-c3ccc(OC(F)(F)F)cc3)ccc2OCC1Cc1ccccn1,[Pd],CCO,,[H][H],,test
US20070129346A1,CC(=O)OC[C@@H](C)C(=O)N(C1CCCCC1)[C@H]1CCN(NC(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)OC(C)(C)C)C1.O=C(O)C(F)(F)F>>CC(=O)OC[C@@H](C)C(=O)N(C1CCCCC1)[C@H]1CCN(NC(=O)[C@H](N)Cc2ccc(Cl)cc2)C1.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20080027053A1,CC(=O)N(C[C@H]1CN(c2ccc(N3Cc4cn(C)nc4C3)c(F)c2)C(=O)O1)C(=O)OCOC(=O)CN(C)C(=O)OC(C)(C)C>>CNCC(=O)OCOC(=O)N(C[C@H]1CN(c2ccc(N3Cc4cn(C)nc4C3)c(F)c2)C(=O)O1)C(C)=O,,ClCCl,,CCOCC,Cl,test
US20120082702A1,Cc1cnc(NC(=O)Oc2ccccc2)s1.NC(=O)c1cnc(N2CCC[C@@H](N)C2)cc1Nc1ccc(C(=O)N2CCOCC2)cc1>>Cc1cnc(NC(=O)N[C@@H]2CCCN(c3cc(Nc4ccc(C(=O)N5CCOCC5)cc4)c(C(N)=O)cn3)C2)s1,,C1CCOC1,,CCN(CC)CC,,test
US20150031674A1,CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CCOC(=O)Cc1ccc(Br)cc1Cl>>CCOC(=O)Cc1ccc(B2OC(C)(C)C(C)(C)O2)cc1Cl,,C1COCCO1,,CC(=O)[O-].[K+],,test
US20150225397A1,CC1=C2CCC[C@H](O)[C@@]2(c2ccc(F)cc2)CCC1=O>>C[C@@H]1C(=O)CC[C@@]2(c3ccc(F)cc3)[C@H]1CCC[C@@H]2O,[Pd],c1ccncc1,,C1CCOC1,,test
US20140235533A1,N#Cc1cc(I)ccc1F.c1nc[nH]n1>>N#Cc1cc(I)ccc1-n1cncn1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100305122A1,BrCCOCc1ccccc1.OC1CCOC1>>c1ccc(COCCOC2CCOC2)cc1,,C1CCOC1,,[H-].[Na+],,test
US20020173527A1,CCCc1ccc2c(C(=O)OC)ccc(OC)c2n1>>CCCc1ccc2c(C(=O)O)ccc(OC)c2n1,,O,,CO,O=C([O-])[O-].[K+].[K+],test
US20080214598A1,CC(C)(C)OC(=O)N(Cc1ccc(Cl)c(CO)c1)C1CC1>>CC(C)(C)OC(=O)N(Cc1ccc(Cl)c(C=O)c1)C1CC1,O=[Mn]=O,CC#N,,,,test
US20140221361A1,C=C(COCCN1CCOCC1)[C@@H]1CC[C@]2(C(=O)OCc3ccccc3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)O)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12.C[Si](C)(C)C=[N+]=[N-]>>C=C(COCCN1CCOCC1)[C@@H]1CC[C@]2(C(=O)OCc3ccccc3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(c6ccc(C(=O)OC)cc6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12,,CO,Cc1ccccc1,,,test
US20070060587A1,BrCc1csc(-c2ccccc2)c1.O=C1NC(=O)c2ccccc21>>O=C1c2ccccc2C(=O)N1Cc1csc(-c2ccccc2)c1,,CN(C)C=O,,[K],,test
US20110230463A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.O=C1CCOc2cc(O)ccc21>>CC(C)(C)[Si](Oc1ccc2c(c1)OCCC2=O)(c1ccccc1)c1ccccc1,,CN(C)C=O,,O,c1c[nH]cn1,test
US20070265345A1,O=CNc1ccc(Br)cc1F.O=[N+]([O-])O>>O=CNc1c(F)cc(Br)cc1[N+](=O)[O-],,O=S(=O)(O)O,,,,test
US20050106691A1,CCC(=CC(=O)OC)CC>>CCC(=CC(=O)O)CC,,C1COCCO1,,Cl,[Na+].[OH-],test
US20090253709A1,CCCCN.O=C(CCl)Nc1ccc2c(c1)C(=O)c1cc(NC(=O)CCl)ccc1C2=O.c1ccncc1>>CCCCNCC(=O)Nc1ccc2c(c1)C(=O)c1cc(NC(=O)CNCCCC)ccc1C2=O,,CN(C)C=O,,,,test
US20090275574A1,O=C(OCc1ccccc1)N1CCC(N2C(=O)CO[C@@H]3CCC(F)(F)C[C@H]32)CC1>>O=C1CO[C@@H]2CCC(F)(F)C[C@H]2N1C1CCNCC1,[Pd],CC(C)O,,,,test
US20090041669A1,COC(=O)Cc1cc(OC)c(OC)cc1CN(C(C)=O)c1ccccc1>>COc1cc(CC(=O)O)c(CN(C(C)=O)c2ccccc2)cc1OC,,CO,,[Li+].[OH-],,test
US20050026973A1,CCCC(=O)Cl.COC(=O)C(N)Cc1ccc(OCCn2c(=O)sc3cc(C(=O)c4ccccc4)ccc32)cc1>>CCCC(=O)NC(Cc1ccc(OCCn2c(=O)sc3cc(C(=O)c4ccccc4)ccc32)cc1)C(=O)OC,,CCOC(C)=O,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20090270454A1,CCOC(=O)c1cnc(S(=O)(=O)N2CCC(Sc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)CC2)[nH]1.C[Mg]Cl>>CC(C)(C)c1cc(SC2CCN(S(=O)(=O)c3ncc(C(C)(C)O)[nH]3)CC2)cc(C(C)(C)C)c1O,,C1CCOC1,,,,test
US20130109679A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CC(O)C(C)CN>>CC(O)C(C)CNC(=O)OC(C)(C)C,,ClCCl,,,,test
US20110144056A1,Brc1ccc(-c2cc[nH]n2)cc1.CCI>>CCn1ccc(-c2ccc(Br)cc2)n1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20100168082A1,CCn1nc(NC(=O)n2ccc3cc(Oc4ccnc(CN(C)C(=O)OC(C)(C)C)n4)ccc32)cc1C1CC1>>CCn1nc(NC(=O)n2ccc3cc(Oc4ccnc(CNC)n4)ccc32)cc1C1CC1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110184188A1,CN(C)C=C(C(=O)c1ccc(Cl)cc1)n1cnc(C(F)(F)F)n1>>FC(F)(F)c1nc[nH]n1,,CCO,,NN,O,test
US20130029979A1,CC(C)(C)OC(=O)Nc1cc(F)c2c(c1)OC(C)(C)N=C2c1ccc(F)cc1>>CC1(C)N=C(c2ccc(F)cc2)c2c(F)cc(N)cc2O1,,O=C(O)C(F)(F)F,,O=C([O-])O.[Na+],,test
US20120202785A1,Cc1cccc(Nc2ccccc2)c1[N+](=O)[O-]>>Cc1cccc(Nc2ccccc2)c1N,[Pd],CCOC(C)=O,,,,test
US20140329794A1,Cc1c(N)cccc1C(=O)NCC(O)CN1CCc2ccccc2C1.O=C1CCOCC1>>Cc1c(NC2CCOCC2)cccc1C(=O)NCC(O)CN1CCc2ccccc2C1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20060205774A1,CC(C)(C)OC(=O)N1CCC(=O)CC1.CC(C)N1CCC(Oc2ccc(I)cc2)CC1>>CC(C)N1CCC(Oc2ccc(C3(O)CCN(C(=O)OC(C)(C)C)CC3)cc2)CC1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US06156892,CCOC(=O)C1(C(=O)OCC)C(n2cnc3c(Cl)nc(N)nc32)C1(Cl)Cl.Nc1nc(Cl)c2[nH]cnc2n1>>CCOC(=O)C(=CC(Cl)(Cl)Cl)C(=O)OCC,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US20150239900A1,COC(=O)CC1NCCNC1=O>>OCCC1CNCCN1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20090306016A1,COc1cccc(C=CCCCCCOc2ccccc2)c1>>COc1cccc(CCCCCCCOc2ccccc2)c1,[Pd],CCOC(C)=O,,,,test
US20030109499A1,NC1CC1.Nc1nc(O)cc(Cl)n1>>Nc1nc(O)cc(NC2CC2)n1,,CCO,,O,,test
US20070203155A1,COC(=O)COc1ccc(O)cc1C.ClCc1nc(-c2cccnc2)c(Br)s1>>COC(=O)COc1ccc(OCc2nc(-c3cccnc3)c(Br)s2)cc1C,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20110313175A1,C=CCCCCCCCCC(=S)Oc1ccccn1.CCCCC(CC)C[Mg]Br>>C=CCCCCCCCCC(=O)CC(CC)CCCC,,C1CCOC1,,CCOCC,,test
US05998433,C=O.CCNCC.O=C(CCCCCc1ccccc1)N1CCc2ccoc2C1>>CCN(CC)Cc1cc2c(o1)CN(C(=O)CCCCCc1ccccc1)CC2,,CC(=O)O,,,,test
US04050921,Cc1ccc(CSc2cccc[n+]2[O-])cc1C.O=C(OO)c1cccc(Cl)c1>>Cc1ccc(CS(=O)c2cccc[n+]2[O-])cc1C,,ClC(Cl)Cl,,,,test
US05266556,O=[N+]([O-])c1ccc2cnn(-c3ncc(C(F)(F)F)cc3Cl)c2c1>>Nc1ccc2cnn(-c3ncc(C(F)(F)F)cc3Cl)c2c1,[Fe],CC(=O)O,,O,,test
US20090221551A1,O=[N+]([O-])c1c(Cl)nc2ccccc2c1NCCCO>>Nc1c(Cl)nc2ccccc2c1NCCCO,[Pt],CC#N,,,,test
US05756528,BrC(Br)(Br)Br.CC(O)c1ccc(C#N)cc1>>CC(Br)c1ccc(C#N)cc1,,CCOCC,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20090093456A1,CCN(CC)S(F)(F)F.CN1CCC(C(O)c2ccc(Br)cc2)C1>>CN1CCC(C(F)c2ccc(Br)cc2)C1,,ClCCl,,,,test
US20140343030A1,CC1(C)OB(c2cn[nH]c2)OC1(C)C.C[C@H](NC(=O)c1cc(F)c(N2CC(=CC#N)C2)cc1F)C(F)(F)F>>C[C@H](NC(=O)c1cc(F)c(N2CC(CC#N)(n3cc(B4OC(C)(C)C(C)(C)O4)cn3)C2)cc1F)C(F)(F)F,,CC#N,,C1CCC2=NCCCN2CC1,,test
US20140107141A1,CC(=O)c1ccccc1.CC1(C)CC(=O)CC(=O)C1.Nc1cc(C(F)(F)F)n[nH]1>>CC1(C)CC(=O)C2=C(C1)Nc1n[nH]c(C(F)(F)F)c1C2(C)c1ccccc1,,O=C(O)C(F)(F)F,,,,test
US05780677,NC(=O)CC[C@H](N)C(=O)O.O=C(Cl)CCl>>NC(=O)CC[C@H](NC(=O)CCl)C(=O)O,,Cc1ccccc1,,O,[Na+].[OH-],test
US20070244088A1,CCOC(=O)c1cnc(N2CCNCC2)c(Cl)c1.O=C=Nc1ccccc1>>CCOC(=O)c1cnc(N2CCN(C(=O)Nc3ccccc3)CC2)c(Cl)c1,,CC#N,,,,test
US20100022477A1,O=P(Br)(Br)Br.OCc1ccc2c(Br)c(I)ccc2c1>>BrCc1ccc2c(Br)c(I)ccc2c1,,ClCCl,,CN(C)C=O,,test
US20090312338A1,COC(=O)C1CN(C(=O)OC(C)(C)C)CCC1C>>CC1CCN(C(=O)OC(C)(C)C)CC1CO,,C1CCOC1,,CC(C)C[AlH]CC(C)C,,test
US20160139133A1,CCOC(=O)COCCOC(COc1cccc(C(=O)NCCC(=O)OC(C)(C)C)c1)N=[N+]=[N-]>>CC(C)(C)OC(=O)CCNC(=O)c1cccc(OCC(N=[N+]=[N-])OCCOCC(=O)O)c1,,CCO,,[Na+].[OH-],,test
US20110015175A1,C=CCBr.O=C(O)Cc1ccc(F)cc1>>C=CCC(C(=O)O)c1ccc(F)cc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Na+],,test
US20030195211A1,O=c1c2c(Cl)cccc2nc(CCl)n1-c1ccccc1Cl.Sc1ncnc2nc[nH]c12>>O=c1c2c(Cl)cccc2nc(CSc2ncnc3[nH]cnc23)n1-c1ccccc1Cl,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US08017608B2,CC(=Cc1ccc(S(C)(=O)=O)c(C(F)(F)F)c1)[N+](=O)[O-]>>CC(=O)Cc1ccc(S(C)(=O)=O)c(C(F)(F)F)c1,[Fe],,,CC(=O)O,,test
US20020128286A1,Cn1cc(C(=O)CCl)cc1C(=O)c1ccc(S(C)=O)cc1.OO>>Cn1cc(C(=O)CCl)cc1C(=O)c1ccc(S(C)(=O)=O)cc1,,CC(=O)O,,,,test
US06355642B1,O=C1Nc2cccc3c2C1(CCCCBr)CCC3.O=[N+]([O-])O>>O=C1Nc2ccc([N+](=O)[O-])c3c2C1(CCCCBr)CCC3,,CC(=O)O,,CC(=O)OC(C)=O,,test
US06645983B1,COc1ccc(-c2c[nH]c3c(OC)ccc(OC)c3c2=O)cc1.N#CCCCCl>>COc1ccc(-c2cn(CCCC#N)c3c(OC)ccc(OC)c3c2=O)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US04668697,CI.OCc1ccc2sccc2c1>>COCc1ccc2sccc2c1,,CS(C)=O,,[K+].[OH-],,test
US20130109662A1,C=C1CC(=O)O1.COC(=O)[C@@H](N)CO>>COC(=O)[C@H](CO)NC(=O)CC(C)=O,,C1CCOC1,,Cl,O=C([O-])O.[Na+],test
US20020012977A1,Cc1ccc(-c2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)ncnc2OCCOc2ncc(Br)cn2)cc1.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO>>Cc1ccc(-c2c(NS(=O)(=O)c3ccc(C(C)(C)CO)cc3)ncnc2OCCOc2ncc(Br)cn2)cc1,,CS(C)=O,,,,test
US20060116382A1,CCOC(=O)C1(CC=C(C)C)CCCN(C(=O)OC(C)(C)C)C1.O=[O+][O-]>>CCOC(=O)C1(CC=O)CCCN(C(=O)OC(C)(C)C)C1,,ClCCl,,,,test
US20020094989A1,COc1ccc(COC(=O)C(C)(C)CN2C[C@H](c3cccc(F)c3)[C@@H](CO[Si](C)(C)C(C)(C)C)C2)cc1>>COc1ccc(COC(=O)C(C)(C)CN2C[C@H](c3cccc(F)c3)[C@@H](CO)C2)cc1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US20030036651A1,CCOC(=O)CCCCc1ccncc1.O=Cc1cccnc1Nc1cccc([N+](=O)[O-])c1>>O=c1c(CCCc2ccncc2)cc2cccnc2n1-c1cccc([N+](=O)[O-])c1,,CCO,CN(C)C=O,CC(C)[N-]C(C)C.[Li+],,test
US20160024110A1,CCOC(=O)C(=O)c1cc(F)ccc1F.ClC(Cl)(Cl)Cl>>CCOC(=O)C(=C(Cl)Cl)c1cc(F)ccc1F,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US04797470,Cc1cc(OC(=O)Oc2ccccc2)cc(C)c1C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H](C)C(=O)NCCCc1ccccc1.Cl>>Cc1cc(OC(=O)Oc2ccccc2)cc(C)c1C[C@H](N)C(=O)N[C@H](C)C(=O)NCCCc1ccccc1.Cl,,CC(=O)O,,C1COCCO1,,test
US05244886,CCCC[Sn](CCCC)(CCCC)c1cccnc1.Oc1ccc(Br)cc1>>Oc1ccc(-c2cccnc2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,,,test
US04772600,N.O=C(O)Cn1c(-c2ccc(F)cc2)nc2cccnc21>>NC(=O)Cn1c(-c2ccc(F)cc2)nc2cccnc21.O,,C1CCOC1,,O=C(n1ccnc1)n1ccnc1,,test
US05210204,CCc1nc2nc(C)cc(C)c2[nH]1.COC(=O)c1ccccc1-c1ccc(CBr)cc1>>CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2C(=O)OC)cc1,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20070185104A1,N#CCC(=O)Nc1ccccc1O>>N#CCc1nc2ccccc2o1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US20050004140A1,C[C@H](Nc1cncc(Cl)n1)c1ccc(Br)cc1.c1cncc(B2OCCCO2)c1>>C[C@H](Nc1cncc(Cl)n1)c1ccc(-c2cccnc2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CO,ClCCl,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US20100063108A1,CCc1cc(C#N)cc(C)c1CCC(=O)OC(C)(C)C.NO>>CCc1cc(C(=N)NO)cc(C)c1CCC(=O)OC(C)(C)C,,CO,,CCN(CC)CC,Cl,test
US20050215572A1,CC1(C)C(=O)NC(=O)c2cc(N)ccc21>>CC1(C)CNCc2cc(N)ccc21,,C1CCOC1,,[Na+].[OH-],[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20030114666A1,C[C@@H](c1ccccc1)N1CCC(C(N)c2cocn2)C1>>NC(c1cocn1)C1CCNC1,[Pd],CO,,O=C[O-].[NH4+],,test
US20110257170A1,COC(=O)c1cc(Cl)c2nc(-n3ccnc3)nc(N3CCOCC3)c2n1.COCCN>>COCCNc1cc(C(=O)OC)nc2c(N3CCOCC3)nc(-n3ccnc3)nc12,,C1COCCO1,,,,test
US20080171734A1,Cc1cnc(NC(=O)c2cc(OCc3ccccc3)cc(Oc3ccc(C(=O)N4CCC4)nc3)c2)cn1>>Cc1cnc(NC(=O)c2cc(O)cc(Oc3ccc(C(=O)N4CCC4)nc3)c2)cn1,[Pd],CCO,CCOC(C)=O,CO,,test
US20040266774A1,CC(=O)C(C)Br.O=CNc1cccc([N+](=O)[O-])c1>>CC(=O)C(C)N(C=O)c1cccc([N+](=O)[O-])c1,,CCOC(C)=O,CN(C)C=O,O=C([O-])[O-].[K+].[K+],,test
US20060211698A1,Nc1ccc(Br)cc1C=O.O=CCc1ccccc1>>Brc1ccc2ncc(-c3ccccc3)cc2c1,,CCO,,[K+].[OH-],,test
US20090286807A1,CC(C)(CN(C(=O)CBr)c1ccccc1)NC(=O)OC(C)(C)C>>CC(C)(C)OC(=O)N1CC(=O)N(c2ccccc2)CC1(C)C,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20080188521A1,C#CC(O)(CC)CC.N#Cc1cc(-c2ccccc2)c2ccc(CCN=[N+]=[N-])cc2n1>>CCC(O)(CC)c1cn(CCc2ccc3c(-c4ccccc4)cc(C#N)nc3c2)nn1,I[Cu]I,C1CCOC1,,CCN(C(C)C)C(C)C,,test
US04842640,C#CCBr.CC(C)(C)c1nn(-c2cc(O)c(Cl)cc2F)c(=O)o1>>C#CCOc1cc(-n2nc(C(C)(C)C)oc2=O)c(F)cc1Cl,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20080161365A1,CN(C)C(OC(C)(C)C)OC(C)(C)C.O=Cc1ccc(C(=O)O)cc1>>CC(C)(C)OC(=O)c1ccc(C=O)cc1,,CCOC(C)=O,c1ccccc1,,,test
US06136823,CCOC(=O)c1cn(-c2cc([N+](=O)[O-])c(F)cc2C)c2c(C)c([N+](=O)[O-])c(F)cc2c1=O>>CCOC(=O)c1cn(-c2cc(N)c(F)cc2C)c2c(C)c(N)c(F)cc2c1=O,[Fe],CC(=O)O,,,,test
US20160016936A1,CC(C)c1c(N)ncnc1Cl.Cc1cc(-c2cn(CCN3CCC3)c([C@H]3CCNC[C@H]3F)n2)ccc1F>>Cc1cc(-c2cn(CCN3CCC3)c([C@H]3CCN(c4ncnc(N)c4C(C)C)C[C@H]3F)n2)ccc1F,,CN1CCCC1=O,,C1CCC2=NCCCN2CC1,,test
US20110039835A1,C=C(C(=O)OC)N1C(=O)c2ccccc2C1=O.CC(C)(C)OC(=O)NCCN>>COC(=O)C(CNCCNC(=O)OC(C)(C)C)N1C(=O)c2ccccc2C1=O,,CC#N,,ClCCl,O=C([O-])[O-].[K+].[K+],test
US20080045526A1,Cc1ccc2c(n1)COC2=O.O=C(OO)c1cccc(Cl)c1>>Cc1ccc2c([n+]1[O-])COC2=O,,ClC(Cl)Cl,ClCCl,,,test
US20120202785A1,CCN(C(C)C)C(C)C.C[C@H](N)c1nc2ccc(F)cc2n1-c1ccccn1.FC(F)(F)c1nc(Cl)c2nc[nH]c2n1>>C[C@H](Nc1nc(C(F)(F)F)nc2[nH]cnc12)c1nc2ccc(F)cc2n1-c1ccccn1.N,,CC(C)O,,,,test
US20110112096A1,Cc1cc([N+](=O)[O-])c(C)cc1-c1cnco1>>Cc1cc(-c2cnco2)c(C)cc1N,[Pd],CO,,,,test
US20110178089A1,COC(=O)CCC(N)CCC(=O)OC.COC(=O)CNC(=O)c1cc(Cl)c(Oc2ccncc2C(=O)N2CCN(C3CC3)c3ccccc32)cc1Cl>>COC(=O)CCC(CCC(=O)OC)NC(=O)c1cc(Cl)c(Oc2ccncc2C(=O)N2CCN(C3CC3)c3ccccc32)cc1Cl,,CCCCCCC,CCOC(C)=O,,,test
US05144045,C=C(CBr)C(=O)OCC.CCCCCCCCCCCCCCCCO>>C=C(COCCCCCCCCCCCCCCCC)C(=O)OCC,,ClCCl,,CN(C)c1ccccn1,,test
US20080132459A1,O=C(O)c1ccc(OCCN2CCOCC2)cc1.O=S(Cl)Cl>>O=C(Cl)c1ccc(OCCN2CCOCC2)cc1,CN(C)C=O,,,,,test
US20130109029A1,Brc1ccc(Br)c2snnc12.CC1(C)OB(c2cccc3c2C(CCCCCCBr)(CCCCCCBr)c2ccccc2-3)OC1(C)C>>BrCCCCCCC1(CCCCCCBr)c2ccccc2-c2cccc(-c3ccc(Br)c4snnc34)c21,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O,O=C([O-])[O-].[K+].[K+],test
US05434151,BrCc1ccccc1.CCCOc1c(N)cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)S2)cc1OC>>CCCOc1c(NCc2ccccc2)cc([C@H]2CC[C@H](c3cc(OC)c(OC)c(OC)c3)S2)cc1OC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110263647A1,CC(C)(C)OC(=O)N[C@H](CO)Cc1cnc(F)c(Cl)c1.O=S(Cl)Cl>>CC(C)(C)OC(=O)N1[C@@H](Cc2cnc(F)c(Cl)c2)COS1=O,,CC#N,,c1ccncc1,,test
US20110201604A1,Cn1c(Nc2nc3ccc(OC(F)(F)F)cc3s2)nc2cc(C(=O)NCCOCCNC(=O)OCC3c4ccccc4-c4ccccc43)ccc21>>Cn1c(Nc2nc3ccc(OC(F)(F)F)cc3s2)nc2cc(C(=O)NCCOCCN)ccc21,,CN(C)C=O,,C1CCNCC1,,test
US20130158003A1,Cn1cc(-c2ccccc2)nc1CCc1cccc(C#N)n1.OO>>Cn1cc(-c2ccccc2)nc1CCc1cccc(C(N)=O)n1,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20060293337A1,NC1CCN(c2ccc3c(NC(=O)CC4CCCCC4)c(Cl)ccc3n2)CC1.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=C(CC1CCCCC1)Nc1c(Cl)ccc2nc(N3CCC(NS(=O)(=O)C(F)(F)F)CC3)ccc12,,ClCCl,,CCN(CC)CC,,test
US20160229837A1,CC(C)(C)OC(=O)N1CCC(Nc2nc(Cl)ncc2Cl)CC1.Cn1cc2ccc(N)cc2n1>>Cn1cc2ccc(Nc3ncc(Cl)c(NC4CCN(C(=O)OC(C)(C)C)CC4)n3)cc2n1,CC(=O)O[Pd]OC(C)=O,C1COCCO1,,c1ccc(P(c2ccccc2)c2ccc3ccccc3c2-c2c(P(c3ccccc3)c3ccccc3)ccc3ccccc23)cc1,O=C([O-])[O-].[Cs+].[Cs+],test
US20100197665A1,NC(=O)c1cc(F)ccc1[N+](=O)[O-].O=S(O[Na])c1ccccc1>>NC(=O)c1cc(S(=O)(=O)c2ccccc2)ccc1[N+](=O)[O-],,CS(C)=O,,O,,test
US05998433,C=O.CNC.O=C(c1ccccc1)c1ccccc1C(=O)N1CCc2occc2C1>>CN(C)Cc1cc2c(o1)CCN(C(=O)c1ccccc1C(=O)c1ccccc1)C2,,CC(=O)O,,,,test
US20070219220A1,CCCc1nn(CC)c(C(N)=O)c1N.CCOc1ccccc1C(=O)Cl>>CCCc1nn(CC)c(C(N)=O)c1NC(=O)c1ccccc1OCC,,ClCCl,,CCN(CC)CC,N#N,test
US20110257402A1,CC(C)(C(=O)Cl)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.CNc1cnc2c(cnn2Cc2ccccc2)c1-c1ccc(F)cc1C>>Cc1cc(F)ccc1-c1c(N(C)C(=O)C(C)(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cnc2c1cnn2Cc1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090209607A1,COc1c(C(=O)NC(Cc2ccccc2)CN(C(=O)[O-])C(C)(C)C)sc(-c2ccnn2C)c1Br>>COc1c(C(=O)NC(CN)Cc2ccccc2)sc(-c2ccnn2C)c1Br,,ClCCl,O=C(O)C(F)(F)F,,,test
US20050059650A1,Clc1ccccn1.OC1CCNCC1>>OC1CCN(c2ccccn2)CC1,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US05166170,COc1ccc(N)c(-c2cc3ccccc3[nH]2)c1>>COc1ccc(N)c(C2Cc3ccccc3N2)c1,,CC(=O)O,,[Na+].[OH-],,test
US20150191476A1,COC(=O)c1nccc(C(F)(F)F)n1>>O=Cc1nccc(C(F)(F)F)n1,,C1CCOC1,,CC(C)C[AlH]CC(C)C,,test
US20070142443A1,CC(=O)[O-].CC(C)(C)OC(=O)C(OCc1ccccc1)C(=O)Cc1ccccc1.[NH4+]>>CC(=O)O.CC(C)(C)OC(=O)C(OCc1ccccc1)C(N)Cc1ccccc1,,C1CCOC1,,CO,,test
US20040034031A1,CC(C)(C)OC(=O)N1CC=C(c2cccc(O)c2)CC1.CC(C)(C)[Si](C)(C)Cl>>CC(C)(C)OC(=O)N1CC=C(c2cccc(O[Si](C)(C)C(C)(C)C)c2)CC1,CN(C)c1ccccn1,ClCCl,,CCN(CC)CC,CCOC(C)=O,test
US05925761,CCOC(=O)C(C)(C)c1ccccc1.COC(Cl)Cl>>CCOC(=O)C(C)(C)c1ccc(C=O)cc1,Cl[Ti](Cl)(Cl)Cl,ClCCl,,O=S([O-])O.[Na+],,test
US03932428,CI.On1c(C(F)(F)F)nc2ncc(Cl)cc21>>COn1c(C(F)(F)F)nc2ncc(Cl)cc21,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20120202814A1,CC(C)(C)[Si](Cl)(c1ccccc1)c1ccccc1.CS(=O)(=O)c1nc(CCO)cc(Nc2ccc(F)cc2)n1>>CC(C)(C)[Si](OCCc1cc(Nc2ccc(F)cc2)nc(S(C)(=O)=O)n1)(c1ccccc1)c1ccccc1,,CCOC(C)=O,CN(C)C=O,,,test
US06730687B1,COc1ccc(C=C2SC(=O)NC2=O)cc1CC(=O)O.Nc1ccc(C(F)(F)F)cc1>>COc1ccc(C=C2SC(=O)NC2=O)cc1CC(=O)Nc1ccc(C(F)(F)F)cc1,,CN(C)C=O,,CCN(CC)CC,CCOP(=O)(C#N)OCC,test
US20050054851A1,CN1C(=O)N(Cc2cc3cnc(C#N)nc3n2CC(C)(C)C)C(=O)C12CCN(C(=O)O)CC2>>CN1C(=O)N(Cc2cc3cnc(C#N)nc3n2CC(C)(C)C)C(=O)C12CCNCC2,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20070142432A1,COC(=O)CCCN1CC[C@@H](Oc2ccc(Oc3ccccc3)cc2)C1.N>>NC(=O)CCCN1CC[C@@H](Oc2ccc(Oc3ccccc3)cc2)C1,,CO,,,,test
US20070032518A1,COC(=O)c1ccc(CO)c(N)c1>>COC(=O)c1ccc(C=O)c(N)c1,O=[Mn]=O,ClCCl,,,,test
US20110178140A1,CCOC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1SC.NN>>CSc1c(C(=O)NN)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1,,CCO,CCOC(C)=O,O,,test
US20160222028A1,CC(C)(C)OC(=O)NCCBr.CC(C)C(=O)c1ccc(Br)cc1O>>CC(C)C(=O)c1ccc(Br)cc1OCCNC(=O)OC(C)(C)C,,CN(C)C=O,,[I-].[K+],,test
US05189054,CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1N.ClCCl.O=C(Cl)c1ccccc1>>CCOC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1NCC(=O)c1ccccc1,,CCOC(C)=O,ClCCl,CCN(CC)CC,,test
US20040142931A1,N[C@@H](CO)C(=O)O.O=Cc1ccccc1>>O=C(O)[C@H](CO)NCc1ccccc1,,CCOCC,,[Na+].[OH-],,test
US04912117,BrCCc1ccccc1.Cc1ccccc1C1(C=O)CCNCC1.Cl>>Cc1ccc(C(=O)C2CCN(CCc3ccccc3)CC2)cc1.Cl,,CCOC(C)=O,CO,CN(C)C=O,O,test
US20090275538A1,BrCC1CC1.C[C@H]1CNCCN1C1=NC(=O)/C(=C/c2ccc(F)cc2O)S1>>C[C@H]1CN(CC2CC2)CCN1C1=NC(=O)/C(=C/c2ccc(F)cc2O)S1,,CCO,,CCN(C(C)C)C(C)C,,test
US20100152187A1,Nc1nc(CN2CCOCC2)c(C(=O)NCc2ccccc2)s1.O=C(Cl)CCc1ccccc1>>O=C(CCc1ccccc1)Nc1nc(CN2CCOCC2)c(C(=O)NCc2ccccc2)s1,CN(C)c1ccncc1,C1CCOC1,,CCN(CC)CC,,test
US20100081653A1,N#CC(=C1Nc2ccc(C(=O)O)cc2S1)c1nccc(C(F)(F)F)n1.O=S(=O)(O)O>>NC(=O)C(=C1Nc2ccc(C(=O)O)cc2S1)c1nccc(C(F)(F)F)n1,,O=S(=O)(O)O,,O,,test
US20050143443A1,O=C(O)CCc1ccc(Cl)cc1.[Li]C>>CC(=O)CCc1ccc(Cl)cc1,,CCOCC,,,,test
US20050215801A1,O=C(NC[C@H](O)CO)c1ccccc1.O=S(Cl)Cl>>O=C(NCC1COS(=O)O1)c1ccccc1,,ClCCl,O,CCN(CC)CC,Cl,test
US20070072918A1,O=S1(=O)N(CCCBr)c2ccccc2N1c1ccc(Cl)cc1.O[C@@H](CCCl)c1ccccc1>>O=S1(=O)N(c2ccc(Cl)cc2)c2ccccc2N1C(CCCl)c1ccccc1,,C1CCOC1,,CC(C)OC(=O)/N=N/C(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20090264434A1,CC(=O)OC(C)Cn1nc(NC(=O)C(CC2CCOCC2)n2ncc(Oc3c(F)cccc3F)cc2=O)cc1C>>Cc1cc(NC(=O)C(CC2CCOCC2)n2ncc(Oc3c(F)cccc3F)cc2=O)nn1CC(C)O,,C1CCOC1,O,[Li+].[OH-],,test
US20050256140A1,CC(C)(C)OC(N)=O.Cn1cnc(-c2cccc(I)c2)c1-c1cc2c(N)ncnc2s1>>Cn1cnc(-c2cccc(NC(=O)OC(C)(C)C)c2)c1-c1cc2c(N)ncnc2s1,[Cu]I,C1COCCO1,,CNCCNC,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20100249127A1,COc1ncccc1-c1cc2cc(C(=O)O)ccc2[nH]1.NCCCN1CCOCC1>>COc1ncccc1-c1cc2cc(C(=O)NCCCN3CCOCC3)ccc2[nH]1,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20050197328A1,CCn1c(CC#N)nc2cnccc21.COC(OC)N(C)C>>CCn1c(C(C#N)=CN(C)C)nc2cnccc21,,Cc1ccccc1C,,,,test
US04375508,BrCC#CCBr.CCn1c(C)nc2cc(Cl)c(Cl)cc21>>CCn1c(C)[n+](CC#CCBr)c2cc(Cl)c(Cl)cc21.[Br-],,CCOCC,,,,test
US04767769,COc1cccc(CC(N)=O)c1>>COc1cccc(CC#N)c1,,CN(C)C=O,,O=S(Cl)Cl,,test
US20060177943A1,[N-]=[N+]=NCCOCCOCCOCCOCCOCC(=O)OCc1ccccc1>>NCCOCCOCCOCCOCCOCC(=O)O,[Pd],CO,,,,test
US20030219524A1,O.O=C(O)CC(O)(CC(=O)O)C(=O)O>>O.O=C(O)CC(O)(CC(=O)O)C(=O)O,,O,,,,test
US20030004351A1,CNC.NS(=O)(=O)c1ccc(NN=C2C(=O)Nc3ccc(C(=O)Oc4c(F)c(F)c(F)c(F)c4F)cc32)cc1>>CN(C)C(=O)c1ccc2c(c1)C(=NNc1ccc(S(N)(=O)=O)cc1)C(=O)N2,,CC#N,CCO,c1ccncc1,,test
US20060189601A1,COc1ccc2nccc(C3=CCN(C(=O)OC(C)(C)C)CC3)c2n1>>COc1ccc2nccc(C3=CCNCC3)c2n1,,ClCCl,,O=C(O)C(F)(F)F,,test
US04435397,C=CCBr.O=C(O)Cc1ccc(O)cc1>>C=CCOc1ccc(CC(=O)O)cc1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05712300,BrCc1ccccc1.C=C(C)C1(CC(C)C)CCN(CC(=O)OCC)C1=O>>C=C(C)C1(CC(C)C)CCN(C(Cc2ccccc2)C(=O)OCC)C1=O,,C1CCOC1,,CC(C)[N-]C(C)C.[Li+],,test
US04304770,C=CCn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(NC(=O)C(=NOCC)c3csc(NC=O)n3)[C@H]2SC1>>C=CCn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(NC(=O)C(=NOCC)c3csc(N)n3)[C@H]2SC1,,C1CCOC1,CO,Cl,,test
US20080167353A1,BrCc1ccccc1.NCCCO>>NCCCOCc1ccccc1,,C1CCOC1,,[H-].[Na+],,test
US20080275038A1,Cc1ccc(C(=O)Cl)cc1F.Nc1cc(-c2ccncc2F)c(-c2cccnc2)nc1N>>Cc1ccc(C(=O)Nc2cc(-c3ccncc3F)c(-c3cccnc3)nc2N)cc1F,,c1ccncc1,,,,test
US20070010520A1,CC(C)(C)OC(=O)Nc1nc(N2CCN(C(=O)OC(C)(C)C)CC2)cn2nc(-c3ccco3)nc12>>Nc1nc(N2CCNCC2)cn2nc(-c3ccco3)nc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160102096A1,COC(=O)c1cc(CO[Si](C)(C)C(C)(C)C)nc(CN(Cc2nc(OC)ccc2OCc2ccccc2)C(=O)OC(C)(C)C)c1>>COc1ccc(OCc2ccccc2)c(CN(Cc2cc(CO)cc(CO[Si](C)(C)C(C)(C)C)n2)C(=O)OC(C)(C)C)n1,,CCO,,[BH4-].[Na+],,test
US20050176786A1,Nc1cc(-c2cccc(Cl)c2)n[nH]1.O=C1CCC(=O)N1Br>>Nc1[nH]nc(-c2cccc(Cl)c2)c1Br,,C1CCOC1,,,,test
US20080261941A1,Nc1ccc(Br)nc1.O=C(Cl)Oc1ccccc1>>O=C(Nc1ccc(Br)nc1)Oc1ccccc1,,C1CCOC1,,c1ccncc1,,test
US05880270,C(=NC1CCCCC1)=NC1CCCCC1.O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21.O=C1CCC(=O)N1O>>NOCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21,,CN(C)C=O,,,,test
US20050267170A1,COC(=O)c1cc(Cl)ccc1CBr.OCC1CCCCC1>>O=C(O)c1cc(Cl)ccc1COCC1CCCCC1,,C1CCOC1,,Cl,CC(C)(C)[O-].[K+],test
US05972951,CI.Cc1cc(-c2ncc[nH]2)ccc1Br>>Cc1cc(-c2nccn2C)ccc1Br,,C1CCOC1,,[H-].[Na+],,test
US20110178063A1,CC(C)c1sc(CN2CCOCC2)nc1C(=O)O.Nc1cc(-c2cccc3[nH]ccc23)cc2[nH]ncc12>>CC(C)c1sc(CN2CCOCC2)nc1C(=O)Nc1cc(-c2cccc3[nH]ccc23)cc2[nH]ncc12,,CN(C)C=O,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100273744A1,O=C1c2ccccc2C(=O)N1c1ccn(Cc2ccc(I)cc2C(F)(F)F)n1>>Nc1ccn(Cc2ccc(I)cc2C(F)(F)F)n1,,C1CCOC1,,NN,O,test
US05426234,O=C(c1ccc(F)cc1)c1ccc(C#Cc2ccccc2)cc1.Oc1ccccc1>>O=C(c1ccc(C#Cc2ccccc2)cc1)c1ccc(Oc2ccccc2)cc1,,CC(=O)N(C)C,,Cc1ccccc1,,test
US06518257B1,CC(C)C(O)(c1ccc(-c2ccc(F)cc2)cc1)c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1>>CC(C)C(O)(c1ccc(-c2ccc(F)cc2)cc1)c1c[nH]cn1,,CO,,Cl,c1ccncc1,test
US05707991,CC(C)(C)OC(=O)C1CC(S(=O)(=O)c2ccccc2)C(c2ccccc2F)N1C(=O)CNC(=O)Nc1cccc(C(=O)OCc2ccccc2)c1>>CC(C)(C)OC(=O)[C@@H]1C[C@@H](Cc2ccccc2)[C@H](c2ccccc2)N1C(=O)CNC(=O)Nc1cccc(C(=O)O)c1,[Pd],CCO,,,,test
US04963553,COc1cccc(CN2CCNCC2)c1.N#Cc1cnn2c1N(C(=O)CCl)CC=C2c1ccccc1>>COc1cccc(CN2CCN(CC(=O)N3CC=C(c4ccccc4)n4ncc(C#N)c43)CC2)c1,,Cc1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20130029971A1,O=C(Nc1cc(Cl)ccc1N1CCC(CCBr)CC1)c1cccc(Cl)c1.OC1CCNCC1>>O=C(Nc1cc(Cl)ccc1N1CCC(CCN2CCC(O)CC2)CC1)c1cccc(Cl)c1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20150336935A1,C[C@@H]1[C@H](N/C(=N/C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)C[C@H]2C(C)(C)CCC[C@]2(C)[C@H]1C(=O)c1cc(O)cc(O)c1>>C[C@@H]1[C@H](NC(=N)N)C[C@H]2C(C)(C)CCC[C@]2(C)[C@H]1C(=O)c1cc(O)cc(O)c1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20110251178A1,ClI.Fc1ccc(-c2cc3n(n2)CCCC3)cc1>>Fc1ccc(-c2nn3c(c2I)CCCC3)cc1,,ClCCl,,O,,test
US20160222022A1,COC(=O)c1ccc2c(c1)OC[C@H](c1ccccc1)NC2.O=C(O)C1CCOCC1>>COC(=O)c1ccc2c(c1)OC[C@H](c1ccccc1)N(C(=O)C1CCOCC1)C2,,CN(C)C=O,,COc1nc(OC)nc([N+]2(C)CCOCC2)n1.[Cl-],,test
US20160200725A1,CNc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)c(=O)n(CCN3CCN(C(=O)OC(C)(C)C)CC3)c2n1>>CNc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)c(=O)n(CCN3CCNCC3)c2n1,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20050080256A1,COC(=S)CC(c1ccccc1)c1ccccc1.N>>NC(=S)CC(c1ccccc1)c1ccccc1,,O,,CO,,test
US20060160879A1,CCOC(=O)c1c([N+](=O)[O-])c2ccc(Br)cc2n1Cc1cccc(Cl)c1>>CCOC(=O)c1c(N)c2ccc(Br)cc2n1Cc1cccc(Cl)c1,[Fe],CC(C)O,,[Cl-].[NH4+],,test
US20030092740A1,COC(=O)C1CCCN1C(=O)c1ccc([N+](=O)[O-])cc1>>COC(=O)C1CCCN1C(=O)c1ccc(N)cc1,[Pd],CO,,,,test
US20080269208A1,Cc1cc(F)ccc1-c1cc(Cl)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1.O=C1NCCN2CCNCC12>>Cc1cc(F)ccc1-c1cc(N2CCN3CCNC(=O)C3C2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,CS(C)=O,ClCCl,O=C([O-])[O-].[K+].[K+],,test
US20090324581A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)c1ccc2[nH]ccc2c1>>COC(=O)c1ccc2c(ccn2C(=O)OC(C)(C)C)c1,CN(C)c1ccncc1,C1CCOC1,,,,test
US04225609,CS(=O)(=O)N=C=O.O=C(O)c1ccc(CCCC2SCC(=O)N2CCC2(O)CCCCC2)cc1>>CS(=O)(=O)NC(=O)c1ccc(CCCC2SCC(=O)N2CCC2(O)CCCCC2)cc1,,CC#N,,CCN(CC)CC,,test
US20140296246A1,CCOC(C)=O.Cc1noc(C)c1-c1cc(-c2cc(N)cnc2C2CC2)c2[nH]c(=O)[nH]c2c1>>CC(=O)Nc1cnc(C2CC2)c(-c2cc(-c3c(C)noc3C)cc3[nH]c(=O)[nH]c23)c1,,CC#N,CCOC(C)=O,CC(C)(C)ON=O,,test
US06211234B1,COC(=O)CCC(C(=O)c1cccc(O)c1)c1ccccc1C.ClCc1ccc(Cl)cc1>>COC(=O)CCC(C(=O)c1cccc(OCc2ccc(Cl)cc2)c1)c1ccccc1C,,CN(C)C=O,,[H-].[Na+],,test
US20030078249A1,CC(C)(C)OC(=O)N1CCC[C@H]1CO.CCOC(=O)c1ccc(O)cc1>>CCOC(=O)c1ccc(OC[C@@H]2CCCN2C(=O)OC(C)(C)C)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20100286123A1,Cc1cccc(F)c1C#N.O=C1CCC(=O)N1Br>>Cc1c(Br)ccc(F)c1C#N,,O=S(=O)(O)O,,,,test
US20150353477A1,C[C@H](N)NC(=O)c1ccc(/C=C/C(c2cc(Cl)c(Cl)c(Cl)c2)C(F)(F)F)cc1C(F)(F)F.O=C(Cl)CC(F)(F)F>>C[C@H](NC(=O)CC(F)(F)F)NC(=O)c1ccc(/C=C/C(c2cc(Cl)c(Cl)c(Cl)c2)C(F)(F)F)cc1C(F)(F)F,,ClCCCl,,CN1CCOCC1,Cl,test
US03931195,CC(=Cc1ccccn1)c1ccccc1[N+](=O)[O-]>>CC(Cc1ccccc1N)c1ccccn1,[Pd],,,CCO,,test
US04612317,CI.C[C@H]1N[C@@H](CO)Cc2c1[nH]c1ccccc21.S=C=S>>CSC(=S)N1[C@@H](CO)Cc2c([nH]c3ccccc23)[C@H]1C,,CCO,CO,CCN(CC)CC,,test
US20150011527A1,CCCCCCCOc1ccc(-c2cnc(-c3ccc(C[C@H](NC(=O)OCc4ccccc4)C(=O)N4CC(C(=O)OC)C4)cc3)nc2)cc1>>CCCCCCCOc1ccc(-c2cnc(-c3ccc(C[C@H](N)C(=O)N4CC(C(=O)OC)C4)cc3)nc2)cc1,[Pd],CO,,,,test
US20110112151A1,Cn1ccnc1S.O=C(CBr)C1(c2ccc(Cl)cc2)CCC1>>Cn1ccnc1SCC(=O)C1(c2ccc(Cl)cc2)CCC1,,CC#N,,CCN(CC)CC,,test
US20120178756A1,CC(C)(C)OC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1.CCC(=O)Cl>>CCC(=O)N1CC=C(B2OC(C)(C)C(C)(C)O2)CC1,,ClCCl,,CCN(CC)CC,O=C(O)C(F)(F)F,test
US20110077235A1,CC(C)(O)c1ccc(C(=O)Nc2cc(Cl)n3nc(C4CC4)cc3n2)cc1.OC1CCNCC1>>CC(C)(O)c1ccc(C(=O)Nc2cc(N3CCC(O)CC3)n3nc(C4CC4)cc3n2)cc1,,CN(C)C=O,,CN1CCCC1=O,,test
US20090275606A1,NOCC1CC1.O=C(O)c1c(Nc2ccc(I)cc2F)c(F)c(=O)n2c1CCC2>>O=C(NOCC1CC1)c1c(Nc2ccc(I)cc2F)c(F)c(=O)n2c1CCC2,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US20100120739A1,NNc1ccc(Cl)nn1.O=C(Cl)Cc1c(F)cc2ncccc2c1F>>O=C(Cc1c(F)cc2ncccc2c1F)NNc1ccc(Cl)nn1,,CN(C)C=O,,CCN(CC)CC,,test
US20160272617A1,Cc1cc(C(=O)NC(C)C)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)O)cc1.Nc1ccc2nc[nH]c2c1>>Cc1cc(C(=O)NC(C)C)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc3nc[nH]c3c2)cc1,,CCOC(C)=O,CS(C)=O,CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1,CCN(C(C)C)C(C)C,test
US20110046171A1,NS(=O)(=O)c1ccc([N+](=O)[O-])c(F)c1>>Nc1ccc(S(N)(=O)=O)cc1F,[Pd],CO,,,,test
US05147886,CS.O=C(CBr)c1ccc(C(F)(F)F)cc1>>CSCC(=O)c1ccc(C(F)(F)F)cc1,,CO,,O,[Na],test
US20060217371A1,CCOC(=O)C1=C(c2cccc(CCO)c2)CC2CN(C(C)=O)CC1N2C(=O)OC(C)(C)C(Cl)(Cl)Cl>>CC(=O)N1CC2CC(c3cccc(CCO)c3)=C(C(=O)O)C(C1)N2C(=O)OC(C)(C)C(Cl)(Cl)Cl,,CCO,,Cl,[Na+].[OH-],test
US20060084643A1,CCCCC(=O)Cl.NC1C(=O)Nc2ccccc2NC1=O>>CCCCC(=O)NC1C(=O)Nc2ccccc2NC1=O,,CN(C)C=O,,CCN(CC)CC,,test
US20150307451A1,COC(=O)c1cc(Cc2ccc(F)c(OC)c2)c(C)c(C)c1O.O=S(=O)(N(c1ccccc1)S(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1cc(Cc2ccc(F)c(OC)c2)c(C)c(C)c1OS(=O)(=O)C(F)(F)F,,CCOC(C)=O,CN(C)C=O,[H-].[Na+],,test
US20120220616A1,CC(C)(C)[Si](C)(C)Cl.COc1cc(CBr)sc1CO>>COc1cc(CBr)sc1CO[Si](C)(C)C(C)(C)C,,ClCCl,,c1c[nH]cn1,,test
US20150158858A1,COC(=O)c1cccc(C=O)n1.Nc1ccccc1>>COC(=O)c1cccc(CNc2ccccc2)n1,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US05668291,Cc1ccc(C(=O)NC(CC(C)C)C(=O)OC(C)(C)C)c(SSc2cc(C)ccc2C(=O)NC(CC(C)C)C(=O)OC(C)(C)C)c1>>Cc1ccc(C(=O)NC(CC(C)C)C(=O)O)c(SSc2cc(C)ccc2C(=O)NC(CC(C)C)C(=O)O)c1,,ClCCl,,COc1ccccc1,O=C(O)C(F)(F)F,test
US20130190322A1,CN1CCc2[nH]c3ccc(Cl)cc3c2C1.COc1ccc(C(C)=CBr)cn1>>COc1ccc(/C(C)=C/n2c3c(c4cc(Cl)ccc42)CN(C)CC3)cn1,[Cu]I,CN(C)C=O,,O=C(O)[C@@H]1CCCN1,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20150158858A1,COC(=O)Cc1cccs1.COC(Cl)Cl.O>>COC(=O)Cc1ccc(C=O)s1,,ClCCl,O,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20110257151A1,CN1CCN(c2cccc(C3Nc4ccc(C(=O)O)cc4CC3(C)C)c2)C(=O)C1=O.NS(=O)(=O)C1CC1>>CN1CCN(c2cccc(C3Nc4ccc(C(=O)NS(=O)(=O)C5CC5)cc4CC3(C)C)c2)C(=O)C1=O,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,[H-].[Na+],test
US20070213341A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccc(F)cc1C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12>>Cc1ccc(F)cc1C1NC(=O)CC(c2cccc(Cl)c2)C12C(=O)N(C(=O)OC(C)(C)C)c1cc(Cl)ccc12,CN(C)c1ccncc1,ClCCl,,,,test
US20120302610A1,CCOC(=O)CCNC(=O)c1ccc(-c2ccc(Cl)cc2CNc2ccc(-c3ccc(Cl)cc3)cc2)cn1>>O=C(O)CCNC(=O)c1ccc(-c2ccc(Cl)cc2CNc2ccc(-c3ccc(Cl)cc3)cc2)cn1,,CO,,C1CCOC1,[Na+].[OH-],test
US05061719,CCCCCCC1(C)OC(C)(C)CN1C(=O)Cl.c1c[nH]cn1>>CCCCCCC1(C)OC(C)(C)CN1C(=O)n1ccnc1,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150119385A1,COC(OC)c1nc2c(cc1I)CCCN2.O=C(Oc1ccccc1)Oc1ccccc1>>COC(OC)c1nc2c(cc1I)CCCN2C(=O)Oc1ccccc1,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US05981537,Nc1cc(Cl)nc(Cl)n1.OCc1cccc2ccccc12>>Nc1cc(Cl)nc(OCc2cccc3ccccc23)n1,,C1CCOC1,,[H-].[Na+],,test
US20130211075A1,Cc1c(C(=O)Nc2ccc(C3(C#N)CCNCC3)nc2)cnn1-c1ccc(C(F)(F)F)cn1.O=C1COC1>>Cc1c(C(=O)Nc2ccc(C3(C#N)CCN(C4COC4)CC3)nc2)cnn1-c1ccc(C(F)(F)F)cn1,,C1CCOC1,ClCCl,O=C([O-])O.[Na+],,test
US20130203776A1,CS(=O)(=O)Cl.Fc1ccc2c(c1)[C@H]1CCCN1c1ccn3ncc(c3n1)CNCCCO2>>CS(=O)(=O)N1CCCOc2ccc(F)cc2[C@H]2CCCN2c2ccn3ncc(c3n2)C1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20050187243A1,CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(=O)[O-])CC1)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1>>CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(=O)O)CC1)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1,,O,,Cl,,test
US04452851,CCC1=C(C(=S)OC(c2ccccc2)c2ccccc2)N2C(=O)C(NC(=O)C(=NOCC(=O)OC(C)(C)C)c3ccccc3)[C@H]2SC1>>CCC1=C(C(O)=S)N2C(=O)C(NC(=O)C(=NOCC(=O)O)c3ccccc3)[C@H]2SC1,,O=C(O)C(F)(F)F,,COc1ccccc1,,test
US20120172411A1,CCCCC/C=C\C/C=C\CCCCCCCCC(CCCCCCCC/C=C\C/C=C\CCCCC)OC(=O)Cl.CCCCC/C=C\C/C=C\CCCCCCCCNCCCN(C)C>>CCCCC/C=C\C/C=C\CCCCCCCCC(CCCCCCCC/C=C\C/C=C\CCCCC)OC(=O)N(CCCCCCCC/C=C\C/C=C\CCCCC)CCCN(C)C,,ClCCl,,CCN(CC)CC,,test
US20160115158A1,COc1cc(Cl)cnc1NS(=O)(=O)c1cncc(-c2ccccc2)c1>>O=S(=O)(Nc1ncc(Cl)cc1O)c1cncc(-c2ccccc2)c1,,ClCCl,,BrB(Br)Br,O=C([O-])O.[Na+],test
US20100222319A1,CCNc1nc(Cl)ccc1C(=O)O.NCCN1CCCCC1>>CCNc1nc(Cl)ccc1C(=O)NCCN1CCCCC1,,C1CCOC1,,CCN(CC)CC,CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C.F[P-](F)(F)(F)(F)F,test
US20140329799A1,CC(C)(C)OC(=O)N1CCC[C@@H](Nc2nc(C3CCNCC3)[nH]c(=O)c2-c2nc3ccccc3s2)C1.Fc1ccccn1>>CC(C)(C)OC(=O)N1CCC[C@@H](Nc2nc(C3CCN(c4ccccn4)CC3)[nH]c(=O)c2-c2nc3ccccc3s2)C1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20130331350A1,O=C(O)COCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21.O=C1CCC(=O)N1O>>O=C(COCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21)ON1C(=O)CCC1=O,,C1CCOC1,,CC(C)N=C=NC(C)C,,test
US20060293310A1,CC(C)(C)OC(=O)N1CCN(c2ccc(Br)nc2)CC1>>Brc1ccc(N2CCNCC2)cn1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100137321A1,CCOC(=O)c1cnc(N)nc1O.O=C(CBr)c1ccc(F)cc1>>CCOC(=O)c1cn2cc(-c3ccc(F)cc3)nc2nc1O,,C1COCCO1,,CCN(C(C)C)C(C)C,,test
US20120264737A1,C1CNC1.CCc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2F)[nH]1>>CCc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2N2CCC2)[nH]1,,C1COCCO1,,Cl,O=C([O-])[O-].[K+].[K+],test
US20130217664A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCc1cc(C#N)ccc1N(C)c1cc2c(cn1)ncn2C>>CCc1cc(CNC(=O)OC(C)(C)C)ccc1N(C)c1cc2c(cn1)ncn2C,,CO,,[BH4-].[Na+],,test
US20070232583A1,O=S(=O)(Cl)c1cccc(-c2cccc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)(F)F)n3)c2)c1.OCCNCCO>>O=S(=O)(c1cccc(-c2cccc(-c3nc(-c4ccc(C(F)(F)F)cc4)cc(C(F)(F)F)n3)c2)c1)N(CCO)CCO,,C1CCOC1,,CCN(CC)CC,,test
US20060069140A1,CC(=O)c1c(C)nn(-c2ccc(C(F)(F)F)cn2)c1O.COC(=O)c1ccc(C(=O)NN)cc1>>COC(=O)c1ccc(C(=O)NN=C(C)c2c(C)nn(-c3ccc(C(F)(F)F)cn3)c2O)cc1,,CN(C)C=O,,,,test
US20140121197A1,Clc1c(-c2ccccc2)nnc2[nH]ncc12.O=C1CCC(=O)N1I>>Clc1c(-c2ccccc2)nnc2[nH]nc(I)c12,,CC#N,,,,test
US20080045537A1,CN(Cc1nc2c(C(=O)Oc3c(F)c(F)c(F)c(F)c3F)cccc2[nH]1)C1CCCc2cccnc21.CN1CCN(CCCN)CC1>>CN1CCN(CCCNC(=O)c2cccc3[nH]c(CN(C)C4CCCc5cccnc54)nc23)CC1,,CN(C)C=O,,,,test
US20120149737A1,CCOc1c(Cl)cc(C(=O)Nc2ccc(C(=O)OC)c(C)c2)cc1Cl>>CCOc1c(Cl)cc(C(=O)Nc2ccc(C(=O)O)c(C)c2)cc1Cl,,C1CCOC1,O,[Li+].[OH-],,test
US20150232444A1,C#CCOc1ccc(C(=O)OC)cc1N=[N+]=[N-]>>C#CCOc1ccc(CO)cc1N=[N+]=[N-],,ClCCl,,CC(C)C[AlH]CC(C)C,,test
US04009170,CC(C=O)=Cc1ccccc1.COc1cc2c(cc1OC)C(NN)=NCC2>>COc1cc2c(cc1OC)C(NN=CC(C)=Cc1ccccc1)=NCC2,,CCO,O,CO,Cl,test
US20070054907A1,CCCCCCCc1nnc(Sc2ccc(CNc3ccc(CC(=O)OCC)cc3)c(OCCC)c2)n1C>>CCCCCCCc1nnc(Sc2ccc(CNc3ccc(CC(=O)O)cc3)c(OCCC)c2)n1C,,CO,,Cl,O=C([O-])[O-].[K+].[K+],test
US20040019098A1,C1CCNC1.CS(=O)(=O)OCCC1OC(=C2C(=O)Nc3ccccc32)c2ccccc21>>O=C1Nc2ccccc2C1=C1OC(CCN2CCCC2)c2ccccc21,,C1COCCO1,,,,test
US20060025474A1,BrC(Br)(Br)Br.CCC(CC)(c1ccc(CCO)c(C)c1)c1ccc(OC[C@@H]2COC(C)(C)O2)c(C)c1>>CCC(CC)(c1ccc(CCBr)c(C)c1)c1ccc(OC[C@@H]2COC(C)(C)O2)c(C)c1,,ClCCl,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20020132796A1,CC1(C)CCC(n2ccnc2)c2ccc(C#Cc3ccc(C(=O)[O-])cc3)cc21.CCO>>CC1(C)CCC(n2ccnc2)c2ccc(C#Cc3ccc(CC(=O)O)cc3)cc21,,C1CCOC1,,[Na+].[OH-],,test
US20120034660A1,CCOC(=O)C(NC(=O)OCc1ccccc1)C(=O)OCC.COC(=O)CBr>>CCOC(=O)C(CC(=O)OC)(NC(=O)OCc1ccccc1)C(=O)OCC,,CN(C)C=O,,Cl,[I-].[K+],test
US04426382,C1CCOC1.COc1cc2nc(N3CCNCC3)nc(N)c2cc1OC.O=C(Cl)C=C1CCCCC1>>COc1cc2nc(N3CCN(C(=O)C=C4CCCCC4)CC3)nc(N)c2cc1OC.Cl.O,,CCN(CC)CC,,,,test
US20040073025A1,COc1ccc(CN)cc1.O=Cc1cc(Cl)ccc1-c1cnsn1>>COc1ccc(CNCc2cc(Cl)ccc2-c2cnsn2)cc1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20090291988A1,CC(C(N)=O)c1ccc(Br)cc1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C>>CC(C(N)=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1,,CN(C)C=O,,CC(=O)[O-].[K+],,test
US20100210647A1,Nc1cccc2cc(C3=NCCS3)[nH]c12.O=C1CCCC1>>c1cc(NC2CCCC2)c2[nH]c(C3=NCCS3)cc2c1,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150232463A1,Cc1nc(C)c([C@H](OC(C)(C)C)C(=O)OC(C)C)c(N2CCC(C)CC2)c1-c1ccc(OCCc2ccc(F)cc2)cc1>>Cc1nc(C)c([C@H](OC(C)(C)C)C(=O)O)c(N2CCC(C)CC2)c1-c1ccc(OCCc2ccc(F)cc2)cc1,,CCO,,Cl,[Na+].[OH-],test
US20140213615A1,C1CCOC1.CON(C)C(=O)C(C)C.ClCCl.[Li]C(C)CC>>COc1ccc2[nH]c(CC(C)C)cc2c1,,ClCCl,ClCCl,O=C(O)C(F)(F)F,,test
US20050277652A1,C1COCCN1.O=C(Nc1cc(Oc2ccc([N+](=O)[O-])cc2Cl)ccn1)Oc1ccccc1>>Nc1ccc(Oc2ccnc(NC(=O)N3CCOCC3)c2)c(Cl)c1,,C1CCOC1,,,,test
US20140213571A1,BrCBr.Oc1ccc(Cl)cc1-c1nc2ccccc2[nH]1>>Clc1ccc2c(c1)-c1nc3ccccc3n1CO2,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20040052822A1,N#CCC(=O)C1CCN(c2ccccc2)CC1.Nc1cc[nH]n1.O=Cc1cccc2nonc12>>N#CC1=C(C2CCN(c3ccccc3)CC2)Nc2n[nH]cc2C1c1cccc2nonc12,,CC#N,,,,test
US04014869,C=C(C)C.O=C(O)C(=O)c1ccco1>>CC(C)(C)OC(=O)C(=O)c1ccco1,,CCOCC,,O=S(=O)(O)O,,test
US20130078570A1,C=CCBr.[N-]=[N+]=NS(=O)(=O)c1ccc(O)cc1>>C=CCOc1ccc(S(=O)(=O)N=[N+]=[N-])cc1,,CN(C)C=O,,O,[Na+].[OH-],test
US20110245353A1,N#Cc1c(OC2CCCCC2)cccc1[N+](=O)[O-]>>N#Cc1c(N)cccc1OC1CCCCC1,[Fe],C1CCOC1,CC(=O)O,CCOC(C)=O,,test
US20090099200A1,NC(=O)c1cnc(N2CCNCC2)s1.O=C(Cl)c1cc(F)ccc1C(F)(F)F>>NC(=O)c1cnc(N2CCN(C(=O)c3cc(F)ccc3C(F)(F)F)CC2)s1,,CN(C)C=O,,CCN(CC)CC,,test
US04713396,Nc1cc(Cl)cc(C(F)(F)F)c1Cl.O=c1nc(-c2c(F)cccc2F)ss1>>O=C(NC(=S)c1c(F)cccc1F)Nc1cc(Cl)cc(C(F)(F)F)c1Cl,,ClCCl,,CCCCP(CCCC)CCCC,,test
US20090023731A1,Nc1ccc(OCCCN2CCOCC2)cc1.O=C=Nc1ccccc1>>O=C(Nc1ccccc1)Nc1ccc(OCCCN2CCOCC2)cc1,,ClCCl,,,,test
US20060252797A1,BrCC1CC1.CC(=O)N(c1ccccc1)C1(c2nc(C)cs2)CCNCC1>>CC(=O)N(c1ccccc1)C1(c2nc(C)cs2)CCN(CC2CC2)CC1,,CN(C)C=O,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20150344466A1,CCCCn1cc(C(=O)OCC)nn1>>CCCCn1cc(C(=O)O)nn1,,O,,CCO,[K+].[OH-],test
US20090176775A1,O=C(Cl)Oc1ccc([N+](=O)[O-])cc1.c1ccc2c(c1)NCCO2>>O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCOc2ccccc21,,C1CCOC1,,CCN(CC)CC,,test
US20090023724A1,O=c1[nH]c2ncc(-c3ccc(-c4n[nH]c(CCl)n4)cc3)nc2n1CCC1CCOCC1.O=c1[nH]c2ncc(-c3ccc(-c4n[nH]c(CO)n4)cc3)nc2n1CCC1CCOCC1>>NCc1nc(-c2ccc(-c3cnc4[nH]c(=O)n(CCC5CCOCC5)c4n3)cc2)n[nH]1,,O=S(Cl)Cl,,,,test
US20060173021A1,O=C(Nc1cnc(Br)cn1)c1c(F)cccc1F.OB(O)c1cc(C(F)(F)F)ccc1Cl>>O=C(Nc1cnc(-c2cc(C(F)(F)F)ccc2Cl)cn1)c1c(F)cccc1F,[Pd],C1COCCO1,,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20090042900A1,O=C(O)[C@@H]1CC[C@@H](C(=O)c2cccc(Cl)c2)CC1>>O=C(O)C1CCC(Cc2cccc(Cl)c2)CC1,[Zn],O=CO,,Cl,,test
US20090163512A1,Cc1ccc(F)cc1C1N(c2cc(Cl)ccc2OCS(=O)(=O)NC(C)(C)C)C(=O)CCC12C(=O)N(C(=O)OC(C)(C)C)c1cc(Cl)ccc12>>Cc1ccc(F)cc1C1N(c2cc(Cl)ccc2OCS(=O)(=O)NC(C)(C)C)C(=O)CCC12C(=O)Nc1cc(Cl)ccc12,,ClCCl,,O=C(O)C(F)(F)F,,test
US20160257682A1,NN.O=Cc1cnc(Br)cc1Cl>>Brc1cc2[nH]ncc2cn1,,C1COCCO1,,CCN(CC)CC,O,test
US20110152247A1,O=C1CSC(=O)N1.O=Cc1ccc2c(c1)CN(c1nc3ccccc3o1)CCO2>>O=C1NC(=O)C(=Cc2ccc3c(c2)CN(c2nc4ccccc4o2)CCO3)S1,,Cc1ccccc1,,C1CC[NH2+]CC1.CC(=O)[O-],,test
US20130065906A1,CC(C)(C)OC(=O)N1CCC(NC2CC2)CC1.Cc1ncoc1-c1ccc(C(=O)Cl)cc1>>Cc1ncoc1-c1ccc(C(=O)N(C2CC2)C2CCN(C(=O)OC(C)(C)C)CC2)cc1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US05051434,CSC(N)=N[N+](=O)[O-].ClCc1ccc(Cl)nc1>>CSC(=N[N+](=O)[O-])NCc1ccc(Cl)nc1,,CS(C)=O,,[H-].[Na+],,test
US20050124656A1,CCCCCCCCCCCC(=N)NO.O=Cc1ccc(C(=O)O)cc1>>CCCCCCCCCCCc1noc(-c2ccc(C=O)cc2)n1,,ClCCl,,CC(C)N=C=NC(C)C,,test
US20090143440A1,Cc1cc(Cl)[nH]n1.O=[Mn](=O)(=O)[O-]>>O=C(O)c1cc(Cl)[nH]n1,,CC(C)(C)O,,O,,test
US20150210666A1,CC#CCOc1ccc(C[C@H](NC(=O)[C@@H](/C=C/CCCCCCC(=O)CCCCCCC)[C@@](O)(CC(=O)O)C(=O)O)C(=O)OC)cc1>>CC#CCOc1ccc(C[C@H](NC(=O)[C@@H](/C=C/CCCCCCC(O)CCCCCCC)[C@@](O)(CC(=O)O)C(=O)O)C(=O)OC)cc1,,CO,,[BH4-].[Na+],,test
US20140275087A1,Cn1cnc(S(=O)(=O)N2C[C@@H](C(=O)O)[C@H](c3ccc(F)cc3)C2)c1.Nc1ccccc1>>Cn1cnc(S(=O)(=O)N2C[C@@H](C(=O)Nc3ccccc3)[C@H](c3ccc(F)cc3)C2)c1,,CN(C)C=O,c1ccncc1,CCN=C=NCCCN(C)C,Cl,test
US20120258950A1,CC(Br)C(N)=O.O=C(Cc1ccc(Cl)cc1)Nc1cncc(C(=O)c2c[nH]c3ncncc23)c1>>CC(C(N)=O)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(Cl)cc3)c2)c2cncnc21,,CN(C)C=O,,O,O=C([O-])[O-].[Cs+].[Cs+],test
US20090215818A1,OCc1ccc2ncc(Br)n2c1>>O=Cc1ccc2ncc(Br)n2c1,O=[Mn]=O,ClC(Cl)Cl,,,,test
US05624939,CC(C)C[C@H]1CC[C@@H](C(=O)OC(C)(C)C)N1C(=O)CNC(=O)Nc1cccc(C(=O)OCc2ccccc2)c1>>O=C(O)c1ccccc1,[Pd],CCO,,,,test
US09079897B2,Nc1ccnc(Cl)c1.O=[N+]([O-])c1ccc(Br)nc1Br>>O=[N+]([O-])c1ccc(Br)nc1Nc1ccnc(Cl)c1,,CC(C)O,,CCN(CC)CC,,test
US05096919,CC(=O)CCC(C)=O.Nc1ccc(O)cc1>>Cc1ccc(C)n1-c1ccc(O)cc1,,Cc1ccccc1,,O,,test
US20030166923A1,CC(=O)c1cc(C)n(CCO[Si](C)(C)C(C)(C)C)n1>>CC(=O)c1cc(C)n(CCO)n1,,CO,,Cl,,test
US20100311790A1,CC#CCBr.O=C(NCc1cccc(O)c1F)c1ccc2ncccc2c1>>CC#CCOc1cccc(CNC(=O)c2ccc3ncccc3c2)c1F,,O,,CN(C)C=O,O=C([O-])[O-].[K+].[K+],test
US20150018343A1,Cc1nc2c3c(nn2cc1Cl)CN(C(=O)c1ccc(F)cc1OCCN(C)C(=O)OC(C)(C)C)C3.Cl>>CNCCOc1cc(F)ccc1C(=O)N1Cc2nn3cc(Cl)c(C)nc3c2C1.Cl,,ClCCl,,C1COCCO1,,test
US03940411,Cn1c([N+](=O)[O-])cnc1C(=N)NNC(N)=S>>Cn1c([N+](=O)[O-])cnc1-c1nnc(N)s1,,O,,Cl,,test
US20070004736A1,ClC(c1ccccc1)(c1ccccc1)c1ccccc1.O=C(CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCC(c2c[nH]cn2)CC1>>O=C(CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCC(c2cn(C(c3ccccc3)(c3ccccc3)c3ccccc3)cn2)CC1,,CN(C)C=O,,CCN(CC)CC,,test
US20090105266A1,COC(=O)c1cnc(Nc2ccc(C)nc2)c(Cl)c1>>Cc1ccc(Nc2ncc(C(=O)O)cc2Cl)cn1,,CO,,Cl,[Na+].[OH-],test
US05439910,CC(=O)c1nccc(OCC(F)(F)F)n1.NO>>CC(=NO)c1nccc(OCC(F)(F)F)n1,,CCO,O,Cl,CC(=O)[O-].[Na+],test
US20110311461A1,O=C(O)C(Nc1ccccc1)c1cc2ccccc2s1.O[C@H]1CN2CCC1CC2>>O=C(O[C@H]1CN2CCC1CC2)C(Nc1ccccc1)c1cc2ccccc2s1,,C1CCOC1,,C(=NC1CCCCC1)=NC1CCCCC1,On1nnc2ccccc21,test
US20130137699A1,O=[N+]([O-])c1cnc(Cl)nc1.OB(O)c1ccc(OCc2ccccc2)c(C23CC4CC(CC(C4)C2)C3)c1>>O=[N+]([O-])c1cnc(-c2ccc(OCc3ccccc3)c(C34CC5CC(CC(C5)C3)C4)c2)nc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,O=C([O-])O.[Na+],,test
US20100120761A1,NCC(F)(F)F.O=C=Nc1cccc(Br)c1>>O=C(NCC(F)(F)F)Nc1cccc(Br)c1,,C1CCOC1,,,,test
US20070249670A1,COC(=O)[C@@H](NC(=O)c1ccc(-c2cccc(F)c2)cc1N)C1CCCCC1.Cc1cc(C)c(N=C=O)c(C)c1>>COC(=O)[C@@H](NC(=O)c1ccc(-c2cccc(F)c2)cc1NC(=O)Nc1c(C)cc(C)cc1C)C1CCCCC1,,c1ccncc1,,CCCCCC,CCOC(C)=O,test
US20030186983A1,C1CNCCN1.O=C(O)C1CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5cccc(F)c5)c4)c23)CC1>>O=C(C1CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5cccc(F)c5)c4)c23)CC1)N1CCNCC1,CN(C)c1ccncc1,ClCCl,,ClCCCl,,test
US20120196884A1,Cc1nn(-c2ccc(F)cc2)c(C)c1S(=O)(=O)Nc1ccc(NC(=O)Nc2ccccc2)cc1.OCCCOCc1ccccc1>>Cc1nn(-c2ccc(F)cc2)c(C)c1S(=O)(=O)N(CCCOCc1ccccc1)c1ccc(NC(=O)Nc2ccccc2)cc1,,C1CCOC1,,CCOC(=O)N=NC(=O)OCC,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20070173508A1,N#CC1(c2cccc(Sc3ccc4c(Cl)cc(N=C(c5ccccc5)c5ccccc5)nc4c3)c2)CCOCC1.OB(O)c1ccccc1>>N#CC1(c2cccc(Sc3ccc4c(-c5ccccc5)cc(N=C(c5ccccc5)c5ccccc5)nc4c3)c2)CCOCC1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,C1COCCO1,,O=C([O-])[O-].[K+].[K+],,test
US20110195127A1,CCCCC/C=C\C/C=C\CCCCCCCCC(=O)CCCCCCCC/C=C\C/C=C\CCCCC.OCCC(O)CO>>CCCCC/C=C\C/C=C\CCCCCCCCC1(CCCCCCCC/C=C\C/C=C\CCCCC)OCC(CCO)O1,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)[O-])cc1.c1cc[nH+]cc1,,test
US08507672B2,C[C@H]1CNCCN1C(=O)OC(C)(C)C.Cc1c[nH]c2ncnc(Cl)c12>>Cc1c[nH]c2ncnc(N3CCN(C(=O)OC(C)(C)C)[C@@H](C)C3)c12,,CC(C)O,,CCN(C(C)C)C(C)C,,test
US20130190330A1,C=O.O=c1[nH]nc(-c2ccc(Cl)cc2)n1C1CC1>>O=c1n(CO)nc(-c2ccc(Cl)cc2)n1C1CC1,,O,,,,test
US20110098324A1,CC(C)N.CCOC(=O)CNC(=O)c1c(O)c(C(=O)OC)c(O)n(Cc2ccccc2Cl)c1=O>>CC(C)NC(=O)c1c(O)c(C(=O)NCC(=O)O)c(=O)n(Cc2ccccc2Cl)c1O,,ClC(Cl)Cl,,,,test
US20130296338A1,Cc1c(F)ccc2cc(C=O)c(Cl)nc12.OB(O)c1cccnc1>>Cc1c(F)ccc2cc(C=O)c(-c3cccnc3)nc12,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,COCCOC,O,O=C([O-])[O-].[Na+].[Na+],,test
US20160096834A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.NC1(c2ccc(Br)cc2F)CC1>>CC(C)(C)OC(=O)NC1(c2ccc(Br)cc2F)CC1,CN(C)c1ccncc1,ClCCl,O,,,test
US20130023541A1,CCNCc1ccc(CN2CCN(c3ncccc3C(=O)OC(C)C)CC2)cc1.O=CCCc1c(F)cccc1Cl>>CCN(CCCc1c(F)cccc1Cl)Cc1ccc(CN2CCN(c3ncccc3C(=O)OC(C)C)CC2)cc1,,CO,,CC(=O)O,[BH3-]C#N.[Na+],test
US20070155839A1,C=CC(=O)OCC.Oc1ccc(C(=C2CCCCCC2)c2ccc(Br)cc2)cc1Cl>>CCOC(=O)/C=C/c1ccc(C(=C2CCCCCC2)c2ccc(O)c(Cl)c2)cc1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,CCOC(C)=O,O,CCN(CC)CC,CN(C)C=O,test
US20110312965A1,CC(C)(C)OC(=O)/C=C/c1ccc(-c2ccc(OCN3C(=O)c4ccccc4C3=O)c(C34CC5CC(CC(C5)C3)C4)c2)cc1>>O=C(O)/C=C/c1ccc(-c2ccc(OCN3C(=O)c4ccccc4C3=O)c(C34CC5CC(CC(C5)C3)C4)c2)cc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20020049322A1,COc1cc(Br)c(C#N)c([N+](=O)[O-])c1.OB(O)c1ccccc1Cl>>COc1cc(-c2ccccc2Cl)c(C#N)c([N+](=O)[O-])c1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,Cc1ccccc1,,CCO,O=C([O-])[O-].[Na+].[Na+],test
US20140038926A1,F[C@@H]1CCNC1.O=C(c1nccs1)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(Cl)nc1)C2>>O=C(c1nccs1)[C@]12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(N3CC[C@@H](F)C3)nc1)C2,,CN(C)C=O,,Cl,,test
US20150189880A1,CCS(=O)(=O)c1cccnc1C(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1.CI>>CCS(=O)(=O)c1cccnc1C(=O)N(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1,,CN(C)C=O,O,CC(C)=O,O=C([O-])[O-].[K+].[K+],test
US04150032,CCOC(=O)CC1(C)C(=O)CCc2ccc(OC)cc21.CN>>COc1ccc2c(c1)C1(C)CC(=O)N(C)C1(O)CC2,,CCO,,,,test
US20130089512A1,CC1(C)OC[C@@H](CCl)O1.O=c1[nH]c2cnc(Cl)nc2n1C1CCOCC1>>CC1(C)OC[C@H](Cn2c(=O)n(C3CCOCC3)c3nc(Cl)ncc32)O1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US03962227,ClP(Cl)Cl.O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(O)CS[C@H]12>>O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(Cl)CS[C@H]12,,CCOC(C)=O,,CN(C)C=O,,test
US20120270893A1,CC(C)(C)n1ncc2c1C(=O)C(Br)C1(CCN(C(=O)OCc3ccccc3)CC1)C2>>CC(C)(C)n1ncc2c1C(=O)CC1(CCN(C(=O)OCc3ccccc3)CC1)C2,[Zn],C1CCOC1,,[Cl-].[NH4+],,test
US20160152616A1,CC(C)=CCn1c(=O)[nH]c2ccccc21>>CC1(C)CCn2c(=O)[nH]c3cccc1c32,,Clc1ccccc1,,[Al+3].[Cl-].[Cl-].[Cl-],,test
US20100009991A1,COC(=O)CCOc1cccc(CCCn2cc(C(c3ccccc3)c3ccccc3)ccc2=O)c1>>O=C(O)CCOc1cccc(CCCn2cc(C(c3ccccc3)c3ccccc3)ccc2=O)c1,,CO,,Cl,[Na+].[OH-],test
US04278748,O=[N+]([O-])c1ccc2[nH]nnc2c1>>Nc1ccc2[nH]nnc2c1,[Ni],CCO,,[H][H],,test
US20080280875A1,CC(C)(C)OC(=O)c1cc(O)c2c(c1)OC(COc1ccccc1)C2.CC(C)I>>CC(C)Oc1cc(C(=O)OC(C)(C)C)cc2c1CC(COc1ccccc1)O2,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05859240,CCCCC(N)(CC)CO>>CCCC[C@](N)(CC)CO,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20120295875A1,CC(C)Br.OB1OCc2ccc(O)cc21>>CC(C)Oc1ccc2c(c1)B(O)OC2,,CN(C)C=O,,Cl,[H-].[Na+],test
US04562256,CC#N.CCOC(=O)C1CC=CCC1>>N#CCC(=O)C1CC=CCC1,,Cc1ccccc1,,[H-].[Na+],,test
US05364867,BrCCCc1ccccc1.O=C(c1ccccc1)C1(c2ccccc2)CCNCC1>>O=C(c1ccccc1)C1(c2ccccc2)CCN(CCCc2ccccc2)CC1,,CCCCO,,O=C([O-])[O-].[Na+].[Na+],,test
US20050277643A1,CN1CCOc2cc(N)ccc21.Clc1cccnc1N1CCc2c(Cl)ncnc2C1>>CN1CCOc2cc(Nc3ncnc4c3CCN(c3ncccc3Cl)C4)ccc21,,CC#N,,[I-].[Na+],,test
US05656642,CSc1ccc(CCN(C)C2CCN(C(=O)c3ccccc3)CC2)cc1>>CSc1ccc(CCN(C)C2CCNCC2)cc1,,CCO,,Cl,,test
US20120277190A1,CC(C)(C)c1ccc2c(c1)CC[C@H]2N.Cc1ccc(S(=O)(=O)O)cc1>>CC(C)(C)c1ccc2c(c1)CC[C@H]2N.Cc1ccc(S(=O)(=O)O)cc1,,CO,,,,test
US20100016589A1,COc1cc(C(=O)N2CCN(c3ccccc3OC)CC2)c([N+](=O)[O-])cc1OCCCBr.COc1ccccc1N1CCNCC1>>COc1cc(C(=O)N2CCN(c3ccccc3OC)CC2)c([N+](=O)[O-])cc1OCCCN1CCN(c2ccccc2OC)CC1,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20140023611A1,CN(CCN1CCOCC1)C(=O)c1cccc(C(=O)O)c1.O=C(Cl)C(=O)Cl>>CN(CCN1CCOCC1)C(=O)c1cccc(C(=O)Cl)c1,CN(C)C=O,ClCCl,,,,test
US20100173886A1,CC(C)CCN.N#Cc1ccc(Oc2ccc(C=O)c3ccccc23)c(Cl)c1>>CC(C)CCNCc1ccc(Oc2ccc(C#N)cc2Cl)c2ccccc12,,ClCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US20040248951A1,CCOC(=O)c1cnc(-c2ccc(C(F)(F)F)cc2)s1>>OCc1cnc(-c2ccc(C(F)(F)F)cc2)s1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US20030166639A1,CC(C)(C)OC(=O)Nc1ccc(-n2cccc2)cc1NC(=O)CC(=O)c1cccc(-c2ccccn2)c1>>O=C1CC(c2cccc(-c3ccccn3)c2)=Nc2ccc(-n3cccc3)cc2N1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20100190766A1,FC1CCNCC1.O=Cc1ccc(C#Cc2ccc(C(=O)O)cc2)cc1>>O=C(O)c1ccc(C#Cc2ccc(CN3CCC(F)CC3)cc2)cc1,,CCO,,CC(=O)O,Cl,test
US20150232481A1,Fc1ccc(OCc2ccccc2)c(CCI)c1F.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>Fc1ccc(OCc2ccccc2)c(CC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)c1F.[I-],,Cc1ccccc1C,,,,test
US20040082571A1,CCOC(=O)c1cc(C)[nH]n1.O=C1CCC(=O)N1Cl>>CCOC(=O)c1[nH]nc(C)c1Cl,,CN(C)C=O,,,,test
US20090093454A1,O=C([O-])N1CCC[C@H](Cn2c(CN3CCC[C@H]4CCc5cccnc5[C@H]43)nc3ccccc32)C1>>c1cnc2c(c1)CC[C@@H]1CCCN(Cc3nc4ccccc4n3C[C@H]3CCCNC3)[C@H]21,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150238601A1,C1CCNC1.Clc1cc(Nc2ccc3[nH]ncc3c2)nc(Cl)n1>>Clc1cc(Nc2ccc3[nH]ncc3c2)nc(N2CCCC2)n1,,CCCCO,,CCN(C(C)C)C(C)C,,test
US20130289048A1,Cc1cc(N(C)C(=O)C2CCC(S(=O)(=O)c3ccc(Cl)cc3)CC2)ccc1CN1CCN(C(=O)OC(C)(C)C)[C@@H](C)C1>>Cc1cc(N(C)C(=O)C2CCC(S(=O)(=O)c3ccc(Cl)cc3)CC2)ccc1CN1CCN[C@@H](C)C1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20040023938A1,Cc1ccc(S(=O)(=O)Cl)cc1.Nc1ccccc1[N+](=O)[O-]>>Cc1ccc(S(=O)(=O)Nc2ccccc2[N+](=O)[O-])cc1,,c1ccncc1,,O,,test
US20060135488A1,COC(=O)c1sc2cc(C(=O)OC(C)(C)C)ccc2c1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>COC(=O)c1sc2cc(C(=O)OC(C)(C)C)ccc2c1OS(=O)(=O)C(F)(F)F,,CCN(CC)CC,ClCCl,CCOC(C)=O,O,test
US03994941,C=O.CC#N.NCCN.NCCc1nnc2n1-c1ccc(F)cc1C(c1ccccc1)=NC2>>CN(C)CCN1CN2C(=N1)CN=C(c1ccccc1)c1cc(F)ccc12,,CC#N,,CC(=O)O,[BH3-]C#N.[Na+],test
US20090239810A1,CCOC(=O)c1cc(-c2ccccc2OCc2ccccc2)n(C)n1>>CCOC(=O)c1cc(-c2ccccc2O)n(C)n1,[Pd],CO,,,,test
US20040082784A1,CCOC(=O)C(C)=O.CC[C@H](COC)Nc1ncnc(-c2cc(C)c(OC)cc2C)c1N>>CC[C@H](COC)n1c(=O)c(C)nc2c(-c3cc(C)c(OC)cc3C)ncnc21,,CCO,,,,test
US20070004758A1,C=C[C@H]1C[C@@H](CC(=O)OCC)OC(C)(C)O1.FC(F)(F)c1cccc(-c2c(Br)cnn2-c2ccnc(Nc3ccccc3)n2)c1>>CCOC(=O)C[C@H]1C[C@@H](/C=C/c2cnn(-c3ccnc(Nc4ccccc4)n3)c2-c2cccc(C(F)(F)F)c2)OC(C)(C)O1,,CN(C)C=O,,CCN(CC)CC,,test
US06001997,CCCCP(CCCC)(CCCC)=C(C(=O)OC(C)(C)C)N1C(=O)[C@@H](NC(=O)Cc2ccccc2)[C@H]1SCC(=O)C1CCOC1>>CC(C)(C)OC(=O)C1=C(C2CCOC2)CS[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N12,,Cc1ccccc1,,CCCCCC,CCOC(C)=O,test
US05506190,NCc1ccco1.O=C1C2=C(CCCC2)C(=O)N1c1cc(OC2CCCC2)c(Cl)cc1F>>O=C(NCc1ccco1)C1=C(C(=O)Nc2cc(OC3CCCC3)c(Cl)cc2F)CCCC1,,CC#N,,,,test
US05504244,CC(=O)O.CCCCCCCc1ccc(C(=O)Cc2cccc(C#N)c2)cc1.O=S(=O)(O)O>>CCCCCCCc1ccc(C(=O)Cc2cccc(C(=O)O)c2)cc1,,O,O=S(=O)(O)O,,,test
US20100048639A1,CC(C)Oc1ccc(C(=O)O)cc1Cl.N=C(NO)c1ccc(CO)cc1>>CC(C)Oc1ccc(-c2nc(-c3ccc(CO)cc3)no2)cc1Cl,,CN(C)C=O,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US04350815,N#Cc1cc2c(nc1N)ONC2(N)c1ccccc1.O>>N#Cc1c(O)nc2onc(-c3ccccc3)c2c1N,,Cl,,O=N[O-].[Na+],,test
US20060161024A1,C/C(=C\CO)C1CCCCC1>>C/C(=C\C=O)C1CCCCC1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,O=S([O-])([O-])=S.[Na+].[Na+],test
US20070287697A1,CCC1CN=C2[C@H](N)CC[C@@H](c3cccc(F)c3F)CN21.O=C(Cl)N1CCC(n2c(=O)[nH]c3ncccc32)CC1>>CCC1CN=C2[C@H](NC(=O)N3CCC(n4c(=O)[nH]c5ncccc54)CC3)CC[C@@H](c3cccc(F)c3F)CN21,,ClCCl,,CCN(CC)CC,O=C([O-])O.[Na+],test
US20100009959A1,CC(=O)Nc1cccc(B(O)O)c1N.COC(=O)c1ccc2cc[nH]c2c1.O=C([O-])c1ccc2c(C3CCCCC3)c(Br)[nH]c2c1>>COC(=O)c1ccc2c(C3CCCCC3)c(-c3cccc(NC(C)=O)c3N)[nH]c2c1,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,C1COCCO1,,O=C([O-])[O-].[Na+].[Na+],,test
US20030207926A1,CCN.Cc1nsc(NC(=O)C(=CN(C)C)c2ccc3oc(CC(C)(C)C)nc3c2)c1Cl>>CCNC=C(C(=O)Nc1snc(C)c1Cl)c1ccc2oc(CC(C)(C)C)nc2c1,,C1CCOC1,O,Cl,,test
US20060135541A1,O=C(Cn1ccc([N+](=O)[O-])n1)Nc1cccc(F)c1>>Nc1ccn(CC(=O)Nc2cccc(F)c2)n1,[Pd],CCO,CCOC(C)=O,,,test
US05162334,C=CCOC1CC(C=C(C)C2OC(=O)C3CCCCN3C(=O)C(=O)C3(O)OC(C(OC)CC(C)CC(C)=CC(CC)C(=O)CC(O[Si](C)(C)C(C)(C)C)C2C)C(OC)CC3C)CCC1O.O=[N+]([O-])c1ccccc1S(=O)(=O)Cl>>C=CCOC1CC(C=C(C)C2OC(=O)C3CCCCN3C(=O)C(=O)C3(O)OC(C(OC)CC(C)CC(C)=CC(CC)C(=O)CC(O[Si](C)(C)C(C)(C)C)C2C)C(OC)CC3C)CCC1OS(=O)(=O)c1ccccc1[N+](=O)[O-],CN(C)c1ccncc1,CCOC(C)=O,ClCCl,CCN(C(C)C)C(C)C,,test
US20140080808A1,CSC1=NCCS[C@@](C)(CO[Si](C)(C)C(C)(C)C)C1.N#Cc1ccc(-c2ccc(C3(C(=O)NN)CC3)cc2)nc1>>CC(C)(C)[Si](C)(C)OC[C@@]1(C)Cc2nnc(C3(c4ccc(-c5ccc(C#N)cn5)cc4)CC3)n2CCS1,,CCCCO,,,,test
US20150175614A1,CCOC(=O)c1cc2n(n1)CCNC2.O=C(O)Cc1c[nH]c2ccccc12>>CCOC(=O)c1cc2n(n1)CCN(C(=O)Cc1c[nH]c3ccccc13)C2,,ClCCl,,CN1CCOCC1,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090270361A1,Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1C(=O)Cl.NCc1ccoc1>>Cc1nn(-c2ccc(C#N)c(Cl)c2)c(C)c1C(=O)NCc1ccoc1,,CC(=O)N(C)C,,,,test
US20100029710A1,CCc1nc2c(C)cc(CO)nc2n1[C@H]1CCc2cc(Br)ccc21.CS(=O)(=O)Cl>>CCc1nc2c(C)cc(COS(C)(=O)=O)nc2n1[C@H]1CCc2cc(Br)ccc21,,ClCCl,,CCN(CC)CC,,test
US20050176701A1,C=CC(O)C1CCCC1.Fc1cc(Br)ccc1C(F)F>>O=C(CCc1ccc(C(F)F)c(F)c1)C1CCCC1,,CN1CCCC1=O,,O,O=C([O-])O.[Na+],test
US20060194787A1,COc1ccc2oc(C(=O)N[C@@H](CC(C)C)C(=O)NC3CC(C)CN(S(=O)(=O)c4ccccn4)CC3O)cc2c1>>COc1ccc2oc(C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]3C[C@H](C)CN(S(=O)(=O)c4ccccn4)CC3=O)cc2c1,,ClCCl,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US04477276,CCOC(=O)C(C)Oc1ccc(O)cc1.CS(=O)(=O)c1nc2ccc(Cl)nc2s1>>CCOC(=O)C(C)Oc1ccc(Oc2nc3ccc(Cl)nc3s2)cc1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20130281434A1,COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(N)sc2c1-c1ccc(Cl)cc1.COC1C=CC(OC)O1>>COC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(N3CC=CC3=O)sc2c1-c1ccc(Cl)cc1,,CC#N,CCOC(C)=O,Cl,,test
US20010018525A1,CCCCCCCCNc1ccccc1.Nc1c(-c2cccc(C(F)(F)F)c2)cc(C(=O)O)cc1-c1cccc(C(F)(F)F)c1>>Nc1c(-c2cccc(C(F)(F)F)c2)cc(C(=O)NCCCCCCCCc2ccccc2)cc1-c1cccc(C(F)(F)F)c1,,CN(C)C=O,,O=C(n1ccnc1)n1ccnc1,,test
US20110118261A1,CS(=O)(=O)Cl.OC1CCN(c2ccc(Br)cn2)C1>>CS(=O)(=O)OC1CCN(c2ccc(Br)cn2)C1,,ClCCl,,CCN(CC)CC,,test
US20120157432A1,COC(=O)c1ccc(C2OC2CC[C@@H](NC(=O)OCc2ccccc2)[C@H](O[Si](C)(C)C(C)(C)C)c2ccccc2)cc1>>COC(=O)c1ccc(CC(=O)CC[C@@H](NC(=O)OCc2ccccc2)[C@H](O[Si](C)(C)C(C)(C)C)c2ccccc2)cc1,,CCO,,c1ccc(P(c2ccccc2)c2ccccc2)cc1,,test
US20100234219A1,COC(=O)c1ccc(C=O)c2ccccc12.NO>>COC(=O)c1ccc(C=NO)c2ccccc12,,CO,,,,test
US20130157997A1,COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc2cc(-c3ncc(-c4ccc5[nH]c([C@@H]6CCCN6C(=O)[C@@H](NC(=O)OC)C(C)C)nc5c4)c(OCc4ccccc4)n3)ccc2[nH]1)C(C)C>>COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1nc2cc(-c3ncc(-c4ccc5[nH]c([C@@H]6CCCN6C(=O)[C@@H](NC(=O)OC)C(C)C)nc5c4)c(O)n3)ccc2[nH]1)C(C)C,[Pd],CO,,,,test
US20050043388A1,COC(=O)CCC(=O)Nc1ccc(C(=O)NN=C2C(=O)Nc3ccc(I)cc32)cc1>>O=C(O)CCC(=O)Nc1ccc(C(=O)NN=C2C(=O)Nc3ccc(I)cc32)cc1,,C1CCOC1,O,[Na+].[OH-],,test
US20040132669A1,CC(=O)OC[C@H]1O[C@@H](Oc2n[nH]c(C(F)(F)F)c2Cc2ccc(CCCO)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O>>OCCCc1ccc(Cc2c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)n[nH]c2C(F)(F)F)cc1,,CO,,C[O-].[Na+],,test
US20100197683A1,BrB(Br)Br.CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(C(C)CC)c2nc(COC)nn12>>CCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(C(C)CC)c2nc(CBr)nn12,,ClCCl,,Cl,O=C([O-])O.[Na+],test
US20040006134A1,N#Cc1ccc(Br)cc1Cl.OB(O)c1ccc(F)cc1F>>N#Cc1ccc(-c2ccc(F)cc2F)cc1Cl,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,CN(C)C=O,,O,O=P([O-])([O-])[O-].[K+].[K+].[K+],test
US20090306052A1,CNC(=O)c1ccc(Cl)nc1.Oc1ccc2c(c1)CC(N1CCCCC1)C2>>CNC(=O)c1ccc(Oc2ccc3c(c2)CC(N2CCCCC2)C3)nc1,,CN(C)C=O,,[H-].[Na+],,test
US20150025058A1,I.Nc1nc2c(Cl)nccn2n1>>Nc1nc2c(I)nccn2n1,,O,,[Na+].[OH-],,test
US05538973,CCOC(=O)c1cc2cc(Cn3ccnc3)ccc2[nH]1.ClCCCBr>>CCOC(=O)c1cc2cc(Cn3ccnc3)ccc2n1CCCCl,,CCOC(C)=O,CN(C)C=O,O,[H-].[Na+],test
US04413006,CN=C=O.COc1cc(N)ccc1OCCCN1CCN(c2ccccc2)CC1>>CNC(=O)Nc1ccc(OCCCN2CCN(c3ccccc3)CC2)c(OC)c1,,c1ccccc1,,,,test
US20100331293A1,CC(=O)c1ccc(S(C)(=O)=O)c(-c2nc3cc(F)cc(F)c3c(Nc3cncc(N4CCOCC4)c3)c2C)c1>>Cc1c(-c2cc(C(C)O)ccc2S(C)(=O)=O)nc2cc(F)cc(F)c2c1Nc1cncc(N2CCOCC2)c1,,C1CCOC1,,[Al+3].[H-].[H-].[H-].[H-].[Li+],,test
US04436662,Cc1[nH]cc2c1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2.NC(=O)CCl>>Cc1c2c(cn1CC(N)=O)CN=C(c1ccccc1Cl)c1cc(Cl)ccc1-2,,CN(C)C=O,O,CC(C)(C)[O-].[K+],,test
US20100130496A1,Cc1cccc(CC#N)n1>>Cc1cccc(CCN)n1,,C1CCOC1,,CO,Cl,test
US20030171377A1,COC(=O)C(Cc1ccc(C#CCc2nc(-c3ccccc3)oc2C)cc1)c1ccccc1>>COC(=O)C(Cc1ccc(CCCc2nc(-c3ccccc3)oc2C)cc1)c1ccccc1,[Pd],CO,,,,test
US04810713,O=S(Cl)Cl.OCCCOc1cccc2cccnc12>>ClCCCOc1cccc2cccnc12,,c1ccccc1,,,,test
US20120053204A1,C/C=C/c1nc2cc(C(F)(F)F)ccc2c(C)c1C(=O)OCC>>C/C=C/c1nc2cc(C(F)(F)F)ccc2c(C)c1C(=O)O,,CCO,O,[Na+].[OH-],,test
US05629264,C#CCBr.CCC1NC(c2ccccc2)=NC(=O)C1C>>C#CCN1C(=O)C(C)C(CC)N=C1c1ccccc1,,C1CCOC1,Cc1ccccc1,[Li]CCCC,,test
US20090023767A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1[nH]nc2c1c(=O)n(CC(F)CNC(=O)OC(C)(C)C)c1cc3c(cc21)CCCC3>>Cc1c2c(=O)n(CC(F)CNC(=O)OC(C)(C)C)c3cc4c(cc3c2nn1C(=O)OC(C)(C)C)CCCC4,CN(C)c1ccncc1,CN(C)C=O,,,,test
US20080108608A1,Cn1nc(C2CC2)cc1N.O=C(Nc1cccc(C#Cc2cnc(Cl)nc2)c1)Oc1ccccc1>>Cn1nc(C2CC2)cc1NC(=O)Nc1cccc(C#Cc2cnc(Cl)nc2)c1,,C1CCOC1,CCN(CC)CC,,,test
US20110166123A1,Fc1ccc(I)c(F)n1.O=C=O>>O=C(O)c1cc(I)c(F)nc1F,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20050277690A1,CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)O.CCN=C=NCCCN(C)C.On1nnc2ccccc21>>CN(C)c1ccc(CNC(=O)[C@@H](Cc2ccccc2)NC(=O)OC(C)(C)C)cc1,,ClCCl,,CCN(CC)CC,,test
US03945998,CC1(CO)COC(c2ccccc2)=N1.ClCc1ccccc1>>CC1(COCc2ccccc2)COC(c2ccccc2)=N1,,Cc1ccccc1,,[H-].[Na+],,test
US20150166564A1,COc1nn(-c2ccccc2)c(F)c1C(F)(F)F.NN>>COc1nn(-c2ccccc2)c(N)c1C(F)(F)F,[Ni],COCCOC,,CCN(CC)CC,,test
US20050203110A1,CCCC(=O)OC(=O)CCC.NCc1ccccc1.Nc1cccnc1C(=O)O>>CCCC(=O)Nc1cccnc1C(=O)NCc1ccccc1,,CCOC(C)=O,,O=C([O-])O.[Na+],,test
US20150045356A1,O=P(O)(O)O.O=c1ccc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc2[nH]1>>O=P(O)(O)O.O=c1ccc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc2[nH]1,,CO,ClCCl,,,test
US20030119889A1,C#CCNC(=S)Nc1cc(Cl)ccc1C.CCOC(=O)C(=O)Cl>>C#CCN1C(=O)C(=O)N(c2cc(Cl)ccc2C)C1=S,,ClCCl,,,,test
US04152319,C=CC(=O)Cl.CC(C)(C)c1cc(N)cc(C(C)(C)C)c1O>>C=CC(=O)Nc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1,,c1ccccc1,,O=C([O-])[O-].[Na+].[Na+],,test
US20100093730A1,CC(C)(C)OC(=O)N1CCN(CC(=O)O)C(=O)C1c1ccccc1.c1ccc(C(c2ccccc2)N2CCNCC2)cc1>>CC(C)(C)OC(=O)N1CCN(CC(=O)N2CCN(C(c3ccccc3)c3ccccc3)CC2)C(=O)C1c1ccccc1,,ClCCl,,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20030153599A1,CCOC(=O)C1CCc2ccc(O)cc2O1.ClCc1ccccc1>>CCOC(=O)C1CCc2ccc(OCc3ccccc3)cc2O1,,CC(C)=O,,[I-].[K+],,test
US20160031892A1,COC(=O)C1CN(c2ncnn3cc(Br)cc23)C1>>O=C(O)C1CN(c2ncnn3cc(Br)cc23)C1,,CO,O,[Na+].[OH-],,test
US20160108047A1,CC(=O)ON=C(C)c1cccc(C)c1O>>Cc1noc2c(C)cccc12,,c1ccncc1,,,,test
US20100048568A1,NN1CCCCC1.O=C(O)c1cnc(-c2ccccc2)nc1>>O=C(NN1CCCCC1)c1cnc(-c2ccccc2)nc1,,ClCCl,,CCN=C=NCCCN(C)C,On1nnc2ccccc21,test
US05679696,COc1ccc(C(=O)Cl)cc1OC1CCCC1.Nc1c(Cl)cncc1Cl>>COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)cc1OC1CCCC1,,C1CCOC1,ClCCl,Cl,[H-].[Na+],test
US20130072473A1,NC(=O)c1c(N)sc2c1CCCC2.O=C(Cl)c1ccccc1Cl>>NC(=O)c1c(NC(=O)c2ccccc2Cl)sc2c1CCCC2,,ClCCl,,CCN(CC)CC,,test
US04584293,COc1ccc2c(c1)CC(N(C)CCCNC(=O)Cc1cc(OC)c(OC)cc1[N+](=O)[O-])CC2>>COc1ccc2c(c1)CC(N(C)CCCNC(=O)Cc1cc(OC)c(OC)cc1N)CC2,,CCO,,ClCCl,,test
US20080207616A1,CC(C)(C#N)c1cccs1.CN(C)C=O>>CC(C)(C#N)c1ccc(C=O)s1,,C1CCOC1,,[Li]C(C)(C)C,,test
US05143643,CCCCCCCCOC(C)C(=O)OCC>>CCCCCCCCOC(C)CO,,CCOCC,,Cl,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US04900754,CC1(C)CC(c2ccc(F)cc2)=C(/C=C/C(O)CC(O)CC(=O)O)C(C)(C)C1>>CC1(C)CC(c2ccc(F)cc2)=C(/C=C/[C@H]2C[C@H](O)CC(=O)O2)C(C)(C)C1,,Cc1ccccc1,,,,test
US20110118245A1,CCOc1cc2nc[nH]c(=O)c2cc1OCC.O=P(Cl)(Cl)Cl>>CCOc1cc2ncnc(Cl)c2cc1OCC,,Cc1ccccc1,,,,test
US20070010537A1,O=[N+]([O-])c1cccc(S(=O)(=O)Cl)c1.OCC1COc2ccccc2N1>>O=[N+]([O-])c1cccc(S(=O)(=O)N2c3ccccc3OCC2CO)c1,,C1CCOC1,,O,O=C([O-])O.[Na+],test
US04968698,CCCCOc1cccc(CC#N)c1>>CCCCOc1cccc(CCN)c1,[Ni],CO,,[H][H],,test
US20160222056A1,COC(=O)c1ccc(-c2ccc(C[C@H](NC(=O)[C@@H]3CC[C@@H](CNC(=O)OC(C)(C)C)CC3)C(=O)Nc3ccc4[nH]c(=O)[nH]c4c3)cc2)c(C)n1>>Cc1nc(C(=O)O)ccc1-c1ccc(C[C@H](NC(=O)[C@@H]2CC[C@@H](CNC(=O)OC(C)(C)C)CC2)C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc1,,C1CCOC1,O,[Li+].[OH-],,test
US04309407,CCCCCCOC(=O)Cc1ccc(C=CC(=O)CCCCC)s1>>CCCCCC(=O)C=Cc1ccc(CC(=O)O)s1,,CCO,O,[K+].[OH-],,test
US20060030613A1,CC(C)(C)c1ccc(CNCCc2cc(C(F)(F)F)ccc2F)cc1.O=C(O)c1cc(Cl)cc2cc[nH]c12>>CC(C)(C)c1ccc(CN(CCc2cc(C(F)(F)F)ccc2F)C(=O)c2cc(Cl)cc3cc[nH]c23)cc1,,CN(C)C=O,O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F,test
US20070027071A1,C=Cc1cccc2c1CN(C(=O)O[C@@H]1C[C@@H](C(=O)OC)N(C(=O)OC(C)(C)C)C1)C2.Cl>>C=Cc1cccc2c1CN(C(=O)O[C@H]1CN[C@H](C(=O)OC)C1)C2.Cl,,CCOC(C)=O,,,,test
US20150231143A1,CCN(CC)CC.CN(C)C=O.Cc1cc(-c2c(C(=O)O)sc(-c3ccc(Cl)cc3)c2C)ccc1S(N)(=O)=O.ClCCl.O=C(Cl)C(=O)Cl>>CON(C)C(=O)c1sc(-c2ccc(Cl)cc2)c(C)c1-c1ccc(S(=O)(=O)N=CN(C)C)c(C)c1,,ClCCl,ClCCl,,,test
US20130059853A1,CCCBr.COc1ccc(-c2cccc3c2CCC3=O)c(O)c1OCC1CC1>>CCCOc1c(-c2cccc3c2CCC3=O)ccc(OC)c1OCC1CC1,,CC#N,,O=C([O-])[O-].[K+].[K+],,test
US20110028493A1,CCOP(=S)([S-])OCC.COC(=O)c1ccc(CC#N)cc1>>COC(=O)c1ccc(CC(N)=S)cc1,,CCOC(C)=O,Cl,[Na+].[OH-],,test
US20050113450A1,COC(=O)c1cc(C#N)ccc1N.Cc1c(C(=O)O)cccc1S(=O)(=O)N1CCc2cc(Cl)ccc21>>Cc1c(C(=O)Nc2ccc(C#N)cc2C(=O)O)cccc1S(=O)(=O)N1CCc2cc(Cl)ccc21,,ClCCl,c1ccncc1,CN(C)C=O,O=C(Cl)C(=O)Cl,test
US20150344423A1,COC(=O)C(C)(C)CCNC(=O)c1nn(CC2CCCCC2)c(-c2ccc(S(=O)(=O)NC(C)(C)C)c(C(F)(F)F)c2)c1F>>CC(C)(C)NS(=O)(=O)c1ccc(-c2c(F)c(C(=O)NCCC(C)(C)C(=O)O)nn2CC2CCCCC2)cc1C(F)(F)F,,CO,O,[K+].[OH-],,test
US20090156646A1,CC(=O)Cl.Oc1cccc(Br)c1>>CC(=O)c1ccc(Br)cc1O,,ClCCCl,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US20080019915A1,COc1ccc([N+](=O)[O-])nc1Br>>COc1ccc(N)nc1Br,,CCO,,O,O=C([O-])O.[Na+],test
US20030078289A1,COc1ccc(Oc2c(Cl)cc([N+](=O)[O-])cc2Cl)cc1S(=O)(=O)Cl.NC1CCC1>>COc1ccc(Oc2c(Cl)cc([N+](=O)[O-])cc2Cl)cc1S(=O)(=O)NC1CCC1,,ClCCl,,CCN(CC)CC,,test
US20140275083A1,COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1.C[C@H](NC(=O)OC(C)(C)C)C(=O)NNC(=O)c1ccc(Cl)cc1>>C[C@H](NC(=O)OC(C)(C)C)c1nnc(-c2ccc(Cl)cc2)s1,,C1CCOC1,,,,test
US20120264728A1,CSc1nc(N)nc(C(C)O)n1.Oc1ccccc1Cl>>CSc1nc(N)nc(C(C)Oc2ccccc2Cl)n1,,C1CCOC1,,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US20040009998A1,CCOC(=O)CN.S=C=Nc1cc(Cl)cc(Cl)c1>>O=C1CNC(=S)N1c1cc(Cl)cc(Cl)c1,,ClCCl,,Cl,,test
US04940710,CC(=O)c1sccc1C.O=[Se]=O>>Cc1ccsc1C(=O)C=O,,C1COCCO1,O,,,test
US03936405,CC(O)C(=O)O.CN(C)CCO>>CC(O)C(=O)OCCN(C)C,,O,,CC(C)O,,test
US20160221994A1,C#CC(=O)OC(C)C.c1nc[nH]n1>>CC(C)OC(=O)/C=C/n1cncn1,,ClCCl,,CCN(CC)CC,,test
US20110130445A1,C[C@H]([C@H](C(=O)O)c1ccc(Cl)cc1)C(F)(F)F.O=C(Cl)C(=O)Cl>>C[C@H]([C@H](C(=O)Cl)c1ccc(Cl)cc1)C(F)(F)F,,ClCCl,,CN(C)C=O,,test
US06417192B1,O=C(CCCCCCCBr)c1ccc(Cl)cc1>>OC(CCCCCCCBr)c1ccc(Cl)cc1,,O,,CC(=O)O,[BH4-].[Na+],test
US20090209607A1,COC(=O)c1cc(-c2c(Cl)cnn2C)c(Cl)o1>>Cn1ncc(Cl)c1-c1cc(C(=O)O)oc1Cl,,C1CCOC1,,[Na+].[OH-],,test
US20140080808A1,CC(C)(C)[Si](C)(C)OC[C@@]1(C)Cc2nnc(C3(c4ccc(-c5ncco5)cc4)CC3)n2CCS1>>C[C@]1(CO)Cc2nnc(C3(c4ccc(-c5ncco5)cc4)CC3)n2CCS1,,CO,,Cl,,test
US20010027196A1,CCS.COc1cc(-c2nc(N)nc(S(C)(=O)=O)c2C#N)cc(OC)c1OC>>CCSc1nc(N)nc(-c2cc(OC)c(OC)c(OC)c2)c1C#N,,COCCOC,,C1CCC2=NCCCN2CC1,,test
US20080027056A1,Cc1cc(C(F)(F)F)cc(Cl)n1.O=C1CCC(=O)N1Br>>FC(F)(F)c1cc(Cl)nc(CBr)c1,,ClC(Cl)(Cl)Cl,,CC(C)(C#N)N=NC(C)(C)C#N,,test
US20130059834A1,CC(C)(N)CO.COc1ccc2c(c1)c(-c1cnc3c(n1)c(C(=O)O)cn3COCC[Si](C)(C)C)nn2C>>COc1ccc2c(c1)c(-c1cnc3c(n1)c(C(=O)NC(C)(C)CO)cn3COCC[Si](C)(C)C)nn2C,,CN(C)C=O,,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,,test
US20080274947A1,CC(C)(C)[Si](C)(C)OC(CCC1C(=O)N(c2ccc(F)cc2)C1c1ccc(OCC=CCBr)cc1OCc1ccccc1)c1ccc(F)cc1.c1c[nH]cn1>>CC(C)(C)[Si](C)(C)OC(CCC1C(=O)N(c2ccc(F)cc2)C1c1ccc(OCC=CCn2ccnc2)cc1OCc1ccccc1)c1ccc(F)cc1,,Cc1ccccc1,,,,test
US20090253758A1,C[C@H](O)[C@@H](N)C(=O)O.N#Cc1ccc(F)c(CCBr)c1Cl>>C=Cc1c(NC(C(=O)O)C(C)O)ccc(C#N)c1Cl,,CS(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20110269773A1,COC(=O)C1C(=O)COC1C.N=CN>>CC1OCc2ncnc(O)c21,,O,,Cc1ccccc1,O=C([O-])[O-].[Na+].[Na+],test
US08859538B2,C=O.CCOC(=O)c1nc(-c2ccccc2)n2c1CNCCC2>>CCOC(=O)c1nc(-c2ccccc2)n2c1CN(C)CCC2,,C1CCOC1,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04851387,CNC(=O)C(=C[C@@H]1OC(C)(C)N(C(=O)OCc2ccccc2)[C@H]1CC(C)C)CCOC1CCCCO1>>CNC(=O)C(CCOC1CCCCO1)C[C@H](O)[C@@H](N)CC(C)C,[Pd],CCO,,,,test
US05463011,COC(=O)COc1ccc(C(=O)NC(=O)Nc2ccc(C#N)cc2)cc1.S>>COC(=O)COc1ccc(C(=O)NC(=O)Nc2ccc(C(N)=S)cc2)cc1,,CCN(CC)CC,,c1ccncc1,,test
US20100311684A1,COc1ncnc2c1ccn2[C@@H]1O[C@H](CO)[C@H]2O[C@H]21>>COc1ncnc2c1ccn2[C@@H]1O[C@H](CO)C[C@H]1O,,C1CCOC1,,,,test
US08618115B2,COc1cc(-n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)ccc1OCC(C)(C)OC(=O)C(=O)OC(C)(C)C>>COc1cc(-n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)ccc1OCC(C)(C)OC(=O)C(=O)O,,ClCCl,O=C(O)C(F)(F)F,,,test
US20080214545A1,COC(=O)c1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccncc3)cc2)cc1.NCCN1CCCC1>>CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccncc3)cc2)n(-c2ccc(C(=O)NCCN3CCCC3)cc2)n1,,ClCCCl,,C[Al](C)C,,test
US20030211421A1,CCC[C@@H]1CC[C@@H](c2ccc(Br)cc2)CC1.O=C=O>>CCC[C@@H]1CC[C@@H](c2ccc(C(=O)O)cc2)CC1,,C1CCOC1,,Cl,[Mg],test
US20120277192A1,CC(C)(C)[Si](C)(C)OCCC(O)(CCO[Si](C)(C)C(C)(C)C)c1ncc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)s1>>OCCC(O)(CCO)c1ncc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)s1,,C1CCOC1,,CCCC[N+](CCCC)(CCCC)CCCC.[F-],,test
US06114358,O=C(O)c1cc(CCl)on1.O=S(Cl)Cl>>O=C(Cl)c1cc(CCl)on1,c1ccncc1,,,,,test
US20150336996A1,COc1ccc(O)c(C=NC2CCCCC2NC(=O)OC(C)(C)C)c1>>COc1ccc(O)c(CN[C@@H]2CCCC[C@H]2NC(=O)OC(C)(C)C)c1,,CO,,[BH4-].[Na+],,test
US20160237091A1,O=[N+]([O-])c1cc2c(cc1CNCc1ccccc1)c(-c1ccncc1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1>>Nc1cc2c(cc1CNCc1ccccc1)c(-c1ccncc1)nn2C(c1ccccc1)(c1ccccc1)c1ccccc1,[Zn],,,,,test
US09364481B2,CCOC(=O)C1CCNCC1.COc1ccc2nc(Cl)c(C(F)(F)F)nc2c1>>CCOC(=O)C1CCN(c2nc3ccc(OC)cc3nc2C(F)(F)F)CC1,,CC#N,,,,test
US20100009950A1,CC(C)(C)OC(=O)NCC=O.CC1(C)OCc2cc(Br)ccc2O1>>CC(C)(C)OC(=O)N(CCO)c1ccc2c(c1)COC(C)(C)O2,,C1CCOC1,CCOC(C)=O,CC(=O)O,[Li]CCCC,test
US20110263562A1,OC[C@@H]1CC[C@@H](n2cc3ccc(OCC4CC4)cc3n2)CC1>>O=C[C@@H]1CC[C@@H](n2cc3ccc(OCC4CC4)cc3n2)CC1,,CC#N,,CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21,,test
US20120010189A1,CN1CCNCC1.Cc1cc(C=O)ccc1O>>Cc1cc(CN2CCN(C)CC2)ccc1O,,CC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20070219234A1,C/C(=C(\C#N)C(=S)/N=C/N(C)C)N1CCC(O)CC1.NC(=O)CCl>>NC(=O)c1sc2nccc(N3CCC(O)CC3)c2c1N,,CN(C)C=O,,O,[Na+].[OH-],test
US20120202802A1,CC(C)(C)OC(=O)NCCC1(O)CCCC1C(=O)OCc1ccccc1>>CC(C)(C)OC(=O)NCCC1(O)CCCC1C(=O)O,[Pd],CO,,,,test
US20130267717A1,O=C1COC(=O)c2ccccc21.O=C[C@@H]1CC[C@@H](c2ccc(Cl)cc2)CC1>>O=C1O/C(=C\[C@@H]2CC[C@@H](c3ccc(Cl)cc3)CC2)C(=O)c2ccccc21,,CC(=O)O,,C,O=C[O-].[NH4+],test
US20040204427A1,CCc1ccc(N)cc1.Clc1ncc(CI)c(Cl)n1>>CCc1ccc(NCc2cnc(Cl)nc2Cl)cc1,,CC(C)=O,O,O=C([O-])[O-].[K+].[K+],,test
US20090318467A1,Cc1cc(-c2cccc(C(F)(F)F)c2)c(C(=O)O)nc1C(=O)N1CCC(N2CCCC2)CC1.Nc1cccnc1>>Cc1cc(-c2cccc(C(F)(F)F)c2)c(C(=O)Nc2cccnc2)nc1C(=O)N1CCC(N2CCCC2)CC1,,CN(C)C=O,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20070161654A1,COCc1onc(-c2ccc(F)cc2)c1C(=O)O.O=S(Cl)Cl>>COCc1onc(-c2ccc(F)cc2)c1C(=O)Cl,CN(C)C=O,,,,,test
US20050085639A1,CCS(=O)(=O)Nc1nc(-c2ncccn2)nc(OCCO)c1Oc1ccccc1OC.CSc1cnc(Cl)nc1>>CCS(=O)(=O)Nc1nc(-c2ncccn2)nc(OCCOc2ncc(SC)cn2)c1Oc1ccccc1OC,,C1CCOC1,,O=C(O)CC(O)(CC(=O)O)C(=O)O,[H-].[Na+],test
US20090209607A1,Cn1ncc(Cl)c1-c1csc(C(=O)NC(Cc2ccccc2)CN(C(=O)[O-])C(C)(C)C)c1>>Cn1ncc(Cl)c1-c1csc(C(=O)NC(CN)Cc2ccccc2)c1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20090023703A1,CCOC(=O)c1cc2nc(OC)ccc2[nH]1>>COc1ccc2[nH]c(C(=O)O)cc2n1,,CCO,,CC(=O)O,[Na+].[OH-],test
US20030207883A1,O=[N+]([O-])c1ccc(Cl)nc1.Oc1cccc2[nH]ccc12>>O=[N+]([O-])c1ccc(Oc2cccc3[nH]ccc23)nc1,,CN1CCCC1=O,,O,[H-].[Na+],test
US05719161,COCCOC(=O)Nc1cccc(C)c1CCl.Cc1nc2c(O)cccn2c1C=O>>COCCOC(=O)Nc1cccc(C)c1COc1cccn2c(C=O)c(C)nc12,,CC(C)=O,,[I-].[Na+],,test
US06548126B1,CCCC1CCC(c2ccc(O)cc2)CC1.CCOc1ccc(C(=O)O)c(F)c1F>>CCCC1CCC(c2ccc(OC(=O)c3ccc(OCC)c(F)c3F)cc2)CC1,CN(C)c1ccncc1,ClCCl,,CCOCC,,test
US20120289702A1,Fc1ccc2cccnc2c1F.O=C1CCC(=O)N1I>>Fc1ccc2cc(I)cnc2c1F,,CC(=O)O,,,,test
US20100168418A1,COc1ccnc2cc(C(F)(F)F)ccc12.O=C(OO)c1cccc(Cl)c1>>COc1cc[n+]([O-])c2cc(C(F)(F)F)ccc12,,ClC(Cl)Cl,,O=C([O-])O.[Na+],,test
US20100063054A1,CC(C)(O)c1ccc(NNC(=S)Nc2ccc([N+](=O)[O-])cc2)nc1>>CC(C)(O)c1ccc2nnc(S)n2c1,,COCCOC,,,,test
US20080027065A1,C[C@H]1CNCCN1C(=O)OC(C)(C)C.O=[N+]([O-])c1ccc(CBr)c(F)c1>>C[C@H]1CN(Cc2ccc([N+](=O)[O-])cc2F)CCN1C(=O)OC(C)(C)C,,CN(C)C=O,,CCN(C(C)C)C(C)C,,test
US05763700,Brc1cccc(Oc2ccccc2)c1.CCOc1ccc(C2(C=C(F)COC(C)=O)CC2)cc1>>CCOc1ccc(C2(C=C(F)Cc3cccc(Oc4ccccc4)c3)CC2)cc1,,C1CCOC1,,[Mg],,test
US20150252030A1,COC(=O)CBr.Cc1cccc(-c2ccoc2)c1O>>COC(=O)COc1c(C)cccc1-c1ccoc1,,CC#N,,O=C([O-])[O-].[Cs+].[Cs+],,test
US20100152190A1,CC(C)(C)OC(=O)C/N=C/CC1CCCC1.N#C/C(=C\c1cccc(Cl)c1F)c1ccc(Cl)cc1>>CC(C)(C)OC(=O)C1NC(CC2CCCC2)C(C#N)(c2ccc(Cl)cc2)C1c1cccc(Cl)c1F,,ClCCl,,CCN(CC)CC,,test
US20060234997A1,COC=Cc1ccc(OCCCCOCc2ccccc2)nc1NC(=O)C(C)(C)C>>COC=Cc1ccc(OCCCCOCc2ccccc2)nc1N,,CCO,,[K+].[OH-],,test
US20110195954A1,CC1(C)C(=O)Nc2ccc(F)c(F)c21>>CC1(C)CNc2ccc(F)c(F)c21,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20130102621A1,CC(C)(C)OC(=O)N1CCC(COS(C)(=O)=O)CC1.[C-]#N>>CC(C)(C)OC(=O)N1CCC(CC#N)CC1,,CCO,,O,,test
US20040142989A1,N#Cc1ccccc1Nc1ccc(C(F)(F)F)cc1N.O=C1OS(=O)(=O)c2c(Br)c(Br)c(Br)c(Br)c21>>N#Cc1ccc(Nc2ccc(C(F)(F)F)cc2NC(=O)c2c(Br)c(Br)c(Br)c(Br)c2S(=O)(=O)O)cc1,,C1CCOC1,,CCN(CC)CC,Cl,test
US04882359,BrCCCBr.CCCCCCCCO.O=C1CCCCCN1>>CCCCCCCCOCCCN1CCCCCC1=O,,Cc1ccccc1,,[H-].[Na+],,test
US20150018343A1,Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccc(F)cc1OCCNC(=O)OC(C)(C)C)C3.Cl>>Cc1nc2c3c(nn2c(C)c1Cl)CN(C(=O)c1ccc(F)cc1OCCN)C3.Cl,,ClCCl,,C1COCCO1,,test
US20050194140A1,C=C(C)C(=O)OCCN(C)C.C=CC(=O)O>>C=C(C)C(=O)OCCN(C)C.C=CC(=O)O,,O,,,,test
US20030105139A1,COc1cc2c(cc1C(F)(F)F)NCC2.O=C(Nc1cc(-c2ccccc2)cc(-c2cccnc2)c1)Oc1ccccc1>>COc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1cc(-c3ccccc3)cc(-c3cccnc3)c1)CC2,,CN(C)C=O,,,,test
US20080114002A1,CS(=O)(=O)c1ccc(F)c(Cl)c1.O=C(O)Cc1ccc(F)cc1O>>CS(=O)(=O)c1ccc(Oc2cc(F)ccc2CC(=O)O)c(Cl)c1,,CN(C)C=O,,[H-].[Na+],,test
US20050070714A1,COCC(=O)OC.Cc1oc(-c2ccccc2)nc1CCOc1ccc(C=O)c2sccc12>>COC(=O)C(OC)C(O)c1ccc(OCCc2nc(-c3ccccc3)oc2C)c2ccsc12,Cl[Ti](Cl)(Cl)Cl,C1CCOC1,ClCCl,CCN(C(C)C)C(C)C,,test
US20120238564A1,Clc1nccn2c(-c3cccc(Br)n3)cnc12.NCCN1CCOCC1>>Brc1cccc(-c2cnc3c(NCCN4CCOCC4)nccn23)n1,,CC(C)O,,CCN(CC)CC,O,test
US04804400,CC(C)Oc1cc(N)c(F)cc1Cl.CC1=C(C)C(=O)OC1=O>>CC1=C(C)C(=O)N(c2cc(OC(C)C)c(Cl)cc2F)C1=O,,CC(=O)O,,,,test
US20110319378A1,O=C1CC[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N1C(CO)CCCO>>O=C1CC[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N1C1CCCOC1,,C1CCOC1,CCOC(C)=O,CC(C)OC(=O)N=NC(=O)OC(C)C,c1ccc(P(c2ccccc2)c2ccccc2)cc1,test
US06797726B1,CN(C)CCOCCc1cccc2ccsc12.Cl>>CN(C)CCOCCc1cccc2ccsc12.Cl,,CCOC(C)=O,,,,test
US04663324,Cn1ncc(SCc2ccccc2)c(Cl)c1=O.O=C(OO)c1cccc(Cl)c1>>Cn1ncc(S(=O)Cc2ccccc2)c(Cl)c1=O,,ClCCl,,,,test
US20040058905A1,CC(C)I.C[C@H]1CCC[C@@H](C)N1CCNC(=O)[C@@H]1CCCCN1c1nc2ccc(O)cc2o1>>CC(C)Oc1ccc2nc(N3CCCC[C@H]3C(=O)NCCN3[C@@H](C)CCC[C@H]3C)oc2c1,,CN(C)C=O,,[H-].[Na+],,test
US20090192150A1,CCOC(=O)c1cc(CNC(=S)NC(=O)OCC2c3ccccc3-c3ccccc32)nc(OC)c1>>CCOC(=O)c1cc(OC)n2c(=N)[nH]cc2c1,,Cc1ccccc1,,C(=NC1CCCCC1)=NC1CCCCC1,,test
US05556864,CC(C)(C)OC(=O)N1C[C@H](O)CC1COc1ccccc1CCc1ccccc1.Cl>>Cl.O[C@H]1CNC(COc2ccccc2CCc2ccccc2)C1,,C1COCCO1,,,,test
US20040138286A1,CN(C(=O)C(F)(F)F)c1ccc2[nH]ncc2c1>>CNc1ccc2[nH]ncc2c1,,CO,O,O=C([O-])[O-].[K+].[K+],,test
US20160122331A1,COC(=O)c1cccc(C2CC(N)CCO2)c1.O=C(O)C1(c2ccc3c(c2)OC(F)(F)O3)CC1>>COC(=O)c1cccc([C@H]2C[C@@H](NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)CCO2)c1,CN(C)C=O,ClCCl,,CCN(CC)CC,O=C(Cl)C(=O)Cl,test
US20160152605A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CSc1ccc(C2CCCCN2)cc1>>CSc1ccc(C2CCCCN2C(=O)OC(C)(C)C)cc1,CN(C)c1ccncc1,CC#N,,,,test
US20070042974A1,CCOC(=O)Cl.C[C@@H](O)CN>>CCOC(=O)NC[C@@H](C)O,,C1COCCO1,,O,[Na+].[OH-],test
US04925838,CC(C)(C)[Si](C)(C)O[C@@H]1C[C@@H](CN2CC(=O)NC2=O)N(C(=O)OCc2ccc([N+](=O)[O-])cc2)C1>>O=C1CN(C[C@@H]2C[C@@H](O)CN2C(=O)OCc2ccc([N+](=O)[O-])cc2)C(=O)N1,,CO,,Cl,,test
US20130252958A1,BrCc1ccccc1.N#Cc1nn(-c2ccccc2)c(=O)[nH]c1=O>>N#Cc1nn(-c2ccccc2)c(=O)n(Cc2ccccc2)c1=O,,O,,CN(C)C=O,[H-].[Na+],test
US20110144090A1,CCn1cc(CCN2Cc3ccccc3C2)c2c(OCc3ccccc3)cc(F)cc21>>CCn1cc(CCN2Cc3ccccc3C2)c2c(O)cc(F)cc21,[Pd],CO,,,,test
US20090048239A1,C=CCCC(=O)Cl.O=C1N[C@@H](Cc2ccccc2)CO1>>C=CCCC(=O)N1C(=O)OC[C@@H]1Cc1ccccc1,,C1CCOC1,,CCCCCC,[Li]CCCC,test
US20120323002A1,Clc1cc(N2CCOCC2)c2nc(-c3ccccc3)cn2n1.NN>>NNc1cc(N2CCOCC2)c2nc(-c3ccccc3)cn2n1,,CN(C)C=O,O,O=C([O-])[O-].[K+].[K+],,test
US05556909,CCOC(=O)C1C2CCC(C2)N1S(=O)(=O)NC(=O)OCc1ccccc1>>CCOC(=O)C1C2CCC(C2)N1S(N)(=O)=O,[Pd],CO,,,,test
US20150299121A1,COC(=O)C(C)C1CCC1>>CC(C(=O)O)C1CCC1,,C1CCOC1,O,[Li+].[OH-],,test
US20050137226A1,Cl.c1cc(Oc2ccc(OC3CN4CCC3CC4)cc2)cs1>>Cl.c1cc(Oc2ccc(OC3CN4CCC3CC4)cc2)cs1,,CCOC(C)=O,,C1COCCO1,,test
US05952325,COC(=O)C1CC(C#N)(c2ccccc2F)CCC1=O>>N#CC1(c2ccccc2F)CCC(=O)CC1,,O,,Cl,,test
US20110312945A1,CN(c1ccccc1)S(=O)(=O)c1ccccc1C=O.Cc1cc2c([nH]1)CC(C)(C)CC2=O>>Cc1[nH]c2c(c1C(O)c1ccccc1S(=O)(=O)N(C)c1ccccc1)C(=O)CC(C)(C)C2,,CO,O,[Na+].[OH-],,test
US20100261710A1,COC(=O)C(=O)c1cn2c3c(cccc13)CCC2>>O=C(O)C(=O)c1cn2c3c(cccc13)CCC2,,C1CCOC1,O,[Li+].[OH-],,test
US20060205774A1,Ic1ccc(OCCCN2CCCCC2)cc1.O=C1CCN(Cc2ccccc2)CC1>>OC1(c2ccc(OCCCN3CCCCC3)cc2)CCN(Cc2ccccc2)CC1,,C1CCOC1,,[Li]CCCC,[Cl-].[NH4+],test
US20150157739A1,COc1cc(C=O)cc(OC)c1O.O=C(O)CCl.Sc1ncc(-c2ccncc2)[nH]1>>COc1cc(/C=c2\sc3nc(-c4ccncc4)cn3c2=O)cc(OC)c1O,,CC(=O)O,O,CC(=O)[O-].[Na+],,test
US20090227541A1,O=Cc1cccc(OCCCOCc2ccccc2)c1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>O=Cc1cccc(OCCCOCc2ccccc2)c1OS(=O)(=O)C(F)(F)F,,ClCCl,,c1ccncc1,,test
US20080107608A1,CCCCCC.CN1CCCC1=O.COc1cc(OC(F)(F)F)ccc1-c1ncc(Br)cc1C>>CCC(CC)Oc1cnc(-c2ccc(OC(F)(F)F)cc2OC)c(C)c1,,CCCCCC,,CCOC(C)=O,,test
US20110071148A1,COc1ccc(C(=O)O)c(N)c1.O=C(Cl)c1ccccc1>>COc1ccc2c(=O)oc(-c3ccccc3)nc2c1,,c1ccncc1,,,,test
US05576321,Clc1ccc2c(c1Cl)CCNCC2.O=C(O)C(=O)O.c1cc(OC[C@@H]2CO2)c2cc[nH]c2c1>>O=C(O)C(=O)O.O[C@H](COc1cccc2[nH]ccc12)CN1CCc2ccc(Cl)c(Cl)c2CC1,,CCOC(C)=O,,CO,,test
US20110124635A1,CC(C)(O)C[C@]1(c2ccccc2)CCN([C@H]2CCCN(C(=O)OC(C)(C)C)C2)C(=O)O1>>CC(C)(O)C[C@]1(c2ccccc2)CCN([C@H]2CCCNC2)C(=O)O1,,ClCCl,O=C(O)C(F)(F)F,,,test
US20120202785A1,O=[N+]([O-])c1cccc(F)c1Nc1ccccc1>>Nc1cccc(F)c1Nc1ccccc1,[Pd],,,,,test
US20040180896A1,CI.Cn1ncc2cc(Oc3ccc(F)cc3CNC(=O)OC(C)(C)C)ccc21>>CN(Cc1cc(F)ccc1Oc1ccc2c(cnn2C)c1)C(=O)OC(C)(C)C,,CN(C)C=O,,[H-].[Na+],[Cl-].[NH4+],test
US20060167023A1,O=C(N1CCc2cc(C(F)(F)F)ccc2C1)C(F)(F)F>>FC(F)(F)c1ccc2c(c1)CCNC2,,CCO,,[Na+].[OH-],,test
US04301171,CCOC(=N)CC1COc2ccccc2O1.Cl.Nc1ccccc1N>>Cl.c1ccc2c(c1)OCC(Cc1nc3ccccc3[nH]1)O2,,CCO,,[NH4+].[OH-],,test
US05733914,CN1CCN(CCCCN)CC1.CSc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1>>CN1CCN(CCCCNc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)CC1,,CCOCC,,,,test
US20040116518A1,CC(=O)N1CCN(C(=O)/C=C/c2ccc(Sc3c(Cl)cccc3C=O)c(Cl)c2)CC1.Ic1ccc2[nH]ccc2c1>>CC(=O)N1CCN(C(=O)/C=C/c2ccc(Sc3ccc4[nH]ccc4c3)c(Cl)c2)CC1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US05055221,CCCCCCc1ccc(-c2ncc(O)cn2)cc1.CCCc1ccc(CBr)cc1>>CCCCCCc1ccc(-c2ncc(OCc3ccc(CCC)cc3)cn2)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20080021026A1,CC(C)OB(OC(C)C)OC(C)C.Cc1c(Br)sc2ccc(Cl)cc12>>Cc1c(B(O)O)sc2ccc(Cl)cc12,,C1CCOC1,Cc1ccccc1,[Li]CCCC,,test
US04177292,CN(C)[C@@H]1CCc2ccccc2[C@H](O)C1.Fc1ccc(Br)cc1>>CN(C)[C@@H]1CCc2ccccc2[C@H](Oc2ccc(Br)cc2)C1,,CS(C)=O,,[H-].[Na+],,test
US05049671,NC(CO)CO.Nc1nc(Cl)c2ncn([C@H]3C=C[C@@H](CO)C3)c2n1>>Nc1nc(NC(CO)CO)c2ncn([C@H]3C=C[C@@H](CO)C3)c2n1,,CO,,Cl,[Na+].[OH-],test
US09249115B2,CC(C)(C)OC(=O)N1CCNCC1.CCOc1ccc(C=O)c(OCC)c1OCC>>CCOc1ccc(CN2CCN(C(=O)OC(C)(C)C)CC2)c(OCC)c1OCC,CC(=O)O,ClCCl,,O=C([O-])O.[Na+],,test
US20080293770A1,C=Cc1cc(NC2CCN(C3CCOCC3)CC2)c([N+](=O)[O-])cc1F>>CCc1cc(NC2CCN(C3CCOCC3)CC2)c(N)cc1F,[Pd],CO,,O=C[O-].[NH4+],,test
US20110269712A1,CCOC(=O)CBr.CCc1cc(C(F)(F)F)n[nH]1>>CCOC(=O)Cn1nc(C(F)(F)F)cc1CC,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20090176778A1,NCc1cccs1.O=C(O)c1nc2c(C(F)(F)F)cc(Br)cn2c1[N+](=O)[O-]>>O=C(NCc1cccs1)c1nc2c(C(F)(F)F)cc(Br)cn2c1[N+](=O)[O-],,CCOC(C)=O,CN(C)C=O,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20100112090A1,COc1ccc(F)c(F)c1CBr.O=[N+]([O-])c1cc(O)c(O)cc1Cl>>COc1ccc(F)c(F)c1COc1cc([N+](=O)[O-])c(Cl)cc1O,,CN(C)C=O,O,Cl,[H-].[Na+],test
US20070265321A1,O=S1(=O)CCC(COCc2ccccc2)N1>>O=S1(=O)CCC(CO)N1,[Pd],CC(=O)OC(C)C,,,,test
US20070105943A1,N#Cc1ccc(CNc2ccccc2)cc1>>NCc1ccc(CNc2ccccc2)cc1,,C1CCOC1,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20050288232A1,CCOC(=O)[C@H](O)CCc1ccccc1>>O=C(O)[C@H](O)CCc1ccccc1,,CCO,,[Na+].[OH-],,test
US20070287701A1,O=c1cc[nH]c2c(Br)cc3c(c12)OCCO3>>O=c1cc[nH]c2ccc3c(c12)OCCO3,[Pd],C1COCCO1,O,[Na+].[OH-],,test
US20100168080A1,COc1cc(OCCBr)c([N+](=O)[O-])cc1Cl>>COc1cc(OCCBr)c(N)cc1Cl,,CCO,,Cl[Sn]Cl,,test
US20100087429A1,Cc1ccc(B(O)O)cc1.NC1=N[C@@]2(CO1)c1cc(O)ccc1Oc1ncc(Br)cc12>>Cc1ccc(-c2cnc3c(c2)[C@]2(COC(N)=N2)c2cc(O)ccc2O3)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,,,O=C([O-])[O-].[K+].[K+],,test
US06329405B1,COc1c(OC)c(=O)c1=O.COc1ccc(C(NCCc2ccccc2)c2cccc(N)c2)cc1>>COc1ccc(C(NCCc2ccccc2)c2cccc(Nc3c(OC)c(=O)c3=O)c2)cc1,,CO,,,,test
US20140200231A1,O=C(O)COCCc1cnnn1Cc1ccccc1>>O=C(O)COCCc1cnn[nH]1,Cl[Pd]Cl,CC(C)O,O,[H][H],,test
US20060084815A1,CC(C)(C)C=O.CCOc1cc([C@@H](CC(=O)N(C)C)N2Cc3cccc(N)c3C2=O)ccc1OC>>CCOc1cc([C@@H](CC(=O)N(C)C)N2Cc3cccc(NCC(C)(C)C)c3C2=O)ccc1OC,,ClCCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20150038492A1,CC(C)(C)OC(=O)N[C@H]1CCCC[C@H]1Nc1nc(Nc2cccc(-n3nccn3)c2)c(C(N)=O)cc1C#N.OO>>NC(=O)c1cc(C(N)=O)c(N[C@@H]2CCCC[C@@H]2N)nc1Nc1cccc(-n2nccn2)c1,,CS(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US04012380,O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)OC(c3ccccc3)c3ccccc3)=C(C(=O)c3ccccc3)CS[C@H]12>>O=C(Cc1cccs1)NC1C(=O)N2C(C(=O)O)=C(C(=O)c3ccccc3)CS[C@H]12,,CCCCCCC,,COc1ccccc1,O=C(O)C(F)(F)F,test
US20060128734A1,CCOC(=O)CC(=O)Cc1ccc(NC(=O)OC(C)(C)C)cc1.NC(N)=S>>CC(C)(C)OC(=O)Nc1ccc(Cc2cc(O)nc(S)n2)cc1,,CCCCO,O,Cl,CC(C)(C)[O-].[K+],test
US20090209524A1,CCCC[C@@H](CC(=O)OC(C)(C)C)N(Cc1ccccc1)[C@@H](C)c1ccccc1>>CCCC[C@@H](CC(=O)O)N(Cc1ccccc1)[C@@H](C)c1ccccc1,,ClCCl,,O=C(O)C(F)(F)F,,test
US20150175602A1,CC(C)(C)OC(=O)N1CCC(Sc2ccccc2F)CC1.O=S([O-])OO>>CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccccc2F)CC1,,C1CCOC1,CO,O,,test
US04308266,COC1C(=O)CCc2ccccc21.Cc1ccccc1N1CCNCC1>>COc1ccc2c(c1)CCC(N1CCN(c3ccccc3C)CC1)C2,,Cc1ccccc1,,Cc1ccc(S(=O)(=O)O)cc1,,test
US04122179,CC(=O)Oc1ccccc1C(=O)O.CC[C@]12CCCN3CCc4c(n(c5ccccc45)[C@@](O)(C(=O)OC)C1)[C@@H]32>>CC(=O)Oc1ccccc1C(=O)[O-].CC[C@]12CCCN3CCc4c(n(c5ccccc45)[C@@](O)(C(=O)OC)C1)[C@@H]32,,CCO,ClC(Cl)Cl,,,test
US20100075948A1,CC(C)(C)CC1NC(C(=O)O)C(c2cccc(Cl)c2F)C1(C#N)c1ccc(Cl)cc1F.NC(=O)c1cccc(N)c1>>CC(C)(C)C[C@@H]1N[C@@H](C(=O)Nc2cccc(C(N)=O)c2)[C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F,,CO,ClCCl,CCN(C(C)C)C(C)C,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20090142279A1,C[C@H]1CN(Cc2cccc(-c3cc(CNC(=O)c4cccc(CC5CCN(C(=O)OC(C)(C)C)CC5)c4)ccc3F)c2)CCN1C>>C[C@H]1CN(Cc2cccc(-c3cc(CNC(=O)c4cccc(CC5CCNCC5)c4)ccc3F)c2)CCN1C,,C1COCCO1,,Cl,,test
US05607624,CC(C)(C)c1cc2c(c(C(C)(C)C)c1)OC(=O)C2O.c1ccccc1>>CC(C)(C)c1cc2c(c(C(C)(C)C)c1)OC(=O)C2c1ccccc1,,O,,Cl,[Al+3].[Cl-].[Cl-].[Cl-],test
US06194410B1,CSc1nn2c(Cl)cc(C)nc2c1S(=O)(=O)c1ccc(Cl)cc1.N>>CSc1nn2c(N)cc(C)nc2c1S(=O)(=O)c1ccc(Cl)cc1,,CO,,,,test
US20090105227A1,COC(=O)c1cc2[nH]c(Br)c(C3CCCCC3)c2s1.COCCl>>COCn1c(Br)c(C2CCCCC2)c2sc(C(=O)OC)cc21,,CN(C)C=O,,[H-].[Na+],,test
US20040176597A1,CC(=O)OC1=CC(c2ccccc2)N(C(C)=O)c2c1ccn1c(C)c(C)nc21>>CC(=O)N1c2c(ccn3c(C)c(C)nc23)[C@@H](O)C[C@H]1c1ccccc1,,CO,ClCCl,[BH4-].[Na+],[Cl-].[NH4+],test
US20090286812A1,CC(C)(C)OC(=O)N1CCC(n2ncc3c(Oc4ccc(S(C)(=O)=O)cc4F)ncnc32)CC1.O=C(O)C(F)(F)F>>CS(=O)(=O)c1ccc(Oc2ncnc3c2cnn3C2CCNCC2)c(F)c1.O=C(O)C(F)(F)F,,ClCCl,,CO,,test
US05541178,C=CCBr.Nc1ccc([N+](=O)[O-])c(C(=O)O)c1>>C=CCOC(=O)c1cc(N)ccc1[N+](=O)[O-],,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20020193535A1,Cc1ccc(NN)cc1.O=C1CCc2ccccc21>>Cc1ccc2[nH]c3c(c2c1)Cc1ccccc1-3,,CCO,,Cl,Cl,test
US20050124630A1,BrC1C2CCC1CC2.O=C=O>>O=C(O)C1C2CCC1CC2,,C1CCOC1,,[Li],,test
US20040106667A1,CS(=O)(=O)c1ccccc1S(=O)(=O)Nc1ccc2[nH]nc(/C=C/c3ccc(F)cc3)c2c1>>CS(=O)(=O)c1ccccc1S(=O)(=O)Nc1ccc2[nH]nc(CCc3ccc(F)cc3)c2c1,[Pd],CN(C)C=O,,[H][H],,test
US20120252842A1,CCOC(=O)CCCBr.COc1cc2c(cc1O)C(=O)CC2>>CCOC(=O)CCCOc1cc2c(cc1OC)CCC2=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20080255083A1,O=C(Cn1ccc(OCc2ccccc2)cc1=O)c1cc2c(s1)CCN(Cc1ccccc1Cl)C2>>O=C(Cn1ccc(OCc2ccccc2)cc1=O)c1cc2c(s1)CCNC2,,ClCCl,,CC(Cl)OC(=O)Cl,,test
US20140371203A1,C1CCNC1.COCC1CCN(c2nc(CC(=O)O)nc3scc(-c4ccccc4)c23)CC1>>COCC1CCN(c2nc(CC(=O)N3CCCC3)nc3scc(-c4ccccc4)c23)CC1,,CC#N,,CCN(CC)CC,CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F,test
US20130040978A1,CC(C)(C)NN.O=C(Cc1ccc(F)c(F)c1F)c1ccccc1>>CC(=NNC(C)(C)C)c1ccc(F)c(F)c1F,,CCO,,Cl,CC(=O)[O-].[Na+],test
US20030027840A1,C=C(OCC)[Sn](CCCC)(CCCC)CCCC.CCCCC12CCC(=O)C(Br)=C1c1ccc(OC)c(Cl)c1C2>>C=C(OCC)C1=C2c3ccc(OC)c(Cl)c3CC2(CCCC)CCC1=O,Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1,Cc1ccccc1,,,,test
US08476253B2,CC(C)(C)C(=O)Cl.CCN(CC)CC.CN(CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1)C(=O)CCCCCNc1ccc(C(=O)N2CCNCC2)cc1.O=C(O)CO[C@H]1Cc2ccccc2C12CCN(CC[C@@]1(c3ccc(F)cc3)CN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CO1)CC2>>CN(CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1)C(=O)CCCCCNc1ccc(C(=O)N2CCN(C(=O)CO[C@H]3Cc4ccccc4C34CCN(CC[C@@]3(c5ccc(F)cc5)CN(C(=O)c5cc(C(F)(F)F)cc(C(F)(F)F)c5)CO3)CC4)CC2)cc1.O=C[O-].[NH4+],,ClCCl,,,,test
US20020187994A1,CC(=O)OC(C)(C)C.O=C1CN2CCC1CC2>>CC(C)(C)OC(=O)CC1(O)CN2CCC1CC2,,C1CCOC1,O,CC(C)NC(C)C,[Li]CCCC,test
US03963717,CC(C)I.Nc1ccc2c(c1)CCO2>>CC(C)Nc1ccc2c(c1)CCO2,,CCN(CC)CC,,CO,,test
US20030114666A1,CN(C)C=O.Cc1c(Cl)ncc(C(=O)O)c1Cl>>Cc1c(Cl)ncc(C(N)=O)c1Cl,,ClCCl,,O=C(Cl)C(=O)Cl,,test
US04100152,N[C@@H](CSCC(=O)O)C(=O)O>>O=C1CSCC(C(=O)O)N1,,O,,[Na+].[OH-],,test
US04151179,CCOC(=O)C(C)c1ccc2oc(C(C)(C)C)cc(=O)c2c1>>CCOC(=O)C(C)c1ccc2c(c1)C(=O)CC(C(C)(C)C)O2,[Pd],CC(C)=O,CCO,O=S(=O)(O)O,O=[Cr](=O)=O,test
US20150239895A1,CC(C)(C)OC(=O)Cn1nc(C(N)=O)c2cc(Br)ccc21.CC1(C)OB(c2cn[nH]c2)OC1(C)C>>CC(C)(C)OC(=O)Cn1nc(C(N)=O)c2cc(-c3cn[nH]c3)ccc21,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20090239876A1,COC(=O)C(=CN(C)C)C(=O)NCc1ccc(Br)cc1.N=C(N)n1cccn1>>O=C(NCc1ccc(Br)cc1)c1cnc(-n2cccn2)nc1O,,CC(=O)N(C)C,CCOC(C)=O,C1CCC2=NCCCN2CC1,Cl,test
US20130059834A1,Cn1nc(-c2cnc3c(n2)c(C(=O)N[C@@H]2CC[C@@H](O)CC2)cn3COCC[Si](C)(C)C)c2ccc(Cl)cc21>>Cn1nc(-c2cnc3[nH]cc(C(=O)N[C@@H]4CC[C@@H](O)CC4)c3n2)c2ccc(Cl)cc21,,ClCCl,,NCCN,O=C(O)C(F)(F)F,test
US06011046,COc1c(OC(C)=O)c(C)c2c(c1OC)OC(C)(CBr)C2>>COc1c(O)c(C)c2c(c1OC)OC(C)(CBr)C2,,CO,,Cl,[Na+].[OH-],test
US20140038910A1,CCOC(=O)CC(NC(=O)CNC(=O)OC(C)(C)C)c1cc(C(C)(C)C)cc(C(C)(C)C)c1.Cl>>CCOC(=O)C[C@H](NC(=O)CN)c1cc(C(C)(C)C)cc(C(C)(C)C)c1.Cl,,C1COCCO1,,,,test
US04198347,CC(C)=C=CBr.CCOC(=O)CC(=O)OCC>>C#CC(C)(C)C(C(=O)OCC)C(=O)OCC,,CCO,,O,[Na],test
US20050107364A1,CC(C)=CCC(C)(C(=O)OCc1ccccc1)c1ccccc1>>CC(C)CCC(C)(C(=O)O)c1ccccc1,[Pd],CCOC(C)=O,,,,test
US03943149,CCOC(=O)C(C)(C)Oc1cccc2c1C[C@H](O)[C@H](O)C2>>CC(C)(Oc1cccc2c1C[C@H](O)[C@H](O)C2)C(=O)O,,CO,,[K+].[OH-],,test
US20110059943A1,CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(NC(=S)NC(=O)c3ccccc3)nc21>>CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(NC(N)=S)nc21,,CCO,,[Na+].[OH-],,test
US20050256099A1,Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCN(C)CC3)CC2)cc(N)c1N.O=CC1CC1>>Cc1cc(C[C@@H](OC(=O)N2CCC(N3CCc4ccccc4NC3=O)CC2)C(=O)N2CCC(N3CCN(C)CC3)CC2)cc2nc(C3CC3)[nH]c12,,CN(C)C=O,,,,test
US20080058357A1,CC(C)=O.Nc1ncccn1>>CC(C)Nc1ncccn1,,CCO,,CC(=O)O,,test
US20090075869A1,C=C[Sn](CCCC)(CCCC)CCCC.O=c1cc(-c2ccccc2)[nH]c2ccc(Br)cc12>>C=Cc1ccc2[nH]c(-c3ccccc3)cc(=O)c2c1,,CS(C)=O,,CCOC(C)=O,O,test
US04472433,O=C1Cc2cccc(Oc3ccccn3)c2N1.[Na+].[OH-]>>Nc1c(CC(=O)[O-])cccc1Oc1ccccn1.[Na+],,O,,C1COCCO1,,test
US20100158818A1,CCN(CC)CCC(C)(C)N.O=C(OCc1ccccc1)ON1C(=O)CCC1=O>>CCN(CC)CCC(C)(C)NC(=O)OCc1ccccc1,,C1CCOC1,,,,test
US20070197622A1,CC(C)(C)[Si](C)(C)Cl.CN(C)S(=O)(=O)n1ccnc1.O=Cc1ccccc1>>CN(C)S(=O)(=O)n1cc(C(O)c2ccccc2)nc1[Si](C)(C)C(C)(C)C,,C1CCOC1,CCCCCC,[Li]CCCC,,test
US06084130,CCCN(CCC)[C@@H]1CCc2ccc(CN)cc2C1.Cn1cnc(S(=O)(=O)Cl)c1>>CCCN(CCC)[C@@H]1CCc2ccc(CNS(=O)(=O)c3cn(C)cn3)cc2C1,,C1CCOC1,,CCN(CC)CC,,test
US20140142082A1,COC(=O)C(C)(C)CNS(=O)(=O)c1cc(-c2ccc(S(=O)(=O)NC(C)(C)C)c(C(C)(C)C)c2)n(CC2CCCCC2)c1C>>Cc1c(S(=O)(=O)NCC(C)(C)C(=O)O)cc(-c2ccc(S(=O)(=O)NC(C)(C)C)c(C(C)(C)C)c2)n1CC1CCCCC1,,CO,,[Na+].[OH-],,test
US04221788,CCBr.Clc1ccc(CC2CCCCCN2)cc1>>CCN1CCCCCC1Cc1ccc(Cl)cc1,,CCC(C)=O,,O,O=C([O-])[O-].[K+].[K+],test
US04086219,CC(C)C[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O.Cl>>CC(C)C[C@H](NC(=O)[C@H](N)Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O.Cl,[Pd],CO,,,,test
US04093631,CC1(C)CC(c2cccc3ccccc23)c2ccc(OCC3CO3)cc2O1.CNC>>CN(C)CC(O)COc1ccc2c(c1)OC(C)(C)CC2c1cccc2ccccc12,,CCO,,,,test
US06399627B1,N#Cc1cccc(C(=O)CBr)c1.c1cn[nH]c1>>N#Cc1cccc(C(=O)Cn2cccn2)c1,,ClCCl,,CCN(CC)CC,,test
US20150065705A1,COC(=O)c1ccc(CO)nc1.O=S(=O)(OCC(F)(F)F)C(F)(F)F>>COC(=O)c1ccc(COCC(F)(F)F)nc1,,CCOC(C)=O,O,CN(C)C=O,[H-].[Na+],test
US04290947,CC(=O)OCc1ccccc1.C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1C(=O)N([Si](C)(C)C(C)(C)C)[C@@H]1CC=O>>C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1C(=O)N([Si](C)(C)C(C)(C)C)[C@@H]1CC(O)CC(=O)OCc1ccccc1,,C1CCOC1,,CC(C)NC(C)C,[Li]CCCC,test
US20020016337A1,CC(C)(C)OC(=O)N1CCC[C@@H](C(=O)Nc2ccccc2)C1>>CC(C)(C)OC(=O)N1CCC[C@H](CNc2ccccc2)C1,,C1CCOC1,,B,,test
US20130210802A1,C1COCCN1.O=[N+]([O-])c1ccc(Br)cn1>>O=[N+]([O-])c1ccc(N2CCOCC2)cn1,,CC#N,,CCN(C(C)C)C(C)C,,test
US20090023745A1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COC(=O)C(C)(C)CNCCC#N>>COC(=O)C(C)(C)CN(CCC#N)C(=O)OC(C)(C)C,,C1CCOC1,,,,test
US20140364414A1,CS(=O)(=O)O.c1cncc(-c2cnc(N3CCOCC3)c3nc(COc4ccc5ccccc5n4)cn23)c1>>CS(=O)(=O)O.c1cncc(-c2cnc(N3CCOCC3)c3nc(COc4ccc5ccccc5n4)cn23)c1,,ClCCl,,,,test
US08748462B2,C=CC1(c2cc(CO)ccc2-c2cc(OC)ncc2F)CCCC1.O=S(Cl)Cl>>C=CC1(c2cc(CCl)ccc2-c2cc(OC)ncc2F)CCCC1,,CN(C)C=O,ClCCl,,,test
US04027027,Cc1ccccc1OCC(O)CN(CCOc1ncccc1C(N)=O)Cc1ccccc1>>Cc1ccccc1OCC(O)CNCCOc1ncccc1C(N)=O,[Pd],CCO,,[H][H],,test
US20150225449A1,COc1ccc2cc(Br)ccc2c1CN1C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)OC(C)(C)C)[C@H](C)N(C(=O)CS(C)(=O)=O)c2ccccc21.Cl>>CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)[C@H]1C.Cl,,CCOCC,CO,,,test
US04661607,O=c1c2ccccc2oc2cc(O)c(Cl)cc12.OCCBr>>O=c1c2ccccc2oc2cc(OCCO)c(Cl)cc12,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20110021779A1,Cc1cc(F)ccc1C#N.OC1CCNCC1>>Cc1cc(OC2CCNCC2)ccc1C#N,,C1CCOC1,COC(C)(C)C,CC(C)(C)[O-].[K+],,test
US20150246923A1,COc1cc2c(cc1-c1c(C)noc1C)[nH]c1ncnc(Cl)c12.Cn1nc(N)c2ccccc21>>COc1cc2c(cc1-c1c(C)noc1C)[nH]c1ncnc(Nc3nn(C)c4ccccc34)c12,Cl,CC(C)O,,O=C(O)C(F)(F)F,,test
US06153613,CCOC(=O)CC(c1cccnc1)N1CCN(CCCOc2ccc(C(=N)NC(=O)OC(C)(C)C)cc2)C(=O)C1=O.Cl>>CCOC(=O)CC(c1cccnc1)N1CCN(CCCOc2ccc(C(=N)N)cc2)C(=O)C1=O.Cl,,C1COCCO1,CCOC(C)=O,,,test
US20130109662A1,C=C1CC(=O)O1.COC(=O)CN>>COC(=O)CNC(=O)CC(C)=O,,Cc1ccccc1,,Cl,O=C([O-])O.[Na+],test
US20020061996A1,CCOc1cc(/C=C/C(=O)OC)ccc1O.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F>>CCOc1cc(/C=C/C(=O)OC)ccc1OS(=O)(=O)C(F)(F)F,,ClCCl,,CCN(CC)CC,,test
US20070167444A1,CNc1ncc([N+](=O)[O-])cc1Cl>>CNc1ncc(N)cc1Cl,[Fe],CCO,,CC(=O)O,[Na+].[OH-],test
US20090111840A1,CC(C)(C)OC(=O)N1CCCC2(CCN(Cc3ccccc3)C2)C1CN>>NCC1NCCCC12CCN(Cc1ccccc1)C2,,ClCCl,,O=C(O)C(F)(F)F,O=C([O-])O.[Na+],test
US20120010190A1,COc1ccc(C(=O)CC(c2ccc(Br)cc2F)C2CCCC2)cn1>>O=C(CC(c1ccc(Br)cc1F)C1CCCC1)c1ccc(=O)[nH]c1,,C1COCCO1,,Cl,,test
US20160272592A1,COCc1ccc(C2CC2)c(CN)c1.Cc1ncc(-c2nn(-c3ccccc3)c(N)c2C)cn1.O=C(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl>>COCc1ccc(C2CC2)c(CNC(=O)Nc2c(C)c(-c3cnc(C)nc3)nn2-c2ccccc2)c1,,ClCCl,,CCN(C(C)C)C(C)C,,test
US20090275578A1,CCc1ccc(CN)cc1.COC(=O)c1c(CBr)cc(F)cc1C(F)(F)F>>CCc1ccc(CN2Cc3cc(F)cc(C(F)(F)F)c3C2=O)cc1,,CCCCCC,Cc1ccccc1,CCOC(C)=O,O=C([O-])[O-].[K+].[K+],test
US20150158863A1,Brc1ccccn1.OB(O)c1ccc(O)cc1>>Oc1ccc(-c2ccccn2)cc1,c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1,O,,COCCOC,O=C([O-])[O-].[Na+].[Na+],test
US04145432,CCOC(=O)CC(=O)C(OCC)OCC.O=Cc1cccs1>>CCOC(=O)C(=Cc1cccs1)C(=O)C(OCC)OCC,C1CCNCC1,c1ccccc1,,CCOCC,,test
US20080176857A1,CCc1cc2c(N3CCNCC3)nc(SCC(=O)OC)nc2s1.COCCC(=O)Cl>>CCc1cc2c(N3CCN(C(=O)CCOC)CC3)nc(SCC(=O)OC)nc2s1,,CN1CCCC1=O,,CCN(C(C)C)C(C)C,Cl,test
US04343811,C(=C1CCCCCN1)c1ccncc1.O=C1C=CC(=O)C=C1>>Oc1ccc2c(-c3ccncc3)c3n(c2c1)CCCCC3,,ClC(Cl)Cl,,,,test
US06515011B2,COc1ccc(NC(c2ccc(Cl)cc2CNC(=O)[C@@H]2CCCN2)C(F)(F)F)cc1.O=C(O)[C@H](O)C1CCCCC1>>NC(=O)[C@@H]1CCCN1C(=O)[C@H](O)C1CCCCC1,,CN(C)C=O,,ClCCCl,On1nnc2cccnc21,test
US20030220516A1,CC(OB([O-])c1ccc(C=O)cc1)C(C)(C)C>>OCc1ccc(B(O)O)cc1,,CO,,,,test
US20110112065A1,CCCN.Fc1cc(Br)cc2c1COC(CBr)O2>>CCCNCC1OCc2c(F)cc(Br)cc2O1,,CCO,,,,test
US05872115,CCCCCCCNC(=O)Nc1ccccc1C(=O)NC1CCNCC1.COCc1c(C(C)C)nc(C(C)C)c(C=O)c1-c1ccc(F)cc1>>CCCCCCCNC(=O)Nc1ccccc1C(=O)NC1CCN(Cc2c(C(C)C)nc(C(C)C)c(COC)c2-c2ccc(F)cc2)CC1,,CO,,O,[BH3-]C#N.[Na+],test
US20020013348A1,C=CCOC(C)(C)CC1CCN(C(=O)OC(C)(C)C)CC1>>CCCOC(C)(C)CC1CCNCC1,[Pd],CO,,,,test
US20130059834A1,CC(C)(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(CC4CN(C(=O)OC(C)(C)C)C4)c4cc(F)ccc34)nc12.O=C(O)C(F)(F)F>>CC(C)(C)NC(=O)c1c[nH]c2ncc(-c3nn(CC4CNC4)c4cc(F)ccc34)nc12.O=C(O)C(F)(F)F,,ClCCl,,,,test
US20060069106A1,CCOc1ccc(-n2c([C@@H](C)N)nc3c(c2=O)CCCN3C(C)=O)cc1.Cc1cc(CBr)n(C)n1>>CCOc1ccc(-n2c([C@@H](C)NCc3cc(C)nn3C)nc3c(c2=O)CCCN3C(C)=O)cc1,,CN(C)C=O,,O=C([O-])[O-].[K+].[K+],,test
US20160007602A1,CC(=O)OCBr.COc1ccnc(C(=O)N[C@H]2CCO[C@H](CCc3ccccc3)[C@@H](Cc3ccc(F)cc3)[C@H](C)OC2=O)c1O>>COc1ccnc(C(=O)N[C@H]2CCO[C@H](CCc3ccccc3)[C@@H](Cc3ccc(F)cc3)[C@H](C)OC2=O)c1OCOC(C)=O,,CC(C)=O,,O=C([O-])[O-].[K+].[K+],,test
US20130196974A1,Cc1ccc2nc(Cl)nc(NCC3COC(C)(C)O3)c2c1.O=S1(=O)CCNCc2ccccc21>>Cc1ccc2nc(N3CCS(=O)(=O)c4ccccc4C3)nc(NCC(O)CO)c2c1,,CN(C)C=O,CO,CCN(CC)CC,Cl,test
US04110113,CCCCCCCCCCCCCCCCS(=O)(=O)Nc1cc(OC)c(NC(C)=O)cc1OC>>CCCCCCCCCCCCCCCCS(=O)(=O)Nc1cc(OC)c(N)cc1OC,,CCO,,Cl,,test
US20040235826A1,CS(=O)(=O)N1CCNCC1.O=CCc1ccc2[nH]c(-c3cc4ccccc4[nH]c3=O)cc2c1>>CS(=O)(=O)N1CCN(CCc2ccc3[nH]c(-c4cc5ccccc5[nH]c4=O)cc3c2)CC1,,ClCCCl,,CC(=O)O,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],test
US04362728,Clc1ncccn1.NCCCCc1csc(NC(N)=NCC(F)(F)F)n1>>NC(=NCC(F)(F)F)Nc1nc(CCCCNc2ncccn2)cs1,,CC#N,,,,test
US20060264460A1,N#Cc1cnc2ccc(N)cc2c1NC1CCCCCC1.O=Cc1cccnc1>>N#Cc1cnc2ccc(NCc3cccnc3)cc2c1NC1CCCCCC1,,CCO,,[BH3-]C#N.[Na+],,test
US20050148640A1,N#Cc1nonc1N.O=C(OC(=O)C(F)(F)F)C(F)(F)F>>N#Cc1nonc1NC(=O)C(F)(F)F,CN(C)c1ccncc1,ClCCl,,,,test
US05045563,Brc1cccc2ccccc12.Brc1cccs1>>c1csc(-c2cccc3ccccc23)c1,,CCOCC,,II,[Mg],test
US20100173901A1,CC(C)(C)[Si](C)(C)Oc1ccc2cccnc2c1>>CC(C)(C)[Si](C)(C)Oc1ccc2c(c1)NCCC2,[Pd],,,CO,,test
US20030220373A1,ClCc1cccc(OCc2ccc3ccccc3n2)c1.N#Cc1cccc(O)c1>>N#Cc1cccc(OCc2cccc(OCc3ccc4ccccc4n3)c2)c1,,CN(C)C=O,,O,O=C([O-])[O-].[K+].[K+],test
US20110245205A1,O=[N+]([O-])c1cc(-c2cnc(C(O)(C3CC3)C3CC3)s2)cc(N2CCOCC2)c1>>Nc1cc(-c2cnc(C(O)(C3CC3)C3CC3)s2)cc(N2CCOCC2)c1,[Pd],CCOC(C)=O,,CC(=O)O,,test
US20150126490A1,Nc1cnc(C2=CCC3(CC2)OCCO3)cn1>>Nc1cnc(C2CCC3(CC2)OCCO3)cn1,[Pd],CO,,[H][H],,test
US20100210633A1,COc1cc(C=O)ccc1O.O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1(CC2CC2)CCNC1>>COc1cc(CN2CCC(CC3CC3)(C(=O)NCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)C2)ccc1O,,ClCCl,,CC(=O)O[BH-](OC(C)=O)OC(C)=O.[Na+],,test
US20110028466A1,CC(C)[Si](Cl)(C(C)C)C(C)C.O=[N+]([O-])c1cn(CCC(O)CO)c(Br)n1>>CC(C)[Si](OCC(O)CCn1cc([N+](=O)[O-])nc1Br)(C(C)C)C(C)C,,CN(C)C=O,,c1c[nH]cn1,,test
USRE028939,O=CNc1n[nH]c2ccc(C(F)(F)F)cc12>>CNc1n[nH]c2ccc(C(F)(F)F)cc12,,CCOCC,,O,[Al+3].[H-].[H-].[H-].[H-].[Li+],test
US20080009530A1,NCCc1cccs1.O=C=NS(=O)(=O)Cl.OCc1ccccc1>>O=C(NS(=O)(=O)NCCc1cccs1)OCc1ccccc1,,ClCCl,c1ccncc1,Cl,,test
US04232029,CC(=O)C(CN(C)C)=NO.Cc1ccc(C=O)cc1.[NH4+]>>Cc1ccc(-c2nc(C)c(CN(C)C)n2O)cc1,,CO,,Cl,,test
US20150376195A1,COC(=O)[C@@H]1CCCN1C(=O)OC(C)(C)C.ClCOCc1ccccc1>>COC(=O)C1(COCc2ccccc2)CCCN1C(=O)OC(C)(C)C,,C1CCOC1,,C[Si](C)(C)[N-][Si](C)(C)C.[Li+],,test
US20140378446A1,Brc1ccc(OCc2ccccc2)cc1.CC(C)OB(OC(C)C)OC(C)C>>OB(O)c1ccc(OCc2ccccc2)cc1,,C1CCOC1,,[Li]CCCC,,test
US20120016092A1,Cc1cccc(C)c1Nc1cccc2ccc(/C=N/c3c(C(C)C)cccc3C(C)C)nc12.[Li]c1ccccc1>>Cc1cccc(C)c1Nc1cccc2ccc(C(Nc3c(C(C)C)cccc3C(C)C)c3ccccc3)nc12,,C1CCOC1,,,,test
US20100311714A1,CCOc1cc(Br)cnc1C.O=C(OO)c1cccc(Cl)c1>>CCOc1cc(Br)c[n+]([O-])c1C,,ClCCl,,,,test
US20020082265A1,CC1(C)CCC(C)(C)c2cc(C=O)c(C#Cc3ncccn3)cc21>>CC1(C)CCC(C)(C)c2cc(CCc3ncccn3)c(C=O)cc21,[Pd],CCO,,[H][H],,test
US20050004014A1,CCCCC1(OC)CCN(c2ccc(-c3nnc(-c4ccc(CO)cc4)s3)cc2)CC1>>CCCCC1(OC)CCN(c2ccc(-c3nnc(-c4ccc(C=O)cc4)s3)cc2)CC1,,ClC(Cl)Cl,,,,test
US20090270350A1,COc1cccc(Cn2c(C)cc(O)cc2=O)c1.O=C1c2ccccc2C(=O)N1Cc1ccccc1CCl>>COc1cccc(Cn2c(C)cc(OCc3ccccc3CN3C(=O)c4ccccc4C3=O)cc2=O)c1,,CN(C)C=O,,C1CCC2=NCCCN2CC1,O,test
US20080167287A1,CCOC(=O)c1cnn(-c2cnc3ncc(C4(c5ccc6ncccc6c5)CC4)n3c2)c1>>O=C(O)c1cnn(-c2cnc3ncc(C4(c5ccc6ncccc6c5)CC4)n3c2)c1,,CO,O,Cl,[Li+].[OH-],test
US03960872,C1CCNCC1.CN1CCC(=C2c3ccccc3C=C(Br)c3ccccc32)CC1>>CN1CCC(=C2c3ccccc3C=C(N3CCCCC3)c3ccccc32)CC1,,CC(C)(C)O,,CC(C)(C)[O-].[K+],,test
US20150158815A1,C[Si](C)(C)C#N.Nc1cncc(Br)c1.O=Cc1ccccc1Cl>>N#CC(Nc1cncc(Br)c1)c1ccccc1Cl,,COCCOC,,,,test
US20120184553A1,COC(=O)c1cc(C(=O)N2CCN(C)CC2)ccc1OCc1ccccc1>>CN1CCN(C(=O)c2ccc(OCc3ccccc3)c(C(=O)O)c2)CC1,,C1CCOC1,O,Cl,[Li+].[OH-],test
US20130096149A1,CCCS(=O)(=O)Nc1cccc(-c2nc(C(C)(C)C)sc2-c2ccnc(NC[C@H](C)NC(=O)OC(C)(C)C)n2)c1Cl>>CCCS(=O)(=O)Nc1cccc(-c2nc(C(C)(C)C)sc2-c2ccnc(NC[C@H](C)N)n2)c1Cl,,Cl,,,,test
US04935413,C=CC(=O)N=C=O.CC(C)(C)O>>C=CC(=O)NC(=O)OC(C)(C)C,,CC(Cl)Cl,,,,test
US20060084680A1,BrCCBr.CCCc1c(O)ccc2c(C(F)(F)F)noc12>>CCCc1c(OCCBr)ccc2c(C(F)(F)F)noc12,,O,,[Na+].[OH-],,test
US20100179139A1,CC(C)(C)OC(=O)N1C=C(c2cc3c(-c4ccc(S(=O)(=O)NC5CCS(=O)(=O)C5)s4)ccnc3[nH]2)CCC1.CN(C)C=O.CO>>O=CO.O=S1(=O)CCC(NS(=O)(=O)c2ccc(-c3ccnc4[nH]c(C5CCCNC5)cc34)s2)C1,,CN(C)C=O,CO,,,test
US20060287298A1,COC(=O)C1CCCCN1CCC(=O)c1ccc(F)cc1.Clc1ccc([Mg]I)cc1>>COC(=O)C1CCCCN1CCC(O)(c1ccc(F)cc1)c1ccc(Cl)cc1,,CCOCC,,,,test
US20080188513A1,CC(C)Cn1cnc2c(N)nc3cccnc3c21.CS(=O)(=O)O.O>>CC(C)Cn1cnc2c(N)nc3cccnc3c21.CS(=O)(=O)O.O,,CC(C)O,O,,,test
US07160887B1,CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.COc1cccc(CCN)c1>>CC(C)(C)OC(=O)NCCc1cccc(O)c1,,CCOCC,,Br,[Na+].[OH-],test
US20100311790A1,C#CCBr.O=C(NCc1cccc(O)c1F)c1ccc2ncccc2c1>>C#CCOc1cccc(CNC(=O)c2ccc3ncccc3c2)c1F,,O,,CN(C)C=O,O=C([O-])[O-].[Cs+].[Cs+],test
US20080242706A1,O=c1cc(C(F)F)n(C2CC2)cc1OCc1ccccc1>>O=c1cc(C(F)F)n(C2CC2)cc1O,[Pd],CO,,[H][H],,test
US20120004203A1,CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(N)nc2N1c1cccc(C(F)(F)F)c1.O=C(Cl)c1ccno1>>CC1=C(C#N)[C@@H](c2ccc(C#N)cc2)n2nc(NC(=O)c3ccno3)nc2N1c1cccc(C(F)(F)F)c1,,c1ccncc1,,Cl,,test
US20040209865A1,CC(COc1ccc(C#Cc2ccc(-c3ccc(Cl)cc3)cn2)cc1)OS(C)(=O)=O.CC1CCNCC1>>CC1CCN(C(C)COc2ccc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)cc2)CC1,,CN(C)C=O,,,,test